gebhart/patrepeval huggingface dataset:
Second-harmonic generation in proustite with a CW CO&lt;inf&gt;2&lt;/inf&gt;laser (1972)

The possibilities for nonlinear optics in proustite have been explored in a wavelength region previously indicated as having low absorption. We used a 10-W CW CO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> laser oscillating on a single transition at 9.2-μ wavelength. The observed values for nonlinearity and absorption are, respectivley, <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">(7.9 \pm 2.0) \times 10^{-23}</tex> in MKS units and 0.29 cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-1</sup> .
ChemInform Abstract: Fe‐Catalyzed Oxidative Coupling of Heteroarenes and Methylamines. (2009)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Race/Ethnic Differences in the Associations of the Framingham Risk Factors with Carotid IMT and Cardiovascular Events (2015)

The magnitude of associations between risk factors and the presence of atherosclerotic disease differs between race/ethnic groups. These subtle, yet significant differences provide insight in the etiology of cardiovascular disease among race/ethnic groups. These insights aid the race/ethnic-specific implementation of primary prevention.
Synthesis, Surface Grafting, and Fabrication of Ultrathin Polymeric SAMFETs with High Field-Effect Mobility (2018)

Densely surface-grafted monolayer (3-4 nm) poly(3-hexylthiophene) (P3HT) brushes are prepared by click chemistry. For this, P3HT chains with alkyne end groups were synthesized and chemically coupled to a surface-immobilized self-assembled monolayer (SAM) having azide functionality in an organic field-effect transistor channel. The grafted P3HT-alkyne with a molecular weight of M<sub>n,MALDI</sub> = 11 400 g mol<sup>-1</sup> ( M<sub>n,SEC</sub> = 17 400 g mol<sup>-1</sup>) and a narrow distribution of Đ = 1.15, has the highest reported molecular weight for surface-immobilized P3HT brushes. We show the successful grafting of P3HT on the substrate surface with atomic force microscopy, contact angle, and absorption studies. From the film thickness, we can calculate the reduced tethered densities of ∑ = 10.3-12.1, which is indicative of the monolayers being in the true brush regime with high grafting density that is enough to form a compact self-assembled monolayer. The aggregation behavior of the films is characterized by UV-vis spectroscopy and compared to linear P3HT and a bottlebrush copolymer polystyrene- g-P3HT (PS- g-P3HT) with similar P3HT lengths. For such an SAM-based organic field-effect transistor (SAMFET) nanodevice with an ultrathin P3HT layer of 3-4 nm, a very high field-effect mobility of up to 1.8 × 10<sup>-3</sup> cm<sup>2</sup> V<sup>-1</sup> s<sup>-1</sup> is achieved in channel lengths of 5-20 μm, which is nearly 2 orders of magnitude higher than reported values for polymer-based SAMFETs.
A Genome-wide Association Study Identifying RAP1A as a Novel Susceptibility Gene for Crohn’s Disease in Japanese Individuals (2018)

RAP1A is a novel susceptibility locus for CD in the Japanese population.
Sclerostin Antibody Administration Increases the Numbers of Sox9creER+ Skeletal Precursors and Their Progeny (2020)

Blocking the Wnt inhibitor, sclerostin, increases the rate of bone formation in rodents and in humans. On a cellular level, the antibody against sclerostin acts by increasing osteoblast numbers partly by activating the quiescent bone-lining cells in vivo. No evidence currently exists, to determine whether blocking sclerostin affects early cells of the osteoblast lineage. Here we use a lineage-tracing strategy that uses a tamoxifen-dependent cre recombinase, driven by the Sox9 promoter to mark early cells of the osteoblast lineage. We show that, when adult mice are treated with the rat-13C7, an antibody that blocks sclerostin action in rodents, it increases the numbers of osteoblast precursors and their differentiation into mature osteoblasts in vivo. We also show that rat-13C7 administration suppresses adipogenesis by suppressing the differentiation of Sox9creER+ skeletal precursors into bone marrow adipocytes in vivo. Using floxed alleles of the CTNNB1 gene encoding β-catenin, we show that these precursor cells express the canonical Wnt signaling mediator, β-catenin, and that the actions of the rat-13C7 antibody to increase the number of early precursors is dependent on direct stimulation of Wnt signaling. The increase in osteoblast precursors and their progeny after the administration of the antibody leads to a robust suppression of apoptosis without affecting the rate of their proliferation. Thus, neutralizing the Wnt-inhibitor sclerostin increases the numbers of early cells of the osteoblast lineage osteoblasts and suppresses their differentiation into adipocytes in vivo. © 2021 American Society for Bone and Mineral Research (ASBMR).
The Use of Fine Needle Percutaneous Transhepatic Cholangiography in the Diagnosis of Jaundice in Surgical Practice (2011)

Fine needle Percutaneous Tranhepatic Cholangiography (P.T.C) was performed in series of 60 cases with suspected surgical jaundice in Surgical A unit, Hayat Shaheed Teaching Hospital, Peshawar from February 1984 to February 1990. The ductal system was successfully outlined in 57 cases with dilated intrahepatic ducts as reported on ultrasound examination in 50 cases out of 60. In two cases the ducts were not dilated on P.T.C. Mild pyrexial reaction and septicemia occurred in 57 cases (3.3%) after P.T.C Three patients developed allergic reaction to contrast medium (Biligrafin) but were resuscitated promptly. Mortality of one patient (1.6%) was recorded in this series. The patient was asthmatic and developed status asthmatic during the procedure and expired within 24 hours.
SiRNA Crosslinked Nanoparticles for the Treatment of Inflammation‐induced Liver Injury (2016)

RNA interference mediated by small interfering RNA (siRNA) provides a powerful tool for gene regulation, and has a broad potential as a promising therapeutic strategy. However, therapeutics based on siRNA have had limited clinical success due to their undesirable pharmacokinetic properties. This study presents pH-sensitive nanoparticles-based siRNA delivery systems (PNSDS), which are positive-charge-free nanocarriers, composed of siRNA chemically crosslinked with multi-armed poly(ethylene glycol) carriers via acid-labile acetal linkers. The unique siRNA crosslinked structure of PNSDS allows it to have minimal cytotoxicity, high siRNA loading efficiency, and a stimulus-responsive property that enables the selective intracellular release of siRNA in response to pH conditions. This study demonstrates that PNSDS can deliver tumor necrosis factor alpha (TNF-α) siRNA into macrophages and induce the efficient down regulation of the targeted gene in complete cell culture media. Moreover, PNSDS with mannose targeting moieties can selectively accumulate in mice liver, induce specific inhibition of macrophage TNF-α expression in vivo, and consequently protect mice from inflammation-induced liver damages. Therefore, this novel siRNA delivering platform would greatly improve the therapeutic potential of RNAi based therapies.
Profiling circulating microRNAs in the serum of pregnant and non-pregnant pigs reveals a plethora of reproductive status-dependent microRNAs (2021)

Circulating, non-coding RNAs, such as microRNAs (miRNAs) have been proposed to be powerful pathophysiological indicators of pregnancy in animals and humans. Since their discovery, it is known that miRNAs can take part in numerous biological processes, including cell proliferation and differentiation during early embryonic development and establishment of pregnancy. Our recent studies have indicated that maternal blood can carry miRNAs reported previously at the embryo-maternal interface in pigs. To expand the scope of our research, we tested the hypothesis that miRNAs previously identified in conceptuses, trophoblasts, endometrium and uterine lumen-derived extracellular vesicles (EVs) collected before Day 20 of pregnancy can show reproductive status-dependent profiles in the serum of cyclic and pregnant crossbred pigs. Custom-designed TaqMan arrays, multiplex real-time reverse transcription (RT)-PCR and real-time RT-PCR allowed us to identify a number of reproductive status-dependent miRNAs in serum samples collected from pigs during the estrous cycle or pregnancy (Days 16 and 20). We found that serum samples were enriched with miRNAs involved in processes important during the estrous cycle and early pregnancy, e.g. cell sensitivity and viability, angiogenesis, embryonic cell proliferation and differentiation. Further validation revealed different abundance of ssc-miR-143-3p and ssc-miR-125b in pregnant and non-pregnant animals and correlation of ssc-miR-125b levels with litter size. In addition, analyzed serum samples contained both EVs and Argonaute2 proteins, which are known to be involved in miRNA transportation and intercellular communication. In summary, we identified several circulating miRNAs that differ in abundance between cyclic and pregnant animals and could serve as potential indicators of reproductive status in pigs during breeding management.
Novel Automotive Engine Shaft Made of Composite with and without Material Property Grading (2021)

Abstract Engine Shafts are a very critical component of Automotive and Aerospace. Their basic purpose is to transmit power by rotation. They suppose various parts like gears and pulleys, and they are supported by bearings, which reside in the rigid machine housing. In their operation, the shafts rotate and hence they are subjected to Torsion and Bending moments. Hence, it is critical for us to choose the best material and the surface treatment process to provide optimum performance for the shaft. The primary aspects to keep into consideration while choosing a material pertaining to surface selection are Wear Resistance and Corrosion resistance. It has been shown how the selection of shaft material affects these two factors. The shafts of 3 types of materials have been discussed in the paper, a homogeneous one, a composite material, and FGM. The best material considered is FGM for the optimum operation of the automotive engine shaft.
Dentifrices for children differentially affect cell viability in vitro (2016)

The in vitro data provide the scientific foundation for further in vivo research testing the clinical relevance of the present findings.
Chronic Fatigue Syndrome and Posttraumatic Stress Disorder—Reply (2001)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Fiber-optical sensor with miniaturized probe head and nanometer accuracy based on spatially modulated low-coherence interferogram analysis (2007)

Fiber-optical sensors have some crucial advantages compared with rigid optical systems. They allow miniaturization and flexibility of system setups. Nevertheless, optical principles such as low-coherence interferometry can be realized by use of fiber optics. We developed and realized an approach for a fiber-optical sensor, which is based on the analysis of spatially modulated low-coherence interferograms. The system presented consists of three units, a miniaturized sensing probe, a broadband fiber-coupled light source, and an adapted Michelson interferometer, which is used as an optical receiver. Furthermore, the signal processing procedure, which was developed for the interferogram analysis in order to achieve nanometer measurement accuracy, is discussed. A system prototype has been validated thoroughly in different experiments. The results approve the accuracy of the sensor.
RiftNet Reconstruction Model for Radio Frequency Domain Waveform Representation and Synthesis (2021)

Waveform representation, manipulation, and synthesis are challenging problems in the RF domain traditionally demanding expert knowledge to produce transparent and efficient solutions. In this work we present a low-complexity neural network architecture for waveform representation, manipulation, and synthesis. We demonstrate this architecture's performance by training it to represent Wi-Fi 802.11a/g waveforms and modify them with the objective of enhancing waveform distinguishability for RF fingerprint classification. We further present analysis of the network waveforms' latent representation to discover time and frequency properties of the learned transform. We discuss these properties in the context of traditional signals processing transforms to increase understanding and transparency of the algorithm and inspire future research into this domain. Although we target RF domain applications, we expect this architecture's performance and benefits to have high transferability to other domains.
The effect of nanoscaffold porosity and surface chemistry on the Li-ion conductivity of LiBH4–LiNH2/metal oxide nanocomposites (2020)

Tuning the ionic conductivity of LiBH<sub>4</sub>–LiNH<sub>2</sub>/oxide nanocomposites by controlling the surface chemistry as well as the porosity of the metal oxide nanoscaffold materials.
Isolation and characterization of conditional-lethal mutations in the TUB1 alpha-tubulin gene of the yeast Saccharomyces cerevisiae. (1988)

Microtubules in yeast are functional components of the mitotic and meiotic spindles and are essential for nuclear movement during cell division and mating. We have isolated 70 conditional-lethal mutations in the TUB1 alpha-tubulin gene of the yeast Saccharomyces cerevisiae using a plasmid replacement technique. Of the 70 mutations isolated, 67 resulted in cold-sensitivity, one resulted in temperature-sensitivity, and two resulted in both. Fine-structure mapping revealed that the mutations were located throughout the TUB1 gene. We characterized the phenotypes caused by 38 of the mutations after shifts of mutants to the nonpermissive temperature. Populations of temperature-shifted mutant cells contained an excess of large-budded cells with undivided nuclei, consistent with the previously determined role of microtubules in yeast mitosis. Several of the mutants arrested growth with a sufficiently uniform morphology to indicate that TUB1 has at least one specific role in the progression of the yeast cell cycle. A number of the mutants had gross defects in microtubule assembly at the restrictive temperature, some with no microtubules and some with excess microtubules. Other mutants contained disorganized microtubules and nuclei. There were no obvious correlations between these phenotypes and the map positions of the mutations. Greater than 90% of the mutants examined were hypersensitive to the antimicrotubule drug benomyl. Mutations that suppressed the cold-sensitive phenotypes of two of the TUB1 alleles occurred in TUB2, the single structural gene specifying beta-tubulin.
Changes in leg kinematics in response to unpredictability in lateral jump execution (2014)

Lateral movements like cutting are essential in many team sport disciplines. The aim of the present study was to analyse adaptations in motor control in response to task unpredictability during lateral movement execution. Twelve subjects performed lateral jumps with different landing modalities (stable, sliding or counteracting) that were either known (predictable setting) or unknown (unpredictable setting) prior to movement execution. Results revealed that regardless of the landing modality, hip joint abduction was significantly greater in the unpredictable compared to predictable setting. Furthermore, during the sliding landing modality, hip flexion decreased from 211 ± 7° to 207 ± 7° and knee flexion decreased from 26 ± 4° to 24 ± 4° at the instant of ground contact in the unpredictable compared to predictable condition. During the stable landing modality, the knee joint abduction increased from -0.3 ± 6° to -3 ± 6° after initial ground contact in the unpredictable compared to predictable setting. The present results support our hypothesis that pre-programmed motor activity depends on the predictability of the landing modality during lateral movements. According to its adaptation in the frontal plane and in some extent in the sagittal plane, the hip joint seems to play the major role in the modulation of the pre-programmed activity for successful lateral jump execution in an unpredictable setting. However, these kinematic adaptations are concerning since these changes were associated with higher knee abduction during the stable landing modality and therefore with possible higher risk of injury.
Study on Robust Structures. 3rd Report. Design Method and Discussions on Dynamic Robust Structure Problems. (1996)

A structure with characteristics that are only slightly modified by any changes of external forces, boundary conditions, and productive errors has advantages from the engineering point of view. This kind of structure is called "robust structure". Robust structure problems are classified into the narrow sense and the broad sense. In this paper, dynamic robust structures in the broad sense are discussed. A design method of dynamic robust structures is proposed, which takes an eigenvalue as a reference function. The following three points are clarified from numerical examples of bar and plate structures. First, a dynamic robust structure can be designed when an eigenvalue is chosen as a reference function. Then a structure the mass of which is concentrated near the antinode of the vibration can gain the robustness. Finally, robust structures have advantages when the control system is designed since the optimum control gains have been only slightly affected in comparison with other designed structures.
A domain-specific approach for software development on Manycore platforms (2008)

The programming complexity of increasingly parallel processors calls for new tools that assist programmers in utilising the parallel hardware resources. In this paper we present a set of models that we have developed as part of a tool for mapping dataflow graphs onto manycores. One of the models captures the essentials of manycores identified as suitable for signal processing, and which we use as target for our algorithms. As an intermediate representation we introduce timed configuration graphs, which describe the mapping of a model of an application onto a machine model. Moreover, we show how a timed configuration graph by very simple means can be evaluated using an abstract interpretation to obtain performance feedback. This information can be used by our tool and by the programmer in order to discover improved mappings.
Two decades of policy-based storage management for the IBM mainframe computer (2003)

Today, storage management vendors see the need and business opportunity for an enterprise-wide policy-based storage management solution for their customers. In the middle 1980s, IBM introduced the Data Facility Storage Management Subsystem (DFSMS) as a policy-based storage management solution for large mainframe computer systems. As an integral part of the operating systems OS/390® and z/OS™, DFSMS continues to be enhanced. This paper provides an overview of DFSMS and describes a few of its recent enhancements.
Evidence for the widespread presence of liquid‐phase particles during the 1999–2000 Arctic winter (2002)

In situ Multiangle Spectrometer Probe (MASP) particle measurements have been analyzed to determine the typical behavior of sulfate particles during the SAGE III Ozone Loss and Validation Experiment (SOLVE) campaign. The study has explored variations in the total particle concentration measured by MASP. A new analysis method has been developed in which increases of the MASP concentration can be interpreted as growth of small particles (those which are smaller than 0.2 μm in radius at midlatitudes). The method also allows all of the MASP measurements made during the SOLVE campaign to be incorporated in a single analysis. At all levels of the stratosphere, the total MASP concentration (and therefore aerosol growth) varies continuously with temperature. This behavior is well‐reproduced by assuming that the sulfate aerosols are liquid solutions, but cannot be reproduced if the aerosol is assumed to be frozen. At sufficiently cold temperatures, larger increases in the MASP concentration are consistently seen; the observed onset temperature for this growth is in good agreement with model expectations for liquid ternary solutions. Liquid‐like behavior is apparent for all measurements made in the Arctic during SOLVE, both inside and outside the vortex, and even at the coldest temperatures sampled during the campaign. At the levels with the coldest measured temperatures, which cause maximum particle sizes and thus the greatest total MASP concentrations, 90% of the particles grow as liquids. Therefore, the freezing that occurred during the 1999–2000 Arctic winter was selective, with most of the particles remaining liquid even in the presence of a small number of frozen particles.
GaN FET's non-linear model constructed by adaptive multi-bias S-parameter measurements (2005)

The construction of a non-linear model of high frequency transistors requires S-parameter measurements at different bias points. For Gallium Nitride (GaN) based Field Effect Transistors (FETs) the safe operating area is wide, which means that the required number of bias points is very large. Consequently, the total measurement time increases to an impractical level. To reduce the total volume of experimental data and hence the measurement time, while still adequately capturing the non-linear device characteristics, a new adaptive measurement algorithm has been applied. This algorithm places more bias points in regions where the device characteristics changes rapidly and less bias points in regions where the device response stays constant. A comparison is made between S-parameter and Y-parameter based selection criteria. Finally, a GaN FET's non-linear model is constructed and good agreement is achieved between measurement and model results, verifying the proposed approach.
Dynamic detection of atomic-set-serializability violations (2008)

Previously we presented atomic sets, memory locations that share some consistency property, and units of work, code fragments that preserve consistency of atomic sets on which they are declared. We also proposed atomic-set serializability as a correctness criterion for concurrent programs, stating that units of work must be serializable for each atomic set. We showed that a set of problematic data access patterns characterize executions that are not atomic-set serializable. Our criterion subsumes data races (single-location atomic sets) and serializability (all locations in one set).