gebhart/patrepeval huggingface dataset:
Constituents of the Essential Oils from Two Varieties of Cymbopogon distans (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTConstituents of the Essential Oils from Two Varieties of Cymbopogon distansA. B. Melkani, P. Joshi, A. K. Pant, C. S. Mathela, and Vasu DevCite this: J. Nat. Prod. 1985, 48, 6, 995–997Publication Date (Print):November 1, 1985Publication History Published online1 July 2004Published inissue 1 November 1985https://pubs.acs.org/doi/10.1021/np50042a025https://doi.org/10.1021/np50042a025research-articleACS PublicationsRequest reuse permissionsArticle Views158Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Two new xeniolides from a TaiwaneseXeniasoft coral (2007)

Chromatographic investigation of an extract of the octocoral Xenia umbellata afforded two new diterpenes, xenibelatols A (1) and B (2), in addition to three known xenicane diterpenes, 7,8-oxidoisoxeniolide (3), 9-hydroxyxeniolide F (4), and florlide C, and a cadinene sesquiterpene, xenitorin A (5). The structures were elucidated through spectroscopic analysis, especially 2D NMR.
A survey of distributed shared memory systems (2002)

Distributed shared memory (DSM) systems have attracted considerable research efforts recently, since they combine the advantages of two different computer classes: shared memory multiprocessors and distributed systems. The most important one is the use of shared memory programming paradigm on physically distributed memories. One possible classification taxonomy, which includes two basic criteria and a number of related characteristic, is proposed and described. According to the basic classification criteria-implementation level of DSM mechanism-systems are organized into three groups: hardware, software, and hybrid DSM implementations. The paper also presents an almost exhaustive survey of the existing solutions in an uniform manner, presenting their DSM mechanisms and issues of importance for various DSM systems and approaches.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Curing kinetics and thermal properties of diglycidylether of bisphenol A with various diamines (2001)

Abstract To prepare a high‐performance epoxy, we synthesized three types of diamines { N,N ′‐(4,4′‐diphenylether)‐bis(4‐aminophthalimide), 4,4′‐bis( p ‐aminophenoxy)dibenzalphentaerythriol, and 2,2′‐bis[4‐( p ‐aminobenzoyl)phenyl]propane} as epoxy curing agents with a two‐step reaction sequence. The structures of the synthesized diamines were confirmed with Fourier transform infrared and nuclear magnetic resonance spectroscopy. The curing kinetics and thermal stability of the cured epoxy resin with diglycidylether of bisphenol A were estimated with differential scanning calorimetry and thermogravimetric analysis under a nitrogen atmosphere. The kinetics parameters were determined with the Ozawa and Kissinger equations. © 2001 John Wiley &amp; Sons, Inc. J Appl Polym Sci 81: 279–284, 2001
Bioactive Enmein-Type ent-Kaurane Diterpenoids from Isodon phyllostachys (2016)

Thirty-two enmein-type ent-kaurane diterpenoids, including 13 new compounds, were isolated from the aerial parts of Isodon phyllostachys. Compounds 1 and 2 are the first examples of 3,20:6,20-diepoxyenmein-type ent-kauranoids, and the structures of these new compounds were established mainly by analyzing NMR and HREIMS data. The absolute configurations of 1 and 8 and the relative configuration of 9 were determined using single-crystal X-ray diffraction. Compounds 11, 15, 20, and 21 were active against five human cancer cell lines (HL-60, SMMC-7721, A-549, MCF-7, and SW-480), with IC50 values ranging from 1.2 to 5.0 μM. Compounds 3, 11, 15, 17, 20, 21, 25, and 29 strongly inhibited NO production in LPS-stimulated RAW264.7 cells, with IC50 values ranging from 0.74 to 4.93 μM.
Cadence selection affects metabolic responses during cycling and subsequent running time to fatigue (2005)

The increase in Tmax after FCC-20% may be associated with the lower metabolic load during the final minutes of cycling compared with the other sessions. However, the lack of significant differences in metabolic responses and stride pattern between the run sessions suggests that other mechanisms, such as changes in muscular activity, probably contribute to the effects of cadence variation on Tmax
Software zur automatischen Quantifizierung von Belüftungszuständen bei akutem Lungenversagen in dynamischen CT-Aufnahmen der Lunge1 (2001)

An automatic software tool is presented for lung segmentation in healthy lungs and in ARDS. Aerated lung and atelectasis were identified with high accuracy. This post-processing tool allows for a quantitative, CT based assessment of ventilation and recruitment processes in the lung. Thus, it may help to optimize ventilation patterns in patients with ARDS.
Personalization technologies (2005)

By leveraging customer reactions to personalized products and services, companies continuously improve their personalization processes through an iterative feedback loop resulting in the `virtuous cycle' of personalization.
Maternal lipids at mid‐pregnancy and the risk of preterm delivery (2012)

Extremely low TC, HDLc, and LDLc were associated with a modest increase in risk of medically indicated preterm delivery, whereas high TC, LDLc and TG modestly increased the risk of spontaneous preterm delivery. Further research is needed to uncover explanations for these associations and to identify optimal ranges for maternal lipids.
Characterization of gastrointestinal digests from animal and vegetal proteins and effects on CCK and GLP-1 secretion in STC-1 cells (2018)

Trabajo presentado a la Food Colloids Conference, celebrada en Leeds (UK) del 8 al 11 de abril de 2018.
MicroRNA-19a-PTEN Axis Is Involved in the Developmental Decline of Axon Regenerative Capacity in Retinal Ganglion Cells (2020)

Irreversible blindness from glaucoma and optic neuropathies is attributed to retinal ganglion cells (RGCs) losing the ability to regenerate axons. While several transcription factors and proteins have demonstrated enhancement of axon regeneration after optic nerve injury, mechanisms contributing to the age-related decline in axon regenerative capacity remain elusive. In this study, we show that microRNAs are differentially expressed during RGC development and identify microRNA-19a (miR-19a) as a heterochronic marker; developmental decline of miR-19a relieves suppression of phosphatase and tensin homolog (PTEN), a key regulator of axon regeneration, and serves as a temporal indicator of decreasing axon regenerative capacity. Intravitreal injection of miR-19a promotes axon regeneration after optic nerve crush in adult mice, and it increases axon extension in RGCs isolated from aged human donors. This study uncovers a previously unrecognized involvement of the miR-19a-PTEN axis in RGC axon regeneration, and it demonstrates therapeutic potential of microRNA-mediated restoration of axon regenerative capacity in optic neuropathies.
Determination of the Nicotine Content of Various Edible Nightshades (Solanaceae) and Their Products and Estimation of the Associated Dietary Nicotine Intake (1999)

This investigation was initiated as a result of proposals in the literature that dietary nicotine intake could contribute to the level of nicotine metabolites in biological fluids such as salivary cotinine concentration. Nicotine concentration was determined in several frequently consumed vegetables from the nightshade family (Solanaceae) (i.e., tomatoes, potatoes, aubergines, and peppers), as well as in some of their processed products. The edible Solanaceae fruit analyzed in this investigation were found to contain relatively consistent amounts of nicotine in the range of 2−7 μg/kg for fresh fruits. Nevertheless, the nicotine concentrations of the investigated tomato varieties decreased significantly with increasing degree of ripening of the fruits. In addition, a variety of black as well as green teas was investigated for the nicotine content. Nicotine content in tea leaves was found to be highly variable and sometimes much larger than in the Solanaceae fruits. On the basis of the observed concentrations and the respective food consumption data for different countries, a distributive analysis of the results suggests that the mean daily dietary nicotine intake for the population of the countries for which consumption data were available is approximately 1.4 μg/day, 2.25 μg/day at the 95th percentile. Keywords: Nicotine; Solanaceae; dietary nicotine intake; vegetables; tea
Theoretical analysis of a piezoelectric thin film resonator with acoustic quarter-wave multilayers (2002)

The purpose of this paper is to theoretically analyse the piezoelectric thin film resonator with acoustic multilayers by considering acoustic loss, electrode thickness, and thickness deviation of respective layers including the piezoelectric film. The dependence of the resonance and antiresonance frequencies, the Q-factor, and the effective electromechanical coupling factor on resonator parameters, especially on the total number of multilayers, is discussed in contrast to the case of a piezoelectric film with traction-free surfaces.
Long-term results of hybrid endovascular repair for thoraco-abdominal aortic aneurysms☆ (2010)

The hybrid TAAA-repair protocol yielded satisfactory results. Although thorough follow-up is required for visceral bypass, this procedure could become the standard for TAAAs.
Instruments de musique à vent : Acoustique et facture (2014)

National audience
Small-Molecule Inhibitor of the Oncogenic KRASG12C Mutant for the Treatment of Currently Incurable Cancer (2022)

ADVERTISEMENT RETURN TO ISSUEPREVPatent HighlightNEXTSmall-Molecule Inhibitor of the Oncogenic KRASG12C Mutant for the Treatment of Currently Incurable CancerRobert B. Kargbo*Robert B. KargboUsona Institute, 277 Granada Drive, San Luis Obispo, California 93401-7337, United States*[email protected]More by Robert B. Kargbohttps://orcid.org/0000-0002-5539-6343Cite this: ACS Med. Chem. Lett. 2022, 13, 5, 767–769Publication Date (Web):April 20, 2022Publication History Received2 April 2022Published online20 April 2022Published inissue 12 May 2022https://pubs.acs.org/doi/10.1021/acsmedchemlett.2c00152https://doi.org/10.1021/acsmedchemlett.2c00152editorialACS PublicationsCopyright © Published 2022 by American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views2361Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (789 KB) Get e-AlertscloseSUBJECTS:Cancer,Cell signaling,Genetics,Inhibitors Get e-Alerts
Isolation and Characterization of Normal Adult Human Epithelial Pluripotent Stem Cells (2003)

Both reproductive and therapeutic cloning of human stem cells have been made possible with recent technological advances in the isolation of embryonic stem cells and of pluripotent stem cells from adult tissues. We have isolated normal human kidney and human breast epithelial stem cells, as well as having characterized "immortalized" cells from human neuronal and human pancreatic tissue (Trosko et al., Methods 20:245-264, 2000). The isolation was motivated by the stem cell theory of carcinogenesis. Based on the assumption that stem cells would not express connexin genes, nor have functional gap junctional intercellular communication (GJIC), we have demonstrated that the human kidney, breast, neuronal, and pancreatic stem cells can divide either symmetrically or asymmetrically, depending on whether they are grown in microenvironmental conditions that suppress GJIC (the undifferentiated, proliferative state) or induce GJIC (the differentiated state). Normal breast epithelial stem cells appear to be intrinsically "immortal" until induced to express GJIC, at which time, with appropriate substrate and microenvironmental nutrients, they can form three-dimensional "organoids." expressing markers associated with the mature mammary tissue and forming a physical structure very similar to the in vivo budding, ductal structures. The breast stem cells can be prevented from "mortalizing" and can be converted to neoplastic cells, which maintain many phenotypes of the stem cells.
Thermal stability of ultra-thin Co recording media (1998)

Ultra-thin Co/Cr films were fabricated by RF diode sputtering. The highly exchange coupled Co grains were successfully isolated by post deposition processing. The microstructure was studied with TEM and a very small physical grain size was observed. The measurement of /spl Delta/M curves showed that the grain to grain interaction changed from positive to negative. Time dependent magnetic measurements showed significant thermal decay effects. It was also found that the use of CrMn underlayers instead of pure Cr further isolated the Co grains.
Supplementary Materials and Figure Legends from Therapy-Induced Senescence Enhances the Efficacy of HER2-Targeted Antibody–Drug Conjugates in Breast Cancer (2023)

&lt;p&gt;Extended Materials and Methods and Supplementary figures with legends&lt;/p&gt;
RF power measurement in D-band using down-converter calibrated by three-mixer method (2012)

To establish an RF power standard above 110GHz, we have developed a measurement system using a down-conversion mixer with a spectrum analyzer, and the conversion loss of the mixer was determined by the three-mixer method. This method measures the three transmission S-parameters (S21) of three mixer pairs using a vector network analyzer. The experimental results proved that the three-mixer method can determine the conversion loss of mixers with an uncertainty of 0.5dB (level of confidence: 95%) in the entire range of the D-band. Using this uncertainty and the uncertainty of the spectrum analyzer, the proposed system can measure the RF power in the D-band with an uncertainty of less than 2.0dB.
Electrostatic Fields near the Active Site of Human Aldose Reductase: 2. New Inhibitors and Complications Caused by Hydrogen Bonds (2011)

Vibrational Stark effect spectroscopy was used to measure electrostatic fields in the hydrophobic region of the active site of human aldose reductase (hALR2). A new nitrile-containing inhibitor was designed and synthesized, and the X-ray structure of its complex, along with cofactor NADP(+), with wild-type hALR2 was determined at 1.3 Å resolution. The nitrile is found to be in the proximity of T113, consistent with a hydrogen bond interaction. Two vibrational absorption peaks were observed at room temperature in the nitrile region when the inhibitor binds to wild-type hALR2, indicating that the nitrile probe experiences two different microenvironments, and these could be empirically separated into a hydrogen-bonded and non-hydrogen-bonded population by comparison with the T113A mutant, in which a hydrogen bond to the nitrile is not present. Classical molecular dynamics simulations based on the structure predict a double-peak distribution in protein electric fields projected along the nitrile probe. The interpretation of these two peaks as a hydrogen bond formation-dissociation process between the probe nitrile group and a nearby amino acid side chain is used to explain the observation of two IR bands, and the simulations were used to investigate the molecular details of this conformational change. Hydrogen bonding complicates the simplest analysis of vibrational frequency shifts as being due solely to electrostatic interactions through the vibrational Stark effect, and the consequences of this complication are discussed.
Induction of Parturition with Aglepristone in Various Sized Bitches of Different Breeds. (2009)

The objective of this study was to confirm in various breeds of dogs the efficacy and safety of a parturition induction treatment described to be successful in Beagle dogs. Parturition was induced in seven various sized pregnant bitches of different breeds, with 15 mg aglepristone per kg at day 59-61 post-estimated ovulation day, followed 24 h later by 0.15 IU oxytocin per kg subcutaneous injections every 2 h. Two bitches were small-sized bitches (<10 kg), three bitches were large-sized bitches (30-40 kg) and two bitches were giant bitches (>40 kg). The results were compared to a control group (n = 6), in which bitches underwent a natural delivery in the same environmental conditions as the induced group. In the induced group, parturition was successfully induced in 7/7 bitches. The first pup in a litter was born on average 25.9 +/- 3.29 h after aglepristone administration (21-30 h). Two of seven bitches from the small-sized group delivered some of their pups before the first administration of oxytocin. The mean duration of parturition was 9.6 +/- 5.4 h vs 8.0 +/- 4.8 h in the control group. The mean interval between two successive pups being delivered was 115.6 +/- 82.8 min (34-265) vs 68.8 +/- 24.5 min in the control group (p < 0.03). The mean weight at parturition did not differ significantly between the two groups. One litter of four Yorkshire Terrier pups in the induced group were premature at the time of birth and died between 19 and 29 h post-delivery. This study, although on a very limited number of dogs, confirms the efficacy of the aglepristone/oxytocin protocol to induce parturition in dogs.
Relationship between environmental noise, sound quality, soundscape (2012)

The term “Environmental Noise” is well known for many years. Its characteristic is often described by parameters like A-weighted SPL, Lden, Lday, Levening, Lnight. These parameters can be measured and calculated. In the field of “Sound Quality” psychoacoustic parameters are additionally used like loudness, sharpness, roughness and others, which can be measured but not calculated for a complex sound field. On an international level a standard is available only for the loudness of stationary sounds so far. The “relatively” young term “soundscape” will be standardized in ISO 12913-1. Moreover, as it considers human perception including cognitive aspects, context and interaction it goes beyond physics and psychoacoustics. It involves a concept, where environmental noise is not reduced to an averaged quantity evoking only unpleasantness feelings estimated by statistical probabilities, but understanding noise as a valuable resource, which can be purposefully utilized. In spite of recent progresses in the standardization process lots of misinterpretations occur in practical use, where the terms are heavily mixed up. Environmental noise and soundscape are no synonyms, for example low noise level does not directly mean a good sound quality. The paper will clarify options and limitation of both terms.
Measurements of intrinsic properties of high power CW single quantum well GaInNAsSb/GaAs lasers at 1.5 /spl mu/m (2004)

We present measurements of relative intensity noise (RIN) and non-radiative recombination of 1.5 /spl mu/m GaInNAsSb edge-emitting lasers. Differential gain of 4/spl times/10/sup -18/cm/sup 2/, K-factor of 0.75 ns and RIN below -150 dB/Hz at 7 mW were measured.
Broad-band multisection electrooptic modulators (1988)

A general solution has been derived for expressing the conversion of power from a base frequency to a modulation sideband using a multisection electrooptic modulator. The objective is to obtain broadband frequency modulation of a laser by the use of multiple collinear electrooptic crystals with microwave power levels well below the breakdown threshold. It is found that segmented structures lead to greater bandwidths, which increase with the number of modular sections. This is achieved by adjusting the phases of microwaves between sections to maximize the single-sideband conversion efficiency. It is shown that a 10.6- mu m CO/sub 2/ laser modulator with six geometrically identical CdTe sections can potentially achieve a 3-dB bandwidth of nearly 6 GHz using a 10-kW traveling-wave tube operating at 16-GHz center frequency.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Multitechnique Investigation of Extruded Clay Brick Microstructure (2011)

Despite the omnipresence of clay brick as construction material since thousands of years, fundamental knowledge about the link between composition, microstructure, and mechanical performance is still scarce. In this paper, we use a variety of advanced techniques of experimental mechanics and material characterization for extruded clay brick for masonry, that range from scanning electron microscopy (SEM) coupled with energy‐dispersive X‐ray spectroscopy, mercury intrusion porosimetry, to instrumented nanoindentation and macroscopic strength and durability tests. We find that extruded clay brick possesses a hierarchical microstructure: depending on the firing temperature, a “glassy” matrix phase, which manifests itself at submicrometer scales in form of neo‐crystals of mullite, spinel‐type phase, and other accessory minerals, forms either a granular or a continuum matrix phase that hosts at submillimeter scale the porosity. This porous composite forms the backbone for macroscopic material performance of extruded brick, including anisotropic strength, elasticity, and water absorption behavior.
An Axial Air-AP Reluctance Motor for Variable Speed Applications (1974)

The disc motor is a brushless, reluctance-principle; rotating machine that has been developed to the prototype stage for traction and variable speed drive application. It is attractive for these and other applications because of a simple magnetic structure which has potential for very low assembly costs, and because it can be controlled over a wide range of speed and torque by thyristor circuits of comparable simplicity to the chopper circuit used with do traction motors. The motor theory is briefly discussed and laboratory measurements of machine performance is presented.