gebhart/patrepeval huggingface dataset:
Branching fraction measurements of chargedBdecays toK*+K+K−,K*+π+K−,K*+K+π−andK*+π+π−final states (2006)

Branching fraction and asymmetry measurements of charmless ${B}^{+}\ensuremath{\rightarrow}{K}^{*+}{h}_{1}^{+}{h}_{2}^{\ensuremath{-}}$ (where ${h}_{1,2}=K$, $\ensuremath{\pi}$) decays are presented, using a data sample of $232\ifmmode\times\else\texttimes\fi{}{10}^{6}$ $\ensuremath{\Upsilon}(4S)\ensuremath{\rightarrow}B\overline{B}$ decays collected with the BABAR detector at the SLAC PEP-II asymmetric-energy $B$ factory. Using a maximum likelihood fit, the following branching fraction results were obtained: $\mathcal{B}({B}^{+}\ensuremath{\rightarrow}{K}^{*+}{K}^{+}{K}^{\ensuremath{-}})=(36.2\ifmmode\pm\else\textpm\fi{}3.3\ifmmode\pm\else\textpm\fi{}3.6)\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}6}$ and $\mathcal{B}({B}^{+}\ensuremath{\rightarrow}{K}^{*+}{\ensuremath{\pi}}^{+}{\ensuremath{\pi}}^{\ensuremath{-}})=(75.3\ifmmode\pm\else\textpm\fi{}6.0\ifmmode\pm\else\textpm\fi{}8.1)\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}6}$. Upper limits were set for $\mathcal{B}({B}^{+}\ensuremath{\rightarrow}{K}^{*+}{\ensuremath{\pi}}^{+}{K}^{\ensuremath{-}})&lt;11.8\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}6}$ and $\mathcal{B}({B}^{+}\ensuremath{\rightarrow}{K}^{*+}{K}^{+}{\ensuremath{\pi}}^{\ensuremath{-}})&lt;6.1\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}6}$ at 90% confidence level. The charge asymmetries for the decays ${B}^{+}\ensuremath{\rightarrow}{K}^{*+}{K}^{+}{K}^{\ensuremath{-}}$ and ${B}^{+}\ensuremath{\rightarrow}{K}^{*+}{\ensuremath{\pi}}^{+}{\ensuremath{\pi}}^{\ensuremath{-}}$ were measured to be ${\mathcal{A}}_{{K}^{*}KK}=0.11\ifmmode\pm\else\textpm\fi{}0.08\ifmmode\pm\else\textpm\fi{}0.03$ and ${\mathcal{A}}_{{K}^{*}\ensuremath{\pi}\ensuremath{\pi}}=0.07\ifmmode\pm\else\textpm\fi{}0.07\ifmmode\pm\else\textpm\fi{}0.04$, respectively. The first error quoted on branching fraction and asymmetry measurements is statistical and the second systematic.
Robust flexible LCDs with paintable technology (2004)

Abstract— In this article, second‐generation liquid‐crystal displays (LCDs) made by Paintable LCD technology is presented. With this technology, LCDs are manufactured by a sequence of simple coating and UV curing processes. Since the process can be carried out on plastic substrates and the stack of optical layers is only tens of micrometers thick, the resulting LCDs are ultra‐thin and flexible.
Application of the Lewis Acid-Lewis Base Bifunctional Asymmetric Catalysts to Pharmaceutical Syntheses: Stereoselective Chiral Building Block Syntheses of Human Immunodeficiency Virus (HIV) Protease Inhibitor and .BETA.3-Adenergic Receptor Agonist (2003)

Chiral building block syntheses of promising drugs were achieved using two types of catalytic stereoselective cyanosilylations of aldehydes promoted by Lewis acid-Lewis base bifunctional catalysts 1 and 2 as the key steps (diastereoselective cyanosilylation of amino aldehyde and enantioselective cyanosilylation). In the first part of this article, syntheses of chiral building blocks (6) of Atazanavir (3: human immunodeficiency virus (HIV) protease inhibitor) using the bifunctional catalyst 2 are discussed. The reaction of Boc-protected phenylalaninal 21 in the presence of 1 mol% catalyst 2 selectively afforded the anti isomer 22 as the major product (diastereomeric ratio=97 : 3), which was successively converted to the corresponding epoxide 6 in six steps. In the second part, we describe a chiral building block synthesis of beta(3)-adrenergic receptor agonists. The enantioselective cyanosilylation of 3-chlorobenzaldehyde (38) with 9 mol% catalyst 1 gave the chiral cyanohydrin 39, which was converted to beta-hydroxyethylamine 40 by reduction. Moreover, the chiral ligand of catalyst 1 could be recovered without column chromatography and reused without decreasing its activity.
Development of Novel Submicron Textured Polyether(Urethane Urea) for Decreasing Platelet Adhesion (2005)

Ventricular assist devices have proven to be a useful clinical option for providing circulatory support as a bridge to transplantation and a mode of destination therapy. Thromboembolism is prevented by designing devices that use blood interfaces that either encourage biological material deposition and strong adhesion, or discourage deposition via surface chemistry, surface finish, and fluid flow fields. Minimum continuous or periodic wall shear forces and maximum time at reduced shear are important, and sometimes difficult-to-satisfy, design constraints. We present an approach to reducing platelet adhesion via surface topography, reducing surface area for platelet-material interaction. Large areas of polyether(urethane urea) were textured with two different sizes of ordered pillar arrays via two-stage replication molding without affecting surface chemistry. Pillars had subplatelet dimensions designed to reduce the surface area a platelet may contact. Platelet adhesion was assessed in a physiologically relevant shear stress range from 0-10 dyn/cm2 using a rotating disk and compared to smooth control. Adhesion was highest from 0-5 dyn/cm2. Surface texturing reduced platelet adhesion without increasing platelet activation in bulk suspension. This study demonstrates that material surface texture is an additional variable that may be used to reduce platelet adhesion under low shear stresses potentially reducing thromboembolism.
Speckle Reduction of Reconstructions of Digital Holograms Using Gamma-Correction and Filtering (2017)

Speckle noise is inevitable in the process of acquiring of digital holograms. In this paper, a new approach is proposed to suppress the speckle noise in the digital hologram. The method is composed of two steps: 1) to enhance the noisy digital holograms by Gamma correction, and 2) to process the reconstructed images by filtering. It is demonstrated that the presented method can effectively reduce speckle noise in the digital hologram.
Rewards system developments: pay for performance in knowledge-intensive industries in China (2010)

Reward systems, and the role of 'performance' within them, are often a source of contention. However, post-2008 global 'credit crunch' and the perceived role of pay in that, systems have come under even more scrutiny. Yet, pay programmes are not determined simply by forces in the external environment. Instead, managers play a significant role in their adoption, modification and termination. Nevertheless, there is little literature on the contributions of line managers in pay for performance practices in the Chinese context. This paper explores line managers' perception of pay for performance and the key supports and barriers to their involvement in pay design and implementation. A multi-case study approach was conducted in China's non-public sector knowledge-intensive firms. The findings show that project intensification could be an important factor that impacts on line managers' understanding and responsibility in rewards systems and pay for performance.
New antiepileptic drugs (1989)

In contrast with the situation only a decade ago, a profusion of new potential AEDs has been introduced for world-wide clinical testing. Which, if any, of these compounds will be added to the physician's armamentarium against epileptic seizures is unknown, but the continuing flow of testable compounds augurs well for the future.
Noninvasive Fluorescence Detection of Hepatic and Renal Function (1998)

A noninvasive in vivo fluorescence detection scheme was employed to continuously monitor exogenous dye clearance from the vasculature. Differentiation between normal and impaired physiological function in a rat model was demonstrated for both liver and kidney. A fiber optic transmitted light from source to ear; a second fiber optic positioned near the ear transmitted the fluorescent light to a detector system. Two model dye systems were employed in this initial study. Indocyanine green, known to be exclusively cleared from the blood stream by the liver, was excited in vivo with laser light at 780 nm. The fluorescence signal was detected at 830 nm. A characteristic clearance curve of normal hepatic function was obtained. After a partial hepatectomy of the liver, the clearance curve was extended in time, as would be expected from reduced hepatic function. In addition, fluorescein labeled poly-D-lysine, a small polymer predominantly cleared from the blood stream by the kidney, was excited in vivo with laser light at 488 nm. The fluorescence signal was detected at 518 nm. A characteristic clearance curve of normal renal function was obtained. After a bilateral ligation of the kidneys, the clearance curve remained elevated and constant, indicating little if any clearance. Thus, the feasibility of a new noninvasive method for physiological function assessment was established. © 1998 Society of Photo-Optical Instrumentation Engineers.
The Disco App - A Mobile Social Tool for Sharing Automatically Collected Bluetooth Presence Data Between Friends (2009)

What can a smart phone do for you when you cannot or do not want to call?This master thesis describes an experiment in thought and technology.Through concept development and prototyping processes, the social factors of a location are subject for communication.A prototype demonstrates an untraditional way of using the smart phone as a social tool.Presence data -information about who is in the near presence -is tracked to share the social context of a user's location.This social location is dynamically changing, why it is particularly desirable when making phone calls to mobile users.The project results are the software prototype, and conclusions from briefing participants of a field test.The prototype, called The Disco App, models data of who you are hanging out with, and shares it with your friends.Test participants find the data a natural key to their friends' activities.
Synthesis and Characterization of a Triphenylphosphonium-conjugated Peroxidase Mimetic (2005)

Mitochondrial production of peroxides is a critical event in both pathology and redox signaling. Consequently their selective degradation within mitochondria is of considerable interest. Here we have explored the interaction of the peroxidase mimetic ebselen with mitochondria. We were particularly interested in whether ebselen was activated by mitochondrial glutathione (GSH) and thioredoxin, in determining whether an ebselen moiety could be targeted to mitochondria by conjugating it to a lipophilic cation, and in exploring the nature of ebselen binding to mitochondrial proteins. To achieve these goals we synthesized 2-[4-(4-triphenylphosphoniobutoxy) phenyl]-1,2-benzisoselenazol)-3(2H)-one iodide (MitoPeroxidase), which contains an ebselen moiety covalently linked to a triphenylphosphonium (TPP) cation. The fixed positive charge of TPP facilitated mass spectrometric analysis, which showed that the ebselen moiety was reduced by GSH to the selenol form and that subsequent reaction with a peroxide reformed the ebselen moiety. MitoPeroxidase and ebselen were effective antioxidants that degraded phospholipid hydroperoxides, prevented lipid peroxidation, and protected mitochondria from oxidative damage. Both peroxidase mimetics required activation by mitochondrial GSH or thioredoxin to be effective antioxidants. Surprisingly, conjugation to the TPP cation led to only a slight increase in the uptake of ebselen by mitochondria due to covalent binding of the ebselen moiety to proteins. Using antiserum against the TPP moiety we visualized those proteins covalently attached to the ebselen moiety. This analysis indicated that much of the ebselen present within mitochondria is bound to protein thiols through reversible selenenylsulfide bonds. Both MitoPeroxidase and ebselen decreased apoptosis induced by oxidative stress, suggesting that they can decrease mitochondrial oxidative stress. This exploration has led to new insights into the behavior of peroxidase mimetics within mitochondria and to their use in investigating mitochondrial oxidative damage.
ChemInform Abstract: Sterically Hindered Metal Alkenyls. Part 1. Synthesis, Reactions, and Crystal and Molecular Structures of Some Palladium and Platinum σ‐Alkenyls. (1987)

Abstract The σ‐alkenyl‐Pt and Pd complexes (II) are prepared from cis‐dichloro‐Pt or trans‐dichloro‐Pd complexes (I) and appropriate Li or Grignard reagents and incipient LiBr or MgBr 2 as shown.
Shedding light on flower development (2011)

Accurate development of the gynoecium, the female reproductive organ, is necessary to achieve efficient fertilization. In Arabidopsis, the correct patterning of the apical-basal axis of the gynoecium requires the establishment of a morphogenic gradient of auxin. This allows the production of specialized tissues, whose roles consist of attracting pollen, allowing pollen tube growth and protecting the ovules within the ovaries. Mutations in the bHLH transcription factor SPATULA (SPT) are known to impair the development of the apical tissues of the gynoecium. Here, we show that the spt phenotype is rescued by the removal of phytochrome B, and discuss how light signaling may control flower development.
ChemInform Abstract: (2 + 2)‐CYCLOADDITION OF A VINYL CATION (1979)

Abstract Umsetzung des Propens (Ia) in Cyclohexen mit Silbertrifluoracetat und Pyridin als Puffer führt über das Vinylkation (II) quantitativ zum Vinylester (Ib), während mit Silbertetrafluoroborat ein Gemisch aus den Propenen (Ic) und (Id) und dem Bicyclus (III) erhalten wird.
Banding artifact reduction for cardiac CT (2008)

One of problems with the current cardiac CT imaging is the banding artifacts, i.e., horizontal shifts in multiplanar reformatted (MPR) or three-dimensional (3-D) images. In this work, we propose a novel gating method that does not rely on electro-cardiogram but uses the similarity of image pixel values of heart images. Moreover, the proposed method optimizes the cardiac phase on a local basis. Evaluations with 10 patient data sets showed the substantial reduction of banding artifacts as well as the improved consistency in anatomical structures.
Synthesis of 2-thio-D-ribose and 2'-thioadenosine derivatives (1971)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of 2-thio-D-ribose and 2'-thioadenosine derivativesEdward M. Acton, Kenneth J. Ryan, and Leon GoodmanCite this: J. Org. Chem. 1971, 36, 18, 2646–2657Publication Date (Print):September 1, 1971Publication History Published online1 May 2002Published inissue 1 September 1971https://pubs.acs.org/doi/10.1021/jo00817a018https://doi.org/10.1021/jo00817a018research-articleACS PublicationsRequest reuse permissionsArticle Views326Altmetric-Citations41LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ChemInform Abstract: Bis(sulfonyl) Ketones: A New Oxyallyl Cation Source. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
60 nm gate length dual-Vt CMOS for high performance applications (2003)

In this work, we present a 60 nm gate length CMOS for high performance applications at the 0.13 /spl mu/m CMOS node. The technology utilizes 193 nm gate lithography, dual spacers with thin spacer before drain extension implant and L-shaped nitride spacer after drain extensions, and remote-plasma nitrided dielectric with 1.75 nm EOT. 10-15% improvement in drive current is achieved with lower series resistance by reduction of dopant loss and higher dopant activation, resulting in n- and pMOS I/sub drive/ of 1160 /spl mu/A//spl mu/m and 550 /spl mu/A//spl mu/m at 1.3 V at I/sub off/=100 nA//spl mu/m.
Development of a simple, low-cost, field-kit method to determine inorganic arsenic species in rice (2020)

Macromolecular Chemistry: The Second Century [Author Benefits](https://scimeetings.acs.org/?utm_source=pubs_content_marketing&utm_medium=website&utm_campaign=0320_MCF_NPI_Launch_Spring_Homepage&ref=pubs_content_marketing) [How to use SciMeetings](https://storage.googleapis.com/dl.morressier.com/acs/SciMeetings-ACSSpring2020-HowToGuide_M3020-Final.pdf) [Frequently Asked Questions](https://storage.googleapis.com/dl.morressier.com/acs/SciMtng_ACSNMSp2020_FAQ_M3120_Final.pdf)
The Empirical Foundations of the Arbitrage Pricing Theory II: The Optimal Construction of Basis Portfolios (1985)

The Arbitrage Pricing Theory (APT) of In this paper, we provide a comprehensive examination of the merits of various strategies for constructing basis portfolios that are, in principle, highly correlated with the common factors affecting security returns. Three main conclusions emerge from our study. First, increasing the number of securities included in the analysis dramatically improves basis portfolio performance. Our results indicate that factor models involving 750 securities provide markedly superior performance to those involving 30 or 250 securities. Second, comparatively efficient estimation procedures such as maximum likelihood and restricted maximum likelihood factor analysis (which imposes the APT mean restriction) significantly outperform the less efficient instrumental variables and principal components procedures that have been proposed in the literature. Third, a variant of the usual Fame-MacBeth portf oho formation procedure, which we call the minimum idiosyncratic risk portfolio formation procedure, outperformed the Fama-Macbeth procedure and proved equal to or better than more expensive quadratic programming procedures.
A three year time-series of volatile organic iodocarbons in Bedford Basin, Nova Scotia: a Northwestern Atlantic fjord (2018)

Abstract. We report weekly observations of volatile organic iodocarbons (CH3I, CH2ClI and CH2I2) over the time-period May 2015 to December 2017 from 4 depths in Bedford Basin, a coastal fjord (70 m deep) on the Atlantic coast of Canada. The fjord is subject to winter-time mixing, seasonal stratification and bloom dynamics, subsurface oxygen depletion, local input of freshwater and occasional intrusions of higher density water from the adjacent continental shelf. Near-surface concentrations showed strong seasonal and sub-seasonal variability which is compared with other coastal time-series. Relationships with other properties lead to the hypothesis that near-surface iodocarbon production is linked to reduction of iodate to iodide under conditions of post-bloom phytoplankton senescence, nutrient stress or viral lysis following seasonal disappearance of nutrients. The vertical variation of CH2I2 and CH2ClI within the upper 10m is consistent with rapid photolysis of CH2I2. Average annual sea-to-air fluxes (62 nmol m−2 day−1) of total volatile organic iodine were slightly higher than observed in other coastal and shelf time-series and polyiodinated compounds contributed 85 % of the total flux. Fluxes were subject to strong interannual variability (2–3X) as a result, mainly, of wind-speed variability. Near-surface net production of CH3I averaged 1.0 pmol L−1 day−1 and was similar to rates in the English Channel but an order of magnitude higher than in shallow waters of the Kiel Fjord, Germany, possibly due to higher microbial degradation in the latter. The near-bottom (60 m) time-series showed evidence for CH3I production associated with organic matter degradation, and a possible switch from production of CH3I via an alkylation pathway to production of CH2I2 by a haloform-type reaction. Near-bottom CH3I production varied strongly between years but was generally ca. 20 times lower than near-surface production. Post-intrusion decreases of iodocarbons at 60 m suggested removal timescales of 14, 65 and 70 days for CH3I, CH2I2 and CH2ClI respectively.
Could lysine supplementation prevent Alzheimer&rsquo;s dementia? A novel hypothesis (2010)

There is a growing body of evidence that implicates the herpes simplex type 1 virus (HSV-1) in the development of Alzheimer's dementia (AD). HSV-1 has been found to be present in the cerebrum of the great majority of older adults, and in many of the same areas of the brain that are affected by AD. When active, the virus may contribute to the formation of the neuro-fibrillary tangles and amyloid plaques characteristic of AD. Like AD, HSV-1 encephalitis may cause long term memory loss. HSV-1 replication is suppressed in lysine-rich/arginine - poor environments, and population studies suggest that diets high in lysine and low in arginine may be associated with lower rates of AD. There are no prospective studies of the efficacy of lysine supplementation to prevent or reduce the incidence of AD. Supplementation with adequate doses of lysine could prevent the development of AD.
CuO NPs-induced damage to testes and deregulation of the antioxidant system in wild terrestrial organism Blaps sulcata (Coleoptera: Tenebrionidae) (2022)

Considering the constantly growing areas of CuO NPs applications, including agriculture, horticulture, and forestry, one can suspect that the balance in soil ecosystems can be seriously disturbed. Such a scenario causes serious concern about the fate of wild animals inhabiting these ecosystems. The study aimed to estimate the effects of a single exposure of Blaps sulcata, a valuable indicator of terrestrial environments pollution, on copper oxide nanoparticles (CuO NPs), emphasizing changes in the gonads. Survival curves were estimated, and LD50 was calculated as 0.0352 mg ∙ g-1b.w. Moreover, 30 days after the CuO NPs injection, an increased accumulation of Cu in the testes and numerous degenerative changes in this organ was found. These changes were accompanied by an intensification of apoptosis, DNA damage, and dysregulation of the antioxidant system, which was manifested by an increase in the activity of superoxide dismutase (SOD) with a simultaneous decrease in the activity of catalase (CAT). Reduced acetylcholinesterase (AChE) activity was also observed, suggesting that the exposed insects may have problems with neurotransmission and bear negative behavioral consequences - from obtaining food and avoiding predators to mating and reproductive behavior. The far-reaching effects of exposure of wild animals, including terrestrial insects, to CuO NPs, may be reproductive abnormalities and disturbances in populations and ecosystems. Thus, using CuO NPs, including fertilizers, growth stimulators, and pesticides, must be carefully considered in the future.