gebhart/patrepeval huggingface dataset:
Malnutrition Prevalence Measurement and Nutritional Interventions in Internal Medical Departments of Turkish Hospitals: Results of the LPZ Study (2021)

Objective: The Landelijke Prevalentiemeting Zorgkwaliteit (LPZ), or National Care Indicators Prevalence, study is an annual international multicenter cross-sectional prevalence measurement of care problems on the institution, department, and patient level across Europe. The aim of this study was to measure the prevalence of malnutrition (MN) and examine nutritional interventions in internal medical departments of Turkish hospitals. Methods: A multicenter, cross-sectional study was performed using a standardized and tested questionnaire. Data were collected from adult patients (18 years and over) who were hospitalized in internal medical departments of the hospitals. The cross-sectional study was done in 12 different centers from six big cities in the country in every November of three consecutive years (2017–2019). Results: A total of 1,764 patients (60.9% men, 39.1% women; mean age, 62.6±0.4 years; range, 18–99 years) from 12 centers were enrolled in the study. The main diagnoses were cardiovascular disease (35.8%), diabetes (29.3%), cancer (20.2%), respiratory diseases (20.0%), infectious diseases (18.7%), gastrointestinal diseases (18.5%), endocrine diseases (17.3%), neurological diseases (15%; dementia, 6%), and hematological diseases (9.3%). Mean weight and body mass index of the patients were 71.9±16.5 kg (range, 30–153 kg) and 27.0±5.1 kg/m2 (range, 10.6–51.3 kg/m2). MN risk prevalence was 44.2%, according to the malnutrition universal screening test (MUST), and 46.5% in elderly patients. Of the patients, 43.4% indicated unintentional weight loss in the last 6 months. Nutritional interventions to treat MN were referral to a dietitian (57.2%), oral nutrition supplements (40.7%), energy/protein–enriched diet (38%), energy/protein–enriched snacks (18.1%), parenteral nutrition (16.7%), support at mealtimes (15.8%), and tube enteral feeding (10.4%). No interventions were given to 5.4% of patients. Regular audits were made to ensure compliance with the protocol/guidelines in 88.5% of patients, and 68.5% of patients were discussed with multidisciplinary teams at the hospitals. Conclusion: MN is highly prevalent the in internal medical departments of our hospitals. Although MN awareness is increasing, different interventions are in use according to national and international protocols/guidelines, and the number of active multidisciplinary teams is increasing. MN is still a big problem that needs further national plans.
Endovascular Low-Dose Irradiation Inhibits Neointima Formation After Coronary Artery Balloon Injury in Swine (1995)

Low-dose intracoronary irradiation delivered to the site of coronary arterial overstretch balloon injury in pigs inhibited subsequent intimal thickening (hyperplasia). A dose-response relationship was demonstrated, and delay of treatment for 48 hours appeared to augment the inhibitory effect. Six months of follow-up without fibrosis or arteriosclerosis demonstrated the durability of the beneficial effect in the treated group. These data suggest that intracoronary irradiation therapy may aid in preventing clinical restenosis.
Caractérisation de matériaux composites à gradient fonctionnel bio-inspiré par ondes élastiques : mesures ultrasonores et modélisation mécanique (2022)

International audience
Mechanisms of cartilage destruction and novel nonsurgical therapeutic strategies to retard cartilage injury in rheumatoid arthritis. (1997)

Although there are excellent rationales for the use of biologic agents, no published novel therapeutic strategy in patients with early or late rheumatoid arthritis has thus far been proven in controlled clinical studies to prevent or retard cartilage destruction. Although T-cell-specific therapies in chronic rheumatoid arthritis have some success, the percentage of patients responding and the degree of clinical improvement are disappointing, and cartilage injury can neither be prevented nor retarded. Similarly, attempts to interrupt the cytokine loops and inhibit adhesion molecules are only modestly successful. The alternative approach of solely controlling the effector side by direct or indirect metalloproteinase inhibition seems attractive because it would circumvent the cytokine networks while theoretically still preventing the final consequences of inflammation on cartilage. One therapeutic strategy that inhibits metalloproteinses-tetracyclines or chemically transformed tetracyclines-cannot be considered a breakthrough with respect to either reduction of disease activity or prevention or retardation of cartilage injury in rheumatoid arthritis. It is likely that combination therapy will be further developed in the future. The most promising agents today, such as the anti-tumor necrosis factor-alpha antibodies, must be combined with other current strategies as well as with newly developed disease-specific biologic agents. To affect multiple sites in the underlying inflammatory process and to target the delivery of the agents could be one of the goals. The efficacy and effectiveness of any new strategy depends on its ability to alter the function of the aggressive and transformed synovial fibroblasts within the pannus and to protect the articular chondrocytes and early cartilage injury.
miR-187-3p inhibits the metastasis and epithelial–mesenchymal transition of hepatocellular carcinoma by targeting S100A4 (2016)

miR-187-3p, a novel cancer-related microRNA, was previously reported to play promoting or suppressive roles in different malignancies. However, the expression level, biological function, and underlying mechanisms of miR-187-3p in hepatocellular carcinoma (HCC) remain unknown. This study demonstrated that miR-187-3p was significantly down-regulated in HCC tissues and cell lines, and was associated with advanced TNM stage and metastasis in HCC. Functional studies confirmed that miR-187-3p could inhibit the metastasis of HCC both in vitro and in vivo. Moreover, we proved that miR-187-3p could prevent the epithelial-mesenchymal transition (EMT) of HCC cells. Mechanically, S100A4 was a direct downstream target of miR-187-3p, and mediated the functional influence of miR-187-3p in HCC. Furthermore, miR-187-3p and S100A4 expression was evidently correlated with adverse clinical features and poor prognosis of HCC. Lastly, we showed that hypoxia was responsible for the significantly decreased level of miR-187-3p in HCC, and miR-187-3p was involved in the promoting effects of hypoxia on the metastasis and EMT of HCC cells. Taken together, miR-187-3p inhibits the metastasis and EMT in HCC by targeting S100A4. miR-187-3p can serve as a prognostic indicator and a promising therapeutic target for HCC patients.
The Impacts of Timing Constraints on Virtual Channels Multiplexing in Interconnect Networks* (2006)

Interconnect networks employing wormhole-switching play a critical role in shared memory multiprocessor systems-on-chip (MPSoC) designs, multicomputer systems and system area networks. Virtual channels greatly improve the performance of wormhole-switched networks because they reduce blocking by acting as "bypass" lanes for non-blocked messages. Capturing the effects of virtual channel multiplexing has always been a crucial issue for any analytical model proposed for wormhole-switched networks. Dally has developed a model to investigate the behaviour of this multiplexing which have been widely employed in the subsequent analytical models of most routing algorithms suggested in the literature. It is indispensable to modify Daily's model in order to evaluate the performance of channel multiplexing in more general networks where restrictions such as timing constraints of input arrivals and finite buffer size of queues are common. In this paper we consider timing constraints of input arrivals to investigate the virtual channel multiplexing problem inherent in most current networks. The analysis that we propose is completely general and therefore can be used with any interconnect networks employing virtual channels. The validity of the proposed equations has been verified through simulation experiments under different working conditions
Co-ordinated regulation of translation following DNA damage (2009)

Comment on: Powley IR, Kondrashov A, Young LA, Dobbyn HC, Hill K, Cannell IG, et al. Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes. Genes Dev 2009; 15:1207-20.
Recent experiences in using TOUGH2 for geothermal modelling (2012)

The geothermal modelling group in Engineering Science (University of Auckland) is involved with several geothermal R&D projects. On the development side we are running models of Ohaaki, Wairakei, Ngawha, Reporoa, Wayang Windu and Lihir. Our experiences in these projects have led on to several parallel research projects. Our model of Wairakei-Tauhara is so large that it also contains the Rotokawa system and the edge of the Ngatamriki system. Trying to understand the large-scale convection process at Wairakei-Tauhara has led on to studies of more generic convection studies and studies of larger areas of the TVZ. It has also led on to deeper models which require equations of state that can handle high pressures and temperatures. We have developed one for pure water but now wish to extend it to include CO2 and NaCl. With larger and larger models the computational demand increases quickly and we are now routinely using TOUGH_MP, the parallel version of TOUGH2. Also with large complex models dealing with input and output is a major task and we have developed a suite of PYTHON scripts (called pyTOUGH) for carrying out several model management tasks. One of the biggest challenges in geothermal modelling is model calibration and we have carried out studies using inverse modelling with iTOUGH and PEST and also Markov Chain Monte Carlo methods (MCMC). We are also carrying out miscellaneous studies of resewrvoir physics several of which involve fluid/rock interaction, for example the effects of cold water injection on permeability and subsidence in geothermal fields.
A Scalable Synthesis of l-Leucine-N-carboxyanhydride (2005)

Due to its relevance in the synthesis of well-defined oligopeptides, the l-leucine-N-carboxyanhydride (leucine-NCA) synthesis was selected for fine chemical scale-up with a scope on application on larger scales. The heterogeneous gas−solid−liquid nature of the leucine-NCA synthesis implied a mass transfer limited reaction rate towards phosgenation and was investigated on bench scale. Upon scale increase, the liquid−gas mass transport of HCl is drastically reduced, retarding the reaction and consequently rendering the process unsuitable for scale-up. Addition of an HCl scavenger such as (+)-limonene prevented side reactions thus allowing a cost reduction, a considerably faster reaction, and minimization of the amount of phosgene source used. The modified leucine-NCA synthesis has successfully been made scalable, maintaining high product purity on a 1.0 dm3 scale.
An Improved Gesture Segmentation Method for Gesture Recognition Based on CNN and YCbCr (2021)

With the continuous improvement of people’s requirements for interactive experience, gesture recognition is widely used as a basic human-computer interaction. However, due to the environment, light source, cover, and other factors, the diversity and complexity of gestures have a great impact on gesture recognition. In order to enhance the features of gesture recognition, firstly, the hand skin color is filtered through YCbCr color space to separate the gesture region to be recognized, and the Gaussian filter is used to process the noise of gesture edge; secondly, the morphological gray open operation is used to process the gesture data, the watershed algorithm based on marker is used to segment the gesture contour, and the eight-connected filling algorithm is used to enhance the gesture features; finally, the convolution neural network is used to recognize the gesture data set with fast convergence speed. The experimental results show that the proposed method can recognize all kinds of gestures quickly and accurately with an average recognition success rate of 96.46% and does not significantly increase the recognition time.
Lights oils from hydrocarbonization of coal (1971)

Yields and characteristics of light oil in the gasoline boiling range were determined for six coals ranging in rank from low volatile bituminous to lignite. The coals were hydrocarbonized at low temperature in a fixed-bed carbonizer, and the vapors produced were catalytically hydrorefined at hydrogen pressures of 300, 600, and 900 psig. Light oil produced in this manner was olefin free and rich in benzene, toluene, and xylene (BTX), and would be suitable for blending in the production of nonleaded gasoline. A maximum BTX yield of 76 lb was obtained from a ton of dry, ash-free high-volatile bituminous coal. Linear polynuclear aromatic compounds were found in the tar in sufficient amounts to make this a potential source of additional benzene, toluene, and xylene.
Weight loss over time and survival: a landmark analysis of 1000+ prospectively treated and monitored lung cancer patients (2020)

Weight should be integrated into cancer cachexia trials because of its ease of frequent measurement and sustained prognostic association.
Management Information Base of Intermediate System to Intermediate System Multiple Instance (2010)

This draft defines a portion of the Management Information Base (MIB)
for use with network management protocols in the Internet community.
Specifically, this draft describes a MIB for the IS-IS Routing
protocol that allows a single router to share one or more links among
multiple IS-IS routing protocol instances
Path following controller for autonomous vehicles (2019)

In recent years vehicles with high level of automation are becoming more popular which is expected to continue in the future. Advanced driving assistance systems are increasingly taking control of the vehicle, starting with the support of the driving task. Automated or highly automated vehicles are expected to follow a planned road safely. In this paper, the authors aim to improve the accuracy of path following by developing a new control strategy. The controller includes both pure pursuit and Stanley methods, the operation of the controller is based on the geometry of the vehicle and the path; the key is the proper weighting between two controllers. The performance of the combined path following controller was measured on a demonstration vehicle.
Synthesis of Mesoporous Silica from Sodium Silica Solutions and a Poly(ethylene oxide)-Based Surfactant (1999)

Preparation of mesoporous silica by the neutral route has advantages compared with that by electrostatic routes, however, until now the starting materials were alkoxysilanes-rather expensive silica sources. A synthesis is presented that starts from sodium silicate solutions, as an inexpensive inorganic silicon source, and a poly(ethylene oxide)-based neutral surfactant. The communication focuses on the influence of the polycondensation conditions, e.g., pH, synthesis temperature, aging time, and surfactant-to-silica molar ratio, on the stability and pore size of the materials.
The Limits of Experiment, 1917–1927 (1991)

The outside world could make little sense of the October Revolution in its early years. Even the spelling of 'Bolsheviks' gave trouble. The meteoric passage of Lenin's party from the shadows of pre-1917 clandestinity to power and renown in Petrograd baffled and, except among groups of the political far left, terrified those seeking to understand it. Wartime disruption of communications impeded analysis. Another problem was that the Bolsheviks said they were socialists and yet, unmistakably, they differed basically from most socialists in countries to the West. Fantastic stories gained currency. A vogue grew up for the traveller's tale of depravity and torture. The Bolsheviks supposedly had descended upon Russia like a new Mongol horde; but, unlike Genghis Khan, they were held to be pursuing a meticulously articulated grand plan. Alas for Mother Russia! The Bolshevik Central Committee was deemed to have pre-ordained for her a nightmare of social engineering. The assumption was rife that Lenin and his associates had already determined exactly how and when to realise their objective. Russia was to be the first experimental grist in the Bolshevik mill. The rest of the globe would shortly follow.
ChemInform Abstract: Fused Imidazopyrazoles: Synthetic Strategies and Medicinal Applications (2015)

Abstract Review: 63 refs.
Association of Cataract Surgery With Risk of Diabetic Retinopathy Among Asian Participants in the Singapore Epidemiology of Eye Diseases Study (2020)

The findings of this population-based cohort study suggest that prior cataract surgery was associated with a higher risk of developing DR among individuals with diabetes. Further validation is warranted to confirm this association.
The functional reserve of collaterals supplying long-term chronic total coronary occlusions in patients without prior myocardial infarction (2006)

A limited increase in collateral flow and the high prevalence of coronary steal during stress underscore the functional limitation of collaterals in CTOs without prior Q-wave MI. Even presumably 'well-collateralized' CTOs may benefit from a revascularization.
A Compact DC I-V Model for ReRAM (2020)

In this work, a simple DC I-V model is developed for ReRAM devices. Different stages of a generic ReRAM operation such as forming of low resistance state (LRS), SET in forward and reverse applied-bias and RESET to high resistance state (HRS) are explicitly modeled with key independent parameters such as SET/RESET voltage and HRS/LRS resistance values. This approach of using key parameters as SPICE model input enables the device and circuit designers to come up with design guidelines for the final T-1R specifications from the READ/WRITE margin analysis. Based on Monte-Carlo simulations, the maximum allowable process variations can be estimated quickly and accurately, thus providing a standard design methodology for 1T-1R architectures.
User centered design (1996)

article Free Access Share on User centered design: quality or quackery? Author: John Karat IBM T.J. Watson Research Center IBM T.J. Watson Research CenterView Profile Authors Info & Claims InteractionsVolume 3Issue 4July/Aug. 1996 pp 18–20https://doi.org/10.1145/234813.234814Online:01 July 1996Publication History 9citation899DownloadsMetricsTotal Citations9Total Downloads899Last 12 Months48Last 6 weeks8 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
State of the practice on software release planning (2017)

In the recent years, the academic literature has reported many different proposals addressing the problem of Software Release Planning (SRP). However, nearly none of these results has been transferred to commercial tools for project management, although many of these tools claim to support some SRP tasks. In this paper, we present a study on 119 project management tools to know to which
extent they use advanced AI-assisted algorithms/techniques to support SRP tasks.
Biotic and Abiotic Anaerobic Transformations of Trichloroethene and cis-1,2-Dichloroethene in Fractured Sandstone (2008)

A fractured sandstone aquifer at an industrial site in southern California is contaminated with trichloroethene (TCE) and cis-1,2-dichloroethene (cis-DCE) to depths in excess of 244 m. Field monitoring data suggest that TCE is undergoing reduction to cis-DCE and that additional attenuation is occurring. However, vinyl chloride (VC) and ethene have not been detected in significant amounts, so that if transformation is occurring, a process other than reductive dechlorination must be responsible. The objective of this study was to evaluate the occurrence of biotic and abiotic transformation processes at this site for TCE, cis-DCE, and VC. Anaerobic microcosms were constructed with site groundwater and sandstone core samples. 14C-labeled compounds were used to detect transformation products (e.g., CO2 and soluble products) that are not readily identifiable by headspace analysis. The microcosms confirmed the occurrence of biotic reduction of TCE to cis-DCE, driven by electron donor in the groundwater and/or sandstone. VC and ethene were not detected. Following incubation periods up to 22 months, the distribution of 14C indicated statistically significant transformation of [14C]TCE and [14C]cis-DCE in live microcosms, to as high as 10% 14CO2 from TCE and 20% 14CO2 from cis-DCE. In autoclaved microcosms, significant transformation of [14C]TCE and [14C]cis-DCE also occurred; although some 14CO2 accumulated, the predominant 14C product was soluble and could not be stripped by N2 from an acidic solution (referred to as nonstrippable residue, or NSR). Characterization of the NSR by high-performance liquid and ion chromatography identified glycolate, acetate, and formate as significant components. These results suggest that a combination of abiotic and biotic transformation processes is responsible for attenuation of TCE and cis-DCE in the fractured sandstone aquifer. Tracking the distribution of 14C during the microcosm study was essential for observing these phenomena.
Bi-2212 round wire development for high field applications (2014)

Oxford Superconducting Technology (OST) has been continuously improving Bi-2212 round wire performance because of its potential for application in high-field magnets (> 25 T). We focused on Bi-2212 wire configuration design, filament densification and reducing carbon and hydrogen contamination to improve the engineering critical current density (JE). Several wire configurations have been developed to meet different wire diameter and operating current requirements. The swaging, cold isostatic pressing (CIP) and over-pressure heat treatment processes have been demonstrated to effectively increase Bi-2212 filament mass density in the final wire and result in high performance over long length. The JE values exceeding 550 A/mm2 at 4.2 K, 15 T have been achieved on the CIPed 1 m long sample using a 10 bar over-pressure (OP) heat treatment. The twisted Bi-2212 wire significantly reduced ac loss without the critical current degradation.
<title>Preparation Of Epitaxial Thin Film Lead Salt Infrared Detectors</title> (1981)

Photovoltaic diode infrared detectors are fabricated by depositing metallic lead on p-type lead-salt epitaxial films. The films are grown from the vapor phase by a modified hot wall technique, under pressures on the order of 5 x 10-6 Torr. The carrier concentration of these films is typically in the low 1017 cm-3, and the mobility is a few thousands cm /V sec at 77 K. The lead salts for the growth process are prepared by heating the elemental materials in sealed quartz ampoules. The substrates used for these films are usually BaF2 with a {111} cleavage plane. The formation of Schottky barrier junctions on lead salt films has been reported to be dependent on the chemistry of the interface, such as the presence of oxygen. Furthermore it was found recently that the presence of chlorine vastly improved the I-V characteristics of diode junctions. A simple process for introducing chlorine to the semiconductor surface prior to lead deposition was developed. This process has proved to yield good quality diodes with consistency.