gebhart/patrepeval huggingface dataset:
PET/CT Gating Workflow Efficiency Improvements using Continuous Bed Motion Imaging Techniques. (2015)

2628 Objectives Continuous Bed Motion (CBM) technology has created a new way of running PET/CT scans. There are many workflow improvements using CBM compared to tradiational Step and Shoot (SS) imaging. One key improvement is reduced time for gated protocol setup and imaging enabling more routine use of respiratory motion correction. This study assesses the impact of improvements using CBM vs. traditional SS techniques. Methods Protocols were setup and all patients imaged using a Siemens Biograph mCT with FlowMotion CBM technology. To evaluate improvements in gating, 2 respiratory gated protocols of the lungs were created, one using SS and one CBM. The total scan time for each PET protocol were recorded and compared. Technologists were asked to set up a respiratory gated protocol using SS and CBM protocols. Protocol setup time was recorded and the number of mouse clicks counted during set up. Results Total scan time for CBM respiratory gated protocols were less than those for similar SS protocols. The average reduction of scan time when using CBM compared to SS was 23% and was statistically significant (p 0.05). Average scan time and setup savings of 2.54 minutes was observed when using CBM. Conclusions CBM respiratory gated protocols are more efficient than SS respiratory gated protocols. When using CBM to create a gated respiratory image an exact range size can be selected to cover the area of interest instead of being limited to ranges of multiples of beds, which reduces the scan time of the gated image allowing more routine use. Patient Protocol setup times are decreased by using CBM vs. SS. The timely manner of CBM gating allows for disease specific imaging without interfering with clinical workflow. Research Support Funding for this research was provided by departmental funds of the Molecular Imaging and Translationals Research Program in the Graduate School of Medicine at the University of Tennessee.
Ictus isquémico como complicación del cateterismo cardíaco. Características clínicas, radiológicas y evolutivas e implicaciones terapéuticas (2019)

Post-catheterisation stroke is initially less severe, and presents more often as transient ischaemic attack and less frequently as proximal artery occlusion. Most post-catheterisation strokes are not treated with reperfusion; in case of artery occlusion, mechanical thrombectomy is the preferred treatment.
The phenomenology of dielectric breakdown in thin silicon dioxide films: Al cathodes and p-type Si anodes (1989)

Various aspects of the phenomenology of dielectric breakdown in Al-SiO2-p-Si metal-oxide-semiconductor planar capacitor structures have been investigated.The different types of breakdown events and their distributions are discussed in light of breakdown data from constant current stress tests and linearly ramped voltage tests with variable ramp rates. Many tests were performed on a wide variety of samples using Weibull-type distribution functions in analyzing the data. Of special interest was the influence of substrate parameters, such as oxygen concentration, surface transition-metal contamination, surface roughness, and the relatively simple surface defects which can form during a single oxidation treatment. Using very careful methods, three general types or ‘‘modes’’ of breakdown distribution are observed, a mode being defined as a subset of the complete distribution exhibiting the same or similar time and field parameters in the Weibull distribution. Two of the distinct modes are related to distributed ‘‘weak spots.’’ The third is apparently ‘‘intrinsic.’’ Implications for device reliability are considered. The origin and elimination of the distributed weak spot modes is discussed as are details of the intrinsic mode.
SQL-Rank: A Listwise Approach to Collaborative Ranking (2018)

In this paper, we propose a listwise approach for constructing user-specific rankings in recommendation systems in a collaborative fashion. We contrast the listwise approach to previous pointwise and pairwise approaches, which are based on treating either each rating or each pairwise comparison as an independent instance respectively. By extending the work of (Cao et al. 2007), we cast listwise collaborative ranking as maximum likelihood under a permutation model which applies probability mass to permutations based on a low rank latent score matrix. We present a novel algorithm called SQL-Rank, which can accommodate ties and missing data and can run in linear time. We develop a theoretical framework for analyzing listwise ranking methods based on a novel representation theory for the permutation model. Applying this framework to collaborative ranking, we derive asymptotic statistical rates as the number of users and items grow together. We conclude by demonstrating that our SQL-Rank method often outperforms current state-of-the-art algorithms for implicit feedback such as Weighted-MF and BPR and achieve favorable results when compared to explicit feedback algorithms such as matrix factorization and collaborative ranking.
Preemptive cardiac resynchronization therapy to prevent cardiac arrest in peripartum cardiomyopathy: a case report (2020)

Select patients with peripartum cardiomyopathy are candidates for implantable cardioverter-defibrillator (ICD) or cardiac resynchronization therapy (CRT) due to the increased risk for life threatening arrhythmias and sudden death. We present a case of peripartum cardiomyopathy awaiting CRT placement who suffered cardiac arrest during the surgical dilation and curettage (D&amp;C) procedure for pregnancy termination.
Efficient Algorithms for Fixed-Rate (1994)

In quantisation of any source with a nonuniform probability density function, the entropy coding of the quantizer output can result in a substantial decrease in bit rate. A straight-forward entropy coding scheme presents us with the problem of the variable data rate. A solution in a space of dimensionality N is to select a subset of elements in the N-fold cartesian product of a scalar quantiaer and represent them with codcworda of the same length. A reasonable rule is to select the N-fold symbols of the highest For a memoryless source, this is equivalent to selecting the N-fold symbols with the lowest additiveself-information. The search/addressingof this scheme can no longer be achieved independently along the oncdimensional subspaces. In the case of a memoryless source, the selected subset has a high degree of structure which can be used to substantially decrease the complexity. In this work, a dynamic prog&nmbq approach is used to exploit this structure. We build our recursive structure required for the dynamic programming in a hierarchy of stages. This results in several benefits over the conventional trellis-based approaches. Using this structure, we develop efficient rules (based on aggregating the states) to substantially reduce the search/addredsing complexities while keeping the degradation negligible.
Giant effective pyroelectric coefficients from graded ferroelectric devices (1998)

Effective pyroelectric coefficients as large as 5 μC/cm2 °C, with peak responsivities at approximately 50 °C, were obtained from compositionally graded barium strontium titanate ferroelectric thin film devices formed on silicon using unbalanced magnetron sputter deposition. These effective pyroelectric coefficients are nearly two orders of magnitude larger than those observed from conventional pyroelectric thin film ferroelectric detectors.
Recurrent Neural Networks Biomass Observer for Anaerobic Processes (2008)

In this paper, a recurrent neural networks observer for anaerobic processes is proposed; the main objective is to estimate biomass, in a completely stirred tank reactor. The neural network is trained with an extended Kalman filter algorithm. The applicability of the proposed observer is verified via simulations.
Mammalian Notum induces the release of glypicans and other GPI-anchored proteins from the cell surface (2008)

Glypicans are heparan sulfate proteoglycans that are attached to the cell surface by a GPI (glycosylphosphatidylinositol)anchor. Glypicans regulate the activity of Wnts, Hedgehogs,bone morphogenetic proteins and fibroblast growth factors. In the particular case of Wnts, it has been proposed that GPI-anchored glypicans stimulate Wnt signalling by facilitating and/or stabilizing the interaction between Wnts and their cell surface receptors. On the other hand, when glypicans are secreted to the extracellular environment, they can act as competitive inhibitors of Wnt. Genetic screens in Drosophila have recently identified a novel inhibitor of Wnt signalling named Notum. The Wnt inhibiting activity of Notum was associated with its ability to release Dlp [Dally (Division abnormally delayed)-like protein; a Drosophila glypican] from the cell surface by cleaving the GPI anchor. Because these studies showed that the other Drosophila glypican Dally was not released from the cell surface by Notum,it remains unclear whether this enzyme is able to cleave glypicans from mammalian cells. Furthermore, it is also not known whether Notum cleaves GPI-anchored proteins that are not members of the glypican family. Here, we show that mammalian Notum can cleave several mammalian glypicans. Moreover, we demonstrate that Notum is able to release GPI-anchored proteins other than glypicans. Another important finding of the present study is that,unlike GPI-phospholipase D, the other mammalian enzyme that cleaves GPI-anchored proteins, Notum is active in the extracellular environment. Finally, by using a cellular system in which GPC3 (glypican-3) stimulates Wnt signalling, we show that Notum can act as a negative regulator of this growth factor.
Autonomic Elasticity Control for Multi-Server Queues Under Generic Workload Surges in Cloud Environments (2020)

Cloud computing environments and Internet datacenters consist of a multitude of servers that process user requests. Performance and scalability can suffer greatly when the workload surges to levels that cause a system to become unstable (i.e., when the arrival rate of requests exceeds the system’s capacity to process them). This article presents a detailed design and evaluation of an autonomic elasticity controller for surges of any shape. This controller uses an analytical model, derived by the authors, of a single-queue multiple-server system (G/G/c) subject to workload surges that cause the system to become unstable during finite time intervals. The controller is evaluated through extensive simulations and by using publicly available Google traces. The controller is further extended to take into account VM startup delays. The article also illustrates how fudge factors can be used to more aggressively react to surges at the expense of additional resources. Finally, our controller is compared with a hypothetical oracle controller that knows the exact shape of the surge when it starts to occur.
IC‐P‐128: Progressive white matter abnormalities in autosomal dominant Alzheimer's disease: Results of the DIAN study (2012)

DIAN (Dominantly Inherited Alzheimer's Network) is an international longitudinal study of autosomal dominant Alzheimer's disease, including individuals affected with, or at risk for, AD. In late onset AD it is often difficult to separate white matter disease associated with aging and diseases of aging (hypertension, diabetes, etc) from that of AD. In this young cohort, we quantified WM pathology using volumetric MRI and diffusion tensor imaging (DTI) in order to evaluate WM disease in ADAD. 71 participants from the DIAN study underwent DTI. Participants were classified into four groups based upon mutation (M+ and M-) and dementia status (CDR, Table 1). DTI was acquired using a 64 direction sequence at 3T. Image analysis was conducted with Tract Based Spatial Statistics (TBSS), a part of FSL. Group-level differences were assessed with a general linear model controlling for age, gender, and education and corrected for multiple comparisons using Threshold-Free Cluster Enhancement. Volumetric T1 (MPRAGE) studies were processed with FreeSurfer to generate white matter volumes. White matter volumes decrease with carrier status and progressive dementia (Figure 1). Associated loss of fractional anisotropy (FA, Figure 2) and elevated mean diffusivity (MD, not shown) are widespread. Periventricular white matter is particularly involved at very mild (CDR 0.5) and mild (CDR 1.0) dementia (Figure 2). These findings support the hypothesis that widespread white matter abnormalities are associated with dementia in ADAD, and that these abnormalities precede the development of dementia. Total white matter volume was ascertained using FreeSurfer. Loss of white matter is present in carriers in the asymptomatic phase of the disease (CDR 0), and progresses as CDR increases. Significance was assessed using a one-tailed t-test, adjusted for head size and with age, gender and education as covariates. P values are<0.05 except in the CDR 0.5 vs CDR CDR> = 1 comparison.
SYNTHESIS OF 6-DIMETHYLAMINO-4,4-DIPHENYLHEPTANE AND OTHER COMPOUNDS RELATED TO METHADONE (1954)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSYNTHESIS OF 6-DIMETHYLAMINO-4,4-DIPHENYLHEPTANE AND OTHER COMPOUNDS RELATED TO METHADONET. D. PERRINE and EVERETTE L. MAYCite this: J. Org. Chem. 1954, 19, 5, 773–779Publication Date (Print):May 1, 1954Publication History Published online1 May 2002Published inissue 1 May 1954https://pubs.acs.org/doi/10.1021/jo01370a012https://doi.org/10.1021/jo01370a012research-articleACS PublicationsRequest reuse permissionsArticle Views129Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Structural Representation: Reducing Multi-Modal Image Registration to Mono-Modal Problem (2015)

&lt;p&gt;Registration of multi-modal images has been a challenging task&lt;br /&gt;due to the complex intensity relationship between images. The&lt;br /&gt;standard multi-modal approach tends to use sophisticated similarity&lt;br /&gt;measures, such as mutual information, to assess the accuracy&lt;br /&gt;of the alignment. Employing such measures imply the increase in&lt;br /&gt;the computational time and complexity, and makes it highly difficult&lt;br /&gt;for the optimization process to converge. The presented registration&lt;br /&gt;method works based on structural representations of images&lt;br /&gt;captured from different modalities, in order to convert the multimodal&lt;br /&gt;problem into a mono-modal one. Two different representation&lt;br /&gt;methods are presented. One is based on a combination of&lt;br /&gt;phase congruency and gradient information of the input images,&lt;br /&gt;and the other utilizes a modified version of entropy images in a&lt;br /&gt;patch-based manner. Sample results are illustrated based on experiments&lt;br /&gt;performed on brain images from different modalities.&lt;/p&gt;
1.7 μm band optical fiber amplifier (2014)

We report the first experimental realization of a 1.7 μm band optical fiber amplifier by using a Tm3+-Tb3+-doped fiber as an active fiber, and 1.21μm LD pumping. The maximum signal gain of 22.5 dB and a 3 dB down output signal power of -1 dBm have been achieved at the signal wavelength around 1700 nm with a launched pump power of 277 mW. The 3 dB down amplification bandwidth was 31 nm. Noise figure was lower than 6.2 dB in the signal wavelength region of less than 1700 nm.
Autoantibodies to epithelial cells in patients on long-term therapy with leucocyte-derived interferon-alpha (IFN-α) (1990)

During routine screening for anti-nuclear antibodies, using rat liver tissue as substrate, a reactivity against bile duct epithelium was observed in sera from carcinoid tumour patients given human leucocyte-derived IFN-alpha (HuLe IFN-alpha). In a retrospective study, initiated by this observation, the development of serum antibodies to bile duct epithelium was observed in nine out of 12 patients with carcinoid tumours and in three out of 14 patients with hairy-cell leukaemia during their treatment with HuLe IFN-alpha. However, no bile duct reactivity was observed in sera from carcinoid or hairy-cell leukaemia in patients given recombinant IFN-alpha. When analysing the reactivity of positive sera against a panel of rat and human tissues, a uniform reactivity was observed against simple epithelial cells lining the gastrointestinal tract, pancreatic secretory ducts, fallopian tube, kidney tubuli, mesothelium and also against carcinoid tumour cells. The mechanisms promoting autoreactivity against this simple epithelial cell autoantigen is so far unknown. The cytoplasmic as well as the restricted staining pattern of simple epithelial cells may indicate autoreactivity against certain cytoskeletal intermediate filaments, such as cytokeratin 19, 18 and 8, known to be exclusively present in simple epithelial cells and tumours derived from them.
Pioglitazone attenuates hypertension and inhibits growth of renal arteriolar smooth muscle in rats (1993)

Hypertension is frequently associated with insulin resistance. We evaluated the effects of pioglitazone, an agent that increases insulin sensitivity, on the development of hypertension in the Dahl salt-sensitive (Dahl-S) rat and in the one-kidney, one-clip Sprague-Dawley rat. We also evaluated the effects of pioglitazone on growth of cultured preglomerular renal arteriolar smooth muscle cells. In Dahl-S rats fed a 3% NaCl diet, tail systolic blood pressures and direct arterial pressures were lower (P < 0.05) in pioglitazone-treated (20 mg/kg daily by gavage for 3 wk) than in control rats (n = 10 rats/group). In one-kidney, one-clip Sprague-Dawley rats, systolic blood pressures were also lower in pioglitazone-treated animals (P < 0.0001). In vitro, proliferation of arteriolar smooth muscle cells was stimulated (P < 0.01) by insulin, epidermal growth factor (EGF), and fetal calf serum (FCS); pioglitazone (5 microM) reversibly inhibited (P < 0.01) insulin-, EGF-, and FCS-induced proliferation. Pioglitazone (0.01-100 microM) also inhibited insulin- (1 mU/ml), EGF- (100 ng/ml), and 5% FCS-induced [3H]thymidine incorporation in a concentration-dependent manner (P < 0.01). Thus pioglitazone attenuated the development of hypertension in the Dahl-S rat and the one-kidney, one-clip rat. The ability of pioglitazone to inhibit growth of vascular smooth muscle may contribute to its hypotensive effect.
APPLICATION OF NEUROTROPHIC FACTORS BDNF AND NT-3 IN CELL THERAPY OF EXPERIMENTAL POSTTRAUMATIC SPINAL CORD CYSTS (2021)

The experimental post-traumatic spinal cord cysts were modeled. It has been shown that NT-3 enhances the effectiveness of the use of human olfactory ensheathing cells in the treatment of experimental spinal cord cysts.
Chemical Titration and Transient Kinetic Studies of Site Requirements in Mo2C-Catalyzed Vapor Phase Anisole Hydrodeoxygenation (2015)

The turnover frequency (TOF) of benzene synthesis from vapor phase anisole hydrodeoxygenation (HDO), estimated via in situ CO titration, was found to be invariant (1.1 ± 0.3 × 10–3 s–1) over molybdenum carbide (Mo2C) catalysts with varying CO chemisorption uptakes (∼70 to ∼260 μmol g–1, measured ex situ at 323 K). Accumulation of oxygen (∼0.29 monolayer) over Mo2C catalysts was determined by an oxygen mass balance during the transient of anisole HDO at 423 K under ambient pressure (H2/anisole molar ratio ∼ 110). Similar product selectivity, apparent activation energy, and TOF of benzene synthesis for an oxygen treated (with oxygen incorporation: O/Mobulk (molar ratio) = 0.075) and freshly prepared Mo2C catalysts (no exposure to air prior to kinetic measurements) demonstrate that the effect of oxygen at these low concentrations is solely to reduce the number of active sites for anisole HDO, resulting in a lower (∼3 times) benzene synthesis rate per gram of catalyst for the oxygen-modified material. The observed benzene synthesis rates per CO chemisorption site for bulk molybdenum oxide (MoOx) catalysts were found to be ∼10 times lower than those for Mo2C catalysts, suggesting that bulk molybdenum oxide phases are not associated with the dominant active sites for anisole HDO at 423 K under ambient pressure.
First-principles study of electronic, vibrational, elastic, and magnetic properties of FeF2as a function of pressure (2012)

We report systematic ab initio calculations of the electronic band structure, phonon dispersion relation, and the structural characterization of FeF${}_{2}$ in the rutile ($P{4}_{2}/mnm$) structure as well as in several high-pressure phases by means of the generalized gradient approximation (GGA)+U approximation. Using the phonon dispersion relations, we calculated the Gibbs free energy and evaluated the phase transitions at 300 K, at which most experimental measurements are performed. Calculated Raman and infrared vibrational modes, lattice parameters, and electronic structure for all considered crystalline structures are compared with available experimental data. Our calculations show that at 5.33 GPa, the FeF${}_{2}$ undergoes a second-order proper ferroelastic phase transition, rutile $\ensuremath{\rightarrow}$ CaCl${}_{2}$-type structure. This result is supported by the softening of the elastic shear module ${C}_{s}$ in the rutile phase, the softening (hardening) of the ${B}_{1g}$ (${A}_{g}$) Raman active mode in the rutile (CaCl${}_{2}$-type) structure near the transition pressure, and the decrease of the square of the spontaneous strain ${e}_{ss}$ from the CaCl${}_{2}$-type structure. This demonstrates that the rutile $\ensuremath{\rightarrow}$ CaCl${}_{2}$-type phase transition is driven by the coupling between the Raman active ${B}_{1g}$ mode and shear modulus ${C}_{s}$. At 8.22 GPa, the CaCl${}_{2}$-type structure undergoes a first-order phase transition to the $Pbca$ phase, a distorted fcc $Pa\overline{3}$ phase with a volume reduction of $\ensuremath{\Delta}V\ensuremath{\approx}7%$, as reported in experiments. Upon further increase of the pressure, the $Pbca$ phase transforms to a $Fmmm$ phase othorhombic center-type structure at $\ensuremath{\sim}$20.38 GPa, with $\ensuremath{\Delta}V\ensuremath{\approx}2.5%$. Finally, at 25.05 GPa, there is a phase transition to the orthorhombic cotunnite structure ($Pnma$ space group), with $\ensuremath{\Delta}V\ensuremath{\approx}5.8%$, which is stable up to 45 GPa, the largest considered pressure. The coordination number for the Fe ion in each phase is 6, 6, 6, 8, and 9 for rutile, CaCl${}_{2}$-type, $Pbca$, $Fmmm$, and cotunnite structures, respectively. The evolution of the band gap, phonon frequencies, and magnetic moment of Fe ion as a function of the applied pressure is reported for all studied phases. The exchange constants ${J}_{1}$, ${J}_{2}$, and ${J}_{3}$, calculated for rutile and the lowest Gibbs free-energy high-pressure phases, are reported.