gebhart/patrepeval huggingface dataset:
Organocatalytic asymmetric Michael addition of α-aryl cyclopentanones to nitroolefins for construction of adjacent quaternary and tertiary stereocenters (2010)

The first asymmetric Michael addition of alpha-aryl cyclopentanones to nitroolefins for construction of adjacent quaternary and tertiary stereocenters has been achieved with excellent diastereo-/enantioselectivity.
Growth Regulator-Like Activity of Atrazine and Ametryne (1972)

Atrazine [2-chloro-4-(ethylamino)-6-(isopropylamino)- s -triazine] and 2-(ethylamino)-4-(isopropylamino)-6-(methylthio)- s -triazine (ametryne) were tested for growth regulatorlike effects. In the presence of 10 μg/ml of kinetin, atrazine had no effect on the growth of callus tissue of soybean (Glycine max Merr. ‘Lee’), but ametryne at 10 −14 M concentration stimulated callus growth and the production of roots. High concentrations of both atrazine and ametryne inhibited the growth of excised roots of tomato (Lycopersicon esculentum Miller ‘Atkinson’). Ametryne, and to a lesser extent atrazine, increased percent germination of seed of lettuce (Lactuca sativa L. ‘Grand Rapids’) and tobacco (Nicotiana tobaccum L. ‘Sansum’) exposed to only 4 min of red light. Both atrazine and ametryne stimulated adventitious root formation by excised hypocotyls of mung beans (Phaseolus aureus Roxb.) in the absence of 10 ppm of exogenous indoleacetic acid (IAA) but not in its presence. A high concentration of atrazine (10 −6 M) in the presence of IAA decreased root initiation in comparison with the IAA-treated controls.
Re: Prognostic Model for Survival in Patients With Metastatic Renal Cell Carcinoma: Results From the International Kidney Cancer Working Group (2012)

No AccessJournal of UrologyAdult Urology1 Mar 2012Re: Prognostic Model for Survival in Patients With Metastatic Renal Cell Carcinoma: Results From the International Kidney Cancer Working Group Samir S. TanejaM.D. Samir S. TanejaSamir S. Taneja More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2011.11.064AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Re: Prognostic Model for Survival in Patients With Metastatic Renal Cell Carcinoma: Results From the International Kidney Cancer Working Group." The Journal of Urology, 187(3), pp. 874–875 © 2012 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 187Issue 3March 2012Page: 874-875 Advertisement Copyright & Permissions© 2012 by American Urological Association Education and Research, Inc.MetricsAuthor Information Samir S. Taneja More articles by this author Expand All Advertisement PDF downloadLoading ...
Photoinduced Dynamics of Bis-dipyrrinato-palladium(II) and Porphodimethenato-palladium(II) Complexes: Governing Near Infrared Phosphorescence by Structural Restriction (2018)

Although superficially similar, the bis-dipyrrinato-palladium(II) complex 1 and the bridged porphodimethenato-palladium(II) complex 2 possess dramatically different structures in the ground state (proved by X-ray structure analysis) and in the singlet and triplet excited states (calculated by density functional theory methods). While complex 2 is rather rigid, complex 1 undergoes a major structural reorganization in the excited state to yield a disphenoidal (seesaw) triplet state. The dynamics of the excited states were probed by transient absorption spectroscopy with femtosecond and nanosecond time resolution and with fluorescence upconversion and yield intersystem crossing rate constants of ca. (13-16 ps)<sup>-1</sup>. The observation of significant near infrared phosphorescence in complex 2 but the absence of any emission in complex 1 in fluid solution could be rationalized by the structural reorganization of 1 which results in a nonemissive triplet metal centered state.
Distributed beamforming for information transfer in sensor networks (2004)

Energy efficient transfer of data from sensors is a fundamental problem in sensor networks. In this paper, we propose a distributed beamforming approach to this problem, with a cluster of sensors emulating a centralized antenna array. While it is well-known that beamforming can provide large performance gains, such gains presuppose not only accurate knowledge of the channel, but also time and phase synchronization at the transmitter. We propose explicit methods for achieving such synchronization in a distributed fashion, and analyze the effects of various sources of coordination error on the attained performance. We find that, as long as the error in range measurements or placement of the sensor nodes is within a fraction of a carrier wavelength, the proposed distributed beamforming strategies achieve most of the gains available from a centralized beamformer.
NUFFT- & GPU-Based Fast Imaging of Vegetation (2011)

We develop an effective algorithm, based on the filtered backprojection (FBP) approach, for the imaging of vegetation. Under the FBP scheme, the reconstruction amounts at a non-trivial Fourier inversion, since the data are Fourier samples arranged on a non-Cartesian grid. The computational issue is efficiently tackled by Non-Uniform Fast Fourier Transforms (NUFFTs), whose complexity grows asymptotically as that of a standard FFT. Furthermore, significant speed-ups, as compared to fast CPU implementations, are obtained by a parallel versions of the NUFFT algorithm, purposely designed to be run on Graphic Processing Units (GPUs) by using the CUDA language. The performance of the parallel algorithm has been assessed in comparison to a CPU-multicore accelerated, Matlab implementation of the same routine, to other CPU-multicore accelerated implementations based on standard FFT and employing linear, cubic, spline and sinc interpolations and to a different, parallel algorithm exploiting a parallel linear interpolation stage. The proposed approach has resulted the most computationally convenient. Furthermore, an indoor, polarimetric experimental setup is developed, capable to isolate and introduce, one at a time, different non-idealities of a real acquisition, as the sources (wind, rain) of temporal decorrelation. Experimental far-field polarimetric measurements on a thuja plicata (western redcedar) tree point out the performance of the set up algorithm, its robustness against data truncation and temporal decorrelation as well as the possibility of discriminating scatterers with different features within the investigated scene.
Magneto-Responsive Actuating Surfaces with Controlled Wettability and Optical Transmittance (2022)

The wettability of surfaces can be manipulated using actuating micro/nanostructures, as in the manipulation of water droplets with magnetic forces. Controlling water droplets with magneto-responsive surfaces is limited to optical applications, however, because these surfaces are normally opaque. Herein, we introduce a magneto-responsive actuating surface that is capable of controlling not only the wettability but also the optical transmittance. The magneto-responsive actuating surface is fabricated using a composite of iron particles with polydimethylsiloxane (PDMS). Thanks to the elastic properties of PDMS, fabricated microstructures' bending is induced by applying magnetic force. Therefore, the static/dynamic water contact angle and the optical transmittance can be controlled. Furthermore, as a feasible application, a sliding angle control system that depends on the magnet location is implemented. On the basis of the interesting characteristics of not only wettability but also optical transmittance, this study is expected to be widely used in various fields such as optics, surface self-cleaning systems of solar cells, and smart windows.
Linkage map ofCucumis meloincluding phenotypic traits and sequence-characterized genes (2003)

A new linkage map of Cucumis melo, derived from the F2 progeny of a cross between PI 414723 and C. melo 'TopMark' is presented. The map spans a total of 1421 cM and includes 179 points consisting of random amplified polymorphic DNA (RAPD), amplified fragment length polymorphism (AFLP), inter-simple sequence repeats (ISSRs), simple sequence repeats (SSRs), and restriction fragment length polymorphism (RFLP) markers. The map also includes an aphid resistance trait (Vat) and the sex type gene, andromonoecious (a), the two of which are important in resistance breeding and the control of hybrid seed production, as well as a seed-color gene, Wt-2. Most RFLPs represent sequence-characterized cDNA probes from C. melo and Cucumis sativus. These include resistance gene homologues and genes involved in various aspects of plant development and metabolism. A sub-set of our SSR and RFLP markers were also mapped, as part of this study, on additional mapping populations that were published for this species. This provides important reference points ("anchors"), enabling us to identify several linkage groups with respect to other melon maps.
Pharmacokinetics of a Slower Clearing Tissue Plasminogen Activator Variant, TNK-tPA, in Patients with Acute Myocardial Infarction (1998)

The rapid clearance of t-PA from plasma requires administration by intravenous (I.V.) infusion. A slower clearing, fibrin-specific rt-PA variant may allow single intravenous bolus administration, thereby simplifying dosing. This study was designed to characterize the pharmacokinetics of the slower clearing, fibrin-specific tissue-plasminogen activator variant, TNK-tPA, in patients with acute myocardial infarction (AMI) following a single I.V. bolus injection. Single I.V. bolus doses of 5 to 50 mg of TNK-tPA were studied in an open-label, multicenter, dose escalation study. A total of 113 AMI patients were enrolled. Blood sampling for pharmacokinetics was conducted in eighty-two patients (72 men, 10 women), with 5 to 27 patients per dose. TNK-tPA was administered as an I.V. bolus over 5-10 s. Following I.V. bolus administration, there was a biphasic elimination of TNK-tPA from plasma. The initial phase had a mean half-life that ranged from 11 +/- 5 to 20 +/- 6 min and was followed by a terminal phase with a mean half-life that ranged from 41 +/- 16 to 138 +/- 84 min. Mean TNK-tPA plasma clearance was 125 +/- 25 - 216 +/- 98 ml/min, and the initial volume of distribution was 4.3 +/- 2 - 8.4 +/- 6 1. A decrease in TNK-tPA plasma clearance with increasing TNK-tPA dose was noted. In addition, women and patients with lower body weight or older age had a slower plasma clearance. In conclusion, TNK-tPA has a slower plasma clearance in patients with AMI than that reported for rt-PA, allowing administration as a single I.V. bolus.
Construct Rigidity: Keystone for Treating Pelvic Discontinuity (2017)

Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
Phase Variation in H Type I and Lewis a Epitopes of Helicobacter pylori Lipopolysaccharide (2000)

Helicobacter pylori NCTC 11637 lipopolysaccharide (LPS) expresses the human blood group antigens Lewis x (Le(x)), Le(y), and H type I. In this report, we demonstrate that the H type I epitope displays high-frequency phase variation. One variant expressed Le(x) and Le(y) and no H type I as determined by serology; this switch was reversible. Insertional mutagenesis in NCTC 11637 of JHP563 (a poly(C) tract containing an open reading frame homologous to glycosyltransferases) yielded a transformant with a serotype similar to the phase variant. Structural analysis of the NCTC 11637 LPS confirmed the loss of the H type I epitope. Sequencing of JHP563 in strains NCTC 11637, an H type I-negative variant, and an H type I-positive switchback variant showed a C14 (gene on), C13 (gene off), and C14 tract, respectively. Inactivation of strain G27, which expresses Le(x), Le(y), H type I, and Le(a), yielded a transformant that expressed Le(x) and Le(y). We conclude that JHP563 encodes a beta3-galactosyltransferase involved in the biosynthesis of H type I and Le(a) and that phase variation in H type I is due to C-tract changes in this gene. A second H type I-negative variant (variant 3a) expressed Le(x) and Le(a) and had lost both H type I and Le(y) expression. Inactivation of HP093-HP094 resulted in a transformant expressing Le(x) and lacking Le(y) and H type I. Structural analysis of a mutant LPS confirmed the serological data. We conclude that the HP093-HP094 alpha2-fucosyltransferase (alpha2-FucT) gene product is involved in the biosynthesis of both Le(y) and Le(x). Finally, we inactivated HP0379 in strain 3a. The transformant had lost both Le(x) and Le(a) expression, which demonstrates that the HP0379 gene product is both an alpha3- and an alpha4-FucT. Our data provide understanding at the molecular level of how H. pylori is able to diversify in the host, a requirement likely essential for successful colonization and transmission.
LRP: Link quality‐aware queue‐based spectral clustering routing protocol for underwater acoustic sensor networks (2016)

Summary Recently, underwater acoustic sensor networks (UASNs) have been considered as a promising approach for monitoring and exploring the oceans in lieu of traditional underwater wireline instruments. As a result, a broad range of applications exists ranging from oil industry to aquaculture and includes oceanographic data collection, disaster prevention, offshore exploration, assisted navigation, tactical surveillance, and pollution monitoring. However, the unique characteristics of underwater acoustic communication channels, such as high bit error rate, limited bandwidth, and variable delay, lead to a large number of packet drops, low throughput, and significant waste of energy because of packets retransmission in these applications. Hence, designing an efficient and reliable data communication protocol between sensor nodes and the sink is crucial for successful data transmission in underwater applications. Accordingly, this paper is intended to introduce a novel nature‐inspired evolutionary link quality‐aware queue‐based spectral clustering routing protocol for UASN‐based underwater applications. Because of its distributed nature, link quality‐aware queue‐based spectral clustering routing protocol successfully distributes network data traffic load evenly in harsh underwater environments and avoids hotspot problems that occur near the sink. In addition, because of its double check mechanism for signal to noise ratio and Euclidean distance, it adopts opportunistically and provides reliable dynamic cluster‐based routing architecture in the entire network. To sum up, the proposed approach successfully finds the best forwarding relay node for data transmission and avoids path loops and packet losses in both sparse and densely deployed UASNs. Our experimental results obtained in a set of extensive simulation studies verify that the proposed protocol performs better than the existing routing protocols in terms of data delivery ratio, overall network throughput, end‐to‐end delay, and energy efficiency.
Comparison of performance of switching technologies on E Cigre motor simulation circuit (1989)

The Cigre motor simulation circuit is used to perform comparative switching tests with modern technologies, i.e. SF/sub 6/ and vacuum. The tests are aimed at comparing the overvoltage performance of medium-voltage circuit breakers in an accepted, standard circuit. The results are assessed in terms of the likely effects on main and interturn machine insulation. All types of switching devices tested generated acceptable levels of overvoltages due to simple current chopping in the circuit used. That is, the overvoltages generated were below the level at which motor insulation should be at risk. The phenomenon of multiple restriking was relatively frequently observed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Insulin-Like Growth Factor (IGF) Binding Protein-5 Blocks Skeletal Muscle Differentiation by Inhibiting IGF Actions (2007)

Signaling through the IGF-I receptor by locally produced IGF-I or -II is critical for normal skeletal muscle development and repair after injury. In most tissues, IGF action is modulated by IGF binding proteins (IGFBPs). IGFBP-5 is produced by muscle cells, and previous studies have suggested that when overexpressed it may either facilitate or inhibit IGF actions, and thus potentially enhance or diminish IGF-mediated myoblast differentiation or survival. To resolve these contradictory observations and discern the mechanisms of action of IGFBP-5, we studied its effects in cultured muscle cells. Purified wild-type (WT) mouse IGFBP-5 or a variant with diminished extracellular matrix binding (C domain mutant) each prevented differentiation at final concentrations as low as 3.5 nm, whereas analogs with reduced IGF binding (N domain mutant) were ineffective even at 100 nm. None of the IGFBP-5 variants altered cell number. An IGF-I analog (R(3)IGF-I) with diminished affinity for IGFBPs promoted full muscle differentiation in the presence of IGFBP-5(WT), showing that IGFBP-5 interferes with IGF-dependent signaling pathways in myoblasts. When IGFBP-5(WT) or variants were overexpressed by adenovirus-mediated gene transfer, concentrations in muscle culture medium reached 500 nm, and differentiation was inhibited, even by IGFBP-5(N). As 200 nm of purified IGFBP-5(N) prevented activation of the IGF-I receptor by 10 nm IGF-II as effectively as 2 nm of IGFBP-5(WT), our results not only demonstrate that IGFBP-5 variants with reduced IGF binding affinity impair muscle differentiation by blocking IGF actions, but underscore the need for caution when labeling effects of IGFBPs as IGF independent because even low-affinity analogs may potently inhibit IGF-I or -II if present at high enough concentrations in biological fluids.
SProxy: A Caching Infrastructure to Support Internet Streaming (2007)

Many algorithmic efforts have been made to address technical issues in designing a streaming media caching proxy. Typical of those are segment-based caching approaches that efficiently cache large media objects in segments which reduces the startup latency while ensuring continuous streaming. However, few systems have been practically implemented and deployed. The implementation and deployment efforts are hindered by several factors: 1) streaming of media content in complicated data formats is difficult; 2) typical streaming protocols such as RTP often run on UDP; in practice, UDP traffic is likely to be blocked by firewalls at the client side due to security considerations; and 3) coordination between caching discrete object segments and streaming continuous media data is challenging. To address these problems, we have designed and implemented a segment-based streaming media proxy, called SProxy. This proxy system has the following merits. First, SProxy leverages existing Internet infrastructure to address the flash crowd. The content server is now free of the streaming duty while hosting streaming content through a regular Web server. Thus, UDP based streaming traffic from SProxy suffers less dropping and no blocking. Second, SProxy streams and caches media objects in small segments determined by the object popularity, causing very low startup latency, and significantly reducing network traffic. Finally, prefetching techniques are used to pro-actively preload uncached segments that are likely to be used soon, thus providing continuous streaming. SProxy has been extensively tested and we show that it provides high quality streaming delivery in both local area networks and wide area networks (e.g., between Japan and the U.S.).
Characterization of Barley Leaf Tolerance to Drought Stress by Chlorophyll Fluorescence and Electron Paramagnetic Resonance Studies (2014)

Abstract Two kinds of barley genotypes with various water‐stress tolerances, tolerant Cam/B1 and sensitive Maresi, were subjected to 10‐day soil‐drought stress in seedling and flag leaf developmental phases. After this time, both genotypes regardless of the growth stage showed a decrease in quantum yield of PSII photochemistry (Φ PSII ) upon stress treatment; however, this effect was stronger in the sensitive plants than in the tolerant ones. The drought stress in the flag leaf stage was associated with an increase in superoxide dismutase ( SOD ) level in both genotypes, whereas in seedlings, this effect was observed only for Maresi. The activity of other enzymes (catalase and peroxidase) was changed only in small degree. An increase in proline levels and activities of Δ 1 ‐pyrroline‐5‐carboxylate synthetase (P5 CS ) and ornithine delta‐aminotransferase ( OAT ) were observed independently of genotype and the phase of plant development, whereas the activity pyruvate dehydrogenase ( PDH ) decreased in tolerant genotype. Moreover, changes in the concentration of monocarbohydrates (glucose and fructose) and dicarbohydrates (saccharose, raffinose and maltose) were found: in seedlings, the amount of all soluble sugars increased, while in flag leaves decreased. The drought treatment resulted in a drop in starch level in the tolerant genotype, but in the sensitive one, the content of this substance increased in both developmental stages. EPR studies allowed the determination of the amount and character of organic radicals present in leaves. In control conditions, the content of these radical species was higher in the sensitive genotype than in tolerant one and decreased upon water stress, with the exception of flag leaves of the sensitive plant. Simulation procedure revealed four types of signals in the EPR spectra. One of them was attributed to a chlorophyll a cation and decreased upon drought. The second, ascribed to semiquinone radicals, reflected the redox balance disturbed by water deficit. The two remaining signals were connected with carbon‐centred radicals situated in the carbohydrate matrix. Their number was correlated with starch concentration.