gebhart/patrepeval huggingface dataset:
Correlation between Surgical Manipulations and the Variation of Surgeon’s Heart Rate in Brain Surgery: Technical Note (2013)

For improvement of surgical performance and safety, we record surgeries by video cameras. However, analysis of the video records is time consuming. To help this task, we are developing methods to automatically mark up significant time points in the surgery. As a possible mean for the marking, we focused on the surgeon's heart rate. During a craniotomy of an intracranial glioma, we recorded the surgeon's electrocardiogram using a telemeter and measured the R-to-R interval (RRI). We detected the stable state of heart rate as a peak-to-peak RRI of less than 5% of the mean of RRI data from 15 consecutive heartbeats. We also quantified the frequency of brain touches by the surgeon under the surgical microscope. We examined the association between the stability of surgeon's heart rate and the brain touches using a chi-square test. As the result, the stable state of surgeon's heart rate was associated with the brain touches (p < 0.05, odds ratio 5.1). We edited a one-minute digest video of the surgery based on only the heart rate data, and it was sufficient to understand how the surgery was preceded.
Alias Detection in Malicious Environments. (2006)

Alias detection is a challenging task critical in several areas such as the intelligence community, social network analysis, databases, biology, and marketing. Problem domains can be as simple as datasets containing accidentally replicated data, or as complex as populations containing criminals or terrorists wielding multiple identities. Teasing out aliases or near aliases in the later case is a serious and challenging problem. We propose an unsupervised information theoretic approach for automatically detecting aliases in malicious environments by observing the behaviors of the entities. Our model discovers the most informative observations (e.g. emails, phone calls, relational data) between entities and then compares them to identify entities exhibiting similar behaviors. We test our model by applying it to the task of discovering aliases in a standard synthetic world of interrelated individuals. Given our system’s top-20 guesses, we extracted with 80 % accuracy the true aliases of a given entity.
Prognostic and Clinicopathological Significance of MiR-155 in Hematologic Malignancies: A Systematic Review and Meta-analysis (2019)

<b>Background:</b> Aberrant miR-155 expression has been reported in various types of hematologic malignancies. However, the prognostic and clinicopathological value of miR-155 remains unclear. Here, we performed this systemic review and meta-analysis to comprehensively evaluate the prognostic and clinicopathological significance of miR-155 expression in hematologic malignancies. <b>Methods:</b> We systematically searched the PubMed, EMBASE, ISI Web of Science, Cochrane library databases and OVID to identify eligible studies published from Jan 1, 2008 to Aug 1, 2018. The pooled hazard ratios (HRs) and odds ratios (ORs) with corresponding 95% confidence intervals (CIs) were used to detect the prognostic and clinicopathological role of miR-155 in hematologic malignancies. <b>Results:</b> A total of 18 studies including 2316 patients were enrolled in the present meta-analysis, indicating significant association between elevated miR-155 expression and poor overall survival (OS) in 2114 patients (pooled HR = 1.72, 95%CI [1.50-1.97], p<0.001). Elevated miR-155 expression level was related to shorter event free survival (EFS, pooled HR = 1.55, 95%CI [0.94-2.57], P=0.002), disease free survival (DFS, pooled HR = 1.38, 95%CI [1.13-1.68], P=0.001), progress free survival (PFS, pooled HR = 1.58, 95%CI [1.06-2.35], p<0.001) and treatment free survival (TFS, pooled HR = 1.67, 95%CI [1.16-2.39], P=0.006). Additionally, overexpression of miR-155 was found to be significantly related to FLT3/ITD presence (OR=4.751, 95%CI [3.229-6.990], P<0.001), more WT1 mutation (OR=2.090, 95%CI [1.240-3.522], P=0.006) and less CEBPA mutation (OR=0.477, 95%CI [0.286-0.794], P=0.004) in 552 AML patients. <b>Conclusion:</b> MiR-155 expression was found to be associated with several leukemia-related phenotype and poor prognosis in hematologic malignancies. Therefore, miR-155 overexpression might be a convinced unfavorable prognostic indicator that helps the clinical decision-making process.
Issues and etiquette concerning use of shared measurement data (2007)

In this note we discuss issues surrounding how to provide and use network measurement data made available for sharing among researchers. While previous work has focused on the technical details of enabling sharing via traffic anonymization, we focus on higher-level aspects of the process such as potential harm to the provider (e.g., by de-anonymizing a shared dataset) or interactions to strengthen subsequent research (e.g., helping to establish ground truth). We believe the community would benefit from a dialog regarding expectations and responsibilities of data providers, and the etiquette involved with using others' measurement data. To this end, we provide a set of guidelines that aim to aid the process of sharing measurement data. We present these not as specific rules, but rather a framework under which providers and users can better attain a mutual understanding about how to treat particular datasets.
Comparison of flux switching and surface mounted permanent magnet generators for aerospace applications (2010)

For embedded power generation within civil gas turbine engines, generators are anticipated to endure high rotor speeds coupled with large rotor diameters. With variable frequency permanent magnet generators finding increased roles due to the perceived higher torque density, the issue of rotor integrity becomes a critical issue. Although banding has been previously used in surface mounted PM (SPM) machines, they inevitably increase the airgap and hence reduce the torque capability of the machine. The flux-switching PM (FSPM) machine has been an intense topic of research for many years. By combining its armature and field sources in the stator, its rotor is a passive single piece, salient steel lamination, making it inherently suitable for high speed applications. This paper compares both machines when optimised for high speed applications by designing the rotors of both machines for mechanical integrity and comparing the electromagnetic performance.
In vitro and in vivo studies of PEO-grafted blood-contacting cardiovascular prostheses (2000)

The initial step of thrombus formation on blood-contacting biomaterials is known to be adsorption of blood proteins followed by platelet adhesion. Poly(ethylene oxide) (PEO) has been frequently used to modify biomaterial surfaces to minimize or prevent protein adsorption and cell adhesion. PEO was grafted onto a number of biomaterials in our laboratory. Nitinol stents and glass tubes were grafted with PEO by priming the metal surface with trichlorovinylsilane (TCVS) followed by adsorption of Pluronic and y-irradiation. Nitinol stents were also coated with Carbothane for PEO grafting. Chemically inert polymeric biomaterials, such as Carbothane, polyethylene, silicone rubber, and expanded polytetrafluoroethylene (e-PTFE), were first adsorbed with PEO-polybutadiene-PEO (PEO-PB-PEO) triblock copolymers and then exposed to gamma-irradiation for covalent grafting. For PEO grafting to Dacron (polyethylene terephthalate), the surface was sequentially treated with PEO-PB-PEO and Pluronics followed by gamma-irradiation. In vitro studies showed substantial reduction in fibrinogen adsorption and platelet adhesion to the PEO-grafted surfaces compared with control surfaces. Fibrinogen adsorption was reduced by 70-95% by PEO grafting on all surfaces, except for e-PTFE. The platelet adhesion corresponded to the fibrinogen adsorption. When the PEO-grafted surfaces were tested ex vivo/in vivo, however, the expected beneficial effect of PEO grafting was inconsistent. The beneficial effect of the PEO grafting was most pronounced on the PEO-grafted nitinol stents. Thrombus formation was reduced by more than 85% by PEO grafting on metallic stents. Only moderate improvement (i.e. 35% decrease in platelet deposition) was observed with PEO-grafted tubes of polyethylene, silicone rubber, and glass. For PEO-grafted heart valves made of Dacron, however, no effect of PEO grafting was observed at all. It appears that the extent of thrombus formation on PEO-grafted biomaterials was directly related to the extent of tissue damage during implantation surgery. Platelets can be activated and form aggregates in the bulk blood, and the formed platelet aggregates may be able to deposit on the PEO monolayer overcoming its repulsive property. Our studies indicate that the testing of in vitro platelet adhesion should include adhesion of large platelet aggregates, in addition to adhesion of individual platelets. Furthermore, the surface modification methods should be improved over the current monolayer grafting concept so that the repulsive force by the grafted PEO layers is large enough to prevent adhesion of platelet aggregates formed in the bulk blood before arriving at the biomaterial surface.
Physical localization of the flocculation gene FLO1 on chromosome I of Saccharomyces cerevisiae (1993)

The genetics of flocculation in the yeast Saccharomyces cerevisiae are poorly understood despite the importance of this property for strains used in industry. To be able to study the regulation of flocculation in yeast, one of the genes involved, FLO1, has been partially cloned. The identity of the gene was confirmed by the non-flocculent phenotype of cells in which the C-terminal part of the gene had been replaced by the URA3 gene. Southern blots and genetic crosses showed that the URA3 gene had integrated at the expected position on chromosome I. A region of approximately 2 kb in the middle of the FLO1 gene was consistently deleted during propagation in Escherichia coli and could not be isolated. Plasmids containing the incomplete gene, however, were still able to cause weak flocculation in a non-flocculent strain. The 3' end of the FLO1 gene was localized at approximately 24 kb from the right end of chromosome I, 20 kb centromere-proximal to PHO11. Most of the newly isolated chromosome I sequences also hybridized to chromosome VIII DNA, thus extending the homology between the right end of chromosome I and chromosome VIII to approximately 28 kb.
Crystallization and self-assembly of shape-complementary sequence-defined peptoids (2021)

Shape complementarity between polymers is a hallmark of biological systems ( e.g. DNA base pairing and protein binding interactions). Here we explore the role of shape complementarity between sequence-defined N -alkyl peptoids in crystal lattices.
Root exudates of Brachiaria humidicola, a tropical pasture grass, and its effect on nitrification and soil microorganisms (2007)

Nitrification is an important biological process in global nitrogen cycling whereby&#13;\nammonia is converted to nitrite and nitrate by nitrifying bacteria (species of&#13;\nNitrosomonas, Nitrospira and Nitrobacter). The nitrification products are vulnerable to&#13;\nleaching and denitrification: an estimated 45% of applied fertilizer is lost by leaching and&#13;\n10% to 30.....
MAVIS: a non-invasive instrument to measure area and volume of wounds (1998)

Accurate measurement of the physical size of wounds is vital for assessment of the progress of healing. An instrument has been developed to measure area and volume of skin wounds, ulcers, and pressure sores. MAVIS--Measurement of Area and Volume Instrument System-is based on the principle of colour coded structured light. A set of parallel stripes of alternating colours is projected onto the wound area at an angle of approximately 45 degrees and is recorded by a CCD camera. From the known position of the focal points of projector and camera, and from the observed intersection points of the stripes of light with the wound surface, a computer calculates a three-dimensional map of the observed wound. The volume of the wound is defined as the volume of the region sandwiched between the observed surface and the original healthy skin surface which is simulated by cubic spline interpolation. This paper compares the performance of the instrument with three traditional wound measurement techniques using results obtained from a clinical trial involving 50 patients. Traditional area measurement techniques such as transparency tracings produce results with standard deviations between 4% (large wounds) and up to 20% (small wounds) of the measured mean value. MAVIS measurements reduce these standard deviations by 3-5%. Measuring the wound volume by alginate casts produces errors in volume figures between 5% and 40%. Standard deviations of MAVIS results are 5% smaller on average. The results demonstrate that MAVIS yields more reproducible results with a minimum of inter-observer error. The instrument does not make contact with the wound, provided visual records and measurements are made in less then 5 min. It is not suitable for undermined, very deep or very large wounds.
Easy impossibility proofs for distributed consensus problems (1985)

Article Free Access Share on Easy impossibility proofs for distributed consensus problems Authors: Michael J. Fischer Yale University, New Haven, CT Yale University, New Haven, CTView Profile , Nancy A. Lynch Mass. Inst. of Tech., Cambridge, MA Mass. Inst. of Tech., Cambridge, MAView Profile , Michael Merritt AT&T Bell Labs., Murray Hill, NJ and Mass. Inst. of Tech., Cambridge, MA AT&T Bell Labs., Murray Hill, NJ and Mass. Inst. of Tech., Cambridge, MAView Profile Authors Info & Claims PODC '85: Proceedings of the fourth annual ACM symposium on Principles of distributed computingAugust 1985 Pages 59–70https://doi.org/10.1145/323596.323602Online:01 August 1985Publication History 47citation743DownloadsMetricsTotal Citations47Total Downloads743Last 12 Months26Last 6 weeks7 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Electrochemical Properties of Rechargeable Lithium Batteries with Sulfur-Containing Composite Cathode Materials (2006)

Nanosized powder prepared by the solid-state chemical reaction method was added to sublimed sulfur cathode to form a composite material for lithium-sulfur rechargeable batteries. Lithium-sulfur battery systems, in which sublimed sulfur cathodes with nanosized powder were used, showed an improvement in cycle life and discharge capacity (compared to regular systems). From the results reported herein, it is confirmed that the addition of nanosized powder to sublimed sulfur has a positive effect on polysulfides adsorption, and also has a catalytic effect that promotes the lithium-sulfur redox reaction. Furthermore, it was found that the presence of nanosized in the composite sulfur cathodes increases their porosity, which has a positive effect on their kinetics.
Characterization of Phase and Amplitude Quantization Effects in a Direct Digital Synthesis-based Waveform Generator for Future Software-Defined GPS Payloads (2018)

This paper describes a software-defined GPS signal generator with a direct digital synthesis (DDS) architecture to examine the effects of quantization on a signal. We explore the power and cardinality of spurious frequency components due to phase and amplitude quantization on the generated signal. MATLAB® models are developed to match the hardware that is implemented in a field programmable gate array (FPGA) with a high speed digital-to-analog converter (DAC). Once the MATLAB model is validated against hardware, it is used to determine the optimal phase and amplitude resolution for given implementation.
Smart sensor architecture for vital signs and motor activity monitoring of wheelchair' users (2012)

The development of a smart sensor architecture for health status monitoring and daily motor activity of wheelchair users is considered. Modularity of solution and compatibility of the architecture with IEEE1451 standard for smart sensors were part of the requirements. Thus the work presents a microcontroller-based platform compatible with IEEE 1451.4 standard for vital signs and motor activity assessment of wheelchair users. The identification of the wheelchair user is done using the LF RFID technology through a RFID reader connected to the platform. The signals from unobtrusive sensors embedded in the wheelchair characterized by plug-and-play and auto-identification capabilities are acquired and primary processed at the platform level and transmitted using IEEES02.15.4 wireless communication protocol to a server application implemented in a host PC. Referring to the embedded sensors considered in the present approach, photoplethysmography, skin conductivity, and ballistocardiography are used for cardiorespiratory assessment while a 3D accelerometer is used for motor activity assessment. Elements of human-machine-interface (HMI) implementation and several experimental results are included in the paper.
Drainage Pathway of the Superior Petrosal Vein Evaluated by CT Venography in Petroclival Meningioma Surgery (2012)

Objectives This study aimed to clarify the drainage location of the superior petrosal vein (SPV) in relation to Meckel's cave and the internal acoustic meatus (IAM) and to discuss its significance in petroclival meningioma surgery. Design Prospective clinical study. Setting Hospital-based. Participants Five patients with petroclival meningioma and 50 patients (primarily unruptured supratentorial aneurysm patients, with a few hemifacial spasm patients) with no posterior fossa lesions. Main Outcome Measures On computed tomography venography (CTV), the drainage site was classified into three patterns based on its relationship to Meckel's cave and the IAM: Meckel's cave type, Intermediate type, and Meatal type. Results In all patients, the SPV was patent and emptied into the superior petrosal sinus (SPS). In patients without posterior fossa lesions, 35% had Meckel's cave type, 54% had Intermediate type, and 11% had Meatal type. Of the five patients with petroclival meningioma, three had Intermediate type, and two had Meckel's cave type. Conclusion The SPV is a significant vein that should be preserved to prevent venous complications. Preoperative knowledge of the SPV drainage site is helpful for planning the approach and preserving the SPV in petroclival meningioma surgery.
ChemInform Abstract: The Inhibition of Zinc Corrosion by Bisaminotriazole and Other Triazole Derivatives. (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Repair of the U L 21 Locus in Pseudorabies Virus Bartha Enhances the Kinetics of Retrograde, Transneuronal Infection In Vitro and In Vivo (2008)

The attenuated pseudorabies virus (PRV) strain Bartha contains several characterized mutations that affect its virulence and ability to spread through neural circuits. This strain contains a small genomic deletion that abrogates anterograde spread and is widely used as a retrograde-restricted neural circuit tracer. Previous studies showed that the retrograde-directed spread of PRV Bartha is slower than that of wild-type PRV. We used compartmented neuronal cultures to characterize the retrograde defect and identify the genetic basis of the phenotype. PRV Bartha is not impaired in retrograde axonal transport, but transneuronal spread among neurons is diminished. Repair of the U(L)21 locus with wild-type sequence restored efficient transneuronal spread both in vitro and in vivo. It is likely that mutations in the Bartha U(L)21 gene confer defects that affect infectious particle production, causing a delay in spread to presynaptic neurons and amplification of infection. These events manifest as slower kinetics of retrograde viral spread in a neural circuit.
One-Step Synthesis of Unsymmetrical N-Alkyl-N′-aryl Perylene Diimides (2014)

An efficient and facile protocol for the synthesis of unsymmetrical N-alkyl-N'-aryl perylene diimides is reported that circumvents the need for multiple reaction steps. A number of unsymmetrical perylene diimides containing a solubilizing swallowtail alkyl group and a variety of substituted aryl groups can be prepared in a single step from a simple mixture of amines.
Application of Loop Frame of Reference to Power Flow Tracing and Loss Allocation (2006)

This paper introduces a new power flow tracing and subsequently loss allocation method based on loop analysis. The knowledge of the loop paths aids in the visualisation of presumed transfer of power throughout the transmission network. A formalised process of loop identification, based on graph theory, is introduced to ensure that each loop contains at least one active source. This way, the system losses can be readily and justifiably allocated to the active sources in the network without involving any approximations. The proposed method is applied to both a small test system and the IEEE 14-bus test system, demonstrating the features and limitations of the proposed methodology.
[Use of transconjunctival cryoapplication in chronic pars planitis with involvement of peripheral retina and choroid]. (1993)

The transconjunctival cryoapplication was performed in 8 patients (13 eyes) with the recurrent pars planitis and the simultaneous involvement of peripheral retina and choroid. Before the surgery, the peripheral fundus of the eye was examined with the Goldmann three-mirror lens and afterwards, the cryoapplication of lesions was performed. The topical treatment, dexamethasone and indomethacin drops, followed the surgery only. In all cases the inflammation disappeared but the macular edema and vitreal exudation regressed slowly. The considerable improvement of visual acuity was achieved in 8 eyes (61%). So far, the results of the observations are satisfactory and they entitle the authors to carry on the application of the treatment mentioned above.
Development of an adult mouse model for studies on protection against rotavirus (1990)

Although mice have been used as an animal model for studies on rotavirus disease, these studies have been limited by the short time period after birth during which mice are susceptible to rotavirus illness (i.e., approximately 15 days). To overcome this limitation, an adult mouse model was developed in which the endpoint was infection rather than illness. The model developed utilized a strain of mouse rotavirus (EDIM) adapted to grow in culture by multiple passages in MA104 cells. The second cell culture passage of EDIM caused severe diarrhea in neonatal BALB/c mice, and little or no amelioration of disease was observed after nine cell culture passages, even when this preparation was plaque purified. Oral administration of 2 x 10(3) PFU of passage 9 also consistently caused infection of mice 4, 10, 15, 30, 60, 120, and 180 days of age as determined by viral shedding and seroconversion. Reinoculation of these mice with the same virus preparation at 2, 3, or 4 months after the first inoculation produced no evidence of reinfection. In contrast, infection of neonatal mice with the heterotypic WC3 bovine rotavirus did not prevent reinfection with culture-adapted EDIM. Thus, this strain of EDIM caused consistent infection of previously uninoculated neonatal and adult BALB/c mice and produced homotypic but not heterotypic protection against reinfection.