gebhart/patrepeval huggingface dataset:
B Complex Vitamins in Sugar Cane and Sugar Cane Juice (1944)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTB Complex Vitamins in Sugar Cane and Sugar Cane JuiceWilliam R. Jackson and Thomas J. MacekCite this: Ind. Eng. Chem. 1944, 36, 3, 261–263Publication Date (Print):March 1, 1944Publication History Published online1 May 2002Published inissue 1 March 1944https://pubs.acs.org/doi/10.1021/ie50411a017https://doi.org/10.1021/ie50411a017research-articleACS PublicationsRequest reuse permissionsArticle Views53Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Sensors with Langmuir-Blodgett films. (1989)

Chemical sensors using Langmuir-Blodgett (LB) films have been reviewed. After chemical sensors are classified according to the types of transducing devices and the kinds of analytes in gas or liquid, the sensors with LB films already reported are described. Subsequently, gas sensors, biosensors, and odor sensors are discussed on their materials, deposition conditions and resultant characteristics, etc. The detailed descriptions have been given to the glucose sensors with glucose-oxidaseimmobilized LB films, and it is demonstrated that partially decoiled enzyme molecules can be more efficiently and stably adsorbed onto the monolayer, and more suitable for biosensor fabrication than non-denatured molecules.
BlotGlycoABC™, an Integrated Glycoblotting Technique for Rapid and Large Scale Clinical Glycomics (2007)

Recent progress in mass spectrometry has led to new challenges in glycomics, including the development of rapid glycan enrichment techniques. A facile technique for exploration of a carbohydrate-related biomarker is important because proteomics research targets glycosylation, a posttranslational modification. Here we report an "all-in-one" protocol for high throughput clinical glycomics. This new technique integrates glycoblotting-based glycan enrichment onto the BlotGlycoABC bead, on-bead stabilization of sialic acids, and fluorescent labeling of oligosaccharides in a single workflow on a multiwell filter plate. The advantage of this protocol and MALDI-TOF MS was demonstrated through differentiation of serum N-glycan profiles of subjects with congenital disorders of glycosylation and hepatocellular carcinoma and healthy donors. The method also permitted total cellular glycomics analysis of human prostate cancer cells and normal human prostate epithelial cells. These results demonstrate the potentials of glycan enrichment/processing for biomarker discovery.
Overview of biomedical image analysis (2014)

Image analysis is a vibrant field in research, applications, and technologies. Any image is a representation of data gathered by sensors from a physical environment. Biomedical image analysis deals with biological systems; this book focuses on analysis of images that describe the structure or function of the human body. Broadly speaking, biomedical image analysis includes three major components: segmentation, registration, and visualization. Each of these components is a science and art in its own right, with considerable literature spanning over four decades of theory, algorithms, and applications. Each component has been documented in books, conference proceedings, archived journals, technologies, and commercial products.
The effect of the fastener of different configuration composite panels on failure analysis (2009)

This study presents the effect of the stacking sequence and fiber orientation on a composite sandwich panel subjected to static in-plane bolt loading. Six plates were constructed with laminates of unidirectional carbon fiber and cross ply weaves of fiberglass. The orientations that were examined included 0, +/- 45, and 90 degrees. Half of the plates had fiberglass lamina on the outside of the laminate while the other three plates had the carbon fiber on the outside. Experimental and analytical tests were performed to determine the best orientations and stacking sequence. For the numerical analysis, plates with fibers oriented at +/- 45 degrees showed the highest strength. The experimental data also showed high strengths for the +/- 45 degree plates. However the experimental data also showed high strengths for the 90 degree laminate but with very high displacements. These high displacements would not allow the joint to maintain its relative position to the adjacent part. The discrepancy between the strength of the FEA models and the experimental data is attributed to inaccurate strength properties. The effect of in situ strength and compression strength was found to have a significant effect on the accuracy of the FEA solution. Good correlation was found between the FEA and experimental data in predicting the trend of the stiffness of the plates.
Characteristics of Centrifugal Partition Chromatography for Lanthanoid Separation in Hdehp Extraction System (1994)

Abstract Separation of light lanthanoids with centrifugal partition chromatography (CPC) was investigated in extraction system of 30% HDEHP/CCl4/n-paraffin and HNO3. Since separation factors between lanthanoids, Ce, Nd, Pr, Sm, Eu and Gd, were independent of volume ratio of CCl4 and n-paraffin diluents, difference in the density between the mobile phase and the stationary phase was controlled by varying the volume ratio of two diluents in order to operate at reasonable pump-pressure. The effects of volume of the stationary phase and rotational speed on the separation characteristics of CPC were examined to find the optimum operation conditions. The effect of chain length of n-paraffin (number of carbon atoms: 6 15) as diluents was also examined. The best separation efficiency was obtained with the longest, n-pentadecane. On the basis of the above results, mutual separation of lanthanoids was successfully performed in 30% HDEHP/15% CCl4/55% n-pentadecanc and 0.5 mol/dm3 HNO3 extraction system at a low pump pressure of 4.5 kgf/cm2.
Field testing of an instrument to measure near-surface currents from offshore platforms (2003)

We have carried out extensive field testing of an Acoustic Doppler Current Profiler (ADCP) designed to measure surface currents at ranges of 200-300 m by profiling horizontally from its mounting. The range of vertically profiling ADCPs is well documented, but horizontal profiling from offshore platforms presents unique, less well-understood factors influencing profiling range. These include the potential for interference from other sources on the platform, and that the concentration of scatterers (typically zooplankton) is now relatively uniform over the profiling range. A 300 kHz Horizontal ADCP (H-ADCP), specifically designed with large transducers for maximum range, was deployed from an operating drill ship in the Gulf of Mexico with a stated goal of characterizing its profiling range under varying conditions. The maximum range was determined under a number of possible configurations, which included varying the cell size, bandwidth and mounting depth. The H-ADCP presents a unique, simple means for obtaining continuous, real-time horizontal profiles of the near surface currents at significant ranges from an offshore platform. These near surface measurements can not be made with a conventional vertical ADCP due to interference from the platform and its thrusters. We here present a brief review of the measurement technique followed by a description of the tests performed during the trial. We then present the results from systematic testing intended specifically to empirically characterize the performance of this instrument from an offshore platform.
KEY ISSUES IN BILINGUALISM AND BILINGUAL EDUCATION. Colin Baker. Clevedon, England: Multilingual matters, 1988. Pp.x + 222. (1990)

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
P-1034 - Effects of perinatal exposure to connexin43 antibodies on the cognitive function in rats (2012)

Connexin43 (Cx43) is the main protein of brain astrocytic gap-junctional network, which plays an important role in the ion and glutamate homeostasis, intercellular signaling, cell adhesion and migration during brain morphogenesis. Earlier we obtained monoclonal antibodies to the E2 extracellular loop of Cx43 (MAbE2Cx43) which could block the functions of astrocytic gap-junctions in vitro and in vivo. The aim of the current study was to elucidate the influence of MAbE2Cx43 on the cognitive function in animals treated during neurogenesis. The antibodies were injected intravenously to wild pregnant female rats in a dose of 5 mg/kg on the 10thday of gestation. The saline solution was used as a control medicine. Behavioral experiments were conducted on 1-month old offsprings in the following order: the Y-maze, novel object recognition test (NORT) and passive avoidance (PA) task. The Y-maze test revealed a significant decrease in the spontaneous alternation behavior of experimental rats treated with MAbE2Cx43 in the perinatal period compared to control rats. In the NORT rats treated with MAbE2Cx43 have shown significant impairments of the recognition memory after a 24-hour delay. The PA test revealed no significant difference in avoidance latency in the retention trial on the day 2-nd, but it appeared on the day 7-th. These findings confirm memory deficiency after one-time administration of MAbE2Cx43 in the perinatal period. We conclude that the injection of anti-Cx43 antibodies in the perinatal period could alter some Cx43-dependent processes during neurogenesis resulting in cognitive deficiency in adulthood.
Null-space impedance control with disturbance observer (2012)

In this paper a new approach for the null-space impedance control of a kinematically redundant robot is proposed. The approach is useful for the case where the robot experience an external interaction on the body, especially in the presence of humans. The proposed algorithm guarantees safe and dependable physical interaction of the robot body with the environment, thanks to the null-space impedance control. At the same time, the correct execution of the task assigned to the end effector is ensured by a disturbance observer. The algorithm does not require joint torque measurements. The performance of the proposed controller is verified through simulations on 7R KUKA lightweight robot arm.
Immunolocalization of Dpfp1, a Byssal Protein of the Zebra Mussel Dreissena Polymorpha (2000)

The zebra mussel is one of only a few freshwater bivalves known to produce a byssus. This fibrous, proteinaceous and highly cross-linked structure allows the mussel to attach to a variety of substrata and contributes to its notoriety as a major freshwater biofouling species. We have successfully expressed a full-length version of Dreissena polymorpha foot protein 1 (Dpfp1), a putative byssal thread precursor, and have used the recombinant protein as an antigen for polyclonal antibody production. Antisera obtained from rabbits immunized with recombinant Dpfp1 recognize the protein in western blots of extracts from foot tissue and byssal threads. On the basis of this evidence, we conclude that Dpfp1 is a byssal precursor protein manufactured and stored in the foot of the mussel. Immunohistochemical localization of Dpfp1 suggests that the protein is localized in secretory granules in a large gland surrounding the ventral groove of the foot. Only a subset of these glandular cells stockpiles the protein, implying that the zebra mussel foot is a complex organ capable of several distinct secretory activities involved in byssal thread formation. The uniform distribution of Dpfp1-containing cells suggests that the protein is a significant load-bearing component of zebra mussel byssal threads, although a more rigorous test of this hypothesis awaits ultrastructural localization of the protein in mature byssal threads.
Active Site Substitution A82W Improves the Regioselectivity of Steroid Hydroxylation by Cytochrome P450 BM3 Mutants As Rationalized by Spin Relaxation Nuclear Magnetic Resonance Studies (2011)

Cytochrome P450 BM3 from Bacillus megaterium is a monooxygenase with great potential for biotechnological applications. In this paper, we present engineered drug-metabolizing P450 BM3 mutants as a novel tool for regioselective hydroxylation of steroids at position 16β. In particular, we show that by replacing alanine at position 82 with a tryptophan in P450 BM3 mutants M01 and M11, the selectivity toward 16β-hydroxylation for both testosterone and norethisterone was strongly increased. The A82W mutation led to a ≤42-fold increase in V(max) for 16β-hydroxylation of these steroids. Moreover, this mutation improves the coupling efficiency of the enzyme, which might be explained by a more efficient exclusion of water from the active site. The substrate affinity for testosterone increased at least 9-fold in M11 with tryptophan at position 82. A change in the orientation of testosterone in the M11 A82W mutant as compared to the orientation in M11 was observed by T(1) paramagnetic relaxation nuclear magnetic resonance. Testosterone is oriented in M11 with both the A- and D-ring protons closest to the heme iron. Substituting alanine at position 82 with tryptophan results in increased A-ring proton-iron distances, consistent with the relative decrease in the level of A-ring hydroxylation at position 2β.
160-Gb/s optical networking: a prospective techno-economical analysis (2005)

This paper reports on a network dimensioning analysis of N /spl times/ 160-Gb/s wavelength-division-multiplexed (WDM) networks based on the optical time-division-multiplexing (OTDM) technique. The need for different transmission and networking functions based on innovative circuit-switched scenarios for optical core networks is quantified, and the economical interest of such high-wavelength channel bit rates in the chosen scenarios is evaluated.
Structural Determinants of AMPA Agonist Activity in Analogues of 2-Amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic Acid:  Synthesis and Pharmacology (2000)

We have previously shown that the 2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor agonist, 2-amino-3-(3-carboxy-5-methyl-4-isoxazolyl)propionic acid (ACPA, 2), binds to AMPA receptors in a manner different from that of AMPA (1) itself and that 2, in contrast to 1, also binds to kainic acid receptor sites. To elucidate the structural requirements for selective activation of the site/conformation of AMPA receptors recognized by 2, a number of isosteric analogues of 2 have now been synthesized and pharmacologically characterized. The compound 2-amino-3-(5-carboxy-3-methoxy-4-isoxazolyl)propionic acid (3a) (IC(50) = 0.11 microM; EC(50) = 1.2 microM), which is a regioisostere of 2 with a methoxy group substituted for the methyl group, was approximately equipotent with 2 (IC(50) = 0.020 microM; EC(50) = 1.0 microM) as an inhibitor of [(3)H]AMPA binding and as an AMPA agonist, respectively, whereas the corresponding 3-ethoxy analogue 3b (IC(50) = 1.0 microM; EC(50) = 4.8 microM) was slightly weaker. The analogues 3c-e, containing C3 alkoxy groups, were an order of magnitude weaker than 3b, whereas the additional steric bulk of the alkoxy groups of 3f-i or the presence of an acidic hydroxyl group at the 3-position of the isoxazole ring of 3j prevented interaction with AMPA receptor sites. The 2-amino-3-(2-alkyl-5-carboxy-3-oxo-4-isoxazolyl)propionic acids 4a,b, i, which are regioisosteric analogues of 3a,b,i, showed negligible interaction with AMPA recognition sites. Similarly, replacement of the carboxyl group of 3b by isosteric tetrazolyl or 1,2,4-triazolyl groups to give 5 and 6, respectively, or conversion of 3b into analogue 7, in which the diaminosquaric acid group has been bioisosterically substituted for the alpha-aminocarboxylic acid unit, provided compounds completely devoid of effect at AMPA receptors. In contrast to the parent compound ACPA (2) (IC(50) = 6.3 microM), none of the analogues described showed detectable inhibitory effect on [(3)H]kainic acid receptor binding.
Measurements of contact specific low-bias negative differential resistance of single metalorganic molecular junctions (2013)

Negative differential resistance (NDR) behaviors of single molecule junctions composed of a thiol-terminated Ru(ii) bis-terpyridine (Ru(tpy-SH)2) molecule sandwiched between two gold electrodes are measured using a specifically modified scanning probe microscope break junction technique (SPMBJ) at room temperature. The low-bias (0.623 ± 0.135 V) NDR observed for one of the three conductance groups is contact specific and is caused by a bias induced electrode-molecule coupling changes.
Effect of Serum on Electrochemical Detection of Bioassays Having Ag Nanoparticle Labels (2021)

The effect of serum on electrochemical detection of bioassays having silver nanoparticle (AgNP) detection labels was investigated. Both a model assay and an antigen-specific sandwich bioassay for the heart failure marker NT-proBNP were examined. In both cases, the AgNP labels were conjugated to a detection antibody. Electrochemical detection was carried out using a galvanic exchange/anodic stripping voltammetry method in which Au<sup>3+</sup> exchanges with AgNP labels. The assays were carried out using a paper-based electrode platform. The bioassays were exposed to different serum conditions prior to and during detection. There are three important outcomes reported in this article. First, both the model- and antigen-specific assays could be formed in undiluted serum with no detectable interferences from the serum components. Second, to achieve the maximum possible electrochemical signal, the highest percentage of serum that can remain in an assay buffer during electrochemical detection is 0.25% when no washing is performed. The assay results are rendered inaccurate when 0.50% or more of serum is present. Third, the factors inhibiting galvanic exchange in serum probably relate to surface adsorption of biomolecules onto the AgNP labels, chelation of Au<sup>3+</sup> by serum components, or both. The results reported here provide general guidance for using metal NP labels for electrochemical assays in biofluids.
ChemInform Abstract: Cancer Chemotherapy: A Paclitaxel Prodrug for ADEPT (Antibody‐Directed Enzyme Prodrug Therapy). (2002)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Re: Verification of Mesenchymal Stem Cell Injection Therapy for Interstitial Cystitis in a Rat Model (2020)

No AccessJournal of UrologyUrological Survey1 Aug 2020Re: Verification of Mesenchymal Stem Cell Injection Therapy for Interstitial Cystitis in a Rat Model Anthony AtalaMD Anthony AtalaAnthony Atala More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000001117.01AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Re: Verification of Mesenchymal Stem Cell Injection Therapy for Interstitial Cystitis in a Rat Model." The Journal of Urology, 204(2), pp. 389–390 Suggested Reading : Prevalence of symptoms of bladder pain syndrome/interstitial cystitis among adult females in the United States. J Urol 2011; 186: 540. Link, Google Scholar : Symptoms of interstitial cystitis, painful bladder syndrome and similar diseases in women: a systematic review. J Urol 2007; 177: 450. Link, Google Scholar : Clinical features and spectrum of light microscopic changes in interstitial cystitis. J Urol 1990; 143: 1118. Link, Google Scholar © 2020 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 204Issue 2August 2020Page: 389-390 Advertisement Copyright & Permissions© 2020 by American Urological Association Education and Research, Inc.MetricsAuthor Information Anthony Atala More articles by this author Expand All Advertisement PDF downloadLoading ...
Isolation and characterization of a beta-D-glucuronidase-producing strain of Escherichia coli serotype O157:H7 in the United States (1995)

A phenotypic variant of Escherichia coli serotype O157:H7 (G5101) was isolated from a patient with bloody diarrhea. Strain G5101 does not ferment sorbitol but is beta-D-glucuronidase and urease positive. Serotyping and colony hybridization using a serotype-specific DNA probe confirmed that the isolate was O157:H7. G5101 produces Shiga-like toxins I and II and contains an eae gene that is highly conserved in the O157:H7 serotype. This strain would have been missed by laboratories that screen for the sorbitol-negative, beta-D-glucuronidase-negative phenotype in isolating E. coli O157:H7 from clinical and food specimens.
Magnetic Bloch theorem and reentrant flat bands in twisted bilayer graphene at 2π flux (2022)

Bloch's theorem is the centerpiece of topological band theory, which itself has defined an era of quantum materials research. However, Bloch's theorem is broken by a perpendicular magnetic field, making it difficult to study topological systems in strong flux. For the first time, moir\'e materials have made this problem experimentally relevant, and its solution is the focus of this paper. We construct gauge-invariant irreps of the magnetic translation group at $2\ensuremath{\pi}$ flux on infinite boundary conditions, allowing us to give analytical expressions in terms of the Siegel theta function for the magnetic Bloch Hamiltonian, non-Abelian Wilson loop, and many-body form factors. We illustrate our formalism using a simple square lattice model and the Bistritzer-MacDonald Hamiltonian of twisted bilayer graphene, obtaining reentrant ground states at $2\ensuremath{\pi}$ flux under the Coulomb interaction.
Wormlike Aggregates from a Supramolecular Coordination Polymer and a Diblock Copolymer (2007)

The formation of wormlike micelles in mixed systems of a supramolecular coordination polymer Zn-L2EO4 and a diblock copolymer P2MVP41-b-PEO205 is investigated by light scattering and Cryo-TEM. By direct mixing at a stoichiometric charge ratio, the above mixtures proved to be capable of formation of spherical micelles with a radius of about 25 nm (Yan et al. Angew. Chem., Int. Ed.; 2007, 46, 1807-1809). Lately, we find wormlike micelles with a hydrodynamic radius >150 nm in a mixture with excess positive charge, that is, a negative charge fraction f- < 0.5. The transformation between wormlike and spherical micelles can be realized by variation of the mixing ratio through different protocols. Upon addition of negatively charged Zn-L2EO4 to a mixture with excess positively charged P2MVP41-b-PEO205, most of the wormlike micelles are transformed into spherical ones; upon addition of positively charged P2MVP41-b-PEO205 to a mixture of pure spherical micelles, wormlike micelles can be produced again. The effect of sample preparation protocol, sample history, and concentration on this transformation process is systematically reported in this article. A possible mechanism for the formation of wormlike micelles is proposed.