gebhart/patrepeval huggingface dataset:
Visualising the digital twin using web services and augmented reality (2016)

As the number of network connected devices in an industrial system increases, the management and handling of all the information generated become a challenge. In this work we explore concepts of Cyber-Physical System model the virtual part of industrial devices (sensor, machines, CLPs) using the Digital Twin concept and propose an architecture based on web services for accessing their data. We present a case study where an Augmented Reality system access the Twin Model data via web services and display real-time information to the user. Moreover, we present a review of how the involved concepts, which have a strong computational background, relate to industrial applications and how they can expand the possibility of services and business models.
Total Antioxidant Levels are Low During Active TB and Rise with Anti‐tuberculosis Therapy (2004)

In tuberculosis, oxidative stress is a result of tissue inflammation, poor dietary intake of micronutrients due to illness, free radical burst from activated macrophages, and anti-tuberculosis drugs. These free radicals may in turn contribute towards pulmonary inflammation if not neutralized by antioxidants. The total antioxidant status (TAS) of individuals is a function of dietary, enzymatic, and other systemic antioxidants and is therefore an indicator of the free radical load. Our aim was to evaluate the TAS of healthy and M. tuberculosis-infected persons from a high TB incidence community, as well as tuberculosis patients at various stages of antituberculosis drug treatment and to correlate results with plasma micronutrient levels. Blood plasma samples from TB infected patients and following antituberculosis drug treatment were assayed for TAS, vitamins A, E and Zinc. Statistical analysis of results was by one-way ANOVA and the Tukey multiple comparison post test. Active TB patients showed a significantly lower TAS (P < 0.001) compared to the community controls. We also show that TAS values increase during therapy. Results correlated with micronutrients vitamin A and zinc but vitamin E remained unaffected. We suggest that total antioxidant status of TB patients should be considered for more effective disease control and that diets low in antioxidants may render individuals susceptible to tuberculosis.
Boundary-induced reentry in homogeneous excitable tissue (2008)

Heterogeneity of cardiac electrical properties can lead to heart rhythm disorders. Numerical studies have shown that stimuli chosen to maximize dynamic heterogeneity terminate wave propagation. However, experimental investigations suggest that similar sequences induce fragmentation of the wave fronts, rather than complete wave block. In this paper we show that an insulating boundary in an otherwise homogeneous medium can disrupt dynamically induced wave block by breaking a symmetry in the spatial pattern of action potential duration, leading to unidirectional block and reentrant activation.
Impact of Infectious Burden on Progression of Carotid Atherosclerosis (2002)

Our results support the hypothesis that the number of infectious pathogens to which an individual has been exposed independently contributes to the progression of carotid atherosclerosis.
A vision for climate services in NOAA (2009)

Climate change is widely regarded as among the most challenging environmental issues ever faced by humanity. The National Oceanic and Atmospheric Administration (NOAA) is working to enhance its climate services by creating a comprehensive and coordinated approach to providing information to support adaptation and mitigation of climate change and its impacts, including those important for human life and coastal/marine ecosystems. NOAA has recently published a report entitled, A Vision for Climate Services in NOAA, (available at www.climate.noaa.gov/pdf/ GandPdocumentOct21.pdf) that provides a set of goals and principles for these services from the view of a group of NOAA scientists and related experts. Below is an abridged version of this document, with particular emphasis on ecosystem and fisheries considerations.
System overview and special features of FATE: fuzzy logic automatic transmission expert system (2002)

Although the engineering of automatic transmission is by now a mature field, gears do not always shift properly under certain driving conditions. As a basis for a more human-friendly controller, we propose FATE, a fuzzy logic gear shift selection expert system.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Molecular Structures of Magnesium Dichloride Sheets and Nanoballs (2004)

The structures and relative stabilities of (MgCl(2))(n)() sheetlike clusters and nanoballs were studied by quantum chemical methods. The sheets as discrete molecules were studied up to Mg(100)Cl(200). Their stabilities increase systematically as a function of the size of the sheet. Periodic ab initio calculations were performed for (001) monolayer sheets of alpha- and beta-MgCl(2), beta-sheet being slightly favored. Nanoballs were constructed from Archimedean polyhedra, producing tetrahedral, octahedral, and icosahedral symmetries, and were studied up to Mg(60)Cl(120). Nanoballs prefer to take the shape of truncated cuboctahedron (Mg(48)Cl(96)). Comparisons to sheetlike clusters and periodic calculations suggest that magnesium dichloride nanoballs are stable.
Are Rule-based Syllabification Methods Adequate for Languages with Low Syllabic Complexity? The Case of Italian (2007)

Syllabification information is a valuable component in speech synthesis systems. Linguistic rule-based methods have been assumed to be the best technique for determining the syllabification of unknown words. This has recently been shown to be incorrect for the English language where data-driven algorithms have been shown to outperform rule-based methods. It may be possible, however, that data-driven methods are only better for languages with complex syllable structures. In this paper, three rule-based automatic syllabification systems are compared and two data-driven (Syllabification by Analogy and the Look-Up Procedure) on a language with lower syllabic complexity- Italian. Using a leave-one-out procedure on 44,720 words, the best data-driven algorithm (Syllabification by Analogy) achieved 97.70 % word accuracy while the best rule-based method correctly syllabified 89.77 % words. These results show that data-driven methods can also outperform rule-based methods on Italian syllabification, indicating that these may be the best approaches to the syllabification component of speech synthesis systems.
Effects of manganese and zirconium on microstructures and mechanical properties of 6061 alminum alloys. (1998)

The addition of manganese and zirconium is effective to remove iron from the melt of the recycled aluminum. In such a case, manganese and zirconium possibly remain in the melt. The influence of the remaining elements on various properties of aluminum alloys has not been clarified. In this study, effects of the remaining manganese and zirconium on the microstructures and mechanical properties of the 6061 aluminum alloy were investigated. The compound of Al8(Cr, Mn, Fe)2Si crystallizes if manganese is added to the 6061 aluminum alloy, resulting in the reduced solid solubility of silicon in the matrix. Since silicon contributes to age hardening of the 6061 aluminum alloy by forming metastable phases with magnesium the addition of manganese thus causes the decreases in the 0.2% proof stress and tensile strength of the 6061 alloy. Zirconium added to the 6061 aluminum alloy is partly retained as a solid solution in the matrix and the remainder forms Al–Zr or Al–Zr–Si compounds. The amounts of these compounds, however, are very small, and their effects on the tensile properties are negligible. The manganese content in the 6061 aluminum alloy with 0.3%Zr should be less than 0.4mass% to guarantee the tensile properties specified in JIS.
Relatório anual da Escola Superior de Agricultura «Luiz de Queiroz», relativo ao exercício de 1944 (1945)

27Em 1944, o ano letivo teve seu início a 13 de março, para cuja data fora convocada a assembléia de abertura dos cursos.Nessa solenidade, o prof.João Bierrenbach de Lima pronunciou a aula inaugural sobre "Cooperativismo"na presença de grande número de professores, alunos e funcionários.Em conseqüência da Lei Orgânica do Ensino Secundário (Decreto-lei n. 4.244, de 9 de Abril de 1942) ficou extinto o Colé-
Synthesis of 5, 6-Dichloro-Benzimidazole-(2′, 5′)-Nucleotide Trimer (1985)

Abstract The chemical synthesis of the trimeric 5, 6-dichloro-1-β-D-ribofuranosylbenzimidazole-(2′, 5′)-diphosphate using the phosphotriester approach is described.
Development of a prostate cDNA microarray and statistical gene expression analysis package (2000)

A cDNA microarray comprising 5184 different cDNAs spotted onto nylon membrane filters was developed for prostate gene expression studies. The clones used for arraying were identified by cluster analysis of > 35 000 prostate cDNA library-derived expressed sequence tags (ESTs) present in the dbEST database maintained by the National Center for Biotechnology Information. Total RNA from two cell lines, prostate line 8.4 and melanoma line UACC903, was used to make radiolabeled probe for filter hybridizations. The absolute intensity of each individual cDNA spot was determined by phosphorimager scanning and evaluated by a bioinformatics package developed specifically for analysis of cDNA microarray experimentation. Results indicated 89% of the genes showed intensity levels above background in prostate cells compared with only 28% in melanoma cells. Replicate probe preparations yielded results with correlation values ranging from r = 0.90 to 0.93 and coefficient of variation ranging from 16 to 28%. Findings indicate that among others, the keratin 5 and vimentin genes were differentially expressed between these two divergent cell lines. Follow-up northern blot analysis verified these two expression changes, thereby demonstrating the reliability of this system. We report the development of a cDNA microarray system that is sensitive and reliable, demonstrates a low degree of variability, and is capable of determining verifiable gene expression differences between two distinct human cell lines. This system will prove useful for differential gene expression analysis in prostate-derived cells and tissue.
Maternal nicotine dependence is associated with longitudinal increases in child obesogenic eating behaviors (2019)

Maternal nicotine dependence may be a transdiagnostic risk factor that identifies children at risk for reward-driven, obesogenic eating behavior.
Inflammasome activation during spontaneous preterm labor with intra‐amniotic infection or sterile intra‐amniotic inflammation (2018)

Inflammasome activation occurs in the settings of intra-amniotic infection and sterile intra-amniotic inflammation during spontaneous preterm labor.
Supervised Compression Of Multivariate Time Series Data (2006)

Publication in the conference proceedings of EUSIPCO, Florence, Italy, 2006
TEMPO as a Hydrogen Atom Transfer Catalyst for Aerobic Dehydrogenation of Activated Alkanes to Alkenes (2022)

2,2,6,6-Tetramethylpiperidine-<i>N</i>-oxyl (TEMPO) has been extensively utilized as a radical scavenger or an oxidation catalyst. In contrast, TEMPO as a hydrogen atom transfer (HAT) catalyst has rarely been studied. Here, we report that TEMPO, as the HAT catalyst, homolytically cleaves benzylic or allylic C-H bonds to give the corresponding alkyl radicals. Benefiting from the dual roles played by TEMPO as the HAT catalyst and the radical scavenger, the highly challenging aerobic dehydrogenation of activated alkanes to alkenes is successfully developed.
The Learning Priority (2013)

Texte issu de contributions à l'"International conference on adult learning" (ICAL) tenue à Paris du 27 au 29 mai 2012.
A cross-language study of vowel spaces and interference (1987)

This is a study of the spectral characteristics of the vowels of German and modern Greek in relation to those of American English. Two native speakers of German produced 18 words containing the short and long vowels of German, and two native speakers of Greek produced five words containing the five pure vowels of Greek. All speakers also produced nine English words containing the nine simple vowels of English. Vowel target zones for German, Greek, and foreign-accented English are established within the auditory perceptual theory [J. D. Miller, J. Acoust. Soc. Am. Suppl. 1 76, S79 (1984)] and compared to the target zones of native speakers of English. A metric of the distance between the foreign, foreign-accented English, and native English target zones will be developed. Perception experiments are planned to obtain both identification scores and paired-comparison ratings of foreign accentedness. The positions of vowels in both the native and acquired language will be correlated with these ratings to determine if an objective measure of foreign accent and phonetic interference can be derived.
Human serum biotinidase. cDNA cloning, sequence, and characterization. (1994)

Biotinidase (EC 3.5.1.12) catalyzes the hydrolysis of biocytin, the product of biotin-dependent carboxylase degradation, to biotin and lysine. Biotinidase deficiency is an inherited metabolic disorder of biotin recycling that is characterized by neurological and cutaneous abnormalities, and can be successfully treated with biotin supplementation. Sequences of tryptic peptides of the purified human serum enzyme were used to design oligonucleotide primers for polymerase chain reaction amplification from human hepatic total RNA to generate putative biotinidase cDNA fragments. Sequence analysis of a cDNA isolated from a human liver library by plaque hybridization with the largest cDNA probe revealed an open reading frame of 1629 bases encoding a protein of 543 amino acid residues, including 41 amino acids of a potential signal peptide. Comparison of the open reading frame with the known biotinidase tryptic peptides and recognition of the expressed protein encoded by this cDNA by monoclonal antibodies prepared against purified biotinidase demonstrated the identity of this cDNA. Southern analyses suggested that biotinidase is a single copy gene and revealed that human cDNA probes hybridized to genomic DNA from mammals, but not from chicken or yeast. Northern analysis indicated the presence of biotinidase mRNA in human heart, brain, placenta, liver, lung, skeletal muscle, kidney, and pancreas.
Synthesis and Antitumor Evaluation of Novel Derivatives of 6-Amino-2-phenylbenzothiazoles (2006)

Novel derivatives of 6-amino-2-phenylbenzothiazole bearing different substituents (amino, dimethylamino or fluoro) on the phenyl ring were prepared as the corresponding hydrochloride salts. 6-Nitro-2-(substituted-phenyl)benzothiazoles (1-6) were synthesized by condensation reactions of substituted benzaldehydes with 2-amino-5-nitrothiophenol. Nitro derivatives were reduced to the amino derivatives with SnCl(2)/HCl. Water soluble hydrochloride salts of 6-amino-2-(substituted-phenyl)benzothiazole (13-19)were prepared using concentrated or gaseous HCl. Compounds 13-19 were found to exert cytostatic activities against malignant human cell lines: cervical (HeLa), breast (MCF-7),colon (CaCo-2), laryngeal carcinoma (Hep-2), and normal human fibroblast cell lines (WI-38).
The Role of Drug–Polymer Hydrogen Bonding Interactions on the Molecular Mobility and Physical Stability of Nifedipine Solid Dispersions (2014)

We investigated the influence of drug-polymer hydrogen bonding interactions on molecular mobility and the physical stability in solid dispersions of nifedipine with each of the polymers polyvinylpyrrolidone (PVP), hydroxypropylmethyl cellulose (HPMCAS), and poly(acrylic acid) (PAA). The drug-polymer interactions were monitored by FT-IR spectroscopy, the molecular mobility was characterized using broadband dielectric spectroscopy, and the crystallization kinetics was evaluated by powder X-ray diffractometry. The strength of drug-polymer hydrogen bonding, the structural relaxation time, and the crystallization kinetics were rank ordered as PVP > HPMCAS > PAA. At a fixed polymer concentration, the fraction of the drug bonded to the polymer was the highest with PVP. Addition of 20% w/w polymer resulted in ∼65-fold increase in the relaxation time in the PVP dispersion and only ∼5-fold increase in HPMCAS dispersion. In the PAA dispersions, there was no evidence of drug-polymer interactions and the polymer addition did not influence the relaxation time. Thus, the strongest drug-polymer hydrogen bonding interactions in PVP solid dispersions translated to the longest structural relaxation times and the highest resistance to drug crystallization.
COLLAPSE, SYMMETRY BREAKING, AND HYSTERESIS IN SWIRLING FLOWS (1999)

▪ Abstract The paper reviews striking features of swirling flows—collapse, swirl generation, vortex breakdown, hysteresis, and axisymmetry breaking—and the mechanisms involved with the help of conical similarity solutions of the Navier-Stokes equations. The strong accumulation of axial and angular momenta, observed in tornadoes and flows over delta wings, corresponds to collapse, i.e. the singularity development in these solutions. Bifurcation of swirl explains the threshold character of swirl development in capillary and electrovortex flows. Analytical solutions for fold catastrophes and hysteresis reveal why there are so few stable states and why the jump transitions between the states occur—features typical of tornadoes, of flows over delta wings, and in vortex devices. Finally, the divergent instability explains such effects as the splitting of a tornado and the development of spiral branches in tree and near-wall swirling flows.
A Haystack Full of Needles: Scalable Detection of IoT Devices in the Wild (2020)

Consumer Internet of Things (IoT) devices are extremely popular, providing users with rich and diverse functionalities, from voice assistants to home appliances. These functionalities often come with significant privacy and security risks, with notable recent large scale coordinated global attacks disrupting large service providers. Thus, an important first step to address these risks is to know what IoT devices are where in a network. While some limited solutions exist, a key question is whether device discovery can be done by Internet service providers that only see sampled flow statistics. In particular, it is challenging for an ISP to efficiently and effectively track and trace activity from IoT devices deployed by its millions of subscribers --all with sampled network data. In this paper, we develop and evaluate a scalable methodology to accurately detect and monitor IoT devices at subscriber lines with limited, highly sampled data in-the-wild. Our findings indicate that millions of IoT devices are detectable and identifiable within hours, both at a major ISP as well as an IXP, using passive, sparsely sampled network flow headers. Our methodology is able to detect devices from more than 77% of the studied IoT manufacturers, including popular devices such as smart speakers. While our methodology is effective for providing network analytics, it also highlights significant privacy consequences.
[Cutaneous cancers after organ transplantation]. (2007)

Drug-induced immunosuppression is the necessary corollary of organ transplantation. This situation is responsible for an increased risk of both infection and neoplasia. Cutaneous carcinomas are the most frequent malignancies developing after organ transplantation. The usual squamous to basal cell carcinoma ratio is increased and reversed compared to the general population. Carcinomas primarily result from the combination of cumulative sun exposure, fair skin phototype and effects of immunosuppressive drugs. These treatments impair the systemic immunosurveillance and may exert a direct carcinogenic effect. The severity of these carcinomas is due to their multiplicity and to the occurrence of more aggressive lesions. Prevention relies on a strict adherence to sun protection after transplantation, and on refined immunosuppressive strategies. The treatment of the neoplastic lesions is based on their early and complete excision with histological control of the nature of the neoplasm, the safety surgical margins, and the determination of prognostic factors.
Alu elements shape the primate transcriptome by cis-regulation of RNA editing (2014)

We propose a model whereby primate-specific editing is induced by adjacent Alu elements that function as recruitment elements for the ADAR editing enzymes. The enrichment of site-selective editing with potentially functional consequences on the expression of transcription factors indicates that editing contributes more profoundly to the transcriptomic regulation and repertoire in primates than previously thought.
Depth dose measurements in water for 11C and 10C beams with therapy relevant energies (2022)

Owing to the favorable depth-dose distribution and the radiobiological properties of heavy ion radiation, ion beam therapy shows an improved success/toxicity ratio compared to conventional radiotherapy. The sharp dose gradients and very high doses in the Bragg peak region, which represent the larger physical advantage of ion beam therapy, make it also extremely sensitive to range uncertainties. The use of <i>β</i> <sup>+</sup>-radioactive ion beams would be ideal for simultaneous treatment and accurate online range monitoring through PET imaging. Since all the unfragmented primary ions are potentially contributing to the PET signal, these beams offer an improved image quality while preserving the physical and radiobiological advantages of the stable counterparts. The challenging production of radioactive ion beams and the difficulties in reaching high intensities, have discouraged their clinical application. In this context, the project Biomedical Applications of Radioactive ion Beams (BARB) started at GSI (Helmholtzzentrum für Schwerionenforschung GmbH) with the main goal to assess the technical feasibility and investigate possible advantages of radioactive ion beams on the pre-clinical level. During the first experimental campaign <sup>11</sup>C and <sup>10</sup>C beams were produced and isotopically separated with the FRagment Separator (FRS) at GSI. The <i>β</i> <sup>+</sup>-radioactive ion beams were produced with a beam purity of 99% for all the beam investigated (except one case where it was 94%) and intensities potentially sufficient to treat a small animal tumors within few minutes of irradiation time, ∼ 10<sup>6</sup> particle per spill for the <sup>10</sup>C and ∼ 10<sup>7</sup> particle per spill for the <sup>11</sup>C beam, respectively. The impact of different ion optical parameters on the depth dose distribution was studied with a precision water column system. In this work, the measured depth dose distributions are presented together with results from Monte Carlo simulations using the FLUKA software.
Compressed sensing based interior tomography (2009)

While conventional wisdom is that the interior problem does not have a unique solution, by analytic continuation we recently showed that the interior problem can be uniquely and stably solved if we have a known sub-region inside a region of interest (ROI). However, such a known sub-region is not always readily available, and it is even impossible to find in some cases. Based on compressed sensing theory, here we prove that if an object under reconstruction is essentially piecewise constant, a local ROI can be exactly and stably reconstructed via the total variation minimization. Because many objects in computed tomography (CT) applications can be approximately modeled as piecewise constant, our approach is practically useful and suggests a new research direction for interior tomography. To illustrate the merits of our finding, we develop an iterative interior reconstruction algorithm that minimizes the total variation of a reconstructed image and evaluate the performance in numerical simulation.