gebhart/patrepeval huggingface dataset:
Nanostructured Molybdenum Carbide:  Sonochemical Synthesis and Catalytic Properties (1996)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTNanostructured Molybdenum Carbide: Sonochemical Synthesis and Catalytic PropertiesTaeghwan Hyeon, Mingming Fang, and Kenneth S. SuslickView Author Information School of Chemical Sciences University of Illinois at Urbana−Champaign 505 S. Mathews Avenue, Urbana, Illinois 61801 Cite this: J. Am. Chem. Soc. 1996, 118, 23, 5492–5493Publication Date (Web):June 12, 1996Publication History Received13 November 1995Revised12 April 1996Published online12 June 1996Published inissue 1 January 1996https://doi.org/10.1021/ja9538187Copyright © 1996 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views2752Altmetric-Citations233LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (90 KB) Get e-AlertscloseSUBJECTS:Granular materials,Inorganic carbon compounds,Materials,Molybdenum,Organic reactions Get e-Alerts
Simulation of Temperature Field on Massive Concrete (2011)

Based on the geological conditions of cut and cover tunnel of the South to North Water Transfer Project, lining temperature field for crack control is simulated by finite element software-ANSYS. Through simulation of hydration heat effects, large temperature difference areas can be identified quantitatively, thermal insulation and sprinkler maintenance can be carried on during the initial setting. Cracks can be controlled well by pouring concrete in different section, mixing amount of fly ash and controlling mold temperature reasonable. Thus, model can be optimized continuously, optimal solution will to be established to provide better reference for selecting the temperature control program of massive concrete.
Characterization and FEA Based Optimization of Elastomeric Components for Automotive Applications (2009)

This study aims to show the implementation of an optimization procedure by characterizing the material’s hyperelastic behavior in harsh environments experienced in facility testing and in real world automotive conditions. The procedure consists of conducting material tests under various simulated harsh environments, determining the co-efficients for hyperelastic material modeling and using FEA to predict and correlate the nature of failure observed in facility testing. Two commercially available and commonly employed thermoplastic elastomers (TPE), Santoprene (Ethylene-Propylene-Diene-Monomer rubber and Polypropylene blend) and Desmopan (Thermoplastic Polyurethane), were tested. The harsh environments simulated are fluid immersion tests in automobile grease. Material aging characteristics in controlled thermal conditions were also documented. Compression and tension tests were conducted in order to determine the co-oefficients of the Mooney Rivlin hyperelastic material model. Finite Element Analysis (FEA) simulations were conducted on LS-DYNA software, to determine the quasi-static stress distributions on an overslam bumper part, a typical application of automotive elastomers. Shape and topological variations were investigated in the FEA tests. It was found that certain shape and topological changes to the part result in minimizing the stress concentrations. It is hypothesized that such changes to the rubber component would result in a lower failure rate in facility testing.
Pulse shaping and compression in nonlinear periodic structures with unbalanced Kerr coefficients (2004)

We validate our model with experimental results in a periodic structure consisting of one linear and one resonant nonlinear materials. We show a maximum of 28% pulse compression in both transmitted and reflected pulses.
Wide Nonlinear Chirp Scaling Algorithm for Spaceborne Stripmap Range Sweep SAR Imaging (2017)

The spaceborne stripmap range sweep synthetic aperture radar (SS-RSSAR) is a new concept spaceborne SAR system that images the region of interest (ROI) with ROI-orientated strips, which, unlike the traditional spaceborne SAR, are allowed to be not parallel with the satellite orbit. The SS-RSSAR imaging is a challenging problem because echoes of a wide region have strong spatial varieties, especially in high-squint geometries, and are hard to be focused by a single swath. The traditional imaging algorithms could solve this problem by cost-ineffectively dividing an ROI into many subswaths for separate processing. In this paper, a new wide nonlinear chirp scaling (W-NLCS) algorithm is proposed to efficiently image the SS-RSSAR data in a single swath. Comparing with the traditional nonlinear chirp scaling algorithm, the W-NLCS algorithm is superior in three major aspects: the nonlinear bulk range migration compensation (RMC), the interpolation-based residual RMC, and the modified azimuth frequency perturbation. Specifically, the interpolation for the residual RMC, the most significant step in achieving the wide-swath imaging performance, is made innovatively in the time domain. The derivation of the W-NLCS algorithm, as well as the performance analyses of the W-NLCS algorithm in aspects of the azimuth resolution, accuracy, and complexity, are all provided. The presented approach is evaluated by the point target simulations.
Gap‐43 immunoreactivity and axon regeneration in retinal ganglion cells of the rat (1994)

Retinal ganglion cells (RGCs) in rats were retrogradely labeled with the fluorescent tracer Fluorogold (FG) and subjected to GAP-43 and c-JUN immunocytochemistry to identify those RGCs that are capable of regenerating an axon. After optic nerve section (ONS) and simultaneous application of FG to the nerve stump (group 1 experiments), GAP-43 immunoreactive RGCs (between 2 and 21 days after ONS) always represented a subfraction of both FG-labeled (i.e., surviving) RGCs and RGCs exhibiting c-JUN. GAP-43 immunoreactive RGCs represented 22% of RGCs normally present in rat retinae and 25% of surviving RGCs at 5 days after ONS but were reduced to 2% and 1%, which is 6% and 5% of survivors at 14 and 21 days, respectively. In animals that received a peripheral nerve (PN) graft after ONS (group 2 experiments), RGCs with regenerating axons were identified by FG application to the graft at 14 and 21 days. When examined at 21 and 28 days, all FG-labeled RGCs exhibited GAP-43 immunoreactivity, and FG/GAP-43-labeled RGCs were 3% and 2% of those present in normal rat retinae. In relation to surviving RGCs GAP-43 immunoreactive RGCs represented 10% at both time points. FG-/GAP-43-labeled RGCs also exhibited c-JUN, but c-JUN immunoreactive RGCs were at both time points at least twice as numerous as FG-/GAP-43-labeled RGCs. These data suggest that regenerating axons in PN grafts derive specifically from GAP-43 reexpressing RGCs. Appearance of GAP-43 immunoreactivity may therefore identify those RGCs that are capable of axonal regeneration or sprouting.
Charged-particle-beam-induced processes and their applicability to mask repair for next-generation lithographies (2001)

A comparison of the achievements of charged particle beam induced processes as published is evaluated to judge on the applicability of this technology for Next Generation Lithography mask repair. Methods for repair of defects of different types on different masks are reviewed. This compares the achievements of ion beam technologies as well as of electron beam technologies. With these techniques the properties of the deposited materials for open defect repair can be selected using different precursors, currents, temperatures and voltages for the deposition process. Very high resolution is achievable. For opaque defects the etching and trimming of a surplus of absorber or scattering material with electrons or ions is compared.
Identification, Incidence, and Pathogenicity of Fungal Species Associated with Grapevine Dieback in Texas (2009)

Grapevine cankers and consequent dieback have been commonly observed in Texas vineyards. However, identity of the grapevine canker-causing agents in Texas has not been reported. Between 2007 and 2009, diseased grapevine samples showing perennial cankers from 45 vineyards in Texas were collected and inspected for fungal identification. Eleven fungal species—<i>Lasiodiplodia theobromae</i>, <i>Botryosphaeria dothidea</i>, <i>Neofusicoccum parvum</i>, <i>Diplodia seriata</i>, <i>Diplodia corticola</i>, <i>Phomopsis viticola</i>, <i>Eutypella vitis</i>, <i>Diatrypella</i> sp., <i>Truncatella</i> sp., <i>Pestalotiopsis uvicola</i>, and <i>Pestalotiopsis</i> sp.—were isolated from grapevine cankers and identified based on morphological characteristics and analyses of nucleotide sequences of the internal transcribed spacer region (ITS1-5.8S-ITS2). Botryosphaeriaceae spp. were the most common fungi isolated from grapevine dieback in Texas followed by <i>Pestalotiopsis</i> spp., <i>P. viticola</i>, and Diatrypaceae spp. Pathogenicity of all species was verified by inoculation of excised mature lignified dormant canes of Redglobe and Cabernet Sauvignon grapevines under controlled laboratory conditions. Isolates of <i>L. theobromae</i> and <i>N. parvum</i> were the most virulent based on the length of vascular necrosis in the wood and percentage of fungal re-isolation. <i>Phomopsis viticola</i> isolates followed in virulence to <i>L. theobromae</i> and <i>N. parvum</i> and were shown to be capable of colonizing mature wood and cause vascular necrosis and cankers. The diatrypaceous fungi <i>E. vitis</i> and <i>Diatrypella</i> sp. were the least virulent to grapevines among all fungi tested. All these fungal species represent newly recorded fungal pathogens of grapevines in Texas. Moreover, the association of <i>D. corticola</i> with grapevines is reported.
ON COMPOSITE LIKELIHOODS IN STATISTICAL GENETICS (2011)

Due to the dimension and the dependency structure of genetic data, com- posite likelihood methods have found their natural place in the statistical methodo- logy involving such data. After a brief description of the type of data one encounters in population genetic studies, we introduce the questions of interest concerning the main genetic parameters in population genetics, and present an up-to-date review on how composite likelihoods have been used to estimate these parameters.
Identification and Characterization of a Novel Chemotype MEK Inhibitor Able to Alter the Phosphorylation State of MEK1/2 (2012)

A small molecule compound, JTP-74057/GSK1120212/trametinib, had been discovered as a very potent antiproliferative agent able to induce the accumulation of CDK inhibitor p15INK4b. To conduct its drug development rationally as an anticancer agent, molecular targets of this compound were identified as MEK1/2 using compound-affinity chromatography. It was shown that JTP-74057 directly bound to MEK1 and MEK2 and allosterically inhibited their kinase activities, and that its inhibitory characteristics were similar to those of the known and different chemotype of MEK inhibitors PD0325901 and U0126. It was further shown that JTP-74057 induced rapid and sustained dephosphorylation of phosphorylated MEK in HT-29 colon and other cancer cell lines, while this decrease in phosphorylated MEK was not observed in PD0325901-treated cancer cells. Physicochemical analyses revealed that JTP-74057 preferentially binds to unphosphorylated MEK (u-MEK) in unique characteristics of both high affinity based on extremely low dissociation rates and ability stabilizing u-MEK with high thermal shift, which were markedly different from PD0325901. These findings indicate that JTP-74057 is a novel MEK inhibitor able to sustain MEK to be an unphosphorylated form resulting in pronounced suppression of the downstream signaling pathways involved in cellular proliferation.
Ion Pair Uptake in Ion Gel Devices Based on Organic Mixed Ionic–Electronic Conductors (2021)

Abstract In organic mixed ionic–electronic conductors (OMIECs), it is critical to understand the motion of ions in the electrolyte and OMIEC. Generally, the focus is on the movement of net charge during gating, and the motion of neutral anion–cation pairs is seldom considered. Uptake of mobile ion pairs by the semiconductor before electrochemical gating (passive uptake) can be advantageous as this can improve device speed, and both ions can participate in charge compensation during gating. Here, such passive ion pair uptake in high‐speed solid‐state devices is demonstrated using an ion gel electrolyte. This is compared to a polymerized ionic liquid (PIL) electrolyte to understand how ion pair uptake affects device characteristics. Using X‐ray photoelectron spectroscopy, the passive uptake of ion pairs from the ion gel into the OMIEC is detected, whereas no uptake is observed with a PIL electrolyte. This is corroborated by X‐ray scattering, which reveals morphological changes to the OMIEC from the uptake of ion pairs. With in situ Raman, a reorganization of both anions and cations is then observed during gating. Finally, the speed and retention of OMIEC‐based neuromorphic devices are tuned by controlling the freedom of charge motion in the electrolyte.
Characterizing spin transport: detection of spin accumulation via\n magnetic stray field (2017)

Spin transport in electric conductors is largely determined by two material\nparameters - spin diffusion length and spin Hall angle. In metals, these are\ntypically determined indirectly by probing magnetoresistance in magnet/metal\nheterostructures, assuming knowledge of the interfacial properties. We suggest\nprofiling the charge current induced spin Hall spin accumulation in metals, via\ndetection of the magnetic stray field generated by the associated static\nmagnetization, as a direct means of determining spin transport parameters. We\nevaluate the spatial profile of the stray field as well as the Oersted field\ngenerated by the charge current. We thus demonstrate that such a charge current\ninduced spin accumulation is well within the detection limit of contemporary\ntechnology. Measuring the stray fields may enable direct access to spin-related\nproperties of metals paving the way for a better and consistent understanding\nof spin transport therein.\n
Cooperative Car-Following Control: Distributed Algorithm and Impact on Moving Jam Features (2015)

We design controllers and derive implementable algorithms for autonomous and cooperative car-following control (CFC) systems under a receding horizon control framework. An autonomous CFC system controls vehicle acceleration to optimize its own situation, whereas a cooperative CFC (C-CFC) system coordinates accelerations of cooperative vehicles to optimize the joint situation. To realize simultaneous control of many vehicles in a traffic system, decentralized and distributed algorithms are implemented in a microscopic traffic simulator for CFC and C-CFC controllers, respectively. The impacts of the proposed controllers on dynamic traffic flow features, particularly on formation and propagation of moving jams, are investigated through a simulation on a two-lane freeway with CFC/C-CFC vehicles randomly distributed. The simulation shows that the proposed decentralized CFC and distributed C-CFC algorithms are implementable in microscopic simulations, and the assessment reveals that CFC and C-CFC systems change moving jam characteristics substantially.
A 100dB dynamic range cmos image sensor using a lateral overflow integration capacitor (2005)

The wide DR CMOS image sensor incorporates a lateral overflow capacitor in each pixel to integrate the overflow charges from the photodiode when it saturates. The 7.5/spl times/7.5 /spl mu/m/sup 2/ pixel, 1/3" VGA sensor fabricated in a 0.35 /spl mu/m 3M2P CMOS process achieves a 100 dB dynamic range with no image lag, 0.15 mV/sub rms/ random noise and 0.15 mV fixed pattern noise.
Caractérisation et modélisation probabiliste des milieux hétérogènes (2018)

International audience
Critical evaluation of the use of dogs in biomedical research and testing (2011)

355 Critical Evaluation of the Use of Dogs in Biomedical Research and Testing Joanne Zurlo 1, Kathryn A. Bayne 2, Dorothy Cimino Brown 3, Tanya H. Burkholder 4, Vicki L. Dellarco 5, Amy Ellis 6, Laura Garrett 7, Robert Hubrecht 8, Erik R. Janus 9, Lewis B. Kinter 10, Elizabeth Luddy 11, LaVonne D. Meunier 12, Diana G. Scorpio 13, James A. Serpell 14, and Rory J. Todhunter 15 Center for Alternatives to Animal testing, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; AAAlAC International, Frederick, MD, USA; University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA; Division of Veterinary Resources, Office of the Director, National Institutes of Health, Bethesda, MD, USA; Office of Pesticides, US environmental Protection Agency, Washington, DC, USA; Center for Drug evaluation and Research, US Food and Drug Administration, Silver Spring, MD, USA; University of Illinois, College of Veterinary Medicine, UrbanaChampaign, Il, USA; Universities Federation for Animal Welfare, Wheathampstead, Hertfordshire, UK; Steptoe & Johnson, llP, Washington, DC, USA; AstraZeneca Pharmaceuticals lP, Wilmington, De, USA; Center for Veterinary Medicine, US Food and Drug Administration, Rockville, MD, USA; GlaxoSmithKline, King of Prussia, PA, USA; Department of Molecular and Comparative Pathobiology, Johns Hopkins School of Medicine, Baltimore, MD, USA (current address: California National Primate Research Center, University of California, Davis); University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, USA; Cornell University College of Veterinary Medicine, Ithaca, NY, USA
Bis(maltolato)oxovanadium(IV) is a potent insulin mimic (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBis(maltolato)oxovanadium(IV) is a potent insulin mimicJohn H. McNeill, V. G. Yuen, H. R. Hoveyda, and Chris OrvigCite this: J. Med. Chem. 1992, 35, 8, 1489–1491Publication Date (Print):April 1, 1992Publication History Published online1 May 2002Published inissue 1 April 1992https://pubs.acs.org/doi/10.1021/jm00086a020https://doi.org/10.1021/jm00086a020research-articleACS PublicationsRequest reuse permissionsArticle Views908Altmetric-Citations343LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Exercise cardiac MR assessment of diastolic function (2015)

Values are reported as mean standard deviation (range). There were trends of higher E-and A-velocities and E/A ratios, but the increase in E-velocity was only significant in subjects in whom heart rate increased >20bpm relative to rest.
Defect analysis of degraded InGaP/GaAs HBTs (2005)

The reliability of InGaP/GaAs HBTs has been investigated widely. In order to understand the degradation mechanism, degraded HBTs were analysed in TEM and the diffusion behaviour of elements was investigated with EDXS. Dislocations were observed having their origin in the base emitter junction. Similarities with dislocations in degraded LEDs and LDs were observed. Indium diffusion out of the emitter can be detected, whereas dislocations in the emitter seem to block the out diffusion of indium. No carbon precipitations were found in the base-emitter junction area of the degraded HBTs.
Lipid-Free Structure and Stability of Apolipoprotein A-I:  Probing the Central Region by Mutation (2002)

To probe the structure and stability of the central region of lipid-free apolipoprotein (apo) A-I (residues 123−165), we studied the effects of four mutations made in this region on the conformation, stability, dimyristoylphosphatidylcholine (DMPC) binding kinetics, and size of discoidal reconstituted high-density lipoprotein (rHDL) particles. The apoA-I deletion Δ(144−165) leads to a red shift in the wavelength of maximum fluorescence and a reduction in the α-helical content, the stability, the initial rate of association with DMPC liposomes, and the size of the discoidal particles. The data are consistent with the helical structure of residues 144−165, and the deletion appears to perturb the tertiary organization of the N-terminal half of apoA-I. In contrast, the deletion of the adjacent region, Δ(136−143), leads to stabilization without altering the number of residues in the helical conformation or the initial rate of association with DMPC liposomes. The quadruple substitution E125K/E128K/K133E/E139K leads to ∼17 additional residues in the helical conformation and an increase in the stability, the initial rate of association with DMPC liposomes, and the size of the rHDL particles. The findings are consistent with the disordered structure of the segment of residues 123−142, which becomes helical as a result of the quadruple mutation or upon lipid binding. The naturally occurring mutation L141R (also associated with coronary heart disease) that is located in this segment does not change the protein conformation but leads to a reduced stability and a decreased rate of association with DMPC liposomes that may relate to the observed altered functions of this mutant.
Ab Initio and Nonlocal Density Functional Study of 1,3,5-Trinitro-s-triazine (RDX) Conformers (1997)

Geometry optimizations and normal-mode analyses of three conformers of 1,3,5-trinitro-s-triazine (RDX) are performed using second-order Moller−Plesset (MP2) and nonlocal density functional theory (DFT) methods. The density functional used in this study is B3LYP. The three conformers of RDX are distinguished mainly by the arrangement of the nitro groups relative to the ring atoms of the RDX molecule. NO2 groups arranged in either pseudo-equatorial or axial positions are denoted with (E) or (A), respectively. The AAE conformer has Cs symmetry and is the structure in the room-temperature stable crystal (α-RDX). The AAA and EEE conformers have C3v symmetry, a symmetry consistent with vapor and β-solid infrared spectra. The AAE and AAA conformers are studied at the MP2/6-31G*, B3LYP/6-31G*, and B3LYP/6-311+G** levels, and the EEE conformer is studied using the B3LYP density functional and the 6-31G* and 6-311+G** basis sets. The geometric parameters and infrared spectra of the AAA conformer are in good agreement with experimental gas-phase and β-solid data, supporting the hypotheses derived from experiment that the AAA structure is the most probable conformer in vapor-phase and β-solid RDX. The B3LYP/6-311+G** structures and simulated infrared spectra are in closest overall agreement with experimental data. The MP2/6-31G* structures and spectra are in poorest overall agreement with experiment.