gebhart/patrepeval huggingface dataset:
Intraoperative 5-fluorouracil for filtration surgery in the rabbit. (1993)

Intraoperative application of high-dose 5-FU to the filtration site either as a single 5-minute treatment, or in conjunction with postoperative injections of 5-FU greatly prolongs bleb function after filtration surgery in the rabbit.
Fiberoptic Bronchoscopic Treatment of Pulmonary Aspiration Occurring in a Child during Induction of Anesthesia: A case report (2005)

(pulmonary aspiration) . 1) , , , , , . 2,3)
Efficient parallel optimization for potts energy with hierarchical fusion (2015)

Potts energy frequently occurs in computer vision applications. We present an efficient parallel method for optimizing Potts energy based on the extension of hierarchical fusion algorithm. Unlike previous parallel graph-cut based optimization algorithms, our approach has optimality bounds even after a single iteration over all labels, i.e. after solving only k-1 max-flow problems, where k is the number of labels. This is perhaps the minimum number of max-flow problems one has to solve to obtain a solution with optimality guarantees. Our approximation factor is O(log <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> k). Although this is not as good as the factor of 2 approximation of the well known expansion algorithm, we achieve very good results in practice. In particular, we found that the results of our algorithm after one iteration are always better than the results after one iteration of the expansion algorithm. We demonstrate experimentally the computational advantages of our parallel implementation on the problem of stereo correspondence, achieving a factor of 1.5 to 2.6 speedup compared to the serial implementation. These results were obtained with a small number of processors. The expected speedups with a larger number of processors are greater.
Inhibition of monocyte-derived inflammatory cytokines by IL-25 occurs via p38 Map kinase–dependent induction of Socs-3 (2009)

IL-25, a member of the IL-17 cytokine family, is known to enhance Th2-like responses associated with increased serum levels of IgE, IgG1, IgA, blood eosinophilia, and eosinophilic infiltrates in various tissues. However, IL-25 also abrogates inflammatory responses driven by Th17 cells. However, the cell types that respond to IL-25 and the mechanisms by which IL-25 differentially regulates immune reactions are not well explored. To identify potential targets of IL-25, we initially examined IL-25 receptor (IL-25R) in human peripheral blood cells. IL-25R was predominantly expressed by CD14(+) cells. We next assessed the functional role of IL-25 in modulating the response of CD14(+) cells to various inflammatory signals. CD14(+) cells responded to IL-25 by down-regulating the synthesis of inflammatory cytokines induced by toll-like receptor (TLR) ligands and inflammatory cytokines. Inhibition of cytokine response by IL-25 occurred via a p38 Map kinase-driven Socs-3-dependent mechanism. In vivo, IL-25 inhibited monocyte-derived cytokines and protected against LPS-induced lethal endotoxemia in mice. These data indicate that IL-25 is a negative regulator of monocyte proinflammatory cytokine responses, which may have therapeutic implications.
Degraded Compound Multi-receiver Wiretap Channels (2009)

In this paper, we study the degraded compound multi-receiver wiretap channel. The degraded compound multi-receiver wiretap channel consists of two groups of users and a group of eavesdroppers, where, if we pick an arbitrary user from each group of users and an arbitrary eavesdropper, they satisfy a certain Markov chain. We study two different communication scenarios for this channel. In the first scenario, the transmitter wants to send a confidential message to users in the first (stronger) group and a different confidential message to users in the second (weaker) group, where both messages need to be kept confidential from the eavesdroppers. For this scenario, we assume that there is only one eavesdropper. We obtain the secrecy capacity region for the general discrete memoryless channel model, the parallel channel model, and the Gaussian parallel channel model. For the Gaussian multiple-input multiple-output (MIMO) channel model, we obtain the secrecy capacity region when there is only one user in the second group. In the second scenario we study, the transmitter sends a confidential message to users in the first group which needs to be kept confidential from the second group of users and the eavesdroppers. Furthermore, the transmitter sends a different confidential message to users in the second group which needs to be kept confidential only from the eavesdroppers. For this scenario, we do not put any restriction on the number of eavesdroppers. As in the first scenario, we obtain the secrecy capacity region for the general discrete memoryless channel model, the parallel channel model, and the Gaussian parallel channel model. For the Gaussian MIMO channel model, we establish the secrecy capacity region when there is only one user in the second group.
Development and Characterization of an H-Shaped Microresonator Exhibiting 2:1 Internal Resonance (2017)

This paper reports on the design and characterization of an H-shaped microresonator exhibiting nonlinear modal interactions due to 2:1 internal resonance. This has been made possible through careful design of the structure with attention to the limits of microfabricated devices. The intended nonlinear dynamics rely on the continuous transfer of energy between the anti-phase motions of two H-like proof masses of the device to a mode along the orthogonal direction. Finite element and reduced order models of the structure were developed and used to design the devices with two desired flexural modes in a ~2:1 frequency ratio. The microresonator was fabricated in a commercial foundry process. Extensive experiments and transient simulations were conducted to verify the desired nonlinear responses and the models. It was demonstrated that the low-frequency mode of the device was excited through auto-parametric excitation of the higher frequency mode when the excitation level exceeded a specific threshold as expected. The device design methodologies can be employed to fabricate various sensors, including nonlinear Coriolis vibratory gyroscopes incorporating 2:1 internal resonance.
SYNTHESIS OF NEW 5-N-PYRAZOLYL AMINO ACIDS, PYRAZOLOPYRIMIDINES AND PYRAZOLOPYRIDINES DERIVATIVES (2015)

Reaction of ketene derivatives (1a,b) on treatment with 4-amino-1-phenyl-2,3-dimethyl pyrazolin-5-one gives compounds (2a,b) which react with hydrazine to afford 1-phenyl-2,3 dimethyl-4-[3-(5-amino-4-substituted)-1H-pyrazolylamino]pyrazolin-5-one (3a,b). Compounds (3a,b) on treatment with Boc. amino acids derivatives, acetic anhydride, ethyl acetoacetate and aldehydes afforded (4a-h), (5a-h), (6-10), (11a,b), respectively. Interaction of (9) or (10) with acetohydrazide, hydrazines, and then with p-bromobenzaldehyde afforded compounds (13), (14a,b) and (15), respectively. Interaction of (3a) with thioglycollic acid afforded pyrazolopyridines derivatives ( 16).
Wavefront shaping in underwater with soft gradient-index metasurfaces at ultrasonic frequencies (2020)

International audience
Use of Herbal Coagulant for PrimaryTreatment of Dairy Wastewater (2006)

Moringa Oleifera herbal coagulant is reported to be efficient in removal of turbidity from waters. Possibility of its use in the primary treatment of industrial wastewater was explored and the findings are reported in this paper. Dairy wastewater which was subjected to preliminary treatment - screens, oil and grease removal and equalization - aeration tank - was observed to contain white colloidal suspensions, mostly organic in nature. Coagulation-sedimentation studies were conducted on laboratory scale treatment units (Jar Test apparatus) using Moringa oleifera, a herbal coagulant, which is free of constraints viz. pH and alkalinity. The results of the studies are quite encouraging. Optimum dose of Moringa oleifera (60 mg/L) observed to reduce pollution parameters- initial BOD5 and COD of Dairy wastewater- to the tune of 55% and 60% respectively. Using fullers earth as coagulant-aid (15 mg/L) these reductions were further increased by 5% and 6% respectively. Preliminary and primary treatment together reduce the initial BOD5 and COD values respectively by 60 % and 66 % and residual BOD5 remained below 500 mg/L (maximum limit allowed for discharge of treated effluent on land through irrigation)
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data (2013)

The International Mouse Phenotyping Consortium (IMPC) web portal (http://www.mousephenotype.org) provides the biomedical community with a unified point of access to mutant mice and rich collection of related emerging and existing mouse phenotype data. IMPC mouse clinics worldwide follow rigorous highly structured and standardized protocols for the experimentation, collection and dissemination of data. Dedicated 'data wranglers' work with each phenotyping center to collate data and perform quality control of data. An automated statistical analysis pipeline has been developed to identify knockout strains with a significant change in the phenotype parameters. Annotation with biomedical ontologies allows biologists and clinicians to easily find mouse strains with phenotypic traits relevant to their research. Data integration with other resources will provide insights into mammalian gene function and human disease. As phenotype data become available for every gene in the mouse, the IMPC web portal will become an invaluable tool for researchers studying the genetic contributions of genes to human diseases.
Secondary Certificate Authentication in HTTP/2 (2017)

A use of TLS Exported Authenticators is described which enables HTTP/2
clients and servers to offer additional certificate-based credentials
after the connection is established. The means by which these
credentials are used with requests is defined.
Canonical views in procedural graphics (2003)

Canonical (three-quarter) views for procedural graphics have been advocated based on artistic practice and psychological research. This paper examines two alternate points of view: body-centered rear views, and views that place important distances across the display plane. Test subjects matched upright with overhead images of human bodies for two types of activities. The subjects' performance was measured for accuracy, confidence in making matches, and reaction time. The data suggest that, though canonical views may be optimal for illustration of objects, views that place important distances across the display plane may yield better performance for procedures involving human bodies.
MR COMPATIBLE OPTICAL MOTION TRACKING - Building an Optical Tracking System for Head Motion Compensation in MRI (2010)

Magnetic Resonance Imaging (MRI), in spite of its potential in medical diagnosis, has one major drawback: Image acquisition is a slow process, requiring the patient to not move for several minutes. This renders MRI useless in a number of cases. In the case of MR Imaging of the Head, optical motion tracking can be used for motion compensation, thereby greatly improving image quality. In this paper, an MR-compatible approach of tracking the patient's head is presented which does not require his or her cooperation, based on stereo-optical marker tracking. It is adapted to work in the MRI scanner, does not influence the MR image acquisition and is easily integrated into clinical routine.
On the Zigzag Form of Charged Domain Walls (1979)

Unusual domain walls have been found in ferrofluid patterns on thin film materials with low magnetization that is in or near the plane of the film. These walls carry a net magnetic charge and are characteristically kinked in a regular manner to form a zigzag. A simple account is given of the energetics of such walls whose form follows from a compromise between magnetostatic terms and the energy of anisotropy. It is argued that an array of closure domains at straight edges in these materials should have a boundary of similar character, and these too have been observed.
The influence of interfacial water on non-mechanical adhesion of copper sulphide and copper coatings to impact-resistant polystyrene (1994)

The influence of the storage time on the adhesion of CuS and electroless copper coatings to impact-resistant polystyrene (IRP) has been investigated. Adhesion of a non-mechanical nature was obtained by combining a surface treatment of IRP at room temperature in a xylene emulsion and a short-term (10 s) treatment at room temperature in a H2SO4-CrO3 solution. The adhesion value is close to zero immediately after depositing CuS and Cu coatings. However, the adhesion value increases with the storage time and the peel value of the coatings (P) becomes limited by the polymer's cohesive strength. The increase in adhesion in the course of exposure of the sample to the air is the result of water removal from the coating-polymer interface. It has been shown that besides evaporation, interfacial water may be removed from the interfacial region by interfacial forces, most likely of physical nature.
Overall survival estimates (landmark survival analysis) from Hyperprogressive Disease Is a New Pattern of Progression in Cancer Patients Treated by Anti-PD-1/PD-L1 (2023)

&lt;p&gt;*HPD adapted RECIST classes: complete response (CR), partial response (PR) and stable disease (SD) remained as defined by RECIST 1.1. Regarding progressive disease patients, these were allocated to PD non-HPD and to HPD. HPD patients are defined as progressive disease (PD) by RECIST 1.1 at the first evaluation and an increase {greater than or equal to} two-fold in the TGR EXPERIMENTAL compared to REFERENCE period.&lt;/p&gt;
Testing While Underbalanced Drilling: Horizontal Well Permeability Profiles (1999)

Abstract Underbalanced drilling has gained popularity during the last years as it is well-suited to the drilling of low-pressured reservoirs and provides a method to prevent formation damage, especially in horizontal wells. The production rate of formation fluids during drilling carries information on reservoir characteristics. In particular, the permeability profile along the well may be inferred from a combination of well pressure and total rate. The transient well inflow can be interpreted as a complex well test. The complexity arises from the fact that the boundary conditions (i.e. the well trajectory open to flow) change with time during the test. Moreover, the transient rate is influenced by variation in underbalance (i.e. well pressure) and well penetration rate. However, the signal (transient rate) carries detailed information on the permeability profile along the well. Analysis is preceded by the elimination of the effects of the variable underbalance and drill speed using deconvolution techniques. An accurate approximation of the permeability profile can be obtained by a direct analysis (i.e. without having to resort to history matching) of the corrected well influx. Note that only the total well rate trqnsient is required rather than the full inflow profile along the open well trajectory. In previous work we considered the analysis of the transient rate during underballanced drilling of a vertical well under a constant underbalance. Both the variable underbalance and the more complex outer boundary conditions of a horizontal well (the transient is very likely to see the cap-and base-rock boundaries during the test) distinguish the current study from the previous one.
Comparison of Superconducting Transition Characteristics of Two Iridium/Gold Bilayer Transition Edge Sensor Devices (2004)

We are developing a high-energy-resolution X-ray microcalorimeter for X-ray fluorescent spectrometry using a superconducting transition edge sensor (TES) that consists of a bilayer of iridium and gold (Ir/Au). In this paper, we have studied the superconducting transition characteristics of two different bilayer structures. Type 1 is a simple stacked bilayer where a square-pattern film of iridium is covered with an identical pattern of gold. Type 2 is based on the Type 1 Ir/Au film, however, it has Au side banks. The resistance-temperature characteristics of these films are investigated by a four-wired resistance measurement method. As a result, the transition curve of Type 2 obeyed the Ginzburg–Landau (GL) theory; however, the transition curve of Type 1 was entirely different from that of Type 2. The reason there was a difference in these transition curves of the two devices is discussed in terms of the difference in the electric current distribution inside TESs. Even if we assume a uniform bilayer film and a uniform proximity effect over the entire film, the current density inside the device affects the characteristics of the transition curves.
Statistical shape model for automatic skull-stripping of brain images (2003)

Presents a statistical shape model for automatic skull stripping of MR brain images. A surface model of the brain boundary is hierarchically represented by a set of overlapping surface patches, each of which has elastic properties and a deformation range that is learned from a training set. The model's deformation is hierarchical which adds robustness to local minima. Moreover, the deformation of the model is constrained and guided by global shape statistics. The model is deformed to the brain boundary by a procedure that matches the local image structures and evaluates the similarity in the whole patch rather than on a single vertex. The experimental results show high agreement between automatic and supervised skull-stripping results.
Tenders for European cereal export refunds : a structural approach (1994)

Les restitutions à l'exportation de céréales européennes sont majoritairement attribuées par voie d'adjudication. La théorie des enchères est appliquée aux stratégies d'offre de prix d'achat de stocks d'intervention de blé tendre par les opérateurs. Ceci permet de caractériser le comportement de ces derniers, face à un tel instrument de régulation des marchés. La spécification et la méthode d'estimation des stratégies d'offre optimales sont développées sous deux hypothèses contrastées, relatives aux évaluations individuelles des céréales par ces opérateurs. Il s'agit des paradigmes de "valeurs privées" et de "valeur commune". Une hypothèse peu restrictive conduit à une forme réduite des modèles dont l'estimation est relativement simple, hormis quelques calculs additionnels nécessaires à une caractérisation complète des distributions latentes correspondant à chaque paradigme. Les résultats empiriques permettent finalement de conclure aux deux éléments suivants : d'une part l'hypothèse de valeur commune est la plus appropriée, ce qui signifie que les comportements des agents sont dictés par une référence unique sur le marché mondial, d'autre part la procédure d'adjudication utilisée par la Commission européenne se montre efficace, puisque les exportateurs ne tireraient pratiquement aucune rente lors de l'achat des stocks d'intervention.
Activation Mechanism of the Bacteroides fragilis Cysteine Peptidase, Fragipain (2016)

Enterotoxigenic Bacteroides fragilis produces a secreted metalloprotease known as B. fragilis toxin (BFT), which contributes to anaerobic sepsis, colitis, and colonic malignancy in mouse models of disease. A C11 family cysteine protease, fragipain (Fpn), directly activates BFT in the B. fragilis cell by removing the BFT prodomain. Fpn is itself a proenzyme and is autoactivated upon cleavage at an arginine residue in its activation loop. We have defined the proteolytic active site of Fpn, demonstrated that Fpn autoactivation can occur by an in trans loop cleavage mechanism, and characterized structural features of the Fpn activation loop that control peptidase activity against several substrates, including BFT. An arginine residue at the autocleavage site determines the fast activation kinetics of Fpn relative to the homologous C11 protease, PmC11, which is cleaved at lysine. Arginine to alanine substitution at the cleavage site ablated peptidase activity, as did partial truncation of the Fpn activation loop. However, complete truncation of the activation loop yielded an uncleaved, pro form of Fpn that was active as a peptidase against both Fpn and BFT substrates. Thus, Fpn can be transformed into an active peptidase in the absence of activation loop cleavage. This study provides insight into the mechanism of fragipain activation and, more generally, defines the role of the C11 activation loop in the control of peptidase activity and substrate specificity.
Time-Delay Systems with Band-Limited Feedback (2005)

Fast nonlinear devices with time-delayed feedback, developed for applications such as communications and ranging, typically include components that are ACcoupled, i.e. components that block zero frequencies. As an example of such a system, we describe a new opto-electronic device with band-limited feedback that uses a Mach-Zehnder interferometer as passive nonlinearity and a semiconductor laser as a current-to-opticalfrequency converter. Our implementation of the device produces oscillations in the frequency range of tens to hundreds of MHz. We observe periodic oscillations created through a Hopf bifurcation as well as quasiperiodic and high dimensional chaotic oscillations. Motivated by the experimental results, we investigate the steady-state solution and it’s bifurcations in time-delay systems with band-limited feedback and arbitrary nonlinearity. We show that the steady state loses stability, generically, through a Hopf bifurcation, which can be either supercritical or subcritical. As a result of this investigation, we find that band-limited feedback introduces practical advantages, such as the ability to control the characteristic time-scale of the dynamics, and that it introduces differences to Ikeda-type systems already at the level of steady-state bifurcations, e.g. bifurcations exist in which limit cycles are created with periods other than the fundamental “period-2” mode found in Ikeda-type systems.
Set-Membership Error-in-Variables Identification Through Convex Relaxation Techniques (2011)

In this technical note, the set membership error-in-variables identification problem is considered, that is the identification of linear dynamic systems when both output and input measurements are corrupted by bounded noise. A new approach for the computation of parameter uncertainty intervals is presented. First, the identification problem is formulated in terms of nonconvex optimization. Then, relaxation techniques based on linear matrix inequalities are employed to evaluate parameter bounds by means of convex optimization. The inherent structured sparsity of the original identification problems is exploited to reduce the computational complexity of the relaxed problems. Finally, convergence properties and complexity of the proposed procedure are discussed. Advantages of the presented technique with respect to previously published results are discussed and shown by means of two simulated examples.