gebhart/patrepeval huggingface dataset:
Crystal structure and electronic, infrared, Raman and resonance Raman spectra of the mixed-valence, halogen-bridged, anion-chain complexes Cs2[PtII(NO2)(NH3)X2][PtIV(NO2)(NH3)X4], X = bromine or iodine (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCrystal structure and electronic, infrared, Raman and resonance Raman spectra of the mixed-valence, halogen-bridged, anion-chain complexes Cs2[PtII(NO2)(NH3)X2][PtIV(NO2)(NH3)X4], X = bromine or iodineRobin J. H. Clark, Mohamedally Kurmoo, Anita M. R. Galas, and Michael B. HursthouseCite this: Inorg. Chem. 1981, 20, 12, 4206–4212Publication Date (Print):December 1, 1981Publication History Published online1 May 2002Published inissue 1 December 1981https://pubs.acs.org/doi/10.1021/ic50226a035https://doi.org/10.1021/ic50226a035research-articleACS PublicationsRequest reuse permissionsArticle Views42Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Precopulatory behaviour of male rats: developmental aspects and dependence on female's solicitation. (1990)

Sexual communication between sex partners can involve just one sensory modality or a combination, depending upon such factors as species, habitat, and context. Ethological aspects of sexual communication has been widely documented in rodents. In rats, sexual communication between male and female varies according to the production of signals by a female that signal receptivity, proceptivity, and attractivity. However, in the laboratory experiment, such approach is often neglected. In the present study, two types of stimulus female--Lordotic and Darting--were used with the aim to examine developmental changes in precopulatory behaviour of males. Besides the dependence of the male's precopulatory repertoire on the strength of proceptive stimuli emitted by the female was studied. Male rats ranging from 30 to 175 days of age were observed under the dyadic interaction. It was found: (a) Precopulatory behaviour of the 30-day-old males was not clear-cut, the males devoted more time to social investigation of adult (Darting) female. (b) All the 40-day-old males exhibited precopulatory behaviour in the range of the repertoire displayed by adult animals. (c) Precopulatory activity of juvenile (45-day-old) as well as of adult (90-day-old) males exposed to Lordotic female was significantly lower as compared with that exhibited by males toward Darting female. (d) Copulatory readiness of males increased with the age, in fact, all animals aged from 75-135 day were able to pass from the precopulatory into the copulatory phase of sexual interaction. (e) Although the 175-day-old males exhibited pronounced precopulatory activity, they did not initiate copulations. The implications of each of these findings are discussed from the point of view of both the developmental aspects and the stimulus-response relationships. To sum up, the development of normal flow of sexual behaviour of male rats proceeds simultaneously with the development of physiological and morphological parameters. The appearance of precopulatory behaviour is less dependent on the internal (hormonal) readiness than copulatory behaviour. The connection of both phases, i.e. precopulatory and copulatory, is terminated at about Day 75, and is the key moment of sexual interaction from the point of view of reproductive success. In fact, a successful course of sexual interaction is codetermined by the intensity of behavioural stimuli and/or by the completeness of proceptive patterns provided by the female partner. It is clear that the reproductive process cannot be completed without some degree of communication. The deterioration of sexual interaction found in males aged 175 day seems to be the consequence of their absolute heterosexual abstinence.(ABSTRACT TRUNCATED AT 400 WORDS)
In Vivo Evaluation of 64Cu-Labeled Magnetic Nanoparticles as a Dual-Modality PET/MR Imaging Agent (2010)

A novel nanoparticle-based dual-modality positron emission tomograph/magnetic resonance imaging (PET/MRI) contrast agent was developed. The probe consisted of a superparamagnetic iron oxide (SPIO) core coated with PEGylated phospholipids. The chelator 1,4,7,10-tetraazacyclo-dodecane-1,4,7,10-tetraacetic acid (DOTA) was conjugated to PEG termini to allow labeling with positron-emitting (64)Cu. Radiolabeling with (64)Cu at high yield and high purity was readily achieved. The (64)Cu-SPIO probes produced strong MR and PET signals and were stable in mouse serum for 24 h at 37 degrees C. Biodistribution and in vivo PET/CT imaging studies of the probes showed a circulation half-life of 143 min and high initial blood retention with moderate liver uptake, making them an attractive contrast agent for disease studies.
A Systems Architectural Model for Man-Packable/Operable Intelligence, Surveillance, and Reconnaissance Mini/Micro Aerial Vehicles (2005)

With the increase in both technology push and operational pull of mini/micro aerial vehicles (MAVs) within DoD organizations, an understanding of their interactions and capabilities is necessary. Many MAVs have already been developed for a specific usage and much speculation has been made on their future uses. Despite the growth of MAVs, there is currently no overarching systems architecture which would envelop and guide the DoD's MAV development efforts. The goal of this thesis is to apply sound systems engineering principals to develop a MAV architectural model describing their use in three separate but closely related mission areas: Over-the-Hill-Reconnaissance, Battle Damage Information, and Local Area Defense. This thesis focuses on single-man packable/operable MAVs utilized by small ground units synonymous with special operations forces. The three mission areas are combined to define a single overarching Intelligence, Surveillance, and Reconnaissance (ISR) MAV architecture. This architecture focuses on the current state of ISR MAVs and provides a baseline current capability. From this architecture, areas of interest relating to MAVs and their use in the DoD are discussed, focusing on enhancing both current and future capabilities of MAVs.
Pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) deficiency attenuates the long-term negative effects of a high-saturated fat diet (2009)

The hypothesis that PDHK4 (pyruvate dehydrogenase kinase isoenzyme 4) has potential as a target for the treatment of type 2 diabetes was tested by feeding wild-type and PDHK4 knockout mice a high saturated fat diet that induces hyperglycemia, hyperinsulinaemia, glucose intolerance, hepatic steatosis and obesity. Previous studies have shown that PDHK4 deficiency lowers blood glucose by limiting the supply of three carbon gluconeogenic substrates to the liver. There is concern, however, that the increase in glucose oxidation caused by less inhibition of the pyruvate dehydrogenase complex by phosphorylation will inhibit fatty acid oxidation, promote ectopic fat accumulation and worsen insulin sensitivity. This was examined by feeding wild-type and PDHK4 knockout mice a high saturated fat diet for 8 months. Fasting blood glucose levels increased gradually in both groups but remained significantly lower in the PDHK4 knockout mice. Hyperinsulinaemia developed in both groups, but glucose tolerance was better and body weight was lower in the PDHK4 knockout mice. At termination, less fat was present in the liver and skeletal muscle of the PDHK4 knockout mice. Higher amounts of PGC-1alpha [PPARgamma (peroxisome proliferator-activated receptor gamma) coactivator 1alpha] and PPARalpha and lower amounts of fatty acid synthase and acetyl-CoA carboxylase isoenzyme 1 were present in the liver of the PDHK4 knockout mice. These findings suggest PDHK4 deficiency creates conditions that alter upstream signalling components involved in the regulation of lipid metabolism. The findings support the hypothesis that PDHK4 is a viable target for the treatment of type 2 diabetes.
DAMAGE-FUNCTION ANALYSIS OF NEUTRON-ENERGY AND SPECTRUM EFFECTS UPON THE RADIATION EMBRITTLEMENT OF STEELS. (1969)

The report presents the results of a new, comprehensive set of experimental data conforming to the irradiation conditions of the derived damage function (material, temperature, and fluence). The results of this experiment are discussed in terms of their establishing the validity of the damage function. Averaged values of the damage function are tabulated for a typical reactor physics calculation energy group structure, and their application to two different spectra is described. Finally, the damage-function fluences required to cause a 200F Delta-TT in A302-B steel are presented for many different reactor locations. For each of the spectra involved, the upper and lower energy limits of significantly damaging neutrons are given, and some detail is also provided regarding the contribution of subgroups within the overall energy spectrum. (Author)
Model predictive error : how it arises and how it can be accommodated (2008)

This paper presents a brief overview of the means by which the potential error associated with predictions made by a calibrated model can be estimated. This is important both in its own right, and as a means of optimizing the acquisition of future data to reduce this potential error. It is shown that there are two major contributors to the predictive error of a calibrated model, referred to herein as the null space and solution space contributions. The first is an outcome of the fact that system properties can only be estimated in broad detail through the calibration process; to the extent that a prediction is sensitive to finer detail than this, its potential for error is not reduced through model calibration. The second is an outcome of the fact that even estimates of broad-scale system properties carry some error, this resulting from the fact that they are estimated on the basis of data contaminated by (measurement and structural) noise. Methodologies for computation of these two terms are presented; reference is made to publicly available software through which these methodologies are implemented.
Calcium‐dependent regulation of the enkephalin phenotype by neuronal activity during early ontogeny (1991)

Genetic components of the neuronal phenotype are regulated by epigenetic factors--trophic molecules and neuronal activity--during neurodifferentiation. Developing neurons in dissociated cultures of embryonic mouse spinal cord show spontaneous electrical activity after one week in culture. We now report that the blockade of this spontaneous electrical activity for two days with tetrodotoxin (TTX) causes virtually complete down-regulation of preproenkephalin A gene transcripts in embryonic spinal cord cultures. This TTX-induced down-regulation is fully reversed upon reinitiation of neuronal activity (removal of TTX from cultures). This reversible, tetrodotoxin-induced down-regulation of enkephalin mRNA is confined to a restricted period of early neurodevelopment (days 7 to 21 in culture). Since depolarization triggers calcium entry through voltage-activated calcium channels, we have investigated the involvement of calcium in the mechanism of this activity- and age-dependent regulation of preproenkephalin A expression. The selective activation of the L-type of voltage-sensitive calcium channels by a dihydropyridine derivative [(+) 202-791] prevented this TTX-induced down-regulation without reducing methionine enkephalin secretion. This effect was observed only when the drug was applied to electrically active cultures, prior to the addition of TTX. Simultaneous application of (+) 202-791 and TTX, or pretreatment with TTX, failed to prevent TTX-induced down-regulation. Thus, activity-dependent phenotypic plasticity of met-enkephalinergic neurons in spinal cord is: 1) maximum at an early age of neuronal development (less than 10 days in culture) and becomes less apparent in old cultures (greater than 30 days); 2) reversible throughout; and 3) mediated by calcium entry through L-type channels.
Association between dislocation, impingement, and articular geometry in retrieved acetabular polyethylene cups (2007)

We used a novel analysis technique and retrieved acetabular polyethylene liners to investigate relationships between impingement damage, dislocation history, and polyethylene liner geometry. Forty-eight polyethylene liners with neutral rim elevation were visually assessed for peripheral rim damage consistent with impingement between the liner rim and femoral component. Liner articular geometry was measured using a digital stylus, and the geometric relationships between the liner rim and center of the femoral head were characterized by lip height, head center inset, and head penetration into the polyethylene liner. Thirteen (27%) retrieved liners had rim impingement damage and 12 (25%) had a history of dislocation. The proportion of liners with impingement was not significantly different among dislocated and stable liners. Lip height, head center inset, and head penetration were not significantly different between liners with and without impingement damage. Dislocated liners had a significantly shorter head center inset, with significantly less head penetration because of shorter functional duration. Designing polyethylene liners with a sufficiently deep articular surface that exceeds 0.95 mm may prove beneficial for decreasing the prevalence of early dislocation, independent of impingement damage.
Purification and Characterization of Cytosolic Serine Hydroxymethyltransferase fromEuglena gracilisz (1991)

Journal Article Purification and Characterization of Cytosolic Serine Hydroxymethyltransferase from Euglena gracilis z Get access Masako Sakamoto, Masako Sakamoto Shitennōji International Buddhist University, Habikino, Osaka 583, Japan Search for other works by this author on: Oxford Academic Google Scholar Tsutomu Masuda, Tsutomu Masuda Shitennōji International Buddhist University, Habikino, Osaka 583, Japan Search for other works by this author on: Oxford Academic Google Scholar Yukio Yanagimoto, Yukio Yanagimoto Shitennōji International Buddhist University, Habikino, Osaka 583, Japan Search for other works by this author on: Oxford Academic Google Scholar Yoshihisa Nakano, Yoshihisa Nakano Department of Agriculture, University of Osaka Prefecture, Sakai, Osaka 591, Japan Search for other works by this author on: Oxford Academic Google Scholar Shozaburo Kitaoka Shozaburo Kitaoka Department of Agriculture, University of Osaka Prefecture, Sakai, Osaka 591, Japan Search for other works by this author on: Oxford Academic Google Scholar Agricultural and Biological Chemistry, Volume 55, Issue 9, 1 September 1991, Pages 2243–2249, https://doi.org/10.1080/00021369.1991.10870946 Published: 01 September 1991 Article history Received: 08 February 1991 Published: 01 September 1991
Human nucleosomes: special role of CG dinucleotides and Alu-nucleosomes (2011)

Although the CG dinucleotides are dominant, other elements of the standard nucleosome positioning pattern are present in the human genome as well.The positional autocorrelation analysis of the human genome demonstrates that the CG dinucleotide is, indeed, one visible element of the human nucleosome positioning pattern, which appears both in Alu sequences and in sequences without repeats. The dominant role that CG dinucleotides play in organizing human chromatin is to indicate the involvement of human nucleosomes in tuning the regulation of gene expression and chromatin structure, which is very likely due to cytosine-methylation/-demethylation in CG dinucleotides contained in the human nucleosomes. This is further confirmed by the positions of CG-periodical nucleosomes on Alu sequences. Alu repeats appear as monomers, dimers and trimers, harboring two to six nucleosomes in a run. Considering the exceptional role CG dinucleotides play in the nucleosome positioning, we hypothesize that Alu-nucleosomes, especially, those that form tightly positioned runs, could serve as "anchors" in organizing the chromatin in human cells.
Masakatsu Fujita, Philosophie und Religion beim jungen Hege. Hegel-Studien Beiheft 26, Bonn, Bouvier Verlag Herbert Grundmann, 1985, pp. 198, clothback. (1985)

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Investigation of a Passive Thermal Management System for Lithium-Ion Capacitors (2019)

Lithium-ion capacitors (LiCs) have emerged as a promising technology for automotive applications due to the solution offered by their power density, high voltage operation and their excellent durability (more than 2 million cycles). Nevertheless, the reliability of LiCs can be drastically affected by overheating issues which raise the importance of thermal management. Nowadays, active cooling is employed to keep the battery systems temperature in range. However, due to the bulkiness and weight of the existing active cooling systems, latent heat thermal energy storage through the use of phase change materials (PCMs), represents an attractive way. In this paper, paraffin is investigated experimentally and simulated as a PCM cooling solution for the thermal management of a dual-LiC module. Moreover, since paraffin presents a low thermal conductivity characteristic, an additional component such as aluminium mesh grid is inserted to the system to solve the low conductivity issue. Results show good performance of the Al-PCM on the battery thermal management for both ESSs with a relatively lower temperature. The Al-PCM combination was able is lower the temperature to 36 °C compared to natural convection (46 °C).
Mouse orthotopic models for bladder cancer research (2009)

Bladder cancer is a common malignancy in the urinary tract. Despite different therapeutic options, recurrence and progression of urothelial carcinoma after treatment is not uncommon. Novel therapeutic options of bladder cancer are urgently needed. The preclinical evaluation of new treatments requires an animal tumour model that mimics the human counterpart. To date, various animal orthotopic bladder cancer models have been described, but the reported rate of tumour 'take' is 30-100%. The establishment of reliable and reproducible animal models remains an ongoing challenge. We review different kinds of mouse models of orthotopic bladder cancer used in urothelial cancer studies, the methods of implantation, and the reported rate of tumour take. Significant progress has been made recently in noninvasive small animal-imaging in tumour models. It is now possible for researchers to investigate the effects of studied agents by monitoring of in vivo tumour growth directly and noninvasively, as well as measuring a wide range of tumour-related variables in small animals. We summarize the recent development in small-animal imaging for tumour detection and quantification.
Functional Consequence of Substitutions at Residue 171 in Human Galactose-1-phosphate Uridylyltransferase (2000)

Impairment of the human enzyme galactose-1-phosphate uridylyltransferase (hGALT) results in the potentially lethal disorder classic galactosemia. Although a variety of naturally occurring mutations have been identified in patient alleles, few have been well characterized. We have explored the functional significance of a common patient mutation, F171S, using a strategy of conservative substitution at the defined residue followed by expression of the wild-type and, alternatively, substituted proteins in a null-background strain of yeast. As expected from patient studies, the F171S-hGALT protein demonstrated <0.1% wild-type levels of activity, although two of three conservatively substituted moieties, F171L- and F171Y-hGALT, demonstrated approximately 10% and approximately 4% activity, respectively. The third protein, F171W, demonstrated severely reduced abundance, precluding further study. Detailed kinetic analyses of purified wild-type, F171L- and F171Y-hGALT enzymes, coupled with homology modeling of these proteins, enabled us to suggest that the effects of these substitutions resulted largely from altering the position of a catalytically important residue, Gln-188, and secondarily, by altering the subunit interface and perturbing hexose binding to the uridylylated enzyme. These results not only provide insight into the functional impact of a single common patient allele and offer a paradigm for similar studies of other clinically or biochemically important residues, but they further help to elucidate activity of the wild-type human GALT enzyme.
ChemInform Abstract: The 573 K and 773 K Isothermal Sections of the Phase Diagram of the Pr—Ni—Ti Ternary System. (2001)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A random wrapping encryption method (2014)

Today the quick development of computers and networks not only enriches our everyday life, but also provides us with a convenient living environment. However, hackers are everywhere in the world. Hence, our sensitive data need to be securely protected. Currently, AES and DES as the most widely used block ciphering mechanisms are popularly employed to encrypt important data. But DES was publicly cracked several years ago. On the other hand, due to the fast computer processing speed and processing power, currently no one dare to say that AES is still secure. It may be cracked someday. Therefore, in this paper, we propose a secure encryption method, called the Random Wrapping Encryption Method (RWEM for short), which is developed by employing information of current time as a part of the parameters to wrap up ciphertext in its encryption process. If a file is encrypted at different time points, the content and the length of the wrapped ciphertext file will not be the same. Thus, it is hard for hackers to analyze and crack the ciphertext. We also analyze the security of the DES, AES and RWEM, and explain why the RWEM can effectively protect some specific attacks, and why it is more secure than the DES and AES.
<title>Alignment of erythrocytes in nematic liquid crystal media with different dielectric anisotropy</title> (1998)

The alignment effect of erythrocytes in liquid crystal media with different optical and dielectric anisotropies has been investigated. The effect has been compared with the Froelich interaction.
Perioperative Family Updates Reduce Anxiety and Improve Satisfaction: A Randomized Controlled Trial (2021)

Anxiety and satisfaction with perioperative updates were significantly improved by additional perioperative updates. These findings indicate that updating families during significant standardized strategic perioperative events can reduce the anxiety of loved ones and are preferred by most families.