gebhart/patrepeval huggingface dataset:
Genetic Effects Conferring Heat Tolerance in a Cross of Tolerant × Susceptible Maize (Zea mays L.) Genotypes (2016)

Incessant rise in ambient temperature is threatening sustainability of maize productions, worldwide. Breeding heat resilient synthetics/hybrids is the most economical tool while lack of knowledge of gene action controlling heat and yield relevant traits in maize is hampering progress in this regard. The current study, therefore, was conducted using analyses of generation mean and variance, and narrow sense heritability ([Formula: see text]) and genetic advance as percent of mean (GAM%). Initially, one hundred inbred lines were evaluated for cell membrane thermo-stability and grain yield per plant on mean day/night temperatures of 36.6°C/22.1°C in non-stressed (NS) and 42.7°C/25.7°C in heat-stressed (HS) conditions. From these, one tolerant (ZL-11271) and one susceptible (R-2304-2) genotypes were crossed to develop six basic generations, being evaluated on mean day/night temperatures of 36.1°C/22.8°C (NS) and 42.3°C/25.9°C (HS) in factorial randomized complete block design with three replications. Non-allelic additive-dominance genetic effects were recorded for most traits in both conditions except transpiration rate, being controlled by additive epistatic effects in NS regime. Dissection of genetic variance into additive (D), dominance (H), environment (E) and interaction (F) components revealed significance of only DE variances in HS condition than DE, DFE and DHE variances in NS regime which hinted at the potential role of environments in breeding maize for high temperature tolerance. Additive variance was high for majority of traits in both environments except ear length in NS condition where dominance was at large. Higher magnitudes of [Formula: see text] [Formula: see text] and GAM% for cell membrane thermo-stability, transpiration rate, leaf firing, ear length, kernels per ear and grain yield per plant in both regimes implied that simple selections might be sufficient for further improvement of these traits. Low-to-moderate GAM% for leaf temperature and 100-grain weight in both conditions revealed greater influence of genotype-environment interactions, indicating ineffective direct selection and advocating for further progeny testing. In conclusion, pyramiding of heritable genes imparting heat tolerance in maize is achievable through any conventional breeding strategy and generating plant material with lowest cellular injury and leaf firing, and higher transpiration rate, ear length, kernels per ear and grain yield per plant.
A Prioritized Cache for Multi- tasking Real-time Systems (2004)

This study examined the prevalence, counts, and subtypes of Campylobacter, Salmonella, Listeria monocytogenes, verotoxigenic Escherichia coli (VTEC), and E. coli on raw retail chicken breast with the skin on versus the skin off. From January to December 2007, 187 raw skin-on chicken breasts and 131 skin-off chicken breasts were collected from randomly selected retail grocery stores in the Region of Waterloo, Ontario, Canada. Campylobacter isolates were recovered from a higher proportion of the skin-off chicken breasts, 55 (42%) of 131, than of the skin-on chicken breasts tested, 55 (29%) of 187 (P = 0.023). There was no difference in the proportion of Salmonella isolates recovered from the two meat types (P = 0.715): 40 (31%) of 131 skin-off chicken breasts versus 61 (33%) of 187 skin-on chicken breasts. L. monocytogenes isolates were recovered from a statistically lower proportion of the skin-off chicken breasts, 15 (15%) of 99, than of the skin-on chicken breasts, 64 (34%) of 187 (P = 0.001). There was no difference in the proportion of E. coli isolates recovered from the skin-off chicken breasts, 33 (33%) of 99, than from the skin-on chicken breasts, 77 (41%) of 187 (P = 0.204). VTEC was detected on a single skin-off chicken breast. Campylobacter jejuni was the most frequent species isolated on both types of chicken meat: skin-on, 48 (87%) of 55, and skin-off, 51 (94%) of 54. Salmonella serotypes Kentucky and Heidelberg and L. monocytogenes serotype 1/2a were the most frequently detected serotypes from both skin-off and skin-on chicken breasts. Although there appeared to be a trend toward higher enumeration values of these pathogens and E. coli on the skin-on chicken, the differences did not exceed 1 log. This study suggested that skin-off chicken breast may represent a higher risk of consumer exposure to Campylobacter, a similar risk for Salmonella, VTEC, and E. coli, and a lower risk for L. monocytogenes than skin-on chicken breast.
Passage through resonance of two coupled exciters (2021)

Abstract A minimal model of two coupled exciters is considered to investigate passage through resonance of self‐synchronizing systems. An averaging method for partially strongly damped systems [1] is used for asymptotic analysis. Stationary solutions of the system is derived and compared with previous work [2]. The dependency of such solutions on damping and excitation power is shown.
Gastrointestinal Adverse Events after Dual Antiplatelet Therapy: Clopidogrel Is Safer than Ticagrelor, but Prasugrel Data Are Lacking or Inconclusive (2013)

Current guidelines offer a choice of P2Y12 receptor antagonist among clopidogrel, prasugrel or ticagrelor on top of aspirin (ASA) for dual antiplatelet therapy (DAPT) in patients after acute coronary syndromes (ACS). However, the comparative risks of gastrointestinal (GI) adverse events during DAPT are not clear. Two large ACS trials (TRITON and PLATO) provide a valuable opportunity to directly match the risks of GI complications among current antiplatelet regimens. We compared the rates of GI adverse events after prasugrel and ticagrelor versus clopidogrel based on the Food and Drug Administration (FDA) clinical safety reviews. When compared with ticagrelor, clopidogrel is safer with regard to GI-related risks including fewer overall GI/anal bleeding events and spontaneous GI hemorrhagic episodes, less nausea, vomiting, dyspepsia and diarrhea, and a lower rate of presence of Helicobacter pylori. Among GI symptoms, only constipation was more common after clopidogrel than following ticagrelor. There were extrahepatic risks observed with ticagrelor but not with prasugrel when compared to clopidogrel. Prasugrel unquestionably caused more bleeding from the GI tract and GI malignancies than clopidogrel. However, the entire spectrum of GI effects of prasugrel is much less well known and mostly based on sponsor analysis rather than FDA-verified numbers. Among 3 DAPT options on top of ASA, clopidogrel seems to represent the safest alternative, although comprehensive data on direct prasugrel-associated GI effects are lacking or inconclusive.
Clickable Gold Nanoparticles as the Building Block of Nanobioprobes (2010)

A new method of fabricating "clickable" gold nanoparticles that could be used as the building block of nanobioprobes was described. On the basis of a well-developed strategy of encapsulating hydrophobic nanoparticles with a layer of amphiphilic polymers, cheap, easily prepared graft polymer was used as a modifier to prepare monodisperse azide-functionalized gold nanoparticles (AuNPs), which showed good stability in physiological solution. By conjugation with alkyne functional horseradish peroxidase (HRP) via click chemistry under mild conditions, the azide-AuNPs have demonstrated their potential in the fabrication of stable, bioactive nanobioprobes. Some critical problems in the fabrication of nanobioprobes, such as how to detect the number of bound biomolecules on nanoparticles and evaluate the bioactivities of nanobioprobes, are discussed in detail.
The role of selected factors in the development and consequences of alcohol dependence. (2008)

Gender, family history, comorbid psychiatric and substance use disorders, and age all influence a person's risk for alcoholism. In addition, these factors interact with alcoholism to influence neurocognitive functioning following detoxification. This article examines these factors and considers how they interact with each other. This complexity reinforces the need for both animal and human studies and suggests multiple factors that may be sensitive to differential prevention, intervention, and treatment efforts. Thus, it is imperative that hypothesis-driven research designs be directed to identifying the relative potency of these factors and their interactions.
Ramp-rate limitation test of cable-in-conduit conductors with supercritical helium (1995)

It has been found on the United States Demonstration Poloidal Coil (US-DPC) and in 27 strand subsized cables of pool boiling cable-in-conduit conductor (CICC), that there is critical current degradation due to fast ramping of the magnetic field. The characteristics of this ramp-rate limitation phenomenon are investigated by using a 27 strand Nb/sub 3/Sn cable in supercritical helium at 6 atm. A 3 m long cable-in-conduit conductor is prepared noninductively and tested in a background field up to 9.5 tesla with maximum ramp rate of 1.6 tesla/second. The ramp-rate limitation results are compared with results of the ramp rate test of the US-DPC and previous experiments. The experimental data are analyzed to identify and understand possible sources of ramp-rate limitation.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
A machine-learning classifier implemented in a standard 6T SRAM array (2016)

This paper presents a machine-learning classifier where the computation is performed within a standard 6T SRAM array. This eliminates explicit memory operations, which otherwise pose energy/performance bottlenecks, especially for emerging algorithms (e.g., from machine learning) that result in high ratio of memory accesses. We present an algorithm and prototype IC (in 130nm CMOS), where a 128×128 SRAM array performs storage of classifier models and complete classifier computations. We demonstrate a real application, namely digit recognition from MNIST-database images. The accuracy is equal to a conventional (ideal) digital/SRAM system, yet with 113× lower energy. The approach achieves accuracy >95% with a full feature set (i.e., 28×28=784 image pixels), and 90% when reduced to 82 features (as demonstrated on the IC due to area limitations). The energy per 10-way digit classification is 633pJ at a speed of 50MHz.
Oxytocin and carbetocin ameliorating effects on restraint stress-induced short- and long-term behavioral changes in rats. (2010)

Repeated restraint stress exposure produced acute and persisting effects on Wistar rat behavior in the OF and EPM tests. CBT either injected before or after stress practically abolished the developed changes in the mobility parameters. The CBT effectiveness to ameliorate the late post-stress behavioral alteration supports the notion of its therapeutic potential in psychiatric disorders in which the role of OXY has been implicated.
Motion adaptation against environmental changes based on self-evaluation (2010)

We suggest motion adaptation method against environmental changes for service robots. Several motions such as walking, dancing, demonstration and so on are described with time series patterns. These motions are optimized with the architecture of the robot and under certain surrounding environment. Under unknown environment, robots cannot accomplish their tasks. We propose motion generation system based on heuristic search with histories of internal sensor values. New motion patterns are explored under unknown environment based on self-evaluation function. Self-evaluation function is composed of difference of internal sensor values between standard environment and unknown environment. New motion patterns are generated to maximize self-evaluation function without external information, such as run length, position of robot, human observation and so on. Experimental results show that the possibility to adapt autonomously patterned motions to environmental changes.
Amyotrophic lateral sclerosis (ALS)-associated VAPB-P56S inclusions represent an ER quality control compartment (2013)

The data indicate that the VAPB-P56S inclusions represent a novel reversible ER quality control compartment that is formed when the amount of mutant VAPB exceeds the capacity of the ERAD pathway and that isolates misfolded and aggregated VAPB from the rest of the ER. The presence of this quality control compartment reveals an additional level of flexibility of neurons to cope with misfolded protein stress in the ER.
Oral Flecainide Pharmacokinetics in Patients with Impaired Renal Function (1988)

The pharmacokinetics of flecainide acetate were studied in 20 patients with varying degrees of renal impairment following a single oral dose. The patients were divided into two groups, on the basis of renal creatinine clearance (CLCR), for statistical and kinetic analysis. Patients with a CLCR between 4 and 41 mL/min/m2 were designated group 1 and those below 4 mL/min/m2 or unmeasurable because of lack of urine output were designated group 2. In both groups peak plasma flecainide concentrations, time to peak concentrations, and apparent volume of distribution (Vd) were similar to those reported in healthy subjects with normal renal function. The mean flecainide plasma elimination half-lives from both groups 1 and 2 were longer than those previously reported by several investigators in normal subjects. Nine patients in group 1 and seven patients in group 2 had half-lives within the range reported in healthy subjects. Therefore, CLCR alone is not a good predictor of plasma elimination half-life following a single oral dose of flecainide. Although renal clearance of flecainide is significantly reduced in end-stage renal disease (ESRD), total plasma clearance of flecainide (CLflec) was not reduced to the same degree, although there was a significant, modest correlation with CLCR. Less than 1% of the administered oral dose of flecainide was removed during hemodialysis. The relationship between dosage and plasma elimination half-life in patients with ESRD needs further study to evaluate possible dose-dependent kinetics.
Real-time high-definition stereo matching on FPGA (2011)

Although many fast stereo matching designs have been proposed in the past decades, it is still very challenging to achieve real-time speed at high definition resolution while maintaining high matching accuracy. In this paper, we propose a real-time high definition stereo matching design on FPGA. By using the Mini-Census transform and the Cross-based cost aggregation, the proposed algorithm is robust to radiometric differences and produces accurate disparity maps. The algorithm modules have been optimized for efficient hardware implementations and instantiated in an SoC environment. Implemented on a single EP3SL150 FPGA, our design achieves 60 frames per second for 1024 × 768 stereo images. Evaluated with the Middlebury stereo benchmark, the proposed design also delivers leading stereo matching accuracy among prior related work.
Catalytic Asymmetric Reduction of a 3,4-Dihydroisoquinoline for the Large-Scale Production of Almorexant: Hydrogenation or Transfer Hydrogenation? (2013)

Several methods are presented for the enantioselective synthesis of the tetrahydroisoquinoline core of almorexant (ACT-078573A), a dual orexin receptor antagonist. Initial clinical supplies were secured by the Noyori Ru-catalyzed asymmetric transfer hydrogenation (Ru-Noyori ATH) of the dihydroisoquinoline precursor. Both the yield and enantioselectivity eroded upon scale-up. A broad screening exercise identified TaniaPhos as ligand for the iridium-catalyzed asymmetric hydrogenation with a dedicated catalyst pretreatment protocol, culminating in the manufacture of more than 6 t of the acetate salt of the tetrahydroisoquinoline. The major cost contributor was TaniaPhos. By switching the dihydroisoquinoline substrate of the Ru-Noyori ATH to its methanesulfonate salt, the ATH was later successfully reduced to practice, delivering several hundreds of kilograms of the tetrahydroisoquinoline, thereby reducing the catalyst cost contribution significantly. The two methods are compared with regard to green and efficiency metrics.
MULTIDISCIPLINARY BIOLOGY TRAINING ‐ Undergraduate Student Perspective (2010)

Majority of undergraduate students in biology prospect themselves toward a career in medical professions. However, biology is a vibrant discipline and a degree in biology prepares for careers in many other professions with opportunities in a wide range of fields. Therefore, it is imperative that undergraduate biology students are prepared to recognize the potential of biology background. A key factor in this preparation is an extensive curriculum that integrates contemporary, multidisciplinary concepts so that graduates become aware of issues in a number of fields and feel empowered with their knowledge. This also is critical to building student confidence and eliminating postgraduation uncertainty. Another key factor is the engagement of students in laboratory activities. Hands‐on technical exercises cultivate students’ capacity to work cooperatively, multitask, manage time and resources, and think about how concepts and applications are related. Finally, students feel stimulated when collaborations and interactions between students are nurtured since such an educational setting generates positive experience with greater sense of belonging. In conclusion, it is important that undergraduate biology students acknowledge the broad prospects of the bachelor's degrees in biology and the importance of multidisciplinary training in realizing the potential of biology in the 21 st century.
Will surface effects dominate in quasi-two-dimensional gallium oxide for electronic and photonic devices? (2019)

The ultra-wide band gap semiconductor Ga<sub>2</sub>O<sub>3</sub> has advantages for power electronics applications in the automotive industry, data center power management and industrial systems but attention must be paid to its surface sensitivity to the environment.
Macromol. Theory Simul. 5/2010 (2010)

Cover: The image represents results of 3D modeling of mesoscopic phases adopted by amphiphilic lipids at air-water interfaces. The cylindrical, lamellar, and hybrid structures demonstrate the predicted morphologies for saturated lipids. The graph represents a non-uniform quasi-2D distribution of the lipids within the quasi-planar micelles. Further details can be found in the article by K. Poulose Santo, A. Kovalenko, and M. Stepanova* on page 228.
Flow cytometric analysis of DNA ploidy and S-phase fraction in breast cancer using cells obtained by ex vivo fine-needle aspiration: an optimal method for sample collection. (1991)

A total of 203 primary invasive breast cancers were sampled by ex vivo fine-needle aspiration (FNA), directly yielding adequate single cell suspensions for flow cytometric DNA analysis in 194 (96%). Labor-intensive and time-consuming steps of mechanical and enzymatic cellular disaggregation required by the use of fresh, frozen, or paraffin-embedded tissue were avoided, thereby minimizing preparation time. Conservation of tumor tissue allowed for the sampling of very small breast cancers. DNA ploidy and S-phase fraction data were comparable to flow cytometric data reported in other breast cancer studies using various sampling methods. Ex vivo FNA is the easiest and fastest method for sampling breast cancers for flow cytometric DNA analysis.
Detecting volunteer cotton plants in a corn field with deep learning on UAV remote-sensing imagery (2022)

Volunteer cotton (VC) plants growing in the fields of inter-seasonal and rotated crops, like corn, can serve as hosts to boll weevil pests once they reach pin-head square stage (5–6 leaf stage). The VC plants therefore need to be detected, located, and destroyed or sprayed. In this paper, we present a study on using deep learning (DL) to detect VC plants in a corn field using RGB images collected with an unmanned aerial vehicle (UAV). The objectives were (i) to determine whether the YOLOv3 DL algorithm could be used for VC detection in a corn field based on UAV-derived RGB images, and (ii) to investigate the behavior of YOLOv3 on images at three different pixel scales (320 × 320, S1; 416 × 416, S2; and 512 × 512, S3). The metrics used to evaluate the results were average precision (AP), mean average precision (mAP) and F1-score at 95 % confidence level. It was found that YOLOv3 was able to detect VC plants in corn field at an average detection accuracy of more than 80 %, F1-score of 78.5 % and mAP of 80.38 %. With respect to images size, no significant differences existed for mAP among the three scales, but a significant difference was found for AP between S1 and S3 (p = 0.04) and between S2 and S3 (p = 0.02). A significant difference was also found for F1-score between S2 and S3 (p = 0.02). The overall goal of this study was to minimize boll weevil pest infestation by maximizing the true positive detection of VC plants in a corn field which is represented by the mAP values. The lack of significant differences of these at all three scales indicated that the trained YOLOv3 model can be used for VC detection irrespective of the three input image sizes. The capability of YOLOv3 to detect VC plants demonstrates the potential of DL algorithms for real-time detection and mitigation using computer vision and a spot-spray capable UAV.
P17-10. A new AuxoGTU-HIV B DNA vaccine induce very long lasting HIV specific T cells response which is efficiently boosted with HIV LAI lipopeptides (2009)

DOAJ is a unique and extensive index of diverse open access journals from around the world, driven by a growing community, committed to ensuring quality content is freely available online for everyone.
A Novel Random Key Algorithm in Wireless Sensor Networks (2008)

Based on existing problems of security in wireless sensor networks, this paper analyzes the resistance against capture, network connectivity extending and memory overhead among random key pre-distribution schemes, q-composite pre-distribution schemes and symmetric key algorithm. A novel random key algorithm is proposed combining random and authentication. Finally, the algorithm is compared with any other algorithm. The simulation results show that the algorithm is superior to others in security and feasibility.
Coherent control of magnon radiative damping with local photon states (2019)

Abstract A magnon, the collective excitation of ordered spins, can spontaneously radiate a travelling photon to an open system when decaying to the ground state. However, in contrast to electric dipoles, magnetic dipoles by magnons are more isolated from the environment, limiting their radiation and coherent communication with photons. The recent progresses in strongly coupled magnon-photon system have stimulated the manipulation of magnon radiation via tailoring the photon states. Here, by loading an yttrium iron garnet sphere in a one-dimensional waveguide cavity supporting both the travelling and standing photon modes, we demonstrate a significant magnon radiative damping that is proportional to the local density of photon states (LDOS). By modulating the magnitude and/or polarization of LDOS, we can flexibly tune the photon emission and magnon radiative damping. Our findings provide a way to manipulate photon emission from magnon radiation, which could help harness angular momentum generation, transfer, and storage in magnonics.