gebhart/patrepeval huggingface dataset:
Perl and Apache: Your visual blueprint for developing dynamic Web content (2010)

Visually explore the range of built-in and third-party libraries of Perl and Apache. Perl and Apache have been providing Common Gateway Interface (CGI) access to Web sites for 20 years and are constantly evolving to support the ever-changing demands of Internet users. With this book, you will heighten your knowledge and see how to usePerl and Apache to develop dynamic Web sites. Beginning with a clear, step-by-step explanation of how to install Perl and Apache on both Windows and Linux servers, you then move on to configuring each to securely provide CGI Services. CGI developer and author Adam
Determination of Ethylenediaminetetraacetic Acid as Chromium Complex (1954)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDetermination of Ethylenediaminetetraacetic Acid as Chromium ComplexP. J. Cherney, Barbara. Crafts, H. H. Hagermoser, A. J. Boule, Ray. Harbin, and Bennie. ZakCite this: Anal. Chem. 1954, 26, 11, 1806–1809Publication Date (Print):November 1, 1954Publication History Published online1 May 2002Published inissue 1 November 1954https://pubs.acs.org/doi/10.1021/ac60095a035https://doi.org/10.1021/ac60095a035research-articleACS PublicationsRequest reuse permissionsArticle Views71Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Characteristics of Microencapsulated Palm-Based Oil as Affected by Type of Wall Material (1996)

Microcapsules containing a blend of red palm olein (red POo) and refined, bleached and deodorised palm stearin (RBD POs) in the ratio of 60:40 were prepared with various wall materials using a spray-drying technique. The total oil content of the microcapsules ranged from 398 to 683·2gkg−1. Surface oil and moisture content varied from 38·8 to 158·9gkg−1 and 25 to 30gkg−1, respectively. Carotene retention after spray-drying and after storage depended on the oil content and types of wall materials, and ranged from 194·65 to 215·28 and 158·8 to 203·1mgkg−1, respectively. Microcapsules with the best characteristics were made from wall material containing proteinaceous material.
Designing a Smart Transfer Patient Bed (2015)

In the hospital, nurses need to transfer a paralyse patient from medical bed to others places, such as x-ray laboratory, MRI laboratory, another ward and others. Normally two nurses are needed to transfer the patient. The task becomes more challenging when transferring an overweight patient. The nurses will experience a musculoskeletal disorder (MSDS) including back injuries in the long run. If the task is carried out frequently, most likely the nurses will experience a chronic back pain. Smart Transfer Patient Bed is designed to solve the nurses' problems in transferring patient. The aim of the product is to assist the nurse to transfer the patient from the warded bed to the medical bed so that the nurse can bring the patient to another location. The main concept of this product is to move the patient slowly and smoothly. A linear actuator and ball transfers are used as the main components to transfer the patient. The linear actuator is used to pull and push the moving platform. While the ball transfers are used to reduce the friction when the platform is moving. Smart Transfer Patient Bed can support a patient with maximum weight of 150 kg. The main frame of this product was made by using an aluminium profile. During the assembly process, the platform could not move in on a straight line smoothly. After some modifications were made, the platform could move on straight line smoothly and safely.
The Influence of Plant Density and Shoot Pruning on Yield of Bell Pepper Cultivated in Plastic Tunnel (2010)

The aim of the experiment effectuated at the company SC Cristal Lux SRL from Balan commune, Salaj County, Romania, was to establish the best plant density and plant directing method for bell peppers cultivated in plastic tunnel. A bifactorial experience has been organized: Factor A = plant density, with: a1– 30000 plants/ha; a2– 40000 plants/ha; Factor B = shoots pruning method, with: b1– pruned with 2 shoots; b2– pruned with 3 shoots. By factors combination 4 experimental variants resulted. Plants density has affected both the early and the total yield. A density of 40000 plants/ha assured a significant yield increase comparative with 30000 plants/ha. The pruning method has influenced neither early nor total yield. Under the combined influenced of both factors the best results have been obtained by variant III (40000 plants/ha, 2 shoots) and variant IV (40000 plants/ha, 3 shoots) for both the early and the total yield.
Correction of a Cystic Fibrosis Splicing Mutation by Antisense Oligonucleotides (2015)

Cystic fibrosis (CF), the most common life-threatening genetic disease in Caucasians, is caused by ∼2,000 different mutations in the CF transmembrane conductance regulator (CFTR) gene. A significant fraction of these (∼13%) affect pre-mRNA splicing for which novel therapies have been somewhat neglected. We have previously described the effect of the CFTR splicing mutation c.2657+5G>A in IVS16, showing that it originates transcripts lacking exon 16 as well as wild-type transcripts. Here, we tested an RNA-based antisense oligonucleotide (AON) strategy to correct the aberrant splicing caused by this mutation. Two AONs (AON1/2) complementary to the pre-mRNA IVS16 mutant region were designed and their effect on splicing was assessed at the RNA and protein levels, on intracellular protein localization and function. To this end, we used the 2657+5G>A mutant CFTR minigene stably expressed in HEK293 Flp-In cells that express a single copy of the transgene. RNA data from AON1-treated mutant cells show that exon 16 inclusion was almost completely restored (to 95%), also resulting in increased levels of correctly localized CFTR protein at the plasma membrane (PM) and with increased function. A novel two-color CFTR splicing reporter minigene developed here allowed the quantitative monitoring of splicing by automated microscopy localization of CFTR at the PM. The AON strategy is thus a promising therapeutic approach for the specific correction of alternative splicing.
The effect of triacylglycerol fatty acid positional distribution on postprandial plasma metabolite and hormone responses in normal adult men (1994)

The present study has examined the possibility that the positional distribution of fatty acids on dietary triacyglycerol (TAG) influences the postprandial response to a liquid meal in adult subjects. Postprandial TAG, non-esterified fatty acids (NEFA), ketones, glucose, insulin and gastric inhibitory polypeptide (GIP) responses were monitored in sixteen normal adult male subjects over 6 h following consumption of test meals containing dietary TAG in which palmitic acid was predominantly on the sn-1 (Control) or sn-2 positions (Betapol). Plasma total TAG, chylomicron-rich TAG and chylomicron-poor TAG concentrations were identical in response to the two test meals. The peak increase (mean (SD)) in chylomicron TAG was 0.85 (0.46) mmol/l after the Control meal and 0.85 (0.42) mmol/l after the Betapol meal. Plasma glucose, insulin, GIP, NEFA and ketone concentrations were also very similar following the two meals. It is concluded that dietary TAG containing saturated fatty acids on the sn-2 position appear in plasma at a similar level and over a similar timescale to TAG in which saturated fatty acids are predominantly located on sn-1 or sn-3 positions. The results reported in the present study demonstrate that the positional distribution of fatty acids on dietary TAG is not an important determinant of postprandial lipaemia in adult male subjects, but do not exclude the possibility that different responses may occur when these dietary TAG are given long term.
Controlling Electromagnetic Fields (2006)

Using the freedom of design that metamaterials provide, we show how electromagnetic fields can be redirected at will and propose a design strategy. The conserved fields-electric displacement field D, magnetic induction field B, and Poynting vector B-are all displaced in a consistent manner. A simple illustration is given of the cloaking of a proscribed volume of space to exclude completely all electromagnetic fields. Our work has relevance to exotic lens design and to the cloaking of objects from electromagnetic fields.
LWPR: A Scalable Method for Incremental Online Learning in High Dimensions (2005)

Locally weighted projection regression (LWPR) is a new algorithm for incremental nonlinear function approximation in high dimensional spaces with redundant and irrelevant input dimensions. At its core, it employs nonparametric regression with locally linear models. In order to stay computationally efficient and numerically robust, each local model performs the regression analysis with a small number of univariate regressions in selected directions in input space in the spirit of partial least squares regression. We discuss when and how local learning techniques can successfully work in high dimensional spaces and compare various techniques for local dimensionality reduction before finally deriving the LWPR algorithm. The properties of LWPR are that it i) learns rapidly with second order learning methods based on incremental training, ii) uses statistically sound stochastic leave-one-out cross validation for learning without the need to memorize training data, iii) adjusts its weighting kernels based only on local information in order to minimize the danger of negative interference of incremental learning, iv) has a computational complexity that is linear in the number of inputs, and v) can deal with a large number of- possibly redundant- inputs, as shown in various empirical evaluations with up to 50 dimensional data sets. For a probabilistic interpretation, predictive variance and confidence intervals are derived. To our knowledge, LWPR is the first truly incremental spatially localized learning method that can successfully and efficiently operate in very high dimensional spaces. 1
Productive Infection of Neonatal CD8+ T Lymphocytes by HIV-1 (1998)

CD8+ T lymphocytes confer significant but ultimately insufficient protection against HIV infection. Here we report that activated neonatal CD8+ T cells can be productively infected in vitro by macrophage-tropic (M-tropic) HIV-1 isolates, which are responsible for disease transmission, whereas they are resistant to T cell-tropic (T-tropic) HIV strains. Physiological activation of CD8-alpha/beta+ CD4- T cell receptor-alpha/beta+ neonatal T cells, including activation by allogeneic dendritic cells, induces the accumulation of CD4 messenger RNA and the expression of CD4 Ag on the cell surface. The large majority of anti-CD3/B7.1-activated cord blood CD8+ T cells coexpress CD4, the primary HIV receptor, as well as CCR5 and CXCR4, the coreceptors used by M- and T-tropic HIV-1 strains, respectively, to enter target cells. These findings are relevant to the rapid progression of neonatal HIV infection. Infection of primary HIV-specific CD8+ T cells may compromise their survival and thus significantly contribute to the failure of the immune system to control the infection. Furthermore, these results indicate a previously unsuspected level of plasticity in the neonatal immune system in the regulation of CD4 expression by costimulation.
Identification and characterization of a novel structural glycoprotein in pseudorabies virus, gL (1994)

Herpesvirus envelope glycoproteins play important roles in the interaction between virions and target cells. In the alphaherpesvirus pseudorabies virus (PrV), seven glycoproteins that all constitute homologs of glycoproteins found in herpes simplex virus type 1 (HSV-1) have been characterized, including a homolog of HSV-1 glycoprotein H (gH). Since HSV-1 gH is found associated with another essential glycoprotein, gL, we analyzed whether PrV also encodes a gL homolog. DNA sequence analysis of a corresponding part of the UL region adjacent to the internal inverted repeat in PrV strains Kaplan and Becker revealed the presence of two open reading frames (ORF). Deduced proteins exhibited homology to uracil-DNA glycosylase encoded by HSV-1 ORF UL2 (54% identity) and gL encoded by HSV-1 ORF UL1 (24% identity), respectively. To identify the PrV UL1 protein, rabbit antisera were prepared against two synthetic oligopeptides that were predicted by computer analysis to encompass antigenic epitopes. Sera against both peptides reacted in Western blots of purified virions with a 20-kDa protein. The specificity of the reaction was demonstrated by peptide competition. Since the PrV UL1 sequence did not reveal the presence of a consensus N-linked glycosylation site, concanavalin A affinity chromatography and enzymatic deglycosylation of virion glycoproteins were used to ascertain that the PrV UL1 product is O glycosylated. Therefore, we designated this protein PrV gL. Analysis of mutant PrV virions lacking gH showed that concomitantly with the absence of gH, gL was also missing in purified virions. In summary, we identified and characterized a novel structural PrV glycoprotein, gL, which represents the eighth PrV glycoprotein described. In addition, we show that virion location of PrV gL is dependent on the presence of PrV gH.
Elastomeric polypropylenes from alumina-supported tetraalkyl Group IVB catalysts. 1. Synthesis and properties of high molecular weight stereoblock homopolymers (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElastomeric polypropylenes from alumina-supported tetraalkyl Group IVB catalysts. 1. Synthesis and properties of high molecular weight stereoblock homopolymersJohn W. Collette, Charles W. Tullock, Robert N. MacDonald, Warren H. Buck, Aaron C. L. Su, Jerald R. Harrell, Rolf Mulhaupt, and Burton C. AndersonCite this: Macromolecules 1989, 22, 10, 3851–3858Publication Date (Print):October 1, 1989Publication History Published online1 May 2002Published inissue 1 October 1989https://pubs.acs.org/doi/10.1021/ma00200a006https://doi.org/10.1021/ma00200a006research-articleACS PublicationsRequest reuse permissionsArticle Views295Altmetric-Citations95LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Transfer function analysis of dynamic cerebral autoregulation: A CARNet white paper 2022 update (2022)

Cerebral autoregulation (CA) refers to the control of cerebral tissue blood flow (CBF) in response to changes in perfusion pressure. Due to the challenges of measuring intracranial pressure, CA is often described as the relationship between mean arterial pressure (MAP) and CBF. Dynamic CA (dCA) can be assessed using multiple techniques, with transfer function analysis (TFA) being the most common. A 2016 white paper by members of an international Cerebrovascular Research Network (CARNet) that is focused on CA strove to improve TFA standardization by way of introducing data acquisition, analysis, and reporting guidelines. Since then, additional evidence has allowed for the improvement and refinement of the original recommendations, as well as for the inclusion of new guidelines to reflect recent advances in the field. This second edition of the white paper contains more robust, evidence-based recommendations, which have been expanded to address current streams of inquiry, including optimizing MAP variability, acquiring CBF estimates from alternative methods, estimating alternative dCA metrics, and incorporating dCA quantification into clinical trials. Implementation of these new and revised recommendations is important to improve the reliability and reproducibility of dCA studies, and to facilitate inter-institutional collaboration and the comparison of results between studies.
Spectrophotometric and Electrochemical Study of Gold‐Iodide in Aqueous Borate Medium (1996)

The constant‐current electrolysis technique was utilized to determine the oxidation state of gold in iodide media. The products from the electrolysis of gold metal in KI with 0.1 M borate were analyzed by means of electrogravimetry for gold and spectrophotometry for . At low current density, the gold species formed during the electrolysis process was Au(I) in KI with 0.1 M borate. Voltammetric measurements for the solution resulting from electrochemical dissolution of gold in on a glassy carbon rotating disk electrode enable us to measure the diffusion coefficient of Au(I) in the same medium, which was found to be . The equilibrium of the chemical reaction between gold and iodine in the medium of was also studied. The experimental results confirmed that the complex formed between Au(I) and iodide is . The stability constant for was determined by direct analysis of equilibrated solutions and was found to be .
Action Learning and its Applications (2010)

This second volume of two discusses the employment of action learning in different contexts, including healthcare, education, government, military and the business world. Use of action learning in del
ChemInform Abstract: Triazolo(4,5‐d)pyrimidines. Part 12. Reactions of 6‐Benzoyl‐6,7‐ dihydro‐3‐phenyl‐3H‐1,2,3‐triazolo(4,5‐d)pyrimidines (I) ( Triazolopyrimidine Reissert Compounds) with Acid, Base, and Electrophile, e.g. (X). (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Factor H binding protein (fHbp)-mediated differential complement resistance of a serogroup C Neisseria meningitidis isolate from cerebrospinal fluid of a patient with invasive meningococcal disease (2021)

During an outbreak of invasive meningococcal disease (IMD) at the University of Southampton, UK, in 1997, two <i>Neisseria meningitidis</i> serogroup C isolates were retrieved from a student ('Case'), who died of IMD, and a close contact ('Carrier') who, after mouth-to-mouth resuscitation on the deceased, did not contract the disease. Genomic comparison of the isolates demonstrated extensive nucleotide sequence identity, with differences identified in eight genes. Here, comparative proteomics was used to measure differential protein expression between the isolates and investigate whether the differences contributed to the clinical outcomes. A total of six proteins were differentially expressed: four proteins (methylcitrate synthase, PrpC; hypothetical integral membrane protein, Imp; fructose-1,6-bisphosphate aldolase, Fba; aldehyde dehydrogenase A, AldA) were upregulated in the Case isolate, while one protein (Type IV pilus-associated protein, PilC2) was downregulated. Peptides for factor H binding protein (fHbp), a major virulence factor and antigenic protein, were only detected in the Case, with a single base deletion (ΔT366) in the Carrier fHbp causing lack of its expression. Expression of fHbp resulted in an increased resistance of the Case isolate to complement-mediated killing in serum. Complementation of fHbp expression in the Carrier increased its serum resistance by approximately 8-fold. Moreover, a higher serum bactericidal antibody titre was seen for the Case isolate when using sera from mice immunized with Bexsero (GlaxoSmithKline), a vaccine containing fHbp as an antigenic component. This study highlights the role of fHbp in the differential complement resistance of the Case and the Carrier isolates. Expression of fHbp in the Case resulted in its increased survival in serum, possibly leading to active proliferation of the bacteria in blood and death of the student through IMD. Moreover, enhanced killing of the Case isolate by sera raised against an fHbp-containing vaccine, Bexsero, underlines the role and importance of fHbp in infection and immunity.
Metamorphic protein IscU alternates conformations in the course of its role as the scaffold protein for iron–sulfur cluster biosynthesis and delivery (2013)

IscU from Escherichia coli, the scaffold protein for iron-sulfur cluster biosynthesis and delivery, populates a complex energy landscape. IscU exists as two slowly interconverting species: one (S) is largely structured with all four peptidyl-prolyl bonds trans; the other (D) is partly disordered but contains an ordered domain that stabilizes two cis peptidyl-prolyl peptide bonds. At pH 8.0, the S-state is maximally populated at 25 °C, but its population decreases at higher or lower temperatures or at lower pH. The D-state binds preferentially to the cysteine desulfurase (IscS), which generates and transfers sulfur to IscU cysteine residues to form persulfides. The S-state is stabilized by Fe-S cluster binding and interacts preferentially with the DnaJ-type co-chaperone (HscB), which targets the holo-IscU:HscB complex to the DnaK-type chaperone (HscA) in its ATP-bound from. HscA is involved in delivery of Fe-S clusters to acceptor proteins by a mechanism dependent on ATP hydrolysis. Upon conversion of ATP to ADP, HscA binds the D-state of IscU ensuring release of the cluster and HscB. These findings have led to a more complete model for cluster biosynthesis and delivery.
Hardware and Methods (2005)

This chapter contains sections titled: Hydrodynamic, Electrodynamic and Thermodynamic Transport in Porous Model Objects: Magnetic Resonance Mapping Experiments and Simulations Introduction Spin Density Diffusometry Flow Velocity and Acceleration Mapping Hydrodynamic Dispersion Thermal Convection and Conduction Mapping Ionic Current Density Mapping Concluding Remarks