gebhart/patrepeval huggingface dataset:
Verifiable Secret Share for file storage with cheater identification (2020)

Verifiable Secret Share (VSS) is a branch of Secret Share (SS) that allow Verifiable Secret Share (VSS) is a branch of Secret Share (SS) that allows verifying the correctness of recomposed files. VSS techniques usually check the correctness of secrets at the end of the re-composition process, therefore, in case of errors, a lot of computational resources and time are wasted. In this paper, we propose an innovative VSS model that is able to verify the correctness of SS fragments before the ending of the recomposition task, thus increasing efficiency and response time. The basic idea behind the proposed approach is to make use of a Hash function to validate fragments, thus to decide if the recomposition task can be performed or not. The experimental result validates our model and proves its applicability in distributed storage systems.
Analysis of balanced and unbalanced faults in power systems using dynamic phasors (2003)

This paper extends dynamic phasor models for major elements from single-phase to 3-phase. This kind of 3-phase model can be used to simulate balanced and unbalanced faults conveniently. These models include generator, transmission line (lumped parameter), inductor, and capacitor etc. Among these models, models of transmission line (lumped parameter), inductor and capacitor keep fundamental components of time-varying Fourier coefficients, which are based on generalized averaging method. As for generator's model, we use the Park model, the negative-sequence equivalent circuit and zero-sequence equivalent circuit to compute the positive-sequence, negative-sequence and zero-sequence components, respectively. Furthermore, we considered phasor dynamics of negative-sequence and zero-sequence. These models are "quasi-accurate" models compared with "EMTP-like" models, and are more accurate than "quasistationary" models. All of our models are tested using 3-node network. By comparing our results with the ones from EMTP and PSASP, it is proved, this kind of 3-phase dynamic phasor models has higher precision than "quasi-stationary" models, and it is a middle-kind model between standard time-domain models and "quasistationary" models.
A real-time laser-based detection system for measurement of delineations of moving vehicles (2001)

In current practice, quantitative traffic data are most commonly acquired from inductive loops. In addition, video-image processing or time-of-flight laser systems can be used. These methods all have problems associated with them. We have developed a nonintrusive laser-based detection system for measurement of vehicle travel time. The basic detector unit consists of a fan angle laser and a photodetector array positioned above the plane of detection. This detection system is able to determine the length and width of moving objects in real time with high resolution, with the highest resolution measurements being associated with object lengths. This information is used to differentiate similar objects and can be used later for re-identification of individual objects or object groups, providing a real measure of travel time between detection sites.
Site‐specific T – DNA integration in A rabidopsis thaliana mediated by the combined action of CRE recombinase and ϕ C 31 integrase (2013)

Random T-DNA integration into the plant host genome can be problematic for a variety of reasons, including potentially variable transgene expression as a result of different integration positions and multiple T-DNA copies, the risk of mutating the host genome and the difficulty of stacking well-defined traits. Therefore, recombination systems have been proposed to integrate the T-DNA at a pre-selected site in the host genome. Here, we demonstrate the capacity of the ϕC31 integrase (INT) for efficient targeted T-DNA integration. Moreover, we show that the iterative site-specific integration system (ISSI), which combines the activities of the CRE recombinase and INT, enables the targeting of genes to a pre-selected site with the concomitant removal of the resident selectable marker. To begin, plants expressing both the CRE and INT recombinase and containing the target attP site were constructed. These plants were supertransformed with a T-DNA vector harboring the loxP site, the attB sites, a selectable marker and an expression cassette encoding a reporter protein. Three out of the 35 transformants obtained (9%) showed transgenerational site-specific integration (SSI) of this T-DNA and removal of the resident selectable marker, as demonstrated by PCR, Southern blot and segregation analysis. In conclusion, our results show the applicability of the ISSI system for precise and targeted Agrobacterium-mediated integration, allowing the serial integration of transgenic DNA sequences in plants.
Oral tranexamic acid for an additional 24 hours postoperatively versus a single preoperative intravenous dose for reducing blood loss in total hip arthroplasty: results of a randomized controlled trial (TRAC-24) (2021)

The addition of oral TXA for 24 hours postoperatively does not reduce blood loss beyond that achieved with a single 1 g IV perioperative dose alone. There may be a clinically relevant difference in patients with a normal BMI, which warrants further investigation. Critically, there were no safety issues in patients with a history of thromboembolic, cardiovascular, or cerebrovascular disease. Cite this article: <i>Bone Joint J</i> 2021;103-B(7):1197-1205.
Generating color-coded anatomic muscle maps for correlation of quantitative magnetic resonance imaging analysis with clinical examination in neuromuscular disorders (2013)

This approach can be applied in any neuromuscular disorder where muscle function is assessed by clinical or imaging scores.
Poly(Ethylene Glycol) in Drug Delivery, Why Does it Work, and Can We do Better? All Atom Molecular Dynamics Simulation Provides Some Answers (2012)

We summarize our recent work, using all atom molecular dynamics simulation to study the role of poly(ethylene glycol) (PEG) in drug delivery. We have simulated the drug delivery liposome membrane, in both the Gel and Liquid crystalline states. The simulations of the PEGylated membrane have been carried out in the presence of a physiological concentration of NaCl, and two other salts encountered in physiological conditions, KCL and CaCl2. We also simulated targeting moieties on the PEGylated membrane, comparing the behavior of two targeting moieties. We also simulated PEG with three drug molecules for which it is used as a delivery aid: paclitaxel, piroxicam, and hematoporphyrin. We found that the specific properties of PEG, its solubility in both polar and non-polar solvents, and its acting as a polymer electrolyte, have a significant e_ect on its behavior when used in drug delivery.
Crop Ferality and Volunteerism (2005)

At a time when much of humanity is already but one failed harvest removed from starvation, we cannot afford to ignore any potential danger to food security, especially when that danger poses a threat to rice, the staff of life for so much of the world. Crop Ferality and Volunteerism brings together research pioneers from various disciplines
Piloted Simulator Evaluation Results of Flight Physics Based Stall Recovery Guidance (2018)

In recent studies, it has been observed that loss of control in flight is the most frequent primary cause of accidents. A significant share of accidents in this category can be remedied by upset prevention if possible, and by upset recovery if necessary, in this order of priorities. One of the most important upsets to be recovered from is stall. Recent accidents have shown that a correct stall recovery maneuver remains a big challenge in civil aviation, partly due to a lack of pilot training. A possible strategy to support the flight crew in this demanding context is calculating a recovery guidance signal, and showing this signal in an intuitive way on one of the cockpit displays, for example by means of the flight director. Different methods for calculating the recovery signal, one based on fast model predictive control and another using an energy based approach, have been evaluated in four relevant operational scenarios by experienced commercial as well as test pilots in the Vertical Motion Simulator at NASA Ames Research Center. Evaluation results show that this approach could be able to assist the pilots in executing a correct stall recovery maneuver.
Recent Clinical and Investigational Applications of Fibrin Sealant in Selected Surgical Specialties (2006)

*Division of Urology, Department of Surgery, Duke University Medical Center, Durham, NC. †Division of Vascular Surgery, Department of Surgery, Duke University Medical Center, Durham, NC. *Correspondence address: David M Albala, MD, FACS, Division of Urology, Department of Surgery, Duke University Hospital, DUMC# 3457, Erwin Rd, Durham, NC 27710. Received October 5, 2005; Revised November 21, 2005; Accepted November 30, 2006. Competing Interests Declared: DM Albala and JH Lawson have served on an advisory board for Johnson & Johnson Wound Management, a division of Ethicon, Inc.
Analysis of the efficiency of intensity measures from real earthquake data recorded in buildings (2021)

In this paper, a number of spectral and ordinary ground motion intensity measures (IMs) are tested for use in structural performance assessment. Real strong motion values recorded at the top and the bottom of US, Japanese and Romanian buildings are analyzed in order to identify the source of uncertainties in the prediction of engineering demand parameters (i.e. structural drift) for given IMs (i.e. σEDP|IM). The efficiency and sufficiency of each IM from a large set of building and earthquake motion data are tested for different criteria characterizing the seismic source (magnitude and source-to-site distance), and considering several building classes and a specific single-building analysis including aging due to cumulative earthquake damage over time. The spectral values at co-seismic resonance frequencies was found to be the most efficient IMs for the range of buildings and earthquakes investigated, particularly for velocity with a reduction of approximately 50% of the σEDP|IM value. Conversely, most IMs are relatively insufficient.
<title>Head-mounted computer interface based on eye tracking</title> (1993)

A head-mounted computer interface using eye-tracking as a `pointer' was demonstrated at the Third Annual Weapons Technology Review and Training Exposition at San Diego in January 1992, and is under further development for military and civilian applications. in this interface, the computer interprets eye gaze direction just as it would input from a mouse or trackball. This technology makes possible computer-human interaction with many ideal aspects: complete portability, hands-free operation, silent, secure operation anywhere and any time. Commercial systems using control inputs from the tracked eye are available and effective within their limits, but size, weight, and cost have been barriers to wider use. This paper describes the latest head-mounted eye tracking display (HETD) development prototype. We are exploring the technological limits of current and near-term lighting, detector, and lens technology to project the feasibility of this device.
Establishing population distribution of drug‐metabolizing enzyme activities for the use of salivary caffeine as a dynamic liver function marker in a Singaporean Chinese population (2016)

The salivary paraxanthine/caffeine molar ratio has been proposed as a novel dynamic liver function test to guide dose adjustments of drugs hepatically cleared by CYP1A2. Its usability requires an established population norm as well as the factors influencing the ratio and actual concentrations. To address this knowledge gap, salivary caffeine and paraxanthine concentrations were measured at 4 h post caffeine dose in healthy Chinese individuals who had undergone 24 h of caffeine abstinence. The metabolic ratio was calculated and statistical analysis was performed. From the 52 participants (26 males; 30 regular caffeine consumers) recruited, the salivary paraxanthine/caffeine molar ratio was normally distributed with a mean and SD of 0.5 ± 0.2. No statistically significant factors (BMI, body weight, gender and regularity of caffeine intake) affecting the metabolic ratio were found. The caffeine concentration and total caffeine plus paraxanthine concentrations were lower in males than in females, and lower in regular caffeine consumers than in non-regular caffeine consumers. The 4 h salivary metabolic ratio (mean: 0.5) was generally not significantly different from the literature reported salivary, serum and plasma ratios measured at 4-9 h in healthy individuals (mean range 0.4-0.7) but was significantly higher than the literature reported 6 h plasma ratio and salivary ratios measured at 1-6 h in patients with liver disease or mild abnormal liver function tests (mean range 0.03-0.2). Overall, the population norm of the salivary metabolic ratio in a Singaporean Chinese population established in this study is distinct from individuals with liver disease or mild abnormal liver function tests and provides the benchmark for dosage adjustments of drugs metabolized by CYP1A2. Copyright © 2016 John Wiley & Sons, Ltd.
Information rendezvous (1998)

This paper proposes a new type of asynchronous group communication tool called an information rendezvous system. The purpose of the system is to mediate between producers and consumers of information. Among other attributes, information rendezvous systems rely on the knowledge of the user community in determining the relevance of information. We also two describe two prototypes that demonstrate the feasibility of the information rendezvous concept.
ST 789 and ST 789 analogs: synthesis and analytical profile. (1992)

The procedure followed for the preparation of ST 789 and a series of origin derivatives analogs to ST 789 are described. A complete analytical profile of ST 789 and a concise profile of its analogs are also reported, together the purification methods applied.
Calcium phosphate cements for bone engineering and their biological properties (2017)

Calcium phosphate cements (CPCs) are frequently used to repair bone defects. Since their discovery in the 1980s, extensive research has been conducted to improve their properties, and emerging evidence supports their increased application in bone tissue engineering. Much effort has been made to enhance the biological performance of CPCs, including their biocompatibility, osteoconductivity, osteoinductivity, biodegradability, bioactivity, and interactions with cells. This review article focuses on the major recent developments in CPCs, including 3D printing, injectability, stem cell delivery, growth factor and drug delivery, and pre-vascularization of CPC scaffolds via co-culture and tri-culture techniques to enhance angiogenesis and osteogenesis.
Using polymeric precipitation inhibitors to improve the absorption of poorly water-soluble drugs: A mechanistic basis for utility (2010)

The inclusion of certain polymers within solid dispersion or lipid-based formulations can maintain drug supersaturation after dispersion and/or digestion of the vehicle, leading to improvements in bioavailability and variability in exposure. This review presents an overview of the fundamental principles that underpin drug precipitation mechanisms, describes the mechanisms by which precipitation may be inhibited, discusses the methods that can be used to identify polymeric precipitation inhibitors (PPIs), and summarizes current literature evidence of the most effective PPIs. Preliminary data from our laboratory is also presented, which describes the precipitation inhibition behavior of 53 polymeric materials using supersaturated solutions of danazol as a model, poorly water-soluble drug. These studies identify a group of PPIs with superior precipitation inhibition qualities, the majority of which are cellulose-based. These new results in combination with previous published data indicate that PPIs represent an appealing new technology with the potential to improve drug absorption for poorly water-soluble drugs. The molecular determinants of polymer utility, however, remain relatively poorly understood, although the cellulose derivates appear, in general, to provide the most benefit. More detailed studies are therefore required to define the parameters that most effectively predict and quantify the drug-polymer relationships that control precipitation inhibition.
Pharmacokinetics and bioavailability of midazolam in man. (1983)

The pharmacokinetic behaviour and the bioavailability of midazolam were investigated in six volunteers after intravenous (0.15 mg/kg) and oral administration (10, 20 and 40 mg). Following rapid intravenous injection of midazolam, the plasma concentration of the substance decreased to approximately 10% within 2 h owing to a rapid rate of distribution. A two compartment model adequately described the kinetics of midazolam in plasma. The following average values were found: elimination half-life, 2.3 h; total clearance, 323 ml/min, and apparent volume of distribution at steady-state (VSS), 50.21. After oral administration, the drug is rapidly absorbed. Maximum plasma levels are reached within 30 min and the drug is rapidly eliminated from plasma with practically the same half-life as determined after i.v. administration. The bioavailability after the ingestion of 10, 20 and 40 mg midazolam in the form of tablets ranged from 31 to 72%, due to the high liver extraction quota of midazolam.
Investigation of chiral recognition by molecular micelles with molecular dynamics simulations (2017)

Molecular dynamics simulations were used to characterize the binding of the chiral drugs chlorthalidone and lorazepam to the molecular micelle poly-(sodium undecyl-(L)-leucine-valine). The project’s goal was to characterize the nature of chiral recognition in capillary electrophoresis separations that use molecular micelles as the chiral selector. The shapes and charge distributions of the chiral molecules investigated, their orientations within the molecular micelle chiral binding pockets, and the formation of stereoselective intermolecular hydrogen bonds with the molecular micelle were all found to play key roles in determining where and how lorazepam and chlorthalidone enantiomers interacted with the molecular micelle.
Lio-A Personal Robot Assistant for Human-Robot Interaction and Care Applications (2020)

Lio is a mobile robot platform with a multi-functional arm explicitly designed for human-robot interaction and personal care assistant tasks. The robot has already been deployed in several health care facilities, where it is functioning autonomously, assisting staff and patients on an everyday basis. Lio is intrinsically safe by having full coverage in soft artificial-leather material as well as collision detection, limited speed and forces. Furthermore, the robot has a compliant motion controller. A combination of visual, audio, laser, ultrasound and mechanical sensors are used for safe navigation and environment understanding. The ROS-enabled setup allows researchers to access raw sensor data as well as have direct control of the robot. The friendly appearance of Lio has resulted in the robot being well accepted by health care staff and patients. Fully autonomous operation is made possible by a flexible decision engine, autonomous navigation and automatic recharging. Combined with time-scheduled task triggers, this allows Lio to operate throughout the day, with a battery life of up to 8 hours and recharging during idle times. A combination of powerful computing units provides enough processing power to deploy artificial intelligence and deep learning-based solutions on-board the robot without the need to send any sensitive data to cloud services, guaranteeing compliance with privacy requirements. During the COVID-19 pandemic, Lio was rapidly adjusted to perform additional functionality like disinfection and remote elevated body temperature detection. It complies with ISO13482 - Safety requirements for personal care robots, meaning it can be directly tested and deployed in care facilities.
HPV Infection in Men (2007)

While much is known about the natural history of cervical human papillomavirus (HPV) infection and its consequences, including cervical intraepithelial neoplasia and cervical cancer, relatively little is known about the natural history of anogenital HPV infection and diseases in men. In part this reflects difficulties in penile sampling and visual assessment of penile lesions. Anal HPV infection and disease also remain poorly understood. Although HPV is transmitted sexually and infects the genitals of both sexes, the cervix remains biologically more vulnerable to malignant transformation than does the penis or anus in men. An understanding of male HPV infection is therefore important in terms of reducing transmission of HPV to women and improving women's health. However, it is also important due to the burden of disease in men, who may develop both penile and anal cancer, particularly among HIV-positive men who have sex with men. Improved sampling techniques of the male genitalia and cohort studies in progress should provide important information on the natural history of anogenital HPV infection and disease in men, including risk factors for HPV acquisition and transmission. The impact of HPV vaccination in women on male anogenital HPV infection will also need to be assessed.
Effect of Al<sub>2</sub>Ca on Oxidation Resistance and Tensile Property of Al-5Mg Alloy (2014)

The effect of <TEX>$Al_2Ca$</TEX> on the oxidation resistance and tensile property of Al-5Mg alloys was investigated. According to the TGA (Thermogravimetric analysis) result at <TEX>$550^{\circ}C$</TEX> after 24hrs, the Al-5Mg alloy showed parabolic behavior with weight gain. On the other hand, there was almost no difference in the weight changes of the <TEX>$Al_2Ca$</TEX> added Al-5Mg alloys during the oxidation. It was thought that the improvement of oxidation resistance in <TEX>$Al_2Ca$</TEX> added Al-5Mg alloys might be due to the formation of a protective oxide layer with CaO and MgO on the surface. The microstructures of the alloys showed grain refinement with an increasing <TEX>$Al_2Ca$</TEX> content. From the tensile test, the yield strength of the alloys were improved with an increasing <TEX>$Al_2Ca$</TEX> content. The 0.07 mass%<TEX>$Al_2Ca$</TEX> added Al-5Mg alloy showed similar elongation and increased strength, simultaneously. It was considered that the addition of <TEX>$Al_2Ca$</TEX>, which was superior in the oxidation resistance of Al, reduced the formation of Mg oxides and inclusions during the alloying. This, partly led to the improvement of tensile properties.
Usefulness of Exercise for Home Blood Pressure Control in People with Diabetes: A Study Protocol for a Crossover Randomized Controlled Trial [Corrigendum] (2022)

[This corrects the article DOI: 10.2147/DMSO.S280117.].