gebhart/patrepeval huggingface dataset:
Growing occult synchronous adrenal metastasis from rectal cancer after surgery and during adjuvant chemotherapy: A Case Report (2010)

Abstract We report a case of an occult synchronous adrenal metastasis of rectal cancer. A left adrenal mass was found by computed tomography (CT) 6 months after low anterior resection for rectal cancer. This lesion was growing during adjuvant systemic chemotherapy. The level of serum carcinoembryonic antigen and that of adrenal hormones were within the normal range. Radical left adrenalectomy was performed, and histopathological examination revealed metastatic adenocarcinoma compatible with rectal cancer. Adrenal metastasis is not rare in autopsy series. The possibility of adrenal metastasis should be considered in the follow-up of rectal cancer patients. Surgery may be the treatment of choice in occult synchronous metastasis of adrenal gland in rectal cancer.
Predictions of flow and heat transfer in sharp 180-deg turns of gas turbine coolant channels with and without turning vanes (1999)

A numerical study was conducted to determine the effects of turning vanes on the flow characteristics, the pressure drop and the heat transfer distribution in the turn region of two-legged, coolant passages for application to cooling gas turbine blades. The channels consisted of two straight, square-sectioned legs connected by a 180-deg. turn, with an inner radius of 0.15 hydraulic diameters. The ribs were square-sectioned with a height of 0.1 D{sub h}, staggered between leading and trailing side and at an angle of 45-deg. to the flow. Three different configurations of the coolant channel were investigated: with smooth walls, with ribs on two walls and no vane and with ribs on two walls and a 180-deg guide vane in the turn. For all calculations, the Reynolds number at the inlet was Re{sub D} = 100,000, the fluid was water and buoyancy effects were neglected. The simulations were made for rotation numbers, Ro = 0.0 and 0.15. The flow and heat transfer simulations were made with the FLUENT structured code. Based on the results of several previous studies, the differential-Reynolds-Stress turbulence model with wall functions was used. The highest heat transfer in the turn was obtained for both the rotating and non-rotatingmore » cases with the ribbed channel without the guide vane. The pressure loss was also higher without the vane. Due to the staggering of the ribs, secondary flow and heat transfer in the turn was higher on the side of the channel where the last rib at the entrance reaches further into the turn. With increasing rotation number, the secondary flow and heat transfer increased on the leading side of the turn. For the configuration with a 180-deg. vane, the mass flux at the outer side of the vane increased with increasing rotation number.« less
Bacteria and pH-Sensitive Polysaccharide-Polymer Films for Colon Targeted Delivery (2011)

The colon provides drug delivery opportunities for colon-specific and systemic delivery of various therapeutic agents. Different strategies have been utilized in targeting drugs to the colon. Recently, integrated systems which incorporate dual mechanisms in colon targeted delivery have received a lot of attention. Of particular interest is bacteria-aided biomaterials and pH-sensitive polymeric film (BPSF) coating for colon targeted drug delivery. The major constituents of these films are polysaccharides and pH-sensitive polymers. The pH-sensitive polymer retards drug release in the stomach and small intestine, while the polysaccharide is digested by colonic enzymes. Digestion of the polysaccharides by bacterial glycosidic enzymes increases the pore density in the film to facilitate drug release. Generally, bacteria-aided biomaterials and pH-sensitive films can be applied to the delivery of most small organic molecules to the colon. The review encompasses the pharmaceutical design parameters such as film digestibility, swelling index and dry mass loss (that provide molecular mechanistic analysis of film permeability) as well as tensile strength, elastic modulus, and elongation at break (that describe the desirable mechanical properties of the films). A critical analysis of formulation, techniques for characterization of film properties and drug-release kinetics from these systems are emphasized.
Chronic Obstructive Pulmonary Disease: pocketbook (2023)

This book provides an up-to-date perspective on the inflammatory cells, mediators, and molecular pathology of Chronic obstructive pulmonary disease (COPD), emphasizing the urgent need to clearly understand the underlying cellular and molecular mechanisms involved in COPD.
Anomalous hydrogen-1 and carbon-13 spectra of some new N-acyl-N′-aryldiazene complexes of osmium (1975)

The complex [OsCl3O(PPh3)2] reacts with the hydrazides 4-RC6H4NHNHCOR′(R = MeO, Me, H, Cl, or NO2; R′= H, Me, Et, Prn, But or CH2Ph) to give the N-acyl-N′-aryldiazene complexes [OsCl2(4-RC6H4·N2·COR′)(PPh3)2]. Although apparently diamagnetic, their 1H and 13C n.m.r. spectra show shifts of a pattern and magnitude characteristic of paramagnetic species. Moreover these shifts are restricted to certain protons and carbon atoms of the diazene ligand, and the tertiary phosphine protons and carbon atoms show no anomalies. The magnitude of the shifts is highly dependent on the nature of the substituents in the diazene N-phenyl group, and there is an approximately linear relation between the shifts and Hammett σ constants for the substituent. Variable-temperature 1H n.m.r. spectra suggest that a second-order paramagnetic effect may be responsible for the shifts.
Identification and analysis of single nucleotide polymorphisms in the myosin VA (MYO5A) gene and its exclusion as the causative gene of the dilute coat colour locus in rabbit (2012)

Classical genetic studies have identified different coat colour loci in rabbit and comparative analyses have established corresponding loci across species. In particular, the rabbit dilute locus is determined by a recessive coat colour mutation that modifies the basic colours influenced by the agouti and extension mutations. In mice, similar phenotypic effects are determined by a similarly named locus. This locus encodes the myosin VA (Myo5a) gene, whose protein product is an unconventional myosin that plays an essential role in melanosome transport in the melanocytes. We selected the same gene as a strong candidate for explaining the dilute coat colour in rabbit. To this end, 1399 bp were re-sequenced, spanning 4 exons out of 41 exons and a portion of intronic regions of the rabbit MYO5A gene to identify polymorphisms that could be useful to confirm or exclude this gene as causative of the rabbit dilute locus. Nine polymorphisms were identified, one of which was used to follow the segregation of the blue and black colours in a Checkered Giant F1 family. The single nucleotide polymorphism (SNP) analysed did not co-segregate with the two colours. These results excluded the MYO5A gene as determinant of the dilute locus in rabbit. The two alleles of this SNP were also present in several other breeds with different coat colours, further indicating that this marker is not associated with the dilute mutation in rabbits. Other candidates should be investigated to identify the causative gene of this locus in rabbit.
Oxalate and Oxalate Oxidase in Malt (2009)

Barley kernels contain a single oxalate oxidase located in the embryo and aleurone. It is already present in substantial quantities in unmalted grain and increases in activity during germination. It displays a very broad pH optimum: the optimum was at pH 4.0, but the enzyme still displayed more than 50% of its activity at pH 7. Oxalate oxidase is highly resistant to heat. However, its low affinity for oxygen suggests that it probably does not play a major role in the consumption of oxygen in mashing. The decrease in oxalic acid levels late in germination may be a result of oxalate oxidase action. Oxalic acid was not detected in raw barley.
Comment on Suissa. Lower Risk of Death With SGLT2 Inhibitors in Observational Studies: Real or Bias? Diabetes Care 2018;41:6–10 (2018)

Comment on Suissa. Lower Risk of Death With SGLT2 Inhibitors in Observational Studies : Real or Bias? Diabetes Care 2018;41:6–10
Proposed of cultivation management system with informatics and communication technology (2012)

Recently, many of agricultural-work pursuers are recording agricultural-work record on the paper basis. These situation based on paper recording has difficulty to check the past agricultural-work data and the cost control of agricultural products, compared to electrically stored data. Many farmhouses want to manage agricultural-work information, in order to grasp the cost price. Furthermore, the needs for the systematization of cultivated land management from many farming people in Japan So, in this study, we propose cultivated land management system in order to solve these problems. This system stores the agricultural-work data into electrical database through the Web browser.
The role of taxanes in triple-negative breast cancer: literature review (2015)

Breast cancer (BC) is the most frequent tumor worldwide. Triple-negative BCs are characterized by the negative estrogen and progesterone receptors and negative HER2, and represent 15% of all BCs. In this review, data on the use of taxanes in triple-negative BCs are analyzed, concluding they are effective in any clinical setting (neoadjuvant, adjuvant, and metastatic). Further, the role of nab-paclitaxel (formulation of albumin-bound paclitaxel) in these tumors is also evaluated. The available data show the clinical potential of nab-paclitaxel based combinations in terms of long-duration response, increased survival, and better quality of life of patients with triple-negative metastatic BC. The ongoing trials will give further information on the better management of this type of tumor.
Cobalt(III) Complexes of [35]Adamanzane, 1,5,9,13-Tetraazabicyclo[7.7.3]nonadecane. Report of an Inert, Chelate Hydrogen Carbonate Ion (2001)

Three cobalt(III) complexes of the macrocyclic tetraamine [3(5)]adamanzane (1,5,9,13-tetraazabicyclo[7.7.3]nonadecane) were isolated as salts. The X-ray crystal structures were solved for the compounds [Co([3(5)]adz)(CO(3))]AsF(6) (1b), [Co([3(5)]adz)(HCO(3))]ZnBr(4).H(2)O (2a), and [Co([3(5)]adz)(SO(4))]AsF(6).H(2)O (3a). The coordination geometry around the cobalt(III) ion is a distorted octahedron with the inorganic ligands at cis-positions. Complex 2 is the second example of a cobalt(III) complex for which the X-ray structure shows a chelate binding mode of the hydrogen carbonate entity. The pK(a) value of the [Co([3(5)]adz)(HCO(3))](2+) ion (2) was determined spectrophotometrically to be 0.27 (25 degrees C, I = 5.0 M). The protonation appears to occur at the noncoordinated carbonyl oxygen atom of the carbonate group, with hydrogen bonding to the crystal water molecule. Evidence is presented for this oxygen atom as the site of protonation in solution as well. In 5.0 M CF(3)SO(3)H a slow reaction of the carbonato complex, quantitatively yielding the [Co([3(5)]adz)(H(2)O)(2)](3+) ion, was observed. k(obs) = 7.9(1) x 10(-)(6) s(-)(1) at 25 degrees C.
Clinical coding support based on structured data stored in electronic health records (2012)

Clinical coding is an increasingly essential process within health organizations, usually performed manually and entailing several challenges: its administrative burden, raising costs and eventual errors. To address this issue, several coding support systems have been proposed across the literature. However, these systems are based on text processing methods that may be limited by poor text quality, ambiguity and lack of annotated resources. As electronic health record systems tend to implement more structured data formats, we propose a methodology for coding support based on structured clinical data collected during inpatient care from a semi-structured electronic health record. We follow a statistical learning paradigm and investigate several building blocks of the methodology to assess the feasibility of the approach. We present and discuss preliminary results obtained with real data extracted from an Internal Medicine department and identify several measures to further develop the methodology, model performance and generalizability.
Nonlinear Dynamics of a Passively Mode-Locked Fiber Laser Containing a Long-Period Fiber Grating (2008)

We report on a numerical investigation of the nonlinear dynamics of a passively mode-locked fiber laser containing a long period fiber grating. The model is based on the normalized complex Ginzburg-Landau equation and the nonlinear coupled mode equations of the grating. The numerical results indicate the existence of passive mode-locking and autosoliton generation in the cavity of the laser. Both single and bound soliton pulse trains exhibit period doubling bifurcations and a route to chaos as the normalized saturated gain is increased. Furthermore, we show the presence of long period pulsation, soliton sidebands and possible coexisting attractors excited by multisoliton formation and soliton energy quantization.
User-interface developments for the nineties (1991)

The purpose and history of user interfaces are briefly recounted. The language model and the implementation model of the user-computer dialogue are examined. User-centered design is discussed, and approaches to design tools are described. Key developments for the 1990s are considered. These include base technologies, 3-D user interfaces, virtual realities, multimedia and hypermedia, groupware, and intelligent agents, i.e., computer-based assistants or guides.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Endovascular Treatment of Thoracic Aortic Aneurysms (2003)

Endovascular repair of thoracic aortic aneurysms is a promising modality that may someday replace open surgical repair. While stent grafts have been used with moderate success in small to moderate-sized retrospective series, there have been no completed multicenter clinical trials directed at gaining approval from the U.S. Food and Drug Administration. The available data suggest that morbidity and mortality of the procedure may be lowered with endovascular techniques. Paraplegia occurs, but despite the inability to maintain perfusion of intercostal vessels, the rate is at least as low as that associated with open repair. Similar to the minimally invasive repair of infrarenal aneurysms, the trade-off between the open and endovascular approach rests in the necessity to follow patients closely with after endovascular repair. The long-term durability of available devices is unproved, and serial imaging studies must be followed in order to detect device failure prior to the development of devastating clinical sequelae.
A VM/Containerized Approach for Scaling TinyML Applications (2022)

Although deep neural networks are typically computationally expensive to use, technological advances in both the design of hardware platforms and of neural network architectures, have made it possible to use powerful models on edge devices. To enable widespread adoption of edge based machine learning, we introduce a set of open-source tools that make it easy to deploy, update and monitor machine learning models on a wide variety of edge devices. Our tools bring the concept of containerization to the TinyML world. We propose to package ML and application logic as containers called Runes to deploy onto edge devices. The containerization allows us to target a fragmented Internet-of-Things (IoT) ecosystem by providing a common platform for Runes to run across devices.
ChemInform Abstract: Synthesis of 5‐epi‐7‐Deoxykalafungin and 5‐epi‐7‐O‐Methylkalafungin. (1990)

Abstract The syntheses of the title compounds (Va) and (Vb) are completed making use of the transformation of one tricyclic ring system into another.
Methods of automatic vegetation encroachment detection for high voltage power lines (2020)

Overhead inspections of high voltage power lines are very expensive undertaking. Power lines require systematic inspections to avoid failures and power outages. In each growing season vegetation encroachment is one of the most severe threat. Presently overhead inspections use helicopters and are carried out manually at least once a year. More cost effective systems, using UAV, are being researched. In this paper selected methods from all studied solutions were compared. A cost effective system was proposed using consumer grade UAV with standard camera and deep neural networks for detecting vegetation encroachment.
Intrapericardial β-Adrenergic Blockade with Esmolol Exerts a Potent Antitachycardic Effect Without Depressing Contractility (2000)

Hyperadrenergic states of various etiologies can contribute to tachycardias. Systemic beta-adrenergic blockade suppresses sinus tachycardia but may adversely affect arterial blood pressure and contractility, because the drug gains access to myocardial cells as well as to the sinoatrial node. We examined whether intrapericardial beta-adrenergic blockade with esmolol could suppress tachycardia without reducing contractility as a result of limited drug diffusion, which would be sufficient to penetrate the superficial sinoatrial node but not the deeper myocardial layers. In five anesthetized pigs, we provoked a reflex heart rate increase of 50 beats/min with hemorrhage. The rapidly acting beta-adrenergic blocking agent esmolol (1 mg/kg) was administered intrapericardially using a new percutaneous transatrial access method and a catheter system that can be rapidly and safely introduced. Esmolol equivalently suppressed hemorrhage-induced sinus tachycardia when administered intrapericardially (from 192 to 158 beats/min at 5 min, p < 0.05) or intravenously (from 177 to 151 beats/min at 1 min, p < 0.05). The antitachycardic effect of intrapericardial esmolol was prolonged compared with intravenous esmolol (10 min vs. 3 min, p < 0.05). Intrapericardial esmolol did not affect blood pressure or left ventricular dP/dt max, an index of contractility, whereas intravenous esmolol decreased blood pressure at 1 min for 2 min (p < 0.05) and simultaneously decreased left ventricular dP/dt max at 1 min for < 2 min (p < 0.05). Intrapericardial esmolol suppresses adrenergically induced sinus tachycardia without decreasing contractility or blood pressure. The transatrial approach for intrapericardial delivery of certain 1-adrenergic blocking agents could be employed to control tachycardias in emergency care and surgical settings in patients with impaired cardiac contractility and propensity to hypotension.
Evolutionary trends in intelligent networks (2000)

A number of groups are currently developing technologies aimed at evolving and enhancing the capabilities of intelligent networks. In this article we discuss three of these initiatives: PINT, Parlay, and IN/CORBA interworking. The IETF PINT work addresses how Internet applications can request and enrich telecommunications services. The Parlay consortium is specifying an object-oriented service control API that facilitates the access, control, and configuration of IN services by enterprise IT systems. The OMG's IN/CORBA interworking specification enables CORBA-based systems to interwork with existing IN infrastructure, thereby promoting the adoption of CORBA for the realization of IN functional entities. We address how all three of these technologies could be deployed together in order to provide a basis for a more flexible and open IN architecture. We also identify a number of common trends and potential pitfalls highlighted by current work on the evolution of IN.
A fast marching level set method for monotonically advancing fronts. (1996)

A fast marching level set method is presented for monotonically advancing fronts, which leads to an extremely fast scheme for solving the Eikonal equation. Level set methods are numerical techniques for computing the position of propagating fronts. They rely on an initial value partial differential equation for a propagating level set function and use techniques borrowed from hyperbolic conservation laws. Topological changes, corner and cusp development, and accurate determination of geometric properties such as curvature and normal direction are naturally obtained in this setting. This paper describes a particular case of such methods for interfaces whose speed depends only on local position. The technique works by coupling work on entropy conditions for interface motion, the theory of viscosity solutions for Hamilton-Jacobi equations, and fast adaptive narrow band level set methods. The technique is applicable to a variety of problems, including shape-from-shading problems, lithographic development calculations in microchip manufacturing, and arrival time problems in control theory.
Efficacy of sodium hypochlorite and peracetic acid in sanitizing green coconuts (2009)

Sanitation of green coconut is one of the most important control measures to prevent the contamination of coconut water. This article provides information that shows the adequacy of sanitizing treatments applied by the juice industries.
Role of HA additive in quantum dot solar cell with Co[(bpy)3]2+/3+-based electrolyte (2014)

In a system of TiO<sub>2</sub>/CdS QDSCs with [Co(bpy)<sub>3</sub>]<sup>2+/3+</sup> complexes, back recombination loss between Co<sup>III</sup> and the TiO<sub>2</sub> nanorod surface is significantly alleviated by introducing hexanoic acid (HA) on TiO<sub>2</sub>/CdS electrode surface.
Applications of Fluorous Compounds in Materials Chemistry: 12.1 Basic Principles and Recent Advances in Fluorinated Self‐Assemblies and Colloidal Systems (2004)

This chapter contains sections titled: Introduction Basic Physicochemical Properties Fluorocarbons Fluorinated Surfactants Semifluorinated Alkanes: a Class of Special Amphiphiles Self-Assembly Behavior of F-Amphiphiles Vesicles Tubules and Fibers Bi-dimensional Films Langmuir and Gibbs Monolayers Self-Assembled Monolayers Emulsions and Microemulsions Containing a Fluorocarbon or a Fluorinated Surfactant Fluorocarbon Emulsions and Microemulsions Water-in-CO2 Microemulsions Fluorocarbon Microbubbles Fluorocarbon Polymers Conclusions and Perspectives
The impact of closed-loop intracortical stimulation on neural activity in brain-injured, anesthetized animals (2022)

This study describes the impact on single-unit activity in ipsilesional areas immediately following a cortical infarct and demonstrates that application of ADS is effective in altering this activity.
Stakeholder consultation to facilitate implementation of interventions for prevention and promotion in mental health in Europe: introducing the design of the ICare Stakeholder Survey (2021)

The challenge was to develop a design that allowed flexibility but at the same did not jeopardize the validity of the study. Implications drawn from this survey are not restricted to specific preventive interventions but will provide general information on how online mental illness prevention can be best implemented in various settings.
Electronic control in random access analysers (1988)

Improvements in microchip technology have produced a new breed of computerized laboratory analysers. Modern analysers have both self-acting and self-regulating mechanisms. Automatic self-checking diagnostics allow preventive service and repair. An instrument can be implemented through changes in software. Chemometrics help to check reagent integrity, validate calibration, and quality control. Computer-assisted interpretation is just beginning to be a possibility.