gebhart/patrepeval huggingface dataset:
Object tracking with convolutional neural networks and kernelized correlation filters (2017)

Convolutional neural networks are widely used in object recognition and detection. In recent years, some researchers attempt to apply deep neural networks to visual object tracking. However, deep networks are extremely time-consuming and object tracking is not a classification problem essentially. In this paper, we present an online tracking framework which combines shallow convolutional neural networks with kernelized correlation filters(KCF). Different from offline training, our method successfully gets the convolution kernels by K-means clustering algorithm. Experimental results based on a representative visual tracker benchmark dataset show that the proposed method achieves excellent performance.
Spectral Tuning of White Light Allows for Strong Reduction in Melatonin Suppression without Changing Illumination Level or Color Temperature (2018)

Studies with monochromatic light stimuli have shown that the action spectrum for melatonin suppression exhibits its highest sensitivity at short wavelengths, around 460 to 480 nm. Other studies have demonstrated that filtering out the short wavelengths from white light reduces melatonin suppression. However, this filtering of short wavelengths was generally confounded with reduced light intensity and/or changes in color temperature. Moreover, it changed the appearance from white light to yellow/orange, rendering it unusable for many practical applications. Here, we show that selectively tuning a polychromatic white light spectrum, compensating for the reduction in spectral power between 450 and 500 nm by enhancing power at even shorter wavelengths, can produce greatly different effects on melatonin production, without changes in illuminance or color temperature. On different evenings, 15 participants were exposed to 3 h of white light with either low or high power between 450 and 500 nm, and the effects on salivary melatonin levels and alertness were compared with those during a dim light baseline. Exposure to the spectrum with low power between 450 and 500 nm, but high power at even shorter wavelengths, did not suppress melatonin compared with dim light, despite a large difference in illuminance (175 vs. <5 lux). In contrast, exposure to the spectrum with high power between 450 and 500 nm (also 175 lux) resulted in almost 50% melatonin suppression. For alertness, no significant differences between the 3 conditions were observed. These results open up new opportunities for lighting applications that allow for the use of electrical lighting without disturbance of melatonin production.
Exploring attachment chemistry with FRET in hybrid quantum dot dye-labeled DNA dendrimer composites (2018)

Light harvesting quantum dot-dye-labeled DNA dendrimer structures are assembled yielding end-to-end energy transfer efficiencies approaching 25% over 4 FRET steps.
Xanthates Derived from 1,3‐Dithiane and Its Monosulfoxide; One‐Carbon Radical Equivalents. (2004)

Abstract For Abstract see ChemInform Abstract in Full Text.
Precise oculocentric mapping of TMS-evoked phosphenes (2020)

ABSTRACT Transcranial Magnetic Stimulation (TMS) – evoked phosphenes are oculocentric; their perceived location depends upon eye position. We investigated the accuracy and precision of TMS-evoked phosphene oculocentric mapping and demonstrate that perceived phosphene locations map veridically to eye position, although there are considerable individual differences in the reliability of this mapping. Our results emphasize the need to carefully control eye movements when carrying out phosphene localization studies and suggest that individual differences in the reliability of the reported position of individual phosphenes must be considered.
Optimal pulse compression in long hollow fibers (2011)

The spectral broadening performance of 1 m and 3 m long hollow fibers are compared. The 3 m capillary clearly outperforms the 1 m one in terms of both transmission and achievable spectral broadening. Starting from 1.1 mJ 71 fs pulses at 780 nm, a spectral broadening ratio of 26 was achieved using a single 3 m long argon-filled hollow fiber. After compression the measured pulse duration was 4.5 fs corresponding to a compression ratio of 16 at an energy of 0.42 mJ. Both the pulse duration and the pulse energy were limited by the applied chirped mirrors.
Probabilistic Evolving Meal Detection and Estimation of Meal Total Glucose Appearance (2009)

This novel, extensible meal detection and total glucose appearance estimation method shows the feasibility, relevance, and performance of evolving estimates with explicit uncertainty measures for use in closed-loop control of type 1 diabetes.
CCR Translation for This Article from Dual Targeting of HER2-Positive Cancer with Trastuzumab Emtansine and Pertuzumab: Critical Role for Neuregulin Blockade in Antitumor Response to Combination Therapy (2023)

CCR Translation for This Article from Dual Targeting of HER2-Positive Cancer with Trastuzumab Emtansine and Pertuzumab: Critical Role for Neuregulin Blockade in Antitumor Response to Combination Therapy
AlGaAs tunnel junction for high efficiency multi-junction solar cells: Simulation and measurement of temperature-dependent operation (2009)

AlGaAs tunnel junctions are shown to be well-suited to concentrated photovoltaics where temperatures and current densities can be dramatically higher than for 1-sun flat-panel systems. Detailed comparisons of AlGaAs/AlGaAs tunnel junction experimental measurements over a range of temperatures expected during device operation in concentrator systems are presented. Experimental and simulation results are compared in an effort to decouple the tunnel junction from the overall multi-junction solar cell. The tunnel junction resistance is experimentally studied as a function of the temperature to determine its contribution to overall efficiency of the solar cell. The current-voltage behavior of the isolated TJ shows that as the temperature is increased from 25°C to 85°C, the resistance decreases from ~4.7×10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-4</sup> ¿·cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> to ~0.3×10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-4</sup> ¿·cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> for the operational range of a multi-junction solar cell under concentration.
200. The constituents of natural phenolic resins. Part XVII. A synthesis of l-matairesinol (1940)

R. D. Haworth and F. H. Slinger, J. Chem. Soc., 1940, 1098 DOI: 10.1039/JR9400001098
The regulatory properties of rabbit muscle pyruvate kinase. The influence of effector concentrations (1983)

The initial velocity of the reaction catalysed by rabbit muscle pyruvate kinase was studied as a function of the concentrations of the modifiers phenylalanine and fructose 1,6-bisphosphate under conditions where the relationships between the initial velocities and the concentrations of substrates are non-hyperbolic. It is shown that these data can be represented by the exponential model for a regulatory enzyme.
Spectral and time-resolved studies on ocular structures (2007)

Measurements of endogeous fluorophores open the possibility for evaluation of metabolic state at the eye. For interpretation of 2 - dimensional measurements of time-resolved auto fluorescence in 2 separate spectral ranges at the human eye, comparing measmements were performed on porcine eyes. Determining excitation and emission spectra, attention was drawn of proof of coenzymes NADH and FAD in isolated anatomical structures cornea, aqueous humor, lens, vitreous, neuronal retina, retinal pigment epithelium (RPE), choroid, and sclera. All these structures exhibit auto fluorescence, highest in lens. Excitation at 350 nm results in local fluorescence maxima at 460 nm, corresponding to NADH, in all structures. This short-wave excitation allows metabolic studies only at the anterior eye, because of the limited transmission of the ocular media. During excitation at 446 nm the existence of FAD is expressed by local fluorescence maxima at 530 nm. The composition fluorescence spectra allow no discrimination between single ocular structures. Approximating the dynamic fluorescence by a double exponential function, the shortest lifetimes were detected in RPE and neuronal retina. The histograms of mean lifetime tM cover each other on lens with cornea and also on sclera with choroid. Despite the lifetimes are close between RPE and neuronal retina, the relative contributions Q1 are wide different. The gradient of trend lines in cluster diagrams of amplitudes α2 vs. α1 allows a discrimination of ocular structures.
Heterocyclic compounds from 3,3‐dimercapto‐1‐aryl‐2‐propen‐1‐ones. Note 3. Condensation with N‐methyl‐o‐phenylenediamine and N‐benzyl‐o‐phenylenediamine (1975)

Abstract Two seven‐membered ring compounds and three five‐membered ring compounds were obtained by reaction in hot xylene of 3,3‐dimercapto‐l‐phenyl‐2‐propen‐1‐one (1) with N ‐alkyl‐ o ‐phenylenediamines (2) . Compounds isolated were the 4‐phenyl‐5‐alkyl‐1,5‐dihydro‐2 H ‐1,5‐benzodiazepine‐2‐thiones (3) the 1‐alkyl‐4‐phenyl‐1,3‐dihydro‐2 H ‐1,5‐benzodiazepine‐2‐thiones (4) , the 1‐alkyl‐2‐phenacylbenzimidazoles (5) , the 1‐alkyl‐2‐phenylbenzimidazoles (6) and the 1‐alkyl‐2‐methylbenzimidazoles (7) . The structures of these compounds were elucidated from their chemical reactivity and their nmr and ir spectra.
(De)form and Function: Measuring Cellular Forces with Deformable Materials and Deformable Structures (2020)

The ability for biological cells to produce mechanical forces is important for the development, function, and homeostasis of tissue. The measurement of cellular forces is not a straightforward task because individual cells are microscopic in size and the forces they produce are at the nanonewton scale. Consequently, studies in cell mechanics rely on advanced biomaterials or flexible structures that permit one to infer these forces by the deformation they impart on the material or structure. Herein, the scientific progression on the use of deformable materials and deformable structures to measure cellular forces are reviewed. The findings and insights made possible with these approaches in the field of cell mechanics are summarized.
Cell-mediated immunity in yellow forms of rainbow trout. (2003)

The aim of the present study was to investigate possible pleiotropic effects of the genotypes controlling the palomino and albino coloration on blood phagocyte and lymphocyte activity. The results showed that the wild coloured trout has a higher metabolic and potential killing activity of blood phagocytes, compared to albino and palomino coloured trout. The proliferative response of blood lymphocytes stimulated by ConA or LPS indicated a similar pattern. The results showed that lymphocyte proliferation was statistically significantly higher in wild coloured trout, compared to albino and palomino trout.
Innate Immune Antagonism of Mosquito-Borne Flaviviruses in Humans and Mosquitoes (2021)

Mosquito-borne viruses of the <i>Flavivirus</i> genus (<i>Flaviviridae</i> family) pose an ongoing threat to global public health. For example, dengue, Japanese encephalitis, West Nile, yellow fever, and Zika viruses are transmitted by infected mosquitoes and cause severe and fatal diseases in humans. The means by which mosquito-borne flaviviruses establish persistent infection in mosquitoes and cause disease in humans are complex and depend upon a myriad of virus-host interactions, such as those of the innate immune system, which are the main focus of our review. This review also covers the different strategies utilized by mosquito-borne flaviviruses to antagonize the innate immune response in humans and mosquitoes. Given the lack of antiviral therapeutics for mosquito-borne flaviviruses, improving our understanding of these virus-immune interactions could lead to new antiviral therapies and strategies for developing refractory vectors incapable of transmitting these viruses, and can also provide insights into determinants of viral tropism that influence virus emergence into new species.
Web semántica y ontologías en el procesamiento de la información documental (2007)

The lack of a well defined model of information representation on the web has produced several problems related to processing information. In an effort to resolve these problems, the W3C has proposed the semantic web project. This new scenario offers both possibilities and difficulties for the future. Special attention is given to ontologies, fundamental tools for the representation of knowledge on the semantic web. Finally, the role of library and information professionals is considered in this new context.
FISH Glossary: An Overview of the Fluorescence in Situ Hybridization Technique (2008)

The introduction of FISH (fluorescence in situ hybridization) marked the beginning of a new era for the study of chromosome structure and function. As a combined molecular and cytological approach, the major advantage of this visually appealing technique resides in its unique ability to provide an intermediate degree of resolution between DNA analysis and chromosomal investigations while retaining information at the single-cell level. Used to support large-scale mapping and sequencing efforts related to the human genome project, FISH accuracy and versatility were subsequently capitalized on in biological and medical research, providing a wealth of diverse applications and FISH-based diagnostic assays. The diversification of the original FISH protocol into the impressive number of procedures available these days has been promoted throughout the years by a number of interconnected factors: the improvement in sensitivity, specificity and resolution, together with the advances in the fields of fluorescence microscopy and digital imaging, and the growing availability of genomic and bioinformatic resources. By assembling in a glossary format many of the "acronymed" FISH applications published so far, this review intends to celebrate the ability of FISH to re-invent itself and thus remain at the forefront of biomedical research.
In situ, real-time observation of Al chemical-vapor deposition on SiO2 in an environmental transmission electron microscope (1994)

A technique for in situ observation of chemical-vapor deposition (CVD) is demonstrated. An environmental transmission electron microscope with 3.8 Å resolution was used for real-time, in situ observation of Al CVD onto SiO2 from trimethylamine alane (TMAA). Nominal TMAA pressures from 50 to 400 mTorr and substrate temperatures from 50 to 200 °C were investigated for deposition onto both TiCl4 pretreated and untreated surfaces. For deposition onto untreated surfaces, low nucleation densities and polycrystalline, dendritelike growth were observed for all deposition temperatures with deposition commencing at about 150 °C. Deposition on TiCl4-treated surfaces resulted in polycrystalline films with grain sizes of a few nm and lower-temperature (100 °C) growth.
Radiation sensitivity of leukemic progenitor cells in acute nonlymphocytic leukemia. (1983)

The radiation sensitivity of leukemic progenitor cells in 12 cases of acute nonlymphocytic leukemia was compared with that of normal myeloid progenitor cells (colony-forming units in culture), using in vitro cloning techniques. The D0 value for normal colony-forming units in culture was almost constant (130 +/- 14 rads). On the other hand, marked patient-to-patient variations were observed in the radiosensitivity of leukemic progenitor cells; namely, the D0 values in the present cases ranged from 30 to 210 rads. These variations seemed to be partly due to different cell cycle status and partly due to the intrinsic nature of leukemic progenitor cells. Moreover, in six of seven clinically drug-sensitive cases, the leukemic progenitor cells were proved to be relatively radiosensitive. Similar to in vitro drug sensitivity tests, this test may serve to predict the clinical response to chemoradiotherapy.
Tegumento e profundidade de semeadura na emergência de plântulas e no desenvolvimento do porta-enxerto Trifoliata (2007)

O objetivo deste trabalho foi otimizar a emergência de plântulas e o desenvolvimento do porta-enxerto de citros Trifoliata [Poncirus trifoliata (L.) Raf.], por meio de tratamentos mecânicos do tegumento das sementes e da variação na profundidade de semeadura. O experimento foi realizado no período de junho a outubro de 2004, em casa-de-vegetação com temperatura controlada. A semeadura foi realizada em tubetes de plástico, contendo substrato comercial. Tegumento íntegro, tegumento com orifício no endosperma do lado oposto ao do embrião e sem tegumento foram as formas de tratar as sementes, semeadas em quatro profundidades (0,5; 1,0; 2,0; e 3,0 cm), sendo o experimento instalado em delineamento de blocos ao acaso, em esquema fatorial, com quatro repetições, sendo as unidades experimentais constituídas por 48 tubetes com uma semente cada. Verificou-se que a remoção do tegumento propicia maior porcentagem final de emergência (90%), em relação à realização de um orifício no endosperma (83%) e à manutenção do tegumento (73%). O desenvolvimento dos porta-enxertos é maior quando utilizadas sementes sem tegumento ou com orifício no endosperma. As profundidades de semeadura de 1 e 2 cm são as recomendadas para o porta-enxerto Trifoliata.
Vibration control of a traffic signal pole using a pounding tuned mass damper with viscoelastic materials (II): experimental verification (2013)

In the first part of this paper, the theoretical and simulation analyses have been studied to prove the effectiveness of the pounding tuned mass damper (PTMD) to control the vibration of a traffic signal pole. In order to further verify the control effect of the PTMD, an experimental structure was prepared to test the novel approach in the lab. A horizontal and a vertical steel pipe are used to model the traffic signal pole. An L-shaped beam and a pounding collar covered on the interior with viscoelastic materials are used as the PTMD device. Both free and excited vibration tests were performed with and without PTMD control on the structure. It was found that the damping device was very effective in controlling the vibrations of the structure in both out-plane and in-plane vibrations.
Adsorption of γ‐globulin, a model protein for antibody, on colloidal particles (1991)

The effect of surface properties on the adsorption of bovine gamma-globulin, a model protein for antibody, was studied. Polystyrene latex (PS), hydrophilic copolymer lattices of styrene/2-hydroxyethyl methacrylate [P(S/HEMA)], styrene/ methacrylic acid [P(S/MAA)] and methyl methacrylate/ 2-hydroxyethyl methacrylate [P(MMA/HEMA)], and colloidal silica were used. The adsorption isotherms of gamma-globulin on these colloidal particles were measured as a function of pH and ionic strength. The hydrophilic particles showed low affinities for gamma-globulin at alkaline pH, while PS showed high affinities for gamma-globulin over the whole range of pH and ionic strength. The gamma-globulin adsorption on hydrophilic particles was highly reversible with respect to the pH and ionic strength compared with that on PS. These differences indicate that the dominant driving forces of adsorption are related to the hydrophilicity of particles. The adsorption isotherms of all colloidal particles showed the plateau values, and the order of maximum values of plateau adsorption was P(S/MAA) > PS or P(S/HEMA), silica > P(MMA/HEMA). Thus, they were also affected by the charged groups and the hydrophilicity of the surfaces. On the other hand, the plateau values of all colloidal particles were more or less symmetrical with a maximum at around the isoelectric point of gamma-globulin at an ionic strength of 0.01. This behavior is attributed to the important role of the lateral interaction between the adsorbed molecules at low ionic strength.
The first lithium manganese oxynitride, Li7.9MnN5 − yOy: preparation and use as electrode material in lithium batteries (2003)

The first lithium manganese oxynitride, Li7.9MnN5 − yOy, was obtained by solid state reaction of binary nitrides and lithium oxide under nitrogen flow. It is an interesting candidate for negative electrode material in lithium ion batteries yielding a reversible capacity of 310 mAh g−1.
Antibacterial Screening of Some Synthesized Palmitoyl Amino Acids and Their Aromatic Analogues (2014)

Journal of Pharmaceutical Research International (ISSN: 2456-9119) is dedicated to publish high quality papers in all areas of pharmaceutical Science including pharmaceutical drugs, community pharmacy, hospital pharmacy, clinical pharmacy, compounding pharmacy, consultant pharmacy, internet pharmacy, veterinary pharmacy, nuclear pharmacy, military pharmacy, pharmacy informatics, pharmaceutics, medicinal chemistry, pharmacognosy, pharmacotherapy, pharmacodynamics, pharmacokinetics, clinical pharmacology, neuropharmacology, psychopharmacology, pharmacogenetics, pharmacogenomics, pharmacoepidemiology, toxicology, theoretical pharmacology, posology, pharmacognosy, behavioral pharmacology, environmental pharmacology, medicine development and safety testing, drug legislation and safety, pharmaceutical microbiology, pharmaceutical molecular biology, pharmaceutical biotechnology. The journal also encourages the submission of useful reports of negative results. This is a quality controlled, OPEN peer reviewed, open access INTERNATIONAL journal.
Efficient Simulation of Arbitrary Multicomponent First-Order Binding Kinetics for Improved Assay Design and Molecular Assembly (2021)

Traditional enzyme-linked immunosorbent assay (ELISA), long the workhorse for specific target protein detection using microplate wells, is nearing its fundamental limit of sensitivity. New opportunities in health care call for <i>in vitro</i> diagnostic tests with ultrahigh sensitivity. Magnetic bead-based sandwich immunoassay formats have been developed that can reach unprecedented sensitivities, orders of magnitude better than are allowed for by the rate constants for a single ligand-receptor interaction. However, these ultrahigh sensitivity assays are vulnerable to a host of confounding factors, including nonspecific binding from background molecules and loss of low-abundance target to tube walls and during wash steps. Moreover, the optimization of workflow is often time-consuming and expensive. In this work, we present a simulation tool that allows users to graphically define arbitrary binding assays, including fully reversible first-order binding kinetics, timed addition of extra components, and timed wash steps. The tool is freely available as a user-friendly webapp. The framework is lightweight and fast, allowing for inexpensive simulation and visualization of arbitrarily complex assay schemes, including but not limited to digital immunoassays, DNA hybridization, and enzyme kinetics, for validation and optimization of assay designs without requiring any programming knowledge from the user. We demonstrate some of these capabilities and provide practical guidance on assay simulation design.