gebhart/patrepeval huggingface dataset:
Transient Analysis of Anodic Dissolution Mechanism of Iron in Sulfuric Acid Solution with Channel Flow Double Electrode (1993)

The anodic dissolution mechanism of iron has been investigated using a channel flow double electrode (CFDE) system. The transient current in iron dissolution is separated into partial currents for dissolution of ions and formation of the adsorbed species, using FFT analysis with a dynamic collection number N(ω) of the electrode system. The dissolution of ferrous ions follows the formation of the adsorbed intermediate in the active dissolution potential region. The experimental results support that the anodic dissolution mechanism of iorn in sulfuric acid solution contains two adsorbed species. In the frequency domain, the efficiencies of the formation of adsorbed intermediate on the iron surface Φf(ω) and of the dissolution of ferrous ions Φdiss(ω) are obtained from FFT analysis of current transient curves. The amplitude of Φdiss(ω) decreases and that of Φf(ω) increases with the frequency. The numerical simulations for iron dissolution based on the reaction model involving two adsorbed species have been performed and the results have agreed well with that of the experiment in time and frequency domains.
Citrate pharmacokinetics and metabolism in cirrhotic and noncirrhotic critically ill patients (2003)

This first systematic study on citrate pharmacokinetics and metabolism in critically ill patients confirms a major role of hepatic citrate metabolism by demonstrating reduced citrate clearance in cirrhotic patients. Pharmacokinetic data could provide a basis for the clinical use of citrate anticoagulation in critically ill patients. Provided dose adaptation and monitoring of ionized calcium, citrate anticoagulation seems feasible even in patients with decompensated cirrhosis. Metabolic consequences of citrate infusion were not different between groups in this study but may be more pronounced in prolonged infusion.
Radiation Effects in Ceramics: Ceramics dislike strain, so they react to adapt (2012)

International audience
Refactoring Aspects into Java Code (2007)

One of the principles of the agile development methodology is to "welcome changing requirements even late in development". Refactoring is a major technique used to cope with changes. It enables to reorganize code while preserving the external behavior. Several refactorings can be performed automatically. Aspect oriented programming (AOP) is a powerful technology that greatly improves programmer's ability to quickly introduce changes to a software system. AOP enables easily modifying behavior of numerous locations in the system code or adding new behavior. AOP is perceived by some people not to be mature enough; hence they avoid using it in production software. We have developed ACME, a prototype tool that implements a refactoring process for aspects. ACME enables a developer to convert AspectJ code to pure Java code according to conversion patterns. The available patterns are creating a singleton class from an aspect and merging aspects into existing classes. The tool creates modular and readable object-oriented code. This paper presents ACME functionality using example transformations and discusses the tool's applicability and decisions made during its design.
In vivo pH mapping of injured lungs using hyperpolarized [1‐13C]pyruvate (2016)

It is demonstrated that hyperpolarized <sup>13</sup> C-bicarbonate can be efficiently produced from the base-catalyzed decarboxylation of pyruvate. This method is used to obtain the first regional pH image of the lungs and heart of an animal. Magn Reson Med 78:1121-1130, 2017. © 2016 International Society for Magnetic Resonance in Medicine.
Dependency of Optical Scintillation Frequency on Wind Speed (1965)

An analysis of normalized power spectra of optical scintillation for horizontal paths near the ground showed that the frequency of maximum power increased linearly with wind speed component normal to an optical path. Corroborative results were obtained from separate experiments with different optical path lengths and heights.
Etude de la variabilité du Peanut Clump Virus (1993)

Le virus du rabougrissement de l'arachide (PCV) est un furovirus, virus en bâtonnets à deux composants. A l'origine de l'étude étiologique du PCV, ce virus était associé au symptôme du rabougrissement de la plante mais depuis 1986 il a pu être associé à des symptômes tout à fait différents (points jaunes, marbrures, taches annulaires et arabesques). 41 isolats de PCV testés en provenance du Sénégal, Burkina Faso, Niger et Inde se répartissent en 5 groupes symptomatologiques différents qui ont été confirmés par une étude sérologique
Pharmacological Blockade of NF-kB Targets Both Imatinib-Sensitive or -Resistant Chronic Myeloid Leukemia Cells for Cell Death. (2006)

Abstract The Bcr-Abl inhibitor imatinib is now the first line therapy for all newly diagnosed CML patients in chronic phase. Nevertheless resistance to the drug emerges as CML progresses to an acute deadly phase. Additional cellular targets should thus be identified to develop alternative therapeutic strategies. The transcription factor NF-kB is a pro-survival factor, found abnormally active in numerous hematologic malignancies. In the present study we show that the constitutive and abnormal activation of NF-kB in Bcr-Abl transformed BaF3 cells and in the LAMA84 CML line could be downregulated after inhibition of Bcr-Abl. Pharmacological blockade of NF-kB by the IKK2 inhibitor AS602868 (Serono International S.A.) prevented proliferation of BaF3/Bcr-Abl, LAMA84 and primary CML cells. Importantly, AS602868 led to apoptosis of an imatinib resistant variant of LAMA84 and of BaF3 clones expressing mutated form of Bcr-Abl derived from imatinib resistant patients. Moreover, NF-kB inhibition affected proliferation and hematopoietic colony formation of primary imatinib resistant CML cells. Finally, the IKK2 inhibitor prolonged survival of mice intravenously injected with the imatinib resistant clone LAMA84-r. Our data strongly suggest that NF-kB mediates important survival functions in CML cells for bcr-abl and that targeting NF-kB with the IKK2 inhibitor AS602868 may represent a new promising therapeutic strategy for CML treatment.
A 20Gbps 1.2GHz full-duplex integrated AFE in 28nm CMOS for copper access (2017)

A 28nm CMOS 1.2GHz full-duplex analog front end (AFE) is presented. The AFE can deliver 20Gbps of aggregate service across 50m of RG6 coax. The on-chip line driver, powered from a 7.2V supply and using core transistors, delivers 5.9Vptp differential to the line through the hybrid. A tunable capacitive hybrid circuit for full duplex operation is proposed for low noise performance and allows channel matching. A cancellation of 23.1dB on average is achieved across the full band. A 3-stage receiver with input over-voltage protection is capable of driving 50Ω differential loads. The chip occupies 0.28mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> of active area and consumes 1.53W.
Development of the Ground Segment Communication System for the EIRSAT-1 CubeSat (2021)

The 16th International Conference on Space Operations, Cape Town, South Africa, 3-5 May 2021
Cryofiltration in the Treatment of Cryoglobulinemia and HLA Antibody‐Incompatible Transplantation (2011)

Cryofiltration is a technique in which plasma is separated from blood and chilled, leading to the formation of "cryogel", a composite of heparin, fibronectin, fibrinogen, immunoglobulins, and other proteins. This is retained by further filtration and plasma is returned to the patient. There may be a role for cryofiltration in the treatment of cryoglobulinemia or where the application of other forms of plasmapheresis or immunoadsorption is limited. Five patients received six courses of cryofiltration. Two patients had cryoglobulinemia and three were treated before HLA antibody-incompatible renal transplantation. The treatment was associated with few adverse effects, and it was possible to treat up to 120 mL/kg plasma per session. There was a good clinical response in four patients. One patient was switched back to double filtration plasmapheresis (DFPP) because cryofiltration seemed to remove HLA antibodies less effectively, but the other two transplants have excellent function. In the cryoglobulinemia patients there was excellent clearance of cryoglobulins during each treatment (mean decrease of 78.2 (SD 14.1)% per treatment). Compared with DFPP, fewer immunoglobulins were removed and the mean percentage reductions in immunoglobulin G per treatment were 36.0 (4.0)% for cryoglobulinemia and 59.2 (2.5)% for DFPP (P < 0.01), with respective mean plasma volumes of 64.2 (10.3) and 71.1 (6.8) mL/kg treated. Cryofiltration offers a treatment choice in patients with cryoglobulinemia and in those who may not be able to tolerate high-volume DFPP. The technique used in the patients described here was less effective than DFPP; however, use of an alternative fractionator and treatment of higher plasma volumes may enhance the efficiency of cryofiltration.
A realtime vehicle tracking system (2005)

This paper describes a method of object tracking that can be applied to real-time scene analysis applications. The proposed method combines spectral blob analysis combined with zone-based detection. Objects are identified by their color signatures and then tracked in the camera's field of view. The field of view is mapped into zones that represent logical separations of the scene, such as lanes of traffic. The method was implemented with the CMUcam2, which is a low cost sensor used in the experiments. The results demonstrate that the method developed can track multiple color objects at rates as high as 15 frames per second. The system also stores a behavioral history of the object motion within the scene, allows for the detection of occurrences such as lane changes.
Chemical Pressure and Hydrogen Insertion Effects in CeNiIn. (2004)

Abstract For Abstract see ChemInform Abstract in Full Text.
Genetics of the phage growth limitation (Pgl) system of Streptomyces coelicolor A3(2) (2002)

The phage growth limitation (Pgl) system, encoded by Streptomyces coelicolor A3(2), confers protection against the temperate bacteriophage phiC31 and its homoimmune relatives. The Pgl phenotype is characterized by the ability of Pgl+ hosts to support a phage burst on initial infection but subsequent cycles are severely attenuated. Previously, two adjacent genes pglY and pglZ were shown to be required for Pgl. It had been shown by Southern blotting that Streptomyces lividans, a close relative of S. coelicolor and naturally Pgl-, does not contain homologues of pglYZ and that introduction of pglYZ into S. lividans is not sufficient to confer a Pgl+ phenotype. Moreover, the mechanism of the Pgl+<--> Pgl- phase variation associated with this phenotype is also not understood. Here we describe two novel genes, pglW and pglX, that were shown to be part of this system by complementation of Pgl- mutants and by insertional mutagenesis. pglW encodes a 169 kDa protein that includes putative motifs for both serine/threonine protein kinase activity and DNA binding. pglX encodes a 136 kDa protein with putative adenine-specific DNA methyltransferase activity. pglW and pglX have overlapping stop-start codons suggesting transcriptional and translational coupling. S1 mapping of transcripts initiating up-stream of pglW indicated that, like pglYZ, pglWX is expressed in uninfected cultures. A homologue of pglX with 76% amino acid identity was identified in S. coelicolor, and insertional mutagenesis indicated that this gene was not required for the Pgl+ phenotype. Southern blots indicated that S. lividans does not contain homologues of pglW or pglX. A plasmid encoding pglWXYZ was able to confer the Pgl+ phenotype to S. lividans implying that these four genes constitute the whole system.
Multi-objective control and coordination of multi-agent systems (2013)

In this dissertation, control methodologies for systems of multiple mobile agents facing multiple objectives are considered. Carefully constructed ob-jective functions for agents interested in any or all of collision avoidance, robust communications, waypoint following, and dynamic coverage objec-tives are presented. Theory relevant to gradient-like control laws designed using over-approximations of the maximum function is studied and applica-tions of developed controllers in simulations and physical experiments are presented. Agent behavior resulting from and relevant to the various objectives is discussed. Amongst the various objective functions, novel formulations for proximity and global coverage objectives are presented. A novel control law design is developed based on copula structures from multiattribute decision theory. Systematic and intuitive methods for determining the tradeoffs be-tween multiple objectives are presented and applied to the design of multi-
Pituitary Adenylate Cyclase‐Activating Polypeptide (PACAP) Actions on αT3‐1 Gonadotrophs Show Desensitization (1997)

PACAP is a hypothalamic hypophysiotropic factor that acts upon a number of pituitary cells, including gonadotrophs. In the gonadotroph-derived alphaT3-1 cell line, PACAP acts via PVR1 receptors to stimulate adenylyl cyclase and phosphoinositidase C. PACAP-stimulated cAMP accumulation is inhibited by protein kinase C-activating phorbol esters in these cells and the current work was undertaken primarily to establish whether it is also subject to homologous regulation. In acute experiments, PACAP27-stimulated cAMP accumulation (intracellular plus extracellular) was measured (in the presence of phosphodiesterase inhibitor) both in intact cells and in cell membranes. The peptide increased cAMP accumulation, but initial rates of PACAP27-stimulated cAMP accumulation were reduced to between 10 and 50% within 10 min of stimulation in both cells and membranes. The initial rate of forskolin-stimulated cAMP accumulation was maintained in membranes but not in intact cells (although the deviation from linearity was less pronounced than with PACAP27). Thus, rapid homologous desensitization to PACAP27 occurs in intact alphaT3-1 cells, but is not entirely receptor specific. Rapid homologous desensitization of PACAP27-stimulated cAMP accumulation also occurred in the presence of a protein kinase C activating phorbol ester, which inhibited cAMP accumulation without altering the kinetics of the PACAP27 effect. Brief pre-treatment (3 min) with PACAP27 also reduced the ability of PACAP27, but not gonadotrophin-releasing hormone, to cause a spike-type elevation of cytosolic Ca2+ concentration (a consequence of phosphoinositidase C activation). In chronic desensitization studies, pre-treatment for 6 h with PACAP27 caused a dose-dependent (IC50 approximately 10 nM) reduction of PACAP-stimulated cAMP accumulation and down regulated cell surface PVR1 receptors (to approximately 50%). Thus, it appears that PACAP27-stimulated (PVR-1 receptor mediated) adenylyl cyclase undergoes rapid homologous desensitization in alphaT3-1 cells, which is paralleled by homologous desensitization of PACAP27-stimulated phosphoinositidase C activity and involves mechanisms distinct from those underlying heterologous desensitization by phorbol esters. Chronic desensitization of PACAP-stimulated cAMP accumulation and down-regulation of cell surface PVR-1 receptors also occurs in these cells although the receptor loss may not entirely explain the observed desensitization.
Potentiometric, calorimetric and spectroscopic study of copper(II) complexes of leucine-enkephalin and tripeptides containing tyrosine (1992)

Complexation of Copper(II) ion with three peptides containing tyrosine residue (Gly-Gly-L-Tyr, L-Tyr-Gly-Gly and Leucine-enkephalin) was studied by pH-metric, visible spectroscopic measurements at 25°C and 0.2 mol dm-3KNO3, e.s.r spectra and calorimetric technics at 25 ± 0.001°C and I = 0.5 mol dm-3 KNO3. Four species have been reported for Cu(II)-tripeptide systems, while five species have been described in the Cu(II)-Leucine-enkephalin one. The three peptides containing tyrosine display in aqueous solutions the same chelation mode as for simple peptides. Besides, the phenolic hydroxy group in the side chain does not play a direct role in co-ordination to the cupric ion. The MH-2A species of Cu(II)-Leucine-enkephalin system is more stable when compared to the same species of Cu(II)-simple peptide (with no Tyr residue). Moreover, the value of the formation enthalpy of this species is less endothermic, and its entropy variation is more negative, than in the case of L-Tyr-Gly-Gly and Gly-Gly-L-Tyr. These favorable thermodynamic conditions and structural considerations permit to explain the reported high analgesic activity of Cu(II)-Leucine-Enkephalin complexes compared to the free Leucine-Enkephalin analgesic activity.
Prediction of wheat and flour Zeleny sedimentation value using NIR technique. (2003)

Analytical quality parameters of wheat flour prepared from variety and commercial wheat samples (wheat harvest 1998, 1999, 2000 and 2001) were assessed by means of filter spectrograph Inframatic 8620 ASH (moisture and protein content) and Sedi-tester (Zeleny sedimentation value). The spectra of all samples were measured on spectrograph NIRSystem 6500. Calibration equations with cross and independent validation for all analytical characteristics were computed by NIR Software ISI Present WINISI II using MPLS and PLS method. The quality of prediction was evaluated by SEP and r parameters between the measured and the predicted values from cross and independent validation. In case of Inframatic 8620 ASH, validation was realised by NIRPRG software. A statistically significant dependence between the predicted and the measured values of protein content and Zeleny sedimentation (with probability P < 0.01) was determined in both variety and commercial flour sets in the case of cross and independent validation. Better accuracy of prediction was found with NIRSystem 6500. Both important parameters of wheat were successfully predicted by independent validation with nearly the same accuracy.
A Weakly Supervised Adaptive DenseNet for Classifying Thoracic Diseases and Identifying Abnormalities (2018)

We present a weakly supervised deep learning model for classifying thoracic diseases and identifying abnormalities in chest radiography. In this work, instead of learning from medical imaging data with region-level annotations, our model was merely trained on imaging data with image-level labels to classify diseases, and is able to identify abnormal image regions simultaneously. Our model consists of a customized pooling structure and an adaptive DenseNet front-end, which can effectively recognize possible disease features for classification and localization tasks. Our method has been validated on the publicly available ChestX-ray14 dataset. Experimental results have demonstrated that our classification and localization prediction performance achieved significant improvement over the previous models on the ChestX-ray14 dataset. In summary, our network can produce accurate disease classification and localization, which can potentially support clinical decisions.
Thermoacoustic Range Ver in Abdominal Phantom (2021)

Measured and simulated data presented in "Thermoacoustic Range Verification During Pencil Beam Delivery of a Clinical Plan to an Abdominal Imaging Phantom," as resubmitted to the Green J in Dec 2020. RT plan is provided, but system log files are not available to the general public. IBA customers typically have an NDA in place with IBA, and in that case may gain access to log files. Please contact the author (patchTAwork@gmail.com) for assistance setting up paths for kWave software.
Multi-protocol Web Services for enterprises and the Grid (2002)

The Web Services paradigm is a simple model for building web-wide distributed systems using XML and HTTP. However, as the use of this technology expands to include Grid and Enterprise computing, the requirement for higher qualities of service becomes important. To address these requirements, we propose a pluggable framework for using Web services components that allows both static and dynamic invocation of services over multiple protocols. These protocols can include existing reliable technologies such as CORBA/IIOP or new emerging protocols such as BEEP. By moving Web services beyond SOAP, the approach embodied by the Web Services Invocation Framework enables a Web service to be exposed and used over any of a number of protocols whose choice can be made on the basis of the available infrastructure and the required quality of service. A complementary piece of pluggable architecture, the Web Services Gateway, is presented to handle interception of messages coming in to a service. This allows services to be offered over protocols that they were not originally designed for, as well as performing mediation functions as routing, mapping to different protocols, and filtering. Making the gateway itself uses pluggable providers for multiple bindings enables a Web service to be invoked over multiple protocols, while still being able to benefit from the mediation services provided. Providing a Web service with both of the above frameworks enables it to both invoke and be invoked by other artefacts distributed over the network while taking full advantage of the heterogeneity that makes Web services unique. The evolution of this concept is a separation between application logic, which deals in "services" as complete units of available function, and the infrastructure, which may select the best available service over the most appropriate protocol.
60-GHz-band dielectric waveguide filters with cross-coupling for flip-chip modules (2003)

Small-size planar dielectric waveguide filters are presented for 60-GHz-band flip-chip modules. The filters have cross-coupling to introduce an attenuation pole for higher stop-band rejection. We develop two types of three-resonator filters: one has a medium bandwidth and the other has a narrow bandwidth. The former filter shows 1.1-dB insertion loss at a center frequency of 58.3 GHz and 33-dB suppression at a 3-GHz-higher separation. The latter filter shows 3.1-dB insertion loss at a center frequency of 58.4 GHz and a 10-dB-bandwidth of 2.7 GHz. The size of each filter Is 3.4 mm/spl times/3.5 mm.
Regulation of CXCL-8 (Interleukin-8) Induction by Double-Stranded RNA Signaling Pathways during Hepatitis C Virus Infection (2006)

Hepatitis C virus (HCV) infection induces the alpha-chemokine interleukin-8 (CXCL-8), which is regulated at the levels of transcription and mRNA stability. In the current study, CXCL-8 regulation by double-stranded (ds)RNA pathways was analyzed in the context of HCV infection. A constitutively active mutant of the retinoic acid-inducible gene I (RIG-I), RIG-N, activated CXCL-8 transcription. Promoter mutagenesis experiments indicated that NF-kappaB and interferon (IFN)-stimulated response element (ISRE) binding sites were required for the RIG-N induction of CXCL-8 transcription. IFN-beta promoter stimulator 1 (IPS-1) expression also activated CXCL-8 transcription, and mutations of the ISRE and NF-kappaB binding sites reduced and abrogated CXCL-8 transcription, respectively. In the presence of wild-type RIG-I, transfection of JFH-1 RNA or JFH-1 virus infection of Huh7.5.1 cells activated the CXCL-8 promoter. Expression of IFN regulatory factor 3 (IRF-3) stimulated transcription from both full-length and ISRE-driven CXCL-8 promoters. Chromatin immunoprecipitation assays demonstrated that IRF-3 and NF-kappaB bound directly to the CXCL-8 promoter in response to virus infection and dsRNA transfection. RIG-N stabilized CXCL-8 mRNA via the AU-rich element in the 3' untranslated region of CXCL-8 mRNA, leading to an increase in its half-life following tumor necrosis factor alpha induction. The data indicate that HCV infection triggers dsRNA signaling pathways that induce CXCL-8 via transcriptional activation and mRNA stabilization and define a regulatory link between innate antiviral and inflammatory cellular responses to virus infection.