gebhart/patrepeval huggingface dataset:
Optically detected vibrations of crystal pendulum due to solar radiation (2020)

The optical experiments with suspended quartz crystals reflecting Laser-Doppler-Vibrometer (LDV) beam reveal an effect of crystal pendulum vibrations initiated by Sun’s radiation of heavy particles. The LDV measures speed S(t) of oscillating crystal surface. The Fourier-transform of S(t) returns a spectrum of the acoustic vibrations with a few hertz frequency. The S(t) is a sine-type curve with amplitude depending on the time and space orientation of crystal axes. Maximum vibrational speed and corresponding crystal displacement from a position of equilibrium are observed when quartz piezoelectric axis is aimed toward the Sun. Experimental evidences exclude involvement of any electro-magnetic wave. The theoretical calculations for an oscillator driven by a periodic pulse-force are compared to the experimentally detected oscillations. The computations give a work done by an external force to move the crystal from its equilibrium to maximum displacement. It yields a mass of a thinkable particle that is necessary to initiate and support observed vibrations. In the case of individual particles propagating with a solar wind speed and hitting crystal, particle mass is of the order of 10E-21 kg. The physics of crystal-particle interaction may be related to gravitational pull of quartz atoms/ions and particle quantum properties such as matter waves.
Tetrahedral projection using vertex shaders (2002)

Projective methods for volume rendering currently represent the best approach for interactive visualization of unstructured data sets. We present a technique for tetrahedral projection using the programmable vertex shaders on current generation commodity graphics cards. The technique is based on Shirley and Tuchman's Projected Tetrahedra (PT) algorithm and allows tetrahedral elements to be volume scan converted within the graphics processing unit. Our technique requires no pre-processing of the data and no additional data structures. Our initial implementation allows interactive viewing of large unstructured datasets on a desktop personal computer.
CDC42 guanosine triphosphatase mediates fibroblast migration after wounding (2000)

College of Physicians and Surgeons, Columbia University, 300 Winston Drive, Suite 2707, Cliffside Park, NJ, 07010, USA 201-886-7363
Evaluating the Potential of Multi-Color Heterodyne Absorption Spectroscopy in Turbulent Combustion (2006)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text J. W. Walewski, T. Krätschmer, and S. T. Sanders, "Evaluating the potential of multi-color heterodyne absorption spectroscopy in turbulent combustion," in Laser Applilcations to Chemical, Security and Environmental Analysis, Technical Digest (Optica Publishing Group, 2006), paper TuE10. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
ChemInform Abstract: SYNTHESIS OF O-METHYL-L-SERINE AND N(ALPHA)-TERT-BUTYLOXYCARBONYL-O-METHYL-L-SERINE (1974)

Aus dem Phthalimid (I) erhält man durch Kondensation mit Serin (II) die Carbonsäure (III), die mit p-Nitrobenzylchlorid zum Ester (IV) umgesetzt wird.
Phosphoinositide-Dependent Kinase 1 and p21-Activated Protein Kinase Mediate Reactive Oxygen Species–Dependent Regulation of Platelet-Derived Growth Factor–Induced Smooth Muscle Cell Migration (2004)

Smooth muscle cell migration in response to platelet-derived growth factor (PDGF) is a key event in several vascular pathologies, including atherosclerosis and restenosis. PDGF increases intracellular levels of reactive oxygen species (ROS) in vascular smooth muscle cells (VSMCs), but the ROS sensitivity of migration and of the signaling pathways leading to migration are largely unknown. In VSMCs, PDGF dose-dependently increased migration compared with nonstimulated cells, with a maximum increase at 10 ng/mL. Pretreatment with the antioxidant N-acetyl-cysteine, the flavin-containing enzyme inhibitor diphenylene iodonium, or the glutathione peroxidase mimetic ebselen significantly attenuated migration (PDGF alone, 5.0+/-1.1-fold; NAC, 1.8+/-0.2-fold; diphenylene iodonium, 1.4+/-0.3-fold migration; and ebselen, 2.0+/-0.5-fold migration), as did overexpression of catalase. Pretreatment of VSMCs with the Src inhibitor PP1 or dominant-negative Rac adenovirus significantly inhibited migration, but only Src activation was attenuated by ROS inhibitors. Phosphorylation of the Src- and Rac-effector p21-activated protein kinase (PAK) 1 on Thr423 (the phosphoinositide-dependent kinase-1 [PDK1] site) was attenuated by ROS inhibition, and infection of VSMCs with dominant-negative PAK1 adenovirus attenuated migration. Moreover, kinase-inactive K111N-PDK1 inhibited PAK1 phosphorylation on Thr423, and both K111N-PDK1 and Y9F-PDK1 significantly inhibited VSMC migration. PDK1 tyrosine phosphorylation was also ROS dependent. These data indicate that PDGF-induced VSMC migration is ROS dependent and identify the Src/PDK1/PAK1 signaling pathway as an important ROS-sensitive mediator of migration. Such information is critical to understanding the role of ROS in vascular diseases in which migration of VSMCs is an important component.
Protective Effect of Tea Catechins on the DNA Scission Induced in Tritiated Water (2002)

The protecting effect of (−)-epicatechin (EC), (−)-epicatechin gallate (ECg), (−)-epigallocatechin (EGC), (−)-epigallocatechin gallate (EGCg) and 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) on the DNA strand scission induced in tritiated water was analyzed. The scission with the hydroxyl radical produced by the decomposition of water molecules was decreased by the addition of above reagents. Protective effect of EGCg, EC and DMPO was dependent on their concentrations, but that of ECg and EGC was independent. Therefore, it was considered that certain amounts of ECg, EGC molecules might locate around DNA molecules, interacting with DNA.
Hierarchical mesoporous NiFe2O4 nanocone forest directly growing on carbon textile for high performance flexible supercapacitors (2016)

The spinel phase hierarchical mesoporous NiFe<sub>2</sub>O<sub>4</sub> nanocone forest growing on flexible CT can offer a large number of electrochemically active sites for redox reactions. This architecture provides an ultra large exposed surface for redox reactions, short lengths for electron transfer and clear channels for electrolyte diffusion.
Guardian: an experimental system for intelligent ICU monitoring. (1994)

We are developing an intelligent agent for patient monitoring named Guardian. It is applied to the post-operative monitoring and therapy management of cardiac surgery patients. Even though Guardian is an experimental system so far, we anticipate that in the short term it will be integrated with existing ICU information systems and critically evaluated on simulated patient cases. In evaluating the system, we aim to demonstrate that human-machine cooperation in information overload situations can improve the work environment of clinicians, improve health care delivery, and ultimately reduce health-care costs.
Anti-Tubercular Activity of Substituted 7-Methyl and 7-Formylindolizines and In Silico Study for Prospective Molecular Target Identification (2019)

Novel series of diversely substituted indolizines were designed, synthesized, and evaluated for their in vitro anti-mycobacterial activity against H37Rv and multi-drug-resistant (MDR) strains of <i>Mycobacterium tuberculosis</i> (MTB). Many compounds exhibited significant inhibitory activity against MTB H37Rv strains. Indolizines 2d, 2e, and 4 were also found to be active against MTB clinical isolates with multi-resistance to rifampicin and isoniazid. Indolizine <b>4</b> was identified as the most promising anti-mycobacterial agent, displaying minimum inhibitory concentration (MIC) values of 4 and 32 μg/mL against H37Rv and MDR strains, respectively. Furthermore, an in silico study was carried out for prospective molecular target identification and revealed favorable interactions with the target enzymes CYP 121, malate synthase, and DNA GyrB ATPase. None of the potent molecules presented toxicity against peripheral blood mononuclear (PBM) cell lines, demonstrating their potentiality to be used for drug-sensitive and drug-resistant tuberculosis therapy.
Reduction of measured toughness due to out‐of‐plane constraint in ductile fracture of aluminium alloy specimens (2010)

ABSTRACT It is generally believed that a lower bound on the fracture toughness of a material is obtained from a standard test, particularly in metals where yielding occurs prior to fracture. The understanding is that in such a test the material around the crack tip is highly constrained hence reducing the extent of yielding. In this paper, we report the results of fracture tests where a tensile load is applied to a biaxial aluminium alloy specimen in the direction parallel to the crack front in addition to the fracturing load normal to the crack surface. We show that in this case a lower fracture toughness is measured than that obtained from a standard test. Indeed, for the highest value of tensile load used in our tests the J ‐integral at fracture was half the value measured in a standard test. It is also shown that the volume of the plastic region can be used to measure the effect of constraint, irrespective of the manner in which the constraint arises. This approach suggests an even lower fracture toughness may be obtained than that measured here in certain loading conditions.
HOW BACTERIAL TOXINS PENETRATE THE INTESTINAL EPITHELIAL BARRIER: STRATEGIES TAKEN BY CHOLERA TOXIN AND BOTULINUM PROGENITOR TOXIN (2006)

A number of protein toxins produced by bacteria interact with the intestinal epithelium of the mammalian host as an essential step for their invasion into the host and for the exertion their pathogenicity. Therefore, elucidation of this step provides us with important information for understanding their pathogenicity. The molecular structures of two bacterial toxins, cholera toxin and botulinum progenitor toxin, and interactions of them with intestinal epithelial cells are focused on in this review. Cholera toxin produced by Vibrio cholerae is composed of a B moiety that binds to a cell-surface receptor and an A moiety that has toxic activity. This toxin is a well-characterized ADP-ribosyltransferase toxin, and the covalent modification of heterotrimeric Gs protein in the cytosol leads to the activation of adenylyl cyclase and a sequence of events culminating in a massive diarrheal disease. The transport pathway followed by this toxin from the plasma membrane to the cytosol was recently revealed. Botulinum neurotoxin causes foodborne botulism only when it is absorbed from the digestive tract and reaches the target neurons. Clostridium botulinum produces the neurotoxin always in the complex form (progenitor toxin), associated with other nontoxic proteins. A part of the nontoxic component was recently found to facilitate binding and internalization of the toxin into the intestinal epithelial cells. Therefore, the nontoxic component possibly has a role in the trans-epithelial transport of the toxin across the intestinal barrier. This review highlights these new insights on the interaction engaged by cholera toxin and botulinum progenitor toxin with intestinal epithelial cells.
Relationship Between Adherence to Remote Monitoring and Patient Characteristics: Observational Study in Women With Pregnancy-Induced Hypertension (2019)

ClinicalTrials.gov NCT03509272; https://clinicaltrials.gov/ct2/show/NCT03509272.
Characterizing Interfacial Bonds in Hybrid Metal AM Structures (2018)

The capabilities of various metal Additive Manufacturing (AM) processes, such as Powder Bed Fusion - Laser (PBF-L) are increasing such that it is becoming ever more common to use them in industrial applications. The ability to print atop a substrate broadens that scope of applications. There is ongoing research regarding the mechanical properties of additively processed materials, but not much regarding the interaction between additive material and its substrate. An understanding of the mechanical and performance properties of the AM/substrate interface is imperative. This paper describes a study of the strength properties of AM/substrate interfaces, with respect to torsion and tension, and compares them to their fully wrought and fully additive counterparts.
Wie Barrieren im Wissenstransfer überwunden werden können – Ergebnisse einer Studie zur Grundhaltung des Misstrauens oder Vertrauens (2015)

„Wissensmanagement ist eine Herausforderung für alle Unternehmen, welche in der Wissensgesellschaft überleben und ihre Wettbewerbsposition ausbauen wollen“ ([Pro12] 1). Vor diesem Hintergrund scheint insbesondere der Austausch und Transfer von Wissen ein hohes Wettbewerbspotenzial aufzuweisen und gestaltungsbezogen eine hohe Relevanz zu haben (vgl. [Leh14] 5 f., 13 ff.; [Krc95] 24 ff.), während klassische Kostensenkungsmaßnahmen weitgehend ausgereizt scheinen (vgl. [Nor11] 1 f.). Die Weitergabe von wertgenerierendem Wissen in Unternehmen ist jedoch mit Barrieren verbunden, die stark auf Egoismen und Hemmnissen beruhen, und die es zu überwinden gilt. Der nachfolgende Beitrag zeigt reinterpretiert die wichtigsten Ergebnisse einer im Rahmen einer Dissertation erfolgten empirischen Untersuchung zur Überwindung von Barrieren im Wissenstransfer auf und leitet daraus Handlungsempfehlungen für die Praxis ab [Sch13].
Cr4+:Gd3Sc2Ga3O12 passive Q-switch for the Cr3+:LiCaAlF6 laser (1994)

A Cr4+:Gd3Sc2Ga3O12 (Cr4+:GSGG) broad-band saturable absorber has been demonstrated to be an excellent passive Q-switch for the flashlamp-pumped tunable Cr3+:LiCaAlF6 (Cr:LiCAF) laser at room temperature. A single Q-switched laser output pulse of 11 mJ in energy and 37 ns in duration at 778 nm was obtained in a nonoptimized laser.
Solar Cell Receiver Free-Space Optical for 5G Backhaul (2019)

We introduce new optical wireless backhaul technology using solar cells as data receivers. We argue that this new technology can be reliable and low-cost. We introduce a real-world pilot use case within the UK 5G project ‘RuralFirst’.
Understanding the Self‐Healing Mechanism of Polyurethane Elastomer Based on Hydrogen Bonding Interactions through Molecular Dynamics Simulation (2021)

Abstract The healing behavior of polyurethane (PU) elastomer is studied based on microcrack models by molecular dynamics simulation. It is found that PU elastomer has a self‐healing capacity at 25, 50, and 70 °C when the molar ratio of polypropylene carbonate polyol (PPC), hexamethylene diisocyanate (HDI), and 1,6‐hexamethylenediamine is 1:2:1. While the molar ratio of PPC, HDI, and 1,6‐hexamethylenediamine is 1:1.33:0.33 or 2:3:1, the PU is never healed at 25, 50, and 70 °C. With the temperature rising, the self‐healing rate is the fastest when the temperature is at 70 °C. Besides, the self‐healing mechanism of PU elastomer is analyzed. It is found that the hydrogen bonds of Type 6 which are produced by urea groups and ester groups, Type 1 which are produced by urea groups and urea groups, and Type 2 which are produced by urea groups and urethane groups have made a great effect on self‐healing behavior. Dynamic exchange is visually observed between different hydrogen bonds. Meanwhile, the strength, type, number of different types, and existence time of hydrogen bonds are elaborated. This study deepens the understanding of the mechanism about healing based on hydrogen bonding interactions.
User-Priority-Based Power Control in D2D Networks for Mobile Health (2017)

A device-to-device (D2D) assisted cellular network is pervasive to support ubiquitous healthcare applications, since it is expected to bring the significant benefits of improving user throughput, extending the battery life of mobiles, etc. However, D2D and cellular communications in the same network may cause cross-tier interference (CTI) to each other. Also a critical issue of using D2D assisted cellular networks under a healthcare scenario is the electromagnetic interference (EMI) caused by RF transmission, and a high level of EMI may lead to a critical malfunction of medical equipments. In consideration of CTI and EMI, we study the problem of optimizing the energy efficiency (EE) across the mobile users in different priorities (different levels of emergency) within the Internet of vehicles for mobile health, and propose a penalty-function algorithm of power control to solve the aforementioned problem. Numerical results demonstrate that the proposed algorithm can achieve remarkable improvements in terms of EE, while ensuring an allowable level of EMI on medical equipments.
PENGARUH GAYA KEPEMIMPINAN DAN MOTIVASI KERJA TERHADAP KINERJA PEGAWAI (2011)

The objective of the research is to determine the effect of leadership style and work motivation on employee performance. The research was conducted at Dinas Pembinaan Mental TNI-AD in Jakarta, 2010 with n=66 selected randomly. The result of research are as follows: (1) there is significant direct effect of leadership style on employee performance at Dinas Pembinaan Mental TNI-AD in Jakarta; (2) there is significant direct effect of work motivation on empoyee performance at Dinas Pembinaan Mental TNI-AD in Jakarta; and (3) there is significant direct effect of leadership style on employeeâ€™s work motivation at Dinas Pembinaan Mental TNI-AD in Jakarta. Based on the result of research, the employee performace at Dinas Pembinaan Mental TNI-AD in Jakarta could be enhanced by increasing leadership style and work motivation as significant determinant factors.
Development of a High-Throughput Homogeneous AlphaLISA Drug Screening Assay for the Detection of SARS-CoV-2 Nucleocapsid (2020)

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is in urgent need of therapeutic options. High-throughput screening (HTS) offers an opportunity to rapidly identify such compounds. In this work, we have developed a homogeneous cell-based HTS system using AlphaLISA detection technology for the SARS-CoV-2 nucleocapsid protein (NP). Our assay measures both recombinant and endogenous NP from viral lysates and tissue culture supernatants (TCS) in a sandwich-based format using two monoclonal antibodies against the NP analyte. Viral NP was detected and quantified in both tissue culture supernatants and cell lysates, with large differences observed between 24 and 48 h of infection. We simulated viral infection by spiking recombinant NP into 384-well plates with live Vero-E6 cells and were able to detect the NP with high sensitivity and a large dynamic range. Antiviral agents that inhibit either viral cell entry or replication decrease the AlphaLISA NP signal. Thus, this assay can be used for high-throughput screening of small molecules and biologics in the fight against the COVID-19 pandemic.
Two-step cleavage of hairpin RNA with 5' overhangs by human DICER (2011)

The two-step cleavage of a hairpin RNA with 5' overhangs shows that DICER releases double-stranded RNAs after the first cleavage and binds them again in the inverse direction for a second cleavage. These findings have implications for how DICER may be able to interact with or process differing precursor structures.
Dynamic spectrum access with prioritization in open spectrum wireless networks (2008)

Dynamic spectrum access (DSA) is important for spectrum management in the future. DSA with prioritization for two types of radio systems are presented through analytical formulation. The DSA with prioritization model is solved numerically using a two-dimensional Markov chain. Grades of service (GoSs) like system airtime and blocking probabilities are considered. The performance of these GoS measures and the effect of the size of the number of frequency channels for DSA with prioritization are evaluated. Numerical results illustrate that the advantages of DSA with prioritization for one type radio system over another type of radio system.
Hydrothermal Liquefaction of Softwood: Selective Chemical Production Under Oxidative Conditions (2016)

This work was conducted to determine the effect of oxygen on hydrothermal liquefaction of softwood for the production of valuable chemicals. Softwood was subjected to liquefaction in the presence and absence of either 1.6 g/L sodium carbonate or 5 bar oxygen gas. The oxygen supplementation diverted sugars from dehydration toward oxidation resulting in 4-fold elevated yields of organic acids. Dissolved sugars and furans showed maxima in narrow temperature regions of 170–190 and 210–230 °C while the yields (weight percentage based on dry wood) of organic acids, phenolic substances, and bio-oil reached their respective maxima of 10.4%, 3.5%, and 7.4% at 230–270 °C. These results of oxidative hydrothermal liquefaction advance sustainable production of chemicals from renewable lignocellulose.
Emotion Enhancement for Facial Images Using GAN (2020)

Labeled images play an important role for training convolutional neural networks (CNN). In particular, training CNNs for facial emotion classification, the publicly available datasets suffer from noisy labels and inter-class imbalance problem. In this paper, we adopt a Generative Adversarial Network (GAN) to alleviate both noisy labeling and inter-class imbalance problems. Specifically, the noisy labelled images are identified by cross-checking the classified results with two fine-tuned CNNs and their facial emotions are strengthened by a GAN. Also, some of the neutral emotion images are transformed into minor emotion classes to solve the imbalance problem.
Biochemical markers of premature birth (2005)

Summary: In this article the results of the research of diagnostic importance of myoglobin determination in peripheral blood and amniotic fluid, fetal fibronectin examination in cervicovaginal composition contents of a pregnant woman are represented in prediction of premature birth.
Digital holographic microscopy applied to neurociences (2012)

Quantitative phase imaging techniques including digital holographic microscopy (DHM) have emerged recently in life sciences and can be aimed at monitoring and quantifying, in a non-invasive way, cellular processes. Due to its interferometric nature, the DHM phase signal or optical path difference (OPD), which depends on both cell thickness and integral RI can be measured with a high sensitivity. Here, we present an application of digital holographic microscopy (DHM) dedicated towards early and label free detection of neuronal death. Practically, through the quantitative measurements of OPD, the early neuronal cell volume regulation, following glutamate-mediated excitotoxicity, has been accurately monitored. Finally, the efficiency of this early cell volume regulation process has been successfully correlated with the occurring of the subsequent neuronal death assessed with the widely accepted trypan blue viability method.