gebhart/patrepeval huggingface dataset:
Decoding the Chemical Language of Motile Bacteria by Using High‐Throughput Microfluidic Assays (2015)

Motile bacteria navigate chemical environments by using chemoreceptors. The output of these protein sensors is linked to motility machinery and enables bacteria to follow chemical gradients. Understanding the chemical specificity of different families of chemoreceptors is essential for predicting and controlling bacterial behavior in ecological niches, including symbiotic and pathogenic interactions with plants and mammals. The identification of chemical(s) recognized by specific families of receptors is limited by the low throughput and complexity of chemotaxis assays. To address this challenge, we developed a microfluidic-based chemotaxis assay that is quantitative, simple, and enables high-throughput measurements of bacterial response to different chemicals. Using the model bacterium Escherichia coli, we demonstrated a strategy for identifying molecules that activate chemoreceptors from a diverse compound library and for determining how global behavioral strategies are tuned to chemical environments.
2D/3D Face Recognition Using Neural Networks Based on Hybrid Taguchi-Particle Swarm Optimization (2008)

We present a method of face recognition using facial texture and surface information. We first use Gabor wavelets extracting local features at different scales and orientations by gray facial images, then combine the texture with the surface feature vectors based on principal component analysis (PCA) to obtain feature vectors from gray and facial surface images. We propose a hybrid Taguchi particle swarm optimization (HTPSO) algorithm for face recognition based on multilayer neural networks as an identification model. Experimental results demonstrate the efficiency of our method for different face poses and facial expressions. In addition, our work compared with other proposed approaches such as back-propagation (BP), particle swarm optimization (PSO) and the genetic algorithm (GA). With different data modality the experimental results demonstrated that the proposed HTPSO learning algorithm is better than the other approaches in recognition rates. The texture and shape features can improve the efficiency of face recognition.
Avaliação do vínculo mãe-filho e saúde mental de mães de crianças com deficiência intelectual (2013)

The occurrence of weak bond is associated with the Self-Report Questionnaire and socio-cultural conditions. That is, mothers with alteration in the Self-Report Questionnaire are more likely to develop mental disorders, weak bond with their children, the same occurring with the mothers in the most privileged social conditions.
Control of Apple Maggot Flies (Diptera: Tephritidae) with Pesticide-Treated Red Spheres (1995)

Journal Article Control of Apple Maggot Flies (Diptera: Tephritidae) with Pesticide-Treated Red Spheres Get access Jian J. Duan, Jian J. Duan 1 Department of Entomology, University of Massachusetts, Amherst, MA 01003 1Current address: University of Hawaii, Department of Entomology, Kauai Research Station, 7370 Kuamoo Road, Kapaa, HI 96746. Search for other works by this author on: Oxford Academic PubMed Google Scholar Ronald J. Prokopy Ronald J. Prokopy Department of Entomology, University of Massachusetts, Amherst, MA 01003 Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Economic Entomology, Volume 88, Issue 3, 1 June 1995, Pages 700–707, https://doi.org/10.1093/jee/88.3.700 Published: 01 June 1995 Article history Received: 04 January 1993 Accepted: 29 November 1994 Published: 01 June 1995
Embodied Interactions with a Sufi Dhikr Ritual: Negotiating Privacy and Transmission of Intangible Cultural Heritage in “Virtual Sama” (2017)

“Virtual Sama” is an interactive multimedia installation that connects computationally abstracted ethnographic documentation of a Sufi Dhikr ritual with viewers through an artistic artificial intelligence (AI) abstraction process and interactive rhythmic full body movement. In this paper, we describe how the installation is designed to elicit reflection on the implications of transforming intangible heritage into digital heritage through digital documentation and storage, and to encourage exploration of questions around privacy and safeguarding of sensitive cultural practices. Against the context of detailed fieldwork with Uyghur Sufi practitioners in Xinjiang, China, we explore how AI processes and embodied interaction might be mobilised to present alternative representations of anonymity, while drawing attention to the complexities of representation, access and transmission of intangible cultural practices in the digital age.
Pharmacodynamics of warfarin in cats (2000)

The overall purpose of this study was to evaluate the pharmacodynamic response to warfarin in cats. The specific aim was to determine if a log‐linear indirect response model ( Nagashima et al ., 1969 ) used to describe the in vivo effect of warfarin in humans could be applied to cats. The pharmacokinetics of racemic warfarin were described using a non‐compartmental approach. The relationship between prothrombin complex activity (PCA) and normalized prothrombin time (PTR) was defined for feline plasma under our experimental conditions, and determined to be: %PCA=12.38+648 e − PTR/0.492. These data were then integrated and used to predict the warfarin dose associated with therapeutic anti‐coagulation defined as an International Normalized Ratio (INR) of 2.0–3.0. The maximum prothrombinopenic response to warfarin in cats after a single intravenous dose of 0.5 mg/kg occurred at 24–48 h. Pharmacodynamic modeling suggested that each cat had a narrow therapeutic range of the steady‐state concentration of total warfarin required to appropriately block prothrombin complex synthesis (median: 265.2–358.7 ng/mL). The median daily dose range predicted to yield therapeutic concentrations of warfarin was 0.061–0.088 mg/kg per day. Wide inter‐individual variations in both pharmacokinetics and pharmacodynamic response suggest that a more optimal dosing of warfarin may be possible with the development of individual pharmacokinetic/pharmacodynamic algorithms, analogous to those currently employed in human patients.
pH‐Responsive Switching of the Near‐Infrared Absorption of the Water‐Soluble Bis(o‐diiminobenzosemiquinonato)platinum(II) Complex (2010)

Abstract The electronic structure of a water‐soluble near‐infrared (NIR)‐absorbing complex was determined to be singlet diradical [Pt II (L ISQ ) 2 ] 2– [(L ISQ ) 2– · = o ‐diiminosulfobenzosemiquinonate radical] by X‐ray diffraction and 1 H NMR spectroscopy. Cyclic voltammetry (CV) showed redox reactions of [Pt II (L ISQ ) 2 ] 2– to give [Pt II (L ISQ )(L IBQ )] – ( E ${1 \over 2}$ 1 = –0.26 V vs. Fc + /Fc) and [Pt II (L ISQ )(L PDI )] 3– ( E ${1 \over 2}$ 2 = –1.46 V) [(L IBQ ) – = o ‐diiminosulfobenzoquinonate, (L PDI ) 3– = o ‐phenylenediiminesulfonate]. The monoradical structure of the latter was confirmed by electron paramagnetic resonance (EPR) spectroscopy. Splitting of the reduction wave of [Pt II (L ISQ )(L IBQ )] – in CV and the weak EPR signal suggested the formation of a dimer. Because the rest potential of the solution exceeds E pa 1 at pH 4.0, the decrease in the NIR absorption at pH &lt; 4.0 can be attributed to the oxidation of [Pt II (L ISQ ) 2 ] 2– followed by dimerization.
Decreased NPC1L1 expression in the liver from Chinese female gallstone patients (2010)

The decreased hepatic NPC1L1 levels in female GS might indicate a downregulated reabsorption of biliary cholesterol in the liver, which, in turn, leads to the cholesterol supersaturation of bile. Our data are consistent with the possibility that hepatic NPC1L1 may be mediated by SREBP2.
Surpassing limits of static RNA modification analysis with dynamic NAIL-MS (2018)

Ribonucleic acids (RNA) are extensively modified. These modifications are quantified by mass spectrometry (LC-MS/MS) to determine the abundance of a modification under certain conditions or in various genetic backgrounds. With LC-MS/MS the steady state of modifications is determined, and thus we only have a static view of the dynamics of RNA modifications. With nucleic acid isotope labeling coupled mass spectrometry (NAIL-MS) we overcome this limitation and get access to the dynamics of RNA modifications. We describe labeling techniques for E. coli, S. cerevisiae and human cell culture and the current instrumental limitations. We present the power of NAIL-MS but we also outline validation experiments, which are necessary for correct data interpretation. As an example, we apply NAIL-MS to study the demethylation of adenine and cytidine, which are methylated by the damaging agent methyl-methanesulfonate in E. coli. With NAIL-MS we exclude the concurrent processes for removal of RNA methylation, namely RNA degradation, turnover and dilution. We use our tool to study the speed and efficiency of 1-methyladenosine and 3-methylcytidine demethylation. We further outline current limitations of NAIL-MS but also potential future uses for e.g. relative quantification of tRNA isoacceptor abundances.
Operating-Room Throughput: Strategies for Improvement (2009)

Saleh, Khaled J. MD; Novicoff, Wendy M. PhD; Rion, David MD; MacCracken, Linda H. MBA; Siegrist, Richard MS, MBA Author Information
Aqueous Dispersion and Slip Casting of Boron Carbide Powder: Effect of pH and Oxygen Content (1991)

The effect of pH and oxygen content on the zeta potential, viscosity, and casting performance of fine (&gt;3 μm) boron carbide powder is presented. X‐ray photoelectron spectroscopy of the powder revealed a surface layer of adsorbed water and oxides of boron and carbon. The soluble boric acid impurity was removed by washing the powder with water or alcohols. Electrophoresis indicated that the B 4 C surface was negatively charged in water above pH 1, but the presence of dissolved boric acid suppressed the zeta potential at high pH. Stable, low‐viscosity dispersions of &gt;30 vol% solids were prepared and slip cast at pH &gt;6, but boric acid was destabilizing for dispersions prepared above pH 7. The green density of slip‐cast parts was more reproducible and about 3% to 5% higher for washed powders than for high‐oxygen‐content powders.
Comparative analysis for renal stereotactic body radiotherapy using Cyberknife, VMAT and proton therapy based treatment planning (2018)

This dosimetric study supports the feasibility of a multi-center trial for renal SBRT using PBS, VMAT and Cyberknife.
Mechanism for Singlet Fission in Pentacene and Tetracene: From Single Exciton to Two Triplets (2011)

Singlet fission (SF) could dramatically increase the efficiency of organic solar cells by producing two triplet excitons from each absorbed photon. While this process has been known for decades, most descriptions have assumed the necessity of a charge-transfer intermediate. This ab initio study characterizes the low-lying excited states in acene molecular crystals in order to describe how SF occurs in a realistic crystal environment. Intermolecular interactions are shown to localize the initially delocalized bright state onto a pair of monomers. From this localized state, nonadiabatic coupling mediated by intermolecular motion between the optically allowed exciton and a dark multi-exciton state facilitates SF without the need for a nearby low-lying charge-transfer intermediate. An estimate of the crossing rate shows that this direct quantum mechanical process occurs in well under 1 ps in pentacene. In tetracene, the dark multi-exciton state is uphill from the lowest singlet excited state, resulting in a dynamic interplay between SF and triplet-triplet annihilation.
Self‐titration of insulin in the management of people with type 2 diabetes: a practical solution to improve management in primary care (2012)

Good glycaemic control in type 2 diabetes (T2DM) is associated with a reduced risk of diabetes complications; however, achieving and maintaining glycaemic control represents a major challenge to physicians, and despite the availability of a range of antidiabetic therapies, many patients with T2DM will eventually require insulin supplementation to reach target glycaemic levels. Insulin initiation, adjustment of the insulin dose and the need for frequent assessment of blood glucose levels are often complicated by patient and physician misconceptions and concerns regarding its use. For most patients requiring insulin therapy, dose titration is carried out by physicians; however, evidence suggests that this process may not provide optimal glycaemic management for patients. Self-monitoring of blood glucose and self-adjustment of insulin dose (insulin self-titration) is well established in type 1 diabetes, suggesting that similar therapeutic self-management may be beneficial when applied to patients with T2DM. This article reviews the rationale and clinical evidence for insulin self-titration in patients with T2DM with the aim of highlighting the importance of educating patients about insulin therapy and empowering them to manage their diabetes through self-titration of insulin.
Les matières grasses laitières comme précurseurs d'arômes dans les fromages. Focus sur les estérases lipolytiques et libération d'acides gras précurseurs d'arômes (2014)

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Peptide YY inhibits vasopressin-stimulated chloride secretion in inner medullary collecting duct cells (1998)

mIMCD-k2 cells are derived from the inner medullary collecting duct of a mouse and exhibit electrogenic sodium absorption and cAMP- and vasopressin (AVP)-stimulated electrogenic chloride secretion [N. L. Kizer, B. Lewis, and B. A. Stanton. Am. J. Physiol. 268 (Renal Fluid Electrolyte Physiol. 37): F347-F355, 1995; and N. L. Kizer, D. Vandorpe, B. Lewis, B. Bunting, J. Russell, and B. A. Stanton. Am. J. Physiol. 268 (Renal Fluid Electrolyte Physiol. 37): F854-F861, 1995]. The purpose of the present study was to determine how peptide YY (PYY) affects electrogenic Na+ and Cl- current in mIMCD-k2 cells. Short-circuit currents (Isc) were measured across monolayers of mIMCD-k2 cells mounted in Ussing-type chambers. PYY did not alter baseline Isc, nor did it alter Isc in chloride-free conditions, indicating no effect on electrogenic sodium transport. Baseline chloride current in these cells is low; therefore, chloride short-circuit current (IClsc) was stimulated with AVP (10 nM) added to the basolateral surface and 10 microM amiloride added to the apical surface. Although apical applications of PYY had no effect, basolateral application of PYY caused attenuation of IClsc, with the maximal inhibitory dose (100 nM) causing 52 +/- 1.3% inhibition (IC50 = 0.11 nM). Inhibition by PYY of IClsc is mediated through the Y2 receptor subtype, as PYY-(3-36) was the only PYY analog tested that caused inhibition and was equipotent to PYY. Inhibition by PYY of IClsc was abolished following incubation with pertussis toxin. We also show that PYY inhibits AVP-stimulated cAMP accumulation, with a maximal inhibitory dose (100 nM) causing a 38% +/- 6% inhibition (IC50 = 0.16 nM), comparable to inhibition by PYY of IClsc. We conclude that PYY acts through either Gi or Go to inhibit adenylate cyclase activity, leading to a decrease in AVP-stimulated chloride current.
Organogels from lecithins (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOrganogels from lecithinsRoger Scartazzini and Pier Luigi LuisiCite this: J. Phys. Chem. 1988, 92, 3, 829–833Publication Date (Print):February 1, 1988Publication History Published online1 May 2002Published inissue 1 February 1988https://pubs.acs.org/doi/10.1021/j100314a047https://doi.org/10.1021/j100314a047research-articleACS PublicationsRequest reuse permissionsArticle Views1249Altmetric-Citations283LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Tiny Olfactory Display Using Surface Acoustic Wave Device and Micropumps for Wearable Applications (2016)

Olfaction is expected to provide reality and immersive feeling in multimedia contents. Thus, an olfactory display, a gadget to present scents to one or more user(s), has been developed for a past decade. A wearable olfactory display has advantage from the viewpoint of reducing the odorant diffusion into the atmosphere and is appropriate for virtual reality applications. In this paper, we developed a portable olfactory display using a surface acoustic wave (SAW) device and micropumps. To realize a miniaturized olfactory display, we implemented a signal generator into field programmable gate array and we designed the dedicated unit combining micropump with odorant reservoir. To evaluate the olfactory display, we used a quartz crystal microbalance (QCM) gas sensor. In the experiment, we found the proper angle of the olfactory display and the maximum distance at which the user can certainly sniff scents. In addition, we confirmed that the olfactory display can present intended concentration of the odorant. Furthermore, it was found that the olfactory display can atomize even a low-volatile odor compound with the micropump providing insignificant amount of odors to the SAW device.
Nitric Oxide Synthase Gene Therapy Rapidly Reduces Adhesion Molecule Expression and Inflammatory Cell Infiltration in Carotid Arteries of Cholesterol-Fed Rabbits (1999)

NO synthase gene therapy rapidly ameliorates several markers of atherosclerosis in the cholesterol-fed rabbit.
Anaplastic lymphoma kinase as a therapeutic target (2012)

Several ALK inhibitors have recently been developed, offering new treatment options in tumors driven by abnormal ALK signaling. However, as observed with other tyrosine kinase inhibitors, resistance has emerged in patients treated with these agents. The complexity of mechanisms of acquired resistance recently described suggests that other therapeutic options, including combination of ALK and other kinases targeted drugs, will be required in the future.
Adverse events of herbal food supplements for body weight reduction: systematic review* (2005)

Herbal weight-loss supplements are marketed with claims of effectiveness. Our earlier systematic review identified data from double-blind, randomized controlled trials for a number of herbal supplements. The aim of this systematic review was to assess all clinical evidence of adverse events of herbal food supplements for body weight reduction for which effectiveness data from rigorous clinical trials exist. We assessed Ephedra sinica, Garcinia cambogia, Paullinia cupana, guar gum, Plantago psyllium, Ilex paraguariensis and Pausinystalia yohimbe. Literature searches were conducted on Medline, Embase, Amed and The Cochrane Library. Data were also requested from the spontaneous reporting scheme of the World Health Organization. We hand-searched relevant medical journals and our own files. There were no restrictions regarding the language of publication. The results show that adverse events including hepatic injury and death have been reported with the use of some herbal food supplements. For herbal ephedra and ephedrine-containing food supplements an increased risk of psychiatric, autonomic or gastrointestinal adverse events and heart palpitations has been reported. In conclusion, adverse events are reported for a number of herbal food supplements, which are used for reducing body weight. Although the quality of the data does not justify definitive attribution of causality in most cases, the reported risks are sufficient to shift the risk-benefit balance against the use of most of the reviewed herbal weight-loss supplements. Exceptions are Garcinia cambogia and yerba mate, which merit further investigation.
Advanced UNIX Programming (1985)

From the Publisher:
The value of this book lies in its ability to draw out the UNIX system's magnificent blend of simplicity and power - the strengths, weaknesses, and underlying rationale contained in each UNIX design feature. Shows how, when, and why system calls are used in important UNIX versions to interface user subroutines and commands with Kernel facilities. Now systems programmers, software engineers, and C/UNIX users can cover UNIX system calls easily and portable with this complete, detailed, how-to reference.
Evenwichtsonderzoek bij TNO TM (TNO Technische Menskunde) [Equilibrium research at TNO-HFRI (TNO Human Factors Research Institute Soesterberg)] (1995)

Het hoofdstuk geeft een overzicht van de ontwikkelingen van het evenwichtsonderzoek bij TNO TM. Het spitst zich toe op het onderzoek naar het functioneren van de otolieten zowel in het achtergrondsonderzoek als het toegepaste onderzoek, en op de betekenis daarvan voor lucht- en zeevarenden.
Organotin derivatives of maleic acid (1967)

The synthesis of a number of trialkyl- and triaryl-tin maleates, methyl maleates, and fumarates is described. The preparation of dibutylchlorotin methyl maleate and dibutyltin bis(methyl maleate) and reaction of these compounds with 2,2′-bipyridyl are discussed. Treatment of dibutyltin oxide with maleic acid gives a mixture from which three forms of dibutyltin maleate have been isolated. The structures of all these compounds are discussed with reference to their infrared spectra.
CDuce: An XML-Centric General-Purpose Language (2003)

Abstract. We present the functional language CDuce, discuss some design issues, and show its adequacy for working with XML documents. Distinctive features of CDuce are a powerful pattern matching, first class functions, overloaded functions, a very rich type system (arrows, sequences, pairs, records, intersections, unions, differences), precise type inference for patterns and error localization, and a natural interpretation of types as sets of values. We also outline some important implementation issues; in particular, a dispatch algorithm that demonstrates how static type information can be used to obtain very efficient compilation schemas.