gebhart/patrepeval huggingface dataset:
High power electrostatic motor and generator using electrets (2004)

For application to a micro-machined gas turbine, we first designed the motor/generator using electrets. Theoretical calculation confirmed that the motor/generator generates 30.4 W at a rotational speed of 1 Mrpm after its electrode design is optimized. Next, we proposed a novel circuit using LC resonance for the generator, which can avoid the charging-discharging loss of the parasitic capacitance. And we confirmed that the circuit could generate over 80% output of the theoretical maximum. Lastly, we developed an electret-charging equipment using Corona discharge. Using it, an electret was charged, showing the average surface voltage of 354 V and the standard deviation of 16 V.
Results from a Phase IIA Parallel Group Study of JNJ-40346527, an Oral CSF-1R Inhibitor, in Patients with Active Rheumatoid Arthritis despite Disease-modifying Antirheumatic Drug Therapy (2015)

Although adequate exposure and effective peripheral target engagement were evident, JNJ-40346527 efficacy was not observed in patients with DMARD-refractory active RA. ClinicalTrials.gov identifier: NCT01597739. EudraCT Number: 2011-004529-28.
The effect of caput succedaneum on oxygen saturation measurements (1990)

Advances in oximetry have allowed the obstetrician to measure oxygen saturation in the fetus with non-invasive transcutaneous techniques. The influence of caput succedaneum formation on the oxygen saturation results obtained with a pulse oximeter was studied in 30 newborn infants. Caput was associated with a reduced oxygen saturation reading (mean reduction of 15%; P less than 0.001). This effect is partly due to a true drop in local tissue oxygenation but is exacerbated by a systematic error intrinsic to the physics of spectrophotometry. If continuous intrapartum oximetry is ever to become a part of routine obstetric monitoring then probes that pass through the cervix beyond the caput of the presenting part will be required if erroneously low readings are to be avoided.
Oxygen atom transfer in the oxidations of dimethyl sulfide and dimethyl sulfoxide by bis(bipyridine)oxo(pyridine)ruthenium(2+) (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOxygen atom transfer in the oxidations of dimethyl sulfide and dimethyl sulfoxide by bis(bipyridine)oxo(pyridine)ruthenium(2+)Lee Roecker, John C. Dobson, William J. Vining, and Thomas J. MeyerCite this: Inorg. Chem. 1987, 26, 5, 779–781Publication Date (Print):March 1, 1987Publication History Published online1 May 2002Published inissue 1 March 1987https://pubs.acs.org/doi/10.1021/ic00252a029https://doi.org/10.1021/ic00252a029research-articleACS PublicationsRequest reuse permissionsArticle Views444Altmetric-Citations84LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The Design and Development of an Omni-Directional Mobile Robot Oriented to an Intelligent Manufacturing System (2017)

In order to transport materials flexibly and smoothly in a tight plant environment, an omni-directional mobile robot based on four Mecanum wheels was designed. The mechanical system of the mobile robot is made up of three separable layers so as to simplify its combination and reorganization. Each modularized wheel was installed on a vertical suspension mechanism, which ensures the moving stability and keeps the distances of four wheels invariable. The control system consists of two-level controllers that implement motion control and multi-sensor data processing, respectively. In order to make the mobile robot navigate in an unknown semi-structured indoor environment, the data from a Kinect visual sensor and four wheel encoders were fused to localize the mobile robot using an extended Kalman filter with specific processing. Finally, the mobile robot was integrated in an intelligent manufacturing system for material conveying. Experimental results show that the omni-directional mobile robot can move stably and autonomously in an indoor environment and in industrial fields.
In situ observation of lithium metal plating in a sulfur-based solid electrolyte for all-solid-state batteries (2019)

The <italic>in situ</italic> AES/AEM technique for practical all-solid-state batteries with sulfur-based solid electrolytes was developed and the real time observation of Li dendrite growth was successfully achieved.
Deformation of swollen erythrocytes provides a model of sickling- induced leak pathways, including a novel bromide-sensitive component (1994)

Deoxygenation-induced red blood cell (RBC) sickling probably activates multiple cation leak pathways. In an attempt to model this, we examined the net passive K efflux ("K leak") from normal and sickle RBCs undergoing elliptical deformation in hypotonic media (200 mOsmol/L). This hypotonic deformation activates two deformation-dependent K leak pathways that are not detectable during the balanced leak (Kefflux = Nainflux) resulting from deformation of RBCs in isotonic medium. These are (1) a calcium-dependent leak component and (2) a novel leak pathway that is inhibited by substitution of bromide (but not sulfamate) for chloride, which converts the unbalanced K leak (Kefflux > Nainflux) of hypotonic deformation to a residual balanced leak. This dramatic effect of hypotonic deformation is reversible, is detected in both normal and sickle RBCs, and is inhibited significantly by 4,4'-diisothiocyano-2,2'-stilbene disulfonate. Remarkably, bromide also inhibits by 55% the K leak resulting from authentic deoxygenation-induced RBC sickling and, thereby, blunts the imbalance of accompanying monovalent cation leaks. The unique effect of bromide is not readily explainable on the basis of known behaviors of known ion leak/transport pathways. The mechanical threshold for triggering K leak during hypotonic deformation is at applied shear stress of 164 dyne/cm2, a value similar to the abnormal susceptibility we previously found for oxygenated sickle RBCs during isotonic deformation. These data suggest that membrane stretch accompanying hypotonic deformation activates the same multiple leak pathways that contribute to net K leak during authentic RBC sickling, including a previously unknown bromide-sensitive leak.
Security Technologies for SoCs (2005)

Abstract- Application area of SoC has been spread to various social infrastructures handling &amp;amp;quot;Trust &amp;amp;quot; and &amp;amp;quot;Value &amp;amp;quot; as systems for e-commerce and e-government. New technologies on security are required in design of SoC, for examples, implementations of security cores for cryptography and hash functions, protection of programs and data on SoC from attacking, and secure design/fabrication/test flow for SoC. In this talk, new problems and solutions for secure SoC design are presented. As an example of the security technologies,
Exploring variation in binding of Protein A and Protein G to immunoglobulin type G by isothermal titration calorimetry (2011)

Bacterial Protein A (PrtA) and Protein G (PrtG) are widely used for affinity purification of antibodies. An understanding of how PrtA and PrtG bind to different isotypes of immunoglobulin type G (IgG) and to their corresponding Fc fragments is essential for the development of PrtA and PrtG mimetic ligands and for the establishment of generic processes for the purification of various antibodies. In this paper, the interactions between the two IgG-binding proteins and IgG of two different subclasses, IgG1 and IgG4, as well as their analogous Fc fragments have been studied by isothermal titration calorimetry. The results indicate that both protein ligands bind IgG and Fc fragments strongly with Ka values in the range of 10(7) -10(8) M(-1) and for both ligands, the interaction with both IgG isotypes is enthalpically driven though entropically unfavorable. Moreover, variation in the standard entropic and standard enthalpic contribution to binding between the two isotypes as well as between IgG and Fc fragment implies that the specific interaction with PrtA varies according to IgG isotype. In contrast to PrtA, PrtG bound to F(ab')(2) fragment with a Ka value of 5.1 × 10(5) M(-1) ; thus underscoring the usefulness of PrtA as a preferred ligand for generic antibody purification processes.
Coronary artery disease trends in Japan. (1994)

Japan has experienced great socioeconomic development together with industrialization, urbanization and motorization since 1945. This has resulted in dramatic changes in both the frequency of disease and the spectrum of diseases, as well as in a rapid increase in the elderly population. Changes in eating patterns during the past 40 to 50 years seem to be a major factor in this evolution. Departure from the traditional Japanese diet, which was very high in salt and low in fat and protein (currently the diet is 25% calories from fat, 60% from carbohydrate and 15% from protein and 12 gm salt/day), has been associated with a reduced incidence of stroke, but not with an increase in coronary heart disease mortality. Therefore, the current Japanese diet may be an optimal eating pattern for maintaining health. However, since the exposure to increased fat calories is recent, future trends must be carefully monitored.
Floating gate power supply of multilevel converters for circuit integration (2009)

There is the possibility of the intrinsic elimination of harmonics and electromagnetic interference (EMI) by introducing multilevel converters with a large number of levels. As the number of levels increases, the number of the main switching devices on their higher side increases, and their floating gate power supplies become larger scale circuits. Because it is necessary to integrate the floating gate power supplies from the practical viewpoint, it is one of the important issues to realize the floating gate power supplies, which consist of the components suitable for the integration. In this paper, bootstrap circuits, charge pump circuits, and self power supply circuits, already proposed for the conventional 2-level converters, are extended to the floating gate power supplies for the multilevel converters: diode-clamped converters, flying capacitor converters, and series-connected H-bridge converters. The theoretical and experimental investigations of the floating gate power supplies for the multilevel converters considering the main circuit topology and the main circuit control are shown. From these results, the applicability and the required modification of the floating gate power supply methods are clarified.
Rasagiline: an anti-Parkinson drug with neuroprotective activity (2003)

Mitochondria are now recognized as potent integrators and co-ordinators of cell survival/death and apoptosis. Therefore, they are pharmacological targets for induction or correction of excessive cell death in human pathology, which includes cancer and the neurodegenerative disorders Parkinson's and Alzheimer's disease. One such agent is the anti-Parkinson drug, rasagiline, a novel neuroprotective-antiapoptotic second-generation potent irreversible selective inhibitor of monoamine oxidase B. It prevents the neurotoxin-initiated demise of mitochondria via modulation of cell survival/death Bcl-2 family proteins, Bcl-2-Bax, at the mitochondria permeability transition pore, which regulates voltage-dependent anion channels. It may also induce long-term potentiation - a consequence of its protein kinase C-dependent mitogen-activated protein kinase pathway activation. Rasagiline, unlike selegiline, is devoid of sympathomimetic action and is not metabolized to neurotoxic methamphetamine, but to aminoindan. Its neuroprotective activity is attributed to the aminoindan and propargylamine moieties and structural resemblance to certain metabotrophic glutamate 1 receptor antagonists. Ragagiline has been chosen for neuroprotective studies by the National Institutes of Health as a possible disease-modifying agent.
Supplementary Figure from The Interaction of SWI/SNF with the Ribosome Regulates Translation and Confers Sensitivity to Translation Pathway Inhibitors in Cancers with Complex Perturbations (2023)

Supplementary Figure from The Interaction of SWI/SNF with the Ribosome Regulates Translation and Confers Sensitivity to Translation Pathway Inhibitors in Cancers with Complex Perturbations
The boson peak of silicate glasses: The role of Si–O, Al–O, and Si–N bonds (2010)

The role of Si-O, Al-O, and Si-N bonds on the boson peak of silicate glasses has been investigated from a study of amorphous Si, SiO(2), and two calcium aluminosilicates with 0 (Ca28-O) and 4.4 (Ca28-N) mol % Si(3)N(4). The low-frequency part of the vibrational density of states g(omega) has been calculated from inversion of literature data and new heat capacity measurements. As defined by g(omega)/omega(2), the boson peak correlates with the excess heat capacity observed with respect to Debye T(3) limiting law. That libration of SiO(4) tetrahedra represents the main source of low-frequency excitations in silica glass is illustrated by the strong difference between the anomalies of amorphous Si and SiO(2) glass and the marked decrease observed for SiO(2) phases of increasing density. When Al substitutes for Si, libration of AlO(4) tetrahedra appears hampered by the presence of a charge-compensating cation. Rigidification of the silicate network resulting from substitution of N for O causes the boson peak of Ca28-N to be smaller than that of Ca28-O and shifted toward higher frequencies as increased cross-linking hinders libration of SiO(4) or AlO(4) tetrahedra. In agreement with their universal phenomenology, the calorimetric boson anomalies of Ca28-O and Ca28-N plot on the master curve defined previously by SiO(2) and alkali silicate glasses.
Areas of brain activation in males and females during viewing of erotic film excerpts (2002)

Abstract Various lines of evidence indicate that men generally experience greater sexual arousal (SA) to erotic stimuli than women. Yet, little is known regarding the neurobiological processes underlying such a gender difference. To investigate this issue, functional magnetic resonance imaging was used to compare the neural correlates of SA in 20 male and 20 female subjects. Brain activity was measured while male and female subjects were viewing erotic film excerpts. Results showed that the level of perceived SA was significantly higher in male than in female subjects. When compared to viewing emotionally neutral film excerpts, viewing erotic film excerpts was associated, for both genders, with bilateral blood oxygen level dependant (BOLD) signal increases in the anterior cingulate, medial prefrontal, orbitofrontal, insular, and occipitotemporal cortices, as well as in the amygdala and the ventral striatum. Only for the group of male subjects was there evidence of a significant activation of the thalamus and hypothalamus, a sexually dimorphic area of the brain known to play a pivotal role in physiological arousal and sexual behavior. When directly compared between genders, hypothalamic activation was found to be significantly greater in male subjects. Furthermore, for male subjects only, the magnitude of hypothalamic activation was positively correlated with reported levels of SA. These findings reveal the existence of similarities and dissimilarities in the way the brain of both genders responds to erotic stimuli. They further suggest that the greater SA generally experienced by men, when viewing erotica, may be related to the functional gender difference found here with respect to the hypothalamus. Hum. Brain Mapping 16:1–13, 2002. © 2002 Wiley‐Liss, Inc.
Pneumonia: The Impact of Antibiotic Resistance on Its Management (1995)

Pneumonia in the community affects between 1 and 5 per 1000 per year. The microbial aetiology is diverse and influenced by preexisting disease, seasonality, as well as animate and inanimate environmental sources; pneumococci, Legionella spp., Mycoplasma pneumoniae, and more recently Chlamydia pneumoniae are the predominant bacterial pathogens. Gram-negative enteric bacteria although less common are particularly virulent. Antibiotic resistance is well established for Haemophilus influenzae and Gram-negative bacillary infections, but has been a recent phenomenon in the case of Streptococcus pneumoniae, which is numerically the leading pathogen. Despite the concerns raised by this reduced susceptibility to penicillin, evidence that this has been translated into increased clinical failures is currently difficult to establish. Macrolide and tetracycline resistance among pneumococci is more common. beta-Lactamase production by H. influenzae has now reached levels where, in those with severe pneumonia, beta-lactamase stable agents are preferred. Consensus Guidelines on the treatment of community acquired pneumonia have been published by the British Thoracic Society, the American Thoracic Society, and from Expert Panels in Canada and France. These emphasize severity assessment and differentiate management in the community or hospital setting. The recommended regimens are compared and contrasted. In conclusion, mild/moderate pneumonia, when pneumococcal in nature, is likely to still respond to amoxycillin or penicillin G, but in higher dosages where pneumococcal resistance is documented. However, in severe infection where pneumococcal resistance, other beta-lactamase-producing pathogens, or an atypical infection could be operating, it is important that initial empirical therapy be broad spectrum and promptly administered. Treating multiresistant pneumococcal disease in those allergic to beta-lactams presents a particular dilemma. Glycopeptides are currently preferred.
Ultra-high-sensitivity 3D-printed FBG-based pressure sensor (2018)

An optical fiber sensor for the measurement of pressure is presented and experimentally characterized. The sensor, produced by additive manufacturing, converts pressure variations into strain along a fiber Bragg grating, and reaches the remarkable sensitivity of 25 pm/mbar at 1550 nm.
Effects of Antenatal Glucocorticoid Therapy on Hippocampal Histology of Preterm Infants (2012)

We found a significantly lower density of neurons in the hippocampus of neonates after antenatal glucocorticoid treatment. Although the pathophysiological and clinical interpretations of these findings are not clear, they are consistent with those from experiments in mice and rhesus monkeys.
Mutual coupling reduction of dual-frequency patch antenna arrays (2015)

In this paper, a compact patch antenna array with dual resonant frequencies is presented. The mutual coupling between array elements can be reduced simultaneously at two frequencies by inserting a simple C-shaped split ring resonator (SRR) between the radiating patches and etching a rectangular split ring slot defected ground structure (DGS) on the ground plane. The simulated results show that the mutual coupling between array elements has a reduction of about 10 dB and 17 dB at the two operating frequencies. Details of the antenna design and results are presented and discussed.
A real-time model of retinal stimulation in virtual environments (2020)

The experimental control granted by virtual reality (VR) allows investigation of complex behaviors involving naturalistic stimuli. VR engines provide direct access to the images viewed by subjects, facilitating analyses of image properties that are often difficult to extract from real scenes. For example, current computer vision algorithms of optic flow are often inaccurate in complex scenes with significant depth variations. We have developed a prototypical model of the eye to allow for real-time recording of visual stimuli projected onto the retina from the virtual environment. The Panfili Functional Eye (PFE) model uses real-time ray tracing to compute the optic flow stimuli rendered by the VR engine. The PFE uses a pinhole model of the eye with refraction, with input parameters designating resolution, field of view, and movement method. An array of virtual photoreceptors is generated along the surface of a virtual retina. The virtual photoreceptors cast rays through the pupil, where refraction is applied using Snell’s Law. These rays are then cast out to the virtual environment, returning information such as world position, normal of the vector, and coordinates on the UV/Lightmap of the object. The primary goal of the model is to describe the geometric projection of the virtual environment onto the retina in real-time. High-fidelity and low-latency retinal modeling has not been previously possible due to the technical limitations of ray tracing. The model performs as much as 150 times faster than comparable methods, a metric which should increase exponentially with the use of parallel processing. The PFE is modular to allow for the incorporation of more complex optical models, simulating eye conditions, and the analysis of other visual features. Our current application uses the model to compute optic flow patterns of experimental stimuli contingent on direction of gaze while subjects walk freely in a virtual environment.
Ein einfaches Verfahren zur Darstellung von α‐Alkyl‐benzoinen und α‐Alkyl‐benzoinalkyläthern (1970)

Abstract Benzoin (1) wird in Dimethylsulfoxid bei 25° unter Zusatz von Natronlauge mit Alkyl‐halogeniden schonend alkyliert. Das Verhältnis der hierbei gebildeten α‐Alkyl‐benzoine und Benzoinalkyläther nimmt in der Reihe Alkyl‐jodid, ‐bromid, ‐chlorid und ‐tosylat ab. Mit äquimolaren Mengen Alkyljodid reagiert 1 zu α‐Alkyl‐benzoinen, mit einem Überschuß zu α‐Alkylbenzoinalkyläthern. Diese entstehen ebenfalls bei der Alkylierung von Benzoinalkyläthern mit Alkyljodiden bzw. von α‐Alkyl‐benzoinen mit Alkylhalogeniden oder ‐sulfonaten in guten Ausbeuten. Mit Allyl‐ und Benzylchlorid wird 1 nur C‐alkyliert. Diese Selektivität laßt sich zur Darstellung von α‐Alkyl‐benzoinalkyläthern mit verschiedenen Alkyl‐Substituenten aus 1 in einer Eintopfreaktion nutzen.