gebhart/patrepeval huggingface dataset:
Serum Myoglobin/Carbonic Anhydrase III Ratio in the Diagnosis of Perioperative Myocardial Infarction During Coronary Bypass Surgery (2003)

Objective- The purpose of the present study was to evaluate the usefulness of the myoglobin/carboanhydrase III (Myo/CAIII) ratio in the diagnosis of peri operative myocardial infarction during coronary artery bypass surgery.Design- Thirty patients undergoing elective coronary artery bypass grafting (CABG) were included in the series. The patients were randomized in two groups: One received conventional normothermic retrograde blood cardioplegia, while the other was subjected to a 5-min period of ischemic preconditioning before cardioplegia. Biochemical markers for myocardial and skeletal muscle injury were measured in serial blood samples taken postoperatively from 4 h after aortic declamp.Results- Three patients were diagnosed to have suffered from peri operative myocardial infarction on the basis of significant elevations of troponin T and creatine kinase MB-isoenzyme (CK-MB) concentrations. In these particular patients the Myo/CAIII ratio Increased rapidly after aortic declamping. In uncomplicated patients, the median value of the Myo/CAIII ratio remained within normal limits. There was a Positive correlation between the net output of lactate during the aortic cross-clamping period and post-perative Myo/CAIII ratio. The Myo/CAIII ratio proved to be a more specific indicator for myocardial damage than myoglobin alone. The Myo/CAIII ratio was higher in the preconditioning group than in the Control group.Conclusion- Myo/CAIII ratio is a sensitive and specific marker for perioperative myocardial infarction Increasing rapidly after aortic declamping. This ratio could also be used when assessing the extent of ischemic myocardial injury and comparing different Surgical and cardioprotective techniques.
Statistical Information Based Single Neuron Adaptive Control for Non-Gaussian Stochastic Systems (2012)

Based on information theory, the single neuron adaptive control problem for stochastic systems with non-Gaussian noises is investigated in this paper. Here, the statistic information of the output within a receding window rather than the output value is used for the tracking problem. Firstly, the single neuron controller structure, which has the ability of self-learning and self-adaptation, is established. Then, an improved performance criterion is given to train the weights of the single neuron. Furthermore, the mean-square convergent condition of the proposed control algorithm is formulated. Finally, comparative simulation results are presented to show that the proposed algorithm is superior to the PID controller. The contributions of this work are twofold: (1) the optimal control algorithm is formulated in the data-driven framework, which needn’t the precise system model that is usually difficult to obtain; (2) the control problem of non-Gaussian systems can be effectively dealt with by the simple single neuron controller under improved minimum entropy criterion.
Skeletonized inversion of surface wave: Active source versus controlled noise comparison (2016)

Abstract We have developed a skeletonized inversion method that inverts the S-wave velocity distribution from surface-wave dispersion curves. Instead of attempting to fit every wiggle in the surface waves with predicted data, it only inverts the picked dispersion curve, thereby mitigating the problem of getting stuck in a local minimum. We have applied this method to a synthetic model and seismic field data from Qademah fault, located at the western side of Saudi Arabia. For comparison, we have performed dispersion analysis for an active and controlled noise source seismic data that had some receivers in common with the passive array. The active and passive data show good agreement in the dispersive characteristics. Our results demonstrated that skeletonized inversion can obtain reliable 1D and 2D S-wave velocity models for our geologic setting. A limitation is that we need to build layered initial model to calculate the Jacobian matrix, which is time consuming.
Mitigating Circulating Common-Mode Currents Between Parallel Soft-Switched Drive Systems (2007)

A mathematical model that Is developed for a generalized drive system, including common-mode passive and active elements, is used to explore the issues of paralleling soft-switched resonant dc-link drive systems. Differences between the modulation pattern for each drive system cause common voltage disturbances, which lead to significant circulating currents between the drive systems. Control methods for actively compensating for common-mode circulating currents or reducing the common- mode voltage disturbances are investigated. Practical modifications to the drive system controls are implemented to reduce the circulating currents between paralleled systems.
Corneal and Conjunctival Changes in Congenital Erythropoietic Porphyria (1989)

Penetrating keratoplasty and conjunctival resection were performed on a 53-year-old woman with confirmed congenital erythropoietic porphyria. Corneal and conjunctival tissue samples, studied by light and electron microscopy, revealed inflammatory cells and a reduced keratocyte population. Vessels within the conjunctival and corneal stroma displayed a thickened basement membrane. Microfibrillar material was seen in the extracellular spaces of the conjunctival stroma. These changes are similar to those reported for ultraviolet light-exposed skin of porphyria patients. The Descemet's membrane lacked the normal fetal and postnatal banding. It presented as a homogeneous layer, consisting of uniform, densely packed collagen fibers, which suggests endothelial damage in utero. The corneal endothelium was severely damaged.
Synthesis and study of transport and magnetic properties of magnesium cage compounds $R$Ni$_{2}$Mg$_{20}$ ($R$ = Pr and Nd) (2021)

We have synthesized magnesium cage compounds $R$Ni$_{2}$Mg$_{20}$ ($R$ = Pr and Nd). We report the measurements of electrical resistivity $ρ$, magnetic susceptibility $χ$, isothermal magnetization $M$, and specific heat $C$. Polycrystalline samples with $R$ = Pr and Nd were obtained by annealing, while the counterparts for $R$ = La, Ce, and Y were found to be absent. The $ρ(T)$ data for $R$ = Pr and Nd monotonically decrease on cooling from 300 K to 40 K and exhibit shoulders at around 13 K and 15 K, respectively. The Curie-Weiss behaviors of the $χ(T)$ data indicate the trivalent states of both the Pr and Nd ions. For $R$ = Pr, the maximum in $C(T)$ at around 7 K is reproduced by a doublet-triplet two-level model with an energy gap of 14 K. The peak in $C(T)$ at 0.7 K is attributed to a short-range order of quadrupolar degrees of freedom in the non-Kramers ground doublet. On the other hand, for $R$ = Nd, a maximum in $C(T)$ at around 9 K is explained by thermal excitation from a ground state doublet to an excited quartet separated by 23 K. Upon further cooling, $C(T)$ shows a lambda-shaped peak at 1.5 K. By applying magnetic fields up to 2 T, the peak becomes broad and shifts to higher temperatures, which is a characteristic of a ferromagnetic order.
A new method for 2D-vector blood flow imaging based on unconventional beamforming techniques (2014)

Conventional Ultrasound (US) Doppler methods for blood flow imaging are limited to velocity estimations only in the axial direction, i.e. along the beam direction. Transverse oscillations (TO) methods extend blood investigations towards multidimensional estimates, and detailed descriptions of complex and fast blood flows are achievable by high frame-rate (HFR) imaging methods. In this work, TO are coupled with plane-waves (PWs) to reconstruct radio-frequency (RF) images with bi-directional oscillations in the pulse-echo field. The achieved RF images are exploited by a 2D phase-based displacement estimator to produce 2D-vector flow maps. A preliminary simulation study confirmed the capability of the method to produce the designed oscillations in the RF pulse-echo fields as well as the possibility to obtain 2D-vector maps with errors lower than 10% in many different conditions.
Optimization of generalized LT codes for progressive image transfer (2012)

Rateless codes allow a user to incrementally send additional redundancy, so they can be useful for heterogeneous and time-varying networks for which the choice of redundancy level in advance is difficult. Rateless codes are an attractive application layer forward error correction solution due to their flexibility and capacity-approaching performance. The original rateless codes were developed for the delivery of equally important information. In many multimedia applications, some data symbols are more important than others. Unequal error protection (UEP) designs are attractive solutions for such transmissions. However previous UEP rateless code designs were aimed for coarsely layered sources and might exhibit poor performance for fine-grained progressive coding. The main objective of this paper is to introduce a more generalized coding scheme, parameters of which can be tailored for progressive multimedia transmission. We present the optimization of a generalized rateless code using two different progressive source transmission protocols. Proposed coding scheme is shown to exhibit better unequal protection and recovery time properties than other published results.
Transforming growth factors released from Kirsten sarcoma virus transformed cells do not compete for epidermal growth factor membrane receptors (1983)

Kirsten murine sarcoma virus (KiMSV)-transformed rat kidney cells (KNRK) release small polypeptides (Mr 12,500-15,300) into the culture medium that are capable of stimulating normal rat kidney cells (NRK) to form colonies in soft agar. The transforming growth factors (TGFs) did not compete with epidermal growth factor (EGF) for its receptor and did not induce specific phosphorylation of EGF receptor on NRK cell membranes. These properties differ from the TGFs isolated by other investigators. Our data further establish the heterogeneity of the materials produced by transformed cells that induce transformation-specific changes in normal cells.
CMU sidewalk navigation system: a blackboard-based outdoor navigation system using sensor fusion with colored-range images (1986)

We describe the CMU Sidewalk Navigation System, which can drive a vehicle in the outdoor environment of the CMU campus. The system includes all modules necessary for outdoor navigation .. modules for route planning, local path planning, vehicle driving, perception, and map data. The perception module uses sensor fusion with color and rage data to analyze complex outdoor scenes accurately and efficiently. 2. System Architecture for the Outdoor Navigati0.n System
In-vitro characterisation of a novel antimicrobial agent, TNP-2092, against Helicobacter pylori clinical isolates (2018)

TNP-2092 is highly active against H. pylori and against strains resistant to clarithromycin or levofloxacin. Its antibacterial activity is both concentration- and time-dependent .The antibacterial activity of TNP-2092 appears to be pH-dependent and is more active under neutral pH. TNP-2092 represents a promising new therapy for the treatment of H. pylori infection in primary patients.
Roadmap to wide band optical GEO relay networks (2012)

Optical inter-satellite communication has been verified in-orbit. Between two LEO satellites bit error rates better than 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-11</sup> at a data rate of 5.625 Gbps are achieved. Optical LEO-to-ground and ground-to-LEO links have been demonstrated. For the first time ESA will apply optical communication for operational services. The LEO-to-GEO link of a GEO relay, EDRS, the European data relay system, shall be established by optical communication at a data rate of 1.8 Gbps with a bit error rate of 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-8</sup> . For the time being the GEO-to-ground link still is based on radio frequency communication limiting the overall GEO relay data rate to the value of about 2 Gbps. Significantly higher data rates will be achieved by optical space-to-ground links with ground stations equipped with adaptive optics as has been demonstrated in a free-field measurement campaign. Optical LEO-to-ground and GEO-to-ground links shall be verified in the near future. Optical Air-to-GEO links are under preparation.
Molecular basis of N-acetylglucosaminyltransferase I deficiency in Arabidopsis thaliana plants lacking complex N-glycans (2005)

GnTI (N-acetylglucosaminyltransferase I) is a Golgi-resident enzyme essential for the processing of high-mannose to hybrid and complex N-glycans. The Arabidopsis thaliana cgl mutant lacks GnTI activity and as a consequence accumulates oligomannosidic structures. Molecular cloning of cgl GnTI cDNA revealed a point mutation, which causes a critical amino acid substitution (Asp144-->Asn), thereby creating an additional N-glycosylation site. Heterologous expression of cgl GnTI in insect cells confirmed its lack of activity and the use of the N-glycosylation site. Remarkably, introduction of the Asp144-->Asn mutation into rabbit GnTI, which does not result in the formation of a new N-glycosylation site, led to a protein with strongly reduced, but still detectable enzymic activity. Expression of Asn144 rabbit GnTI in cgl plants could partially restore complex N-glycan formation. These results indicate that the complete deficiency of GnTI activity in cgl plants is mainly due to the additional N-glycan, which appears to interfere with the proper folding of the enzyme.
Syntheses, structures and properties of two zinc coordination polymers based on bis(triazole) and sulfoisophthalate (2014)

Two zinc(II) coordination polymers {[Zn(tmtz)(H2O)4][Zn2(tmtz)2(sip)2]·3H2O}n (1) and [Zn3(tmtz)2(sip)2(H2O)4]·2H2O}n (2) (tmtz = 1,4-bis(1,2,4-triazol-1-ylmethyl)-2,3,4,5-tetramethylbenzene, sip = 5-sulfoisophthalate) were synthesized and structurally characterized. X-ray structural analysis shows that 1 is comprised of two distinct and crystallographically independent polymeric motifs polythreading together. The first motif of 1 is the (3,5)-connected 3D anionic network [Zn2(tmtz)2(sip)2]n2n− with point symbol of (42·6)(42·65·83). The second motif in 1 is the [Zn(tmtz)(H2O)4]n2n+ 1D cationic chain. A polythreading array was formed by a (3,5)-connected 3D anionic network and 1D cationic chains in 1. 2 exhibits a (3,4)-connected 2D network with point symbol of (42·8)(42·6·82·10) and constructs a 3D hydrogen bonding architecture. 1 and 2 are effective catalysts for the degradation of methyl orange in the presence of H2O2. The luminescence and thermal analyses are also performed.
Deep brain reversible encephalopathy: association with secondary antiphospholipid antibody syndrome. (2007)

We present a case of a patient with systemic lupus erythematosus and secondary antiphospholipid syndrome. The patient presented with acute right cerebellar infarction and clinical and imaging evidence of brain stem and bilateral thalamic encephalopathy that resolved completely.
CLOTBUST: Design of a Randomized Trial of Ultrasound-Enhanced Thrombolysis for Acute Ischemic Stroke (2004)

Background: Intravenous tissue plasminogen activator (TPA) therapy can be monitored with 2 MHz transcranial Doppler (TCD). This article describes the design of CLOTBUST (combined lysis of thrombus in brain ischemia using transcranial ultrasound and systemic TPA), the first prospective international multicenter randomized clinical trial of noninvasive externally applied ultrasound to enhance systemic thrombolysis in human stroke. Subjects: Patients with acute ischemic stroke eligible for intravenous TPA therapy within 3 hours of symptom onset who have detectable middle cerebral artery occlusion on a prebolus TCD are included in this trial. All patients receive standard 0.9 mg/kg TPA therapy. Patients are randomized (1:1) to either 2 hours of continuous monitoring with TCD or placebo monitoring. FDA-approved portable diagnostic TCD equipment and standard headframes (Marc series, Spencer Technologies, Seattle, WA) are used. Output of TCD units is set at 100% power achievable at depths of insonation that display the worst TIBI flow grade signals. Methods and End-Points: Acute MCA occlusion on prebolus TCD is defined as thrombolysis in brain ischemia (TIBI) flow grades 0–3. Treating physicians are blinded to randomization assignment, and certified scorers measure stroke severity using the National Institute of Health Stroke Scale (NIHSS). Safety of continuous TCD monitoring is determined by rates of symptomatic (NIHSS score increase by 4+ points) intracerebral hemorrhage within 72 hours after initial symptom onset. Potential enhancement of TPA therapy will be determined using combined primary end-point of early complete recanalization on TCD (TIBI flow grades 4-5), dramatic recovery (NIHSS ≤ 3 points), or decline in the NIHSS ≤ 10 pointsepeatedly measured every 30 minutes within 2 hours after TPA bolus. Other end-points include recovery at 24 hours and 3 months. modified Rankin scores (mRS) are obtained at 90 days, and favorable outcome is determined as NIHSS or mRS scores 0–1. Conclusions: The aim of phase II CLOTBUST trial is to determine the rates of early complete recanalization and dramatic/early clinical recovery in TPA+TCD and TPA groups. The sample size is set at 126 patients since a medium effect size (.50) is anticipated for TPA+TCD group vs TPA alone to achieve combined primary end-point.
<strong>Cardiovascular autonomic neuropathy and risk of kidney function decline in type 1 and type 2 diabetes: findings from the PERL and ACCORD cohorts </strong> (2023)

&lt;p&gt;Previous studies have suggested that cardiovascular autonomic neuropathy (CAN) may predict rapid kidney function decline among persons with diabetes. We analyzed the association between baseline CAN and subsequent glomerular filtration rate (GFR) decline among individuals with type 1 diabetes (T1D) from the Preventing Early Renal Loss in Diabetes (PERL) study (N=469) and with type 2 diabetes (T2D) from the Action to Control Cardiovascular Risk in Diabetes (ACCORD) study (N=7,973). Baseline CAN was ascertained using ECG-derived heart rate variability indices. Its association with GFR slopes, rapid kidney function decline (GFR loss ≥-5 ml/min/1.73 m2/year), and ≥40% GFR loss was evaluated by linear mixed effect, logistic, and Cox regression, respectively. Participants with CAN experienced more rapid GFR decline, by an excess 1.15 (95%CI [-1.93, -0.37], P= 4.0x10-3) ml/min/1.73m2/year in PERL and 0.34 (95%CI [-0.49, -0.19], P= 6.3x10-6) ml/min/1.73m2/year in ACCORD. This translated in 2.11 (95% CI [1.23-3.63], P=6.9x10-3) and 1.39 (95% CI [1.20-1.61], P=1.1x10-5) odds ratios of rapid kidney function decline in PERL and ACCORD, respectively. Baseline CAN was also associated with a greater risk of ≥40% GFR loss events during follow-up (HR=2.60, 95%CI [1.15-5.45], p=0.02 in PERL and HR=1.54, 95%CI [1.28-1.84], P=3.8×10-6 in ACCORD). These associations remained significant after adjustment for potential confounders, including baseline GFR and albuminuria.&lt;strong&gt; Our findings indicate &lt;/strong&gt;that CAN is a strong, independent predictor of rapid kidney function decline in both T1D and T2D. Further studies of the link between these two complications may help develop new therapies to prevent kidney function decline in patients with diabetes. &lt;/p&gt;
<title>Novel single-fiber bidirectional optical add-drop multiplexer for optical distribution networks</title> (2001)

A novel single-fiber bi-directional optical add-drop multiplexer is proposed for wavelength division multiplexing distribution networks. It includes only two optical circulators and two sets of fiber Bragg grating, with advantages of passive, low insertion loss and cost- effective. Self-healing function can be provided passively to the distribution ring network with only one fiber. Very small degradation of bit-error-rate (power penalty &lt; 0.1 dB) is observed when it is used for bi-directional add-drop and transmission.
A Kinship Analysis of Asthma Among the Hutterites (2001)

A formal kinship analysis of asthma in a large Hutterite kindred indicates that cases are significantly more related to one another than are age matched controls. The higher kinship coefficient is shown to be due to an increased probability of the condensed identity state delta 8 which, in turn, is shown to be due to an increased probability of detailed identity state delta 10.
A Randomized, Double-blind, Placebo-Controlled Study of Sibutramine in the Treatment of Binge-Eating Disorder (2003)

Sibutramine is effective and well tolerated in the treatment of obese patients with BED. Its effects address 3 main domains of the BED syndrome, ie, binge eating, weight, and related depressive symptoms.
Developments in reading frame restoring therapy approaches for Duchenne muscular dystrophy (2020)

Currently, 3 AONS are approved. Whether dystrophin levels are sufficient to slowdown disease progression needs to be confirmed. Enhancing AON uptake by muscles is currently under investigation. Gene editing is an alternative, but one that involves practical and ethical concerns. Given the field's momentum, we believe the efficiency of frame-restoring approaches will improve.
Interoperability solutions between smartphones and Wireless Sensor Networks (2012)

The work aims at discussing possible engineering solutions to guarantee the interoperability between smartphones and WSN under high mobility levels. The paper discusses an application scenario where some of the most interesting standards for WSNs can be effectively employed together with smartphones. The architectures supporting interoperable smartphone/WSN systems, considering network topology and functionalities of the nodes are presented together with current network solutions for interoperability.
Quantification of Target Molecules Needed To Detect Microorganisms by Fluorescence In Situ Hybridization (FISH) and Catalyzed Reporter Deposition-FISH (2008)

Fluorescence in situ hybridization (FISH) with rRNA-targeted oligonucleotide probes is a method that is widely used to detect and quantify microorganisms in environmental samples and medical specimens by fluorescence microscopy. Difficulties with FISH arise if the rRNA content of the probe target organisms is low, causing dim fluorescence signals that are not detectable against the background fluorescence. This limitation is ameliorated by technical modifications such as catalyzed reporter deposition (CARD)-FISH, but the minimal numbers of rRNA copies needed to obtain a visible signal of a microbial cell after FISH or CARD-FISH have not been determined previously. In this study, a novel competitive FISH approach was developed and used to determine, based on a thermodynamic model of probe competition, the numbers of 16S rRNA copies per cell required to detect bacteria by FISH and CARD-FISH with oligonucleotide probes in mixed pure cultures and in activated sludge. The detection limits of conventional FISH with Cy3-labeled probe EUB338-I were found to be 370 +/- 45 16S rRNA molecules per cell for Escherichia coli hybridized on glass microscope slides and 1,400 +/- 170 16S rRNA copies per E. coli cell in activated sludge. For CARD-FISH the values ranged from 8.9 +/- 1.5 to 14 +/- 2 and from 36 +/- 6 to 54 +/- 7 16S rRNA molecules per cell, respectively, indicating that the sensitivity of CARD-FISH was 26- to 41-fold higher than that of conventional FISH. These results suggest that optimized FISH protocols using oligonucleotide probes could be suitable for more recent applications of FISH (for example, to detect mRNA in situ in microbial cells).