gebhart/patrepeval huggingface dataset:
Fecal Incontinence and the Risk of Urinary Tract Infection in Patients Presenting for Urogynecological Consultation (2023)

The prevalence of UTI and recurrent UTI was similar in urogynecology patients with and without FI. Variables that were associated with UTI risk included older age, sexual activity, diabetes mellitus, and anterior vaginal wall prolapse.
Role of Envelope Glycoprotein Complexes in Cell-Associated Spread of Human Cytomegalovirus (2021)

The role of viral envelope glycoproteins, particularly the accessory proteins of trimeric and pentameric gH/gL-complexes, in cell-associated spread of human cytomegalovirus (HCMV) is unclear. We aimed to investigate their contribution in the context of HCMV variants that grow in a strictly cell-associated manner. In the genome of Merlin pAL1502, the glycoproteins gB, gH, gL, gM, and gN were deleted by introducing stop codons, and the mutants were analyzed for viral growth. Merlin and recent HCMV isolates were compared by quantitative immunoblotting for expression of accessory proteins of the trimeric and pentameric gH/gL-complexes, gO and pUL128. Isolates were treated with siRNAs against gO and pUL128 and analyzed regarding focal growth and release of infectious virus. All five tested glycoproteins were essential for growth of Merlin pAL1502. Compared with this model virus, higher gO levels were measured in recent isolates of HCMV, and its knockdown decreased viral growth. Knockdown of pUL128 abrogated the strict cell-association and led to release of infectivity, which allowed cell-free transfer to epithelial cells where the virus grew again strictly cell-associated. We conclude that both trimer and pentamer contribute to cell-associated spread of recent clinical HCMV isolates and downregulation of pentamer can release infectious virus into the supernatant.
Effects of wool fibers on tribological behavior of friction materials (2014)

The effects of the wool fiber as reinforcement in the friction materials on the friction and wear properties were investigated in this study. The contents of the wool fiber in the friction materials tested were 0, 3, and 4 wt%. The friction tests were conducted with a constant friction tester at a temperature range of 100, 150, 200, 250, 300, and 350°C. The friction coefficient and wear rate were recorded. The friction coefficient of the friction materials reinforced with the wool fiber of 3 wt% was steady, and the wear rate was low. As the temperature increased, the stability of the friction coefficient of friction materials was improved. The Rockwell hardness decreased and the impact strength increased as the content of wool fibers was increased. The morphology of the worn surfaces was examined using scanning electron microscopy. The results indicated that the adhesive wear and abrasive wear were dominant in the friction materials reinforced with wool fiber.
Fully inkjet-printed two-dimensional material field-effect heterojunctions for wearable and textile electronics (2017)

Fully printed wearable electronics based on two-dimensional (2D) material heterojunction structures also known as heterostructures, such as field-effect transistors, require robust and reproducible printed multi-layer stacks consisting of active channel, dielectric and conductive contact layers. Solution processing of graphite and other layered materials provides low-cost inks enabling printed electronic devices, for example by inkjet printing. However, the limited quality of the 2D-material inks, the complexity of the layered arrangement, and the lack of a dielectric 2D-material ink able to operate at room temperature, under strain and after several washing cycles has impeded the fabrication of electronic devices on textile with fully printed 2D heterostructures. Here we demonstrate fully inkjet-printed 2D-material active heterostructures with graphene and hexagonal-boron nitride (h-BN) inks, and use them to fabricate all inkjet-printed flexible and washable field-effect transistors on textile, reaching a field-effect mobility of ~91 cm<sup>2</sup> V<sup>-1</sup> s<sup>-1</sup>, at low voltage (<5 V). This enables fully inkjet-printed electronic circuits, such as reprogrammable volatile memory cells, complementary inverters and OR logic gates.
Effects of Different Rollers and Rye Termination Methods on Soil Moisture and Cotton Production in a No-Till System (2020)

In the southern U.S., rollers/crimpers are used to terminate cover crops approximately 3 weeks before planting cotton when the cover crop reaches &gt; 90% termination. When spring is wet or cold, the 3-week period is reduced to keep recommended planting dates. A 3-year experiment was initiated in Alabama to determine the effectiveness of a 4-stage roller/crimper in increasing termination rates for cereal rye compared to 2-stage and spiral rollers/crimpers in rolling 1, 2, and 3 times over rye along with a single-pass smooth roller with glyphosate application. Effects of rye termination at 7, 14, and 21 days after rolling were assessed as were the effects on soil water conservation, cotton population, and yield. Seven days after rolling, the 4-stage, 2-stage, and spiral rollers rolling 3 times generated 96, 92, and 81% termination, respectively. Termination with the smooth roller with glyphosate was 94% and the control (no rolling) was 37%. At 14 days, termination among rollers was 91 to 98% and at 21 days no differences were found among rollers (99-100%). The 4-stage roller 3 times had the highest average soil volumetric water content (VWC) of 16.1%, whereas the spiral roller 1 time had the lowest (13.6%). Rolled rye had higher VWC content averaging 14.7% (12-cm surface layer) compared to the control (12.7%). Rolling treatments affected cotton emergence only in 2015; cotton population and yield were not affected. Seven days after rolling, the 4-stage and 2-stage roller/crimpers exceeded 90% rye termination making earlier cotton planting possible if required by climatic conditions.
A Robust Numerical Path Tracking Algorithm for Polynomial Homotopy Continuation (2020)

We propose a new algorithm for numerical path tracking in polynomial homotopy continuation. The algorithm is “robust” in the sense that it is designed to prevent path jumping, and in many cases it can be used in (only) double precision arithmetic. It is based on an adaptive stepsize predictor that uses Padé techniques to detect local difficulties for function approximation and danger for path jumping. We show the potential of the new path tracking algorithm through several numerical examples and compare it with existing implementations.
Inert gas permeation through homopolymer membranes (1974)

Abstract New data are reported for the permeation of inert gases through polyethylene, polytetrafluoroethylene, and silicone and natural rubbers. Additional data are compiled from the literature. The relative solubilities of these gases are practically insensitive to chemical variations in the homopolymer. Hence variations in structure at the glass transition ( T g ) and melting ( T m ) temperatures that affect diffusion also unambiguously affect permcation. Consequently an equivalence results between permeation at a given temperature for different polymers and permeation at different temperatures for a given polymer. Although the diffusion coefficient changes continuously with temperature, the Arrhenius parameters D o and E d apparently change discontinuously at T g and T m . Their magnitudes and variations with atomic weight reach maxima at about T g . These data indicate a dependence of the classical correlation between D o and E d on polymer properties. A perturbed diameter for the permeant, specific for each polymer, is proposed for correlating the D o and E d data. This correlation makes the changes observed at T g and T m more perceptible.
In vitro and in vivo Digestion of High‐Amylose Type Starch Granules (1989)

Abstract In vitro and in vivo digestion of high‐amylose type starch granules from sugary‐2 ( su 2 ), amylose‐extender ( ae ), and dull ( du ) maize endosperms by salivary and pancreatic α‐amylase of rats were investigated. From the results of in vitro starch granule digestion by both α‐amylases, we found a strong correlation between the starch‐granule digestibility and the wavelength at the maximum absorbance λ max , nm of the absorption spectra of starch‐iodine complexes. While the digestibility of the starch granules, which were isolated from the stomach, small intestine, and cecum of rats fed on diets containing either normal, su 2 , or ae starch‐granules, during passage through the mouth to the stomach of rats was calculated by using the regression equation obtained from the in vitro trials. We calculated 32–40,47–68, and 7–15% degradation of starch‐granules from normal, su 2 , and ae endosperms, respectively. The relative order of digestibility of starch‐granules in vivo was su 2 normal ae , respectively, which agrees with the previous in vitro studies.
Microbial cleavage of zearalenone (1988)

1. Zearalenone, a fungal oestrogenic compound, was subjected to microbial transformation studies. Preliminary screening with 150 fungal species showed that Gliocladium roseum was capable of metabolizing zearalenone in 80-90% yields. 2. Large-scale fermentation with G. roseum produced a 1:1 mixture of 1-(3,5-dihydroxyphenyl)-10'-hydroxy-1-undecen-6'-one and 1-(3,5-dihydroxyphenyl)-6'-hydroxy-1-undecen-10'-one. The compounds were isolated and purified at -20 degrees C, and identified using spectroscopic analysis and by comparison to products obtained from alkaline hydrolysis of zearalenone.
Security in mobile ad hoc and sensor networks: part I [Guest Editorial] (2008)

The seven papers in Part I of this Feature Topic focus on security on mobile ad hoc and sensor networks. The articles are summarized here.
Remotely pumped stimulated emission at 337 nm in atmospheric nitrogen (2013)

The realization of remotely pumped laser-like sources in the common air is an enabling step towards the development of new standoff sensing schemes in the atmosphere [1]. Although laser sources generating light in the opposite direction relative to that of the pumping radiation are particularly desirable, forward-emitting sources may also be useful. Pulsed backward-propagating laser emission at 845nm wavelength from atmospheric oxygen has been recently demonstrated [2]. The lasing scheme involved pumping by nanosecond deep-UV laser pulses at 226nm. An intense research effort is currently under way that targets the development of viable lasing schemes in another major constituent of air, nitrogen. Remote lasing in the atmospheric nitrogen under external laser pumping has been analyzed numerically and found feasible [3,4]. In 2003, it has been suggested that dilute plasma filaments that are produced through self-focusing of ultra-intense femtosecond infrared laser pulses in air emit weak directional laser-like radiation at the 357nm and 391nm transitions of neutral and singly-ionized nitrogen molecules, respectively [5]. Since 2003, those findings have not been independently confirmed. More recently, the observation of forward-propagating emission on various UV lines of singly ionized nitrogen molecules has been reported, under the conditions of pumping by tightly focused, tunable mid-IR femtosecond laser pulses [6]. The emission was found to be seeded by the spectral tail of the fifth harmonic of the pump.
Anesthetic Requirement Is Increased in Redheads (2004)

Red hair seems to be a distinct phenotype linked to anesthetic requirement in humans that can also be traced to a specific genotype.
Developing Nanocrystals for Cancer Treatment (2015)

Nanocrystals are carrier-free solid drug particles that are sized in the nanometer range and have crystalline characteristics. Due to high drug loading (as high as 100%) - free of organic solvents or solubilizing chemicals - nanocrystals have become attractive in the field of drug delivery for cancer treatment. Top-down and bottom-up approaches have been developed for preparing anticancer nanocrystals. In this review, preparation methods and in vivo performance of anticancer nanocrystals are discussed first, followed by an introduction of hybrid nanocrystals in cancer theranostics.
Numerical analysis of the unsteady flow inside wave rotors applied to air breathing engines. (1997)

Communication to : 13th international symposium on airbreathing engines (ISABE), Chattanooga, TN (USA), september 8-12, 1997
Molecular Heterogeneity of Metallocene Short-Chain Branched Polyethylenes and Their Fractions (2001)

A comparison on the molecular heterogeneity of two whole metallocene short-chain branched polyethylenes (SCBPEs) with different hexene comonomer (butyl branching) content and their Cross-Fractionated (CF) fractions has been made. As elucidated by differential scanning calorimetry (DSC) thermal segregation experiments and the subsequent isothermal crystallization kinetics investigations, the whole metallocene SCBPEs were found to possess both inter- and intramolecular heterogeneity. The crystallization kinetics of whole SCBPEs are substantially different for samples with or without a pre-multiple-step annealing treatment. For the CF fractions, the inter-molecular heterogeneity is not evident, but intra-molecular heterogeneity exists. Nevertheless, another self-induced SCBPE fraction, as a model sample, shows good homogeneity both inter- and intramolecularly. The crystal morphology observed via transmission electron microscopy (TEM) shows that multiple-step crystallized whole polymers exhibit large scale (molecularly) phase separation, whereas the CF fractions demonstrate microscopic (segmental) segregation only.
Optical Nonlinearities of Polymers (1988)

This talk will include selective results from our comprehensive program in nonlinear optical effects in organic molecules and polymers. We have calculated microscopic nonlinearities of organic molecules in several series of conjugated structures using ab-initio SCF approach coupled with the finite field method. The effects of increase in the II - electron conjugation length, molecular conformation, heavy atom effect and the role of substitutes have been investigated in order to derive an understanding of molecular structure-property relation so that structural parameters associated with enhanced optical nonlinearities can be identified. This theoretical study has been complemented with the measurements of optical nonlinearities in sequentially built and systematically derivatized structures.
Chain conformation of rod-like polymers in the melt: Small-angle neutron scattering of poly(benzoyl paraphenylene) (1998)

The chain conformation of a rigid rod polymer, poly(benzoyl paraphenylene), is determined in the melt using small-angle neutron scattering. The coherent scattering cross-section from blends of partially deuterated and hydrogenous poly(benzoyl paraphenylene) agree well with ideal rod scattering for q > 0.02 Å−1, indicating that the polymer chains are highly extended. Comparison of the results to a single chain-scattering function for chains of arbitrary stiffness yield a persistence length of ca. 130 Å. Pure component scattering at the lowest scattering lengths indicate that the melt is not molecularly homogenous, but is comprised of domains, potentially reflecting localized groupings of chains with similar backbone orientation. Furthermore, this mesoscopic structure depends on the processing history of the polymer in the melt state. © 1998 John Wiley & Sons, Inc. J. Polym. Sci. B Polym. Phys. 36: 2449–2459, 1998
The Role of Cell Death in Regulating the Size and Shape of the Mammalian Forebrain (1999)

The size of the cerebral cortex is determined by the rate of production of neurons and glial cells in the proliferative ventricular and subventricular zones. Recent studies from targeted mutations of different death-effector gene families indicate that programmed cell death (PCD) plays an important role in cell production and early morphogenesis of the mammalian forebrain before the formation of neuronal connections. For example, disruption of the c/Jun N-kinase signaling pathway by double-targeted mutation of both Jnk1 and Jnk2 results in increased PCD in the forebrain leading to precocious degeneration of cerebral precursors. In contrast, disturbance of the caspase cascade by targeted disruption of either casp-9 or casp-3 leads to decreased PCD causing expansion and exencephaly of the forebrain as well as supernumerary neurons in the cerebral cortex. The supernumerary neurons in these knockout mice align radially and form an expanded cortical plate which begins to form cerebral convolutions. Thus, the precise coordination of different apoptotic signaling pathways during early stages of neurogenesis is crucial for regulation of the proper cortical size and shape.
Field method for the detection of total petroleum hydrocarbon in water and soil samples (1997)

A new field GC/MS method for fast evaluation of total petroleum hydrocarbons is presented. It can be seen as a spin-off from our fast non target screening GC/MS analysis developed in the last years. This sum parameter evaluation of chromatographically unseparated multicompound mixtures is an additional favour of chromatographic methods on short GC columns. Straight forward sample preparation and analysis in less than 10 min make this method also interesting as substitution to common IR methods for hydrocarbon sum parameter estimation which use banned chlorinated solvents in large amounts.
Early response evaluation to neoadjuvant chemotherapy by FDG PET in patients with advanced ovarian cancer: Preliminary analysis (2006)

1707 Objectives: The aim of this study was to evaluate the role of sequential [18F]-Fluorodeoxyglucose Positron Emission Tomography (FDG PET) to predict the response to neoadjuvant chemotherapy in patients with advanced-stage ovarian cancer, and to establish the optimal timing to perform FDG PET. Methods: Ten patients with stage IIIC-IV ovarian cancer (serous papillary: 4/10;poorly differentiated adenocarcinoma: 6/10)were enrolled in the study (age range: 56-79; mean age: 67);they received 6 cycles of carboplatin and paclitaxel chemotherapy, followed by cytoreductive surgery. Total body FDG PET was acquired before therapy (baseline FDG PET) and after each cycle of therapy.Changes in tumoral FDG uptake, expressed as SUVmax,were compared with clinical and histopathologic response. The histopathologic response was assessed by expert pathologists; clinical response was evaluated every other cycle by clinical examination, CT scan, pelvic ultrasound and MRI. Serum CA 125 was measured at baseline and before each cycle of chemotherapy. This study was conducted after ethical clearance Results: All baseline FDG PET were positive. Four out of ten patients completed all cycles of therapy and underwent surgery. In three cases we observed a complete metabolic response, while one patient showed a partial response to treatment (Figure 1). A significant correlation was observed between FDG PET final results and histopathologic findings. A significant correlation was observed between SUVs max and histopathologic findings at the end of the therapy: responders showed a tumor regression grade of 3 or 4 (from 30% to 90% loss of tumour cells and > 90% loss of tumour cells, respectively). We found that the optimal timing for performing FDG PET during the treatment should be after the second or the third cycle of chemotherapy: a threshold of 55% decrease in SUV after the third cycle was found to reliably differentiate between metabolic responders and non responders. At this point of treatment, responsive patients showed a median SUV decrease of 74%; non responders had a median decrease of 10%. Conclusions: Despite some limitations, e.g. the small number of patients who completed all six cycles by now, this study shows that sequential FDG PET can be considered a reliable tool for early prediction of response to neoadjuvant chemotherapy in advanced-stage ovarian cancer. The optimal timing to perform FDG PET during the treatment should be after the second or the third cycle of chemotherapy, with a threshold of 55% decrease in SUV to reliably differentiate between metabolic responders and non responders.
Genetic Improvement @ ICSE 2020 (2020)

Following Prof. Mark Harman of Facebook's keynote and formal presentations (which are recorded in the proceed- ings) there was a wide ranging discussion at the eighth inter- national Genetic Improvement workshop, GI-2020 @ ICSE (held as part of the International Conference on Software En- gineering on Friday 3rd July 2020). Topics included industry take up, human factors, explainabiloity (explainability, jus- tifyability, exploitability) and GI benchmarks. We also con- trast various recent online approaches (e.g. SBST 2020) to holding virtual computer science conferences and workshops via the WWW on the Internet without face to face interac- tion. Finally we speculate on how the Coronavirus Covid-19 Pandemic will a ect research next year and into the future.
Human Simulated Intelligent Control for Permanent Magnet Synchronous Motor (2012)

This paper proposes a new speed control scheme for a Permanent Magnet Synchronous Motor(PMSM) by means of multi-mode control method,Human Simulate Intelligent Control. Similar to hierarchical intelligent control system,the proposed controller for PMSM is composed of three sections,Task Adapter Level (TA), Self-Tuning Level (ST) and Master Controller Level (MC).Simulation results clearly show that the controller guarantees the speed tracking errors asymptotically converge to zero despite time varying reference speed and load torque disturbance variation.Numerical simulations reveal the superiority of the proposed controller to traditional PI.
Myofibroblasts: A key promoter of tumorigenesis following radiofrequency tumor ablation (2022)

Radiofrequency ablation (RFA) of intrahepatic tumors induces distant tumor growth through activation of interleukin 6/signal transducer and activator of transcription 3 (STAT3)/hepatocyte growth factor (HGF)/tyrosine-protein kinase Met (c-MET) pathway. Yet, the predominant cellular source still needs to be identified as specific roles of the many types of periablational infiltrating immune cells requires further clarification. Here we report the key role of activated myofibroblasts in RFA-induced tumorigenesis and successful pharmacologic blockade. Murine models simulating RF tumorigenic effects on a macrometastatic tumor and intrahepatic micrometastatic deposits after liver ablation and a macrometastatic tumor after kidney ablation were used. Immune assays of ablated normal parenchyma demonstrated significantly increased numbers of activated myofibroblasts in the periablational rim, as well as increased HGF levels, recruitment other cellular infiltrates; macrophages, dendritic cells and natural killer cells, HGF dependent growth factors; fibroblast growth factor-19 (FGF-19) and receptor of Vascular Endothelial Growth Factor-1 (VEGFR-1), and proliferative indices; Ki-67 and CD34 for microvascular density. Furthermore, macrometastatic models demonstrated accelerated distant tumor growth at 7d post-RFA while micrometastatic models demonstrated increased intrahepatic deposit size and number at 14 and 21 days post-RFA. Multi-day atorvastatin, a selective fibroblast inhibitor, inhibited RFA-induced HGF and downstream growth factors, cellular markers and proliferative indices. Specifically, atorvastatin treatment reduced cellular and proliferative indices to baseline levels in the micrometastatic models, however only partially in macrometastatic models. Furthermore, adjuvant atorvastatin completely inhibited accelerated growth of macrometastasis and negated increased micrometastatic intrahepatic burden. Thus, activated myofibroblasts drive RF-induced tumorigenesis at a cellular level via induction of the HGF/c-MET/STAT3 axis, and can be successfully pharmacologically suppressed.