gebhart/patrepeval huggingface dataset:
Acoustic Streaming via a Flexible PCB for Micropumping Applications (2016)

We present a microfluidic device for moving a fluid in a ring-shaped channel that utilizes boundary layer driven acoustic streaming as its driving mechanism. One wall of the channel is made of a flexible material and acts as the acoustic source. To help in the design process, a numerical study based on perturbation theory was conducted. A flexible printed circuit board is used as an actuator, which is excited magnetically using Lorentz forces to introduce a flexural travelling wave. The resulting streaming velocity is measured using particle tracking velocimetry and its dependence on the deflection amplitude is identified to verify the numerical results.
Faisabilité de l’évaluation d’une observation médicale par combinaison de multiples critères : méthode NICTALOP (2013)

Contexte : La rédaction d’observations ou de comptes-rendus médicaux est un exercice difficile mais d’importance majeure pour garantir la qualité de la prise en charge des patients. La méthode d’évaluation des observations influe probablement sur la qualité de leur rédaction. But : Étudier la faisabilité de l’utilisation d’une méthode d’évaluation à multiples critères baptisée NICTALOP pour une évaluation des performances des étudiants de deuxième cycle des études médicales lors d’un exercice de rédaction d’observation médicale. Méthodes : 28 étudiants en quatrième, cinquième ou sixième année d’études médicales ont rédigé l’introduction des observations médicales correspondant à deux situations médicales (l’une simple et l’autre complexe), avant et après une formation spécifique de quelques heures. Ces observations ont été évaluées selon cinq critères qui définissent l’acronyme NICTALOP : Nombre d’Idées-clés, Choix des Termes, verAcité des concepts, LOngueur et Position des idées. Un score global a été calculé combinant ces critères. Résultats : A l’évaluation initiale, les étudiants en fin d’études médicales obtiennent de meilleurs scores pour l’histoire simple (p = 0,02) mais il n’y a pas de différence pour l’histoire complexe (p = 0,4). Les étudiants qui assistent à l’ensemble de la formation améliorent significativement leurs scores (p = 0,01). Cette progression fait disparaître les différences de niveaux concernant l’histoire simple (p = 0,5) et crée une différence concernant l’histoire complexe, mieux restituée par les étudiants expérimentés (p = 0,05). Conclusion : La méthode NICTALOP permet une évaluation fine de la qualité des observations médicales qui met en évidence les écarts entre étudiants liés à l’expérience ou aux enseignements reçus.
Mapping of quantitative trait loci for phytic acid and phosphorus contents in seed and seedling of mungbean (<i>Vigna radiata</i> (L.) Wilczek) (2012)

Phytic acid (PA) is the storage form of phosphorus (P) in seeds and plays an important role in the nutritional quality of food crops. There is little information on the genetics of seed and seedling PA in mungbean [Vigna radiata (L.) Wilczek]. Quantitative trait loci (QTL) were identified for phytic acid P (PAP), total P (TP), and inorganic P (IP) in mungbean seeds and seedlings, and for flowering, maturity and seed weight, in an F(2) population developed from a cross between low PAP cultivated mungbean (V1725BG) and high PAP wild mungbean (AusTRCF321925). Seven QTLs were detected for P compounds in seed; two for PAP, four for IP and one for TP. Six QTLs were identified for P compounds in seedling; three for PAP, two for TP and one for IP. Only one QTL co-localized between P compounds in seed and seedling suggesting that low PAP seed and low PAP seedling must be selected for at different QTLs. Seed PAP and TP were positively correlated with days to flowering and maturity, indicating the importance of plant phenology to seed P content.
Repair of abasic sites by mammalian cell extracts (1994)

Hamster cell extracts that perform repair synthesis on covalently closed circular DNA containing pyrimidine dimers, were used to study the repair of apurinic/apyrimidinic (AP) sites and methoxyamine (MX)-modified AP sites. Plasmid molecules were heat-treated at pH 5 and incubated with MX when required. The amount of damage introduced ranged from 0.2 to 0.9 AP sites/kb. Extracts were prepared from the Chinese hamster ovary CHO-9 cell line and from its derivative, 43-3B clone which is mutated in the nucleotide excision repair (NER) ERCC1 gene. AP and MX-AP sites stimulated repair synthesis by CHO-9 cell extracts. The level of synthesis correlated with the number of lesions and was of similar magnitude to the repair stimulated by 4.3 u.v. photoproducts/kb. Repair of AP and MX-AP sites was faster than the repair of u.v. damage and was independent of ERCC1 gene product. The high level of repair replication was due to a very efficient and rapid incision of plasmids carrying AP or MX-AP sites, performed by abundant AP endonucleases present in the extract. The calculated average repair patch sizes were: 7 nucleotides per AP site; 10 nucleotides per MX-AP site; 28 nucleotides per (6-4) u.v. photoproduct or cyclobutane pyrimidine dimer. The data indicate that AP and MX-AP sites are very efficiently repaired by base-excision repair in mammalian cells and suggest that MX-AP sites may also be processed via alternative repair mechanisms.
Air Pollution and Cardiovascular Disease (2011)

Numerous epidemiological studies report consistent associations between exposure to urban air pollution and cardio-respiratory morbidity and mortality. One of the important discoveries of these epidemiological studies during the last decade was that the increased mortality associated with enhanced air pollution exposure was not due only to pulmonary diseases, but mainly to cardiovascular diseases. (Zanobetti et al. 2003, Samet et al. 2000, Dockery et al. 1993, Jerrett et al. 2005, Pope et al. 2004a, Pope et al. 2002, Simkhovich, Kleinman and Kloner 2008, Nawrot, Nemmar and Nemery 2006, Hoek et al. 2002, Katsouyanni et al. 2001, Dominici et al. 2003). The focus in the initial epidemiological research was directed towards the association between both short-term and long-term exposure to air pollution and arterial cardiovascular effects, such as myocardial infarction. These landmark studies, in the beginning of the 90's, were quickly followed by experimental studies in humans and in rodents, to unravel the underlying pathophysiological mechanisms. The number of publications in this field increased exponentially, so that by the beginning of 2011, a search through PubMed using the MeSH terms 'air pollution' and 'cardiovascular disease' retrieved almost 1300 hits. Ambient environmental air pollutants include gaseous (carbon monoxide, nitrogen oxides, sulfur dioxide, ozone) and particulate components. The particulate component, particulate matter (PM), is subdivided based on size ranges into 'thoracic particles' (PM10, with a mean aerodynamic diameter 2.5 μm and <10 μm), 'fine particles' (PM2.5, <2.5 μm), and ultra-fine particles (UFP, <0.1 μm). Although exposure to some gaseous components has been linked to cardiovascular events, the larger body of evidence points towards the deleterious effects of the particulates in air pollution. Therefore, this chapter will focus mainly on the cardiovascular morbidity induced by PM exposure. Active cigarette smoking has been established as a major independent cause of cardiovascular disease (HHS 2004). The inhaled dose of fine particles from ambient air pollution, as from secondhand cigarette smoke, is extremely small compared with that from active cigarette smoking. Accordingly, the estimated relative risks from active smoking, even at relatively light smoking levels, are substantially larger than the risks from ambient air pollution or secondhand smoke. However, the risks induced by these latter 2 types of exposure are higher than would be expected from a simple linear extrapolation based on the amount of inhaled PM from active smoking (Pope et al. 2009), and have important public health implications (Nawrot et al. 2011).
Multiscale Sensing of Bone-Implant Loosening for Multifunctional Smart Bone Implants: Using Capacitive Technologies for Precision Controllability (2022)

The world population growth and average life expectancy rise have increased the number of people suffering from non-communicable diseases, namely osteoarthritis, a disorder that causes a significant increase in the years lived with disability. Many people who suffer from osteoarthritis undergo replacement surgery. Despite the relatively high success rate, around 10% of patients require revision surgeries, mostly because existing implant technologies lack sensing devices capable of monitoring the bone-implant interface. Among the several monitoring methodologies already proposed as substitutes for traditional imaging methods, cosurface capacitive sensing systems hold the potential to monitor the bone-implant fixation states, a mandatory capability for long-term implant survival. A multifaceted study is offered here, which covers research on the following points: (1) the ability of a cosurface capacitor network to effectively monitor bone loosening in extended peri-implant regions and according to different stimulation frequencies; (2) the ability of these capacitive architectures to provide effective sensing in interfaces with hydroxyapatite-based layers; (3) the ability to control the operation of cosurface capacitive networks using extracorporeal informatic systems. In vitro tests were performed using a web-based network sensor composed of striped and interdigitated capacitive sensors. Hydroxyapatite-based layers have a minor effect on determining the fixation states; the effective operation of a sensor network-based solution communicating through a web server hosted on Raspberry Pi was shown. Previous studies highlight the inability of current bone-implant fixation monitoring methods to significantly reduce the number of revision surgeries, as well as promising results of capacitive sensing systems to monitor micro-scale and macro-scale bone-interface states. In this study, we found that extracorporeal informatic systems enable continuous patient monitoring using cosurface capacitive networks with or without hydroxyapatite-based layers. Findings presented here represent significant advancements toward the design of future multifunctional smart implants.
Realtime object extraction and tracking with an active camera using image mosaics (2004)

Moving object extraction plays a key role in applications such as object-based videoconference, surveillance, and so on. The difficulties of moving object segmentation lie in the fact that physical objects are normally not homogeneous with respect to low-level features and it's usually tough to segment them accurately and efficiently. Object segmentation based on prestored background information has proved to be effective and efficient in several applications such as videophone, video conferencing, and surveillance, etc. The previous works, however, were mainly concentrated on object segmentation with a static camera and in a stationary background. In this paper, we propose a robust and fast segmentation algorithm and a reliable tracking strategy without knowing the shape of the object in advance. The proposed system can real-time extract the foreground from the background and track the moving object with an active (pan-tilt) camera such that the moving object always stays around the center of images.
Effects of an unsteady thermal boundary condition on forced convection heat transfer (2002)

Abstract A numerical analysis based on adjoint formulation of unsteady forced convection heat transfer is proposed to generally evaluate effects of the thermal boundary condition on the heat transfer characteristics. A numerical solution of the adjoint problem enables us to predict the heat transfer characteristics, such as the total heat transfer rate or the temperature at a specific location, when the thermal boundary conditions change arbitrarily with time. Moreover, using the numerical solution of the adjoint problem, we can obtain the optimal thermal boundary conditions in both time and space to maximize the heat transfer at any arbitrary time. Numerical solutions of the adjoint problem in a lid‐driven cavity are presented to illustrate the capability of the present method. © 2002 Wiley Periodicals, Inc. Heat Trans Asian Res, 31(3): 237–247, 2002; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/htj.10032
Kinetic Analysis and Antitumor Activity of Thiosemicarbazone Benzophenone Inhibitors of cathepsin L (2012)

Breast cancer is the most common type of cancer found in female patients. Thus, there is an extensive search of new chemotherapeutic agents that delay or arrest cancer metastasis, the main cause of death in cancer patients. Cathepsin L overexpression has been found in numerous cancer cell lines, and in breast cancer. Effective inhibition of this cysteine protease may reduce tumor growth and metastasis. Two functionalized benzophenone thiosemicarbazones (Siles, R. et al., Bioorg. Med. Chem. Lett., 2006 , 16: 4405 and Kishore, G.D. et al., Bioorg. Med. Chem. Lett., 2010 , 20: 6610 ) have shown excellent in vitro inhibitory activity against human cathepsin L. Kinetic analysis and mode of inhibition of these analogs have been characterized using human cathepsin L. The ability of these inhibitors to affect the degradation of collagen by cathepsin L has been investigated. Cell invasion and migration were inhibited using MDA‐MB‐231 cells, a breast cancer cell line, that had been exposed to these synthetic compounds. (This study was supported by Oxigene, Inc.)
SOLVENT EXTRACTION OF INORGANIC IONS (SIXTH QUARTERLY PROGRESS REPORT) (1950)

Ultraviolet absorption studies on the ferric perchlorate, per chloric acid, water system at low acidity show evidence for the existence of a Fe(0H)x complex.When hydrochloric acid is added to this system, a new absorption band, attributed to the formation of a FeCCl)^complex, appears at 3400 A? The association constant for the formation of this complex has been calculated for solutions of both low and high ionic strength.It is believed that other iron chloride complexes besides Fe(Cl)++are also present in solutions of high ionic strength.D /' , Ultraviolet absorption studies have been started on the organic phase as well as conductometric measurements on the aqueous phase of the ferric' chloride system.
Design and application of α-ketothioesters as 1,2-dicarbonyl-forming reagents (2019)

The 1,2-dicarbonyl motif is vital to biomolecules, especially natural products and pharmaceuticals. Conventionally, 1,2-dicarbonyl compounds are prepared via an α-keto acyl chloride. Based on the methods used in nature, a transition-metal-free approach for the synthesis of an α-ketothioester reagent via the combination of an α-hydroxyl ketone, elemental sulfur and a benzyl halide is reported. Mechanistic studies demonstrate that the trisulfur radical anion and the α-carbon radical of the α-hydroxy ketone are involved in this transformation. The dicarbonylation of a broad range of amines and amino acids, and importantly, cross couplings with aryl borates to construct dicarbonyl-carbon bonds are realized under mild conditions by employing this stable and convenient α-ketothioester as a 1,2-dicarbonyl reagent. The dicarbonyl-containing drug indibulin and the natural product polyandrocarpamide C, which possess multiple heteroatoms and active hydrogen functional groups, can be efficiently prepared using the designed 1,2-dicarbonyl reagent.
Almost perfect epitaxial multilayers (1977)

Multilayers composed of many pairs of GaAs and Ga(As0.5P0.5) layers have been grown epitaxially on substrates whose lattice parameter matched that of the multilayer taken as a whole. The thickness of the individual layers in the multilayer was such that it was not energetically favorable for misfit dislocations to be made. Examination of thinned portions of these samples in a transmission electron microscope operating at 200 kV revealed that they were almost dislocation-free. They contained a few long dislocations that were present to accommodate part of the imperfect matching of the multilayer to its substrate. Images of these long dislocations were used to determine the planarity of interfaces between layers. It was found that the interfaces were flat to within the accuracy of measurement.
Parkinson’s disease, L-DOPA, and endogenous morphine: A revisit (2012)

Clinical observations stemming from widespread employment of restorative L-3,4-dihydroxyphenylalanine (L-DOPA) therapy for management of dyskinesia in Parkinson's Disease (PD) patients implicate a regulatory role for endogenous morphine in central nervous system dopamine neurotransmission. Reciprocally, it appears that restorative L-DOPA administration has provided us with a compelling in vivo pharmacological model for targeting peripheral sites involved in endogenous morphine expression in human subjects. The biological activities underlying endogenous morphine expression and its interaction with its major precursor dopamine strongly suggest that endogenous morphine systems are reciprocally dysregulated in PD. These critical issues are examined from historical and current perspectives within our short review.
The drugs don't work: evaluation of educational theatre to gauge and influence public opinion on antimicrobial resistance (2019)

Increased public awareness of antimicrobial resistance (AMR) is a key component of effective antimicrobial stewardship strategies. Educational theatre combined with an expert panel was used to engage the public about AMR through delivery of a play entitled 'The drugs don't work'. Audience knowledge and understanding of AMR were measured by pre- and post-play questionnaires. Performance of the play and discussion with the expert panel significantly improved audience knowledge and understanding of AMR, including antibiotic misuse and prescribing. Educational theatre provides a positive learning experience and is an innovative method of public engagement to disseminate important public health messages.
The Magneto‐Seebeck Coefficient of Bismuth Single Crystals (1974)

Abstract The magneto‐Seebeck Coefficients α 11 (B 3 ) and α 33 (B 1 ) have been measured for pure bismuth crystals between about 20 K and room temperature in magnetic fields of up to 5.5 T. The observed behaviour has been compared with a theory due to Korenblit. It appears that a phonon‐drag component of the Seebeck coefficient at very high fields persists up to well above liquid nitrogen temperature. However, some features of the results are not in accordance with theory.
The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) — China, 2020 (2020)

Background: An outbreak of 2019 novel coronavirus diseases in Wuhan, Hubei Province, China has spread quickly nationwide. Here, we report results of a descriptive, exploratory analysis of all cases diagnosed as of February 11, 2020.
Some 2,5- and 5,6-dihalonicotinic acids and their precursors. IV (1976)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSome 2,5- and 5,6-dihalonicotinic acids and their precursors. IVFrank L. Setliff and Julie E. LaneCite this: J. Chem. Eng. Data 1976, 21, 2, 246–247Publication Date (Print):April 1, 1976Publication History Published online1 May 2002Published inissue 1 April 1976https://pubs.acs.org/doi/10.1021/je60069a037https://doi.org/10.1021/je60069a037research-articleACS PublicationsRequest reuse permissionsArticle Views179Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Influence of heat and particle fluxes nonlocality on spatial distribution of plasma density in two-chamber inductively coupled plasma sources (2012)

This study presents 2D simulations of the two-chamber inductively coupled plasma source where power is supplied in the small discharge chamber and extends by electron thermal conductivity mechanism to the big diffusion chamber. Depending on pressure, two main scenarios of plasma density and its spatial distribution behavior were identified. One case is characterized by the localization of plasma in the small driver chamber where power is deposed. Another case describes when the diffusion chamber becomes the main source of plasma with maximum of the electron density. The differences in spatial distribution are caused by local or non-local behavior of electron energy transport in the discharge volume due to different characteristic scale of heat transfer with electronic conductivity.
h5py/h5py: 2.7.0 (2017)

HDF5 for Python -- The h5py package is a Pythonic interface to the HDF5 binary data format.
Serum MicroRNA Signatures Identified in a Genome-Wide Serum MicroRNA Expression Profiling Predict Survival of Non–Small-Cell Lung Cancer (2010)

The four-miRNA signature from the serum may serve as a noninvasive predictor for the overall survival of NSCLC.
Memory independence and memory interference in cognitive development. (1993)

Recent experiments have established the surprising fact that age improvements in reasoning are often dissociated from improvements in memory for determinative informational inputs. Fuzzy-trace theory explains this memory-independence effect on the grounds that reasoning operations do not directly access verbatim traces of critical background information but, rather, process gist that was retrieved and edited in parallel with the encoding of such information. This explanation also envisions 2 ways in which children's memory and reasoning might be mutually interfering: (a) memory-to-reasoning interference, a tendency to process verbatim traces of background inputs on both memory probes and reasoning problems that simultaneously improves memory performance and impairs reasoning, and (b) reasoning-to-memory interference, a tendency for reasoning activities that produce problem solutions to erase or reduce the distinctiveness of verbatim traces of background inputs. Both forms of interference were detected in studies of children's story inferences.