gebhart/patrepeval huggingface dataset:
Deep Convolutional Neural Networks for Breast Cancer Histology Image Analysis (2018)

Abstract Breast cancer is one of the main causes of cancer death worldwide. Early diagnostics significantly increases the chances of correct treatment and survival, but this process is tedious and often leads to a disagreement between pathologists. Computer-aided diagnosis systems showed potential for improving the diagnostic accuracy. In this work, we develop the computational approach based on deep convolution neural networks for breast cancer histology image classification. Hematoxylin and eosin stained breast histology microscopy image dataset is provided as a part of the ICIAR 2018 Grand Challenge on Breast Cancer Histology Images. Our approach utilizes several deep neural network architectures and gradient boosted trees classifier. For 4-class classification task, we report 87.2% accuracy. For 2-class classification task to detect carcinomas we report 93.8% accuracy, AUC 97.3%, and sensitivity/specificity 96.5/88.0% at the high-sensitivity operating point. To our knowledge, this approach outperforms other common methods in automated histopathological image classification. The source code for our approach is made publicly available at https://github.com/alexander-rakhlin/ICIAR2018
Small-signal analysis of a square helix TWT (2016)

The small signal gain of the square helix TWT has been calculated based on the improved tape model. It is clearly shown that the square helix TWT possesses higher peak gain than that of the equivalent round helix TWT, which indicates higher output power under the identical device length.
Revolta da antena: redes, dispositivos móveis, artivismo e mídia livre nas manifestações de 2013 no Brasil (2014)

Este artigo visa discutir as influencias exercidas pelas tecnologias de redes digitais, facilidades tecnológicas e dispositivos móveis nos eventos de manifestações populares e artivismo que vem acontecendo no mundo globalizado. O foco principal direciona-se às jornadas de junho de 2013 no Brasil, fazendo um levantamento de como ações de artivismo podem representar alternativas de ação na ocupação do espaço público, como a mídia livre pode representar uma alternativa distinta da mídia tradicional comercial na divulgação das informações e revelando a importância de projetos como a Revolta da Antena, desenvolvido em Florianópolis, nesse contexto. Ao refletir sobre as propostas da Revolta da Antena, centralizada sobre a ideia da liberdade de informação, analisa-se as possibilidades e influencias da sociedade de redes com relação ao ser humano e as novas mídias, nos contextos sociais contemporâneos, pontuando novas possibilidades de interação midiática e social.
HCV genotype 1a shows a better virological response to antiviral therapy than HCV genotype 1b (2012)

ClinicalTrials.gov Identifier: NCT01342003.
Performance of pilot carrier based Doppler compensation for CDMA land mobile satellite links (2002)

The performance of a Doppler estimation scheme for CDMA land mobile LEO satellite systems under realistic channel conditions is studied by computer simulation. The scheme can be applied in Doppler compensation of the received signals, to aid in the code acquisition under the severe Doppler conditions offered by the satellite channel. The proposed scheme is based on a continuous-wave pilot carrier placed at the first spectral null of the CDMA user signal. The results show that Doppler estimation and compensation is possible with very high reliability, giving a probability of correct estimate >0.9995 down to 25/spl deg/ elevation with /spl plusmn/250 Hz accuracy. However, in the urban shadowed channel state the performance is poor and reliable Doppler estimation is not possible. The estimator is also able to track the variation of Doppler with time even under the worst-case Doppler rate conditions. The estimator structure is simple, requiring only an FFT with averaging as post processing. By assuming that the proposed Doppler compensation was achieved to /spl plusmn/250 Hz accuracy, code acquisition was demonstrated to be feasible with acceptable acquisition time by a 1-dimensional serial search instead of the considerably longer 2-dimensional search that would be required in the uncompensated case.
The Complementary FET (CFET) for CMOS scaling beyond N3 (2018)

The complementary FET (CFET) device consisting of a stacked n-type vertical sheet on a p-type fin is evaluated in a design-technology co-optimization (DTCO) framework. Through a double level access it offers a structural scaling of both standard cells (SDC) and SRAM by 50%. The proposed process flow requires accurate control of the elevation dimension for manufacturability. Based on TCAD analysis, the CFET can eventually outperform the finFET device and meet the N3 targets in power and performance. To achieve that, the dominating parasitic resistance of the deep vias needs to be reduced by the introduction of advanced MOL contacts featuring thin barriers.
Addition of clonidine and fentanyl: comparison between three different regional anesthetic techniques in circumcision (2005)

Dorsal penile block plus RB technique is superior to dorsal penile block alone and RB alone in reducing postcircumcision pain in children.
Unambiguous Techniques Modernized GNSS Signals: Surveying the solutions (2017)

Global navigation satellite systems (GNSSs) remain, by far, the most reliable and widely spread sources of accurate outdoor positioning. With the advent of the new and modernized signals, novel challenges related to GNSS receivers have also been recognized. One of the most important challenges in dealing with modernized GNSS signals is posed by the oscillatory behavior of the autocorrelation of some of those signals, which causes ambiguities in the measurement of the propagation delay. This article is an extensive survey of the solutions in this area proposed during past decades. Not only does it illustrate that a large pool of solutions is available, but it also shows that none of these solutions alone can currently overcome all of the challenges related to GNSS ambiguities. A thorough overview of the problems caused by the ambiguities in the delay estimation and the unambiguous techniques proposed to counteract them is presented. We hope to spark the interest of the signal processing community and to stimulate new advances in this field. Unambiguous methods are classified into three main classes, and we compare the main solutions in terms of complexity and performance to identify the most promising techniques and directions to be followed. We point out that there is an inherent tradeoff between the unambiguous acquisition and unambiguous tracking, and that the receiver stages of acquisition and tracking can be designed in a disjoint manner when dealing with the ambiguities.
Inclusion of a single-tail amino acid-based amphiphile in a lipoplex formulation: Effects on transfection efficiency and physicochemical properties (2011)

Effects of the addition of a cationic amino acid-based synthetic amphiphile, arginine N-lauroyl amide dihydrochloride (ALA), to a lipid-based transfection formulation have been investigated. It is shown that the inclusion of ALA results in a substantial enhancement of the transfection capability of lipoplexes prepared with liposomes of 1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine and cholesterol, which themselves mediate highly efficient transfection. A possible explanation for the increased biological activity is that ALA adsorbed to the surface of the DNA-lipid complexes is involved in triggering internalization. However, in order to identify possible additional factors underlying the enhanced transfection efficiency, the physical properties of formulations with and without ALA were characterized using cryo-transmission electron microscopy, dynamic light scattering, and an ethidium bromide intercalation assay. ALA seems to have limited influence on the initial internal structure of the complexes and the protection of DNA, but its presence is found to decrease the average effective size of the dispersed particles; this change in size may be important in improving the biological activity. Furthermore, ALA can act to influence the transfection efficiency of the formulation by promoting the release of DNA following internalization in the transfected cells.
Dysferlin overexpression in skeletal muscle produces a progressive myopathy (2009)

Expression levels of dysferlin are important for appropriate function without deleterious or cytotoxic effects. As a corollary, we propose that future endeavors in gene replacement for correction of dysferlinopathy should be tailored to take account of this.
Strained-SOI/SGOI Dual Channel CMOS Technology Based on Ge Condensation Technique (2006)

In this paper, fabrication of the dual channel CMOS devices based on the Ge-condensation technique is demonstrated as well as their mobility and current drive enhancements. Ge-rich strained SGOI pMOSFETs were integrated with strained Si/SGOI nMOSFETs by a CMOS process combined with the Ge condensation process, in which the strain in the SGOI layers were properly controlled. As a result, significant electron- and hole-mobility enhancements for the strained SOI and SGOI channels were observed as well as I <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">d</sub> enhancements
Is last-mile delivery a 'killer app' for self-driving vehicles? (2018)

research-article Share on Is last-mile delivery a 'killer app' for self-driving vehicles? Authors: Huaxia Xia Meituan MeituanView Profile , Haiming Yang JD CTO Group JD CTO GroupView Profile Authors Info & Claims Communications of the ACMVolume 61Issue 11November 2018 pp 70–75https://doi.org/10.1145/3239552Published:26 October 2018Publication History 8citation5,391DownloadsMetricsTotal Citations8Total Downloads5,391Last 12 Months358Last 6 weeks10 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Albert Le Bonheur, La sculpture indonésienne au Musée Guimet, catalogue et étude iconographique (1971)

Lombard Denys. Albert Le Bonheur, La sculpture indonésienne au Musée Guimet, catalogue et étude iconographique. In: Archipel, volume 2, 1971. pp. 253-254.
An Efficient Convex Formulation for Model-Predictive Control on Wave-Energy Converters (2017)

Model-Predictive Control (MPC) has shown its strong potential in maximizing energy extraction for Wave-Energy Converters (WECs) while handling hard constraints. As MPC can solve the optimization problem on-line, it can better account for state changes and reject disturbances from the harsh sea environment. Interests have arisen in applying MPC to an array of WECs, since researchers found that multiple small-size WECs are more economically viable than a single large-size WEC. However, the computational demand is known to be a primary concern for applying MPC in real-time, which can determine the feasibility of such a controller, particularly when it comes to controlling an array of absorbers. In this paper, we construct a cost function and cast the problem into a Quadratic Programming (QP) with the machinery force being the “optimizer,” for which the convexity can be guaranteed by introducing a penalty term on the slew rate of the machinery force. The optimization problem can then be solved efficiently, and a feasible solution will be assured as the global optima. Constraints on the motion of the WEC and the machinery force will be taken into account. The current MPC will be compared to others existing in literature, including a nonlinear MPC [1] which has been applied in wave-tank tests. The effects of constraints on the control law and the absorbed power are investigated. Performances of the WEC are shown for both regular and irregular wave conditions. The current MPC is found to have good energy-capture capability and is able to broaden the band-width for capturing wave energy. The reactive power required by the PTO system is presented. The additional penalty term provides a tuning parameter, of which the effects on the MPC performance and the reactive power requirement are discussed.
HIGHLY SENSITIVE SYNCHRONOUS SPECTROFLUORIMETRIC METHOD FOR DETERMINATION OF STIRIPENTOL IN CAPSULES AND HUMAN URINE: APPLICATION TO IN-VITRO DRUG RELEASE AND WEIGHT VARIATION TEST (2014)

A highly sensitive and simple spectrofluorimetric method has been developed and validated for the determination of stiripentol (STP) in its pharmaceutical formulations and human urine. The proposed method is based on the investigation of the fluorescence spectral behaviour of STP in methanol using synchronous scan technique (Δλ=80 nm, 343 nm). The fluorescence–concentration plot was rectilinear over the range 10–70 ng/mL, with lower detection limit of 2ng/mL. The proposed method was successfully applied to the assay of commercial capsules, spiked urine samples as well as weight variation testing. The application of the proposed method was extended to test the in-vitro drug release of STP capsules, according to USP guidelines.
Enzymatically crosslinked gelatin hydrogel promotes the proliferation of adipose tissue-derived stromal cells (2016)

Gelatin hydrogel crosslinked by microbial transglutaminase (mTG) exhibits excellent performance in cell adhesion, proliferation, and differentiation. We examined the gelation time and gel strength of gelatin/mTG hydrogels in various proportions to investigate their physical properties and tested their degradation performances <i>in vitro</i>. Cell morphology and viability of adipose tissue-derived stromal cells (ADSCs) cultured on the 2D gel surface or in 3D hydrogel encapsulation were evaluated by immunofluorescence staining. Cell proliferation was tested via Alamar Blue assay. To investigate the hydrogel effect on cell differentiation, the cardiac-specific gene expression levelsof Nkx2.5, Myh6, Gja1, and Mef2c in encapsulated ADSCs with or without cardiac induction medium were detected by real-time RT-PCR. Cell release from the encapsulated status and cell migration in a 3D hydrogel model were assessed <i>in vitro</i>. Results show that the gelatin/mTG hydrogels are not cytotoxic and that their mechanical properties are adjustable. Hydrogel degradation is related to gel concentration and the resident cells. Cell growth morphology and proliferative capability in both 2D and 3D cultures were mainly affected by gel concentration. PCR result shows that hydrogel modulus together with induction medium affects the cardiac differentiation of ADSCs. The cell migration experiment and subcutaneous implantation show that the hydrogels are suitable for cell delivery.
Hydrolysis of α‐Tricalcium Phosphate in Simulated Body Fluid and Dehydration Behavior During the Drying Process (2007)

The hydrolysis of α‐tricalcium phosphate (α‐TCP) in a simulated body fluid (SBF) at 37°C was investigated. The hydration rate was found to be slower in SBF than that in deionized water. The concentration of ions in SBF was monitored by ICP. The hydrolysis product, which was characterized by X‐ray diffraction, scanning electron microscopy, transmission electron microscopy, Fourier transform infra red, and X‐ray photoelectron spectroscopy, was determined to be carbonate‐containing, calcium‐deficient hydroxyapatite (CO 3 −CDHAp) with Mg 2+ , Na + , and Cl − impurities similar to the biological apatite. An amorphous layer on the α‐TCP surface was found to be the precursor of the apatite phase, which may either form crystalline apatite or may decompose back to α‐TCP at a lower temperature.
WKB analysis of bend losses in optical waveguides (2000)

A more complete Wentzel-Kramers-Brillouin (WKB) analysis of bend losses is given for a circularly curved waveguide. Using the WKB approximation with a conformal transformation of a curved optical waveguide, is shown to give more accurate bend loss results.
54. Identification and cellular localisation of cyclooxygenase-1 and -2 in the adult rat testis (2003)

Reproduction, Fertility and Development is an international journal publishing original research , review and comment in the fields of reproduction and developmental biology in humans, domestic animals and wildlife
Development of a Diversity-Based Approach for the Discovery of Stereoselective Polymerization Catalysts: Identification of a Catalyst for the Synthesis of Syndiotactic Polypropylene (2000)

Combinatorial methods have recently been used to aid in the discovery of new pharmaceuticals and catalysts for organic synthesis. A simple and inexpensive strategy for using combinatorial methods to discover polymerization catalysts is reported, and using it enabled a new catalyst (1, see scheme) for the synthesis of syndiotactic polypropylene to be identified.
Visible wavelength silicon nitride focusing grating coupler with AlCu/TiN reflector (2013)

High-performance silicon nitride focusing grating couplers with AlCu/TiN reflectors for a visible wavelength (660 nm) have been designed and fabricated in a standard complementary metal-oxide-semiconductor pilot line. The influence of the bottom oxide cladding thickness on the grating decay length and efficiency is theoretically and experimentally investigated. It is shown how the metal reflector not only increases the efficiency but also allows reduction of the radiated beam size. Coupling efficiencies above 59% have been measured for compact focusing gratings.
Genetic mapping of agronomic traits in false flax (Camelina sativa subsp.sativa) (2006)

The crucifer oilseed plant false flax (Camelina sativa subsp. sativa) possesses numerous valuable agronomic attributes that make it attractive as an alternative spring-sown crop for tight crop rotations. The oil of false flax is particularly rich in polyunsaturated C18-fatty acids, making it a valuable renewable feedstock for the oleochemical industry. Because of the minimal interest in the crop throughout the 20th century, breeding efforts have been limited. In this study, a genetic map for C. sativa was constructed, using amplified fragment length polymorphism (AFLP) markers, in a population of recombinant inbred lines that were developed, through single-seed descent, from a cross between 'Lindo' and 'Licalla', 2 phenotypically distinct parental varieties. Three Brassica simple sequence repeat (SSR) markers were also integrated into the map, and 1 of these shows linkage to oil-content loci in both C. sativa and Brassica napus. Fifty-five other SSR primer combinations showed monomorphic amplification products, indicating partial genome homoeology with the Brassica species. Using data from field trials with different fertilization treatments (0 and 80 kg N/ha) at multiple locations over 3 years, the map was used to localize quantitative trait loci (QTLs) for seed yield, oil content, 1000-seed mass, and plant height. Some yield QTLs were found only with the N0 treatment, and might represent loci contributing to the competitiveness of false flax in low-nutrient soils. The results represent a starting point for future marker-assisted breeding.
Cyclization products of 2-(3-chloro-4-methyl-benzoyl)benzoic acid by polyphosphoric acid. (1984)

The reaction of 2-(3 chloro-4-methylbenzoyl)benzoic acid [1] in polyphosphoric acid at 100-140°C gave 2-chloro-3-[3-chloro-2-methy1-10-oxo-9(10 H)-anthrylidenemethyl]anthraquinone [4] along with 1-chloro-2-methyl- and 2-chloro-3-methylanthraquinones [2] and [3]. Only [2] and [3] were formed at 75°C. The structure of [4] was determined based on its MS; -IR.; 'NMR and UV spectra and its chemical behavior. Mechanism for the formation of [4] is discussed.
Progress on the European Gas Turbine Program “AGATA” (1998)

The four-year European Gas Turbine Program “AGATA” was started in January 1993 with the objective of developing three critical components aimed at a 60 kW turbogenerator in an hybrid electric vehicle: a catalytic combustor, a radial turbine wheel and a static heat exchanger. The AGATA partners represent car manufacturers as well as companies and research institutes in the turbine, catalyst, and ceramic material fields in both France and Sweden. This paper outlines the main results of the AGATA project for the first three-year period. Experimental verification of the components started during the third year of the program. A high-pressure/temperature test rig for the combustor and the heat exchanger tests has been built and is now being commissioned. A high-temperature turbine spin rig will be ready late 1995. The turbine wheel design is completed and ceramic Si3N4 spin disks have been manufactured by injection molding and Hot Isostatic Pressing (HIP). A straight blade design has been selected and FEM calculations have indicated that stress levels that occur during a cold start are below 300 MPa. The catalytic combustor final design for full-scale testing has been defined. Due to the high operating temperature, 1350°C, catalyst pilot tests have included aging, activity, and strength tests. Based on these tests, substrate and active materials have been selected. Initial full-scale tests including LDV measurements in the premix duct will start late 1995. The heat exchanger design has also been defined. This is based on a high-efficiency plate recuperator design. One critical item is the ceramic thermoplastic extrusion manufacturing method for the extremely thin exchanger plates another is the bonding technique: ceramic to ceramic and ceramic to metal. Significant progress on these two items has been achieved. The manufacturing of quarter scale prototypes is now in process.
A pseudo-machine for packet monitoring and statistics (1988)

This paper concerns the design of a flexible and efficient packet monitoring program for analyzing traffic patterns and gathering statistics on a packet network. This monitor operates in real time, using an analyzer which is an interpretive pseudo-machine driving object-oriented data collection programs. The pseudo-program for the interpreter is “compiled” from configuration commands written in a monitoring control language.
The effect of hydroxyapatite addition on the mechanical properties of polyvinyl alcohol/chitosan biomaterials for bone scaffolds application (2018)

The increasing number of bone fracture incident in Indonesia from year to year needs an urgent problem solving of the limited bone substitute which can meet the necessary criteria for that purpose. Motivated by this, therefore, the current study is focusing on the optimization of material properties used as bone scaffold. A biomaterial of polyvinyl alcohol (PVA)/chitosan-hydroxyapatite (HA) composite was successfully made by wet chemistry method, followed by freeze thawing and freeze drying. For comparison purposes, the percentage of HA has been varied from 0, 25 and 40 % (wt/v). The resulting composites were characterized by Fourier transform infrared (FTIR) spectroscopy, scanning electron microscope (SEM), compressive test, and swelling behavior. The results showed that the addition of HA up to 40% (wt/v) has yielded a porous structure with an average pore size of 42.39 µm. In addition, the compressive modulus was enhanced from 14 MPa for 0% HA to 143, and 191 MPa for composites with the addition of HA from 25 to 40% (wt/v). The addition of HA has also reduced the swelling ratio from 296% for the sample without HA to 85 and 78 % for sample with addition of HA from 25 to 40 (wt/v), respectively. The obtained results show that PVA/chitosan-HA in this study is potential to be used as scaffold in bone tissue engineering.