gebhart/patrepeval huggingface dataset:
Quantification of bioactive constituents and determination of free radical scavenging activity in mangosteen fruit rind extracts (2007)

The pericarp of mangosteen (Garcinia mangostana L., Guttiferae) has been used as dyeing agent and traditional medicine, e.g. as antidiarrhoea and antidysentery agent and for the treatment of wounds [1]. In this study, the content of bioactive constituents and free radical scavenging activity of unripe and ripe fruit rinds of G. mangostana were determined and compared. Ethanolic extracts of the unripe and ripe fruit rinds were examined for the content of total phenolic compounds, total flavonoids, and total tannins using Folin-Ciocalteu procedure [2], aluminium chloride colorimetric method [3], and protein precipitation method [4], respectively. The results showed that the content of total phenolic compounds (42.57±0.11g GAE/100g extract) and total tannins (51.25±0.20g TAE/100g extract) in unripe fruit rind extract were higher than in the ripe fruit rind extract, while the highest content of total flavonoids was found in the extract of ripe fruit rind (4.08±0.07g QE/100g extract). Validated analytical methods, i.e., TLC-densitometry and HPLC, were developed for determination of α-mangostin contents in unripe and ripe fruit rinds of G. mangostana. The highest content of α-mangostin was found in the ripe fruit rind extract (16.65±0.38% w/w by TLC-densitometry, and 13.63±0.06% w/w by HPLC). Free radical scavenging activity was evaluated from EC50 value using DPPH scavenging method. The unripe fruit rind extract gave higher free radical scavenging activity (EC50, 5.56±0.12µg/ml). This study demonstrates differences in the content of chemical components and free radical scavenging activity between unripe and ripe fruit rinds of G. mangostana. This work also compared the content of α-mangostin in the fruit rind extracts using different analytical methods; TLC-densitometry, and HPLC. These methods are useful for quantitative analysis of α-mangostin in raw materials, extracts, pharmaceuticals, and cosmetic products from this plant.
The authors reply (2020)

Lyons, Patrick G. MD; Edelson, Dana P. MD, MS; Churpek, Matthew M. MD, MPH, PhD Author Information
Positioning Control between Pulses Using Sliding Mode Control (2009)

In this paper, we propose a method in which sliding mode control is used for improving position control. In industrial equipments, a pulse encoder is generally used for the determination of their positions, but the positions determined are unstable due to quantization errors that vary with the resolution of the encoder. It is known that this problem can be solved by employing an analog clamp method that uses two analog sinusoidal signals. However, the transmission capacity increases when the analog signals are transmitted serially.Therefore, we propose an analog clamp controller that can be used for determining a control condition on a sliding mode plane. Experiments confirm the effectiveness of the proposed method.
Strong Coupling State on Plasmonic Lattice Structures Under Electrochemical Potential Control (2020)

The collective oscillation of free electrons in the metal nanostructures induced by the visible light illumination is recognized as the localized surface plasmon (LSP). The coherent light energy exchange between excitons of molecules and LSP can modulate not only the absorption characteristic but also the individual energy decay. This reversible light energy exchange process between LSP and molecular exciton is called as the strong coupling regime. Although the strong coupling can allow use the light energy efficiently, the relative short lifetime of LSP due to the energy dissipation via the radiative damping limits the application. On the other hand, the surface lattice plasmon (SLR) mode which is excited on the two dimensionally arranged metal nanoparticles shows the longer excited lifetime because the diffractive light scattered from each particle is used for the excitation of the LSP at neighboring nanoparticle, resulting in the suppression of the scattering loss. As we demonstrated in our previous study, we have successfully achieved the fine electrochemical structure control method for obtaining the longest lifetime of the SLR mode. From these backgrounds, in this study, we have fabricated the Au lattice structure on a conductive glass and to support organic dye molecules on it to achieve the strong coupling regime. Through the extinction and fluorescence measurements, we have successfully observed the peak splitting which was originated from the formation of the strong coupling. In addition, by the combination of electrochemical method, we have confirmed our successful results for the reversible tuning of the coupling strength. From all experiments, we have successfully estimated the number of the molecules contributing to the strong coupling state. [1] H. Minamimoto et al., Phys. Chem. C 2018, 122, 14162.
PROPRIETES OPTIQUES DES NITRURES ET CARBONITRURES DE TITANE - SELECTIVITE SPECTRALE (1981)

On présente des résultats préliminaires sur l'évolution des propriétés optiques des nitrures et des carbonitrures de titane avec leur composition. On montre que les résultats obtenus sont conformes à un modèle de leur structure électronique qui permet d'orienter les recherches vers la synthèse de matériaux plus sélectifs.
Extended state estimation of nonlinear modeled induction machines (2003)

The authors report on the extended state estimation of induction machines. Based on a smoothly nonlinear machine model, local observability is analyzed for operation both with and without a speed sensor. An extended Kalman filter is designed so as to estimate not only electromagnetic quantities and the rotation speed, but also the load torque. Simulations demonstrate its excellent performance for sensorless field-oriented control.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Struma Ovarii With Hyperthyroidism (2017)

We report the case of a 61-year-old woman with persistent thyrotoxicosis for 7 years despite low thyroidal radioiodine uptake and methimazole treatment. Her initial I whole-body scan (WBS) was read as negative. Upon evaluation in our institution, she remained hyperthyroid after discontinuation of methimazole. Repeat WBS with SPECT/CT revealed low 24-hour thyroidal uptake (RAIU = 2%) and intensely focal radioiodine uptake in a large heterogeneous left pelvic mass, consistent with left adnexal struma ovarii. Resection of this mass confirmed benign struma ovarii. This case illustrates the advantage of fusion SPECT/CT imaging with planar I-WBS for diagnosis of extrathyroidal thyrotoxicosis.
Using memorization to achieve polynomial complexity of purely functional executable specifications of non-deterministic top-down parsers (1994)

article Free Access Share on Using memorization to achieve polynomial complexity of purely functional executable specifications of non-deterministic top-down parsers Author: R. A. Frost School of Computer Science, University of Windsor, Windsor, Ontario, Canada N9B 3P4 School of Computer Science, University of Windsor, Windsor, Ontario, Canada N9B 3P4View Profile Authors Info & Claims ACM SIGPLAN NoticesVolume 29Issue 4April 1994 pp 23–30https://doi.org/10.1145/181761.181764Published:01 April 1994Publication History 4citation165DownloadsMetricsTotal Citations4Total Downloads165Last 12 Months8Last 6 weeks3 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my Alerts New Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
STUDIES ON THE CHITAN (CHITIN: POLY-N-ACETYLGLUCOSAMINE) FIBERS OF THE DIATOM THALASSIOSIRA FLUVIATILIS HUSTEDT: I PRODUCTION AND ISOLATION OF CHITAN FIBERS (1965)

Growth of the planktonic, euryhaline diatom (Bacillariophyceae) Thalassiosira fluviatilis, both in nature and in culture, is accompanied by the production of a large amount of extracellular "mucilage". This mucilagenous condition is due to the formation of long, narrow fibers, composed of a number of microfibrils, which originate from the marginal and central pores in the silica valves. These fibers, previously referred to as mucilage or slime threads, were found upon hydrolysis to be composed entirely of glucosamine residues. Evidence will be presented in a subsequent paper (20) to show that these fibers consist entirely of pure, crystalline poly-N-acetyl-D-glucosamine linked by β-(1→4) bonds. This polymer has been given the systematic name chitan to distinguish it from chitin as isolated from other sources. This is the first report of the occurrence of this glycan in diatoms, and in a pure crystalline state in nature. The chitan was localized in the extracellular fibers, and was not found as part of the protoplasmic constituents. Approximately 18% of the nitrogen added to the culture medium was incorporated into the chitan fibers, which, in turn, comprised 31–38% of the cellular material (including the silica) of this diatom. Methods of production and isolation of the fibers are described, together with a discussion of the nature of the fibers as derived from light and electron microscopic observations. The presence of chitin in other algae also is discussed.
Determination of Activities of Levofloxacin, Alone and Combined with Gentamicin, Ceftazidime, Cefpirome, and Meropenem, against 124 Strains of Pseudomonas aeruginosa by Checkerboard and Time-Kill Methodology (1998)

A total of 124 Pseudomonas aeruginosa strains were tested for synergy between levofloxacin and cefpirome, ceftazidime, gentamicin, and meropenem. Checkerboards yielded synergistic fractional inhibitory concentration (FIC) indices (< or =0.5) with 25 of 496 possible combinations. All other FIC indices were >0.5 to 2 (additive or indifferent), with no antagonism. Time-kill studies with 12 strains showed that levofloxacin (0.06 to 0.5 microg/ml) was synergistic with cefpirome, ceftazidime, gentamicin, and meropenem in 10, 9, 4, and 11 strains, respectively.
A Fault Injection Method for Testing Dependable Web Service Systems (2012)

Testing Web services performance and their Fault Tolerance Mechanisms (FTMs) are crucial for the development of today's applications. Testing the performance and FTMs of composed service systems is hard to measure at design time because service instability is often caused by the nature of the network. Using a real internet environment for testing is difficult to set up and control. We have developed a fault injection toolkit that emulates a WAN within a LAN environment between composed service components and offers full control over the emulated environments in addition to the ability to inject network-related and application specific faults. The tool also generates background workloads on the tested system for producing more realistic results. We describe an experiment that has been carried out to test the impact of fault tolerance protocols deployed at a service client by using our fault injection toolkit.
Semaglutide treatment and renal function in the SUSTAIN 6 trial (2019)

Semaglutide is a GLP1-RA for treatment of T2D. SUSTAIN 6 was a 2year CVOT conducted in subjects with T2D at high risk for CV events. The results showed that semaglutide-treated subjects had a significant 26% lower risk of major adverse CV events vs. those receiving placebo. This post hoc analysis assessed the effect of semaglutide on renal function and renal AE by baseline estimated glomerular filtration rate in SUSTAIN 6. Materials: Changes in renal function, UACR and acute renal AEs were assessed in subjects categorised by baseline eGFR (mL/min/1.73 m2: normal ≥90, mild impairment < 90, moderate impairment < 60 and severe impairment < 30).
Quantitative expansion of ES cell-derived myeloid progenitors capable of differentiating into macrophages (2006)

Macrophages participate in physiologic and pathologic processes through elaboration of distinct activation programs. Studies with macrophage cell systems have revealed much concerning the importance of this pleiotropic cell; however, these studies are inherently limited by three factors: heterogeneity of the target cell population, poor capacity to elaborate various activation programs, and lack of a genetically tractable model system for loss- and gain-of-function studies. Although definitive, hematopoietic lineages can be isolated from embryonic stem (ES) cells, these isolation procedures are inefficient and time-consuming and require elaborate cell-sorting protocols. We therefore examined whether myeloid precursors, capable of differentiating into macrophages, could be conditionally expanded in vitro. Here, we report methods for selective isolation and immortalization of ES cell-derived myeloid precursors by estrogen-regulated HoxA9 protein. Using this new macrophage differentiation system, an unlimited number of custom-designed macrophages with defined functional characteristics can be generated from any targeted ES cell. In combination with knockout or small interfering RNA knockdown technologies, this macrophage differentiation system provides a powerful tool for high throughput analysis of regulatory mechanisms controlling macrophage activation in health and disease.
PET Reconstruction With an Anatomical MRI Prior Using Parallel Level Sets (2016)

The combination of positron emission tomography (PET) and magnetic resonance imaging (MRI) offers unique possibilities. In this paper we aim to exploit the high spatial resolution of MRI to enhance the reconstruction of simultaneously acquired PET data. We propose a new prior to incorporate structural side information into a maximum a posteriori reconstruction. The new prior combines the strengths of previously proposed priors for the same problem: it is very efficient in guiding the reconstruction at edges available from the side information and it reduces locally to edge-preserving total variation in the degenerate case when no structural information is available. In addition, this prior is segmentation-free, convex and no a priori assumptions are made on the correlation of edge directions of the PET and MRI images. We present results for a simulated brain phantom and for real data acquired by the Siemens Biograph mMR for a hardware phantom and a clinical scan. The results from simulations show that the new prior has a better trade-off between enhancing common anatomical boundaries and preserving unique features than several other priors. Moreover, it has a better mean absolute bias-to-mean standard deviation trade-off and yields reconstructions with superior relative l<sup>2</sup>-error and structural similarity index. These findings are underpinned by the real data results from a hardware phantom and a clinical patient confirming that the new prior is capable of promoting well-defined anatomical boundaries.
<title>Diamond film polishing with argon and oxygen ion beams</title> (1990)

In our program for ion beam polishing of microwave-assisted chemical vapor deposited diamond films using a planarizing layer we have sought to develop the technique by polishing AT-cut quartz disks used in rate monitors as an intermediate objective. Using an argon ion beam and spin-coated photoresist as the planarizing layer we successfully reduced the peak-to-valley (p-v) surface roughness from 5 pm to 0. 2 pm. In the case of diamond films whose etch rate is minute under argon bombardment reactive oxygen ions constituted the beam. The planarizing overcoat designed so that its etch rate would match that of the diamond film was a mixture of photoresist and titanium-silica. With this combination we reduced the diamond films'' surface roughness from 6 jim and 1 pm to 217 nm and 35nm p-v and mis respectively. This successful diamond film polishing opens the field of infrared optics to these materials. 1.
Dynamic Sulfur Chemistry : Screening, Evaluation and Catalysis (2010)

This thesis deals with the design, formation and evaluation of dynamic systems constructed by means of sulfur-containing reversible reactions, in organic and aqueous media and under mild conditions. In a first part, the synthesis of thioglycoside derivatives, constituting the biologically relevant starting components of the dynamic systems, is described. In addition, the pD-profile of the mutarotation process in aqueous media for a series of 1-thioaldoses is reported and revealed an astonishing beta-anomeric preference for all the carbohydrate analogs under acidic or neutral conditions. In a second part, the phosphine-catalyzed or -mediated disulfide metathesis for dynamic system generation in organic or aqueous media is presented, respectively. The direct in situ 1H STD-NMR resolution of a dynamic carbohydrate system in the presence of a target protein (Concanavalin A) proved the suitability and compatibility of such disulfide metathesis protocols for the discovery of biologically relevant ligands. In a third part, hemithioacetal formation is demonstrated as a new and efficient reversible reaction for the spontaneous generation of a dynamic system, despite a virtual character of the component associations in basic aqueous media. The direct in situ 1H STD-NMR identification of the best dynamic beta-galactosidase inhibitors from the dynamic HTA system was performed and the results were confirmed by inhibition studies. Thus, the HTA product formed from the reaction between 1-thiogalactopyranose and a pyridine carboxaldehyde derivative provided the best dynamic inhibitor. In a fourth and final part, a dynamic drug design strategy, where the best inhibitors from the aforementioned dynamic HTA system were used as model for the design of non-dynamic (or “static”) beta-galactosidase inhibitors, is depicted. Inhibition studies disclosed potent leads among the set of ligands.
Based on AHP comprehensive evaluation of optical strapdown inertial navigation system (2011)

This article studies on hierarchy analysis method in comprehensive evaluation of optical strapdown inertial navigation system. From the angle of vessels' using, building the evaluation index system of optical strapdown inertial navigation system, and on the basis of this research, studying the comprehensive evaluation method of optical strapdown inertial navigation system. First of all, the article determines the index weight of optical strapdown inertial navigation system by hierarchy analysis method. This method provides basis of assessment and means of examination for the design of warship system. The quality and level of warship system in our country is further enhanced, but also which provides technical support to other research on evaluation of warship equipment.
Switching to a holistic perspective on semantic component models in building automation – tapping the full potential of automated design approaches (2019)

Building automation systems are vital for reducing both energy consumption and carbon footprint of modern buildings. However, the engineering of such building systems is becoming increasingly complex, such that automating the engineering tasks is inevitable. Therefore, semantic component models of high quality and high expressiveness are required. But, as of today, existing models suffer from focusing on isolated aspects, high effort for component model specification, and low expressiveness in terms of the provided model structures. To close this gap, this paper proposes to adapt a holistic approach for modeling components. Firstly, we investigate different dimensions of component aspects and their interrelations and secondly, we develop BA-GSem, a graph-based semantic component model for building automation. Using a case study of a multi-variant room control unit, we illustrate that the correctness of system design results can be determined more precisely when using the detailed semantic model BA-GSem. The results offer a suitable foundation for improving the quality of automated design approaches for building automation, thus facilitating the creation of modern and sustainable buildings.
ChemInform Abstract: New Chiral Phosphine—Phosphite Ligands in the Enantioselective Palladium‐Catalyzed Allylic Alkylation. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Protection Conferred by Neonatal Rotavirus Infection against Subsequent Rotavirus Diarrhea (1993)

A cohort of newborns in New Delhi who were nosocomially infected with rotavirus during their first days of life were followed twice weekly for 14-23 months to determine whether neonatal infection protected them against subsequent episodes of rotavirus diarrhea. Infection occurred in 60% by the fourth day of life, was asymptomatic, and was caused predominantly by an unusual rotavirus strain (G9 P11) not previously identified in humans. The 148 children with neonatal rotavirus infection had 46% fewer attacks of rotavirus diarrhea in the follow-up period than the 56 infants without nosocomial infection (0.23 vs. 0.42 episodes/child-year, P < .05). This protection was concentrated among infants in their first year of life and was not associated with a significant decrease in disease severity. Consideration of this strain as a vaccine candidate will require further assessment of its natural protection under field conditions.
Detection of anionic sites and immunoglobulin a deposits in the glomerular capillary walls from patients with Iga nephropathy (1989)

A study of anionic sites in the glomerular basement membrane (GBM) from patients with immunoglobulin A (IgA) nephropathy is described. The relationship between the deposition of IgA and the detection of glomerular extracellular components, i.e., noncollagenous (NC-1) domain of Type IV collagen, in the glomerular capillary walls was examined by double immunofluorescence. Renal biopsy specimens from patients with IgA nephropathy were immersed in polyethyleneimine (PEI) as a cationic probe and then examined by electron microscopy. Renal specimens were also incubated with mouse monoclonal anti-NC-1 domain of Type IV collagen and then stained with fluorescein isothiocyanate (FITC)-labelled goat antimouse Ig antiserum. After these reactions, sections were stained with rhodamine-labelled rabbit antihuman IgA antiserum. GBM subepithelial anionic sites marked by PEI were altered by the deposition of electron-dense deposits (EDD) in patients with IgA nephropathy and there was a significant correlation between the levels of proteinuria and the incidence of EDD in the GBM in such patients. Marked proteinuria was observed in patients who showed loss of anionic sites in the GBM by electron microscopy. By double immunofluorescence, IgA was shown to be focally deposited outside the NC-1 domain of Type IV collagen-detected regions in the same patients. The authors concluded that high levels of proteinuria might be due to alterations of the size barrier and/or anionic sites of GBM in the moderate stage of IgA nephropathy.