gebhart/patrepeval huggingface dataset:
Evolutionary computation: comments on the history and current state (1997)

Evolutionary computation has started to receive significant attention during the last decade, although the origins can be traced back to the late 1950's. This article surveys the history as well as the current state of this rapidly growing field. We describe the purpose, the general structure, and the working principles of different approaches, including genetic algorithms (GA) (with links to genetic programming (GP) and classifier systems (CS)), evolution strategies (ES), and evolutionary programming (EP) by analysis and comparison of their most important constituents (i.e. representations, variation operators, reproduction, and selection mechanism). Finally, we give a brief overview on the manifold of application domains, although this necessarily must remain incomplete.
Modeling of a High-Temperature-Serpentine External Tubular Receiver Using Supercritical CO2 (2014)

This paper describes the modelling and design of an external receiver using supercritical CO2 as the heat transfer fluid that can reach up to 700 °C outlet temperature with ∼85% thermal efficiency. The internal pressure of the tubes is 20 MPa. The receiver tubes are arranged in a serpentine fashion and are coated with Pyromark 2500. Analyses were performed to evaluate the thermal efficiency of the receiver as a function of incidence angle of the incident radiation. Two different radiation models, discrete ordinates and surface-to-surface ray tracing, were used in the computational fluid dynamics model (ANSYS FLUENT). The receiver thermal efficiency ranged from 75% for incidence angles of 80 degrees to 88% for near-normal incidence angles of 10 degrees.
The rat melanin-concentrating hormone gene encodes an additional putative protein in a different reading frame. (1996)

The sequence of a novel melanin-concentrating hormone (MCH) transcript, composed of precisely joined exon I and exon III of the MCH gene, has been elucidated by RT-PCR analysis of hypothalamic RNA isolated from different rat strains. The deduced amino acid sequence predicted that it encodes in the exon I the same N-terminal moiety as MCH precursor part but diverges downstream, exon III being translated in a different reading frame than the MCH mRNA. This putative chimeric protein has been named MCH(M)-gene(G)-overprinted (O)-polypeptide(P). A peptide of 14 amino acids could be generated after cleavage at a basic site. Immunocytochemistry studies, using MGOP- and MCH-specific antisera, revealed overlapping expression in the dorsolateral hypothalamus. This suggests that MGOP or derived peptide(s) would participate in modulating the effect of pro-MCH generated peptides in the rat brain.
Electrocochleography in cochlear implantation: Development, applications, and future directions (2020)

Electrocochleography (ECochG) is an electrophysiological technique that records electrical potentials generated by different components of the inner ear and peripheral cochlear nerve in response to acoustic stimulation. ECochG responses can be analyzed into (1) cochlear microphonics (CM), (2) auditory nerve neurophonics, (3) summating potential, and (4) compound action potential. Over the past few decades, there have been ongoing refinements in technique and updates in the understanding of recorded potentials. Historically, ECochG found its main application in the diagnostic evaluation of Meniere's disease (MD). However, in the last decade, the focus has shifted towards cochlear implantation (CI). In patients with residual hearing after CI, combined electric and acoustic stimulation has resulted in improved hearing and speech outcomes. Despite efforts to mitigate trauma during electrode insertion, hearing preservation rates vary after surgery. During implantation, real‐time ECochG offers an opportunity to measure frequency specific CMs elicited from a localized region in the cochlea as the surgeon inserts the electrode array. In extracochlear ECochG recordings, the recording electrode can be placed on the promontory, the stapes, or the tympanic membrane. Intracochlear ECochG can be performed by inserting a recording electrode into the cochlea or by using one of the CI electrodes as the recording electrode. The loss of intraoperative ECochG signal may indicate cochlear trauma from electrode insertion, but the association between intraoperative ECochG changes and cochlear trauma remains controversial. The ability to monitor cochlear trauma during CI electrode placement holds promise to improve hearing preservation outcomes, modify surgical techniques, and change electrode design. The goal of this review is to provide a comprehensive overview of the electrophysiology and history of ECochG, discuss its recent applications in CI, and explore the ongoing research in this expanding field.
Temperature dependence of the zero-phonon linewidth in quantum dots: An effect of the fluctuating environment (2007)

We report systematic measurements on the broadening of the emission spectrum of single quantum dots as a function of temperature and incident power. Spectral diffusion effects in the motional narrowing regime provide a quantitative interpretation of our experimental results. We show that, at low incident power, the thermal activation of spectral diffusion results in a Lorentzian zero-phonon line with a width that increases linearly with temperature. Our study provides a unified interpretation to the widely debated issue of the dispersion of the data on the temperature dependence of this zero-phonon linewidth. Our explanation is based on an original model where acoustic phonons interact with carriers outside the quantum dot.
ChemInform Abstract: Synthesis of 6,6‐d2‐Dehydroabietic Acid. (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Pharmacokinetics, plasma protein binding and urinary excretion of Nω‐nitro‐L‐arginine in rats (1994)

The in vivo disposition of N ω ‐nitro‐ l ‐arginine ( l ‐NOARG) has been examined in rats. Plasma concentrations of l ‐NOARG following an intravenous dose of 10 mg kg −1 were determined by high‐performance liquid chromatography. Plasma l ‐NOARG concentrations declined biexponentially, with average half‐lives of 11 min and 20 h. l ‐NOARG clearance did not appear to exhibit concentration‐dependency below a plasma concentration of 4.56 × 10 −4 m (100 mg 1 −1 ). Ultrafiltration studies revealed insignificant binding of l ‐NOARG to rat plasma proteins. Urinary excretion of unchanged l ‐NOARG was minimal. These pharmacokinetic information may be useful in the design of in vivo experiments involving l ‐NOARG, as well as in the interpretation of the pharmacodynamics of this important nitric oxide synthase inhibitor.
On the Evaluation of Semantic Phenomena in Neural Machine Translation\n Using Natural Language Inference (2018)

We propose a process for investigating the extent to which sentence\nrepresentations arising from neural machine translation (NMT) systems encode\ndistinct semantic phenomena. We use these representations as features to train\na natural language inference (NLI) classifier based on datasets recast from\nexisting semantic annotations. In applying this process to a representative NMT\nsystem, we find its encoder appears most suited to supporting inferences at the\nsyntax-semantics interface, as compared to anaphora resolution requiring\nworld-knowledge. We conclude with a discussion on the merits and potential\ndeficiencies of the existing process, and how it may be improved and extended\nas a broader framework for evaluating semantic coverage.\n
CO2-Responsive Pickering Emulsions Stabilized by a Bio-based Rigid Surfactant with Nanosilica (2018)

A novel CO<sub>2</sub>-responsive surfactant, maleopimaric acid glycidyl methacrylate ester 3-(dimethylamino)propylamine imide (MPAGN), based on sustainable resource of rosin was synthesized and used to prepare a kind of CO<sub>2</sub>-responsive Pickering emulsions with nanosilica. MPAGN can be reversibly responsive to CO<sub>2</sub> and N<sub>2</sub> between active cationic (MPAGNH<sup>+</sup>) and inactive nonionic (MPAGN), leading to adsorb on or desorb from the surface of nanosilica, then stabilize or break emulsion. CO<sub>2</sub>-responsive behavior of MPAGN was verified by cycle change of pH and conductivity with bubbling CO<sub>2</sub> and N<sub>2</sub> alternately. The type of adsorption of MPAGNH<sup>+</sup> at the particle-water interface was explained according to the adsorption isotherms. The mechanisms of stabilization, destabilization, and restabilization of Pickering emulsion were analyzed according to zeta potentials and droplet size. This Pickering emulsion can be reversible between stable and unstable by bubbling CO<sub>2</sub> and N<sub>2</sub> alternately. Moreover, this emulsifier can be recycled when new oil was added after removing the initial oil. Therefore, it not only has economic benefits but also has an environmentally friendly property.
Heparan sulfate–dependent ERK activation contributes to the overexpression of fibrotic proteins and enhanced contraction by scleroderma fibroblasts (2008)

The results of this study suggest that heparan sulfate-dependent ERK activation contributes to the enhanced contractile ability demonstrated by dermal fibroblasts from lesional skin of patients with scleroderma. These results are consistent with the notion that the MEK/ERK procontractile pathway is dysregulated in scleroderma dermal fibroblasts. Additionally, the results suggest that antagonizing the MEK/ERK pathway is likely to modulate heparan sulfate proteoglycan activity, which in turn may have a profound effect on the fibrotic response in SSc.
Multiuser detection in asynchronous on-off random access channels using lasso (2010)

This paper considers on-off random access channels where users transmit either a one or a zero to a base station. Such channels represent an abstraction of control channels used for scheduling requests in third-generation cellular systems and uplinks in wireless sensor networks deployed for target detection. This paper introduces a novel convex-optimization-based scheme for multiuser detection (MUD) in asynchronous on-off random access channels that does not require knowledge of the delays or the instantaneous received signal-to-noise ratios of the individual users at the base station. For any fixed number of temporal signal space dimensions N and maximum delay τ in the system, the proposed scheme can accommodate M ≲ exp(O(N <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1/3</sup> )) total users and k ≲ N/ log M active users in the system-a significant improvement over the k ≤ M ≲ N scaling suggested by the use of classical matched-filtering-based approaches to MUD employing orthogonal signaling. Furthermore, the computational complexity of the proposed scheme differs from that of a similar oracle-based scheme with perfect knowledge of the user delays by at most a factor of log(N+τ). Finally, the results presented in here are non-asymptotic, in contrast to related previous work for synchronous channels that only guarantees that the probability of MUD error at the base station goes to zero asymptotically in M.
Predicting suicidal and self-injurious events in a correctional setting using AI algorithms on unstructured medical notes and structured data (2023)

Suicidal and self-injurious incidents in correctional settings deplete the institutional and healthcare resources, create disorder and stress for staff and other inmates. Traditional statistical analyses provide some guidance, but they can only be applied to structured data that are often difficult to collect and their recommendations are often expensive to act upon. This study aims to extract information from medical and mental health progress notes using AI algorithms to make actionable predictions of suicidal and self-injurious events to improve the efficiency of triage for health care services and prevent suicidal and injurious events from happening at California's Orange County Jails. The results showed that the notes data contain more information with respect to suicidal or injurious behaviors than the structured data available in the EHR database at the Orange County Jails. Using the notes data alone (under-sampled to 50%) in a Transformer Encoder model produced an AUC-ROC of 0.862, a Sensitivity of 0.816, and a Specificity of 0.738. Incorporating the information extracted from the notes data into traditional Machine Learning models as a feature alongside structured data (under-sampled to 50%) yielded better performance in terms of Sensitivity (AUC-ROC: 0.77, Sensitivity: 0.89, Specificity: 0.65). In addition, under-sampling is an effective approach to mitigating the impact of the extremely imbalanced classes.
Antiviral Activity of the Human Cathelicidin, LL-37, and Derived Peptides on Seasonal and Pandemic Influenza A Viruses (2015)

Human LL-37, a cationic antimicrobial peptide, was recently shown to have antiviral activity against influenza A virus (IAV) strains in vitro and in vivo. In this study we compared the anti-influenza activity of LL-37 with that of several fragments derived from LL-37. We first tested the peptides against a seasonal H3N2 strain and the mouse adapted H1N1 strain, PR-8. The N-terminal fragment, LL-23, had slight neutralizing activity against these strains. In LL-23V9 serine 9 is substituted by valine creating a continuous hydrophobic surface. LL-23V9 has been shown to have increased anti-bacterial activity compared to LL-23 and we now show slightly increased antiviral activity compared to LL-23 as well. The short central fragments, FK-13 and KR-12, which have anti-bacterial activity did not inhibit IAV. In contrast, a longer 20 amino acid central fragment of LL-37 (GI-20) had neutralizing activity similar to LL-37. None of the peptides inhibited viral hemagglutination or neuraminidase activity. We next tested activity of the peptides against a strain of pandemic H1N1 of 2009 (A/California/04/09/H1N1 or "Cal09"). Unexpectedly, LL-37 had markedly reduced activity against Cal09 using several cell types and assays of antiviral activity. A mutant viral strain containing just the hemagglutinin (HA) of 2009 pandemic H1N1 was inhibited by LL-37, suggested that genes other than the HA are involved in the resistance of pH1N1. In contrast, GI-20 did inhibit Cal09. In conclusion, the central helix of LL-37 incorporated in GI-20 appears to be required for optimal antiviral activity. The finding that GI-20 inhibits Cal09 suggests that it may be possible to engineer derivatives of LL-37 with improved antiviral properties.
Modeling of the Anodic Arc Discharge and Conditions for Single-Wall Carbon Nanotube Growth (2006)

A model of the arc discharge used for a single wall carbon nanotube (SWNT) synthesis is developed. Coupling solution of the non-equilibrium, Knudsen layer, with hydrodynamic layer and discharge column provides self-consistent solution for the ablation rate and plasma parameter distribution. It is predicted that the interelectrode gap decreases with the background pressure increase. Conditions for single wall carbon nanotube formation in the arc discharge method of nanotube synthesis are described. Carbon nanotube seed formation and charging in the interelectrode gap are found to be very important effects that may alter carbon nanotube formation in the cathode region. This model predicts that the long carbon nanotubes in the high pressure Helium environment can be deposited on the cathode surface. Model predictions are found to be in agreement with experiment.
Regulation of Prolactin Secretion by Dopamine at the Level of the Hypothalamus in the Turkey (2002)

Avian prolactin (PRL) secretion is regulated by vasoactive intestinal peptide (VIP) neurons residing in the infundibular nuclear complex (INF) of the hypothalamus. This VIPergic activity is modulated by stimulatory dopaminergic inputs. Dynorphin, serotonin (5-HT), dopamine (DA) and VIP all appear to stimulate PRL secretion along a hypothalamic pathway, expressing kappa opioid, serotonergic, dopaminergic and VIPergic receptors in succession, with the VIPergic system as the final mediator. Electrical stimulation (ES) within the turkey hypothalamus at the level of the medial preoptic area (POA), the ventromedial hypothalamic nucleus (VMN), the INF or the median eminence (ME) results in the release of PRL. When the selective D(1) DA receptor antagonist SCH-23390 HCl was infused intraventricularly at the rate of 10 nmol/min, ES in the POA or VMN was unable to increase PRL levels, while ES in the INF and ME did increase PRL to the same level as that of controls. These results were interpreted to suggest that the D(1) DA receptors involved in PRL release lie caudally to the VMN and dorsally to the INF. Bilateral microinjections (50 ng) of the D(1) DA receptor agonist SKF-38393 HCl into the POA or VMN failed to produce any increase in PRL, while similar microinjections in the INF increased PRL significantly within 15 min. Bilateral microinjections of the D(1) DA antagonist (50 ng) into the INF blocked the rise in PRL associated with ES in the POA. Bilateral microinjections of a D(2) DA antagonist (50 ng) into the INF failed to block PRL secretion induced by ES in the POA. Tract tracing, using double-label immunocytochemistry, revealed the presence of a monosynaptic dopaminergic pathway projecting from the POA to the INF. These data imply that the only hypothalamic D(1) DA receptors involved in the regulation of avian PRL secretion are those residing within the INF in the same region as the VIP neurons known to be involved in PRL secretion.
Hot-electron-induced MOSFET degradation&#8212;Model, monitor, and improvement (1985)

Evidence suggests that MOSFET degradation is due to interface-states generation by electrons having 3.7 eV and higher energies. This critical energy and the observed time dependence is explained with physical model involving the breaking of the ≡ Si <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">s</inf> H bonds. The device lifetime τ is proportional to <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">I_{sub}^{-2.9}I_{d}^{1.9}\Delta V_{t}^{1.5}</tex> . If I <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">sub</inf> is large because of small <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">L</tex> or large V <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">d</inf> , etc., τ will be small. I <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">sub</inf> (and possibly light emission) is thus a powerful predictor of τ. The proportionality constant has been found to vary by a factor of 100 for different technologies, offering hope for substantially better reliability through future improvements in dielectric /interface technologies. A simple physical model can relate the channel field E <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">m</inf> to all the device parameters and bias voltages. Its use in interpreting and guiding hot-electron scaling are described. LDD structures can reduce E <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">m</inf> and I <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">sub</inf> and, when properly designed, reduce device degradation.
Magnetic property of NiO ultrafine particles with a small Ni core (1997)

The magnetic nature of a NiO shell and a Ni core were separately investigated in the temperature dependence of the magnetization curve of the samples with the average sizes of 1.6, 2.0, 2.2, 2.5, 2.8, 3.0 and 3.2 nm. The superparamagnetism of the NiO shell and Ni core were observed in specific temperature ranges. The increase of the magnetic moment per atom in the metallic free cluster with decreasing size were not observed in the small Ni core with the NiO shell though the proper saturation magnetization of Ni core was estimated.
Interpolated lattice Boltzmann boundary conditions for surface reaction kinetics (2010)

This paper describes a method for implementing surface reaction kinetics in lattice Boltzmann simulations. The interpolated boundary conditions are capable of simulating surface reactions and dissolution at both stationary and moving solid-fluid and fluid-fluid interfaces. Results obtained with the boundary conditions are compared to analytical solutions for first-order and constant-flux kinetic surface reactions in a one-dimensional half space, as well as to the analytical solution for evaporation from the surface of a cylinder. Excellent agreement between analytical and simulated results is obtained for a wide range of diffusivities, lattice velocities, and surface reaction rates. The boundary model's ability to represent dissolution in binary fluid mixtures is demonstrated by modeling diffusion from a rising bubble and dissolution of a droplet near a flat plate.
Linear reflectarray antenna design using 1-bit digital phase shifters (2009)

In this paper, design of reflectarray antennas using 1-bit digital phase shifters is reported. Using quadratic phase distribution due to the incident spherical field on the array face, the quantization error caused by 1-bit phase shifters is compensated. The results are compared with 1.5 and 2 bits phase shifters and effects of frequency squint, number of quantization bits and number of elements on radiation parameters such as scan angle error, directivity and side lobe are discussed. Finally, the study of quantization error variation with respect to radiating source position is presented.
Processes for multi-layer devices utilizing layer transfer (2023)

A method includes forming a release layer over a donor substrate. A plurality of devices made of a first semiconductor material are formed over the release layer. A first dielectric layer is formed over the plurality of devices such that all exposed surfaces of the plurality of devices are covered by the first dielectric layer. The plurality of devices are chemically attached to a receiving device made of a second semiconductor material different than the first semiconductor material, the receiving device having a receiving substrate attached to a surface of the receiving device opposite the plurality of devices. The release layer is etched to release the donor substrate from the plurality of devices. A second dielectric layer is applied over the plurality of devices and the receiving device to mechanically attach the plurality of devices to the receiving device.
The AXES PRO video search system (2013)

We demonstrate a multimedia content information retrieval engine developed for audiovisual digital libraries targeted at media professionals. It is the first of three multimedia IR systems being developed by the AXES project. The system brings together traditional text IR and state-of-the-art content indexing and retrieval technologies to allow users to search and browse digital libraries in novel ways. Key features include: metadata and ASR search and filtering, on-the-fly visual concept classification (categories, faces, places, and logos), and similarity search (instances and faces).