gebhart/patrepeval huggingface dataset:
Phosphorus Supplementation Recovers the Blunted Diet-Induced Thermogenesis of Overweight and Obese Adults: A Pilot Study (2016)

Diet-induced thermogenesis (DIT) is believed to be largely related to ATP production, which is dependent on phosphorus (P) availability. We aimed to test the effect of P addition on DIT of lean and overweight/obese healthy subjects. DIT was measured with or without P in 10 lean and 13 overweight/obese adults in a double-blind randomized cross-over pilot study with one week washout period. After 10 h overnight fast, resting metabolic rate, respiratory quotient, and substrate utilization were measured at fasting and every 30 min for 3 h after subjects drank a standardized glucose solution, with P (500 mg) or placebo pills. Subjective ratings of hunger and satiety were assessed before and after the end of each experiment using validated visual analogue scale (VAS) questionnaires. Overweight/obese subjects had a blunted DIT with placebo, while P supplementation induced a 23% increase in their DIT area under the curve (<i>p</i> < 0.05), which was associated with a significant increase in carbohydrate oxidation. Subjects had lower appetite following P supplementation, which was expressed as a significantly (<i>p</i> = 0.02) lower desire to eat a meal (4.0 ± 0.7 cm) compared with placebo (5.8 ± 0.9 cm). P supplementation recovers the blunted diet-induced thermogenesis in overweight and obese subjects and enhances their postprandial satiety.
Effect of ketamine on cerebral cortical blood flow and metabolism in rabbits. (1987)

The effects of intravenous ketamine (1 mg/kg) on cerebral cortical blood flow and O2 uptake were evaluated in 13 anesthetized, ventilated rabbits. Blood flow was measured either directly (Group 1) or by the H2 clearance method (Group 2). In those animals of Groups 1 and 2 with normal control arterial pH (pHa), ketamine produced a significant increase in cerebral cortical blood flow of 18 and 34%, respectively, but had no effect on cerebral cortical O2 uptake. However, in rabbits with low control pHa, ketamine caused an increase in blood flow (30%) accompanied by a significant increase in O2 uptake (22%). Ketamine produced nonsignificant changes in mean arterial blood pressure and arterial blood gases, except for a significant reduction in pressure in animals with low pHa. It is concluded that ketamine is a cerebral vasodilator without cerebral metabolic effect when mean arterial blood pressure and arterial PCO2, PO2, and pH are held constant at physiologic levels. The vasodilator effect of ketamine is probably due to direct dilating action or activation of a cholinergic cerebral vasodilator system.
[Seroepidemiology of cysticercosis in Mexico]. (1992)

The seroprevalence of cysticercosis indicate that there is a high risk of contact with Taenia solium in Mexico, including both genders and all regions, socioeconomic group, and ages. There are some statistically significant differences in risk of contact, affecting principally the center and southeast of the country, rural areas, handicapped persons, children, old people and women. However, these differences are small. This study emphasizes the fact that the risks of infection by Taenia solium are important in all groups, and therefore, the programs for the control of this disease should be focused at the entire population and emphasize strategies for social development.
New Low Chromium Ferritic Pressure Vessel Steels (1988)

Much progress has been made in developing chromium-molybdenum steels with improved hardenability, elevated temperature strength, toughness, and resistance to environment. The new low alloy steels, intended for heavy-wall pressure vessels operating at temperatures in excess of 450°C and pressures up to 30 MPa, are fully bainitic for maximum strength and toughness, and are resistant to temper embrittlement, hydrogen embrittlement, and hydrogen attack. Microstructural studies have shown that alloys containing 3%Cr and 1.5%Mo exhibit improved heat treating characteristics as they rapidly temper to produce stable alloy carbides, which are resistant to hydrogen attack. Such steels could replace 2.25Cr-1Mo steel for service to 480°C. Higher creep strengths can be achieved in modifications of 2.25Cr-1Mo or 3Cr-Mo steels containing up to 0.25% vanadium.
Glial Cell–Derived Cytokines Attenuate the Breakdown of Vascular Integrity in Diabetic Retinopathy (2007)

The blood-retinal barrier (BRB) is a biological unit comprised of specialized capillary endothelial cells firmly connected by intercellular tight junctions and endothelium-surrounding glial cells. The BRB is essential for maintaining the retinal microenvironment and low permeability and is compromised in an early phase during the progression of diabetic retinopathy. Here, we demonstrate that retinoic acid receptor (RAR)alpha stimulants preferentially act on glial cells rather than endothelial cells, resulting in the enhanced expression of glial cell line-derived neurotrophic factor (GDNF) through recruitment of the RARalpha-driven trans-acting coactivator to the 5'-flanking region of the gene promoter. Conversely, RARalpha decreases expression of vascular endothelial growth factor (VEGF)/vascular permeability factor. These gene expression alterations causally limit vascular permeability by modulating the tight junction function of capillary endothelium in a paracrine manner in vitro. The phenotypic transformation of glial cells mediated by RARalpha is sufficient for significant reductions of vascular leakage in the diabetic retina, suggesting that RARalpha antagonizes the loss of tight junction integrity induced by diabetes. These findings reveal that glial cell-derived cytokines such as GDNF and VEGF regulate BRB function, implying that the glial cell can be a possible therapeutic target in diabetic retinopathy.
Multiplex Polymerase Chain Reaction Assay for Simultaneous Detection of Staphylococcus aureus and Streptococcal Causes of Bovine Mastitis (2001)

To improve diagnosis of mastitis in dairy cattle, a multiplex polymerase chain reaction (PCR) assay was developed for the simultaneous detection of the four major bacterial causes of bovine mastitis, Staphylococcus aureus, Streptococcus agalactiae, Streptococcus dysgalactiae, and Streptococcus uberis. The target sequence was the 16S to 23S rRNA spacer regions. The performance of the assay was examined with 117 milk samples collected from a subclinically infected herd, and the diagnostic specificities and sensitivities of the multiplex PCR were compared with conventional culture. PCR was significantly more sensitive than culture for detection of S. aureus and S. uberis, but there were no significant differences in sensitivities between PCR and culture for the detection of S. agalactiae and S. dysgalactiae. The results suggest that this multiplex PCR assay could be used as an alternative method in routine diagnosis for rapid, sensitive, and specific simultaneous detection of S. aureus, S. agalactiae, S. dysgalactiae, and S. uberis in milk samples.
Endoscopic harvest of saphenous vein graft for coronary artery bypass grafting: Saitama–Olympus technique (1998)

The Saitama-Olympus technique to endoscopically harvest the SV is a clinically feasible surgical technique with the unique potential of a significant reduction in morbidity and decreased wound scarring in CABG patients.
Supplementary Data from Neoadjuvant Chemotherapy and Immunotherapy in Luminal B-like Breast Cancer: Results of the Phase II GIADA Trial (2023)

Supplementary Data from Neoadjuvant Chemotherapy and Immunotherapy in Luminal B-like Breast Cancer: Results of the Phase II GIADA Trial
Some optimal partial-unit-memory codes (Corresp.) (1979)

A new class of time-invariant binary convolutional codes is defined, called partial-unit-memory codes. These codes are optimal in the sense of having maximum free distance for given values of <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">R, k</tex> (the number of encoder inputs), and <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">\mu</tex> (the number of encoder memory cells). New optimal codes are given for rates <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">R=l/4, 1/3, 1/2, \and 2/3</tex> with <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">\mu \leq 4 \and k \leq \mu + \3</tex> , whenever such a code is better than previously known An infinite class of optimal partial-unit-memory codes is also constructed based on equidistant block codes.
Crystal Growth, Density Functional Theory, and Scintillation Properties of TlCaX3 (X = Cl, Br, I) (2023)

In this paper we report on the crystal growth, density functional theory calculations, and scintillation properties of TlCaX <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> (X = Cl, Br, I). Crystals were grown by the vertical Bridgman technique in silica ampoules. Crystals of TlCaCl <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> , TlCaBr <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> , and TlCaI <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> belong to the family of the perovskites and have the orthorhombic crystal structure. All three compositions show bright emission under X-ray excitation peaking at 425, 470, and 545 nm, respectively. Light yield increases in the series Cl < Br < I (25,000 – 47,000 ph/MeV).
Masking of the /da/-/ga/ distinction in cochlear impairment (1983)

Discrimination between two 300-ms synthesized syllables, /da/ and /ga/, presented in the middle of a 900-ms narrow-band noise, was measured in three normal and six cochlearly impaired listeners. The segmental distinction was conveyed by the frequency of the initial burst and the form of the third-formant transition, which was 50 ms in duration: For /ga/ the transition started around 1.9 kHz and rose to its steady-state value of 2.5 kHz and for /da/ it started around 3.0 kHz and fell to 2.5 kHz. The narrow-band noises were 300 Hz wide and were centered between 1 and 3.5 kHz. For the normal listeners, the speech was set to 70 dB SPL and the noise to 80 dB SPL. For the impaired listeners, the levels were chosen to yield better than 95% discrimination in the easiest condition, but poor discrimination in the most difficult condition. Both groups of listeners showed the poorest performance when the noise was centered at 2.5 kHz. As the noise moved away from this critical region performance improved for both groups, but more rapidly for the normal listeners. These results indicate that the impaired listeners' reduced frequency selectivity may contribute to their difficulty of discriminating speech in noise. [Supported by NSF and NIH.]
[(CH3)5C5]2Th(CH3)2 surface chemistry and catalysis. Direct NMR spectroscopic observation of surface alkylation and ethylene insertion/polymerization on MgCl2 (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT[(CH3)5C5]2Th(CH3)2 surface chemistry and catalysis. Direct NMR spectroscopic observation of surface alkylation and ethylene insertion/polymerization on MgCl2David. Hedden and Tobin J. MarksCite this: J. Am. Chem. Soc. 1988, 110, 5, 1647–1649Publication Date (Print):March 1, 1988Publication History Published online1 May 2002Published inissue 1 March 1988https://pubs.acs.org/doi/10.1021/ja00213a061https://doi.org/10.1021/ja00213a061research-articleACS PublicationsRequest reuse permissionsArticle Views186Altmetric-Citations49LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
네이버 밴드와 기존 매체 이용의 상호관계에 관한 연구 (Relationships between the Use of Naver Band and Other SNSs) (2016)

Korean Abstract: 사생활 및 개인정보 유출의 우려로 인해 제한된 수의 네트워크만을 집중적으로 관리할 수 있는 이른바 ‘폐쇄형 SNS’의 이용이 증가하고 있다. 이에 따라 본 연구는 이용과 충족이론과 미디어 대체 가설을 바탕으로 대표적인 폐쇄형 SNS인 네이버 밴드의 이용 동기를 밝히고, 이러한 이용 동기가 면대면 커뮤니케이션, 그리고 기타 SNS 및 온라인 커뮤니티 이용과 어떠한 관련이 있는지 실증적으로 분석하였다. 연구결과, 첫째, 네이버 밴드의 이용 동기는 ‘자기확인 및 유행성’, ‘지식 및 정보획득’, ‘오락 및 휴식’, ‘사회적 상호관계’, ‘대인관계유지’ 등 5개의 요인으로 나타났다. 둘째, 네이버 밴드 이용은 카카오그룹 이용과 긍정적인 유의미한 상관관계를 보였으며, 싸이월드와 온라인 커뮤니티 이용과는 부적인 상관관계가 나타났다. 한편 면대면 커뮤니케이션과는 통계적으로 유의미한 상관관계가 나타나지는 않았다. 셋째, 네이버 밴드의 이용 동기와 기타 SNS 및 면대면 커뮤니케이션 이용과의 상관관계를 분석한 결과, 자기확인 및 유행성, 오락 및 휴식, 대인관계유지의 이용 동기는 면대면 커뮤니케이션과 긍정적인 유의미한 상관관계를 보였으며 자기확인 및 유행성과 지식 및 정보획득의 이용 동기는 싸이월드 이용과는 부적인 상관관계가 나타났다. 이러한 연구결과를 바탕으로 시사점을 논의하였다.English Abstract: The purpose of this study is to explore users’ motives for using ‘Naver Band’, a leading closed-type social networking service (SNS) in Korea, and the relationships between Naver Band and existing SNSs (e.g., Facebook, Twitter, Kakao group, Cyworld, and Online Community) and face-to-face conversation among family members, based on the uses and gratifications approach and media displacement hypothesis. Online survey was conducted, and 208 data points for Naver Band users were analyzed. The main results of this study are as follows. (1) Five factors are identified as the motives for using Naver Band: ‘self-confirmation/trend’, ‘obtaining information’, ‘entertainment/relaxation’, ‘social relation’, ‘bonding relationship’. (2) The use of Naver Band is related positively to the use of Kakao Group and negatively to the use of Cyworld and Online Community. (3) ‘Self-confirmation/trend’, ‘entertainment/relaxation’ and ‘bonding relationship’ motives are related positively to face-to-face communication and ‘self-confirmation/trend,’ while ‘obtaining information’ motives are related negatively to the use of Cyworld. Based on these findings, implications and directions for future research are discussed. (written in Korean)
The economics of cell phone reuse and recycling (2009)

There is widespread consensus that landfill of waste electronic and electric equipment is not an acceptable end-of-use management option. Diversion from landfill, either through voluntary or mandatory take-back and collection programs, overwhelmingly leads to the recycling of e-waste, which typically consists of the recovery of a limited number of metals. Cell phones are currently one of the few electronic products, if not the only one, that also have a thriving reuse market. In fact, more handsets are reused than recycled. Cell phones therefore offer the rare opportunity to compare closed-loop supply chains for e-waste reuse and recycling. In this paper, we examine the economics of cell phone reuse and recycling based on detailed primary data collected from reverse logistics, reuse and recycling operations in 2003 in the UK and in 2006 in the US. We show that while cell phone reuse has a healthy profit margin, handset recycling is currently a by-product of reuse.
Electrochemical-reduction-assisted assembly of ternary Ag nanoparticles/polyoxometalate/graphene nanohybrids and their activity in the electrocatalysis of oxygen reduction (2015)

Ternary Ag NPs@POM/rGO nanohybrids were synthesized by an electrochemical-reduction-assisted assembly method and had high electrocatalytic activity towards the oxygen reduction reaction.
Computer Aided Verification (2019)

The CAV 2019 open access proceedings focus on topics such as automata and timed systems; security and hyperproperties; synthesis; model checking; cyber-physical systems; machine learning; probabilistic systems and runtime techniques; numerical programs, verification; distributed systems; networks.
The Concentration of Phosphatidylethanolamine in Mitochondria Can Modulate ATP Production and Glucose Metabolism in Mice (2014)

Phosphatidylethanolamine (PE) N-methyltransferase (PEMT) catalyzes the synthesis of phosphatidylcholine (PC) in the liver. Mice lacking PEMT are protected against diet-induced obesity and insulin resistance. We investigated the role of PEMT in hepatic carbohydrate metabolism in chow-fed mice. A pyruvate tolerance test revealed that PEMT deficiency greatly attenuated gluconeogenesis. The reduction in glucose production was specific for pyruvate; glucose production from glycerol was unaffected. Mitochondrial PC levels were lower and PE levels were higher in livers from Pemt(-/-) compared with Pemt(+/+) mice, resulting in a 33% reduction of the PC-to-PE ratio. Mitochondria from Pemt(-/-) mice were also smaller and more elongated. Activities of cytochrome c oxidase and succinate reductase were increased in mitochondria of Pemt(-/-) mice. Accordingly, ATP levels in hepatocytes from Pemt(-/-) mice were double that in Pemt(+/+) hepatocytes. We observed a strong correlation between mitochondrial PC-to-PE ratio and cellular ATP levels in hepatoma cells that expressed various amounts of PEMT. Moreover, mitochondrial respiration was increased in cells lacking PEMT. In the absence of PEMT, changes in mitochondrial phospholipids caused a shift of pyruvate toward decarboxylation and energy production away from the carboxylation pathway that leads to glucose production.
Frozen Cells and Bits: Cryoelectronics Advances Biopreservation (2013)

With few exceptions, electronic components are rated by their manufacturers to -40 °C (sometimes -55 °C). The operation of electronic components, circuits, and systems at much lower temperatures is called cold electronics, cryogenic electronics, low-temperature electronics, or cryoelectronics. Although not all electronics components are usable at low temperatures, electronic devices and circuits have been operated all the way down to a few degrees above absolute zero (0 K, -273 °C).
The Indolizidine Alkaloids (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Indolizidine AlkaloidsEmery GellertCite this: J. Nat. Prod. 1982, 45, 1, 50–73Publication Date (Print):January 1, 1982Publication History Published online1 July 2004Published inissue 1 January 1982https://pubs.acs.org/doi/10.1021/np50019a005https://doi.org/10.1021/np50019a005research-articleACS PublicationsRequest reuse permissionsArticle Views1836Altmetric-Citations139LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Experimental investigation of magnetic gradient influence in a coaxial ECR plasma thruster (2014)

International audience
Analysis of Complete Organic Semiconductor Devices by Laser Desorption/Ionization Time‐of‐Flight Mass Spectrometry (2008)

Abstract In this contribution, it is shown that the method of laser‐desorption/ionization time‐of‐flight mass spectrometry (LDI‐TOF‐MS) is a powerful technique for analyzing complete organic devices, such as organic light‐emitting diodes (OLEDs) or organic solar cells. LDI‐TOF‐MS has the potential to analyze fully processed organic devices without special pretreatment such as dissolving the device, peeling off the metal cathode, or using additional matrix materials. Thus, devices may be analysed as they are with a minimum of measurement artefacts. It is demonstrated that the method allows an analysis of complex organic multilayer devices, their composition, and incorporated impurities. It even allows possible electrochemical reaction products caused by device degradation to be analyzed. Thus, LDI‐TOF‐MS has major advantages compared to measurements of dissolved samples. As an example, the identification of all of the materials used in a complete OLED is shown. Furthermore, a detailed chemical analysis of long‐term driven OLEDs, including the detection of degradation products, is presented. From these data, several degradation mechanisms can be distinguished.
Enteric Neuropathy: NO, SNO in AGEs (2008)

Enteric neuropathy is emerging as a central theme in a range of digestive tract pathologies. Aberrant nitric oxide (NO) signaling by cellular components of the enteric nervous system or by inappropriate processing of dietary nitrite represents potential disease factors in delayed gastric emptying, diabetic gastroparesis, hypertrophic pyloric stenosis, and in inflammatory barrier dysfunction of the gut. Exploiting the neuronal nitric oxide synthase (nNOS) system to generate NO as a form of treatment is considered an option in these clinical disorders. Here we review the transcriptional regulation of nNOS activity and its pathophysiological role in the digestive tract. We also highlight potentially novel therapeutic strategies that exploit nNOS-derived S-nitrosothiols (SNO) and advanced glycation end products (AGEs).
Self-assembly and tunable plasmonic property of gold nanoparticles on mercapto-silica microspheres (2009)

We report the self-assembly behavior and tunable plasmonic property of gold nanoparticles on the surface of mercapto-silica colloidal spheres. The mercapto-silica spheres provide a quasi two-dimensional surface for nanoparticle immobilization through the strong gold–thiol interactions, making it convenient to control the interparticle separation by varying both the length of the capping ligands and the molar ratio of gold nanoparticles to the supporting mercapto-silica microspheres. With the ability to fine tune the interparticle separation and consequently the strength of the electromagnetic coupling, we demonstrate a high degree of control over the plasmon resonance property of the resulting composite microspheres. The colloidal form of the assembled nanostructures promises broad applications in which tailored plasmonic property and solution dispersibility are required.