gebhart/patrepeval huggingface dataset:
Performance of adaptive Volterra equalizers on nonlinear magnetic recording channels (1995)

We examine the error rate performance of various equalizers on two nonlinear channel models which have been proposed recently in the literature: a partial erasure model and a Volterra model. We find that when the noise is appreciable the performance of the Volterra equalizer is only slightly better than that of a linear equalizer. Our results also demonstrate that write precompensation for transition shift elimination is to be preferred over post-compensation.
Possibility of Interchanging Patients for Beam-Matched Linear Accelerators from the Same Vendor (2019)

The purpose of this study is to investigate the possibility of interchanging patients on beam-matched linear accelerators (linacs), by evaluating the dosimetric variation and the dose delivery accuracy of volumetric modulated arc therapy (VMAT). Two VitalBeam linacs installed recently in our center were included in this study. For dosimetric data comparison, beam data, such as percentage depth doses (PDDs), beam profiles, output factors, multi-leaf collimator (MLC) leaf transmission factors, and the dosimetric leaf gap (DLG), for 6-MV and 10-MV beams were measured on both linacs. Sixty patients (20 head and neck, 20 lung, and 20 prostate cancers) were selected to evaluate the dosimetric parameters and the delivery accuracy of the VMAT plans created for various treatment sites. All the VMAT plans were generated using the Eclipse treatment planning system (TPS) with the same optimizer algorithm. The dose differences between two beam-matched linacs for planning target volumes (PTVs) and organs at risk (OARs) were recorded and analyzed. Patient-specific dosimetric quality assurance (DQA) using the Electronic Portal Image Device (EPID) were performed, and the measured planar doses were compared with those calculated by using the TPS though absolute dose gamma evaluation using 2%/2 mm and 2%/3 mm criteria. The differences in all dosimetric beam data between the two beam-matched linacs were all within 1% for the 6-MV and the 10-MV beams. For all 60 cases of three treatment sites, no notable differences were observed in the dosimetric comparison and the DVH variation between the beam-matched linacs. The average differences in dosimetric parameters of PTV and OARs were all within 1%. Furthermore, all passing rates of measured doses on the beam-matched linacs were higher than 93% and 97% for the 2%/2 mm and the 2%/3 mm criteria, respectively. Our overall dosimetric variation in beam data and VMAT plans remains within the tolerance of clinical acceptability. Pretreatment verification results were also clinically acceptable, showing good agreement with the calculated doses. Therefore, this study demonstrated the possibility of swapping patients in a VMAT plan without any modification and re-planning between two beam-matched linacs.
Severe Insulin-Resistance Hyperandrogenic Syndromes (2007)

Insulin resistance is associated with a wide variety of markedly heterogeneous clinical disorders, either inherited or acquired, that may result in acanthosis nigricans, ovarian hyperandrogenism, and ovulatory dysfunction. These include the type A (primarily affecting lean women and resulting from defects of the insulin receptor), type B (resulting from an autoimmune process affecting the insulin receptor), and type C (a variant of type A, the hyperandrogenic, insulin-resistant, and acanthosis nigricans [HAIR-AN] syndrome) insulin resistance syndromes. More rare syndromes include leprechaunism, the Rabson-Mendenhall syndrome, and a heterogeneous group of lipodystrophic syndromes. HAIR-AN is generally present in obese women who do not demonstrate defects of the insulin receptor, although they may exhibit postreceptor defects. Although the type A and B insulin resistance syndromes are rare causes of ovarian hyperandrogenism, type C may affect up to 3% of women with androgen excess. These patients may be treated as other women with ovarian hyperandrogenism, namely using lifestyle modification, oral contraceptives, insulin sensitizers, and antiandrogens, although a few patients may require further suppression of their hypothalamic-pituitary-ovarian axis with a long-acting gona-dotropin-releasing hormone analog. It is likely that HAIR-AN patients are at greater risk for metabolic dysfunction and diabetes mellitus, although long-term studies are lacking. Finally, the distinction between HAIR-AN and the polycystic ovary syndrome (PCOS) is becoming less clear as more patients with PCOS are being recognized as potentially having postreceptor abnormalities in insulin signaling. Better characterization awaits more detailed phenotyping and genotyping studies.
Lithium therapy and alkaline earth metal metabolism: a biochemical screening study (1977)

A study is described of 90 patients receiving lithium prophylactically for recurrent affective disorder. A total of 90 biochemical variables was analysed by correlation matrices. No abnormality in calcium or magnesium metabolism was detected though this may merely be a reflection of the insensitivity of the screening technique used.
Compressive Phase-space Imaging for 3D Neural Activity Tracking (2016)

This talk will describe new computational methods for 3D imaging in scattering media using phase space (e.g. light field) datasets and sparsity-contrained atomic norm algorithms. Experimentally, we use optogenetic tags to achieve real-time 3D neural activity tracking with high resolution across a large volume.
Des humanités numériques à la Singularité technologique (2017)

Après avoir rappelé ce qu’est la version informatique du trans-humanisme et ses liens à la Singularité technologique, nous développons ici une réflexion sur le futur de l’Humanité, de l’humanisme et des humanités dans le contexte du développement rapide des technologies de l’information. La première partie rappelle les nombreuses annonces publiques qui prédisent une prochaine fin de l’Humanité. Nous analysons ensuite ce que signifie la fin de l’Humanité en distinguant d’abord la fin de l’espèce humaine de la fin de l’existence humaine. La troisième partie étudie la signification d’une fin de l’humanisme, l’humanisme étant compris ici comme une philosophie qui considère que l’être humain est la valeur suprême. La dernière partie traite de la fin des humanités et conclut sur l’émergence d’un humanisme numérique qui donne un nouvel élan aux humanités.
Effect of Surface Charge on the Uptake and Distribution of Gold Nanoparticles in Four Plant Species (2012)

Small (6-10 nm) functionalized gold nanoparticles (AuNPs) featuring different, well-defined surface charges were used to probe the uptake and distribution of nanomaterials in terrestrial plants, including rice, radish, pumpkin, and perennial ryegrass. Exposure of the AuNPs to plant seedlings under hydroponic conditions for a 5-day period was investigated. Results from these studies indicate that AuNP uptake and distribution depend on both nanoparticle surface charge and plant species. The experiments show that positively charged AuNPs are most readily taken up by plant roots, while negatively charged AuNPs are most efficiently translocated into plant shoots (including stems and leaves) from the roots. Radish and ryegrass roots generally accumulated higher amounts of the AuNPs (14-900 ng/mg) than rice and pumpkin roots (7-59 ng/mg). Each of the AuNPs used in this study were found to accumulate to statistically significant extents in rice shoots (1.1-2.9 ng/mg), while none of the AuNPs accumulated in the shoots of radishes and pumpkins.
Thickness shear mode epitaxial (10–12) LiNbO3 (11–20) AZO/(10–12) Al2O3 BAW resonator (2022)

LiNbO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</inf> have been used for the SAW filters because of their high Q and k. However, LiNbO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</inf> films have not used in the BAW industry because thickness extensional mode k <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">t</inf> <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> in the c-axis oriented LiNbO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</inf> films, which can be grown in the standard sputtering process, is significantly low compared with quasi-shear mode k <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">35</inf> <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> in the 168° Ycut LiNbO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</inf> . Therefore, the mechanical thinning of bulk LiNbO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</inf> single crystal plate has been used to fabricate the thin single crystalline layer for BAW resonators. In this study, we demonstrate the epitaxial growth of (10–12) LiNbO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</inf> on epitaxial (11–20) Al doped conductive ZnO layer (AZO)/(10–12) Al <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> O <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</inf> substrate. Thickness shear mode acoustic properties of the resonator were reported.
A linear limiter: a 11-GHz monolithic low distortion variable gain amplifier (2002)

A novel 11-GHz monolithic low-distortion variable gain amplifier is proposed. The amplifier maintains high linearity up to the high input power level using variable negative feedback. The third-order intermodulation distortion ratio of this amplifier is improved by more than 40 dB compared with conventional variable-gain amplifiers under compressed gain conditions.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Arteriogenesis versus angiogenesis in peripheral artery disease (2012)

Different forms of vessel growth in the adult organism contribute to the compensation for an occluded artery. We here summarize the major differences between arteriogenesis and angiogenesis and provide evidence in favour of a therapeutic stimulation of collateral growth. In addition, we outline current knowledge about regulatory mechanisms transducing the initial physical stimulus into a cellular response. As an example, the role of nitric oxide during arteriogenesis is discussed, and finally, we propose a mechanism of how an efficient decision is made that makes the larger collaterals larger and the smaller ones smaller.
Integral Helicopter Cargo Restraint System (1969)

Abstract : This report presents the engineering concepts and preliminary design of an integral helicopter cargo restraint system that may be incorporated in present or future helicopters. Candidate cargo restraint systems and energy absorber concepts were formulated and evaluated both qualitatively and quantitatively to meet crash survivability design objectives. A theoretical analysis of restraint fittings, cargo floor, and fuselage frame of a CH-47 helicopter was conducted to ascertain their compatibility with dynamic loads. The object of this contractual effort was to achieve a more effective cargo restraint system which would limit cargo movement in all directions by energy absorption in order to prevent injuries to crewmen or passengers in a potentially survivable crash.
Temporal distribution of partial seizures: Comparison of an animal model with human partial epilepsy (1998)

Seizures do not often strike randomly but may occur in circadian patterns. We compared daily times of partial seizures determined by continuous electroencephalography among patients with mesial temporal lobe epilepsy (MTLE; n = 64), those with extratemporal lobe (XTLE; n = 26) or lesional temporal lobe epilepsy (LTLE; n = 8), and a rat model similar to MTLE in which rats become epileptic after electrically induced limbic status epilepticus (postlimbic status [PLS]; n = 20). Rats were maintained on a 12-hour light/dark cycle with lights on at 0700 hours. The distributions of seizures were fitted by cosinor analysis to determine time of peak seizure incidence +/- 95% confidence interval (95% CI). The mean fraction +/- SD of seizures recorded during light was 63 +/- 17% in PLS animals and 60 +/- 21% in humans. Peak incidence of seizures for PLS rats (547 seizures) was 1645 (95% CI = 1448,1830) and for MTLE subjects (774 seizures) was 1500 (95% CI = 1324,1636). Seizures from XTLE (465 seizures) and LTLE (48 seizures) did not fit a cosinor model and occurred no more frequently during light than dark. In conclusion, limbic seizures in humans and PLS rats occur more often during light than dark and have similar cosinor daily distributions. The chronological similarity between human MTLE and PLS rat epilepsy suggests that limbic seizure occurrence has a relation to the circadian regulatory system.
Polarization-Based Sensing of Glucose Using an Oriented Reference Film (1999)

We describe a new approach to glucose sensing using polarization measurements in the presence of a stretch-oriented reference film. The method relies on measurement of the polarized emission from the reference film and of a fluorophore which changes intensity in response to glucose. A glucose-sensitive fluorescent signal was provided by the glucose/galactose binding protein from E. coli. This protein was labeled with an environmentally sensitive fluorophore at a single genetically inserted cysteine residue, and displayed decreased fluorescence upon glucose binding. Using the protein and the reference film we observed glucose-sensitive polarization values for micromolar glucose concentrations. This method of polarization-based sensing is generic and can be used for any sensing fluorophore which displays a change in intensity. In principle, one can construct simple and economical devices for this type of glucose measurement. © 1999 Society of Photo-Optical Instrumentation Engineers.
Supplementary Figure S1 from Methionine Deprivation Induces a Targetable Vulnerability in Triple-Negative Breast Cancer Cells by Enhancing TRAIL Receptor-2 Expression (2023)

&lt;p&gt;Supplementary Figure S1. Methionine restriction inhibits cell proliferation.&lt;/p&gt;
Design, synthesis and antioxidant properties of ovothiol-derived 4-mercaptoimidazoles (1997)

Fourteen 4-mercaptoimidazoles derived from the naturally occurring family of antioxidants, the ovothiols, have been synthesized by cyclization of thioamides with trimethylsilyl trifluoromethanesulfonate (triflate). These compounds have been assayed for their radical-scavenging activity.
Mechanisms of generation and suppression of oscillations in the basal ganglia (2011)

Frontiers Events is a rapidly growing calendar management system dedicated to the scheduling of academic events. This includes announcements and invitations, participant listings and search functionality, abstract handling and publication, related events and post-event exchanges. Whether an organizer or participant, make your event a Frontiers Event!
Clinical Evaluation of Catheter-Related Fungemia and Bacteremia. (1995)

Forty-four patients with catheter-related infection admitted to Hokusho Central Hospital between 1985 and 1991 were studied retrospectively. The rate of catheter-related fungemia or bacteremia to all corresponding cases of fungemia and bacteremia increased from 7.7% in 1985 to 28.8% in 1991. The isolated pathogens were Candida parapsilosis (8 strains), Candida tropicalis (6 strains), methicillin-resistant Staphylococcus aureus (MRSA) (6 strains), methicillin-sensitive S. aureus (MSSA) (5 strains) and Streptococcus epidermidis (3 strains). Bacteremia occurred after catheterization of the femoral vein for a mean duration of 37 days. The period was significantly shorter than that after catheterization of the subclavian vein (56 days). The major isolates from the subclavian vein were Candida spp. (14/17, 82.4%), followed by MRSA (1/17, 5.9%) and MSSA (1/17, 5.9%), while isolates from the femoral vein were Candida spp. (6/16, 37.5%), MRSA (5/16, 31.3%) and MSSA (3/16, 20.8%). Catheter removal alone did not improve the clinical condition, particularly in MRSA bacteremia; the combination of antimicrobial therapy and removal of the catheter was necessary for a better prognosis.
Temperature characteristics of solidly mounted piezoelectric thin film resonators (2004)

Solidly mounted piezoelectric thin film resonators (SMRs), which are consisting of a piezoelectric film on alternating laminated low- and high-acoustic-impedance quarter-wave layers on a substrate, are now receiving attention as bulk acoustic wave devices suitable for use in a super-high-frequency range. For practical applications, the temperature dependence of frequency is desirable to be very low. This paper reports the theoretical analysis on the temperature characteristics of the SMR using zinc oxide (ZnO) as the piezoelectric material, silicon dioxide (SiO/sub 2/) as the low impedance material, and ZnO as the high impedance material. The calculated results show that the temperature coefficient of frequency (TFC) varies from -60 ppm//spl deg/C to -27 ppm//spl deg/C with increasing the total layer number. This improvement of TCF results from the positive TCF of SiO/sub 2/. It is also shown that the temperature compensation of the SMR can be achieved by increasing the thickness of the first /spl lambda//4 SiO/sub 2/ layer just below the piezoelectric film or by depositing a thin SiO/sub 2/ capping layer on the piezoelectric film, although the effective electromechanical coupling factor K/sup 2/ and the electric Q decrease a little. Similar theoretical analysis has been performed on the SMRs using ZnO or aluminum nitride (AlN) as the piezoelectric material, molybdenum (Mo) or aluminum nitride (AlN) as the high impedance material, and SiO/sub 2/ as the low impedance material.
Heterogeneous colorimetric sensor for mercuric saltsElectronic supplementary information (ESI) available: Materials and methods. See http://www.rsc.org/suppdata/cc/b3/b314138a/ (2004)

A novel chemical sensor for the colorimetric detection of mercuric salts is described. The sensor is based on a mesoporous nanocrystalline TiO2 film sensitised with a ruthenium dye; immersion of this film in an aqueous solution of Hg2+ results in a rapid colorimetric response, with both a high selectivity and a sub-micromolar sensitivity.
Hierarchical Porous Polymer Scaffolds from Block Copolymers (2013)

Hierarchical porous polymer materials are of increasing importance because of their potential application in catalysis, separation technology, or bioengineering. Examples for their synthesis exist, but there is a need for a facile yet versatile conceptual approach to such hierarchical scaffolds and quantitative characterization of their nonperiodic pore systems. Here, we introduce a synthesis method combining well-established concepts of macroscale spinodal decomposition and nanoscale block copolymer self-assembly with porosity formation on both length scales via rinsing with protic solvents. We used scanning electron microscopy, small-angle x-ray scattering, transmission electron tomography, and nanoscale x-ray computed tomography for quantitative pore-structure characterization. The method was demonstrated for AB- and ABC-type block copolymers, and resulting materials were used as scaffolds for calcite crystal growth.
A Growing World of Small Things: A Brief Review On the Nanostructured Vaccines (2017)

Vaccines are the most cost-effective intervention in the management of infectious disease. Much of what we perceive as quality of life is related to a good health status and disease absence, for which vaccines are substantially responsible. Nonetheless, there are many infectious diseases for which no vaccine solution is available. That could be due to limitations of the classic approaches to vaccine development, including inactivated, subunit and attenuated vaccines. Nanostructured immunogens belong to a class of nonclassic vaccines in which nanostructures are loaded with antigen-related molecules. Here, we briefly review important features of the nanostructured vaccines – mainly those based in carbon nanotubes and gold nanorods – and discuss their use to prevent infectious diseases, especially those caused by viruses.
Human Secretory Immune Response to Fatty Acid-Binding Protein Fraction from Giardia lamblia (2002)

The secretory immune response in humans infected with Giardia lamblia was studied by using saliva samples and an 8-kDa antigen capable of binding fatty acids. This antigen was not recognized by saliva samples from healthy individuals. The antigen may be useful in diagnostic studies of G. lamblia infection.
The Examination of Extreme Flood Events and Resiliency in the Middle St. Johns River, Florida USA Via Multiple Methods (2020)

The middle portion of the St. Johns River is located in East-Central Florida, USA. This region of the St. Johns River is increasingly subject to urbanization and conversion of forest areas to agricultural land. Overall, these changes mean that future flood events in the area could adversely impact local citizens. Therefore, the examination of extreme flood events and resiliency to such events is critically important. The purpose of this preliminary study is to explore a range of practical applications to estimate extreme flood events at locations within the Middle St. Johns River Basin, focusing specifically upon the Wekiva River sub-basin (located just west of Lake Mary, Florida). The current work illustrates the overall technical methodology and provides preliminary estimates of extreme flood events at different return frequencies using two statistical approaches. Future work will also estimate the magnitude of extreme flood events via model simulations utilizing an existing Wekiva River HSPF rainfall-runoff model previously developed by the Saint Johns River Water Management District. Altogether, once fully integrated and complete, the methods will permit prediction of a range of possible flood discharges at any place along the Wekiva watercourse.
Joint optimization of idle and cooling power in data centers while maintaining response time (2010)

Server power and cooling power amount to a significant fraction of modern data centers' recurring costs. While data centers provision enough servers to guarantee response times under the maximum loading, data centers operate under much less loading most of the times (e.g., 30-70% of the maximum loading). Previous server-power proposals exploit this under-utilization to reduce the server idle power by keeping active only as many servers as necessary and putting the rest into low-power standby modes. However, these proposals incur higher cooling power due to hot spots created by concentrating the data center loading on fewer active servers, or degrade response times due to standby-to-active transition delays, or both. Other proposals optimize the cooling power but incur considerable idle power. To address the first issue of power, we propose PowerTrade, which trades-off idle power and cooling power for each other, thereby reducing the total power. To address the second issue of response time, we propose SurgeGuard to overprovision the number of active servers beyond that needed by the current loading so as to absorb future increases in the loading. SurgeGuard is a two-tier scheme which uses well-known over-provisioning at coarse time granularities (e.g., one hour) to absorb the common, smooth increases in the loading, and a novel fine-grain replenishment of the over-provisioned reserves at fine time granularities (e.g., five minutes) to handle the uncommon, abrupt loading surges. Using real-world traces, we show that combining PowerTrade and SurgeGuard reduces total power by 30% compared to previous low-power schemes while maintaining response times within 1.7%.