gebhart/patrepeval huggingface dataset:
Measurement of the half-life of the two-neutrino double beta decay of76Ge with the GERDA experiment (2013)

The primary goal of the GERmanium Detector Array (Gerda) experiment at the Laboratori Nazionali del Gran Sasso of INFN is the search for the neutrinoless double beta decay of Ge-76. High-purity germanium detectors made from material enriched in Ge-76 are operated directly immersed in liquid argon, allowing for a substantial reduction of the background with respect to predecessor experiments. The first 5.04 kg yr of data collected in Phase I of the experiment have been analyzed to measure the half-life of the neutrino-accompanied double beta decay of Ge-76. The observed spectrum in the energy range between 600 and 1800 keV is dominated by the double beta decay of Ge-76. The half-life extracted from Gerda data is T(1/2) = (1.84 +0.14 -0.10) 10^{21} yr.
Determination of Larger Urinary Peptides in Osteoarthrosis by High-Performance Liquid Chromatography (1986)

Urinary peptides larger than 4000 were fractionated by HPLC on reversed phase. Urines of osteoarthrotic patients were compared with those of healthy persons and rheumatoid patients. The profile of urinary peptides of patients with mild form of osteoarthrosis differed significantly from that of other groups studied. The results of patients with rheumatoid arthritis were similar to those of patients with activated or severe form of osteoarthrosis.
Detection of changes in articular cartilage proteoglycan by T1ρ magnetic resonance imaging (2004)

The purpose of this work is to demonstrate the feasibility of T(1rho)-weighted magnetic resonance imaging (MRI) to quantitatively measure changes in proteoglycan content in cartilage. The T(1rho) MRI technique was implemented in an in vivo porcine animal model with rapidly induced cytokine-mediated cartilage degeneration. Six pigs were given an intra-articular injection of recombinant porcine interleukin-1beta (IL-1beta) into the knee joint before imaging to induce changes in cartilage via matrix metalloproteinase (MMP) induction. The induction of MMPs by IL-1 was used since it has been extensively studied in many systems and is known to create conditions that mimic in part characteristics similar to those of osteoarthritis. The contralateral knee joint was given a saline injection to serve as an internal control. T(1rho)-weighted MRI was performed on a 4 T whole-body clinical scanner employing a 2D fast spin-echo-based T(1rho) imaging sequence. T(1rho) relaxation parameter maps were computed from the T(1rho)-weighted image series. The average T(1rho) relaxation rate, R(1rho) (1/T(1rho)) of the IL-1beta-treated patellae was measured to be on average 25% lower than that of saline-injected patellae indicating a loss of proteoglycan. There was an average reduction of 49% in fixed charge density, measured via sodium MRI, of the IL-1beta-treated patellae relative to control corroborating the loss of proteoglycan. The effects of IL-1beta, primarily loss of PG, were confirmed by histological and immunochemical findings. The results from this study demonstrate that R(1rho) is able to track proteoglycan content in vivo.
One for All and All for One: Distributed Learning of Fair Allocations With Multi-Player Bandits (2021)

Consider N cooperative but non-communicating players where each plays one out of M arms for T turns. Players have different utilities for each arm, represented as an N×M matrix. These utilities are unknown to the players. In each turn, players select an arm and receive a noisy observation of their utility for it. However, if any other players selected the same arm in that turn, all colliding players will receive zero utility due to the conflict. No communication between the players is possible. We propose two distributed algorithms which learn fair matchings between players and arms while minimizing the regret. We show that our first algorithm learns a max-min fairness matching with near- O(logT) regret (up to a loglogT factor). However, if one has a known target Quality of Service (QoS) (which may vary between players) then we show that our second algorithm learns a matching where all players obtain an expected reward of at least their QoS with constant regret, given that such a matching exists. In particular, if the max-min value is known, a max-min fairness matching can be learned with O(1) regret.
Processing of the native nerve growth factor precursor to form biologically active nerve growth factor. (1988)

In the mouse submaxillary gland beta nerve growth factor (beta-NGF) forms a complex with two members of the kallikrein family of serine proteases, termed the alpha- and gamma-subunits of NGF. We demonstrate that the beta-NGF precursor produced in mammalian cells via a recombinant vaccinia virus can be cleaved by stoichiometric quantities of the gamma-subunit to produce beta-NGF. Trypsin in catalytic quantities also produces native beta-NGF. Proper cleavage depends critically on the conformation of the precursor. beta-NGF has at least 10-fold more biological activity than its precursor.
Double-blind study with liposteroid in rheumatoid arthritis. (1985)

A multicentre double-blind comparative trial was performed in 138 patients with rheumatoid arthritis (RA) after biweekly intravenous or intramuscular injections of liposteroid (containing 2.5 mg of dexamethasone), which had been developed as a drug for targeting therapy of RA, and Decadron (containing 3.3 mg of dexamethasone) as a reference drug. The results showed a tendency to a significantly higher rate of improvement with lower frequency of side-effects in the liposteroid group than in the Decadron group. This study indicates that liposteroid is more useful for RA and that the separation of the efficacy and side-effects of steroids could be clinically confirmed to some extent.
Localized exciton dynamics in nonpolar (112¯) InxGa1−xN multiple quantum wells grown on GaN templates prepared by lateral epitaxial overgrowth (2005)

Beneficial effects of the localized excitons were confirmed in nonpolar (112¯0) InxGa1−xN multiple quantum wells (QWs) grown on GaN templates prepared by lateral epitaxial overgrowth. Due to the absence of the polarization fields normal to the QW plane, the photoluminescence (PL) peak energy moderately shifted to the higher energy and the radiative lifetime did not change remarkably with the decrease in the well thickness. Similar to the case for polar InGaN QWs, time-resolved PL signals exhibited the nonexponential decay shape, which can be explained by thermalization and subsequent localization of excitons. Although the growth conditions were not fully optimized, values of the PL intensity at 300K divided by that at 8K were 25% and 17% for the peaks at 2.92 and 2.60eV, respectively.
Iron-dependent regulation of transferrin receptor expression in Trypanosoma brucei (1999)

Transferrin is an essential growth factor for African trypanosomes. Here we show that expression of the trypanosomal transferrin receptor, which bears no structural similarity with mammalian transferrin receptors, is regulated by iron availability. Iron depletion of bloodstream forms of Trypanosoma brucei with the iron chelator deferoxamine resulted in a 3-fold up-regulation of the transferrin receptor and a 3-fold increase of the transferrin uptake rate. The abundance of expression site associated gene product 6 (ESAG6) mRNA, which encodes one of the two subunits of the trypanosome transferrin receptor, is regulated 5-fold by a post-transcriptional mechanism. In mammalian cells the stability of transferrin receptor mRNA is controlled by iron regulatory proteins (IRPs) binding to iron-responsive elements (IREs) in the 3′-untranslated region (UTR). Therefore, the role of a T. brucei cytoplasmic aconitase (TbACO) that is highly related to mammalian IRP-1 was investigated. Iron regulation of the transferrin receptor was found to be unaffected in δaco::NEO/δaco::HYG null mutants generated by targeted disruption of the TbACO gene. Thus, the mechanism of post-transcriptional transferrin receptor regulation in trypanosomes appears to be distinct from the IRE/IRP paradigm. The transferrin uptake rate was also increased when trypanosomes were transferred from medium supplemented with foetal bovine serum to medium supplemented with sera from other vertebrates. Due to varying binding affinities of the trypanosomal transferrin receptor for transferrins of different species, serum change can result in iron starvation. Thus, regulation of transferrin receptor expression may be a fast compensatory mechanism upon transmission of the parasite to a new host species.
A Randomly Expandable Method for Data Layout of RAID Storage Systems (2017)

With the increase of huge amounts of data in volume, velocity, and variety, the need for capacity of Redundant Arrays of Inexpensive Disks (RAID) storage systems is dramatically growing. However, the probability of disk failures in RAID storage systems is sharply high with the increase of program/erase cycles, read cycles, and retention time. Furthermore, they are faced with more challenges in fault tolerance, storage efficiency, computational complexity, and expandability. This article presents a novel data layout scheme for RAID storage System using Random Binary Extensive Code (RBEC), which are designed to ensure random expandability, high reliability, and availability of data in RAID storage systems. RBEC is a family of systematic code, in which the generator matrix consists of two submatrices with entries over GF(2), an identity matrix on the top, and another submatrix on the bottom. Compared with the existed approaches, the attractive advantages of our schemes include 1) they are completely implemented based on only simple eXclusive OR (XOR) operations and have systematic code property, 2) they can provide arbitrary fault tolerance, 3) their storage efficiency is quasi-optimal, and 4) data and parity disks of RAID storage systems can be randomly expanded according to practical requirements. Thus, our scheme is particularly suitable for RAID storage systems that need higher reliability, availability, and expandability.
A Modern C++ Point of View of Programming in Image Processing (2022)

C++ is a multi-paradigm language that enables the programmer to set up efficient image processing algorithms easily. This language strength comes from many aspects. C++ is high-level, so this enables developing powerful abstractions and mixing different programming styles to ease the development. At the same time, C++ is low-level and can fully take advantage of the hardware to deliver the best performance. It is also very portable and highly compatible which allows algorithms to be called from high-level, fast-prototyping languages such as Python or Matlab. One fundamental aspects where C++ shines is generic programming. Generic programming makes it possible to develop and reuse bricks of software on objects (images) of different natures (types) without performance loss. Nevertheless, conciliating genericity, efficiency, and simplicity at the same time is not trivial. Modern C++ (post-2011) has brought new features that made it simpler and more powerful. In this paper, we focus on some C++20 aspects of generic programming: ranges, views, and concepts, and see how they extend to images to ease the development of generic image algorithms while lowering the computation time.
From Neighbor-Witness to Judge of Proofs: The Transformation of the English Civil Juror (1988)

Journal Article From Neighbor-Witness to Judge of Proofs: The Transformation of the English Civil Juror Get access John Marshall Mitnick, B.A., J.D. John Marshall Mitnick, B.A., J.D. Associate with Kilpatrick & Cody *Atlanta, Georgia. Emory University, 1984; (Jurisprudence), Oxford University, 1987; University of Virginia, 1988. The author is indebted to Howard S. Mitnick, G.P. Cuttino, J.H. Baker, W. Hamilton Bryson and others who offered valuable comments on earlier drafts of this paper. Search for other works by this author on: Oxford Academic Google Scholar American Journal of Legal History, Volume 32, Issue 3, July 1988, Pages 201–235, https://doi.org/10.2307/845380 Published: 01 July 1988
Enhanced photodegradation of phenolic compounds by adding TiO2 to soil in a rotary reactor (2006)

五氯苯酚(五氯酚) 和在土壤的 p-nitrophenol (PNP ) 的 Photodegradation 在一个设计旋转反应堆被执行，它能向土粒提供不断地一致的照耀，并且在一系列薄土壤层上。作为一种环境友好光催化剂， TiO2 被介绍给土壤提高这些过程。与相比在土壤层上，在 60 mg/kg 的起始的集中的五氯酚的相片降级在旋转反应堆戏剧性地被改进不管 TiO2 是否被增加，随在明显的一阶的率常数的 3.0 次的增加。1 wt% TiO2 的增加到 1.4 次推进了改进。没有 TiO2 的增加， PNP (60 mg/kg 的起始的集中) 在旋转反应堆的相片降级率在土壤层上类似于那。什么时候 1 wt% 另外的 TiO2 被增加， PNP 相片降级显然被提高，并且在旋转反应堆的改进是土壤层上的那的 2 次，它可以在土粒和光催化剂上被归因于在 PNP 之间的接触的更高的频率。土壤 pH 的效果和在旋转反应堆的相片降级上的目标混合物的起始的集中被调查。在不同土壤 pH 的降级率的顺序在在旋转反应堆混合期间相对土粒的聚集。在不同起始的集中的五氯酚和 PNP 的 Photodegradation 显示了 TiO2 的那增加提高相片降级对有五氯酚的更高的集中的污染土壤更合适，当时为在在我们的学习测试的每 PNP 集中的污染土壤是有效的。
Magnetically tunable laser emission from [Hg,Cd]Te (1975)

Tunable spin-flip Raman and recombination laser emission from [Hg,Cd]Te have been observed using a chopped-cw CO2 laser as the pump. Peak powers of over 1 mW and average powers of over 100 μW have been obtained for both the spin-flip Raman and recombination emissions with conversion efficiencies of over 0.3%. A zero-field g factor of ‖82‖±3 has been measured, corresponding to a conduction band-edge effective-mass ratio of 0.0098±0.0004.
High-grade T-cell lymphoma complicating B-cell chronic lymphocytic leukemia: An unusual manifestation of ?Richter's syndrome? (2001)

Approximately 3% of patients with B-cell chronic lymphocytic leukemia (CLL) develop a high-grade large-cell lymphoma consistent with Richter's Syndrome. In most cases, these lymphomas are of B-cell origin and are believed to arise by clonal evolution from the CLL cells. We present a case of a patient with a 10-year history of B-CLL who developed an aggressive large-cell lymphoma, confirmed by immunophenotype to be of T-cell origin. We suggest that in patients with CLL, immunodysregulation can result in the proliferation of T cells, which may mutate and result in the development of a new malignant clone.
Microstructure and Microwave Dielectric Properties of SnO2-Added Ba(Zn1/3Ta2/3)O3 Ceramics (2004)

The Ba(Zn 1/3 Ta 2/3 )O 3 (BZT) ceramic normally has a 1:2-ordered hexagonal structure, but it changes to the 1:1-ordered cubic structure with the addition of SnO 2 . When SnO 2 was added to the BZT ceramics, grain growth occurred and the liquid phase formed. The liquid phase was responsible for the grain growth. The Q × f value of the BZT ceramic significantly increased with the addition of a small amount of SnO 2 . Since the degree of 1:2 ordering and the relative density decreased with the addition of SnO 2 , the enhancement of the Q value cannot be explained by the 1:2 ordering and the relative density. On the other hand, the improvement of the Q value could be related to the increase in the grain size because the average grain size increased with the addition of SnO 2 . However, when a large amount of SnO 2 was added, the Q value was very low. The low Q value was explained by the low relative density and the presence of a large amount of Ba 3 Ta 5 O 15 phase.
Investigation of the Surface Morphology and Photoisomerization of an Azobenzene-Containing Ultrathin Film (1996)

Atomic force microscopy (AFM) and Fourier transform infrared (FTIR) spectroscopy were used to investigate the structure and surface morphology of an azobenzene-containing Langmuir−Blodgett (LB) film. Molecularly-resolved AFM images revealed a slightly distorted monoclinic crystal structure with a unit cell of a = 6.08 ± 0.03 Å, b = 5.67 ± 0.03 Å, and an angle of 55° ± 1° between these two in-plane axes. An average molecular orientation of 39° ± 2° with respect to the film surface normal was determined using FTIR spectra. Using polarized UV excitation of the azobenzene-containing LB film, selective trans-to-cis photoisomerization was obtained and was characterized by the polarized UV−visible spectra. Clear morphological differences between films subjected to unpolarized vs polarized UV illumination were observed with in situ AFM. Domains on the order of 10 nm in diameter or less are thought to be associated with the photoisomerization process.
Triplet-Sensitized Photoreactivity of a Geminal Diazidoalkane (2011)

Photolysis of 1 in chloroform yielded 2 as the major product and a small quantity of 3. Laser flash photolysis demonstrated that upon irradiation, the first excited triplet state of the ketone (T(1K)) of 1 is formed and decayed to form radical 4, which has a λ(max) at 380 nm (τ = 2 μs). Radical 4 expelled a nitrogen molecule to yield imine radical 5 (λ(max) at 300 nm). Density functional theory (DFT) calculations showed that the transition state barrier for the formation of 5 is approximately 4 kcal/mol. In comparison, photolysis of 1 in argon matrices resulted in triplet nitrene 6, which was further characterized with (15)N and D isotope labeling and DFT calculations. Prolonged irradiation of 6 yields triplet imine nitrene 7.
Plasma Neuropeptides in Patients Undergoing Lumbar Discectomy (2007)

These findings indicate the role of plasma CGRP and possibly galanin as a systemic neurochemical signature of pain states in patients with LDH.
Accumulation of c-src mRNA is developmentally regulated in embryonic neural retina. (1986)

Accumulation of c-src mRNA gradually increased during early development of the neural retina in chicken embryos and reached a peak by days 11 to 13 of embryonic life. Thereafter, its amount declined to a low level which persisted also in adult retina. The early increase in c-src mRNA correlated inversely with the decrease in the amount of H3.2 replication histone mRNA and with the decline in the rate of cell growth. The accumulation profile of c-src mRNA corresponded to that of pp60c-src protein, suggesting that the latter is regulated at the level of transcription.
Identification of Differentially Regulated Edwardsiella ictaluri Proteins During Catfish Serum Treatment (2018)

Edwardsiella ictaluri is a facultative, intracellular, gram-negative bacterium that causes enteric septicemia of catfish (ESC). Edwardsiella ictaluri is known to be resistant to defense mechanisms present in catfish serum, which might aid in its use of a host's bloodstream to become septicemic. However, the precise mechanisms of the survival of E. ictaluri in host serum are not known. Analysis of the response of E. ictaluri to the host serum treatment at a proteomic level might aid in the elucidation of its adaptation mechanisms against defense mechanisms present in catfish serum. Thus, the objective of this study was to identify differentially regulated proteins of E. ictaluri upon exposure to naïve catfish serum. Two-dimensional difference gel electrophoresis (2D-DIGE) followed by in-gel trypsin digestion and MALDI-TOF/TOF analysis were used for identification of differentially expressed E. ictaluri proteins. A total of 19 differentially regulated proteins (7 up- and 12 downregulated) were identified. Among those were four putative immunogenic proteins, two chaperones and eight proteins involved in the translational process, two nucleic acid degradation and integration proteins, two intermediary metabolism proteins, and one iron-ion-binding protein. Further research focusing on the functions of these differentially expressed proteins may reveal their roles in host adaptation by E. ictaluri.
Sensitivity of nasopharyngeal swabs and saliva for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (2020)

Abstract We enrolled 53 consecutive in-patients with COVID-19 at six hospitals in Toronto, Canada, and tested one nasopharyngeal swab/saliva sample pair from each patient for SARS-CoV-2. Overall, sensitivity was 89% for nasopharyngeal swabs and 77% for saliva (p=NS); difference in sensitivity was greatest for sample pairs collected later in illness.
Contribution à l'étude du métabolisme et du rôle des nucléotides cycliques dans la thyroïde (1976)

Doctorat en Sciences
3 GHz, 15 W Silicon Bipolar Transistors (2005)

Silicon bipolar transistors delivering 15W output power with 4.8dB gain and 38% collector efficiency have been developed at 3GHz. The transistors have been fabricated by boron ion-implantation for base region and As diffusion from doped poly silicon for emitter region. Chemical dry etching techniques for fine patterning, and internal matching-techniques have been applied.
H (2009)

This chapter contains sections titled: Haidt, Jonathan Happiness Hardiness Harmony Health Psychology Heart-Brain Connection Hedonics Heroes Holistic Healing Honesty Hope Humanistic Psychology Humility Humor References
Efficacy of rehabilitation with different approaches of implant‐supported full‐arch prosthetic designs: A systematic review (2021)

Based on the limited low-quality data, the present analysis points to a low and similar cumulative implant loss within 1 year for patients with tooth loss mainly due to stage IV periodontitis restored with either removable or fixed implant-supported full-arch prosthesis. At 5 years of functioning, there was a tendency for better outcomes using fixed designs.
Photobiomodulation therapy activates YAP and triggers proliferation and dedifferentiation of Müller glia in mammalian retina (2023)

Photobiomodulation therapy has been proposed as a promising therapeutic approach for retinal degenerative diseases. However, its effect on the regenerative capacity in mammalian retina and its intracellular signalling mechanisms remain unknown. Here, we show that photobiomodulation with 670 nm light stimulates Müller glia cell cycle re-entry and dedifferentiation into a progenitor-like state in both the uninjured and injured retina. We also find that 670 nm light treatment inhibits the Hippo pathway, which is activated in Müller glia following NaIO<sub>3</sub>-induced retinal injury. YAP, a major downstream effector of the Hippo signalling pathway was translocated into the nucleus of Müller glia along with YAP dephosphorylation in retina treated with 670 nm light. Deficiency of YAP attenuated Müller glia cell cycle re-entry and dedifferentiation. Our data reveal that the Hippo-YAP signalling pathway is associated with the photostimulatory effect on regenerative response in mammalian retina, and suggest a potential therapeutic strategy for retinal degenerative diseases. [BMB Reports 2023; 56(9): 502-507].
Chromosome pairing affinity and quadrivalent formation in polyploids: do segmental allopolyploids exist? (1996)

When polyploid hybrids with closely related genomes are propagated by selfing or sib-breeding, the meiotic behaviour will turn into essentially autopolyploid behaviour as soon as the affinity between the genomes is sufficient to permit occasional homoeologous pairing. An allopolyploid will only be formed when the initial differentiation is sufficient to completely prevent homoeologous pairing (in some cases enhanced by specific genes), or when segregational dysgenesis prevents transmission of recombined chromosomes. A new polyploid hybrid may be considered a segmental allopolyploid and may show reduced multivalent formation as a result of preferential pairing between the least differentiated genomes. An established polyploid is either an autopolyploid or an allopolyploid. In exceptional cases it is thinkable that a stable segmental allopolyploid arises, in which some sets of chromosomes are well differentiated and behave as in an allopolyploid, whereas other sets are not well differentiated and behave as in an autopolyploid. No clear cases have been found in the literature so far. Key words : chromosome, pairing affinity, quadrivalent frequency, segmental allopolyploidy.