gebhart/patrepeval huggingface dataset:
FORMAS ORGANIZACIONAIS NO SETOR DE INTERMEDIAÇÃO FINANCEIRA (2011)

Considerado o primeiro passo numa análise demográfica organizacional, a caracterização da forma organizacional define os limites entre as várias populações e permite compreender a dinâmica competitiva intra e interpopulações. De acordo com a literatura de Ecologia Organizacional, ao observar os tipos de empresas selecionadas numa determinada população organizacional, é possível identificar os critérios de seleção em funcionamento no ambiente competitivo. Em algumas populações de empresas, a própria legislação define os contornos das formas organizacionais, como é o caso das populações de empresas de intermediação financeira, foco deste artigo. Todavia, a legislação não é explícita no que diz respeito às dimensões da forma organizacional. Identificaram-se quatro aspectos da legislação (denominação social; objeto social; capital e patrimônio mínimo; natureza da propriedade e sociedade) correspondentes às seguintes dimensões: identidade, objetivos, recursos, controle e autoridade.
Binding and Biological Effects of Tumor Necrosis Factor and Gamma Interferon in Human Pancreatic Carcinoma Cells (1990)

The cytotoxic/cytostatic effects of recombinant human tumor necrosis factor alpha (rhTNF) and gamma interferon (rhIFN-gamma) were studied in five human pancreatic tumor cell lines. During a 48-h incubation, MIA PaCa-2 cells were most sensitive to rhTNF (56% cytotoxicity, 500 U/ml), T3M4 cells were most sensitive to rhIFN-gamma (54% cytostasis, 250 U/ml), and ASPC-1 and COLO 357 cells were most sensitive to the combination of rhTNF and rhIFN-gamma (56 and 55% cytotoxicity, respectively, 250 U/ml of each cytokine). The PANC-1 cells were relatively insensitive to either the individual or the combined effects of these cytokines. All five cell lines exhibited specific, high-affinity receptors for 125I-labeled rhTNF (480-8,610 sites/cell) and rhIFN-gamma (2,050-6,280 sites/cell). The MIA PaCa-2 cells, which were the most sensitive to the inhibitory effects of rhTNF, also possessed the largest number of 125I rhTNF receptors; all other cell lines had a relatively low number of binding sites and low sensitivity. In contrast, no direct correlation could be made between the number of IFN-gamma binding sites and inhibitory sensitivity in any of the cell lines. Incubation of COLO 357 cells at 37 degrees C with either 125I rhTNF or 125I rhINF-gamma led to internalization of the respective 125I-labeled ligand. Our findings document the presence of cytokine receptors in human pancreatic carcinoma cells and suggest that postreceptor events rather than differences in receptor number or affinity more likely govern the responsiveness of pancreatic cancer cells to TNF and IFN-gamma.
Quantitative single-particle analysis with the Aerodyne aerosol mass spectrometer: development of a new classification algorithm and its application to field data (2013)

Abstract. Single-particle mass spectrometry has proven a valuable tool for gaining information on the mixing state of aerosol particles. With the Aerodyne aerosol mass spectrometer (AMS) equipped with a light-scattering probe, non-refractory components of submicron particles with diameters larger than about 300 nm can even be quantified on a single-particle basis. Here, we present a new method for the analysis of AMS single-particle mass spectra. The developed algorithm classifies the particles according to their components (e.g. sulphate, nitrate, different types of organics) and simultaneously provides quantitative information about the composition of the single particles. This classification algorithm was validated by applying it to data acquired in laboratory experiments with particles of known composition, and applied to field data acquired during the MEGAPOLI summer campaign (July 2009) in Paris. As shown, it is not only possible to directly measure the mixing state of atmospheric particles, but also to directly observe repartitioning of semi-volatile species between gas and particle phase during the course of the day.
User Centric Identity Management (2005)

Identity management is traditionally seen from the serviceproviders’ point of view, meaning that it is an activity undertaken by the service provider to manage servi ce user identities. Traditional identity management systems are designed to be cost effective and scalab le primarily for the service providers, but not necessarily for the users, which often results in poor us ability. Users are, for example, often required to memorise multiple passwords for accessing different ser vices. This represents a minor inconvenience if users only access a few online services. However, with therapid increase in the uptake of online services, the traditional approach to identity management is a having serious negative effects on the user experience. The industry has responded by proposing ne w identity management models to improve the user experience, but in our view these proposals give lit tle relief to users at the cost of relatively high increase in server system complexity. This paper takes a new look at identity management, and proposes solutions that are designed to be cost effective and scalabl e from the users’ perspective, while at the same time being compatible with traditional identity manag ement systems.
Nutzung von Constrained Beamformem zur Verbesserung der Bitfehlerrate von CDMA-basierten Mobilfunk-Systemen (1999)

The performance enhancements that can be achieved by employing constrained beamformers in code division multiple access cellular radio systems is investigated in this paper. It is shown in the paper which improvements on the bit error rate of the uplink channel (link from the mobile units to the base station) are possible using constrained beamformers. We use the Gaussian technique to find an accurate approximation to the probability of data bit error developed for direct-sequence spread-spectrum multiple-access packet radio systems. Analytical results and simulations are presented which demonstrate that constrained beamformers at the base station can improve the reverse channel performance. Upper and lower bounds for the improvements are given in the paper.
<title>Long-period gratings as flow sensors for liquid-composite molding</title> (2000)

One of the most important issues in liquid composite molding (LCM) is the complete saturation of the preform by the resin to eliminate voids or dry spots in the structure which could later adversely affect the structural integrity of the part. While there have been efforts in developing reliable mold filling simulations for LCM, very few successful flow sensing systems exist for detecting actual resin arrival during mold filling. In this study, the feasibility of using optical fibers with long period gratings (LPG) as sensors for monitoring flow in the LCM process was investigated. An advantage of using LPGs is that they are more robust and less susceptible to background noise than simple bare fibers. Furthermore, the location of resin arrival can be easily identified as the signals from each LPG uniquely correspond to predetermined wavelengths along the source spectrum. The LPGs are sensitive to changes in the refractive index and register a strong signal change when covered with resin. In this study, the LPG sensors were placed in the middle of a preform stack inside a mold and the sensor response after the mold was properly closed, and when the resin covered a particular LPG was monitored. An assortment of preforms, which included random mats and unidirectional fabrics, with a series of fiber volume fractions were used to determine their effects on the sensor response.
Effect of Electrolyte on the Performance of Anodic Titania Metal-Insulator-Metal Capacitors (2013)

In this paper, we report the fabrication of TiO2 metal insulator metal capacitor using various electrolytes in anodization process. The capacitors exhibit a high capacitance density of &gt;30 fF/mu m(2). We have discussed the effect of different electrolyte solutions on the electrical and structural properties of anodized TiO2 MIM Capacitors.
Gut epithelial and vascular barrier abnormalities in patients with chronic intestinal pseudo‐obstruction (2019)

The absence of oligomers demonstrated in our study suggests that IEBV is altered in CIPO. The mechanism leading to oligomerization is occludin-dependent in AN and INF, whereas is ZO-1-dependent in DEG. Our study provides support to IEVB abnormalities contributing to CIPO clinical and histopathological features.
ChemInform Abstract: A NOVEL TYPE REARRANGEMENT IN CYCLIC β‐DICARBONYL COMPOUNDS IN STRONG ACID MEDIA (1981)

Abstract Bei Bestrahlung in FSO 3 H oder 98proz. H 2 SO 4 isomerisieren ‐sich die Dione (Ia) und (Ib) zu den Dihydropyranonen (II).
Balancing selection at a premature stop mutation in the myostatin gene underlies a recessive leg weakness syndrome in pigs (2019)

Balancing selection provides a plausible explanation for the maintenance of deleterious alleles at moderate frequency in livestock, including lethal recessives exhibiting heterozygous advantage in carriers. In the current study, a leg weakness syndrome causing mortality of piglets in a commercial line showed monogenic recessive inheritance, and a region on chromosome 15 associated with the syndrome was identified by homozygosity mapping. Whole genome resequencing of cases and controls identified a mutation causing a premature stop codon within exon 3 of the porcine Myostatin (MSTN) gene, similar to those causing a double-muscling phenotype observed in several mammalian species. The MSTN mutation was in Hardy-Weinberg equilibrium in the population at birth, but significantly distorted amongst animals still in the herd at 110 kg, due to an absence of homozygous mutant genotypes. In heterozygous form, the MSTN mutation was associated with a major increase in muscle depth and decrease in fat depth, suggesting that the deleterious allele was maintained at moderate frequency due to heterozygous advantage (allele frequency, q = 0.22). Knockout of the porcine MSTN by gene editing has previously been linked to problems of low piglet survival and lameness. This MSTN mutation is an example of putative balancing selection in livestock, providing a plausible explanation for the lack of disrupting MSTN mutations in pigs despite many generations of selection for lean growth.
An Efficient High-Yield Synthesis of d-ribo-Phytosphingosine (2006)

[Structure: see text] [4R-[4alpha(S),5alpha]]-2,2-Dimethyl-4-(2-oxo-5-vinyl[1,3]dioxolan-4-yl)oxazolidine-3-carboxylic acid tert-butyl ester 5a, obtained in excellent yield and diastereoselectivity by the alpha-hydroxyallylation of the Garner aldehyde (4), is exploited in a novel high-yield synthesis of D-ribo-phytosphingosine (8), using microwave-enhanced cross metathesis as the key step in the chain elongation.
Abstract 4463: Targeting SN38 delivery to gastrointestinal cancer cells using a fucose-bound nanoparticle approach (2014)

Abstract Background &amp; Aims: Prognosis of patients with metastatic colorectal cancer (CRC) has been improving by introduction of molecular targeting therapy combined with chemotherapeutic agents. However, metastatic CRC still needs new strategies to improve treatment efficacy and survival rate. Increased expression of fucosyltransferases (FUTs) is common in CRC cells. FUTs are key enzymes accelerating malignant transformation through the fucosylation of different sialylated precursors, suggesting a crucial requirement for fucose by metastatic CRC cells. With this in mind, we developed fucose-bound nanoparticles as vehicles for delivery of anticancer drugs specifically to CRC cells. Methods: L-fucose-bound liposomes were produced by the modified cholate dialysis method as vehicles for delivery of Cy5.5, FAM and SN38. The production of CA19-9 was measured by enzyme-linked immunosorbent assay. The CRC cell lines were exposed to SN38 or L-fucose-bound liposomes carrying SN38, and cytotoxicity was monitored with BrdU assay. Introduction of Cy5.5 or FAM by L-fucose-bound liposomes was analyzed by flow cytometry or fluorescence microscopy. The effect of L-fucose-bound liposome carrying SN38 in vivo was analyzed by intravenous injection in mice engrafted with CRC cell lines. All statistical tests were two-sided. Results: L-fucose-bound liposomes containing Cy5.5 or SN38 were effectively delivered into CA19-9 expressing CRC cancer cells. Excess L-fucose decreased the efficiency of Cy5.5 introduction by L-fucose-bound liposomes, suggesting L-fucose-receptor dependency. Intravenously injected L-fucose-bound liposomes carrying SN38 were successfully delivered to CRC cells, mediating efficient tumor growth inhibition as well as prolonging survival in mouse xenograft models. Conclusions: Fucose-bound liposomes carrying anti-cancer drugs should provide a new strategy for patients with colorectal cancer. Citation Format: Junji Kato, Rishu Takimoto, Takahiro Osuga, Michihiro Ono, Masahiro Hirakawa, Makoto Yoshida, Yasushi Sato, Fumito Tamura. Targeting SN38 delivery to gastrointestinal cancer cells using a fucose-bound nanoparticle approach. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 4463. doi:10.1158/1538-7445.AM2014-4463
A 2.5 Gb/s flash all-optical analog-to-digital converter (2002)

We present the design and demonstration of an 8-bit flash all-optical A/D converter whose attractive features include 1) direct optical sampling of the input RF signal, 2) optical quantization, 3) flash architecture allowing for post electronic signal processing, and 4) low-power consumption.
REJECTION OF EMERGING ORGANIC MICROPOLLUTANTS IN NANOFILTRATION/REVERSE OSMOSIS MEMBRANE APPLICATIONS (2004)

REJECTION OF EMERGING ORGANIC MICROPOLLUTANTS IN NANOFILTRATION/REVERSE OSMOSIS MEMBRANE APPLICATIONSThis study aimed to investigate factors affecting the rejection of emerging trace organics by a variety of commercial reverse osmosis (RO), nanofiltration (NF), and ultra-low pressure RO membranes during laboratory-scale experiments. Findings of this study indicated that rejection of negatively charged organics was driven by a combination of steric and electrostatic exclusion, which was...Author(s)Jörg E. DrewesPei XuChristopher BellonaGary AmyTae-Uk KimMark AdamThomas HebererSourceProceedings of the Water Environment FederationSubjectSession 1: AEESP Lecture and Fate, Transport and Treatment of Emerging Micro-PollutantsDocument typeConference PaperPublisherWater Environment FederationPrint publication date Jan, 2004ISSN1938-6478SICI1938-6478(20040101)2004:16L.77;1-DOI10.2175/193864704784147548Volume / Issue2004 / 16Content sourceWEFTECFirst / last page(s)77 - 96Copyright2004Word count160
Pyrin- and CARD-only Proteins as Regulators of NLR Functions (2013)

Upon activation Nod-like receptors (NLRs) assemble into multi-protein complexes such as the NODosome and inflammasome. This process relies upon homo domain interactions between the structurally related Pyrin and caspase-recruitment (CARD) domains and adaptor proteins, such as ASC, or effector proteins, such as caspase-1. Although a variety of NLRP and NLRC complexes have been described along with their activating stimuli and associated proteins, less familiar are processes limiting assembly and/or promoting dissociation of NLR complexes. Given the importance of limiting harmful, chronic inflammation, such regulatory mechanisms are significant and likely numerous. Proteins comprised of a solitary Pyrin domain (Pyrin-only) or CARD domain (CARD-only) posses an obvious potential ability to act as competitive inhibitors of NLR complexes. Indeed, both Pyrin-only proteins (POPs) and CARD-only proteins (COPs) have been described as regulators of caspase-1 and/or NLR-inflammasome activation and not surprisingly as factors mediating pathogenesis. Although clear examples of pathogen encoded POPs are currently limited to members of the poxviridae, the human genome likely encodes three POPs (POP1, POP2, and a potential POP3), of which only POP2 is known to prevent NLR:ASC interaction, and three COPs (COP/Pseudo-ICE, INCA, and ICEBERG), initially described for their ability to inhibit caspase-1 activity. Surprisingly, among eukaryotic species POPs and COPs appear to be evolutionarily recent and restricted to higher primates, suggesting strong selective pressures driving their emergence. Despite the importance of understanding the regulation of NLR functions, relatively little attention has been devoted to revealing the biological impact of these intriguing proteins. This review highlights the current state of our understanding of POPs and COPs with attention to protein interaction, functions, evolution, implications for health and disease, and outstanding questions.
Meeting Report: From human genetic variations to prediction of risks and responses to drugs and the environment (2007)

Article Meeting Report: From human genetic variations to prediction of risks and responses to drugs and the environment was published on March 1, 2007 in the journal Clinical Chemistry and Laboratory Medicine (CCLM) (volume 45, issue 3).
The Nightmare Quality of Life Questionnaire (2021)

The NQoL has demonstrable construct validity and reliability and represents a promising multi-dimensional instrument to assess outcome measures for quality of life in patients with nightmares.
Concept and Features of Arrester Operating Duty Test in The Japanese Standard (2008)

The Japanese Electrotechnical Committee (JEC) of surge arresters has made great efforts to establish several new standards of metal-oxide surge arresters (MOSA), because the dramatic and continuous advance in the MOSA technology over the last 30 years required the new and improved test methods in succession. In the study to establish these standards, how to evaluate the MOSA performance against the energy duties has been usually the main topic because the energy duties are significantly related to the size of zinc-oxide elements and the construction of MOSA. This paper describes the concept and features of arrester operating duty tests in the JEC standards comparing with that in the standard of the International Electrotechnical Commission (IEC) and also mentions the points at issues to be studied in the future which is common to both the JEC and IEC standards. The continuous study on the improvement of the standards is required in cooperation with the activities of IEC and the Internaltional Council on Large Electric Systems (CIGRE: Conseil International des Grands Reseaux Electriques) taking into account of the latest world trend and the state-of-the-art technologies.
Development of Intraoperative Plantar Pressure Measurement System Considering Weight Bearing Axis and Center of Pressure (2022)

To prevent postoperative complications in corrective surgery for foot deformities such as hallux valgus and pes planus, it is critical to quantitatively predict the postoperative standing-position plantar pressure distribution during the operation. The authors have previously proposed an intraoperative plantar pressure measurement system (IPPM) that allows for the measurement of a supine patient’s plantar pressure distribution that is equivalent to that in the standing position. This system consists of an IPPM device comprising of a force plate and pressure distribution sensor, an optical three-dimensional position measurement device, a navigation monitor, and a PC. The plantar pressure distribution in the standing position is reproduced by navigating the operator, as he or she presses the IPPM device against the patient’s sole so that the weight-bearing axis (floor reaction force vector) and femoral head center are as close to each other as possible. However, in our previous study, the reproducibility of the standing position plantar pressure distribution was insufficient. Therefore, in the present study, we add a navigational function that can be used to bring the centers of pressure in the standing position and under measurement, as well as to correct the IPPM’s self-weight in the measured force. The improved device was used in an experiment with nine healthy subjects, and the similarity of the plantar pressure distribution in the standing and supine positions was evaluated using normalized cross-correlation, yielding an average of 0.90. Furthermore, in an evaluation experiment with ten orthopedic surgeons, it was observed that using the system reproduced the plantar pressure distribution significantly better than when the system was not used. These results indicate that the present system can predict the plantar pressure distribution in the standing position. We believe that this system can contribute to reducing complications after foot surgery.
Integration of forward-looking infrared (FLIR) and traffic information for moving obstacle detection with integrity (2009)

This paper discusses the integration of Forward-looking Infrared (FLIR) and traffic information from, for example, the Automatic Dependent Surveillance - Broadcast (ADS-B) or the Traffic Information Service-Broadcast (TIS-B). The goal of this integration method is to obtain an improved state estimate of a moving obstacle within the Field-of-View of the FLIR with added integrity. The focus of the paper will be on the approach phase of the flight. The paper will address methods to extract moving objects from the FLIR imagery and geo-reference these objects using outputs of both the onboard Global Positioning System (GPS) and the Inertial Navigation System (INS). The proposed extraction method uses a priori airport information and terrain databases. Furthermore, state information from the traffic information sources will be extracted and integrated with the state estimates from the FLIR. Finally, a method will be addressed that performs a consistency check between both sources of traffic information. The methods discussed in this paper will be evaluated using flight test data collected with a Gulfstream V in Reno, NV (GVSITE) and simulated ADS-B.