gebhart/patrepeval huggingface dataset:
Molecular Docking and Aberration-Corrected STEM of Palladium Nanoparticles on Viral Templates (2016)

Viral templates are highly versatile biotemplates used for the synthesis of nanostructured materials. Rotavirus VP6 self-assembles into nanotubular hollow structures with well-defined diameters and variable lengths, serving as a nucleic acid-free biotemplate to synthesize metal nanoparticles of controlled size, shape, and orientation. Molecular docking simulations show that exposed residues (H173-S240-D242 and N200-N310) of VP6 have the ability to specifically bind Pd(II) ions, which serve as nucleation sites for the growth and stabilization of palladium nanoclusters. Using VP6 nanotubes as biotemplates allows for obtaining small Pd particles of 1–5 nm in diameter. Advanced electron microscopy imaging and characterization through ultra-high-resolution field-emission scanning electron microscopy (UHR-FE-SEM) and spherical aberration-corrected scanning transmission electron microscopy (Cs-STEM) at a low voltage dose (80 kV) reveals, with high spatial resolution, the structure of Pd nanoparticles attached to the macromolecular biotemplates.
A region and category confidence-based multi-task network for carotid ultrasound image segmentation and classification (2023)

The segmentation and classification of carotid plaques in ultrasound images play important roles in the treatment of atherosclerosis and assessment for the risk of stroke. Although deep learning methods have been used for carotid plaque segmentation and classification, two-stage methods will increase the complexity of the overall analysis and the existing multi-task methods ignored the relationship between the segmentation and classification. These will lead to suboptimal performance as valuable information might not be fully leveraged across all tasks. Therefore, we propose a multi-task learning framework (RCCM-Net) for ultrasound carotid plaque segmentation and classification, which utilizes a region confidence module (RCM) and a sample category confidence module (CCM) to exploit the correlation between these two tasks. The RCM provides knowledge from the probability of plaque regions to the classification task, while the CCM is designed to learn the categorical sample weight for the segmentation task. A total of 1270 2D ultrasound images of carotid plaques were collected from Zhongnan Hospital (Wuhan, China) for our experiments. The results showed that the proposed method can improve both segmentation and classification performance compared to existing single-task networks (i.e., SegNet, Deeplabv3+, UNet++, EfficientNet, Res2Net, RepVGG, DPN) and multi-task algorithms (i.e., HRNet, MTANet), with an accuracy of 85.82% for classification and a Dice-similarity-coefficient of 84.92% for segmentation. In the ablation study, the results demonstrated that both the designed RCM and CCM were beneficial in improving the network's performance. Therefore, we believe that the proposed method could be useful for carotid plaque analysis in clinical trials and practice.
HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development (2017)

Oriented cell division is one mechanism progenitor cells use during development and to maintain tissue homeostasis. Common to most cell types is the asymmetric establishment and regulation of cortical NuMA-dynein complexes that position the mitotic spindle. Here, we discover that HMMR acts at centrosomes in a PLK1-dependent pathway that locates active Ran and modulates the cortical localization of NuMA-dynein complexes to correct mispositioned spindles. This pathway was discovered through the creation and analysis of <i>Hmmr</i>-knockout mice, which suffer neonatal lethality with defective neural development and pleiotropic phenotypes in multiple tissues. HMMR over-expression in immortalized cancer cells induces phenotypes consistent with an increase in active Ran including defects in spindle orientation. These data identify an essential role for HMMR in the PLK1-dependent regulatory pathway that orients progenitor cell division and supports neural development.
Comparison of nonlinear filters for the estimation of parametrized spatial field by robotic sampling (2011)

The use of robotics in distributed monitoring applications requires wireless sensors that are deployed efficiently with an awareness of the information gain, communication constraints, resource allocation and coordination, and energy utilization. In this paper, we address the estimation of a parameterized spatial field distribution with a group of mobile robots sampling adaptively and using a statistically-aware algorithm. The proposed work investigates the use of different nonlinear filters, such as the Extended Kalman Filter (EKF) and some variants of it, and the Unscented Kalman Filter (UKF), both using adaptive sampling, so as to improve the speed and accuracy of the overall field distribution estimation scheme. The results from an extensive simulation work show that different variants of the standard EKF and the standard UKF can be used to improve the accuracy of field estimate and the main objective of this paper is to seek a practical trade-off between the desired field estimation accuracy and the computational load needed for this purpose.
Magnetorheology of Carbonyl-Iron Suspensions With Submicron-Sized Filler (2004)

We added novel submicron-sized particles into carbonyl-iron (CI) suspension to improve the sedimentation problem. The added string-like graphite nano-fiber enhanced the resistance to sedimentation and improved flocculation stability without macroscopically noticeable change in the magnetorheological behaviors. This gap-filling submicron-sized particle between /spl mu/m-sized CI spheres reduced the physical contact of CI particles, and reduced the caking behavior. These systems with and without additives were investigated and compared via a rotational rheometer by accurately controlling the magnetic field strengths.
Mass Spectral Evidence That Small Changes in Composition Caused by Oxidative Aging Processes Alter Aerosol CCN Properties (2007)

Oxidative processing (i.e., "aging") of organic aerosol particles in the troposphere affects their cloud condensation nuclei (CCN) activity, yet the chemical mechanisms remain poorly understood. In this study, oleic acid aerosol particles were reacted with ozone while particle chemical composition and CCN activity were simultaneously monitored. The CCN activated fraction at 0.66 +/- 0.06% supersaturation was zero for 200 nm mobility diameter particles exposed to 565 to 8320 ppmv O3 for less than 30 s. For greater exposure times, however, the particles became CCN active. The corresponding chemical change shown in the particle mass spectra was the oxidation of aldehyde groups to form carboxylic acid groups. Specifically, 9-oxononanoic acid was oxidized to azelaic acid, although the azelaic acid remained a minor component, comprising 3-5% of the mass in the CCN-inactive particles compared to 4-6% in the CCN-active particles. Similarly, the aldehyde groups of alpha-acyloxyalkylhydroperoxide (AAHP) products were also oxidized to carboxylic acid groups. On a mass basis, this conversion was at least as important as the increased azelaic acid yield. Analysis of our results with Köhler theory suggests that an increase in the water-soluble material brought about by the aldehyde-to-carboxylic acid conversion is an insufficient explanation for the increased CCN activity. An increased concentration of surface-active species, which decreases the surface tension of the aqueous droplet during activation, is an interpretation consistent with the chemical composition observations and Köhler theory. These results suggest that small changes in particle chemical composition caused by oxidation could increase the CCN activity of tropospheric aerosol particles during their atmospheric residence time.
No clicks, no problem (2011)

Understanding how people interact with search engines is important in improving search quality. Web search engines typically analyze queries and clicked results, but these actions provide limited signals regarding search interaction. Laboratory studies often use richer methods such as gaze tracking, but this is impractical at Web scale. In this paper, we examine mouse cursor behavior on search engine results pages (SERPs), including not only clicks but also cursor movements and hovers over different page regions. We: (i) report an eye-tracking study showing that cursor position is closely related to eye gaze, especially on SERPs; (ii) present a scalable approach to capture cursor movements, and an analysis of search result examination behavior evident in these large-scale cursor data; and (iii) describe two applications (estimating search result relevance and distinguishing good from bad abandonment) that demonstrate the value of capturing cursor data. Our findings help us better understand how searchers use cursors on SERPs and can help design more effective search systems. Our scalable cursor tracking method may also be useful in non-search settings.
Monosaccharidic mimetics of the sialyl LewisX tetrasaccharide based on 2,7-dihydroxynaphthalene (2012)

A potential monosaccharidic mimetic of the sialyl Lewis X tetrasaccharide (sLe X ) was identified based on an in silico docking study using the crystal structure of an E-selectin-sLe X complex. The chemical synthesis of the mimetic in an ortho-selective C-glycosylation is described. This compound and two close analogues were evaluated in a cell-based selectin binding assay where none of the tested mimetics showed an IC50 below 1mM. This result can be explained by an unexpected 1 C4 conformation of the mannosyl residue which precludes the required binding of the Ca 2+ -ion in E-selectin.
A Comprehensive Analysis of E-Government Adoption in the German Household (2013)

Much of the prior research on IS adoption recognizes that cultural characteristics of the nations influence their adoption behaviors significantly. In the context of e-government, more empirical research is necessary to understand the adoption behaviors of different nations. Our research focuses on understanding the antecedents of e-government adoption in the German household, which has not been adequately addressed to date. Based on the findings of two representative cross-sectional studies, we derived a comprehensive research model and tested it with 1,000 users in the German household on the specific example of e-filing. While the factors of data protection and security were mentioned as crucial in the descriptive studies, the explanatory analysis with LISREL revealed that compatibility is the main antecedent of e-filing adoption in the German nation, followed by relative advantage and perceived risk. Implications for practice and future research are discussed.
Light trapping in thin film solar cells with sub-wavelength photonic crystal patterns (2012)

In this paper we investigate light-trapping in thin film crystalline silicon (c-Si) solar cells with shallow photonic crystal (PhC) front patterns. Coupling of light to the quasi-guided optical modes of the structures becomes a dominant feature when the thickness approaches the wavelength scale. Simple 1D and 2D patterns are investigated using a scattering matrix approach, and best results are compared with the Lambertian limit to light trapping. We show that light trapping can be enhanced by adding a controlled amount of disorder inside the PhC unit cell. We present some preliminary results about a Gaussian size-disorder in 1D structures, and we conclude that an advanced light-trapping design should rely on both order and disorder to maximize the absorption of sunlight.
Holographic video computation and display using Holo-Chidi (2003)

The <i>Journal of Electronic Imaging</i> (JEI), copublished bimonthly with the Society for Imaging Science and Technology, publishes peer-reviewed papers that cover research and applications in all areas of electronic imaging science and technology.
The [NH3Cl]+ Ion (2004)

Stable! The first stable salts containing a simple, inorganic cation with an NCl bond are prepared (see picture). They are [NH3Cl]+[BF4]−, [NH3Cl]+[AsF6]−, and [NH3Cl]+[SbF6]− and can be safely prepared from (Me3Si)2NCl in mixtures of HF and the corresponding Lewis acids and could be used as storable generators for monochloramine gas.
CONTROL OF QUANTUM STATES BY DECOHERENCE (2006)

We propose a new technique to control quantum states by exploiting the decoherence due to the coupling with environment.With this technique we can get any target state, in a stable way and in an exponentially small time, as a stationary state of a semigroup (master equation) canonically derived from a microscopic Hamiltonian model.The stationary state of the system depends (i) on the interaction with the environment; (ii) on the initial state of the environment and it "inherits" some properties of it in a sense that will be explained in sec.5 of the present paper.Moreover this is true not only for by thermal or vacuum environments but also for more general non-equilibrium environments.We prove that, by appropriately choosing this control parametes (interaction system-environment, initial environment state) one can drive the system to an arbitrary preassigned quantum state.
Echocardiographic Predictors of Long‐Term Survival in Patients Undergoing Cardiac Resynchronization Therapy: What Is the Optimal Metric? (2017)

Changes in LVESV and LVEF are better predictors of long-term outcome following CRT compared to changes in LVEDV. Adding an assessment of LVEF to reduction in LVESV ≥ 10% provided the best overall definition for RVR in predicting CRT outcomes.
Response to Recurrent Selection for Yield in Soybeans1 (1982)

The objectives of our research were to evaluate response to recurrent selection for seed yield in a soybean [ Glycine max (L.) Merrill] population and to assess the effect of selection on other agronomic characters. Forty high‐yielding lines and cultivars of Maturity Groups 0 to IV were intermated three generations without selection to form the population AP6. The parents of the cycle 1 population were identified by testing 300 F 3 ‐derived lines of the cycle 0 population, subdividing the 300 lines into three sets of 100 by maturity, and selecting the 10 early, midseason, and late lines with the highest yields. The 30 parents were recombined in a diallel without reciprocals, and 300 F 4 ‐derived lines of the cycle 1 population were tested for yield. The 300 lines were subdivided into three sets of 100 by maturity, and the 10 lines with the highest yields from the three maturity classes were chosen as the parents of cycle 2. The 10 parents of each maturity were mated in separate diallels, 100 F 4 ‐derived lines for each maturity were tested for yield, and the 10 lines with the highest yields of each maturity were chosen as parents of cycle 3. Each cycle of selection required 2 years. Response to selection was evaluated by testing the individual parents of cycles 0 to 3 and a composite of the parents of cycles 1 to 3 as three maturity sets in six Iowa environments during 1979 and 1980. The response to selection for yield was similar when evaluated as the mean performance of individual parents or as a composite of the parents. There was a significant linear increase in yield of 120 ± 10 kg/ha per cycle for the mean of early parents and 24 ±9 kg/ha per cycle for the late, but no significant change in yield for the mean of midseason (‐ 14± kg/ha) parents. Yield of the best parent in cycle 3 was not significantly better than the yield of the best parent of cycle 0 for any maturity set. There was no consistent change in maturity, lodging, height, seed weight and protein and oil percentage caused by the selection for yield.
Acadesine, an adenosine-regulating agent with the potential for widespread indications (2008)

This review highlights that, although limited to intravenous application, acadesine is a potentially viable therapy for ischaemic reperfusion injury following coronary artery bypass surgery. Further studies are required to determine the efficacy of acadesine for other ischaemic indications, including during percutaneous transluminal coronary angioplasty for acute myocardial infarction.
The Seventeenth International Conference on Automated Planning and Scheduling (ICAPS‐07) (2008)

The Seventeenth International Conference on Automated Planning and Scheduling (ICAPS‐07) was held in Providence, Rhode Island, in September 2007. It covered the latest theoretical and practical advances in planning and scheduling. The conference was collocated with the Thirteenth International Conference on Principles and Practice of Constraint Programming (CP‐07). The program consisted of tutorials, workshops, system demonstrations, a doctoral consortium, and three days of technical presentations mostly in parallel sessions. ICAPS‐07 also hosted the second edition of the International Competition on Knowledge Engineering for Planning and Scheduling. This report describes the conference in more detail.
Crustal structure and surface-wave dispersion in Africa* (1956)

Research Article| April 01, 1956 Crustal structure and surface-wave dispersion in Africa* Frank Press; Frank Press Lamont Geological Observatory (Columbia University) Search for other works by this author on: GSW Google Scholar Maurice Ewing; Maurice Ewing Lamont Geological Observatory (Columbia University) Search for other works by this author on: GSW Google Scholar Jack Oliver Jack Oliver Lamont Geological Observatory (Columbia University) Search for other works by this author on: GSW Google Scholar Author and Article Information Frank Press Lamont Geological Observatory (Columbia University) Maurice Ewing Lamont Geological Observatory (Columbia University) Jack Oliver Lamont Geological Observatory (Columbia University) Publisher: Seismological Society of America First Online: 03 Mar 2017 Online Issn: 1943-3573 Print Issn: 0037-1106 Copyright © 1956, by the Seismological Society of America Bulletin of the Seismological Society of America (1956) 46 (2): 97–103. https://doi.org/10.1785/BSSA0460020097 Article history First Online: 03 Mar 2017 Cite View This Citation Add to Citation Manager Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Get Permissions Search Site Citation Frank Press, Maurice Ewing, Jack Oliver; Crustal structure and surface-wave dispersion in Africa. Bulletin of the Seismological Society of America 1956;; 46 (2): 97–103. doi: https://doi.org/10.1785/BSSA0460020097 Download citation file: Ris (Zotero) Refmanager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentBy SocietyBulletin of the Seismological Society of America Search Advanced Search This content is PDF only. Please click on the PDF icon to access. First Page Preview Close Modal You do not have access to this content, please speak to your institutional administrator if you feel you should have access.
Therapeutic Drug Monitoring of Gentamicin Using an Artificial Neural Network (1996)

Clinical Pharmacology & Therapeutics (1996) 59, 214–214; doi: 10.1038/sj.clpt.1996.354
The first reported generation of human induced pluripotent stem cells (iPS cells) and iPS cell-derived cardiomyocytes in the Netherlands. (2010)

One of the recent breakthroughs in stem cell research has been the reprogramming of human somatic cells to an embryonic stem cell (ESC)-like state (induced pluripotent stem cells, iPS cells). Similar to ESCs, iPS cells can differentiate into derivatives of the three germ layers, for example cardiomyocytes, pancreatic cells or neurons. This technique offers a new approach to investigating disease pathogenesis and to the development of novel therapies. It may now be possible to generate iPS cells from somatic cells of patients who suffer from vascular genetic diseases, such as hereditary haemorrhagic telangiectasia (HHT). The iPS cells will have a similar genotype to that of the patient and can be differentiated in vitro into the cell type(s) that are affected in the patient. Thus they will serve as excellent models for a better understanding of mechanisms underlying the disease. This, together with the ability to test new drugs, could potentially lead to novel therapeutic concepts in the near future. Here we report the first derivation of three human iPS cell lines from two healthy individuals and one HHT patient in the Netherlands. The iPS cells resembled ESCs in morphology and expressed typical ESC markers. In vitro, iPS cells could be differentiated into cells of the three germ layers, including beating cardiomyocytes and vascular cells. With this technique it will be possible to establish human cardiovascular disease models from patient biopsies provided by the principal hospitals in the Netherlands. (Neth Heart J 2010;18:51-4.).
Chemical structure and sweet taste of isocoumarin and related compounds. VIII. (1977)

&lt;p&gt;Model-based languages such as MATLAB/Simulink play an essential role in the model-driven development of software systems. During their development, these systems can be subject to modification numerous times. For large-scale systems, to manually identify performed modifications is infeasible. However, their precise identification and subsequent validation is essential for the evolution of model-based systems. If not fully identified, modifications may cause unaccountable behavior as the system evolves and their redress can significantly delay the entire development process. In this paper, we propose a fully automated technique called Reverse Signal Propagation Analysis, which identifies and clusters variations within evolving MATLAB/Simulink models. With each cluster representing a clearly delimitable variation point between models, we allow model engineers not only to specifically focus on single variations, but by using their domain knowledge, to also relate and verify them. By identifying variation points, we assist model engineers in validating the respective parts and reduce the risk of improper system behavior as the system evolves. To assess the applicability of our technique, we present a feasibility study with real-world models from the automotive domain and show our technique to be very fast and highly precise.&lt;/p&gt;
Mobile AR4ALL (2002)

The AR-PDA project develops a framework that allows the use of mobile AR applications for the consumer market. Adapting existing technologies for PDAs (personal digital assistants), high speed wireless computing, computer graphics and computer vision, AR services will be provided at low costs. We discuss the suitability of mobile devices for AR, and address problems of wireless network transmissions and latencies. We present a first running prototype of a wireless PDA with AR features demonstrating a proof-of-concept for a mobile AR system that addresses the consumer market.