gebhart/patrepeval huggingface dataset:
Experiments on PAVIN platform for cooperative inter-vehicle communication protocol (CIVIC) (2009)

This paper describes a cooperative MANET protocol dedicated to intelligent transportation systems and its new experiment results in mobile scenarios. The protocol is named CIVIC (Communication Inter Véhicule Intelligente et Coopérative). It is an auto-configuration inter-vehicle communication protocol, which supports ad-hoc and infrastructure networks, contains reactive and proactive routing components, and adapts different wireless standards. It is also a location-based and context-aware protocol reacting to vehicle status, road traffic, and geographic environment. The CIVIC protocol has been implemented on the LiveNode sensor developed by our laboratory. The new experiments of CIVIC protocol are carried out on PAVIN platform (Plate-forme d'Auvergne pour Véhicules Intelligents) supported by the TIMS (Technologies de l'Information de la Mobilité et de la Sûreté) research federation. These experiments demonstrate the feasibility and reliability of CIVIC in mobility scenarios. In addition, an application project named MobiPlus will be introduced.
Donor CD8+ T cells facilitate induction of chimerism and tolerance without GVHD in autoimmune NOD mice conditioned with anti-CD3 mAb (2004)

Prevention of autoimmune diabetes and induction of islet transplantation tolerance in nonobese diabetic (NOD) mice can be reached by induction of mixed chimerism via bone marrow transplantation (BMT), but this procedure requires total body irradiation (TBI) conditioning of the recipients. The toxicity of radiation and potential for graft-versus-host disease (GVHD) prevents its clinical application. Donor CD8+ T cells play a critical role in facilitation of engraftment but also contribute to induction of GVHD in TBI-conditioned recipients. Here, we showed that high doses of donor CD8+ T cells in combination with bone marrow (BM) cells induced mixed chimerism without GVHD in NOD recipients conditioned with anti-CD3 monoclonal antibody (mAb). The prevention of GVHD in those recipients was associated with low-level production of inflammatory cytokines (ie, tumor necrosis factor alpha [TNF-alpha]), high-level production of anti-inflammatory cytokines (ie, interleukin 4 [IL-4] and IL-10), and confining of the donor CD8+ T-cell expansion to lymphohematopoietic tissues. The chimeric NOD recipients showed donor-specific tolerance and reversal of insulitis. These results demonstrate that donor CD8+ T-cell-mediated facilitation of engraftment can be separated from GVHD in nonirradiated recipients. This regimen may have potential application in the treatment of autoimmune disorders as well as induction of transplantation tolerance.
Directing vanillin production from ferulic acid by increased acetyl‐CoA consumption in recombinant Escherichia coli (2008)

The amplification of gltA gene encoding citrate synthase of TCA cycle was required for the efficient conversion of acetyl-CoA, generated during vanillin production from ferulic acid, to CoA, which is essential for vanillin production. Vanillin of 1.98 g/L was produced from the E. coli DH5alpha (pTAHEF-gltA) with gltA amplification in 48 h of culture at 3.0 g/L of ferulic acid, which was about twofold higher than the vanillin production of 0.91 g/L obtained by the E. coli DH5alpha (pTAHEF) without gltA amplification. The icdA gene encoding isocitrate dehydrogenase of TCA cycle was deleted to make the vanillin producing E. coli utilize glyoxylate bypass which enables more efficient conversion of acetyl-CoA to CoA in comparison with TCA cycle. The production of vanillin by the icdA null mutant of E. coli BW25113 harboring pTAHEF was enhanced by 2.6 times. The gltA amplification of the glyoxylate bypass in the icdA null mutant remarkably increased the production rate of vanillin with a little increase in the amount of vanillin production. The real synergistic effect of gltA amplification and icdA deletion was observed with use of XAD-2 resin reducing the toxicity of vanillin produced during culture. Vanillin of 5.14 g/L was produced in 24 h of the culture with molar conversion yield of 86.6%, which is the highest so far in vanillin production from ferulic acid using recombinant E. coli.
Resilient Digital Twins (2021)

Currently, we can witness contradictory expectations when it comes to IT. On the one hand, there is the belief that Artificial Intelligence (AI) and Machine Learning (ML) will solve most problems because of the abundance of data and sophisticated algorithms In this editorial, we use AI/ML to refer to machine intelligence, i.e., mixtures of Artificial Intelligence and Machine Learning. AI/ML can deal amazingly well with unstructured data (text, images, and video) as long as there are enough training data. On the other hand, the COVID-19 pandemic and rapid climate changes (e.g., the floods in Germany in July 2021) show that AI/ML cannot deal with disruptions. When there is a sudden dramatic change, predictive models will fail, no matter how much data was there before. Consider, for example, the impact of the COVID-19 pandemic on supply chains. Especially at the beginning of the global outbreak of COVID-19 in March 2020, supply chains failed because of the unpredicted demand for certain products (e.g., masks and toilet paper) combined with simultaneous restrictions for travel, work, and business.
Characterization study of GaAs(001) surfaces using ion scattering spectroscopy and x-ray photoelectron spectroscopy (1997)

A surface characterization study using ion scattering spectroscopy (ISS) and x-ray photoelectron spectroscopy (XPS) has been performed on solvent cleaned, n-type GaAs(001) substrates before and after cleaning by ion sputtering and annealing. The native oxide layer on this surface contains large amounts of As2O5,As2O3, and Ga2O3 according to XPS with Ga2O3 being the predominant species. Before cleaning C is present as hydrocarbons, carbonates, and carbide with hydrocarbons as the predominant chemical state. Ion sputtering converts the hydrocarbons into carbide, which is difficult to remove by further sputtering/annealing cleaning cycles, but O is removed by these cycles. According to ISS data, the outermost atomic layer is enriched in Ga before cleaning, but after cleaning the ISS Ga-to-As atom ratio is about 1:2. The results obtained in this study are consistent with the presence of a layered oxide structure with Ga2O3 just above the interface. A sputter-cleaned surface initially exhibits an increase in the Ga-to-As surface atom ratio which returns to the initial state with time (∼2 h) as observed by ISS. The Ga-to-As surface atom ratio also increases by annealing at temperatures as low as 180 °C.
Microwave and Tween-80 Assisted Hydrothermal Synthesized of BiVO<sub>4</sub> and its Improved Photo Catalytic Activity under Visible Light (2016)

Monoclinic BiVO 4 nanosheets were successfully synthesized by the microwave hydro-thermal method in a relatively short time with TW-80(C 64 H 124 O 26 -80) acted as the soft template. The effect of pH, synthesizing time on the morphology, and dosage of TW-80 were investigated in detail. The crystal form, morphology and absorption spectrum of the as prepared BiVO 4 samples were characterized by means of x-ray diffraction (XRD), scanning electron microscopy (SEM), UV-vis diffuse reflectance spectroscopy (DRS) respectively. The experimental results demonstrated that the samples synthesized both under acid and neutral environment showed the higher photo-catalytic activity. Up to 98% of MB was degraded in 300 minutes. The certain amount of TW-80 added in synthesizing BiVO 4 altered the morphology, resulted in the appearance of more active sites, shortened the transmittance distance of the carriers and thus enhanced photo-induced electrons separation efficiency.
Anti‐EBNA‐1 IgG is not a reliable marker of multiple sclerosis clinical disease activity (2010)

We have been unable to determine a clinical value for serum anti-EBNA-1 IgG levels in MS or to confirm reported association with disease course and clinical disease activity.
Coupled Vehicle Design and Network Flow Optimization for Air Transportation Systems (2007)

be obtained by concurrently optimizing the vehicle design and network flow. This is accomplished by embedding a linear programming solver in the perturbation step of simulated annealing to solve for the large number of linear constraints imposed by the capacity and demand requirements of the network. The benefits of this new formulation are illustrated through an example of an air transportation system for an overnight package delivery network in which a 10% improvement in cost is obtained over traditional network flow optimization. The improvement in system cost obtained can be attributed to the reduction in operational inefficiencies for the transportation system.
Significant elevation of a Th2 cytokine, interleukin-10, in pelvic inflammatory disease (2008)

The results indicate that the imbalance and cross-regulation between Th1 and Th2 cytokines pathways is probably contributed to the mechanism of PID.
Influence of total nucleated cell dose from marrow harvests on outcome in patients with acute myelogenous leukemia undergoing autologous transplantation. (1995)

This retrospective study was conducted to determine whether the total number of nucleated cells (TNC)/kg collected at marrow harvest was associated with outcome in 151 patients with acute myelogenous leukemia (AML) who received an autologous purged (n = 67) or non-purged (n = 84) marrow transplant. At the time of transplant 33 patients were in first complete remission (CR), 47 in second CR, 54 in first relapse and 17 beyond second CR. Ninety patients received busulfan (BU) 16 mg/kg and cyclophosphamide (CY) 120 or 200 mg/kg, 51 patients received CY 120 mg/kg and total body irradiation (TBI) 12-15.75 Gy and 10 patients received BU 8 mg/kg, CY 60 mg/kg and TBI 12 Gy as conditioning regimens. Patients whose marrow harvest yielded < 2 x 10(8) TNC/kg did not undergo purging with 4-hydroperoxycyclophosphamide (4HC). This group of patients (n = 28) had a 100 day mortality of 50% and only 54% achieved a granulocyte levels of > 0.5 x 10(9)/l and 29% achieved platelet transfusion independence. Patients whose marrow harvest yielded 2-4 x 10(8) TNC/kg and did not undergo marrow purging had a 20% mortality by day 100, 91% recovered granulocytes to > 0.5 x 10(9)/l and 61% became platelet independent. Patients whose marrow harvest yielded 2-4 x 10(8) TNC/kg and underwent marrow purging with 4HC had a 50% mortality by day 100 and 58% achieved a granulocyte levels of > 0.5 x 10(9)/l and 42% became platelet transfusion independent.(ABSTRACT TRUNCATED AT 250 WORDS)
Raytraced rendering using t-buffer and shadow-buffer (2004)

Ray-tracing is one of the most researched areas in 3D photo-realistic image synthesis. We propose the T-BUFFER algorithm, which is a modification to the conventional ray-tracing algorithm and compares very favorably with it in terms of performance, which is achieved primarily through reduction in the number of unsuccessful intersection tests. Our major contribution is the integration of a shadow-buffering technique which, in conjunction with the t-buffer, can create ray-traced renderings with reasonably accurate shadows much more efficiently than the common approach, while giving the user control over the quality of shadows and the related computational efficiency. We support the above claims with empirical evidence which suggest an approximately linear gain over the original ray-tracing algorithm. We also describe REALITY – a complete rendering engine which has been developed for the purpose of empirical comparison between the T-BUFFER algorithm and the classical ray-tracing algorithm. Both algorithms were implemented in a common code base to facilitate direct comparison. The engine also implements the above mentioned shadow-buffering technique to accelerate shadow calculations. We present a thorough comparative analysis of the original algorithm and the T-BUFFER algorithm, based on the rendering times of REALITY and show that the results strongly corroborate with the linear gain expected theoretically.
Abstract 19080: Peak Exercise Capacity is a Poor Indicator of Functional Capacity for Patients Supported by a Continuous Flow Left Ventricular Assist Device (2013)

Introduction: Six minute walk distance (6MWD) has been shown to be linearly related to peak oxygen uptake (VO2) during maximal exercise for patients suffering from heart failure (HF); however, this relationship in patients supported by left ventricular assist devices (CF-LVAD) is not well understood. Hypothesis: CF-LVADs readily support sub-maximal exercise such as walking, but this improvement is not accompanied by increased maximal exercise capacity due to relatively fixed cardiac output assistance provided by the LVAD. Methods: Forty patients with HF and 29 patients supported by LVADs performed a 6-minute walk test and a maximal cardiopulmonary exercise test. Results: The peak VO2 was linearly correlated with 6MWD in both HF (r=0.58, p&lt;0.001) and LVAD patients (r=0.53, p=0.003). While the slopes were similar, b=0.025 and b=0.029 for CHF and LVAD, respectively, patients with HF had a greater peak VO2 than patients supported by LVADs who achieved the same 6MWD. CF-LVAD patients walked approximately 80 meters more than HF patients in a 6-minute walk test for any given peak VO2. Conclusions: For any given peak VO2, patients supported by LVAD may have a greater functional capacity than HF patients. Peak VO2 should not be used as an outcome variable in clinical trials assessing functional capacity after LVAD implantation.
Viscous interactions of many neutrally buoyant spheres in Poiseuille flow (1986)

A theory is developed to predict the motion of N neutrally buoyant spheres suspended in laminar flow between parallel plates. The spheres are at large separation yet nearer each other than the duct walls, and the Reynolds number is small. In this parameter range, viscous interactions are larger than inertial effects, and can be represented in terms of a superposition of ‘strainlets’. Several examples are given to show this viscous interaction effect. Near the leading edge of a front of spheres or near the trailing edge significant lateral migration velocities can occur, being at least one order of magnitude larger than inertially induced migration velocities. This phenomenon may have a negative effect on ‘chromatographic’ separation schemes, affecting particle concentration, recovery and resolution.
Organocopper Conjugate Addition-Enolate Trapping Reactions (1985)

Conjugate additions reactions between organocopper reagents and α,β-unsaturated carbonyl compounds are now well established synthetic procedures. This article reviews reactions in which the intermediate enolates are trapped with electrophilic reagents to give β-substituted enol derivatives or α,β-disubstituted ketones. The synthetic potential of these products is highlighted. 1. Introduction: Scope and Limitations 2. Silylation and Related O-Enolate Trapping Reactions 3. Enolate Acylation 4. Enolate Alkylation 5. Reactions of Enolates with Michael Acceptors 6. Reactions of Enolates with Aldehydes and Ketones 7. Reactions of Enolates with Miscellaneous Non-Carbon Electrophiles 8. Recent Results 9. Conclusions
Cardiovascular risk assessment using ASCVD risk score in fibromyalgia: a single-centre, retrospective study using “traditional” case control methodology and “novel” machine learning (2021)

FM patients of the 40-59 years age group had increased lifetime CVD risk in our study. Although FM disease severity was not associated with high CVD risk as per the conventional statistical analysis of the data, it was among the highest contributor to ML predictive model for CVD risk in FM patients. This also highlights that ML can potentially help to bridge the gap of non-linear risk factor identification.
Effect of a Specialized Amino Acid Mixture on Human Collagen Deposition (2002)

Collagen synthesis is significantly enhanced in healthy elderly volunteers by the oral administration of a mixture of arginine, HMB, and glutamine. This provides a safe nutritional means for increasing wound repair in patients.
Human Lens Capsule Thickness as a Function of Age and Location along the Sagittal Lens Perimeter (2006)

The human lens capsule thickness is at its maximum at the anterior midperiphery, which appears to be located central to the zonular insertion. It increases with age, especially at the anterior pole, while the midperipheral zone stabilizes or slightly decreases after the seventh decade. The anterior zonular insertion is actually related to a local pre-equatorial thinning, which remains unchanged with age. There was no posterior peripheral thickening, except in a few younger patients, with a modest relative maximum roughly at the equator. From here, the posterior capsule becomes progressively thinner and also diminishes with age, except for the thinnest, but stable posterior pole.
Radiometric calibration stability assessment for the RISAT-1 SAR sensor using a deployed point target array at the Desalpar site, Rann of Kutch, India (2017)

Synthetic aperture radar (SAR) data used for quantitative temporal and/or spatial analysis requires calibration to ensure that observed pixel values of amplitude and phase can be related to the geophysical parameters of interest. The process of radiometric calibration of SAR images involves comparison of the backscattered radar reflectivity signal from a ground resolution element containing a calibration target of known signal response, such as a corner reflector. In this study, absolute radiometric calibration of RISAT-1 intensity data of fine resolution stripmap-1 (FRS-1) and medium resolution ScanSAR (MRS) mode was carried out by utilizing array of standard point targets of various types (triangular trihedral, square trihedral, and dihedral) with known radar cross-section deployed prior to satellite overpass with precise azimuth and elevation angles in Desalpar, Rann of Kutch in western India. The derived calibration constants using the integral method were then compared with the values provided in the header file. Deviations in the results are reported in this article. The results obtained show that the difference between the estimated average calibration constants for FRS-1 and MRS mode data with the provided value was found to be within the absolute radiometric accuracy specification of Radar Imaging SATellite (RISAT-1). Near-range to far-range difference of 0.1–0.2 dB for HH (Horizontal transmit, Horizontal receive) polarization and 0.1–0.3 dB for HV (Horizontal transmit, Vertical receive) polarization was estimated for the same scene using distributed target analysis indicating the stability of calibration for the same scene. This study also concluded that Desalpar site in Rann of Kutch has the potential of being an operational SAR calibration site.
Some Effects of Trypsin and Streptokinase on Platelet Aggregation (1967)

Summary The effect of the proteolytic enzymes trypsin and streptokinase on platelet aggregation were investigated using the turbidimetric system of Born and the Chandler tube system. The following results were obtained : 1. ADP and adenosine display a similar action in the Chandler tube system as in the turbidimetric system. 2. Platelet aggregation is accelerated in the Chandler tube system by trypsin over a range of concentrations 10 µg/ml to 1 mg/ml and in the turbidimetric system over a range of concentrations 100 µg/ml to 1 mg/ml. 3. Streptokinase, at low concentrations, enhances aggregation in the Chandler tube system but plasma antiplasmin must be destroyed before a similar effect is observed in the turbidimetric system. 4. The results obtained with trypsin cannot be accounted for solely on the basis of its coagulant action.
Low Inflammatory Activation by Self‐Assembling Rosette Nanotubes in Human Calu‐3 Pulmonary Epithelial Cells (2008)

Rosette nanotubes (RNT) are a new class of metal-free organic nanotubes synthesized through self-assembly. Because of the wide range of potential biomedical applications associated with these materials, it is necessary to evaluate their potential in vitro toxicity. Here the cytotoxicity of a lysine-functionalized nanotube (RNT-K) in a human Calu-3 pulmonary epithelial cell line is investigated. The cells were treated with media only (control), lysine (50 mg mL(-1)), RNT-K (1, 5, and 50 microg mL(-1)), Min-U-Sil quartz microparticles (QM; 80 microg mL(-1)), and lipopolysaccharide (LPS; 1 microg mL(-1)). The supernatants were analyzed at 1, 6, and 24 h after treatment for the expression of three proinflammatory mediators: IL-8, TNF-alpha and EMAP-II. Cellular viability determined with the Trypan blue assay is significantly reduced in the QM and high-dose RNT-treated groups. TNF-alpha and EMAP-II are undetectable by enzyme-linked-immunosorbent assay (ELISA) in the supernatant of all groups. Although IL-8 concentrations do not differ between treatments, its concentrations increase with time within each of the groups. Quantitative reverse-transcriptase polymerase chain reaction (qRTPCR) of IL-8 mRNA shows increased expression in the high-dose RNT-treated groups at both 1 and 6 h, while an adhesion molecule, ICAM-1 mRNA, shows the greatest increase at 6 h in the QM-treated group. In summary, RNT-K neither reduces cell viability at moderate doses nor does it induce a time-dependent inflammatory response in pulmonary epithelial cells in vitro.
[First year experience using arabin cervical pessary with intravaginal micronized progesterone for the prevention of preterm birth in patients with mid-trimester short cervix]. (2014)

The use of cervical pessary in conjunction with intravaginal progesterone is safe and feasible. Patients with twin pregnancies had a significantly higher rate of preterm birth compared to singleton pregnancies. Further research is needed to assess device efficacy.
0-1 Quadratic programming approach for optimum solutions of two scheduling problems (1994)

Two scheduling problems are considered: (1) scheduling n jobs non-preemptively on a single machine to minimize total weighted earliness and tardiness (WET); (2) scheduling n jobs non-preemptively on two parallel identical processors to minimize weighted mean flow time. In the second problem, a pre-ordering of the jobs is assumed that must be satisfied for any set of jobs scheduled on each specific machine. Both problems are known to be NP-complete. A 0-1 quadratic assignment formulation of the problems is presented. An equivalent 0-1 mixed integer linear programming approach for the problems are considered and a numerical example is given. The formulations presented enable one to use optimal and heuristic available algorithms of 0-1 quadratic assignment for the problems considered here.