gebhart/patrepeval huggingface dataset:
Progress report of the 3rd generation ECR ion sources fabrication (1999)

Recent progress in the construction of the 3rd Generation ECR ion source at the 88-Inch Cyclotron in Berkeley is reported. Test results of a full scale prototype superconducting magnet structure, which was described in the last ECR Ion Source Workshop, lead to an improved coil design for the 3rd Generation ECR ion source. Solenoids of the new design have been fabricated and exceeded the design field values without quench. The new sextupole coils are currently being wound and will be tested this summer. This magnet structure consists of three solenoids and six race track coils with iron poles forming the sextupole. It is described in the report along with the structural support and coil winding specifications. The coils are designed to generate a 4T axial mirror field at injection and 3T at extraction and a radial sextupole field of 2.4 T at the plasma chamber wall. The high axial magnetic field of the 3rd Generation ECR ion source influences ion beam extraction considerably and we have initiated simulations of the extraction and beam transport system in order to enhance transmission through the injection beam line of the cyclotron.
Significance of timing of therapeutic line on effectiveness of nivolumab for metastatic renal cell carcinoma (2022)

The therapeutic efficacy of nivolumab as second-line therapy is expected to be better than that of later therapy.
<title>A Frequency Domain Description Of Interferogram Analysis</title> (1983)

Interferogram analysis is discussed as a sampling problem using the concepts of Fourier analysis. The relative merits of random, raster, and uniform sampling of a wavefront are examined. A relationship between a global least squares fit and interpolation in the spatial domain and transfer functions in the frequency domain is described.
Treatment of Humic Waters By Ozone (1985)

Two different generators for ozone were tested, a traditional electrical discharge generator and a generator based upon UV–irradiation of air at 150–180 nm. It was demonstrated that the traditional generator gave slightly higher reductions in levels of color for equivalent ozone dosages. Both gases affected the molecular weight distribution in the way that the bigger molecules were broken down to smaller ones. No significant difference between the molecular weight reduction efficiency of the gases was found.
Supervised Peer-to-Peer Systems (2006)

In this paper we present a general methodology for designing supervised peer-to-peer systems. A supervised peer-to-peer system is a system in which the overlay network is formed by a supervisor but in which all other activities can be performed on a peer-to-peer basis without involving the supervisor. It can therefore be seen as being between server-based systems and pure peer-to-peer systems. The supervisor only has to store a constant amount of information about the system at any time and only needs to send a small constant number of messages to integrate or remove a peer in a constant amount of time. Thus, with a minimum amount of involvement from the supervisor, peer-to-peer systems can be maintained, for example, that can handle large distributed computing tasks as well as tasks such as file sharing and Web crawling. Furthermore, our concept extends easily to multiple supervisors so that peers can join and leave the network massively in parallel. We also show how to extend the basic system to provide robustness guarantees under the presence of random faults and also adaptive adversarial join/leave attacks. Hence, with our approach, supervised peer-to-peer systems can share the benefits of server-based and pure peer-to-peer systems without inheriting their disadvantages.
Achieving Sub-second Pairwise Query over Evolving Graphs (2023)

Many real-time OLAP systems have been proposed to query evolving data with sub-second latency. Although this feature is highly attractive, it is very hard to be achieved on analytic graph queries that can only be answered after accessing every connected vertex. Fortunately, researchers recently observed that answering pairwise queries is enough for many real-world scenarios. These pairwise queries avoid the exhaustive nature and hence may only need to access a small portion of the graph. Obviously, the crux of achieving low latency is to what extent the system can eliminate unnecessary computations. This pruning process, according to our investigation, is usually achieved by estimating certain upper bounds of the query result in existing systems.
Idiopathic ventricular fibrillation associated with long‐coupled Purkinje ectopy (2023)

Long-coupled fascicular PVCs, traditionally recognized as benign, can be associated with IVF in a subset of patients. They can induce IVF by themselves or in association with short-coupled PVCs.
ChemInform Abstract: CARBODIIMIDIUM‐VERBINDUNGEN ALS REAGENTIEN IN DER ORGANISCHEN CHEMIE (1972)

Abstract Durch mehrstündiges Erhitzen des Diimids (I) mit Methyljodid (II) wird das Carbodiimidiumsalz (III) erhalten, das zur Jodierung von Alkoholen verwendet werden kann: Aus den Alkoholen (IV) bzw. (VI) werden die" Jodide (Va)(39%), (Vb) (18%) (Vc) (81%) bzw. (VII) erhalten.
Detection of web based command & control channels (2011)

Ependymomas are the most common glial tumors of the spinal cord, including the conus medullaris, filum terminale, and cauda equina. This study involved eight ependymomas of the spinal cord encountered during a 29-year period (1968-1996). The male:female ratio was 1:1.7, and the mean age at diagnosis was 33.7 years (range, 13-55 years). The outcome was studied in relation to initial presentation, initial therapy, location of tumor, histology of tumor, and gender after a follow-up period ranging from 2-16 years (mean, 113 months). Complete removal was achieved in six patients. Two patients received postoperative irradiation after partial removal. Histological examination revealed a benign ependymoma in all patients. Patients undergoing gross total excision at initial operation had excellent or good outcomes. We conclude that ependymomas of the spinal cord should be removed completely, if possible. Spine surgeons should be aware of the disease, and magnetic resonance imaging should be used in its detection.
The MTCR Scheme for the Integrated Multiple Rate Mobile Data Networks (2005)

A multiple threshold channel resewation (MTCR) scheme that partitions the system channels into several regions according to call priority for multiple data rate services of the integrated WLAN and GPRS network is proposed. The effect of the overlaid WLAN area size on the traffic performance is investigated. The simulation results demonstrate that compared with the complete sharing (CS) scheme, the proposed MTCR scheme can provide the same new call blocking probability for the different data rate services and lower handoff failure probability in the integrated GPRS/WLAN networks.
High sensitivity gas sensing using hollow core photonic bandgap fibres designed for operation at mid-IR wavelengths (2014)

High sensitivity gas detection is of great interest in the fields of security, medical diagnostics, and environmental and industrial monitoring. Optical absorption methods are well established and the use of fibre based devices has advantages in terms of small footprint, relatively low cost, immunity to electromagnetic interference and potential for distributed sensing; however, they generally suffer from poor sensitivity due to the difficulty of achieving an efficient spatial overlap with gas analytes. The use of Hollow Core Photonic Bandgap Fibres (HC-PBGFs), i.e. a special type of optical fibres that guide light in a hollow core through bandgap effects, enables an extremely efficient sensing platform due to close to 100% overlap between the light and gas in the hollow core and the possibility for long interaction lengths. Furthermore, HC-PBGFs can be designed to operate at mid-IR wavelengths, where conventional fibres cannot operate. We recently demonstrated HC-PBGFs with loss as low as 0.05dB/m at 3.3µm and more than 100nm 3dB transmission bandwidth [1]. The capability of accessing the mid-IR wavelengths is critical for gas sensing, as the fundamental vibrational transitions of many gas molecules (for instance those containing C-H, O-H, N-H groups) fall in this spectral region. By detecting the fundamental absorption bands as opposed to their much weaker overtones in the near IR often targeted by fibre based sensor systems, substantially higher sensitivity can be achieved [2]. Additionally, mid-IR HC-PBGFs have relative large core diameters (~50 µm), which is beneficial in allowing a comparatively faster gas filling and evacuation.
Symbiosis of Carpenter Bees with Uncharacterized Lactic Acid Bacteria Showing NAD Auxotrophy (2023)

Eusocial bees (such as honey bees and bumble bees) harbor core gut microbiomes that are transmitted through social interaction between nestmates. Carpenter bees are not eusocial; however, recent microbiome analyses found that <i>Xylocopa</i> species harbor distinctive core gut microbiomes. In this study, we analyzed the gut microbiomes of three <i>Xylocopa</i> species in Japan between 2016 and 2021 by V1 to V2 region-based 16S rDNA amplicon sequencing, and 14 candidate novel species were detected based on the full-length 16S rRNA gene sequences. All <i>Xylocopa</i> species harbor core gut microbiomes consisting of primarily lactic acid bacteria (LAB) that were phylogenetically distant from known species. Although they were difficult to cultivate, two LAB species from two different <i>Xylocopa</i> species were isolated by supplementing bacterial culture supernatants. Both genomes exhibited an average LAB genome size with a large set of genes for carbohydrate utilization but lacked genes to synthesize an essential coenzyme NAD, which is unique among known insect symbionts. Our findings of phylogenetically distinct core LAB of NAD auxotrophy reflected the evolution of <i>Xylocopa</i>-restricted bacteria retention and maintenance through vertical transmission of microbes during solitary life. We propose five candidate novel species belonging to the families Lactobacillaceae and Bifidobacteriaceae, including a novel genus, and their potential functions in carbohydrate utilization. <b>IMPORTANCE</b> Recent investigations found unique microbiomes in carpenter bees, but the description of individual microbes, including isolation and genomics, remains largely unknown. Here, we found that the Japanese <i>Xylocopa</i> species also harbor core gut microbiomes. Although most of them were difficult to isolate a pure colony, we successfully isolated several strains. We performed whole-genome sequencing of the isolated candidate novel species and found that the two Lactobacillaceae strains belonging to the <i>Xylocopa</i>-specific novel LAB clade lack the genes for synthesizing NAD, a coenzyme central to metabolism in all living organisms. Here, we propose a novel genus for the two LAB species based on very low 16S rRNA gene sequence similarities and genotypic characters.
Regio‐ and Enantioselective Pd‐Catalyzed Allylic Alkylation of Ketones Through Allyl Enol Carbonates. (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
A Usability Comparison of Laser Suction Handpieces for Percutaneous Nephrolithotomy (2016)

Suction laser handpieces offer an option to treat renal stones via PCNL, with limited differences noted in most surgeon ratings between devices.
Nanoimprint system development and status for high-volume semiconductor manufacturing (2015)

Imprint lithography has been shown to be an effective technique for replication of nano-scale features. Jet and Flash Imprint Lithography* (J-FIL*) involves the field-by-field deposition and exposure of a low viscosity resist deposited by jetting technology onto the substrate. The patterned mask is lowered into the fluid which then quickly flows into the relief patterns in the mask by capillary action. Following this filling step, the resist is crosslinked under UV radiation, and then the mask is removed, leaving a patterned resist on the substrate. The purpose of this paper is to describe the technology advancements made to both wafer imprint and mask replication systems that will be applied for the fabrication of advanced devices such as NAND Flash memory and DRAM. Overlay of better than 5nm (mean + 3sigma) has been demonstrated, and throughputs of better than 10 wafers per imprint station are now routinely achieved. Defectivity has been reduced by more than two orders of magnitude and particle adders within the tool have come down by approximately four orders of magnitude. A pilot line tool, the FPA- 1100 NZ2, was used to generate most of the results in this work. Additionally, particle control in a mask replication tool is addressed, with the purpose of extending the
The Watermark Copy Attack (2000)

Research in digital watermarking has progressed along two paths. While new watermarking technologies are being developed, some researchers are also investigating di erent ways of attacking digital watermarks. Common attacks to watermarks usually aim to destroy theembedded watermark or to impair its detection. In this paper we propose a conceptually new attack for digitally watermarked images. The proposed attack doesnot destroy anembedded watermark, but copies it from one image to a di erent image. Although this new attack does not destroy awatermark or impair its detection, it creates new challenges, especially when watermarks are used for copyright protection and identi cation. The process of copying the watermark requires neither algorithmic knowledge of the watermarking technology nor the watermarking key. The attack is based on an estimation of the embedded watermark in the spatial domain through a ltering process. The estimate of the watermark is then adapted and inserted into the target image. To illustrate the performance of the proposed attack we applied it to commercial and non-commercial watermarking schemes. The experiments showed that the attack is very e ective in copying a watermark from one image to a di erent image. In addition, we have a closer look at application dependent implications of this new attack.
Stabdump—a dump interpreter program to assist debugging (1980)

Abstract Program development can be greatly speeded by a dump analysis program which makes the state of a program more visible to the programmer. A single comprehensive analysis presenting as much of the relevant material in as concise a manner as possible has proved superior in use to the alternative of interactive analysis one item‐at‐a‐time. The methods adopted in the STAB utility to achieve comprehensive and concise output are described. The system and compiler modifications necessary to support this type of system are discussed.
Azimuthally Anisotropic 3D Velocity Continuation (2011)

We extend time-domain velocity continuation to the zero-offset 3D azimuthally anisotropic case. Velocity continuation describes how a seismic image changes given a change in migration velocity. This description turns out to be of a wave propagation process, in which images change along a velocity axis. In the anisotropic case, the velocity model is multiparameter. Therefore, anisotropic image propagation is multidimensional. We use a three-parameter slowness model, which is related to azimuthal variations in velocity, as well as their principal directions. This information is useful for fracture and reservoir characterization from seismic data. We provide synthetic diffraction imaging examples to illustrate the concept and potential applications of azimuthal velocity continuation and to analyze the impulse response of the 3D velocity continuation operator.
Supplementary Table 1 from Human CTL Epitopes Prostatic Acid Phosphatase-3 and Six-Transmembrane Epithelial Antigen of Prostate-3 as Candidates for Prostate Cancer Immunotherapy (2023)

Supplementary Table 1 from Human CTL Epitopes Prostatic Acid Phosphatase-3 and Six-Transmembrane Epithelial Antigen of Prostate-3 as Candidates for Prostate Cancer Immunotherapy
Experimental validation of TOA-based methods for microphones array positions calibration (2016)

This study is an experimental validation of a new closed-form method for automatic array position calibration, based on time of arrival (TOA) measurements between sources and sensors. An experiment with a large array composed of 121 microphones and a dozen of sources has been set up. We first show that, when considering the whole array, this calibration method gives results on par with a reference state-of-the-art acoustic method. We then show experimentally that the new method provides significantly better results when the number of sources and microphones decreases, confirming numerical simulations. We conclude the paper with a discussion on methodological issues for array position calibration.
Engineering of Electromechanical Oxides by Symmetry Breaking (2023)

Abstract Complex oxides exhibit a wide range of fascinating functionalities, such as ferroelectricity, piezoelectricity, and pyroelectricity, which are indispensable for cutting‐edge electronics, energy, and information technologies. The intriguing physical properties of these complex oxides arise from the complex interplay between lattice, orbital, charge, and spin degrees of freedom. Here, it is reviewed how electromechanical properties can be achieved/improved by artificially breaking the symmetry of centrosymmetric oxides via engineering thermodynamic variables such as stress, strain, electric field, and chemical potentials. The mechanisms that have been utilized to break the inherent symmetry of conventional materials that lead to novel functionalities and applications are explored. It is highlighted that access to “hidden phases,” which otherwise are prohibited, could uncover opportunities to host exotic properties, such as piezoelectricity, pyroelectricity, etc. This review not only reports how to engineer intrinsically nonpolar and centrosymmetric oxides for emergent properties, but also has implications for manipulating polar functional materials for better performance.
Effect of fiber-rich powder prepared from mangifera pajang peels on cardiovascular factors in hypercholesterolemic model. (2011)

The potential hypolipidemic effect of a fiber rich powd,er (FRP) containing antioxidant polyphenols in a hypercholesterolemia model was investigated. Lipid profile, total antioxidant status, and malondialdehyde were measured. The antioxidant enzymes (glutathione peroxidase and superoxide dismutase) were also determined. The consumption of FRP in hypercholesterolemic condition, improved the blood lipid profile and total antiox·dant status (TAS). FRP exhibited an important hypolipidemic action, returning t acylgly 01 levels in hypercholesterolemic animals to normal values. The hypocholeste IC effect was also observed, reducing total and low-density lipoprotein cholesterol. FRP with a hypercholesterolemic diet improved the lipidemic profile and reduced lipid peroxidation, suggesting that FRP might defend against cellular damage and contribute to a reduction of cardiovascular risk and thus would put forward the potential·application of this FRP as a functional food ingredient and used in the preparation of a low calorie and high fibre diet.
Mitogen-activated Protein Kinases Mediate Activator Protein-1-dependent Human Inducible Nitric-oxide Synthase Promoter Activation (2001)

Inducible nitric-oxide synthase (iNOS) is an important signaling protein involved in the regulation of biological processes (e.g. vasodilation, inflammation) and is subject to transcriptional regulation by cytokines and lipopolysaccharide (LPS). Full activation of the human iNOS (hiNOS) promoter by cytokines (i.e., tumor necrosis factor-alpha, interleukin-1beta, interferon-gamma (IFN-gamma)) required downstream and upstream nuclear factor-kappaB (-115, -8283) and activator protein-1 (AP-1) (-5115, -5301) transcription factor binding sites. Human lung epithelial (A549) cells were transiently transfected with luciferase reporter plasmids containing an 8.3-kilobase human iNOS promoter to examine the molecular signaling events necessary for hiNOS transcriptional activation. The combination of LPS and IFN-gamma, but neither alone, increased hiNOS promoter activity 28-fold, in a reaction requiring two critical AP-1 (JunD-Fra-2) promoter binding sites. Mitogen-activated protein kinases (MAPKs) were assessed as potential activators of AP-1 and the hiNOS promoter. Both pharmacological and molecular inhibitors of the extracellular signal-related kinase (ERK) and p38 pathways reduced cytokine mixture (CM)- and LPS/IFN-gamma-induced promoter activation. By gel retardation analysis, the addition of MAP/ERK kinase-1 and p38 inhibitors significantly diminished AP-1 binding in both CM- and LPS/IFN-gamma-stimulated cells. Thus, p38- and ERK-dependent pathways, through effects on the AP-1 complex, activate the hiNOS promoter in cells stimulated with CM or LPS/IFN-gamma.
Socratic Learning: Correcting Misspecified Generative Models using Discriminative Models (2016)

A challenge in training discriminative models like neural networks is obtaining enough labeled training data. Recent approaches use generative models to combine weak supervision sources, like user-defined heuristics or knowledge bases, to label training data. Prior work has explored learning accuracies for these sources even without ground truth labels, but they assume that a single accuracy parameter is sufficient to model the behavior of these sources over the entire training set. In particular, they fail to model latent subsets in the training data in which the supervision sources perform differently than on average. We present Socratic learning, a paradigm that uses feedback from a corresponding discriminative model to automatically identify these subsets and augments the structure of the generative model accordingly. Experimentally, we show that without any ground truth labels, the augmented generative model reduces error by up to 56.06% for a relation extraction task compared to a state-of-the-art weak supervision technique that utilizes generative models.
Dépôt de films minces de silicium et de nitrures de silicium par pulvérisation cathodique réactive magnétron (2006)

Doctorat en Sciences
Novel method to measure bulk absorption in optically transparent materials (2000)

A novel method to measure low absorption of pulsed laser radiation by materials with high optical transparency is demonstrated. The absorbed energy generates a temperature gradient and thus a refractive index profile. A probe laser beam is deflected by the refractive index profile and its deflection is a measure of pure volume absorption without interference from surface effects. Numerical calculations were carried out to estimate the sensitivity of the discussed laser induced deflection (LID) arrangement and to optimize the path of the probe beam in relation to the irradiated field within the sample. The experimental results agree sufficiently with numerical calculations by finite element method combined with raytracing procedures. Because the transparency is not measured directly a calibration is necessary. To provide this, a sample with known bulk absorption coefficient and thermal properties was used. In order to compensate probe beam fluctuations in air outside the sample, a double beam arrangement was designed. The LID method is applied to investigate fused silica with high ultraviolet (UV) transparency under KrF excimer laser irradiation (λ=248 nm). A He/Ne laser serves as probe beam source. Using sample dimensions of 20×20×10 mm3 and UV beam cross sections of 5×5 mm2 absorbed power down to 1 mW is detected. At typical irradiation conditions (50 s−1, 300 mJ/cm2), this value corresponds with an absorption coefficient of around 2.5×10−4 cm−1. The limitation of the absorption measurement depends on the input power of the pump laser.