gebhart/patrepeval huggingface dataset:
Processing of single walled carbon nanotubes for nanocomposites. (2007)

An existing electric arc discharge (EAD) apparatus was found to produce only small quantities of single-walled carbon nanotubes (SWNT), therefore an in depth evaluation of the various parameters was performed in order to optimize the SWNT yield. A systematic study on the current applied (48-116 A) and morphology of the arc during EAD experiments was performed, a study of this type has not been previously reported in literature. Our findings include that the current being applied to the electrodes, as controlled by a commercial software program, was &sim; 20 A lower than expected. Currents in the range of 70-90 A appear to be optimal for this EAD system as the yield of SWNT is consistent with commercially produced SWNT also fabricated with an EAD system. During the experiments, the current was not constant, but fluctuated over a range of values, 7-20 A ranges were not uncommon. Concurrently, the gap between the electrodes was also non-constant, a gap of less than 1 mm or contact as the anode stabs the cathode was witnessed. Subsequent analysis of the yield of SVVNT, as a function of the current as well as the physical location in the EAD chamber where the yield was greatest, was performed with simultaneous thermogravimetric analysis and differential thermal analysis. Significant differences in the concentration of metal catalysts used to fabricate the SWNT were observed between sample areas in the chamber. Moreover, an anomalous peak was observed in the differential thermal analysis trace between the 350-400&deg;C. Subsequent analysis of relevant constituent materials was investigated to identify the cause of this anomaly. Static and dynamic mechanical analysis was performed on highly drawn fibers of neat polystyrene and its composites containing 0.3 wt.% of a commercial SWNT containing soot. Though the dynamic and static measurements of fibers in the 130-150 mum did not show improvement with the addition of the filler, composite fibers of 20-50 mum were statistically higher in strain to break over the neat fibers. Moreover, these composite fibers had a ten-fold higher strain to break than those in the 130-150 mum.
Nonlinear behavior of a passive zero-spring-rate suspension system (1991)

Various concepts for advanced syspension systems have been proposed for counteracting gravity loads in ground vibration testing of large space structures. Approximating the flight modes of a low-frequency flexible structure in a ground test requires a very soft suspension system. The dynamic behavior of a passive zero-spring-rate mechanism, sometimes used for such ground testing, is analyzed. This mechanism reduces the stiffness inherent in suspending a test specimen by cables. However, the mechanism is shown to be sensitive to imperfections. Imperfections can initiate nonlinear behavior which becomes more pronounced at lower operating frequencies. Furthermore, large pendular motion of the suspension system couples with the vertical motion, producing additional nonlinearity.
Administration of bortezomib before and after autologous stem cell transplantation improves outcome in multiple myeloma patients with deletion 17p (2011)

In patients with multiple myeloma (MM), risk stratification by chromosomal abnormalities may enable a more rational selection of therapeutic approaches. In the present study, we analyzed the prognostic value of 12 chromosomal abnormalities in a series of 354 MM patients treated within the HOVON-65/GMMG-HD4 trial. Because of the 2-arm design of the study, we were able to analyze the effect of a bortezomib-based treatment before and after autologous stem cell transplantation (arm B) compared with standard treatment without bortezomib (arm A). For allanalyzed chromosomal aberrations, progression-free survival (PFS) and overall survival (OS) were at least equal or superior in the bortezomib arm compared with the standard arm. Strikingly, patients with del(17p13) benefited the most from the bortezomib-containing treatment: the median PFS in arm A was 12.0 months and in arm B it was 26.2 months (P = .024); the 3 year-OS for arm A was 17% and for arm B it was 69% (P = .028). After multivariate analysis, del(17p13) was an independent predictor for PFS (P < .0001) and OS (P < .0001) in arm A, whereas no statistically significant effect on PFS (P = .28) or OS (P = .12) was seen in arm B. In conclusion, the adverse impact of del(17p13) on PFS and OS could be significantly reduced by bortezomib-based treatment, suggesting that long-term administration of bortezomib should be recommended for patients carrying del(17p13).
MIF (macrophage migration inhibitory factor (glycosylation-inhibiting factor)) (2011)

Review on MIF (macrophage migration inhibitory factor (glycosylation-inhibiting factor)), with data on DNA, on the protein encoded, and where the gene is implicated.
Video-rate full-field optical coherence reflectometry by use of a pair of CCD cameras (2002)

We demonstrate that horizontal cross-sectional images can be obtained at video rate by operating a pair of CCD cameras as heterodyne detector arrays in optical low-coherence reflectometry. Application to three-dimensional microscopy is presented.
LEACHING GOLD WITH THIOSULPHATE SOLUTION CONTAINING ADDED SODIUM CHIORIDE AND SODIUM DODECYL SULPHONATE (1998)

The optimization of conditions of leaching gold from oxide ore in Hubei province with thiosulphate solutions containing added NaCl and no Cu+ has been explored The leached fraction of gold can go up to 98% with solution of [S2O32-]=08mol/L, =1～2mol/L, =10mol/L at 50℃ for 3h Two sulphide concentrates from Shandong and Guangdong provinces are tested, and the leaching percentage can go up to 96% and 93% respectively with the solution of [S2O32-]=08mol/L, =1～2mol/L, =10mol/L, sodium dodecyl sulphonate 110 mmol/L at 50℃ for 3h
A novel somatostatin conjugate with a high affinity to all five somatostatin receptor subtypes (2002)

This conjugate has a long circulation half-life (i.e., approximately 27 hours after subcutaneous administration in mice) and, with high SRS pan-affinity demonstrated in this study, it has potential in the therapy of SRS-positive tumors. Currently, the clinical significance of SMS-dextran70 is being explored in a clinical Phase I-II study of patients with hormone-refractory prostate cancer. The outcome of this study will be reported when it is available.
In vitro and in vivo activities of DQ-2556 and its mode of action (1992)

DQ-2556 is a recently developed cephalosporin with a broad spectrum of antibacterial activity against both gram-positive and gram-negative bacteria. Its in vitro activity was roughly comparable to those of cefuzonam and cefpirome and greater than those of ceftazidime, cefepime, and cefclidin against gram-positive bacteria. Against gram-negative bacteria, DQ-2556 showed almost the same activity as those shown by cefpirome and cefepime. The activity was largely unaffected by culture medium pH or the addition of human serum. The protective effect of DQ-2556 in experimental gram-positive pathogen and Escherichia coli infections in mice was greater than those of ceftazidime, cefuzonam, cefepime, and cefclidin and was similar to that of cefpirome. Against Pseudomonas aeruginosa and Acinetobacter calcoaceticus infections, DQ-2556 was more active than cefuzonam and had activity similar to or less than those of ceftazidime, cefpirome, cefepime, and cefclidin. When cells of E. coli were exposed to various concentrations of DQ-2556, filamentous cells were observed at concentrations of 0.0008 micrograms/ml and greater, spheroplasts started to form at 0.025 micrograms/ml, and subsequent cell lysis was observed. The affinity of DQ-2556 to PBP 3 of E. coli, which participates in septum formation, as suggested by morphological observation, was two times greater than that of ceftazidime. DQ-2556 also had high affinities for PBPs 1B and 1A of E. coli. These results suggest that DQ-2556 is worthy for subsequent clinical trials.
Lie group integrators for animation and control of vehicles (2009)

This article is concerned with the animation and control of vehicles with complex dynamics such as helicopters, boats, and cars. Motivated by recent developments in discrete geometric mechanics, we develop a general framework for integrating the dynamics of holonomic and nonholonomic vehicles by preserving their state-space geometry and motion invariants. We demonstrate that the resulting integration schemes are superior to standard methods in numerical robustness and efficiency, and can be applied to many types of vehicles. In addition, we show how to use this framework in an optimal control setting to automatically compute accurate and realistic motions for arbitrary user-specified constraints.
Proposal of an optical fiber scanner for high-speed and compact laser marking systems (2019)

We propose an optical fiber scanner suitable for high-power industrial laser marking systems. The proposed optical scanner enables beam scanning by resonating the optical fiber end with an electric actuator. As our optical scanner is extremely compact and lightweight, high-speed operation can be expected compared with the conventional galvanometer-type optical scanner. In this paper, novel monitoring and compensation techniques of the beam scanning path utilizing a position-sensitive detector in order to compensate for the manufacturing errors of optical fiber scanners are discussed. We demonstrate that the beam can be scanned linearly at a resonance frequency of about 10 kHz by appropriately controlling the amplitude and phase difference of the applied voltage.
Tension Tests on Driven H-Piles in Sand and Clay (2015)

In most soils, driven H-Piles are generally considered as small displacement piles, that is, the volume of soil displaced during installation is generally small. In most soils the installation of H-Piles likely progresses without significant plugging and the pile advances giving full contact of soil along the web and between the flanges. Very little is known about the tension behavior of H-Piles in these soils. In order to evaluate the uplift capacity for use as foundations for solar panels arrays, tension tests were performed on driven H-Piles at six different test sites. The embedded lengths of the piles varied from 2.4 to 3 m (8 to 10 ft.). The sites consisted of a range of soils, from uniform clean medium sand, silty fine sand and silty clay and included both saturated and unsaturated site conditions. Short term tension tests (1 day and 7 day) to failure were conducted at each site. Examples of the installation driving records are also shown. The unit side resistance of the piles was evaluated assuming both full soil movement (plugged) and no soil movement (unplugged) during loading for each test. It is suggested that the unit side resistance may relate to the Effective Area Ratio of the piles.
Three principles of representation for semantic networks (1982)

Semantic networks are so intuitive and easy to use that they are often employed without much thought as to the phenomenon of semantic nets themselves. Since they are becoming more and more a tool of artificial intelligence and now database technology, it is appropriate to focus on the principles of semantic nets. Such focus finds a harmonious and consistent base which can increase the semantic quality and usefulness of such nets. Three rules of representation are presented which achieve greater conceptual simplicity for users, simplifications in semantic net implementations and maintenance, and greater consistency across semantic net applications. These rules, applied to elements of the net itself, reveal how fundamental structures should be organized, and show that the common labeled-edge semantic net can be derived from a more primitive structure involving only nodes and membership relationships (and special nodes which represent names). Also, the correlation between binary and n -ary relations is presented.
2014 HPC Annual Report (2014)

Our commitment is to support you through delivery of an IT environment that provides mission value by transforming the way you use, protect, and access information. We approach this through technical innovation, risk management, and relationships with our workforce, Laboratories leadership, and policy makers nationwide. This second edition of our HPC Annual Report continues our commitment to communicate the details and impact of Sandia’s large-scale computing resources that support the programs associated with our diverse mission areas. A key tenet to our approach is to work with our mission partners to understand and anticipate their requirements and formulate an investment strategy that is aligned with those Laboratories priorities. In doing this, our investments include not only expanding the resources available for scientific computing and modeling and simulation, but also acquiring large-scale systems for data analytics, cloud computing, and Emulytics. We are also investigating new computer architectures in our advanced systems test bed to guide future platform designs and prepare for changes in our code development models. Our initial investments in large-scale institutional platforms that are optimized for Informatics and Emulytics work are serving a diverse customer base. We anticipate continued growth and expansion of these resources in the coming years as the use of these analytic techniques expands across our mission space. If your program could benefit from an investment in innovative systems, please work through your Program Management Unit ’s Mission Computing Council representatives to engage our teams.
Dynamic deformation measurement of real bridge using sampling moire camera (2013)

Sampling moire method is one of the convenient phase analysis methods. The accuracy of phase difference analysis is from 1/100 to 1/1000 of the grating pitches. This method is useful to a real-time measurement because the phase analysis can be performed from a single-shot image. In this paper, we developed a sampling moire camera which can analyze grating phase in real-time. This camera can measure dynamic deformation of a structure in real-time. Applications for dynamic deformation measurement of a real bridge are demonstrated.
Addressing Mobile Agent Security through Agent Collaboration (2007)

The use of agent paradigm in today's applications is hampered by the security concerns of agents and hosts alike. The agents require the presence of a secure and trusted execution environment; while hosts aim at preventing the execution of potentially malicious code. In general, hosts support the migration of agents through the provision of an agent server and managing the activities of arriving agents on the host. Numerous studies have been conducted to address the security concerns present in the mobile agent paradigm with a strong focus on the theoretical aspect of the problem. Various proposals in Intrusion Detection Systems aim at securing hosts in traditional client-server execution environments. The use of such proposals to address the security of agent hosts is not desirable since migrating agents typically execute on hosts as a separate thread of the agent server process. Agent servers are open to the execution of virtually any migrating agent; thus the intent or tasks of such agents cannot be known a priori. It is also conceivable that migrating agents may wish to hide their intentions from agent servers. In light of these observations, this work attempts to bridge the gap from theory to practice by analyzing the security mechanisms available in Aglet. We lay the foundation for implementation of application specific protocols dotted with access control, secured communication and ability to detect tampering of agent data. As agents exists in a distributed environment, our proposal also introduces a novel security framework to address the security concerns of hosts through collaboration and pattern matching even in the presence of differing views of the system. The introduced framework has been implemented on the Aglet platform and evaluated in terms of accuracy, false positive, and false negative rates along with its performance strain on the system.
A fundamental subdivision of circulating lymphocytes defined by adhesion to mucosal addressin cell adhesion molecule-1. Comparison with vascular cell adhesion molecule-1 and correlation with β 7 integrins and memory differentiation (1996)

The leukocyte integrin alpha 4 beta 7 is a receptor for the vascular mucosal addressin cell adhesion molecule-1 (MAdCAM-1). Most circulating B and T lymphocytes in man are alpha 4+, and on these cells the regulated display of the beta 7 integrin chain determines the expression of alpha 4 beta 7 and, in large part, binding to MAdCAM-1. Among CD4+ T cells, beta 7 high memory cells (including the L-selectin+ subset) bind MAdCAM-1 better than beta 7int naive cells; whereas beta 7- memory cells,including skin homing lymphocytes, interact poorly if at all. Circulating alpha E beta 7+ T cells are alpha 4 beta 7high and also bind MAdCAM-1 well. B cells are also subdivided by beta 7 expression, and beta 7+ B cells bind MAdCAM-1 better than the beta 7low/- subset. The related vascular ligand vascular cell adhesion molecule-1 (VCAM-1), expressed on endothelium primarily in nonmucosal sites of inflammation, interacts with blood lymphocytes (including beta 7high T cells) almost exclusively via alpha 4 beta 1 and binds beta 7low/-(beta 1high) better than beta 7+ B cells and memory cells better than naive CD4+ cells. beta 7-(beta 1high) memory T cells are somewhat enriched over beta 7high memory cells at low (but not at high) VCAM-1 densities. Interestingly, CD56+ NK cells, which express both alpha 4 beta 7 and alpha 4 beta 1, bind well to VCAM-1 but poorly to MAdCAM-1. The findings indicate that the display and function of alpha 4 beta 7 determine integrin-dependent blood lymphocyte interactions with MAdCAM-1, thus delineating discrete mucosal vs nonmucosal lymphocyte populations in vivo; that alpha 4 beta 1 dominates blood lymphocyte interactions with VCAM-1; and that quantitative and qualitative regulation of MAdCAM-1 vs VCAM-1 can critically control the recruitment of specialized lymphocyte subsets during inflammation.
Autonomic modulation of ventricular rate in atrial fibrillation (1997)

This study investigated the changes in R-R interval in 23 patients (11 men and 12 women; mean age 61 yr) with persistent atrial fibrillation in response to several provocative maneuvers including active postural change, Valsalva maneuver, handgrip, and rhythm-controlled respiration. Averaged R-R intervals were shortened immediately after postural change (from 797 +/- 35 ms supine to 677 +/- 27 ms standing; P < 0.01) and recovered to the 90% level within 100 s. During Valsalva strain and handgrip, mean R-R intervals were significantly shortened (from 737 +/- 37 ms sitting to 697 +/- 38 ms in Valsalva and from 773 +/- 68 ms sitting to 701 +/- 58 ms in handgrip; both P < 0.01). During rhythm-controlled respiration, only two cases (10.5%) showed power peaks in spectrograms of moving-window-averaged R-R intervals at the frequency corresponding to respiration rhythm. The ventricular response to atrial fibrillation is influenced by an increase in sympathetic tone and a decrease in parasympathetic tone but is not necessarily influenced by the increase in parasympathetic dominance. These results suggest that even in atrial fibrillation patients, the autonomic nervous system modulates the ventricular rate via the atrioventricular node and atrial tissue.
TRADITIONAL VERSUS NONTRADITIONAL RISK FACTORS FOR CARDIOVASCULAR EVENTS IN KIDNEY TRANSPLANT RECIPIENTS (2008)

Woodle, E S.; Rike, A H.; Everly, J; Alloway, R R.; Mogilishetty, G; Cardi, M; Clippard, M; Munda, R Author Information
Serial concatenation of interleaved codes: analytical performance bounds (2002)

Parallel concatenated coding schemes employing convolutional codes as constituent codes linked by an interleaver have been proposed in the literature as "turbo codes". They yield very good performance in connection with simple suboptimum decoding algorithms. In this paper, we propose an alternative scheme consisting of the serial concatenation of block or convolutional codes and evaluate its average performance in terms of analytical bounds on the bit error probability. Comparisons with parallel concatenated coding schemes show in some cases sensible advantages.
Benzodiazepine-induced superoxide signalsB cell apoptosis: mechanistic insight and potential therapeutic utility (2002)

The properties of a proapoptotic 1,4-benzodiazepine, Bz-423, identified through combinatorial chemistry and phenotype screening are described. Bz-423 rapidly generated superoxide (O2–) in transformed Ramos B cells. This O2– response originated from mitochondria prior to mitochondrial transmembrane gradient collapse and opening of the permeability transition pore. Bz-423–induced O2– functioned as an upstream signal that initiated an apoptotic program characterized by cytochrome c release, mitochondrial depolarization, and caspase activation. Pretreatment of cells with agents that either block the formation of Bz-423–induced O2– or scavenge free radicals attenuated the death cascade, which demonstrated that cell killing by Bz-423 depends on O2–. Parallels between Ramos cells and germinal center B cells prompted experiments to determine whether Bz-423 had therapeutic activity in vivo. This possibility was tested using the (NZB × NZW)F1 murine model of lupus, in which the pathologically enhanced survival and expansion of germinal center B cells mediate disease. Administration of Bz-423 for 12 weeks specifically controlled germinal center hyperplasia and reduced the histological evidence of glomerulonephritis. Collectively, these studies define a new structure-function relationship for benzodiazepines and point to a new target and mechanism that could be of value for developing improved drugs to manage systemic lupus erythematosus and related disorders.
Characterization of a fragment of bovine von Willebrand factor that binds to platelets (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCharacterization of a fragment of bovine von Willebrand factor that binds to plateletsMary Ann Mascelli, Thomas S. Edgington, and Edward P. KirbyCite this: Biochemistry 1986, 25, 20, 6325–6335Publication Date (Print):October 7, 1986Publication History Published online1 May 2002Published inissue 7 October 1986https://pubs.acs.org/doi/10.1021/bi00368a074https://doi.org/10.1021/bi00368a074research-articleACS PublicationsRequest reuse permissionsArticle Views34Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts