gebhart/patrepeval huggingface dataset:
Synthesis, antifungal and antibacterial activity for novel amide derivatives containing a triazole moiety (2013)

A series of novel amide derivatives containing 1,2,4-triazole moiety were synthesized through the reaction of intermediate 3 with different acyl chlorides and anhydrous potassium carbonates in anhydrous tetrahydrofuran at 50°C, using 2,4-dichloroacetophenoneas as a starting material. The title compounds exhibited high inhibitory effects against P. sasakii, R. solanacearum, and G. azeae.
Influence of Chopped Fibre Length on the Mechanical and Thermal Properties of Silk Fibre-Reinforced Poly(Butylene Succinate) Biocomposites (2005)

The influence of chopped fibre length on the mechanical and thermal properties of silk fibre ( Bombix mori) reinforced poly(butylene succinate) (PBS) biocomposites has been investigated in terms of tensile and flexural properties, thermal stability, thermal expansion, and dynamic mechanical properties. The chopped fibre lengths studied were 3.2 mm, 6.4 mm, 12.7 mm, and 25.4 mm. The results demonstrate that chopped silk fibres play an effective role in improving the mechanical properties of PBS in the present system. At a fixed fibre loading of 40 wt%, the tensile strength and modulus of the PBS control were improved by 69% and 228%, respectively, in comparison with those of the biocomposite reinforced with 25.4 mm silk fibres. The flexural strength and modulus of PBS were also greatly improved by 167% and 323%, respectively. The thermal properties of PBS resin increased when incorporating chopped silk fibres in the composite matrix. The biocomposites had much lower linear coefficient of thermal expansion (CTE) values and higher storage moduli than the PBS controls above the glass transition region, especially with reinforcing silk fibres of 25.4 mm long.
WE‐DE‐207B‐01: Optimization for Contrast‐Enhanced Spectral Mammography Based On Photon‐Counting Detectors (2016)

Purpose: To investigate the feasibility of optimizing the imaging parameters for contrast‐enhanced spectral mammography based on Si strip photon‐counting detectors. Methods: A computer simulation model using polyenergetic spectra from a tungsten anode x‐ray tube and a Si‐based photon‐counting detector was evaluated for contrast‐enhanced spectral mammography. The simulation traces the emission of photons from the x‐ray source, attenuation through the breast and subsequent absorption in the detector. The breast was modeled as a mixture of adipose and mammary gland tissues with a breast density of 30%. A 4 mm iodine signal with a concentration of 4 mg/ml was used to simulate the enhancement of a lesion. Quantum efficiency of the detector was calculated based on the effective attenuation length in the Si strips. The figure‐of‐merit (FOM), which was defined as the decomposed iodine signal‐to‐noise ratio (SNR) with respect to the square root of the mean glandular dose (MGD), was chosen to optimize the imaging parameters, in terms of beam energy, splitting energy, and pre‐filtrations for breast of various thicknesses and densities. Results: The optimal imaging parameters, which lead to the highest FOM, were found at a beam energy of 45 kVp with a splitting energy at 34 keV for an averaged breast thickness of 4 cm with a standard 0.75 mm Al pre‐filtration. The optimal tube voltage varied slightly from 46 to 44 kVp as the breast thickness increases from 2 to 8 cm. The optimal tube voltage decreased to 42 kVp when the Al pre‐filtration was increased to 3 mm. Conclusion: This simulation study predicted the optimal imaging parameters for application of photon‐counting spectral mammography to contrast‐enhanced imaging. The simulation results laid the ground work for future phantom and clinical studies. Grant funding from Philips Medical Systems.
Abstract 1929: Mutations in the Cardiac L-Type Calcium Channel Associated With Four Sudden Cardiac Death Syndromes (2009)

In this study, we investigated the potential therapeutic effects of tofisopam, a 2,3-benzodiazepine derivative anxiolytic, on cognitive deficits in rats with scopolamine-induced amnesia. Cognitive performance of the rats was investigated by using the Morris water maze and passive avoidance tests. Changes in motor activity were assessed by using the activity cage and Rota-rod tests and then morphological changes in the hippocampus were assessed via immunohistochemical stainings. The results indicated that scopolamine impaired learning and memory parameters in rats. Worsened cognitive performance, neuronal loss, and decreased hippocampal synaptophysin, Ki-67, and glial fibrillary acidic protein density were observed. Tofisopam administration at a dose of 50 mg/kg for seven days improved the impaired cognitive performance, enhanced the attenuated synaptic transmission in the hippocampus, increased proliferation in subgranular zones, and improved the decrease in astrocytes in amnesic rats. These findings point out the anti-amnesic effects of tofisopam with concomitant improvements in the hippocampal synaptogenesis, neurogenesis, and glial plasticity, for the first time. Presented beneficial effects of tofisopam on cognitive dysfunctions may have a notable clinical value considering the fact that one of the most important side effects of 1,4-benzodiazepines, which are classical anxiolytic drugs, is amnesia. However, these preclinical results need to be confirmed with further clinical studies, first.
Émotions et apprentissages. Une approche comparée des pratiques pédagogiques des professionnels en milieu préscolaire dans quatre pays européens (2022)

L’article rend compte de la recherche-action pour le projet erasmus+ Development and Run-Test of an Educational Affective Model (DREAM, 2016-2019) dans 4 pays Européens. Celui-ci vise à questionner les approches permettant d’« éduquer » aux émotions, afin de proposer une approche pédagogique européenne innovante, centrée sur les manifestations émotionnelles entre professionnelles de l’éducation et enfants en école maternelle ou jardins d’enfants (3-6 ans).
Simultaneous Identification of Multiple Driver Pathways in Cancer (2013)

Distinguishing the somatic mutations responsible for cancer (driver mutations) from random, passenger mutations is a key challenge in cancer genomics. Driver mutations generally target cellular signaling and regulatory pathways consisting of multiple genes. This heterogeneity complicates the identification of driver mutations by their recurrence across samples, as different combinations of mutations in driver pathways are observed in different samples. We introduce the Multi-Dendrix algorithm for the simultaneous identification of multiple driver pathways de novo in somatic mutation data from a cohort of cancer samples. The algorithm relies on two combinatorial properties of mutations in a driver pathway: high coverage and mutual exclusivity. We derive an integer linear program that finds set of mutations exhibiting these properties. We apply Multi-Dendrix to somatic mutations from glioblastoma, breast cancer, and lung cancer samples. Multi-Dendrix identifies sets of mutations in genes that overlap with known pathways - including Rb, p53, PI(3)K, and cell cycle pathways - and also novel sets of mutually exclusive mutations, including mutations in several transcription factors or other genes involved in transcriptional regulation. These sets are discovered directly from mutation data with no prior knowledge of pathways or gene interactions. We show that Multi-Dendrix outperforms other algorithms for identifying combinations of mutations and is also orders of magnitude faster on genome-scale data. Software available at: http://compbio.cs.brown.edu/software.
Ontogeny of Isolated Ultrasound Markers for Fetal Aneuploidy (1999)

Isolated ultrasound markers for aneuploidy are transient and may disappear later on in gestation. Transvaginal sonography at 14-16 weeks of gestation appears to provide the best time window for detection of markers for fetal abnormal karyotype.
ChemInform Abstract: Unexpected Chemoselectivity in the Rhodium‐Catalyzed Transfer Hydrogenation of α,β‐Unsaturated Ketones in Ionic Liquids. (2010)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
An optimal algorithm for the all-nearest-neighbors problem (1986)

Given a set V of n points in k-dimensional space, and an Lq-metric (Minkowski metric), the All-Nearest-Neighbors problem is defined as follows: For each point p in V, find all those points in V-{p} that are closest to p under the distance metric Lq. We give an O(nlogn) algorithm for the All-Nearest-Neighbors problem, for fixed dimension k and fixed metric Lq. Since there is an Ω(n logn) lower bound, in the algebraic decision tree model of computation, on the time complexity of any algorithm that solves the All-Nearest-Neighbors problem (for k = 1), the running time of our algorithm is optimal upto a constant.
X-ray Image Subtraction by Digital Means (1973)

A conventional method of removing unwanted background information from radiographic images is to use photographic techniques. An alternative approach is the digital processing of x-ray difference images. This approach offers the advantage over photographic methods in that it permits the performance of nonlinear operations, such as compensation for film characteristics, thus offering greater flexibility in the presentation of x-ray images and greater reliability in their interpretation. This paper describes the features and implementation of a new digital approach and presents experimental results obtained from processing two sets of angiograms.
Table. S1 from <i>Hes1</i> Is Essential in Proliferating Ductal Cell–Mediated Development of Intrahepatic Cholangiocarcinoma (2023)

&lt;p&gt;Primer sequences used for real-time PCR.&lt;/p&gt;
A Facile Synthesis of DNA-Magnetic-Fluorescent Composite Particles (2012)

A simple and convenient method to make a novel material of DNA-coated magnetic-fluorescent composite particles was presented in this article. Hydrothermal synthesis was used for obtaining Fe3O4 magnetic nanoparticles. After modified by oleic acid, the nanoparticles were coated by the macromolecular shell, which came form the polymerization of ethyleneglycol dimethacrylate and methacrylic acid. With the help of ethylenediamine as linker molecules and the condensation effect of ethyl (dimethylaminopropyl) – carbodiimide and N-Hydroxysuccinimide (EDC/NHS) reaction system, salmon DNA were linked to the surface of the shell. After labeling a fluorescent dye Syber Green Ⅰ®, the magnetic-fluorescent composite particles were produced.
DISCUSSION ON THE WORKING FLUID ON INTERNAL-COMBUSTION ENGINES. (INCLUDES CORRIGENDUM ON P iv). (1934)

Keywords WORKING, FLUIDS, INTERNAL, COMBUSTION, ENGINES, EXPERIMENTS, EXPLOSIONS, VESSELS, SPECIFIC, HEAT, INCOMPLETE, TEMPERATURE, MIXTURES, THERMAL, EFFICIENCY, ENERGY, FUEL, LOSS, SPEED, LATENT, GAS... Show All
Wireless TCP proposals with proxy servers in the GPRS network (2003)

The General Packet Radio Service (GPRS) system will offer to the users an easy access to Internet applications which work with the TCP protocol. We analyse by means of simulations the performance in the GPRS network of the following wireless TCP proposals that use a proxy server: the Snoop protocol and the Split mechanism. We also describe the impact of the GPRS LLC layer in acknowledged mode in the TCP end-to-end throughput. Unlike previous research we consider two scenarios for the GPRS radio interface: one with several users present in the system, and the other with only one user in it.
Applying Random Forests To Identify Biomarker Panels in Serum 2D-DIGE Data for the Detection and Staging of Prostate Cancer (2010)

In recent years, Prostate Specific Antigen (PSA) testing is widespread and has been associated with deceased mortality rates; however, this testing has raised concerns of overdiagnosis and overtreatment. It is clear that additional biomarkers are required. To identify these biomarkers, we have undertaken proteomics and metabolomics expression profiles of serum samples from BPH, Gleason score 5 and 7 using two-dimensional difference in gel electrophoresis (2D-DIGE) and nuclear magnetic resonance spectroscopy (NMR). Panels of serum protein biomarkers were identified by applying Random Forests to the 2D-DIGE data. The evaluation of selected biomarker panels has shown that they can provide higher prediction accuracy than the current diagnostic standard. With careful validation of these serum biomarker panels, these panels may potentially help to reduce unnecessary invasive diagnostic procedures and more accurately direct the urologist to curative surgery.
iFlowGAN: An Invertible Flow-based Generative Adversarial Network For Unsupervised Image-to-Image Translation (2021)

We propose iFlowGAN that learns an invertible flow (a sequence of invertible mappings) via adversarial learning and exploit it to transform a source distribution into a target distribution for unsupervised image-to-image translation. Existing GAN-based generative model such as CycleGAN [1], StarGAN [2], AGGAN [3] and CyCADA [4] needs to learn a highly under-constraint forward mapping F: X → Y from a source domain X to a target domain Y. Researchers do this by assuming there is a backward mapping B: Y → X such that x and y are fixed points of the composite functions B °F and F °B. Inspired by zero-order reverse filtering [5], we (1) understand F via contraction mappings on a metric space; (2) provide a simple yet effective algorithm to present B via the parameters of F in light of Banach fixed point theorem; (3) provide a Lipschitz-regularized network which indicates a general approach to compose the inverse for arbitrary Lipschitz-regularized networks via Banach fixed point theorem. This network is useful for image-to-image translation tasks because it could save the memory for the weights of B. Although memory can also be saved by directly coupling the weights of the forward and backward mappings, the performance of the image-to-image translation network degrades significantly. This explains why current GAN-based generative models including CycleGAN must take different parameters to compose the forward and backward mappings instead of employing the same weights to build both mappings. Taking advantage of the Lipschitz-regularized network, we not only build iFlowGAN to solve the redundancy shortcoming of CycleGAN but also assemble the corresponding iFlowGAN versions of StarGAN, AGGAN and CyCADA without breaking their network architectures. Extensive experiments show that the iFlowGAN version could produce comparable results of the original implementation while saving half parameters.
Development and implementation of a biomanipulation system with magnetic-driven microrobots (2013)

Recently, biomanipulation microrobots have attracted much attention in both academia and industry since they have become a promising tool to perform the practical biological micromanipulation tasks. In this field, biological micromanipulation on micro-fluidic chip emerge as a new focus since it can be used to improve the biomanipulation efficiency and stability. This study aims to develop a micromanipulation system with magnetic driven microrobots to implement the practical biomanipulations on a micro-fluidic chip. A novel flexure-based micromanipulator with large-workspace and micro/nano scale motion accuracy is proposed in this paper. After a series of mechanism optimal designs and analytic modeling, the positioning performance of the micromanipulators are evaluated by using the ANSYS Workbench Platform. After the mechanism fabrication, with the consideration of rate-dependent hysteresis effect inherent in piezoelectric ceramics (PZT) actuators, a novel hybrid visual servo control (HVSC) strategy combining with the Extreme Learning Machine (ELM) and the Artificial Neural Network (ANN) is proposed. Afterwards, a series of practical biomanipulation experiments are successfully implemented by using the designed control strategy. Both theoretical analysis and visual tracking results uniformly demonstrate the satisfactory performance of the developed system.
A New Current Phasor-Controlled ZVS Twin Half-Bridge High-Frequency Resonant Inverter for Induction Heating (2013)

A novel soft-switching high-frequency (HF) resonant (HF-R) inverter for induction heating (IH) applications is presented in this paper. By adopting the current phasor control of changing a phase shift (PS) angle between two half-bridge inverter units, the IH load resonant current can be regulated continuously under the condition of wide-range soft-switching operations. In addition to this, the dual-mode power regulation scheme-based PS angle control and asymmetrical pulsewidth modulation in one inverter unit is proposed for improving the efficiency in low output power settings. The essential performances on the output power regulation and soft-switching operations are demonstrated in an experiment using its 1-kW 60-kHz HF-R inverter prototype, and then, the topological validity is evaluated from a practical point of view.
Pilot-scale evaluation of LIMB (Limestone Injection Multistage Burner) technology. Final report, July 1982-July 1985 (1987)

This report gives results of pilot-scale studies of sulfur capture in the EPA's Limestone Injection Multistage Burner (LIMB) process and the effect of LIMB on particulate properties and electrostatic precipitator (ESP) performance. The sulfur-capture studies showed that hydrated lime was generally superior to limestone as a sorbent for in-furnace sulfur removal. For both sorbents, downstream injection was found to be preferable over near-flame injection. With hydrated lime, the optimum injection temperature was found to be about 1200 C, where utilizations as high as 30% were achieved. The injection of either sorbent resulted in a large increase in the electrical resistivity of the ash, which could severely impact ESP performance. Laboratory and pilot-scale studies showed that the resistivity increase could be offset by flue-gas conditioning using sulfur trioxide (SO/sub 3/) or water vapor. With limestone injection, acceptable resistivity levels were restored by the injection of 30 ppm of SO/sub 3/.
Understanding Risk Factors for Neonatal Herpes Can Help Prevent It (2003)

The risk for transmitting herpes simplex virus (HSV) from mother to infant is poorly quantified, as is the effect of maternal antibodies to HSV type 1
Gigabit Optical Interconnects: System and Component Analysis, Design and Development (1994)

This report describes the results of experiments performed in various areas of technology required to develop gigabit optical interconnects for communication at 1.3 micrometer wavelength. First, we will summarize the analysis of optical correlation switches (i.e. optical AND gates) for use in time-division optical interconnects. Next, we describe the design and characterization of an all-optical, 30db contrast ratio GaAlInAs multiple quantum well asymmetric reflection modulator. Then, we comment on the characterization of polarization-dependent, strained-layer InGaAs/GaAs materials useful for light emitters and modulators. Finally, we report on the development of an optically transparent ATM packet switch testbed operating at 1.24416 Gbit/ s. This work is a continuation of in-house efforts begun under 62702F, JON 4600P201 and summarized in RL-TR-91-398.
ChemInform Abstract: Preparation of 2H‐5,6‐Dihydroselenines Using α‐Alkoxy Carbonylselenoacetamide. (2015)

Abstract and α,β‐unsaturated ketones
Configuration at the 2-position of oxazolidines derived from l-ephedrine and p-bromobenzaldehyde. An x-ray structure redetermination (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTConfiguration at the 2-position of oxazolidines derived from l-ephedrine and p-bromobenzaldehyde. An x-ray structure redeterminationGeorge Just, Pierre Potvin, and Peter UggowitzerCite this: J. Org. Chem. 1983, 48, 17, 2923–2924Publication Date (Print):August 1, 1983Publication History Published online1 May 2002Published inissue 1 August 1983https://pubs.acs.org/doi/10.1021/jo00165a027https://doi.org/10.1021/jo00165a027research-articleACS PublicationsRequest reuse permissionsArticle Views107Altmetric-Citations24LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Aspirin for primary thrombosis prevention in the antiphospholipid syndrome: A randomized, double‐blind, placebo‐controlled trial in asymptomatic antiphospholipid antibody–positive individuals (2007)

Our results suggest that asymptomatic, persistently aPL-positive individuals do not benefit from low-dose aspirin for primary thrombosis prophylaxis, have a low overall annual incidence rate of acute thrombosis, and develop vascular events when additional thrombosis risk factors are present.
Structure, Ionic Conductivity, and Dielectric Properties of Li-Rich Garnet-type Li5+2xLa3Ta2–xSmxO12 (0 ≤ x ≤ 0.55) and Their Chemical Stability (2017)

Lithium garnet oxides are considered as very promising solid electrolyte candidates for all-solid-state lithium ion batteries (SSLiBs). In this work, we present a cubic garnet-type Li<sub>5+2x</sub>La<sub>3</sub>Ta<sub>2-x</sub>Sm<sub>x</sub>O<sub>12</sub> (0 ≤ x ≤ 0.55) system as a potential electrolyte for SSLiBs. Powder X-ray diffraction (PXRD) and scanning electron microscopy (SEM) were employed to investigate the structural stability of Li<sub>5+2x</sub>La<sub>3</sub>Ta<sub>2-x</sub>Sm<sub>x</sub>O<sub>12</sub>. The results from PXRD and SEM suggested structural and morphological transformation as a function of dopant concentration. In addition to Li-ion transport in Li<sub>5+2x</sub>La<sub>3</sub>Ta<sub>2-x</sub>Sm<sub>x</sub>O<sub>12</sub>, the dielectric properties were also investigated in the light of electron energy loss functions, which showed some surface energy loss and negligible volume energy loss for the studied garnets. Surface and volume energy loss functions of a mixed conducting LiCoO<sub>2</sub> was studied for comparison. The long-term chemical stability of one of members, Li<sub>5.3</sub>La<sub>3</sub>Ta<sub>1.85</sub>Sm<sub>0.15</sub>O<sub>12</sub>, was performed on aged sample using PXRD, SEM, and thermogravimetric analysis.
Radiation characteristics of flexible reconfigurable antenna with curved cylindrical configurations (2016)

In this paper, a flexible reconfigurable antenna mounted on curved cylindrical configurations is presented. The proposed design is based on a folded slot antenna printed on a flexible Polyethylene Terephthalate (PET) substrate. One PIN-diode is incorporated to the antenna surface to make it reconfigurable in terms of its resonant frequencies and polarizations. The impact of curved cylindrical geometries, such as circumferential and axial configurations, on the antenna radiation characteristics is discussed.