gebhart/patrepeval huggingface dataset:
Prediction of Automotive Hydrobushing Resonant Frequency (1999)

Abstract The success of hydromounts in vehicle vibration isolation during the past decade and a half has stimulated automotive engineers to apply the similar mechanism to bushing design. A typical conventional bushing is comprised of a rubber section enclosed by an inner and an outer metal, while a bushing filled with internal fluid is called a hydrobushing. Based on the fact that the fluid inside the hydrobushing generates the majority of the damping, the mathematical model of the hydrobushing used in this paper neglects the rubber damping effect to the system. The equations of fluid motion and conservation and system equilibrium equation determine its resonant frequency. The conclusion is that the resonant frequency is proportional to the ratio of the cross sectional area of the inertia track to the equivalent piston area and the square root of volumetric stiffness; and it is inversely proportional to the square root of the mass of the fluid in the inertia track. The predicted resonant frequency correlates well with the tested results.
Sharing availability information with InterruptMe (2011)

Workplace collaboration often requires interruptions, which can happen at inopportune times. Sharing availability information can reduce many of these untimely interruptions. However, designing a successful availability-sharing system requires finding the right balance to maximize the benefits and reduce costs for both the interrupter and interruptee. The main challenges for finding such balance lie in the acquisition of availability information from the interruptee and its delivery to the interrupter. In this demonstration, we show how common technical approaches in ubicomp can address some of the problems typically encountered in availability sharing. We present InterruptMe, a novel availability sharing system that uses sensor information to calculate multiple availability measures for each interruptee and that delivers this information in the periphery of the interrupter's attention by using a projected peripheral display and monitoring implicit inputs to the system.
Glycosylation Steps during Spiramycin Biosynthesis in Streptomyces ambofaciens : Involvement of Three Glycosyltransferases and Their Interplay with Two Auxiliary Proteins (2010)

Streptomyces ambofaciens synthesizes spiramycin, a 16-membered macrolide antibiotic used in human medicine. The spiramycin molecule consists of a polyketide lactone ring (platenolide) synthesized by a type I polyketide synthase, to which three deoxyhexoses (mycaminose, forosamine, and mycarose) are attached successively in this order. These sugars are essential to the antibacterial activity of spiramycin. We previously identified four genes in the spiramycin biosynthetic gene cluster predicted to encode glycosyltransferases. We individually deleted each of these four genes and showed that three of them were required for spiramycin biosynthesis. The role of each of the three glycosyltransferases in spiramycin biosynthesis was determined by identifying the biosynthetic intermediates accumulated by the corresponding mutant strains. This led to the identification of the glycosyltransferase responsible for the attachment of each of the three sugars. Moreover, two genes encoding putative glycosyltransferase auxiliary proteins were also identified in the spiramycin biosynthetic gene cluster. When these two genes were deleted, one of them was found to be dispensable for spiramycin biosynthesis. However, analysis of the biosynthetic intermediates accumulated by mutant strains devoid of each of the auxiliary proteins (or of both of them), together with complementation experiments, revealed the interplay of glycosyltransferases with the auxiliary proteins. One of the auxiliary proteins interacted efficiently with the two glycosyltransferases transferring mycaminose and forosamine while the other auxiliary protein interacted only with the mycaminosyltransferase.
Cocrystal Solubility Advantage Diagrams as a Means to Control Dissolution, Supersaturation, and Precipitation (2019)

Cocrystals are often more soluble than needed and pose unnecessary risks for precipitation of less soluble forms of the drug during processing and dissolution. Such conversions lead to erratic cocrystal behavior and nullify the cocrystal solubility advantage over parent drug (SA = <i>S</i><sub>cocrystal</sub>/<i>S</i><sub>drug</sub>). This work demonstrates a quantitative method for additive selection to control cocrystal disproportionation based on cocrystal solubility advantage (SA) diagrams. The tunability of cocrystal SA is dependent on the selective drug-solubilizing power of surfactants (SP<sub>drug</sub> = (<i>S</i><sub>T</sub>/<i>S</i><sub>aq</sub>)<sub>drug</sub>). This cocrystal property is used to generate SA-SP diagrams that facilitate surfactant selection and provide a framework for evaluating how SA influences drug concentration-time profiles associated with cocrystal dissolution, drug supersaturation, and precipitation (DSP). Experimental results with indomethacin-saccharin cocrystal and surfactants (sodium lauryl sulfate, Brij, and Myrj) demonstrate the log-linear relationship characteristic of SA-SP diagrams and the dependence of σ<sub>max</sub> and dissolution area under the curve (AUC) on SA with characteristic maxima at a threshold supersaturation where drug nucleation occurs. This approach is expected to streamline cocrystal formulation as it facilitates additive selection by considering the interplay between thermodynamic (SA) and kinetic (DSP) processes.
Data on the effect of NbC inoculants on the elastic and microstructural evolution of LBP-DED IN718 (2023)

The use of inoculants added to precursor powder is a method of influencing grain growth during fabrication. Niobium carbide (NbC) particles have been added to IN718 gas atomised powder for additive manufacturing via laser-blown-powder directed-energy-deposition (LBP-DED). The collected data in this study reveals the effects of the NbC particles on the grain structure, texture and elastic properties, and oxidative properties of LBP-DED IN718 in the As-DED and heat-treated conditions. The microstructure was investigated using X-ray diffraction (XRD), scanning electron microscopy (SEM) coupled with electron backscattered diffraction (EBSD), and transmission electron microscopy (TEM) coupled with energy dispersive X-ray spectroscopy (EDS). Resonant ultrasound spectroscopy (RUS) was used to measure the elastic properties and phase transitions during standard heat treatments. Thermogravimetric analysis (TGA) is used to probe the oxidative properties at 650°C.
Further Development and New Concepts for Bionic Sonar. Volume 2. Spectrogram Correlation. (1978)

This report documents theoretical studies of models of echolocation signal processing of dolphins and the testing of the effectiveness of these models for detecting and classifying small objects in introduced noise and reverberation. In this volume it is demonstrated that spectrogram correlation is a locally optimum detection operation for low SNR signals that have been passed through a random, time-varying process in Gaussian noise. For non-Gaussian noise local optimality is preserved by correlating stored data with a modified spectrogram. Detection and estimation performance of the spectrogram process is predicted and compared with psychophysical data. (Author)
Continuous tape coating by thermal evaporation (2003)

Among the various coating techniques, thermal evaporation currently allows the highest YBCO volume deposition rates because of its large area capability. This "simultaneous large area deposition" capability translates into long tape lengths when the deposition area is densely filled up with metal tape. On short rolling-assisted biaxially textured substrate samples thermal evaporation has already established critical current densities in excess of 1 MA/cm/sup 2/ at 77 K, with very promising performance in magnetic fields. Recently, the deposition technique has been scaled up using a multiturn tape winder giving a simultaneously coatable length of about 4 m of 1-cm-wide tape. The reel-to-reel tape deposition system is designed for long term continuous operation based on in-situ refillable evaporation sources and controlled using feedback from atomic absorption spectroscopy measurements in the vapor phase. Here, the authors present results on the first coated conductor tape continuously fabricated by this technique.
Science and technology of photography (1993)

The Photographic Sensors Spectral Sensitization Theory of Development Photographic Properties and Their Control Manufacture of Photographic Materials Emulsions Emulsion Supports Processing of Exposed Black-and-White Materials Color Photography Additive and Subtractive Color Processes Processing of Color Photographic Materials Dye Diffusion Processes Making of Color Prints Photographic Properties and Their Measurement Sensitometry and Densitometry Color Reproduction Photographic Materials and Applications Films Photographic Papers Environmental Aspects of Photographic Processing.
Сучасні погляди на генетичну детермінованість СТГ-секретуючих аденом гіпофіза (огляд літератури та власні дослідження) (2021)

Актуальність. В роботі наведений огляд сучасних даних літератури щодо генетичної складової в етіології та патогенезі гормонально активної аденоми гіпофіза, що секретує соматотропний гормон (СТГ) і клінічними проявами якої є синдром акромегалії та/або гігантизму— синдром множинної ендокринної неоплазії 1, синдром Мак-К’юна— Олбрайта, комплекс Карні, акрогігантизм (Х-зчеплений), сімейні ізольовані аденоми гіпофіза (FIPA). Матеріали та методи. Для виявлення мутацій в гені AIP та з метою верифікації FIPA були обстежені 26 хворих української популяції (19 жінок та 7 чоловіків), в яких акромегалія була діагностована в підлітковому або молодому віці, і проведений генетичний аналіз. Для визначення генетичної детермінованості щодо розвитку СТГ-секретуючої аденоми гіпофіза та диференціальної діагностики синдромів FIPA та MEN1 методом секвенування (MLPA— Ligation-dependent Probe Amplification) було проведене дослідження генів (MLPA, P244-C1) за участю екзонів 1–6 MEN1, (MLPA, P017-D1) AIP. Результати. Серед обстежених тільки у двох осіб були визначені мутації гена AIP. В одного хворого генетичний скринінг на мутацію гена MEN1 був негативним, і жодних клінічних симптомів, що свідчать про синдром Мак-К’юна— Олбрайта, не було виявлено. Варіант гетерозиготного місенсу c.714C&gt;G (p.Cys238Trp) виявлений у гені AIP. Цей аналіз гена AIP сумісний з генетичною схильністю до аденом гіпофіза. У нащадків даного пацієнта 50% шансів успадкувати цей варіант. У іншої хворої з діагнозом «синдром множинної ендокринної неоплазії типу1 (синдром Вермера): інсулінома, аденоми прищитоподібних залоз (2), первинний гіперпаратиреоз» встановлений варіант гетерозиготного місенсу c.134A&gt;G (p.Glu45Gly), що був виявлений у гені MEN1. Варіант c.l34A&gt;G (p.Glu45Gly), клас 4, ймовірно, є патогенним. Поширеність цього варіанта в загальній популяції невідома, тому він є дуже рідкісним. Висновки. Проведення генетичного аналізу є доцільним у хворих дитячого та молодого віку або в осіб, у яких СТГ-секретуюча макро-/гігантська аденома гіпофіза була діагностована в молодому віці (до 35 років), незалежно від сімейної обтяженості щодо аденом гіпофіза. У хворих з обтяженою спадковістю генетичний аналіз доцільно проводити у будь-якому разі для виявлення FIPA та прогнозування подальшого перебігу захворювання та ефективності лікування аналогами соматостатину.
GOSMOS: A Gate Oxide Short Defect Embedded in a MOS Compact Model (2003)

International audience
Das Tagesgeschäft des Vertriebsmitarbeiters (2012)

Die tägliche Verkaufspraxis hat es in sich. Wir spannen einen Bogen und gehen auf die wichtigen Aspekte wie z. B. das Zeitmanagement, die Klippen des Tagesgeschäftes, die Erfolgsstrategien, die Verkaufsförderung sowie der Entlohnungsprozess im Vertrieb ein. Anschließend setzen wir uns detailliert mit der Ausgestaltung der „ersten Wochen im Vertrieb“ auseinander. Dann folgt die Königsdisziplin im Vertrieb, das Key Account Management.
Middle atmosphere monitoring and dynamical coupling mechanisms: Ground-based lidar and satellite instruments synergy (2009)

International audience
A New Rapid and Non-radioactive Assay for Monitoring and Determining the Proliferation of Retinal Pigment Epithelial Cells (2003)

AlamarBlue is used to induce color and fluorescence in the microenvironment of activated cells. The alamarBlue assay was studied to determine if it could be used as a method of evaluating the number of retinal pigment epithelial (RPE) cells. A series of two-fold dilutions of RPE cells were placed into 96-well culture plates. The alamarBlue was added to the culture media after attaching the cells. The absorbance and fluorescence were measured consecutively at various intervals over a period of 24 hr. Cell viability were evaluated by means of the trypan blue exclusion method and flow cytometry using a combination of propidium iodide and annexin V was done to prove the safety of alamarBlue assay to the cells. Both the absorbance and the fluorescence had a linear relationship with the number of RPE cells. Exposing the RPE cells to alamarBlue was not detrimental to the cells. In conclusion, the alamarBlue assay constitutes a one-step, extremely simple, reproducible, economical and non-toxic procedure for evaluating the number of viable RPE cells.
Design and implementation of an autostereoscopic camera system (2021)

An autostereoscopic display provides the viewer with a three-dimensional image without the need for special glasses, and allows the user to look around objects in the image by moving the head left-right. The time-multiplexed autostereo display developed at the University of Cambridge has been in operation since late 1991. An autostereoscopic camera system has been designed and implemented. It is capable of taking video input from up to sixteen cameras, and multiplexing these into a video output stream with a pixel rate an order of magnitude faster than the individual input streams. Testing of the system with eight cameras and a Cambridge Autostereo Display has produced excellent live autostereoscopic video. This report describes the design of this camera system which has been successfully implemented and demonstrated. Problems which arose during this process are discussed, and a comparison with similar systems made.
Geophysical parametrization and interpolation of irregular data using natural neighbours (1995)

Summary An approach is presented for interpolating a property of the Earth (for example temperature or seismic velocity) specified at a series of ‘reference’ points with arbitrary distribution in two or three dimensions. The method makes use of some powerful algorithms from the field of computational geometry to efficiently partition the medium into ‘Delaunay’ triangles (in 2-D) or tetrahedra (in 3-D) constructed around the irregularly spaced reference points. The field can then be smoothly interpolated anywhere in the medium using a method known as natural-neighbour interpolation. This method has the following useful properties: (1) the original function values are recovered exactly at the reference points; (2) the interpolation is entirely local (every point is only influenced by its natural-neighbour nodes); and (3) the derivatives of the interpolated function are continuous everywhere except at the reference points. In addition, the ability to handle highly irregular distributions of nodes means that large variations in the scale-lengths of the interpolated function can be represented easily. These properties make the procedure ideally suited for ‘gridding’ of irregularly spaced geophysical data, or as the basis of parametrization in inverse problems such as seismic tomography. We have extended the theory to produce expressions for the derivatives of the interpolated function. These may be calculated efficiently by modifying an existing algorithm which calculates the interpolated function using only local information. Full details of the theory and numerical algorithms are given. The new theory for function and derivative interpolation has applications to a range of geophysical interpolation and parametrization problems. In addition, it shows much promise when used as the basis of a finite-element procedure for numerical solution of partial differential equations.
Restraining devices to counter the migration of HV cables in duct (2002)

This paper deals with the development, testing and installation of special devices on Hydro-Quebec's underground high-voltage transmission system which limit the displacement of cables installed in individual ducts. The devices are installed in manholes at the exit and/or entrance to the cable duct. The principle of two inverted cones is used to create a progressive restraining force applied to an axially-shifting cable. Several laboratory cycling tests were used to validate the performance of such a solution before its use on a 120 kV line.
Antioxidant and renoprotective activity of 2-hydroxypropyl-β-cyclodextrin in nephrectomized rats (2015)

These results suggest that the ingestion of HP-β-CD might result in a significant reduction in the levels of pro-oxidants in the gastrointestinal tract, such as uremic toxins, thereby inhibiting the subsequent development of oxidative stress in the systemic circulation.
Generative Adversarial Network-Based Method for Transforming Single RGB Image Into 3D Point Cloud (2018)

Three-dimensional (3D) point clouds are important for many applications, including object tracking and 3D scene reconstruction. Point clouds are usually obtained from laser scanners, but their high cost impedes the widespread adoption of this technology. We propose a method to generate the 3D point cloud corresponding to a single red–green–blue (RGB) image. The method retrieves high-quality 3D data from two-dimensional (2D) images captured by conventional cameras, which are generally less expensive. The proposed method comprises two stages. First, a generative adversarial network generates a depth image estimation from a single RGB image. Then, the 3D point cloud is calculated from the depth image. The estimation relies on the parameters of the depth camera employed to generate the training data. The experimental results verify that the proposed method provides high-quality 3D point clouds from single 2D images. Moreover, the method does not require a PC with outstanding computational resources, further reducing implementation costs, as only a moderate-capacity graphics processing unit can efficiently handle the calculations.
Supplementary Figure 3 from Loss of ARID1A Promotes Epithelial–Mesenchymal Transition and Sensitizes Pancreatic Tumors to Proteotoxic Stress (2023)

&lt;p&gt;Supplementary Figure 3. NVP-AUY922 toxicity in vivo and effect of gemcitabine treatment in ARID1A knock-out PDAC models in vitro and in vivo.&lt;/p&gt;
Exploiting Read/Write Asymmetry to Achieve Opportunistic SRAM Voltage Switching in Dual-Supply Near-Threshold Processors (2018)

Energy-efficient microprocessors are essential for a wide range of applications. While near-threshold computing is a promising technique to improve energy efficiency, optimal supply demands from logic core and on-chip memory are conflicting. In this paper, we perform static reliability analysis of 6T SRAM and discover the variance among different sizing configuration and asymmetric minimum voltage requirements between read and write operations. We leverage this asymmetric property in near-threshold processors equipped with voltage boosting capability by proposing an opportunistic dual-supply switching scheme with a write aggregation buffer. Our results show that proposed technique improves energy efficiency by more than 21.45% with approximate 10.19% performance speed-up.
Assessment of Reacting and Non-Reacting Supersonic Mixing (2007)

A computational study of sonic jet injection into a supersonic crossflow with and without combustion was performed. The gaseous injector was 3.226 mm in diameter and was injected 30 degrees to the horizontal. Simulated conditions involved sonic injection of hydrogen into a Mach 4 air cross-stream with a jet to freestream momentum flux ratio of 2.1. The numerical flow solver used was GASP v. 4.2. The inviscid fluxes were computed in three dimensions using third-order Roe Flux in the streamwise and lateral directions and third-order Van Leer flux in the vertical direction. The algorithms were chosen because of their robustness, shock resolution capabilities and efficiency. The Mentor Supersonic Transport (SST) turbulence model was used since the algorithm has good capability of solving both wall-bounded and free-shear flows. The reaction model used for hydrogen and air was a 9 species, 18 reactions model created by Drummond. The main results of this work can be summarized as: 1) modeling of combustion does not significantly alter the mixing behavior of the solution, 2) the size of the fuel plume is larger for the analysis which includes reacting flow, 3) the difference in size and shape of the plume between the reacting and non-reacting cases increases with downstream distance from injection.
A methodology for incorporating metallization loss in the electromagnetic modeling of the power distribution network (2008)

A methodology is presented for modeling the frequency dependence of the ohmic loss in the metallization planes of power distribution networks. The methodology relies on the definition of an effective, frequency-dependent, complex magnetic permeability. Numerical results are presented for the validation of the proposed methodology in the context of the extended segmentation procedure.
How yarn orientation limits fibrotic tissue ingrowth in a woven polyester heart valve scaffold: a case report (2020)

Transcatheter Aortic Valve Implantation (TAVI) has become today a popular alternative technique to surgical valve replacement for critical patients. However, with only six years follow up on average, little is known about the long-term durability of transcatheter implanted biological tissue. Moreover, the high cost of tissue harvesting and chemical treatment procedures favor the development of alternative synthetic valve leaflet materials. In that context, thin, strong and flexible woven fibrous constructions could be considered as interesting candidates. However, the interaction of textile material with living tissue should be comparable to biological tissue, and the Foreign Body Reaction (FBR) in particular should be controlled. Actually, the porosity of textile materials tends to induce exaggerated tissue ingrowth which may prevent the implants from remaining flexible. The purpose of this preliminary animal case study is to investigate the influence of the valve leaflet yarn orientation on the fibrotic tissue ingrowth. For that purpose the <i>in vivo</i> performances of 45° inclined yarn woven valve leaflets implanted in juvenile sheep model were assessed after three months implantation. Results bring out that in the frame of this case study the development of fibrosis is limited with a woven fabric valve obtained from 45° inclined yarns.