gebhart/patrepeval huggingface dataset:
ARE GRADUATE PROGRAM COMPLETERS READY FOR SCHOLARLY TASKS (2016)

The publish or perish mantra among faculty in academia has received a lot of attention and research compared to doctoral students about to enter academia. Objective: This article addresses the question of doctoral students’ readiness for scholarly tasks. Scholarly tasks include publication and presentation of articles at conferences. Method: Data for this study was collected from 388 doctoral program completers from 2012 to 2014 at a research university. A productivity score was generated for each participant as well as personal and academic factors and various analysis were conducted to determine variables that explained a significant portion of the variance in the productivity of the doctoral program completers. Results: The results showed that International students were significantly different from their US citizen counterparts in terms of their productivity. Secondly, scholarly productivity was significantly different by a doctoral student’s major, with students majoring in Chemistry having the highest mean productivity scores followed by doctoral students in Mechanical Engineering. Conclusion: Even though majority of the doctoral program completers did not have an internship during their graduate education, those who did, had significantly higher productivity score than those who did not. In the final Model of the hierarchical regression, four out of twelve variables helped to explain the variance in the doctoral students’ productivity. Application: A Significant variable in preparing for the workforce is having an Internship. The results and implications for future research and practice were discussed.
The prognostic impact of bone marrow involvement in patients with diffuse large cell lymphoma varies according to the degree of infiltration and presence of discordant marrow involvement (2006)

Minimal BMI, seen in the majority of patients with DLCL with marrow infiltration, appears not to influence the PFS & OS. However, an increasing degree of marrow involvement is associated with an increasing component of large cells and a poorer prognosis in DLCL patients, independent of other risk factors.
Diversity of facultatively anaerobic microscopic mycelial fungi in soils (2008)

The numbers of microscopic fungi isolated from soil samples after anaerobic incubation varied from tens to several hundreds of CFU per one gram of soil; a total of 30 species was found. This group is composed primarily of mitotic fungi of the ascomycete affinity belonging to the orders Hypocreales (Fusarium solani, F. oxysporum, Fusarium sp., Clonostachys grammicospora, C. rosea. Acremonium sp., Gliocladium penicilloides, Trichoderma aureoviride, T. harzianum, T. polysporum, T. viride. T. koningii, Lecanicillum lecanii, and Tolypocladium inflatum) and Eurotiales (Aspergillus terreus, A. niger, and Paecilomyces lilacimus), as well as to the phylum Zygomycota, to the order Mucorales (Actinomucor elegans, Absidia glauca, Mucor circinelloides, M. hiemalis, M. racemosus, Mucor sp., Rhizopus oryzae, Zygorrhynchus moelleri, Z. heterogamus, and Umbelopsis isabellina) and the order Mortierellales (Mortierella sp.). As much as 10-30% of the total amount of fungal mycelium remains viable for a long time (one month) under anaerobic conditions.
X-ray diffraction analysis and magnetic behavior of amorphous Fe15Co17Ni58B10 nanowires obtained by electrochemical deposition (2007)

Fe 15 Co 17 Ni 58 B 10 nanowire arrays have been deposited in alumina templates by electrochemical deposition. For comparison, the same alloy was used to deposit films on CuBe substrate. The change in boron concentration from 3% to 10% in the electrolyte promoted the amorphous phase in the films on the CuBe substrate and a partial amorphous phase in the nanowires. Thermal treatment of the deposited films and nanowire arrays at 600°C promoted recrystallization. Magnetic hysteresis loops for 100 and 200nm nanowire arrays are “wasp waisted.” There is no evidence of a sharp reversal for the out-of-plane or in-plane hysteresis loops, just a smooth curve indicating a coherent rotation during the magnetization reversal. Annealing the 200nm nanowire array at 600°C for 1h gives rise to a mixed hysteresis loop, which can be attributed to competing domain configurations. An alternative explanation for this behavior is that there might be a phase separation between Fe, Ni, and Co in the nanowire environment due to the short range ordering of the alloy.
Validation of screening questionnaires for evaluation of knee osteoarthritis prevalence in the general population of Singapore (2017)

Our study adapted and validated questionnaires to the local context to screen for symptomatic KOA. We estimated the prevalence of symptomatic KOA in Singapore utilizing the better-performing algorithms.
Toxicity study of dibutyl phthalate ofRubia cordifoliafruits:in vivoandin silicoanalysis (2015)

Natural toxins from plant sources with wide ranges of biological activities reflect the upswing of drug design in the pharmaceutical industry. Rubia cordifolia L. is one of the most important red dye yielding plants. Most of the former researches have focused on the bioactive compounds from the roots of R. cordifolia, while no attention was paid towards the fruits. For the first time, here we report the presence of dibutyl phthalate in the fruits of R. cordifolia. Structural characterization was carried out using Ultraviolet-Visible spectrophotometer (UV-Vis), Fourier transform infrared (FTIR), gas chromatography-mass spectrophotometer (GC-MS), Nuclear magnetic resonance (NMR). Acute toxicity of the crude ethanolic extracts of the R. cordifolia fruits was examined in Swiss albino mice. No mortality was observed in all treated mice with 100, 500, 1000 mg/kg body weight of crude extract of R. cordifolia fruit and it indicates that the LD50 value is higher than 1000 mg/kg body weight. This study exhibited a significant change in the body weight. Alanine transaminase (ALT), total protein, triglycerides, glucose, and also the histopathological analysis of liver for all treated mice showed difference from the control group. The dibutyl phthalate was further evaluated for the toxicity study through in silico analysis. Together, the results highlighted that the toxic potential of R. cordifolia fruits extracts and also the toxicity profile of the fruit should be essential for the future studies dealing with the long term effect in animals. © 2015 Wiley Periodicals, Inc. Environ Toxicol 31: 1059-1067, 2016.
Dynamic measurement-aware routing in practice (2011)

Traffic monitoring is a critical network operation for the purpose of traffic accounting, debugging or troubleshooting, forensics, and traffic engineering. Existing techniques for traffic monitoring, however, tend to be suboptimal due to poor choice of monitor location or constantly evolving monitoring objectives and traffic characteristics. One way to counteract these limitations is to use routing as a degree of freedom to enhance monitoring efficacy, which we refer to as measurement-aware routing. Traffic sub-populations can be routed (rerouted) on the fly to optimally leverage existing monitoring infrastructures. Implementing dynamic measurement-aware routing (DMR) in practice is riddled with challenges. Three major challenges are how to dynamically assess the importance of traffic flows; how to aggregate flows (and hence take a common action for them) in order to conserve routing table entries; and how to achieve traffic routing/rerouting in a manner that is least disruptive to normal network performance while maximizing the measurement utility. This article takes a closer look at these challenges and discusses how they manifest for different types of networks. Through an OpenFlow prototype, we show how DMR can be applied in enterprise networks. Using global iceberg detection and capture as a driving application, we demonstrate how our solutions successfully route suspected iceberg flows to a DPI box for further processing, while preserving balanced load distribution in the overall network.
Aspectos clínicos, imunológicos e terapêuticos da leishmaniose cutânea em idosos (2018)

Submitted by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2019-05-17T12:06:24Z No. of bitstreams: 1 Dissertacao_ICS_Alexsandro Souza do Lago.pdf: 2807407 bytes, checksum: 35e1b054470e9e92d4220e87e39fa7ca (MD5)
CrAg lateral flow assay for cryptococcosis (2012)

The CrAg LFA is recommended for use with serum, plasma or CSF for diagnosis of cryptococcal meningitis or non-meningeal cryptococcal disease in symptomatic patients. There is a need for further evaluation of LFA for screening of asymptomatic patients. However, the LFA is emerging as a valuable tool for screening of serum or plasma in ART-naive adults with CD4 counts less than 100 cells/mm(3) in geographic regions with a high prevalence of cryptococcal antigenemia. CrAg screening has the potential to identify patients with asymptomatic cryptococcal infection who should receive preemptive antifungal therapy.
Rapid Gas Chromatographic Technique for Quantifying 2‐Acetyl‐1‐Pyrroline and Hexanal in Rice (Oryza sativa, L.) (2000)

ABSTRACT The aroma of rice plays a role in its consumer acceptability. The popcorn‐like smell of aromatic rice stemming primarily from its 2‐ acetyl‐1‐pyrroline (2‐AP) content is considered desirable by many consumers. Conversely, hexanal has been correlated with off odors in rice that develop from lipid oxidation. A rapid method for 2‐AP and hexanal quantification suitable for use in breeding programs, large‐scale research efforts, and quality assurance programs is needed. While developing such a method, sample preparation (degree of milling, particle size), solvent extraction time and temperature, and gas chromatographic parameters were studied. Particle size had no influence on 2‐AP or hexanal recovered. One extraction solubilized ≈80% of the 2‐AP and 56% of the hexanal present in milled rice. The optimum extraction method was assessed to require 0.3 g of ground brown or milled rice in methylene chloride held at 85°C for 2.5 hr. The complete gas chromatographic run requires ≈25 min, and 50 samples can be analyzed per day. The optimized method's linear response ( R 2 = 0.99) and reproducibility was demonstrated. The stability of 2‐AP and hexanal in frozen milled rice and in refrigerated methylene chloride extracts was excellent for at least six months. Milled and unmilled commercial and breeders' aromatic rice samples contained 10–1,104 ng/g of 2‐AP and 148–2,541 ng/g of hexanal. Genotype had the greatest effect on the 2‐AP and hexanal content of two lines grown over four years and in four states.
Effects of the Angiotensin Receptor Blocker Candesartan on Arterial Stiffness and Markers of Extracellular Matrix Metabolism in Patients with Essential Hypertension (2006)

Laboratory studies have shown that angiotensin receptor blockers (ARBs) can affect extracellular matrix (ECM) metabolism and thereby have a beneficial effect on vascular remodeling. The aim of this study was to examine the clinical effects of the ARB candesartan cilexetil on serum markers of synthesis and degradation of ECM, as well as their relation to changes in arterial stiffness in hypertensive patients. Twenty-three patients with essential hypertension were recruited for this study. Markers related to ECM synthesis and degradation (procollagen type 1 propeptide [PIP], procollagen type III propeptide [PIIIP], matrix metalloproteinase-3 [MMP-3, stromelysin-1], tissue inhibitor of matrix metalloproteinases [TIMP-1], and hyaluronic acid [HA]) were examined both before and after one year of treatment with candesartan. Pulse-wave velocity [PWV] and ankle-brachial pressure index [ABI] were measured two months (i.e., after achieving blood pressure reduction) and one year after the initiation of therapy. PWV values after one year of treatment with ARB were significantly decreased compared to previous values, whereas ABI values were unchanged. Treatment with ARB was also associated with a significant decrease in serum PIIIP values and an increase in serum stromelysin-1, whereas changes in PIP, TIMP-1, and HA did not achieve statistical significance. A significant relationship was found between the changes in PWV and the changes in stromelysin-1 levels after correction for blood pressure and heart rate (p = 0.02). These results suggest that the treatment for just one year with ARB results in significant changes in markers of ECM metabolism as well as PWV. These effects on ECM metabolism could have a beneficial effect in decreasing vascular pathology in patients with essential hypertension.
Millimeter-Wave High-Gain PRGW Antenna Using a Fabry-Perot Cavity (2020)

This paper presents the design and simulation of a high-gain Antenna by using a Fabry-Perot cavity (FPC) in millimeter-wave (MMW) applications. The FPC antenna is formed by locating a frequency selective surfaces (FSS) above a slot antenna that operates at 28 GHz and fed by a printed ridge-gap waveguide (PRGW). Moreover, the bandwidth of the proposed slot antenna is enhanced using a novel design of the semi-cross slot. The simulation results show the optimized antenna design can cover impedance bandwidth from 27.77 GHz to 28.42 GHz with a high realized gain of about 20.45 dBi at 28 GHz.
Spiking Patterns and Their Functional Implications in the Antennal Lobe of the Tobacco Hornworm Manduca sexta (2011)

Bursting as well as tonic firing patterns have been described in various sensory systems. In the olfactory system, spontaneous bursts have been observed in neurons distributed across several synaptic levels, from the periphery, to the olfactory bulb (OB) and to the olfactory cortex. Several in vitro studies indicate that spontaneous firing patterns may be viewed as "fingerprints" of different types of neurons that exhibit distinct functions in the OB. It is still not known, however, if and how neuronal burstiness is correlated with the coding of natural olfactory stimuli. We thus conducted an in vivo study to probe this question in the OB equivalent structure of insects, the antennal lobe (AL) of the tobacco hornworm Manduca sexta. We found that in the moth's AL, both projection (output) neurons (PNs) and local interneurons (LNs) are spontaneously active, but PNs tend to produce spike bursts while LNs fire more regularly. In addition, we found that the burstiness of PNs is correlated with the strength of their responses to odor stimulation--the more bursting the stronger their responses to odors. Moreover, the burstiness of PNs was also positively correlated with the spontaneous firing rate of these neurons, and pharmacological reduction of bursting resulted in a decrease of the neurons' responsiveness. These results suggest that neuronal burstiness reflects a physiological state of these neurons that is directly linked to their response characteristics.
Microbiota‐derived tryptophan indoles increase after gastric bypass surgery and reduce intestinal permeability in vitro and in vivo (2017)

The novel findings are that obese subjects have lower levels of IPA, a solely bacterially derived tryptophan derivative, and IPA improved intestinal barrier function in vitro and DIO mice. Reduced plasma IPA levels and reversal by surgery may be a consequence of intestinal indole-producing microbiota but underlying mechanisms warrant further investigation.
Partial oxidation power plant with reheating and method thereof (2023)

A system and method for generating power having an air compression/partial oxidation system, a turbine, and a primary combustion system. The air compression/partial oxidation system receives a first air stream and a fuel stream and produces a first partially oxidized fuel stream and a first compressed air stream therefrom. The turbine expands the first partially oxidized fuel stream while being cooled by the first compressed air stream to produce a heated air stream. The heated air stream is injected into the expanding first partially oxidized fuel stream, thereby reheating it in the turbine. A second partially oxidized fuel stream is emitted from the turbine. The primary combustion system receives said second partially oxidized fuel stream and a second air stream, combusts said second partially oxidized fuel stream, and produces rotating shaft power and an emission stream therefrom.
New interrogation technique for multiplexing LPG-fiber loop mirrors based displacement sensors using an OTDR (2011)

A novel interrogation technique for multiplexing LPG-fiber loop mirrors has been proposed and experimentally demonstrated. Each displacement sensor is formed by a fiber loop mirror combined with a long period grating. This high reflectivity variable mirror is suitable to be interrogated by an OTDR and to be multiplexed in a crosstalk free setup with temperature independence.
Endoscopic Resection of Skull Base Teratoma in Klippel-Feil Syndrome through Use of Combined Ultrasonic and Bipolar Diathermy Platforms (2017)

Klippel-Feil syndrome (KFS) is associated with numerous craniofacial abnormalities but rarely with skull base tumor formation. We report an unusual and dramatic case of a symptomatic, mature skull base teratoma in an adult patient with KFS, with extension through the basisphenoid to obstruct the nasopharynx. This benign lesion was associated with midline palatal and cerebral defects, most notably pituitary and vertebrobasilar arteriolar duplications. A multidisciplinary workup and a complete endoscopic, transnasal surgical approach between otolaryngology and neurosurgery were undertaken. Out of concern for vascular control of the fibrofatty dense tumor stalk at the skull base and need for complete teratoma resection, we successfully employed a tissue resection tool with combined ultrasonic and bipolar diathermy to the tumor pedicle at the sphenoid/clivus junction. No CSF leak or major hemorrhage was noted using this endonasal approach, and no concerning postoperative sequelae were encountered. The patient continues to do well now 3 years after tumor extirpation, with resolution of all preoperative symptoms and absence of teratoma recurrence. KFS, teratoma biology, endocrine gland duplication, and the complex considerations required for successfully addressing this type of advanced skull base pathology are all reviewed herein.
Effects of Chemical Modification of Ursodeoxycholic Acid on TGR5 Activation (2011)

The aim of this study is to examine the ability of the bile acid analogues obtained by chemical modification of ursodeoxycholic acid (UDCA) for TGR5 activation. Eleven UDCA analogues including 3- or 7-methylated UDCAs and amino acid conjugates were investigated as to their ability to activate TGR5 by means of the luciferase assay. It was noteworthy that 7α-methylated UDCA, namely 3α,7β-dihydroxy-7α-methyl-5β-cholanoic acid, had a significantly high affinity for and ability to activate TGR5 as compared to UDCA. Additionally, FXR activation ability of 7α-methylated UDCA was low relative to that of UDCA. However, other modification of UDCA, such as the introduction of methyl group at its C-3 position and oxidation or epimerization of hydroxyl group in the C-3 position, could not elicit such remarkable effect. The present findings would provide a useful strategy for the development of TGR5-selective agonist.
Hypopituitarism (2022)

Abstract Hypopituitarism is the consequence of diseases or interventions resulting in deficiency of pituitary hormones. Pituitary hormone replacement is one of the most frequent clinical interventions in pituitary disease, yet is rarely been the subject of rigorous scientific evaluation. With the exception of growth hormone, anterior pituitary hormones are replaced with target hormones (sex steroids, cortisol, and thyroxine), in preference to pituitary trophic hormones, as the former have longer half-lives allowing for oral administration. The precise reason for increased morbidity and mortality associated with hypopituitarism is unclear, but underlines the importance of replacing hormones close to physiological patterns. In an era of ‘evidence-based’ medicine, recommendations are frequently based on clinical experience, consensus guidelines, and retrospective reviews rather than on randomized trials. Within these limitations, this chapter will attempt to give a balanced view on current best practice for replacement therapy in adrenocorticotropic hormone (ACTH), thyroid-stimulating hormone (TSH), and gonadotrophin deficiency.
New kinetic method for determination of ultramicro quantities of organic substances. Determination of amino acids (glycine, DL-serine, DL-phenylalanine, DL-glutamic acid, and L-arginine (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew kinetic method for determination of ultramicro quantities of organic substances. Determination of amino acids (glycine, DL-serine, DL-phenylalanine, DL-glutamic acid, and L-arginineR. C. Gueldner, F. Y. Hutto, A. C. Thompson, and P. A. HedinCite this: Anal. Chem. 1973, 45, 2, 390–393Publication Date (Print):February 1, 1973Publication History Published online1 May 2002Published inissue 1 February 1973https://pubs.acs.org/doi/10.1021/ac60324a043https://doi.org/10.1021/ac60324a043research-articleACS PublicationsRequest reuse permissionsArticle Views57Altmetric-Citations4LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
RECOIL EFFECTS OF COBALT-58 RESULTING FROM ($gamma$,n) REACTION IN COBALT COMPLEXES (1963)

The recoil effects of Co/sup 58/ resulting from Co/sup 59/ ( gamma ,n) Co/sup 58/ reaction, were studied in several cobalt chelates. The pattern of thermal annealing in ( gamma ,n) reactions was found to be very similar to that obtained for (n, gamma ) reactions, despite the very large difference in recoil energies. The experimental data were examined in the light of existing models and concepts, and a model is proposed for stabilization of the recoil atom in the form of metastable species, which possess well-defined configurational and/or electronic defects. (auth)
Unilateral Post-LASIK Ectasia and Contralateral Spontaneous Ectasia (2016)

LASIK accelerates occurrence of ectasia in ectasia-susceptible and biomechanically fragile eyes.