gebhart/patrepeval huggingface dataset:
Importance of the route of intravenous glucose delivery to hepatic glucose balance in the conscious dog. (1987)

To assess the importance of the route of glucose delivery in determining net hepatic glucose balance (NHGB) eight conscious overnight-fasted dogs were given glucose via the portal or a peripheral vein. NHGB was measured using the arteriovenous difference technique during a control and two 90-min glucose infusion periods. The sequence of infusions was randomized. Insulin and glucagon were held at constant basal levels using somatostatin and intraportal insulin and glucagon infusions during the control, portal, and peripheral glucose infusion periods (7 +/- 1, 7 +/- 1, 7 +/- 1 microU/ml; 100 +/- 3, 101 +/- 6, 101 +/- 3 pg/ml, respectively). In the three periods the hepatic blood flow, glucose infusion rate, arterial glucose level, hepatic glucose load, arterial-portal glucose difference and NHGB were 37 +/- 1, 34 +/- 1, 32 +/- 3 ml/kg per min; 0 +/- 0, 4.51 +/- 0.57, 4.23 +/- 0.34 mg/kg per min; 101 +/- 5, 200 +/- 15, 217 +/- 13 mg/dl; 28.5 +/- 3.5, 57.2 +/- 6.7, 54.0 +/- 6.4 mg/kg per min; +2 +/- 1, -22 +/- 3, +4 +/- 1 mg/dl; and 2.22 +/- 0.28, -1.41 +/- 0.31, and 0.08 +/- 0.23 mg/kg per min, respectively. Thus when glucose was delivered via a peripheral vein the liver did not take up glucose but when a similar glucose load was delivered intraportally the liver took up 32% (P less than 0.01) of it. In conclusion portal glucose delivery provides a signal important for the normal hepatic-peripheral distribution of a glucose load.
Direct Interaction of a Ca2+-binding Loop of Synaptotagmin with Lipid Bilayers (1998)

Synaptotagmin 1 binds Ca2+ and membranes via its C2A-domain and plays an essential role in excitation-secretion coupling. In this study, we sought to identify Ca2+- and membrane-induced local conformational changes in the C2A-domain of synaptotagmin and to delineate the C2A-lipid binding interface. To address these questions native phenylalanine residues were replaced, at each face of the domain, with tryptophan reporters. Changes in tryptophanyl fluorescence indicated that Ca2+ induced long range conformational changes throughout C2A, including regions distant from an established Ca2+-binding site. Addition of liposomes resulted in Ca2+-dependent increases in the fluorescence of tryptophans 193, 231, and 234. Only the tryptophan residues at positions 234 and 231, which lie within a Ca2+-binding loop of C2A, exhibited liposome-induced blue shifts in their emission spectra. Quenching experiments, using membrane-imbedded doxyl spin labels, revealed that tryptophan residues 231 and 234 penetrated lipid bilayers. These data delineate the lipid binding interface of C2A and provide the first evidence for adjacent Ca2+- and lipid-binding sites within a C2-domain. The penetration of C2A into membranes may function to bring components of the fusion machinery into contact with the lipid bilayer to initiate exocytosis.
Peritoneal lavage cytology findings as prognostic factor for gastric cancer (1999)

The validity of lavage cytology for accurate gastric cancer staging is demonstrated in this study. Between 1988 and 1996, 29 cases (8. 4%) were revealed as positive among 347 patients with resectable gastric cancer in whom peritoneal lavage cytology was performed. The survival rate of cytology-positive patients in each stage was found to be worse than that of all other patients in the same stage. The prognostic factors selected by the univariate analysis were enrolled for multivariate analysis using Cox's proportional hazards model with the backward stepwise procedure. As a result, although cytology finding was selected as an independent prognostic factor, macroscopic finding of dissemination was not selected. Our data indicate that positive cytology findings indicated a poor prognosis, and therefore the results of peritoneal lavage cytology should be included as a factor in gastric cancer staging.
Chemicals used as disinfectants: active ingredients and enhancing additives (1995)

Active ingredients used in microbiocidal products in the European Union constitute some 250 chemical entities. Approximately 100 of these chemicals are commonly used in disinfectant products. The majority of these substances may be classified into distinct chemical groupings. A brief review of the chemical, physical and microbiological properties of each group is given, together with some indications of additives which may be used to enhance their properties, and factors which may detract from them. Some indications of usage areas are given.
Entanglement-assisted concatenated quantum codes (2022)

Entanglement-assisted concatenated quantum codes (EACQCs), constructed by concatenating two quantum codes, are proposed. These EACQCs show significant advantages over standard concatenated quantum codes (CQCs). First, we prove that, unlike standard CQCs, EACQCs can beat the nondegenerate Hamming bound for entanglement-assisted quantum error-correction codes (EAQECCs). Second, we construct families of EACQCs with parameters better than the best-known standard quantum error-correction codes (QECCs) and EAQECCs. Moreover, these EACQCs require very few Einstein-Podolsky-Rosen (EPR) pairs to begin with. Finally, it is shown that EACQCs make entanglement-assisted quantum communication possible, even if the ebits are noisy. Furthermore, EACQCs can outperform CQCs in entanglement fidelity over depolarizing channels if the ebits are less noisy than the qubits. We show that the error-probability threshold of EACQCs is larger than that of CQCs when the error rate of ebits is sufficiently lower than that of qubits. Specifically, we derive a high threshold of 47% when the error probability of the preshared entanglement is 1% to that of qubits.
CAN WE IMPROVE THE CLINICAL UTILITY OF RESPIRATORY RATE AS A MONITORED VITAL SIGN? (2009)

Respiratory rate (RR) is a basic vital sign, measured and monitored throughout a wide spectrum of health care settings, although RR is historically difficult to measure in a reliable fashion. We explore an automated method that computes RR only during intervals of clean, regular, and consistent respiration and investigate its diagnostic use in a retrospective analysis of prehospital trauma casualties. At least 5 s of basic vital signs, including heart rate, RR, and systolic, diastolic, and mean arterial blood pressures, were continuously collected from 326 spontaneously breathing trauma casualties during helicopter transport to a level I trauma center. "Reliable" RR data were identified retrospectively using automated algorithms. The diagnostic performances of reliable versus standard RR were evaluated by calculation of the receiver operating characteristic curves using the maximum-likelihood method and comparison of the summary areas under the receiver operating characteristic curves (AUCs). Respiratory rate shows significant data-reliability differences. For identifying prehospital casualties who subsequently receive a respiratory intervention (hospital intubation or tube thoracotomy), standard RR yields an AUC of 0.59 (95% confidence interval, 0.48-0.69), whereas reliable RR yields an AUC of 0.67 (0.57-0.77), P < 0.05. For identifying casualties subsequently diagnosed with a major hemorrhagic injury and requiring blood transfusion, standard RR yields an AUC of 0.60 (0.49-0.70), whereas reliable RR yields 0.77 (0.67-0.85), P < 0.001. Reliable RR, as determined by an automated algorithm, is a useful parameter for the diagnosis of respiratory pathology and major hemorrhage in a trauma population. It may be a useful input to a wide variety of clinical scores and automated decision-support algorithms.
Selective Formation of C2 Compounds from Electrochemical Reduction of CO2 at a Series of Copper Single Crystal Electrodes (2001)

Electrochemical reduction of CO2 was studied using single-crystal electrodes, Cu(111), Cu(100), Cu(S)-[n(100) × (111)], and Cu(S)-[n(100) × (110)] at a constant current density 5 mA cm-2 in 0.1 M KHCO3 aqueous solution. Copper single crystals were prepared from 99.999% copper metal in graphite crucibles by the Bridgeman method. The crystal orientation was determined by the X-ray back reflection method. The Cu(111) electrode yields mainly CH4 from CO2, and the Cu(100) favorably gives C2H4. Introduction of (111) steps to Cu(100) basal plane, leading to Cu(S)-[n(100) × (111)] orientations, significantly promoted C2H4 formation and suppressed CH4 formation. The selectivity ratio C2H4/CH4 on Cu(711) (n = 4) amounted to 14, 2 orders of magnitude higher than that on Cu(111).
Asphaltene Separation with Designer Solvents for the Deasphaltenes Process-A Quantum Chemical Approach (2016)

Significance of Ionic Liquids (ILs), designer solvents, on inhibiting the asphaltene deposition provided the alternative solution to the problem. In this work, 34 anions and 3 cations comprising of 102 combinations of ILs were investigated for a model asphaltene molecule via quantum solvation software tool COSMO-RS (Conductor like Screening for Real Solvents). Validation is done by comparing literature values of activity coefficient at infinite dilution (IDAC) of alkanes, cycloalkanes and aromatic in 3 ILs with 111 data points at 3 sets of different temperatures. Percent relative absolute average deviation (%RAAD) was found to be 10%. Thereafter IDAC values were predicted for model asphaltene compound in the cations and anions combinations for performance analysis. It is found that smaller cation with sterically shielded large anion gave the large performance for removal of upgrading the asphaltenic crude oil.
Emission control of NV centers embedded in an opal photonic crystal (2009)

We investigate emission of diamond nanocrystals containing nitrogen-vacancy (NV) centers within opal photonic crystals (PC). The PC exhibits a stopband that overlaps the NV photoluminescence spectrum. A modified emission spectrum and increased lifetime were measured.
Refrigerant Subcooling Correlations for Different Expansion Devices for a Non-Intrusive Charge Indicator (2006)

The most common problems affecting residential and light commercial heating, ventilation, and air-conditioning (HVAC) systems are slow refrigerant leaks. Equipment users are usually not aware of the problem until most of the refrigerant has escaped. A low-cost, non-intrusive refrigerant charge indicator has been developed, based on temperature measurements and correlations formed to interpret the measured temperatures. It can be used to provide real time warnings to the equipment users before the majority of refrigerant is escaped. It could be inexpensive and easy to incorporate into existing heat pumps and air conditioners. Extensive laboratory experimental work was performed on a 2-ton window air conditioner and on a 2.5 ton split heat pump system. It was found that the heat pump was not sensitive to slow refrigerant leak because of the long liquid line. Liquid subcooling was measured to determine the system charge status before a substantial amount of refrigerant was leaked. This study reports the finding of correlations formed for liquid subcooling for the orifice plate and thermal expansion valve used on the heat pump system for both heating and cooling mode operation.
Systematics of South American Tripsacum (Gramineae) (1981)

The genus Tripsacum is widely distributed between 42°N and 24°S latitude. In South America, the genus extends around the Amazon and Orinoco basin, and from the Caribbean coast south to Brazil and Paraguay. The most common South American taxon is T. dactyloides (L.) L. var. meridonale de Wet and Timothy (2n = 36), which differs from North American representatives of the species in having subdigitate recemes usually appressed with the apical male sections typically curved. Closely related to T. dactyloides, but usually occupying more seasonally moist and dry habitats, is T. australe Cutler and Anderson. This species is typically robust with the basal leaf sheaths tomentose, and the much elongated culms becoming decumbent in older plants. Smaller plants, with essentially erect culms and leaf sheaths on the culms hirsute rather than tomentose, are recognized as T. australe var. hirsutum de Wet and Timothy. The two varieties of T. australe are both diploid (2n = 36) and they cross to produce fertile hybrids. They also cross with T. dactyloides var. meridonale (2n = 36), but these hybrids are partially sterile. Tripsacum cundinamarce de Wet and Timothy (2n = 36) is a robust species with glaucus leaves. It resembles robust specimens of T. dactyloides in having glabrous leaf sheaths, but can always be recognized by inflorescences that are composed of racemes arranged along a several-noded primary axis. This species is confined to moist habitats, while T. dactyloides occupies a range of habitats in South America. Tripsacum peruvianum de Wet and Timothy is a gametophytic apomict with 2n = 72, 90 or 108 chromosomes. It is characterized by an erect growth habit and strongly hirsute leaf sheaths. The cultivated Guatemala grass, T. andersonii Gray, occurs spontaneously in the mountains of Venezuela, Colombia, and Peru. This sexually sterile species is characterized by 2n = 64, and may combine 54 Tripsacum and 10 Zea chromosomes in its genome. Electrophoretic patterns of seed storage proteins confirm the validity of recognizing T. cundinamarce as distinct from T. dactyloides, and T. peruvianum as distinct from T. australe.
Deterioration of Synthetic Fiber Rope during Marine Usage. Appendix A. (1981)

Abstract : This document lists reports on the deterioration of synthetic fiber rope during marine usage.
Living on the rocks: substrate mineralogy and the structure of subtidal rocky substrate communities in the Mediterranean Sea (2004)

Distribution patterns of epibenthic assemblages, sea urchins and fishes were assessed in NE Sardinia (Mediterranean Sea) in shallow (4 to 7 m depth) rocky habitats with 2 rock-type substrates, i.e. limestone and granite, to examine possible differences related to the mineralogical composition of rocks. Sessile organisms and sea urchins were sampled in situ within quadrats. Fishes were assessed by visual census transects. Sessile epibenthic assemblages significantly differed between granite and limestone substrates, and the number of epibenthic sessile taxa was greater on limestone. Average cover of the algae mat (unidentified mixture of filamentous and mucilaginous algae) was significantly greater on granite than limestone, while no significant differences were detected in total cover or in the average cover of the remaining most common epibenthic taxa. Densities of sea urchins (i.e. Paracentrotus lividus and Arbacia lixula) did not differ between the 2 rock types. Fish assemblages were significantly different between granite and limestone rock substrates. Labrids of the genus Symphodus and Serranus scriba were more abundant on granite, whereas Serranus cabrilla, Parablennius rouxi, Gobius bucchichi and Thalassoma pavo showed greater densities on limestone. Sarpa salpa (the most important herbivorous fish in the Mediterranean sublittoral) did not show any significant difference between granite and limestone substrates. These results suggest that rock type may have the potential to influence marine assemblages, probably through direct effects on epibenthic organisms (e.g. the presence of quartz and substrate texture, both related to the mineralogical features of rocks), and indirect effects on fishes (e.g. the influence of the structure of the epibenthic cover). These results suggest a possible role of the mineralogical composition of rocks in 'bottom-up' processes influencing marine assemblages in shallow sublittoral rocky habitats in the Mediterranean, where direct effects on sessile organisms (e.g. macroalgae) may cascade up through the entire community and affect higher trophic levels (e.g. carnivorous fishes). However, extensive experimental work is needed before drawing any conclusion about the specific processes determining the patterns we observed.
Design and development of the self-assemble Cu-Fe base composites (2005)

The Cu-Fe base alloys with liquid immiscible were prepared by gas atomization technique and conventional solidification process, the self-assemble composite microstructures in powders and bulk materials can be obtained under gravity conditions, respectively, and the minor liquid phase always forms the center of composite microstructure. It is shown that the formation of the core-type macroscopic morphology is strongly connected with the existence of a stable miscibility gap of the liquid phase in the Cu-Fe base alloys. This result can be explained by a mechanism that the minor droplets as the second phase are forced to move into the thermal center due to Marangoni motion, which is caused by the temperature dependence of interfacial energy between two liquid phases.
Facile Synthesis of Iridium Nanocrystals with Well-Controlled Facets Using Seed-Mediated Growth (2014)

Iridium nanoparticles have only been reported with roughly spherical shapes and sizes of 1-5 nm, making it impossible to investigate their facet-dependent catalytic properties. Here we report for the first time a simple method based on seed-mediated growth for the facile synthesis of Ir nanocrystals with well-controlled facets. The essence of this approach is to coat an ultrathin conformal shell of Ir on a Pd seed with a well-defined shape at a relatively high temperature to ensure fast surface diffusion. In this way, the facets on the initial Pd seed are faithfully replicated in the resultant Pd@Ir core-shell nanocrystal. With 6 nm Pd cubes and octahedra encased by {100} and {111} facets, respectively, as the seeds, we have successfully generated Pd@Ir cubes and octahedra covered by Ir{100} and Ir{111} facets. The Pd@Ir cubes showed higher H2 selectivity (31.8% vs 8.9%) toward the decomposition of hydrazine compared with Pd@Ir octahedra with roughly the same size.
Vertically Aligned Lithiophilic CuO Nanosheets on a Cu Collector to Stabilize Lithium Deposition for Lithium Metal Batteries (2018)

Abstract Uncontrollable dendrite growth hinders the direct use of a lithium metal anode in batteries, even though it has the highest energy density of all anode materials. Achieving uniform lithium deposition is the key to solving this problem, but it is hard to be realized on a planar electrode surface. In this study, a thin lithiophilic layer consisting of vertically aligned CuO nanosheets directly grown on a planar Cu current collector is prepared by a simple wet chemical reaction. The lithiophilic nature of the CuO nanosheets reduces the polarization of the electrode, ensuring uniform Li nucleation and continuous smooth Li plating, which is difficult to realize on the normally used lithiophobic Cu current collector surface. The integration of the grown CuO arrays and the Cu current collector guarantees good electron transfer, and moreover, the vertically aligned channels between the CuO nanosheets guarantee fast ion diffusion and reduce the local current density. As a result, a high Columbic efficiency of 94% for 180 cycles at a current density of 1 mA cm −2 and a prolonged lifespan of a symmetrical cell (700 h at 0.5 mA cm −2 ) can be easily achieved, showing a simple but effective way to realize Li metal‐based anode stabilization.
Assessment of Minimal Residual Disease (MRD) by Qualitative RT-PCR (Q-PCR) vs Real-Time Quantitative RT-PCR (RQ-PCR) in a Phase II Study of Acute Promyelocytic Leukemia (APL). (2005)

Abstract Assessment of MRD in APL by Q-PCR analysis for the presence or absence of PML-RARα mRNA after the completion of consolidation therapy in treatment regimens employing all-trans retinoic acid (ATRA) and chemotherapy (CT) has provided a reasonably accurate but not infallible prognostic test for disease recurrence (DR). This assessment has been made at detection sensitivity levels up to 1 in 104, which is considered to have optimal predictive value, since non-quantified lower levels of PML-RARα mRNA may not be relevant to clinical outcome. In the current study, we compared the results of Q-PCR (touchdown PCR for 40 cycles followed by post-PCR blot hybridization with a RARα chemiluminescent probe) to results from RQ-PCR in 15 patients on a Phase II clinical trial designed to eliminate CT (low-risk/LR patients, WBC &lt;10K) or minimize CT (high-risk/HR patients, WBC &gt;10K), using combined ATRA and arsenic trioxide therapy. All patients achieved complete remission (CR) and have been followed for a median of 1.2 years. DR occurred in 0/8 LR, 0/1 unclassified and 2/6 HR patients. At CR, all Q-PCR and RQ-PCR assays were positive. For RQ-PCR, the normalized quotient (NQ) value of PML-RARα, i.e., the PML-RARα copy number divided by the housekeeping gene glyceraldehyde-3′-phosphate dehydrogenase (GAPDH) copy number, ranged widely from 1.5 x 10−6 to 7.0 x 10−3. Post-CR follow-up data were: Patient Group Number Q-PCR+ RQ-PCR+ NQ Range LR/Unclassified 9 0/24 16/24 9 x 10−9 – 1 x 10−7 HR/no DR 4 0/23 8/23 2 x 10−9 – 3 x 10−7 HR/DR 2 1/7 5/7 1 x 10−8 – 5 x 10−5 For the 2 HR/DR patients, the last pre-DR results were, respectively: Q-PCR, positive and negative; RQ-PCR, NQ = 5 x 10−5 and NQ = 2.3 x 10−7. In overall comparisons to RQ-PCR results, all Q-PCR assays were positive for NQ &gt;10−5, 3/4 were positive in the NQ 10−6 to 10−5 range, and all were negative for NQ &lt;10−6. Additionally, dilution-reconstruction experiments confirmed the stochastic nature of PCR assays near the detection limit and indicated that RQ-PCR was about 10-fold more sensitive than Q-PCR. Although larger studies are needed, our results suggest that HR patients who are Q-PCR-negative but RQ-PCR-positive in the &gt;10−7 – &lt;10−5 range at a critical post-CR checkpoint may be at increased risk of DR and, more generally, they suggest that the results of RQ-PCR testing at a critical checkpoint can be used in combination with clinical risk assessment to stratify the intensity of subsequent MRD monitoring in individual patients.
Sphericity and Roundness of Sand in Coastal Plain Soils and Relationships with Soil Physical Properties (1987)

Abstract Sand grain roundness and sphericity were evaluated for 50 soil samples from Atlantic Coastal Plain soils to determine relationships of sand grain roundness and sphericity to the soils' cone index (mechanical impedance), bulk density, and the dense soil angle of repose. A previous investigation collected undisturbed cores from 50 tillage‐induced pans in the Atlantic Coastal Plain, and determined cone index, bulk density, and the dense soil angle of repose. One hundred sand grains were isolated from each of the 50 soil materials. Roundness was determined for each grain by comparing the grain's projected image to standard images in published roundness charts. Sphericity was also determined for the 100 grains per soil by measuring selected grain axes. Mean values for roundness and sphericity were determined for each soil sample. Mean roundness values ranged from 0.44 to 0.57 across sites, but 74% of the sites had mean roundness values between 0.45 and 0.49 inclusive. Mean sphericity values ranged from 0.74 to 0.81, but 72% of the sites had mean sphericities between 0.78 and 0.81 inclusive. Correlation coefficients for relations of cone index, bulk density, and dense soil angle of repose to roundness and sphericity were generally ≤0.26 and not significant (0.10 level). Sphericity and roundness were not significant variables in regression models describing variations in cone index and the dense soil angle of repose. Roundness was not a significant variable in regression models describing variations in bulk density among sites, but sphericity was a significant variable in models that were based on particle size characteristics alone.