gebhart/patrepeval huggingface dataset:
Zarządzanie siecią Internetową na przykładzie firmy RWD Prospect Sp. z o.o. (2012)

Celem mojej pracy jest przedstawienie różnych metod podłączeń komputerów do sieci oraz zarządzanie nią na przykładzie firmy RWD Prospect Sp. z o.o. W pierwszym rozdziale mojej pracy opisuję przewodowe i bezprzewodowe sposoby podłączania sieci. Drugi rozdział zawiera opis mediów transmisyjnych oraz urządzeń do przesyłania danych. Kolejny rozdział zawiera charakterystykę firmy RWD Prospect Sp. z o.o. Ostatni rozdział przedstawia rozwiązania przyjęte przez firmę do zarządzania przekazywanym sygnałem Internetowym oraz jego wady i zalety. Firma RWD Prospect Sp. z o.o. posiada rozbudowaną sieć internetową, która w miarę możliwości jest modernizowana. Posiada ona więcej zalet niż wad – oznacza to, że jest prawidłowo skonstruowana, wydajna, generuje niskie koszty, a sposób dostarczenia Internetu dla klientów jest maksymalnie bezawaryjny. Dzięki temu świadczone usługi internetowe uzyskują pozytywne opinie od klientów, dające podstawę do ekonomicznego i zyskownego rozbudowywania sieci.
An Adaptive HARQ Scheme Based on Quasi-Othogonal Space-Time Coding for D-STTD System (2007)

Double space time transmit diversity (D-STTD) is a promising open loop MIMO scheme for spatial rate 2 in the system with four transmit antennas, which has been adopted in LTE and 802.16e. In this paper, we propose an adaptive HARQ scheme based on quasi-orthogonal space-time block coding (QOSTBC) for D-STTD system under quasi-static channel environment. "Adaptive" means that there are two possible coding forms of QOSTBC and one of them will be chosen according to the lower inter-antenna interference in the equivalent channel matrix. At the same time, the adaptation leads to the employment of a low-complexity linear detection at the receiver. With one-bit feedback, this adaptive HARQ scheme is demonstrated to exploit more gain than the traditional Chase- Combing or Increment Redundancy scheme.
Clinical significance and preventive strategies for contrast-induced nephropathy (2008)

Contrast-induced nephropathy is an increasing cause of acute kidney injury and is associated with significant mortality and morbidity. Future developments in this field will focus on refining the clinical significance of this complication, earlier diagnosis with biomarkers, clarifying the role for bicarbonate and iso-osmolar contrast agents as preventive strategies, and the introduction of new prophylactic techniques on the basis of an improved understanding of pathogenesis at the cellular level.
High Molecular Weight Poly(methyl methacrylate) Synthesis Using Recyclable and Reusable Zeolitic Imidazole Framework‐8 Catalyst (2020)

Abstract Here, one‐step synthesis of high molecular weight poly(methyl methacrylate) (PMMA; 1000–1650 kg mol −1 ) is reported by using zeolitic imidazole framework‐8 (ZIF‐8) catalyst without any co‐catalyst in the absence of a solvent. This type of high molecular weight PMMA has different applications, mainly in gel polymer electrolyte and bone cement. Zwitterionic type mechanism is proposed where the active acid site of the catalyst dominates for initiation of polymerization. Without any significance loss of structural morphology and catalytic activity, ZIF‐8 can easily be recycled for further uses. ZIF‐8 exhibits superior activities for the synthesis of high molecular weight PMMA compared to the heterogeneous catalysts mentioned earlier.
Hand made solar cells from chlorophyll for teaching in high school energy education (2020)

High school students show more motivation to learn new concepts when these are taken from activities that mimic real life. We report an easy methodology based on the fabrication of handmade solar cells to produce clean energy from chlorophyll a (chl-a) extracted from the leaves of Diacol Capiro potato. Our findings show that there is no proportionality between the chl-a concentration and the output voltage. The results also indicated that nickel-silver electrodes were the most efficient among other tested electrode pairs, yielding a maximum voltage value of 1.006 V from an individual cell. Therefore, a low-cost natural dye as chlorophyll can be used as light-harvesting material. As a result, 90% of the students learned basic techniques and applications of visible light for characterisations and 85% understood the electric potential in an electrochemical cell.
Preparation and characterization of polymer-bound polydentate amines (1979)

Synthetic procedures for attaching multidentate amines to organic polymers are described, to produce materials which may be used for the preparation of a wide variety of macrocyclic and chelating ligands that can be covalently attached to polymers; the reaction to produce Schiff base chelates is described and a series of covalently attached metal complexes have been prepared and identified.
Metallic Nanobrushes Made using Ambient Droplet Sprays (2016)

An ambient solution-state method for making uniform nanobrushes composed of oriented 1D silver nanowires (NWs) with aspect ratios of 10(2) -10(4) is reported. These structures are grown over cm(2) areas on conducting surfaces. Assemblies of NWs form uniform nanobrush structures, which can capture micrometer-sized objects, such as bacteria and particulate matter. Variation in composition produces unique structures with catalytic properties.
In vitro selection of an XNA aptamer capable of small-molecule recognition (2018)

Despite advances in XNA evolution, the binding capabilities of artificial genetic polymers are currently limited to protein targets. Here, we describe the expansion of in vitro evolution techniques to enable selection of threose nucleic acid (TNA) aptamers to ochratoxin A (OTA). This research establishes the first example of an XNA aptamer of any kind to be evolved having affinity to a small-molecule target. Selection experiments against OTA yielded aptamers having affinities in the mid nanomolar range; with the best binders possessing KD values comparable to or better than those of the best previously reported DNA aptamer to OTA. Importantly, the TNA can be incubated in 50% human blood serum for seven days and retain binding to OTA with only a minor change in affinity, while the DNA aptamer is completely degraded and loses all capacity to bind the target. This not only establishes the remarkable biostability of the TNA aptamer, but also its high level of selectivity, as it is capable of binding OTA in a large background of competing biomolecules. Together, this research demonstrates that refining methods for in vitro evolution of XNA can enable the selection of aptamers to a broad range of increasingly challenging target molecules.
Zum altpersischen Hya (1999)

Dans cet article, l'auteur fait une étude du pronom relatif vieux-perse hya. Surtout la prononciation ancienne de ce pronom est discutée.
QUATUOR : une application des modeles dynamiques en transport au reseau de transport Ile-de-France. Note de synthese (2002)

L'ensemble du projet QUATUOR a ete mene sur une duree de 3 ans et a donne lieu a deux rapports annuels et un rapport final. L'objet de cette note de synthese est de mettre l'accent sur les fondements theoriques sous-jacents a la modelisation dynamique retenue, de presenter les outils de simulation utilises et de rendre compte des resultats de calage des logiciels aux donnees disponibles. Dans le chapitre 1, sont presentes les fondements theoriques des modeles dynamiques presents dans le cadre de l'economie des transports et developpes depuis environ 30 ans. Le chapitre 2 decrit un outil de planification dynamique, le logiciel de simulation METROPOLIS. Les donnees necessaires, les resultats calcules par le simulateur et la methodologie de lecture de certains resultats sont notamment precises. Les auteurs, dans le chapitre 3, resument leurs travaux de calage du modele de planification dynamique, METROPOLIS, aux donnees communiquees par l'IAURIF et la DREIF. En ajustant deux parametres, il leur a ete possible de rendre compte de maniere satisfaisante des donnees de terrain qui leur ont ete fournies. Une synthese de resultats et des enseignements de l'etude ainsi qu'une liste des perspectives de recherche sont presentees dans les conclusions generales.
A microcomputer-based demonstration system for musical acoustics education (1987)

While an ideal musical acoustics education laboratory would include an extensive collection of electronic measurement, recording, and display equipment together with appropriate space, staff, and maintenance staff to support student use, this situation is seldom possible because of limited funds. Our solution has been to configure and program a microcomputer (IBM PC AT) to serve as a mobile multifunction demonstration station. The station is capable of high-resolution color display, stereo audio/digital input/output, hardware FFT analysis, and MIDI input/output. Thus far, the following demonstrations have been completed: (1) animated display simulation of wave propagation on strings and within pipes; (2) waveform/spectrum display and sound synthesis from given Fourier amplitudes and phases; (3) single frame spectrum analysis of audio signals; (4) display simulation of modes on square and circular vibrating membranes; and (5) sound synthesis comparison of just, Pythagorean, and equal-tempered scales. One advantage of this microcomputer-based system is that new demonstrations can be incorporated easily by writing new programs for the existing hardware. [Work supported by an IBM grant to UIUC.]
NGF induces pulmonary arterial hyperreactivity through connexin 43 increased expression (2020)

We have shown that the nerve growth factor NGF plays a pathophysiological role in pulmonary hypertension by promoting pulmonary arterial (PA) inflammation, remodelling and hyperreactivity. The aim of this study was to determine the mechanisms of NGF-induced PA hyperreactivity, focusing on Connexin 43 (Cx43), a gap junction protein essential for vascular reactivity. Expression of NGF and its TrkA receptor were evaluated by Western blotting in human PA smooth muscle cells (hPASMC) from controls or from patients suffering from idiopathic pulmonary arterial hypertension (IPAH). Cx43 expression and localisation were evaluated by Western blotting, immunofluorescence and cell surface biotinylation, after NGF treatment. Gap junction activity was assessed by FRAP microscopy. Contractions of rat PA were induced by phenylephrine (PHE), with or without NGF. The role of Cx43 in NGF-induced rat PA hyperreactivity was evaluated by use of 43Gap26, a Cx43 blocking peptide, or by an anti-Cx43 siRNA. NGF and TrkA expression were increased in hPASMC from IPAH patients compared to controls. NGF increased Cx43 expression in hPASMC, with a higher sensitivity in IPAH cells compared to controls cells. This increase was abolished with K252a, a TrkA kinase inhibitor. Cx43 plasma membrane localisation and GAP junction activity were also increased after NGF treatment. NGF-induced PA hyperreactivity to PHE was inhibited after ex vivo treatment with 43Gap26 or after in vivo treatment with Cx43 siRNA. In conclusion, NGF pathway is upregulated in IPAH cells. NGF increases Cx43 PA expression through TrkA receptor. Cx43 increased expression at plasma membrane upregulates GAP junction activity, thus promoting PA hyperreactivity.
Racial Disparities Across Provider Specialties in Opioid Prescriptions Dispensed to Medicaid Beneficiaries with Chronic Noncancer Pain (2014)

Our findings suggest that, in our study population, black beneficiaries with CNCP are less likely than whites to fill prescriptions for opioid analgesics as a function of their provider's specialty. Although race-based differences in patients filling opioid prescriptions have been noted in previous studies, this is the first study that clearly demonstrates these disparities by provider specialty.
Hypertension in Unilaterally Nephrectomized Rats Induced by Single–Kidney Transfection with Angiotensinogen cDNA (1999)

Plasmid expression vectors containing angiotensinogen (ATG) cDNA were complexed to cationic liposomes and injected into the renal artery of unilaterally nephrectomized rats to evaluate the effect of intrarenal ATG cDNA on arterial blood pressure and the renin-angiotensin system. Systolic blood pressures measured by tail cuff on days 12, 16, and 18 after transfection were significantly higher in rats that received ATG cDNA than in control rats that received the lac Z reporter gene. Plasma renin activity and plasma ATG concentration were unchanged. These results provide direct evidence that the availability of intrarenal ATG may be instrumental in the development of systemic hypertension.
Synthesis of Diphenyl Ether-4, 4&prime;-diacetic Acid (1950)

Application of formaline and HCl-gas in glacial AcOH solution of diphenyl ether under the presence of ZnCl2 gives 4, 4′-dichloromethyl-diphenyl ether, m.p. 64°, white, scaly crystals with the formula of C14H12OCl2. This gives a methyl ester of m.p. 154° by methylation of the acid obtained by oxidation with KMnO4. This compound was determined by the mixed fusion with dimethyl diphenyl ether-4, 4′-dicarboxylate. This proves the fact that the chloro-methylation occurs in the 4, 4′-position of diphenyl ether nucleus. This dichloromethyl derivative can be led to dicyanomethyl derivative and then decomposed by 50% H2SO4 to 4, 4′-diphenyl ether-4, 4′-diacetic acid, m.p. 207-208°, which gives a formula of C16H14O5 by analysis and corresponds to the objective substance.
Sampling Criterion for EMC Near Field Measurements (2012)

An alternative, quasi-empirical sampling criterion for EMC near field measurements intended for close coupling investigations is proposed. The criterion is based on maximum error caused by sub-optimal sampling of near fields in the vicinity of an elementary dipole, which is suggested as a worst-case representative of a signal trace on a typical printed circuit board. It has been found that the sampling density derived in this way is in fact very similar to that given by the antenna near field sampling theorem, if an error less than 1 dB is required. The principal advantage of the proposed formulation is its parametrization with respect to the desired<br/>maximum error in measurements. This allows the engineer performing the near field scan to choose a suitable compromise between accuracy and measurement time.
ChemInform Abstract: Squaraine Dyes in PDT: From Basic Design to in vivo Demonstration (2012)

Abstract Review: 58 refs.
MiR-200c sensitizes Olaparib-resistant ovarian cancer cells by targeting Neuropilin 1 (2020)

These data demonstrate that miR-200c significantly enhanced the anti-cancer efficacy of Olaparib in drug-resistant OC cells. Thus, the combination of Olaparib with miRNA-based therapy may represent a promising treatment for drug resistant OC, and our data may help in designing novel precision medicine trials for optimizing the clinical use of PARPi.
Methylation of Specific Microrna Genes In MLL-Rearranged Infant Acute Lymphoblastic Leukemia: - Major Matters at a Micro Scale - (2010)

Abstract Abstract 2483 MLL-rearranged Acute Lymphoblastic Leukemia (ALL) in infants (&lt;1 year) represents one of the most aggressive types of childhood leukemia. In order to develop more suitable treatment strategies, a firm understanding of the biology underlying this disease is of utmost importance. MLL-rearranged ALL displays a unique gene expression profile, partly explained by erroneous histone modifications. We recently showed that t (4;11)-positive infant ALL is also characterized by pronounced promoter CpG hypermethylation. Here we investigated whether this widespread hypermethylation also affected microRNA (miRNA) expression. We performed CpG methylation analyses at 122 miRNA loci using Differential Methylation Hybridization (DMH), and miRNA expression analyses using quantitative real-time PCR on primary t (4;11)-positive infant ALL samples (n= 22) and normal pediatric bone marrows (n= 7). We identified 11 miRNAs that were markedly down-regulated in t (4;11)-positive infant ALL as a consequence of CpG hypermethylation. Seven of these miRNAs were re-activated after exposure to the de-methylating agent Zebularine. Interestingly, 5 of these miRNAs had already been associated either with the MLL gene or with leukemic MLL fusions. For one of the remaining miRNAs, i.e. miR-152, we demonstrate that high degrees of methylation strongly correlate with a poor clinical outcome. Moreover, we identified MLL and DNA methyltransferase 1 (DNMT1) as potential target genes for miR-152. Thus, genome-wide DNA methylation in MLL-rearranged infant ALL not only inactivates numerous protein-coding genes, but also affects several miRNA genes. While inhibition of methylation by Zebularine to certain extents re-activates gene expression, re-activation of miRNAs by this agent restores the suppression of associated target genes. As demethylating agents exert their functions by covalently trapping DNMT1 to the DNA, re-activation of miR-152 by Zebularine further supports demethylation by targeting DNMT1 expression. In summary, our data demonstrates an important role for genome-wide DNA methylation in suppressing miRNA expression and provides additional grounds to initiate efficacy testing of demethylating agents in MLL-rearranged ALL in vivo. Disclosures: No relevant conflicts of interest to declare.
Direct fabrication of integrated 3D epitaxial functional transition metal oxide nanostructures using extremely small hollow nanopillar nano-imprint metal masks (2011)

A novel nanofabrication technique is developed for functional oxides. Combining nano-imprint lithography, sidewall-etching and sidewall-deposition processes enables us to prepare Mo hollow nanopillar masks with 100 and 60 nm window sizes, which is smaller than the original nano-imprint mold size of 250 nm. Using this Mo nanomask, extremely small epitaxial ferromagnetic oxide (Fe(2.5)Mn(0.5)O(4)) nanostructures can be directly grown on sapphire substrates at the deposition temperature of 350 °C in a pulsed laser deposition (PLD) process.
Use of the noninvasive components of the mayo score to assess clinical response in Ulcerative Colitis (2008)

The partial Mayo score and the 6-point score composed solely of the stool frequency and bleeding components performed as well as the full Mayo score to identify patient perceived clinical response.
Algorithms for Minimization Without Derivatives (1974)

This monograph describes and analyzes some practical methods for finding approximate zeros and minima of functions.
Solid-Phase Extraction and Large-Volume Sample Stacking-Capillary Electrophoresis for Determination of Tetracycline Residues in Milk (2018)

Solid-phase extraction in combination with large-volume sample stacking-capillary electrophoresis (SPE-LVSS-CE) was applied to measure chlortetracycline, doxycycline, oxytetracycline, and tetracycline in milk samples. Under optimal conditions, the proposed method had a linear range of 29 to 200 <i>µ</i>g·L<sup>-1</sup>, with limits of detection ranging from 18.6 to 23.8 <i>µ</i>g·L<sup>-1</sup> with inter- and intraday repeatabilities < 10% (as a relative standard deviation) in all cases. The enrichment factors obtained were from 50.33 to 70.85 for all the TCs compared with a conventional capillary zone electrophoresis (CZE). This method is adequate to analyze tetracyclines below the most restrictive established maximum residue limits. The proposed method was employed in the analysis of 15 milk samples from different brands. Two of the tested samples were positive for the presence of oxytetracycline with concentrations of 95 and 126 <i>µ</i>g·L<sup>-1</sup>. SPE-LVSS-CE is a robust, easy, and efficient strategy for online preconcentration of tetracycline residues in complex matrices.
Linearly polarized electroluminescence from ionic iridium complex-based metallomesogens: the effect of aliphatic-chain on their photophysical properties (2018)

Clearly polarized electroluminescence was obtained from ionic iridium complex-based metallomesogens.
<title>Security design of valuable documents and products</title> (1996)

A method of security design is presented, founded on a systematic seven step approach: (1) drafting a security policy, (2) a list of requirements, (3) a security scheme, and (4) a fraud-risk analysis. Based on these documents: (5) the security measures can be selected, (6) and implemented, (7) to result in a security product. Simulation and/or experiments are required to assess the relevant properties of the design or product. The actual evaluation consists of comparing these properties with the requirements. Subsequently weak and strong points, and possible paths of attack will be established. In case the evaluation reveals a considerable mismatch between requirements and characteristics, the design cycle has to be passed through again and either the requirements must be adapted, or the design, or both. This procedure is repeated until the remaining mismatch between requirements and design properties becomes acceptable. It is paramount that an evaluation is not postponed until the final stage of product realization, but is carried out in the early phases of the project. In fact it is beneficial if all seven step of the design are the subject of an evaluation. Some design considerations for optically variable devices are discussed.
Chemogenetic Isolation Reveals Synaptic Contribution of δ GABAAReceptors in Mouse Dentate Granule Neurons (2018)

Two major GABA<sub>A</sub> receptor classes mediate ionotropic GABA signaling, those containing a δ subunit and those with a γ2 subunit. The classical viewpoint equates γ2-containing receptors with IPSCs and δ-containing receptors with tonic inhibition because of differences in receptor localization, but significant questions remain because the populations cannot be pharmacologically separated. We removed this barrier using gene editing to confer a point mutation on the δ subunit in mice, rendering receptors containing the subunit picrotoxin resistant. By pharmacologically isolating δ-containing receptors, our results demonstrate their contribution to IPSCs in dentate granule neurons and weaker contributions to thalamocortical IPSCs. Despite documented extrasynaptic localization, we found that receptor localization does not preclude participation in isolated IPSCs, including mIPSCs. Further, phasic inhibition from δ subunit-containing receptors strongly inhibited summation of EPSPs, whereas tonic activity had little impact. In addition to any role that δ-containing receptors may play in canonical tonic inhibition, our results highlight a previously underestimated contribution of δ-containing receptors to phasic inhibition.<b>SIGNIFICANCE STATEMENT</b> GABA<sub>A</sub> receptors play key roles in transient and tonic inhibition. The prevailing view suggests that synaptic γ2-containing GABA<sub>A</sub> receptors drive phasic inhibition, whereas extrasynaptic δ-containing receptors mediate tonic inhibition. To re-evaluate the impact of δ receptors, we took a chemogenetic approach that offers a sensitive method to probe the synaptic contribution of δ-containing receptors. Our results reveal that localization does not strongly limit the contribution of δ receptors to IPSCs and that δ receptors make an unanticipated robust contribution to phasic inhibition.