gebhart/patrepeval huggingface dataset:
Complications of Postmastectomy Breast Reconstruction in Smokers, Ex-smokers, and Nonsmokers (2001)

Padubidri, Arvind N. M.D.; Yetman, Randall M.D.; Browne, Earl M.D.; Lucas, Armand M.D.; Papay, Frank M.D.; Larive, Brett M.S.; Zins, James M.D.; Vasconez, Luis O. M.D. Author Information
A Deep Reinforcement Learning Approach for VNF Forwarding Graph Embedding (2019)

Network Function Virtualization (NFV) and service orchestration simplify the deployment and management of network and telecommunication services. The deployment of these services requires, typically, the allocation of Virtual Network Function - Forwarding Graph (VNF-FG), which implies not only the fulfillment of the service's requirements in terms of Quality of Service (QoS), but also considering the constraints of the underlying infrastructure. This topic has been well-studied in existing literature, however, its complexity and uncertainty of available information unveil challenges for researchers and engineers. In this paper, we explore the potential of reinforcement learning techniques for the placement of VNF-FGs. However, it turns out that even the most well-known learning technique is ineffective in the context of a large-scale action space. In this respect, we propose approaches to find out feasible solutions while improving significantly the exploration of the action space. The simulation results clearly show the effectiveness of the proposed learning approach for this category of problems. Moreover, thanks to the deep learning process, the performance of the proposed approach is improved over time.
Plane-wave illumination of concentric-ring frequency-selective surfaces (1985)

In the paper we present the results of a modal analysis of the current distribution around the circumference of thin concentric rings arranged on both square and equilateral triangular lattices. The particular case of plane-wave illumination at 45Â° incidence is considered owing to its relevance to oblique-incidence diplexer systems. Measured and predicted transmission curves, together with computer curves illustrating the frequency dependence of various current-mode amplitudes, are plotted for selected concentric-ring structures, each with the same mean radius for the outer ring, but with different inner-ring radii. The results relate individual current modes to features in the observed transmission curves. They confirm that the copolar transmission and lower reflection bands can be modelled with only one current mode in each ring. Crosspolar effects are discussed for incidence on the square lattice in the planes Â¿ = 0, 45Â° and 90Â°, where they are shown to be small for pure TE and TM.
The use of β-cyclodextrins to enhance the aqueous solubility of trichloroethylene and perchloroethylene and their removal from soil organic matter: Effect of substituents (2003)

This paper describes a systematic study for the evaluation of different substituted β-cyclodextrins (β-CDs), as agents for the enhancement of the aqueous solubility of two major organic pollutants, trichloroethylene (TCE) and perchloroethylene (PCE). The aqueous solubility enhancement occurs through the formation of hostguest inclusion complexes between the CD molecule (host) and the polychloroethylene (guest) and is driven primarily by hydrophobic forces. The CDs evaluated are: methyl-β-CD (Mβ-CD), hydroxypropyl-β-CD (HPβ-CD), carboxymethyl-β-CD (CMβ-CD1, CMβ-CD2), and sulfated-β-CD (Sβ-CD1, Sβ-CD2); the degree of substitution was also varied. Using a 5% (w/v) aqueous CD solution, solubility enhancement factors (S t /S o ) up to 5.5 and 14 were determined for TCE and PCE, respectively. Binding constants (K 11 ) for TCE with the substituted CDs were evaluated using an 1 H NMR technique; these were found to range from 3 to 120 M 1 . It was shown that solubility enhancement, as well as the binding constant, is dependent on the type and degree of substitution of the β-CD molecule; the determining factors are discussed. The CDs are also capable of effective removal of PCE and TCE retained by soil organic matter. Thus, a suitably substituted β-CD may be a valuable additive in pump-and-treat protocols for site remediation of polychlorinated organics. Key words: Cyclodextrin, trichloroethylene, perchloroethylene, solubility enhancement, binding constant, soil and water remediation.
Polymerase‐Functionalized Hierarchical Mesoporous Titania Thin Films: Towards a Nanoreactor Platform for DNA Amplification (2010)

Titania thin films with hierarchical nanopore architecture are efficient hosts for Taq polymerase, which is selectively located in large-size mesopores. These biofunctional nanomaterials, highly tuned on the biomolecular length scale, are able to efficiently amplify DNA in a polymerase chain reaction. The engineered pore sizes and interconnectivity at the nanoscale are the key to bio-functionalization and enzyme performance.
Natural Frequencies of Magnetoelastic Longitudinal Wave Propagation in an Orthotropic Circular Cylinder (2012)

In this paper, we study the longitudinal wave propagation in a perfectly conducting elastic circular cylinder in the presence of an axial initial magnetic field. The elastic cylinder is assumed to be made of an orthotropic material. The problem is represented by the equations of elasticity taking into account of the effect of the magnetic field as given by Maxwell&amp;apos;s equations in the quasi-static approximation. The stress free conditions on the inner and outer surfaces of the hollow circular cylinder are used to form a frequency equation in terms of the wavelength, the cylinder radii and the material constants. Numerical calculations are obtained and the results are represented graphically. It is observed that the longitudinal elastic waves in a solid body propagating under the influence of a superimposed magnetic field can be different significantly from that of those propagating in the absence of a magnetic field. Also, elastic waves may convey information on electromagnetic properties of the material: for example through a precise measurement of the surface current induced by the presence of the magnetic field. Finally, some of the earlier results are deduced as particular cases.
Ca-SiAlON Glasses: Effects of Fluorine on Glass Formation and Properties (2007)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
Direct sample polymerase chain reaction for the detection of Mycoplasma pneumoniae: a simple system for clinical application. (1995)

A semi-nested polymerase chain reaction system with primers derived from the P1 adhesin gene of Mycoplasma pneumoniae was evaluated for sensitivity and specificity for detection of M. pneumoniae. The method used target DNA within samples of M. pneumoniae broth cultures and clinical material, without a formal extraction process. The sensitivity for detection of DNA was found to be to a level of one copy per sample and was specific to M. pneumoniae only, discriminating from the other human mycoplasma and ureaplasma species tested. The system offers the opportunity for a simple and highly specific laboratory method for diagnosis which may be compared to currently available serological methods, and may provide another method of studying mycoplasma-induced pathology.
Regulation of human B cell activation by prostaglandin E2. Suppression of the generation of immunoglobulin-secreting cells. (1985)

The role of prostaglandin E2 (PGE2) in the generation of immunoglobulin-secreting cells (ISC) from human peripheral blood B cells was examined. Initial studies demonstrated that monocyte (M phi)-mediated suppression of the generation of ISC in Staphylococcus aureus (SA)-stimulated cultures was mitigated by indomethacin, and thus suggested that the cyclooxygenase pathway products of arachidonic acid played a role in the regulation of B cell activation. The possibility that PGE2, one of the major products of this pathway generated by M phi-affected human B cell responses, was therefore investigated. PGE2 was found to cause concentration-dependent inhibition of the generation of ISC in pokeweed mitogen- or SA-stimulated B cell cultures supported by T cells. Studies were therefore carried out to determine whether PGE2 inhibited the production of necessary T cell factors or directly altered B cell responsiveness. Initially, the effect of PGE2 on the capacity of mitogen-stimulated cells to secrete a factor that supported the differentiation of B cells into ISC was investigated. Excessive numbers of M phi or PGE2 inhibited the production of B cell differentiation factor from mitogen-stimulated T cells. The effect of PGE2 on the capacity of B cells to differentiate into ISC was more complex. PGE2 inhibited the generation of ISC when B cells were stimulated with SA and B cell differentiation factor-containing T cell supernatants. PGE2-mediated inhibition of ISC generation was observed even when addition of PGE2 was delayed until after ISC first were detected in culture. By contrast, PGE2 caused only minimal inhibition of the generation of ISC cultures stimulated by T cell supernatants alone or protein A-free SA and T cell supernatants. These results suggested that SA-responsive B cells were particularly sensitive to inhibition by PGE2. Additional experiments supported the conclusion that B cell sensitivity to inhibition by PGE2 is augmented by the immunoglobulin cross-linking effects of protein A-containing SA. Overall, the results support the conclusion that PGE2 at physiologically relevant concentrations can influence human antibody responses by means of a direct inhibitory action on the responding B cell or an indirect one on the production of necessary T cell factors.
La dénitrification dans les réacteurs de méthanisation. Interactions entre les microorganismes impliqués et conséquences sur la conduite des procédés (1997)

* INRA Laboratoire de Biotechnologie de l'Environnement, Avenue des Etangs, 11100 Narbonne Diffusion du document : INRA Laboratoire de Biotechnologie de l'Environnement, Avenue des Etangs, 11100 Narbonne
Density and temperature of N atoms in the afterglow of a microwave discharge measured by a two-photon laser-induced fluorescence technique (2001)

Both the axial density and temperature profiles of ground-state nitrogen atoms have been measured in a microwave discharge and its afterglow in the presence of the so-called short-lived afterglow by means of two-photon absorption laser-induced fluorescence (TALIF). The temperature is obtained from the Doppler broadening of the spectral profile, after deconvolution with the laser profile. The N atom temperature decreases from about 1400 K in the end of the discharge zone to about 300 K in the downstream part of the afterglow. The sharp temperature decrease immediately behind the discharge zone can reasonably be explained by heat transfer to the flow tube wall. The absolute N atom density is obtained by calibrating the fluorescence yield with a TALIF signal from krypton atoms. The N density increases from 1.5*10/sup 21/ m/sup -3/ in the discharge zone to about 3.5*10/sup 21/ m/sup -3/ in the late afterglow. However, the N atom flux is conserved along the flow tube, indicating negligible consumption or production of N atoms in the short-lived afterglow
Upgrading Pyrolysis Oil over Ni/HZSM‐5 by Cascade Reactions (2012)

Bio-basierte Kohlenwasserstoffe: Mit einem aktiven, selektiven und stabilen Katalysator (Ni auf dem Zeolith HZSM-5 als Träger) lassen sich – in einer Kaskade aus Hydrierungen, Hydrolysen, Dehydrierungen und Dehydroaromatisierungen – verschiedenste C-O- und CO-Bindungen in mit n-Hexan extrahiertem Pyrolyseöl in Kohlenwasserstoffe überführen. Unter milden Bedingungen wurden so in Wasser die Benzinkohlenwasserstoffe C5–C9 erhalten.
Comparison of Intensity- and Polarization-based Contrast in Amyloid-beta Plaques as Observed by Optical Coherence Tomography (2019)

One key hallmark of Alzheimer’s disease (AD) is the accumulation of extracellular amyloid-beta protein in cortical regions of the brain. For a definitive diagnosis of AD, post-mortem histological analysis, including sectioning and staining of different brain regions, is required. Here, we present optical coherence tomography (OCT) as a tissue-preserving imaging modality for the visualization of amyloid-beta plaques and compare their contrast in intensity- and polarization-sensitive (PS) OCT. Human brain samples of eleven patients diagnosed with AD were imaged. Three-dimensional PS-OCT datasets were acquired and plaques were manually segmented in 500 intensity and retardation cross-sections per patient using the freely available ITK-SNAP software. The image contrast of plaques was quantified. Histological staining of tissue sections from the same specimens was performed to compare OCT findings against the gold standard. Furthermore, the distribution of plaques was evaluated for intensity-based OCT, PS-OCT and the corresponding histological amyloid-beta staining. Only 5% of plaques were visible in both intensity and retardation segmentations, suggesting that different types of plaques may be visualized by the two OCT contrast channels. Our results indicate that multicontrast OCT imaging might be a promising approach for a tissue-preserving visualization of amyloid-beta plaques in AD.
Physical and chemical characterization of ultra low-k SiCOH films by X-ray reflectometry and GISAXS (2013)

Advanced low-k (ALK) porous SiCOH films have been deposited onto a silicon substrate by plasma enhancement chemical vapor deposition (PECVD). Some of these samples were submitted to plasmas in order to investigate its effects on the pore sealing and hydrophobicity. The films were characterized by X-ray based method and ellipsometry spectroscopy. The results indicate that plasma treatment leads to the formation of a thin dense layer onto the surface of the ALK films and yields the reduction of the total thickness as consequence of the pore sealing effect. The density of the thin layer as well as the magnitude of the contraction depends on the plasma type. The grazing incidence small angle X-ray scattering interpreted by means of the Kratky method, shows that both pore size and porosity are also reduced by the plasma treatment. Kratky analysis shows that the porous matrix can be modeled as the coexistence of three types of pores with spherical and cylindrical features.
Investigations on the Mechanical Properties of Glass Fiber/Sisal Fiber/Chitosan Reinforced Hybrid Polymer Sandwich Composite Scaffolds for Bone Fracture Fixation Applications (2020)

This study aims to explore the mechanical properties of hybrid glass fiber (GF)/sisal fiber (SF)/chitosan (CTS) composite material for orthopedic long bone plate applications. The GF/SF/CTS hybrid composite possesses a unique sandwich structure and comprises GF/CTS/epoxy as the external layers and SF/CTS/epoxy as the inner layers. The composite plate resembles the human bone structure (spongy internal cancellous matrix and rigid external cortical). The mechanical properties of the prepared hybrid sandwich composites samples were evaluated using tensile, flexural, micro hardness, and compression tests. The scanning electron microscopic (SEM) images were studied to analyze the failure mechanism of these composite samples. Besides, contact angle (CA) and water absorption tests were conducted using the sessile drop method to examine the wettability properties of the SF/CTS/epoxy and GF/SF/CTS/epoxy composites. Additionally, the porosity of the GF/SF/CTS composite scaffold samples were determined by using the ethanol infiltration method. The mechanical test results show that the GF/SF/CTS hybrid composites exhibit the bending strength of 343 MPa, ultimate tensile strength of 146 MPa, and compressive strength of 380 MPa with higher Young's modulus in the bending tests (21.56 GPa) compared to the tensile (6646 MPa) and compressive modulus (2046 MPa). Wettability study results reveal that the GF/SF/CTS composite scaffolds were hydrophobic (CA = 92.41° ± 1.71°) with less water absorption of 3.436% compared to the SF/CTS composites (6.953%). The SF/CTS composites show a hydrophilic character (CA = 54.28° ± 3.06°). The experimental tests prove that the GF/SF/CTS hybrid composite can be used for orthopedic bone fracture plate applications in future.
Cloning of the Tannerella forsythensis (Bacteroides forsythus) siaHI gene and purification of the sialidase enzyme (2003)

Tannerella forsythensis (previously named Bacteroides forsythus) is a Gram-negative, anaerobic, fusiform bacterium that is a primary or secondary aetiological agent in periodontal disease in humans. T. forsythensis expresses several putative virulence factors, including a sialidase; however, there has been no molecular genetic characterization of this enzyme. A sialidase clone (pHI-1) was screened from a total of 455 recombinant clones of a genomic DNA library using the 2'- (4-methylumbelliferyl)-alpha-D-N-acetylneuraminic acid (MUNeuAc) filter-paper spot assay. The sialidase gene ORF (siaHI) consists of a 1395 bp coding sequence and encodes a protein with 465 amino acids with an overall molecular mass of 52 kDa. The sialidase does not have sequence similarity to any other bacterial sialidase. The entire sialidase ORF was expressed in Escherichia coli. Furthermore, the sialidase was purified from the type strain of T. forsythensis and from a recombinant clone, pHI-1 : 1, and was analysed using a non-denaturing gel, revealing that the enzyme preparations were respectively separated as two major bands and as a single band. Southern blot hybridization analysis revealed similar patterns of siaHI-hybridizing bands among clinical isolates of T. forsythensis from periodontitis patients. This is the first study on the cloning and expression of a T. forsythensis sialidase gene and the purification of the SiaHI enzyme from T. forsythensis ATCC 43037(T) and recombinant E. coli.
Loop Diuretic Efficiency (2013)

Although in need of validation in less-selected populations, low DE during decongestive therapy portends poorer long-term outcomes above and beyond traditional prognostic factors in patients hospitalized with decompensated heart failure.
Flow Cytometric Analysis of Micronuclei in Peripheral Blood Reticulocytes III. An Efficient Method of Monitoring Chromosomal Damage in the Beagle Dog (2007)

Erythrocyte-based micronucleus tests have traditionally analyzed bone marrow because splenic filtration in most species removes micronucleated cells from peripheral blood. We have evaluated a flow cytometric method for monitoring micronucleated reticulocyte frequencies (%MN-RET) in the peripheral blood of beagle dogs treated with cyclophosphamide (CP) and have found that analysis of micronucleated reticulocytes (MN-RETs) in peripheral blood is a suitable surrogate for bone marrow analysis. The three-color flow cytometric method uses anti-CD71 labeling to identify reticulocytes and Plasmodium berghei-containing erythrocytes as a calibration standard. The spontaneous %MN-RET determined by flow cytometry was 0.31 +/- 0.09% (n = 22) for peripheral blood, compared with 0.38 +/- 0.13% (SD, n = 12) for bone marrow, and 0.27 +/- 0.08% (n = 12) for peripheral blood by microscopic scoring with acridine orange staining. The kinetics of appearance and disappearance of MN-RETs in blood were determined by collecting daily samples after iv treatment with CP. The maximum frequency occurred approximately 48 h after dosing. Frequencies of MN-RETs in peripheral blood at steady state following daily CP treatment were 55-68% of corresponding bone marrow values assessed by microscopy and 55-112% as assessed by flow cytometry. This difference is presumably due to splenic removal, which appears slightly less stringent than that previously reported for CP-treated Sprague-Dawley rats. Responses in bone marrow and peripheral blood were highly correlated and similar to or greater than those reported in mice and rats at equitoxic doses.
One-Minute Deep Breathing Assessment and its Relationship to 24-h Heart Rate Variability Measurements (2018)

Background: Heart rate variability (HRV), the change in the time intervals between successive pairs of heartbeats, is influenced by interdependent regulatory systems operating over different time scales to adapt to psychological challenges and environmental demands. Low ageadjusted HRV is predictive of upcoming health challenges in healthy people as well as a wide range of diseases in patients and correlates with allcause mortality. 24h HRV recordings are considered the “gold standard” and have greater predictive power on health risk than shortterm recordings. However, it is not typically costeffective or practical to acquire 24h HRV recordings. This has led to the growing use of shortterm recordings in research and clinical assessments. Objective: The first study examined the correlations between a 10min restingstate period, a 1min paced deep breathing protocol, response to handgrip, and 24h HRV measures in 28 healthy individuals. Based on the results of the initial study, the primary study examined the correlations between the 1min paced deep breathing assessment and 24h measures in a general population of 805 individuals. Results: The highest correlations for the HRV variables were with the vagally mediated sources of HRV. The 1min paced deep breathing was positively correlated with 24h highfrequency power ( r = 0.60, P &lt; 0.01), root mean square of successive difference ( r = 0.62, P &lt; 0.01), lowfrequency (LF) power ( r = 0.64, P &lt; 0.01), veryLF power ( r = 0.57, P &lt; 0.01) total power ( r = 0.42, P &lt; 0.01), standard deviation of normaltonormal interval (SDNN) index ( r = 0.59, P &lt; 0.01), and SDNN ( r = 0.41, P &lt; 0.01). Conclusions: The findings from this study suggest that the 1min paced deep breathing protocol is an ideal shortterm assessment that can be used in a health risk screening context. When low values are observed, it is recommended that a 24h assessment be conducted.