gebhart/patrepeval huggingface dataset:
Performance and reliability analysis of relevance filtering for scalable distributed interactive simulation (1997)

Achieving the real-time linkage among multiple, geographically-distant, local area networks that support distributed interactive simulation (DIS) requires tremendous bandwidth and communication resources. Today, meeting the bandwidth and communication requirements of DIS is one of the major challenges facing the design and implementation of large scale DIS training exercises. In this article, we discuss the DIS scalability problem, briefly overview the major bandwidth reduction techniques currently being investigated and implemented in contemporary DIS systems, and present a detailed analysis on the performance and reliability of relevance filtering—a promising technique to improve the scalability of distributed simulation. The idea of relevance filtering is to analyze the semantic contents of the state update messages of a simulated entity (vehicle) and transmit only the ones found to be relevant to other entities. We present our entity-based model for relevance filtering and discuss the implementation of filtering-at-transmission and filtering-at-reception. We introduce the concept of filtering reliability and present different methods to eliminate or reduce filtering errors. Methods that can ensure complete filtering reliability while providing significant bandwidth reduction are developed. Performance evaluation results of relevance filtering and of the filtering reliability methods are presented. The insight gained from our work and the challenges still facing the design of large scale DIS training exercises are discussed.
Predicting solar spectra using broadband EUV irradiance measurements (2020)

Soft x-ray and EUV radiation from the Sun is absorbed by and ionizes the atmosphere, creating both the ionosphere and thermosphere. Temporal changes in irradiance energy and spectral distribution can have drastic impacts on the ionosphere, impacting technologies such as satellite drag and radio communication. Because of this, it is necessary to estimate and predict changes in Solar EUV spectral irradiance. Ideally, this would be done by direct measurement but the high cost of solar EUV spectrographs makes this prohibitively expensive. Instead, scientists must use data driven models to predict the solar spectrum for a given irradiance measurement. In this study, we further develop the Synthetic Reference Spectral Irradiance Model (SynRef). The SynRef model, which uses broadband EUV irradiance data from EUVM at Mars, was created to mirror the SORCE XPS model which uses data from the TIMED SEE instrument and the SORCE XPS instrument at Earth. Both models superpose theoretical Active Region and Quiet Sun spectra generated by CHIANTI to match daily measured irradiance data, and output a modeled solar EUV spectrum for that day. By adjusting the weighting of Active Region and Quiet Sun spectra, we update the SynRef model to better agree with the FISM model and with spectral data collected from sounding rocket flights. We also use the broadband EUVM measurements to estimate AR temperature. This will allow us to select from a library of AR reference spectra with different temperatures. We present this updated SynRef model to more accurately characterize the Solar EUV and soft x-ray spectra.
Coordinated Vγ and Vδ gene segment rearrangements in human T cell receptor γ/δ+ lymphocytes (1989)

Monoclonal antibodies (mAb) were used to characterize a panel (n = 46) of T cell receptor (TcR) gamma/delta+ T cell clones. Three of these antibodies have been described to react with specific variable region-encoded protein products and can therefore be used to detect functional gene rearrangements. The majority of peripheral blood-derived clones (43 out of 45) expressed the epitopes recognized by mAb BB3, encoded by the V delta 2 gene segment and mAb Ti gamma A, encoded by the V gamma 9 gene segment. These clones lacked the antigenic determinant recognized by mAb delta-TCS-1, encoded by the V delta 1 gene segment. The other two peripheral blood-derived clones and an ascites-derived clone were Ti gamma A-, BB3- and delta-TCS-1+. Biochemical analysis revealed that all Ti gamma A+, BB3+ T cell clones expressed the disulfide-linked form of the receptor. The two peripheral blood-derived delta-TCS-1+ T cell clones expressed the nondisulfide-linked form whereas the ascites-derived delta-TCS-1+ clone, AK119 expressed the disulfide-linked form of the TcR gamma/delta heterodimer. This indicates that V delta 1-encoded delta chains can be associated either with a C gamma 1- or a C gamma 2-encoded gamma chain. The preferential use of certain V gamma and V delta gene segments suggests the existence of a limited combinatorial diversity in TcR gamma/delta heterodimers, i.e. Ti gamma A+ (V gamma 9), BB3+ (V delta 2) and delta-TCS-1- disulfide-linked heterodimers and Ti gamma A-, BB3- and delta-TCS-1+ (V delta 1) disulfide- or non disulfide-linked forms.
The surface diffusion of Ga on an AlGaN/GaN stripe structure in the selective MOVPE (2006)

Abstract The growth of GaN with an AlGaN/GaN heterostructure was attempted on a (111) Si substrate by selective area metal organic vapor phase epitaxy. The GaN obtained was a trapezoidal stripe with (1 $ \bar 1 $ 01) facets on the sides and a (0001) facet on the top. The distribution of the Al composition on the facets was investigated by cathodeluminescence analyses as a function of the position. The surface diffusion of Ga on the (0001) AlGaN facet was studied under various growth conditions. It was found that the diffu‐ sion length is enhanced by elevating the growth temperature or lowering the Al composition. By the temperature dependence of the diffusion length, the activation energy of the Ga species was estimated. The results depended on the Al composition x ; 1.23 ± 0.44 eV ( x = 0.05), 1.84 ± 0.58 eV ( x = 0.10) and 2.72 ± 0.73 eV ( x = 0.15). (© 2006 WILEY‐VCH Verlag GmbH &amp; Co. KGaA, Weinheim)
Use of carbon black to eliminate surface charging effects in photoelectron spectroscopy measurements of powders (1997)

The photoelectron spectra of SiO2 on silicon powder is measured with and without the addition of carbon black. Samples without carbon black show significant charging and peak deformation due to photoelectron emission. Samples containing carbon black show no evidence of charging. Furthermore, the contribution from carbon black can be subtracted from the overall signal in the valence band region to give valence band spectra of insulating powders. It is suggested that mixing carbon black with nonconducting powders may be an effective way to eliminate surface charging effects while at the same time providing a useful calibration standard.
ChemInform Abstract: Preparation and Properties of Low‐Calcium‐Content Superconductive Thin Films in Bismuth Systems. (1993)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Design Research Issues for an Interplanetary Habitat (1997)

&lt;div class="htmlview paragraph"&gt;This paper presents an “Inquiry by Design” approach to the problem of architectural design for the crew habitat of an interplanetary vehicle. This habitat must meet a range of difficult requirements to protect the crew's health and safety during the approximately 6 to 12 month voyage each way. It must provide a habitable environment that affords the crew privacy, group activities, recreation, exercise, communications, training facilities, and health care. It must incorporate countermeasures against prolonged exposure, to zero gravity and shielding against radiation from solar flares and galactic cosmic rays.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;The design research involves the investigation of a prototype interplanetary habitat that incorporates substantial radiation shielding for the crew quarters and a human powered, short-arm centrifuge for zero gravity countermeasures. It includes private crew quarters, life support system, stowage and equipment volumes. This &lt;i&gt;inquiry by design&lt;/i&gt; exercise explores the habitat components subsystem by subsystem to find the challenges that emerge for integrating them. This exercise in designing an optimized interplanetary habitat reveals some key design and engineering issues for NASA to consider in developing a Mars vehicle.&lt;/div&gt;
MPEP reduces seizure severity in Fmr-1 KO mice over expressing human Abeta. (2009)

Metabotropic glutamate receptor 5 (mGluR(5)) regulates the translation of amyloid precursor protein (APP) mRNA. Under resting conditions, mRNA is bound to and translationally repressed by the fragile X mental retardation protein (FMRP). Upon group 1 mGluR activation, FMRP dissociates from the mRNA and translation ensues. APP levels are elevated in the dendrites of primary neuronal cultures as well as in synaptoneurosomes (SN) prepared from embryonic and juvenile fmr-1 knockout (KO) mice, respectively. In order to study the effects of APP and its proteolytic product Abeta on Fragile X syndrome (FXS) phenotypes, we created a novel mouse model (FRAXAD) that over-expresses human APPSwe/Abeta in an fmr-1 KO background. Herein, we assess (1) human APP(Swe) and Abeta levels as a function of age in FRAXAD mice, and (2) seizure susceptibility to pentylenetetrazol (PTZ) after mGluR(5) blockade. PTZ-induced seizure severity is decreased in FRAXAD mice pre-treated with the mGluR(5) antagonist MPEP. These data suggest that Abeta contributes to seizure incidence and may be an appropriate therapeutic target to lessen seizure pathology in FXS, Alzheimer's disease (AD) and Down syndrome (DS) patients.
A fuzzy relative of the isodata process and its use in detecting compact well-separated clusters (1973)

Abstract Two fuzzy versions of the k-means optimal, least squared error partitioning problem are formulated for finite subsets X of a general inner product space. In both cases, the extremizing solutions are shown to be fixed points of a certain operator T on the class of fuzzy, k-partitions of X, and simple iteration of T provides an algorithm which has the descent property relative to the least squared error criterion function. In the first case, the range of T consists largely of ordinary (i.e. non-fuzzy) partitions of X and the associated iteration scheme is essentially the well known ISODATA process of Ball and Hall. However, in the second case, the range of T consists mainly of fuzzy partitions and the associated algorithm is new; when X consists of k compact well separated (CWS) clusters, Xi , this algorithm generates a limiting partition with membership functions which closely approximate the characteristic functions of the clusters Xi . However, when X is not the union of k CWS clusters, the limi...
ChemInform Abstract: UMLAGERUNGEN VON SILICIUMIONEN IM MASSENSPEKTROMETER, WANDERUNG ELEKTRONEGATIVER GRUPPEN VOM KOHLENSTOFF ZUM SILICIUM (1970)

Abstract Bei den durch Elektronenstoß aus den Silylverbindungen (I) entstehenden Si‐Ionen (II) wandert die Gruppe R an das Si‐Atom.
Discriminant correlation analysis for feature level fusion with application to multimodal biometrics (2016)

In this paper, we present Discriminant Correlation Analysis (DCA), a feature level fusion technique that incorporates the class associations in correlation analysis of the feature sets. DCA performs an effective feature fusion by maximizing the pair-wise correlations across the two feature sets, and at the same time, eliminating the between-class correlations and restricting the correlations to be within classes. Our proposed method can be used in pattern recognition applications for fusing features extracted from multiple modalities or combining different feature vectors extracted from a single modality. It is noteworthy that DCA is the first technique that considers class structure in feature fusion. Moreover, it has a very low computational complexity and it can be employed in realtime applications. Multiple sets of experiments performed on various biometric databases show the effectiveness of our proposed method, which outperforms other state-of-the-art approaches.
Legume chains diagnosis for animal and human food and (some...) development prospects (2018)

prod ? EA équipe BAP GEAPSI INRA
Economic Impact of Alvimopan Considering Varying Definitions of Postoperative Ileus (2015)

The addition of alvimopan to existing treatment pathways for patients undergoing abdominal surgery can reduce overall hospital costs.
Influence of Bitter Taste on Mastication Pattern (2005)

Mastication is a rhythmic activity that can be modified by peripheral information generated in the mouth. To study whether taste cognition could influence the way in which a food is broken down in the mouth, subjects masticated firm, sugar-based gelatine gels with differing concentrations of quinine, up to 1500 micromol/kg, while electromyography (EMG) of masticatory muscles was recorded. Taste intensity and composition of saliva were measured. With increasing quinine concentration, the average number of chews for nine subjects decreased from 30 to 22, and their average clearance time increased from 7 to 14 sec. Quinine concentration had no effect on chewing frequency (1.3 Hz) or on the rate of salivation (5.5 g/min). Bitterness increased, while acceptability and sweetness decreased, with increasing concentration of quinine in the gel and in saliva. Taste cognition could therefore modify food breakdown in the mouth.
Efficiency comparison of a single-phase grid-interface bidirectional AC/DC converter for DC distribution systems (2015)

The focused bidirectional ac/dc converter works as the interface between dc distribution systems (future residential dc system, energy storage system etc.) and the ac utility. The interface converter regulates ac side current and dc side droop voltage. It also limits the current if ac or dc side is short. An design procedure is developed to optimize the efficiency of this interface converter. Different bidirectional 2-level and 3-level topologies with state of the art IGBTs and SiC MOSFETs are compared. The choice of switching frequency, inductor current ripple and passive components are optimized for each candidate. Grid interconnecting standards are used as the design requirements. The result shows the 2-level full-bridge topology with paralleled SiC MOSFETs has the highest efficiency. The 3-level T-type topology with hybrid devices (IGBTs and SiC MOSFETs) has a good trade-off between efficiency and passive volumes.
Basic Study of Detecting Defects in Solid Materials Using High-Intensity Aerial Ultrasonic Waves (2012)

Recently, developments have improved methods employing aerial ultrasonic waves for detecting defects in solid materials such as metals, pipe walls, and fiber-reinforced plastics. These methods can be performed using a noncontacting aerial ultrasonic probe. In a previous study, we developed a new method using high-intensity aerial ultrasonic waves to successfully detect peeling, artificially created by inserting an air gap between tiles and concrete plates. In the present study, we use the same method to detect the depth and size of defects in a homogeneous medium.
A Comparison of CT-Stereotaxic Brain Biopsy Techniques (1984)

The role that computed tomography plays in the stereotaxic biopsy of intracranial lesions is reviewed. The most useful techniques, apparatuses results, and complications are described. Major complications of the procedure are hemorrhage and edema. The risk of hemorrhage may be reduced by the use of angiography before stereotaxic procedures; the risk of edema may be reduced by using steroids. Design features of several representative systems are compared. Indications for this procedure are suggested.
Matching diagnosis and management of diabetes in pregnancy to local priorities and resources: An international approach (2011)

The International Association of the Diabetes and Pregnancy Study Groups' (IADPSG) criteria for the diagnosis and classification of hyperglycemia in pregnancy are described and application of these in differing healthcare contexts on a worldwide basis is reported. Existing local protocols and known epidemiologic and clinical data regarding the detection and management of overt diabetes and gestational diabetes in the context of human pregnancy are considered. Although the IADPSG criteria are uniform, their introduction poses a variety of practical and technical challenges in differing healthcare contexts, both between and within countries. Knowledge of local factors will be vital in the implementation of the new guidelines and will require extensive liaison with local clinical and health policy groups. Resource availability will be critical in determining the type of treatment available in this context. The IADPSG criteria offer an important opportunity for a uniform approach to diabetes in pregnancy. Scaled implementation of these criteria adapted to a variety of local healthcare contexts should improve both research endeavors and patient care.
Interleukin-1β-induced Ceramide and Diacylglycerol Generation 5 Lead to Activation of the c-Jun NH2-terminal Kinase and the Transcription Factor ATF2 in the Insulin-producing Cell Line RINm5F (1996)

The aim of this investigation was to study the putative involvement of lipid second messengers, protein kinases, and transcription factors in interleukin-1 beta (IL-1beta)-induced signal transduction in insulin-producing cells. For this purpose, insulin-producing RINm5F cells were exposed to IL-1beta (25 units/ml), and the ceramide, ceramide 1-phosphate, sphingomyelin, diacylglycerol, and phosphatidic acid contents of the cells were subsequently determined. It was found that IL-1beta induced a transient increase (2-5 min) in ceramide and diacylglycerol, which was not paralleled by an increase in ceramide 1-phosphate and phosphatidic acid. A rapid decrease in the sphingomyelin content of the cells was, however, observed. The cell-permeable ceramide analogue N-acetylsphingosine and the phorbol ester phorbol 12-myristate 13-acetate (PMA) both induced the phosphorylation and increased the activities of the protein kinase JNK1 and the transcription factor ATF2. These effects were, however, not as pronounced as those induced by IL-1beta. The DNA binding activity of transcription factors in nuclear extracts was determined using the electrophoretic mobility shift assay method. Transcription factor binding to the ATF/cAMP-responsive element consensus sequence was increased 4-5-fold by acetylsphingosine, PMA, or IL-1beta, whereas binding to the CCAAT/enhancer-binding protein and AP-1 elements was found to be only slightly stimulated by these three agents. Binding to the NF-kappaB element was strongly induced by IL-1beta, but not by acetylsphingosine or PMA. Finally, acetylsphingosine and PMA did not mimic the nitric oxide-inducing effects of IL-1beta. It is concluded that IL-1beta-stimulated formation of ceramide and diacylglycerol may contribute to JNK1 and ATF2 transcription factor activation, which may be a necessary (but not sufficient) step in beta-cell nitric-oxide synthase induction.
Histone modification analysis by chromatin immunoprecipitation from a low number of cells on a microfluidic platform (2011)

Histone modifications are important epigenetic mechanisms involved in eukaryotic gene regulation. Chromatin immunoprecipitation (ChIP) assay serves as the primary technique to characterize the genomic locations associated with histone modifications. However, traditional tube-based ChIP assays rely on large numbers of cells as well as laborious and time-consuming procedures. Here we demonstrate a novel microfluidics-based native ChIP assay which dramatically reduces the required cell number and the assay time by conducting cell collection, lysis, chromatin fragmentation, immunoprecipitation, and washing on a microchip. Coupled with real-time PCR, our assay permits the analysis of histone modifications from as few as ~50 cells within 8.5 h. We envision that our method will provide a new approach for the analysis of epigenetic regulations and protein-DNA interactions in general, based on scarce cell samples such as those derived from animals and patients.
Structural Regime Identification in Ionotropic Alginate Gels: Influence of the Cation Nature and Alginate Structure (2011)

The morphologies of several ionotropic alginate hydrogels and aerogels were investigated by SAXS according to the nature of the divalent metal cation (Mn(2+), Co(2+), Zn(2+), Cu(2+)) and the guluronic fraction of the alginate. All alginate hydrogel and aerogel samples show isotropic small-angle X-ray scattering. Gelation results from cooperative associations of cations and chain segments and yields different nanostructures, that is, nanofibrillar morphology or multiple junction morphology, according to cation type and eventually mannuronic/guluronic ratio. Therefore, Mn and Cu gels present the same morphology whatever the guluronic ratio, whereas Co and Zn gels yield different nanostructures. In the size range investigated by SAXS (~10-200 Å), the structure of aerogels obtained by CO(2) supercritical drying is found to be inherited from the morphology of the parent hydrogel whatever the initial structural regime.
Demonstration of PET System Design Trade-offs Using Small Lesion Detectability as a Metric and Measured Phantom Data (2017)

PET system design involves trade-offs between cost and performance. It is a combination of capabilities that define the clinical utility of any given system design. System sensitivity and time-of-flight (TOF) timing resolution are two such parameters that influence system performance and cost. It is important to quantify the trade-offs using clinically-relevant measures prior to selecting a design. A lesion detection phantom has previously been demonstrated and is used in this work to characterize the relationships between timing resolution or system sensitivity and model observer SNR. To summarize, doubling of NEMA sensitivity resulted in detectability improvement of the same order of magnitude as a halving of coincidence timing FWHM. The trend in detectability improvement as a function of sensitivity was predicted by a square root relationship while for timing improvement, the relationship was less than that predicted by a square root. Over the range of parameters studied, change in NEMA sensitivity produced more change in detectability than improvement in timing resolution from 550 to 200 ps.
INFLUENCE OF SPECIMEN GEOMETRY ON THE FATIGUE BEHAVIOR OF A CARBON FABRIC REINFORCED PPS (2012)

This manuscript studies the tension-tension fatigue behavior of a carbon fabric reinforced PPS and the influence of the specimen geometry on the obtained results. First, the fatigue experiments are preformed according to the ASTM D3479/D3479M standard using the rectangular shaped specimen, but virtually all specimens fail in the tabbed section. This, however, means that fatigue lifetime may be underestimated. Therefore, a new dumbbell-like shape was assessed. Based on the occurring stress concentrations in the tabbed section, the dog bone-like shape was first optimised numerically using FEM, and then, the optimised specimen was tested in tension-tension fatigue. It can be concluded that this dumbbell shape yields better results in terms of acceptable failure and that the used shape has a significant influence on the fatigue lifetime.
Atypická kožní mykobakterióza (2009)

Je popsan připad ženy s diagnozou atypicke kožni mykobakteriozy. Diagnoza byla stanovena na zakladě anamnezy, klinickeho obrazu,
kultivacniho průkazu Mycobacterium marinum a histologickeho nalezu granulomatozniho zanětu.
K lecbě byla pacientka předana na Kliniku plicnich nemoci a tuberkulozy LF UP a FN Olomouc, kde byla zavedena celkova terapie tuberkulostatiky.
Nasledně byla provedena excize nodulů na Odděleni plasticke a esteticke chirurgie LF UP a FN Olomouc. Lecba tuberkulostatiky
byla ukoncena po 5 měsicich. Doslo k uplnemu zhojeni.