gebhart/patrepeval huggingface dataset:
New estimates for solutions of Lyapunov equations (1993)

The estimation problem for the solution of the Riccati and Lyapunov matrix equations has attracted considerable attention in the past two decades. In most works, the lower and upper bounds for the following quantities of the solution of the Riccati and Lyapunov matrix equations are obtained: the smallest eigenvalue the largest eigenvalue, the trace, the determinant, the partial summation of eigenvalues, the partial product of eigenvalues, the solution itself. Komaroff (1990, 1988, 1992) used majorisation techniques to obtain some very excellent estimates for the partial summation and partial product of the solution of Lyapunov matrix equations. Mrabti and Hmamed (1992) presented a unified approach using the delta operator technique to obtain lower bound estimates for the solution of both the continuous-time and discrete-time Lyapunov matrix equations. A common assumption for most of results is that A+A' is negative definite, i.e., /spl lambda//sub 1/(A+A') < O. This is obviously restrictive, because the stability of A does not guarantee this assumption. In this paper, the authors remove this assumption and give some more general estimates for the continuous-time Lyapunov matrix differential and algebraic equations.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Cross‐Coupling Reactions on Azoles with Two and More Heteroatoms (2006)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Nonuniform transverse distribution of the light intensity and polarisation upon sum-frequency generation from the surface of an isotropic gyrotropic medium in the case of normal incidence of light (2009)

Sum-frequency generation from the surface of an isotropic gyrotropic medium by two normally incident homogeneously elliptically polarised Gaussian beams is studied theoretically. Analytic expressions, completely describing the transverse spatial distribution of the intensity and polarisation in the cross section of the reflected beam at the sum frequency, were derived taking into account both the local and nonlocal contributions of the quadratic nonlinearity of the medium thicknesses and the nonlinear contribution of its surface. It is shown that a special selection of the parameters of the fundamental waves allows one to determine components of the surface susceptibility tensor.
Suppression of Tumor Necrosis Factor-mediated Apoptosis by Nuclear Factor κB-independent Bone Morphogenetic Protein/Smad Signaling (2001)

The activation of nuclear factor kappaB (NF-kappa B) plays a pivotal role in the regulation of tumor necrosis factor (TNF)-mediated apoptosis. However, little is known about the regulation of TNF-mediated apoptosis by other signaling pathways or growth factors. Here, unexpectedly, we found that bone morphogenetic protein (BMP)-2 and BMP-4 inhibited TNF-mediated apoptosis by inhibition of caspase-8 activation in C2C12 cells, a pluripotent mesenchymal cell line that has the potential to differentiate into osteoblasts depending on BMP stimulation. Utilizing both a trans-dominant IkappaBalpha inhibitor of NF-kappaB expressed in C2C12 cells and IkappaB kinase beta-deficient embryonic mouse fibroblast, we show that BMP-mediated survival was independent of NF-kappaB activation. Rather, the antiapoptotic activity of BMPs functioned through the Smad signaling pathway. Thus, these findings provide the first report of a BMP/Smad signaling pathway that can inhibit TNF-mediated apoptosis, independent of the prosurvival activity of NF-kappaB. Our results suggest that BMPs not only stimulate osteoblast differentiation but can also promote cell survival during the induction of bone formation, offering new insight into the biological functions of BMPs.
Using Correlation Functions as Free Decays (2018)

It is a general assumption in OMA that correlation functions are free decays. In multiple input OMA this assumption also implies that any column in the correlation function matrix is to be considered as multiple output free decays. This assumption is discussed in this paper together with issues concerning estimation and application of correlations functions in OMA.
Immobilizing hydrolytic active Papain on biodegradable PLLA for biofilm inhibition in cardiovascular applications (2020)

Abstract The use of biomaterials in medicine is becoming increasingly important. One of the main concerns is the foreign body associated infection caused by direct microbial contamination or clinical infections. The bacterial biofilm formation on biomaterials depends on their surface properties. Therefore, several anti-adhesive surface modifications were developed. Nevertheless, the demand for antimicrobial agents that prevent bacterial colonisation is still largely unmet. The immobilization of active antimicrobial agents, such as antibacterial peptides or enzymes, offers a potential approach to achieve long-lasting effectiveness. In this investigation, the hydrolytic enzyme papain with its published antibacterial activity was covalently immobilized on the well-established biodegradable biomaterial poly-L-lactic acid (PLLA). For the characterization of the enzymes on the PLLA surfaces, the protein content and enzyme activity were determined. A biofilm assay was performed to test the effect of the papain-modified PLLA samples on the biofilm-forming bacterial strain Clostridioides difficile, one of the most frequently occurring human nosocomial pathogens. The investigated hydrolytic enzyme papain could be immobilized by coupling via the crosslinker EDC to the PLLA surface. Detection was performed by determination of the amount of protein and the reduced biofilm growth after 24 h and 72 h compared to the reference.
The Bush Burned With Fire And The Bush Was Not Consumed (2019)

Skin draws gaunt to his skull, deflating jowls he has borne across eight decades.
A novel algorithm for refinement of vision-based two-view pose estimates (2009)

A novel method is developed to obtain a refined estimate of relative position and orientation (pose) from two views captured by a calibrated monocular camera. Due to the typically large number of matched pairs of feature points available, many estimates of the pose are possible by taking minimal sets of feature points. Among such estimates, the proposed method selects a subset that has low estimation error, and averages them in an appropriate manner to provide a refined estimate. Preliminary experiments on the image data show that the proposed method provides a more accurate pose estimate than refinement using a least squares method.
Whisker Growth induced by Ag photodoping in glassy GexSe1−x films (1980)

The growth and disappearance of crystalline Se whiskers in glassy GexSe1−x films ( with x=0.1 and (1)/(3) ) during the process of Ag photodoping have been studied by electron microscopy. The longitudinal growth direction of the whiskers is found to be parallel to the c axis of the Se hexagonal lattice.
[Dwarf colony mutants of "Escherichia coli" study of a strain isolated from an uroculture (author's transl)]. (1977)

A dwarf colony mutant of Escherichia coli was isolated from the urine of a patient with an asymptomatic urinary infection. This dwarf mutant growths poorly (minute transparent colonies) on Trypticase Soja and Mueller-Hinton agar, and requires thiamine concentration of 3 x 10-11 M.
Possible Regulation of the Conventional Calpain System by Skeletal Muscle-specific Calpain, p94/Calpain 3 (2004)

p94 (also called calpain 3) is the skeletal muscle-specific calpain and is considered to be a "modulator protease" in various cellular processes. Analysis of p94 at the protein level is an urgent issue because the loss of p94 protease activity causes limb-girdle muscular dystrophy type 2A. In this study, we enzymatically characterized one alternatively spliced variant of p94, p94:exons 6(-)15(-)16(-) (p94delta), which lacks two of the p94-specific insertion sequences. In contrast to p94, which has hardly been studied enzymatically due to its rapid, thorough, and apparently Ca(2+)-independent autolytic activity, p94delta was stably expressed in COS and insect cells. p94delta showed Ca(2+)-dependent caseinolytic and autolytic activities and an inhibitor spectrum similar to those of the conventional calpains. However, calpastatin did not inhibit p94delta and is a substrate for p94delta, which is consistent with the properties of p94, presenting p94 as a possible regulator of the conventional calpain system. We also established a semi-quantitative fluorescence resonance energy transfer assay using the calpastatin sequence specifically to measure p94 activity. This method detects the activity of COS-expressed p94 and p94delta, suggesting that it has potential to evaluate p94 activity in vivo and in the diagnosis of limb-girdle muscular dystrophy type 2A.
Recurrent involvement of 2p23 in inflammatory myofibroblastic tumors. (1999)

Inflammatory myofibroblastic tumor (IMT) is a relatively rare soft tissue tumor. The reactive versus neoplastic pathogenesis of this tumor is unresolved. We found clonal chromosome aberrations involving 2p23 upon metaphase analysis of two IMTs. Fluorescence in situ hybridization with a probe flanking the ALK gene at 2p23 demonstrated rearrangement of the probe in both of these cases and in a third case, and immunohistochemistry revealed ALK expression in all three cases. 2p22-24 involvement has been reported previously in four additional cases of IMT. We suggest that chromosomal rearrangements involving 2p23 near or within ALK are recurrent alterations in IMT and that ALK may have a novel role outside its previously recognized realm of lymphoid neoplasms.
Dermoscopy Findings of Hidroacanthoma Simplex (2014)

Hidroacanthoma simplex (HAS), also known as intraepidermal eccrine poroma, is a rare eccrine adnexal tumor that tends to be misdiagnosed as other types of benign skin tumor, including clonal seborrheic keratosis. Notably, HAS is sometimes misdiagnosed and treated by cryosurgery as seborrheic keratosis, which could trigger the later development of porocarcinoma. Therefore, accurate diagnosis of HAS is indispensable for dermatologists to avoid the development of malignant tumors by an unsuitable treatment. In this report, we present the characteristic dermoscopy findings of HAS. Indeed, the dermoscopy findings might be related to the melanin-rich necrotic cells in the epidermis, which are quite different from dermoscopy findings of clonal seborrheic keratosis. As a previous report suggested, it is difficult for a dermatologist to differentiate HAS from clonal seborrheic keratosis by the naked eye. Our findings might be supportive for the early diagnosis of HAS.
Efficient storage and processing of large guided wave data sets with random projections (2020)

Over the last several decades, structural health monitoring systems have grown into increasingly diverse applications. Structural health monitoring excels with large data sets that can capture the typical variability, novel events, and undesired degradation over time. As a result, the efficient storage and processing of these large, guided wave data sets have become a key feature for successful application of structural health monitoring. This article describes a series of investigations into the use of random projection theory to significantly reduce storage burdens and improve computational complexity while not significantly affecting common damage detection strategies. Random projections are used as a lossy compression scheme that approximately retains metrics of distance or similarity between data records. Random projection compression is evaluated using a large 1,440,000 measurement data set, which was collected over 5 months in an unprotected outdoor environment. Accurate damage detection, after the compression process, is achieved through correlation analysis and singular value decomposition. The results indicate consistent detection performance with over 95% of storage compression and more than a 477 times speed improvement in computational cost for singular value decomposition–based damage detection.
Effects of Herbicides and Application Timing on Woollyleaf Bursage(Ambrosia grayi)1 (2000)

Woollyleaf bursage (Ambrosia grayi) is a noxious, rhizomatous perennial with an extensive creeping root system. It is found in the central and southern Great Plains of the U.S. Clopyralid alone or fluroxypyr, picloram, or glyphosate with either 2,4-D or dicamba were applied to woollyleaf bursage at anthesis and 30 d later in three field experiments. With the exception of treatments containing picloram, the effect of application timing was inconsistent. All treatments containing picloram consistently controlled woollyleaf bursage 93% or greater for 9 mo and 74% or greater for 11 mo. Control was poor or inconsistent with all other treatments. Although a rate response was seen with clopyralid, a level higher than 0.28 kg/ha may be necessary to control woollyleaf bursage. After 11 mo, control was less than 60% with treatments containing 1.7 kg/ha of glyphosate in 10 of 12 herbicide treatments and timing combinations over 3 yr.Nomenclature: Clopyralid, 3,6-dichloro-2-pyridinecarboxylic acid; dicamba, 3,6-dichloro-2-methoxybenzoic acid; fluroxypyr, [(4-amino-3,5-dichloro-6-fluoro-2-pyridinyl)oxy]acetic acid; glyphosate, N-(phosphonomethyl)glycine; picloram, 4-amino-3,5,6-trichloro-2-pyridinecarboxylic acid; 2,4-D, (2,4-dichlorophenoxy)acetic acid; woollyleaf bursage, Ambrosia grayi (A. Nels.) shinners #3AMBGR.Additional index words: Woollyleaf franseria, bur ragweed, perennial weed control.
Über Spiroverbindungen des Isochromans (II. Mitteil. Über Isochroman) (1956)

Abstract Aus l‐Alkyl‐isochromanen entstehen durch Bromierung und anschließende Verseifung alkalilösliche Verbindungen, die sich bei Einwirkung von Säuren durch dreifachen Ringschluß zu Dispirodiisochroman‐1.4‐dioxanen kondensieren. Aus l‐Methyl‐ isochromanyl‐(1)‐hydroperoxyd und Benzaldehyd entsteht in stark alkalischem Medium durch eine neuartige Peroxydumlagerung ein Spiroisochroman‐1.3‐dioxolan.
Dynamic Complexity of the Microglial Activation Response in Transgenic Models of Amyloid Deposition: Implications for Alzheimer Therapeutics (2005)

The presence of activated microglia in postmortem Alzheimer disease specimens is used to support the argument that inflammation contributes to Alzheimer pathogenesis. Transgenic mice overexpressing the amyloid precursor protein (APP) gene form amyloid plaques that are accompanied by local activation of microglia/macrophages in a manner similar to the human disease. Many markers of microglial activation and inflammation increase in an age-dependent manner in these mice. However, manipulation of these inflammatory reactions can lead to unexpected outcomes with several instances of reduced pathology when microglia/macrophages are activated further. In particular, anti-Abeta immunotherapy in amyloid-depositing transgenic mice causes a complex series of changes in microglial markers, negating the implicit belief that such activation is monotonic and represented equally well by any of several "activation" markers. A survey of the peripheral macrophage literature identifies at least 2 distinct activation states of macrophages with different consequences for the surrounding tissue. These different activation states can often be distinguished by the markers that are expressed. Several markers are identified from studies outside the brain that neuroscientists might consider evaluating when attempting to more definitively describe the activation state of the monocyte-derived cells in the brain.
Credit-Based Authorization for Binding Lifetime Extension (2004)

Mobile IPv6 return routability mechanisms require home and care-of address keygen tokens to be used to authorize a binding update to correspondent nodes. The current rules dictate that such authorization be performed every seven minutes, using tokens at most three and half minutes old. This requirement results in an average signaling traffic of around 7 bits per second when the hosts are not moving around. This traffic load by itself is neglible, but can be problematic for hosts in standby mode. We present a secure and lightweight extension of return routability that can reduce this signaling load to around 0.1 bits per second, and require hosts to wake up much less frequently.
Effect of glucose and ascorbic acid on total phenolic content estimation of green tea and commercial fruit juices by using Folin Ciocalteu and Fast Blue BB assays (2019)

Folin Ciocalteu (FC) assay had been widely used in the estimation of total phenolics content (TPC) in foods. However, the main disadvantage of this assay is that the reagent reacts with reducing substances and measures the total reducing capacity of a sample, not just phenolic compounds. The Fast Blue BB (FBBB) assay is another assay that can be used to estimate the total phenolic content in foods instead. The aim of the study was to estimate and compare the total phenolic content of green tea and commercial fruit juices using FC and FBBB assays, and also the effects of glucose and ascorbic acid on both assays. Green tea had the highest ascorbic acid content and TPC value among the samples. TPC estimated using FC assay were significantly higher than FBBB assay in all the samples. FC and FBBB assays were not affected by glucose at different concentrations. However, FC assay was significantly affected by the presence of ascorbic acid compared to FBBB assay. In conclusion, FC assay overestimated the TPC value in the sample extracts and was significantly affected by the presence of ascorbic acid. The FBBB assay can be considered as an alternative for estimation of total phenolic content in ascorbic acid-rich foods.
Antioxidant Activity of Uva di Troia Canosina: Comparison of Two Extraction Methods (2015)

Two extraction methods: microwave-assisted extraction (MAE) and extraction by convection heating were used to assess the active antioxidant ingredients from Uva di Troia Canosina grape pomace. MAE gave higher yields in the recovery of resveratrol (70 µg/g versus 20 µg/g) as assessed by capillary electrophoresis (CE) analysis. The MAE was also advantageous as it allowed reduced extraction times: 15 minutes versus 30 minutes required by conventional heating extraction. However, both methods gave extracts endowed with comparable antioxidant activity as demonstrated by the 2,2-diphenyl-1- picrylhydrazyl radical (DPPH) scavenging assay (IC50 = 106±48 µg/mL versus 110±34 µg/mL, respectively). The observed antioxidant effect of the MAE extract appears to be correlated with the detected resveratrol concentration while other unidentified antioxidants may contribute to the radical scavenging effect of the extract obtained by convection heating. In agreement with previous results, our study underlays the possibility that the antioxidant properties of Uva di Troia Canosina grape could be attributed to resveratrol along with other polyphenols. Considering the multifunctional medicinal and health effects of resveratrol, the MAE method herein proposed may be considered as an efficient way to obtain resveratrol from Uva di Troia Canosina grapes. Keywords: Capillary electrophoresis, DPPH, environment, microwave, polyphenols, resveratrol, Uva di Troia.
ChemInform Abstract: Stereoselective Aldol Addition of a Chiral Glycine Enolate Synthon to Heteroaromatic Aldehydes. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
The Role of Patient Activation in Improving Blood Pressure Outcomes in Black Patients Receiving Home Care (2013)

Variations in patients' self-management knowledge, skills, and confidence as measured by the Patient Activation Measure (PAM) have been linked to variations in health behavior and outcomes. In a randomized trial, we tested two blood pressure (BP) control interventions, one grounded in activation principles. Study participants were Black home care patients (N = 587) with uncontrolled hypertension. This article examines intervention impacts on 12-month PAM score change, other predictors of PAM change, and associations between PAM change and BP outcomes. In multivariate models, the interventions did not significantly affect PAM change. Baseline characteristics associated with increased PAM were lower PAM score, higher income, higher health literacy, younger age, lower systolic BP, diabetes, and fewer medications. PAM increase was associated with a modest reduction in diastolic BP but not with improved systolic BP or BP control. Although studies suggest that increasing activation may lead to improved patient outcomes, this study did not find it to be so.
FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer (2007)

FGFR3 is frequently activated by mutation in urothelial carcinoma (UC) and represents a potential target for therapy. In multiple myeloma, both over-expression and mutation of FGFR3 contribute to tumour development. To define the population of UC patients who may benefit from FGFR-targeted therapy, we assessed both mutation and receptor over-expression in primary UCs from a population of new patients. Manual or laser capture microdissection was used to isolate pure tumour cell populations. Where present, non-invasive and invasive components in the same section were microdissected. A screen of the region of the highest tumour stage in each sample yielded a mutation frequency of 42%. Mutations comprised 61 single and five double mutations, all in hotspot codons previously identified in UC. There was a significant association of mutation with low tumour grade and stage. Subsequently, non-invasive areas from the 43 tumours with both non-invasive and invasive components were analysed separately; 18 of these had mutation in at least one region, including nine with mutation in all regions examined, eight with mutation in only the non-invasive component and one with different mutations in different regions. Of the eight with mutation in only the non-invasive component, six were predicted to represent a single tumour and two showed morphological dissimilarity of fragments within the block, indicating the possible presence of distinct tumour clones. Immunohistochemistry showed over-expression of FGFR3 protein in many tumours compared to normal bladder and ureteric controls. Increased expression was associated with mutation (85% of mutant tumours showed high-level expression). Overall, 42% of tumours with no detectable mutation showed over-expression, including many muscle-invasive tumours. This may represent a non-mutant subset of tumours in which FGFR3 signalling contributes to the transformed phenotype and which may benefit from FGFR-targeted therapies.