gebhart/patrepeval huggingface dataset:
Athlete's Heart in Asian Military Males: The CHIEF Heart Study (2021)

<b>Background:</b> Elite athlete's heart is characterized by a greater left ventricular mass indexed by body surface area (LVMI) and diastolic function; however previous studies are mainly conducted in non-Asian athletes compared to sedentary controls. <b>Methods:</b> This study included 1,388 male adults, aged 18-34 years, enrolled in the same unified 6-month physical training program in Taiwan. During the midterm exams of 2020, all trainees completed a 3-km run (endurance) test, and 577 were randomly selected to attend a 2-min push-up (muscular strength) test. Elite athletes were defined as the performance of each exercise falling one standard deviation above the mean (16%). Cardiac structure and function were measured by echocardiography and compared between elite and non-elite athletes. Multiple logistic regression analysis was used to determine the independent predictors of elite athlete status at each exercise modality. <b>Results:</b> As compared to non-elite controls, elite endurance athletes had greater LVMI (84.4 ± 13.6 vs. 80.5 ± 12.9 g/m<sup>2</sup>, <i>p</i> < 0.001) and lateral mitral E'/A' ratio (2.37 ± 0.73 vs. 2.22 ± 0.76, <i>p</i> < 0.01) with lower late diastolic A' (7.77 ± 2.16 vs. 8.30 ± 3.69 cm/s, <i>p</i> = 0.03). Elite strength athletes had greater LVMI (81.8 ± 11.4 vs. 77.5 ± 12.1, <i>p</i> = 0.004) and lateral mitral E'/A' ratio (2.36 ± 0.70 vs. 2.11 ± 0.71, <i>p</i> < 0.01) with a greater early diastolic E' (19.30 ± 4.06 vs. 18.18 ± 4.05 cm/s, <i>p</i> = 0.02). Greater LVMI and lower heart rate were independent predictors of elite endurance athletes [odds ratio (OR) and 95% confidence intervals: 1.03 (1.02, 1.04) and 0.96 (0.95, 0.98), respectively]. Greater LVMI, lateral mitral E'/A' ratio and right ventricular systolic pressure were independent predictors of elite strength athletes [OR: 1.03 (1.01, 1.05), 1.50 (1.06, 2.12), and 1.12 (1.05, 1.19), respectively]. <b>Conclusions:</b> Cardiac structural and functional characteristics differ between endurance and strength elite athletes. While greater LVMI predicts elite status in both groups of Asian athletes, consistent with findings from Western elite athletes, greater diastolic function, and right ventricular systolic pressure characterize strength elite athletes, while lower heart rate at rest predicts endurance elite athletic status.
Verification of Resistance Prevalence in Bacterial Pathogens by the Nationwide Surveillance Conducted by the Japanese Society of Chemotherapy (JSC) (2008)

Background: JSC collects comprehensive data on susceptibilities of the major bacterial pathogens in adult respiratory tract infections (RTI), annually, by the nationwide surveillance program from 2006. Comparison of the data for isolates in 2007 with those in 2006 enabled us to verify the resistance tendency of the pathogens. Here we report unique characteristics of antimicrobial resistance among Japanese bacterial pathogens in adult RTI. Methods: A total of evaluative 1,102 isolates of six major pathogens (226 Staphylococcus aureus, 257 Streptococcus pneumoniae, 206 Haemophilus influenzae, 120 Moraxella catarrhalis, 122 Klebsiella pneumoniae, 171 Pseudomonas aeruginosa) collected from well-diagnosed adult RTI patients at 39 hospitals throughout Japan were subjected to this study. Susceptibilities of these strains to 45 antimicrobial agents of various classes were tested at the central laboratory according to CLSI standards for broth microdilution method. Beta-lactamases were detected by the Nitrocefin disc methods. Extended-spectrum beta-lactamase (ESBL) and metallo-beta-lactamase (MBL) were distinguished by the Cica-Beta Test. Panton-Valentaine-Leukocidin (PVL) gene in S.aureus was sought by PCR method. Results: In S.aureus, 135 strains (59.7%) were found to be MRSA. Under stratifications, incidences of MRSA that 125/201 (62.2%) in inpatients compared to 10/25 (40.0%) in outpatients, and that 90/119 (75.6%) in nosocomial pneumonia to 23/61 (37.7%) in CAP and to 13/28 (46.4%) in AECB were significantly different. No PVL-positive strain was found among 226 S.aureus isolates. In S.pneumoniae, 91 strains (35.4%) were penicillin-non-susceptible (78 PISP, 13 PRSP) but no difference was found under stratifications. In H.influenzae, 115 strains (55.8%) including 60 BLNAR strains (29.1%) were ampicillin-non-susceptible with a significantly high prevalence (79/128, 61.7%) in those isolated from inpatients. No ESBL-producing strain was found in K.pneumoniae and two MBL-producer were found in P.aeruginosa. Conclusion: Based on two yearly surveillances the resistance tendency of major bacterial pathogens in adult RTI were well elucidated.
Comparison of background normalization methods for text-independent speaker verification (1997)

This paper compares two approaches to background model representation for a text-independent speaker verification task using Gaussian mixture models. We compare speaker-dependent background speaker sets to the use of a universal, speaker-independent background model (UBM). For the UBM, we describe how Bayesian adaptation can be used to derive claimant speaker models, providing a structure leading to significant computational savings during recognition. Experiments are conducted on the 1996 NIST Speaker Recognition Evaluation corpus and it is clearly shown that a system using a UBM and Bayesian adaptation of claimant models produces superior performance compared to speaker-dependent background sets or the UBM with independent claimant models. In addition, the creation and use of a telephone handset-type detector and a procedure called hnorm is also described which shows further, large improvements in verification performance, especially under the difficult mismatched handset conditions. This is believed to be the first use of applying a handset-type detector and explicit handset-type normalization for the speaker verification task.
Analysis and simulation of a 6.7 GHz coaxial Bragg reflector (2007)

A coaxial line periodically loaded by circular disks on the inner conductor is designed to act as Bragg reflector in the 4.0–10.0 GHz frequency range. This is achieved by placing 10 disks (0.35 cm thick and 6.22 cm in diameter) equally spaced by the periodic distance of 1.8 cm on a coaxial waveguide with inner and outer diameter of 6.90 cm and 4.22 cm. Analytical discussion followed by 2D and 3D computer simulations demonstrate a bandgap of 5.6 GHz centered at the 6.7 GHz design frequency
Abstract 17097: A Novel Brain Injury Biomarker Correlates With Cyanosis in Infants With Congenital Heart Disease (2016)

Introduction: Cyanotic heart lesions are a complex subset of congenital heart disease (CHD) in which patients are persistently desaturated until surgical repair/palliation. Hypothesis: We hypothesized there will be a direct relationship between degree of preoperative desaturation and presence of systemic inflammation, as well as evidence of brain injury in children less than one year of age. We further hypothesized that preoperative desaturation with augmented systemic inflammation will predict a more complex postoperative course. Methods: Fifty patients with CHD were enrolled in this study and classified as cyanotic (O 2 ≤90%) or acyanotic (O 2 >90%) based on SpO 2 . Serum was obtained within 2 weeks of the cardiac surgery and the following inflammatory mediators were analyzed using commercially available ELISA kits: macrophage migration inhibitory factor, IL-6, IL-8, TNF-α, IL-12p70, IL-10, IL-1β, and INF-γ; and a novel biomarker of axonal injury, phosphorylated high-molecular weight neurofilament (pNF-H). Postoperative variables included inotrope score, duration of mechanical ventilation and length of stay. Results: A total of 22 cyanotic and 28 acyanotic patients were enrolled with a median age of 9.5 days (range 2-303 days) and 99.5 days (range 1-274 days), respectively; and a mean ± SD SpO 2 of 78 ± 18% and 97 ± 3% (p Conclusions: Cyanotic patients with CHD were exposed to higher serum concentrations of inflammatory mediators in the preoperative period compared to acyanotic patients, and showed evidence of brain injury. The severity of preoperative desaturation was a significant predictor of greater postoperative medical intervention.
Noise measurement evaluation of takeoff and approach profiles optimized for noise abatement (1971)

Noise measurement evaluation of takeoff and approach profiles optimized for noise abatement
Genetic Relationships among Different Chemotypes of Lupinus sulphureus (2018)

Lupines (Lupinus spp.) are a common plant legume species found on western U.S. rangelands. Lupinus spp. may contain quinolizidine and/or piperidine alkaloids that can be toxic and/or teratogenic to grazing livestock. Alkaloid profiles may vary between and within a species. The objectives of this study were to (1) further explore the characteristic alkaloid profiles of Lupinus sulphureus using field collections and (2) explore the phylogenetic relationship of the different populations and chemotypes of L. sulphureus using the amplified fragment length polymorphism method of DNA fingerprinting, thus providing possible explanations to the phenomena of multiple chemotypes within a species. A total of 49 accessions of L. sulphureus were classified into seven chemotypes. The DNA profiles showed that one L. sulphureus chemotype, chemotype A, is genetically divergent from the other chemotypes of L. sulphureus, suggesting that it represents an unresolved lupine taxon, possibly a new lupine species. Additionally, the different chemotypes of L. sulphureus represented different genetic groups, as shown by Bayesian cluster analysis and principle component analysis.
Failure of 500 mg of ceftriaxone to eradicate pharyngeal gonorrhoea, Australia (2013)

Over time Neisseria gonorrhoeae has developed resistance to a wide range of antimicrobials, including cephalosporins, limiting treatment options.We report a case of persistent pharyngeal N. gonorrhoeae despite administration of 500 mg of ceftriaxone by intramuscular injection, a dose exceeding that currently recommended in some countries for gonorrhoea. We obtained informed consent from the index patient to publish this report...
Three-dimensional molecular dynamics analysis of processing using a pin tool on the atomic scale (2000)

A three-dimensional model of molecular dynamics (MD) is proposed to study the effects of tool geometry and processing resistance on the atomic-scale cutting mechanism. The model includes the utilization of the Morse potential function to simulate the interatomic force between the workpiece and a tool. The results show that the cutting resistance increases with the angle of the pin tool and the depth of cut, and the cutting force is essentially constant over the range of velocities simulated. In addition, the obtained cutting resistance of present MD simulation exhibits an evident relationship to the ratio of the vertical and the horizontal contact area between the tool and the workpiece within the range of a pin angle of 90-150°. Finally, work hardening and stick-slip phenomena during the process are also observed.
Material classification using basis material decomposition from spectral x-ray CT (2022)

Abstract Purpose: Spectral CT exploits advanced MultiX ME 100 photon counting detectors (PCD) to measure a material’s spectrally resolved linear attenuation coefficient (LAC) with the simultaneous spectral acquisition at multiple energy thresholds. We present a method for material classification using spectral x-ray Computed Tomography (CT). Methods: The method employs a basis material decomposition model and estimates the effective atomic number (Z eff ) from the spectral LAC measurements. Basis material decomposition builds on the fact that the LAC of any material can be well approximated by a linear combination of equivalent thicknesses of basis materials, with known and typically Z eff values at the extremes of the relevant Z eff range. Spectral distortions of the energy spectrum due to the physical interactions between photons and the multi-energy-bin PCD such as charge sharing and photon pileup are corrected by a spectral correction algorithm. The validation of the method has been performed with experimental data acquired with a custom laboratory instrument for spectral CT, examining “real life” phantoms with materials in the range of 6 ≤ Z eff ≤ 15. Results: With optimized parameters the data was collected from 12 projections and rebinned from 128 into 15 energy bins, two basis materials were used for the decomposition. In that case the classification method gives a relative deviation of 2.4% for Z eff , while this deviation is 5.2% when spectral correction is not used. Conclusion: The classification method is now ready for use in security screening where modern spectral CT systems are employed.
A SIMULATION METHOD OF VEHICLE MODEL COUPLING WITH DUMMY IN SIDE IMPACT (1991)

This paper demonstrates a simulation model for the proposed National Highway Traffic Safety Administration (NHTSA) side impact test using a large vehicle Finite Element Method (FEM) including two occupant models. The calculation of the model is performed, based on the results of several dynamic tests of various components and full-scale vehicles. The paper presents modeling results which satisfactorily correlate to actual tests. (A) For the covering abstract of the conference see IRRD 864606.
Video super-resolution by integrating SAD and NCC matching criterion for multiple moving objects (2008)

Traditionally, image enlargement is magnified from a single image. Due to the one and only one image, the quality of the reconstructed image is thus constrained. Super-resolution is proposed to use multiple frames as additional information to estimate the high-resolution image. If we have enough low-resolution images with observed subpixels, the high-resolution image can be reconstructed. In this paper, a complete super-resolution model based on k-means motion clustering is proposed for image enlargement with multiple moving objects. Motion masks are first produced for useful image selection and then blocks matching are used to do motion estimation. Two complementary features, sum of absolute difference (SAD) and normalized cross-correlation (NCC), are adopted as the matching criterion. Objects are assumed to move slightly between two consecutive images. Thus, erroneous motion vectors could be corrected by the center of motion clusters. The proposed method achieves better magnification quality than the traditional ones and some previous super resolution works. From the experimental results, both the visual and quantitative improvements, especially in the high frequency, are significant.
Ray tracing trimmed rational surface patches (1990)

This paper presents a new algorithm for computing the points at which a ray intersects a rational B&amp;eacute;zier surface patch, and also an algorithm for determining if an intersection point lies within a region trimmed by piecewise B&amp;eacute;zier curves. Both algorithms are based on a recent innovation known as B&amp;eacute;zier clipping, described herein. The intersection algorithm is faster than previous methods for which published performance data allow reliable comparison. It robustly finds all intersections without requiring special preprocessing.
Improvements in magnetic resonance imaging excitation pulse design (2008)

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2008.
Étude du mécanisme de résistance à l'actinomycine D chez une lignée de cellules de hamster syrien (1972)

Des lignées dérivées de la souche CL2TSV5, clonée d'une tumeur de Hamster ont acquis la résistance a des concentrations de 1 à 4 ug/ml d'actinomycine D (AMD) par exposition continue à des doses croissantes de l'antibiotique. Les cellules de ces lignées ont un taux de croissance beaucoup plus lent que les cellules de la souche parentale, ce qui se répercute dans les taux de synthèse plus faibles des macromolécules cellulaires, ADN, ARN et protéines. Par détermination de la radioactivité dans la fraction soluble au TCA, nous avons noté que la pénétration dans la cellule de l'uridine-3H était plus lente chez les cellules résistantes, ce qui nous fit supposer que les membranes* de ces cellules avaient subi des modifications importantes lors de l'acquisition de la résistance â l'AMD-3H. À partir d'expériences de résistance croisée où il fut mis en évidence que la résistance â l'AMD était accompagnée d'une résistance à la puromycine mais non d'une résistance à la cytosine arabinoside, nous avons émis l'hypothèse que la résistance à l'AMD chez les lignées étudiées, devait être causée par une imperméabilité sélective à l'AMD au niveau de la membrane cellulaire. Des cinétiques d'incorporation d'AMD- H confirmèrent cette hypothèse car le marquage se retrouve en quantité 100 fois moins grande dans la fraction soluble au TCA obtenue de cellules résistantes en comparaison de celle obtenue de cellules sensibles. L'inhibition de la croissance d'un certain % de cellules dans la population résistante semble être due à la moins grande imperméabilité de ces cellules à l'antibiotique, résultant de l'action de la trypsine. * Le terme membranes cellulaires sera employé dans cette étude dans le sens large de membranes (double feuillet phospholipidique) et "cell coat" ou surface. Les quelques exceptions seront indiquées.
Biorobots, Nonlinear Dynamics and Perception (2008)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
Crystal structures of the dioxane hemisolvates ofN-(7-bromomethyl-1,8-naphthyridin-2-yl)acetamide and bis[N-(7-dibromomethyl-1,8-naphthyridin-2-yl)acetamide] (2017)

The syntheses and crystal structures of <i>N</i>-(7-bromo-methyl-1,8-naphthyridin-2-yl)acetamide dioxane hemisolvate, C<sub>11</sub>H<sub>10</sub>BrN<sub>3</sub>O·0.5C<sub>4</sub>H<sub>8</sub>O<sub>2</sub>, (I), and bis-[<i>N</i>-(7-di-bromo-methyl-1,8-naphthyridin-2-yl)acetamide] dioxane hemisolvate, 2C<sub>11</sub>H<sub>9</sub>Br<sub>2</sub>N<sub>3</sub>O·0.5C<sub>4</sub>H<sub>8</sub>O<sub>2</sub>, (II), are described. The mol-ecules adopt a conformation with the N-H hydrogen pointing towards the lone electron pair of the adjacent naphthyridine N atom. The crystals of (I) are stabilized by a three-dimensional supra-molecular network comprising N-H⋯N, C-H⋯N and C-H⋯O hydrogen bonds, as well as C-Br⋯π halogen bonds. The crystals of compound (II) are stabilized by a three-dimensional supra-molecular network comprising N-H⋯N, C-H⋯N and C-H⋯O hydrogen bonds, as well as C-H⋯π contacts and C-Br⋯π halogen bonds. The structure of the substituent attached in the 7-position of the naphthyridine skeleton has a fundamental influence on the pattern of inter-molecular noncovalent bonding. While the Br atom of (I) participates in weak C-Br⋯O<sub>guest</sub> and C-Br⋯π contacts, the Br atoms of compound (II) are involved in host-host inter-actions <i>via</i> C-Br⋯O=C, C-Br⋯N and C-Br⋯π bonding.
Multilineage mobilization of peripheral blood progenitor cells in humans following administration of PEG‐rHuMGDF (1997)

The most important physiological regulator of megakaryocytopoiesis is the ligand for the c-mpl receptor (thrombopoietin/megakaryocyte growth and development factor, MGDF). We examined the effect of pegylated-recombinant human MGDF (PEG-rHuMGDF): patients received PEG-rHuMGDF at doses of 0.03, 0.1, 0.3 or 1.0 microg/kg/d or placebo for 10d maximum in a double-blinded randomized study. There was a dose-dependent elevation in circulating platelet counts but no alteration in erythrocyte or total leucocyte counts. The number of bone marrow megakaryocytes was increased approximately 2-fold. The frequency of bone marrow progenitor cells was not altered. In contrast, both to the bone marrow results and to published pre-clinical data, there was a dose-dependent mobilization into the blood of progenitor cells of multiple cell lineages. Increased levels of Meg-CFC (maximum increase 30-fold), day 7 and day 14 GM-CFC and BFU-E were demonstrated at doses of 0.3 and 1.0 microg/kg/d PEG-rHuMGDF. At 0.1 microg/kg/d, mobilization of Meg-CFC alone occurred in two-thirds of patients. Maximum blood levels of progenitor cells occurred at day 12. Thus, administration of PEG-rHuMGDF to humans resulted in mobilization of progenitor cells of multiple lineages despite its 'lineage-specific' activity on mature cell development.
Optimisation methods for adaptive optics in microscopy (2005)

This paper is about optimisation methods for adaptive optics in microscopy. It was presented at the Focus on Microscopy conference in 2005.
A New Synthesis of the Potent and Selective Anti-Herpesvirus Agent (S)-1-[3-Hydroxy-2-(Phosphonylmethoxy)Propyl]Cytosine (1990)

Abstract A new synthetic approach to (S)-1-[3-hydroxy-2-(phosphonyl-methoxy)propyl]cytosine (3, (S)-HPMPC) is based on coupling of the heterocyclic moiety with a glycerol-derived side chain, followed by introduction of the phosphonylmethyl ether group.
Cepstrum discrimination function (Corresp.) (1975)

An expression is derived for the function that governs the discrimination by the power cepstrum against components at large time delays. The function has been found to be useful in normalizing cepstrum displays.
A Data-Driven Approach For Actuator Servo Loop Failure Detection (2017)

International audience
Testing of high-speed DACs using PRBS generation with &#x201C;Alternate-Bit-Tapping&#x201D; (2011)

Testing of high-speed Digital-to-Analog Converters (DACs) is a challenging task, as it requires large number of high-speed synchronized input signals with specific test patterns. To overcome this problem, we propose use of PRBS signals with an “Alternate-Bit-Tapping” technique and eye-diagram measurement as a solution to efficiently generate the test-vectors and test the DACs. This approach covers all levels and transitions necessary for testing the dynamic behavior of the DAC completely, in minimum possible time. Circuit level simulations are used to verify its usefulness in testing a 4-bit 20-GS/s current-steering DAC.
Helicobacter pylori cagA and vacA genes in dyspeptic Ghanaian patients (2017)

Majority of biopsies were colonized with H. pylori harboring both cagA and vacA. H. pylori cagA-(internal duplication region) was more prevalent than cagA-(hydrophilic region). Duodenal ulcer was more likely than other diagnoses to have detectable cagA-(hydrophilic region) or vacAs1m1.