gebhart/patrepeval huggingface dataset:
Synthesis and cell attachment activity of bioactive oligopeptides: RGD, RGDS, RGDV, and RGDT (1991)

Tetrapeptides, Arg-Gly-Asp-Ser (RGDS), Arg-Gly-Asp-Val (RGDV), and Arg-Gly-Asp-Thr (RGDT), present in the cell-attachment domain of fibronectin, vitronectin, and collagen, respectively, were synthesized by using an improved liquid-phase procedure. Bioactivities of RGD and RGDX (X = S, V, and T) as cell recognition determinants were investigated by two methods to evaluate interactions of these oligopeptides with L-929 fibroblast cells originating in mouse epithelia. In the first method, these oligopeptides were immobilized to ethylene-acrylic acid copolymer (EAA) film, and the cell-attachment activity of the immobilized film was measured. In the second method, interaction of oligopeptides with the cells was evaluated by measuring the cell inhibition caused by oligopeptides. It was found that RGD and RGDX exhibit remarkable cell-attachment activity, and the activity of oligopeptides depends on X.
Self‐Healing Soft Sensors: Self‐Healing Soft Sensors: From Material Design to Implementation (Adv. Mater. 11/2021) (2021)

The emerging field of self-healing soft sensors is presented and discussed by Hossam Haick and co-workers in article number 2004190, also indicating pathways to be followed by material designers, synthetic chemists, and engineers. In addition, ways to facilitate the development of high-performance and durable sensing devices that can be easily integrated into real-life applications are scrutinized.
Low Cost Binary Proximity Sensor For Automotive Applications (1990)

A fiber optic binary position sensor has been fabricated simply and inexpensively. This sensor exploits the Faraday Effect to detect the presence of a piece of ferrrous metal The sensor is positioned inside a ring magnet, so that when a ferrous metal object passes close to the face of the magnet, it distorts the field, changing the output of the sensor from low optical power to high. The key component is a piece of bismuth doped iron garnet film with an extremely high Faraday Rotation per unit length and a low saturation magnetization. Material properties of this film will be discussed, along with sensor design and performance. This sensor has many potential applications in the automotive industry, such as monitoring door, hood and trunk positions.
Lung nodule classification utilizing support vector machines (2003)

Lung cancer is one of the deadly and most common diseases in the world. Radiologists fail to diagnose small pulmonary nodules in as many as 30% of positive cases. Many methods have been proposed in the literature such as neural network algorithms. Recently, support vector machines (SVMs) had received increasing attention for pattern recognition. The advantage of SVM lies in better modeling the recognition process. The objective of this paper is to apply support vector machines SVMs for classification of lung nodules. The SVM classifier is trained with features extracted from 30 nodule images and 20 non-nodule images, and is tested with features out of 16 nodule/non-nodule images. The sensitivity of SVM classifier is found to be 87.5%. We intend to automate the pre-processing detection process to further enhance the overall classification.
Allelic imbalance in mammary carcinomas induced by either 7,12‐dimethylbenz[a]anthracene or ionizing radiation in rats carrying genes conferring differential susceptibilities to mammary carcinogenesis (1996)

To identify and compare the genetic lesions associated with tumorigenesis in rats carrying the mammary carcinoma suppressor (MCS) 1 gene, we induced mammary carcinomas in (Wistar Furth (WF) × Copenhagen (Cop))F1 rats by using either 7,12-dimethylbenz[a]anthracene (DMBA) or radiation. The tumors were screened for allelic imbalances by using polymerase chain reaction and 65 polymorphic microsatellite markers spanning the genome. No allelic imbalance was detected at the mapped location of MCS-1 on chromosome 2; however, a scan of the genome revealed random allelic imbalances in the radiation-induced tumors. In addition, non-random loss of heterozygosity (LOH) on chromosome 1 in the DMBA-induced tumors was documented. We then screened three other subsets of DMBA- and radiation-induced mammary carcinomas from (WF × Fischer (F344))F1, (Wistar Kyoto×F344)F1, and (F344×Cop)F1 rats for imbalance on chromosomes 1 and 2. No allelic imbalance was detected in the MCS-1 region of chromosome 2 in any of the tumors screened. Nonrandom imbalance on chromosome 1 was detected but only in the DMBA-induced tumors from the (F344×Cop)F1 rats. Thus, only Cop-derived F1 rats have mammary tumors with the chromosome 1 imbalance; however, the imbalance does not favor the Cop parental allele. We also analyzed the DMBA-induced tumors with LOH at chromosome 1 for Ha-ras codon 61 mutation and found no association. These results suggest that loss of the MCS-1 Cop allele is not required for tumor formation, that the genetic background of the F1 rat appears to influence the type of genetic lesion identified in the mammary tumors, and that there is no association between Ha-ras codon 61 mutation and chromosome 1 imbalance in our model system. © 1996 Wiley-Liss, Inc.
Utility of Whole-Genome Sequencing in Characterizing Acinetobacter Epidemiology and Analyzing Hospital Outbreaks (2015)

Acinetobacter baumannii frequently causes nosocomial infections and outbreaks. Whole-genome sequencing (WGS) is a promising technique for strain typing and outbreak investigations. We compared the performance of conventional methods with WGS for strain typing clinical Acinetobacter isolates and analyzing a carbapenem-resistant A. baumannii (CRAB) outbreak. We performed two band-based typing techniques (pulsed-field gel electrophoresis and repetitive extragenic palindromic-PCR), multilocus sequence type (MLST) analysis, and WGS on 148 Acinetobacter calcoaceticus-A. baumannii complex bloodstream isolates collected from a single hospital from 2005 to 2012. Phylogenetic trees inferred from core-genome single nucleotide polymorphisms (SNPs) confirmed three Acinetobacter species within this collection. Four major A. baumannii clonal lineages (as defined by MLST) circulated during the study, three of which are globally distributed and one of which is novel. WGS indicated that a threshold of 2,500 core SNPs accurately distinguished A. baumannii isolates from different clonal lineages. The band-based techniques performed poorly in assigning isolates to clonal lineages and exhibited little agreement with sequence-based techniques. After applying WGS to a CRAB outbreak that occurred during the study, we identified a threshold of 2.5 core SNPs that distinguished nonoutbreak from outbreak strains. WGS was more discriminatory than the band-based techniques and was used to construct a more accurate transmission map that resolved many of the plausible transmission routes suggested by epidemiologic links. Our study demonstrates that WGS is superior to conventional techniques for A. baumannii strain typing and outbreak analysis. These findings support the incorporation of WGS into health care infection prevention efforts.
Rate dependence of electrical and mechanical properties of conductive polymer nanocomposites (2015)

Conductive polymer nanocomposites with enhanced electrical and thermal properties show promise as an alternative solution for electronic materials. For example, electronic interconnect materials will have comparable electrical and thermal conductivity to solder with an increased operating range of strain and temperature. This paper documents the fabrication and experimental evaluation of a prototype conductive polymer nanocomposite. Material selection, fabrication processes, and initial characterization of a low Tg polymer with a high fill ratio of carbon nanotubes is presented. The electrical and thermal properties of the composite are measured and compared with predictions. The mechanical properties are measured using dynamic mechanical analysis (DMA) over a wide temperature range. The mechanical and electrical responses of the conductive polymer composite are simultaneously measured at higher strain rates using a modified split Hopkinson pressure bar (SHPB) apparatus. The dynamic stress-strain response is obtained using traditional analytic methods (e.g., two- and three-wave analysis). The electrical response is observed using constant current excitation with high bandwidth (>500 kHz) instrumentation. The dynamic compression data implies the change in electrical resistance is solely a function of the material deformation, i.e., the material exhibits constant electrical conductivity and is insensitive to the applied loads. DMA and SHPB dynamic data are used to estimate the parameters in a Mulliken-Boyce constitutive model, and the resulting behavior is critically evaluated. Finally, progress towards improving the polymer composite's mechanical, electrical, and thermal properties are discussed.
Simple scheme for creation of persistent optical event horizons (2020)

We demonstrate numerically and experimentally a simple scheme for self-generation of a highly efficient and long-lasting fiber optical event horizon which requires only standard equipment in an optical laboratory.
Effect of the BRCA2 CTRD domain on RAD51 filaments analyzed by an ensemble of single molecule techniques (2011)

Homologous recombination is essential for the preservation of genome stability, thereby preventing cancer. The recombination protein RAD51 drives DNA strand exchange, which requires the assembly, rearrangement and disassembly of a RAD51 filament on DNA, coupled to ATP binding and hydrolysis. This process is facilitated and controlled by recombination mediators and accessory factors. Here, we have employed a range of single molecule techniques to determine the influence of the C-terminal RAD51 interaction domain (CTRD) of the breast cancer tumor suppressor BRCA2 on intrinsic aspects of RAD51-DNA interactions. We show that at high concentration the CTRD entangles RAD51 filaments and reduces RAD51 filament formation in a concentration dependent manner. It does not affect the rate of filament disassembly measured as the loss of fluorescent signal due to intrinsic RAD51 protein dissociation from double-stranded DNA (dsDNA). We conclude that, outside the context of the full-length protein, the CTRD does not reduce RAD51 dissociation kinetics, but instead hinders filament formation on dsDNA. The CTRDs mode of action is most likely sequestration of multiple RAD51 molecules thereby rendering them inactive for filament formation on dsDNA.
Image retrieval by hypertext links (1997)

article Free Access Share on Image retrieval by hypertext links Authors: V. Harmandas Computing Science, University of Glasgow, Glasgow G12 8QQ, Scotland Computing Science, University of Glasgow, Glasgow G12 8QQ, ScotlandView Profile , M. Sanderson Computing Science, University of Glasgow, Glasgow G12 8QQ, Scotland Computing Science, University of Glasgow, Glasgow G12 8QQ, ScotlandView Profile , M. D. Dunlop Computing Science, University of Glasgow, Glasgow G12 8QQ, Scotland Computing Science, University of Glasgow, Glasgow G12 8QQ, ScotlandView Profile Authors Info & Claims ACM SIGIR ForumVolume 31Issue SIDecember 1997 pp 296–303https://doi.org/10.1145/278459.258594Published:01 July 1997Publication History 51citation701DownloadsMetricsTotal Citations51Total Downloads701Last 12 Months11Last 6 weeks2 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my Alerts New Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
UV‐Activated Luminescence/Colourimetric O2 Indicator (2008)

An oxygen indicator is described, comprising nanoparticles of titania dispersed in hydroxyethyl cellulose (HEC) polymer film containing a sacrificial electron donor, glycerol, and the redox indicator, indigo‐tetrasulfonate (ITS). The indicator is blue‐ coloured in the absence of UV light, however upon exposure to UV light it not only loses its colour but also luminesces, unless and until it is exposed to oxygen, whereupon its original colour is restored. The initial photobleaching spectral (absorbance and luminescence) response characteristics in air and in vacuum are described and discussed in terms of a simple reaction scheme involving UV activation of the titania photocatalyst particles, which are used to reduce the redox dye, ITS, to its leuco form, whilst simultaneously oxidising the glycerol to glyceraldehye. The response characteristics of the activated, that is, UV photobleached, form of the indicator to oxygen are also reported and the possible uses of such an indicator to measure ambient O 2 levels are discussed.
Event-driven Video Deblurring via Spatio-Temporal Relation-Aware Network (2022)

Video deblurring with event information has attracted considerable attention. To help deblur each frame, existing methods usually compress a specific event sequence into a feature tensor with the same size as the corresponding video. However, this strategy neither considers the pixel-level spatial brightness changes nor the temporal correlation between events at each time step, resulting in insufficient use of spatio-temporal information. To address this issue, we propose a new Spatio-Temporal Relation-Attention network (STRA), for the specific event-based video deblurring. Concretely, to utilize spatial consistency between the frame and event, we model the brightness changes as an extra prior to aware blurring contexts in each frame; to record temporal relationship among different events, we develop a temporal memory block to restore long-range dependencies of event sequences continuously. In this way, the complementary information contained in the events and frames, as well as the correlation of neighboring events, can be fully utilized to recover spatial texture from events constantly. Experiments show that our STRA significantly outperforms several competing methods, e.g., on the HQF dataset, our network achieves up to 1.3 dB in terms of PSNR over the most advanced method. The code is available at https://github.com/Chengzhi-Cao/STRA.
Hemostatic characteristics of thawed, pooled cryoprecipitate stored for 35 days at refrigerated and room temperatures (2019)

The fibrinogen concentration and function of cryoprecipitate at extended storage durations are adequate for fibrinogen replacement in critical bleeding. These results support extension of the shelf life of cryoprecipitate when used for fibrinogen replacement.
Proteomic Analysis of Urothelium of Rats with Detrusor Overactivity Induced by Bladder Outlet Obstruction (2018)

<i>O</i>ver<i>a</i>ctive <i>b</i>ladder (OAB) syndrome is a condition that has four symptoms: urgency, urinary frequency, nocturia, and urge incontinence and negatively affects a patient's life. Recently, it is considered that the urinary bladder urothelium is closely linked to pathogenesis of OAB. However, the mechanisms of pathogenesis of OAB at the molecular level remain poorly understood, mainly because of lack of modern molecular analysis. The goal of this study is to identify a potential target protein that could act as a predictive factor for effective diagnosis and aid in the development of therapeutic strategies for the treatment of OAB syndrome. We produced OAB in a rat model and performed the first proteomic analysis on the mucosal layer (urothelium) of the bladders of sham control and OAB rats. The resulting data revealed the differential expression of 355 proteins in the bladder urothelium of OAB rats compared with sham subjects. Signaling pathway analysis revealed that the differentially expressed proteins were mainly involved in the inflammatory response and apoptosis. Our findings suggest a new target for accurate diagnosis of OAB that can provide essential information for the development of drug treatment strategies as well as establish criteria for screening patients in the clinical environment.
Cross-platform comparison of immune-related gene expression to assess intratumor immune responses following cancer immunotherapy (2021)

Neoadjuvant immunotherapy can induce immune responses within the tumor microenvironment. Gene expression can be used to assess responses with limited amounts of conventionally-fixed patient-derived samples. We aim to assess the cross-platform concordance of immune-related gene expression data. We performed comparisons across three panels in two platforms: Nanostring nCounter® PanCancer Immune Profiling Panel (nS), HTG EdgeSeq Oncology Biomarker Panel (HTG OBP) and Precision Immuno-Oncology Panel (HTG PIP). All tissue samples of 14 neoadjuvant GM-CSF treated, 14 neoadjuvant Provenge treated, and 12 untreated prostate cancer patients were radical prostatectomy (RP) tissues, while 6 prostatitis patients and 6 non-prostatitis subjects were biopsies. For all 52 patients, more than 90% of the common genes were significantly correlated (p < 0.05) and more than 76% of the common genes were highly correlated (r > 0.5) between any two panels. Co-inertia analysis also demonstrated high overall dataset structure similarity (correlation>0.84). Although both dimensionality reduction visualization analysis and unsupervised hierarchical cluster analysis for highly correlated common genes (r > 0.9) suggested a high-level of consistency across the panels, there were subsets of genes that were differentially expressed across the panels. In addition, while the effect size of the differential testing for neoadjuvant treated vs. untreated localized prostate cancer patients across the panels were significantly correlated, some genes were only differentially expressed in the HTG panels. Finally, the HTG PIP panel had the best classification performance among the 3 panels. These differences detected may be a result of the different panels or platforms due to their technical setting and focus. Thus, researchers should be aware of those potential differences when deciding which platform and panel to use.
The Oxidation of Captive Oxalate (1960)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Oxidation of Captive OxalatePatricia Saffir and Henry TaubeCite this: J. Am. Chem. Soc. 1960, 82, 1, 13–14Publication Date (Print):January 1, 1960Publication History Published online1 May 2002Published inissue 1 January 1960https://doi.org/10.1021/ja01486a004RIGHTS & PERMISSIONSArticle Views127Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (265 KB) Get e-Alerts Get e-Alerts
ChemInform Abstract: Imidazolylidenes, Imidazolinylidenes and Imidazolidines. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Detection of electronic counterfeit components (2015)

In this paper, the necessity and key questions for detection of counterfeit components is being described. Main goal is to inform professionals from academic as well as from industry sector how to detect counterfeit parts and be confident with evaluation. For these purposes some standard and some more specific methods are described more in detail. Also practical examples for counterfeit components detection like switching power transistor and bulk-capacitor (electrolytic capacitor) are given as well.
Glare and halo with refractive correction (2007)

Contact lens and unclean spectacle wearers both have significantly larger halos than emmetropes and those wearing cleaned spectacle lenses. Unclean spectacles may affect the accuracy of results in psychophysical and clinical testing.
Objective Evaluation of Exciting Engine Sound in Passenger Compartment During Acceleration (2000)

&lt;div class="htmlview paragraph"&gt;This paper describes an objective evaluation method for the engine sound quality in a car interior during acceleration. Two principal factors, pleasantness and raciness, of the engine sound quality were found with a subjective evaluation test in a laboratory. Psycho-acoustic indexes corresponding to these factors were revealed by investigating the correlation among subjective ratings and acoustic characteristics. The index of raciness was originally proposed for the assessment of sound that makes driving fun when the sound is emphasized. We propose that the design of engine sound is required with consideration of the balance between pleasantness and raciness.&lt;/div&gt;
Adsorption of SO2 on Bituminous Coal Char and Activated Carbon Fiber (1997)

The SO2 adsorption behaviors of activated carbons produced from Illinois coal and of commercially prepared activated carbon fibers (ACFs) were compared. There was no relation between surface area of coal-based carbons and SO2 adsorption, whereas adsorption of SO2 on the series of ACFs was inversely proportional to N2 BET surface area. Higher surface area ACFs had wider pores and adsorbed less SO2; thus, pore size distribution is thought to play a significant role in SO2 adsorption for these materials. Oxidation with HNO3 and/or H2SO4, followed by heat treatment at 700−925 °C to remove carbon−oxygen complexes, resulted in increased SO2 adsorption for both coal chars and ACFs. This behavior was explained by an increase in the available number of free sites, previously occupied by oxygen and now available for SO2 adsorption. The use of nitrogen-containing functional groups on ACFs of proper pore size shows promise for further increasing SO2 adsorption capacities. Knowledge of the relationship among the number of free sites, pore size, and surface chemistry on corresponding SO2 adsorption should lead to the development of more efficient adsorbents prepared from either coal or ACFs.
State of the art: Admission control and mobility management in heterogeneous wireless networks (2003)

Future mobile networks will not consist simply of one radio access technology such as WCDMA (wideband code division multiple access) or EDGE (enhanced data rate for GSM evolution), but will contain many different technologies. Seamless intersystem roaming across heterogeneous networks, as depicted in Figure 1, will be one of the main features in future generation mobile networks such as