gebhart/patrepeval huggingface dataset:
PROMETHEUS-Projekte im Hause Daimler-Benz (1992)

Im Rahmen des europaeischen Prometheus-Forschungsprojektes sollen zukunftsweisende Informations- und Kommunikationstechniken entwickelt werden, mit denen ein entscheidender Beitrag zur Loesung der heutigen Verkehrsprobleme geleistet werden kann. An diesem Forschungsprojekt hat sich als Mitinitiator auch Daimler-Benz beteiligt. Im Bericht werden Beitraege im Detail vorgestellt, denen sich dieses Unternehmen besonders gewidmet hat. Es handelt sich dabei um Projekte zum Thema Sicheres Fahren, bei denen die unmittelbare Fahrzeugumgebung in das Fahrzeugverhalten einbezogen wird, und zum anderen um das Verkehrssystem-Management, bei dem die optimale Verkehrsraum- und Fahrzeugnutzung im Vordergrund steht. Die bislang im Rahmen des Prometheus-Projektes erzielten Loesungen muessen vor einer moeglichen Markteinfuehrung in Feldversuchen erprobt werden. Die dafuer erforderlichen Versuchsfelder werden so gewaehlt, dass neben einem Funktionsnachweis unter realen Strassenverkehrsbedingungen zugleich Pilotprojekte mit spuerbarer Auswirkung auf den Verkehr entstehen. Referat, gehalten auf der 5. Tagung Motor & Umwelt in Graz, 28. und 29. Juli 1992. Titel in Englisch: Prometheus projects at Daimler-Benz.
Multi-layer Intrusion Detection and Defence Mechanisms Based on Immunity (2008)

Recently network intrusion detection is one of the hottest research topics. Existing network-based Intrusion Detection System (IDS) has drawbacks in many aspects, among of which the two outstanding problems are the high ratio of false alarms and the lack of self-adaptation. The powerful information processing capabilities of the biological immune system, such as feature extraction, pattern recognition, learning, memory, and its distributive multi-layer defence mechanisms provide rich metaphors for designing a computer immune defence system. In this approach, the authors propose a novel multi-layer defence mechanisms based on immunity, which is capable of detecting and identifying both known and unknown intrusions, elaborating a specialized response measure. Besides that, the proposed defence mechanisms have the same learning and adaptive capability of the biological immune system, and so it is able to monitor networked computer's activities at different levels, and to improve its response under subsequent exposures to the same attack. This on-going research effort is not to mimic simply the immunology characteristics but to explore and learn valuable lessons useful for self-adaptive immune intrusion prevention systems.
Human leukocyte antigen F (HLA-F). An expressed HLA gene composed of a class I coding sequence linked to a novel transcribed repetitive element. (1990)

We describe here the isolation and sequencing of a previously uncharacterized HLA class I gene. This gene, HLA-5.4, is the third non-HLA-A,B,C gene characterized whose sequence shows it encodes an intact class I protein. RNase protection assays with a probe specific for this gene demonstrated its expression in B lymphoblastoid cell lines, in resting T cells, and skin cells, while no mRNA could be detected in the T cell line Molt 4. Consistent with a pattern of expression different from that of other class I genes, DNA sequence comparisons identified potential regulator motifs unique to HLA-5.4 and possibly essential for tissue-specific expression. Protein sequence analysis of human and murine class I antigens has identified 10 highly conserved residues believed to be involved in antigen binding. Five of these are altered in HLA-5.4, and of these, three are nonconservative. In addition, examination of the HLA-5.4 DNA sequence predicts that the cytoplasmic segment of this protein is shorter than that of the classical transplantation antigens. The 3' untranslated region of the HLA-5.4 gene contains one member of a previously undescribed multigene family consisting of at least 30 members. Northern analysis showed that several of these sequences were transcribed, and the most ubiquitous transcript, a 600-nucleotide polyadenylated mRNA, was found in all tissues and cells examined. This sequence is conserved in the mouse genome, where a similar number of copies were found, and one of these sequences was also transcribed, yielding a 600-nucleotide mRNA. The characterization of this unique HLA class I gene and the demonstration of its tissue-specific expression have prompted us to propose that HLA-5.4 be designated HLA-F.
Supplementary Figure 7 from PGC1α-Mediated Metabolic Reprogramming Drives the Stemness of Pancreatic Precursor Lesions (2023)

&lt;p&gt;Gnas induction elevates stemness feature in during IPMN development.&lt;/p&gt;
Adenosine-mediated inhibition of platelet aggregation by acadesine. A novel antithrombotic mechanism in vitro and in vivo. (1994)

Inhibition of platelet aggregation by acadesine was evaluated both in vitro and ex vivo in human whole blood using impedance aggregometry, as well as in vivo in a canine model of platelet-dependent cyclic coronary flow reductions. In vitro, incubation of acadesine in whole blood inhibited ADP-induced platelet aggregation by 50% at 240 +/- 60 microM. Inhibition of platelet aggregation was time dependent and was prevented by the adenosine kinase inhibitor, 5'-deoxy 5-iodotubercidin, which blocked conversion of acadesine to its 5'-monophosphate, ZMP, and by adenosine deaminase. Acadesine elevated platelet cAMP in whole blood, which was also prevented by adenosine deaminase. In contrast, acadesine had no effect on ADP-induced platelet aggregation or platelet cAMP levels in platelet-rich plasma, but inhibition of aggregation was restored when isolated erythrocytes were incubated with acadesine before reconstitution with platelet-rich plasma. Acadesine (100 mg/kg i.v.) administered to human subjects also inhibited platelet aggregation ex vivo in whole blood. In the canine Folts model of platelet thrombosis, acadesine (0.5 mg/kg per min, i.v.) abolished coronary flow reductions, and this activity was prevented by pretreatment with the adenosine receptor antagonist, 8-sulphophenyltheophylline. These results demonstrate that acadesine exhibits antiplatelet activity in vitro, ex vivo, and in vivo through an adenosine-dependent mechanism. Moreover, the in vitro studies indicate that inhibition of platelet aggregation requires the presence of erythrocytes and metabolism of acadesine to acadesine monophosphate (ZMP).
A partition-based Summary-Graph-Driven Method for Efficient RDF Query Processing (2015)

RDF query optimization is a challenging problem. Although considerable factors and their impacts on query efficiency have been investigated, this problem still needs further investigation. We identify that decomposing query into a series of light-weight operations is also effective in boosting query processing. Considering the linked nature of RDF data, the correlations among operations should be carefully handled. In this paper, we present SGDQ, a novel framework that features a partition-based Summary Graph Driven Query for efficient query processing. Basically, SGDQ partitions data and models partitions as a summary graph. A query is decomposed into subqueries that can be answered without inter-partition processing. The final results are derived by perform summary graph matching and join the results generated by all matched subqueries. In essence, SGDQ combines the merits of graph match processing and relational join-based query implementation. It intentionally avoids maintain huge intermediate results by organizing sub-query processing in a summary graph driven fashion. Our extensive evaluations show that SGDQ is an effective framework for efficient RDF query processing. Its query performance consistently outperforms the representative state-of-the-art systems.
Intérêt de la viande pour les personnes âgées : Prévention de la malnutrition et de la sarcopénie (2016)

Atelier actualités et qualité des produits:12H00-13H00 Viande et santé : risque cardio-vasculaire, cancer, sarcopénie<br/>Atelier actualités et qualité des produits:12H00-13H00Viande et santé : risque cardio-vasculaire, cancer, sarcopénie
Determination of Critical Micelle Concentration of Macroemulsions and Miniemulsions (1998)

Critical micelle concentrations (cmc's) of macroemulsion (styrene + SDS + water) and miniemulsion (styrene + DMA + SDS + water + NaHCO3) solutions are determined by a conductance technique. A four-terminal cell and an impedance spectrometer are employed in this work. An equivalent circuit of the sample cell is determined, and the solution resistance is obtained from the impedance plane plot. Cmc's of the macro-/miniemulsions are then determined from the slope break in the conductivity−surfactant concentration (κ−C) diagram. The cmc of the macroemulsion is found to be only 10% greater than that of the sodium dodecyl sulfate (SDS) surfactant solution, whereas the cmc of the miniemulsion is about five times that of the SDS solution. The surface concentration of SDS at the styrene/water interface is evaluated from the equilibrium interfacial tension data, measured by a video-enhanced pendant drop tensiometer, and the micelle ionization degree, evaluated from the slope change in κ−C plot. A video-enhanced optical microscope is utilized to evaluate the size distribution of the emulsified monomer oil droplets. A mass balance on SDS molecules is established for the macro-/miniemulsion systems. The increase of cmc is primarily due to the adsorption of SDS onto the styrene/water interface of these tiny monomer droplets in the bulk phase of the macro-/miniemulsion solutions.
Hybrid controllers for tracking of impulsive reference state trajectories (2011)

We study the problem of designing controllers to track state trajectories for plants with jumps in the state that are given by constrained differential equations capturing the continuous dynamics and constrained difference equations (or inclusions) capturing the discrete dynamics. The reference trajectories consist of signals having intervals of flow and instantaneous jumps, and are generated via a known hybrid exosystem. The class of controllers considered are hybrid and are designed to guarantee that the jump times of the plant coincide with those of the given reference trajectories. By recasting the tracking problem as the stabilization of a set and using asymptotic stability tools for time invariant hybrid systems, we derive sufficient conditions for the closed-loop system that guarantee tracking of reference trajectories.
On Generation of Chaotic M-Sequences (2005)

This paper deals with the linear generation methods of binary and decimal-valued maximal-length sequences. We show their topological equivalence, provide necessary and sufficient conditions for that and find a matrix-homeomorphism whose rows are the consecutive Rademacher sequences. We investigate a number of maximal linear sequences and give its formula. We demonstrate different patterns generated from the sequences, classify them and especially focus on ones whose shapes are similar to chaotic real-valued maps. It gives us an opportunity to establish a similarity in the statistical characteristics of both m-bit decimal integer and chaotic real-valued sequences on the one hand and design a m-sequence generator with given autocorrelation properties on the other one.
A Multi-Step Process for Generating Multi-Platform User Interfaces using UIML (2001)

There has been a widespread emergence of computing devices in the past few years that go beyond the capabilities of traditional desktop computers. These devices have varying input/output characteristics, modalities and interaction mechanisms. However, users want to use the same kinds of applications and access the same data and information on these appliances that they can access on their desktop computers. The user interfaces for these devices and platforms go beyond the traditional interaction metaphors. It is a challenge to build User Interfaces (UIs) for these devices of differing capabilities that allow the end users to perform the same kinds of tasks. The User Interface Markup Language (UIML) is an XML-based language that allows the canonical description of UIs for different platforms. We present a multi-step transformation-based framework for building Multi-Platform User Interfaces using UIML. We describe the language features of UIML that facilitate the development of multi-platform UIs, the multi-step process involved in our framework and the transformations needed to build the UIs.
Anticancer Activity and In Silico ADMET Properties of 2,4,5-Trisubstitutedthiazole Derivatives (2020)

The most active compounds 6 and 9 predicted to have good oral absorption and low human serum protein binding, exhibiting no reactive functional group and probable CNS activity compared with 95% of the known oral drugs as predicted (in silico) by QikProp. Thus, compounds 6 and 9 can be considered as lead molecules for further modification and discovery of novel anticancer agents with nanomolar potency.
Testing FPGA based reconfigurable system within run time applications (2001)

We introduce a technique for testing partially reconfigurable FPGAs. The test technique is intended to be applied in reconfigurable systems in run time applications. Normally, in reconfigurable systems, each FPGA executes many tasks sequentially. Therefore, it is configured many times in run time applications. We propose that each FPGA is tested just before each configuration. The whole system remains functional because other FPGAs are still in function when the target FPGA is under test. Since the FPGA's transit time from one task to another has a direct consequence on the system delay, the test must be very fast. Therefore, the test proposed targets only a test of tiles where the majority of the data will be configured and only configurable logic blocks actually used are tested. The technique proposed targets test which is achieved within the fault tolerant system, and is very useful in some critical applications with time and resources constraints.
Integrated multi-sensor package (IMSP) for unmanned vehicle operations (2007)

This paper describes recent efforts to develop integrated multi-sensor payloads for small robotic platforms for improved operator situational awareness and ultimately for greater robot autonomy. The focus is on enhancements to perception through integration of electro-optic, acoustic, and other sensors for navigation and inspection. The goals are to provide easier control and operation of the robot through fusion of multiple sensor outputs, to improve interoperability of the sensor payload package across multiple platforms through the use of open standards and architectures, and to reduce integration costs by embedded sensor data processing and fusion within the sensor payload package. The solutions investigated in this project to be discussed include: improved capture, processing and display of sensor data from multiple, non-commensurate sensors; an extensible architecture to support plug and play of integrated sensor packages; built-in health, power and system status monitoring using embedded diagnostics/prognostics; sensor payload integration into standard product forms for optimized size, weight and power; and the use of the open Joint Architecture for Unmanned Systems (JAUS)/ Society of Automotive Engineers (SAE) AS-4 interoperability standard. This project is in its first of three years. This paper will discuss the applicability of each of the solutions in terms of its projected impact to reducing operational time for the robot and teleoperator.
Device mismatch limitations on the performance of an associative memory system (2002)

The performance of an associative memory based computational engine that employs static binary memory cells and an analog Winner-Takes-All circuit depends on device matching in the various components of the system. This dependence has been analyzed, leading to design criteria for choosing optimum device sizes and chip architecture. The theoretical performance of a low power CMOS chip designed to operate in the subthreshold and transition region is compared with the actual experimental results.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Dopant diffusion loss mechanism in high-birefringent-fiber fused couplers (1988)

The observation of dopant diffusion during the tapering of high-birefringent fibers that increases with initial modal birefringence is reported. The resulting reduction in the core-cladding index difference is postulated to result in an increased taper transmission loss and is shown to correspond to increased 3-dB fused-coupler insertion loss.
Individual stem cell quality in leukapheresis products is related to the number of mobilized stem cells (1996)

Peripheral blood stem cells (PBSC) are used for stem cell support in patients after intensive chemotherapy and generally permit faster hematopoietic recovery than bone marrow. The development of different protocols for chemotherapy conditioning, mobilization, and ex vivo manipulation of PBSC may potentially lead to loss of primitive hematopoietic stem cells or reduction of their quality. To characterize the frequency of different stem cell subsets and their quality per mobilized PBSC, we have studied 47 leukapheresis products (LPs) of 21 cancer patients using stroma-dependent long-term culture (LTC) and limiting dilution-type cobblestone area forming cell (CAFC) assays. A large variation in CAFC week-type frequencies between the LPs was observed. The frequencies of CAFC week 2 as a tentative indicator of progenitor cells and transiently repopulating hematopoietic stem cells ranged from 0.89 to 205 per 10(5) mobilized nucleated cells and the frequencies of more primitive CAFC week 6 varied between 0.37 and 48. The average total colony-forming cell (CFC) production per CAFC at week 6 varied between 1.2 and 730, as determined in parallel LTC. In contrast to LPs, bone marrow samples generated 4.2 to 48 CFC per CAFC at week 6. Notably, a poor stem cell quality was consistently found in LPs that contained less than 5,000 CAFC week 6 per kilogram of body weight. Frequency analyses of CFCs, CAFC subtypes, and immunophenotypic subsets showed a good level of mutual correlation, suggesting identical mobilization kinetics of different stem cell subsets. The premobilization chemotherapy intensity was directly correlated with both decreasing frequency and quality of the CAFC week 6 in LPs. The frequency of CFCs, immunophenotypic subsets, and CAFC subsets transplanted and the transplant quality as determined in LTC assays was related to the neutrophil and platelet recovery time after PBSC transplantation. Although the number of progenitor cells transplanted and the in vitro transplant quality showed the best correlation with early hematopoietic recovery, the data did not permit determination of which stem cell subsets are predominantly responsible for early posttransplantation recovery. As a result, frequency and quality analysis of stem cell subsets may be a useful tool to monitor and calibrate the efficacy of novel mobilization regimens and ex vivo manipulation of PBSC.
Double Immunochromatographic Test System for Sensitive Detection of Phycotoxins Domoic Acid and Okadaic Acid in Seawater and Seafood (2022)

In this investigation, a double immunochromatographic analysis (ICA) of two relevant phycotoxins, domoic acid (DA) and okadaic acid (OA), was developed for the first time. The ICA was performed in the indirect competitive format using gold nanoparticles conjugated with anti-species antibodies. Under optimal conditions, the instrumental detection limits/cutoffs for simultaneous detection of DA and OA were 1.2/100 and 0.1/2.5 ng/mL, respectively. The time of the assay was 18 min. The ICA was applied to test seawater and a large panel of seafood, including mussels, tiger shrimps, octopuses, whelks, crabs, and scallops. The proposed simple sample preparation method for seafood takes only 20 min. For seawater, a dilution by buffer was implemented. The assay recoveries varied from 80.8% to 124.5%. The competitive potential of the proposed technique as a tool to control natural water and seafood samples is determined by its simplicity, rapidity, and sensitivity.
Abdominal adiposity, body composition and survival after liver transplantation (2015)

Abstract Background Current measures of obesity do not accurately describe body composition. Using cross‐sectional imaging, objective measures of musculature and adiposity are possible and may inform efforts to optimize liver transplantation outcomes. Methods Abdominal visceral fat area and psoas muscle cross‐sectional area were measured on CT scans for 348 liver transplant recipients. After controlling for donor and recipient characteristics, survival analysis was performed using Cox regression. Results Visceral fat area was significantly associated with post‐transplant mortality (p &lt; 0.001; HR = 1.06 per 10 cm 2 , 95% CI : 1.04–1.09), as were positive hepatitis C status (p = 0.004; HR = 1.78, 95% CI : 1.21–2.61) and total psoas area ( TPA ) (p &lt; 0.001; HR = 0.91 per cm 2 , 95% CI : 0.88–0.94). Among patients with smaller TPA , the patients with high visceral fat area had 71.8% one‐yr survival compared to 81.8% for those with low visceral fat area (p = 0.15). At five yr, the smaller muscle patients with high visceral fat area had 36.9% survival compared to 58.2% for those with low visceral fat area (p = 0.023). Conclusions Abdominal adiposity is associated with survival after liver transplantation, especially in patients with small trunk muscle size. When coupled with trunk musculature, abdominal adiposity offers direct characterization of body composition that can aid preoperative risk evaluation and inform transplant decision‐making.