gebhart/patrepeval huggingface dataset:
STRATEGI MANAJEMEN MEMBANGUN KUALITAS PELAYANAN MENGGUNAKAN IMPORTANCE PERFORMANCE AANALISIS (IPA), POTENSIAL GAIN IN CUSTOMER VALUE INDEX (PGCV) DAN SERQUAL DI RSUD SULTAN IMANUDDIN PANGKALAN BUN KALIMANTAN TENGAH (2023)

Kota Pangkalan Bun Barat memiliki RSUD Sultan Imanuddin yang merupakan rumah sakit milik Pemerintah Daerah Kabupaten Kotawaringin Barat dan satu-satunya di Kabupaten Kotawaringin Barat, sehingga masyarakat yang tinggal di lingkup Kabupaten Kotawaringin Barat berobat dan memeriksakan kesehatannya di Rumah Sakit Umum Daerah tersebut. Pada penelitian ini, peneliti akan menganalisis kualitas pelayanan Rumah Sakit Umum Daerah Sultan Imanuddin Pangkalan Bun Kabupaten Kotawaringin Barat Kalimantan Tengah menggunakan Metode Importance Performance Analysis dan Potential Gain in Customer Values. Penelitian ini menggunakan metode Importance Performance Analysis (IPA). Populasi dalam penelitian ini adalah pasien ruang rawat inap yang dirawat dalam kurun waktu bulan Oktober-November 2022 di Bangsal Bedah (bangsal Meranti RSUD Sultan Imanuddin Pangkalan Bun). Data dikumpulkan menggunakan kuesioner yang telah tervalidasi. Dilakukan uji analisis Importance Performance Analysis dan Potential Gain Customer untuk menghitung tingkat kesesuaian antara tingkat kepentingan dan tingkat kepuasan pasien. Hasil analisis Metode IPA didapatkan Item yang berada pada kuadran A adalah: dimensi tangible (wujud/kenyataan), yaitu tata letak dan desain rumah sakit fasilitas RSUD. Sementara dari hasil perhitungan indeks PGCV diketahui bahwa prioritas yang harus dilakukan perbaikan adalah lokasi rumah sakit yang nyaman dan mudah dikases yang memiliki indeks PGCV tertinggi sebesar 5,47. Pioritas yang harus dilakukan perbaikan adalah terkait lokasi, sarana dan prasarana dalam menunjang pelayanan pasien, atribut yang harus dipertahankan pelayanannya adalah pemanatuan staff RS terhadap perkembangan penyakit.
Personality and diabetes (2010)

Diabetes is stressful. Holmes and Rahe developed a scale, which ranked life events as stressors. The sixth most stressful of 43 personal events was personal illness, and the 11th was a major change in health behaviour. These life events both apply to living with diabetes, which suggests that diabetes is highly ranked as a personal stressor.
Reaction of carbon oxides with an ethylene-bridged PH/B Lewis pair (2021)

The reaction of 2,4,6-tri(tert-butyl)phenyl vinyl phosphane with Piers' borane [HB(C6F5)2] gave the ethylene-bridged PH/B frustrated Lewis pair (FLP) system. It is a monomer at high temperature (>323 K), but exists as an associated 12-membered macrocyclic trimer below 273 K. The PH/B FLP splits dihydrogen and serves as a metal-free hydrogenation catalyst. It adds carbon dioxide. It serves as a PH/B template for the reduction of carbon monoxide by the HB(C6F5)2 borane to the formyl stage. The resulting six membered P/B/O containing heterocycle is opened upon treatment with pyridine and it reacts with benzaldehyde in a boron mediated Claisen-Tishchenko reaction.
[Biomarkers for early diagnosis of Alzheimer's disease]. (2015)

Alzheimer's disease is responsible for 40-50% of dementia cases. Future treatment may include disease-modifying compounds unlikely to be efficient if administered late in the course, thus necessitating early diagnosis. Furthermore, revised diagnostic research criteria that include biomarkers of pathological accumulation of cortical beta-amyloid (decreased beta-amyloid in cerebrospinal fluid and amyloid imaging) and neurodegeneration (structural MRI and 18F-FDG-PET), have been published. Future research is needed to determine specific evidence-based application of these biomarkers in the clinic as well as discovery of novel biomarkers.
Scalable Privacy-Preserving Distributed Learning (2021)

Abstract In this paper, we address the problem of privacy-preserving distributed learning and the evaluation of machine-learning models by analyzing it in the widespread MapReduce abstraction that we extend with privacy constraints. We design spindle (Scalable Privacy-preservINg Distributed LEarning), the first distributed and privacy-preserving system that covers the complete ML workflow by enabling the execution of a cooperative gradient-descent and the evaluation of the obtained model and by preserving data and model confidentiality in a passive-adversary model with up to N −1 colluding parties. spindle uses multiparty homomorphic encryption to execute parallel high-depth computations on encrypted data without significant overhead. We instantiate spindle for the training and evaluation of generalized linear models on distributed datasets and show that it is able to accurately (on par with non-secure centrally-trained models) and efficiently (due to a multi-level parallelization of the computations) train models that require a high number of iterations on large input data with thousands of features, distributed among hundreds of data providers. For instance, it trains a logistic-regression model on a dataset of one million samples with 32 features distributed among 160 data providers in less than three minutes.
Acoustic energy harvesting using an electromechanical Helmholtz resonator (2008)

This paper presents the development of an acoustic energy harvester using an electromechanical Helmholtz resonator (EMHR). The EMHR consists of an orifice, cavity, and a piezoelectric diaphragm. Acoustic energy is converted to mechanical energy when sound incident on the orifice generates an oscillatory pressure in the cavity, which in turns causes the vibration of the diaphragm. The conversion of acoustic energy to electrical energy is achieved via piezoelectric transduction in the diaphragm of the EMHR. Moreover, the diaphragm is coupled with energy reclamation circuitry to increase the efficiency of the energy conversion. Lumped element modeling of the EMHR is used to provide physical insight into the coupled energy domain dynamics governing the energy reclamation process. The feasibility of acoustic energy reclamation using an EMHR is demonstrated in a plane wave tube for two power converter topologies. The first is comprised of only a rectifier, and the second uses a rectifier connected to a flyback converter to improve load matching. Experimental results indicate that approximately 30 mW of output power is harvested for an incident sound pressure level of 160 dB with a flyback converter. Such power level is sufficient to power a variety of low power electronic devices.
‘There is no progression in prevention’ – The experiences of mental health nurses working with repeated self‐harm (2019)

Caring for people who self-harm is an everyday experience for mental health nurses and an important part of their role. How mental health nurses respond to and support those who self-harm can have a significant impact on the outcomes for service users and their intentions to seek help in the future. Repeated self-harm can be a particularly challenging phenomenon as it is often misunderstood and can have a negative impact on the therapeutic relationship. This qualitative descriptive study aims to explore how mental health nurses understand and work with repeated self-harm. Nine nurses working in a range of mental health settings within one service participated in semi-structured interviews which were analysed thematically. Findings are presented in two themes exploring participants' perceptions and understanding of repeated self-harm, and the process of learning to work with repeated self-harm, and are reported in accordance with the consolidated criteria for reporting qualitative research guidelines (COREQ). Participants reported that nursing practice relating to repeated self-harm remains largely focused on maintenance of safety and prevention of self-harm despite the identification that this often does not work. It was accepted that there is sometimes a lack of understanding about the function of self-harm; however, participants reported understanding increased following specific education about self-harm. Participants also identified the potential for more empowering and recovery-orientated responses, including the utilization of harm reduction approaches, to the care of those who repeatedly self-harm.
Study of visual evoked potentials in diabetics without retinopathy: correlations with clinical findings and polyneuropathy (2009)

To evaluate central optic pathways' involvement in diabetics, visual evoked potentials (VEP), in particular the latency of positive peak (LP100), were studied in 35 patients without retinopathy (4 insulin-dependent, 31 non-insulin-dependent) and 35 normal controls using reversal pattern stimulation. LP100 was significantly delayed in diabetics at both binocular and monocular stimulation. Furthermore, the delay in LP100 was significantly longer in the diabetics with polyneuropathy than in those without, particularly after binocular stimulation. A positive correlation was found between latencies of VEP and HbA1, duration of disease, and neurologic score. VEP measurement seems a simple and sensitive method for detecting early alterations in central optic pathways in diabetics.
Dual Crosslinked-Network Self-Healing Composite Hydrogels Exhibit Enhanced Water Adaptivity and Reinforcement (2022)

Despite the self-healing and mechanical stimuli and responsive merits of wearable hydrogel devices, achieving efficient strategies to improve their properties (i.e., mechanical strength and water adaptivity) remains challenging. Hydrogels with multinetwork structures usually display exceptional high mechanical strength via their unique macromolecular hierarchical structure comprising two or more interlaced networks. Herein, we exploit polyol/borax systems to design self-healing bicomponent polymer network hydrogels composed of polyvinyl alcohol (PVA) and guar. Our results have shown that due to the formation of bicomponent network structures, considerable reinforcement in the storage modulus and viscoelastic behaviors is achieved. Such improvements are accompanied by enhanced water resistance, which is in sharp contrast to the water-soluble nature of the PVA hydrogel. Moreover, the fabricated composite hydrogel well keeps the self-healing and mechanical stimulus-responsive merits and does not cause a decrease in thermal stability.
Закономерности формирования структуры и свойств ковочных сплавов системы AL-ZN-MG-CU c различным содержанием основных легирующих компонентов, микродобавок и примесей (2012)

The complex studies have been made to investigate the influence of the main alloying elements Zn, Mg, Cu, small additives Zr, Sc, Ag, impurities Fe and Si on the strength, fracture toughness, fatigue properties, corrosion resistance, microstructure parameters (dispersoids, strengthening precipitates, recrystallization degree, grain size) of forged semiproducts manufactured from high strength forgeable alloys of Al-Zn-Mg-Cu system.
Clinical applications of molecular biology for infectious diseases. (2006)

Molecular biological methods for the detection and characterisation of microorganisms have revolutionised diagnostic microbiology and are now part of routine specimen processing. Polymerase chain reaction (PCR) techniques have led the way into this new era by allowing rapid detection of microorganisms that were previously difficult or impossible to detect by traditional microbiological methods. In addition to detection of fastidious microorganisms, more rapid detection by molecular methods is now possible for pathogens of public health importance. Molecular methods have now progressed beyond identification to detect antimicrobial resistance genes and provide public health information such as strain characterisation by genotyping. Treatment of certain microorganisms has been improved by viral resistance detection and viral load testing for the monitoring of responses to antiviral therapies. With the advent of multiplex PCR, real-time PCR and improvements in efficiency through automation, the costs of molecular methods are decreasing such that the role of molecular methods will further increase. This review will focus on the clinical utility of molecular methods performed in the clinical microbiology laboratory, illustrated with the many examples of how they have changed laboratory diagnosis and therefore the management of infectious diseases.
Gene Expression Profiling Shows Medullary Breast Cancer Is a Subgroup of Basal Breast Cancers (2006)

Medullary breast cancer (MBC) is a rare but enigmatic pathologic type of breast cancer. Despite features of aggressiveness, MBC is associated with a favorable prognosis. Morphologic diagnosis remains difficult in many cases. Very little is known about the molecular alterations involved in MBC. Notably, it is not clear whether MBC and ductal breast cancer (DBC) represent molecularly distinct entities and what genes/proteins might account for their differences. Using whole-genome oligonucleotide microarrays, we compared gene expression profiles of 22 MBCs and 44 grade III DBCs. We show that MBCs are less heterogeneous than DBCs. Whereas different molecular subtypes (luminal A, luminal B, basal, ERBB2-overexpressing, and normal-like) exist in DBCs, 95% MBCs display a basal profile, similar to that of basal DBCs. Supervised analysis identified gene expression signatures that discriminated MBCs from DBCs. Discriminator genes are associated with various cellular processes related to MBC features, in particular immune reaction and apoptosis. As compared with MBCs, basal DBCs overexpress genes involved in smooth muscle cell differentiation, suggesting that MBCs are a distinct subgroup of basal breast cancer with limited myoepithelial differentiation. Finally, MBCs overexpress a series of genes located on the 12p13 and 6p21 chromosomal regions known to contain pluripotency genes. Our results contribute to a better understanding of MBC and of mammary oncogenesis in general.
Stem cell and Regenerative Medicine: Industry Highlights (2012)

Cellular Dynamics International, WI, USA (www.cellulardynamics.com),continued its domination in the area of induced pluripotent stem cells.In addition to its portfolio of iCell ® products, human-induced pluripotent stem cell-derived cardiomyocyes, neurons, hepatocytes and endothelial cells, the company launched the new service MyCell™.MyCell is offering cell reprogramming, genetic engineering and cell differentiation from customers' samples.Cells from a variety of tissue sources can be reprogrammed with genome nonintegrating episomal vectors under feeder-free conditions.
Photo-triggered ODN manipulation on DNA chip (2005)

DNA microarray is a powerful tool allowing simultaneous detection of many different target molecules present in a sample. We developed the photo-triggered ODN manipulation on DNA chip, and analyzed efficiency and discrimination of surface photoligation.
An algorithm for efficiently generating summary paragraphs using tree-adjoining grammar (2001)

We present an algorithm which improves the efficiency of a search for the optimally aggregated paragraph which summarises a flat structured input specification. We model the space of possible paraphrases of possible paragraphs as the space of sequences of compositions of a set of tree-adjoining grammar (TAG) elementary trees. Our algorithm transforms this to a set with equivalent paraphrasing power but better computational properties. Also, it identifies an explicit mapping between input propositions and their possible surface realisations.
Geometric effects of collocated monolithic support structures on separation performance in microfabricated systems (2002)

Twenty microfabricated COMOSS columns with varying dimensions were investigated in this work. Columns with different channel depth (1.6–10 μm) and width (2–4 μm) were studied; the size of collocated particles was also varied, including diamonds (5×5–11×11 μm) and their elongated and extended versions: hexagonal structures allowing greater distances between mixing nodes. Comparisons were made by plotting plate height-voltage curves for each type of column geometry using rhodamine 110, fluorescein, or small peptides as standard compounds. It was demonstrated that the efficiency of separation strongly depends on the geometry of resulting channels. An increase of distance between channel intersections (or decrease of trans-channel coupling frequency) was shown to unavoidably lead to a considerable decrease in efficiency of the microfabricated column. It was also found that low aspect ratio structures produced from positive photoresist masters were more efficient than their high aspect ratio equivalents. The highest efficiency of 620000 plates per meter was obtained with 10 μm deep channels and particles of 5.2×5.2 μm (diamonds).
Quantitation of the Dynamic Profiles of the Innate Immune Response Using Multiplex Selected Reaction Monitoring–Mass Spectrometry (2013)

The innate immune response (IIR) is a coordinated intracellular signaling network activated by the presence of pathogen-associated molecular patterns that limits pathogen spread and induces adaptive immunity. Although the precise temporal activation of the various arms of the IIR is a critical factor in the outcome of a disease, currently there are no quantitative multiplex methods for its measurement. In this study, we investigate the temporal activation pattern of the IIR in response to intracellular double-stranded RNA stimulation using a quantitative 10-plex stable isotope dilution-selected reaction monitoring-MS assay. We were able to observe rapid activation of both NF-κB and IRF3 signaling arms, with IRF3 demonstrating a transient response, whereas NF-κB underwent a delayed secondary amplification phase. Our measurements of the NF-κB-IκBα negative feedback loop indicate that about 20% of IκBα in the unstimulated cell is located within the nucleus and represents a population that is rapidly degraded in response to double-stranded RNA. Later in the time course of stimulation, the nuclear IκBα pool is repopulated first prior to its cytoplasmic accumulation. Examination of the IRF3 pathway components shows that double-stranded RNA induces initial consumption of the RIG-I PRR and the IRF3 kinase (TBK1). Stable isotope dilution-selected reaction monitoring-MS measurements after siRNA-mediated IRF3 or RelA knockdown suggests that a low nuclear threshold of NF-κB is required for inducing target gene expression, and that there is cross-inhibition of the NF-κB and IRF3 signaling arms. Finally, we were able to measure delayed noncanonical NF-κB activation by quantifying the abundance of the processed (52 kDa) NF-κB2 subunit in the nucleus. We conclude that quantitative proteomics measurement of the individual signaling arms of the IIR in response to system perturbations is significantly enabled by stable isotope dilution-selected reaction monitoring-MS-based quantification, and that this technique will reveal novel insights into the dynamics and connectivity of the IIR.
Advanced Control and Analysis of Wind and Solar Energy Systems (2011)

This research project investigates and analyses the impact of wind energy on power system networks as well as implementation of advanced controls in renewable energies of wind and solar power technologies. The analysis of wind turbine system includes small signal stability study of different turbine technologies available on the market today. Implementation of advanced control strategy for wind power is also investigated to provide improved power generation as well as mitigation of electrical and mechanical transients. The proposed advanced control strategy is a H∞ rotor side control (RSC) implementation specifically for doubly fed induction generators (DFIG), which replaces the standard RSC proportional integral (PI) control strategies. Analysis and simulation between the proposed and conventional control strategies in terms of electrical and mechanical damping are provided as well as validation in NREL’s Fatigue, Aerodynamics, Structures and Turbulence (FAST) model to verify the performance of proposed control strategy. Solar inverter technology has also been investigated in this project as part of the industrial research at CSIRO. The main driver behind the initiative is to develop an inverter control algorithm that would enable auto- islanding capabilities for a microgrid system as!well!as!to!provide stable and efficient power transfers within the whole network. In this work, genetic algorithm is applied to inverter control design and validated with computer simulation studies. The results suggested the genetic evolutionary approach for designing a controller for multiple inverter systems is an effective tool to determine control parameters as well as providing superior transient performances.
In vitro Characteristics of Heterogeneous Equine Hoof Progenitor Cell Isolates (2019)

Damage to an ectodermal-mesodermal interface like that in the equine hoof and human finger nail bed can permanently alter tissue structure and associated function. The purpose of this study was to establish and validate <i>in vitro</i> culture of primary progenitor cell isolates from the ectodermal-mesodermal tissue junction in equine hooves, the stratum internum, with and without chronic inflammation known to contribute to lifelong tissue defects. The following were evaluated in hoof stratum internum cell isolates up to 5 cell passages (P): expansion capacity by cell doublings and doubling time; plasticity with multi-lineage differentiation and colony-forming unit (CFU) frequency percentage; immunophenotype with immunocytochemistry and flow cytometry; gene expression with RT-PCR; and ultrastructure with transmission electron microscopy. The presence of keratin (K)14, 15 and K19 as well as cluster of differentiation (CD)44 and CD29 was determined <i>in situ</i> with immunohistochemistry. To confirm <i>in vivo</i> extracellular matrix (ECM) formation, cell-scaffold (polyethylene glycol/poly-L-lactic acid and tricalcium phosphate/hydroxyapatite) constructs were evaluated with scanning electron microscopy 9 weeks after implantation in athymic mice. Cultured cells had characteristic progenitor cell morphology, expansion, CFU frequency percentage and adipocytic, osteoblastic, and neurocytic differentiation capacity. CD44, CD29, K14, K15 and K19 proteins were present in native hoof stratum internum. Cultured cells also expressed K15, K19 and desmogleins 1 and 3. Gene expression of CD105, CD44, K14, K15, sex determining region Y-box 2 (SOX2) and octamer-binding transcription factor 4 (OCT4) was confirmed <i>in vitro</i>. Cultured cells had large, eccentric nuclei, elongated mitochondria, and intracellular vacuoles. Scaffold implants with cells contained fibrous ECM 9 weeks after implantation compared to little or none on acellular scaffolds. <i>In vitro</i> expansion and plasticity and <i>in vivo</i> ECM deposition of heterogeneous, immature cell isolates from the ectodermal-mesodermal tissue interface of normal and chronically inflamed hooves are typical of primary cell isolates from other adult tissues, and they appear to have both mesodermal and ectodermal qualities <i>in vitro</i>. These results establish a unique cell culture model to target preventative and restorative therapies for ectodermal-mesodermal tissue junctions.
Hearing threshold for pure tones above 20 kHz (2006)

Hearing thresholds for pure tones from 2 kHz to 28 kHz were measured. A 2AFC procedure combined with a 3-down 1-up transformed up-down method was employed to obtain threshold values that were less affected by listener’s criterion of judgment. From some listeners, threshold values of 88 dB SPL or higher were obtained for a tone at 24 kHz, whereas thresholds could not be obtained from all participants at 26 kHz and above. Furthermore, thresholds were also measured under masking by a noise low-pass filtered at 20 kHz. At frequencies above 20 kHz, the difference of threshold values between with and without the masking noise was a few decibels, indicating that the tone detection was not affected by subharmonic components that might have appeared in the lower frequency regions. The results of measurement also showed that the threshold increased rather gradually for tones from 20 to 24 kHz whereas it increased sharply from 14 to 20 kHz.