gebhart/patrepeval huggingface dataset:
JCD Editorial March 2019 (2019)

Welcome to the March 6, 2019, edition of the JCD—your go-to journal for the cosmetic dermatologist. We are on a quest to be the best journal we can be, and with your help, we can accomplish this goal. We are always looking for the best papers on cosmetic, esthetic, and dermatologic surgery. If you are working on clinical trials, we want your articles. If you are reviewing a subject that would be of interest, we want your articles. If you have an original contribution, send it our way. We are also always looking for great reviewers. If you feel that you can contribute in this endeavor, send us a note and your CV. We will see about adding you to our roster, which ultimately helps us and your career. This issue has some amazing review articles that I would like to mention here. It starts with Majdič et al whose review the “Effectiveness and Safety of Hyaluronic Fillers Used to Enhance Overall Lip Fullness: A Systematic Review of Clinical Studies.” This is an important article and one that will surely be used by all who use HA fillers in the lip area. Next, we have an article by Baudoin entitled “A Comprehensive Guide to Upper Lip Aesthetic Rejuvenation.” Again, lips are a crucial part of what esthetic physicians treat. This article highlights another important part of what we need to know, when we treat patients in this region. We follow this with Wang et al and their article “Efficacy and Possible Mechanisms of Botulinum Toxin Treatment of Oily Skin.” The uses for botulinum toxin have expanded greatly over the years. We have heard more and more about using botulinum toxin for the treatment of oily skin, for the treatment of acne, and for the treatment of rosacea. In this article, we learn more about how this might work for oily skin and sebum reduction for our patients. We continue with our reviews with an article by Filoni on “Melasma: How Hormones Can Modulate Skin Pigmentation.” Pigmentation and its treatment is so prevalent that we hope this article stimulates the conversation further. Finally, Rani presents “Variables that Predict Response of Nevus of Ota to Lasers,” another important article as we continue to see this entity. We need to understand the best ways to approach it with our lasers and light sources. As you see, the JCD has things for everyone. There are amazing articles that follow the reviews on Injectables, Energy Based Devices, Chemical Peels, Dermatologic Surgery, Skin Care, and Basic Sciences. We hope you enjoy this issue of JCD and remember, send us your articles. If you would like to get involved, let us know.
3D Integrated Physics Package using MEMS Alkali Vapor Cell for Miniature Atomic Clocks (2019)

The 3D integration of MEMS alkali vapor cell for physics package of atomic clocks with function of thermal management and magnetic field control are presented. The physics package consists of MEMS alkali vapor cell, vertical-cavity surface-emitting laser (VCSEL), photo-diode and c-field coil. For thermal management, MEMS heaters and resistance temperature detectors (RTDs) are integrated into MEMS vapor cell and VCSEL subsystem. In order to integrate the MEMS vapor cell, VCSEL, photo-diode, each sub-system is mounted on the flexible substrate and they are 3-dimensionally integrated and interconnected by folding of flexible substrate. The Helmholtz coil and mu-metal foil are also embedded into physics package for magnetic field control. The integrated physics package is attached on ceramic substrate using solder-ball based inter-connection and sealed by using KOVAR lid and preform. The prototype of chip-scale physics for MEMS atomic clocks has a volume of 1 cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> and results in power consumption of 150 mW and stability of 2.2×10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-10</sup> @ 10s.
Ask Your Neurons: A Neural-Based Approach to Answering Questions about Images (2015)

We address a question answering task on real-world images that is set up as a Visual Turing Test. By combining latest advances in image representation and natural language processing, we propose Neural-Image-QA, an end-to-end formulation to this problem for which all parts are trained jointly. In contrast to previous efforts, we are facing a multi-modal problem where the language output (answer) is conditioned on visual and natural language input (image and question). Our approach Neural-Image-QA doubles the performance of the previous best approach on this problem. We provide additional insights into the problem by analyzing how much information is contained only in the language part for which we provide a new human baseline. To study human consensus, which is related to the ambiguities inherent in this challenging task, we propose two novel metrics and collect additional answers which extends the original DAQUAR dataset to DAQUAR-Consensus.
Biomechanical comparison of bioabsorbable sutureless screw anchor versus suture anchor fixation for rotator cuff repair (2005)

This bioabsorbable anchor may not provide sufficient fixation for rotator cuff repair in humans.
Analysis and implementation of multi-protocol gigabit Ethernet switch for real-time control systems (2021)

Deterministic data exchange over Ethernet network is used for real-time control applications such as programmable logic control and multi-axis motor control. Digitization of the production system asks for more Ethernet based devices. Machine vision sensors and collaborative robots require different set of network parameters. Therefore a faster communication network at gigabit speed and a converged network supporting different traffic types are needed. Time Sensitive Network (TSN) defines the capability to support converged network in cyber physical production systems. In addition, real-time Ethernet is used in closed applications such as robotics, machine tools and industrial backplane. In this paper we introduce flexible gigabit Ethernet switch architecture for open and closed control systems. We discuss firmware implementations for different protocols such as Profinet Conformance Class D and provide performance data for network parameters and real-time control parameters.
Genetic Diversity of Campylobacter jejuni Isolates from Farm Animals and the FarmEnvironment (2003)

The genetic diversity of Campylobacter jejuni isolates from farm animals and their environment was investigated by multilocus sequence typing (MLST). A total of 30 genotypes, defined by allelic profiles (assigned to sequence types [STs]), were found in 112 C. jejuni isolates originating in poultry, cattle, sheep, starlings, and slurry. All but two of these genotypes belonged to one of nine C. jejuni clonal complexes previously identified in isolates from human disease and retail food samples and one clonal complex previously associated with an environmental source. There was some evidence for the association of certain clonal complexes with particular farm animals: isolates belonging to the ST-45 complex predominated among poultry isolates but were absent among sheep isolates, while isolates belonging to the ST-61 and ST-42 complexes were predominant among sheep isolates but were absent from the poultry isolates. In contrast, ST-21 complex isolates were distributed among the different isolation sources. Comparison with MLST data from 91 human disease isolates showed small but significant genetic differentiation between the farm and human isolates; however, representatives of six clonal complexes were found in both samples. These data demonstrate that MLST and the clonal complex model can be used to identify and compare the genotypes of C. jejuni isolates from farm animals and the environment with those from retail food and human disease.
Direct observation of grain orientation in YBa2Cu3O7-δthin films (1990)

Abstract Using a recently developed specimen-preparation technique to examine heteroepitactic growth in ceramics, the early development of grain orientation in thin YBa2 Cu3 O7-δ films prepared by pulsed-laser ablation can be determined. The technique involves deposition directly on to a specially prepared electron-transparent substrate. The films are examined during the early stages of growth by transmission electron microscopy. Three different orientations corresponding to different alignments of the c axis of the YBa2 Cu3 O7-delta; unit cell with the MgO substrate could be determined from the particle morphology in the image, but were not detected by selected-area diffraction due to their small size.
Graphical interfaces for cooperative planning systems (2002)

Enroute flight planning (selecting alternate routes or destinations due to unanticipated weather, traffic, malfunctions, etc.) is being used as the context for studying the design of cooperative problem-solving systems. A testbed, Flight Planner, for studying computer aids for enroute flight path planning, is described. Its design is based on a cognitive task analysis of five airline flight crews in a simulator study. The testbed runs on a Macintosh II controlling three color monitors, and is being used to study the design of supports for both flight crews and dispatchers. Some of the design concepts being studied in this environment are discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Влияние дефектов на поглощение терагерцового излучения в монокристалле CdSiP-=SUB=-2-=/SUB=- (2020)

Measurements of the transmission and reflection spectra of a CdSiP2 single crystal, performed in the temperature range from 80 to 300 K using pulsed terahertz and infrared Fourier spectroscopy, revealed a significant impact of post-growth defects on absorption in the THz range. It was found that this absorption is weakly dependent on temperature, in contrast to the previously obtained results for another crystal of the chalcopyrite family with s significantly lower concentration of defects. When cooling, the intrinsic absorption mechanisms were minimized and the contribution of defects to absorption was extracted
Purification and Properties of Apple Fruit Malic Enzyme (1966)

Malic enzyme was isolated and purified from mature apple fruits (Malus sylvestris, Miller) by utilizing procedures probably applicable to other soluble enzymes in this and similar tissues.The physical properties of apple fruit malic enzyme are similar to those reported for malic enzyme from other plant and animal sources. It is specific for l-malate, TPN and requires a divalent cation for activity. In contrast to the pigeon liver enzyme, supplemental TPN is not required for oxalacetic decarboxylase activity of the fruit enzyme. The pH optimum of the malic enzyme varied with the l-malate concentration and the nature of the divalent cation present. d-Malate activated the oxidation of l-malate at rate-limiting concentrations.
Comment on “Renewable energy liberation by nonthermal intermolecular bond dissociation in water and ethanol” [J. Appl. Phys. 109, 034908 (2011)] (2012)

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UWB low profile antennas using ferrite loaded GP (2008)

Wideband antennas that can operate over a frequency range from 10’s of MHz up to several GHz is highly desirable, yet a challenge [1–2]. As expected, a major challenge is to keep the size small while maintaining bandwidth. Another and key challenge is the need for a ground plane that does not deteriorate the UWB performance for conformal installations [2]. This paper is based on the design of an UWB ground plane using commercially available ferrite layer coating.
Impact of Ferroelectric Wakeup on Reliability of Laminate based Si-doped Hafnium Oxide (HSO) FeFET Memory Cells (2020)

The impact of the ferroelectric (FE) wakeup phenomenon on the reliability of fluorite structure-based laminated Si-doped hafnium oxide (HSO) FeFET memory cells is reported. The post wakeup cycling shows a strong change in the optimal program/erase (PG/ER) write conditions. A shift towards lower PG/ER switching conditions at a higher memory window (MW) is observed after wakeup cycling. Similarly, the cross wafer statistics for different FeFET dimensions shows a strong wakeup influence towards a lower variability and higher MW after wakeup. For the wakeup cycling different trends for amplitude and pulse width variation are observed. The increase in write pulse amplitude has limited impact whereas the number of wakeup cycles appears to be the driving factor. On the contrary, the write pulse width sweep (50-800ns) shows faster wakeup as the pulse width increases even on pristine devices. The FeFET area sweep shows a comparable wakeup behavior with a trend of higher shift window on larger devices. The high-temperature operation shows an initially lower MW and pronounced wakeup effect. On the other hand, the pyroelectric effect dominates at lower temperatures and leads to initially higher MW with an insignificant wakeup. The various factors associated with the FE wakeup effect are studied with insight into the changes in FeFET stack physics during wakeup cycling.
Design des ORCA-Moduls der OCEAN-Studie (2016)

A thorough assessment of SD-OCT images during anti-VEGF therapy provides the basis for the best possible needs-oriented treatment regimen. The control of the quality of data from daily routine practice may indicate possible weaknesses allowing explicit training and therefore optimization of patient treatment.
Additional file 2 of Combining phylogenetic footprinting with motif models incorporating intra-motif dependencies (2017)

Sequence data. This archive contains data files of alignments of the ChIP-seq positive regions and negative control regions for each of the 35 TFs in FASTA format. (ZIP 83763.2 kb)
Design of asynchronous RISC CPU register-file Write-Back queue (2015)

This paper presents the comparison results of Area, Performance and Power of FIFO and Data-Queue on a logically determined Null Convention Logic RISC CPU register file Write-Back circuit. A shift register block implemented using Delay-Insensitive techniques operates in a way that is identical to a FIFO. In this paper, we illustrate the architectures of the Delay-Insensitive Asynchronous Data-Queue and FIFO and analyze the characteristics of these circuits. This comparison results can be also used to the other buffering unit of the CPU such as scoreboard for Dynamic scheduling or Cache Controller memory interface circuits.
Physical and chemical modifications of lipid structures to inhibit permeation of free radicals in a supported lipid membrane model (2012)

Oxidation of encapsulated bioactives in lipid-based nanostructures (e.g., emulsions, liposomes and lipid coatings) is a significant challenge that limits functionality and shelf life of products in many industries including food, cosmetic, and pharmaceutical industries and in biomedical devices. The objective of this study is to investigate how physical and chemical properties of the lipid interface can be engineered to inhibit permeability to environmental free radicals. A glass-supported lipid membrane system is used to model the water–lipid interface. Peroxyl radicals generated in the aqueous phase permeate the supported membrane structure and react with an embedded lipid peroxidation sensor. By using epifluorescence microscopy to monitor the rate of fluorescence decay of the lipid sensor, various physical and chemical modifications of the supported membrane can be compared quantitatively. Physical properties tested include lipid composition (gel phase vs. fluid phase and addition of cholesterol) and a double membrane structure formed via layer-by-layer assembly. Chemical properties include direct addition of antioxidant molecules to either the lipid membrane or the aqueous phase. Results show that increasing molecular order of lipid membranes (with cholesterol or long-chain phospholipids) or assembling an additional protective membrane reduces the rate of permeation of free radicals by a small amount (approximately two-fold with respect to the reference membrane). The results also demonstrate that localization of chemical antioxidants at the lipid interface is an order of magnitude more effective in suppressing membrane permeation of free radicals than either aqueous phase antioxidants or any of the tested physical modifications.
Effects of Selective and Nonselective Alpha-1 -Adrenoceptor Antagonists on Intraurethral and Arterial Pressures in Intact Conscious Dogs (1996)

In this study, we used a novel conscious dog model to evaluate the uroselectivity of selected alpha 1-antagonists either approved for human use or in clinical development for the treatment of symptomatic benign prostatic hyperplasia (BPH) and compared those results to their in vitro binding and functional affinities at alpha 1A, alpha 1B and alpha 1D receptor subtypes. Conscious dogs were instrumented acutely with a balloon catheter for the measurement of changes in prostatic intraurethral pressure (IUP) and chronically with implantable telemetry devices for the measurement of arterial pressure. The pressor effects of the alpha 1-agonist phenylephrine (PE) on IUP and mean arterial pressure (MAP) were compared before and at various time points after oral doses of either terazosin, doxazosin, tamsulosin or Rec 15/2739 (SB 216469). At submaximal doses, terazosin and doxazosin blocked PE-induced increases in MAP to a greater extent than increases in IUP. Tamsulosin blocked both parameters equally at the lowest and highest doses; however, at the intermediate dose, IUP was blocked more than MAP. Rec 15/2739 at each dose always blocked IUP to a greater extent than MAP. While the in vivo uroselectivity of these agents was predicted by radioligand binding and in vitro functional selectivity for the alpha 1A subtype over alpha 1B and alpha 1D subtypes, results from conscious dog experiments indicate that estimates of in vivo uroselectivity also depend upon dose and the time after administration. Our conscious canine model provides the basis for frequent and repeated evaluation of uroselectivity parameters over many hours, thus providing a pharmacological profile of compound effects perhaps more relevant to clinical practice.
Vulnerability Analysis and Attacks on NFC-Enabled Mobile Phones (2009)

Near Field Communication (NFC)-enabled mobile phones and services are starting to appear in the field, yet no attempt was made to analyze the security of NFC-enabled mobile phones. The situation is critical because NFC is mostly used in the area of payment and ticketing. This paper presents our approach to security testing of NFC-enabled mobile phones. Our approach takes into account not only the NFC-subsystem but also software components that can be controlled through the NFC-interface. Through our testing approach, we were able to identify a number of previously unknown vulnerabilities, some of which can be exploited for spoofing of tag content, an NFC-based worm, and for denial-of-service attacks. We further show that our findings can be applied to real world NFC-services.
Comparison of Weight-Loss Diets With Different Compositions of Fat, Protein, and Carbohydrates (2009)

Types of diet used for treating overweight people include those that emphasize protein, those that emphasize carbohydrates, or those that emphasize fat. There is considerable controversy about which is most effective. This randomized clinical trial compared the effects on the body weight of overweight individuals of 4 energy-reduced diets that differed in their targeted percentage of macronutrients. A total of 811 overweight adults aged 50 to 52 years were randomized to receive to 1 of 4 diets containing fat, protein, and carbohydrates in the following proportions: 20%, 15%, and 65% (group 1, n = 204); 20%, 25%, and 55% (group 2, n = 202); 40%, 15%, and 45% (group 3, n = 204); and 40%, 25%, and 35% (group 4, n = 201). Each diet contained similar foods. Individual and group instructional sessions were offered to the participants. At 6 months, participants in each group had a mean weight loss of 6 kg (7%) of their initial weight. After 12 months, all groups slowly regained body weight. The amount of weight loss was similar after 2 years among participants assigned to a diet containing 15% or 25% protein (3.0 and 3.6 kg, respectively; among those assigned a diet of 40% or 20% fat (3.3 kg for each); and in those assigned to a diet with 65% or 35% carbohydrates (2.9 and 3.4 kg, respectively) (P > 0.20 for all comparisons). The average weight loss among the 80% of participants who completed the trial was 4 kg and at least 10% of initial body weight was lost in 14% to 15% of the participants. At 2 years, there were no differences among the diets in satiety, hunger, diet satisfaction, and attendance at group sessions. A strong association was found between attendance and weight loss. Risk factors for cardiovascular disease and diabetes were reduced by all the diets. These findings show that reduced-calorie diets that emphasize a range of fat, protein, and carbohydrate compositions are equally beneficial in producing clinically meaningful weight loss and the maintenance of weight loss over 2 years.
Multi-level Analog Programmable Graphene Resistive Memory with Fractional Channel Ferroelectric Switching in Hafnium Zirconium Oxide (2022)

This paper reports multi-level programming of ferroelectrically modulated resistive memory in two-dimensional atomically thin graphene. The ferroelectric film utilized is hafnium zirconium oxide (HZO). The device uses a graded potential across the graphene resistor for fractional ferroelectric switching of the underlying HZO, which in turn produces an analog modulation of graphene resistance. A multi-level modulation of 13.3% was achieved in a graphene resistor of 22 k&#x03A9; nominal resistance, with programming voltages from 0 to 8.5 volts to achieve symmetric and asymmetric programming of up to 31 distinct resistive levels of memory. This device has potential of storing analog values for neuromorphic computing. The device architecture constitutes a thickness of ~20nm, which allows for high spatial density integration and aggressive voltage scaling.
An Efficient and Stable Hydrophobic Molecular Cobalt Catalyst for Water Electro-oxidation at Neutral pH (2016)

The synthesis of a library of molecular water oxidation catalysts based on the Co complex of tris(2-benzimidazolylmethyl)amine is described. Hydrophobicity was identified as the key variable in mediating the catalytic competence of the complexes. The change in this parameter correlates with both the conformational mobility of the ligand core and the structural changes in the local solvent environment around the metal site. The optimal Co complex identified is hydrophobic, because of three semifluorinated side chains. It catalyzes water electro-oxidation efficiently at neutral pH, with an overpotential of 390 mV and a turnover frequency (TOF) of 1.83 s–1 in the absence of soluble Co salts. The catalyst can be immobilized through physisorption, and it remains stable in prolonged electrolysis experiments.
Nanotechnologies and microchips in genetic diseases (2003)

Microarrays or microchips represent a new area of high technology, which will completely change the methodological approach to basic research and clinical diagnostics. This technology can be used for genotyping, expression profiling and proteome analysis. Genetics and molecular medicine have an expanding need for rapid genotyping, mutational analysis and DNA re-sequencing technologies, i.e. microarrays that have a clear potential for miniaturization, parallelization, and automation and enable high-throughput screening. Expression profiling technology is a new tool for investigating expression patterns, identifying new disease genes either for monogenic disorders or for complex traits, identifying new functional and cellular relationships and identifying new pathways and possible related drugs. This technology has been successfully applied to the study of complex traits, i.e. cardiovascular diseases, cancer and type II diabetes, providing new insights into possible pathogenetic mechanisms and new therapeutical approaches. Finally, microarray can further improve proteome analysis. This review discusses these points.