gebhart/patrepeval huggingface dataset:
Data‐driven exploratory approach on player valuation in football transfer market (2019)

Summary Transfer markets in football have attracted the interest of researchers in economy and management. In this paper, we propose a high level analysis approach for classifying player valuation based on their performance during recent seasons. In particular, several data analysis techniques such as regression analysis, feature selection, and cluster analysis are presented for classifying players in term of performances and transfer fee. Specifically, by collecting and analyzing data from Wholescored , the largest detailed football statistics website, we have defined players into four groups, which include (1) Low performance and low transfer fee (LPLF), (2) Low performance and high transfer fee (LPHF), (3) high performance and high transfer fee (HPHF), and (4) high performance and low transfer fee (HPLF). The results in the implementation section show that, with the differences positions, there are different required skills that affect to the performance of players. We expect that this study can contribute to the management of Football Teams in terms of integrating these analyses into their management strategy.
Generation of high-power picosecond pulses from a gain-switched two-section quantum-well laser with a laterally tapered energy-storing section (1996)

We investigated experimentally the potential of generating high power gain-switched pulses from a two-section laser diode containing a laterally tapered energy-storing section and a ridge-waveguide modulation section. In particular, picosecond pulses with energies above 20 pJ and peak powers about 1 W were obtained by electrical pulse modulation at a repetition rate of 250 MHz. Large-signal operation up to the GHz range was also demonstrated. The lateral far-field pattern exhibited a single lobe subtending an angle near the diffraction limit, which showed that the lateral mode was well-controlled by the ridge-waveguide section.
Photosynthesis as a guide to small scale production of energy from CO2 (2018)

Photosynthesis as a guide to taking up CO2 and nutrient rich water in sunlight and give off O2 and water vapor is the topic of this research. Using photosynthesis as a guide, it has been researched on ways to take up CO2 and water and obtain fresh water, O2 and energy at a small scale.
The orally bioavailable met inhibitor PF-2341066 inhibits osteosarcoma growth and osteolysis/matrix production in a xenograft model (2011)

Osteosarcoma (OS) is the most common primary bone tumor in children and adolescents. Ninety percent of patients who present with metastatic and 30% to 40% of patients with nonmetastatic disease experience relapse, creating an urgent need for novel therapeutic strategies. The Met receptor tyrosine kinase and its ligand, hepatocyte growth factor (HGF), are important for mitosis, motility, and cell survival. Upregulation of Met/HGF signaling via receptor overexpression, amplification, or mutation drives the proliferation, invasiveness, and metastasis of a variety of cancer cells, including OS, prompting the development of Met/HGF inhibitors. OS cells depend on Met overexpression because introduction of dominant-negative Met inhibits in vivo tumorigenicity. Despite the importance of Met/HGF signaling in the development and maintenance of OS, the potential efficacy of pharmacologic Met inhibition in OS has been addressed only in in vitro studies. PF-2341066 is an orally bioavailable, selective ATP-competitive Met inhibitor that showed promising results recently in a phase I clinical trial in non-small cell lung cancer (NSCLC) patients. We tested the ability of PF-2341066 to inhibit malignant properties of osteosarcoma cells in vitro and orthotopic xenograft growth in vivo. In vitro, PF-2341066 inhibited osteosarcoma behavior associated with primary tumor growth (eg, proliferation and survival) as well as metastasis (eg, invasion and clonogenicity). In nude mice treated with PF-2341066 via oral gavage, the growth and associated osteolysis and extracortical bone matrix formation of osteosarcoma xenografts were inhibited by PF-2341066. PF-2341066 may represent an effective new systemic therapy for localized and potentially disseminated osteosarcoma.
Intake of Soy Protein Isolate Alters Hepatic Gene Expression in Rats (2005)

Soy protein isolate (SPI) can elicit various physiological effects such as cholesterol lowering and antiobesity effects. To examine whether hepatic gene expression is altered by SPI intake, rats were fed an SPI or casein diet for 8 weeks. After 8 weeks of feeding, liver weight and plasma triglyceride and cholesterol levels were significantly lower in the SPI group than in the casein group. Hepatic gene expression was investigated using DNA microarrays. The expression profiles and statistical analysis showed clear and significant differences between the SPI and casein groups (p < 0.05); in the SPI group, 63 genes were up-regulated and 57 genes were down-regulated, most involved in various physiological functions such as lipid metabolism, antioxidant activity, transcriptional regulation, and energy metabolism. Especially in lipid metabolism, the down-regulated genes are related to fatty acid synthesis and the up-regulated genes are related to cholesterol synthesis and steroid catabolism. These results suggest that SPI intake could maintain homeostasis primarily by modulating lipid and energy metabolism.
The Surgical Treatment of Fibrous Dysplasia (1985)

Fibrous dysplasia is a congenital, metabolic, nonfamilial disturbance that occurs in one or more bones, at times in association with skin pigmentations or endocrine abnormalities. The authors report on a large personal series of 23 patients with fibrous dysplasia involving the craniofacial skeleton. The etiology, clinical findings, pathology, and differential diagnosis of this condition are reviewed and a working hypothesis is offered for the pathophysiology of this disorder. Approximately one-third of patients with fibrous dysplasia have involvement of the cranial or facial bones. The authors describe how new techniques in craniofacial surgery have opened up additional options for this group of patients. Deformity, diplopia, proptosis, sinus infection, deafness, and loss of vision, are some of the clinical features that may require early surgical management. Evidence is given to support more complete resection of bony lesions with immediate reconstruction by several techniques. The removal, remodeling, and replacement of the dysplastic bone is advanced as a promising new method for the management of these complex problems. Successful use of this technique in four patients is reported. In a separate group of patients, continuing good experience is reported with cranio-orbital reconstruction by means of large methyl-methacrylate implants. Both of these surgical approaches eliminate donor site morbidity that results from the grafting of large amounts of autogenous bone. Both techniques also avoid the problems associated with postoperative absorption of bone grafting. Several patients are reported in whom serious disturbances in visual function appear to have been prevented or reversed by early treatment. Factors leading to malignant change in patients with fibrous dysplasia are reviewed.
Participation of redundant transfer ribonucleic acids from yeast in protein synthesis (1968)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTParticipation of redundant transfer ribonucleic acids from yeast in protein synthesisP. L. Bergquist, D. J. W. Burns, and Carol A. PlinstonCite this: Biochemistry 1968, 7, 5, 1751–1761Publication Date (Print):May 1, 1968Publication History Published online1 May 2002Published inissue 1 May 1968https://pubs.acs.org/doi/10.1021/bi00845a020https://doi.org/10.1021/bi00845a020research-articleACS PublicationsRequest reuse permissionsArticle Views19Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Age‐related cannibalism and horizontal transmission of a nuclear polyhedrosis virus in larval Spodoptera frugiperda (1999)

Summary 1. Experiments were carried out to investigate the incidence of cannibalism throughout the larval development of the noctuid moth Spodoptera frugiperda , and to examine the risk of infection from consuming conspecifics infected with a nuclear polyhedrosis virus (SfNPV). 2. Cannibalism was observed commonly even when food was not limiting, but occurred more frequently at low food quantities and/or high rearing densities. The sex of the larvae had no effect on the incidence of cannibalistic behaviour, however the probability of cannibalism occurring was affected by larval stage. The frequency of cannibalism was significantly higher among fifth‐ and sixth‐instar larvae than among earlier instars, and larvae were more likely to consume younger conspecifics than larvae of the same stage. 3. Fifth‐instar larvae offered fourth‐instar victims fed equally on healthy larvae, virus‐infected larvae (2 days post‐infection), uninfected corpses, and virus‐killed corpses (6 days post‐infection). Horizontal transmission of SfNPV was only recorded in larvae offered virus‐killed corpses, however, and total mortality in this treatment was only 32%. 4. In a similar experiment, fourth‐instar larvae avoided cannibalising virus‐killed corpses. Horizontal transmission of SfNPV was recorded in fourth‐instar larvae that consumed 2‐day post‐infected larvae. The low incidence of cannibalism observed in fourth‐instar larvae, however, suggests that this is unlikely to provide an important route for the transmission of SfNPV.
Ring‐opening metathesis copolymerization employing ruthenium‐based metathesis catalysts (1995)

Abstract The copolymerization of both high‐ and low‐strain cyclic olefins employing three ruthenium‐based metathesis catalysts is desribed. The effect of the ligand environment as well as the nature of the carbene on the copolymerizations is discussed.
Substratum-bound elastin peptide inhibits aortic smooth muscle cell migration in vitro. (1987)

Migration of smooth muscle cells (SMCs) of the media through the internal elastic lamina to the intima in response to various chemoattractants is considered to be an important event in the development of atherosclerosis. We evaluated the influence of elastin peptides prepared from normal aorta on migration of cultured rat aortic SMCs in vitro. Studies with filters coated with elastin peptides in a modified Boyden's chamber showed that the migratory response of cultured rat aortic SMCs in response to platelet-derived factors was impeded by filter-bound elastin peptides. The inhibitory effect appeared to be relatively specific for elastin peptides and for SMCs, as other matrix components (Types I, III, IV, and V collagens and fibronectin) did not impede SMC migration, and polymorphonuclear leukocytes were not impeded by elastin peptides. Elastin peptides in solution in the lower well caused the migratory response, and this response was also inhibited by filter-bound elastin peptides. Attractants such as platelet-derived factors and elastin peptides are likely to be present in the matrix around migrating SMCs. These studies suggest that elastin peptides adhering to the substratum or elastin, a major component of elastic fiber, may be one of the natural inhibitors of vascular SMC migration in response to chemoattractants in the fluid phase.
Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors (1996)

Some Candida albicans isolates from AIDS patients with oropharyngeal candidiasis are becoming resistant to the azole antifungal agent fluconazole after prolonged treatment with this compound. Most of the C. albicans isolates resistant to fluconazole fail to accumulate this antifungal agent, and this has been considered a cause of resistance. This phenomenon was shown to be linked to an increase in the amounts of mRNA of a C. albicans ABC (ATP-binding cassette) transporter gene called CDR1 and of a gene conferring benomyl resistance (BENr), the product of which belongs to the class of major facilitator multidrug efflux transporters (D. Sanglard, K. Kuchler, F. Ischer, J. L. Pagani, M. Monod, and J. Bille, Antimicrob. Agents Chemother. 39:2378-2386, 1995). To analyze the roles of these multidrug transporters in the efflux of azole antifungal agents, we constructed C. albicans mutants with single and double deletion mutations of the corresponding genes. The mutants were tested for their susceptibilities to these antifungal agents. Our results indicated that the delta cdr1 C. albicans mutant was hypersusceptible to the azole derivatives fluconazole, itraconazole, and ketoconazole, thus showing that the ABC transporter Cdr1 can use these compounds as substrates. The delta cdr1 mutant was also hypersusceptible to other antifungal agents (terbinafine and amorolfine) and to different metabolic inhibitors (cycloheximide, brefeldin A, and fluphenazine). The same mutant was slightly more susceptible than the wild type to nocodazole, cerulenin, and crystal violet but not to amphotericin B, nikkomycin Z, flucytosine, or pradimicin. In contrast, the delta ben mutant was rendered more susceptible only to the mutagen 4-nitroquinoline-N-oxide. However, this mutation increased the susceptibilities of the cells to cycloheximide and cerulenin when the mutation was constructed in a delta cdr1 background. The assay used in the present study could be implemented with new antifungal agents and is a powerful tool for assigning these substances as putative substrates of multidrug transporters.
Microbiology, Pharmacology, and Clinical Use of Mezlocillin Sodium (1982)

The acylureido penicillin mezlocillin is active against gram-positive, gram-negative, and anaerobic bacteria. It easily penetrates the outer membrane of gram-negative bacteria, and it has a strong affinity for penicillin binding protein 3. Its stability to beta-lactamases is weak. Mezlocillin is synergistic when given in combination with aminoglycoside antibiotics. In pharmacokinetic studies mezlocillin conforms to a two compartment open model; its pharmacokinetic properties are dose-dependent. The half-life of the drug is about 1 hour after intravenous injection and 1.5 hours after intramuscular injection. Protein binding ranges from 16 to 42%, and 55% of a dose is excreted in the urine. Biliary excretion ranges from 0.5 to 25%. Clinical trial cure rates were as follows: bacteremia (78%), respiratory tract (62%), urinary tract (81%), gynecological (86%), bone and joint (55%), intraabdominal (67%) and skin and soft tissue (59%). The frequency of adverse reactions was 7.7%. Interstitial nephritis, CNS toxicity, and bleeding have not been reported.
SCENES FROM THE ACS NATIONAL MEETING IN BOSTON (2007)

RETURN TO ISSUEPREVACS NewsNEXTSCENES FROM THE ACS NATIONAL MEETING IN BOSTONLINDA WANG and RUDY M. BAUMCite this: Chem. Eng. News 2007, 85, 37, 40–42Publication Date (Print):September 10, 2007Publication History Published online29 October 2010Published inissue 10 September 2007https://pubs.acs.org/doi/10.1021/cen-v085n037.p040https://doi.org/10.1021/cen-v085n037.p040acs-newsACS PublicationsCopyright © 2007 AMERICAN CHEMICAL SOCIETY. This publication is available under these Terms of Use. This publication is free to access through this site. Learn MoreArticle Views80Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (1 MB) SUBJECTS:Sustainability Get e-Alerts
Formation of Poly(Vinyl Alcohol)/Cationic Starch Blend Nanofibres via the Electrospinning Technique: The Influence of Different Factors (2012)

This paper describes the formation of bicomponent nanofibres from poly(vinyl alcohol) (PVA) and modified cationic starch (CS) mixed solutions (PVA/CS mass ratio 3/1) with different total concentrations of solids in water (8, 10 and 12 wt.%) via the electrospinning technique using two types of rotating electrodes (a plain cylindrical electrode and an electrode with tines). The best results were obtained using a PVA/CS solution with a solid concentration of 8 wt.%. The viscosity of 12 wt. % spinning solution was significantly higher compared to that with a concentration of 8 wt.%. These differences in viscosity had a significant influence on the process of electrospinning, as thinner nanofibres were produced from the less viscous solution. In comparison with the cylindrical electrode, the electrode with tines showed a better performance, where the diameter distribution of nanofibres and the electrospinning process were improved. The purpose of the second part of the experiment was to investigate the influence of different amounts of ethanol in the 8 wt. % PVA/CS solution on the electros-pinning process and the properties of nanofibres. The results showed that 3 wt. % of ethanol in the spinning solution influenced the diameter of nanofibres in comparison with 9 wt.% of ethanol (the diameter of nanofibres significantly increased in this case). Key words: electrospinning, nanofibre, PVA, cationic starch.
P164 Which aspects of stigma are most important in an integrated sexual health service? (2012)

Background The stigma of sexual health services is pervasive and affects all user groups. It is likely to affect access to and satisfaction with the service. Reducing stigma has to be an essential aspect of improving sexual healthcare. Stigma has four domains: disclosure concerns, negative self-image, public attitudes and positive (non-stigmatising) aspects. It is currently not known which of these domains is perceived as most relevant by service users. Objective To determine which aspect of stigma of the service was felt most intensely by service users in a level 3 integrated sexual health service (ISHS). Method Application of a validated 15 item quantitative tool to assess stigma among 200 unselected patients attending an ISHS in outer London. Results A total of 77 strong agreement with a statement describing stigma of the service were recorded. Of them nearly half were given in response to two statements: statement (S) 5: “I am careful whom I tell that I have been in this clinic” (14) and S 10 “I am concerned that I bump into someone I know when I am at this clinic” (16). No other statement attracted &gt;6 positive strong responses. Of the 171 responses indicating a moderate stigma of the service 24 were given to the S1 “I won't tell anyone that I came to this clinic because I am concerned about their reaction”. Statement 5 and S10 received 22 moderate agreements each while S6 “I worry that people who know that I have been here tell others that I have been to this clinic” attracted 17 moderate positive responses. Discussion Our research indicates that disclosure concerns are the key source of stigma for the ISHS. Other aspects like self-image or public attitudes were less relevant. The high level of concerns expressed in S10 throws a new light on the issue of time spent in the waiting room. It suggests that waiting can be very stressful as stigmatising encounters are anticipated.
Relevance feedback (2004)

One of the most important characteristics about relevance feedback is that it ideally finds a set of human perceptually correlated results because the user is directly involved in the search process. In principle, relevance feedback is an iterative learning process where positive and negative examples accumulate as the user gives feedback on each new iteration of results. If we view relevance feedback as a learning problem then we can immediately grasp that there will be the associated problem of learning from a small training set. Towards a solution, we present MediaNet, which is an approach toward integrating additional knowledge sources into the relevance feedback process. The additional knowledge sources are used to shape the learning space when insufficient training samples are available. We also integrate genetic or evolutionary algorithms directly into the search process. Experiments are given on test collections in bio-computing, general photos and video
Rapid Detection and Identification of Respiratory Viruses by Direct Immunofluorescence (1970)

The use of fluorescein-conjugated antiserum against respiratory syncytial (RS) and parainfluenza 1 and 3 viruses was compared with conventional techniques in the rapid detection of virus in tissue cultures inoculated with pharyngeal specimens known to contain these viruses. Twenty-three specimens were tested: 9 RS, 8 parainfluenza 1, and 6 parainfluenza 3. The fluorescent-antibody technique (FA) detected virus in 52% of the tissue cultures in 24 hr, and, by 72 hr, 22 of the 23 cultures were FA-positive whereas only 5 were positive by conventional techniques. Additionally, conjugated antisera were prepared against herpes simplex, influenza A2, and adenovirus type 5. All conjugates stained only the homologous virus and were 100- to 10,000-fold more sensitive than conventional techniques in detecting descending dilutions of virus inocula by 24 hr. With the procedures described, several antisera could be conjugated and ready for use within 24 hr. Serum fractionation was by ammonium sulfate precipitation, and with the procedure outlined virtually complete recovery of the globulin fraction and elimination of all of the albumin were accomplished.
59.1: Invited Paper : LTPS Backplane Technologies for AMLCDs and AMOLEDs (2011)

Abstract In this paper, we review various LTPS backplane technologies based on laser‐crystallization and other related methods that have been applied to AMLCD and AMOLED displays. The TFT performances obtained by different melt‐mediated crystallization methods with excimer laser and solid phase crystallization will be compared. The technical issues of the image quality and the resolution will be discussed.