gebhart/patrepeval huggingface dataset:
P27. Induction but not extrapleural pneumonectomy may be important in the treatment for stage IVa thymoma (2015)

BACKGROUND: To retrospectively evaluate the results of surgical resection, including extrapleural pneumonectomy (EPP) and local resection (LR) of pleural implants, in combination with adjuvant radiotherapy with or without induction therapy for the treatment of Masaoka stage IVa thymoma in our institution. METHODS: From October 2008 to October 2014, 15 consecutive patients with stage IVa thymoma underwent radical resection followed by adjuvant radiotherapy. Eight patients had neoadjuvant chemo or chemoradiotherapy and the rest had no induction. Extrapleural pneumonectomy (EPP) was performed on one patient in the induction group and two in the non-induction group. The other patients had extended thymectomy plus local resection (LR) of invaded organs and pleural/pericardial implants. Median follow-up duration was 23 months (interquartile range, 18–30 months). Perioperative results and recurrence free survival were analyzed. RESULTS: Overall mortality and in-hospital morbidity were 0% and 33.3% respectively. In the induction group, the response rate was 50% (three partial responses and one complete pathological response). In-hospital morbidity was insignificantly more favorable in the induction group (12.5% vs. 57.1%, P=0.10, Fisher’s test) especially in the responsive patients (0/4). EPP was associated with increased hemorrhagic events (100% vs. 8.3%, P<0.01, Fisher’s test) and prolonged length of ICU stay (median 7 vs. 3 days, P=0.02, Mann Whitney test). Overall 1- and 2-years recurrence rates were 6.7% and 26.7% respectively and patients after induction had lower recurrences at 2 years (12.5% vs. 42.9% in the non-induction group). Notably, none of the induction responsive patients but two of the EPP patients had their diseases relapsed during the follow-up time. CONCLUSIONS: Neoadjuvant chemotherapy seems to be a beneficial addition to surgery and adjuvant radiotherapy for stage IVa thymoma. EPP is a more traumatic procedure and whether it may bring any survival advantage is still debatable.
Biocompatibility and Oxidative Stability of Radiolucent Breast Implants (2000)

For more than 70 years Plastic and Reconstructive Surgery® has been the one consistently excellent reference for every specialist who uses plastic surgery techniques or works in conjunction with a plastic surgeon. The journal brings readers up-to-the-minute reports on the latest techniques and follow-up for maxillofacial reconstruction, burn repair, cosmetic reshaping, as well as news on medicolegal issues. The cosmetic section provides expanded coverage on new procedures and techniques.
A machine learning approach predicts future risk to suicidal ideation from social media data (2020)

Machine learning analysis of social media data represents a promising way to capture longitudinal environmental influences contributing to individual risk for suicidal thoughts and behaviors. Our objective was to generate an algorithm termed "Suicide Artificial Intelligence Prediction Heuristic (SAIPH)" capable of predicting future risk to suicidal thought by analyzing publicly available Twitter data. We trained a series of neural networks on Twitter data queried against suicide associated psychological constructs including burden, stress, loneliness, hopelessness, insomnia, depression, and anxiety. Using 512,526 tweets from <i>N</i> = 283 suicidal ideation (SI) cases and 3,518,494 tweets from 2655 controls, we then trained a random forest model using neural network outputs to predict binary SI status. The model predicted <i>N</i> = 830 SI events derived from an independent set of 277 suicidal ideators relative to <i>N</i> = 3159 control events in all non-SI individuals with an AUC of 0.88 (95% CI 0.86-0.90). Using an alternative approach, our model generates temporal prediction of risk such that peak occurrences above an individual specific threshold denote a ~7 fold increased risk for SI within the following 10 days (OR = 6.7 ± 1.1, <i>P</i> = 9 × 10<sup>-71</sup>). We validated our model using regionally obtained Twitter data and observed significant associations of algorithm SI scores with county-wide suicide death rates across 16 days in August and in October, 2019, most significantly in younger individuals. Algorithmic approaches like SAIPH have the potential to identify individual future SI risk and could be easily adapted as clinical decision tools aiding suicide screening and risk monitoring using available technologies.
Work-related stress in Her Majesty's Coastguard. (2011)

BACKGROUND. As a previously unresearched occupational group, the overall aim of this research was to establish the prevalence of stress and associated outcomes in Her Majesty's Coastguard (HMCG). MATERIAL AND METHODS. Data were collected from 282 coastguards by paper questionnaire and compared with general UK working population data from the Bristol Stress and Health at Work Study (SHAW) and the Psychosocial Working Conditions Survey (PWC), 2009. RESULTS. The level of high stress reported in HMCG (11%) was significantly lower than the comparison data (17%). The level of depression found was significantly higher. CONCLUSIONS. HMCG had lower levels of stress than the general UK working population, due, in part to high levels of social support. Data suggests HMCG worthy of study for both negative effects of stress and stress reduction elsewhere.
MANIC (2019)

Ultra-low-power sensor nodes enable many new applications and are becoming increasingly pervasive and important. Energy efficiency is the key determinant of the value of these devices: battery-powered nodes want their battery to last, and nodes that harvest energy should minimize their time spent recharging. Unfortunately, current devices are energy-inefficient.
A novel bacterial tyrosine kinase essential for cell division and differentiation (1999)

Protein kinases play central roles in the regulation of eukaryotic and prokaryotic cell growth, division, and differentiation. The Caulobacter crescentus divL gene encodes a novel bacterial tyrosine kinase essential for cell viability and division. Although the DivL protein is homologous to the ubiquitous bacterial histidine protein kinases (HPKs), it differs from previously studied members of this protein kinase family in that it contains a tyrosine residue (Tyr-550) in the conserved H-box instead of a histidine residue, which is the expected site of autophosphorylation. DivL is autophosphorylated on Tyr-550 in vitro, and this tyrosine residue is essential for cell viability and regulation of the cell division cycle. Purified DivL also catalyzes phosphorylation of CtrA and activates transcription in vitro of the cell cycle-regulated fliF promoter. Suppressor mutations in ctrA bypass the conditional cell division phenotype of cold-sensitive divL mutants, providing genetic evidence that DivL function in cell cycle and developmental regulation is mediated, at least in part, by the global response regulator CtrA. DivL is the only reported HPK homologue whose function has been shown to require autophosphorylation on a tyrosine, and, thus, it represents a new class of kinases within this superfamily of protein kinases.
What is the space of camera response functions? (2003)

Many vision applications require precise measurement of scene radiance. The function relating scene radiance to image brightness is called the camera response. We analyze the properties that all camera responses share. This allows us to find the constraints that any response function must satisfy. These constraints determine the theoretical space of all possible camera responses. We have collected a diverse database of real-world camera response functions (DoRF). Using this database we show that real-world responses occupy a small part of the theoretical space of all possible responses. We combine the constraints from our theoretical space with the data from DoRF to create a low-parameter Empirical Model of Response (EMoR). This response model allows us to accurately interpolate the complete response function of a camera from a small number of measurements obtained using a standard chart. We also show that the model can be used to accurately estimate the camera response from images of an arbitrary scene taken using different exposures. The DoRF database and the EMoR model can be downloaded at http://www.cs.columbia.edu/CAVE.
Chemokine Receptors in Neuroinflammation (2007)

Actions of chemokines and the interaction with specific receptors within the central nervous system (CNS) surpass their original defined role of leukocyte recruitment to inflamed tissues. Chemokine receptor expression by resident CNS cells is crucial for normal brain development and architectural organization, neuronal protection during inflammatory and neurotoxic challenges, and, among many others, protective mechanisms during inflammatory conditions such as multiple sclerosis. The chemokine/chemokine receptor systems involved in such significant functions include CXCR4/CXCL12, CXCR2/CXCL1, and CX3CR1/CX3CL1. In this chapter, we discuss how these receptors might contribute to modulate communication within the CNS and with peripheral elements, and we also suggest potential mechanisms of action of fractalkine and the translation of these into the understanding of microglial function during neuro-inflammatory conditions.
CONSERVATION OF CORRODED SILVER (1979)

A new treatment for the conservation of silver artifacts has been developed based on chemical reduction of the silver corrosion products to metallic silver. This reduction is achieved through the use of alkaline dithionite solutions in the absence of atmospheric oxygen. The method has been applied to silver artifacts recovered from shipwrecks but it should also be suitable for land site materials. The results obtained are superior to those using previous methods. As it is rapid, uses cheap readily available chemicals, and is well suited to bulk treatments, it also gives considerable cost and time benefits.
Buprenorphine Effects on Morphine- and Cocaine-Induced Subjective Responses by Drug-Dependent Men (1994)

The effects of daily buprenorphine treatment (4 or 8 mg/day, sublingual) on reports of subjective effects after single intravenous doses of morphine (10 mg), cocaine (30 mg), and saline placebo were studied on an inpatient clinical research ward in 26 men concurrently dependent on opioids and cocaine (DSM-III-R). Latency to detection and certainty of a drug effect, as well as drug quality (intensity, euphoria, and dysphoria), were studied before and after 10 to 12 days of buprenorphine maintenance. Saline was accurately identified by all 26 patients during the drugfree baseline and by 25 patients during buprenorphine maintenance conditions. All patients accurately identified morphine during the drugfree period before treatment with buprenorphine, but 18 (69%) of 26 patients were unable to detect morphine during buprenorphine maintenance and 2 misidentified morphine as cocaine. Six men (23%) accurately identified morphine and reported that the intensity and quality of morphine's effects were equivalent to drugfree conditions. Cocaine levels in plasma 5 minutes after intravenous cocaine injection were equivalent before and during buprenorphine treatment and averaged 282.8 +/- 43.6 and 295.2 +/- 28.8 ng/ml during 4 and 8 mg/day of buprenorphine maintenance, respectively. All patients accurately identified cocaine before and during buprenorphine maintenance, and there were no significant changes in latency to detection and certainty of a drug effect or reports of cocaine-induced intensity or euphoria during buprenorphine treatment. The concordance between responses to morphine and cocaine during inpatient buprenorphine maintenance and drug use during the first 4 weeks of outpatient buprenorphine treatment was also examined in 16 men. The effects of buprenorphine on individual responses to an acute intravenous dose of morphine or cocaine during the inpatient study did not reliably predict the frequency of heroin or cocaine self-administration during the first 4 weeks of daily outpatient buprenorphine maintenance.
Effects of the molecular structure of the interface and continuous phase on solubilization of water in water/oil microemulsions (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEffects of the molecular structure of the interface and continuous phase on solubilization of water in water/oil microemulsionsMean Jeng Hou and D. O. ShahCite this: Langmuir 1987, 3, 6, 1086–1096Publication Date (Print):November 1, 1987Publication History Published online1 May 2002Published inissue 1 November 1987https://doi.org/10.1021/la00078a036RIGHTS & PERMISSIONSArticle Views985Altmetric-Citations191LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (1 MB) Get e-Alerts Get e-Alerts
High Resolution of Plasmonic Resonance Scattering Imaging with Deep Learning (2022)

The dark-field microscopy (DFM) imaging technology has the advantage of a high signal-to-noise ratio, and it is often used for real-time monitoring of plasmonic resonance scattering and biological imaging at the single-nanoparticle level. Due to the limitation of the optical diffraction limit, it is still a challenging task to accurately distinguish two or more nanoparticles whose distance is less than the diffraction limit. Here, we propose a computational strategy based on a deep learning framework (NanoNet), which will realize the effective segmentation of the scattered light spots in diffraction-limited DFM images and obtain high-resolution plasmonic light scattering imaging. A small data set of DFM and the corresponding scanning electron microscopy (SEM) image pairs are used to learn for obtaining a highly resolved semantic imaging model using NanoNet, and thus highly resolved DFM images matching the resolution of those acquired using SEM can be obtained. Our method has the ability to transform diffraction-limited DFM images to highly resolved ones without adding a complex optical system. As a proof of concept, a highly resolved DFM image of living cells through the NanoNet technique is successfully made, opening up a new avenue for high-resolution optical nanoscopic imaging.
Ultralow-Noise SiN Trampoline Resonators for Sensing and Optomechanics (2016)

Accurately measuring extremely small forces is important in many fields of physics, materials science, and engineering. Researchers demonstrate tiny ``trampoline'' mechanical sensors that are exquisitely sensitive to attonewton forces at room temperature.
Dynamic software updating (2001)

Many important applications must run continuously and without interruption, yet must be changed to fix bugs or upgrade functionality. No prior general-purpose methodology for dynamic updating achieves a practical balance between flexibility, robustness, low overhead, and ease of use.
A generalized beamformer based on a spatial bispectrum (1993)

The bispectrum is the expected value of the third-order cumulant of the data sequence of a signal in either space or time. Much analysis based on the bispectrum has already been carried out in the time domain, where information regarding the stationarity, linearity, and Gaussianity of the signal series can be analyzed. In this paper, it is shown that these concepts can be directly applied to the spatial domain, resulting in a generalization of the standard k-ω beamformer. It is shown that the ability of the bispectrum to indicate nonstationarity in the data series allows this generalized beamformer to account for nonplanar aspects of the incoming signal wave front, thereby allowing for source localization in which bearing and range estimation evolve in a self-consistent framework. Thus bearing estimation and wave front curvature ranging appear as special cases. It is also shown that the technique is applicable to the analysis of more complicated propagation scenarios such as normal mode propagation.
Graphene controlled Brewster angle device for ultra broadband terahertz modulation (2018)

Terahertz modulators with high tunability of both intensity and phase are essential for effective control of electromagnetic properties. Due to the underlying physics behind existing approaches there is still a lack of broadband devices able to achieve deep modulation. Here, we demonstrate the effect of tunable Brewster angle controlled by graphene, and develop a highly-tunable solid-state graphene/quartz modulator based on this mechanism. The Brewster angle of the device can be tuned by varying the conductivity of the graphene through an electrical gate. In this way, we achieve near perfect intensity modulation with spectrally flat modulation depth of 99.3 to 99.9 percent and phase tunability of up to 140 degree in the frequency range from 0.5 to 1.6 THz. Different from using electromagnetic resonance effects (for example, metamaterials), this principle ensures that our device can operate in ultra-broadband. Thus it is an effective principle for terahertz modulation.
Identifying the optimum composition in organic solar cells comprising non-fullerene electron acceptors (2013)

We explore the inter-relationship between the phase behavior and photovoltaic performance for two blend systems comprising poly(3-n-hexylthiophene-2,5-diyl) (P3HT) as the electron donating moiety and two newly developed small molecule non-fullerene electron acceptors. Binary non-equilibrium temperature/composition phase diagrams of the two systems are prepared from differential scanning calorimetry (DSC) thermograms of blends of different compositions. The phase behavior is correlated with the optoelectronic performance of corresponding binaries in bulk heterojunction (BHJ) solar cells. The thermal and optoelectronic blend characterization is supported with optical microscopy and specular X-ray diffraction (sXRD) experiments. For both electron-accepting compounds the composition yielding the maximum photocurrent generation in devices was found to be in the hypoeutectic regime, i.e. at compositions that are shifted from the eutectic towards the small molecule rich region in the phase diagrams. We demonstrate that measuring the thermal properties of the blends is useful for rapid component ratio optimization and the evaluation of unexplored materials combinations.
Neck Tenderness As an Initial Presentation of Disseminated Aspergillosis; FNA Is an Option or a Must? (2014)

Asperillus thyroiditis (AT) has been considered for long time a postmortem diagnosis in immunocompromised patients. Disseminated disease is seen in the majority of patients. Diagnosis of AT during life needs high index of suspicion.
A generalized approach to block diagonalization for multiuser MIMO downlink (2010)

In multiple input multiple output (MIMO) systems, multiuser enhancement is in the implementation phase. Block diagonalization (BD) is known as the safest technique for the multiuser MIMO downlink since it suppresses the inter-user interference (IUI) perfectly. However, BD consumes most of the transmit antenna resource to form many nulls. Thus, it is very difficult to obtain the transmit diversity gain. In the paper, the adaptive selection of the number of layers is considered. Such approaches have been limited to iterative beamforming. Here, we formulate deterministic transmit beamforming as a generalized approach to the BD (GBD), based on a concept of projecting the IUI to a limited vector space. Our proposal can efficiently utilize the extra degrees of freedom, which are obtained in exchange for reducing the number of layers, to provide the diversity gain in the transmit beamforming. The high capability of the GBD is confirmed by computer simulations.
Amino acid depletion and appearance during porcine preimplantation embryo development in vitro (2005)

Preimplantation embryos can consume and produce amino acids in a manner dependent upon the stage of development that may be predictive of subsequent viability. In order to examine these relationships in the pig, patterns of net depletion and appearance of amino acids by in vitro produced porcine preimplantation embryos were examined. Cumulus oocyte complexes derived from slaughterhouse pre-pubertal pig ovaries were matured for 40 h in defined TCM-199 medium (containing PVA) before being fertilised (Day 0) with frozen-thawed semen in Tris-based medium. After 6 h, presumptive zygotes were denuded and cultured in groups of 20, in NCSU-23 medium modified to contain 0.1 mM glutamine plus a mixture of 19 amino acids (aa) at low concentrations (0.02-0.11 mM) (NCSU-23(aa)). Groups of 2-20 embryos were removed (dependent on stage) on Day 0 (1 cell), Day 1 (two- and four-cells), Day 4 (compact morulae) and Day 6 (blastocysts) and placed in 4 mul NCSU-23aa for 24 h. After incubation, the embryos were removed and the spent media was analysed by HPLC. The net rate of amino acid depletion or appearance varied according to amino acid (P < 0.001) and, apart from serine and histidine, stage of development (P < 0.014). Glycine, isoleucine, valine, phenylalanine, tryptophan, methionine, asparagine, lysine, glutamate and aspartate consistently appeared, whereas threonine, glutamine and arginine were consistently depleted. Five types of stage-dependent trends could be observed: Type I: amino acids having high rates of net appearance on Day 0 that reached a nadir on Day 1 or 4 but subsequently increased by Day 6 (glycine, glutamate); Type II: those that exhibited lower rates of net appearance on Days 0 and 6 compared with the intermediate Days 1 and 4 (isoleucine, valine, phenylalanine, methionine, arginine); Type III: amino acids which showed a continuous fall in net appearance (asparagine, aspartate); Type IV: those that exhibited a steady fall in net depletion from Day 0 to Day 6 (glutamine, threonine); Type V: those following no discernable trend. Analysis of further embryo types indicated that presumptive polyspermic embryos on Day 0 had increased (P < 0.05) net rates of leucine, isoleucine, valine and glutamate appearance, and reduced (P < 0.05) net rates of threonine and glutamine depletion compared with normally inseminated oocytes. These data suggest that the net rates of depletion and uptake of amino acids by pig embryos vary between a) amino acids, b) the day of embryo development and, c) the type of embryos present at a given stage of development. The results also suggested that the net depletion and appearance rates of amino acids by early pig embryos might be more similar to those of the human than those of the mouse and cow.