gebhart/patrepeval huggingface dataset:
Raman spectroscopic study of ion–ion interaction and its temperature dependence in a poly(propylene-oxide)-based NaCF3SO3 –polymer electrolyte (1990)

Raman scattering measurements have been carried out on poly(propylene oxide) complexed with NaCF3SO3 salt of concentration O:M=30:1 (where O:M is the PO:Na ratio) over a temperature range of 186–360 K in order to study ion–ion associations of the dopant salt and their temperature dependence. Splitting of the symmetric stretching mode of the CF3SO−3 anion into a double band was observed and attributed to the existence of different environments of the anions. A two-component band analysis led to the identification of coexisting dissociated free ions and ion pairs, suggested to be in contact. Below the glass transition temperature, Tg, the intensity of the mode corresponding to the free ions was more or less constant with temperature; the amount of free ions in the glassy state was found to be about 84% of the total salt concentration. Above Tg the amount of dissociated free ions decreased rapidly with temperature in an Arrhenius-type behavior. The resulting reduction of the number of charge carriers has little influence on the conductivity, which is reported to dramatically increase with increasing temperature. It is concluded that the major factor determining the temperature dependence of the conductivity is the mobility rather than the number of charge carriers.
Automated enzyme packed-bed system for the determination of vitamin C in foodstuffs (1991)

A microprocessor controlled flow injection system is described for the determination of vitamin C in foodstuffs. The system is based on amperometric detection at a wall-jet electrode coupled with an ascorbate oxidase packed bed. A commercially available Cartesian robotic auto-sampler-dilutor is used as a means of fully automating the sample handling and dilution. Dithiothreitol (DTT) is used to reduce dehydroascorbic acid to ascorbic acid and to stabilize ascorbic acid standard solutions. Initially, the system was connected in series with a high-performance liquid chromatography column and ultraviolet (UV) detector to allow identification of possible interferents and to allow comparative evaluation of results. The system showed a linear response to the concentration of L-ascorbic acid in the range 1-200 micrograms ml(-1) and was capable of detecting total vitamin C in a range of foodstuffs at a sample throughput of 15 samples h(-1). Correlations to existing methods of 0.98 were obtained.
Nephrometry Score is Associated with Volume Loss and Functional Recovery After Partial Nephrectomy (2012)

R.E.N.A.L. and centrality index nephrometry scores were associated with changes in the percent functional volume preservation and the perioperative functional decrease. Nephrometry scores performed better than diameter alone on statistical analysis. Nephrometry scores may be useful to estimate the likelihood of operative volume loss and by proxy the functional outcome.
Oxidation of Carbon Nanotubes in an Ionizing Environment (2016)

In this work, we present systematic studies on how an illuminating electron beam which ionizes molecular gas species can influence the mechanism of carbon nanotube oxidation in an environmental transmission electron microscope (ETEM). We found that preferential attack of the nanotube tips is much more prevalent than for oxidation in a molecular gas environment. We establish the cumulative electron doses required to damage carbon nanotubes from 80 keV electron beam irradiation in gas versus in high vacuum. Our results provide guidelines for the electron doses required to study carbon nanotubes within or without a gas environment, to determine or ameliorate the influence of the imaging electron beam. This work has important implications for in situ studies as well as for the oxidation of carbon nanotubes in an ionizing environment such as that occurring during field emission.
Correlation of acute cocaine-induced changes in local cerebral blood flow with subjective effects (1993)

The authors administered 48 mg of intravenous cocaine or placebo to eight abstinent cocaine users in a double-blind, crossover design and examined blood flow using single photon emission computed tomography. Cocaine produced significant decreases in frontal cortical and basal ganglia blood flow; these latter correlated negatively with increases in self-ratings of "rush" and "high." The authors conclude that these local effects are compatible with dopaminergic system involvement.
Experimental verification of a secondary recirculation zone in a labyrinth seal (1988)

The existence of a secondary recirculation zone inside the cavities of a labyrinth seal operating at a Reynolds number of 15,000 and a Taylor number of 10,300 has been experimentally verified. A three-dimensional laser Doppler anemometer system was used to measure the complete mean velocity and Reynolds stress tensor distributions in the first, third, fifth and seventh cavities of a seven cavity labyrinth seal which had a clearance of 1.27 mm.
Anti-angiogenic SPARC peptides inhibit progression of neuroblastoma tumors (2010)

Abstract Background New, more effective strategies are needed to treat highly aggressive neuroblastoma. Our laboratory has previously shown that full-length Secreted Protein Acidic and Rich in Cysteine (SPARC) and a SPARC peptide corresponding to the follistatin domain of the protein (FS-E) potently block angiogenesis and inhibit the growth of neuroblastoma tumors in preclinical models. Peptide FS-E is structurally complex and difficult to produce, limiting its potential as a therapeutic in the clinic. Results In this study, we synthesized two smaller and structurally more simple SPARC peptides, FSEN and FSEC, that respectively correspond to the N-and C-terminal loops of peptide FS-E. We show that both peptides FSEN and FSEC have anti-angiogenic activity in vitro and in vivo , although FSEC is more potent. Peptide FSEC also significantly inhibited the growth of neuroblastoma xenografts. Histologic examination demonstrated characteristic features of tumor angiogenesis with structurally abnormal, tortuous blood vessels in control neuroblastoma xenografts. In contrast, the blood vessels observed in tumors, treated with SPARC peptides, were thin walled and structurally more normal. Using a novel method to quantitatively assess blood vessel abnormality we demonstrated that both SPARC peptides induced changes in blood vessel architecture that are consistent with blood vessel normalization. Conclusion Our results demonstrate that SPARC peptide FSEC has potent anti-angiogenic and anti-tumorigenic effects in neuroblastoma. Its simple structure and ease of production indicate that it may have clinical utility in the treatment of high-risk neuroblastoma and other types of pediatric and adult cancers, which depend on angiogenesis.
Expression of ERBB Family Members as Predictive Markers of Prostate Cancer Progression and Mortality (2021)

Our study revealed that specific protein expression patterns of ERBB family members are associated with an increased risk of PC progression and mortality.
Autonomic Neuroreceptor Mechanisms in Brain Vessels (1974)

Intracranial vessels are well innervated by both adrenergic and cholinergic nerves. They possess adrenergic and cholinergic receptors. A contractile response can be provoked by various amines, and noradrenaline can be released from the axons in the perivascular nerve plexus in amounts sufficient to induce strong vasoconstriction. The close relationship between adjacent perivascular cholinergic and adrenergic nerve terminals, also in the neuroeffector area, suggests axonal interaction. It is proposed that the autonomic innervation of brain vessels participates in the control not only of the cerebral circulation but also of associated intracranial pressure phenomena.
Characterization and possible function of adenosine 5′‐triphosphate receptors in activated rat microglia (1994)

1. Purinoceptor agonist-induced currents in untreated (proliferating) and lipopolysaccharide (LPS; 100 ng ml-1)-treated (non-proliferating) rat microglial cells in culture were recorded by the whole-cell patch-clamp technique. These cells have two preferred resting membrane potentials, one at -35 mV and another one at -70 mV. 2. Most experiments were carried out in non-proliferating cells. ATP, ATP-gamma-S and alpha,beta-MeATP (1-1000 microM in all cases) evoked an inward current at a holding potential of -70 mV, followed, in some experiments, by an outward current. At -70 mV 2-methylthio ATP (1-1000 microM) evoked an inward current, whereas at -35 mV it produced an outward current only. 3. When K+ was replaced in the pipette solution by an equimolar concentration of Cs+ (150 mM), the main outward component of the ATP-gamma-S (10 microM) induced response disappeared. Instead, an inward current was obtained. Replacement of K+ by Cs+ did not affect the inward current evoked by 2-methylthio ATP (300 microM). 4-Aminopyridine (1-10 mM), however, almost abolished this current and unmasked a smaller outward current. 4. The rank order of agonist potency was 2-methylthio ATP > ATP > alpha,beta-MeATP. Adenosine and UTP were inactive. Suramin (300 microM) and reactive blue 2 (50 microM) antagonized the effect of 2-methylthio ATP (300 microM). 5. I-V relations were determined by delivering fast voltage ramps before and during the application of 2-methylthio ATP (300 microM). In the presence of extra- (1 mM) and intracellular (150 mM) Cs+, the 2-methylthio ATP-evoked current crossed the zero current level near 0 mV. When both Cs+ (1 mm) and 4-aminopyridine (1 mM) were present in the bath medium, the intersection of the 2-methylthio ATP current with the zero current level was near - 75 mV.6. 2-Methylthio ATP (1-1I000 MicroM) induced the same inward current both in proliferating and nonproliferating microglia. However, the depolarizing response to 2-methylthio ATP (300 MicroM) was larger and longer-lasting in the proliferating cells. When the free Ca2+ concentration in the pipettes was increased from the standard 0.01 to 1 MicroM, the amplitude and duration of this depolarization was increased in non-proliferating cells. 4-Aminopyridine (1 mM) enhanced the duration, but not the amplitude of responses.7. ATP and its structural analogues stimulate microglial purinoceptors of the P2Y-type. This leads to the opening of non-selective cationic channels and potassium channels. Depending on the resting membrane potential, depolarization or hyperpolarization prevails. Although the inward current produced by 2-methylthio ATP is of similar amplitude in proliferating and non-proliferating microglia, the resulting depolarization is smaller in the latter cell type because of the presence of voltage-sensitive, outwardly rectifying potassium channels.
ChemInform Abstract: Highly Stereoselective Synthesis of Trisubstituted α,β‐Unsaturated Sulfoxides by Heck Reaction. (2001)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Study of Thread Level Parallelism in a Video Encoding Application for Chip Multiprocessor Design (2002)

In media applications there is a high level of available thread level parallelism (TLP). In this paper we study the intra TLP in a video encoder. We show that a well-distributed highly optimized encoder running on a symmetric multiprocessor (SMP) system can run 3.2 faster on a 4-way SMP machine than on a single processor. The multithreaded encoder running on an SMP system is then used to understand the requirements of a chip multiprocessor (CMP) architecture, which is one possible architectural direction to better exploit TLP. In the framework of this study, we use a software approach to evaluate the dataflow between processors for the video encoder running on an SMP system. An estimation of the dataflow is done with L2 cache miss event counters using Intel&reg; VTune<sup>TM </sup>performance analyzer. The experimental measurements are compared to theoretical results.
Virtual Experiences of Metaverse Using Mobile Type Head-Mounted Displays and Their Applicability (2022)

The concept of a 3D experience using the Google Cardboard VR headset and cell phones is discussed in terms of its educational effect. As for the video component, content on YouTube as a 360°VR video is used. The following three topics are included in this project: skydiving, lunar exploration, and deep-sea exploration. In some organizations, groups of faculty and student members are asked to participate in such an activity to experience 3D using a cell phone and YouTube along with the VR headset. The authors plan to analyze the results using a 5-point scale. A similar experiment is already in progress. It involves the use of a different VR headset tool (Oculus Quest). Since the contents of both activities are similar, the purpose of this experiment is to compare and verify the advantages and disadvantages of using a VR cardboard headset and a cell phone, as well as to identify the advantages and disadvantages of using a cell phone.
Optimal Quantum Control of Multimode Couplings between Trapped Ion Qubits for Scalable Entanglement (2014)

We demonstrate entangling quantum gates within a chain of five trapped ion qubits by optimally shaping optical fields that couple to multiple collective modes of motion. We individually address qubits with segmented optical pulses to construct multipartite entangled states in a programmable way. This approach enables high-fidelity gates that can be scaled to larger qubit registers for quantum computation and simulation.
MutatorandMULETransposons (2015)

A distinguishing feature of transposable elements (TEs) is their propensity to induce mutations. Among the most mutagenic of all TEs are the Mutator elements of maize. Lines carrying large numbers of these elements can exhibit mutation frequencies 50 to 100 times that of background (1,2). This is due to a very high transposition frequency, which can exceed one new insertion per element per generation (3,4), as well as a propensity to insert into or near genes (5). Because they are so mutagenic, Mutator elements have been very useful in both forward and reverse genetic screens in maize and recent high-throughput methodologies have only made the system more so (6). However, in addition to its utility, the Mutator system has also provided important clues as to the consequences of unrestrained TE activity, and the means by which active TEs are controlled by their host. This chapter will provide a review of the biology, regulation, evolution and uses of this remarkable transposon system, with an emphasis on recent developments in our understanding of the ways in which this TE system is recognized and epigenetically silenced.
Tuberous breast deformity: A modified technique for single-stage correction (2016)

The aesthetic results have been very good in terms of shape, volume, symmetry and patient satisfaction. A historical summary of the development of techniques for correction of tuberous breast is presented along with description of our method and its results.
Microwave Generation Using Sheet Relativistic Electron Beams (1977)

Potential advantages in the use of a sheet electron beam for generation of high-power microwave signals are discussed and preliminary experiments to establish their applicability are reported. An examination indicates that sheet beams probably have greatest utility in the frequency, range 10-100 GHz.
Abstract 11800: Whole Exome Sequencing in a Large Pedigree With DCM Identifies a Novel Mutation in RBM20 (2015)

Background and hypothesis: Familial dilated cardiomyopathy (DCM) is genetically heterogeneous and is associated with mutations in at least 30 different genes. None of these genes have an expected diagnostic yield of more than 10% complicating genetic diagnosis. Whole exome sequencing (WES) is a powerful alternative for the identification of the causal gene, however variant interpretation remains challenging. We performed WES in a large family with autosomal dominant DCM complicated by end stage heart failure and ventricular arrhythmias. The index of this family was evaluated previously by means of targeted gene panel analysis including 28 genes, but no causal mutation was found. Methods and results: WES was applied on 2 affected cousins. First, shared heterozygous variants (single nucleotide variants, small insertions and deletions) located inside the exon or at the exon/intron boundary were selected. Synonymous variants were excluded, except if they were located at the exon/intron boundaries. Variants with a minor allele frequency of &gt;0.1% in publically available exome databases (1000 Genomes and ESP) were excluded. Furthermore, variants that were present in an in-house exome cohort performed for other disease entities were also excluded since these probably represent local SNV’s. The remaining 19 variants were evaluated using a comprehensive scoring system that includes different in-silico analysis tools, orthologous and paralogous conservation and population frequencies. Subsequently Sanger sequencing was performed for 10 variants that were classified as likely pathogenic (N=1) or variants of unknown significance (N=9) according to the scoring system in order to confirm the presence of the variant and to evaluate co-segregation. Only one variant in exon 9 of the RBM20 gene (c.2714T&gt;A, p.Met950Lys, NM_001334363) showed full co-segregation in the 7 affected family members resulting in a maximum 2-point LOD score of 2.1 and suggesting this as the pathogenic mutation responsible for the phenotype. Recently mutations in RBM20 have been linked to dilated cardiomyopathy caused by defective splicing of the giant sarcomeric protein titin. Conclusions: We report the identification of a novel mutation in RBM20 by WES in a large pedigree with DCM.
Vibrational analysis of power tools using a novel three-dimensional scanning vibrometer (2004)

Scanning Laser Doppler Vibrometers (SLDV) are widely used in product development. Power tools as for example percussion drilling machines are known to be noisy and vibrating. It is state of the art to reduce the noise and vibration by finding the sources therefrom with LDV. Although these data give important information about the vibrational behavior, for a deeper understanding three dimensional vibration data is required. Therefore, for the first time measurements on power tools have been performed using a novel 3D SLDV, which simultaneously measures three components of the vibration vectors using three vibrometers. Power tools are observed under operating conditions close to reality, operated by a human. As the device under test performs movements in all directions, the three laser beams do not perfectly intersect. It is shown, that the introduced error can be neglected for low frequencies. Results are presented for a percussion drilling machine and a random orbit sander.
Fabrication and Characterization of Gate-Connected 1T2C-Type Ferroelectric Memory with Paired Bi4 − xLaxTi3O12 Capacitors (2003)

A gate-connected 1T2C-type ferroelectric memory, in which the bottom electrodes of paired ferroelectric capacitors are connected to the gate electrode of an underlying FET (field effect transistor) on the field oxide region, was fabricated using a Bi4 − xLaxTi3O12 (BLT) film and its electrical properties were characterized. The ID-VG (drain current-gate voltage) characteristics of a FET combined with a single ferroelectric capacitor showed that the paired capacitors had almost the same ferroelectric property. It was found in the readout operation that there existed an optimum voltage to maximize the drain current on/off ratio between datum ‘1’ and datum ‘0,’ and that the maximum ratio was as large as 6 × 104. It was also found that the drain current level remained constant, even if the readout operation was repeatedly conducted. It was concluded from these results that the 1T2C-type memory was successfully fabricated using the proposed process and operated properly.
High-Throughput, Noninvasive Imaging of Root Systems (2012)

Root systems are complex structures key to plant health. The three-dimensional distribution of the root system, known as the root architecture, is important for optimal uptake of water and nutrients, as well as anchorage in the soil. Despite the importance of root systems, little is known about the genes that control root architecture, in part because of the difficulty of non-destructively viewing root systems. The Benfey lab has developed a gel-based imaging method to non-invasively examine root system architecture over time. Root systems of a variety of plant species can be quickly imaged daily or weekly. The platform is relatively inexpensive, high-throughput, and is ideally suited for researchers aiming to understand the genetic control of root architecture. Here we describe the application of this method to rice and maize root systems.
Measurement of the electrostatic charge in airborne particles: II - particle charge distribution of different aerosols (2006)

This work gives sequence to the study on the measurement of the electrostatic charges in aerosols. The particle charge classifier developed for this purpose and presented in the previous paper (Marra and Coury, 2000) has been used here to measure the particle charge distribution of a number of different aerosols. The charges acquired by the particles were naturally derived from the aerosol generation procedure itself. Two types of aerosol generators were used: the vibrating orifice generator and turntable Venturi plate generator. In the vibrating orifice generator, mono-dispersed particles were generated by a solution of water/ethanol/methylene blue, while in the rotating plate generator, six different materials were utilized. The results showed no clear dependence between electric charge and particle diameter for the mono-dispersed aerosol. However, for the poly-dispersed aerosols, a linear dependence between particle size and charge could be noticed.
Supplementary Figure 1 from HDAC6 Inhibition Restores Ciliary Expression and Decreases Tumor Growth (2023)

&lt;p&gt;PDF file - 1169K, Cilia staining in AccuMax Array A205(II)&lt;/p&gt;
Real-time programming in the concurrent object-oriented language TAO (2002)

The paper introduces the concurrent object oriented language TAO and then considers how real time support can be added. The paper describes how concurrent objects can be mapped to sporadic and periodic tasks through inheritance within the concurrent object oriented language TAO.
Regioselective Formation of (E)‐β‐Vinylstannanes with a Topologically Controlled Molybdenum‐Based Alkyne Hydrostannation Catalyst (2018)

The regioselective formation of (E)-β-vinylstannanes has been a long-standing challenge in transition-metal-catalyzed alkyne hydrostannation. Herein, we report a well-defined molybdenum-based system featuring two encumbering m-terphenyl isocyanides that reliably and efficiently delivers (E)-β-vinylstannanes from a range of terminal and internal alkynes with high regioselectivity. The system is particularly effective for aryl alkynes and can discriminate between alkyl chains of low steric hindrance in unsymmetrically substituted dialkyl alkynes. Catalytic hydrostannation with this system is also characterized by an electronic effect that leads to a decrease in regioselectivity when electron-withdrawing groups are present on the alkyne substrate.
Combining High-Resolution Pulsed TIVA and Nanoprobing Techniques to Identify Drive Strength Issues in Mixed-Signal Circuits (2010)

Abstract This paper uses an interesting case study to highlight high-resolution pulsed thermal-induced voltage alteration (TIVA) with solid immersion lens (SIL) as a technique to isolate a temperature-sensitive failure in mixed-signal circuitry, followed by circuit analysis and nanoprobing to confirm a drive strength issue caused by a process change.