gebhart/patrepeval huggingface dataset:
MP10-06 OBESITY AND OUTCOMES OF ROBOTIC ASSISTED SACROCOLPOPEXY (2016)

You have accessJournal of UrologyUrodynamics/Lower Urinary Tract Dysfunction/Female Pelvic Medicine: Pelvic Prolapse1 Apr 2016MP10-06 OBESITY AND OUTCOMES OF ROBOTIC ASSISTED SACROCOLPOPEXY Lindsay Martin, Rose Calixte, Bogdan Grigorescu, and Peter Finamore Lindsay MartinLindsay Martin More articles by this author , Rose CalixteRose Calixte More articles by this author , Bogdan GrigorescuBogdan Grigorescu More articles by this author , and Peter FinamorePeter Finamore More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.2336AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES We sought to compare operative time in obese versus non-obese women undergoing robotic assisted sacrocolpopexy (RASC). Secondary objectives were to compare peri-operative complications and reoperations. We hypothesized that obese patients would have longer operative times. METHODS We performed a retrospective chart review of women who underwent RASC by a single surgeon at our institution from August 2009 to 2013. BMI was categorized into three classes (Normal: BMI < 25 kg/m2, Overweight: 25 kg/m2 = BMI = 30 kg/m2, and Obese: BMI > 30 kg/m2). Operative time was defined as skin incision to skin closure. Comparisons between patient groups were made using one-way analysis of variance, the Kruskal-Wallis test, and exact Pearson’s chi-square test. Results were considered significant when p-value < 0.05. All analyses were done using SAS 9.4®. RESULTS Our study included 61, 72 and 46 patients classified as healthy-weight, overweight, and obese, respectively. Healthy-weight patients were significantly older, more parous, and more frequently post-menopausal. Overweight patients more frequently underwent concomitant salpingoophorectomy (p = 0.019). No other concomitant procedure met threshold for significance. Mean operative time was 213, 213 and 217 minutes in the healthy-weight, overweight and obese groups, respectively. There was no difference in operative time among the three groups (p-value = 0.385). Specifically, there was no difference in operative time between overweight versus obese, and healthy-weight versus obese patients. Additionally, intraoperative complications, length of hospital stay, return to the operating room (OR) and estimated blood loss were not different among the three groups. CONCLUSIONS Operative times and perioperative complication rates of RASC are similar in obese and non-obese patients. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e104 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Lindsay Martin More articles by this author Rose Calixte More articles by this author Bogdan Grigorescu More articles by this author Peter Finamore More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...
Application of Classical Resolution for Separation of DL‐Serine (2010)

Abstract For resolution of chiral compound‐forming substances diastereomeric salt formation is the most important classical separation technique. Diastereomeric salts possess different physical and chemical properties, e.g., solubilities, which facilitate the effective separation via crystallization. A maximum recovery of both diastereomeric salts is usually unachievable when there is a lack of quantitative information regarding solubility and metastable zone width. The present work provides experimental results for the formation of diastereomeric salts of DL ‐serine. As basic thermodynamic data binary melting and ternary solubility phase diagrams are shown and discussed. A plan for a series of crystallization processes is suggested for the recovery of both salts in pure form with a maximum possible yield.
Setting the Biological Scene (2004)

This chapter contains sections titled Introducing Biological Sequence Analysis Protein and Polypeptides Generalised Models and their Use The Central Dogma of Molecular Biology Genome Sequencing The Example DNA-gene-protein system we will use Where to from Here
Interface control of electronic and optical properties in IV–VI and II–VI core/shell colloidal quantum dots: a review (2016)

Semiconductor colloidal quantum dots (CQDs) have attracted vast scientific and technological interest throughout the past three decades, due to the unique tuneability of their optoelectronic properties by variation of size and composition. However, the nanoscale size brings about a large surface-to-bulk volume ratio, where exterior surfaces have a pronounced influence on the chemical stability and on the physical properties of the semiconductor. Therefore, numerous approaches have been developed to gain efficient surface passivation, including a coverage by organic or inorganic molecular surfactants as well as the formation of core/shell heterostructures (a semiconductor core epitaxially covered by another semiconductor shell). This review focuses on special designs of core/shell heterostructures from the IV-VI and II-VI semiconductor compounds, and on synthetic approaches and characterization of the optical properties. Experimental observations revealed the formation of core/shell structures with type-I or quasi-type-II band alignment between the core and shell constituents. Theoretical calculations of the electronic band structures, which were also confirmed by experimental work, exposed surplus electronic tuning (beyond the radial diameter) with adaptation of the composition and control of the interface properties. The studies also considered strain effects that are created between two different semiconductors. It was disclosed experimentally and theoretically that the strain can be released via the formation of alloys at the core-shell interface. Overall, the core/shell and core/alloyed-shell heterostructures showed enhancement in luminescence quantum efficiency with respect to that of pure cores, extended lifetime, uniformity in size and in many cases good chemical sustainability under ambient conditions.
Novel chenodeoxycholic acid–sodium alginate matrix in the microencapsulation of the potential antidiabetic drug, probucol. Anin vitrostudy (2015)

Context: We previously designed, developed and characterized a novel microencapsulated formulation as a platform for the targeted delivery of Probucol (PB) in an animal model of Type 2 Diabetes. Objective: The objective of this study is to optimize this platform by incorporating Chenodeoxycholic acid (CDCA), a bile acid with good permeation-enhancing properties, and examine its effect in vitro. Using sodium alginate (SA), we prepared PB-SA (control) and PB-CDCA-SA (test) microcapsules. Results and discussion: CDCA resulted in better structural and surface characteristics, uniform morphology, and stable chemical and thermal profiles, while size and rheological parameters remained unchanged. PB-CDCA-SA microcapsules showed good excipients’ compatibilities, as evidenced by differential scanning calorimetry (DSC), Fourier transform infrared spectroscopy, scanning electron microscopy and energy dispersive X-ray spectroscopy studies. CDCA reduced microcapsule swelling at pH 7.8 at both 37 °C and 25 °C and improved PB-release. Conclusion: CDCA improved the characteristics and release properties of PB-microcapsules and may have potential in the targeted oral delivery of PB.
Systems Level Understanding of Interconnected Methane and Nitrogen Cycles Using Complex Synthetic Communities (2020)

The main goal of this project was to follow up on prior discovery of the communal nature of methane utilization by the aerobic methanotrophic bacteria, resulting in carbon transfer along a food chain. This goal was approached via manipulation of specially designed, synthetic bacterial communities, fed exclusively by methane, under a variety of simulated environmental conditions. Using (meta)genomics, metatranscriptomics, stable isotope probing and mutant generation, we obtained solid evidence for the nature of the core microbiota involved in collaborative methane consumption, the major players (true methanotrophs) being the members of the family Methylococcaceae, their major partners (non-methanotrophic methylotrophs) being members of the family Methylophilaceae, and minor but persistent partners in the communities being members of the orders Burkholderiales and Bacteroidetes. Metabolic reconstruction from single genomes and metagenome-assembled genomes (MAGs), along with metatranscriptomics results delineated major pathways for carbon metabolism, suggesting that the methanotrophs share different organic compounds with different functional guilds: methanol with Methylophilaceae, acetate with Burkholderiales, and polymeric substances with Bacteroidetes. Overall, the results of this project expand our understanding of microbial metabolism of methane and, thus, provide basis for strategies for microbial methane mitigation, with obvious benefits to the society of the United States and worldwide.
Chemical composition, toxicity and larvicidal and antifungal activities of Persea americana (avocado) seed extracts (2009)

The present study had the aim of testing the hexane and methanol extracts of avocado seeds, in order to determine their toxicity towards Artemia salina, evaluate their larvicidal activity towards Aedes aegypti and investigate their in vitro antifungal potential against strains of Candida spp, Cryptococcus neoformans and Malassezia pachydermatis through the microdilution technique. In toxicity tests on Artemia salina, the hexane and methanol extracts from avocado seeds showed LC50 values of 2.37 and 24.13 mg mL-1 respectively. Against Aedes aegypti larvae, the LC50 results obtained were 16.7 mg mL-1 for hexane extract and 8.87 mg mL-1 for methanol extract from avocado seeds. The extracts tested were also active against all the yeast strains tested in vitro, with differing results such that the minimum inhibitory concentration of the hexane extract ranged from 0.625 to 1.25mg L-(1), from 0.312 to 0.625 mg mL-1 and from 0.031 to 0.625 mg mL-1, for the strains of Candida spp, Cryptococcus neoformans and Malassezia pachydermatis, respectively. The minimal inhibitory concentration for the methanol extract ranged from 0.125 to 0.625 mg mL-1, from 0.08 to 0.156 mg mL-1 and from 0.312 to 0.625 mg mL-1, for the strains of Candida spp., Cryptococcus neoformans and Malassezia pachydermatis, respectively.
The Compound Multiple Access Channel With Partially Cooperating Encoders (2011)

The goal of this paper is to provide a rigorous information-theoretic analysis of subnetworks of interference networks. We prove two coding theorems for the compound multiple-access channel (MAC) with an arbitrary number of channel states. The channel state information at the transmitters is such that each transmitter has a finite partition of the set of states and knows which element of the partition the actual state belongs to. The receiver may have arbitrary channel state information. The first coding theorem is for the case that both transmitters have a common message and that each has an additional private message. The second coding theorem is for the case where rate-constrained, but noiseless transmitter cooperation is possible. This cooperation may be used to exchange information about channel state information as well as the messages to be transmitted. The cooperation protocol used here generalizes Willems' conferencing. We show how this models base station cooperation in modern wireless cellular networks used for interference coordination and capacity enhancement. In particular, the coding theorem for the cooperative case shows how much cooperation is necessary in order to achieve maximal capacity in the network considered.
Performance-power optimization of memory components for complex embedded systems (2002)

Optimizing performance and power during the design of embedded systems for real-time constrained applications is an important problem. This paper presents a network flow optimization technique to analyze power and performance tradeoffs for memory component design of an embedded system. The optimal number of external and internal memory accesses, memory sizes, and the number of extra computations (or data regeneration) for a number of tasks is determined. This is unlike previous research, which has only discussed ad hoc suggestions for this problem. The network flow approach can be solved to a globally optimal solution in polynomial time using very fast and efficient algorithms. Results for a large, complex, real industrial application-audio compression-show that this network flow technique provides up to 3.11 and 1.44 times improvement in power and performance respectively. This research is important for industry since power, performance and cost considerations at the early stages of design are crucial for mapping high-performance applications into cost-efficient and reliable systems.
Reactivities of Inositol and Ribonucleoside Phosphodiesters toward P−O Bond Cleavage (2001)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTReactivities of Inositol and Ribonucleoside Phosphodiesters toward P−O Bond CleavageRobert J. Kubiak and Karol S. BruzikView Author Information Department of Medicinal Chemistry and Pharmacognosy University of Illinois at Chicago, Chicago, Illinois 60612 Cite this: J. Am. Chem. Soc. 2001, 123, 8, 1760–1761Publication Date (Web):January 31, 2001Publication History Received16 October 2000Published online31 January 2001Published inissue 1 February 2001https://pubs.acs.org/doi/10.1021/ja003675ahttps://doi.org/10.1021/ja003675arapid-communicationACS PublicationsCopyright © 2001 American Chemical SocietyRequest reuse permissionsArticle Views255Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Bond cleavage,Cyclization,Monomers,Peptides and proteins,Phosphates Get e-Alerts
Corrigendum: An Autism-Associated de novo Mutation in GluN2B Destabilizes Growing Dendrites by Promoting Retraction and Pruning (2022)

[This corrects the article DOI: 10.3389/fncel.2021.692232.].
Induction of programmed cell death (apoptosis) by dengue virus in vitro and in vivo. (1998)

Dengue is a human disease which may be fatal in its hemorrhagic form. How dengue virus- and host-specified factors underlie virulence and pathogenesis is poorly understood. An immunological disorder is thought to be involved in dengue physiological symptoms. Whether the immune response is deleterious or beneficial to the host remains a matter of debate. In this review, we summarized developments in research on viral pathogenesis in the context of apoptosis triggered by dengue virus infection. Apoptosis, an active process of cell destruction, is one of the important consequences of dengue virus infection in vitro and in vivo. Dengue virus replication induces apoptosis in mouse neurons and human hepatocytes. The ability to activate this genetically programmed cell death pathway is dependent on both viral and cellular determinants.
Near-field electromagnetic tomography applied to current density reconstruction in metallized capacitors (2005)

A nonintrusive method of current cartography inside a component is presented. The measurement of the current density in metallized film capacitors has numerous applications, including nondestructive testing, new component design, and validation of existing models on current distribution in capacitors. The method is based upon the measurement of the magnetic field created by a capacitor and the current density reconstruction by means of inverse problem methodology. The experimental setup comprises of a radio-frequency generator operating between 10 to 1000 MHz, a near-field probe, an XY positioning table and a computer used for control and data acquisition. The first results confirm that, near some frequencies, the current density in the capacitor becomes nonhomogeneous and increases dramatically in some areas.
Functional characterization, localization, and molecular identification of rabbit intestinal N-amino acid transporter (2008)

We have characterized the Na-glutamine cotransporter in the rabbit intestinal crypt cell brush border membrane vesicles (BBMV). Substrate specificity experiments showed that crypt cell glutamine uptake is mediated by system N. Real-time PCR experiments showed that SN2 (SLC38A5) mRNA is more abundant in crypt cells compared with SN1 (SLC38A3), indicating that SN2 is the major glutamine transporter present in the apical membrane of the crypt cells. SN2 cDNA was obtained by screening a rabbit intestinal cDNA library with human SN1 used as probe. Rabbit SN2 cDNA encompassed a 473-amino-acid-long open reading frame. SN2 protein displayed 87% identity and 91% similarity to human SN2. Functional characterization studies of rabbit SN2 were performed by using vaccinia virus-mediated transient expression system. Substrate specificity of the cloned transporter was identical to that of SN2 described in the literature and matched well with substrate specificity experiments performed using crypt cell BBMV. Cloned rabbit SN2, analogous to its human counterpart, is Li(+) tolerant. Hill coefficient for Li(+) activation of rabbit SN2-mediated uptake was 1. Taken together, functional data from the crypt cell BBMV and the cloned SN2 cDNA indicate that the crypt cell glutamine transport is most likely mediated by SN2.
Physiological assays of suprathreshold hearing are consistent with widespread deafferentation of the human auditory periphery (2019)

Multiple animal models have robustly shown the effects of noise-exposure and aging can have on the afferent synapses between the cochlea and the auditory nerve. This cochlear synaptopathy can affect responses to suprathreshold stimuli while leaving audiometric thresholds intact. However, currently, there is much debate on whether these same changes occur in humans with significant noise-exposure or with middle age. Our study examined two different physiological responses in which these afferent synapses are a crucial component, the auditory brainstem response (ABR) and the middle ear muscle reflex (MEMR). Versions of these measures were completed in both a clinical setting and a laboratory. Responses to both measures in both testing environments demonstrated significant age and noise-exposure effects. Moreover, these effects remained significant even after statistically accounting for variability in audiometric sensitivity and otoacoustic emissions, suggesting that despite clinically normal audiograms, cochlear synaptopathy may be a widespread occurrence in humans with both acoustic-overexposure and normal aging. Finally, our results suggest that a battery combining ABR and MEMR measures may be viable as a non-invasive assay of synaptopathy and can help examine the perceptual sequelae of such damage.
Applicability of Abstraction and Control of Traffic Engineered Networks (ACTN) to Enhanced VPN (2018)

The Abstraction and Control of Traffic Engineered Networks (ACTN)
defines an SDN-based architecture that relies on the concepts of
network and service abstraction to detach network and service control
from the underlying data plane. This document outlines the overview
of ACTN capability and the applicability of ACTN to Enhanced VPN. In
particular, this document also discusses how ACTN features can fulfill
some of the requirements of the enhanced VPN, which is also known as
VPN+ [VPN+].
Serial Decoders-Based Auto-Encoders for Image Reconstruction (2022)

Auto-encoders are composed of coding and decoding units; hence, they hold an inherent potential of being used for high-performance data compression and signal-compressed sensing. The main disadvantages of current auto-encoders comprise the following aspects: the research objective is not to achieve lossless data reconstruction but efficient feature representation; the evaluation of data recovery performance is neglected; it is difficult to achieve lossless data reconstruction using pure auto-encoders, even with pure deep learning. This paper aims at performing image reconstruction using auto-encoders, employs cascade decoders-based auto-encoders, perfects the performance of image reconstruction, approaches gradually lossless image recovery, and provides a solid theoretical and applicational basis for auto-encoders-based image compression and compressed sensing. The proposed serial decoders-based auto-encoders include the architectures of multi-level decoders and their related progressive optimization sub-problems. The cascade decoders consist of general decoders, residual decoders, adversarial decoders, and their combinations. The effectiveness of residual cascade decoders for image reconstruction is proven in mathematics. Progressive training can efficiently enhance the quality, stability, and variation of image reconstruction. It has been shown by the experimental results that the proposed auto-encoders outperform classical auto-encoders in the performance of image reconstruction.
A new methodology for evaluating profile and position errors of blade based on parameter priority (2020)

As one of the core components of a turbine, the quality of the blade manufacturing has a strong impact on the energy conversion efficiency of the turbine, where the key technology of quality evaluation of blades is point cloud registration. However, with the application of structured light three-dimensional measurement technology in full profile measurement, the typical point cloud registration methods only focus on the minimization of surface profile error, ignoring the position error relative to reference datum, which can easily lead to the misjudgment of qualified blades. In this paper, a new blade error evaluation method is presented to register the point cloud data scanned from a physical blade to its theoretical CAD model, which fits the two surfaces based on parameter priority. Firstly, qualified blades are quickly selected after global fine registration using the best-fit algorithm. Subsequently, based on the priority of position error parameters, the coordinate descent algorithm combined with the minimum zone criterion is adopted for local fine registration, which guarantees accurate evaluation results. Finally, the shape and position error of the actual blade is obtained accurately by calculating transformation parameters of registration and the deviation between the registered point cloud and its CAD model of the blade. Experimental results show that compared with state-of-the-art registration methods, the presented method gives higher priority to the parameters which are difficult to finish or repair by machining, and the position errors are controlled in the tolerance area, which effectively reduces the misjudgment. In addition, evaluation results of blade errors with the method are mainly reflected in profile, which is valuable for guiding the blade finishing or trimming in practice.