gebhart/patrepeval huggingface dataset:
Toward the Development of “CO2-philic” Hydrocarbons. 1. Use of Side-Chain Functionalization to Lower the Miscibility Pressure of Polydimethylsiloxanes in CO2 (1999)

Previous fundamental work on the solvent properties of carbon dioxide by the research groups of McHugh, DeSimone, Johnston, and Eckert has been used as a road map for the design of materials that will be miscible with CO2 at relatively moderate pressures. In this initial work, judicious side chain functionalization of an oligomeric silicone has been shown to produce a material whose phase behavior in CO2 resembles that of a fluorinated polyether. The phase behavior results are quite dramatic in that addition of only five ester-functional side chains to the silicone polymer lowers the cloud point curve at 22 °C by 2500 psi. It was also observed that addition of simple alkyl side chains raises the cloud point pressures of the silicone in CO2. This latter observation is consistent with results on the phase behavior of poly(n-alkyl acrylates) in CO2 that showed that increasing alkyl content (i.e., increasing alkyl chain length) also raises cloud point pressures.
Comparison between Holstein Cow’s Milk and Japanese-Saanen Goat’s Milk in Fatty Acid Composition, Lipid Digestibility and Protein Profile (2006)

The fatty acid composition, the lipid digestibility and protein profile of Japanese-Saanen goat's milk were characterized. Caprine milk contained substantial quantities of C(4:0) to C(10:0) fatty acids as compared with Holstein cow's milk. The lipids of the former showed significantly higher digestibility in vitro by porcine lipase than those of the latter (P<0.05). As determined by SDS-PAGE, the respective contents of alpha(s1)-casein, one of the major allergens, were 3.9% and 33.7% in caprine and bovine milk.
Nanotribology and nanomechanics of AFM probe-based data recording technology (2008)

With the advent of scanning probe microscopes, probe-based data recording technologies are being developed for ultrahigh areal density recording, where the probe tip is expected to be scanned at velocities up to 100 mm s−1. In one technique, a conductive atomic force microscope (AFM) tip is scanned over a phase change chalcogenide medium and phase change is accomplished by applying either a high or low magnitude of current which heats the interface. Another technique is ferroelectric data storage, where a conducting AFM tip is scanned over a lead zirconate titanate (PZT) film, a ferroelectric material. Ferroelectric domains can be polarized by applying short voltage pulses between the AFM tip and the bottom electrode layer that exceed the coercive field of the PZT film, resulting in nonvolatile changes in the electronic properties. Tip wear is a serious concern in both data storage methods. The understanding and improvement of tip wear, particularly at the high velocities needed and at high interface temperatures for high data rate recording, is critical to the commercialization of these data storage technologies.
Digitally-Controlled Electrical Balance Duplexer for Transmitter-Receiver Isolation in Full-Duplex Radio (2016)

Today’s traditional radio systems exploit two techniques to transmit and receive which are Time Domain Duplexing (TDD) and Frequency Domain Duplexing (FDD). These two techniques allow bidirectional communication exploiting different frequencies or time-slots for the transmission and receiving operations. The ongoing research on wireless communications is currently active under in-band Full-Duplex (FD) radio communications, where co-located transmitter and receiver are operating simultaneously at the same central frequency doubling the spectral efficiency. The main technical challenge consists in suppressing the strong self-interference (SI) which is caused by the transmitting (TX) leakage into the receiving (RX) chain. Thus, FD transceivers need to provide high TX-RX isolation requirements in order to suppress the SI. Different methods are employed to mitigate the effect of the SI pursuing then FD operation. Generally, passive isolation between the TX and RX in the radio frequency (RF) domain can be built on specific antenna technologies or hybrid junction based electrical balance duplexers (EBD). On top of these, active SI cancellation is also typically required, either at analog/RF stages or digital baseband or both. &#13;\nThis thesis work presents a novel digitally-controlled electrical balance duplexer prototype capable of inband FD radio communications. The developed EBD prototype works in the ISM-Band, at 2.4-2.48 GHz, and can achieve TX to RX isolation of 53 dB across an 80 MHz instantaneous bandwidth. The prototype is composed of three parts, namely coupled line hybrid junction, triple-Pi balancing impedance and antenna tuning unit (ATU) which are all realized with commercial off-the-shelf components and implemented over a two layer FR4 board. The EBD contains also a self-adaptive or self-healing digital control system enabling automatic tracking of time-varying antenna impedance characteristics, providing robustness against fast changes in the surrounding environment and against user interactions. In addition to the architecture and operating principle descriptions, we also provide actual RF measurements at 2.4 GHz ISM band with real antenna connected, demonstrating the achievable isolation levels with different bandwidths and when operating in different environmental conditions. Furthermore, isolation performances are measured when operating with different antennas and under a low-cost highly nonlinear power amplifier.
Cell Cycle Activation of Peripheral Blood Stem and Progenitor Cells Expanded Ex Vivo with SCF, FLT‐3 Ligand, TPO, and IL‐3 Results in Accelerated Granulocyte Recovery in a Baboon Model of Autologous Transplantation but G 0 /G 1 and S/G 2 /M Graft Cell Content Does Not Correlate with Tranplantability (2001)

Ex vivo expansion is a new strategy for hematopoietic stem and progenitor cell transplantation based on cytokine-induced amplification to produce grafts of controlled maturity. If the cell cycle position of CD34(+) cells has been reported to govern their engraftment potential, the respective role of stem and progenitor cells in short- and long-term hematopoietic recovery remains debated. Studies focused on long-term engraftment potential suggest impairment when using cultured grafts, but the capacity to sustain short-term recovery is still controverted. The aim of this study was: A) to evaluate the consequences of cell cycle activation on short and long-term engraftment capacity, and B) to determine if cell cycle status of grafts could predict hematopoietic recovery. We showed in a nonhuman primate model of autologous peripheral blood stem and progenitor cell transplantation that cell cycle activation of CD34(+) cells in the presence of stem cell factor + FLT3-ligand + thrombopoietin + interleukin 3 (six days of culture) which induced G1 and S/G2/M cell amplification (G0: 6.1% +/- 2.8%; G0/G1: 64.2% +/- 7.2%; S/G2/M: 30.4% +/- 7.3% respectively of expanded CD34(+) cells on average) resulted in the acceleration of short-term granulocyte recovery. By contrast, G0/G1 and S/G2/M cell content of expanded grafts did not correlate with short- or long-term engraftment.
A detector for monitoring the onset of cavitation during therapy-level measurements of ultrasonic power (2004)

Acoustic cavitation occurring in the water path between a transducer and the target of a radiation force balance can provide a significant source of error during measurements of ultrasonic power. These problems can be particularly acute at physiotherapy levels (>1 W), and low frequencies (⩽ 1 MHz). The cavitating bubbles can absorb and scatter incident ultrasound, leading to an underestimate in the measured power. For these reasons, International Specification standards demand the use of degassed water. This imposes requirements that may actually be difficult to meet, for example, in the case of hospitals. Also, initially degassed water will rapidly re-gas, increasing the likelihood of cavitation occurring. For these reasons, NPL has developed a device that monitors acoustic emissions generated by bubble activity, for detecting the onset of cavitation during power measurements. A commercially available needle hydrophone is used to detect these emissions. The acoustic signals are then monitored using a Cavitation Detector (CD) unit, comprising an analogue electrical filter that may be tuned to detect frequency components generated by cavitating bubbles, and which provides an indication of when the measured level exceeds a pre-defined threshold. This paper describes studies to establish a suitable detection scheme, the principles of operation of the CD unit, and the performance tests carried out with a range of propagation media.
SU-E-T-372: Dosimetric Comparison of Craniospinal Irradiation Using Different Tomotherapy Techniques (2014)

Purpose: TomoHDA can treat with fixed jaws, dynamic jaws, and fixed gantry using either 3DCRT or IMRT. This study compares PTV coverage, OAR sparing, and beam-on-time (BOT) among these techniques for craniospinal irradiation (CSI). Methods: This study includes ten CSI patients treated to 23.4 Gy/13 fractions with Hi-Art 3.0 unit (HT-IMRT fixed 5 cm jaw). New plans were regenerated with 5 cm jaw for TomoHDA Hi-Art 5.0 using dynamic jaw (HD-IMRT), TomoDirect_IMRT (TD-IMRT), and Helical Tomotherapy 3DCRT (HT-3DCRT using 5 cm and 2.5 cm jaws with various pitches). Studied parameters include PTV mean dose, D95 (dose covering 95% of PTV), Paddick's conformity index (CI) and homogeneity index (HI – standard deviation of PTV dose/average PTV dose), BOT, and average OAR doses. Results: PTV coverage from these techniques were comparable (p>0.05). The main differences were in OAR sparing; HDIMRT reduced more OAR doses for lenses, bladder and rectum compared to HT-IMRT. For the sparing of visceral organs: liver, lung, heart, and kidneys, the three IMRT techniques gave comparable results. HD-IMRT gave best heart sparing; HT-IMRT best kidney sparing. Liver and lung doses were best reduced by TD-IMRT. All three IMRT techniques gave comparable BOT. OARs sparing was achieved for jaw size of 2.5 cm. HI was also improved but with doubling of BOT. Increasing the pitch number from 0.2 to 0.43 produced no significant improvement in OAR sparing but CI and HI did improve. Conclusion: HT-3DCRT, HT-IMRT, HD-IMRT or TD-IMRT techniques give comparable PTV coverage but the three IMRT plans better spared OARs compared with 3DCRT plans. Dynamic jaw plan is superior to fixed jaw plan to spare more OAR doses at field edge. TD_IMRT cannot reduce BOT for CSI patient but for sparing certain OAR, TD-IMRT may be used to avoid the beam going through the structures of interest.
Quasi-Phase-Matched Parametric Fluorescence in Poled Silica Fibres (1999)

Recently the demonstration of highly efficient Second-Harmonic Generation (SHG) in periodically poled silica fibres (PPSF) [1], has opened new prospects for the realisation of second-order nonlinear optical processes in all-fibre devices.
A Branch-and-Cut Algorithm Without Binary Variables for Nonconvex Piecewise Linear Optimization (2006)

We give a branch-and-cut algorithm for solving linear programs (LPs) with continuous separable piecewise-linear cost functions (PLFs). Models for PLFs use continuous variables in special-ordered sets of type 2 (SOS2). Traditionally, SOS2 constraints are enforced by introducing auxiliary binary variables and other linear constraints on them. Alternatively, we can enforce SOS2 constraints by branching on them, thus dispensing with auxiliary binary variables. We explore this approach further by studying the inequality description of the convex hull of the feasible set of LPs with PLFs in the space of the continuous variables, and using the new cuts in a branch-and-cut scheme without auxiliary binary variables. We give two families of valid inequalities. The first family is obtained by lifting the convexity constraints. The second family consists of lifted cover inequalities. Finally, we report computational results that demonstrate the effectiveness of our cuts, and that branch-and-cut without auxiliary binary variables is significantly more practical than the traditional mixed-integer programming approach.
Procedural authoring of solid models (2003)

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2003.
Prorocentrin: An Extracellular Siderophore Produced by the Marine Dinoflagellate Prorocentrum minimum (1983)

Prorocentrin, a putative iron transport compound, has been extracted from the filtrates of Prorocentrum minimum cultures by XAD-2 resin. Production of prorocentrin can be stimulated by culturing Prorocentrum minimum under conditions of iron deficiency. The iron(III) complex of prorocentrin has an ultraviolet-visible absorption spectrum typical of hydroxamate siderophores.
Effects of chemical composition and temperature of heating on the infrared spectra of Li-saturated dioctahedral smectites. (II) Near-infrared region (2000)

Abstract Diffuse reflectance spectra in the near-infrared region are presented for Li-saturated smectites heated up to 200°C. The smectites included three montmorillonites, an Fe-beidellite and a ferruginous smectite. Unheated samples showed a complex band near 7060 cm -1 assigned to the first overtone of the OH-stretching mode of structural hydroxyl groups and bound H 2 O. The OH combination bands appeared in the 4600-4300 cm -1 region. Spectra of heated montmorillonites showed an upward shift and splitting of the OH-overtone band into two components near 7170 and 7110 cm -1 . The presence of a band near 7170 cm -1 , assigned to the overtone of the AlMgLiOH-stretching vibration, implied that local trioctahedral domains were created upon Li(I) fixation in the previously vacant octahedral positions of montmorillonites. The OH combination bands were shifted to higher frequencies and a new band appeared near 4472 cm -1 in the spectra of montmorillonites heated to temperatures in excess of 130°C. No features indicating Li(I) in the structure of Fe-beidellite or ferruginous smectite were observed in the NIR spectra.
Revealing the Microstructural Information of the Quasi-Plastic Zone in a Boron Carbide Using the Advanced Precession Electron Diffraction Technique (2019)

There has been a spike of scientific interest in studying the amorphous shear bands due to its ability to deteriorate ballistic performance in boron carbide. The extreme shear imposed during indentation experiments with a sharp indenter tip (Berkovich and cube corner) could activate amorphization even at very small loads [1]. Amorphous bands are characterized by the loss of crystallinity order in small zones, usually nanometers in width, containing within a crystalline volume with complex features Previous transmission electron microscopy (TEM) characterization of the quasi-plastic zones underneath the indents are very localized, mainly focusing on the amorphous shear bands There lacked an overall microstructural understand of the quasi-plastic zones in general due to the large residual strain and complex diffraction contrast.
Relationship between transient DNA hypomethylation and erythroid differentiation of murine erythroleukemia cells. (1988)

The state of DNA methylation in mouse erythroleukemia (MEL) cells has been analyzed in relation to commitment to differentiation in response to treatment with hexamethylenebisacetamide (HMBA). Previous experiments have shown that induction by HMBA involves transient genome-wide hypomethylation of DNA that is achieved by replacement of 5-methylcytosine with cytosine residues. The experiments described in the present communication revealed that hypomethylation is a very early event in the process of differentiation. Exposure of the cells to 3-deazaadenosine, an adenosine analog, in combination with homocysteine, resulted in the intracellular accumulation of 3-deazaadenosylhomocysteine, which caused an inhibition of HMBA-induced hypomethylation that was correlated with a comparable inhibition of differentiation. While these experiments suggest that hypomethylation is a necessary step in the process of differentiation, other experiments reported here indicate that hypomethylation of DNA may be necessary but not sufficient to trigger the whole program of differentiation in MEL cells. We found, for example that exposure of the cells to cycloheximide during the first 24 hr of induction by HMBA resulted in complete inhibition of differentiation without significant effect on the HMBA-induced hypomethylation. This result also indicates that the enzymatic machinery required for the hypomethylation of DNA is present in uninduced cells.
Arrival angular profile modelling at mobile station for cellular systems (2010)

Spatial processing techniques such as Adaptive Array Antenna (AAA) and Multi-Input-Multi-Output (MIMO) have being considered for use in the next generation mobile cellular systems. In order to accurately estimate the performance of these spatial processing techniques in wide-band mobile communications, we need a time-spatial path model that can present the delay profile and the spatial arrival angular profiles at the same time. We proposed a physical time-spatial path model as a variant of Clark's scattering model and showed by theory and by computer simulation that the proposed model can well match field measurement results with regard to the arrival angular distribution at the BS and the delay time distribution in urban and suburban areas by setting key parameters to appropriate values. In this paper, we derive an arrival angular profile model at the MS from our proposed physical time-spatial path model. We then carried out field measurements in typical suburban and urban area in Tokyo. We show that the proposed arrival angular profile model can well match the field measurement results by setting the parameters to appropriate values.
Animal Models of Zika Virus Sexual Transmission (2020)

ZIKV was first identified in the 1940s as a mosquito-borne virus; however, sexual transmission, which is uncommon for arboviruses, was demonstrated more than 60 years later. Tissue culture and animal models have allowed scientists to study how this transmission is possible. Immunocompromised mice infected with ZIKV had high viral loads in their testes, and infection of immunocompetent female mice was achieved following intravaginal inoculation or inoculation via mating with an infected male. These mouse studies lead researchers to investigate the individual components of the male reproductive system. In cell culture and mouse models, ZIKV can persist in Sertoli and germ cells of the testes and epithelial cells in the epididymis, which may lead to sexual transmission even after ZIKV has been cleared from other tissues. ZIKV has also been studied in nonhuman primates (NHPs), which appears to mimic the limited human epidemiological data, with low rates of symptomatic individuals and similar clinical signs. Although refinement is needed, these animal models have proven to be key in ZIKV research and continue to help uncovering the mechanisms of sexual transmission. This review will focus on the animal models used to elucidate the mechanisms of sexual transmission and persistence of flaviviruses.
Long-Term Follow-up of Unilateral Pallidotomy in Advanced Parkinson's Disease (2000)

In the group of patients with advanced Parkinson's disease who could be enrolled in our long-term follow-up study of unilateral posteroventral medial pallidotomy (20 patients from the original cohort of 40), significant early improvements in off-period contralateral signs of parkinsonism were sustained for up to five and a half years. There was a sustained significant improvement in on-period contralateral dyskinesia but not in other on-period signs of parkinsonism.
Développement d'un appareil de séparation préparative de protéines par focalisation entre membranes isoélectriques (1991)

These Ecole polytechnique federale de Lausanne EPFL, n° 958 (1991) Reference doi:10.5075/epfl-thesis-958Print copy in library catalog Record created on 2005-03-16, modified on 2016-08-08
Ultra-Selective Flexible Add-Drop Multiplexer Using Rectangular Stimulated Brillouin Scattering Filters (2015)

International audience
Oxaliplatin-induced acute tubulointerstitial nephritis: Two case reports (2017)

Oxaliplatin is a platinum compound commonly used in the treatment of advanced colorectal cancer. This report describes two patients who had received repetitive combination chemotherapy including oxaliplatin for the treatment of metastatic colon cancer and who visited the emergency department with acute kidney injury several days after experiencing a hypersensitivity reaction to oxaliplatin. In both cases, the pathologic diagnosis was acute tubulointerstitial nephritis, and corticosteroid therapy resulted in improved renal function. Induction of acute tubulointerstitial nephritis by oxaliplatin has rarely been reported. .
Drug evaluation: tefibazumab--a monoclonal antibody against staphylococcal infection. (2006)

Inhibitex Inc is investigating tefibazumab, a humanized monoclonal antibody specific for the fibrin-binding surface epitope clumping factor A protein (expressed on the surface of most Staphylococcus aureus strains), for the potential intravenous prevention and/or treatment of S aureus infections. In June 2006, Inhibitex was seeking to outlicense certain development rights to the drug. Pending the outcome of partnering discussions, Inhibitex suspended the initiation of any additional clinical trials of tefibazumab. Preclinical in vivo studies were ongoing at that time.
Expression and prognostic value of L1-CAM in breast cancer (2009)

The L1 adhesion molecule (L1-CAM) is associated with impaired prognosis in many carcinomas. However, limited information about its expression in breast cancer tissue is available. Therefore, we carried out an analysis on L1 expression in primary breast cancers using a combination of Western blot, DNA-microarray analysis and immunohistochemistry. We observed L1 protein and mRNA overexpression in 14-15% of the carcinomas and this was confirmed by immunohistochemical staining. High L1 expression was associated with nodal involvement, high grading, human epidermal growth receptor 2 (Her-2), plasminogen activator inhibitor 1 (PAI-1) and vascular endothelial growth factor (VEGF) expression and a negative estrogen receptor (ER) status, but not with neuroendocrine markers. Moreover, patients with tumors showing high L1-CAM expression had a shorter disease-free and overall survival. Given the emerging functional role of L1 in promoting tumor cell migration, invasion, tumor growth and metastasis, our results suggest that L1 may have this function in breast cancer as well.
Cyclospora cayetanensis (2003)

I. BACKGROUND Cyclospora cayetanensis is a protozoan parasite of humans that causes diarrheal illness after colonizing the mucosal epithelium of the small intestine. In retrospect, this coccidian parasite was first described in persons from Papua New Guinea in 1979 (1), but the specific identification as a Cyclospora species would not occur until 1993 (2). In the intervening years the parasite was alternately described as either a large variant of Cryptosporidium, a blue-green alga (cyanobacteriumlike), or an unidentified coccidian. The actual nature was not discerned until stool specimens were stored without a fixative for sufficient time to allow the undifferentiated oocysts to sporulate and reveal both sporocysts and sporozoites (2,3).