gebhart/patrepeval huggingface dataset:
Impact of statin withdrawal on perceived and objective muscle function (2023)

This study is registered in clinicaltrials.gov (NCT01493648).
Supplementary Data from Inhibition of GSK-3 Induces Differentiation and Impaired Glucose Metabolism in Renal Cancer (2023)

&lt;p&gt;The Supplementary Information includes kinase profile of 9-ING-41; IC50 values of 9-ING-41 and Staurosporine in selected eleven kinases and physicochemical properties, biological activity, PK parameters and preliminary ADME/Tox profile for 9-ING-41.&lt;/p&gt;
Hydrotreating the bitumen-derived hydrocarbon liquid produced in a fluidized-bed pyrolysis reactor (1991)

The pyrolysis of bitumen-impregnated sandstone produces three primary product streams: C{sub 1}-C{sub 4} hydrocarbons gases, a C{sub 5}{sup +} total liquid product, and a carbonaceous residue on the spent sand. The bitumen-derived hydrocarbon liquid was significantly upgraded relative to the native bitumen: it had a higher API gravity, lower Conradson carbon residue, asphaltene content, pour point and viscosity and a reduced distillation endpoint relative to the native bitumen. The elemental composition was little different from that of the native bitumen except for the hydrogen content which was lower. The bitumen-derived liquid produced in a 4-inch diameter fluidized-bed reactor from the Whiterocks tar sand deposit has been hydrotreated in a fixed-bed reactor to determine the extent of upgrading as a function of process operating variables. The extent of denitrogenation and desulfurization of the bitumen-derived liquid was used to monitor catalyst activity as a function of process operating variables and to estimate the extent of catalyst deactivation as a function of time on-stream. The apparent kinetics for the nitrogen and sulfur removal reactions were determined. Product distribution and yield data were also obtained.
Comparative study of eight cubic equations of state for predicting thermodynamic properties of alkanes (2011)

Abstract Precise descriptions of the thermodynamic properties of pure fluids require accurate definition of vapour–pressure and phase volumes as well as residual volumes, enthalpies and entropies. While carefully fitted multi‐parameter equations of state (EOS), such as Benedict–Webb–Rubin–Starling fulfil these requirements, cubic EOSs usually do not. On the other hand, cubic EOSs are widely used in the oil industry, due to their simplicity and reliability in most vapour–liquid equilibrium calculations. For thermal oil recovery processes and the natural gas industry, the choice of EOS becomes important for predicting thermodynamic properties, such as isobaric and isochoric heat capacities, sound velocity and the Joule–Thomson coefficient. In this study, eight cubic EOSs which most of them are used in commercial reservoir simulators are selected for evaluation of their capability in the prediction of second‐order derivative thermodynamic properties at different temperatures and pressures, using pure components frequently found in petroleum and natural gas mixtures. It is shown that none of the cubic EOSs could accurately predict all of the stated parameters, especially below the critical point. All EOSs failed to show the extrema in the derivative properties. However, among these equations the Yu–Lu and Schmidt–Wenzel EOSs were found to have more reliable predictions in most of the cases. © 2011 Canadian Society for Chemical Engineering
Self‐Assembly of PEG and Diester Copolymers: Effect of PEG Length, Linker, Concentration and Temperature (2005)

The formation of micelles in a solvent that is selective for one of the blocks is one of the most important and useful properties of block copolymers. Recently, we have synthesized copolymers of polyethylene glycol and various dimethyl esters, which self‐assemble into nano micellar aggregates in aqueous media. These nano micelles are very effective in solubilizing otherwise insoluble drugs. The structure, interaction and size of these nano micelles are very important and critical to design an efficient drug delivery system. In the present work, we have studied the effect of hydrophilic block, PEG length, linker, concentration and temperature on these nano micellar structures and interactions by static light scattering techniques.
Regioselective C–H Sulfanylation of Aryl Sulfoxides by Means of Pummerer-Type Activation (2017)

A regioselective C-H sulfanylation of aryl sulfoxides with alkyl aryl sulfides in the presence of acid anhydride was developed, which resulted in the formation of 1,4-disulfanylarenes after dealkylation of initially formed sulfonium salts. The reaction began with Pummerer-type activation of aryl sulfoxides followed by nucleophilic attack of alkyl aryl sulfides. The nucleophilic attack occurred exclusively at the para positions, or at specific positions in case the para position was not available, under perfect control by the dominating sulfoxide directors regardless of any other substituents. The initially formed aryl sulfonium salts were isolable and usefully served as aryl halide surrogates for palladium-catalyzed arylation with sodium tetraarylborates.
Reactive power optimization using repeated genetic algorithm and data prediction (2013)

This paper gives 3000 solutions for reactive power optimization using repeated genetic algorithm. The objective function is minimization of voltage deviations at load buses and the control actions are changes in generator excitations, capacitor switching and tap changing transformers. IEEE30 bus system is the test data and simulated on MATLAB. New data prediction algorithm is given.
Sugar Transformations Using Enzymes in Non-Aqueous Media (2000)

The peculiar properties of enzymes, especially high selectivity and mild reaction conditions, have boosted their popularity among organic chemists. These biocatalysts appear to be particularly suitable to support natural products synthesis and, more specifically, carbohydrate modification [1]. In fact, the presence of several stereogenic carbons as well as the similar chemical reactivity of the numerous hydroxy groups of the sugar molecules still make the transformation of these compounds a challenging target.
Performance comparison of wireless sensor network standard protocols in an aerospace environment: ISA100.11a and ZigBee Pro (2012)

Standards-based wireless sensor network (WSN) protocols are promising candidates for spacecraft avionic systems, offering unprecedented instrumentation flexibility and expandability. However, when migrating from wired to wireless data gathering systems, ensuring reliable data transport is a key consideration. In this paper, we conduct a rigorous laboratory analysis of the relative performance of the ZigBee Pro and ISA100.11a protocols in a representative crewed aerospace environment. Since both operate in the 2.4 GHz radio frequency (RF) band shared by systems such as Wi-Fi, they are subject at times to potentially debilitating RF interference. We compare message delivery rates achievable by both under varying levels of 802.11g Wi-Fi traffic. We conclude that while the simpler, more inexpensive ZigBee Pro protocol performs well under moderate levels of interference, the more complex and costly ISA100.11a protocol is needed to ensure reliable data delivery under heavier interference. This paper represents the first published, rigorous analysis of WSN protocols in an aerospace analog environment of which we are aware and the first published head-to-head comparison of ZigBee Pro and ISA100.11a.
Lifetime prevalence of mental disorders among Asian Americans: Nativity, gender, and sociodemographic correlates. (2014)

This study examines lifetime prevalence estimates of mental disorders among Asian Americans with a focus on differences by nativity, gender, and other relevant sociodemographic correlates. We analyze cross-sectional data from the National Latino and Asian American Study (NLAAS), the first national epidemiological survey of Asian Americans which used a probability sample of household resident adults in the United States (N=2,095). US-born Asian Americans are more likely to experience lifetime mood disorders, substance use disorders, and any mental disorders compared to immigrants. Lifetime substance use disorders are more likely to occur among men rather than women. Nativity and gender show joint associations with different mental disorders: US-born women are at the greatest risk for any mood disorders; US-born men are at the greatest risk for any substance use disorders; and immigrant women are at the lowest risk for substance use disorders compared to all other groups. Analysis of the sociodemographic correlates reveals that the youngest immigrant women showed significantly higher rates of any mood disorder compared to other immigrant women. Additionally, among immigrant men, those with low household income are at a higher risk for mood disorders, and those who report fair/poor English proficiency have a higher prevalence of anxiety and mood disorders. This study provides documentation of prevalence differences in detailed mental health categories along salient axes of stratification among Asian Americans and provides a foundation for future research aimed at understanding the causes and correlates of mental health disparities.
INCREASING THE EFFICIENCY OF SEMICONDUCTOR THERMOCOUPLES (1956)

Abstract : A method of increasing the ratio of carrier mobility to lattice thermoconductivity is given.
ChemInform Abstract: Stereoselective Preparation of Indoloquinolizidine N‐Oxides: Predominant Conformations. (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Determining factors hindering the acceptability of academia-industry collaboration in aided colleges: A case of “managerial skills for entrepreneurs” program (2013)

Academia and Industry have different meaning for the term ‘collaboration’. When collaboration is realized, academicians and students reach the knowledge in practice. It becomes important for one more reason that students from colleges and universities join industry after completing their education. That is why it is essential to have knowledge and interaction with industry. In turn, collaboration with universities is crucial for organizations in order to get solutions for different problems in the form of projects and to get specific industry trained human resource. According to enterprises, the level of success of academia-industry collaboration is evaluated by the measurement of business financial acquisitions and the rate of transfer of new scientific-based knowledge and technology that contributes to the work results. Both parties should collaborate with the aim of fulfilling their objectives. They may launch certain programs for the students. A program with strong curriculum, methods and technology can add value to this collaboration. The success of these programs depends on how students perceive and understand the program's relevance. These kinds of programs may get different response in different type of educational institutions. Professional colleges may easily understand the essence and join them but the scenario in aided colleges is totally different.The objective of the paper is to identify the hindrances in accepting academia-industry collaborated programs by the students. The study reveals that there exists a large variety of potential motivations for accepting these programs. But challenges are more. Students’ decision of joining these programs is affected by many factors like educational, psychological and social that restricts them to accept this outcome of academia-industry collaboration. The study is useful for the academicians, especially of the aided colleges for understanding the challenges to overcome. On the other side it will help the industry in drafting their strategy to make the program popular and their easy entry to the colleges providing traditional degrees. Besides this, the study may be useful for government in changing their rules and regulations and for the society which is ready for the development.
[Chronic myeloid leukemia as a model for modern noncytostatic therapy of malignant diseases. From Virchow to STI 571]. (2002)

Chronic myelogenous leukemia (CML) has been described in the middle of the 19th century. It took further 100 years to the time of the discovery of the first cytotoxic drugs. Ph1 chromosome, the cytogenetic hallmark of CML, has been described in 1960, however, the majority of important discoveries on the molecular level has been done in the 1980s' and later. The chromosomal translocation t(9;22)(q34;q11) is absolutely crucial for CML and leads to the chimeric gene and protein BCR-ABL. The ABL protein possesses the tyrosine kinase activity, which is deregulated in the BCR-ABL protein, leading to the cascade of further pathological processes in the leukemic cells and causing eventually their malignant transformation. In the 1990s, the drug STI 571 has been synthesized, which is a potent inhibitor of the ABL tyrosine kinase activity. The data so far published concerning clinical effects of STI 571 are remarkable and very encouraging. The drug seems to be very safe and has only limited toxicity. It must be emphasized, however, that STI 571 has been clinically tested only since 1998. Moreover, from the mechanisms of action it is clear, that STI 571 influences the secondary, not the primary cause of the CML. Nevertheless, it is without any doubts that the development of new anti-cancer drugs will be done on this non-cytotoxic principle.
Quality of meta-analyses for randomized trials in the field of hypertension (2016)

Although widespread, deficiencies in hypertension-related meta-analyses are readily corrected and do not represent flaws inherent in the meta-analytic method.
Comblike Oligosiloxanes with Higher N ‐Alkyl Substituents — A Basis for Lubricants of the New Century (2005)

A procedure for α-olefin polyaddition to oligohydridosiloxanes was developed and a series of comblike oligoorganosiloxanes of general formula R3SiO(R'2SiO)m[R'R″SiO]nSiR3 where R, R' = CH3, C2H5; R″ = C8H17, C18H37; m = 6, 7; n = 2, 6, 10, 19 with static dimethyl(diethyl)- and methyl(ethyl)alkylsiloxane units distributed in a molecule chain were synthesized. Physical, chemical and Theological properties of the oligomers obtained are presented and their lubricity characteristics (wear spot diameter and critical seizure load) were thoroughly analyzed in comparison with organosilicon fluids and mineral oil.
Suppressing Crossover in Nonaqueous Redox Flow Batteries with Polyethylene-Based Anion-Exchange Membranes (2022)

Redox flow batteries (RFBs) are a promising solution to grid-scale energy storage that utilize solvated redox-active species to store charge. These electrolytes are flowed over stationary electrodes during charge and discharge cycling. However, solubilizing the charge storage species allows for their crossover through the separating membrane, causing electrolyte mixing, and leads to capacity fade and battery failure. Herein, we employ a series of trimethylammonium-functionalized polyethylene membranes in RFB cells to address membrane swelling in organic solvent while maintaining high counterion (PF6–) conduction. We show unprecedented results with 99.99% average capacity retention per cycle and 88% total capacity retention through 1000 charge/discharge cycles with low crossover, as compared to a commercial membrane often used in nonaqueous RFB (NARFB) studies which retained 36% capacity. Our results represent a critical step in developing and understanding anion-exchange membranes (AEMs) as separators for NARFBs and other electrochemical systems employing organic solvents.
Spectroradiometry by Means of Modified Spectrophotometers (1963)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text Harry K. Hammond, "Spectroradiometry by Means of Modified Spectrophotometers," Appl. Opt. 2, 1207_1-1208 (1963) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
The Pregnant Motor Vehicle Accident Casualty (2012)

Rivkind, Avraham I. MD, FACS; Mintz, Yoav MD; Zamir, Gideon MD; Bala, Miklosh MD; Almogy, Gidon MD; Pikarsky, Alon J. MD; Faroja, Mohammad MD; Weiss, Yoram MD Author Information
VON WILLEBRAND FACTORANDVON WILLEBRAND DISEASE (2001)

von Willebrand disease (vWD) is caused by quantitative and/or qualitative defects of the von Willebrand factor (vWF), a multimeric high molecular weight glycoprotein. Typically, it affects the primary hemostatic system, which results in a mucocutaneous bleeding tendency simulating a platelet function defect. The vWF promotes its function in two ways: (i) by initiating platelet adhesion to the injured vessel wall under conditions of high shear forces, and (ii) by its carrier function for factor VIII in plasma. Accumulating knowledge of the different clinical phenotypes and the pathophysiological basis of the disease translated into a classification that differentiated between quantitative and qualitative defects by means of quantitative and functional parameters, and by analyzing the electrophoretic pattern of vWF multimers. The advent of molecular techniques provided the opportunity for conducting genotype-phenotype studies which have recently helped, not only to elucidate or confirm important functions of vWF and its steps in post-translational processing, but also many disease causing defects. Acquired von Willebrand syndrome (avWS) has gained more attention during the recent years. An international registry was published and recommendation by the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis in 2000. It concluded that avWS, although not a frequent disease, is nevertheless probably underdiagnosed. This should be addressed in future prospective studies. The aim of treatment is the correction of the impaired hemostatic system of the patient, ideally including the defects of both primary and secondary hemostasis. Desmopressin is the treatment of choice in about 70% of patients, mostly with type 1, while the others merit treatment with concentrates containing vWF.
Our Country (1964)

Book Review| October 01 1964 Our Country Our Country, Josiah Strong and Jurgen Herbst. William Mulder William Mulder Search for other works by this author on: This Site Google Utah Historical Quarterly (1964) 32 (4): 399–400. https://doi.org/10.2307/45058447 Cite Icon Cite Share Icon Share Facebook Twitter LinkedIn MailTo Permissions Search Site Citation William Mulder; Our Country. Utah Historical Quarterly 1 January 1964; 32 (4): 399–400. doi: https://doi.org/10.2307/45058447 Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All Scholarly Publishing CollectiveUniversity of Illinois PressUtah Historical Quarterly Search Advanced Search The text of this article is only available as a PDF. Copyright 1964, Utah State Historical Society Article PDF first page preview Close Modal You do not currently have access to this content.
Meis1 programs transcription of FLT3 and cancer stem cell character, using a mechanism that requires interaction with Pbx and a novel function of the Meis1 C-terminus (2005)

Meis1 is a homeodomain transcription factor coexpressed with Hoxa9 in most human acute myeloid leukemias (AMLs). In mouse models of leukemia produced by Hoxa9, Meis1 accelerates leukemogenesis. Because Hoxa9 immortalizes myeloid progenitors in the absence of Meis1 expression, the contribution of Meis1 toward leukemia remains unclear. Here, we describe a cultured progenitor model in which Meis1 programs leukemogenicity. Progenitors immortalized by Hoxa9 in culture are myeloid-lineage restricted and only infrequently caused leukemia after more than 250 days. Coexpressed Meis1 programmed rapid AML-initiating character, maintained multipotent progenitor potential, and induced expression of genes associated with short-term hematopoietic stem cells (HSCs), such as FLT3 and CD34, whose expression also characterizes the leukemia-initiating stem cells of human AML. Meis1 leukemogenesis functions required binding to Pbx, binding to DNA, and a conserved function of its C-terminal tail. We hypothesize that Meis1 is required for the homing and survival of leukemic progenitors within their hematopoietic niches, functions mediated by HSC-specific genes such as CD34 and Fms-like tyrosine kinase 3 (FLT3), respectively. This is the first example of a transcription factor oncoprotein (Meis1) that establishes expression of a tyrosine kinase oncoprotein (FLT3), and explains their coexpression in human leukemia. This cultured progenitor model will be useful to define the genetic basis of leukemogenesis involving Hoxa9 and Meis1.
Effect of Computational Constraints on Zero-Dimensional Computations for the Nanosecond-Order Ignition Process of the CH4/Air Mixture (2021)

Abstract Zero-dimensional computations of nanosecond-order ignition using a nanosecond discharge are performed with two constraints. The effects of these constraints are assessed to study the experimental rapid pressure change properly at the initial stages. The computations are carried out with the following constraints: constant internal energy and volume (U&amp;V) and constant enthalpy and pressure (H&amp;P), revealing differences between the two solutions. As the pressure remains constant under the H&amp;P constraint, the total number density of all species decreases during ignition. In this case, O radicals are less generated and consumed. The progression of all reactions and temperatures increases under the H&amp;P constraint less intensely than under the U&amp;V constraint. Significant differences are found between the results calculated under the U&amp;V and H&amp;P constraints. Therefore, large discrepancies with real phenomena can be caused if the loss due to pressure reduction is not treated well.
Magnetoelastic Phenomena in Amorphous Alloys (1976)

Vibrating‐reed measurements have been used to study the amorphous alloys Fe75P15C10 and Fe40Ni40P14B6. The ΔE‐effect is enhanced to large values by stress‐relief anneals, and can be increased even further in a selected direction by magnetic annealing. The maximum ΔE‐effect so far observed (0.8) is thought to be close to the theoretical limit. The temperature dependence of the ΔE‐effect contrasts markedly with that seen in crystalline Ni, a result explained by the absence of magnetocrystalline anisotropy in the amorphous alloys. In addition to the ΔE‐effect, vibrating reeds are shown to be subject to another type of magnetoelastic effect, termed the pole‐effect, which can be used to determine the temperature dependence of the reduced magnetization. The kinetics of thermally activated atomic movement have been studied both by internal friction measurements and by magnetic annealing experiments. In both alloys the activation energy for magnetic annealing is found to be only about one‐half of that for stress‐induced ordering.
ChemInform Abstract: Dendrimer‐Encapsulated Metal Nanoparticles: Synthesis, Characterization, and Applications to Catalysis (2001)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.