gebhart/patrepeval huggingface dataset:
Automated Phase Mapping with AgileFD and its Application to Light Absorber Discovery in the V–Mn–Nb Oxide System (2016)

Rapid construction of phase diagrams is a central tenet of combinatorial materials science with accelerated materials discovery efforts often hampered by challenges in interpreting combinatorial X-ray diffraction data sets, which we address by developing AgileFD, an artificial intelligence algorithm that enables rapid phase mapping from a combinatorial library of X-ray diffraction patterns. AgileFD models alloying-based peak shifting through a novel expansion of convolutional nonnegative matrix factorization, which not only improves the identification of constituent phases but also maps their concentration and lattice parameter as a function of composition. By incorporating Gibbs' phase rule into the algorithm, physically meaningful phase maps are obtained with unsupervised operation, and more refined solutions are attained by injecting expert knowledge of the system. The algorithm is demonstrated through investigation of the V-Mn-Nb oxide system where decomposition of eight oxide phases, including two with substantial alloying, provides the first phase map for this pseudoternary system. This phase map enables interpretation of high-throughput band gap data, leading to the discovery of new solar light absorbers and the alloying-based tuning of the direct-allowed band gap energy of MnV<sub>2</sub>O<sub>6</sub>. The open-source family of AgileFD algorithms can be implemented into a broad range of high throughput workflows to accelerate materials discovery.
Mutual coherence of laser solitons in coupled semiconductor resonators (2010)

International audience
Paper-Based Strips for the Electrochemical Detection of Single and Double Stranded DNA (2018)

The detection of double stranded DNA (dsDNA) is often associated with the use of laboratory-bound approaches and/or with the prior generation of single stranded DNA (ssDNA), making these methods not suitable for in situ monitoring, i.e., point-of-care diagnostics. Screen-printed technology, coupled to the use of triplex forming oligonucleotides (TFO) as the recognizing probes, offers a great possibility toward the development of portable analytical tools. Moreover, the continuous demand for sustainable processes and waste lowering have highlighted the role of paper-based substrates for manufacturing easy-to-use, low-cost, and sustainable electrochemical devices. In this work, filter paper and copy paper have been utilized to produce E-DNA strips. Gold nanoparticles (AuNPs) have been exploited to immobilize the methylene blue (MB)-tagged TFO and to enhance the charge transfer kinetics at the electrode surface. Both paper-based substrates have been electrochemically characterized, and in addition, the effect of the amount of waxed layers has been evaluated. The paper-based E-DNA strips have been challenged toward the detection of three model targets, obtaining 3 and 7 nM as the detection limit, respectively, for single and double stranded sequences. The repeatability of the manufacturing (homemade) process has been evaluated with a relative standard deviation of approximately 10%. The effectiveness of the filter paper-based platform has been also evaluated in undiluted serum obtaining a similar value of the detection limit (compared to the measurements carried out in buffer solution). In addition, a synthetic PCR amplified dsDNA sequence, related to HIV, has been detected in serum samples.
The 2016 revision of the WHO classification of tumours of the central nervous system (2017)

Abstract The revised fourth edition of the WHO classification of Tumours of the Central Nervous System, published in 2016, comprises several newly recognized tumour entities, and a significant restructuring of the classification, mainly based on genetic profiling. Glioblastomas are now classified into two major types. Isocitrate dehydrogenase (IDH)-wildtype glioblastoma (primary glioblastoma IDH-wildtype) develops rapidly de novo without a recognizable precursor lesion. IDH-mutant glioblastoma (secondary glioblastoma IDH-mutant) develops more slowly through malignant progression from diffuse or anaplastic astrocytoma. Medulloblastomas are now defined by combining histological patterns (classic, desmoplastic/nodular, extensive nodularity, anaplastic) and genetic hallmarks (WNT-activated; SHH-activated, TP53-mutant; SHH-activated, TP53-wildtype; non-WNT/non-SHH). Other newly recognized tumour entities include diffuse midline glioma, H3 K27M-mutant; ependymoma, RELA fusion-positive; and embryonal tumour with multilayered rosettes. The new classification is a significant step forward and will facilitate the development of novel targeted therapies of brain tumours.
Studies on key technologies of improving the kinematic accuracy of series mechanical arm (2017)

With the rapid development of economy and technology, China’s industrial production domain has achieved substantial progress. Widely application of industrial robot has directly manifested this progress. Series mechanical arm can be one of core technologies of industrial robot. As the application environment of industrial robot is getting more complicated, the kinematic accuracy of series mechanical arm is attracting more attention in this domain. Thus this article has carried out specific research on key technologies of improving the kinematic accuracy of industrial robot in hope of bringing inspirations for relevant researchers.
Beta Carotene Supplementation and Age-Related Maculopathy in a Randomized Trial of US Physicians (2007)

These randomized data relative to 12 years of treatment among a large population of apparently healthy men indicate that beta carotene supplementation has no beneficial or harmful effect on the incidence of ARM. Long-term supplemental use of beta carotene neither decreases nor increases the risk of ARM.
The lung microbiome in patients with pneumocystosis (2017)

The lower respiratory tract microbiome in patients with pneumocystosis does not appear to be determined by a specific microbial composition or to be dominated by a single bacterial species.
Crisis in Infectious Diseases: Time for a New Paradigm? (2008)

Current practices in the treatment of infectious diseases are the result of two fundamental changes in antimicrobial therapy that occurred in the mid-20th century : the transition from pathogen-specific therapy to non-pathogen-specific therapy and the shift toward emphasis on antiinfective strategies that target microbial pathogens over those that enhance host immunity. The alarming rise in antimicrobial-resistant strains, the increasing frequency of serious infections in immunocompromised patients, and the paucity of new types of antibiotics suggest the need for reevaluation of the manner in which infections are treated. In the short term, the situation may be addressed-at least in part-by increased emphasis on improved diagnosis and, when possible, the use of specific or narrow-spectrum treatments. In the long term, a return to pathogen-specific therapy, possibly in combination with adjunctive immunotherapy, may be an attractive and desirable option provided that significant advances are made in diagnostic microbiology and drug discovery.
Cooperative N-Heterocyclic Carbene/Lewis Acid Catalysis for Highly Stereoselective Annulation Reactions with Homoenolates (2010)

A new approach that takes advantage of N-heterocyclic carbene/Lewis acid cooperative catalysis provides access to cis-1,3,4-trisubstituted cyclopentenes from enals and chalcone derivatives with high levels of diastereoselectivity and enantioselectivity. The presence of Ti(OiPr)(4) as the Lewis acid allows for efficient substrate preorganization, which translates into high levels of diastereoselectivity. Additionally, we demonstrate the possibility of controlling the absolute stereochemistry of NHC-catalyzed reactions by employing a catalytic amount of a chiral Lewis acid as the unique source of optically active promoter.
Peak-to-Average Power Ratio (PAPR) Reduction Techniques of OFDM Signals (2008)

It is well-known that one of the most serious problems of Orthogonal Frequency Divison Multiplexing (OFDM) is its high Peak-to-Average Power Ratio (PAPR) which seriously limits the power efficiency of High Power Amplifier (HPA). This paper introduces various methodologies to cope with this problem.
Compressible flow at high pressure with linear equation of state (2018)

Compressible flow varies from ideal-gas behaviour at high pressures where molecular interactions become important. It is widely accepted that density is well described through a cubic equation of state while enthalpy and sound speed are functions of both temperature and pressure, based on two parameters, $A$ and $B$ , related to intermolecular attraction and repulsion, respectively. Assuming small variations from ideal-gas behaviour, a closed-form approximate solution is obtained that is valid over a wide range of conditions. An expansion in these molecular interaction parameters simplifies relations for flow variables, elucidating the role of molecular repulsion and attraction in variations from ideal-gas behaviour. Real-gas modifications in density, enthalpy and sound speed for a given pressure and temperature lead to variations in many basic compressible-flow configurations. Sometimes, the variations can be substantial in quantitative or qualitative terms. The new approach is applied to choked-nozzle flow, isentropic flow, nonlinear wave propagation and flow across a shock wave, all for a real gas. Modifications are obtained for allowable mass flow through a choked nozzle, nozzle thrust, sonic wave speed, Riemann invariants, Prandtl’s shock relation and the Rankine–Hugoniot relations. Forced acoustic oscillations can show substantial augmentation of pressure amplitudes when real-gas effects are taken into account. Shocks at higher temperatures and pressures can have larger pressure jumps with real-gas effects. Weak shocks decay to zero strength at sonic speed. The proposed framework can rely on any cubic equation of state and can be applied to multicomponent flows or to more complex flow configurations.
4 mA tDCS improves walking ability in PSP: A case study (P9-11.012) (2023)

<h3>Objective:</h3> The objective is to examine if tDCS can improve gait speed in people living with Progressive Supranuclear Palsy (PSP). <h3>Background:</h3> There is no current treatment for PSP. Neuromodulation with transcranial direct current stimulation (tDCS) works through modulating spontaneous activity of neural regions receiving electrical stimulation. The success of tDCS in individuals with motor-related diseases (Parkinson’s Disease and Stroke) indicates that it might be beneficial to individuals with PSP. Our lab (Chertkow-Roncero) has modeled electrical flow, finding that with two anode electrodes placed over the left and right deltoid muscles, and two cathode electrodes placed just ahead of the motor cortex on both sides (C3 &amp; C4), electrical stimulation occurs in midbrain and subthalamic regions. Using this PSP montage, a study from our lab has looked at the effects of tDCS on motor function in PSP, finding improvement persisting for a month. <h3>Design/Methods:</h3> An 84 year old lady with moderately severe PSP for 5 years and dependent on a walker, underwent two rounds of stimulation using the PSP montage, two months apart. Each round consisted of twelve tDCS sessions over three weeks. In the first week of both rounds, sham tDCS was given to establish a pre-stimulation baseline, while one of two real tDCS montages was given in weeks two and three of each round. tDCS was given at an intensity of 4 mA. Primary outcome measure was gait time which is the time required to walk four lengths of the gait mat(24 meters). <h3>Results:</h3> Significant improvement in gait time compared to baseline (26.84% improvement immediately after second round and 18.82% at 2 weeks post-stimulation) was noted after the second round. In both the rounds, she demonstrated improvement in cadence, stride length and stride velocity. <h3>Conclusions:</h3> These results suggest tDCS can provide a significant improvement in the walking ability of people living with PSP. <b>Disclosure:</b> Dr. Lahiri has nothing to disclose. Dr. Roncero has nothing to disclose. Miss Zhang has nothing to disclose. The institution of Dr. Chertkow has received research support from Hoffmann-La Roche Limited. The institution of Dr. Chertkow has received research support from Anavex Life Sciences. The institution of Dr. Chertkow has received research support from Alector Co.. The institution of Dr. Chertkow has received research support from Lilly.
Chameleon: A Hybrid Secure Computation Framework for Machine Learning Applications (2018)

We present Chameleon, a novel hybrid (mixed-protocol) framework for secure function evaluation (SFE) which enables two parties to jointly compute a function without disclosing their private inputs. Chameleon combines the best aspects of generic SFE protocols with the ones that are based upon additive secret sharing. In particular, the framework performs linear operations in the ring $\mathbb{Z}_{2^l}$ using additively secret shared values and nonlinear operations using Yao's Garbled Circuits or the Goldreich-Micali-Wigderson protocol. Chameleon departs from the common assumption of additive or linear secret sharing models where three or more parties need to communicate in the online phase: the framework allows two parties with private inputs to communicate in the online phase under the assumption of a third node generating correlated randomness in an offline phase. Almost all of the heavy cryptographic operations are precomputed in an offline phase which substantially reduces the communication overhead. Chameleon is both scalable and significantly more efficient than the ABY framework (NDSS'15) it is based on. Our framework supports signed fixed-point numbers. In particular, Chameleon's vector dot product of signed fixed-point numbers improves the efficiency of mining and classification of encrypted data for algorithms based upon heavy matrix multiplications. Our evaluation of Chameleon on a 5 layer convolutional deep neural network shows 133x and 4.2x faster executions than Microsoft CryptoNets (ICML'16) and MiniONN (CCS'17), respectively.
Guide modes in photonic crystal heterostructures composed of rotating non-circular air cylinders in two-dimensional lattices (2003)

We investigate the properties of guide modes localized at the interfaces of photonic crystal (PC) heterostructures which are composed of two semi-infinite two-dimensional PCs consisting of non-circular air cylinders with different rotating angles embedded in a homogeneous host dielectric. Photonic band gap structures are calculated with the use of the plane-wave expansion method in combination with a supercell technique. We consider various configurations, for instance, rectangular (square) lattice–rectangular (square) air cylinders, and different rotating angles of the cylinders in the lattices on either side of the interface of a heterostructure. We find that the absolute gap width and the number of guide modes strongly depend on geometric and physical parameters of the heterostructures. It is anticipated that the guide modes in such heterostructures can be engineered by adjusting parameters.
Squamous metaplasia of normal and carcinoma in situ of HPV 16-immortalized human endocervical cells. (1992)

The importance of cervical squamous metaplasia and human papillomavirus 16 (HPV 16) infection for cervical carcinoma has been well established. Nearly 87% of the intraepithelial neoplasia of the cervix occur in the transformation zone, which is composed of squamous metaplastic cells with unclear origin. HPV DNA, mostly HPV 16, has been found in 90% of cervical carcinomas, but only limited experimental data are available to discern the role of HPV 16 in this tissue specific oncogenesis. We have initiated in vivo studies of cultured endocervical cells as an experimental model system for development of cervical neoplasia. Using a modified in vivo implantation system, cultured normal endocervical epithelial cells formed epithelium resembling squamous metaplasia, whereas those immortalized by HPV 16 developed into lesions resembling carcinoma in situ. In contrast, their ectocervical counterparts formed well differentiated stratified squamous epithelium and a lesion with mild dysplastic change, respectively. The HPV 16-immortalized cells showed in vivo cytokeratin expression patterns similar to their respective normal counterparts, confirming their different origins. Thus, this study provides direct experimental evidence for the transformation of simple epithelial cells of endocervical origin into stratified squamous metaplasia and indicates the differential susceptibility of endo- and ectocervical epithelial cells for conversion to cancer by HPV 16.
Examination of the optimization of thin film transistor passivation with hydrogen electron cyclotron resonance plasmas (1992)

Hydrogen plasmas generated by electron cyclotron resonance currently provide the most efficient plasma exposure technique available for passivating the grain boundaries of polycrystalline silicon. In this report, we show that careful optimization may be required when using this passivation approach on polycrystalline silicon gated, polycrystalline silicon thin film transistors fabricated using low temperature oxides. Optimization is found to be necessary for thin film transistors (TFTs) with polycrystalline Si gates in order to prevent the onset of high leakage currents which can develop when exposures are too long. The effects of exposure time, substrate temperature, microwave power level, pressure, and plasma dilution with an inert gas are examined to determine the conditions for optimal improvement in electrical performance. A model is also presented to explain this need for optimization of the electron cyclotron resonance hydrogen plasma passivation of poly-Si TFTs.
THE EFFECT OF INCREASED RENAL VENOUS PRESSURE ON RENAL FUNCTION (1999)

s Of Papers To Be Presented At The Twenty-Ninth Annual Scientific Meeting Of The Western Trauma Association, February 28-March 6, 1999, Crested Butte, Colorado
Communication Technique for a Couselling Manager (2014)

Today, managers are turning to counselling as a method to deal with problem of employees as they feel responsible for the welfare of their workforce. Counselling is seen as a way of enhancing mental as well as emotional health of the employees in the organization. The health of the employees could be disrupted or disturbed due to various professional or personal reasons. The managers not only adopt counselling techniques but try to understand some of the major principles underlying human communication and more so, interpersonal communication. Since, interpersonal communication has been primarily based on human psychology; managers must be equipped with advanced communication skills apart from various levels of empathy.
Expression of c-Myc, c-Fos, and c-Jun in hepatocellular carcinoma (2001)

Because c-myc is a known inducer of wild type p53, decreased c-myc expression may lead to uncontrolled cell growth because of the lack of p53 expression that normally induces apoptosis. The coordinated expression of c-fos and c-jun in HCC may reflect the coordinated tumor cell cycle of progression and proliferation; however, future studies are required to elucidate this possibility.
Nano-Sized Fe(III) Oxide Particles Starting from an Innovative and Eco-Friendly Synthesis Method (2020)

This paper introduces an original, eco-friendly and scalable method to synthesize ferrihydrite nanoparticles in aqueous suspensions, which can also be used as a precursor to produce α-hematite nanoparticles. The method, never used before to synthesize iron oxides, is based on an ion exchange process allowing to operate in one-step, with reduced times, at room temperature and ambient pressure, and using cheap or renewable reagents. The influence of reagent concentrations and time of the process on the ferrihydrite features is considered. The transformation to hematite is then analyzed and discussed in relation to different procedures: (1) A natural aging in the water at room temperature; and (2) heat treatments at different temperatures and times. Structural and morphological features of the obtained nanoparticles are investigated by means of several techniques, such as X-ray diffraction, X-ray photoelectron spectroscopy, attenuated total reflectance Fourier transform infrared spectroscopy, transmission and scanning electron microscopy, thermal analysis, nitrogen adsorption and magnetic measurements. Ferrihydrite shows the typical spherical morphology and a very high specific surface area of 420 m<sup>2</sup>/g. Rhombohedral or plate-like hexagonal hematite nanoparticles are obtained by the two procedures, characterized by dimensions of 50 nm and 30 nm, respectively, and a specific surface area up to 57 m<sup>2</sup>/g, which is among the highest values reported in the literature for hematite NPs.
Supplementary Tables 1-2, Figures 1-2 from Distinctive MicroRNA Profiles Relating to Patient Survival in Esophageal Squamous Cell Carcinoma (2023)

Supplementary Tables 1-2, Figures 1-2 from Distinctive MicroRNA Profiles Relating to Patient Survival in Esophageal Squamous Cell Carcinoma
Method for Electric Parametric Characterization and Optimization of Electroporation on a Chip (2013)

We have developed a rapid method to optimize the electric parameters of cell electroporation. In our design, a pair of ring-dot formatted electrodes was used to generate a radial distribution of electric field from the center to the periphery. Varied electric field intensity was acquired in different annulus when an electric pulse was applied. Cells were cultured on the microchips for adherent cell electroporation and in situ observation. The electroporation parameters of electric field intensity were explored and evaluated in terms of cell viability and transfection efficiency. The optimization was performed in consideration of both cell viability, which was investigated to decrease as electric field increases, and the transfection rate, which normally increases at stronger electric field. The electroporation characteristics HEK-293A and Hela cells were investigated, and the optimum parameters were obtained. Verified by a commercial electroporation system as well as self-made microchips endowed the optimization with wider meaning. At last, as applications, we acquired the optimal electroporation pulse intensity of Neuro-2A cells and a type of primary cell (human umbilical vein endothelial cell, HUVEC) by one time electroporation using the proposed method.
Additive global cerebral blood flow normalization in arterial spin labeling perfusion imaging (2014)

To determine how different methods of normalizing for global cerebral blood flow (gCBF) affect image quality and sensitivity to cortical activation, pulsed arterial spin labeling (pASL) scans obtained during a visual task were normalized by either additive or multiplicative normalization of modal gCBF. Normalization by either method increased the statistical significance of cortical activation by a visual stimulus. However, image quality was superior with additive normalization by visual inspection, by comparing intensity histograms, and by reduction of the variability within gray and white matter.