gebhart/patrepeval huggingface dataset:
Observation of elliptic incoherent spatial solitons (2004)

We present the first experimental observation of spatially-incoherent elliptic solitons. We use partially-spatially-incoherent light with anisotropic correlation statistics, and observe elliptic solitons supported by the photorefractive screening nonlinearity.
Coordinate Transcription and Physical Linkage of Domains in Surfactin Synthetase Are Not Essential for Proper Assembly and Activity of the Multienzyme Complex (1998)

Bacterial peptide synthetases have two common features that appear to be strictly conserved. 1) The enzyme subunits are co-regulated at both transcriptional and translational level. 2) The organization of the different enzymatic domains constituting the enzyme fulfills the "colinearity rule" according to which the order of the domains along the chromosome parallels their functional hierarchy. Considering the high degree of conservation of these features, one would expect that mutations such as transcription uncoupling and domain dissociations, deletions, duplications, and reshuffling would result in profound effects on the quality and quantity of synthesized peptides. To start testing this hypothesis, we designed two mutants. In one mutant, the operon structure of surfactin synthetase was destroyed, thus altering the concerted expression of the enzyme subunits. In the other mutant, the thioesterase domain naturally fused to the last amino acid binding domain of surfactin was physically dissociated and independently expressed. When the lipopeptides secreted by the mutant Bacillus subtilis strains were purified and characterized, they appeared to be expressed approximately at the same level of the wild type surfactin and to be identical to it, indicating that specific domain-domain interactions rather than coordinated transcription and translation play the major role in determining the correct assembly and activity of peptide synthetases.
Recognition of Multi-Object Events Using Attribute Grammars (2006)

We present a method for representing and recognizing visual events using attribute grammars. In contrast to conventional grammars, attribute grammars are capable of describing features that are not easily represented by finite symbols. Our approach handles multiple concurrent events involving multiple entities by associating unique object identification labels with multiple event threads. Probabilistic parsing and probabilistic conditions on the attributes are used to achieve a robust recognition system. We demonstrate the effectiveness of our method for the task of recognizing vehicle casing in parking lots and events occurring in an airport tarmac.
New Cardioprotective Agent K201 Is Natriuretic and Glomerular Filtration Rate Enhancing (2006)

We report for the first time that the newly developed cardioprotective drug K201 possesses natriuretic, diuretic, glomerular filtration rate-enhancing, and vasodilating properties that go beyond myocardial actions and may support its therapeutic role in treatment of heart failure.
Design and Performance Evaluation of MORA: a Movement-Based Routing Algorithm for Ad Hoc Networks (2005)

In an ad hoc environment with no wired communication infrastructure, mobile hosts necessarily operate as routers, in order to provide network connectivity. Since mobile ad hoc networks change their topology frequently and without prior notice, routing in such networks becomes a challenging task. To explicitly consider node movements, we present MORA, a movement-based routing algorithm for mobile ad hoc networks. The algorithm is completely distributed, since nodes need to communicate only with direct neighbors within their transmission range, and utilizes a specific metric, which exploits not only the position, but also the direction of movement of mobile hosts. Extensive simulations evaluating the proposed protocol and results of comparison with existing methods demonstrate that MORA can provide an efficient and robust routing strategy.
DIGICOP: A Copyright protection algorithm for Digital Images (2009)

In this Paper, we present a new imperceptible digital watermarking system for images. This system is used for copyright protection, and is compared with base watermarking method (BWM) proposed by Koch et. al. The developed system is called ¿Digital Image Copyright Protector¿ (DIGICOP). It automatically generates the content owner's unique Identification Mark from a supplied text string and a secret key. DCT is used as the embedding domain to achieve high resilience against image processing attacks, such as compression using JPEG, Gaussian Noise, Blurring, Color Inversion, Scaling and Cropping.
COVID-19 and the Heart (2020)

Infection with the severe acute respiratory syndrome novel coronavirus produces a clinical syndrome known as 2019 novel coronavirus disease (COVID-19). When severe, COVID-19 is a systemic illness characterized by hyperinflammation, cytokine storm, and elevations of cardiac injury biomarkers. Here, we review what is known about the pathophysiology of COVID-19, its cardiovascular manifestations, and emerging therapeutic prospects. In this rapidly moving field, this review was comprehensive as of April 3, 2020.
Fixed denial system for access control of nuclear weapons (1981)

The Fixed Denial System (FDS) is a simple, low cost, vertical, underground silo used to store individual nuclear weapons within secured areas of present storage sites. The normal storage position of each weapon is at or near the top of the shaft, allowing rapid operational weapon access and removal. In response to a threat, the weapon within a storage canister can be dropped to the bottom of the shaft where it is automatically locked in place. Once the alert condition is resolved and control of the site reestablished, the weapon canister is unlocked with a coded signal and retrieved. This system offers a high degree of hardening and access denial that is characteristic of Vertical Underground Storage (VUGS) systems. An aboveground test apparatus was constructed to demonstrate the feasibility of using a pneumatic air cushion, which is generated by the free-fall of the weapon container, to control impact velocity and descent time. Stockpile weapons that might be stored in the FDS include the W33, W48, W79, and the W54 ADM.
Inhibitors of Acyl-CoA:Cholesterol O-Acyl Transferase (ACAT) as Hypocholesterolemic Agents. CI-1011:  An Acyl Sulfamate with Unique Cholesterol-Lowering Activity in Animals Fed Noncholesterol-Supplemented Diets (1996)

ADVERTISEMENT RETURN TO ISSUEPREVLetterNEXTInhibitors of Acyl-CoA:Cholesterol O-Acyl Transferase (ACAT) as Hypocholesterolemic Agents. CI-1011: An Acyl Sulfamate with Unique Cholesterol-Lowering Activity in Animals Fed Noncholesterol-Supplemented DietsHelen T. Lee, Drago R. Sliskovic, Joseph A. Picard, Bruce D. Roth, Wendell Wierenga, James L. Hicks, Richard F. Bousley, Katherine L. Hamelehle, Reynold Homan, Cecilia Speyer, Richard L. Stanfield, and Brian R. KrauseView Author Information Departments of Medicinal Chemistry, Radiochemistry, and Vascular and Cardiac Diseases, Parke-Davis Pharmaceutical Research, Division of Warner-Lambert Company, 2800 Plymouth Road, Ann Arbor, Michigan 48105 Cite this: J. Med. Chem. 1996, 39, 26, 5031–5034Publication Date (Web):December 20, 1996Publication History Received26 September 1996Published online20 December 1996Published inissue 1 January 1996https://pubs.acs.org/doi/10.1021/jm960674dhttps://doi.org/10.1021/jm960674drapid-communicationACS PublicationsCopyright © 1996 American Chemical SocietyRequest reuse permissionsArticle Views886Altmetric-Citations81LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Cholesterol,Inhibitors,Peptides and proteins,Plasma,Rodent models Get e-Alerts
Free Volume and Finite-Size Effects in a Polymer Glass under Stress (2007)

Molecular dynamics simulations of the nonlinear creep response of a polymer glass under tension and compression have been performed at the glass transition temperature. The dynamics were measured as the deformation proceeds using the bond autocorrelation function, and the relaxation times measured as the system is compressed or elongated exhibit a universal response. In tension, the volume increases with strain rate and the relaxation times decrease. In compression, however, the volume decreases by approximately the same amount for all of the applied stresses. Thus, decreases in free volume take place alongside a decrease of the relaxation times by over a factor of 100. We find direct evidence that a characteristic length scale exists below which the deformation of the system exhibits distinct anomalies.
The study of magnetic polarity detection method for permanent magnet reluctance motor (2015)

This paper studies a magnetic polarity detection method for permanent magnet reluctance motor (PRM). Inductance characteristic of PRM is different from that of common interior permanent magnet synchronous motor. The inductance characteristic of PRM is verified by electromagnetic field analysis. Moreover, this paper proposes novel magnetic polarity detection method using the inductance characteristic of PRM. The proposed method is verified by experiments using a 90-kW PRM.
Cover Picture: Hydroformylation in the Realm of Scents (ChemCatChem 2/2014) (2014)

A scented trail The cover picture shows two people who have never met in real life: Otto Roelen (1897–1993), the discoverer of the hydroformylation reaction, and Gabrielle Bonheur “Coco” Chanel (1883–1971). Both had completely different lives. He was a cautious scientist who went largely unnoticed, even amongst the community of chemists during his active career. She was the exciting “Grande Dame” of fashion, with the attitude of a liberated and assertive woman. Their paths crossed when Coco, out of several samples developed by her perfumer, opted for sample number 5 (“Chanel No 5”), the sample that happened to contain the highest proportion of linear aldehydes. At this time, in 1922, these aldehydes were extracted from valuable plants. Years later, aldehydes used for this and other famous perfumes can be prepared more easily by hydroformylation with homogeneous catalysts and syngas, as E. V. Gusevskaya, J. Jiménez-Pinto, and A. Börner describe in their Review on p. 382 ff.
Evaluation of polyurethane dressing with ibuprofen in the management of split-thickness skin graft donor sites. (2010)

This study demonstrates that the Biatain-Ibu dressing is a useful tool in the management of STSG donor sites by providing an optimal environment for wound healing due to its bio-occlusive properties and by minimizing pain and discomfort.
Extreme electron polaron spatial delocalization in π-conjugated materials (2015)

The electron polaron, a spin-1/2 excitation, is the fundamental negative charge carrier in π-conjugated organic materials. Large polaron spatial dimensions result from weak electron-lattice coupling and thus identify materials with unusually low barriers for the charge transfer reactions that are central to electronic device applications. Here we demonstrate electron polarons in π-conjugated multiporphyrin arrays that feature vast areal delocalization. This finding is evidenced by concurrent optical and electron spin resonance measurements, coupled with electronic structure calculations that suggest atypically small reorganization energies for one-electron reduction of these materials. Because the electron polaron dimension can be linked to key performance metrics in organic photovoltaics, light-emitting diodes, and a host of other devices, these findings identify conjugated materials with exceptional optical, electronic, and spintronic properties.
Passive mitigation strategies for mode instabilities in high-power fiber laser systems (2013)

Mode instabilities have quickly become the most limiting effect when it comes to scaling the output average power of fiber laser systems. In consequence, there is an urgent need for effective strategies to mitigate it and, thus, to increase the power threshold at which it appears. Passive mitigation strategies can be classified into intrinsic, which are related to the fiber design, and extrinsic, which require a modification of the setup. In order to evaluate the impact of mitigation strategies, a means to calculate its power threshold and predict its behavior is required. In this paper we present a simple semi-analytic formula that is able to predict the changes of the mode instability threshold by analyzing the strength of the thermally-induced waveguide perturbations. Furthermore, we propose two passive mitigation strategies, one intrinsic and one extrinsic, that should lead to a significant increase of the power threshold of mode instabilities.
β‐Ag3RuO4, a Ruthenate(V) Featuring Spin Tetramers on a Two‐Dimensional Trigonal Lattice (2016)

Abstract Open‐shell solids exhibit a plethora of intriguing physical phenomena that arise from a complex interplay of charge, spin, orbital, and spin‐state degrees of freedom. Comprehending these phenomena is an indispensable prerequisite for developing improved functional materials. This type of understanding can be achieved, on the one hand, by experimental and theoretical investigations into known systems, or by synthesizing new solids displaying unprecedented structural and/or electronic features. β‐Ag 3 RuO 4 may serve as such a model system because it possesses a remarkable anionic structure, consisting of tetrameric polyoxoanions (Ru 4 O 16 ) 12− , and is an embedded fragment of a 2D trigonal MO 2 lattice. The notorious frustration of antiferromagnetic (AF) exchange couplings on such lattices is thus lifted, and instead strong AF occurs within the oligomeric anion, where only one exchange path remains frustrated among the relevant six. The strong magnetic anisotropy of the [Ru 4 O 16 ] 12− ion, and the effectively orbital nature of its net magnetic moment, implies that this anion may reveal the properties of a single‐molecule magnet if well‐diluted in a diamagnetic matrix.
You solve, I learn: A novel approach to e-learning in collaborative crowdsourcing (2012)

In collaborative crowdsourcing, the problem of maintaining solvers' motivation and participation plays a crucial role. It has been noticed that one of the major issues is related to the scarce capacity of novices to face expert users in finding good solutions, which leads to an high rate of community abandonment. In order to overcome such a problem the best solvers should be asked to illustrate the rationale of their solutions and to share the adopted heuristics before receiving the award. This procedure allows the less expert to learn by doing and see how best solvers innovate products. The paper presents the “You solve, I learn” approach and how it has been implemented in an original platform able to promote innovation, creativity and effective knowledge sharing. The software use and achieved results are demonstrated through a case study.
A Computer-Based Methodology for the Form Synthesis and Optimal Design of Robot Manipulators (1990)

The study reported in this paper deals with the development of a generalized computer-based methodology for the form synthesis and optimal design of robot manipulators. The developed computer program to implement the methodology operates in two separate modes. The first deals with the synthesis of user defined topologies and in the second mode, the designer provides only the required task, then the program will generate optimum manipulator configuration by systematic evaluation and ranking of plausible alternatives. The methodology simultaneously incorporates kinematic and dynamic synthesis as well as optimal actuation and stress analysis in an integrated design process. The procedure relies on the systematic composition of manipulator configurations from tabulated basic elements. The optimization strategy for synthesis and control utilizes a dynamic programming approach which makes it possible to select the optimum parameters in a stage-wise manner without sacrificing the interactions inherent in such highly coupled nonlinear systems.
Polymere mit dem Zentralatom eines Makrocyclus in der Hauptkette. 4. Kovalenter Einbau von Aluminium‐, Silicium‐ und Germaniumkomplexen des Phthalocyanins in Polyester (1978)

Abstract Phthalocyaninkomplexe des Aluminiums (1) und des Siliciums bzw. Germaniums (2) können über Reaktionen am zentralen Metallion kovalent in Polyester eingebaut werden. Untersuchungen bei der Polykondensation und an fertigen Polyestern aus Adipinsäure/Ethylenglykol(PEA) bzw. Terephthalsäuredimethylester/Ethylenglykol(PET) ergeben, daß der kovalente Einbau von 1, 2 über die Carboxylgruppen an die Metallionen von 1, 2 erfolgt. Bereits durch 10 −4 molare Mengen an Farbstoff werden die Polyester intensiv eingefärbt. Das thermische Verhalten und die hydrolytische Beständigkeit werden nicht beeinflußt. Auf den kovalenten Einbau bei der Polyreaktion von ε‐Caprolacton und bei Polyadditionen wird hingewiesen.
Live‐cell imaging of phosphatidic acid dynamics in pollen tubes visualized by Spo20p‐derived biosensor (2014)

Although phosphatidic acid (PA) is structurally the simplest membrane phospholipid, it has been implicated in the regulation of many cellular events, including cytoskeletal dynamics, membrane trafficking and stress responses. Plant PA shows rapid turnover but the information about its spatio-temporal distribution in plant cells is missing. Here we demonstrate the use of a lipid biosensor that enables us to monitor PA dynamics in plant cells. The biosensor consists of a PA-binding domain of yeast SNARE Spo20p fused to fluorescent proteins. Live-cell imaging of PA dynamics in transiently transformed tobacco (Nicotiana tabacum) pollen tubes was performed using confocal laser scanning microscopy. In growing pollen tubes, PA shows distinct annulus-like fluorescence pattern in the plasma membrane behind the extreme tip. Coexpression studies with markers for other plasmalemma signaling lipids phosphatidylinositol 4,5-bisphosphate and diacylglycerol revealed limited colocalization at the shoulders of the apex. PA distribution and concentrations show distinct responses to various lipid signaling inhibitors. Fluorescence recovery after photobleaching (FRAP) analysis suggests high PA turnover in the plasma membrane. Our data show that a biosensor based on the Spo20p-PA binding domain is suitable for live-cell imaging of PA also in plant cells. In tobacco pollen tubes, distinct subapical PA maximum corroborates its involvement in the regulation of endocytosis and actin dynamics.
Extraction of lipase from Burkholderia cepacia by PEG/Phosphate ATPS and its biochemical characterization (2012)

This work aimed to study the partitioning of a lipase produced by Burkholderia cepacia in PEG/Phosphate aqueous two phase system (ATPS) and its characterization. Lipase was produced by B. cepacia strains in a fermenter. Enzyme partitioning occurred at pH 6.0 and 8.0, using PEG 1500 and 6000 on two tie lines. Metal ions, pH and temperature effects on enzyme activity were evaluated. Five milliliter of 7.5% olive oil emulsion with 2.5% gumarabic in 0.1M sodium phosphate buffer at pH 8.0 and 37ºC were used for the activity determinations. Results showed that crude stratum from B. cepacia was partitioned by PEG1500/phosphate ATPS at pH 6.0 or 8.0 for, which the partitioning coefficients were 108-and 209-folds. Lipase presented optimal activity conditions at 37ºC and pH 8.0; it showed pH-stability for 4 h of incubation at different pH values at 37ºC. Metal ions such as Mn2+ , Co2+, I-and Ca2+ sustained enzymatic activities; however, it was inhibited by the presence of Fe2+, Hg2+ and Al3+ . Km and Vmax values were 0.258 U/mg and 43.90 g/L, respectively. A molecular weight of 33 kDa and an isoelectric point at pH 5.0 were determined by SDS-PAGE and IFS electrophoresis, respectively.
MicroRNA 150-5p Improves Risk Classification for Mortality within 90 Days after Acute Ischemic Stroke (2017)

In patients with ischemic stroke, log-miR-150-5p is a novel prognostic biomarker, highly associated with mortality within 90 days, improving risk classification beyond traditional risk factors.
Stretchable Electronics: Ag Nanowire Reinforced Highly Stretchable Conductive Fibers for Wearable Electronics (Adv. Funct. Mater. 21/2015) (2015)

Stretchable conductive fiber is spotlighted by T. Lee on page 3114 because of the possibility of being utilized in wearable and foldable electronics. Highly stretchable conductive fiber composed of silver nanowires and nanoparticles in a stretchable polymer can be fabricated by using a simple wet spinning method and the use of silver precursor. The composite fiber can be embedded into gloves to perceive human motions.
Basic principles of hybrid excitation PM synchronous generator utilizing harmonic for excitation (2010)

A novel method, which utilizes harmonic for excitation, is presented to adjust the air-gap magnetic field for permanent magnet synchronous machine. The structure and basic principles of the hybrid excitation PM synchronous generator(HEPMSG) are introduced. The no-load and on-load electromagnetic field are calculated based on finite element method, and the waveform and effective value of the winding voltage and characteristics of the machine are gained for different loads. Calculation results demonstrate the new hybrid excitation scheme is feasible. This new method combines the advantages of PM machines and electrical excitation machines. The machine removes the brushes and slip rings, which makes permanent magnet machine keep simple and highly reliable.
Using Conversation Topics for Predicting Therapy Outcomes in Schizophrenia (2013)

Previous research shows that aspects of doctor-patient communication in therapy can predict patient symptoms, satisfaction and future adherence to treatment (a significant problem with conditions such as schizophrenia). However, automatic prediction has so far shown success only when based on low-level lexical features, and it is unclear how well these can generalize to new data, or whether their effectiveness is due to their capturing aspects of style, structure or content. Here, we examine the use of topic as a higher-level measure of content, more likely to generalize and to have more explanatory power. Investigations show that while topics predict some important factors such as patient satisfaction and ratings of therapy quality, they lack the full predictive power of lower-level features. For some factors, unsupervised methods produce models comparable to manual annotation.
ChemInform Abstract: Selenophene Electronics (2014)

Abstract Review: recent syntheses, structure determination, and electronic device properties of π‐conjugated selenophene‐based materials; 88 refs.