gebhart/patrepeval huggingface dataset:
Low temperature delays development of photosystem II activity in winter rye leaves (1989)

The ability of leaves to acclimate photosynthetically to low temperature was examined during leaf development in winter rye plants ( Secale cereale L. cv. Puma) grown at 20°C or at 6°C. All leaves grown at 6°C exhibit increased chlorophyll (Chl) levels per leaf area, higher rates of uncoupled, light‐saturated photosystem I (PSI) electron transport, and slower increases in photosystem II (PSII) electron transport capacity, when compared with 20°C leaves. The stoiehiometry of PSI and PSII was estimated for each leaf age class by quantifying Chl in elcctrophorctic separations of Chl‐protein complexes. The ratio of PSII/PSI electron transport in 20°C leaves is highly correlated with the ratio of core Chl a ‐proteins associated with PSII (CPa) to those associated with PSI (CP1). In contrast, PSII/PSI electron transport in 6°C leaves is not as well correlated with CPa/CP1 and is related, in part, to the amount and organization of light‐harvesting Chl a/b ‐proteins associated with PSII. CPa/CP1 increases slowly in 6°C leaves, although the ratio of CPa/CP1 in mature 20°C and 6°C leaves is not different. The results suggest that increased PSI activity at low temperature is not related to an increase in the relative proportion of PSI and may reflect, instead, a regulatory change. Photosynthetic acclimation to low environmental temperature involves increased PSI activity in mature leaves shifted to 6°C. In leaves grown entirely at 6°C, however, acclimation includes both increased PSI activity and modifications in the rate of accumlation of PSII and in the organization of LHCII.
Hydrogen-bonding tectons for the construction of bimolecular framework materials (2008)

Three hydrogen-bonding tectons functionalised with pyrimidine-dione hydrogen-bonding moieties, either uracil or thymine groups, have been synthesised and their solid-state structures studied by single crystal X-ray diffraction. The tectons have different linkers between the pyrimidine-dione hydrogen-bonding groups. Whereas tectons 1 and 2 have either naphthalenetetracarboxylic diimide or p-xylyl spacers, respectively, linking two hydrogen-bonding appendages, tecton 3 comprises three thymine moieties linked via a 2,4,6-tris(methyl)mesitylene spacer. All three tectons have been structurally characterised and in the case of 2 and 3 exhibit the anticipated R22(8) double hydrogen-bonded arrangement between the imide moieties. In contrast, the single crystal structure of the DMSO solvate of 1 does not exhibit inter-tecton hydrogen-bonding but adopts N–H⋯O interactions with guest DMSO molecules. However, bimolecular hydrogen-bonded adducts have successfully been prepared exploiting the complementary triple hydrogen-bonding interactions between 1, or 2, and melamine to give two-dimensional hydrogen-bonded sheets.
Steroids and hematopoiesis. III. The response of granulocytic and erythroid colony-forming cells to steroids of different classes (1976)

Selected androgenic and nonandrogenic steroids enhance in vitro granulocytic and erythroid colony formation by mouse marrow cells, but do so by influencing either different target cells or cells in different states of cell cycle. Etiocholanolone, a naturally occurring nonandrogenic testosterone metabolite, permits cells not in active cycle to respond to colony-stimulating factor or erythropoietin. Fluoxymesterone, a synthetic androgen, appears to enhance colony growth by increasing the responsiveness of target cells to tropic stimuli. The majority of cells responding to this androgen are in active DNA synthesis. Direct comparison, however, of etiocholanolone-dependent erythroid or granulocytic colony-forming cells demonstrates nonidentity of the target cells. Thus colony-forming units responding to different classes of steroids are in different states of cell cycle and are physically separable. The enhancement of the in vitro response of colony-forming cells to regulating hormones by steroids such as etiocholanolane suggests a mechanism by which such agents may be therapeutically effective in certain cases of marrow failure in man.
Chronic Inflammation From Polycarbonate Motility Peg Inhibits Osteogenesis in a Human Hydroxyapatite Orbital Implant (2005)

The histologic findings of a pegged hydroxyapatite orbital implant removed due to chronic inflammation and pain are described. A 44-year-old woman underwent explantation of a hydroxyapatite sphere and polycarbonate motility peg due to chronic redness, swelling, discharge, and pain. Histology revealed complete fibrovascularization of the implant, with approximately 90% ossification. No bone marrow was identified. Histologic sections revealed fibrous connective tissue at the periphery of a sclerotic bony mass with a granulomatous inflammatory infiltrate at the motility peg aperture. There were no bacterial, mycobacterial, or fungal organisms identified histologically or by culture. Consistent with previous reports, hydroxyapatite orbital implants are amenable to fibrovascular ingrowth and bony transformation. The presence of a granulomatous inflammatory reaction around the polycarbonate motility peg in this case may have prevented complete osseous transformation of the hydroxyapatite implant.
Solid‐Phase Synthesis of Heterocyclic Aromatics: Applicability Towards Combinatorial Chemistry (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
Reduced tumorigenicity of rat glioma cells in the brain when mediated by hygromycin phosphotransferase (2001)

The results indicate that HPT suppresses tumor formation. Three weeks after implantation, only 44% of animals implanted with C6R-G/H cells developed tumors, whereas all animals that received C6 glioma cells developed high-grade gliomas. The C6R-G/H cells filled a 20-fold smaller maximal cross-sectional area than the C6 cells, and exhibited less malignant characteristics, including reduced angiogenesis, mitosis, and cell proliferation. Similar results were obtained in the brain of nude rats, indicating that the immune system did not play a significant role in suppressing tumor growth. The combination of green fluorescent protein (GFP) and HPT was more effective in suppressing tumorigenesis than either plasmid by itself, indicating that the GFP may protect against inactivation of the HPT. Interestingly. hygromycin resistance was lost in tumor cells that were recovered from a group of animals in which C6R-G/H cells formed tumors, confirming the correlation of HPT with reduced tumorigenicity.
Scientific Committee on Health and Environmental Risks opinion on: Non surfactant Organic Ingredients and Zeolite-based Detergents (RPA report J480b/detergents – 30 June 2006) (2007)

Adopted by the SCHER during the 17th plenary of 29 May 2007
A single Danio rerio hars gene encodes both cytoplasmic and mitochondrial histidyl-tRNA synthetases (2017)

Histidyl tRNA Synthetase (HARS) is a member of the aminoacyl tRNA synthetase (ARS) family of enzymes. This family of 20 enzymes is responsible for attaching specific amino acids to their cognate tRNA molecules, a critical step in protein synthesis. However, recent work highlighting a growing number of associations between ARS genes and diverse human diseases raises the possibility of new and unexpected functions in this ancient enzyme family. For example, mutations in HARS have been linked to two different neurological disorders, Usher Syndrome Type IIIB and Charcot Marie Tooth peripheral neuropathy. These connections raise the possibility of previously undiscovered roles for HARS in metazoan development, with alterations in these functions leading to complex diseases. In an attempt to establish Danio rerio as a model for studying HARS functions in human disease, we characterized the Danio rerio hars gene and compared it to that of human HARS. Using a combination of bioinformatics, molecular biology, and cellular approaches, we found that while the human genome encodes separate genes for cytoplasmic and mitochondrial HARS protein, the Danio rerio genome encodes a single hars gene which undergoes alternative splicing to produce the respective cytoplasmic and mitochondrial versions of Hars. Nevertheless, while the HARS genes of humans and Danio differ significantly at the genomic level, we found that they are still highly conserved at the amino acid level, underscoring the potential utility of Danio rerio as a model organism for investigating HARS function and its link to human diseases in vivo.
Templated microwave synthesis of luminescent carbon nanofibers (2018)

Carbon based nanomaterials offer the potential to provide solutions to key technological challenges. This work describes the preparation of luminescent carbon nanofibers by template-assisted microwave pyrolysis of environmentally friendly precursors, citric acid and polyethyleneimine, in aqueous solution. SEM reveals a dense forest of vertically aligned cylindrical carbon nanofibers with an average diameter of <i>ca.</i> 200 nm, which are shown by TEM to be amorphous. Compositional analysis indicated the incorporation of amino and pyrrolic nitrogen, and carbon-oxygen moieties. These species contribute to UV light absorption with an absorption shoulder and tail towards visible wavelengths. UV excitation gave visible (blue) emission at <i>ca.</i> 450 nm with a quantum yield of <i>ca.</i> 5%; emission decay under pulsed excitation was predominantly mono-exponential with a lifetime of <i>ca.</i> 1 ns. The emission maximum is largely excitation wavelength independent suggesting the involvement of citrazinic acid-type functionalities in the fiber photophysics. Reversible pH-dependent excitation and emission behaviour was observed, with maximum emission at <i>ca.</i> pH 7. Nanofiber emission was also quenched in aqueous solutions of metal cations, in a concentration-dependent manner. Single nanofiber emission intensity was quite stable under continuous excitation permitting single fiber quenching-based metal ion detection whereby a significant (>90%) and prompt (sub-10 s) quenching was observed upon exposure to sub-millimolar Fe(iii) solutions. The introduction of these new 1D luminescent carbon nanofibers offers the potential for exciting developments across a range of applications.
Central venous catheters. Observations on the implantation technique and its complications. (2005)

The growing utilization of central venous catheterism is linked to the necessity of treating with an always larger number of hospitalized and nonhospitalized patients. The technological development provided us with different devices and materials for specific indications. In the majority of cases the central venous catheter is positioned through direct puncture of a central vein using Seldinger method. The vessels used for the catheterism are: the internal jugular vein, the subclavian vein and femoral vein. The choice of the vein to use is influenced by the operator's experience and by factors depending on the patient. The internal jugular vein via posterior or median and the subclavian vein via subclavicular are the most used sites in the central venous catheterism. However, also the femoral vein can be considered a resource when the clinical conditions of the patient render problematic the positioning in the above mentioned sites. The positioning into the internal jugular vein is generally burdened with a very low risk of pneumothorax and other potentially dangerous complications for the patient. The femoral vein is generally burdened with a larger incidence of thrombosis and infections. The subclavian vein, even if it is the most used, is burdened with a larger incidence of immediate or retarded pneumothorax and accidental venous puncture. The most frequent immediate complications for catheterism are the arterial puncture, pneumothorax, arrhythmias and the wrong positioning. Among the late complications there are the catheter infections correlated, catheter and vessel thrombosis. The use of a proper technique, completed by the operator's experience and the right management of the device, lead to a decrease of the risk level related to the central venous catheterism.
Expression, purification and crystallization of N-acetyl-(R)-β-phenylalanine acylases derived from Burkholderia sp. AJ110349 and Variovorax sp. AJ110348 and structure determination of the Burkholderia enzyme (2023)

N-Acetyl-(R)-β-phenylalanine acylase is an enzyme that hydrolyzes the amide bond of N-acetyl-(R)-β-phenylalanine to produce enantiopure (R)-β-phenylalanine. In previous studies, Burkholderia sp. AJ110349 and Variovorax sp. AJ110348 were isolated as (R)-enantiomer-specific N-acetyl-(R)-β-phenylalanine acylase-producing organisms and the properties of the native enzyme from Burkholderia sp. AJ110349 were characterized. In this study, structural analyses were carried out in order to investigate the structure-function relationships of the enzymes derived from both organisms. The recombinant N-acetyl-(R)-β-phenylalanine acylases were crystallized by the hanging-drop vapor-diffusion method under multiple crystallization solution conditions. The crystals of the Burkholderia enzyme belonged to space group P4<sub>1</sub>2<sub>1</sub>2, with unit-cell parameters a = b = 112.70-112.97, c = 341.50-343.32 Å, and were likely to contain two subunits in the asymmetric unit. The crystal structure was solved by the Se-SAD method, suggesting that two subunits in the asymmetric unit form a dimer. Each subunit was composed of three domains, and they showed structural similarity to the corresponding domains of the large subunit of N,N-dimethylformamidase from Paracoccus sp. strain DMF. The crystals of the Variovorax enzyme grew as twinned crystals and were not suitable for structure determination. Using size-exclusion chromatography with online static light-scattering analysis, the N-acetyl-(R)-β-phenylalanine acylases were clarified to be dimeric in solution.
Novel Insights into Wound Healing Sequence of Events (2007)

Effective wound healing leads to restoration of tissue integrity and occurs through a highly organized multistage process involving various cell types. Currently, methods for wound healing assessment lack a structured system for analysis of quantitative parameters. We have established a unique quantitative assessment strategy of wound healing stages based on histological criteria. Distinctive immunohistochemical parameters including re-epithelialization, epidermal differentiation, cell migration, proliferation, inflammatory response as well as dermal closure, matrix distribution, and skin remodelling were identified and followed during the timeline of wound healing progression. Assessment was based on various defined characteristics and each stage-specific parameter was independently quantified for complete wound closure. This analysis allowed a follow-up of wound healing dynamics and identified the contribution of critical and specific parameters to wound healing physiology and pathology. In this review we demonstrate our assessment strategy of crucial wound healing events and introduce a unique quantification system for each of the processes involved in wound repair. We believe that our unique method can be utilized as a diagnostic platform for standardizing assessment of wound healing progression as well as a screening tool for potential therapies.
Study of mother-to-child Epstein-Barr virus transmission by means of nested PCRs (1996)

The aim of this study was to investigate the possibility of vertical Epstein-Barr virus (EBV) transmission. We developed two nested-PCR methods for amplifying distinct regions of EBV DNA (BNRF1 and BamHI W) in circulating lymphocytes. Nested PCR was applied to samples obtained from 67 mother-infant pairs within 1 week of birth. We also tested samples from 16 neonates born to human immunodeficiency virus (HIV)-infected mothers to determine whether HIV increases the potential risk of vertical EBV transmission. About half of the 67 women in the first population were positive by nested PCR. Two neonates born to EBV PCR-positive women were also PCR positive. One of the 16 neonates born to HIV-infected women was PCR positive for EBV. These results strongly support the possibility of EBV transmission in utero or during delivery but do not suggest that HIV infection increases this risk. Further studies are required to confirm these findings, to identify the precise mode of vertical EBV transmission, and to determine the outcome for infants who are positive at birth for EBV DNA by nested PCR.
A multiwavelength fiber ring-laser employing a pair of silica-based arrayed-waveguide-gratings (1997)

A multiwavelength fiber ring-laser employing a pair of silica-based arrayed-waveguide-gratings (AWGs) is proposed to easily implement a stable multiwavelength operation for a variety of research needs. A fixed multiwavelength operation is available when the free-spectral-range (FSR) of the AWGs is wide enough to cover the gain bandwidth of deployed erbium-doped fiber amplifiers (EDFAs). A tunable multiwavelength operation is also available when the FSR is narrower than the gain bandwidth. 15 channels with 1.6-nm spacing in the fix type, and five channels with about 40-nm discretely tunable range at 1.4-nm spacing in the tunable type and almost 50-dB signal to amplified spontaneous emission (ASE) ratio in both types are demonstrated.
Effects of dopant induced defects on structural, multiferroic and optical properties of Bi1−xPbxFeO3(0 ≤x≤ 0.3) ceramics (2017)

Bi1−x Pb x FeO3 (0 ≤ x ≤ 0.3) has been characterized in detail with an aim to identify role of defect such as dopant, various vacancies, grain boundaries etc, and their effect on structural, optical and multiferroic properties. Structural analysis revealed that Pb substitution transforms the rhombohedral phase of BiFeO3 to the pseudocubic phase for x ≥ 0.15, consistently all vibrational Raman modes associated with the rhombohedral phase are found disappeared. Optical response revealed weakening of the d–d transitions with Pb addition indicating change in the Fe atoms environment consistent with the transition from non-centrosymmetric to the centrosymmetric structure. Transport and dielectric responses are explained in terms of hopping due to the presence of defects like oxygen vacancies and grain boundary conduction. In the high temperature regime, grain boundary conduction led to decrease in resistivity with the presence of a hump that is associated with hopping conduction. Extrinsic contributions in the transport properties correlate well with dielectric response. Magnetic and ferroelectric responses are also presented where role of oxygen vacancies defects has been clearly identified.
3-D-Printed High Data-Density Electromagnetic Encoders Based on Permittivity Contrast for Motion Control and Chipless-RFID (2020)

The 3-D-printed electromagnetic encoders based on permittivity contrast are presented and discussed in this article. The encoders, implemented using exclusively dielectric materials, are based on linear chains of dielectric inclusions. Two types of encoders are considered: 1) those where the inclusions are simple apertures made on a 3-D-printed dielectric plate (or substrate) and 2) those with inclusions made of high dielectric constant material 3-D-printed on a dielectric substrate (also 3-D-printed). In both cases, encoding is achieved by varying the dielectric constant of the substrate at predefined positions by means of the inclusions. For encoder reading, a microstrip line loaded with a slot resonator (etched in the ground plane) and a series gap is proposed. Such structure is very sensitive to short range dielectric constant variations, being able to detect the presence or absence of closely spaced inclusions when the encoder is displaced on top of the sensitive part of the reader, the slot resonator. For that purpose, the reader line is fed by a harmonic signal conveniently tuned, so that an amplitude-modulated (AM) signal containing the identification (ID) code is generated at the output port of the line. The proposed reader/encoder system is useful for motion control applications (linear displacement and velocity sensors) and for near-field chipless-radio frequency ID (RFID). Lower cost and major robustness against mechanical wearing are potential advantages of these encoders over other electromagnetic encoders based on a similar principle but based on metallic inclusions.
Incidence of Diabetes After Cancer Development (2018)

In this large Korean cohort, cancer development increased the risk of subsequent diabetes. These data provide evidence that cancer is associated with an increased risk of diabetes in cancer survivors independent of traditional diabetes risk factors. Physicians should remember that patients with cancer develop other clinical problems, such as diabetes, with higher frequency than individuals without cancer, and should consider routine diabetes screening in these patients.
Photoluminescent response of palladium-cadmium sulfide and palladium-graded cadmium sulfoselenide Schottky diodes to molecular hydrogen (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhotoluminescent response of palladium-cadmium sulfide and palladium-graded cadmium sulfoselenide Schottky diodes to molecular hydrogenMichael K. Carpenter, Hal Van Ryswyk, and Arthur B. EllisCite this: Langmuir 1985, 1, 5, 605–607Publication Date (Print):September 1, 1985Publication History Published online1 May 2002Published inissue 1 September 1985https://pubs.acs.org/doi/10.1021/la00065a016https://doi.org/10.1021/la00065a016research-articleACS PublicationsRequest reuse permissionsArticle Views74Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Regulation of Gene Expression Programs during Arabidopsis Seed Development: Roles of the ABI3 Locus and of Endogenous Abscisic Acid (1994)

, Christiane Valon, Monique Raynal, Pascale Gaubier-Comella, Michel Delseny, , Regulation of Gene Expression Programs during Arabidopsis Seed Development: Roles of the ABI3 Locus and of Endogenous Abscisic Acid, The Plant Cell, Vol. 6, No. 11 (Nov., 1994), pp. 1567-1582
Low-Rank Representation-Based Object Tracking Using Multitask Feature Learning with Joint Sparsity (2014)

We address object tracking problem as a multitask feature learning process based on low-rank representation of features with joint sparsity. We first select features with low-rank representation within a number of initial frames to obtain subspace basis. Next, the features represented by the low-rank and sparse property are learned using a modified joint sparsity-based multitask feature learning framework. Both the features and sparse errors are then optimally updated using a novel incremental alternating direction method. The low-rank minimization problem for learning multitask features can be achieved by a few sequences of efficient closed form update process. Since the proposed method attempts to perform the feature learning problem in both multitask and low-rank manner, it can not only reduce the dimension but also improve the tracking performance without drift. Experimental results demonstrate that the proposed method outperforms existing state-of-the-art tracking methods for tracking objects in challenging image sequences.