gebhart/patrepeval huggingface dataset:
The role of cytokinins in responses to water deficit in tobacco plants over‐expressing trans‐zeatin O‐glucosyltransferase gene under 35S or SAG12 promoters (2007)

The impact of water deficit progression on cytokinin (CK), auxin and abscisic acid (ABA) levels was followed in upper, middle and lower leaves and roots of Nicotiana tabacum L. cv. Wisconsin 38 plants [wild type (WT)]. ABA content was strongly increased during drought stress, especially in upper leaves. In plants with a uniformly elevated total CK content, expressing constitutively the trans-zeatin O-glucosyltransferase gene (35S::ZOG1), a delay in the increase of ABA was observed; later on, ABA levels were comparable with those of WT. As drought progressed, the bioactive CK content in leaves gradually decreased, being maintained longer in the upper leaves of all tested genotypes. Under severe stress (11 d dehydration), a large stimulation of cytokinin oxidase/dehydrogenase (CKX) activity was monitored in lower leaves, which correlated well with the decrease in bioactive CK levels. This suggests that a gradient of bioactive CKs in favour of upper leaves is established during drought stress, which might be beneficial for the preferential protection of these leaves. During drought, significant accumulation of CKs occurred in roots, partially because of decreased CKX activity. Simultaneously, auxin increased in roots and lower leaves. This indicates that both CKs and auxin play a role in root response to severe drought, which involves the stimulation of primary root growth and branching inhibition.
Cyclooxygenase‐2 activity is necessary for the angiogenic properties of oncostatin M (1999)

Macrophages play a major role in angiogenesis. We recently reported that oncostatin M (OSM), a cytokine of the interleukin (IL)-6 family secreted by macrophages, has a potent angiogenic activity on human microvascular endothelial cells (HMEC-1), but has no effect on macrovascular cells (human umbilical vein endothelial cells (HUVECs)). In this work, we show that in HMEC-1, OSM (0.5-2.5 ng/ml), leukemia inhibitory factor (LIF) (25 ng/ml), bFGF (25 ng/ml) and IL-1beta (5 ng/ml) induced production of cyclooxygenase (COX)-2. In contrast, in HUVECs, neither OSM nor LIF induced COX-2 mRNA, suggesting that COX-2 might be implicated in the angiogenic activity of OSM. This was confirmed by the inhibiting effect on OSM-induced HMEC-1 proliferation of specific COX-2 inhibitors. In vivo studies confirmed this findings. We conclude that induction of COX-2 by OSM is necessary for its angiogenic activity, but is not sufficient since IL-1beta, which also induces COX-2 in HMEC-1, has only a poor proliferative effect.
Transport-reaction dynamics of particulate organic matter and oxygen in riverbed sediments (2022)

Earth and Space Science Open Archive This is a preprint and has not been peer reviewed. ESSOAr is a venue for early communication or feedback before peer review. Data may be preliminary.Learn more about preprints preprintOpen AccessYou are viewing the latest version by default [v2]Transport-reaction dynamics of particulate organic matter and oxygen in riverbed sedimentsAuthorsEricRodeniDEcenurBulur²Stephanie AnnNapieralski²iDSteven PLoheideMatthewGinder-Vogel²ChristopherZahasky¹EvanArntzen³RubyGhosh⁴See all authors Eric RodeniDCorresponding Author• Submitting AuthorUniversity of Wisconsin-MadisoniDhttps://orcid.org/0000-0002-1555-4343view email addressThe email was not providedcopy email addressEcenur Bulur²University of Wisconsin-Madisonview email addressThe email was not providedcopy email addressStephanie Ann Napieralski²iDUniversity of Wisconsin-MadisoniDhttps://orcid.org/0000-0001-5887-2096view email addressThe email was not providedcopy email addressSteven P LoheideUniversity of Wisconsin-Madisonview email addressThe email was not providedcopy email addressMatthew Ginder-Vogel²University of Wisconsin-Madisonview email addressThe email was not providedcopy email addressChristopher Zahasky¹University of Wisconsin-Madisonview email addressThe email was not providedcopy email addressEvan Arntzen³Pacific Northwest National Laboratoryview email addressThe email was not providedcopy email addressRuby Ghosh⁴OptiO2, LLCview email addressThe email was not providedcopy email address
Diagnostic Fine-Needle Aspiration Biopsy for Iris Melanoma (2015)

Although indicated only in minority of cases, it is important to consider FNAB for the diagnosis and management of iris lesions.
Profilin Is Required for Optimal Actin-Dependent Transcription of Respiratory Syncytial Virus Genome RNA (2000)

Transcription of human respiratory syncytial virus (RSV) genome RNA exhibited an obligatory need for the host cytoskeletal protein actin. Optimal transcription, however, required the participation of another cellular protein that was characterized as profilin by a number of criteria. The amino acid sequence of the protein, purified on the basis of its transcription-optimizing activity in vitro, exactly matched that of profilin. RSV transcription was inhibited 60 to 80% by antiprofilin antibody or poly-L-proline, molecules that specifically bind profilin. Native profilin, purified from extracts of lung epithelial cells by affinity binding to a poly-L-proline matrix, stimulated the actin-saturated RSV transcription by 2.5- to 3-fold. Recombinant profilin, expressed in bacteria, stimulated viral transcription as effectively as the native protein and was also inhibited by poly-L-proline. Profilin alone, in the absence of actin, did not activate viral transcription. It is estimated that at optimal levels of transcription, every molecule of viral genomic RNA associates with approximately the following number of protein molecules: 30 molecules of L, 120 molecules of phosphoprotein P, and 60 molecules each of actin and profilin. Together, these results demonstrated for the first time a cardinal role for profilin, an actin-modulatory protein, in the transcription of a paramyxovirus RNA genome.
Characterization of 26 Staphylococcus warneri isolates from orthopedic infections (2010)

Staphylococcus warneri is a coagulase negative Staphylococcus (CNS) commonly present in the flora of human epithelia and mucosal membranes. Over the last two decades, similarly to other CNS species, S. warneri has been reported as a new emerging pathogen, capable of causing serious infections usually in association with the presence of implant materials, but, at times, even in the absence of a foreign body and in patients considered immunocompetent. At present, there is still a lack of scientific data on the pathogenesis and epidemiology of this species. The present study investigated a collection of 26 clinical isolates derived from orthopedic infections, some associated with implant materials and others not. Automated ribotyping showed the existence of 5 distinct ribogroups. Except for the least numerous ribogroup consisting of a single isolate, all other ribogroups included at least one strain obtained from an infection not associated with implant materials, suggesting that putative virulence factors necessary for infections even in the absence of a foreign body could be transversal to most ribogroup categories. Orthopedic infections were found to involve S. warneri strains with low antibiotic resistance potential, differing in this respect from the strains isolated at neonatal intensive care units, where this species has been described to figure among the principal causative agents and exhibit an alarming profile of antibiotic resistance.
Cigarette Smoke Formation Studies: V. The Effects of the Cigarette Periphery on Mainstream Smoke Formation (1977)

Abstract The effects of the cigarette periphery on smoke formation have been experimentally studied. A series of cigarettes was prepared with carbon-14 labelled materials placed in different radial positions within the rods. These cigarettes were smoked and the distribution of the radioactivities into total smoke was measured. These data lead to the following conclusions: [1 ] The periphery plays a large contributing role (though not the sole role) in the formation of a) the mainstream particulate phase, b) sidestream particulate phase (derived from non-distillable/non-sublimable materials), and c) mainstream gas phase (derived from non-distillable/non-sublimable materials) ; [2] The central portion of the cigarette rod plays a large contributing role in a) sidestream gas phase and b) sidestream particulate phase (derived from distillable/sublimable compounds); and [ 3 ] The mainstream gas phase yields from the distillable/sublimable compounds are due in large part to the pyrolysis/combustion products formed during the static burn period. These products are carried into mainstream smoke by the incoming air at the beginning of the puff and by diffusion due to the pressure gradient existing in the cigarette during static burn. These experiments have demonstrated the significant effects that the central portion of the cigarette rod has on sidestream smoke formation and, conversely, the effects of the periphery on mainstream smoke.
Introducing a new Element - Fluorine -Into the Liposomal Membrane (1995)

AbstractAmphiphiles with fluorinated hydrophobic tails constitute new, distinctively different components for membranes, liposomes, tubules and other self-aggregated supramolecular systems. Fluorinated liposomes (F-liposomes) can also be obtained from combinations of standard phospholipids with mixed fluorocarbon-hydrocarbon amphiphiles. The fluorinated moieties are considerably more hydrophobic than their hydrocarbon counterparts; they have also a larger cross section, are more rigid, and are lipophobic as well. As a result, fluorinated amphiphiles show enhanced propensity to self-assemble, lead to increased membrane ordering and stability, and their stacking creates a teflon-like repellent film within the liposomal membrane, which can significantly increase drug encapsulation stability. The fluorinated chains also impact on behavior in biological media and particle recognition, as exemplified by reduced hemolytic and detergent activity, prolonged intravascular persistence, or slower enzymatic hydrolysis of phospholipids.
Programmable correlation using parametric interactions in acoustic surface waves (1972)

Real-time correlation of 31 chip binary p.s.k. waveforms has been obtained using nonlinear interactions of acoustic surface waves, with a signal bandwidth of 8 MHz. A dynamic range of 20 dB was obtained. Calculations indicate that a dynamic range of 50 dB should be obtainable quite readily, making the device attractive for adaptive signal processing.
ChemInform Abstract: Nonlinear Optical Materials for Integrated Optics: Telecommunications and Sensors (1993)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
6.1: Roll‐to‐Roll Manufacturing Considerations for Flexible, Cholesteric Liquid Crystal (ChLC) Display Media (2005)

Abstract Roll‐to‐roll methods and equipment to manufacture a bistable flexible electronic display have been developed. Displays produced with these processes are low‐cost, thin, flexible, passively driven, and retain an image without an applied electric field. Using continuous coating techniques and equipment, an aqueous cholesteric liquid‐crystal dispersion and a dark layer are deposited onto laser‐etched patterned transparent conductors on a polymeric web. Second conductors are printed with a UV‐curable polymer thick film ink over the active display layers, followed by slitting and chopping to complete the manufacture of display media in a full roll‐to‐roll process. Simple seven‐segment and matrix displays can be generated using these techniques. This paper will focus on the manufacturing considerations for producing matrix display media.
Multi-Engine Machine Translation by Recursive Sentence Decomposition (2006)

In this paper, we present a novel approach to combine the outputs of multiple MT engines into a consensus translation. In contrast to previous Multi-Engine Machine&#13;\nTranslation (MEMT) techniques, we do not rely on word alignments of output hypotheses, but prepare the input sentence for multi-engine processing. We do this by using a recursive decomposition algorithm that produces simple chunks as input to the MT engines. A consensus translation&#13;\nis produced by combining the best chunk translations, selected through majority voting, a trigram language model&#13;\nscore and a confidence score assigned to each MT engine. We report statistically significant relative improvements&#13;\nof up to 9% BLEU score in experiments (English→Spanish) carried out on an 800-sentence test set extracted from the Penn-II Treebank.
Discovery of Potent and Selective RSK Inhibitors as Biological Probes (2015)

While the p90 ribosomal S6 kinase (RSK) family has been implicated in multiple tumor cell functions, the full understanding of this kinase family has been restricted by the lack of highly selective inhibitors. A bis-phenol pyrazole was identified from high-throughput screening as an inhibitor of the N-terminal kinase of RSK2. Structure-based drug design using crystallography, conformational analysis, and scaffold morphing resulted in highly optimized difluorophenol pyridine inhibitors of the RSK kinase family as demonstrated cellularly by the inhibition of YB1 phosphorylation. These compounds provide for the first time in vitro tools with an improved selectivity and potency profile to examine the importance of RSK signaling in cancer cells and to fully evaluate RSK as a therapeutic target.
Validation of expressive XML keys with XML schema and XQuery (2015)

The eXtensible Markup Language (XML) is the defacto industry standard for exchanging data on the Web and elsewhere. While the relational model of data enjoys a well-accepted definition of a key, several competing notions of keys exist in XML. These have complementary properties and therefore serve different applications domains. In a nutshell, XML keys allow us to capture important domain semantics in XML documents and thereby advance data processing in most applications. In this paper we propose how to validate XML documents against an expressive class of XML keys using XML Schema and XQuery, respectively. It is somewhat surprising how simple it is to express sophisticated notions of XML keys in these off-the-shelf tools. Experiments show that our simple validation technique works well for real-world data of reasonable size. For large-scale data, however, dedicated tools must be developed.
Aktualni razvoj u tehnologiji oblikovanja kompozitnih materijala (2015)

This paper gives an overview of composites materials manufacturing,processing methods and their properties. The basic technologies of deformation like rolling, extrusion, forging and drawing are listed. Described are the technologies of rolling composites sheets for bearings in
which the main components are aluminium alloy and steel as the core materiel. The technologies of extrusion from hybrid sheets with bimetal core are described. In the end the technologies of drawing thin wires from composites materials are shown.
SIGNAL TRANSDUCTION BY GALANIN RECEPTOR (1997)

Conference Article| August 01 1997 SIGNAL TRANSDUCTION BY GALANIN RECEPTOR Ülo Langel Ülo Langel 1Department of Neurochemistry and Neurotoxicology, Arrheniuslaboratories, Stockholm University, S-106 91 Stockholm, Sweden Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1997) 25 (3): 429S. https://doi.org/10.1042/bst025429s Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Cite Icon Cite Get Permissions Citation Ülo Langel; SIGNAL TRANSDUCTION BY GALANIN RECEPTOR. Biochem Soc Trans 1 August 1997; 25 (3): 429S. doi: https://doi.org/10.1042/bst025429s Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu nav search search input Search input auto suggest search filter All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1997 Biochemical Society1997 Article PDF first page preview Close Modal You do not currently have access to this content.
Observing Second‐Order Nonlinear Optical Properties by Symmetry Breaking in Centrosymmetric Furan‐Containing Oligoaryl Cyclophandienes (2009)

Centrosymmetric furan-containing cyclophandienes 3 and 4, synthesized by our furan annulation protocol, have been shown to exhibit extraordinarily large Stokes shifts and second-order nonlinear optical beta values. The beta values for 3 and 4 measured at 1.32 mum are 208 and 530x10(-30) esu, respectively. The beta values of 3 and 4 are similar to those of respective cyclophenes 1 a and 7 in which strong hyperpoarizable interactions between two twisted pi-systems (oligoaryl and bridging double bond) might take place. Symmetry breaking due to the resonance contribution (cf. 2) and the unique structural features of 3 and 4 has been used to account for this unusual photophysical behavior.
Baroreceptor Modulation of the Cardiovascular System, Pain, Consciousness, and Cognition (2021)

Baroreceptors are mechanosensitive elements of the peripheral nervous system that maintain cardiovascular homeostasis by coordinating the responses to external and internal environmental stressors. While it is well known that carotid and cardiopulmonary baroreceptors modulate sympathetic vasomotor and parasympathetic cardiac neural autonomic drive, to avoid excessive fluctuations in vascular tone and maintain intravascular volume, there is increasing recognition that baroreceptors also modulate a wide range of non-cardiovascular physiological responses via projections from the nucleus of the solitary tract to regions of the central nervous system, including the spinal cord. These projections regulate pain perception, sleep, consciousness, and cognition. In this article, we summarize the physiology of baroreceptor pathways and responses to baroreceptor activation with an emphasis on the mechanisms influencing cardiovascular function, pain perception, consciousness, and cognition. Understanding baroreceptor-mediated effects on cardiac and extra-cardiac autonomic activities will further our understanding of the pathophysiology of multiple common clinical conditions, such as chronic pain, disorders of consciousness (e.g., abnormalities in sleep-wake), and cognitive impairment, which may result in the identification and implementation of novel treatment modalities. © 2021 American Physiological Society. Compr Physiol 11:1373-1423, 2021.
Signal sorting in ESM systems (1985)

As radar signal environments become denser and radar signals become more complex, the task of an ESM operator becomes more difficult. In environments where the numbers of radars may be large and the number of pulses transmitted by a radar may be small, the operator becomes the dominating factor in the efficiency of an ESM system. The paper discusses the problem of developing automatic sorting of radar environments, in order to assist, and eventually replace, the ESM equipment operator. The paper separates the signal sorting problem into two subproblems of describing the radar environment in a pulse-train sorter and monitoring changes in the perceived environment in a new-signal detector. Emphasis is placed on the need to use all available pulse parameter measurement data in order to achieve the highest possible confidence in the descriptions of the emitters which the signal sorter provides.
Resting-State Functional Connectivity by Independent Component Analysis-Based Markers Corresponds to Areas of Initial Seizure Propagation Established by Prior Modalities from the Hypothalamus (2016)

Non-invasive connectivity measures correspond to areas of initial ictal propagation and differentiate such areas from secondary ictal propagation, which may aid in ictal focus surgical disconnection planning and support the use of this newer modality for adjunctive information in epilepsy surgery evaluation.
Coherent electro-optical detection of THz-wave generated from synchronously pumped picosecond THz parametric oscillator (2012)

Terahertz (THz) radiation via parametric down-conversion of optical pulses in a nonlinear optical crystal is an attractive way to develop frequency tunable THz-wave sources. Therefore, we have focused on developing low-laser-powerpumped THz-wave parametric sources and then successfully demonstrated a synchronously-pumped picosecond THz parametric oscillator (TPO) in pump-enhanced idler-resonant cavity with a bulk 5 mol% MgO-doped lithium niobate (MgO:LN) crystal. In this paper, toward coherent electro-optical (EO) detection of THz waves generated from our synchronously pumped picosecond TPO, we reported time-domain measurements of the THz electric fields using a bowtie- shaped low-temperature grown gallium arsenide (LT-GaAs) photoconductive (PC) antenna as a THz detector. As a result, we obtained temporal waveforms of the THz electric pulses, for the different number of Si-prism couplers, and then found that the radiated THz waves separated multiple unanticipated pulses by use of the arrayed-prism coupling technique. Also, we compared the time-domain system with a Fourier transform Michelson interferometer using a highresistance silicon (Si) beam splitter, from the some viewpoints. The present results reveal great prospects for the realization of THz spectroscopy and imaging applications using our THz-wave source.
Through a graph, darkly (2012)

Social Media Data abounds. Industry plays fast and loose with our privacy, for profit. How can researchers lead the way to a more ethical, respectful world? In this keynote, I will discuss the problems and try to lead a discussion towards potential solutions.
Incorporating quality aspects in sensor data streams (2007)

Sensors are increasingly embedded into physical products in order to capture data about their conditions and usage for decision making in business applications. However, a major issue for such applications is the limited quality of the captured data due to inherently restricted precision and performance of the sensors. Moreover, the data quality is further decreased by data processing to meet resource constraints in streaming environments and ultimately influences business decisions. The issue of how to efficiently provide applications with information about data quality (DQ) is still an open research problem.
Proteoglycan 4 (PRG4) synthesis and immunolocalization in bovine meniscus (2005)

Proteoglycan 4 (PRG4) is synthesized and secreted into the synovial fluid by articular chondrocytes and synovial cells, lining the cavity of joints. A thin layer of PRG4 is also present at the articular surface, where it appears to be involved in boundary lubrication. This study investigated if PRG4 is also synthesized and secreted by the cells within meniscus, and if PRG4 is also present in, and at the surface of, meniscus. PRG4 was visualized in sections of bovine calf menisci by immunohistochemistry. PRG4 was detected in two regions: (1) at the femoral and tibial surfaces of the meniscus, and within cells below these surfaces; and (2) within and near cells along the radial tie fibers and circumferential fibers. From meniscus tissue harvested from these surfaces, PRG4 was extracted with 4M GuHCl and quantified by ELISA. There was 0.20 +/- 0.01 and 0.25 +/- 0.04 microg PRG4/cm(2) area of lateral and medial meniscus surface, respectively. ELISA analysis of spent medium from other samples of meniscus surface tissue incubated in medium supplemented with serum and ascorbate showed that 8.1 +/- 1.1 microg PRG4/cm(2) area of meniscus surface was secreted over six days. These results demonstrate that PRG4 is synthesized and secreted by certain cell populations in the meniscus, and that PRG4 is present in the meniscus at surfaces and also internal fibers where it may contribute to boundary lubrication.