gebhart/patrepeval huggingface dataset:
Field emission studies from Nb surfaces relevant to SRF cavities (2004)

Enhanced field emission (EFE) presents the main impediment to higher acceleration gradients in superconducting rf (SRF) niobium (Nb) cavities for particle accelerators. A scanning field emission microscope was built at Jefferson Lab with the main objective of systematically investigating the sources of EFE from Nb surfaces. Various surface preparation techniques and procedures, including chemical etching, electropolishing, ultrasonic water rinse, high pressure water rinse, air-dry after methanol rinse, air-dry after water rinse in Class 10 cleanroom, were investigated. The capability and process variables for broad-area Nb surfaces to consistently reach field emission free or near field emission free performance at /spl sim/140 MV/m have been experimentally demonstrated using the above techniques/procedures.
Identification of Two Distinct Isoforms of the Guanine Nucleotide Binding Protein Go in Neuroblastoma × Glioma Hybrid Cells: Independent Regulation During Cyclic AMP‐Induced Differentiation (1990)

Three distinct antipeptide antisera generated against synthetic peptides that represent parts of the primary sequence of the alpha-subunit of the (pertussis toxin-sensitive) guanine nucleotide binding protein G0 were used in two-dimensional immunoblots of membranes of neuroblastoma X glioma (NG108-15) cells. Each antiserum identified two distinct polypeptides of some 39 kDa. These had apparent isoelectric points of 5.5 and 5.8. Differentiation of NG108-15 cells in response separately to dibutyryl cyclic AMP (cAMP), 8-bromo cAMP, forskolin, and prostaglandin E1 produced elevated levels of G0 alpha, as has previously been noted in one-dimensional immunoblots. Two-dimensional analysis demonstrated that the cAMP-induced increases in levels of G0 alpha were only of the more acidic isoform. The two isoforms were both substrates for pertussis toxin-catalysed ADP-ribosylation and did not appear to represent differentially phosphorylated forms of the same polypeptide. Separation of the two forms of G0 alpha could be achieved in one-dimensional sodium dodecyl sulphate-polyacrylamide gel electrophoresis when 4 M deionized urea was included in the resolving gel. The more slowly migrating band was the acidic form and corresponded exactly in mobility with the major form of G0 from both rat and mouse brain. There was no equivalent in brain of the more rapidly migrating form of G0 from the cells. In agreement with the data from two-dimensional gels, only the more slowly migrating form was expressed in considerably higher amounts following cAMP-induced differentiation of NG108-15 cells. Of these two forms of "G0," the acidic species is equivalent to G0 from brain, but the basic form is not identical with G0*, which has been purified from bovine brain.
Semiconductor Lasers Stabilized to Spectral Holes In Rare-Earth Crystals (2001)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text Thomas Böttger, Geoffrey J. Pryde, Nicholas M. Strickland, Peter B. Sellin, and Rufus L. Cone, "Semiconductor Lasers Stabilized to Spectral Holes In Rare-Earth Crystals," Optics & Photonics News 12(12), 23-23 (2001) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Structural abstractions of hypertext documents for Web-based retrieval (2002)

There have been conflicting views in the literature on the capability of tools and mechanisms for storing and accessing information over Internet. On one hand it has been claimed for a long time that World Wide Web offers a chaotic environment for Web agents to extract information because the description of a document by HTML is easily comprehensible by humans, but is not so by machines. On the other hand, it has been hypothesized that information is sufficiently structured to facilitate effective Web mining, especially for electronic catalogs. In this article we do not intend to take position on this matter, but rather investigate the performance of a search engine while indexing more logical elements of HTML documents and while increasing the scope of indexing process.
Bacteriophage Mu Mom protein responsible for DNA modification is a new member of the acyltransferase superfamily (2008)

Not available.
Proton Radiation Effects on the Analog Performance of Bulk n- and p-FinFETs (2015)

This paper presents an evaluation of the impact of 60 MeV Proton radiation on triple gate Bulk FinFETs, for both n and p types. The main focus is intrinsic voltage gain, threshold voltage and the OFF region drain current. The narrow nFinFET devices present an unexpected degradation of the drain current in the off-state region, which shows that the radiation affects severely the STI oxide resulting in a high parasitic conduction. The pFinFETs are more tolerant than the nFinFETs for environments that suffer from high-energy proton exposure.
Utilization and Metabolism of NAD by Haemophilus parainfluenzae (1988)

The utilization of exogenous nicotinamide adenine dinucleotide (NAD) by Haemophilus parainfluenzae was studied in suspensions of whole cells using radiolabelled NAD, nicotinamide mononucleotide (NMN), and nicotinamide ribonucleoside (NR). The utilization of these compounds by H. parainfluenzae has the following characteristics. (1) NAD is not taken up intact, but rather is degraded to NMN or NR prior to internalization. (2) Uptake is carrier-mediated and energy-dependent with saturation kinetics. (3) There is specificity for the beta-configuration of the glycopyridine linkage. (4) An intact carboxamide groups is required on the pyridine ring. The intracellular metabolism of NAD was studied in crude cell extracts and in whole cells using carbonyl-14C-labelled NR, NMN, NAD, nicotinamide, and nicotinic acid as substrates in separate experiments. A synthetic pathway from NR through NMN to NAD that requires Mg2+ and ATP was demonstrated. Nicotinamide was found as an end-product of NAD degradation. Nicotinic acid mononucleotide and nicotinic acid adenine dinucleotide were not found as intermediates. The NAD synthetic pathway in H. parainfluenzae differs from the Preiss-Handler pathway and the pyridine nucleotide cycles described in other bacteria.
Impact of the Wafer Quality on the Reliability of MOS Structure on the C-Face of 4H-SiC (2008)

We report on the reliability of the gate oxide on C-face of 4H-SiC. Constant current stress TDDB measurement shows that QBD of the gate oxide of f200 [μm] on C-face is as much as 18 [C/ cm2], which is much larger than the typical value (0.1[C/ cm2]) of that on Si-face of 4H-SiC. The lifetimes of the gate oxide under the electric field of 3[MV/cm] are roughly evaluated from the leakage characteristics and obtained QBD. The estimated lifetimes of the gate oxide of f600 [μm] are about 900 years. TDDB measurements of MOSs on two wafers, which have different dislocation densities, show that reliability of gate oxide on C-face is insensitive to the dislocation density. Meanwhile, reliability of the gate oxide is sensitive to the surface defect density: it is significantly degraded on the wafer, which has 2000 surface defects in a whole 2-inch wafer.
Differential Regulation of Human and Mouse Orphan Nuclear Receptor Small Heterodimer Partner Promoter by Sterol Regulatory Element Binding Protein-1 (2004)

Small heterodimer partner (SHP; NR0B2) is an unusual orphan nuclear receptor that lacks a conventional DNA-binding domain and acts as a modulator of transcriptional activities of a number of nuclear receptors. Herein, we report that the human SHP promoter (hSHP) is activated by sterol regulatory element-binding protein-1 (SREBP-1), which regulates the expression of various genes involved in cholesterol and fatty acid synthesis. Overexpression of SREBP-1 activated the human but not mouse SHP promoter, although SREBP-2 had little effect on the SHP promoter in CV-1 cells. Serial deletion reporter assays revealed that SREBP-1-responsive region is located within the sequences from -243 to -120 bp in the hSHP promoter. DNase I footprinting, gel shift assays, and chromatin immunoprecipitation assays demonstrated that SREBP-1 binds directly to the hSHP promoter. Site-directed mutagenesis made it clear that the hSHP promoter activation by SREBP-1 is mostly mediated by the SRE1 (-186 to -195 bp) in the hSHP promoter, which is not conserved in the mouse SHP promoter. Moreover, adenovirus-mediated overexpression of SREBP-1c/ADD-1 induced SHP mRNA expression and repressed CYP7A1 expression in HepG2 cells. Finally, we found that a four-nucleotide deletion (-195CT-GAdel) in the hSHP promoter, which is reported to be associated with altered body weight and insulin secretion in human, coincides with the SRE1. This mutation strongly decreased both basal and SREBP-1 dependent activities of the hSHP promoter, because of the reduced binding of SREBP-1 to the mutated SRE1. Overall, our results demonstrate a differential regulation of human and mouse SHP promoters by SREBP-1. We propose a possible role of SREBP-1 in the species differential regulation of cholesterol and bile acid homeostasis via a novel mechanism of up-regulation of the hSHP gene expression.
Influence of induced shear work on the properties of polyolefine nanocomposite pipes (2012)

Abstract The use of layered silicates is steadily growing in polymer processing due to their great potential of enhancing material properties. Depending on the particle structure (agglomerated, intercalated, or exfoliated), a significantly higher level of improvement of the material properties can be achieved. The degree of exfoliation is exceedingly linked with the residence time and shear energy induced during processing. These processing parameters themselves are depending on the type of processing technique and conditions. The influence on exfoliation rate and the needed values for processing nanocomposites are not known precisely, but would be of major interest according to an optimization of mechanical and physical properties. In this work, the effect of different processing techniques (compounding, extrusion, and injection molding) on the dispersion of the nanofiller is investigated. A specific shear energy is calculated by the induced shear energy and the residence time regarding the mass throughput for better comparison. The differences in the degree of exfoliation according to dissimilarity of the chosen processing techniques are compared via various methods such as internal pressure creep rupture test, longitudinal shrinkage, and tensile test. It is shown that the calculated values are correlating with good precision, especially for the extrusion process. POLYM. ENG. SCI., 2012. © 2012 Society of Plastics Engineers
Monitoring the quality of laboratories and the prevalence of resistance to antituberculosis drugs: Italy, 1998–2000 (2003)

In 1998 a network of 20 regional tuberculosis (TB) laboratories (the Italian Multicentre Study on Resistance to Antituberculosis drugs (SMIRA) network) was established in Italy to implement proficiency testing and to monitor the prevalence of drug resistance nationwide. The network managed 30% of all TB cases reported in Italy each year. The aim of the present report is to describe: 1) the accuracy of drug-susceptibility testing in the network; 2) the prevalence of drug resistance for the period 1998-2000. Data were collected from the network laboratories. Sensitivity to streptomycin and ethambutol increased from the first survey (1998-1999) to the second survey (2000) from 87.7 to 91.9%. Specificity, predictive values for resistance and susceptibility, efficiency and reproducibility were consistent in both surveys. In previously untreated cases, the prevalence of multidrug-resistance was the same in both surveys (1.2%), while a slight decrease from the first to the second survey was observed for monoresistance to rifampicin (from 0.8 to 0.4%) and isoniazid (from 2.9 to 2%). The significant association found between isoniazid resistance and immigration is a useful indicator for both clinicians managing individual tuberculosis cases and public health services planning control strategies.
Distributed subchannel assignment in an OFDMA relay (2007)

The paper studies a distributed OFDMA system in which the transmitting nodes (source and relay) have access to channel information and to some interference-related information. Distributed subchannel allocation is modelled as a noncooperative game where the players are the source nodes. Channel-aware source nodes opportunistically select their subchannels while a channel-aware relay node assigns the input subchannels at relay to appropriate output subchannels in a way that maximizes the sum of utilities in terms of signal-to-noise ratio. Numerical examples illustrate the performance of distributed subchannel assignment; opportunistic channel allocation implies a trade-off between the average capacity and fairness.
The Vector Decomposition Problem for Elliptic and Hyperelliptic Curves. (2005)

Abstract. The group of m-torsion points on an elliptic curve, for a prime number m, forms a two-dimensional vector space. It was suggested and proven by Yoshida that under certain conditions the vector decomposition problem (VDP) on a two-dimensional vector space is at least as hard as the computational Diffie-Hellman problem (CDHP) on a one-dimensional subspace. In this work we show that even though this assessment is true, it applies to the VDP for m-torsion points on an elliptic curve only if the curve is supersingular. But in that case the CDHP on the one-dimensional subspace has a known sub-exponential solution. Furthermore, we present a family of hyperelliptic curves of genus two that are suitable for the VDP. Key words. Elliptic curve cryptography, Curves of genus two. 1
Mutual Mentoring on Projects – A Proposal to Combine the Advantage of Several Established Management Development Methods (1990)

While mentoring has obvious benefits to the protege, benefits to the mentor and to the organisation are often long term or invisible. A procedure named Mutual Mentoring on Projects is proposed which produces observable short‐term benefits for protege, mentor and organisation and minimum costs.
Extraction of Dispersive Material Parameters Using Vector Network Analyzers and Genetic Algorithms (2006)

A novel method to extract dispersive properties for dielectrics over a wide frequency range is proposed. This method is based on measuring scattering parameters for planar transmission lines and applying genetic algorithms. The scattering parameters are converted into ABCD matrix parameters. The complex propagation constant of the TEM wave inside the line is obtained from A-parameters of the ABCD matrix. For planar transmission lines, analytical or empirical formulas for dielectric loss, conductor loss, and phase constant are known. The genetic algorithm is then used to extract the Debye parameters for the dielectric substrates. FDTD modeling is used to verify the dispersive parameter extraction by comparing with the measurement
Differential Acylated Ghrelin, Peptide YY3–36, Appetite, and Food Intake Responses to Equivalent Energy Deficits Created by Exercise and Food Restriction (2011)

These findings suggest a mediating role of acylated ghrelin and PYY(3-36) in determining divergent feeding responses to energy deficits imposed by food restriction and exercise.
Reconstruction of the segmental mandibular defect (2012)

The microvascular transfer of free osteocutaneous flaps remains the standard of care, with the fibula flap the clear favorite. Review of the evolution of this flap for segmental mandibular reconstruction provides the bulk of the literature. Improvement on this standard of practice continues to be elusive, in large part because of the effects of associated radiation. Tissue engineering holds promise but no current practical application is available.
Supplementary Figure from Antitumor Activity of a Mitochondrial-Targeted HSP90 Inhibitor in Gliomas (2023)

Supplementary Figure from Antitumor Activity of a Mitochondrial-Targeted HSP90 Inhibitor in Gliomas
Crystal Structures of C94(CF3)20 and C96(C2F5)12 Reveal the Cage Connectivities in C94 (61) and C96 (145) Fullerenes (2009)

Perfluoroalkylation of a mixture of higher fullerenes has yielded the first direct proof of the cage connectivities in C94 (isomer 61) and C96 (isomer 145). The addition patterns of the RF groups on these fullerene cages, the largest to be structurally investigated to date, were determined by X-ray structure analyses of C94(CF3)20 (see structure; gray C, green F) and C96(C2F5)12.
Visualization Emergency Research Based on Mobile Mapping Technology (2015)

Abstract Considering the prevention and management of the major emergencies in China and the increasingly severe environmental security situations, a visualization emergency solution, based on a mobile mapping system is proposed. This paper studies the key technologies of a mobile mapping system in emergency management. It considers the design of a total factor and full-texture real map, which is measurable and can be marked through the mobile mapping technology. It also proposes the application of a real map in emergency cases, which has large practical significance.
The centriolar satellite protein Cep131 is important for genome stability (2012)

The centrosome acts as a centre for microtubule organisation and plays crucial roles in cell polarity, migration, growth and division. Cep131 has recently been described as a basal body component essential for cilium formation, but its function in non-ciliogenic cells is unknown. We identified human Cep131 (also known as AZI1) in a screen for regulators of genome stability. We show that centrosomal localisation of Cep131 is cell-cycle-regulated and requires both an intact microtubule network and a functional dynein-dynactin transport system. Cep131 is recruited to centriolar satellites by PCM1, and localised to the centriolar core region by both pericentrin and Cep290. Depletion of Cep131 results in a reduction in proliferation rate, centriole amplification, an increased frequency of multipolar mitosis, chromosomal instability and an increase in post-mitotic DNA damage. These data therefore highlight the importance of human Cep131 for maintaining genomic integrity.
Kinetics of reabsorption of nutrients in renal brush border membrane vesicles from rats with experimental ascending pyelonephritis. (1986)

The uptake of nutrients was investigated in the renal cortical brush border membrane (BBM) vesicles at different stages of ascending pyelonephritis. There was significant difference (p less than 0.05) in the uptake of D-glucose, L-alanine, L-aspartate, L-lysine and L-proline 3 days postinfection and onwards in both right unobstructed and left obstructed experimental kidneys as compared to the sham operated control. The uptake of D-glucose, L-lysine and L-proline was found to be significantly decreased (p less than 0.05) during the course of infection. While uptake of L-alanine and L-aspartate increased (p less than 0.05) in early stages and decreased (p less than 0.05) in later stages of infection. The differential effect was attributed to the compensatory measure and different kinds of transport systems for different types of amino acids.
Focal Fibrocartilaginous Dysplasia in the Upper Extremity (1997)

Summary: Focal fibrocartilaginous dysplasia is a benign lesion known to cause tibia vara in young children. To date, this lesion has been recognized in only the proximal medial tibia. This study reports two additional cases of focal fibrocartilaginous dysplasia occurring in the long bones of the upper extremity. The clinical presentation, radiographic appearance, histopathology, and natural history of focal fibrocartilaginous dysplasia in the humerus and ulna are analogous to published descriptions involving the tibia. Spontaneous resolution of the lesion and the resultant angular deformity is possible but not entirely predictable. Limb-length discrepancy should be anticipated.
Metal–Organic Frameworks for Removal of Xe and Kr from Nuclear Fuel Reprocessing Plants (2012)

Removal of xenon (Xe) and krypton (Kr) from process off-gases containing 400 ppm Xe, 40 ppm Kr, 78% N(2), 21% O(2), 0.9% Ar, 0.03% CO(2), and so forth using adsorption was demonstrated for the first time. Two well-known metal-organic frameworks (MOFs), HKUST-1 and Ni/DOBDC, which both have unsaturated metal centers but different pore morphologies, were selected as novel adsorbents. Results of an activated carbon were also included for comparison. The Ni/DOBDC has higher Xe/Kr selectivities than those of the activated carbon and the HKUST-1. In addition, results show that the Ni/DOBDC and HKUST-1 can adsorb substantial amounts of Xe and Kr even when they are mixed in air. Moreover, the Ni/DOBDC can successfully separate 400 ppm Xe from 40 ppm Kr and air containing O(2), N(2), and CO(2) with a Xe/Ke selectivity of 7.3 as indicated by our breakthrough results. This shows a promising future for MOFs in radioactive nuclide separations from spent fuels.
The gain equalizing method of erbium doped fiber amplifiers for C-band and L-band (2003)

We realized the excellent gain-flatness of EDFA for wide temperature, wide optical input signal ranges, and changing number of channels using our simply pumping control method. We reported gain constant output signal power in each channel could be obtained by automatic constant pumping power control (APC) for changing conditions (i.e. span loss, number of channels and ambient temperature). In the APC method the configuration is more simple and pumping power is lower compared with AGC method.
Randomized adaptive routing based on mobile agents (2003)

The mobile agent has been shown to be a convenient, efficient, and robust approach to designing distributed protocols. This paper introduces an adaptive, mobile agent-based routing algorithm. While performing a random walk through the network, mobile agents sense changes in the network state, and trigger the computation of updated values for the routing tables. The randomized moving strategy exerts a negligible and balanced impact on the network resources, both in terms of bandwidth and computation. The memory requirement is very moderate. The correctness of the protocol is proven and its complexity is analyzed.
D Electrophoresis of Plant Proteins (2003)

The isolation of proteins from plants for two-dimentional electrophoresis (2-DE) is complicated by the plants’ hard cell walls, high frequency of modified N-termini, and insolubility of membrane proteins. Some of these difficulties are not limited to plant proteins, but are also rather common for proteins from other organisms.
Cost-effective and manufacturable route to the fabrication of high-density 2D micromachined ultrasonic transducer arrays and (CMOS) signal conditioning electronics on the same silicon substrate (2002)

The ability to fabricate Capacitive Micromachined Ultrasonic Transducers (cMUTs) and signal conditioning electronics together on the same silicon substrate offers significant benefits to overall transducer performance, and simplifies connectivity within a dense 2D transducer array. This integration of cMUTs and electronics has been demonstrated utilising a low-temperature silicon nitride membrane technology, post-processed onto CMOS-ASIC substrates. Successful results from fabricated arrays of cMUTs and front-end analogue amplifiers confirm the integration to be relatively simple and highly manufacturable.
Author response: Supramammillary nucleus synchronizes with dentate gyrus to regulate spatial memory retrieval through glutamate release (2020)

Multi-fiber photometry recording and circuit-based manipulation in vivo identify a long-range SuM-DG circuit linking two highly correlated subcortical regions to regulate spatial memory retrieval through SuM glutamate transmission.