gebhart/patrepeval huggingface dataset:
Emergent technologies: 25 years (2013)

This paper will talk about the technologies that have been emerging over the 25 years since the Human Vision and Electronic Imaging conference began that the conference has been a part of, and that have been a part of the conference, and will look at those technologies that are emerging today, such as social networks, haptic technologies, and still emerging imaging technologies, and what we might look at for the future.Twenty-five years is a long time, and it is not without difficulty that we remember what was emerging in the late 1980s. Yet to be developed: The first commercial digital still camera was not yet on the market, although there were hand held electronic cameras. Personal computers were not displaying standardized images, and image quality was not something that could be talked about in a standardized fashion, if only because image compression algorithms were not standardized yet for several years hence. Even further away were any standards for movie compression standards, there was no personal computer even on the horizon which could display them. What became an emergent technology and filled many sessions later, image comparison and search, was not possible, nor the current emerging technology of social networks- the world wide web was still several years away. Printer technology was still devising dithers and image size manipulations which would consume many years, as would scanning technology, and image quality for both was a major issue for dithers and Fourier noise.From these humble beginnings to the current moves that are changing computing and the meaning of both electronic devices and human interaction with them, we will see a course through the changing technology that holds some features constant for many years, while others come and go.
New cinnamic acid esters from Ocimum basilicum (2007)

Studies on the chemical constituents of the aerial parts of Ocimum basilicum have led to the isolation of a new ferulate, 4'-carbomethoxy-2'-hydroxy phenyl ferulate (1) and a new cinnamate, (E)-3'-hydroxy-4'-(1''-hydroxyethyl)-phenyl-4-methoxycinnamate (2). Their structures have been elucidated through spectral studies including 2D-NMR experiments (HMQC, HMBC, COSY-45 degrees , NOESY and 2D-J resolved).
Analysis of offsite Emergency Planning Zones (EPZ) for the Rocky Flats Plant (1990)

This project plan for Phase II summarizes the design of a project to complete analysis of offsite Emergency Planning Zones (EPZ) for the Rocky Flats Plant. Federal, state, and local governments develop emergency plans for facilities that may affect the public in the event of an accidental release of nuclear or hazardous materials. One of the purposes of these plans is to identify EPZs where actions might be necessary to protect public health. Public protective actions include sheltering, evacuation, and relocation. Agencies use EPZs to develop response plans and to determine needed resources. The State of Colorado, with support from the US Department of Energy (DOE) and Rocky Flats contractors, has developed emergency plans and EPZs for the Rocky Flats Plant periodically beginning in 1980. In Phase II, Interim Emergency Planning Zones Analysis, Maximum Credible Accident'' we will utilize the current Rocky Flats maximum credible accident (MCA), existing dispersion methodologies, and upgraded dosimetry methodologies to update the radiological EPZs. Additionally, we will develop recommendations for EPZs for nonradiological hazardous materials releases and evaluate potential surface water releases from the facility. This project will allow EG G Rocky Flats to meet current commitments to the state of Colorado and make steady, tangible improvements in our understanding of risk to offsite populations during potential emergencies at the Rocky Flats Plant. 8 refs., 5 figs., 4 tabs.
The Presence of Calcitonin Gene-Related Peptide and Its Receptors in Rat, Pig and Human Brain: Species Differences in Calcitonin Gene-Related Peptide Pharmacology (2019)

Cerebellum and cerebral cortex are rich in CGRP and CGRP receptors, which can be antagonized by gepants. However, all gepants display higher affinity for human CGRP receptors as compared to rat and pig CGRP receptors. Furthermore, human cerebellum seems to express higher density of CGRP receptors.
ChemInform Abstract: Transition Metal‐Free Direct Trifluoromethylation of 2,3‐Dihydropyridin‐4(1H)‐ones at Room Temperature. (2015)

Abstract A radical mechanism is assumed to occur.
PUMA: A Programmable Ultra-efficient Memristor-based Accelerator for Machine Learning Inference (2019)

Memristor crossbars are circuits capable of performing analog matrix-vector multiplications, overcoming the fundamental energy efficiency limitations of digital logic. They have been shown to be effective in special-purpose accelerators for a limited set of neural network applications. We present the Programmable Ultra-efficient Memristor-based Accelerator (PUMA) which enhances memristor crossbars with general purpose execution units to enable the acceleration of a wide variety of Machine Learning (ML) inference workloads. PUMA's microarchitecture techniques exposed through a specialized Instruction Set Architecture (ISA) retain the efficiency of in-memory computing and analog circuitry, without compromising programmability. We also present the PUMA compiler which translates high-level code to PUMA ISA. The compiler partitions the computational graph and optimizes instruction scheduling and register allocation to generate code for large and complex workloads to run on thousands of spatial cores. We have developed a detailed architecture simulator that incorporates the functionality, timing, and power models of PUMA's components to evaluate performance and energy consumption. A PUMA accelerator running at 1 GHz can reach area and power efficiency of $577~GOPS/s/mm^2$ and $837~GOPS/s/W$, respectively. Our evaluation of diverse ML applications from image recognition, machine translation, and language modelling (5M-800M synapses) shows that PUMA achieves up to $2,446\times$ energy and $66\times$ latency improvement for inference compared to state-of-the-art GPUs. Compared to an application-specific memristor-based accelerator, PUMA incurs small energy overheads at similar inference latency and added programmability.
Monoamine release from cat spinal cord by somatic stimuli: an intrinsic modulatory system. (1981)

1. Superfusates taken from spinal cords of cats anaesthetized with chloralose and urethane were assayed for endogenous serotonin and noradrenaline by high-pressure liquid chromatography with electrochemical detection. 2. Stimulating the dorsolateral funiculus, caudal to a spinal transection, enhanced in a frequency-dependent manner the levels of monoamines in the spinal superfusate. 3. Tyramine added to the superfusate enhanced the release of noradrenaline and serotonin. 4. In cats with intact neuraxes, stimulation of the sciatic nerve at high, but not low intensities produced a 2- to 3-fold increase in the levels of monoamines in the spinal superfusate. This evoked monoamine efflux was attenuated by cold block of the cervical spinal cord. 5. Stimulation of the infraorbital branch of the trigeminal nerve evoked the release of noradrenaline and serotonin from the lumbar cord in animals with intact neuraxes. Cold block of the cervical cord blocked trigeminal-evoked release of lumbar serotonin and noradrenaline. 6. That the monoamine efflux was not due to elevations in blood pressure was indicated by the failure of vasoxyl, an alpha-agonist producing hypertension, to evoke any changes in spinal monoamine levels. 7. The monoamine release was not dependent upon either an opiate-sensitive link or upon the activation of the sympathetic ganglia, because systemic administration of naloxone (an opiate antagonist) and chlorisondamine (a ganglionic blocking agent) failed to antagonize the evoked release of amines. 8. These results suggest the existence of a spinopetal monoamine system which is activated by peripheral stimuli. The modulatory influence associated with increasing monoamine tone in the spinal cord clearly indicated that somatic stimuli may activate a descending monoamine pathway which serves to modulate the magnitude of the ascending sensory message.
A high-swing CMOS telescopic operational amplifier (1998)

A high-swing, high-performance CMOS telescopic operational amplifier is described. The high swing of the op-amp is achieved by employing the tail and current source transistors in the deep linear region. The resulting degradation in differential gain, common-mode rejection ratio (CMRR), and other amplifier characteristics are compensated by applying regulated-cascode differential gain enhancement and a replica-tail feedback technique. A prototype of the op-amp has been built in a 0.81-/spl mu/m CMOS process. Operating from a power supply of 3.3 V, it achieves a differential swing of /spl plusmn/2.15 V, a differential gain of 90 dB, unity-gain frequency of 90 MHz, and >50-dB CMRR. It is shown, analytically and through simulations, that the operational amplifier maintains its high CMRR even at high frequencies.
Novel Quinolylnitrones Combining Neuroprotective and Antioxidant Properties (2019)

We describe here the preparation, neuroprotective analysis, and antioxidant capacity of 11 novel quinolylnitrones (QN). The neuroprotective analysis of QN1-11 in an oxygen-glucose deprivation model, in primary neuronal cultures, has been determined, allowing us to identify QN6 as a very potent neuroprotective agent, showing significant high value at 0.5 and 10 μM (86.2%), a result in good agreement with the observed strong hydroxyl radical scavenger of QN6.
Urine—Waste or Resource? The Economic and Social Aspects (2013)

The diminishing fossil fuel resources as well as the alarming state of the planet's climate are sensitising the world community for a better, global environment. The need for new, universal and carbon-neutral renewable fuel is pushing the number of research fields into finding alternative fuel sources or exploring new technologies. The Microbial Fuel Cell (MFC) represents one of the most promising opportunities where the direct extraction of electricity from a variety of organic waste products comes with the added benefit of cleaner waste. MFCs have the potential to reinvent energy production from organic waste and detritus sediments that are abundant and widely available around the planet. More recently, urine has been added to the list of fuel sources that MFCs can directly utilise for the production of renewable energy, which is a process that can also result in the recycling of elements, such as nitrogen, phosphorous and potassium, naturally found in urine.
Safety and Outcomes of a Plasmid DNA Vaccine Encoding the ERBB2 Intracellular Domain in Patients With Advanced-Stage ERBB2-Positive Breast Cancer (2022)

ClinicalTrials.gov Identifier: NCT00436254.
Functional Analysis of the Cell Division Protein FtsW of Escherichia coli (2004)

Site-directed mutagenesis experiments combined with fluorescence microscopy shed light on the role of Escherichia coli FtsW, a membrane protein belonging to the SEDS family that is involved in peptidoglycan assembly during cell elongation, division, and sporulation. This essential cell division protein has 10 transmembrane segments (TMSs). It is a late recruit to the division site and is required for subsequent recruitment of penicillin-binding protein 3 (PBP3) catalyzing peptide cross-linking. The results allow identification of several domains of the protein with distinct functions. The localization of PBP3 to the septum was found to be dependent on the periplasmic loop located between TMSs 9 and 10. The E240-A249 amphiphilic peptide in the periplasmic loop between TMSs 7 and 8 appears to be a key element in the functioning of FtsW in the septal peptidoglycan assembly machineries. The intracellular loop (containing the R166-F178 amphiphilic peptide) between TMSs 4 and 5 and Gly 311 in TMS 8 are important components of the amino acid sequence-folding information.
Advanced constructional play with LEGOs among preschoolers as a predictor of later school achievement in mathematics (2003)

The research question asked was “Will those children ages three and four who have intensive play experiences in play‐based preschools and who can perform at high levels of LEGO building as constructional play also show high levels of mathematical achievement later in formal school settings?”. Thus, this study attempts to establish a correlation between the levels of LEGO play performance of young children and their later school (elementary, middle, and high school) achievement in mathematics. The predictor variables of levels of LEGO play, while controlling for IQ, and gender, were measured in Fall 1982 by testing a group of 3‐year‐old and 4‐year‐old preschoolers (n = 47), and later, longitudinal effects were examined after these same participants had completed high school (n = 37). The dependent or outcome variables obtained from the participants' school cumulative records included: (1) results from the California Achievement Test, (2) the grades in mathematics courses, and (3) higher mathematics courses taken in high school. LEGO performance during the preschool years and the later variables of students' letter grades, and mathematical achievement on standardized tests did not demonstrate significance at the third and fifth grade levels. At the same time no significance was found at seventh grade levels on teacher‐awarded grades, but a clear significance was found for standardized testing at the seventh grade level. Also, since all other outcome variables at the middle school and high school levels such as number of mathematics classes taken, number of honors mathematics classes taken, average mathematics grades, and a combined weighted value of all mathematics courses taken were all significant, we may clearly state that there is a statistical relationship between early LEGO performance among preschool and achievement in mathematics, not seen during the elementary school years, but later developing at the middle and high school level.
Modeling a 3-D non-rigid virtual object by motion capture and its appearance in the real space (2003)

A technique is described for creating a 3-D non-rigid virtual object and projecting it into real space. Real human walking motion is reconstructed employing a developed motion capture system and the obtained 3-D human model is projected into a real space through a see-through type head mounted display. The realized environment is referred to as a mixed reality space. The developed system not only provides smooth motion of the virtual human, but also solves the occlusion problem among the real objects in front of the observer and the projected virtual human. The performed experiment gives satisfactory results.
Algunas consideraciones acerca del problema de la longevidad en Cuba (1986)

Une revue est faite de la litterature et les principaux criteres existant actuellement au niveau mondial par rapport a cette importante question sont signales et particulairises en divers documents cubains qui synthetisent les experiences et les perspectives en ce qui concerne la conduite a tenir avec les sujets tres âges
Enthalpies of mixtures of polar and nonpolar component. System n-pentanol-n-heptane (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEnthalpies of mixtures of polar and nonpolar component. System n-pentanol-n-heptaneTran P. Thinh, Rubens S. Ramalho, and Serge C. KaliaguineCite this: J. Chem. Eng. Data 1975, 20, 1, 61–65Publication Date (Print):January 1, 1975Publication History Published online1 May 2002Published inissue 1 January 1975https://pubs.acs.org/doi/10.1021/je60064a030https://doi.org/10.1021/je60064a030research-articleACS PublicationsRequest reuse permissionsArticle Views59Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Hesseltin A, a Novel Antiviral Metabolite from Penicillium hesseltinei. (2005)

Hesseltin A (&lt;b&gt;1&lt;/b&gt;), a novel compound of mixed polyketide-terpenoid origins was isolated from the filamentous fungus &lt;i&gt;Penicillium &lt;/i&gt;&lt;i&gt;hesseltinei&lt;/i&gt;. The\nstructure and stereochemistry were determined from extensive one- and two-dimensional NMR and mass spectral data.
Lactobacillus hordniae, a New Species from the Leafhopper (Hordnia circellata) (1977)

A gram-positive, rod-shaped bacterium, originally thought by Auger (1974) to be the agent of Pierce&apos;s disease of grapevines, is commonly associated with Hordnia circellata, one of the leafhopper vectors of the disease. The bacterium has the following colonial and cellular characteristics: smooth, glistening white, or chalky colonies, 0.4 to 0.5 mm in diameter with entire margins; gram positive becoming gram variable after 5 days in culture; nonmotile and nonsporeforming; grows between 15 and 37°C with an optimum between 28 and 30°C and no growth at 9 or 45°C; optimum growth occurs at pH 6.5, with growth observed at pH 4.5 and pH 9.0. The bacterium does not survive after 5 to 7 days of growth and must be maintained on fresh medium. It is rod-shaped (0.6 by 1.5 to 2.0 μm), growing in short chains of three to four cells each, and possesses mesosomes and a cell wall of uniform thickness (28 to 35 nm) that consists of an electrondense outer layer and an inner layer resembling unit-membrane structure. The organism is a facultative anaerobe which reacts negatively in tests for cytochrome oxidase, catalase, “gelatinase,” urease, tryptophanase, and nitrate and disulfide reductase activities. No dextran or levan is produced from sucrose. It produces L-(+)-lactic acid but not D-(—)-lactic acid from glucose and sucrose fermentation, acetylmethylcarbinol, or arginine deaminase. Glucose, sucrose, galactose, maltose, fructose, trehalose, salicin, inulin, and cellobiose, but not gluconate, lactose, mannose, mannitol, sorbitol, melibiose, or raffinose, were utilized as carbon sources. Its chromosome has an average guanine-plus-cytosine content of 32.75 mol%. Based on these features, the bacterium appears to be a hitherto unrecognized species of the genus Lactobacillus, for which the name Lactobacillus hordniae sp. nov. is proposed. The type strain is HC-1 (= ATCC 29071).
Distortion Simulation of Unsymmetrical Composite Laminates Using the Finite Element Analysis Method (2007)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
Ketamine: differential neurophysiological dynamics in functional networks in the rat brain (2017)

Recently, the N-methyl-d-aspartate-receptor (NMDAR) antagonist ketamine has emerged as a fast-onset mechanism to achieve antidepressant activity, whereas its psychomimetic, dissociative and amnestic effects have been well documented to pharmacologically model schizophrenia features in rodents. Sleep-wake architecture, neuronal oscillations and network connectivity are key mechanisms supporting brain plasticity and cognition, which are disrupted in mood disorders such as depression and schizophrenia. In rats, we investigated the dynamic effects of acute and chronic subcutaneous administration of ketamine (2.5, 5 and 10 mg kg<sup>-1</sup>) on sleep-wake cycle, multichannels network interactions assessed by coherence and phase-amplitude cross-frequency coupling, locomotor activity (LMA), cognitive information processing as reflected by the mismatch negativity-like (MMN) component of event-related brain potentials (ERPs). Acute ketamine elicited a short, lasting inhibition of rapid eye movement (REM) sleep, increased coherence in higher gamma frequency oscillations independent of LMA, altered theta-gamma phase-amplitude coupling, increased MMN peak-amplitude response and evoked higher gamma oscillations. In contrast, chronic ketamine reduced large-scale communication among cortical regions by decreasing oscillations and coherent activity in the gamma frequency range, shifted networks activity towards slow alpha rhythm, decreased MMN peak response and enhanced aberrant higher gamma neuronal network oscillations. Altogether, our data show that acute and chronic ketamine elicited differential changes in network connectivity, ERPs and event-related oscillations (EROs), supporting possible underlying alterations in NMDAR-GABAergic signaling. The findings underscore the relevance of intermittent dosing of ketamine to accurately maintain the functional integrity of neuronal networks for long-term plastic changes and therapeutic effect.
SUPPRESSOR CELLS IN RHESUS MONKEYS TREATED WITH ANTITHYMOCYTE GLOBULIN (1982)

Treatment of rhesus monkey skin allograft recipients with a brief course of rabbit antithymocyte globulin (ATG) produces an enduring immunosuppressive effect on the cellular immune system. Despite early recovery of circulating T cells, in vitro mitogen-induced lymphoproliferative responses of peripheral blood mononuclear cells (PBMCs) remain abnormally depressed for months. In this study we show that depressed mitogen-induced lymphoproliferative responses in these animals are attributable to regulatory effects of adherent PBMCs. Removal of the adherent fraction of PBMCs on Sephadex G-10 produced a significant restoration of the mitogen-induced lymphoproliferative responses in ATG-treated monkeys. Addition of the prostaglandin synthetase inhibitor indomethacin to cultures of unfractionated PBMCs from these animals also caused a significant recovery of the lymphoproliferative response. Indomethacin did not enhance the response of control animals or the response of the nonadherent PBMC fraction of ATG-treated animals. These data suggest that a prostaglandin-dependent mechanism is involved in the suppressive action of the adherent cells. PBMCs from ATG-treated monkeys cocultured with normal cryopreserved autologous cells induced a dose-dependent suppression in the response to both concanavalin A (Con A) and phytohemagglutinin (PHA). The suppressive activity depended upon the adherent cell fraction and was found to be resistant to low-dose gamma irradiation. These data indicate that administration of rabbit ATG induces nonspecific suppressor cells in the rhesus monkey. Preliminary characterization studies suggest the involvement of suppressor monocytes. The possible role of this suppressor cell system in the immunosuppressive action of rabbit ATG is discussed.
Emollients and the response of facial skin to a cold environment (2003)

This study demonstrates that for a duration exposure of 20 min, facial skin treated with O/W achieves a lower temperature than facial skin treated with petrolatum. The two emollients had in all other aspects the same effect on the response of facial skin to cold.