gebhart/patrepeval huggingface dataset:
Partial proteolysis as a probe of the conformation of the gamma subunit in activated soluble and membrane-bound chloroplast coupling factor 1. (1985)

Treatments that enhance the latent ATPase activity of the chloroplast coupling factor (CF1) also induce hypersensitivity of the gamma subunit toward trypsin. A number of different gamma subunit cleavage products are formed (Moroney, J. V., and McCarty, R. E. (1982) J. Biol. Chem. 257, 5910-5914). We have compared the gamma cleavage products of membrane-bound and isolated CF1, activated either by reduction of the gamma disulfide bond or by removal of the epsilon subunit. The gamma subunit of isolated CF1 lacking the epsilon subunit was cleaved to a 27,000-Da species. The same cleavage site became exposed following energy-dependent conformational changes in the membrane-bound enzyme. Activation by reduction of the gamma disulfide bond also exposed this site. However, the gamma subunit of reduced CF1 was cleaved rapidly at an additional site and trypsin treatment gave rise to a 25,000-Da gamma species. The small peptide generated by the second cleavage contains one of the cysteinyl residues of the reduced disulfide bridge of gamma. This peptide dissociates from the enzyme and can be isolated by gel filtration. The close proximity of the trypsin cleavage sites to the disulfide bond of gamma is discussed with respect to the effects of tryptic cleavage on the ATPase activity of CF1. The data indicate that structural changes in a limited region of the gamma subunit strongly influence the catalytic properties of both soluble and membrane-bound CF1.
Recent trends in numerical simulation of three-dimensional sheet forming processes (2003)

The numerical method of analysis plays a key role in simulation of sheet metal forming processes for design innovation through virtual manufacturing. Recently, important advances in research and development of the sheet metal forming processes have been made by many scientists and engineers. This paper covers general issues in sheet metal forming but deals with the most challenging subjects including finite element (FE) techniques, springback, hydroforming and process design. Furthermore, the results of the proposed benchmark problems in NUMISHEET 2002 with both experiments and simulation results will be discussed.
Enhancement of photocurrent in epitaxial lift-off thin-film GaInNAsSb solar cells due to light-confinement structure (2018)

This work focuses on the characterization of GaInNAsSb solar cells whose substrates are removed via the epitaxial lift-off (ELO) technique. As a result of the substrate removal, increases in the photocurrent and the interference feature were clearly observed. This is clear evidence of the lightconfinement effect, whereby some of the unabsorbed photons at the rear metal contact were reflected back towards the front side of the ELO thinfilm cell. We successfully demonstrated that the ELO technique can be applied for the GaInNAsSb cell, and the light management should add flexibility in designing the cell structures.
High-resolution non-contrast free-breathing coronary cardiovascular magnetic resonance angiography for detection of coronary artery disease: validation against invasive coronary angiography (2022)

Coronary artery disease (CAD) is the single most common cause of death worldwide. Recent technological developments with coronary cardiovascular magnetic resonance angiography (CCMRA) allow high-resolution free-breathing imaging of the coronary arteries at submillimeter resolution without contrast in a predictable scan time of ~ 10 min. The objective of this study was to determine the diagnostic accuracy of high-resolution CCMRA for CAD detection against the gold standard of invasive coronary angiography (ICA). Forty-five patients (15 female, 62 ± 10 years) with suspected CAD underwent sub-millimeter-resolution (0.6 mm3) non-contrast CCMRA at 1.5T in this prospective clinical study from 2019–2020. Prior to CCMR, patients were given an intravenous beta blockers to optimize heart rate control and sublingual glyceryl trinitrate to promote coronary vasodilation. Obstructive CAD was defined by lesions with ≥ 50% stenosis by quantitative coronary angiography on ICA. The mean duration of image acquisition was 10.4 ± 2.1 min. On a per patient analysis, the sensitivity, specificity, positive predictive value and negative predictive value (95% confidence intervals) were 95% (75–100), 54% (36–71), 60% (42–75) and 93% (70–100), respectively. On a per vessel analysis the sensitivity, specificity, positive predictive value and negative predictive value (95% confidence intervals) were 80% (63–91), 83% (77–88), 49% (36–63) and 95% (90–98), respectively. As an important step towards clinical translation, we demonstrated a good diagnostic accuracy for CAD detection using high-resolution CCMRA, with high sensitivity and negative predictive value. The positive predictive value is moderate, and combination with CMR stress perfusion may improve the diagnostic accuracy. Future multicenter evaluation is now required.
Explanation of high-temperature superconductivity without cuprate planes (2002)

Abstract The superconducting hole condensate resides in the SrO planes, or in the BaO planes, or in the interstitial regions of high-temperature perovskite superconductors, depending upon the crystal structure. Supporting evidence includes the following: firstly, PrBa2Cu3O7 superconducts in its BaO layers, and not in its cuprate planes; secondly, the similarity of the layer charges for YBa2Cu3Ox and PrBa2Cu3Ox indicates that both materials superconduct in their BaO layers; thirdly, Gd2-zCezSr2Cu2TiO10, Pr2-zCezSr2Cu2NbO10 and Eu2-zCezSr2Cu2TiO10 all superconduct in their SrO layers, and not in their cuprate planes; and fourthly, the superconducting hole condensate for Cu-doped Sr2YRuO6 (a material with no cuprate planes to better than 1%) must reside in its SrO layers.
The Irish Anaesthetic and Recovery Nurses Association (IARNA). 15 November 2003; Killarney, Eire (2004)

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Mechanism of ion exchange in crystalline zirconium phosphate. II. Lithium ion exchange of .alpha.-zirconium phosphate (1970)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMechanism of ion exchange in crystalline zirconium phosphate. II. Lithium ion exchange of .alpha.-zirconium phosphateAbraham Clearfield and J. TroupCite this: J. Phys. Chem. 1970, 74, 2, 314–317Publication Date (Print):January 1, 1970Publication History Published online1 May 2002Published inissue 1 January 1970https://pubs.acs.org/doi/10.1021/j100697a015https://doi.org/10.1021/j100697a015research-articleACS PublicationsRequest reuse permissionsArticle Views260Altmetric-Citations34LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Complete Transvaginal NOTES Nephrectomy Using Magnetically Anchored Instrumentation (2009)

NOTES nephrectomy using MAGS instrumentation is feasible. We believe this approach improves shortcomings of previously reported NOTES nephrectomies in that triangulation, instrument fidelity, and visualization are preserved while hilar ligation is performed using a conventional stapler without need for additional transabdominal trocars.
The Origin of Photoluminescence from Oxygen Precipitates Nucleated at Low Temperature in Semiconductor Silicon (2004)

The nucleation process of oxygen precipitates in silicon at 650 degreesC was investigated using photoluminescence (PL) measurements, which are demonstrated to provide a highly sensitive tool for the characterization of precipitates differing in structure and shape. The results of this study were first analyzed from a thermodynamic and kinetic point of view in order to explain the effect of minute differences in oxygen concentration on the PL spectra, which indicates that two kinds of nanometric oxides coexist in dynamic equilibrium. Then a hypothesis is advanced about the origin of the oxygen-induced PL bands, which is explained in terms of carrier confinement effects induced by the strain at oxide precipitates. (C) 2004 The Electrochemical Society.
Different precore/core mutations of hepatitis B interact with, limit, or favor liver fibrosis severity (2016)

Patients with the A1762T/G1764A mutation have a higher risk of severe fibrosis. The G1899A mutation is a protective factor against severe fibrosis that counteracted the deleterious effect of the A1762T/G1764A mutation. Finally, host phenotypic and HBV genotypic markers independently predict fibrosis severity.
Defensins block the release but not the processing of IL-1beta and IL-18 from human monocytes (38.13) (2009)

Abstract We have previously shown that human defensins can block the release of IL-1beta from LPS-primed human monocytes stimulated with ATP. The objective of this study is to determine whether defensins can inhibit the release IL-1beta and IL-18 from LPS-primed human monocytes stimulated with other inflammasome activators. LPS-activated (20 ng/ml, 2 h), 35S-methionine-labeled (1 h) human monocytes were treated with human defensin HD-5 in the presence or absence of ATP, monosodium urate (MSU), nigericin (Nig) for 90 min. Media and cell-associated fractions were harvested separately. IL-1beta was recovered from each by immunoprecipitation and caspase-1 was examined by western blot analysis. Mature IL-1beta and active caspase-1 were detected in the cytosol fraction from cells treated with HD-5. Thus, HD-5 blocked the release of mature IL-1beta from cells treated with ATP, MSU, or Nig. However, HD-5 did not inhibit ATP-, MSU-, or Nig-induced caspase-1 activation and processing of IL-1beta. In addition, HD-5 also blocked the release of IL-18 from LPS-primed human monocytes stimulated with ATP. To our knowledge, HD-5 is the first known endogenous inhibitor of IL-1beta and IL-18 release. These studies suggest that processing and release of IL-1beta are independent processes.
NVSim: A Circuit-Level Performance, Energy, and Area Model for Emerging Nonvolatile Memory (2012)

Various new nonvolatile memory (NVM) technologies have emerged recently. Among all the investigated new NVM candidate technologies, spin-torque-transfer memory (STT-RAM, or MRAM), phase-change random-access memory (PCRAM), and resistive random-access memory (ReRAM) are regarded as the most promising candidates. As the ultimate goal of this NVM research is to deploy them into multiple levels in the memory hierarchy, it is necessary to explore the wide NVM design space and find the proper implementation at different memory hierarchy levels from highly latency-optimized caches to highly density- optimized secondary storage. While abundant tools are available as SRAM/DRAM design assistants, similar tools for NVM designs are currently missing. Thus, in this paper, we develop NVSim, a circuit-level model for NVM performance, energy, and area estimation, which supports various NVM technologies, including STT-RAM, PCRAM, ReRAM, and legacy NAND Flash. NVSim is successfully validated against industrial NVM prototypes, and it is expected to help boost architecture-level NVM-related studies.
Effect of an acidulated fluoride etchant on bonding between titanium and two luting materials (2005)

Adhesive bonding between resin and titanium is useful for resin-bonded prostheses. The purpose of this study was to investigate the efficacy of an etchant, consisting of ammonium hydrogen fluoride (AHF) and phosphoric acid (PA), in titanium bonding. Cast specimens of commercially pure titanium were air-abraded with alumina and etched for 30 s, after which a primer (ALP) was applied. An acrylic rod was bonded to the specimen with one of the two luting agents being examined (Super-Bond QUICK and Panavia F2.0). Shear bond strengths were determined following 10,000 thermocycles. When Panavia F2.0 was applied, neither the etchant nor the ALP primer showed significant effect on bond strength. The postthermocycling bond strength of Super-Bond QUICK was significantly improved with the use of an etchant and ALP primer. Although microscopic observation revealed that considerable numbers of submicron pits were created on the specimens etched using AHF with PA, no significant difference in bond strength was detected in the application of AHF, with or without PA. The present findings suggested that the improved bonding durability was due to the micromechanical retention between the resin and the microscopically roughened titanium surface.
ChemInform Abstract: Highly Enantiopure C1‐Symmetric cis‐Piperidine‐3,5‐dimethanol Monoacetates by Enzymatic Asymmetrization. (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Source polarization (2010)

The notion of source polarization is introduced and investigated. This complements the earlier work on channel polarization. An application to Slepian-Wolf coding is also considered. The paper is restricted to the case of binary alphabets. Extension of results to non-binary alphabets is discussed briefly.
Rat Heterotopic Heart Transplantation Model to Investigate Unloading-Induced Myocardial Remodeling (2016)

Unloading of the failing left ventricle in order to achieve myocardial reverse remodeling and improvement of contractile function has been developed as a strategy with the increasing frequency of implantation of left ventricular assist devices in clinical practice. But, reverse remodeling remains an elusive target, with high variability and exact mechanisms still largely unclear. The small animal model of heterotopic heart transplantation (hHTX) in rodents has been widely implemented to study the effects of complete and partial unloading on cardiac failing and non-failing tissue to better understand the structural and molecular changes that underlie myocardial recovery. We herein review the current knowledge on the effects of volume unloading the left ventricle <i>via</i> different methods of hHTX in rats, differentiating between changes that contribute to functional recovery and adverse effects observed in unloaded myocardium. We focus on methodological aspects of heterotopic transplantation, which increase the correlation between the animal model and the setting of the failing unloaded human heart. Last, but not least, we describe the late use of sophisticated techniques to acquire data, such as small animal MRI and catheterization, as well as ways to assess unloaded hearts under "reloaded" conditions. While giving regard to certain limitations, heterotopic rat heart transplantation certainly represents the crucial model to mimic unloading-induced changes in the heart and as such the intricacies and challenges deserve highest consideration. Careful translational research will further improve our knowledge of the reverse remodeling process and how to potentiate its effect in order to achieve recovery of contractile function in more patients.
Intranasal Inoculation of Bordetella Bronchiseptica in Mice Induces Long‐Lasting Antibody and T‐Cell Mediated Immune Responses (1996)

Humoral and cellular immune responses were analysed in mice inoculated intranasally with Bordetella bronchiseptica. After infection, the number of bacteria that colonized the respiratory tract of the mice increased during the first day and decreased thereafter. Total IgG levels increased as early as 14 days after infection and decreased with time after infection, whereas total IgA and IgM levels were lower but remained stable. Specific antibodies to the bacteria were mainly IgG2a and IgA and persisted up to 10 months after infection. Some of these specific antibodies were directed against adenylate cyclase-haemolysin, the bacterial factor that had been shown to be necessary for initiation of infection. The proliferation of Bordetella bronchiseptica-reactive spleen cells occurred during the acute phase of infection. T cells from infected mice produced increasing amounts of IFN gamma and IL-2 after infection. Although very low levels of IL-10 were produced, no IL-4 was detected after bacterial stimulation in vitro. These results suggest that Bordetella bronchiseptica infection induces primarily a Th1-type T-cell response. Importantly, the authors demonstrated that antibody and T-cell responses directed against bacterial determinants of the virulent strain and to purified adenylate cyclase-haemolysin were long-lasting. This observation could be due to the fact that Bordetella bronchiseptica may persist intracellularly in the host as it was demonstrated in vitro.
Review of Tank Lay-Up Status at US Department of Energy Radioactive Waste Tank Sites (2002)

During fiscal year (FY) 2001 as part of a Tanks Focus Area strategic intiative, tank lay-up options were developed and evaluated for the two high-level waste (HLW) storage tanks at the West Valley Demonstration Project. As follow-on task, a list of key waste tank contacts throughout the US Department of Energy complex was developed. Visits were then made to the primary DOE sites with radioactive waste storage tanks to discuss the concept and applicablility of tank lay-up. This report documents the results of individual discussions with tank closure staff at the four DOE Sites concerning tank closure status and plans as well as lay-up options and activities.
Supplementary Table 2 from Association of AR-V7 and Prostate-Specific Antigen RNA Levels in Blood with Efficacy of Abiraterone Acetate and Enzalutamide Treatment in Men with Prostate Cancer (2023)

&lt;p&gt;Time to treatment failure (TTF) and overall survival (OS) in a subgroup of patients with blood draw within 6 months prior to therapy initiation&lt;/p&gt;
Design of a Rehabilitation Exoskeleton with Impedance Control: First Experiments (2021)

International audience
Epigenetic master regulators HDAC1 and HDAC5 control pathobiont Enterobacteria colonization in ileal mucosa of Crohn’s disease patients (2022)

Adherent-invasive Escherichia coli (AIEC), which abnormally colonize the ileal mucosa of Crohn’s disease (CD) patients, are known to contribute to the etiopathogenesis of CD. Molecular mechanisms favoring AIEC ileal colonization have not been completely characterized yet. The aim of this study was to investigate whether epigenetic regulators histone deacetylases (HDAC) expression in intestinal epithelial cells of CD patients regulate Enterobacteria and AIEC encroachment to intestinal mucosa. HDAC were inhibited in vitro and in CEABAC10 mice to decipher their involvement in the entry of AIEC within host cells. CD ileal samples from the REMIND cohort were used to study the relationship between HDAC expression level and Enterobacteria/AIEC colonization in patients. Mice were fed a westernized diet and orally challenged with AIEC to determine the impact of diet on HDAC expression. Global level of acetylated histone H3 is higher in patients colonized by AIEC bacteria compared to patients non-colonized by Enterobacteria and HDAC inhibition-mediated H3 hyperacetylation promotes the entry of AIEC bacteria within intestinal epithelial cells. HDAC1 and HDAC5 are central and antagonistic in the regulation of AIEC entry within host cells in vitro, in mouse models and in ileal mucosa of CD patients. In mice fed a western-type diet, AIEC infection decreases HDAC1 expression, inducing H3 hyperacetylation to favor their own colonization. CD patients under a western diet are more prone to be colonized by AIEC bacteria as such a diet affects intestinal homeostasis, enables AIEC access to intestinal mucosa where they then manipulate host-epigenome to their advantage.
ChemInform Abstract: Ozonolysis of Alkenes and Reactions of Polyfunctionalized Compounds. Part 47. Synthesis of Diethers of 2,6‐Dimethyl‐2(E)‐octene‐1,8‐diol Possessing Juvenoid Activity. (1993)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A novel approach of fingerprint recognition based on multilinear ICA (2009)

Motivated by the reported out performance in the fingerprint recognition thesises of PCA by ICA in the linear case where only a single factor is allowed to vary, and the outperformance of PCA by FET when multiple factors are allowed to vary, it is natural to ask whether there a multilinear generalization of ICA and if its performance is better than the other two methods. In this paper, We have presented a multilinear algebraic framework for fingerprint image recognition, which employs a tensor (N-mode) extension of the conventional matrix SVD. We also introduced a multilinear projection algorithm for fingerprint recognition, which projects an unlabeled test image into the N constituent mode spaces to infer its mode label-sperson, finger, type.
Wearable Sensors and Smart Devices to Monitor Rehabilitation Parameters and Sports Performance: An Overview (2023)

A quantitative evaluation of kinetic parameters, the joint's range of motion, heart rate, and breathing rate, can be employed in sports performance tracking and rehabilitation monitoring following injuries or surgical operations. However, many of the current detection systems are expensive and designed for clinical use, requiring the presence of a physician and medical staff to assist users in the device's positioning and measurements. The goal of wearable sensors is to overcome the limitations of current devices, enabling the acquisition of a user's vital signs directly from the body in an accurate and non-invasive way. In sports activities, wearable sensors allow athletes to monitor performance and body movements objectively, going beyond the coach's subjective evaluation limits. The main goal of this review paper is to provide a comprehensive overview of wearable technologies and sensing systems to detect and monitor the physiological parameters of patients during post-operative rehabilitation and athletes' training, and to present evidence that supports the efficacy of this technology for healthcare applications. First, a classification of the human physiological parameters acquired from the human body by sensors attached to sensitive skin locations or worn as a part of garments is introduced, carrying important feedback on the user's health status. Then, a detailed description of the electromechanical transduction mechanisms allows a comparison of the technologies used in wearable applications to monitor sports and rehabilitation activities. This paves the way for an analysis of wearable technologies, providing a comprehensive comparison of the current state of the art of available sensors and systems. Comparative and statistical analyses are provided to point out useful insights for defining the best technologies and solutions for monitoring body movements. Lastly, the presented review is compared with similar ones reported in the literature to highlight its strengths and novelties.