gebhart/patrepeval huggingface dataset:
Taxotere Chemosensitivity Evaluation in Rat Breast Tumor by Multimodal Imaging: Quantitative Measurement by Fusion of MRI, PET Imaging with MALDI and Histology (2011)

Integration of imaging data with immunohistology is a new art. Increased PET and MRI image intensities on rat breast tumor MRI-PET images were reviewed for possible correlation with tumor histology and MALDI imaging tumor characteristics in the light of recent inventions and patents. Increased signal intensities of intracellular (IC) sodium μMRI and flouro-2-deoxy-glucose utilization by μPET from apoptosis protein rich MALDI visible regions of tumors were positively correlated to chemosensitivity of Taxotere. MCF-7 cancer cell line induced rat tumor MRI-PET images and histology digital images were compared for correlation in pre- and post taxotere treated tumors. For MALDI imaging, iterated protein ion mass spectrometry peak analysis was done using data from laser raster over tumor slices in sequence and 3D tumor volume was simulated for specific peak(s) distribution. A criterion was developed to evaluate malignancy by histology and MRI-PET imaging. For correlation, regression analysis was done using MRI-PET imaging, histology and MALDI imaging data from MCF-7 tumor after 24 hours post-taxotere treatment. Apoptosis indices were calculated by histostaining using pentachrome, feulgen and ss-DNA antibody assay. Review showed sodium MRI and PET signal intensity distribution comparable and measurable in tumor tissue regions. In tumors, taxotere induced an increase in IC-Na MRI signal with decreased tumor size and micro-PET showed FDG uptake increase with decreased tumor size than that of control tumors after 24 hours. Histology features indicated tumor risk (high ‘IC/EC ratio’, high mitotic index and apoptotic index), decreased tumor viability (reduced mitotic figures, reduced diploidy or aneuploidy and proliferation index) after Taxotere treatment. These features in co-registered IC-Na, μPET hypermetabolic and monoclonal antibody (ss-DNA) sensitive regions showed 6% difference. MALDI imaging showed tumor specific protein ion species and their distribution showed empirical correlation (limited visual match) with MRI-PET signal intensities but comparable match with histology features. Recent patents strongly suggest the possibility of sodium MRI and PET multimodal imaging integrated with MALDI-imaging as an non-invasive chemosensitivity assay to monitor the anticancer effect.
Infinite Hidden Markov Models for Unusual-Event Detection in Video (2008)

We address the problem of unusual-event detection in a video sequence. Invariant subspace analysis (ISA) is used to extract features from the video, and the time-evolving properties of these features are modeled via an infinite hidden Markov model (iHMM), which is trained using "normal"/"typical" video. The iHMM retains a full posterior density function on all model parameters, including the number of underlying HMM states. Anomalies (unusual events) are detected subsequently if a low likelihood is observed when associated sequential features are submitted to the trained iHMM. A hierarchical Dirichlet process framework is employed in the formulation of the iHMM. The evaluation of posterior distributions for the iHMM is achieved in two ways: via Markov chain Monte Carlo and using a variational Bayes formulation. Comparisons are made to modeling based on conventional maximum-likelihood-based HMMs, as well as to Dirichlet-process-based Gaussian-mixture models.
Enhancing Senior Capstone Design Course through International and Multidisciplinary Projects (2020)

Abstract Enhancing Senior Capstone Design Course through International and Multidisciplinary ProjectsAbstractOver the years the Mechanical Engineering capstone senior design course at our school hasevolved to parallel the real world engineering design projects found in the industry. This courseis designed to better prepare our senior mechanical engineering students for realistic hands-on,team based projects. We have methodically increased our interaction with industry to solicitexternally-sponsored projects such that about 80% projects are sponsored by corporations orgovernment research labs. Moreover, with the recent globalizing trend, engineering projects areincreasingly becoming multidisciplinary while involving international partners, making itimportant that we introduce more international projects to better prepare our students. In recentyears we increased our multidisciplinary projects significantly, closer to 50% of our total numberof projects have been multidisciplinary involving industrial, electrical/computer engineering andentrepreneurship program from the Business School. This year we have introduced threeinternational projects, two with two different Brazilian universities and one with a university inArmenia. More than 10% of our students are directly involved with these international projectsincluding 8 Brazilian students (3 during the fall-spring semesters and 5 more in spring 2012)actually work alongside with our students through an international exchange program. Inaddition, another 4 of our own students are currently working on the same projects in Brazilthrough the same exchange program.An international project introduces the students to a new set of challenges and demands that theyhave to pay special attention in order to function as an integrated and cohesive team. With ageographically separated team, we have found it requires more careful planning for projectcoordination and effective communication, which will help overcome language barriers, culturaldifferences as well as other obstacles that occur. Becoming skilled at effective communicationwith each other and with the industrial partners is important, so that the students gain anunderstanding of how to successfully manage those projects. Scheduling for the studentsbecomes difficult when there are several time zones between them. They are required to holdboth formal and informal team meetings, by videoconference and web meetings via social media,in order to communicate and function as a cohesive team. How the work load is distributed andmanaged between the team members is another key component to address when working on aninternational capstone design project.This paper will discuss the challenges, changes and accommodations we incorporated as part ofthis course for executing those multidisciplinary/international projects where students are fromdifferent departments and countries. It will outline how these challenges are addressed in thecapstone design courses between departments and international partners.
Gravity Platform Tower Vibration (1977)

ABSTRACT The paper presents results of vibration tests on two concrete gravity structures, comprising free tower vibration in air and in submerged position and from a platform installed in the North Sea. Dynamic properties of tested structures are compared with design assumptions, and their influence on extreme loads and fatigue life is discussed. The observations indicate a conservative design. INTRODUCTION The design of offshore gravity platforms necessitates a dynamic response analysis to account for dynamic load effects on the structure. Several gravity type structures are now in service, both in the North Sea and elsewhere. The purpose of this paper is to describe tests which have been carried out to determine platform dynamic characteristics and to discuss how these compare with some of the design analysis assumptions. A typical platform, designed for a water depth of 145 m, is the Mobil Statfjord A platform. It is fitted with a large caisson which provides buoyancy for deck and process equipment during tow-out, later on the caisson serves as oil storage tank. Drilling takes place through two of three towers which support the deck. The third tower serves as utility providing space for pumps, generators etc. concerned with ballasting and loading operations. The Substructure, comprising caisson and towers, is slip-formed in concrete, whilst the deck is made out of steel in order to reduce the top load during tow-out. Fig. 1 shows the complete platform with a height of more than 200 m. The caisson base is fitted with steel and concrete skirts to transfer horizontal loads at mudline. Grouting will take place to ensure that vertical loads are evenly distributed underneath the platform. The environmental loads acting on the platform are dynamic, and this affects the design analysis w.r.t:Extreme loads (waves, wind, earthquakes).A fatigue analysis for the anticipated platform life.Local vibration levels (i.e. at top deck) to satisfy facilities and equipment design. The behaviour of offshore platforms under dynamic loading conditions has received much attention in recent years, and the state of the art has been significantly advanced by contributions from Penzien and others (1), (2), (3). These are primarily concerned with spectral techniques, whereas an actual design load may be specified in deterministic terms (i.e. a design wave) as well as stochastic (4). The analysis of dynamic structural response requires that some model is formulated, both to represent the soil/ water/structure interaction system and to represent the forcing functions. Also, the complexity of the interaction problems makes it necessary to effect a compromise between the mathematical model accuracy and its size. Most investigations assume a linear system so that solutions can be based upon normal mode superposition. The principal advantage of this method is that fairly complex systems can be analysed over a wide frequency range without running up large computer costs, and parametric response studies are thus permitted. Such studies are valuable to single out response sensitivities and allow more efficient use of detailed analysis.
Ozone Dissociation to Oxygen Affected by Criegee Intermediate (2014)

The detailed potential energy surfaces for the reactions of Criegee intermediate (CI, H2COO) and formaldehyde (H2CO) with ozone (O3) have been investigated at the CCSD(T)/aug-cc-pVDZ//B3LYP/6-311++G(2d,2p) level of theory, respectively. New alternative reaction mechanisms, to the one previously proposed (J. Phys. Chem. Lett. 2013, 4, 2525) have been found. The lower barrier of the new mechanism shows that it is easy for H2COO + O3 to dissociate to formaldehyde and oxygen. For the reactions of H2CO with O3 to produce H2COO and O2, we find relatively high energy barriers, which makes the ozone dissociation to oxygen unlikely to be catalyzed by CI.
Instrumental Crispness and Crunchiness of Roasted Hazelnuts and Correlations with Sensory Assessment (1999)

ABSTRACT Crispness and crunchiness of 15 samples of roasted hazelnuts were investigated. Force deformation curves from compression cell testing were analyzed and mechanical response variables were determined for roasted hazelnuts. Regression equations based on roasting air temperature, air velocity, and roasting time explained (R 2 _0.9 –0.98, p &lt; 0.001) the mechanical response variables. Samples were also evaluated by a quantitative descriptive panel. Among the mechanical response variables, the first fracture point (F 1 ) observed on the force deformation curve and the slope (S 2 ) for the line between the first and second fracture points strongly correlated (inverse) with sensory crispness (R =–0.96) and crunchiness (R _–0.92), respectively.
Cardiovascular Response Patterns to Sympathetic Stimulation by Central Hypovolemia (2016)

In healthy subjects, variation in cardiovascular responses to sympathetic stimulation evoked by submaximal lower body negative pressure (LBNP) is considerable. This study addressed the question whether inter-subject variation in cardiovascular responses coincides with consistent and reproducible responses in an individual subject. In 10 healthy subjects (5 female, median age 22 years), continuous hemodynamic parameters (finger plethysmography; Nexfin, Edwards Lifesciences), and time-domain baroreflex sensitivity (BRS) were quantified during three consecutive 5-min runs of LBNP at -50 mmHg. The protocol was repeated after 1 week to establish intra-subject reproducibility. In response to LBNP, 5 subjects (3 females) showed a prominent increase in heart rate (HR; 54 ± 14%, p = 0.001) with no change in total peripheral resistance (TPR; p = 0.25) whereas the other 5 subjects (2 females) demonstrated a significant rise in TPR (7 ± 3%, p = 0.017) with a moderate increase in HR (21 ± 9%, p = 0.004). These different reflex responses coincided with differences in resting BRS (22 ± 8 vs. 11 ± 3 ms/mmHg, p = 0.049) and resting HR (57 ± 8 vs. 71 ± 12 bpm, p = 0.047) and were highly reproducible over time. In conclusion, we found distinct cardiovascular response patterns to sympathetic stimulation by LBNP in young healthy individuals. These patterns of preferential autonomic blood pressure control appeared related to resting cardiac BRS and HR and were consistent over time.
Construction of mini-Tn10luxABcam/Ptac-ATS and its use for developing a bacteriophage that transduces bioluminescence to Escherichia coli O157:H7 (2000)

Mini-Tn10luxABcam/Ptac-ATS was constructed in order to develop a luciferase-transducing bacteriophage for detecting Escherichia coli O157:H7. The transposon was designed to deliver a 3.6-kb insertion that confers n-decanal-dependent bioluminescence and resistance to chloramphenicol and was constructed using mini-Tn10cam/Ptac-ATS in the plasmid pNK2884 and luxAB from Vibrio harveyi. ΦV10, a temperate bacteriophage infecting common phage types of Escherichia coli O157:H7, was mutagenized as a prophage in E. coli O157:H7 strain R508. ΦV10::luxABcamA1-23 was rescued from the strain by propagating it on a strain lacking the bacteriophage and the vector containing the transposon. The bacteriophage transduced n-decanal-dependent bioluminescence to E. coli O157:H7 strain R508 that was measurable approximately 1 h post infection.
Multiresolution inpainting for reconstruction of missing data in VHR images (2011)

Reconstructing missing data in very high resolution (VHR) multispectral images represents a complex image processing challenge. In this paper, we face this problem through a novel solution based on inpainting. Inpainting is a technique to reconstruct missing regions in a given image by propagating the spectro-geometrical information retrieved from the remaining parts of the image. Our proposed solution relies on the idea to formulate the inpainting process under a multiresolution processing scheme. Experiments conducted on a VHR image are reported and discussed.
2D to 3D Structural Transformation of Calcium Oxalate Revealed by In Situ Graphene Liquid Cell TEM (2022)

Journal Article 2D to 3D Structural Transformation of Calcium Oxalate Revealed by In Situ Graphene Liquid Cell TEM Get access Lioudmila V Sorokina, Lioudmila V Sorokina Department of Civil, Materials, and Environmental Engineering, University of Illinois at Chicago, Chicago, IL, United States Search for other works by this author on: Oxford Academic Google Scholar Abhijit H Phakatkar, Abhijit H Phakatkar Department of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL, United States Search for other works by this author on: Oxford Academic Google Scholar Reza Shahbazian-Yassar, Reza Shahbazian-Yassar Department of Civil, Materials, and Environmental Engineering, University of Illinois at Chicago, Chicago, IL, United StatesDepartment of Mechanical Engineering, University of Illinois at Chicago, Chicago, IL, United States Search for other works by this author on: Oxford Academic Google Scholar Tolou Shokuhfar Tolou Shokuhfar Department of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL, United StatesDepartment of Mechanical Engineering, University of Illinois at Chicago, Chicago, IL, United States Corresponding author: tolou@uic.edu Search for other works by this author on: Oxford Academic Google Scholar Microscopy and Microanalysis, Volume 28, Issue S1, 1 August 2022, Pages 1834–1836, https://doi.org/10.1017/S143192762200722X Published: 01 August 2022
Book Review: Fremdheit und Reisen im Mittelalter (1998)

Book Review: Fremdheit und Reisen im Mittelalter Get access George Gillespie George Gillespie University of Wales Search for other works by this author on: Oxford Academic Google Scholar German History, Volume 16, Issue 3, July 1998, Pages 427–428, https://doi.org/10.1177/026635549801600311 Published: 01 July 1998
The MPEG-4 Book (2002)

From the Publisher:
The most complete, focused guide to MPEG-4the breakthrough standard for interactive multimedia.

The comprehensive, focused, up-to-the-minute guide to MPEG-4
Practical solutions for next-generation multimedia applications 
In-depth coverage of natural and synthetic audiovisual object coding, description, composition and synchronization
Binary and textual scene description
Transport and storage of MPEG-4 content
MPEG-4 profiles and levels; verification tests


MPEG-4 represents a breakthrough in multimedia, delivering not just outstanding compression but also a fully interactive user experience. In The MPEG-4 Book, two leaders of the MPEG-4 standards community offer a comprehensive, targeted guide to the MPEG-4 standardand its use in cutting-edge applications. Fernando Pereira and Touradj Ebrahimi, together with a unique collection of key MPEG experts, demonstrate how MPEG-4 addresses tomorrow's multimedia applications more successfully than any previous standard. They review every element of the standard to offer you a book that covers: 

Synthetic and natural audio and video object coding, description and synchronization
BIFSthe MPEG-4 language for scene description and interaction 
The extensible MPEG-4 textual format XMT
Transport and delivery of MPEG-4 content
MPEG-J: using Java classes within MPEG-4 content
A complete overview of MPEG-4 Profiles and Levels
Verification tests


The authors also walk through the MPEG-4 Systems Reference Software ?offering powerful real-world insights for every product developer, softwareprofessional, engineer, and researcher involved with MPEG-4 and state-of-the-art multimedia delivery. 

Part of the new IMSC Press Series from the Integrated Multimedia System Center at the University of Southern California, a federally funded center specializing in cutting-edge multimedia research.
Expression of multidrug resistance gene (MDR-1) in human normal leukocytes. (1993)

mdr-1 is constitutively expressed in human normal leukocytes at levels that cannot significantly affect drug resistance. Accordingly, low-level mdr-1 expression in leukemic cells should not be considered a label of pleiotropic drug resistance.
09161 Abstracts Collection – Generalization of spatial information (2009)

From 13.04. to 17.04.2009, the Dagstuhl Seminar 09161 ``Generalization of spatial information '' was held in Schloss Dagstuhl~--~Leibniz Center for Informatics. During the seminar, several participants presented their current research, and ongoing work and open problems were discussed. Abstracts of the presentations given during the seminar as well as abstracts of seminar results and ideas are put together in this paper. The first section describes the seminar topics and goals in general. Links to extended abstracts or full papers are provided, if available.
FKBP12-ligand-calcineurin interactions: analogs of SBL506 (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFKBP12-ligand-calcineurin interactions: analogs of SBL506Mark FurberCite this: J. Am. Chem. Soc. 1995, 117, 27, 7267–7268Publication Date (Print):July 1, 1995Publication History Published online1 May 2002Published inissue 1 July 1995https://pubs.acs.org/doi/10.1021/ja00132a036https://doi.org/10.1021/ja00132a036research-articleACS PublicationsRequest reuse permissionsArticle Views90Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Gene cloning and characterization of a β-1,3(4)-glucanase from Penicillium sp. C6. (2013)

Bglc6,a glycoside hydrolase with 16 families' glucanase gene,was cloned from Penicillium sp.C6.The full-length of cDNA was 1 044 bp,including a putative signal peptide of 20 residues and a catalytic domain with glycosyl hydrolase of 16 families.The deduced amino acid sequence showed the highest identity(64%) with the putative endo-1,3(4)-β-glucanase from Grosmannia clavigera kw1407.The mature albumen BglC6 was successfully expressed in Pichia pastoris.The enzymatic characteristics analysis showed that the optimum pH and temperature for the recombinant glucanase BglC6 was pH 4.5 and 50℃.It exhibited good stability within acid pH range.When using barley β-glucan as substrate,the specific activity,Km and Vmax values were 253.8 U/mg,8.42 mg/mL and 478.4 μmol/min · mg,respectively.BglC6 had better resistance to majority metal ions.Therefore,this glucanase possess potential application in animal feed industry.
Cigarette Smoke-ExposedCandida albicansIncreased Chitin Production and Modulated Human Fibroblast Cell Responses (2014)

The predisposition of cigarette smokers for development of respiratory and oral bacterial infections is well documented. Cigarette smoke can also contribute to yeast infection. The aim of this study was to investigate the effect of cigarette smoke condensate (CSC) on C. albicans transition, chitin content, and response to environmental stress and to examine the interaction between CSC-pretreated C. albicans and normal human gingival fibroblasts. Following exposure to CSC, C. albicans transition from blastospore to hyphal form increased. CSC-pretreated yeast cells became significantly (P < 0.01) sensitive to oxidation but significantly (P < 0.01) resistant to both osmotic and heat stress. CSC-pretreated C. albicans expressed high levels of chitin, with 2- to 8-fold recorded under hyphal conditions. CSC-pretreated C. albicans adhered better to the gingival fibroblasts, proliferated almost three times more and adapted into hyphae, while the gingival fibroblasts recorded a significantly (P < 0.01) slow growth rate but a significantly higher level of IL-1β when in contact with CSC-pretreated C. albicans. CSC was thus able to modulate both C. albicans transition through the cell wall chitin content and the interaction between C. albicans and normal human gingival fibroblasts. These findings may be relevant to fungal infections in the oral cavity in smokers.
Disparate tendency of stress evolution of thin and thick electroplated Cu films at room temperature (2010)

The self-annealing effect of electroplated copper films was investigated by measuring the time dependence of the film stress for different film thicknesses between 1.5μm and 20μm. This recrystallization process results in significant microstructure change and a film-thickness-dependent stress evolution at room temperature. This behavior can be explained by the superposition of grain growth and grain size dependent yielding. Existing models have been used and improved to describe the mechanisms related to stress evolution.