gebhart/patrepeval huggingface dataset:
Learning Transferable Policies for Monocular Reactive MAV Control (2016)

The ability to transfer knowledge gained in previous tasks into new contexts is one of the most important mechanisms of human learning. Despite this, adapting autonomous behavior to be reused in partially similar settings is still an open problem in current robotics research. In this paper, we take a small step in this direction and propose a generic framework for learning transferable motion policies. Our goal is to solve a learning problem in a target domain by utilizing the training data in a different but related source domain. We present this in the context of an autonomous MAV flight using monocular reactive control, and demonstrate the efficacy of our proposed approach through extensive real-world flight experiments in outdoor cluttered environments.
PosMed-plus: An Intelligent Search Engine that Inferentially Integrates Cross-Species Information Resources for Molecular Breeding of Plants (2009)

Molecular breeding of crops is an efficient way to upgrade plant functions useful to mankind. A key step is forward genetics or positional cloning to identify the genes that confer useful functions. In order to accelerate the whole research process, we have developed an integrated database system powered by an intelligent data-retrieval engine termed PosMed-plus (Positional Medline for plant upgrading science), allowing us to prioritize highly promising candidate genes in a given chromosomal interval(s) of Arabidopsis thaliana and rice, Oryza sativa. By inferentially integrating cross-species information resources including genomes, transcriptomes, proteomes, localizomes, phenomes and literature, the system compares a user's query, such as phenotypic or functional keywords, with the literature associated with the relevant genes located within the interval. By utilizing orthologous and paralogous correspondences, PosMed-plus efficiently integrates cross-species information to facilitate the ranking of rice candidate genes based on evidence from other model species such as Arabidopsis. PosMed-plus is a plant science version of the PosMed system widely used by mammalian researchers, and provides both a powerful integrative search function and a rich integrative display of the integrated databases. PosMed-plus is the first cross-species integrated database that inferentially prioritizes candidate genes for forward genetics approaches in plant science, and will be expanded for wider use in plant upgrading in many species.
High-Grade Prostate Cancer: Favorable Results in the Modern Era Regardless of Initial Treatment (2012)

Purpose. We performed a retrospective study to determine the outcome of a modern cohort of patients with high-grade (Gleason score ≥ 8) prostate cancer treated with radical prostatectomy, radiation therapy, or hormone therapy. Methods. We identified 404 patients in the South Texas Veteran's Healthcare System Tumor Registry diagnosed with high grade prostate cancer between 1998 and 2008. Mean follow-up was 4.62 ± 2.61 years. End points were biochemical failure-free survival, overall survival, metastasis-free survival, and cancer-specific survival. Results. 5-year overall survival for patients undergoing radical prostatectomy, radiation therapy, and hormone therapy was 88.9%, 76.3%, and 58.9%, respectively. 5-year metastasis-free survival for patients undergoing radical prostatectomy, radiation therapy, and hormone therapy was 96.8%, 96.6%, and 88.4%, respectively, and 5-year cancer-specific survival was 97.2%, 100%, and 89.9%, respectively. Patients with a Gleason score of 10 and pretreatment prostate-specific antigen > 20 ng/mL had decreased 5-year biochemical failure-free and cancer-specific survival. Patients with a pretreatment prostate-specific antigen > 20 ng/mL had decreased 5-year overall survival. Discussion. Even for patients with high-grade disease, the outcome is not as dire in the modern era regardless of primary treatment modality chosen. While there is room for improvement, we should not have a nihilistic impression of how these patients will respond to treatment.
Fast and Reliable Alert Delivery in Mission-Critical Wi-Fi HaLow Sensor Networks (2020)

Rapidly evolving, the Internet of Things imposes new challenges for the developers of wireless networks. Various critical infrastructure monitoring scenarios require fast and reliable alert delivery. In such systems, multiple sensors are entrusted to react to the same emergency event. Thus, it is enough to receive an alert message from any of these sensors. However, such a message shall be reliably delivered as soon as possible. The recently published Wi-Fi HaLow standard defines the Restricted Access Window (RAW) mechanism that coordinates transmissions of numerous devices. Thus, it can improve reliability and reduce delays. The paper is the first to study the usage of RAW in a scenario of emergency alerts, where the alert shall be received from at least one sensor. The paper presents an easy-to-calculate mathematical model of alert delivery with RAW. The model allows dynamic online reconfiguration of RAW parameters to select such parameters that minimize consumed channel timeshare while providing satisfactory reliability and delivery delay for an alert. Intensive performance evaluation shows that the RAW is fruitful for mission-critical data delivery in the considered scenario.
Figure S6 from Macrophage-Derived Cholesterol Contributes to Therapeutic Resistance in Prostate Cancer (2023)

&lt;p&gt;Impact of lupron and enzalutamide on tumor growth&lt;/p&gt;
Thin SiNC/SiOC Coatings with a Gradient of Refractive Index Deposited from Organosilicon Precursor (2020)

In this work, optical coatings with a gradient of the refractive index are described. Its aim was to deposit, using the RF PECVD method, films of variable composition (ranging from silicon carbon-oxide to silicon carbon-nitride) for a smooth change of their optical properties enabling a production of the filter with a refractive index gradient. For that purpose, two organosilicon compounds, namely tetramethyldisilazane and hexamethyldisilazane, were selected as precursor compounds. The results reveal better optical properties of the materials obtained from the latter source. Depending on whether deposited in pure oxygen atmosphere or under conditions of pure nitrogen, the refractive index of the coatings amounted to 1.65 and to 2.22, respectively. By using a variable composition N2/O2 gas mixture, coatings of intermediate magnitudes of “n” were acquired. The optical properties were investigated using both UV-Vis absorption spectroscopy and variable angle spectroscopic ellipsometry. The chemical structure of the coatings was studied with the help of Fourier transform infrared and X-ray photoelectron spectroscopies. Finally, atomic force microscopy was applied to examine their surface topography. As the last step, a “cold mirror” type interference filter with a gradient of refractive index was designed and manufactured.
Direct observation of RAG recombinase recruitment to chromatin and the IgH locus in live pro-B cells (2020)

Abstract The RAG1 and RAG2 proteins introduce double-strand DNA breaks at antigen-receptor loci in developing lymphocytes to initiate V(D)J recombination. How RAG proteins find the correct target locus in a vast excess of non-specific chromatin is not known. Here we measured dynamics of RAG1/RAG2 interactions with chromatin in living pro-B cells. We found that the majority of RAG1 or RAG1/RAG2 complex is in a fast 3D diffusive state, and the residual slow diffusive (bound) fraction was determined by a non-core portion of RAG1, and the PHD domain of RAG2. The RAG proteins exhibited distinct dynamics at the IgH locus. In particular, RAG2 increased the probability of RAG1 binding to IgH , a property that likely explains its non-catalytic role in V(D)J recombination. Our observations reveal how RAG finds its targets in developing B cells. One Sentence Summary Single-molecule imaging of the RAG recombinase reveals its search strategy for chromatin, H3K4me3 and antibody gene loci in living cells.
World Wide Web caching: the application-level view of the Internet (1997)

The Internet has fallen prey to its most successful service, the World Wide Web. The networks do not keep up with the demands incurred by the huge amount of Web surfers. Thus, it takes longer and longer to obtain the information one wants to access via the World Wide Web. Many solutions to the problem of network congestion have been developed in distributed systems research in general and distributed file and database systems in particular. The introduction of caching and replication strategies has proven to help in many situations; therefore, these techniques are also applied to the Web. Although most problems and associated solutions are known, some circumstances are different with the Web, forcing the adaptation of known strategies. This article gives an overview of these differences and currently deployed, developed, and evaluated solutions.
Experimental Uncertainty in Third-Order Susceptibility and Molecular Second Hyperpolarizability Measurements Obtained with Degenerate Four-Wave Mixing. (1995)

Abstract : An uncertainty analysis is performed on a degenerate four-wave mixing scheme used in the determination of the third-order susceptibility and molecular second hyperpolarizability of nonlinear optical materials. Equations are derived based on the root-sum-squares method, which accounts for uncertainty in all applicable experimental parameters. These expressions are incorporated into a computer program, which is used to investigate absolute and relative uncertainties as well as the sensitivity of overall system accuracy to individual parameters. Conclusions are drawn based on the results of the analysis.
Assessing requirements and concerns of potential users of automated driving services progressed by Internet of Things using a co-designer approach (2019)

Road vehicles are becoming increasingly automated and connected due to rapid technological progress and digitalization trends. Vehicle connectivity might improve automated driving (AD) in various ways. While the benefits of convergence of sensor-based technologies and connected-vehicle communications are relatively well analyzed from technological, economical, and legal perspective in recent works, assessing user acceptance remains a challengeable task as many of the benefits of this convergence are not directly observable by the users. This study provides early insights on expectations, requirements and concerns of potential users of AD progressed by Internet of Things solutions based on an online survey conducted in eight European countries. It is a part of the European project AUTOPILOT where different use cases of AD progressed by Internet of Things (IoT) are developed and tested. This contribution summarizes the main results from the survey and discusses their implication for the development of the technology considering the user perspective.
Infrared and visible image fusion with the target marked based on multi-resolution visual attention mechanisms (2017)

During traditional multi-resolution infrared and visible image fusion processing, the low contrast ratio target may be weakened and become inconspicuous because of the opposite DN values in the source images. So a novel target pseudo-color enhanced image fusion algorithm based on the modified attention model and fast discrete curvelet transformation is proposed. The interesting target regions are extracted from source images by introducing the motion features gained from the modified attention model, and source images are performed the gray fusion via the rules based on physical characteristics of sensors in curvelet domain. The final fusion image is obtained by mapping extracted targets into the gray result with the proper pseudo-color instead. The experiments show that the algorithm can highlight dim targets effectively and improve SNR of fusion image.
Nopaline-type Ti plasmid of Agrobacterium encodes a VirF-like functional F-box protein (2015)

During Agrobacterium-mediated genetic transformation of plants, several bacterial virulence (Vir) proteins are translocated into the host cell to facilitate infection. One of the most important of such translocated factors is VirF, an F-box protein produced by octopine strains of Agrobacterium, which presumably facilitates proteasomal uncoating of the invading T-DNA from its associated proteins. The presence of VirF also is thought to be involved in differences in host specificity between octopine and nopaline strains of Agrobacterium, with the current dogma being that no functional VirF is encoded by nopaline strains. Here, we show that a protein with homology to octopine VirF is encoded by the Ti plasmid of the nopaline C58 strain of Agrobacterium. This protein, C58VirF, possesses the hallmarks of functional F-box proteins: it contains an active F-box domain and specifically interacts, via its F-box domain, with SKP1-like (ASK) protein components of the plant ubiquitin/proteasome system. Thus, our data suggest that nopaline strains of Agrobacterium have evolved to encode a functional F-box protein VirF.
Experimental and computational analysis of the ancestry of an evolutionary young enzyme from histidine biosynthesis (2022)

The conservation of fold and chemistry of the enzymes associated with histidine biosynthesis suggests that this pathway evolved prior to the diversification of Bacteria, Archaea, and Eukaryotes. The only exception is the histidinol phosphate phosphatase (HolPase). So far, non-homologous HolPases that possess distinct folds and belong to three different protein superfamilies have been identified in various phylogenetic clades. However, their evolution has remained unknown to date. Here, we analyzed the evolutionary history of the HolPase from γ-Proteobacteria (HisB-N). It has been argued that HisB-N and its closest homologue d-glycero-d-manno-heptose-1,7-bisphosphate 7-phosphatase (GmhB) have emerged from the same promiscuous ancestral phosphatase. GmhB variants catalyze the hydrolysis of the anomeric d-glycero-d-manno-heptose-1,7-bisphosphate (αHBP or βHBP) with a strong preference for one anomer (αGmhB or βGmhB). We found that HisB-N from Escherichia coli shows promiscuous activity for βHBP but not αHBP, while βGmhB from Crassaminicella sp. shows promiscuous activity for HolP. Accordingly, a combined phylogenetic tree of αGmhBs, βGmhBs, and HisB-N sequences revealed that HisB-Ns form a compact subcluster derived from βGmhBs. Ancestral sequence reconstruction and in vitro analysis revealed a promiscuous HolPase activity in the resurrected enzymes prior to functional divergence of the successors. The following increase in catalytic efficiency of the HolP turnover is reflected in the shape and electrostatics of the active site predicted by AlphaFold. An analysis of the phylogenetic tree led to a revised evolutionary model that proposes the horizontal gene transfer of a promiscuous βGmhB from δ- to γ-Proteobacteria where it evolved to the modern HisB-N.
ChemInform Abstract: MASS SPECTROMETRIC STUDIES ON THE VAPOR PHASE COMPOSITION OVER SOLID AND FUSED CESIUM ANTIMONIDE (CS3SB) (1982)

Abstract Die Hauptbestandteile des Dampfes über festem und geschmolzenem C8351) sind, wie Knudsen‐Zellen‐massenspektrometrische Messungen zeigen, Cs, CS 2 , Sb, Sb, und Sb4, die auch über den reinen Metallen zu finden sind.
A Multiagent Approach for Dynamic Enterprise Partnerships (2005)

In this paper a novel approach for multiagent dynamic enterprise partnerships is introduced. Such approach makes possible to model an enterprise system as a set of agents that can be changed at run-time. This feature, makes possible to change the interaction behaviours of the agents and hence their partnerships, dynamically. We developed an infrastructure to allow agents having dynamically reconfigurable behaviours, over the Java Agent Development Framework (JADE). As an example of the application of our approach, a case study related to a virtual enterprise is presented
Nonlinear polarisation effects in fibre Bragg gratings: experiment and theory (2002)

Summary form only given. Recently we demonstrated the operation of an all-fibre nonlinear AND gate based on polarisation coupled gap solitons. In this system when a single pulse was incident upon the grating it was reflected irrespective of its polarisation. However when two pulses with orthogonal polarisations were incident upon the grating a coupled gap soliton was formed which was able to propagate through the grating. In addition to the AND gate we also looked at the polarisation dynamics of a single linearly polarised pulse propagating in a fibre Bragg grating. Briefly we used high nanosecond pulses obtained from a sequence of cascaded fibre amplifiers. These pulses were launched into a 8 cm apodised fibre Bragg grating and at the output light from the two orthogonal polarisations were directed onto a fibre coupled photodiode and a sampling oscilloscope with a time resolution of /spl sim/ 50 ps.
ChemInform Abstract: Synthesis of Diphenyl(nitroaryl)phosphine Oxides via Oxidative Nucleophilic Substitution of Hydrogen in Nitroarenes with Diphenylphosphine Anion. (2009)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Confidence Limits of the Mean (2004)

This chapter contains sections titled: Confidence limits The Central Limit Theorem – the distribution of means Confidence limit of the mean Confidence limits of the mean of small samples Choosing the sample size
Progress Report August 2011 (2011)

Présentation lors de la réunion de travail semestrielle avec Laborelec
Discordant CSF/plasma HIV-1 RNA in individuals on virologically suppressive antiretroviral therapy in Western India (2018)

Aim of this study was to estimate the prevalence of cerebrospinal fluid (CSF)/Plasma HIV-1 RNA discordance in virologically suppressed individuals presenting with incident neurologic symptoms.In this retrospective cohort study conducted between March 1, 2009, and March 1, 2017, HIV-1 infected adults exposed to atleast 12 months of antiretroviral therapy (ART) and having plasma viral load (VL) <1000 copies/mL (virologically suppressed) were included. Among these, individuals presenting with neurologic symptoms during follow-up were assessed for CSF/Plasma HIV-1 RNA discordance by measuring HIV-1 RNA in collected plasma and CSF samples. CSF/plasma HIV-1 RNA discordance was defined as either detectable CSF HIV-1 RNA (VL > 20 copies/mL) with an undetectable plasma RNA (complete viral suppression, VL ≤20 copies/mL) or CSF HIV-1 RNA ≥ 0.5 log10 higher than plasma RNA when plasma VL was between 20 and 1000 copies/mL (low-level viremia, LLV).Out of 1584 virologically suppressed patients, 71 (4.4%) presented with incident neurologic symptoms. Twenty out of 71 (28.2%) patients were diagnosed with CSF/Plasma HIV-1 discordance. Median plasma and CSF VL in patients with discordance was 120 [interquartile range (IQR): <20 to 332.5] and 4250 (IQR: 2550.0- 9615.0) copies/mL, respectively. All 9 individuals in which CSF HIV-1 genotypic resistance testing was done showed mutations that would compromise efficacy of prescribed ART regimen. Prevalence of CSF/plasma HIV-1 RNA discordance was higher among neurologically symptomatic patients with plasma LLV as compared with those with complete viral suppression (70% vs 11.8%, P < .001). The risk of discordance was also greater in patients who received protease inhibitor (PI) containing ART (P < .001) and those on ART regimens with central nervous system (CNS) penetration effectiveness (CPE) value <6 (P = .006).CSF/plasma HIV-1 RNA discordance indicates replication of HIV-1 that has adapted to the CNS or has developed antiretroviral drug resistance. Larger studies should be performed to study incidence of discordance in India. This will help in managing patients presenting with neurologic symptoms on suppressive ART with appropriate neuroeffective therapy.
las UNAEDs como modelo académico de atención y diversificación de la demanda educativa en la UAT (2002)

Resumen es: Como parte del modelo academico curricular flexible de la Universidad Autonoma de Tamaulipas  producto de su reforma academica llevada a cabo reciente...
The Current Status of Prosthetic Heart Valves (1984)

The main objective of the study is to correlate the in vitro fluid dynamic performances of prosthetic heart valves with their in vivo clinical and pathological characteristics. The aim is to clearly document any relationships between in vitro fluid dynamic performance and potential clinical and/or pathological findings and complications. Heart valve prostheses have been used successfully since 1960. Of the nearly 50 different cardiac valves introduced over the past 22 years, many have been discarded due to their lack of success, and of those remaining, several modifications have been made. The most commonly used basic types of prosthetic valves are: (a) caged ball, (b) tilting disc, (c) caged disc, (d) bi-leaflet and (e) bioprostheses. The most serious problems and complications associated with valve prostheses are: (a) thromboembolism, (b) tissue overgrowth, (c) infection, (d) tearing of sewing sutures, (e) hemolysis, (f) valve failure due to material fatigue or chemical change, (g) damage to the endothelial tissue lining of the vessel wall adjacent to the valve, (h) large pressure gradients especially under exercise conditions, and (i) excess regurgitation. Problems (a), (b), (e), (g) - (i) are directly related to the fluid dynamics associated with the different prosthetic valve designs, and are discussed in detail in this paper.
Color Contrast: A Biological Model and its Application for Real Images (2002)

A novel biological model for color contrast is presented. An additional goal of the model was to achieve automatic color correction of still and video images. The model predicts human visual performance according to the physiology of the first and second order of the colorcoded cells in visual system. It is based on the properties of retinal ganglion cells (opponent cells) and cortical cells (double opponent cells) as well as on chromatic adaptation mechanisms in these double opponent colorcoded cells: remote chromatic adaptation. The simulations calculated the perceived image for still images, and were performed in order to correct image colors. The results indicate that the contribution of adaptation mechanisms to color contrast is significant, robust, and enables color correction of still images.
Hematopoietic capacity of connexin43 wild-type and knock-out fetal liver cells not different on wild-type stroma (2003)

In 1995 and 1997 we proposed that gap junctions between stromal and hematopoietic cells formed by connexin43 (Cx43) determine hematopoiesis. If this were the case, are the critical gap junctions in this regard those between hematopoietic and stromal cells, or those between stromal cells alone? To test the first possibility, we compared hematopoietic repopulating capacity between fetal liver hematopoietic cells expressing the different mouse Cx43 genotypes, wild type (WT), hemizygous, or knock-out (KO) on WT host mice stroma. We deleted host glucose phosphate isomerase 1(a) (Gpi-1(a)) stems and then raced identifiable Cx43 WT host fetal liver against congenic donor Cx43 WT, hemizygous, or KO cells in sets, comparing their capacity to form 5 end cells. Hematopoietic capacity did not differ between the Cx43 WT and KO genotypes. The role of Cx43 gap junctions in hematopoiesis remains uncertain.
MR imaging for the quantitative assessment of brain iron in aceruloplasminemia: A postmortem validation study (2021)

R<sub>2</sub>* is highly sensitive to variations in iron concentration in the severely iron-loaded brain, and might be used as a non-invasive measure of brain iron content in aceruloplasminemia and potentially other NBIA disorders.