gebhart/patrepeval huggingface dataset:
2H22 Fabrication and evaluation of β-TCP/PLLA scaffold with good osteoconductivity and handleability (2016)

In the field of bone regenerative medicine, the need for artificial bone substitutes has been rapidly increasing, and various porous bioactive ceramics have been developed for use as bone substitutes. While materials such as β-tricalcium phosphate (β-TCP) have good oseteoconductivity, poly (L-lactide acid) (PLLA) has been shown to have good mechanical and physical properties. Therefore, the primary aim of this study was to fabricate a porous β-TCP scaffold with a PLLA network structure (β-TCP/PLLA) for use in bone tissue engineering. The fabricated β-TCP/PLLA scaffolds were characterized by their surface micro structures and compressive moduli. The results demonstrated that the structure of the PLLA membrane, such as pore size and thickness of membrane, could be changed by varying the concentration of PLLA.
SARS-CoV-2-Specific T Cell Responses Are Stronger in Children With Multisystem Inflammatory Syndrome Compared to Children With Uncomplicated SARS-CoV-2 Infection (2022)

Age-related differences in the magnitude of CST responses suggest differing post-infectious immunity to SARS-CoV-2 in children compared to adults post uncomplicated infection. Children with MIS-C have CST responses that are stronger than children with uncomplicated SARS-CoV-2 infection and weaker than convalescent adults, despite near uniform seropositivity.
Association of the HLA antigens with early atheromatosis in subjects with type 2 diabetes mellitus. (2002)

Human leukocyte antigen A3 is associated with less vascular damage, as expressed by carotid wall thickness, in subjects with type 2 DM. These subjects may be characterized by a milder inflammatory response, as shown by the lower serum levels of CRP.
Topology Identification in Distribution Systems Using Line Current Sensors: An MILP Approach (2019)

This study is motivated by the recent advancements in developing non-contact line sensor technologies that come at a low cost, but have limited measurement capabilities. While they are intended to measure current, they cannot measure voltage and power. This poses a challenge to certain distribution system applications, such as topology identification (TI), because they commonly use voltage and power measurements. To address this open problem, a new TI algorithm is proposed based on measurements from a few line current sensors, together with available pseudo-measurements for nodal power injections. A TI problem formulation is first developed in the form of a mixed integer nonlinear program (MINLP). Several reformulation steps are then adopted to tackle the nonlinearities to express the TI problem in the form of a mixed integer linear program (MILP). The proposed method is able to identify all possible topologies, including radial, loop, and island configurations, which extends the application of TI to identify switch malfunctions and to detect outages. In addition, recommendations are made with respect to the number and location of the line current sensors to ensure performance accuracy of the TI method. A novel multi-period TI algorithm is also proposed to use multiple measurement snapshots to improve the TI accuracy and robustness against errors in pseudo-measurements. The effectiveness of the proposed TI algorithms is examined on the IEEE 33-bus test case as well as a test case based on a real-world feeder in Riverside, CA.
Photogrammetry and Videogrammetry Methods Development for Solar Sail Structures (2003)

This report discusses the development and application of metrology methods called photogrammetry and videogrammetry that make accurate measurements from photographs. These methods have been adapted for the static and dynamic characterization of gossamer structures, as four specific solar sail applications demonstrate. The applications prove that high-resolution, full-field, non-contact static measurements of solar sails using dot projection photogrammetry are possible as well as full-field, non-contact, dynamic characterization using dot projection videogrammetry. The accuracy of the measurement of the resonant frequencies and operating deflection shapes that were extracted surpassed expectations. While other non-contact measurement methods exist, they are not full-field and require significantly more time to take data.
Polyamide‐imide nanofiltration hollow fiber membranes with elongation‐induced nano‐pore evolution (2009)

Abstract The molecular design of nanoporous membranes with desired morphology and selectivity has attracted significant interest over the past few decades. A major problem in their applications is the trade‐off between sieving property and permeability. Here, we report the discovery of elongation‐induced nano‐pore evolution during the external stretching of a novel polyamide‐imide nanofiltration hollow fiber membrane in a dry‐jet wet‐spinning process that simultaneously leads to a decreased pore size but increased pure water permeability. The molecular weight cutoff, pore size, and pore size distribution were finely tuned using this approach. AFM and polarized FTIR verified the nano‐pore morphological evolution and an enhanced molecular orientation in the surface skin layer. The resultant nanofiltration membranes exhibit highly effective fractionation of the monovalent and divalent ions of NaCl/Na 2 SO 4 binary salt solutions. More than 99.5% glutathione can be rejected by the nanofiltration membranes at neutral pH, offering the feasibility of recovering this tripeptide. © 2009 American Institute of Chemical Engineers AIChE J, 2010
Molecular Optoelectronic Gates (1996)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTMolecular Optoelectronic GatesRichard W. Wagner, Jonathan S. Lindsey, Jyoti Seth, Vaithianathan Palaniappan, and David F. BocianView Author Information Department of Chemistry Carnegie Mellon University, 4400 Fifth Avenue Pittsburgh, Pennsylvania 15213-2683 Department of Chemistry, University of California Riverside, California 92521-0403 Cite this: J. Am. Chem. Soc. 1996, 118, 16, 3996–3997Publication Date (Web):April 24, 1996Publication History Received25 January 1996Published online24 April 1996Published inissue 24 April 1996https://doi.org/10.1021/ja9602657Copyright © 1996 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views1369Altmetric-Citations277LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (75 KB) Get e-AlertsSUBJECTS:Dyes and pigments,Fluorescence,Oxidation,Pyrroles,Redox reactions Get e-Alerts
Selective BOLD responses to individual finger movement measured with fMRI at 3T (2011)

Although the gross somatotopic organization of the posterior bank of the precentral gyrus is well established, a fine scale organization of the representations of the digits of the hand has not been fully characterized. Previous neuroimaging studies have failed to find clear evidence for a specificity of digit representations in motor cortex, but rather report a distributed network of control. Reported here are the results of two experiments; in Experiment 1 a sequential finger tapping task produced strong blood oxygen level dependent (BOLD) responses in the contralateral precentral gyrus, but there was a lack of specificity for distinguishing individual representations. A randomly ordered task did accomplish this goal. In the second experiment, a randomly ordered finger-tapping task was used and the findings demonstrated BOLD responses in clusters of voxels specific to movement of a single digit. The region of interest defined for each digit comprised several noncontiguous clusters. A "selectivity index" was developed to quantify the magnitude of the BOLD response to the movement of a specific digit, relative to BOLD response associated with movement of other digits. Strong evidence of BOLD selectivity (albeit not exclusivity) was found in the hemisphere contralateral to the cued digit; however, there was no evidence for an orderly spatial topography. These findings demonstrate that a selectivity of activation is quantifiable, supports a theory of noncontiguous distribution of control, and provides a method for comparing between healthy and impaired populations and investigating changes following training or intervention.
PESO: Prostate Epithelium Segmentation on H&E-stained prostatectomy whole slide images (2018)

Large set of whole-slide-images (WSI) of prostatectomy specimens with various grades of prostate cancer (PCa). More information can be found in the corresponding paper: https://doi.org/10.1038/s41598-018-37257-4 The WSIs in this dataset can be viewed using the open-source software ASAP or Open Slide. Due to the large size of the complete dataset, the data has been split up in to multiple archives. The data from the training set: <strong>peso_training_masks.zip: </strong>Training masks (N=62) that have been used to train the main network of our paper. These masks are generated by a trained U-Net on the corresponding IHC slides. <strong>peso_training_masks_corrected.zip: </strong>A subset of the color deconvolution masks (N=25) on which manual annotations have been made. Within these regions, stain and other artifacts have been removed. <strong>peso_training_colordeconvolution.zip: </strong>Mask files (N=62) containing the P63&amp;CK8/18 channel of the color deconvolution operation. These masks mark all regions that are stained by either P63 or CK8/18 in the IHC version of the slides. <strong>peso_training_wsi_{1-6}.zip: </strong>Zip files containing the whole slide images of the training set (N=62). Each archive contains 10 slides, excluding the last which contains 12. These images are exported at a pixel resolution of 0.48mu/pixels. The data from the test set: <strong>peso_testset_regions.zip: </strong>Collection of annotation XML files with outlines of the test regions. These can be used to view the test regions in more detail using ASAP. <strong>peso_testset_png.zip: </strong>Export of the test set regions in PNG format (2500x2500 pixels per region). <strong>peso_testset_png_padded.zip: </strong>Export of the test regions in PNG format padded with a 500 pixel wide border (3500x3500 pixels per region). Useful for segmenting pixels at the border of the regions. <strong>peso_testset_mapping.csv: </strong>A csv file mapping files from the test set (numbered 1-160) to regions in the xml files. The csv file also contains the label (benign or cancer) for each region. <strong>peso_testset_wsi_{1-4}.zip: </strong>Zip files containing the whole slide images of the test set (N=40). Each archive contains 10 slides of the test set. These images are exported at a pixel resolution of 0.48mu/pixels. This study was financed by a grant from the Dutch Cancer Society (KWF), grant number KUN 2015-7970. <strong>If you make use of this dataset please cite both the dataset itself and the corresponding paper: </strong>https://doi.org/10.1038/s41598-018-37257-4
Digital beamforming for Passive Coherent Location radar (2008)

The paper presents digital beamforming for Passive Coherent Location (PCL) radar. The considered circular antenna array is a part of a passive system developed at Warsaw University of Technology. The system is based on FM radio transmitters. The array consists of eight half-wave dipoles arranged in a circular array covering 360deg with multiple beams. The digital beamforming procedure is presented, including mutual coupling correction and antenna pattern optimization. The results of field calibration and measurements are also shown.
Small incision lenticule extraction (SMILE) versus laser in-situ keratomileusis (LASIK): study protocol for a randomized, non-inferiority trial (2012)

Clinicaltrials.gov NCT01216475.
A large-bias conduction model of polycrystalline silicon films (1994)

There exists a need for a large-bias conduction model of polysilicon films used in VLSI/ULSI and in high power integrated circuits. A large-bias conduction model has been developed by extending the emission-based models of Lu et al. (1983) and Mandurah et al. (1981) valid for small-bias, small-signal conditions. The following large-bias effects have been taken into account: (1) asymmetry of potential distribution around grain boundaries and (2) avalanche multiplication of carriers in the grain boundary layers at high electric fields. Since the exact nature of the grain boundary material is not yet known, and there is no direct method for determining the model parameters relating to grain boundaries, these were extracted by the parametric fitting of resistance versus temperature data of polysilicon resistors near room temperature with the above small-signal resistivity models modified by including Fermi-Dirac distribution. The model has been validated with experimental data on the current-voltage characteristics of ion-beam sputtered polysilicon resistors of different sizes and aspect ratios. The dependence of model parameters relating to grain boundary scattering and avalanche multiplication on the dimensions of resistors have been explained physically. The increased kink effect in polysilicon TFT's may also be predicted from the present theory. Some results on the I-V characteristics of polyresistors trimmed by high current pulses have been discussed qualitatively in the light of the present model. Although the model involves numerical integrations and a few iterations, it is reasonably fast in execution.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Machine Vision Based Automated Tractor Guidance (2003)

Driving an agricultural tractor in the field to perform various farming operations is typically hard for operators due to the long hours of tedious repetitive tasks. Among those tasks, guiding the tractor along crop rows without overrunning plants requires the most attention and is the major cause for operators' fatigue. A smart tractor guidance system, based on artificial vision using a CCD camera, can release the human operator from the monotonous driving task of following crop rows precisely. Not only will it release operators from the tiresome crop row following task but it will also allow them to pay more attention to other operations which will lead to improved performance, increased efficiency, and enhanced safety in farming operations. This paper presents the development of a machine vision based smart navigation system to guide an agricultural tractor following crop rows automatically and accurately. A video camera was installed on the front side of the tractor, and the developed algorithm processed the acquired images and generated appropriate steering signals to steer the tractor. Field tests verified that this smart guidance system could accurately guide a tractor along crop rows in fields at a traveling speed up to 11 km/h.
Tunable photonic-bandgap microcavity waveguides at 1.55 /spl mu/m (2003)

We have designed and fabricated tunable photonic-bandgap microcavities in optical waveguides, with strain modulation via thin-film piezoelectric actuators on deformable membranes. Cavity resonance tunability, with nanometer lattice control, is designed through perturbation on FDTD computations. Device fabrication integrates X-ray nanolithography, piezoelectric microactuators and bulk micromachining.
The quest for high spatial resolution diffusion‐weighted imaging of the human brain in vivo (2019)

Diffusion-weighted imaging, a contrast unique to MRI, is used for assessment of tissue microstructure in vivo. However, this exquisite sensitivity to finer scales far above imaging resolution comes at the cost of vulnerability to errors caused by sources of motion other than diffusion motion. Addressing the issue of motion has traditionally limited diffusion-weighted imaging to a few acquisition techniques and, as a consequence, to poorer spatial resolution than other MRI applications. Advances in MRI imaging methodology have allowed diffusion-weighted MRI to push to ever higher spatial resolution. In this review we focus on the pulse sequences and associated techniques under development that have pushed the limits of image quality and spatial resolution in diffusion-weighted MRI.
Isolation of apolipoproteins from carotenoid-carrying lipoprotein in the serum of chum salmon, Oncorhynchus keta (1988)

Carotenoid-carrying lipoprotein (CCL) was rapidly isolated from the high density lipoprotein (HDL) fraction of the upstream migrating male chum salmon (Oncorhynchus keta) by a single-step density gradient ultracentrifugation. The two apolipoproteins (Mr = 24,000 and 12,000; designated apo-I and apo-II, respectively) were readily dissociated and separated in 0.1% SDS by gel filtration chromatography. Prominent features of the amino acid composition in the CCL included the relative high levels of glutamic acid, alanine, leucine, and lysine, and the low cysteine content. Apo-I, as well as the CCL, was rich in glutamic acid, alanine, leucine, and lysine. Compared to the amino acid composition of apo-I, apo-II included relatively high levels of glycine and tyrosine, and low threonine, serine, and arginine contents. When the intact CCL particle was treated with trypsin, apo-I was rapidly proteolyzed, while apo-II was resistant. However, both apo-I and apo-II isolated from the CCL particle were readily digested with trypsin. This suggested that a different structural arrangement rather than the amino acid compositions of the apolipoproteins was associated with the limited trypsin digestion of the CCL particle. Apo-II may be sheltered from the aqueous environment and lie partly within the CCL particle. The properties of both the HDL fraction and apolipoproteins from pink salmon (Oncorhynchus gorbuscha) were similar to those of the CCL from chum salmon.
Maximally efficient permanent magnet structures (1996)

A general theory is developed for determining the most efficient magnetic structure that generates a specified magnetic field. The structure is assumed to be composed of linear, isotropic magnetized material, occupying a given geometrical region. The efficiency is quantified by a figure of merit defined as the external field energy produced by the magnet divided by the maximum amount of energy that can be stored by the magnetized material. A set of equations is derived that determines the distribution of remanence needed to maximize this figure of merit, and several theorems concerning maximally efficient structures are given. Simple two-dimensional examples are used to illustrate the theory.
System Support for Distributed Energy Management in Modular Operating Systems (2010)

This thesis proposes a novel approach for managing energy in modular operating systems. Our approach enables energy awareness if the resource-management subsystem is distributed among multiple operating-system modules. There are four key achievements: a model for modularization-aware energy management; the support for exposed and distributed energy accounting and allocation; the use of different energy-management interaction protocols; and, finally, the support virtualization of energy effects.
INFLUENCE OF CHLORDIAZEPOXIDE ON THE CAPACITY OF IODIDE CONCENTRATION AND ON THE SECRETARY ACTIVITY OF THE THYROID, STUDIED WITH I$sup 13$$sup 1$ (1963)

Determination of thyroidal radioiodide concentration was performed on lots of 5 adult male rats. A 10- mu C dose of carrier-free NaI/sup 131/ was injected intraperitoneally 1 hr after administration of 20 mg propylthiouracil. One hr after administration of I the animals were sacrificed and the ratio of radioiodide per 100 mg thyroid to radioiodide per 0.1 ml plasma was determined. The drug was administered in doses of 10 and 20 mg/kg, 15 min after and 1 and 2 hr before the radioiodide. Cor the study of secretory activity of the thyroid, adult male mice were administered 10 mu C or carrier-free NaI/sup 131/, and in vivo determinations were begun 48 hr later. Determination were made regularly over a 48-hr period. Chlordiazepoxide was administered intraperitoneally in doses of 2.5, 5, and 10 mg/kg 50 to 52 hr after injection of radioiodide. Results were: chlordiazepoxide produces a reduction in the activity of thyroid iodine concentration in the rat, determinable from the ratio cited above; the reduction is significant only it 20 mg/kg, after the second hr after administration, the ratio dropping to about 80% of the control value. In the mouse, chlordiazepoxide brings about a depression of secretory activity of themore » thyroid at doses of 5 and 10 mg/kg, proportional to the dose; after 48 hr, activity was about 90 and 80% that of the controls, respectively. The drug thus appears to have an indirect effect, similar to the chlorpromazine and phenothiazine groups of drugs. (BBB)« less
Effects of a Chitosan Scaffold Containing TGF‐β1 Encapsulated Chitosan Microspheres on In Vitro Chondrocyte Culture (2004)

The objectives of this study were (1) to develop a three-dimensional chitosan scaffold in combination with transforming growth factor-beta1 (TGF-beta1)-loaded chitosan microspheres and (2) to evaluate the effect of the TGF-beta1 release on the chondrogenic potential of rabbit chondrocytes in the scaffolds. TGF-beta1 was loaded into chitosan microspheres using an emulsion-crosslinking method, resulting in spherical shapes with a size ranging from 0.3 to 1.5 microm. Controlled release of TGF-beta1, as measured by enzyme-linked immunosorbent assay (ELISA), was observed with chitosan microspheres over 7 days. Chitosan solutions (2% and 3%) were fabricated into two types of scaffolds with different pore morphologies and mechanical properties using a freeze-drying technique, with the result that scaffold with higher concentrations showed smaller pores and lower porosity, leading to a much stronger scaffold. The TGF-beta1 microspheres were incorporated into the scaffolds at a concentration of 10 ng TGF-beta1/scaffold and then chondrocytes seeded into each scaffold and incubated in vitro for 2 weeks. The 2% chitosan scaffolds showed higher cell attachment levels than the 3% chitosan scaffolds (P < 0.01), regardless of the TGF-beta1 microspheres. Both the proliferation rate and glycosaminoglycan (GAG) production were significantly higher for scaffolds incorporating TGF-beta1 microspheres than for the control scaffolds without microspheres 10 days after incubation. Extracellular matrix staining by Safranin O and immunohistochemistry for type II collagen both significantly increased in scaffolds containing TGF-beta1 microspheres. These results suggest that the TGF-beta1 microsphere incorporated in scaffolds have the potential to enhance cartilage formation.