gebhart/patrepeval huggingface dataset:
A Parallel IP Address Lookup Scheme for High-Speed Routers (2004)

인터넷에서 IP 패킷을 목적지로 전달하는 라우터는 목적지의 주소에 따라서 다음 홉을 결정하는 IP 주소를 검색하는 과정을 수행한다. 패킷을 전달하는 과정에서 주소 검색은 고속의 라우터의 설계에 중요한 요인이다. 본 논문에서는 이미 하드웨어로 구현된 간접 IP 주소 검색 칩셋의 변경 없이 고속의 라우터의 설계를 위해서 여러 개의 검색 엔진으로 구성된 병렬 주소 검색 기법을 제안한다. 또한, 라우터 시스템 전체 포워딩 테이블에 존재하는 IP 프리픽스 엔트리를 각각의 검색 엔진에 분할하는 규칙을 제시한다. 본 논문에서 제안한 주소 검색 기법의 성능은 IP 프리픽스에 대한 포워딩 정보를 저장하는데 필요한 메모리의 양과 포워딩 테이블을 구성하기 위해 필요한 메모리 접근 횟수로 평가하였다. 본 논문에서 제안한 기법은 한 개의 검색 엔진을 사용하였을 때에 비해서 네 개의 검색 엔진을 사용할 경우, 하드웨어 로직의 도움으로 약 35%의 메모리 양의 감소와 80%의 메모리 접근 횟수의 감소를 보여준다. In order that routers forward a packet to its destination, they perform IP address lookup which determines the next hop according to the packet's destination address. In designing high speed routers, IP address lookup is an important issue. In order to design high speed routers, this paper proposes a parallel IP lookup scheme which consists of several IP lookup engines without any modification of already fabricated indirect IP lookup chipsets. Also, we propose a simple rule for partitioning IP prefix entries In an overall forwarding table among several IP lookup engines. And we evaluate the performance of the proposed scheme in terms of the memory size required for storing lookup information and the number of memory accesses on constructing the forwarding table. With additional hardware logics, the proposed scheme can reduce about 30% of the required memory size and 80% of the memory access counts.
Optical neurocomputing using liquid crystal spatial light modulators (1988)

The significant feature of neurocomputers is their highly interconnected architectures. Fast switching speeds are not essential. Therefore, the devices required to build these computing networks have the design specifications of low-energy dissipation and the need to scale with network size. Nematic and ferroelectric liquid crystals have the characteristics of low switching energy (subpicojoule), large size (commonly used in flat panel displays), and sufficient operating speeds (milliseconds to microseconds).
425 Characteristics of Silicon Nano Wire Piezoresistors (2001)

Si nano wire piezoresistor, whose minimum cross-sectional area is 53nm x 53nm, was fabricated by combination of electron beam (EB) direct writing and RIE. In order to confirm an ability of the Si nano wire piezoresistor as a sensing element of mechanical sensor, the piezoresistive effect was investigated. Longitudinal piezoresistive coefficient π_<l[011]> of the nano wire piezoresistor increased, while transverse piezoresistive coefficient π_<t[01^^-1]>^- decreased with decreasing the cross-sectional area. The maximum value of the longitudinal piezoresistive coefficient π_<l[011]> was 48 x 10^<-5> (1/MPa) at impurity concentration of 5 x 10^<19> (cm^<-3>).
Update on the Effectiveness of High Retention Seats in Preventing Fatal Injury in Rear Impacts (2014)

Vehicles with high retention seats significantly reduced the odds for fatal injury by 46.3% (95% CI, 39.3-52.4, P <.0001) in rear impacts compared to vehicles with earlier seat designs. The new generation of yielding seats has significantly improved occupant safety in rear impacts.
Molecular Basis for Mycophenolic Acid Biosynthesis in Penicillium brevicompactum (2011)

Mycophenolic acid (MPA) is the active ingredient in the increasingly important immunosuppressive pharmaceuticals CellCept (Roche) and Myfortic (Novartis). Despite the long history of MPA, the molecular basis for its biosynthesis has remained enigmatic. Here we report the discovery of a polyketide synthase (PKS), MpaC, which we successfully characterized and identified as responsible for MPA production in Penicillium brevicompactum. mpaC resides in what most likely is a 25-kb gene cluster in the genome of Penicillium brevicompactum. The gene cluster was successfully localized by targeting putative resistance genes, in this case an additional copy of the gene encoding IMP dehydrogenase (IMPDH). We report the cloning, sequencing, and the functional characterization of the MPA biosynthesis gene cluster by deletion of the polyketide synthase gene mpaC of P. brevicompactum and bioinformatic analyses. As expected, the gene deletion completely abolished MPA production as well as production of several other metabolites derived from the MPA biosynthesis pathway of P. brevicompactum. Our work sets the stage for engineering the production of MPA and analogues through metabolic engineering.
A Novel and Efficient Synthesis of Terminal Arylacetylenes via Sonogashira Coupling Reactions Catalysed by MCM-41-supported Bidentate Phosphine Palladium(0) Complex (2007)

A variety of terminal arylacetylenes have been conveniently synthesised in good to high yields via Sonogashira coupling of aryl iodides with (trimethylsilyl)acetylene catalysed by a MCM-41-supported bidentate phosphine palladium(0) complex, followed by desilylation. The polymeric palladium catalyst can be reused many times without any decrease in activity.
Chemometrics and distributed software (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChemometrics and distributed softwareD. L. Massart and P. K. HopkeCite this: J. Chem. Inf. Comput. Sci. 1985, 25, 3, 308–313Publication Date (Print):August 1, 1985Publication History Published online1 May 2002Published inissue 1 August 1985https://doi.org/10.1021/ci00047a029RIGHTS & PERMISSIONSArticle Views63Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (2 MB) Get e-Alerts
The Mosaic Navigator: The Essential Guide to the Internet Interface (1995)

The Nature of the Connection Downloading and Installing Mosaic for Microsoft Windows Installing Mosaic on a Macintosh Mosaic and the World Wide Web Making Mosaic's Tools Work Exploring Mosaic's Menus Customizing Mosaic Robots, Wanderers, and the Future of Mosaic A Travelogue of Interesting Sites Index.
Supplementary Information from Preclinical Pharmacokinetics, Tolerability, and Pharmacodynamics of Metuzumab, a Novel CD147 Human–Mouse Chimeric and Glycoengineered Antibody (2023)

&lt;p&gt;Supplementary Information. including Materials and methods&lt;/p&gt;
On the dimension of subfield subcodes (1990)

A new lower bound for the dimension of a subfield subcode is given. This bound improves the well-known lower bound of P. Delsarte (1975) and coincides in many cases with the true dimension of the code. Alternant codes and geometric Goppa codes are discussed as special cases.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Design &amp; implementation of laboratory information management system based on agile method (2012)

Agile software development is a new methodology of developing high quality software timely when facing significant change; it is convenient for managers to accomplish the collection, disposal, output and other work to the data. There are chart and table functions to the output data and information of laboratories, functions of the output of original and final reports of laboratories, making it affiance to precede the quality control of the data and to help managers arrange analytical plans, staff and other daily work.
Aspirin Decreases Systemic Exposure to Clopidogrel Through Modulation of P-Glycoprotein But Does Not Alter Its Antithrombotic Activity (2014)

Decreased oral clopidogrel absorption caused by induction of intestinal permeability glycoprotein (P-gp) expression after aspirin administration was observed in rats. This study evaluated the effect of aspirin coadministration on the pharmacokinetics/pharmacodynamics of clopidogrel in humans. A single 75-mg dose of clopidogrel was orally administered before and after 2 and 4 weeks of once-daily 100-mg aspirin administration in 18 healthy volunteers who were recruited based on CYP2C19 and PON1 genotypes. Plasma concentrations of clopidogrel and its active metabolite, H4, and relative platelet inhibition (RPI) were determined. The P-gp microRNA miR-27a increased by up to 7.67-fold (P = 0.004) and the clopidogrel area under the concentration-time curve (AUC) decreased by 14% (P > 0.05), but the AUC of H4 remained unchanged and RPI increased by up to 15% (P = 0.002) after aspirin administration. These findings indicate low-dose aspirin coadministration may decrease clopidogrel bioavailability but does not decrease its efficacy.
Metallomics in pulmonary arterial hypertension patients (2023)

Pulmonary arterial hypertension (PAH) prevalence is increasing worldwide, and the prognosis is poor with 5-year survival < 50% in high risk patients. The relationship between metal exposure/essential metal dyshomeostasis and PAH/right ventricular dysfunction is less investigated. The aim of this study is to investigate vegetable consumptions and metal levels between PAH patients and controls. This was a prospective, single center pilot study. Questionnaires were completed by all study subjects (20 PAH patients and 10 healthy controls) on smoking, metal exposure risks, metal supplements, and vegetable consumptions. Blood and urine samples were collected to measure 25 metal levels in blood, plasma, and urine using an X Series II quadrupole inductively coupled plasma mass spectrometry. Statistical analysis was conducted using SAS 9.5 and results with <i>p</i> value < 0.05 were considered significant. Vegetables consumptions (broccoli risk ratio [RR] = 0.4, CI = (0.2, 0.9)], cabbage [RR = 0.2, CI = (0.1, 0.8)], and brussel sprouts [RR = 0.2, CI = (0.1, 0.5)]) are associated with less risks of PAH. In the plasma samples, silver (<i>p</i> < 0.001), and copper (<i>p</i> = 0.002) levels were significantly higher in PAH patients. There was significant positive correlation between cardiac output and cardiac index with plasma levels of silver (<i>r</i> = 0.665, <i>p</i> = 0.001 and <i>r</i> = 0.678 <i>p</i> = 0.001), respectively. There was significant correlation between mixed venous saturation, 6-min walk distance, and last BNP with plasma levels of chromium (<i>r</i> = -0.520, <i>p</i> = 0.022; <i>r</i> = -0.55, <i>p</i> = 0.014; <i>r</i> = 0.463, <i>p</i> = 0.039), respectively. In conclusion, there are significant differences between PAH and control groups in terms of vegetable consumptions and metal concentrations. Silver and chromium levels are correlated with clinical indicators of PAH severities.
Prostaglandin E2 via Steroidogenic Factor-1 Coordinately Regulates Transcription of Steroidogenic Genes Necessary for Estrogen Synthesis in Endometriosis (2009)

ContextProducts of at least five specific steroidogenic genes, including steroidogenic acute regulatory protein (StAR), which facilitates the initial entry of cytosolic cholesterol into the mitochondrion, side-chain-cleavage enzyme (P450scc), 3β-hydroxy-steroid-dehydrogenase-2 (HSD3B2), 17-hydroxylase/17–20-lyase (P450c17) and aromatase which catalyzes the final step, are necessary for the conversion of cholesterol to estrogen. Expression and biologic activity StAR and aromatase were previously demonstrated in endometriosis but not in normal endometrium. PGE2 induces aromatase expression via the transcriptional factor steroidogenic factor-1 (SF1) in endometriosis, which is opposed by chicken-ovalbumin upstream-transcription factor (COUP-TF) and Wilms’ tumor-1 (WT1) in endometrium.
Preparation and Purification of Hop Acids and Their Derivatives (1996)

Pure individual analogs and stereoisomers of the major α-acids, β-acids, cis and trans-iso-α-acids, cis and trans-ρ-iso-α-acids, tetrahydrodesoxy-α-acids, tetrahydro-α-acids, and cis and trans-tetrahydroiso α-acids have been prepared and isolated using fractional recrystallization, complexation, pH partitioning, and various chromatographic techniques (including preparative normal phase and reverse phase). Their structures were determined by elemental analysis, 1H and 13C NMR, chirooptical methods, gas chromatography-mass spectrometry (MS), MS, UV, and high-performance liquid chromatography. The configurations of cis and trans-iso-α-acids were characterized to help establish the mechanism for the formation of ρ-iso-α-acids. The stereochemistry of tetrahydroiso-α-acids, prepared from α-acids and β-acids, has been clarified. The availability of these pure standards simplifies the analytical procedures, allowing the brewer to take full advantage of the various bittering agents.
Cryo-electron microscopy structure of full length TSH receptor in complex with TSH receptor blocking human monoclonal autoantibody K1-70TM (2022)

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
Frequency Reconfigurable Multiband Handset Antenna Based on a Multichannel Transceiver (2017)

The upcoming standards of wireless communications result in additional and more stringent requirements for antennas in mobile phones. In this paper, we present a frequencyreconfigurable antenna that could potentially be suited for future mobile devices. Frequency reconfigurability is achieved through a cluster of mutually coupled antenna elements that is excited with frequency-dependent weights using a multichannel transceiver. We report a mobile handset antenna cluster measuring 15 × 15 × 1.6 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> that covers the frequency bands of 1.7-2.7, 3.3-4.5, and 5.475-6.425 GHz with an antenna efficiency better than 90%. The operation of the antenna cluster is experimentally verified by feeding all the antenna elements with proper weights using tailor-made power splitters that represent a multichannel transceiver with adjustable amplitude and phase in each branch. The results obtained with the feed networks suggest the feasibility of the reconfigurability concept and pave way for codesign of the antenna and the transceiver.
EPA at 40: Bringing Environmental Protection into the 21st Century (2009)

Sustainability science suggests that effective environmental protection requires an integrated systems approach.
A family of bacteria-regulated, cecropin D-like peptides from Manduca sexta. (1988)

Manduca sexta larvae respond to bacterial challenge by synthesizing a set of antibacterial hemolymph proteins. We have purified and sequenced three members of a family of cecropin D-like bactericidal peptides and isolated a cDNA clone complementary to a closely related bactericidin. Results obtained by Northern hybridization and RNase protection analysis showed that the increased synthesis of bactericidins is due to induction of their mRNA levels and that the synthesis of these peptides is not strictly tissue-specific, in contrast to previous beliefs. Although fat body was a richer source, the relative amounts of bactericidin mRNA were significant in seven other tissues examined.
Reachability analysis of nonlinear systems using trajectory piecewise linearized models (2006)

This paper presents a method to compute overapproximations of the reach set for nonlinear dynamic systems using trajectory piecewise linearized (TPWL) models. Based on existing methods for reachability analysis of linear dynamic systems, the method makes it possible to analyze high-order nonlinear dynamic systems. The effectiveness of the method is illustrated by transient stability assessments of a three-machine electric power network and a ten-machine electric power network.
A novel stream merging algorithm for VOD servers (2004)

Hierarchical stream merging is a technique for efficiently delivering popular media on demand using multicast and client buffers. Though there has been much theoretical study around the performance of stream merging, implementation issues were rarely discussed. We argue that the frequent alterations of client behavior hinder the feasibility of traditional stream merging methods. To address this problem, we proposed a new algorithm named CIM (client initiated merge). Despite a minor compromise in server throughput, the new approach greatly reduces system complexity and control overhead. Working on an event-driven mode, it readily accommodates VCR features such as jump and stop. Both simulation and experimental results are given, confirming that the sacrifice in overall server cost is trivial in comparison with the advantages it introduces.
Membrane Protein Insertion at the Endoplasmic Reticulum (2011)

Integral membrane proteins of the cell surface and most intracellular compartments of eukaryotic cells are assembled at the endoplasmic reticulum. Two highly conserved and parallel pathways mediate membrane protein targeting to and insertion into this organelle. The classical cotranslational pathway, utilized by most membrane proteins, involves targeting by the signal recognition particle followed by insertion via the Sec61 translocon. A more specialized posttranslational pathway, employed by many tail-anchored membrane proteins, is composed of entirely different factors centered around a cytosolic ATPase termed TRC40 or Get3. Both of these pathways overcome the same biophysical challenges of ferrying hydrophobic cargo through an aqueous milieu, selectively delivering it to one among several intracellular membranes and asymmetrically integrating its transmembrane domain(s) into the lipid bilayer. Here, we review the conceptual and mechanistic themes underlying these core membrane protein insertion pathways, the complexities that challenge our understanding, and future directions to overcome these obstacles.
ChemInform Abstract: Structure and Low Temperature Physical Properties of Ba8Cu6Ge40. (2009)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Transport through 90° [010] basal-plane-faced tilt and twist grain boundaries in YBa2Cu3O7−δ thin films (1994)

We have fabricated controlled grain boundaries between a- and c-axis films of YBa2Cu3O7−δ (YBCO). By selectively depositing c-axis and in-plane aligned a-axis YBCO on the same substrate, we have grown nominally 90° [010] basal-plane-faced tilt and twist grain boundaries (BFGB’s and TGB’s) on LaSrGaO4 (LSGO) substrates and have studied their transport. We find that the TGB is very robust, exhibiting high critical current density Jc and weak field dependence, and is as well coupled as our [010] antiphase boundaries. The BFGB is not as strong, but couples better than high-angle [001] tilt grain boundaries in c-axis films. Although the BFGB’s do limit Jc, they do not reduce Jc by more than an order of magnitude and the field dependence is very weak. We discuss these grain boundaries in terms of weak links.
Bulimia (1983)

Bulimia Get access William G. Johnson, Ph.D., William G. Johnson, Ph.D. 1University of Mississippi Medical Center *Reprint information may be obtained by writing William G. Johnson, Ph.D., Professor and Chief, Division of Psychology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216. Search for other works by this author on: Oxford Academic Google Scholar Deborah J. Brief, M.A. Deborah J. Brief, M.A. 1University of Mississippi Medical Center Search for other works by this author on: Oxford Academic Google Scholar Behavioral Medicine Update, Volume 4, Issue 3, Winter 1983, Pages 16–21, https://doi.org/10.1093/abm/4.3.16 Published: 01 December 1983
Table ST1 from ROS Induction Targets Persister Cancer Cells with Low Metabolic Activity in NRAS-Mutated Melanoma (2023)

&lt;p&gt;Table ST1: Summary of growth inhibitory IC50 values (including the corresponding 95% confident intervals (C.I.95%) conducted for neocuproine or MEKi (binimetinib) and primary human cell lines. The table includes the confirmed oncogenic mutation as well as the ratio of neocuproine normalized to the MEKi response.&lt;/p&gt;
Automated quantification and comparison of spatio-temporal GAIT parameters during treadmill and overground walking (2008)

A critical part of rehabilitation is providing effective ways to document changes in balance and mobility restrictions/limitations. For overground walking, spatio-temporal gait parameters are widely collected using the GAITRite instrumented carpet. In addition to overground walking, treadmill walking has been shown to be an important tool in rehabilitation. An important advantage of treadmill walking is control over gait speed, which is essential when comparing most gait parameters over time and between participants, as speed can significantly influence the gait patterns. Thus, in this research, software was developed to analyze pressure data and calculate spatio-temporal gait parameters during treadmill walking. A flexible pressure mat was placed under the belt of any treadmill in order to record the foot pressures while the participant was walking. The calculated treadmill parameters were compared to the parameters obtained during overground walking on the GAITRite carpet at a similar speed and to treadmill walking at a fast speed, with and without hand support. Results showed that the spatio-temporal parameters which described the treadmill gait were similar to those describing overground gait. In addition, speed and hand support was shown to cause substantial changes in all parameters.
Assessment of the application for renewal of the authorization of a feed additive consisting of urea for ruminants (Borealis L.A.T. GmbH, SKW Stickstoffwerke Piesteritz GmbH and Yara France) (2023)

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the application for the renewal of the authorisation of urea as nutritional feed additive. The additive is authorised for use in ruminants with functional rumen (3d1). The applicant provided evidence that the additive currently in the market complies with the existing conditions of authorisation and the production process has not been substantially modified. The FEEDAP Panel considers that there is no evidence to revise the conclusions reached in the previous assessment for the target species, consumer and for the environment when used as a source of non-protein nitrogen under current conditions of use, in ruminants with functional rumen. In the absence of new data, the FEEDAP Panel is not in the position to conclude on the user safety. The Panel retains that previously made conclusion on the efficacy remains valid.
Low-loss polarization control in fiber systems for quantum computation (2023)

Optical quantum information processing exploits interference of quantum light. However, when the interferometer is composed of optical fibers, degradation of interference visibility due to the finite polarization extinction ratio becomes a problem. Here we propose a method to optimize interference visibility by controlling the polarizations to a crosspoint of two circular trajectories on the Poincaré sphere. Our method maximizes visibility with low optical loss, which is essential for quantum light, by using fiber stretchers as polarization controllers. We also experimentally demonstrate our method, where the visibility was maintained basically above 99.9% for three hours using fiber stretchers with an optical loss of 0.02 dB (0.5%). Our method makes fiber systems promising for practical fault-tolerant optical quantum computers.