gebhart/patrepeval huggingface dataset:
Questions de performances et de backups, la suite ... (2018)

A. méliorations des performances (la suite ...) Nous avions terminé notre communication de l'année dernière (MM2017 FR) en évoquant un changement du système de fichiers (GPSG vers CEPH) et un changement de base de données (MySQL vers Percona). Retour d'expérience. B. ackups automatiques (la suite ...) Nous proposons de présenter de nouvelles optimisations de la personnalisation des scripts de backups automatiques que nous avions exposé l'année dernière. Identification des derniers problèmes et accélération de la procédure.
An analysis of COVID-19 vaccine sentiments and opinions on Twitter (2021)

Understanding sentiments and opinions toward vaccination using Twitter may help public health agencies to increase positive messaging and eliminate opposing messages in order to enhance vaccine uptake.
Reducing field-scale emissions of 1,3-D with composted municipal green-waste. (2008)

Summary. A field experiment was conducted to measure subsurface movement and volatilization of the 1,3-dichloropropene (1,3-D) after shank injection to an agricultural soil. Aerodynamic, integrated horizontal flux and theoretical profile shape methods were used to obtain fumigant flux density and cumulative emission values. The volatilization rate was measured continuously for 16 days and the range in the daily peak volatilization rates for the three methods ranged from 4 to 23 µg m-2 s-1. The total 1,3-D mass that volatilized to the atmosphere was approximately 15–36 kg ha-1, or 3–8 % of the applied active ingredient. This represents approximately 10–25 % of the total emissions observed in recent field and laboratory studies. Significant reductions in volatilization of 1,3-D are possible when composted municipal green-waste material is incorporated into the surface soil. Approach. A field experiment was conducted to measure the volatilization rate of 1,3-dichloropropene (1,3-D) after shank injection. 1,3-D has relatively high volatility and water solubility and relatively short field half-life. After fumigation, residual 1,3-D may be detectable in soil for several weeks. There are few published field experiments that measure field-scale emissions of 1,3-D after shank injection. A literature search could not find any reference to
Q-Ary Multi-Mode OFDM With Index Modulation (2020)

In this letter, we propose a novel orthogonal frequency division multiplexing with index modulation (OFDM-IM) scheme, which we call Q -ary multi-mode OFDM-IM (Q -MM-OFDM-IM). In the proposed scheme, Q disjoint M-ary constellations are used repeatedly on each subcarrier, and a maximum-distance separable code is applied to the indices of these constellations to achieve the highest number of index symbols. A low-complexity subcarrier-wise detection is shown possible for the proposed scheme. Spectral efficiency (SE) and the error rate performance of the proposed scheme are further analyzed. It is shown that the proposed scheme exhibits a very flexible structure that is capable of encompassing conventional OFDM as a special case. It is also shown that the proposed scheme is capable of considerably outperforming the other OFDM-IM schemes and conventional OFDM in terms of error and SE performance while preserving a low-complexity structure.
ShopTalk: A System for Conversational Faceted Search (2021)

We present ShopTalk, a multi-turn conversational faceted search system for shopping that is designed to handle large and complex schemas that are beyond the scope of state of the art slot-filling systems. ShopTalk decouples dialog management from fulfillment, thereby allowing the dialog understanding system to be domain-agnostic and not tied to the particular shopping application. The dialog understanding system consists of a deep-learned Contextual Language Understanding module, which interprets user utterances, and a primarily rules-based Dialog-State Tracker (DST), which updates the dialog state and formulates search requests intended for the fulfillment engine. The interface between the two modules consists of a minimal set of domain-agnostic "intent operators," which instruct the DST on how to update the dialog state. ShopTalk was deployed in 2020 on the Google Assistant for Shopping searches.
Characteristics of laminar jet impactors (1974)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCharacteristics of laminar jet impactorsVirgil A. Marple and Benjamin Y. H. LiuCite this: Environ. Sci. Technol. 1974, 8, 7, 648–654Publication Date (Print):July 1, 1974Publication History Published online1 May 2002Published inissue 1 July 1974https://doi.org/10.1021/es60092a003Request reuse permissionsArticle Views1107Altmetric-Citations228LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (710 KB) Get e-Alertsclose Get e-Alerts
Interplay Between Air Travel, Genome Integrity, and COVID-19 Risk vis-a-vis Flight Crew (2020)

During air travel, flight crew (flight attendants, pilots) can be exposed to numerous flight-related environmental DNA damaging agents that may be at the root of an excess risk of cancer and other diseases. This already complex mix of exposures is now joined by SARS-CoV-2, the virus that causes COVID-19. The complex exposures experienced during air travel present a challenge to public health research, but also provide an opportunity to consider new strategies for understanding and countering their health effects. In this article, we focus on threats to genomic integrity that occur during air travel and discuss how these threats and our ability to respond to them may influence the risk of SARS-CoV-2 infection and the development of range of severity of the symptoms. We also discuss how the virus itself may lead to compromised genome integrity. We argue that dauntingly complex public health problems, such as the challenge of protecting flight crews from COVID-19, must be met with interdisciplinary research teams that include epidemiologists, engineers, and mechanistic biologists.
[Balanced facial hydrophilicity of ioversol: a qualitative approach of hydrophilicity]. (1992)

Chimiotoxicity of iodinated contrast media is essentially due to non specific hydrophobic interactions with biologic proteins and membranes. These hydrophobic interactions depend both on the whole molecular lipophilicity and on the spatial accessibility of lipophilic molecular areas. Measurements of lipophilicity by partition coefficient, partially take into account the spatial localisation of hydrophilic groups around the lipophilic area due to the 1,3,5-triiodo-benzene. These measurements have to be completed by an accurate knowledge of the three-dimensional localisation of hydrophilic groups to improve the biocompatibility of polyiodinated contrast media. The concept of evenly distributed facial hydrophilicity aims to minimize the accessibility to lipophilic area by a localisation of hydrophilic group on each plan of the benzene ring. The molecular structure of ioversol allows to put this concept in concrete form thanks to a tertiary anilide group which imposes on one hydroxy group to be located on each face of the 1,3,5-triiodo-benzene ring, providing facial hydrophilic protection.
CO2 Foam Field Trial at North Ward-Estes (1992)

ABSTRACT A CO2 foam field trial was conducted in the North Ward-Estes field in Texas to evaluate the effectiveness of foam in improving CO2 sweep efficiency. This paper describes the design, results, and analysis of foam treatment with emphasis on the design methodology of applying foam in grossly heterogeneous reservoirs, characterized by uneven areal and vertical sweep in most patterns. Over a period of nearly two years, foam was emplaced into an injector four times by alternately injecting CO2 and surfactant solution, and followed by continuous CO2 injection after each emplacement. Foam was generated in situ, which reduced CO2 injectivity by 40 to 85%. Gas production in the problem producer decreased dramatically, while gas and oil production in other offset producers increased, indicating areal diversion. Vertical diversion also occurred, as evidenced by significant increase in oil production in the problem producer, where tertiary oil response had peaked prior to the foam treatment. The field test shows that a properly designed foam treatment can significantly improve the CO2 sweep efficiency and be economically successful. The methodology developed in the design and analysis of the foam test may be applied to other conformance improvement processes.
General In Vitro Method to Analyze the Interactions of Synthetic Polymers with Human Antibody Repertoires (2013)

Recent reports on the hitherto underestimated antigenicity of poly(ethylene glycol) (PEG), which is widely used for pharmaceutical applications, highlight the need for efficient testing of polymer antigenicity and for a better understanding of its molecular origins. With this goal in mind, we have used the phage-display technique to screen large, recombinant antibody repertoires of human origin in vitro for antibodies that bind poly(vinylpyrrolidone) (PVP). PVP is a neutral synthetic polymer of industrial and clinical interest that is also a well-known model antigen in animal studies, thus allowing the comparison of in vitro and in vivo responses. We have identified 44 distinct antibodies that bind specifically to PVP. Competitive binding assays show that the PVP-antibody binding constant is proportional to the polymerization degree of PVP and that specific binding is detected down to the vinylpyrrolidone (VP) monomer level. Statistical analysis of anti-PVP antibody sequences identifies an amino-acid motif that is shared by many phage-display-selected anti-PVP antibodies that are similar to a previously described natural anti-PVP antibody. This suggests a role for this motif in specific antibody/PVP interactions. Interestingly, sequence analysis also suggests that only a single antibody chain containing this shared motif is responsible for antibody binding to PVP, as confirmed upon systematic deletion of either antibody chain for 90% of selected anti-PVP antibodies. Overall, a large number of antibodies in the human repertoires we have screened bind specifically to PVP through a small number of shared amino acid motifs, and preliminary comparison points to significant correlations between the sequences of phage-display-selected anti-PVP antibodies and their natural counterparts isolated from immunized mice in previous studies. This study pioneers the use of antibody phage-display to explore the antigenicity of biotechnologically relevant polymers. It also paves the way for a fast, cost-effective, and systematic in vitro analysis, thus reducing the need for animal immunization experiments. Moreover, identifying the encoding DNA sequence of polymer-binding antibodies via phage-display enables future applications of a molecular biology approach to protein-polymer conjugation, based on protein-antibody fusion.
CIEL*a*b* Measurements to Determine the Role of Felling Season, Log Storage and Kiln Drying on Coloration of Silver Birch Wood (2002)

The effects of felling season, log storage and kiln drying on stemwood discoloration of sixty mature silver birches ( Betula pendula ) were studied and provided with CIEL*a*b* colour coordinates. The colour differences were expressed as j E* including split up of j L*, j a* and j b*. The results showed that fresh wood colour depends on the felling season: light and pale colours were recorded for samples taken from autumn- and winter-felled trees, whereas the colour of fresh wood was considerably darker if the felling took place in the spring or summer. After storage, notable changes in colour were observed. After drying, all samples showed low lightness, moderate redness and relatively high yellowness under the drying conditions used in the study regardless of the felling season or duration of storage. The main colour component responsible for the discoloration was lightness, while chroma values redness and yellowness played a minor role. Keywords: BetulaPendulaDiscolorationSpectrophotometryStemQuality
AKT-pathway Inhibition in Chronic Lymphocytic Leukemia Reveals Response Relationships Defined by TCL1 (2014)

Cell survival in chronic lymphocytic leukemia (CLL) largely depends on B-cell receptor-induced AKT activation. Gain-of-function genomic lesions of PI3K-AKT-mTOR pathway components are usually absent in CLL. We previously established that a BCR-mediated growth response in CLL is determined by the oncogene T-cell leukemia 1 (TCL1) through a sensitizer effect on AKT phospho-activation. Despite high clinical response rates following AKT-cascade inhibition in CLL, resistances in a substantial proportion of patients call for reliable pre- and post-exposure strata to better predict compound responses. Using a panel of inhibitors with differential vertical affinities in the PI3K-AKT-mTOR axis, we describe distinct patterns and determinants of sensitivities in 75 CLL samples. The compounds specifically impacted the BCR-induced physical TCL1-AKT interaction. In general, there was an efficient and tumor-selective abrogation of cell survival in suspension or protective stromal-cell cultures. However, biochemical and survival responses were heterogeneous across CLL and showed only incomplete overlap across inhibitors. Sensitivity clusters could be defined by differential responses to selective pan-PI3K inhibition vs. compounds acting more down-stream. An elevated PI3K/AKT/mTOR activation state conferred sensitivity or resistance, depending on the applied inhibitor. In fact, down-stream interception by mTOR or dual mTOR/PI3K inhibition appears more efficient in cases expressing the BCR-response and poor-risk determinants of ZAP70 or TCL1. Finally, exploiting the TCL1-AKT interaction, peptide-based TCL1-interphase mimics were potent in steric AKT antagonization and in reducing CLL cell survival. Overall, this study provides informative response relationships in AKT-pathway interception that can help refining predictive models in BCR-pathway inhibition in CLL.
Ultra-Low Frequency Dielectric Loss Detection and Aging State Evaluation of 10kV XLPE Cable (2018)

In this paper, the effectiveness of ultra-low frequency dielectric loss in evaluating the insulation aging state of XLPE cables is described. The ultra-low frequency dielectric loss of 21 10kV cables in Tianjin area was measured. On the basis of the analysis of the relationship between the ultra-low frequency dielectric loss and the aging of insulated water branch aging, according the International Society of Electrical Engineers IEEE400.2-2013 IEEE Guide for Field Testing of Shielded Power Cable Systems Using Very Low Frequency(VLF)(less than 1Hz), the test date are analyzed. The results are shown that 9 of the 21 cables are in a state of need for further test or maintenance. The longer the service time, the more cable failures, the more serious the aging degree. The ultra-low frequency dielectric loss can effectively evaluate the insulation aging state of XLPE cables, which is of great significance for guiding the reconstruction of the distribution network cable in Tianjin.
Supplement Table 1 from Auranofin Protects Intestine against Radiation Injury by Modulating p53/p21 Pathway and Radiosensitizes Human Colon Tumor (2023)

&lt;p&gt;mRNA expression of UPR downstream proapoptotic molecule&lt;/p&gt;
Improving Robotic Tactile Localization Super-resolution via Spatiotemporal Continuity Learning and Overlapping Air Chambers (2023)

Human hand has amazing super-resolution ability in sensing the force and position of contact and this ability can be strengthened by practice. Inspired by this, we propose a method for robotic tactile super-resolution enhancement by learning spatiotemporal continuity of contact position and a tactile sensor composed of overlapping air chambers. Each overlapping air chamber is constructed of soft material and seals the barometer inside to mimic adapting receptors of human skin. Each barometer obtains the global receptive field of the contact surface with the pressure propagation in the hyperelastic seal overlapping air chambers. Neural networks with causal convolution are employed to resolve the pressure data sampled by barometers and to predict the contact position. The temporal consistency of spatial position contributes to the accuracy and stability of positioning. We obtain an average super-resolution (SR) factor of over 2500 with only four physical sensing nodes on the rubber surface (0.1 mm in the best case on 38 × 26 mm²), which outperforms the state-of-the-art. The effect of time series length on the location prediction accuracy of causal convolution is quantitatively analyzed in this article. We show that robots can accomplish challenging tasks such as haptic trajectory following, adaptive grasping, and human-robot interaction with the tactile sensor. This research provides new insight into tactile super-resolution sensing and could be beneficial to various applications in the robotics field.
An expert system for the automatic classification and description of zooplanktons from monocular images (2003)

An automatic system to recognize the biological zooplanktons from monocular images is presented. It has two cooperating subsystems: a modular set of algorithm describing the complex shapes and a classification expert system. The results are shown for various examples. The methodology which is developed is independent of the application and is thus a general tool for building complex automatic systems.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
A WDM-based PCN architecture (2002)

A WDM-based PCN architecture is proposed. Based on the broadcast nature of WDM star couplers, this WDM-based architecture gains several advantages over the current prominent ATM-based PCN architecture: (1) a fast hand-off scheme for roaming terminals, (2) an easy multicast routing implementation for mobile environment, and (3) a less number of continuous reconnections. Based on the proposed architecture, a wavelength offset conflict problem might occur when mobile terminals move into neighboring cells. A wavelength assignment scheme is proposed to assign the wavelength and offset on the star coupler for each connection so that the offset conflict rate is kept as small as possible. Simulation results show that the proposed wavelength offset assignment scheme performs much better than the random assignment scheme in terms of offset conflict rate.
Transport properties of CeSb1−xTex for x&lt;0.05 (1982)

Magnetic and transport properties of x = 0, 0.02, and x = 0.05 single crystals have been investigated in the range 3&amp;lt;T&amp;lt;300 K. A decrease of the number of magnetic phases of the Néel temperature TN as a function of x is observed. Elastic plus inelastic magnetic scattering of the carriers by spin fluctuations have been computed, and the electron phonon interaction satisfies the Grüneisen-Bloch law. A fairly good agreement between theory and experiments is observed in the whole range TN&amp;lt;T&amp;lt;300 K, precluding the hypothesis of any significant Kondo effect in this range of temperatures. However, Kondo effects may explain anomalies in the resistivity below 10 K in the x≠0 samples. The crystal field splittings are larger or equal to 50 K in the x≠0 samples compared with 28.5 K in CeSb. These variations of Δ and TN are discussed with respect to the models of the anisotropic exchange interactions in such materials.
ONC201 kills breast cancer cellsin vitroby targeting mitochondria (2018)

We report a novel mechanism of action of ONC201 as a mitochondria-targeting drug in cancer cells. ONC201 was originally identified as a small molecule that induces transcription of TNF-related apoptosis-inducing ligand (TRAIL) and subsequently kills cancer cells by activating TRAIL death receptors. In this study, we examined ONC201 toxicity on multiple human breast and endometrial cancer cell lines. ONC201 attenuated cell viability in all cancer cell lines tested. Unexpectedly, ONC201 toxicity was not dependent on either TRAIL receptors nor caspases. Time-lapse live cell imaging revealed that ONC201 induces cell membrane ballooning followed by rupture, distinct from the morphology of cells undergoing apoptosis. Further investigation found that ONC201 induces phosphorylation of AMP-dependent kinase and ATP loss. Cytotoxicity and ATP depletion were significantly enhanced in the absence of glucose, suggesting that ONC201 targets mitochondrial respiration. Further analysis indicated that ONC201 indirectly inhibits mitochondrial respiration. Confocal and electron microscopic analysis demonstrated that ONC201 triggers mitochondrial structural damage and functional impairment. Moreover, ONC201 decreased mitochondrial DNA (mtDNA). RNAseq analysis revealed that ONC201 suppresses expression of multiple mtDNA-encoded genes and nuclear-encoded mitochondrial genes involved in oxidative phosphorylation and other mitochondrial functions. Importantly, fumarate hydratase deficient cancer cells and multiple cancer cell lines with reduced amounts of mtDNA were resistant to ONC201. These results indicate that cells not dependent on mitochondrial respiration are ONC201-resistant. Our data demonstrate that ONC201 kills cancer cells by disrupting mitochondrial function and further suggests that cancer cells that are dependent on glycolysis will be resistant to ONC201.