gebhart/patrepeval huggingface dataset:
Run-time Energy Management for Mobiles (2000)

Due to limited energy resources, mobile computing requires an energy-efficient architecture. The dynamic nature of a mobile environment demand an architecture that allowsad ng to (quickly) changing conditions. The mobile has to ad aptd ynamically to new circumstances in the best suitable manner. The hard are and software architecture should be able to support such ad aptability and minimize the energy consumption by making resource allocationd) sions at run-time. To make thesed ecisions e#ective, a tradeoff has to be mad between computation, communicationand initialization costs (both time and energy). This paper dr) bes our approach to construct a mod that supports taking such decisions.
Microstructural Factors Affecting the Deformation Behavior of Mg<sub>12</sub>ZnY LPSO-Phase Alloys (2012)

Microstructural factors that govern the plastic deformation of the long-period stacking ordered (LPSO) phase were clarified. The decrease in length of the long-axis for the plate-like shape of LPSO-phase grains increases the yield stress of the alloy in which basal slip is predominant in deformation. On the other hand, the yield stress tended to increase as the thickness of the plate-like shapes of the grains decreased for the alloy in which the formation of deformation kinks carried the strain.
Engineering electronic properties of layered transition-metal dichalcogenide compounds through alloying (2014)

Binary alloys present a promising venue for band gap engineering and tuning of other mechanical and electronic properties of materials. Here we use the density-functional theory and cluster expansion to investigate the thermodynamic stability and electronic properties of 2D transition metal dichalcogenide (TMD) binary alloys. We find that mixing electron-accepting or electron-donating transition metals with 2D TMD semiconductors leads to degenerate p- or n-doping, respectively, effectively rendering them metallic. We then proceed to investigate the electronic properties of semiconductor-semiconductor alloys. The exploration of the configurational space of the 2D molybdenum-tungsten disulfide (Mo1-xWxS2) alloy beyond the mean field approximation yields insights into anisotropy of the electron and hole effective masses in this material. The effective hole mass in the 2D Mo1-xWxS2 is nearly isotropic and is predicted to change almost linearly with the tungsten concentration x. In contrast, the effective electron mass shows significant spatial anisotropy. The values of the band gap in 2D Mo1-xWxS2 and MoSe2(1-x)S2x are found to be configuration-dependent, exposing the limitations of the mean field approach to band gap analysis in alloys.
High-power picosecond Er +3 /Yb +3 fiber laser (1992)

The unique combination of an active medium, nonlinearity, and negative group velocity dispersion make erbium doped fibers extremely attractive as the basic component of fiber soliton lasers. Recently, we have obtained greatly improved performance in a 1.06-µm pumped fiber amplifier based on Yb3+-sensitized Er3+ doped silica fiber. This development enables the use of readily available high-power solid-state mini-YAG lasers as pump sources and thus considerably scales up the output available from practical fiber lasers. Even more interestingly, the 1-W diode-pumped Nd3+-doped fiber laser recently developed in our laboratories can also be employed as a pump source in an all-fiber tandem-pumping arrangement. We report here a simple, inexpensive high-power fiber laser source based on the new codoped fiber, which is capable of generating transform-limited picosecond pulses with peak powers as high as 200 W.
Solriamfetol improves chronic sleep fragmentation-induced increases in sleep propensity and ameliorates explicit memory in male mice (2023)

Obstructive sleep apnea (OSA) is a highly prevalent condition characterized by episodes of partial or complete breath cessation during sleep that induces sleep fragmentation (SF). One of the frequent manifestations of OSA is the presence of excessive daytime sleepiness (EDS) associated with cognitive deficits. Solriamfetol (SOL) and modafinil (MOD) are wake-promoting agents commonly prescribed to improve wakefulness in OSA patients with EDS. This study aimed to assess the effects of SOL and MOD in a murine model of OSA characterized by periodic SF. Male C57Bl/6J mice were exposed to either control sleep (SC) or SF (mimicking OSA) during the light period (06:00 h to 18:00 h) for 4 weeks, which consistently induces sustained excessive sleepiness during the dark phase. Both groups were then randomly assigned to receive once-daily intraperitoneal injections of SOL (200 mg/kg), MOD (200 mg/kg), or vehicle for 1 week while continuing exposures to SF or SC. Sleep/wake activity and sleep propensity were assessed during the dark phase. Novel Object Recognition test, Elevated-Plus Maze Test, and Forced Swim Test were performed before and after treatment. SOL or MOD decreased sleep propensity in SF, but only SOL induced improvements in explicit memory, while MOD exhibited increased anxiety behaviors. Chronic SF, a major hallmark of OSA, induces EDS in young adult mice that is mitigated by both SOL and MOD. SOL, but not MOD, significantly improves SF-induced cognitive deficits. Increased anxiety behaviors are apparent in MOD-treated mice. Further studies aiming to elucidate the beneficial cognitive effects of SOL are warranted.
Calculation of graft bending angle in anterior cruciate ligament reconstruction (2012)

In ACL reconstruction, position and pose of the ACL is important for clinical outcome after surgery. Among several concerning parameters, graft bending angle affects bungee jump effect. In general intraarticular graft is hopefully perpendicular to the direction of the bone tunnel to prevent from the effect. However, it is difficult to know the angle between the graft and the bone tunnel. This study proposes a calculation method of graft bending angle in virtual model. The experiment used a 3D scanner and an electromagnetic device to obtain 3D profile and 3D motion of the knee, respectively. Then, the profile data is translated to adapt the 3D motion data by using registration method. Finally, an examiner virtually indicates two end points of bone tunnels of the femur and tibia. The virtual graft bending angle is calculated from them. The results compared change of bending angle of transtibial and far anteromedial techniques. As a result, the proposed method could calculate the bending angle in simulation. A future work is to explore the proper bone tunnels automatically.
Toxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes (2005)

Prokaryotic chromosomes code for toxin-antitoxin (TA) loci, often in multiple copies. In E.coli, experimental evidence indicates that TA loci are stress-response elements that help cells survive unfavorable growth conditions. The first gene in a TA operon codes for an antitoxin that combines with and neutralizes a regulatory 'toxin', encoded by the second gene. RelE and MazF toxins are regulators of translation that cleave mRNA and function, in interplay with tmRNA, in quality control of gene expression. Here, we present the results from an exhaustive search for TA loci in 126 completely sequenced prokaryotic genomes (16 archaea and 110 bacteria). We identified 671 TA loci belonging to the seven known TA gene families. Surprisingly, obligate intracellular organisms were devoid of TA loci, whereas free-living slowly growing prokaryotes had particularly many (38 in Mycobacterium tuberculosis and 43 in Nitrosomonas europaea). In many cases, TA loci were clustered and closely linked to mobile genetic elements. In the most extreme of these cases, all 13 TA loci of Vibrio cholerae were bona fide integron elements located in the V.cholerae mega-integron. These observations strongly suggest that TA loci are mobile cassettes that move frequently within and between chromosomes and also lend support to the hypothesis that TA loci function as stress-response elements beneficial to free-living prokaryotes.
Metal-substituted silacyclobutanes. 2. Derivatives of silicon, germanium, and tin (1978)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMetal-substituted silacyclobutanes. 2. Derivatives of silicon, germanium, and tinC. S. Cundy, M. F. Lappert, and Choi-Kwan YuenCite this: Inorg. Chem. 1978, 17, 4, 1092–1093Publication Date (Print):April 1, 1978Publication History Published online1 May 2002Published inissue 1 April 1978https://pubs.acs.org/doi/10.1021/ic50182a061https://doi.org/10.1021/ic50182a061research-articleACS PublicationsRequest reuse permissionsArticle Views38Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Neural regulation of slow-wave frequency in the murine gastric antrum (2005)

Gastric peristaltic contractions are driven by electrical slow waves modulated by neural and humoral inputs. Excitatory neural input comes primarily from cholinergic motor neurons, but ACh causes depolarization and chronotropic effects that might disrupt the normal proximal-to-distal spread of gastric slow waves. We used intracellular electrical recording techniques to study cholinergic responses in stomach tissues from wild-type and W/W(V) mice. Electrical field stimulation (5 Hz) enhanced slow-wave frequency. These effects were abolished by atropine and the muscarinic M(3)-receptor antagonist 4-diphenylacetoxy-N-methylpiperidine methiodide. ACh released from nerves did not depolarize antral muscles. At higher rates of stimulation (10 Hz), chronotropic effects were mediated by ACh and a noncholinergic transmitter and blocked by muscarinic antagonists and neurokinin (NK(1) and NK(2))-receptor antagonists. Neostigmine enhanced slow-wave frequency, suggesting that the frequency of antral pacemakers is kept low by efficient metabolism of ACh. Neostigmine had no effect on slow-wave frequency in muscles of W/W(v) mice, which lack intramuscular interstitial cells of Cajal (ICC-IM). These muscles also showed no significant chronotropic response to 5-Hz electrical field stimulation or the cholinergic agonist carbachol. The data suggest that the chronotropic effects of cholinergic nerve stimulation occur via ICC-IM in the murine stomach. The capacity of gastric muscles to metabolize ACh released from enteric motor neurons contributes to the maintenance of the proximal-to-distal slow-wave frequency gradient in the murine stomach. ICC-IM play a critical role in neural regulation of gastric motility, and ICC-IM become the dominant pacemaker cells during sustained cholinergic drive.
Coronary Revascularization Rather than Cardiac Transplantation for Chronic Ischemic Cardiomyopathy (1989)

Patients with very poor ventricular function have been thought to be highly vulnerable to elective myocardial revascularization. Ischemic cardiomyopathy is now the major indication for cardiac transplantation. The 2-year survival of medically treated patients with ejection fractions less than 20%, but who are not sufficiently symptomatic for cardiac transplantation, is less than 25%. At our institution we have taken an aggressive approach by using myocardial revascularization for chronic ischemic cardiomyopathy. Between 1983 and 1988, 39 patients with preoperative ejection fractions less than 20% underwent coronary artery bypass. Patients were excluded if they had valvular heart disease other than mild to moderate mitral regurgitation, required resection of a left ventricular aneurysm, or required emergency operation for acute coronary occlusion. Mean age was 63.3 years (range, 43 to 80 years) and 31 were men. Mean preoperative ejection fraction was 18.3% (range, 10% to 20%) and the mean preoperative left ventricular end diastolic pressure was 22 mm Hg (range, 8 mm Hg to 38 mm Hg). There was one operative death (2.6%). Mean follow-up was 21 months (range, 3 to 60 months) with eight late deaths (a total mortality rate of 21%). Seven deaths were due to arrhythmias. Three patients continued to have severe heart failure, one of whom underwent successful cardiac transplantation. By life table analysis, there was a 3-year survival rate of 83%. With the present shortage of cardiac transplant donors, myocardial revascularization for ischemic cardiomyopathy is a reasonably effective means for preserving residual ventricular function.
ENS-10: A Dataset For Post-Processing Ensemble Weather Forecasts (2022)

Post-processing ensemble prediction systems can improve the reliability of weather forecasting, especially for extreme event prediction. In recent years, different machine learning models have been developed to improve the quality of weather post-processing. However, these models require a comprehensive dataset of weather simulations to produce high-accuracy results, which comes at a high computational cost to generate. This paper introduces the ENS-10 dataset, consisting of ten ensemble members spanning 20 years (1998-2017). The ensemble members are generated by perturbing numerical weather simulations to capture the chaotic behavior of the Earth. To represent the three-dimensional state of the atmosphere, ENS-10 provides the most relevant atmospheric variables at 11 distinct pressure levels and the surface at 0.5-degree resolution for forecast lead times T=0, 24, and 48 hours (two data points per week). We propose the ENS-10 prediction correction task for improving the forecast quality at a 48-hour lead time through ensemble post-processing. We provide a set of baselines and compare their skill at correcting the predictions of three important atmospheric variables. Moreover, we measure the baselines' skill at improving predictions of extreme weather events using our dataset. The ENS-10 dataset is available under the Creative Commons Attribution 4.0 International (CC BY 4.0) license.
Effects of Dietary Resveratrol on the Sleep-Wake Cycle in the Non-Human Primate Gray Mouse Lemur (Microcebus murinus)* (2012)

Converging evidence shows that the non-human primate gray mouse lemur (Microcebus murinus) is ideal for the study of the aging process and for testing the effects of new therapies and dietary interventions on age-associated pathologies. One such dietary supplement is resveratrol (RSV), a dietary polyphenolic compound with several positive effects on metabolic functions and longevity. However, little is known about the effect of RSV on the lemur sleep-wake cycle, which reflects mammalian brain function and health. In the present study, the authors investigated this effect by comparing sleep-wake cycles in adult lemurs based on electroencephalographic (EEG) rhythms. The effect of short-term RSV supplementation on the sleep-wake cycle of mouse lemurs was evaluated in entrained conditions (long-day photoperiods, light:dark 14:10). After 3 wks of RSV supplementation, the animals exhibited a significantly increased proportion of active-wake time, occurring mainly during the resting phase of the sleep-wake cycle (+163%). The increase in active-wake time with RSV supplementation was accompanied by a significant reduction of both paradoxical sleep (-95%) and slow-wave sleep (-38%). These changes mainly occurred during the resting phase of the sleep-wake cycle (RSV supplementation induced negligible changes in active-wake time during the active phase of the sleep-wake cycle). The present data suggest that RSV may be a potent regulator of sleep-wake rhythms and could be of major interest in the study of sleep perturbations associated with aging and neuropathology.
Dual Fluorescence from an Isonido ReIII Rhenacarborane Phosphine Complex, [7,10-μ-H-7-CO-7,7-(PPh3)2-isonido-7,8,9-ReC2B7H9] (2006)

The complex [7,10-mu-H-7-CO-7,7-(PPh3)2-isonido-7,8,9-ReC2B7H9] has been synthesized by treatment of the complex salt [NHMe3][3,3-Cl2-3,3-(CO)2-closo-3,1,2-ReC2B9H11] with PPh3 in refluxing THF (tetrahydrofuran) and isolated as intensely colored orange-red microcrystals. Spectroscopic NMR and IR data have suggested that the product has a highly asymmetric structure with two inequivalent PPh3 ligands and a single CO ligand. Measurement of 11B NMR spectra in particular have indicated seven distinct boron vertexes, although the resulting cage degradation by removal of two BH vertexes was confirmed only following X-ray crystallographic analysis, which revealed the pentadecahedral isonido-7,8,9-ReC2B7 architecture. The 11B NMR resonances span an enormous chemical shift range (Deltadelta = 113), and this appears to be a direct consequence of the deshielding of the boron vertex directly opposite the quadrilateral |ReCCB| aperture. The new complex has been shown by electrochemical measurements to undergo a reversible one-electron oxidation. Digitally simulated cyclic voltammograms support a proposed square scheme (E(1/2) = 0.58, 0.69 V vs ferrocene) involving a reversible isonido-closo transition of the metallacarborane cage. Most unusually for a metallacarborane complex, ambient temperature solutions in CH2Cl2 and DMF have been shown to be intensely turquoise-blue fluorescent (lambda(em) = 442 nm, Phi = 0.012). Fluorescence spectroscopy measurements in MeTHF (2-methyltetrahydrofuran) glass at 77 K have indicated that the likely cause of such a broad emission is dual fluorescence (lambda(em) = 404, 505 nm), with both emissions displaying vibronic structure. Following excited-state lifetime decay analysis, the emissive behavior has been accredited to metal-perturbed 1IL states, with the lower energy emission arising from a slight geometric distortion of the initially excited complex.
Electroporation improves transfection efficiency in rat wound healing model (2004)

Abstract Introduction: We are investigating the use of electroporation in vivo to enhance transfection efficiency and improve wound healing with DNA plasmid expression vectors for growth factors. Methods: For electroporation (EP) transfection efficiency and wound healing we used luciferase and keratinocyte growth factor (KGF) DNA plasmid expression vectors respectively (gWIZ-Lux vector controlled by CMV promoter, Invitrogen, Carlsbad, CA). Animals were electroporated at the site of injection within two minutes of plasmid administration, using a square wave electroporator (ECM 830, BTX Genetronics, San Diego, CA). For luciferase, photon emission was quantified using the IVIS Imaging System (Xenogen Corporation, Alameda, CA). For the KGF experiment, healing 4 cutaneous 8mm punch biopsies was assessed using image analysis software based on NIH image (Scion Image, Frederick, MD). A Sprague Dawley rat sepsis model of wound healing with partial cecal ligation was utilized. We found in previous experiments that wound healing was delayed in septic animals. Results: Single EP enhanced average luciferase expression three-fold compared to plasmid without EP (p 5 ± SEM (photons/sec). Values were recorded as total photon flux from each wound, with 4 wounds per rat. Wound size values represent average ± SEM (pixels). Conclusions: These results encourage us to explore further the possible benefit of electroporation-facilitated transfection of growth factors to improve wound healing.
Sealing Metal and Ceramic Parts by Forming Reactive Alloys (1957)

Metal and ceramic parts are sealed by introducing a molten solder or by inserting a thin sheet of metal that will form a reactive alloy. A wide choice of materials can be used, including many that seal at high temperatures with little metallic evaporation. Materials can be used that can be predegassed at temperatures considerably above those used for final sealing. The seals can be made in vacuum or in an inert gas. The parts can be stacked one on the other so that a multiplicity of seals can be made at the same time. By using a metal such as titanium, and ceramic parts having an expansion characteristic similar to that of titanium, seals can be made that are strong and can operate for many hours at temperatures as high as 800°C.
A model of insulin fibrils derived from the x‐ray crystal structure of a monomeric insulin (despentapeptide insulin) (1997)

The crystal structure of despentapeptide insulin, a monomeric insulin, has been refined at 1.3 Å spacing and subsequently used to predict and model the organization in the insulin fibril. The model makes use of the contacts in the densely packed despentapeptide insulin crystal, and takes into account other experimental evidence, including binding studies with Congo red. The dimensions of this model fibril correspond well with those measured experimentally, and the monomer–monomer contacts within the fibril are in accordance with the known physical chemistry of insulin fibrils. Using this model, it may be possible to predict mutations in insulin that might alleviate problems associated with fibril formation during insulin therapy. © 1997 Wiley-Liss Inc.
Three-Level AC–DC–AC Z-Source Converter Using Reduced Passive Component Count (2009)

This paper presents a three-level AC-DC-AC Z-source converter with output voltage buck-boost capability. The converter is implemented by connecting a low-cost front-end diode rectifier to a neutral-point-clamped inverter through a single X-shaped <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">LC</i> impedance network. The inverter is controlled to switch with a three-level output voltage, where the middle neutral potential is uniquely tapped from the star-point of a wye-connected capacitive filter placed before the front-end diode rectifier for input current filtering. Through careful control, the resulting converter can produce the correct volt-second average at its output, while simultaneously achieving inductive voltage boosting by shooting through either an appropriately selected inverter phase-leg or two phase-legs being commanded simultaneously. More interestingly, these performance features are achieved with no increase in the number of semiconductor commutations, and hence, no increase in switching losses. The proposed converter therefore offers a low-cost alternative to applications that need to ride through frequent input voltage sags. For confirming the converter performance, experimental testing using a constructed laboratory prototype is performed with its captured results presented in a later section of the paper.