gebhart/patrepeval huggingface dataset:
Chemical and Structural Configuration of Pt-Doped Metal Oxide Thin Films Prepared by Atomic Layer Deposition (2019)

Pt-doped semiconducting metal oxides and Pt metal clusters embedded in an oxide matrix are of interest for applications such as catalysis and gas sensing, energy storage, and memory devices. Accurate tuning of the dopant level is crucial for adjusting the properties of these materials. Here, a novel atomic layer deposition (ALD)-based method for doping Pt into In2O3 specifically, and metals in metal oxides in general, is demonstrated. This approach combines alternating exposures of Pt and In2O3 ALD processes in a single “supercycle” followed by supercycle repetition leading to multilayered nanocomposites. The atomic-level control of ALD and its conformal nature make the method suitable for accurate dopant control even on high-surface-area supports. The oxidation state, local structural environment, and crystalline phase of the embedded Pt dopants were obtained by means of X-ray characterization methods and high-angle annular dark-field scanning transmission electron microscopy. In addition, this approach allows characterization of the nucleation stages of metal ALD processes by stacking those states multiple times in an oxide matrix. Regardless of experimental conditions, a few Pt ALD cycles lead to the formation of oxidized Pt species due to their highly dispersed nature, as proven by X-ray absorption spectroscopy. Grazing-incidence small-angle X-ray scattering and high-resolution scanning transmission electron microscopy, combined with energy-dispersive X-ray spectroscopy, show that Pt is evenly distributed in the In2O3 matrix without the formation of clusters. For a larger number of Pt ALD cycles, typically >10, the oxidation state gradually evolves toward fully metallic, and metallic Pt clusters are obtained within the In2O3 matrix. This work reveals how tuning of the ALD supercycle approach for Pt doping allows controlled engineering of the Pt compositional and structural configurations within a metal oxide matrix.
Acidianus infernus gen. nov., sp. nov., and Acidianus brierleyi Comb. nov.: Facultatively Aerobic, Extremely Acidophilic Thermophilic Sulfur-Metabolizing Archaebacteria (1986)

A new genus, Acidianus, is characterized from studies of 26 isolates of thermoacidophilic archaebacteria from different solfatara fields and marine hydrothermal systems; these isolates grow as facultative aerobes by lithotrophic oxidation and reduction of SO, respectively, and are therefore different from the strictly aerobic Sulfolobus species. The Acidianus isolates have a deoxyribonucleic acid guanine-plus-cytosine content of 31 mol%. In contrast, two of three Sulfolobus species, including the type species, have a guanine-plus-cytosine content of 37 mol%; Sulfolobus brierleyi is the exception, with a guanine-plus-cytosine content of 31 mol%. In contrast to its earlier descriptions, S. brierleyi is able to grow strictly anaerobically by hydrogen-sulfur autotrophy. Therefore, it is described here as a member of the genus Acidianus. The following species are assigned to the genus Acidianus: Acidianus infernus sp. nov. (type strain, strain DSM 3191) and Acidianus brierleyi comb. nov. (type strain, strain DSM 1651).
Proceedings of the KG-BIAS Workshop 2020 at AKBC 2020 (2020)

The KG-BIAS 2020 workshop touches on biases and how they surface in knowledge graphs (KGs), biases in the source data that is used to create KGs, methods for measuring or remediating bias in KGs, but also identifying other biases such as how and which languages are represented in automatically constructed KGs or how personal KGs might incur inherent biases. The goal of this workshop is to uncover how various types of biases are introduced into KGs, investigate how to measure, and propose methods to remediate them.
Effects of Added Egg White or Whey Protein Concentrate on Thermal Transitions in Rigidity of Croaker Surimi (1985)

ABSTRACT Rigidities of surimi [refined minced fish (MF)] sols, alone and in combination with egg white (EW) and whey protein concentrate (WPC) were measured during constant‐rate heating by a nondestructive technique. Each of the protein types tested showed measureable changes due to variation of the heating rate or NaCl concentration of the sol. Rigidity and differential scanning calorimetric (DSC) thermograms for mixtures resembled composites of the individual protein source profiles, indicating that no major changes occurred in thermal gelling properties of the component proteins due to mixing. Maximum rigidity values indicated more favorable gelation of MF/WPC than MF/EW combinations.
Toll-like receptor 4 and MAIR-II/CLM-4/LMIR2 immunoreceptor regulate VLA-4-mediated inflammatory monocyte migration (2014)

Inflammatory monocytes play an important role in host defense against infections. However, the regulatory mechanisms of transmigration into infected tissue are not yet completely understood. Here we show that mice deficient in MAIR-II (also called CLM-4 or LMIR2) are more susceptible to caecal ligation and puncture (CLP)-induced peritonitis than wild-type (WT) mice. Adoptive transfer of inflammatory monocytes from WT mice, but not from MAIR-II, TLR4 or MyD88-deficient mice, significantly improves survival of MAIR-II-deficient mice after CLP. Migration of inflammatory monocytes into the peritoneal cavity after CLP, which is dependent on VLA-4, is impaired in above mutant and FcRγ chain-deficient mice. Lipopolysaccharide stimulation induces association of MAIR-II with FcRγ chain and Syk, leading to enhancement of VLA-4-mediated adhesion to VCAM-1. These results indicate that activation of MAIR-II/FcRγ chain by TLR4/MyD88-mediated signalling is essential for the transmigration of inflammatory monocytes from the blood to sites of infection mediated by VLA-4.
A BPNN based two-step image super-resolution reconstruction method (2010)

This paper first proposes a simple and effective nonuniform interpolation method and a deblurring method based on back propagation neural networks (BPNN). The proposed non-uniform interpolation method and deblurring method are then coupled to constitute a novel two-step super-resolution algorithm. The simulated results indicate that the proposed two-step super-resolution method shows better results than classic two-step super-resolution method. Because the nonuniform interpolation method is added before the proposed BPNN based deblurring method is performed, the BPNN is expanded to be used in uncontrolled microscanning which has non-uniform shifts between frames.
Reciprocal Translocation Observed in End-of-Production Cells of a Commercial CHO-Based Process. (2018)

The expression of recombinant therapeutic proteins in mammalian cells depends on the establishment of a cell line with the gene of interest integrated in the host genome and stably expressed over time. Before being used for commercial production, cell lines are submitted to a qualification program in order to ensure their phenotypic and genotypic characteristics and the efficacy and safety of the product. During the production life cycle of a therapeutic protein, additional cells banks have to be validated after exhaustion of the current qualified cell bank in order to support the commercial production continuum of the recombinant protein. It is during the validation of an additional working cell bank derived from a validated master cell bank that we detected a different chromosome bearing the gene of interest in a portion of cells at the end of the upstream production phase. In our case, this event did not affect the process performance, the product quality, or its safety profile, but it highlights the need to characterize the integrity of the gene of interest in end-of-production cells when producing recombinant proteins for human use.
Influence of Material Moisture during Laser Joining of Polyamide 6.6 to Aluminum (2017)

peer reviewed
Co-morbidity in Gaucher's disease results of a nationwide enquiry in Spain. (2000)

As a group, Gaucher's patients seem to have a greater risk of suffering other common unrelated diseases than carriers or healthy relatives. This excess of risk is particularly higher among female patients and can not be explained in terms of differences in age. Carrier status doesn't seem to highten the risk of suffering other diseases.
Performance Comparison of Distance Protection Schemes for Shunt-FACTS Compensated Transmission Lines (2007)

This paper presents a comparative study of the performance of distance relays for transmission lines compensated by shunt connected flexible ac transmission system (FACTS) controllers/devices. The objective of this study is to evaluate the performance of various distance protection schemes on transmission lines with shunt-FACTS devices applied for midpoint voltage control. The impact of two types of shunt FACTS devices, static var compensator (SVC) and static synchronous compensator (STATCOM) on the transmission line distance protection schemes is studied for different fault types, fault locations and system conditions. The power system elements and the shunt-FACTS devices with their associated controllers are modeled using RSCAD/RTDS software. The results are based on the performance of commercial distance relays using a real time digital simulator (RTDS).
Telehealth: A new paradigm? Paediatric surgical subspecialty telemedicine survey in the COVID-19 Pandemic at a tertiary care centre (2022)

Background: Although the technology has been available and several pilot studies have shown success, use of telemedicine has previously been limited in the United States, especially among surgeons. This study aimed to investigate the benefits and obstacles for successful implementation of telemedicine visits in paediatric surgical subspecialties amid the COVID-19 pandemic. Methods: We analysed survey data from telemedicine visits with paediatric surgical subspecialists from May 1 through June 30, 2020 at our paediatric surgery subspecialty clinics. Univariate logistic regression was used to determine associations in survey responses and various demographic factors. Results: There were 164 respondents to the survey. The most frequently cited barrier to care was ability to get time off work (46.3%). Overall satisfaction with the telemedicine visit was 93.8%, and 55.6% responded that they would choose video telemedicine rather than an in-person or telephone visit. Those living at least 25 miles from the hospital had increased odds of indicating interest in using telemedicine for future visits (OR = 2.56, 95% CI = 1.12–5.86, p = 0.026). The average respondent saved between 30 minutes and 1 hour, and 45 minutes using telemedicine. Conclusions: The implementation of telemedicine at our institution in the paediatric surgical subspecialties has proven to be effective and well-received. Given the benefits of time and money saved for families, paired with high satisfaction rates and continued interest, paediatric surgical subspecialists should work to incorporate virtual visits into regular patient care, even well after the COVID-19 pandemic. Level of Evidence: Level IV
Nanorods versus Nanovesicles from Amphiphilic Dendrofullerenes (2011)

Three new amphiphilic dendrofullerenes endowed with 4, 8, and 16 carboxylic groups have been efficiently prepared by using a click chemistry methodology. These amphiphilic fullerene derivatives aggregate forming micelles, nanorods, or hollow vesicles depending on the concentration and on the solid substrate.
The linear zero-forcing crosstalk canceler is near-optimal in DSL channels (2005)

Crosstalk is a serious problem in next-generation DSL systems, such as VDSL. Several non-linear crosstalk cancelers and pre-compensators have been proposed to address this. Unfortunately, they all suffer from high complexity, DFE error propagation and/or require modification of CPE. We propose the use of a simple linear zero-forcing crosstalk canceler in upstream transmission and a simple linear diagonalizing crosstalk precoder in downstream transmission. Certain properties of DSL channels ensure that these simple linear designs lead to near-optimal performance. We formulate a bound on the performance of these schemes and show that in 99% of upstream DSL channels, the linear zero-forcing canceler achieves 97% of the theoretical channel capacity. Similarly, in 99% of downstream DSL channels, the linear diagonalizing precoder achieves 91% of the theoretical channel capacity.
A Comprehensive Model of Temperature Behavior in a Horizontal Well (2005)

Abstract Use of distributed temperature sensors is becoming increasingly common for monitoring producing sections of horizontal wells through a real-time measurement of a temperature profile. This information can potentially be inverted to infer the types and amounts of fluid entering along the wellbore. This information is essential for reservoir management to identify excessive water or gas influx, to guide the action of sliding sleeves or other downhole flow control devices, and to decide if reservoir stimulation is needed in a particular horizontal section. The inferences described above require a model to translate temperature information into flow information. This paper presents a model for predicting the temperature profile in a nominally horizontal well during normal production (steady-state flow). A forward model of the temperature profile caused by given flow conditions can be the basis of the inverse model needed to determine flow profiles Prediction of the wellbore temperature profile requires models of all of the often-subtle thermal effects occurring in the reservoir and in the wellbore itself. For the reservoir temperature model, we couple mass and energy balances of fluid flow in a permeable media in a box-shaped homogeneous reservoir with a wellbore temperature model using a multisegment technique. Similarly for the wellbore, we couple mass, momentum, and energy balances to model pressure and temperature behavior. The models presented in this paper account for Joule-Thomson effects, and convective and conductive heat transfer. The primary results of the model are estimates of the extent of temperature change from geothermal temperature during flow. Results show that temperature changes of a few degrees are possible; temperature changes of this magnitude are certainly detectable with current technology. A second result is a demonstration of the inference of single phase and multiphase flow profiles from a synthetic case. Sensitivity studies with the model illustrate the flow conditions that cause measurable temperature changes or anomalies that could be recognized in an analysis of distributed temperature measurements.
Multibandwidth Kernel-Based Object Tracking (2010)

Object tracking using Mean Shift (MS) has been attracting considerable attention recently. In this paper, we try to deal with one of its shortcoming. Mean shift is designed to find local maxima for tracking objects. Therefore, in large target movement between two consecutive frames, the local and global modes are not the same as previous frames so that Mean Shift tracker may fail in tracking the desired object via localizing the global mode. To overcome this problem, a multibandwidth procedure is proposed to help conventional MS tracker reach the global mode of the density function using any staring points. This gradually smoothening procedure is called Multi Bandwidth Mean Shift (MBMS) which in fact smoothens the Kernel Function through a multiple kernel-based sampling procedure automatically. Since it is important for us to have less computational complexity for real-time applications, we try to decrease the number of iterations to reach the global mode. Based on our results, this proposed version of MS enables us to track an object with the same initial point much faster than conventional MS tracker.
MicroRNA-1246 expression associated with CCNG2-mediated chemoresistance and stemness in pancreatic cancer (2014)

miR-1246 expression was associated with chemoresistance and CSC-like properties via CCNG2, and could predict worse prognosis in pancreatic cancer patients.
Phosphatases modified by LH signaling in ovarian follicles: testing their role in regulating the NPR2 guanylyl cyclase (2023)

Quantitative mass spectrometric analysis of phosphatases whose phosphorylation state is rapidly modified by luteinizing hormone provides clues about how LH signaling dephosphorylates NPR2 as well as a resource for future studies.
Electrophysiology, agent-based modeling and inverse optimal control applications in neuroethology (2012)

Decision-making is based on the integration of sensory information, motiva-tional states and memory, from which assessment of outcomes and optimal action selection emerge. In foraging, animals tend to make decisions that reconcile two core goals: energy maximization and time minimization. The predatory sea-slug Pleurobranchaea californica has a simple, accessible ner-vous system and exhibits a repertory of simple behavioral elements that constitute effective foraging strategies. In this thesis, we introduce initial findings of sensory neurons identified through intracellular staining and elec-trophysiology, potentially linked to central sensory processing in the Pleuro-branchaea. To further expand the principles underlying sensory integration and behavioral selection, we implemented a multi-agent based NetLogo simu-lation to model autonomous decision-making in the predatory sea-slug Pleu-robranchaea. In particular, the model incorporated cost-benefit decisions in foraging by integrating sensation, internal state and learning in the virtual agent, replicating the particular behavioral selection process of the Pleuro-branchaea. Finally, we propose two Markov decision processes to model how the animal makes decisions in its environment. Given the observed behaviors, we utilize inverse optimal control to succinctly characterize a class of utility functions the animal is maximizing. This research methodology combines principles from neurophysiology, agent-based modeling, classical condition-ing, Bayesian statistics and control theory to investigate foraging decisions of the Pleurobranchaea, as it integrates sensation, internal state and learning mechanisms. ii “Where ignorance lurks, so too do the frontiers of discovery and imagination.” — Neil deGrasse Tyson iii
Simulation of size-dependent aerosol deposition in a realistic model of the upper human airways (2017)

An Eulerian internally mixed aerosol model is used for predictions of deposition inside a realistic cast of the human upper airways. The model, formulated in the multi-species and compressible framework, is solved using the sectional discretization of the droplet size distribution function to accurately capture size-dependent aerosol dynamics such as droplet drift, gravitational settling and diffusion. These three mechanisms are implemented in a consistent way in the model, guaranteeing that the total droplet mass as given by the droplet size distribution is always equal to the total droplet mass due to the mass concentration fields. To validate the model, we simulate monodisperse glycerol aerosol deposition inside the lung cast, for which experimental data is available. Provided that an adequate computational mesh is used and an adequate boundary treatment for the inertial deposition velocity, excellent agreement is found with the experimental data. Finally, we study the size-dependent deposition inside the lung cast for a polydisperse aerosol with droplet sizes ranging from the nanometer scale to beyond the micrometer scale. The typical ‘V-shape’ deposition curve is recovered. The aim of this paper is to 1) provide an overview of the Eulerian aerosol dynamics model and method, to 2) validate this method in a relevant complex lung geometry and to 3) explore the capabilities of the method by simulating polydisperse aerosol deposition.
Hexagonal BaTiO(3–x)HxOxyhydride as a Water-Durable Catalyst Support for Chemoselective Hydrogenation (2022)

We present heavily H<sup>-</sup>-doped BaTiO<sub>(3-<i>x</i>)</sub>H<sub><i>x</i></sub> (<i>x</i> ≈ 1) as an efficient and water-durable catalyst support for Pd nanoparticles applicable to liquid-phase hydrogenation reactions. The BaTiO<sub>(3-<i>x</i>)</sub>H<sub><i>x</i></sub> oxyhydride with a hexagonal crystal structure (<i>P</i>6<sub>3</sub>/<i>mmc</i>) was synthesized by the direct reaction of BaH<sub>2</sub> and TiO<sub>2</sub> at 800 °C under a stream of hydrogen, and the estimated chemical composition was BaTiO<sub>2.01</sub>H<sub>0.96</sub>. Density functional theory calculations and magnetic measurements indicated that such heavy H<sup>-</sup> doping results in a metallic nature with delocalized electrons and a low work function. The potential of BaTiO<sub>(3-<i>x</i>)</sub>H<sub><i>x</i></sub> as a catalyst support was examined for the selective hydrogenation of unsaturated C-C bonds by Pd nanoparticles deposited on BaTiO<sub>(3-<i>x</i>)</sub>H<sub><i>x</i></sub>. We found that the turnover frequency for phenylacetylene hydrogenation per total amount of Pd in Pd/BaTiO<sub>(3-<i>x</i>)</sub>H<sub><i>x</i></sub> was the highest among the supported Pd catalysts reported to date. The strong electronic charge transfer between Pd and the support, as confirmed by X-ray photoelectron spectroscopy measurements, can be attributed to be responsible for such high catalytic activity. The combination of the BaTiO<sub>(3-<i>x</i>)</sub>H<sub><i>x</i></sub> support and Pd nanoparticles provides for the selective hydrogenation of unsaturated C-C bonds and highlights the validity of catalyst design that integrates H<sup>-</sup> in support materials.
Online Meta-Learning (2019)

A central capability of intelligent systems is the ability to continuously build upon previous experiences to speed up and enhance learning of new tasks. Two distinct research paradigms have studied this question. Meta-learning views this problem as learning a prior over model parameters that is amenable for fast adaptation on a new task, but typically assumes the set of tasks are available together as a batch. In contrast, online (regret based) learning considers a sequential setting in which problems are revealed one after the other, but conventionally train only a single model without any task-specific adaptation. This work introduces an online meta-learning setting, which merges ideas from both the aforementioned paradigms to better capture the spirit and practice of continual lifelong learning. We propose the follow the meta leader algorithm which extends the MAML algorithm to this setting. Theoretically, this work provides an $\mathcal{O}(\log T)$ regret guarantee with only one additional higher order smoothness assumption in comparison to the standard online setting. Our experimental evaluation on three different large-scale tasks suggest that the proposed algorithm significantly outperforms alternatives based on traditional online learning approaches.
Eplerenone as a novel treatment for persistent subretinal fluid following retinal detachment surgery (2018)

To our knowledge, this is the first report of its kind to show the effectivity of oral eplerenone treatment in the reduction of SRF following retinal detachment surgery.