gebhart/patrepeval huggingface dataset:
Development of Electricity Pricing Criteria at Residential Community Level (2014)

In the UK there is no real time retail market, and hence no real time retail electricity pricing. Therefore domestic electricity consumers in the UK pay electricity prices that do not vary from hour to hour, but are rather some kind of average price. Real time pricing information was identified as a barrier to understanding the effectiveness of various incentives and interventions. The key question is whether we can evaluate energy management and renewable energy intervention in the behaviour of customers in real market terms. Currently only behaviour changes with respect to total consumption can be evaluated. Interventions cannot be defined for peak load behaviour. The effectiveness of the introduction of renewable energy is also hard to assess. Therefore, it is hard to justify introducing of renewable and demand side management at local community level, apart from when following government approved schemes, subsidies, and other initiatives. In this paper, a new criteria has been developed to help developers and planners of local residential communities to understand the cost of intervention, in order to evaluate where the load is when the prices are high.
Modeling of a piezoelectric transducer and its application to full waveform acoustic logging (1994)

A velocity-stress finite-difference (VS-FD) model is presented for a cylindrical piezoelectric transducer in a borehole. The borehole may be irregular and the surrounding formation inhomogeneous. The model is two dimensional in that azimuthal symmetry is assumed. The description of the tranducer is a full elasto-electromagnetic one, including transverse isotropy in the elastic, dielectric, and piezoelectric parameters, and dissipation in the piezoelectric material. The borehole propagation portion of the model is verified by comparison with a standard transform technique. Predictions of the model for a piezoelectric cylinder radiating into a fluid medium are compared to experimental results with excellent agreement. The radiation patterns of a bare transducer near resonance frequencies are found to be anisotropic. Acoustic waveforms in a borehole excited by a finite sized cylindrical transducer are displayed and are quite different from those excited by an ideal point pressure source. The effect of borehole loading upon the impedance of the transducer is shown to be small.
Management of non-small cell lung cancer harboring epidermal growth factor receptor mutations in the era of first-line osimertinib (2019)

Osimertinib (AZD9291, Tagrisso™), a third-generation irreversible epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), has brought about rapid transformative changes to the treatment of EGFR-mutation-positive advanced non-small cell lung cancer (NSCLC). After acquiring resistance to first- or second-generation EGFR-TKIs, osimertinib showed greater efficacy than the combination of pemetrexed and platinum-based chemotherapy in patients with the exon 20 T790M resistance mutation in the AURA3 trial (1).
Macrospin model of incubation delay due to the field-like spin transfer torque (2008)

We show that the absence of pre-switching oscillations ("incubation delay") in magnetic tunnel junctions can be explained within the macrospin model by a sizable field-like component of the spin-transfer torque. It is further suggested that measurements of the voltage dependence of tunnel junction switching time in the presence of external easy axis magnetic fields can be used to determine the magnitude and voltage dependence of the field-like torque.
Touch panel with integrated fingerprint sensors based user identity management (2013)

In this paper, to enhance identity acquisition procedures in smartphones and make the process transparent to the user, a novel User Identity Sensing approach leveraging the unified fingerprint enabled touch panel that combines multiple capacitive TFT based fingerprint sensors directly with the touch screen panel of the smartphone is proposed. The solution passively fulfills mobile users identity management during natural user-device touch interactions and requires neither password nor extra actions from the user, which makes it highly user friendly. To demonstrate the feasibility of such a unified, user identity sensing based design, an investigation of the hardware metrics is performed. Simulation experiments are conducted to evaluate the system with touch data collected from 25 smartphone users. The resulting observations and simulation results provide guidance for an efficient design of the hardware and criteria that need to be satisfied for the development of an operational prototype.
A new surface-antigen-adsorbed influenza virus vaccine II. Studies in a volunteer group (1975)

A group of 23 volunteers were each inoculated with 600 CCA of a new form of influenza virus A/England/42/72 vaccine; this vaccine consisted of purified haemagglutinin and neuraminidase antigens adsorbed to alhydrogel. No significant reactions to the vaccine were reported. Twenty-two volunteers produced increased titres of serum HI antibody, and all showed increased titres of NI antibody after immunization. Thus, for volunteers with no pre-immunization serum HI antibody, the geometric mean titre of serum antibody increased from 1/5 to 1/196 after immunization. Ten volunteers developed local neutralizing antibody after immunization; this antibody response was detected most frequently in volunteers who showed the greater serum antibody response to immunization, and in nasal washings with the higher concentrations of protein and IgA. Ten weeks after immunization, the vaccinees and a group of matched controls were inoculated intranasally with attenuated A/England/42/72 virus. Evidence of infection with the challenge virus was found in 14 of the control subjects and in one of the vaccinees. The results indicate that the surface-antigen-adsorbed vaccine induced high titres of serum antibody, and gave significant protection against challenge infection.
V<sc>is</sc>T<sc>iles</sc>: Coordinating and Combining Co-located Mobile Devices for Visual Data Exploration (2017)

We present VISTILES, a conceptual framework that uses a set of mobile devices to distribute and coordinate visualization views for the exploration of multivariate data. In contrast to desktop-based interfaces for information visualization, mobile devices offer the potential to provide a dynamic and user-defined interface supporting co-located collaborative data exploration with different individual workflows. As part of our framework, we contribute concepts that enable users to interact with coordinated & multiple views (CMV) that are distributed across several mobile devices. The major components of the framework are: (i) dynamic and flexible layouts for CMV focusing on the distribution of views and (ii) an interaction concept for smart adaptations and combinations of visualizations utilizing explicit side-by-side arrangements of devices. As a result, users can benefit from the possibility to combine devices and organize them in meaningful spatial layouts. Furthermore, we present a web-based prototype implementation as a specific instance of our concepts. This implementation provides a practical application case enabling users to explore a multivariate data collection. We also illustrate the design process including feedback from a preliminary user study, which informed the design of both the concepts and the final prototype.
Updates to the Canadian Immunization Guide: April 2015 to October 2016 (2016)

The <i>Canadian Immunization Guide</i> (CIG) is a trusted, reader-friendly summary of information and advice on immunization that has been used by health care providers and policy makers for decades. It is continuously updated based on new recommendations from the National Advisory Committee on Immunization (NACI) and the Committee to Advise on Tropical Medicine and Travel (CATMAT), two external advisory bodies to the Public Health Agency of Canada. In September 2016, the CIG moved to a new web platform that has improved navigability and is more mobile friendly. Between April 2015 and October 2016, five new NACI statements were published and are reflected in the CIG. The objective of this article is to provide readers with highlights of recent key changes to active vaccine recommendations in the CIG. For example, for Hepatitis (HA) vaccine, it may now be administered to persons six months of age and older and considered for all individuals receiving repeated replacement of plasma-derived clotting factors. There are now new recommendations for the use of HA immunoglobulin post-exposure prophylaxis. For Human papillomavirus (HPV) vaccine, any of the authorized HPV vaccines in Canada, including HPV9 vaccine, can be used according to the recommended HPV immunization schedules. For influenza vaccine, adults with neurologic or neurodevelopment conditions have been added to the group for whom influenza vaccination is particularly recommended, high-dose influenza vaccine has been approved for use in Canada in adults ≥65 years of age and live attenuated influenza vaccine (LAIV) is no longer a preferentially recommended product for use in children and adolescents. On an individual basis, pneumococcal conjugate 13-valent (PNEU-C-13) vaccine may be recommended to immunocompetent adults aged 65 years and older if not previously immunized against pneumococcal disease. When it is given, it should precede the pneumococcal polysaccharide 23-valent (PNEU-P-23) vaccine. Varicella immune globulin may now be administered up to 10 days since last exposure for the purpose of disease attenuation and there were a number of minor changes to the criteria for assessing varicella immunity.
Etude des couches ultra minces de sio#2 sur silicium par simulation a l'echelle atomique (1998)

Ce memoire concerne l'etude de la structure des couches ultra minces de dioxyde de silicium sur silicium par la simulation a l'echelle atomique. Dans ce but, il est presente une synthese des modeles d'oxydation du silicium. Il est mis en evidence les limites et faiblesses de la modelisation continue, et la necessite d'introduire la simulation a l'echelle atomique pour aider a mieux comprendre le mecanisme de formation des couches ultra minces. Differents modeles ont a cet effet ete introduits. Le modele des potentiels multicorps, choisi pour faire cette etude, est ainsi decrit, puis valide sur la base des caracteristiques physiques et geometriques du silicium et de l'oxyde de silicium. Une autre approche de validation a concerne la comparaison des sites preferentiels d'energie minimale de l'oxygene sur une surface si(001) trouves par la methode ab initio, via les equation de konh-sham, et la methode des potentiels multicorps. Cette derniere s'est averee etre une bonne approximation de la methode ab initio, vue par la theorie de la fonctionnelle de densite. Il a alors ete discute de l'opportunite et de l'interet de coupler les deux approches. La methode des potentiels multicorps est par la suite appliquee a l'investigation sur la structure cristalline de l'oxyde natif sur silicium, les rugosite et distribution des contraintes a l'interface si/sio#2, et finalement a l'etude de l'influence de la densite des lacunes sur la contrainte et la rugosite dans la region d'interface.
Stochastic Aspects of Granular Flow in Vibrated Beds (2002)

A stochastic approach has been taken to examine the flow behaviour of particles in a vibrated granular bed. The coordinates of a single grain were determined as a function of time using the technique of positron emission particle tracking. Following a particle for extended periods allowed a detailed representation of the displacement probability density to be built up. This showed that, initially, particles dispersed according to a Gaussian law, but that the variation in the solid fraction of grains, their granular temperature and the presence of walls meant that significant distortions were observed over longer timescales. The determination of the displacement probability density allowed the spatial distribution of the granular temperature and the diffusion coefficient to be measured in both mono- and bi-disperse granular systems.
Effects of extrinsic rearfoot posting in custom foot orthoses on frontal plane kinematics and kinetics (2012)

Background A regularly prescribed design variable in foot orthoses (FOs) is the addition of an extrinsic rearfoot post, a feature which can be angled medially or laterally and is intended to control movement of the calcaneus during the stance phase of gait [1]. This study aims to investigate whether introducing incremental changes in this feature will produce a linear trend in the user’s frontal plane biomechanical responses, and whether responses vary between normal and pronated feet.
Lectin Histochemistry of Peyer's Patches in the Porcine Ileum. (2002)

Lectin staining pattern in Peyer's patches of porcine ileum was studied using twenty one biotinylated-labeled lectins as cell markers which were visualized with avidin-biotin-peroxidase complex method (ABC). WGA appears to be a selective marker for tingible body macrophages in the porcine germinal centers. ConA may be a positive marker for the lymphoid tissues, whereas 9 lectins (DBA, SBA, SJA, s-WGA, PNA, ECL, UEA-I, PHA-E, and PHA-L) may be negative markers for the lymphoid tissues in all areas.
OPTIMIZATION OF GROWTH AND BIOACTIVE METABOLITE PRODUCTION: FUSARIUM SOLANI. (2013)

The present study aimed to evaluate optimize the growth and antibacterial activity of endophytic fungi isolated from Tylophora indica. Based on the morphological and molecular characteristic, the isolate was identified as Fusarium solani. Modified liquid medium (M2D) was used as a basal medium for growth and antibacterial activity. The growth and metabolite production were optimized with 4% dextrose, 0.05% yeast extract and aspartic acid (0.01%) as carbon, nitrogen and amino acid respectively. The optimum pH and temperature of the strain were 6.0, 25Â±2 Â°C observed for growth and secondary metabolite production. The 9th day was found to be optimum incubation period of growth and secondary metabolite production. The metabolite showed maximum inhibition against Enterococcus faecalis, lowest inhibition zone was against Yersinia enterocolitica. The ESI-MS analysis of bio active compound shows the peak at 301m/z. Key words: Endophytic fungus, Tylophora indica, antibacterial activity, Medium Optimization, ESI -MS
Increased understanding of platinum anticancer chemistry (2011)

The development of a few worldwide routinely used Pt(II) coordination compounds is described from a mechanistic point of view and related to the molecular aspects of Pt-DNA binding. Mechanistic knowledge developed from these studies is applied nowadays for the design and synthesis of new bifunctional and trifunctional compounds, aimed for use as improved anticancer drugs.
S-band maser phase delay stability tests (1978)

The results of the S-band traveling wave maser phase delay stability measurements performed at DSS 62 are presented. These tests were required for the Pioneer-Venus wind experiment.
Phenotypic Characterization of Neisseria gonorrhoeae Isolated from Three Cases of Meningitis (1986)

Journal Article Phenotypic Characterization of Neisseria gonorrhoeae Isolated from Three Cases of Meningitis Get access Roselyn J. Rice, Roselyn J. Rice Search for other works by this author on: Oxford Academic PubMed Google Scholar William O. Schalla, William O. Schalla Search for other works by this author on: Oxford Academic PubMed Google Scholar W. L. Whittington, W. L. Whittington Search for other works by this author on: Oxford Academic PubMed Google Scholar Yucynthia JeanLouis, Yucynthia JeanLouis Search for other works by this author on: Oxford Academic PubMed Google Scholar James W. Biddle, James W. Biddle Search for other works by this author on: Oxford Academic PubMed Google Scholar Martin Goldberg, Martin Goldberg Search for other works by this author on: Oxford Academic PubMed Google Scholar Wallis DeWitt, Wallis DeWitt Search for other works by this author on: Oxford Academic PubMed Google Scholar Carol A. Pasquariello, Carol A. Pasquariello Search for other works by this author on: Oxford Academic PubMed Google Scholar Elias Abrutyn, Elias Abrutyn Search for other works by this author on: Oxford Academic PubMed Google Scholar Robert Swenson Robert Swenson Search for other works by this author on: Oxford Academic PubMed Google Scholar The Journal of Infectious Diseases, Volume 153, Issue 2, February 1986, Pages 362–365, https://doi.org/10.1093/infdis/153.2.362 Published: 01 February 1986 Article history Received: 14 February 1985 Revision received: 10 September 1985 Published: 01 February 1986
Recent advances in SAW packaging (2002)

Continuous size reduction of today's mobile telephones in parallel with enhanced functionality demands for higher integration of components as well as for significantly reduced device and component size. Since modern surface acoustic wave (SAW) components combine superior filter functionality with small size, they play an important role in mobile phone evolution. Increasing the levels of functional integration and permanent miniaturization are therefore the major driving forces in current SAW filter development. Conventional wire-bonded ceramic, metal or plastic packages are to an increasing degree being replaced by space efficient flip-chip or chip-scale packages. EPCOS' proprietary packaging technology chip sized SAW package (CSSP) combines consequent package size reduction, filter application-specific technological features and outstanding internal electromagnetic performance made possible by the flip-chip technology. Specific CSSP technologies - each offering an optimum ratio between active chip space and package size - were developed for lower frequency (e.g. CDMA-IF) filters as well as for extremely frequency-precise IF-filters (e.g. GSM-IF), 1 GHz and 2 GHz RF filters, respectively. As functional integration like balun functionality or impedance transformation becomes more and more important for RF SAW filters, an integral design approach including acoustical and 3-D electromagnetic effects has to be used. The influence of sophisticated electromagnetic package design will be illustrated by examples resulting e.g. in superior amplitude and phase symmetry of balanced RF filters. Further size reduction will be obtained by integrating SAW filters with active as well as passive components in the frontend of cellular terminals.
Effects of Eplerenone, a Selective Aldosterone Blocker, on the Progression of Left Ventricular Dysfunction and Remodeling in Rats with Dilated Cardiomyopathy (2004)

Aldosterone blockade reduces morbidity and mortality in patients with heart failure. We studied the effects of eplerenone, a novel aldosterone blocker, on the progression of left ventricular dysfunction and remodeling in rats with dilated cardiomyopathy after autoimmune myocarditis. Twenty-eight days after immunization, the surviving Lewis rats were randomized to 1 month's oral treatment with low-dose eplerenone (group L), high-dose eplerenone (group H) or vehicle (group V). Five of 15 (33%) rats in group V and 3 of 15 (20%) rats in group L died during the course of treatment. High-dose eplerenone significantly reduced cardiomyocyte hypertrophy, heart weight and heart weight to body weight ratio. Eplerenone improved left ventricular function in a dose-dependent manner. Central venous pressure and left ventricular end-diastolic pressure were lower, and +/-dP/dt and fractional shortening were higher in group H than group V. Eplerenone also attenuated myocardial fibrosis and reduced left ventricular mRNA expressions of TGF-beta(1) and collagen-III. Our results indicate that treatment with eplerenone improved left ventricular dysfunction and attenuated left ventricular remodeling in rats with heart failure.
Recurrent circuits within medial entorhinal cortex superficial layers support grid cell firing (2018)

Specialized cells in the medial entorhinal cortex (mEC), such as speed cells, head direction (HD) cells, and grid cells, are thought to support spatial navigation. To determine whether these computations are dependent on local circuits, we record neuronal activity in mEC layers II and III and optogenetically perturb locally projecting layer II pyramidal cells. We find that sharply tuned HD cells are only weakly responsive while speed, broadly tuned HD cells, and grid cells show pronounced transient excitatory and inhibitory responses. During the brief period of feedback inhibition, there is a reduction in specifically grid accuracy, which is corrected as firing rates return to baseline. These results suggest that sharp HD cells are embedded in a separate mEC sub-network from broad HD cells, speed cells, and grid cells. Furthermore, grid tuning is not only dependent on local processing but also rapidly updated by HD, speed, or other afferent inputs to mEC.
Bimetallic iron–rhodium anionic carbonyl clusters: [Fe2Rh(CO)x]–(x= 10 or 11), [FeRh4(CO)15]2–, [Fe2Rh4(CO)16]2–, and [FeRh5(CO)16]– (1983)

The synthesis and chemical behaviour of the new iron-rhodium anionic carbonyl clusters [Fe2Rh(CO)x]–(x= 10 or 11), [FeRh4(CO)15]2–, [Fe2Rh4(CO)16]2–, and [FeRh5(CO)16]– are reported. Low-temperature multinuclear n.m.r. studies (13C,13C-{103Rh}, and 103Rh) on the penta- and hexa-nuclear clusters allow their structures in solution to be unambiguously established and their fluxional behaviour has been investigated through variable-temperature measurements. None shows rearrangement of the metal polyhedron.
Auto-tuning TensorFlow Threading Model for CPU Backend (2018)

TensorFlow is a popular deep learning framework used by data scientists to solve a wide-range of machine learning and deep learning problems such as image classification and speech recognition. It also operates at a large scale and in heterogeneous environments --- it allows users to train neural network models or deploy them for inference using GPUs, CPUs and deep learning specific custom-designed hardware such as TPUs. Even though TensorFlow supports a variety of optimized backends, realizing the best performance using a backend may require additional efforts. For instance, getting the best performance from a CPU backend requires careful tuning of its threading model. Unfortunately, the best tuning approach used today is manual, tedious, time-consuming, and, more importantly, may not guarantee the best performance. In this paper, we develop an automatic approach, called TensorTuner, to search for optimal parameter settings of TensorFlow's threading model for CPU backends. We evaluate TensorTuner on both Eigen and Intel's MKL CPU backends using a set of neural networks from TensorFlow's benchmarking suite. Our evaluation results demonstrate that the parameter settings found by TensorTuner produce 2% to 123% performance improvement for the Eigen CPU backend and 1.5% to 28% performance improvement for the MKL CPU backend over the performance obtained using their best-known parameter settings. This highlights the fact that the default parameter settings in Eigen CPU backend are not the ideal settings; and even for a carefully hand-tuned MKL backend, the settings may be sub-optimal. Our evaluations also revealed that TensorTuner is efficient at finding the optimal settings --- it is able to converge to the optimal settings quickly by pruning more than 90% of the parameter search space.
Sicherheit und Wirksamkeit interferonfreier antiviraler Therapien in der Behandlung fortgeschrittener HCV-assoziierter Leberzirrhose: Ergebnisse aus dem Deutschen Hepatitis C-Register (DHC-R) (2016)

Einleitung/Ziele: Direkt antivirale Substanzen (DAA) verbessern die Wirksamkeit der Behandlung einer chron. Hepatitis C-Virusinfektion (HCV). Phase 3-Studien deuteten auf geringere Ansprechraten bei Patienten mit Leberzirrhose hin. Informationen zur Wirksamkeit von DAA-Therapien bei Patienten mit fortgeschrittener Leberzirrhose sind nur begrenzt verfügbar. Nicht bekannt ist, in welchem Ausmaß interferonfreie Therapien die Leberfunktion dieser Patienten verbessern.