gebhart/patrepeval huggingface dataset:
Reversible Encapsulation and Its Consequences in Solution (1998)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReversible Encapsulation and Its Consequences in SolutionJulius RebekView Author Information Skaggs Institute for Chemical Biology and Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037 Cite this: Acc. Chem. Res. 1999, 32, 4, 278–286Publication Date (Web):December 10, 1998Publication History Received7 October 1997Published online10 December 1998Published inissue 20 April 1999https://pubs.acs.org/doi/10.1021/ar970201ghttps://doi.org/10.1021/ar970201gresearch-articleACS PublicationsCopyright © 1999 American Chemical SocietyRequest reuse permissionsArticle Views2142Altmetric-Citations323LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Encapsulation,Molecules,Noncovalent interactions,Oligomers,Solvents Get e-Alerts
Bromocriptine inhibits norepinephrine release (1979)

Bromocriptine is a dopamine agonist that induces postural hypotension and can be used as an antihypertensive. The drug inhibits release of norepinephrine (NE) from an isolated artery by stimulating presynaptic receptors. In normotensive subjects it lowers both plasma and cerebrospinal fluid (CSF) levels of NE by 50% and lowers blood pressure moderately in standing subjects and slightly in recumbent subjects. Through central and peripheral mechanisms, bromocriptine inhibits sympathetic nervous discharge of NE.
Fabrication of Quantum Dots in Undoped SiGe with a single metal layer. (2016)

Abstract not provided.
(2E)-N′-Benzoyl-3-(4-nitrophenyl)prop-2-enohydrazide (2009)

In the title compound, C(16)H(13)N(3)O(4), the dihedral angle between the terminal benzene rings is 14.02 (7)°. The carbonyl groups are anti with respect to each other, which facilitates their participation in the formation of supra-molecular chains. Each side of the -C(=O)N(H)N(H)C(=O)- residue associates with a centrosymmetrically related mol-ecule, resulting in the formation of essentially flat ten-membered {⋯O=CNN(H)}(2) synthons. The resultant chains are further consolidated in the crystal structure via C-H⋯O contacts.
Inhibiting Browser Fingerprinting and Tracking (2017)

This paper discusses possible approaches to address the loss of user privacy when browsing the web and being tracked by websites which compute a browser fingerprint identifying the user computer. The key problem is that the current fingerprinting countermeasures are insufficient to prevent fingerprinting tracking and also frequently produce side-effects on the web browser. The advantages and disadvantages of possible countermeasures are discussed in the context of improving resistance against browser fingerprinting. Finally, using a new browser extension is proposed as the best way to inhibit fingerprinting as it could probably inhibit some of the fingerprinting techniques used and also diminish the side-effects on the user browser experience, compared with existing techniques.
Increased responsiveness of rheumatoid factor–producing B cells in seronegative and seropositive rheumatoid arthritis (1996)

B cell precursors with the potential to secrete RF were detectable in high frequencies in normal individuals and in patients with seropositive and seronegative RA. In all donors, these B cells could be stimulated with the bacterial superantigen SED. In normal individuals, RF+ B cells remained nonresponsive to help provided by anti-CD3-activated T cells, but were responsive in RA patients. Seronegative and seropositive RA form a continuous spectrum of disease, with a higher number of RF-secreting B cells in the seropositive patients.
Mångfald - retorik och organisationslogik i Malmö kommun (2004)

Med hjälp av en analys av kommunalrådsretorik och retoriken i mångfaldspolicyn&#13;\nför Malmö kommun diskuteras styrkor, svagheter och svårigheter&#13;\ni styrningen av etnisk mångfald i den kommunala organisationen.&#13;\nKommunens speciella organisatoriska karaktär, dess organisationslogik,&#13;\när en del av problemet med att implementera en mångfaldspolitik, den&#13;\nspeciella utmaningen i kommunens mångfaldsarbete. Variationen i reaktionsmönster&#13;\ni den kommunala organisation kan bland annat ses som en&#13;\neffekt brist på klara mål och kreativa metoder för implementeringen i en&#13;\nlöst kopplad organisation.
Investigation of Chemiluminescence Behavior of Flavonoids with Cerium (IV)‐Rhodamine B System (2006)

Abstract The chemiluminescence (CL) behavior of five major flavonoid types in cerium (IV)‐rhodamine B system was investigated by flow‐injection. Strong CL was observed when cerium (IV) reacted with rhodamine B in sulfuric acid medium in the presence of flavonoids. This reaction system has been established as a simple, rapid, and highly sensitive flow injection CL analysis for quercetin and kaempferol, and their detection limit (3σ) was 2.7 and 0.22 nmol/L, respectively. The relative standard deviation (n=8) was 1.2% for 1.0 µmol/L quercetin and 1.9% for 0.5 µmol/L kaempferol. This method was successfully applied to the determination of quercetin in the hydrolysate of rutin and compared well with the high performance liquid chromatography (HPLC) method. From a comparison of several related flavonoids, it was concluded that only flavonoids that contain a free 3‐hydroxyl and 2, 3‐double bond in conjugation with 4‐oxo function could produce a relatively strong CL emission.
Production of Aspartic Acid and Lysine by Citrate Synthase Mutants ofBrevibacterium flavum (1982)

A prototrophic revertant was derived from a citrate synthase-defective glutamate auxotroph of Brevibacterium flavum. It showed low citrate synthase activity and overproduced L-aspartic acid. The maximum production was 10.6 g/liter (about a 30% yield) when the strain was cultured in medium containing 36 g/liter of glucose for 48 hr. The amount of aspartic acid produced depended greatly on the concentration of biotin in the medium, as the case of glutamate production by the original wild strain. When the revertant strain was cultured with excess biotin, acetic acid accumulated instead of aspartic acid. A mutant resistant to S-(2-aminoethyl)-L-cysteine plus threonine derived from the revertant strain produced 36 g/liter of L-lysine (as hydrochloride salt) when it was cultured in medium containing 100 g/liter of glucose for 72 hr (36% yield). The amount of lysine production by this mutant was greater than those by the resistant mutants derived directly from the original wild strain. The frequency of the appearance of mutants which produced more than 30 g/liter of lysine was about one per 250 strains of resistant mutants. A high concentration of ammonium sulfate was required for a high yield of lysine production. A homoserine auxotroph derived from the revertant strain produced 33 g/liter of L-lysine (33% yield), which was almost the same amount as that derived directly from the original wild strain.
Effect of Hexadecanol and Octadecanol on Efficiency of Water Use and Growth of Corn1 (1962)

Synopsis There was no evidence that these materials could bring about a saving in water use by corn in the greenhouse.
Gas liquid chromatography-mas spectrometry of paraquat and diquat reduction products. A reductive cleavage of paraquat and diquat by NaBH4 in the presence of a transition metal salt (Ni2+). (1991)

When herbicide preparations paraquat(I) and diquat(II), based on N-alkylbipyridylium derivatives, were analyzed by gas liquid chromatography (GLC) with sodium borohydride (NaBH4)-nickel(II) chloride (NiCl2) reduction, the chromatograms showed minor side peaks from slight amounts of by-products appearing in front of the main peaks, arising from the respective perhydrogenated products of I or II.Reductive cleavage of a C-N bond within each pyridine ring of I or II was suggested in view of the production of trifluoroacetic acid derivatives prepared from these by-products.The by-products, whose structures were elucidated by GLC-mass spectrometry, were consequently presumed to be p-(N-methylaminopent-3'-yl)-N-methylpiperidine, arising from I, or 1 butyl-2-aza-perhydroquinolizine, arising from II.Correlation was also observed between the amounts of NaBH4 and NiCl2 and the production of by-products; the less NaBH4 and the more NiCl2 in a given volume of water, the greater the increase in side reaction products.The side peaks could not be observed on the gas-chromatogram when perhydrogenated products prepared separately from I and II were treated by NaBH4-NiCl2 reduction. The side peaks could be observed, however, when incomplete reduction products with one or two double bonds, obtained by reduction of I and II by NaBH4 alone, were reduced by NaBH4-NiCl2 reduction. It could therefore be presumed that this reductive cleavage at a C-N bond occurred, the intermediate state being the complex between nickel and incomplete reduction products with one or two remaining double bonds in the pyridine ring.
DNA synthesis errors associated with double-strand-break repair. (1995)

Repair of a site-specific double-strand DNA break (DSB) resulted in increased reversion frequency for a nearby allele. Site-specific DSBs were introduced into the genome of Saccharomyces cerevisiae by the endonuclease encoded by the HO gene. Expression of the HO gene from a galactose-inducible promoter allowed efficient DNA cleavage at a single site in large populations of cells. To determine whether the DNA synthesis associated with repair of DSBs has a higher error rate than that associated with genome duplication, HO-induced DSBs were generated 0.3 kb from revertible alleles of trp1. The reversion rate of the trp1 alleles was approximately 100-fold higher among cells that had experienced an HO cut than among uninduced cells. The reverted allele was found predominantly on the chromosome that experienced the DNA cleavage.
When do the availability codes make the stored data more available? (2015)

In distributed storage systems, a special sub-class of locally repairable codes, known as the availability codes, has been proposed to enable recovery of each data block from multiple, disjoint groups of nodes of small size. Availability codes, thus not only provide good fault tolerance and its efficient maintenance, but also allow access to data by simultaneous users. In this paper, we first analyze the impact of availability parameters, i.e., the size and the number of repair groups, on the download latency by computing the mean download time using multiple repair groups and the probability that repair groups perform slower download than the systematic node. Then, we explore the case when the cumulative service capacity of the system is limited, and determine the optimal service capacity allocation across nodes such that mean download delay of a single request is minimized. We consider capacity allocation problem under three traffic splitting models, which differ in what fraction of requests are routed to the node storing the desired data block and to one or more of its repair groups. Throughout, we assume that the download requests arrive at a low rate. We find that although, in principle, higher availability should help in reducing download delays, this is not the case in our scenario. This suggests the necessity to further investigate the impact of availability on download latency by exploring different arrival, service, and content access models.
Design of an agile unmanned combat vehicle: a product of the DARPA UGCV program (2003)

The unmanned ground compat vehicle (UGCV) design evolved by the SAIC team on the DARPA UGCV Program is summarized in this paper. This UGCV design provides exceptional performance against all of the program metrics and incorporates key attributes essential for high performance robotic combat vehicles. This performance includes protection against 7.62 mm threats, C130 and CH47 transportability, and the ability to accept several relevant weapons payloads, as well as advanced sensors and perception algorithms evolving from the PerceptOR program. The UGCV design incorporates a combination of technologies and design features, carefully selected through detailed trade studies, which provide optimum performance against mobility, payload, and endurance goals without sacrificing transportability, survivability, or life cycle cost. The design was optimized to maximize performance against all Category I metrics. In each case, the performance of this design was validated with detailed simulations, indicating that the vehicle exceeded the Category I metrics. Mobility metrics were analyzed using high fidelity VisualNastran vehicle models, which incorporate the suspension control algorithms and controller cycle times. DADS/Easy 5 3-D models and ADAMS simulations were also used to validate vehicle dynamics and control algorithms during obstacle negotiation.
Fluorochemical Mass Flows in a Municipal Wastewater Treatment Facility (2006)

Fluorochemicals have widespread applications and are released into municipal wastewater treatment plants via domestic wastewater. A field study was conducted at a full-scale municipal wastewater treatment plant to determine the mass flows of selected fluorochemicals. Flow-proportional, 24 h samples of raw influent, primary effluent, trickling filter effluent, secondary effluent, and final effluent and grab samples of primary, thickened, activated, and anaerobically digested sludge were collected over 10 days and analyzed by liquid chromatography electrospray-ionization tandem mass spectrometry. Significant decreases in the mass flows of perfluorohexane sulfonate and perfluorodecanoate occurred during trickling filtration and primary clarification, while activated sludge treatment decreased the mass flow of perfluorohexanoate. Mass flows of the 6:2 fluorotelomer sulfonate and perfluorooctanoate were unchanged as a result of wastewater treatment, which indicates that conventional wastewater treatment is not effective for removal of these compounds. A net increase in the mass flows for perfluorooctane and perfluorodecane sulfonates occurred from trickling filtration and activated sludge treatment. Mass flows for perfluoroalkylsulfonamides and perfluorononanoate also increased during activated sludge treatment and are attributed to degradation of precursor molecules.
Synthesis of Polymer-Supported Homosalen Ligand and its Application to Stereoselective Polymerization of Racemic Lactide (2013)

再利用可能かつポリマーが着色しないラセミラクチドのイソタクチック選択的重合触媒配位子として，ホモサレン配位子を市販のMerrifield樹脂に固定化した．まず適当な保護基を有する1,3-ジアミノプロパン-2-オール誘導体を用い，樹脂とカップリング反応を行った後，脱保護後して置換基を有するサリチルアルデヒドと脱水縮合により，固定化ホモサレン配位子を合成した．合成した固定化配位子をトリエチルアルミニウムと反応させ，触媒を調製した．過剰のトリエチルアルミニウムは，触媒調製の溶液部分を取り除くことにより容易に除去できた．こうして調製した固定化触媒を用い，アルミニウムに対して1当量のベンジルアルコール存在下，50当量のラセミラクチドと反応させたところ，イソタクチックポリマーが得られた．重合混合物にメタノールを含むトルエンを加えてろ過すると，配位子と粗生成物を分離することができた．ろ液には生成したポリマーと未反応のモノマーのみ含まれていた．回収した固定化高分子配位子は，再利用することが可能であった．
Discovery of Quinolinediones Exhibiting a Heat Shock Response and Angiogenesis Inhibition (2008)

A series of substituted quinoline-5,8-diones were synthesized and evaluated as inhibitors of the chaperone protein Hsp90 using two assays: competition for binding to C-terminal ATP-binding site and competition for binding to N-terminal ATP-binding site. In addition, the ability of the compounds to induce the heat shock response was determined using a reporter fibroblast cell line. Of all the compounds assayed, only 6-aziridinyl-2-biphenylquinoline-5,8-dione induced a heat shock response and did so without interacting at the ATP binding sites of Hsp90. COMPARE analysis was carried out on quinoline-5,8-diones active in the National Cancer Institute's 60-cell line screen with the goal of discovering quinoline-5,8-dione structures that interact with other cellular targets (molecular targets) important for cancer chemotherapy. COMPARE analysis led to the discovery of a combretastatin-like quinoline-5,8-dione structure that, in fact, inhibited angiogenesis.
Lateral Nonuniformity of the Tunneling Current of Al/SiO2/p-Si Capacitor in Inversion Region Due to Edge Fringing Field Effect (2013)

Interesting area and perimeter dependency mechanisms of dark gate current in Al/SiO 2 /p-Si capacitor is demonstrated. To study this lateral non-uniformity phenomenon, three different thicknesses of top aluminum gate are intentionally designed to our capacitors. According to C-V and I-V measurements carried out in the dark, it is found that the device with thin top Al-gate will result in entirely different electrical characteristics compared with the device with thick top Al-gate. Moreover, measurements with light illumination show that there is enhanced edge charge collection efficiency in inversion due to edge fringing field effect.
Effect of Ultrasonic Plastic Treatment on the Surface Structure and Phase State of Nickel Titanium (2005)

The influence of ultrasonic plastic treatment (UPT) on the relief, microstructure, and phase state of the surface of nickel titanium (TiNi) has been studied. The UPT leads to significant hardening, nanofragmentation, and a change in the phase state of the surface TiNi layer.
Headphone Virtualisation: Improved Localisation and Externalisation of Nonindividualised HRTFs by Cluster Analysis (2012)

Research and experimentation is described which aims to prove the hypothesis that by allowing a listener to choose a single non-individualised profile of HRTFs from a subset of maximally different best representative profiles extracted from a database, improved localisation and externalisation can be achieved for the listener. &amp;-means cluster analysis of entire impulse reponses is used to identify the subset of profiles. Experimentation in a controlled environment shows that test subjects who were offered a choice of a preferred HRTF profile were able to consistently discriminate between a front centre or rear centre virtualised sound source 78.6% of the time, compared with 64.3% in a second group given an arbitrary HRTF profile. Similar results were obtained from virtualisations in uncontrolled environments.
[Urinary bilharziasis and sideropenic anemia. Study of their relation in 2 villages in Niger]. (1985)

In order to assess Schistosoma haematobium as an aetiologic factor in sideropenic anaemias, we compared a village with high prevalence of urinary schistosomiasis and a village without urinary schistosomiasis as a control. In the infested village, anaemias (haemoglobin value lower than 12 g/dl) especially affects children between 5 to 14 years old (71%:45/68). Boys being the most infestated group with S. haematobium (prevalence:100%; mean egg output: 496 eggs/10 ml of urine) are also the most anaemic group (82%:23/28). Comparing the two villages shows that urinary schistosomiasis increases the risk of acquiring anaemia by 30% among children aged 5 to 14. Furthermore, the parasitic disease reduces of 1 g/dl the mean haemoglobin level of adult males. On the other hand, S. haematobium is of minor importance as a cause of anaemia among women. The others aetiologies remain preponderant.
Cooperative Amplify-and-Forward Beamforming with Multiple Multi-Antenna Relays (2011)

In this paper, we consider beamforming (BF) for cooperative networks with one multi-antenna source, multiple multi-antenna amplify-and-forward (AF) relays, and one single-antenna destination. The source BF vector and the AF-BF matrices at the relays are optimized for maximization of the signal-to-noise ratio (SNR) at the destination under three different power constraints. In particular, we consider individual relay power constraints, a joint relay power constraint, and a joint power constraint for the source and the relays. We solve the associated optimization problems in two stages. In the first stage, we find the optimal AF-BF matrices for a given BF vector at the source. For the cases of individual and joint relay power constraints, closed-form solutions for the AF-BF matrices are provided, respectively. Furthermore, for the case of a joint source-relay power constraint, the AF-BF matrices are obtained in closed form up to a scalar power allocation factor and an efficient numerical algorithm for the power allocation between the source and the relays is given. In the second stage, the optimal source BF vectors are computed. Thereby, we show that for the joint relay and the joint source-relay power constraints, the resulting problem can be transformed into a non-convex polynomial programming problem which allows for an exact solution for small-scale networks. For large-scale networks and networks with individual relay power constraints, we propose efficient suboptimal optimization methods for the source BF vector. Simulation results show the benefits of having multiple antennas at the source and/or multiple multi-antenna relays and illustrate the performance differences introduced by the three different power constraints.
Real-time Rendering of Layered Materials with Anisotropic Normal Distributions (2019)

This paper proposes a lightweight bidirectional scattering distribution function (BSDF) model for layered materials with anisotropic reflection and refraction properties. In our method, each layer of the materials can be described by a microfacet BSDF using an anisotropic normal distribution function (NDF). Furthermore, the NDFs of layers can be defined on tangent vector fields, which differ from layer to layer. Our method is based on a previous study in which isotropic BSDFs are approximated by projecting them onto base planes. However, the adequateness of this previous work has not been well investigated for anisotropic BSDFs. In this paper, we demonstrate that the projection is also applicable to anisotropic BSDFs and that they can be approximated by elliptical distributions using covariance matrices.
Statin use decreases coagulation in users of vitamin K antagonists (2016)

Initiation of statin treatment was associated with an immediate and long-term minor although statistically significant decrease in VKA dosage in both phenprocoumon and acenocoumarol users, which suggests that statins may have anticoagulant properties.
Critical Electric Field in BaTiO3 (1969)

The present theoretical analysis permits simple, rigorous calculation of the equilibrium properties of state of a ferroelectric possessing a first-order phase transition. The positive critical field in BaTiO3 is approximately 9×105 V/m. Experimental observation of the critical point should result in a better value for the temperature dependence of the fifth-order thermodynamic coefficient ζ.
Human variation database: an open-source database template for genomic discovery (2011)

afejes@bcgsc.ca.