gebhart/patrepeval huggingface dataset:
Antimicrobial Susceptibility of Coagulase-Negative Staphylococci Isolated from Bovine Mastitis Between 2003 and 2008 in Korea (2010)

A total of 1,444 coagulase-negative staphylococci (CNS) isolates from bovine mastitic milk samples collected during 2003-2008 in Korea were identified to the species level. Of 14 species identified, S. simulans, S. haemolyticus, and S. sciuri accounted for over 60% of the isolates. All the CNS isolates were tested for susceptibility to eight antimicrobials commonly used in dairy cattle. With a few exceptions, similar resistance patterns were observed among the CNS species: penicillin and ampicillin showed the lowest activity while amikacin, cephalothin, and gentamycin were highly effective. About 39% (557/1,444) of the CNS isolates were pan-susceptible, while 12% (175/1,444) showed resistance to four or more antimicrobials tested.
A Comparison of Advanced Distillation Control Techniques for a Propylene/Propane Splitter (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA Comparison of Advanced Distillation Control Techniques for a Propylene/Propane SplitterVikram Gokhale, Scott Hurowitz, and James B. RiggsCite this: Ind. Eng. Chem. Res. 1995, 34, 12, 4413–4419Publication Date (Print):December 1, 1995Publication History Published online1 May 2002Published inissue 1 December 1995https://pubs.acs.org/doi/10.1021/ie00039a033https://doi.org/10.1021/ie00039a033research-articleACS PublicationsRequest reuse permissionsArticle Views575Altmetric-Citations27LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Induction Chemotherapy Followed by Low-Dose Involved-Field Radiotherapy for Intracranial Germ Cell Tumors (2002)

Our results support an excellent prognosis after EP and ICE regimens followed by radiotherapy. Dose and volume can be reduced to 24 Gy in 12 fractions and involve a field set-up after EP chemotherapy for the treatment of pure germinomas.
Time-Based Formulation Strategies for Colon Drug Delivery (2022)

Despite poor absorption properties, delivery to the colon of bioactive compounds administered by the oral route has become a focus of pharmaceutical research over the last few decades. In particular, the high prevalence of Inflammatory Bowel Disease has driven interest because of the need for improved pharmacological treatments, which may provide high local drug concentrations and low systemic exposure. Colonic release has also been explored to deliver orally biologics having gut stability and permeability issues. For colon delivery, various technologies have been proposed, among which time-dependent systems rely on relatively constant small intestine transit time. Drug delivery platforms exploiting this physiological feature provide a lag time programmed to cover the entire small intestine transit and control the onset of release. Functional polymer coatings or capsule plugs are mainly used for this purpose, working through different mechanisms, such as swelling, dissolution/erosion, rupturing and/or increasing permeability, all activated by aqueous fluids. In addition, enteric coating is generally required to protect time-controlled formulations during their stay in the stomach and rule out the influence of variable gastric emptying. In this review, the rationale and main delivery technologies for oral colon delivery based on the time-dependent strategy are presented and discussed.
Influence of Novel Nano-Titanium Implant Surface on Human Osteoblast Behavior and Growth (2010)

The rapid maturation of the osteoblast-like cells on FCC titanium surface suggests that this structure could play a central role during initial phases of bone healing processes.
Oxidation of hydrogen sulfide by mixed cultures of thiobacillus denitrificans and heterotrophs (1987)

Thiobacillus denitrijicans is a strictly autotrophic and facultative anaerobe first described in detail by Baalsrud and Baalsrud.' Under anaerobic conditions nitrate may be used as a terminal electron acceptor with reduction to elemental nitrogen.Thiosulfate, elemental sulfur, and sulfide may be used as energy sources with oxidation to sulfate; however, sulfide is an inhibitory substrate.Sublette and S y l v e ~t e r ~. ~ have demonstrated that T. denitrijicans may be readily cultured anaerobically in batch and continuous reactors on H2S(g) under sulfide limiting conditions.Under these conditions sulfide concentrations in the culture medium were less than IpM resulting in very low concentrations in the reactor outlet gas (less than 0.05pM).The stoichiometry of the anaerobic oxidation of H2S(g) in batch and continuous cultures was reported and stable reactor operation demonstrated at reactor loadings as high as 4-5 mmol H2S oxidized/h/g biomass.Maximum H2S loading of the biomass was estimated at 5.4-7.7 mmol H2S/h/g biomass under sulfide limiting conditions.Sublette and S y l v e ~t e r ~, ~ have proposed a process for the microbial desulfurization of natural gas based on the oxidation of H2S(g) by Thiobacillus denitrijicans.The proposed process could be greatly simplified if aseptic operation of the reactor was not required.Accordingly, we report here a study of the effects of heterotrophic contaminants on H2S(g) oxidation by T. denitrijicans.
LEVERAGING DIGITAL ROCK PHYSICS WORKFLOWS IN UNCONVENTIONAL PETROPHYSICS: A REVIEW OF OPPORTUNITIES, CHALLENGES, AND BENCHMARKING (2019)

Abstract Digital rock physics (DRP), via both direct numerical simulation and pore-network modeling, holds great promise in terms of probing such pore-scale controls on transport, particularly with multiphase flow and sensitivity analysis of time-intensive measurements such as relative permeability. However, despite advances in micro-computed tomography (microCT) and scanning electron microscopy (SEM) techniques, obtaining cost-effective representative elementary volumes (REV) at sufficient resolution that capture dual-scale porosity and surface textures remains a formidable challenge in establishing digital rock physics as a predictive toolset. Furthermore, implementers are faced with several options of numerical solvers such as finite element method, lattice Boltzmann method, and mass balance-based pore-network modeling. This paper reviews the current status of establishing an REV and upscaling techniques for DRP in tight and/or diagenetically-altered rocks, highlighting successful and unsuccessful pore-to-core data benchmarking examples by the authors and the greater literature in terms of static and dynamic properties. The review finds that performing DRP on a single image modality is not sufficient, even for many conventional rocks, and that it is crucial to interface with experimental data, be it core analysis deliverables or subpore-scale and Darcy-scale microfluidics. In unconventional rocks, the majority of work does not leverage mesoscale simulations, instead zooming in to a discrete pore-scale scenario that is often not benchmarked with SCAL data. Even when a simulation domain is benchmarked, the matching of a discrete case with a multivariable situation is non-unique. Benchmarking with dynamic or pseudo-dynamic core data such as MICP and single phase perm will greatly help reduce variables. Finally, this paper offers a technical roadmap for the robust application of unconventional DRP for the petrophysical and general subsurface community.
Berry-enriched diet in salt-sensitive hypertensive rats : metabolic fate of (poly)phenols and the role of gut microbiota (2019)

Diets rich in (poly)phenols are associated with a reduced reduction in the incidence of cardiovascular disorders. While the absorption and metabolism of (poly)phenols has been described, it is not clear how their metabolic fate is affected under pathological conditions. This study evaluated the metabolic fate of berry (poly)phenols in an in vivo model of hypertension as well as the associated microbiota response. Dahl salt-sensitive rats were fed either a low-salt diet (0.26% NaCl) or a high-salt diet (8% NaCl), with or without a berry mixture (blueberries, blackberries, raspberries, Portuguese crowberry and strawberry tree fruit) for 9 weeks. The salt-enriched diet promoted an increase in the urinary excretion of berry (poly)phenol metabolites, while the abundance of these metabolites decreased in faeces, as revealed by UPLC–MS/MS. Moreover, salt and berries modulated gut microbiota composition as demonstrated by 16S rRNA analysis. Some changes in the microbiota composition were associated with the high-salt diet and revealed an expansion of the families Proteobacteria and Erysipelotrichaceae. However, this effect was mitigated by the dietary supplementation with berries. Alterations in the metabolic fate of (poly)phenols occur in parallel with the modulation of gut microbiota in hypertensive rats. Thus, beneficial effects of (poly)phenols could be related with these interlinked modifications, between metabolites and microbiota environments.
Computer Sound Synthesis for the Electronic Musician (1998)

From the Publisher:
* Free CD-ROM with samples 
* Ideal for music technology students and professional musicians

Computer Sound Synthesis for the Electronic Musician is intended to introduce computer sound synthesis techniques and synthesis programming to students, researchers, musicians and enthusiasts in the field of music technology.

Computer sound synthesis is becoming increasingly attractive to a wide range of musicians. The sound processing power of the computer is increasing and any personal computer will soon be able to run software in real-time, capable of synthesizing sounds using every possible technique.

The art of sound synthesis is as important for the electronic musician as the art of orchestration for symphonic music composers. Those who wish to create their own virtual orchestra of electronic instruments and produce original sounds will find this book invaluable. It examines a variety of synthesis techniques and illustrates how to turn a personal computer into a powerful and flexible sound synthesizer. The book also discusses a number of ongoing developments that may play an important role in the future of electronic music making, including the use of Artificial Intelligence techniques in synthesis software and parallel computers. The accompanying CD-ROM contains examples, complementary tutorials and a number of synthesis systems for PC and Macintosh platforms, ranging from low level synthesis programming languages to graphic front-ends for instrument and sound design. These include fully working packages, demonstration versions of commercial software and experimental programs from top research centers in Europe, North America, and South America.

About The Author
Eduardo Reck Miranda is a researcher at the Sony Computer Science Laboratory in Paris. He is one of the creators of the Brazilian Computer Music Group (NUCOM) of the Brazilian Computer Science Society (SBC); he is also a member of the International Computer Music Association (ICMA), the Brazilian Electroacoustic Music Association (SBME) and the Audio Engineering Society (AES).
Production and preliminary characterization of monoclonal antibodies to Actinobacillus sp isolated from epididymitis lesions in a ram (1985)

A panel of 55 monoclonal antibodies to an Actinobacillus sp isolate (As8C strain) cultured from the epididymides of an infected ram was produced. Cell lines producing 5 of these antibodies were cloned and expanded by hybridoma tumor production in Balb/c mice. An isotype profile revealed that 1 cloned antibody belonged to the immunoglobulin (Ig) M class and the 4 remaining antibodies belonged to the IgG class. Within the IgG class, 1 clone produced IgG1, 1 clone produced IgG2a, and 2 clones produced IgG2b. Ascites fluid antibody titers from the cloned hybridomas ranged from 6,400 to 51,200, as determined by enzyme-linked immunosorbent assay. Specificity of the antibodies to target As8C antigens could be demonstrated by enzyme-linked immunosorbent assay inhibition. Ascites fluid from 2 clones contained antibodies that agglutinated As8C. Two additional clones produced antibodies capable of only partial agglutination, whereas 1 clone produced antibody that did not agglutinate As8C. The indirect fluorescent antibody test revealed that target antigens for at least 4 of the 5 monoclonal antibodies were most likely located on the bacterial cell surface. Antigens were extracted from As8C, using 5 surface active chemicals. An attempt to immunoprecipitate these antigens in agarose by reacting individual extracts with each of the antibodies was unsuccessful.
Nucleic Acid Packaging of DNA Viruses (2006)

Bacteriophages are viruses whose hosts are bacteria. Bacteriophages are the most numerous and genomically diverse form of life in the environment. Many bacteriophage genes have either (1) no detectable homology to any other bacteriophage/cellular gene or (2) homology to extremely diverged bacteriophage genes of presumably similar function. When infecting a host bacterial cell, a double-stranded DNA bacteriophage produces proteins that package progeny DNA genomes in a protein container (capsid) that protects its genome when the bacteriophage is outside of a cell. The energy requirement for DNA packaging is approximately 0.5 kcal mol−1 of packaged nucleotide pair. The capsid and accessory proteins join to form an ATP-fueled motor that drives the DNA molecule into a cavity in the capsid. The motor packages the DNA molecule via end-first motion through a portal ring also called the connector. An accessory protein/ATPase is at least the spark plug of the motor. Bacteriophage DNA packaging motors are investigated as a prototype for understanding other biological motors. Testing for feedback control of the motor is an important current objective. Investigations of both bacteriophage DNA packaging and bacteriophage capsid assembly have produced in vitro systems that are complex. One strategy for analysis of such complex systems is observation at the level of single events (single-particle analysis). Single-particle analysis has already revealed surprising cooperativity among DNA packaging events and has also revealed a comparatively strong motor capable of generating about 40 to 70 pN of force while intermittently hesitating. Bacteriophage DNA packaging systems are useful for further developing procedures for single-particle analysis of complex biochemical systems.
The Hardest Superconducting Metal Nitride (2015)

Transition-metal (TM) nitrides are a class of compounds with a wide range of properties and applications. Hard superconducting nitrides are of particular interest for electronic applications under working conditions such as coating and high stress (e.g., electromechanical systems). However, most of the known TM nitrides crystallize in the rock-salt structure, a structure that is unfavorable to resist shear strain, and they exhibit relatively low indentation hardness, typically in the range of 10-20 GPa. Here, we report high-pressure synthesis of hexagonal δ-MoN and cubic γ-MoN through an ion-exchange reaction at 3.5 GPa. The final products are in the bulk form with crystallite sizes of 50 - 80 μm. Based on indentation testing on single crystals, hexagonal δ-MoN exhibits excellent hardness of ~30 GPa, which is 30% higher than cubic γ-MoN (~23 GPa) and is so far the hardest among the known metal nitrides. The hardness enhancement in hexagonal phase is attributed to extended covalently bonded Mo-N network than that in cubic phase. The measured superconducting transition temperatures for δ-MoN and cubic γ-MoN are 13.8 and 5.5 K, respectively, in good agreement with previous measurements.
Nonlithographic Fabrication of Microfluidic Devices (2006)

A facile nonlithographic method for expedient fabrication of microfluidic devices of poly(dimethylsiloxane) is described. Positive-relief masters for the molds are directly printed on smooth substrates. For the formation of connecting channels and chambers inside the polymer components of the microfluidic devices, cavity-forming elements are adhered to the surfaces of the masters. Using this nonlithographic approach, we fabricated microfluidic devices for detection of bacterial spores on the basis of enhancement of the emission of terbium (III) ions.
The Equilibrium Behavior of the Silicon-Hydrogen-Chlorine System (1964)

The composition of the gas phase is calculated for various temperatures, pressures, and chlorine-to-hydrogen ratios for the two-phase system consisting of solid silicon in equilibrium with the gas phase. It is shown that in the range of variables most frequently used for vapor growth of silicon, the principal species under equilibrium conditions are H <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> , HCl, SiHCl <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</inf> , and SiCl <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> .
Pulmonary Function and Dysfunction in Multiple Sclerosis (1988)

Pulmonary function was studied in 25 patients with clinically definite multiple sclerosis with a range of motor impairment. Forced vital capacity (FVC), maximal voluntary ventilation (MVV), and maximal expiratory pressure (MEP) were normal in the ambulatory patients (mean greater than or equal to 80% predicted) but reduced in bedridden patients (mean, 38.5%, 31.6%, and 36.3% predicted; FCV, MVV, and MEP, respectively) and wheelchair-bound patients with upper extremity involvement (mean, 69.4%, 50.4%, and 62.6% predicted; FVC, MVV, and MEP, respectively). Forced vital capacity, MVV, and MEP correlated with Kurtzke Expanded Disability Status scores (tau = -0.72, -0.70, and -0.65) and expiratory muscle weakness occurred most frequently. These findings demonstrate that marked expiratory weakness develops in severely paraparetic patients with multiple sclerosis and the weakness increases as the upper extremities become increasingly involved.
Etude de réactions de transfert d'électron : applications à la synthèse de composés possédant une activité pharmacologique (1987)

Etude de la reaction biomimetique entre divers nitro-5 imidazoles et l'anion du nitro-2 propane ; obtention d'analogues de l'histamine. Etude du mecanisme srn1 de la reaction
The fat and the bad: Mature adipocytes, key actors in tumor progression and resistance (2017)

Growing evidence has raised the important roles of adipocytes as an active player in the tumor microenvironment. In many tumors adipocytes are in close contact with cancer cells. They secrete various factors that can mediate local and systemic effects. The adipocyte-cancer cell crosstalk leads to phenotypical and functional changes of both cell types, which can further enhance tumor progression. Moreover, obesity, which is associated with an increase in adipose mass and an alteration of adipose tissue, has been established as a risk factor for cancer incidence and cancer-related mortality. In this review, we summarize the mechanisms of the adipocyte-cancer cell crosstalk in both obese and lean conditions as well as its impact on cancer cell growth, local invasion, metastatic spread and resistance to treatments. Better characterization of cancer-associated adipocytes and the key molecular events in the adipocyte-cancer cell crosstalk will provide insights into tumor biology and suggest efficient therapeutic opportunities.
Lossless and Dissipative Distributed Systems (2002)

This paper deals with linear shift-invariant distributed systems. By this we mean systems described by constant coefficient linear partial differential equations. We define dissipativity with respect to a quadratic differential form, i.e., a quadratic functional in the system variables and their partial derivatives. The main result states the equivalence of dissipativity and the existence of a storage function or a dissipation rate. The proof of this result involves the construction of the dissipation rate. We show that this problem can be reduced to Hilbert's 17th problem on the representation of a nonnegative rational function as a sum of squares of rational functions.
Anaplastic Large Cell Lymphoma Occurring in Association With Breast Implants (2013)

Primary lymphomas of the breast are uncommon, and mostly of B-cell type. In the late 1990s, reports began to appear,primarily in the Pathology literature, of an apparently new category of breast lymphoma of T-cell type, having a particular association with silicone breast implants. This condition came to be recognized as implant-associated anaplastic large cell lymphoma.Appearing initially as individual case reports, the pathologic features were somewhat variable and the diagnosis was difficult. This review describes the pathologic and immunohistochemical features of implant-associated anaplastic large cell lymphoma of the breast drawn from a series of 103 cases. Recommendations are given for the management of removed implants, for the approach to differential diagnosis and the choice of initial immunohistochemical panels.
Fundamental Study of the Optical and Vibrational Properties of Fx-AZB@MOF systems as Functions of Dye Substitution and the Loading Amount (2022)

Controlling the switching efficiency of photoactive hybrid systems is an obligatory key prerequisite for systematically improving the design of functional materials. By modulating the degree of fluorination and the amount being embedded into porous hosts, the <i>E</i>/<i>Z</i> ratios of fluorinated azobenzenes were adjusted as both functions of substitution and the degree of loading. Octafluoroazobenzene (F8-AZB) and perfluoroazobenzene (F10-AZB) were inserted into porous DMOF-1. Especially for perfluoroazobenzene (F10-AZB), an immense stabilization of the <i>E</i> isomer was observed. In complementary molecular dynamics simulations performed at the DFTB (density functional tight binding) level, an in-depth characterization of the interactions of the different photoisomers and the host structure was carried out. On the basis of the resulting structural and energetic data, the experimentally observed increase in the amount of the <i>Z</i> conformer for F8-AZB can be explained, while the stabilization of <i>E</i>-F10-AZB can be directly related to a fundamentally different interaction motif compared to its tetra- and octafluorinated counterparts.