gebhart/patrepeval huggingface dataset:
Primary Lymphedema: Clinical Features and Management in 138 Pediatric Patients (2011)

Pediatric primary lymphedema usually involves the lower extremities. Boys typically are affected at birth, and girls most often present during adolescence. Most patients do not have major morbidity, are successfully managed by compression, and do not require surgical treatment.
Repository drugs. VI. 4'-[N-(Aralkylidene-, -benzylidene-, and-naphthylidene)sulfanilyl]anilides, 4'-[N-[(dimethylamino)methylene]sulfanilyl]anilides, and related sulfanilylanilides with prolonged antimalarial and antileprotic action (1969)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRepository drugs. VI. 4'-[N-(Aralkylidene-, -benzylidene-, and-naphthylidene)sulfanilyl]anilides, 4'-[N-[(dimethylamino)methylene]sulfanilyl]anilides, and related sulfanilylanilides with prolonged antimalarial and antileprotic actionDonald F. Worth, Edward F. Elslager, and Annette A. PhillipsCite this: J. Med. Chem. 1969, 12, 4, 591–596Publication Date (Print):July 1, 1969Publication History Published online1 May 2002Published inissue 1 July 1969https://pubs.acs.org/doi/10.1021/jm00304a007https://doi.org/10.1021/jm00304a007research-articleACS PublicationsRequest reuse permissionsArticle Views61Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Biophysical properties of the human cardiac gap junction channel. (1993)

1. Gap junction channels interconnect cells of the pacemaking, conduction and contraction elements of the heart and also endothelial and smooth muscle cells of vasculature, thereby providing pathways for electrotonic current spread and for second messenger diffusion. The major gap junction protein in the cardiovascular system is connexin43. 2. When human connexin43 is stably expressed in pairs of a communication-deficient cell line (SKHep1) channels are produced with unitary conductance (gamma j), lipophile sensitivity and voltage-dependent gating similar to those of mammalian systems in which connexin43 is endogenously expressed. 3. At moderate transjunctional voltages (Vj), two gamma j values dominated the recordings, about 60 and 90 pS with CsCl patch solution. The smaller channel size is favored by phosphorylating treatments and the larger channel, by dephosphorylating treatments. 4. Human connexin43 mutants truncated at the carboxy termini display a change in gamma j while a point mutation in the third transmembrane spanning domain appears to change channel selectivity. 5. Voltage dependence of the human connexin43 channel is marked at Vjs, above +/- 50 mV, but large residual conductance remains (due probably to a voltage-insensitive substate) even at the largest Vj values; kinetic but not steady-state behavior is affected by phosphorylation state.
Calcium Carbonate Biofouling (2019)

Abstract Biofouling is the formation of composite deposits consisting of living organic matter and inorganic salts. So far there is little mechanistic information on biofouling. In this work, the role of the presence of microalgae on the nucleation and growth of calcium carbonate from aqueous supersaturated solutions was investigated with free drift and constant supersaturation batch experiments, at 25°C. Living and dead microalgae colonies were used to inoculate aqueous solutions supersaturated with respect to calcium carbonate. The presence of algae accelerated the crystal growth of calcium carbonate while at the same time affected the nucleation process showing catalytic activity. Higher acceleration was found for higher microalgae populations. The extracellular components of the test microalgae are believed to play an important role on the nucleation and the subsequent rate of precipitation of calcite, which was the only polymorph found to grow on algae substrates. It is suggested that the polysaccharides present, exert a templating effect for the formation of the mineral phase on the organic matter.
Full Genomic Characterization of a Saffold Virus Isolated in Peru (2015)

While studying respiratory infections of unknown etiology we detected Saffold virus in an oropharyngeal swab collected from a two-year-old female suffering from diarrhea and respiratory illness. The full viral genome recovered by deep sequencing showed 98% identity to a previously described Saffold strain isolated in Japan. Phylogenetic analysis confirmed the Peruvian Saffold strain belongs to genotype 3 and is most closely related to strains that have circulated in Asia. This is the first documented case report of Saffold virus in Peru and the only complete genomic characterization of a Saffold-3 isolate from the Americas.
HIGH RESOLUTION, CW LASER INDUCED CHARGE TRANSFER STUDY OF $CO^{+}$ AND $N^{+}_{2}$ (1986)

$^{1}$ T. A. Miller, T. Sizuki and E. Hirota, J. Chem. Phys. 80, 4671 (1984). $^{2}$ R. D. Brown R. G. Dittman, and D. C. McGilvery. J. Mol. Spectosc. 104, 337 (1984). Address of C.-H. Kuo: Department of Chemistry, University of California, Santa Barbara, California 93106. Address of I. Milkman, Y. Al-Ramadin and J.T. Moseley: Department of Physics, University of Oregon, Eugene, Oregon, 97403. Address of T.C. Steimle: Department of Chemistry, Arizona State Univeristy. Tempe, Arizona, 85287.
Reactions involving fluoride ion. Part 35. Fluorinated derivatives of benzyl anions (1991)

Hexafluoroisopropyl groups were introduced into fluorinated aromatic systems using 2H-pentafluoropropene and caesium fluoride. Reaction with pentafluoronitrobenzene gave a fluorinated isoxazole and a mechanism is advanced for this reaction. Direct observation of fluorinated benzyl anion derivatives has been possible and effects on fluorine chemical shifts are discussed.
Rho/Rho kinase signaling mediates increased basal pulmonary vascular tone in chronically hypoxic rats (2004)

Recent evidence suggests that Rho/Rho kinase signaling plays an important role in the sustained vasoconstriction induced by many agonists and is involved in the pathogenesis of systemic vascular diseases. However, little is known about its role in increased vascular tone in hypoxic pulmonary hypertension (PH). The purpose of this study was to examine whether Rho/Rho kinase-mediated Ca2+ sensitization contributed to sustained vasoconstriction and increased vasoreactivity in hypoxic PH in rats. Acute intravenous administration of Y-27632, a Rho kinase inhibitor, nearly normalized the high pulmonary arterial blood pressure and total pulmonary resistance in chronically hypoxic rats. In contrast to nifedipine, Y-27632 also markedly decreased elevated basal vascular tone in hypertensive blood-perfused lungs and isolated pulmonary arteries. Y-27632 and another Rho kinase inhibitor, HA-1077, completely reversed nitro-L-arginine-induced vasoconstriction in physiological salt solution-perfused hypertensive lungs, whereas inhibitors of myosin light chain kinase (ML-9), protein kinase C (GF-109203X), phosphatidylinositol 3-kinase (LY-294002), and tyrosine kinase (tyrphostin A23) caused only partial or no reversal of the vasoconstriction. Vasoconstrictor responses to KCl were augmented in hypertensive physiological salt solution-perfused lungs and pulmonary arteries, and the augmentation was eliminated by Y-27632. These results suggest that Rho/Rho kinase-mediated Ca2+ sensitization plays a central role in mediating sustained vasoconstriction and increased vasoreactivity in hypoxic PH.
Microhollow cathode discharges (1996)

The current–voltage characteristics of hollow cathode discharges and their predischarges in argon under dc and pulsed conditions were found to have a positive slope at pressures up to approximately 50 Torr, and currents up to 20 mA, at a hole diameter of 0.7 mm. In this range of pressure and current, parallel operation of hollow cathode discharges, without ballast, was demonstrated. Scaling to higher pressure is possible by reducing the hole diameter. Pulsed experiments with an array of cathode rings of 75 μm diameter allowed us to obtain parallel operation of more than 50 discharges at a pressure of 350 Torr in air.
ChemInform Abstract: N‐BUTYLLITHIUM BEI DER AMINOLYSE UND AMMONOLYSE VON ESTERN (1970)

Abstract Tetrahydrochinolin (Ia) kann über das mit NaH hergestellte Salz (Ib) mit dem Dicarbonsäureester (II) in das Halbamid (III) übergeführt werden.
Implementing Recommendation Algorithms in a Large-Scale Biomedical Science Knowledge Base (2017)

The number of biomedical research articles published has doubled in the past 20 years. Search engine based systems naturally center around searching, but researchers may not have a clear goal in mind, or the goal may be expressed in a query that a literature search engine cannot easily answer, such as identifying the most prominent authors in a given field of research. The discovery process can be improved by providing researchers with recommendations for relevant papers or for researchers who are dealing with related bodies of work. In this paper we describe several recommendation algorithms that were implemented in the Meta platform. The Meta platform contains over 27 million articles and continues to grow daily. It provides an online map of science that organizes, in real time, all published biomedical research. The ultimate goal is to make it quicker and easier for researchers to: filter through scientific papers; find the most important work and, keep up with emerging research results. Meta generates and maintains a semantic knowledge network consisting of these core entities: authors, papers, journals, institutions, and concepts. We implemented several recommendation algorithms and evaluated their efficiency in this large-scale biomedical knowledge base. We selected recommendation algorithms that could take advantage of the unique environment of the Meta platform such as those that make use of diverse datasets such as a citation networks, text content, semantic tag content, and co-authorship information and those that can scale to very large datasets. In this paper, we describe the recommendation algorithms that were implemented and report on their relative efficiency and the challenges associated with developing and deploying a production recommendation engine system.
Hunting Bubbles Falkor Cruise 2019 (2019)

The Hunting Bubbles Cruise took place in August-September 2018 on the R/V Falkor (cruise ID 180824). Ship time was provided by the Schmidt Ocean Institute. This cruise investigated transport of methane from seeps located on the Cascadia Margin. Data archived at the WHOAS repository supplements additional data from this cruise available at the R2R rolling deck to repository and at MGDS: Marine Geoscience Data System.
Dynamic Partitioning Supporting Load Balancing for Distributed RDF Graph Stores (2019)

Various resource description framework (RDF) partitioning methods have been studied for the efficient distributed processing of a large RDF graph. The RDF graph has symmetrical characteristics because subject and object can be used interchangeably if predicate is changed. This paper proposes a dynamic partitioning method of RDF graphs to support load balancing in distributed environments where data insertion and change continue to occur. The proposed method generates clusters and subclusters by considering the usage frequency of the RDF graph that are used by queries as the criteria to perform graph partitioning. It creates a cluster by grouping RDF subgraphs with higher usage frequency while creating a subcluster with lower usage frequency. These clusters and subclusters conduct load balancing by using the mean frequency of queries for the distributed server and conduct graph data partitioning by considering the size of the data stored in each distributed server. It also minimizes the number of edge-cuts connected to clusters and subclusters to minimize communication costs between servers. This solves the problem of data concentration to specific servers due to ongoing data changes and additions and allows efficient load balancing among servers. The performance results show that the proposed method significantly outperforms the existing partitioning methods in terms of query performance time in a distributed server.
Optical flow estimation and moving object segmentation based on median radial basis function network (1998)

Various approaches have been proposed for simultaneous optical flow estimation and segmentation in image sequences. In this study, the moving scene is decomposed into different regions with respect to their motion, by means of a pattern recognition scheme. The inputs of the proposed scheme are the feature vectors representing still image and motion information. Each class corresponds to a moving object. The classifier employed is the median radial basis function (MRBF) neural network. An error criterion function derived from the probability estimation theory and expressed as a function of the moving scene model is used as the cost function. Each basis function is activated by a certain image region. Marginal median and median of the absolute deviations from the median (MAD) estimators are employed for estimating the basis function parameters. The image regions associated with the basis functions are merged by the output units in order to identify moving objects.
A Zero‐Emission Fuel Cell that uses Carbonaceous Colloids from Biomass Waste as Fuel Source (2009)

Carbonaceous microspheres dispersed in water are produced from biomass waste by hydrothermal carbonization and used as fuel in an indirect carbon fuel cell (ICFC). Thus, a chemical pathway to an environment-friendly energy storage medium with zero emission balance regarding greenhouse gases is presented. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
A 4&#x00D7; 25-to-28Gb/s 4.9mW/Gb/s &#x2212;9.7dBm high-sensitivity optical receiver based on 65nm CMOS for board-to-board interconnects (2013)

Growing data traffic requires low-power 25Gb/s-class optical interconnects for board-to-board transmission inside ICT systems [1-4]. The main power consumption of an optical link strongly depends on the sensitivity of the TIA; thus, development of a high-sensitivity TIA is a key to creating a low-power optical link., There are two challenges concerning the design of such a TIA: (1) improving the sensitivity of TIA without sacrificing bandwidth and (2) suppressing ISI due to insertion loss. To address these two issues, a 4×25Gb/s CMOS optical receiver (RX), which includes a four-channel TIA and a PD array operating at 1.3μm wavelength, is developed. The key components of the TIA are an automatic-decision-threshold control (ATC) with an offset canceller and low-voltage output driver (Drv) with peaking value of 7.7dB at 12.5GHz, achieved by separating equalizer (EQ) function and output buffer (BUF). The TIA attains a sensitivity of -9.7dBm (86μApp) optical modulation amplitude (OMA) and an eye opening of 65% at 25Gb/s. Operation at 28Gb/s with sensitivity of -8.2dBm (121μApp) OMA is also confirmed.
Easy Access to Esters with a Benzylic Quaternary Carbon Center from Diallyl Malonates by Palladium-Catalyzed Decarboxylative Allylation (2007)

Diallyl 2-alkyl-2-arylmalonates underwent palladium-catalyzed decarboxylative allylation quickly under mild conditions. In contrast, no reaction took place with diallyl 2,2-dialkylmalonates under the same conditions. Electron-donating phosphine ligands were found to be vital for this reaction. Most of the solvents used did not affect the catalytic cycle. Catalysis in [bmim][BF4], a well-known ionic liquid, was inhibited as a result of formation of a hydrogen bond between a carboxylate anion and a [bmim]+ cation; however, the reaction in [bdmim][BF4], in which the acidic proton of [bmim][BF4] was replaced with a methyl group, proceeded smoothly. The catalytic mechanism was investigated using a tetradeuterated substrate and an enzymatically synthesized enantio-enriched allyl methyl 2-methyl-2-phenylmalonate. Even the electron-deficient phosphite ligand was found to be active for catalysis of diallyl 2-methyl-2-(2- or 4-nitrophenyl)malonates.
Classification of background noises for hearing-aid applications (1995)

A background-noise classification procedure is being developed for hearing-aid applications, wherein the hearing-aid response would be adjusted in response to changes in the noise environment. The classification procedure is based on measuring four signal features giving the fluctuations of the signal envelope and the mean frequency and low- and high-frequency slopes of the average spectrum. A more complicated procedure, based on determining the envelope modulation spectra in auditory critical bands, was also investigated and was found to offer no advantages over the simpler procedure. The accuracy of the classification procedure was determined for eleven everyday background noises under optimal conditions where the training and test noise sequences were different portions of the same short noise recording. A cluster analysis was used to determine the similarities among the feature vectors for the noises, and when the noises are grouped into a reduced number of clusters the noise-classification accuracy using the four features exceeds 90%.
How far should nutrition reach? (2006)

The table shows that Spain had the best average life expectancy over the 35 years, and Australia now has a longer life expectancy than any Mediterranean country. The countries that started with long life expectancies have seen a lengthening of about 12% in 35 years; while countries with lower life expectancies have had much bigger gains, around 40% in the period.
Genome reprogramming during sporulation (2009)

When environmental conditions compromise survival, single celled organisms, such as the budding yeast S. cerevisiae, induce and complete a differentiation program called sporulation. The first step consists of meiosis, which generates genetic diversity within the eventual haploid cells. The post-meiotic maturation stage reinforces protective barriers, such as the spore wall, against deleterious external conditions. In later stages of sporulation, the spore nucleus becomes highly compacted, likely sharing certain characteristics with the metazoan male gamete, the spermatozoon. The sporulation differentiation program involves many chromatin-related events, including execution of a precise transcription program involving more than one thousand genes. Here, we review how chromatin structure and genome reprogramming regulate the sporulation transcription program, and how post-meiotic events reorganize spore chromatin.
Recent Heliotron E Physics Study Activities and Engineering Developments (1990)

Recent studies of transport, magnetohydrodynamic stability, and divertor action on Heliotron E are summarized. A pellet injector and a new diagnostic system are developed. Moreover, the Heliotron group is conducting research and development on heating and other new systems for the Large Helical Device.
Perioperative outcomes among patients with end-stage renal disease following coronary artery bypass surgery in the USA (2010)

Since 1988, an increasing number of patients with ESRD have been receiving CABG in the USA. Despite increasing co-morbidities, operative mortality rates and length of in-hospital stay have declined substantially. Nonetheless, mortality rates remain almost 3-fold higher compared to non-ESRD patients indicating a need for ongoing improvement.
Role of the Axial Length/Corneal Radius Ratio in Determining the Refractive State of the Eye (1994)

The purpose of our study was to investigate the extent to which the ratio between axial length and corneal radius (the AL/CR ratio) determines the refractive state of the human eye. Subjects for the study were 194 young adults between the ages of 18 and 30 years, whose spherical equivalent refraction ranged from +7.91 to -13.32 D. For each subject, manifest objective refraction, corneal radii, and axial ocular distances were measured. Lens power was determined using a formula proposed by Bennett and Rabbetts. The AL/CR ratio was found to be approximately 3.00 for emmetropic eyes, ranging from 2.60 for the most highly hyperopic eye to 4.10 for the most highly myopic eye. The coefficient of determination of linear regression for the AL/CR ratio as a function of spherical equivalent refraction was 0.84, suggesting that 84% of the variance in refraction could be accounted for by variance of the AL/CR ratio. The results of the study suggest that for a given amount of ametropia, an eye having a relatively high AL/CR ratio would tend to have a low-powered lens (indicating that the lens had "emmetropized"), whereas an eye having a relatively low AL/CR ratio would tend to have a high-powered lens. We conclude that the AL/CR ratio can provide information concerning the extent to which the lens has emmetropized by reducing its power concurrent with axial elongation.
Detecting Burnscar from Hyperspectral Imagery via Sparse Representation with Low-Rank Interference (2016)

In this paper, we propose a burnscar detection model for hyperspectral imaging (HSI) data. The proposed model contains two-processing steps in which the first step separate and then suppress the cloud information presenting in the data set using an RPCA algorithm and the second step detect the burnscar area in the low-rank component output of the first step. Experiments are conducted on the public MODIS dataset available at NASA official website.
Thermopower in Transition from Tunneling to Hopping (2022)

The Seebeck effect of a molecular junction in a hopping regime or tunneling-to-hopping transition remains uncertain. This paper describes the Seebeck effect in molecular epitaxy films (OPI<sub><i>n</i></sub> where <i>n</i> = 1-9) based on imine condensation between an aryl amine and aldehyde and investigates how the Seebeck coefficient (<i>S</i>, μV/K) varies at the crossover region. The <i>S</i> value of OPI<sub><i>n</i></sub> linearly increased with increasing the molecular length (<i>d</i>, nm), ranging from 7.2 to 38.0 μV/K. The increasing rate changed from 0.99 to 0.38 μV·K<sup>-1</sup> Å<sup>-1</sup> at <i>d</i> = 3.4 nm (OPI<sub>4</sub>). Combined experimental and theoretical studies indicated that such a change stems from a tunneling-to-hopping transition, and the small but detectable length-dependence of thermopower in the long molecules originates from the gradual reduction of the tunneling contribution to the broadening of molecular orbital energy level, rather than its relative position to the Fermi level. Our work helps to bridge the gap between bulk and nanoscale thermoelectric systems.