gebhart/patrepeval huggingface dataset:
An MR-compatible singles detection and processing unit for simultaneous preclinical PET/MR (2012)

Improving PET performance towards higher resolution and better sensitivity resulted in a continuous trend - especially in solid state PET and PET/MR - of an increasing number of channels to be read out by the detector electronics. Building complete PET systems with these detectors calls for a modular and self-triggered architecture with distributed processing power that is already in the detector module able to condense the data stream to corrected and gated singles.
Determination of Gurson–Tvergaard–Needleman Model Parameters for Failure of a Polymeric Material (2010)

In this work, the Gurson–Tvergaard–Needleman model, commonly used for metallic materials, is applied to the failure of a polymeric material – specifically a polyethylene carbon monoxide copolymer, which is an enhanced photodegradable material. Gurson–Tvergaard–Needleman model parameters for this material are obtained using the Nelder–Mead simplex method when correlating experimental and numerical results of both tensile and fracture specimens. Results show that the Gurson–Tvergaard–Needleman model can also be used for polymeric materials with selection of proper parameters that are quite different from the ones proposed for metallic materials.
Supplementary Fig. S2 from Targeting a metalloprotease-PAR1 signaling system with cell-penetrating pepducins inhibits angiogenesis, ascites, and progression of ovarian cancer (2023)

Supplementary Fig. S2 from Targeting a metalloprotease-PAR1 signaling system with cell-penetrating pepducins inhibits angiogenesis, ascites, and progression of ovarian cancer
ChemInform Abstract: GLYCOSIDE DES PYRAZOLS UND KONDENSIERTER PYRAZOL‐HETEROCYCLEN 2. MITT. SYNTHESE VON GLYCOSIDEN DES PYRAZOLO(3,4‐B)PYRIDINS (1973)

Abstract Durch Kondensation von 1‐O‐Acetyl‐2,3,5‐tri‐O‐benzoyl‐ribofuranose mit 4‐ Chlor‐ bzw. 4‐Methylmercapto‐pyrazolo‐[3,4‐b]‐pyridin bei 160°C und nachfolgend Debenzoylierung mit siedendem methanolischem Na‐methylat werden die β‐D‐Ribofuranosyl‐pyrazolopyridine (I) dargestellt.
The spa2-related protein, sph1p, is important for polarized growth in yeast (1998)

The Saccharomyces cerevisiae protein Sph1p is both structurally and functionally related to the polarity protein, Spa2p. Sph1p and Spa2p are predicted to share three 100-amino acid domains each exceeding 30% sequence identity, and the amino-terminal domain of each protein contains a direct repeat common to Homo sapiens and Caenorhabditis elegans protein sequences. sph1- and spa2-deleted cells possess defects in mating projection morphology and pseudohyphal growth. sph1(Delta) spa2(Delta) double mutants also exhibit a strong haploid invasive growth defect and an exacerbated mating projection defect relative to either sph1(Delta) or spa2(Delta) single mutants. Consistent with a role in polarized growth, Sph1p localizes to growth sites in a cell cycle-dependent manner: Sph1p concentrates as a cortical patch at the presumptive bud site in unbudded cells, at the tip of small, medium and large buds, and at the bud neck prior to cytokinesis. In pheromone-treated cells, Sph1p localizes to the tip of the mating projection. Proper localization of Sph1p to sites of active growth during budding and mating requires Spa2p. Sph1p interacts in the two-hybrid system with three mitogen-activated protein (MAP) kinase kinases (MAPKKs): Mkk1p and Mkk2p, which function in the cell wall integrity/cell polarization MAP kinase pathway, and Ste7p, which operates in the pheromone and pseudohyphal signaling response pathways. Sph1p also interacts weakly with STE11, the MAPKKK known to activate STE7. Moreover, two-hybrid interactions between SPH1 and STE7 and STE11 occur independently of STE5, a proposed scaffolding protein which interacts with several members of this MAP kinase module. We speculate that Spa2p and Sph1p may function during pseudohyphal and haploid invasive growth to help tether this MAP kinase module to sites of polarized growth. Our results indicate that Spa2p and Sph1p comprise two related proteins important for the control of cell morphogenesis in yeast.
Enhanced Collagen Type IV Based Differentiation of Embryonic Stem Cells Towards Flk‐1 Expressing Vascular Progenitors by the Wnt/β‐Catenin Synergist QS11 (2011)

Abstract Mouse embryonic stem (mES) cells when plated onto collagen type IV in the presence of serum‐containing medium differentiate into a mixed cell population that contains low levels of Flk‐1 expressing vascular progenitor cells. When isolated and re‐plated onto collagen type IV, Flk‐1+ cells further differentiate into PECAM1+ endothelial and SMA+ mural cells. However, the low abundance and transient nature by which Flk‐1+ cells are generated during embryonic stem (ES) cell differentiation presents limitations in case large numbers of Flk‐1+ cells or its derivates are to be obtained. To optimize Flk‐1 progenitor induction from undifferentiated mES cells, the effects of QS11, a small organic molecule that synergistically activates canonical Wnt signalling, were investigated. In the presence of QS11 the percentage of Flk‐1+ cells in differentiating cultures of mES cells increases 1.5 fold. Furthermore, QS11 enhances cell proliferation in differentiating mES cells that results in a 2 fold increase in cell numbers when Flk‐1 induction is maximal. The combined effects of QS11 on differentiation and proliferation increase the efficiency by which Flk‐1 progenitors can be generated by approximately 300%, thereby providing a novel tool for vascular progenitor cell production for use in fundamental research and applications such as tissue engineering.
Electroactive polymer (EAP) actuators as artificial muscles : reality, potential, and challenges (2001)

In concept and execution, this book covers the field of EAP with careful attention to all its key aspects and full infrastructure, including the available materials, analytical models, processing techniques, and characterization methods. In this second edition the reader is brought current on promising advances in EAP that have occurred in electric EAP, electroactive polymer gels, ionomeric polymer-metal composites, carbon nanotube actuators, and more
Long-Term Outcomes of Renal Tumor Radio Frequency Ablation Stratified by Tumor Diameter: Size Matters (2012)

Radio frequency ablation treatment success of the small renal mass is strongly correlated with tumor size. Radio frequency ablation provides excellent and durable outcomes, particularly in tumors smaller than 3 cm. Of tumors 3 cm or larger, approximately 20% will recur such that alternative treatment techniques should be considered. However, most treatment failures are local and are often successfully treated with another ablation session.
Reducing informational masking by sound segregation (1994)

Informational masking was reduced using three stimulus presentation schemes that were intended to perceptually segregate the signal from the masker. The maskers were sets of sinusoids chosen randomly in frequency and intensity on each stimulus interval or, in some conditions, on every masker burst in a series of bursts within intervals. Masker components were excluded from the frequency region surrounding the 1000-Hz signal to minimize the energetic masking. Masked thresholds as great as 60-70 dB above quiet threshold were observed for some subjects in some conditions. It was shown that this informational masking could be reduced as much as 40 dB by: (1) presenting the masker to both ears and signal to one ear; (2) playing different masker samples sequentially in each interval of every trial; or (3) presenting the signal in alternate bursts of multiple, identical masker samples. For the binaural manipulation, informational masking was reduced because the masker and signal were perceived as originating from different interaural locations. In the latter two manipulations, a difference in the spectral or temporal pattern of the signal and masker provided the detection cue. These effects were interpreted as evidence of the importance of perceptual segregation of sounds in noisy listening environments where signal reception is not limited by energetic masking.
An optical comparison of concentrating solar collectors (1980)

This item was digitized from a paper original and/or a microfilm copy. If you need higher-resolution images for any content in this item, please contact us at repository@u.library.arizona.edu.
Factors Affecting the Use of Reforested Sites by Reptiles in Cleared Rainforest Landscapes in Tropical and Subtropical Australia (2006)

Abstract Despite recent efforts to reforest cleared rainforest landscapes, in Australia and elsewhere, the value of reforested sites for rainforest‐dependent reptiles is unknown. We surveyed the occurrence of reptiles in a range of reforestation types (monoculture and mixed‐species timber plantations, diverse “ecological restoration” plantings and regrowth), as well as reference sites in pasture and rainforest, in tropical and subtropical Australia. We recorded 29 species of reptiles from 104 sites, including 15 rainforest‐dependent species. Most rainforest reptiles were strongly associated with complex microhabitats (tree trunks, logs, rocks). The richness and abundance of rainforest‐dependent reptiles varied between the different types of reforestation and between regions. In the tropics, rainforest reptiles were recorded in old timber plantations and ecological restoration plantings but not in young timber plantations or regrowth. Rainforest reptiles were recorded in few reforested sites in the subtropics. The occurrence of rainforest‐dependent reptiles in reforested sites appears to be influenced by (1) habitat structure; (2) proximity to source populations in rainforest; and (3) biogeography and historical differences in the extent of rainforest. Restoration of cleared land for rainforest‐dependent reptiles may require the development, or deliberate creation, of complex structural attributes and microhabitats in reforested sites. Where reforested sites are located away from rainforest, recolonization by rainforest reptiles may require the construction of corridors of suitable habitat between reforested sites and rainforest or the translocation of reptiles to reforested sites.
Surface enhanced infrared spectroscopy using gold nanoantennas (2010)

Abstract The sensitivity of infrared (IR) vibration spectroscopy can be enhanced by several orders of magnitude if plasmonic electromagnetic nearfield enhancement is exploited. For maximum enhancement the plasmonic resonance needs to be strong, which cannot be achieved by randomly grown metal island films that on average may show already signal enhancement of the order of 1000. Metal nanowires may give sufficiently strong antenna‐like plasmonic resonances in the IR that can be adjusted to the molecular vibration frequencies of interest via the wire length. With individual gold nanowires we obtained vibration‐signal enhancement up to 500,000 for molecular monolayers adsorbed on gold nanowires. The already obtained enhancement is not a limit. Since antennae coupled via nanogaps should enable strong electromagnetic nearfield enhancement in these gaps, respective arrays would be ideal for surface enhanced IR spectroscopy. First experiments prove the tendency of increasing vibration‐signal enhancement with decreasing gap size.
Crystal structure of ( Z )-cefprozil monohydrate, C 18 H 19 N 3 O 5 S(H 2 O) (2019)

The crystal structure of cefprozil monohydrate has been solved and refined using synchrotron X-ray powder diffraction data and optimized using density functional techniques. Cefprozil monohydrate crystallizes in space group P 2 1 (#4) with a = 11.26513(6), b = 11.34004(5), c = 14.72649(11) Å, β = 90.1250(4)°, V = 1881.262(15) Å 3 , and Z = 4. Although a reasonable fit was obtained using an orthorhombic model, closer examination showed that many peaks were split and/or had shoulders, and thus the true symmetry was monoclinic. DFT calculations revealed that one carboxylic acid proton moved to an amino group. The structure thus contains one ion pair and one pair of neutral molecules. This protonation was confirmed by infrared spectroscopy. There is an extensive array of hydrogen bonds resulting in a three-dimensional network. The powder pattern has been submitted to ICDD ® for inclusion in the Powder Diffraction File™.
Environmental Screening of <em>Aeromonas hydrophila</em>, <em>Mycobacterium</em> spp., and <em>Pseudocapillaria tomentosa</em> in Zebrafish Systems (2017)

Health monitoring systems are developed and used in zebrafish research facilities because pathogens of Danio rerio such as Aeromonas hydrophila, Mycobacterium spp., and Pseudocapillaria tomentosa have the potential to impair animal welfare and research. The fish are typically analyzed post mortem to detect microbes. The use of sentinels is a suggested way to improve the sensitivity of the surveillance and to reduce the number of animals to sample. The setting of a pre-filtration sentinel tank out of a recirculating system is described. The technique is developed to prevent water pollution and to represent the fish population by a careful selection of age, gender, and strains. In order to use the minimum number of animals, techniques to screen the environment are also detailed. Polymerase Chain Reaction (PCR) on surface sump swabs is used to significantly improve the detection of some prevalent and pathogenic mycobacterial species such as Mycobacterium fortuitum, Mycobacterium haemophilum, and Mycobacterium chelonae. Another environmental method consists of processing the sludge at the bottom of a holding tank or sump to look for P. tomentosa eggs. This is a cheap and fast technique that can be applied in quarantine where a breeding device is submerged into the holding tank of imported animals. Finally, PCR is applied to the sludge sample and A. hydrophila is detected at the sump's bottom and surface. Generally, these environmental screening techniques applied to these specific pathogens have led to an increased sensitivity compared to the testing of pre-filtration sentinels.
Method for Measuring Rates of NH 4 + Turnover in Anoxic Marine Sediments, Using a 15 N-NH 4 + Dilution Technique (1979)

A method is described for the determination of the net and total rates of NH(4) production and NH(4) incorporation at different depths in an anoxic marine sediment. N-NH(4) was added to the sediment NH(4) pool, and the N content was assayed after 0, 2, and 5 days of incubation. The pool size changed during incubation; this change in pool size is incorporated into a model which predicts the dynamics of N-NH(4) dilution. A simple microdiffusion of NH(3) was followed by an emission spectrometry analysis of N content. This procedure avoided all problems of cross-contamination. The model was tested and rates were measured in four sediment cores, at seven different depths. The high correlation coefficients (mean, 0.96 for the 0- to 2-, 2- to 4-, 4- to 6-, and 6- to 8-cm sediment fractions) indicated that the model was correct and that the measured rates were valid. The immediate distribution of N-NH(4) between interstitial and exchangeable NH(4) pools indicated that it was the combined pool that was turning over. In the 0- to 2-cm fraction at 17 degrees C the net rate of NH(4) production was 274 (standard deviation, 31) nmol cm day, and the mean total rate of NH(4) production was 309 (standard deviation, 39) nmol cm day; both rates decreased to <1% of these values in the 12- to 14-cm fractions.
Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development (2017)

Despite the importance of cell fusion for mammalian development and physiology, the factors critical for this process remain to be fully defined, which has severely limited our ability to reconstitute cell fusion. Myomaker (Tmem8c) is a muscle-specific protein required for myoblast fusion. Expression of myomaker in fibroblasts drives their fusion with myoblasts, but not with other myomaker-expressing fibroblasts, highlighting the requirement of additional myoblast-derived factors for fusion. Here we show that Gm7325, which we name myomerger, induces the fusion of myomaker-expressing fibroblasts. Thus, myomaker and myomerger together confer fusogenic activity to otherwise non-fusogenic cells. Myomerger is skeletal muscle-specific and genetic deletion in mice results in a paucity of muscle fibres demonstrating its requirement for normal muscle formation. Myomerger deficient myocytes differentiate and harbour organized sarcomeres but are fusion-incompetent. Our findings identify myomerger as a fundamental myoblast fusion protein and establish a system that begins to reconstitute mammalian cell fusion.
Two‐Photon‐Induced Fluorescence in New π‐Expanded Diketopyrrolopyrroles (2014)

Structurally unique π-expanded diketopyrrolopyrroles (EDPP) were designed and synthesized. Strategic placement of a fluorene scaffold at the periphery of a diketopyrrolopyrrole through tandem Friedel-Crafts-dehydration reactions resulted in dyes with supreme solubility. The structure of the dyes was confirmed by X-ray crystallography verifying a nearly flattened arrangement of the ten fused rings. Despite the extended ring system, the dye still preserved good solubility and was further functionalized by using Pd-catalyzed coupling reactions, such as the Buchwald-Hartwig amination. Photophysical studies of these new functional dyes revealed that they possess enhanced properties when compared with expanded DPPs in terms of two-photon absorption cross-section. It is further demonstrated that in addition to the initial diacetals, the final electrophilic cyclization step can also be applied to diketones. By placing two amine groups at peripheral positions of the resulting dyes, values of two-photon absorption cross-section on the level of 2000 GM around 1000 nm were achieved, which in combination with high fluorescence quantum yield (Φfl ), generated a two-photon brightness of approximately 1600 GM. These characteristics in combination with strong red emission (665 nm) make these new π-expanded diketopyrrolopyrroles of major promise as two-photon dyes for bioimaging applications. Finally, the corresponding N-alkylated DPPs displayed a solid-state fluorescence.
A G‐box motif (GCCACGTGCC) tetramer confers high‐level constitutive expression in dicot and monocot plants (1999)

Summary GUS reporter expression from 11 basal promoters (CaMV –90) with G‐box cores (CACGTG) was analysed to evaluate the regulatory roles of G‐box flanking sequences. While most G‐box motifs exhibited some tissue preference of gene expression, a distinct tissue‐specific expression was not apparent. However, one of 11 G‐box sequences, the G‐box 10 (GCCACGTGCC) tetramer, conferred a high‐level constitutive expression in seed, root, leaf, axillary bud, almost all parts of flower buds and pollen of transgenic tobacco plants. Furthermore, the G‐box 10 tetramer promoter exhibited high‐level expression in transgenic dicot carrot and monocot rice. This is apparently the first report of a G‐box motif conferring a high‐level constitutive expression in a non‐tissue‐specific manner.
Glass direct bonding technology for hermetic seal package (2002)

A new SMD type hermetic seal package using glass wafers has been developed for SAW (surface acoustic wave) resonators. This package is composed of two glass wafers in which many cavities and through holes are formed. The SAW resonator chip is inserted into the cavity. Electrodes are led out from the through holes without using wire. Two glass wafers are directly bonded at the atomic level using no adhesive. This package technology realizes small size, low profile SMD type package whose size is the chip size plus 1.0 mm and whose height is 1.0 mm. The size of the glass package type SAW resonator is 4.0/spl times/2.0/spl times/1.0 mm. The area is 1/9 and the volume is 1/33 of the conventional CAN package. The frequency characteristics and reliability of the developed SAW resonators were checked. No degradation was observed by the packaging process. The insertion loss was reduced by wireless assembly. The change in the characteristics after high-temperature storage test was extremely small because no resin is used in the glass package.
Effect of Be Addition on the Precipitation Behaviors and Mechanical Properties in Al-Cu-Li-Mg-Zr-(Ag) Alloys (2005)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
The total synthesis of dihydrocrinine and related compounds (1966)

H. Irie, S. Uyeo and A. Yoshitake, Chem. Commun. (London), 1966, 635 DOI: 10.1039/C19660000635
Origins of the Complex Motion of Advancing Surfactant Solutions (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOrigins of the Complex Motion of Advancing Surfactant SolutionsB. Frank and S. GaroffCite this: Langmuir 1995, 11, 1, 87–93Publication Date (Print):January 1, 1995Publication History Published online1 May 2002Published inissue 1 January 1995https://pubs.acs.org/doi/10.1021/la00001a018https://doi.org/10.1021/la00001a018research-articleACS PublicationsRequest reuse permissionsArticle Views363Altmetric-Citations69LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Absorption Enhancement in “Giant” Core/Alloyed-Shell Quantum Dots for Luminescent Solar Concentrator (2016)

Luminescent solar concentrators (LSCs) can potentially reduce the cost of solar cells by decreasing the photoactive area of the device and boosting the photoconversion efficiency (PCE). This study demonstrates the application of “giant” CdSe/CdxPb1–xS core/shell quantum dots (QDs) as light harvesters in high performance LSCs with over 1.15% PCE. Pb addition is critical to maximize PCE. First, this study synthesizes “giant” CdSe/CdxPb1–xS QDs with high quantum yield (40%), narrow size distribution (<10%), and stable photoluminescence in a wide temperature range (100–300 K). Subsequently these thick alloyed-shell QDs are embedded in a polymer matrix, resulting in a highly transparent composite with absorption spectrum covering the range 300–600 nm, and are applied as active material for prototype LSCs. The latter exhibits a 15% enhancement in efficiency with respect to 1% PCE of the pure-CdS-shelled QDs. This study attributes this increase to the contribution of Pb doping. The results demonstrate a straightforward approach to enhance light absorption in “giant” QDs by metal doping, indicating a promising route to broaden the absorption spectrum and increase the efficiency of LSCs.