gebhart/patrepeval huggingface dataset:
Effects of a Psychophysiological System for Adaptive Automation on Performance, Workload, and the Event-Related Potential P300 Component (2003)

The present study examined the effects of an electroencephalographic- (EEG-) based system for adaptive automation on tracking performance and workload. In addition, event-related potentials (ERPs) to a secondary task were derived to determine whether they would provide an additional degree of workload specificity. Participants were run in an adaptive automation condition, in which the system switched between manual and automatic task modes based on the value of each individual's own EEG engagement index; a yoked control condition; or another control group, in which task mode switches followed a random pattern. Adaptive automation improved performance and resulted in lower levels of workload. Further, the P300 component of the ERP paralleled the sensitivity to task demands of the performance and subjective measures across conditions. These results indicate that it is possible to improve performance with a psychophysiological adaptive automation system and that ERPs may provide an alternative means for distinguishing among levels of cognitive task demand in such systems. Actual or potential applications of this research include improved methods for assessing operator workload and performance.
N-Heterocyclic carbene functionalized MCM-41 as an efficient catalyst for chemical fixation of carbon dioxide (2011)

N-Heterocyclic carbene (NHC) functionalized MCM-41 was synthesized by reacting 1,3-bis-(4-allyl-2,6-diisopropylphenyl) imidazolium chloride with MCM-41 using 3-mercaptopropyltrimethoxysilane as silane coupling agent, and its CO2 adduct (designated as MCM-41-IPr-CO2) was further synthesized by the reaction with CO2. In situdiffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) was used to investigate the reversible CO2 capture-release ability of MCM-41-NHC. MCM-41-IPr-CO2 adduct proved to be an efficient heterogeneous catalyst for the cycloaddition of CO2 to epoxides or aziridines with excellent regioselectivity under mild conditions. Moreover, the catalyst could be recovered easily through a simple filtration process and reused multiple times without obvious loss in activity, owing to CO2 as protective group for effectively stabilizing the NHC anchored on MCM-41.
Remote detection of explosives using Field Asymmetric Ion Mobility Spectrometer installed on multicopter (2020)

The detection of explosives and drugs in hard-to-reach places is a considerable challenge. We report the development and initial experimental characterization of the air analysis system that includes Field Asymmetric Ion Mobility Spectrometer (FAIMS), array of the semiconductor gas sensors and is installed on multicopter. The system was developed based on the commercially available DJI Matrix 100 platform. For data collection and communication with operator, the special compact computer (Intel Compute Stick) was installed onboard. The total weight of the system was 3.3 kg. The system allows the 15 minutes flight and provide the remote access to the obtained data. The developed system can be effectively used for the detection of impurities in the air, ecology monitoring, detection of chemical warfare agents and explosives, what is especially important in light of recent terroristic attacks. The capabilities of the system was tested on the several explosives such as trinitrotoluene and nitro powder.
Perspectives of Ionic Liquids Applications for Clean Oilfield Technologies (2011)

Ionic liquids (ILs) are gaining wide recognition as potential environmental solvents due to their unique properties (Wasserscheid & Keim, 2004, Martinez-Palou, 2007, Martinez-Palou, 2010) and their applications in Organic Synthesis (Wasserscheid & Welton, 2008, MartinezPalou, 2006), catalysis (Gu et al., 2009, Toma et al., 2009, Olivier-Bourbigou, 2010), biocatalysis (Muginova et al., 2010, Moniruzzaman et al., 2010), in separation (Han & Row 2010), extraction (Poole & Poole, 2010) and dissolution processes (Torimoto et al., 2010, Zakrzewska et al., 2010), nanomaterials synthesis (Li et al., 2008), polymerization reactions (Srivastava, et al., 2009, Lu et al., 2009) and electrochemistry (McFarlane et al. 2010, Ohno & Fukumoto, 2008). ILs are an excellent alternative to substitute volatile organic solvents in more environmental friendly technologies, also known as “green technologies” (Rogers & Seddon, 2002) since their very low vapor pressures, their thermal and chemical stability, their ability to act as catalysts, and their non-flammability and non-corrosive properties which decreases the risk of worker exposure and the loss of solvent to the atmosphere. Petroleum industry is one of the most important industry in the world and in the last decades it has enter in a continuous process of modernization and transition for becoming to a more clean and “green industry” around the world. This industry present typical operational and old technological problems, like corrosion, emulsions formation (oil/water and water/oil), asphaltenes flocculation during oil production and processing, contamination of hydrocarbons feeds and other which need new and more efficient solutions (Speight, 2009). For their versatility and properties, ILs have a wide range of potential applications for chemical industry and especially for petroleum industry, as have been demonstrate with the increased number of papers about the evaluation of ILs for applications in areas as improvement of petroleum properties for their exploration, exploitation and transportation, elimination of toxic substances from fuels (sulfurated, nitrogenated and aromatics compounds), develop of new “green” additives with application as corrosion inhibitors, demulsifier and desalting agents, and several applications of the ILs as catalysts and solvents for petrochemical processes. ILs have also been explored in membranes technologies for selective separation of gases, liquids fuels and contaminants, and in another alternative fuels technologies like biofuels and fuel cells. In this chapter, some of the most important advances about the study of ILs for potential oilfield applications are reviewed.
The Power of Menus in Contract Design (2023)

We study the power of menus of contracts in principal-agent problems with adverse selection (agents can be one of several types) and moral hazard (we cannot observe agent actions directly). For principal-agent problems with T types and n actions, we show that the best menu of contracts can obtain a factor Ω (max(n, log T)) more utility for the principal than the best individual contract, partially resolving an open question of Guruganesh et al. [2021]. We then turn our attention to randomized menus of linear contracts, where we likewise show that randomized linear menus can be Ω(T) better than the best single linear contract. As a corollary, we show this implies an analogous gap between deterministic menus of (general) contracts and randomized menus of contracts (as introduced by Castiglioni et al. [2022]).
Pipe Provers: A User's Manual (1991)

Historical introduction general principles the pipe prover as part of a metering installation pulse interpolation how to calibrate pipe provers how to operate pipe provers research and development.
KEYNOTE-365 cohort B: Pembrolizumab (pembro) plus docetaxel and prednisone in abiraterone (abi) or enzalutamide (enza)–pretreated patients with metastatic castration-resistant prostate cancer (mCRPC)—New data after an additional 1 year of follow-up. (2021)

10 Background: For men with mCRPC, systemic therapies such as docetaxel and cabazitaxel improve survival, but more effective treatments are needed. KEYNOTE-365 (NCT02861573) is a phase 1b/2 study to examine the safety and efficacy of pembro in combination with 4 different study medications (cohorts A, B, C, D) in mCRPC. Previous data from cohort B with a median of 20 months of follow-up showed that pembro + docetaxel and prednisone was well tolerated and had antitumor activity in patients (pts) with mCRPC previously treated with abi or enza. New efficacy and safety data after an additional year of follow-up are presented. Methods: Cohort B enrolled pts who did not respond to or were intolerant to ≥4 weeks of abi or enza in the prechemotherapy mCRPC state and whose disease progressed within 6 months of screening (determined by PSA progression or radiologic bone/soft tissue progression). Pts received pembro 200 mg IV every 3 weeks (Q3W), docetaxel 75 mg/m 2 IV Q3W, and oral prednisone 5 mg twice daily. Primary end points were safety, PSA response rate (PSA decrease &gt;50% from baseline), and ORR per RECIST v1.1 by blinded independent central review. Efficacy and safety were assessed in all pts as treated. Results: Of the 104 treated pts, median age was 68.0 years (range, 50-86), 23.1% had PD-L1–positive tumors (combined positive score ≥1), 25.0% had visceral disease, and 50.0% had measurable disease. Median time from enrollment to data cutoff was 32.4 months (range 13.9-40.3); 101 pts discontinued, primarily because of disease progression (77.9%). Efficacy outcomes are reported in the table below. Treatment-related adverse events (TRAEs) occurred in 100 pts (96.2%); the most frequent (≥30%) were diarrhea (41.3%), fatigue (41.3%), and alopecia (40.4%). Grade 3-5 TRAEs occurred in 46 pts (44.2%). Five pts (4.8%) died of AEs; 2 were treatment-related pneumonitis. Conclusions: After another year of follow-up, pembro + docetaxel and prednisone showed improved ORR and PSA response rates compared to the prior dataset in pts with mCRPC previously treated with abi or enza. Safety was consistent with known profiles of each agent and will be further evaluated in a phase 3 study (KEYNOTE-921). Clinical trial information: NCT02861573. [Table: see text]
Zur Stereochemie des koordinativ vierwertigen Nickels (1936)

Abstract Es wurden aus alkoholischen Losungen von Nickelsalzen und Trialkylphosphinen Nickelverbindungen vom Typus [NiX 2 (R 3 P) 2 ] (X = Cl, Br, J. R = C 2 H 5 , C 3 H 7 , C 4 H 9 ) dargestellt. Von Triäthyl‐arsin wurde eine wenig beständige Verbindung [Ni J,(Ä 3 As) 2 ] erhalten. Die Chloride und Bromide sind dunkelrot, die Jodide dunkelbraun. Diese Verbindungen haben niedrige Schmelzpunkte und sind in organischen Lösungsmitteln sehr leicht löslich. Die Bestimmung ihrer Dipolmomente in benzolischer Losung ergab, daß sie nicht oder nur sehr wenig von O verschieden sind. Die Verbindungen besitzen demgemäß transplanare Konfiguration.
Insertion of operation-and-indicate instructions for optimized SIMD code (2023)

Mechanisms are provided for inserting indicated instructions for tracking and indicating exceptions in the execution of vectorized code. A portion of first code is received for compilation. The portion of first code is analyzed to identify non-speculative instructions performing designated non-speculative operations in the first code that are candidates for replacement by replacement operation-and-indicate instructions that perform the designated non-speculative operations and further perform an indication operation for indicating any exception conditions corresponding to special exception values present in vector register inputs to the replacement operation-and-indicate instructions. The replacement is performed and second code is generated based on the replacement of the at least one non-speculative instruction. The data processing system executing the compiled code is configured to store special exception values in vector output registers, in response to a speculative instruction generating an exception condition, without initiating exception handling.
4.5.3 A Comparison Study in Software Requirements Negotiation (1998)

ABSTRACT In a period of two years, two rather independent experiments were conducted at the University of Southern California. In 1995, 23 three‐person teams negotiated the requirements for a hypothetical library system. Then in 1996, 14 six‐person teams negotiated the requirements for real multimedia related library systems. A number of hypotheses were created to test how real software projects differ from hypothetical ones. Other hypotheses address differences in uniformity and repeatability. The results indicate that repeatability in 1996 was even harder to achieve then in 1995 (Egyed‐Boehm, 1996). Nevertheless, this paper presents some surprising commonalties between both years that indicate some areas of uniformity. In both years, the same overall development process (spiral model) was followed, the same negotiation tools (WinWin System) were used, and the same people were doing the analysis of the findings. Thus, the comparison is less blurred by fundamental differences like terminology, process, etc.
Common expression analysis in database applications (1982)

Independent optimization of database requests overlooks potential savings which can be achieved when they are optimized collectively. An intuitive model for queries called the query graph supports common expression detection for optimization of a stream of requests. We describe how ad hoc query processing can be improved using intermediate results and answers produced from earlier queries, without significantly impacting processing costs when no common expressions are found. We have written a Pascal program, COMMON, which implements a variation of the algorithm which we describe.
Evaluation system for residual vibration from HDD mounting mechanism (1999)

An evaluation system for calculating the residual vibration caused by a HDD (Hard Disk Drive) mounting system is presented. It contains both the elements for measurement and analysis. The PES (Position Error Signal) of an ideally balanced rigid rotary actuator depends on the rotational vibration of the HDD, specifically at lower frequencies. First, this evaluation technique obtains a measurement of the transfer function of the HDD rotational acceleration over actuator current. Next, using the measured power spectrum of the actuator in combination with the HDD's tracking error transfer function, the response of the entire HDD and mount system is calculated in the frequency domain. Finally the time domain system response is calculated by computation of the Inverse Fast Fourier Transform (IFFT) of the frequency response solution, assuming a random phase of the input force. Good correlation is obtained between measured and calculated system responses. Experimental result show that the dominant residual vibration is caused by the mounting mechanism response and that both the HDD and HDD mount system need to be evaluated and understood as a system, in order to achieve higher TPI (Track per inch) in the future.
Non-local power wave transformations using Omega Bianisotropic Huygens’ Metasurface Pairs (2019)

Omega bianisotropic Huygens’ metasurfaces (BHMs) are subwavelength thin sheets that have been used in applications such as wide-angle reflectionless refraction of plane waves, and wideband matching between dielectric media. However, for the BHM design to be passive, reflectionless and lossless, the wave transformation is restricted to conserve local power at every point over the metasurface. For non-local power transformations, pairs of BHMs can be engineered, with a separation between them, to re-distribute the local power profile at will. This opens the possibilities to a multitude of wave transformations that conserve the global power, but not necessarily the local power at every point. This paper presents two non-local power transformations that are realized with a paired BHM configuration, namely beam expansion and beamforming.
Supplementary Table 1 from The CXCL7/CXCR1/2 Axis Is a Key Driver in the Growth of Clear Cell Renal Cell Carcinoma (2023)

&lt;p&gt;PDF file - 54K, Clinical and biological parameters and univariate analysis of patients.&lt;/p&gt;
Comments on analyses of reflection gratings (1983)

The descriptions of diffraction by pure reflection gratings (fringes parallel to surfaces) and by reflection gratings with slanted fringes are clarified. The rigorous coupled-wave analysis, the chain-matrix analysis, and the new method presented by Zylberberg and Marom [ J. Opt. Soc. Am.73, 392 ( 1983)] are compared and their regions of applicability determined. Zylberberg and Marom refer to their method as a coupled-wave analysis, a description that is inconsistent with previous use of this terminology.
CMOS current starved voltage controlled oscillator circuit for a fast locking PLL (2015)

Two novel voltage controlled oscillators (CSN-VCO and CSD-VCO) have been proposed in this paper. CSN-VCO has been designed with 20 transistors while CSD VCO with 24 transistors. It has been observed that CSN-VCO could operate in the frequency range from 0.066 to 2.2 GHz, and CSD VCO could operate from 0.047 to 2.5 GHz. Tuning range for these VCOs are determined to be 97 %, and 98.2 % while the values of gain obtained are 8.94 and 10.2 GradV−1 respectively. Phase noise analysis has been performed and the phase noise contribution by CSN-VCO and CSD VCO are found to be −126 and −129 dBc/Hz @ 1 MHz respectively. Prototype has been designed in Cadence virtuoso environment and implemented using GPDK090 library of 180 nm technology with a supply voltage of 1.8 V. Simulation of transfer function of PLL built with the VCOs has been done in MATLAB and the step response has been compared with the circuit simulation results from Cadence. Lock time as low as 355 ns and 313 ns have been achieved for the CSN-VCO and CSD-VCO respectively.
Perspective on this Article from Chromoendoscopy Detects More Adenomas than Colonoscopy Using Intensive Inspection without Dye Spraying (2023)

Perspective on this Article from Chromoendoscopy Detects More Adenomas than Colonoscopy Using Intensive Inspection without Dye Spraying
Database Issues for Data Visualization: IEEE Visualization '93 Workshop, San Jose, California, Usa, October 26, 1993 : Proceedings (1994)

Workshop description.- Workshop participants.- Database issues for data visualization: Developing a data model.- Database issues for data visualization: System integration issues.- Database issues for data visualization: Interaction, user interfaces, and presentation.- The VIS-AD data model: Integrating metadata and polymorphic display with a scientific programming language.- An extended schema model for scientific data.- Data integration for visualization systems.- Inherent logical structure of computational data: Its role in storage and retrieval strategies to support user queries.- Database management for data visualization.- Data exploration interactions and the ExBase system.- Database requirements for supporting end-user visualizations.- A system architecture for data-oriented visualization.- A Hyperspectral Image Data Exploration Workbench for environmental science applications.- Design of a 3D user interface to a database.- Visualizing reference databases.- A 3D based user interface for information retrieval systems.- Using visualization to support data mining of large existing databases.
The ion channel function of polycystin‐1 in the polycystin‐1/polycystin‐2 complex (2019)

Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutations in PKD1 or PKD2 gene, encoding the polycystic kidney disease protein polycystin-1 and the transient receptor potential channel polycystin-2 (also known as TRPP2), respectively. Polycystin-1 and polycystin-2 form a receptor-ion channel complex located in primary cilia. The function of this complex, especially the role of polycystin-1, is largely unknown due to the lack of a reliable functional assay. In this study, we dissect the role of polycystin-1 by directly recording currents mediated by a gain-of-function (GOF) polycystin-1/polycystin-2 channel. Our data show that this channel has distinct properties from that of the homomeric polycystin-2 channel. The polycystin-1 subunit directly contributes to the channel pore, and its eleven transmembrane domains are sufficient for its channel function. We also show that the cleavage of polycystin-1 at the N-terminal G protein-coupled receptor proteolysis site is not required for the activity of the GOF polycystin-1/polycystin-2 channel. These results demonstrate the ion channel function of polycystin-1 in the polycystin-1/polycystin-2 complex, enriching our understanding of this channel and its role in ADPKD.
Daya Saing Tembakau Virginia Lokal: Analisis Rantai Nilai (2014)

Tembakau Virginia merupakan bahan baku utama industri rokok Indonesia terutama digunakan untuk pembuatan rokok sigaret putih. Meningkatnya impor tembakau Virginia secara langsung maupun tidak langsung berpengaruh terhadap produksi tembakau sejenis di dalam negeri. Studi ini mengkaji kemampuan daya saing tembakau Virginia local dengan menggunakan analisis rantai nilai (value chain). Metode Value Chain Analysis (VCA) digunakan untuk mengetahui keterkaitan yang ada dalam rantai nilai. Data yang dipakai adalah data dari penelitian yang dilakukan di dua daerah yaitu Bojonegoro (Jawa Timur) dam Lombok Timur (Nusa Tenggara Barat). Produksi dalam negeri belum bisa memasok sepenuhnya kebutuhan industri rokok dalam negeri, karena terbatasnya jumlah produksi, rendahnya kualitas tembakau yang dihasilkannya dan kontinyuitas pasokan tembakau. Rantai distribusi yang panjang menyebabkan harga yang tidak kompetitif dan kualiatas yang menurun, sehingga daya saingnya lebih rendah. Kebijakan intensifikasi lahan merupakan pilihan yang harus ditempuh daerah penghasil tembakau dengan terus meningkatkan kualitas tembakau yang dihasilkannya, sehingga produksi dan produktivitasnya meningkat untuk memenuhi pasokan tembakau virginia di dalam negeri.
Signaling from toxic metals to NF-kappaB and beyond: not just a matter of reactive oxygen species. (2002)

The nuclear factor kappa B (NF-kappaB) family of transcription factors controls expression of a number of early response genes associated with inflammatory responses, cell growth, cell cycle progression, and neoplastic transformation. These genes include a multitude of cytokines, chemokines, adhesion molecules, immune receptors, stress proteins, apoptotic or anti-apoptotic regulators, and several oncogenes. Accumulating evidence indicates that a variety of toxic metals are able to affect the activation or activity of NF-kappaB, but the molecular mechanisms involved in this process remain largely unknown. The signaling pathways mediating cytokine- or microorganism-induced NF-kappaB activation have been well established recently. Whether the same signaling systems are involved in metal-induced NF-kappaB activation, however, is unclear. In the present review, we have attempted to evaluate and update the possible mechanisms of metal signals on the activation and function of NF-kappaB.