gebhart/patrepeval huggingface dataset:
Effect of a Lens Protein in Low-Temperature Culture of Novel Immortalized Human Lens Epithelial Cells (iHLEC-NY2) (2020)

The prevalence of nuclear cataracts was observed to be significantly higher among residents of tropical and subtropical regions compared to those of temperate and subarctic regions. We hypothesized that elevated environmental temperatures may pose a risk of nuclear cataract development. The results of our in silico simulation revealed that in temperate and tropical regions, the human lens temperature ranges from 35.0 °C to 37.5 °C depending on the environmental temperature. The medium temperature changes during the replacement regularly in the cell culture experiment were carefully monitored using a sensor connected to a thermometer and showed a decrease of 1.9 °C, 3.0 °C, 1.7 °C, and 0.1 °C, after 5 min when setting the temperature of the heat plate device at 35.0 °C, 37.5 °C, 40.0 °C, and 42.5 °C, respectively. In the newly created immortalized human lens epithelial cell line clone NY2 (iHLEC-NY2), the amounts of RNA synthesis of αA crystallin, protein expression, and amyloid β (Aβ)1-40 secreted into the medium were increased at the culture temperature of 37.5 °C compared to 35.0 °C. In short-term culture experiments, the secretion of Aβ1-40 observed in cataracts was increased at 37.5 °C compared to 35.0 °C, suggesting that the long-term exposure to a high-temperature environment may increase the risk of cataracts.
First report of leaf blight of Chlorophytum borivilianum caused by Colletotrichum capsici in northern India (2006)

‘Safed musli’ (‘moosli’) (Chlorophytum borivilianum) is a commercially important medicinal plant in India. Cultivation of this crop in Lucknow, Pantnagar and adjoining areas in northern India was severely affected by a leaf blight disease in 2003 and 2004. Initial symptoms were the appearance of minute, pin-head, circular, reddish-brown lesions on the leaves, which form longitudinal streaks along the midrib, veins and margin of the infected leaves. Severely affected leaves dry prematurely and plants fail to produce healthy fingers (tubers) used for medicinal purposes. The disease occurred in August and September, after the onset of the rainy season, and caused losses of up to 30% in severely affected fields. Isolations from the young and mature necrotic lesions on potato dextrose agar (PDA) invariably yielded a Colletotrichum species. The fungus initially produced white to grey mycelial growth which became reddish brown due to copious sporulation after 5–7 days. Acervuli were numerous, globose to saucer shape with large number of dark brown setae 96–124 µm long. Conidiophores were short, simple and hyaline. Conidia were aseptate, fusiform, sickle-shape and single celled. Those from host material were 10–15 (13) × 3–4 (3) µm and 10–21 (14) × 3–5 (4) µm after 7–10 days’ growth on PDA. Based on these morphological features, the fungus was identified as Colletotrichum capsici. Isolates were morphologically identical to C. capsici isolates infecting Ocimum basilicum (Alam et al., 1981). To prove pathogenicity, 45-day-old healthy plants, bearing five to six leaves, were sprayed with C. capsici isolates from Lucknow and Pantnagar regions, in aqueous suspensions of 1·5 × 106 conidia mL−1. Symptoms identical to those found occurring naturally were observed 3–5 days after inoculation. After 7–12 days the original lesions had spread lengthwise and often coalesced to form long, necrotic streaks, producing typical leaf blight symptoms. The inoculated plants died prematurely. Control plants sprayed only with water remained healthy. Colletotrichum capsici was reisolated from the inoculated plants. This is the first record of C. capsici on ‘safed musli’ from India. Colletotrichum chlorophytumi has been recorded on Chlorophytum spp. growing in pots in various gardens in Allahabad (Sudhir Chandra Tandon, 1965). This species has slightly longer and broader conidia, and infections resulted in leaf spots that, at maturity, had three distinct zones of colour, a feature not seen with C. capsici on C. borivilianum.
Potencjał rekreacyjny lasów podmiejskich Rzeszowa wobec zapotrzebowania na wypoczynek w lasach wśród mieszkańców województwa podkarpackiego (2016)

The objective of the study was to determine the size of interest in spending leisure time in forests among the residents of the Podkarpackie Province (south−eastern Poland) and to examine recreational potential of Rzeszów suburban forests. At first, basing on surveys, the demand for leisure in forests among the adult residents of the Podkarpackie Province was assessed. The survey was conducted on the random group of 439 people. Then, the recreational potential of the suburban forests of Rzeszów was assessed using own method. Almost 90% of respondents declared that they spend leisure time in forests. Most of the them rest in forests several times a year (54%), while only 9% respondents does it several times a week. The largest group among people spending their free time in forests is willing to travel up to 20 km to get to a forest. Forests suitable for recreational use cover nearly 56% of the analysed area, Among them 29% are tree stands of high or very high usability. The decrease in usability for recreational purposes predominantly results from the large share of wet habitats and dense understory. The recreational capacity calculated for Rzeszów suburban forests located within 20 km of city administrative limits amount to 1.79 man−hour/ha/day. The presented results indicate that every week 435,000 people may stay in the Podkarpackie Province forests, while approximately 43,000 – in Rzeszów suburban forests. The paper shows that there is a huge interest in spending leisure time in forests among the residents of the Podkarpackie Province, while the calculated recreational potential of Rzeszów suburban forests may be exceeded. Therefore a real risk exists that the forest environment will be damaged, moreover Rzeszów suburban forests are still poorly equipped with recreational facilities. A type of activity that counteracts this disturbing phenomenon is adequate management of recreational traffic and its balanced distribution over the areas that are naturally resistant to damages. It is also necessary to limit recreational utilisation of the forests where the calculated recreational capacity equals 0. Moreover, one should strive to boost recreational capacity of forests by their proper management.
Synthesis and Use in Asymmetric Hydrogenations of Solely Planar Chiral 1,2-Disubstituted and 1,2,3-Trisubstituted Ferrocenyl Diphosphines:  A Comparative Study (2007)

A total of 12 enantiopure 1,2-disubstituted and 1,2,3-trisubstituted ferrocenyl diphosphines [1-Ph2P-2-R2PCH2-3-R‘-Fc, R = Cy, t-Bu, 3,5-(CH3)2C6H3), R‘ = H, CH3, Ph, 3,5-(CH3)2C6H3)] have been synthesized, characterized, and tested in asymmetric rhodium- and ruthenium-catalyzed hydrogenations of four alkenes and two ketones. The performance of these ferrocene derivatives in catalytic hydrogenations was compared to those of catalysts based on Josiphos, PPF-t-Bu2, and Xyliphos [1-Ph2P-2-R2P(CH3)CH-Fc, R = Cy, t-Bu, 3,5-(CH3)2C6H3)]. Dichloro palladium(II) complexes of Xyliphos and its analogues lacking the stereogenic center were synthesized as model compounds, and their molecular structures were studied in solution and, for four complexes, in the solid state. In hydrogenation reactions the replacement of Xyliphos as the catalyst ligand with its analogues lacking the stereogenic center leads to changes in product configurations or significant increases or decreases in ee values.
Giant Polycyclic Aromatic Hydrocarbons (1998)

A new approach for the synthesis of extremely large PAHs in high yield is the oxidative cyclodehydrogenation of suitable oligophenylenes under Kovacic conditions. The synthesis of oligophenylene precursors and their cyclodehydrogenation (figure) are presented, and the supramolecular structures observed for large PAHs are discussed.
Sur l'équilibre liquide‐vapeur à 25° de systèmes ternaires composés d'un nitrate, d'acide nitrique et d'eau (1962)

Abstract Nous avons déterminé la composition et la tension de la vapeur émise, à 25°, par des mélanges d'acide nitrique et d'eau de 50 à 60% HNO 3 contenant des nitrates alcalins et alcalino‐terreux.
Plant Enzyme Structure. Explaining Substrate Specificity and the Evolution of Function (2001)

Progress in defining the three-dimensional (3D) structures of plant enzymes has been generally slow, but in the last 5 years momentum has picked up considerably (Fig.[1][1]). By the beginning of 2000 about 140 individual plant protein structures were known, of which 37 related to individual plant
What???s New in Pulmonary Function Testing? (2006)

In Brief In 2005, the American Thoracic Society and the European Respiratory Society published a set of unified, combined standards for the measurement and interpretation of the most commonly used pulmonary function tests: spirometry, diffusing capacity, and lung volumes. The standards also include a chapter on operational issues for pulmonary laboratories and on the interpretation of lung function tests. This article briefly describes the process of developing the standards, provides a few highlights from the standards, and gives information on how you can access them. This article provides a description of the process of developing the new American Thoracic Society/European Respiratory Society pulmonary function testing guidelines, a brief summary of the standards, and information on how you can access them.
Northwest Territories and Nunavut Snow Characteristics from a Subarctic Traverse: Implications for Passive Microwave Remote Sensing (2008)

Abstract During April 2007, a coordinated series of snow measurements was made across the Northwest Territories and Nunavut, Canada, during a snowmobile traverse from Fairbanks, Alaska, to Baker Lake, Nunavut. The purpose of the measurements was to document the general nature of the snowpack across this region for the evaluation of satellite- and model-derived estimates of snow water equivalent (SWE). Although detailed, local snow measurements have been made as part of ongoing studies at tundra field sites (e.g., Daring Lake and Trail Valley Creek in the Northwest Territories; Toolik Lake and the Kuparak River basin in Alaska), systematic measurements at the regional scale have not been previously collected across this region of northern Canada. The snow cover consisted of depth hoar and wind slab with small and ephemeral fractions of new, recent, and icy snow. The snow was shallow (&amp;lt;40 cm deep), usually with fewer than six layers. Where snow was deposited on lake and river ice, it was shallower, denser, and more metamorphosed than where it was deposited on tundra. Although highly variable locally, no longitudinal gradients in snow distribution, magnitude, or structure were detected. This regional homogeneity allowed us to identify that the observed spatial variability in passive microwave brightness temperatures was related to subgrid fractional lake cover. Correlation analysis between lake fraction and Advanced Microwave Scanning Radiometer for Earth Observing System (AMSR-E) brightness temperature showed frequency dependent, seasonally evolving relationships consistent with lake ice drivers. Simulations of lake ice thickness and snow depth on lake ice produced from the Canadian Lake Ice Model (CLIMo) indicated that at low frequencies (6.9, 10.7 GHz), correlations with lake fraction were consistent through the winter season, whereas at higher frequencies (18.7, 36.5 GHz), the strength and direction of the correlations evolved consistently with the penetration depth as the influence of the subice water was replaced by emissions from the ice and snowpack. A regional rain-on-snow event created a surface ice lens that was detectable using the AMSR-E 36.5-GHz polarization gradient due to a strong response at the horizontal polarization. The appropriate polarization for remote sensing of the tundra snowpack depends on the application: horizontal measurements are suitable for ice lens detection; vertically polarized measurements are appropriate for deriving SWE estimates.
Time domain reflection technique for microwave non destructive testing of Steel Fiber Reinforced Concrete (2010)

Abstract—Preliminary results of a time domain reflection approach for the non-destructive testing of Steel Fiber Reinforced Concrete (SFRC) are presented in this paper. An open-ended epoxy-filled waveguide and a reflector plate located behind the material sample are used to measure its effective permittivity. An electromagnetic model based on the Maxwell-Garnett approach for dielectric mixtures is used to relate the effective permittivity of SFRC to its fiber dosage. Agreement with the expected dosage figures is obtained. Time domain results are compared with frequency domain results obtained in previous experiments. Conclusions regarding the suitability of this method are derived. I.
Tolerance and Autoimmunity to Neoantigen Expressed in Retina (2003)

Conference Abstract| April 01 2003 Tolerance and Autoimmunity to Neoantigen Expressed in Retina Janson C H Leung; Janson C H Leung 1 Nuffield Department of Medicine, University of Oxford, UK Search for other works by this author on: This Site PubMed Google Scholar Helen Ferry; Helen Ferry 1 Nuffield Department of Medicine, University of Oxford, UK Search for other works by this author on: This Site PubMed Google Scholar Hui Rong Jiang; Hui Rong Jiang 2 Department of Ophthalmology, University of Aberdeen, UK Search for other works by this author on: This Site PubMed Google Scholar Tanya L Crockford; Tanya L Crockford 1 Nuffield Department of Medicine, University of Oxford, UK Search for other works by this author on: This Site PubMed Google Scholar John V Forrester; John V Forrester 2 Department of Ophthalmology, University of Aberdeen, UK Search for other works by this author on: This Site PubMed Google Scholar John M Nickerson; John M Nickerson 3 Department of Ophthalmology, Emory University, Atlanta, GA, USA Search for other works by this author on: This Site PubMed Google Scholar Richard J Cornall Richard J Cornall 1 Nuffield Department of Medicine, University of Oxford, UK Search for other works by this author on: This Site PubMed Google Scholar Clin Sci (Lond) (2003) 104 (s49): 49P. https://doi.org/10.1042/cs104049P Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Cite Icon Cite Get Permissions Citation Janson C H Leung, Helen Ferry, Hui Rong Jiang, Tanya L Crockford, John V Forrester, John M Nickerson, Richard J Cornall; Tolerance and Autoimmunity to Neoantigen Expressed in Retina. Clin Sci (Lond) 1 April 2003; 104 (s49): 49P. doi: https://doi.org/10.1042/cs104049P Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsClinical Science Search Advanced Search This content is only available as a PDF. © 2003 The Biochemical Society and the Medical Research Society2003 Article PDF first page preview Close Modal You do not currently have access to this content.
A Hierarchical Primitive Lists Structure for Tile-Based Rendering (2009)

Tile-based rendering has been widely used in resource-limited graphic processing environments, e.g., for hand-held devices. Since large primitives may cover a significant number of tiles, they need to be recorded in the primitive lists of all related tiles. We propose a hierarchical primitive lists structure, which also copes with misaligned and non-square primitive problems, to minimize the primitive recording.Intended advantages include: reduced storage pressure, list building time, primitive retrieval counts for subsequent rendering, primitive data accesses (from external memory)during rendering, and possibly enhanced data locality/resource utilization if layer-based rendering is exploited. Based on this structure, we propose a primitive-hierarchy fitting (hardware)algorithm which, for a given primitive of any size and shape,determines a best way of storing it in the structure. Experimental results on Doom3 and Quake4 show 10% to 33% storage reduction with our full capability, compared with using square hierarchies only.
4.2: Invited Paper : Development of High Mobility Zinc Oxynitride Thin Film Transistors (2013)

Abstract Possible mechanisms to achieve high mobility in zinc oxynitride (ZnON) have been investigated by comparison with other thin film semiconductors. Integrated processes to fabricate ZnON TFTs have been developed. Issues and challenges encountered at current stage will be discussed.
Les cellules NK : biologie, modes de régulation et intérêt clinique (1998)

Les cellules Natural Killer (NK), decouvertes il y a plus de vingt ans, ont ete longtemps considerees comme uniquement cytotoxiques. La cytotoxicite naturelle des cellules NK s'exerce, par une voie differente des lymphocytes T cytotoxiques (CTL), car elle n'est pas restreinte par la presentation antigenique par le complexe majeur d'histocompatibilite de classe 1 (CMH-1) et peut s'exercer sans immunisation prealable [1]. Cependant, les etudes recentes ont modifie les donnees initiales concernant les cellules NK. En effet, 1) ces cellules sont aussi capables de secreter un ensemble de cytokines, de chemokines et de facteurs de croissance impliques dans la reaction inflammatoire et dans l'hematopoiese ; 2) leur activite (cytotoxique et secretoire) est regulee par la reconnaissance ou non de l'expression des molecules du CMH-1 exprimees a la surface des cellules cibles ; 3) finalement, si la possibilite de lyse en l'absence d'immunisation prealable se verifie pour la cytotoxicite dite naturelle, la cytotoxicite dependante de la presence d'anticorps (antibody-dependant cell cytotoxicity ou ADCC) n'est fonctionnelle qu'apres induction de la reponse immunitaire specifique et synthese d'immunoglobulines (Ig). L'activite des cellules NK est en permanence regulee par des recepteurs membranaires, capables d'inhiber ou d'activer leurs fonctions. Cet equilibre delicat entre des signaux d'activation ou d'inhibition permet aux cellules NK de lyser de preference les cellules infectees par un virus ainsi que les cellules tumorales, en epargnant les cellules normales du soi. L'analyse de ces recepteurs membranaires et l'analogie de certains d'entre eux avec les recepteurs activateurs des lymphocytes T et B ont enrichi nos connaissances sur les mecanismes moleculaires impliques dans la fonction de ces cellules. L'ensemble de ces nouvelles donnees et l'interet clinique de l'utilisation des cellules NK a des fins therapeutiques anti-tumorales (particulierement en hematologie) et anti-infectieuses justifient qu'une revue generale leur soit consacree.
Analyzing Exascale Memory Architectures Using the SST Toolkit. (2019)

Abstract not provided.
The effect of internal oscillators on the acoustic response of a submerged shell (1997)

The effect of a large number (≈1000) of internal mechanical oscillators on the acoustic backscattering cross section of a submerged ribbed shell has been experimentally investigated. A comparison of the backscattering cross section of the shell with oscillators to that of a simple ribbed shell with no oscillators shows a number of significant effects arising from the internal structure and overall a significantly increased average scattering strength. These results are presented and several physical mechanisms which can account for the salient aspects of the observations are discussed.
Synthesis of polyisocyanide compounds via .alpha.-metalation reactions (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of polyisocyanide compounds via .alpha.-metalation reactionsMichael G. Hill, Matthew C. Comstock, and Kent R. MannCite this: J. Org. Chem. 1990, 55, 16, 4950–4951Publication Date (Print):August 1, 1990Publication History Published online1 May 2002Published inissue 1 August 1990https://pubs.acs.org/doi/10.1021/jo00303a036https://doi.org/10.1021/jo00303a036research-articleACS PublicationsRequest reuse permissionsArticle Views143Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Gravity-driven motion of a swarm of bubbles in a vertical pipe (2015)

In this work, Direct Numerical Simulations of gravity-driven motion of a swarm of bubbles in a vertical pipe are presented. These simulations were carried out in the contex of a multiple marker level-set methodology, which is integrated in a finite volume framework on collocated unstructured grids. Each fluid particle is described by a separate level-set function, thus, different interfaces can be solved at the same control volume, avoiding the coalescence of the bubbles. Present simulations have been performed in a periodic vertical domain divided in 21E6 hexahedral control volumes, distributed in 2048 CPUs. Collective and individual behaviour of the bubbles are characterized and compared with previous results reported in the literature for other flow configurations.
The safety catch principle in solid phase peptide synthesis (1971)

N-Protected amino-acid active esters react readily with polystyrenesulphonamide yielding, after deprotection, the poly(aminoacylsulphonamides): these polymers are suitable for solid phase peptide synthesis, the completed peptide being cleaved from the resin by methylation and hydrolysis or aminolysis.
Synthesis and Ionic Conductivity of Supramolecular Layered Silicate Hybrids of Phosphotungstates and Poly(ethylene glycol) Dicarboxylates (1999)

The structure-directing roles of phosphotungstic acid and polyethyleneglycol dicarboxylic acid in leading to supramolecular ionic lamellar structures have been demonstrated by the sol−gel acid/base adduct formation between 3-aminopropyl triethyoxysilane and the acids. The prepared inorganic/organic hybrid phyllosilicates exhibited conductivities of up to 10-5 S/cm at 177 °C which are strongly structure-sensitive (variation by 4 orders of magnitude depending on whether a layered or an amorphous structure is realized).