gebhart/patrepeval huggingface dataset:
A digital approach to an FM exciter (1992)

A digital approach to an FM exciter is presented that provides several advantages over previous analog techniques. This approach, called direct digital frequency modulation (DDFM), is centered around a direct digital synthesis (DDS) chip which allows true digital generation of the FM signal. The DDS chip is a perfectly linear modulator with superior phase-noise characteristics over the current analog voltage-controlled oscillator (VCO) approach. The DDS modulator drives a low-noise phase-locked loop (PLL) which allows upconversion to any FM channel without manual tuning. The exciter demonstrates superior microphonics immunity by separating the frequency tuning from the modulation path, thus allowing wider PLL bandwidths. The exciter can accept either the existing composite analog format or can interface with future digital sources.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Enabling AUV mapping of free-drifting icebergs without external navigation aids (2014)

This paper documents improvements in the method for offline estimation of iceberg geometry as presented by Kimball and Rock [1]. The method removes the AUV's inertial position from the equations, allowing the mission to be completed without ship-based navigation aids. This is a substantial operational advantage. Additionally, it differs from [1] in that it treats each sonar return individually, instead of abstracting multiple readings to a single point, removing a potential source of bias. Finally it reformulates the problem to simplify greatly the estimation optimization by reducing the number of needed estimation parameters. Together, these changes yield speed increases of roughly three orders of magnitude, with no loss in accuracy. The method is demonstrated via full simulation of an AUV operating around a free drifting iceberg. Additionally, an underwater sea cliff in Monterey Canyon is used as an iceberg surrogate to test the method on field data.
Surrounded by ambient persuasion (2008)

This workshop will discuss the implications of the use of Ambient Intelligence (AmI) for Persuasion. AmI allows surrounding the user with persuasive technology in their everyday life, giving the possibility for persuasive interventions just at the right time and in the right place. The workshop will focus on the potential of Ambient Persuasion for applications in the area of sustainability, health and well-being and related areas. It will also address the need for theoretical foundations and frameworks on which to ground such applications. The use of AmI for persuasion also raises a number of ethical and privacy questions. These issues play an important part in the overall user experience of persuasive AmI applications, where a special focus of this workshop lies.
Autophagy-related intrinsically disordered proteins in intra-nuclear compartments (2016)

Recent analyses indicated that autophagy can be regulated via some nuclear transcriptional networks and many important players in the autophagy and other forms of programmed cell death are known to be intrinsically disordered. To this end, we analyzed similarities and differences in the intrinsic disorder distribution of nuclear and non-nuclear proteins related to autophagy. We also looked at the peculiarities of the distribution of the intrinsically disordered autophagy-related proteins in various intra-nuclear organelles, such as the nucleolus, chromatin, Cajal bodies, nuclear speckles, promyelocytic leukemia (PML) nuclear bodies, nuclear lamina, nuclear pores, and perinucleolar compartment. This analysis revealed that the autophagy-related proteins constitute about 2.5% of the non-nuclear proteins and 3.3% of the nuclear proteins, which corresponds to a substantial enrichment by about 32% in the nucleus. Curiously, although, in general, the autophagy-related proteins share similar characteristics of disorder with a generic set of all non-nuclear proteins, chromatin and nuclear speckles are enriched in the intrinsically disordered autophagy proteins (29 and 37% of these proteins are disordered, respectively) and have high disorder content at 0.24 and 0.27, respectively. Therefore, our data suggest that some of the nuclear disordered proteins may play important roles in autophagy.
Efeitos do agrostemin em plantas de soja (Glicine max (L.) Merrill cv. IAC-8), através dos parâmetros fisiológicos: razão de área foliar, taxa assimilatória líquida e taxa de crescimento relativo (1995)

O presente estudo teve por finalidade avaliar o efeito de um estimulante vegetal, Agrostemin, no desenvolvimento de plantas de soja (Glycine max (L.) Merrill cv. IAC-8), através de alguns parâmetros que compõem a análise de crescimento. O experimento foi conduzido em casa de vegetação. Foram estudados seis tratamentos, correspondentes às seguintes dosagens, épocas e formas de aplicação: testemunha (T1); 0,125g de Agrostemin/100g sementes (T2); 0,125g de Agrostemin/l00g sementes e pulverização foliar à 333 ppm (T3); 0,125g de Agrostemin/100g sementes e pulverização foliar à 500 ppm (T4); pulverização foliar à 333 ppm (T5) e pulverização foliar à 500 ppm (T6). Realizaram-se três épocas de coleta, à intervalos de 14 dias. O experimento foi em delineamento inteiramente casualizado. Os parâmetros estudados foram: razão de área foliar (RAF), taxa assimilatória líquida (TAL) e taxa de crescimento relativo (TCR). Dentre os resultados obtidos, concluiu-se que à medida que aumentou-se a concentração, diminuiram-se os parâmetros estudados, no intervalo 71-85.
Inactivation of Kanamycin A by Phosphorylation in Pathogenic Nocardia (1991)

Among the five species of pathogenic Nocardia, i.e., N. asteroides, N. brasiliensis, N. farcinica, N. nova and N. otitidiscaviarum, all strains of N. brasiliensis and N. farcinica showed resistance to an aminoglycoside antibiotic, kanamycin A, showing the MIC (minimum inhibitory concentration) values of more than 100 micrograms/ml. This species-specific difference in sensitivity was found to be explained by the production of an inactivation enzyme, aminoglycoside 3'-phosphotransferase APH(3'). Structural studies by mass and NMR spectroscopy on the inactivated substance produced by a cell-free extract of the Nocardia confirmed the conversion of kanamycin A to an inactive substance, kanamycin A 3'-phosphate. The MIC values of N. otitidiscaviarum and N. nova for kanamycin A, on the other hand, ranged from 0.78 micrograms/ml to 100 micrograms/ml, and both species were non-producers of APH(3'). Sensitivity to the antibiotic and APH(3') productivity of N. asteroides varied depending on the strain.
Application of Molecular Cytogenetics in Fundamental and Applied Research of Potato (2011)

Department of Plant, Soil, and Entomological Sciences, University of Idaho, P.O. Box 442339, Moscow, ID 83844, USA; e-mail: jkuhl@uidaho.eduThe current era of gene inheritance analysis began with the rediscovery in the early 1900s of Gregor Mendel’s 1866 work, Experiments in Plant Hybridization (Mendel 1866). Since then a plethora of plant inheritance studies has occurred, in some of which the trait of interest was simply inherited. In general, for a trait to be defined as simply inherited, a single gene or a tightly grouped cluster of linked genes, inherited as a unit, must be responsible. At a whole plant level, this is revealed by phenotypic segregation ratios among progeny. For any given population structure, simply inherited traits segregate among progeny at expected Mendelian segregation ratios, assuming minimal infl uence by biological or environmental variables. Simply inherited traits typically include those in which a completely dominant phenotype can be qualitatively scored. Potato has many examples of simply inherited traits.
Modeling and Analysis of Energy Conservation Scheme Based on Duty Cycling in Wireless Ad Hoc Sensor Network (2010)

In sensor network, energy conservation is one of the most critical issues since sensor nodes should perform a sensing task for a long time (e.g., lasting a few years) but the battery of them cannot be replaced in most practical situations. For this purpose, numerous energy conservation schemes have been proposed and duty cycling scheme is considered the most suitable power conservation technique, where sensor nodes alternate between states having different levels of power consumption. In order to analyze the energy consumption of energy conservation scheme based on duty cycling, it is essential to obtain the probability of each state. In this paper, we analytically derive steady state probability of sensor node states, i.e., sleep, listen, and active states, based on traffic characteristics and timer values, i.e., sleep timer, listen timer, and active timer. The effect of traffic characteristics and timer values on the steady state probability and energy consumption is analyzed in detail. Our work can provide sensor network operators guideline for selecting appropriate timer values for efficient energy conservation. The analytical methodology developed in this paper can be extended to other energy conservation schemes based on duty cycling with different sensor node states, without much difficulty.
Additive manufacturing technology in spare parts supply chain: a comparative study (2016)

Additive Manufacturing (AM) technology has the potential to significantly improve supply chain dynamics. The purpose of this paper is to investigate the impact of AM on spare parts supply chain. Three supply chain scenarios are investigated in this paper, namely conventional supply chain, centralised AM-based supply chain and distributed AM-based supply chain. Based on system dynamics simulations, this paper specifically compares three supply chain scenarios, in terms of total variable cost and carbon emission. The results show the spare part supply chain utilising AM is indeed superior to the traditional one in sustainable performance. It is also expected that AM can facilitate the spare parts supply chain to achieve more economic benefits along with its development. To our knowledge, this paper is one of the early studies that explores the impact of AM on supply chain performance and quantitatively examines the superiority of utilising AM in spare parts supply chain. Some suggestions are also provided to help managers adopting AM in their spare parts supply chains.
A SIMPLE METHOD for DEMONSTRATING the PRODUCTION of GAS by BACTERIA (1898)

On February 7th lafge sloughs appeared on both buttocks in spite of the use of an air bed, etc.; later diarrhoea set in, and the patient succumbed on February 12tll, just a month after admission. The treatment main- tained throughout was in the direction of local disinfection and support- ingthe patient's strength, amputation being out of the question.
Constrained remote control of construction machine with time-varying delay and packet loss (2022)

This study developed a constrained remote control system for a crawler dump (C50-R, YANMAR Co.), which was experimentally validated in the testing field of Kajima Corporation. The remote-controlled crawler dump fulfilled the input constraints and tracked to a reference position and rotation angle in the presence of time-varying transmission delays and consecutive packet losses. The developed autonomous and remote control technology is expected to contribute to the compensation for the labor shortage in the construction industry and improve the workplace environment.
Ontogeny of prolactin and GH secretions in turkey embryos (2000)

International audience
EVENT-RELATED POTENTIAL EFFECTS IN MASKED SANDWICH PRIMING AT SHORT SOA (2012)

52nd Annual Meeting of the Society-for-Psychophysiological-Research, New Orleans, LA, SEP 19-23, 2012
Rapid Tau Aggregation and Delayed Hippocampal Neuronal Death Induced by Persistent Thrombin Signaling (2003)

Tau hyperphosphorylation, leading to self-aggregation, is widely held to underlie the neurofibrillary degeneration found in Alzheimer's disease (AD) and other tauopathies. However, it is unclear exactly what environmental factors may trigger this pathogenetic tau hyperphosphorylation. From several perspectives, the coagulation serine protease, thrombin, has been implicated in AD and activates several different protein kinase pathways but has not previously been shown how it may contribute to AD pathogenesis. Here we report that nanomolar thrombin induced rapid tau hyperphosphorylation and aggregation in murine hippocampal neurons via protease-activated receptors, which was followed by delayed synaptophysin reduction and apoptotic neuronal death. Mechanistic study revealed that a persistent thrombin signaling via protease-activated receptor 4 and prolonged downstream p44/42 mitogenactivated protein kinase activation are at least in part responsible. These results pathogenetically linked thrombin to subpopulations of AD and other tauopathies associated with cerebrovascular damage. Such knowledge may be instrumental in transforming therapeutic paradigms.
Design and implementation of a status at a glance user interface for a power distribution expert system (1993)

Expert systems are widely used in health monitoring and fault detection applications. One of the key features of an expert system is that it possesses a large body of knowledge about the application for which it was designed. When the user consults this knowledge base, it is essential that the expert system's reasoning process and its conclusions be as concise as possible. If, in addition, an expert system is part of a process monitoring system, the expert system's conclusions must be combined with current events of the process. Under these circumstances, it is difficult for a user to absorb and respond to all the available information. For example, a user can become distracted and confused if two or more unrelated devices in different parts of the system require attention. A human interface designed to integrate expert system diagnoses with process data and to focus the user's attention to the important matters provides a solution to the 'information overload' problem. This paper will discuss a user interface to the power distribution expert system for Space Station Freedom. The importance of features which simplify assessing system status and which minimize navigating through layers of information will be discussed. Design rationale and implementation choices will also be presented.
Pyro-electro-optic phase gratings (1991)

A new physical mechanism is proposed for generating transient phase gratings in transparent pyroelectric materials. The mechanism combines the pyroelectric and electro-optic effects to convert spatial intensity variations into transient phase gratings. The grating diffraction efficiency increases with a figure of merit that is proportional to the pyroelectric, electro-optic, and absorption coefficients and is inversely proportional to the specific heat. The grating response time is proportional to the specific heat and inversely proportional to the thermal conductivity. Diffraction efficiencies that approach unity are predicted in several readily available electro-optic materials with modest pulse energies from Q-switched Nd:YAG lasers. Observation with cw laser sources is also proposed. The pyro-electro-optic mechanism is compared with other known mechanisms.
Internal Fixation in Osteoporotic Bone (2003)

Orthopedic Surgery Erie County Medical Center State University of New York, Buffalo Buffalo, New York
Neopterin and Nitrite in Supernatants from Interferon-γ-treated Monocytoid Cell Lines: A Tool to Identify Bacterial Pyrogens (1999)

Summary The rabbit pyrogen assay identifies pyrogenic contaminations in drugs i.l1tend~d for parenteral use. In order to replace this test because of ethical and economical reasons, various in vitro methods have been developed in recent years. Here, we summarize our results on optimizing a test based on using interferony- treated monocytoid cell lines from man (THP-l) and mouse (RAW264.7). The read-out of the test is neopterin or nitrite, respectively, which is released into the supernatant in response to bacterial compounds. These are costimuli of the enzymes involved in neopterin and nitrite formation, i.e. GTP cyclohydrolase I and inducible nitric oxide synthase. The test reproducibly detects cell wall components from Gram-negative as well as from Gram-positive bacteria and mycobacteria. Furthermore, DNA and cell-free supernatants containing a number of bioactive but not further characterized proteins, both from Staphylococcus aureus, can be detected. Thus, this test is superior over the only in vitro alternative accepted in certain cases, namely the limulus amebocyte lysate assay. Results obtained by measuring neopterin or nitrite correlate well with formation of the endogenous pyrogen tumor necrosis factor-a, a read-out used by some other cell-based in vitro alternatives to the rabbit pyrogen test. We therefore think that the assay presented here has the potential to reduce or even replace the animal test.
ChemInform Abstract: Overriding ortho—para Selectivity via a Traceless Directing Group Relay Strategy: The Meta‐Selective Arylation of Phenols. (2014)

Abstract This protocol utilizes carbon dioxide as a traceless, transient directing group.
Comparison of effects of L/N‐type and L‐type calcium channel blockers on post‐infarct cardiac remodelling in spontaneously hypertensive rats (2020)

Hypertension and coronary events are becoming more prevalent in aging societies, and myocardial infarction usually occurs in calcium channel blocker (CCB)-treated hypertensive patients. We herein compared the effects of cilnidipine, an L/N-type CCB and amlodipine, an L-type CCB, on post-infarct left ventricular (LV) remodelling in spontaneously hypertensive rats (SHRs). Male SHRs were subjected to 30 minutes of left coronary artery occlusion followed by reperfusion (MI group). The administration of cilnidipine (10 mg/kg/d; MI + Cil group) or amlodipine (10 mg/kg/d; MI + Aml group) was initiated one week before surgery and continued for five weeks. Both CCBs decreased blood pressure. Four weeks after surgery, cilnidipine, but not amlodipine, attenuated LV dilatation, fractional shortening impairments, end-diastolic pressure elevations, and tau elongation. In the non-infarct region, myocyte hypertrophy and brain natriuretic peptide (BNP) mRNA levels were similarly attenuated by both CCBs. On the other hand, interstitial fibrosis, the mRNA expression of collagen type III and transforming growth factor (TGF) β and immunohistological TGF β protein expression in the non-infarct region were reduced more in the MI + Cil group than in the MI + Aml group. Additionally, elevated angiotensin-converting enzyme activity and interstitial noradrenaline concentrations in the non-infarct region were reduced by cilnidipine. These results suggest that cilnidipine reduced cardiac noradrenaline concentrations and inhibited the renin-angiotensin system, which attenuated post-infarct remodelling more than amlodipine in hypertensive rats.
Supporting secure transcoding in JPSEC (2005)

The capture, processing, delivery, and display or printing of digital images is important today and will become even more important in the future. Important additional future challenges include the remote browsing of images, image adaptation to support diverse clients, and providing security services such as confidentiality and authentication. In this context, an important functionality is <i>secure transcoding</i>: providing end-to-end security between the content creator and the content consumer, while enabling a potentially untrusted mid-network node or proxy to adapt the content to be best matched for delivery to the consumer - where the adaptation is performed without requiring the node or proxy to unprotect (i.e., decrypt) the content. In prior work, secure transcoding was shown to be possible through a framework referred to as Secure Scalable Streaming, which was originally designed for video streaming applications. Secure transcoding was identified as being possible within the ISO/IEC JPEG-2000 Security (JPSEC) standardization effort, and this paper describes how the JPSEC standard was designed to support rate-distortion (R-D) optimized secure transcoding.
Análisis del rendimiento académico en la cátedra de fisiología y fisiopatología usando como herramienta el aula virtual (2017)

espanolEl objetivo de la investigacion es analizar el impacto de emplear el aula virtual en los procesos de ensenanza-aprendizaje de los estudiantes universitarios que cursan la catedra de Fisiologia y Fisiopatologia I. Se realizo una investigacion cuantitativa de tipo descriptiva, comparativa y longitudinal. La tecnica fue la encuesta y se trabajo con un universo de 67 estudiantes universitarios de la Facultad de Medicina en el periodo marzo–agosto 2016. En una primera etapa se diagnostico sobre herramientas TIC al universo y en la segunda etapa, se establecio que al paralelo B se le facilitaria la catedra mediante una metodologia tradicional de ensenanza y al paralelo A mediante el aula virtual. Como resultado, se obtuvo que el grupo experimental ha alcanzado un mejor desempeno academico, superando al de control por 2,2 puntos en el promedio general. Se concluyo que el uso de aulas virtuales tiene una influencia positiva en el proceso de ensenanza-aprendizaje. EnglishThe objective of the research is to analyze the impact of using the virtual classroom in the teaching-learning processes of the university students who study the physiology and pathophysiology subject. We conducted a quantitative descriptive, comparative, and longitudinal research. The technique used was the survey and we worked with a universe of 67 university students of the Faculty of Medicine in the period March-August 2016. In a first stage was diagnosed on ICT tools to the universe and in the second stage, it was established that parallel B would be facilitated by a traditional teaching methodology and parallel A through the virtual classroom. As a result, the experimental group achieved a better academic performance, surpassing the control group by 2,2 points in the average. It was concluded that the use of virtual classrooms has a positive influence on the teaching-learning process.
Algorithms for computing QoS paths with restoration (2005)

There is a growing interest among service providers to offer new services with Quality of Service (QoS) guarantees that are also resilient to failures. Supporting QoS connections requires the existence of a routing mechanism, that computes the QoS paths, i.e., paths that satisfy QoS constraints (e.g., delay or bandwidth). Resilience to failures, on the other hand, is achieved by providing, for each primary QoS path, a set of alternative QoS paths used upon a failure of either a link or a node. The above objectives, coupled with the need to minimize the global use of network resources, imply that the cost of both the primary path and the restoration topology should be a major consideration of the routing process. We undertake a comprehensive study of problems related to finding suitable restoration topologies for QoS paths. We consider both bottleneck QoS constraints, such as bandwidth, and additive QoS constraints, such as delay and jitter. This is the first study to provide a rigorous solution, with proven guarantees, to the combined problem of computing QoS paths with restoration. It turns out that the widely used approach of disjoint primary and restoration paths is not an optimal strategy. Hence, the proposed algorithms construct a restoration topology , i.e., a set of bridges, each bridge protecting a portion of the primary QoS path. This approach guarantees to find a restoration topology with low cost when one exists.