gebhart/patrepeval huggingface dataset:
Advances in Molten Oxide Electrolysis for the Production of Oxygen and Metals from Lunar Regolith (2008)

As part of an In-Situ Resource Utilization infrastructure to sustain long term-human presence on the lunar surface, the production of oxygen and metals by electrolysis of lunar regolith has been the subject of major scrutiny. There is a reasonably large body of literature characterizing the candidate solvent electrolytes, including ionic liquids, molten salts, fluxed oxides, and pure molten regolith itself. In the light of this information and in consideration of available electrolytic technologies, the authors have determined that direct molten oxide electrolysis at temperatures of approx 1600 C is the most promising avenue for further development. Results from ongoing studies as well as those of previous workers will be presented. Topics include materials selection and testing, electrode stability, gas capture and analysis, and cell operation during feeding and tapping.
Granulocyte-macrophage colony-stimulating factor is a stimulant of platelet-activating factor and superoxide anion generation by human neutrophils. (1991)

Human granulocyte-macrophage colony-stimulating factor (GM-CSF) was studied for its ability to stimulate the synthesis and release of the inflammatory mediator platelet-activating factor (PAF) from human neutrophils as measured by bioassay and incorporation of [3H]acetate into PAF. GM-CSF stimulated the synthesis but not the release of PAF from neutrophils. PAF synthesis took place in a time- and concentration-dependent manner, was dependent on a pertussis toxin-sensitive G protein and could be inhibited by antibodies to GM-CSF. On the other hand, pre-incubation of neutrophils with GM-CSF followed by stimulation with the bacterial tripeptide formylmethionylleucylphenylalanine caused PAF synthesis and release. The effect of GM-CSF was qualitative and not simply the result of larger amounts of PAF being synthesized since similar amounts were generated in response to the calcium ionophore A23187 but no released PAF could be detected. In functional studies GM-CSF stimulated superoxide anion generation from neutrophils with a time and dose relationship that paralleled PAF synthesis. In addition, the serine protease inhibitor L-1-tosylamide-2-phenylethyl chloromethyl ketone, which inhibits PAF synthesis, reduced PAF accumulation as well as superoxide generation, raising the possibility of a causal relationship between cell-associated PAF and cell activation. These results identify PAF as a direct product of GM-CSF stimulation in neutrophils where it may play a role in signal transduction and demonstrate that PAF is released only after subsequent neutrophil stimulation. The selective release of PAF may play a role in regulating and amplifying the inflammatory response.
HILIC UPLC/ QTof MS Method Development for the Quantification ofAGEs Inhibitors - Trouble Shooting Protocol (2023)

Reporting those findings can be considered beneficial while bringing an insightful notion about critical factors and potential interferences. Therefore, some conclusion and ideas can be drawn from these trouble-shooting questions, which might help other researchers to develop more reliable bioanalytical methods, or to raise their awareness of stumbling blocks along the way.
Bioactivity of diopside ceramic in human parotid saliva (2005)

Diopside ceramic pellets with a nominal composition of 55.5 wt % SiO(2)-25.9 wt % CaO-18.0 wt % MgO were soaked in human parotid saliva (HPS) over different time intervals, to investigate the behavior of the material in a natural medium of high protein content. The results showed the formation of a hydroxyapatite (HA)-like layer on the surface of the ceramic, and suggested that the mechanism of HA-like layer formation in saliva was similar to that showed in vitro test by other silica-based materials. The HA-like layer formed at the interface was found to be compact, continuous, and composed of many small crystallites with ultrastructure similar to that of natural cortical bone and dentine. The study concluded that the high pH conditions (9.8) existing right at the ceramic/human parotid saliva interface promoted HA-like phase precipitation. At this stage of the study, it is possible to suggest that the diopside ceramic could be of interest in specific periodontal applications for bone restorative purposes. Morphology, structure, and composition of the interfacial reaction product were examined by Scanning and Transmission Electron Microscopy techniques (SEM and TEM), combined with Energy Dispersive X-say Spectroscopy (EDS). Changes in ionic concentrations were measured using Inductively Coupled Plasma Atomic Emission Spectroscopy (ICP-AES), while the pH right at the interface of diopside/PHS were determined with an Ion Sensitive Field Effect Transistor (ISFET-Meter) instruments.
Plasma metabolome cold exposure (2021)

Metabolome - full list of metabolites before and after acute cold exposure.
Human chorionic gonadotropin. VII. Preparation and immunocharacteristics of carboxyl-terminal peptides of the .BETA.-subunit of human chorionic gonadotropin. (1982)

Various carboxyl-terminal peptides of hCG-β were prepared from the corresponding blocked peptides by TFA treatment followed by hydrogenation. The prepared peptides were tested for inhibitory action on the binding between 125I-hCG and the antiserum against the carboxyl-terminal portion of hCG-β. The results suggest that an antigenic site of this antiserum may exist around the amino-terminal portion of the carboxylterminal hexadecapeptide.
Direct interaction of the Fanconi anaemia protein FANCG with BRCA2/FANCD1 (2003)

Fanconi anaemia (FA) is an autosomal recessive genetic disorder characterized by progressive bone marrow failure, multiple congenital abnormalities, and an increased risk of cancer. FA cells are characterized by chromosomal instability and hypersensitivity to DNA interstrand crosslinking agents. At least eight complementation groups exist (FA-A to G), and the genes for all of these except FA-B have been cloned. Functional linkage between the FA pathway and genes involved in susceptibility to breast cancer has been demonstrated by the interaction of the FANCA and FANCD2 proteins with BRCA1, and the discovery that the FANCD1 gene is identical to BRCA2. Here we have used the yeast two-hybrid system to test for direct interaction between BRCA2 or its effector RAD51 and the FANCA, FANCC and FANCG proteins. We found that FANCG was capable of binding to two separate sites in the BRCA2 protein, located either side of the BRC repeats. Furthermore, FANCG could be co-immunoprecipitated with BRCA2 from human cells, and FANCG co-localized in nuclear foci with both BRCA2 and RAD51 following DNA damage with mitomycin C. These results demonstrate that BRCA2 is directly connected to a pathway that is deficient in interstrand crosslink repair, and that at least one other FA protein is closely associated with the homologous recombination DNA repair machinery.
Influence of Intermolecular Interactions on the Structure of Copper Phthalocyanine Layers on Passivated Semiconductor Surfaces (2010)

The surface structures of copper phthalocyanine (CuPc) thin films deposited on sulphur-passivated and plane perylene-3,4,9,10-tetracarboxylic dianhydride (PTCDA)-covered InAs(100) surfaces have been studied by low energy electron diffraction (LEED) and van der Waals (vdW) intermolecular interaction energy calculations. The annealing to <TEX>$300^{\circ}C$</TEX> and <TEX>$450^{\circ}C$</TEX> of <TEX>$(NH_4)_2S_x$</TEX>-treated InAs(100) substrates produces a (<TEX>$1{\times}1$</TEX>) and (<TEX>$2{\times}1$</TEX>) S-passivated surface respectively. The CuPc deposition onto the PTCDA-covered InAs(100) surface leads to a ring-like diffraction pattern, indicating that the 2D ordered overlayer exists and the structure is dominantly determined by the intermolecular interactions rather than substrate-molecule interactions. However, no ordered LEED patterns were observed for the CuPc on S-passivated InAs(100) surface. The intermolecular interaction energy calculations have been carried out to rationalise this structural difference. In the case of CuPc unit cells on PTCDA layer, the planar layered CuPc structure is more stable than the <TEX>$\alpha$</TEX>-herringbone structure, consistent with the experimental LEED results. For CuPc unit cells on a S-(<TEX>$1{\times}1$</TEX>) layer, however, the <TEX>$\alpha$</TEX>-herringbone structure is more stable than the planar layered structure, consistent with the absence of diffraction pattern. The results show that the lattice structure during the initial stages of thin film growth is influenced strongly by the intermolecular interactions at the interface.
Psychosocial Factors in Chronic Wound Patients (2023)

Background/Objective: Chronic wound (CW) represents a major burden on the individual patients who are typically challenged with many underlying health related complications. Stress is now recognized as a universal premorbid factor associated with many risk factors of various chronic diseases. This study utilized socio-demographic data of CW patients and analyzed it against salivary cortisol, a known marker of psychosocial stress. Methods: CW patients were recruited under IRB approved protocol of Indiana University (ClinicalTrials.gov Identifier# NCT03793062). Morning saliva samples were analyzed from 11 patients with CW (56.4±2.8 years). The Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder (GAD-7) assessment were used as screening tools as well as measures of symptom severity for depression (PHQ-9) and different types of anxiety (GAD-7). Human salivary cortisol was measured by ELISA. Results: The salivary cortisol concentration for CW patients were as follows: those with minimal depression (PHQ-9 score ≤4) had 2.2±0.5 ng/mL; those affected by moderate severe depression (PHQ-9 score &gt;4) showed 1.3±0.3 ng/mL; those with minimal anxiety (GAD-7 score ≤4) was 1.8±0.5 ng/mL; and those with mild to severe anxiety (GAD-7 score &gt;4) had 1.6±0.3 ng/mL. Comparison across race showed that the African American CW patients had higher (2.8±0.5 ng/mL) salivary cortisol levels compared to white CW patients (1.5±0.3 ng/mL). Conclusion and Impact: These preliminary study results indicated that although higher scales of depression and anxiety do not seem to increase salivary cortisol, it is likely that African American CW patients are subject to higher psychosocial stress compared to Caucasian CW patients. The study of a larger sample size is warranted.
Photocatalytic equipment with nitrogen-doped titanium dioxide for air cleaning and disinfecting (2014)

Nitrogen-doped TiO2 nanoparticle photocatalysts were synthesized by a sol–gel procedure using tetra-n-butyl orthotitanate as a titanium precursor and urea as a nitrogen source. Systematic studies for the preparation parameters and their impact on the material's structure were carried out by multiple techniques: thermogravimetric and differential scanning calorimetric analysis, x-ray diffraction, scanning electron microscope, transmission electron microscopy, energy dispersive x-ray spectroscopy and UV–Vis diffuse reflectance spectrophotometry showed that the nitrogen-doped TiO2 calcined at 500 °C for 3 h exhibited a spherical form with a particle size about 15–20 nm and crystal phase presented a mixture of 89.12% anatase. The obtained product was deposited on a porous quartz tube (D = 74 mm; l = 418 mm) to manufacture an air photocatalytic cleaner as a prototype of the TIOKRAFT company's equipment. The created air cleaner was able to remove 60% of 10 ppm acetone within 390 min and degrade 98.5% of bacteria (total aerobic bacteria and fungi, 300 cfu m−3) within 120 min in a 10 m3 box. These photodegradation activities of N-TiO2 are higher than that of the commercial nano-TiO2 (Skyspring Inc., USA, particle size of 5–10 nm).
NYR1972001 Extent of Pollution and Available Treatment for Hydrostatic Test Water (1972)

Describes the pollution aspects of hydrostatic test water. The water used for this testing is obtained from the most convenient local raw surface source. The report describes the results of a three-phase investigation: (l) the study of existing and probable state laws pertaining to this type of pollution, (2) possible violation of state laws by the level of existing hydrostatic test water pollution, and (3) existing methods for treatment of this type of industrial waste.
Decision feedback sequence estimation for unwhitened ISI channels with applications to multiuser detection (1998)

Decision feedback sequence estimation (DFSE), which is a reduced-complexity alternative to maximum likelihood sequence estimation (MLSE), can be used effectively for equalization of intersymbol interference (ISI) as well as for multiuser detection. The algorithm performs very well for whitened (minimum-phase) channels. For nonminimum-phase channels, however, the algorithm is not very effective. Moreover, DFSE requires a noise-whitening filter, which may not be feasible to compute for time-varying channels such as a multiuser direct-sequence code division multiple access (DS-CDMA) channel. Noise-whitening is also cumbersome for applications that involve bidirectional equalization such as the global system for mobile communication (GSM) system. In such conditions, it is desirable to use the Ungerboeck (1974) formulation for sequence estimation, which operates directly on the discrete-time unwhitened statistic obtained from conventional matched filtering. Unfortunately, DFSE based on matched filter statistics is severely limited by untreated interference components. We identify the anticausal interference components, using an error probability analysis. This leads us to a modified unwhitened decision feedback sequence estimator (MUDFSE) in which the components are canceled, using tentative decisions. We obtain approximate error probability bounds for the proposed algorithm. Performance results indicate that the modified algorithm, used on unwhitened channels with relatively small channel correlations, provides similar performance/complexity tradeoffs as the DFSE used on the corresponding whitened minimum-phase channels. The algorithm is especially attractive for multiuser detection for asynchronous DS-CDMA channels with long spreading codes, where it can achieve near-MLSE performance with exponentially lower complexity.
Rationale for Radiation Protection (1974)

Suggestions are made for a more quantitative rationale for radiation protection. Thus, an approach is discussed in which external fields, or the response of suitable detectors exposed to the fields, are transformed into the time-dependent probabilities for specific biological effects in a given species. It is pointed out that detector and computer technologies are emerging which make such a system possible. We offer suggestions for biological experiments which will maximize the usefulness of radiation effects data both in implementing the subject rationale and in the understanding of biological effects.
Desertification in southern Africa (2003)

Proteins constituting the presynaptic machinery of vesicle release undergo substantial conformational changes during the process of exocytosis. While changes in the conformation make proteins vulnerable to aggregation and degradation, little is known about synaptic chaperones which counteract these processes. We show that the cell adhesion molecule CHL1 directly interacts with and regulates the activity of the synaptic chaperones Hsc70, CSP and alphaSGT. CHL1, Hsc70, CSP and alphaSGT form predominantly CHL1/Hsc70/alphaSGT and CHL1/CSP complexes in synapses. Among the various complexes formed by CHL1, Hsc70, CSP and alphaSGT, SNAP25 and VAMP2 induce chaperone activity only in CHL1/Hsc70/alphaSGT and CHL1/CSP complexes, respectively, indicating a remarkable selectivity of a presynaptic chaperone activity for proteins of the exocytotic machinery. In mice with genetic ablation of CHL1, chaperone activity in synapses is reduced and the machinery for synaptic vesicle exocytosis and, in particular, the SNARE complex is unable to sustain prolonged synaptic activity. Thus, we reveal a novel role for a cell adhesion molecule in selective activation of the presynaptic chaperone machinery.
A practical person authentication system using second minor finger knuckles for door security (2017)

Abstract This paper proposes a person authentication system using second minor finger knuckles, i.e., metacarpophalangeal (MCP) joints, for door security. This system acquires finger knuckle patterns on MCP joints when a user takes hold of a door handle and recognizes a person using MCP joint patterns. The proposed system can be constructed by attaching a camera onto a door handle to capture MCP joints. Region of interest (ROI) images around each MCP joint can be extracted from only one still image, since all the MCP joints are located on the front face of the camera. Phase-based correspondence matching is used to calculate matching scores between ROIs to take into consideration deformation of ROIs caused by hand pose changes. Through a set of experiments, we demonstrate that the proposed system exhibits the efficient performance of MCP recognition and also show the potential possibilities of second minor finger knuckles for biometric recognition.
The Effect of Marra Mamba Ore Addition on the Granulation Characteristics of Pisolite Based and Hematite Based Sinter Blends (2005)

The granulation characteristics of two quite different sinter blends have been studied. One comprises a significant proportion of pisolite ore, and the other is dominated by hematite ores. The effect on granulation of adding a significant proportion of West Angelas, a Marra Mamba type ore, into both blends is also studied. The relationship between blend moisture content and green permeability is measured, as is the size distribution of the granulated blends at different moisture contents. It is clear that when West Angelas ore displaces a denser, less porous ore type in a sinter blend, additional granulation moisture must be added to ensure optimal granulation performance. A petrographic study of granule morphology at different blend moisture contents is reported, with particular reference to the features of the adhering layer. The important role of ultrafines, particularly the -50 μm ‘superfine’ fraction, in the granulation process is discussed. The variations in mineralogical and textural characteristics of West Angelas ore with size are presented. It is proposed that the mineralogical and textural characteristics of the superfine particles are an important factor in the granulation performance of an ore or a blend of ores.
The clinical spectrum of type IV collagen mutations (1997)

Clinical manifestations of type IV collagen mutations can vary from the severe, clinically and genetically heterogeneous renal disorder, Alport syndrome, to autosomal dominant familial benign hematuria. The predominant form of Alport syndrome is X-linked; more than 160 different mutations have yet been identified in the type IV collagen alpha 5 chain (COL4A5) gene, located at Xq22-24 head to head to the COL4A6 gene. The autosomal recessive form of Alport syndrome is caused by mutations in the COL4A3 and COL4A4 genes, located at 2q35-37. Recently, the first mutation in the COL4A4 gene was identified in familial benign hematuria. This paper presents an overview of type IV collagen mutations, including eight novel COL4A5 mutations from our own group in patients with Alport syndrome. The spectrum of mutations is broad and provides insight into the clinical heterogeneity of Alport syndrome with respect to age at renal failure and accompanying features such as deafness, leiomyomatosis, and anti-GBM nephritis.
Surface Patterned Porous Films by Convection-Assisted Dynamic Self-Assembly of Zeolite Nanoparticles (2001)

This study demonstrates for the first time that porous zeolite films with surface patterns such as knotted-rope web and wrinkled honeycomb can be obtained by convection-assisted dynamic self-assembly of zeolite nanoparticles. The study also shows that an appropriate dispersant and the presence of zeolite nanoparticles with a specific range of particle sizes in the colloidal suspension are critical for pattern formation. The patterned zeolite films have a well-defined bimodal pore size distribution (i.e., 0.55 and 2.6 nm) with a high Brunauer-Emmett-Teller surface area of 680-750 m(2)/g and are attractive for potential applications in fields such as thin film catalysis, adsorption separation, chemical sensor arrays, and components in microelectronic devices.
The ESTMJS (European Society of Temporomandibular Joint Surgeons) Consensus and Evidence-Based Recommendations on Management of Condylar Dislocation (2021)

Although condylar dislocation is not uncommon, terminology, diagnostics, and treatment concepts vary considerably worldwide. This study aims to present a consensus recommendation based on systematically reviewed literature and approved by the European Society of TMJ Surgeons (ESTMJS). Based on the template of the evidence-based German guideline (register # 007-063) the ESTMJS members voted on 30 draft recommendations regarding terminology, diagnostics, and treatment initially via a blinded modified Delphi procedure. After unblinding, a discussion and voting followed, using a structured consensus process in 2019. An independent moderator documented and evaluated voting results and alterations from the original draft. Although the results of the preliminary voting were very heterogenous and differed significantly from the German S3 guideline (<i>p</i> < 0.0005), a strong consensus was achieved in the final voting on terminology, diagnostics, and treatment. In this voting, multiple alterations, including adding and discarding recommendations, led to 24 final recommendations on assessment and management of TMJ dislocation. To our knowledge, the ESTMJS condylar dislocation recommendations are the first both evidence and consensus-based international recommendations in the field of TMJ surgery. We recommend they form the basis for clinical practice guidelines for the management of dislocations of the mandibular condyle.
HVPE-GaN growth on ammonothermal GaN crystals (2013)

HVPE crystallization on ammonothermaly grown GaN crystals (A-GaN) is described. Preparation of the (0001) surface of the A-GaN crystals to the epi-ready state is presented. The HVPE initial growth conditions are determined and demonstrated. An influence of a thickness and a free carrier concentration in the initial substrate on quality and mode of growth by the HVPE is examined. Smooth GaN layers of excellent crystalline quality, without cracks, and with low dislocation density are obtained.