gebhart/patrepeval huggingface dataset:
Gas-partitioning approach for laboratory and field studies of mirex fugacity in water (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGas-partitioning approach for laboratory and field studies of mirex fugacity in waterChengqing. Yin and John P. HassettCite this: Environ. Sci. Technol. 1986, 20, 12, 1213–1217Publication Date (Print):December 1, 1986Publication History Published online1 May 2002Published inissue 1 December 1986https://pubs.acs.org/doi/10.1021/es00154a003https://doi.org/10.1021/es00154a003research-articleACS PublicationsRequest reuse permissionsArticle Views168Altmetric-Citations66LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Perceptual quality prediction on authentically distorted images using a bag of features approach (2017)

Current top-performing blind perceptual image quality prediction models are generally trained on legacy databases of human quality opinion scores on synthetically distorted images. Therefore, they learn image features that effectively predict human visual quality judgments of inauthentic and usually isolated (single) distortions. However, real-world images usually contain complex composite mixtures of multiple distortions. We study the perceptually relevant natural scene statistics of such authentically distorted images in different color spaces and transform domains. We propose a "bag of feature maps" approach that avoids assumptions about the type of distortion(s) contained in an image and instead focuses on capturing consistencies-or departures therefrom-of the statistics of real-world images. Using a large database of authentically distorted images, human opinions of them, and bags of features computed on them, we train a regressor to conduct image quality prediction. We demonstrate the competence of the features toward improving automatic perceptual quality prediction by testing a learned algorithm using them on a benchmark legacy database as well as on a newly introduced distortion-realistic resource called the LIVE In the Wild Image Quality Challenge Database. We extensively evaluate the perceptual quality prediction model and algorithm and show that it is able to achieve good-quality prediction power that is better than other leading models.
INFECTION IMAGING BY USING LIPOSOMES LABELED WITH TWO RADIONUCLIDES-Tc-99m and In-111 (DUAL RADIOLABELED LIPOSOMES). (1997)

Phillips, W. T.; Awasthi, V. D.; Goins, B.; Klipper, R.; Blumhardt, R. Author Information
Biochemical and molecular effects of chronic haloperidol administration on brain and muscle mitochondria of rats (1998)

The objectives of the current study were to evaluate (1) the respiratory rates and enzyme activities of brain and muscle mitochondria from rats chronically treated with haloperidol, (2) the protective role of dopamine (DA) D-1 (SKF38393) and D-2 (quinpirole) receptor agonists, and (3) the effect of haloperidol on the mitochondrial DNA (mtDNA) and protein synthesis. Thirty male Sprague-Dawley rats were subdivided into the following five groups: controls, haloperidol, haloperidol plus SKF38393, haloperidol plus quinpirole, and haloperidol plus SKF38393 and quinpirole. We compared the respiratory rates and enzymatic activities of brain and muscle mitochondria from controls with other groups. We finally analyzed the mitochondrial protein synthesis and mtDNA alterations (deletions, point mutations, and depletion) in two rats from each group. In brain but not in muscle from haloperidol-treated rats, we found a decrease of oxygen consumption rates using glutamate plus malate (−68 ± 35%, P < 0.05) and succinate (−78 ± 20%, P < 0.05) as substrates as well as low complex I, II, and V activities (−35 ± 15%, P < 0.05; −54 ± 13%, P < 0.05; and −60 ± 33%, P < 0.01; respectively). The administration of SKF38393 alone or together with quinpirole prevented most of haloperidol-induced effects, whereas the protective effects of quinpirole alone were lower. Brain mitochondrial protein synthesis was decreased in haloperidol-treated rats and was not prevented by SKF38393, quinpirole, or both. We did not find mtDNA abnormalities in brain or muscle mitochondria from haloperidol-treated rats. Chronic administration of haloperidol in rats is associated with a nonspecific deleterious effect in the activity of electron transport chain of brain, and this effect is only partially prevented by DA D-1 agonists. These results suggest that other mechanisms different from DA receptors pathway can contribute to the expression of behavioral supersensitivity. J. Neurosci. Res. 53:475–481, 1998. © 1998 Wiley-Liss, Inc.
A pilot study of tele-ophthalmology outreach services to primary care (1998)

We have begun a randomized study of tele-ophthalmology. General practitioners in two participating health centres in the Negev region of Israel, serving a local population of 40,000, were invited to participate. The study group consisted of 50 consecutive patients attending the general eye outpatient clinic and 50 consecutive patients suffering from various retinal diseases attending a hospital outpatient clinic. The initial assessment was carried out via the tele-ophthalmology system. There was then a face-to-face re-examination of the same patients, in randomized order, by the same ophthalmologist on the same day, at an outpatient ophthalmology clinic.
Are interface theories equivalent to contract theories? (2014)

Contract-based design is emerging as a unifying compositional paradigm for the specification, design and verification of large-scale complex systems. Different contract frameworks are currently available, but we lack a clear understanding of the relations between them. In this paper, we investigate the relation between interface theories (specifically, relational interfaces) and assume-guarantee (A/G) contracts. We introduce a natural transformation of interfaces to A/G contracts represented by linear temporal logic. Then, we analyze differences and correspondences between key operators and relations in the two theories (i.e. composition, refinement and conjunction), by studying their preservation properties under the proposed transformation. We show that the transformation preserves refinement, but does not generally preserve serial composition and conjunction. Then, we present an assumption-projection operator to make it possible to preserve serial composition and compatibility checking. Finally, we provide illustrative examples that shed light on the effectiveness of both frameworks for requirement formalization, early detection of integration errors, and use of abstraction-refinement.
Iridium‐Catalysed Asymmetric Hydrogenation of Vinylsilanes as a Route to Optically Active Silanes (2006)

Abstract The first use of vinylsilanes as substrates in the asymmetric iridium‐catalysed hydrogenation is reported, providing products with enantioselectivities of up to 98 %.
In vitro Activities of Cationic Steroid Antibiotics, CSA-13, CSA-131, CSA-138, CSA-142 and CSA-192 against carbapenem-resistant Pseudomonas aeruginosa (2018)

Pseudomonas aeruginosa is one of the important opportunistic pathogen that is difficult to treat because of the antibiotic resistance developed in recent years. Developing carbapenem-resistance led to an increase in hospital infections caused by this bacterium. As a result, researchers began to search for new molecules. Ceragenins are the general name of membrane-acting cationic steroid antimicrobial molecules that have activity similar to antimicrobial peptides. In this study, we investigated the in vitro activities of cationic steroid antibiotics (CSA's) CSA-13, CSA-131, CSA-138, CSA-142, CSA-192 and colistin on carbapenem-resistant P. aeruginosa (CRPA). METHODS: MICs and MBCs were determined by broth dilution method. RESULTS: MIC50 (g / ml) values of CSA-13, CSA-131, CSA-138, CSA-142, CSA-192, colistin and meropenem are 8, 4, 8, 16, 32, 1 and 16 respectively. The MBC values were equal to or twice the MIC values. DISCUSSION AND CONCLUSION: In conclusion, we think CSA-131 and CSA-138 will be good candidates for CRPA treatment. However, the lack of stability, efficacy and pharmacokinetic properties of CSA requires further research in the future in vivo and in vitro.
Production of 1,3-propanediol from glycerol by engineered using a novel coexpression vector (2009)

1,3-Propanediol (1,3-PD) has versatile applications in polymers, cosmetics, foods and medicines. In order to consolidate the functions of glycerol dehydratase gene dhaB and 1,3-propanediol oxidoreductase gene dhaT and produce 1,3-PD from glycerol, the genes dhaB and dhaT from Klebsiella pneumoniae were inserted into a co-expression vector pACYCDuet-1 synchronously and the recombinant strain E. coli/pACYCDuet-dhaB-dhaT was obtained. Both enzymes were functionally coexpressed in E. coli at the presence of the selective pressure and the addition of the IPTG. The specific enzyme activity of DHAB and DHAT were 8.3 and 6.2 U/mg, respectively. When cultivated at 37°C for 30 h, the recombinant microorganisms produced 1,3-PD of 11.3 g with the consumption of 40 g glycerol per liter. The production of 1,3-PD by the strain E. coli/pACYCDuet-dhaB-dhaT was about 13-fold higher than the recombinant E. coli harboring the gene dhaB.
Building a Test Suite for Web Application Scanners (2008)

This paper describes the design of a test suite for thorough evaluation of web application scanners. Web application scanners are automated, black-box testing tools that examine web applications for security vulnerabilities. For several common vulnerability types, we classify defense mechanisms that can be implemented to prevent corresponding attacks. We combine the defense mechanisms into "levels of defense" of increasing strength. This approach allows us to develop an extensive test suite that can be easily configured to switch on and off vulnerability types and select a level of defense. We evaluate the test suite experimentally using several web application scanners, both open-source and proprietary. The experiments suggest that the test suite is effective at distinguishing the tools based on their vulnerability detection rate; in addition, its use can suggest areas for tool improvement.
Enhanced Immunostimulating Activity of Lactobacilli-Mimicking Materials by Controlling Size (2015)

The design and synthesis of materials capable of activating the immune system in a safe manner is of great interest in immunology and related fields. Lactobacilli activate the innate immune system of a host when acting as probiotics. Here, we constructed lactobacilli-mimicking materials in which polysaccharide-peptidoglycan complexes (PS-PGs) derived from lactobacilli were covalently conjugated to the surfaces of polymeric microparticles with a wide variety of sizes, ranging from 200 nm to 3 μm. The artificial lactobacilli successfully stimulated macrophages without cytotoxicity. Importantly, we found that the size of artificial lactobacilli strongly influenced their immunostimulating activities, and that artificial lactobacilli of 1 μm exhibited 10-fold higher activity than natural lactobacilli. One major advantage of the artificial lactobacilli is facile control of size, which cannot be changed in natural lactobacilli. These findings provide new insights into the design of materials for immunology as well as the molecular biology of lactobacillus.
Dopamine-induced Endocytosis of Na+,K+-ATPase Is Initiated by Phosphorylation of Ser-18 in the Rat α Subunit and Is Responsible for the Decreased Activity in Epithelial Cells (1999)

Dopamine inhibits Na+,K+-ATPase activity in renal tubule cells. This inhibition is associated with phosphorylation and internalization of the alpha subunit, both events being protein kinase C-dependent. Studies of purified preparations, fusion proteins with site-directed mutagenesis, and heterologous expression systems have identified two major protein kinase C phosphorylation residues (Ser-11 and Ser-18) in the rat alpha1 subunit isoform. To identify the phosphorylation site(s) that mediates endocytosis of the subunit in response to dopamine, we have performed site-directed mutagenesis of these residues in the rat alpha1 subunit and expressed the mutated forms in a renal epithelial cell line. Dopamine inhibited Na+,K+-ATPase activity and increased alpha subunit phosphorylation and clathrin-dependent endocytosis into endosomes in cells expressing the wild type alpha1 subunit or the S11A alpha1 mutant, and both effects were blocked by protein kinase C inhibition. In contrast, dopamine did not elicit any of these effects in cells expressing the S18A alpha1 mutant. While Ser-18 phosphorylation is necessary for endocytosis, it does not affect per se the enzymatic activity: preventing endocytosis with wortmannin or LY294009 blocked the inhibitory effect of dopamine on Na+,K+-ATPase activity, although it did not alter the increased alpha subunit phosphorylation induced by this agonist. We conclude that dopamine-induced inhibition of Na+, K+-ATPase activity in rat renal tubule cells requires endocytosis of the alpha subunit into defined intracellular compartments and that phosphorylation of Ser-18 is essential for this process.
Plantae Papuanae Archboldianae, IX (1942)

Tills paper covers the Myrlaceae (excludinf^; Ortamyrtus Diels, and a few incomplete specimens) of the Archbold Expeditions' collections not included in Mr. C. V. White's [xiper published in the last issue of this Journal, which was larj^ely limited to a consideration of those genera characterized by having dry dehiscent fruits.Our work has been greatly handicai)[)ed owing to the unavailability of ty])e-materia], the consequent necessity of making our determinations from descri[)tions alone, and the large number of species already re[)orted from Xew (Guinea.The genera rei)resented in these extensive and varied collections are Dcraspcrmntn, Myrtus^ Xantliomyrtus, FMgcnia, Armcna, Syzyi^ium^ and Clcistocalyx; of the latter genus only a single collection, C. Bacurrlcnii ( l\ v. Muell.)Merr.& Perry, is rep-' resented, this from the type-region.In this work, we have again learned that mature fruit is more necessary than ilowers for reasonably sure generic determination.
AQUASOL: An efficient solver for the dipolar Poisson–Boltzmann–Langevin equation (2010)

The Poisson-Boltzmann (PB) formalism is among the most popular approaches to modeling the solvation of molecules. It assumes a continuum model for water, leading to a dielectric permittivity that only depends on position in space. In contrast, the dipolar Poisson-Boltzmann-Langevin (DPBL) formalism represents the solvent as a collection of orientable dipoles with nonuniform concentration; this leads to a nonlinear permittivity function that depends both on the position and on the local electric field at that position. The differences in the assumptions underlying these two models lead to significant differences in the equations they generate. The PB equation is a second order, elliptic, nonlinear partial differential equation (PDE). Its response coefficients correspond to the dielectric permittivity and are therefore constant within each subdomain of the system considered (i.e., inside and outside of the molecules considered). While the DPBL equation is also a second order, elliptic, nonlinear PDE, its response coefficients are nonlinear functions of the electrostatic potential. Many solvers have been developed for the PB equation; to our knowledge, none of these can be directly applied to the DPBL equation. The methods they use may adapt to the difference; their implementations however are PBE specific. We adapted the PBE solver originally developed by Holst and Saied [J. Comput. Chem. 16, 337 (1995)] to the problem of solving the DPBL equation. This solver uses a truncated Newton method with a multigrid preconditioner. Numerical evidences suggest that it converges for the DPBL equation and that the convergence is superlinear. It is found however to be slow and greedy in memory requirement for problems commonly encountered in computational biology and computational chemistry. To circumvent these problems, we propose two variants, a quasi-Newton solver based on a simplified, inexact Jacobian and an iterative self-consistent solver that is based directly on the PBE solver. While both methods are not guaranteed to converge, numerical evidences suggest that they do and that their convergence is also superlinear. Both variants are significantly faster than the solver based on the exact Jacobian, with a much smaller memory footprint. All three methods have been implemented in a new code named AQUASOL, which is freely available.
A Gallium Hydride as an Oxidizing Agent: Direct Synthesis of IrV Complexes via Ga−H Bond Activation (2017)

Reactions of the β-diketiminate-stabilized gallium dihydride (Nacnac)<sup>Dipp</sup> GaH<sub>2</sub> with chelating Ir<sup>I</sup> bis(phosphine) precursors under an H<sub>2</sub> atmosphere are shown to provide a simple route to Ir<sup>V</sup> complexes stabilized by strongly σ-donating hydrides and the carbene-like (Nacnac)<sup>Dipp</sup> Ga donor. Characterization of these systems as seven-coordinate Ir<sup>V</sup> tetrahydride species is supported by single crystal X-ray and neutron diffraction, and by T<sub>1</sub> NMR measurements. By contrast related systems featuring more sterically demanding (non-chelating) ancillary ligands are better described in terms of a bis(hydride) dihydrogen [L<sub>3</sub> Ir(H)<sub>2</sub> (H<sub>2</sub> )]<sup>+</sup> formulation and a formal Ir<sup>III</sup> oxidation state.
Measurement of Plasmon Response Functions with Cross-correlation Imaging using Femtosecond Laser Dark-field Microscopy (2011)

We demonstrate an electrical-field cross-correlation imaging technique to obtain a response function of localized plasmon. Based on the measured response functions, we spatiotemporally shape the plasmon by shaping the femtosecond excitation pulses.
Inhaled heparin in cystic fibrosis (2006)

Cystic fibrosis (CF) is characterised by inspissated airway secretions and chronic endobronchial infection associated with exuberant neutrophilic inflammation. Unfractionated heparin may be mucolytic and has demonstrated a number of anti-inflammatory properties; however, further safety data are needed in these subjects who are at risk of airway bleeding. The current study aimed to assess the medium-term safety and tolerability of moderately high-dose inhaled heparin in CF adults and to explore possible in vivo mucolytic and anti-inflammatory outcomes. A randomised, double-blind, placebo-controlled crossover study of twice daily inhalation of 50,000 IU of heparin for 2 weeks was undertaken in CF adults, with a 1-week washout period. Eighteen subjects were randomised and 14 (mean+/-sd age 23+/-7.8 yrs and percentage-predicted forced expiratory volume in one second 52.1+/-15.56%) completed the study protocol. Heparin neither affected blood coagulation parameters nor resulted in any increase in adverse events. Heparin inhalation had no significant effect upon forced expiratory volume in one second, symptoms of sputum clearance or sputum inflammatory markers. The current pilot study demonstrated no evidence of improved sputum clearance with 50,000 IU of inhaled heparin given twice daily to adult cystic fibrosis subjects. However, inhaled heparin was safe and the future evaluation of larger doses over a longer period may be warranted.
Calcium sulfate solubility in organic-laden wastewater. Progress report, September 1981-December 1982 (1982)

The purpose of this investigation was to determine the solubility of calcium sulfate in wastewaters, and to examine the effect of organic constituents in wastewater and in synthetic waters on calcium sulfate solubility. The study entailed both laboratory experiments and chemical equilibria computer modeling. The calcium sulfate solubility product in a solvent-extracted, ammonia-stripped coal gasification wastewater was found to be 3.65 x 10/sup -5/ M/sup 2/; this is 45% higher than that observed in clean water. Wastewater treated further by activated carbon adsorption showed the solubility product of calcium sulfate to be 2.87 x 10/sup -5/ M/sup 2/. This is only 14% higher than that observed in clean water; this indicates that organic material removed in the adsorption process may be responsible for enhanced solubility in wastewater. Synthetic wastewaters were prepared using humic-like organic compounds, since it was believed that humic-like material accounted for a major fraction of the residual organic carbon content of solvent-extracted coal gasification wastewater. Calcium sulfate solubility in oxidized samples of resorcinol, catechol, and tannic acid showed little difference from that in clean water. In humic acid, however, the calcium sulfate solubility product was 47% higher than in clean water; this increase in solubility product wasmore » similar to that observed in pretreated wastewater, indicating that a complex organic material is responsible for the increase in solubility. These results imply that calcium and organic constituents in wastewater form a chemical complex which has the effect of increasing total calcium in solution without preciptating calcium sulfate. Thus higher levels of calcium and sulfate may be maintained in wastewaters destined for reuse in recirculating cooling waters than would be indicated by considering only inorganic chemical interactions. 51 references, 18 figures, 40 tables.« less
Comparison of Supercritical CO2-Drying, Freeze-Drying and Frying on Sensory Properties of Beetroot (2020)

The aim of this study was to compare the sensory quality and acceptance of dried ready-to-eat beetroot snacks as a result of different drying methods applied: supercritical CO<sub>2</sub>-drying (scCO<sub>2</sub>-drying), frying, and freeze-drying. Descriptive sensory analysis, quality rating (10 assessors), and consumer acceptance testing (<i>n</i> = 102) were performed. Mean overall quality scores within the range of "very good" quality were found only in non-precooked scCO<sub>2</sub>-dried samples which were characterized by typical magenta color, low level of shape and surface deformations, pronounced brittleness and crispiness, and good rehydration during mastication. The other samples were in the range of "good" quality. The pre-cooking step before scCO<sub>2</sub>-drying negatively influenced the sensory quality parameters, particularly appearance. Around 60% of tested consumers showed a preference for the fried and non-precooked scCO<sub>2</sub>-dried samples. The drivers of liking were mostly related to the characteristics of the product, which was salted, fried, and crispy, with an oily and overburnt flavor, i.e., the product most similar to commercial potato chips products. Freeze-drying had a negative effect primarily on appearance and flavor. According to the sensory evaluation conducted, direct scCO<sub>2</sub>-drying without a pre-cooking step showed itself as a promising alternative drying technology in the production of dried beetroot snacks.