gebhart/patrepeval huggingface dataset:
Millimeter-wave generation and digital modulation in an InGaAs-InP heterojunction phototransistor: model and experimental characterization of dynamics and noise (2001)

This paper describes the use of an InGaAs-InP photoheterojunction bipolar transistor (photo-HBT) for millimeter-wave generation and digital modulation. Optical mixing of two coherent signals generates the carrier, and a digital drive signal to the base is used for the modulation. We describe an advanced large signal model of the photo-HBT that takes into account distributed effects at high frequencies and all noise sources, including optical amplifier noise and noise correlations due to the high operation frequency and the nonlinear mixing processes. The model enables one to predict carrier-to-noise ratio dependence on frequency, optical power, and the transistor operating point. Frequency- and time-domain responses of the modulated millimeter- wave carrier and bit error rates are also calculated. Experiments at 10 and 45 GHz with modulation rates ranging between 50 Mb/s and 2.5 Gb/s were performed, and a superb fit to the calculated responses is found.
Ultra-Reliable Low-Latency Control Signaling in a Factory Environment (2020)

The recently released 3GPP Fifth Generation New Radio (5G NR), does not always meet ultra-reliable low-latency communication (URLLC) requirements that are becoming more necessary as massive machine-type communications (mMTC) evolve. Sixth Generation communications (6G) will implement URLLC solutions capable of satisfying a large spectrum of latency and reliability requirements. Currently, control channels implemented in 5G NR suffer from low spectral efficiency, hence, in a high traffic network may fail to satisfy the URLLC requirements. Cyclic prefixed direct sequence spread spectrum (CP-DSSS) is an LTE compatible waveform that has recently been proposed as a more efficient signaling that better satisfies the needs of URLLC. In this article, CP-DSSS is further developed and its usefulness to a 3GPP-proposed factory floor is presented through a system-level simulation.
THE BIONIC BACK (1993)

Urinary calcium/creatinine ratio (U Ca/creat) was studied in infants, term and preterm newborn babies. In 31 1.5-24 months old healthy infants, the median U Ca/creat was 0.16 mmol/mmol (range 0.013-1.17) and was similar to the value obtained in children older than 4 years. In 55 healthy full-term newborns studied in the first week of life, the median U Ca/creat was 0.12 mmol/mmol. However the range of values was extremely wide (0.0006-4.75), suggesting that the U Ca/creat ratio is of little interest to screen for hypercalciuria during the neonatal period. In 31 premature newborns, the median U Ca/creat was 1.08 mmol/mmol, a value significantly higher than in the two other groups (P < 0.001); as in the term newborns there was a very wide range of values (0.057-6.83). However after excluding the premature babies with elevated serum 25 OHD level, this difference was not statistically significant.
Absorción de colorantes directos sobre fibras de lyocell (2003)

La recente apparition de cette fibre presente les avantages d’un procede de fabrication moins polluant que celui de la viscose conventionnelle, tout en ameliorant les proprietes de resistance et de tenacite en milieu humide. Le comportement de la fibre lyocell par rapport a l’absorption de colorants directs revet une certaine importance dans la phase de teinture correspondante, pendant le traitement chimique et industriel de cette fibre.
L’etude vise a caracteriser les parametres influents dans le processus d’absorption de colorants directs sur les fibres de lyocell, a partir de l’analyse des isothermes d’absorption dans l’equilibre du colorant C.I. Direct Blue 1. A partir des resultats experimentaux, nous avons determine les equations d’equilibre pour l’interpretation du comportement du systeme en faisant une analyse comparative des equations proposees par Nernst, Freundlich et Langmuir et nous avons calcule le volume libre interne caracteristique de la fibre lyocell, V(l/kg). Nous avons egalement calcule les grandeurs thermodynamiques caracteristiques du systeme : affinite, entropie et entalpie standard de teinture, qui permettront de reproduire et de prevoir les resultats experimentaux de maniere satisfaisante, ainsi que de comparer quantita-tivement plusieurs alternatives d’operation, en obtenant l’information minimale necessaire pour evaluer comparativement le procede.
Chemical Radiculitis (1977)

Chemical radiculitis is an inflammatory condition of the nerve root due to the rupture of the annulus fibrosus and dissemination of disk fluid along the nerve root sheath. The inflammatory component of disk fluid is glycoprotein. The inflammation is a reaction to repeated injuries of the spinal column, as for example, in occupational lifting of heavy loads. Rupture of the annulus fibrosus and liberation of disk fluid into the tissues also evokes circulating antibody response and auto immune reaction. A high titer to glycoprotein at 3 weeks after an acute attack of back pain is evidence of the presence of a significant disk lesion. In selected cases immediate relief from pain occurs after administration of cortisone or a suitable cortisone-derivative. Prolonged rest may be contraindicated because of the risk of formation of radicular adhesions.
Evidence for Regulated Interleukin-4 Expression in Chondrocyte-Scaffolds under In Vitro Inflammatory Conditions (2011)

Regulated expression of therapeutic candidate gene(s) coupled with suitable scaffold(s) could potentially serve as a useful tissue-engineering tool to devise future treatment strategies for osteoarthritis.
Interactions of T7 RNA polymerase with T7 late promoters measured by footprinting with methidiumpropyl-EDTA-iron(II) (1987)

The interactions of T7 RNA polymerase with T7 late promoters were studied by using quantitative footprinting with methidiumpropyl-EDTA X Fe(II) [MPE-Fe(II)] as the DNA cleaving agent. Class II and class III T7 promoters have a highly conserved 23 base pair sequence from -17 to +6. Among class III promoters the -22 to -18 region is also highly conserved. For a class II promoter, T7 RNA polymerase protects the -17 to -4 region from MPE-Fe(II) cleavage; when GTP is present, protection extends from -17 to +5 (noncoding strand). For a class III promoter, protection extends from -20 to -4 and in the presence of GTP from -20 to +5 (noncoding strand). The protected regions for the coding strands of both promoters were nearly identical with that seen for the noncoding strands. The binding constant for the class III promoter is (4 +/- 1.5) X 10(7) M-1 and in the presence of GTP increases to (10 +/- 1.7) X 10(7) M-1. These binding constants are about 1000 and 200 times greater, respectively, than values reported previously [Ikeda, R. A., & Richardson, C. C. (1986) Proc. Natl. Acad. Sci. U.S.A. 83, 3614-3618]. The differences in binding constants are probably due to tRNA and high salt used in those earlier experiments. Both tRNA and high salt (greater than 50 mM NaCl and greater than 10 mM MgCl2) inhibit the binding of the polymerase to the promoter. Optimal binding conditions occur at 2-5 mM MgCl2 and 0-10 mM NaCl.(ABSTRACT TRUNCATED AT 250 WORDS)
Correction: Lipolysis-stimulated lipoprotein receptor overexpression is a novel predictor of poor clinical prognosis and a potential therapeutic target in gastric cancer (2021)

[This corrects the article DOI: 10.18632/oncotarget.25952.].
Conservative garbage collection for general memory allocators (2000)

This paper explains a technique that integrates conservative garbage collection on top of general memory allocators. This is possible by using two data structures named malloc-tables and jump-tables that are computed at garbage collection time to map pointers to beginning of objects and their sizes. This paper describes malloc-tables and jump-tables, an implementation of a malloc/jump-table based conservative garbage collector for Doug Lea's memory allocator, and experimental results that compare this implementation with Boehm-Demers-Weiser GC, a state-of-the-art conservative garbage collector.
Lack of association between level of Plasminogen Activator Inhibitor-1 and estimates of tumor angiogenesis in early breast cancer (2007)

Plasminogen Activator Inhibitor type-1 (PAI-1) is involved in tumor invasion and progression. High levels of PAI-1 are associated with poor prognosis in breast cancer, and PAI-1 has been shown to play a role in angiogenic processes. Since estimates of tumor angiogenesis may predict poor prognosis we studied the relationship between PAI-1 and estimates of angiogenesis in breast cancer. Tumor tissue specimens from 438 breast cancer patients were included. Median follow-up was 10.3 years. Protein levels of PAI-1 were measured using an ELISA. Angiogenesis scores were performed using a Chalkley grid. Median PAI-1 level was 0.70 ng/mg protein (range, 0 - 90 ng/mg protein) and median Chalkley count was 5.00 (range, 2.67 - 12.00). Chalkley counts were not correlated with PAI-1. In univariate analysis both increasing PAI-1 and increasing Chalkley counts evaluated as continuous parameters were significantly associated with poor disease-specific survival with RR 1.04 (95% CI 1.02 - 1.07) (p<0.0001) and RR 1.11 (95% CI 1.01 - 1.22) (p=0.04), respectively. High tertiles of PAI-1 were borderline significantly correlated with poor disease-specific survival (p=0.06), whereas high tertiles of Chalkley counts were significantly associated with poor disease-specific survival (p=0.004). Combining low/low versus high/high tertiles of Chalkley counts and PAI-1 showed actuarial 10-year survival rates of 82% versus 52% (p=0.004). High N-stage (p<0.0001), grade (p<0.0001) and increasing levels of PAI-1 (p=0.009) were independent markers of death from breast cancer. This study confirms high PAI-1 or high Chalkley counts as markers of poor prognosis in breast cancer patients, and suggests that the prognostic impact of PAI-1 is independent of its supposed involvement in tumor angiogenesis.
Assessment of vertebral fractures and edema of the thoracolumbar spine based on water‐fat and susceptibility‐weighted images derived from a single ultra‐short echo time scan (2021)

The proposed sUTE-Dixon-SWI methodology allows the removal of unwanted low-frequency phases and enables water-fat separation and SWI processing from a single complex UTE image. The methodology can be used for the simultaneous assessment of vertebral fractures and BME of the thoracolumbar spine.
Whole Genome Sequence of an UnusualBorrelia burgdorferiSensu Lato Isolate (2011)

Human Lyme disease is caused by a number of related Borrelia burgdorferi sensu lato species. We report here the complete genome sequence of Borrelia sp. isolate SV1 from Finland. This isolate is to date the closest known relative of B. burgdorferi sensu stricto, but it is sufficiently genetically distinct from that species that it and its close relatives warrant its candidacy for new-species status. We suggest that this isolate should be named "Borrelia finlandensis."
Protective efficacy of BCG Pasteur. (2020)

&lt;p&gt;Mice were immunized sub-cutaneously with 1x10&lt;sup&gt;6&lt;/sup&gt; CFU BCG Pasteur and challenged with 100 CFU Mtb H37Rv via aerosol after 2 months. Bacterial burden in the lung was measured by CFU assay at days 10, 42, and 100 following aerosol challenge (n = 4–5 mice per group). Statistical significance was determined by Student’s &lt;i&gt;t&lt;/i&gt;-test.&lt;/p&gt; &lt;p&gt;(PDF)&lt;/p&gt;
Communication. Use of poly(L-lysine) and ascorbic acid for surface enhanced resonance Raman scattering analysis of acidic monoazo dyes (1993)

A surface enhanced resonance Raman scattering (SERRS) procedure is described for the analysis of acidic monoazo dyes. The SERRS spectra of these compounds can be obtained if a 0.01% solution of poly(L-lysine) is added to a citrate-reduced silver sol. Further enhancement of the SERRS intensities can be obtained by the addition of ascorbic acid. The discrimination between dyes offered by this procedure is demonstrated and a mechanism is proposed for the interaction between the poly(L-lysine), ascorbic acid and a dye.
Reduction‐Triggered Doxorubicin Delivery by Self‐Assembled Nanospheres of Lipoylated Caffeine (2020)

This study reports a new amphiphilic bioconjugate (CAFF-LA) derived from the lipoylation of a hydroxyethyl derivative of caffeine. In water, CAFF-LA self-assembles into nanospheres with an average size of 155 nm, as evidenced from dynamic light scattering and electron microscopy studies. The nanospheres are stable in serum and could be disintegrated upon exposure to the reducing environment of dithiothreitol (DTT; 10 mM) and glutathione (GSH; 10 mM). These nanospheres easily encapsulate the chemotherapy medication, doxorubicin (DOX), and demonstrate an efficacious transport into doxorubicin-resistant cervical cancer (HeLa) cells, wherein a marked induction in apoptosis and significantly lower IC<sub>50</sub> have been observed when compared to that of free drug. The in vitro assessment of cell viability and hemocompatibility present these nanospheres as potentially safe and efficient intracellular reduction stimulus-responsive drug-delivery vehicles.
Kinetic Modeling of Copper Biosorption by Immobilized Biomass (1998)

The kinetic modeling of copper biosorption by Arthrobacter sp. immobilized in a hydroxyethyl methacrylate-based matrix is reported in this work. The resin−biomass complex (RBC) has been used for copper biosorption in different conditions according to a factorial experiment. Factors investigated were cross-linker (trimethylolpropane trimethacrylate) concentration, biomass concentration in the solid, and particles' granulometry. A maximum copper specific uptake of about 7 mg of Cu/g of biomass (dry weight) has been observed, in the case of a RBC with the following characteristics: 2% (w/w) cross-linker concentration, 8% (w/w) biomass concentration, and 425−750 μm granulometry. The shrinking core model has been used for the fitting of experimental data. A good fit has been found in the case of controlling intraparticle diffusion in all experimental trials. The copper diffusion coefficient in RBC has been estimated from the slope of the regression lines. Values obtained for the diffusion coefficients do not differ from one another with respect to the estimated standard error. An average apparent copper diffusion coefficient of about 3 × 10-6 cm2 /s has been found.
Interaction between dyes and polyelectrolytes. XIII. Effect of dye aggregation on the excitation energy transfer between bound dyes (1982)

Abstract Effect of polyanions on the aggregation of methylene blue (MB) was investigated spectrophotometrically. The following polyanions were used: potassium poly(vinyl sulfate), potassium poly(styrenesulfonate), sodium poly(methacrylate), and sodium poly(acrylate). The state of aggregation was largely dependent on the kind of polyanion and polyanion‐MB ratio. MB‐photo‐sensitized isomerization of cis‐p ‐(phenylazo)phenyltrimethylammonium iodide( cis ‐PTA) to the transisomer was used advantageously to investigate the effect of dye aggregation on the triplet excitation energy transfer between cationic dyes bound to polyanions. Although the efficiency of the excitation energy transfer between MB and cis ‐PTA was enhanced by the addition of polyanions, the formation of highly aggregated MB reduced the efficiency of the excitation energy transfer. Correlation with the dye aggregation induced by polyanions and the efficiency of excitation energy transfer between dyes was discussed.
Corrosion Resistance and Mechanical Properties of Alloy 803 for Heat Resisting Applications (1997)

Abstract Alloy 803 was developed for applications as straight and twisted ID finned tubing in the petrochemical and chemical process industries, such as ethylene pyrolysis, that require enhanced resistance to oxidation and carburization in addition to adequate stress rupture strength. This paper presents the mechanical properties characterized for the alloy produced in other forms, such as plate, sheet and bar products, for applications in the heat treatment, chemical and petrochemical industries. The mechanical properties covered include room and high temperature tensile test results, impact strength, creep and stress rupture data for temperatures up to 2000°F (1093°C) at various stress levels. The preliminary results of the room and high temperature tensile and impact properties after long term exposures at intermediate temperatures are also presented. In addition to mechanical properties, the corrosion performance of alloy 803 in oxidation, sulfidation and carburization environments are presented.
Primary Cerebral Lymphoma and Glioblastoma Multiforme: Differences in Diffusion Characteristics Evaluated with Diffusion Tensor Imaging (2007)

The FA and ADC of primary cerebral lymphoma were significantly lower than those of GBM. DTI is able to differentiate lymphomas from GBM.
Diacetonitrile[N,N′-bis(2,6-diisopropylphenyl)ethane-1,2-diimine]dichloridochromium(II) acetonitrile solvate (2009)

The title compound, [CrCl(2)(CH(3)CN)(2)(C(26)H(36)N(2))]·CH(3)CN, was synthesized by the reaction of CrCl(2)(THF)(2) with N,N'-bis-(2,6-diisopropyl-phen-yl)ethane-1,2-diimine in dichloro-methane/acetonitrile. The chromium center is coordinated by two N atoms of the chelating diimine ligand, two chloride ions in a trans configuration with respect to each other, and by two N atoms of two acetonitrile mol-ecules in a distorted octa-hedral geometry.
Impact of Blood Vessel Quantity and Vascular Expression of CD133 and ICAM-1 on Survival of Glioblastoma Patients (2017)

Glioblastoma (GB) is the most angiogenic tumor. Nevertheless, antiangiogenic therapy has not shown significant clinical efficacy. The aim of this study was to assess blood vessel characteristics on survival of GB patients. Surgically excised GB tissues were histologically examined for overall proportion of glomeruloid microvascular proliferation (MP) and the total number of blood vessels. Also, immunohistochemical vascular staining intensities of CD133 and ICAM-1 were determined. Vessel parameters were correlated with patients' overall survival. The survival time depended on the number of blood vessels (<i>p</i> = 0.03) but not on the proportion of MP. Median survival times for patients with low (<median) and high (≥median) number of blood vessels were 9.0 months (95% CI: 7.5-10.5) and 12.0 months (95% CI: 9.3-14.7). Also, median survival times for patients with low (<median) and high (≥median) vascular expression level of CD133 were 9.0 months (95% CI: 8.0-10.1) and 12.0 months (95% CI: 10.3-13.7). In contrast, the staining intensity of vascular ICAM-1 did not affect survival. In multivariate analysis, the number of blood vessels emerged as an independent predictor for longer overall survival (HR: 2.4, 95% CI: 1.2-5.0, <i>p</i> = 0.02). For success in antiangiogenic therapy, better understanding about tumor vasculature biology is needed.
A generic architecture for multi-modulus dividers in low-power and high-speed frequency synthesis (2005)

The paper presents a generic architecture for programmable multi-modulus dividers (MMD) for low-power and high-speed frequency synthesis applications. The proposed architecture uses cascaded divide by 2/3 cells in a ripple fashion except for the last cell, which is a P/(P+1) dual modulus prescaler used to adjust the minimum division ratio and the required division range. This approach provides an optimized architecture with minimum current consumption, the smallest area and minimum number of control bits for designing MMDs with a unit step increment.
Development and Assessment of a Video-Based Intervention to Improve Rhinoplasty Informed Consent (2021)

There has been a growing interest in improving the informed consent process to ensure patients truly understand the benefits, risks, and alternatives of their procedures. Herein, we sought to describe the production of an educational video to supplement the traditional rhinoplasty informed consent process. Additionally, we evaluate satisfaction and risk recall among prospective rhinoplasty patients who participated in the video-assisted informed consent process. One author attended 30 rhinoplasty consultations where informed consent was performed and generated 65 questions related to the benefits, risks, alternatives, and general knowledge of rhinoplasty operations. A video of the senior author answering these questions was filmed and edited to 25 minutes. Prospective rhinoplasty patients watched the video before their initial consultation and were asked to complete two surveys assessing their satisfaction with the video-assisted process as well as their ability to recall risks discussed in the video. Understandability and actionability of the video was assessed by three independent reviewers using the Patient Education Materials Assessment Tool. Postvideo surveys were completed by 40 patients. Patients strongly agreed that the video informed them about rhinoplasty risks and benefits (4.90/5.00), effectively answered their questions and/or concerns (4.78/5.00), and provided adequate information before surgery (4.85/5.00). Participants strongly recommended that all prospective patients watch the video prior to surgery (4.97/5.00). Participants on average correctly answered 4.00 ± 0.877 out of five risk recall questions. There was no statistically significant difference in risk recall performance between college graduates (4.19 ± 0.602) and those who did not graduate college (3.79 ± 1.08), <i>p</i> = 0.076. No significant correlation was found between patient age and recall performance (<i>r</i> = -0.011), <i>p</i> = 0.943. The overall mean understandability and actionability scores for the video were 100%. Video-assisted informed consent for rhinoplasty may enhance and overcome limitations to the traditional verbal consent process by ensuring comprehensive, standardized, and readily understandable information.
Sex-Steroid Levels in Obese Men with Prostate Cancer (2007)

With the rising prevalence of obesity in the U.S. and compelling data that suggest an association between obesity and prostate cancer mortality,
Opponent modelling and commercial games (2013)

Abstract- To play a game well a player needs to understand the game. To defeat an opponent, it may be sufficient to understand the opponent’s weak spots and to be able to exploit them. In human practice, both elements (knowing the game and knowing the opponent) play an important role. This article focuses on opponent modelling independent of any game. So, the domain of interest is a collection of two-person games, multiperson games, and commercial games. The emphasis is on types and roles of opponent models, such as speculation, tutoring, training, and mimicking characters. Various implementations are given. Suggestions for learning the opponent models are described and their realization is illustrated by opponent models in game-tree search. We then transfer these techniques to commercial games. Here it is crucial for a successful opponent model that the changes of the opponent’s reactions over time are adequately dealt with. This is done by dynamic scripting, an improvised online learning technique for games. Our conclusions are (1) that opponent modelling has a wealth of techniques that are waiting for implementation in actual commercial games, but (2) that the games’ publishers are reluctant to incorporate these techniques since they have no definitive opinion on the successes of a program that is outclassing human beings in strength and creativity, and (3) that game AI has an entertainment factor that is too multifaceted to grasp in reasonable time. 1