gebhart/patrepeval huggingface dataset:
Phenylcyclohexylcarbinols with Antispasmodic Activity1 (1956)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhenylcyclohexylcarbinols with Antispasmodic Activity1M. Harfenist and E. MagnienCite this: J. Am. Chem. Soc. 1956, 78, 5, 1060–1064Publication Date (Print):March 1, 1956Publication History Published online1 May 2002Published inissue 1 March 1956https://doi.org/10.1021/ja01586a049RIGHTS & PERMISSIONSArticle Views145Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (655 KB) Get e-Alerts Get e-Alerts
Learned harmonic mean estimation of the marginal likelihood with normalizing flows (2023)

Computing the marginal likelihood (also called the Bayesian model evidence) is an important task in Bayesian model selection, providing a principled quantitative way to compare models. The learned harmonic mean estimator solves the exploding variance problem of the original harmonic mean estimation of the marginal likelihood. The learned harmonic mean estimator learns an importance sampling target distribution that approximates the optimal distribution. While the approximation need not be highly accurate, it is critical that the probability mass of the learned distribution is contained within the posterior in order to avoid the exploding variance problem. In previous work a bespoke optimization problem is introduced when training models in order to ensure this property is satisfied. In the current article we introduce the use of normalizing flows to represent the importance sampling target distribution. A flow-based model is trained on samples from the posterior by maximum likelihood estimation. Then, the probability density of the flow is concentrated by lowering the variance of the base distribution, i.e. by lowering its "temperature", ensuring its probability mass is contained within the posterior. This approach avoids the need for a bespoke optimisation problem and careful fine tuning of parameters, resulting in a more robust method. Moreover, the use of normalizing flows has the potential to scale to high dimensional settings. We present preliminary experiments demonstrating the effectiveness of the use of flows for the learned harmonic mean estimator. The harmonic code implementing the learned harmonic mean, which is publicly available, has been updated to now support normalizing flows.
Multiple Hydrogen Transfers in Enzyme Action (2006)

This chapter contains sections titled: Introduction Cofactor-Dependent with Activated Substrates Alanine Racemase Broad Specificity Amino Acid Racemase Serine Racemase Mandelate Racemase ATP-Dependent Racemases Methylmalonyl-CoA Epimerase Cofactor-Dependent with Unactivated Substrates Cofactor-Independent with Activated Substrates Proline Racemase Glutamate Racemase DAP Epimerase Sugar Epimerases Cofactor-Independent with Unactivated Substrates Summary References
Transforming Growth Factor β<sub>2</sub> Increases in Subretinal Fluid in Rhegmatogenous Retinal Detachment with Subretinal Strands (2005)

The concentrations of total and mature TGF-beta(2) were higher in cases of rhegmatogenous retinal detachment associated with subretinal strand formation compared to those without subretinal strand formation.
Hydrogen Storage in Nanostructured Carbon Materials at Room Temperature (2002)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Xiaohong Chen, Urszula Dettlaff‐Weglikowska, Miro Haluska, Michael Hirscher, Marion Becher, Siegmar Roth; Hydrogen Storage in Nanostructured Carbon Materials at Room Temperature. AIP Conf. Proc. 14 October 2002; 633 (1): 597–600. https://doi.org/10.1063/1.1514191 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
Dual-Band Coil Module With Repeaters for Diverse Wireless Power Transfer Applications (2017)

Dual-band coil modules facilitate efficient access to distinct-band, high-power, or rapid-charging wireless power transfer (WPT) systems. However, they do not function efficiently when the frequency ratio between two operating frequencies is large. To overcome this problem, we propose enhanced dual-band coil modules that adopt repeaters in the WPT system. We present a circuit-based analysis of repeaters in various dual-band coil modules compared with those in a single-band WPT system. The analytical results provide a design methodology applicable to diverse types of dual-band coil modules with a repeater in the WPT system. Our experimental results are consistent with the circuit-based analysis: coil power transfer efficiencies of 55% at 200 kHz and 74% at 6.78 MHz were obtained concurrently in the dual-band WPT system with a dual-band repeater. This paper reduced the application constraint of dual-band coil modules and facilitated the realization and application of multiband WPT systems.
Behavioral development and olfactory learning in the honeybee Apis mellifera (1999)

Honeybees (Apis mellifera) can be readily conditioned in the laboratory to specific odors paired with a subsequent sucrose reward. A series of experiments are reported which demonstrate that the ability of bees to acquire and retain this learning is affected by the stage of behavioral development (caste). Results show rapid acquisition of the proboscis extension reflex (PER) conditioning in adult forager bees, however much slower acquisition and poorer retention of the same learning paradigm in younger adults, i.e., nurse bees and guard bees. Further, if nurse bees are made to forage precocially by manipulation of the hive population, these bees show excellent acquisition and retention of PER conditioning comparable to normal adult forager bees. Results are discussed in terms of olfactory learning requirements of bees performing caste-specific behaviors and the maturation of the bee nervous system. © 1999 John Wiley & Sons, Inc. Dev Psychobiol 34: 21–27, 1999
Lot sizing models with backlog or out-sourcing (2005)

This work addresses a single item capacitated dynamic lot sizing problem. We consider backlogging models as well as out-sourcing models to minimize the total cost. The production, holding and backlogging or out-sourcing cost functions considered in This work are arbitrary and time-varying. Due to various capacity constraints, it is possible that no feasible solution exists. We give a necessary and sufficient condition for there to be a feasible solution and show that this condition can be checked in polynomial time. When feasible solutions exist, we show that an optimal solution can be obtained in pseudo-polynomial time with dynamic programming algorithms. We then address polynomially solvable special cases of stockout and conservation models.
Gas-Phase Formation of Highly Luminescent 2D GaSe Nanoparticle Ensembles in a Nonequilibrium Laser Ablation Process (2020)

Interest in layered two-dimensional (2D) materials has been escalating rapidly over the past few decades due to their promising optoelectronic and photonic properties emerging from their atomically thin 2D structural confinements. When these 2D materials are further confined in lateral dimensions toward zero-dimensional (0D) structures, 2D nanoparticles and quantum dots with new properties can be formed. Here, we report a nonequilibrium gas-phase synthesis method for the stoichiometric formation of gallium selenide (GaSe) nanoparticles ensembles that can potentially serve as quantum dots. We show that the laser ablation of a target in an argon background gas condenses the laser-generated plume, resulting in the formation of metastable nanoparticles in the gas phase. The deposition of these nanoparticles onto the substrate results in the formation of nanoparticle ensembles, which are then post-processed to crystallize or sinter the nanoparticles. The effects of background gas pressures, in addition to crystallization/sintering temperatures, are systematically studied. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), photoluminescence (PL) spectroscopy, and time-correlated single-photon counting (TCSPC) measurements are used to study the correlations between growth parameters, morphology, and optical properties of the fabricated 2D nanoparticle ensembles.
A control method for stable and smooth path following of mobile robots (2005)

This paper addresses the problem of mobile robot navigation in indoor cluttered environments. A new algorithm for both longitudinal and lateral real-time control of wheel-based mobile robots has been proposed. Its main characteristic is smooth and stable following of the on-line replanned path. Our control method is actually extension of the virtual vehicle method proposed by M. Egerstedt et al., which is based on the introduction of a look-ahead point on the path that serves as reference point for the control algorithm. While the original virtual vehicle method uses only error feedback for reference point movement along the path, our method uses also a feedforward component based on path curve characteristics between the robot and the reference point. In this way stable robot movement is achieved also in the presence of obstacles that are critical with respect to the path following error. Experimental verification is provided for a differential drive robot within an on-line global path planning framework.
Chiral Mesoporous Materials Based on the Self-Assembly (2006)

Ordered mesoporous materials with various structures are synthesized based on the self-assembly of surfactant and inorganic precursors and covered by several excellent reviews. However, less work has been directed to chiral structured mesoporous materials, although these could have wide-ranging applications on the manufacturing of enantio-pure chemicals and pharmaceuticals as catalysts and separation media with both shape selectivity and enantioselectivity. This short review will address the synthesis of chiral mesoporous materials by chiral organic compounds templating route, covering single and 2-dimensional ordered chiral channel mesoporous materials. Non-porous helical fiber, atomic-scale enantio-morphism and zeolite-like materials with three-dimensional helical pores are beyond the scope of this paper.
Microbial adhesion capacity. Influence of shear and temperature stress (2015)

Environmental parameters dictate the conditions for both biofilm formation and deconstruction. The aim of this study is to analyse the impact of hydrodynamic and thermodynamic effects on bacterial detachment. Escherichia coli grown on two stainless steel metal surfaces with different roughness (brushed with roughness of 0.05 μm and electropolished with roughness of 0.29 μm) are exposed to laminar and turbulent (shower) flows of phosphate buffered saline media at temperatures of 8, 20 and 37 °C. Results show that the turbulent flow removes significantly more bacterial cells than laminar flow (p <0.05) on both materials. This indicates that the shear force determines the rate of detached bacteria. It is also observed that detachment of cells is more efficient on brushed than on electropolished contact surfaces because on the latter surface, fewer cells were attached before exposure. Moreover, we demonstrate that the temperature of the washing agent has an impact on bacterial detachment. At the same flow conditions, the exposure to higher temperature results in greater detachment rate.
Oligoclonal expansion of CD8+ CD57+ T cells with restricted T-cell receptor beta chain variability after bone marrow transplantation (1994)

A major expansion of CD8+57+ lymphocytes expressing an alpha-beta T- cell receptor (TCR) is frequent after bone marrow transplantation (BMT). We examined the clonality of the TCR beta gene repertoire in these expanded CD8+57+ cells after allogeneic or autologous BMT. We performed a polymerase chain reaction (PCR) analysis of the V beta chain usage in CD8+57+ cells purified from nine BMT recipients with a series of oligonucleotides specific for 20 V beta gene families. PCR products from selected TCR beta gene rearrangements were sequenced. The CD8+57+ cells from eight of nine patients used a restricted set of V beta families, with a marked predominance of two to three V beta gene families per patient, whereas the control autologous CD57- subset expressed the whole 20 V beta families. A direct sequencing analysis confirmed the V beta 16 and V beta 17 clonality in six patients, showing a striking homology in the CDR3 sequences of the V beta 16 products. The CD8+57+ cells, but not the CD57- cells, displayed an oligoclonal pattern of TCR rearrangements as shown by PCR analysis of TCR gamma gene rearrangements. Such an oligoclonal expansion of CD8+57+ cells, using a restricted set of the V beta gene families, may result from a specific TCR stimulation of a limited number of T-cell clones in BMT recipients.
Dual Inhibition of Hedgehog and c-Met Pathways for Pancreatic Cancer Treatment (2017)

Pancreatic ductal adenocarcinoma (PDAC) is one of the most chemotherapy- and radiotherapy-resistant tumors. The c-Met and Hedgehog (Hh) pathways have been shown previously by our group to be key regulatory pathways in the primary tumor growth and metastases formation. Targeting both the HGF/c-Met and Hh pathways has shown promising results in preclinical studies; however, the benefits were not readily translated into clinical trials with PDAC patients. In this study, utilizing mouse models of PDAC, we showed that inhibition of either HGF/c-Met or Hh pathways sensitize the PDAC tumors to gemcitabine, resulting in decreased primary tumor volume as well as significant reduction of metastatic tumor burden. However, prolonged treatment of single HGF/c-Met or Hh inhibitor leads to resistance to these single inhibitors, likely because the single c-Met treatment leads to enhanced expression of Shh, and vice versa. Targeting both the HGF/c-Met and Hh pathways simultaneously overcame the resistance to the single-inhibitor treatment and led to a more potent antitumor effect in combination with the chemotherapy treatment. <i>Mol Cancer Ther; 16(11); 2399-409. ©2017 AACR</i>.
Enhanced THz emission from spintronic Fe/Pt emitters through crystal growth optimization (2020)

We investigate the THz emission characteristics of ferromagnetic/non-magnetic metallic heterostructures, focusing on thin Fe/Pt bilayers. In particular, we report on the impact of optimized crystal growth of the epitaxial Fe layers on the THz emission amplitude and spectral bandwidth. We demonstrate an enhancement of the emitted intensity along with an expansion of the emission bandwidth. Both are related to reduced spin scattering and higher interface transmission. Our work provides a pathway for devicing optimal spintronic THz emitters based on epitaxial Fe. It also highlights how THz emission measurements can be utilized to characterize the changes in out-of-equilibrium spin current dynamics in metallic heterostructures, driven by subtle structural refinement.
Development of a New Finite Element Model for the BioRID II Crash Dummy (2008)

&lt;div class="htmlview paragraph"&gt;The BioRID-II (Biofidelic Rear Impact Dummy) has been developed as a testing tool to measure automotive seat and head restraint system performance in low-speed rear end crashes and to help with understanding of whiplash neck injuries. The present paper focuses on the current Abaqus BioRID-II model which has been developed by Dassault Systemes Simulia Corp. (SIMULIA) in cooperation with the German Association for Research in Automobile Technology FAT, utilizing an extensive suite of material, component and full dummy experiments in the universal Chalmers seat in order to calibrate and validate the model response. The Abaqus BioRID-II model uses connector elements extensively to model complex connections and instrumentation, and to help improve runtime efficiency by reducing the number of degrees of freedom in the model. The assembly process for the actual BioRID-II dummy introduces nontrivial initial deformations and stresses in the critical components of the neck and spine, which must be accounted for in the model itself; the Abaqus BioRID-II model leverages both the explicit and the implicit solution techniques available in the Abaqus product suite to accomplish this. Finally, a comparison between Abaqus simulation results against available experimental test data is included in the paper, suggesting the usefulness of the model in evaluating dummy response and seat performance. Although the responses of most of the variables monitored in the Abaqus dummy are matching well the experimental responses, the authors would like to underline that this paper presents the current development status of this dummy and that there is an ongoing effort to improve its quality.&lt;/div&gt;
Effects of Succinonitrile (SN) as an Electrolyte Additive on the Impedance of LiCoO2/Graphite Pouch Cells during Cycling (2014)

LiCoO2/graphite pouch cells with 1.0M LiPF6 in EC:DEC (1:2 v/v) electrolyte were used to study the effect of succinonitrile (SN) as an electrolyte additive on the cell impedance during cycling. Pouch cells containing no additives, 2 wt% vinylene carbonate (VC), 2 wt% SN and 2 wt% VC + 2 wt% SN were studied for comparison. In order to investigate which electrode contributed to impedance changes during charge and discharge cycling, positive and negative electrode symmetric cells, fabricated using electrodes extracted from the parent pouch cells, were studied using electrochemical impedance spectroscopy (EIS). Two wt% VC added to the electrolyte suppressed impedance growth of the positive electrode during cycling, while the addition of 2 wt% SN greatly increased the impedance growth of the positive electrode during cycling. The addition of both 2 wt% VC and 2 wt% SN leads to intermediate behavior. In all cases, the negative electrode impedance decreased during cycling when VC, SN or VC+SN additives were present. The dominant contribution to the impedance growth of pouch cells containing SN during cycling comes from the positive electrode.
Penile Skin Flaps for Urethral Reconstruction (2008)

The penile skin flap is a versatile tool in the reconstruction of anterior urethral stricture disease. When adequate non-diseased skin exists and when the arterial supply is dependable, a flap may be used for single stage reconstruction of strictures from the bulbar urethra to the urethral meatus. The surgical technique is challenging; a thorough understanding of the penile anatomy, particularly the vascular anatomy and fascial layers, is necessary to successful flap harvest. While based on similar principles, the various penile skin flaps described in this chapter have distinct differences in their technique of harvest as well as their appropriateness for strictures of the bulbar and penile urethra. All share a common blood supply in the external pudendal arteries. All involve the isolation of an island of skin dependent on this vascular pedicle. The differences in technique center on whether the island is isolated transversely or longitudinally, to what degree the pedicle is developed proximally and whether the pedicle is primarily ventrally-based or dorsally-based. With a proper understanding of each of these techniques a surgeon is well-prepared to approach the difficult task of anterior urethral reconstruction.
Open Rotor Noise Shielding by Blended-Wing-Body Aircraft (2015)

This paper presents an analysis of open rotor noise shielding by Blended Wing Body (BWB) aircraft by using model scale test data acquired in the Boeing Low Speed Aeroacoustic Facility (LSAF) with a legacy F7/A7 rotor model and a simplified BWB platform. The objective of the analysis is the understanding of the shielding features of the BWB and the method of application of the shielding data for noise studies of BWB aircraft with open rotor propulsion. By studying the directivity patterns of individual tones, it is shown that though the tonal energy distribution and the spectral content of the wind tunnel test model, and thus its total noise, may differ from those of more advanced rotor designs, the individual tones follow directivity patterns that characterize far field radiations of modern open rotors, ensuring the validity of the use of this shielding data. Thus, open rotor tonal noise shielding should be categorized into front rotor tones, aft rotor tones and interaction tones, not only because of the different directivities of the three groups of tones, but also due to the differences in their source locations and coherence features, which make the respective shielding characteristics of the three groups of tones distinctly different from each other. To reveal the parametric trends of the BWB shielding effects, results are presented with variations in frequency, far field emission angle, rotor operational condition, engine installation geometry, and local airframe features. These results prepare the way for the development of parametric models for the shielding effects in prediction tools.
Original article Lipid degradation and sensory characteristics of M. biceps femoris in dry-cured hams from Duroc using three different processing methods (2014)

Summary Hams from Norwegian Duroc pigs, reared and fed identically, were dry-cured using three diﬀerent pro-cessing methods: Spanish Serrano (SS), Norwegian Parma-style (PS) and deboning before curing (ND).The fatty acid compositions of the green and dry-cured hams were analysed in terms of their neutral lipid,phospholipid and free fatty acid contents and correlated with sensory attributes. Although the three dry-curing processes were quite diﬀerent, the hams 0 lipid proﬁles, lipid degradation patterns and lipid-associ-ated sensorial characteristics diﬀered only slightly. The phospholipids were the most extensively degradedlipid class (88, 89% and 84% degradation in PS, SS and ND hams, respectively) for all processing meth-ods. The SS and PS hams had slightly riper sensory proﬁles due to their extensive conversion of fattyacids into aroma components. The free fatty acid contents of PS, SS and ND hams were 6.3, 6.2 and 7.5times greater than those of green hams, respectively.Keywords Dry-cured ham, fatty acid proﬁle, lipid oxidation, lipolysis, processing method, sensory proﬁle.
Constituents of Scaevola frutescens (MILLER) KRAUSE (1974)

Constituents of Scaevola frutescens (MIILER) KRAUSE were investigated and several known triterpenes and xanthyletin (VIII) were obtained. In addition, two kinds of coumarins (IX and XI) were isolated and their structures were examined by means of nuclear magnetic double resonance methods.
Challenges in Designing Fibers and Operating High Power CW and Pulsed Fiber Lasers (2014)

Challenges in design of high power CW and pulsed fiber lasers for commercial applications are reviewed, when output in excess of one hundred lasers per week is required.