gebhart/patrepeval huggingface dataset:
Object Data Management: Object-Oriented and Extended Relational Database Systems (1991)

(All chapters, excepts Chapters 1 and 8, begin with an Introduction.) Preface. 1. Introduction. Need for Object Data Management. Data Models and Database Architectures. Object Data Management Concepts. 2. Advanced Database Applications. Software Engineering. Mechanical and Electrical Design. Documents and Office Applications. Other Applications. Conclusions. 3. Traditional Database Systems. Database Concepts. Relational Databases. Query Languages. Storing Relations. Access Methods. Query Processing. Concurrency and Recovery. Distributed Databases. Application Tools. Performance. Summary. 4. Object Data Management Concepts. Objects. Relationships. Composite Objects. Procedures. Types and Inheritance. Query and Programming Languages. Persistence, Concurrency, and Recovery. Other Topics. Summary. 5. Implementation Issues. Object Storage. Relationships. Composite Objects and Clustering. Procedures and Programming Languages. Object Types. Query Processing. Concurrency and Recovery. Distribution. Performance. Summary. 6. Future Database Systems. ODMG. ODMG C++. SQL3. Other Standards Activities. Summary. 7. Goals for Object Data Management. Database Functionality. Objects and Properties. Type System. Programming and Query Languages. Database Architecture. Other Issues. Summary. 8. Conclusions. Needs for Object Data Management. Object Data Management Approaches. Future Directions. Summary. Appendix: Products and Prototypes. Introduction. Object-Oriented Database Systems. Extended Relational Database Systems. Extended Functional and Semantic Database Systems. Database System Generators. Object Managers. Summary. System Bibliography. Annotated Bibliography. Index. 0201547481T04062001
Effect of ionic conduction under dielectric barriers on PEDOT:PSS electrochemical interfaces (2021)

Abstract Poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) has been widely used for electrochemical interfaces. When the surface is covered by an inhomogeneous dielectric layer, ions are injected to the uncovered part of PEDOT:PSS and then laterally diffuse to the covered part. However, this effect has not been incorporated into the device model. Here we show the effect of lateral ionic diffusion on the transient response of electrochemical interfaces. When PEDOT:PSS is partially covered by a dielectric layer, the covered part contributes to the electrochemical admittance unlike metal electrodes. This effect also makes the transient performance of organic electrochemical transistors deviate from conventional models.
European training network on full-parallax imaging (Conference Presentation) (2017)

Current displays are far from truly recreating visual reality. This requires a full-parallax display that can reproduce radiance field emanated from the real scenes. The develop-ment of such technology will require a new generation of researchers trained both in the physics, and in the biology of human vision. The European Training Network on Full-Parallax Imaging (ETN-FPI) aims at developing this new generation. Under H2020 funding ETN-FPI brings together 8 beneficiaries and 8 partner organizations from five EU countries with the aim of training 15 talented pre-doctoral students to become future research leaders in this area. In this contribution we will explain the main objectives of the network, and specifically the advances obtained at the University of Valencia.
[Asymmetry of visual perceptive activity of faces and emotional facial expressions]. (1989)

Eye movements were studied in 40 right-handed subjects during perception of symmetrical chimerical faces. These movements were recorded using an original system based on a differential optical method for the detection of corneal reflection and of the pupil made shiny. Under basal conditions, the first fixation was usually located in the left visual hemifield. The subjects spent more time gazing at the right hemiface (P less than 0.04). This visuo-spatial asymmetry in favour of the left hemispace was increased when the subject was requested to determine the emotional expressions of a new series of faces (P less than 0.002). Compared with basal conditions, the increase in the percentage of time spent in the left area was significant (P less than 0.035). An analysis performed on the first 3 seconds confirmed and amplified the differences observed. These results can partly be explained by reading habits and exploratory activity for symmetrical shapes. However, activation of the right hemisphere, specialized in the perception of faces and facial expressions, probably influenced visual exploration by drawing attention to the left area and favouring the left visual hemifield.
Initial Reaction Probability and Dynamics of Ozone Collisions with a Vinyl-Terminated Self-Assembled Monolayer (2011)

The gas–surface reaction dynamics of ozone with a model unsaturated organic surface have been explored through a series of molecular beam scattering experiments. Well-characterized organic surfaces were reproducibly created by adsorption of C═C-terminated long-chain alkanethiols onto gold, while the incident molecular beams were created by supersonic expansion of ozone seeded in an inert carrier gas to afford control over collision energy. Time-of-flight distributions for the scattered molecules showed near complete thermal accommodation of ozone for incident energies as high as 70 kJ/mol. Reflection–absorption infrared spectroscopy, performed in situ with ozone exposure, revealed that oxidation of the double bond depends significantly on the translational energy of O3. For energies near room temperature, 5 kJ/mol, the initial reaction probability (γ0) for the formation of the primary ozonide was determined to be γ0 = 1.1 × 10–5. As translational energy increased to 20 kJ/mol, the reaction probability decreased. This behavior, along with a strong inverse relationship between γ0 and surface temperature, demonstrates that the room-temperature reaction follows the Langmuir–Hinshelwood mechanism, requiring accommodation prior to reaction under nearly all atmospherically relevant conditions. However, measurements show that the dynamics transition to a direct reaction (analogous to the Eley–Rideal mechanism) for elevated translational energies.
Combination of t(14;18) and a Burkitt's Type Translocation in B-cell Malignancies (1993)

The combination of chromosomal translocations associated with bcl-2 rearrangement [t(14;18)] and c-myc rearrangement [t(8;14), t(8;22), or t(2;8)] has infrequently been detected in lymphoproliferative disorders. We have recently identified four cases of a B-cell malignancy exhibiting this dual translocation. In addition to t(14;18), one case had t(8;14) and three had the t(8;22). One case presented as de novo acute lymphoblastic leukemia (ALL-L2), two as de novo high grade lymphomas and the fourth evolved to a "blastic" phase from a previously documented follicular lymphoma. Immunophenotyping and molecular analysis was performed on three of the cases: all were negative for terminal deoxynucleotidyl transferase (TdT) but were CD10 positive. Two of the three cases with t(8;22) were negative for surface immunoglobulin (SIg) and positive for HLA-DR. Rearrangement of the oncogene bcl-2 was identified in a single case by polymerase chain reaction (PCR) only. Similar to cases reported in the literature, all patients had a poor clinical outcome despite aggressive therapy. Dual translocation lymphoid malignancy has a relatively characteristic morphology and the diagnosis should be considered when there is a history of an antecedent low grade lymphoma or when there is discordance between the "blastic" morphology and the immunophenotype (TdT- and/or SIg+). Confirmation requires demonstration of the characteristic translocations. Recognition of this entity has significant clinical implications that may require consideration of alternate treatment strategies.
A 700-kb physical map of a region of 16q23.2 homozygously deleted in multiple cancers and spanning the common fragile site FRA16D. (2000)

We have identified a >600-kb region at 16q23.2 that is homozygously deleted from malignant ovarian ascites using representational difference analysis. Overlapping homozygous deletions were also observed in the colon carcinoma cell line HCT116 and a xenograft established from the small cell lung cancer cell line WX330. This region coincides with that described previously by others as showing loss of heterozygosity in prostate and breast cancers (C. Li et al., Genes Chromosomes Cancer, 24: 175-182, 1999; A. Latil et al., Cancer Res., 57: 1058-1062, 1997; K. Driouch et al., Genes Chromosomes Cancer, 19: 185-191, 1997; A. Iida et al., Br. J. Cancer, 75: 264-267, 1997). In addition, the minimally deleted region spans the common fragile site FRA16D. We have constructed a 700-kb physical map encompassing the deleted region. By fluorescence in situ hybridization of aphidicolin-induced metaphase chromosomes, we have preliminary data to suggest that P1-derived bacterial artificial chromosome clones from the contig lie on both sides of FRA16D. This is confirmed by extensive fluorescence in situ hybridization analysis of the region reported in the accompanying article (M. Mangelsdorf et al., Cancer Res., 60: 1683-1689, 2000) and is consistent with an involvement of this common fragile site in the loss of 16q23.2 material in various cancer types. The minimally deleted region of approximately 210 kb has been characterized using our own markers and public domain markers. Eleven distinct expressed sequences mapped to the region, providing a basis for identifying the predicted tumor suppressor gene in this region.
Ki-67 is a prognostic parameter in breast cancer patients: results of a large population-based cohort of a cancer registry (2013)

The proliferation marker Ki-67 is one of the most controversially discussed parameters for treatment decisions in breast cancer patients. The purpose of this study was to evaluate the routine use and value of Ki-67 as a prognostic marker, and to analyze the associations between Ki-67 and common histopathological parameters in the routine clinical setting. Data from the clinical cancer registry Regensburg (Bavaria, Germany) were analyzed. Within the total data pool of 4,692 female patients, who had been diagnosed between 2005 and 2011, in 3,658 cases Ki-67 was routinely determined. Thus, a total of 3,658 patients with invasive breast cancer were included in the present study and used for statistical analysis. Ki-67 expression was associated with the common histopathological parameters. The strongest correlation was found between grading and Ki-67 (P < 0.001). In terms of survival analyses, Ki-67 was categorized into five categories (reference category Ki-67 ≤15 %) due to a nonlinear relationship to overall survival (OS). In multivariable analysis, Ki-67 was an independent prognostic parameter both for disease-free survival (DFS) (Ki-67 > 45 %, HR = 1.96, P = 0.001) as well as for OS (Ki-67: 26-35 %, HR = 1.71, P = 0.017; Ki-67: 36-45 %, HR = 2.05, P = 0.011; Ki-67 > 45 %, HR = 2.06, P = 0.002) independent of common clinical and histopathological factors. The 5-year DFS (OS) rate was 86.7 % (89.3 %) in patients with a Ki-67 value ≤15 % compared to 75.8 % (82.8 %) in patients with a Ki-67 value >45 %. Based on the data from a large cohort of a clinical cancer registry, it was demonstrated that Ki-67 is frequently determined in routine clinical work. Ki-67 expression is associated with common histopathological parameters, but is an additional independent prognostic parameter for DFS and OS in breast cancer patients. Future work should focus on standardization of Ki-67 assessment and specification of its role in treatment decisions.
ChemInform Abstract: Natural Products. Antitubulin Effect of Congeners of N‐Acetylcolchinyl Methyl Ether: Synthesis of Optically Active 5‐ Acetamidodeaminocolchinyl Methyl Ether and of Demethoxy Analogues of Deaminocolchinyl Methyl Ether. (1993)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Some New Developments in Centrifugal Partiton Chromatography and Applications in the Separation of Natural Products (1990)

Abstract A two-pump method for the control of stationary to mobile phase ratios in a cartridge centrifugal partition chromatography system is described. This cartridge CPC set-up and a rotating coil instrument are used in the separation of natural products from complex mixtures contained in crude plant extracts.
Age and Positional Effect on the Anterior Chamber Angle: Assessment by Ultrasound Biomicroscopy (2013)

Purpose. To investigate age- and position-related changes of anterior chamber angle anatomy in normal, healthy eyes. Patients and Methods. Thirty subjects were separated into a younger and older cohort. The superior and inferior anterior chamber angles of the eyes were measured in supine and sitting positions by ultrasound biomicroscopy (UBM) with bag/balloon technology. Statistical analysis was used to evaluate positional and age-related changes in angle morphology. Results. In the younger cohort, no location or positional differences in angle anatomy were observed. In the older cohort, the inferior quadrant was significantly narrower than the superior quadrant (P = 0.0186) in the supine position. This cohort also demonstrated an interaction effect between position and location. In the older cohort, the angle was deeper inferiorly while the subject was sitting but was deeper superiorly while the subject was supine. Conclusion. Comparison of positional variations in anterior chamber angle anatomy as measured by UBM has recently become possible. This study found that age-related positional changes in the anterior chamber angle anatomy exist in normal healthy eyes.
Robust flux weakening scheme for surface-mounted permanent-magnet synchronous drives employing an adaptive lattice-structure filter (1999)

An advanced control structure for surface-mounted permanent-magnet synchronous (SMPMS) drives provides a stable, high performance operation in the flux weakening region, utilizing the over-modulation and six-step modes of the space vector modulation (SVM). An automatic transition into flux weakening is achieved by controlling the reference voltage magnitude. The fifth and seventh stator current harmonics of the fundamental frequency, generated in the over-modulation and six-step modes, propagate through the current control loops, resulting in the sixth harmonic in the reference voltage and deteriorating drive performance. To filter the sixth harmonic, an adaptive lattice-structure allpass-based notch filter is employed, providing minimal phase delay and complete attenuation of the sixth harmonic.
Techniques to resect the distal ureter in robotic/laparoscopic nephroureterectomy (2016)

Treatment of clinically-organ confined high grade urothelial carcinoma of the upper tract has historically comprised open nephroureterectomy, with the distal ureter and bladder cuff mobilized through a separate open pelvic incision. To decrease morbidity, urologists have increasingly adopted laparoscopy and robotics in performing nephroureterectomy. In many published series of laparoscopic nephroureterectomy, the distal ureter and bladder cuff are detached from the bladder endoscopically by a variation of the “pluck” technique, with the resulting bladder defect left to heal by prolonged indwelling urethral catheter drainage. While the distal ureter and bladder cuff can be excised laparoscopically, it does require advanced laparoscopic skills. With the wrist articulation and stereoscopic vision in robotic surgery, robotic nephroureterectomy (RNU) and bladder cuff excision can be performed in antegrade fashion to mimic the open technique together with the ability to intracorporeally close the bladder defect in a watertight, mucosa to mucosa fashion after excising the bladder cuff. In this review, we discuss the published minimally invasive techniques in resecting the distal ureter and bladder cuff during laparoscopic and RNU.
A comparison of moderate fat (MF) and high fat (HF) diets enriched with purified resistant starch or resistant starch in the form of whole grain flour in rats (2015)

Whole grain (WG) and fat content of the diet was previously shown to affect intestinal fermentation and phenotype conferred by high-amylose maize starch (RS), a form of fermentable dietary fiber. T...
Effect of Different Heating Process on the Photoluminescence Properties of Perovskite Eu-Doped BaZrO3 Powder (2016)

In this study, BaZrO3:Eu0.025 powder was synthesized through the solid-state reaction method with two different heating processes. For the one-step process, the BaZrO3:Eu0.025 powder was heated to 1000 °C–1400 °C for 2 h. For the two-step heating process, the BaZrO3:Eu0.025 powder was pre-heated at 800 °C for 2 h, after being cooled to room temperature and ground, then the powder was heated to 1000 °C–1400 °C again for 2 h. The optimum excitation optical wavelength of BaZrO3:Eu0.025 powders were 271 nm and the maximum intensity of the emission spectrum of BaZrO3:Eu0.025 powders increased with increasing heating temperature. The all-heated BaZrO3:Eu0.025 powders showed two strong orange emission bands peaking at the wavelengths of 574 and 596 nm and two weak emission bands peaking at 620 and 650 nm. As the heating temperatures were 1300 °C and 1400 °C, the maximum intensity of one-step heating BaZrO3:Eu0.025 powders appeared at the 5D0–7F0 (574 nm) and the maximum intensity of one-step heating BaZrO3:Eu0.025 powders appeared at the 5D0–7F1 (596 nm) transitions of Eu3+ ions, respectively.
Comparative Wavefront Sensing for a Space Based Segmented Aperture Telescope (1999)

The success of phase retrieval on the Hubble Space Telescope (HST) [1][2][3][4][5] led us to consider phase retrieval as a possible method of wavefront sensing for future large space telescopes. Phase retrieval can be used in an active optical control loop as the fine figure sensor by utilizing the science cameras with little or no additional optical hardware but with an increase in either on-board or ground based computer processing. We show some initial results of our hierarchical optical control loop and discuss our on-going study. Segmented Aperture Space Telescopes Possible large scale space based astronomical imaging telescopes, such as the Next Generation Space Telescope (NGST) [6][7] will most likely be a large (~8 meter diameter aperture) operating at least over the wavelength band 1.0 to 5.0 microns and required to be diffraction limited (l/14). The size and weight constraints for this class of telescope dictate that the primary mirror (PM) be a lightweight multi-segmented m...
Exosomal TAR DNA binding protein 43 profile in canine model of amyotrophic lateral sclerosis: a preliminary study in developing blood-based biomarker for neurodegenerative diseases (2022)

Serum-derived exosomal biomolecules can serve as surrogate biomarkers in neurodegenerative diseases.KEY MESSAGESA canine with degenerative myelopathy can serve as a model animal to study human amyotrophic lateral sclerosis.Serum-derived exosomes contain Transactive Response DNA Binding Protein 43 (TDP-43), a potential biomarker candidate.The levels of spinal cord TDP-43 proteins and that of serum-derived exosomes exhibited similar profiling. Therefore, serum derived exosomes may be used as a venue for establishing blood-based biomarkers for neurodegenerative diseases.
Recent advances in understanding norovirus pathogenesis (2016)

Noroviruses constitute a family of ubiquitous and highly efficient human pathogens. In spite of decades of dedicated research, human noroviruses remain a major cause of gastroenteritis and severe diarrheal disease around the world. Recent findings have begun to unravel the complex mechanisms that regulate norovirus pathogenesis and persistent infection, including the important interplay between the virus, the host immune system, and commensal bacteria. Herein, we will summarize recent research developments regarding norovirus cell tropism, the use of M cells, and commensal bacteria to facilitate norovirus infection, and virus, host, and bacterial determinants of persistent norovirus infections. J. Med. Virol. 88:1837-1843, 2016. © 2016 Wiley Periodicals, Inc.
Identification of conserved amino acids in the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit critical for function. Evidence for formation of a heterodimeric receptor complex prior to ligand binding. (1994)

A superfamily of growth factor and cytokine receptors has recently been identified, which is characterized by four spatially conserved cysteine residues, a tryptophan-serine motif (WSXWS) in the extracellular domain, and a proline-rich cytoplasmic domain. The high affinity human granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor (hGM-CSFR) consists of two subunits, alpha (hGM-CSFR alpha) and beta (hGM-CSFR beta), both of which are members of the receptor superfamily. In this study, we prepared mutations in conserved amino acids of the receptor subunit necessary for GM-CSF binding (hGM-CSFR alpha) and analyzed mutant receptors for low affinity binding, internalization, and high affinity binding when complexed with the beta subunit. Mutations in the cytoplasmic domain did not affect GM-CSF binding or receptor internalization. Mutation of a single conserved serine residue within the WSXWS motif diminishes cell surface receptor expression but not ligand binding. Mutation of either the second or third conserved cysteine residue of hGM-CSFR alpha resulted in complete loss of low affinity binding; however, co-expression of the cysteine 2 mutant with hGM-CSFR beta yielded a high affinity receptor complex. Since neither the cysteine 2 mutant nor the beta subunit can bind ligand alone, this result suggests that hGM-CSFR alpha and hGM-CSFR beta exist in a preformed heterodimeric protein complex on the plasma membrane.
Preparation of Microporous Polypropylene Membrane via Thermally Induced Phase Separation as Support of Liquid Membranes Used for Metal Ion Recovery. (2003)

Microporous polypropylene (PP) membranes were prepared by the thermally induced phase separation (TIPS) technique and used as supports of liquid membranes. Several different quenching temperatures were used in the preparation of the microporous membranes. Membranes prepared by air-cooling and quenching in a water bath of 353 K showed higher porosity at the membrane surface compared with those made by quenching in a water bath of 303 K and in ice-water. A simplified one-dimensional heat transfer equation was solved to evaluate the temperature profile within the membrane to demonstrate the effect of quenching temperature on the final pore size distribution. The calculated result suggested that the asymmetric membrane structure formed by quenching in 303 K water and ice-water was not attributable to the temperature gradient.Supported liquid membranes (SLMs) were prepared by impregnating a carrier solution in the prepared porous polypropylene membranes, and uphill transport of Ce(III) was investigated using octyl(phenyl)-N,N-diisobutyl-carbamoyl-methylphosphine oxide (CMPO) as a carrier, tributyl phosphate (TBP) as a modifier, and dodecane as a solvent. The membranes prepared by air-cooling showed higher permeability of Ce(III) than the commercial membrane.