gebhart/patrepeval huggingface dataset:
Peroxid‐induzierte thioladdition an polybutadien (1995)

Abstract Die radikalische Addition von 1‐Octanthiol oder 3‐(Trimethoxysily)‐1‐propanthiol an die 1,2‐ bzw. 1,4‐cis‐Doppelbindungen des Polybutadiens erfolgt redox‐induziert mit Dibenzoylperoxid (DBPO) bei Raumtemperatur ohne nachweisbare Nebenreaktionen. Trans‐konfigurierte Doppelbindungen reagieren unter gleichen Bedingungen nicht. Die Molmassenverteilung der Additionsprodukte ist ähnlich eng wie die des reinen Polybutadiens.
Table S2 from Improved Risk-Adjusted Survival for Melanoma Brain Metastases in the Era of Checkpoint Blockade Immunotherapies: Results from a National Cohort (2023)

&lt;p&gt;table s2&lt;/p&gt;
Removal of subsurface fluorescence in cryo-imaging using deconvolution (2010)

We compared image restoration methods [Richardson-Lucy (RL), Wiener, and Next-image] with measured "scatter" point-spread-functions, for removing subsurface fluorescence from section-and-image cryo-image volumes. All methods removed haze, delineated single cells from clusters, and improved visualization, but RL best represented structures. Contrast-to-noise and contrast-to-background improvement from RL and Wiener were comparable and 35% better than Next-image. Concerning detection of labeled cells, ROC analyses showed RL ≈Wiener > Next-image >> no processing. Next-image was faster than other methods and less prone to image processing artifacts. RL is recommended for the best restoration of the shape and size of fluorescent structures.
ChemInform Abstract: The Effect of 5‐Substitution on the Electrochemical Behavior and Antitubercular Activity of PA‐824. (2011)

Abstract Substitution at the imidazole ring of title compound (I) greatly influences reduction and stability of the corresponding nitro radical anion.
Distinctive physical effects and applications approaching the relativistic lambda-cubed regime (2006)

Using small amounts of optical energy, it is possible to drive matter with relativistic intensity. We show unique energy transport properties, X-ray production, and efficient attosecond phenomena coming from microscopic plasmas driven by precisely focused ultrashort pulses of light.
Indentation and Fracture of Hybrid Sol-Gel Silica Films (2012)

Organic-inorganic hybrid thin films fabricated using sol-gel processing have many compelling properties that render them quite attractive for many applications, including optics, electronics, sensors and corrosion and scratch resistant films (Haas & Wolter, 1999; Sanchez et al., 2005). Organic-inorganic hybrid network materials have received much interest as transparent functional coatings on polymer substrates (Haas & Wolter, 1999; Haas et al., 1999a) and barrier coatings on metals (Metroke et al., 2001). Compared to glass, polymers such as polycarbonate (PC) and glycol bis(allyl carbonate) (CR-39) exhibit several advantageous physical and mechanical properties, such as high impact resistance and reduced weight, but also have the significant disadvantage of higher refractive index resulting in greater surface reflections as well as a much lower tolerance to abrasion. These drawbacks have limited their exploitation as a replacement to glass, especially for ophthalmic lenses where reflections and scratches on lenses can significantly obscure vision. The incorporation of a film or coating on glass or polymer can have immense benefits as is the case in the eyewear industry where several layers are deposited on polymer substrates to overcome substrate limitations (Samson, 1996; Schottner, 2001). By controlling the chemistry of the organic component incorporated in hybrid films, the physical and mechanical properties can be readily adjusted to realise specific attributes such as scratch resistance. Yet a vital reliability issue for film-on-substrate systems is the intrinsic mechanical properties of the film and adhesion to the substrate (Ignat et al., 1999).
Introduction (2003)

Abstract This chapter discusses the contents of this volume, which is about management of currency crises in emerging markets. The collection of papers in this volume were presented at a National Bureau of Economic Research Conference, held in Monterey, California in March 2001. This volume is divided into three parts which can be seen as three phases counting forward from the moment that a country is hit by a crisis. The first part describes the immediate defense of the currency regime under attack, the second examines the adjustment programs that follow crises and the third evaluates the effectiveness of the adjustment programs.
Cystic Hygroma: A Preliminary Genetic Study and a Short Review from the Literature (2018)

A review of the literature to date revealed that an association exists between CH and hereditary lymphedema and, similar to lymphedema, CH can be inherited in autosomal recessive and autosomal dominant manner, with the latter most likely associated with a better prognosis. About KDR and KRIT1 genes, no other similar associations are reported in the literature and caution is needed in their interpretation. In conclusion, we thought that a genetic test for the outcome of familial CH could be of enormous prognostic value.
Small molecule CCR2 antagonists (2007)

Monocyte chemoattractant protein-1 (MCP-1), also known as CCL2, is a member of the CC family of chemokines. During inflammatory conditions, the production of MCP-1 is upregulated in both immune and non-immune cell types including macrophages, mast cells, fibroblasts, endothelial and epithelial cells, smooth muscle cells, and astrocytes. MCP-1 is a potent activator and chemoattractant of leukocytes such as monocytes, macrophages, activated T cells, dendritic cells, and natural killer (NK) cells [1]. The biological effects of MCP-1 are mediated by interaction with its primary receptor, CCR2. In addition to inducing chemotaxis, other cellular responses induced by MCP-1 include integrin activation, inflammatory cytokine production, and histamine release [2, 3].
Uniform light delivery in volumetric optoacoustic tomography (2019)

Accurate image reconstruction in volumetric optoacoustic tomography implies the efficient generation and collection of ultrasound signals around the imaged object. Non-uniform delivery of the excitation light is a common problem in optoacoustic imaging often leading to a diminished field of view, limited dynamic range and penetration, as well as impaired quantification abilities. Presented here is an optimized illumination concept for volumetric tomography that utilizes additive manufacturing via 3D printing in combination with custom-made optical fiber illumination. The custom-designed sample chamber ensures convenient access to the imaged object along with accurate positioning of the sample and a matrix array ultrasound transducer used for collection of the volumetric image data. Ray tracing is employed to optimize the positioning of the individual fibers in the chamber. Homogeneity of the generated light excitation field was confirmed in tissue-mimicking agar spheres. Applicability of the system to image entire mouse organs ex vivo has been showcased. The new approach showed a clear advantage over conventional, single-sided illumination strategies by eliminating the need to correct for illumination variances and resulting in enhancement of the effective field of view, greater penetration depth and significant improvements in the overall image quality.
Autoimmune Hepatitis: A Review of Current Diagnosis and Treatment (2011)

Autoimmune hepatitis (AIH) is a chronic inflammatory disorder characterized by periportal inflammation, elevated immunoglobulins, autoantibodies, and a dramatic response to immunosuppression. An environmental agent is hypothesized to trigger an immune-mediated attack directed against liver antigens in genetically predisposed individuals. A plethora of clinical presentations can be seen ranging from chronic indolent disease to fulminant hepatic failure, and diagnosis requires exclusion of other causes of liver disease. Corticosteroid therapy must be instituted early and modified in an individualized fashion. Treatment decisions are often complicated by the diverse clinical manifestations, uncertainty about natural history, evolving ideas about treatment end points, and a multitude of alternative immunosuppressive agents. Achieving normal liver tests and tissue is the ideal treatment end point, but needs to be weighed against the risk of side effects. Decompensated patients may benefit from early liver transplantation. Long-term prognosis is excellent with early and aggressive initiation of therapy. Our paper discusses AIH, giving a detailed overview of its clinical presentation, risk factors, immunopathogenesis, up-to-date diagnostic criteria, current updates in therapy with a brief discussion of AIH in pregnancy, and long-term implications for cirrhosis and hepatocellular carcinoma in AIH patients.
Cyber Physical Protection for Natural Gas Compression (2022)

The secure transport of natural gas through North American pipelines is vital for both home and industrial purposes. GE in collaboration with Baker Hughes and Idaho National Laboratory, completed a US Department of Energy grant program to develop a new cyber-physical protection system that monitors the large compressor stations used to boost pressure and maintain proper gas flow. Algorithms were developed to detect the presence of a cyber-attack that impacts the compressor station physical processes, locate the critical functions being manipulated, and potentially neutralize the attack allowing continued operations. The technology was successfully demonstrated at an operating compressor facility located in New York state.
Layer-Structured Copper Antimony Chalcogenides (CuSbSexS2–x): Stable Electrode Materials for Supercapacitors (2014)

The ever-growing need for energy generation and storage applications demands development of materials with high performance and long-term stability. A sizable number of chalcogenide-based materials have been investigated for supercapacitor applications. Layer-structured chalcogenides are advantageous in terms of providing large surface area with good ionic conductivity and ability to host a variety of atoms or ions between the layers. CuSbS2 is a ternary layered chalcogenide material that is composed of earth abundant and less-toxic elements. For the first time, we have developed a simple colloidal method for the synthesis of CuSbSexS2–x mesocrystals over the whole composition range (0 ≤ x ≤ 2) by substitution of S with Se. Our approach yields mesocrystals with belt-like morphology for all the compositions. X-ray diffraction results show that substitution of sulfur with selenium in CuSbS2 enables tuning the width of the interlayer gap between the layers. To investigate the suitability of CuSbSexS2–x mesocrystals for supercapacitor applications, we have carried out electrochemical measurements by cyclic voltammetry and galvanostatic charge–discharge measurements in 3 M KOH, NaOH and LiOH electrolytes. Our investigations reveal that the mesocrystals exhibit promising specific capacitance values with excellent cyclic stability. The unique properties of CuSbSexS2–x mesocrystals make them attractive both for solar energy conversion and energy storage applications.
Echocardiographic evaluation of extracardiac masses. (1978)

Echocardiography was performed on 5 patients with extracardiac masses. Four patients had solid tumours and the fifth had a cystic intrapericardial haematoma. Case 1 showed dense echoes anterior to the aortic root and over the right ventricle. Thoracotomy disclosed malignant infiltration ofthe anterior heart wall. The echocardiogram of case 2 showed a dense mass behind the anterior mitral leaflet, left ventricle, and the left atrium. Bronchoscopy disclosed a carcinoma of the left bronchus. An x-ray film of case 3 was suggestive of a pericardial effusion; no echoes were recordable from the left sternal border, and echocardiography from the right sternal border showed no evidence ofpericardial effusion. Necropsy showed a sarcoma which displaced the heart to the right. The ultrasound recording on case 4 in the supine position showed a dilated right ventricle and right ventricular outflow tract, and no evidence of pericardial effusion. In the left lateral position a large space in front of the right ventricle and a paradoxical decrease in right ventricular size were noted. Surgery showed an intrapericardial cystic haematoma anterior to the right ventricle. Echocardiography on case 5 showed a pericardial effusion and thickening (1.5 cm) of the anterior wall of the right ventricle. At operation a lymphoma infiltrating anterior wall of the right ventricle and a pericardial effusion were found.
Inter-laminar flux and eddy current losses in a circumferentially cooled stator core (2010)

The circumferential cooling system, which provides highly effective, integrated but low-cost motor cooling, is introduced. This work is focussed particularly on magnetic effects, which arise from the special construction of the stator core. An explanation for the existence of inter-laminar flux is given and equations for the prediction of its absolute value are derived. Two approaches, an analytical and a numerical one, for the estimation of power losses due to inter-laminar flux are introduced. In agreement with the calculation results, measurements prove that power losses due to axial flux are very small and are not a concern for the design of a circumferentially cooled machine.
Self-Diffusion Coefficient of Carbon Dioxide (1965)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Thomas A. Pakurar, John R. Ferron; Self‐Diffusion Coefficient of Carbon Dioxide. J. Chem. Phys. 15 October 1965; 43 (8): 2917–2918. https://doi.org/10.1063/1.1697240 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioThe Journal of Chemical Physics Search Advanced Search |Citation Search
A Central Role for Foxp3+ Regulatory T Cells in K-Ras-Driven Lung Tumorigenesis (2009)

Foxp3+ regulatory T cells are required for K-Ras-mediated lung tumorigenesis in mice. These studies support clinical testing of rapamycin or other agents that target Treg in K-Ras driven human lung cancer.
Image-based pen-and-ink illustration (1997)

This dissertation addresses the problem of creating pen-and-ink style illustrations on a computer by means of a high-level user interface. We present a system in which the user creates illustrations starting from greyscale images. She specifies the texture and orientation of components within an image by interacting with a painting-style interface. The system then transforms the image into a pen-and-ink drawing by precisely placing and orientating the individual pen strokes that compose the illustration. By encoding the principles developed by pen-and-ink artists over decades, the system aims to support the creation of illustrations capable of much of the flexibility and power of traditional pen and ink.
Development of a Roll-Off Container Handling and Dumping System (Ground Level or into a Railroad Car) for Off-Highway Articulated Trucks (1998)

&lt;div class="htmlview paragraph"&gt;This paper describes the development and manufacture of roll-off container handling systems for off-highway articulated trucks. This presentation reviews systems incorporating four unique products covering various roll-off container handling alternatives. The various components described and, depending on the style of the system, incorporated into a system are:&lt;/div&gt; &lt;div class="htmlview paragraph"&gt; &lt;ol class="list nostyle"&gt; &lt;li class="list-item"&gt; &lt;span class="li-label"&gt;1.&lt;/span&gt; &lt;div class="htmlview paragraph"&gt;An off-highway truck “J”-Hook arrangement for picking roll-off containers up off of the ground and pulling them onto a haulage vehicle.&lt;/div&gt; &lt;/li&gt; &lt;li class="list-item"&gt; &lt;span class="li-label"&gt;2.&lt;/span&gt; &lt;div class="htmlview paragraph"&gt;An automatic tailgate locking and opening system for roll-off containers vs. a manual vehicle driver dependent door/tailgate system.&lt;/div&gt; &lt;/li&gt; &lt;li class="list-item"&gt; &lt;span class="li-label"&gt;3.&lt;/span&gt; &lt;div class="htmlview paragraph"&gt;A scissors lift for lifting roll-off containers to be dumped into various other vessels (railroad gondola cars, etc.).&lt;/div&gt; &lt;/li&gt; &lt;li class="list-item"&gt; &lt;span class="li-label"&gt;4.&lt;/span&gt; &lt;div class="htmlview paragraph"&gt;A unique “J”-Hook interface for standard 20-ft. intermodal roll-off shipping containers so they can be hooked onto and handled with a “J”-Hook.&lt;/div&gt; &lt;/li&gt; &lt;/ol&gt; &lt;/div&gt; &lt;div class="htmlview paragraph"&gt;Both the automatic locking/unlocking tailgate and the scissors lift are features which may or may not be incorporated in every unit. The equipment discussed in this paper opens new avenues for off-highway trucks in steel mills, landfills, quarries, etc.&lt;/div&gt;
Faculty Opinions recommendation of Functional specialization of beta-arrestin interactions revealed by proteomic analysis. (2007)

Beta-arrestins are cytosolic proteins that form complexes with seven-transmembrane receptors after agonist stimulation and phosphorylation by the G protein-coupled receptor kinases. They play an essential role in receptor desensitization and endocytosis, and they also serve as receptor-regulated signaling scaffolds and adaptors. Moreover, in the past decade, a growing list of protein-protein interactions of beta-arrestins pertinent to these functions has been documented. The discovery of several novel functions of beta-arrestins stimulated us to perform a global proteomics analysis of beta-arrestin-interacting proteins (interactome) as modulated by a model seven-transmembrane receptor, the angiotensin II type 1a receptor, in an attempt to assess the full range of functions of these versatile molecules. As determined by LC tandem MS, 71 proteins interacted with beta-arrestin 1, 164 interacted with beta-arrestin 2, and 102 interacted with both beta-arrestins. Some proteins bound only after agonist stimulation, whereas others dissociated. Bioinformatics analysis of the data indicates that proteins involved in cellular signaling, organization, and nucleic acid binding are the most highly represented in the beta-arrestin interactome. Surprisingly, both S-arrestin (visual arrestin) and X-arrestin (cone arrestin) were also found in heteromeric complex with beta-arrestins. The beta-arrestin interactors distribute not only in the cytoplasm, but also in the nucleus as well as other subcellular compartments. The binding of 16 randomly selected newly identified beta-arrestin partners was validated by coimmunoprecipitation assays in HEK293 cells. This study provides a comprehensive analysis of proteins that bind beta-arrestin isoforms and underscores their potentially broad regulatory roles in mammalian cellular physiology. PMID: 17620599 Funding information This work was supported by: NHLBI NIH HHS, United States Grant ID: R01 HL070631 NCRR NIH HHS, United States Grant ID: P41 RR11823 NHLBI NIH HHS, United States Grant ID: R01 HL016037 NCRR NIH HHS, United States Grant ID: P41 RR011823 NHLBI NIH HHS, United States Grant ID: HL16037 NIMH NIH HHS, United States Grant ID: 5R01MH067880-02 NIMH NIH HHS, United States Grant ID: R01 MH067880 More Less keyboard_arrow_down
New Generation Low Power Radiation Survey Instruments (1984)

A number of new, ultra-low-powered radiation instruments have recently been developed at Los Alamos. Among these are two instruments which use a novel power source to eliminate costly batteries. The newly developed gamma detecting radiac, nicknamed the Firefly, and the alpha particle detecting instrument, called the Simple Cordless Alpha Monitor, both use recent advances in miniaturization and power-saving electronics to yield devices which are small, rugged, and very power-frugal. The two instruments consume so little power that the need for batteries to run them is eliminated. They are, instead, powered by a charged capacitor which will operate the instruments for an hour or more. Use of a capacitor as a power source eliminates many problems commonly associated with battery-operated instruments, such as having to open the case to change batteries, battery storage life, availability of batteries in the field, and some savings in weight. Both line power and mechanical sources are used to charge the storage capacitors which power the instruments.
The Related Adhesion Focal Tyrosine Kinase (RAFTK) Is Tyrosine Phosphorylated and Participates in Colony-Stimulating Factor-1/Macrophage Colony-Stimulating Factor Signaling in Monocyte-Macrophages (1998)

RAFTK, a novel nonreceptor protein kinase, has been shown to be involved in focal adhesion signal transduction pathways in neuronal PC12 cells, megakaryocytes, platelets, and T cells. Because focal adhesions may modulate cytoskeletal functions and thereby alter phagocytosis, cell migration, and adhesion in monocyte-macrophages, we investigated the role of RAFTK signaling in these cells. RAFTK was abundantly expressed in THP1 monocytic cells as well as in primary alveolar and peripheral blood-derived macrophages. Colony-stimulating factor-1 (CSF-1)/macrophage colony-stimulating factor (M-CSF) stimulation of THP1 cells increased the tyrosine phosphorylation of RAFTK; similar increases in phosphorylation were also detected after lipopolysaccharide stimulation. RAFTK was phosphorylated with similar kinetics in THP1 cells and peripheral blood-derived macrophages. Immunoprecipitation analysis showed associations between RAFTK and the signaling molecule phosphatidylinositol-3 (PI-3) kinase. PI-3 kinase enzyme activity also coprecipitated with the RAFTK antibody, further confirming this association. The CSF-1/M-CSF receptor c-fms and RAFTK appeared to associate in response to CSF-1/M-CSF treatment of THP1 cells. Inhibition of RAFTK by a dominant-negative kinase mutant reduced CSF-1/M-CSF–induced MAPK activity. These data indicate that RAFTK participates in signal transduction pathways mediated by CSF-1/M-CSF, a cytokine that regulates monocyte-macrophage growth and function.
Effect of transplantation of allogeneic multipotent mesenchymal bone marrow stromal cells on regeneration of liver after extended hepatectomy (experimental study) (2018)

Multipotent mesenchymal stromal cells can be a drug for treatment of acute liver failure. The purpose of this study was to assess the effect of multipotent mesenchymal stromal cells on the proliferative, mitotic activity of hepatocytes and morphometric criteria for the regeneration of liver parenchyma after 68 % partial hepatectomy in rats. The number of mitosis, PCNA positive cells, diameter of nucleus of hepatocytes, size of hepatocytes, nuclear-cytoplasmic ratio (NCR), the area of hepatic lobules were evaluated on 1, 2, 4, 14 days after surgery. The results of the study showed that intravenous administration of allogeneic mesenchymal multipotent stromal cells from bone marrow after extended hepatectomy increase the number of proliferating hepatocytes (PCNA positive cells), but does not affect the number of mitoses, the diameter of the nucleus, the area of hepatocytes, NCR and hepatic lobules. Probably, at this time, regeneration proceeds primarily through an intracellular mechanism.
Wavelength control of a DBR laser diode using a micromachined external mirror (2017)

Single-mode wavelength-stabilized light sources are key devices for spectroscopic applications, optical sensors, wavelength division multiplexing systems. Among the variety of wavelength stabilization schemes, external cavity lasers have been widely used to achieve, with narrow spectral linewidth and wavelength tunability, stable single mode oscillation at a specified wavelength.