gebhart/patrepeval huggingface dataset:
Bioactivity of essential oils: a review on their interaction with food components (2015)

Essential oils (EOs) are liquid preparations, produced from plant materials. Although EOs showed a promising bioactivity in vitro, they could interact in foods with some components (fats, proteins, carbohydrates) and pH, thus many authors have reported that a significant effect of EOs toward spoiling and pathogenic microorganisms could be achieved in vivo by using higher amounts of oils. Different methods can be used to assess the bioactivity of EOs (disk diffusion and agar or broth dilution methods); however, there is not a standardized test and researchers propose and use different protocols (evaluating the Minimal Inhibitory Concentration, studying the survival curves, analysis through the scanning electron microscopy, etc.). Thereafter, the scope of this review is a focus on interactions of EOs with proteins, carbohydrates, oils, NaCl, and pH, as well as a brief description on the different protocols to assess their bioactivity both under in vivo and in vitro conditions.
Multifrequency CW-based time-delay estimation for proximity ultrasonic sensors (2002)

With conventional pulse-echo ranging approaches it is difficult to obtain an accurate range measurement needed by a proximity ultrasonic sensor system owing to the limited bandwidth of the transducer. A continuous-wave multifrequency ranging method is presented to accurately measure the proximity distance for an ultrasonic distance sensor system. A novel time-delay estimator is derived based on a nonlinear least-squares-fitting criterion for the case where the received signal amplitude is non-negative owing to the acoustically hard reflection. To minimise the highly oscillatory cost function an efficient two-stage estimation algorithm is proposed. Numerical results show that the estimation algorithm can approach the Cramér–Rao bound as the signal-to-noise ratio increases.
Interference by Anti-C5a Monoclonal Antibodies with the Binding of C5a to Cellular Receptors and the Induction of Enzyme Release from Granulocytes (1991)

A sandwich ELISA based on monoclonal antibodies (MAb) for the quantification of rabbit C5a is only modestly influenced by the presence of MAb 4A3A9, which reacts with an epitope on C5a different from those of MAbs used in the sandwich ELISA. Incubation of rabbit or human granulocytes with C5a in the presence of MAb 4A3A9 results in a less pronounced decrease of the C5a concentration as compared to the concentration measured in the absence of MAb. We interpret the results to indicate an interference of MAb 4A3A9 with the binding of C5a to and/or the dissociation of C5a from its cellular receptor. MAb 4A3A9 is the least effective (25.4% inhibition) among anti-C5a MAbs in inhibiting C5a-induced beta-glucuronidase release from neutrophils. Together, these findings may indicate that a C5a-MAb complex is still able to induce a C5a effect even if MAb does interfere with the binding of ligand to the receptor.
The Structure of Active Centers and the Ethylene Polymerization Mechanism on the Cr/SiO2Catalyst:  A Frontier for the Characterization Methods (2005)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Structure of Active Centers and the Ethylene Polymerization Mechanism on the Cr/SiO2 Catalyst: A Frontier for the Characterization MethodsE. Groppo, C. Lamberti, S. Bordiga, G. Spoto, and A. ZecchinaView Author Information Department of Inorganic, Physical and Materials Chemistry and NIS Centre of Excellence, University of Torino, Via P. Giuria 7, 10125 Torino, Italy Cite this: Chem. Rev. 2005, 105, 1, 115–184Publication Date (Web):January 12, 2005Publication History Received12 July 2004Published online12 January 2005Published inissue 12 January 2005https://pubs.acs.org/doi/10.1021/cr040083shttps://doi.org/10.1021/cr040083sresearch-articleACS PublicationsCopyright © 2005 American Chemical SocietyRequest reuse permissionsArticle Views4251Altmetric-Citations380LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Catalysts,Chromium,Hydrocarbons,Polymerization,Silica Get e-Alerts
Athanasius Kircher, SJ, alegoría de la búsqueda de saber universal (2019)

In a world like ours, where specialization seems to be the irrevocable norm that must govern research activity, the work of Athanasius Kircher, SJ (1602- 1680) underlines the importance of the quest for the universal. Kircher deserves to be described as «the last of the universal sages». The essay Athanasius (2016) intones, inspired by the German sage, a song to the human desire to learn and the need we have to constantly question the inherited ideas. He proposes a search that does justice to the etymology of the word “skeptic”, a term that does not refer to the unbeliever of everything, but to the one that initiates an incessant search.
A Contact Point Intermediate Representation for 6-DOF Haptic Interaction With Dynamic Simulations (2000)

Abstract A new method for integrating a haptic interface device with 3-D dynamic simulations has been implemented which minimizes effects caused by the limited update rate of the simulation and unpredictable communication delays. The new contact point intermediate representation method is compared with a previously implemented method of virtual coupling. Both methods were applied to a recently developed 6 DOF haptic interface device based on Lorentz magnetic levitation connected with a real-time dynamic physical simulation environment. With virtual coupling, the position and orientation data from the interface device and the simulated tool each act as impedance control setpoints for the other, with error and velocity feedback acting as virtual coupling between the two systems. The simple feedback coupling enables the overall stiffness and stability of the system to be tuned easily. In the contact point intermediate representation integration method, the haptic device controller uses additional contact point position and direction information from the simulation to react to user motions by changing the device impedance appropriately at the faster update rate of the controller rather than at the slower simulation rate. The contact point intermediate representation provides a crisper, more responsive feeling than virtual coupling during interaction but is not as easily stabilized. Experimental data from the virtual coupling and a modified contact point intermediate representation implementation are presented.
Speculative Resource Allocation for Packet-Switched Wireless Networks (2005)

In this paper we study benefits of speculative scheduling in wireless networks with elastic services. Common goals of radio resource management (RRM) have traditionally been maximisation of throughput and provisioning of QoS guarantees. Providers of wireless access, however, need to acquire adequate revenue to sustain their business. While throughput maximisation and QoS guarantees increase the quantity or quality, respectively, of the chargeable goods, it has also been shown that by accounting for users' perceptions of what is acceptable from QoS and pricing perspective, provider revenue may increase. We propose and evaluate a packet scheduler for realtime streaming services with the aim to maximise user satisfaction and, thus, improve operator revenue. We also extend an existing service acceptance probability model with a service continuation probability model. The proposed scheduling scheme is compared to a proportional fair scheduler. Preliminary results show that revenue can be increased significantly, while keeping user satisfaction approximately constant. Alternatively, the user satisfaction can be correspondingly improved for fixed revenue.
High Extinction Ratio Mach–Zehnder Modulator Applied to a Highly Stable Optical Signal Generator (2007)

Research into optical modulators has made remarkable progress in recent years. This paper discusses the possibility of applying the high extinction ratio optical modulator to a high-stability and high-frequency (over 100 GHz) optical reference signal generator. High-frequency reference signals are generated by a highly stable optical two-tone generator, which is used for high-rate communication and astronomical application. One method to generate two optical signals is producing them from a pair of laser sources using an optical phase-locked loop for feed back control; however, the optical phase-locked loop has a stability problem in its operation. A good alternative method to the optical phase-locked scheme is the LiNbO <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> Mach-Zehnder (MZ) optical intensity modulator, which is capable of generating two highly stable optical signals (upper sideband and lower sideband components) by applying a sinusoidal microwave signal to an input laser signal. The two optical signals require phase stability better than 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-13</sup> in the Allan standard deviation, vibration robustness, and polarization maintaining capability. The signal coherence loss estimated from the phase stability of the two optical signals generated by the MZ modulator shows that the optical MZ modulator has the ability to generate highly stable optical signals.
On the improvement of gate voltage swings in delta -doped GaAs/In/sub x/Ga/sub 1-x/As/GaAs pseudomorphic heterostructures (1993)

Significant improvements in gate voltage swings in heterostructures prepared by low-pressure metalorganic chemical vapor deposition are discussed. Structures utilizing a compositionally graded In/sub x/Ga/sub 1-x/As channel exhibited a very flat transconductance region of 2 V. The gate voltage swings of single and double delta -doped GaAs/In/sub 0.25/Ga/sub 0.75/As/GaAs structures were 2.5 and 2.8 V, respectively. All structures also exhibited high extrinsic transconductance as well as high saturation current densities.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Integrated system of white LED visible-light communication and power-line communication (2003)

White LEDs offer advantageous properties such as high brightness, reliability, lower power consumption and long lifetime. The biggest potential application for white LEDs is general illumination and lighting. Indoor wireless optical communication systems employing white LED lighting have been proposed. This system is able to offer high QoS due to the high power from this lighting equipment. However, it is difficult for existing offices and households to install the communication cable to the ceiling. An easy wiring system for optical communication using existing power-lines is proposed. This system is emitted as visible-light from LED lighting according to the transmitted signal waveform without demodulating the signal from the power-line. This system is expected to be applicable from the existing lighting easily like exchanging electric bulbs. This integrated system can have a big impact as a new signal transmission system and its economical effect can be great. The basic performance of this system is analyzed. The actual system is built and its feasibility is shown through experiments.
Superconductivity in the First Stage Rubidium Graphite Intercalation Compound C8Rb (1985)

Etude de la supraconductivite par des mesures de susceptibilite magnetique a.c. entre 10 et 40 mK
The Daysimeter: a device for measuring optical radiation as a stimulus for the human circadian system (2005)

Optical radiation incident on the human retina stimulates vision as well as provides time-of-day information to the brain's circadian clock. The visual and circadian systems respond very differently to optical radiation. A device, the Daysimeter, was developed and tested to help progress towards a system of circadian dosimetry. The Daysimeter is a lightweight, head-mounted device that records radiation exposure estimates for both the visual and circadian systems, and is specifically designed for field use. In addition to logging spectrally weighted radiation measurements, it records head position and motion to be utilized as a representation of human circadian activity. This paper provides background on the differences between radiation for the visual and circadian systems, as well as a description of the development and testing of this prototype device.
Association Between Endothelial Function (Assessed on Reactive Hyperemia Peripheral Arterial Tonometry) and Obstructive Sleep Apnea, Visceral Fat Accumulation, and Serum Adiponectin (2015)

Severe OSA, but not visceral fat area or serum adiponectin, was independently associated with endothelial function according to RHI. In addition, impaired endothelial function was reversible following 3 months of CPAP treatment.
Improved Image Segmentation via Cost Minimization of Multiple Hypotheses (2017)

Image segmentation is an important component of many image understanding systems. It aims to group pixels in a spatially and perceptually coherent manner. Typically, these algorithms have a collection of parameters that control the degree of over-segmentation produced. It still remains a challenge to properly select such parameters for human-like perceptual grouping. In this work, we exploit the diversity of segments produced by different choices of parameters. We scan the segmentation parameter space and generate a collection of image segmentation hypotheses (from highly over-segmented to under-segmented). These are fed into a cost minimization framework that produces the final segmentation by selecting segments that: (1) better describe the natural contours of the image, and (2) are more stable and persistent among all the segmentation hypotheses. We compare our algorithm's performance with state-of-the-art algorithms, showing that we can achieve improved results. We also show that our framework is robust to the choice of segmentation kernel that produces the initial set of hypotheses.
Efficient targeted multiallelic mutagenesis in tetraploid potato (Solanum tuberosum) by transient CRISPR-Cas9 expression in protoplasts (2016)

Altered starch quality with full knockout of GBSS gene function in potato was achieved using CRISPR-Cas9 technology, through transient transfection and regeneration from isolated protoplasts. Site-directed mutagenesis (SDM) has shown great progress in introducing precisely targeted mutations. Engineered CRISPR-Cas9 has received increased focus compared to other SDM techniques, since the method is easily adapted to different targets. Here, we demonstrate that transient application of CRISPR-Cas9-mediated genome editing in protoplasts of tetraploid potato (Solanum tuberosum) yielded mutations in all four alleles in a single transfection, in up to 2 % of regenerated lines. Three different regions of the gene encoding granule-bound starch synthase (GBSS) were targeted under different experimental setups, resulting in mutations in at least one allele in 2–12 % of regenerated shoots, with multiple alleles mutated in up to 67 % of confirmed mutated lines. Most mutations resulted in small indels of 1–10 bp, but also vector DNA inserts of 34–236 bp were found in 10 % of analysed lines. No mutations were found in an allele diverging one bp from a used guide sequence, verifying similar results found in other plants that high homology between guide sequence and target region near the protospacer adjacent motif (PAM) site is essential. To meet the challenge of screening large numbers of lines, a PCR-based high-resolution fragment analysis method (HRFA) was used, enabling identification of multiple mutated alleles with a resolution limit of 1 bp. Full knockout of GBSS enzyme activity was confirmed in four-allele mutated lines by phenotypic studies of starch. One remaining wild-type (WT) allele was shown sufficient to maintain enough GBSS enzyme activity to produce significant amounts of amylose.
Micro-computed tomography evaluation of microleakage of Class II composite restorations: An in vitro study (2018)

Tested materials showed statistical differences in microleakage; thus, the null hypothesis has been rejected. Within the limitations of the present experimental procedure, it can be concluded that flowable resin composite should be avoided at the dentin/cementum margin.
Nicotiana benthamiana as model plant for Meloidogyne graminicola infection (2018)

Summary Nicotiana benthamiana is widely used as a model plant to analyse cell biology and to obtain insight into the molecular host-pathogen interaction because it is susceptible to many pathogens. Since N. benthamiana can be transformed easily, it is also used to study pathogens for which it is not a known host. Meloidogyne graminicola has a fairly broad host range of mainly monocots and some dicots but no data were available on the ability of M. graminicola to infect N. benthamiana . In this study, we show that M. graminicola is able to infect and complete its life cycle in N. benthamiana , although our experiments demonstrate a lower susceptibility compared to rice. In addition, M. graminicola was also able to develop in N. tabacum but the reproduction was very low. Therefore, we conclude that N. benthamiana can be considered as a host, while this is not the case for N. tabacum .
Inducing temporal graphs (2006)

We consider the problem of constructing a directed acyclic graph that encodes temporal relations found in a text. The unit of our analysis is a temporal segment, a fragment of text that maintains temporal coherence. The strength of our approach lies in its ability to simultaneously optimize pairwise ordering preferences and global constraints on the graph topology. Our learning method achieves 83% F-measure in temporal segmentation and 84% accuracy in inferring temporal relations between two segments.
Using PCP to control NAT and Firewalls in Multihoming (2012)

This note describes how Port Control Protocol (PCP) can be used to
control NATs and Firewalls in multihoming deployments.
ChemInform Abstract: CYCLOHEXADIENONE ANNULATION VIA α,β‐UNSATURATED FISCHER CARBENE COMPLEXES (1984)

Abstract Der (Juli‐ungesättigte Chromcarbenkomplex (I) reagiert mit den Acetylenen (II) zu den Cyclohexadienonen (III), die durch Einschub einer CO‐Gruppe entstanden sind.
Analysis of 7,8-Dihydro-8-oxo-2′-deoxyguanosine in Cellular DNA during Oxidative Stress (2009)

Analysis of cellular 7,8-dihydro-8-oxo-2'-deoxyguanosine (8-oxo-dGuo) as a biomarker of oxidative DNA damage has been fraught with numerous methodological problems. This is primarily due to artifactual oxidation of dGuo that occurs during DNA isolation and hydrolysis. Therefore, it has become necessary to rely on using the comet assay, which is not necessarily specific for 8-oxo-dGuo. A highly specific and sensitive method based on immunoaffinity purification and stable isotope dilution liquid chromatography (LC)-multiple reaction monitoring (MRM)/mass spectrometry (MS) that avoids artifact formation has now been developed. Cellular DNA was isolated using cold DNAzol (a proprietary product that contains guanidine thiocyanate) instead of chaotropic- or phenol-based methodology. Chelex-treated buffers were used to prevent Fenton chemistry-mediated generation of reactive oxygen species (ROS) and artifactual oxidation of DNA bases. Deferoxamine was also added to all buffers in order to complex any residual transition metal ions remaining after Chelex treatment. The LC-MRM/MS method was used to determine that the basal 8-oxo-dGuo level in DNA from human bronchoalveolar H358 cells was 2.2 +/- 0.4 8-oxo-dGuo/10(7) dGuo (mean +/- standard deviation) or 5.5 +/- 1.0 8-oxo-dGuo/10(8) nucleotides. Similar levels were observed in human lung adenocarcinoma A549 cells, mouse hepatoma Hepa-1c1c7 cells, and human HeLa cervical epithelial adenocarcinoma cells. These values are an order of magnitude lower than is typically reported for basal 8-oxo-dGuo levels in DNA as determined by other MS- or chromatography-based assays. H358 cells were treated with increasing concentrations of potassium bromate (KBrO3) as a positive control or with the methylating agent methyl methanesulfonate (MMS) as a negative control. A linear dose-response for 8-oxo-dGuo formation (r(2) = 0.962) was obtained with increasing concentrations of KBrO3 in the range of 0.05 mM to 2.50 mM. In contrast, no 8-oxo-dGuo was observed in H358 cell DNA after treatment with MMS. At low levels of oxidative DNA damage, there was an excellent correlation between a comet assay that measured DNA single strand breaks (SSBs) after treatment with human 8-oxo-guanine glycosylase-1 (hOGG1) when compared with 8-oxo-dGuo in the DNA as measured by the stable isotope dilution LC-MRM/MS method. Availability of the new LC-MRM/MS assay made it possible to show that the benzo[a]pyrene (B[a]P)-derived quinone, B[a]P-7,8-dione, could induce 8-oxo-dGuo formation in H358 cells. This most likely occurred through redox cycling between B[a]P-7,8-dione and B[a]P-7,8-catechol with concomitant generation of DNA damaging ROS. In keeping with this concept, inhibition of catechol-O-methyl transferase (COMT)-mediated detoxification of B[a]P-7,8-catechol with Ro 410961 caused increased 8-oxo-dGuo formation in the H358 cell DNA.
Simultaneous Enzymatic Cellulose Hydrolysis and Product Separation in a Radial-Flow Membrane Bioreactor (2022)

Hydrolysis is the heart of the lignocellulose-to-bioethanol conversion process. Using enzymes to catalyze the hydrolysis represents a more environmentally friendly pathway compared to other techniques. However, for the process to be economically feasible, solving the product inhibition problem and enhancing enzyme reusability are essential. Prior research demonstrated that a flat-sheet membrane bioreactor (MBR), using an inverted dead-end filtration system, could achieve 86.7% glucose yield from purified cellulose in 6 h. In this study, the effectiveness of flat-sheet versus radial-flow MBR designs was assessed using real, complex lignocellulose biomass, namely date seeds (DSs). The tubular radial-flow MBR used here had more than a 10-fold higher membrane surface area than the flat-sheet MBR design. With simultaneous product separation using the flat-sheet inverted dead-end filtration MBR, a glucose yield of 10.8% from pretreated DSs was achieved within 8 h of reaction, which was three times higher than the yield without product separation, which was only 3.5% within the same time and under the same conditions. The superiority of the tubular radial-flow MBR to hydrolyze pretreated DSs was confirmed with a glucose yield of 60% within 8 h. The promising results obtained by the novel tubular MBR could pave the way for an economic lignocellulose-to-bioethanol process.
Driving Poststroke: Problem Identification, Assessment Use, and Interventions Offered by Canadian Occupational Therapists (2010)

Few clinicians identified driving as a problem post stoke, raising concern that patients attempt to drive on their own or never resume driving because of a lack of attention to driving during their rehabilitation. Poststroke driver assessment and retraining is a critical component of poststroke community reintegration that requires greater awareness by clinicians.