gebhart/patrepeval huggingface dataset:
A single bisphosphonate infusion does not accelerate fracture healing in high tibial osteotomies (2011)

In this randomized comparison, a single infusion of zoledronic acid increased the pin fixation of the external frame but did not shorten the healing time. In both groups, the external fixator was extracted almost 2 weeks earlier than in previous studies. The early extraction did not cause a loss of correction in either group.
Electronic and magnetic properties of manganite thin films with different compositions and its correlation with transport properties: An X-ray resonant magnetic scattering study (2014)

Here, we present x-ray resonant magnetic dichroism and x-ray resonant magnetic scattering measurements of the temperature dependence of magnetism in Pr-doped La-Ca-Mn-O films grown on (110) NdGaO3 substrates. We observed thermal hysteresis of the ferromagnetism in one film that also showed large thermal hysteresis of ∼18 K in transport measurements. While in a second film of a different nominal chemistry, which showed very small thermal hysteresis ∼3 K in transport measurements, no thermal hysteresis of the ferromagnetism was observed. These macroscopic properties are correlated with evolution of surface magnetization across metal insulator transition for these films as observed by soft x-ray resonant magnetic scattering measurements.
Application of a laser speckle method for determining chemotactic responses of Pseudomonas aeruginosa toward attractants (2006)

Dynamic speckle images are useful tools to characterize the activity of biological tissues. In this paper, this technique was applied to determine chemotaxis responses of <i>Pseudomonas aeruginosa</i> towards attractants. Generalized weighted differences, wavelet entropy and spectral bands decomposition algorithms were used to characterize the speckle activity. Experimental results show regions with different bacterial activity. Dynamic speckle method exhibits a good performance for this application.
Process Evaluation - Steam Reforming of Diesel Fuel Oil (1980)

This project is an evaluation of a proprietary catalyst as a means of steam-reforming diesel fuel oil (Fed. Spec. VV-F-800B, symbol DF-2). A system for testing the catalyst has been designed, built and successfully used to screen operating conditions of temperature, space velocity, and H2O/C ratio. A duration test has been conducted showing the catalyst capable of steam reforming diesel fuel, but with the production of naphthalene after 30 hours. Hydrogen production remained stable through the 86 hours of the test. (Author)
The Pentapeptide Repeat Proteins MfpA Mt and QnrB4 Exhibit Opposite Effects on DNA Gyrase Catalytic Reactions and on the Ternary Gyrase-DNA-Quinolone Complex (2008)

MfpA(Mt) and QnrB4 are two newly characterized pentapeptide repeat proteins (PRPs) that interact with DNA gyrase. The mfpA(Mt) gene is chromosome borne in Mycobacterium tuberculosis, while qnrB4 is plasmid borne in enterobacteria. We expressed and purified the two PRPs and compared their effects on DNA gyrase, taking into account host specificity, i.e., the effect of MfpA(Mt) on M. tuberculosis gyrase and the effect of QnrB4 on Escherichia coli gyrase. Whereas QnrB4 inhibited E. coli gyrase activity only at concentrations higher than 30 microM, MfpA(Mt) inhibited all catalytic reactions of the M. tuberculosis gyrase described for this enzyme (supercoiling, cleavage, relaxation, and decatenation) with a 50% inhibitory concentration of 2 microM. We showed that the D87 residue in GyrA has a major role in the MfpA(Mt)-gyrase interaction, as D87H and D87G substitutions abolished MfpA(Mt) inhibition of M. tuberculosis gyrase catalytic reactions, while A83S modification did not. Since MfpA(Mt) and QnrB4 have been involved in resistance to fluoroquinolones, we measured the inhibition of the quinolone effect in the presence of each PRP. QnrB4 reversed quinolone inhibition of E. coli gyrase at 0.1 microM as described for other Qnr proteins, but MfpA(Mt) did not modify M. tuberculosis gyrase inhibition by fluoroquinolones. Crossover experiments showed that MfpA(Mt) also inhibited E. coli gyrase function, while QnrB4 did not reverse quinolone inhibition of M. tuberculosis gyrase. In conclusion, our in vitro experiments showed that MfpA(Mt) and QnrB4 exhibit opposite effects on DNA gyrase and that these effects are protein and species specific.
Transoral decompression and posterior fusion for rheumatoid atlanto-axial subluxation (1986)

Cervical myelopathy is an uncommon but potentially fatal complication of rheumatoid atlanto-axial subluxation. Computerised myelotomography with three-dimensional reconstruction shows that rheumatoid pannus, together with the odontoid peg, contributes significantly to anterior cervico-medullary compression. These findings were the basis for treatment by transoral anterior decompression and posterior occipitocervical fusion, which removes both bony and soft-tissue causes of compression and allows early mobilisation without major external fixation. We report encouraging results from this combined approach in 14 patients who had progressive neurological deterioration.
Intensity modulated proton therapy: A clinical example (2001)

In this paper, we report on the clinical application of fully automated three-dimensional intensity modulated proton therapy, as applied to a 34-year-old patient presenting with a thoracic chordoma. Due to the anatomically challenging position of the lesion, a three-field technique was adopted in which fields incident through the lungs and heart, as well as beams directed directly at the spinal cord, could be avoided. A homogeneous target dose and sparing of the spinal cord was achieved through field patching and computer optimization of the 3D fluence of each field. Sensitivity of the resultant plan to delivery and calculational errors was determined through both the assessment of the potential effects of range and patient setup errors, and by the application of Monte Carlo dose calculation methods. Ionization chamber profile measurements and 2D dosimetry using a scintillator/CCD camera arrangement were performed to verify the calculated fields in water. Modeling of a 10% overshoot of proton range showed that the maximum dose to the spinal cord remained unchanged, but setup error analysis showed that dose homogeneity in the target volume could be sensitive to offsets in the AP direction. No significant difference between the MC and analytic dose calculations was found and the measured dosimetry for all fields was accurate to 3% for all measured points. Over the course of the treatment, a setup accuracy of +/-4 mm (2 s.d.) could be achieved, with a mean offset in the AP direction of 0.1 mm. Inhalation/exhalation CT scans indicated that organ motion in the region of the target volume was negligible. We conclude that 3D IMPT plans can be applied clinically and safely without modification to our existing delivery system. However, analysis of the calculated intensity matrices should be performed to assess the practicality, or otherwise, of the plan.
Pulmonary embolism following rotator cuff repair (2008)

The data from this review indicates that the risk of pulmonary embolism following surgery for rotator cuff repair is low, but not nonexistent. The most common presenting symptoms of pulmonary embolism were chest pain, shortness of breath, and hypoxia. This study should raise surgeons' awareness about this possible complication following rotator cuff repair surgery.
A novel accurate design method for the hairpin type coupled line bandpass filter (2002)

In this paper, the novel design formula is proposed for the design of a hairpin type coupled-line bandpass filter, which has arbitrary coupled-line lengths and image impedance. Employing the derived design formula promotes convenience in designing and implementing the hairpin type coupled-line bandpass filter. Measured results on fabricated hairpin type coupled-line bandpass filters including a duplexer show good agreements with theoretical results.
Data from Engineered Knottin Peptides: A New Class of Agents for Imaging Integrin Expression in Living Subjects (2023)

&lt;div&gt;Abstract&lt;p&gt;There is a critical need for molecular imaging agents to detect cell surface integrin receptors that are present in human cancers. Previously, we used directed evolution to engineer knottin peptides that bind with high affinity (∼10 to 30 nmol/L) to integrin receptors that are overexpressed on the surface of tumor cells and the tumor neovasculature. To evaluate these peptides as molecular imaging agents, we site-specifically conjugated Cy5.5 or &lt;sup&gt;64&lt;/sup&gt;Cu-1,4,7,10-tetra-azacyclododecane-N,N′,N″,N‴-tetraacetic acid (DOTA) to their N termini, and used optical and positron emission tomography (PET) imaging to measure their uptake and biodistribution in U87MG glioblastoma murine xenograft models. NIR fluorescence and microPET imaging both showed that integrin binding affinity plays a strong role in the tumor uptake of knottin peptides. Tumor uptake at 1 hour postinjection for two high-affinity (IC&lt;sub&gt;50&lt;/sub&gt;, ∼20 nmol/L) &lt;sup&gt;64&lt;/sup&gt;Cu-DOTA–conjugated knottin peptides was 4.47% ± 1.21% and 4.56% ± 0.64% injected dose/gram (%ID/g), compared with a low-affinity knottin peptide (IC&lt;sub&gt;50&lt;/sub&gt;, ∼0.4 μmol/L; 1.48 ± 0.53%ID/g) and c(RGDyK) (IC&lt;sub&gt;50&lt;/sub&gt;, ∼1 μmol/L; 2.32 ± 0.55%ID/g), a low-affinity cyclic pentapeptide under clinical development. Furthermore, &lt;sup&gt;64&lt;/sup&gt;Cu-DOTA–conjugated knottin peptides generated lower levels of nonspecific liver uptake (∼2%ID/g) compared with c(RGDyK) (∼4%ID/g) 1 hour postinjection. MicroPET imaging results were confirmed by &lt;i&gt;in vivo&lt;/i&gt; biodistribution studies. &lt;sup&gt;64&lt;/sup&gt;Cu-DOTA–conjugated knottin peptides were stable in mouse serum, and &lt;i&gt;in vivo&lt;/i&gt; metabolite analysis showed minimal degradation in the blood or tumor upon injection. Thus, engineered integrin-binding knottin peptides show great potential as clinical diagnostics for a variety of cancers. [Cancer Res 2009;69(6):2435–42]&lt;/p&gt;&lt;/div&gt;
Nasal Reflexes (1988)

Nasal reflexes are neurally mediated reactions which arise either through direct stimulation of the nasal mucosa or through stimulation of pathways elsewhere in the body which indirectly involve the nose. The neural pathways involved in these reactions are complex, and the exact nature of the stimuli which trigger these reflexes has not been completely detailed. This review presents a discussion on the innervation of the nose, updates the current understanding about nasal neuropeptides, and then summarizes information about several different types of nasal reflexes.
Pseudo-color image fusion based on intensity-hue-saturation color space (2008)

This paper proposes a pseudo-color image fusion scheme for multi-sensor gray images, which is based on the intensity-hue-saturation (IHS) color space. In the algorithm, registered gray input images are first fused by using a scheme on the basis of gradient-based wavelet structure. Then, the fused gray intensity value is considered as the intensity (I) component of the IHS transform. Hue (H) values are assigned so as to generate human-friendly colors. To emphasize noticeable regions in input images, saturation (S) values are assigned according to H values. To evaluate the proposed algorithm, we compare it with a recently developed algorithm. Experimental results clearly demonstrate that the proposed algorithm provides more a human-friendly and clearer color image. We can also notice that our pseudo-color fused images can provide more visual information than the gray ones.
GARLIC (ALLIUM SATIVUM L.) AND ITS WILD RELATIVES FROM CENTRAL ASIA: EVALUATION FOR FERTILITY POTENTIAL (2004)

Garlic (Allium sativum L.) a popular condiment, is completely sterile, and thus is propagated only vegetatively. According to modern taxonomy, A. sativum and its closest wild relative A. longicuspis form a species complex. The collection of a large number of accessions of these taxa is the only means available for expansion of the genetic variability with regard to yield, quality, tolerance to biotic and abiotic traits, as well as flowering and possibly fertility restoration. A large number of garlic accessions was recently collected in Central Asia, the main center of garlic diversity. Plants were documented according to IPGRI rules, and thereafter evaluated and maintained in the field collections of vegetatively propagated alliums in Israel. The studied accessions were subdivided into two distinct sub-populations: semi-bolters and bolters. Most of flower-producing accessions produced both fertile pollen and receptive stigmas, and true garlic seeds were obtained from 5 accessions, collected in Kazakhstan in 1996-1998. The garlic inflorescence is an umbel-like structure with flower clusters (branches) arising from a common meristem. The flower morphology is typical of the genus Allium. Differentiation of topsets begins in the periphery of the apical surface only after floral differentiation has occurred, and the size, number and rapidity of topset development varies significantly between genotypes. Further studies of flowering physiology and fertility restoration, should focus on bolting genotypes which produce inflorescences with a high ratio of normal flowers to topsets.
Isolation and characterization of two chondroitin lyases from Bacteroides thetaiotaomicron (1983)

Two chondroitin lyases were isolated from the colon anaerobe Bacteroides thetaiotaomicron. Both enzymes had similar molecular weights (104,000 and 108,000) and similar isoelectric points (8.0 and 7.9, respectively). Both enzymes were active against chondroitin sulfates A, B, and C and unsulfated polysaccharides, such as chondroitin and hyaluronic acid, although one of the enzymes was twice as active against chondroitin as the other enzyme. Both had similar Km values for chondroitin sulfates A and C (40 to 70 micrograms/ml) and for chondroitin (300 to 400 micrograms/ml). Neither enzyme could degrade the highly sulfated mucopolysaccharide heparin, but heparin was a potent inhibitor of the activity of both enzymes. Although enzymes I and II were similar in many respects, a comparison of peptides resulting from partial digestion with N-chlorosuccinimide or papain demonstrated that the two proteins are not related.
Cohnella formosensis sp. nov., a xylanolytic bacterium isolated from the rhizosphere of Medicago sativa L (2013)

A Gram-positive, spore-forming, aerobic, rod-shaped, xylanolytic bacterium designated strain CC-Alfalfa-35 T was isolated from the rhizosphere of Medicago sativa L. in Taiwan. Phylogenetic analysis based on 16S rRNA gene sequence showed that strain CC-Alfalfa-35 T was affiliated to the genus Cohnella . Strain CC-Alfalfa-35 T shared 95.3 % pairwise 16S rRNA gene sequence similarity to the type strain of the type species of the genus Cohnella ( Cohnella thermotolerans DSM 17683 T ) besides showing a similarity of 97.4–93.6 % with other recognized species of the genus Cohnella . The DNA–DNA hybridization value between CC-Alfalfa-35 T and Cohnella thailandensis KCTC 22296 T was 37.7 %±1.7 % (reciprocal value, 55.7 %±3.0 %). Predominant cellular fatty acids were iso-C 16 : 0 and anteiso-C 15 : 0 . The polar lipid profile constituted diphosphatidylglycerol, phosphatidylethanolamine, phosphatidylglycerol, lysyl-phosphatidylglycerol, three unidentified phospholipids and three unidentified aminophospholipids. The major respiratory quinone was MK-7 and the DNA G+C content was 58.3 mol%. Strain CC-Alfalfa-35 T contained meso -diaminopimelic acid as the major diamino acid in the cell-wall peptidoglycan. Based on the polar lipid and fatty acid profiles, which were in line with those of C. thermotolerans DSM 17683 T , coupled with additional distinguishing genotypic, phenotypic and chemotaxonomic features, strain CC-Alfalfa-35 T is proposed to represent a novel species within the genus Cohnella , for which the name Cohnella formosensis sp. nov. is proposed. The type strain is CC-Alfalfa-35 T ( = JCM 18405 T = BCRC 80428 T ).
An Electrohydrodynamic Bioprinter for Alginate Hydrogels Containing Living Cells (2014)

In this work we present a bioprinting technique that exploits the electrohydrodynamic process to obtain a jet of liquid alginate beads containing cells. A printer is used to microfabricate hydrogels block by block following a bottom-up approach. Alginate beads constitute the building blocks of the microfabricated structures. The beads are placed at predefined position on a target substrate made of calcium-enriched gelatin, where they crosslink upon contact without the need of further postprocessing. The printed sample can be easily removed from the substrate at physiological temperature. Three-dimensional printing is accomplished by the deposition of multiple layers of hydrogel. We have investigated the parameters influencing the process, the compatibility of the printing procedure with cells, and their survival after printing.
Reassessment of blood donor selection criteria for United States travelers to malarious areas (1991)

In the United States (US), travelers who have had malaria or who have taken antimalarial chemoprophylaxis are deferred as blood donors for 3 years to prevent transfusion-transmitted malaria. To assess the impact of shortening this 3-year exclusion period, national malaria surveillance data from 1972 to 1988 were reviewed. The average annual rate of transfusion-transmitted malaria is 0.25 cases per million units of blood collected. Of 45 reported cases, 38 percent were caused by Plasmodium malariae, 29 percent by P. falciparum, 24 percent by P. vivax, and 9 percent by P. ovale. Thirty-two donors were implicated in 34 cases of transfusion-transmitted malaria. Of 30 implicated donors whose native country was identified, 23 (77%) were foreign nationals and 7 (23%) were from the US. In a review of all imported malaria cases by species and by interval between date of entry and onset of illness, 98 percent of P. falciparum, 86 percent of P. malariae, 76 percent of P. vivax, and 74 percent of P. ovale infections became symptomatic within 6 months of the patient's arrival in the US, regardless of the use of prophylaxis. Shortening to 6 months the donor exclusion period for US travelers to malarious areas would result in a minimum of 70,000 additional blood donors' being made available, with a maximum annual increase of 0.03 additional cases of transfusion-transmitted malaria. The potential benefit of bringing healthy travelers back into the donor pool after a shorter period of exclusion merits consideration by the blood banking industry.
Lanthanide–EDTA complexes covalently bonded on Fe3O4@SiO2 magnetic nanoparticles promote the green, stereoselective synthesis of N-acylhydrazones (2019)

Highly efficient stereoselective synthesis of <italic>E</italic>–<italic>N</italic>-acylhydrazones using magnetic nanoparticles-Ln<sup>3+</sup> as heterogeneous catalysts.
Live streaming performance of the Zattoo network (2009)

A number of commercial peer-to-peer systems for live streaming, such as PPLive, Joost, LiveStation, SOPCast, TVants, etc. have been introduced in recent years. The behavior of these popular systems has been extensively studied in several measurement papers. Due to the proprietary nature of these commercial systems, however, these studies have to rely on a "black-box" approach, where packet traces are collected from a single or a limited number of measurement points, to infer various properties of traffic on the control and data planes. Although such studies are useful to compare different systems from end-user's perspective, it is difficult to intuitively understand the observed properties without fully reverse-engineering the underlying systems. Our paper presents a large-scale measurement study of Zattoo, one of the largest production live streaming providers in Europe, using data collected by the provider. To highlight, we found that even when the Zattoo system was heavily loaded with as high as 20,000 concurrent users on a single overlay, the median channel join delay remained less than 2 to 5 seconds, and that, for a majority of users, the streamed signal lags over-the-air broadcast signal by no more than 3 seconds. To motivate the measurement study, we also present a description of the Zattoo network architecture.
Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions. (1993)

The AML1 gene on chromosome 21 is disrupted in the (8;21)(q22;q22) translocation associated with acute myelogenous leukemia and encodes a protein with a central 118-amino-acid domain with 69% homology to the Drosophila pair-rule gene, runt. We demonstrate that AML-1 is a DNA-binding protein which specifically interacts with a sequence belonging to the group of enhancer core motifs, TGT/cGGT. Electrophoretic mobility shift analysis of cell extracts identified two AML-1-containing protein-DNA complexes whose electrophoretic mobilities were slower than those of complexes formed with AML-1 produced in vitro. Mixing of in vitro-produced AML-1 with cell extracts prior to gel mobility shift analysis resulted in the formation of higher-order complexes. Deletion mutagenesis of AML-1 revealed that the runt homology domain mediates both sequence-specific DNA binding and protein-protein interactions. The hybrid product, AML-1/ETO, which results from the (8;21) translocation and retains the runt homology domain, both recognizes the AML-1 consensus sequence and interacts with other cellular proteins.
<title>Unsupervised image segementation by stochastic reconstruction</title> (1998)

To segment complex and versatile image data from different modalities it is almost impossible to achieve satisfying results without the consideration of contextual information. In this approach, image segmentation is regarded as a high- dimensional optimization task, that can be solved by stochastical methods like evolutionary algorithms (EA). Initially, the iterative algorithm is provided with a set of good-quality sample segmentations. An efficient EA-based learning strategy generates a segmentation for a given target image from the provided samples. This two-level process consists of a global image-based optimization whose convergence is enhanced by locally operating pixel-based Boltzmann processes which restrict the search space to reasonable subsets. The stochastic reconstruction extracts the relevant information from the samples in order to adapt it onto the current segmentation problem, which results in a consistent labeling for the target image. The algorithm works unsupervised, because the range of possible labels and their contextual interpretation is provided implicitly by the sample segmentations. To prove the usefulness of the method experimental results based on both, reproducible phantom images and physiological NMR scans are presented. Moreover, an analysis of the basic segmentation and convergence properties is provided.