gebhart/patrepeval huggingface dataset:
Pilot Study to Compare the Use of End‐Tidal Carbon Dioxide–Guided and Diastolic Blood Pressure–Guided Chest Compression Delivery in a Swine Model of Neonatal Asphyxial Cardiac Arrest (2018)

Background The American Heart Association recommends use of physiologic feedback when available to optimize chest compression delivery. We compared hemodynamic parameters during cardiopulmonary resuscitation in which either end-tidal carbon dioxide ( ETCO <sub>2</sub>) or diastolic blood pressure ( DBP ) levels were used to guide chest compression delivery after asphyxial cardiac arrest. Methods and Results One- to 2-week-old swine underwent a 17-minute asphyxial-fibrillatory cardiac arrest followed by alternating 2-minute periods of ETCO <sub>2</sub>-guided and DBP -guided chest compressions during 10 minutes of basic life support and 10 minutes of advanced life support. Ten animals underwent resuscitation. We found significant changes to ETCO <sub>2</sub> and DBP levels within 30 s of switching chest compression delivery methods. The overall mean ETCO <sub>2</sub> level was greater during ETCO <sub>2</sub>-guided cardiopulmonary resuscitation (26.4±5.6 versus 22.5±5.2 mm Hg; P=0.003), whereas the overall mean DBP was greater during DBP -guided cardiopulmonary resuscitation (13.9±2.3 versus 9.4±2.6 mm Hg; P=0.003). ETCO <sub>2</sub>-guided chest compressions resulted in a faster compression rate (149±3 versus 120±5 compressions/min; P=0.0001) and a higher intracranial pressure (21.7±2.3 versus 16.0±1.1 mm Hg; P=0.002). DBP -guided chest compressions were associated with a higher myocardial perfusion pressure (6.0±2.8 versus 2.4±3.2; P=0.02) and cerebral perfusion pressure (9.0±3.0 versus 5.5±4.3; P=0.047). Conclusions Using the ETCO <sub>2</sub> or DBP level to optimize chest compression delivery results in physiologic changes that are method-specific and occur within 30 s. Additional studies are needed to develop protocols for the use of these potentially conflicting physiologic targets to improve outcomes of prolonged cardiopulmonary resuscitation.
AC Reactive Sputtering with Inverted Cylindrical Magnetrons (2000)

Inverted cylindrical magnetron sputtering is an excellent way to coat materials at high rates onto complex shapes, such as those used in the biomedical, aerospace, and machine tool industries. Many of these applications require ceramics, which can be deposited most effectively with reactive sputtering. In the past several years, pulsed DC power has become a useful means to avoid arcing when reactively sputtering insulating compounds with planar magnetrons. However, the geometry of inverted cylindrical magnetrons creates an acute “hidden anode” problem that makes pulsed DC reactive sputtering ineffective in these devices. Therefore, we have built a dual-cathode inverted cylindrical magnetron that can be driven with mid-frequency power. Unlike dual-cathode mid-frequency sputtering with two planar magnetrons, this cathode has a common magnetic trap over both electrodes and confines the individual plasmas electrostatically. We have sputtered aluminum nitride and aluminum oxide at deposition rates that are approximately 40% of the aluminum metal rate in each case. The reactivity of aluminum nitride is such that any desired nitrogen partial pressure is accessible using nitrogen flow control and rapid pumping alone. Aluminum oxide, on the other hand, requires feedback control of the oxygen flow to maintain an arbitrary oxygen partial pressure and we have used the target voltage as the control signal. The index and absorbance of films deposited onto glass were calculated from their spectral transmittance and reflectance and agree with reported bulk values. Preliminary data for titanium oxide are presented as well.
Infrared spectroscopic study of polaron formation in electrochemically synthesised poly(3-alkylpyrroles) (2003)

Ex-situ infrared absorption spectroscopy was performed on electrochemically synthesised poly(3-alkylpyrroles) as a function of the alkyl chain length (poly(3-hexylpyrrole) or poly(3-decylpyrrole)) and the counterion (tosylate, perchlorate, tetrafluoroborate, or hexafluorophosphate). More accurate vibrational assignments were made on the basis of the band shift on deuteration of 3-decylpyrrole. In-situ FT-IR spectroscopy was also performed varying the oxidation state of electrochemically polymerised poly(3-alkylpyrroles) from the “undoped” neutral state to the “doped” conductive one. The enhancement and frequency shift of infrared bands as a function of the potential was studied from −0.4 V (vs. Ag/AgCl (sat.)) to 1.0 V for poly(3-decylpyrrole)perchlorate (P3DP(ClO4)) and from −0.5 V to 0.7 V for poly(3-decylpyrrole)tosylate (P3DP(TsO)). The charge passed during the entire oxidative process is associated with the generation of charge carriers. Infrared absorption bands at approx. 1500 cm−1 and 1530 cm−1, ascribed to cooperative skeletal stretching of pyrrole moieties, relate to the formation of polarons and bipolarons, respectively. Both types of charge carriers coexist throughout the potential values where oxidation of the polymer takes place. Bipolarons prevail over polarons at higher potential values (higher than 0.4 V and 0.0 V for P3DP(ClO4) and P3DP(TsO) respectively). The effective shielding of the positive charge by tosylate, due to its effective coordination to the hydrogen of the pyrrole moiety, enhances the formation of the bipolaron over the polaron at lower potentials (0.0 V) with respect to the case when perchlorate is employed (0.4 V). The shielding of the tosylate causes the bipolarons to extend over fewer pyrrole moieties than in the case of perchlorate with a consequent increase of the stiffness of the oxidised polymer. This gives rise to a lower electrical conductivity in the case of P3DP(TsO) (10−3 S cm−1) with respect to P3DP(ClO4) (10−1 S cm−1).
INTRINSICALLY BROKEN CHALCOGEN CHEMICAL ORDER IN STOICHIOMETRIC GLASSES (1981)

The chalcogen site in bulk glasses of GeSe2 and GeS2 has been probed via nuclear quadrupole interactions using 129mTe impurity atoms as parent in 129I Mössbauer emission spectroscopy. Two distinct types of chalcogen sites are observed and are shown to provide direct evidence for intrinsically broken chemical ordering in these network glasses. The compositional dependence of the site parameters in pseudo-binary alloy glasses indicates the presence of characteristic clusters rather than a continuous random network.
Technical Modifications in the Repair of Acute Ischemic Posterior Ventricular Septal Defect Without Ventriculotomy (2015)

The transatrial repair of an acute ischemic posterior ventricular septal defect is a safe technique. The addition of interlocking pledgetted sutures and a patch suture line buttress decreases the incidence of residual and recurrent septal shunt.
White Organic Electroluminescent Devices Fabricated Using Ink-Jet Printing Method (2004)

White organic electroluminescent devices fabricated using the ink-jet printing method have been investigated. The solution of organic materials was composed of a hole transport material, an electron transport material and an emission material dissolved in 1,2-dichloroethane. A maximum luminance of 3,600 cd/m2, maximum external quantum efficiency of 4.15% and Commission International de l'Éclairage chromaticity of (x,y)=(0.29,0.33) have been obtained from the device with poly(9-vinylcarbazole) as host material, 2,5-bis(1-naphthyl)-1,3,4-oxadiazole as electron transport material, a mixture of perylene and 4-dicyanomethylene-6-cp-julolidinostyryl-2-tert-butyl-4H-pyran as emission materials, and cesium as cathode.
Low loss and broadband hollow-core photonic crystal fibers (2011)

We report on recent developments on fabrication and optical guidance of Kagome-lattice hollow-core photonic crystal fiber (HC-PCF). These include the design and fabrication of a hypocycloid-shaped core Kagome HC-PCF that combines a record optical attenuation with a baseline exhibiting ~180 dB/km over a transmission bandwidth larger than 200 THz. These results are corroborated with theoretical simulations which show that both the core-shape and the cladding ring number play role in inhibited coupling, inducing core-mode confinement for the fundamental transmission band. We also show that the inhibited coupling is weaker for the first higher-order transmission band by theoretically and experimentally comparing Kagome HC-PCF with a single anti-resonant ring hollow-core fiber.
Concentration and Fractionation of Small Particles in Liquid by Ultrasound (1995)

The efficacy of the ultrasonic standing plane wave in concentrating small particles was theoretically evaluated and compared with experimental results. Acoustic energy density was estimated by measuring the ultrasonic absorption, and particle distribution was observed by dark-field microscopy. The theory predicts that diffusion is negligible in concentrating polystyrene spheres larger than 5 µ m in diameter when they are subjected to 2 J/m 3 ultrasound. The half-width of the steady-state particle distribution was of the same order of magnitude as the theoretical value for the particles of 1 µ m and 2 µ m diameter. We also applied this concentrating technique to fractionation of polystyrene spheres 10 µ m in diameter, and more than 90% of the particles in the laminar flow were successfully collected.
Analyses of Multiple Film Cracking in Film/Substrate Systems (2001)

Multiple film cracking in a film/substrate system is analyzed in the present study. The system is subjected to residual stresses before loading. A constant displacement rate is applied unidirectionally to stretch the system. An analytical model is developed to derive the stress distribution in the system, and the film‐cracking problem is analyzed using both the strength and the energy criteria. The predicted crack spacing as a function of the applied strain is compared with experimental measurements of multiple cracking of SiO x films with various thicknesses on poly(ethylene terephthalate) substrates. Comparison is also made between the present and other predictions.
Middle cerebral artery blood velocity during rowing (1997)

Dynamic exercise increases the transcranial Doppler determined mean blood velocity in basal cerebral arteries corresponding to the cortical representation of the active limb(s) and independent of the concomitant rise in the mean arterial pressure. In 12 rowers we evaluated the middle cerebral artery blood velocity response to ergometer rowing when regulation of the cerebral perfusion is challenged by stroke synchronous fluctuation in arterial pressure. Rowing increased mean cerebral blood velocity (57 +/- 3 to 67 +/- 5 cm s-1; mean +/- SE) and mean arterial (86 +/- 6 to 97 +/- 6 mmHg) and central venous pressures (0 +/- 2 to 8 +/- 2 mmHg; P < 0.05). The force on the oar triggered an averaging procedure that demonstrated stroke synchronous sinusoidal oscillations in the cerebral velocity with a 12 +/- 2% amplitude upon the average exercise value. During the catch phase of the stroke, the mean velocity increased to a peak of 88 +/- 7 cm s-1 and it was in phase with the highest mean arterial pressure (125 +/- 14 mmHg), while the central venous pressure was highest after the stroke (20 +/- 3 mmHg). The results suggest that during rowing cerebral perfusion is influenced significantly by the rapid fluctuations in the perfusion pressure.
Correlation of blood levels of vascular endothelial growth factor (VEGF) and epidermal growth factor receptor and hemoglobin with response to therapy in advanced non-small cell lung cancer patients (NSCLC) (2005)

7228 Background: VEGF and EGFR are important angiogenic factors involved in cell proliferation and tumor growth. We have investigated the association of serum VEGF and EGFR and hemoglobin levels with clinical outcome in patients with advanced NSCLC. Methods: In 100 patients with stage IIIB and IV NSCLC, treated with gemcitabine/cisplatin, blood was collected before chemotherapy. Serum VEGF and EGFR levels were assessed by commercial ELISA. Anemia was defined as hemoglobin level below 11 g/dl. Results: 91% of the patients were males and the mean age was 61 years [35–82]. 86% had ECOG PS 0–1 and 14% PS 2. 71% had stage IV disease. The histological subtypes were: 38% squamous cell carcinoma, 37% adenocarcinoma, 5% anaplastic large cell, and 20% undifferentiated. Patients received a median of 6 cycles chemotherapy [1–7]. 42% had objective response (4% CR and 38% PR), 25% stable disease (SD) and 30% progressive disease (PD). VEGF and EGFR serum levels were not significantly different with respect to stage, histology or PS. Besides, there were no differences with regard to response rates; In CR and PR patients median EGFR was 63.5 ng/ml [7.5–302] and VEGF 364.4 pg/ml [51–4015] versus a median EGFR level at 62.6 ng/ml [15.3–227.8] and VEGF 570.8 pg/ml [143–1452] in the SD/PD group. Patients with local metastasis had lower median EGFR levels that patients with distant metastasis, 55.5 ng/ml [7.5–85.7] vs 68.7 ng/ml [12.8–302] (p<0.05), respectively. In multivariate analyses, EGFR and VEGF levels were not found to be predictors for anaemia, time to progression, or survival. Conclusions: In advanced NSCLC patients we have not found serum VEGF and EGFR levels to correlate with stage, histology, response, time to progression or survival. VEGF levels were not associated with anaemia after therapy, however, higher EGFR levels were associated with the presence of distant metastasis. No significant financial relationships to disclose.
Understanding substrate-driven growth mechanism of copper silicide nanoforms and their applications (2023)

The growth mechanism of various nanoforms of copper/copper silicide on Si substrates with different orientations is reported here. The triangular, square and rectangular copper/copper silicide nanostructures are deposited on silicon substrates with (111), (100) and (110) orientations respectively, by thermal evaporation of metallic copper at different substrate temperatures. Investigations confirm that the nanostructures consist of a pure copper layer on top of a copper silicide layer. The morphology and growth behaviour studies confirmed for the first time that the formation of well-defined structures and shapes are governed by the Si substrate orientation and the surface reconstruction of the Si planes. The copper silicide nanostructures are used in field emission applications and also serve as a template for the growth of carbon nano-fibre.
Inhibition of P2X7 receptor ameliorates transient global cerebral ischemia/reperfusion injury via modulating inflammatory responses in the rat hippocampus (2012)

Our study indicates that inhibiting P2X7Rs protects against transient global cerebral I/R injury by reducing the I/R-induced inflammatory response, which suggests inhibition of P2X7Rs may be a promising therapeutic strategy for clinical treatment of transient global cerebral I/R injury.
Staphylococcal phosphoenolpyruvate-dependent phosphotransferase system: purification and characterization of a defective lactose-specific factor III protein (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStaphylococcal phosphoenolpyruvate-dependent phosphotransferase system: purification and characterization of a defective lactose-specific factor III proteinH. M. Sobek, K. Stueber, K. Beyreuther, W. Hengstenberg, and Josef DeutscherCite this: Biochemistry 1984, 23, 19, 4460–4464Publication Date (Print):September 11, 1984Publication History Published online1 May 2002Published inissue 11 September 1984https://pubs.acs.org/doi/10.1021/bi00314a034https://doi.org/10.1021/bi00314a034research-articleACS PublicationsRequest reuse permissionsArticle Views12Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Absence of Injury Is Not Absence of Pain: Prevalence of Preseason Musculoskeletal Pain and Associated Factors in Collegiate Soccer and Basketball Student Athletes (2022)

Unlike musculoskeletal (MSK) injuries, MSK pain is rarely studied in athletes. In this study, we examined the prevalence of preseason MSK pain in apparently healthy collegiate soccer and basketball players and its relationship with previous injuries (1-year history), among other factors. Ninety-seven eligible student athletes (mean age: 20.1 (SD: 1.6) years; 43% male; 53% soccer players) completed a baseline questionnaire comprising questions related to demographics, medical and 1-year injury history and any current MSK pain and the corresponding body location. The overall prevalence of preseason MSK pain was 26% (95% CI: 17-36%) and it did not differ by sex or sport. The back (6.2%) and knee (5.2%) regions were reported to be the most frequently affected body parts for preseason MSK pain. Athletes with a previous injury and with perception of incomplete healing had 3.5-fold higher odds (OR: 3.50; 95% CI: 1.28-9.36) of baseline MSK pain compared with those without a previous injury. One in four collegiate soccer and basketball players had preseason MSK pain. Collegiate sports medicine professionals should consider conducting routine preseason evaluations of MSK pain in their athletes and initiate appropriate interventions for the prevention of MSK pain and its potential consequences among athletes.
Survol des principaux types de lentilles cornéennes chez les enfants aphaques âgés de moins de 5 ans (2014)

L’ajustement en lentille cornéenne est souvent le premier choix pour la correction visuelle des enfants aphaques. Il existe plusieurs types de lentilles qui peuvent être ajustées avec succès pour corriger l’amétropie, stimuler adéquatement le développement visuel, mais également préserver la santé oculaire. Plusieurs facteurs sont déterminants pour le choix du type de lentille. Habituellement, la lentille initialement ajustée est en silicone élastofilcon A (Silsoft; Bausch &amp; Lomb, Rochester, ny) avec une migration vers une lentille silicone hydrogel sur mesure avec le temps. Bien que l’ajustement chez les jeunes enfants aphaques présente de nombreux défis, les lentilles cornéennes demeurent souvent l’option de choix de la correction des amétropies après une chirurgie de cataracte congénitale. Un survol des principaux types de lentilles cornéennes disponibles pour les enfants aphaques ainsi que leurs caractéristiques sera présenté.
Heterojunction of Zinc Blende/Wurtzite in Zn1–xCdxS Solid Solution for Efficient Solar Hydrogen Generation: X-ray Absorption/Diffraction Approaches (2015)

In the past decade, inorganic semiconductors have been successfully demonstrated as light absorbers in efficient solar water splitting to generate chemical fuels. Pseudobinary semiconductors Zn1-xCdxS (0≤x≤1) have exhibited a superior photocatalytic reactivity of H2 production from splitting of water by artificial solar irradiation without any metal catalysts. However, most studies had revealed that the extremely high efficiency with an optimal content of Zn1-xCdxS solid solution was determined as a result of elevating the conduction band minimum (CBM) and the width of bandgap. In addition to corresponding band structure and bandgap, the local crystal structure should be taken into account as well to determine its photocatalytic performance. Herein, we demonstrated the correlations between the photocatalytic activity and structural properties that were first studied through synchrotron X-ray diffraction and X-ray absorption spectroscopy. The crystal structure transformed from zinc blende to coexisted phases of major zinc blende and minor wurtzite phases at a critical point. The heterojunction formed by coexistence of zinc blende and wurtzite phases in the Zn1-xCdxS solid solution can significantly improve the separation and migration of photoinduced electron-hole pairs. Besides, X-ray absorption spectra and UV-vis spectra revealed that the bandgap of the Zn0.45Cd0.55S sample extended into the region of visible light because of the incorporation of Cd element in the sample. These results provided a significant progress toward the realization of the photoelectrochemical mechanism in heterojunction between zinc blende and wurtzite phases, which can effectively separate the charge-carriers and further suppress their recombination to enhance the photocatalytic reactivity.
Triazine Herbicides (2012)

This chapter contains sections titled: Introduction History Synthesis Mode of Action Biological Activity Structure–Activity Relationships References
Studies on a single immunoglobulin-binding domain of protein L from Peptostreptococcus magnus: the role of tyrosine-53 in the reaction with human IgG (2001)

Chemical modification experiments with tetranitromethane (TNM) have been used to investigate the role of tyrosine residues in the formation of the complex between PpL (the single Ig-binding domain of protein L, isolated from P. magnus strain 3316) and the kappa light chain (kappa-chain). Reaction of PpL with TNM causes the modification of 1.9 equiv. of tyrosine (Tyr(51) and Tyr(53)) and results in an approx. 140-fold decrease in affinity for human IgG. Similar experiments with mutated PpL proteins suggest that nitration predominantly inactivates the protein by modification of Tyr(53). Reduction of the nitrotyrosine groups to aminotyrosine by incubation with sodium hydrosulphite does not restore high affinity for IgG. Modification of kappa-chain by TNM resulted in the nitration of 3.1+/-0.09 tyrosine residues. When the PpL-kappa-chain complex was incubated with TNM, 4.1+/-0.04 tyrosine residues were nitrated, indicating that one tyrosine residue previously modified by the reagent was protected from TNM when the proteins are in complex with each other. The K(d) for the equilibrium between PpL, human IgG and their complex has been shown by ELISA to be 112+/-20 nM. A similar value (153+/-33 nM) was obtained for the complex formed between IgG and the Tyr(64)-->Trp mutant (Y64W). However, the K(d) values for the equilibria involving the PpL mutants Y53F and Y53F,Y64W were found to be 3.2+/-0.2 and 4.6+/-1 microM respectively. These suggest that the phenol group of Tyr(53) in PpL is important to the stability of the PpL-kappa-chain complex.