gebhart/patrepeval huggingface dataset:
Effect of edible coating on shelf life and quality of local mango cv. Rangkuai of Mizoram (2018)

Highly nutritious, delicious and attractive looking fruits of mango which are generally consumed fresh undergo high amount of post-harvest losses. An experiment was taken up to study the impact of different edible coatings viz., olive oil, wax, chitosan, carboxy methyl cellulose, aloe gel on shelf life and quality of local mango cv. Rangkuai collected from Saiha district of Mizoram; kept in ambient condition. Results of the experiment showed that fruit coated with wax remained dark green skin colour (L: 28.73, a: -18.55, b: 26.03) and pulp colour was slightly yellowish orange (L: 63.69, a: -2.38, b: 60.78), whereas fruit skin colour at control had slightly light green colour with yellowness (L: 35.87, a: -18.88, b: 38.58) with completely dark orange colour pulp (L: 44.21, a: 23.32, b: 52.34) at 12 days after storage (DAS). Waxed mango fruits had minimum weight loss (1.18%) and high amount of ascorbic acid (19.92 mg/100 g) and carotenoids (4.64 mg/100 g) even after 12 DAS. Maximum shelf life was observed in waxed mango (19.65 days) as the fruit decay was only 10.05%.
Selective Repression of Translation by the Brome Mosaic Virus 1a RNA Replication Protein (2006)

Differential expression of viral replication proteins is essential for successful infection. We report here that overexpression of the brome mosaic virus (BMV) 1a protein can repress viral RNA replication in a dosage-dependent manner. Using RNA replication-incompetent reporter constructs, repression of translation from BMV RNA1 and RNA2 was observed, suggesting that the effect on translation of the BMV RNA replication proteins is responsible for the decrease in RNA levels. Furthermore, repression of translation by 1a required the B box in the 5'-untranslated region (5' UTR); BMV RNA3 that lacks a B box in its 5' UTR is not subject to 1a-mediated translational inhibition. Mutations in either the methyltransferase or the helicase-like domains of 1a reduced the repression of replication and translation. These results suggest that in addition to its known functions in BMV RNA synthesis, 1a also regulates viral gene expression.
Orthogonal Functional Group Interconversion (2021)

Key words functional group metathesis - nickel catalysis - thioethers - nitriles
STM-Investigations on Heteroepitaxially Grown Over-Layers of Cu-Phthalocyanine on AU(111) Surfaces (1994)

6855bHeteroepitaxial growth of copper phthalocyanine (CuPc) on Au(111) surfaces has been confirmed for the first time by Scanning Tunneling Microscopy (STM). The combination of in situ electron diffraction (RHEED) with STM allows direct studies of heterogeneous layer growth, revealing a novel commensurable superstructure of the organic overlayer with the Au(111) surface. The organic molecular beam epitaxy (OMBE) technique has demonstrated that molecular orderings of CuPc monolayers can be controlled, resulting in artificial lattice structures in organic ultrathin films being different from those in bulk
Chimeric protein: abrin B chain-trypsin inhibitor conjugate as a new antitumor agent. (1989)

Abrin B chain and trypsin inhibitor isolated from Acacia confusa (ACTI) were covalently linked to form a chimeric protein (ANB-ACTI) with N-succinimidyl-3-(-2-pyridyldithio)propionate. The chimeric protein had 31% of trypsin inhibitory activity of ACTI and 7% of hemagglutinating activity of abrin B chain, but no inhibition on protein biosynthesis. ANB-ACTI had strong inhibitory effects on the growth of sarcoma 180 cells and Hela cell culture while the mixture of an equivalent amount of free abrin B chain and ACTI did not. The results suggests that abrin B chain of chimeric protein may act as a vector to carry ACTI into the tumor cells. ACTI into the tumor cells. ACTI in the chimeric protein potentiates its antitumor activity as well as its resistance to tryptic digestion.
Central Sympathoinhibition by Moxonidine Improves Prognosis in Rats with Hypertensive Heart Failure (2013)

Aim: Excessive sympathetic activity is associated with pathologies such as hypertension and heart failure (HF) [1]. Central sympathetic nervous system activity is an indicator of the prognosis of HF [2]. Although the central sympatholytic drug, moxonidine, is an established therapeutic strategy for hypertension [3], its benefits for hypertensive HF are poorly understood. The present study investigated the effects of central sympathoinhibition by moxonidine on hypertensive HF. Methods: As the model of hypertension-induced HF, we fed Dahl salt-sensitive (DS) rats with 8% NaCl diet from the age of 7 weeks [4]. Intracerebroventricular (ICV) infusion of moxonidine (Mox-ICV) or vehicle (Veh-ICV) was performed from 14 to 20 week-old, during the increased HF phase. We examined survival first of all, measured systolic blood pressure and heart rate with tail-cuff system and left ventricular (LV) function and remodeling by echocardiography every 2 weeks. And we measured 24-hour urinary norepinephrine excretion (uNE) as an index of sympathetic activity before and after the treatment. We also investigated LV performance by Millar catheter and pathological changes in LV at the end of the treatment. Results: Hypertension and pressure-overload LV hypertrophy were established by 13 week-old. At about 20 weeks of age, DS rats-treated with Veh-ICV experienced overt heart failure associated with sympathetic hyperactivity (Fig. 1). Mox-ICV treatment decreased uNE, suppressed LV dysfunction, remodeling and pathological changes compared with Veh-ICV treatment. Survival at 21weeks of age was significantly improved in DS rats-treated with Mox-ICV compared to Veh-ICV (76 vs. 23 %; p<0.05, n=17 and 28, respectively) (Fig. 2). Conclusion: Moxonidine-induced central sympathoinhibition prevented cardiac dysfunction and remodelling, and improved the prognosis in rats with hypertensive HF. Central sympathoinhibition can be effective for the treatment of hypertensive HF. References [1] Grassi G. Sympathetic neural activity in hypertension and related diseases. Am J Hypertens 2010; 23:1052-1060. [2] Francis GS. Neurohumoral activation and progression of heart failure: hypothetical and clinical considerations. J Cardiovasc Pharmacol 1998; 32:S16-S21. [3] Edwards LP, Brown-Bryan TA, McLean L, Ernsberger P. Pharmacological properties of the central antihypertensive agent, moxonidine. Cardiovasc Ther 2012; 30:199-208. [4] Doi R, Masuyama T, Yamamoto K, Doi Y, Mano T, Sakata Y et al. Development of different phenotypes of hypertensive heart failure: systolic versus diastolic failure in Dahl salt-sensitive rats. J Hypertens 2000; 18:111-120. Central sympathoinhibition by moxonidine improves prognosis in rats with hypertensive
Distinct bactericidal activities of bovine lactoferrin peptides LFampin 268–284 and LFampin 265–284: Asp-Leu-Ile makes a differenceThis paper is one of a selection of papers published in this Special Issue, entitled 7th International Conference on Lactoferrin: Structure, Function, and Applications, and has undergone the Journal's usual peer review process. (2006)

Two lactoferrampin (LFampin) peptides derived from bovine lactoferrin were compared with respect to their bactericidal activities. LFampin 265-284 killed a set of Gram-positive bacteria that were resistant to LFampin 268-284. The presence of 265Asp-Leu-267Ile did not simply lead to an overall increased potency, since higher concentrations of LFampin 265-284 than LFampin 268-284 were needed to kill the Gram-negative bacteria that were tested. The Asp-Leu-Ile sequence enhances the propensity of LFampin to adopt an alpha-helix, as shown by circular dichroism spectroscopy. These results suggest that the helical conformation of the peptide is an important determinant of the susceptibility of Gram-positive bacteria.
MAMAP – a new spectrometer system for column-averaged methane and carbon dioxide observations from aircraft: instrument description and performance assessment (2010)

Abstract. Carbon dioxide (CO2) and Methane (CH4) are the two most important anthropogenic greenhouse gases. CH4 is furthermore one of the most potent present and future contributors to global warming because of its large global warming potential (GWP). Our knowledge of CH4 sources and sinks is based primarily on sparse in-situ local point measurements from micro sites and surface networks and more recently on low spatial resolution satellite observations. There is a need for measurements of the dry columns of CO2 and CH4 having high spatial resolution and spatial coverage. In order to fill this gap a new passive airborne 2-channel grating spectrometer instrument for remote sensing of small scale and mesoscale column-averaged CH4 and CO2 observations has been developed. This Methane Airborne MAPper (MAMAP) instrument measures reflected and scattered solar radiation in the short wave infrared (SWIR) and near-infrared (NIR) parts of the electro-magnetic spectrum at moderate spectral resolution. The SWIR channel yields measurements of atmospheric absorption bands of CH4 and CO2 in the spectral range between 1.59 and 1.69 μm at a spectral resolution of 0.82 nm. The NIR channel around 0.76 μm measures the atmospheric O2-A-band absorption with a resolution of 0.46 nm. MAMAP has been designed for flexible operation aboard a variety of airborne platforms. The instrument design and performance, together with some results from on-ground and in-flight engineering tests are presented. The instrument performance has been analyzed using a retrieval algorithm applied to the SWIR channel nadir measured spectra. The signal-to-noise ratio (SNR) of the SWIR channel is approximately 1000 for integration times (tint) in the range of 0.6–0.8 s for scenes with surface spectral reflectances of around 0.18. At these integration times the ground scene size is about 23×33 m2 for an aircraft altitude of 1 km and a ground speed of 200 km/h. For these scenes the CH4 and CO2 column retrieval precisions are typically about 1% (1 σ). Elevated levels of CH4 have been retrieved above a CH4 emitting landfill. Similarly the plume of CO2 from coal-fired power plants can be well detected and tracked. The measurements by the MAMAP sensor enable estimates of anthropogenic, biogenic and geological emissions of localized intense CH4 and CO2 sources such as anthropogenic fugitive emissions from gas industry and waste, emissions from coal-fired power plants or geologic emissions from seepage and volcanoes. Appropriate analysis of the measurements of MAMAP potentially also yields CH4 emissions from less intense but extensive sources such as wetlands.
A generalized framework for learning and recovery of structured sparse signals (2012)

We report on a framework for recovering single- or multi-timestep sparse signals that can learn and exploit a variety of probabilistic forms of structure. Message passing-based inference and empirical Bayesian parameter learning form the backbone of the recovery procedure. We further describe an object-oriented software paradigm for implementing our framework, which consists of assembling modular software components that collectively define a desired statistical signal model. Lastly, numerical results for synthetic and real-world structured sparse signal recovery are provided.
Proposal of Transformerless Reactive Series Compensator with AC Switches (2000)

Since the Electric Power Research Institute in the U.S.A. (EPRI) proposed the FACTS (Flexible AC Transmission System) in 1988, R&D activities of the FACTS are intensively pushed by the liberalization of the power delivery system in the U.S.A. and the Central Europe. Especially, the Unified Power Flow Controller (UPFC) that has been developed by the EPRI and Westinghouse is one of the most functional devices. However, the UPFC has several problems because of having complex transformers. For example, it not only generates comparatively big power losses into the transformers but also has to prevent the magnetic saturation of the transformers. As an effective solution, the Transformerless Reactive Series Compensator (TLRSC) has been proposed. Some basic operations have been already described in detail. However, the TLRSC is directly series-connected with transmission lines and the line current always flows through the TLRSC. Therefore, such special operations as a pre-charging operation, a start-up/shut-down operation and a continuous operation must be considered to realize the TLRSC. In this paper, firstly, a new configuration of the TLRSC with AC switches is proposed. Next, it is focused that the AC switches can carry out the special operations. Finally, it is verified that the new TLRSC doesn't need any transformer at all.
A Shock-Tube Study on the Ignition Lag of Gaseous Fuels (1973)

A study was made on the ignition delays of n-butane-oxygen mixtures to clarify the high-temperature oxidation mechanism of gaseous higher-hydrocarbon fuels. The ignition delays were measured in a shock tube by detecting the visible emissoin from the reactants employed as driven gases. Experiments were carried out for various equivalence ratios and for a range of shocked-gas temperatures ancl pressures. Using n-butane-argon mixtures as driven gases of the shock tobe the cracking reaction, supposed to occur prior to ignition, were observed by means of the integrated schlieren method and the gas chromatography. A reaction model for the oxidation of n-butane was proposed, which was similar to the well-established reaction model for hydrogen-oxygen mixtures, and iginition delays were calculated on the basis of this reaction model. Calculated igniiotn delays and the dependence of the apparent activation energy on the equivalence ratios agreed fairly well with experimental results.
Management of acute otitis media (2009)

The present position statement updates a previous document released in 1998 (1). It is based on published evidence, and is intended to be a guide for sound clinical decision making. The present document is not intended for children with craniofacial abnormalities, immunocompromising conditions or complicated acute otitis media (AOM), or newborns younger than eight weeks of age. Why do children get AoM? AOM is extremely common in children – in fact, 75% of children have at least one episode by one year of age (2). The primary defect leading to AOM is eustachian tube dysfunction and obstruction. Compared with adults, children are predisposed to AOM because their eustachian tubes are shorter, more horizontal and more prone to obstruction by enlarged adenoids (3,4). Furthermore, viral infections and allergies are common in young children, and both can cause eustachian tube inflammation (5,6). Finally, children (especially those with recurrent otitis media) may have decreased levels of secretory immunoglobulin A – an antibody that decreases bacterial adherence in the nasopharynx (7). Once the eustachian tube is obstructed, two things happen. First, mucociliary clearance is impaired, trapping mucus in the middle ear space (8). Second, resorption of gases within the middle ear space creates a pressure differential, akin to a vacuum, which pulls bacteria from the nasopharynx into the middle ear space. Once introduced into this space, bacteria can proliferate and may cause a secondary infection. Thus, it is rare to develop AOM without an antecedent viral upper respiratory tract infection, with AOM typically developing after several days of viral symptoms. Are cert Ain children At higher risk for AoM? The major risk factors for AOM are young age and daycare attendance. The former is likely related to the anatomy of the eustachian tube and low secretory immunoglobulin A levels, while the latter is related to increased exposures to viral infections, coupled with an increased incidence of nasopharyngeal colonization with pathogenic bacteria. Other risk factors include orofacial abnormalities (such as cleft palate), household crowding, exposure to cigarette smoke, premature birth, not being breastfed, immunodefi
<title>Video retrieval method using shotID for copyright protection systems</title> (1998)

In this paper, we define a shot-identifier (we called this shotID) which easily represents characteristics of each shot. The shotID is calculated from positional and color information. And we propose a video retrieval method using the shotID. The proposed method is robust to compression, format conversion, frame dropping and noise such as watermark and so on. Furthermore, we realize a copyright protection system for digital video with watermarking technique using ideas from spread spectrum communications based on our retrieval method.
Cloning and identification of saprolmycin biosynthetic gene cluster fromStreptomycessp. TK08046 (2016)

Saprolmycins A-E are anti-Saprolegnia parasitica antibiotics. To identify the gene cluster for saprolmycin biosynthesis in Streptomyces sp. TK08046, polymerase chain reaction using aromatase and cyclase gene-specific primers was performed; the spr gene cluster, which codes for angucycline biosynthesis, was obtained from the strain. The cluster consists of 36 open reading frames, including minimal polyketide synthase, ketoreductase, aromatase, cyclase, oxygenase, and deoxy sugar biosynthetic genes, as defined by homology to the corresponding genes of the urdamycin, Sch-47554, and grincamycin biosynthetic gene clusters in Streptomyces fradiae, Streptomyces sp. SCC-2136, and Streptomyces lusitanus, respectively. To establish the function of the gene cluster, an expression cosmid vector containing all 36 open reading frames was introduced into Streptomyces lividans TK23. The transformant was confirmed to express the biosynthetic genes and produce saprolmycins by liquid chromatography-mass spectrometry analysis of the extract.
Anisotropic atom-surface interactions in the Casimir-Polder regime (2014)

The distance dependence of the anisotropic atom-wall interaction is studied. The central result is the $1/{z}^{6}$ quadrupolar anisotropy decay in the retarded Casimir-Polder regime. Analysis of the transition region between nonretarded van der Waals regime (in $1/{z}^{3}$) and Casimir-Polder regime shows that the anisotropy crossover occurs at very short distances from the surface, on the order of $0.03\ensuremath{\lambda}$, where $\ensuremath{\lambda}$ is the atom characteristic wavelength. Possible experimental verifications of this distance dependence using surface-induced inelastic transitions are discussed.
Management Information Base for the User Datagram Protocol (UDP) (2005)

This memo defines a portion of the Management Information Base (MIB) for use with network management protocols in the Internet community.In particular, it describes managed objects used for implementations of the User Datagram Protocol (UDP) in an IP version independent manner.This memo obsoletes RFCs 2013 and 2454.
Full wave analysis and design of RF tunable filters (2002)

In this paper, a systematic design method for the finline structure tunable filter is presented based on filter synthesis and the full wave analysis using Ansoft EM simulation software HFSS. The varactor effects have been discussed. Two filter examples, one in Ka- and the other in K-band, are built and tested to verify the design. The measurement results are in agreement with the simulations.
In vitro Susceptibility of Pseudomonas aeruginosa from Bacteremic and Fibrocystic Patients to Four Quinolones and Five Other Antipseudomonal Antibiotics (1988)

The in vitro antibacterial activities of 4 quinolones, 4 antipseudomonal beta-lactam antibiotics and tobramycin were determined by an agar dilution technique against 206 clinical isolates of Pseudomonas aeruginosa. 176 isolates derived from blood cultures (BC), the remaining 30 were piperacillin-resistant strains from sputum of cystic fibrosis (CF) patients. The CF strains were more resistant to all drugs tested and differed greatly in susceptibility pattern from the BC strains. Ciprofloxacin, ofloxacin and tobramycin were the most active drugs against the CF strains. More than 80% of the BC strains were susceptible to piperacillin and cefsulodin and more than 90% to ceftazidime, tobramycin, ciprofloxacin and ofloxacin. On a weight basis ciprofloxacin was the most active drug in both groups of strains. Our in vitro data suggest that several valuable drugs are now available in the treatment of infections caused by P. aeruginosa strains not previously exposed to antipseudomonal agents.
Insights into How Mutations Thermostabilize G-Protein-Coupled Receptors (2016)

207-Plat Crystal Structure of the Calcium ATPase SERCA in Complex to a Novel Anti-Cancer Agent that Targets Multidrug-Resistant Leukemia John K. Lee1, Joseph M. Autry1, Razvan Cornea1, Nicholas Bleeker2, Denise Casemore2, Chengguo Xing2, David D. Thomas1. Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA, Department of Medicinal Chemistry, University of Minnesota, Minneapolis, MN, USA. We have used x-ray crystallography to solve the crystal structure of the sarco/ endoplasmic reticulum Ca-ATPase (SERCA) in complex with a novel lead compound (CXL017) that targets multidrug-resistant leukemia (Hermanson et al., Mol Pharmacol 2009). The structure, solved at 3.01A resolution, reveals CXL017 bound to SERCA near the ATP binding site and suggests blockage of the ATP channel as the main mechanism of inhibition. This result confirms that CXL017 binds SERCA at a location that is distinct from the binding sites of other inhibitors of SERCA, and it explains the synergistic relationship that was uncovered between CXL017 and classic SERCA inhibitors (Bleeker et al., Mol. Pharmacol 2013). Further, it provides the platform for structureguided improvements on this new class of potential anti-cancer agent. This work was funded by a grant from NIH to DDT (R01 GM27906) and a grant from NIH to XC (R01 CA163864).
IC-Compatible Polysilicon Surface Micromachining (2000)

▪ Abstract Polysilicon surface micromachining is advancing significantly and many new applications are moving beyond the prototyping phase. Recent technical successes are leading to excitement concerning various uses of devices in optical, wireless, sensor, and many other areas. Incorporation of state-of-the-art integrated circuit (IC) fabrication methods, such as planarization by chemical mechanical polishing (CMP), has enabled extension to a five-level technology. This has opened significant design space, especially for microactuator applications. Recent advancement of in situ microdiagnostics for materials and surface properties has enhanced our understanding of device reliability and performance and will allow devices to operate near well-known materials limits. New IC-compatible materials will further enhance the capabilities of microsystems in terms of performance, reliability, and operation in harsh environments.
Poster Paper Impact Of Software Stack Version On Micro-architecture (2019)

Open source Big Data frameworks such as Spark have been evolvingquite rapidly. Many of the changes have addressed improvement inperformance mainly focusing on the performance of the entire job executing on a distributed system. Past studies have reported micro-architectural performance characteristics of benchmarks based onthese Big Data frameworks. Given the rapid changes to these frame-works, it is expected that some of these code changes will also have amicro-architectural impact. In this paper, we present a comparativestudy of performance of Apache Spark across two major revisions and demonstrate that there are micro-architectural differences in the way the applications use the hardware.