gebhart/patrepeval huggingface dataset:
Trichloroethylene Transformation by Natural Mineral Pyrite: The Deciding Role of Oxygen (2008)

The transformation of trichloroethylene (TCE) in natural mineral iron disulfide (pyrite) aqueous suspension under different oxygen conditions was investigated in laboratory batch experiments. TCE transformation was pursued by monitoring its disappearance and products released with time. The effect of oxygen was studied by varying the initial dissolved oxygen concentration (DO(i)) inside each reactor. Transformation rates depended strongly on DO(i) in the system. In anaerobic pyrite suspension, TCE did not transform as it did under aerobic conditions. The transformation rate increased with an increase in DO(i). The TCE transformation kinetics was fitted to a pseudo-first-order reaction with a rate constant k (h(-1)) varying from 0.004 to 0.013 for closed systems with DO(i) varying from 0.017 to 0.268 mmol/L under the experimental conditions. In the aerobic systems, TCE transformed to several organic acids including dichloroacetic acid, glyoxylic acid, oxalic acid, formic acid, and finally to CO2 and chloride ion. Dichloroacetic acid was the only chlorinated intermediate found. Both TCE and the pyrite surface were oxidized in the presence of O2. Oxygen consumption profiles showed O2 was the common oxidant in both TCE and pyrite oxidation reactions. Ferric ion cannot be used as an alternative oxidant to oxygen for TCE transformation.
Enhanced expression of alpha(1,3)-fucosyltransferase genes correlates with E-selectin-mediated adhesion and metastatic potential of human lung adenocarcinoma cells. (1998)

Alpha(1,3)- and alpha(1,4)-fucosylated oligosaccharides such as sialyl-Lewis(x) (sialyl-Le(x)) and sialyl-Lewis(a) (sialyl-Le(a)) have been reported to participate in tumor cell adhesion to activated endothelium. We examined by cytofluorometry the expression of Le(x), sialyl-Le(x), sialyl-Le(x) dimeric, Le(a), and sialyl-Le(a) on the surface of two human lung adenocarcinoma cell lines with different lung colonization potential. High expression levels of all of these antigens were detected in the metastatic HAL-8Luc cells, whereas the closely related nonmetastatic HAL-24Luc cells only expressed the sialyl-Le(a) and sialyl-Le(x) dimeric antigens, both at lower level than in HAL-8Luc cells. Five alpha(1,3)-fucosyltransferases (alpha(1,3)-Fuc-T) controlling the synthesis of these molecules have been identified to date (Fuc-TIII-Fuc-IVII). The expression of these five genes was also higher in the metastatic cells than in the nonmetastatic counterparts as was shown by Northern blot analysis. In vitro adhesion assays showed that only the metastatic cell line adheres significantly to E-selectin-expressing human endothelial cells. Moreover, monoclonal antibody (mAb) blockade of E-selectin completely abolished tumor cell binding. Adhesion inhibition experiments using mAbs against sialylated fucosylated oligosaccharides expressed on tumor cells indicated that these antigens are involved in the binding. Anti-sialyl-Lex(x) mAb (CSLEX-1) inhibited adhesion by 85%; it had the most pronounced inhibitory effect. These findings suggest that the overexpression of alpha(1,3)-Fuc-T genes in the metastatic HAL-8Luc cells, compared with HAL-24Luc cells, results in an enhanced surface display of fucosylated oligosaccharides, which contributes to the adhesive capacity of these cells to the activated endothelium and correlates with their lung colonization potential.
Comparison of self-reported quality of vision outcomes after myopic LASIK with two femtosecond lasers: a prospective, eye-to-eye study (2016)

Creating LASIK flaps with an inverted side-cut using a 150 kHz femtosecond laser and with a conventional 70° side-cut using a 60 kHz femtosecond laser resulted in no significant differences in self-reported QoV assessed by the QoV questionnaire.
Enhanced chemotherapy delivery by intraarterial infusion and blood‐brain barrier disruption in the treatment of cerebral metastasis (2007)

Even with a small number of patients in each subgroup, the results obtained seem promising for multiple brain metastasis of ovarian carcinoma, adenocarcinoma of lung, small cell lung carcinoma, and systemic lymphoma.
Composite Material for Thermochemical Energy Storage Using CaO/Ca(OH)2 (2015)

This work describes a material that has improved mechanical and reactivity properties for use in thermochemical energy storage systems based on CaO/Ca(OH)2 reversible reactions. The composite material uses sodium silicate as a binder of active CaO particles. The observed mechanical stability of the material is due to the formation of hard Ca silicates resulting from the reaction of the binder with the exterior of the CaO particles. A screening of the main synthesis variables affecting the composite was carried out, including Ca precursors of different particle size, a range of molar Ca/Si ratios, as well as the curing and calcination conditions. The most suitable material (containing CaCO3 with a particle size of 36–63 μm as calcium precursor and a molar Ca/Si ratio of 4.8–6.2, calcined in air at 850 °C) was tested over many hydration/dehydration cycles (up to 500) in a thermogravimetric apparatus. The material sustained high molar hydration conversions (between 0.6 and 0.7) and crushing strength values of >2 N after 200 cycles, when dehydrated in pure steam.
Symptoms and signs of an acute myocardial ischemia caused by chemotherapy with Paclitaxel (Taxol) in a patient with metastatic ovarian carcinoma. (2005)

Symptomatic bradyarrhythmia and clinical sign of an myocardial infarction are rare but important cardiac side effects in patients treated with Taxol. Those patients should be under intensive care unit until patients conditions improve and acute myocardial ischemia has been excluded.
Comparison of the Staphylococcal Chromosome Cassette (SCC) mec in Methicillin-Resistant Staphylococcus aureus (MRSA) and Non-aureus Staphylococci (MRNAS) from Animals and Humans (2021)

Methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) and non-<i>aureus</i> staphylococci (MRNAS) cause different infections in animals, including mastitis, in livestock and humans. This study aimed to identify and compare the staphylococcal chromosome cassette <i>mec</i> (SCC<i>mec</i>) types of MRSA or MRNAS isolated from several animal species and humans in different countries. Of 1462 <i>S. aureus</i> and non-<i>aureus</i> staphylococci, 68 grew on Chrom MRSA ID<sup>®</sup> agar, were phenotypically resistant to cefoxitin and tested positive with the PCR for the <i>mecA</i> gene. These 60 MRSA and 8 MRNAS were isolated in Belgium mainly from cows (livestock-associated (LA) MRS) and humans (community-acquired (CA) MRS) and in Japan from dogs and cats. The SCC<i>mec</i> cassettes were identified by multiplex PCR in 52 MRSA and 7 MRNAS and by whole genome sequencing (WGS) in 8 additional MRSA. The SCC<i>mec</i> types IV and V were the most frequent in Belgian LA-MRS and CA-MRS, while the SCC<i>mec</i> type II was identified in four of the five Japanese MRSA. The remaining isolate was a bovine <i>S. haemolyticus</i> in which no SCC<i>mec</i> was identified. These results confirm the high prevalence of the SCC<i>mec</i> types IV and V in LA-MRS and CA-MRS in Belgium, emphasizing the possible public health hazard of the former, and the absence of SCC<i>mec</i> in some MRNAS.
A 10.9GS/s, 64 Taps Distributed Waveform Generator with DAC-Assisted Current-Steering Pulse Generators in 0.18&#956;m Digital CMOS (2008)

A distributed waveform generator (DWG) with DAC-assisted pulse generators is presented for the ultrafast waveform generation. It time-interleaves multiple pulse generators, and uses an on-chip transmission line for wideband pulse combining. Each unit pulse generator adopts a new current-steering topology which incorporates the edge combiner into the conventional current-steering structure for high-speed pulse generation. The transversal structure of the DWG enables a fully reconfigurable waveform generation. A 64-tap, 10.9 GS/S prototype was implemented in 0.18 mum standard digital CMOS technology. The average rise time of basis pulses generated from all 64 taps is 70 ps. The average tap delay is 91.8 ps. Characterization results and some example waveforms are shown in detail.
Simulation des transferts de contamination par les gaz et les aérosols (1981)

On dresse dans cet article le bilan des principales techniques utilisées par le Service de Protection Technique (S.P.T./S.T.E.P.) du C.E.A. dans la simulation des transferts de contamination. Ces techniques permettent d’optimiser les conditions de ventilation des installations nucléaires, elles ont lieu in situ ou sur maquette.
Mixed sensing architecture for 64 Mbit 16-level-cell nonvolatile memories (2002)

This paper presents a sensing architecture for multilevel non-volatile memories. Sensing is carried out following a dichotomic algorithm, where each search step performs a number of parallel comparisons. Two sensing steps are able to detect as many as 16 levels (4 bits) when using three sense amplifiers per cell to be detected. The architecture is suitable for 16 Mcells (64 Mbit) EPROMs, where the memory cells are factory programmed to guarantee the tight threshold voltage distribution required for reliable store and sense.
Multisensor-fusion for 3D full-body human motion capture (2010)

In this work, we present an approach to fuse video with orientation data obtained from extended inertial sensors to improve and stabilize full-body human motion capture. Even though video data is a strong cue for motion analysis, tracking artifacts occur frequently due to ambiguities in the images, rapid motions, occlusions or noise. As a complementary data source, inertial sensors allow for drift-free estimation of limb orientations even under fast motions. However, accurate position information cannot be obtained in continuous operation. Therefore, we propose a hybrid tracker that combines video with a small number of inertial units to compensate for the drawbacks of each sensor type: on the one hand, we obtain drift-free and accurate position information from video data and, on the other hand, we obtain accurate limb orientations and good performance under fast motions from inertial sensors. In several experiments we demonstrate the increased performance and stability of our human motion tracker.
Poly(D,L-lactide-co-glycolide) protein-loaded nanoparticles prepared by the double emulsion method—processing and formulation issues for enhanced entrapment efficiency (2005)

Although extensive research in the field of biodegradable microparticles containing peptide or protein drugs has greatly advanced production know-how, the effects of critical parameters influencing successful drug entrapment have not yet been sufficiently investigated with nano-scaled carriers. This paper deals with the formulation and processing parameters of the w(1)/o/w(2) double emulsion method that can affect nanoparticle size and loading. Fluorescein isothiocyanate-labelled bovine serum albumin (FITC-BSA) was used as a model protein. Results showed that high FITC-BSA entrapment efficiencies were reached (>80%) when sonication was used for the two emulsification steps of the nanoparticle formation, independently of the mixing durations and intensities. By comparison, the use of a vortex mixer for obtaining the primary w(1)/o emulsion led to a rather poor entrapment efficiency (approximately 25%). Some inherent properties of the poly(D,L-lactic-co-glycolic acid) polymer, such as, for example, high molecular weight, high hydrophilicity or the presence of free carboxylic end groups, enhanced the drug entrapment efficiency. It was also demonstrated that a low nominal drug loading, a large volume of the inner w1 phase or the choice of methylene chloride instead of ethyl acetate as organic solvent favoured the drug entrapment, with entrapment efficiency values often reaching 100%. However, when using methylene chloride, the mean particle size was substantially increased, due to the presence of larger particles. Mean particle size increased also when the polymer concentration in the organic phase was increased.
Natural Gaits of the Non-Pathological Flat Foot and High-Arched Foot (2011)

There has been a controversy as to whether or not the non-pathological flat foot and high-arched foot have an effect on human walking activities. The 3D foot scanning system was employed to obtain static footprints from subjects adopting a half-weight-bearing stance. Based upon their footprints, the subjects were divided into two groups: the flat-footed and the high-arched. The plantar pressure measurement system was used to measure and record the subjects' successive natural gaits. Two indices were proposed: distribution of vertical ground reaction force (VGRF) of plantar and the rate of change of footprint areas. Using these two indices to compare the natural gaits of the two subject groups, we found that (1) in stance phase, there is a significant difference (p<0.01) in the distributions of VGRF of plantar; (2) in a stride cycle, there is also a significant difference (p<0.01) in the rate of change of footprint area. Our analysis suggests that when walking, the VGRF of the plantar brings greater muscle tension to the flat-footed while a smaller rate of change of footprint area brings greater stability to the high-arched.
The Cumulative Distribution Function for the Joint Fading and Two Path Shadowing Channel: Expression and Application (2014)

A new expression for the Cumulative Distribution Function (CDF) of the Joint Fading and Two-path Shadowing (JFTS) distribution is derived in this paper. The derived theoretical CDF expression is shown to agree with the experimental results. The CDF expression is used to derive an outage expression for non-diversity transmission which is then used to illustrate the performance of adaptive transmission over the JFTS link.
Analysis of the Photodecomposition Products of Ru(bpy)32+ in Various Buffers and upon Zeolite Encapsulation (2000)

The photodecomposition products of Ru(bpy)3(2+) in water, in aqueous buffered solutions and encapsulated in zeolite-Y have been analyzed by chromatography and UV-visible spectroscopy. The chromatographic method is found to be capable of separating species with the same charge but slightly different ligands as well as geometrical isomers. In all the systems investigated, photodecomposition proceeded via photoaquation resulting in the formation of cis- and trans-Ru(bpy)2(OH2)2(2+). In the case of acetate and phthalate buffers, a third species, Ru(bpy)2(L)(OH2)+, where L is the buffer anion, was found to be the dominant product. For a given pH, the extent of decomposition was found to be dependent on both the buffer anion, following the trend, phosphate < acetate << phthalate and buffer concentration. The presence of the electron-transfer quenching agent, N,N'-dimethyl-4,4'-bipyridinium ion in the medium led to a decrease of the photodecomposition and closely followed the quenching efficiency as measured by intensity and lifetime quenching studies. Encapsulation of Ru(bpy)3(2+) in the supercages of zeolite-Y did not lead to a substantial decrease in photodecomposition as compared to an aqueous solution, suggesting that the expected enhanced stability of Ru(bpy)3(2+*) due to the destabilization of 3dd orbitals and the cage effect was being negated by the close proximity and intrazeolite packing of H2O molecules around the Ru center.
A NEW HEPATO AND RADIOPROTECTIVE AGENT: 2-METHYLPIPERAZINE DITHIOFORMATE (1960)

The pharmacological properties of a series of piperazine dithloderivates were studied and the results obtained with the most active of these derivates, the 2-methylpiperazine dithioformate (DTP), are reported. Characteristics of this substance are a low toxicity, a hepatoprotective action similar to that of methionine, and a radioprotective action comparable to that of cysteamine, against the lesions caused by x-irradiations as well as by radiomimetic agents. (auth)
Supplementary Figure 4 from Complement-Dependent Tumor Cell Lysis Triggered by Combinations of Epidermal Growth Factor Receptor Antibodies (2023)

Supplementary Figure 4 from Complement-Dependent Tumor Cell Lysis Triggered by Combinations of Epidermal Growth Factor Receptor Antibodies
How does clickthrough data reflect retrieval quality? (2008)

Automatically judging the quality of retrieval functions based on observable user behavior holds promise for making retrieval evaluation faster, cheaper, and more user centered. However, the relationship between observable user behavior and retrieval quality is not yet fully understood. We present a sequence of studies investigating this relationship for an operational search engine on the arXiv.org e-print archive. We find that none of the eight absolute usage metrics we explore (e.g., number of clicks, frequency of query reformulations, abandonment) reliably reflect retrieval quality for the sample sizes we consider. However, we find that paired experiment designs adapted from sensory analysis produce accurate and reliable statements about the relative quality of two retrieval functions. In particular, we investigate two paired comparison tests that analyze clickthrough data from an interleaved presentation of ranking pairs, and we find that both give accurate and consistent results. We conclude that both paired comparison tests give substantially more accurate and sensitive evaluation results than absolute usage metrics in our domain.
ON-00364: Selecting Sheep for a Resource Limiting Environment (2017)

In Australia, Merino sheep generally graze and reproduce in extensive grassland systems, characterized by limited feed resources. Under resource limited circumstances, the environment can influence the expression of genes and the health of individuals and constrain ability of individuals and collectives to express genetic progress. Genetic selection has improved productivity of animals represented in the Sheep Genetics database and genetic trends for traits are improving in the stud environment where they are measured. However, on-farm benchmarking data suggests that high index sheep are not necessarily the most profitable when managed in commercial conditions with limited resources. The project was carried out by a multi-disciplinary team that involved physiology, genetics and economics. The project focused on the energy requirements associated with increasing production and the implications of increasing energy requirements in a resource limiting environment. A summary was compiled of the genetic parameters that had been published for the production traits and the traits related to energy (liveweight, body condition score, fat and muscle measurements and intake). Published literature was also reviewed regarding the physiology of increasing CFW and the evidence regarding the energy requirement of increasing CFW. These findings from the physiology review where used in an economic modelling study to quantify the relative economic value of production traits and to identify traits that might be useful to increase profitability in a resource limiting environment. The breeding objectives developed were then compared with the standard MERINOSELECT industry indices. Profit equations were also developed to determine if it was possible to develop an approach to quantifying relative economic values of traits in a resource limiting environment that is more simple than whole farm economic modelling.
Reference-free automatic quality assessment of tracheoesophageal speech (2009)

Evaluation of the quality of tracheoesophageal (TE) speech using machines instead of human experts can enhance the voice rehabilitation process for patients who have undergone total laryngectomy and voice restoration. Towards the goal of devising a reference-free TE speech quality estimation algorithm, we investigate the efficacy of speech signal features that are used in standard telephone-speech quality assessment algorithms, in conjunction with a recently introduced speech modulation spectrum measure. Tests performed on two TE speech databases demonstrate that the modulation spectral measure and a subset of features in the standard ITU-T P.563 algorithm estimate TE speech quality with better correlation (up to 0.9) than previously proposed features.
Effect of cimetidine on the human lower oesophageal sphincter. (1977)

Lower oesophageal sphincter pressures in healthy volunteers were measured by a rapid pull-through technique during intravenous infusion of the histamine H2-receptor antagonist, cimetidine. No consistent effects on sphincter pressure were observed which are liable to be of clinical importance. Serum gastrin concentrations during cimetidine infusion were measured by radioimmunoassay and showed no significant variation. In a further series of experiments, the response of the lower oesophageal sphincter to intravenous bolus injection of pentagastrin was measured before and during cimetidine infusion. Cimetidine infusion had no significant effect on the sphincter response to pentagastrin.
Configuration of systems for testing thermal imagers (2010)

Systems for testing thermal imagers offered commercially are built from the same modules: an off-axis reflective collimator, a motorized rotary wheel, a set of IR targets, a black body, a black body/wheel controller, a PC and some software. The classical solution is that all these components are located horizontally on an optical table. However, it is also possible to use a vertical configuration of the test system when the rotary wheel is put on the collimator and the black body is put on the rotary wheel. It was shown in this paper that when the vertical configuration is used, then better temporal stability and spatial uniformity of the thermal images projected by the test system can be achieved.
Assessment of DNA vaccine potential for juvenile Japanese flounder <i>Paralichthys olivaceus</i>, through the introduction of reporter genes by particle bombardment and histopathology (2002)

The potential for genetic immunization, following DNA particle bombardment for juvenile (4.7cm ±0.3) Japanese flounder Paralichthys olivaceus was examined. Histopathology, at 3 hours post bombardment showed considerable damage to fish epithelial and dermal tissues when bombarded at pressures greater than 200 psi, with many DNA-coated gold particles found to be present. Histopathology, examined at 1, 7, 14 and 28 days post-bombardment showed little pathology at 150 psi with few DNA-coated particles, whereas at 300 psi there was significant pathology observed with many DNA-coated particles seen in conjunction with the cytoplasm of inflammatory cells. Between days 14 and 28 post-bombardment complete epithelial coverage was observed with tissue damage restricted to the dermal layer. CAT assay, following administration of plasmid DNA constructs at 250 psi, showed long term and stable expression of the CAT protein from day 1 to day 60. The transcription activity of two promoters, pCMV-CAT and pSV2-CAT showed marginally greater activity in the former. We conclude that the potential for DNA vaccination of juvenile flounder to be a viable option.
Comprehensive search for intra- and inter-specific sequence polymorphisms among coding envelope genes of retroviral origin found in the human genome: genes and pseudogenes (2005)

Altogether, the present study strongly suggests that some but not all envelope encoding sequences are bona fide genes. It also provides new tools to elucidate the possible role of endogenous envelope proteins as susceptibility factors in a number of pathologies where HERVs have been suspected to be involved.