gebhart/patrepeval huggingface dataset:
Inverse Transonic Wing Design Method (1981)

An inverse, transonic flow method for the design of three-dimensi onal wings has been developed. The flow method is based on a three-dimensional, finite-differ ence solution of the full-potential equation. The inverse scheme utilizes a Dirichlet boundary condition in conjunction with surface transpiration to affect geometry definition. Such a scheme has previously been utilized in a two-dimensional method. This paper summarizes an analogous development for three dimensions. Basic steps and underlying assumptions of the inverse scheme are described. Applications of the method to both simple and complicated design problems are discussed and advantages of the method are identified.
Early Prospective Clinical Results of a Modern Fixed-Bearing Total Ankle Arthroplasty (2013)

Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Metabolic Approaches to the Treatment of Back Pain (2018)

Back pain is the most common cause of disability worldwide. Back pain is among the orthopedic conditions that occur when biomechanical forces exceed the patient's metabolic wherewithal to withstand the forces, heal, and manage pain signaling. This chapter aims to help healthcare providers deepen and broaden their awareness of treatable metabolic antecedents of back pain. It uses the functional medicine framework to ascertain and organize patient-specific findings and implement individualized treatment strategies. Functional Medicine is the clinical application of systems biology. Functional Medicine sees health and illness along a continuum that changes over time. Traditionally, the treatments for back pain include anti-inflammatory medications, muscle relaxants, opioids, and physical therapy. In certain patients, interventional treatments such as dry needling, trigger point injections, medial branch and dorsal rami radiofrequency ablation, and even surgery can be a necessary component of a treatment strategy.
Prevalence of treatment-resistant depression in primary care: cross-sectional data (2013)

The high prevalence of TRD is an important challenge facing clinicians in UK primary care. A more proactive approach to managing this patient population is required to improve outcome.
Beyond tissueInfo: functional prediction using tissue expression profile similarity searches (2008)

We present and validate tissue expression profile similarity searches (TEPSS), a computational approach to identify transcripts that share similar tissue expression profiles to one or more transcripts in a group of interest. We evaluated TEPSS for its ability to discriminate between pairs of transcripts coding for interacting proteins and non-interacting pairs. We found that ordering protein-protein pairs by TEPSS score produces sets significantly enriched in reported pairs of interacting proteins [interacting versus non-interacting pairs, Odds-ratio (OR) = 157.57, 95% confidence interval (CI) (36.81-375.51) at 1% coverage, employing a large dataset of about 50 000 human protein interactions]. When used with multiple transcripts as input, we find that TEPSS can predict non-obvious members of the cytosolic ribosome. We used TEPSS to predict S-nitrosylation (SNO) protein targets from a set of brain proteins that undergo SNO upon exposure to physiological levels of S-nitrosoglutathione in vitro. While some of the top TEPSS predictions have been validated independently, several of the strongest SNO TEPSS predictions await experimental validation. Our data indicate that TEPSS is an effective and flexible approach to functional prediction. Since the approach does not use sequence similarity, we expect that TEPSS will be useful for various gene discovery applications. TEPSS programs and data are distributed at http://icb.med.cornell.edu/crt/tepss/index.xml.
ChemInform Abstract: 4′‐Selenonucleosides as Next‐Generation Nucleosides (2015)

Abstract Review: stereoselective synthesis, conformation analysis, and biological activity of various modified 4′‐selenonucleosides; 20 refs.
FPGA-based Pipeline Architecture to Transform Cartesian Images into Foveal Images by Using a new Foveation Approach (2006)

In vision systems the image processing represents a bottle neck because the big amount of information that should be analyzed. Working with variant spaces over the visual field has been widely proposed as a way to reduce such information. Foveal vision is one of these proposals by providing a way to transform the visual field obtained with conventional cameras into a sampling with high resolution at the center and decreasing over the periphery such as in mammal vision systems. In this paper, an FPGA based architecture to transform conventional images into foveal images is presented. The hardware algorithm has been taken from new proposal to foveate images. Strategies as parallelism and pipeline are exploited to obtain a high performance and thus, with both of them, reduction in the visual field and the transformation in real time of the digital images into foveal images, a vision system can accelerate its performance and reaches real time restrictions
Adaptive sleep mode algorithm in IEEE 802.16e (2007)

Much research has been performed to minimize energy consumption of mobile nodes with high speed mobility. Among them, the IEEE 802.16e has adopted sleep mode to reduce energy consumption. If the base station (BS) has no data to be sent to a mobile node at the instant of ending its current sleep window interval, the mobile node with the sleep mode increases the sleep window interval by double until the window interval reaches to the maximum sleep window interval. After the sleep window interval of the mobile node hits the maximum sleep window interval, the node keeps its sleep window interval as the maximum interval. However, if the node keeps the maximum sleep window interval for a long time, the frame delay is increased and energy is wasted. To shorten the frame delay and deal with the energy of the node effectively, this paper comes up with an algorithm that reduces the next sleep window interval to the medium between the minimum and the maximum sleep window interval after the current sleep window reaches to the maximum sleep window interval. The proposed algorithm decreases the delay by a maximum of 20% and energy consumption by about 5%, compared with the basic algorithm adopted by IEEE 802.16e.
Chromosome 11p15.5 regional imprinting: comparative analysis of KIP2 and H19 in human tissues and Wilms' tumors (1996)

The imprinted H19 gene is frequently inactivated in Wilms' tumors (WTs) either by chromosome 11p15.5 loss of heterozygosity (LOH) or by hypermethylation of the maternal allele and it is possible that there might be coordinate disruption of imprinting of multiple 11p15.5 genes in these tumors. To test this we have characterized total and allele-specific mRNA expression levels and DNA methylation of the 11p15.5 KIP2 gene in normal human tissues, WTs and embryonal rhabdomyosarcoma (RMS). Both KIP2 alleles are expressed but there is a bias with the maternal allele contributing 70-90% of mRNA. Tumors with LOH show moderate to marked reductions in KIP2 mRNA relative to control tissues and residual mRNA expression is from the imprinted paternal allele. Among WTs without LOH most cases with H19 inactivation also have reduced KIP2 expression and most cases with persistent H19 expression have high levels of KIP2 mRNA. In contrast to the extensive hypermethylation of the imprinted H19 allele, both KIP2 alleles are hypomethylated and WTs with biallelic H19 hypermethylation lack comparable hypermethylation of KIP2 DNA. 5-aza-2'-deoxycytidine (aza-C) increases H19 expression in RD RMS cells but does not activate KIP2 expression. These data indicate coordinately reduced expression of two linked paternally imprinted genes in most WTs and also suggest mechanistic differences in the maintenance of imprinting at these two loci.
Efficient monochromatic red-light-emitting PLEDs based on a series of nonconjugated Eu-polymers containing a neutral terpyridyl ligand (2013)

Three novel Eu-polymers containing hole transporting units and light-emitting units in the main chain have been designed and synthesized via radical copolymerization of N-vinylcarbazole and polymerizable Eu(TTA)3vinyl-tpy, where TTA is 2-thenoyltrifluoroacetonate. The chemical structure and composition of the Eu-polymers were characterized by FTIR, UV-vis, 1H NMR, 13C NMR spectroscopy, GPC, ESI-MS, and elemental analysis. The geometry of the polymerizable monomer Eu(TTA)3vinyl-tpy was predicted using the Sparkle/PM6 model and suggested to be in a chemical environment with very low symmetry around the Eu3+ ions (C1), in agreement with the fluorescence spectrum. All Eu-polymers exhibited good solubility, as well as good thermal stability and high glass transition temperatures. The photoluminescence (PL) properties of the copolymers in solution and in the solid state were investigated in detail. Intramolecular energy transfer from the carbazole groups to the europium complexes occurred even in diluted solutions. The efficiency of this process also depended on the composition of the Eu-polymers. In the solid state, emission from the carbazole groups was suppressed and the absorbed excitation energy was transferred effectively to the europium complexes in the Eu-polymers. Most importantly, the EL performances of eight pure red-emission PLEDs based on P1, P2, and P3 as the emitting layer have been studied in detail. Bright electroluminescence with a maximum luminance of 68.2 cd m−2 from the double-layer devices of P1 was demonstrated. Although the EL performance was only the third-best among those of the Eu-chelated polymers reported so far, to the best of our knowledge, this is the first example of electroluminescent devices of Eu-polymers based on tpy as a neutral ligand. These results illustrate the potential application of polymerizable tpy ligands in high performance EL Eu-chelated polymers.
estMax: Tracing Maximal Frequent Itemsets over Online Data Streams (2007)

In general, the number of frequent itemsets in a data set is very large. In order to represent them in more compact notation, closed or maximal frequent itemsets (MFIs) are used. However, the characteristics of a data stream make such a task be more difficult. For this purpose, this paper proposes a method called estMax that can trace the set of MFIs over a data stream. The proposed method maintains the set of frequent itemsets by a prefix tree and extracts all of MFIs without any additional superset/subset checking mechanism. Upon processing a newly generated transaction, its longest matched frequent itemsets are marked in a prefix tree as candidates for MFIs. At the same time, if any subset of these newly marked itemsets has been already marked as a candidate MFI, it is cleared as well. By employing this additional step, it is possible to extract the set of MFIs at any moment. The performance of the proposed method is comparatively analyzed by a series of experiments to identify its various characteristics.
A Pilot Study of Daily Subcutaneous Interleukin-10 in Patients with Chronic Hepatitis C Infection (1999)

The Th1/Th2 cytokine balance is important in persistence of infection and liver injury in chronic hepatitis C. The aim of this study was to administer the anti-inflammatory cytokine, recombinant human interleukin-10 (rHuIL-10), for 28 days in patients with chronic hepatitis C and to assess the safety and measure the effect on alanine aminotransferase (ALT, a marker of hepatic inflammation) levels and serum hepatitis C virus (HCV) RNA values. Three treatment-naive and 13 interferon (IFN) nonresponder patients (total 16 patients) with compensated chronic HCV infection were enrolled in this study. Patients were randomized to receive rHuIL-10 at a dose of 4 or 8 microg/kg/day as a single daily subcutaneous injection for 28 days. ALT values and serum HCV RNA were measured at days 0, 1, 3, 8, 15, 22, and 28 during therapy and at follow-up 2 and 4 weeks after cessation of the 4-week treatment period. ALT values normalized in 9 of 16 patients during therapy and remained normal until the end of treatment in 8 patients. The decreases in ALT values occurred in both the 4 microg and 8 microg dosage groups and were seen in both IFN naive and nonresponder patients. Mean ALT values fell significantly during the study period but usually returned to pretreatment levels by the end of the 4-week follow-up period (p < 0.05). HCV RNA concentrations did not vary significantly during or after therapy. (No patient had either an increase or a decrease in HCV RNA levels of > or =1.5 log during the study.) The drug was well tolerated, with no adverse symptoms noted. Platelet counts fell transiently to 73,000 and 63,000 in 2 patients. No other toxicity was observed, and no patients discontinued therapy. In chronic hepatitis C, short-term therapy with IL-10 was well tolerated and caused transient normalization of ALT values in 50% of patients, which returned to pretreatment levels on cessation of treatment. There were no significant changes observed in serum HCV RNA concentrations during the study. These immunomodulatory effects are similar to those observed with ribavirin monotherapy in chronic hepatitis C. Further study of rHuIL-10 alone or in combination with antiviral agents in chronic hepatitis C is warranted.
Central Blood Pressure, Arterial Waveform Analysis, and Vascular Risk Factors in Glaucoma (2011)

Derived central BP does not reveal significant differences from controls or in glaucoma subgroups, but a reduced pulse pressure was identified. There may be some changes in arterial pulse waveform shape suggesting possible differences in diastolic perfusion. Disc hemorrhages and loss of spontaneous venous pulsation were associated with disease progression.
Correlations between weights and overlap in ensembles of weighted multiplex networks (2014)

Multiplex networks describe a large number of systems ranging from social networks to the brain. These multilayer structure encode information in their structure. This information can be extracted by measuring the correlations present in the multiplex networks structure, such as the overlap of the links in different layers. Many multiplex networks are also weighted, and the weights of the links can be strongly correlated with the structural properties of the multiplex network. For example, in multiplex network formed by the citation and collaboration networks between PRE scientists it was found that the statistical properties of citations to coauthors differ from the one of citations to noncoauthors, i.e., the weights depend on the overlap of the links. Here we present a theoretical framework for modeling multiplex weighted networks with different types of correlations between weights and overlap. To this end, we use the framework of canonical network ensembles, and the recently introduced concept of multilinks, showing that null models of a large variety of network structures can be constructed in this way. In order to provide a concrete example of how this framework apply to real data we consider a multiplex constructed from gene expression data of healthy and cancer tissues.
Reply to Comment on “Can a light beam be considered to be the sum of a completely polarized and a completely unpolarized beam?” (2009)

The authors of the Comment [Opt. Lett. 34, 1001 (2009)] do not mention that no claim was made in the orginal letter that the cross-spectral density matrix of polarized light must be of a factorized form.
Action in pairs (2014)

This article refers to:The yrpAB operon of Yersinia ruckeri encoding two putative U32 peptidases is involved in virulence and induced under microaerobic conditions
A Novel Clonal Selection Algorithm and its Application (2008)

In order to improve some fundamental problems of the clonal selection algorithm (CSA), a novel clonal selection algorithm (NCSA) is proposed. After analyzing the mechanism of the clonal selection and proposing the antibody model, the basic character of the application problem fused into the NCSA based on rearrangements of antibody molecule coding genes. Next, we analyzed synthetically the antibody-antigen affinity and the antibody-antibody affinity. Through contrast experiments between the NCSA and the CSA to solve travelling salesman problem (TSP), it is shown that the NCSA has better performances.
Adaptive optics imaging search for damped Ly$\alpha$ absorbers toward APM 08279+5255 (2005)

We present initial results from an high-resolution imaging search for damped Ly absorbers toward the high-redshift quasar APM 08279+5255 by using the Adaptive Optics system (AO) attached to the Subaru telescope. We detected in total 11 objects within a 23 23 field around the quasar. Among these detected objects, we identified a possible candidate for the galaxy giving rise to the damped Ly absorption at z a bs =2.974 with a criteria of distance from the sight-line toward the quasar and luminosity.
(Polymer/polymer)-like phase behavior in the system tetradecyltrimethylammonium bromide/sodium polyacrylate/water (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT(Polymer/polymer)-like phase behavior in the system tetradecyltrimethylammonium bromide/sodium polyacrylate/waterJ. O. CarnaliCite this: Langmuir 1993, 9, 11, 2933–2941Publication Date (Print):November 1, 1993Publication History Published online1 May 2002Published inissue 1 November 1993https://pubs.acs.org/doi/10.1021/la00035a034https://doi.org/10.1021/la00035a034research-articleACS PublicationsRequest reuse permissionsArticle Views159Altmetric-Citations47LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Serial Analysis of Gene Expression (SAGE) in the Rat Limbal and Central Corneal Epithelium (2006)

The SAGE results extend the database of genes expressed in the rodent cornea and suggest an association between several genes preferentially expressed in the limbal epithelium with cellular proliferation and migration.
Scaled-Out Multilayer Gas−Liquid Microreactor with Integrated Velocimetry Sensors (2005)

We describe the design and flow distribution of a scaled-out gas−liquid silicon-based microreactor that consists of three vertically stacked reaction layers each containing 20 reaction channels. The reaction channels are operated in parallel from single feeds of gas and liquid with a liquid throughput of 80 mL/h. Gas and liquid are introduced to the device through single inlet ports, flow vertically to the reaction layers, and are controllably distributed to the horizontal reaction channels through gas and liquid auxiliary channels that present pressure drops significantly larger than that across the reaction channels. The product mixture flows out of the device through a single outlet port. Flow visualization by pulsed-laser fluorescence imaging reveals that the flow regime is uniform across the top layer. By integrating waveguided optical multiphase flow sensors, slug-flow properties are measured across the reaction channels on the top and middle layers; comparable slug frequencies and slug velocities are obtained.
Reliability of irrigation smears for cervical cancer (1969)

1) Purpose and methods:In recent years, the mass population of screening of uterine cancer by methodof irrigation smears has been carried out in many cities, and considerable results have been obtained.Setting aside positive cases by this method, however, early cancer may be found in negative cases.The re-check-up correctly in the level of mass population of screening has been thought as a difficult problem.The studied about the degree of appearance and quantity of malignant tumor in each cases by method of irrigation smears by patients (a), of smears taken from patients by a gynecologist (doctor) in the some method (b), and the smears in the first examination (c) in 40 cases of Dysplasia and carcinoma in situ by histological examination.2) Results:In stage II and more cases of cervical cancer of uterus, the three cases of (a), (b) and (c) are positive. In the irrigation smears taken by a gynecologist, a little better results were obtained than bpatients, however, there is no great difference bey tween them. Carcinoma in situ and Dysplasia are apt to be missed only by the method of irrigation smears. In early cancer, a number of malignant cases are found by cytologic finding at out-clinic and are easy to be diagnosed, while in the method of irrigation smears, there is a small number of cells and more abnormal cells than stage II cases tend to be found.Comparing the irrigation smears taken correctly by doctors with smears taken by patients, there is no great difference in quantitative relation of malignant tumor.
Characterization of Cellular Elements in Healed Cultured Keratinocyte Autografts Used to Cover Burn Wounds (1990)

Biopsy specimens from unburned skin were obtained from three severely burned patients and placed into tissue culture. After 2 to 3 weeks, the cultured keratinocytes were released from the Petri dishes and transplanted onto the patient's burn wound, which had been completely excised down to muscle fascia, thereby removing all cutaneous elements. Healing cultured autografts were found to become repopulated with Langerhans cells within 3 to 6 weeks. A neodermis rich in fibronectin rapidly formed between the autografts and muscle fascia. However, using monoclonal antibodies to cytokeratins as markers of differentiation, we found that the autograft keratinocytes expressed an abnormal pattern of differentiation that was similar to the differentiation seen in hyperproliferative states such as psoriasis. In contrast, healed split-thickness graft donor sites and reepithelialized interstices of mesh grafts maintained the basal keratinocyte staining pattern of normal skin with the AE-1 monoclonal antibody.
Visible Light-Driven H2 Production over Highly Dispersed Ruthenia on Rutile TiO2 Nanorods (2015)

The immobilization of miniscule quantities of RuO2 (∼0.1%) onto one-dimensional (1D) TiO2 nanorods (NRs) allows H2 evolution from water under visible light irradiation. Rod-like rutile TiO2 structures, exposing preferentially (110) surfaces, are shown to be critical for the deposition of RuO2 to enable photocatalytic activity in the visible region. The superior performance is rationalized on the basis of fundamental experimental studies and theoretical calculations, demonstrating that RuO2(110) grown as 1D nanowires on rutile TiO2(110), which occurs only at extremely low loads of RuO2, leads to the formation of a heterointerface that efficiently adsorbs visible light. The surface defects, band gap narrowing, visible photoresponse, and favorable upward band bending at the heterointerface drastically facilitate the transfer and separation of photogenerated charge carriers.