gebhart/patrepeval huggingface dataset:
Iterative detection of MIMO signals with linear detectors (2003)

We investigate an iterative receiver structure performing joint symbol detection and decoding to suppress the strong interference in multiple input multiple output (MIMO) systems. A linear minimum mean-squared error (MMSE) detector is compared with a simplified approach. Existing approaches for related scenarios are modified and extended to fit to a generalized MIMO transmitter structure such that the developed detectors are applicable to many known MIMO systems. Simulation results show that the proposed iterative receivers achieve large gains over standard solutions. Interestingly, feeding back the entire a posteriori information from the decoder to the detector outperforms the common approach of feeding back extrinsic information.
Sterile Filtration (2020)

This book focuses on sterilizing grade filters in the biopharmaceutical industry, emphasizing practical applications of universal and dependable operational protocols, integrity testing, and troubleshooting to streamline the production and preparation of pharmaceuticals.Addresses the complexities of globalizing redundancy in filtration! <BR
Analysis of Page Replacement Policies in the Fluid Limit (2010)

The performance of storage systems and database systems depends significantly on the page replacement policies. Although many page replacement policies have been discussed in the literature, their performances are not fully understood. We introduce analytical techniques for evaluating the performances of page replacement policies including two queue (2Q), which manages two buffers to capture both the recency and frequency of requests. We derive an exact expression for the probability that a requested item is found (the hit probability) in a buffer managed by 2Q in the fluid limit, where the number of items is scaled by n, the size of items is scaled by 1/n, and n approaches infinity. The hit probability in the fluid limit approximates the hit probability in the original system, and we find that the relative error in the approximation is typically within 1%. Our analysis also illuminates several fundamental properties of 2Q useful for system designers.
Malignant mesothelioma: Facts, Myths, and Hypotheses (2011)

Malignant mesothelioma (MM) is a neoplasm arising from mesothelial cells lining the pleural, peritoneal, and pericardial cavities. Over 20 million people in the US are at risk of developing MM due to asbestos exposure. MM mortality rates are estimated to increase by 5-10% per year in most industrialized countries until about 2020. The incidence of MM in men has continued to rise during the past 50 years, while the incidence in women appears largely unchanged. It is estimated that about 50-80% of pleural MM in men and 20-30% in women developed in individuals whose history indicates asbestos exposure(s) above that expected from most background settings. While rare for women, about 30% of peritoneal mesothelioma in men has been associated with exposure to asbestos. Erionite is a potent carcinogenic mineral fiber capable of causing both pleural and peritoneal MM. Since erionite is considerably less widespread than asbestos, the number of MM cases associated with erionite exposure is smaller. Asbestos induces DNA alterations mostly by inducing mesothelial cells and reactive macrophages to secrete mutagenic oxygen and nitrogen species. In addition, asbestos carcinogenesis is linked to the chronic inflammatory process caused by the deposition of a sufficient number of asbestos fibers and the consequent release of pro-inflammatory molecules, especially HMGB-1, the master switch that starts the inflammatory process, and TNF-alpha by macrophages and mesothelial cells. Genetic predisposition, radiation exposure and viral infection are co-factors that can alone or together with asbestos and erionite cause MM. J. Cell. Physiol. 227: 44-58, 2012. © 2011 Wiley Periodicals, Inc.
Next‐generation sequencing of HLA‐G based on long‐range polymerase chain reaction (2018)

Clarifying the functional roles of HLA-G and the variation in the HLA-G gene that affects the expression are increasingly important in reproduction, cancer, organ transplantation, and autoimmune diseases. The homology between HLA genes and the genetic variability within each gene complicates the design of HLA gene-specific genotyping assays. We have designed a high-throughput, cost-efficient, robust, and specific assay for sequencing the full HLA-G gene including the 5'-upstream regulatory region, introns, and the 3'-untranslated region, using the next-generation sequencing (NGS) platform Ion Torrent PGM (Thermo Fisher Scientific, Waltham, Massachusetts). Conventional sequencing methods require the design of multiple primer pairs in order to cover the entire HLA-G gene. Designing multiple primer pairs specific for the HLA-G gene that also target all known alleles is difficult. Here, we present a setup that by the use of long-range polymerase chain reaction amplifies the whole HLA-G gene in a single reaction, which only requires a single HLA-G-specific primer pair. Enzymatic DNA shearing is used to break the long-range PCR product into shorter fragments ranging from 75 to 200 bp in length that are sequenced by NGS.
Infantile Epileptic Encephalopathy, Transient Choreoathetotic Movements, and Hypersomnia due to a De Novo Missense Mutation in the SCN2A Gene (2014)

Mutations of the SCN2A gene have originally been described in association with benign familial neonatal-infantile seizures (BFNIS). Recently, single patients with more severe phenotypes and persisting epileptic encephalopathies have been recognized. We report the case of a girl with severe infantile onset epileptic encephalopathy and a de novo missense mutation in the SCN2A gene (c.4025T > C/ = ; p.L1342P/ = ), who presented with a transient choreatic movement disorder, hypersomnia, and progressive brain atrophy. Whole exome sequencing did not reveal any other disease causing mutation. Our patient contributes to the expanding phenotypic spectrum of SCN2A-related disorders and underlines the importance of genetic workup in epileptic encephalopathies.
A Novel Approach to Avoiding Technically Unfeasible Solutions in the Pump Scheduling Problem (2023)

Optimizing pump operation in water networks can effectively reduce the cost of energy. To this end, the literature provides many methodologies, generally based on an optimization problem, that provide the optimal operation of the pumps. However, a persistent shortcoming in the literature is the lack of further analysis to assess if the obtained solutions are feasible from the technical point of view. This paper first showed that some of these available methodologies identify solutions that are technically unfeasible because they induce tank overflow or continuous pump switching, and consequently, proposed a novel approach to avoiding such unfeasible solutions. This consisted in comparing the number of time-steps performed by the hydraulic simulator with the predicted value, calculated as the ratio between the simulation duration and the hydraulic time-step. Finally, we developed a new model which couples Epanet 2.0 with Pikaia Genetic Algorithm using the energy cost as an objective function. The proposed method, being easily exportable into existing methodologies to overcome the limitations thereof, thus represents a substantial contribution to the field of pump scheduling for optimal operation of water distribution networks. The new method, tested on two case studies in the literature, proved its reliability in both cases, returning technically feasible solutions.
How best to add value through continuous professional development: being lectured at by experts or the DIY approach? (2000)

In the first of a new series entitled ‘Provocations’, Dr Eric Watts of Basildon Hospital expresses his anger and concern over time he feels was wasted at a recent conference. He examines traditional educational methods, and suggests that the lecture format widely used in many forms of CPD should no longer automatically be considered first choice.
Nice Knot New Applications in Wrist Arthroscopy (2019)

The use of cerclage alone or as a supplement to other forms of internal fixation is common in orthopedic practice. The Nice knot is a doubled stranded knot described by Boileau and colleagues. Its original application was proposed for tuberosity osteosynthesis in proximal humerus fractures. The Nice knot has been used vastly in shoulder surgery and is now widely use in others surgeries. This article aims to describe the utilization of the Nice knot in wrist arthroscopy to repair the triangular fibrocartilage complex or the scapholunate ligament. We modified the techniques described by Mathoulin for these repairs. The Nice knot is a simple knot, easy to use under arthroscopy to repare the scapholunate ligament and the triangular fibrocartilage complex tears.
FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. II. Structure determination. (1994)

The structure of FR901228 (C24H36N4O6S2), including stereochemical details, was determined by a combination of spectroscopic, chemical evidence and single-crystal X-ray crystallographic analysis using anomalous dispersion from the S atoms.
Solid-state H2 and C2H2 fault-gas microsensors. (2007)

Abstract not provided.
Run-time monitoring and on-line testing of middleware based communication services (2000)

With the present day's exponential growth of the (tele-)communications market, the explosion of the number of mobile communication customers, and the tremendous growth of the number of IP hosts, ensuring the reliability of communication services is one of the most challenging tasks in today's software engineering. This Thesis addresses this problem by providing a new method for increasing confidence in the implementation of communication services. We developed an approach for monitoring and testing communications services that are built on top of a middleware. Specifically, we show how to monitor a communication service and how to use the monitored information to test at runtime whether the behavior of the service conforms to constraints. The constraints are extracted from the requirements, expressed using a formal method. The approach advocated in this Thesis consists in combining the power of formal methods, which have reached a high degree of maturity in the academic domain, with a testing methodology, that fit the industrial needs, in order to test the implementation of a communication service. The developer can thus focus on the testing rather then on how the testing is performed. To solve this problem (1) we designed a monitoring mechanism that is able to observe at run-time, the events occuring in the system under scrutiny, (2) designed a testing mechanism that checks at runtime if properties expressed using Temporal Logic, are violated by the execution of the application, (3) implemented a prototype tool, MOTEL (MOnitoring and TEsting tooL). With our approach the tester need only to specify the properties. The other steps involved in the testing processes are performed automatically. According to the content of the properties the instrumentation is added in the system to be tested. This instrumentation reports a consistent order of the events occurring to a central Observer. Within this Observer, the properties, which are independent of the implementation language, are translated into deterministic automata. At run-time these automata are used, according to the events reported by the instrumentation to the Observer, to check if the properties are violated. Thus, our monitoring and testing mechanism fits well in the development process because it does not add noticeable new steps for the developer. In this thesis we put together many concepts and solutions from various domains (distributed systems, middleware, object-oriented development, CORBA, communication services, formal method, Temporal Logic, automata theory, monitoring, testing). By enhancing, developing and combining, and integrating them together, we reached a high level of integration that provides a new, powerful and useful functionality to test the implementation of communication services. We believe that there is not a more valuable argument for the application and practical relevance of our approach in the industry, than the introduction and use of our method and tool in and by the industry. Our partner, Alcatel, is currently integrating MOTEL in the distributed platform PERCO.
Nonparametric Recognition of Nonrigid Motion (1995)

The recognition of nonrigid motion, particularly that arising from human movement (and by extension from the locomotory activity of animals) has typically made use of high-level parametric models representing the various body parts (legs, arms, trunk, head etc.) and their connections to each other. Such model-based recognition has been successful in some cases; however, the methods are often difficult to apply to real-world scenes, and are severely limited in their generalizability. The first problem arises from the difficulty of acquiring and tracking the requisite model parts, usually specific joints such as knees, elbows or ankles. This generally requires some prior high-level understanding and segmentation of the scene, or initialization by a human operator. The second problem, with generalization, is due to the fact that the human model is not much good for dogs or birds, and for each new type of motion, a new model must be hand-crafted. In this paper, we show that the recognition...
Chiral nanoribbons based on doubly-linked oligo-perylene bisimides (2010)

A facile strategy towards conformationally stable chiral ladder-type oligo-perylene bisimides is established via copper-mediated Ullmann coupling. Absolute configurations are determined with the help of quantum-chemical calculations.
Inhibition of experimental neointimal hyperplasia and thrombosis depends on the type of vascular injury and the site of drug administration. (1993)

The antiproliferative and antithrombotic effects of heparin differ markedly, depending on the type of arterial injury and the mode of drug administration. Different forms of injury may require different therapies, and complications of arterial intervention such as excessive neointimal hyperplasia and thrombosis may demand alternate therapeutic regimens. Duration, dose, and site of delivery rather than frank resistance to therapy may explain why experimentally effective antiproliferative and antithrombotic agents fail clinically.
An IEEE 802.16 WiMAX module for the NS-3 simulator (2009)

ns-3 is a recently released next generation simulator intended as a replacement of the popular ns-2. It enables a highly rich set of features and is expected to become the first choice of the scientific community soon. ns-3 is in its evolution phase and work at different fronts is still ongoing. Wit
Lipopolysaccharides trigger synthesis of the allelochemical sorgoleone in cell cultures of Sorghum bicolor (2020)

The use of plant cell suspension culture systems has demonstrated to be highly suitable for metabolomics investigations of inducible defense responses. Here we report on sorghum cell suspension cultures that were elicited with purified lipopolysaccharides from the sorghum pathogen <i>Burkholderia andropogonis</i>, to activate metabolic pathways involved in the chemical defenses of the plant. Metabolomic analysis using liquid chromatography coupled to mass spectrometry identified a resorcinol phenolic lipid, annotated as sorgoleone, as one of the biomarkers associated with the LPS-induced response. Sorgoleone is a semiochemical and an allelochemical, synthesized by specialized root hair cells and the major component of the hydrophobic root exudate of sorghum. Its detection in undifferentiated cells might indicate a previously undescribed role for this phytochemical in plant defense responses.
FIELD TESTS OF THE LASER INTERROGATION OF SURFACE AGENTS (LISA) SYSTEM FOR ON-THE-MOVE STANDOFF SENSING OF CHEMICAL AGENTS (2003)

Laser Interrogation of Surface Agents (LISA) is a new technique based on short-range Raman sensing that provides standoff detection and identification of surface-deposited chemical agents. ITT Industries, Advanced Engineering and Sciences Division is currently developing the LISA technology under a cost-sharing arrangement with the U.S. Army Soldier and Biological Chemical Command (SBCCOM) for incorporation on the Army’s future reconnaissance vehicles. We will discuss the field-engineered prototype LISA-Recon system, designed to demonstrate single-shot on-the-move measurements of chemical contaminants at concentration levels below the Army’s requirements. Results from laboratory and field tests will be presented. Proper identification of chemical contamination requires an on-board library of high-resolution UV Raman signatures. Laboratory measurements of these Raman spectra are presented in a companion paper.
Coordination de phosphines fonctionnelles et des anions enolates correspondants : application catalytique des complexes du palladium en copolymerisation ethylene/co (1995)

Ce travail de these est base sur la synthese et la coordination de phosphines fonctionnelles du type ph#2pch#2c(o)r avec r = ph (l#1) ou nph#2 (l#2), ainsi que sur la reactivite des anions enolates correspondants. Lorsque ces enolates sont coordines au lithium alors la nature du groupement r pilote son caractere c- et/ou o-nucleophile vis a vis des liaisons p-cl dans les chlorophosphines. Ces reactions chimioselectives conduisent ainsi a une nouvelle diphosphine fonctionnelle (ph#2p)#2chc(o)nph#2 qui associe les proprietes coordinantes d'une dppm (dppm = ph#2pch#2pph#2) a une phosphine fonctionnelle hemilabile. La nature de ces ligands neutres ou anioniques jouant un role crucial dans le procede shop au nickel, differentes syntheses sont presentees permettant d'obtenir les premiers complexes analogues aryles ou alkyles de palladium. Contrairement au nickel, ces complexes sont inactifs en oligomerisation de l'ethylene. Cependant ils sont rendus actifs, par protonation du chelate phosphinoenolate, et catalysent selectivement la dimerisation de l'ethylene ou la copolymerisation ethylene/co. De plus, la nature de ces phosphines fonctionnelles module la stabilite et/ou la reactivite de la liaison palladium-methyle dans ces complexes neutres ou cationiques. Reciproquement, la nature du metal joue un role important sur la reactivite de ces anions phosphinoenolates vis a vis d'un second complexe metalle. Le controle de ces reactions permet d'acceder, par des methodologies de synthese tres differentes, aux bimetalliques paramagnetiques nickel(ii)-cobalt(ii) ou aux complexes binucleaires du palladium(ii). Le coordinat phosphinoenolate dans ces complexes montre qu'il peut se comporter comme un ligand formellement mono ou dianionique, assembleur par l'atome d'oxygene seulement ou avec l'atome de carbone, donneur de 5 ou 4 electrons
Design and Analysis of a Wideband Gilbert Cell VGA in 0.25- $\mu {\rm m}$ InP DHBT Technology With DC-40-GHz Frequency Response (2017)

A differential variable gain amplifier (VGA) for wideband baseband signals has been designed, analyzed, and implemented in a 0.25-μm InP double heterojunction bipolar transistor technology with f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> /f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">max</sub> of 370/650 GHz. The 3-dB frequency bandwidth is measured to be 40 GHz with a maximum gain of 31 dB, resulting in a gain bandwidth product (GBP) of 1.4 THz, four times higher than previously reported GBP from a Gilbert cell-based VGAs. Furthermore, it measures a gain control range of 44 dB, a noise figure of 6.2 dB, an output third-order intercept point of 17 dBm, and a total power consumption of 350 mW from a single -7-V supply. With pseudorandom binary sequence test pattern signals, a clear open eye at 44 Gb/s was observed. The complete circuit, including on-chip integrated bias network and pads, measures 0.77 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . We analyze the VGA for the 3-dB bandwidth and GBP by the use of zero-value time constants method to analytically identify the maximum GBP with respect to the design parameters and current bias.
Forensic handwritten document management system (2008)

Forensic handwriting analysis is an important task in crime investigation. Writers of documents are sometimes unknown or disputed so it is difficult for the forensic detectives to identity of those writers. Currently, forensic professionals perform the analysis of these documents manually. Document management system for forensic document identification, verification and analysis are described. The system is designed to assist forensic document examiner with identifying and comparing Arabic handwriting and its characteristics with a graphical user interface. The same system also provides the examiner with functionalities for retrieving information about documents, region of interest, words, and writers. The system has been implemented using Oracle Database 6i. Our forensic document management system (FDMS) prompts its users with a graphical user interface (GUI) for forensic handwritten document database exploration and management.
Functions and Dysfunctions of Adult Hippocampal Neurogenesis (2014)

Adult neurogenesis, a developmental process of generating functionally integrated neurons, occurs throughout life in the hippocampus of the mammalian brain and showcases the highly plastic nature of the mature central nervous system. Significant progress has been made in recent years to decipher how adult neurogenesis contributes to brain functions. Here we review recent findings that inform our understanding of adult hippocampal neurogenesis processes and special properties of adult-born neurons. We further discuss potential roles of adult-born neurons at the circuitry and behavioral levels in cognitive and affective functions and how their dysfunction may contribute to various brain disorders. We end by considering a general model proposing that adult neurogenesis is not a cell-replacement mechanism, but instead maintains a plastic hippocampal neuronal circuit via the continuous addition of immature, new neurons with unique properties and structural plasticity of mature neurons induced by new-neuron integration.
The confinement tensor model improves characterization of diffusion-weighted magnetic resonance data with varied timing parameters (2016)

Diffusion imaging with confinement tensor (DICT) is a new model that employs a tensorial representation of the geometry confining the movements of water molecules. The model differs substantially from the commonly employed diffusion tensor imaging (DTI) technique even at small diffusion weightings when the dependence of the signal on the timing parameters of the pulse sequence is concerned. In this work, we assess the accuracy of the two models on a data set acquired from an excised monkey brain. The publicly available data set features differing values for diffusion pulse duration and separation. Our results indicate that the normalized mean squared error is reduced in an overwhelming portion of the voxels when the DICT model is employed, suggesting the superiority of DICT in characterizing the temporal dependence of the diffusion process in nervous tissue.