gebhart/patrepeval huggingface dataset:
Combustion Dynamics of Plasma-Enhanced Premixed and Nonpremixed Flames (2010)

Combustion dynamics are investigated for plasma-enhanced methane-air flames in premixed and nonpremixed configurations using a transient arc dc plasmatron. Planar laser-induced fluorescence images of hydroxyl (OH) and carbon monoxide (CO) radicals are obtained over a range of equivalence ratios (φ = 0.7 - 1.3), flow rates (6-18 LPM), and plasma powers (100-900 mA) to monitor radical propagation and in situ fuel reforming. The flow rates presented here are outside the range of normal flame stability. In the nonpremixed mode, the fuel is injected separately as a coflow around the plasma discharge, resulting in a unique two-cone flame front geometry, and the flame stability is mainly dependent on the flow dynamics. For premixed flames, partial oxidation occurs inside the chamber, resulting in higher energy conversion efficiencies, and stability is shown to be sensitive to the combustion chemistry. Both configurations are significantly influenced by in situ fuel reforming at higher plasma powers.
Kluver‐Bucy syndrome and amyotrophic lateral sclerosis (1986)

We studied a patient with amyotrophic lateral sclerosis and the Klüver-Bucy syndrome. At autopsy there was extensive degeneration of the limbic system with the brunt of the changes in the medial temporal lobe, especially the entorhinal cortex and subiculum. Degenerative changes were also seen in the substantia nigra and lower motor neurons. Morphometric and biochemical studies implied a disease process that affected small, possibly somatostatinergic, cortical neurons. These latter findings and the lobar distribution of cortical atrophy were consistent with Pick's disease, but Pick bodies and ballooned neurons were not present.
cDNA isolation and partial gene structure of the human α4(IV) collagen chain (1993)

A novel collagen IV chain, alpha 4(IV), has recently been identified in basement membranes. We describe part of the primary structure of the human alpha 4(IV) polypeptide for the first time, which has been determined by cloning and sequencing of cDNAs encoding 241 amino acid residues of the COL domain and 231 residues of the NC1 domain. We also characterized a genomic DNA fragment containing 4 exons coding for the entire NC1 domain. Among five known alpha chains of collagen IV, the alpha 4(IV) chain is distinct from the other four chains. However, it is more similar to the alpha 2(IV) chain than to the alpha 1(IV), alpha 3(IV) and alpha 5(IV) chains in terms of amino acid sequence homology, domain structure of polypeptides and exon/intron structure of the genes, suggesting the presence of two phylogenetically distinct subclasses of collagen IV alpha chains; one composed of alpha 2 and alpha 4 chains and the other of alpha 1, alpha 3 and alpha 5 chains.
Diiron Proton Reduction Catalysts Possessing Electron‐Rich and Electron‐Poor Naphthalene‐1,8‐dithiolate Ligands (2009)

The diiron complexes [Fe(2)(CO)(6)(1,8-S(2)-2,4,5,7-Cl(4)C(10)H(2))] (3), [Fe(2)(CO)(6)(1,8-S(2)C(10)H(6))] (4), and [Fe(2)(CO)(6)(1,8-S(2)-2,7-tBu(2)C(10)H(4))] (5) were synthesized in moderate yield from naphthalene-1,8-dithiols and [Fe(3)(CO)(12)]. They were characterized by IR, (1)H and (13)C NMR spectroscopy and 3 and 4 were characterized by X-ray crystallography. They contain a butterfly Fe(2)S(2) core with Fe-Fe distances of 2.529(1) (3) and 2.506(1) A (4). Cyclic voltammetry (CH(2)Cl(2)/nBu(4)PF(6)) revealed two one-electron reductions, at potentials more positive than those for the related [Fe(2)(CO)(6)(S(CH(2))(3)S)] (1), and one one-electron oxidation. The first reduction of the electron poor 3 (-1.60 V vs Fc/Fc(+)) is 240 mV more positive than the first reduction of the electron rich 5 (-1.84 V). Electrochemical studies revealed that 3-5 facilitate the proton reduction of p-toluenesulfonic acid. The rates of catalysis, with a 95% confidence limit, are 2.4+/-0.8 (1), 5.2+/-0.8 (3), 3.1+/-1.1 (4), 2.9+/-0.6 (5), and 4.5+/-0.2 h(-1) for the related [Fe(2)(CO)(6)(1,2-S(2)C(6)H(4))]. The rates were determined by bulk electrolysis at -1.70 V (Fc/Fc(+)), which correspond to an overpotential of 1.05 V for p-toluenesulfonic acid.
Oscillating electrochemical reaction in copper-containing imidazolium ionic liquids (2011)

An example of an electrochemical oscillator in ionic liquids is presented. Solutions of the ionic liquid 1-ethyl-3-methylimidazolium chloride, [C(2)mim]Cl, which contain both Cu(+) and Cu(2+) ions, show current oscillations during potentiostatic polarization. The oscillations were analyzed by the Quartz Crystal Microbalance (QCM) technique and by Electrochemical Impedance Spectroscopy (EIS). The electrochemical oscillations are of the N-NDR-type, because the low frequency end of the impedance spectrum has negative real impedances. The oscillating current leads to an oscillating growth speed of a metallic copper layer. Besides the presence of both Cu(+) and Cu(2+), the presence of chloride is a necessary, yet not a sufficient, condition for the occurrence of current oscillations. Oscillating currents were also observed for the ionic liquids 1-butyl-3-methylimidazolium chloride and 1-butyl-2,3-dimethylimidazolium chloride, but not for tributyltetradecylphosphonium chloride and N-butylpyridinium chloride.
Evaluating Fuzz Testing (2018)

Fuzz testing has enjoyed great success at discovering security critical bugs in real software. Recently, researchers have devoted significant effort to devising new fuzzing techniques, strategies, and algorithms. Such new ideas are primarily evaluated experimentally so an important question is: What experimental setup is needed to produce trustworthy results? We surveyed the recent research literature and assessed the experimental evaluations carried out by 32 fuzzing papers. We found problems in every evaluation we considered. We then performed our own extensive experimental evaluation using an existing fuzzer. Our results showed that the general problems we found in existing experimental evaluations can indeed translate to actual wrong or misleading assessments. We conclude with some guidelines that we hope will help improve experimental evaluations of fuzz testing algorithms, making reported results more robust.
Quantum Computers for High-Performance Computing (2021)

Quantum computing systems are developing rapidly as powerful solvers for a variety of real-world calculations. Traditionally, many of these same applications are solved using conventional high-performance computing (HPC) systems, which have progressed sharply through decades of hardware and software improvements. Here, we present a perspective on the motivations and challenges of pairing quantum computing systems with modern HPC infrastructure. We outline considerations and requirements for the use cases, macroarchitecture, microarchitecture, and programming models needed to integrate near-term quantum computers with HPC system, and we conclude with the expectation that such efforts are well within reach of current technology.
Supplementary Table S4 from Intracranial Efficacy of Selpercatinib in <i>RET</i> Fusion-Positive Non–Small Cell Lung Cancers on the LIBRETTO-001 Trial (2023)

&lt;p&gt;TEAEs and TRAEs of any grade&lt;/p&gt;
The electrical conductivity and its relationship to the glass transition temperature of plasticized polyacrylonitrile (1976)

Compensation effects present in polyacrylonitrile consisting of solid solutions of hydrated perchlorate salts in a PAN matrix are discussed. A conductivity mechanism is proposed and a relationship between the glass transition temperatures and the activation energies of the conductivity Arrhenius plots for the rubber-like high-temperature region is given.
Effects of symbol time misalignment and frequency offset on performance of realistic all-optical OFDM system (2013)

We theoretically investigate the performance of realistic all-optical orthogonal frequency division multiplexing (AO-OFDM) system and analyzed effects of OFDM symbol time misalignment and frequency offset between transmitter and receiver on performance of AO-OFDM system. For 10-subcarrier system without cyclic prefix (CP), results shows that the time misalignment gives more penalty in received Q <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> and high BER than frequency offset, measured for subcarrier at middle. To keep BER performance under 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-3</sup> for subcarriers at middle, maximum acceptable relative deviation for symbol time misalignment is 16% and for frequency offset is 24%.
Origin of the “ohmic” current in organic field‐effect transistors (1996)

Efforts to improve organic field‐effect transistors (OFETs) have so far concentrated mainly on their field‐effect mobility, but another important parameter is the on–off ratio, i.e., the ratio of the saturation current at maximum absolute gate voltage ( V g ) to that at zero V g . It is shown how an understanding of the so‐called “ohmic” current, which reduces this ratio, will perhaps lead to improved performances now it has been recognized that this current is connected with mobile dopants.
TBB on NUMA Architectures (2019)

Advanced programmers who care about performance know that exploiting locality is paramount. When it comes to locality, cache locality is the one that immediately springs to mind, but in many cases, for heavy-duty applications running on large shared-memory architectures, Non-Uniform Memory Access (NUMA) locality should also be considered. As you certainly know, NUMA conveys the message that memory is organized in different banks and some cores have faster access to some of the “close” banks than to “far” banks. More formally, a NUMA node is a grouping of the cores, caches, and local memory in which all cores share the same access time to the local shared caches and memory. Access time from one NUMA node to a different one can be significantly larger. Some questions arise, such as how the program data structures are allocated on the different NUMA nodes and where the threads that process these data structures are running (are they close or far from the data?). In this chapter, we address these questions, but more importantly, what can be done to exploit NUMA locality within a TBB parallel application.
Spatial Distribution of Immune Cells in Head and Neck Squamous Cell Carcinomas (2021)

Different immune cell distribution patterns within tumors might be crucial for ICI treatment response since hot tumors have the highest expressions of PD-1 and PD-L1. TGF-β might be a key regulator for immune cell distribution and a promising therapeutic target that determines the formation of hot or excluded immune patterns.
A Calibrated, High‐Resolution GOES Satellite Solar Insolation Product for a Climatology of Florida Evapotranspiration1 (2009)

Paech, Simon J., John R. Mecikalski, David M. Sumner, Chandra S. Pathak, Quinlong Wu, Shafiqul Islam, and Taiye Sangoyomi, 2009. A Calibrated, High‐Resolution GOES Satellite Solar Insolation Product for a Climatology of Florida Evapotranspiration. Journal of the American Water Resources Association (JAWRA) 45(6):1328‐1342. Abstract: Estimates of incoming solar radiation (insolation) from Geostationary Operational Environmental Satellite observations have been produced for the state of Florida over a 10‐year period (1995‐2004). These insolation estimates were developed into well‐calibrated half‐hourly and daily integrated solar insolation fields over the state at 2 km resolution, in addition to a 2‐week running minimum surface albedo product. Model results of the daily integrated insolation were compared with ground‐based pyranometers, and as a result, the entire dataset was calibrated. This calibration was accomplished through a three‐step process: (1) comparison with ground‐based pyranometer measurements on clear (noncloudy) reference days, (2) correcting for a bias related to cloudiness, and (3) deriving a monthly bias correction factor. Precalibration results indicated good model performance, with a station‐averaged model error of 2.2 MJ m −2 /day (13%). Calibration reduced errors to 1.7 MJ m −2 /day (10%), and also removed temporal‐related, seasonal‐related, and satellite sensor‐related biases. The calibrated insolation dataset will subsequently be used by state of Florida Water Management Districts to produce statewide, 2‐km resolution maps of estimated daily reference and potential evapotranspiration for water management‐related activities.
Accurate velocity measurements of AFM-cantilever vibrations by Doppler interferometry (2006)

Doppler velocimetry is widely used in the measurement of nanometre resonance vibrations of micro-electromechanical systems (MEMS). It has excellent sensitivity and precision, but typical engineering applications do not require traceability of these velocity measurements to the SI system. While Doppler velocimetry is, in principle, easy to make traceable to the velocity of light, in practice a frequency-to-voltage conversion in common commercial instruments breaks this traceability unless calibrated. Typically, though, calibration is performed at a much lower frequency than those typical of MEMS devices, without the guarantee that the calibration is applicable in this higher frequency regime. We present a method of traceable measurement of velocity in terms of the velocity of light, valid for the range of frequency and nanometre amplitudes typical of MEMS devices driven to resonance vibration. This is achieved by analysis of sideband amplitudes in the interference spectrum before demodulation of the Doppler signal. These sideband amplitudes can conveniently be measured using a benchtop spectrum analyser, a piece of widely available electrical test equipment. We illustrate the method with measurements on individual AFM cantilevers. In combination with cantilever calibration methods based on MEMS devices this method enables traceable calibration of those cantilevers employed for the measurement of pico- and nanonewton forces between individual biomolecules.
Experimental Investigation of Terahertz Wave Scattering by Statistically Controlled Rough Surfaces (2019)

In this work, the experimental investigation of electromagnetic wave scattering by statistically controlled rough surfaces in the lower THz band is demonstrated. Rough surfaces with height fluctuations following normal statistics are fabricated using two different 3D printing techniques. The results presented here confirm that the surface roughness has a noticeable effect on the level of the diffuse scattering energy. In the future, the applied method can be used to validate analytical models as well as to gain scattering patterns from more complicated rough surface structures which fall outside the limits of most analytical approximations.
NONLINEAR MODEL PREDICTIVE CONTROL (1990)

Abstract Nonlinear Model Predictive Control (NMPC), a strategy for constrained, feedback control of nonlinear processes, has been developed. The algorithm uses a simultaneous solution and optimization approach to determine the open-loop optimal manipulated variable trajectory at each sampling instant. Feedback is incorporated via an estimator, which uses process measurements to infer unmeasured state and disturbance values. These are used by the controller to determine the future optimal control policy. This scheme can be used to control processes described by different kinds of models, such as nonlinear ordinary differential/algebraic equations, partial differential/algebraic equations, integra-differential equations and delay equations. The advantages of the proposed NMPC scheme are demonstrated with the start-up of a non-isothermal, non-adiabatic CSTR with an irreversible, first-order reaction. The set-point corresponds to an open-loop unstable steady state. Comparisons have been made with controllers designed using (1) nonlinear variable transformations, (2) a linear controller tuned using the internal model control approach, and (3) open-loop optimal control. NMPC was able to bring the controlled variable to its set-point quickly and smoothly from a wide variety of initial conditions. Unlike the other controllers, NMPC dealt with constraints in an explicit manner without any degradation in the quality of control. NMPC also demonstrated superior performance in the presence of a moderate amount of error in the model parameters, and the process was brought to its set-point without steady-state offset.
Combining Displacement Field and Grip Force Information to Determine Mechanical Properties of Planar Tissue With Complicated Geometry (2014)

Performing planar biaxial testing and using nominal stress-strain curves for soft-tissue characterization is most suitable when (1) the test produces homogeneous strain fields, (2) fibers are aligned with the coordinate axes, and (3) strains are measured far from boundaries. Some tissue types [such as lamellae of the annulus fibrosus (AF)] may not allow for these conditions to be met due to their natural geometry and constitution. The objective of this work was to develop and test a method utilizing a surface displacement field, grip force-stretch data, and finite-element (FE) modeling to facilitate analysis of such complex samples. We evaluated the method by regressing a simple structural model to simulated and experimental data. Three different tissues with different characteristics were used: Superficial pectoralis major (SPM) (anisotropic, aligned with axes), facet capsular ligament (FCL) (anisotropic, aligned with axes, bone attached), and a lamella from the AF (anisotropic, aligned off-axis, bone attached). We found that the surface displacement field or the grip force-stretch data information alone is insufficient to determine a unique parameter set. Utilizing both data types provided tight confidence regions (CRs) of the regressed parameters and low parameter sensitivity to initial guess. This combined fitting approach provided robust characterization of tissues with varying fiber orientations and boundaries and is applicable to tissues that are poorly suited to standard biaxial testing. The structural model, a set of C++ finite-element routines, and a Matlab routine to do the fitting based on a set of force/displacement data is provided in the on-line supplementary material.
Preventative effects of a probiotic, Lactobacillus salivarius ssp. salivarius, in the TNBS model of rat colitis. (2005)

Administration of the probiotic L. salivarius ssp. salivarius CECT5713 facilitates the recovery of the inflamed tissue in the TNBS model of rat colitis, an effect associated with amelioration of the production of some of the mediators involved in the inflammatory response in the intestine, such as cytokines, including TNF-alpha and NO. This beneficial effect could be ascribed to its effect on the altered immune response that occurs in this inflammatory condition.
Online Monitoring of Airborne Allergenic Particles (OMNIBUSS) (2006)

S.31-87
Detection of SV40 DNA sequences in malignant mesothelioma specimens from the United States, but not from Turkey (2002)

The incidence of malignant mesothelioma (MM) shows a strong epidemiological association with exposure to asbestos fibers. Recently, simian virus 40 (SV40) DNA sequences have been reported in MM tumor specimens from the United States and several European countries, and the SV40 tumor virus has been implicated as a potential co-factor in the etiology of this disease. However, several large studies from the US, Finland, and Turkey did not detect SV40 sequences in MM samples. To address this discrepancy, MM specimens from Turkey and the US were analyzed in the same laboratory under identical conditions to detect the presence of SV40 DNA. We detected SV40 sequences in 4 of 11 specimens from the United States, but in none of the 9 Turkish samples examined. These findings suggest that geographical differences exist with regard to the involvement of SV40 in human tumors.
Optical transitions and Rabi oscillations in waveguide arrays (2008)

It is theoretically demonstrated that Rabi interband oscillations are possible in waveguide arrays. Such transitions can take place in optical lattices when the unit-cell is periodically modulated along the propagation direction. Under phase-matching conditions, direct power transfer between two Floquet-Bloch modes can occur. In the nonlinear domain, periodic oscillations between two different lattice solitons are also possible.
Adsorption of Plasmid DNA onto N,N‘- (Dimethylamino)ethyl-methacrylate Graft-Polymerized Poly-l-lactic Acid Film Surface for Promotion of in-Situ Gene Delivery (2007)

The surface of biodegradable poly-L-lactic acid (PLLA) film was modified with N,N'-(dimethylamino)ethyl-methacrylate (DMAEMA) via UV-induced graft copolymerization, and plasmid DNA molecules were adsorbed onto the surface of modified PLLA film by electrostatic interactions with cationic DMAEMA polymer. We characterized the structure of the modified PLLA film surface by Fourier transform infrared attenuated total reflection (FTIR-ATR) spectroscopy and X-ray photoelectron spectroscopy (XPS). The weight-average molecular weight (Mw) of grafted DMAEMA polymer chains was estimated from the elution time of gel filtration chromatography. C.I. Acid Orange 7 dyeing results indicated that graft density of DMAEMA on PLLA film increased with the UV irradiation time and then reached a saturated value. DNA adsorption density was proportioned to graft density of DMAEMA. Mouse fibroblast L929 cell line was cultured on modified PLLA films, and cell viability and gene transfection efficiency were monitored after 2 days culture. It was found that the DMAEMA grafted PLLA film had obvious cytotoxicity to the cells. On the contrary, cytotoxicity of the surface was highly decreased after adsorption with plasmid DNA. This DNA adsorbed DMAEMA modified PLLA showed the ability to deliver DNA into mammalian cells cultured on the surface with high-transfection efficiency at a low DNA amount. The present results suggest that the DMAEMA grafted PLLA has potentiality to be used as a safe and effective gene delivery system in gene-activated materials.
Role of the NiFe Hydrogenase Hya in Oxidative Stress Defense in Geobacter sulfurreducens (2012)

Geobacter sulfurreducens, an Fe(III)-reducing deltaproteobacterium found in anoxic subsurface environments, contains 4 NiFe hydrogenases. Hyb, a periplasmically oriented membrane-bound NiFe hydrogenase, is essential for hydrogen-dependent growth. The functions of the three other hydrogenases are unknown. We show here that the other periplasmically oriented membrane-bound NiFe hydrogenase, Hya, is necessary for growth after exposure to oxidative stress when hydrogen or a highly limiting concentration of acetate is the electron source. The beneficial impact of Hya on growth was dependent on the presence of H(2) in the atmosphere. Moreover, the Hya-deficient strain was more sensitive to the presence of superoxide or hydrogen peroxide. Hya was also required to safeguard Hyb hydrogen oxidation activity after exposure to O(2). Overexpression studies demonstrated that Hya was more resistant to oxidative stress than Hyb. Overexpression of Hya also resulted in the creation of a recombinant strain better fitted for exposure to oxidative stress than wild-type G. sulfurreducens. These results demonstrate that one of the physiological roles of the O(2)-resistant Hya is to participate in the oxidative stress defense of G. sulfurreducens.