gebhart/patrepeval huggingface dataset:
Abstract 14195: Physiological Ventilation Volume Improves Return of Spontaneous Circulation in a Pig Model of Eight-minute Untreated Cardiac Arrest (2016)

Background: It is not known whether the duration of cardiac arrest affects the ventilatory requirements during CPR. Hypothesis: For prolonged cardiac arrest, current recommended ventilation pattern is nonideal for satisfactory results during CPR. Methods: In 32 pigs (intubated and ventilated with a tidal volume of 10 mL/kg and a frequency which maintained P ET CO 2 between 35 and 40 mmHg), ventricular fibrillation (VF) was induced and chest compressions (CC) were started after 4min or 8min. Sixteen pigs of 4min VF randomly received mechanical ventilation with a tidal volume of 7 mL/kg and a frequency of 10/min (Guideline-4, n=8) or the same tidal volume and frequency as baseline (Baseline-4, n=8). Sixteen pigs of 8min VF had similar groups (Guideline-8 and Baseline-8). Following 10min uninterrupted CC and mechanical ventilation, up to three defibrillations was administered. Measurements were taken at baseline, 5th and 10th minute of CC. Results: Ventilation in Baseline-4 (minute ventilation 5.7±1.0 L/min) resulted in higher PHa, PaO 2 , mean airway pressure, and lower PaCO 2 , SvO2, and P ET CO 2 than Guideline-4 (2.3±0.4 L/min) both at the 5th and 10th minute of CC ( p p 2 , PHv, mean airway pressure, and lower PaCO 2 and PvCO 2 than Guideline-8 (2.4±0.5 L/min) both at the 5th and 10th minute ( p Hemodynamic parameters were not statistically different between two groups of 8min VF ( p p =0.039). Conclusions: For 4min VF pig models, guideline-based ventilation was proper during CPR, however, physiological ventilation volume resulted in higher ROSC during CPR for 8min VF.
A MASH-Controlled Multilevel Power Converter for High-Efficiency RF Transmitters (2010)

Envelope tracking (ET) is one of the most promising transmitter architectures proposed to increase the efficiency of modern wireless communication system. An ET transmitter consists of a linear RF power amplifier and a high-efficiency envelope amplifier, which is always a switched-mode power converter. The envelope amplifier provides a varying drain (collector) bias voltage, which tracks the envelope of the RF input signal, for the RF power amplifier. Thus, the RF power amplifier keeps working in high-efficiency region of most of the time. Therefore, the overall efficiency of the transmitter is increased. This paper proposes a multistage noise-shaping-technique-controlled multilevel power converter to perform as the envelope amplifier in an ET transmitter. Experimental results show that the proposed power converter can reproduce any envelope signals with the maximum spectrum component of 300 kHz and give maximum instantaneous power of 20 W. Compared with pulsewidth modulation, the noise-shaping technique can shape the ripple into noise and the noise will be attenuated by the low-pass filter, which results a better performance, while maintaining high efficiency as well.
Die Sulfonierung aromatischer Isocyanate: Sulfoniertes p‐Tolylisocyanat — eine Röntgen‐Strukturanalyse (1982)

Abstract Das vollständige Manuskript dieser Zuschrift erscheint in: Angew. Chem. Suppl. 1982 , 1875. DOI: 10.1002/ange.198218750
Laser ablation system, and method of decontaminating surfaces (2023)

A laser ablation system comprising a laser head providing a laser output; a flexible fiber optic cable optically coupled to the laser output and transmitting laser light; an output optics assembly including a nozzle through which laser light passes; an exhaust tube in communication with the nozzle; and a blower generating a vacuum on the exhaust tube. A method of decontaminating a surface comprising the following steps: providing an acousto-optic, Q-switched Nd:YAG laser light ablation system having a fiber optically coupled output optics assembly; and operating the laser light ablation system to produce an irradiance greater than 1.times.10.sup.7 W/cm.sup.2, and a pulse width between 80 and 170 ns.
MAXFAS: Mechatronic Arm Exoskeleton for Firearm Aim Stabilization (2016)

This article details the design, fabrication, and application of a mechatronic arm exoskeleton for firearm aim stabilization (MAXFAS), which senses and damps involuntary tremors in the arm. Human subject experiments were carried out using the device in a simulated shooting and aiming task. Results indicate that MAXFAS reduced arm tremors and improved shooting performance while wearing the device. Residual performance improvement after removing the device and possible training function of MAXFAS will also be discussed.
Learning Spatial Object Localization from Vision on a Humanoid Robot (2012)

We present a combined machine learning and computer vision approach for robots to localize objects. It allows our iCub humanoid to quickly learn to provide accurate 3D position estimates (in the centimetre range) of objects seen. Biologically inspired approaches, such as Artificial Neural Networks (ANN) and Genetic Programming (GP), are trained to provide these position estimates using the two cameras and the joint encoder readings. No camera calibration or explicit knowledge of the robot's kinematic model is needed. We find that ANN and GP are not just faster and have lower complexity than traditional techniques, but also learn without the need for extensive calibration procedures. In addition, the approach is localizing objects robustly, when placed in the robot's workspace at arbitrary positions, even while the robot is moving its torso, head and eyes.
The Sharing Tracker: Using Ideas from Cache Coherence Hardware to Reduce Off-Chip Memory Traffic with Non-Coherent Caches (2010)

Graphics Processing Units (GPUs) have recently emerged as a new platform for high performance, general-purpose computing. Because current GPUs employ deep multithreading to hide latency, they only have small, per-core caches to capture reuse and eliminate unnecessary off-chip accesses. This paper shows that for general-purpose workloads, the ability to copy cache lines between private caches captures inter-core temporal locality and provides substantial reductions in off-chip bandwidth requirements. Unlike hardware cache coherence, a sharing tracker only needs to track cache lines in the private caches imprecisely, because it is only a performance hint. This simplifies the implementation and is so effective at capturing inter-core reuse that the L2 can be eliminated entirely. The sharing tracker is motivated by but not specific to the GPU and could be used in other manycore organizations.
Ag3PO4/CoFe2O4 magnetic nanocomposite: synthesis, characterization and applications in catalytic reduction of nitrophenols and sunlight-assisted photocatalytic degradation of organic dye pollutants (2017)

A novel magnetically recyclable Ag<sub>3</sub>PO<sub>4</sub>/CoFe<sub>2</sub>O<sub>4</sub> nanocomposite was synthesized by a facile hydrothermal method and its photocatalytic/catalytic performance for the degradation of organic dyes or reduction of nitro compounds was investigated.
Deep multi-path network integrating incomplete biomarker and chest CT data for evaluating lung cancer risk (2021)

Clinical data elements (CDEs) (e.g., age, smoking history), blood markers and chest computed tomography (CT) structural features have been regarded as effective means for assessing lung cancer risk. These independent variables can provide complementary information and we hypothesize that combining them will improve the prediction accuracy. In practice, not all patients have all these variables available. In this paper, we propose a new network design, termed as multi-path multi-modal missing network (M3Net), to integrate the multi-modal data (i.e., CDEs, biomarker and CT image) considering missing modality with multiple paths neural network. Each path learns discriminative features of one modality, and different modalities are fused in a second stage for an integrated prediction. The network can be trained end-to-end with both medical image features and CDEs/biomarkers, or make a prediction with single modality. We evaluate M3Net with datasets including three sites from the Consortium for Molecular and Cellular Characterization of Screen-Detected Lesions (MCL) project. Our method is cross validated within a cohort of 1291 subjects (383 subjects with complete CDEs/biomarkers and CT images), and externally validated with a cohort of 99 subjects (99 with complete CDEs/biomarkers and CT images). Both cross-validation and external-validation results show that combining multiple modality significantly improves the predicting performance of single modality. The results suggest that integrating subjects with missing either CDEs/biomarker or CT imaging features can contribute to the discriminatory power of our model (p < 0.05, bootstrap two-tailed test). In summary, the proposed M3Net framework provides an effective way to integrate image and non-image data in the context of missing information.
A compact high gain planar microstrip array for mobile satellite communication (1994)

This paper describes the design and development of a low profile phased array suitable for INMARSAT Standard-M vehicular satellite communications. The array consists of twelve dual layer elements symmetrically positioned on a circular disk. The lower microstrip patches are fed directly to radiate right-handed circular polarization while the upper patches act as parasitic elements. Optimization has been carried out to improve the impedance bandwidth and to enhance the radiation characteristics. The array is designed to yield a fixed beam in the middle of the required elevation coverage region and is mechanically rotated in the azimuth plane. Its performance has been characterized within the frequency bands 1530–1559 MHz for receive and 1626.5–1660.5 MHz for transmit.
Machine protection (2021)

Since the previous TDR version 0.1, the hardware development has made significant progress. The universal quench detection system, CLIQ and energy extraction system prototypes have been successfully produced and tested and first units have been successfully deployed and used in SM18. This progress is reflected in the Sections below and some of the previously retained options have therefore been removed. In addition, the development of the quench heater power supplies for the HL-LHC is well advanced, which is shown in the respective Section below. Chapter 6 was updated following the approval of layout changes to the triplet circuit and an additional Section on cold diodes was added, as they have been adopted within the HL-LHC baseline. Finally, two new sources for very fast failures have been identified and studied in the past years, which is presented in the Section on fast failures.
3D TV (2004)

Three-dimensional TV is expected to be the next revolution in the history of television. We implemented a 3D TV prototype system with real-time acquisition, transmission, and 3D display of dynamic scenes. We developed a distributed, scalable architecture to manage the high computation and bandwidth demands. Our system consists of an array of cameras, clusters of network-connected PCs, and a multi-projector 3D display. Multiple video streams are individually encoded and sent over a broadband network to the display. The 3D display shows high-resolution (1024 × 768) stereoscopic color images for multiple viewpoints without special glasses. We implemented systems with rear-projection and front-projection lenticular screens. In this paper, we provide a detailed overview of our 3D TV system, including an examination of design choices and tradeoffs. We present the calibration and image alignment procedures that are necessary to achieve good image quality. We present qualitative results and some early user feedback. We believe this is the first real-time end-to-end 3D TV system with enough views and resolution to provide a truly immersive 3D experience.
Validation of Noninvasive Assessment of Pulmonary Gas Exchange in Patients with Chronic Obstructive Pulmonary Disease during Initial Exposure to High Altitude (2023)

Investigation of pulmonary gas exchange efficacy usually requires arterial blood gas analysis (aBGA) to determine arterial partial pressure of oxygen (mPaO<sub>2</sub>) and compute the Riley alveolar-to-arterial oxygen difference (A-aDO<sub>2</sub>); that is a demanding and invasive procedure. A noninvasive approach (AGM100), allowing the calculation of PaO<sub>2</sub> (cPaO<sub>2</sub>) derived from pulse oximetry (SpO<sub>2</sub>), has been developed, but this has not been validated in a large cohort of chronic obstructive pulmonary disease (COPD) patients. Our aim was to conduct a validation study of the AG100 in hypoxemic moderate-to-severe COPD. Concurrent measurements of cPaO<sub>2</sub> (AGM100) and mPaO<sub>2</sub> (EPOC, portable aBGA device) were performed in 131 moderate-to-severe COPD patients (mean ±SD FEV<sub>1</sub>: 60 ± 10% of predicted value) and low-altitude residents, becoming hypoxemic (i.e., SpO<sub>2</sub> < 94%) during a short stay at 3100 m (Too-Ashu, Kyrgyzstan). Agreements between cPaO<sub>2</sub> (AGM100) and mPaO<sub>2</sub> (EPOC) and between the O<sub>2</sub>-deficit (calculated as the difference between end-tidal pressure of O<sub>2</sub> and cPaO<sub>2</sub> by the AGM100) and Riley A-aDO<sub>2</sub> were assessed. Mean bias (±SD) between cPaO<sub>2</sub> and mPaO<sub>2</sub> was 2.0 ± 4.6 mmHg (95% Confidence Interval (CI): 1.2 to 2.8 mmHg) with 95% limits of agreement (LoA): -7.1 to 11.1 mmHg. In multivariable analysis, larger body mass index (<i>p</i> = 0.046), an increase in SpO<sub>2</sub> (<i>p</i> < 0.001), and an increase in PaCO<sub>2</sub>-PETCO<sub>2</sub> difference (<i>p</i> < 0.001) were associated with imprecision (i.e., the discrepancy between cPaO<sub>2</sub> and mPaO<sub>2</sub>). The positive predictive value of cPaO<sub>2</sub> to detect severe hypoxemia (i.e., PaO<sub>2</sub> ≤ 55 mmHg) was 0.94 (95% CI: 0.87 to 0.98) with a positive likelihood ratio of 3.77 (95% CI: 1.71 to 8.33). The mean bias between O<sub>2</sub>-deficit and A-aDO<sub>2</sub> was 6.2 ± 5.5 mmHg (95% CI: 5.3 to 7.2 mmHg; 95%LoA: -4.5 to 17.0 mmHg). AGM100 provided an accurate estimate of PaO<sub>2</sub> in hypoxemic patients with COPD, but the precision for individual values was modest. This device is promising for noninvasive assessment of pulmonary gas exchange efficacy in COPD patients.
Biodiversity and distribution of polar freshwater DNA viruses (2015)

Viruses constitute the most abundant biological entities and a large reservoir of genetic diversity on Earth. Despite the recent surge in their study, our knowledge on their actual biodiversity and distribution remains sparse. We report the first metagenomic analysis of Arctic freshwater viral DNA communities and a comparative analysis with other freshwater environments. Arctic viromes are dominated by unknown and single-stranded DNA viruses with no close relatives in the database. These unique viral DNA communities mostly relate to each other and present some minor genetic overlap with other environments studied, including an Arctic Ocean virome. Despite common environmental conditions in polar ecosystems, the Arctic and Antarctic DNA viromes differ at the fine-grain genetic level while sharing a similar taxonomic composition. The study uncovers some viral lineages with a bipolar distribution, suggesting a global dispersal capacity for viruses, and seemingly indicates that viruses do not follow the latitudinal diversity gradient known for macroorganisms. Our study sheds light into the global biogeography and connectivity of viral communities.
Human–Robot Collaboration Based on Motion Intention Estimation (2013)

In this paper, adaptive impedance control is proposed for a robot collaborating with a human partner, in the presence of unknown motion intention of the human partner and unknown robot dynamics. Human motion intention is defined as the desired trajectory in the limb model of the human partner, which is extremely difficult to obtain considering the nonlinear and time-varying property of the limb model. Neural networks are employed to cope with this problem, based on which an online estimation method is developed. The estimated motion intention is integrated into the developed adaptive impedance control, which makes the robot follow a given target impedance model. Under the proposed method, the robot is able to actively collaborate with its human partner, which is verified through experiment studies.
ChemInform Abstract: ANTIBACTERIAL PEPTIDE DERIVATIVES. PART IV. Nα‐HYDROXYACYLATED DERIVATIVES OF L‐LYSINE AND L‐ORNITHINE (1979)

Abstract Kondensation der Komponenten (II) und (III) [→(IV)] und nachfolgende Schutzgruppenabspaltung liefern die acylierten Aminosäureester (V); weiterhin werden die acylierten Dipeptidester (IX) dargestellt (kondensation der Komponenten (II) und (VI) [→(VIIa) bzw. (VIIb)] und nachfolgende Abspaltung der Na‐Schutzgruppe geben die Ester‐hydrochloride (VIIc) bzw. (VIId), die durch Kondensation mit (III) [→(VIII)] und nachfolgende Schutzgruppenabspal‐ tung in (IX) übergeführt werden).
The Lys-Specific Molecular Tweezer, CLR01, Modulates Aggregation of the Mutant p53 DNA Binding Domain and Inhibits Its Toxicity (2015)

The tumor suppressor p53 plays a unique role as a central hub of numerous cell proliferation and apoptotic pathways, and its malfunction due to mutations is a major cause of various malignancies. Therefore, it serves as an attractive target for developing novel anticancer therapeutics. Because of its intrinsically unstable DNA binding domain, p53 unfolds rapidly at physiological temperature. Certain mutants shift the equilibrium toward the unfolded state and yield high-molecular weight, nonfunctional, and cytotoxic β-sheet-rich aggregates that share tinctorial and conformational similarities with amyloid deposits found in various protein misfolding diseases. Here, we examined the effect of a novel protein assembly modulator, the lysine (Lys)-specific molecular tweezer, CLR01, on different aggregation stages of misfolded mutant p53 in vitro and on the cytotoxicity of the resulting p53 aggregates in cell culture. We found that CLR01 induced rapid formation of β-sheet-rich, intermediate-size p53 aggregates yet inhibited further p53 aggregation and reduced the cytotoxicity of the resulting aggregates. Our data suggest that aggregation modulators, such as CLR01, could prevent the formation of toxic p53 aggregates.
Sound analysis and extraction of data from Smart Contract (2023)

Abstract With the addition of multiple blockchain platforms in the ecosystem, the Dapp owners need to migrate their smart contracts from one platform to another to remain competitive , cost-effective, and secure. A smart contract is a piece of code that contain logic and data. To migrate a smart contract, whether it’s on the same blockchain platform or a different one, we need both its source code that represents the logic and data which indicate the state of the contract. The source code can be easily set up, but to complete the migration, we have to extract the current state of the contract. In this paper, we have developed an advanced state extraction technique that uses static analysis to analyze the smart contract’s call graph and events, and extracts the entire storage state from the storage trie, along with the proper associations across function calls, enabling users to visualize, manage, and transform the state as desired for migration. The soundness of the extracted state was confirmed using the method of abstract interpretation. Further, the migration adapter is designed that transform extracted state into slot-value pair and migrated it to the target blockchain. Our new approach has allowed us to analyze 14% more smart contracts with the extraction of 15% more data from 67,993 contracts, and migrate some of them to the Polygon test-net.
MRI-derived g-ratio and lesion severity in newly diagnosed multiple sclerosis (2021)

Myelin loss is associated with axonal damage in established multiple sclerosis. This relationship is challenging to study <i>in vivo</i> in early disease. Here, we ask whether myelin loss is associated with axonal damage at diagnosis by combining non-invasive neuroimaging and blood biomarkers. We performed quantitative microstructural MRI and single-molecule ELISA plasma neurofilament measurement in 73 patients with newly diagnosed, immunotherapy naïve relapsing-remitting multiple sclerosis. Myelin integrity was evaluated using aggregate g-ratios, derived from magnetization transfer saturation and neurite orientation dispersion and density imaging diffusion data. We found significantly higher g-ratios within cerebral white matter lesions (suggesting myelin loss) compared with normal-appearing white matter (0.61 versus 0.57, difference 0.036, 95% CI: 0.029-0.043, <i>P</i> < 0.001). Lesion volume (Spearman's rho r<sub>s</sub>= 0.38, <i>P</i> < 0.001) and g-ratio (r<sub>s</sub>= 0.24, <i>P</i> < 0.05) correlated independently with plasma neurofilament. In patients with substantial lesion load (<i>n</i> = 38), those with higher g-ratio (defined as greater than median) were more likely to have abnormally elevated plasma neurofilament than those with normal g-ratio (defined as less than median) [11/23 (48%) versus 2/15 (13%), <i>P</i> < 0.05]. These data suggest that, even at multiple sclerosis diagnosis, reduced myelin integrity is associated with axonal damage. MRI-derived g-ratio may provide useful additional information regarding lesion severity and help to identify individuals with a high degree of axonal damage at disease onset.