gebhart/patrepeval huggingface dataset:
Lithology and Fluid Prediction in Exploration: Think Vectors! (2003)

For decades, the seismic information that has been used to estimate lithological and fluid&lt;br&gt;properties of a propagating medium has been data in scalar form. For example, marine&lt;br&gt;seismic data have been generated with scalar sources (air guns suspended in water) and&lt;br&gt;recorded with scalar sensors (hydrophones).
Crystal Structure, Diffusion Path, and Oxygen Permeability of a Pr2NiO4-Based Mixed Conductor (Pr0.9La0.1)2(Ni0.74Cu0.21Ga0.05)O4+δ (2010)

We have investigated in situ the crystal structure, oxygen diffusion path, oxygen permeation rate, and electrical conductivity of a doped praseodymium nickel oxide, Pr(2)NiO(4)-based mixed conductor, (Pr(0.9)La(0.1))(2)(Ni(0.74)Cu(0.21)Ga(0.05))O(4+delta) (PLNCG) in air between 27 degrees C and 1015.6 degrees C. The PLNCG has a tetragonal I4/mmm K(2)NiF(4)-type structure which consists of a (Pr(0.9)La(0.1))(Ni(0.74)Cu(0.21)Ga(0.05))O(3) perovskite unit and a (Pr(0.9)La(0.1))O rock salt unit in the whole temperature range. Both experimental and theoretical electron density maps indicated two-dimensional networks of (Ni(0.74)Cu(0.21)Ga(0.05))-O covalent bonds in PLNCG. Highest occupied molecular orbitals (HOMO) in PLNCG demonstrate that the electron-hole conduction occurs via Ni and Cu atoms in the (Ni(0.74)Cu(0.21)Ga(0.05))-O layer. The bulk oxygen permeation rate was high (137 mumol cm(-2) min(-1) at 1000 degrees C), and its activation energy was low (51 kJ mol(-1) at 950 degrees C). The Rietveld method, maximum-entropy method (MEM), and MEM-based pattern fitting analyses of neutron and synchrotron diffraction data indicate a large anisotropic thermal motion of the apical O2 oxygen at the 4e site (0, 0, z; z approximately 0.2) in the (Pr(0.9)La(0.1))(Ni(0.74)Cu(0.21)Ga(0.05))O(3) perovskite unit. Neutron and synchrotron diffraction data and theoretical structural optimization show the interstitial oxygen (O3) atom at (x, 0, z) (x approximately 0.6 and z approximately 0.2). The nuclear density analysis indicates that the bulk oxide-ion diffusion, which is responsible for the high oxygen permeation rate, occurs through the interstitial O3 and anisotropic apical O2 sites. The nuclear density at the bottleneck on the oxygen diffusion path increases with temperature and with the oxygen permeation rate. The activation energy from the nuclear density at the bottleneck decreases with temperature, which is consistent with the decrease of the activation energy from oxygen permeation rate. The extremely low activation energy (12 kJ mol(-1) at 900 degrees C) from the nuclear density at the bottleneck indicates possible higher bulk oxygen permeation rates in quality single crystals and epitaxial thin films.
Short-Range Order in a Metal−Organic Network (2009)

Supramolecular assemblies on surfaces usually possess a long-range order controlled by the shape of the building blocks and the interactions between them. In this paper, we demonstrate that such a building block concept is applicable also for short-range ordered systems when used in combination with Monte Carlo (MC) techniques. Specifically, we focus on a structure that consists of a mixture of metal−organic complexes and organic trimers distributed on a hexagonal lattice. This distribution obeys a short-range order (SRO) governed by hydrogen bonds between the different types of lattice occupants. We show that this SRO, which is directly observed by scanning tunneling microscopy, can be predicted with high accuracy by MC simulations using pairwise interaction energy parameters which were determined by ab initio calculations.
Research on Hotel Customer Relationship Management System Based on the Classification Algorithm (2019)

The hotel management relationship is a good business strategy for hotels, which can promote the development of a hotel, when a classification algorithm is applied to customer relationship management system. First, the classification algorithm is based on a support vector machine is studied, the nearest neighbor sample density is used, and the corresponding mathematical model is constructed. Second, the procedure of a classification algorithm based on fuzzy support vector machine is designed. Third, a customer acquisition plan based on a classification algorithm is analyzed. Finally, a hotel is used as the research object, and a customer acquisition analysis is carried out, and the results show that the new method has quicker training speed and higher classification correctness.
[Airway involvement in the postoperative period of carotid endarterectomy. Report of a case]. (1993)

We report a case of a fifty-seven year old man that was diagnosed a bilateral carotid disease and a carotid endarterectomy was practiced on him in the left carotid, and afterwards in a 12 day lapsus of time, the same was done in the right carotid. In the course of the immediate post-operative period, the patient presented a neck haematoma which required its removal and afterwards he developed a glottis oedema which called for the realisation of a tracheotomy in order to control the airway.
Transcriptional regulation by thyroid hormone of an mRNA homologous to a protease inhibitor (1986)

We have previously cloned a cDNA of a rat liver mRNA, designated 4-12B, markedly induced by triiodothyronine (T3) at a pretranslational level [Magnuson, M.A., Dozin, B., & Nikodem, V.M. (1985) J. Biol. Chem. 260, 5906-5912]. Here we show that this hormonal effect is due in part to an increase of the rate of transcription of the 4-12B gene. In addition, the nucleotide sequence of 4-12B cDNA has been determined, revealing significant similarity with the sequences of the superfamily of serine protease inhibitors and a very high homology with contrapsin, a mouse serum trypsin inhibitor, at the level of nucleotide and amino acid sequence (77.9 and 66.8%, respectively). The optimized alignment of the putative reactive center region of 4-12B with four related members of this superfamily revealed that lysine-serine residues are located at the reactive site or adjacent to it, thus suggesting that the triiodothyronine-regulated rat 4-12B mRNA might code for a protease inhibitor with trypsin-like specificity. Although not enough data are presently available to assign definitively antitryptic activity to this protein, the high degree of similarity with members of the superfamily of serine protease inhibitors leaves no doubt that 4-12B is a member of this superfamily.
Some anticonvulsant drugs alter monoamine‐mediated behaviour in mice in ways similar to electroconvulsive shock; implications for antidepressant therapy (1985)

The effects in mice of administration of the anticonvulsants, progabide, sodium valproate, diazepam, carbamazepine and phenytoin on 5-hydroxytryptophan (5-HTP)-induced head-twitch, apomorphine-induced locomotion, clonidine-induced sedation, and beta-adrenoceptor and 5-HT2 receptor number have been examined. Repeated progabide administration (400 mg kg-1, i.p. twice daily for 14 days) enhanced the head-twitch response the effect lasting for over 8 days after the last dose, and also increased 5-HT2 receptor number in frontal cortex. Progabide (400 mg kg-1, i.p.) enhanced the head-twitch response when given once daily for 10 days and when given intermittently (5 times over 10 days) but not after 1 day of administration. Repeated Na valproate (400 mg kg-1, i.p.) also increased the 5-HTP-induced head-twitch response and 5-HT2 receptor number in the frontal cortex when given twice daily for 14 days, but no behavioural enhancement was seen after 10 days' treatment. Diazepam (1.25 mg kg-1, i.p.) twice daily for 14 days increased the head-twitch response and 5-HT2 receptor number. Repeated progabide and valproate (but not diazepam) administration attenuated the sedation response to the alpha 2-adrenoceptor agonist, clonidine (0.15 mg kg-1) but neither drug altered beta-adrenoceptor number in the cerebral cortex. No changes in apomorphine-induced locomotor behaviour were seen after progabide, valproate or diazepam. Repeated carbamazepine (20 mg kg-1) or phenytoin (40 mg kg-1) administration failed to alter any of the biochemical or behavioural parameters listed above. Like repeated electroconvulsive shock (ECS), progabide altered the head-twitch response, clonidine-induced sedation response and 5-HT2 receptor number. Unlike repeated ECS, it did not alter beta-adrenoceptor number or the apomorphine-induced locomotor response. These data suggest that ECS may produce some changes in monoamine function by altering GABA metabolism as has previously been postulated.
[Expression regulation of the protelomerase gene of the bacteriophage N15]. (2004)

The N15 bacteriophage, when in the lysogenic state, does not integrate into the chromosome; in fact, it exists as a linear plasmid with the covalently closed ends. Upon infection, the phage DNA circularizes via its cohesive ends, after which a specific enzyme, the N15 protelomerase, cuts the circular molecule thus generating a linear plasmid with the covalently closed telomeres. Protelomerase generates, as the replication of plasmid prophage proceeds, the hairpin telomeres in replicated molecules. We identified the promoter of the protelomerase gene and demonstrated that it could be repressed presumably due to its binding with 3 tosL sites overlapping the promoter. We also found the transformation efficiency of E. coli cells of linear DNA with hairpin telomeres to be approximately 100-fold lower versus the circular DNA of the same size. At the same time, presence of the N15 prophage or of the protelomerase-expressing vector enhances, in a strain being transformed, the efficiency of its transformation by linear DNA up to a level ensured in transformation by circular plasmids. We believe that protelomerase, while binding with the hairpin telomeres, protects the latter from degradation by cellular nucleases.
Water Plasma Generation Under Atmospheric Pressure for Waste Treatment (2005)

DC lOO%-steam plasma characteristics were investigated for the application of halogenated hydrocarbon decomposition because steam plasmas are chemically reactive. However, plasma system generally requires complex subsystems such as steam generators and cooling units. The presented steam plasma system is a portable light-weight plasma generation system that does not require any gas supply unit. The system has high-energy efficiency because it does not need additional cooling water. Electrodes of high durability are required for a DC lOO%-steam plasma because the electrodes are exposed to reactive conditions. Thus, the electrode's characteristics were also investigated under different configurations and conditions. Keywords: CFC decomposition, halon decomposition, steam plasma, thermal plasma, and waste treatment.
An Integrated Approach for Creating Model Diesel Fuels (2004)

This paper describes a methodology that has been developed to facilitate a detailed study of molecular composition effects on particulate matter emissions in advanced diesel engines. This includes a sophisticated numerical optimization algorithm to formulate well-characterized diesel fuel blends and an analytical method to characterize diesel fuels more accurately than previously possible. These tools are described, together with application to the formulation of test fuels with identical boiling point distribution and cetane number, but differing molecular composition. Test results are discussed from an advanced high-speed direct injection diesel engine for several of these fuels, demonstrating the improved insight and understanding available from these combined techniques.
Computational Prediction of MicroRNAs Encoded in Viral and Other Genomes (2006)

We present an overview of selected computational methods for microRNA prediction. It is especially aimed at viral miRNA detection. As the number of microRNAs increases and the range of genomes encoding miRNAs expands, it seems that these small regulators have a more important role than has been previously thought. Most microRNAs have been detected by cloning and Northern blotting, but experimental methods are biased towards abundant microRNAs as well as being time-consuming. Computational detection methods must therefore be refined to serve as a faster, better, and more affordable method for microRNA detection. We also present data from a small study investigating the problems of computational miRNA prediction. Our findings suggest that the prediction of microRNA precursor candidates is fairly easy, while excluding false positives as well as exact prediction of the mature microRNA is hard. Finally, we discuss possible improvements to computational microRNA detection.
Early Results from a Phase II Study of Lenalidomide Monotherapy in Relapsed/Refractory Indolent Non-Hodgkin’s Lymphoma. (2006)

Abstract Background: Lenalidomide (Revlimid®), an immunomodulatory drug (IMiD®), was recently approved in the US for treatment of relapsed/refractory multiple myeloma and myelodysplastic syndromes associated with a deletion 5q[31] cytogenetic abnormality. Lenalidomide also has demonstrated activity in chronic lymphocytic leukemia and cutaneous T-cell lymphoma while thalidomide, a less potent IMiD®, has activity in non-Hodgkin’s lymphoma (NHL) as both monotherapy and in combination with rituximab. Aim: To assess the safety and efficacy of lenalidomide monotherapy in subjects with relapsed/refractory indolent NHL. Methods: Subjects with relapsed/refractory indolent NHL following at least 1 prior treatment regimen with measurable disease are eligible. Subjects receive 25 mg lenalidomide orally once daily on Days 1–21 every 28 days and continue therapy for 52 weeks as tolerated or until disease progression. Response and progression are evaluated using the IWLRC methodology. Results: As of July 25, 2006, 23 subjects of a planned 40 have enrolled and received drug. Fifteen subjects are currently evaluable for tumor response. The median age of the 15 response-evaluable subjects is 64 (54–82) and 5 are female. Histology is small lymphocytic lymphoma [SLL] (n=8), follicular center lymphoma grades 1,2 [FL] (n=5) and nodal marginal B-cell lymphoma [NML] (n=2). Median time from diagnosis to lenalidomide monotherapy is 7.6 (3–14) years and median number of prior treatment regimens per subject is 3 (1–17). Two subjects (13%) exhibited an objective partial response (PR) at four months. Both responses, one FL and one NML, occurred in subjects with substantial tumor burden of 61.8 cm2 and 80.3 cm2, respectively. The 4-month time-to-response for these indolent NHL subjects is longer than the 2-month median time-to-response in aggressive NHL subjects (n=7) following lenalidomide monotherapy. Seven patients had stable disease (SD) for a tumor control rate (TCR) of 60% and 6 had progressive disease (PD). Grade 3 or 4 adverse events occurred in 9 (39%) subjects. These were predominantly Grade 3 hematological events (neutropenia, thrombocytopenia) with only 3 subjects (13%) experiencing a Grade 4 adverse reaction (all neutropenia). Conclusion: Early results of lenalidomide monotherapy in indolent NHL show evidence of activity with a safety profile similar to that established previously in other hematological malignancies.
Regulation of Product Formation in Bacteroides xylanolyticus X5-1 by Interspecies Electron Transfer (1994)

Bacteroides xylanolyticus X5-1 was grown in pure culture and in mixed culture with Methanospirillum hungatei JF-1 under xylose limitation in the chemostat. In the pure culture, ethanol, acetate, CO(2), and hydrogen were the products. In the mixed culture, acetate, CO(2), and presumably hydrogen were the only products formed by B. xylanolyticus X5-1. The biomass yield of B. xylanolyticus X5-1 increased because of cocultivation. In cell extracts of the pure culture, both NAD- and NADP-dependent acetaldehyde dehydrogenase and ethanol dehydrogenase activities were found. In cell extracts of the mixed culture, activities of these enzymes were not detected. Inhibition of methanogenesis in the mixed culture by the addition of bromoethanosulfonic acid (BES) resulted in an accumulation of H(2), ethanol, and formate. Immediately after the addition of BES, NAD-dependent acetaldehyde dehydrogenase and ethanol dehydrogenase activities were detected. After a short lag phase, a NADP-dependent ethanol dehydrogenase was also detectable. The induction of acetaldehyde dehydrogenase and ethanol dehydrogenase was inhibited by chloramphenicol, suggesting de novo synthesis of these enzymes. These results are consistent with a model in which the shift in product formation caused by interspecies electron transfer is regulated at the level of enzyme synthesis.
MP09-18 BIOPSY-DETECTED GLEASON PATTERN 5 IS A PARTICULARLY STRONG PREOPERATIVE PREDICTOR OF RECURRENCE, METASTASIS, AND MORTALITY IN MEN WITH HIGH-RISK PROSTATE CANCER (2016)

lesion regression in response to either systemic or targeted therapy (51%).
NMR Structural and Kinetic Assignment of Fluoro-3H-naphthopyran Photomerocyanines¶ (2001)

The kinetic and structural behavior of a photochromic compound, 3-(2-fluorophenyl)-3-phenyl-3H-naphtho[2,1-b]pyran (F-Py), was investigated using 1H and 19F nuclear magnetic resonance (NMR) spectroscopy. Upon irradiation, the four theoretically predicted photomerocyanines appear along with a fifth form X, whose final structure has not been elucidated. This last form and two of the photomerocyanines are thermally labile, whereas the other two do not show any signs of decay. The system has been analyzed by NMR spectroscopy. This led to the structural assignment of each photomerocyanine. The kinetics of the thermal bleaching were monitored by directly and separately measuring the concentrations of each species at regular time intervals using 19F NMR spectroscopy. We therefore propose a plausible reaction mechanism. On the basis of this mechanism, the mathematical treatment and the study of the effects of temperature led to the determination of the kinetic and thermodynamic parameters (rate coefficients, enthalpy and entropy of activation) of this photochromic system. The leading role of the labile intermediate X on the formation of trans-transoid-cis (TTC) and cis-transoid-cis (CTC) photomerocyanines is pointed out.
Hailey-Hailey Disease Successfully Treated with Carbon Dioxide Laser-A Case Report (2007)

A 45-year-old man presented with erythematous vesicles and erosions on erythematous backgrounds on his axillae, groin, and popliteal fossae. He had been treated with corticosteroid ointments for several years, but the clinical course waxed and waned, and the lesions never completely disappeared. A skin biopsy specimen from his left axilla revealed suprabasal acantholysis (a ”dilapidated brick wall”). Diagnosis of recurrent Hailey-Hailey disease was made after careful analysis of the clinical and histopathological features. We administered a CO2 laser to eradicate the unresponsive remnants of the lesion. The operative site re-epithelialized within 3 weeks. One year after the treatment, there was no evidence of recurrence. For recalcitrant cases of Hailey-Hailey disease, as in this case, the use of a CO2 laser may be an effective therapeutic modality.
ON THE PLATELET COUNT AND BLEEDING TIME IN DISEASES OF THE BLOOD (1920)

The blood platelets, the third corpuscular element of the blood, have since the fundamental work of Bizzozero, been the object of many researches, the results of which, in brief, are the following: The platelets are a normal element of the blood of great importance for coagulation and thrombosis. The place of origin of these bodies is not known with absolute certainty, although most authors believe in Wright's theory, that traces their descent to the megakaryocytes of the bone marrow. The platelet count normally varies more than does the number of red and white cells. The platelet count is low in genuine, idiopathic purpura, and in certain diseases of the blood and infections (pernicious anemia and typhoid). When the number of platelets falls below certain values, the symptoms of a hemorrhagic diathesis occur. The methods for counting the platelets hitherto published, all use blood from a skin prick and may be divided in two groups
Genetic Analysis of Default Mating Behavior in Saccharomyces cerevisiae (1997)

Haploid Saccharomyces cerevisiae cells find each other during conjugation by orienting their growth toward each other along pheromone gradients (chemotropism). However, when their receptors are saturated for pheromone binding, yeast cells must select a mate by executing a default pathway in which they choose a mating partner at random. We previously demonstrated that this default pathway requires the SPA2 gene. In this report we show that the default mating pathway also requires the AXL1, FUS1, FUS2, FUS3, PEA2, RVS161, and BNI1 genes. These genes, including SPA2, are also important for efficient cell fusion during chemotropic mating. Cells containing null mutations in these genes display defects in cell fusion that subtly affect mating efficiency. In addition, we found that the defect in default mating caused by mutations in SPA2 is partially suppressed by multiple copies of two genes, FUS2 and MFA2. These findings uncover a molecular relationship between default mating and cell fusion. Moreover, because axl1 mutants secrete reduced levels of a-factor and are defective at both cell fusion and default mating, these results reveal an important role for a-factor in cell fusion and default mating. We suggest that default mating places a more stringent requirement on some aspects of cell fusion than does chemotropic mating.
Modelling and analysis of the ARINC specification 629 CP MAC layer protocol (2002)

The main concepts and the architecture of the 629 CP ARINC protocol are presented. The emphasis is put on the transmitter scheduler with its two main parts: the timers and the transmitter control. The protocol (which includes a lot of time constraints) is modelled with stochastic timed Petri nets. Its real time and fault tolerance properties are demonstrated.
Sound Localization-Based Navigational User Interfaces (2006)

In this paper, we propose and compare three navigational user interfaces that are based on acoustic information. The user can navigate through a Web page or change slides in a presentation by changing its spatial location. To this end, we employ an array of 24 microphones to record speech signals and localize the speaker. The proposed interfaces are: 1) The parallax system, which behaves as if the user is looking out of a window, 2) The corner system, which resizes each image based on the proximity of the speaker to the corners of the environment, and 3) The tiled system, which divides the environment into a number of tiles and loads the image corresponding to the tile on which the user is standing on. A set of experiments were performed on 15 participants, which showed that the interaction time required for the tiled system and the corner system is far less than that required for the parallax system. The participants were also asked to rank the ease of use of each of the interfaces; it was observed that the users are more comfortable with an interface that requires minimal interaction time
Circulating high-molecular-weight adiponectin is upregulated in preeclampsia and is related to insulin sensitivity and renal function (2008)

We show that maternal HMW adiponectin and total adiponectin serum concentrations are significantly increased in PE and are positively associated with markers of insulin sensitivity and renal dysfunction. Adiponectin might be part of a physiological feedback mechanism improving insulin sensitivity and cardiovascular health in PE.