gebhart/patrepeval huggingface dataset:
End-to-end QoS provisioning across heterogeneous domains (2002)

Heterogeneity with respect to networking technology is increasing, for example, considering QoS support. Different QoS have been developed for the Internet and for ATM networks. In the context of the Internet, integrated services (IntServ) as well as differentiated services (DiffServ) are considered. As a result, networking scenarios with different QoS models being applied in different domains are very probable. Within this paper an Inter Domain QoS router is introduced and its functionality is outlined with respect to RSVP based domains and to ATM domains. Reduced signaling of RSVP, connection establishment and connection re-negotiation is supported within the ATM domain in order to follow the dynamic QoS changes of RSVP. A local testbed has been established and simulation experiments have been conducted in order to evaluate the performance of the Inter Domain QoS router.
Liver-specific disruption of PPARγ in leptin-deficient mice improves fatty liver but aggravates diabetic phenotypes (2003)

To elucidate the function of PPARgamma in leptin-deficient mouse (ob/ob) liver, a PPARgamma liver-null mouse on an ob/ob background, ob/ob-PPARgamma(fl/fl)AlbCre(+), was produced using a floxed PPARgamma allele, PPARgamma(fl/fl), and Cre recombinase under control of the albumin promoter (AlbCre). The liver of ob/ob-PPARgamma(fl/fl)AlbCre(+) mice had a deletion of exon 2 and a corresponding loss of full-length PPARgamma mRNA and protein. The PPARgamma-deficient liver in ob/ob mice was smaller and had a dramatically decreased triglyceride (TG) content compared with equivalent mice lacking the AlbCre transgene (ob/ob-PPARgamma(fl/fl)AlbCre(-)). Messenger RNA levels of the hepatic lipogenic genes, fatty acid synthase, acetyl-CoA carboxylase, and stearoyl-CoA desaturase-1, were reduced in ob/ob-PPARgamma(fl/fl)AlbCre(+) mice, and the levels of serum TG and FFA in ob/ob-PPARgamma(fl/fl)AlbCre(+) mice were significantly higher than in the control ob/ob-PPARgamma(fl/fl)AlbCre(-) mice. Rosiglitazone treatment exacerbated the fatty liver in ob/ob-PPARgamma(fl/fl)AlbCre(-) mice compared with livers from nonobese Cre(-) mice; there was no effect of rosiglitazone in ob/ob-PPARgamma(fl/fl)AlbCre(+) mice. The deficiency of hepatic PPARgamma further aggravated the severity of diabetes in ob/ob mice due to decreased insulin sensitivity in muscle and fat. These data indicate that hepatic PPARgamma plays a critical role in the regulation of TG content and in the homeostasis of blood glucose and insulin resistance in steatotic diabetic mice.
Enhanced photoresponse of Cu2O/ZnO heterojunction with piezo-modulated interface engineering (2014)

The ability to arbitrarily regulate semiconductor interfaces provides the most effective way to modulate the performance of optoelectronic devices. However, less work has been reported on piezo-modulated interface engineering in all-oxide systems. In this paper, an enhanced photoresponse of an all-oxide Cu2O/ZnO heterojunction was obtained by taking advantage of the piezotronic effect. The illumination density-dependent piezoelectric modulation ability was also comprehensively investigated. An 18.6% enhancement of photoresponse was achieved when applying a −0.88% compressive strain. Comparative experiments confirmed that this enhancement could be interpreted in terms of the band modification induced by interfacial piezoelectric polarization. The positive piezopotential generated at the ZnO side produces an increase in space charge region in Cu2O, thus providing an extra driving force to separate the excitons more efficiently under illumination. Our research provides a promising method to boost the performance of optoelectronics without altering the interface structure and could be extended to other metal oxide devices.
Cloning and in vivo and in vitro regulation of cyclic AMP-dependent carbon starvation genes from Escherichia coli (1990)

The regulation of three Escherichia coli carbon starvation (cst) genes fused to lacZ was examined. Expression of these genes is induced by starvation for a carbon source. The role of carbon and cyclic AMP (cAMP) availability and of an altered-function crp mutation were investigated for their effect on cst expression in vivo. The experiments indicated that cAMP concentrations controlled the absolute expression of one cst fusion, but the other two cst fusions were dependent upon some component not present in exponentially growing cells under conditions of glucose excess, even when cAMP was added. To examine the regulation of these genes in further detail, the three cst::lacZ fusions were cloned on multicopy plasmids. All three cst::lacZ fusions retained their inducible regulatory phenotype in the multicopy state. Analysis of the expression of the cloned cst::lacZ fusions in an in vitro-coupled transcription-translation cell-free system demonstrated that the predominant promoter(s) present on each cloned DNA was dependent on sigma 70 for expression. In vitro cAMP titration curves indicated that this molecule was necessary and sufficient for the expression of one fusion but not sufficient for the second fusion, while the third fusion exhibited constitutive levels of expression in vitro. The results are discussed in the context of the E. coli carbon starvation response.
Solution Structure and Dynamics of Myeloid Progenitor Inhibitory Factor-1 (MPIF-1), A Novel Monomeric CC Chemokine (2001)

MPIF-1, a CC chemokine, is a specific inhibitor of myeloid progenitor cells and is the most potent activator of monocytes. The solution structure of myeloid progenitor inhibitor factor-1 (MPIF-1) has been determined by NMR spectroscopy. The structure reveals that MPIF-1 is a monomer with a well defined core except for termini residues and adopts the chemokine fold of three beta-strands and an overlying alpha-helix. In addition to the four cysteines that characterize most chemokines, MPIF-1 has two additional cysteines that form a disulfide bond. The backbone dynamics indicate that the disulfide bonds and the adjacent residues that include the functionally important N-terminal and N-terminal loop residues show significant dynamics. MPIF-1 is a highly basic protein (pI >9), and the structure reveals distinct positively charged pockets that could be correlated to proteoglycan binding. MPIF-1 is processed from a longer proprotein at the N terminus and the latter is also functional though with reduced potency, and both proteins exist as monomers under a variety of solution conditions. MPIF-1 is therefore unique because longer proproteins of all other chemokines oligomerize in solution. The MPIF-1 structure should serve as a template for future functional studies that could lead to therapeutics for preventing chemotherapy-associated myelotoxicity.
Introduction to Probability and Statistics: Principles and Applications for Engineering and the Computing Sciences (1990)

From the Publisher:
This well-respected text is designed for the first course in probability and statistics taken by students majoring in Engineering and the Computing Sciences. The prerequisite is one year of calculus. The text offers a balanced presentation of applications and theory. The authors take care to develop the theoretical foundations for the statistical methods presented at a level that is accessible to students with only a calculus background. They explore the practical implications of the formal results to problem-solving so students gain an understanding of the logic behind the techniques as well as practice in using them. The examples, exercises, and applications were chosen specifically for students in engineering and computer science and include opportunities for real data analysis.
2-Arylnaphthoquinone analogues: potential anti-TB and pro-apoptotic agents (2011)

A useful library of substituted 2-arylnaphthoquinones prepared by reaction between the corresponding bromonaphthoquinones and arylboronic acids via Suzuki-Miyaura protocols has been established. Conversion of some of the products into new analogues was effected.
Phase I Trial of Zoledronic Acid + Imatinib Mesylate (Gleevec) in Patients With Bone Metastases (2010)

The combination of zoledronic acid + Gleevec is not recommended in patients with bone metastases because of toxicity and limited clinical efficacy.
Fabrication of highly ordered nanoporous Si with high aspect ratio through prepatterning of Si using porous alumina mask (2014)

Highly ordered nanoporous Si was prepared through the prepatterning of Si using an anodic porous alumina mask. A highly ordered array of shallow nanoconcaves was formed on Si(100) by dry etching through the nanopores of the anodic porous alumina. During electrochemical etching of the prepatterned Si, nanopores were generated at the shallow concaves. Consequently, highly ordered arrays of deep nanopores with intervals of 200 and 100 nm were obtained. This result demonstrated that the shallow concave features on Si act as initiation sites for the development of nanopores. This process is useful for the preparation of highly ordered porous Si of nanometer scale.
Effects of FK506 on nerve regeneration and reinnervation after graft or tube repair of long nerve gaps (2001)

Abstract We compared the effects of FK506 administration on regeneration and reinnervation after sciatic nerve resection and repair with an autologous graft or with a silicone tube leaving a 6‐mm gap in the mouse. Functional reinnervation was assessed by noninvasive methods to determine recovery of motor, sensory, and sweating functions in the hindpaw over 4 months after operation. Morphometric analysis of the regenerated nerves was performed at the end of follow‐up. The nerve graft allowed for faster and higher levels of reinnervation in the four functions tested than silicone tube repair. Treatment with FK506 (for the first 9 weeks only) resulted in a slight, although not significant, improvement of the onset of reinnervation and of the maximal degree of recovery achieved after autografting. The recovery of pain sensibility and of the compound nerve action potentials in the digital nerves, which directly depend on axonal regeneration, showed better progression with FK506 than reinnervation of muscles and sweat glands, which require reestablishment of synaptic contacts with target cells. The myelinated fibers in the regenerated nerve showed a more mature appearance in the FK506‐treated rats. However, FK506 showed a marginal effect in situations in which regeneration was limited, as in a silicone tube bridging a 6‐mm gap in the mouse sciatic nerve. In conclusion, treatment with FK506 improved the rate of functional recovery after nerve resection and autograft repair. © 2001 John Wiley &amp; Sons, Inc. Muscle Nerve 24: 905–915, 2001
O-GlcNAc Peptide Epoxyketones Are Recognized by Mammalian Proteasomes (2009)

Cytosolic and nuclear proteins may be subject to both O-GlcNAcylation and proteasomal degradation. By means of activity-based profiling, we demonstrate that O-GlcNAc serine-containing peptide epoxyketones bind to the proteasome catalytic active sites and thus provide the first clear evidence that proteasomes recognize peptides post-translationally modified with a GlcNAc moiety.
Coherent Detection with an Asynchronous Geiger Mode Array (2015)

Large format arrays of coherent detectors enable several advanced EO sensing modes including aperture synthesis, turbulence compensation and velocity sensing. Coherent detector arrays that operate in a linear mode are desirable; however, they are often impractical because read-out’ss offering sufficient pixel density and A/D rates are not available. Photon-counting coherent detector arrays based on Geiger-mode Avalanche Photo-Diode (GmAPD) arrays are attractive because they offer large array format, and the output is digitized via the photon arrival times. Furthermore, asynchronous GmAPD arrays offer improved blocking efficiency which in turn improves the frequency fidelity. In fact, the response time of an asynchronous GmAPD macropixel exceeds the reset time of the individual detectors. In this paper we present the results of analysis, modeling and experiments that show the performance levels attainable with asynchronous GmAPD arrays.
Solubility of Oxygen in Organic Solvents and Calculation of the Hansen Solubility Parameters of Oxygen (2014)

The solubility of oxygen in 21 pure organic solvents was measured at 298.2 K and 101.33 kPa using the static method. The Hansen solubility parameters (HSPs) of oxygen were determined from the measured solubilities in the pure solvents. The HSPs of oxygen were δd = 6.7 MPa1/2, δp = 0.0 MPa1/2, and δh = 3.8 MPa1/2, where d, p, and h stand for dispersion forces, dipole interaction, and hydrogen bonding, respectively. A linear relationship between the log of the gas solubility (log xG) in pure solvents and the difference between the HSP values of oxygen and the pure solvents was obtained with a high correlation coefficient of 0.944. In addition, the solubilities of oxygen in mixed solvents were measured, and these were compared with the oxygen gas solubility calculated from the HSPs of oxygen.
Electromagnetic interference shielding of graphite/acrylonitrile butadiene styrene composites (2010)

Abstract Dispersion of graphite within the acrylonitrile butadiene styrene matrix demonstrates enhanced electromagnetic interference shielding of composites through the use of tumble mixing technique. A shielding effectiveness of 60 dB with 15 wt % of graphite has been achieved. D shore hardness data revealed a little decrease in hardness of composites with rise in graphite content. DC conductivity measurements revealed a fairly low percolation threshold at 3 wt % of graphite. The conductivity exhibited by 15 wt % composite is 1.66 × 10 −1 S/cm. These composites are fit for use as an effective and convenient EMI shielding material because of easy processing, better hardness, light weight, and, reasonable shielding efficiency. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2011
Syntheses of R-β-rutinosides by rutin-degrading reaction (2009)

Rutinose and five R-beta-rutinosides were obtained by means of rutin-degrading reaction in water or aqueous alcohol (ROH, R = methyl, ethyl, propyl, isopropyl, and benzyl) with rutin-degrading enzyme as catalyst and rutin as starting material in 84-94% yields, of which methyl-beta-rutinoside, propyl-beta-rutinoside, isopropyl-beta-rutinoside, and benzyl-beta-rutinoside are firstly reported in this paper. Based on spectral analysis, the structures of all products were elucidated.
Extension of analytic results for aPT-symmetric structure (2016)

The PT-symmetric optical grating with index profile e2ibz has been shown to have the interesting property of being essentially invisible for light incident from one side, while possessing greatly enhanced reflection at a particular wavelength for light incident from the other side. We extend a previous analysis of this grating to obtain an analytic solution for the case when the grating is embedded on a substrate, with different refractive indices on either side. We also generalize the previous case of normal incidence to incidence at an arbitrary angle. In that case the enhanced reflection occurs at a particular angle of incidence for a given wavelength. Finally we discuss how the grating may be used to give lasing.
Instabilities in Conventional Multi-Coil MRI Reconstruction with Small Adversarial Perturbations (2021)

Although deep learning (DL) has recently received significant attention in accelerated MRI, recent studies suggest that small perturbations may lead to large instabilities in DL-based reconstructions. This has also highlighted concerns for their utility in clinical settings. However, these works focus on single-coil acquisitions, which are not practically relevant. In this work, we investigate how small adversarial perturbations affect multi-coil MRI reconstruction, particularly using conventional non-DL methods. Our results indicate that for multi-coil MRI reconstruction, conventional parallel imaging and multi-coil compressed sensing (CS) methods also exhibit considerable instabilities against small adversarial perturbations. Moreover, for physics-guided DL reconstructions that utilize the forward encoding operator explicitly, such small perturbations predominantly target the linear data-consistency units. These results suggest that at high acceleration rates, adversarial attacks exploit the ill-conditioning of the forward encoding operator.
The Art of Ballets Russes: The Serge Lifar Collection of Theater Designs, Costumes, and Paintings at the Wadsworth Atheneum, Hartford, Connecticut. By Alexander Schouvalofi. New Haven: Yale University Press, 1998. 352 pp. Appendixes. Notes. Bibliography. Index. Plates. Photographs. $65.00, hard bound. (1999)

The Art of Ballets Russes: The Serge Lifar Collection of Theater Designs, Costumes, and Paintings at the Wadsworth Atheneum, Hartford, Connecticut. By Alexander Schouvalofi. New Haven: Yale University Press, 1998. 352 pp. Appendixes. Notes. Bibliography. Index. Plates. Photographs. $65.00, hard bound. - Volume 58 Issue 3
The SSL landscape (2011)

The SSL and TLS infrastructure used in important protocols like HTTPs and IMAPs is built on an X.509 public-key infrastructure (PKI). X.509 certificates are thus used to authenticate services like online banking, shopping, e-mail, etc. However, it always has been felt that the certification processes of this PKI may lack in stringency, resulting in a deployment where many certificates do not meet the requirements of a secure PKI.
ChemInform Abstract: TOTAL SYNTHESIS OF ELFAMYCINS: AURODOX AND EFROTOMYCIN. 2. COUPLING OF KEY INTERMEDIATES AND COMPLETION OF THE SYNTHESIS (1985)

Abstract Die in der vorangegangenen Arbeit synthetisierten Bausteine (1), (II), (IV), (V) und (VII) werden zu den Titelverbindungen weiterverarbeitet.
Analysis of homotypic and heterotypic serum immune responses to rotavirus proteins following primary rotavirus infection by using the radioimmunoprecipitation technique (1993)

Three sequential serum samples collected from each of 20 young children with a naturally acquired primary rotavirus infection were assayed by the radioimmunoprecipitation technique for immunoglobulin G antibodies to rotavirus structural and nonstructural proteins of the four major human rotavirus serotypes G1, P1A; G2, P1B; G3, P2; and G4, P2. Fourteen children were infected with a serotype G1 rotavirus strain and six children were infected with a serotype G4 rotavirus strain. Sera were collected from each child in the acute and convalescent periods postinfection and also approximately 4 months later. Serum immune responses to rotavirus core antigens VP2 and VP3, to the major inner capsid antigen VP6, to nonstructural proteins NS35, NS28, and NS26, and to the outer capsid neutralization antigen VP4 of all test strains were detected in the majority of patients. These responses do not appear to be influenced by the G type or P type of the rotavirus strain used in the reactions. Homologous responses to the main neutralization antigen VP7 were detected in 93% of patients with serotype G1 infections and 50% of patients with serotype G4 infections. Heterologous VP7 responses were less frequently detected and were restricted to G1, G3, and G4 serotype rotavirus strains. No responses to VP7 of the serotype G2 rotavirus strain were detected in any patients. Heterotypic immune responses to the neutralization antigens, at least following serotype G1 and G4 infections, therefore appear to consist primarily of responses to VP4 rather than to VP7.
Behavioral synthesis of asynchronous systems: a methodology (2003)

In asynchronous system, initiation and completion of operations are events that can occur at any instant and the execution time is data dependent. Thus if an asynchronous timing model is considered, we can provide scheduling and resource allocation methods which will have a significant impact on the performance and the area of the final implementation. Until now the different methods proposed for high-level synthesis (HLS) do not apply to the above topics. This paper proposes a methodology for the scheduling of asynchronous systems. It is based on the average delay.
Multi-operand block-floating point arithmetic for image processing (2010)

We extend the application of block-floating point arrays to multi-operand algebraic expressions consisting of additions and multiplications. The proposed method enables automatic runtime calculation of binary shifts of array elements. The shifts are computed for all elementary operations in an expression using a dataflow graph. The method attempts to preserve accuracy across the entire expression while avoiding overflow. A variety of common computer vision and image processing operations can be efficiently realized in fixed-point processors using the proposed technique. It eliminates the need to hand-craft block-floating point implementations for each new operation or processor. The result is a reduction in development time and the likelihood of errors.
Rheumatoid factors from patients with rheumatoid arthritis react with beta 2-microglobulin. (1992)

IgM rheumatoid factors (RF) from 18 sera of rheumatoid arthritis (RA) patients isolated from monomeric IgG affinity columns showed strongly positive ELISA reactions with human beta 2-microglobulin (beta 2m), as well as with recombinant beta 2m. When the same RA sera were adsorbed to beta 2m-Sepharose affinity columns, eluted material showed predominant IgM anti-Fc of IgG and anti-beta 2m reactivity. Inhibition reactions with "RF" obtained from IgG affinity columns showed slightly higher reactivity of RF for Fc over beta 2m; however, when RF from the same RA serum had been adsorbed to and eluted from beta 2m affinity columns, beta 2m showed greater inhibition than Fc for RF reacting with either beta 2m or Fc on ELISA plates. Thus two overlapping populations of RF were identified in RA sera showing reactivity with both beta 2m and Fc of IgG. When RF were isolated from IgG columns, affinity was slightly higher for Fc than beta 2m. Conversely, RF eluted from beta 2m Sepharose reacted slightly more with beta 2 m than Fc. Trypsin digests of a polyclonal RA IgM RF showed no beta 2m reactivity in Fc mu 5 fragments. Fab mu RF retained slight anti-Fc IgG but no residual anti-beta 2m activity. Monoclonal human IgM, IgG, or IgA RF either from mixed cryoglobulins or EBV-stimulated RA lymphoid cell lines showed negative or occasional weakly positive anti-beta 2m activity. Overlapping 7-mer peptide ELISA analysis of the entire 99-amino acid sequence of beta 2m showed a major RF-reactive linear hydrophilic sequence at positions 56-60 which included a 3-amino acid exact homology to positions 401, 403, and 404 of the C gamma 3 domain. A peptide encompassing this sequence produced 90% inhibition of RF binding to whole beta 2m. Substitution of neutral glycines for each amino acid throughout the reactive epitope at positions 56-66 indicated that lysine at position 58 aspartic acid at 59, and tryptophane at 60 represented major portions of the RF-reactive epitope. These findings indicate that human RF derived from patients with RA react with other epitopes besides those present on IgG Fc, including epitopes on human beta 2m. For many years serum RF3 found in patients with RA have been regarded as premier examples of autoantibodies to autologous IgG.(ABSTRACT TRUNCATED AT 400 WORDS)