gebhart/patrepeval huggingface dataset:
Predicting football injuries using size and ratio of the multifidus and quadratus lumborum muscles (2016)

Deficits in muscles of the lumbo-pelvic region, such as a relatively small multifidus muscle, have been used to predict lower limb injuries in professional football players. Results have been less consistent for the size of the quadratus lumborum (QL) muscle. Changes in size of the multifidus and QL muscles could be functionally related to each other, and modeling this relationship could improve prediction of lower limb injuries. Ultrasound imaging examinations were performed on male elite football players at the start of the Australian Football League (AFL) pre-season and playing season. Injury data were obtained from records collected by each club. Results indicated that the cross-sectional area of the multifidus muscle was related to the occurrence of an injury in the pre-season (odds ratio [OR] = 2.08/cm<sup>2</sup> decrease below the mean; OR for dichotomized measure = 12.2) and in the season (OR = 2.43/cm<sup>2</sup> ). The size of the QL muscle was significantly related to an injury in the pre-season (OR = 2.12/cm<sup>2</sup> increase above the mean; OR for dichotomized measure = 7.26) but not in the season. A significant link was found between the ratio of the multifidus and QL muscles, and the incidence of pre-season (OR = 14.71) and season injuries (OR = 5.29). The sensitivity and specificity of the model in the pre-season were 75% and 85.7%, respectively; values for the playing season were 88.4% and 62.5%. A model was developed for prediction of lower limb injuries in football players. Combining size measurements of the multifidus and QL muscles improved predictive power. This information may have clinical implications for injury screening and prevention.
Diagnostic Utility of Smartwatch Technology for Atrial Fibrillation Detection – A Systematic Analysis (2020)

Smartwatch based single-lead ECG and photoplethysmography appear to be reasonable alternatives for AF monitoring.
Design of Autonomic SLA Manager for Service Applications (2007)

Internet-based businesses become more profitable, and their business scopes are extended, mainly due to new effective IT paradigms characterized by service- oriented computing and autonomic computing. The technologies offered by these paradigms provide a new way of managing e-Business services and infrastructures with minimum human intervention, i.e. autonomous fashion. However, the dynamic nature of service-oriented architecture (SOA) makes such autonomic management harder. More specifically, defining events, monitoring services, and analyzing anomalistic behavior are quite cumbersome. Autonomic SIA Manager is a cost-effective and robust solution to the problems. In this paper, we present the architecture of Autonomic SIA Manager (ASM), its main components, such as policy decision-making language, interface wrapper, autonomic service event handler. We also conduct a case study to show how ASM manages the SIA effectively.
Differential Transcriptional Expression Profiles of Juvenile and Adult Calvarial Bone (2005)

These findings reflect a genomic environment of active osteoblast differentiation and ossification in the juvenile calvaria compared with the adult "quiescent" calvarial tissue. These data suggest that a decreased osteogenic potential of adult calvarial osteoblasts may, in part, explain the inability of adult animals to heal calvarial defects.
Propionibacterium Endophthalmitis Following Molteno Tube Repositioning (1997)

Tube reinsertion into the anterior chamber resulted in recurrence of the infection. The evaluation of alternative therapies of aqueous tube shunt-related endophthalmitis would require a large case-controlled series of patients.
Supplementary Figure 2 from Altered Runx1 Subnuclear Targeting Enhances Myeloid Cell Proliferation and Blocks Differentiation by Activating a miR-24/MKP-7/MAPK Network (2023)

Supplementary Figure 2 from Altered Runx1 Subnuclear Targeting Enhances Myeloid Cell Proliferation and Blocks Differentiation by Activating a miR-24/MKP-7/MAPK Network
Single-mode operation of coupled-cavity GaInAsP/InP semiconductor lasers (1983)

Monolithic two-section GaInAsP/InP lasers are shown to operate in a single longitudinal mode under high-speed pulsed current modulation. The length of the emitted monomode light pulses is less than 500 ps. The suppression of secondary modes is described in a rate equation model that is generally useful for a variety of coupled-cavity configurations. It is found that 10% increase in cavity loss for the unwanted modes is sufficient to provide 17 dB suppression.
Barriers to healthcare utilization in fatiguing illness: a population-based study in Georgia (2009)

Barriers to healthcare utilization pose a significant problem in persons with fatiguing illnesses. Study results suggested two-fold implications: a symptom-targeted model focusing on symptoms associated with fatigue; and an interactive model requiring efforts from patients and providers to improve interactions between them by reducing barriers in accessibility, KABs, and healthcare system.
The health and social implications of household air pollution and respiratory diseases (2019)

Approximately three billion individuals are exposed to household air pollution (HAP) from the burning of biomass fuels worldwide. Household air pollution is responsible for 2.9 million annual deaths and causes significant health, economic and social consequences, particularly in low- and middle-income countries. Although there is biological plausibility to draw an association between HAP exposure and respiratory diseases, existing evidence is either lacking or conflicting. We abstracted systematic reviews and meta-analyses for summaries available for common respiratory diseases in any age group and performed a literature search to complement these reviews with newly published studies. Based on the literature summarized in this review, HAP exposure has been associated with acute respiratory infections, tuberculosis, asthma, chronic obstructive pulmonary disease, pneumoconiosis, head and neck cancers, and lung cancer. No study, however, has established a causal link between HAP exposure and respiratory disease. Furthermore, few studies have controlled for tobacco smoke exposure and outdoor air pollution. More studies with consistent diagnostic criteria and exposure monitoring are needed to accurately document the association between household air pollution exposure and respiratory disease. Better environmental exposure monitoring is critical to better separate the contributions of household air pollution from that of other exposures, including ambient air pollution and tobacco smoking. Clinicians should be aware that patients with current or past HAP exposure are at increased risk for respiratory diseases or malignancies and may want to consider earlier screening in this population.
Self-reported burden of lung cancer for patients who experienced considerable weight loss vs. those who did not. (2016)

e21608 Background: The objective of this study was to compare the self-reported disease burden and experiences of patients with advanced non-small cell lung cancer (NSCLC) who reported considerable weight loss ( ≥ 5% of their body weight in the past 6 months or ≥ 2% for a BMI less than 20 kg/m2) to those who did not. Methods: 95 members of PatientsLikeMe patients community (age mean = 59; 81% females; 81% US residents) with self-reported diagnosis of advanced NSCLC completed an online survey that assessed health-related quality of life (QLQ-C15-PAL), ECOG Performance Status, anorexia-cachexia symptoms/concerns (FAACT A/CS domain), distress levels, clinical/demographic characteristics (including height and past and current weight), and impact of weight loss (open-ended questions). Results from patients with and without weight loss were compared using chi-squared test, a t-test or a Kruskal-Wallis test, as appropriate. Results: 35 (36.3%) patients were classified as having considerable weight loss at the time of the survey and 60 (63.2%) were classified without. 48 (51%) patients self-rated their ECOG Performance Status as 1, and 58 (61%) patients indicated not receiving either chemotherapy or radiotherapy at the time of the survey. Patients with weight loss reported significantly (p < 0.05) lower overall quality of life (55.2 vs. 66.9), worsened anorexia-cachexia symptoms/concerns (30.7 vs. 36.0), and higher symptomology, specifically fatigue (64.8 vs. 49.1), nausea (19.5 vs. 9.2), and appetite loss (41.0 vs. 23.9) – than patients without weight loss. In addition, significantly more patients who lost weight reported moderate/high distress levels than patients who did not (71% vs. 38%). Main worries for patients with weight loss included loss of energy and disease progression. Conclusions: Our results support that weight loss represents a substantial problem for NSCLC patients, associated with lower quality of life, higher distress level and more severe symptoms, particularly in terms of fatigue, nausea, and appetite loss. Interventions targeted at maintaining/increasing body weight may help to improve well-being and reduce key symptoms in advanced NSCLC patients with considerable weight loss.
Changes in sensory functions after low-frequency repetitive transcranial magnetic stimulation over the motor cortex. (2009)

Low-frequency rTMS over the M1 provides global anesthetic effects and inhibits excitability in S1. The lack of correlation between these changes suggests that the anesthetic effects may not always relate to the excitability of S1; thus, the mechanisms responsible for the changes remain unclear. Nevertheless, these findings suggest that rTMS may be a useful strategy for treating intractable pain in rehabilitation medicine.
A SiGe D-Band x12 Frequency Multiplier with Gilbert Cell-Based Tripler (2022)

The design and measurement results of a fully-integrated x12 frequency multiplier for D-Band applications in Infineon’s 0.13 µm SiGe BiCMOS technology B11HFC are presented. The frequency multiplier consists of active baluns, frequency doublers, distribution networks, amplifiers, and Gilbert cells. To generate a D-Band signal, the frequency of an input signal is first doubled twice and then tripled. The approach used to triple the frequency is to utilize Gilbert cells instead of a push-pull tripler. Overall, the x12 frequency multiplier exhibits a measured 3 dB bandwidth of 37.5 GHz at a center frequency of 136.25 GHz. The variation of the output power is smaller than 9 dB in the entire D-Band. In addition, the measured harmonic rejection is approximately 24.5 dB at the center frequency.
[Laparoscopic surgery for advanced colorectal cancer]. (2004)

Laparoscopic colectomy for benign diseases and early cancers has been widely accepted since the first report on it was published in 1991. The indications for laparoscopic colectomy have been expanded with advances in the operative technique and instrumentation. Although laparoscopic surgery for advanced colorectal cancer is technically feasible, the long-term outcome should be confirmed in prospective, randomized, controlled trials of laparoscopic surgery in the treatment of advanced colorectal cancer.
Thermal and thermomechanical properties of biocomposites made from modified recycled cellulose and recycled polypropylene (2003)

Abstract Residual cellulose fibers from the paper industry have been used as reinforcements in recycled polypropylene (PP) composites. The main obstacle to obtaining good properties with this biocomposite is deficiencies in the compatibility between the nonpolar matrices and the polar cellulose fibers used as reinforcements. The aim of this work was to improve the compatibilization between these cellulose fibers and the PP matrix with four different methods: modification by the addition of polypropylene–maleic anhydride copolymer (PPgMA) during the process of blending, preblending modification of the cellulose with a solution of PPgMA, modification of cellulose by silanes (vinyltrimethoxysilane), and acetylation of cellulose. Blends with all of the differently modified celluloses were prepared with the cellulose content varied up to 40%, and then all of the blends were subjected to thermal (differential scanning calorimetry and thermogravimetric analysis) and thermomechanical (dynamic mechanical thermal analysis) analyses. The results showed that the addition of cellulose fibers improved the thermomechanical behavior of the PP, increasing the value of the log of the dynamic modulus, and affected the thermal and thermooxidative behavior. Moreover, an advantage of the use of a recycled PP containing a small quantity of ethyl vinyl acetate (EVA) as a prime material in the composition was the enhancement of mechanical properties. The use of these methods for the modification of cellulose led to more desirable thermal and thermooxidative stabilities. © 2003 Wiley Periodicals, Inc. J Appl Polym Sci 89: 2353–2360, 2003
Sclerotic atrophic plaques associated with a tattoo (2014)

Lichen sclerosus is a chronic inflammatory disease, usually of the anogenital area, that causes intractable itching and soreness. Less commonly, it may have extragenital involvement in 15 to 20% of cases. Lichen sclerosus has been reported at sites of injury as a Koebner phenomenon. We report a case of lichen sclerosus at the site of a tattoo with simultaneous genital involvement.
Surface temperature of decomposing construction materials studied by laser‐induced phosphorescence (2004)

Abstract Measurements of surface temperature and mass loss of decomposing construction materials during rapid pyrolysis are presented. Experiments have been performed with samples of low‐density fiberboard, medium‐density fiberboard, particleboard and poly(methyl methacrylate) in a single particle reactor at temperatures between 300° and 600°C. Ultraviolet laser light was used to excite micrometer‐sized thermographic phosphor particles that were deposited on the investigated materials, and the temperature was obtained from temporally resolved measurements of the laser‐induced emission. The wood‐based materials show a similar behavior, with small differences being attributed to differences in material properties. The surface temperature rapidly increases to about 400°C when a particle is introduced to the hot reactor. The initial phase is followed by rapid decomposition during which the surface temperature is 380°–540°C. The heating rate is slowed down during the rapid pyrolysis, and again increases as the remaining char is heated to the reactor temperature. The poly (methyl methacrylate), however, melts and at high temperatures can be characterized as a liquid with a boiling point of about 400°C. Thermographic phosphors are concluded to be suitable for high precision remote measurements of the surface temperature of decomposing construction materials, and possibilities for further studies and developments of the technique are discussed. Copyright © 2004 John Wiley &amp; Sons, Ltd.
Dynamic Modeling from Flight Data with Unknown Time Skews (2016)

A method for estimating dynamic model parameters from flight data with unknown time skews is described and demonstrated. The method combines data reconstruction, nonlinear optimization, and equation-error parameter estimation in the frequency domain to accurately estimate both dynamic model parameters and the relative time skews in the data. Data from a nonlinear F-16 aircraft simulation with realistic noise, instrumentation errors, and arbitrary time skews were used to demonstrate the approach. The approach was further evaluated using flight data from a subscale jet transport aircraft, where the measured data were known to have relative time skews. Comparison of modeling results obtained from time-skewed and time-synchronized data showed that the method accurately estimates both dynamic model parameters and relative time skew parameters from flight data with unknown time skews.
Controlled formation of allenes with organocuprates (1976)

P. Crabbé, E. Barreiro, J. Dollat and J. Luche, J. Chem. Soc., Chem. Commun., 1976, 183 DOI: 10.1039/C39760000183
Regulation of Polar Peptidoglycan Biosynthesis by Wag31 Phosphorylation in Mycobacteria (2010)

The Wag31Mtb phosphorylation is a novel molecular mechanism by which Wag31Mtb regulates peptidoglycan synthesis and thus, optimal growth in mycobacteria.
Candidate .gamma.-Secretases in the Generation of the Carboxyl Terminus of the Alzheimer's Disease .beta.A4 Amyloid: Possible Involvement of Cathepsin D (1995)

beta A4 amyloid peptide, the main constituent of amyloid plaques and cerebrovascular amyloid deposits associated with Alzheimer's disease, derives from a large precursor protein (APP) by the action of beta- and gamma-secretases, the unidentified endoproteases which release the amino and carboxyl termini of beta A4, respectively. Several gamma-secretase cleavage sites exist which yield the more soluble (1-39/40) forms of beta A4 and the longer forms (1-42/43) which have a greater tendency to aggregate into amyloid plaques. gamma-Secretase activity may therefore be critical in amyloid formation. In this study, a synthetic peptide which encompasses the various gamma-secretase cleavage sites was used as a substrate to probe proteases of various classes and specificities. Elastase, collagenase, and cathepsin D cleaved at the amyloidogenic sites (after Ala42 or after Thr43) to release the carboxyl termini of the aggregating forms. In addition, collagenase and pepsin released the carboxyl terminus of the more soluble forms. Human brain fractions enriched in lysosomes contained a proteolytic activity that cleaved the substrate at the amyloidogenic site(s). This activity was more active at acidic pH and was inhibited by pepstatin, two characteristics of the lysosomal aspartyl proteinase cathepsin D. The same lysosomal fractions were found to contain APP carboxyl-terminal fragments which are potentially amyloidogenic. These were degraded, only in acidic conditions, by an endogenous protease activity inhibited by pepstatin. Thus, a cathepsin D-like activity from human brain is a candidate for APP gamma-secretase(s).
Presence of high concentrations of circulating Toxoplasma antigens during acute Toxoplasma infection in athymic nude mice (1987)

In mice infected with an avirulent strain of Toxoplasma gondii, circulating Toxoplasma antigens were detectable in the sera during weeks 1 to 3 of infection by a simple agglutination test that uses latex particles coated with anti-Toxoplasma antibodies. An infection in athymic nude mice resulted in high agglutination titers in the anti-Toxoplasma antibody-coated latex particle test and the absence of anti-Toxoplasma antibodies in sera during the acute phase, suggesting that the detection of circulating Toxoplasma antigens is a good tool for the diagnosis of acute toxoplasmosis, especially in severely immunocompromised hosts.
Vancomycin‐resistant Enterococcus faecium infection in patients with hematologic malignancy: patients with acute myeloid leukemia are at high‐risk (2007)

Risk stratification for development of VRE infection is possible for patients with hematologic malignancy. Patients with AML represent a high-risk population, and targeted prevention strategies must include improved antibiotic stewardship, particularly judicious use of vancomycin therapy.
Some pharmacological properties of a newly synthesized morphine derivative, (-)-6 beta-acetylthiomorphine. (1989)

Some pharmacological properties of a newly synthesized morphine derivative, (-)-6 beta-acetylthiomorphine (AcS-morphine) were studied. AcS-morphine was about twice as potent as morphine in the inhibitory action of the twitch response of the guinea-pig ileal preparation to electrical stimulation. AcS-morphine, however, was 5 times as potent as morphine in the analgesic action in the rats. Both the effects of AcS-morphine were inhibited by naloxone, suggesting that the site of action of AcS-morphine is mu-receptors. It is interesting that 6 beta-isomer of AcS-morphine is 5 times as potent as 6 alpha-OH isomer of morphine in the analgesic action, because 6 alpha-OH isomer of morphine is much more potent than that of 6 beta-OH isomer. The effects of AcS-morphine on the specific binding of [3H]-naloxone, [3H]-ethylketocyclazocine and [3H]-D-Ala2-D-Leu5-enkephalin to the membrane fractions from the rat brain were tested. AcS-morphine was about 5 times as potent as morphine in its interactions with opioid receptors, as determined by the binding assay. AcS-morphine, as well as morphine, had a selectively high affinity to mu-receptors. The "sodium effect" and the "GTP effect" of AcS-morphine were almost the same as those of morphine. The dependence liability of AcS-morphine was preliminary tested in the guinea-pig ileal preparations treated with a high concentration of AcS-morphine for 24 hr. Results suggested that AcS-morphine is weaker than morphine in its dependence liability, though it seems almost certain that AcS-morphine does have this liability.
Modeling normal brain asymmetry in MR images applied to anomaly detection without segmentation and data annotation (2019)

While the human brain presents natural structural asymmetries between left and right hemispheres in MR images, most neurological diseases are associated with abnormal brain asymmetries. Due to the great variety of such anomalies, we present a framework to model normal structural brain asymmetry from control subjects only, independent of the neurological disease. The model dismisses data annotation by exploiting generative deep neural networks and one-class classifiers. We also propose a patch-based model to localize volumes of interest with reduced background sizes around selected brain structures and a one-class classifier based on an optimum-path forest. This model makes the framework independent of segmentation, which may fail, especially in abnormal images, or may not be available for a given structure. We validate the first method to the detection of abnormal hippocampal asymmetry using distinct groups of Epilepsy patients and testing controls. The results of validation using the original feature space and a two-dimensional space based on non-linear projection show the potential to extend the framework for abnormal asymmetry detection in other parts of the brain and develop intelligent and interactive virtual environments. For instance, the approach can be used for screening, inspection, and annotation of the detected anomaly type, allowing the development of CADx systems.
513 Cutting characteristic of a unique double structure cutter in relation with applied loads (2006)

During paperboard cutting, unbalancc of cutters cutttng point could causc in a short cutter life. In order to solve this p;oblem, a cutter with a cutting tip and a soft bottom tip was designed, namely a "doubte structure cutter" (Fig. The cutting tip hardness region is abeut O.3mm from its tip with a hardness of 700HV wherc the bottom tip hardness is 340HV and the yielding stress 6y is 582MPa. (Fig. Tlic cutter outer layer is decarburized and will result in the increasing of its malleability. Initial thickness wt, wb for the cutting tip and the bottem tip is about 4pan and 150ym respectively. The main approach of this cutter is the soft bottom edges will compresses in order to match the uneven cuuing points. H. Kondo et al. has analyzed the hardened tip deformation transformation process on a norrnal cutter under various loads [1], Howeveg there were no studies eonducted on a cutter with two tips. This paper discussed a deformation characteristic of a double structure ctmer in a static compression mode and in relation with various line forces ranging from 50kNlm to 350kN/m. For comparison, the same experiment was also conducted to a norrnal cutter with one side cuuing edge and a flat bottom edge, but haS the sarne material properties as the double structure cutter.