gebhart/patrepeval huggingface dataset:
Characterization and functional analysis of laminin isoforms in human bone marrow (2000)

Laminins are a family of disulfide-linked heterotrimeric proteins consisting of 3 different subunits termed α, β, and γ chains. Combinations of 11 characterized laminin subunits (α1-α5, β1-β3, and γ1-γ3) generate at least 12 laminin isoforms, which can serve different functions. Although expression of laminin in the hematopoietic microenvironment has been known for many years, the nature of the laminin isoforms present in the human bone marrow is poorly characterized. The present study attempts to clarify this issue. Reverse transcriptase–polymerase chain reaction analysis of human bone marrow stromal cells suggested the expression of many laminin isoforms in the marrow. Northern blot and immunoblot analysis, however, showed that laminin-8/9 and laminin-10/11 are the most abundant laminin isoforms synthesized by human bone marrow stromal cells. Other isoforms, if present, certainly play a minor role in the hematopoietic microenvironment. Functionally, laminin-10/11 preparations showed strong adhesive interactions with human CD34+ cell lines. Antibodies against the β1 integrin subunit inhibited these interactions. Other laminin isoforms, especially laminin-1 and laminin-2/4, showed only weak or no adhesive interactions with the hematopoietic cell lines tested, explaining former negative results. In addition to its adhesion-mediating properties, laminin-10/11 preparations also showed a mitogenic activity for human hematopoietic progenitor cells. Taken together, these data suggest that laminin in the bone marrow plays a hitherto unexpected important function in the development of hematopoietic progenitor cells.
A multi-echelon integrated JIT inventory model using the time buffer and emergency borrowing policies to deal with random delivery lead times (2003)

This paper proposes a multi-echelon integrated just-in-time (JIT) inventory model with random delivery lead times for a serial supply chain in which members exchange information to jointly make purchase, production, and delivery decisions. The performance of the whole supply chain depends on whether or not uncertain delivery can be handled properly. In this paper, a time buffer and emergency borrowing policies are used simultaneously to deal effectively with random delivery lead times and to protect a JIT system against shortages of goods. To construct easily the proposed multi-echelon integrated JIT inventory (MEIJITI) model, a duplication methodology is created. Since optimizing the proposed model is equivalent to solving an extremely complex mixed nonlinear integer programming problem, three propositions used to reduce the solution space and simplify the solution procedure are derived. Accordingly, a proposed search method for finding the optimal solution and a simulated annealing algorithm used successfully to obtain a near-optimal solution are developed. Two phases of an experiment were conducted, and some important observations are drawn.
<title>An innovative system for formulating complex, combined content-based and keyword-based queries</title> (2003)

We propose a search & retrieval (S&R) tool, which supports the combination of a text search with content-based search for video and image content. This S&R system allows the formulation of complex queries allowing the arbitrary combination of content-based and text-based query elements with logical operators. The system will be implemented as a client/server system. The entire S&R system is designed in such a way that the client system can be either a web application accessing the server over the Internet or a native client with local access to the server. The S&R tool is embedded into a system called MECiTV - Media Collaboration for iTV. Within MECiTV a complete authoring environment for iTV content will be developed. The proposed S&R tool will enable iTV authors and content producers to efficiently search for already existing material in order to reduce costs for iTV productions.
On The Electromagnetic Theory Of Wire Gratings Used In The Infrared (1984)

In infrared technology, most of transmission gratings are used in the resonance domain (their spacing is of the same order that the wavelength of the incident light). Under such circumstances, the polarization takes a prominent part in the determination of the efficiencies. We have to take into account the vectorial character of light and therefore we must abandon the scalar theories of Optics to use electromagnetic theories derived from Maxwell equations. In other words, there is a need for efficient numerical techniques capable of solving rigorously the problem of perfectly conducting wire gratings. The approximate methods proposed by Marcuwitz in the Waveguide Handbook (Mac Graw Hill, New York, 1951) seem now unable to answer all the questions the experimenters asked for. In this paper we report on two completely different methods called H.M. (Hamiltonian method) and B.F.M. (Bessel function method) that we have recently implemented on a IBM 3081 computer.
Characterization of a Pulsed Glow Discharge Laser Ablation System Using Optical Emission (2000)

Investigations involving laser-based sampling of copper into an auxiliary pulsed glow discharge for ionization and excitation are presented. The interaction of the ablated copper with the auxiliary glow discharge was studied by monitoring the copper atom emission signal at 368.744 nm. Results demonstrate the ability to time ablation appropriately to access specific temporal regions of the pulsed plasma. More specifically, laser-ablated material was introduced into the glow discharge negative glow during the afterpeak. Ionization and excitation was accomplished by collisions with a metastable argon population produced by the glow discharge (Penning ionization) followed by recombination to yield excited-state Cu atoms. The work presented investigates parameters that affect the atomic emission signal intensity of the ablated material, including cathode-to-target distance, discharge gas pressure, and relative timing of discharge and ablation. Results demonstrate that decreasing the glow discharge working gas pressure increases the transport efficiency of laser-ablated material into the negative glow. These investigations are part of an ongoing series of studies on sample introduction schemes that utilize different ionization and excitation mechanisms found in pulsed glow discharge plasmas.
Circuits et systèmes asynchrones: une approche architecturale (2005)

International audience
Advanced vibration suppression algorithms in adaptive optics systems (2012)

Vibration suppression in astronomical adaptive optics (AO) systems has gathered great attention in the context of next-generation instrumentation for current telescopes and future Extremely Large Telescopes. Laser tomographic AO systems require natural guide stars to measure the low-order modes such as tip-tilt (TT) and TT-anisoplanatism. To increase the sky coverage, the guide stars are often faint, thus requiring lower temporal sampling frequencies to work on a more favorable signal-to-noise regime. Such sampling frequencies can be of the order of, or even lower than, the range of frequencies where vibrations are likely to appear. Ideally, vibrations affecting the low-order modes could be corrected at the higher laser loop frame rate using an upsampling procedure. This paper compares the most relevant solutions proposed hitherto to a novel multirate algorithm using the linear-quadratic-Gaussian (LQG) approach capable of upsampling the correction to further reduce the impact of vibrations. Results from numerical Monte Carlo simulations span a large range of parameters from pure sinusoids to relatively broad peak vibrations, covering the likely-to-be signals in a realistic AO system. The improvement is shown at sampling frequencies from 20 to 800 Hz, including below the vibration itself, in the example of 29.5 Hz on a Thirty Meter Telescope-like scenario. The multirate LQG ensures the least residual for both faint and bright stars for all the peak widths considered based on telemetry from the Keck Observatory.
Performance limits for FDMA cellular systems described by hypergraphs (1991)

The authors present some preliminary material about hypergraphs, including a discussion of what they call random hypergraph multicolorings, a notion which is central to the analysis of frequency-assignment algorithms. They show that for any frequency-assignment algorithm, the carried traffic function must satisfy T(r)&amp;les;T_0(r), where T_0(r) is a simple function that can be computed by linear programming. They give an asymptotic analysis of a class of 'fixed' frequency-assignment algorithms, and show that in the limit as n→∞, these algorithms achieve carried traffic functions that are at least as large as T_1( r), another simple function that can be computed by linear programming. They show that T_0(r)=T_1(r). This common value, denoted by T_(H,p)(r) is the function referred to above. They also describe some of the most important properties of the function TH,p(r), and identify the 'most favorable' traffic patterns for a given hypergraph H.
Data acquiring support system using recommendation degree map for 3D outdoor modeling (2007)

We propose a support system of range data acquisition by a laser rangefinder for wide area outdoor modeling in order to reduce un-observed portions of generated model. The system presents the operator a recommendation degree map which illustrates recommendation position of acquisition of range data in the objective area. The operator decides a next acquisition position in consideration of movement distance of sensor system and recommendation degrees of the map. The recommendation degree is computed by measurement density as the index. The recommendation degree at a position is given by the difference between measurement density acquired by rangefinder and measurement density estimated by the system in reachable area of the laser beams. The reachable area of the laser beams is estimated by using a 3D model generated from the acquired range data. The system computes the measurement density by the reachable area of the laser beams. The recommendation degrees in the objective area are computed by the model generated from range data whenever a range data is acquired. Moreover, the system judges whether overlapping portions of the range data can be acquired for the registration by ICP algorithm from a work area which the sensor system can enter.
Exfoliation methods for compositional and electronic characterization of interfacial Mo(Se x ,S y ) in Cu(In,Ga)(Se,S) 2 solar cells by X‐ray and UV photoelectron spectroscopy (2022)

Mo(Se x S y ) is a transition metal dichalcogenide typically applied as a back contact interlayer in Cu(In,Ga)(Se,S) 2 (CIGSSe) solar cells. Band alignment at the buried Mo/CIGSSe junction mediated by Mo(Se x S y ) is important for current transport and enables quasi‐ohmic behavior between the CIGSSe absorber and the Mo back electrode. Furthermore, the S/(Se + S) ratio is a crucial parameter that determines the height of the valence band offset at the CIGSSe/Mo(Se x S y ) interface. Because the interlayer is formed during rapid thermal processing, an MoSe 2 or MoS 2 thin film grown on free substrate surfaces will not be representative for a realistic solar cell device. Thus, for fundamental thin‐film material analysis, as well as functional characterization and modeling, appropriate preparation and analytical techniques are required in order to prevent artifacts. In principal, the weak van der Waals forces between two‐dimensional stacked Mo(Se x S y ) sheets allow the implementation of exfoliation procedures to generate free Mo(Se x S y ) surfaces out of CIGSSe solar cell layer stacks. In this article, two different exfoliation‐based Mo(Se x ,S y ) preparation methods are investigated and evaluated with respect to subsequent surface analytical characterization by X‐ray and ultraviolet photoelectron spectroscopy. A special focus is laid on an artifact‐free characterization of chemical and electronical properties of the exposed layers for a number of samples. In a first instance, the compositional Se/S and (Se + S)/Mo ratios at the surface are quantitatively analyzed on the basis of dedicated peak‐fitting routines. Artifacts from carbonaceous contamination due to different exfoliation glues can be prevented through a detailed comparative analysis of carbon 1s and KLL Auger peaks. Furthermore, a significant surface band bending is observed that can be reduced by low‐energy Ar ion in situ sputtering. A simple model for the sputter removal of a charged surface layer is presented, which allows to approximately calculate the absolute valence band maximum (VBM) positions required for band alignment and numerical device simulations. The presented exfoliation surface analysis methodology is important for the whole CIGS(Se) solar cell community and may be of general interest for emerging applications of further 2D transition metal dichalcogenides as well.
Adjoint tomography of the Italian lithosphere (2022)

Abstract The evolution and state of geological structure at Earth’s surface is best understood with an accurate characterization of the subsurface. Here we present seismic tomographic images of the Italian lithosphere based on ground motion recordings and characterized by compressional and shear wavespeed structure at remarkable resolution, corresponding to a minimum period of ~10 s. Enhanced accuracy is enabled by state-of-the-art three-dimensional wavefield simulations in combination with an adjoint-state method. We focus on three primary findings of our model Im25. It highlights the distribution of fluids and gas (CO 2 ) within the Italian subsurface and their correlation with seismicity. It illuminates Mt. Etna volcano and supports the hypothesis of a deep reservoir (~30 km) feeding a shallower magma-filled intrusive body. Offshore of the eastern Italian coast, it reveals that the Adriatic plate is made of two distinct microplates, separated by the Gargano deformation zone, indicating a complex lithosphere and tectonic evolution.
Tungsten deposition on porous silicon for formation of buried conductors in single crystal silicon (1986)

We report measurements of the kinetics of tungsten metallization of porous silicon layers for the formation of buried conductors under single crystal silicon. The kinetics depend markedly on the partial pressure of the source gas and on the degree of porosity, in agreement with a proposed model in which the rate-limiting step is diffusion of WF6 source gas through the narrow pore channels. Preliminary results are presented of the full isolation of silicon islands by buried metal.
Taql RFLP in human adenylate kinase-1 (AK1) gene region on chromosome 9 (1989)

PROBE:3 3.25 kb BamHI fragment (hAK1B3.25) spanning exon 2 to exon 5 of the adenylate kinase-1 gene was derived from a human genomic clone (lambda hAK1-1, kindly provided by Dr. A. Nakazawa) isolated from Maniatis' library.
Does Current Training in Radiation Oncology Prepare Radiation Oncologists to Optimally Manage Patients With Head and Neck Cancer? (2023)

Richmon, Jeremy D. MD; Chan, Annie W. MD; Sadow, Peter M. MD, PhD; Wirth, Lori J. MD; Goldsmith, Tessa MA CCC-SLP; Juliano, Amy F. MD; Wallner, Paul DO; Quon, Harry MD Author Information
Plasma Concentration of C-Reactive Protein and Risk of Developing Peripheral Vascular Disease (1998)

These prospective data indicate that among apparently healthy men, baseline levels of CRP predict future risk of developing symptomatic PAD and thus provide further support for the hypothesis that chronic inflammation is important in the pathogenesis of atherothrombosis.
Codiagnosability Analysis of Bounded Petri Nets (2017)

In this paper, we propose a novel approach to perform codiagnosability analysis of labeled bounded Petri nets. A set of sites observe the system evolution, each one with its own observation mask. Sites do not exchange information with each other but communicate with a coordinator. The coordinator is able to detect a fault if and only if at least one site is able to do that. In a previous work by some of us, it has been proven that a necessary and sufficient condition for codiagnosability under such a framework is the absence of sequences that are “ambiguous” with respect to all sites and whose length may grow indefinitely after the occurrence of some fault. The novelties of the approach consist in using the notion of basis markings to avoid exhaustive enumeration of the set of reachable markings, and in the construction of an automaton, called Verifier, that allows one to detect the presence of ambiguous sequences. Finally, we introduce the notion of K-codiagnosability: a system is K-codiagnosable if and only if faults can be detected in the above framework within at most K observations after their occurrence. An algorithm is provided to compute the smallest value of K such that the system is K-codiagnosable.
Reducing routing table computation cost in OSPF (2003)

In a link state protocol, every router has complete topology information about the network. We argue that with such information, divide-and-conquer schemes can be used to make the protocol processing more efficient. As an example, we present a simple approach for a router running the Open Shortest Path First (OSPF) protocol to automatically detect if its interfaces lead to multiple disjoint regions within an OSPF Area. If such disjoint regions exist, this approach can make the routing table computation more efficient. Compared to OSPF, this approach can reduce the computation work by more than n times in ideal cases, where n is the number of disjoint Within Area Routing Regions (WARRs). Furthermore, route computations in different WARRs are independent and can be done in parallel to give an additional speedup of min(n-1, m), where m is the number of CPUs in the router. The correctness of the algorithm is illustrated. The implementation of this approach is very simple and requires no change to OSPF. This approach is especially suitable for routers in corporate networks and can be immediately applied to current routers.
Do all cardiac surgery patients benefit from antifibrinolytic therapy ? (2021)

This is the first description of the prevalence of three different fibrinolytic phenotypes and their potential influence on cardiac surgery patients. The use of AF was associated with increased morbidity, but because of the small sample size and treatment allocation bias, additional confirmatory studies are necessary. We hope these present findings open the dialog on whether it is safe to administer AFs to cardiac surgery patients who are normo- or hypofibrinolytic.
Temporal evolution of Arctic sea-ice temperature (2001)

Abstract Vertical profiles of temperature from the air through the snow and ice and into the upper ocean were measured over an annual cycle, from October 1997 to October 1998, as part of a study of the Surface Heat Budget of the Arctic Ocean (SHEBA). These observations were made at nine locations, including young ice, ponded ice, undeformed ice, a hummock, a consolidated ridge and a new blocky ridge. All of the sites had similar environmental forcing, with air temperatures at the different sites typically within 1°C. In general, the seasonal evolution of ice temperature followed a pattern of (1) a cold front propagating down through the ice in the fall, (2) cold ice temperatures and ice growth in late fall, winter and early spring, and (3) warming to the freezing point in the summer. Within this general pattern, there was considerable spatial variability in the temperature profiles, particularly during winter. For example, snow/ice interface temperatures varied by as much as 30°C between sites. The coldest ice temperatures were observed in a consolidated ridge with a thin snow cover, while the warmest were in ponded ice. The warm pond temperatures were a result of two factors: the initial cooling in the fall was retarded by freezing of pond water, and the depressed surface of the pond was quickly covered by a deep layer of snow (0.6 m). In an 8 m thick unconsolidated ridge, the cold front did not penetrate to the ice bottom during winter, and a portion of the interior remained below freezing during the summer. The spatial variability in snow depth and ice conditions can result in situations where there is significant horizontal transport of heat.
Computational basis of decision-making impairment in multiple sclerosis (2021)

Decision-making deficits in MS patients could be described by the interplay between latent computational processes, neurocognitive impairments, and mood/motivational symptoms.
Totalsynthese des cyclischen Depsipeptids Vioprolid D über sein (Z)‐Diastereomer (2020)

Abstract Die erste Totalsynthese von Vioprolid D wurde ausgehend von (2 S )‐3‐Benzyloxy‐2‐hydroxypropansäuremethylester in einer Gesamtausbeute von 2.0 % erreicht (16 Stufen in der längsten linearen Sequenz). Das cyclische Depsipeptid wurde aus zwei Bausteinen von ähnlicher Größe und Komplexität in einem modularen, hoch konvergenten Ansatz zusammengesetzt. Die Bildung einer Peptidbindung an der C‐terminalen Dehydrobutyrin‐Aminosäure des nördlichen Fragments war über sein ( Z )‐Diastereomer möglich. Nach der Makrolactamisierung und der Bildung des Thiazolinrings wurde die ( Z )‐Doppelbindung der Dehydrobutyrin‐Einheit zur ( E )‐Doppelbindung des Naturstoffs isomerisiert. Die Cytotoxizität von Vioprolid D ist signifikant höher als die seines ( Z )‐Diastereomers.
A Design of Cloud-Based Billing and Monitoring System for an Electric Company (2018)

Purpose -This descriptive study developed a cloud-based billing and monitoring system for an electric company named Quezelco1. The developed system was implemented in a web-based environment using a third party cloud infrastructure. After the development, the study gathered feedback from both end-users and technical experts to evaluate the proposed system in terms of content, functionality, reliability, maintainability, and features. Their comments and suggestions on the proposed system were also gathered.
Systematic design study of an all-optical delay line based on Brillouin scattering enhanced cascade coupled ring resonators (2010)

We present a technique to improve the slow-light performance of a side-coupled spaced sequence of resonators (SCISSOR) combined with a stimulated Brillouin scattering (SBS) gain medium in optical fiber. We evaluate device performance of SCISSOR-only and SCISSOR + SBS systems for different numbers of cascaded resonators from 1 to 70 using two different data fidelity metrics including eye-opening and mutual information. A practical system design is demonstrated by analyzing its performance in terms of fractional delay, power transmission, and data fidelity. We observe that the results from the two metrics are in good agreement. Based on system optimization under practical resource and fidelity constraints, the SCISSOR consisting of 70 cascaded resonators provides a fractional delay of 8 with 22 dB attenuation at a signal bit rate of 10 Gbps. The combined optimal SCISSOR (with 70 resonators) + SBS system provides a improved fractional delay up to 17 with unit power transmission under the same constraints.