gebhart/patrepeval huggingface dataset:
On INM's Use of Corrected Net Thrust for the Prediction of Jet Aircraft Noise (2011)

The Federal Aviation Administration s (FAA) Integrated Noise Model (INM) employs a prediction methodology that relies on corrected net thrust as the sole correlating parameter between aircraft and engine operating states and aircraft noise. Thus aircraft noise measured for one set of atmospheric and aircraft operating conditions is assumed to be applicable to all other conditions as long as the corrected net thrust remains constant. This hypothesis is investigated under two primary assumptions: (1) the sound field generated by the aircraft is dominated by jet noise, and (2) the sound field generated by the jet flow is adequately described by Lighthill s theory of noise generated by turbulence.
Extracellular Vesicles Derived from Gram-Negative Bacteria, such as Escherichia coli, Induce Emphysema Mainly via IL-17A–Mediated Neutrophilic Inflammation (2015)

Recent evidence indicates that Gram-negative bacteria-derived extracellular vesicles (EVs) in indoor dust can evoke neutrophilic pulmonary inflammation, which is a key pathology of chronic obstructive pulmonary disease (COPD). Escherichia coli is a ubiquitous bacterium present in indoor dust and secretes nanometer-sized vesicles into the extracellular milieu. In the current study, we evaluated the role of E. coli-derived EVs on the development of COPD, such as emphysema. E. coli EVs were prepared by sequential ultrafiltration and ultracentrifugation. COPD phenotypes and immune responses were evaluated in C57BL/6 wild-type (WT), IFN-γ-deficient, or IL-17A-deficient mice after airway exposure to E. coli EVs. The present study showed that indoor dust from a bed mattress harbors E. coli EVs. Airway exposure to E. coli EVs increased the production of proinflammatory cytokines, such as TNF-α and IL-6. In addition, the repeated inhalation of E. coli EVs for 4 wk induced neutrophilic inflammation and emphysema, which are associated with enhanced elastase activity. Emphysema and elastase activity enhanced by E. coli EVs were reversed by the absence of IFN-γ or IL-17A genes. In addition, during the early period, lung inflammation is dependent on IL-17A and TNF-α, but not on IFN-γ, and also on TLR4. Moreover, the production of IFN-γ is eliminated by the absence of IL-17A, whereas IL-17A production is not abolished by IFN-γ absence. Taken together, the present data suggest that E. coli-derived EVs induce IL-17A-dependent neutrophilic inflammation and thereby emphysema, possibly via upregulation of elastase activity.
An Ultra Low Power CMOS Photonics Technology Platform for H/S Optoelectronic Transceivers at less than $1 per Gbps (2010)

We have demonstrated a CMOS Optoelectronic technology platform, using a 650mW 4×10-Gb/s 0.13 µm silicon-on-insulator integrated transceiver chip, co-packaged with an externally modulated laser, to enable high density data interconnects at &lt;$1 per Gbps.
P2P cache-and-forward mechanisms for mobile ad hoc networks (2009)

We investigate the problem of spreading information contents in a wireless ad hoc network. In our vision, information dissemination should satisfy the following requirements: (i) it should result in a desirable distribution of information replicas in the network and (ii) the information should be evenly and fairly carried by all nodes in their turn. In this paper, we show that these goals can be achieved by simple cache-and-forward mechanisms inspired by well-known node mobility models, provided that a sufficient number of information replicas are injected into the network. The proposed approach works under different network scenarios, is fully distributed and comes at a very low cost in terms of protocol overhead.
GPU-based timing-aware test generation for small delay defects (2014)

A GPU-based timing-aware ATPG is proposed to generate a compact high-quality test set. The test generation algorithm backtraces and propagates along multiple long paths so that many test patterns are generated at the same time. Generated test patterns are then fault simulated and selected. Compared with an 8-core CPU-based timing-aware commercial ATPG, the proposed GPU-based technique achieved 36% test length reductions on large benchmark circuits while the SDQL quality remains almost the same.
Inhibitors of Fumarylacetoacetate Hydrolase Domain Containing Protein 1 (FAHD1) (2021)

<i>FAH domain containing protein 1</i> (FAHD1) acts as oxaloacetate decarboxylase in mitochondria, contributing to the regulation of the tricarboxylic acid cycle. Guided by a high-resolution X-ray structure of FAHD1 liganded by oxalate, the enzymatic mechanism of substrate processing is analyzed in detail. Taking the chemical features of the FAHD1 substrate oxaloacetate into account, the potential inhibitor structures are deduced. The synthesis of drug-like scaffolds afforded first-generation FAHD1-inhibitors with activities in the low micromolar IC<sub>50</sub> range. The investigations disclosed structures competing with the substrate for binding to the metal cofactor, as well as scaffolds, which may have a novel binding mode to FAHD1.
State-of-the-Art in Handwritten Signature Verification System (2015)

Recently, handwritten signature verification (HSV) has become atremendously active area of research. Considerable results have been achieved in terms of accuracy and computation so far. Generally, biometrics can be divided into two types:Behavioral (signature verification, keystroke dynamics, etc.) and Physiological (iris characteristics, fingerprint, etc.). Signature verification is widely studied and discussed by using two approaches, on-line and offline approaches. Offline systems are more applicable and easy to use in comparison with on-line systems in many parts of the world. However, it is considered more difficult than on-line verification due to the lack of dynamic information. This paper presents State-of-Art about both types of HSV Systems. In this paper, we present recent methods used to capture data as well as different methods and techniques used in pre-processing steps. Additionally, current methods used for features extraction and approaches used for verification in signature systems are presented. Finally, we discuss approaches as well as techniques that have been used. In conclusion, we recommend encouraging ideas to be incorporated in the future.
IRRIGATION SCHEDULINGTO INCREASE WATER UNIT PRODUCTIVITY OF WHEAT-MAIZE ROTATION UNDER CLIMATE CHANGE CONDITIONS (2012)

Irrigation scheduling according to comulated pan evaporationwas used to increase water unit productivity of wheat (Triticumaestivum L.) and maize (Zea mays L.) rotation under two climate changescenarios. Three wheat varieties and two maize hybrids were planted in2-yr field experiments. CropSyst model was calibrated and validated forthe collected field data, then was used to assess the impact of twoclimate change scenarios (A2 and B2) and three adaptation strategies(early sowing changing, irrigation schedule and the interaction betweenthem) in the year of 2038s. The results revealed that A2 reduced yieldmore than B2 scenario for both crops. High yield reduction in wheatmaize rotation could be expected under climate change conditions,where wheat and maize yield will be reduced by an average of 41 and56%, respectively. The most effective adaptation strategy for wheat wassowing 3 wk earlier and irrigation every 21 d, with irrigation watersaving and no yield improvement under A2 scenario in both growingseasons. Whereas under B2 scenario yield improvement by 2%occurred with 3% saving in the applied irrigation water in the 1stgrowing season and in the 2nd growing season yield could improved by8% with less than 1% increase in the applied irrigation water and higherwater productivity. Changing irrigation schedule was an effectiveadaptation option for maize, where yield improvement could occurunder both climate change scenarios in both growing seasons by up to9% with less than 3% increase in the applied irrigation water and higherwater productivity.
One-Step, One-Lane Chemical DNA Sequencing by N -Methylformamide in the Presence of Metal Ions (1996)

We report on a chemical method that allows DNA sequencing by a single reaction. It is based on treatment of 5'-end-labeled DNA with N-methylformamide in the presence of manganese. This method allows the manipulation of samples to be kept to a minimum and consists of a single chemical step that requires about 30 minutes to complete base degradation, phosphodiester bond cleavage and denaturation. Examples of one-treatment, one-lane DNA sequencing of both radioactively and fluorescently 5'-end-labeled DNAs are reported.
Crystal structure of a β-aminopeptidase from an AustralianBurkholderiasp. (2017)

β-Aminopeptidases are a unique group of enzymes that have the unusual capability to hydrolyze N-terminal β-amino acids from synthetic β-peptides. β-Peptides can form secondary structures mimicking α-peptide-like structures that are resistant to degradation by most known proteases and peptidases. These characteristics of β-peptides give them great potential as peptidomimetics. Here, the X-ray crystal structure of BcA5-BapA, a β-aminopeptidase from a Gram-negative Burkholderia sp. that was isolated from activated sludge from a wastewater-treatment plant in Australia, is reported. The crystal structure of BcA5-BapA was determined to a resolution of 2.0 Å and showed a tetrameric assembly typical of the β-aminopeptidases. Each monomer consists of an α-subunit (residues 1-238) and a β-subunit (residues 239-367). Comparison of the structure of BcA5-BapA with those of other known β-aminopeptidases shows a highly conserved structure and suggests a similar proteolytic mechanism of action.
Antibacterial and Antifungal Efficacy of Medium and Low Weight Chitosan-Shelled Nanodroplets for the Treatment of Infected Chronic Wounds (2022)

cNDs exerted bacteriostatic and fungistatic effects, due to the presence of chitosan in the outer shell and independently of oxygen addition in the inner core. The duration of such effects strictly depends on the characteristics of each microbial species, and not on the molecular weight of chitosan in ND shells. However, LW chitosan was better tolerated by human keratinocytes than MW. For these reasons, the use of LW NDs should be recommended in future research to assess cOLND efficacy for the treatment of infected CWs.
Lead: Inorganic Chemistry (2015)

Abstract The article covers basic inorganic chemistry of lead. As an introduction, the properties and historical uses of metallic lead are discussed, followed by aspects of lead toxicity, including the toxicity origins and effects of lead poisoning. Properties of lead as a heavy p‐block element are discussed, with emphasis on the modern view of the so‐called “inert pair effect”, including its origin, the influence on stability of lead oxidation states, and on the coordination chemistry of lead( II ), viz., “sterically active lone pair”. This is followed by an overview of lead inorganic compounds, including halides, pseudohalides, oxides and chalcogenides, hydroxides and their chalcogenide analogs, alkoxides, oxoacids, O‐donors, S‐ and Se‐donors, Group 15 donors, compounds with lead‐transition metal bonds, and finally metallic clusters (Zintl phases). This is by no means a comprehensive review, rather compounds representative for each class were presented. In most sections, structural aspects of each class of compounds are discussed, followed by applications, with the focus on modern uses in material science.
Toxicological effects of ethanol on norepinephrine release and the response of the mammalian iris-ciliary body to pharmacological agents (1998)

There is evidence that chronic alcohol administration can impair pupillary function and response to light. The present study was conducted to establish whether in vivo or in vitro exposure of irides to ethanol could alter sympathetic neurotransmission and the response of the iris to pharmacological agents. The effect of chronic administration of ethanol on sympathetic neurotransmission in rats was examined by studying electrical field-stimulated release of 3 H-norepinephrine ([ 3 H]NE)from iris-ciliary bodies of ethanol-treated and ethanol-naive animals in vitro. Furthermore we investigated the effect of medium to high concentrations of ethanol, applied in vitro, on evoked [ 3 H]NE release from isolated rat, human, bovine and rabbit iris-ciliary bodies. The effect of ethanol was also studied on contractile and relaxant responses of bovine isolated irides to pharmacological agents. In vitro application of ethanol (100 mM) attenuated significantly, the overflow of [ 3 H]NE from iris-ciliary body of rats on a chronic alcohol diet but had no effect on animals on an isocaloric control diet. Ethanol (300 mM) caused more than a five-fold increase in stimulated [ 3 H]NE release from isolated human, rat, bovine and rabbit iris-ciliary bodies. In bovine isolated irides. ethanol (10-100 mM) caused a concentration-dependent attenuation of contractile responses to carbachol and pilocarpine, but had no effect on responses to PGF 2α and potassium chloride. Although, ethanol (100 mM) attenuated relaxant responses of the bovine iris to isoproterenol, relaxations elicited by papaverine were unaffected by this agent. We conclude that ethanol selectively impairs both adrenergic neurosecretion in mammalian iris-ciliary bodies and postjunctional response of bovine irides to pharmacological agents.
Efficient structure from motion on large scenes using UAV with position and pose information (2018)

In this paper, we exploit prior information from global positioning systems and inertial measurement units to speed up the process of large scene reconstruction from images acquired by Unmanned Aerial Vehicles. We utilize weak pose information and intrinsic parameter to obtain the projection matrix for each view. As compared to unmanned aerial vehicles' flight altitude, topographic relief can usually be ignored, we assume that the scene is flat and use weak perspective camera to get projective transformations between two views. Furthermore, we propose an overlap criterion and select potentially matching view pairs between projective transformed views. A robust global structure from motion method is used for image based reconstruction. Our real world experiments show that the approach is accurate, scalable and computationally efficient. Moreover, projective transformations between views can also be used to eliminate false matching.
Optimal Crossover Designs for Logistic Regression Models in Pharmacodynamics (2006)

Pharmacodynamics (PD) is the study of the biochemical and physiological effects of drugs. The construction of optimal designs for dose-ranging trials with multiple periods is considered in this paper, where the outcome of the trial (the effect of the drug) is considered to be a binary response: the success or failure of a drug to bring about a particular change in the subject after a given amount of time. The carryover effect of each dose from one period to the next is assumed to be proportional to the direct effect. It is shown for a logistic regression model that the efficiency of optimal parallel (single-period) or crossover (two-period) design is substantially greater than a balanced design. The optimal designs are also shown to be robust to misspecification of the value of the parameters. Finally, the parallel and crossover designs are combined to provide the experimenter with greater flexibility.
Türkiye’de Cari İşlemler Açığının Sürdürülebilirliği (2016)

Makro ekonomik politikaların nihai amacı bir ülke ekonomisinde iç ve dış dengenin eş anlı olarak sağlanmasıdır. İç dengenin sağlanması ve sürdürülmesi, fiyat istikrarı, tam istihdam ve bununla uyumlu ekonomik büyüme amaçlarına ulaşmayı ifade etmektedir. Dış denge ise ülkenin toplam gideri ile gelirlerinin birbirine denk olması gerektiğini ifade etmektedir. Ülkenin dış ekonomik ilişkilerinin incelenmesinde ve olası sorunların önceden tespitinde cari işlemler hesabı önemli bir rol oynamaktadır. Bu nedenle dış denge cari dengenin sürdürülebilirliği ile ifade edilmektedir. Bu çalışmanın amacı, 1987-2014 yılları arasında Türkiye’de cari açığın sürdürülebilirliğini incelemek olacaktır. Bu çalışmada, cari açıkların sürdürülebilirliğinin test edilmesi için Husted (1992) modeli kullanılmıştır. İhracat ve ithalat arasında uzun dönemli bir ilişkinin olup olmadığı test edilmiştir.
Structural consequences of electron-transfer reactions. Part 12. Multi electron processes involving structural changes. The two-electron reduction of hexaosmium carbonyl cluster (Os6(CO)18) (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructural consequences of electron-transfer reactions. Part 12. Multi electron processes involving structural changes. The two-electron reduction of hexaosmium carbonyl cluster (Os6(CO)18)Bunchai Tulyathan and William E. GeigerCite this: J. Am. Chem. Soc. 1985, 107, 21, 5960–5967Publication Date (Print):October 1, 1985Publication History Published online1 May 2002Published inissue 1 October 1985https://pubs.acs.org/doi/10.1021/ja00307a022https://doi.org/10.1021/ja00307a022research-articleACS PublicationsRequest reuse permissionsArticle Views278Altmetric-Citations53LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A KAP Study of Occupational Exposures to Blood and Body Fluids Among Nursing Staff of Tertiary Level Hospitals of Delhi (2011)

Health care professionals, particularly nursing staff, are at risk of occupational exposure to blood and body fluids. A total of 250 nurses from two similar tertiary level institutions were included in this study which revealed the knowledge, attitudes, and practices of nursing professionals with regard to prevention of occupational exposure to various injuries at their workplace. The type of exposures and their associations with risk behaviors were also analyzed by using logistic regression. Majority of nurses (97.6%) stated that they were aware of the universal work precautions (UWP), but among these, only 59% could correctly define UWP. More than half (54.8%) of nurses recap or manipulate needle after use as a practice. One third (33.2%) of the nurses were ever exposed to blood or body fluids at least once in the past six months, with needle stick injury being the most common type of exposure. Only one tenth of the nurses reported the injury to the authorities. Exposure prevalence was seen to be significantly higher (p<0.001) among those nurses who had either never received, or received a formal training more than two years ago. Practice of always wearing gloves among the study participants was seen as a protective factor from exposures at the workplace. (Adjusted odds ratio = 0.36, 95% C.I. 0.17–0.78). .
Playing the telephone game (2004)

News articles report on facts, events, and opinions with the intent of conveying the truth. However, the facts, events, and opinions appearing in the text are often known only secondor third-hand, and as any child who has played "telephone" knows, this relaying of facts often garbles the original message. Properly understanding the information filtering structures that govern the interpretation of these facts, then, is critical to appropriately analyzing them. In this work, we present a learning approach that correctly determines the hierarchical structure of information filtering expressions 78.30% of the time.
Supplementary Figure 1 from Inhibition of Soluble Tumor Necrosis Factor Prevents Chemically Induced Carcinogenesis in Mice (2023)

&lt;p&gt;Gating strategy for three-color flow cytometry analysis of splenic MDSCs. Splenocytes were simultaneously stained with anti-CD11b-FITC, anti-Gr1-PE and anti-Ly6C-APC antibodies or the corresponding isotype control antibodies and analyzed by flow cytometry as follows. Gate 1: single cells were gated and cell aggregates were excluded. Gate 2: using side-scatter (SSC) and forward-scatter (FSC), granular and non-granular (mononuclear) cells were gated. Gate 3: CD11b+ granular (A) and mononuclear (B) cells were gated. Gate 4: Gr1 and Ly6 expression on CD11b+ granular (A) and mononuclear (B) cells was examined.&lt;/p&gt;
Loss ofCPSF2Expression Is Associated with Increased Thyroid Cancer Cellular Invasion and Cancer Stem Cell Population, and More Aggressive Disease (2014)

Decreased CPSF2 expression is associated with increased cellular invasion and cancer stem cell population, and more aggressive disease in PTC.
Asymmetric-valued Spectrum Auction and Competition in Wireless Broadband\n Services (2013)

We study bidding and pricing competition between two spiteful mobile network\noperators (MNOs) with considering their existing spectrum holdings. Given\nasymmetric-valued spectrum blocks are auctioned off to them via a first-price\nsealed-bid auction, we investigate the interactions between two spiteful MNOs\nand users as a three-stage dynamic game and characterize the dynamic game's\nequilibria. We show an asymmetric pricing structure and different market share\nbetween two spiteful MNOs. Perhaps counter-intuitively, our results show that\nthe MNO who acquires the less-valued spectrum block always lowers his service\nprice despite providing double-speed LTE service to users. We also show that\nthe MNO who acquires the high-valued spectrum block, despite charing a higher\nprice, still achieves more market share than the other MNO. We further show\nthat the competition between two MNOs leads to some loss of their revenues. By\ninvestigating a cross-over point at which the MNOs' profits are switched, it\nserves as the benchmark of practical auction designs.\n
Optimal Measurements and Health Indices Selection for Gas Turbine Performance Status and Fault Diagnosis (1991)

In this paper, we present a method for defining the health estimation parameters and the measurements which must be used, when a monitoring system of an Engine has to be set-up. The particular engine layout, the available measuring instruments and the accuracy by which data can be collected are the factors taken into account. The particular health condition estimation factors, which have to be used, are defined as a function of this information and the desired depth of fault identification. A fast selection procedure based on the method of Singular Value Decomposition is presented. The uncertainty in the estimations is also derived, giving thus an additional element of information useful for decision making. The proposed method together with Adaptive Performance Modelling provides a self sufficient tool, which can be applied for setting up and subsequent exploitation of a health Monitoring Expert System. The advantage of the procedure is that it provides a frame of application, allowing quick implementation in a new engine of interest, other than the ones previously considered.