gebhart/patrepeval huggingface dataset:
Selective Conversion of CO2 to CO with High Efficiency Using an Inexpensive Bismuth-Based Electrocatalyst (2013)

The wide-scale implementation of solar and other renewable sources of electricity requires improved means for energy storage. An intriguing strategy in this regard is the reduction of CO2 to CO, which generates an energy-rich commodity chemical that can be coupled to liquid fuel production. In this work, we report an inexpensive bismuth-carbon monoxide evolving catalyst (Bi-CMEC) that can be formed upon cathodic polarization of an inert glassy carbon electrode in acidic solutions containing Bi(3+) ions. This catalyst can be used in conjunction with ionic liquids to effect the electrocatalytic conversion of CO2 to CO with appreciable current density at overpotentials below 0.2 V. Bi-CMEC is selective for production of CO, operating with a Faradaic efficiency of approximately 95%. When taken together, these correspond to a high-energy efficiency for CO production, on par with that which has historically only been observed using expensive silver and gold cathodes.
Very Slow Intramolecular Vibrational Energy Redistribution (IVR) for Molecules in Planar Conformations (2001)

Evidence is presented that shows very slow intramolecular energy redistribution (IVR) in the acetylenic C−H stretch fundamental of molecules in planar conformations. Each molecule,4-chlorobut-1-yne, 4-bromobut-1-yne, 4-fluorobut-1-yne, methyl propargyl ether, 1-pentyne, and pent-1-en-4-yne have a planar trans conformer (except for pent-1-en-4-yne where the planar conformer is cis) that is connected to a nonplanar gauche (skew) conformer by rotation about a C−C bond (C−O for methyl propargyl ether). The planar forms (observed for each molecule except methyl propargyl ether) of these molecules exhibit some of the slowest hydride stretch IVR rates measured, with τIVR for the acetylenic C−H stretch ranging from 1 to 3 ns. These results are compared to the IVR lifetimes for the nonplanar conformers of 1-pentyne and methyl propargyl ether (τIVR ≈ 300 ps). Also presented are a series of molecules ((Z)-pent-3-en-1-yne, (E)-pent-3-en-1-yne, 1-butyne, 3-fluorobut-1-yne, and 2-methyl-1-buten-3-yne) that have a single methyl group substituent and do not form different conformations upon rotation about the C−C bond. The barrier to internal rotation of the methyl tops range from 389 to 2016 cm-1; however, the IVR lifetimes of the acetylenic C−H stretch for each is near 100 ps.
Direct Probing of Sorbent−Solvent Interactions for Amylose Tris(3,5-dimethylphenylcarbamate) Using Infrared Spectroscopy, X-ray Diffraction, Solid-state NMR, and DFT Modeling (2006)

The sorbent-solvent interactions for amylose tris(3, 5-dimethylphenylcarbamate) (ADMPC) with five commonly used solvents, hexane, methanol, ethanol, 2-propanol (IPA), and acetonitrile (ACN), are studied using attenuated total reflection infrared spectroscopy (ATR-IR) of thin sorbent films, X-ray diffraction (XRD) of thin films, (13)C cross polarization/magic angle spinning (CP/MAS) and MAS solid state NMR of polymer-coated silica beads (commercially termed "Chiralpak AD"), and DFT modeling. The ADMPC-polymer-coated silica beads are used commercially for analytical and preparative scale separations of chiral enantiomers. The polymer forms helical rods with intra- and inter-rod hydrogen bonds (H-bonds). There are various nm-sized cavities formed between the polymer side-chains and rods. The changes in the H-bonding states of the C=O and NH groups of the polymer upon absorption of each of the five solvents at 25 degrees C are determined with ATR-IR. The IR wavenumbers, the H-bonding interaction energies, and the H-bonding distances of the polymer side-chains with each of the solvent molecules are predicted using the DFT/B3LYP/6-311+g(d,p) level of theory. The changes in the polymer crystallinity upon absorption of each solvent are characterized with XRD. The changes in the polymer crystallinity and the H-bonding states of C=O groups are also probed with (13)C CP/MAS solid-state NMR. The changes in the polymer side-chain mobility are detected using (13)C MAS solid-state NMR. The H-bonding states of the polymer change upon absorption of each polar solvent and usually result in an increase in the polymer crystallinity and the side-chain mobility. The polymer rods are reorganized upon solvent absorption, and the distance between the rods increases with the increase in the solvent molecular size. These results have implications for understanding the role of the solvent in modifying the structure and behavior of the polymer sorbents.
1998: Time sections of frontal passages seen in the MST radar signal compared with ozone data (1997)

International audience
Removal of Dyes from Wastewater Using Flyash, a Low-Cost Adsorbent (2002)

The use of low-cost adsorbent has been investigated as a replacement for the current expensive methods of removing dyes from wastewater. As such, fly ash generated in National Thermal Power plant was collected and converted into a low-cost adsorbent. The prepared adsorbent was characterized and used for the removal of dyes from wastewater. Adsorption studies were carried out for different temperatures, particle sizes, pH's, and adsorbent doses. The adsorption of each dye was found to increase with increasing temperature, thereby indicating that the process is endothermic in nature. The removal of each dye was found to be inversely proportional to the size of the fly ash particles, as expected. Both the linear and nonlinear forms of the Langmuir and Freundlich models fitted the adsorption data. The results indicate that the Freundlich adsorption isotherm fitted the data better than the Langmuir adsorption isotherm. Further, the data were better correlated with the nonlinear than the linear form of this equation. Thermodynamic parameters such as the free energies, enthalpies, and entropies of adsorption of the dye−fly ash systems were also evaluated. The negative values of free energy indicate the feasibility and spontaneous nature of the process, and the positive heats of enthalpy suggest the endothermic nature of the process. The adsorptions of crystal violet and basic fuschin follow first-order rate kinetics. In comparison to other low-cost adsorbents, the sorption capacity of the material under investigation is found to be comparable to that of other commercially available adsorbents used for the removal of cationic dyes from wastewater.
An SDN‐based scalable routing and resource management model for service provider networks (2018)

Summary Volume of the Internet traffic has increased significantly in recent years. Service providers (SPs) are now striving to make resource management and considering dynamically changing large volume of network traffic. In this context, software defined networking (SDN) has been alluring the attention of SPs, as it provides virtualization, programmability, ease of management, and so on. Yet severe scalability issues are one of the key challenges of the SDN due to its centralized architecture. First of all, SDN controller may become the bottleneck as the number of flows and switches increase. It is because routing and admission control decisions are made per flow basis by the controller. Second, there is a signaling overhead between the controller and switches since the controller makes decisions on behalf of them. In line with the aforementioned explanations, this paper proposes an SDN‐based scalable routing and resource management model (SRRM) for SPs. The proposed model is twofold. SRRM performs routing, admission control, and signaling operations (RASOs) in a scalable manner. Additionally, resource management has also been accomplished to increase link use. To achieve high degree of scalability and resource use, pre‐established paths (PEPs) between each edge node in the domain are provided. The proposed controller performs RASOs based on PEPs. The controller also balances the load of PEPs and adjusts their path capacities dynamically to increase resource use. Experimental results show that SRRM can successfully perform RASOs in a scalable way and also increase link use even under heavy traffic loads.
Tempest: Towards early identification of failure-prone binaries (2008)

Early estimates of failure-proneness can be used to help inform decisions on testing, refactoring, design rework etc. Often such early estimates are based on code metrics like churn and complexity. But such estimates of software quality rarely make their way into a mainstream tool and find industrial deployment. In this paper we discuss about the Tempest tool that uses statistical failure-proneness models based on code complexity and churn metrics across the Microsoft Windows code base to identify failure-prone binaries early in the development process. We also present the tool architecture and its usage as of date at Microsoft.
Epitope Mapping of the Brucella melitensis BP26 Immunogenic Protein: Usefulness for Diagnosis of Sheep Brucellosis (2003)

Sequencing of bp26, the gene encoding the Brucella sp. immunogenic BP26 periplasmic protein, was performed in the reference strains of Brucella abortus, B. suis, and B. ovis. The three bp26 sequences were almost identical to that published for B. melitensis 16M bp26, and only minor nucleotide substitutions, without modifying the amino acid sequence, were observed between species. The bp26 genes of the seven B. abortus biovar reference strains and B. abortus S19 and RB51 vaccine strains were also sequenced. Again, only minor differences were found. Surprisingly, the bp26 nucleotide sequence for B. abortus S19 was almost identical to that found for B. melitensis 16M and differed from the sequence described previously by others (O. L. Rossetti, A. I. Arese, M. L. Boschiroli, and S. L. Cravero, J. Clin. Microbiol. 34:165-169, 1996) for the same B. abortus strain. The epitope mapping of BP26, performed by using a panel of monoclonal antibodies and recombinant DNA techniques, allowed the identification of an immunodominant region of the protein interesting for the diagnosis of B. melitensis and B. ovis infection in sheep. A recombinant fusion protein containing this region of BP26 reacted indeed, in Western blotting, as the entire recombinant BP26 against sera from B. melitensis- or B. ovis-infected sheep while it avoided false-positive reactions observed with sera from Brucella-free sheep when using the entire recombinant BP26. Thus, use of this recombinant fusion protein instead the entire recombinant BP26 could improve the specific serological diagnosis of B. melitensis or B. ovis infection in sheep.
Do Dietary Antioxidants Alleviate the Cost of Immune Activation? An Experiment with Greenfinches (2007)

Reactive oxygen and nitrogen species produced by metabolism and immune defenses can cause extensive damage to biomolecules. To counteract this damage, organisms rely on exogenous and endogenous antioxidants, although their relative importance in maintaining redox balance is unclear. We supplemented captive greenfinches with dietary antioxidants—carotenoids and vitamin E—and injected them with an inflammatory agent, phytohemagglutinin. Compared to controls, immune‐challenged birds circulated more lipid peroxidation products but also increased total plasma antioxidativity. Carotenoid (but not vitamin E) supplementation generally reduced lipid peroxidation, but this did not compensate for the effects of immune activation. Levels of an endogenous antioxidant—uric acid—strongly contributed to plasma antioxidativity. We found no evidence that dietary antioxidants are immunostimulatory. These results demonstrate the antioxidant function of carotenoids in birds and show that simultaneous assessment of oxidative stress‐driven damage, antioxidant barrier, and individual antioxidants is critical for explaining the potential costs of immune system activation.
Probiotics Stimulate Production of Natural Antibodies in Chickens (2006)

Commensal bacteria in the intestine play an important role in the development of immune response. These bacteria interact with cells of the gut-associated lymphoid tissues (GALT). Among cells of the GALT, B-1 cells are of note. These cells are involved in the production of natural antibodies. In the present study, we determined whether manipulation of the intestinal microbiota by administration of probiotics, which we had previously shown to enhance specific systemic antibody response, could affect the development of natural antibodies in the intestines and sera of chickens. Our findings demonstrate that when 1-day-old chicks were treated with probiotics, serum and intestinal antibodies reactive to tetanus toxoid (TT) and Clostridium perfringens alpha-toxin in addition to intestinal immunoglobulin A (IgA) reactive to bovine serum albumin (BSA) were increased in unimmunized chickens. Moreover, IgG antibodies reactive to TT were increased in the intestines of probiotic-treated chickens compared to those of untreated controls. In serum, IgG and IgM reactive to TT and alpha-toxin were increased in probiotic-treated, unimmunized chickens compared to levels in untreated controls. However, no significant difference in serum levels of IgM or IgG response to BSA was observed. These results are suggestive of the induction of natural antibodies in probiotic-treated, unimmunized chickens. Elucidating the role of these antibodies in maintenance of the chicken immune system homeostasis and immune response to pathogens requires further investigation.
Cardiac arrhythmia classification using autoregressive modeling (2002)

The results show that AR modeling is useful for the classification of cardiac arrhythmias, with reasonably high accuracies. Further validation of the proposed technique will yield acceptable results for clinical implementation.
Complex Regional Pain Syndrome: Time to Study the Supraspinal Role? (2015)

The International Association for the Study of Pain (IASP) defines complex regional pain syndrome (CRPS) as a spontaneous or stimulus-induced pain that is disproportionate to the inciting event and is accompanied by a wide variety of autonomic and motor disturbances, in highly variable combinations. As noted in the definition, there are a number of possible causes for CRPS. These include tissue damage, nerve damage, casting, traumas, fractures, burns, frostbites, strokes, and other non-identifiable causes. The symptoms of reflex sympathetic dystrophy that do not accompany nerve damage are generally classified as CRPS type 1, while those accompanying nerve damage - such as causalgia - are classified as CRPS type 2. Although various reports have suggested different incidence rates, the condition has generally been found in 20-30 cases per 100,000 persons; the incidence rate of CRPS type 2 is reported to be 0.82 cases per 100,000 persons.
Wirkung neuer Iminiumverbindungen gegen ausgewählte Bakterien‐ und Pilzstämme, 20. Mitt.: Synthese von 1‐Methyl‐2‐alkyl‐3‐(n‐alkoxymethyl)‐und 1‐Methyl‐3‐(n‐alkoxymethyl)‐5‐chlorimidazoliumchloriden (1988)

Abstract Die antimikrobiellen Eigenschaften der neuen Titelverbindungen wurden an 13 Baktieren‐und Pilz‐Stämmen geprüft: die Verbindungen 1 – 4 sind am besten antibakteriell wirksam.
A semi-automated protocol for Archaea DNA extraction from stools (2013)

Proteinase K digestion and glass powder crushing dramatically increase the extraction yield of archaea DNA from human stools. The semi-automated protocol described here was more rapid than the manual protocol and yielded significantly more archaeal DNA. It could be applied for extracting total stool DNA for further PCR amplification.
A Long Term Evaluation of the Japanese Medical Payment System for Cataract Surgeries: Did the Medical Policy Reduce the Long Hospital Stay in Japan? (2016)

In this paper, we conducted a long term survey of the cataract surgeries. The sample period was about 7 years, from July 2005 to March 2012. We evaluated the effects of three revisions of the medical payment system that were done in 2006, 2008 and 2010. For the analysis, the Box-Cox transformation model and Hausman test using Nawata’s estimator were used for the length of stay (LOS) in hospitals, and the ordinary least squares method was used for the non-inclusive (mainly payments for surgeries) payments. We analyzed a dataset of 51,054 patients obtained from 60 hospitals (Hp1-60) where more than 300 one-eye cataract surgeries were performed during the period. For the LOS, we found that only the 2008 revision had significant impact on shortening the LOS but the other two did not. We also found very large differences among hospitals even after eliminating effects of patients’ characteristics and type of principle diseases as previous studies. For non-inclusive payments 2006 and 2008 revisions had significant impacts and the differences among hospitals were much smaller than those of the LOS.
A living biosensor model to dynamically trace glucocorticoid transcriptional activity during development and adult life in zebrafish (2014)

Glucocorticoids (GCs) modulate many cellular processes through the binding of the glucocorticoid receptor (GR) to specific responsive elements located upstream of the transcription starting site or within an intron of GC target genes. Here we describe a transgenic fish line harboring a construct with nine GC-responsive elements (GREs) upstream of a reporter (EGFP) coding sequence. Transgenic fish exhibit strong fluorescence in many known GC-responsive organs. Moreover, its enhanced sensitivity allowed the discovery of novel GC-responsive tissue compartments, such as fin, eyes, and otic vesicles. Long-term persistence of transgene expression is seen during adult stages in several organs. Pharmacological and genetic analysis demonstrates that the transgenic line is highly responsive to drug administration and molecular manipulation. Moreover, reporter expression is sensitively and dynamically modulated by the photoperiod, thus proving that these fish are an in vivo valuable platform to explore GC responsiveness to both endogenous and exogenous stimuli.
Beyond maternal education: Socio-economic inequalities in children’s diet in the ABCD cohort (2020)

All socio-economic indicators were associated with increased risk of unhealthy dietary patterns in young children, with low maternal education conferring the highest risk. Yet, within the group of middle-high educated mothers, lower household finance was an extra risk factor for unhealthy dietary patterns. Intervention strategies should therefore focus on lower educated mothers and middle-high educated mothers with insufficient levels of household finance.
Inherited mutations in breast cancer genes in African American breast cancer patients revealed by targeted genomic capture and next-generation sequencing. (2013)

CRA1501 Background: African American (AA) women are disproportionately affected by early-onset and triple-negative breast cancer (TNBC). One explanation for these disparities may be a higher frequency of inherited mutations among AA women in genes in DNA repair pathways, including BRCA1 and BRCA2. Using targeted genomic capture and next generation sequencing (NGS), we screened DNA from AA women with breast cancer for mutations in all 18 known breast cancer genes. Methods: A total of 249 unrelated AA women with breast cancer were ascertained through the Cancer Risk Clinic at The University of Chicago. Genomic DNA was extracted from peripheral blood and 3 micrograms were used for targeted capture and sequencing. Average read depth across the 1.4 MB targeted region was 320-fold. Sequence reads were aligned and all classes of variants identified: point mutations, small insertions and deletions, and large genomic rearrangements. Only unambiguously damaging mutations were called: stops, complete genomic deletions, and missenses demonstrated experimentally to cause loss of protein function. Variants were validated by PCR or Taqman analysis. Results: Fifty-six of 249 subjects (22%) carried at least one loss-of-function mutation, distributed among BRCA1 (n=26), BRCA2 (n=20), CHEK2 (n=3), PALB2 (n=3), ATM (n=5), and PTEN (n=1). The majority of mutations were unique. Damaging mutations were carried by 30% of patients with TNBC, 27% of patients diagnosed at age ≤45, 49% with a second breast primary, and 30% with a family history of either breast or ovarian cancer in any close relative. Conclusions: We present the first comprehensive screen of all known breast cancer susceptibility genes among AA women using NGS. Mutation carrier frequencies are &gt;25% for major subsets of patients defined by tumor or host characteristics. These high carrier frequencies suggest the importance of screening for mutations in all breast cancer genes in all AA breast cancer patients diagnosed at a young age, with a family history, or with TNBC as a way to identify at-risk family members for life-saving interventions.
Single-Event Tolerant Flip-Flop Design in 40-nm Bulk CMOS Technology (2011)

In this paper, the radiation response of a single-event tolerant flip-flop design named the Quatro flip-flop is presented. Circuit level simulations on the flip-flop design show 1) the critical charge of the sensitive nodes to be greater than that of DICE flip-flop, 2) the number of sensitive nodes and the sensitive area to be fewer than that of DICE flip-flop. A test-chip designed and fabricated at the 40-nm bulk CMOS technology node consisting of Quatro, DICE, and standard D- flip-flops was used for heavy-ions, neutrons, and alpha particles exposures. The experimental results demonstrate superior performance of the Quatro flip-flop design over conventional DICE and D-flip-flop designs.
Max Reinhardt's recurring Dream: Hollywood, 1935 (2007)

In the first three decades of the twentieth century, the Austrian-born Max Reinhardt was one of the most respected and internationally influential European theatre directors, renowned for productions that embraced popular and ‘classical’ repertoire, encompassing spectacle on a grand scale and intimate, ‘chamber’ theatre. He was regarded as the principal exponent of Stimmungstheater (the theatre of atmosphere) and he was habitually identified as a ‘magician’. Reinhardt's dealings as a director with A Midsummer Night's Dream began in Berlin at the Neues Theater in 1905 and ended in the United States three decades later, with the film he co-directed for Warner Bros. with William Dieterle. In the course of those years he had staged the play more than a dozen times, in many kinds of space indoors and out, from the Boboli Gardens in Florence to the Hollywood Bowl. He often returned to plays, reworking them for new theatres and audiences, but like The Miracle, Faust and Jedermann, this was a play that Reinhardt obsessively revisited throughout his career. Lady Diana Cooper, who played both the erring nun and the Madonna in revivals of The Miracle (sometimes both on the same night), observed that he was ‘too rich in invention to tolerate satisfaction’.
Optical beam forming of MM-wave array antennas in a 60 GHz radio over fiber system (2003)

We report on new results of a novel silica based signal processor for optical beam forming in wireless communication smart antenna systems. Basic components and measurements of an envisaged 60 GHz transmission system are described.
Single walled carbon nanotubes for transport and delivery of biological cargos (2006)

Abstract The innate ability of carbon nanotubes to breach the cell membrane of various types of mammalian cells has been reported. Here, we present a summary of the various applications of carbon nanotubes as a cellular transport and delivery system for functional biological cargos. The internalization of SWNTs for transport and delivery into cells is mediated via endocytosis and does not appear to have any detrimental effect on either the transported cargo or the breached cell. The emergence of SWNT as a new class of cellular transporters holds many exciting promises for SWNT‐based systems for drug delivery, protein delivery, gene therapy and cancer therapy applications. (© 2006 WILEY‐VCH Verlag GmbH &amp; Co. KGaA, Weinheim)