gebhart/patrepeval huggingface dataset:
An in-depth study of long-term users of transcutaneous electrical nerve stimulation (TENS). Implications for clinical use of TENS (1991)

This in-depth study examines the relationships between patient, stimulator and outcome variables in a large number of chronic pain patients utilising TENS on a long-term basis. 179 patients completed a TENS questionnaire designed to record age, sex, cause and site of pain and TENS treatment regime. Of these 179 patients, 107 attended our research unit for assessment of the electrical characteristics of TENS during self-administered treatment. Although a remarkable lack of correlation between patient, stimulator and outcome variables was found to exist, the analysis revealed much information of importance: 47% of patients found TENS reduced their pain by more than half; TENS analgesia was rapid both in onset (less than 0.5 h in 75% patients) and in offset (less than 0.5 h in 51% patients); one-third of patients utilised TENS for over 61 h/week; pulse frequencies between 1 and 70 Hz were utilised by 75% of patients; 44% of patients benefitted from burst mode stimulation. The clinical implications of these findings are discussed.
Preliminary evaluation of the impact of preharvest UV-C on lettuce: potential for the control of Xanthomonas campestris (2020)

ISHS XXX International Horticultural Congress IHC2018: III International Symposium on Innovation and New Technologies in Protected Cultivation Preliminary evaluation of the impact of preharvest UV-C on lettuce: potential for the control of Xanthomonas campestris
Central Arterial Compliance Is Associated With Age- and Habitual Exercise–Related Differences in Cardiovagal Baroreflex Sensitivity (2001)

Background- Cardiovagal baroreflex sensitivity (BRS) declines with age but is favorably modulated by habitual aerobic exercise. We tested the hypothesis that compliance (transducing capacity) of an elastic artery in which baroreceptors are located is associated with these age-exercise interactions. Methods and Results- Nine young (28+/-1 years old) and 9 older (65+/-1) sedentary and 10 young (27+/-1) and 9 older (63+/-2) endurance-trained healthy men were studied. Cardiovagal BRS was assessed conventionally (R-R interval-systolic blood pressure [SBP] relation) by the Oxford technique. Because of age-associated increases in central arterial stiffness, cardiovagal BRS was expressed with both peripheral (Finapres) and central (applanation tonometry) SBP values. The change in carotid artery end-systolic lumen diameter (ultrasonography) per unit increase in SBP and the slope of the R-R interval-carotid artery diameter relation also were determined. Cardiovagal BRS declined with age in both sedentary ( approximately 65%) and endurance-trained ( approximately 40%) men but was higher in endurance-trained than sedentary older men regardless of the SBP values used (all P<0.05). Changes in carotid artery lumen diameter per unit increase in SBP mirrored these differences in cardiovagal BRS (all P<0.05). Thus, R-R interval prolongation per unit increase in carotid artery diameter was not different among the groups (P>0.70). Conclusions- These results demonstrate that age- and habitual exercise-related differences in cardiovagal BRS are associated with corresponding differences in carotid artery compliance among healthy men.
Low ileal interleukin 10 concentrations are predictive of endoscopic recurrence in patients with Crohn's disease (2002)

Low ileal IL-10 mRNA concentration is a good marker of endoscopic recurrence in Crohn's disease but the distribution of IL-10.G haplotypes cannot predict the postoperative evolution of the disease.
Formosan Subterranean Termite (Isoptera: Rhinotermitidae) Soldiers Regulate Juvenile Hormone Levels and Caste Differentiation in Workers (2005)

A caste structure is maintained in termite societies and juvenile hormone (JH) is generally regarded as the most important regulator in these termite colonies. Here, we demonstrate that the soldier caste regulates JH in workers of Coptotermes formosanus Shiraki. Worker termites (80–100 individuals) were placed in petri dishes with 0, 5, 10, or 20% soldiers. JH III titers of groups of these workers were monitored at 14, 28, 42, and 56 d. Any changes in soldier caste proportions also were noted at each sample date. On the first sample date, the JH levels in workers were similar among treatments with different initial soldier proportions, and no new soldiers were formed. Over the next three sample dates, the worker JH levels were higher for low initial soldier proportion treatments and vice versa. Concurrently, soldier formation increased with lower initial soldier proportions. JH titers in workers showed a positive and statistically significant relationship to soldier numbers until a certain soldier proportion was reached. These results provide evidence that soldier caste proportions regulate JH levels and thereby caste differentiation in workers. The means by which this regulatory mechanism may proceed is discussed.
THE EFFECTS OF THREE PSO GENES ON INDUCED MUTAGENESIS: A NOVEL CLASS OF MUTATIONALLY DEFECTIVE YEAST (1980)

Reverse and forward mutation, induced by photoaddition of 8-methoxypsoralen (8-MOP) and 3-carbethoxypsoralen (3-CPs) or ultraviolet light (UV), are reduced in three pso mutants of Saccharomyces cerevisiae. The pso1-1 strain exhibits a lower frequency of spontaneous reversion (anti-mutator) and is almost entirely unaffected by the three agents in both the haploid and diploid states. The pso2-1 strain demonstrates very reduced frequencies of 8-MOP and 3-CPs plus 365 nm radiation-induced mutations in haploid and diploid cells. UV-induced mutation are slightly reduced, whereas survival is almost normal. The pso3-1 strain is mutable by 8-MOP and 3-CPs photoaddition only in the low-dose range. After UV treatment, survival of pso3-1 is nearly normal, whereas the frequencies of induced mutants are diminished as compared to the normal PSO+. An analogue of adenine, 6-N-hydroxyaminopurine, is capable of inducing reversions in wild type, as well as in pso and rad6-1 mutant strains, indicating that this drug may act as a direct mutagen in yeast. The comparison of photoaddition of the bifunctional agent (8-MOP) to that of the monofunctional one (3-CPs) confirms that cross-links, as well as monoadditions, are mutagenic in S. cerevisiae. Repair, of the recombinational type, taking place in diploid cells or in haploid cells in G2 phase leads to higher survival, but appears to be error-free.
Synthesis and Magnetic and Structural Characterization of the First Homoleptic Lanthanide β-Ketoiminate. (2001)

Synthesis and Magnetic and Structural Characterization of the First Homoleptic Lanthanide &lt;i&gt;β&lt;/i&gt;-Ketoiminate
Linear Response Function for Fluorescence-Based Fiber-Optic CO2 Sensors (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLinear Response Function for Fluorescence-Based Fiber-Optic CO2 SensorsXiaoying. He and Garry A. RechnitzCite this: Anal. Chem. 1995, 67, 13, 2264–2268Publication Date (Print):July 1, 1995Publication History Published online1 May 2002Published inissue 1 July 1995https://pubs.acs.org/doi/10.1021/ac00109a054https://doi.org/10.1021/ac00109a054research-articleACS PublicationsRequest reuse permissionsArticle Views238Altmetric-Citations26LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A novel soft error mitigation approach for SRAM-based FPGAs (2012)

SRAM-based FPGA devices are susceptible to Single Event Effects (SEE) inside configuration memory. Most approaches for soft error mitigation use Triple Modular Redundancy (TMR) to avoid the consequences of these errors. The drawback is that TMR implementation results in a triplication of required hardware and therefore TMR increases the power consumption. This paper describes a novel approach of soft error mitigation technique for SRAM-based Field Programmable Gate Arrays without using the Triple Modular Redundancy approach. Based on additional logic storing the correct states, it is capable of detecting Single Event Upsets (SEUs), reconfiguring the system and to correct the detected errors via rollback to the last known correct state. The approach was implemented as a prototype and this paper describes the first results of our research and shows that it is possible to mitigate soft errors in a efficient way but not with the same safety level TMR does.
Room temperature terahertz detection based on plasma resonance of electrons in an Antenna-Coupled GaAs MESFET (2008)

Plasma resonance of electrons is observed in an Antenna-Coupled Metal-Semiconductor-Field-Effect-Transistor (MESFET) by sweeping bias voltages. This resonant absorption is exploited to realize a room temperature terahertz detector with a measured Noise Equivalent Power (NEP) ∼ 5×10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">−8</sup> W/Hz <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">½</sup> .
Dynamic Constitution of the Pathogens Inducing Encephalitis in Hand, Foot and Mouth Disease in Kunming, 2009&ndash;2011 (2015)

Hand, foot and mouth disease (HFMD), caused by various viral pathogens, is an emerging infectious disease in children in Asia. Understanding the composition of these pathogens is necessary to prevent and control this disease. In the present study, the pathogens in 436 HFMD patients (from 2009 to 2011) with concurrent clinical indications of encephalitis, meningoencephalitis, or both, were defined using the semi-nested PCR. A systematic analysis of the composition of these pathogens was performed. Various enteroviruses that are capable of inducing central nervous system (CNS) damage in HFMD patients were identified, including enterovirus 71, coxsackievirus A16, and Echovirus 9. Most of these pathogens were found co-infecting the patients. The composition of the pathogens that induced CNS damage in the HFMD patients was dynamically modulated in the cases.
Solid phase epitaxial recrystallization of thin polysilicon films amorphized by silicon ion implantation (1982)

Thin polycrystalline silicon films have been amorphized by silicon ion implantation and subsequently annealed at 525 °C for various lengths of time. Due to channeling of the ion beam through properly oriented polycrystalline grains, a few grains survived the implantation step and acted as seeds for solid phase epitaxial recrystallization of the film. This technique makes it possible to increase the grain size of thin polycrystalline films at very low temperatures.
Role of arginine, taurine 4 and homocysteine in cardiovascular diseases (1999)

Arginine, taurine and homocysteine are amino acids which have been shown to affect the risk factors of cardiovascular diseases in humans. Arginine and taurine may protect against cardiovascular diseases while homocysteine may be a risk factor for them. Both arginine and taurine seem to lower blood pressure, arginine may also inhibit atherogenesis, and taurine may have antioxidant properties. However, the evidence of the beneficial effects of arginine and taurine supplementation from human studies is insufficient. Elevated levels of plasma homocysteine may be associated with atherosclerotic and thromboembolic cardiovascular diseases. Supplementation with folic acid seems to be effective in reducing hyperhomocysteinaemia, but there is an insufficient number of studies showing that lowering of homocysteine levels with vitamin supplementation will reduce the risk of cardiovascular diseases. In conclusion, further research is needed to determine the optimal levels for taurine and arginine in the human diet in order to decrease the risk factors for cardiovascular diseases, and to whom supplementation with folic acid should possibly be recommended to reduce hyperhomocysteinaemia. Even though the use of arginine and taurine supplements to reduce cardiovascular risk factors is an interesting possibility, the reported health-promoting effects and the safety of such a supplementation should first be confirmed.
Improved air gap permeance model to characterise the transient behaviour of electrical machines using magnetic equivalent circuit method (2020)

Abstract Transient analysis of electrical machines with mixed eccentricity requires dedicated, fast and accurate solvers. This article proposes an improved air gap permeance expression which (a) is physically interpretable and (b) can be easily derived based on the rotor position. This expression is very suitable for inclusion in a solver based on the magnetic equivalent circuit (MEC) method. This allows to for example, calculate the torque and forces when vibrations act on the rotor. The results of the MEC solver agree very well with those obtained with a finite element method (FEM) solver, but are obtained with a fraction of the simulation time of the FEM solver.
Patients With Preoperative Cervical Deformity Experience Similar Clinical Outcomes to Those Without Deformity Following 1–3 Level Anterior Cervical Decompression and Fusion (2021)

III.
Insight into cold- and melt crystallization phenomena of a smectogenic liquid crystal (2022)

This paper describes the insight into the different nature of cold- and melt crystallization kinetics of a smectogenic liquid crystal.
Representing Diversity in the Dish: Using Patient-Derived in Vitro Models to Recreate the Heterogeneity of Neurological Disease (2018)

Neurological diseases, including dementias such as Alzheimer's disease (AD) and fronto-temporal dementia (FTD) and degenerative motor neuron diseases such as amyotrophic lateral sclerosis (ALS), are responsible for an increasing fraction of worldwide fatalities. Researching these heterogeneous diseases requires models that endogenously express the full array of genetic and epigenetic factors which may influence disease development in both familial and sporadic patients. Here, we discuss the two primary methods of developing patient-derived neurons and glia to model neurodegenerative disease: reprogramming somatic cells into induced pluripotent stem cells (iPSCs), which are differentiated into neurons or glial cells, or directly converting (DC) somatic cells into neurons (iNeurons) or glial cells. Distinct differentiation techniques for both models result in a variety of neuronal and glial cell types, which have been successful in displaying unique hallmarks of a variety of neurological diseases. Yield, length of differentiation, ease of genetic manipulation, expression of cell-specific markers, and recapitulation of disease pathogenesis are presented as determining factors in how these methods may be used separately or together to ascertain mechanisms of disease and identify therapeutics for distinct patient populations or for specific individuals in personalized medicine projects.
Viral Vaccine Production in Cell Culture (2000)

Mechanics of Viral Vaccine Production Viral Seeds Cell Banks Cultivation Purification Inactivation Finishing Host Cell Substrate and Cell Growth Primary Cells Human Diploid Cells Continuous Cells Recombinant Cells Cell Growth Considerations Viral Growth Transport Attachment Viral Penetration and Uncoating Replication of Viral Components Assembly of Viral Components Viral Processing Growth Kinetics and Process Configuration Viral Assay Considerations Vaccines and Examples of Processes Poliovirus Vaccines Measles and Mumps Viral Vaccines Rubella Viral Vaccines Rabies Virus Foot-and-Mouth Disease Virus Vaccines Other Vaccines Future Vaccine Processes New Approaches to Old Vaccines New Vaccines Conclusions Further Reading Acknowledgments Bibliography
The Complex Biology of FOXO (2011)

FOXO transcription factors control proliferation, apoptosis, differentiation and metabolic processes. Loss of FOXO function has been identified in several human cancers, and results in increased cellular survival and a predisposition to neoplasia, especially in epithelial cancer. FOXO factors are therefore bona fide tumor suppressors, and their potential use as therapeutic targets in cancer has been a matter of debate. Importantly, FOXO factors can also positively regulate cell survival through the activation of several detoxification genes, complicating its putative therapeutic potential. Targeting of FOXO factors has also been proposed for the treatment of metabolic dysfunctions such as diabetes mellitus, immunological disorders and neurodegeneration, as well as for the prevention of aging by maintaining the hematopoyetic stem cells niche. But again, data has accumulated that cautions against the potential use of the FOXO activators in these settings. Therefore, greater understanding of the regulation of FOXO target specificity is still needed to boost its use as a therapeutic target. The four members of the FOXO family (FOXO1, FOXO3A, FOXO4 and FOXO6) have distinct but overlapping cellular functions, although they seem to bind a common set of DNA sites. This fact together with the observation that FOXOs are only partially dependent on their DNA binding activity to regulate their target genes highlights the fact that the interaction of the FOXOs with other transcription factors is crucial for the FOXO-mediated transcriptional programs. In this review, we provide an overview of recent progress in the understanding of the modulation of FOXO activity and target specificity by transcription factors and coactivators.
Transient rotation of photospheric vector magnetic fields associated with a solar flare (2017)

As one of the most violent eruptions on the Sun, flares are believed to be powered by magnetic reconnection. The fundamental physics involving the release, transfer, and deposition of energy have been studied extensively. Taking advantage of the unprecedented resolution provided by the 1.6 m Goode Solar Telescope, here, we show a sudden rotation of vector magnetic fields, about 12-20° counterclockwise, associated with a flare. Unlike the permanent changes reported previously, the azimuth-angle change is transient and cospatial/temporal with Hα emission. The measured azimuth angle becomes closer to that in potential fields suggesting untwist of flare loops. The magnetograms were obtained in the near infrared at 1.56 μm, which is minimally affected by flare emission and no intensity profile change was detected. We believe that these transient changes are real and discuss the possible explanations in which the high-energy electron beams or Alfve'n waves play a crucial role.
Electrospun fibrous mats as a skeleton for fabricating hierarchically structured materials as sorbents for Cu2+ (2012)

Based on the combination of the electrospinning and evaporation-induced self-assembly mesopore-forming technique, a facile strategy is developed to fabricate self-standing thiol-functionalized membranes with hierarchical structures (Macro-Mesopores and binding sites). This membrane is prepared using electrospun polystyrene (PS) fibers as the skeleton and non-ionic surfactant F127 as the structure-directing agent with co-condensation of tetraethyl orthosilicate (TEOS) and 3-mercaptopropyltrimethoxysilane (MPTMS). The prepared membranes were characterized by X-ray diffraction (XRD), transmission electron microscope (TEM), scanning electron microscope (SEM), nitrogen sorption, mercury intrusion porosimetry, and Fourier transform infrared (FT-IR) spectra. The macropore constructed by the electrospun PS membrane ranged from 1 to 10 μm, while the highly ordered mesopore formed by F127 was around 5 nm and heavy metals binding cites of thiol groups were also presented, respectively. Using Cu2+ ions as the model bivalent cation, an excellent removal capacity of the prepared membrane was confirmed by the static sorption and dynamic filtration experiments with a high flux up to 1.30 × 104 L h−1 m−2bar−1. We find that regeneration of the membranes and the metal ion recovery can be facially realized by the treatment using acid solution. These results demonstrate that the developed strategy has significant potential for the design and fabrication of high-performance membranes with hierarchical structures and could find impactful application in the field of industrial catalysis, separation, and environmental pollution control and resources reuse.
Robust Visible Light-Based Positioning Under Unknown User Device Orientation Angle (2018)

In this paper, the localization issue for LiFi users is studied. Due to the nonlinear dependency of received visible light strength on user geometric location parameters, LiFi localization is a non-convex problem and hence it is of great challenge. In order to reduce the problem complexity, previous solutions usually require a known height of user equipment or a perfect alignment of transceiver orientation angles, which limits the application of such solutions. To solve this problem, we propose a novel algorithm to achieve an easy LiFi localization solution without any requirement on perfect alignment transceiver orientations or prior knowledge of user equipment height. By exploring the inherent convex structure of the problem, the proposed algorithm gives an efficient closed-form update equation for both user location and orientation angle, thus achieving an accurate solution with fast convergence rate. The performance of the proposed localization algorithm is verified by simulations, and it is shown that the proposed algorithm can achieve a huge localization performance gain over existing approaches due to the joint optimization of user location and orientation angle as well as the problem-specific parameter update rule design.
MEMS solar sensor testing for satellite applications (2009)

Solar sensors are very common devices used for attitude control of satellites. MEMS technology is very useful to reach the target of reducing the sensor size and cost. We have designed and manufactured a 2 axis analog sun sensor in order to be testing and validated in a real application. The sensor is boarding in the NANOSAT 1B Spanish satellite to be launched in 2009. For several years the satellite and the load devices will be exposed to very hard working conditions. Very accurate calibrating and testing processes have been developed in land to ensure a right performance in orbit. Mechanical, electrical and thermal tests have been applied to the sensor. These tests and its results are discussed In this paper.