gebhart/patrepeval huggingface dataset:
Interface physics in microporous media : LDRD final report. (2008)

This document contains a summary of the work performed under the LDRD project entitled 'Interface Physics in Microporous Media'. The presence of fluid-fluid interfaces, which can carry non-zero stresses, distinguishes multiphase flows from more readily understood single-phase flows. In this work the physics active at these interfaces has been examined via a combined experimental and computational approach. One of the major difficulties of examining true microporous systems of the type found in filters, membranes, geologic media, etc. is the geometric uncertainty. To help facilitate the examination of transport at the pore-scale without this complication, a significant effort has been made in the area of fabrication of both two-dimensional and three-dimensional micromodels. Using these micromodels, multiphase flow experiments have been performed for liquid-liquid and liquid-gas systems. Laser scanning confocal microscopy has been utilized to provide high resolution, three-dimensional reconstructions as well as time resolved, two-dimensional reconstructions. Computational work has focused on extending lattice Boltzmann (LB) and finite element methods for probing the interface physics at the pore scale. A new LB technique has been developed that provides over 100x speed up for steady flows in complex geometries. A new LB model has been developed that allows for arbitrary density ratios, which has been a significant obstacle in applying LB to air-water flows. A new reduced order model has been developed and implemented in finite element code for examining non-equilibrium wetting in microchannel systems. These advances will enhance Sandia's ability to quantitatively probe the rich interfacial physics present in microporous systems.
Microscopic Structure of the Large Intestinal Mucosa in Piglets during an Antibiotic-Associated Diarrhea. (2003)

Antibiotic-associated diarrhea (AAD) is caused by the treatments of broad-spectrum antimicrobials that seriously affect the activity and composition of the large intestinal microflora. The pathogenic bacteria or low concentration of short-chain fatty acids (SCFAs) has been repeatedly discussed in relation to AAD. Recently, we reported the detection of a large amount of succinate and lactate in the diarrheal feces in AAD-induced piglets. In this study, we investigated histologically the large intestinal mucosa in AAD-induced piglets, in which succinate and lactate were accumulated. AAD was induced in the piglets by an oral dose of polymyxin B sulfate (PL) or by an intra-muscular injection of enrofloxacin (ERFX). When the piglets were defecating diarrheal feces with a high concentration of succinate and/or lactate, the large intestine was removed and separated into four segments (cecum, gyri centripetales, gyri centrifugales, and rectum). Healthy piglets were used as the control. In the AAD-induced piglets, the lamina propria was edematous in the gyri centripetales. Piglets treated with ERFX were also edematous in gyri centrifugales. These edematous lamina propria contained larger amounts of inflammatory cells than observed in control tissues. ERFX-treated piglets had a more shallow crypt than PL-treated and control piglets. The mucosal tissue of the large intestine was more seriously damaged in the ERFX- than in the PL-treated piglets, which might have been caused by the high succinate and low SCFAs concentration in the digesta.
Requirements to signal processing for visualizing surfaces from three-dimensional ultrasound data sets (1999)

Three-dimensional ultrasound can be regarded as the generalization of the traditional 2-D technique with the aim to provide a ‘‘tomographic’’ acquisition of the body interior, and moreover, to visualize surfaces of internal organs and pathology, such as fetuses, bone, liver, vessels, skin, brain, but also cysts, tumors, etc. The first requirement for visualizing a surface is obviously the ability of a system to provide mostly clear, sharply defined, high contrast surfaces of internal interfaces between tissue types. The presence of speckle (e.g., parenchyma within liver, amniotic fluid, etc.) greatly reduces the ability of presenting surfaces. ‘‘Ideal’’ surfaces from the visualization point of view have a small width (i.e., narrow transition zone between different tissues), are smooth, high contrast, continuous, gapless, and show the same gradient and average intensity. Although these requirements can hardly be fulfilled all at once, one wishes/expects that selective image processing can help overcome several of these difficulties. Numerous examples of this group’s previous works demonstrating all 3-D surface visualization drawbacks listed above, together with some image-processing-based improvement techniques proposed so far, will be presented.
Power-factor correction with interleaved boost converters in continuous-inductor-current mode (2002)

The operation and design trade-offs of the interleaved boost converter in continuous inductor-current mode in a high-power-factor preregulator circuit are investigated. By using interleaved converters, an overall reduction of boost inductor and electromagnetic interference (EMI) filter volume can be achieved, together with reduced switching losses. The problem of unequal load sharing between the interleaved power stages with average current control is pointed out, and a practical solution is recommended. EMI filter design considerations and experimental data taken from a 3 kW converter are presented.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
DNA strand scission and free radical production in menadione-treated cells. Correlation with cytotoxicity and role of NADPH quinone acceptor oxidoreductase. (1992)

Menadione (MD; 2-methyl-1,4-naphthoquinone), a redox cycling quinone was shown to induce single (ss)- and double (ds)-strand DNA breaks in human MCF-7 cells. This DNA damage was mediated via the hydroxyl radical as evidenced by electron spin resonance spectroscopy (ESR) studies utilizing the spin trap, 5,5-dimethyl-1-pyrroline-1-oxide. The free radical production and DNA damage were shown to play a role in MD cytotoxicity as revealed by the reversal of MD toxicity and inhibition of hydroxyl radical production by exogenously added catalase. The role of NADPH quinone acceptor oxidoreductase in the metabolism of MD was evaluated. Purified quinone acceptor oxidoreductase in combination with MD resulted in the production of significant levels of the hydroxyl radical as measured by ESR. Dicumarol, an inhibitor of quinone acceptor oxidoreductase, decreased the production of the hydroxyl radical and attenuated DNA strand breaks in MCF-7 cells treated with MD.
Synthesis and characterization of ZnO nanoparticles: A review (2019)

Zinc oxide is an inorganic compound and usually appears as a white powder. It also called a multifunctional material because of to its unique physical and chemical properties. Zinc oxide nanoparticles were successfully synthesized by a sol-gel method, precipitation method, green leaf extract, and microwave method, wet chemical and hydrothermal method. Different compositions of zinc oxides nano composites were characterized using X-Ray Diffractometer, Scanning Electron Microscope, Transmission Electron Microscope, Fourier Transform Infrared spectrometer and Photoluminescence Spectrofluorophotometer studies. The X-ray diffraction studies reveals that the synthesized ZnO nanoparticles have wurtzite structure and the particle size varies from 20 to 30 nm. Scanning Electron Microscopic investigation reveals that the surface morphology of ZnO nanoparticle is spherical in hydrothermal process and varies to flower like arrangement in sol-gel process. Crystalline oxide powders, combined with other materials, provide possibilities for obtaining improved chemical, mechanical, optical or electrical properties.
Voice conversion in high-order eigen space using deep belief nets (2013)

This paper presents a voice conversion technique using Deep Belief Nets (DBNs) to build high-order eigen spaces of the source/target speakers, where it is easier to convert the source speech to the target speech than in the traditional cepstrum space. DBNs have a deep architecture that automatically discovers abstractions to maximally express the original input features. If we train the DBNs using only the speech of an individual speaker, it can be considered that there is less phonological information and relatively more speaker individuality in the output features at the highest layer. Training the DBNs for a source speaker and a target speaker, we can then connect and convert the speaker individuality abstractions using Neural Networks (NNs). The converted abstraction of the source speaker is then brought back to the cepstrum space using an inverse process of the DBNs of the target speaker. We conducted speakervoice conversion experiments and confirmed the efficacy of our method with respect to subjective and objective criteria, comparing it with the conventional Gaussian Mixture Model-based method.
A new technique for modeling neuronal connectivity using human pluripotent stem cells (2015)

We have developed a hPSC-based system for producing connections between neurons from two brain regions, neocortex and midbrain. Future experiments could employ modifications of this method to examine connections between any two brain regions or neuronal subtypes that can be produced from hPSCs in vitro.
The Platelet P2 Receptors in Thrombosis (2005)

Adenosine diphosphate (ADP) and adenosine triphosphate (ATP) play a crucial role in hemostasis and thrombosis, and their receptors are potential targets for antithrombotic drugs. The ATP-gated channel P2X (1) and the two G protein-coupled P2Y (1) and P2Y (12) ADP receptors selectively contribute to platelet aggregation. Because of its central role in the formation and stabilization of a thrombus, the P2Y (12) receptor is a well-established target of antithrombotic drugs such as clopidogrel, which has proven efficacy in many clinical trials and experimental models of thrombosis. Competitive P2Y (12) antagonists have also been shown to be effective in experimental thrombosis as well as in several clinical trials. Studies in P2Y (1) and P2X (1) knockout mice and experimental thrombosis models using selective P2Y (1) and P2X (1) antagonists have shown that, depending on the conditions, these receptors could also be potential targets for new antithrombotic drugs. Because both P2X (1) and P2Y (1) receptor inhibition result in milder prolongation of the bleeding time as compared with P2Y (12) inhibition, the idea is put forward that combinations of P2 receptor antagonists could improve efficacy with diminished hemorrhagic risk. However, further studies with stronger and more selective P2 receptor antagonists are required to validate such a point of view.
Boosting Contrast of Cryo-EM Images Without a Phase Plate (2015)

Transmission electron microscopy (TEM) imaging of frozen-hydrated biological requires careful selection of exposure in order to balance the goal of maximizing image contrast with the necessity of minimizing radiation damage In general, increasing the total exposure of each image improves lowfrequency contrast at the expense of high-resolution information due to radiation damage.
Co-location of mobile devices with audio and wireless interfaces (2009)

Tese de mestrado integrado. Engenharia Electrotécnica e de Computadores - Major de Telecomunicações. Faculdade de Engenharia. Universidade do Porto. 2008
Simulated RADAR Soundings of Models of the Martian Subsurface (2020)

Interpreting and understanding ground penetrating RADAR (GPR) measurements of the Martian shallow subsurface is directly linked to the capability to correctly (and efficiently) simulate the electromagnetic wave propagation, taking into account all relevant effects at multiple scales. This is especially crucial for broadband RADAR instruments like WISDOM, a payload of the ExoMars “Rosalind Franklin” rover, scheduled for 2022. We present preliminary simulation results for models of the shallow Martian subsurface using a raytracing-based simulation tool in this contribution.
The raytracing tool developed explicitly for GPR applications, can be applied to heterogeneous and inhomogeneous media and includes the antenna characteristics of the WISDOM instrument and the rover structures. It simulates the wave propagation in complex media, taking into account polarization effects. The method is a hybrid between conventional raytracing (SBR), differential raytracing, and physical optics. The simulation complexity can be controlled and weighed against approximation necessary for the specific simulation case and the expected results. This tool can simulate electrically large domains with an acceptable accuracy yielding good predictions of the propagation properties in Martial soil while being significantly less computationally expensive than conventional full-wave solvers like FEM or the Finite-Differences in Time-Domain Method.
From hypothesized structural, geophysical, and material models of Oxia Planum’s subsurface, geoelectrical simulation models are derived as input for the simulation tool. Synthetic radargrams are generated for these models, giving insight into the capabilities and expected outcome of the WISDOM instrument and the simulation tool.
Seville orange juice-felodipine interaction: Comparison with dilute grapefruit juice and involvement of furocoumarins (2001)

Seville orange juice and grapefruit juice interact with felodipine by a common mechanism, which is probably inactivation of intestinal CYP3A4. Bergamottin and 6',7'-dihydroxybergamottin may be "marker substances" in foods for this interaction. The lack of interaction between Seville orange juice and cyclosporine (INN, ciclosporin) suggests that grapefruit juice may also inhibit intestinal P-glycoprotein, whereas Seville orange juice may selectively "knock out" intestinal CYP3A4.
Research on low speed control of permanent magnet synchronous motor based on state observer (2011)

This paper presents an instantaneous speed detection method of permanent magnet synchronous motor (PMSM) based on state observer. When a low resolution incremental-type encoder is used for speed detection, the conventional detection methods will lead delay and error which readily cause instability of the control system, in particular, when the number of pulses is few in one detection period. By using the observed rotor speed, the control system performance can be greatly improved in very low speed range, even with low resolution encoder. In practice, it is very difficult to keep the parameters of the observer and the actual system consistent with each other at any time, so this paper analyzes and demonstrates it is very robust to parameter variations. To further improve the accuracy of the observed speed in very low speed, a novel prediction method of the rotor position is designed, the simulation results are given, and the validity of this method is proved.
Superacid-Treated Silicon Surfaces: Extending the Limit of Carrier Lifetime for Photovoltaic Applications (2017)

Minimizing carrier recombination at interfaces is of extreme importance in the development of high-efficiency photovoltaic devices and for bulk material characterization. Here, we investigate a temporary room temperature superacid-based passivation scheme, which provides surface recombination velocities below 1 cm/s, thus placing our passivation scheme amongst state-of-the-art dielectric films. Application of the technique to high-quality float-zone silicon allows the currently accepted intrinsic carrier lifetime limit to be reached and calls its current parameterization into doubt for 1 Ω·cm n-type wafers. The passivation also enables lifetimes up to 65 ms to be measured in high-resistivity Czochralski silicon, which, to our knowledge, is the highest ever measured in Czochralski-grown material. The passivation strategies developed in this work will help diagnose bulk lifetime degradation under solar cell processing conditions and also help quantify the electronic quality of new passivation schemes.
Analysis of the DNN-based SRE systems in multi-language conditions (2016)

This paper analyzes the behavior of our state-of-the-art Deep Neural Network/i-vector/PLDA-based speaker recognition systems in multi-language conditions. On the “Language Pack” of the PRISM set, we evaluate the systems' performance using the NIST's standard metrics. We show that not only the gain from using DNNs vanishes, nor using dedicated DNNs for target conditions helps, but also the DNN-based systems tend to produce de-calibrated scores under the studied conditions. This work gives suggestions for directions of future research rather than any particular solutions to these issues.
Missy Piggle-Wiggle and the Sticky-Fingers Cure (2019)

Now I’m sure many of you have heard of Mrs. Piggle Wiggle, the zany lady who could cure any child of their bad behaviors. But have you heard about her niece, Missy? Missy has been asked to help with the farm and the upside-down house while her uncle and aunt are off on adventures. Missy does her best to keep everything running smoothly in the neighborhood while she and her animals are under quarantine due to a magical disease. Being stuck inside doesn’t stop her from curing many of the neighborhood children of challenges of their own. Missy has a cure for it all.
Prostatic Specific Antigen, Prostatic Acid Phosphatase and Acid Phosphatase in Patients with Prostate Cancer and Benign Prostatic Hyperplasia (1987)

No AccessJournal of Urology1 Jun 1987Prostatic Specific Antigen, Prostatic Acid Phosphatase and Acid Phosphatase in Patients with Prostate Cancer and Benign Prostatic Hyperplasia Nelson N. Stone, Jerome S. Nisselbaum, Raisa Stankievic, Delia Schwartz, and Morton K. Schwartz Nelson N. StoneNelson N. Stone More articles by this author , Jerome S. NisselbaumJerome S. Nisselbaum More articles by this author , Raisa StankievicRaisa Stankievic More articles by this author , Delia SchwartzDelia Schwartz More articles by this author , and Morton K. SchwartzMorton K. Schwartz More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)75506-1AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Prostatic Specific Antigen, Prostatic Acid Phosphatase and Acid Phosphatase in Patients with Prostate Cancer and Benign Prostatic Hyperplasia." The Journal of Urology, 137(6), p. 192A © 1987 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 137Issue 6June 1987Page: 192A Advertisement Copyright & Permissions© 1987 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Nelson N. Stone More articles by this author Jerome S. Nisselbaum More articles by this author Raisa Stankievic More articles by this author Delia Schwartz More articles by this author Morton K. Schwartz More articles by this author Expand All Advertisement PDF DownloadLoading ...
ÜBER DIE KONFIGURATION DES 19‐NOR‐10ξ, 14β, 17α‐PROGESTERONS (1958)

Abstract Vergleiche von Rotationsdispersionskurven erlauben den Schluß, daß beim 19‐Nor‐10ξ, 14β, 17α‐progesteron und einer Reihe verwandter Verbindungen am Kohlenstoffatom 10 die „natürliche”︁ Konfiguration vorliegt. In den entsprechenden Namen ist daher das bisher gebrauchte Zeichen „10ξ”︁ wegzulassen.
287. Primary photochemical reactions. Part X. The photolysis of cyclic ketones in the gas phase (1938)

C. H. Bamford and R. G. W. Norrish, J. Chem. Soc., 1938, 1521 DOI: 10.1039/JR9380001521
Bisystem Oscillation Theory of Stars - Part Two - Excitation Mechanisms (1992)

The excitation mechanism of the stellar oscillation due to the interaction of the gas with the radiation are investigated according to the bisystem oscillation theory. The equation for the temporal variation in the kinetic energy of the oscillation and the expression for the work integral valid in the nonequilibrium diffusion are derived. It is found that the excitation mechanisms, which transform the radiation energy into the oscillation one, are of two types, i.e. the modulation mechanism and frozen temperature mechanism, which result from the nonequilibrium between the gas and radiation.
Focusing of electric-dipole waves in the Debye and Kirchhoff approximations (1997)

We compare the Debye and Kirchhoff approximations for focusing of electromagnetic waves, with special emphasis on the focusing of converging electric-dipole waves. Numerical solutions for the spectral amplitude of the incident converging wave and for the focused field are provided in both approximations for a variety of Fresnel numbers and f-numbers. Comparisons of numerical solutions in Kirchhoff and Debye approximations show that for systems of Fresnel numbers larger than 20 and f-numbers less than 0.5, both approximations give indistinguishable results for focused electric-dipole waves. At low Fresnel numbers, the Kirchhoff approximation gives the best results irrespective of the f-number, as in the scalar case. The focal shift depends mainly on the Fresnel number, but at low Fresnel numbers, a reduction of the f-number gives an increase of the relative focal shift.
Location- and orientation-controlled, large single grain silicon induced by pulsed excimer laser crystallization (2010)

We studied pulsed laser induced epitaxy of silicon using a seeding wafer to realize location-and orientation-control of silicon grain. Silicon grains as large as 4 µm × 4 µm with mostly the preferred (100) orientation area were obtained on top of contact openings through SiO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> to seeding silicon (100) wafer. The orientation of the seed is inherited by a-Si during the solidification phase of molten-Si. The maximum process temperature of this process is 545 °C which is for LPCVD deposition of a-Si. This layer is suitable for high mobility SOI CMOS devices which serve as building blocks for monolithic 3D integration.
Targeted ablation of Arnt in mouse epidermis results in profound defects in desquamation and epidermal barrier function (2006)

The molecular mechanisms of skin adaptation to the environmental stress are poorly understood. The aryl hydrocarbon receptor nuclear translocator (Arnt) lies at the intersection of several crucial adaptive pathways. Nevertheless, its role in adaptation of the skin to environmental stress has just begun to be unraveled. Here we show that Arnt is expressed in human and mouse skin in a developmentally dependent manner. Targeted K14-driven deletion of Arnt in the mouse epidermis resulted in early postnatal death, associated with a failure of epidermal barrier function. Gene expression profiling of Arnt-null mouse epidermis revealed upregulation of genes of the epidermal differentiation complex on mouse chromosome 3, including S100a genes (S100a8, S100a9, S100a10) and genes coding for small proline-rich proteins (Sprr1a, Sprr2i, Sprr2j, Sprrl1). HPTLC analysis showed significant accumulation of Cer[NS] and Cer[NH] ceramide species in Arnt-null epidermis, suggesting alterations in lipid metabolism. Continuous retention of corneosomes in Arnt-null epidermis that resulted in an abnormally dense corny layer and impaired desquamation was associated with upregulation of Slpi, an inhibitor of stratum corneum chymotryptic enzyme (SCCE) that plays a key role in corneosome degradation. The functional defects in Arnt-null mouse epidermis underscore the crucial role of Arnt in the maintenance of epidermal homeostasis, especially during the perinatal transition to the ex utero environment.