gebhart/patrepeval huggingface dataset:
Recovering Intrinsic Images with a Global Sparsity Prior on Reflectance (2011)

We address the challenging task of decoupling material properties from lighting properties given a single image. In the last two decades virtually all works have concentrated on exploiting edge information to address this problem. We take a different route by introducing a new prior on reflectance, that models reflectance values as being drawn from a sparse set of basis colors. This results in a Random Field model with global, latent variables (basis colors) and pixel-accurate output reflectance values. We show that without edge information high-quality results can be achieved, that are on par with methods exploiting this source of information. Finally, we are able to improve on state-of-the-art results by integrating edge information into our model. We believe that our new approach is an excellent starting point for future developments in this field.
Enhanced vasoconstrictor sensitivity to exercise pressor reflex engagement in peripheral arterial disease (1156.7) (2014)

Exercise is associated with a rise in heart rate, blood pressure (BP) and blood flow to active muscle mediated by the exercise pressor reflex and regional release of vasodilators. In peripheral arterial disease (PAD) the exercise pressor reflex is enhanced. To assess the functional impact of the exercise pressor reflex, we determined BP and mean blood velocity (MBV, Doppler) in the popliteal artery and calculated vascular conductance (VC, MBV/mean BP) in the exercising and contralateral legs during graded rhythmic plantar flexion in 7 patients with PAD (age 67±2 yrs, ankle‐brachial‐index 0.6±0.1 in the ischemic leg) and in 5 controls. At peak exercise (2.0 kg, 1 Hz), the pressor effect was greatest in PAD when exercise was performed with the ischemic leg, and lowest in the controls. In controls, exercise did not affect VC in the contralateral inactive leg ( P =NS). Similarly, in PAD, exercise in the ischemic leg did not affect VC in the opposite inactive leg ( P =NS). In contrast, during exercise with the non‐ischemic leg, VC in the contralateral ischemic leg decreased by 24±10% ( P &lt;0.05). Thus, activation of the exercise pressor reflex resulted in vasoconstriction in the inactive but diseased leg. This suggests that despite upregulation of peripheral vasodilator factors, the vasculature of the ischemic leg is exquisitely sensitive to reflex vasoconstriction. Grant Funding Source : Supported by P01 HL096570 and UL1 TR000127
[P206]: A novel function for the Rb/E2F signaling pathway in regulating neuronal migration during cortical development (2006)

Retinoblastoma (Rb) family proteins are well known as key regulators of neural precursor proliferation, however, their role has been expanded as we have recently described a novel role for Rb in regulating neuronal migration during development. Using cortical slice co-culture assays we identified a cell autonomous requirement for Rb in regulating migration of ventrally derived interneurons in the developing telencephalon. In this study we sought to determine both the Rb interacting factors that mediate the proliferation and migration defects, and the downstream transcriptional targets that regulate neuronal migration. Members of the E2F transcription factor family are likely Rb interacting candidates. In particular, E2F1 and E2F3 are key regulatory targets that we and others have shown to be deregulated in the absence of Rb. We sought to determine the extent to which E2F1 and E2F3 are the interacting partners in Rb mediated neurogenesis using mice deficient for both Rb and E2F1 or E2F3 in the developing telencephalon. Here we report that compound absence of Rb and E2F3 appears to correct many of the proliferation, lamination, and migration defects observed in the Rb mutant. Using microarray based screening methods we have identified candidate E2F responsive genes that are known modulators of neuronal migration. These results so far suggest that Rb interacts through the E2F pathway to regulate neuronal migration during development. This work is supported by a CIHR operating grant to R.S.S. KLF and KAM, are supported by individual awards from CIHR. JLV is supported by an HSFC fellowship.
Ceramic BeO exoelectron dosimeters for tritium and radon monitoring (1979)

An environmental monitoring device with BeO ceramic dosimeters can be used to measure /sup 222/Rn in dwellings. Radon diffuses into a porous hemispheric chamber and the radon daughters are electrostatically collected on aluminized Mylar foil covering the BeO dosimeter that records the alpha activity. A 10:1 signal-to-background ratio results from a radon exposure of only pCi-h/l. This high sensitivity makes accurate radon measurement possible within one day, even at near background levels of a few tenths pCi/l. The BeO exoelectron dosimeter is also uniquely suited for monitoring occupational exposure to insoluble tritium gas. At one-fifth the maximum permissible concentration, exposure for 8 hours gives a 10:1 signal-to-background exoelectron response to the low energy beta rays. Compensation for any exoelectron response caused by photon radiation can be made by reading the thermoluminescence. The tritium exposure produces negligible thermoluminescence. Progress in these and other applications is now totally dependent on achieving reliability and long-term stability of the exoelectron dosimeter.
RF chirp extension via time division multiplexing (2006)

A novel method incorporating time division multiplexing technique with optical parabolic phase modulation has been introduced to overcome the limitations on optical generation of chirped RF signals. Extension of the frequency span and frequency sweep time of a RF chirp signal has been experimentally realized. A chirped RF signal with a center frequency of 100 MHz, frequency span of 20 MHz and sweep time of 200 ns has been generated via this novel method. This chirp signal agrees well with the chirp signal generated by conventional methods.
Supplementary Fig S4 from Targeting CD73 Enhances the Antitumor Activity of Anti-PD-1 and Anti-CTLA-4 mAbs (2023)

&lt;p&gt;Supplementary Fig S4 - PDF file 62K, Figure S4. Growth rates of carcinogen-induced tumors treated with anti-CD73/anti-PD-1 mAbs&lt;/p&gt;
Sub‐100‐nm STIM imaging and PIXE quantification of rare earth elements in algae cells (2013)

The uptake of rare earth elements (REEs) such as Nd 3+ , Gd 3+ , and Er 3+ by Euglena gracilis 848 algae cells has been studied using nuclear microprobe techniques at the Centre for Ion Beam Applications (CIBA), National University of Singapore. The cell imaging facility recently constructed at CIBA allows scanning transmission ion microscopy (STIM) down to the sub‐100‐nm level and provides energy loss images of whole intact cells. Helical coiling of the pellicle strips of the algae cells was observed, as was Rutherford backscattering spectrometry (RBS) images showing the distribution of erbium in the cell. Quantification of the REEs was carried out using a combination of nuclear techniques such as proton‐induced X‐ray emission, RBS, and STIM. Our results indicate significant variability in the uptake of REEs by algae cells. The amount of erbium absorbed was nearly one order of magnitude higher than that of neodymium, whereas the Gadolinium uptake was below the detection limit of 200 ppm. Copyright © 2013 John Wiley &amp; Sons, Ltd.
Oral and genital tardive pain syndromes (1994)

We report the development of chronic painful oral or genital sensations in 11 patients with tardive akathisia, tardive dyskinesias, or tardive dystonia. In each case, the pain syndrome became a source of profound distress for the patient, overshadowing all other concurrent neuropsychiatric symptoms, and requiring treatment. Agents effective in treating tardive dyskinesia and tardive akathisia, such as catecholamine depletors, proved effective in reducing the painful sensations. Our observations support the concept of tardive pain as a complication of chronic neuroleptic exposure.
Estimate of vascular permeability and cerebral blood volume using Gd‐DTPA contrast enhancement and dynamic T2*‐weighted MRI (2006)

Using a single imaging acquisition, the three most important vascular properties, CBV, cerebral blood flow (CBF), and permeability, can be estimated. This approach may have potential in clinical evaluation of patients with brain tumor or acute ischemic stroke.
The Exchange of Water between Co(NH3)5H2O+++ and Solvent (1952)

The rate of exchange of water between Co(NH3)5H2O+++ and solvent has been measured by a method involving isotopic assay of the bound water. The half-time for the exchange is independent of salt concentration and of acidity over a range of these variables and is 24.5 hr at 27°. The half-time is increased by SO4=, indicating that complex ion formation competes with the exchange process and thus supporting an SN1 mechanism as a reaction path. The equilibrium quotient [Co(NH3)5H2O18+++](H2O)/(Co(NH3)5H2O+++)×(H2O18) was measured as 1.019±0.001.
Viscoelastic Simulation of P.E.T Stretch/Blow Molding (1993)

International audience
Ensuring Privacy and Security in E- Health Records (2018)

Mobile medicine and health care have been adopted on a very large scale with support from the influx of medical devices and increased usability of remote health services. These are combined with an approachable interest of the patients and a readily approachable conscience about their healthcare. This leads to a huge set of medical data. These data sets require secure transfer, archival and access. In this study, we have proposed an efficient approach to preserve the identity and also protect the privacy of clinical data using highly effective encryption scheme. Moreover, we have also discussed an authorization framework using access of varying degrees. Medical records are often accessed by various entities with varying degrees of authorization. In this study, we have implemented the AT&T scheme for managing the access control mechanism of patients data. Further, encryption is undertaken using ARCANA, that provides hierarchically satisfied access to various data resources. It utilizes the XACML access model to formulate the access control framework. The primary reason for using this model is the regulation to access the data through AT&T based on XACML policies. In addition to this, the encrypting of medical data using various authorization techniques have been required for the proper data access regulation. Which may impact trust of the users in the e-health paradigm and in turn increase the large-scale usability.
Transmission System Planning for Integration of Renewable Electricity Generation Units (2020)

This paper summarizes the operational challenges imposed by integration of renewable electricity generation units in transmission level where the most common renewable generation units are solar and wind farms at the scale of 100s to 1000s MW. Such units, because of their stochastic nature, introduce new complexity and uncertainty to the grid. Throughout this paper, some results from the recent planning study of integration of 1,000 MW offshore wind farm into the U.S. Eastern Interconnection transmission system are shown.
Thermally stimulated current and dielectric relaxation of inorganic/organic ferroelectric nanocomposites (2008)

PA11/BaTiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> nanocomposites were elaborated with various particles size. These samples were poled under low field to elaborate poled ceramic/unpoled polymer composite. We found that the piezoelectric coefficient is highly poling temperature and poling time dependent. By poling the samples above the glass transition of the matrix, the piezoelectric coefficient of the composite were performed. The maximum piezoelectric coefficient measured was 5 pC/N for a PA 11/BaTiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> 700nm with phi = 0.4 poled under low field (3.3 kV/mm). It is higher than the piezoelectric coefficient of a stretched PA11 poled under high field (100 kV/mm).
An investigation into the role of dendrimers as potential enhancers of the dermal delivery of topically applied chlorhexidine (2013)

The reduction of bacteria on the skin results in prophylactic and therapeutic benefits by reducing the occurrence of skin infections. Currently, chlorhexidine digluconate, a conventional topical antiseptic, permeates the skin poorly leaving viable opportunistic pathogens below the superficial layers of the stratum corneum. The aim of this study was to use polyamidoamine (PAMAM) dendrimers to enhance the topical delivery of chlorhexidine digluconate to improve its antimicrobial efficacy.
SYNTHETIC LETHALITY AND SEMI-LETHALITY AMONG FUNCTIONALLY RELATED MUTANTS OF DROSOPHILA MELANOGASTER (1968)

sex-linked mutant deep orange (dor) of Drosophila melanogaster is Tzonsible for a peculiar type of female sterility: mutant females produce no progeny when crossed to mutant males but yield some offspring (heterozygous daughters) when mated to wild-type males (MERRELL 1947). The effects of this mutant on embryonic development have been extensively studied by COUNCE (1956a) and more recently by HILDRETH and LUCCHESI (1967). In addition to the sterility phene, dor alters the pigmentation of the eyes (which are orange in color) and confers an abnormal spectrum of relative pteridine concentrations. An unusual characteristic of dor is that isoxanthopterin appears to be accumulated by mutant females (COUNCE 1957). During the course of preliminary investigations into the biochemical basis of dor female-sterility, art attempt was made to prevent the accumulation of isoxanthopterin in mutant females by genetic means. This resulted in the discovery of a highly specific synthetic lethal system involving dor and a non-allelic third chromosome mutant, rosy (ry) . The dor-ry system is similar to three other synthetic lethal systems, previously described in D. melanogaster: purpleoid (pd) and Purpleoider (Pdr) (BRIDGES 1922; as cited in BRIDGES and BREHME 1944) ; prune (pn) and Prune-killer (K-pn) ( STURTEVANT 1956) ; and Henna-recessiue-3 (Hnr3) and rosy (ry6) (TAIRA 1960; GOLDBERG, SCHALET and CHOVNICK 1962). A search was undertaken for the purpose of uncovering additional interactions among some of the mutants mentioned above. Since six of the latter affect eye color and/or pteridine levels, a number of other eye color mutants were tested. In addition, the female sterile mutant fused (fu) , similar in many respects to dor (although allowing lethal embryos to develop further than dor embryos (COUNCE 195613) ). was used in <some crosses. The results of these investigations are presented in this paper.
Leptin-dependent platelet aggregation and arterial thrombosis suggests a mechanism for atherothrombotic disease in obesity (2001)

Obesity is associated with increased cardiovascular morbidity and mortality and with elevated circulating levels of the satiety factor leptin. This study provides evidence for a direct link between leptin and the risk for thrombotic complications in obese individuals. For example, although arterial injury provokes thrombosis in both lean and obese (ob/ob) mice, the time to complete thrombotic occlusion is significantly delayed in the ob/ob mice, and the thrombi formed are unstable and frequently embolize. The ob/ob mice lack leptin, and intraperitoneal administration of leptin to these mice before injury restores the phenotype of lean mice by shortening the time to occlusion, stabilizing the thrombi, and decreasing the patency rate. The thrombi that form when leptin receptor-deficient obese (db/db) mice are injured also are unstable. However, in this instance, leptin has no effect. Platelets express the leptin receptor, and leptin potentiates the aggregation of platelets from ob/ob but not db/db mice in response to known agonists. These results reveal a novel receptor-dependent effect of leptin on platelet function and hemostasis and provide new insights into the molecular basis of cardiovascular complications in obese individuals. The results suggest that these prothrombotic properties should be considered when developing therapeutic strategies based on leptin.
Substrate and back contact effects in CIGS devices on steel foil (2003)

In comparison to CIGS-based photovoltaic devices deposited onto soda-lime glass substrates, the observed efficiency limitations of similar devices prepared on flexible metal substrates have been attributed to factors that include: (a) lack of sodium out-diffusion from the substrate; (b) impurity out-diffusion from the substrate, and (c) substrate roughness. While intentional Na incorporation via deposition of a Na-containing precursor has previously been studied extensively in the literature, this investigation focuses on the latter two issues. If thin metal back contact layers are employed, these two factors are more closely linked than for thick back contact layers. The effects of various metal surface-finishing techniques on substrate roughness, impurity out-diffusion, and subsequent device performance are examined.
Advances in Metal and Semiconductor Clusters:  Cluster Materials. Volume 4 Edited by M. A. Duncan. JAI Press:  New York. 1998. 402 pp. $109.50. ISBN 0-7623-0058-2. (1999)

ADVERTISEMENT RETURN TO ISSUEPREVBook ReviewAdvances in Metal and Semiconductor Clusters: Cluster Materials. Volume 4 Edited by M. A. Duncan. JAI Press: New York. 1998. 402 pp. $109.50. ISBN 0-7623-0058-2.C. M. LukehartView Author Information Vanderbilt UniversityCite this: J. Am. Chem. Soc. 1999, 121, 33, 7728Publication Date (Web):July 16, 1999Publication History Published online16 July 1999Published inissue 1 August 1999https://pubs.acs.org/doi/10.1021/ja9857155https://doi.org/10.1021/ja9857155book-reviewACS PublicationsCopyright © 1999 American Chemical SocietyRequest reuse permissionsArticle Views130Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Cluster chemistry,Materials,Metal clusters,Metals,Nanoparticles Get e-Alerts
Closed-loop feedback control of microfluidic cell manipulation via deep-learning integrated sensor networks (2021)

An adaptive microfluidic system changing its operational state in real-time based on cell measurements through an on-chip electrical sensor network.
Alexandria: A Proof-of-Concept Implementation and Evaluation of Generalised Data Deduplication (2019)

The amount of data generated worldwide is expected to grow from 33 to 175 ZB by 2025 in part driven by the growth of Internet of Things (IoT) and cyber-physical systems (CPS). To cope with this enormous amount of data, new cloud storage techniques must be developed. Generalised Data Deduplication (GDD) is a new paradigm for reducing the cost of storage by systematically identifying near identical data chunks, storing their common component once, and a compact representation of the deviation to the original chunk for each chunk. This paper presents a system architecture for GDD and a proof-of-concept implementation. We evaluated the compression gain of Generalised Data Deduplication using three data sets of varying size and content and compared to the performance of the EXT4 and ZFS file systems, where the latter employs classic deduplication. We show that Generalised Data Deduplication provide up to 16.75% compression gain compared to both EXT4 and ZFS with data sets with less than 5 GB of data.
Supplementary Figure 6 from Combining a PI3K Inhibitor with a PARP Inhibitor Provides an Effective Therapy for BRCA1-Related Breast Cancer (2023)

&lt;p&gt;PDF file - 159K, Erk phosphorylation after treatments with NVP-BKM120 in vivo. Tumor tissues were harvested from MMTV-CreBRCA1f/fp53+/- mice within 3 hours after the last treatment with NVP-BKM120. Tissues were fixed and processed for immunohistochemistry with anti-phospho ERK (Thr202/Tyr204) antibodies. 400 x magnification&lt;/p&gt;
Phosphorus-31 NMR visibility and characterization of rat liver mitochondrial matrix adenine nucleotides (1989)

Compartmentation and NMR visibility of mitochondrial adenine nucleotides were quantitated in isolated rat liver mitochondria respiring on succinate and glutamate in vitro at 8 and 25 degrees C. Intra- and extramitochondrial nucleotides were discriminated by adding the chelator trans-1,2-diaminocyclohexane-N,N,N',N'-tetraacetic acid (CDTA). T1 values of about 0.2-0.3 s for magnesium-bound matrix nucleotides were determined. Adenine nucleotide T1 values were influenced by the ionic environment; only magnesium-free ATP T1's were affected by temperature. Intra- and extramitochondrial adenine nucleotide ratios were varied in ATP-loaded mitochondria with added ATP and phosphate using the mitochondrial inhibitors oligomycin and carboxyatractyloside, and adenine nucleotides were quantitated by using NMR and enzymatic analysis. There was good agreement between matrix ATP concentrations (magnesium-bound ATP) calculated by using NMR and standard biochemical techniques. Although matrix ADP could be detected by NMR, it was difficult to quantitate accurately by NMR. The data indicate that mitochondrial ATP is NMR-visible in isolated mitochondria in vitro.
Two New Secoiridoid Glycosides fromGentiana algida (1997)

Two new acylated secoiridoid glycosides were isolated from the aqueous acetone extract of the whole herb of Gentiana algida. The structures of these new products were established by spectral and chemical methods as 6'-(2,3-dihydroxybenzoyl)sweroside and 6'-(2,3-dihydroxybenzoyl)swertiamarin, respectively.