gebhart/patrepeval huggingface dataset:
Heterogeneous Computational Resource Allocation for C-RAN: A Contract-Theoretic Approach (2019)

In this work, we develop a contract theory framework to tackle the allocations of heterogeneous baseband processing units (BBUs) in cloud radio access network. We first model a monopoly market by viewing the BBUs as a kind of resource. The infrastructure provider (InP), as the monopolist, owns all the heterogeneous BBUs of different processing abilities and maintaining costs, and leases them to multiple mobile network operators (MNOs) to gain profit. At the same time, the MNOs intend to rent reasonable amount of BBUs to provide services to their mobile clients. Then we propose a contract theory framework, in which contract items are optimized to maximize the InP’s utility, while maintain the welfare of the MNOs. We design the optimal contracts with complete and asymmetric information on the MNOs. Our contract design achieves the near optimum solution to heterogeneous computational resource allocation even under the information asymmetric case. Our derivations indicate that the optimal contracts with asymmetric information achieve a lower utility for the InP than the ones with complete information and the utility reduction is higher when the BBUs are heterogeneous rather than homogeneous. Numerical results demonstrate that, the InP having heterogeneous BBUs can achieve a higher utility relative to having homogeneous BBUs, which is more profitable and realistic for the InP. Moreover, we regard Stackelberg game theoretic approach as a comparison, and show that our method is more realistic.
Diagnosis and management ofPneumocystis jiroveciiinfection (2017)

Pneumocystis jirovecii is a ubiquitous fungus, which causes pneumonia in humans. Diagnosis was hampered by the inability to culture the organism, and based on microscopic examination of respiratory samples or clinical presentation. New assays can assist in the diagnosis and even aid with the emergence of resistant infections. Areas covered: This manuscript will provide background information on Pneumocystis pneumonia (PcP). Diagnosis, from radiological to non-microbiological (e.g. Lactate dehydrogenase) and microbiological investigations (Microscopy, PCR, β-D-Glucan) will be discussed. Recommendations on prophylactic and therapeutic management will be covered. Expert commentary: PcP diagnosis using microscopy is far from optimal and false negatives will occur. With an incidence of 1% or less, the pre-test probability of not having PcP is 99% and testing is suited to excluding disease. Microscopy provides a high degree of diagnostic confidence but it is not infallible, and its lower sensitivity limits its application. Newer diagnostics (PCR, β-D-Glucan) can aid management and improve performance when testing less invasive specimens, such as upper respiratory samples or blood, alleviating clinical pressure. Combination testing may allow PcP to be both diagnosed and excluded, and molecular testing can assist in the detection of emerging resistant PcP.
Methods of measuring the nonlinear-optical coefficients of the refractive index of nonlinear media (2006)

A cousistent analysis of a method of measuring the coefficient n 2 of the Kerr nonlinearity and the two-photon absorption coefficient in presented. The method is based on the study of the dependence of the nonlinear transmittance with respect to the far-field axial intensity of the laser beam on the position of the layer of the nonlinear medium on the z (longitudinal) coordinate of this beam (z scanning). The possibility for the measurement of n 2 and the two-photon (multiphoton) absorption coefficient based on the study of the far-field variations in the spatial profile of the beam having passed through the nonlinear medium is also analyzed. The calculations prove the efficiency of the new method for measuring n 2 and the two-photon (multiphoton) absorption coefficient.
Pharmacokinetic profile and behavioral effects of gabapentin in the horse (2010)

Gabapentin is being used in horses although its pharmacokinetic (PK) profile, pharmacodynamic (PD) effects and safety in the equine are not fully investigated. Therefore, we characterized PKs and cardiovascular and behavioral effects of gabapentin in horses. Gabapentin (20 mg/kg) was administered i.v. or p.o. to six horses using a randomized crossover design. Plasma gabapentin concentrations were measured in samples collected 0-48 h postadministration employing liquid chromatography-tandem mass spectrometry. Blood pressures, ECG, and sedation scores were recorded before and for 12 h after gabapentin dosage. Nineteen quantitative measures of behaviors were evaluated. After i.v. gabapentin, the decline in plasma drug concentration over time was best described by a 3-compartment mammillary model. Terminal elimination half-life (t(1/2γ) ) was 8.5 (7.1-13.3) h. After p.o. gabapentin terminal elimination half-life () was 7.7 (6.7-11.9) h. The mean oral bioavailability of gabapentin (± SD) was 16.2 ± 2.8% indicating relatively poor absorption of gabapentin following oral administration in horses. Gabapentin caused a significant increase in sedation scores for 1 h after i.v. dose only (P < 0.05). Among behaviors, drinking frequency was greater and standing rest duration was lower with i.v. gabapentin (P < 0.05). Horses tolerated both i.v. and p.o. gabapentin doses well. There were no significant differences in and . Oral administration yielded much lower plasma concentrations because of low bioavailability.
Abstract B163: Over-expression of STAT-3 induces anoikis resistance, promotes cell migration and metastatic potential in cancer cells. (2013)

Abstract Anoikis is an anchorage independent cell death. Resistance to anoikis is one of the key features of the metastatic cells. In the current study, we have shown the role of STAT-3 in anoikis resistance in various melanoma and pancreatic cancer cells. Marked anoikis was induced as such in the cells that were grown in anchorage-independent conditions. The melanoma and pancreatic cancer cells that resisted anoikis were observed to have higher rate of migration as compared to the cells that were exposed to anchorage dependent growth, as observed in cell migration and invasion assays. These anoikis resistant cells also had significantly higher expression and phosphorylation of STAT-3 at Tyr 705, than the cells that were attached to the basement membrane. Treatment of these cells with IL-6, a cytokine which phosphorylates STAT-3, prevented the induction of anoikis. STAT-3 inhibitors AG490 and piplartine induced anoikis in a concentration-dependent manner, whereas IL-6 blocked anoikis. Over-expression of STAT-3 by transfection, not only increased the anoikis resistance but also protected cancer cells from piplartine-induced anoikis, confirming the role of STAT-3 in anoikis resistance. On the other hand, silencing STAT-3 decreased the potential of cancer cells to resist anoikis. Furthermore, STAT-3 (-/-) cancer cells were more sensitive to anoikis as well as to the effect of piplartine as compared to STAT-3 (+/+) cells. The STAT-3 (+/+) cells also had enhanced migration potential as compared to STAT-3 (-/-) cells. STAT-3 (-/-) cells and the cells that were treated with PL completely failed to develop tumors when injected subcutaneously in immune-compromised mice. Moreover, these cells also failed to metastasize when injected intravenously. On the other hand, STAT-3 (+/+) cells not only formed aggressive tumors subcutaneously but also highly metastasized when injected intravenously. In summary, our results establish STAT-3 as a critical player that renders anoikis resistance to the cancer cells and enhance their metastasis potential. Citation Information: Mol Cancer Ther 2013;12(11 Suppl):B163. Citation Format: Neel Manoj Fofaria, Sanjay K. Srivastava. Over-expression of STAT-3 induces anoikis resistance, promotes cell migration and metastatic potential in cancer cells. [abstract]. In: Proceedings of the AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; 2013 Oct 19-23; Boston, MA. Philadelphia (PA): AACR; Mol Cancer Ther 2013;12(11 Suppl):Abstract nr B163.
Magnesium acceptor in gallium nitride. I. Photoluminescence from Mg-doped GaN (2018)

Defect-related photoluminescence (PL) is analyzed in detail for $n$-type, $p$-type, and semi-insulating Mg-doped GaN grown by different techniques. The ultraviolet luminescence (UVL) band is the dominant PL band in conductive $n$-type and $p$-type GaN:Mg samples grown by hydride vapor phase epitaxy (HVPE) and molecular beam epitaxy. The UVL band in undoped and Mg-doped GaN samples is attributed to the shallow $\mathrm{M}{\mathrm{g}}_{\mathrm{Ga}}$ acceptor with the ionization energy of 223 meV. In semi-insulating GaN:Mg samples, very large shifts of the UVL band (up to 0.6 eV) are observed with variation of temperature or excitation intensity. The shifts are attributed to diagonal transitions, likely due to potential fluctuations or near-surface band bending. The blue luminescence $(\mathrm{B}{\mathrm{L}}_{\mathrm{Mg}})$ band is observed only in GaN:Mg samples grown by HVPE or metalorganic chemical vapor deposition when the concentration of Mg exceeds ${10}^{19}\phantom{\rule{0.16em}{0ex}}\mathrm{c}{\mathrm{m}}^{\ensuremath{-}3}$. The $\mathrm{B}{\mathrm{L}}_{\mathrm{Mg}}$ band is attributed to electron transitions from an unknown deep donor to the shallow $\mathrm{M}{\mathrm{g}}_{\mathrm{Ga}}$ acceptor. Basic properties of the observed PL are explained with a phenomenological model.
Self‐Assembly of One‐ and Two‐Dimensional Hemoprotein Systems by Polymerization through Heme–Heme Pocket Interactions (2008)

Abstract Supramolekulare Proteinpolymere : Wenn eine Hämeinheit an der Oberfläche einer Apo‐Cytochrom‐b 562 (H63C)‐Mutante eingeführt wird, entstehen durch nichtkovalente Wechselwirkungen zwischen Hämtaschen supramolekulare Polymere. Der Einbau einer Hämtriade als Angelmolekül in das Proteinpolymer führt zu einer zweidimensionalen Proteinnetzwerkstruktur, die mithilfe der Rasterkraftmikroskopie im intermittierenden Modus sichtbar gemacht wurde (siehe Bild). magnified image
A sandwich ELISA for measurement of the primary glucagon-like peptide-1 metabolite (2017)

Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from the gastrointestinal tract. It is best known for its glucose-dependent insulinotropic effects. GLP-1 is secreted in its intact (active) form (7-36NH<sub>2</sub>) but is rapidly degraded by the dipeptidyl peptidase 4 (DPP-4) enzyme, converting >90% to the primary metabolite (9-36NH<sub>2</sub>) before reaching the targets via the circulation. Although originally thought to be inactive or antagonistic, GLP-1 9-36NH<sub>2</sub> may have independent actions, and it is therefore relevant to be able to measure it. Because reliable assays were not available, we developed a sandwich ELISA recognizing both GLP-1 9-36NH<sub>2</sub> and nonamidated GLP-1 9-37. The ELISA was validated using analytical assay validation guidelines and by comparing it to a subtraction-based method, hitherto employed for estimation of GLP-1 9-36NH<sub>2</sub> Its accuracy was evaluated from measurements of plasma obtained during intravenous infusions (1.5 pmol × kg<sup>-1</sup> × min<sup>-1</sup>) of GLP-1 7-36NH<sub>2</sub> in healthy subjects and patients with type 2 diabetes. Plasma levels of the endogenous GLP-1 metabolite increased during a meal challenge in patients with type 2 diabetes, and treatment with a DPP-4 inhibitor fully blocked its formation. Accurate measurements of the GLP-1 metabolite may contribute to understanding its physiology and role of GLP-1 in diabetes.
Automatic aesthetic image enhancement for consumer digital photographs (2007)

A Doctoral Thesis. Submitted in partial fulfilment of the requirements for the award of Doctor of Philosophy at Loughborough University.
Development of a Method for Markerless Gene Deletion in Pseudomonas putida (2011)

We developed a negative counterselection system for Pseudomonas putida based on uracil phosphoribosyltransferase (UPRTase) and sensitivity against the antimetabolite 5-fluorouracil (5-FU). We constructed a P. putida strain that is resistant to 5-FU and constructed vectors for the deletion of the surface adhesion protein gene, the flagellum biosynthesis operon, and two endonuclease genes. The genes were efficiently disrupted and left a markerless chromosomal in-frame deletion.
Foundations of Control and Estimation Over Lossy Networks (2007)

<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> This paper considers control and estimation problems where the sensor signals and the actuator signals are transmitted to various subsystems over a network. In contrast to traditional control and estimation problems, here the observation and control packets may be lost or delayed. The unreliability of the underlying communication network is modeled stochastically by assigning probabilities to the successful transmission of packets. This requires a novel theory which generalizes classical control/estimation paradigms. The paper offers the foundations of such a novel theory. </para>
P79-S Multiplex Detection of Non-Phosphorylated and Ser 9–Phosphorylated GSK3β Isoforms Using 2D Gel Electrophoresis and a Fluorescent-Based Western Blotting System. (2007)

Western blotting systems are most commonly used after separation of proteins on one-dimensional (1D) SDS-PAGE gels. The fluorescent-based ECL Plex Western Blotting Detection System (GE Healthcare, Piscataway, NJ) provides sensitivity, linearity, and a dynamic range of nearly four orders of magnitude, as well as the possibility of multiplex analysis-detection of two protein epitopes on the same membrane simultaneously. Multiplexing is commonly used for quantitation of one protein relative to a protein of known abundance (housekeeping protein). It can also be used for the detection and quantitation of post-translational modifications such as phosphorylation, provided that there are antibodies available. In this study, a two-dimensional Western blotting approach was evaluated in addition to the traditional 1D workflow, using fluorescent secondary antibodies, namely the ECL Plex Western Blotting Detection System. Human PC-3U cell lysate was separated by 1D and 2D SDS-PAGE, followed by blotting and incubation with primary antibodies against non-phosphorylated and Ser 9-phosphorylated forms of glycogen synthase kinase-3 beta (GSK3β). ECL Plex CyDye Cy3- and Cy5-conjugated secondary antibodies were used for simultaneous detection of the non-phosphorylated and phosphorylated forms of GSK3β. The 1D Western blotting experiment showed that both the non-phosphorylated and phosphorylated forms of GSK3β could be detected in PC-3U cells without transforming growth factor beta (TGF-β) activation. The 2D Western blotting experiment gave information on phosphorylation states that could not be obtained by 1D Western blotting. A 48-kDa band corresponding to phosphorylated GSK3β in the 1D experiments was resolved into at least five distinct protein isoforms, two of which were phosphorylated at serine 9.
Complete Photonic Band Gaps with Nonfrustrated ABC Bottlebrush Block Polymers (2020)

Bottlebrush block polymers are a promising platform for self-assembled photonic materials, yet most work has been limited to one-dimensional photonic crystals based on the lamellar phase. Here we demonstrate with simulation that nonfrustrated ABC bottlebrush block polymers can be used to self-assemble three-dimensional photonic crystals with complete photonic band gaps. To show this, we have developed a computational approach that couples self-consistent field theory (SCFT) simulations to Maxwell's equations, thereby permitting a direct link between molecular design, self-assembly, and photonic band structures. Using this approach, we calculate the phase diagram of nonfrustrated ABC bottlebrush block polymers and identify regions where the alternating gyroid and alternating diamond phases are stable. By computing the photonic band structures of these phases, we demonstrate that complete band gaps can be found in regions of thermodynamic stability, thereby suggesting a route to realize these photonic materials experimentally. Furthermore, we demonstrate that gap size depends on volume fraction, segregation strength, and polymer architecture, and we identify a design strategy based on symmetry breaking that can achieve band gaps for lower values of refractive index contrast. Taken together, the approach presented here provides a powerful and flexible tool for predicting both the self-assembly and photonic band structures of polymeric materials.
Parental Educational Investment and Children’s Academic Risk (2006)

This study uses exogenous variation in sibling sex composition to estimate the causal effect of sibship size on boys’ probabilities of private school attendance and grade retention. Using the 1990 U.S. Census, we find that for second-born boys, increased sibship size reduces the likelihood of private school attendance by six percentage points and increases grade retention by almost one percentage point. Sibship size has no effect for first-born boys. Instrumental variable estimates are largely consistent across racial groups, although the standard errors are larger for nonwhites as they have smaller sample sizes and this renders them insignificant at traditional alpha levels.
ortho‐Selective Phenol‐Coupling Reaction by Anodic Treatment on Boron‐Doped Diamond Electrode Using Fluorinated Alcohols (2009)

Enlarged scope by fluorinated mediators: Oxyl radicals are easily formed on boron-doped diamond (BDD) electrodes and can be exploited for the ortho-selective coupling to the corresponding biphenols (see scheme). At partial conversion, a clean transformation is achieved that can be applied to electron-rich as well as fluorinated phenols.
Next Generation HVAC System for Office Buildings (2009)

The new air-conditioning control method for the energy saving of buildings is proposed. The method ismainly focused on the compatibility of energy savings and comfort. The energy saving is achieved through the optimal operation of HVAC (Heating, Ventilating and air-conditioning) system, manipulating the supplying airflow temperatures to the rooms, room temperatures and the humidity. The comfort is kept by the index (PMV: Predicted Mean Vote) that comprises temperature, humidity, radiation temperature, wind velocity and so on. In order to find the HVAC system operation conditions that satisfy the comfort and energy saving at the same time, very large-scale nonlinear programming with nonlinear constraints must be solved on real time basis. To make the programming of the system practical, the driving function loaded onto a control computer is introduced. The function is made by the spline-interpolation to achieve calculation stable and adaptation to various HVAC operation modes.
Relativistic and non-relativistic electron transport in disordered alloys I. Theory (1998)

Abstract The electrical conductivity of disordered alloys is calculated using the Korringa-Kohn-Rostoker-coherent-potential approximation alloy theory in conjunction with the local approximation to density functional theory and the Kubo-Greenwood equation. Relativistic and non-relativistic expressions for the conductivity are derived. A technique for evaluation of the Kubo-Greenwood equation for arbitrary crystal symmetry using group-theoretical methods is described. Explicit expressions for scattering and current operators at complex energies below the real axis which occur in the evaluation of the Kubo-Greenwood equation are given.
Sensor array processing based on subspace fitting (1991)

Algorithms for estimating unknown signal parameters from the measured output of a sensor array are considered in connection with the subspace fitting problem. The methods considered are the deterministic maximum likelihood method (ML), ESPRIT, and a recently proposed multidimensional signal subspace method. These methods are formulated in a subspace-fitting-based framework, which provides insight into their algebraic and asymptotic relations. It is shown that by introducing a specific weighting matrix, the multidimensional signal subspace method can achieve the same asymptotic properties as the ML method. The asymptotic distribution of the estimation error is derived for a general subspace weighting, and the weighting that provides minimum variance estimates is identified. The resulting optimal technique is termed the weighted subspace fitting (WSF) method. Numerical examples indicate that the asymptotic variance of the WSF estimates coincides with the Cramer-Rao bound. The performance improvement compared to the other techniques is found to be most prominent for highly correlated signals.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Fluctuations in membranes with reduced symmetry (1989)

We discuss the effects of in-plane ordering of amphiphilic membranes on the statistics of their shape fluctuations. Effects of flexo- and ferroelectricity as well as of several kinds of orientational order are considered. We close by a discussion of the fluctuations of a membrane immersed in an anisotropic fluid Nous discutons les effets de l'ordre local des membranes d'amphiphiles sur la statistique de leurs fluctuations de forme. Nous considerons en particulier les effets de la flexo- et ferro-electricite et de differentes especes d'ordre orientationnel. Nous discutons enfin les ondulations d'une membrane immergee dans un fluide anisotropie
NOMA-based Radio Resource Allocation for Machine Type Communications in 5G and Beyond Cellular Networks (2021)

In this paper, the minimum bandwidth resource allocation problem for non-orthogonal multiple access (NOMA) based machine to machine (M2M) communications in 5G and beyond cellular networks is investigated. In order to solve the problem fast and efficiently, a persistent resource allocation based polynomial-time algorithm considering NOMA and the periodicity of the machine type communication traffic is proposed. The algorithm consists of two phases. In first phase, M2M clusters are divided into NOMA sub-clusters using a technique that minimizes the number of NOMA sub-clusters for a set of devices. In second phase, NOMA sub-clusters are allocated to resource blocks (RB) considering their quality of service (QoS) requirements while achieving minimum bandwidth reservation. Through simulations, the performance of the proposed algorithm is presented in comparison to the previously proposed access grant time interval (AGTI) based radio resource allocation algorithms. It is illustrated that the proposed algorithm improves the spectrum-efficiency significantly.
HIFiRE-5 Boundary Layer Transition and HIFiRE-1 Shock Boundary Layer Interaction (2015)

Abstract : Several advances were made under this task during FY15, the first year of this effort. A portion of the task effort focused on HIFiRE-5. For this work, new capabilities in ground test and in flight data analysis were developed. Also, as a necessary precursor to wind tunnel tests on boundary layer transition on the leeside of a cone at angle of attack, extensive computations were undertaken to understand the zero angle of attack instability behavior. Although not directly related to the topic of boundary layer transition, final analysis of the HIFiRE-1 shock boundary layer interaction experiment was completed.
ChemInform Abstract: EXPERIMENTAL DETERMINATION OF THE RELAT (1979)

Abstract Die Thermolyse des cis bzw. trans‐Tetrahydropyridazins (I) in der Gasphase ergibt jeweils ein Gemisch der Kohlenwasserstoffe (II)‐(IV) in Gesamtausb.
High-dose (131)I-tositumomab (anti-CD20) radioimmunotherapy for non-Hodgkin's lymphoma: adjusting radiation absorbed dose to actual organ volumes. (2004)

We observed large variations in organ masses among our patients. Our treatments were planned to deliver the maximally tolerated radiation dose to the dose-limiting normal organ. This work provides a simplified method for calculating patient-specific radiation doses by adjusting for the actual organ mass and shows the value of this approach in treatment planning for RIT.