gebhart/patrepeval huggingface dataset:
[The treatment of women with climacteric symptoms with emphasis on perimenopausal hormone therapy]. (1979)

Guidelines for perimenopausal hormone therapy are listed in outline form. Various symptoms of metabolic changes, of changes in the balance of the neurovegetative system, and of nervous system influences related to social and cultural factors can be treated with substitutive hormone treatment during menopause. Special considerations apply to women who have undergone ovariectomy. Cyclical estrogen treatment should be used, and gestagens should be given in addition to estrogens. In prescribing hormone therapy, all absolute and relative contraindications should be considered. Obese women should be on a strict diet during therapy, and smoking should be stopped. In the case of irregular bleeding, curettage should be performed to exclude the possibility of malignant cancer. The patient should have regular checkups to determine if possible side effects are of a serious nature. Types of medications and treatment regimens for menopausal women, for treating women who have or have not undergone ovariectomy, and for treating menopausal disorders are listed.
Micro-detail detections and their seemingly unrelated scientific inquiries (2013)

This is an introduction of the initial publication of the new Special Section of the MCFNS journal on micro-detail detection and tracking problems and various related interdisciplinary studies in other disciplines, which are deemed to be synergistic or relevant to detection and tracking problems.  The initial selection of publications presented here arose from the Smolensk Conference held on Oct. 22, 2012, in Warsaw, Poland.  This Special Section originated out of a collaboration between the MCFNS editors and the organizers of the Smolensk Conference, but the submissions of the presented here manuscripts was independent from this organization; all authors submitted their manuscripts independently of each other.  This issue contains four of the papers presented at the conference.  In what follows, I briefly review the background behind the creation of this Special Section series and introduce the papers contained herein.
Vector Cryptography System: An Approach for the Analysis of Linear Arithmetic Spaces (2015)

This paper proposes the development of mathematical reasoning in undergraduate students through vector cryptography implemented in a software system. Mathematical reasoning is a cognitive function that could be improved using symmetric encryption techniques such as Hill Cipher, which implements the operations of the linear arithmetic spaces. The goal of this research project is that undergraduate students can learn, understand and apply abstract linear algebra theorems in cryptography context. It is intend to use neurosciences tools to validate the proposed method. The electric brain activity can be measured using electroencephalography (EEG) to obtain neural recruitment while solving complex mathematical problems.
Infant Cereals: Current Status, Challenges, and Future Opportunities for Whole Grains (2019)

Infant cereals play an important role in the complementary feeding period. The aim of this study was to review existing research about the quantity, type, and degree of infant cereal processing, with a special focus on whole grain infant cereals. Accumulating evidence shows many benefits of whole grain consumption for human health. Likewise, consumers are frequently linking the term whole grains to healthiness and naturality, and sustainable food production becomes a more important aspect when choosing an infant cereal brand. Whole grain cereals should be consumed as early as possible, i.e., during infancy. However, there are several challenges that food manufacturers are facing that need to be addressed. Recommendations are needed for the intake of whole grain cereals for infants and young children, including product-labeling guidelines for whole grain foods targeting these age stages. Another challenge is minimizing the higher contaminant content in whole grains, as well as those formed during processing. Yet, the greatest challenge may be to drive consumers' acceptance, including taste. The complementary feeding period is absolutely key in shaping the infant's food preferences and habits; therefore, it is the appropriate stage in life at which to introduce whole grain cereals for the acceptance of whole grains across the entire lifespan.
Disk Drive Roadmap from the Thermal Perspective: A Case for Dynamic Thermal Management (2005)

The importance of pushing the performance envelope of disk drives continues to grow, not just in the server market but also in numerous consumer electronics products. One of the most fundamental factors impacting disk drive design is the heat dissipation and its effect on drive reliability, since high temperatures can cause off-track errors, or even head crashes. Until now, drive manufacturers have continued to meet the 40% annual growth target of the internal data rates (IDR) by increasing RPMs, and shrinking platter sizes, both of which have counter-acting effects on the heat dissipation within a drive. As this paper shows, we are getting to a point where it is becoming very difficult to stay on this roadmap. This paper presents an integrated disk drive model that captures the close relationships between capacity, performance and thermal characteristics over time. Using this model, we quantify the drop off in IDR growth rates over the next decade if we are to adhere to the thermal envelope of drive design. We present two mechanisms for buying back some of this IDR loss with dynamic thermal management (DTM). The first DTM technique exploits any available thermal slack, between what the drive was intended to support and the currently lower operating temperature, to ramp up the RPM. The second DTM technique assumes that the drive is only designed for average case behavior, thus allowing higher RPMs than the thermal envelope, and employs dynamic throttling of disk drive activities to remain within this envelope.
Exogenous (Pomegranate Juice) or Endogenous (Paraoxonase1) Antioxidants Decrease Triacylglycerol Accumulation in Mouse Cardiovascular Disease‐Related Tissues (2018)

The polyphenol-rich pomegranate juice (PJ) and the high-density lipoprotein (HDL)-associated paraoxonase1 (PON1) are known as potent atheroprotective antioxidants, but their effects on other tissues related to cardiovascular disease (CVD) remain unknown. The current study aimed to investigate the effects of treating mice with PJ or recombinant PON1 (rePON1) on the oxidation and lipid status of CVD-related tissues: serum, aorta, heart, liver, kidney, visceral, and subcutaneous adipose tissues (VAT and SAT). Both PJ consumption and rePON1 injection decreased the serum levels of thiobarbituric acid-reactive substances (16% and 19%) and triacylglycerols (TAG, 24% and 27%), while only rePON1 increased the levels of thiol groups (35%) and decreased serum cholesterol (15%). Both PJ and rePON1 significantly decreased aortic cholesterol (38% and 32%) and TAG (62% and 58%) contents in association with downregulation of the key TAG biosynthetic enzyme diacylglycerol O-acyltransferase 1 (DGAT1, 71% and 65%), while only PJ decreased aortic lipid peroxides (47%). Substantial TAG-lowering effects of both PJ and rePON1 were observed also in the heart (31% and 42%), liver (34% and 42%), and kidney (42% and 57%). In both VAT and SAT, rePON1 decreased the levels of lipid peroxides (28% and 25%), while PJ decreased the TAG content (22% and 18%). Ex vivo incubation of SAT with serum derived from mice that consumed PJ or injected with rePON1 decreased SAT lipid peroxides (35% or 28%) and TAG mass (12% or 10%). These novel findings highlight potent TAG-lowering properties of exogenous (PJ) and endogenous (PON1) antioxidants in tissues associated with CVD.
Detection of airborne industrial papain by a radioimmunoassay (1981)

Abstract A method for measuring papain, an extract of Carica papaya, in the ambient air of an industrial setting was developed using a modified radioallergosorbent test. Papain in air samples was collected and insolubilized by coupling with cyanogen bromide activated cellulose particles. The coval-ently bound papain was measured by incubating the conjugate with anti-papain antibodies of the immunoglobulin E class (IgE) and anti-IgE-I125. Binding of the radiolabel was directly proportional to the concentration of papain in the conjugate. The sensitivity of the test was such that a minimum of 5 nanograms of papain was reliably measured. Based on sampling conditions, the procedure was capable of measuring concentrations of papain as low as 5 pico-grams per cubic meter of air without dependence on the enzymatic properties of the protease.
Green approaches to the production of iopamidol (2011)

Iodinated contrast agents, such as iopamidol, are worldwide employed for performing a number of X-ray diagnostic procedures. Every year, thousands of tons of iodinated contrast agents are manufactured for the market with chemical processes that usually employ thionyl chloride. In this paper, we describe two new green approaches to iopamidol that avoid or reduce the use of this noxious reagent.
Selective Binding of Zn 2+ Complexes to Non‐Canonical Thymine or Uracil in DNA or RNA (2014)

This chapter discusses Zn2+ macrocyclic complexes that bind to DNA and RNA with an emphasis on the recognition of non-canonical deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) structures. It discusses additional considerations of the important energetic factors contributing to binding. The chapter describes the recognition of two common types of structures that involve non-canonical thymine or uracil. It focuses on, using structural information from nuclear magnetic resonance (NMR) spectroscopy to rationalize the selectivity of binding of monomelic Zn2+ complexes to thymine bulges in DNA. The chapter also focuses on binding interactions of Zn2+ complexes that contain a pendent two-ring aromatic group. These complexes have the highest selectivity for binding to non-canonical thymine in DNA or uracil in RNA bulges. An additional consideration is that selectivity toward non-canonical thymine or uracil may be improved by decreasing binding strength of Zn2+ complexes to double-stranded DNA or RNA, respectively.
Calculated electronic and magnetic structure of screw dislocations in alpha iron (2011)

Local atomic magnetic moments in crystalline Fe are perturbed by the presence of dislocations. The effects are most pronounced near the dislocation core and decay slowly as the strain field of the dislocation decreases with distance. We have calculated local moments using the locally self-consistent multiple scattering (LSMS) method for a supercell containing a screw-dislocation quadrupole. Finite size effects are found to be significant indicating that dislocation cores affect the electronic structure and magnetic moments of neighboring dislocations. The influence of neighboring dislocations points to a need to study individual dislocations from first principles just as they appear amid surrounding atoms in large-scale classical force field simulations. An approach for the use of the LSMS to calculate local moments in subvolumes of large atomic configurations generated in the course of classical molecular dynamics simulation of dislocation dynamics is discussed.
Fish oil-enriched diet is mucosal protective against acetic acid-induced colitis in rats (1991)

Products of arachidonic acid metabolism are elevated in patients with inflammatory bowel disease and this elevation is correlated with disease activity. Eicosapentaenoic acid competes with arachidonic acid and alters eicosanoid biosynthesis. In this experiment, the possibility that eicosapentaenoic acid could be used in the treatment of inflammatory bowel disease was investigated by determining the effect of 6 weeks of a fish oil-supplemented diet, enriched in eicosapentaenoic acid, on colonic and ileal morphology, histology, and in vivo fluid absorption in rats with 4% acetic acid-induced colitis. The results of an eicosapentaenoic acid-enriched diet were compared with results of saturated and polyunsaturated fatty acid-enriched diets. In rats with misoprostol pretreated acetic acid-induced colitis, an eicosapentaenoic acid-enriched diet reversed net colonic fluid secretion to absorption and prevented macroscopic and histologic injury, compared with saturated and poly-unsaturated fatty acid-enriched diets, which did not. The fish oil mucosal protective effect occurred in the presence of a 30-fold enhancement of PGE2 synthesis. In rats with non-misoprostol pretreated acetic acid-induced colitis, an eicosapentaenoic acid-enriched diet returned ileal fluid absorption to control levels, as compared with saturated and polyunsaturated fatty acid-enriched diets, which did not. In conclusion, a fish oil (eicosapentaenoic acid)-enriched diet, but not a saturated- or a polyunsaturated-enriched diet, protected colonic and ileal net fluid absorption in an experimental model of inflammatory bowel disease.
On the Reactivity of Halo-1,3-azoles and Related Compounds toward Aromatic SN2 Substitution (1990)

Nucleophiltc addition-elimination 8-eactions of ?--methylsulfonyi-1.3-azoleswith active methylene compounds were investigated in order Lo compare the reactivity of substrates.The order o f oxazole > ttiiazoie > 3-methylimidazale in the reacLivity was exhlbiled clearly.Furll~ermore, in axazuie and thiazc>le series, the predominant reactivity of the 2-position Over the 4 -and 5-positinns was indicated on the reaction with the carbanions generated from active methylene compounds.Synthesis of 1.3-azolr derivatives containing a functionaiized c a r b o n side-chain by means of aromatic SN2 type substitution of monohalo-1.3-azoies with active methylene compounds under basic conditions has not yet been well invest~gated, nnd t h e fol loving only two reactions are reported in this category."'
Registration of the S2MET Barley Mapping Population for Multi‐Environment Genomewide Selection (2019)

Market changes in the malting and brewing industries have increased the demand for locally produced barley ( Hordeum vulgare L.) in many regions across North America. Breeding for productive barley cultivars in diverse growing environments is complicated by genotype × environment interactions (GEIs), which can make selection for broad adaptation difficult but may be exploited to select optimal cultivars for each environment. Genomewide selection has recently become a useful tool to make efficient selections on individuals using genomewide marker data. To support the use of genomewide selection to breed locally adapted barley cultivars, the University of Minnesota barley breeding program is publicly releasing a panel of two‐row barley lines, and accompanying data, called the S2MET (Spring Two‐Row Multi‐Environment Trial) (Reg. No. MP‐2, NSL 526938 MAP). The S2MET includes 233 breeding lines grouped into a 183‐line training population and a 50‐line validation population. The entire panel was genotyped using genotyping‐by‐sequencing and phenotyped for 14 important traits in 44 location‐year environments between 2015 and 2017. All data are freely available at the Triticeae Toolbox ( https://triticeaetoolbox.org/barley/ ), and we describe several on‐tap projects and breeding advances that are exploiting this resource. We believe this panel and dataset will be useful for answering important breeding questions related to genomewide selection and GEIs and developing locally superior barley cultivars.
Full-coverage multichannel wavelength-monitoring circuit for WDM system (1998)

Summary form only given. We have designed and fabricated a multichannel wavelength-monitoring circuit using a specially designed center-offset phased-array waveguide grating. The monitoring circuit can cover the whole wavelength range of 8 nm in the WDM system without any blind range.
Accumulation of Reservoir Fluids: ABSTRACT (1968)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
Selective hydrogenation of furfural to tetrahydrofurfuryl alcohol over a Rh-loaded carbon catalyst in aqueous solution under mild conditions (2019)

We describe the selective hydrogenation of furfural (FAL) into tetrahydrofurfuryl alcohol (THFA) under mild conditions (30 °C) in aqueous media using a Rh-loaded carbon (Rh/C) catalyst in a one-pot fashion.
Recordings of Bioelectric Potentials with Glass Microelectrodes: Limitations of Unity-Gain Follower with Buffer (1976)

It is possible to design amplifiers with virtually no input capacitance. As shown in the sequel, this feature, however, is not by itself sufficient to insure faithful recording of fast transmembrane potentials with glass microelectrodes.
Osteogenic Potential of Fast Set Bioceramic Cements: Molecular and In Vitro Study (2020)

Recently, pre-mixed bioceramics in fast set formulations have been increasingly utilized in clinical practice as an alternative to mineral trioxide aggregate (MTA) for their shorter setting time and better handling properties. However, the impact on their osteogenic potential, due to modifications in chemical composition to promote a fast setting, is still unclear. This molecular and in vitro study compared the osteogenic potential of root repairing material putty fast set (FSP) with root-repairing material putty (RRMPU), root-repairing material paste (RRMPA), Biodentine™ and MTA. The null hypothesis tested was that there are no differences among the tricalcium silicate materials in terms of osteogenic potential. Standardized discs were cultured with MG-63 human osteoblastic-like cells to assess biocompatibility, the activity of alkaline phosphatase (ALP) and osteogenic potential. Biocompatibility was evaluated at baseline and after 24 and 48 h. Osteogenic differentiation was assessed after 15 days. Data were analyzed with one-way ANOVAs and Tukey’s post-hoc test (p &lt; 0.05). All materials showed biocompatibility and bioactivity. ALP activity, which induces mineral nodule deposition, increased in all the cements tested, with a significant increase in RRMPU (p &lt; 0.001) and FSP (p &lt; 0.001) samples versus MTA. In vitro mineralization was significantly increased for RRMPU (p &lt; 0.0001), FSP (p = 0.00012) and Biodentine™ (p &lt; 0.0001) versus MTA. The bioceramics tested showed higher levels of biocompatibility and bioactivity than MTA; a higher capacity for mineralization was observed with RRMPU and FSP versus MTA.
On the sample‐complexity of ℋ∞ identification (2001)

Abstract In this paper we derive the sample complexity for discrete time linear time‐invariant stable systems described in the ℋ︁ ∞ topology. The problem set‐up is as follows: the ℋ︁ ∞ norm distance between the unknown real system and a known finitely parameterized family of systems is bounded by a known real number. We can associate, for every feasible real system, a model in the finitely parameterized family that minimizes the ℋ︁ ∞ distance. The question now arises as to how long a data record is required to identify such a model from noisy input–output data. This question has been addressed in the context of l 1 , ℋ︁ 2 and several other topologies, and it has been shown that the sample‐complexity is polynomial. Nevertheless, it turns out that for the ℋ︁ ∞ topology the sample‐complexity in the worst case can be infinite. Copyright © 2001 John Wiley &amp; Sons, Ltd.
A Method for the Verification of Wire Crimp Compression Using Ultrasonic Inspection (2010)

The development of a new ultrasonic measurement technique to assess wire crimp terminations is discussed. The amplitude change of a compressional ultrasonic wave propagating at right angles to the wire axis and through the junction of a crimp termination is shown to correlate with the results of a destructive pull test. The case of incomplete compression of crimped connections is ultrasonically tested, and the results are correlated with pull tests. Results show that the ultrasonic measurement technique consistently predicts good crimps when the ultrasonic transmission is above a certain threshold amplitude level. A quantitative measure of the quality of the crimped connection based on the ultrasonic energy transmitted is shown to respond accurately to crimp quality. A wave propagation model, describes the compressional ultrasonic wave propagation through the junction during the crimping process. This model is in agreement within 6% of the ultrasonic measurements. A prototype instrument for applying this technique while wire crimps are installed is also presented. The instrument is based on a two-jaw type crimp tool suitable for butt-splice type connections. A comparison of the results of two different instruments is presented and shows reproducibility between instruments within a 95% confidence bound.
INTRALESIONAL BLEOMYCIN IN TREATMENT OF PLANTAR WARTS (2019)

Objective: To assess the efficacy of intralesional bleomycin in treating plantar warts. Study Design: Descriptive cross-sectional study. Place and Duration of Study: Combined Military Hospital Lahore, from Jan 2015 to Sep 2015. Material and Methods: The study was conducted in Dermatology outpatient department, Combined Military Hospital Lahore, from Jan 2015 to Sep 2015. Total of 60 plantar warts in 20 patients were treated with 1 mg/ml intralesional injection of bleomycin. Patients received a total of four doses of bleomycin every three weeks, and were followed for next three months. We categorized the response to treatment as complete or partial resolution, and nonresponsive. Results: Out of 60 warts 46 warts (76.66%) showed complete resolution and 8 (13.33%) warts showed partial resolution (p<0.001). The cure rate was better in warts smaller than 20 mm in diameter in comparison with larger lesions. After six months follow-up, 3 (15%) of the completely resolved warts showed recurrence. Recurrence was more among those with greater number of warts. Conclusion: Intralesional bleomycin injections were found to be a reliable, safe and acceptable mode of treatment for plantar warts.
The Impact of Marketing Channels Used by U.S. Meat Goat Producers on Farm Profitability (2014)

This study investigates factors influencing the use of marketing channels in U.S. meat goat production. Producer demographics, production system, socioeconomic, and regional variables impacted marketing channel selection. Larger-scale producers selling goat meat or selling larger percentages of goats as slaughter or as meat were more profitable.
In-situ monitoring of etch uniformity using plasma emission interferometry (2015)

A method for in-situ real-time monitoring of the etch uniformity of a dielectric film during plasma etching in a restricted geometry is reported. The method is based on interferometry using the natural plasma emission as the light source. Interference patterns are created by light reflections at the Brewster angle between the electrodes of parallel-plate capacitively coupled plasma reactors with small interelectrode gap. The method can be useful as a monitor for statistical process control.
Expression of human ERG K channels in the mouse heart exerts anti-arrhythmic activity (2004)

HERG expression in the mouse heart can protect against experimental induction of arrhythmias. This is the first report of such a protective effect of HERG in vivo.