gebhart/patrepeval huggingface dataset:
Anticardiolipin antibodies block the inhibition by beta 2-glycoprotein I of the factor Xa generating activity of platelets. (1993)

Antiphospholipid antibodies, defined either by lupus anticoagulant (LA) activity or positive anticardiolipin immunoabsorbent assay (ACA) are associated with a predisposition to thromboses, recurrent fetal loss or thrombocytopenia. The mechanisms for these predispositions remain undefined. We have enriched immunoglobulin fractions from two patient plasmas to obtain antibodies with LA activity but no ACA, or conversely, with ACA positivity but no LA, in order to investigate in vitro characteristics which might explain a thrombotic propensity. beta 2-glycoprotein I (beta 2-GPI), the plasma cofactor required for ACA binding to negatively charged phospholipid, has previously been shown to inhibit prothrombinase generation in the presence of activated platelets (8). We now report that beta 2-GPI, at physiological concentrations, inhibits the generation of factor Xa in the presence of activated gel-filtered platelets. Further, ACA interferes with this inhibition, resulting in protracted, unopposed factor Xa generation. This interference with beta 2-GPI, a natural anticoagulant component of plasma, is potentially prothrombotic. LA immunoglobulins behave differently and inhibit factor Xa generation in a manner similar to beta 2-GPI. These findings provide the basis for a previously unsuspected mechanism for thrombosis in patients with aPL.
Bottlebrush-architectured poly(ethylene glycol) as an efficient vector for RNA interference in vivo (2019)

Nonhepatic delivery of small interfering RNAs (siRNAs) remains a challenge for development of RNA interference-based therapeutics. We report a noncationic vector wherein linear poly(ethylene glycol) (PEG), a polymer generally considered as inert and safe biologically but ineffective as a vector, is transformed into a bottlebrush architecture. This topology provides covalently embedded siRNA with augmented nuclease stability and cellular uptake. Consisting almost entirely of PEG and siRNA, the conjugates exhibit a ~25-fold increase in blood elimination half-life and a ~19-fold increase in the area under the curve compared with unmodified siRNA. The improved pharmacokinetics results in greater tumor uptake and diminished liver capture. Despite the structural simplicity these conjugates efficiently knock down target genes in vivo without apparent toxic and immunogenic reactions. Given the benign biological nature of PEG and its widespread precedence in biopharmaceuticals, we anticipate the brush polymer-based technology to have a significant impact on siRNA therapeutics.
Switched Ethernet Networking over LEO Satellite (2005)

Satellite onboard switching capabilities, and their possibility to enable "over-the-air" networks, is a strongly innovative achievement of modern satellite communication. The exploitation of satellite networking is especially relevant in the case of Low Earth Orbit satellites (LEO), where the reduced latency makes a LEO mesh network highly appealing and competitive with terrestrial solutions also in terms of performance. However, while the idea of a LEO mesh network is well understood, we are far from an ultimate answer on which is the best and more appropriate networking solution for moving LEO satellite network nodes. This paper promotes the adoption of existing layer-2 networking solutions over LEO networks. We believe that LEO networking may leverage from already existing and well understood layer-2 switching mechanisms, thus allowing, on one side, onboard deployment of switching fabrics and solutions already developed for terrestrial networks, and, on the other side, seamless interoperation with terrestrial networks. Specifically, as technical contribution of this paper, we show how 802.1Q switching solutions (i.e. Ethernet Virtual LAN switching) may be adapted, with limited modification effort, to operate in a LEO scenario. Moreover, we propose an innovative approach for frame routing over a mesh of multiple spanning trees (802.1s), especially devised to dramatically enhance the performance of legacy 802.1Q solutions in the presence of moving LEO nodes.
The Development of Functional Mesocrystals for Energy Harvesting, Storage, and Conversion (2017)

Higher-ordered semiconductors have attracted extensive research interest as an adopted engineering for active solar energy harvesting, storage, and conversion. It is well-known that the effective separation and anisotropic migration of photogenerated charges are the basic driven force required for superior efficiency. However, the morphology and stoichiometric variation of these semiconductors play essential roles in their physicochemical properties of bulk and surface, especially for efficient interparticle or interfacial charge transfer. To this point, the strategy of controlling the topotactic transformation toward superstructures with optimized functionality is preferable for a wide range of optoelectronic and catalytic engineering applications. In this Minireview, we provide an overview of the crystal orientation, synthetic engineering, functional applications, and spatial and temporal charge dynamics in TiO<sub>2</sub> mesocrystals and others. The viewpoint of in-depth understanding of the structure-related kinetics would offer an opportunity for design of versatile mesocrystal semiconductors sought-after for potential applications.
DNA fingerprinting in the Chinese with an oligonucleotide probe (GTG)5. (1992)

DNA fingerprinting is a very powerful tool that enables specific identification of individuals. In order to study fingerprinting patterns in the Chinese, the oligonucleotide probe designed by Epplen et al was used. Peripheral blood leukocyte DNA was digested with restriction enzyme Hinf I and probed by (GTG)5. Normal females and males were tested; all revealed very different DNA fingerprints. Most of the discernible bands in the gel were polymorphic; there was no specific association between any polymorphic band and the sex of the individual tested. In situ gel-hybridization was used with the oligonucleotide probe, and after electrophoresis, all procedures could be completed within one working day. Three patients who had received bone marrow transplants from their respective siblings had the same fingerprints as their donors. The inheritance of all bands from either the father or mother proved parents' authenticity. DNA fingerprinting with a oligonucleotide probe is obviously a useful technique. Clinical application may include engraftment monitoring, zygosity determination and paternity testing.
True incidence of vaginal vault prolapse. Thirteen years of experience. (1999)

Our data show that there is a low incidence of vaginal vault prolapse when hysterectomy is performed in the absence of defects in pelvic support. A comparison of our method and those described in the literature to determine the incidence of vaginal vault prolapse showed that this event is often underevaluated if long-term follow-up after hysterectomy is not carried out.
Electromagnetic field measurement method to generate radiation map (2012)

An electromagnetic field monitoring method is proposed and tested during measurement campaigns at urban zone of Bucaramanga city, Colombia. Communication tools are used integrated with a Geographic Information System, an online server and the access to data base by means of web services. A set of measuring equipment is connected to the communication system in order to manage a great amount of information and to analyze it, but specially to establish whether the international recommendations are being met or not. It is also possible to know which kind of factors are contributing to radiation level increasing by using NARDA field meters, Spectrum analyzers and other possible equipment, all of them controlled remotely through fixed or mobile terminals. Based on measured points, a continuous surface of radiation levels is plotted on a geographic map by using an interpolation algorithm.
Dietary Glucose Consumption Promotes RALDH Activity in Small Intestinal CD103+CD11b+ Dendritic Cells (2020)

Retinal dehydrogenase (RALDH) enzymatic activities catalyze the conversion of vitamin A to its metabolite Retinoic acid (RA) in intestinal dendritic cells (DCs) and promote immunological tolerance. However, precise understanding of the exogenous factors that act as initial trigger of RALDH activity in these cells is still evolving. By using germ-free (GF) mice raised on an antigen free (AF) elemental diet, we find that certain components in diet are critically required to establish optimal RALDH expression and activity, most prominently in small intestinal CD103<sup>+</sup>CD11b<sup>+</sup> DCs (siLP-DCs) right from the beginning of their lives. Surprisingly, systematic screens using modified diets devoid of individual dietary components indicate that proteins, starch and minerals are dispensable for this activity. On the other hand, in depth comparison between subtle differences in dietary composition among different dietary regimes reveal that adequate glucose concentration in diet is a critical determinant for establishing RALDH activity specifically in siLP-DCs. Consequently, pre-treatment of siLP-DCs, and not mesenteric lymph node derived MLNDCs with glucose, results in significant enhancement in the <i>in vitro</i> generation of induced Regulatory T (iTreg) cells. Our findings reveal previously underappreciated role of dietary glucose concentration in establishing regulatory properties in intestinal DCs, thereby extending a potential therapeutic module against intestinal inflammation.
Corrigendum to “Rondeau E, Scully M, Ariceta G, Barbour T, Cataland S, Heyne N, Miyakawa Y, Ortiz S, Swenson E, Vallee M, Yoon S-S, Kavanagh D and Haller H; on behalf of the 311 Study Group. The long-acting C5 inhibitor, Ravulizumab, is effective and safe in adult patients with atypical hemolytic uremic syndrome naïve to complement inhibitor treatment.” Kidney Int. 2020;97:1287–1296 (2021)

The authors regret that 2 investigators were not included in the 311 Study Group. Members of the 311 Study Group are listed in the Appendix. The authors would like to apologize for any inconvenience caused.
Fusion Research and Plasma Physics: A Story of Paradigms (1987)

Marshall Rosenbluth's contributions to the magnetic mirror research program are briefly reviewed. (MOW)
Application of an optical torque sensor to a vehicle power steering system (1992)

The author describes the application of an optical torque sensor in a concept electric power assisted steering (EPAS) system for small cars which has been developed at Lucas Advanced Engineering Centre. A novel design of sensor enables the required performance to be obtained while still having the potential of low-cost manufacture compatible with the automotive market. An EPAS system uses an electric motor to provide the steering assistance, with control from an electronic torque sensor. Power is only consumed when assistance is actually required, thus improving fuel consumption, and the installation complexity and size are reduced. It is also possible to provide additional functions such as road-speed dependence and to interface with other vehicle systems such as active suspension at little extra cost. The system comprises a motor and epicyclic gearbox assembly mounted concentrically on the steering column. The torque sensor is incorporated within this assembly. An electronic control unit (ECU) processes the signals from the torque sensor and drives the motor.<
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Servicescapes: The Impact of Physical Surroundings on Customers and Employees (1992)

A typology of service organizations is presented and a conceptual framework is advanced for exploring the impact of physical surroundings on the behaviors of both customers and employees. The ability of the physical surroundings to facilitate achievement of organizational as well as marketing goals is explored. Literature from diverse disciplines provides theoretical grounding for the framework, which serves as a base for focused propositions. By examining the multiple strategic roles that physical surroundings can exert in service organizations, the author highlights key managerial and research implications.
Band structure and density of states of. beta. -silicon nitride (1980)

The electronic energy band structure of ..beta..-Si/sub 3/N/sub 4/ has been calculated using the first principles LCAO method. The bottom of the Conduction Band (CB) is at GAMMA and the top of the valence band (VB) is located along GAMMAA line. The very flat top VB along GAMMAA accounts for a large hole effective mass. The indirect band gap obtained is very close to the experimental value of 5.2 eV. The density of states (DOS) and partial DOS are also obtained and are in good agreement with photoemission data. In the VB region from -20. to -14. eV the states are entirely composed of N 2s states while in the range from -10.5 eV up, the states are predominately N 2p in character. In the CB region, the DOS is dominated by Si 3s and 3p orbital components. These results are consistent with charge analysis which indicates that on average, 0.56 electron is transferred from Si to N per Si-N bond.
Leak current estimated from the shot noise in magnetic tunneling junctions (2014)

We performed the shot noise measurement in epitaxial Fe/MgO/Fe-based magnetic tunneling junctions (MTJs) with various MgO thicknesses between 1.1 nm and 1.625 nm. While the Fano factor to characterize the shot noise is very close to 1 in MTJs with MgO barrier thicker than 1.2 nm, the magnetic configuration-dependent reduction of the Fano factor for MTJs with thin MgO barrier was observed, which is mainly due to the existence of leakage current. By using a simple parallel circuit model, we demonstrated that the contribution of the leak current can be sensitively derived from the shot noise.
The effectiveness of 10 years of interventions to control postoperative bleeding in adult cardiac surgery (2016)

Despite a continuous increase in the bleeding risk profile, the application of a bundle of interventions is effective in controlling postoperative bleeding and related complications. Platelet transfusions remain unreplaceable in the present scenario.
The LysR‐type regulator SftR is involved in soil survival and sulphate ester metabolism in Pseudomonas putida (2002)

Sulphate esters make up a large proportion of the available sulphur in agricultural soils, and many pseudomonads can desulphurize a range of aryl- and alkylsulphate esters to provide sulphur for growth. After miniTn5 transposon mutagenesis of Pseudomonas putida S-313, we isolated 19 mutants that were defective in cleavage of the chromogenic sulphate ester 5-bromo-4-chloro-3-indoxylsulphate (X-sulphate). Analysis of these strains revealed that they carried independent insertions in a gene cluster that comprised genes for a sulphate ester/sulphonate transporter (atsRBC) a LysR-type regulator (sftR), an oxygenolytic alkylsulphatase (atsK), an arylsulphotransferase (astA) and a putative TonB-dependent receptor (sftP). The SftP protein was localized in the outer membrane, and the arylsulfphotransferase was identified as an intracellular enzyme. Expression of sftR was repressed in the presence of inorganic sulphate, and the sftR gene was required for the expression of atsBC, atsRK and sftP-astA. An sftR mutant was unable to grow with aryl- or alkylsulphate esters in laboratory media and showed significantly reduced survival compared with the parent strain during incubation in Danish agricultural and grassland soils. This effect suggests that sulphate esters are an important sulphur source for microbes in aerobic soils and highlights the importance of the microbial population in the soil sulphur cycle.
Symbol-by-symbol MAP demodulation of CPM and PSK signals on Rayleigh flat-fading channels (1997)

Demodulation using the symbol-by-symbol maximum a posteriori probability (MAP) algorithm is presented. The algorithm is derived for the case of continuous phase modulation (CPM) signals transmitted over Rayleigh flat-fading channels, and a corresponding receiver structure is specified. It is shown that the MAP algorithm requires computing, for each trellis branch, the sum of the products of the weights of all paths through the trellis which pass through that branch, and that this generic computational problem can be solved efficiently by an approach that uses a forward and backward recursion through the trellis. Simulation results are presented which show both the hard and soft decision performance of the MAP receiver to be robust, even in the presence of fade rates of up to 30% of the symbol rate. The application of the receiver concept to phase-shift keying (PSK) signals is also discussed, and then evaluated via simulation. The concept of joint demodulation and decoding using iterative processing techniques is introduced. It is shown that the MAP receiver is well suited for iterative processing applications due to its use of a priori symbol probabilities and its production of optimal soft decisions. Simulation results for the reception of quaternary PSK (QPSK) show that the bit error rate (BER) performance of the iterative MAP receiver can approach that of a receiver operating with perfect knowledge of the fading process.
Revival of TE2A; a better chelate for Cu(II) ions than TETA? (2010)

A highly effective synthetic route for TE2A was developed and the (64)Cu-labeled TE2A complexes showed higher kinetic inertness and faster clearance than most commonly used TETA analogs.
A 0.037mm2 1GSps 12b self-calibrated 40nm CMOS DAC cell with SFDR>60dB up to 200MHz and IM3 < —60dB up to 350MHz (2020)

This paper presents a very small area 12b IGSps self-calibrated current-steering DAC cell occupying just 0.037mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> in 40nm, while delivering SFDR>60dB up to 200MHz and IM3<; -60dB up to 350MHz. The DAC architecture, selfcalibration apparatus and layout are specifically designed as a balance between small area, robustness, and high performance, so that embedding in VLSI is feasible. The small size of the DAC unit allows massive integration, which is demonstrated in this work by an array of 16 12b DAC units.
Comparison of four arc welding processes used for aluminium alloy cladding (2014)

Metal inert gas (MIG), pulsed MIG, cold metal transfer MIG (CMT) and tungsten inert gas (TIG) welding processes were employed to produce clads. The cladding operations were analysed by an infrared thermal imaging technique and beads were characterised by X-ray radiography, neutron diffraction and microhardness mapping. Surprisingly, the CMT process produces the highest temperatures, but also the highest cooling rate. The MIG processes produce more residual stress and defect than TIG process.
Charging of MgO (2002)

MgO has been well known as a material with high secondary electron yield. The escape depth of electrons for MgO with the ordered structure is relatively large, therefore the electrons are usually re-emitted from bulk MgO. In addition, when the electrons are injected deep into a perfect MgO crystal, polarons are formed, because the electrons have polarized its surroundings. When the density of the polaron sites is high enough, a narrow energy band is established. In the space charge physics, such a band in perfect crystal MgO has been predicted to have a very low barrier between adjacent sites, thus the polarons in the crystal are usually free to move or hop. Any excess electrons will eventually escape to the surface and later they will be neutralized by positive ions or removed by air molecules. Therefore, the material is normally positively charged under electron beam bombardment. In this report, we will verify this proposal in the space charge physics by the well-known mirror method experiment.
HDD Reader Technology Roadmap to an Areal Density of 4 Tbpsi and Beyond (2021)

Massive data growth is accelerating the need for storage. Hard disk drive read/write technology continues to advance to support this demand. This Advanced Storage Research Consortium report combines a top-down (system) and bottom-up (micromagnetic) approach to define a reader technology roadmap for 2.4, 4.0, and 6.0 terabits per square inch (Tbpsi) including dimensional and performance targets. We examine the resolution, SNR, stability and manufacturing requirements, challenges, and gaps. We show that the extension of today&#x2019;s spin valve-based reader designs may enable 4 Tbpsi, but significant gaps must be closed. For higher areal densities, we review future reader designs, challenges, and discuss potential solution paths.
Immunological and chemical studies ofSalmonella haarlemsomatic antigen epitopes. I. Structural studies of O-antigen (1998)

Lipopolysaccharide (LPS) of Salmonella haarlem was hydrolyzed and the products separated. The structure of the O-specific polysaccharide (OPS) was found from sugar and methylation analyses. Rhamnose, mannose, galactose and tyvelose were detected and their linkage modes were established. The structure was confirmed by 1H, homonuclear and heteronuclear correlations and 13C NMR spectra. Anomeric configurations were assigned by chromium trioxide oxidation and proton coupled 13C spectra. Sugar sequence was established from specific carbon shift data and nuclear Overhauser effect spectroscopy. The repeating unit structure of S. haarlem OPS as --> 3)-alpha-D-Galp-(1 --> 6)-[alpha-Tyvp-(1 --> 3)]-beta-D-Manp-(1 --> 4)-alpha-L-Rhap was estimated. No structural heterogeneity of the antigen was found.
New Associate Editor (2023)

It is with great pleasure that I welcome Neale Dutton to the editorial board of IEEE Journal of Solid- State Circuits as a new Associate Editor. Dr. Dutton is an expert on CMOS image sensors.
Coronakrisen har förstärkt personfixeringen inom politiken (2020)

Coronakrisen har gynnat regeringspartier i olika lander. Och valjarens fortroende for partiet ar kopplat till vem som leder partiet - en tendens som forstarkts under Corona. I Norden brukar partiet ...
Generalized Interval Projection: A New Technique for Consistent Domain Extension (2007)

International audience
Viscosity of pure hydrocarbons (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTViscosity of pure hydrocarbonsBoerge Knapstad, Per A. Skjoelsvik, and Harald A. OeyeCite this: J. Chem. Eng. Data 1989, 34, 1, 37–43Publication Date (Print):January 1, 1989Publication History Published online1 May 2002Published inissue 1 January 1989https://pubs.acs.org/doi/10.1021/je00055a013https://doi.org/10.1021/je00055a013research-articleACS PublicationsRequest reuse permissionsArticle Views1010Altmetric-Citations110LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts