gebhart/patrepeval huggingface dataset:
Capacitive feeding for slotted microstrip patch (2011)

A Microstrip patch antenna having slotted sides with small capacitive feed has studied and discussed here. Slots on the proposed patch can be used to increase the bandwidth of antenna. It has observed that VSWR bandwidth nearly 45% can be easily achieved with the novel patch. A constant radiation pattern with improved bandwidth, for an operating frequency of 4.8 GHz can be easily achieved. Configuration of an antenna is easy to design. A very small feed strip is placed very close to the presented novel patch on the substrate above the ground plane. The given patch is act as radiating patch while feed strip couples the energy to radiating patch by capacitive mean. The model of antenna incorporates the capacitive feed strip which is fed by a coaxial probe by using equivalent approach. Effect of various parameters such as air gap between the substrate and the ground plane, probe diameter, the distance between the radiator patch and feed strip, and dimensions of the feed strip on the performance of the antenna has studied and there results has discussed here. A proposed patch can be used for various application in L-, S-, C- or X-band.
Thermoelectric Properties of Ge-Rich GeSn Films Grown on Insulators (2016)

We investigate incorporation effects of p-type dopant (B or Al) on the growth characteristics, electrical and thermoelectric properties of Ge-rich polycrystalline (poly-) Ge 1-x Sn x (x&lt;0.02) films on SiN crystallized by solid-liquid coexisting annealing in the temperature range of 500-700 o C. XRD analyses demonstrate that a larger grain size can be achieved for GeSn samples with an initial Sn content of 2% and Al-doped samples compared with Ge samples and B-doped samples, respectively. In analyses of electrical and thermoelectric properties, we found that B-doped samples have a larger electrical conductivity and Seebeck coefficient, which corresponds to higher carrier concentration in the poly-Ge 1-x Sn x films compared with the others. As a result, a maximum power factor of ~1 mW/K 2 cm is obtained for a B-doped sample, which value is comparable or better than that for undoped Ge 1-x Sn x films (0.045&lt;x&lt;0.123) epitaxially grown on Ge(001).
Electrochemical and Stress Corrosion Cracking Behavior of Digester Steels in Kraft White Liquors (1985)

Stress corrosion cracking (SCC) of ASTM A516 Grade 70 and A285 Type C steels was found to occur in a simulated white liquor containing 90 g/L NaOH + 35 g/L Na2S. Cracking in constant potential slow strain rate (SSR) experiments was found to occur at potentials near the active-passive transition of the steel at 90 and 110 C. Cracking was also observed for both steels at a potential of −1200 mVSCE. Criteria developed by Parkins20,21 from fast and slow scan polarization curves to predict the potential range of SCC were found to be inappropriate for use in simulated white liquor. Two distinct potential regions of passive film formation were identified from anodic polarization curves. The formation of sulfide-containing films was associated with potentials near −900 mVSCE. and the formation of hydroxide-containing films was associated with potentials near −1100 mVSCE. Cracking in SSR experiments occurred within the former region, but not in the latter. Additions of NaCl, Na2CO3, and Na2S2O3 had little measurable effect on the anodic polarization behavior of the steels, nor were any differences noted between curves produced with ASTM A516 Grade 70 and A285 Type C steels or with AWS(1) E7018 weld metal.
Nonhomogeneous force application during typical flutter ablation explains local difficulties in lesion creation (2021)

Introduction – The current scientific literature suggests similar or even better catheter contact on caval regions of the cavo-tricuspid isthmus (CTI) compared to the more medial or annular part. Yet CTI ablation can be challenging owing to instability at the inferior vena cava (IVC) edge. No study specifically addressed the issue of catheter-tissue contact on caval/mid/annular regions of the CTI. Methods – Twenty-seven patients (22 men, 67±12 years) underwent typical atrial flutter ablation with a contact force (CF) sensing catheter (Tacticath 75, Abott) and were prospectively included. Operators aimed at optimizing CF for all RF pulses. The product of CF, time (force-time integral; FTI) and delivered power (FTPI) has been proposed as an estimate of lesion size. In a subset of 8 consecutive pts, electrograms (EGM) of all RF lesions were analyzed. Annular CTI was defined as sites showing both atrial and ventricular near-field bipolar EGM. Mid CTI sites had only atrial near field bipolar EGM on both distal and proximal dipoles (or distal only in case of superior-to-inferior approach). Caval sites had near-field bipolar EGM only in distal dipole, while the proximal one was inferiorly located. Results – Complete persistent (at 30 min) CTI block was obtained in all patients. A steerable sheath was used in 12 pts (44%). Procedure duration was 93±30 min, RF delivery time 10±6 min, fluoroscopy time 14±8 min. Mean CF was 15.8±5.9 g. CF was significantly lower (11.1±9.7 g) at the caval CTI than at mid CTI (19.9±11.8 g) and annular CTI (20±12.2 g; p=0.001). CF and FTI were higher during sinus rhythm than during Fl (23.2±15.3 vs 18.5±15.4 g, p=0.04 and 677±432 vs 532±357 gs, p=0.03). Use of a sheath improved mean CF (24.4±12.5 vs 18.4±14.9 g, p=0.01) but this was not significant at caval sites (17.5±11.4 vs 12.6±10.7 g, p=0.31). Conclusion – Applied forces are significantly lower at the IVC edge during CTI ablation. This supports the use of a steerable sheath in challenging cases.
Performance optimization for unmanned vehicle systems (2008)

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Aeronautics and Astronautics, 2008.
Adult Turner syndrome associated with chylous ascites and vascular anomalies (1987)

An adult female with Turner syndrome presented with severe lymphedema and chylous ascites. In addition, the patient was found to have a right-sided aortic arch and a left-sided inferior vena cava. Although lymphedema is common in infants with Turner syndrome is previously unreported. In this patient, a peritoneo-venous shunt appeared to be beneficial.
‘THE PURPLE YEAR’ IN POPE AND GRAY (1963)

‘THE PURPLE YEAR’ IN POPE AND GRAY ARTHUR JOHNSTON ARTHUR JOHNSTON Search for other works by this author on: Oxford Academic Google Scholar The Review of English Studies, Volume XIV, Issue 56, 1963, Pages 389–393, https://doi.org/10.1093/res/XIV.56.389 Published: 01 October 1963
Timing Treatments for Apple Maggot (Diptera: Tephritidae) Control Using Sticky Sphere Traps Baited with Synthetic Apple Volatiles (1987)

Weak relationships between larval damage and adult catch were observed for apple maggot, Rhagoletis pomonella (Walsh), in untreated dwarf, semidwarf, and standard apple trees, using red sticky sphere traps baited with synthetic apple volatiles. Traps were sensitive in detecting adults. Fruit among the canopy quadrants were uniformly infested, which indicated that the baited traps were not causing an aggregation of the damage within the canopy. Studies using the baited traps for timing apple maggot control treatments in commercial orchards demonstrated that commercially acceptable levels of control could be obtained using a catch threshold of two adults per trap. Adult catches were not accumulated for the threshold until 12 d after a treatment. With this threshold, 46% fewer treatments (1.9 fewer applications) were applied than in a calendar-based program. Results indicated that a threshold as high as five adults per trap might be used.
Nonlinear H-infinity Control applied to a UAS in Trajectory Following (2015)

Solution of a Hamilton –Jacobi-Isaacs’s equation which is derived from the passivity and L2 gain concepts is approximated using a Taylor series expansion. This solution provides a nonlinear version of H-infinity controller. This work presents performance assessment of a third order expansion robust nonlinear controller and compares it with a second order version, an output feedback linear robust controller. A significant improvement is obtained by adding the third term when controlling an autonomous aerial vehicle in a trajectory following.
Anomalous First Breakdown Behavior for HFO1234ze(E) (2021)

Environmentally friendly gases have been widely investigated to replace sulphur hexafluoride (SF6) in compressed gas insulated equipment for the power industry. This work presents the experimental investigations on the gas stability of HFO1234ze(E) (hereinafter referred to as C <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</inf> H <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> F <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</inf> ) where a unique first breakdown voltage behavior is found for AC, DC and lightning impulse (LI) voltages. A splatter of dark colored soot is observed on the plane electrode after the first breakdown that is followed by consecutive LI breakdowns chopped on the front. The breakdown characteristic stabilizes after the first voltage withstand and the 50% breakdown voltage (U <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">50</inf> ) is calculated using the subsequent stabilized data series. This first breakdown behavior of C <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</inf> H <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> F <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</inf> is consistently observed for different tested electrode materials and configurations. The voltage difference between the first breakdown and U <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">50</inf> varies significantly due to the work function of the electrode material and electric field uniformity. For AC breakdowns with comparatively higher discharge energy, the data series is more consistent after the first breakdown but with significant level of soot formation indicating that this is the main influencing factor for the first breakdown effect. Soot is identified as fluorinated carbon through X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS) analyses.
Evolving Role of Genomics in Genitourinary Neoplasms (2019)

The aim of this article is to review the current role of genomic testing in the risk, prognosis, and treatment of genitourinary malignancies. The authors selected guidelines, publications, and abstracts relevant to the current and emerging role of genomics in genitourinary cancers. The risk of developing genitourinary cancer can be stratified based on genomic data. Prostate cancer has the strongest degree of heritability, with BRCA1/2 and HOXB13 mutations playing a role in familial disease. Genomic data is on the verge of informing treatment decisions across genitourinary cancers. mCRPC has diverse genomic alterations that represent potential therapeutic targets, including alterations in the AR pathway, DNA damage and repair pathways, cell cycle pathways, PI3K pathway, and Wnt signaling. Genomic alterations in clear cell renal cell carcinoma can inform prognosis and mutations in mTOR pathways predict response to mTOR inhibitors. Urothelial carcinoma can be classified into different subtypes based on gene expression profiling, which provides prognostic information and predicts response to chemotherapy and immunotherapy. Specific mutations have been identified that predict response to therapy including ERCC2 mutations and cisplatin, DNA damage and repair mutations and checkpoint inhibitors, and FGFR3 mutations and FGFR tyrosine kinase inhibitors such as erdafitinib. CONCLUSION: Genitourinary malignancies have not felt the impact of genomic data as greatly as other cancer types. The majority of benefit lies in identifying patients at high risk of genitourinary cancer. Fortunately, breakthroughs are on the horizon that will result in a greater incorporation of genomic information into treatment decisions for patients with genitourinary cancer.
MBARS2: A New Design for a 3- Degrees of Freedom Parallel Structure for Joint Arthroplasty (2008)

In this report we present the second prototype of a 3-degrees-of-freedom active, miniature bone-attached, robotic system. The report focuses on the mechanical structure, workspace analysis and inverse kinematics solution. The robot is capable of preparing the bone cavity for an implant during joint arthroplasty procedures. This system, just as its predecessor is image-free and all planning is performed intraoperatively in the robot coordinate system, eliminating the need for external tracking systems in the OR. Experiments were conducted using the first robot prototype to evaluate its accuracy and the results supported the feasibility of the concept.
A Method for the Conceptual Design of Hybrid Electric Aircraft (2019)

The growing interest into hybrid electric propulsion as a possible solution to reduce in-flight emissions has led to the investigations of many innovative propulsive system architectures that couple higher system efficiency with improved aerodynamic propulsion integration strategies. The paper presents amethodology to model and size generic hybrid electric propulsion system at the conceptual level allowing for a rapid exploration of the vast design space. The generalization of the propulsive system using a basic propulsive power unit object is discussed highlighting the control parameters needed to fully define the propulsive system architecture. Three case studies for a 2035 turbo-prop regional aircraft using parallel, series/parallel and distributed series configurations showthat improvements to the fuel and energy consumption are affected by the system morphology, its control strategy and the maturity level assumed for its components. Using conservative estimations for the battery and electric components performances indicate that the best configurations can only provide a fuel reduction of around 5% while weighting 25% more than the reference design. Using more optimistic assumptions leads to a larger feasible design space where the best performing configuration, the series/parallel one, realizes more substantial fuel and energy reductions of 28% and 14% with a 24% higher take-off mass.
Aptamers as Therapeutic Tools in Neurological Diseases (2016)

Nucleic acid aptamers have attracted considerable attention as tools for targeted molecular recognition. This chapter describes advances in aptamer technology in the field of neurological diseases. Aptamers possess certain advantages over antibodies, such as stability, production scale, method and time, chemical fabrication, and costs. Multiple sclerosis is a chronic inflammatory and demyelinating disorder of the nervous system. A combination of these aptamers with other therapeutics payload might improve the overall treatment efficacy of glioblastoma cells significantly. Thrombolysis-related hemorrhage is one of the major obstacles in the development of stroke treatments, because new therapeutics needs to be immediately reversible in case of hemorrhage occurrence. Parkinson disease is a neurodegenerative disorder of the central nervous system, mainly affecting the motor neuron system. Alzheimer disease is the most common neurodegenerative disease and is accountable for more than 80% of all cases of dementia in the elderly. Myasthenia gravis is a disease that interferes with the signal transduction between neurons and muscle cells.
Clinical Applications for Vitamin D Assays: What Is Known and What Is Wished for (2011)

Vitamin D is a “hot topic,” with the number of citations in PubMed exceeding 2400 in 2009, a 3-fold increase in 1 year. In the US, the number of requested 25-hydroxyvitamin D (25-OHD)9 assays is increasing exponentially. Not all of the published material has validity, however. A panel of experts was invited to address a series of questions pertaining to laboratory methods and clinical applications of available assays for 25-OHD and 1,25-dihydroxyvitamin D (1,25-OHD).

What should we measure: 25-OHD3, 25-OHD2, both, or 1,25-OHD? 

Rosemary L. Schleicher: Our interest is in providing 25-OHD data for the National Health and Nutrition Examination Survey (NHANES). Separate estimates for 25-OHD2 and 25-OHD3—together with recent food- and supplement-intake data, questionnaire data about physical activity, sun-protection behavior and skin type, and demographic information related to race/ethnicity, season, latitude, and age—provide valuable information about the sources of vitamin D for those in the noninstitutionalized civilian US population. In addition, we will be separating and quantifying the C3 epimer of 25-OHD3, which may not be as biologically active as 25-OHD3.



John Eisman: 25-OHD2 and 25-OHD3 should be measured in most clinical situations, although in many countries vitamin supplements and food fortification are moving from vitamin D2 to D3. I am unaware of clinical needs requiring knowing 25-OHD2 and 25-OHD3 separately, or the C3 epimer. There are few clinical situations where knowing the 1,25-OHD concentrations are clinically critical or overly helpful.



Roger Bouillon: We need to know the combined concentration of 25-OHD3 and 25-OHD2 because both products can be converted into the active hormone 1,25-OHD. In countries where vitamin D2 supplementation is not available, the measurement of 25-OHD3 alone would be sufficient, since there is very …
Tetrakis(tetramethylammonium) Dihydrogendecavanadate Acetic Acid 2.8-Hydrate, [N(CH3)4]4[H2V10O28].CH3COOH.2.8H2O (1998)

The title compound was synthesized and found to crystallize in the triclinic space group P\overline{1}. The decavanadate cluster with two H atoms, [H2V10O28]4−, forms layers by hydrogen bonding with acetic acid and water of crystallization. The tetramethylammonium cations fill space between the layers.
Benefit and Safety of Enhanced External Counterpulsation in Treating Coronary Artery Disease Patients with a History of Congestive Heart Failure (2001)

Enhanced external counterpulsation (EECP) is used to noninvasively treat refractory angina patients, including those with a history of heart failure. The International EECP Patient Registry was used to examine the benefit and safety of EECP treatment, including a 6-month follow-up, in 1,957 patients, 548 with a history of heart failure. The heart failure cohort was older, with more females, a greater duration of coronary artery disease, more prior infarcts and revascularizations. Significantly fewer heart failure patients completed the course of EECP, and exacerbation of heart failure was more frequent, though overall major adverse cardiac events (MACE, i.e. death, myocardial infarction, revascularization) during treatment were not significantly different. The angina class improved in 68%, with comparable quality of life benefit, in the heart failure cohort. At 6 months, patients with congestive heart failure maintained their reduction in angina but were significantly more likely to have experienced a MACE end point.
Analysis of gamma-aminobutyric acidB receptor function in the in vitro and in vivo regulation of alpha-melanotropin-stimulating hormone secretion from melanotrope cells of Xenopus laevis (1993)

The activity of many endocrine cells is regulated by gamma-aminobutyric acid (GABA). The effects of GABA are mediated by GABAA and/or GABAB receptors. While GABAB receptors in the central nervous system have now been extensively characterized, little is known of the function and pharmacology of GABAB receptors on endocrine cells. In the amphibian Xenopus laevis, GABA inhibits the release of alpha MSH from the endocrine melanotrope cells through both GABAA and GABAB receptors. We have investigated the following aspects of the GABAB receptor of the melanotrope cells of X. laevis: 1) the pharmacology of this receptor, using antagonists previously established to demonstrate GABAB receptors in the mammalian central nervous system; 2) the relative contribution to the regulation of hormone secretion by the GABAA and GABAB receptors on melanotrope cells in vitro; and 3) the role of the GABAB receptor with respect to the physiological function of the melanotrope cell in vivo, i.e. regulation of pigment dispersion in skin melanophores in relation to background color. Our results demonstrate that phaclofen, 2-hydroxysaclofen, and 4-aminobutylphosphonic acid dose-dependently blocked the inhibition of alpha MSH release by GABAB receptor activation, but not by GABAA receptor activation. The GABAB receptor antagonist delta-aminovaleric acid appeared to be a selective agonist on the GABAB receptor of melanotrope cells. The inhibitory secretory response to a low dose of GABA (10(-5) M) was not affected by bicuculline, but was significantly reduced by phaclofen, indicating that at a low GABA concentration, the GABAB receptor mechanism would dominate in inhibiting the melanotrope cells. Different thresholds of activation may form the basis for differential action of GABA through both GABA receptor types. The tonic inhibition of alpha MSH release in animals adapted to a white background was not affected by 4-aminobutylphosphonic acid, indicating that the GABAB receptor is not (solely) involved in the in vivo inhibition of alpha MSH release in animals on a white background.
Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes (2019)

Abstract Anti-CRISPRs (Acrs) are small proteins that inhibit the RNA-guided DNA targeting activity of CRISPR-Cas enzymes. Encoded by bacteriophage and phage-derived bacterial genes, Acrs prevent CRISPR-mediated inhibition of phage infection and can also block CRISPR-Cas-mediated genome editing in eukaryotic cells. To identify Acrs capable of inhibiting Staphylococcus aureus Cas9 (SauCas9), an alternative to the most commonly used genome editing protein Streptococcus pyogenes Cas9 (SpyCas9), we used both self-targeting CRISPR screening and guilt-by-association genomic search strategies. Here we describe three new potent inhibitors of SauCas9 that we name AcrIIA13, AcrIIA14 and AcrIIA15. These inhibitors share a conserved N-terminal sequence that is dispensable for anti-CRISPR function, and have divergent C-termini that are required in each case for selective inhibition of SauCas9-catalyzed DNA cleavage. In human cells, we observe robust and specific inhibition of SauCas9-induced genome editing by AcrIIA13 and moderate inhibition by AcrIIA14 and AcrIIA15. We also find that the conserved N-terminal domain of AcrIIA13-15 binds to an inverted repeat sequence in the promoter of these Acr genes, consistent with its predicted helix-turn-helix DNA binding structure. These data demonstrate an effective strategy for Acr discovery and establish AcrIIA13-15 as unique bifunctional inhibitors of SauCas9.