gebhart/patrepeval huggingface dataset:
Growth and properties III&#x2013;V films and multilayered structures on fianite substrates and buffer layers (2010)

The opportunity of the use Si and GaAs with single and double buffer layers and YSZ substrates for III-V(GaAs, InAs, GaSb, InGaAs, AlGaAs, GaN, AlN) epitaxy by a MOCVD method is investigated. The technology of single YSZ and double (YSZ on porous material) buffer layers preparation on Si and GaAs substrates is developed. By using porous substrate, we improved structure and morphology of YSZ buffer layers. It is shown, that III-V films received on YSZ substrates and buffer layers have single crystalline structure, good morphology and high electrophysical and photoluminescent properties. The use of the two-layer buffer in comparison with the single YSZ buffer improves adhesion of III-V films and raises its structural and electric homogeneity.
T4 Phage Gene 32 Protein as a Candidate Organizing Factor for the Deoxyribonucleoside Triphosphate Synthetase Complex (1996)

After T4 bacteriophage infection of Escherichia coli, the enzymes of deoxyribonucleoside triphosphate biosynthesis form a multienzyme complex that we call T4 deoxyribonucleoside triphosphate (dNTP) synthetase. At least eight phage-coded enzymes and two enzymes of host origin are found in this 1.5-mDa complex. The complex may shuttle dNTPs to DNA replication sites, because replication draws from small pools, which are probably highly localized. Several specific protein-protein contacts within the complex are described in this paper. We have studied protein-protein interactions in the complex by immobilizing individual enzymes and identifying radiolabeled T4 proteins that are retained by columns of these respective affinity ligands. Elsewhere we have described interactions involving three T4 enzymes found in the complex. In this paper we describe similar analysis of five more proteins: dihydrofolate reductase, dCTPase-dUTPase, deoxyribonucleoside monophosphokinase, ribonucleotide reductase, and E. coli nucleoside diphosphokinase,. All eight proteins analyzed to date retain single-strand DNA-binding protein (gp32), the product of T4 gene 32. At least one T4 protein, thymidylate synthase, binds directly to gp32, as shown by affinity chromatographic analysis of the two purified proteins. Among its several roles, gp32 stabilizes single-strand template DNA ahead of a replicating DNA polymerase. Our data suggest a model in which dNTP synthetase complexes, probably more than one per growing DNA chain, are drawn to replication forks via their affinity for gp32 and hence are localized so as to produce dNTPs at their sites of utilization, immediately ahead of growing DNA 3' termini.
Sensitivity of Soil Manganese Oxides (2001)

The examination of soils by x‐ray absorption near‐edge structure (XANES) spectroscopy can provide valuable clues for determining the structure and composition of Mn oxides. XANES experiments can be conducted at ambient temperatures using field‐moist samples. This feature is attractive in the study of soil Mn because of the well‐documented effects of sample drying on reactivity. The present study was undertaken to determine whether the analysis of field‐moist soils by XANES spectroscopy has an effect on the oxidation state of the Mn. Repeated scans were taken on the same spot using seven medium‐ to high‐Mn soils. In all 10 experiments with untreated soils, the main absorption edge dropped in relative energy in successive scans, indicating reduction of Mn. The change in eV was as high as 1.7 eV after 150 min of exposure time. After a series of scans showing reduction, small movement of the sample in the x‐ray beam and reexamination showed no reduction, indicating that the effect was limited to the x‐ray spot. Modeling the change with Mn(II) was successful and showed increases in reduced Mn between 6 and 20% after three to five repeated scans. The slopes of eV change vs. exposure time were remarkably similar in most experiments, even with large differences in the density of photons between runs. Comparisons of initial moist scans with those of recently air‐dried samples found little difference, suggesting minimal reduction in a single XANES scan under our experimental conditions.
Classification of Suicide Attempts through a Machine Learning Algorithm Based on Multiple Systemic Psychiatric Scales (2017)

Classification and prediction of suicide attempts in high-risk groups is important for preventing suicide. The purpose of this study was to investigate whether the information from multiple clinical scales has classification power for identifying actual suicide attempts. Patients with depression and anxiety disorders (<i>N</i> = 573) were included, and each participant completed 31 self-report psychiatric scales and questionnaires about their history of suicide attempts. We then trained an artificial neural network classifier with 41 variables (31 psychiatric scales and 10 sociodemographic elements) and ranked the contribution of each variable for the classification of suicide attempts. To evaluate the clinical applicability of our model, we measured classification performance with top-ranked predictors. Our model had an overall accuracy of 93.7% in 1-month, 90.8% in 1-year, and 87.4% in lifetime suicide attempts detection. The area under the receiver operating characteristic curve (AUROC) was the highest for 1-month suicide attempts detection (0.93), followed by lifetime (0.89), and 1-year detection (0.87). Among all variables, the Emotion Regulation Questionnaire had the highest contribution, and the positive and negative characteristics of the scales similarly contributed to classification performance. Performance on suicide attempts classification was largely maintained when we only used the top five ranked variables for training (AUROC; 1-month, 0.75, 1-year, 0.85, lifetime suicide attempts detection, 0.87). Our findings indicate that information from self-report clinical scales can be useful for the classification of suicide attempts. Based on the reliable performance of the top five predictors alone, this machine learning approach could help clinicians identify high-risk patients in clinical settings.
ChemInform Abstract: Asymmetric Synthesis of Trans‐Fused Octahydro Pyranopyran Subunits Related to Marine Polyether Toxins. (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
The reaction of M(CO)3(Ph2PCH2CH2PPh2) (M = Fe, Ru) with parahydrogen: probing the electronic structure of reaction intermediates and the internal rearrangement mechanism for the dihydride products (2004)

The photochemical reaction of Ru(CO)(3)(dppe) and Fe(CO)(3)(dppe)(dppe = Ph(2)PCH(2)CH(2)PPh(2)) with parahydrogen has been studied by in situ-photochemistry resulting in NMR spectra of Ru(CO)(2)(dppe)(H)(2) that show significant enhancement of the hydride resonances while normal signals are seen in Fe(CO)(2)(dppe)(H)(2). This effect is associated with a singlet electronic state for the key intermediate Ru(CO)(2)(dppe) while Fe(CO)(2)(dppe) is a triplet. DFT calculations reveal electronic ground states consistent with this picture. The fluxionality of Ru(CO)(2)(dppe)(H)(2) and Fe(CO)(2)(dppe)(H)(2) has been examined by NMR spectroscopy and rationalised by theoretical methods which show that two pathways for ligand exchange exist. In the first, the phosphorus and carbonyl centres interchange positions while the two hydride ligands are unaffected. A second pathway involving interchange of all three ligand sets was found at slightly higher energy. The H-H distances in the transition states are consistent with metal-bonded dihydrogen ligands. However, no local minimum (intermediate) was found along the rearrangement pathways.
Rydberg atom-based sensors for radio-frequency electric field metrology, sensing, and communications (2021)

The recent redefinition of the SI bolsters the push towards quantum-based sensors. Rydberg atoms provide a natural link between atomic quantities and electromagnetic fields, where direct absolute measurements can be challenging. We review recent demonstrations of SI-traceable electric field metrology for both high frequency and static fields, communications reception, and angle-of-arrival detection using Rydberg atom spectroscopy.
Reduced Order Methods: Applications to Nuclear Reactor Core Spatial Dynamics (2015)

In this paper, the capabilities of reduced order methods, with application to nuclear reactor core spatial dynamics, are presented. The potential of reduced order methods with respect to the classical Modal Method approach is firstly addressed. In particular, two modelling approaches based on a Modal Method and on the Proper Orthogonal Decomposition technique, for developing a control-oriented model of nuclear reactor spatial kinetics, are compared. Subsequently, the Reduced Basis method for simulating, in a rapid and reliable way, the movement of control rods is addressed, solving parametrized multi-group neutron diffusion equations both in the time-dependent and stationary formulations. For the latter case, a different sampling technique, within the Reduced Basis framework, has been employed, namely, the centroidal Voronoi tessellation, which allows for a hierarchical parameters space exploration, without relying on an a posteriori error estimation. In this way, the Offline computational time might be sensibly reduced. Finally, a preliminary multi-physics reduced order model of a Lead Fast Reactor single-channel is proposed as proof of concept in order to highlight the potential of reduced order methods in a many-query context.
Random Access in Overlapping Cells (2005)

In this paper we consider cellular networks in which the cells may overlap substantially. Such network architectures, which are motivated by the need to increase the utilization of the available bandwidth by reducing the separation among cells that share the same channel, present new unexplored and fundamental problems. We begin by considering two cells whose assigned user populations overlap spatially, and use a common channel. Consequently, transmissions intended for one base station can cause interference at the other. The interaction between such cells is best exemplified if the protocol of access in each cell is pure random access. For Slotted Aloha, we present a simple mathematical analysis that predicts accurately the maximum achievable throughput. We demonstrate that an invariance (or self-stabilization) property exists that allows the maximum throughput to occur when the expected total channel traffic in each cell is equal to one packet per slot, independent of the degree of overlap of the cells. We then consider larger multi-cell networks and observe the same invariance property in our simulations. Consequently, in planar cellular networks there are no end effects, and coupling is limited only to adjacent overlapping cells. Thus it is possible to evaluate random access throughput by considering only the local neighborhood of a cell.
Two-beam CO2 laser system for laser induced fusion experiments (1976)

As the only well developed laser system potentially suitable for a laser fusion power system, it is critical that the feasibility of fusion induced by CO 2 laser pulses be demonstrated. For the next 2 years (until the 10-kJ 8-beam system at LASL becomes operational), the principal tool for carrying out these investigations will be the Dual Beam Laser System (DBLS). Designed primarily as a prototype for the four modules that will comprise the 10-kJ laser system, DBLS has been upgraded to an experimental target facility by the addition of a high-contrast short-pulse oscillator and the necessary target diagnostic and handling equipment. With target experiments scheduled to begin in the spring of 1976, the DBLS is currently undergoing evaluation to establish its short-pulse performance characteristics.
Data from Defining a Chromatin Pattern that Characterizes DNA-Hypermethylated Genes in Colon Cancer Cells (2023)

&lt;div&gt;Abstract&lt;p&gt;Epigenetic gene regulation is a key determinant of heritable gene expression patterns and is critical for normal cellular function. Dysregulation of epigenetic transcriptional control is a fundamental feature of cancer, particularly manifesting as increased promoter DNA methylation with associated aberrant gene silencing, which plays a significant role in tumor progression. We now globally map key chromatin parameters for genes with promoter CpG island DNA hypermethylation in colon cancer cells by combining microarray gene expression analyses with chromatin immunoprecipitation-on-chip technology. We first show that the silent state of such genes universally correlates with a broad distribution of a low but distinct level of the PcG-mediated histone modification, methylation of lysine 27 of histone 3 (H3K27me), and a very low level of the active mark H3K4me2. This chromatin pattern, and particularly H3K4me2 levels, crisply separates DNA-hypermethylated genes from those where histone deacetylation is responsible for transcriptional silencing. Moreover, the chromatin pattern can markedly enhance identification of truly silent and DNA-hypermethylated genes. We additionally find that when DNA-hypermethylated genes are demethylated and reexpressed, they adopt a bivalent chromatin pattern, which is associated with the poised gene expression state of a large group of embryonic stem cell genes and is characterized by an increase in levels of both the H3K27me3 and H3K4me2 marks. Our data have great relevance for the increasing interest in reexpression of DNA-hypermethylated genes for the treatment of cancer. [Cancer Res 2008;68(14):5753–9]&lt;/p&gt;&lt;/div&gt;
Leukocyte Cell-Derived Chemotaxin 2 Retards Non-Small Cell Lung Cancer Progression Through Antagonizing MET and EGFR Activities (2018)

EGFR-MET signaling is critical for aggressive behaviors of NSCLC and is recognized as a therapeutic target for NSCLC especially for patients with acquired resistance to EGFR-TKI therapy. Our findings demonstrate, for the first time, that LECT2 functions as a suppressor of the progression of NSCLC by targeting EGFR-MET signaling.
Curing and constitutive relationships for polyester mortar (1989)

Abstract The compressive and tensile properties of polyester mortar were studied under various curing conditions, temperature, and strain rate. The curing temperature was varied from room temperature to 80°C. The behavior of polyester mortar was studied using a uniform sand with strain rate and temperature varied between 0.01 to 6 percent strain per minute and 22°C and 120°C, respectively. The strength, failure strain, modulus and stress‐strain relationships of polyester mortar are influenced by the curing method, testing temperature, and strain rate to varying degrees. The influence of test variables on the mechanical properties of polyester mortar are quantified. Pretreating the aggregates with a silane coupling agent further enhances the compressive and tensile strength of the mortar. The compressive modulus and splitting tensile strength of polyester mortar are related to the compressive strength. A constitutive model is used to predict the compressive stress‐strain behavior of polyester mortar.
A metamodel for the Unified Modeling Language: critical analysis and solution (2002)

Nowadays models, rather than code, become the key artifacts of software development. Consequently, this raises the level of requirements for modeling languages on which modeling practitioners should rely in their work. A minor inconsistency of a modeling language metamodel may cause major problems in the language applications; thus with the model driven systems development the solidness of modeling languages metamodels becomes particularly important. At its current state the UML metamodel suggests a significant area for improvement. In this work we present an alternative metamodel that was inspired by RM-ODP standard and that solves the problems of UML. RM-ODP was mentioned in UML specifications as a framework that has already influenced UML. Our metamodel was formalized, thus its resulting models can be simulated and checked for consistency. So, our proposed solution carrying a constructive potential towards improvement of the UML metamodel, may have a real practical impact on the UML specifications.
Structural studies of BaCe0.7Zr0.1Y0.1Pr0.1O3-δ perovskite for IT-SOFCS (2018)

The BaCe0.7Zr0.1Y0.1Pr0.1O3-δ, a perovskite oxide type specimen has been synthesized for application in electrolyte for anode-supported protonic solid oxide fuel cell by the conventional solid state reaction in air at 1350°C for 8 hours. The X-ray diffraction (XRD) experiment and Scanning Electron Microscopy (SEM) were done for structural analysis and Thermogravimetric Analysis (TGA-DTA) has been performed for thermal and differential thermal characterization. Rietveld refinement of the XRD data has been performed by using FullProf software and single phase orthorhombic crystal structure with the Pbnm space group was confirmed. The TG/DTA scan was recorded under constant flow of Argon gas to understand the temperature dependent behaviour of the precursor which exhibits weight loss at 780°C. The SEM image of the pellet surface of the sample shows that the sample sintered at 1350°C was dense without any pore or crack. The structural properties of the sample showed that can be a good candidate as an electrolyte in solid oxide fuel cells (SOFCs).
Products of alkaline peroxide attack on wheat straw, oak, and kenaf (1985)

Wheat straw, oak, and kenaf were partially delignified by treatment with hydrogen peroxide at pH 11.0, and the water-soluble degradation products were characterized. Forty to sixty percent of the solubilized products were larger than 1000 molecular weight (MW), as determined by membrane ultrafiltration. Lignin degradation products in the low-molecular-weight fraction (<1000) consisted primarily of aromatic and aliphatic carboxylic acids.
UNAP: User-Centric Network-Aware Push for Mobile Content Delivery (2009)

The consumer interest in mobile multimedia content is on the rise, driven by the higher bandwidth of 3G networks and by the availability of low-cost high-resolution mobile devices. However, providing a good user experience remains a challenge due to bandwidth bottlenecks at peak time, channel quality variations and high battery drain incurred by long data transmission times at lower bandwidths. Consequently high jitter, buffering delays and frequent network outages are ever so common for mobile multimedia services. The emerging mobile broadcast networks (e.g. BCMCS, MediaFLO, DVB-H) are well suited for efficient delivery of highly popular content but lack the on-demand, interactive and retransmission (for reliability) capabilities by virtue of being one-way. In addition, due to business reasons (e.g. MediaFLO) or technical reasons (e.g. BCMCS) service providers prefer to deliver only a limited number of popular channels over these networks. In this paper we propose a mobile content delivery architecture that takes wireless specifics into account to enhance the user experience with multimedia services. Our solution makes efficient use of the available bandwidth, does network and channel quality- aware content delivery on the unicast 3G network while at the same time efficiently and reliably schedules content delivery over the mobile broadcast network. In our solution the delivered content is pre-cached on the storage available on the mobile device. This provides a better user experience, reduces the peak load on the network, and reduces the battery drain on the mobile device. Motivated by the proposed architecture we study the problem of scheduling content over a hybrid unicast and broadcast mobile network and design efficient algorithms and heuristics for the problem.
Quasi-static versus dynamic failure instabilities in fluid-saturated porous media (2002)

Using a linear perturbation approach, we show that under quasi-static conditions, unbounded growth of perturbations coincides with localization under drained or undrained conditions. Under dynamic loadings, unbounded growth is related either to the emergence of stationary discontinuities (and these are set by drained conditions) or to the appearance of the flutter phenomenon (acceleration waves). For associative behaviour the inception of unbounded growth is always set (under both static and dynamic conditions) by the singularity of the drained acoustic tensor. It is only for non-associative flow that unbounded growth may correspond to undrained localization in quasi-static conditions and to flutter under dynamic conditions.
Modeling of nonidealities in receiver front-end for a simulation of multistatic SAR system (2007)

Novel concepts for Synthetic Radar (SAR) systems are designed to use the potential of multiple transmit or/and receive front-ends. The DBF SAR, HRWS SAR or MIMO SAR improve the quality of the radar image using multiple receiver signals and adequate signal processing algorithms. The processing algorithms are developed with assumption of an ideal transmit and receive system. The effects that could occur in the transmitter or receiver front-end disturb the received signal and resulting Radar image. This paper is a contribution to the investigation of the influence of nonidealities of the SAR receiver. Presented are VKA-representation models of HRWS SAR receiver Developed simulation considers also effects resulting from quantization and digital beamforming processing (DBF). The VKA-representation enables description of the receiver in a compact and simple way.
Enantioselective Rhodium‐Catalyzed Atom‐Economical Macrolactonization (2016)

Abstract A highly attractive route toward macrolactones, which form the cyclic scaffold of a multitude of diverse natural compounds, is described. Although many chemical approaches to this structural motif have been explored, an asymmetric variant of the cyclization is unprecedented. Herein we present an enantioselective macrolactonization through an intramolecular atom‐economical rhodium‐catalyzed coupling of ω‐allenyl‐substituted carboxylic acids. The use of a modified diop ligand, chiral DTBM‐diop, led to high enantioselectivity (up to 93 % ee ). The reaction tolerated a large variety of functionalities, including α,β‐unsaturated carboxylic acids and depsipeptides, and provided the desired macrocycles with very high enantio‐ and diastereoselectivity.
Needle in a Haystack: Mitigating Content Poisoning in Named-Data Networking (2014)

Named-Data Networking (NDN) is a candidate next-generation Internet architecture designed to address some limitations of the current IP-based Internet. NDN uses the pull model for content distribution, whereby content is first explicitly requested before being delivered. Efficiency is obtained via router- based aggregation of closely spaced requests for popular content and content caching in routers. Although it reduces latency and increases bandwidth utilization, router caching makes the network susceptible to new cache-centric attacks, such as content poisoning. In this paper, we propose a ranking algorithm for cached content that allows routers to distinguish good and (likely) bad content. This ranking is based on statistics collected from consumers' actions following delivery of content objects. Experimental results support our assertion that the proposed ranking algorithm can effectively mitigate content poisoning attacks.