gebhart/patrepeval huggingface dataset:
The individual versus the computer: an examination of attitude problems and their impact on system development (1981)

Whether rational or irrational in nature, negative feelings toward computer based systems have been a persistent problem for computer implementors and systems managers for many years. People may sometimes fear for the future of their employment, feel intimidated by a technology they do not understand, resent the invasion of privacy associated with indiscriminate data collection, or exhibit a wide variety of other emotional responses. In order to better anticipate, understand and cope with the multitude of emotional reactions and interface problems that potentially may develop among non-technical computer system users, current literature pertaining to such negative attitudes has been explored. With a greater understanding of possible human-computer interface problems, it is believed that managers, computer professionals, system users and social institutions alike can all assume important roles in helping to promote more universally positive interactions and attitudes in the future. (Author)
Epithelia derived from human mammary tissue exhibits unique ion transport characteristics (2009)

Ion transport and barrier characteristics of mammary epithelium are poorly defined for most species, including humans. MCF10a cells, derived from non‐neoplastic human mammary tissue (Cancer Res 50: 6075, 1990), were cultured on permeable supports in typical medium (DMEM/F12) for 9‐17 days in the absence and presence of cholera toxin (Ct). At all time points tested, MCF10a cells generated an electrically tight epithelial barrier (1010±110 O cm 2 ) that exhibited a positive short circuit current (Isc; 6.1±0.3 μA cm −2 ) indicative of net cation absorption or anion secretion. Cells cultured in Ct exhibited greater basal Isc and greater amiloride‐sensitive Isc (4.3 vs. 2.5 μA cm −2 ), indicating enhanced sodium absorption. Culturing the cells in the presence of forskolin (0.2 μM) did not replicate the Ct effect. Additionally, it was shown that the effect of Ct‐enhanced amiloride‐sensitive Isc was greatest at the shortest exposure period tested, 1 day. Regardless of culture conditions, acute exposure to forskolin (2 μM) induced a modest, slowly developing increase in Isc. Bumetanide and glibenclamide (300 μM) were associated with modest reductions in Isc (&lt;0.7 μA cm −2 ). These results demonstrate that MCF10a cells provide a valuable model to identify transport mechanisms and regulatory pathways that can account for the unique composition of human milk. [NIH (P20‐ RR017686 ), KS Ag Exp Stn, and KSU SUROP support]
Agent-Based E-Supply Chain Decision Support (2003)

The global Internet economy is expected over time to give rise to increasingly agile practices where new supply chain arrangements are dynamically set up in response to changing business conditions and demands for highly customized products and services. To implement these “e-Supply Chain” practices, enterprises need the ability to rapidly evaluate new business opportunities and dynamically identify the best potential supply chain partners to respond to them. They also need the ability to effectively coordinate production and delivery of goods or services across the resulting value chains. In this paper, we introduce MASCOT, an agent-based decision support environment for dynamic supply chain management. MASCOT agents help users distributed across multiple organizations and across different levels within a given enterprise to collaborate on the development and revision of supply chain solutions, as they evaluate different business opportunities (e.g. requests for bids from potential customers) and different sourcing options. The paper also discusses new coordination protocols, developed within the context of MASCOT and aimed at better exploiting the power of finite capacity scheduling functionality across the supply chain. Empirical results are presented quantifying the benefits afforded by these new protocols under different loads and supply chain configurations.
Feature-based segmentation of narrative documents (2005)

In this paper we examine topic segmentation of narrative documents, which are characterized by long passages of text with few headings. We first present results suggesting that previous topic segmentation approaches are not appropriate for narrative text. We then present a feature-based method that combines features from diverse sources as well as learned features. Applied to narrative books and encyclopedia articles, our method shows results that are significantly better than previous segmentation approaches. An analysis of individual features is also provided and the benefit of generalization using outside resources is shown.
RADIATION DOSE WITH CIRCULAR EXTERNAL FIXATION: DOES THE SURGEON GET A DOUBLE WHAMMY? (2023)

Introduction The vast majority of orthopaedic surgeons use C-arm fluoroscopy in the operating theatre when building a circular external fixator. In the absence of previous research in this area, we hypothesised that the surgeon who builds a circular external fixator is exposed to a greater amount of radiation purely as a result of the presence of the metallic fixator in the x-ray beam. The aim of our study therefore was to investigate how the presence of a circular external fixator affects the radiation dose to the surgeon and the surgical assistant. Materials &amp; Methods A simulated environment was created using a radiolucent operating table, an acrylic lower limb phantom (below knee segment), various configurations of metalic circular external fixation, and a standard size C-arm image intensifier. The variables investigated were 1. the amount of metal in the beam 2. the orientation of the beam (PA vertical vs lateral) 3. the horizonal distance of the person from the beam (surgeon vs assistant) and 4. the vertical distance of the various body parts from the beam (e.g. thyroid, groin). In terms of radiation dose, we recorded two things : 1. the dose produced by the image intensifier 2. the dose rate at standardised positions in the operating theatre. The latter was done using a solid-state survey sensor. These positions represented both where the surgeon and surgical assistant typically stand plus the heights of their various body regions relative to the operating table.. Results The effect of the presence of the circular external fixator : all frame constructs tested resulted in a statistically significant greater radiation dose both produced by the image intensifier and received by the surgical team. The effect of the beam orientation : the PA (vertical) orientation resulted in a statistically significant greater radiation dose for the surgeon than did the lateral orientation, but made no difference for the assistant. The effect of horizontal distance from the beam : unsurprisingly, the surgeon (who was closer to the beam) received a statistically significant greater radiation dose than the assistant. The effect of vertical distance from the beam : for the surgeon, the dose received was highest at the level of the phantom leg / frame, whilst for the assistant there was no statistically significant difference for any level. Conclusions To our knowledge, this is the first study investigating the radiation dose rate to the orthopaedic surgeon when building a circular external fixator. We found that the surgeon does indeed receive a ‘double whammy’ because the image intensifier puts out a greater amount of radiation plus the metalic frame scatters more of the x-ray beam. Whilst the amounts are relatively small, we think that it's important to quantify doses that orthopaedic surgeons receive to ensure optimal radiation practices.
Computing Chromatic Adaptation (2005)

Most of today’s chromatic adaptation transforms (CATs) are based on a modified form of the von Kries chromatic adaptation model, which states that chromatic adaptation is an independent gain regulation of the three photoreceptors in the human visual system. However, modern CATs apply the scaling not in cone space, but use “sharper” sensors, i.e. sensors that have a narrower shape than cones. The recommended transforms currently in use are derived by minimizing perceptual error over experimentally obtained corresponding color data sets. We show that these sensors are still not optimally sharp. Using different computational approaches, we obtain sensors that are even more narrowband. In a first experiment, we derive a CAT by using spectral sharpening on Lam’s corresponding color data set. The resulting Sharp CAT, which minimizes XYZ errors, performs as well as the current most popular CATs when tested on several corresponding color data sets and evaluating perceptual error. Designing a spherical sampling technique, we can indeed show that these CAT sensors are not unique, and that there exist a large number of sensors that perform just as well as CAT02, the chromatic adaptation transform used in CIECAM02 and the ICC color management framework. We speculate that in order to make a final decision on a single CAT, we should consider secondary factors, such as their applicability in a color imaging workflow. We show that sharp sensors are very appropriate for color encodings, as they provide excellent gamut coverage and hue constancy. Finally, we derive sensors for a CAT that provide stable color ratios over different illuminants, i.e. that only model physical responses, which still can predict experimentally obtained appearance data. The resulting sensors are sharp.
Long-Term Follow-Up of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy (2020)

Complete remissions of a variety of B-cell malignancies lasting ≥ 3 years occurred after 51% of evaluable anti-CD19 CAR T-cell treatments. Remissions of up to 9 years are ongoing. Late adverse events were rare.
User engagement in online News: Under the scope of sentiment, interest, affect, and gaze (2014)

Online content providers, such as news portals and social media platforms, constantly seek new ways to attract large shares of online attention by keeping their users engaged. A common challenge is to identify which aspects of online interaction influence user engagement the most. In this article, through an analysis of a news article collection obtained from Y ahoo N ews US , we demonstrate that news articles exhibit considerable variation in terms of the sentimentality and polarity of their content, depending on factors such as news provider and genre. Moreover, through a laboratory study, we observe the effect of sentimentality and polarity of news and comments on a set of subjective and objective measures of engagement. In particular, we show that attention, affect, and gaze differ across news of varying interestingness. As part of our study, we also explore methods that exploit the sentiments expressed in user comments to reorder the lists of comments displayed in news pages. Our results indicate that user engagement can be anticipated predicted if we account for the sentimentality and polarity of the content as well as other factors that drive attention and inspire human curiosity.
Likelihood Contribution based Multi-scale Architecture for Generative\n Flows (2019)

Deep generative modeling using flows has gained popularity owing to the\ntractable exact log-likelihood estimation with efficient training and synthesis\nprocess. However, flow models suffer from the challenge of having high\ndimensional latent space, the same in dimension as the input space. An\neffective solution to the above challenge as proposed by Dinh et al. (2016) is\na multi-scale architecture, which is based on iterative early factorization of\na part of the total dimensions at regular intervals. Prior works on generative\nflow models involving a multi-scale architecture perform the dimension\nfactorization based on static masking. We propose a novel multi-scale\narchitecture that performs data-dependent factorization to decide which\ndimensions should pass through more flow layers. To facilitate the same, we\nintroduce a heuristic based on the contribution of each dimension to the total\nlog-likelihood which encodes the importance of the dimensions. Our proposed\nheuristic is readily obtained as part of the flow training process, enabling\nthe versatile implementation of our likelihood contribution based multi-scale\narchitecture for generic flow models. We present such implementations for\nseveral state-of-the-art flow models and demonstrate improvements in\nlog-likelihood score and sampling quality on standard image benchmarks. We also\nconduct ablation studies to compare the proposed method with other options for\ndimension factorization.\n
Suggested methodology for longitudinal evaluation of nevi based on clinical images (2021)

Comparison of nevi from two different time points is more consistent than nevus count performed separately at each time point. In addition, except for selected cases, automated measurements of nevus diameter on 3D images can be used as a time-saving reproducible substitute for manual measurement on 2D images.
High-resolution 13C nuclear magnetic resonance studies of glucose metabolism in Escherichia coli. (1978)

High-resolution 13C nuclear magnetic resonance spectra of suspensions of Escherichia coli cells have been obtained at 90.5 MHz by using the Fourier transform mode. Anaerobic cells incubated with [I-13C]glucose show a time course of glycolysis in which the alpha and beta glucose anomers disappear at different rates, lactate, succinate, acetate, alanine, and valine accumulate as end products of glycolysis, and fructose bisphosphate appears as an intermediate. It is shown that fructose bisphosphate is labeled at C-1 and C-6 during [I-13C]-glucose catabolism. Upon oxygenation, glutamate appears with the 13C ENRICHMENT AT THE C-4, C-3, and C-2 positions, with the C-4 most intense. From the position of the 13C label we conclude that valine is formed by condensation of pyruvate and that carbon enters the tricarboxylic acid cycle mainly through acetyl CoA.
Mapping discontinuous permafrost in the Canadian Sub‐Arctic using a combination of airborne and surface geophysical surveys (2000)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 2000Mapping discontinuous permafrost in the Canadian Sub‐Arctic using a combination of airborne and surface geophysical surveysAuthors: Richard KellettAndrew HinnellJeff GameyGreg HodgesRichard KellettKomex International Ltd., Andrew HinnellKomex International Ltd., Jeff GameyVanguard Geophysics Ltd., and Greg HodgesFugro Airborne Surveyshttps://doi.org/10.1190/1.1815649 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1815649FiguresReferencesRelatedDetails SEG Technical Program Expanded Abstracts 2000ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 2000 Pages: 2484 publication data© 2000 Copyright © 2000 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished: 04 Jan 2005 CITATION INFORMATION Richard Kellett, Andrew Hinnell, Jeff Gamey, and Greg Hodges, (2000), "Mapping discontinuous permafrost in the Canadian Sub‐Arctic using a combination of airborne and surface geophysical surveys," SEG Technical Program Expanded Abstracts : 1351-1354. https://doi.org/10.1190/1.1815649 Plain-Language Summary PDF DownloadLoading ...
Analysis of Cyber Attacks Against Micro-PMUs: The Case of Event Source Location Identification (2020)

This paper investigates cyber-attacks against distribution-level phasor measurement units, a.k.a., micro-PMUs. The focus is on a specific use case of micro-PMUs for locating the source of events in distribution systems. A method is proposed to detect the attack, based on two different detection criteria. Furthermore, a novel optimization-based algorithm is developed to identify which micro-PMU(s) are compromised. Importantly, the proposed attack detection and identification methods do not require prior knowledge on the number and location of affected micro-PMU(s). The proposed methods and algorithms are test through computer simulations on the IEEE 33-bus test system.
Improvement of dichroic polymer dispersed liquid crystal performance using lift-off technique (2006)

A lift-off method has been developed for the fabrication of polymer dispersed liquid crystal (PDLC) displays. A polymer matrix template can be prefabricated by lifting off a PDLC film from a fluorosilanized antisticking substrate. Desirable liquid crystal can then be backfilled/infiltrated into the template. Applying this technique to fabricate dichroic PDLC yielded a reflectivity of 66% and a contrast ratio of 13.8:1 in 3.8in. quarter video graphics array reflective thin film transistor (TFT) displays. A diffuse layer with melamine-formaldehyde nanoparticles was employed to suppress the metallic glare caused by the reflective back plane. The technique is suitable for various back planes such as flexible, solvent/UV-sensitive, organic TFTs.
Differential Extraction and GC-MS based Quantification of Sesquiterpenoids from Immature Heartwood of East Indian Sandalwood Tree (2012)

The East Indian sandalwood tree yields the costliest heartwood and essential oil that are used in traditional medicine, aromatherapy and in cosmetic and fragrance industries. Steam distillation is the traditional method employed for extraction of the sesquiterpenoid rich essential oil from chips of matured heartwood. However, there is no information available on the comparative extractability of sesquiterpenoids when different solvents are employed. Thus we used four different solvents to extract, detect and quantify fourteen major sesquiterpenoids from immature heartwood, by gas chromatography- mass spectrometry (GC- MS) method employing an ion trap quadruple (ITQ) mass analyzer. Results suggest that, with increasing solvent polarity the diversity of sesquiterpenoids decreased, but the quantities of santalols increased. Moreover, n-hexane remained the best extraction solvent for santalols, i.e., yielding up to 92.6 % of total sesquiterpenoids quantified. Furthermore, Z-?-trans-bergamotol, Z-epi-?-santalol and Z-?-santalols were found to be the most abundant constituents of immature heartwood. Keywords: GC-MS, heartwood, Santalum album , sesquiterpenoid, solvent
Placental lesions associated with acute atherosis (2014)

Acute atherosis is associated with increased risks of having placental lesions consistent with MVU, and to a lesser extent, chronic chorioamnionitis and those consistent with FVTOD.
FuPlex: A Full Duplex MAC for the Next Generation WLAN (2015)

IEEE 802.11 wireless local area network (WLAN) has been increasingly developed over several decades. It requires four times throughput improvement in the next generation WLAN. Thus, researchers focus on the co-frequency co-time full duplex technology, which makes the devices transmit and receive pac
Unsupervised discovery of co-occurrence in sparse high dimensional data (2010)

An efficient min-Hash based algorithm for discovery of dependencies in sparse high-dimensional data is presented. The dependencies are represented by sets of features co-occurring with high probability and are called co-ocsets. Sparse high dimensional descriptors, such as bag of words, have been proven very effective in the domain of image retrieval. To maintain high efficiency even for very large data collection, features are assumed independent. We show experimentally that co-ocsets are not rare, i.e. the independence assumption is often violated, and that they may ruin retrieval performance if present in the query image. Two methods for managing co-ocsets in such cases are proposed. Both methods significantly outperform the state-of-the-art in image retrieval, one is also significantly faster.
Molecular Epidemiology of Tick-borne Encephalitis Virus: Peptide Mapping of Large Non-structural Proteins of European Isolates and Comparison with Other Flaviviruses (1982)

Nine virus-specified proteins were identified by SDS-polyacrylamide gel electrophoresis in [35S]methionine-labelled chick embryo cells infected with tick-borne encephalitis (TBE) virus by comparison with mock-infected cells. These proteins were designated P91, p74, p72, P67, GP53(E), P47, p25, P15(C) and P14.5 according to their molecular weights. Peptide mapping of P91, P67, GP53(E) and P47 from TBE virus-infected cells, as well as those of the corresponding proteins from West Nile virus (WNV)-infected cells (previously termed NV5, NV4, V3 and NV3), demonstrated the uniqueness of these proteins. Almost no subtype variability, with respect to the pattern of intracellular proteins, was found when isolates of TBE virus from Austria, Switzerland, Germany, Finland and Czechoslovakia were compared. Peptide mapping of NV5 (P91) and NV4 (P67) from all these isolates using limited proteolysis with alpha-chymotrypsin and V8 protease revealed completely identical patterns, thus extending our observations that TBE virus seems to represent a very stable member of the flavivirus genus, which was based on the lack of variation found with the structural glycoprotein. On the other hand, the Far Eastern subtype of TBE virus and the closely related louping-ill virus could not only be differentiated from the Western subtype by differences in the peptide maps of their structural glycoprotein but also in those of the non-structural protein NV5, i.e. subtype or subgroup variations are not confined to the virion surface glycoprotein. WNV and Murray Valley encephalitis virus (MVEV) revealed the expected heterogeneity of virus-specified proteins found in cells infected with different flaviviruses. It is especially interesting that also the largest non-structural protein, NV5, is subject to this heterogeneity, ranging in mol. wt. from 91 000 for TBE virus to 98 000 for MVEV and that also the peptide maps of NV5, as well as those of NV4, were unrelated. These proteins, therefore, revealed a variability between serologically distinct flaviviruses similar to that observed with the structural glycoprotein.
Design of audio signal processing and display system based on SoC (2015)

In order to realize the real-time and efficiency of audio processing, as well as reducing the complexity of the waveform display processing, this paper designs a system of audio signal processing and display based on SoC. Using the Xilinx zynq-7000 development platform and taking advantage of efficient parallel processing capability of FPGA, it enables to do the real-time audio signal processing, and realize the volume adjustment, audio effect control and amplitude frequency conversion. In addition, due to the advantages in complexity control of ARM, the system can achieve the real-time dynamic output of the audio waveform with the method of combining software and hardware.
Synergistic T cell signaling by 41BB and CD28 is optimally achieved by membrane proximal positioning within parallel chimeric antigen receptors (2021)

Second generation (2G) chimeric antigen receptors (CARs) contain a CD28 or 41BB co-stimulatory endodomain and elicit remarkable efficacy in hematological malignancies. Third generation (3G) CARs extend this linear blueprint by fusing both co-stimulatory units in series. However, clinical impact has been muted despite compelling evidence that co-signaling by CD28 and 41BB can powerfully amplify natural immune responses. We postulate that effective dual co-stimulation requires juxta-membrane positioning of endodomain components within separate synthetic receptors. Consequently, we designed parallel (p)CARs in which a 2G (CD28+CD3ζ) CAR is co-expressed with a 41BB-containing chimeric co-stimulatory receptor. We demonstrate that the pCAR platform optimally harnesses synergistic and tumor-dependent co-stimulation to resist T cell exhaustion and senescence, sustaining proliferation, cytokine release, cytokine signaling, and metabolic fitness upon repeated stimulation. When engineered using targeting moieties of diverse composition, affinity, and specificity, pCAR T cells consistently elicit superior anti-tumor activity compared with T cells that express traditional linear CARs.