gebhart/patrepeval huggingface dataset:
Indigo Naturalis Oil Extract Drops in the Treatment of Moderate to Severe Nail Psoriasis: A Small Case Series (2011)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Dermatology HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Dermatology journal
Optical Disc System Controller Design Based on a Disturbance Detector (2009)

An Optical disk driver is used in many electronic products besides the computers. In particular, the demands are recently increased as an optical disk player/recorder in the mobile products such as camcorder, portable player or in the home theater appliances, etc. However, the more the mobility is emphasized, the more the optical disk player is exposed to the disturbance inputs. For reducing the possibility of malfunction of the optical disk, we propose a nonlinear controller using the disturbance detecting algorithm based on the Kalman filter. Actual experiments were executed to verify the performance of the proposed method. The proposed method controls the tracking error signal within .
Entanglement between the Future and the Past in the Quantum Vacuum (2011)

We note that massless fields within the future and past light cone may be quantized as independent systems. The vacuum is shown to be a nonseparable state of these systems, exactly mirroring the known entanglement between the spacelike separated Rindler wedges. This leads to a notion of timelike entanglement. We describe an inertial detector which exhibits a thermal response to the vacuum when switched on at t=0, due to this property. The feasibility of detecting this effect is discussed, with natural experimental parameters appearing at the scale of 100 GHz.
Towards rich information landscapes for visualising structured Web spaces (2002)

The Harmony browser for the Hyper-G Web server utilises Hyper-G's rich data model to provide a number of tightly-coupled, two- and three-dimensional visualisation and navigational facilities. In particular the Harmony Information Landscape visualises the hierarchical structure of Hyper-G spaces upon a plane in three-dimensional space. The Harmony Information Landscape has now been extended to display a combined structure and link map by selectively superimposing hyperlink relationships in the vertical dimension above and below the hierarchy map. In addition, documents returned by search queries may be selectively "plotted" in the landscape, indicating their whereabouts in a broader context, and several sets of 3D icons are available for representing the various document types.
A conical panoramic stereo imaging system for 3-D scene reconstruction (2003)

The concept of a "conical panorama" was introduced in an earlier paper, involving the view of an oblique down-look camera rotating about an axis, either directly through or at some distance from the center of projection. This provides the framework 1) to analyze multi-camera realizations developed for various underwater visual tasks, and 2) to develop methods for the computation of visual motion that are more robust relative to processing of images covering a finite field of view. This paper presented a stereo conical imaging system, comprising 12 cameras with relatively large overlap between pairs of neighboring cameras. This panoramic stereovision system is targeted for 3-D visualization and improved scene reconstruction by utilizing correspondences in more than 2 views of the scene at modest distances. The calibration of the system is addressed, and experimental results demonstrate the potential in the use of this system for 3-D mapping.
Nitrogen–Fluorine Dual Doped Porous Carbon Derived from Silk Cotton as Efficient Oxygen Reduction Catalyst for Polymer Electrolyte Fuel Cells (2019)

Porous carbon derived from silk cotton and heteroatom engineering is explored in this study for developing metal-free electrocatalysts for oxygen reduction (ORR). Individual and dual doping of N and F heteroatoms was conducted to regulate defects and the pore geometry to the porous carbon matrix. Microscopic analysis of N–F co-doped cotton carbon (N–F/CTC) undergoes morphological amendments in its textural properties and defects responsible in creating active sites for ORR. N–F/CTC catalyst exhibits excellent ORR catalytic activity and methanol and CO tolerance in the alkaline medium, which makes it a potential metal-free ORR catalyst for the polymer electrolyte membrane fuel cell. N–F/CTC catalyst is subjected to 10 000 repeated potential cycles with no degradation in its activity. XPS analysis of N–F/CTC catalyst revealed the presence of N in the form of pyridinic-N, pyrrolic-N, graphitic-N, active species, and F in the form of C–F ionic and C–F semi-ionic active forms. The maximum C–C bond polarization, charge redistribution, and high spin densities in the carbon matrices are attained by all these active forms present in the catalyst and synergistically enhance the ORR activity.
Nickel-in-Charcoal (Ni/C): An Efficient Heterogeneous Catalyst for the Construction of C-C, C-N, and C-H Bonds (2005)

The preparation and use of nickel-in-charcoal as an environmentally benign and inexpensive alternative to solution-based palladium­-catalyzed cross-couplings are described.
High-Speed-Operation of All-Silicon Lumped-Electrode Modulator Integrated with Passive Equalizer (2020)

Silicon photonics technology is a promising candidate for small form factor transceivers that can be used in data-center applications. This technology has a small footprint, a low fabrication cost, and good temperature immunity. However, its main challenge is due to the high baud rate operation for optical modulators with a low power consumption. This paper investigates an all-Silicon Mach-Zehnder modulator based on the lumped-electrode optical phase shifters. These phase shifters are driven by a complementary metal oxide semiconductor (CMOS) inverter driver to achieve a low power optical transmitter. This architecture improves the power efficiency because an electrical digital-to-analog converter (DAC) and a linear driver are not required. In addition, the current only flows at the time of data transition. For this purpose, we use a PIN-diode phase shifter. These phase shifters have a large capacitance so the driving voltage can be reduced while maintaining an optical phase shift. On the other hand, this study integrates a passive resistance-capacitance (RC) equalizer with a PIN-phase shifter to expand the electro-optic (EO) bandwidth of a modulator. Therefore, the modulation efficiency and the EO bandwidth can be optimized by designing the capacitor of the RC equalizer. This paper reviews the recent progress for the high-speed operation of an all-Si PIN-RC modulator. This study introduces a metal-insulator-metal (MIM) structure for a capacitor with a passive RC equalizer to obtain a wider EO bandwidth. As a result, this investigation achieves an EO bandwidth of 35.7-37 GHz and a 70 Gbaud NRZ operation is confirmed.
INTRACELLULAR SURVIVAL OF STAPHYLOCOCCI (1959)

A tissue culture procedure is described which permits the quantitative evaluation of the intracellular survival of staphylococci within leucocytes. Staphylococcus aureus survived, but did not multiply, within neutrophils and monocytes of normal rabbits. The same was true of normal human blood leucocytes. Staphylococcus albus on the other hand was destroyed by these cells under the same conditions. Rat monocytes destroyed S. aureus and S. albus with equal facility. Although most experiments were carried out in the presence of 50 microg. streptomycin/ml., similar results were obtained without the use of this antibiotic. The applications of the tissue culture procedure with regard to studies on virulence and immunity in staphylococcal disease are discussed.
Involvement of membrane proteins and ion channels on the self‐rotation of human cells in a non‐rotating AC electric field (2015)

Dielectrophoresis is a force that has been exploited in microsystems for label-free characterization and separation of cells, when their electrical signature is known. However, the polarization effect of cells at the transmembrane protein level is not well established. In this work, we have use the self-rotation effect of cells in a non-rotating field, known as the "Quincke effect," in order to measure the maximum rotation frequency (frotmax ) of different cell populations when modifying the composition of their membrane. We investigated the influence of active ionic transportation of membrane protein concentration on frotmax of HEK cells. Our results show that ionic transportation is responsible for the reduction of conductivity within the cytoplasm, which results in higher frotmax . However, the influence of the concentration of proteins in the membrane, achieved by silencing gene expression in cancer cells, changes significantly frotmax , which is not explained by the changes of ionic conductivity within the cell.
Cardioprotective role of S-nitrosylated hemoglobin from rbc (2016)

Nitric oxide (NO) is a potent mediator of blood vessel dilation and is released by several cell sources. Red blood cells (rbc) release NO when hemoglobin that has been S-nitrosylated at Cys93 of the β-chain (βCys93) transitions from the oxygenated form to the deoxygenated form. This transition occurs in response to reduced tissue oxygenation and is an important physiologic regulator of hypoxic vasodilation. In this issue of the JCI, Zhang and colleagues demonstrate that S-nitrosylation of hemoglobin at βCys93 is important for tissue oxygenation after cardiac injury. Mice harboring mutations that prevent S-nitrosylation of βCys93 had higher rates of morbidity and mortality following cardiac injury compared with WT; however, adaptive cardiac vascularization was increased in some mutant mice and reduced cardiac injury in these animals. The results of this study reveal a previously unexplored role of S-nitrosylated hemoglobin in cardioprotection.
Cardioprotective Effect of IGF-1 in Mouse with Adriamycin Induced Cardiomyopathy (2002)

Background and Objectives:The purpose of this study was to investigate the apoptotic pathway, and the effect and mechanism of IGF-1 (insulin like growth factor 1) as a therapeutic agent, in Adriamycin (ADR) induced cardiomyopathy. Materials and Methods:We divided 17 mice into ADR (n=6), ADR +IGF-1 (n=6) and saline (n=5) groups. The following were injected into the intraperitoneal cavity for the specified periods: 2.5 mg/kg of ADR every week for 6 weeks, 0.1 mg/kg of IGF-1 in the 5th and 6th weeks and 10 mL/kg of saline every week for 6 weeks. Transthoracic echocardiography, with a 15MHz linear array, was performed before and after injection of the drugs. A TUNEL assay and immunohistochemical staining for Bax, bcl-2, capase-8 and 9, and western blotting for Bax and bcl-2 were performed on the myocardium. Results:The fractional shortening decreased (38.5±3.2% before vs. 29.2±5.5% after, p<0.05) and the left ventricular end systolic dimension increased (2.5±0.3 mm before vs. 3.1±0.5 mm after, p<0.05) following the injection of the ADR, but there were no interval changes in the mice treated with saline or ADR+IGF-1. The TUNEL assay showed a higher apoptotic index in the mice treated with ADR than in those treated with saline or ADR+IGF-1 (46± 8% in ADR, 0.1±0.03% in control, 22±5% in ADR+IGF-1, p<0.05). The immunohistochemical staining and western blot showed an increase in the expression of Bax, and a decrease in the expression of bcl-2 in the mice treated with ADR than in those treated with ADR+IGF-1 or saline. Conclusion:The apoptosis caused by the increased expression of Bax, and the decreased expression of bcl-2, was an important pathogenetic mechanism, and the IGF-1 prevents the progression of cardiomyopathy by attenuating the expressions of Bax and bcl-2 in ADR induced cardiomyopaththy. (Korean Circulation J 2002;32(12):1116-1123)
Resting State EEG Related to Mathematical Improvement After Spatial Training in Children (2021)

Spatial cognitive abilities, including mental rotation (MR) and visuo-spatial working memory (vsWM) are correlated with mathematical performance, and several studies have shown that training of these abilities can enhance mathematical performance. Here, we investigated the behavioral and neural correlates of MR and vsWM training combined with number line (NL) training. Fifty-seven children, aged 6–7, performed 25 days of NL training combined with either vsWM or MR and participated in an Electroencephalography (EEG)-session in school to measure resting state activity and steady-state visual evoked potentials during a vsWM task before and after training. Fifty children, aged 6–7, received usual teaching and acted as a control group. Compared to the control group, both training groups improved on a combined measure of mathematics. Cognitive improvement was specific to the training. Significant pre-post changes in resting state-EEG (rs-EEG), common to both training groups, were found for power as well as for coherence, with no significant differences in rs-EEG-changes between the vsWM and MR groups. Two of the common rs-EEG changes were correlated with mathematical improvement: (1) an increase in coherence between the central frontal lobe and the right parietal lobe in frequencies ranging from 16 to 25 Hz, and (2) an increase in coherence between the left frontal lobe and the right parietal lobe ranging from 23 to 25 Hz. These results indicate that changes in fronto-parietal coherence are related to an increase in mathematical performance, which thus might be a useful measure in further investigations of mathematical interventions in children.
Search for the Standard Model Higgs boson decay to μ+μ− with the ATLAS detector (2014)

A search is reported for Higgs boson decay to + -using data with an integrated luminosity of 24.8 fb -1 collected with the ATLAS detector in pp collisions at s = 7 and 8 TeV at the CERN Large Hadron Collider. The observed dimuon invariant mass distribution is consistent with the Standard Model background-only hypothesis in the 120-150 GeV search range. For a Higgs boson with a mass of 125.5 GeV, the observed (expected) upper limit at the 95% confidence level is 7.0 (7.2) times the Standard Model expectation. This corresponds to an upper limit on the branching ratio BR(H + -) of 1.5 10 -3 .
In Vitro Activity of Propolis on Oral Microorganisms and Biofilms (2021)

Natural products are being discussed as alternatives to commonly used chemicals in antimicrobial therapy. The study aimed to investigate the antimicrobial activity of propolis against microbial species associated with caries, periodontal disease, and Candida infections. Two commercially available ethanolic extracts of Brazilian and one of European propolis (EEP) were used. The minimal inhibitory concentrations (MIC) of propolis and controls against eight microbial strains were determined. Scanning and transmission electron microscopy (SEM and TEM) images visualized the effect of propolis on microorganisms. Subsequently, the activity on three different multi-species biofilms (both formation and existing biofilms) was assessed. All MIC values of the Brazilian EEPs were low against the tested oral species (≤0.1 mg/mL-3.13 mg/mL propolis (<i>Candida albicans</i>)). The European EEP had slightly higher MICs than the Brazilian EEPs. The SEM and TEM images suggest an interaction of propolis with the microbial cell wall. The European EEP exhibited the strongest effect on retarding biofilm formation, whereas the Brazilian EEPs were highly active against preformed biofilms (100 mg/mL propolis of both EEPs reduced colony forming unit counts always by more than 6 log10). The antimicrobial and anti-biofilm activities point to the potential of propolis as an adjunct in oral health care products.
Chemical Functionalization of Bioceramics To Enhance Endothelial Cells Adhesion for Tissue Engineering (2012)

To control the selective adhesion of human endothelial cells and human serum proteins to bioceramics of different compositions, a multifunctional ligand containing a cyclic arginine-glycine-aspartate (RGD) peptide, a tetraethylene glycol spacer, and a gallate moiety was designed, synthesized, and characterized. The binding of this ligand to alumina-based, hydroxyapatite-based, and calcium phosphate-based bioceramics was demonstrated. The conjugation of this ligand to the bioceramics induced a decrease in the nonselective and integrin-selective binding of human serum proteins, whereas the binding and adhesion of human endothelial cells was enhanced, dependent on the particular bioceramics.
Correlation trends in Naval Surface Warfare Center Panama City Division’s database of simulated and collected target scattering responses focused on automated target recognition (2015)

In recent years, NSWC PCD has assembled a database of sonar scattering responses encompassing a variety of objects including UXO, cylindrical shapes, and other clutter-type objects deployed on underwater sand and mud sediments and inspected over a large range of aspect angles and frequencies. Data available on these objects consist of a simulated component generated with 3D finite element calculations coupled to a fast Helmholtz-equation-based propagation scheme, a well-controlled experimental component collected in NSWC PCD’s pond facilities, and a component of measurements in realistic underwater environments off Panama City, FL (TREX13 and BayEX14). The goal is to use the database to test schemes for automating reliable separation of these objects into desired classes. Here, we report trends observed in an on-going correlation analysis of the database projected onto the target aspect vs frequency plane to clarify the roles of the environment, the data collection process, and target characteristics in identifying suitable phenomena useful for classification. [Work supported by ONR and SERDP.]
ClustTour (2010)

We present a technical demonstration of an online city exploration application that helps users identify interesting spots in a city by use of photo clusters corresponding to landmarks and events. Our application, called ClustTour, is based on an efficient landmark and event detection scheme for tagged photo collections. The proposed scheme relies on the combination of a graph-based photo clustering algorithm, making use of both visual and tag information of photos, with a cluster classification and merging module. ClustTour creates a map-based visualization of the identified photo clusters that are classified in prominent categories and are filterable by time and tag. We believe that such an application can greatly facilitate the task of knowing a city through its landmarks and events. So far, the demo has been based on a large photo dataset focused on Barcelona, and it is gradually expanding to contain photo clusters of several major cities of Europe. Furthermore, an Android application is developed that complements the web-based version of ClustTour.
In vitro activity of gemifloxacin (SB 265805; LB20304a) against human mycoplasmas (2000)

The in vitro activity of gemifloxacin, a new broad-spectrum fluoroquinolone, was compared with those of ciprofloxacin, erythromycin, azithromycin and doxycycline against 29 human respiratory or urogenital tract mycoplasmas. Gemifloxacin was highly active against all of the mycoplasma and ureaplasma species tested (MIC range 0.001-0.25 mg/L) and was 5- to 100-fold more active than ciprofloxacin. Doxycycline was less active than gemifloxacin against the mycoplasmas (MIC range 0.01-1 mg/L) but had similar activity against Ureaplasma urealyticum (MIC ranges 0.025-0.25 mg/L and 0.1-0. 25 mg/L, respectively). The macrolides, particularly azithromycin, were more active than gemifloxacin against Mycoplasma pneumoniae (MIC range 0.001-0.0025 mg/L) and Mycoplasma genitalium (0.0005-0. 001 mg/L) isolates but were less active against Mycoplasma fermentans and U. urealyticum and inactive against Mycoplasma hominis. Gemifloxacin may therefore be useful in the treatment of respiratory, urogenital or systemic mycoplasma infections in humans.
Phosphatase inhibition increases AQP2 accumulation in the rat IMCD apical plasma membrane (2016)

Vasopressin triggers the phosphorylation and apical plasma membrane accumulation of aquaporin 2 (AQP2), and it plays an essential role in urine concentration. Vasopressin, acting through protein kinase A, phosphorylates AQP2. However, the phosphorylation state of AQP2 could also be affected by the action of protein phosphatases (PPs). Rat inner medullas (IM) were incubated with calyculin (PP1 and PP2A inhibitor, 50 nM) or tacrolimus (PP2B inhibitor, 100 nM). Calyculin did not affect total AQP2 protein abundance (by Western blot) but did significantly increase the abundances of pS256-AQP2 and pS264-AQP2. It did not change pS261-AQP2 or pS269-AQP2. Calyculin significantly enhanced the membrane accumulation (by biotinylation) of total AQP2, pS256-AQP2, and pS264-AQP2. Likewise, immunohistochemistry showed an increase in the apical plasma membrane association of pS256-AQP2 and pS264-AQP2 in calyculin-treated rat IM. Tacrolimus also did not change total AQP2 abundance but significantly increased the abundances of pS261-AQP2 and pS264-AQP2. In contrast to calyculin, tacrolimus did not change the amount of total AQP2 in the plasma membrane (by biotinylation and immunohistochemistry). Tacrolimus did increase the expression of pS264-AQP2 in the apical plasma membrane (by immunohistochemistry). In conclusion, PP1/PP2A regulates the phosphorylation and apical plasma membrane accumulation of AQP2 differently than PP2B. Serine-264 of AQP2 is a phosphorylation site that is regulated by both PP1/PP2A and PP2B. This dual regulatory pathway may suggest a previously unappreciated role for multiple phosphatases in the regulation of urine concentration.
Progression of aortic stenosis and echocardiographic criteria for its severity (2020)

Our findings demonstrated gender- and race-related differences in AS progression and underscored the need to refine the multiparametric criteria for diagnosis of severe AS to minimize internal inconsistencies, which are high with the current cut-offs and amplified in patients with low stroke volumes.
Real-time concurrent collection on stock multiprocessors (2004)

We've designed and implemented a copying garbage-collection algorithm that is efficient, real-time, concurrent, runs on commercial uniprocessors and shared-memory multiprocessors, and requires no change to compilers. The algorithms uses standard virtual-memory hardware to detect references to "from space" objects and to synchronize the collector and mutator threads. We've implemented and measured a prototype running on SRC's 5-processor Firefly. It will be straightforward to merge our techniques with generational collection. An incremental, non-concurrent version could be implemented easily on many versions of Unix.