gebhart/patrepeval huggingface dataset:
Etude des carrières des ingénieurs de l'Ecole nationale supérieure de Chimie de Toulouse (1969)

The careers of former students at the « Ecole Nationale Supérieure de Chimie de Toulouse » (E.N.S.C.T. ) have been studied as part of research into training-employment relationships. There are four criteria of analysis: geographical, demographical, educational, socio-professional. Two methods have been used alongside each other: 1° Transversal analysis covers population distribution at different dates, according to the above criteria. 2° Analysis of groups makes it possible to follow the same individuels throughout their careers and thus shows what types of behaviour make adaptation possible. This twofold analysis shows that engineers who have been to a specialised school do, for most of their lives, fulfil functions which are closely related to their specialisation ; furthermore, institutional changes can alter the course of the post-training flow.
Influence of organic amendments on phytostabilization of Cd-contaminated soil by Eucalyptus camaldulensis (2016)

Greenhouse and field experiments were conducted to evaluate the influence of three different organic amendments (cow manure, pig manure, and organic fertilizer) on the Cd phytostabilization potential of Eucalyptus camaldulensis grown on Cd-contaminated soil. The application of all amendments, particularly organic fertilizer, improved plant growth (i.e., height and biomass production) when compared to the control (Cd-contaminated soil alone), in both greenhouse and field experiments. E. camaldulensis treated with organic fertilizer experienced the greatest height (39 cm and 3.8 m) and biomass production (2.0 g and 3.3 kg) in greenhouse and field experiments, respectively. Plants grown on amended soils had lower Cd accumulation than those grown on the Cd soil alone. Among the treatments, organic fertilizer resulted in a translocation factor < 1 and a bioconcentration factor for the root (BCFR) > 1, indicating the potential of this species to stabilize Cd in the roots. The results showed that E. camaldulensis is a promising species for phytostabilization of Cd-contaminated soil. The wood of the mature tree is used in the manufacture of commercial products; given the low Cd uptake by E. camaldulensis, it is feasible to harvest the wood grown on Cd-affected soils for making paper and furniture.
Structural Organization and Regulation of Antibiotic Biosynthesis and Resistance Genes in Actinomycetes (2020)

Streptomycetes, and presumably other actinomycetes, contain circular genomes about 1.5 to 2.0 times the size of the Escherichia coli genome. Since E. coli can transcribe about 2240 genes, streptomycete genomes may contain 3300 or more genes. Most actinomycetes undergo complex morphological differentiation, and this would account for some of the excess coding capacity. Many streptomycetes contain plasmids, and in at least one well-documented case, a selftransmissible plasmid contained antibiotic biosynthetic genes. Clustering of antibiotic biosynthetic genes is also of important practical significance. If one gene can be isolated by cloning, then the adjacent genes can be readily obtained. Beta-Lactam antibiotics, including penicillins, cephamycins, oxypenems, carbapenems, carbapenams, and nocardicins, are produced by a number of actinomycetes, including several species of Streptomyces.
Synthesis and interconversion by hydrogen exchange of isomeric quinhydrones (1977)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and interconversion by hydrogen exchange of isomeric quinhydronesGautam R. Desiraju, David Y. Curtin, and Iain C. PaulCite this: J. Org. Chem. 1977, 42, 25, 4071–4075Publication Date (Print):December 1, 1977Publication History Published online1 May 2002Published inissue 1 December 1977https://pubs.acs.org/doi/10.1021/jo00445a018https://doi.org/10.1021/jo00445a018research-articleACS PublicationsRequest reuse permissionsArticle Views262Altmetric-Citations19LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Frequency-based detection of replay attacks: application to a quadrotor UAV (2019)

Unmanned aerial vehicles (UAVs) are reported to be highly exposed as possible targets of cyber attacks, due to their strong strategic and economic value, and their increasing use in a wide range of operations. Among the most critical cyber attacks, replay attacks are performed by replacing the real data coming from the sensors with previously recorded data. In this way, the attacker may provoke performance degradation, cause instability, and allow to perform undetectable physical attacks. The main contribution of this paper is to investigate the applicability of a frequency-based detection method, which uses a sine wave with time-varying frequency as authentication signal, to a UAV affected by replay attacks. The effectiveness of the method is illustrated through simulation scenarios.
Low-Complexity Design and Validation of Wireless Motion Sensor Node to Support Physiotherapy (2020)

We present a motion sensor node to support physiotherapy, based on an *imu. The node has wireless interfaces for both data exchange and charging, and is built based on commodity components. It hence provides an affordable solution with a low threshold to technology adoption. We share the hardware design and explain the calibration and validation procedures. The sensor node has an autonomy of 28 h in operation and a standby time of 8 months. On-device sensor fusion yields static results of on average 3.28∘ with a drift of 2∘ per half hour. The final prototype weighs 38 g and measures 6 cm ×1.5 cm. The resulting motion sensor node presents an easy to use device for both live monitoring of movements as well as interpreting the data afterward. It opens opportunities to support and follow up treatment in medical cabinets as well as remotely.
Oxidative Cross-Coupling of β,β-Difluoroenol Silyl Ethers with Nucleophiles:  A Dipole-Inversion Method to Difluoroketones (2004)

Oxidative cross-coupling of alpha-aryl-beta,beta-difluoroenol silyl ethers with heteroaromatics in the presence of Cu(OTf)(2) in wet acetonitrile proceeds smoothly, affording heteroaryldifluoromethyl aryl ketones in 61-88% yields. Alcohols also react as nucleophiles under the same conditions to provide alkoxydifluoromethyl aryl ketones in 73-80% yields. [reaction: see text]
In Vitro Microbicidal Activities of Cecropin Peptides D2A21 and D4E1 and Gel Formulations Containing 0.1 to 2% D2A21 against Chlamydia trachomatis (2002)

Topically applied microbicides that eradicate pathogens at the time of initial exposure represent a powerful strategy for the prevention of sexually transmitted infections. To aid in the further development of an effective topical microbicide, we assessed the minimum cidal concentration (MCC) of two cecropin peptides, D2A21 and D4E1, and gel formulations containing 0.1 to 2% D2A21 against Chlamydia trachomatis in vitro. The MCC of peptide D2A21 was 5 microM (18.32 microg/ml), and that of peptide D4E1 was 7.5 microM (21.69 microg/ml). The MCC of gel formulations containing 2% D2A21 was 0.2 mM (0.7 mg/ml), and that of gel formulations containing 0.5% D2A21 was 0.2 mM (0.7 mg/ml). There was no significant variation in the results when two different C. trachomatis strains were tested, and the addition of 10% human blood did not significantly alter the MCCs. pH values above and below 7 reduced the activity of the D2A21 peptide alone, but the MCC of the 2% D2A21 gel formulation was only slightly altered at the various pHs tested. Ultrastructural studies indicated that C. trachomatis membranes were disrupted after D2A21 exposure, resulting in leakage of the cytoplasmic contents. These in vitro results suggest that these cecropin peptides may be an effective topical microbicide against C. trachomatis and support the need for further evaluation.
Impaired [Ca2+]i and secretory responses to ouabain in pancreatic islet cells from rats depleted in long-chain polyunsaturated omega-3 fatty acids (2008)

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Open architecture data system for NASA Langley Combined Loads Test System (1998)

The Combined Loads Test System (COLTS) is a new structures test complex that is being developed at NASA Langley Research Center (LaRC) to test large curved panels and cylindrical shell structures. These structural components are representative of aircraft fuselage sections of subsonic and supersonic transport aircraft and cryogenic tank structures of reusable launch vehicles. Test structures are subjected to combined loading conditions that simulate realistic flight load conditions. The facility consists of two pressure-box test machines and one combined loads test machine. Each test machine possesses a unique set of requirements or research data acquisition and real-time data display. Given the complex nature of the mechanical and thermal loads to be applied to the various research test articles, each data system has been designed with connectivity attributes that support both data acquisition and data management functions. This paper addresses the research driven data acquisition requirements for each test machine and demonstrates how an open architecture data system design not only meets those needs but provides robust data sharing between data systems including the various control systems which apply spectra of mechanical and thermal loading profiles.
From Pollutant to Chemical Feedstock: Valorizing Carbon Dioxide through Photo- and Electrochemical Processes (2022)

ADVERTISEMENT RETURN TO ISSUEEditorialNEXTFrom Pollutant to Chemical Feedstock: Valorizing Carbon Dioxide through Photo- and Electrochemical ProcessesJinwoo Cheon*Jinwoo CheonYonsei University*Email: [email protected]More by Jinwoo Cheonhttps://orcid.org/0000-0001-8948-5929, Jenny Y. Yang*Jenny Y. YangUC Irvine*Email: [email protected]More by Jenny Y. Yanghttps://orcid.org/0000-0002-9680-8260, Marc Koper*Marc KoperLeiden University*Email: [email protected]More by Marc Koperhttps://orcid.org/0000-0001-6777-4594, and Osamu Ishitani*Osamu IshitaniTokyo Institute of Technology*Email: [email protected]More by Osamu Ishitanihttps://orcid.org/0000-0001-9557-7854Cite this: Acc. Chem. Res. 2022, 55, 7, 931–932Publication Date (Web):April 5, 2022Publication History Received4 March 2022Published online5 April 2022Published inissue 5 April 2022https://pubs.acs.org/doi/10.1021/acs.accounts.2c00129https://doi.org/10.1021/acs.accounts.2c00129editorialACS PublicationsCopyright © Published 2022 by American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views3615Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (580 KB) Get e-AlertscloseSUBJECTS:Catalysts,Electrical energy,Fossil fuels,Inorganic carbon compounds,Oxides Get e-Alerts
[The occurrence of a reductase of delta2-carboxylic acids in Clostridium kluyveri with a stereospecificity different from that of butyryl-CoA dehydrogenase (author's transl)]. (1975)

A Clostridia strain (R-strain) which hydrogenates tiglinate (1b) and alpha-methylcinnamate (1c) in the presence of hydrogenase gas in 2H2O to (2R, 3S)2-methyl-[2,3-2H]butyrate (5b, H = 2H) and (alphaR, betaR)alpha-methyl[alpha,beta-2H]dihydrocinnamate (5c, H = 2H), respectively, was isolated. The configuration at C-3 was determined by 1H-NMR spectroscopy in the presence of Eu(fod)3. The stereochemistry of this hydrogenation is the mirror image of that which has been determined with intact cells of another strain of Clostridium kluyveri (S-strain). In the presence of hydrogen gas, the R-strain hydrogenates crotonate in 2H2O to butyrate with the following deuterium distribution: C-2, 1.85; C-3, 1.35; and C-4, 0.63 deuterium atoms. Crotonate seems to be the substrate of two reductases with sterically different actions. Tiglinate (1b) and alpha-methylcinnamate, however, are hydrogenated only by that reductase which is different from the butyryl-CoA dehydrogenase.
Choosing a Silicone Encapsulant for Photovoltaic Applications (2011)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Michelle Velderrain; Choosing a Silicone Encapsulant for Photovoltaic Applications: As presented at the CPV‐7 Conference in Las Vegas, NV; April 4‐6. AIP Conf. Proc. 1 December 2011; 1407 (1): 79–83. https://doi.org/10.1063/1.3658299 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
Poly(sulfobetaine) versus Poly(N-isopropylmethacrylamide): Co-Nonsolvency-Type Behavior of Thin Films in a Water/Methanol Atmosphere (2021)

The swelling and co-nonsolvency behaviors in pure H2O and in a mixed H2O/CH3OH vapor atmosphere of two different polar, water-soluble polymers in thin film geometry are studied in situ. Films of a zwitterionic poly(sulfobetaine), namely, poly[3-((2-(methacryloyloxy)ethyl)dimethylammonio) propane-1-sulfonate] (PSPE), and a polar nonionic polymer, namely, poly(N-isopropylmethacrylamide) (PNIPMAM), are investigated in real time by spectral reflectance (SR) measurements and Fourier transform infrared (FTIR) spectroscopy. Whereas PSPE is insoluble in methanol, PNIPMAM is soluble but exhibits co-nonsolvency behavior in water/methanol mixtures. First, the swelling of PSPE and PNIPMAM thin films in H2O vapor is followed. Subsequently, CH3OH is added to the vapor atmosphere, and its contracting effect on the water-swollen films is monitored, revealing a co-nonsolvency-type behavior for PNIPMAM and PSPE. SR measurements indicate that PSPE and PNIPMAM behave significantly different during the H2O swelling and subsequent exposure to CH3OH, not only with respect to the amounts of absorbed water and CH3OH, but also to the cosolvent-induced contraction mechanisms. While PSPE thin films exhibit an abrupt one-step contraction, the contraction of PNIPMAM thin films occurs in two steps. FTIR studies corroborate these findings on a molecular scale and reveal the role of the specific functional groups, both during the swelling and the cosolvent-induced switching of the solvation state.
Translocation of Mitochondrial HSP60 Precedes Cytochrome C Release Following Cerebral Hypoxic‐Ischemic Injury in the Neonatal Rat: A Role in Apoptosis Induction? (2013)

The mitochondrial HSP60 is unique among the family of heat shock proteins in that it has pro‐survival and pro‐apoptotic functions. Here we demonstrate that translocation of HSP60 occurs during/immediately following hypoxic‐ischemic (HI) insults to the neonatal rat brain. We employed a rat model of neonatal Encephalopathy, in which 7day old pups underwent unilateral common carotid artery ligation followed by 120min of hypoxia (8% O 2 ). Injury was assessed using triphenyltetrazolium chloride staining 24hour after HI. The hemisphere ipsilateral to the ligation (hypoxic‐ischemic) exhibits a robust injury comprising 30% of the hemisphere with primarily cortical involvement. Notably, the hemisphere contralateral to the ligation (hypoxic) is uninjured. To examine the effects of cerebral HI on cytosolic accumulation HSP60 and cytochrome C (cytoC), mitochondrial and cytosolic fractions were isolated via differential centrifugation immediately following the insult and after 4hrs of recovery. Samples were analysed via western blot. Normoxic, uninjured littermates were used as controls. HI results in a 2× increase of HSP60 immunoreactivity in the cytosol immediately following the insult. Furthermore, cytoC release was not observed at this early time point. These data suggest that translocation of HSP60 may play a role in the induction of apoptosis following cerebral HI in the neonatal rat.
A 1-V 7th-Order SC Low-Pass Filter for 77-GHz Automotive Radar in 28-nm FD-SOI CMOS (2021)

This paper presents a switched capacitor low-pass filter in a 28-nm fully depleted silicon on insulator CMOS technology for 77-GHz automotive radar applications. It is operated at a power supply as low as 1 V and guarantees 5-dB in-band voltage gain while providing out-of-band attenuation higher than 36 dB and a programmable passband up to 30 MHz. A double sampling technique is adopted, which allows high operating frequency to be achieved while saving power. Moreover, low-voltage biasing and common-mode feedback circuits are exploited to guarantee an almost rail-to-rail output voltage swing. The proposed filter provides an output 1-dB compression point as high as 8.7 dBm with a power consumption of 9 mW. To the authors’ knowledge, this is the first SC-based implementation of a low pass filter for automotive radar applications.
5‐HT2B receptors play a key role in mediating the excitatory effects of 5‐HT in human colon in vitro (2002)

1. 5-Hydroxytryptamine (5-HT) is known to produce a number of different effects in the gastrointestinal tract of various species, and has been proposed to play a key role in a number of intestinal disorders in man, including irritable bowel syndrome (IBS), although the receptors involved have yet to be established. The aim of the present study was to investigate the distribution and function of 5-HT(2B) receptors in human colon, and to establish their possible role in the aetiology of IBS. 2. The distribution of 5-HT(2B) receptor mRNA and protein were investigated by quantitative RT - PCR, Western analysis and immunocytochemistry. High levels of both mRNA and protein for 5-HT(2B) receptors were found throughout the human gastrointestinal tract, and in particular in colon, where 5-HT(2B) receptors were found predominantly in the longitudinal and circular smooth muscle layers within the muscularis externa, and in the myenteric nerve plexus lying between these two layers. 3. Electrical field stimulation of longitudinal muscle preparations of human colon mounted in organ baths resulted in neuronally-mediated contractile responses, that were significantly potentiated by application of 5-HT (up to 10(-7) M), with a pEC(50) of 8.2 +/- 0.1 (n=49 donors). The response to 5-HT was inhibited by a number of selective 5-HT(2B) receptor antagonists. 4. This study has shown for the first time that, in contrast to animal studies, the excitatory effects of 5-HT in human colon are mediated by 5-HT(2B) receptors. It is proposed that these receptors contribute to the putative 5-HT-induced colonic smooth muscle hypersensitivity associated with IBS.
Atomic ordering-induced band gap reductions in GaAsSb epilayers grown by molecular beam epitaxy (2005)

A series of GaAs1−xSbx epilayers (0.51&amp;lt;x&amp;lt;0.71) grown by molecular-beam epitaxy on GaAs substrates with surface orientations of (001), (001) −8° toward (111)A, (001) −8° toward (111)B, (115)A, (115)B, (113)A, and (113)B were investigated using temperature-dependent Fourier transform infrared (FTIR) spectroscopy and transmission electron microscopy. Atomic ordering in these epilayers was observed from a decrease in the energy gap measured by FTIR absorption and corroborated by superlattice reflections in electron diffraction. Contrary to previous investigations of ordering in III-V alloys, a marked energy-gap reduction, corresponding to CuPt-B-type ordering, is observed in the GaAs1−xSbx grown on (111)A-type substrate offcuts.
Resilient emotionality and molecular compensation in mice lacking the oligodendrocyte-specific gene Cnp1 (2011)

Altered oligodendrocyte structure and function is implicated in major psychiatric illnesses, including low cell number and reduced oligodendrocyte-specific gene expression in major depressive disorder (MDD). These features are also observed in the unpredictable chronic mild stress (UCMS) rodent model of the illness, suggesting that they are consequential to environmental precipitants; however, whether oligodendrocyte changes contribute causally to low emotionality is unknown. Focusing on 2'-3'-cyclic nucleotide 3'-phosphodiesterase (Cnp1), a crucial component of axoglial communication dysregulated in the amygdala of MDD subjects and UCMS-exposed mice, we show that altered oligodendrocyte integrity can have an unexpected functional role in affect regulation. Mice lacking Cnp1 (knockout, KO) displayed decreased anxiety- and depressive-like symptoms (i.e., low emotionality) compared with wild-type animals, a phenotypic difference that increased with age (3-9 months). This phenotype was accompanied by increased motor activity, but was evident before neurodegenerative-associated motor coordination deficits (≤ 9-12 months). Notably, Cnp1(KO) mice were less vulnerable to developing a depressive-like syndrome after either UCMS or chronic corticosterone exposure. Cnp1(KO) mice also displayed reduced fear expression during extinction, despite normal amygdala c-Fos induction after acute stress, together implicating dysfunction of an amygdala-related neural network, and consistent with proposed mechanisms for stress resiliency. However, the Cnp1(KO) behavioral phenotype was also accompanied by massive upregulation of oligodendrocyte- and immune-related genes in the basolateral amygdala, suggesting an attempt at functional compensation. Together, we demonstrate that the lack of oligodendrocyte-specific Cnp1 leads to resilient emotionality. However, combined with substantial molecular changes and late-onset neurodegeneration, these results suggest the low Cnp1 seen in MDD may cause unsustainable and maladaptive molecular compensations contributing to the disease pathophysiology.