gebhart/patrepeval huggingface dataset:
Comparing fixed and variable segment durations for adaptive video streaming (2020)

HTTP Adaptive Streaming (HAS) is the de-facto standard for video delivery over the Internet. It enables dynamic adaptation of video quality by splitting a video into small segments and providing multiple quality levels per segment. So far, HAS services typically utilize a fixed segment duration. This reduces the encoding and streaming variability and thus allows a faster encoding of the video content and a reduced prediction complexity for adaptive bit rate algorithms. Due to the content-agnostic placement of I-frames at the beginning of each segment, additional encoding overhead is introduced. In order to mitigate this overhead, variable segment durations, which take encoder placed I-frames into account, have been proposed recently. Hence, a lower number of I-frames is needed, thus achieving a lower video bitrate without quality degradation. While several proposals exploiting variable segment durations exist, no comparative study highlighting the impact of this technique on coding efficiency and adaptive streaming performance has been conducted yet. This paper conducts such a holistic comparison within the adaptive video streaming eco-system. Firstly, it provides a broad investigation of video encoding efficiency for variable segment durations. Secondly, a measurement study evaluates the impact of segment duration variability on the performance of HAS using three adaptation heuristics and the dash.js reference implementation. Our results show that variable segment durations increased the Quality of Experience for 54% of the evaluated streaming sessions, while reducing the overall bitrate by 7% on average.
Effect of Dislocation Density in an Unrecrystallized Part of Austenite on Growth Rate of Recrystallizing Grain (1994)

The growth rate of recrystallizing austenite grains of Si-Mn steels and Nb added steels after hot deformation was investigated by measurement of the fraction of recrystallized austenite and recrystallized austenite grain size. The fraction of recrystallized austenite(Xcr) at which the mechanism of recrystallization changed from nucleation and growth (NG) to site saturation (SS) was formulated as a function of Nb concentration and deformation conditions.According to the increase in deformation temperature and strain, Xcr increases while the increase in Nb in solution decreases Xcr.The growth rate of recrystallizing austenite was also formulated as a function of strain energy (Fv) and Nb concentration. Strain energy, Fv is calculated with the dislocation density decreasing due to static recovery during holding time after deformation by the method shown in the previous reports. The growth rate decreases rapidly after deformation due to the decrease in Fv and is obviously restrained by Nb addition.
It takes partnerships to support long-term housing solutions (2016)

Women's Property Initiatives (WPI) provides affordable, long-term homes for over 180 women and children around Melbourne. Like most community housing providers, we have a tenancy management model with additional support being provided by other community services. We work in partnership with many support agencies such as mental health, disability and family services to help our tenants live with dignity and contribute to their communities. These partnerships enable the women we house to achieve the long-term tenancies necessary to build a secure future.
O1–07–04: Rapid and progressive neurofibrillary tangle pathology in a novel in vivo model of tau propagation: Pattern of spread is determined by structural connectivity not spatial proximity (2013)

Aberrant intracellular inclusions composed of hyperphosphorylated filamentous tau are a neuropathological hallmark of Alzheimer's disease, progressive supranuclear palsy and other sporadic neurodegenerative disorders, which have been collectively termed tauopathies. The discovery that pathogenic mutations in the tau gene (MAPT) can cause a familial neurodegenerative tauopathy has provided compelling evidence that tau dysfunction is sufficient to cause neurodegeneration. Therefore inhibiting potentially toxic events such as tau inclusion formation are attractive targets for therapeutic intervention and disease prevention. A string of recent in vitro and in vivo studies have shown that tau aggregates have 'prion-like' properties which not only allow them to transmit/seed further tau aggregation, but also spread to neighbouring cells or connected brain regions. This process is referred to as 'tau propagation' and might explain the stereotypic progression of tau pathology in Alzheimer's disease and other tauopathies. In this study, we report a novel in vivo model of tau propagation using young asymptomatic P301S transgenic mice that underwent unilateral hippocampal infusions containing brain extracts from older clinically impaired P301S mice, known to have florid tau aggregates. Detailed neuropathological examination was conducted in these mice (and controls) at various time-points post-infusion to investigate the presence and distribution of tau pathology. Infusion-related tau pathology was induced rapidly (within 2 weeks) in the hippocampus of this model. Tau-positive neurofibrillary tangles increased in a stereotypic and progressive fashion, with robust Gallyas-positive tangles being observed 1 month post-infusion. Contralateral and anterior/posterior spread of tau pathology was also evident and appeared to be dependent on synaptic connectivity rather than spatial proximity. Tau biochemistry confirmed the induction and spread of tau pathology in this model. Previously reported models of tau propagation take several months to develop significant tau pathology attributable to propagation, therefore the rapid and robust propagation phenotype in our model will be instrumental to both basic research and the drug discovery process, with the ultimate aim to find intervention and prevention strategies for human tauopathies.
Recent Trends in Assessment of Cellulose Derivatives in Designing Novel and Nanoparticulate-Based Drug Delivery Systems for Improvement of Oral Health (2021)

Natural polymers are revolutionizing current pharmaceutical dosage forms design as excipient and gained huge importance because of significant influence in formulation development and drug delivery. Oral health refers to the health of the teeth, gums, and the entire oral-facial system that allows us to smile, speak, and chew. Since years, biopolymers stand out due to their biocompatibility, biodegradability, low toxicity, and stability. Polysaccharides such as cellulose and their derivatives possess properties like novel mechanical robustness and hydrophilicity that can be easily fabricated into controlled-release dosage forms. Cellulose attracts the dosage design attention because of constant drug release rate from the precursor nanoparticles. This review discusses the origin, extraction, preparation of cellulose derivatives and their use in formulation development of nanoparticles having multidisciplinary applications as pharmaceutical excipient and in drug delivery, as bacterial and plant cellulose have great potential for application in the biomedical area, including dentistry, protein and peptide delivery, colorectal cancer treatment, and in 3D printable dosage forms.
Synchrotron X-ray Powder Diffraction and Computational Investigation of Purely Siliceous Zeolite Y under Pressure (2004)

High-pressure synchrotron X-ray powder diffraction measurements of a sample of purely siliceous zeolite Y (faujasite) were carried out up to 8.0 GPa at room temperature using a diamond anvil cell. Measurements using silicone oil as the pressure-transmitting medium show compression of the zeolite followed by a loss of long-range ordering at 2.2 GPa. The experimentally determined bulk modulus, 38(2) GPa, is, within experimental error, identical to that of quartz. When using a methanol:ethanol:water mixture (16:3:1) as the pressure-transmitting medium, two distinct compressibility regions are observed with a dramatic change in the compression mechanism at 4 GPa. Rietveld refinement analysis of the powder patterns provides a detailed description of the underlying chemistry, with sequential pore filling the main response up to 4 GPa and framework distortions at higher pressures.
Novel Sorbents for Mercury Removal from Flue Gas (2000)

A laboratory-scale packed-bed reactor system is used to screen sorbents for their capability to remove elemental mercury from various carrier gases. When the carrier gas is argon, an on-line atomic fluorescence spectrophotometer (AFS), used in a continuous mode, monitors the elemental mercury concentration in the inlet and outlet streams of the packed-bed reactor. The mercury concentration in the reactor inlet gas and the reactor temperature are held constant during a test. For more complex carrier gases, the capacity is determined off-line by analyzing the spent sorbent with either a cold vapor atomic absorption spectrophotometer (CVAAS) or an inductively coupled argon plasma atomic emission spectrophotometer (ICP-AES). The capacities and breakthrough times of several commercially available activated carbons as well as novel sorbents were determined as a function of various parameters. The mechanisms of mercury removal by the sorbents are suggested by combining the results of the packed-bed testing with various analytical results.
Highly ordered ZnMnO3 nanotube arrays from a “self-sacrificial” ZnO template as high-performance electrodes for lithium ion batteries (2016)

Highly ordered ZnMnO<sub>3</sub> nanotube arrays show high cycling performance and rate capability when used as an anode material for lithium-ion batteries.
Structures of norbornane and dodecahedrane by molecular mechanics calculations (MM3), x-ray crystallography, and electron diffraction (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructures of norbornane and dodecahedrane by molecular mechanics calculations (MM3), x-ray crystallography, and electron diffractionN. L. Allinger, H. J. Geise, W. Pyckhout, L. A. Paquette, and J. C. GallucciCite this: J. Am. Chem. Soc. 1989, 111, 3, 1106–1114Publication Date (Print):February 1, 1989Publication History Published online1 May 2002Published inissue 1 February 1989https://pubs.acs.org/doi/10.1021/ja00185a048https://doi.org/10.1021/ja00185a048research-articleACS PublicationsRequest reuse permissionsArticle Views240Altmetric-Citations72LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
New developments in CIP practices (1985)

Description des cinq etapes de cette methode de nettoyage sur place (clean-in-place) des appareils et des tuyauteries
Characterization of sulfate-reducing bacteria dominated surface communities during start-up of a down-flow fluidized bed reactor (2008)

An anaerobic down-flow fluidized bed reactor was inoculated with granular sludge and started-up with sulfate containing synthetic wastewater to promote the formation of a biofilm enriched in sulfate-reducing bacteria (SRB), to produce biogenic sulfide. The start-up was done in two stages operating the reactor in batch for 45 days followed by 85 days of continuous operation. Low-density polyethylene was used as support. The biofilm formation was followed up by biochemical and electron microscopy analyses and the composition of the community was examined by 16S rDNA sequence analysis. Maximum immobilized volatile solids (1.2 g IVS/L(support)) were obtained after 14 days in batch regime. During the 85 days of continuous operation, the reactor removed up to 80% of chemical oxygen demand (COD), up to 28% of the supplied sulfate and acetate was present in the effluent. Sulfate-reducing activity determined in the biofilm with ethanol or lactate as substrate was 11.7 and 15.3 g COD/g IVS per day, respectively. These results suggested the immobilization of sulfate reducers that incompletely oxidize the substrate to acetate; the phylogenetic analysis of the cloned 16S rDNA gene sequences showed high identity to the genus Desulfovibrio that oxidizes the substrates incompletely. In contrast, in the granular sludge used as inoculum a considerable number of clones showed homology to Methanobacterium and just few clones were close to SRB. The starting-up approach allowed the enrichment of SRB within the diverse community developed over the polyethylene support.
Estimating synchronization signal phase (2015)

To read a watermark from printed images requires that the watermarking system read correctly after affine distortions. One way to recover from affine distortions is to add a synchronization signal in the Fourier frequency domain and use this synchronization signal to estimate the applied affine distortion. Using the Fourier Magnitudes one can estimate the linear portion of the affine distortion. To estimate the translation one must first estimate the phase of the synchronization signal and then use phase correlation to estimate the translation. In this paper we provide a new method to measure the phase of the synchronization signal using only the data from the complex Fourier domain. This data is used to compute the linear portion, so it is quite convenient to estimate the phase without further data manipulation. The phase estimation proposed in this paper is computationally simple and provides a significant computational advantage over previous methods while maintaining similar accuracy. In addition, the phase estimation formula gives a general way to interpolate images in the complex frequency domain.
Network virtualization in multi-tenant datacenters (2014)

Multi-tenant datacenters represent an extremely challenging networking environment. Tenants want the ability to migrate unmodified workloads from their enterprise networks to service provider datacenters, retaining the same networking configurations of their home network. The service providers must meet these needs without operator intervention while preserving their own operational flexibility and efficiency. Traditional networking approaches have failed to meet these tenant and provider requirements. Responding to this need, we present the design and implementation of a network virtualization solution for multi-tenant datacenters.
Gas-Chromatographic Behavior of Pretreated Silica Gels (1967)

Abstract Silica gels were prepared by acid precipitation and dehydrated by refluxing in the presence of various aromatic solvents. The pretreatment was found to change the surface area and packing density of the gels. The chromatographic behavior of these gels toward organic adsorbates showed the treated gels to give better separations and resolution under time-normalized conditions. The columns were found to be thermally stable up to 200°C for long periods of time.
Recombinant human bone morphogenetic protein‐7 enhances fracture healing in an ischemic environment (2009)

Ischemia predisposes orthopedic trauma patients to delayed fracture healing or nonunion. The goal of this study was to test the ability of bone morphogenetic protein 7 (BMP7) to stimulate fracture repair in an ischemic environment. Ischemic fractures were generated in male adult mice by resecting the femoral artery prior to the creation of a nonstabilized tibia fracture. Recombinant human BMP7 (rhBMP7, 50 microg) was injected into the fracture site immediately after surgery. At 7 days after injury, more tissue vascularization was observed in rhBMP7 treated fractures. Histomorphometric analyses revealed that rhBMP7 induced more cartilage at day 7, more callus and bone at days 14 and 28, and more adipose tissue and fibrous tissue at days 7, 14, and 28 compared to controls (n=5/group/time). At day 28, all fractures treated with rhBMP7 (50 microg, n=5) healed, whereas only three of five control fractures exhibited slight bony bridging. In addition, we found that rhBMP7 (both 10 and 50 microg) significantly increased the amount of cartilage compared to controls in stabilized fractures, confirming its chondrogenic effect. Lastly, using bone marrow transplantation, we determined that no donor-derived osteocytes or chondrocytes were present in rhBMP7-treated fractures, suggesting rhBMP7 did not recruit mesenchymal stem cells from the bone marrow to the fracture site. In conclusion, our results indicate that rhBMP7 is a promising treatment for fractures with severely disrupted blood supply.
Zeb1 facilitates corneal epithelial wound healing by maintaining corneal epithelial cell viability and mobility (2023)

The cornea is the outmost ocular tissue and plays an important role in protecting the eye from environmental insults. Corneal epithelial wounding provokes pain and fear and contributes to the most ocular trauma emergency assessments worldwide. ZEB1 is an essential transcription factor in development; but its roles in adult tissues are not clear. We identify Zeb1 is an intrinsic factor that facilitates corneal epithelial wound healing. In this study, we demonstrate that monoallelic deletion of Zeb1 significantly expedites corneal cell death and inhibits corneal epithelial EMT-related cell migration upon an epithelial debridement. We provide evidence that Zeb1-regulation of corneal epithelial wound healing is through the repression of genes required for Tnfa-induced epithelial cell death and the induction of genes beneficial for epithelial cell migration. We suggest utilizing TNF-α antagonists would reduce TNF/TNFR1-induced cell death in the corneal epithelium and inflammation in the corneal stroma to help corneal wound healing.
One-pot Synthesis of Metal–Organic Frameworks with Encapsulated Target Molecules and Their Applications for Controlled Drug Delivery (2015)

Many medical and chemical applications require target molecules to be delivered in a controlled manner at precise locations. Metal-organic frameworks (MOFs) have high porosity, large surface area, and tunable functionality and are promising carriers for such purposes. Current approaches for incorporating target molecules are based on multistep postfunctionalization. Here, we report a novel approach that combines MOF synthesis and molecule encapsulation in a one-pot process. We demonstrate that large drug and dye molecules can be encapsulated in zeolitic imidazolate framework (ZIF) crystals. The molecules are homogeneously distributed within the crystals, and their loadings can be tuned. We show that ZIF-8 crystals loaded with the anticancer drug doxorubicin (DOX) are efficient drug delivery vehicles in cancer therapy using pH-responsive release. Their efficacy on breast cancer cell lines is higher than that of free DOX. Our one-pot process opens new possibilities to construct multifunctional delivery systems for a wide range of applications.
Hepatitis E virus infection in two different regions of Indonesia with identification of swine HEV genotype 3 (2013)

Hepatitis E is an emerging disease with a high incidence globally. Few data are available on hepatitis E virus (HEV) infection in Indonesia. To obtain molecular information on HEV infection in two regions of Indonesia with different customs and swine breeding conditions, serum samples from 137 swine farm workers, 100 blood donors and 100 swine (27 fecal samples also obtained) in Yogyakarta (Central Java) and from 12 and 64 swine farm workers, 42 and 135 local residents and 89 and 119 swine in Tulungagung (East Java) and Mengwi (Bali), respectively, from our previous study, were compared.Serological tests for anti‐HEV antibodies by ELISA, HEV‐RNA detection by RT‐PCR and phylogenetic analysis were performed. The total prevalence of anti‐HEV antibodies in humans was higher in Bali(11.6%) than in Java (5.1%; P=0.015). No significant differences in anti‐HEV prevalence among swine farm workers and local residents in Java were found. The finding of swine HEV genotype 3 in specimens from Yogyakarta and genotype 4 from Tulungagung and Bali is somewhat different from other reports.We suggest other factors in addition to close contact with swine might play an important role in HEV transmission of non‐endemic/related custom groups. To the best of our knowledge, this is the first report on swine HEV genotype 3 in Indonesia.
Connectivity-Based Subdivisions of the Human Right "Temporoparietal Junction Area": Evidence for Different Areas Participating in Different Cortical Networks (2011)

Controversy surrounds the role of the temporoparietal junction (TPJ) area of the human brain. Although TPJ has been implicated both in reorienting of attention and social cognition, it is still unclear whether these functions have the same neural basis. Indeed, whether TPJ is a precisely identifiable cortical region or a cluster of subregions with separate functions is still a matter of debate. Here, we examined the structural and functional connectivity of TPJ, testing whether TPJ is a unitary area with a heterogeneous functional connectivity profile or a conglomerate of regions with distinctive connectivity. Diffusion-weighted imaging tractrography-based parcellation identified 3 separate regions in TPJ. Resting-state functional connectivity was then used to establish which cortical networks each of these subregions participates in. A dorsal cluster in the middle part of the inferior parietal lobule showed resting-state functional connectivity with, among other areas, lateral anterior prefrontal cortex. Ventrally, an anterior TPJ cluster interacted with ventral prefrontal cortex and anterior insula, while a posterior TPJ cluster interacted with posterior cingulate, temporal pole, and anterior medial prefrontal cortex. These results indicate that TPJ can be subdivided into subregions on the basis of its structural and functional connectivity.
Register allocation across procedure and module boundaries (1990)

This paper describes a method for compiling programs using interprocedural register allocation. A strategy for handling programs built from multiple modules is presented, as well as algorithms for global variable promotion and register spill code motion. These algorithms attempt to address some of the shortcomings of previous interprocedural register allocation strategies. Results are given for an implementation on a single register file RISC-based architecture.