gebhart/patrepeval huggingface dataset:
Sirpent: a high-performance internetworking approach (1989)

A clear target for computer communication technology is to support a high-performance global internetwork. Current internetworking approaches use either concatenated virtual circuits, as in X.75, or a “universal” internetwork datagram, as in the DoD Internet IP protocol and the ISO connectionless network protocol (CLNP). Both approaches have significant disadvantages.This paper describes Sirpent™ (Source Internetwork Routing Protocol with Extended Network Transfer)1, a new approach to an internetwork architecture that makes source routing the basis for interconnection, rather than an option as in IP. Its benefits include simple switching with low per-packet processing and delay, support for accounting and congestion control, and scalability to a global internetwork. It also supports flexible, user-controlled routing such as required for security, policy-based routing and realtime applications. We also propose a specific internetwork protocol, called VIPER™2, as a realization of the Sirpent approach.
Increasing Coke Impurities – Is this Really a Problem for Metal Quality? (2012)

This chapter contains sections titled: Introduction Anode Grade Calcined Coke Challenges Impacts at Smelter for Higher Impurities Studies on the Higher Impurity Levels on Aluminium Properties A Pathway Forward for the Industry
Genetic algorithm based resource allocation and interference mitigation for OFDMA macrocell-femtocells networks (2013)

In this paper, we propose a base station selection and resource allocation model for OFDMA macro-femtocell networks. Dense deployment of femtocells can cause severe interference for femto and macro users alike. Our framework assumes hybrid-access femtocells to grant access to public user in their vicinity and to reduce interference perceived by femto users. Full spectrum sharing is investigated for the purpose of increasing system capacity. The proposed model aims to maximize the network throughput for a given interference threshold. To do so, the model determines the best serving base station based on link conditions. Genetic Algorithm is used to solve the resource optimization problem by finding the appropriate bandwidth and power assignments for each user. Simulations were conducted and a comparison with a modified version of the Weighted Water Filling algorithm is presented.
Research on detection method of electromagnetic ultrasonic signal based on FPGA (2008)

The transduction efficiency of an electromagnetic acoustic transducer (EMAT) is rather low, while the receiving coil of the transducer is very sensitive to the environment noise, which leads to a low signal-to-noise ratio (SNR) of the received signal. Consequently, the receiving circuit of an EMAT detection system must have a strong ability of weak signal detection under a noisy environment. To improve the SNR of the received signal and to efficiently extract echoes reflected by defects, we propose a detecting method combining wavelet transform and FIR filter. Feasibility and efficiency of the method is verified by experiments. The proposed algorithm is realized by FPGA, which can significantly improve the detecting efficiency, and reduce the volume as well as the cost of the detection system.
Fusion of luxA and luxB and its expression in E. coli, S. cerevisiae and D. melanogaster (1990)

Luciferase from Vibrio harveyi is encoded by two adjacent genes, luxA and luxB. The two genes were fused by replacing a segment extending from near the end of luxA into the N-terminal end of luxB by a synthetic oligonucleotide. The construction removed the TAA stop codon at the end of luxA, the intervening region of 26 base pairs, and the initial methionine of luxB. A Smal site was included at the junction between the two genes and an AatII site was created near the end of luxA without altering its amino acid sequence. In Escherichia coli the fused luxAB gene could be expressed to produce functional luciferase that gave about 20% of the activity in cells without the fusion. An out-of-frame ATG exists close to and preceding the ATG of the luxA gene. This was removed and the entire fused gene bracketed by several restriction enzyme sites. The fused luxAB gene was successfully expressed in Saccharomyces cerevisiae and Drosophila melanogaster by transferring it to appropriate plasmid vectors.
Analysis on higher education scientific and technological innovation based on panel data (2009)

We illustrated the status of each Province's higher education scientific and technological(S&T) innovation in China, and then aimed on this status, established panel data model to analyze the capability of these Provinces' higher education S&T innovation. According to the established panel data model, we got the conclusion that the overall level of Chinese higher education S&T innovation consciousness is not high, and funds input could translate into S&T innovation output more effectively than human input.
The Annexin II-p11 Complex Is Involved in Regulated Exocytosis in Bovine Pulmonary Artery Endothelial Cells (1998)

Annexin II is a member of a multigene family of Ca2+-regulated, membrane-binding proteins implicated through biochemical and perforated cell experiments in Ca2+-triggered secretion. Within most cells annexin II resides in a tight heterotetrameric complex with a cellular protein ligand, p11, and complex formation is mediated via the N-terminal 14 residues of annexin II including the N-terminal acetyl group. To analyze at the single cell level whether the annexin II-p11 complex is involved in regulated secretion, we used membrane capacitance measurements to follow exocytotic fusion events in bovine aortic endothelial cells manipulated with respect to their annexin II-p11 complex formation. Upon guanosine 5'-O-(thiotriphosphate) (GTPgammaS) stimulation, the endothelial cells show a significant increase in membrane capacitance which is generally preceded by a transient rise in intracellular Ca2+ and thus indicative of the occurrence of Ca2+-regulated secretion. The GTPgammaS-induced capacitance increase is markedly reduced in cells loaded with a synthetic peptide, Ac1-14, which corresponds in sequence to the N-terminal 14 residues of annexin II in their correctly acetylated form and which is capable of disrupting preformed annexin II-p11 complexes. The effect of the peptide is highly specific as the nonacetylated variant, N1-14, which is incapable of disrupting annexin II-p11, does not interfere with the GTPgammaS-induced increase in membrane capacitance. These data show that intact annexin II-p11 complexes are indispensable for regulated exocytosis to occur in an efficient manner in endothelial cells.
Incidence of Hematologie Disease in Patients with Carpal Tunnel Syndrome (1962)

MEDIAN NEURITIS resulting from compression in the carpal tunnel may occur in a variety of otherwise unrelated illnesses. Frequently, no specific primary cause is found, although any disease or condition that increases the contents in the carpal canal may result in compression of the nerve against the transverse carpal ligament. Thus, tenosynovitis or edema of the tenosynovium from any cause, may produce secondary compression of the nerve. The symptom complex resulting from this compression, commonly known as the carpal tunnel syndrome, consists of unilateral or bilateral episodic paresthesias, involving part or all of the distribution of the median nerve in the hand. These are intensified several hours after retirement, and nocturnal pain is a feature. The pain may awaken the patient from sleep, and often is relieved by shaking the extremity or maintaining it in a dependent position. Symptoms decrease with morning activities, although they may be aggravated by overexertion.
Molecular Regulation of Sprouting Angiogenesis (2017)

The term angiogenesis arose in the 18th century. Several studies over the next 100 years laid the groundwork for initial studies performed by the Folkman laboratory, which were at first met with some opposition. Once overcome, the angiogenesis field has flourished due to studies on tumor angiogenesis and various developmental models that can be genetically manipulated, including mice and zebrafish. In addition, new discoveries have been aided by the ability to isolate primary endothelial cells, which has allowed dissection of various steps within angiogenesis. This review will summarize the molecular events that control angiogenesis downstream of biochemical factors such as growth factors, cytokines, chemokines, hypoxia-inducible factors (HIFs), and lipids. These and other stimuli have been linked to regulation of junctional molecules and cell surface receptors. In addition, the contribution of cytoskeletal elements and regulatory proteins has revealed an intricate role for mobilization of actin, microtubules, and intermediate filaments in response to cues that activate the endothelium. Activating stimuli also affect various focal adhesion proteins, scaffold proteins, intracellular kinases, and second messengers. Finally, metalloproteinases, which facilitate matrix degradation and the formation of new blood vessels, are discussed, along with our knowledge of crosstalk between the various subclasses of these molecules throughout the text. Compr Physiol 8:153-235, 2018.
Terrorism (Un) Veiled: Frantz Fanon and the Women of Algiers (1990)

She was therefore enveloped in veils and flowing robes like explosive material which has to be well packed. In some Arab societies, this uncovering of a finger or a toe was considered a potential source of fitna [i.e., chaos motivated by feminine seductiveness] in society which might therefore lead to anarchy, uprisings, rebellions and the total destruction of the established order! -Nawal El Saadawi
FAILURE OF CEFTRIAXONE THERAPY TO ERADICATE SALMONELLA ENTERITIDIS FROM THE GASTROINTESTINAL TRACT OF NEONATES (1987)

1Edward Mallinckrodt Department of Pediatrics Washington University School of Medicine 2The Division of Infectious Diseases St. Louis Children's Hospital St. Louis, MO Accepted for publication Aug. 3, 1987. Address for reprints: Dan M. Granoff, M.D., Division of Infectious Diseases, Children's Hospital, 400 S. Kingshighway, St. Louis, MO 63110.
High power monolithically integrated all-fiber laser design using single-chip multimode pumps for high reliability operation (2008)

We present an all-fiber monolithically integrated fiber laser based on a custom tapered fused bundle pump combiner with 32 inputs ports connected to a double clad gain fiber. The pump combiner is designed to provide high isolation between signal and pumps fibers providing intrinsic pump protection. This configuration can generate more than 100W of continuous wave (CW) laser light using single-chip multimode pumps enabling long term reliability.
FPGA-based simulation of 3D light propagation (2014)

In this paper, we describe how to emulate 3D wave dynamics on a 2D FPGA-based architecture. The algorithm is based on the Paraxial Helmholtz Equation: which describes the beam propagation through different media with different refractive indices. To solve this wave propagation equation numerically the FPGA-accelerated hardware operates with spatially varying templates. The FPGA-based wave-equation solver is very well parallelizable, so the resulting algorithm will also be amenable to mega-core architectures.
Arbeidsvoorwaarden van vaste en tijdelijke werknemers (2001)

sponsorship: Onderzoeksgroep Personeel en organisatie.
Work as Meaning: Individual and Organizational Benefits of Engaging in Meaningful Work (2009)

We review the literature on work as meaning and propose a theoretical model of factors that support engagement in meaningful work. We argue that meaningful work arises when people have a clear sense of self, an accurate understanding of the nature and expectations of their work environment, and understand how to transact with their organizations to accomplish their work objectives. We argue that this comprehension of the self in work provides the foundation for people to develop a sense of purpose and mission about their work that both motivates their engagement and performance and helps them transcend their own immediate interests to achieve concern for their contributions to their organization and the greater good. We describe potential and documented benefits of meaningful work to individuals and organizations and provide some suggestions for practical applications and future research.
Clinical Presentation and Prognostic Factors in Sodium Monofluoroacetate Intoxication (1996)

Hypotension and the early onset of metabolic acidosis and increased serum creatinine are associated with poor short-term survival. These prognostic variables can be useful in the care of patients with suspected sodium monofluoroacetate intoxication. It is suggested that all such patients should be observed intensively for at least 48 h.
Plant Transformation (2010)

Abstract The genetic constitution of plants can be altered in the laboratory by a process called transformation, whereby a segment of DNA ( deoxyribonucleic acid ) is introduced that becomes inserted in one of the plant chromosomes. Several methods to accomplish plant transformation have been devised. In all these methods, single cells are transformed and thereafter regenerated into complete, fertile plants by tissue culture procedures. Some of the transformation methods can only be applied to protoplasts (cells from which the walls have been removed). Nowadays, particle bombardment and the natural vector Agrobacterium tumefaciens are preferred because they can also cope with whole plant tissues such as roots and leaves, which are easier to handle, more stable and require less of the lengthy steps that are required for plant regeneration. Transgenes are integrated at random positions in the plant genome, but procedures for targeted integration become more and more efficient. Key concepts: Transgenic plants are plants derived from cells in which genes (often of nonplant origin) have been stably introduced by transformation to give the plant a new and useful trait. Transgenic plants can be obtained after transformation of single cells and the subsequent regeneration into complete, fertile plants by tissue culture protocols. Transformed plant cells can be identified by their ability to grow on selective media containing an antibiotic or a herbicide as transformation vectors contain selection genes conferring such properties. Novel functions are expressed in transformed plant cells if the coding regions are surrounded by promoter and terminator regions that are recognized by the plant transcription machinery. The most preferred methods for plant transformation use either the particle gun or the natural transformation system of Agrobacterium tumefaciens , as they can cope with cells present in whole plants or tissues. Agrobacterium tumefaciens can be disarmed by deletion of the onc ‐genes that are naturally present between the 25‐bp repeats of the T‐DNA. Any gene introduced between these repeats is translocated into plant cells by Agrobacterium tumefaciens. Transformed cells with a single copy of the transgene usually show higher and more stable expression than multicopy lines, in which expression may suffer from posttranscriptional gene silencing. (T)‐DNA integration in plant cells occurs at random sites in the genome by nonhomologous end‐joining and related backup pathways. Targeted integration of transgenes can be accomplished in plant cells by using either a site‐specific recombination system (e.g. Cre‐ lox ) or by homology‐directed integration in combination with a site‐specific nuclease (e.g. a zinc‐finger nuclease). Agrobacterium tumefaciens ‐mediated transformation can be applied not only in dicotyledonous plants, but also in monocots such as cereals and in yeasts and fungi. The T‐DNA can be used as a mutagen causing insertion mutations. Libraries of Arabidopsis thaliana T‐DNA transformants are in use now in mutant screens to identify insertion mutations in genes of interest (reverse genetics).
Receptors involved in helodermin action on rat pancreatic acini (1986)

Helodermin is a new peptide isolated from the venom of Heloderma suspectum. Its effects on rat pancreatic acini were compared with those of secretin and vasoactive intestinal peptide (VIP). Four classes of receptors with decreasing affinity for secretin (S1, S2, S3, and S4) were first delineated. Occupancy of S1 and S2 by secretin was responsible for a biphasic adenosine 3',5'-cyclic monophosphate (cAMP) response. S3 was VIP preferring so that the VIP-induced increase in cAMP could be inhibited by VIP-(10-28). S2 and S3 allowed cAMP elevation, protein phosphorylation, weak secretory effects, and potentiation of cholecystokinin octapeptide (CCK-8) when occupied by secretin and VIP, respectively. A more efficient exocytosis was observed with secretin interacting with low-affinity receptors S4. Helodermin increased cAMP levels 14-fold, this increase being inhibited by VIP-(10-28). Low concentrations of helodermin stimulated amylase secretion twofold and potentiated secretion by CCK-8. High concentrations of helodermin stimulated secretion another 2.6-fold. Helodermin bound to the four secretin receptors with a weak selectivity. At low concentration, helodermin stimulated cAMP elevation, protein phosphorylation, amylase release, and potentiation of CCK-8 through S3, whereas at high concentration it stimulated secretion via S4.
The synthesis and study of the photoinitiated cationic polymerization of novel cycloaliphatic epoxides (1995)

Abstract The synthesis of a series of difunctional epoxides bearing two epoxycyclohexyl groups linked together by an alkylene ether group has been carried out. Subsequently, the reactivities of these novel monomers was investigated and compared to the reactivity of the cycloali‐phatic epoxide, 3,4‐epoxycyclohexylmethyl 3′,4′‐epoxycyclohexane carboxylate ( I ) in pho‐toinitiated cationic polymerization. It was observed that alkylene oxide linking the two epoxycyclohexyl groups was short and the monomers are more reactive than I . The effects of the photoinitiator structure and the experimental conditions of the cationic photopo‐lymerization on the rates was also studied using real‐time infrared spectroscopy. © 1995 John Wiley &amp; Sons, Inc.
Channel adaptive multiple I/O protocol for mixed wireless and wired channels (2007)

The presence and availability of several independent wired and wireless networks within a communication environment has led to the channel adaptive multiple I/O (CAMIO) protocol being developed as an appropriate and novel technique for data transmission. The proposed system utilises an intelligent multiplexing technique that enables the transmission/reception of multiple data sources via several wired/wireless networks simultaneously. Real-time configuration and adaptation capabilities when data sources/channels are dynamically added/deleted/modified are described. Data prioritisation methods, combined with traffic control and congestion-reactive techniques, are presented. Simulation results demonstrate that the use of the CAMIO protocol over multiple transmission/reception channels increases the overall data transmission rate, handles the delivery of time-sensitive packets and maintains the quality of service, especially in situations where one or more communication channels fail to operate.
Regulation of insulin-like growth factor-binding proteins in the baboon (Papio anubis) uterus during early pregnancy. (1992)

The baboon uterus begins to synthesize insulin-like growth factor-binding protein-1 (IGFBP-1) in the deep glands of the late secretory endometrium, and this protein then becomes the major secretory product of the term decidua. We hypothesized that the placenta and/or conceptus may regulate the synthesis and secretion of IGFBP-1 by decidualized stromal cells during pregnancy. To test this hypothesis, tissue was obtained from pregnant baboons on days 18, 25, and 32 postovulation. The uterus was separated into three regions: RI (directly below the implantation site), RII (adjacent to the implantation site), and RIII (opposite the implantation site). Portions of the tissue were fixed in Bouin's solution for immunocytochemistry, and the remainder was subdivided into functionalis, basalis, and myometrium and subjected to organ explant culture. The placenta was fixed or cultured separately. Ligand blot analysis of functionalis medium showed that the major IGFBP had a mol wt (Mr) of 29,000-31,000; however, a doublet of 37,000-43,000 Mr and a band at 24,000 Mr were also present. The functionalis from all regions expressed the majority of the IGFBPs, but basalis from RI tissue also secreted the same array of IGFBPs on days 25 and 32. Ligand blot analysis of placental medium proteins revealed a doublet at Mr 37,000-43,000 on days 25 and 32, but not on day 18. Immunoprecipitation followed by ligand blot analysis of medium proteins using polyclonal antibodies to IGFBP-1 and IGFBP-2 and -3 confirmed that IGFBP-1 and -2 were the predominant products of the endometrium and decidua, while IGFBP-3 was synthesized by the placenta. Immunocytochemistry with a monoclonal antibody to IGFBP-1 demonstrated intense glandular epithelial staining in all regions on days 18, 25, and 32. Stromal staining for IGFBP-1 was first evident on day 25 and was only present in stromal cells in intimate contact with the trophoblastic tissue. By day 32, IGFBP-1 expression was not limited to the endometrial-trophoblastic junction, but extended to the deeper stromal cells and included the perivascular regions. IGFBP-1 staining was most intense in RI, but stromal cells at the luminal surface and those surrounding the spiral arteries also showed some staining in RII and RIII on day 32. These studies suggest that the baboon placenta and/or conceptus regulate IGFBP expression in the uterine endometrium during the initial stages of pregnancy.(ABSTRACT TRUNCATED AT 400 WORDS)
Sound parameters for expressing geographic distance in a mobile navigation application (2011)

This paper presents work on finding acoustic parameters suitable to convey a sense of difference in geographic distance through the concepts of "near", "middle" and "far". The context for use is a mobile application for navigation services. A set of acoustic parameters was selected based on how sound naturally travels through and is dispersed by the atmosphere. One parameter without direct acoustic connection to distance was also selected. Previous works corroborate the choice of parameters in the context of the project. Results show that modulating multiple parameters simultaneously to express distance gives a more robust experience of difference in distance compared to modulating single parameters. The ecological parameters low-pass filter and reverb gave the test's subjects the most reliable and consistent experience of difference in distance. Modulating the parameter pitch alone was seen to be an unreliable method. Combining the pitch parameter with the reverb parameter gave more robust results.
Supplementary Data from Isogenic Normal Basal and Luminal Mammary Epithelial Isolated by a Novel Method Show a Differential Response to Ionizing Radiation (2023)

Supplementary Data from Isogenic Normal Basal and Luminal Mammary Epithelial Isolated by a Novel Method Show a Differential Response to Ionizing Radiation