gebhart/patrepeval huggingface dataset:
FREQENCY COMPENSATION SCHEME USINGPOLAR COORDINATE FUNCTIONFOR BURSTTRANSMISSIONWIRELESSMODEM (2006)

Newfrequency compensation circuit hasbeenproposed using preamble symbols andsomepilot symbols. Theproposed circuit hadaperformance ofcompensation withtheoffset of 50ppmat2.4GHzcarrier. Initial phase detection andcourse frequency compensation was achieved from16-symbol preamble. Minimummeansquareschemewasusedfor evaluation ofinitial phaseandfrequency error fromphase information ofpreamble symbols. Accurate compensation of residual frequency offset wasoperated fromthephase information ofpilot symbols inserted placed ininformation payload. Wireless packet modemhasbeenimplemented on field programmable gatearray (FPGA).Conversion from rectangle coordinates function topolar coordinate function was employed forsimplesignal processing. Division calculator bybitshifts andlookup table byreadonly memory (ROM)wereusedforcompact circuit design. Degradation of measured BER fromideal performance wasconfirmed tobe less than2.5dB.
Time-resolved combination of the Mueller–Stokes and Jones calculus for the optimization of a twisted-nematic spatial-light modulator (2015)

Twisted-nematic spatial light modulators show a coupling between phase and intensity modulation. We present quick and simple methods that exhibit a minimum impact of measurement errors for characterizing the modulator&#x2019;s optical properties. We utilize a time-resolved combination of the Mueller&#x2013;Stokes and Jones calculus to adapt the polarization configuration in the optical system for phase-only modulation. Furthermore, we investigate the flicker-effect and propose a novel method which completely compensates its temporal influence in applications with fast detectors. Although we apply our methods to a HOLOEYE LC-R 2500 they can be generalized for the application with any liquid-crystal spatial-light modulator.
ChemInform Abstract: cis‐2,3,4,4a,5,9b‐Hexahydroindeno(1,2‐b)‐1,4‐oxazine. (1990)

Abstract The title compounds (III) are obtained by a stereoselective one‐step Leuckart‐Wallach reaction of 2‐acetoxy‐1‐indanone (I) with the N‐alkylaminoethanols (II) in formic acid.
The effect of glycosylation on the structure of designed four-helix bundle motifs (2000)

A galactose-, 1, and a cellobiose derivative, 2, have been site selectively, post-translationally, incorporated into a folded helix-loop-helix dimer LA-42b in a one step reaction at room temperature. The structural effects on the folded peptide upon glycosylation have been studied by CD and NMR spectroscopy. The negative value of the mean residue ellipticity of the folded peptide, LA-42b, was raised from −19000 ± 1000 to −21200 ± 1000 deg cm2 dmol−1 upon introduction of the galactose derivative and to −19500 ± 1000 deg cm2 dmol−1 upon introduction of the cellobiose derivative, showing that the helical content was increased. The dissociation constant of the dimer decreased from 120 to 30 μM upon glycosylation.
A milk protein gene promoter directs the expression of human tissue plasminogen activator cDNA to the mammary gland in transgenic mice. (1988)

Whey acidic protein (WAP) is a major whey protein in mouse milk. Its gene is expressed in the lactating mammary gland and is inducible by steroid and peptide hormones. A series of transgenic mice containing a hybrid gene in which human tissue plasminogen activator (tPA) cDNA is under the control of the murine WAP gene promoter had previously been generated. In this study, 21 tissues from lactating and virgin transgenic female mice containing the WAP-tPA hybrid gene were screened for the distribution of murine WAP and human tPA transcripts. Like the endogenous WAP RNA, WAP-tPA RNA was expressed predominantly in mammary gland tissue and appeared to be inducible by lactation. Whereas WAP transcripts were not detected in 22 tissues of virgin mice, low levels of WAP-tPA RNA, which were not modulated during lactation, were found in tongue, kidney, and sublingual gland. These studies demonstrate that the WAP gene promoter can target the expression of a transgene to the mammary gland and that this expression is inducible during lactation.
LiInS2 and LiInSe2 : New Nonlinear Crystals for Continuous-Wave Difference-Frequency Generation in the Mid-Infrared (2006)

In this paper we report on the first demonstration, to the best of our knowledge, of continuous-wave (CW) difference-frequency generation (DFG) in LIS and LISe crystals in the mid-infrared between 5.5 and 11.3 mum. LiInSe <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> provides a transparency range slightly shifted to longer wavelengths (to about 12 mum, instead of ~11 mum for LiInS <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> ), and its nonlinear susceptibility is ~1.6 times higher than that of LiInS <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> . While LiInS <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> offers wider phase-matched spectral tuning. The high damage threshold combined with high thermal conductivity, broadband optical transparency and relatively high nonlinear optical coefficients makes LIS and LISe crystals attractive nonlinear optical materials for generation of powerful radiation in the deep mid-infrared by optical parametric interaction pumped with high laser power
Benefit of a monitoring system in situ for direction finding antennas (2013)

International audience
Underbalanced Data Acquisition: A Real-Time Paradigm (2003)

Abstract Formation damage and reservoir attributes can only be effectively evaluated with high quality, pertinent data. Underbalanced operations require a complex array of techniques that enable data to be effectively collated and managed. With the further advent of networking technologies the real-time transmission of this data is also now a viable option, leading to a myriad of benefits from accurate diagnosis and evaluation to real-time planning. This paper aims to describe data acquisition in underbalanced operations, commencing with a conventional acquisition setup, moving to a real-time operational case study. Underbalanced data acquisition has its roots in the traditional well testing setup, with the basic surface separator being standard. But due to the complexity of the operation many specializations and innovative modifications have been implemented, making it an entity in itself. The paper describes a typical underbalanced data acquisition setup. It then traverses to the latest high technology realm of real-time acquisition and transmission, which enables data to be acquired in the field and transmitted directly to the client's office. System setup, architecture (client – server) and limitations will be discussed and evaluated. The advantages of real-time data acquisition will be shown as well as current caveats and possible conceptual technological innovation to overcome these limitations. The future of underbalanced data acquisition is also taking a fundamental shift. Its amalgamation with the data analysis fields (i.e. non-simple processing) is leading to a fundamental shift in acquisition setups. These trends will be examined along with challenges and current industry direction. In the underbalanced sphere, the marriage between data collection and transmission within a real-time framework plays a vital role in optimizing results. In the past, data acquisition design and implementation has been relegated to the last phase of many operations. This paper aims to bring data acquisition, its current direction and setup to the forefront. Formation damage and ultimately recovery are important entities, but it is only with good quality data, available in a timely manner, that these can be representatively evaluated and the well understood.
Fundus Autofluorescence Imaging in Patients with Choroidal Melanoma (2022)

Choroidal melanocytic lesions require reliable and precise clinical examination and diagnosis to differentiate benign choroidal nevi from choroidal melanoma, as the latter may become life-threatening through metastatic disease. To come to an accurate diagnosis, as well as for monitoring, and to assess the efficacy of therapy, various imaging modalities may be used, one of which is non-invasive fundus autofluorescence (FAF) imaging using novel high-resolution digital imaging technology. FAF imaging is based on the visualization of intrinsic fluorophores in the ocular fundus. Lipofuscin and melanolipofuscin within the postmitotic retinal pigment epithelium (RPE) cells represent the major fluorophores that contribute to the FAF signal. In addition, the presence or loss of absorbing molecular constituents may have an impact on the FAF signal. A choroidal melanoma can cause secondary retinal and RPE alterations that affect the FAF signal (e.g., occurrence of orange pigment). Therefore, FAF imaging supports multimodal imaging and gives additional information over and above conventional imaging modalities regarding retinal metabolism and RPE health status. This article summarises the features of FAF imaging and the role of FAF imaging in the context of choroidal melanoma, both before and following therapeutic intervention.
Using Physical Theories to Infer Hidden Causal Structure (2004)

We argue that human judgments about hidden causal structure can be explained as the operation of domain-general statistical inference over causal models constructed using domain knowledge. We present Bayesian models of causal induction in two previous experiments and a new study. Hypothetical causal models are generated by theories expressing two essential aspects of abstract knowledge about causal mechanisms: which causal relations are plausible, and what functional form they take.
ChatGPT outscored human candidates in a virtual objective structured clinical examination in obstetrics and gynecology (2023)

ChatGPT generated factually accurate and contextually relevant structured discussion answers to complex and evolving clinical questions based on unfamiliar settings within a very short period. ChatGPT outperformed human candidates in several knowledge areas. Not all examiners were able to discern between human and ChatGPT responses. Our data highlight the emergent ability of natural language processing models to demonstrate fluid reasoning in unfamiliar environments and successfully compete with human candidates that have undergone extensive specialist training.
Frequency domain reflectometry NDE for aging cables in nuclear power plants (2017)

Degradation of the cable jacket, electrical insulation, and other cable components of installed cables within nuclear power plants (NPPs) is known to occur as a function of age, temperature, radiation, and other environmental factors. Although system tests verify cable function under normal loads, demonstration of some cable’s ability to perform under exceptional loads associated with design-basis events is essential to assuring plant integrity. The cable’s ability to perform safely over the initial 40-year planned and licensed life has generally been demonstrated and there have been very few age-related cable failures. With greater than 1000 km of power, control, instrumentation, and other cables typically found in an NPP, replacing all the cables would be a severe cost burden. Justification for life extension to 60 and 80 years requires a cable aging management program that includes condition monitoring to justify cable performance under normal operation as well as accident conditions. A variety of tests are available to assess various aspects of electrical and mechanical cable performance, but none are suitable for all cable configurations nor does any single test confirm all features of interest. One particularly promising test that is beginning to be used more and more by utilities is frequency domain reflectometry (FDR). FDR is a nondestructive electrical inspection technique used to detect and localize faults in power and communication system conductors along the length of a cable from a single connection point. FDR detects discontinuities in the electrical impedance that arise due to cable splices or similar changes along the path of the conductor pair. In addition, FDR has the potential to provide sensitivity to insulation degradation by detecting small changes in impedance between the cable conductors being examined. The technique is also sensitive to cable bends, the particular lay of the cable in tray, proximity to other cable, and other factors that bear consideration when interpreting the test results. This paper examines various influences on the FDR approach and compares results of three different instruments to assess accelerated aging damage among several NPP representative cables.
First approved inhaled insulin therapy for diabetes mellitus (2006)

The long-term benefits of tight glycemic control in preventing microvascular and macrovascular complications are well established in both Type 1 diabetes mellitus (Type 1 DM) and Type 2 diabetes mellitus (Type 2 DM). Nonetheless, achievement of recommended haemoglobin A1c (HbA(1c)) goals (< or = 6.5 - 7.0%) has remained elusive, especially in patients with diabetes who require insulin therapy. Delayed/suboptimal titration of insulin is partly related to poor acceptance of multiple injection regimen by both physicians and patients. EXUBERA (human insulin [rDNA origin]; Pfizer), the first approved inhaled insulin for the treatment of diabetic patients, has been shown to be safe and as effective as regular/rapidly acting insulin in improving glycemic control. In addition to controlling postprandial glucose excursions, EXUBERA exerts a major action to reduce fasting plasma glucose (FPG) concentration. Thus, it has the potential to be used as a monotherapy in Type 2 DM, as well as in combination with an insulin sensitizer in Type 2 DM or in combination with long-acting insulin in both Type 2 DM and Type 1 DM.
[Reconstruction of the long bones of the legs in children via free vascularized transplant of the fibula after resection for sarcoma]. (1996)

Nineteen children were operated on between 1985 and 1994. All the patients presented a sarcoma of long bones: osteosarcoma: 12 and Ewing's sarcoma: 7. They were operated on: resection and reconstruction of the long bones with a free vascularised fibula. Pre and post-operative chemotherapy was used. The average follow-up was 3 years (between 10 years and 1 year). The mean bone defect was 20 cm (between 32 and 11 cm). Boys were more frequently encountered [12]. Average age was 9.5 years. The pathological bone was: femur: 14, tibia: 4, humerus 1. The approach needs usually two incisions for femoral bone: the internal incision allows us to prepare the recipient vessels: deep femoral vessels in 11 cases. In 18 cases, union occurred in less than 14 months. One case of pseudarthrosis occurred. Immediate follow-up was simple in 17 cases. Infection was observed in 2 cases. Secondly, the most frequent complications were: fracture of the fibula: 6 cases, vicious cal: 2 cases; delayed union: 6 cases; stiffness: 2 cases. One patient died later from pulmonary metastasis. Solid osteosynthesis of the member and of the free vascularised fibula permit to shorten these delays. Success depends on two criteria: the graft thickening of the fibula and union of the fibula at both ends. The micro vascular anastomoses must be excellent. Twelve children had bone union with only one operation. In the 6 cases of delayed union, secondary bone grafts give consolidation. The comparison of this technique with standard treatment showed an evident superiority of the free vascularised fibula transplant in extensive defects of bone. The fibula is a life bone which permits rapid union with a short hospitalization, a quick recovery and an early return to school. Free vascularised fibula permit to ameliorate the quality of survival.
Monte Carlo study of the critical behavior of random bond Potts models (1999)

We present results of Monte Carlo simulations of random bond Potts models in two dimensions, for different numbers of Potts states q. We introduce a simple scheme which yields continuous self-dual distributions of the interactions. As expected, we find multifractal behavior of the correlation functions at the critical point and obtain estimates of the exponent ${\ensuremath{\eta}}_{n}$ for several moments n of the correlation functions, including typical $(\stackrel{\ensuremath{\rightarrow}}{n}0)$, average $(n=1)$, and others. In addition, for $q=8$, we find that there is only a single correlation length exponent $\ensuremath{\nu}$ describing the correlation length away from criticality. This is numerically very close to the pure Ising value $\ensuremath{\nu}=1$.
Dynamics of drug binding to the hERG channel: an in silico cardiac action potential model for early safety assessment (2011)

Pharmaceutical companies are under-pressure to produce potential safe drugs (i.e., no effect on cardiac action potential (AP) and QT interval). Early testing strategies to reduce this risk rely on concentration-effect (C-E) curve data obtained from a panel of heterologously-expressed key ion channels (ICs) using standard IonWorks™ voltage protocols. We had previously presented an in silico canine midmyocardial AP model that uses C-E data to predict changes in AP duration (APD; Hussein L et al., 2010 SPS meeting). We have now investigated whether incorporating the dynamics of drug binding to the hERG channel might improve the accuracy of the model. New IonWorks™ protocols were used to extract binding kinetics of dofetilide, almokalant and cisapride at ~20ºC. Data were fitted with a newly developed hERG model to obtain rate constants for drug binding and unbinding. Rate constants were then incorporated into a new canine IKr model developed at ~37ºC for simulating APs at various concentrations and pacing frequencies. As seen experimentally, AP simulations predict that all three drugs evoked concentration-dependent increase in APD. If instead a traditional C-E curve was employed, results show that APD increases could be significantly under-predicted for cisapride (31% vs. 44% at 1µM) and almokalant (36% vs. 54% at 3µM) at 1.5Hz. Thus, predictivity of the current AP model can be improved with new alternative IonWorks™ protocols. This has the potential to enhance upstream understanding of direct IC modulation of the AP via a rapid cost-effective in silico evaluation.
X-ray structure, reactivity and catalytic properties of a (cyclopentadienone)ruthenium dimer, [(C4Ph4CO)(CO)2Ru]2 (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTX-ray structure, reactivity and catalytic properties of a (cyclopentadienone)ruthenium dimer, [(C4Ph4CO)(CO)2Ru]2Martin J. Mays, Michael J. Morris, Paul R. Raithby, Youval Shvo, and Dorotha CzarkieCite this: Organometallics 1989, 8, 5, 1162–1167Publication Date (Print):May 1, 1989Publication History Published online1 May 2002Published inissue 1 May 1989https://pubs.acs.org/doi/10.1021/om00107a006https://doi.org/10.1021/om00107a006research-articleACS PublicationsRequest reuse permissionsArticle Views424Altmetric-Citations53LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Amygdala real‐time functional magnetic resonance imaging neurofeedback for major depressive disorder: A review (2018)

Advances in imaging technologies have allowed for the analysis of functional magnetic resonance imaging data in real-time (rtfMRI), leading to the development of neurofeedback (nf) training. This rtfMRI-nf training utilizes functional magnetic resonance imaging (fMRI) tomographic localization capacity to allow a person to see and regulate the localized hemodynamic signal from his or her own brain. In this review, we summarize the results of several studies that have developed and applied neurofeedback training to healthy and depressed individuals with the amygdala as the neurofeedback target and the goal to increase the hemodynamic response during positive autobiographical memory recall. We review these studies and highlight some of the challenges and advances in developing an rtfMRI-nf paradigm for broader use in psychiatric populations. The work described focuses on our line of research aiming to develop the rtfMRI-nf into an intervention, and includes a discussion of the selection of a region of interest for feedback, selecting a control condition, behavioral and cognitive effects of training, and predicting which participants are most likely to respond well to training. While the results of these studies are encouraging and suggest the clinical potential of amygdala rtfMRI-nf in alleviating symptoms of major depressive disorder, larger studies are warranted to confirm its efficacy.
On Performance Improvement of Gain-Scheduled Model Reference Adaptive Control Laws (2020)

Adaptive control laws are important tools for reducing system error between uncertain dynamical system trajectories and given desired reference model trajectories, but their transient performance can be unpredictable. Specifically, during transient periods, the system may significantly deviate from reference model behavior while the adaptive portion of the controller is still learning. This paper addresses transient performance of a model reference adaptive control scheme for uncertain dynamical systems with a gain-scheduled reference model. In the proposed control scheme, a gain-scheduled command governor is incorporated to reduce the system state error during transient periods to achieve desirable transient performance. With the addition of low-frequency learning incorporated into the parameter adjustment mechanism of the adaptive controller, faster learning rates can be implemented without the risk of inducing high-frequency oscillations in the closed-loop signals.
Laser Doppler Technique for Absolute Measurement of Blood Speed in Retinal Vessels (1987)

We describe an electrooptical laser Doppler system and technique of data analysis that provides absolute measurements of the speed of red blood cells flowing at discrete, selectable sites in the retinal vasculature. We present in vitro test measurements of the instrumentation as well as an example of an in vivo measurement from a patient with retinal vascular disease. We also present experimental data leading to the derivation of the relationship between the blood speeds measured in retinal arteries during the minimum diastolic and maximum systolic phases of the cardiac cycle and the time-averaged blood speed. Mean blood flow rate is calculated using the time-averaged speed and the cross-sectional area of the vessel at the measurement site. We discuss the criteria for selection of the measurement sites and assess the reproducibility of the measurements. We conclude that measurements on retinal arteries are less susceptible to experimental artifacts and provide more information than do measurements on retinal veins. The system is currently being used clinically in studies of retinal circulatory alterations in patients with diabetic retinopathy, arterial occlusive disease, retinal detachment, and carotid artery disease.