gebhart/patrepeval huggingface dataset:
Synchrotron x-ray scattering study of thin epitaxial Pr2O3 films on Si(001) (2006)

We investigate the structural and interfacial properties of thin Pr2O3 films on Si(001) substrates grown by molecular beam epitaxy using synchrotron grazing incidence x-ray diffraction and reflectivity measurements in ultrahigh vacuum. The epitaxial films consist of two orthogonal [101]-oriented cubic domains, with equal proportion. The average in-plane domain sizes are larger than the film thickness. Scans along crystal truncation rods confirm the cubic Mn2O3 structure of the epitaxial layer. A small amount of hexagonal Pr2O3 is found in thin films. Its fraction increases with increasing layer thickness indicating that it is not confined to the interface. Reflectivity measurements reveal an additional layer at the Pr2O3∕Si(001) interface, which is extended by in situ annealing. Transmission electron microscopy of the samples confirms the structural properties of the films found by the x-ray measurements and shows that the interfacial layers are nonuniform with a coexistence of crystalline and amorphous regions.
Synthesis, Characterization, and DNA‐Binding and ‐Cleavage Properties of Dinuclear CuIISalophen/Salen Complexes (2011)

Dinuclear Cu(II) complexes, [Cu(2) (salophen)(2) ] (1) and [Cu(2) (salen)(2) ] (2), with Schiff bases derived from salicylaldehyde and o-phenylenediamine (ophen) or ethylenediamine (en) were synthesized and characterized. They exhibit square-planar geometry with CuN(2) O(2) coordination, where the dianionic Schiff base acts as a tetradentate N(2) O(2) donor ligand. Calf thymus (CT)-DNA Binding studies revealed that the complexes possess good binding propensities (K(b) =3.13×10(5) for 1 and K(b) =2.99×10(5) M(-1) for 2). They show good DNA-cleavage abilities under oxidative and hydrolytic conditions. Complex 1 binds and cleaves DNA more efficiently as compared to 2 due to the presence of an extended aromatic phenyl ring which might be involved in an additional stacking interaction with DNA bases. From the kinetic experiments, hydrolytic DNA-cleavage rate constants were determined as 1.54 for 1 and 0.72 h(-1) for 2. The nuclease activities of 1 and 2 are significant, giving rise to (2.03-2.88)×10(7) -fold rate enhancement compared to non-catalyzed DNA cleavage.
Supplementary Table 1 from Upregulation of miR-196a and <i>HOTAIR</i> Drive Malignant Character in Gastrointestinal Stromal Tumors (2023)

&lt;p&gt;XLS file - 25K, Summary of GIST samples used in the miRNA microarray analysis&lt;/p&gt;
Locus‐specific detection of HLA‐DQ and ‐DR antigens by antibodies against synthetic N‐terminal octapeptides of the β chain (1985)

Antibodies against synthetic peptides representing the class-II antigen HLA-DR and -DQ beta chain N-terminal sequences were prepared in rabbits. The two octapeptides only share two amino acids and enzyme-linked immuno-assays showed the antisera only to bind to its own antigen. Both peptide antisera detected a 29 kDa component in immunoblots of Raji and AL-34 cell plasma membrane proteins separated by SDS gel electrophoresis. The binding of either N-terminal peptide antiserum was selectively inhibited only by the peptide used as antigen. Indirect immunofluorescence analysis by flow cytofluorometry showed specific surface immunofluorescence in 1:100-1:1000 dilutions in lymphoblastoid and blood mononucleated cells. In the latter the binding was primarily confined to monocytes and a subpopulation of lymphocytes. It is concluded that locus-specific immunological reagents to distinguish between beta chains of HLA-DR and -DQ have been prepared by the preparation by the production of antibodies against the N-terminal sequences of each polypeptide.
Film growth arising from the deposition of Au onto ani-Al–Pd–Mn quasicrystal: a medium energy ion scattering study (2006)

The room temperature deposition of 7ML of Au onto the fivefold symmetric surface of icosahedral Al-Pd-Mn leads to the formation of a several monolayers thick Au-Al alloy film. An AlAu film with 1:1 stoichiometry is formed, which shows no evidence of ordered structure, being either amorphous or polycrystalline. Annealing to 325 °C causes more Al to diffuse into the film, producing Al 2Au but still with no indication of structure. Experiments using 0.5ML of pre-deposited In demonstrated a surfactant effect as the In 'floated' on the surface during growth and produced a reduction in film roughness. However, contrary to previous findings the film was still either amorphous or polycrystalline, with no evidence of quasi-crystalline or aperiodic structure. Experiments were also conducted using smaller doses of Au to look for the formation of an epitaxial layer and, if formed, determine the registry with the substrate. However, no change in the Pd blocking curves for the surface could be seen, suggesting that the Au does not adsorb in well defined sites. This result is not surprising when considering that even for these low doses Al is drawn into the film, changing the composition and probably the structure of the topmost layers of the substrate, so that the potential adsorption sites on the clean surface may no longer exist.
Supplementary figures with legends from CCR5<sup>+</sup> Myeloid-Derived Suppressor Cells Are Enriched and Activated in Melanoma Lesions (2023)

&lt;p&gt;Fig.S1:CCR5 ligands are enriched in mouse melanoma lesions and induce the migration of CD11b Gr1 cells. Fig.S2:Immunosuppressivephenotype of CCR5 MDSC in tumor bearing mice. Fig.S3:Induction of CCR5 expression and immunosuppressive molecules by inflammatory factors. Fig.S4:Immunosuppressivepattern of CCR5 MDSC from melanoma patients. Fig.S5:Increased production of immunosuppressive molecules by CCR5 MDSC in melanoma patients.&lt;/p&gt;
Robustness to mechanical perturbations of centre-launching technique in multi-mode fibres for transparent optical interconnects (2013)

In this paper we exploit the centre-launching technique to allow single-mode propagation in multi-mode fibres and to guarantee full transparency to the transmitted optical signal for applications in board-to-board and data server interconnects. We show that this technique is robust to mechanical perturbations up to about 1 kHz, demonstrating that vibrations do not affect the transmission performances. Different experimental configurations are tested in order to confirm that only the fundamental mode propagates, without excitation of higher-order modes.
CMT: An Equivalent Circuit Modeling Tool for Ultrasonic Transducer (2008)

The equivalent circuit modeling of sensor can simplify the sensing problem as a pure electronics problem. As one kind of widely used sensor, there are also numerous equivalent circuit models for the ultrasonic transducer. However, the parameters of equivalent circuit of transducer are inconvenient for a common engineer to calculate, since so many variables, constants and formulae are involved in. Motivated by this, a toolkit named CMT is proposed. When given the details about the transducer in use and the requirement about the equivalent circuit, this tool will generate the SPICE file for the circuit. Such a SPICE file can be subsequently used in a circuit simulating software, for test of transducer properties and for the development of sensing system. For a better use, some optimizations are adopted, to minimize the working load of user in data management, and to speedup the calculation of the circuit parameters.
HPLC Analysis of Novel Anti-Cancer Agents-Illudins and Their Analogs (1993)

Abstract High performance liquid chromatography combined with liquid extraction and solid-phase extraction were used for determining the serum concentration of new anticancer drugs. Extraction recoveries were evaluated for wide range of concentrations in serum. Adsorption and reversed-phase chromatographic modes were tested for the separation and drugs determination in model mixtures and actual clinical samples. The HPLC assay developed was applied for farmacokinetic Studies of acylfulvene in dog and rats.
Direct Gear Design for Spur and Helical Involute Gears (2002)

analysis and design of spur and helical involute gears. Introduction Modern gear design is generally based on standard tools. This makes gear design quite simple (almost like selecting fasteners), economical, and available for everyone, reducing tooling expenses and inventory. At the same time, it is well known that universal standard tools provide gears with less than optimum performance and— in some cases—do not allow for finding acceptable gear solutions. Application specifics, including low noise and vibration, high density of power transmission (lighter weight, smaller size) and others, require gears with nonstandard parameters. That’s why, for example, aviation gear transmissions use tool profiles with custom proportions, such as pressure angle, addendum, and whole depth. The following considerations make application of nonstandard gears suitable and cost-efficient: • CNC cutting machines and CMM gear inspection equipment make production of nonstandard gears as easy as production of standard ones. • Cost of the custom cutting tool is not much higher than that of the cutting tool for standard gears and can be amortized if production quantity is large enough. • The custom gear performance advantage makes a product more competitive and justifies larger tooling inventory, especially in mass production. • Gear grinding is adaptable to custom tooth shapes. • Metal and plastic gear molding cost largely does not depend on tooth shape. This article presents the direct gear design method, which separates gear geometry definition from tool selection, to achieve the best possible performance for a particular product and application. The direct design approach that is commonly used for most parts of mechanisms and machines (for example, cams, linkages, compressor or turbine blades, etc.) determines their profiles according to the operating conditions and desired performance. Ancient engineers used the same Direct Gear Design for Spur and Helical Involute Gears
Role of Complement in Multi-Organ Dysfunction Syndrome (2006)

In critically ill humans with manifestation of a systemic inflammatory response syndrome (SIRS), the onset of multi-organ dysfunction syndrome (MODS) is a well known complication that is associated with a high mortality rate. Clinical and experimental evidence increasingly suggests, a disturbance of innate immunity, linked to the uncontrolled activation of the complement system, which results in excessive generation of anaphylatoxins (C3a, C4a, C5a) and impairment of the cellular defense system (especially neutrophil-dysfunction). Such changes may play a central role in the development of MODS. In experimentally-induced MODS, complement depletion, absence of C5 (C5-/- mice), specific blockade of the complement system by C1-inhibitor (C1-INH), soluble complement receptor-1 (sCR-1), blockade of C5a or its C5a receptor (C5aR), all appear to prevent the development of MODS and improve survival. Therefore, irrespective of the initial insult, early inhibition of excessive complement activation during SIRS might be a promising approach for preventing development of the deathly spiral of MODS
Maximum differentiation (MAD) competition: A methodology for comparing computational models of perceptual quantities (2008)

We propose an efficient methodology for comparing computational models of a perceptually discriminable quantity. Rather than comparing model responses to subjective responses on a set of pre-selected stimuli, the stimuli are computer-synthesized so as to optimally distinguish the models. Specifically, given two computational models that take a stimulus as an input and predict a perceptually discriminable quantity, we first synthesize a pair of stimuli that maximize/minimize the response of one model while holding the other fixed. We then repeat this procedure, but with the roles of the two models reversed. Subjective testing on pairs of such synthesized stimuli provides a strong indication of the relative strengths and weaknesses of the two models. Specifically, the model whose extremal stimulus pairs are easier for subjects to discriminate is the better model. Moreover, careful study of the synthesized stimuli may suggest potential ways to improve a model or to combine aspects of multiple models. We demonstrate the methodology for two example perceptual quantities: contrast and image quality.
Stability and function of interdomain linker variants of glusoamylase 1 from Aspergillus niger (2001)

International audience
Audiovisuel d’entreprise en Aquitaine : la mystique et le rationnel (1992)

Les audiovisuels d’entreprise aquitains utilisent deux procédés spécifiques : l’association et la caractérisation. En agissant aux différents niveaux de la structure filmique ces deux procédés concourent à forger un discours de mobilisation propre à l’intention promotionnelle. La forme et la matière de ces produits, construits de façon rationnelle, permettent de parler de l’émergence d’un genre.Les modes de réalisation et d’exploitation relèvent par contre des pratiques intuitives. La commande est souvent passée à l’occasion, les cibles ne sont pas toujours bien connues. Ces documents existent ; ils sont donc satisfaisants. C’est la mystique de l’image.
Channel Selection Algorithm for Cognitive Radio Networks with Heavy-Tailed Idle Times (2016)

We consider a multichannel Cognitive Radio Network (CRN), where secondary users sequentially sense channels for opportunistic spectrum access. In this scenario, the Channel Selection Algorithm (CSA) allows secondary users to find a vacant channel with the minimal number of channel switches. Most of the existing CSA literature assumes exponential ON-OFF time distribution for primary users (PU) channel occupancy pattern. This exponential assumption might be helpful to get performance bounds; but not useful to evaluate the performance of CSA under realistic conditions. An in-depth analysis of independent spectrum measurement traces reveals that wireless channels have typically heavy-tailed PU OFF times. In this paper, we propose an extension to the Predictive CSA framework and its generalization for heavy tailed PU OFF time distribution, which represents realistic scenarios. In particular, we calculate the probability of channel being idle for hyper-exponential OFF times to use in CSA. We implement our proposed CSA framework in a wireless test-bed and comprehensively evaluate its performance by recreating the realistic PU channel occupancy patterns. The proposed CSA shows significant reduction in channel switches and energy consumption as compared to Predictive CSA which always assumes exponential PU ON-OFF times.Through our work, we show the impact of the PU channel occupancy pattern on the performance of CSA in multichannel CRN.
VII. DİN PSİKOLOJİSİ ANABİLİM DALLARI KOORDİNASYON TOPLANTISI (İZMİR) DİN PSİKOLOJİSİNİN DİN HİZMETLERİNE KATKILARI BAĞLAMINDA YENİLİKÇİ (İNOVATİF) ARAYIŞLAR SEMPOZYUMU (2016)

Din hizmetlerinin yeni bir kolu olarak değerlendirebileceğimiz ve son zamanlarda çeşitli platformlarda tartışma konusu olan manevi bakı m (dinî dan ışmanlık, manevi rehberlik, maneviyat psikolojisi, manevi sosyal hizmet, manevi psikolojik danışmanlık vb.) kavramını ve bununla ilgili ortaya çıkan yeni durumları, ilgili anabilim dallarının yaklaşımları çerçevesinde ele almak bu sempozyumun en temel amacı olarak belirlenmiştir. Ayrıca Din-İnsan ilişkisinden hareketle dinî danışmanlığın tarihsel gelişimi, günümüzde dinî danışmanlığa y üklenen anlam ve bu konuda yapılan tartışmalar, Diyanet İşleri Başkanlığının dinî rehberlik başlığı altında yürütülecek olan faaliyet ve uygulamalardan beklentileri ve bu alanda ortaya çıkan çeşitli problemlerin ele alınması amaçlanmıştır. Bu çerç evede sempozyum, Diyanet İşleri Başkanlığının asli görevi olan din hizmetlerini, Psikoloji, Sosyal Hizmet, Dinler Tarihi, Kelam ve Din Psikolojisi penceresinden değerlendirerek bireysel, sosyal ve kurumsal açıdan yeni yaklaşım ve katkıların ortaya çıkmasına yardımcı olmayı hedeflem iştir.
High Complete Response in Advanced Nasopharyngeal Carcinoma With Bleomycin, Epirubicin, and Cisplatin Before Radiotherapy (1990)

Undifferentiated carcinoma of nasopharyngeal type (UCNT) is a geographically endemic, Epstein-Barr virus-related carcinoma of epidermoid origin with reported 5-year survival rates of 15%-40% when treated with radiotherapy alone. Although UCNT can be well controlled locally by radiation therapy, in advanced nodal stage N3 [International Union Against Cancer-American Joint Committee on Cancer (UICC-AJCC, 1987)] the survival rate is below 20%, primarily because of metastatic spread in 80% of the fatalities. We report a pilot study of 41 patients with nonmetastatic, locoregionally advanced disease (85% of the patients had a nodal status greater than or equal to N2C-N3; 43% had T4 primaries), during which we used a combination of 100 mg of cisplatin/m2 on day 1, 15 mg of bleomycin by intravenous push and 12 mg/m2 by continuous infusion on days 1-5, and 70 mg of epirubicin/m2 on day 1 every 21 days for three cycles before definitive radiation therapy with 70 Gy for 7 weeks. Twenty-seven of 41 patients (66%; 95% confidence interval = 52.5%-80.5%) achieved a clinical complete response, and 40 of 41 (98%) had a major objective response after chemotherapy. Two deaths were treatment related, but side effects were moderate, and the overall treatment sequence was feasible. At the end of radiation therapy, all 39 assessable patients were in complete response, with a median follow-up of 21+ months (greater than 10-greater than 31); 33 (80%) patients had no evidence of disease. We believe that such a complete response rate in a high-volume disease with the use of combined modality treatment indicates a therapeutic gain in UCNT. Researchers performing a multicenter international controlled trial will test this hypothesis and compare local control, disease-free, and overall survival of the therapeutic sequence presented here with radiotherapy alone.
Edwin G. Krebs (1918–2009) (2010)

Defining how protein phosphorylation is regulated led to an explosion of knowledge about most cellular processes.
Privacy-preserving management of transactions' receipts for mobile environments (2009)

Users increasingly use their mobile devices for electronic transactions to store related information, such as digital receipts. However, such information can be target of several attacks. There are some security issues related to M-commerce: the loss or theft of mobile devices results in a exposure of transaction information; transaction receipts that are send over WI-FI or 3G networks can be easily intercepted; transaction receipts can also be captured via Bluetooth connections without the user's consent; and mobile viruses, worms and Trojan horses can access the transaction information stored on mobile devices if this information is not protected by passwords or PIN numbers. Therefore, assuring privacy and security of transactions' information, as well as of any sensitive information stored on mobile devices is crucial. In this paper, we propose a privacy-preserving approach to manage electronic transaction receipts on mobile devices. The approach is based on the notion of transaction receipts issued by service providers upon a successful transaction and combines Pedersen commitment and Zero Knowledge Proof of Knowledge (ZKPK) techniques and Oblivious Commitment-Based Envelope (OCBE) protocols. We have developed a version of such protocol for Near Field Communication (NFC) enabled cellular phones.
Off-line cursive script word recognition (1989)

Cursive script word recognition is the problem of transforming a word from the iconic form of cursive writing to its symbolic form. Several component processes of a recognition system for isolated offline cursive script words are described. A word image is transformed through a hierarchy of representation levels: points, contours, features, letters, and words. A unique feature representation is generated bottom-up from the image using statistical dependences between letters and features. Ratings for partially formed words are computed using a stack algorithm and a lexicon represented as a trie. Several novel techniques for low- and intermediate-level processing for cursive script are described, including heuristics for reference line finding, letter segmentation based on detecting local minima along the lower contour and areas with low vertical profiles, simultaneous encoding of contours and their topological relationships, extracting features, and finding shape-oriented events. Experiments demonstrating the performance of the system are also described.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Text Classification Using the N-Gram Graph Representation Model Over High Frequency Data Streams (2018)

A prominent challenge in our information age is the classification over high frequency data streams. In this research, we propose an innovative and high-accurate text stream classification model that is designed in an elastic distributed way and is capable to service text load with fluctuated frequency. In this classification model, text is represented as N-Gram Graphs and the classification process takes place using text pre-processing, graph similarity and feature classification techniques following the supervised machine learning approach. The work involves the analysis of many variations of the proposed model and its parameters, such as various representations of text as N-Gram Graphs, graph comparisons metrics and classification methods in order to conclude to the most accurate setup. To deal with the scalability, the availability and the timely response in case of high frequency text we employ the Beam programming model. Using the Beam programming model the classification process occurs as a sequence of distinct tasks and facilitates the distributed implementation of the most computational demanding tasks of the inference stage. The proposed model and the various parameters that constitute it are evaluated experimentally and the high frequency stream emulated using two public datasets (20NewsGroup and Reuters-21578) that are commonly used in the literature for text classification.
Self-Assembled Peptide-Carbon Nitride Hydrogel as a Light-Responsive Scaffold Material (2017)

Peptide self-assembly is a facile route to the development of bioorganic hybrid materials that have sophisticated nanostructures toward diverse applications. Here, we report the synthesis of self-assembled peptide (Fmoc-diphenylalanine, Fmoc-FF)/graphitic carbon nitride (g-C<sub>3</sub>N<sub>4</sub>) hydrogels for light harvesting and biomimetic photosynthesis through noncovalent interactions between aromatic rings in Fmoc-FF nanofibers and tris-s-triazine in g-C<sub>3</sub>N<sub>4</sub> nanosheets. According to our analysis, the photocurrent density of the Fmoc-FF/g-C<sub>3</sub>N<sub>4</sub> hydrogel was 1.8× higher (0.82 μA cm<sup>-1</sup>) than that of the pristine g-C<sub>3</sub>N<sub>4</sub>. This is attributed to effective exfoliation of g-C<sub>3</sub>N<sub>4</sub> nanosheets in the Fmoc-FF/g-C<sub>3</sub>N<sub>4</sub> network, facilitating photoinduced electron transfers. The Fmoc-FF/g-C<sub>3</sub>N<sub>4</sub> hydrogel reduced NAD<sup>+</sup> to enzymatically active NADH under light illumination at a high rate of 0.130 mol g<sup>-1</sup> h<sup>-1</sup> and drove light-responsive redox biocatalysis. Moreover, the Fmoc-FF/g-C<sub>3</sub>N<sub>4</sub> scaffold could well-encapsulate key photosynthetic components, such as electron mediators, cofactors, and enzymes, without noticeable leakage, while retaining their functions within the hydrogel. The prominent activity of the Fmoc-FF/g-C<sub>3</sub>N<sub>4</sub> hydrogel for biomimetic photosynthesis resulted from the easy transfer of photoexcited electrons from electron donors to NAD<sup>+</sup> via g-C<sub>3</sub>N<sub>4</sub> and electron mediators as well as the hybridization of key photosynthetic components in a confined space of the nanofiber network.