gebhart/patrepeval huggingface dataset:
IDDF2019-ABS-0118 Electroacupuncture plus on-demand gastrocaine for refractory functional dyspepsia: pragmatic randomized trial (2019)

<h3>Background</h3> Treatment options for functional dyspepsia (FD) refractory to pharmacological treatments are limited, but the effectiveness of electroacupuncture (EA) is uncertain. Our aim was to assess the effectiveness of EA combined with on-demand gastrocaine. <h3>Methods</h3> We conducted a single-centre, assessor-blind, randomized parallel-group 2-arm trial on <i>H. pylori</i> negative FD patients of the postprandial distress syndrome (PDS) subtype refractory to proton pump inhibitor, prokinetics or H<sub>2</sub> antagonists. Enrolled participants were block randomized in a 1:1 ratio, with concealed random sequence. The treatment and control groups both received on-demand gastrocaine for 12 weeks, but only those in treatment group were offered 20 sessions of EA over 10 weeks. The primary endpoint was the between-group difference in the proportion of patients achieving adequate relief of symptoms at week 12. <h3>Results</h3> Of 132 participants randomly assigned to EA plus on-demand gastrocaine (<i>n</i> = 66) or on-demand gastrocaine alone (<i>n</i> = 66), 125 (94.7%) completed all follow-up at 12 weeks. The EA group had a compliance rate 97.7%. They had a significantly higher likelihood in achieving adequate symptom relief at 12 weeks, with a clinically relevant number needed to treat (NNT) value of 2.36 (95%CI: 1.74–3.64). Among secondary outcomes, statistically and clinically significant improvements were observed among global symptom (NNT=3.85 (95%CI: 2.63, 7.69)); postprandial fullness and early satiation (NNT=5.00 (95%CI:2.86, 25.00)); as well as epigastric pain, epigastric burning and postprandial nausea (NNT=4.17 (95%CI: 2.56, 11.11)). Adverse events were minimal and non-significant. <h3>Conclusions</h3> For refractory FD, EA provides significant, clinically relevant symptom relief when added to on-demand gastrocaine. (ChiCTR-IPC-15007109)
A Conformable Force/Tactile Skin for Physical Human–Robot Interaction (2015)

In this letter, a new sensorized flexible skin has been used to enhance safety and intuitiveness of physical human-robot interaction (HRI) in applications where both intentional and unintentional contacts may occur. The new technological contribution with respect to other skin sensors consists of the capability of measuring both the position of the contact point and the three components of the applied force with high repeatability and accuracy. To show how this innovative technology enables the exploitation of control laws for intuitive HRI, two standard control strategies have been implemented to perform both manual guidance with multiple contact points and safe reaction in case of unintentional collision detection, at the same time. In both cases, an admittance control scheme with a second order kinematic control is adopted. A multipriority redundancy resolution strategy is implemented in the case of manual guidance. The experimental verification of the sensor capabilities is made using a patch of the skin installed on a link of a KUKA LWR4 robot.
ATS-6 Spacecraft Attitude Precision Pointing&Slewing Adaptive Control Experiment (1975)

The primary objective of the Spacecraft Attitude Precision Pointing and Slewing Adaptive Control (SAPPSAC) Experiment is to establish feasibility and evaluate capabilities of a ground-based spacecraft attitude control system, wherein RF command and telemetry links, together with a ground station on-line minicomputer, perform closed loop attitude control of the Applications Technology Satellite -6 (ATS-6). The ground processor is described, including operational characteristics and the controller software. Attitude maneuvers include precision pointing to fixed targets, slewing between targets, and generation of prescribed ground tracks. Test results show high performance and reliability for over 30 h of on-line control with no serious anomalies. Attitude stabilization relative to a prescribed target has been achieved to better than 0.007° in pitch and roll and 0.020° in yaw for a period of 43 min. Ground tracks were generated which had maximum latitude/longitude deviations less than 0.150 from reference.
Asymptotic boundary conditions for strip-loaded and corrugated surfaces (1997)

We discuss the unidirectional current screen as an asymptotic strip boundary condition (ASBC) for analysis of field problems containing metal strip grids, and we introduce a related asymptotic corrugation boundary condition (ACBC) for analysis of corrugated surfaces. The boundary conditions are asymptotic in the sense that the exact boundary conditions approach the asymptotic ones when the strip and corrugation periods approach zero. © 1997 John Wiley & Sons, Inc. Microwave Opt Technol Lett 14: 99–101, 1997.
Asthma, Rhinitis, and Skin Test Reactivity to Aeroallergens in Families of Asthmatic Subjects in Anqing, China (2001)

In industrialized countries with a Western lifestyle, sensitization to perennial aeroallergens is strongly associated with asthma, whereas sensitization to seasonal aeroallergens is closely related to allergic rhinitis. Little is known, however, about the relation between skin test reactivity to aeroallergens and either asthma or rhinitis in mainland China. We studied 10,009 members of 2,544 families in Anqing (China) that were selected on the basis of physician-diagnosed asthma in at least two siblings. Generalized estimating equations were employed to study the association between skin test reactivity to aeroallergens and either asthma or rhinitis. After adjustment for age, sex, intensity of smoking, skin test reactivity to other aeroallergens, and household correlations, sensitization to dust mite was an independent predictor of both asthma (OR = 1.3, 95% CI = 1.1 to 1.5, p = 0.008) and rhinitis (OR = 1.3, 95% CI = 1.0 to 1.8, p = 0.04). Sensitization to mold was significantly associated with asthma (OR = 1.6, 95% CI = 1.1 to 2.3, p = 0.008), and sensitization to silk was an independent predictor of rhinitis (OR = 1.5, 95% CI = 1.1 to 2.2, p = 0.02). Although 46.9% of the study participants were sensitized to at least one allergen, only 3.5% of study subjects reported nasal symptoms consistent with rhinitis. Among asthmatic subjects, 6.2% reported nasal symptoms. Whereas sensitization to perennial aeroallergens was associated with asthma among families of asthmatic subjects in rural China, sensitization to silk was the strongest predictor of rhinitis in this population. Our findings also suggest that allergic rhinitis is far less common among asthmatic subjects in rural China than in asthmatic subjects in industrialized countries with a Western lifestyle.
Therapeutic potential of irreversible electroporation in sarcoma (2012)

Irreversible electroporation is a newly developed nonthermal tissue ablation technique in which certain short-duration electrical fields are used to permanently permeabilize the cell membrane to disrupt cellular homeostasis. This disruption of cellular homeostasis initiates apoptosis, which leads to permanent cell death. Sarcomas are generally divided into soft-tissue and bone sarcomas based on their different mesenchymal origins and anatomical locations. Each of these sarcomas present in different ways, exhibit different behaviors and prognoses, and present unique therapeutic challenges. In this article, a series of recently conducted irreversible electroporation treatment for sarcomas based on local nonthermal ablation are summarized, and the therapeutic potential of this newly developed technique is assessed.
Extending the Battery Life of Smartphones and Tablets: A Practical Approach to Optimizing the LTE Network (2014)

This article provides a practical approach to optimize the long-term evolution (LTE) network to extend the battery life of LTE devices such as smartphones and tablets. The majority of the commercially deployed LTE networks are optimized for data dongles where the battery consumption is not a major concern. With the introduction of LTE smartphones and tablets and other handheld LTE devices, battery consumption has become a major bottleneck to the end user. In this article, we analyze, evaluate, and validate the key relevant features and parameters that can potentially reduce the battery consumption and, hence, extend the device usage time. The objective of this article is to obtain the optimum parameters setting for relevant LTE features to efficiently deliver non-real-time applications with bursty traffic over the LTE network by providing power savings without perceptibly degrading the user experience. The connected and idle-mode discontinuous reception (DRX) mechanism along with the user inactivity timer (UIT) are assessed and evaluated by means of field testing in a live LTE network to identify the optimal deployment scenario for the most common data applications in a commercially deployed LTE network.
Osteoporosis, fractures, and risk of falls. (2010)

Osteoporosis in elderly cancer patients is an increasing problem, yet it remains under-recognized and under-managed. We commend Dr. Balducci for writing a comprehensive review of the bone complications associated with cancer and its treatment in the elderly.
Does Long-Term Elevation of CO2 Concentration Increase Photosynthesis in Forest Floor Vegetation? (Indiana Strawberry in a Maryland Forest) (1997)

As the partial pressure of CO2 (pCO2) in the atmosphere rises, photorespiratory loss of carbon in C3 photosynthesis will diminish and the net efficiency of light-limited photosynthetic carbon uptake should rise. We tested this expectation for Indiana strawberry (Duchesnea indica) growing on a Maryland forest floor. Open-top chambers were used to elevate the pCO2 of a forest floor habitat to 67 Pa and were paired with control chambers providing an ambient pCO2 of 38 Pa. After 3.5 years, D. indica leaves grown and measured in the elevated pCO2 showed a significantly greater maximum quantum efficiency of net photosynthesis (by 22%) and a lower light compensation point (by 42%) than leaves grown and measured in the control chambers. The quantum efficiency to minimize photorespiration, measured in 1% O2, was the same for controls and plants grown at elevated pCO2. This showed that the maximum efficiency of light-energy transduction into assimilated carbon was not altered by acclimation and that the increase in light-limited photosynthesis at elevated pCO2 was simply a function of the decrease in photorespiration. Acclimation did decrease the ribulose-1,5-bisphosphate carboxylase/oxygenase and light-harvesting chlorophyll protein content of the leaf by more than 30%. These changes were associated with a decreased capacity for light-saturated, but not light-limited, photosynthesis. Even so, leaves of D. indica grown and measured at elevated pCO2 showed greater light-saturated photosynthetic rates than leaves grown and measured at the current atmospheric pCO2. In situ measurements under natural forest floor lighting showed large increases in leaf photosynthesis at elevated pCO2, relative to controls, in both summer and fall. The increase in efficiency of light-limited photosynthesis with elevated pCO2 allowed positive net photosynthetic carbon uptake on days and at locations on the forest floor that light fluxes were insufficient for positive net photosynthesis in the current atmospheric pCO2.
Evaluation of a surgical simulator for learning clinical anatomy (2004)

Our results show that this surgical simulator is at least as effective as textbook images for learning anatomy and could enhance student learning through increased motivation. These findings provide insight into simulator development and strategies for learning anatomy. Possible explanations and future research directions are discussed.
Solid-State Nanopore for Detecting Individual Biopolymers (2009)

Solid-state nanopores have been fabricated and used to characterize single DNA and protein molecules. Here we describe the details on how these nanopores were fabricated and characterized, the nanopore sensing system setup, and protocols of using these nanopores to characterize DNA and protein molecules.
High-power femtosecond fiber-feedback optical parametric oscillator based on periodically poled stoichiometric LiTaO_3 (2004)

We demonstrate a synchronously pumped high-gain optical parametric oscillator with feedback through a fiber, using a passively mode-locked Yb:YAG thin-disk laser as a pump source. We obtain as much as 19-W average signal power at a wavelength of 1.45 microm in 840-fs pulses and 7.8 W of idler power at 3.57 microm. The repetition rate of the pulses is 56 MHz, and the transverse beam quality of the generated signal is M2 < 1.6.
Minority-carrier transport in InGaAsSb thermophotovoltaic diodes (1997)

Uncoated InGaAsSb/GaSb thermophotovoltaic (TPV) diodes with 0.56 eV (2.2 {micro}m) bandgaps exhibit external quantum efficiencies of 59% at 2 {micro}m. The devices have electron diffusion lengths as long as 29 {micro}m in 8-{micro}m-wide p-InGaAsSb layers and hole diffusion lengths of 3 {micro}m in 6-{micro}m-wide n-InGaAsSb layers. The electron and hole diffusion lengths appear to increase with increasing p- and n-layer widths. At 632.8 nm the internal quantum efficiencies of diodes with 1- to 8-{micro}m-wide p-layers are above 89% and are independent of the p-layer width, indicating long electron diffusion lengths. InGaAsSb has, therefore, excellent minority carrier transport properties that are well suited to efficient TPV diode operation. The structures were grown by molecular-beam epitaxy.
Data from <i>KRAS</i> Codon 12 and 13 Mutations in Relation to Disease-Free Survival in <i>BRAF</i>–Wild-Type Stage III Colon Cancers from an Adjuvant Chemotherapy Trial (N0147 Alliance) (2023)

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; We examined the prognostic impact of specific &lt;i&gt;KRAS&lt;/i&gt; mutations in patients with stage III colon adenocarcinoma receiving adjuvant FOLFOX alone or combined with cetuximab in a phase III trial (N0147). Analysis was restricted to &lt;i&gt;BRAF&lt;/i&gt;–wild-type tumors, because &lt;i&gt;BRAF&lt;/i&gt; mutation was associated with poor prognosis, and &lt;i&gt;BRAF&lt;/i&gt; and &lt;i&gt;KRAS&lt;/i&gt; mutations are mutually exclusive.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; The seven most common &lt;i&gt;KRAS&lt;/i&gt; mutations in codon 12 and codon 13 were examined in 2,478 &lt;i&gt;BRAF&lt;/i&gt;–wild-type tumors. Because &lt;i&gt;KRAS&lt;/i&gt; mutations in codon 12 (&lt;i&gt;n&lt;/i&gt; = 779) or 13 (&lt;i&gt;n&lt;/i&gt; = 220) were not predictive of adjuvant cetuximab benefit, study arms were pooled for analysis. Disease-free survival (DFS) was evaluated by HRs using Cox models.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt;&lt;i&gt;KRAS&lt;/i&gt; mutations in codon 12 (multivariate HR, 1.52; 95% confidence interval, CI, 1.28–1.80; &lt;i&gt;P&lt;/i&gt; &lt; 0.0001) or codon 13 (multivariate HR, 1.36; 95% CI, 1.04–1.77; &lt;i&gt;P&lt;/i&gt; = 0.0248) were significantly associated with shorter DFS compared with patients with wild-type &lt;i&gt;KRAS&lt;/i&gt;/&lt;i&gt;BRAF&lt;/i&gt; tumors, independent of covariates. &lt;i&gt;KRAS&lt;/i&gt; codon 12 mutations were independently associated with proficient mismatch repair (&lt;i&gt;P&lt;/i&gt; &lt; 0.0001), proximal tumor site (&lt;i&gt;P&lt;/i&gt; &lt; 0.0001), low grade, age, and sex, whereas codon 13 mutations were associated with proximal site (&lt;i&gt;P&lt;/i&gt; &lt; 0.0001).&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusion:&lt;/b&gt;&lt;i&gt;KRAS&lt;/i&gt; mutations in either codon 12 or 13 are associated with inferior survival in patients with resected stage III colon cancer. These data highlight the importance of accurate molecular characterization and the significant role of &lt;i&gt;KRAS&lt;/i&gt; mutations in both codons in the progression of this malignancy in the adjuvant setting. &lt;i&gt;Clin Cancer Res; 20(11); 3033–43. ©2014 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;
Dry Care Versus Antiseptics for Umbilical Cord Care: A Cluster Randomized Trial (2016)

Dry cord was noninferior to the use of antiseptics in preventing omphalitis in full-term newborns in a developed country. Antiseptic use in umbilical cord care is therefore unnecessary, constraining, and expensive in high-income countries and may be replaced by dry care.
Inhibition of matrix metalloproteinase‐2 secretion and invasion by human ovarian cancer cell line SK‐OV‐3 with lysine, proline, arginine, ascorbic acid and green tea extract (2006)

The combination of lysine, proline, arginine, ascorbic acid and green tea extract tested inhibited critical steps in cancer development and spread, such as MMP expression and invasion, indicating its potential as a treatment modality against ovarian cancer.
An investigation of hydrogen bonding in amides using Raman spectroscopy (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAn investigation of hydrogen bonding in amides using Raman spectroscopyNancy E. Triggs and James J. ValentiniCite this: J. Phys. Chem. 1992, 96, 17, 6922–6931Publication Date (Print):August 1, 1992Publication History Published online1 May 2002Published inissue 1 August 1992https://pubs.acs.org/doi/10.1021/j100196a014https://doi.org/10.1021/j100196a014research-articleACS PublicationsRequest reuse permissionsArticle Views1297Altmetric-Citations66LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
New endoscopic treatment for superficial carcinoma of borderline lesions between the cervical esophagus and hypopharynx. (2013)

107 Background: Early diagnosis and early treatment are the best ways to improve cancer patient prognoses. We developed ELPS (endoscopic laryngo-pharyngeal surgery) as an endoscopic treatment for superficial pharyngeal carcinoma. ELPS is transoral endoscopic surgery for laryngeal cancer. After lifting the larynx using the laryngoscope, the endoscopist inserts endoscope and the operator inserts forceps and electric device transorally, and resects superficial phayngeal carcinoma. However, ELPS has not been applied for cervical esophagus carcinoma because of the narrow working space. We developed a hybrid endoscopic surgery (ESD+ELPS) for borderline lesions between the cervical esophagus and hypopharynx. The purpose of this study was to examine the usefulness and effectiveness of endoscopic treatment for superficial carcinoma of the hypopharynx and cervical esophagus. Methods: Hybrid endoscopic surgery (ESD and ELPS) was performed on 8 lesions, which involved both the hypopharynx and cervical esophagus. Results: Six of eight patients had esophageal cancer treatments in their past histories, two for ESD, two for esophagectomy and two for chemoradiation. All lesions were completely resected. The complications of this procedure were laryngeal edema for three patients, which required overnight intubation, and stenosis of cervical esophagus for two patients, which required endoscopic dilation more than 10 times. There were no long term complications in all patients. Conclusions: The results indicated the usefulness and effectiveness of hybrid endoscopic treatment (ELPS+ESD) for superficial carcinoma of borderline lesion between the cervical esophagus and hypopharynx.
Conceptual design of a deposition system for uniform and combinatorial synthesis of multinary thin-film materials via open-boat physical-vapor deposition (2006)

Conventional flux-distribution formulas for rotating and static substrates are used to develop a method for combinatorial physical-vapor deposition. With this method, a single deposition system may be used, without modification, to deposit either highly uniform or graded-composition thin-film materials. This is accomplished through appropriate automated sequencing of source shuttersand substrate rotation. A constrained-composition parametrization is introduced, whichdetermines relative deposition times for the film constituents with and without substraterotation. The combinatorial deposition scheme developed here is applicable to binary, ternary,or quaternary phase systems. Examples are considered for the pseudoquaternary CuInSe2–AgInSe2–CuGaSe2–AgGaSe2 chalcopyrite materials system, which has relevance to thin-film photovoltaics.
User-Defined Functions for HDF5 (2021)

Scientific datasets are known for their challenging storage demands and the associated processing pipelines that transform their information. Some of those processing tasks include filtering, cleansing, aggregation, normalization, and data format translation -- all of which generate even more data. In this paper, we present an infrastructure for the HDF5 file format that enables dataset values to be populated on the fly: task-related scripts can be attached into HDF5 files and only execute when the dataset is read by an application. We provide details on the software architecture that supports user-defined functions (UDFs) and how it integrates with hardware accelerators and computational storage. Moreover, we describe the built-in security model that limits the system resources a UDF can access. Last, we present several use cases that show how UDFs can be used to extend scientific datasets in ways that go beyond the original scope of this work.
A reassessment of the use of chromosome inversions for insect control (1975)

Journal Article A reassessment of the use of chromosome inversions for insect control Get access A. S. ROBINSON A. S. ROBINSON Association Euratom Institute for Atomic Sciences in AgricultureWageningen, The Netherlands Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Heredity, Volume 66, Issue 1, January 1975, Pages 35–37, https://doi.org/10.1093/oxfordjournals.jhered.a108570 Published: 01 January 1975
Analysis of Correlation between an Accelerometer-Based Algorithm for Detecting Parkinsonian Gait and UPDRS Subscales (2017)

The correlation achieved by the algorithm with the UPDRS-III scale suggests that this algorithm might be a useful tool for monitoring patients with Parkinson's disease and motor fluctuations.
4-Aminopyridine Catalyzed Direct and Regioselective Acylation of N-Tosylhydrazide (2009)

An efficient and simple method for selective acylation of either one of two nitrogen atoms of tosylhydrazide was developed. The selectivity was drastically controlled by a catalytic amount of 4-aminopyridine or 4-(dimethylamino)pyridine with common acylating agents. The nitrogen atom masked with a tosyl group was acylated in the presence of 4-aminopyridine, whereas the primary nitrogen atom was acylated in the absence of 4-aminopyridine.