gebhart/patrepeval huggingface dataset:
Context-based media adaptation in pervasive computing (2002)

In pervasive computing applications, computer embedded devices are used to perform control tasks and access the Internet or other information sources. However, most content of current information sources was designed with desktop computers and high-speed network connections in mind. They contain rich media data, which are not suitable for those pervasive devices with limited capabilities. Moreover, for different user preference and application scenarios, not all of the data are relevant and critical to the application. Context-based media adaptation is mainly concerned with selecting different qualities of single media types or selecting different media types, and then delivering information to different context. Some related issues for building a general context-based media adaptation framework are discussed. These issues include context description and exchange schemes, adaptable model for managing and manipulating multimedia content, adaptation techniques and architectural issues.
High Throughput Assays for Analyzing Transcription Factors (2006)

Transcription factors are a group of proteins that modulate the expression of genes involved in many biological processes, such as cell growth and differentiation. Alterations in transcription factor function are associated with many human diseases, and therefore these proteins are attractive potential drug targets. A key issue in the development of such therapeutics is the generation of effective tools that can be used for high throughput discovery of the critical transcription factors involved in human diseases, and the measurement of their activities in a variety of disease or compound-treated samples. Here, a number of innovative arrays and 96-well format assays for profiling and measuring the activities of transcription factors will be discussed.
Fractal Geometry of Airway Remodeling in Human Asthma (2005)

Fractal analysis is a simple and useful technique for quantifying the chronic structural changes of airway remodeling in asthma.
Oxygen Uptake Rate Soft-Sensing via Dynamic kLa Computation: Cell Volume and Metabolic Transition Prediction in Mammalian Bioprocesses (2019)

In aerobic cell cultivation processes, dissolved oxygen is a key process parameter, and an optimal oxygen supply has to be ensured for proper process performance. To achieve optimal growth and/or product formation, the rate of oxygen transfer has to be in right balance with the consumption by cells. In this study, a 15 L mammalian cell culture bioreactor was characterized with respect to kLa under varying process conditions. The resulting dynamic kLa description combined with functions for the calculation of oxygen concentrations under prevailing process conditions led to an easy-to-apply model, that allows real-time calculation of the oxygen uptake rate (OUR) throughout the bioprocess without off-gas analyzers. Subsequently, the established OUR soft-sensor was applied in a series of 13 CHO fed-batch cultivations. The OUR was found to be directly associated with the amount of viable biomass in the system, and deploying of cell volumes instead of cell counts led to higher correlations. A two-segment linear model predicted the viable biomass in the system sufficiently. The segmented model was necessary due to a metabolic transition in which the specific consumption of oxygen changed. The aspartate to glutamate ratio was identified as an indicator of this metabolic shift. The detection of such transitions is enabled by a combination of the presented dynamic OUR method with another state-of-the-art viable biomass soft-sensor. In conclusion, this hyphenated technique is a robust and powerful tool for advanced bioprocess monitoring and control based exclusively on bioreactor characteristics.
Theoretical analysis of the electrically excited KrF laser (1978)

The results obtained from a comprehensive theoretical model for an electrically excited laser are compared with experimental data obtained from a large-volume KrF laser device, excited by an e−-beam only, or with enhancement from an electric discharge.
Comparative Evaluation of Certain Excipients and their Binary Blends for Direct Compression Oxytetracycline Hydrochloride Tablets (1985)

Five direct compression excipients as well as their binary blends in ratios of 1:1, 1:3 and 3:1 were comparatively evaluated to compress oxytetracycline hydrochloride into tablets. With respect to the mechanical properties of the produced tablets, Avicel PH101, Celutab and STAR-x1500 in this order, were the most suitable single excipients for the production. The results showed that the incorporation of a second excipient in the formulation changes the physical standards of the produced antibiotic tablets. It was found that not only the type of the incorporated excipient is effective but also, its concentration in the formula. The investigation proved that Avicel/STAR-x1500 blends in all different ratios followed by some blends of celutab with Avicel or STAR-x1500 were the best blended excipients to produce satisfactory antibiotic tablets.
Two-dimensional magnetic susceptibility mapping of long objects by magnetic resonance imaging (2014)

Magnetic susceptibility is the inherent property of materials. Magnetic resonance imaging as a kind of non-invasive testing technique may measure the magnetic field distortion induced by the imaging object and consequently calculate its magnetic susceptibility distribution. Conventionally, magnetic susceptibility mapping is performed in three-dimensional mode with the requirement of multi-slice scanning. In the condition of long objects that have uniform distribution along one direction, two-dimensional phase image of the cross section might be enough to estimate the susceptibility. In this study, we adjust susceptibility mapping algorithm into a two-dimensional mode and evaluate the possibility of using a single-slice image to estimate the magnetic susceptibility. Simulation was performed to validate the algorithm in both ideal and noise-imposed conditions. MRI experiment was performed by using copper, graphite and iron oxide at different concentrations. The results suggest that it is possible to measure the susceptibility of a long object by a two-dimensional image.
Insulin Mutation Screening in 1,044 Patients With Diabetes (2007)

We conclude that INS mutations are the second most common cause of PND and a rare cause of MODY. Insulin gene mutation screening is recommended for all diabetic patients diagnosed before 1 year of age.
ChemInform Abstract: STERICALLY CONTROLLED SYNTHESES OF OPTICALLY ACTIVE ORGANIC COMPOUNDS PART 21, THE TEMPERATURE DEPENDENCE OF HYDROGENOLYTIC ASYMMETRIC TRANSAMINATION BETWEEN OPTICALLY ACTIVE PHENYLGLYCINE AND ALPHA‐KETO ACIDS (1973)

Abstract Die Hydrierung der in Lösungen von (R)‐Phenylglycin (I) und der Ketosäuren (II) (Molverhältnis 1:10) in lm wäßrigem NaOH vorliegenden Kondensationsprodukte (III) an Pd/Cbei lO‐70°C liefert über die Stufe der Iminodicaroonsäuren (IV) neben Phenylessigsäure (V) bevorzugt die (R)‐Aminosäuren (VI).
Protocollagen Proline Hydroxylase from Ascaris lumbricoides (1969)

An enzyme was found in the muscle layers of Ascaris lumbricoides which was similar to the protocollagen proline hydroxylase found in chick embryos and other vertebrates in that it synthesized 14C-hydroxyprolme when incubated with 14C-proline-labeled protocollagen from chick cartilage.The Ascaris enzyme was also similar in that it required atmospheric oxygen, a-ketoglutarate, iron, and ascorbate in order to synthesize 14C-hydroxyproline.A further similarity between the Ascaris hydroxylase and the one in chick embryos was that preparations of proline-labeled protocollagen from the cuticle of Ascaris served as substrates only after they were boiled.The Ascaris hydroxylase differed from the chick embryo enzyme in that it was partially inhibited by incubation in normal atmospheric air, and the rate of the reaction increased by about 50% as the oxygen content of the gas phase was reduced to 1%.The K, for cY-ketoglutarate for the Ascaris enzyme was about 4 X lo-4 M, or about loo-fold greater than the K, for oc-ketoglutarate with the chick embryo enzyme.A further difference was that the Ascaris enzyme was not inhibited by poly-L-proline form II which competitively inhibits the chick embryo enzyme.Two distinct types of collagen are present in Ascuris lumbricoides.The collagen isolated from the cuticle differs from collagen found in vertebrates in that it has a low content of hydroxyproline, a high content of proiine, and essentially no hydroxylysine(1, 2).Also, physical measurements (2-4) and enzymatic studies (5) indicate that the molecule has an unusual conformation.
Serum Differentially Alters the Antifungal Properties of Echinocandin Drugs (2007)

Antifungal efficacies of the echinocandin drugs caspofungin, micafungin, and anidulafungin were reduced significantly in the presence of 50% human serum, which yielded nearly equivalent MICs or minimum effective concentrations against diverse Candida spp. and Aspergillus spp. Consistent with a direct drug interaction, serum decreased the sensitivity of glucan synthase to echinocandin drugs.
CellFlow: A Parallel Rendering Scheme for Distributed Memory Architectures. (1995)

CellFlow is an animation system that exploits frame coherency to implement a lookahead scheme of object dataflow. The implementation of this scheme uses the communication features of modern scalable multicomputers to achieve good speedup by means of latency hiding. We demonstrate the performance of our approach in the field of volume rendering by implementing incremental rotation of the volumetric object about its center. The main advantages of the algorithm are: its simplicity, its optimal embedding in popular network topologies, and minimal, congestion-free communication among processors. Results are shown for implementation on the Cray T3D, a distributed memory 3D torus architecture. Computation and communication load balancing issues among processors are also addressed. 1. Introduction Medical data obtained from MRI (magnetic resonance imaging) and CT-scanners (computed tomography) act as good sources for volume visualization [5][9][11] applications. This technique is also applie...
Distributed Ambient SWIPT System (2022)

This article demonstrates the great utility of distributed approaches in backscattered communication systems. Initially, the distributed network, composed of backscatter transmitters and receivers is demonstrated. Then this is combined with an RF-DC converter and a fully Simultaneous Wireless Information and Power Transfer (SWIPT) is described in detail. Combining these two technologies demonstrates that it is possible to reuse a city’s 5G network as a gateway for smart city monitoring without increasing the current radiation level or energy consumption.
Applying machine learning classifiers to dynamic Android malware detection at scale (2013)

The widespread adoption and contextually sensitive nature of smartphone devices has increased concerns over smartphone malware. Machine learning classifiers are a current method for detecting malicious applications on smartphone systems. This paper presents the evaluation of a number of existing classifiers, using a dataset containing thousands of real (i.e. not synthetic) applications. We also present our STREAM framework, which was developed to enable rapid large-scale validation of mobile malware machine learning classifiers.
Special Section Guest Editorial: Pioneer in Biomedical Optics: Introduction to the Special Section in Honor of Steven L. Jacques (2018)

This guest editorial introduces the special section honoring Prof. Steven L. Jacques.
Automated analysis of feeding behavior in small animals (2002)

Discusses the implementation of an automated apparatus for recording and quantifying food choice behavior by small animals. A computer controls the apparatus by positioning a video camera over each one of twelve petri dishes. When the camera is in position, an image of the underlying dish is captured and the digitized image is returned to the computer for further processing. Within the computer a digital image processing procedure analyzes and quantifies the observed behavior.
Redifferentiation of Cancer Cells: Bestatin, Estradiol, and Prostaglandin D2 (1985)

The induction of redifferentiation of cancer cells was studied. This was achievable with bestatin, especially in combination with sex hormones or prostaglandin D2, in murine undifferentiated mammary adenocarcinoma cells in vitro. Prostaglandin D2 also exerted a similar redifferentiating effect on M1 murine leukemia cells and a consecutive bestatin-hormone regimen was effective in endocrine tumors in man. Cancer redifferentiation may one day be developed into a clinical technique.
Adaptation and Antibiotic Tolerance of Anaerobic Burkholderia pseudomallei (2011)

The Gram-negative bacterium Burkholderia pseudomallei is the etiological agent of melioidosis and is remarkably resistant to most classes of antibacterials. Even after months of treatment with antibacterials that are relatively effective in vitro, there is a high rate of treatment failure, indicating that this pathogen alters its patterns of antibacterial susceptibility in response to cues encountered in the host. The pathology of melioidosis indicates that B. pseudomallei encounters host microenvironments that limit aerobic respiration, including the lack of oxygen found in abscesses and in the presence of nitric oxide produced by macrophages. We investigated whether B. pseudomallei could survive in a nonreplicating, oxygen-deprived state and determined if this physiological state was tolerant of conventional antibacterials. B. pseudomallei survived initial anaerobiosis, especially under moderately acidic conditions similar to those found in abscesses. Microarray expression profiling indicated a major shift in the physiological state of hypoxic B. pseudomallei, including induction of a variety of typical anaerobic-environment-responsive genes and genes that appear specific to anaerobic B. pseudomallei. Interestingly, anaerobic B. pseudomallei was unaffected by antibacterials typically used in therapy. However, it was exquisitely sensitive to drugs used against anaerobic pathogens. After several weeks of anaerobic culture, a significant loss of viability was observed. However, a stable subpopulation that maintained complete viability for at least 1 year was established. Thus, during the course of human infection, if a minor subpopulation of bacteria inhabited an oxygen-restricted environment, it might be indifferent to traditional therapy but susceptible to antibiotics frequently used to treat anaerobic infections.
Wavelength selective WDM modulator with high-Q ring resonators in deeply etched InP/InGaAsP waveguides (2004)

Electro-refractive InP/InGaAsP ring-resonators with quality factors of up to 20000 are demonstrated. A novel modified MMI-coupler is used to provide reproducible low coupling to the access waveguide. We demonstrate modulation and the first link experiments.
High-performance and high-temperature continuous-wave-operation 1300 nm InGaAsN quantum well lasers by organometallic vapor phase epitaxy (2003)

Comtinuous-wave (cw) operation of organometallic vapor phase epitaxy-grown In0.4Ga0.6As0.995N0.005 quantum well (QW) lasers has been realized, at a room-temperature near-threshold emission wavelength of 1.295 μm, with a threshold-current density of 220 A/cm2 for 2000 μm cavity-length (Lcav) devices. A threshold current density of only 615 A/cm2 was achieved for cw operation at a temperature of 100 °C, with an emission wavelength of 1.331 μm. A maximum cw-output power of 1.8 W was obtained for InGaAsN QW lasers with cavity lengths of 1000 and 2000 μm, at a heat-sink temperature of 20 °C.
Use of all-reflecting objective for interferometric coherent anti-Stokes Raman scattering microscopy (2011)

Reflecting objective is compared to refracting one in an interferometric coherent anti-Stokes Raman scattering microscopy. We find that non-dispersive characteristic of reflection makes the reflecting objective more suitable for interferometric imaging than the refracting one.
Efficacy and tolerability of vildagliptin in drug‐naïve patients with type 2 diabetes and mild hyperglycaemia* (2008)

In drug-naïve patients with mild hyperglycaemia, relative to placebo, 52-week treatment with vildagliptin 50 mg q.d. significantly decreases A1C, FPG and PPG and improves beta-cell function without weight gain or hypoglycaemia.
An Experimental Study of Prolonged Left Heart Bypass Without Thoracotomy (1962)

Hall, David P. M.D.; Moreno, Juan R. M.D.; Dennis, Clarence M.D., Ph.D.; Senning, Åke M.D. Author Information
A convolutional neural network approach for face verification (2014)

In this paper, we present a convolutional neural network (CNN) approach for the face verification task. We propose a “Siamese” architecture of two CNNs, with each CNN reduced to only four layers by fusing convolutional and subsampling layers. Network training is performed using the stochastic gradient descent algorithm with annealed global learning rate. Generalization ability of network is investigated via unique pairing of face images, and testing is done on AT&T face database. Experimental work shows that the proposed CNN system can classify a pair of 46×46 pixel face images in 0.6 milliseconds, which is significantly faster compared to equivalent network architecture with cascade of convolutional and subsampling layers. The verification accuracy achieved is 3.33% EER (equal error rate). Learning converges within 20 epochs, and the proposed technique can verify a test subject unseen in training. This work shows the viability of the “Siamese” CNN for face verification applications, and further improvements to the architecture are under construction to enhance its performance.
Coexistence of the (23 × √3) Au(111) Reconstruction and a Striped Phase Self-Assembled Monolayer (2002)

We have studied the effect of adsorption of a low-density alkanethiol monolayer on the state of the Au(111) reconstruction. It is commonly believed that the substrate deconstructs following formation of a thiolate self-assembled monolayer, but our results suggest this is not always the case. Helium diffraction from 1-decanethiol and 1-octanethiol striped phase monolayers is exploited to establish the surface nearest-neighbor spacing and to illustrate a unit cell corresponding to the long dimension of the (23 × √3) reconstruction. Using our observed 0.198 Å-1 peak spacing and the (11.5 × √3) unit cell reported in the literature, we measure a substrate nearest-neighbor spacing of 2.76 Å along the [11̄0] direction, which represents the atomic spacing of the uniaxially compressed, reconstructed gold surface. Moreover, 1/2-order peaks in the diffraction from decanethiol/Au(111) demonstrate a distinction between neighboring thiolate dimers. These peaks are not observed for the octanethiol/Au(111) system. Therefore, the 1/2-order peaks are not an inherent characteristic of alkanethiol SAMs. The most likely explanation for these peaks is a reconstructed substrate. Complementary scanning tunneling microscopy data are also presented that show persistence of the reconstruction during growth of a decanethiol striped phase monolayer and no evidence for vacancy islands typically associated with deconstruction or alternate reconstructions. Our model involving a still-reconstructed substrate is consistent with all of the available data, while alternative models fail to explain the results presented in this article.
TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury (2005)

Cold hyperalgesia is a well-documented symptom of inflammatory and neuropathic pain; however, the underlying mechanisms of this enhanced sensitivity to cold are poorly understood. A subset of transient receptor potential (TRP) channels mediates thermosensation and is expressed in sensory tissues, such as nociceptors and skin. Here we report that the pharmacological blockade of TRPA1 in primary sensory neurons reversed cold hyperalgesia caused by inflammation and nerve injury. Inflammation and nerve injury increased TRPA1, but not TRPM8, expression in tyrosine kinase A-expressing dorsal root ganglion (DRG) neurons. Intrathecal administration of anti-nerve growth factor (anti-NGF), p38 MAPK inhibitor, or TRPA1 antisense oligodeoxynucleotide decreased the induction of TRPA1 and suppressed inflammation-and nerve injury-induced cold hyperalgesia. Conversely, intrathecal injection of NGF, but not glial cell line-derived neurotrophic factor, increased TRPA1 in DRG neurons through the p38 MAPK pathway. Together, these results demonstrate that an NGF-induced TRPA1 increase in sensory neurons via p38 activation is necessary for cold hyperalgesia. Thus, blocking TRPA1 in sensory neurons might provide a fruitful strategy for treating cold hyperalgesia caused by inflammation and nerve damage.
Glass Surface Reheat in Pressware Formation (1969)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation R. C. Steere; Glass Surface Reheat in Pressware Formation. Journal of Applied Physics 1 August 1969; 40 (9): 3884–3885. https://doi.org/10.1063/1.1658304 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioJournal of Applied Physics Search Advanced Search |Citation Search
An architecture for the coordination of system management services (2004)

Today, system management services are implemented by dedicated subsystems, built using proprietary system management components. These subsystems are customized to automate their operations to the extent feasible. This model has been successful in dedicated enterprise environments, but there are opportunities to broaden the scope of these services to multicustomer utility computing environments while reducing the costs of providing these services. A new model suitable for utility computing is being developed to address these opportunities. This model features several new elements: (1) a repository to represent the state of the remotely managed components and of the services that manage them, (2) a repository of policies and operational constraints, and (3) a set of meta-management services that use existing management services to analyze, construct, and safely execute a complex set of management tasks on remote systems. The meta-management services manage the system management services provided by the utility—;they guide and modify the behavior of the services, often as a result of the collective analysis of the state of one or more services. In this paper, we describe requirements and behaviors of such meta-management services and the architecture to provide them. We focus on the components of this architecture that enable and provide effective meta-management services in a utility environment.