gebhart/patrepeval huggingface dataset:
Determination of adhesion between thermoplastic and liquid silicone rubbers in hard-soft-combinations via mechanical peeling test (2014)

The production of hard-soft-combinations via multi injection molding gained more and more importance in the last years. This is attributed to different factors. One principle reason is that the use of two-component injection molding technique has many advantages such as cancelling subsequent and complex steps and shortening the process chain. Furthermore this technique allows the combination of the properties of the single components like the high stiffness of the hard component and the elastic properties of the soft component. Because of the incompatibility of some polymers the adhesion on the interface has to be determined. Thereby adhesion is not only influenced by the applied polymers, but also by the injection molding parameters and the characteristics of the mold. Besides already known combinations of thermoplastics with thermoplastic elastomers (TPE), there consists the possibility to apply liquid silicone rubber (LSR) as soft component. A thermoplastic/LSR combination gains in importance due to the specific advantages of LSR to TPE. The faintly adhesion between LSR and thermoplastics is currently one of the key challenges when dealing with those combinations. So it is coercively necessary to improve adhesion between the two components by adding an adhesion promoter. To determine the promoters influence, it is necessary to develop a suitable testing method to investigate e.g. the peel resistance. The current German standard "VDI Richtlinie 2019', which is actually only employed for thermoplastic/TPE combinations, can serve as a model to determine the adhesion of thermoplastic/LSR combinations.
A new motion-compensated reduced-order model Kalman filter for space-varying restoration of progressive and interlaced video (1998)

We propose a new approach for motion-compensated, reduced order model Kalman filtering for restoration of progressive and interlaced video. In the case of interlaced inputs, the proposed filter also performs deinterlacing. In contrast to the literature, both motion-compensation and reduced-order state modeling are achieved by augmenting the observation equation, as opposed to modifying the state-transition equation. The proposed modeling, which includes the two-dimensional (2-D) reduced order model Kalman filtering (ROMKF) of Angwin and Kaufman as a special case, results in significant performance improvement in fixed-lag Kalman filtering of space-varying blurred images. This is demonstrated by experimental results.
Control strategy design for a turbocharged SI engine (2007)

This paper deals with the nonlinear modeling and control of a turbocharged spark ignition (SI) engine. In automotive industry, downsizing based turbocharging is considered as a powerful technique to improve engine performances such as fuel economy and pumping loss reduction to increase engine efficiency or to optimize the drivability. This method is widely used for diesel engine. For gasoline engines, it is more complex in terms of control. In this work, a simplified control oriented model is presented. Then, to achieve the control objectives, a decentralized control strategy based on linear and nonlinear fuzzy controllers is developed and experimentally applied on a Smart MCC (Micro Compact Car) three cylinders engine test bench.
Formation and characterization of .eta.2-imine and .eta.2-azobenzene derivatives of titanium containing ancillary aryloxide ligation (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFormation and characterization of .eta.2-imine and .eta.2-azobenzene derivatives of titanium containing ancillary aryloxide ligationLoren D. Durfee, John E. Hill, Phillip E. Fanwick, and Ian P. RothwellCite this: Organometallics 1990, 9, 1, 75–80Publication Date (Print):January 1, 1990Publication History Published online1 May 2002Published inissue 1 January 1990https://pubs.acs.org/doi/10.1021/om00115a012https://doi.org/10.1021/om00115a012research-articleACS PublicationsRequest reuse permissionsArticle Views380Altmetric-Citations83LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
An Image Analysis Method for Cell-Size and Cell-Size Distribution Measurement in Rigid Foams (1996)

The basic morphological unit of a closed cell rigid foam is the gas-filled cavity surrounded by cell walls and struts. Typically, these cavities (cells) are pentagonal dodecahedral or tetrakaidecahedral. Their average dimensions and dispersity are known to influence foam physical properties and foam performance. We have devised a reliable method for the measurement of cell-size and cell-size distribution which exploits both geometry and statistics, and which has allowed the realization of useful correlations and trends in our development of rigid foam formulations and additives. A thin slice of foam (100-300 microns) is subjected to optical microscopy and image analysis. Measurements of the areas of cell windows and of the average ferets of these windows are made independently. Windows are usually pentagonal, hexagonal or square and are variously distorted. Cells are assumed to be dodecahedral and cell diameter ( d ) is calculated by the formulae: d = 2.1354 (area) 1/2 d = 1.7013 (feret) Thereby, two independent determinations of cell diameter are obtained from each window viewed. Values are typically within 2% of each other. Cell-size distribution is quantified by measuring a large number (~ 500-1000) of windows and calculating the simple and weighted averages. This paper will present the mathematical basis for the method, illustrate the excellent agreement between the window area and the feret cell-size determinations and demonstrate the utility of cell-size and cell-size distribution data in physical property correlations, for example for k -factor.
Meropenem: A New Carbapenem Antimicrobial (1994)

Meropenem is comparable to imipenem in terms of in vitro susceptibility pattern and pharmacokinetic disposition. Overall, meropenem seems to offer promise as the second of the carbapenem class of antibiotics. Clinical data are preliminary, and further data are needed.
Fault Tolerance for VLSI Multicomputers (1985)

The performance requirements of future high-end computers will only be met by systems that facilitate the exploitation of the parallelism inherent in the algorithms that they execute. One such system is a multicomputer that consists of hundreds or thousands of VLSI computation nodes interconnected by dedicated links. Some important applications of high-end computers, such as weather forecasting, require continuous correct operation for many hours. This requirement can only be met if the system is fault-tolerant, i.e., can continue to operate correctly despite the failure of some of its components. This dissertation investigates the use of fault tolerance techniques to increase the reliability of VLSI multicomputers. Different techniques are evaluated in the context of the entire system, its implementation technology, and intended applications. A proposed fault tolerance scheme combines hardware that performs error detection and system-level protocols for error recovery and fault treatment. Practical design and implementation tradeoffs are discussed. &lt;p&gt; A fault-tolerant system must identify erroneous information produced by faulty hardware. It is shown that a high probability of error detection can be achieved with self-checking nodes implemented using duplication and comparison. The requirements for detecting errors caused by hardware faults are: (1) the comparator is fault-free, and (2) the functional modules never produce identical incorrect outputs. Requirement (1) is fulfilled with a self-testing comparator that signals its own faults during normal operation. An implementation of such a comparator using MOS PLAs is discussed. Requirement (2) is fulfilled with two modules that are implemented differently so that, although they perform identical functions, they have a low probability of failing simultaneously in exactly the same way. Low-cost techniques for implementing such modules are presented. &lt;p&gt; The detection of an error implies that the state of the system has been corrupted. In order to recover from the error and resume correct operation, a valid system state must be restored. A low-overhead, application-transparent error recovery scheme for multicomputers is presented. It involves periodic checkpointing of the entire system state, using protocols that ensure that the saved states of all the nodes are consistent, and rolling back to the last checkpoint when an error is detected
Capillary electrophoresis of nucleobases and nucleosides detected by TOF/MS (2003)

The TOF/MS detection of nucleobases and nucleosides in capillary electrophoresis using a silica capillary combined with a stainless-steel electrospray ionization interface was studied under acidic conditions. The results showed that the nucleobases were migrated and detected as protonated species, while the nucleosides were detected by TOF/MS as the original nucleosides and the nucleobases fragment formed by collision-induced dissociation, after the migration of nucleosides as protonated species.
Semantics of exact real arithmetic (2002)

In this paper, we incorporate a representation of the non-negative extended real numbers based on the composition of linear fractional transformations with non-negative integer coefficients into the Programming Language for Computable Functions (PCF) with products. We present two models for the extended language and show that they are computationally adequate with respect to the operational semantics.
NO overproduction by eNOS precedes hyperdynamic splanchnic circulation in portal hypertensive rats (1999)

Chronic high blood flow and the hyperdynamic circulatory syndrome in portal hypertension are associated with endothelial constitutive nitric oxide (NO) synthase (eNOS) upregulation and increased NO release. In portal vein-ligated (PVL) rats the splanchnic circulation is not yet hyperdynamic on day 3 postoperatively. In vitro perfused superior mesenteric arteries (SMAs) of day 3 PVL and sham rats were challenged with increasing flow rates or the alpha-adrenoreceptor agonist methoxamine (30 and 100 microM) before and after incubation with the NO inhibitor, Nomega-nitro-L-arginine (L-NNA, 10(-4) M). Perfusate NO metabolite (NOx) concentrations were measured by chemiluminescence. PVL rats expressed a significant hyporesponsiveness to increases in flow rate or methoxamine that was overcome by incubation with L-NNA. The PVL vasculature showed significantly higher slopes of NOx production vs. flow-induced shear stress, higher increases in perfusate NOx concentration in response to methoxamine, and higher eNOS protein levels (Western blot) compared with sham rats. In conclusion, eNOS-upregulation and increased NO release by the SMA endothelium occur before the development of the hyperdynamic splanchnic circulation, suggesting a primary role of NO in the pathogenesis of arterial vasodilatation.
Conductive mixed-order generalized dispersion model for noble metals in the optical regime (2021)

Various dispersion models can be expressed as special cases of the Generalized Dispersion Model (GDM), which is composed of a series of Padé polynomials. While important for its broad applicability, we found that some materials with Drude dispersive terms can be accurately modeled by mixing a 1<sup>st</sup> order Padé polynomial with an extra conductivity term. This conductivity term can be separated from the auxiliary differential equation (ADE). Therefore, the proposed mixed-order model can achieve the same accuracy with fewer unknowns, thus realizing higher computational efficiency and lower memory consumption. For examples, we derive the model parameters and corresponding numerical errors for noble metals including Au, Ag, and Al in the optical regime. Finally, the proposed model's efficiency improvements are validated through implementation within a Discontinuous Galerkin Time Domain (DGTD) framework. The proposed model can achieve up to 12.5% efficiency improvement in theory compared to the conventional GDM with the same accuracy. A numerical example validates that, in practice, 9% memory reduction and 11% acceleration can be realized.
Group IV clathrates: synthesis, optoelectonic properties, and photovoltaic applications (2014)

Group IV clathrates are a unique class of guest/framework type compounds that are considered potential candidates for a wide range of applications (superconductors to semiconductors). To date, most of the research on group IV clathrates has focused heavily on thermoelectric applications. Recently, these materials have attracted attention as a result of their direct, wide band gaps for possible use in photovoltaic applications. Additionally, framework alloying has been shown to result in tunable band gaps. In this review, we discuss the current work and future opportunities concerning the synthesis and optical characterization of group IV clathrates for optoelectronics applications.
Building a scalable and accurate copy detection mechanism (1996)

Often, publishers are reluctant to offer valuable digital documents on the Internet for fear that they will be re-transmitted or copied widely. A Copy Detection Mechanism can help identify such copying. For example, publishers may register their documents with a copy detection server, and the server can then automatically check public sources such as UseNet articles and Web sites for potential illegal copies. The server can search for exact copies, and also for cases where significant portions of documents have been copied. In this paper we study, for the first time, the performance of various copy detection mechanisms, including the disk storage requirements, main memory requirements, response times for registration, and response time for querying. We also contrast performance to the accuracy of the mechanisms (how well they detect partial copies). The results are obtained using SCAM, an experimental server we have implemented, and a collection of 50,000 netnews articles.
Active immunity to Pneumocystis carinii reinfection in T-cell-depleted mice (1995)

Immunocompetent C.B-17 mice were immunized against Pneumocystis carinii by several intratracheal inoculations with infective P. carinii. These mice and another group of C.B-17 mice naive to P. carinii were then depleted of CD4+ cells by treatment with both anti-CD4 and anti-Thy1 monoclonal antibodies. Both groups of mice were then challenged with an infective inoculum containing 10(7) P. carinii organisms by intratracheal instillation. The mean log10 counts of P. carinii nuclei in the lungs of the nonimmune mice were 4.98, 5.89, and 6.77 when they were killed at 4, 10, and 19 days, respectively, after challenge. The P. carinii counts in the lungs of the immune mice were significantly lower at each time point and below detectable levels at 10 and 19 days. Analysis of P. carinii DNA by PCR revealed no detectable P. carinii in the lungs of the immunized mice at either 10 or 19 days, whereas all of the nonimmunized mice contained P. carinii DNA at all time points. The sera of immune but not nonimmune mice contained P. carinii-specific immunoglobulin G. These results indicate that immunization of an immunocompetent host against P. carinii can protect against P. carinii pneumonia even after the host is depleted of CD4+ cells. In addition, the results are consistent with the possibility that antibodies were responsible for the observed protection against P. carinii.
Relationship between growth of Escherichia coli and susceptibility to the lethal effect of paraquat (1990)

Paraquat, which mediates increased O2- production within Escherichia coli, inhibits growth without causing cell death in a minimal medium, whereas it allows growth while decreasing viability in a rich medium. Agents or conditions that inhibit growth in the paraquat-containing rich medium prevent this loss of viability. Antibiotics, chelating agents, nutritional paucity, and excess paraquat all acted this way. NaCl added to 0.2 M to the plates used for enumeration after paraquat exposure did not significantly decrease viable cell counts, although it did so after exposure to a cationic detergent. DNA, rather than cell membranes, thus seems to be a more likely target for the oxygen-derived free radicals engendered by the cycles of enzymatic reduction and autoxidation of paraquat. Inhibition of growth decreases the likelihood that DNA replication will precede DNA repair. Investigators seeking to evaluate the bactericidal actions of paraquat under a variety of conditions will need to be cognizant of this need for growth.
EXTRAHEPATIC HUGE BILOMA FROM RIGHT HEPATIC DUCT DUE TO BLUNT HEPATIC INJURY -A CASE REPORT AND REVIEW OF JAPANESE LITERATURE- (1995)

A 54-year-old Japanese man was admitted to the hospital with a diagnosis of blunt hepatic injury, which was deep laceration with tissue necrosis, due to a traffic accident. On admission, the patient was hemodynamically stable, without any evidence of peritonitis. He was treated conservatively. Thereafter, his abdomen was distended gradually. On the 20th hospital day, ultrasonograms, computed tomograms and US guided needle aspiration revealed an extrahepatic biloma. A drainage catheter was placed in the biloma percutaneously. However, the biloma extended from the right subphrenic cavity to the floor of pelvis. On the 71st hospital day, the biloma was resected with a T-tube drainage into the common bile duct. The injured site of the bile duct could not be determined at laparotomy. Postoperative cholangiograms performed via the T-tube catheter revealed bile leakage from the right hepatic duct. On the 65th postoperative day, follow-up cholangiograms demonstrated choledocholithiasis and an injured site of the hepatic duct, which was healed conservatively. choledocholithotomy under cholangioscopy through the T-tube fistula was performed for stones in the choledochus. We present a patient with extrahepatic biloma due to a blunt hepatic injury which is very rare, together with a review of the Japanese literature.
Esmolol cardioplegia in unstable coronary revascularisation patients (2000)

Esmolol addition to blood cardioplegia did not increase the efficacy of cardioprotection in the present study setting in unstable patients during urgent coronary revascularisation.
Selectively Nonselective Kinase Inhibition: Striking the Right Balance (2009)

ADVERTISEMENT RETURN TO ISSUEPerspectiveNEXTSelectively Nonselective Kinase Inhibition: Striking the Right BalanceRichard Morphy†View Author Information Medicinal Chemistry Department, Schering-Plough, Newhouse, Lanarkshire, ML1 5SH, U.K.†Contact information. Phone: 01698-736104. Fax: 01698-736187. E-mail: [email protected]Cite this: J. Med. Chem. 2010, 53, 4, 1413–1437Publication Date (Web):October 27, 2009Publication History Received30 July 2009Published online27 October 2009Published inissue 25 February 2010https://pubs.acs.org/doi/10.1021/jm901132vhttps://doi.org/10.1021/jm901132vreview-articleACS PublicationsCopyright © 2009 American Chemical SocietyRequest reuse permissionsArticle Views11840Altmetric-Citations247LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Inhibition,Inhibitors,Kinase inhibitors,Peptides and proteins,Selectivity Get e-Alerts
The ESCRT machinery regulates Akt signaling mediated by the G protein‐coupled receptor CXCR4 (2013)

The chemokine receptor CXCR4/stromal cell‐derived factor (SDF)‐1 alpha signaling axis is important in health and disease. Dysregulated CXCR4 signaling has been linked to cardiovascular disease, WHIM syndrome and cancer. However, despite the role of aberrant CXCR4 signaling in disease, the molecular mechanisms that govern CXCR4 signaling are poorly understood. The objective of this study is to elucidate the molecular mechanisms that govern CXCR4 signaling. Activated CXCR4 is rapidly ubiquitinated and sorted for lysosomal degradation via the endosomal sorting complex required for transport (ESCRT) machinery. The ESCRT machinery (ESCRT‐0, I, II and III) act in a coordinated manner to target ubiquitinated membrane proteins into intraluminal vesicles of multivesicular bodies for subsequent lysosomal degradation. While the ESCRT machinery mediates downregulation of CXCR4, our data indicate that it also has a novel positive role in CXCR4 signaling. Here, we provide evidence that the ESCRT machinery mediates CXCR4‐induced activation of Akt. Our data indicate that depletion of ESCRT‐0, I and II by siRNA inhibits CXCR4‐induced phosphorylation of Akt on serine 473, which corresponds to a decrease in Akt activity as phosphorylation of Tsc2, an Akt substrate, is also reduced. We show that Tsg101 (an ESCRT‐I subunit) interacts directly with Akt and under basal conditions Tsg101 and Akt are constitutively associated, as assessed by co‐immunoprecipitation; CXCR4 activation disrupts this interaction. Our data also reveal that CXCR4 internalization is required for Akt activation. Therefore CXCR4‐induced Akt activation is mediated by CXCR4 internalization onto endosomes and by the ESCRT machinery. This work was supported by grants from the AHA and the NIGMS.