gebhart/patrepeval huggingface dataset:
Effects of Dilution Rate on the Motility and Acrosome Morphology of Boar Spermatozoa Stored at 15 °C (1991)

Contents: The objective of this investigation was to establish the optimal extent of dilution for storage of boar spermatozoa at 15°C in Kiev diluent. The dilution titers used for the sperm‐rich fraction of ejaculates from 8 boars ranged from 1:2 to 1:50. Seminal doses were stored for 10 days. Motility and acrosome morphology were evaluated after 1, 3, 5, 7, and 10 days of storage. The percentages of motile spermatozoa after 24 and 72 hours of storage were significantly higher for dilution rates between 1:7 and 1:11 than for dilution rates lower than 1:7 or higher than 1:11 (p &lt; 0.05). The percentages of spermatozoa with normal acrosomes after 24, 72, and 120 hours of storage were significantly higher for dilution rates between 1:8 and 1:11 than for dilution rates lower than 1:8 or higher than 1:11 (p &lt; 0.01 ).
<title>Photonic MEMS switch applications</title> (2001)

As carriers and service providers continue their quest for profitable network solutions, they have shifted their focus from raw bandwidth to rapid provisioning, delivery and management of revenue generating services. Inherently transparent to data rate the transmission wavelength and data format, MEMS add scalability, reliability, low power and compact size providing flexible solutions to the management and/or fiber channels in long haul, metro, and access networks. MEMS based photonic switches have gone from the lab to commercial availability and are now currently in carrier trials and volume production. 2D MEMS switches offer low up-front deployment costs while remaining scalable to large arrays. They allow for transparent, native protocol transmission. 2D switches enable rapid service turn-up and management for many existing and emerging revenue rich services such as storage connectivity, optical Ethernet, wavelength leasing and optical VPN. As the network services evolve, the larger 3D MEMS switches, which provide greater scalability and flexibility, will become economically viable to serve the ever-increasing needs.
Multicomponent Synthesis of Pyran-2-ylidene Chromium(0) and Tungsten(0) Fischer Carbene Complexes (2010)

A new reaction between chromium(0) and tungsten(0) carbene complexes 1 and alkynyl esters or ketones 2 in the presence of NMO to yield pyran-2-ylidene complexes 3 has been explored. Here, we discuss the scope of the reaction and propose a plausible mechanistic pathway. The method is a new multicomponent approach for the synthesis of pyranylidene carbene complexes.
A Fine Granularity Load Balancing Technique for MMOG Servers Using a KD-Tree to Partition the Space (2009)

MMOGs (massively multiplayer online games) are applications that require high bandwidth connections to work properly. This demand for bandwidth is specially critical on the servers that host the game. This happens because the typical number of simultaneous participants in this kind of game varies from a few hundreds to several tens of thousands, and the server is the one responsible for mediating the interaction between every pair of players connected to it. To deal with this problem, decentralized architectures with multiple servers have been proposed, where each server manages a region of the virtual environment of the game. Each player, then, connects only to the server that manages the region where he is playing. However, to distribute the load among the servers, it is necessary to devise an algorithm for partitioning the virtual environment. In order to readjust the load distribution during the game, this algorithm must be dynamic. Some work has already been made in this direction, but with a geometric algorithm, more appropriate than those found in the literature, it should be possible to reduce the distribution granularity without compromising the rebalancing time, or even reducing it. In this work, we propose the use of a kd-tree for dividing the virtual environment of the game into regions, each of which being designated to one of the servers. The split coordinates of the regions are adjusted dynamically according to the distribution of avatars in the virtual environment. We compared our algorithm to some approaches found in the literature and the simulation results show that our algorithm performed better in most aspects we analyzed.
Generalized Behavior Change During Oppositional Child Training (1981)

Treatment outcome data and demographic information were collected for 140 families which participated in oppositional child treatment based upon differential reinforcement procedures. The dependent measure of generalized child behavior change in the home setting was examined with reference to variations in the following demographic items: age of child, sex of child, race of child, birth order, number of siblings, age of mother, income level of family, educational level of mother, percentage attendance during treatment, and family intactness. Three variables-age of child, percentage attendance during treatment, and family intact-ness-were found to be significantly related to the demonstration of appropriate levels of cooperative behavior in the home.
<title>Pulse-bias modulation of a PbS mosaic array</title> (1979)

Two-dimensional x-y addressed mosaic arrays of more than 12,000 lead-sulfide detectors (64 x 192 detectors in an active area slightly larger than 1/4 by 3/4 inch) have been successfully developed, tested, and demonstrated at Aerojet ElectroSystems Company. This paper describes the pulse-bias modulation concept used to operate the detectors and process their outputs, the design and fabrication techniques used to implement this concept, and the measured performance of these arrays, which was independently verified by the Naval Ocean Systems Center in San Diego.
Effects of cinacalcet on atherosclerotic and nonatherosclerotic cardiovascular events in patients receiving hemodialysis: the EValuation Of Cinacalcet HCl Therapy to Lower CardioVascular Events (EVOLVE) trial (2014)

Wheeler, David C.; London, Gérard M.; Parfrey, Patrick S.; Block, Geoffrey A.; Correa-Rotter, Ricardo; Dehmel, Bastian; Drüeke, Tilman B.; Flöge, Jürgen; Kubo, Yumi; Mahaffey, Kenneth W.; Goodman, William G.; Moe, Sharon M.; Trotman, Marie-Louise; Abdalla, Safa; Chertow, Glenn M.; Herzog, Charles A.; EValuation Of Cinacalcet HCl Therapy to Lower CardioVascular Events (EVOLVE) Trial Investigators
A mixed methods evaluation of staff adherence to client non-attendance (DNA) policy (2016)

This document reports the results of an audit carried out within an Older Adult Community Mental Health Team into the rates of client non-attendance (DNA) and the adherence of staff to the DNA policy. Using a mixed methods approach, the results revealed that the reported DNA rates were significantly lower than the national average. It appeared staff were assessing risk appropriately and implementing action plans, but these were not being adequately documented in the written clinical records. There also appeared to be a lack of clarity regarding the appropriate procedures following patient non-attendance. In view of the results, a number of recommendations have been made.
Structure and functional analysis of a bacterial adhesin sugar-binding domain (2019)

Bacterial adhesins attach their hosts to surfaces through one or more ligand-binding domains. In RTX adhesins, which are localized to the outer membrane of many Gram-negative bacteria via the type I secretion system, we see several examples of a putative sugar-binding domain. Here we have recombinantly expressed one such ~20-kDa domain from the ~340-kDa adhesin found in Marinobacter hydrocarbonoclasticus, an oil-degrading bacterium. The sugar-binding domain was purified from E. coli with a yield of 100 mg/L of culture. Circular dichroism analysis showed that the protein was rich in beta-structure, was moderately heat resistant, and required Ca2+ for proper folding. A crystal structure was obtained in Ca2+ at 1.2-Å resolution, which showed the presence of three Ca2+ ions, two of which were needed for structural integrity and one for binding sugars. Glucose was soaked into the crystal, where it bound to the sugar's two vicinal hydroxyl groups attached to the first and second (C1 and C2) carbons in the pyranose ring. This attraction to glucose caused the protein to bind certain polysaccharide-based column matrices and was used in a simple competitive binding assay to assess the relative affinity of sugars for the protein's ligand-binding site. Fucose, glucose and N-acetylglucosamine bound most tightly, and N-acetylgalactosamine hardly bound at all. Isothermal titration calorimetry was used to determine specific binding affinities, which lie in the 100-μM range. Glycan arrays were tested to expand the range of ligand sugars assayed, and showed that MhPA14 bound preferentially to branched polymers containing terminal sugars highlighted as strong binders in the competitive binding assay. Some of these binders have vicinal hydroxyl groups attached to the C3 and C4 carbons that are sterically equivalent to those presented by the C1 and C2 carbons of glucose.
The alternative health & medicine encyclopedia (1995)

This reference text covers alternative and holistic approaches to maintaining health - biofeedback, acupuncture, hypnosis, herbalism, yoga, chiropractics, massage and other non-traditional treatments. Topics discussed include nutrition, exercise, stress, cancer, sexuality and ageing.
Impaired spliceosomal UsnRNP assembly leads to Sm mRNA down-regulation and Sm protein degradation (2017)

Specialized assembly factors facilitate the formation of many macromolecular complexes in vivo. The formation of Sm core structures of spliceosomal U-rich small nuclear ribonucleoprotein particles (UsnRNPs) requires assembly factors united in protein arginine methyltransferase 5 (PRMT5) and survival motor neuron (SMN) complexes. We demonstrate that perturbations of this assembly machinery trigger complex cellular responses that prevent aggregation of unassembled Sm proteins. Inactivation of the SMN complex results in the initial tailback of Sm proteins on the PRMT5 complex, followed by down-regulation of their encoding mRNAs. In contrast, reduction of pICln, a PRMT5 complex subunit, leads to the retention of newly synthesized Sm proteins on ribosomes and their subsequent lysosomal degradation. Overexpression of Sm proteins under these conditions results in a surplus of Sm proteins over pICln, promoting their aggregation. Our studies identify an elaborate safeguarding system that prevents individual Sm proteins from aggregating, contributing to cellular UsnRNP homeostasis.
Tailings and Mine Waste '04 (2004)

Written by specialists from the mining industry, this collection of over sixty papers from the eleventh annual Tailings and Mine Waste Conference deals with&nbsp;technical capabilities and developments, as well as&nbsp;regulations and environmental concerns.&nbsp;It includes&nbsp;papers on topics such as site characterization, radioactivity and ris
Correlation of Two Accelerated Corrosion Test Methods to the Actual Exposure of Finished Panels (1987)

The standard accelerated corrosion test method is the salt spray test, but there is some question as to its correlation to actual exposure. Coated panels were tested using two accelerated corrosion test methods (salt spray and scab corrosion) and the results compared to panels exposed at Galveston, TX. The tests results showed that the scab corrosion test provided a better simulation of actual exposure than the standard salt spray test method and that the test results from the scab corrosion test could be correlated to actual exposure results.
Structural Studies on Induced Antibodies with Defined Idiotypic Specificities (1978)

Abstract Previous studies in this series have been directed toward the elucidation of the heavy and light chain variable region structures of antibodies raised in A/J mice to the p-azophenylarsonate (Ar) hapten, certain of which bear a cross-reacting idiotype. The present study concerns an analysis of anti-Ar antibodies that arise in A/J mice suppressed for a cross-reacting idiotype. The results indicate that when an idiotype is suppressed and the animal subsequently hyperimmunized, the resultant antibodies are “deviated” into different V-region subgroups, both in the heavy and light polypeptide chains. The study presents the first primary structural analysis of a humoral immune response that has been manipulated by an idiotypic reagent.
Heterogeneity of the human CD4+ T-cell population: two distinct CD4+ T- cell subsets characterized by coexpression of CD45RA and CD45RO isoforms (1996)

Activation of unprimed CD4+CD45RA+/RO- T cells results in a gradual loss of CD45RA expression concomitant with the acquisition of CD45RO. It has been suggested that this conversion occurs in vivo through a CD45RAbright/RObright stage. Next to this small CD45RAbright/RObright subset (Dbright), a larger subpopulation that expresses both RA and RO isoforms at low levels (Ddull) can be found in the circulating CD4+ T-cell population of all donors. The properties of the latter population are largely undefined. Here, we show that Ddull cells have an intermediate phenotype for antigens such as CD31, CD621, CD58, and CD95 that are differentially expressed on unprimed versus primed T cells. In addition, they are able to provide help for B-cell differentiation and contain substantial numbers of tetanus toxoid (TT)-specific precursor cells. Remarkably, both intracellular cytokine staining and analysis of T-cell clones showed that Ddull cells and CD45RO+ T cells produce comparable high amounts of both interferon (IFN)-gamma and interleukin (IL)-4, which clearly distinguishes them from CD45RA+ and Dbright T cells. Finally, prolonged culture of sorted Ddull cells in a mixture of IL-2, IL-6, and tumor necrosis factor (TNF)-alpha showed that about half of the population retained the Ddull phenotype. Part of the cells upregulated the CD45RA isoform, whereas only a minority switched to single CD45RO expression. Our findings indicate that the Ddull population contains primed T cells, some of which may reacquire an "unprimed" phenotype in the absence of antigenic stimulation.
Location-aware mobile applications based on directory services (1997)

Location-aware applications are becoming increasingly attractive due to the widespread dissemination of wireless networks and the emergence of small and cheap locating technologies. We developed a location information server that simplifies and speeds up the development of these applications by offering a set of generic location retrieval and notification services to the application. The data model and the access protocols of these services are based on the X.500 directory service and the lightweight directory access protocol LDAP since these are becoming the standard attribute-value-pair retrieval mechanisms for Internet and Intranet environments. This approach establishes a smooth migration path from conventional to location-aware applications. The paper presents the location information server concepts, defines its directory data model and access services, and discusses the implementation options of the location information server.
A Randomized, Double-Blind, Placebo-Controlled Study of Light Therapy for Antepartum Depression (2011)

clinicaltrials.gov Identifier: NCT01043289.
Nuclear waste glass composition limitations. [Effects of reprocessing plant flowsheets on cost of vitrification] (1984)

This paper discusses the primary considerations involved in nuclear waste glass composition development, explains why the maximum content of certain elements in those glasses is limited, and suggests some possible improvements in reprocessing and waste management practices that might reduce vitrification costs. The basic task is to formulate a glass that can be processed with an acceptably high waste loading and the best possible chemical durability. Problems encountered when certain elements are introduced at higher than acceptable levels include formation of crystalline sludges on the melter floor, increased off-gas system corrosion, and decreased product chemical durability. It is concluded that design decisions that result in reduced amounts of corrosion products and certain soluble neutron poisons, separations process chemicals, and waste handling chemicals in high-level waste (HLW) would, if feasible, reduce vitrification costs. 21 references, 6 figures, 2 tables.
Przyczyny sukcesu lub niepowodzenia w budowaniu państw po pierwszej wojnie światowej: Polska i Czechosłowacja versus Ukraina (2019)

The main goal of this paper is to show the crucial facts which led to the establishment at the end of the First World War of two sovereign states: the First Czechoslovak Republic and the Second Polish Republic. An attempt has also been made to provide background information on the reasons why the Ukraine did not gain independence in the time in question.
Empirical and Strong Coordination via Soft Covering With Polar Codes (2018)

We design polar codes for empirical coordination and strong coordination in two-node networks. Our constructions hinge on the fact that polar codes enable explicit low-complexity schemes for soft covering. We leverage this property to propose explicit and low-complexity coding schemes that achieve the capacity regions of both empirical coordination and strong coordination for sequences of actions taking value in an alphabet of prime cardinality. Our results improve previously known polar coding schemes, which (i) were restricted to uniform distributions and to actions obtained via binary symmetric channels for strong coordination, (ii) required a non-negligible amount of common randomness for empirical coordination, and (iii) assumed that the simulation of discrete memoryless channels could be perfectly implemented. As a by-product of our results, we obtain a polar coding scheme that achieves channel resolvability for an arbitrary discrete memoryless channel whose input alphabet has prime cardinality.
A 1.2 V 12.8 GB/s 2 Gb Mobile Wide-I/O DRAM With 4 $\times$ 128 I/Os Using TSV Based Stacking (2011)

A 1.2 V 1 Gb mobile SDRAM, having 4 channels with 512 DQ pins has been developed with 50 nm technology. It exhibits 330.6 mW read operating power during 4 channel operation, achieving 12.8 GB/s data bandwidth. Test correlation techniques to verify functions through micro bumps and test pads have been developed. Block based dual period refresh scheme is applied to reduce self refresh current with minimum chip size burden. Stacking of 2 dies with 7.5 μm diameter and 40 μm pitch TSVs has been fabricated and tested, which results in 76% overall package yield without difference in performances between top and bottom die.
Network-Wide Heavy Hitter Detection with Commodity Switches (2018)

Many network monitoring tasks identify subsets of traffic that stand out, e.g., top-k flows for a particular statistic. A Protocol Independent Switch Architecture (PISA) switch can identify these "heavy hitter" flows directly in the data plane, by aggregating traffic statistics across packets and comparing against a threshold. However, network operators often want to identify interesting traffic on a network-wide basis. To bridge the gap between line-rate monitoring and network-wide visibility, we present a distributed heavy-hitter detection scheme for networks modeled as one-big switch. We use adaptive thresholds to perform efficient threshold monitoring directly in the data plane. We implement our system using the P4 language, and evaluate it using real-world packet traces. We demonstrate that our solution can accurately detect network-wide heavy hitters with up to 70% savings in communication overhead compared to an existing approach with a provable upper bound.
Assessing Uncertainty in Stratigraphic Correlation: A Stochastic Method Based on Dynamic Time Warping (2014)

We propose a method to manage uncertainties about the layering of 3D reservoir models, using stochastic correlations of sedimentary units identified along wells, according to the sequence stratigraphy paradigm. A stratigraphic model represents the architecture of the stratigraphic succession of an area. Sequence stratigraphy is a common paradigm in reservoir studies to interpret and correlate local high resolution observations (outcrops, well logs and core samples) and more exhaustive but lower resolution data such as 3D seismic. The incompleteness of these data, their quantity and their varying quality, added to the fact that the processes that control the geometry and the conformability of the sequences are complex and poorly known, lead to uncertainties. The proposed method aims at building stratigraphic models honoring 1D interpretations along wells together with conceptual sequence stratigraphic rules formulated quantitatively as correlation costs. The algorithm chosen is a modified version of the Dynamic Time Warping algorithm. More than finding the best correlation using a set of rules, it handles different orders of sequences, takes in account the conformability of the horizons, and its output is a set of different possible correlations, allowing for generating alternative stratigraphic layerings. This methodology is demonstrated on the Teapot Reservoir, Wyoming.
Correlation between α1‐Acid Glycoprotein and Total Sialic Acid in Serum from Dogs with Tumours (1999)

The influence of the acute phase protein alpha 1-acid glycoprotein (AGP) on the concentration of total sialic acid (TSA) in serum was investigated by assessing their degree of correlation in 115 clinically healthy dogs, 29 dogs with malignant mammary tumours, 12 dogs with various other malignant tumours, 12 dogs with benign mammary tumours and 10 dogs with various other benign tumours. Serum from dogs with malignant mammary tumours and other malignant tumours had a statistically significant correlation between AGP and TSA concentrations (Spearman correlation coefficient (rS) = 0.52, P = 0.0005, n = 41). The correlation was also statistically significant in dogs with benign mammary tumours and other benign tumours (rS = 0.48, P = 0.02, n = 22). The Spearman correlation coefficient was 0.51 (P = 0.0001, n = 63) in all dogs with tumours. This was also the case if only those dogs with levels of AGP comparable to healthy dogs (< 750 mg/l) were included in the analysis (rS = 0.42, P = 0.01, n = 56). In clinically healthy dogs, the correlation was not statistically significant (rS = 0.17, P = 0.07, n = 115). None of the four groups of dogs with tumours had changed serum AGP concentrations compared to clinically healthy dogs (all t-tests gave P values above 0.05). The serum concentrations of AGP did not correlate with the clinical stage of dogs with mammary tumours. In conclusion, AGP and TSA concentrations in serum are positively correlated in dogs with tumours, partially explaining the increase in serum TSA in these dogs. Increased sialylation of the AGP molecule in dogs with tumours might contribute to the increased serum TSA levels.