gebhart/patrepeval huggingface dataset:
Translational control in lysates of Drosophila melanogaster cells. (1981)

Cell-free protein-synthesizing systems made from Drosophila melanogaster cells were used to study the translational control induced in these cells by heat shock. Lysates of normally growing cells, termed 25 degrees C cells, translate both normal and heat shock mRNAs. Lysates of cells heat shocked at 36 degrees C for 1 hr, termed 36 degrees C cells, translate preferentially heat-shock mRNAs and a few 25 degrees C cell mRNAs. Thus, both lysates appear to reproduce the control displayed in vivo. Both lysates are optimally active at 28 degrees C, and all translations are done at that temperature, demonstrating that, once established, the discrimination system does not require heat-shock temperature for its activity. Addition of crude ribosome fractions from 25 degrees C cell lysates to lysates from heat-shocked cells "rescues" translation of 25 degrees C cell mRNA, which suggests that the discriminating elements are associated with ribosomes. Neither the heat-shock crude ribosome supplements nor the soluble fractions have any effect on either lysate. The experiments also show that RNA selection is determined by some feature of the RNA structure that is insensitive to protease digestion and phenol/chloroform extraction. The essential structural feature may not be unique to Drosophila mRNAs because the Drosophila lysate is capable of discriminating among mRNAs from other organisms.
Large-Scale Sprouting of Cortical Connections After Peripheral Injury in Adult Macaque Monkeys (1998)

Distributions of thalamic and cortical connections were investigated in four macaque monkeys with long-standing, accidental trauma to a forelimb, to determine whether the growth of new connections plays a role in the reorganization of somatosensory cortex that occurs after major alterations in peripheral somatosensory inputs. In each monkey, microelectrode recordings of cortical areas 3b and 1 demonstrated massive reorganizations of the cortex related to the affected limb. Injections of tracers in area 1 of these monkeys revealed normal patterns of thalamocortical connections, but markedly expanded lateral connections in areas 3b and 1. Thus, the growth of intracortical but not thalamocortical connections could account for much of the reorganization of the sensory maps in cortex.
General regularized classifiers (2007)

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Atrial Fibrillation Ablation (2009)

Due to the toxicities and limited efficacy of medical therapy, nonpharmacologic strategies for the management of atrial fibrillation in patients with heart failure are often employed. This chapter describes the techniques, clinical indications, and the devices utilized to perform catheter-based ablation of atrial fibrillation, including pulmonary vein isolation and left atrial substrate ablation.
Potassium and Sodium Content of California Wines (1979)

The sodium and potassium content of 132 white table, 75 rosé, 168 red table, 34 sherry, 6 white dessert and 13 ports of California was determined by flame emission photometry. The potassium values fell between 500 and 1300 mg/l. The sodium values were mainly below 100 mg/l. Only 10 of 428 wines contained more than 200 mg/l and six of these were from a single winery. The daily requirement for potassium is about 2 to 4 g and that of sodium 0.5 to 2.0 g. Wines are thus useful in the diet of individuals who must restrict sodium intake and maintain high potassium levels.
ChemInform Abstract: STEREOSPECIFIC SYNTHESIS OF CYCLIC ADENOSINE 3′,5′‐(SP)‐(18O)PHOSPHATE (1980)

Abstract Die Synthese der Titelverbindung (IV) erfolgt ausgehend von dem bekannten Cycloamidophosphat (I).
Effect of Incorporating Aromatic and Chiral Groups on the Dielectric Properties of Poly(dimethyltin esters) (2014)

High-dielectric constant materials are critical for numerous applications such as photovoltaics, photonics, transistors, and capacitors. There are numerous polymers used as dielectric layers in these applications but can suffer from having a low dielectric constant, small band gap, or ferroelectricity. Here, the structure-property relationship of various poly(dimethyltin esters) is described that look to enhance the dipolar and atomic polarization component of the dielectric constant. These polymers are also modeled using first principles calculations based on density functional theory (DFT) to predict such values as the total, electronic, and ionic dielectric constant as well as structure. A strong correlation is achieved between the theoretical and experimental values with the polymers exhibiting dielectric constants >4.5 with dissipation on the order of 10(-3) -10(-2) .
TCP tunnels: avoiding congestion collapse (2002)

This paper examines the attributes of TCP tunnels which are TCP circuits that carry IP packets and benefit from the congestion control mechanism of TCP/IP. The deployment of TCP tunnels reduces the many flows situation on the Internet to that of a few flows. TCP tunnels eliminate unnecessary packet loss in the core routers of the congested backbones which waste precious bandwidth leading to congestion collapse due to unresponsive UDP flows. We also highlight that the use of TCP tunnels can, in principle, help prevent certain forms of congestion collapse described by Floyd & Fall (see IEEE/ACM Transactions on Networking, vol.7, no.4, p.458-72, 1999). Using a testbed often Intel PCs running the Linux operating system and traffic generators simulating user applications, we explore: the benefits which TCP tunnels confer upon its payload of user IP traffic; the impact on the congestion within network backbones, and the protection that tunnels offer with respect to the various competing classes of traffic in terms of bandwidth allocation and reduced retransmissions. The deployment of TCP tunnels on the Internet and the issues involved are also discussed and we conclude that with the RFC2309 recommendation of using random early drop (RED) as the default packet-drop policy in Internet routers, coupled with the implementation of a pure tunnel environment on backbone networks makes the deployment of TCP tunnels a feasible endeavour worthy of further investigation.
Filtered x-ray diode diagnostics fielded on the Z accelerator for source power measurements (1999)

Filtered x-ray diode (XRD) detectors are used as primary radiation flux diagnostics on Sandia’s Z accelerator, which generates nominally a 200-TW, 2-MJ, x-ray pulse. Given such flux levels and XRD sensitivities the detectors are being fielded 23 m from the source. The standard diagnostic setup and sensitivities are discussed. Vitreous carbon photocathodes are being used to reduce the effect of hydrocarbon contamination present in the Z-machine vacuum system. Nevertheless pre- and postcalibration data taken indicate spectrally dependent changes in the sensitivity of these detectors by up to factors of 2 or 3.
Age-Associated Increased Interleukin-6 Gene Expression, Late-Life Diseases, and Frailty (2000)

Interleukin-6 (IL-6) is a proinflammatory cytokine that is normally tightly regulated and expressed at low levels, except during infection, trauma, or other stress. Among several factors that down-regulate IL-6 gene expression are estrogen and testosterone. After menopause or andropause, IL-6 levels are elevated, even in the absence of infection, trauma, or stress. IL-6 is a potent mediator of inflammatory processes, and it has been proposed that the age-associated increase in IL-6 accounts for certain of the phenotypic changes of advanced age, particularly those that resemble chronic inflammatory disease [decreased lean body mass, osteopenia, low-grade anemia, decreased serum albumin and cholesterol, and increased inflammatory proteins such as C-reactive protein (CRP) and serum amyloid A]. Furthermore, the age-associated rise in IL-6 has been linked to lymphoproliferative disorders, multiple myeloma, osteoporosis, and Alzheimer's disease. This overview discusses the data relating IL-6 to age-associated diseases and to frailty. Like the syndrome of inappropriate antidiuretic hormone, it is possible that certain clinically important late-life changes are due to an inappropriate presence of IL-6.
Structure and inhibition of herpesvirus DNA packaging terminase nuclease domain (2010)

During viral replication, herpesviruses package their DNA into the procapsid by means of the terminase protein complex. In human cytomegalovirus (herpesvirus 5), the terminase is composed of subunits UL89 and UL56. UL89 cleaves the long DNA concatemers into unit-length genomes of appropriate length for encapsidation. We used ESPRIT, a high-throughput screening method, to identify a soluble purifiable fragment of UL89 from a library of 18,432 randomly truncated ul89 DNA constructs. The purified protein was crystallized and its three-dimensional structure was solved. This protein corresponds to the key nuclease domain of the terminase and shows an RNase H/integrase-like fold. We demonstrate that UL89-C has the capacity to process the DNA and that this function is dependent on Mn(2+) ions, two of which are located at the active site pocket. We also show that the nuclease function can be inactivated by raltegravir, a recently approved anti-AIDS drug that targets the HIV integrase.
Ignition Sources In Room Fire Tests And Some Implications For Flame Spread Evaluation (1991)

Large scale room/corner fire test methods permit evaluation of the reaction to fire of wall and ceiling finish materials in configurations and under exposure conditions representative of end use. The response of a lining material depends directly on the exposure conditions imposed on the material, so selection of an appropriate ignition source intensity and location is essential for realistic appraisal of fire performance. A number of experiments have been conducted to evaluate the effects of heat release rate and ignition source location on the heat flux distribution imposed on lining materials in room/corner fire tests. Results of these experiments are reported and some implications for room/corner fire test methods and for flame spread prediction are discussed.
Structural and electrical anisotropy of (001)-, (116)-, and (103)-oriented epitaxial SrBi2Ta2O9 thin films on SrTiO3 substrates grown by pulsed laser deposition (2000)

Epitaxial SrBi2Ta2O9 (SBT) thin films with well-defined (001), (116), and (103) orientations have been grown by pulsed laser deposition on (001)-, (011)-, and (111)-oriented Nb-doped SrTiO3 substrates. X-ray diffraction pole figure and φ-scan measurements revealed that the three-dimensional epitaxial orientation relation SBT(001)‖SrTiO3(001), and SBT[11̄0]‖SrTiO3[100] is valid for all cases of SBT thin films on SrTiO3 substrates, irrespective of their orientations. Atomic force microscopy images of the c-axis-oriented SBT revealed polyhedron-shaped grains showing spiral growth around screw dislocations. The terrace steps of the c-axis-oriented SBT films were integral multiples of a quarter of the lattice parameter c of SBT (∼0.6 nm). The grains of (103)-oriented SBT films were arranged in a triple-domain configuration consistent with the symmetry of the SrTiO3(111) substrate. The measured remanent polarization (2Pr) and coercive field (2Ec) of (116)-oriented SBT films were 9.6 μC/cm2 and 168 kV/cm, respectively, for a maximum applied electric field of 320 kV/cm. Higher remanent polarization (2Pr=10.4 μC/cm2) and lower coercive field (2Ec=104 kV/cm) than those of SBT(116) films were observed in (103)-oriented SBT thin films, and (001)-oriented SBT revealed no ferroelectricity along the [001] axis. The dielectric constants of (001)-, (116)-, and (103)-oriented SBT were 133, 155, and 189, respectively.
Efficient ECG data compression and transmission algorithm for telemedicine (2016)

This paper presents an efficient electrocardiogram (ECG) data compression and transmission algorithm based on discrete wavelet transform and run length encoding. The proposed algorithm provides comparatively high compression ratio and low percent root-mean-square difference values. 48 records of ECG signals are taken from MIT-BIH arrhythmia database for performance evaluation of the proposed algorithm. Each record of ECG signals are of duration one minute and sampled at sampling frequency of 360 Hz over 11-bit resolution. Discrete wavelet transform has been used by means of linear orthogonal transformation of original signal. Using discrete wavelet transform, signal can be analyzed in time and frequency domain both. It also preserves the local features of the signal very well. After thresholding and quantization of wavelet transform coefficients, signals are encoded using run length encoding which improves compression significantly. The proposed algorithm offers average values of compression ratio, percentage root mean square difference, normalized percentage root mean square difference, quality score and signal to noise ratio of 44.0, 0.36, 5.87, 143, 3.53 and 59.52 respectively over 48 records of ECG data.
Machine Learning Meets Computation and Communication Control in Evolving Edge and Cloud: Challenges and Future Perspective (2019)

Mobile Edge Computing (MEC) is considered an essential future service for the implementation of 5G networks and the Internet of Things, as it is the best method of delivering computation and communication resources to mobile devices. It is based on the connection of the users to servers located on the edge of the network, which is especially relevant for real-time applications that demand minimal latency. In order to guarantee a resource-efficient MEC (which, for example, could mean improved Quality of Service for users or lower costs for service providers), it is important to consider certain aspects of the service model, such as where to offload the tasks generated by the devices, how many resources to allocate to each user (specially in the wired or wireless device-server communication) and how to handle inter-server communication. However, in the MEC scenarios with many and varied users, servers and applications, these problems are characterized by parameters with exceedingly high levels of dimensionality, resulting in too much data to be processed and complicating the task of finding efficient configurations. This will be particularly troublesome when 5G networks and Internet of Things roll out, with their massive amounts of devices. To address this concern, the best solution is to utilize Machine Learning (ML) algorithms, which enable the computer to draw conclusions and make predictions based on existing data without human supervision, leading to quick near-optimal solutions even in problems with high dimensionality. Indeed, in scenarios with too much data and too many parameters, ML algorithms are often the only feasible alternative. In this paper, a comprehensive survey on the use of ML in MEC systems is provided, offering an insight into the current progress of this research area. Furthermore, helpful guidance is supplied by pointing out which MEC challenges can be solved by ML solutions, what are the current trending algorithms in frontier ML research and how they could be used in MEC. These pieces of information should prove fundamental in encouraging future research that combines ML and MEC.
First-Principles Study of Sr2Fe2-xMoxO6 (SFMO) for Solid Oxide Fuel Cell Applications (2011)

Abstract not Available.
Efficiency of dispersive wave generation in dual concentric core microstructured fiber (2015)

We describe the generation of powerful dispersive waves that are observed when pumping a dual concentric core microstructured fiber by means of a sub-nanosecond laser emitting at a wavelength of 1064&#xA0;nm. The presence of three zeros in the dispersion curve, their spectral separation from the pump wavelength, and the complex dynamics of solitons originated by the pump pulse breakup all contribute to boost the amplitude of the dispersive wave on the long-wavelength side of the pump. The measured conversion efficiency toward the dispersive wave at 1548&#xA0;nm is as high as 50%. Our experimental analysis of the output spectra is completed by the acquisition of time delays of the different spectral components. Numerical simulations and an analytical perturbative analysis identify the central wavelength of the redshifted pump solitons and the dispersion profile of the fiber as the key parameters for determining the efficiency of the dispersive wave generation process.
UTPlaceF: a routability-driven FPGA placer with physical and congestion aware packing (2016)

FPGA packing and placement without routability consideration could lead to unroutable results for high-utilization designs. Conventional FPGA packing and placement approaches are shown to have severe difficulties to yield good routability. In this paper, we propose a FPGA packing and placement engine called UTPlaceF that simultaneously optimizes wirelength and routablity. A novel physical and congestion aware packing alogrithm and several congestion aware detailed placement techniques are proposed. Compared with the top 3 winners of ISPD'16 FPGA placement contest, UTPlaceF can achieve 3.3%, 7.7% and 28.3% better routed wirelength with similar or shorter runtime.
Antigen-induced B lymphocyte differentiation. (1982)

The analysis of B-lymphocyte activation has been a tantalizing prospect for both immunologists and cell biologists, as B cells have the unique characteristics of possessing a well-characterized receptor and displaying a clear inducible response to a specific antigen. As outlined in this review, we now know much about the cellular events which occur when mature B cell encounters antigen within the peripheral lymphoid organ of an immunocompetent host. Our understanding of the molecular events associated with these cellular processes is currently limited, but such information will undoubtedly ensue. The greatest challenges remaining in B-cell immunology are immunoregulation and an understanding of how the enormous B-cell specificity repertoire is generated. These challenges require greater insight into lymphocyte triggering events and the early events in B-cell maturation. This review has not restricted itself to the phenomena associated with antigen-triggered mature splenic B cells, but has attempted to include aspects of B-cell development which are often overlooked or disregarded. In particular, attention has been drawn to certain nonspecific antigen-induced B-cell events, and to antigen-initiated developmental processes which precede mature B-cell development. Additionally, the commitment of triggered mature B cells to effector cell production has been reconsidered in light of current attempts to propagate normal lymphocytes continuously and in a manner which avoids terminal differentiation. The availability of such lines, together with increasingly refined technology, will hopefully allow us to resolve the remaining mysteries in B-cell development.
On the Behavior of Fiberglass Epoxy Composites under Low Velocity Impact Loading (2010)

Response of fiberglass epoxy composite laminates under low velocity impact loading is investigated using LS-DYNA®, and the results are compared with experimental analysis performed using an instrumented impact test setup (Instron dynatup 8250). The composite laminates are manufactured using H-VARTM© process with basket weave E-Glass fabrics. Epon 862 is used as a resin system and Epicure-W as a hardening agent. Composite laminates, with 10 layers of fiberglass fabrics, are modeled using 3D solid elements in a mosaic fashion to represent basket weave pattern. Mechanical properties are calculated by using classical micromechanical theory and assigned to the elements using ORTHOTROPIC ELASTIC material model. The damage occurred since increasing impact energy is incorporated using ADVANCED COMPOSITE DAMAGE material model in LS-DYNA®. Good agreements are obtained with the failure damage results in LS-DYNA® and experimental results. Main considerations for comparison are given to the impact load carrying capacity and the amount of impact energy absorbed by the laminates.
Detector-device-independent quantum key distribution: Security analysis and fast implementation (2016)

One of the most pressing issues in quantum key distribution (QKD) is the problem of detector side-channel attacks. To overcome this problem, researchers proposed an elegant “time-reversal” QKD protocol called measurement-device-independent QKD (MDI-QKD), which is based on time-reversed entanglement swapping. However, MDI-QKD is more challenging to implement than standard point-to-point QKD. Recently, an intermediary QKD protocol called detector-device-independent QKD (DDI-QKD) has been proposed to overcome the drawbacks of MDI-QKD, with the hope that it would eventually lead to a more efficient detector side-channel-free QKD system. Here, we analyze the security of DDI-QKD and elucidate its security assumptions. We find that DDI-QKD is not equivalent to MDI-QKD, but its security can be demonstrated with reasonable assumptions. On the more practical side, we consider the feasibility of DDI-QKD and present a fast experimental demonstration (clocked at 625 MHz), capable of secret key exchange up to more than 90 km.
Bright Stretchable Alternating Current Electroluminescent Displays Based on High Permittivity Composites (2016)

A high permittivity composite is developed to enhance the brightness of stretchable electroluminescent displays. The unique two-step assembly process yields dense layers, in which the voids around the electroluminescent particles are filled with smaller high dielectric particles. A stretchable seven-segment display based on the composite is bright enough to be used under standard indoor lighting conditions.
Prediction of oxygen consumption rates from heart interval mean and variance (2002)

Heart interval mean and variance were compared as predictors of waking oxygen consumption rate in 20 adult subjects. Correlations between O/sub 2/ consumption and mean heart intervals were significantly better than heart interval variance during both sedentary (P=0.01) and active (P<0.001) periods.
A Single Channel Speech Enhancement for Automatic Speech Recognition (2011)

This paper describes a single channel speech enhancement as the pre-processor of automatic speech recognition system. The improvements are based on using optimally modified log-spectra (OM-LSA) gain function with a non-causal a priori signal-to-noise ratio (SNR) estimation. Experimental results show that the proposed method gives better perceptual evaluation of speech quality score (PESQ) and lower log-spectral distance, and also better word accuracy. In the enhancement system, parameters was turned for automatic speech recognition.