gebhart/patrepeval huggingface dataset:
Factors Influencing Survivorship in Vasculopathic Patients (2019)

Total knee arthroplasty (TKA) in patients with peripheral vascular disease has sparsely been studied. This study examined patient and radiographic factors that could affect reoperation free survival in these patients. We retrospectively reviewed TKA procedures performed in patients with nonpalpable pulses on physical examination between January 1, 2004, and December 31, 2013. Ninety-two cases met inclusion criteria. Preoperative ankle-brachial index (ABI), date of surgery, sex, age, body mass index (BMI), tourniquet use, American Society of Anesthesiologists (ASA) score, presence of preoperative calcifications, and follow-up data were obtained. Failure was defined as reoperation. Patients were included if they experienced a failure or had at least 2 years of follow-up. Reoperation free survival was calculated by Kaplan-Meier's analysis. Odds ratios (ORs) were calculated for patient factors; hazard ratios (HRs) were calculated by Cox's regression analysis. Ninety-two TKAs were included in the study. Mean age was 68.8 years, mean BMI was 32.15, and mean ASA score was 2.44. Tourniquet was used in 78 patients. Mean preoperative ABI was 1.016. Nine patients had calcifications on X-ray prior to surgery. Reoperation free survival was 9.378 years. Patients with a preoperative ABI of below 0.7 had shorter reoperation free survival (ABI <0.7, 6.854 years; ABI >0.7, 9.535 years; <i>p</i> = 0.015). Patients with a preoperative ABI below 0.7 had greater odds of failure and were at higher risk for earlier failure (OR = 6.5, <i>p</i> = 0.027; HR = 1.678, <i>p</i> = 0.045). When corrected for age, sex, and BMI, the HR for patients with a preoperative ABI below 0.7 worsened (HR = 1.913, <i>p</i> = 0.035) compared with those with an ABI above 0.7. The remaining patient factors produced no statistically significant differences in survivorship, odds of failure, or HRs. No patient factors were associated with increased risk of mortality. These results suggest that patients who undergo TKA with an ABI below 0.7 are at increased risk for reoperation and have shorter reoperation free survival.
Incidence of pre‐eclampsia: effect of deprivation (2022)

The incidence of PE is higher in women living in the most deprived areas in South East England and in black women (vs those of other racial groups), who also live in areas of higher deprivation. However, in screening for PE, inclusion of IMD does not improve the prediction of PE provided by race and other maternal characteristics and elements of medical history. © 2022 International Society of Ultrasound in Obstetrics and Gynecology.
Discovery of Novel Agonists and Antagonists of the Free Fatty Acid Receptor 1 (FFAR1) Using Virtual Screening (2008)

The G-protein-coupled receptor free fatty acid receptor 1 (FFAR1), previously named GPR40, is a possible novel target for the treatment of type 2 diabetes. In an attempt to identify new ligands for this receptor, we performed virtual screening (VS) based on two-dimensional (2D) similarity, three-dimensional (3D) pharmacophore searches, and docking studies by using the structure of known agonists and our model of the ligand binding site, which was validated by mutagenesis. VS of a database of 2.6 million compounds followed by extraction of structural neighbors of functionally confirmed hits resulted in identification of 15 compounds active at FFAR1 either as full agonists, partial agonists, or pure antagonists. Site-directed mutagenesis and docking studies revealed different patterns of ligand-receptor interactions and provided important information on the role of specific amino acids in binding and activation of FFAR1.
Isolation and characterization of variant benzo[a]pyrene-resistant T47D human breast-cancer cells (1996)

T47D human breast cancer cells were grown in 1 microM benzo[a]pyrene (BaP) for 3.5 months, and 2 BaP-resistant (BaPr) variant cell lines (CS and C10) were isolated. Decreased aryl hydrocarbon (Ah)-responsiveness in the CS and C1O BaPr cells was characterized by lower (80 to 900/o) induction of CYP1A1-dependent activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), lower levels of the nuclear Ah receptor complex and significantly decreased Ah receptor mRNA levels. Nuclear estrogen receptor (ER) binding and ER mRNA levels were similar in wild-type and mutant cell lines, whereas epidermal growth factor receptor mRNA levels were significantly decreased in the variant BaPr T47D cells. 17beta-Estradiol induced proliferation of both wild-type and BaPr T47D cells, and TCDD inhibited this response but did not down-regulate nuclear ER levels. The unique characteristics of the BaPr T47D variant cells will be used to further elucidate the mechanism of interaction between the ER and Ah receptor signalling pathways.
S,S-Dimethyl Dithiocarbonate: A Useful Reagent for Efficient Conversion of Aldoximes to Nitriles (2004)

Dimethyl dithiocarbonate (DMDTC) has been shown to be an efficient dehydrating agent for a range of oximes derived from aliphatic, aromatic and heteroaromatic aldehydes yielding the corresponding nitriles in high yields.
Role of colloidal interactions in oil sand tailings treatment (2005)

Abstract To provide fundamental insights into the treatment of oil sand tailings, the forces between a clay fine or silica particle and a silica wafer in aqueous solutions were measured using an atomic force microscope. A high molecular weight, partially hydrolyzed polyacrylamide (HPAM) was used as the flocculant. The effect of polymer dosage, solution pH, and addition of calcium and magnesium ions on the interaction and adhesion forces was studied. Tailings settling tests were carried out to link the measured forces with tailings treatment. The results showed that the addition of the polymer at low dosages or divalent ions at low concentrations resulted in adhesion interactions. The adhesion force increased with increasing polymer dosage or cation concentration until an optimum dosage or concentration was reached. Higher polymer dosage and ion concentration resulted in a weaker adhesion or even purely repulsive force profiles. The synergy of the polymer and divalent ions significantly enhanced the adhesion between fine solids. The measured adhesion forces correlated well with settling characteristics: the stronger the adhesion, the higher the initial settling rate. This study suggests a potential new technology for oil sand tailings treatment using the synergic effect of polymers and divalent cations. © 2005 American Institute of Chemical Engineers AIChE J, 2006
IC‐P‐093: Influence of iron genes and gender on brain iron and cognition (2009)

Brain iron increases with age and is abnormally elevated early in the disease process in several neurodegenerative disorders including Alzheimer's disease (AD). Studies have liked higher iron levels in males with younger age at onset and presence of the HFE hemochromatosis and transferrin C2 gene variants (iron genes) with AD. Examine whether cognitive performance in healthy older individuals is associated with increased brain ferritin iron and highly prevalent iron genes. Ferritin iron can be measured with specificity in vivo with MRI utilizing the Field Dependent Relaxation Rate Increase (FDRI) method. FDRI was assessed in basal ganglia, hippocampus, and white matter. 48% of the sample carried neither gene (the IRON- group) and 52% carried one and/or the other (IRON+ group). A robust gender by gene group interaction was observed. IRON+ men had significantly higher FDRI compared to the IRON- group but in secondary analyses only the caudate nucleus showed a significant FDRI increase in IRON+ compared to IRON- men (t = 2.31, p = .027). This gene effect was not observed in women. Independent of genes, memory performance was significantly associated with hippocampal iron in men but not in women. This is the first evidence that these prevalent mutations can influence brain iron levels in men. Irrespective of gene status, verbal memory is negatively associated with hippocampal iron accumulation in men. Clinical phenomena such as gender-associated risk of developing neurodegenerative diseases and age at onset may be associated with the interactions between iron genes and brain ferritin iron accumulation. Reducing brain iron accumulations in old age may be a worthwhile therapeutic target for age-related neurodegenerative diseases.
Coordinated care affects hospitalization and prognosis in amyotrophic lateral sclerosis: a cohort study (2015)

Network care was associated with fewer hospital admissions, reduced functional deterioration and later mortality in ALS. These results suggest that proactive coordination between carers in chronic and complex diseases could have a positive impact on hospitalization and the clinical course of the disease.
Transform-based image compression by noise reduction and spatial modification using boolean minimization (2004)

A method for the lossy compression of multivalued images using transform-based Boolean minimization is described. Blocks in bit-planes of an image are minimized, and the results of these minimizations are used to detect and reduce noise (sandy regions) and spatial complexity in the blocks. Specifically, the techniques of "minterm uniformalization" and "minterm quantization and thresholding" are presented as methods of discarding perceptually insignificant information from a minimized representation of an image and use data readily available from minimization without the calculation of complicated measures. Experimentally, results comparable to JPEG and better than existing binary techniques can be expected. Fast algorithms may be used, no multiplications are required, and decompression is performed without an inverse transform. Therefore, an emphasis is placed on the use of these algorithms for low-complexity or very high-speed hardware implementations for communications, for distributed and parallel sensor and computing applications, as well as for database storage.
Experimental Flight Characterization of Asymmetric and Maneuvering Projectiles from Elevated Gun Firings (2012)

Covers advancements in spacecraft and tactical and strategic missile systems, including subsystem design and application, mission design and analysis, materials and structures, developments in space sciences, space processing and manufacturing, space operations, and applications of space technologies to other fields.
Second Annual Meeting of the Neurocritical Care Society (2004)

From the *Department of Anesthesia, University of Pennsylvania, Philadelphia, PA and †Department of Anesthesiology, Harborview Medical Center, University of Washington, Seattle, WA.
FPGA High-level Synthesis versus Overlay (2017)

To promote FPGA to a wider user community and to increase design productivity, two new design methodologies, namely FPGA high-level synthesis (HLS) and FPGA overlay, are presented to use a high-level design abstraction. To make clear distinguish features of each design methodology, we make an comparison of a state-of-the-art FPGA HLS tool, Vivado HLS, and an FPGA overlay tool, ArchSyn, on two computation intensive kernels, matrix-matrix multiplication and fast Fourier transform. In the comparison, FPGA overlay shows an overwhelming superiority in computation performance, which is 8X to 39X faster than FPGA HLS. However, FPGA HLS exhibits its advantages in dynamic power consumption metric. It achieves up to 17X lower power consumption than FPGA overlay. Power- and energy-efficiency are another two essential metrics evaluating trade-offs between performance and power consumption. As demonstrated with evaluation results, FPGA overlay is averagely 3.5X better in powerefficiency for FFT kernel, and achieves up to 2 orders of magnitude better energy-efficiency than FPGA HLS.
Anti-jamming GPS receivers based on bilinear signal distributions (2002)

In this paper, we propose a nonstationary jammer suppression technique for GPS receivers. This technique is based on using the time-frequency distributions (TFDs) to define the jammer time-frequency (t-f) signature. A mask can be constructed and applied such that the masked t-f region captures the jammer energy, but leaves out most of the GPS signals. The jammer signals are synthesized from the masked TFDs and removed from the received signal by orthogonal projection. A method for determining an appropriate mask is discussed. We extend the proposed jammer excision method to multi-antenna GPS receivers.
Design of a CMOS Bandgap Reference with Low Temperature Coefficient and High Power Supply Rejection Performance (2011)

A high precision temperature compensated CMOS bandgap reference is presented. The proposed circuit employs current-mode architecture that improves the temperature stability of the output reference voltage as well as the power supply rejection when compared to the conventional voltage-mode bandgap referenc. Using only first order compensation the new architecture can generate an output reference voltage of 550mV with a peak-to-peak variation of 400V over a wide temperature range from -25 o C to +100 o C which corresponds to a temperature coefficient of 5.8ppm/oC. The output reference voltage exhibits a variation of 2.4mV for supply voltage ranging from 1.6V to 2.0V at typical process corner. A differential cascaded three-stage operational amplifier is included in the bandgap circuit to improve the power supply rejection of the BGR. Simulation result shows that the power supply rejection ratio of the proposed circuit is 79dB from DC up to 1kHz of frequency. The proposed bandgap reference is implemented using UMC 0.18m CMOS process and it occupies an active layout area of 0.14mm 2 .
Preparation of Intumescent Fire Protective Coating for Fire Rated Timber Door (2019)

Intumescent flame-retardant coating (IFRC) provides a protective barrier to heat and mass transfer for the most efficient utilization of a wide variety of passive fire protection systems at the recent development. This article highlights the fire-resistance, physical, chemical, mechanical, and thermal properties of the IFRC using a Bunsen burner, furnace, Scanning Electron Microscope, freeze-thaw stability test, Instron Micro Tester, and thermogravimetric analysis (TGA) test. The five IFRC formulations were mixed with vermiculite and perlite for the fabrication of fire-resistant timber door prototypes in this research project. Additionally, the best fire-resistance performance of the fire-rated door prototype was selected and compared with a commercial prototype under the fire endurance test. An inventive fire-rated door prototype (P2), with a low density of 636.45 kg/m3, showed an outstanding fire-resistance rating performance, resulting in temperature reduction by up to 54.9 °C, as compared with that of the commercial prototype. Significantly, a novel fire-rated timber door prototype with the addition of formulating intumescent coating has proven to be efficient in preventing fires and maintaining its integrity by surviving a fire resistance period of 2 h.
Use of sagittal images for localization of the subthalamic nucleus (2005)

Direct observation of the subthalamic nucleus (STN) is not always possible, and physicians at many centers rely on indirect methods that relate the position of the STN to more easily recognized structures such as the red nucleus (RN). In this paper the authors describe an indirect method of viewing the STN based on the anatomy depicted on sagittal magnetic resonance (MR) images. A review of sagittal slices appearing in standard stereotactic atlases showed that the STN lies within the angle formed by the descending internal capsule (IC) and the substantia nigra (SN). The authors' technique consists of marking the location of the STN in this nigrocapsular angle on each sagittal MR image between the RN and the lateral border of the brainstem, and transferring these points to axial MR images to build a locus of points used to describe the STN. A point is chosen in the center of this locus as the stereotactic target. Two hundred eighty-two sagittal images obtained from 71 MR imaging studies performed in 29 patients by using a fast-spin echo inversion-recovery technique were examined for the presence of the STN, the SN, and the IC. The descending IC could be detected in 97% of the slices, the SN in 95% of the slices, and the STN in 73% of the slices. This indirect method involving sagittal anatomy can be used to refine localization of the STN.
Detection of Human Intestinal Catalase-Negative, Gram-Positive Cocci by rRNA-Targeted Reverse Transcription-PCR (2010)

An analytical system based on rRNA-targeted reverse transcription-quantitative PCR (RT-qPCR) for enumeration of catalase-negative, Gram-positive cocci was established. Subgroup- or species-specific primer sets targeting 16S or 23S rRNA from Enterococcus, Streptococcus, and Lactococcus were newly developed. The RT-qPCR method using these primers together with the previously reported primer sets specific for the Enterococcus genus, the Streptococcus genus, and several Streptococcus species was found to be able to quantify the target populations with detection limits of 10(3) to 10(4) cells per gram feces, which was more than 100 times as sensitive as the qPCR method (10(6) to 10(8) cells per gram feces). The RT-qPCR analysis of fecal samples from 24 healthy adult volunteers using the genus-specific primer sets revealed that Enterococcus and Streptococcus were present as intestinal commensals at population levels of log(10) 6.2 +/- 1.4 and 7.5 +/- 0.9 per gram feces (mean +/- standard deviation [SD]), respectively. Detailed investigation using species- or subgroup-specific primer sets revealed that the volunteers harbored unique Enterococcus species, including the E. avium subgroup, the E. faecium subgroup, E. faecalis, the E. casseliflavus subgroup, and E. caccae, while the dominant human intestinal Streptococcus species was found to be S. salivarius. Various Lactococcus species, such as L. lactis subsp. lactis or L. lactis subsp. cremoris, L. garvieae, L. piscium, and L. plantarum, were also detected but at a lower population level (log(10) 4.6 +/- 1.2 per gram feces) and prevalence (33%). These results suggest that the RT-qPCR method enables the accurate and sensitive enumeration of human intestinal subdominant but still important populations, such as Gram-positive cocci.
ChemInform Abstract: A Practical Synthetic Approach to Chiral (α‐Chloroalkyl)boronic Esters via Iridium‐Catalyzed Chemoselective Hydrogenation of Chloro‐Substituted Alkenyl Boronates. (2014)

Abstract The use of a chiral iridium P,N‐complex as catalyst allows the synthesis of (α‐chloroalkyl)boronic esters with up to 94% ee accompanied by small amounts of dechlorination products.
A new kinkajou from México and a new hooded skunk from Central America. American Museum novitates ; no. 1830 (1957)

In a collection of mammals from northwestern Chiapas, Mexico, re- cently made by students of Walla Walla College under the supervision of Dr. Ernest S. Booth, there is a specimen of an unusually small kinkajou.The small size and long, thick, soft pelage of this specimen seem to warrant recognition by name of a geographical form inhabiting the highlands of northwestern Chiapas.A review of the Central American hooded skunks in the American Museum of Natural History collection shows that the specimens listed by J. A. Allen, 1908Allen, , 1910, from Nicaragua as Mephitis macroufa vittata differ sufficiently in cranial characters from named forms to be recognized as a distinct subspecies.At the time, Allen apparently based his diagnosis on measurements alone, without actually seeing typical specimens of.M. mn.vittata from southern Oaxaca.This new hooded skunk and the new kinkajou mentioned above are described below.Potos flavus boothi, new subspecies CHIAPAS
Automatic Calibration of Systematic Errors in Fast Pulse Measurements (1985)

In calibrating a precision time-interval measuring instrument such as a counter, one needs two signals separated by a known time interval at the trigger level. The waveforms of these sources should imitate as much as possible the signals to be measured in amplitude, slope, transition time etc. This paper describes a calibrator which splits a given input waveform linearly and passively into two signals which are either identical or mirrored about a given trigger level. These are measured by the counter either directly or swapped via rf relays. Through an algorithm of measurements (via HPIB) and computation, counter systematic errors can be extracted for any particular waveform type. Accuracy of the calibrator itself is better than 10 Ps, traceable to the NBS, and for the counter, better than 100 PS after calibration.
Interactive 3D teleconferencing with user-adaptive views (2004)

We present a system and techniques for synthesizing views for three dimensional video teleconferencing. Instead of performing complex 3D scene acquisition, we decided to trade storage/hardware for computation, i.e., using more cameras. While it is expensive to directly capture a scene from all possible viewpoints, we observed that the participants' viewpoints usually remain at a constant height (eye level) during video teleconferencing. Therefore we can restrict the possible viewpoint to be within a virtual plane without sacrificing much of the realism. Doing so signicantly reduces the number of cameras required. We demonstrate a realtime system that uses a linear array of cameras to perform Light-Field style rendering. The simplicity and robustness of light fielding rendering, combined with the natural restrictions of limited view volume in video teleconferencing, allow us to synthesize photo-realistic views persuser request at interactive rate.
Osmose inverse et ultrafiltration, Considérations théoriques (1974)

1 Généralités 1.1 Définitions 1.2 Osmose inverse 1.3 Ultrafiltration 1.4 Comparaison avec la filtration 1.5 Comparaison entre osmose inverse et ultrafiltration 2 Pression osmotique 2.1 Cas général. Loi de Van't Hoff 2.2 Pression osmotique des électrolytes 2.3 Pression o
<title>Ferroelectric materials for microwave and millimeter wave applications</title> (1995)

Ferroelectric materials are nonlinear dielectrics, having a dielectric constant which is a function of the electric field. The nonlinear behavior of these materials makes them candidates for the realization of advanced high frequency devices which can operate up to the millimeter range. Ferroelectrics have been successfully employed in many optical devices, but their application at high frequency has been limited, mostly due to the large bias voltage required to significantly change the electrical properties of the bulk material. However, today there are several new techniques available to produce ferroelectric thin films and thin ceramics which only require low or medium bias voltage. These processes open the way for development of a new family of devices which are fully compatible with conventional analog and digital electronic circuits. Use of tunable dielectric material finds applications in many new devices including tunable phase shifters, tunable filters, and tunable beam scan antennas. High quality thin films and thin ceramics of PbTiO<SUB>3</SUB> (PTO), BaTiO<SUB>3</SUB> (BTO), Ba<SUB>x</SUB>Sr<SUB>1-x</SUB>TiO<SUB>3</SUB> (BST), and Pb<SUB>x</SUB>Ca<SUB>1-x</SUB>TiO<SUB>3</SUB> (PCT) have been produced and characterized. A 2.5 GHz tunable phase shifter, realized using BTO in microstrip configuration, is proposed and tested.
An AVO analysis project (2001)

We present an AVO data set consisting of raw prestack seismic data, petrophysical information and well-logs. These data are the focus of an AVO workshop sponsored by Mobil. SEP’s AVO project goals include: true-amplitude preprocessing including multiple suppression, AVO analysis and impedance inversion, and developing lithologic/hydrocarbon indicators based on rock physics properties and seismic attributes. We discuss preliminary results in model building, synthetic seismogram generation and preprocessing, and briefly outline our planned research.