gebhart/patrepeval huggingface dataset:
The Osteocalcin Gene Promoter Provides a Molecular Blueprint for Regulatory Mechanisms Controlling Bone Tissue Formation: Role of Transcription Factors Involved in Development (1996)

Characterization of regulatory sequences and their cognate binding factors in the bone-specific osteocalcin (OC) gene promoter has provided insight into mechanisms that control expression of the gene under diverse biological conditions. We present evidence for AP-1 motifs and two multipartite conserved regulatory sequences, the OC Box I (nt-99 to-76) and a site designated OC Box II (nt-136 to-130) in contributing to developmental and tissue-specific expression of osteocalcin. OC Box I is characterized by a homeodomain binding site and OC Box II is a recognition sequence for AML-1 (also called PEBP2 alpha), a runt homology-related DNA binding protein. Functional activity of the elements was established in osseous and non-osseous cell lines and is in part related to the binding of osteoblast-specific complexes which enhance OC transcription. The contribution of several elements and binding of multiple classes of transcription factors to independent elements in both these domains serve to illustrate the complexity of control required for tissue-specific OC expression.
A gaze tracking method as an IPTV interface (2010)

In this paper, we propose a new wearable gaze tracking system based on the glasses-frame-based device which includes an eyecapturing camera. Gaze positions are calculated based on the geometric transform. Also, errors caused by facial movements are compensated by using the geometric relation of two corneal specular reflections. Menu selection is implemented based on the dwell time of gaze position. Experiments are performed in order to confirm the feasibility for applying the proposed method to internet protocol television (IPTV) with large scaled screen. Experimental results showed that the average rootmean-square (RMS) error of gaze detection under allowing facial movements was 1.38 degrees.
Narrow Stripe Membrane BH-DFB Lasers with Surface Corrugation for Stable Single-Mode Operation (2006)

A stable single-mode operation of membrane BH-DFB lasers was demonstrated under RT-CW operation by adopting a surface corrugation structure in order to maintain high index-coupling coefficient even for very narrow stripe width condition. It was estimated to be around 3000 cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-1</sup> for 0.6 mum stripe width from its stop-band width of 68 nm. A threshold pump power as low as 0.69 mW (lambda <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">pump</sub> = 980 nm) was achieved for the stripe width of 1.0 mum and the cavity length of 120 mum. By assuming an absorption coefficient of the pump beam of GaInAsP optical confinement layers and the active region to be 10000 cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-1</sup> , the corresponding threshold current was estimated to be 17 muA
EFFECT OF HIGH PRESSURE AND HIGH MAGNETIC FIELD ON MAGNETISM OF MnAs1-xSbx (0 ≤ x ≤ 0.3) (1988)

Magnetic and crystallographic properties, pressure effect of the Curie temperature region are measured for MnAs1-xSbx. Bean and Rodbell's theory with temperature dependent parameters can be applicable to the data some change of the electronic state occurs at x ≤ 0.4 in MnAs1-xSbx.
Vertical Underwater VLC Links over Cascaded Gamma-Gamma Turbulence Channels with Pointing Errors (2019)

Underwater visible light communication (UVLC) is a high capacity wireless connectivity solution with low latency, particularly appealing for real-time underwater video and image transmission. While attenuation and geometrical losses determine the average light intensity, underwater optical turbulence introduces fluctuations on the average received intensity, also known as fading. Due to relative movements of source and/or detector in harsh underwater environment, pointing errors further cause additional fading. In this paper, we consider a vertical underwater link modeled as a multi-layer channel where the fading coefficients associated with each layer are modeled as independent but not identically distributed Gamma-Gamma random variables. We model the displacements along the horizontal and elevation axes as independent and identically distributed Gaussian variables. Under these assumptions, we derive a closed-form expression for bit error rate (BER) expression. Based on asymptotical BER analysis, we determine the diversity order as a function of system and channel parameters. We further present Monte-Carlo simulation results to confirm the derived expressions.
Tri-band Multi-Constellation GNSS Antenna (2020)

This paper demonstrates a Tri band Multi-Constellation GNSS (Global Navigation Satellite System) Antenna solution for automotive applications. A single GNSS receive antenna that can be used in all global markets and support Tri-band operation is highly desirable for automotive applications. GNSS includes GPS, GLONASS, Galileo, and Beidou satellite constellations Each of these constellations use different bandwidths and carrier frequencies, thus making it is a challenge to design a single antenna solution to support global application. In this paper, a single Tri band multi-constellation patch antenna is designed, and simulation results are utilized to show the antenna design's capabilities.
Prepregnancy Consumption of Fruits and Fruit Juices and the Risk of Gestational Diabetes Mellitus (2012)

These data suggest that prepregnancy higher consumption of whole fruits is not associated with an increased GDM risk. The association between fruit juices and GDM risk appears to be nonlinear.
Preparation and characterization of a proton‐exchange membrane by the radiation grafting of styrene onto polytetrafluoroethylene films (2005)

Abstract Radiation‐induced simultaneous grafting of styrene onto polytetrafluoroethylene (PTFE) films and the subsequent sulfonation in the chlorosulfonic acid/dichloroethane were investigated. The effects of the main radiation grafting conditions, such as the type of solvents, irradiation dose, dose rate, the styrene concentrations, etc. , on the degree of grafting (DOG) were studied. To elucidate the influence of both the grafting and sulfonation conditions on the properties of the PTFE‐ g ‐polystyrene‐sulfonic acid (PSSA) membranes, the sulfonation conditions, including the sulfonation temperature and the concentration of the ClSO 3 H with respect to the DOG, were systematically evaluated. The grafted and sulfonated membranes were characterized by FTIR–ATR spectra, ion‐exchange capacity (IEC), water uptake, thickness measurement, etc. The as‐prepared PTFE‐ g ‐PSSA membranes in this work showed a good combination of a high IEC (0.85–2.75 meq g −1 ), acceptable water uptake (8.86–56.9 wt %), low thickness, and volume expansion and/or contraction. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 99: 1415–1428, 2006
piPipes: a set of pipelines for piRNA and transposon analysis via small RNA-seq, RNA-seq, degradome- and CAGE-seq, ChIP-seq and genomic DNA sequencing (2014)

Supplementary data are available at Bioinformatics online.
Alterações biomecânicas da coluna vertebral durante a gravidez (2010)

Dissertação apresentada na Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa para obtenção do grau de Doutor no Ramo da Engenharia Biomédica,Especialidade Biomecânica
Copper: an antioxidant nutrient for cardiovascular health (1994)

Dietary copper often is low in the Western diet; low intakes may affect all stages of atherosclerosis adversely. Impaired oxidative defense in copper deficiency contributes to hypercholesterolemia, hypertension, and impaired prostaglandin metabolism. Free copper ion does not exist in vivo; some in-vitro experiments are conducted with millions-fold excesses.
Catalyst development and mechanism (2015)

Preface Development of Selective Ruthenium-Based Catalysts Development of Selective Mo- and W-Based Catalysts Alkane Metathesis Diastereocontrol in Olefin Metathesis CAAC Catalysts in Olefin Metathesis Enantioselective Olefin Metathesis Catalysts Supported Catalysts and Catalysts in Heterogeneous Media Computational Investigations of Olefin Metathesis Intermediates in Olefin Metathesis
A double-blind trial of methocarbamol versus placebo in painful muscle spasm (1975)

A double-blind trial of methocarbamol versus placebo was carried out in 59 matched pairs of patients suffering from painful muscle spasm. Methocarbamol (1500 mg. q.d.s.) was found to be effective in approximately 60% of patients compared with 30% of patients receiving placebo (p less than 0.01). Side-effects were of almost equal incidence in the two groups.
Abstract 188: Total And Frontal Lobe White Matter Hyperintensity Volume And Impaired Mobility Among Older Adults (2012)

Introduction: Gait speed is associated with multiple adverse outcomes of aging. White matter hyperintensities (WMH) on magnetic resonance imaging (MRI) have been associated with gait speed, though few studies have examined changes in gait speed over time, regional localization of WMH, or enrolled participants community-based studies and in ethnic/racial minorities. We examined the association between a decline in gait speed and total and regional WMH volumes in a community-based study of aging. Methods: Participants were enrolled in the Washington Heights Inwood Columbia Aging Project (WHICAP), a cohort of Medicare recipients residing in Northern Manhattan. At enrollment participants underwent a comprehensive medical evaluation, as well as neuropsychological testing and assessment of gait speed via a 4 meter walk test. An MRI sub-study was started in 2004, at which time participants underwent a second gait speed measurement (mean 4.7 [SD=0.5] years apart). Odds ratios (OR) and 95% confidence intervals (CI) were calculated to examine the associations of large (defined as one standard deviation above the age-expected mean) WMH volume and regional WMH volumes (as a continuous measure) with the primary outcome (transition from normal to abnormal gait speed, defined as &lt; 0.4 meters/second) using logistic regression. Analyses were adjusted for socio-demographic factors, clinical history of stroke, hypertension, diabetes, body mass index, the presence of mild cognitive impairment or dementia, the length of time between the two physical performance measures, and the initial gait speed measure. Results: A total of 758 participants in WHICAP underwent MRI and two measures of gait speed. At the time of MRI the mean age was 80.3 (SD=5.6) and 114 (14.4%) had a large WMH volume. Large WMH volume was associated with a transition to an abnormal gait speed between the two visits (adjusted OR 3.09, 95% CI=1.21-7.93). Total frontal WMH volume (adjusted OR 1.06, 95%CI=0.93-1.20), or other regional volumes, were not associated with a transition to an abnormal gait speed between the two gait speed measurements. Conclusion: Total, but not regional, WMH are associated with slowing of gait over time. Modification of the known risk factors associated withWMH presents a potential strategy for the prevention of gait speed decline.
Subtraction MR Images in a Multiple Sclerosis Multicenter Clinical Trial Setting (2008)

MR image subtraction enabled detection of higher numbers of active MS lesions with greater interobserver agreement and exhibited increased power to distinguish treatment arms, as compared with a conventional pair-wise comparison of nonregistered MR images.
Cloudflow – A Framework for MapReduce Pipeline Development in Biomedical Research (2015)

Abstract - The data-driven parallelization framework Hadoop MapReduce allows analysing large data sets in a scalable way. Since the development of MapReduce programs can be a time-intensive and challenging task, the application and usage of Hadoop in Biomedical Research is still limited. Here we present Cloudflow, a high-level framework to hide the implementation details of Hadoop and to provide a set of building blocks to create biomedical pipelines in a more intuitive way. We demonstrate the benefit of Cloudflow on three different genetic use cases. It will be shown how the framework can be combined with the Hadoop workflow system Cloudgene and the cloud orchestration platform CloudMan to provide Hadoop pipelines as a service to everyone. The framework is open source and free available at https://github.com/genepi/cloudflow.
Three-Dimensionally Ordered Macroporous ZrO2:Tb3+ Films: Synthesis, Characterization, and Photoluminescence Properties (2011)

Three-dimensionally ordered macroporous (3DOM) ZrO 2 :Tb 3+ films on glass were successfully prepared using a polystyrene (PS) colloidal crystal template in combination with a sol–gel method. Microstructure of as-prepared 3DOM ZrO 2 :Tb 3+ films were examined by field emission scanning electron microscopy (FE-SEM). The results indicated that the material featured closely packed three-dimensional ordering of pores structure with (111) plane parallel to the surface of glass substrate. In addition, photoluminescence (PL) spectra showed a dominating green emission corresponding to 5 D 4 – 7 F J ( J = 3, 4, 5, 6) transitions of Tb 3+ under UV light excitation. Due to the presence of oxygen vacancies the PL peak from ZrO 2 host matrix was also observed.
Supplementation of Eurycoma longifolia Jack Extract for 6 Weeks Does Not Affect Urinary Testosterone: Epitestosterone Ratio, Liver and Renal Functions in Male Recreational Athletes. (2014)

Supplementation of ElJ i.e. Physta(®) at a dosage of 400 mg/day for 6 weeks did not affect the urinary T:E ratio and hence will not breach any doping policies of the International Olympic Committee for administration of exogenous testosterone or its precursor. In addition, the supplementation of ElJ at this dosage and duration was safe as it did adversely affect the liver and renal functions.
A Tuned-Input Tuned-Output VCO in 0.18μm CMOS (2007)

A fully-integrated 2.3-2.7GHz differential voltage-controlled oscillator derived from the classical tuned-input tuned-output ( <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">TITO</i> ) topology in 0.18μm CMOS is presented. It uses an auxiliary resonant tank for additional noise suppression and achieves measured phase noise values of -110dBc/Hz and -130.5dBc/Hz at 100 kHz and 1 MHz frequency offsets, respectively. With a current consumption of 7.5mA from a 1.8V supply, it achieves a figure-of-merit of 187.2dBc/Hz.
Supplementary fig 5 from Select Antitumor Cytotoxic CD8<sup>+</sup> T Clonotypes Expand in Patients with Chronic Lymphocytic Leukemia Treated with Ibrutinib (2023)

&lt;p&gt;Histogram of PD-1 expression in total CD3+, total CD8+, and the most abundant CD8+ clonotype in each patient after expansion with beads or autologous CLL cells.&lt;/p&gt;
Analysis of horn antennas with impedance walls (1990)

An integral-equation moment-method technique has been developed for rigorous analysis of horn antennas. Using this technique, one can accurately analyze a horn antenna with perfectly conducting or impedance walls, and with or without an infinite ground plane. Horn antenna performance in the case of impedance walls was investigated by using a high-permeability X-band magnetic absorbing nitrile material. The impedance tapering on the walls is shown to have a significant effect on the horn antenna pattern.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Upgrade of the CMS Hadron Outer Calorimeter with SIPMs (2012)

The CMS Hadron Outer Calorimeter (HO) is undergoing an upgrade to replace the existing hybrid photodetectors (HPDs) with silicon photo-multipliers (SIPMs). The chosen device is the Hamamatsu 3 × 3 mm2 50 μm pitch MPPC. The system has been developed to be a “drop-in” replacement of the HPDs. A complete control system of bias voltage generation, leakage current monitoring, temperature monitoring, and temperature control using solid state Peltier coolers has been developed and tested. 108 channels of the system have been installed into CMS and operated for more than 2 years. The complete system of about 2200 channels is in production and will be installed in the next LHC long shut-down scheduled for 2013.
2-Methyl-5-ethoxythiazole and Related Compounds1 (1950)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT2-Methyl-5-ethoxythiazole and Related Compounds1D. S. Tarbell, H. P. Hirschler, and R. B. CarlinCite this: J. Am. Chem. Soc. 1950, 72, 7, 3138–3140Publication Date (Print):July 1, 1950Publication History Published online1 May 2002Published inissue 1 July 1950https://doi.org/10.1021/ja01163a092RIGHTS & PERMISSIONSArticle Views167Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (361 KB) Get e-Alerts Get e-Alerts
The user view of file management (1983)

The structures in which users store their files facilitate retrieval by enabling users to deduce a file's contents from its place in the organization. This study examined structures created by UNIX users to organize their files within a hierarchical directory scheme, and examined the relation between structure and command usage. Users' difficulties in managing the complexity of a hierarchical structure limited the amount of information about files that these structures contained. Tree complexity increased in a negatively accelerating function with the number of files. Users who grouped their files into few directories arranged in shallow trees could navigate through the tree easily, but they sacrificed information: directory names were less specific, and users made more command errors. More sophisticated users created deeper trees. They were able to manage more files but also made extensive use of navigation aids.
Estimation of Chemical Structure of Notopterol Metabolites. (1999)

Notopterol, 5[(2E)-5-hydroxy-3,7-dimethyl-2,6-octadienyloxy]psoralen showed an inhibitory effect on aminopyrine N-demethylase activity in liver microsomes. In addition, notopterol has been found to be metabolized by cytochrome P450, and two kinds of metabolites were formed from notopterol. Furthermore, specific cytochrome P450 3A4 inhibitors which were isolated from grapefruit juice had the same furocoumarin structure as notopterol. Two metabolites of notopterol were separated by HPLC, and the chemical structures of the hydroxylated metabolites were estimated by 1H-NMR spectra and liquid chromatography-mass spectrometry.
Reed-Muller Identification (2021)

Ahlswede and Dueck identification has the potential of exponentially reducing traffic or exponentially increasing rates in applications where a full decoding of the message is not necessary and, instead, a simple verification of the message of interest suffices. However, the proposed constructions can suffer from exponential increase in the computational load at the sender and receiver, rendering these advantages unusable. This has been shown in particular to be the case for a construction achieving identification capacity based on concatenated Reed-Solomon codes. Here, we consider the natural generalization of identification based on Reed-Muller codes and we show that, although without achieving identification capacity, they allow to achieve the exponentially large rates mentioned above without the computational penalty increasing too much the latency with respect to transmission.
Das angiographische Bild der arteriovenösen Fisteln (1977)

The angiographic appearances and the significance of various angiographic signs are discussed in relation to 12 arteriovenous fistulae demonstrated angiographically in 11 patients. Dilatation of the supplying artery is an indication of the size of the shunt and is particularly prominent in the presence of multiple, congenital microfistulae. The technique developed in our clinic for investigating suspected or known A-V fistulae is described. This technique simplifies the differential diagnosis between the Klippel-Trénaunay syndrome and the prognostically less favourable Weber syndrome.
Human body postures from trinocular camera images (2002)

This paper proposes a new real-time method for estimating human postures in 3D from trinocular images. In this method, an upper body orientation detection and a heuristic contour analysis are performed on the human silhouettes extracted from the trinocular images so that representative points such as the top of the head can be located. The major joint positions are estimated based on a genetic algorithm-based learning procedure. 3D coordinates of the representative points and joints are then obtained from the two views by evaluating the appropriateness of the three views. The proposed method implemented on a personal computer runs in real-time. Experimental results show high estimation accuracies and the effectiveness of the view selection process.
Packet Information Block and System Packet Operations (2011)

Unlike C, packetC is based upon the presumption of underlying capabilities being provided by the operating system or generated by the compiler for a target platform. These include the management of packet handling functionality including receipt, buffering, and transmission as well as an initial level of decoding and manipulation on transmission. In addition, parallel processing management and a base set of control plane functionality must be present for packetC applications to interact with. These functions may differ from one system to another; however, a base set of functionality must remain consistent. To provide a common interface, the language specification for packetC mandates a predefined base set of types that are passed as parameters to main() as well as a set of built-in methods and operators.
Safety of Zilver PTX Drug-Eluting Stent Implantation Following Drug-Coated Balloon Dilation in a Healthy Swine Model (2017)

This preclinical study suggests that Zilver PTX stent implantation is a safe strategy after DCB angioplasty and might be considered for patients who require stenting after DCB treatment.