gebhart/patrepeval huggingface dataset:
Carbon dot aggregates as an alternative to gold nanoparticles for the laser-induced opening of microchamber arrays (2018)

Carbon dots (CDs) are usually used as an alternative to other fluorescent nanoparticles. Apart from fluorescence, CDs also have other important properties for use in composite materials, first of all their ability to absorb light energy and convert it into heat. In our work, for the first time, CDs have been proposed as an alternative to gold nanostructures for harvesting light energy, which results in the opening of polymer-based containers with biologically active compounds. In this paper, we propose a method for the synthesis of polylactic acid microchamber arrays with embedded CDs. A comparative analysis was made of the damage to microchambers functionalized with gold nanorods and with CD aggregates, depending on the wavelength and power of the laser used. The release of fluorescent cargo from the microchamber arrays with CD aggregates under laser exposure was demonstrated.
Dentin Phosphoprotein Binds Annexin 2 and Is Involved in Calcium Transport in Rat Kidney Ureteric Bud Cells (2013)

Dentin phosphoprotein (DPP) is the most abundant noncollagenous protein in the dentin, where it plays a major role in the mineralization of dentin. However, we and others have shown that in addition to being present in the dentin, DPP is also present in nonmineralizing tissues like the kidney, lung, and salivary glands, where it conceivably has other functions such as in calcium transport. Because annexins have been implicated as calcium transporters, we examined the relationships between DPP and annexins. In this report, we show that DPP binds to annexin 2 and 6 present in a rat ureteric bud cell line (RUB1). Immunofluorescence studies show that annexin 2 and DPP colocalize in these cells. In addition, DPP and annexin 2 colocalize in the ureteric bud branches of embryonic metanephric kidney. In the RUB1 cells and ureteric bud branches of embryonic kidney, colocalization was restricted to the cell membrane. Studies on calcium influx into RUB cells show that in the presence of anti-DPP, there was a 40% reduction of calcium influx into these cells. We postulate that DPP has different functions in the kidney as compared with the odontoblasts. In the odontoblasts, its primary function is in the extracellular mineralization of dentin, whereas in the kidney it may participate in calcium transport.
Intermediate bus architectures: A practical review (2013)

Three basic intermediate bus architectures are reviewed for electronic power system developers. Salient features for practical system development are then discussed in detail, including power efficiency, regulation, component selection, load cross regulation, and board thermal flux density. The double regulated intermediate bus architecture has the best overall efficiency, regulation, size, and thermal performance.
In search of causal variants: refining disease association signals using cross-population contrasts (2008)

Filtering out SNPs that demonstrate cross-population heterogeneity enriches for variants more likely to be important and causative. Our approach provides an important and effective tool to help interpret results from the many GWA studies now underway.
Electrochemical Behavior of Surface-Fluorinated Natural Graphite in Propylene Carbonate-Containing Solvent (2007)

Surface fluorination of natural-graphite samples with average particle sizes of 5, 10, and (abbreviated to , , and ) was performed by at 200 and for and electrochemical properties of surface-fluorinated natural-graphite samples were investigated in –ethylene carbonate (EC)/diethyl carbonate (DEC)/propylene carbonate (PC) (1:1:1 in volume). Surface fluorine concentrations were in the range of 11.1–15.3 and for natural-graphite samples fluorinated at 200 and 300°C, respectively, for three natural-graphite samples. The surface areas of and were only slightly increased by fluorination, while the increase in surface area was large in the case of . However, the increase in surface disorder by fluorination was larger for and than for . Electrochemical reduction of PC on and was highly reduced by surface fluorination, which led to a large increase in first coulombic efficiencies. The increase in first coulombic efficiencies for surface-fluorinated and is attributed to the increase in their surface disorder and probably actual electrode area by fluorination.
The homeobox gene Gsx2 controls the timing of oligodendroglial fate specification in mouse lateral ganglionic eminence progenitors (2013)

The homeobox gene Gsx2 has previously been shown to be required for the specification of distinct neuronal subtypes derived from lateral ganglionic eminence (LGE) progenitors at specific embryonic time points. However, its role in the subsequent generation of oligodendrocytes from these progenitors remains unclear. We have utilized conditional gain-of-function and loss-of-function approaches in order to elucidate the role of Gsx2 in the switch between neurogenesis and oligodendrogenesis within the embryonic ventral telencephalon. In the absence of Gsx2 expression, an increase in oligodendrocyte precursor cells (OPCs) with a concomitant decrease in neurogenesis is observed in the subventricular zone of the LGE at mid-stages of embryogenesis (i.e. E12.5-15.5), which subsequently leads to an increased number of Gsx2-derived OPCs within the adjacent mantle regions of the cortex before birth at E18.5. Moreover, using Olig2(cre) to conditionally inactivate Gsx2 throughout the ventral telencephalon with the exception of the dorsal (d)LGE, we found that the increase in cortical OPCs in Gsx2 germline mutants are derived from dLGE progenitors. We also show that Ascl1 is required for the expansion of these dLGE-derived OPCs in the cortex of Gsx2 mutants. Complementing these results, gain-of-function experiments in which Gsx2 was expressed throughout most of the late-stage embryonic telencephalon (i.e. E15.5-18.5) result in a significant decrease in the number of cortical OPCs. These results support the notion that high levels of Gsx2 suppress OPC specification in dLGE progenitors and that its downregulation is required for the transition from neurogenesis to oligodendrogenesis.
Mobile telecommunications evolution in Southeastern Europe (2005)

Over the last few years the mobile market in South East Europe (SEE) has experienced a rapid growth in terms of operators and penetration rates of mobile telephony. This is due to the fact that wireless telephony has a cost comparable to fixed and it is easier to be established in comparison with fixed. Moreover, the countries of SEE hope that through mobile telephony they will be able to decrease the digital gap between them and the European Union countries. An overview of the mobile telecommunications evolution in SEE countries is analyzed in this article.
Association of PSA and number of cores positive with likelihood of adverse pathology at radical prostatectomy based on a 17-gene expression assay. (2016)

e16570 Background: The overtreatment of prostate cancer and underutilization of active surveillance in men with Gleason 6 (GS6) cancer stems from uncertainty with current risk instruments such as volume of GS6 tumor and PSA > 10 ng/ml. The 17-gene biopsy-based RT-PCR assay has been analytically and clinically validated as an independent predictor of adverse pathology at prostatectomy. We report on the impact of volume of GS6 disease and PSA at biopsy on the biologic aggressiveness of the disease as measured by the assay (GPS). Methods: 1,055 pathology reports received at Genomic Health, Inc. were reviewed to record GS, number of cores positive, and PSA. GPS was calculated from a single block for each case with an associated path report using the validated algorithm of 12 cancer and 5 reference genes; median GPS was calculated for each sub-group ( ≤ 2 cores positive, > 4 cores positive, PSA < 4 ng/ml, PSA 4-10 ng/ml, PSA > 10 ng/ml). Results: 803 cases (76%) were submitted as GS6. 66% of cases contained 12 cores, 4% of cases had < 12 cores and 30% of cases had > 12 cores. The median GPS for GS6 cases with ≤ 2 cores positive was 24 (IQR 16.5 to 30.5) compared to a median GPS of 26 (IQR 20 to 34) for 4 or more cores positive. After incorporating the GPS, risk refinement, a change in categorical risk assessment was seen in 24% of cases with ≤ 2 cores positive and 26% of cases with > 4 cores positive. 294 of cases with GS6 also reported a PSA value. 25% of GS6 cases had a PSA < 4, 67% were 4-10, and 8% were > 10 ng/ml. No significant correlation was seen between PSA and GPS. The median GPS values for cases with a PSA < 4, 4-10, and > 10 were 25(IQR 16-31), 24(IQR 17-32), and 25(IQR 17-39), respectively. Risk refinement following GPS occurred in 48% of cases with a PSA < 10 and 23% with a PSA > 10. Conclusions: The GPS results highlight the broad spectrum of tumor aggressiveness in a series of 803 biopsies containing GS6 independent of % cores positive and PSA. The degree of risk refinement among all GS6 cases independent of tumor volume or PSA highlight the utility of the GPS to provide predictive information beyond traditional clinical variables used for risk stratification in the management of men with GS 6 disease at the time of diagnosis.
Novel absolute linear displacement sensor utilizing giant magnetoresistance elements (1997)

A novel concept for an absolute linear displacement sensor utilizing giant magnetoresistance elements is introduced. This device is based on the division of a magnetically soft layer of a spin-valve device into two antiparallel magnetic domains. The total resistance of the spin valve varies linearly with displacement of the domain wall because of different resistances of the aligned and antialigned magnetic states of the spin valve. Domain-wall translation is achieved by the use of a magnetic wall “trap” generated by permanent magnets. Displacement is thus related directly to the device resistance. Position resolution to date is on the order of 10 μm over ranges of approximately 2 cm and on the order of a micron over reduced ranges. Magnetic hysteresis yields backlash on the order of tens of microns.
[Effect of an extract containing esterol on plasma cholesterol and oxidants]. (1998)

16 patients with hypercholesterolemia were treated with an extract of alpha-alpha leaves (esterol) while on a low-fat, low-cholesterol diet. Esterol is believed to inhibit the absorption of cholesterol and bile acids and may interfere with the absorption of essential nutrients. As oxidative modification of lipoproteins is required for the process of atherosclerosis, plasma antioxidant vitamins were followed. After 4 months of treatment, plasma cholesterol decreased by 10% from 282 to 250 mg/dl (p < 0.001) and LDL cholesterol by 13%, from 203 to 177 mg/dl (p < 0.001). Plasma antioxidant vitamins E, A and beta-carotene were unchanged. Thus, esterol has a cholesterol-lowering effect but apparently does not lower fat-soluble, plasma antioxidant vitamins. Both cholesterol-lowering and plasma antioxidant vitamins are important for the primary prevention of coronary artery disease in hypercholesterolemia.
A “naked eye” and ratiometric fluorescent chemosensor for rapid detection of F− based on combination of desilylation reaction and excited-state proton transfer (2011)

A colorimetric and ratiometric fluorescent chemosensor for F(-) has been prepared, which is based on combination of desilylation reaction and excited-state proton transfer from the desilylation product to F(-). The sensor exhibits rapid response, excellent selectivity and sensitivity to F(-).
Mind from Matter? An Essay on Evolutionary Epistemology (1987)

Introduction and overview Evolution of the cosmos Evolution of life Beginnings of perceptions: species Evolution of genomes Evolution of man Evolution of the brain Vision Perception Cognition Causality, time, space Numbers Infinity: logical paradoxes Decidability Geometry, astronomy, Newtonian mechanics Relativity theory Quantum theory Complimentarity The Cartesian cut Language Summing up.
The System Ammonium Fluoride-Hydrogen Fluoride-Water at 0 and -20° (1963)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe System Ammonium Fluoride-Hydrogen Fluoride-Water at 0 and -20°John P. Buettner and Albert W. JacheCite this: Inorg. Chem. 1963, 2, 1, 19–22Publication Date (Print):February 1, 1963Publication History Published online1 May 2002Published inissue 1 February 1963https://pubs.acs.org/doi/10.1021/ic50005a005https://doi.org/10.1021/ic50005a005research-articleACS PublicationsRequest reuse permissionsArticle Views132Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Perception-Informed Autonomous Environment Augmentation with Modular Robots (2018)

We present a system enabling a modular robot to autonomously build structures in order to accomplish high-level tasks. Building structures allows the robot to surmount large obstacles, expanding the set of tasks it can perform. This addresses a common weakness of modular robot systems, which often struggle to traverse large obstacles. This paper presents the hardware, perception, and planning tools that comprise our system. An environment characterization algorithm identifies features in the environment that can be augmented to create a path between two disconnected regions of the environment. Specially-designed building blocks enable the robot to create structures that can augment the environment to make obstacles traversable. A high-level planner reasons about the task, robot locomotion capabilities, and environment to decide if and where to augment the environment in order to perform the desired task. We validate our system in hardware experiments.
PHASON STRAIN IN QUASICRYSTALS (1986)

Phonons, phasons and dislocations in a quasicrystal are interpreted as distortions and rearrangements of unit cells. The relation between the unit cell picture these defects and a simple density wave picture is demonstrated. Phason strain and relaxation is discussed in the context of the unit cell picture.
Real time control of a fin loading system (2016)

Fin actuation systems are one of the most essential parts of missiles since they actuate the fins and consequently provide missiles to carry out certain tasks during their mission. The designed control algorithm for the fin actuation system (FAS) must cope with the disturbances where the most prominent of them are the aerodynamic loads on the fins. Even though the control algorithm can be tested by computer simulations one may not be sure if the system works as required. Hence, the realistic aerodynamic loads must be applied to the fin shaft. In this study, a fin loading system (FLS) will be presented and the torque model of a fin loading system is derived. Omitting nonlinearities due to dead-zone and viscous friction, the parameters of the FLS are obtained by system identification technique using a predefined system structure. Since, there are modelling inaccuracies and external disturbances, Sliding Mode Control (SMC) approach is chosen as it is known to be robust to matched uncertainties once it reaches to the sliding hyper-plane. SMC is shown to have good tracking performance and disturbance rejection property in real time application in the presence of modelling inaccuracies and high disturbances due to fins movement.
Self-Retained Internal Ureteral Stents: A New Approach (1978)

Definitive surgical treatment of ureteral obstruction may not be appropriate in patients with advanced malignancy, complex benign ureteral disease or even simple obstructive disease accompanied by unacceptable operative risk. Endoscopic placement of self-retained internal ureteral catheters (stents) offers satisfactory relief for many of these patients. A new 6F pigtail ureteral stent and placement technique are described. These stents are placed easily, effective and well tolerated for short-term drainage in selected patients with ureteral obstruction.
PORTABLE AND SELF-POWERED PAPER-BASED ELECTROPHORETIC MICROFLUIDIC DEVICES (2013)

Paper-based microfluidics provides a promising platform for medical diagnostics and environmental monitoring. Among many diagnostic or analytical applications, the separation of chemicals is of great importance and readily achievable with electrophoresis, but traditional electrophoretic devices are generally large and require bulky external power supplies[1]. To miniaturize traditional electrophoretic devices for point- of-care service, we fabricated a selfpowered microfluidic device to demonstrate the possibility of paper-based devices for inexpensive separation of chemicals.
Heat Exchanger Design with Topology Optimization (2017)

Topology optimization is proving to be a valuable design tool for physical systems, especially for structural systems. However, its application in the field of heat transfer is less evident but is constantly progressing. In this chapter, we would like to introduce topology optimization in the context of heat exchanger design to the general reader. We also provide a chronological review of available literature to see the current progress of topology optimization in the field of heat transfer and heat exchanger design. We expect that topology optimization will prove to be a valuable tool in heat exchanger design for the coming years.
Biomedical Utility of 1.34 μm Nd: YAG Laser Radiation (1981)

Absorption of the 1.34 μm Nd: YAG laser radiation in whole human blood and animal tissues is compared with 1.06, μm Nd: YAG and argon laser radiation. Absorption coefficients are determined and the biomedical utility of the 1.34 μm wavelength is evaluated.
A two-regime analysis of the COVID-19 vaccine distribution process (2023)

Purpose The purpose of this paper is to develop a framework to evaluate and assess the performance of the COVID-19 vaccine distribution process that is sensitive to the unique supply-side and demand-side constraints exhibited in the US vaccine rollout. Design/methodology/approach A queuing framework that operates under two distinct regimes is formulated to analyze service rates that represent system capacity to vaccinate (under the first regime) and hesitancy-induced throughput (under the second regime). These supply- and hesitancy-constrained regimes form the focus of the present paper, as the former reflects the inherent ability of the nation in its various jurisdictions to mobilize, whereas the latter reflects a critical area for public policy to protect the population’s overall health and safety. Findings The two-regime framework analysis provides insights into the capacity to vaccinate and hesitancy-constrained demand, which is found to vary across the country primarily by politics and region. The framework also allows analysis of the end-to-end supply chain, where it is found that the ability to vaccinate was likely constrained by last-mile administration issues, rather than the capacity of the manufacturing and transportation steps of the supply chain. Originality/value This study presents a new framework to consider end-to-end supply chains as dynamic systems that exhibit different regimes because of unique supply- and demand-side characteristics and estimate rollout capacity and underlying determinants at the national, state and county levels.
Self-sensing coaxial muscle fibers with bi-lengthwise actuation (2021)

Artificial muscle fibers as a promising biomimetic actuator are needed for such applications as smart soft robots, muscle function restoration, and physical augmentation. Currently developed artificial muscle fibers have shown attractive performance in contractile and torsional actuations. However, the contractile muscle fibers do not have the capability of stimulus-responsive elongation, and real-time identifying their contractile position by themselves is still challenging. We report herein the preparation of a Ti<sub>3</sub>C<sub>2</sub>T<sub><i>x</i></sub> MXene/single walled carbon-nanotubes (SWCNTs)-coated carbon nanotube (CNT)@polydimethylsiloxane (PDMS) coaxial muscle fiber that integrates the important features of self-position sensing and bi-lengthwise actuation. The bi-lengthwise actuation is realized by utilizing the large expansion coefficient difference of PDMS in response to solvent and heat, which results in ∼5% maximum elongation by n-heptane adsorption and ∼19% maximum contraction by electric heating under the optimal conditions. Meanwhile, due to the piezoresistive effect of the MXene/SWCNTs layer, the resistance change of this coating layer is almost linearly dependent on the contraction of the coaxial muscle fiber, providing a function of real-time self-position sensing. Furthermore, an application of using a bundle of these multifunctional coaxial muscle fibers for a bionic arm has been demonstrated, which provides new insights into the design of integrated intelligent artificial muscles with synergistic multiple functions.
Sensitive detection of narrowband signals (1984)

It is pointed out that an effective search for extraterrestrial intelligence (SETI) presents a signal processing task with unusual requirements. In the first place, algorithms with a very low false alarm probability are needed. This implies, that the interpretation of noise as a signal must be rare. Secondly in a SETI, attention must be given to signals having narrow-band or pulsed features. Theoretical considerations are discussed along with aspects of pulse detector motivation, independent pulse trains and the false alarm rate, and software considerations.
Patient-reported quality of life in fibrotic interstitial lung disease: novel assessments of self-management ability and affect (2021)

<b>Patient-reported outcomes in fibrotic interstitial lung disease may be additionally predicted by novel assessments of self-management ability and affect</b> https://bit.ly/3iwP5M2.
Pricing for profitability: Give your competitors the “dog” jobs and keep the “gravy” for yourself (2003)

Abstract With apologies to Woody Hayes, three things can happen when establishing prices, and two of them are bad: You can overprice and lose a sale that would have been profitable at a lower price, or you can underprice and make an unprofitable sale. Only the third outcome is favorable: Price appropriately and make the sale as well as a profit. © 2003 Wiley Periodicals, Inc.