gebhart/patrepeval huggingface dataset:
Spatialized audio rendering for immersive virtual environments (2002)

We present a spatialized audio rendering system for the use in immersive virtual environments. The system is optimized for rendering a sufficient number of dynamically moving sound sources in multi-speaker environments using off-the-shelf audio hardware. Based on simplified physics-based models, we achieve a good trade-off between audio quality, spatial precision, and performance. Convincing acoustic room simulation is accomplished by integrating standard hardware reverberation devices as used in the professional audio and broadcast community. We elaborate on important design principles for audio rendering as well as on practical implementation issues. Moreover, we describe the integration of the audio rendering pipeline into a scene graph-based virtual reality toolkit.
Ritalin: Theory and Patient Management (1991)

PRAC can improve the survival of colorectal cancer patients.
Diffusion filtering of depth maps in stereo video coding (2010)

A method for removing irrelevant information from depth maps in Video plus Depth coding is presented. The depth map is filtered in several iterations using a diffusional approach. In each iteration smoothing is carried out in local sample neighborhoods considering the distortion introduced to a rendered view. Smoothing is only applied when the rendered view is not affected. Therefore irrelevant edges and features in the depth map can be damped while the quality of the rendered view is retained. The processed depth maps can be coded at a reduced rate compared to unaltered data. Coding experiments show gains up to 0.5 dB for the rendered view at the same bit rate.
Systeme de modelisation de l'environnement a base d'objets pour la robotique application a l'interpretation d'images 3d denses (1990)

La comprehension de l'environnement est un des maillons essentiel de la resolution de problemes en robotique autonome. Une reponse possible consiste a mettre en correspondance des informations fournies par un systeme de capteurs avec des modeles. Dans notre systeme, les mises en correspondance sont guidees pour des modeles definis. Les modeles sont definis par des classes au sens des representations objet. L'ensemble des modeles definit une taxinomie. Cette taxinomie permet d'expliciter les proprietes communes a plusieurs modeles. Cette structure est utilisee pour l'identification: les elements sont associes par etape a des modeles de plus en plus precis. L'association d'un element a un modele se fait lorsque cet element ne peut correspondre a un autre type d'objets. Les identifications sont testees sur des images 3d denses. L'analyse d'image comporte 2 phases. Pour la premiere il s'agit d'une segmentation en region plane par une technique de croissance de region. Les contours des regions sont ensuite determines a partir de l'intersection des plans d'une part et par une segmentation polygonale recursive d'autre part. Ces contours et ces plans servent de base pour les identifications
Mathematical programming approaches to machine learning and data mining (1998)

Machine learning problems of supervised classification, unsupervised clustering and parsimonious approximation are formulated as mathematical programs. The feature selection problem arising in the supervised classification task is effectively addressed by calculating a separating plane by minimizing separation error and the number of problem features utilized. The support vector machine approach is formulated using various norms to measure the margin of separation. The clustering problem of assigning m points in n-dimensional real space to k clusters is formulated as minimizing a piecewise-linear concave function over a polyhedral set. This problem is also formulated in a novel fashion by minimizing the sum of squared distances of data points to nearest cluster planes characterizing the k cluster. The problem of obtaining a parsimonious solution to a linear system where the right hand side vector may be corrupted by noise is formulated as minimizing the system residual plus either the number of nonzero elements in the solution vector or the norm of the solution vector. The feature selection problem, the clustering problem and the parsimonious approximation problem can all be stated as the minimization of a concave function over a polyhedral region and are solved by a theoretically justifiable, fast and finite successive linearization algorithm. Numerical tests indicate the utility and efficiency of these formulations on real-world databases. In particular, the feature selection approach via concave minimization computes a separating-plane based classifier that improves upon the generalization ability of a separation plane computed without feature suppression. This approach produces classifiers utilizing fewer original problem features than the support vector machine approaches, with comparable generalization ability. The clustering techniques are showing to be effective and efficient data mining tools in medical survival analysis applications. The parsimonious approximation methods yield improved results in a signal processing application, with high signal to noise ratio, over least squares and a lengthy combinatorial search. These results support the claim that mathematical programming is effective as the basis of data mining tools to extract patterns from a database which contain "knowledge" and thus achieve "knowledge discovery in databases".
Search for an optimal multistage charging pattern for lithium-ion batteries using the Taguchi approach (2009)

Commercial lithium-ion batteries are playing important roles as energy storage solutions for portable devices, automotive electronics and renewable energy systems. In order to maximize the performance of lithium-ion batteries, an advanced charging pattern is required. In this paper, a Taguchi-based algorithm is presented. Orthogonal arrays are implemented to determine the optimal charging pattern for multistage constant current charging method. Experimental results show that the obtained charging pattern is capable of charging the lithium-ion batteries to 75% capacity in 40 minutes. The obtained pattern also provides 60% more cycle life than the conventional constant current-constant voltage method.
Improved pharmacokinetics and tumor localization of immunotoxins constructed with the Mr 30,000 form of ricin A chain. (1991)

The two naturally occurring forms of ricin A chain, Mr 33,000 and Mr 30,000 (RTA33 and RTA30) have been purified, and their chemical compositions, toxicities, and tissue distributions have been determined. As reported previously, the in vitro and in vivo toxicities of RTA30 and RTA33 are similar. However, RTA30, which contains less carbohydrate with a lower mannose content than RTA33, accumulated less in the liver than did RTA33. Monoconjugate immunotoxins (i.e., containing one RTA per monoclonal antibody molecule) were constructed between RTA30 or RTA33 and the antitumor monoclonal antibody 791T/36, which recognizes a Mr 72,000 antigen on osteosarcoma and colon carcinoma cells. The two immunotoxins had similar cytoxicities in vitro but differed substantially in their pharmacokinetics and tissue distributions in vivo in nude mice bearing C170 human colorectal carcinoma xenografts. The immunotoxin derived from RTA30 (IT30) accumulated less in the liver than the immunotoxin derived from RTA33 (IT33) and cleared more slowly from the blood; the alpha and beta half-lives for IT30 and IT33 were 0.50 and 20.5 versus 0.17 and 14.6 h, respectively. As a probable consequence, IT30 accumulated to approximately 3-fold higher levels in the C170 xenografts than IT33. The reduced clearance of IT30 by the reticuloendothelial system thus resulted in prolonged survival in the blood and enhanced tumor localization relative to IT33.
Protein-Based Surfactants: Synthesis: Physicochemical Properties, and Applications (2001)

An overview of the basis, technology, and surface phenomena of protein-based surfactants natural raw materials and enzymatic modification of agricultural by-products for protein-based surfactants protein interaction at interfaces amino acid surfactants - chemistry, synthesis and properties enzyme-catalyzed synthesis of protein-based surfactants - amphoteric surfactants arginine lipopeptide surfactants with antimicrobial activity essentially fluorinated synthetic surfactants based on amino acids or oligopeptides interactions of amino acid-based surfactants with other compounds potential applications of protein-based surfactants current market developments and trends in amino acid- and protein-based surfactants.
Epac1 activation and progenitor-cell homing (2008)

The article by Carmona and colleagues in this issue of Blood demonstrates that activation of Epac1 increases integrin activity and integrin-dependent homing functions of progenitor cells and enhances their in vivo therapeutic potential.
Some Aspects Of The Formation Of Laser Clad Tracks (1986)

Laser surface cladding with argon blown powder<sup>1</sup> is a process whereby a powder stream is blown into a laser-generated melt pool. The mechanisms in this melt pool which determine the opidmum operating conditions for low dilution, zero porosity and a continuous clad track are discussed. A dilution parameter and a porosity parameter are derived and compared to experiment. Some factors affecting their values are identified.
A comparison of phorbol myristate acetate with phytohemgglutinin as a stimulator of in vitro colony growth of peripheral human leucocytes. (1980)

Peripheral blood mononuclear cells from normal individuals were cultured in soft agar (0.3%) with either phytohaemagglutinin (PHA) or the tumor promoter phorbol myristate acetate (PMA). PMA was found to induce colony growth under these conditions as well as that achieved by PHA. The colonies from PHA stimulation were entirely lymphoid but with PMA the type of cell was more varied with some cells that appeared to be of the granulocytic-macrophage line. PMA thus appears to have the ability to promote growth in cells other than lymphocytes in the peripheral blood under these conditions.
On spectrum sharing between communications and air traffic control radar systems (2015)

The feasibility of dynamic spectrum sharing between air traffic control radar and wireless communications systems is investigated via a numerical simulation. The temporal variations of interference power due to periodic rotations of the radar antenna and the interference attenuation resulting from frequency separation can substantially contribute to link loss. Consequently, even in the scenario where cellular devices are located close to the radar, there still will be periods of time when the mutual interference is low enough such that cellular systems can take opportunity to transmit. Numerical results show that in the scenario where spectrum sharing between a single cell and the single rotating radar is considered, although both systems are subject to certain levels of performance degradation due to the impact each has on the other, the design of efficient spectral sharing mechanisms is still possible.
ChemInform Abstract: Arylthiols as Highly Chemoselective and Environmentally Benign Radical Reducing Agents. (2009)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Data from Glutamine Metabolism Mediates Sensitivity to Respiratory Complex II Inhibition in Acute Myeloid Leukemia (2023)

&lt;div&gt;Abstract&lt;p&gt;Acute myeloid leukemia (AML) is a hematologic malignancy metabolically dependent on oxidative phosphorylation and mitochondrial electron transport chain (ETC) activity. AML cells are distinct from their normal hematopoietic counterparts by this metabolic reprogramming, which presents targets for new selective therapies. Here, metabolic changes in AML cells after ETC impairment are investigated. Genetic knockdown of the ETC complex II (CII) chaperone protein SDHAF1 (succinate dehydrogenase assembly factor 1) suppressed CII activity and delayed AML cell growth &lt;i&gt;in vitro&lt;/i&gt; and &lt;i&gt;in vivo&lt;/i&gt;. As a result, a novel small molecule that directly binds to the ubiquinone binding site of CII and inhibits its activity was identified. Pharmacologic inhibition of CII induced selective death of AML cells while sparing normal hematopoietic progenitors. Through stable isotope tracing, results show that genetic or pharmacologic inhibition of CII truncates the tricarboxylic acid cycle (TCA) and leads to anaplerotic glutamine metabolism to reestablish the truncated cycle. The inhibition of CII showed divergent fates, as AML cells lacked the metabolic plasticity to adequately utilize glutamine metabolism, resulting in preferential depletion of key TCA metabolites and death; normal cells were unaffected. These findings provide insight into the metabolic mechanisms that underlie AML's selective inhibition of CII.&lt;/p&gt;Implications:&lt;p&gt;This work highlights the effects of direct CII inhibition in mediating selective AML cell death and provides insights into glutamine anaplerosis as a metabolic adaptation that can be therapeutically targeted.&lt;/p&gt;&lt;/div&gt;
Accelerating search and recognition workloads with SSE 4.2 string and text processing instructions (2011)

Today's information is increasing rapidly, doubling every three years. Consequently, the search and recognition stages in computer applications will consume a growing portion of the total CPU time. The SSE 4.2 instruction set, first implemented in Intel's Core i7, provides string and text processing instructions (STTNI) that utilize SIMD operations for processing character data. Though originally conceived for accelerating string, text, and XML processing, the powerful new capabilities of these instructions are useful outside of these domains, and it is worth revisiting the search and recognition stages of numerous applications to utilize STTNI to improve performance. In this paper, we explored the feasibility and potential benefit of using STTNI to improve the CPU and memory performance of search-and-recognition applications. We optimized four benchmark applications - cache simulation, B+tree search algorithm, template matching, Basic Local Alignment Search Tool (BLAST) - with STTNI, and the new applications outperform their respective original implementations by a factor of 1.4× to 13×.
Analysis of MAC protocols for wireless-ATM networks (2002)

This paper focuses on the analysis of two classes of TDMA-based MAC algorithms for wireless-ATM networks: the urgency-based class, scheduling the bandwidth requests on the basis of their urgency, and the buffer-based class, relying on the estimation of the queue length in the mobile terminals. The main features of the proposed urgency-based algorithms are: contention-based DAMA access, dynamic adaptation of reservation bandwidth, use of piggybacking and control mini-slots to handle real-time VBR traffic, and a scheduling mechanism based on the expiry time of the buffered cells. These aspects contribute to the better performance of urgency-based algorithms in handling heterogeneous traffic when compared to the buffer-based ones.
Selective Single‐Step Separation of a Mixture of Three Metal Ions by a Triphasic Ionic‐Liquid–Water–Ionic‐Liquid Solvent Extraction System (2015)

In a conventional solvent extraction system, metal ions are distributed between two immiscible phases, typically an aqueous and an organic phase. In this paper, the proof-of-principle is given for the distribution of metal ions between three immiscible phases, two ionic liquid phases with an aqueous phase in between them. Three-liquid-phase solvent extraction allows separation of a mixture of three metal ions in a single step, whereas at least two steps are required to separate three metals in the case of two-liquid-phase solvent extraction. In the triphasic system, the lower organic phase is comprised of the ionic liquid betainium- or choline bis(trifluoromethylsulfonyl)imide, whereas the upper organic phase is comprised of the ionic liquid trihexyl(tetradecyl)phosphonium bis(trifluoromethylsulfonyl)imide. The triphasic system was used for the separation of a mixture of tin(II), yttrium(III), and scandium(III) ions.
Topic: Designing the Future Internet (2007)

Dr. Durresi received his B.Eng., M.Eng. and Ph.D. (all summa cum laude) in Electronics and Telecommunications, in 1986, 1991 and 1993, respectively; and a Diploma of Superior Specialization in Telecommunications from La Sapienza University in Rome, Italy and Italian Telecommunications Institute.
Modulation of gamma-aminobutyric acid-mediated inhibitory synaptic currents in dissociated cortical cell cultures. (1986)

Inhibitory gamma-aminobutyric acid-mediated synaptic currents were studied in dissociated primary cultures of neonatal rat cortex with the whole-cell patch-clamp technique. Immunocytochemical staining of the cultures showed the presence of a large number of glutamic acid decarboxylase-containing neurons, and electrical stimulation of randomly selected neurons produced in many cases chloride-mediated and bicuculline-sensitive inhibitory synaptic currents in postsynaptic cells. The amplitude and decay time of the inhibitory synaptic currents were increased by flunitrazepam and decreased by the beta-carboline derivative methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate, two high-affinity ligands for the allosteric regulatory sites of gamma-aminobutyric acid receptors. The imidazobenzodiazepine Ro 15-1788, another high-affinity ligand of the gamma-aminobutyric acid receptor regulatory sites that has negligible intrinsic activity, blocked the action of flunitrazepam and beta-carboline. However, Ro 15-1788 also increased the decay rate of the inhibitory synaptic currents. This might suggest that an endogenous ligand for the benzodiazepine-beta-carboline binding site is operative in gamma-aminobutyric acid-mediated synaptic transmission.
The Impact of Determinism on Learning Atari 2600 Games (2015)

Atari 2600 games are deterministic given a fixed policy leading to a fixed sequence of actions. This article investigates three methods for adding randomness: random initialization, epsilon-greedy action selection, and epislon-repeat action selection. These methods are evaluated by how well they are able to derail a memorizing agent without hurting the performance of a randomized agent. Results indicate that epsilon-repeat action selection best fits the desired criteria and lower values of epsilon than previously used are sufficient to derail the memorizing agent.
A robust close-range photogrammetric target extraction algorithm for size and type variant targets (2016)

The Photo-G program conducted by Naval Air Systems Command at the Atlantic Test Range in Patuxent River, Maryland, uses photogrammetric analysis of large amounts of real-world imagery to characterize the motion of objects in a 3-D scene. Current approaches involve several independent processes including target acquisition, target identification, 2-D tracking of image features, and 3-D kinematic state estimation. Each process has its own inherent complications and corresponding degrees of both human intervention and computational complexity. One approach being explored for automated target acquisition relies on exploiting the pixel intensity distributions of photogrammetric targets, which tend to be patterns with bimodal intensity distributions. The bimodal distribution partitioning algorithm utilizes this distribution to automatically deconstruct a video frame into regions of interest (ROI) that are merged and expanded to target boundaries, from which ROI centroids are extracted to mark target acquisition points. This process has proved to be scale, position and orientation invariant, as well as fairly insensitive to global uniform intensity disparities.
Myrtenal inhibits acetylcholinesterase, a known Alzheimer target (2011)

Our investigations provided evidence for the efficacy of monoterpenes as inhibitors of AChE.
YCoCg-R: A Color Space with RGB Reversibility and Low Dynamic Range (2003)

At the latest JVT meeting we presented the YCoCg color space, including its simple transformation equations relative to RGB and its improved coding gain relative to both RGB and YCbCr. We also discussed the reversibility of RGB to YCoCg conversion process in the case that two additional bits of precision are used for YCoCg relative to the precision used for source RGB data. In this proposal, we additionally present a variation of this color space, which we call YCoCg-R. The YCoCg color space has been applied to JPEG XR image compression and to texture compression through the YCoCg-DXT algorithm.
Features of p53 protein distribution in the corneal epithelium and corneal tear film (2020)

Tumor suppressor protein p53 is the key factor in the regulation of cell proliferation. Its concentration is low in the cytoplasm of most cell types. However, in corneal epithelium cells, abnormally high p53 content is detected. The aim of the present study was to characterize p53 distribution in the corneal epithelium. For this purpose, immunohistochemistry, western blot analysis and electronic microscope examinations were performed. A low level of p53 was identified in the lens, iris and retina; by contrast, a significantly high concentration of this protein was observed in the corneal epithelium. In opposite, MDM2 was identified in the lens, iris and retina while it is completely absent in the corneal epithelium. In addition, we found a significant amount of exosomes and other microvesicles containing p53 in the corneal mucin layer. We thus hypothesize that a significantly high level of p53 was caused by a combination of absents of MDM2 in parallel with p53 microvesicles storage.
Bifidobacterium longumBBMN68-specific modulated dendritic cells alleviate allergic responses to bovineβ-lactoglobulin in mice (2015)

These data confirm that BBMN68 may be a suitable therapeutic approach to the alleviation of food allergies, and BBMN68-specific induction of CD11c+CD103+DCs and semi-mature DCs are associated with this protection.
Factors Controlling Attachment of Bryozoan Larvae: A Comparison of Bacterial Films and Unfilmed Surfaces (1989)

The effects of individual species of marine bacteria on the attachment of larvae of the bryozoan Bugula neritina were examined in the laboratory. Bacteria, grown to mid-exponential phase and allowed to adsorb to polystyrene petri dishes, attached at densities of 106-107 cells cm–2. Bryozoan attachment assays (30 min) were used to compare the effects of adsorbed cells of three species of bacteria with unfilmed surfaces. Larvae permanently attached, at high percentages (65-94%), to unfilmed polystyrene, hydrophobic (i.e., low wettability, low surface energy) control surfaces. This activity agrees with reports in the literature. Films of individual species of bacteria can influence bryozoan attachment. Three separate strains of the bacterial species Deleya marina inhibited attachment, but two other species of marine bacteria did not. Measurements indicated that all five bacteria tested differed in their cell-surface hydrophobicity, but that their films were similar in that they were all highly wettable (i.e., high surface free energy). Our data indicate that factors in addition to substratum surface energy determine attachment of bryozoan larvae especially when bacterial films are present. Bacterial extracellular materials may be involved.