gebhart/patrepeval huggingface dataset:
Linear and nonlinear heart rate variability risk stratification in heart failure patients (2008)

Chronic heart failure (CHF) is a major and growing public health concern (∼23 million people worldwide) with five-year survival rates of 25% in men and 38% in women. Objective of this study was to investigate whether linear and nonlinear heart rate variability (HRV) indices enhance risk prediction in patients with CHF. To discriminate between low risk (stable condition, N=459) and high risk (cardiac death, N=50) CHF patient groups, nonlinear indices from compression entropy (CE), detrended fluctuation analysis (DFA), symbolic dynamics (SD) and standard linear HRV analysis were calculated from 24h Holter ECG recordings. Indices from nonlinear dynamics (CE, DFA, SD: p≪0.001) contribute together with clinical parameters NYHA and LVEF to an enhanced risk stratification in CHF patients.
F0-CONTOURS IN EMOTIONAL SPEECH (1999)

Emotions influence a person’s way of speaking, and it is possible to identify the emotional state of a speaker by merely listening to spoken utterances. The purpose of this study is to distinguish between basic emotions by prosodic features, in particular by characteristics of the fundamental frequency (F 0). In addition to the measurement of global features (e.g. average F 0 or frequency range) a number of more detailed features are examined. These parameters among others are the direction and steepness of F 0 changes on syllable level and the F 0 contour over whole utterances after a stylization procedure. Furthermore, the intrasyllabic F 0 contour without stylization is investigated. The majority of the results can be used to distinguish between the emotions fear, anger, happiness, sadness, boredom, and disgust. 1.
Annealing of Thin-film Cadmium Telluride Photovoltaics Using Holographically Controlled Laser Processing (2016)

CdTe-based thin film solar cells currently represent one of the fastest growing PV technologies, with a superior combination of efficiency, energy payback time and lifecycle environmental impact. However, the current post-deposition annealing treatment is still an energy intensive step of the manufacturing process. A novel method is presented for annealing of CdTe using a high-power diode laser (35 W, 808 nm) for thermal post-processing, combined with holographic optical elements (HOE's) for laser beam heat flow control. The advantage of a laser for annealing lies in its ability to selectively heat only the surface of the CdTe solar cell; improving energy efficiency, process speed and energy resilience. Heat transfer simulations were used to predict the effects of different laser irradiance profiles on the annealing process thermal cycle influence the experimental design and predict optimal laser irradiance profiles. Variations in power and process speed on as-deposited and MgCl2-treated close-space sublimated (CSS) CdTe samples have been performed. The results were characterised using scanning electron microscopy (SEM), transmission electron microscopy (TEM) and X-ray photoelectron spectroscopy (XPS). Optical properties were analysed with a spectrophotometer and ellipsometric spectroscopy (SE). The laser annealing treatment was found to be effective in promoting Chlorine diffusion and improving the optical and morphological properties of CdTe thin film devices.
Bend the Coin Your Way: Ligand Design and Main Group Element Chemistry (2001)

The dibenzo[a,d]cycloheptatrienyl residue is introduced as platform for the high-yield synthesis of new rigid phosphanes (tropp ligand system) and phosphiranes (BABAR-phos); strained three-membered heterocycles. With tropp as ligands, transition metal complexes with unusual low oxidation states at the metal center could be prepared and isolated. Especially mononuclear paramagnetic rhodium(O) and iridium(O) complexes could be studied in detail. The BABAR-phos compounds show very high thermal and chemical stability, i.e. they are remarkably stable against oxygen, sulfur, strong alkylating agents, and aqueous acid and base. Rhodium(l) complexes with BABAR-phos proved to be highly stable active catalyst precursors for hydroborations.
Using Fourier information for the detection of the lumen in endoscope images (2002)

An endoscope is a viewing instrument used for examining the inside surfaces of the human body for the purpose of diagnosis and minor surgical treatment. To date, only highly skilled specialists have been able to perform endoscopic investigations. We are proposing to rectify this situation by using computer vision to provide automatic guidance and advice during colonoscopy. In order to navigate an endoscope automatically through the colon, we need to process colon images to extract information, in particular, the position of the lumen (the point to which the endoscope should be directed) with respect to the centre of the image. To achieve this, we have devised and implemented a new Fourier Domain method. Since real time performance is required, we have devised simplified mathematical equations that effectively reduce a 2D FFT (Fast Fourier Transform) into two 1D FFTs. We found it was necessary to use a tapering window to minimize the edge discontinuity problem that leads to mis-classification. The results that we have obtained demonstrate that the method is highly effective in identifying the lumen position.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Design and long-term operation of high-temperature, bulk-CMOS integrated circuits for instrumentation and control (2013)

Researchers at Case Western Reserve University (CWRU) and BluBerry, LLC have worked to extend the useful operating temperature range of low-cost, bulk CMOS instrumentation and actuation ICs to greater than 200°C. In this manuscript, we review the motivation, challenges, and circuit techniques employed to operate bulk CMOS circuits at extended temperatures. Initial research at CWRU yielded monolithic clock oscillators, instrumentation amplifiers, and sigma-delta analog-to-digital converters capable of stable, high-performance operation beyond 200°C. To demonstrate the industrial potential for this technology, a set of three integrated circuits (ICs) was developed to support distributed engine controls for aerospace applications. The ICs were fabricated in a conventional, 0.5-μm bulk CMOS process and, in combination with a high-temperature microcontroller, include all the circuits required to form a “smart node” capable of providing local, closed-loop control of an aircraft actuator. Operation of the circuits has been demonstrated from -55 to 200°C on representative flight hardware. Long-term testing has shown that the custom ICs can withstand continuous operation at elevated temperatures for more than 4,500 hours with negligible performance shift.
Nucleotide diversity and population differentiation of the Melanocortin 1 Receptor gene, MC1R (2008)

This study further quantifies the degree of population-specific genetic variation and suggests that positive selection may be present in European populations in MC1R.
One Bad Apple Spoils the Bunch: Transaction DoS in MimbleWimble Blockchains (2021)

As adoption of blockchain-based systems grows, more attention is being given to privacy of these systems. Early systems like BitCoin provided few privacy features. As a result, systems with strong privacy guarantees, including Monero, Zcash, and MimbleWimble have been developed. Compared to BitCoin, these cryptocurrencies are much less understood. In this paper, we focus on MimbleWimble, which uses the Dandelion++ protocol for private transaction relay and transaction aggregation to provide transaction content privacy. We find that in combination these two features make MimbleWimble susceptible to a new type of denial-of-service attacks. We design, prototype, and evaluate this attack on the Beam network using a private test network and a network simulator. We find that by controlling only 10% of the network nodes, the adversary can prevent over 45% of all transactions from ending up in the blockchain. We also discuss several potential approaches for mitigating this attack.
Rapid detection of Legionella species in bronchoalveolar lavage fluids with the EnviroAmp Legionella PCR amplification and detection kit (1993)

A molecular assay based on a rapid DNA extraction protocol and the EnviroAmp Legionella Kits was used to detect Legionella species in bronchoalveolar fluid specimens. All Legionella strains isolated from tap water in hospitals could be detected distinctly. Both sensitivity and specificity were tested. In a prospective study, bronchoalveolar lavage fluids obtained from patients with atypical pneumonia were investigated. Three positive samples were detected with the molecular techniques and were subsequently confirmed by culture. Application of the system described may lead to safe and early diagnosis of Legionnaires' disease in patients with atypical pneumonia.
Efficient Photoswitching of the Nonlinear Optical Properties of Dipolar Photochromic Zinc(II) Complexes (2007)

Flipping the switch: A new type of bipyridine-based ligand functionalized by phenyl- and dimethylaminophenyldithienylethene groups allows the preparation of photochromic dipolar zinc(II) complexes. For the first time, efficient on/off photoswitching of the NLO response of metallochromophores is observed. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2008/z704138_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Detection and characterization of novel bioactive peptides using Electrical Impedance Spectroscopy (2015)

status: Published
Lake‐specific variation in growth, migration timing and survival of juvenile sockeye salmon Oncorhynchus nerka: separating environmental from genetic influences (2010)

Time series on juvenile life-history traits obtained from sockeye salmon Oncorhynchus nerka were analysed to assess lake-specific environmental influences on juvenile migration timing, size and survival of fish from a common gene pool. Every year for the past two decades, O. nerka have been spawned at a hatchery facility, and the progeny released into two lakes that differ in average summer temperatures, limnological attributes and growth opportunities. Juveniles reared in the warmer, more productive Crosswind Lake were larger and heavier as smolts compared to those from the cooler, less productive Summit Lake and had higher in-lake and subsequent marine survival. Crosswind Lake smolts migrated from the lake to sea slightly earlier in the season but the migration timing distributions overlapped considerably across years. Fry stocking density had a negative effect on smolt length for both lakes, and a negative effect on in-lake survival in Summit Lake. Taken together, the results revealed a strong effect of lake-rearing environment on the expression of life-history variation in O. nerka. The stocking of these lakes each year with juveniles from a single mixed-source population provided a large-scale reverse common-garden experiment, where the same gene pool was exposed to different environments, rather than the different gene pools in the same environment approach typical of evolutionary ecology studies. Other researchers are encouraged to seek and exploit similar serendipitous situations, which might allow environmental and genetic influences on ecologically important traits to be distinguished in natural or semi-natural settings.
A Beast in the Field: The Google Maps Mashup as GIS/2 (2006)

Over the last decade or more, geographic information systems (GIS) have proved themselves nimble and potent tools in myriad academic, civic, and political disciplines. A body of scholarship followed GIS on its rise to wider acceptance and adoption, however, that questioned its nature and the way its power was wielded. This scholarship ultimately produced various models for “GIS/2,” an amalgam of GIS's power and the grassroots democratic activity that might have been fostered by it but largely was not. This article revisits going models of GIS/2 and finds them to be so much vapourware compared to recent developments in online geospatial applications. The article argues that for all of the well-intentioned effort put into GIS/2 theory, the most progressive real-world candidate for GIS/2 has been produced only recently, by another rare combination indeed: two Austin, Texas, 20-somethings and the online search monolith Google. The Google Maps mashup, a very twenty-first-century beast born of code from disparate Web applications, exhibits great potential to be a real live GIS/2. Moreover, there is one mashup in particular that, while perhaps not quite mature enough to realistically match 15 years of GIS/2 scholarship, is still possibly the finest working example yet of the ideas and concepts posited therein.
Retinoid X receptor-COUP-TF interactions modulate retinoic acid signaling. (1992)

We have recently described the properties of direct repeats (DRs) of the half-site AGGTCA as hormone response elements (HREs). According to our results, spacing the half sites by 3, 4, or 5 nucleotides determines specificity of response for vitamin D3, thyroid hormone, and retinoic acid receptors, respectively. This so-called 3-4-5 rule led to the prediction that remaining spacing options of 0, 1, and 2 might serve as targets for other nuclear receptors. A concurrent prediction is that receptors recognizing common sites might display more complex or combinatorial interactions. In exploring these predictions, we discovered that both the retinoid X receptor (RXR) and COUP-TF bind preferentially to a DR-1 motif. In vivo, RXR and COUP-TF display antagonistic action such that RXR-mediated activation is fully repressed by COUP-TF. In vitro studies reveal that COUP-TF and RXR form heterodimers on DR-1. Thus, these results support a general proposal in which the half-site spacing preferences may be used as a means to decipher potentially complex and interactive regulatory circuits.
Approaches to the rationalization of surgical instrument trays: scoping review and research agenda (2021)

To the best of our knowledge, ours is the first study that reviews and systematizes the existing literature on the subject of STR. Our study closes with the proposition of future research directions, which are presented as nine research questions associated with the four generic steps proposed in the STR roadmap.
Inequality-constrained 3D Morphable Face Model Fitting (2022)

&lt;p&gt;A new 3D morphable model (fitting) framework, based on inequality-constrained optimization and gradient correlation. An optimization-based method that does not require any training, and works robustly. Moreover, the method is capable of simultaneously fitting a 3DMM to multiple frames of a person. Finally, camera matrix can be injected.&lt;/p&gt;
Reagents for Organic Synthesis: Use of Organostannyl Oxides as Catalytic Neutral Agents in the Preparation of Nitriles from Primary Amides under Microwave Irradiation (1999)

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTReagents for Organic Synthesis: Use of Organostannyl Oxides as Catalytic Neutral Agents in the Preparation of Nitriles from Primary Amides under Microwave Irradiation†D. Subhas Bose and B. JayalakshmiView Author Information Organic Chemistry Division III, Indian Institute of Chemical Technology, Hyderabad 500 007, India Cite this: J. Org. Chem. 1999, 64, 5, 1713–1714Publication Date (Web):February 10, 1999Publication History Received9 September 1998Published online10 February 1999Published inissue 1 March 1999https://pubs.acs.org/doi/10.1021/jo981839ohttps://doi.org/10.1021/jo981839obrief-reportACS PublicationsCopyright © 1999 American Chemical SocietyRequest reuse permissionsArticle Views1104Altmetric-Citations54LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Amides,Electromagnetic radiation,Nitrogen compounds,Oxides,Reagents Get e-Alerts
Regulation of interleukin 2 production, interleukin 2 mRNA expression and intracellular glutathione levels in ex vivo derived T lymphocytes by lactate (1991)

The concentration of L-lactate in the blood plasma of higher vertebrates is about 1 mM but can be as high as 30 mM under certain physiological and pathological conditions or in the vicinity of glycolytically active cells including macrophages. Here we report that high but physiologically relevant concentrations of lactate increase the expression of interleukin 2 (IL 2)-specific mRNA and the production of IL 2 activity in cultures of mitogenically stimulated T cells. Lactate supports IL 2 production most effectively if added 0-8 h after T cell stimulation and only in cultures of CD4+ but not of CD8+ T cells. In contrast to the DNA synthesis activity in these cell cultures, IL 2 production is not augmented but rather inhibited by exogenous glutathione (GSH). Lactate causes a reduction of intracellular GSH levels, and lactate-containing cultures require accordingly higher extracellular cysteine concentrations than control cultures to achieve similar intracellular GSH levels. In view of the strong variations of extracellular lactate concentrations in vivo, our experiments suggest that lactate may be part of a previously unknown mechanism by which the metabolic microenvironment modulates gene expression in T cells.
Solving 94-Bit Ecdlp With 70 Computers In Parallel (2015)

Elliptic curve discrete logarithm problem(ECDLP) is one of problems on which the security of pairing-based cryptography is based. This paper considers Pollard's rho method to evaluate the security of ECDLP on Barreto-Naehrig(BN) curve that is an efficient pairing-friendly curve. Some techniques are proposed to make the rho method efficient. Especially, the group structure on BN curve, distinguished point method, and Montgomery trick are well-known techniques. This paper applies these techniques and shows its optimization. According to the experimental results for which a large-scale parallel system with MySQL is applied, 94-bit ECDLP was solved about 28 hours by parallelizing 71 computers.
[Research on bending strength and fracture toughness of alumina-glass composite]. (1998)

To develop a new ceramic material that can be machined and infiltrated with glass, a porous alumina blank sintered at 1350 degrees C was made of high purity, super fine alpha-alumina and then infiltrated with glass in this study. The density, bending strength and fracture toughness of the partially sintered alumina and alumina-glass composite were determined. The results indicated that the porous alumina density was 2.12 g/cm3, the three point bending strength 102 MPa, the fracture toughness 1.61 MPam1/2; that the alumina-glass composite density was 3.85 g/cm3, the three point bending strength 385 MPa, and the fracture toughness 4.05 MPam1/2. By SEM and EDXA analysis, lanthanum boroslicate glass was completely infiltrated into the 3 mm thick porous alumina blank for 6 h at 1150 degrees C. These suggest that the new developed alumina blank is suited for clinical use.
Solvothermal synthesis of hierarchical flower-like β-NiS with excellent electrochemical performance for supercapacitors (2013)

A hierarchical flower-like β-NiS architecture has been successfully synthesized via a solvothermal method with diethanolamine as the coordination agent and solvent. When evaluated as an electrode material for supercapacitors, impressive electrochemical performances are achieved, with high specific discharge capacitances of 857.76 F g−1 at 2 A g−1 and 512.96 F g−1 at 5 A g−1.
A la búsqueda de las cuidades intermedias. Algunos elementos de reflexión (2015)

International audience
Laboratory simulated hydrothermal alteration of sedimentary organic matter from Guaymas Basin, Gulf of California (1993)

High temperature alteration of sedimentary organic matter associated with marine hydrothermal systems involves complex physical and chemical processes that are not easily measured in most natural systems. Many of these processes can be evaluated indirectly by examining the geochemistry of the hydrothermal system in the laboratory. In this investigation, an experimental organic geochemical approach to studying pyrolysis of sedimentary organic matter is applied to the hydrothermal system in the Guaymas Basin, Gulf of California. A general survey of hydrothermal oils and extractable organic matter (bitumen) in hydrothermally altered sediments identified several homologous series of alkanones associated with a high temperature hydrothermal origin. The alkanones range in carbon number from C11 to C30 with no carbon number preference. Alkan-2-ones are in highest concentrations, with lower amounts of 3-, 4-, 5- (and higher) homologs. The alkanones appear to be pyrolysis products synthesized under extreme hydrothermal conditions. Hydrous pyrolysis and confinement pyrolysis experiments were performed to simulate thermally enhanced diagenetic and catagenetic changes in the immature sedimentary organic matter. The extent of alteration was measured by monitoring the n-alkanes, acyclic isoprenoids, steroid and triterpenoid biomarkers, polycyclic aromatic hydrocarbons and alkanones. The results were compared to bitumen extracts from sediments which have been naturally altered by a sill intrusion and accompanied hydrothermal fluid flow. These pyrolysis experiments duplicated many of the organic matter transformations observed in the natural system. Full hopane and sterane maturation occurred after 48 hr in experiments at 330 deg C with low water/rock mass ratios (0.29). A variety of radical and ionic reactions are responsible for the organic compound conversions which occur under extreme hydrothermal conditions. Short duration pyrolysis experiments revealed that a portion of the hydrocarbons generated from kerogen was observed to go through alkene intermediates, and the rate of alkene isomerization was influenced by the ionic strength and catalytic mineral phases. Confinement of the organic pyrolysate to the bulk sediment accelerated the rates of the biomarker epimerization reactions, suggesting that these reactions are influenced strongly by the association of the inorganic matrix, and that the relative rates of some ionic and radical reactions can be influenced by the water/rock ratio during the pyrolysis experiments.