gebhart/patrepeval huggingface dataset:
Design and synthesis of a squaraine dye for long wavelength fluorescence-based biosensors (2005)

The design and synthesis of an environmentally sensitive long wavelength fluorescing squaraine dye for conjugation to proteins is dsecribed. Environmentally sensitive dyes are valuable for probing environmental changes that occur when labeled proteins bind their corresponding ligands and can be used to construct flyorescent sensors. Long wavelength (&gt;650 nm) dyes would enable through-skin wireless sensing with minimum interference from the background. While several environmentally sensitive dyes are known in the visible spectrum, only a few are available in the long wavelength region, and none of them are available with reactive groups suitable for protein conjugation. Several derivatives of squarain dyes are known to be environmentally sensitive and fluorescent in the long wavelength region, but none of them are available with linkers for protein conjugation. In order to achieve this goal, we developed a synthetic scheme to introduce a reactive linker onto an anilinic squaraine that is highly sensitive to its environment. The synthesis involves the preparation of the dye with an iodoacetyl ester linker that readily reacts with a thiol on a cysteine residue of the binding protein. The squaraine dye was conjugated to known binding proteins that were evaluated as optical sensors. Ultimately, we expect these systems to measure analytes in the body and transmit information through the skin to an external monitor.
Synthesis of a Family of {[(VSe2)n] 1.06(TaSe2)m}z Compounds. (2007)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Description and Validation of a Test System to Investigate the Evaporation of Spray Droplets (1995)

This paper describes a laboratory test system in which droplet evaporation data are generated from experiments conducted entirely within a controlled environment chamber. Validation of the test system using deionized water is described. Observed results of evaporation as a function of time are compared to the theoretical predictions of the Goering model for a range of temperature, relative humidity and wind speed conditions.
Visual-hull reconstruction from uncalibrated and unsynchronized video streams (2004)

We present an approach for automatic reconstruction of a dynamic event using multiple video cameras recording from different viewpoints. Those cameras do not need to be calibrated or even synchronized. Our approach recovers all the necessary information by analyzing the motion of the silhouettes in the multiple video streams. The first step consists of computing the calibration and synchronization for pairs of cameras. We compute the temporal offset and epipolar geometry using an efficient RANSAC-based algorithm to search for the epipoles as well as for robustness. In the next stage the calibration and synchronization for the complete camera network is recovered and then refined through maximum likelihood estimation. Finally, a visual-hull algorithm is used to the recover the dynamic shape of the observed object. For unsynchronized video streams silhouettes are interpolated to deal with subframe temporal offsets. We demonstrate the validity of our approach by obtaining the calibration, synchronization and 3D reconstruction of a moving person from a set of 4 minute videos recorded from 4 widely separated video cameras.
Performance Enhancement of Cyclostationarity Detector by Utilizing Multiple Cyclic Frequencies of OFDM Signals (2010)

Spectrum sensing is a key technical challenge for the cognitive radio (CR) technology which allows it to access the spectrum of the licensed systems without causing interference to them. It is well known that cyclostationarity detectors have a great advantage of the robustness of noise uncertainty which significantly degrades the performance and makes its implementation difficult in energy detectors. This paper pays attention to the fact that cyclostationarity detector can acheive diversity gain by manipulating multiple cyclic autocorrelation functions (CAFs). While most of combining schemes in cooperative sensing with multiple detectors require the signal to noise power ratio estimation which is impractical in low SNR regime, combining with multiple CAFs in single detector based on transmit signal characteristic can be used. In this paper, three detector schemes of selection combining (SC), equal gain combining (EGC) and maximum ratio combining (MRC) with multiple CAFs are evaluated in additive white Gaussian noise (AWGN) channel considering the OFDM signal of Japanese digital television broadcasting (ISDB-T) as a primary system. The numerical results will show that the cyclic detector based on MRC using several cyclic frequencies has the best detection performances even though EGC shows slightly worse performance in assumed condition.
Bis(N,N-dimethylthiocarbamoylthio)acetic acid (2000)

Bis(N,N-dimethylthiocarbamoylthio)acetic acid, [(CH(3))(2)NC(=S)S](2)CHC(=O)OH or C(8)H(14)N(2)O(2)S(4), exists as a centrosymmetric hydrogen-bonded dimer [O.O 2.661 (3) A].
Seismic interferometry with a TBM source of transmitted and reflected waves (2006)

Abstract We discuss the use of autocorrelogram interferometry by using noise from the tunnel-boring machine (TBM). The TBM provides seismic signals/waves while drilling in a tunnel (TSWD). The tunnel geometry, unlike a reverse vertical seismic profile (RVSP) using a drill bit, makes it possible to record the waves reflected from the region between the tunnel face and the projected tunnel exit and those transmitted ahead of the tunnel face. We processed the waves recorded at back positions with respect to the TBM in a manner similar to a RVSP data set obtained by conventional reference-correlation techniques. We processed the waves transmitted ahead of the TBM using autocorrelogram interferometry techniques. Using these wavefields offers advantages over conventional borehole drill-bit vertical seismic profiles (VSPs). The most important advantage is getting reflections from the transmitted (front) wavefield by utilizing Kunetz's equation and reversed-time traces. The approach also improves the analysis of the transmitted amplitudes. Finally, we improved the deconvolution of the reflected (back) waves by using the transmitted wavefields measured for interferometry purposes. In particular, by using both front (transmitted) and back (reflected) waves, it is possible to deconvolve the signature of the source extended spatially along the tunnel axis. We use a 1D model in which the interfaces are assumed subvertical. We present a case history in which TSWD data were acquired in a tunnel measuring 950 m long. We compare results from the transmitted reversed-time and back-reflected waves (S-waves) with those obtained by amplitude analysis and estimation of reflection coefficients. Each approach matches the interpretation of the fractures encountered in the tunnel.
—The Plant (US) (2003)

The Plant Recording Studios in Sausalito, California opened their doors in 1972. Located just north of San Francisco, the studios were built by Chris Stone and Gary Kellgren, founders of the Los Angeles/Hollywood counterpart, the Record Plant. Stone and Kellgren wanted studios that would serve as a
Designing Film-Cooled Turbine Disks (1988)

Technique optimizes weight and speeds of disks in film-cooled turbines. Proposed iterative approach to design enables shaping of turbine disks partly according to temperature profiles. Suitable for design of advanced stationary, aircraft, and rocket turbines.
Spacer Fabrics – A Potential Tool in the Prevention of Chronic Wounds (2002)

Spacer fabrics are special textiles that offer designed qualities for pressure relief as well as regulation of heat and moisture. Investigations of the physical properties of these textiles demonstrate favourable qualities for their potential use in the medical field. The application of spacer fabrics for the prevention of chronic wounds is just beginning. However, typical fields of application are primary prevention of pressure sores in the operation room, secondary prevention of pressure sores for wheelchair drivers and the prevention of plantar ulcers in patients with the diabetic foot syndrome. Spacer-fabric-based bandages seem to be useful in oedema treatment in cases of chronic venous insufficiency and chronic lymphatic insufficiency.
Discernment of chemical shift in MRMI system simulation (2005)

Abstract:- This paper describes an industrial magnetic resonance multiple imaging (MRMI) system that measures nuclear magnetic resonance of several kinds of nuclei and functional group simultaneously. We use a new reconstruction principle of CT. Then we reconstruct distribution images of nuclear magnetic resonance (NMR) without using usual gradient coils. We propose an image reconstruction method of a new industrial MRMI for non-destructive test. Finally, we show simulation results for it.
Autophagy linked FYVE (Alfy/WDFY3) is required for establishing neuronal connectivity in the mammalian brain (2016)

The regulation of protein degradation is essential for maintaining the appropriate environment to coordinate complex cell signaling events and to promote cellular remodeling. The Autophagy linked FYVE protein (Alfy), previously identified as a molecular scaffold between the ubiquitinated cargo and the autophagic machinery, is highly expressed in the developing central nervous system, indicating that this pathway may have yet unexplored roles in neurodevelopment. To examine this possibility, we used mouse genetics to eliminate Alfy expression. We report that this evolutionarily conserved protein is required for the formation of axonal tracts throughout the brain and spinal cord, including the formation of the major forebrain commissures. Consistent with a phenotype reflecting a failure in axon guidance, the loss of Alfy in mice disrupts localization of glial guidepost cells, and attenuates axon outgrowth in response to Netrin-1. These findings further support the growing indication that macroautophagy plays a key role in the developing CNS.
Aviation Cybersecutiry: Cyberattacks Are a Threat For Everyone (2017)

A discussion of protection of aviation systems from cyber threats.
Incidence and prognostic significance of extramural venous invasion in T3-4 esophageal cancer. (2017)

44 Background: Extra mural venous invasion (EMVI) is known as an adverse prognostic indicator of survival and an important predictor of systemic recurrences in colorectal carcinoma. However, the incidence and significance of EMVI in esophageal cancer (EC) have not been studied well. Aim: To estimate the incidence and the prognostic significance of EMVI in pathological stage T3-4 EC resection specimens without neoadjuvant chemoradiotherapy (nCRT) Methods: From a prospective maintained database we retrospectively review the resected specimens of patients with an EC. For adequate EMVI assessment we only included patients without nCRT and excluded patients without previous malignancies and patients with cardia/gastroesophageal junction tumors. A total of 76 patients were included between 2000 and 2012. EMVI was assessed on haematoxylin and eosin slides and for confirmation additional Elastica van Gieson staining was performed. Disease free survival was analyzed using a multivariable logistic regression and Kaplan-Meier method. Results: Evidence of EMVI was found in 18 patients (23.7%). The incidence of EMVI was significantly higher in squamous cell carcinomas (p &lt; 0.05) and among tumors located in the mid-esophagus (p &lt; 0.05). In the univariate analysis, pathological N- stage (HR 3.6 95%Cl: 1.5-8.5; p = 0.004) and positive circumferential resection margin (CRM) (HR 2.3 95% Cl: 1.2-4.5 p = 0.015) were independent prognostic factors. By stepwise multivariate Cox regression analysis, pathological tumor length (HR 2.5 95%Cl: 1.0-6.5 p = 0.05), pathological N- stage (HR 2.7 95%Cl: 1.3-6.2 p = 0.008), positive CRM (HR 2.3 95% Cl: 1.2-4.5 p = 0.009) and EMVI (HR 2.2 95% Cl: 1.0-4.5 p = 0.04) were shown to be independent prognostic factors for disease free survival. Conclusions: A search for EMVI may provide additional prognostic information in esophageal cancer, especially in squamous cell carcinoma.
ChemInform Abstract: QUANTITATIVE ROSTANALYSE DURCH MOESSBAUER‐SPEKTROMETRIE (1972)

Abstract Durch Auswertung der Teilintensitäten der Komponenten im Mössbauer‐Spektrum von Rostproben kann deren Zusammensetzung quantitativ bestimmt werden.
Description of polarisation dependence of two-photon absorption in silicon avalanche photodiodes (2010)

A simple formula is obtained that very accurately describes the level of two-photon absorption (TPA) generated by elliptically polarised light in silicon avalanche photodiodes (Si-APDs). The dichroism parameter necessary to describe the polarisation dependence of TPA in Si-APDs at room temperature is determined to be +0.372 in the region of 1550 nm.
ESR study of the electronic structures of metallofullerenes: a comparison between lanthanum fullerene (La@C82) and scandium fullerene (Sc@C82) (1993)

ADVERTISEMENT RETURN TO ISSUEArticleNEXTESR study of the electronic structures of metallofullerenes: a comparison between lanthanum fullerene (La@C82) and scandium fullerene (Sc@C82)Tatsuhisa Kato, Shinzo Suzuki, Koichi Kikuchi, and Yohji AchibaCite this: J. Phys. Chem. 1993, 97, 51, 13425–13428Publication Date (Print):December 1, 1993Publication History Published online1 May 2002Published inissue 1 December 1993https://pubs.acs.org/doi/10.1021/j100153a001https://doi.org/10.1021/j100153a001research-articleACS PublicationsRequest reuse permissionsArticle Views319Altmetric-Citations68LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Curve Alignment for Well-to-Well Log Correlation (2004)

Abstract This paper presents a novel curve alignment program based on dynamic programming applied to well-to-well log correlation. The dynamic time warping (DTW) algorithm for data mining and signal processing is adapted to work on depth sampled well log data. Analytical tools to assist evaluation of curve alignment are provided. Our implementation can be described as automated, interactive, and constrained. Mathematical optimization - dynamic programming - provides the algorithmic, "automated" part of our solution to the well log correlation problem. "Interactive" means that the process is fast enough to be used interactively, and that it should be used iteratively, supplying visual and quantitative feedback to user identification of markers common to both wells. "Constrained" means that decisions by an educated user such as a geologist or a geophysicist, about depth ranges to which the algorithmic is applied is important, as are decisions about acceptance or rejection of particular results. The key to success has been display of pick selection mapped from posted depths in a "reference well" at depths on the "target" well, and the provision of interactive features so that the program be guided in the search for good problem solutions.
Towards 2+1 photon tomography: Energy-based selection of two 511 keV photons and a prompt photon with the J-PET scanner (2018)

The possibility to separate signals caused by 511 keV photons created in annihilation of electron-positron pairs and the so-called prompt photons from nuclei de- excitation is investigated. It could potentially be used to improve the quality of reconstructed images in the J-PET scanner in 2+1 photon tomography. Firstly, a research is conducted for several radioisotopes that decay via \b{eta}+ decay followed by de-excitation of an excited nucleus. Efficiency, purity and false positive rate are calculated for each isotope as a function of energy deposited threshold, with a hypothesis that signals caused by 511 keV photons deposit smaller values of energy than 1 z 13the selected threshold, while prompt photons deposit larger energy than the threshold. Analysis of the results accompanied with physical properties of radioisotopes suggests using 44 Sc, which is the most promising candidate for medical applications. With the use of GATE and J-POS simulation software, in-phantom scattering was introduced and the best energy deposited threshold value was estimated to be approximately 375 keV. It corresponds to almost 100% efficiency for 511 keV signals, 75% purity for 511 keV photons, and approximately 70% efficiency and purity for prompt photons.
A Practical Asymmetric Synthesis of the Antiviral Agent Lobucavir, BMS-180194 (1998)

A practical synthesis of the antiviral agent lobucavir, [1R-(1α,2β,3α)]-2-amino-9-[2,3-bis(hydroxymethyl)cyclobutyl]-6H-purin-6-one (BMS-180194), is described. The key chiral intermediate, [1S-(1α,2β,3α)]-3-hydroxy-1,2-cyclobutanedimethanol, dibenzoate ester, was made by an asymmetric [2 + 2] cycloaddition of dimenthyl fumarate with ketene dimethyl acetal followed by sequential diester reduction, benzoylation, deketalization, and stereoselective ketone reduction. Regioselective N9-alkylation of the tetra-n-butylammonium salt of 2-amino-6-iodopurine with the derived cyclobutyltriflate furnished the purinecyclobutyl dibenzoate. Methanolysis followed by acid hydrolysis produced lobucavir in a 35% overall yield with an ee > 99%.
Inhibition of Polyamine Uptake Potentiates the Anti‐Proliferative Effect of Polyamine Synthesis Inhibition and Preserves the Contractile Phenotype of Vascular Smooth Muscle Cells (2015)

Increased vascular smooth muscle cell (VSMC) proliferation is a factor in atherosclerosis and injury-induced arterial (re) stenosis. Inhibition of polyamine synthesis by α-difluoro-methylornithine (DFMO), an irreversible inhibitor of ornithine decarboxylase, attenuates VSMC proliferation with high sensitivity and specificity. However, cells can escape polyamine synthesis blockade by importing polyamines from the environment. To address this issue, polyamine transport inhibitors (PTIs) have been developed. We investigated the effects of the novel trimer44NMe (PTI-1) alone and in combination with DFMO on VSMC polyamine uptake, proliferation and phenotype regulation. PTI-1 efficiently inhibited polyamine uptake in primary mouse aortic and human coronary VSMCs in the absence as well as in the presence of DFMO. Interestingly, culture with DFMO for 2 days substantially (>95%) reduced putrescine (Put) and spermidine (Spd) contents without any effect on proliferation. Culture with PTI-1 alone had no effect on either polyamine levels or proliferation rate, but the combination of both treatments reduced Put and Spd levels below the detection limit and inhibited proliferation. Treatment with DFMO for a longer time period (4 days) reduced Put and Spd below their detection limits and reduced proliferation, showing that only a small pool of polyamines is needed to sustain VSMC proliferation. Inhibited proliferation by polyamine depletion was associated with maintained expression of contractile smooth marker genes. In cultured intact mouse aorta, PTI-1 potentiated the DFMO-induced inhibition of cell proliferation. The combination of endogenous polyamine synthesis inhibition with uptake blockade is thus a viable approach for targeting unwanted vascular cell proliferation in vivo, including vascular restenosis.
Chimie Douce Synthesis of a Layered Ammonium Zinc Molybdate (1996)

A layered ammonium zinc molybdate material was derived by a novel room-temperature chimie douce synthesis technique from a metastable mixed oxide prepared by calcination of a layered double hydroxide (LDH). The compound obtained, (NH4)HZn2(OH)2(MoO4)2, is highly crystalline and retains the rhombohedral symmetry of the LDH precursor. The crystal structure of this material was determined by Rietveld refinement of an isostructural ammonium nickel molybdate. The structure is trigonal, with hexagonal unit-cell parameters of a = 6.10767(15) Å and c = 21.6409(6) Å. The host structure consists of divalent cation octahedra which share edges to form layers perpendicular to the c axis, analogous to the LDH precursor. The tetrahedral molybdate species, however, are not merely intercalated within the interlayer domain but are bonded to the layers themselves through shared Mo−O−Zn bonds. This arrangement results in the formation of a net negative charge on the host structure, leading to incorporation of ammonium ions between the layers for charge balancing. The applicability of this novel synthesis route is dependent on the composition of the original LDH, and it appears that metastability in the calcined LDH favors conversion to this phase.
Discrete allyl complexes of group 3 metals and lanthanides (2010)

Allyl complexes based on group IIIb metals (Sc, Y, La) and lanthanides are reviewed. The diversity, synthesis, and main structural and reactivity features of discrete, well-defined homoleptic and pseudo-homoleptic neutral, anionic and cationic bis-, tris- and tetra(allyl)-lanthanide complexes, as well as heteroleptic allyl-lanthanidocenes and allyl-lanthanide complexes supported by non-Cp ligands are covered. Brief comments on the catalytic performances of some key compounds in polymerization processes are also provided.
A Timeout Threshold Estimation Algorithm Based on Equivalent Proportional Execution Time (2018)

A timeout threshold estimation algorithm is proposed which apply in mimic defense systems to reduce the waiting time when timeout is happened. It is inspired by the fact that there is a linear relationship in task execution time of a set of heterogeneous executors in mimic defense systems. Experiment results show that our algorithm can generate a specific timeout threshold for each task with high computational efficiency and is particularly suitable for the scene in which the number of arriving tasks changes drastically.
Using XML as a flexible, portable test script language (2004)

This paper describes the objectives, rationale, implementation and benefits of using Extensible Markup Language (XML) as a test script language in support of a variety of US Army weapon systems. XML provides the ability to implement a simple, flexible, controllable and portable test script language. The use of third party XML parsing and development tools results in decreased test script development times, increased productivity and increased potential for test script reusability and portability.