gebhart/patrepeval huggingface dataset:
Advanced Module Concepts (2016)

It is very hard to produce the most reliable photovoltaic (PV) module at the lowest cost. Current PV modules are designed to operate in any location, under any climatic conditions. Anti-reflection coating (ARC) on the front surface of the glass of PV modules has been widely used in production since about 2010. Two main methods are uses to form an ARC on glass for PV applications: etching the surface of the glass or depositing a film of porous glass. The light reflective film (LRF) structure is composed of grooves with a good specular reflection and a facet angle greater than 22 degree to force the reflected light to be totally internally reflected inside the module. Light capturing ribbons (LCR) and LRF are technologies that allow light rays that are reflected by the ribbons or that fall between cells to be totally internally reflected within the module and captured by the solar cells.
Proteomics approach to identify serum biomarkers associated with the progression of diabetes in Korean patients with abdominal obesity (2019)

Type 2 diabetes is a metabolic disease with a group of metabolic derangements and inflammatory reactants in the serum. Despite the substantial public health implications, markers of diabetes progression with abdominal obesity are still needed to facilitate early detection and treatment. In this study, we performed a proteomic approach to identify differential target proteins underlying diabetes progression in patients with abdominal obesity. Proteomic differences were investigated in the serum of controls and patients with prediabetes or diabetes with or without abdominal obesity by 2-DE combined with MALDI-TOF-MS. Proteomics data were validated by western blot analyses and major protein-protein interactions were assessed using a network analysis with String database. Among 245 matched protein spots, 36 exhibited marked differences in normal patients with abdominal obesity, prediabetes, and diabetes compared to levels in normal patients without abdominal obesity. Seven (Alpha-1-antichymotrypsin, Alpha-1-antitrypsin, Apolipoprotein A-I, haptoglobin, retinol-binding protein 4, transthyretin, and zinc-alpha2-glycoprotein) of these spots exhibited significant differences between normal and prediabetes/diabetes patients. After a network analysis, functional annotation using Gene Ontology indicated that most of the identified proteins were involved in lipid transport, lipid localization, and the regulation of serum lipoprotein particle levels. Our results indicated that variation in the levels of these identified protein biomarkers has been reported in normal, prediabetes and diabetic Assessment of the levels of these biomarkers may contribute to the development of biomarkers for not only early diagnosis but also in prognosis of diabetes mellitus type 2.
Preparation and Application of Triple Helix Forming Oligonucleotides and Single Strand Oligonucleotide Donors for Gene Correction (2014)

Strategies for site-specific modulation of genomic sequences in mammalian cells require two components. One must be capable of recognizing and activating a specific target sequence in vivo, driving that site into an exploitable repair pathway. Information is transferred to the site via participation in the pathway by the second component, a donor nucleic acid, resulting in a permanent change in the target sequence. We have developed biologically active triple helix forming oligonucleotides (TFOs) as site-specific gene targeting reagents. These TFOs, linked to DNA reactive compounds (such as a cross-linking agent), activate pathways that can engage informational donors. We have used the combination of a psoralen-TFO and single strand oligonucleotide donors to generate novel cell lines with directed sequence changes at the target site. Here we describe the synthesis and purification of bioactive psoralen-linked TFOs, their co-introduction into mammalian cells with donor nucleic acids, and the identification of cells with sequence conversion of the target site. We have emphasized details in the synthesis and purification of the oligonucleotides that are essential for preparation of reagents with optimal activity.
Quantification of Coarse Aggregate Surface Texture Using Image Analysis (2006)

Abstract Aggregate surface texture affects the performance of pavement and railroad track structural layers, such as the unbound aggregate base/ballast, asphalt concrete, and Portland cement concrete. A quantitative surface texture (ST) index is defined in this paper based on image analysis to measure the irregularities on the surface of coarse aggregate particles in the extent that is not characterized by the commonly used large-scale morphological descriptors, such as flatness, elongation, and angularity. Using an image analysis approach referred to as erosion and dilation, the new ST index quantifies the coarse aggregate surface irregularities at the pixel level. Samples of natural gravel and crushed aggregate were used in establishing a realistic range for the ST index independent of particle size. The effectiveness and practical applicability of the defined ST index in characterizing aggregate surface texture were evaluated by measuring surface irregularities or texture of commonly used coarse aggregate materials.
Click Chemistry Grafting of Poly(ethylene glycol) Brushes to Alkyne-Functionalized Pseudobrushes (2009)

A versatile method for the grafting of azide-terminated polymer chains to alkyne-functionalized pseudobrushes by the Cu(I)-catalyzed Huisgen 1,3-dipolar cycloaddition has been developed. First, poly[(propargyl methacrylate)-r-(glycidyl methacrylate)-r-(methyl methacrylate)] random copolymers with monomer ratios of respectively 27/27/46, 41/31/28, and 45/55/0 were synthesized by RAFT polymerization. Then, dense alkyne-functionalized pseudobrushes were grafted in melt by thermal ring-opening of the glycidyl groups by the silanols from the silicon substrate. Finally, the grafting of tailor-made alpha-methoxy-omega-azido-poly(ethylene glycol)s (M(w) approximately 5000, 20,000, and 50,000 g/mol) by Cu(I)-catalyzed Huisgen 1,3-dipolar cycloaddition was performed in sealed reactors at 60 degrees C for 72 h using a polymer weight fraction of 10% in tetrahydrofuran and Cu(PPh(3))(3)Br/DIPEA as the catalytic system. Alkyne-functionalized pseudobrushes and poly(ethylene glycol) brushes were characterized by ellipsometry, scanning probe microscopy, and water contact angle measurements. This "grafting-to" approach represents a fast and versatile method to provide thick and homogeneous polymer brushes with a high surface coverage. A major benefit of this strategy is the tunable and versatile tethering of alkyne functionalities to silicon substrates using a straightforward spin-coating procedure.
Can microfluidics address biomanufacturing challenges in drug/gene/cell therapies? (2016)

Translation of any inventions into products requires manufacturing. Development of drug/gene/cell delivery systems will eventually face manufacturing challenges, which require the establishment of standardized processes to produce biologically-relevant products of high quality without incurring prohibitive cost. Microfluidicu technologies present many advantages to improve the quality of drug/gene/cell delivery systems. They also offer the benefits of automation. What remains unclear is whether they can meet the scale-up requirement. In this perspective, we discuss the advantages of microfluidic-assisted synthesis of nanoscale drug/gene delivery systems, formation of microscale drug/cell-encapsulated particles, generation of genetically engineered cells and fabrication of macroscale drug/cell-loaded micro-/nano-fibers. We also highlight the scale-up challenges one would face in adopting microfluidic technologies for the manufacturing of these therapeutic delivery systems.
Raman suppression in kW-level narrow-linewidth one-stage MOPA fiber laser by CTFBG (2021)

The one-stage master oscillator power amplifier (MOPA) is an efficient way to acquire high-power narrow-linewidth fiber lasers (NLFLs), which have wide usage in beam combination and detection. However, stimulated Raman scattering (SRS) is still one of the main obstacles for further power scaling. In this paper, we set up a counter-pumping kW-level narrowlinewidth one-stage MOPA fiber laser system and tried to use a chirped and tilted fiber Bragg grating (CTFBG) as a broadband rejection filter to suppress the Raman stokes light in the output laser. We finally acquired a 2.5 kW output with 3 dB linewidth of about 0.87 nm, and the SRS isolation ratio is ~42 dB on the spectrum, which is 12.7 dB higher compared with the situation without CTFBG.
Optical and In-Depth RBS Characterization of Porous Silicon Interference Filters (2005)

In the present work, Rutherford backscattering spectroscopy (RBS) measurements, scanning electron microscopy, and optical characterization are carried out on porous silicon (PS) multilayer interference filters in order to determine their compositional profile, homogeneity, and overall optical behavior. In addition, RBS measurements allow determination of the porosity profile of multilayer structures. Thus, both porosity and oxidation degree are determined for each individual layer forming the stack, giving a straightforward measure of the in-depth homogeneity of these structures. Finally, the aging effects on the optical behavior and compositional profile of the PS stacks are studied by comparing as-prepared and aged multilayers. The results reveal good in-depth homogeneity of the PS multilayers and an oxygen enrichment with ambient air exposure, which results in a lowering of the effective refractive index and a blueshift of the reflectance spectra of the filters.
Characteristics of circulating KSHV-infected viroblasts during active KSHV+ multicentric Castleman disease (2022)

Kaposi sarcoma-associated herpesvirus (KSHV)/human herpesvirus 8-associated multicentric Castleman disease (MCD) is a polyclonal B-cell lymphoproliferative disorder that mainly occurs in immunocompromised hosts. The diagnosis relies on lymph node biopsy demonstrating KSHV-infected cells located in the mantle zone with a marked interfollicular plasma cell infiltration. Infected cells are large cells positive for immunoglobulin M (IgM), λ light chain, and CD38, described initially as infected plasmablasts. We show that IgM+λ+CD38high cells were also detectable in the peripheral blood of 14 out of 18 (78%) patients with active KSHV-MCD and absent in 40 controls. Using immunofluorescence and flow-fluorescence in situ hybridization, we demonstrate that these cells are KSHV infected and express both latent and lytic KSHV transcripts. These KSHV-infected viroblasts (KIVs) harbor a distinct phenotype compared with conventional plasmablasts. We also identified several putative mechanisms of immune escape used by KSHV, because KIVs displayed an overall decrease of costimulatory molecules, with a remarkable lack of CD40 expression and are interleukin-10-producing cells. The identification of this specific and easily accessible KSHV+ circulating population brings new elements to the understanding of KSHV-MCD but also raises new questions that need to be clarified.
A Methylviologen Lead(II) Iodide:  Novel [PbI3-]∞ Chains with Mixed Octahedral and Trigonal Prismatic Coordination (1998)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTA Methylviologen Lead(II) Iodide: Novel [PbI3-]∞ Chains with Mixed Octahedral and Trigonal Prismatic CoordinationZhongjia Tang and Arnold M. GuloyView Author Information Department of Chemistry and Texas Center for Superconductivity University of Houston, Houston, Texas 77204-5641 Cite this: J. Am. Chem. Soc. 1999, 121, 2, 452–453Publication Date (Web):December 29, 1998Publication History Received30 July 1998Published online29 December 1998Published inissue 1 January 1999https://pubs.acs.org/doi/10.1021/ja982702ihttps://doi.org/10.1021/ja982702irapid-communicationACS PublicationsCopyright © 1999 American Chemical SocietyRequest reuse permissionsArticle Views1508Altmetric-Citations124LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information SUBJECTS:Anions,Cations,Crystal structure,Group theory,Mathematical methods Get e-Alerts
HPV Vaccine Protein L1 Predicts Disease Outcome of High-Risk HPV+ Early Squamous Dysplastic Lesions (2009)

Prediction of the clinical outcome of nonadvanced, early dysplastic lesions is one of the unresolved problems of cervical cancer screening programs. We examined the influence of human papillomavirus (HPV) L1 capsid protein detection in a randomized, prospective study of 187 high-risk HPV+ early dysplastic lesions during 36 to 46 months. The difference in the clinical outcome of the HPV L1- cases and the HPV L1+ cases was highly statistically significant (P < .0001) and independent of the classification of low-grade squamous intraepithelial lesion (mild dysplasia) and high-grade squamous intraepithelial lesion of the moderate dysplastic type. L1+ mild and moderate dysplasias, reflecting productive HPV infection, showed low malignant potential, justifying a wait-and-watch strategy to prevent overtreatment, especially in young women. L1- early dysplastic lesions, as nonproductive infections or precancerous lesions, have a high malignancy potential and close follow-up with colposcopy and histologic evaluation should be advised.
Dielectric spectroscopy as a tool for the measurement of the formation of biofilms and of their removal by electrolytic cleaning pulses and biocides (1990)

Dielectric spectroscopy can be used as an on‐line method for the measurement of the formation of biofilms. The formation of a biofilm by the organism Klebsiella rubiacearum was measured by registering changes in the capacitance in the frequency range 0–1–10 MHz using a 4‐terminal gold pin dielectric spectrometer. Removal and prevention of biofilms by electrolytic cleaning pulses was investigated. The effect of the addition of the biocides cetrimide, chlorine and glutaraldehyde was studied. The usefulness of the method in the on‐line control of biofilms was demonstrated in an experiment in which the biofilm level was controlled by the automated addition of chlorine in response to appropriate changes in the electrical capacitance.
Handbook of Clinical Anesthesia (1991)

Handbook of Clinical Anesthesia 6/e - Libros de Medicina - Anestesiologia y Reanimacion - 40,85
Influence of image sequence distortion on infrared target detection (2017)

Because of the platform motion and system internal asymmetric structure, Satellite-borne infrared imaging system will generate image geometric distortions such as translation, rotation, distortion and scaling, which make the subsequent target detection result not accurate. Therefore, we propose an image distortion method and deeply analyze the influence of infrared image distortion on the SNR of infrared weak small targets, detection probability and false alarm probability. The simulation results show that the image distortion directly affects the subsequent performance of the infrared target detection and tracking algorithm by changing target geometric imaging and signal to noise ratio. The research result in this paper would have great application value in the satellite-borne infrared alarm/warning system.
Coronary artery stents microfabricated from planar metal foil: design, fabrication, and mechanical testing (2003)

This paper presents a new approach to the design and manufacture of coronary artery stents, which permits the use of planar batch fabrication technologies. Stent samples with different wall patterns have been fabricated from 50-/spl mu/m thick stainless steel foil using micro-electro-discharge machining, and expanded to tubular shapes by using angioplasty balloons. The stents exhibit diameter variations of 10/spl times/ higher.
Latest Gear Cutting Technology that Improves Customer Productivity (Increase in Speed of ST Series NC Guide Gear Shaping Machine) (2012)

Mitsubishi Heavy Industries, Ltd. (MHI) was the first company in the world to establish the dry cut system, which contributes to a clean work environment and high productivity by eliminating the use of cutting oil for the processing of gears. We have been actively offering new technologies, including the one mentioned above, that satisfy the needs of customers. There is a growing need for further improvement of productivity, including the reduction of processing time, from mass production lines of automobiles and other products, as well as from job shops that manufacture multiple types of gears in small quantity. In this paper, we will introduce the latest technologies for productivity improvement of gear cutting machines, taking the ST series NC guide gear shaping machine, one of the gear cutting machines developed by MHI, as an example. |1. Introduction A gear shaper is a gear cutting machine that is generally used to process internal gears and stepped gears. As shown in Figure 1, the cutter and the workpiece are rotated synchronously while the cutter is moved back and forth for processing gears. The gear shaper features a unique function, where a helical guide is used to move gears helically along the cutter lead for the processing of helical gears that are twisted along the helical path. The helical guide needs to be replaced responding to the change of the cutter lead, but helical guides are expensive and replacement requires a fair amount of time and a lot of skill. MHI’s ST series NC guide gear shaping machine eliminated the need for the replacement of the guide by numerically controlling the helical movement at high speed and high precision. Utilizing this technology, the functions of the ST40CNC model, for which the need for productivity improvement is especially high, were improved.
A Theoretical Model of Industrial Economy Inflationary Dynamics (2004)

A standard monetary model of inflation is augmented to include import, labor, energy, and intermediate good cost pressures. Expansion of the original monetary framework is achieved using a cost function dual of the production function. Implications for parameter magnitudes and other empirical issues are discussed with respect to potential estimation procedures.
Effect of Bronchoscopic Lung Volume Reduction on Dynamic Hyperinflation and Exercise in Emphysema (2004)

Endobronchial valve placement improves pulmonary function in some patients with chronic obstructive pulmonary disease, but its effects on exercise physiology have not been investigated. In 19 patients with a mean (SD) FEV(1) of 28.4 (11.9)% predicted, studied before and 4 weeks after unilateral valve insertion, functional residual capacity decreased from 7.1 (1.5) to 6.6 (1.7) L (p = 0.03) and diffusing capacity rose from 3.3 (1.1) to 3.7 (1.2) mmol . minute(-1) . kPa(-1) (p = 0.03). Cycle endurance time at 80% of peak workload increased from 227 (129) to 315 (195) seconds (p = 0.03). This was associated with a reduction in end-expiratory lung volume at peak exercise from 7.6 (1.6) to 7.2 (1.7) L (p = 0.03). Using stepwise logistic regression analysis, a model containing changes in transfer factor and resting inspiratory capacity explained 81% of the variation in change in exercise time (p < 0.0001). The same variables were retained if the five patients with radiologic atelectasis were excluded from analysis. In a subgroup of patients in whom invasive measurements were performed, improvement in exercise capacity was associated with a reduction in lung compliance (r(2) = 0.43; p = 0.03) and isotime esophageal pressure-time product (r(2) = 0.47; p = 0.03). Endobronchial valve placement can improve lung volumes and gas transfer in patients with chronic obstructive pulmonary disease and prolong exercise time by reducing dynamic hyperinflation.
Structural and biochemical characterization of engineered tissue using FTIR spectroscopic imaging: melanoma progression as an example (2008)

Engineered tissue represents a convenient path to providing models for imaging and disease progression. The use of these models or phantoms is becoming increasingly prevalent. While structural characterization of these systems is well-documented, a combination of biochemical and structural knowledge is often helpful. Fourier transform infrared (FTIR) spectroscopic imaging is a rapidly emerging technique that combines the molecular selectivity of spectroscopy with the spatial specificity of optical microscopy. Here, we report on the application of FTIR spectroscopic for analysis of a melanoma model in engineered skin. We first characterize the biochemical properties, consistency and spectral changes in different layers of growing skin. Results provide simple indices for monitoring tissue consistency and reproducibility as a function of time. Second, we introduce malignant melanocytes to simulate tumor formation and growth. Both cellular changes associated with tumor formation and growth can be observed. FTIR images indicate holistic chemical changes during the tumor growth, allowing for the development of automated pathology protocols. FTIR imaging being non-destructive, further, samples remain entirely compatible with downstream tissue processing or staining. We specifically examined the correlation of structural changes, molecular content and reproducibility of the model systems. The development of analysis, integrating spectroscopy, imaging and computation will allow for quality control and standardization of both the structural and biochemical properties of tissue phantoms.
Einige Probleme der Qualitätskontrolle von tiefgefrorenen Fischerzeugnissen (1969)

Abstract Für die Qualitätskontrolle in der modernen Fischwirtschaft gelten die gleichen Prinzipien wie in der übrigen Lebensmittelwirtschaft. Am Beispiel der tiefgefrorenen Fischprodukte wird der gegenwärtige Mangel an schnellen, zuverlässigen und allgemein anerkannten Qualitätskontrollmethoden dargestellt. Insbesondere auf dem Gebiet der Gütekontrolle ist eine Entwicklung solcher Prüfungsanleitungen dringend notwendig. Für Frischegrad, Ranziditätsgrad und Konsistenz müssen geeignete Schnellmethoden entwickelt werden. Die sensorischen Prüfverfahren müssen vereinheitlicht werden. Eine Prüfung all dieser Methoden durch mehrere Fachleute wäre anzustreben. Die Arbeiten müßten auf Fische ausgedehnt werden, die verschiedenen Arten angehören, von verschiedenen Fanggründen stammen und zu verschiedenen Jahreszeiten gefangen werden. Erst, wenn statistisch gesicherte Ergebnisse vorliegen, können Qualitätsstandards aufgestellt werden.