gebhart/patrepeval huggingface dataset:
Effect of different doses of aluminium hydroxide on renal deterioration and nutritional state in experimental chronic renal failure. (1991)

To investigate the effects of aluminium hydroxide (AH), a phosphate binder, on the progress of chronic renal diseases, high doses (9.6 g/kg/day, group ADR-H), moderate doses (2.4 g/kg/day, group ADR-M), and low doses (1.2 g/kg/day, group ADR-L) of the compound, were orally administered for 34 weeks to rats with Adriamycin (ADR)-induced focal glomerular sclerosis. Serum creatinine and blood urea nitrogen were significantly lower in either group ADR-H or ADR-M than in group ADR at week 34. Urinary protein excretion was significantly lower in group ADR-H than in group ADR in all observation periods and was also lower in group ADR-M than in group ADR at weeks 28 and 32. Both glomerular sclerosis and tubular change were significantly less severe in group ADR-H, while tubular change was less marked in group ADR-M than in group ADR. These results revealed that phosphate depletion was induced, and progressive renal failure was ameliorated in proportion to the dosing of AH. On the other hand, body weight was significantly smaller in group ADR-H than in group ADR in more than half of the observation period. In conclusion, a high dose of AH may adversely affect the nutritional state irrespective of having an extremely protective effect on progress of renal dysfunction. Appropriate doses of AH should be used to prevent the renal deterioration.
Natural bioadhesive biodegradable nanoparticles-based topical ophthalmic formulations for sustained celecoxib release: in vitro study (2013)

Background: Our goal was to prepare and evaluate topical ophthalmic formulations containing optimized celecoxib-loaded bioadhesive cationic chitosan or anionic alginate nanoparticles for sustained release of
Task-driven Modular Co-design of Vehicle Control Systems (2022)

When designing autonomous systems, we need to consider multiple trade-offs at various abstraction levels, and the choices of single (hardware and software) components need to be studied jointly. In this work we consider the problem of designing the control algorithm as well as the platform on which it is executed. In particular, we focus on vehicle control systems, and formalize state-of-the-art control schemes as monotone feasibility relations. We then show how, leveraging a monotone theory of co-design, we can study the embedding of control synthesis problems into the task-driven co-design problem of a robotic platform. The properties of the proposed approach are illustrated by considering urban driving scenarios. We show how, given a particular task, we can efficiently compute Pareto optimal design solutions.
Physical Layer and Multiple Access (2006)

This chapter contains sections titled: Advanced Time Division Multiple Access-ATDMA Code Division Multiple Access Orthogonal Frequency Division Multiplexing Multicarrier CDMA Ultrawide Band Signal MIMO Channels and Space Time Coding References
Spray Drying of Skim Milk Mixed with Milk Permeate: Effect on Drying Behavior, Physicochemical Properties, and Storage Stability of Powder (2008)

The possibility of using milk permeate (MP) to lower the protein level of skim milk powder (SMP) in producing powders of 34% and lower protein is explored. Skim milk suspensions with various levels of MP were prepared by mixing SMP and MP powder (MPP) at the ratios of 1:0, 7:3, 3:7, and 0:1: from 34 to 5.3% protein. The suspensions were dried in a spray dryer with inlet and outlet temperatures of 180 and 80°C, respectively. Increasing permeate concentration in the mixture showed a greater tendency to stickiness manifested by lowered the cyclone recovery of the powder as more powder stuck on the wall of the dryer. Increasing permeate concentration in the resultant powder did not significantly affect the bulk density but led to a reduction in the particle size and also made the powder slight green and yellowish in color. It also found to lower the glass transition temperature (Tg ) of the skim milk powder (SMP) and induce crystallization of lactose at lower water activity (aw ≥ 0.328 for SMP:MPP of 3:7 and 0:1 compared to aw ≥ 0.0.432 for SMP:MPP of 1:0 and 3:7). Addition of MP in SMP lowered the Tg values of the resulting powders. The permeate fraction in spray-dried SMP/MPP mixtures found to lower the critical aw and moisture content, suggesting the SMP mixed with MPP is more likely to become sticky than SMP alone (at 34% protein) when stored at a similar water activity and moisture content.
Effect of Upper Airway Stimulation in Patients with Obstructive Sleep Apnea (EFFECT): A Randomized Controlled Crossover Trial (2021)

In comparison with sham stimulation, therapeutic UAS reduced OSA severity, sleepiness symptoms, and improved quality of life among participants with moderate-to-severe OSA.
NeuralDiff: Segmenting 3D objects that move in egocentric videos (2021)

Given a raw video sequence taken from a freely-moving camera, we study the problem of decomposing the observed 3D scene into a static background and a dynamic foreground containing the objects that move within the scene. This task is reminiscent of the classic background subtraction problem, but is significantly harder because all parts of the scene, static and dynamic, generate a large apparent motion due to the camera large viewpoint change and parallax. In particular, we consider egocentric videos and further separate the dynamic component into objects and the actor that observes and moves them. We achieve this factorization by reconstructing the video via a triple-stream neural rendering network that explains the different motions based on corresponding inductive biases. We demonstrate that our method can successfully separate the different types of motion, outperforming recent neural rendering baselines at this task, and can accurately segment the moving objects. We do so by assessing the method empirically on challenging videos from the EPIC-KITCHENS dataset which we augment with appropriate annotations to create a new benchmark for the task of dynamic object segmentation on unconstrained video sequences, for complex 3D environments.
Conditions for the Validity of the Angular Spectrum of Plane Waves* (1968)

The representation of the electromagnetic field as an angular spectrum of plane waves is becoming increasingly popular in the treatment of certain problems in physical optics. In this paper the equivalence of the angular-spectrum representation and of one of Rayleigh’s integral transforms is demonstrated. Making use of conditions under which the Rayleigh integral formula exists as the unique solution to a certain class of boundary-value problems, conditions under which the angular-spectrum representation is valid are discussed.
Direct Torque and Frequency Control of Double-Inverter-Fed Slip-Ring Induction Motor Drive (2004)

A novel sensorless scheme for direct torque and frequency control of a double-inverter-fed slip-ring induction motor is presented. The analysis of a double-inverter-fed induction motor is given to derive the proposed controller. Various frequency profiles are analyzed for a direct frequency controller. A novel frequency profile is suggested to make the sensorless drive operation reliable and machine parameter independent at any rotor speed. Simulation and experimental results are presented from a 50-hp drive, demonstrating that the drive can deliver full torque from 0 to 2-p.u. speed in either direction. Thus, double the rated power can be extracted from the motor without overloading it.
An Integrated System for Assessing Stroke Risk (2007)

The objective of this article is to present an integrated system for the assessment of risk of stroke based on two modules: 1) clinical risk factors and noninvasive investigations, and 2) carotid plaque texture analysis. The system supports the data collected from the Asymptomatic Carotid Stenosis and Risk of Stroke (ACSRS) natural history study that includes following data: 1) clinical, biochemical, and electrocardiographic risk factors associated with cardiovascular deaths, and 2) whether any independent risk factors can be used to identify a high-risk group for cardiovascular death. Furthermore, the carotid plaque texture analysis module supports the normalization, despeckling, segmentation, texture feature extraction, and classification of ultrasound plaque images.
Development of a Web-Based Genetics Institute for a Nursing Audience (2004)

The purpose of this article is to serve as a resource for readers considering the development of a web-based continuing education offering in their particular specialty areas. A theory-based instructional design using a face-to-face genetics summer institute as a content template and incorporating several levels of planned formative evaluation are described. Summative evaluation strategies revealing satisfaction with the format, improved knowledge, and ability to use genetics knowledge in participants' work setting are also discussed. Finally, lessons learned following completion of two 18-week web-based genetics institutes are shared.
Model-based predictions of solid state intermetallic compound layer growth in hybrid microelectronic circuits (1997)

A mathematical model was developed to quantitatively describe the intermetallic compound (IMC) layer growth that takes place between a Sn-based solder and a noble metal thick film conductor material used in hybrid microcircuit (HMC) assemblies. The model combined the reaction kinetics of the solder/substrate interaction, as determined from ancillary isothermal aging experiments, with a 2-D finite element mesh that took account of the porous morphology of the thick film coating. The effect of the porous morphology on the IMC layer growth when compared to the traditional 1-D computations was significant. The previous 1-D calculations under-predicted the nominal IMC layer thickness relative to the 2-D case. The 2-D model showed greater substrate consumption by IMC growth and lesser solder consumption that was determined with the 1-D computation. The new 2-D model allows the design engineer to better predict circuit aging and hence, the reliability of HMC hardware that is placed in the field.
Serendipitous Diagnosis of Protein S Deficiency (2002)

A 46-year-old male sought periodontal care for a swelling on his right mandibular gingiva. An excisional biopsy revealed a well-differentiated squamous cell carcinoma. Surgical treatment consisted of a right segmental mandibulectomy with ipsilateral right neck dissection and fibular free flap reconstruction. Two days after the surgical procedure, a weakened Doppler signal suggested vascular compromise of the graft. The patient was returned to the operating room where complete thrombosis of the internal jugular vein (recipient vessel) was observed. This event prompted a complete hematological evaluation that disclosed low serum levels of protein S. The patient was started on systemic heparin and local medicinal leeches. A week later, systemic warfarin sodium was added and successfully resolved the vascular compromise of the graft. Two years later, the patient is active and lives a full life with occasional adjustments of warfarin sodium. This case represents the first report on the treatment of gingival carcinoma that led to the serendipitous discovery of an unrelated and unusual systemic condition, protein S deficiency.
The alterations of liver sinusoidal endothelial fenestration in experimental alcoholic fatty liver. (1989)

Lieberらの方法に準じてラットにアルコール性脂肪肝を作成し,肝類洞内皮細胞小孔(SEF)の変化を定量的に解析した.さらに断酒後の変化についてもそのコントロールと比較検討した.正常ラットではzone 1のSEFの直径はzone 3より有意(p<0,001)に大きく,その数はzone 3の方が有意(p<0.001)に多かった.SEFの有孔度はzone 1よりzone 3の方が有意(p<0.01)に大きかった.慢性エタノール投与によりzone 3でSEFの直径は有意(p<0.001)に増大し,数はzone 1よりzone 3で有意(p<0.01)に減少した.SEFの有孔度はzone 1よりzone 3で有意(p<0.001)に増大した.1週間の断酒後,そのコントロールに比しzone 3のSEFの直径で有意差(p<0.05)を認めたが,その数,有孔度には有意差は認めなかった.慢性エタノール時のzone 3のSEFの変化は肝臓のadaptiveな変化と考えられたが,その結果アルコール性脂肪肝の成立に関与することが示唆された.
Intermittent Hypoxia Induces Proteasome-Dependent Down-Regulation of Estrogen Receptor α in Human Breast Carcinoma (2004)

Intermittent hypoxia can cause persistent changes in proteasome function that may contribute to reduced ER-alpha expression in breast tumors and consequently to diminished response and development of resistance to endocrine therapy.
Reconfigurable RO-Path Delay Sensor (2018)

In this brief, we propose a method of analyzing signal propagation delay in certain digital circuits and a delay-sensing architecture. Based on controllability probabilities, we present a graph model that is useful for path delay analysis, derivation of test vectors that sensitize paths of interest, and reconvergent path detection. A delay-sensing architecture is illustrated that offers different accuracy levels and provides a nearly-on-the-fly measurement of the delay. The synergy of the introduced model with the introduced architecture is demonstrated by means of an example. The proposed technique can be used for delay estimation, delay characterization and on-demand, real-time, nearly-on-the-fly estimation of the delay of cell-based array logic units, such as multipliers. FPGA measurements show that a better estimation of the delay is possible, compared to simulations, and an increase by 30% of operation frequency is feasible in certain cases, compared to simulation-based frequency estimation.
The Formation and Behaviour of Montmorillonite During the Use of Wet Forward Combustion in the Alberta Oil Sand Deposits (1979)

ABSTRACT One method of in situ extraction currently being considered for use in the Alberta Oil Sands is Wet Forward Combustion, a process which generates both hydrothermal and high-temperature conditions in the formation. Some of the mineral transformations that may occur under these conditions have been studied in the laboratory with the use of bomb-type autoclaves and a firetube. Montmorillonite was found to form rapidly under hydrothermal conditions from mixtures of kaolinite, quartz and dolomite -- minerals that are frequently present in the Alberta deposits. When metakaolin was substituted for kaolinite, the formation of montmorillonite occurred at a greater rate. Irreversible collapse of montmorillonite did not take place in the fire zone until temperatures as high as 650°C were reached but kaolinite decomposed to metakaolin at 500°C. Under field conditions, the formation of montmorillonite in front of the fire zone can be expected at many localities in the Alberta deposits. Unless unusually high temperatures are reached, irreversible collapse of this mineral is unlikely to occur in the fire zone and its ability to expand and disperse readily in the presence of water will normally be retained. Its continued formation can be expected for some time behind the fire zone, possibly at an increased rate if temperatures in the fire zone were sufficiently high to transform kaolinite to metakaolin. Montmorillonite is a common cause of formation damage and remedial measures may have to be considered during the application of Wet Forward Combustion in the Alberta Oil Sand deposits.
Dissection of the Role of PfEMP1 and ICAM-1 in the Sensing of Plasmodium falciparum-Infected Erythrocytes by Natural Killer Cells (2007)

PfEMP1-independent but ICAM-1/LFA-1-dependent events occurring during NK cell activation by Pf highlight the fundamental role of cellular cooperation during innate immune response to malaria.
Molecular Mechanism of the Airborne Transmissibility of H9N2 Avian Influenza A Viruses in Chickens (2014)

Our study investigates the airborne transmissibility of H9N2 viruses in chickens and the subsequent epidemic. H9N2 virus is the donor for several prevalent reassortant influenza viruses, such as H7N9/2013 and the H5N1 viruses. Poultry as the reservoir hosts of influenza virus is closely associated with human society. Airborne transmission is an efficient pathway for influenza virus transmission among flocks and individuals. Exploring the mechanism of the airborne transmission of the H9N2 virus in chickens could provide essential data regarding prevention and control of influenza endemics and pandemics.
The J-domain protein Rme-8 interacts with Hsc70 to control clathrin-dependent endocytosis in Drosophila (2004)

By screening for mutants exhibiting interactions with a dominant-negative dynamin, we have identified the Drosophila homologue of receptor-mediated endocytosis (Rme) 8, a J-domain-containing protein previously shown to be required for endocytosis in Caenorhabditis elegans. Analysis of Drosophila Rme-8 mutants showed that internalization of Bride of sevenless and the uptake of tracers were blocked. In addition, endosomal organization and the distribution of clathrin were greatly disrupted in Rme-8 cells, suggesting that Rme-8 participates in a clathrin-dependent process. The phenotypes of Rme-8 mutants bear a strong resemblance to those of Hsc70-4, suggesting that these two genes act in a common pathway. Indeed, biochemical and genetic data demonstrated that Rme-8 interacts specifically with Hsc70-4 via its J-domain. Thus, Rme-8 appears to function as an unexpected but critical cochaperone with Hsc70 in endocytosis. Because Hsc70 is known to act in clathrin uncoating along with auxilin, another J-protein, its interaction with Rme-8 indicates that Hsc70 can act with multiple cofactors, possibly explaining its pleiotropic effects on the endocytic pathway.
Nanomechanical Energy Transfer and Resonance Effects in Single-Walled Carbon Nanotubes (2007)

Molecular dynamics simulations are employed to elucidate the important factors in mechanical energy transfer between carbon nanotubes. Our calculations show that sharp resonance effects allow for near complete and highly efficient energy transfer. In addition, the weak coupling between two nanotubes sets the time scale for the energy transfer. The simulations provide the mechanistic basis for a theoretical description of lattice vibration mediated heat flow in nanoscale materials.
k-NN Boosting Prototype Learning for Object Classification (2010)

Object classification is a challenging task in computer vision. Many approaches have been proposed to extract meaningful descriptors from images and classifying them in a supervised learning framework. In this paper, we revisit the classic k-nearest neighbors (k-NN) classification rule, which has shown to be very effective when dealing with local image descriptors. However, k-NN still features some major drawbacks, mainly due to the uniform voting among the nearest prototypes in the feature space. In this paper, we propose a generalization of the classic k-NN rule in a supervised learning (boosting) framework. Namely, we redefine the voting rule as a strong classifier that linearly combines predictions from the k closest prototypes. To induce this classifier, we propose a novel learning algorithm, MLNN (Multiclass Leveraged Nearest Neighbors), which gives a simple procedure for performing prototype selection very efficiently. We tested our method on 12 categories of objects, and observed significant improvement over classic k-NN in terms of classification performances.
Trie-join (2010)

A string similarity join finds similar pairs between two collections of strings. It is an essential operation in many applications, such as data integration and cleaning, and has attracted significant attention recently. In this paper, we study string similarity joins with edit-distance constraints. Existing methods usually employ a filter-and-refine framework and have the following disadvantages: (1) They are inefficient for the data sets with short strings (the average string length is no larger than 30); (2) They involve large indexes; (3) They are expensive to support dynamic update of data sets. To address these problems, we propose a novel framework called trie-join , which can generate results efficiently with small indexes. We use a trie structure to index the strings and utilize the trie structure to efficiently find the similar string pairs based on subtrie pruning. We devise efficient trie-join algorithms and pruning techniques to achieve high performance. Our method can be easily extended to support dynamic update of data sets efficiently. Experimental results show that our algorithms outperform state-of-the-art methods by an order of magnitude on three real data sets with short strings.
The Effects of Alar Base Augmentation in Secondary Unilateral Cleft Lip Nasal Deformity (2020)

In unilateral cleft lip and palate patients, the alar base is displaced inferoposterolaterally due to the depression of the pyriform aperture in the cleft side, and the drooping of the nostril rim is provoked by displacement of the alar base. This study was conducted between May 1998 and December 2012. In total, 82 patients with secondary unilateral cleft lip nasal deformities were treated using alar base augmentation. The patients were divided into two groups according to the degree of their preoperative alar base asymmetry. Patients with alar base asymmetry <3 mm were treated with a soft tissue augmentation procedure. Those with alar base asymmetry >3 and <6 mm were treated with a bony augmentation procedure. Soft tissue augmentation was conducted in 42 patients, and bony augmentation was conducted in 40 patients. In the soft tissue augmentation group, the degree of alar base asymmetry was improved from 2.42 ± 0.38 mm preoperatively to 0.45 ± 0.21 mm postoperatively (P < 0.05). In the bony augmentation group, the degree of alar base asymmetry was improved from 4.33 ± 0.50 mm preoperatively to 0.81 ± 0.20 mm postoperatively (P < 0.05). In the amount of alar base augmentation, there were statistically significant differences between the soft tissue augmentation group and the bony augmentation group (P < 0.05). This clinical study shows that secondary cleft lip nasal deformities can be corrected with alar base augmentation using soft tissue and bony augmentation and that these procedures can provide reliable, satisfactory, and safe clinical outcomes.
The Degradation of Silver Trifluoroacetate to Trifluoroiodomethane (1950)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Degradation of Silver Trifluoroacetate to TrifluoroiodomethaneAlbert L. Henne and William G. FinneganCite this: J. Am. Chem. Soc. 1950, 72, 8, 3806–3807Publication Date (Print):August 1, 1950Publication History Published online1 May 2002Published inissue 1 August 1950https://pubs.acs.org/doi/10.1021/ja01164a511https://doi.org/10.1021/ja01164a511research-articleACS PublicationsRequest reuse permissionsArticle Views478Altmetric-Citations30LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts