gebhart/patrepeval huggingface dataset:
Reduced side lobe level of sparse linear antenna array by optimized spacing and excitation amplitude using particle swarm optimization (2017)

Sparse antenna array has many advantages like low mutual coupling, directive beam and cost effective because of less number of elements as compare to equally spaced antenna array. While the main limitation in this array is of high side lobe levels because of different inter element spacing. In this paper optimized values of elements spacing and excitation amplitude for sparse linear antenna array are achieved to minimize the peak side lobe level using particle swarm optimization (PSO) with better convergence rate. Random values of spacing are considered in half and one wave length range. And maintained the main beam direction.
The Met Allele of the BDNF Val66Met Polymorphism Predicts Poor Outcome Among Survivors of Aneurysmal Subarachnoid Hemorrhage (2007)

Genetically influenced variation in BDNF function plays a role in recovery from subarachnoid hemorrhage. These data indicate that augmentation of BDNF signaling may be beneficial to recovery from brain injury.
ChemInform Abstract: STUDIES ON THE CONDENSATION PRODUCTS OF SOME α,β‐UNSATURATED CARBONYL COMPOUNDS WITH 4‐HYDROXYCOUMARIN (1984)

Abstract Aus 4‐Hydroxycumarin (I) und den α,β‐ungesättigten Ketonen (II) entstehen entgegen früheren Literaturangaben die Cyclohalbacetale (III) neben (IVa) bzw. (Vb).
Predictable and distinguishable morphing of vibrotactile rhythm (2017)

Vibrotactile (VT) icons are a ubiquitous, increasingly expressive and expected communicative element of many user interfaces, routinely deployed with technology from rumble motors to novel expressive tactile actuators. However, it is still difficult to design, customize, and experiment with VT feedback. Here we consider manipulation of one of the most salient VT design elements, rhythm, through perceptual morphing. The ability to create perceptual morphs between pairs of VT signal parents expands editorial scope and precision for designers, end-users, and hapticians. To assess perceptual morphs, we propose criteria of predictability - a morph has similarities to one or both parents; and distinguishability - a morph is different from its parents. We developed a new algorithm for perceptual rhythm morphing based on dynamic-time warping (DTW), implemented in an open-source online tool, MacaronMix. Two studies revealed limits and conditions under which DTW-produced VT rhythm morphs are predictable and distinguishable.
An evaluation of the subframe parallel approach for image clustering (1996)

Abstract This paper describes a high‐speed parallel clustering method that is suitable for use as a preprocessor for motion picture compression and coding. In the parallel clustering process, plural pixels are sampled in one frame of an image. Clusters are gathered according to their characteristics, among them, colors, motion vectors, etc., as a way to organize clusters or modify cluster‐parameters in parallel. This operation is repeated until the frame is segmented optimally by a set of clusters. We propose the subframe parallel approach in order to enhance the parallelism of the clustering method and avoid load‐imbalance in parallel tasks. The effectiveness of this approach is also presented and it is shown that a real‐time clustering of motion picture images is available in most cases.
Supplementary Figure 3 from Ionizing Radiation Activates the Nrf2 Antioxidant Response (2023)

Supplementary Figure 3 from Ionizing Radiation Activates the Nrf2 Antioxidant Response
Rosiglitazone increased heart failure but did not differ from metformin plus sulphonylurea for other CV outcomes at interim analysis (2007)

In patients with type 2 diabetes, is rosiglitazone (RGZ) as add on therapy non-inferior to metformin (MFN) plus sulphonylurea (SFU) for cardiovascular (CV) outcomes? Home PD, Pocock SJ, Beck-Nielsen H, et al . Rosiglitazone evaluated for cardiovascular outcomes—an interim analysis. N Engl J Med 2007; 357 :28–38. Clinical impact ratings GP/FP/Primary care ★★★★★★⋆ Cardiology ★★★★★★⋆ Endocrine ★★★★★★⋆ Internal medicine ★★★★★⋆⋆ ### ![Graphic][1]</img>Design: randomised controlled trial (RCT) (Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of glycaemia in Diabetes [RECORD] trial). ### ![Graphic][2]</img>Allocation: unclear allocation concealment.* ### ![Graphic][3]</img>Blinding: blinded (outcome assessors).* ### ![Graphic][4]</img>Follow-up period: mean 3.75 … [1]: /embed/inline-graphic-1.gif [2]: /embed/inline-graphic-2.gif [3]: /embed/inline-graphic-3.gif [4]: /embed/inline-graphic-4.gif
Wideband 15THz response using organic electro-optic polymer emitter-sensor pairs at telecommunication wavelengths (2008)

Poled polymer films are employed in terahertz emission and detection using telecommunication wavelength femtosecond pulses. Films 10–15μm thick with electro-optic coefficients as high as 160pm∕V at 1300nm are used to generate and sense subpicosecond pulses with continuous bandwidth up to 15THz. Terahertz emission from a poled polymer film is compared to terahertz emission from the organic crystal DAST. The use of a poled polymer as the terahertz sensor allows the identification of DAST phonons at 1.1, 3.0, 5.3, 8.5, and 12.5THz.
WebWise: Guide to the Joint Genome Institute Web Site (1998)

The JGI web site presents a centralized information center to disseminate information pertaining to the sequencing
A unimodal fusion framework utilizing multiple enrolment images (2013)

One of the main purposes of using multiple enrolment images in a biometric recognition system is that if the input image is noisy and/or distorted in some way or is deformed during capturing stage, the recognition system may still be able to match with the genuine enrolment image providing more than one option is available. This approach, as used in conventional unimodal recognition systems, attempts to match the input image with multiple enrolment images for each user and select the highest matching score as the correct matching result. However, there exist some inter-dependencies between the data and matching scores which can be exploited not only to enhance the recognition results but also to achieve a better consistency of matching. In this paper we propose an approach to compute and utilize the relationship between the matching scores and hence exploits the computed inter-dependency measures to (i) achieve an improved and stable recognition results and (ii) provide a strong quality measure that can be employed not only to reduce Error Rates but also to act as a parameter that can be used to set weights for multimodal fusion base recognition systems. To demonstrate the effectiveness of the proposed methods, extensive experiments were carried out on fingerprint and iris data using widely used databases.
Coxsackievirus and adenovirus infection. Association with acute febrile and juvenile rheumatoid arthritis (1976)

The prearthritic manifestations of juvenile rheumatoid arthritis in a 16-year-old boy were associated with a rise in coxsackievirus B3 and A9 neutralizing antibody titers from 1:16 to larger than or equal to 1:512, and 1:64 to 1:512, respectively. Recurrent polyarthritis followed and has persisted for three years. Adenovirus 7 was isolated from the pericardial fluid of a 9-year-old girl in whom juvenile rheumatoid arthritis then developed. Of 11 patients with acute, nonspecific, febrile arthritis subsequently studied, fourfold or greater antibody elevations occurred against coxsackieviruses in five, and against rubella and varicella-zoster virus in two. Antibody titers against other viral (and Mycoplasma) antigens remained stable. These findings suggest that coxsackieviruses, as well as other common viruses, may cause acute, nonspecific, febrile arthritis. In certain instances, such infection may be related to the development of juvenile rheumatoid arthritis.
Poly(2-oxazoline)–Pterostilbene Block Copolymer Nanoparticles for Dual-Anticancer Drug Delivery (2017)

Functional block copolymers based on poly(2-oxazoline)s are versatile building blocks for the fabrication of dual-drug delivery nanoparticles (NPs) for anticancer chemotherapy. Core-shell NPs are fabricated from diblock copolymers featuring a long and hydrophilic poly(2-methyl-2-oxazoline) (PMOXA) block coupled to a relatively short and functionalizable poly(2-methylsuccinate-2-oxazoline) (PMestOXA) segment. The PMOXA block stabilizes the NP dispersions, whereas the PMestOXA segment is used to conjugate pterostilbene, a natural bioactive phenolic compound that is used as lipophilic model-drug and constitutes the hydrophobic core of the designed NPs. Subsequent loading of the NPs with clofazimine (CFZ), an inhibitor of the multidrug resistance pumps typically expressed in a large variety of cancer cells, provides an additional function to their formulation. Optimization of the copolymer composition allows the design of polymer scaffolds showing low toxicity and capable of assembling into highly stable NPs dispersions at physiologically relevant pH. In addition, the incorporation of CFZ increases the stability of the NPs and stimulates their internalization by RAW 264.7 cells.
Materiaux piézoélectriques pour moteurs ultrasonores performances requises et problèmes technologiques (1994)

Les moteurs piézoélectriques ultrasonores font depuis plusieurs années l'objet de très nombreuses publications et brevets. La diversité des structures proposées entraîne une grande variété des formes des céramiques piézoélectriques, de leur mode d'excitation et des champs électriques appliqués. Les principales performances requises des matériaux actifs sont présentées tant sur le plan des facteurs de mérites (facteur de couplage, rapport de transformation électromécanique, ... ) que sur celui des pertes ou du vieillissement. Les importants problèmes technologiques posés par certaines structures sont analysés : polarisations inversées dans une même céramique, sérigraphies résistantes, réalisation de liaisons céramiques-métal solides, conductrices et non amorties... Enfin le débouché industriel des moteurs piézoélectriques dépendra essentiellement du coût limite en fabrication de masse des éléments céramiques, piézoélectriques qui restera très lié aux géométries et aux usinages exigés.
Synthesis of diazasteroids II. Synthesis of 8,11‐diaza‐2,3‐dimethoxygona‐1, 3,5 (10), 9 (11)‐tetraene (1973)

Abstract Homoveratrylamine was condensed with 1‐cyanocyclopentene to afford the corresponding 2‐cyano‐ N ‐(3,4‐dimethoxyphenethyl)cyclopentylamine (III), which was ethoxycarbonylated with ethyl chlorocarbonate to give the trans ‐urethan (IVt) (major product) and the cis ‐urethan (IVc) which could be separated through a silica gel column. The cis ‐urethan was converted to the trans ‐urethan by the action of a catalytic amount of sodium ethoxide. Based upon general considerations of nucleophilic addition such as the Michael type reaction, the physical data obtained, and the difference in ease of cyclization of the 2‐aminomethyl‐ N ‐ethoxycarbonyl‐. N ‐homoveratrylcyclopentylamines (Vt and Vc) to the corresponding cyclic ureas (Vlt and VIc), it was concluded that the major product was the trans and the minor the cis isomer. The cyclized compounds, Vlt and VIc, were subsequently submitted to the Bischler‐Napieralski reaction furnishing the corresponding isoquinoline derivatives respectively. Thus the authors established a skeletal synthesis of the title compound, a 8,11‐diazasteroid, and its stereochemical configuration at the C/D ring juncture was elucidated.
[Neuropsychological examinations in childhood]. (1976)

Three groups of children aged 8-12 years have been investigated by a test battery to gain insight into the problems surrounding the relationship between cerebral and behavioral development. One group was of children with circumscribed cortical lesions, one was a group of dyslexics with neurologic anomalies, and the third was a control group of children without brain lesions. General test intelligence did not differ significantly in the three groups. Marked differences between the various lesion groups are observable in some tests but not in others. For example, the results of children with left temporal lesions in the verbal part of the intelligence test and in fresh language memory were inferior to those of all other lesion groups and the controls, while the dyslexics showed a similar if less marked deficit. Non-linguistic (figural) memory did not differ as between groups. On the other hand, children with right frontal lesions were notable for inferior results in a visual learning test and a classification test. In a linguistic-dichotic test all the groups of brain lesions and the dyslexics differed from the control group, a fact which suggests retarded development of hemispheric dominance for speech functions. From these provisional results it can be concluded that the brain areas do not all specialize simultaneously, and that compensation of cerebral lesions in relation to different functions probably results in retardation of overall brain development and anatomico-functional specialization.
Electrical Impedance Tomography problem with inaccurately known boundary and contact impedances (2006)

In electrical impedance tomography (EIT) electric currents are injected into a body with unknown electromagnetic properties through a set of contact electrodes at the boundary of the body. The resulting voltages are measured on the same electrodes and the objective is to reconstruct the unknown conductivity function inside the body based on these data. All the traditional approaches to the reconstruction problem assume that the boundary of the body and the electrode-skin contact impedances are known a priori. However, in clinical experiments one usually lacks the exact knowledge of the boundary and contact impedances, and therefore, approximate model domain and contact impedances have to be used in the image reconstruction. However, it has been noticed that even small errors in the shape of the computation domain or contact impedances can cause large systematic artefacts in the reconstructed images, leading to loss of diagnostically relevant information. In a recent paper (Kolehmainen , 2006), we showed how in the 2-D case the errors induced by the inaccurately known boundary can be eliminated as part of the image reconstruction and introduced a novel method for finding a deformed image of the original isotropic conductivity using the theory of Teichmuller mappings. In this paper, the theory and reconstruction method are extended to include the estimation of unknown contact impedances. The method is implemented numerically and tested with experimental EIT data. The results show that the systematic errors caused by inaccurately known boundary and contact impedances can efficiently be eliminated by the reconstruction method.
Expression Profile of Hexosaminidases Genes in the Brain of Ob/Ob Mice Transplanted with Adipose Tissue (2018)

Purpose: This study aims to assess the expression profile of hexosaminidase genes in the brain of ob/ob mice, to better understand the mechanisms underlying posttranslational protein modifications that leads to Polycystic Ovary Syndrome (PCOS). Glycoproteins assembled within the endoplasmic reticulum carry biological codes determining their fate. Reproduction depends on important glycoproteins and their circulating levels might be affected by leptin.
Methods: B6.V-Lepob/J mice were divided into three groups: Control normal weight; control obese and 7-daytreated obese. Their brains were processed for RNA extraction. PCR Array assays were performed in plates containing 11 mannosidases genes.
Results: Genetic profile of the 7-day group compared to the Control group showed that 82% of the 11 hexosaminidase genes were differentially expressed. These genes were downregulated: Edem1 and 3 can be highlighted. Only two out of six glucosidase-related genes were differentially expressed, Hexa and b, both downregulated.
Conclusion: Leptin alters glycosylation processes of brain molecules pivotal for the malfunctioning of reproductive system, Gene expression levels of hexosaminidases are altered after a seven-day leptin treatment, that causes a gene-expression profile similar to those of the normal weight. Leptin treatment might lead to lower levels of monoglucosylated glycoforms of LH, a hallmark of glycoprotein degradation.
Patient accrual and understanding of informed consent in a two-stage consent design (2021)

We found promising data that two-stage consent facilitated accrual without compromising patient understanding of randomized trials or compliance with allocated treatment. Further research is needed incorporating randomized comparison of two-stage consent to standard consent approaches, measuring patient anxiety and distress as an outcome, using suitable modifications to the Quality of Informed Consent questionnaire and trials with higher stakes.
Continuum Models of Suspension Flow:From Manufacturing to Proppants. (2015)

Abstract not provided.
2-MHz clocked LCD drivers on glass (1990)

A poly-CdSe thin-film transistor (TFT) liquid crystal display (LCD) driver circuit which is integrated on the display itself, reducing the interconnections to the display, is described. The circuit can be used to drive the rows as well as the columns of active and passive matrix LCDs. Drivers made in a 25- mu m technology operate at frequencies up to 2 MHz. Simulations indicate a maximum operating frequency of 8 MHz for a 12.5- mu m technology. By using a time-multiplexing addressing scheme, gray scales can be obtained. In order to address high-resolution displays with gray scales, parallel operating drivers can be used, requiring only one extra connection per parallel driver.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Anthraquinones from Neonauclea calycina and Their Inhibitory Activity against DNA Topoisomerase II. (1998)

In a series of searches for DNA topoisomerase II inhibitors from naturally occurring compounds, a wood extract of Neonauclea calycina MERR. (Rubiaceae) showed a moderate effect in vitro. Purification of the extract resulted in the isolation of seven known anthraquinones. The structures were characterized as damnacanthal, rubiadin 1-methyl ether, nordamnacanthal, morindone, damnacanthol, lucidin 3-O-primeveroside and morindone 6-O-primeveroside by spectral analysis, respectively. Damnacanthal and morindone showed an intensive inhibitory effect against topoisomerase II (IC50: 20 micrograms/ml and 21 micrograms/ml).
Effects of daily consumption of the probiotic Bifidobacterium animalis subsp. lactis CECT 8145 on anthropometric adiposity biomarkers in abdominally obese subjects: a randomized controlled trial (2018)

In abdominally obese individuals, consumption of Ba8145, both as viable and mainly as heat-killed cells, improves anthropometric adiposity biomarkers, particularly in women. An increase in the gut Akkermansia genus appears as a possible mechanism involved. Our results support Ba8145 probiotic as a complementary strategy in obesity management.
Multi-platform bearings-only tracking fusion of maritime targets (2002)

The estimation of target position and velocity is attempted on the basis of angular measurements only. This topic is of interest for passive radar, sonar and electronic warfare systems; in these cases. the maritime target radiates either an electromagnetic or an acoustic wave. The modified gain extended Kalman filter of single platform is used for the tracking of maritime targets, and a fusion algorithm for multi-platform bearing-only tracking is developed. Computer simulations show that the fusion algorithm has better performance than-single platform tracking.
Rab8 Binding to Immune Cell-Specific Adaptor LAX Facilitates Formation of trans -Golgi Network-Proximal CTLA-4 Vesicles for Surface Expression (2014)

Despite playing a central role in tolerance, little is known regarding the mechanism by which intracellular CTLA-4 is shuttled from the trans-Golgi network to the surfaces of T cells. In this context, Ras-related GTPase Rab8 plays an important role in the intracellular transport, while we have previously shown that CTLA-4 binds to the immune cell adaptor TRIM in T cells. In this study, we demonstrate that CTLA-4 forms a multimeric complex comprised of TRIM and related LAX that in turn binds to GTP bound Rab8 for post-Golgi transport to the cell surface. LAX bound via its N terminus to active GTP-Rab8, as well as the cytoplasmic tail of CTLA-4. TRIM required LAX for binding to Rab8 in a complex. Wild-type LAX or its N terminus (residues 1 to 77) increased CTLA-4 surface expression, whereas small interfering RNAs of Rab8 or LAX or disruption of LAX/Rab8 binding reduced numbers of CTLA-4-containing vesicles and its coreceptor surface expression. LAX also promoted the polarization of CTLA-4 and the reorientation of the microtubule-organizing center to the site of T-cell receptor engagement. Our results identify a novel CTLA-4/TRIM/LAX/Rab8 effector complex in the transport of CTLA-4 to the surfaces of T cells.
Meta-analysis of the association of the haptoglobin genotype with cardiovascular outcomes and the pharmacogenomic interactions with vitamin E supplementation (2018)

The Hp genotype is a risk factor for CV events in patients with DM, and administration of vitamin E appears to offer a low cost and accessible means of reducing CV events and mortality in this population.
Novel Therapies Targeting Vascular Endothelium (2006)

Endothelial dysfunction has been identified as a major mechanism involved in all the stages of atherogenesis. Evaluation of endothelial function seems to have a predictive role in humans, and therapeutic interventions improving nitric oxide bioavailability in the vasculature may improve the long-term outcome in healthy individuals, high-risk subjects, or patients with advanced atherosclerosis. Several therapeutic strategies are now available, targeting both the synthesis and oxidative inactivation of nitric oxide (NO) in human vasculature. Statins seem to be currently the most powerful category of these agents, improving endothelial function and decreasing cardiovascular risk after long-term administration. Other cardiovascular agents improving endothelial function in humans are angiotensin-converting enzyme inhibitors/angiotensin receptors blockers, which increase NO bioavailability by modifying the rennin-angiotensin-aldosterone system. Newer therapeutic approaches targeting endothelial dysfunction in specific disease states include insulin sensitizers, L-arginine (the substrate for endothelial NO synthase [eNOS]) as well as substances that target eNOS "coupling," such as folates or tetrahydrobiopterin. Although there are a variety of strategies to improve NO bioavailability in human endothelium, it is still unclear whether they have any direct benefit at a clinical level.
Metatheory and Metamethodology in Marketing: A Lakatosian Reconstruction (1985)

The Lakatosian sophisticated methodological falsification framework is introduced, compared with other philosophies of science, and applied to reconstruct marketing science. From this the location and intensity of extant theoretical conflicts are pinpointed and explained, marketing's scientific status evaluated, and implications for research methodology in the discipline discussed.