gebhart/patrepeval huggingface dataset:
Looking to speak (2013)

This study investigates the different temporal orders that manifest in interactions involving a participant using an Augmentative Alternative Communications (AAC) device. Studies examining the use of AAC devices have regularly incorporated a particular understanding of temporality by using time as a measuring device to compare inter- and intra-individual action. In this paper we present an alternative perspective on time-in-interaction by showing how participants attend to time by examining their interactive behavior. Here, time is conceived in terms of how participants experience the duration and unfolding of a particular utterance. Through a close analysis of an interaction between a man with late-stage ALS and his wife, this paper shows how different orientations to time can underpin breakdowns of intersubjectivity. The analysis traces elements of this temporal disconnect to a variety of sources including the normative temporal expectations for the production of utterances through mouth-speech and the functioning of the device itself. The temporal misalignment leads to slippages in the participants’ orientation to the sequential relevance of utterances and utterance parts that leads to misunderstanding.
The Power of an Example: Hidden Set Size Approximation Using Group\n Queries and Conditional Sampling (2014)

We study a basic problem of approximating the size of an unknown set $S$ in a\nknown universe $U$. We consider two versions of the problem. In both versions\nthe algorithm can specify subsets $T\\subseteq U$. In the first version, which\nwe refer to as the group query or subset query version, the algorithm is told\nwhether $T\\cap S$ is non-empty. In the second version, which we refer to as the\nsubset sampling version, if $T\\cap S$ is non-empty, then the algorithm receives\na uniformly selected element from $T\\cap S$. We study the difference between\nthese two versions under different conditions on the subsets that the algorithm\nmay query/sample, and in both the case that the algorithm is adaptive and the\ncase where it is non-adaptive. In particular we focus on a natural family of\nallowed subsets, which correspond to intervals, as well as variants of this\nfamily.\n
An Atlas of Mars Sedimentary Rocks as seen by HIRISE (2012)

Abstract Images of distant and unknown places have long stimulated the imaginations of both explorers and scientists. The atlas of photographs collected during the Hayden (1872) expedition to the Yellowstone region was essential to its successful advocacy and selection in 1872 as America’s first national park. Photographer William Henry Jackson of the Hayden expedition captured the public’s imagination and support, returning home with a treasure of images that confirmed the existence of western landmarks previously regarded as glorified myths: the Grand Tetons, Old Faithful, and strange pools of boiling hot mud. Fifty years later, photographer Ansel Adams began his long legacy of providing the public with compilations of iconic images of natural wonders that many only see in prints. Photography in space has provided its own bounty. Who can forget the first image of Earthrise taken by astronaut William Anders in 1968 from Apollo 8; the solemnity of the first photos of the surface of the Moon from the Apollo 11 astronauts; and the startling discovery of the tallest mountain in the solar system (Olympus Mons) on the surface of Mars in images sent from Mariner 9? The images from Mariner 9 also allowed for a game-changing discovery. Earlier, based on very limited Mariner 4 data that covered less than 10% of the planet’s surface, Chapman et al. (1968) speculated that “If substantial aqueous erosion features—such as river valleys— were produced during earlier epochs of Mars, we should not expect any trace of them to be visible
Kinetics of thermal and acidic degradation of poly‐1,3‐dioxolane (1970)

Abstract The kinetics and parameters of thermal and acidic degradation of poly‐1,3‐dioxolane were investigated in order to elucidate the mechanism of degradation and to obtain information on the nature of active centers. Both homolytic and heterolytic breaking of a macromolecule were shown to be random and occur at the acetal bond. Thermal degradation was found to proceed in two stages, depending on temperature and involving active centers of a different nature, i.e., macroions and macroradicals. The rate‐determining step of thermal degradation appears to be one involving the radical component, similarly to thermal degradation of olefin polyoxides. Acidic degradation occurs solely by the depolymerization mechanism, as in the case of polyaldehydes. It was concluded that the degradation mechanism depends not only on the chain structure and the thermodynamic properties of the system, but also on the nature of active centers.
Advanced intervention planning for Transcatheter Aortic Valve Implantations (TAVI) from CT using volumetric models (2013)

Aortic valve stenosis is a serious heart disease affecting a large group of elderly people. Recently minimal invasive procedures, such as the Transcatheter Aortic Valve Implantation (TAVI), are beginning to substitute conventional surgical techniques. Current methods [1] can extract basic biomarkers for TAVI such as optimal C-arm angulations, area and diameter measurements. However as the most prevalent TAVI complications (stroke and paravalvular leakages) are correlated with calcium and leaflet interactions within the valve a more advanced solution is needed. We propose a fully integrated system to extract automatically the patient specific model of the aortic valve including the volumetric model of the aortic valve leaflets and calcium from high resolution single phase CT. Based on the volumetric model advanced clinical parameters can be derived and used for e.g. patient selection, paravalvular leakage prediction and patient stroke risk assessment. We employ robust machine learning algorithms to estimate the valve model parameters. A multi-class classification method is introduced to label regions of calcium, leaflet and blood pool within the aortic valve and extract volumetric models of the aortic valve leaflets. Extensive quantitative and qualitative experiments on 198 volumetric data sets demonstrate an accurate DICE similarity score, i.e. 0.7 for the aortic valve leaflets and 0.86 for calcium tissue. Within 6 seconds a complete patient-specific model of the aortic valve can be estimated.
Математическая модель реакции отверждения ЭД-20 с отвердителем ТЭАТ-1 (2019)

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KOMB: Graph-Based Characterization of Genome Dynamics in Microbial Communities (2020)

Abstract Characterizing metagenomic samples via kmer-based, database-dependent taxonomic classification methods has provided crucial insight into underlying host-associated microbiome dynamics. However, novel approaches are needed that are able to track microbial community dynamics within metagenomes to elucidate genome flux in response to perturbations and disease states. Here we describe KOMB, a novel approach for tracking homologous regions within microbiomes. KOMB utilizes K-core graph decomposition on metagenome assembly graphs to identify repetitive and homologous regions to varying degrees of resolution. K-core performs a hierarchical decomposition which partitions the graph into shells containing nodes having degree at least K, called K-shells, yielding O ( V + E ) complexity compared to exact betweenness centrality complexity of O ( V E ) found in prior related approaches. We show through rigorous validation on simulated, synthetic, and real metagenomic datasets that KOMB accurately recovers and profiles repetitive and homologous genomic regions across organisms in the sample. KOMB can also identify functionally-rich regions in Human Microbiome Project (HMP) datasets, and can be used to analyze longitudinal data and identify pivotal taxa in fecal microbiota transplantation (FMT) samples. In summary, KOMB represents a novel approach to microbiome characterization that can efficiently identify sequences of interest in metagenomes.
Solubility of Hydrocarbons and CO2 Mixtures in Water under High Pressure (1999)

New solubility data for methane, carbon dioxide, and their binary mixtures in pure water were obtained at 344.25 K and from 10 to 100 MPa. A thermodynamic model that combines a cubic equation of state (Peng−Robinson with kij given in the literature) with the Henry's law approach has been elaborated. It has been shown that the (P,T) functional form of Henry's constant given by the Krichevsky−Kasarnovsky equation is applicable. It involves two important parameters: partial molar volume at infinite dilution and Henry's constant at the vapor pressure of water. Neither of these two parameters is a function of pressure or composition. The Henry's constant correlations of Li and Nghiem and Harvey, and the partial molar volume correlation of Lyckman et al. have been validated using a great number of solubility data.
A 256 Mb SDRAM using a register-controlled digital DLL (2002)

This 256 Mb synchronous DRAM with 1 ns clock access is stable against temperature, voltage, and process variation by use of an innovative register-controlled delay locked loop (RDLL). Unlike most conventional high-density DRAMs, the bit-lines are placed above the storage capacitors in this DRAM to relax design rules of the core area. The noise issues are analyzed and resolved to help implement the technology in mass production of 0.28 to 0.24 /spl mu/m 200 MHz DRAMs.
Stream Aggregation Through Order Sampling (2017)

This paper introduces a new single-pass reservoir weighted-sampling stream aggregation algorithm, Priority-Based Aggregation (PBA). While order sampling is a powerful and efficient method for weighted sampling from a stream of uniquely keyed items, there is no current algorithm that realizes the benefits of order sampling in the context of stream aggregation over non-unique keys. A naive approach to order sample regardless of key then aggregate the results is hopelessly inefficient. In distinction, our proposed algorithm uses a single persistent random variable across the lifetime of each key in the cache, and maintains unbiased estimates of the key aggregates that can be queried at any point in the stream. The basic approach can be supplemented with a Sample and Hold pre-sampling stage with a sampling rate adaptation controlled by PBA. This approach represents a considerable reduction in computational complexity compared with the state of the art in adapting Sample and Hold to operate with a fixed cache size. Concerning statistical properties, we prove that PBA provides unbiased estimates of the true aggregates. We analyze the computational complexity of PBA and its variants, and provide a detailed evaluation of its accuracy on synthetic and trace data. Weighted relative error is reduced by 40% to 65% at sampling rates of 5% to 17%, relative to Adaptive Sample and Hold; there is also substantial improvement for rank queries.
10.1016/0967-0653(96)83370-9 (2000)

Abstract Hydrocarbon-utilizing microorganisms are ubiquitously distributed in the marine environment following oil spills. These microorganisms naturally biodegrade numerous contaminating petroleum hydrocarbons, thereby cleansing the oceans of oil pollutants. Bioremediation, which is accomplished by adding exogenous microbial populations or stimulating indigenous ones, attempts to raise the rates of degradation found naturally to significantly higher rates. Seeding with oil degraders has not been demonstrated to be effective, but addition of nitrogenous fertilizers has been shown to increase rates of petroleum biodegradation. In the case of the Exxon Valdez spill, the largest and most thoroughly studied application of bioremediation, the application of fertilizer (slow release or oleophilic) increased rates of biodegradation 3–5 times. Because of the patchiness of oil, an internally conserved compound, hopane, was critical for demonstrating the efficacy of bioremediation. Multiple regression models showed that the effectiveness of bioremediation depended upon the amount of nitrogen delivered, the concentration of oil, and time.
Oxidation induced magnetic and structural changes in magneto-optical alloys (1987)

The oxidation kinetics of unovercoated TbFeCo alloys at 70°C is studied utilizing Kerr, VSM and ESCA measurements. In this manner the effect of oxidation-induced compositional modification on magneto-optical properties of the alloy are investigated. It is determined that oxygen diffusion leads to the formation of a structure consisting of a matrix of an oxide of Tb within which metallic Fe and Co are encountered. The presence of this complex matrix severely modifies the overall properties of the alloy.
Structural and Spectral Features of Complex Salts Composed of [Ni(dmit)2]− and Four- or Six-Coordination Nickel(II) Complexes of Alkyl-Substituted Cyclam (2006)

Abstract Slow inter-diffusion of (NBu4)[Ni(dmit)2] (dmit = 2-thioxo-1,3-dithiole-4,5-dithiolato) and a metal complexes ligated with alkyl-substituted cyclam, [Ni(NMe2-dcyclam)](ClO4)2 (I), [Ni(NMe2-ax-dcyclam)](ClO4)2 (II), and [Ni(NMe4-dcyclam)]Cl2 (III), (NMe2-dcyclam = (1RS,4RS,5RS,8SR,11SR,12SR)-1,5,8,12-tetramethyl-1,4,8,11-tetraazacyclotetradecane, NMe2-ax-dcyclam = (1RS,4RS,5SR,8SR,11SR,12RS)-1,5,8,12–tetramethyl-1,4,8,11-tetraazacyclotetradecane, NMe4-dcyclam = (1RS,4RS,5RS,8SR,11SR,12SR)-1,4,5,8,11,12-hexamethyl-1,4,8,11-tetraazacyclotetradecane), yielded black crystals of [Ni(NMe2-dcyclam)(CH3CN)2][Ni(dmit)2]2 (1), [Ni(NMe2-ax-dcyclam)][Ni(dmit)2]2 (2), and [Ni(NMe4-dcyclam)][Ni(dmit)2]2 (3), respectively. In these complex salts, the cationic complex I adopted an octahedral six-coordination geometry with two molecules of acetonitrile occupying the trans coordination sites (structure A), while those of complexes II and III adopted a square-planar four-coordination geometry (structure B). The Ni–Ni distances between cation and anion in structure B were shorter than those of structure A. In the IR spectra, ν(C=S) of structure B was observed 10 cm−1 higher than that of structure A, and only in compound 2, ν(C=C) was split at 1346 and 1323 cm−1. Electric conductivities of compounds 1–3 were about 10−6 S cm−1 at room temperature behaving as semiconductors.
5-endo-trig Radical Cyclizations:  A New Means to the Stereoselective Synthesis of Cyclopentanes and Diquinanes (1996)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXT5-endo-trig Radical Cyclizations: A New Means to the Stereoselective Synthesis of Cyclopentanes and DiquinanesStéphane Bogen and Max MalacriaView Author Information Université Pierre et Marie Curie, Paris VI Laboratoire de Chimie Organique de Synthèse associé au CNRS, Tour 44-54, B. 229 4 Place Jussieu, 75252 Paris Cedex 05, France Cite this: J. Am. Chem. Soc. 1996, 118, 16, 3992–3993Publication Date (Web):April 24, 1996Publication History Received13 November 1995Published online24 April 1996Published inissue 24 April 1996https://pubs.acs.org/doi/10.1021/ja953806lhttps://doi.org/10.1021/ja953806lrapid-communicationACS PublicationsCopyright © 1996 American Chemical SocietyRequest reuse permissionsArticle Views969Altmetric-Citations56LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information SUBJECTS:Cyclization,Organic reactions,Redox reactions,Stereoselectivity,Vinyl Get e-Alerts
Humour in Chetan Bhagat’s The Girl in Room 105 and One Arranged Murder: A Study With Special Reference to His Creation of Dark Humour and Satire (2023)

Humour is the predominant element in all the novels of Chetan Bhagat. His novels contain ‘black humour’ which is a form of humour that presents sorrows and sufferings as very mean or that regards human existence as ironic and pointless but somehow comic. ‘Black humour’ is also called ‘Black Comedy’ or ‘Dark Humour’, and the idea that people are powerless victims of fate and character is frequently used to illustrate farce and low humour. The novelist uses humour to reflect the realistic picture of contemporary society. Humour can be more successful in one’s native language. Though the novelist writes in English, he uses very simple language which seems to be one’s own native tongue. The present paper is an attempt to explore humorous elements in Chetan Bhagat's most recent two novels, ‘The Girl in Room 105’ and ‘One Arranged Murder’, with special reference to black humour and satire.
Oral formulations of Metformin in semi-solid matrices: Design, characterization & in vitro evaluations (2015)

P To formulate and evaluate oral dosage forms of Metformin hydrochloride (MH) having sustained-release properties that would also increase MH bioavailability and address the shortcomings in the currently marketed sustainedrelease tablets.Methods. MH micronized powder was dispersed in molten polymeric matrices composed of Gelucire® 50/13 and various proportions of high molecular weight hydrophilic polymers, hydrophobic oily semisolid excipients, and mucoadhesive polymeric materials. The MH loaded matrices were filled in hard gelatin capsules (HGC) each containing 500 mg MH and were subsequently characterized using Differential Scanning Calorimetry (DSC) and X-Ray Diffraction Analysis (XRD). The prepared HGC were subjected to content uniformity and in vitro dissolution testing according to the USP-35 compendial requirements. The dissolution data were compared to instant and sustained-release marketed tablets. The effect of incorporating various proportions of the semisolid excipients on MH dissolution release rate, were also investigated.Results. MH content of the prepared HGC ranged between 96 to 103%. All the prepared semisolid filled HGC resulted in extendedrelease profiles of MH that lasted between 5 to 11 hours and demonstrated a release pattern which typically follows the release from mixes of triglycerides with polyethylene glycol esters of fatty acids. The incorporation of muco-adhesive excipients like Carbomer to the Gelucire® 50/13-MH semisolid matrices extended the release of MH from 5 hours initially to 9 hours as a result of the formation of a gel layer around the matrix. However, the incorporation of different hydrophilic excipients like PEG35000 and Gelucire® 44/14 along with the muco-adhesive excipients sustained the release of MH up to 11 hours. XRD analysis of the MH prepared matrices demonstrated minor changes in the crystalline nature of MH. Depending on the loading ratios and the nature of the semisolid matrices used, DSC analysis revealed the changes in MH crystallinity to be from 100 to 23 %.Conclusion. HGC formulated using semisolid matrices showed promising results in extending the release of MH. However, bioavailability studies to test the ability of such Gelucire based HGC of MH to improve its bioavailability and in vivo residence times are future plans. Acknowledgements: This work was made possible by a NPRP award [NPRP 09-795-3-215] to HM Younes from the Qatar National Research Fund (a member of The Qatar Foundation). The statements made herein are solely the responsibility of the authors.
Amycomicin is a potent and specific antibiotic discovered with a targeted interaction screen (2018)

The rapid emergence of antibiotic-resistant pathogenic bacteria has accelerated the search for new antibiotics. Many clinically used antibacterials were discovered through culturing a single microbial species under nutrient-rich conditions, but in the environment, bacteria constantly encounter poor nutrient conditions and interact with neighboring microbial species. In an effort to recapitulate this environment, we generated a nine-strain actinomycete community and used 16S rDNA sequencing to deconvolute the stochastic production of antimicrobial activity that was not observed from any of the axenic cultures. We subsequently simplified the community to just two strains and identified <i>Amycolatopsis</i> sp. AA4 as the producing strain and <i>Streptomyces coelicolor</i> M145 as an inducing strain. Bioassay-guided isolation identified amycomicin (AMY), a highly modified fatty acid containing an epoxide isonitrile warhead as a potent and specific inhibitor of <i>Staphylococcus aureus</i> Amycomicin targets an essential enzyme (FabH) in fatty acid biosynthesis and reduces <i>S. aureus</i> infection in a mouse skin-infection model. The discovery of AMY demonstrates the utility of screening complex communities against specific targets to discover small-molecule antibiotics.
Evaluation of Low Saline “Smart Water” Enhanced Oil Recovery in Light Oil Reservoirs (2014)

With the depletion of natural driving forces responsible for pushing the oil from reservoirs & declination of oil recovery after secondary stage, the emphasis is now on EOR techniques. The low saline flooding is a type of EOR which gains the attention of researchers due to its easiness to use implications, less cost & environment-friendly nature. Though the low salinity effect has been seen in various labscale core flooding experiments as well as field pilot projects, the mechanism which actually leads to this enhancement in recovery is still the area of research among researchers which is wide open and needs to gain consensus. Seeing the wide mechanisms taking place under different scenarios, it is certain that more than one mechanism is actually supplementing each other in reducing the residual oil saturation while LSW flooding. This study has been undertaken investigations on the low saline flooding in unconsolidated Ottawa sandpack cores with two different, Weyburn & Pelican crude oil, to find out the optimum salinity, LSW Slug Size & underlying mechanisms during LSW flooding. Several core flooding experiments were performed under secondary as well as tertiary recovery stage by unsteady state method. With the reduction of brine salinity from 5000 PPM to 1500 PPM, the oil recovery increased in secondary stage & decreased further upon reduction in salinity to 500 PPM gaining the peak at 1500 PPM. Small enhancement in tertiary recovery of 2.24% observed upon switching to 1500 NaCl PPM brine after injection of formation brine in secondary stage for Weyburn Oil, though large tertiary recoveries of the order of 9.95% for effective oil viscosity of 4 cP and 7.32% for 29.7 cP were observed for n-dodecane diluted Pelican Oil. LSW slug size of 25% pore volume was found to be effective in producing Weyburn Oil in secondary stage.