gebhart/patrepeval huggingface dataset:
Sensation: a middleware integration platform for pervasive applications in wireless sensor networks (2005)

In this paper we focus on the issue of application development for wireless sensor networks (WSN). Currently, such networks are extensively used in various business domains. However, their highly customized operating systems and application middleware render the application development for multiple WSNs rather cumbersome. Applications based on multiple WSNs are typical in the emerging pervasive computing paradigm adopted in numerous domains (e.g., telemedicine). A WSN can be considered as a source of information similarly to a database. Motivated by the layered driver approach introduced in the ODBC/JDBC frameworks, we propose a middleware integration architecture. Our architecture presents a unified and developer-friendly interface and abstract data model towards the application. Such interface conceals the peculiarities of the underlying WSNs as their coordination and data retrieval software is integrated in the lower layer of the proposed middleware framework. We present the design of the discussed architecture that is based on open standards like XML.
The case for enterprise-ready virtual private clouds (2009)

Cloud computing platforms such as Amazon EC2 provide customers with flexible, on demand resources at low cost. However, while existing offerings are useful for providing basic computation and storage resources, they fail to provide the security and network controls that many customers would like. In this work we argue that cloud computing has a great potential to change how enterprises run and manage their IT systems, but that to achieve this, more comprehensive control over network resources and security need to be provided for users. Towards this goal, we propose CloudNet, a cloud platform architecture which utilizes virtual private networks to securely and seamlessly link cloud and enterprise sites.
NAG‐1/GDF15 inhibits HFD‐induced obesity and inflammation by modulating gut microbiota (2019)

Nonsteroidal anti‐inflammatory drug‐activated gene (NAG‐1) or growth differentiation factor 15 (GDF15) is a divergent member of the transforming growth factor beta (TGF‐β) superfamily. Mice expressing NAG‐1/GDF15 have been shown to be resistant to high fat diet (HFD)‐induced obesity and inflammation. However, the exact mechanism underlying the anti‐obesity effects of NAG‐1/GDF15 remains unknown. The objective of this study was to examine whether the anti‐obesity effects of NAG‐1/GDF15 is associated with gut microbiota modulation and gut barrier function regulation. First, we confirmed that NAG‐1/GDF15 Tg mice are resistant to dietary induced obesity and inflammation. These mice also demonstrated improved insulin sensitivity compared to Wt littermates. We then found these phenotypic differences were correlated with differences in the composition of gut microbiota, gut barrier function and short chain fatty acids compositions in feces as determined by standard molecular biological methods. In addition, HFD reduced the expression of Cyp7a1 , Cyp7b1 , Cyp27a1 , Ntcp , Mdr2 , and Oatp that regulate bile acid metabolism in liver. However, the expression of these genes were increased in NAG‐1/GDF15 Tg mice. Furthermore, antibacterial peptide (Reg3g, Lyz‐1 and Defa) and MUC2 in small intestine were up‐regulated in NAG‐1/GDF15 Tg mice. We also found that NGA‐1/GDF15 down‐regulate the expression of TLR4 and its downstream signals in fat, liver and small intestines at both mRNA and protein levels as determined by Western blot and qRT‐PCR. Finally, we transplanted feces from NAG‐1/GDF15 mice into pseudo germ‐free mice and fed the mice with HFD and found that a shift in gut microbiota composition from NAG‐1/GDF15 mice could inhibit the development of obesity and inflammation. Taken together, our results indicate that the protection role of NAG‐1/GDF15 against HFD‐induced obesity and inflammation is mediated, at least in part, by the modulation of gut microbiota, function of gut barrier, and bile acid metabolism. Support or Funding Information National Natural Science Foundation of China Grant No. 81400822. This abstract is from the Experimental Biology 2019 Meeting. There is no full text article associated with this abstract published in The FASEB Journal .
Insights into interfacial activation from an open structure of Candida rugosa lipase (1993)

The structure of the Candida rugosa lipase determined at 2.06-A resolution reveals a conformation with a solvent-accessible active site. Comparison with the crystal structure of the homologous lipase from Geotrichum candidum, in which the active site is covered by surface loops and is inaccessible from the solvent, shows that the largest structural differences occur in the vicinity of the active site. Three loops in this region differ significantly in conformation, and the interfacial activation of these lipases is likely to be associated with conformational rearrangements of these loops. The "open" structure provides a new image of the substrate binding region and active site access, which is different from that inferred from the structure of the "closed" form of the G. candidum lipase.
Short wavelength (5.36–1.85 μm) nonlinear spectroscopy of coupled InGaAs/AlAs intersubband quantum wells (1994)

We report short wavelength second-harmonic generation (SHG) spectroscopy of asymmetric coupled In0.6Ga0.4As/AlAs quantum wells (QWs). The QW is designed to show maximum second-order nonlinear susceptibility χ(2) for SHG of 4 and 2 μm wavelengths by single and double resonance effects, respectively. SHG spectroscopy across the midinfrared is measured using both a CO2 and a free electron laser as pumps. The χ(2) of the QW is extracted from interference of the second-harmonic fields from the QW and GaAs substrate, determined by the azimuthal dependence of the SHG power. We measure χ(2) of the QW for harmonic wavelengths between 5.36 and 1.85 μm. This is the shortest wavelength SHG to date by any QW intersubband interaction. Good agreement of experiment with theory for the dispersion of χ(2) for both singly and doubly resonant conversion is observed throughout the midinfrared.
Ultrastructure of airways in children with asthma (1978)

This study describes the histopathology and ultrastructure of bronchial mucosa in lung biopsies from two children with bronchial asthma in remission, and compares them with lung samples from two children who died in status asthmaticus. Light microscopy of all samples showed changes typical of bronchial asthma, e.g. mucus plugging, goblet cell hyperplasia, 'thickening of bronchial basement membrane', peribronchial smooth muscle hypertrophy and eosinophilic infiltration. Electron microscopy revealed that the mucus plugs consisted of moderately electron-dense floccular material containing degenerate epithelial cells, macrophages and cell fragments. The luminal surfaces of ciliated cells showed cytoplasmic blebs and abnormal cilia. Mast cells in various stages of degranulation were scattered between bronchial epithelial cells. The subepithelial hyaline layer, commonly referred to as "thickened basement membrane", consisted of collagen fibrils in plexiform arrangement. The basement membrane proper appeared intact. These electron microscopic changes, particularly the presence of mast cells and subepithelial collagen deposits, were also found in autopsy samples. This combined light and electron microscopic study shows that marked, possibly irreversible changes may be present in the lungs of patients with severe bronchial asthma, even when they are asymptomatic. These pulmonary changes could be the direct consequence of mast cell activation and the release of various mediators. No evidence of immune complex deposition was found.
Studies on the Enzymatic Degradation of Plant Tissue Part II (1969)

(1) 馬鈴薯を用いてAsp.sojaeNO.48のmacerating activityを測定したところ,optimum pHは5.5付近に認められた. (2) 本酵素中には,pectic acid saccharifying activity, liquefying activityおよびpectin liquefying acitivityの活性が認められ,optimum pHはそれぞれ4.0,4.5および5.5であったが,pectin esteraseの活性は全く認められなかった. (3) Pectinに特異的なlyaseの存在が認められた. (4) Macerationにはpectin liquefying activityの関与が推定された. (5) Yeast glucan, pachyman, laminarin, lutean等を分解するβ-glucanase活性が認められた. (6) その他chitinase, protease, amylaseも存在することが認められた.
ChemInform Abstract: Lariat Ethers with a Novel Proton‐Ionizable Group. Synthesis and Solvent Extraction of Alkali Metal Cations. (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Electroless Copper Plating of Inkjet-Printed Polydopamine Nanoparticles: a Facile Method to Fabricate Highly Conductive Patterns at Near Room Temperature (2014)

Aqueous dispersions of artificially synthesized, mussel-inspired poly(dopamine) nanoparticles were inkjet printed on flexible polyethylene terephthalate (PET) substrates. Narrow line patterns (4 μm in width) of poly(dopamine) resulted due to evaporatively driven transport (coffee ring effect). The printed patterns were metallized via a site-selective Cu electroless plating process at a controlled temperature (30 °C) for varied bath times. The lowest electrical resistivity value of the plated Cu lines was about 6 times greater than the bulk resistivity of Cu. This process presents an industrially viable way to fabricate Cu conductive fine patterns for flexible electronics at low temperature, low cost, and without need of sophisticated equipment.
Supplementary Figure S3 from Mixed Response to Cancer Immunotherapy is Driven by Intratumor Heterogeneity and Differential Interlesion Immune Infiltration (2023)

&lt;p&gt;Peptide assay.&lt;/p&gt;
Development of Image Guided MRI Compatible Manipulator with Electromagnetic Wave Measurement (2008)

Surgical mechatronics systems in a MRI environment promise a popular strategy for minimize invasive treatment. We developed an image guided MRI compatible manipulator with ultrasound motors used inside the MRI gantry. MRI compatibility is important in the development of a manipulator, since the effects of magnetic materials and the influence of electromagnetic wave leakage on MRI images should be considered. We evaluated the effect of electromagnetic waves on MR images and clarified the RF immunity level of the image. We also describe an electromagnetic wave shield required for MRI compatibility. We measured the leakage of electromagnetic waves as a novel way of evaluating MRI compatibility based on the results of our findings of RF immunity on images. We also quantified the MR compatibility of the manipulator based on MR images and electromagnetic wave measurements. The decrease in the signal-to-noise ratio (SNR) and distortion, caused by the manipulator inside a 0.2 T MRI gantry, and electromagnetic wave leakage to the actuator were evaluated. The results showed that MR images were only distorted for less than 2 pixels, and that the SNR decreased by 0.6%. Electromagnetic wave leakage at a resonance frequency band of 0.2 T MRI was undetectable. Therefore, the manipulator has high MRI compatibility and could be driven while acquiring MR images. This evaluation method is effective for developing novel MRI compatible mechatronics systems for use during the acquisition of MR images.
Neural algorithms and computing beyond Moore's law (2019)

Advances in neurotechnologies are reigniting opportunities to bring neural computation insights into broader computing applications.
Peptide Amyloid Surface Display (2014)

Homomeric self-assembly of peptides into amyloid fibers is a feature of many diseases. A central role has been suggested for the lateral fiber surface affecting gains of toxic function. To investigate this, a protein scaffold that presents a discrete, parallel β-sheet surface for amyloid subdomains up to eight residues in length has been designed. Scaffolds that present the fiber surface of islet amyloid polypeptide (IAPP) were prepared. The designs show sequence-specific surface effects apparent in that they gain the capacity to attenuate rates of IAPP self-assembly in solution and affect IAPP-induced toxicity in insulin-secreting cells.
Biotinylated Polypyrrole Modified Quartz Crystal Microbalance for the Fast and Reagentless Determination of Avidin Concentration (2001)

A quartz crystal microbalance (QCM) bioaffinity sensor for avidin, based on electropolymerized biotinylated polypyrrole film, was developed. The functionalization of one of the Au quartz electrode has been achieved by controlled potential oxidation of a biotinyl pyrrole monomer in CH3CN. The modified quartz resonator was placed in a QCM flow cell. In the presence of avidin solutions, gravimetric measurements indicated the reproducible formation of a compact avidin layer via the specific avidin-polymerized biotin interaction. The polymerized biotin retained identical bioaffinity properties for avidin over a period of one month. The initial slope of the frequency change as a function of time was recorded and related to avidin concentrations. Avidin concentration in the range 1.5×10−9–3.7×10−5 M can be measured by this method.
The Competence-Oriented Teaching of Antennas, Propagation, and Wireless Communications: Enabling independent students (2020)

Competence-oriented education aims to teach individuals the cognitive skills required to solve specific problems and the readiness needed to apply such solutions in versatile situations. We find that competence-oriented teaching is a promising paradigm in applied courses for antennas, propagation, and wireless communications. Competenceoriented laboratory courses are easy to implement when the mechanical facilities and equipment from laboratory courses are already available at the institute. Amateur radio equipment is used so that students can work independently without risking damage to delicate equipment. In this article, we describe several methods used to modify lab courses toward competence-oriented academic teaching that we have found are popular with students and enhance their learning experience.
Corrections of magnification and focusing in a cathode lens-equipped scanning electron microscope (2006)

One of the well-proven and efficient methods of obtaining a very low-energy impact of primary electrons in the scanning electron microscope is to introduce a retarding field element below the pole piece of the objective lens (OL). It is advantageous to use the specimen alone as the negatively biased electrode (i.e., cathode of the cathode lens). The optical power of the cathode lens modifies some of the standard parameters of the image formation such as relation of working distance to OL excitation or magnification to the scanning coils current, the impact angle of primary electrons, and so forth. In computer-controlled electron microscopes these parameters, particularly with regard to focusing and magnification, can be corrected automatically. Derivation of algorithms for such corrections and their experimental verifications are presented in this paper. Furthermore, a more accurate analytical expression for the focal length of an aperture lens is derived.
Homogeneous synthesis of cellulose p‐toluenesulfonates in N,N‐dimethylacetamide/LiCl solvent system (1996)

Abstract Pure cellulose p‐toluenesulfonates (tosylates) with an insignificant formation of chlorodeoxy groups were prepared by reacting cellulose dissolved in a solution of N,N‐dimethylacetamide and LiCI with tosylchloride (Tos‐CI) in the presence of triethylamine within 24 h at 8°C. Various cellulosic starting materials with a degree of polymerization from 280 to 5 100 were used. The samples obtained were characterized by means of elemental analysis, FTIR and 13 C NMR spectroscopy, and their intrinsic viscosities. The rise of the molar ratio of Tos‐CI/anhydroglucose unit (AGU) from 0.6 to 9.0 leads to an increase in the degree of substitution (DS) from 0.4 up to a maximum value of 2.3. The cellulose tosylates are readily soluble in common organic solvents like dimethyl sulfoxide (within the whole DS range) and in N,N‐dimethylacetamide, N,N‐dimethylformamide, acetone, tetrahydrofuran and trichloromethane depending on DS. As revealed by 13 C NMR spectroscopy a faster tosylation takes place at the O‐6 atom of AGU compared with the O‐2/3 atoms. This was additionally confirmed by analysis of the corresponding iododeoxy celluloses synthesized with NaI in acetylacetone. Furthermore, some important properties as stability against alkaline and heat were studied as well.
Dynamic contrast‐enhanced MRI in advanced nonsmall‐cell lung cancer patients treated with first‐line bevacizumab, gemcitabine, and cisplatin (2012)

DCE MRI enables a functional analysis of the treatment response of NSCLC. MRI parametric histogram has the potential to predict early treatment response of combined bevacizumab, gemcitabine, and cisplatin.
A decentralized architecture for consolidating personal information ecosystems: The WebBox (2012)

Most existing PIM tools either suffer from having data iso-lated by being siloed in an application or only interact with specific tools offered through specific services. The conse-quences are that what people can do with their own data becomes constrained by what services application develop-ers afford. We propose a web-standards based architecture called WebBox to support easy maintenance and repurpos-ing of one’s own data for private, social or public publishing, collaboration and reuse.
Laboratory Methods for Determining Moisture Absorption of Thermal Insulactions (1983)

In a review of laboratory tests of moisture absorption, three methods are carefully examined and compared. Comparisons of laboratory and field data, generally conceded to be the best way to evaluate laboratory test methods, led to the conclusion that moisture gain in perimeter insulation cannot be predicted accurately by any one laboratory test, but that relative assessment is possible from the results of a combination of tests. This paper reviews the state of the art, in particular the work of the ASTM task group on moisture absorp tion.
Wintry jewel of the Highveld : the parasitic plant, Harveya pumila , flowers briefly in late winter before the first spring rains - a fairly common strategy amongst many wildflowers of the Highveld grasslands : feature (2005)

A common misconception is that winter on the Highveld can be equated to the classic poem 'Winternag' by Eugene N. Marais. True enough, this poetic account describes our clear, icy, Highveld winter nights very accurately, but the haunting, forlorn feeling one is left with at the end quickly disappears once the sun comes out. Frost slowly starts to melt, revealing a glistening wonderland full of botanical jewels for anybody to find.
Systematic assessment of inflammation by magnetic resonance imaging in the posterior elements of the spine in ankylosing spondylitis (2009)

Inflammatory lesions in the posterior elements were present in the majority of patients with AS, and standard MRI protocols of the spine should be modified to ensure adequate visualization of posterolateral structures.
Dementia Still Diagnosed Too Late - Data from the Czech Republic. (2014)

The sensitivity of Czech physicians to the early diagnosis of dementia is very low. Any delay in starting the treatment of dementia means a worsened effectiveness of this treatment, a worsened quality of life of patients with dementia and their caregivers. Our recommendations for both the early diagnosis and treatment of dementia should be involved in guidelines and should become a part of the pregraduate and postgraduate education of all physicians.
Web-scale k-means clustering (2010)

We present two modifications to the popular k-means clustering algorithm to address the extreme requirements for latency, scalability, and sparsity encountered in user-facing web applications. First, we propose the use of mini-batch optimization for k-means clustering. This reduces computation cost by orders of magnitude compared to the classic batch algorithm while yielding significantly better solutions than online stochastic gradient descent. Second, we achieve sparsity with projected gradient descent, and give a fast ε-accurate projection onto the L1-ball. Source code is freely available: http://code.google.com/p/sofia-ml
ADHD Is Comorbid to Migraine in Childhood: A Population-Based Study (2017)

<b>Objective:</b> Recurrent headaches and ADHD are prevalent in the pediatric population. Herein, we assess if ADHD is comorbid to headaches overall, to headache subtypes (e.g., migraine), and to headache frequency. <b>Method:</b> Informed consent and analyzable data were obtained for 5,671 children aged 5 to 12 years (65.9% of the target sample). Parents and teachers were interviewed using validated questionnaires based on the <i>Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5)</i>. Relative risks were modeled using univariate and multivariate analyses. <b>Results:</b> As contrasted to nonheadache controls, the prevalence of ADHD was significantly higher in children with migraine (<i>p</i> < .001) but not in those with tension-type headaches. In children with migraine, risk of ADHD increased as a function of headache frequency (<i>p</i> < .05). <b>Conclusion:</b> Migraine and frequent migraine are comorbid to ADHD. Future studies should focus on the impact of the association on the burden to the children and their families.
Replication package for "TacTok: Semantics-aware proof synthesis" (2020)

A VirtualBox VM with the results (and scripts to process the results) found in the OOPSLA 2020 paper "TacTok: Semantics-Aware Proof Synthesis". The VM also has the code for running the TacTok tool with pre-trained models. Attached is a compressed file with the training examples, `processed.tar.gz`. Note that the VM does not support training models. This image has been tested with VirtualBox Version 6.1.12. It requires 3GB RAM. The actual size of the vdi is 24.26GB, and is configured to dynamically allocate storage up to 70GB. The username is `oopsla` and the password is `oopsla`. For processing the results, follow the directions in `/home/oopsla/Documents/evaluation/results_commands.md`. For running TacTok, follow the directions in `/home/oopsla/Documents/run_tactok_commands.md`. Source code can be found at https://github.com/LASER-UMASS/TacTok
Symptomatic Hypoglycemia Associated with Trimethoprim/Sulfamethoxazole and Repaglinide in a Diabetic Patient (2010)

This interaction between TMP/SMX and repaglinide may have involved inhibition of CYP2C8 by trimethoprim. Clinicians should be aware that this association may lead to symptomatic hypoglycemia, particularly in patients with renal dysfunction.
Improving Median Housing Price Indexes through Stratification (2008)

There is a trade-off between how easy a housing price series is to construct and the extent to which it adjusts for changes in the mix of dwellings sold. Median house price measures are easily calculated, frequently used by industry bodies, and quoted in the media. However, such measures provide poor estimates of short-term changes in prices because they reflect changes in the composition of transactions, as well as changes in demand and supply conditions. This study uses a database of 3.5 million transactions in the six largest Australian cities to demonstrate that compositional shifts between higher- and lower-priced parts of cities can account for much of the noise in median price measures. Accordingly, a simple method of adjusting for compositional change through stratification is proposed. The measure differs from those commonly used internationally, as neighborhoods or small geographic regions are grouped according to the long-term average price level of dwellings in those regions. The measure of price growth produced improves substantially upon a median and is very highly correlated with regression-based measures.