gebhart/patrepeval huggingface dataset:
Traffic-Aware OTN-over-WDM Optimization in 5G Networks (2022)

5G networks are expected to support a diverse set of new applications/services in addition to existing applications/services from previous generations (2G/3G/4G). Optical Transport Networks (OTN) are being deployed as one attractive supporting technology for 5G networks at the transport level, particularly for next generation transport networks featuring large-granule broadband service transmissions. However, adopting and deploying OTNs in 5G networks comes with its own set of challenges. Thus, for carrier networks based on optical paths to become more scalable, dynamic, and manageable, there is a need to account for incoming traffic characteristics. To that end, this work formulates the problem of traffic-aware OTN-over-WDM optimization in the context of 5G. More specifically, it studies the impact of the different 5G traffic types and environments on the cost at both the OTN and WDM layers. Simulation results using different network topologies show the higher cost associated with more demanding traffic types and the variation in aggregate costs for different environments/scenarios. This includes a 2x increase in the aggregate network cost per layer and a 1.2x increase in average network cost per demand per layer and average network cost per demand per demand type between the different topologies. Additionally, results show that the optimization model outperforms a recent previous work by almost a factor of 2.
Fan-Out Packaging of Microdevices Assembled Using Micro-Transfer-Printing (2016)

This paper describes and demonstrates a high-throughput strategy for making fan-out packages for very small, sub-millimeter, devices. First, micro-transfer printing was used to deterministically assemble large arrays of devices, face-up, onto 200 mm wafers. The devices used in this study were 80 um × 40 um chips with a redistribution metal and six contact pads designed to be used as an electrical test vehicle. The printed devices are approximately two microns in thickness. After assembly of the reconfigured wafers, they undergo a standard wafer level redistribution and bumping process. The final fan-out package pitch on the 200 mm wafer is 1.4mm × 1.0mm with six 250 um solder bumps. The fan-out packages were assembled and reflowed onto FR4 test boards specifically designed for this study. The process and interconnect yield will be reported, as well as initial reliability testing results. In summary, we have demonstrated a new strategy for cost effective fan-out packaging of very small devices. This strategy depends on a massively parallel deterministic assembly process capable of delivering very thin devices to the reconfigured package substrate. A key attribute of this approach is that no molding compound is used in the package.
Anisotropic Electric Conductivity in an Aligned DNA Cast Film (1998)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTAnisotropic Electric Conductivity in an Aligned DNA Cast FilmYoshio Okahata, Takuya Kobayashi, Kentaro Tanaka, and Masatsugu ShimomuraView Author Information Department of Biomolecular Engineering Tokyo Institute of Technology Nagatsuda, Midori-ku, Yokohama 226, Japan Research Institute for Electronic Science Hokkaido University Kita-ku, Sapporo 060, Japan Cite this: J. Am. Chem. Soc. 1998, 120, 24, 6165–6166Publication Date (Web):June 5, 1998Publication History Received15 January 1998Published online5 June 1998Published inissue 1 June 1998https://doi.org/10.1021/ja980165wCopyright © 1998 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views1752Altmetric-Citations305LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (36 KB) Get e-AlertscloseSUBJECTS:Electrical conductivity,Electrodes,Genetics,Photonics,Solution chemistry Get e-Alerts
Some kind of beautiful : the grotesque body in contemporary art (2006)

Lipopolysaccharides (LPS) were extracted from cells of Wolinella recta ATCC 33238, W. curva ATCC 33224, W. succinogenes ATCC 29543 and Campylobacter sputorum ssp. sputorum A 3563 by a hot phenol-water method and purified by nuclease treatment and by repeated ultracentrifugation. Chemical compositions of the purified LPS including fatty acid and sugar composition were examined and sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) was performed. All LPS preparations contained a monosaccharide identified as L-glycero-D-mannoheptose, and another heptose isomer identified as D-glycero-D-mannoheptose was a typical constituent of the LPS from all three Wolinella species.
Practical Preparation of Chiral 4-Substituted 2-Oxazolidinones (1992)

Abstract A versatile and practical route to both enantiomers of a wide variety of 4-substituted 2-oxazolidinones from the parent heterocycle is provided by regioselective substitutions via 4-methoxy derivative followed by chromatographic separation of the diastereomers derived from N-2-exo-methoxy-1-apocamphanecarbonylation.
Constant-potential molecular dynamics simulations of molten salt double layers for FLiBe and FLiNaK (2022)

We report the results of constant-potential molecular dynamics simulations of the double layer interface between molten 2LiF-BeF<sub>2</sub> (FLiBe) and 23LiF-6NaF-21KF (FLiNaK) fluoride mixtures and idealized solid electrodes. Employing methods similar to those used in studies of chloride double layers, we compute the structure and differential capacitance of molten fluoride electric double layers as a function of applied voltage. The role of molten salt structure is probed through comparisons between FLiBe and FLiNaK, which serve as models for strong and weak associate-forming salts, respectively. In FLiBe, screening involves changes in Be-F-Be angles and alignment of the oligomers parallel to the electrode, while in FLiNaK, the electric field is screened mainly by rearrangement of individual ions, predominantly the polarizable potassium cation.
Effects of Surfactants on the Preparation of Nanocellulose-PLA Composites (2017)

Thermoplastic composite materials containing wood fibers are gaining increasing interest in the manufacturing industry. One approach is to use nano- or micro-size cellulosic fibrils as additives and to improve the mechanical properties obtainable with only small fibril loadings by exploiting the high aspect ratio and surface area of nanocellulose. In this study, we used four different wood cellulose-based materials in a thermoplastic polylactide (PLA) matrix: cellulose nanofibrils produced from softwood kraft pulp (CNF) and dissolving pulp (CNFSD), enzymatically prepared high-consistency nanocellulose (HefCel) and microcellulose (MC) together with long alkyl chain dispersion-improving agents. We observed increased impact strength with HefCel and MC addition of 5% and increased tensile strength with CNF addition of 3%. The addition of a reactive dispersion agent, epoxy-modified linseed oil, was found to be favorable in combination with HefCel and MC.
Folding simulations and computer redesign of protein A three-helix bundle motifs (1996)

In solution, the B domain of protein A from Staphylococcus aureus (B domain) possesses a three-helix bundle structure. This simple motif has been previously reproduced by Kolinski and Skolnick (Proteins 18: 353-366, 1994) using a reduced representation lattice model of proteins with a statistical interaction scheme. In this paper, an improved version of the potential has been used, and the robustness of this result has been tested by folding from the random state a set of three-helix bundle proteins that are highly homologous to the B domain of protein A. Furthermore, an attempt to redesign the B domain native structure to its topological mirror image fold has been made by multiple mutations of the hydrophobic core and the turn region between helices I and II. A sieve method for scanning a large set of mutations to search for this desired property has been proposed. It has been shown that mutations of native B domain hydrophobic core do not introduce significant changes in the protein motif. Mutations in the turn region were also very conservative; nevertheless, a few mutants acquired the desired topological mirror image motif. A set of all atom models of the most probable mutant was reconstructed from the reduced models and refined using a molecular dynamics algorithm in the presence of water. The packing of all atom structures obtained corroborates the lattice model results. We conclude that the change in the handedness of the turn induced by the mutations, augmented by the repacking of hydrophobic core and the additional burial of the second helix N-cap side chain, are responsible for the predicted preferential adoption of the mirror image structure.
Scalable Growth of High-Quality Polycrystalline MoS2 Monolayers on SiO2 with Tunable Grain Sizes (2014)

We report a scalable growth of monolayer MoS2 films on SiO2 substrates by chemical vapor deposition. As-grown polycrystalline MoS2 films are continuous over the entire substrate surface with a tunable grain size from ∼20 nm up to ∼1 μm. An obvious blue-shift (up to 80 meV) of photoluminescence peaks was observed from a series samples with different grain sizes. Back-gated field effect transistors based on a polycrystalline MoS2 film with a typical grain size of ∼600 nm shows a field mobility of ∼7 cm(2)/(V s) and on/off ratio of ∼10(6), comparable to those achieved from exfoliated MoS2. Our work provides a route toward scaled-up synthesis of high-quality monolayer MoS2 for electronic and optoelectronic devices.
SecA2 functions in the secretion of superoxide dismutase A and in the virulence of Mycobacterium tuberculosis (2003)

Tuberculosis remains a severe worldwide health threat. A thorough understanding of Mycobacterium tuberculosis pathogenesis will facilitate the development of new treatments for tuberculosis. Numerous bacterial pathogens possess specialized protein secretion systems that are dedicated to the export of virulence factors. Mycobacterium tuberculosis is part of a developing group of pathogenic bacteria that share the uncommon property of possessing two secA genes (secA1 and secA2). In mycobacteria, SecA1 is the essential 'housekeeping' SecA protein whereas SecA2 is an accessory secretion factor. Here we demonstrate that SecA2 contributes to the pathogenesis of M. tuberculosis. A deletion of the secA2 gene in M. tuberculosis attenuates the virulence of the organism in mice. By comparing the profile of proteins secreted by wild-type M. tuberculosis and the DeltasecA2 mutant, we identified superoxide dismutase A (SodA) as a protein dependent on SecA2 for secretion. SodA lacks a classical signal sequence for protein export. Our data suggests that SecA2-dependent export is a new type of secretion pathway that is part of a virulence mechanism of M. tuberculosis to elude the oxidative attack of macrophages.
Spectroscopic Identification of Dihydroxycarbene (2008)

Klein, aber fein: Das Abspalten von CO2 aus einfachen α-Ketocarbonsäuren lieferte bisher unbekannte Hydroxycarbene. Die Blitzpyrolyse von Oxalsäure oder ihrem Monomethylester im Hochvakuum machte die Synthese und Charakterisierung von Dihydroxy- (1) bzw. Hydroxymethoxycarben möglich; beide werden durch eine Out-of-Plane-Konjugation vom π-Typ und eine In-Plane-σ-Konjugation stabilisiert (das HOMO von s-trans, s-trans-1 ist gezeigt). Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2001/2008/z802105_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Plasma Endothelin-1 Levels in Patients with Diabetes Mellitus With or Without Vascular Complication (1991)

Plasma endothelin-1 (ET-1) concentrations were measured in 25 patients with non-insulin-dependent diabetes mellitus (11 with angiopathy and 14 without angiopathy) and 21 normal subjects using radioimmunoassay specific to ET-1. Basal plasma immunoreactive (ir) ET-1 levels in diabetic patients with and without angiopathy were 1.73 +/- 0.29 and 1.68 +/- 0.20 pg/ml, respectively. Although high glucose levels may stimulate ET-1 release from vascular endothelial cells in vitro, our data suggest that circulating ET-1 may not be elevated in most diabetic patients with or without angiopathy.
Hazard Analysis of Action Loops for Automated Vehicle Remote Operation (2021)

One way to compensate for the limitations of automated vehicles is to use a remote operator as a fallback controller. Indeed, this has been proposed for ﬂeet management and intermittent vehicle control. However, existing remote operation applications have demonstrated control challenges, such as latency and bandwidth, that inhibit the eﬀectiveness of human operators. Additionally, human factors challenges arising due to the roles of multiple remote operators managing multiple vehicles further complicates these interventions. This paper uses the Systems Theoretic Process Analysis hazard analysis technique to identify system-level issues related to the remote operation of automated vehicles. Human factors challenges are identiﬁed through the lens of two control loops that link remote drivers, dispatchers, and vehicle automation. These control loops reveal familiar challenges, such as situation awareness and mental model mismatches, as well as novel challenges, such as poorly synchronized and misaligned control.
Molecular Responses of Plants to Phosphate Starvation (1996)

Phosphate deficiency is wide spread in the nature. The deficiency results in several morphological and biochemical changes in plants. Some of these changes have been shown to involve altered gene expression. We have isolated two full--length cDNAs (AtPT1 and AtPT2), showing significant amino acid sequence similarity with the high-affinity phosphate transporters of yeast, Neurospora and the mycorrhizal fungi Glomus versiforme , from a phosphate-starved Arabidopsis root library. The transcripts of both genes are highly induced under Pi starvation and they are expressed in roots. Using Arabidopsis cDNAs as probes, we have isolated several tomato root cDNA clones representing the two different genes. The expression characteristics of the tomato isoforms of the putative high affinity phosphate transporter genes will be discussed. The northern blots of RNA isolated from phosphate-deficient and phosphate-sufficient roots of tomato indicated that both genes are strongly induced in response to Pi starvation in roots. Furthermore, by the method of differential display of mRNA, we have cloned and characterized a full-length cDNA representing a Pi starvation induced gene (TPSI1) from tomato. The gene is expressed as a specific response to Pi starvation in roots and leaves. The TPSI1 is an intron-less gene represented by a single copy in the tomato genome. The structure, expression, and functional significance of these genes will be discussed. This research has been supported, in part, by USDA grant 94-37100-0834 to KGR.
A 1.9 GHz-band GaAs direct-quadrature modulator IC with a phase shifter (2003)

A 1.9-GHz-band direct-quadrature modulator IC has been developed for digital cordless telephone use. In the 1.9-GHz high-frequency band, both carrier and image rejections as low as -40 dBc have been obtained with low-power dissipation of 110 mW, corresponding to phase error below 1.1 degrees . A newly developed circuit configuration, which combines a quadrature phase shifter with drivers, make this excellent spectrum efficiency and low-power dissipation possible. This modulator IC is expected to contribute to the realization of enhanced digital mobile communication systems such as digital and cordless digital cellular telephones.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
利多卡因表面麻醉不影响喉电图评估喉的发声：一项前瞻、交叉、随机、双盲的安慰剂-对照研究 (2013)

背景上呼吸道表面麻醉通常推荐用于预测有困难气管的处理。但有研究报道，表面麻醉可能导致气管完全失去控制，其副作用主要是干扰了气管本能保护性反射，但呼吸道本身的运动功能可能受到保护。我们推测如果运动控制受到影响，那么表面麻醉后就会有发声的定量变化。方法24位健康志愿受试者进行了一项前瞻、交叉、随机、双盲研究，每位受试者进行2项发声练习，同时通过光纤鼻内镜检查记录他们的声门表现的数字影像。受试者分别使用3种测试溶液（安慰剂、2％利多卡因、4％利多卡因）漱口，然后重复进行发声练习和鼻内镜检查。通过MB—Ruler测量声带之间的夹角，使用喉动图SpeechStudio软件分析发音参数。结果在对照组和实验组之间音质有显著性差异（P=0．014），其他在安慰剂组和利多卡因组之间没有不同。结论尽管含漱局麻药液会影响喉发声，但研究发现局部麻醉药对受试者不产生药理学作用。
Heterojunction of nano-poly (O-toluidine) on silicon nanowires is investigated as a candidate heterojunction diode (2014)

The organic nanostructured conducting polymer Poly (O-toluidine)/ Silicon nanowires (NPOT/SiNWs) heterojunction is investigated as a candidate heterojunction diode. For this purpose, NPOT/SiNWs heterojunction was fabricated through low cost and simple techniques. SiNWs were fabricated using improved metal-assisted electroless etching of Si substrates. NPOT thin film was chemically fabricated via in situ polymerization method. The morphology of SiNWs before and after deposition of NPOT was confirmed by scanning electron microscope (SEM). I-V measurements of the device were made at room temperature under dark conditions.
Exploration of two-dimensional bio-functionalized phosphorene nanosheets (black phosphorous) for label free haptoglobin electro-immunosensing applications (2018)

We report on the development of an antibody-functionalized interface based on electrochemically active liquid-exfoliated two-dimensional phosphorene (Ph) nanosheets-also known as black phosphorous nanosheets-for the label-free electrochemical immunosensing of a haptoglobin (Hp) biomarker, a clinical marker of severe inflammation. The electrodeposition has been achieved over the screen-printed electrode (SPE) using liquid-assisted ultrasonically exfoliated black phosphorus nanosheets. Subsequently, Ph-SPEs bioconjugated with Hp antibodies (Ab), using electrostatic interactions via a poly-L-lysine linker for biointerface development. Electrochemical analysis demonstrates that the Ab-modified Ph-SPEs (Ab@Ph-SPE) exhibit enhanced electroconducting behavior as compared to the pristine electrodes. This Ab-functionalized phosphorene-based electrochemical immunosensor platform has demonstrated remarkable sensitivity and specificity, having a dynamic linear response range from 0.01-10 mg ml<sup>-1</sup> for Hp in standard and serum samples with a low detection limit (∼0.011 mg ml<sup>-1</sup>) using the label-free electrochemical technique. The sensor electrodes were also studied with other closely relative interferents to investigate cross reactivity and specificity. This strategy opens up avenues to POC (point-of-care) and on-farm livestock disease monitoring technologies for multiplexed diagnosis in complex biological samples such as serum. The technique is simple in fabrication and provides an analytical response in less than 60 s.
Einfluss eines gentechnisch veränderten, Auxin produzierenden Rhizobienstammes auf die bakterielle Bodengemeinschaft (2008)

At present, legumes cover one third of the total protein intake of the human diet. Therefore any improvement of forage and grain legume yields achieved without using potentially harmful chemical fertilizers are of extreme importance, in particular to the developing countries. One promising approach is the inoculation with a genetically modified Rhizobium strain releasing the plant hormone indole-3-acetic acid (IAA) to the rhizosphere of their host plant. For this purpose I used Rhizobium leguminosarum bv. viciae VF39, which was modified by inserting the iaaM (tryptophane monooxygenase) and tms2 (indole-3-acetamide hydrolase) genes for IAA-synthesis into two separate plasmids pRD20 and pBBRIAA, each derived from the same origin. The expression of these two genes in pRD20 is under control of the strong constitutive cat promotor, whereas in pBBRIAA the rolA promotor is stationary-phase and acid inducible. Within the framework of this thesis I analysed the stability and spreading of the plasmids from the genetically modified rhizobia to the present soil bacteria with a cultivation independent detection system. Simultaneously I analysed, whether the inoculation with the genetically modified Rhizobium strain had any impact on the composition and diversity of the bacterial community in the rhizosphere and rhizoplane of Pisum sativum by DGGE analysis and GC-MS. I could investigate a horizontal gene transfer of the used plasmids to the majority of the tested soil bacteria (gram - and gram +). The expression of the eGFP I used to detect the transferred plasmid in the recipient cells was disturbed by metabolic inactivity and the attachment of the bacteria to fluorescent soil particles. Therefore it was not possible to transfer the cultivation independent detection system, developed for aquatic systems, to the soil system. The investigation of an effect of the genetically modified rhizobia indicated that time alone is the core issue that affected the diversity and activity of the soil bacteria. There was no influence of the genetically modified rhizobia strains on the amount of IAA in the rhizosphere of the plants. Finally, no significant effect of genetically modified rhizobia, producing high amounts of IAA, could be observed on the composition and diversity of the present and active part of the soil bacteria.
Virtual restoration of fragmented glass plate photographs (2004)

In this paper we address the problem of restoration of fragmented glass plate photographs. We propose an algorithm based on the roto-translation of the fragments. A preprocessing adjustment in the contour combined with final interpolation is necessary to avoid artifacts.
The synthesis and study of simple glyprolines (2016)

We validated the structure and performed synthesis of eight new peptides that are analogues of proglyprol, with the common formula of Pro(X)-A-Pro(Y). Here we present data on the molecular ligand-receptor activity of these peptide compounds; in particular, we present data on their ability to compete with the tripepetide Pro-Gly-Pro for specific binding sites on the plasma membranes of brain cells. The experiments were performed using a wide range of peptide concentrations, including low and ultralow, down to 10–12 mol/L. It has been shown that the peptides with substitution of the second amino acid and/or containing Ala on the C-terminus of the peptide blocked binding of tritium-labeled Pro-Gly-Pro. Regardless of the structure of the second amino acid in the composition of the modified peptide, 5-oxo-Pro-analogues induced a concentration-dependent increase in the number of binding sites of the radioactive ligand. Elongation of the peptide sequence due to addition of Ala to the C-terminus of the peptide probably increases the affinity of the analogues to the low-affinity binding sites on plasma membranes of brain cells. Taking these data into account, it is possible to consider the studied candidate peptides, i.e., synthetic modifications of the simplest glyproline, as biologically active synthetic molecules.
Fixation of Osteochondritis Dissecans Lesions Using Poly(l-lactic Acid)/ Poly(glycolic Acid) Copolymer Bioabsorbable Screws (2004)

In general, the 2.5-mm-diameter LactoSorb copolymer screws provided adequate stability for healing of osteochondritis dissecans lesions and degraded without an inflammatory response by the body.