74 OCCUPATIONAL RISK FOR INITIAL BLADDER CANCER DIAGNOSIS IN BRAZIL (2012)

You have accessJournal of UrologyGeneral & Epidemiological Trends & Socioeconomics: Evidence-based Medicine & Outcomes II1 Apr 201274 OCCUPATIONAL RISK FOR INITIAL BLADDER CANCER DIAGNOSIS IN BRAZIL Sanarelly Adonias, Daher C. Chade, Alexandre C. Sant'Anna, Sabrina T. Reis, Daniel K. Abe, Flavio G.M. Areas, T.T. Suzaki, Katia R. Leite, Miguel Srougi, and Marcos F. Dall'Oglio Sanarelly AdoniasSanarelly Adonias Sao Paulo, Brazil More articles by this author , Daher C. ChadeDaher C. Chade Sao Paulo, Brazil More articles by this author , Alexandre C. Sant'AnnaAlexandre C. Sant'Anna Sao Paulo, Brazil More articles by this author , Sabrina T. ReisSabrina T. Reis Sao Paulo, Brazil More articles by this author , Daniel K. AbeDaniel K. Abe Sao Paulo, Brazil More articles by this author , Flavio G.M. AreasFlavio G.M. Areas Sao Paulo, Brazil More articles by this author , T.T. SuzakiT.T. Suzaki Sao Paulo, Brazil More articles by this author , Katia R. LeiteKatia R. Leite Sao Paulo, Brazil More articles by this author , Miguel SrougiMiguel Srougi Sao Paulo, Brazil More articles by this author , and Marcos F. Dall'OglioMarcos F. Dall'Oglio Sao Paulo, Brazil More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2012.02.120AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Although bladder cancer risk factors are well known, it is not clear what is the actual impact of daily occupation on current series. Smoking represents the main preventable risk variable, with almost 45% of cases associated. Occupational hazards is estimated to be related to bladder cancer development in 5% to 25% of patients, with wide variation of findings among different studies. We sought to analyze the impact of occupational risk, comparing patients with bladder cancer according to their professional activitiy and its association to symptoms, stage and oncologic outcomes. METHODS We included 100 patients with bladder cancer after transurethral resection between 2008 and 2011. 64% were male. We analyzed presenting symptoms, stage, grade, and number of lesions. A questionnaire regarding current and past profession, years of work and daily habits were applied in all patients. Patients included in group 1 were those with no professions previously related to bladder cancer risk. Group 2 represented patients at risk due to professions or activities that exposes workers to chemicals known as bladder carcinogens, such as in rubber and chemical industries. Statistical analysis was performed using chi-square and Fisher tests with SPSS v13. RESULTS Patients in group 2 presented significantly higher incidence of disuria as a presenting symptom (p=0.001). Patients in group 2 had a higher incidence of T1 disease at diagnosis (36% vs 18%), although not statistically significant (p=0.059). There was no difference among other variables between groups 1 and 2, such as rate of recurrence (21% vs 22%), 3 or more lesions (22% vs 19%), or grade. Also, other presenting symptoms (hematuria, urinary retention, frequency and urgency) had similar rates between the two groups. CONCLUSIONS Irritative urinary symptoms are more frequently encountered among patients with bladder cancer who are exposed to bladder carcinogens due to professional activities than with no occupational risks. Therefore, presenting symptoms may help in the initial bladder cancer diagnosis in patients with a history of occupational exposure. © 2012 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 187Issue 4SApril 2012Page: e31-e32 Advertisement Copyright & Permissions© 2012 by American Urological Association Education and Research, Inc.Metrics Author Information Sanarelly Adonias Sao Paulo, Brazil More articles by this author Daher C. Chade Sao Paulo, Brazil More articles by this author Alexandre C. Sant'Anna Sao Paulo, Brazil More articles by this author Sabrina T. Reis Sao Paulo, Brazil More articles by this author Daniel K. Abe Sao Paulo, Brazil More articles by this author Flavio G.M. Areas Sao Paulo, Brazil More articles by this author T.T. Suzaki Sao Paulo, Brazil More articles by this author Katia R. Leite Sao Paulo, Brazil More articles by this author Miguel Srougi Sao Paulo, Brazil More articles by this author Marcos F. Dall'Oglio Sao Paulo, Brazil More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...