gebhart/patrepeval huggingface dataset:
Seismic metasurfaces for Love waves control (2018)

Elastic metasurfaces consist of resonant inclusions or resonant oscillators, placed at the free surface of an elastic medium, which collectively interact with surface elastic waves to redirect, steer or absorb their energy. Metasurfaces of vertical oscillators over homogeneous elastic half-spaces can inhibit the propagation of vertical polarized waves (i.e. Rayleigh waves) creating band-gaps at selected frequencies [1]. Such ability has inspired the design of meter-scale metabarriers to protect buildings and infrastructures from harmful seismic Rayleigh waves [2]. In this work, we extend the study of metasurfaces to in-plane polarized surface waves, i.e. Love waves, travelling on a soft elastic layer overlaying a stiffer substrate. We derive an original dispersion relation for the Love type waves existing on a bi-layer coupled on its free surface with a metasurface of horizontal resonators [3]. By tuning the mass and the frequency of the resonators we show the possibility of manipulating the phase velocity of the fundamental Love wave, and thus the related metasurface’s refractive index at specific frequencies.We exploit this ability to design gradient index lenses (i.e. Luneburg and Maxwell lenses) for Love waves redirection. We analyse the performance of the designed lenses using full 3D FE simulations confirming the analytical predictions. Our work can serve as a guide for the design of meter-scale Love waves barriers for seismic or anthropic vibrations attenuation. References [1] N. Boechler, J. K. Eliason, A. Kumar, A. A. Maznev, K. A. Nelson, and N. Fang, Phys. Rev. Lett. 111, (2013). [2] A. Palermo, S. Krödel, A. Marzani, and C. Daraio, Sci. Rep. 6, 39356 (2016). [3] A. Palermo and A. Marzani, submitted to Sci. Rep..
A 3D high-order method for aeroacoustic propagation calculations (2005)

status: Published
1,3-DIMETHYL-5-IMINOTETRAZOLE, A NEW CYCLIC “MESO-IONIC” COMPOUND (1953)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT1,3-DIMETHYL-5-IMINOTETRAZOLE, A NEW CYCLIC "MESO-IONIC" COMPOUNDJohn H. Bryden, Ronald A. Henry, William G. Finnegan, Robert H. Boschan, Wm. S. McEwan, and Robert W. Van DolahCite this: J. Am. Chem. Soc. 1953, 75, 19, 4863–4864Publication Date (Print):October 1, 1953Publication History Published online1 May 2002Published inissue 1 October 1953https://pubs.acs.org/doi/10.1021/ja01115a533https://doi.org/10.1021/ja01115a533research-articleACS PublicationsRequest reuse permissionsArticle Views62Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Poly(allyl glycidyl ether)‐A versatile and functional polyether platform (2011)

Allyl glycidyl ether, polymerized from potassium alkoxide/naphthalenide initiators under both neat and solution conditions was shown to be a highly-controlled process. In both cases, molar masses (10-100 kg/mol) were determined by the reaction stoichiometry, and low polydispersity indices (1.05-1.33) could be obtained with a full understanding of the dominant side reaction, isomerization of the allyl side chain, being developed. The degree of isomerization of allyl to cis-prop-1-enyl ether groups (0 - 10 % mol.) was not correlated to the molar mass or polydispersity of the polymer but was dictated by the polymerization temperature. This allows the extent of isomerization to be reduced to essentially zero under either melt or solution conditions at polymerization temperatures of less than 40 °C.
Sequential cyclic combined hormonal therapy for metastatic breast cancer (1989)

Thirty postmenopausal patients who had evaluable estrogen receptor-positive or unknown metastatic breast cancer were treated with cyclic sequential combined hormonal therapy consisting of 50 micrograms of ethinylestradiol orally daily for 7 days followed by 400 mg of medroxyprogesterone acetate orally daily for 21 days, followed in turn by 7 days of rest. Cyclic administration was continued until progressive disease was detected. Patients who had had one previous chemotherapy regimen were included, but 63% of patients were previously untreated. Six patients achieved complete remission and 11, a partial remission, for an overall response rate of 57%. Median remission duration was 22 months; median time to disease progression for all 30 patients was 8 months. Toxicity consisted of cyclic vaginal bleeding, hot flashes, weight gain, irritability, and fluid retention. This cyclic, sequential hormonal regimen was effective and well tolerated.
Finding text in images via local thresholding (2004)

Texts appearing in images or videos are not only important sources of information but also significant entities for indexing and retrieval purposes. However, since text is often printed against a shaded or textured background it is often difficult to recognize. In this paper, an approach, which can automatically detect, localize and extract horizontally aligned text with different sizes, fonts and languages in images, is presented. The basic idea of our approach is to apply an appropriate local thresholding technique to sequences of line histogram differences in order to increase the robustness of text detection with respect to complex backgrounds. The performance of our approach is demonstrated by presenting experimental results for a set of images taken from video sequences.
The N-acetyl-binding pocket of N-acetylglucosaminyltransferases also accommodates a sugar analog with a chemical handle at C2 (2011)

In recent years, sugars with a unique chemical handle have been used to detect and elucidate the function of glycoconjugates. Such chemical handles have generally been part of an N-acetyl moiety of a sugar. We have previously developed several applications using the single mutant Y289L-β1,4-galactosyltransferase I (Y289L-β4Gal-T1) and the wild-type polypeptide-α-GalNAc-T enzymes with UDP-C2-keto-Gal. Here, we describe for the first time that the GlcNAc-transferring enzymes-R228K-Y289L-β4Gal-T1 mutant enzyme, the wild-type human β1,3-N-acetylglucosaminyltransferase-2 and human Maniac Fringe-can also transfer the GlcNAc analog C2-keto-Glc molecule from UDP-C2-keto-Glc to their respective acceptor substrates. Although the R228K-Y289L-β4Gal-T1 mutant enzyme transfers the donor sugar substrate GlcNAc or its analog C2-keto-Glc only to its natural acceptor substrate, GlcNAc, it does not transfer to its analog C2-keto-Glc. Thus, these observations suggest that the GlcNAc-transferring glycosyltransferases can generally accommodate a chemical handle in the N-acetyl-binding cavity of the donor sugar substrate, but not in the N-acetyl-binding cavity of the acceptor sugar.
Conditions for Copackaging Rous Sarcoma Virus and Murine Leukemia Virus Gag Proteins during Retroviral Budding (1999)

Rous sarcoma virus (RSV) and murine leukemia virus (MLV) are examples of distantly related retroviruses that normally do not encounter one another in nature. Their Gag proteins direct particle assembly at the plasma membrane but possess very little sequence similarity. As expected, coexpression of these two Gag proteins did not result in particles that contain both. However, when the N-terminal membrane-binding domain of each molecule was replaced with that of the Src oncoprotein, which is also targeted to the cytoplasmic face of the plasma membrane, efficient copackaging was observed in genetic complementation and coimmunoprecipitation assays. We hypothesize that the RSV and MLV Gag proteins normally use distinct locations on the plasma membrane for particle assembly but otherwise have assembly domains that are sufficiently similar in function (but not sequence) to allow heterologous interactions when these proteins are redirected to a common membrane location.
Phase calibration for coherent multi-harmonic modulated signal measurements using nonlinear vector network analyzer (2016)

This paper proposes a novel phase calibration approach to enable multi-harmonic modulated signal measurements using existing nonlinear network analyzer (NVNA) receivers configured in wideband mode. The envelopes around the harmonics are captured sequentially so that the dynamic range (DR) of the measurement system is not compromised. A reference signal generated by a comb generator is used to ensure phase coherency between the harmonics, precluding the need to use a small frequency grid that typical solutions require. To validate its ability to make accurate measurements of multi-harmonic modulated signals, the proposed NVNA-based method is tested against a state-of-the-art oscilloscope. The proposed approach is applied first to an 8-tone signal that covers 14 MHz, then on a 5 MHz 1C-WCDMA signal. Both signals have three harmonics with the fundamental frequency at 1 GHz. The phase accuracy of the measured signal is within ±1.5° and ±10° for the first and second test signals, respectively.
Functional Microbes: Technology for Health Foods (2006)

This chapter contains sections titled: Rationale for the Development of GI Tract Targeting Functional Foods Requirements for an Effective Probiotic Health Claims Attributed to Probiotics Mixtures of Pro- and Prebiotics, Synbiotics Probiotic Technology: Maintaining and Enhancing the Functionality and Viability of Microbes with Health Benefits Probiotic Food Market: “Healthy Foods are Here to Stay” References
A formal multi-agent language for cooperative autonomous driving scenarios (2014)

This paper addresses the problem of coordinating autonomous cars to provide higher safety standards in public road traffic with limited computational resources. We present a modelling language that allows formal program verification to guarantee correctness. We apply the multi-agent coordination language ALICA that has originally been developed for the robotic football domain. To show the practical applicability and efficiency for the autonomous driving domain, we applied ALICA to two autonomous car driving scenarios. Thus, we demonstrate the benefits of using a conceptually sound methodology for the coordination of autonomous cars.
ValFold: Program for the aptamer truncation process (2011)

The database is available for free at http://code.google.com/p/valfold/
Spectroscopic study of coal structure and reactivity (1990)

Work done during this period (December 15, 1989 to March 14, 1990) covered two of the three primary areas of study of this project. The first involved the continuing development a of step-scanning interferometer for the photoacoustic depth-profiling of materials whose composition varies in the spatial region between 5 and 50 {mu}m from its surface. The second covered the initial construction of an on-line interface between a supercritical fluid chromatograph (SFC) and a Fourier transform infrared (FT-IR) spectrometer for monitoring the composition of coal extracts. 5 refs., 8 figs.
A 190 GHz Inset-Fed Patch Antenna in SiGe BEOL for On-Chip Integration (2018)

This paper presents the design and characterization of an integrated rectangular patch antenna implemented in the back end of line (BEOL) of a 130 nm silicon germanium (SiGe) technology. The inset-fed antenna has a patch area of 0.19 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . To the knowledge of the authors, this is one of the smallest radiating element areas reported in literature for on-chip antennas at comparable frequencies. Electromagnetic simulations show a maximum antenna gain of 2.6 dBi and a directivity of 9.3 dBi. The measured resonance frequency of 192.3 GHz is in agreement with post-layout simulation results. Design challenges including impact of density fillers in integrated technologies are also discussed.
Optimal design of DC fast-charging stations for EVs in low voltage grids (2017)

DC Fast Charging Station (DCFCS) is essential for widespread use of Electric Vehicle (EVs). It can recharge EVs in direct current in a short period of time. In recent years, the increasing penetration of EVs and their charging systems are going through a series of changes. This paper addresses the design of a new DCFCS for EVs coupled with a local Battery Energy Storage (BES). DCFCS is equipped with a bidirectional AC/DC converter for feeding power back to the grid, two lithium batteries and a DC/DC converter. This paper proposes an optimal size of the BES to reduce the negative impacts on the power grid through the application of electrical storage systems within the DC fast charging stations. The proposed solution decreases the charging time and the impact on the low voltage (LV) grid significantly. The charger can be used as a multifunctional grid-utility such as congestion management and load levelling. Finally, an optimal design of the DCFSC has been done to evaluate the feasibility and the operability of the system in different EVs load conditions.
Fluorescence detection system using a krypton laser: application to cancer diagnosis in photodynamic therapy (1995)

The hematoporphyrin derivative (HpD) is one of the most employed fluorescent markers for cancer diagnosis due to its ability to localize itself at a higher level in most tumor tissues and to emit a characteristic red fluorescence upon excitation with light at proper wavelength. This autofluorescence is responsible for a significant decrease of the fluorescence contrast between the tumor and the surrounding normal tissue. Consequently, there is a need to develop techniques to detect this fluorescence. This paper deals with the conception of a diagnosis system to detect early cancer at the surface of the hollow organs in the human body by endoscopy. The device and the principle of the image processing are detailed, and the limits of this system are discussed through the analysis of measurements carried out on phantoms and nude mice.
IFNα and 5-Aza-2’-deoxycytidine combined with a dendritic-cell targeting DNA vaccine alter tumor immune cell infiltration in the B16F10 melanoma model (2023)

Efficient targeting of antigen to immature DCs with a chemokine-fusion vaccine offers a potential alternative approach to classic and dendritic cell-based vaccines. Combining this approach with IFNα and 5Aza treatments significantly improved vaccine efficacy. This treatment creates an environment of increased inflammatory chemokines that facilitates the trafficking of CD8+ DCs, NK cells, and CD8+ T-cells, especially memory cells, while reducing the number of MDSCs. Importantly, in the combination group, CD8+ cells were more able to penetrate the tumor mass in addition to being more numerous. Further analysis of the pathways engaged by our combination therapy is expected to provide additional insights into melanoma pathogenesis and facilitate the development of novel treatment strategies.
Immuno‐Carbon Nanotubes and Recognition of Pathogens (2005)

Tubular warning bells. Water-soluble, protein-functionalized, single-walled carbon nanotubes (immuno-SWNTs) have been prepared that can recognize and capture pathogenic E. coli cells selectively by antibody–antigen conjugation in a physiological environment, as shown in the scanning electron microscopy image.
Wave Overtopping and Damage Progression of Stone Armor Layer (2010)

A probabilistic hydrodynamic model for the wet and dry zone on a permeable structure is developed to predict irregular wave action on the structure above the still water level. The model is based on the time-averaged continuity and momentum equations for nonlinear shallow-water waves coupled with the exponential probability distribution of the water depth. The model predicts the cross-shore variations of the mean and standard deviation of the water depth and horizontal velocity. The model is compared with four test series in which measurement was made of the wave overtopping rate and probability as well as the water depth, velocity, and discharge exceeded by 2% of incident 1,000 waves. The agreement is mostly within a factor of 2. Damage progression of a stone armor layer is predicted by modifying a formula for bed load on beaches with input from the hydrodynamic model. The damage progression model is compared with three tests that lasted up to 28.5 h. The model predicts the eroded area of the damaged armor layer well but overpredicts the deposited area because it does not account for discrete stone units deposited at a distance seaward of the toe of the damaged armor layer.
Abstract TP468: Differential Effect of Ischemia and Thrombin Mediated Toxicity on Neurovascular Unit (2020)

Objectives: Brain is a complex structure during ischemia along with neurons; components of vascular unit astrocytes, pericytes and endothelial cells play a major role in hypoxic and blood brain barrier leakage mediated injury. Thrombin acts via protease activated receptor-1 (PAR-1) and leads to neuronal survival or death, PAR-1 knockout cells survive ischemia. We hypothesize that different elements of the Brain vascular unit play different roles in responding to injury. The present study aimed to establish a correlation between astrocytes, pericytes and endothelial cells vulnerability via OGD model of ischemia and Thrombin mediated toxicity. Methods: Using highly reproducible oxygen glucose deprivation (OGD) model Primary cultured cells were exposed to OGD for various durations and Thombin doses to determine the optimum time point for 80 % cell death or cell viability measured using LDH release assay MTT assay. LD50 dose of OGD and Thrombin was used to determine the effect of various drugs mediating PAR-1 receptor pathway Results: The viability assay using MTT showed that the three elements of vascular unit respond differentially to longer durations of ischemia, with pericytes being the most vulnerable, followed by endothelial cells, followed by astrocytes. Our thrombin dose effect shows that Pericytes and endothelial respond to thrombin similarly whereas, astrocytes on lower concentration proliferate, but don’t survive the higher concentrations. Conclusion: An exciting, novel finding in our data is that different elements of the vascular unit—astrocytes, pericytes and endothelial cells—all exhibit effect of ischemia and reperfusion at different time scales. Up until recently, studies of neuroprotection addressed the brain as a homogenous unit, with the tacit assumption that all elements responded similarly. Our data on astrocytes, endothelial cells and pericytes—allows more focused investigation.
PASSIVE EQUALIZATION OF NON-UNIFORM EDFA GAIN BY OPTICAL FILTERING FOR MEGAMETER TRANSMISSION OF 20 WDM CHANNELS THROUGH A CASCADE OF EDFA's (1993)

Erbium-doped fiber amplifiers (EDFA's) have revolutionized both long-distance and distribution-based optical communication systems. Adequate signal-to-noise ratios (SNR) have already been demonstrated for both single-channel [1] and two-wavelength-channel [2] multi-megameter transmission systems as well as for wavelength-division-multiplexed (WDM) distribution systems.[3-5] However, transmitting many WDM amplified channels is difficult to implement since the EDFA gain as a function of wavelength is not uniform whereas the link loss (due to propagation attenuation or optical splitting) is independent of wavelength. Such a gain/loss wavelength discrepancy will result in a signal-power and SNR differential between channels after passing through only one amplifier for either long-distance or distribution systems. As a result of passing through a cascade of EDFA's, this discrepancy is compounded.
Metalloligand Strategies for Assembling Heteronuclear Nanocages – Recent Developments* (2019)

The use of metalloligands as building blocks for the assembly of metallo-organic cages has received increasing attention over the past two decades or so. In part, the popularity of this approach reflects its stepwise nature that lends itself to the predesigned construction of metallocages and especially heteronuclear metallocages. The focus of the present discussion is on the use of metalloligands for the construction of discrete polyhedral cages, very often incorporating heterometal ions as structural elements. The metalloligand approach uses metal-bound multifunctional ligand building blocks that display predesigned structural properties for coordination to a second metal ion such that the rational design and construction of both homo- and heteronuclear metal–organic cages are facilitated. The present review covers published literature in the area from early 2015 to early 2019.
ChemInform Abstract: Catalytic, Asymmetric, and Stereodivergent Synthesis of Non‐symmetric β,β‐Diaryl‐α‐Amino Acids. (2015)

Abstract Stereodefined enol tosylates such as (III) and (VI) are prepared and subjected to a stereoretentive Suzuki—Miyaura coupling.
Brunel Inverse DGPS Positioning System (2001)

ABSTRACT: This paper presents an inverse differential GPS (DGPS) system that has been established at Brunel University. This system can be employed for applications requiring the user's location with improved DGPS accuracy, which is achieved by computing the remote receiver's position at the base station rather than at the remote site. In this system, the correction data are not transmitted from the base station, but the positioning data from the remote receiver are sent to the base station, where the DGPS position is calculated. This approach is especially relevant in applications where a remote unit reports its location to the service center: A typical scenario may be emergency location service, when the location of an emergency caller needs to be reported to a dispatch center.
Autonomous wearable RFID-based sensing platform for the Internet-of-Things (2017)

An autonomous wearable radio-frequency identification (RFID) tag with sensing, processing, and decision-taking capability is presented for operation in the 2.45-GHz RFID band. The tag relies on a dedicated textile shorted circular patch antenna with tailored radiation pattern for operation in a smart floor/ceiling environment. By means of an holistic design strategy, the textile antenna's functionality is augmented by reusing its surface as an integration platform for sensing, computing, transceiver, and light-energy-harvesting hardware. Special attention was paid to align the tag's power consumption profile with the power generation profile of the energy harvester. Measurements under free-space conditions and in a realistic indoor scenario demonstrate excellent wearability, very high read range, enhanced functionality, and extended system autonomy.