gebhart/patrepeval huggingface dataset:
(R)-(+)- and (S)-(-)-5-Ethyl-5-methyl-1,3-dioxolane-2,4-dione reagents for the direct preparation of .alpha.-hydroxy-.alpha.-methylbutyrate esters: assignment of the absolute configuration of the .alpha.-acetoxy-.alpha.-methylbutyrate ester side chain of quassimarin via total synthesis (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT(R)-(+)- and (S)-(-)-5-Ethyl-5-methyl-1,3-dioxolane-2,4-dione reagents for the direct preparation of .alpha.-hydroxy-.alpha.-methylbutyrate esters: assignment of the absolute configuration of the .alpha.-acetoxy-.alpha.-methylbutyrate ester side chain of quassimarin via total synthesisEric D. Moher, Paul A. Grieco, and Jon L. CollinsCite this: J. Org. Chem. 1993, 58, 15, 3789–3790Publication Date (Print):July 1, 1993Publication History Published online1 May 2002Published inissue 1 July 1993https://pubs.acs.org/doi/10.1021/jo00067a004https://doi.org/10.1021/jo00067a004research-articleACS PublicationsRequest reuse permissionsArticle Views756Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
The association between perceived electronic health record usability and professional burnout among US nurses (2021)

Nurses rated the usability of their current EHR in the low marginal range of acceptability using a standardized metric of technology usability. EHR usability and the odds of burnout were strongly associated with a dose-response relationship.
Design, synthesis and biological activity of cyclic GHRP-6 analogues (2005)

Growth Hormone (GH) secretion is normally stimulated by GHRH. In 1984 C.Y. Bowers and F.A. Momany synthesized the hexa-peptide Growth Hormone Releasing Peptide (GHRP-6) and discovered its ability to stimulate GH release in various species [1]. With the aim to identify the bioactive conformation of GHRP-6, a series of constrained monocyclic analogs were prepared. The cyclizations involved the termini and/or the side chains and, in some of the analogs, a reduced peptide bond was also introduced.
Chroma coding for video at very low bit rates (2002)

Color pictures are usually compressed in a luminance-chrominance coordinate space. We consider the problem of encoding the chrominance information for very low bit rate video coding systems aimed at bit rates in the range 8 to 40 kbps. The challenge is that the chrominance components typically get less than 10 to 20% of the total very low bit rate allocated for the video data. We found that it is sufficient to encode the chrominance information at 1/8 of the luminance resolution in both the horizontal and vertical directions. While, for many of the previous coding methods, the compression is performed independently for the luminance and chrominance coordinates, we propose a coding scheme which exploits the coded luminance data in coding and retrieving the chrominance components. The proposed video coder is an improved extension of an existing luminance-only coder so that color motion video can be coded at very low bit rates under fixed frame and bit rate constraints. It is based on a hybrid waveform coding technique with an implicit model-based component. Very good results were obtained for head-and-shoulders sequences even with chroma rates of less than 7% of the total very low bit rate. In addition, subjective tests indicate that the coded chrominance information improves the visual perception of noisy image features.
ORIGINAL DESIGN OF A WHEELCHAIR ROBOT EQUIPPED WITH VARIABLE GEOMETRY SINGLE TRACKED MECHANISMS (2014)

This paper introduces an originally designed wheelchair robot equipped a variable geometry single tracked mechanism (VGSTM). This mechanism can actively control the robot shape and track tension to adapt for obstacles by two pairs of flippers, so the obstacle clearing ability of traditional wheelchairs can be improved. With the aim of stair-climbing, an optimal solution method of driving moments is proposed to guide the robot design; a tip-over and slippage stability criterion is established to evaluate the robot performance. Finally, the prototype is built, and the stair-climbing experiment is carried out to verify the obstacle clearing ability of the robot.
Semi-automation of Configuration Files Generation for Heterogeneous Multi-tile Systems (2011)

Heterogeneous Multi-Processor System-on-Chips (HMPSoCs) offer an attractive alternative to homogeneous systems to achieve the increasing requirements of modern media-processing applications. Such systems take advantage of the heterogeneity of their processing units (RISC vs. VLIW) combined with efficient memory architecture and a specific communication infrastructure. However, the complexity of such architectures requires efficient programming tools. They rely on software generation flows that have already been widely studied. Connecting several HMPSoCs to form a heterogeneous system is one solution to target the highly demanding applications belonging to the high performance-computing world. Binary code generation for such many-processor architectures faces new challenges. Indeed, binary generation requires a back-end part composed of processor-specific tools like compilers or linkers, that can no longer be configured by hand when dealing with hundreds of processors. We address in this paper the need to automate the whole configuration process of binary generation flows through the study of two important configuration aspects: the memory mapping and communication configurations. We propose a prototype including a semi-automatic configuration generation module that has been successfully applied on a particularly complex application (LQCD).
Does losartan prevent cerebral edema? A preliminary study using a vascular compartment model. (2003)

The results provide strong evidence that losartan may play a role in preventing cerebral edema, and that the renin-angiotensin system plays an important role in postischemic cerebrovascular events.
H-Seg: a horizontal reconstruction volume segmentation method for accurate depth estimation in a computer-generated hologram (2023)

In this work, we introduce a novel approach for depth estimation in a computer-generated hologram by employing horizontal segmentation of the reconstruction volume instead of conventional vertical segmentation. The reconstruction volume is divided into horizontal slices and each slice is processed using a residual U-net architecture to identify in-focus lines, enabling determination of the slice's intersection with the 3D scene. The individual slice results are then combined to generate a dense depth map of the scene. Our experiments demonstrate the effectiveness of our method, with improved accuracy, faster processing times, lower graphics processing unit (GPU) utilization, and smoother predicted depth maps than existing state-of-the-art models.
Physical and mental fatigue: do changes in plasma amino acids play a role? (1991)

Conference Article| April 01 1991 Physical and mental fatigue: do changes in plasma amino acids play a role? E. A. Newsholme; E. A. Newsholme *Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, U.K. Search for other works by this author on: This Site PubMed Google Scholar E. Blomstrand; E. Blomstrand †Pripps Brewery, Research Laboratories, 161 86 Bromma, Sweden Search for other works by this author on: This Site PubMed Google Scholar P. Hassmen; P. Hassmen ‡Department of Psychology, Stockholm University, 106 91 Stockholm, Sweden Search for other works by this author on: This Site PubMed Google Scholar B. Ekblom B. Ekblom §Department of Physiology III, Karolinska Institute, 11 486 Stockholm, Sweden Search for other works by this author on: This Site PubMed Google Scholar Author and article information Publisher: Portland Press Ltd Received: November 21 1990 Online ISSN: 1470-8752 Print ISSN: 0300-5127 © 1991 Biochemical Society1991 Biochem Soc Trans (1991) 19 (2): 358–362. https://doi.org/10.1042/bst0190358 Article history Received: November 21 1990 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Citation E. A. Newsholme, E. Blomstrand, P. Hassmen, B. Ekblom; Physical and mental fatigue: do changes in plasma amino acids play a role?. Biochem Soc Trans 1 April 1991; 19 (2): 358–362. doi: https://doi.org/10.1042/bst0190358 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search Keywords: 5-HT, 5-hydroxytryptamine, 5-HIAA, 5-hydroxyindoleacetic acid, CWT, colour word test This content is only available as a PDF. © 1991 Biochemical Society1991 Article PDF first page preview Close Modal You do not currently have access to this content.
Adaptive designs for power and thermal optimization (2005)

A processor designed to continuously monitor environmental conditions, such as its own power consumption, temperature, and operating frequency, has the potential to dynamically optimize its operating point for maximal power efficiency in real time. The implementation of Montecito's power and thermal control system (Foxton), which is nearing production, provides a basis for discussing opportunities for increasing power efficiency and robustness.
Gold nanoparticles in a cholesteric liquid crystal matrix: self-organization and localized surface plasmon properties (2012)

By combining experimental and calculated optical extinction spectra, scanning electron microscopy and optical microscopy, we investigate the optical properties of a hybrid system consisting of a cholesteric liquid crystal and gold nanoparticles. Close to the air-exposed surface, the liquid crystal film exhibits a structural modulation. In this article, we explore how to use this modulation to drive the formation of gold nanoparticle assemblies and thus to control their localized surface plasmon properties. We found that the penetration of the gold nanoparticles within the liquid crystal modulation depends on the initial concentration of nanoparticles in the colloidal solution. Two distinct regimes are pointed out: (i) at low concentration the nanoparticles are weakly interacting and embedded in a homeotropic environment at the film surface and (ii) at high concentration the penetration of the NPs occurs within the modulation, and their localized surface plasmon resonance is strongly red-shifted due to nanoparticles packing and electromagnetic interactions between the nanoparticles. This surface plasmon resonance shows sensitivity to the light polarization attributed to the formation of anisotropic aggregates oriented by the structural modulation of the liquid crystal.
Run-by-Run Process Control of Metal Sputter Deposition: Combining Time Series and Extended Kalman Filter (2007)

By the time series model, this paper constructed the disturbance model for the aluminum sputter deposition process and derived the extending Kalman filter (EKF) controller based on this new disturbance model. Experimental results reveal that ARI(3,1) model appropriately characterizes the dynamic behavior of the disturbance for the processes. The EKF controller which includes information of process noise and measurement noise is able to regulate the model coefficients automatically as the target is replaced or degrades. In this paper, the d-EWMA controller, time-varying d-EWMA controller, age-based d-EWMA controller, and EKF controller have been applied to aluminum sputter deposition processes for predicting deposition rates and comparing their performances. The application of the EKF controller here is proven to improve the estimating accuracy of the aluminum sputter deposition process significantly, regardless of whether the deposition rates are measured at each run or not.
Transient diffusion and migration to a disk electrode (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTransient diffusion and migration to a disk electrodeMark W. Verbrugge and Daniel R. BakerCite this: J. Phys. Chem. 1992, 96, 11, 4572–4580Publication Date (Print):May 1, 1992Publication History Published online1 May 2002Published inissue 1 May 1992https://pubs.acs.org/doi/10.1021/j100190a081https://doi.org/10.1021/j100190a081research-articleACS PublicationsRequest reuse permissionsArticle Views251Altmetric-Citations60LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Vascular Occlusion Techniques during Liver Resection (2007)

Control of bleeding from the transected liver basically consists of vascular inflow occlusion and control of hepatic venous backflow from the caval vein. Central venous pressure determines the pressure in the hepatic veins and is an extremely important factor in controlling blood loss through venous backflow. Vascular inflow occlusion (Pringle maneuver) involves clamping of the portal vein and the hepatic artery in the hepatic pedicle and gives rise to postischemic, reperfusion injury. Several strategies have been devised to reduce reperfusion injury (pharmacological interventions) or to increase ischemic tolerance of the liver (ischemic preconditioning). Intermittent clamping is recommended in complex liver resections or in patients with diseased livers. The combination of occlusion of vascular inflow and outflow of the liver results in total hepatic vascular exclusion (THVE) and is mainly used in tumors invading the caval vein. During THVE the liver can be cooled by hypothermic perfusion allowing for extended ischemia times. Selective THVE entails clamping of the main hepatic veins in their extrahepatic course, thus preserving caval flow. Safe liver surgery requires knowledge of the regular techniques of vascular occlusion for 'on demand' use when necessitated to reduce blood loss.
Reconstruction of an isolated burst of (non-repetitive) pulses from a single FROG trace (2017)

We propose and demonstrate numerically an approach for reconstructing multiple pulses from a single multiplexed FROG trace, opening the door for complete characterization of laser pulses in isolated pulse-bursts with MHz-THz pulse repetition rate.
Receptor−Ligand-Based Specific Cell Adhesion on Solid Surfaces:  Hippocampal Neuronal Cells on Bilinker Functionalized Glass (2006)

Cell adhesion through binding between specific cell membrane receptors and corresponding cell-adhesion-molecule (CAM)-coated solid surfaces is examined. The morphology of surfaces at various modification steps leading to functionalization with cell-binding CAMs is characterized. In one week neuron cultures, enhanced growth on surfaces modified with neuron-binding versus astrocyte-binding CAMs is observed. However, nonspecific adhesion on a poly-D-lysine-coated positive control surface is found to be even higher. Potential reasons and further studies needed are discussed.
PREDICTIONS OF THE EFFECT OF FLY ASH IN PORTLAND CEMENT MORTAR AND CONCRETE (1971)

THE RELATIONSHIPS BETWEEN INDIVIDUAL FLY ASH VARIABLES AND THE PERFORMANCE OF MORTARS AND CONCRETE CONTAINING FLY ASH ARE DEVELOPED USING PUBLISHED DATA FROM WIDELY DIVERGENT SOURCES (INCLUDING THE RESULTS OF TWO ASTM INTERLABORATORY PROGRAMS). THE COMPRESSIVE STRENGTH, DRYING SHRINKAGE, AND DURABILITY OF THE CONCRETE ARE RELATED TO THE CHANGE IN WATER REQUIREMENT BROUGHT ABOUT BY THE USE OF THE FLY ASH, AND THE CHANGE IN WATER REQUIREMENT IS SHOWN TO BE A FUNCTION OF SPECIFIC FLY ASH VARIABLES. /AUTHOR/
A novel nonionic hydrogel from 2-methyl-2-oxazoline (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA novel nonionic hydrogel from 2-methyl-2-oxazolineYoshiki Chujo, Yutaka Yoshifuji, Kazuki Sada, and Takeo SaegusaCite this: Macromolecules 1989, 22, 3, 1074–1077Publication Date (Print):March 1, 1989Publication History Published online1 May 2002Published inissue 1 March 1989https://pubs.acs.org/doi/10.1021/ma00193a013https://doi.org/10.1021/ma00193a013research-articleACS PublicationsRequest reuse permissionsArticle Views532Altmetric-Citations48LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Danger signals â€“ damaged-self recognition across the tree of life (2014)

Multicellular organisms suffer injury and serve as hosts for microorganisms. Therefore, they require mechanisms to detect injury and to distinguish the self from the non-self and the harmless non-self (microbial mutualists and commensals) from the detrimental non-self (pathogens). Danger signals are "damage-associated molecular patterns" (DAMPs) that are released from the disrupted host tissue or exposed on stressed cells. Seemingly ubiquitous DAMPs are extracellular ATP or extracellular DNA, fragmented cell walls or extracellular matrices, and many other types of delocalized molecules and fragments of macromolecules that are released when pre-existing precursors come into contact with enzymes from which they are separated in the intact cell. Any kind of these DAMPs enable damaged-self recognition, inform the host on tissue disruption, initiate processes aimed at restoring homeostasis, such as sealing the wound, and prepare the adjacent tissues for the perception of invaders. In mammals, antigen-processing and -presenting cells such as dendritic cells mature to immunostimulatory cells after the perception of DAMPs, prime naïve T-cells and elicit a specific adaptive T-/B-cell immune response. We discuss molecules that serve as DAMPs in multiple organisms and their perception by pattern recognition receptors (PRRs). Ca(2+)-fluxes, membrane depolarization, the liberation of reactive oxygen species and mitogen-activated protein kinase (MAPK) signaling cascades are the ubiquitous molecular mechanisms that act downstream of the PRRs in organisms across the tree of life. Damaged-self recognition contains both homologous and analogous elements and is likely to have evolved in all eukaryotic kingdoms, because all organisms found the same solutions for the same problem: damage must be recognized without depending on enemy-derived molecules and responses to the non-self must be directed specifically against detrimental invaders.
Localisation using an image-map (2004)

This paper looks at the problem of building a visual map for later localisation using images from a typical digital camera. The main objective is an ability to query and match images in general position against a large image data set or an image-map. We have achieved a quick localisation in terms of finding a label of the map by finding similar images in the data set. We use affinely invariant Harris corners and sift descriptors to represent 2d images. A kd-tree is used for indexing, matching, and grouping the data set to form a visual map database. For this application, we have improved a voting technique for a 3d structure and a run-time efficiency of kd-tree to allow a quick finding of similar images and a quick localisation. The result can be applied to a more generic localisation (for mobile robotics) and may be integrated in a visual odometry system.
Supplementary Methods and Tables 1-4 from <i>PIK3R1</i> (p85α) Is Somatically Mutated at High Frequency in Primary Endometrial Cancer (2023)

Supplementary Methods and Tables 1-4 from &lt;i&gt;PIK3R1&lt;/i&gt; (p85α) Is Somatically Mutated at High Frequency in Primary Endometrial Cancer
A feature-guided, focused 3D signal permutation method for subtomogram averaging (2022)

Advances in electron microscope instrumentation, cryo-electron tomography data collection, and subtomogram averaging have allowed for the in-situ visualization of molecules and their complexes in their native environment. Current data processing pipelines commonly extract subtomograms as a cubic subvolume with the key assumption that the selected object of interest is discrete from its surroundings. However, in instances when the object is in its native environment, surrounding densities may negatively affect the subsequent alignment and refinement processes, leading to loss of information due to misalignment. For example, the strong densities from surrounding membranes may dominate the alignment process for membrane proteins. Here, we developed methods for feature-guided subtomogram alignment and 3D signal permutation for subtomogram averaging. Our 3D signal permutation method randomizes and filters voxels outside a mask of any shape and blurs the boundary of the mask that encapsulates the object of interest. The randomization preserves global statistical properties such as mean density and standard deviation of voxel density values, effectively producing a featureless background surrounding the object of interest. This signal permutation process can be repeatedly applied with intervening alignments of the 3D signal-permuted subvolumes, recentering of the mask, and optional adjustments of the shape of the mask. We have implemented these methods in a new processing pipeline which starts from tomograms, contains feature-guided subtomogram extraction and alignment, 3D signal-permutation, and subtomogram visualization tools. As an example, feature-guided alignment and 3D signal permutation leads to improved subtomogram average maps for a dataset of synaptic protein complexes in their native environment.