gebhart/patrepeval huggingface dataset:
Time-resolved spectroscopic study of resonant energy transfer between lead-sulphide quantum dots and bulk silicon (2015)

The brightness, large absorption cross-section and flexibility of colloidal nanocrystal quantum-dots (QDs) make these materials promising candidates for light harvesting applications. The difficulty of efficiently extracting photogenerated carriers from the QDs however drastically limits the power conversion efficiency of NQD solar cells. A possible way to circumvent these issues is to engineer hybrid devices that utilize alternative energy transfer schemes to effectively separate light harvesting and charge extraction in different materials. In this context, hybrid bulk semiconductor/QDs devices coupled through near-field resonant energy transfer offer a promising route towards low cost ultra-thin photovoltaics. In this work, we demonstrate non-radiative resonance energy transfer between lead sulphide (PbS) QDs and bulk silicon using time-resolved spectroscopy.
Cholesterol and Alzheimer's disease: A still poorly understood correlation (2012)

A large amount of evidence suggests a pathogenic link between cholesterol homeostasis dysregulation and Alzheimer's disease (AD). In cell culture systems, the production of amyloid-β (Aβ) is modulated by cholesterol, and studies on animal models have consistently demonstrated that hypercholesterolemia is associated with an increased deposition of cerebral Aβ peptides. Consequently, a number of epidemiological studies have examined the effects of cholesterol-lowering drugs (i.e., statins) in the prevention and the treatment of AD. However, while retrospective studies suggested a potential benefit of statin therapy, clinical trials produced inconsistent results. Here, we summarize the main findings from in vitro and in vivo research where the correlation between cholesterol and the neurodegenerative disorder was investigated. Recognition of this correlation could be an important step forward for our understanding of AD pathogenesis and, possibly, for the development of new therapeutic strategies.
One-dimensional S/sub N/ calculations to evaluate the shielding for an alpha-particle charge exchange neutral analyzer (1988)

One-dimensional discrete ordinates calculations have been carried out to estimate the effectiveness of both concrete and stainless-steel plus borated water shadow shields in reducing the neutron and gamma-ray background levels at an alpha-particle charge exchange neutral analyzer. The system is proposed for studying the alpha particle and plasma characteristics of fusion machines with ignited plasmas such as the CIT. A stainless-steel-borated water shield was determined to be effective in reducing background counting rates. 10 refs., 4 figs., 1 tab.
Systematic control of a class of nonlinear systems with application to electrohydraulic cylinder pressure control (2000)

Develops a systematic methodology for the control of a class of nonlinear systems and applies it to an electrohydraulic system. The class of systems to be dealt with are those that are single input and can be put in strict feedback form. The approach is conceptually similar to previously developed integrator backstepping methodologies. However, unlike some previous investigations which have relied exclusively on a Lyapunov analysis, this work presents a stability analysis using a passivity formulation. There are two main advantages of the proposed approach which become significant during implementation. One practical advantage is that the resulting controller leads to synthetic inputs that are decoupled in a certain sense. This leads to a compartmentalization of modeling error effects associated with the controller. A second advantage of this method is that the system model need not be differentiated in the control formulation. A class of modeling error is introduced and compensated for with the resulting control able to guarantee specified boundary layer tracking. A nonlinear model is developed and verified for an electrohydraulic testbed consisting of a cylinder governed by an electronically controlled servovalve. Finally, the control algorithm is implemented on the testbed and a comparison is made with existing integrator backstepping algorithms. The comparisons demonstrate the benefits of the presented approach.
Synthesis, Molecular Structure and Spectroscopic Investigations of Bis(Halophenylstannyl)‐Methane and Propane Complexes with Hexamethylphosphoric Triamide (1984)

Abstract The reaction of bis(halodiphenylstannyl)methanes with HMPA leads to the formation of the one‐to‐one complexes (Ph 2 XSn) 2 CH 2 . HMPA (X‐Cl,Br,I). The reaction of bis‐1,3(chlorodiphenylstannyl)propane with HMPA yields the one‐to‐two complex (Ph 2 ClSnCH 2 ) 2 CH 2 . 2 HMPA, whereas from bis(dibromophenylstannyl)methanes both the one‐to‐one and the one‐to‐two complexes (PhBr 2 Sn) 2 CH 2 ‐n HMPA (n=1,2) have been isolated. The solid structure of (Ph 2 XSn) 2 CH 2 . HMPA (C=Cl,Br), determined by X‐ray diffraction, shows for both tin atoms a distorted trigonal bipyramidal structure, one by complexation of the HMPA, the other one by intramolecular coordination of a halogen atom. Temperature dependent 1 H, 13 C, 31 P and 119 Sn NMR and IR measurements prove the intramolecular mobility of these compounds.
Synthesis, characterization of bridged bis(amidinate) lanthanide amides and their application as catalysts for addition of amines to nitriles for monosubstituted N-arylamidines (2012)

A series of lanthanide amide complexes supported by bridged bis(amidinate) ligand L, LLnNHAr(1)(DME) (L = [Me(3)SiNC(Ph)N(CH(2))(3)NC(Ph)NSiMe(3)], Ar(1) = 2,6-(i)Pr(2)C(6)H(3), DME = dimethoxyethane, Ln = Y (1), Pr (2), Nd (3), Gd (4), Yb (5)), [Yb(μ(2)-NHPh)](2)(μ(2)-L)(2) (6) and [LYb](2)(μ(2)-NHAr(2))(2) (7) (Ar(2) = (o-OMe)C(6)H(4)), were synthesized by reaction of LLnCl(THF)(2) with the corresponding lithium amide in good yields and structurally characterized by X-ray crystal structure analyses. All complexes were found to be precatalysts for the catalytic addition of aromatic amines to aromatic nitriles to give monosubstituted N-arylamidines. The catalytic activity was influenced by lanthanide metals and the amido groups with the active sequence of Y (1) < Gd (4) < Nd (3) < Pr (2) ∼ Yb (5) for the lanthanide metals and -NHAr(2) < -NHPh < -NHAr(1) for the amido groups. The catalytic addition reaction with complex 5 showed a good scope of aromatic amines. Some key reaction intermediates were isolated and structurally characterized, including the amidinate complexes LLn[NPhCNAr(1)](PhCN) (Ln = Y (8), Ln = Yb (9)), LYb[NAr(2)CNAr(1)](Ar(2)CN) (10), and amide complex 5 prepared by protonation of 9 by Ar(1)NH(2). Reactivity studies of these complexes suggest that the present catalytic formation of monosubstituted N-arylamidines proceeds through nucleophilic addition of an amido species to a nitrile, followed by amine protonolysis of the resultant amidinate species.
Mode-matching in vibrating microgyros using extremum seeking control (2007)

For MEMS vibrating gyroscopes that operate with an open loop sensing interface, the mode-matching condition is essential in order to achieve enhanced sensitivity and uniform performance on the whole sensor bandwidth. Matching the vibrating modes of the sensor during fabrication is rather unfeasible, because the fabrication process tolerances and defects detrimentally affect the manufacturing precision. Moreover, system parameter changes induced by the influence of the external environment can disrupt an initial trimming operated on the device in order to establish mode-matching. So, the only effective way to achieve mode-matching consists of exploiting feedback control. In this paper, we propose an adaptive add-on controller capable of achieving the mode-matching condition in vibratory microgyros operating with an open loop sensing interface. After recasting the mode-matching condition as a maximization problem, we use an extremum seeking control to perform the task of tuning the resonant frequencies of the sensor vibrating modes. The effectiveness of the proposed control scheme is shown by several numerical simulations.
A New Titanium Tetrachloride Mediated Annulation of α‐Aryl‐Substituted Carbonyl Compounds with Alkynes: A Simple and Highly Efficient Method for the Regioselective Synthesis of Polysubstituted Naphthalene Derivatives. (2004)

Abstract For Abstract see ChemInform Abstract in Full Text.
New detection method of hot-carrier degradation using photon spectrum analysis of weak luminescence on CMOS VLSI (1990)

A method developed to find the weakest transistor against hot-carrier-induced degradation by counting photon emission of various wavelengths in an operating VLSI circuit is presented. The method's underlying principle is that high-energy photons emitted from the transistors are caused by hot-carrier effects. The spectral distribution of photon energy emitted from n-channel MOSFETs is studied, and is found to follow the Maxwell-Boltzmann distribution. Photon emission with about 200 nm wavelength strongly correlates with hot-carrier-induced degradation. This method was applied to the static random access memory in a microprocessor. Transistors which are estimated to be seriously degraded by hot-carrier effect were detected. This method improves the reliability of VLSI circuits without long-term testing.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Preservation of myocardial function and metabolism at subzero nonfreezing temperature storage of the heart. (1996)

Storage in the intracellular type solution at subzero nonfreezing (-1 degree C) temperature as compared with 4 degrees C appears to prolong myocardial preservation with respect to the enhancement of postischemic functional recovery, preservation of myocardial adenine nucleotides during ischemia, and prevention of myocardial edema at reperfusion.
The effect of saline storage before replantation upon dry damage of the periodontal ligament (1986)

Abstract The effect of 30 min of saline storage before replantation of teeth, which had been dried out for 30 min, was studied in 10 Green Vervet monkeys ( Cercopithecus aethiops ). Maxillary central incisors were extracted and dried out for 30 min, after which 1 incisor was replanted and the other transferred to a saline solution for 30 min before replantation. No splinting or endodontic treatment was carried out. The teeth were examined after 8 wk. Histometric analysis showed identical extent of root resorption in the 2 groups, with ankylosis being the dominant resorption type, and with very limited pulpal repair in either group. It is concluded that saline storage under the experimental conditions chosen had no effect on development of root resorption or pulpal repair, presumably because 30 min dry storage had inflicted close to maximal damage on the periodontal ligament at the root surface. On the other hand, it is of clinical importance that a certain delay in the replantation procedure does not influence periodontal and pulpal healing, as long as the tooth is kept in saline storage. This suggests that replantation under these conditions can be reserved for dental professionals, rather than favoring immediate replantation by anyone ‘on‐the‐spot’.
Elimination of cyclic prefix of OFDM systems using filter bank based multicarrier systems (2008)

The challenges associated with the OFDM system are addressed. OFDM transmits redundancy in terms of Cyclic Prefix (CP), which decreases the spectral efficiency of the system. A pulse shaping filter for the OFDM systems is proposed to remove the constraint of CP. Also, transmit and receive filters in OFDM system suffer from poor frequency response because of the use of rectangular window function. The non-rectangular window based prototype filters are proposed for the transmitter and receiver end. The comparison of performance of OFDM system and the suggested filter bank based multicarrier systems is provided in terms of BER and the stop band attenuation of the constituent filters.
ChemInform Abstract: BIS(BORANE)‐CYCLENPHOSPHORANE: A STABLE ADDUCT IN WHICH TWO PHOSPHORUS(V)‐BONDED NITROGEN ATOMS DISPLAY DONOR CHARACTER (1983)

Abstract Cyclenphosphoran (I) reagiert mit zwei Äquivalenten BH 3 unter nahezu quantitativer Bildung des stabilen Bisaddukts (II), das 3′ P‐, "B‐ und 13 C‐NMR‐spektroskopisch charakterisiert wird.
Screening and Functional Analysis of TEK Mutations in Chinese Children With Primary Congenital Glaucoma (2021)

<b>Purposes:</b> Recent studies have suggested that loss-of-function mutations of the tunica intima endothelial receptor tyrosine kinase (TEK) are responsible for approximately 5% of primary congenital glaucoma (PCG) cases in diverse populations. However, the causative role of TEK mutations has not been studied in Chinese PCG patients. Here, we report the mutation spectrum of TEK after screening a large cohort of PCG patients of Chinese Han origin and analyze the identified variants in functional assays. <b>Methods:</b> TEK-targeted next-generation sequencing (NGS) was performed in 200 PCG patients. Candidate variants were prioritized by mutation type and allele frequency in public datasets. Plasmids containing wild type and identified variants of TEK were constructed and used to assess protein expression, solubility, receptor auto-phosphorylation, and response to ligand stimulation in cell-based assays. <b>Results:</b> Ten missense and one nonsense heterozygous variants were detected by NGS in 11 families. The clinical features of TEK variants carriers were comparable to that of TEK-mutated patients identified in other populations and CYP1B1-mutated individuals from in-house database. Functional analysis confirmed four variants involving evolutionarily conserved residues to be loss-of-function, while one variant (p.R1003H) located in tyrosine kinase domain seemed to be an activating mutation. However, our results did not support the pathogenicity of the other five variants (p.H52R, p.M131I, p.M228V, p.H494Y, and p.L888P). <b>Conclusion:</b> We provide evidence for TEK variants to be causative in Chinese PCG patients for the first time. Attention needs to be paid to TEK mutations in future genetic testing.
Etude de la dégradation à hautes températures de matériaux d'outils d'emboutissage vis-à-vis d'une tôle USIBOR 1500P revêtue AluSi: Quantification expérimentale de l’adhésion (2011)

International audience
Segmenting meetings into agenda items by extracting implicit supervision from human note-taking (2007)

Splitting a meeting into segments such that each segment contains discussions on exactly one agenda item is useful for tasks such as retrieval and summarization of agenda item discussions. However, accurate topic segmentation of meetings is a difﬁcult task. In this paper, we investigate the idea of acquiring implicit supervision from human meeting participants to solve the segmentation problem. Speciﬁcally we have implemented and tested a note taking interface that gives value to users by helping them organize and retrieve their notes easily, but that also extracts a segmentation of the meeting based on note taking behavior. We show that the segmentation so obtained achieves a Pk value of 0.212 which improves upon an unsupervised baseline by 45% relative, and compares favorably with a current state–of–the–art algorithm. Most importantly, we achieve this performance without any features or algorithms in the classic sense.
Modification of human placental alkaline phosphatase by periodate-oxidized 1,N6-ethenoadenosine monophosphate (1990)

Oxidation of 1,N6-ethenoadenosine monophosphate (epsilon AMP) with periodate cleaved the cis-diol of the ribose ring and resulted in the formation of a dialdehyde derivative (epsilon AMP-dial). At room temperature epsilon AMP-dial was unstable and underwent beta-elimination to give 4',5'-anhydro-1,N6-ethenoadenosine dialdehyde acetal (A epsilon Ado-dial). These nucleotide analogues were found to inactivate human placental alkaline phosphatase in a time- and concentration-dependent manner. epsilon AMP-dial was shown to be an affinity label for the enzyme on the basis of the following criteria. (a) Kinetics of the enzyme activity loss over a wide range of epsilon AMP-dial concentration showed a saturating phenomenon. Removal of the phosphate group made the reagent (A epsilon Ado-dial) become a general chemical modifying reagent. (b) The artificial substrate p-nitrophenyl phosphate gave substantial protection of the enzyme against inactivation. (c) epsilon AMP-dial was a substrate and a partial mixed-type inhibitor for the enzyme. Results of the inhibition and protection studies indicated that the reagent and substrate could combine with the enzyme simultaneously. Besides the phosphate-binding domain, an induced hydrophobic region is proposed for the substrate-binding site for human placental alkaline phosphatase.
Induction of cytoplasmic mannose-binding jacalin-related lectins is a common phenomenon in cereals treated with jasmonate methyl ester. (2004)

Treatment of whole plants with jasmonic acid methyl ester induces lectin activity in leaves of Oryza sativa, Hordeum vulgare, Triticum vulgare, Secale cereale and Zea mays. Purification and characterization of the lectins revealed that they all have a very similar molecular structure and carbohydrate-binding properties. Further analysis of the cDNA clones encoding the lectins revealed that they all belong to the family of cytoplasmic mannose-specific jacalin-related lectins.
Classification and Detection of Breathing Patterns with Wearable Sensors and Deep Learning (2020)

Rapid assessment of breathing patterns is important for several emergency medical situations. In this research, we developed a non-invasive breathing analysis system that automatically detects different types of breathing patterns of clinical significance. Accelerometer and gyroscopic data were collected from light-weight wireless sensors placed on the chest and abdomen of 100 normal volunteers who simulated various breathing events (central sleep apnea, coughing, obstructive sleep apnea, sighing, and yawning). We then constructed synthetic datasets by injecting annotated examples of the various patterns into segments of normal breathing. A one-dimensional convolutional neural network was implemented to detect the location of each event in each synthetic dataset and to classify it as belonging to one of the above event types. We achieved a mean F1 score of 92% for normal breathing, 87% for central sleep apnea, 72% for coughing, 51% for obstructive sleep apnea, 57% for sighing, and 63% for yawning. These results demonstrate that using deep learning to analyze chest and abdomen movement data from wearable sensors provides an unobtrusive means of monitoring the breathing pattern. This could have application in a number of critical medical situations such as detecting apneas during sleep at home and monitoring breathing events in mechanically ventilated patients in the intensive care unit.
Congestive heart failure secondary to gemcitabine nab-paclitaxel in patients with pancreatic cancer. (2014)

Based on review of literature, as far as we are aware of, this is the first report of congestive heart failure as an adverse effect of combination therapy. Both patients had evidence of diastolic dysfunction which may have predisposed them to cardiac toxicity secondary to gemcitabine plus nab-paclitaxel. The exact mechanism of action is currently unknown and requires further studies. However, it is imperative for physicians to be aware of this adverse effect and closely monitor patients with underlying heart disease who are undergoing treatment with gemcitabine plus nab-paclitaxel.
Hybrid dual-threshold design techniques for high-performance processors with low-power features (1997)

Article Free Access Share on Hybrid dual-threshold design techniques for high-performance processors with low-power features Authors: Uming Ko Texas Instruments Incorporated, P.O. Box 660199, M/S 8652, Dallas, Texas Texas Instruments Incorporated, P.O. Box 660199, M/S 8652, Dallas, TexasView Profile , Andrew Pua Texas Instruments Incorporated, P.O. Box 660199, M/S 8652, Dallas, Texas Texas Instruments Incorporated, P.O. Box 660199, M/S 8652, Dallas, TexasView Profile , Anthony Hill Texas Instruments Incorporated, P.O. Box 660199, M/S 8652, Dallas, Texas Texas Instruments Incorporated, P.O. Box 660199, M/S 8652, Dallas, TexasView Profile , Pranjal Srivastava Texas Instruments Incorporated, P.O. Box 660199, M/S 8652, Dallas, Texas Texas Instruments Incorporated, P.O. Box 660199, M/S 8652, Dallas, TexasView Profile Authors Info & Claims ISLPED '97: Proceedings of the 1997 international symposium on Low power electronics and designAugust 1997 Pages 307–311https://doi.org/10.1145/263272.263362Published:01 August 1997Publication History 11citation116DownloadsMetricsTotal Citations11Total Downloads116Last 12 Months10Last 6 weeks1 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF