gebhart/patrepeval huggingface dataset:
A nonlinear auxetic structural vibration damper with metal rubber particles (2013)

The work describes the mechanical performance of a metal rubber particles (MRP) damper design based on an auxetic (negative Poisson's ratio) cellular configuration. The auxetic damper configuration is constituted by an anti-tetrachiral honeycomb, where the cylinders are filled with the MRP material. The MRP samples have been subjected to quasi-static loading to measure the stiffness and loss factor from the static hysteresis curve. A parametric experimental analysis has been carried out to investigate the effect of relative density and filling percentage on the static performance of the MRP, and to identify design guidelines for best use of MRP devices. An experimental assessment of the integrated auxetic-MRP damper concept has been provided through static and dynamic force response techniques.
Semiclassical theory of noise in semiconductor lasers - Part II (1983)

A model of semiconductor laser noise is presented which includes the carrier density as a dynamical variable and the carrier density dependence of the refractive index. The Van der Pol laser noise model is shown to he a special case of this treatment. Expressions are calculated for all laser spectra and compared with their Van der Pol counterparts. The power fluctuations spectrum and the frequency fluctuations spectrum exhibit a resonance corresponding to the relaxation resonance and the field spectrum contains fine structure, similar to sidebands which result from harmonic frequency modulation of a carrier signal. The role of carrier noise in determining the field spectrum linewidth is also considered.
Event-Based Receding Horizon Control for Two-Stages Multi-Product Production Plants (2006)

In this paper, we present a receding horizon control approach for multi-product production plants. Two-stage multi-product plants are considered. In the first stage, a set of parallel production lines generates intermediate products from raw materials. In the second stage, intermediate products are assembled together into final products through an assembly line. A set of buffers for the intermediate products connects the production lines and the assembly line and allows a continuous production flow. We propose a systematic event-based and control-oriented approach to this class of problems. We employ receding horizon control (RHC) techniques to control the production line flow in order to satisfy the time-varying request from the assembly line and optimize a certain performance criterion which includes the minimization of the intermediate products storage and the reduction of the processing time. Experimental data show the benefits deriving from the application of the proposed approach, to a process of car engine manufacturing
Angiography of Massive Hemorrhage Secondary to Pancreatic Disease (1977)

Twenty patients with massive abdominal hemorrhage related to chronic pancreatitis, pancreatic neoplasms and arteriovenous malformations were studied angiographically. Abdominal hemorrhage drained most frequently into the gastrointestinal tract, but also flowed through cutaneous drain sites and fistulas, intraperitoneally, into pseudocysts and once into a large pancreatic tumor. The most common angiographic observation in pancreatitis was pseudoaneurysm formation. Both patients with arteriovenous malformation had dilated, racemose feeding arteries and early dense filling of the draining veins. Three patients had pancreatic carcinoma and documented bleeding from gastroesophageal varices related to portal or splenic vein occlusion by the tumor. Five patients were treated by vasopressin infusion, balloon tamponade, or therapeutic embolization.
Multi-stage Er-doped fiber amplifier for gain-switched laser diodes (2011)

In this paper we present a picosecond fiber laser source with a 1 -MHz repetition rate based on an Er-doped fiber amplifier seeded by a gain-switched laser diode.
A review of the clinical relevance of mismatch‐repair deficiency in ovarian cancer (2008)

Ovarian cancer ranks fifth in both cancer incidence and mortality among women in the United States. Defects in the mismatch-repair (MMR) pathway that arise through genetic and/or epigenetic mechanisms may be important etiologically in a reasonable proportion of ovarian cancers. Genetic mechanisms of MMR dysfunction include germline and somatic mutations in the MMR proteins. Germline mutations cause hereditary nonpolyposis colorectal cancer (HNPCC), which is the third most common cause of inherited ovarian cancer after BRCA1 and BRCA2 mutations. An epigenetic mechanism known to cause inactivation of the MMR system is promoter hypermethylation of 1 of the MMR genes, mutL homolog 1 (MLH1). Various laboratory methods, in addition to clinical and histopathologic criteria, can be used to identify MMR-deficient ovarian cancers. Such methods include microsatellite instability analysis, immunohistochemistry, MLH1 promoter hypermethylation testing, and germline mutation analysis. In this review, the authors describe the existing literature regarding the molecular, clinical, and histologic characteristics of MMR-deficient ovarian cancers along with the possible effect on survival and treatment response. By further defining the profile of MMR-deficient ovarian cancers and their associated etiologic mechanisms, there may be a greater potential to distinguish between those of hereditary and sporadic etiology. The ability to make such distinctions may be of diagnostic, prognostic, and therapeutic utility.
Highly Sensitive, Flexible MEMS Based Pressure Sensor with Photoresist Insulation Layer (2017)

Pressure sensing is a crucial function for flexible and wearable electronics, such as artificial skin and health monitoring. Recent progress in material and device structure of pressure sensors has brought breakthroughs in flexibility, self-healing, and sensitivity. However, the fabrication process of many pressure sensors is too complicated and difficult to integrate with traditional silicon-based Micro-Electro-Mechanical System(MEMS). Here, this study demonstrates a scalable and integratable contact resistance-based pressure sensor based on a carbon nanotube conductive network and a photoresist insulation layer. The pressure sensors have high sensitivity (95.5 kPa<sup>-1</sup> ), low sensing threshold (16 Pa), fast response speed (<16 ms), and zero power consumption when without loading pressure. The sensitivity, sensing threshold, and dynamic range are all tunable by conveniently modifying the hole diameter and thickness of insulation layer.
Five decades of healthcare simulation (2017)

In this paper we have not attempted to produce any kind of systematic review of simulation in healthcare to compete with the dozen (at least) excellent and comprehensive survey papers on this topic that already exist. We begin with a glance back at the early days of Wintersim, but then proceed, in line with the theme of this special track, to reflect on general developments in healthcare simulation over the years from our own personal perspectives. We include some memories and reflections by several pioneers in this area, both academics and healthcare practitioners, on both sides of the Atlantic. We also asked four current simulation modelers, who all specialize in healthcare applications but from very diverse perspectives, to reflect on their experiences. We endeavor to identify some common or recurring themes across the years, and end with a glimpse into the future.
Bacterial remediation from effluent containing multi-walled carbon nanotubes (2011)

Multi-wall carbon nanotubes (MWCNT) were functionalized with functional groups containing oxygen, mainly carboxylic groups (-COOH), through reaction with a mixture of H2SO4/HNO3 (3:1 v/v). The oxidized multi-wall carbon nanotubes (MWCNTOOH) were used to prepare an effluent, 2 mg L−1 in a saline solution of NaCl (0.9%), to study of remediation of MWCNTOOH in aqueous suspension by utilization of Escherichia coli. The suspensions of E. coli (4.5 × 105 CFU mL−1 and 4.5 × 108 CFU mL−1) in test tubes with MWCNTOOH effluent caused the precipitation of a large amount of MWCNTOOH and supernatant clearing. The scanning electron microscopy (SEM) analysis of the precipitate and supernatant showed the adhesion and interlace of MWCNTOOH in bacteria surface. Although the precipitate consist of a large quantity of MWCNTOOH and bacteria, it was verified their presence in the supernatant. The spread plate technique showed that MWCNTOOH caused no cellular death of E. coli in the supernatant.
Serious Bacterial Infections in Hospitalized Febrile Infants in the First and Second Months of Life (2017)

In HR infants, higher SBI rates were associated with younger age, higher body temperature and thrombocytopenia. In contrast, SBI (mostly urinary tract infection) rates among LR infants (approximately 10%) were not associated with these factors.
ChemInform Abstract: REACTIONS OF TRIPLET DIPHENYLCARBENE BY HYDROGEN ATOM TUNNELING IN RIGID MEDIA (1983)

Abstract Photolytisch aus Diphenyldiazomethan bei 77 K in 2‐Propanol (IIa) erzeugtes Titelcarben (I) spaltet aus der Matrix H‐Atome ab, so daß die Produkte (IIIa)‐(Va) entstehen.
Comparison of Omadacycline and Tigecycline Pharmacokinetics in the Plasma, Epithelial Lining Fluid, and Alveolar Cells of Healthy Adult Subjects (2017)

The steady-state concentrations of omadacycline and tigecycline in the plasma, epithelial lining fluid (ELF), and alveolar cells (AC) of 58 healthy adult subjects were obtained. Subjects were administered either omadacycline at 100 mg intravenously (i.v.) every 12 h for two doses followed by 100 mg i.v. every 24 h for three doses or tigecycline at an initial dose of 100 mg i.v. followed by 50 mg i.v. every 12 h for six doses. A bronchoscopy and bronchoalveolar lavage were performed once in each subject following the start of the fifth dose of omadacycline at 0.5, 1, 2, 4, 8, 12, or 24 h and after the start of the seventh dose of tigecycline at 2, 4, 6, or 12 h. The value of the area under the concentration-time curve (AUC) from time zero to 24 h postdosing (AUC<sub>0-24</sub>) (based on mean concentrations) in ELF and the ratio of the ELF to total plasma omadacycline concentration based on AUC<sub>0-24</sub> values were 17.23 mg · h/liter and 1.47, respectively. The AUC<sub>0-24</sub> value in AC was 302.46 mg · h/liter, and the ratio of the AC to total plasma omadacycline concentration was 25.8. In comparison, the values of the AUC from time zero to 12 h postdosing (AUC<sub>0-12</sub>) based on the mean concentrations of tigecycline in ELF and AC were 3.16 and 38.50 mg · h/liter, respectively. The ratio of the ELF and AC to total plasma concentrations of tigecycline based on AUC<sub>0-12</sub> values were 1.71 and 20.8, respectively. The pharmacokinetic advantages of higher and sustained concentrations of omadacycline compared to those of tigecycline in plasma, ELF, and AC suggest that omadacycline is a promising antibacterial agent for the treatment of lower respiratory tract bacterial infections caused by susceptible pathogens.
Increased frequency of minimal homozygous deletions is associated with poor prognosis in primary malignant melanoma patients (2014)

Identification of prognostic melanoma-associated copy number alterations (CNAs) is still an area of active research. Here, we investigated by high-resolution array comparative genomic hybridization (aCGH) a cohort of 31 paraffin-preserved primary malignant melanomas (MMs), whose prognosis was not predictable on the basis of conventional histopathological parameters. Although we identified a variety of highly recurrent sites of genomic lesions, the total number of CNAs per patient was not a discriminator of MM outcome. Furthermore, validation of aCGH by quantitative PCR on an extended population of 65 MM samples confirmed the absence of predictive value for the most recurrent CNA loci. Instead, our analysis revealed specific prognostic potential of the frequency of homozygous deletions (representing less than 3% of the total CNAs on average per sample), which was strongly associated with sentinel lymph node (SLN) invasion (P = 0.003), and distant metastasis (P = 0.003). Increased number of homozygous deletions was also indicative of poor patient survival (P = 0.01), both in our samples and in an independent validation of public dataset of primary and metastatic MMs. Moreover, we identified 77 hotspots of minimal common homozygous deletions, enriched in genes involved in cell adhesion processes and cell-communication functions, which preferentially accumulated in primary MMs showing the most severe outcome. Therefore, specific loss of gene loci in regions of minimal homozygous deletion may represent a pivotal type of genomic alteration accumulating during MM progression with potential prognostic implication.
High expression of HSP47 in ulcerative colitis-associated carcinomas: proteomic approach (2009)

These results suggest that overexpression of HSP47 is a unique characteristic of UC-associated carcinoma related to type I collagen synthesis, with possible clinical applications.
Simplified ohmic and Schottky contact formation for field effect transistors using the single layer integrated metal field effect transistor (SLIMFET) process (1995)

A new III-V semiconductor device fabrication process for GaAs-based field effect transistors (FET) is presented which uses a single lithographic process and metal deposition step to form both the ohmic drain/source contacts and the Schottky gate contact concurrently. This single layer integrated metal FET (SLIMFET) process simplifies the fabrication process by eliminating an additional lithographic step for gate definition, a separate gate metallization step, and thermal annealing for ohmic contact formation. The SLIMFET process requires a FET structure which incorporates a compositionally graded In/sub x/Ga/sub 1-x/As cap layer to form low resistance, nonalloyed ohmic contacts using standard Schottky metals. The SLIMFET process also uses a Si/sub 3/N/sub 4/ mask to provide selective removal of the InGaAs ohmic layers from the gate region prior to metallization without requiring an additional lithographic step. GaAs MESFET devices were fabricated using this new SLIMFET process which achieved DC and RF performance comparable to GaAs MESFET's fabricated by conventional methods.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Supplementary Table 3 from A Novel Compound, NK150460, Exhibits Selective Antitumor Activity against Breast Cancer Cell Lines through Activation of Aryl Hydrocarbon Receptor (2023)

&lt;p&gt;Supplementary Table 3. Analysis of gene expression with microarray in NK150460 treated breast cancer cell lines.&lt;/p&gt;
More Efficient Oblivious Transfer Extensions with Security for Malicious Adversaries. (2015)

Oblivious transfer (OT) is one of the most fundamental primitives in cryptography and is widely used in protocols for secure two-party and multi-party computation. As secure computation becomes more practical, the need for practical large scale oblivious transfer protocols is becoming more evident. Oblivious transfer extensions are protocols that enable a relatively small number of \base-OTs to be utilized to compute a very large number of OTs at low cost. In the semi-honest setting, Ishai et al. (CRYPTO 2003) presented an OT extension protocol for which the cost of each OT (beyond the base-OTs) is just a few hash function operations. In the malicious setting, Nielsen et al. (CRYPTO 2012) presented an ecient OT extension protocol for the setting of active adversaries, that is secure in the random oracle model. In this work, we present an OT extension protocol for the setting of malicious adversaries that is more ecient and uses less communication than previous works. In addition, our protocol can be proven secure in both the random oracle model, and in the standard model with a type of correlation robustness. Given the importance of OT in many secure computation protocols, increasing the eciency of OT extensions is another important step forward to making secure computation practical.
The oscillatory pipe flow with arbitrary wall injection (2002)

The linearized Navier–Stokes equations play a central role in describing the unsteady motion of a viscous fluid inside a porous tube. Asymptotic solutions of these equations have been found and here we extend the class of known solutions by solving the problem for an arbitrary mean–flow function of the Berman type. In the process, we show how not only do we recover, confirm, or correct some of the previously known solutions, but also find some completely new forms. It is interesting that, for sufficiently small injection, the Sexl profile can be restored from ours. Furthermore, we find that analytical, numerical and experimental results obtained by other investigators compare favourably with ours. The methods we apply provide accurate expressions for the main flow variables and help describe the ensuing oscillatory field. By appealing to a space–reductive multiple–scale technique, the problem's underlying length–scale is rigorously derived. Our results indicate that, irrespective of the mean–flow details, the unsteady component of vorticity initiated by small pressure disturbances can be more intense than its mean counterpart. No vortical study in porous tubes can therefore be complete unless it incorporates the unsteady field contribution.
Design of Mixed PEO/PAA Brushes with Switchable Properties Toward Protein Adsorption (2012)

Adsorption of proteins at interfaces is an ubiquitous phenomenon of prime importance. Layers of poly(ethylene oxide) (PEO) are widely used to repel proteins. Conversely, proteins were shown to adsorb deeply into brushes of poly(acrylic acid) (PAA), and their subsequent partial release could be triggered by a change of pH and/or ionic strength (I). Mixed brushes of these polymers are thus promising candidates to tune protein adsorption onto new smart surfaces. In this work, the synthesis of such mixed brushes was performed based on a "grafting to" approach, the two polymers being either grafted sequentially or simultaneously. Detailed characterization of the obtained brushes using static water contact angle measurements, X-ray photoelectron spectroscopy, electrochemical impedance spectroscopy, and polarization-modulation reflection-absorption infrared spectroscopy is presented. While sequential grafting of the two polymers for different reactions times did not give rise to a broad range of composition of mixed brushes, simultaneous grafting of the polymers from solutions with different compositions allows for the synthesis of a range of mixed brushes (mass fraction of PEO in the mixed brushes from 0.35 to 0.65). A key example is then chosen to illustrate the switchable behavior of a selected mixed PEO/PAA brush toward albumin adsorption. The adsorption behavior was monitored with a quartz crystal microbalance. The mixed brush could adsorb high amounts of albumin, but 86% of the adsorbed protein could then be desorbed upon pH and I change. The obtained properties are thus a combination of the ones of PEO and PAA, and a highly switchable behavior is observed toward protein adsorption.
Exploring the orthorhombic–tetragonal phase transition in CH3NH3PbI3: the role of atom kinetics (2017)

Methylammonium lead tri-iodide is a polymorphic material with two temperature-induced phase transitions at 165 K and 327 K, accompanied by an orthorhombic-to-tetragonal and a tetragonal-to-cubic lattice modification. Understanding the origins of these transitions as well as their implications on the crystal structure of the material is fundamental for its technological optimization. Here, we use the density functional theory along with ab initio molecular dynamics to study the low-temperature phase transition of CH<sub>3</sub>NH<sub>3</sub>PbI<sub>3</sub>. Considering two kinetically robust models for the orthorhombic and the tetragonal phase, we show that the vibrational features of the material can be strongly affected by the orientations of the methylammonium ions. We argue that the orthorhombic-tetragonal transition is characterized by a partial rearrangement of the organic cations that locally relaxes the stress induced by the thermal movement of atoms. We finally propose a macroscopic model for the tetragonal phase that consists of rotated noncentrosymmetric domains, where the methylammonium ions are quasi-two-dimensionally confined around the a-b crystallographic plane.
PLM as a strategy for the management of heterogeneous information in bio-medical imaging field (2016)

The amount of heterogeneous information that researchers in bio-medical imaging (BMI) field have to manage has grown significantly, and their costs remain high. Large-scale sharing and reusing of this information has become unavoidable. Some data management systems have been developed in neuroimaging field, however they miss to integrate the data provenance all along the research works, from study specifications to scientific publication. The manufacturing industry was confronted to similar issues twenty years ago and designed product lifecycle management (PLM) systems to properly share and manage product information all along its lifecycle and among project teams. Therefore, PLM systems are proposed to be a relevant strategy to manage BMI research studies information. The generic, flexible and PLM-oriented data model called BMI-lifecycle management (BMI-LM) is described, as well as a neuroimaging classification which brings flexibility to the information management system. A test implementation into a PLM system is presented, and the feedback from the GIN researchers is discussed.
Thrombocytopenia following liver transplantation is associated with platelet consumption and thrombin generation (1997)

Thrombocytopenia frequently occurs immediately after orthotopic liver transplantation. We have investigated the cause of this phenomenon in a cohort of 45 consecutive liver transplant recipients. The median preoperative platelet count (range) of 129 x 10(9)/l (14-719) fell to 56 x 10(9)/l (23-334) by the fourth postoperative day. The median preoperative reticulated platelet percentage (range) of 6.7% (2.2-23.9) increased to 16.4% (4.6-40.8) on day 7. There was a significant rise in prothrombin fragment F1.2 by the first postoperative day which was followed by rises in fibrinogen and fibrin degradation products. There was no increase in platelet-associated immunoglobulin or markers of endothelial activation. We conclude that there is an increased rate of platelet consumption associated with thrombin generation that reflects the magnitude of liver transplant surgery.