gebhart/patrepeval huggingface dataset:
Toxic Metals in Different Varieties of Seabuckthorn (Hippophae rhamnoides) (1998)

Seabuckthorn ( Hippophae rhamnoides , L) (Oblepiha, Siberian pineapple, Sandorn, Sha-ji), from the Eleagnaceae family, is one of the most important and leading sources of pharmaceutical, nutritional, and cosmetic products in Tibet, Russia, and China. Hippophae oil is an important component of the cream for protection from cosmic radiation, tan-enhancing, cell tissue regeneration, wound healing, and antiaging properties. It is a good source of natural antioxidants, and is used to boost the body immune system, adaptation to extreme conditions, and increased performance body performance. The fruits, seeds, leaves, and cork contain a large amount of chemical elements, essential oils, vitamins A, B, C, E, carotenoids, flavonoids, palmitic and palmitoleic acids, unsaturated fatty acids, α-sitosterol, proteins, minerals, and many other bioactive compounds. As part of the selection and genetic improvement program to develop superior varieties of higher fruit yield, quality and resistance, varietal difference in the uptake or accumulation of heavy (toxic) metals in the berries was investigated. The variation in the content or accumulation of Zn, Cu, Pb, Cd, and Fe in the berries of three varieties of Hippophae (Chuiskaja, Zivko, and Chechek) with differing morphological, and fruit quality was studied. The plants were grown under similar conditions, at Lisavenko Inst. for fruit trees research in Russia. There was a significant difference in the concentration of the metals among the three varieties. Variety `Tchuiiskaja' was found to have significantly higher concentration ( P &lt; 0.05) of Cu, Pb, and Fe. The lowest concentration of the metals was recorded for the variety `Chechek'. The obtained results enable us to suggest, that the Hippophae varieties may significantly vary in the accumulation toxic elements in their berries. This fact should be well considered during selection and improvement program for Hippophae.
Use of Stent Grafts and Coils in Vessel Rupture and Perforation (2007)

Vessel rupture and perforation are important complications of percutaneous treatment of coronary and peripheral arterial disease. These complications can result in abrupt vessel closure, distal organ injury, bleeding into the surrounding tissue, and death. Prompt management of such complications is therefore critically important. This paper reviews the management of vessel rupture and perforation, including the use of different types of covered stents (balloon-expandable and self-expanding), as well as the various types of embolization coils. Particular focus will be placed on percutaneous coronary artery and peripheral arterial interventions.
Support Vectors and Gradient Dynamics of Single-Neuron ReLU Networks (2022)

Understanding implicit bias of gradient descent for generalization capability of ReLU networks has been an important research topic in machine learning research. Unfortunately, even for a single ReLU neuron trained with the square loss, it was recently shown impossible to characterize the implicit regularization in terms of a norm of model parameters (Vardi &amp; Shamir, 2021). In order to close the gap toward understanding intriguing generalization behavior of ReLU networks, here we examine the gradient flow dynamics in the parameter space when training single-neuron ReLU networks. Specifically, we discover an implicit bias in terms of support vectors, which plays a key role in why and how ReLU networks generalize well. Moreover, we analyze gradient flows with respect to the magnitude of the norm of initialization, and show that the norm of the learned weight strictly increases through the gradient flow. Lastly, we prove the global convergence of single ReLU neuron for $d = 2$ case.
Support for Shortest Path Bridging MAC Mode over Ethernet VPN (EVPN) (2016)

This document describes how Ethernet Shortest Path Bridging MAC mode (SPBM) can be combined with Ethernet VPN (EVPN) to interwork with Provider Backbone Bridging Provider Edges (PBB PEs) as described in the PBB-EVPN solution (RFC 7623).This is achieved via operational isolation of each Ethernet network attached to an EVPN core while supporting full interworking between the different variations of Ethernet networks.
Sn-mesoporphyrin Suppression of Hyperbilirubinemia in EHBR/Eis Rats, an Animal Model of Dubin-Johnson Syndrome (1998)

Sn-mesoporphyrin (SnMP), a potent inhibitor of heme oxygenase (HO), controlled hyperbilirubinemia in rats of the mutant strain EHBR/Eis. This mutant strain displays pronounced conjugated hyperbilirubinuria and dark pigmentation of hepatocytes, characteristics of the Dubin-Johnson syndrome. SnMP administered at a dose of 10 mumol/kg body weight produced an immediate decrease in plasma bilirubin concentrations which could be maintained by weekly injections of this synthetic heme analogue. Marked inhibition of HO activity was demonstrated in liver, kidney and spleen but not in brain. These results demonstrate that SnMP can lower plasma bilirubin concentrations for extended periods in a new mutant rat model of Dubin-Johnson syndrome.
Magnetic circuit model for the mutually coupled switched-reluctance machine (2000)

The mutually coupled switched-reluctance motor (SRM) appears to have several performance advantages over other motor technologies. The existence of strong coupling between phases, however, makes the analysis of this machine quite complicated. Preliminary design of this machine can be greatly accelerated by the ability to evaluate potential motor geometries quickly. This paper introduces a general magnetic circuit model of the mutually coupled SRM that adapts to any geometry, unlike existing geometry-dependent approaches (such as finite elements), which are numerically intensive and require excessive computation time. The model uniquely implements the magneto-motive force (mmf) sources necessary to accommodate complex flux paths through the machine and includes the effects of magnetic saturation. The results are compared to those of a finite element solver to demonstrate the performance of this method as a first-step to evaluating candidate designs.
Biochemical Characterization and Identification of the Catalytic Residues of a Family 43 β-d-Xylosidase from Geobacillus stearothermophilus T-6 (2004)

Beta-D-xylosidases are hemilcellulases that hydrolyze short xylooligosaccharides into xylose units. Here, we describe the characterization and kinetic analysis of a family 43 beta-xylosidase from Geobacillus stearothermophilus T-6 (XynB3). Enzymes in this family use an inverting single-displacement mechanism with two conserved carboxylic acids, a general acid, and a general base. XynB3 was most active at 65 degrees C and pH 6.5, with clear preference to xylose-based substrates. Products analysis indicated that XynB3 is an exoglycosidase that cleaves single xylose units from the nonreducing end of xylooligomers. On the basis of sequence homology, amino acids Asp15 and Glu187 were suggested to act as the general-base and general-acid catalytic residues, respectively. Kinetic analysis with substrates bearing different leaving groups showed that, for the wild-type enzyme, the k(cat) and k(cat)/K(m) values were only marginally affected by the leaving-group reactivity, whereas for the E187G mutant, both values exhibited significantly greater dependency on the pK(a) of the leaving group. The pH-dependence activity profile of the putative general-acid mutant (E187G) revealed that the protonated catalytic residue was removed. Addition of the exogenous nucleophile azide did not affect the activities of the wild type or the E187G mutant but rescued the activity of the D15G mutant. On the basis of thin-layer chromatography and (1)H NMR analyses, xylose and not xylose azide was the only product of the accelerated reaction, suggesting that the azide ion does not attack the anomeric carbon directly but presumably activates a water molecule. Together, these results confirm the suggested catalytic role of Glu187 and Asp15 in XynB3 and provide the first unequivocal evidence regarding the exact roles of the catalytic residues in an inverting GH43 glycosidase.
Using Ontology Design Patterns To Define SHACL Shapes (2018)

SHACL shapes used for validation are not related to the axioms used in ontologies used to define the instances. One of the issues with using such axioms is their dependence on concepts which may not be used within the data graph, as well as the presence of other concepts and relationships which the axioms do not cover. By contrast, an Ontology Design Pattern (ODP) contains axioms that are closer to how its in-stances are defined. In this position paper, we discuss the reuse of ODP axioms from modelling contexts to defining SHACL shapes, using the use-case of MicroblogEntry ODP. The aim of this approach is to foster automated generation of SHACL shapes based on contexts, represented by an ODP, defined within data graphs.
Application of slot line to miniature ferrite devices (1969)

Slot transmission line was introduced by S. B. Cohn in 1968 as an alternative transmission line for microminiature components. Slot line is potentially advantageous when compared to other planar transmission lines for applications requiring regions of circularly polarized magnetic field and/or shunt mounted elements. The line consists of two conductors separated by a gap on one side of a dielectric substrate. The dominant mode is a TE mode as shown in Figure 1. This mode resembles the dominant mode of rectangular waveguide and provides natural regions of circularly polarized magnetic field. Slot line applications will include ferrite phasers, circulators and isolators, diode switches and phasers, and filters. Combined microstrip and slot line circuitry seem to offer new possibilities for systems with the advantage of coupling easily through the substrate from one medium to the other.
P1SM.6 - Thick-film Heavy-metal Sensor of Chalcogenide Glass (2018)

This paper reports on the development and verification of a potentiometric sensor based on chalcogenide glass of novel composition to determine copper ions in aqueous solutions. The sensor is assembled by way of thick-film technology on a ceramic substrate.
<title>Correction of cyclic error in optical waveguide distance meter</title> (1999)

Sinusoidal modulation method is utilized in optical distance meters. In this method, the phase delay of the returned beam is measured with high resolution. One of the dominant error factors in the phase measurement is cyclic error. We have already reported on a cyclic error compensation of an optical waveguide distance meter using a preliminary phase measurement with mechanical displacement. In this paper, a new technique of the cyclic error compensation is described, which is based on the modulation frequency scanning of the waveguide distance meter around 14 GHz. We have compared two types of cyclic error curves; one was obtained from the data during the displacement of the target and the other was obtained from the data during the scanning of the modulation frequency. The curve fitting technique was used to determine the amplitude and the phase of the cyclic error component for the two curves. We have obtained almost the same values for both parameters of the amplitude and the phase for the two cyclic error curves. Therefore, the cyclic error curve obtained from the data of frequency scanning can be utilized for the cyclic error compensation instead of the displacement of the target.
Increasing tissue requirements in lymphoma trials may exclude patients with high-risk disease or worse prognosis (2022)

An enhanced understanding of the molecular heterogeneity of diffuse large B-cell lymphoma (DLBCL) has opened the door to clinical trials evaluating novel agents with subtype-specific activity. It is an emerging question whether core needle biopsies (CNB) can adequately meet the increasing tissue requirements of these clinical trials. This can potentially lead to selective enrollment of patients who can undergo excisional biopsy (EB). It is also important to know whether patients who can undergo extensive diagnostic work up differ in their disease characteristics and outcomes from those who cannot. In this observational study, we describe the characteristics, outcomes, and adequacy of diagnostic tissue in patients with newly diagnosed DLBCL and primary mediastinal large B-cell lymphoma who underwent EB vs CNB. Of the 1061 patients, 532 (49.8%) underwent EB and 529 (50.1%) underwent CNB. A significantly higher proportion of patients with CNB had advanced stage disease, an international prognostic index of ≥3, and inadequate tissue for molecular analyses. Patients with CNB had significantly worse 5-year event-free survival (67.6% vs 56.9%; hazard ratio [HR], 0.76; confidence interval [CI]95, 0.6-0.9, P < .001) and 5-year overall survival (76.4% vs 69.2%; HR, 0.8; CI95, 0.6-0.9, P < .001). Thus, patients who underwent CNB have poor-risk features and inferior outcomes on frontline chemoimmunotherapy, are more likely to have inadequate tissue for molecular analyses, and might not meet the tissue requirements of biomarker-driven clinical trials. Thus, the increasing tissue requirements of biomarker-driven clinical trials may result in the exclusion of patients with high-risk DLBCL who need novel agents.
Dysautonomia among patients with fibromyalgia: a noninvasive assessment. (2000)

Patients with FM have abnormal responses to 2 tests of autonomic nervous system function. Further research is needed to determine if dysautonomia plays a role in the pathogenesis of FM or is a result of FM.
Improving Usability of Interactive Graphics Specification and\n Implementation with Picking Views and Inverse Transformations (2011)

Specifying and programming graphical interactions are difficult tasks,\nnotably because designers have difficulties to express the dynamics of the\ninteraction. This paper shows how the MDPC architecture improves the usability\nof the specification and the implementation of graphical interaction. The\narchitecture is based on the use of picking views and inverse transforms from\nthe graphics to the data. With three examples of graphical interaction, we show\nhow to express them with the architecture, how to implement them, and how this\nimproves programming usability. Moreover, we show that it enables implementing\ngraphical interaction without a scene graph. This kind of code prevents from\nerrors due to cache consistency management.\n
High Index Of Refraction Films For Dielectric Mirrors Prepared By Metal-Organic Chemical Vapor Deposition (1989)

A wide variety of metal oxides with high index of refraction can be prepared by Metal-Organic Chemical Vapor Deposition. We present some recent optical and laser damage results on oxide films prepared by MOCVD which could be used in a multilayer structure for highly reflecting (HR) dielectric mirror applications. The method of preparation affects both optical properties and laser damage threshold.
Near-Field Channel Estimation for Extremely Large-Scale Reconfigurable Intelligent Surface (XL-RIS)-Aided Wideband mmWave Systems (2023)

Near-field communications present new opportunities over near-field channels, however, the spherical wavefront propagation makes near-field signal processing challenging. In this context, this paper proposes efficient near-field channel estimation methods for wideband MIMO mmWave systems with the aid of extremely large-scale reconfigurable intelligent surfaces (XL-RIS). For the wideband signals reflected by the analog RIS, we characterize their near-field beam squint effect in both angle and distance domains. Based on the mathematical analysis of the near-field beam patterns over all frequencies, a wideband spherical-domain dictionary is constructed by minimizing the coherence of two arbitrary beams. In light of this, we formulate a two-dimensional compressive sensing problem to recover the channel parameter based on the spherical-domain sparsity of mmWave channels. To this end, we present a correlation coefficient-based atom matching method within our proposed multi-frequency parallelizable subspace recovery framework for efficient solutions. Additionally, we propose a two-dimensional oracle estimator as a benchmark and derive its lower bound across all subcarriers. Our findings emphasize the significance of system hyperparameters and the sensing matrix of each subcarrier in determining the accuracy of the estimation. Finally, numerical results show that our proposed method achieves considerable performance compared with the lower bound and has a time complexity linear to the number of RIS elements.
Rearrangement of arylhydrazones of aromatic and arylaliphatic carbonyl compounds to biphenyl derivatives. 3 (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRearrangement of arylhydrazones of aromatic and arylaliphatic carbonyl compounds to biphenyl derivatives. 3R. Fusco and F. SannicoloCite this: J. Org. Chem. 1981, 46, 1, 83–89Publication Date (Print):January 1, 1981Publication History Published online1 May 2002Published inissue 1 January 1981https://pubs.acs.org/doi/10.1021/jo00314a018https://doi.org/10.1021/jo00314a018research-articleACS PublicationsRequest reuse permissionsArticle Views633Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Initial operating experience of the 12-MW La Ola photovoltaic system. (2011)

The 1.2-MW La Ola photovoltaic (PV) power plant in Lanai, Hawaii, has been in operation since December 2009. The host system is a small island microgrid with peak load of 5 MW. Simulations conducted as part of the interconnection study concluded that unmitigated PV output ramps had the potential to negatively affect system frequency. Based on that study, the PV system was initially allowed to operate with output power limited to 50% of nameplate to reduce the potential for frequency instability due to PV variability. Based on the analysis of historical voltage, frequency, and power output data at 50% output level, the PV system has not significantly affected grid performance. However, it should be noted that the impact of PV variability on active and reactive power output of the nearby diesel generators was not evaluated. In summer 2011, an energy storage system was installed to counteract high ramp rates and allow the PV system to operate at rated output. The energy storage system was not fully operational at the time this report was written; therefore, analysis results do not address system performance with the battery system in place.
A 26-hour system of highly sensitive whole genome sequencing for emergency management of genetic diseases (2015)

While the cost of whole genome sequencing (WGS) is approaching the realm of routine medical tests, it remains too tardy to help guide the management of many acute medical conditions. Rapid WGS is imperative in light of growing evidence of its utility in acute care, such as in diagnosis of genetic diseases in very ill infants, and genotype-guided choice of chemotherapy at cancer relapse. In such situations, delayed, empiric, or phenotype-based clinical decisions may meet with substantial morbidity or mortality. We previously described a rapid WGS method, STATseq, with a sensitivity of >96 % for nucleotide variants that allowed a provisional diagnosis of a genetic disease in 50 h. Here improvements in sequencing run time, read alignment, and variant calling are described that enable 26-h time to provisional molecular diagnosis with >99.5 % sensitivity and specificity of genotypes. STATseq appears to be an appropriate strategy for acutely ill patients with potentially actionable genetic diseases.
765: Modified Expression of Heat Shock Protein 27 in Renal Cell Carcinoma (2004)

You have accessJournal of UrologyDiscussed Poster, Monday, May 10, 2004, 8:00 am - 12:00 pm1 Apr 2004765: Modified Expression of Heat Shock Protein 27 in Renal Cell Carcinoma Cecilia Sarto, Paolo Favini, Cristina Valsecchi, Stefano Casellato, Fulvio Magni, Gennaro Musi, Luca F. Carmignani, Stefano Ferrero, Francesco Rocco, and Paolo Mocarelli Cecilia SartoCecilia Sarto More articles by this author , Paolo FaviniPaolo Favini More articles by this author , Cristina ValsecchiCristina Valsecchi More articles by this author , Stefano CasellatoStefano Casellato More articles by this author , Fulvio MagniFulvio Magni More articles by this author , Gennaro MusiGennaro Musi More articles by this author , Luca F. CarmignaniLuca F. Carmignani More articles by this author , Stefano FerreroStefano Ferrero More articles by this author , Francesco RoccoFrancesco Rocco More articles by this author , and Paolo MocarelliPaolo Mocarelli More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)38014-5AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "765: Modified Expression of Heat Shock Protein 27 in Renal Cell Carcinoma." The Journal of Urology, 171(4S), p. 203 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 171Issue 4SApril 2004Page: 203 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Cecilia Sarto More articles by this author Paolo Favini More articles by this author Cristina Valsecchi More articles by this author Stefano Casellato More articles by this author Fulvio Magni More articles by this author Gennaro Musi More articles by this author Luca F. Carmignani More articles by this author Stefano Ferrero More articles by this author Francesco Rocco More articles by this author Paolo Mocarelli More articles by this author Expand All Advertisement PDF DownloadLoading ...
Alternative Cancer Cures: "Unproven" or "Disproven"? (2004)

Oncology has always coexisted with therapies offered outside of conventional cancer treatment centers and based on theories not found in biomedicine. These alternative cancer cures have often been described as "unproven," suggesting that appropriate clinical trials have not been conducted and that the therapeutic value of the treatment is unknown. Contrary to much popular and scientific writing, many alternative cancer treatments have been investigated in good quality clinical trials, and they have been shown to be ineffective. In this article, clinical trial data on a number of alternative cancer cures including Livingston-Wheeler, Di Bella Multitherapy, antineoplastons, vitamin C, hydrazine sulfate, Laetrile, and psychotherapy are reviewed. The label "unproven" is inappropriate for such therapies; it is time to assert that many alternative cancer therapies have been "disproven."