gebhart/patrepeval huggingface dataset:
Research of security metric architecture for Next Generation Network (2009)

Constructing a security metric architecture in next generation network is a critical part for network security assessment. In this paper, a three-dimensional security metric architecture model is given. In this model, four comprehensive metrics, which are vulnerability, threat, stability and survivability, are first presented. Then based on these four metrics, a hierarchical security metric architecture is devised, and instanced in a prototype system of NGN. Compared with qualitative metrics, the presented metrics are not only accurate, but also measurable and easy to collect based on the quantitative parameters. Since there is limited research result of the security metric architecture for NGN at present, this model can be referenced to a certain extent.
Stereotaxic Needle Localization and Cytological Diagnosis of Occult Breast Lesions (1986)

A stereotaxic technique for localization of occult breast lesions and fine needle aspiration for cytological diagnosis was used on examination of 543 patients. Successful localization with the needle tip within 1 mm of the suspected lesion was possible in 490 patients (90.2%). Based on a high mammographic index of suspicion for malignancy, 187 of 490 patients were selected to undergo open biopsy, following aspiration cytology and localization with methylene blue injection. The statistical results (cytologic vs. histologic examination) revealed a sensitivity of 97.5% and a specificity of 95.2% for cytologic diagnosis of occult breast lesions. The technique is easy to learn and takes 20-30 minutes to perform. Compliance was 100% and complications were nil. This new technique expedites localization and maximizes the specificity of mammography for occult breast lesions.
GaAs Mixed Signal Multi-Function X-Band MMIC with 7 Bit Phase and Amplitude Control and Integrated Serial to Parallel Converter (2000)

The design and measured performance of a GaAs multi-function X-band MMIC for space-based synthetic aperture radar (SAR) applications with 7-bit phase and amplitude control and integrated serial to parallel converter (including level conversion) is presented. The main application for the multi-function chip (MFC) is to provide full amplitude and phase control in the transmit path and the receive path of T/R modules. The MFC has been realised in the OMMIC ED02AH 0.2 μm PHEMT process providing enhancement and depletion FET's.
Velvetbean for the Management of Root-Knot and Southern Blight in Peanut (1992)

The value of Florida velvetbean (Mucuna deeringiana) as a rotation crop for the management of root-knot nematode (Meloidogyne arenaria) and southern blight (Sclerotium rolfsii) in 'Florunner' peanut (Arachis hypogaea) was studied from 1989-1991 in a field experiment in southeastern Alabama. The field had been in peanut with winter fallow for the preceeding 10 years and was heavily infested with M. arenaria. In 1991, the yield of peanut following 2 years of velvetbean (V-V-P) was 47% higher than the yield of monoculture peanut without nematicide [P(-)] and 20% higher than that of monoculture with aldicarb [P(+)] applied at-plant (0.302 g a.i./m row in a 20-cm band). Compared with peanut plots, plots with velvetbean in 1989 and 1990 had low populations of M. arenaria juveniles in soil at peanut harvest. In 1991, M. arenaria juvenile populations in soil were lowest in plots with the V-V-P rotation and highest in those with P(-); numbers of juveniles in plots with P(+) were lower than in
Peripheral Nerve Impairment in a Mouse Model of Alzheimer’s Disease (2021)

Sarcopenia, a geriatric syndrome involving loss of muscle mass and strength, is often associated with the early phases of Alzheimer's disease (AD). Pathological hallmarks of AD including amyloid β (Aβ) aggregates which can be found in peripheral tissues such as skeletal muscle. However, not much is currently known about their possible involvement in sarcopenia. We investigated neuronal innervation in skeletal muscle of Tg2576 mice, a genetic model for Aβ accumulation. We examined cholinergic innervation of skeletal muscle in adult Tg2576 and wild type mice by immunofluorescence labeling of tibialis anterior (TA) muscle sections using antibodies raised against neurofilament light chain (NFL) and acetylcholine (ACh) synthesizing enzyme choline acetyltransferase (ChAT). Combining this histological approach with real time quantification of mRNA levels of nicotinic acetylcholine receptors, we demonstrated that in the TA of Tg2576 mice, neuronal innervation is significantly reduced and synaptic area is smaller and displays less ChAT content when compared to wild type mice. Our study provides the first evidence of reduced cholinergic innervation of skeletal muscle in a mouse model of Aβ accumulation. This evidence sustains the possibility that sarcopenia in AD originates from Aβ-mediated cholinergic loss.
Advancing a vaccine to prevent human schistosomiasis (2016)

Several candidate human schistosomiasis vaccines are in different stages of preclinical and clinical development. The major targets are Schistosoma haematobium (urogenitial schistosomiasis) and Schistosoma mansoni (intestinal schistosomiasis) that account for 99% of the world's 252 million cases, with 90% of these cases in Africa. Two recombinant S. mansoni vaccines - Sm-TSP-2 and Sm-14 are in Phase 1 trials, while Smp80 (calpain) is undergoing testing in non-human primates. Sh28GST, also known as Bilhvax is in advanced clinical development for S. haematobium infection. The possibility remains that some of these vaccines may cross-react to target both schistosome species. These vaccines were selected on the basis of their protective immunity in preclinical challenge models, through human immune-epidemiological studies or both. They are being advanced through a combination of academic research institutions, non-profit vaccine product development partnerships, biotechnology companies, and developing country vaccine manufacturers. In addition, new schistosome candidate vaccines are being identified through bioinformatics, OMICs approaches, and moderate throughput screening, although the full potential of reverse vaccinology for schistosomiasis has not yet been realized. The target product profiles of these vaccines vary but many focus on vaccinating children, in some cases following mass treatment with praziquantel, also known as vaccine-linked chemotherapy. Several regulatory pathways have been proposed, some of which rely on World Health Organization prequalification.
LT-1 Baseline Calibration Method Based on Improved Baseline Calibration Model (2022)

Interferometric synthetic aperture radar (InSAR) is an effective digital elevation model (DEM) generation tool. High-precision InSAR DEM requires an accurate baseline. The baseline accuracy can reach 2 mm in the TanDEM-X mission. However, compared with the X-band, the L-band has the characteristics of long wavelength, strong penetrability, and low backscattering coefficient, which leads to the elevation error caused by the penetration depth and the signal-to-noise ratio (SNR) decorrelation cannot be ignored. Therefore, this paper proposes a baseline calibration method with compensation for additional height error caused by penetration depth and SNR decorrelation. Aiming at the baseline calibration of L-band InSAR TwinSAR-L (LT-1), this paper calculates the calibration accuracy of proposed calibration method by using Advanced Land Observing Satellite-2 (ALOS-2) data when taking desert as the calibration field. The results show that the baseline error before additional elevation error compensation is <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$2.6 \text{mm} (1\delta)$</tex> , and reduces to <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$0.85 \text{mm}(1\delta)$</tex> after compensation. Therefore, the baseline calibration method in this paper can effectively realize the baseline calibration of LT-1.
904 The measurement of TVF with small aspect ratio(2) (2007)

In this study, our purpose is to obtain instantaneous and mean velocity profiles in a Taylor-couette vortex flow(TVF) by using a UTDC device based on a ultrasonic generator. The experiment was carried out with a small aspect ratio where the Ekman boundary layer was not neglected. The device has a radial ratio of 0.375, aspect ratio of 3 and the gap length between the inner and outer cylinders of 25mm. As the result, the velocity profiles and their absolute values were in good agreement with those obtained by the Ultrasonic velocity profiler (UVP). This measurement system was applied to the solid-liquid phase flow experimentally, and well measured even in the opaque dilute solution.
Monolayer of physically separated fept islands with a tetragonal L1/sub 0/ structure produced by thermally created mass transport (2003)

A monolayer of physically separated FePt islands has been produced by thermally created mass transport of ultrathin FePt film, whereby formation of a magnetic layer composed of a two-dimensional arrangement of physically separated magnetic grains for decrease of magnetic coupling between the grains can be realized. The monolayer with [001] orientation was produced on [100] oriented MgO film. The produced monolayer had a small and uniform grain size and tetragonal L1/sub 0/ structure. Formation of granular film composed of a three-dimensional arrangement of L1/sub 0/-FePt ordered grains with [001] orientation in MgO film has been achieved by stacking the monolayer of FePt islands with MgO separation layers for high-density perpendicular media.
A Correlation Analysis on the Depth and Breadth of ESL Learners’ Vocabulary Knowledge and Their Overall Linguistic Competence (2014)

The breadth and depth of ESL learners' vocabulary knowledge and their comprehensive linguistic competence are not well studied in current literatures on vocabulary studies. This paper explores the creditability of depth and breadth of ESL learners' vocabulary knowledge as an indicator of their overall linguistic competence and the correlation between depth and breadth of ESL learners' vocabulary knowledge. The results show that both the depth and breadth of ESL learners' vocabulary knowledge can effectively be representative of their linguistic competence, of which the depth of ESL learners' vocabulary knowledge is better than the breadth of their vocabulary knowledge as an indicator of their overall linguistic competence. In general, the breadth of ESL learners' vocabulary knowledge is highly positively correlated with the depth of their vocabulary knowledge but the development of depth of vocabulary knowledge still lags behind the development of breadth of vocabulary knowledge.
Hepatitis C--new developments in the studies of the viral life cycle. (2007)

Hepatitis C virus (HCV) is a causative agent of chronic liver disease leading to cirrhosis, liver failure and hepatocellular carcinoma. The prevalence of HCV is estimated as 3% of the world population and the virus is a major public health problem all over the world. For over 16 years, since HCV had been discovered, studies of the mechanisms of the viral life cycle and virus-host interactions have been hampered by the lack of a cell culture system allowing the virus to be grown in laboratory conditions. However, in recent years some new model systems to study HCV have been developed. The major breakthrough of the last two years was the cell culture system for maintaining the virus in an adapted hepatocyte-derived cell line. This review describes the techniques and applications of most of the in vitro systems and animal models currently used for working with hepatitis C virus.
Amidine Derivatives of Avibactam: Synthesis and In Vitro β‐Lactamase Inhibition Activity (2021)

Abstract Avibactam is a non‐β‐lactam based second generation β‐lactamase inhibitor containing diazabicyclooctane (DBO) ring as the β‐lactam mimic. We substituted C2 position of DBO scaffold by a number of amidine derivatives to form water soluble final compounds A1 ‐ A14 . The synthesized compounds were evaluated for their antibacterial and synergistic activity in combination with an antibiotic in vitro . The compounds, were tested against ten bacterial strains alone and in combination with existing antibiotic, meropenem. All compounds didn't show antibacterial activity when alone (MIC,&gt;128 μM), however exhibited moderate to good synergistic activity in the presence of meropenem by lowering its MIC values. Compound A7 proved the most potent among other counterparts against all bacterial species with MIC from &lt;0.29 μM to 2.34 μM, and showed comparable or improved activity to avibactam against eight bacterial strains. Compound A7 may prove a lead for next level in vivo and clinical studies.
High-dynamic-range front end for automatic image processing applications (1998)

A camera system is described which can be used as a front end to automatic image processing applications, capable of imaging very high dynamic range scenes. We were inspired by the mammalian retina to build a system entirely upon commercially-available components which has the maximum flexibility and minimum risk and development cost. The result is a system which includes logarithmic photodetectors, together with simple robust fixed pattern noise correction and high-pass spatial filtering.
Semiconducting Tellurium−Iron−Copper Carbonyl Polymers (2008)

The unprecedented ternary Te-Fe-Cu chain polymers [{Et4N}{TeFe3(CO)9Cu}]infinity and [{TeFe3(CO)9Cu2}(mu-4,4'-dipyridyl)1.5]infinity were prepared from the self-assembly of [Et4N]2[TeFe3(CO)9] with [Cu(MeCN)4][BF4] in THF or in the presence of 4,4'-dipyridyl in THF. These two chain polymers, which can also be constructed from the precursor complex TeFe3(CO)9Cu2(MeCN)2, show semiconducting behaviors with low band gaps of 0.59 and 0.41 eV, respectively. In addition, their conductivity and the effect of the bridging ligand are further elucidated by theoretical calculations.
A Micropower CMOS-Instrumentation Amplifier (1985)

A CMOS switched capacitor instrumentation amplifier is presented. Offset is reduced by an auto-zero technique and effects due to charge injection are attenuated by a special amplifier configuration. The circuit which is realized in a 4-/spl mu/m double poly process has an offset (/spl tau/) of 370 /spl mu/V, an rms input referred integrated noise (0.5 -f/sub c//2) of 79 /spl mu/V, and consumes only 21 /spl mu/W (f/sub c/ = 8 kHz, V/sub DD/ = 3 V).
Experimental Demonstration of a Cost-Effective Broadcast Overlay for a Commercial WDM PON (2011)

We demonstrate a simple cost-effective broadcast overlay for WDM PON which uses a single directly modulated superluminescent diode to deliver an RF video or baseband gigabit-Ethernet service to all 32 users.
Monitoring the ambient environment with diffusive samplers: theory and practical considerations (2000)

The first page of this article is displayed as the abstract.
Smoking withdrawal shifts the spatiotemporal dynamics of neurocognition (2010)

Smoking withdrawal is associated with significant deficits in the ability to initiate and maintain attention for extended periods of time (i.e. sustained attention; SA). However, the effects of smoking abstinence on the temporal dynamics of neurocognition during SA have not been evaluated. Twenty adult smokers underwent functional magnetic resonance imaging scans following smoking as usual and after 24-hours abstinence. During scanning they completed a SA task with two levels of task difficulty, designed to measure both sustained (i.e. over the duration of the task) and transient (i.e. event-related) activation. Smoking abstinence significantly decreased task accuracy regardless of task difficulty. Compared to smoking as usual, abstinence resulted in decreased sustained activation in right inferior and middle frontal gyri but increased transient activation across dispersed cortical areas including precuneus and right superior frontal gyrus. Greater task difficulty was associated with even greater transient activation during abstinence in mostly right hemisphere regions including right inferior frontal gyrus. These findings suggest smoking withdrawal shifts the temporal and spatial dynamics of neurocognition from sustained, right prefrontal activation reflecting proactive cognitive control (Braver, Gray & Burgess 2009) to more dispersed and transient activation reflecting reactive control.
Generation and characterization of plasma channels in gas puff targets using soft X-ray radiography technique (2014)

We present our recent results of a formation and characterization of plasma channels in elongated krypton and xenon gas puff targets. The study of their formation and temporal expansion was carried out using a combination of a soft X-ray radiography (shadowgraphy) and pinhole camera imaging. Two high-energy short laser pulses were used to produce the channels. When a pumping laser pulse was shaped into a line focus, using cylindrical and spherical lenses, the channels were not produced because much smaller energy density was deposited in the gas puff target. However, when a point focus was obtained, using just a spherical lens, the plasma channels appeared. The channels were up to 9 mm in length, had a quite uniform density profile, and expanded in time with velocities of about 2 cm/μs.
Antimigraine action of nicotine: theoretical basis and potential clinical application (2007)

Dubai Police Medical Services, Dubai, United Arab Emirates Correspondence to Dr Vinod Kumar Gupta, MB, BS, MD, Physician, Dubai Police Medical Services, PO Box 12005 Dubai, United Arab Emirates Tel/fax: +971 4 3355954; e-mail: [email protected] Ethical adherence: informed consent was taken from the patient. Received 2 October 2006 Accepted 20 January 2007
Augmentation of interleukin-2 production and delayed hypersensitivity in mice infected with Mycobacterium bovis and fed a diet supplemented with vitamin A acetate (1985)

High-dose Mycobacterium bovis-infected mice fed a vitamin A acetate-supplemented diet developed a positive skin reaction to purified protein derivative of mycobacteria, and their spleen cells showed an increased IL-2 production in vitro.
The effect of chemotherapy on expression of folate receptor-alpha in ovarian cancer (2011)

FR-α was expressed in the majority of serous ovarian tumors, although >50% of cases showed only weak expression. Chemotherapy did not alter expression rates in remaining vital tumor tissue, indicating that folate-targeted agents may have a place in the treatment for ovarian cancer, before as well as after chemotherapy. Furthermore, FR-α status did not influence survival.
Melanoma Immunotherapy: Next-Generation Biomarkers (2018)

The recent emergence of cancer immunotherapies initiated a significant shift in the clinical management of metastatic melanoma. Prior to 2011, melanoma patients only had palliative treatment solutions which offered little to no survival benefit. In 2018, with immunotherapy, melanoma patients can now contemplate durable or even complete remission. Treatment with novel immune checkpoint inhibitors, anti-cytotoxic T-lymphocyte protein 4 and anti-programmed cell death protein 1, clearly result in superior median and long-term survivals compared to standard chemotherapy; however, more than half of the patients do not respond to immune checkpoint blockade. Currently, clinicians do not have any effective way to stratify melanoma patients for immunotherapies. Research is now focusing on identifying biomarkers which could predict a patient's response prior treatment initiation (or very early during treatment course), in order to maximize therapeutic efficacy, avoid unnecessary costs, and undesirable heavy side effects for the patient. Given the rapid developments in this field and the translational potential for some of the biomarkers, we will summarize the current state of biomarker research for immunotherapy in melanoma, with an emphasis on omics technologies such as next-generation sequencing and mass cytometry (CyTOF).
A Linear Servo Amplifier for Remote Control Applications (1977)

This paper describes a newly developed Servo amplifier and pulse width demodulator.* The integrated circuit is designed primarily for application in digital proportional radio control systems, but can serve in other closed or open loop control applications.
Efficacy of Controlled‐Release Subgingival Chlorhexidine to Enhance Periodontal Regeneration (2003)

These pilot results indicate that locally delivered, controlled-release antimicrobial treatment may improve the amount of bone gain during guided tissue regeneration procedures. These data support the evidence that infection control is an important variable in successful regeneration.
Contact-force rebound, but not its absolute value, may enable differentiation between steam pops with and without cardiac perforation (2013)

Purpose: During radiofrequency ablation (RFA), the ability to know instantly whether a steam pop has led to cardiac perforation (CP) will be of profound clinical significance. Using a new RFA catheter that detects contact forces (CFs), we assessed whether specific CF characteristics can enable the operator to determine whether a steam pop during RFA in the left atrium (LA) has resulted in CP.
Predictors of fracture risk in patients with systemic lupus erythematosus (2018)

Objectives Bone loss in systemic lupus erythematosus is multifactorial. Recent studies demonstrate corticosteroids, previous fractures and increasing age decrease bone mineral density. The effect of body mass index and fat mass are less well characterized. We sought to determine fracture risk factors in patients undergoing dual-energy X-ray absorptiometry scanning at a district hospital in 2004-2015. Methods Standard dual-energy X-ray absorptiometry parameters were recorded, plus rheumatoid arthritis diagnosis, smoking status, alcohol consumption, family history of fractures, history of secondary operation and corticosteroid use. Data were analyzed using Fisher's exact test for categorical data and logistic regression for continuous data. Results One hundred and fifty patients (141 women, nine men) with SLE were included; 52 (34.6%) had sustained at least one fracture. Fracture risk increased with increased age, body mass index, fat mass and average tissue thickness, and decreased lean mass (adjusted for steroid use), as well as with smoking and rheumatoid arthritis. Increased femoral and vertebral bone mineral density conversely decreased fracture risk. Conclusion Our study suggests increased age, body mass index, fat mass, smoking and/or rheumatoid arthritis increase fracture risk in SLE patients. To our knowledge, this is the first demonstration of a correlation between increased fat mass, adjusted for steroid use and fracture risk, in adults, potentially indicating a differential effect of fat on bone metabolism and lessening of lean body mass.