gebhart/patrepeval huggingface dataset:
Pre-implant right ventricular function might be an important predictor of the response to cardiac resynchronization therapy (2011)

Pre-implant decreased RV systolic function might be an important way to predict a poor response to CRT implicating that other treatments should be considered. Furthermore we found that 3D- echocardiography and Tissue Doppler Imaging were feasible to detect short-term changes in LV function.
ENSO Impact on landslide generation in northwestern Argentina (2000)

Climatic changes are of major importance in landslide generation in the Argentine Andes. Increased humidity as a potential influential factor was inferred from the temporal clustering of landslide deposits during a period of significantly wetter climate, 30,000 years ago. A change in seasonality was tested by comparing past (inferred from annual-layered lake deposits, 30,000 years old) and modern (present-day observations) precipitation changes. Quantitative analysis of cross recurrence plots were developed to compare the influence of the El Nino/Southern Oscillation (ENSO) on present and past rainfall variations. This analysis has shown the stronger influence of NE trades in the location of landslide deposits in the intra-andean basin and valleys, what caused a higher contrast between summer and winter rainfall and an increasing of precipitation in La Nina years. This is believed to reduce thresholds for landslide generation in the arid to semiarid intra-andean basins and valleys.
Gastrin stabilises β-catenin protein in mouse colorectal cancer cells (2005)

As gastrin may play a role in the pathophysiology of gastrointestinal (GI) malignancies, the elucidation of the mechanisms governing gastrin-induced proliferation has recently gained considerable interest. Several studies have reported that a large percentage of colorectal tumours overexpress or stabilise the beta-catenin oncoprotein. We thus sought to determine whether gastrin might regulate beta-catenin expression in colorectal tumour cells. Amidated gastrin-17 (G-17), one of the major circulating forms of gastrin, not only enhanced beta-catenin protein expression, but also one of its target genes, cyclin D1. Furthermore, activation of beta-catenin-dependent transcription by gastrin was confirmed by an increase in LEF-1 reporter activity, as well as enhanced cyclin D1 promoter activity. Finally, G-17 prolonged the tau(1/2) of beta-catenin protein, demonstrating that gastrin appears to exert its mitogenic effects on colorectal tumour cells, at least in part, by stabilising beta-catenin.
Holding your peace: Dror Moreh's 'The gatekeepers' (2014)

The conflict between Israel and palestine continues to rage, and over the years both sides have committed questionable acts in the name of both land and lord. Jasmine Crittenden explores the controversial documentary that exposes the Israeli side of the dispute over the holy land.
A 2 - 18 GHz Travelling Wave Lossless Two-Port Combiner (2005)

An extension of traveling wave amplifiers is applied to a lossless 2 - 18 GHz two-port combiner, realized in hybrid microstrip technology. Its amplitude weighting capability allows its use in vector phase shifters for phased array applications ; it enables also to realize a lossless n-port combiner by cascading several identical modules.
Personal full electric vehicle PICAV: Non linear dynamic model and simulation (Article) (2015)

Request of sustainable personalized transport is growing in different areas of service robotics, for aid to mobility of elderly and motion disabled people, for freight delivery in urban environment, for passengers transport in restricted zones as airports and greens because of the small dimensions, tiny footprint, on-board intelligence, friendly human car interface and zero environmental impact. The paper studies the feasibility of an electric vehicle with four non steering wheels considering as driving principle the skid steering that has been mainly used for tracked vehicles.The vehicle is a complex nonlinear multi body system with numerous mobilities either in stiff and in elastic motion. For evaluating the vehicle performances, the maneuverability and stability behavior it is needed the availability of a model able to describe all the significant motion modes in different operative conditions. The paper presents the PICAV model and some results of the simulation campaign that demonstrated its soundness and reliability. © 2015, North Atlantic University Union NAUN. All rights reserved.
Signature verification on the basis of dynamic attributes (1999)

Presented at the National Conference of Student's Scholarly Circles (in Hungarian language)
Intrusion Detection for Industrial Control Systems by Machine Learning using Privileged Information (2021)

The continuous operation of an industrial process, such as water treatment or power generation, is governed by an Industrial Control System (ICS). Cyber-attacks on industrial networks are of growing concern because of the disruption they can cause, leading to loss of revenue, and the possibility of harm to workers, plant and surroundings. Operators therefore need a Network Intrusion Detection System (NIDS) to analyse industrial network traffic in real time for adversarial behaviour. Machine Learning (ML) is applicable to the problem of network intrusion detection. This paper investigates the possibility of training an ML-based NIDS for an ICS (specifically, the well-known Secure Water Treatment testbed) by combining network traffic data and physical process data. In the supplied dataset, data had already been labelled &#x201C;according to normal and abnormal behaviours&#x201D;; the labelling of data collected around the start and end of each attack was scrutinized and, where found to be problematic, labelled data were excluded in order to improve the effectiveness of supervised learning. The ML technique of &#x201C;Learning using Privileged Information&#x201D; was evaluated and found to be superior to six baseline ML algorithms trained on network traffic data alone.
Asymmetry of the Pitch Vestibulo‐Ocular Reflex in Patients with Cerebellar Disease (2005)

Responses to pitch head impulses were measured in 15 patients with cerebellar degeneration and downbeat nystagmus and in 5 control subjects, using three-axis search coils. For each subject, response gains were calculated as (1) the ratio of instantaneous vertical eye velocity to pitch head velocity (at 30 ms and at 70 ms into the response), and (2) the ratio of peak eye velocity to peak head velocity. Gains varied more widely among patients. When calculated at 70 ms and using peak values, patients had higher gains for downward pitch, and normal subjects had symmetric gains. At 30 ms, gains were more symmetric in patients, but at that point control subjects actually had lower gains for downward pitch. Thus, the pitch gain ratio (ratio of downward gain to upward gain) was consistently greater in patients than in normal subjects. Because downward impulses were generally faster, eye velocities during downward and upward pitch for equivalent head speeds were also compared. Again, patients had higher gains for downward pitch. These results are consistent with the authors' hypothesis that cerebellar disease results in a higher sensitivity of anterior than posterior semicircular canal pathways, perhaps through loss of inhibition from the flocculus/paraflocculus complex on anterior canal secondary neurons in the vestibular nuclei. The pitch gain asymmetry was larger than, and did not correlate with, the velocity of spontaneous upward drift. This supports the notion that other mechanisms are likely to contribute to downbeat nystagmus in these patients.
Distributed source coding using symbol-based and non-binary turbo codes – applications to wireless sensor networks (2008)

A simple but powerful scheme for distributed source coding (DSC) based on the concept of binning and syndromes and non traditional turbo codes is proposed. The previous works on the compression with side information using turbo codes and the binning technique are focused on binary turbo codes. The source is considered to be binary or is converted to a binary stream. This conversion, however, reduces the redundancy that could be exploited by the compression algorithm. To achieve higher compression efficiency, the authors propose using a scheme based on a turbo decoder that decides over symbols rather than bits. In the same direction and for further performance improvement, at the cost of increased encoder complexity, they also present a DSC scheme based on non-binary turbo codes. The results demonstrate improved performance. Based on the suggested algorithms, a scheme for gathering real data in wireless sensor networks and assess the corresponding energy savings is proposed.
Evidence from 31P Nuclear Magnetic Resonance that Polyphosphate Synthesis is a Slip Reaction in Paracoccus denitrificans (1979)

Conference Article| February 01 1979 Evidence from 31P Nuclear Magnetic Resonance that Polyphosphate Synthesis is a Slip Reaction in Paracoccus denitrificans STUART J. FERGUSON; STUART J. FERGUSON * 1Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, U.K. Search for other works by this author on: This Site PubMed Google Scholar DAVID G. GADIAN; DAVID G. GADIAN 1Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, U.K. Search for other works by this author on: This Site PubMed Google Scholar DOUGLAS B. KELL DOUGLAS B. KELL † 2Botany School, University of Oxford, South Parks Road, Oxford OX1 3RA, U.K. Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1979) 7 (1): 176–179. https://doi.org/10.1042/bst0070176 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Citation STUART J. FERGUSON, DAVID G. GADIAN, DOUGLAS B. KELL; Evidence from 31P Nuclear Magnetic Resonance that Polyphosphate Synthesis is a Slip Reaction in Paracoccus denitrificans. Biochem Soc Trans 1 February 1979; 7 (1): 176–179. doi: https://doi.org/10.1042/bst0070176 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search © 1979 Biochemical Society1979 Article PDF first page preview Close Modal You do not currently have access to this content.
Activation energy and prefactor for surface electromigration and void drift in Cu interconnects (2007)

Surface electromigration rates on oxide-free surfaces of unpassivated damascene Cu interconnect segments have been determined through electromigration testing under vacuum. Electromigration-induced voids grew at the cathode end of the segments due to a flux divergence at refractory-metal-lined vias to the lead lines below the test segment. Copper diffusivity on a clean Cu surface was determined by measuring the size of the voids as a function of time and test temperature at a fixed current. An activation energy of 0.45±0.11eV and a prefactor of 3.35×10−12m2∕s were found for the product of the effective charge z* and the surface diffusivity Ds. This result is shown to be consistent with void drift rates measured in passivated interconnects.
Imine Amidation Catalyzed by a Chiral VAPOL Calcium Phosphate (2020)

Over the last 16 years, chiral phosphoric acids (CPAs) have been shown to be excellent asymmetric catalysts, very effectively used in constructing chiral molecules with high enantiocontrol. In 2010, Ishihara et al. discovered that chiral metal phosphate complexes (or salts) could be found in substantial quantities, as contaminates, in some reported CPA-catalyzed reactions (Hatano, M.; Moriyama, K.; Maki, T.; Ishihara, K. <i>Angew. Chem., Int. Ed.</i> 2010, 49, 3823-3826). These metal phosphates were shown to actually catalyze the reactions in addition to CPAs. In this work, we have investigated in depth a reaction first reported to be catalyzed by CPAs based on a vaulted bis-phenanthrol (VAPOL) backbone. We have found that VAPOL metal phosphates were, in fact, superior catalysts for this reaction. Upon optimization, a wide substrate scope, low catalyst loading, and mild conditions could provide intermolecular imine amidation reactions producing chiral <i>N</i>,<i>N</i>'-aminal products in high yields and with excellent <i>ee</i> values (up to >99% yield, >99% <i>ee</i>).
ChemInform Abstract: A New Chiral Glycine‐Cation Equivalent. Asymmetric Synthesis of Optically Pure β‐Amino Alcohols and α‐Amino Esters. (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Über blutgerinnungshemmende Substanzen (1946)

Abstrakt Es wurden Schwefelsäureester polymerhomologer Reihen von Cellulosen, Polyvinylalkoholen, Stärken und Glykogenen hergestellt und auf ihre dem Heparin ähnliche blutgerinnungshemmende Wirksamkeit sowie ihre Toxizität untersucht, um den Einfluß von Molekülgestalt und Molekülgröße zu studieren. Es ergab sich, daß die unverzweigten Cellulosen und Polyvinylalkohole sehr wirksam sind, während die verzweigten Stärken und kugeligen Glykogene die Blutgerinnung wesentlich weniger, z. Tl. gar nicht hemmen. Bei den unverzweigten Produkten nimmt die Wirksamkeit mit steigendem Molekular-, gewicht in geringem Maße ab, die Toxizität ganz erheblich zu. Größte Wirksamkeit und geringste Toxizität fanden sich bei Fadenmolekülen mit Polymerisationsgraden zwischen etwa 20 und 80. Im Xylanschwefelsäureester wurde eine sehr wirksame und nahezu untoxische Substanz gefunden, die bereits klinisch mit Erfolg bei akuter Thrombose verwandt werden konnte
Measurement of the echo reduction for passive materials based on inverse filtering technique (2016)

A method of measuring the echo reduction of passive materials based on inverse filtering technique is presented. In this method, a received signal which contains circuit channel and underwater acoustic channel information is obtained by transmitting the initial pilot signal and receiving signals through the hydrophone. With inverse filtering technique, the channel transfer function between the transducer array and hydrophone can be calculated. Then, the inverse function of the transfer function can be obtained by a robust inversion method. By retransmitting the inverse function, the spatial and temporal pulse focus at the position of the hydrophone is achieved. Simulation examples of the inverse filtering show its high performance at the pulse compression and reverberation suppression. A steel plate sample with the size of 1.2m×1.6m×0.028m is tested in a wave guide tank. The method is demonstrated by the comparison of the theoretical and the experimental results in the measured frequency ranges from 1 to 5 kHz.
Confronting Grand Challenges in Environmental Fluid Mechanics (2019)

Environmental fluid mechanics underlies a wealth of natural, industrial and, by extension, societal challenges. In the coming decades, as we strive towards a more sustainable planet, there are a wide range of grand challenge problems that need to be tackled, ranging from fundamental advances in understanding and modeling of stratified turbulence and consequent mixing, to applied studies of pollution transport in the ocean, atmosphere and urban environments. A workshop was organized in the Les Houches School of Physics in France in January 2019 with the objective of gathering leading figures in the field to produce a road map for the scientific community. Five subject areas were addressed: multiphase flow, stratified flow, ocean transport, atmospheric and urban transport, and weather and climate prediction. This article summarizes the discussions and outcomes of the meeting, with the intent of providing a resource for the community going forward.
The SARS‐unique domain (SUD) of SARS‐CoV and SARS‐CoV‐2 interacts with human Paip1 to enhance viral RNA translation (2021)

The ongoing outbreak of severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2) demonstrates the continuous threat of emerging coronaviruses (CoVs) to public health. SARS-CoV-2 and SARS-CoV share an otherwise non-conserved part of non-structural protein 3 (Nsp3), therefore named as "SARS-unique domain" (SUD). We previously found a yeast-2-hybrid screen interaction of the SARS-CoV SUD with human poly(A)-binding protein (PABP)-interacting protein 1 (Paip1), a stimulator of protein translation. Here, we validate SARS-CoV SUD:Paip1 interaction by size-exclusion chromatography, split-yellow fluorescent protein, and co-immunoprecipitation assays, and confirm such interaction also between the corresponding domain of SARS-CoV-2 and Paip1. The three-dimensional structure of the N-terminal domain of SARS-CoV SUD ("macrodomain II", Mac2) in complex with the middle domain of Paip1, determined by X-ray crystallography and small-angle X-ray scattering, provides insights into the structural determinants of the complex formation. In cellulo, SUD enhances synthesis of viral but not host proteins via binding to Paip1 in pBAC-SARS-CoV replicon-transfected cells. We propose a possible mechanism for stimulation of viral translation by the SUD of SARS-CoV and SARS-CoV-2.
Origin of enhanced magnetoresistance of magnetic multilayers: Spin-dependent scattering from magnetic interface states (1993)

The origin of giant magnetoresistance exhibited by ferromagnetic/nonmagnetic multilayered structures is examined by inserting thin layers of a second ferromagnetic material at the interfaces in ferromagnetic/nonmagnetic/ferromagnetic sandwiches. It is generally observed, for many different combinations of metals, that the magnetoresistance depends exponentially on the thickness of the interface layer, with a characteristic length, \ensuremath{\xi}. \ensuremath{\xi} is extremely short and is typically just \ensuremath{\simeq}1.5 to 3 \AA{} at room temperature. At lower temperatures \ensuremath{\xi} becomes even shorter. The giant magnetoresistance effect is thus clearly shown to be determined by the character of the ferromagnetic/nonmagnetic interfaces.
Imaging Particle Temperatures and Curtain Opacities Using an IR Camera (2020)

Abstract The Falling Particle Receiver (FPR) at the National Solar Thermal Test Facility (NSTTF) is a testbed for promising receiver technologies offering solutions to the temperature and irradiance limitations exhibited by gas and molten salt receivers, since the particle curtain is directly irradiated without the need of containment. Until recently, the heat loss of the NSTTF 1 MWth FPR was not fully characterized. One of the challenges of the FPR characterization is the intricate flow conditions that the particle curtain experiences due to its cavity design with a single open aperture, to allow the direct irradiance. Recently, particle plumes expelled from the FPR during operation were observed. While this phenomenon affects the FPR heat loss and needs to be closely monitored, it is extremely difficult to operate any kind of sensors near the aperture of the FPR. This work describes the development of a methodology using a high-speed IR camera, located ≥ 5 meters away from the aperture, to estimate the opacity of a particle plume, which in turn can be used to extract the average particle temperature of a region of interest with a known background temperature. Experiments performed at the University of New Mexico using four different flow configurations and three different temperatures (200, 450, and 750°C) were conducted to determine the relationship between the plume opacity in the visible range and the “particle-pixel” opacity obtained from thermograms in the IR range. We present a “particle-pixel function” that describes the combined impact of an unknown number of particles at a specific temperature on a thermogram pixel value with an initial value equal to the background temperature. The novelty of this function is that it provides a reasonable estimate of the plume opacity using thermograms obtained from the IR camera; hence a bulk particle temperature can be obtained. Future development of this methodology will make it possible to compute the advective losses from the FPR and provide a first order approximation of the convective losses for the system.
[Study of N-nitroso compounds which have NO-release ability]. (1997)

Nitric oxide (NO), which plays an important role in the vital functions of organisms, is gaseous and labile molecule. Much attention has been paid to the stability and easily handling of NO donors, for careful handling of NO is required during experimental work. We synthesized a series of aromatic N-nitrosoureas and N-nitrosamides which efficiently liberates NO at room temperature. Generation of NO from the aromatic N-nitroso compounds was chemically confirmed by the trapping of NO as a nitrosyl complex of tetraphenylporphyrinatocobalt (II) and spectrophotometrically quantified by means of the Griess reaction using a newly designed test apparatus. 3,3-Dibenzyl-1-(4-tolyl)-1-nitrosourea showed the greatest NO-generating ability among the synthesized N-nitroso compounds. Further, the NO-generating ability was related to the reciprocal of the ID50 value for growth inhibition of cultured L-5178Y cell by the aromatic N-nitroso compounds.
Bright Light Therapy (1999)

The dominant effect of light treatment was improvement in bothersome symptoms. Although patients should be advised of side effects and guided in dose manipulations to reduce them, attention also should be drawn to the substantial benefit-to-risk ratio. Improvement of symptoms outside the depressive cluster, seen in both responders and nonresponders, may point to new therapeutic uses of light therapy.
The Trithorax group protein dMLL3/4 instructs the assembly of the zygotic genome at fertilization (2018)

ABSTRACT The transition from fertilized oocyte to totipotent embryo relies on maternally-provided factors that are synthetized and accumulated in developing oocytes. Yet, it is still unclear how oocytes regulate the expression of these embryo fate-promoting genes within the general transcriptional program of oogenesis. Here we report that the Drosophila Trithorax group protein MLL3/4 (dMLL3/4, also known as Trr) is essential for the transition to embryo fate at fertilization. In the absence of dMLL3/4, oocytes develop normally but fail to initiate the embryo mitotic divisions after fertilization. This incapability results from defects in both paternal genome reprogramming and maternal meiotic completion. We show that, during oogenesis, dMLL3/4 promotes the expression of a functionally coherent gene subset that is later required for the correct assembly of the zygotic genome. Accordingly, we identify the evolutionarily-conserved IDGF4 glycoprotein (known as oviductin in mammals) as a new oocyte-to-embryo transition gene under dMLL3/4 transcriptional control. Based on these observations, we propose that dMLL3/4 plays an instructive role in the oocyte-to-embryo transition that is functionally uncoupled from the requirements of normal oocyte differentiation.
Preoperative platelet count and volume could not help predict PONV in women undergoing breast cancer surgery: A prospective cohort study (2015)

One third of patients' experienced PONV, increased incidence associated to Apfel score but platelet numbers and simple platelet test provided no additional information around risk for PONV.