gebhart/patrepeval huggingface dataset:
MobiShop: A secure Proximity based Social Networking application for the mall of Mauritius (2017)

Based on the proliferation of smartphones, a new type of social networking called Proximity based Social Networking (PBSN) was emerged based on the geo-locations of users in the vicinity. However, many concerns have been reported recently on PBSN applications where user information is intercepted and misused, specifically locations of users which are sensitive data. In this paper, a secure PBSN application called MobiShop has been designed and implemented for the largest shopping mall in Mauritius. Users can receive advertisements or coupons from shops when they are approaching those shops, buy cinema tickets and place orders in the food court using the MobiShop application. The payment is then done directly at the counters when they receive their tickets or food by using a transaction ID. Different security measures have been integrated in the application to secure the information and communication of the users. The AllJoyn framework is used to implement the discovery process and the chat system. All messages exchanged are encrypted using the RSA cryptographic algorithm and the passwords of the users are encrypted using the SHA-512 Hash algorithm. Evaluation tests have shown that MobiShop offers a secure platform for the Mauritian shoppers where integrity of the system is ensured and attacks such as man-in-the-middle attacks are prevented.
Direct stimulation by purified GM-CSF of the proliferation of multipotential and erythroid precursor cells (1980)

GM-CSF, purified from mouse lung-conditioned medium, stimulated granulocyte-macrophage colony formation but was unable to stimulate the formation of any type of pure or mixed erythroid colony in agar cultures of 12-day CBA fetal liver cells. However, initial incubation of cells for 2 days with purified GM-CSF, followed by addition of mouse spleen-conditioned medium (SCM), allowed the formation of up to 50% of the erythroid or mixed hemopoietic colonies expected in cultures stimulated from the outset by SCM. These GM-CSF-responsive colony-forming cells were not distinguishable from the remainder of cells forming erythroid or mixed colonies by sedimentation velocity or cell cycle status. From 302 clones stimulated to proliferate by purified GM-CSF, 25 formed erythroid or mixed hemopoietic colonies on transfer to cultures containing SCM. Clones initiated by SCM were unable to form erythroid or mixed colonies when transferred to cultures containing purified GM-CSF. Single cells from 12-day CBA fetal peripheral blood also were stimulated to proliferate by purified GM-CSF and subsequently formed pure or mixed erythroid colonies when SCM was added. GM-CSF is thus able to directly stimulate up to 5 cell divisions of at least 50% of detectable multipotential and early erythroid precursor cells.
Time and Modernity in the Mediterranean: A Case Study from Languedoc (2002)

This article develops a critical perspective on 'modernity', derived from an interest in the anthropology of time.Drawing on social scientific and philosophical work on time and temporality, I seek to unravel the temporal dimension of this term, both through an initial theoretical analysis and subsequent ethnographic interrogation.The ethnographic component of the article draws on a year's fieldwork in Monadires, a village near Narbonne, in Languedoc, France.Through a number of studies highlighting the changing temporalities of people's lives, the concept's utility is examined, and its relevance for discussion of the wider Mediterranean basin, and elsewhere, is brought out.The article concludes that for the notion of 'modernity' to retain critical utility, it must encompass a more precise appreciation of the temporal and contingent ethnographic features of social life.
Dual-Pulse CS-CELP: a toll-quality low-complexity speech coder at 7.8 kbit/s (2002)

Low-cost highly-efficient speech coding is important for personal multimedia communications. In this paper we propose a new low-complexity speech coding method called "Dual-Pulse CS-CELP (DP-CS-CELP)" at 7.8 kbit/s. This method is based on ITU-T G.729. To reduce the complexity, we applied a new excitation model to the random code vectors and simplified the LPC coding, adaptive codebook search, perceptual weighting, and the other structures. The number of operations for this encoder is 3.80 MOPS, which achieves real-time speech coding and decoding on personal computers. Although the efficiency of this coder is a little lower than that of G.729, the MOS listening test showed that the subjective quality was equivalent to or a little better than that of G.726 (32-kbit/s ADPCM).
The Application of Ion Beam Analysis to Mass Transport Studies in Mixed Electronic Ionic Conducting Electrodes (2013)

The measurement of the mass transport and oxygen exchange in materials for SOFCs has been greatly aided by the use of ion beam analysis techniques. In particular this has focused on the use of Secondary Ion Mass Spectrometry (SIMS) to measure diffusion profiles of oxygen 18 in ceramics to determine the kinetics of the bulk transport of oxygen. A second ion beam technique, Low Energy Ion Scattering (LEIS) can provide important information about the composition of the outermost atomic layers of the same materials where the gas/solid oxygen exchange process is taking place. The application of the newer technique of LEIS to materials for air electrodes is discussed and the behaviour of some common perovskite materials is explored.
Concepción y diseño de un programa de doctorado en ciencias médicas según el contexto local (2021)

Fundamento: los diseños curriculares posuniversitarios responden a elevadas exigencias en la formación académica como formas concretas del encargo social a las instituciones de educación superior en cada país. Objetivo: argumentar conceptos e ideas sobre la concepción y diseño del programa de doctorado en "Ciencias básicas como fundamento de las clínicas médicas”. Métodos: se realizó una revisión bibliográfica y documental que incluyó 32 fuentes entre leyes, resoluciones, reglamentos, indicaciones, instrucciones, artículos originales y artículos de revisión. Se seleccionaron 25, teniendo en cuenta su pertinencia y actualización según objetivo del trabajo. La búsqueda digital se realizó en SciELO, Google Académico e Infomed. Resultados: se identificaron conceptos y categorías fundamentales en la concepción y diseño de programas doctorales, se reconocieron ideas principales en la formación de un núcleo central de diseño, se logró una integración consecuente entre normativas nacionales vigentes y particularidades de la universidad de ciencias médicas como institución autorizada para la formación doctoral. Conclusiones: el programa de doctorado en “Ciencias básicas como fundamento de las clínicas médicas” mediante la interacción efectiva entre las normativas establecidas, diferentes argumentaciones teóricas encontradas en la literatura, las tradiciones y condiciones contextuales de la Universidad de Ciencias Médicas de Villa Clara, sin afectar el rigor, la originalidad y la pertinencia social. Se reconoció lo local como necesidad para la descentralización deseada y como expresión de compromiso y autonomía universitaria; en la que se manifiesta una posición profesional y ética ante los riesgos de formulaciones muy centralizadas y uniformes como posibles limitaciones en los procesos formativos.
Can the United States Be a Party to Binding Arbitration - The Constitutional Issues Re-Evaluated - Tenaska Washington Partners II v. The United States (1996)

It has long been assumed that the Constitution prohibited the United States government from entering binding arbitration as a party. The Department of Justice recently re-examined the issue and concluded that there is no absolute constitutional bar to government participation in binding arbitration.' Tenaska is the first reported court decision to adopt the Department of Justice's new reasoning. The court in Tenaska Washington Partners II v. The United States held that a dispute between a private party and a governmental agency must be submitted to binding arbitration when the parties' voluntary agreement contains an arbitration clause.'
DEVELOPMENT OF AMPEROMETRIC BIOSENSOR BASED ON LACTATE OXIDASE FOR LACTATE DETERMINATION (2016)

The amperometric biosensor was developed for determination of lactate concentration. As a bioselective element we used the enzyme lactate oxidase, coimmobilized with bovine serum albumin on the surface of amperometric transducer by glutaraldehyde covalent crosslinking. The platinum disc electrodes (Ø = 500 µm) served as transducers. The developed biosensor was highly sensitive to lactate, with a minimum limit of determination of lactate concentrations 3 µM and linear range 5 µM to 300-350 mM. It was shown that the proposed biosensor was characterized by high response replicability during several hours of non-stop measurement (the accuracy of measurement RSD = 3.4%) and satisfactory operational stability for several days. Optimal conditions for biosensor storage were analyzed and defined. One-month storage in the buffer solution at + 4 °C resulted in less than 50% loss of the biosensor activity. The impact of parameters of buffer solution (capacity and ionic strength) on the biosensor operation was analyzed. It was shown that the developed biosensor based on lactateoxidase used can successfully be used for lactate analysis in real biological liquids
Analysis of online information available for treatment of depression (2019)

Abstract The Internet has become a prime source of health information available to the public. Our aims were to assess the content and quality of online information for the treatment of depression. We searched, “How to cure depression” on Google and analysed the first 200 websites according to the website typology and a standard health information assessment tool, the Journal of the American Medical Association (JAMA) criteria (presence of authorship, date, disclosure, and references). We also analyzed content in terms of treatments mentioned and developed a Quality Indicator Score (QIS) based on the guidelines for treating depression from the UK National Institute for Health and Care Excellence (NICE). News websites were the most frequent typology followed by health portals, non-profit, professional and government; commercial websites were the least represented. In the top ten websites, news and health portals remained first and second respectively. Antidepressants were the most mentioned treatment, followed by psychotherapy, lifestyle &amp; exercise, social support, diet. The least mentioned interventions were sunlight &amp; light therapy, routine, and ketamine &amp; psychedelics. Commercial websites preferentially mentioned supplements, while ketamine and psychedelic drugs were the most covered by news outlets. Analysing webpages according to our QIS showed the median of NICE recommended treatments was 2.5 out of 5 possible treatments: antidepressants, lifestyle &amp; exercise, psychotherapy, social support and ECT. Government websites had the highest QIS, news and commercial websites the lowest. Webpages with high QIS ranked higher in Google.
The Wheat Peptidyl Prolylcis-trans-Isomerase FKBP77 Is Heat Induced and Developmentally Regulated1 (1999)

We isolated a cDNA encoding a 568-amino acid, heat-stress-induced peptidyl prolyl isomerase belonging to the FK506-binding-protein (FKBP) family. The open reading frame encodes for a peptidyl prolyl isomerase that possesses three FKBP-12-like domains, a putative tetratricopeptide motif, and a calmodulin-binding domain. Specific antibodies showed that the open reading frame encodes a heat-induced 77-kD protein, the wheat FKBP77 (wFKBP77), which exhibits 84% identity with the wFKBP73 and 42% identity with the human FKBP59. Because of the high similarity in sequence to wFKBP73, wFKBP77 was designated as the heat-induced isoform. The wFKBP77 mRNA steady-state level was 14-fold higher at 37 degreesC than at 25 degreesC. The wFKBP77 transcript abundance was the highest in mature embryos that had imbibed and 2-d-old green shoots exposed to 37 degreesC, and decreased to 6% in 6-d-old green shoots. The transcript level returned to the level detected at 25 degreesC after recovery of the embryos for 90 min at 25 degreesC. We compared wFKBP73 and wFKBP77 with the heat-shock proteins having cognate and heat-stress-induced counterparts.
Benfluorex: the last chapter of drug-induced valvular heart disease? (2010)

This editorial refers to ‘Valvular heart disease associated with benfluorex therapy: results from the French multicenter registry’ by F.L. Ven et al ., doi:10.1093/ejechocard/jeq172 .

The first case reports about drug-induced valvular heart disease (VHD) date from the 1960s with the use of ergot-derived drugs (methysergide and ergotamine) for the treatment of migraine.1 Nevertheless, public awareness about this particular entity came after the withdrawal of the appetite suppressant fenfluramine (Fen-Phen) in 1997.2 Thereafter a limited number of drugs have been added to this list such as pergolide, cabergoline, and MDMA (the main component of Ecstasy).3–5 The hallmark feature of these drugs or their metabolites is serotonin 2B (5-HT2B) receptor overstimulation, with valvular fibroblast proliferation and production of myxoid substance as a consequence.6 This leads to reduced leaflet mobility (restrictive VHD) due to superficial plaque like thickening of the valvular leaflets and subvalvular apparatus. Both …
Metaplastic ossification in the cartilage of the bronchus of a patient with chronic multi-drug resistant tuberculosis: a case report (2010)

Chronic inflammation in the lungs of our patient, caused by underlying tuberculosis, probably played a role in the development of osseous metaplasia from the associated cartilage of the bronchial wall.
Identifying loci for behavioral traits using genome‐tagged mice (2003)

Abstract Identification of behavioral loci through complex trait mapping remains a widely employed approach but suffers from poor gene localization and low replicability. Genome‐tagged mice (GTMs) are overlapping sets of congenic strains spanning the whole genome and offer the possibilities of superior mapping power and reproducibility. In this study, three GTM strains each consisting of an average ∼27 cM DBA/2J genomic intervals introgressed onto a C57BL/6J background were employed for localization of behavioral traits. These GTMs were chosen because the corresponding chromosomal regions had been previously identified as containing loci for learning and memory. Analysis of the GTMs allowed confirmation of the learning and memory loci, and one on chromosome 3 was in addition fine mapped to an 8.8‐cM region of overlap between two of the GTMs. Moreover, loci for prepulse inhibition of the startle response, acoustic startle response, and spontaneous locomotor activity were also mapped. These results suggest that the GTMs should be a valuable resource for mapping and confirmation of loci contributing to complex behavioral traits in the mouse. © 2003 Wiley‐Liss, Inc.
Identifying Repair Targets in Action Control Dialogue. (2006)

This paper proposes a method for dealing with repairs in action control dialogue to resolve participants’ misunderstanding. The proposed method identifies the repair target based on common grounding rather than surface expressions. We extend Traum’s grounding act model by introducing degree of groundedness, and partial and mid-discourse unit grounding. This paper contributes to achieving more natural human-machine dialogue and instantaneous and flexible control of agents.
Very low bit rate video coding using vector-based techniques (2002)

This paper reports the advances of using vector-based techniques for very low bit rate video coding. High efficiency has been achieved for coding intraframes (the first frame and subsequent refreshing key frames) and motion compensated difference frames of a video sequence. A video frame (I or P frame) is first decomposed into a set of vector bands using a vector wavelet transform. Adaptive lattice vector quantization is then used in the vector bands. A 100% labeling efficiency is achieved for lattice vector quantization by using a set of generalized labeling algorithms for various important lattices with pyramid and sphere boundaries. An adaptive algorithm is used to determine the type of lattice vector quantisation according to the statistical distribution of the vectors in the vector wavelet domain. Finally, entropy coding is used to code the indexes generated from lattice vector quantization. Our coding results show that a gain of 3 to 8 dBs in PSNR for intraframe coding can be achieved at a bitrate level of 16 Kbpf over H.263. Subjective quality improvement of the proposed algorithm over H.263 can be observed.
COVID-19 vaccine supply chain management: a US perspective (2022)

The COVID-19 pandemic has had a dramatic impact on vaccine industry supply chains. Reliance on just-in-time supply chains and limited capacity posed challenges for vaccine manufacturers as they rapidly and dramatically scaled-up production. Supply chain management and expansion are as important as vaccine development itself, and here we outline how the US Government has worked with multiple stakeholders to support supply chains and maximize ‘shots in arms’ – and what is needed to ensure we are better prepared for future outbreaks.
Co-nonsolvency of PNiPAM at the transition between solvation mechanisms (2014)

We investigate the co-nonsolvency of poly-N-isopropyl acrylamide (PNiPAM) in different water-alcohol mixtures and show that this phenomenon is due to two distinct solvation contributions governing the phase behavior of PNiPAM in the water-rich and alcohol-rich regime respectively. While hydrophobic hydration is the predominant contribution governing the phase behavior of PNiPAM in the water-rich regime, the mixing contributions governing the phase behavior of classical polymer solutions determine the phase behavior of PNiPAM in the alcohol-rich regime. This is evidenced by distinct scaling relations denoting the energetic state of the aqueous medium as a key parameter for the phase behavior of PNiPAM in the water-rich regime, while the volume fractions of respectively water, alcohol and PNiPAM become relevant parameters in the alcohol-rich regime. Adding alcohol to water decreases the energetics of the aqueous medium, which gradually suppresses hydrophobic hydration, while adding water to alcohol decreases the solvent quality. Consequently, PNiPAM is insoluble in the intermediate range of solvent composition, where neither hydrophobic hydration nor the mixing contributions prevail. This accounts for the co-nonsolvency phenomenon observed for PNiPAM in water-alcohol mixtures.
Design of distributed examination system based on task (2011)

To solve the bottleneck problem that occurred when traditional examination systems used in large-scale test,a distributed test design pattern is proposed.By genetic algorithm,the whole test task would automatically be divided into smaller parts and each part would be distributed to the test servers in a distributed deployment,in parallel to provide examination services.It can both effectively solve the network bandwidth,the processor capacity,database access and other bottlenecks,and meet the requirements of distributed real-time and rationality.Finally,the design is validated by practical application.
Spatial Network Mapping of Pulmonary Multidrug-Resistant Tuberculosis Cavities Using RNA Sequencing (2019)

<b>Rationale:</b> There is poor understanding about protective immunity and the pathogenesis of cavitation in patients with tuberculosis.<b>Objectives:</b> To map pathophysiological pathways at anatomically distinct positions within the human tuberculosis cavity.<b>Methods:</b> Biopsies were obtained from eight predetermined locations within lung cavities of patients with multidrug-resistant tuberculosis undergoing therapeutic surgical resection (<i>n</i> = 14) and healthy lung tissue from control subjects without tuberculosis (<i>n</i> = 10). RNA sequencing, immunohistochemistry, and bacterial load determination were performed at each cavity position. Differentially expressed genes were normalized to control subjects without tuberculosis, and ontologically mapped to identify a spatially compartmentalized pathophysiological map of the cavity. <i>In silico</i> perturbation using a novel distance-dependent dynamical sink model was used to investigate interactions between immune networks and bacterial burden, and to integrate these identified pathways.<b>Measurements and Main Results:</b> The median (range) lung cavity volume on positron emission tomography/computed tomography scans was 50 cm<sup>3</sup> (15-389 cm<sup>3</sup>). RNA sequence reads (31% splice variants) mapped to 19,049 annotated human genes. Multiple proinflammatory pathways were upregulated in the cavity wall, whereas a downregulation "sink" in the central caseum-fluid interface characterized 53% of pathways including neuroendocrine signaling, calcium signaling, triggering receptor expressed on myeloid cells-1, reactive oxygen and nitrogen species production, retinoic acid-mediated apoptosis, and RIG-I-like receptor signaling. The mathematical model demonstrated that neuroendocrine, protein kinase C-θ, and triggering receptor expressed on myeloid cells-1 pathways, and macrophage and neutrophil numbers, had the highest correlation with bacterial burden (<i>r</i> > 0.6), whereas T-helper effector systems did not.<b>Conclusions:</b> These data provide novel insights into host immunity to <i>Mycobacterium tuberculosis</i>-related cavitation. The pathways defined may serve as useful targets for the design of host-directed therapies, and transmission prevention interventions.
Effects of diclofenac on lithium kinetics (1981)

The influence of the prostaglandin (PG) synthesis-inhibiting, nonsteroidal anti-inflammatory drug (NSAID) diclofenac on lithium kinetics was studied in five normal women on a 150-mEq sodium diet. Diclofenac decreased lithium renal clearance by 23% (P - 0.002) and increased lithium plasma levels by 26% (P - 0.001). Renal PG synthesis was suppressed by 53% of control values. These data show a clinically important drug interaction, possibly on the basis of a PG-dependent mechanism, with the risk of lithium intoxication for patients treated with lithium salts and NSAIDs.
Distinction Between Streamer to Glow Transition in Atmospheric Discharge using Optical Emission Spectroscopy (2005)

Summary form only given. Generally to generate glow discharge in air, sufficient numbers of seed electrons or metastables are needed. But by electronegative gases such as oxygen and water vapor etc, atmospheric discharge exists as streamer, non-uniform microdischarges. As mentioned by other references, the parameter Ptimesd in dielectric barrier discharge (DBD) controls electrical breakdown. At high gas pressure, two types of breakdown mechanisms can occur. One is called Townsend breakdown at low Ptimesd and the other breakdown is termed streamer breakdown at high Ptimesd. Therefore, we investigated optimum streamer-to-glow transition Ptimesd by controlling pressure. And to find transition Ptimesd condition, we compared the relative intensities of generated species at each discharge mode during discharge by optical emission spectroscopy analysis. Experimental results show that in case of DBD using alumina with 1 mm thickness streamer-to-glow transition occurred at the 1 torrmiddotcm condition.