gebhart/patrepeval huggingface dataset:
A New Multiple Information Fusion Approach for Astronomical Navigation using Markov Random Field algorithm (2019)

Autonomous navigation is one of the key technologies to ensure the implementation of deep space exploration mission. Astronomical angle measurement information and stellar spectral velocity measurement information are usually used to estimate the real-time navigation state. According to the characteristics and requirements of deep space navigation, this paper proposes a novel method for information fusing using Markov Random Field approach, which integrates the navigation information including angle measurement, velocity measurement and combination of angle and velocity measurement, to realize continuous autonomous, real-time and high-precision navigation of deep space exploration. Considering the background of Mars exploration engineering mission, the observability and precision of the navigation method are analysed. The simulation results show that the method based on Markov Random Field can greatly improve the observability of the navigation system, effectively suppress the influence of measurement error, further improve the accuracy of navigation estimation, enhance the reliability of the navigation system, and provide a new technical approach to realize the high precision autonomous navigation of deep space exploration.
Analysis of fuel options for the breakeven core configuration of the Advanced Recycling Reactor (2013)

A trade-off study is performed to determine the impacts of various fuel forms on the core design and core physics characteristics of the sodium-cooled Toshiba- Westinghouse Advanced Recycling Reactor (ARR). The fuel forms include oxide, nitride, and metallic forms of U and Th. The ARR core configuration is redesigned with driver and blanket regions in order to achieve breakeven fissile breeding performance with the various fuel types. State-of-the-art core physics tools are used for the analyses. In addition, a quasi-static reactivity balance approach is used for a preliminary comparison of the inherent safety performances of the various fuel options. Thorium-fueled cores exhibit lower breeding ratios and require larger blankets compared to the U-fueled cores, which is detrimental to core compactness and increases reprocessing and manufacturing requirements. The Th cores also exhibit higher reactivity swings through each cycle, which penalizes reactivity control and increases the number of control rods required. On the other hand, using Th leads to drastic reductions in void and coolant expansion coefficients of reactivity, with the potential for enhancing inherent core safety. Among the U-fueled ARR cores, metallic and nitride fuels result in higher breeding ratios due to their higher heavy metal densities. On the other hand,more » oxide fuels provide a softer spectrum, which increases the Doppler effect and reduces the positive sodium void worth. A lower fuel temperature is obtained with the metallic and nitride fuels due to their higher thermal conductivities and compatibility with sodium bonds. This is especially beneficial from an inherent safety point of view since it facilitates the reactor cool-down during loss of power removal transients. The advantages in terms of inherent safety of nitride and metallic fuels are maintained when using Th fuel. However, there is a lower relative increase in heavy metal density and in breeding ratio going from oxide to metallic or nitride Th fuels relative to the U counterpart fuels. (authors)« less
An Isolated Venous Sac as a Novel Site for Cell Therapy in Diabetes Mellitus (2012)

We demonstrated that pancreatic islets successfully engrafted and functioned in the isolated venous sac with ability to restore euglycemia in diabetic rats. Therefore, the isolated venous sac offers a new site for transplantation of pancreatic islets. This would be clinically beneficial as an alternative to intrahepatic islet transplantation.
A multiple‐window display (1990)

Abstract A hardware‐controlled multiwindow display is one multiwindow display scheme which makes high‐speed display possible. However, the locations of the windows for an overlapping display are restricted due to limits on the access speed of the window buffer which is storing the window image. In order to deal with this problem, this paper considers a system with a buffer for speed adjustment. A display device was constructed based on the proposed concept, and its performance was evaluated. As a result, for the cases of one and nine windows, 21 times and 147 times faster manipulation rates, respectively, were realized in manipulations such as window shifting, as compared with a software‐controlled window display. In order to examine the effect of window manipulation on drawing performance, the drawing time was measured for cases with window manipulation and without it. As a result, it was shown that there is no significant difference in the processing time, and it was verified that the drawing performance is not degraded by window manipulation.
Time and the Process of Security Price Adjustment (1992)

This paper delineates the link between the existence of information, the timing of trades, and the stochastic process of prices. We show that time affects prices, with the time between trades affecting spreads. Because the absence of trades is correlated with volume, our model predicts a testable relation between spreads and normal and unexpected volume, and demonstrates how volume affects the speed of price adjustment. Our model also demonstrates how the transaction price series will be a biased representation of the true price process, with the variance being both overstated and heteroskedastic.
Research of computer network security evaluation based on RBF neural network (2016)

Nowadays, computer network is widely used in many areas of daily life. Since the affectation of vulnerabilities and viruses, there will be a variety of security issues in the application process of computer network. In order to provide effective protection for computer network security, computer network security evaluation system should be established. This article will use RBF neural network to evaluate the security of the computer network, which will improve the level of computer network security.
Intralesional injection of platelet-rich plasma followed by controlled exercise for treatment of midbody suspensory ligament desmitis in Standardbred racehorses (2008)

Results suggested that horses with moderate to severe MSD treated by means of intralesional injection of a single dose of PRP followed by a program of gradually increased exercise had an excellent prognosis for returning to racing.
Mineralocorticoid Receptors: Evolutionary and Pathophysiological Considerations (2011)

Mineralocorticoid receptors (MR), glucocorticoid receptors (GR), progesterone receptors (PR), and androgen receptors (AR) comprise a closely related subfamily within the human 49-member nuclear receptor family. These receptors and their cognate ligands play major roles in homeostasis, reproduction, growth, and development, despite which their evolution and diversification remains incompletely understood. Several conflicting models have been advanced for the evolution of this subfamily. We have thus undertaken Bayesian and maximum likelihood phylogenetic analyses of this subfamily. The Bayesian consensus and maximum likelihood trees support a basal position for MR, with the PR and AR forming a sister clade. We next performed analyses using topological constraints to directly contrast the likelihood of seven phylogenetic models. In these analyses, three models have similar support: one proposes two sister clades (MR and GR, PR and AR); the other two propose a different subfamily member (MR or GR) to be the first to have diverged. Ancestral state reconstructions at sites critical for physiological function show that the S810L mutation in the MR, which results in the MR being similar to estrogen receptors and the more distantly related retinoic acid receptor-α is likely to reflect the ancestral receptor sequence before the divergence of this subfamily and provides further support for MR having been the first of the subfamily to diverge. Finally, we drew on pathophysiological comparisons to help to distinguish the different models. On the basis of our phylogenetic analyses and pathophysiological considerations, we propose that the MR was the first to diverge from the ancestral gene lineage from which this subfamily derived.
Some Promising Early Results from a Rudimentary Latent-Trait Theory of Performance Rating. (1981)

A theory is discussed in which observed performance ratings are derived from the distance between a rater reference point and subject performance point located on a postulated equal interval scale and a postulated s-shaped rater characteristic curve, opeationalized as the normal ogive. Least-squares estimates of rater (nR=47, 31, and 29) and subject (nS=29, 30, and 35 points were determined separately on each of three junior medical student cohorts' data. The proposed model fit each of the data sets better than. taco alternative models (r is greater than 0.70; p is less than . 0.01). Test-retest reliabilities for rater parameters were r is less than 0.29 (joint p is less than 0.04). Cross-validating results also supported the theory. (Author/RL) *********************************************************************** * ReprodUctions supplied by EDRS are the pest that. can be made * from the original document. ********************************************************************* CP Some Promising Early Results from a Rudimentary Latent-Trait Theory of Performance Rating Gerald J. Cason and Carolyn L. Cason University of Arkansas foc Medical Sciences C=t A theory in which observed performance ratings are derived LA.1 from the distance between a rater reference point and subject performance point located on a postulated equal interval scale and a postulated s-shaped rater characteristic curve, operationalized as the normal ogive, is presented. Least squares estimates of rater (nR=470 31, and 29) and subject (nS=290--300and 35) -points were determined separately on each of three junior medical student cohorts' data. The proposed model fit each of the data sets better than two alternative models (r)0.10 p<0.01). lestretest reliabilities for rater parameters were r<0.29 (joint p<0.04). Cross-validating results also supported the theory.. U S DEPARTMENT OF HEALTH. EDUCATION B. WELFARE NATIONAL INSTITUTE OF EDUCATION THIS DOCUMENT HAS BEEN REPRO. DUCED EXACTLY AS RECEIVED FROM THE PERSON OR ORGANIZATION OR1GiNAIME; IT POINTS OF VIEW OR OPINIONS STATED DO NOT NECESSARILY REPRE SENT OFFICIAL NAT iONAL INSTITUTE OF EDUCATION POSITION OR POLICY PERMISSION TO REPRODUCE THIS MATERIAL HAS BEEN GRANTED BY CzLCg TO THE EDUCATIONAL RESOURCES INFORMATION CENTER (ERIC). Paper presented at the Annual Meeting of the American Educational Research Associations Los Angeles0J981.
Immunotherapy of established murine B cell lymphoma. Combination of idiotype immunization and cyclophosphamide. (1988)

A murine B cell lymphoma (38C13) was used to study the efficacy of idiotype immunotherapy against established tumors. Immunization of mice with 38C13 tumor-derived Ig, administered after a lethal tumor inoculation, significantly prolonged survival of animals compared to control groups. The efficacy of active immunotherapy was dramatically enhanced when combined with chemotherapy. Cyclophosphamide (100 mg/kg), administered in combination with idiotype immunization to mice bearing 10-day-old, 1 to 2 cm diameter s.c. tumors, resulted in a significant prolongation of survival as compared with either cyclophosphamide or immunization alone and yielded approximately 50% cures. Additional studies combining active immunotherapy with surgical excision of the primary s.c. tumor nodule were less effective than combination chemoimmunotherapy, indicating that reduction of tumor burden was necessary, but not sufficient for effective treatment of established 38C13 lymphoma.
Reactive sites of an anticarcinogenic Bowman-Birk proteinase inhibitor are similar to other trypsin inhibitors. (1992)

The three-dimensional structure of the Bowman-Birk type proteinase inhibitor (PI-II) has been determined by x-ray crystallography and refined at 2.5-A resolution. This protein is a specific inhibitor of trypsin. Two reactive site loops, one at each end of the PI-II molecule, are structurally similar to each other and to reactive-site loops of pancreatic secretory trypsin inhibitor (Bolognesi, M., Gatti, G., Menegatti, E., Guarneri, M., Marquart, M., Papamokos, E., and Huber, R. (1982) J. Mol. Biol. 162, 839-869) and bovine pancreatic trypsin inhibitor (Deisenhofer, J., and Steigemann, W. (1975) Acta Crystallogr. B31, 238-250). PI-II is the first reported Bowman-Birk type inhibitor structure to be refined at high resolution, providing further insight into inhibitor mechanisms.
In Situ Multitechnical Investigation into Capacity Fading of High-Voltage LiNi0.5Co0.2Mn0.3O2 (2016)

LiNi<sub>0.5</sub>Co<sub>0.2</sub>Mn<sub>0.3</sub>O<sub>2</sub> positive electrode materials of lithium ion battery can release a discharge capacity larger than 200 mAh/g at high potential (>4.30 V). However, its inevitable capacity fading, which is greatly related to the structural evolution, reduces the cycling performance. The origin of this capacity fading is investigated by coupled in situ XRD-PITT-EIS. A new phase of NiMn<sub>2</sub>O<sub>4</sub> is discovered on the surface of the LiNi<sub>0.5</sub>Co<sub>0.2</sub>Mn<sub>0.3</sub>O<sub>2</sub> upon charging to high voltage, which blocks Li<sup>+</sup> diffusion pathways. Theoretical calculations predict the formation of cubic NiMn<sub>2</sub>O<sub>4</sub>. Moreover, corrosion, cracks, and microstress appear to increase the difficulty of Li<sup>+</sup> transportation, which are attributed to the protection degradation of the interfacial film on the positive electrode material at high voltage. After 50 electrochemical cycles, the increase in degree of crystal defects by low-angle grain boundary, evidenced through HR-TEM, leads to poor Li<sup>+</sup> kinetics, which in turn causes capacity loss. The in situ XRD-PITT-EIS technique can bring multiperspective insights into fading mechanism of the high-voltage positive electrode materials and provide a solution to control or suppress the problem on the basis of structural, kinetic, and electrochemical interfacial understandings.
A model of file server performance for a heterogeneous distributed system (1986)

In this paper, we study the performance characteristics of a client-server style distributed system by a queueing network model. The system being modeled was based on an experimental distributed system currently being prototyped. As a specific detailed case study, we have evaluated the performance of a file server. A file server is a key component to achieve the data sharing necessary in a distributed system. The file server is probably the most heavily used resource of the distributed system and as a result, its performance is critical to the success of the system. The primary goal of the study was to identify and quantify the effects of the bottlenecks in the server and assess design alternatives to enhance performance. In particular, the improvements due to file caching, outboarding transport functions and the effect of multiple network interfaces were studied. We model in detail the various stages of processing of a request to a file server. Parameterization of the model was achieved by initial measurements made on the prototype system. An important characteristic modeled was the buffer overflow from the network interfaces. This required the approximate solution of a non-product-form queueing network.
Data from Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML (2023)

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; To evaluate the safety, efficacy, and immunobiological correlates of allogeneic NK-cell–based therapy in primary chemotherapy-refractory or relapsed high-risk myelodysplastic syndrome (MDS), secondary AML (MDS/AML), and &lt;i&gt;de novo&lt;/i&gt; AML patients.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; Sixteen patients received fludarabine/cyclophosphamide conditioning combined with total lymphoid irradiation followed by adoptive immunotherapy with IL2–activated haploidentical NK cells.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt; NK-cell infusions were well-tolerated, with only transient adverse events observed in the 16 patients. Six patients achieved objective responses with complete remission (CR), marrow CR, or partial remission (PR). Five patients proceeded to allogeneic hematopoietic stem cell transplantation (HSCT). Three patients are still free from disease &gt;3 years after treatment. All evaluable patients with objective responses (5/5 evaluable) had detectable donor NK cells at days 7/14 following infusion and displayed reduction of tumor cell clones, some of which carried poor prognosis mutations. Residual lin&lt;sup&gt;−&lt;/sup&gt;CD34&lt;sup&gt;+&lt;/sup&gt;CD123&lt;sup&gt;+&lt;/sup&gt;CD45RA&lt;sup&gt;+&lt;/sup&gt; blast cells in responders had increased total HLA class I and HLA-E expression. Responding patients displayed less pronounced activation of CD8&lt;sup&gt;+&lt;/sup&gt; T cells and lower levels of inflammatory cytokines following NK-cell infusion. Intriguingly, despite omission of systemic IL2, all patients displayed increased frequencies of activated Ki-67&lt;sup&gt;+&lt;/sup&gt;CD127&lt;sup&gt;−&lt;/sup&gt;FoxP3&lt;sup&gt;+&lt;/sup&gt;CD25&lt;sup&gt;hi&lt;/sup&gt;CD4&lt;sup&gt;+&lt;/sup&gt; Treg cells of recipient origin following NK-cell therapy.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusions:&lt;/b&gt; Overall, this study suggests that high-risk MDS is responsive to NK-cell therapy and supports the use of haploidentical NK-cell infusions as a bridge to HSCT in refractory patients. Objective clinical responses and reduction of high-risk clones were associated with detectable donor-derived NK cells, immunoediting of residual blast cells, and less pronounced host immune activation. &lt;i&gt;Clin Cancer Res; 24(8); 1834–44. ©2018 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;
Mechanisms of ultrasound foam interactions (2009)

Abstract An experimental investigation into the effects of two frequencies of low‐power ultrasound on detergent (Teepol) stabilised air‐water foams is presented. Foam was subjected to ultrasound at 28 and 40 kHz with a power‐to‐foam volume ratio of approximately 3 W l −1 with particular consideration being given to the acoustic impedance discontinuity between air and water. The foam height, liquid drainage and collapse behaviour were compared to experiments conducted without ultrasound. In the case of 40 kHz ultrasound, an increased liquid drainage rate was observed and a pronounced increase and subsequent peak in mean liquid hold‐up, which occurred at 4 min, was observed. These results appear to be independent of the initial liquid hold‐up of the foam. Liquid drainage and mean liquid hold‐up results were related to foam collapse mechanisms of homogeneous rupture (HR) and rupture front breakage (FR), concluding that rupture front breakage dominates the collapse of foam under the influence of 40 kHz ultrasound. Copyright © 2009 Curtin University of Technology and John Wiley &amp; Sons, Ltd.
First Optically Active Molecular Electronic Wires (2006)

[structure: see text]. The optically active molecular electronic wires (S)- and (R)-7 containing an oligo-arylene-ethynylene structure and a chiral 1,1'-binaphthyl unit are synthesized. These molecules are incorporated into nanowell devices by self-assembly on the gold surface. In the nanowell devices, the median currents from the molecules containing both S and R enantiomers are significantly smaller than those from the pure S or R molecule. Compounds (R)- and (S)-7 are also less conductive than the fully conjugated oligo-phenylene-ethynylene-thiol molecules.
ISOFLURANE-ENHANCED RECOVERY OF CANINE STUNNED MYOCARDIUM (1999)

Introduction: Isoflurane (ISO) has previously been shown to enhance the recovery of stunned myocardium via activation of adenosine A1-receptors and adenosine triphosphate-regulated potassium (KATP) channels. The role of protein kinase C (PKC) as an important mediator of the cardioprotective signal transduction mechanism elicited by isoflurane in the recovery of stunned myocardium is unknown. Therefore, we tested the hypothesis that inhibition of PKC using the specific PKC antagonist, bisindolylmaleimide I (BIS), antagonizes the action of ISO to enhance recovery of stunned myocardium. Methods: Dogs (n = 49) were randomly assigned to pretreatment with intracoronary drug vehicle (VEH) or BIS (2 or 8 [micro sign]g[center dot]min-1) in the presence or absence of ISO (1 MAC). VEH or BIS, with or without ISO, were administered 30 min prior to and during 5 brief (5 min) coronary artery occlusions interspersed with 5 min reperfusion periods, followed by a final 3 hr of reperfusion. ISO, VEH or BIS were discontinued at the onset of final reperfusion. Hemodynamics, regional segment shortening (SS) and myocardial blood flow (radioactive microspheres) were measured at selected intervals before and during coronary artery occlusions and reperfusions in the presence and absence of ISO. Data were analyzed within and between groups using multiple analysis of variance for repeated measures followed by application of Student's t-test with Bonferroni's correction. Results: There were no differences in baseline hemodynamics, SS, myocardial perfusion of normal regions or coronary collateral blood flow between groups. Coronary artery occlusion decreased mean arterial blood pressure, dp/dtmax and increased left ventricular end diastolic pressure in all groups. ISO decreased mean arterial pressure, heart rate and dp/dtmax to a similar extent in the presence or absence of BIS. Sustained contractile dysfunction was observed in VEH-pretreated dogs (SS recovered to 18 +/- 9% of baseline) after 3 hr of reperfusion. In contrast, dogs receiving ISO + VEH demonstrated enhanced (* p<0.05 vs. VEH alone) recovery of contractile function to 74 +/- 7% of baseline. BIS, at dose that was selective for PKC (2[micro sign]g[center dot]min-1), did not attenuate the cardioprotective effects of ISO. However BIS, at a higher nonselective dose (8[micro sign]g[center dot]min-1), blocked the ISO-enhanced recovery of SS (Figure 1).Figure 1Conclusions: The results indicate that PKC activation plays a minor role during ISO-induced cardioprotection because BIS, at a dose specific for PKC-inhibition, did not attenuate ISO-induced recovery of SS. The contribution of other pathways or specific isoforms of PKC to ISO-induced cardioprotection remains to be investigated.
Determination of the Reaction Zone in Gadolinia-Doped Ceria Anode for Solid Oxide Fuel Cell (2008)

In order to elucidate the reaction zone in porous anodes on yttria-stabilized zirconia (YSZ), ac impedance and steady-state polarization measurements are carried out in gas mixtures with different electrode thicknesses, 7, 20, and anodes. Steady-state polarization current becomes larger as the electrode becomes thicker, while the current per unit surface area shows similar value. Therefore, the current seems to be a function of the electrode surface area. In ac impedance measurements, an extremely large pseudo-capacitance is observed to be as large as . The measured pseudo-capacitance is caused by the nonstoichiometric perturbation of the oxygen content in the anode material. Both steady-state polarization and ac impedance measurements suggest that the reaction zone extends from the interface of YSZ/porous anodes toward the outer gas phase. The distribution of electrochemically active zone is semiquantitatively estimated. The activity for the surface reaction gradually decreases with increasing the distance from the electrode/electrolyte interface, and the reduction rate of the activity becomes high as the electrode thickness increases.