gebhart/patrepeval huggingface dataset:
Ein paraspastisches und sensibel-ataktisches Syndrom mit Eisenmangelanämie durch Hypocuprämie und/oder Hyperzinkämie? Ein Fallbericht (2004)

Ein 40jähriger Patient stellte sich mit seit sieben Monaten langsam progredienten paraspastischem Syndrom und sensibler Ataxie vor. An Vorerkrankungen bestand eine Eisenmangelanämie und eine Splenomegalie. Außer einer bekannten Anämie der Mutter waren Familien-, Sozial-, Medikamenten- und vegetative Anamnese unauffällig. Im Laufe der folgenden fünf Monaten zeigte sich eine Zunahme der Symptomatik mit deutlicher Abnahme der Gehfähigkeit, Inkontinenz und beginnender Dysphagie. Die bildgebende Diagnostik des Gehirns, Myelons, Thorax und Abdomens war nicht wegweisend. In der neurophysiologischen Untersuchung konnte eine Verzögerung der somatosensiblen und zentralmotorischen Leitunsgzeiten zu den Beinen nachgewiesen werden. Die Liquor-Diagnostik war bis auf erhöhte Lactatwerte um 3mM unauffällig (n<1,2). Im Blutbild fand sich eine hypochrome mikrozytäre Anämie bei Serum-Eisen (Fe) mit 14µg/dl (n 45–182) und eine Leukopenie. Im Normbereich waren die Werte für Thrombozyten, Elektrolyte, Leber-, Nieren- und Entzündungsparameter, Vitamine sowie Homocystein. Die paraneoplastischen Antikörper waren nicht erhöht. Eine Friedreich-Ataxie konnte genetisch ausgeschlossen werden. Auffällig waren erniedrigte Serum-Werte für Coeruloplasmin (Cp) mit 0,02g/l (n 0,22–0,40) und Kupfer (Cu) mit 14µg/dl (n 65–165) bei normalem 24h-Urin-Cu (<60µg). Die Zink-Spiegel (Zn) in Serum und 24h-Urin waren mit 29,5µmol/l (n 9,2–18,4) und 94µmol (n 2,8–13) erhöht. Die Magnesium-Spiegel in Serum und 24h-Urin waren 0,77mmol/l (n 0,77–1,03) und 5,9mmol/l (n 0,6–10). Eine Leberbiopsie erbrachte einen normalen Cu-Gehalt mit 12,6mg/kg (n 8–20) und erniedrigten Fe-Gehalt mit 107mg/kg (n 300–600) sowie histopathologisch normalen Befund. Basierend auf der Hypothese, dass es sich bei der neurologischen Symptomatik des Patienten um eine Folge des gestörten Cu/Zn-Haushaltes handelt (Hedera et al., 2003; Prodan et al., 2002), begannen wir mit einer täglichen oralen (4mg) und monatlichen intravenösen (5×2mg) Cu-Substitutionstherapie. Hierunter kam es zu einer Stabilisierung der klinischen Beschwerden des Patienten und einer Normalisierung der Werte für Cp (0,25g/l) und Cu (108µg/dl) im Serum des Patienten innerhalb weniger Wochen. Gegenwärtig interpretieren wir die hämatologischen und neurologischen Symptome als Folge des Kupfermangels. Ob die Hyperzinkämie eine Folge, Ursache oder ein Nebenphänomen des Kupfermangels ist, kann gegenwärtig nicht beantwortet werden und benötigt weitere Untersuchungen.
Effect of milk on patients with duodenal ulcers. (1986)

well controlled with topical agents until four days earlier, when he had purchased a 1 kg packet of Dead Sea Mineral Salts, which he added to his bathwater. Within two days he had become generally unwell and his psoriasis erythrodermic. He required admission to hospital and treatment with methotrexate and ord retinoids. His psoriasis remained well controlled until two years later, when it was noted to be once again inflamed and unstable; on direct questioning he admitted that he had recently again tried the Dead Sea Mineral Salts, though on this occasion he had used only about 250 g per bath. The stated ingredients of the preparation used (Dead Sea Health Products, Kibbutz Ein Gedi MP, Dead Sea, Israel) included potassium chloride 22-28%. magnesium chloride 30-34%, bromides 0-2-0-4%, and sulphates 0-1-0-2%.
Deliverable 4.1 – Threshold of nutritional quality for the Mediterranean production (2020)

Fish meal is being increasingly substituted in diets for gilthead sea bream and Sea bream with ingredients of terrestrial origin. The replacement of Fish Meal (FM) and Fish Oil (FO), as main protein and lipid sources by alternative ingredients, may alter the micronutrient contents in the diets, leading to deficiencies or excess in several micronutrients related to fish growth, feed efficiency and health (Fountoulaki et al., 2016; Dominguez et al., 2019a, 2019b). Nowadays, aquafeeds for Mediterranean species are mostly based on nutritional requirements determined for other species (NRC, 2011) and in many most micronutrients, the requirements have not been yet determined for fish species. Hence, those feeds may be deficient or overdosed in some nutrients and, consequently, negatively affect KPIs (Dominguez et al., 2016). PerformFISH WP4 aimed to define the recommended levels for minerals and vitamins in gilthead sea bass and Sea bream diets to produce Species-­‐Specific Nutrient Balanced Formulations and improve KPIs in relation to growth, feed utilization and mortality in Mediterranean aquaculture. Despite there is scarce information published about nutrients requirements and availability for gilthead sea bream and sea bass (essential fatty acids, protein,…), certain national and EU funded projects produced some information about the recommended dietary levels for specific nutrients (phospholipids, Zn, Vit B5…). This critical nutritional information has been compiled and collected by PerformFISH and included in Milestone 4.1. Besides, since the nutritional requirements of some nutrients essential to improve KPIs have not been yet determined for gilthead sea bream and sea bass, PerformFISH has conducted a series of studies to determine the recommended dietary levels to produce Species-Specific Nutrient Balanced Formulations. In the case of gilthead sea bream, the trials were conducted to define the effect of fat-­‐soluble vitamins (A, K, and D), minerals (Cu, Mn and Se) and B group vitamins (B1, B9, and B12), whereas for Sea bass different profiles of chelated minerals have been tested. Deliverable 4.1 is mainly composed of the major experimental findings and, thus, the nutrient recommendations to define the threshold of nutritional quality for both fish species as keystone elements of the Mediterranean production.
High magnesium mobility in ternary spinel chalcogenides (2017)

Magnesium batteries appear a viable alternative to overcome the safety and energy density limitations faced by current lithium-ion technology. The development of a competitive magnesium battery is plagued by the existing notion of poor magnesium mobility in solids. Here we demonstrate by using ab initio calculations, nuclear magnetic resonance, and impedance spectroscopy measurements that substantial magnesium ion mobility can indeed be achieved in close-packed frameworks (~ 0.01-0.1 mS cm<sup>-1</sup> at 298 K), specifically in the magnesium scandium selenide spinel. Our theoretical predictions also indicate that high magnesium ion mobility is possible in other chalcogenide spinels, opening the door for the realization of other magnesium solid ionic conductors and the eventual development of an all-solid-state magnesium battery.
Cloning and characterization of Î²-galactoside and Î²-glucoside hydrolysing enzymes of Thermotoga maritima (1993)

A gene library of the hyperthermophilic bacterium Thermotoga maritima strain MSB8 was constructed in Escherichia coli. Two non-related T. maritima chromosomal DNA fragments were physically characterized. They conferred the synthesis of thermostable X-Gal (5-bromo-4-chloro-3-indolyl-β-d-galactopyranoside)-hydrolysing activity upon the host organism. The biochemical properties of the recombinant enzymes indicated that genes for a β-galactosidase (BgaA) and a broad-specificity β-glucosidase (Bg1A) had been isolated. The genes were designated bgaA and bglA, respectively. According to analytical size exclusion chromatography data, BgaA and BglA had native molecular masses of approximately 240 kDa and 95 kDa, respectively. Both enzymes apparently have dimeric subunit structure. An additional β-glucosidase (designated BglB) activity, clearly distinct from BglA in terms of substrate specificity, could be detected in a crude extract of T. maritima.
The Role of the Endoscopic Endonasal Approach in the Treatment of Trigeminal Schwannomas (2017)

Background: Trigeminal schwannomas may require a variety of approaches depending upon their growth pattern. The Endoscopic Endonasal Approach (EEA) provides the additional option of a ventral surgical corridor for the treatment of these tumors.
Spectrum separation resolves partial‐volume effect of MRSI as demonstrated on brain tumor scans (2008)

Magnetic resonance spectroscopic imaging (MRSI) is currently used clinically in conjunction with anatomical MRI to assess the presence and extent of brain tumors and to evaluate treatment response. Unfortunately, the clinical utility of MRSI is limited by significant variability of in vivo spectra. Spectral profiles show increased variability because of partial coverage of large voxel volumes, infiltration of normal brain tissue by tumors, innate tumor heterogeneity, and measurement noise. We address these problems directly by quantifying the abundance (i.e. volume fraction) within a voxel for each tissue type instead of the conventional estimation of metabolite concentrations from spectral resonance peaks. This 'spectrum separation' method uses the non-negative matrix factorization algorithm, which simultaneously decomposes the observed spectra of multiple voxels into abundance distributions and constituent spectra. The accuracy of the estimated abundances is validated on phantom data. The presented results on 20 clinical cases of brain tumor show reduced cross-subject variability. This is reflected in improved discrimination between high-grade and low-grade gliomas, which demonstrates the physiological relevance of the extracted spectra. These results show that the proposed spectral analysis method can improve the effectiveness of MRSI as a diagnostic tool.
Audit of laparoscopic surgery for tubal pregnancy in a district general hospital (2002)

ABSTRACT Objective To measure the proportion of tubal pregnancies managed laparoscopically and those suitable for laparoscopic surgery based on departmental guidelines in a district general hospital in the northwest of England. Design A retrospective audit of the surgical management of tubal pregnancies over a 12‐month period. Setting A district general hospital. Participants All women operated on for tubal pregnancy in Sharoe Green Hospital between 1 January 2001 and 31 December 2001. Methods Cases of tubal pregnancy requiring surgery during 2001 were identified from the computerized theatre log. The case notes of these women were reviewed and assessed as to whether they were managed appropriately by laparotomy and laparoscopic surgery. Audit standard All cases (100%) to be managed appropriately with laparoscopic surgery in accordance with Royal College of Obstetricians and Gynaecologists (RCOG) guidelines. Results Fifty‐two possible cases were identified. Five were not tubal pregnancies upon review of the notes and therefore excluded. Nine case notes could not be traced by the audit department. The remaining 38 cases of tubal pregnancy were reviewed. A total of 18% of cases underwent appropriate laparotomy and 82% were deemed suitable for operative laparoscopy. Only 39% of tubal pregnancies deemed suitable were managed by appropriately by laparoscopic surgery. Conclusion The majority of cases of tubal pregnancy were not managed appropriately with laparoscopic surgery in Sharoe Green Hospital. The proportion of tubal pregnancies suitable for laparoscopic surgery in a district general hospital is approximately 82%.
Direct Titanium‐Mediated Conversion of Ketones into Enamides with Ammonia and Acetic Anhydride (2012)

Eine einstufige Umsetzung von Ketonen zu N-Acetylenamiden wurde entwickelt. Der Prozess nutzte sichere und billige Reagentien, verläuft unter milden Bedingungen und toleriert diverse funktionelle Gruppen. Der Zusatz von edte (N,N,N′,N′-Tetrakis(2-hydroxyethyl)ethylendiamin) bringt das Ti-Alkoxid in Lösung und ermöglicht eine einfache extraktive Aufarbeitung. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Estimation and presentation of blood flow and velocity from angiographic scans in the human cerebral arterial system (2008)

This paper provides an overview of blood flow in the arterial system and aims to estimate the blood velocity from cerebral angiography scans without having acquired data on velocity by using Murray's Law. The estimation technique post-processes the scan and provides crucial 3D visual data for the development of a visualization program of the blood flow in the human brain.
The Role of an Engineering Oriented Medical Research Group in Developing Improved Methods and Devices for Achieving Ventricular Defibrillation: The University of Missouri Experience (1993)

Physical scientists and engineers have played important roles in helping to expand our understanding of the factors that influence the defibrillation process and in developing improved methods and devices for achieving cardiac ventricular defibrillation. The long-term experience of one engineering oriented group, based in a clinical department of a medical school, is summarized. Emphasized are the features of a series of research defibrillators that facilitated the generation of an extensive experimental database from studies in dogs and calves, the development of the first automatic implantable defibrillator to be successfully used in dogs, and studies that furnished the rationale for the widespread use of the uniphasic truncated exponential waveform and for the increasing interest in a variety of biphasic and multiphasic waveforms. Also considered are studies concerning the scaling of the defibrillatory shock with subject size and the role of compound units, defibrillation threshold, and contour graphs in the presentation and interpretation of data.
Engineering Test Report Paint Waste Reduction Fluidized Bed Process Demonstration at Letterkenny Army Depot Chambersburg, Pennsylvania (1991)

Degreasing and removal of paint from metal parts are processes performed at several Army depots across the country as part of vehicle and equipment rebuilding operations. These processes generate many tons of hazardous waste and release some hazardous materials into the workplace because most of them incorporate toxic chlorinated solvents or caustic soda These substances also produce sludges that are classified as hazardous waste. U.S. Army Depot Support Command (DESCOM), as part of its hazardous waste minimization program, has established as a goal the elimination of hazardous waste generation from paint stripping operations. Through specific research and development projects, the U.S. Army's Toxic and Hazardous Materials Agency (USATHAMA) assists Army Depots in developing and evaluating methods for minimizing the quantities of hazardous wastes that they generate. Chemical Cleaning, Paint Stripping, Hazardous.
Sodium Ion Mobility in NaxCoO2 (0.6 < x < 0.75) Cobaltites Studied by 23Na MAS NMR (2009)

Various P2 and P'3-Na(x)CoO(2) phases, with x ranging approximately from 0.6 to 0.75, have been studied by variable-temperature (23)Na magic angle spinning (MAS) NMR. Signal modification versus temperature plots clearly show that Na(+) ions are not totally mobile at room temperature on the NMR time scale. As the temperature increases, the line shape change of the (23)Na MAS NMR signal differs for the P2 and P'3 stackings and is interpreted by the differences of Na(+) ion sites and of sodium diffusion pathways in the two structures.
Effects of Learning on Performance When Computerized Dynamic Posturography Assessments Are Repeated (2008)

Background: Computerized dynamic posturography is widely used to measure balance control performance. Clinically, performance is assessed by comparing individual data against standards obtained from a normative population. When performing repeated assessments to track performance changes, one must be concerned with the influence of learning effects. Subjects do not have the opportunity to practice before the first session, and often a second session is not performed prior to an experiment. Thus, the objective of this activity was to examine learning effects on balance control performance. We hypothesize that subjects will perform better on the second session when compared to the first, and that the difference will be greater for more difficult conditions. Methods: Data were collected from 204 subjects using the NeuroCom Equitest system during quiet stance with arms crossed at the chest on up to two sessions. All subjects performed standard sensory organization tests (SOTs) including 1) normal vision, fixed support; 2) absent vision, fixed support; 3) sway-referenced vision, fixed support; 4) normal vision, swayreferenced support; 5) absent vision, sway-referenced support; and 6) sway-referenced vision, sway-referenced support. 120 of these subjects performed modified sensory organization tests (mSOTs 2 and 5) which included static (20 back) and dynamic (20, 0.33Hz) head tilts. Median equilibrium scores (mEQ) were calculated from peak-to-peak anterior-posterior sway across trials. Data collected on the first session were then compared with the second to examine learning effect. Results: There were no differences in mEQ scores between the first and second sessions for SOTs 1, 2, and 4, while mEQ scores were higher for the second session when compared to the first for SOTs 3, 5, and 6 and for all mSOTs. Discussion: An additional familiarization session or practice trials prior to the first session may be necessary for more challenging SOT and mSOT conditions to minimize learning effect.
Design of Parallel-series Microstrip Patch Antenna Array at mmWave, for future 5G applications (2019)

In this work, a new patch antenna array containing 16-elements, Parallel-series Feed operated at millimeter waves, for 5G mobile wireless applications have been designed and realized. The proposed antenna contains 16-elements excited by one port, through a Y-Junction power divider. The array has a bandwidth of 27.5 to 28. 35GHz and a high gain of 17.5dBi.
4-Aroylbenzils and related compounds (1967)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT4-Aroylbenzils and related compoundsHilton Greenberg, Theodorus Van Es, and O. G. BackebergCite this: J. Org. Chem. 1967, 32, 10, 2964–2966Publication Date (Print):October 1, 1967Publication History Published online1 May 2002Published inissue 1 October 1967https://pubs.acs.org/doi/10.1021/jo01285a006https://doi.org/10.1021/jo01285a006research-articleACS PublicationsRequest reuse permissionsArticle Views93Altmetric-Citations4LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Apply multiple target for advanced gate ADI critical dimension measurement by scatterometry technology (2012)

Scatterometry-based metrology measurements for advanced gate after-develop inspection (ADI) and after-etch inspection (AEI) structures have been well proven<sup>1</sup>. This paper discusses the metrology challenges encountered in implementing a production-worthy methodology for accurately measuring gate ADI middle CD (MCD) and sidewall angle (SWA) to monitor focus and exposure dose. A Multi-Target Measurement (MTM) methodology on KLA-Tencor's SpectraShape 8810 was evaluated on its ability to characterize and measure FEM (Focus Exposure Matrix) and EM (Exposure Matrix) wafers. The correlation of MCD and SWA to the focus and exposure dose was explored. CD-SEM measurements were used as a reference to compare the accuracy of scatterometry MCD measurements. While there was no reference tool available to compare scatterometry SWA measurements, the SWA and focus tracking on the FEM wafer were verified. In addition to the MTM methodology evaluation, a fleet of four SpectraShape 8810 tools was evaluated to measure the fleet's capability for in-line monitoring in high volume manufacturing. The final results confirmed that the Multi-Target Measurement approach on SpectraShape 8810 is an effective solution for gate ADI metrology and the robust fleet matching performance would enable in-line monitoring use.
Poster 77: The Effect of Nitric Oxide on Compound Action Potential Thresholds in the Cochlea (1995)

The purpose of this study was to evaluate the effect nitric oxide (NO) has on hearing and to describe how these actions are mediated. In a gerbil model, cochlear action potential (CAP) thresholds were tested after cochlear perfusion of control and test solutions. Hearing thresholds were obtained before and after the drilling of perfusion holes and after each perfusion. The scala tympani was perfused from the first turn to the apex of the cochlea. There were four study groups in this experiment. The first control group was perfused with artificial perilymph (APS). The second group was perfused with 1 × 10-4 mol/L methylene blue (MB) and 2 × 10-5 mol/L sodium dodecyl sulfate (SDS) in APS. The third group was perfused with 1 × 10-3 mol/L sodium nitroprusside (SNP), an NO donor. The fourth group was perfused with 1 × 10-3 mol/L SNP in the MB/SDS/APS solution. The drilling of perfusion holes and the perfusion of APS, APS/SDS, and MB/SDS/APS solutions did not affect CAP thresholds. SNP caused a significant elevation of approximately 40 db SPL of the CAP threshold over APS baselines. SNP with MB resulted in significant CAP threshold elevations of approximately 10 dB SPL compared with baseline MB/APS perfusions, yet these elevations were significantly lower than those seen in SNP perfusions without MB. Our results suggest that NO does play a role in cochlear neuromodulation. These actions are mediated in part through NO's activation of guanylate cyclase and the second messenger system of cyclic guanosine monophosphate. Because inhibition of guanylate cyclase did not completely protect CAP thresholds from NO's effects, there must be other pathways of NO's actions in the cochlea other than those linked to cyclic guanosine monophosphate.
ChemInform Abstract: Low Temperature Precursor Route for Highly Efficient Spherically Shaped LED‐Phosphors M2Si5N8:Eu2+ (M: Eu, Sr, Ba). (2009)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.