gebhart/patrepeval huggingface dataset:
Material parameters in a simulation of metal sheet stamping (2009)

The paper presents a methodology to tackle the problem of new materials, such as high-strength steels, used in industrial manufacturing. This methodology, which uses the finite element method (FEM), is based on two main ideas: determining the material properties as accurately as possible and automating the FEM simulation as much as possible. The main tool to solve these problems is an application designed to assist die stamp designers. Such an application can be used by anyone, even with no knowledge about finite elements, and does not need user participation. This fact makes the program very powerful and allows a procedure to be defined to obtain the values of the properties of an unknown material, which combines finite element simulations with real experimental results. The paper presents the developed application as well as the procedure used to determine the material properties. By combining both aspects, it is possible to simulate any stamping process, allowing the designer to obtain much information in the earlier stages of design. This paper fulfils an identified need in the manufacturing industry. In fact, the proposed application is currently being used by a manufacturer of automotive components.
Care Provision and Prescribing Practices of Physicians Treating Children and Adolescents With ADHD (2017)

Differences were found by physician type in care of children with ADHD. Additional studies are needed to understand clinical consequences of these differences and the implications for care coordination across provider specialties.
Универсальные вакцины против гриппа. Разработки, перспективы использования (2012)

The review analyzes the developments of genetic engineering influenza vaccines based on the conservative epitopes of viral surface proteins, such as hemagglutinin, neuraminidase, ectodomain of matrix protein M2. It estimates the capacity of the vaccines to induce an immune response to a wide variety of influenza viruses, considers ways to increase the immunogenicity and protective properties of the vaccines, based on the conservative epitopes of viral surface proteins, and prospects for their use to prevent influenza.
An Overview of Consumer Data and Credit Reporting (2003)

For some time, the Board of Governors of the Federal Reserve System has sought to obtain more detailed and timely information on the debt status, loan payment behavior, and overall credit quality of U.S. consumers. For decades, information of this type has been gathered by credit reporting companies primarily to assist creditors in evaluating the credit quality of current and prospective customers. To evaluate the potential usefulness of these data, the Federal Reserve Board engaged one of the three national consumer reporting companies to supply the credit records, without personal identifying information, of a nationally representative sample of individuals. This article describes the way the credit reporting companies compile and report their data and gives background on the regulatory structure governing these activities. This description is followed by a detailed look at the information collected in credit reports. Key aspects of the data that may be incomplete, duplicative, or ambiguous as they apply to credit evaluation are highlighted in the analysis. The article concludes with a discussion of steps that might be taken to address some of the issues identified.
Clinical Characterization of Data-Driven Diabetes Clusters of Pediatric Type 2 Diabetes (2023)

Utilizing clinical measures gathered at the time of diabetes diagnosis can be used to identify subgroups of pediatric T2D with prognostic value. Consequently, this advancement contributes to the progression and wider implementation of precision medicine in diabetes management.
Towards Adaptive Event Detection Techniques for the Twitter Social Media Data Stream (2015)

published
Methanobactin from methanotrophs: genetics, structure, function and potential applications (2020)

Aerobic methane-oxidizing bacteria of the Alphaproteobacteria have been found to express a novel ribosomally synthesized post-translationally modified polypeptide (RiPP) termed methanobactin (MB). The primary function of MB in these microbes appears to be for copper uptake, but MB has been shown to have multiple capabilities, including oxidase, superoxide dismutase and hydrogen peroxide reductase activities, the ability to detoxify mercury species, as well as acting as an antimicrobial agent. Herein, we describe the diversity of known MBs as well as the genetics underlying MB biosynthesis. We further propose based on bioinformatics analyses that some methanotrophs may produce novel forms of MB that have yet to be characterized. We also discuss recent findings documenting that MBs play an important role in controlling copper availability to the broader microbial community, and as a result can strongly affect the activity of microbes that require copper for important enzymatic transformations, e.g. conversion of nitrous oxide to dinitrogen. Finally, we describe procedures for the detection/purification of MB, as well as potential medical and industrial applications of this intriguing RiPP.
Microparticulate Systems for the Delivery of Proteins and Vaccines (2020)

Stability of Proteins and Their Delivery from Biodegradable Polymer Microspheres, Steven S. Schwenderman Injectable Biodegradable Microspheres for Vaccine Delivery, Thomas Kissel and Regina Koneberg Preparation of Microparticulates Using Supercritical Fluids, Barbara L. Knutson, Pablo G. Debenedetti, and Jean W. Tom Polyphoshazene Hydrogel Microspheres for Protein Delivery, Alexander K. Andrianov and Lendon G. Payne Lipospheres for Vaccine Delivery, Shimon Ameselem, Carl R. Alving, and Abraham J. Domb The Characterization of Polyanhydride Microspheres, Anette Brunner and Achim Gopferich Nanoparticulate Drug Carrier Technology, Maria J. Alonso Biodistribution of Surface-Modified Liposomes and Particles, Vladimir P. Torchilin and Vladimir S. Trubetskoy Poly(Etylene Glycol)-Coated Biodegradable Nanospheres for Intravenous Drug Administration, Ruxandra Gref, Yoshiharu Minamitake, and Maria Teresa Peracchia, and Robert Langer Polymerized and Microencapsulated Liposomes for Oral Delivery and Vaccination, Jun,ichi Okada Pharmacokinetics of Microparticulate Systems, Pravin R. Chaturvedi Adjuvant-Active Polymeric Microparticulate Vaccine-Delivery Systems, Douglas Kline, Justin Hanes, and Robert Langer Oral Vaccination by Microspheres, Hitesh R. Bnagat, Paresh S. Dalal, and Ranjani Nellore Biodegradable Gelatin Microspheres for Drug Delivery to Macrophages, Yasuhiko Tabata and Yoshito Ikada Bioadhesive Liposomes for Topical Treatment of Wounds, Rimona Margalit Ultrasound-Triggered Delivery of Peptides and Proteins from Microspehres, Joseph Kost Polyacrylate Microcapsules for Cell Delivery, Julia E. Babensee and Michael V. Sefton
A study of modern trends in traditional food security methods of rural areas with reference to the north-west slope in Sinharaja forest (2010)

The world heritage Sinharaja forest in Sri Lanka is situated in the South- West region of the island between northern latitude 6° 21 ' and 6° 27' and southern longitude 80° 21' and 80° 34'. This study focuses on analyzing the traditional methods of food security practiced in rural areas, with the special focus on the North - West slope of Sinharaja, which spreads over 11187 hectares. The research problem is 'how the communities residing at peripheral areas of tropical rain forests have used indigenous knowledge concerning food security over a long period?' Six villages at the periphery of North-West slope of Sinharaja namely Kudawa, Pitakele, Kongahakanda, Petiyakanda, Ketalapattala and Kosgulana were selected for the study. At the end of 2009, about 975 people were living in these six villages. Methods used for data collection were open interview and direct observation. This study has recognized the traditional food security methods in the study area, types of food preserved, the way the old methods are used for modern needs, and factors that have persuade villagers to secure food. This study implies that with the change in land consumption styles, foods that are preserved earlier by people such as cassava, jack, cucumber, kurakkan, thampala, el vee, amu etc., have been neglected. With the use of scrub jungles for tea cultivation, treacle varieties such as kitul treacle are faced with extinction. As rural community build modern houses instead of traditional houses, background of food preserving is gradually declining. The villagers of the study area have used various methods to secure food and these methods are influenced by various human and material factors.
Metalle in Biologie und Medizin, III. Bismutlactat: Darstellung und Strukturchemie eines Hydroxycarboxylat‐Komplexes (1992)

Metals in Biology and Medicine, III. — Bismuth Lactate: Synthesis and Structure of a Hydroxycarboxylate Complex As a compound of medical relevance, bismuth ( S )‐lactate was synthesized and structurally characterized (single‐crystal X‐ray diffraction). Exploiting the versatile coordination chemistry of carboxylate groups (chelating and bridging ligands), the crystal structure is based upon a three‐dimensional network, showing bismuth in a high coordination number environment.
Digging Up Tangled Roots: Feminism and Resistance to White Working-Class Culture (1999)

If it is true that we can only look from a position of (relative) safety/confidence/power, it is no surprise that I came to the life history process after my father's death in October 1990, and a three-year period during which I experienced a sudden and sharp sense of my own mortality. Life, health and professional circumstances had combined to create a crisis of confidence and meaning.1 In 1993, I found myself simultaneously letting go of my institutional academic position (if not my academic identity), and starting my life history.2 Later the same year, at a women's art exhibition entitled Women Remember/ Women in Conflict, I encountered the work of artist Irene Runayker.3 Written across one of her mixed media images, I read: In times of bereavement and broken dreams, our camouflage frays, decays and our history shows through. (The Forty Five Stars, Taoist text, cited in Runayker, 1994) Life history process was precipitating a sense of opening rather than closure, expansion rather than contraction and withdrawal, hope rather than depression. This was academic work, but also an important part of my personal recovery and renewal.
{Fully-Automatic Bayesian Piecewise Sparse Linear Models} (2014)

Piecewise linear models (PLMs) have been widely used in many enterprise machine learning problems, which assign linear ex-perts to individual partitions on feature spaces and express whole models as patches of local experts. This paper addresses si-multaneous model selection issues of PLMs; partition structure determination and feature selection of individual experts. Our contri-butions are mainly three-fold. First, we ex-tend factorized asymptotic Bayesian (FAB) inference for hierarchical mixtures of experts (probabilistic PLMs). FAB inference offers penalty terms w.r.t. partition and expert complexities, and enable us to resolve the model selection issue. Second, we propose posterior optimization which signicantly im-proves predictive accuracy. Roughly speak-ing, our new posterior optimization miti-gates accuracy degradation due to a gap be-tween marginal log-likelihood maximization and predictive accuracy. Third, we present an application of energy demand forecasting as well as benchmark comparisons. The ex-periments show our capability of acquiring compact and highly-accurate models. 1
Gigabit wireless/wired transmission over full colorless WDM-PON platform using optical sideband slicing (2011)

A new architecture, which is transmitting a gigabit millimeter-wave band data over wavelength division multiplexed-passive optical network (WDM-PON) platform, is proposed. It is very important to transmit a broadband data in the millimeter-wave band without a significant change of the conventional WDM-PON architecture because a drastic alteration can make its scheme be an expensive one. Here, a sliced optical sideband based on a 50-GHz spaced arrayed waveguide grating (AWG) is used to generate a millimeter-wave band signal as well as a baseband one. Error free transmissions (wired data: BER of 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-12</sup> , wireless data: BER of 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-9</sup> ) of a 2.5-Gb/s wired data and a 1.25-Gb/s wireless data are achieved simultaneously.
Abstract 5507: Investigation of the effects of alterations in the glutamate receptor, GRIK2 on osteosarcoma tumorigenesis (2017)

Abstract Osteosarcoma is a primary, malignant bone tumour mainly affecting young adults with a five-year survival rate of 60-70% depending on presentation of metastasis at diagnosis. Tumours are marked by genetic instability and heterogeneity and for this reason, molecular subtypes have yet to be characterized. Survival rates have remained consistent over the past few decades and novel molecular targets for treatment are needed. Current genomic strategies have identified recurrent copy number alterations. In a study of 44 flash frozen osteosarcoma tumours which were obtained at the time of biopsy and 25 blood-matched samples we identified recurrent copy number losses including a region at 6q16.3 in 14% of tumours. Focal deletions were observed in the 5’ intergenic space and first intron of the GRIK2 gene and do not overlap with any coding sequence. The relationship between alterations in this region and osteosarcoma tumourigenesis has yet to be explored in depth. GRIK2 encodes an ionotropic glutamate receptor that has been implicated as a tumour suppressor in gastric cancer. An interesting feature of the tumours was the overlap of focal deletions with a SETDB1 histone methyltransferase binding site indicating a potential connection with epigenetic regulation of GRIK2. The goal of this study is to examine the effects of non-coding, focal deletions on GRIK2 gene expression, function and regulation in osteosarcoma cells. GRIK2 transcript levels were measured in osteosarcoma tumours and cell lines using qRT-PCR. Functional assays were performed to characterize the role of GRIK2 in osteosarcoma cell proliferation, migration and apoptosis in vitro. Gene editing with CRISPR/cas9 was performed to examine the link between non-coding deletions and GRIK2 expression. GRIK2 transcript levels varied in tumours; several tumours with focal deletions had increased transcript levels relative to cell lines which demonstrated low expression levels. Due to the observation of low transcript levels, a gain of function approach was employed to examine GRIK2 function in vitro. Overexpression of GRIK2 decreased proliferation, migration and increased apoptosis in osteosarcoma cells. Gene editing of the SETDB1 binding site resulted in increased GRIK2 transcript levels relative to untreated cells. This study suggests that non-coding focal deletions are linked to high expression levels of GRIK2 which may confer a less aggressive phenotype and are involved in epigenetic regulation of the gene. Citation Format: Justin G. Mayers, Nalan Gokgoz, Jay S. Wunder, Irene L. Andrulis. Investigation of the effects of alterations in the glutamate receptor, GRIK2 on osteosarcoma tumorigenesis [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 5507. doi:10.1158/1538-7445.AM2017-5507
Mathematical Model of Long Pile Synthetic Turf for Calculating Shock Attenuation Properties in Various Conditions (2015)

The purpose of this study is to propose the mathematical model for long pile synthetic turf which can be used for evaluating the shock attenuation properties and to investigate the shock attenuation properties by using modeling and simulation method in various impact conditions. Although there were some improvements in the impact test for the long pile synthetic turf by adding the rod to the test foot for stable movement during impact, the unstable data are still observed because of the irregularity of the infill surface which can not be eliminated from the experiments for the long pile synthetic turf. Therefore, ten trials were performed to identify in each condition, i.e. the combination of 5 impact areas and 10 dropping heights makes 500 trials were performed for parameter identification. And the proposed model in this study is modified from the previous one. Finally, the calculated parameters could distinguish the difference of hardness and also simulate the dropping mass-spring model stably. As the results, various conditions, such as drop mass, impact duration, were simulated to acquire the FR values in each condition.
Model Quality Assessment and Model Mismatch Detection: A Temporal Smoothness Regularization Approach (2018)

Most industrial controllers are designed based on process models, and hence the closed-loop performance closely depends on the model quality. Since process dynamics variations are inevitable in practical applications, plant-model quality assessment is necessary so that model mismatch can be detected in time. In this article, a novel method based on temporal smoothness regularization is presented for model quality assessment. The linear time variant (LTV) model structure is applied to approximate the process dynamics. To avoid an overfitted model, temporal smoothness regularization is imposed on the model parameter changes so that model generalization ability is guaranteed. On the basis of the LTV model structure, a data-based model quality assessment approach is proposed, and the applicability is demonstrated through representative case studies.
Biochemical screening for SARS-CoV-2 main protease inhibitors (2020)

The Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) pandemic represents a global challenge. SARS-CoV-2's ability to replicate in host cells relies on the action of its non-structural proteins, like its main protease (Mpro). This cysteine protease acts by processing the viruses' precursor polyproteins. As proteases, together with polymerases, are main targets of antiviral drug design, we here have performed biochemical high throughput screening (HTS) with recombinantly expressed SARS-CoV-2 Mpro. A fluorescent assay was used to identify inhibitors in a compound library containing known drugs, bioactive molecules and natural products. These screens led to the identification of 13 inhibitors with IC50 values ranging from 0.2 μM to 23 μM. The screens confirmed several known SARS-CoV Mpro inhibitors as inhibitors of SARS-CoV-2 Mpro, such as the organo-mercuric compounds thimerosal and phenylmercuric acetate. Benzophenone derivatives could also be identified among the most potent screening hits. Additionally, Evans blue, a sulfonic acid-containing dye, could be identified as an Mpro inhibitor. The obtained compounds could be of interest as lead compounds for the development of future SARS-CoV-2 drugs.
An IoT empowered flexible chipless RFID tag for low cost item identification (2017)

This paper demonstrates the study and design of a compact and inexpensive chipless RFID tag with increased data capacity on flexible substrates like plastic or paper. Along with the integrated antennas, the overall size of this tag is similar to that of a credit card. In this case, polarization diversity is used to provide a bit capacity of up to 10 bits in the UWB short range RADAR band of 22-26.5 GHz. An interrogation process of the printed tag prototype to extract the encoded information is demonstrated here and the measured results ensure the validity of the proposed design.
DESIGN TOOL FOR CRYOGENIC THERMAL INSULATION SYSTEMS (2008)

Thermal isolation of low-temperature systems from ambient environments is a constant issue faced by practitioners of cryogenics. For energy-efficient systems and processes to be realized, thermal insulation must be considered as an integrated system, not merely an add-on element. A design tool to determine the performance of insulation systems for comparative trade-off studies of different available material options was developed. The approach is to apply thermal analysis to standard shapes (plane walls, cylinders, spheres) that are relatively simple to characterize with a one-dimensional analytical or numerical model. The user describes the system hot and cold boundary geometry and the operating environment. Basic outputs such as heat load and temperature profiles are determined. The user can select from a built-in insulation material database or input user defined materials. Existing information has been combined with the new experimental thermal conductivity data produced by the Cryogenics Test Laboratory for cryogenic and vacuum environments, including high vacuum, soft vacuum, and no vacuum. Materials in the design tool include multilayer insulation, aerogel blankets, aerogel bulk-fill, foams, powders, composites, and other insulation system constructions. A comparison of the design tool to a specific composite thermal insulation system is given.
Imaging of prostate cancer with PET/CT using (18)F-Fluorocholine. (2015)

While (18)F-Fluorodeoxyglucose ((18)F-FDG) Positron-Emission Tomography (PET) has limited value in prostate cancer (PCa), it may be useful for specific subgroups of PCa patients with hormone-resistant poorly differentiated cell types. (18)F-Fluorocholine ((18)F-FCH) PET/CT has been increasingly used in primary and recurrent PCa and has been shown to add valuable information. Although there is a correlation between the foci of activity and the areas of malignancy in the prostate gland, the clinical value of (18)F-FCH is still controversial for detection of the malignant focus in the prostate. For the T-staging of PCa at diagnosis the value of (18)F-FCH is limited. This is probably due to limited resolution of PET system and positive findings in benign prostate diseases. Conversely, (18)F-FCH PET/CT is a promising imaging modality for the delineation of local and distant nodal recurrence and bone metastases and is poised to have an impact on therapy management. In this review, recent studies of (18)F-FCH PET/CT in PCa are summarized.
DECOMPOSITION OF SOME CENTRAL SEPARABLE ALGEBRAS (2001)

If an Azumaya algebra A is a homomorphic image of a finite group ring RG where G is a direct product of subgroups then A can be decomposed into subalgebras A(sub)i which are homomorphic images of subgroup rings of RG. This result is extended to projective Schur algebras, and in this case behaviors of 2-cocycles will play major role. Moreover considering the situation that A is represented by Azumaya group ring RG, we study relationships between the representing groups for A and A(sub)i.
Plasma printing: patterned surface functionalisation and coating at atmospheric pressure (2004)

A new plasma-based micropatterning technique, here referred to as plasma printing, combines the well known advantages given by the nonequilibrium character of a dielectric barrier discharge (DBD) and its operation inside small gas volumes with dimension between tens and hundreds of micrometres. The discharge is run at atmospheric pressure and can be easily implemented for patterned surface treatment with applications in biotechnology and microtechnology. In this work the local modification of dielectric substrates, e.g. polymeric films, is addressed with respect to coating and chemical functionalisation, immobilisation of biomolecules and area-selective electroless plating.