gebhart/patrepeval huggingface dataset:
FFR-Aided Coordinated Multipoint Transmission in Downlink Multicell MIMO-OFDMA Networks (2015)

Fractional frequency reuse (FFR) is an intercell interference coordination technique that has become increasingly popular in the context of 4G systems. The combination of FFR with advanced multiple-antenna technology in the form of multiuser MIMO (MU-MIMO) and base station cooperation using coordinated multipoint transmission (CoMP), paves the way to realize the ambitious goals in terms of area spectral efficiency contemplated within Long Term Evolution Advanced (LTE-A). This work proposes an FFR-aided scheme suitable for multicell networks in which central users are served using MU-MIMO and edge users rely on CoMP, with both techniques depending on block diagonalization. A physical layer abstraction is provided in the form of signal-to-interference-plus- noise ratio (SINR) expressions that can then be used to derive optimal values for different parameters, most notably, the threshold SINR delimiting the central and edge areas of the cell.
Formation of methional and methanethiol from methionine (1972)

Abstract Methanethiol is formed from methionine and sulphite in a reaction catalysed by iron or manganous ions. Methionine sulphoxide and dimethyl disulphide are other products of the reaction. Methional [3‐(methylthio)propional] is postulated as an intermediate in the reaction.
Approaches to isozyme-specific inhibitors. 16. A novel methyl-C5' covalent adduct of L-ethionine and .beta.,.gamma.-imido-ATP as a potent multisubstrate inhibitor of rat methionine adenosyltransferases (1989)

N6,N6-Dibenzoyl-2',3'-O-isopropylideneadenosine, which is readily synthesized by one-pot 5'-O-trimethylsilylation, N6-benzoylation, and desilylation, was converted to the corresponding 5'-aldehyde. This was treated with CH2 = CHMgBr to afford, after debenzoylation, a 1:3 mixture of the 5'S and 5'R epimers, respectively, of 5'-C-vinyl-2',3'-O-isopropylideneadenosine. The configurations were established by single-crystal X-ray diffraction analysis of the 5'R epimer. Hydroboration of the 5'-O-tetrahydropyranyl derivative of the mixed epimeric 5'-C-vinyl nucleosides readily furnished 5'(S,R)-C-(2-hydroxyethyl)-2',3'-O-isopropylideneadenosine. Treatment of the 5'(S,R)-C-(2-O-tosyl) derivative of this with disodium L-homocysteinate permitted facile introduction of the L-ethionine system. By means of methods developed earlier in the synthesis of homologous methionine-ATP adducts, the alpha-amino acid group was protected, a beta,gamma-imidotriphosphoryl group was introduced at O5', and blocking groups were removed to give the title adduct as a 2:3 mixture of its two 5' epimers. It was a powerful inhibitor [KM(ATP)/Ki = 520 and 340] of the M-2 (normal tissue) and M-T (hepatoma tissue) forms, respectively, of the title enzyme and displayed predominantly competitive kinetics with the two substrates L-methionine and MgATP. It inhibited M-2 and M-T slightly less effectively than its homologue possessing one less CH2 between sulfur and C5' and gave kinetic evidence of an increased tendency to form L-methionine-enzyme-adduct and MgATP-enzyme-adduct complexes.
Synthesis of 2S-Dioxo Isosteres of Purine and Pyrimidine Nucleosides IV. Selective Glycosylation of 4-Amino-5H-Imidazo [4, 5-c]-1, 2, 6-Thiadiazine 2, 2-Dioxide (1987)

Abstract Selective glycosylation of 4-amino-5H-imidazo [4, 5-c]-1, 2, 6-thiadiazine 2, 2-dioxide (1) through its 1-benzyl derivative (2) is described. The structures of the compounds are discussed on the basis of 1H nmr 2D homonuclear chemical shift correlations, NOE difference spectroscopy and iterative analyses.
North Carolina Medicaid Recipient Management Lock-In Program: The Pharmacist’s Perspective (2014)

Although possible improvements were identified, the NC MLIP has strong potential for success as it utilizes pharmacists' medication gate-keeping role, while minimizing the effort required for successful implementation.
Session details: OOPSLA onward! track Chair's welcome (2006)

No abstract available.
BULB: A Unified Lexical Browser. (2006)

Natural language processing researchers currently have access to a wealth of information about words and word senses. This presents problems as well as resources, as it is often difficult to search through and coordinate lexical information across various data sources. We have approached this problem by creating a shared environment for various lexical resources. This browser, BULB (Brandeis Unified Lexical Browser) and its accompanying front-end provides the NLP researcher with a coordinated display from many of the available lexical resources, focusing, in particular, on a newly developed lexical database, the Brandeis Semantic Ontology (BSO). BULB is a module-based browser focusing on the interaction and display of modules from existing NLP tools. We discuss the BSO, PropBank, FrameNet, WordNet, and CQP, as well as other modules which will extend the system. We then outline future extensions to this work and present a release schedule for BULB. 1.
Functional characterization of LFA-1 antigens in the interaction of human NK clones and target cells. (1985)

In the present studies we analyzed the role of LFA-1 antigens in the interaction between NK clones and target cells. The use of various cloned NK cell lines allowed us to analyze homogeneous populations of NK cells which ordinarily comprise only a small fraction of peripheral blood lymphocytes and are extremely heterogeneous with respect to phenotype and specificity. Indirect immunofluorescence with monoclonal antibodies against the alpha (MHM24) and beta (MHM23) chains of the LFA-1 antigen revealed similar patterns of positive reactivity with all NK clones. Both monoclonal antibodies exerted a significant blocking effect on NK cytotoxicity against target cells such as Molt-4 and CEM, whereas the inhibition was very weak against other targets such as K562 and HSB cells. Additive blocking effects were seen when both monoclonal antibodies MHM23 and MHM24 were added to the cytotoxicity assays. When we compared the inhibitory effect of MHM23 and MHM24 on uncultured peripheral blood NK cells and IL 2-activated NK cells, inhibition of cytotoxicity also was found to be primarily dependent on the individual target cells. Thus, the inhibitory activity of anti-LFA-1 antibody was shown to be independent of the phenotypic and functional heterogeneity of the NK clones, activated NK cells, and unstimulated NK cells utilized in these studies. These blocking effects were found to be independent of the LFA-1 antigen expression on the target cell membrane and inhibition occurred only when antibody was bound to the effector cells. Comparison of the effects of anti-LFA-1, anti-T3, and anti-clonotypic antibodies against a Ti-like structure of different NK clones with a mature T cell phenotype demonstrated that each of these antibodies acts on the effector cells in an independent and additive fashion. However, unlike T3 and NKTa antigen, LFA-1 antigen expression is not modulated by cell surface interaction with antibodies specific for this molecule.
Flow Analysis and Optimization for Membrane Oxygenators (2013)

中空糸膜を使用した膜型人工肺内部の流体解析および最適化を行い，人工肺内部の流れの様子を検討した．最適化に関しては，Robust設計の手法の一つである多目的遺伝アルゴリズムを用いて高性能化のために3つの目的関数を設定し，処理を行った．目的関数は，流れを均一にすること，低流速の部位を最小にすること，小型にすることとした。基準となる人工肺モデルから，最適化を進め約1000世代分の計算を行った。計算では，パレート最適解が得られその中から適切と思われるものを選択し，実際に試作を行った。血液を使用した評価の結果，最適化を行ったものは，初期形状のものに比較して小型化が行え，酸素移動量で18．4％，炭酸ガス移動量で４０％以上の改善が図られた。解析の結果，中空糸膜（ガス交換膜）束に如何に均一に血液を導くかが重要であることが判り，その形状の方向性を得ることができた。
Candida albicans FRE8 encodes a member of the NADPH oxidase family that produces a burst of ROS during fungal morphogenesis (2017)

Until recently, NADPH oxidase (NOX) enzymes were thought to be a property of multicellularity, where the reactive oxygen species (ROS) produced by NOX acts in signaling processes or in attacking invading microbes through oxidative damage. We demonstrate here that the unicellular yeast and opportunistic fungal pathogen Candida albicans is capable of a ROS burst using a member of the NOX enzyme family, which we identify as Fre8. C. albicans can exist in either a unicellular yeast-like budding form or as filamentous multicellular hyphae or pseudohyphae, and the ROS burst of Fre8 begins as cells transition to the hyphal state. Fre8 is induced during hyphal morphogenesis and specifically produces ROS at the growing tip of the polarized cell. The superoxide dismutase Sod5 is co-induced with Fre8 and our findings are consistent with a model in which extracellular Sod5 acts as partner for Fre8, converting Fre8-derived superoxide to the diffusible H2O2 molecule. Mutants of fre8Δ/Δ exhibit a morphogenesis defect in vitro and are specifically impaired in development or maintenance of elongated hyphae, a defect that is rescued by exogenous sources of H2O2. A fre8Δ/Δ deficiency in hyphal development was similarly observed in vivo during C. albicans invasion of the kidney in a mouse model for disseminated candidiasis. Moreover C. albicans fre8Δ/Δ mutants showed defects in a rat catheter model for biofilms. Together these studies demonstrate that like multicellular organisms, C. albicans expresses NOX to produce ROS and this ROS helps drive fungal morphogenesis in the animal host.
Enabling Solar Fuels Technology By High Throughput Discovery of Earth Abundant Oxygen Evolution Reaction Catalysts (2015)

The High Throughput Experimentation (HTE) project of the Joint Center for Artificial Photosynthesis performs accelerated discovery of new earth-abundant photoabsorbers and electrocatalysts. We will describe several new screening instruments for high throughput (photo-)electrochemical measurements and summarize the discovery pipelines. This approach will be illustrated using the high throughput discovery, follow-on verification, and device implementation of a new quaternary metal oxide catalyst. Discovering improved electrocatalysts for the oxygen evolution reaction (OER) is of great importance for efficient solar fuels generation, regenerative fuel cells, and recharging metal air batteries. We report a new Ce-rich family of active catalysts composed of earth abundant elements, which was discovered using high-throughput methods to produce 5456 discrete compositions in the (Ni-Fe-Co-Ce)Ox composition space. The activity and stability of this new OER catalyst was verified by re-synthesis and extensive electrochemical testing of samples in a standard format in 1.0 M NaOH. Characterization of selected compositions by XRD, XPS, SEM, TEM, EDS, XRF mapping, and EXAFS both as-synthesized and after electrochemical testing, reveal the important of nanostructure to the observed electrochemical performance. The discovery of additional electrocatalysts by expansion of this composition space investigated and of new composition spaces tested for OER activity and stability under acidic conditions will be reported.
Optical diode based on the chirality of guided photons (2015)

Photons are nonchiral particles: their handedness can be both left and right. However, when light is transversely confined, it can locally exhibit a transverse spin whose orientation is fixed by the propagation direction of the photons. Confined photons thus have chiral character. Here, we employ this to demonstrate nonreciprocal transmission of light at the single-photon level through a silica nanofibre in two experimental schemes. We either use an ensemble of spin-polarised atoms that is weakly coupled to the nanofibre-guided mode or a single spin-polarised atom strongly coupled to the nanofibre via a whispering-gallery-mode resonator. We simultaneously achieve high optical isolation and high forward transmission. Both are controlled by the internal atomic state. The resulting optical diode is the first example of a new class of nonreciprocal nanophotonic devices which exploit the chirality of confined photons and which are, in principle, suitable for quantum information processing and future quantum optical networks.
Apocynin-Treatment Reverses Hyperoxaluria Induced Changes in NADPH Oxidase System Expression in Rat Kidneys: A Transcriptional Study (2012)

A strong up-regulation of an oxidative/respiratory burst involving the NADPH oxidase system, activated via the angiotensin-II and most likely the DAG-PKC pathways, occurs in kidneys of hyperoxaluric rats. Apocynin treatment reversed this activation without affecting the levels of hyperoxaluria.
Microwave phase noise properties of optical links involving small signal and gain saturated optical amplifiers (2014)

International audience
A Maximum A Posteriori Probability Viterbi Data Association Algorithm for Ball Tracking in Sports Video (2006)

In this paper, we derive a data association algorithm for object tracking in a maximum a posteriori framework: the output of the algorithm is the sequence of measurement-to-target associations with maximum a posteriori probability. We model the object motion as a Markov process, and solve this otherwise combinatorially complex problem efficiently by applying the Viterbi algorithm. A method for combining forward and backward tracking results is also developed, to recover from tracking errors caused by abrupt motion changes of the object. The proposed algorithm is applied to broadcast tennis video to track a tennis ball. Experiments show that its performance is comparable to that of a computationally more expensive particle-filter-based algorithm
<title>Statistical investigations of multiscale image structure (Proceedings Only)</title> (1992)

This artificial visual system (AVS) is a computational framework for computer vision based on spatial filtering and statistical pattern recognition. Computer vision tasks are often poorly defined; the AVS clarifies the kinds of visual tasks that can be defined and what constitutes a well-defined task. `Segmentation'' is not a well-defined task. Edge detection is revealed to be an absurd task. A filter set composed of multiscale Gaussians alone captures the structure of Koenderink''s generic neighborhood operators when a pattern is constructed from the responses at a pixel and neighboring locations, where the distance to the selected neighbors increases with larger scale. Prior studies of the feature space formed by multiscale Gaussians reveal surprising power in the multiscale Gaussians alone. New studies support this observation. Contrary to common belief, we show how nonlocal, spatial, geometric structure can be captured using statistical pattern recognition operations in the AVS framework. A procedure is defined for deriving a single composite filter providing optimal separation of two clusters in feature space.
Capacitance of Basal Plane and Edge-Oriented Highly Ordered Pyrolytic Graphite: Specific Ion Effects (2019)

Carbon materials are ubiquitous in energy storage; however, many of the fundamental electrochemical properties of carbons are still not fully understood. In this work, we studied the capacitance of highly ordered pyrolytic graphite (HOPG), with the aim of investigating specific ion effects seen in the capacitance of the basal plane and edge-oriented planes of the material. A series of alkali metal cations, from Li<sup>+</sup>, Na<sup>+</sup>, K<sup>+</sup>, Rb<sup>+</sup>, and Cs<sup>+</sup> with chloride as the counterion, were used at a fixed electrolyte concentration. The basal plane capacitance at a fixed potential relative to the potential of zero charge was found to increase from 4.72 to 9.39 μF cm<sup>-2</sup> proceeding down Group 1. In contrast, the edge-orientated samples display capacitance ca. 100 times higher than those of the basal plane, attributed to pseudocapacitance processes associated with the presence of oxygen groups and largely independent of cation identity. This work improves understanding of capacitive properties of carbonaceous materials, leading to their continued development for use in energy storage.
Analysis of Secondary-Loop Refrigeration Systems Using Carbon Dioxide as a Volatile Secondary Refrigerant (1996)

Abstract A secondary-loop refrigeration system, using ammonia in the primary-loop and carbon dioxide as a volatile secondary refrigerant, was investigated as an alternative system for supermarkets. Ammonia and carbon dioxide are naturally occurring substances which have zero ozone depletion and zero effective global warming potential. The use of these natural refrigerants provides a long-term solution to environmental problems associated with refrigeration. Generalized computer models for the analysis of secondary-loop and conventional refrigeration systems were developed in order to evaluate the feasibility of the secondary-loop system. A description of these models is presented along with results showing the potential of the secondary-loop system. The results indicate that this system can provide a cost effective alternative.
Exact Interpolation of Apodized, Magnitude-Mode Fourier Transform Spectra (1989)

A procedure is developed for the exact interpolation of apodized, magnitude-mode Fourier transform (FT) spectra. The procedure gives the true center frequency, i.e., the location of the continuous peak, from just the largest three discrete intensities in the discrete magnitude spectrum. The procedure is applicable for the peaks in the apodized magnitude spectrum of a time signal of the form f( t) = cos( ωt) exp(– t/τ). There are no restrictions on the value of the damping ratio T/τ. The procedure is demonstrated for the sine-bell and Hanning windows and is generalizable to other windows which consist of a sum of constants and sine/cosine terms. This includes the majority of commonly used windows.
A Platform for Collaborative Acoustic Signal Processing (2005)

In this paper, we present a platform for collaborative acoustic signal processing, and demonstrate its use with an example application. Our platform is built upon the Stargate Linux-based microserver, and supports synchronized multi-channel acoustic data acquisition. We implement a dataflow-like staged event-driven programming model within the Emstar software framework that simplifies the development of collaborative processing applications. Unlike previous dataflow systems that emphasize real-time constraints, our framework emphasizes collaborative processing across nodes in a distributed system connected by an energy-conserving wireless network with non-deterministic message latency. In our model, an application is constructed by wiring together multiple stages, where each stage is implemented by an EmStar module. The modular approach simplifies development by isolating errors to specific stages, and enables run-time systemreconfigurability by allowing users to swap out implementations of individual stages, and to reconfigure the dataflow at run time.
ChemInform Abstract: The Didemnins: Biological Properties, Chemistry and Total Synthesis (1993)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Probing dynamics of complex molecular systems with ultrafast 2D IR vibrational echo spectroscopy (2007)

Ultrafast 2D IR vibrational echo spectroscopy is described and a number of experimental examples are given. Details of the experimental method including the pulse sequence, heterodyne detection, and determination of the absorptive component of the 2D spectrum are outlined. As an initial example, the 2D spectrum of the stretching mode of CO bound to the protein myoglobin (MbCO) is presented. The time dependence of the 2D spectrum of MbCO, which is caused by protein structural evolution, is presented and its relationship to the frequency-frequency correlation function is described and used to make protein structural assignments based on comparisons to molecular dynamics simulations. The 2D vibrational echo experiments on the protein horseradish peroxidase are presented. The time dependence of the 2D spectra of the enzyme in the free form and with a substrate bound at the active site are compared and used to examine the influence of substrate binding on the protein's structural dynamics. The application of 2D vibrational echo spectroscopy to the study of chemical exchange under thermal equilibrium conditions is described. 2D vibrational echo chemical exchange spectroscopy is applied to the study of formation and dissociation of organic solute-solvent complexes and to the isomerization around a carbon-carbon single bond of an ethane derivative.
Initial ventricular activation in left-sided intraventricular conduction defects. (1980)

Nine patients with ECG evidence of rate-related left bundle branch block (LBBB) were studied using His bundle electrograms, electrograms from the right ventricular (RV) apex and vectorcardiograms recorded as heart rate was increased to produce LBBB. In five patients, when LBBB occurred, initially normal septal activation reversed and the HV intervals increased 10-30 msec, while the H-RVA interval did not change (group 1). Four patients had initially normal QRS duration (90-100 msec) but reversed septal activation (group 2). When LBBB developed there was no shift in either the HV interval or H-RVA interval. Only the QRS complex itself widened to distinguish these patients from group 1. These studies defined ventricular septal activation in normal conduction and in complete LBBB (group 1) and incomplete LBBB (group 2). The conduction patterns of group 1 and 2 patients are similar but are both markedly different from normal.
High-Intensity Focused Ultrasound Ablation of Rabbit Kidney Tumors (1996)

High-intensity focused ultrasound (HIFU) is a noninvasive surgical technique in which ultrasound energy is delivered transcutaneously to a discrete area within the body. This energy can result in a well-defined zone of cellular death within the targeted tissue. We used HIFU in an effort to ablate rabbit VX-2 kidney tumors. A tumor cell suspension was injected into a renal segmental artery (Phase 1, nine rabbits) or directly into the lower pole parenchyma (Phase 2, nine rabbits). After a 2-week incubation period, open direct contact (Phase 1) or transcutaneous ablation (Phase 2) was performed. In Phase 1, after sonablation, there was pathologic evidence of tissue destruction in nine animals, and seven had both gross and histologic evidence of tumor ablation. There was sharp demarcation between viable and ablated tissue. In Phase 2, pathologic evidence of kidney ablation was seen in seven of nine animals. However, only two rabbits showed the well-demarcated effects of ablation in the tumor. High-intensity focused ultrasound can be effective at causing cell death in renal tumors and surrounding renal tissue. However, with the present ultrasound technology, imaging of renal lesions in the rabbit model is not adequate to consistently localize and completely ablate tumor.