gebhart/patrepeval huggingface dataset:
A squeezing experiment showing binder migration in concentrated suspensions (2001)

This paper deals with concentrated suspensions (pastes) of TiO2 particles at a solid concentration of 60% per weight in an acidic binder. This paste is used to manufacture petrochemical catalysts. First we show that in a squeezing experiment binder migration occurs in the suspension as long as the velocity at which the test is carried out does not exceed a critical value. Next, we develop a mathematical model of the test and a complete methodology to identify the rheological parameters of this model. We give an analytical expression of the critical velocity, which is related to the physical characteristics of the suspension. The exact identification of the rheological parameters requires the use of a numerical program which was developed for this application.
Small molecule analogues of the immunomodulatory parasitic helminth product ES-62 have anti-allergy properties (2014)

ES-62, a glycoprotein secreted by the filarial nematode Acanthocheilonema viteae, exhibits anti-inflammatory properties by virtue of covalently attached phosphorylcholine moieties. Screening of a library of ES-62 phosphorylcholine-based small molecule analogues (SMAs) revealed that two compounds, termed 11a and 12b, mirrored the helminth product both in inhibiting mast cell degranulation and cytokine responses in vitro and in preventing ovalbumin-induced Th2-associated airway inflammation and eosinophil infiltration of the lungs in mice. Furthermore, the two SMAs inhibited neutrophil infiltration of the lungs when administered therapeutically. ES-62-SMAs 11a and 12b thus represent starting points for novel drug development for allergies such as asthma.
The Free Haven Project: Distributed Anonymous Storage Service. (2000)

The Free Haven Project is a design for a system of anonymous storage which resists the attempts of powerful adversaries to find or destroy stored data. We explicitly specify requirements for such a storage system and enumerate distinct notions of anonymity. We suggest a way to classify anonymous systems based on the kinds of anonymity provided. Accountability of servers is explicitly addressed through the use of a &amp;quot;trust network,&amp;quot; which attempts to limit the damage done by misbehaving servers. Design choices common to several anonymous storage and publication systems are identified. We end by identifying possible attacks, defenses, and future questions.
Spectrochemical studies on some tetragonal NiL2X2 complexes (1971)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSpectrochemical studies on some tetragonal NiL2X2 complexesRussell S. Drago and Robert L. ChiangCite this: Inorg. Chem. 1971, 10, 3, 453–457Publication Date (Print):March 1, 1971Publication History Published online1 May 2002Published inissue 1 March 1971https://pubs.acs.org/doi/10.1021/ic50097a003https://doi.org/10.1021/ic50097a003research-articleACS PublicationsRequest reuse permissionsArticle Views74Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
STUDY OF THE INFLUENCE BETWEEN BARIUM IONS AND CALCIUM IONS ON MORPHOLOGY AND SIZE OF COPRECIPITATION IN MICROEMULSION (2015)

In this paper, we systematically drew a series of inverse-microemulsion quasi-ternary system phase diagrams of OP -10+ C 8 H 17 OH + C 6 H 12 + brine ( CaCl 2 / BaCl 2 ) by adjusting the ratio of CaCl 2 and BaCl 2 . On this basis, microemulsions have been prepared with seven different molar ratios of Ca 2+ / Ba 2+ , and calcium carbonate and barium carbonate coprecipitation products were obtained by reaction with an equimolar amount of sodium carbonate. The influence of barium ion to morphology and composition of nanometer calcium carbonate were studied. These samples were characterized by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD). The SEM photographs indicated that when the content of Ca 2+ was higher, some incomplete large cube of coprecipitation particles were formed in solution, but with the content of Ba 2+ increased gradually, they formed a large number of small spherical particles, with the further increase of Ba 2+ concentration, the particles mainly had structures of irregular polyhedron eventually. The measurement results of FTIR and XRD indicated that CaCO 3 coprecipitation products gradually changed from calcite to the vaterite, eventually turned into being aragonite with the further increase of Ba 2+ concentration.
CARDIORENAL PROTECTIVE EFFECTS OF PRO-ATRIAL-NATRIURETIC-PEPTIDE (31–67) INDEPENDENT OF BLOOD PRESSURE (2019)

Objective: Cardiac hypertrophy, which accompanies hypertension, is an independent predictor of morbidity and mortality that may progress to heart and kidney failure. Natriuretic peptides secreted by the heart lessen its burden by reducing blood pressure and improving kidney function, as well as by direct actions on cardiac and renal cells. However, the biological activity of the endogenous natriuretic peptides, such as atrial natriuretic peptide (ANP)1–28 and brain natriuretic peptide (BNP)1–32, is diminished, and their protective effects hampered in hypertension and in early stages of heart failure. In the current study, we tested the actions of continuous administration of a linear fragment of ANP, proANP31–67, on blood pressure, kidney and heart function and remodelling. Unlike the ring structured forms, proANP31–67 does not bind to the natriuretic peptide receptors that can cause severe and lethal drops in blood pressure. We tested proANP31–67 in a preclinical model of cardiac hypertrophy induced by hypertension. Design and method: Dahl salt sensitive (Dahl/SS) rats were fed normal (0.3% NaCl) or high (4% NaCl) salt diet. After two weeks, rats were implanted with osmotic mini-pumps for subcutaneous administration of vehicle (untreated) or proANP31-67. Results: Rats receiving vehicle developed hypertension and cardiac hypertrophy. Four weeks treatment with proANP31–67 did not affect hypertension, but exerted protective effects on renal function. ProANP31–67 treated rats had improved urine excretion, increased natriuresis, and enhanced glomerular filtration rate (GFR) compared to untreated hypertensive rats. Importantly, cardiac hypertrophy was also attenuated in treated rats, as indexed by decreased heart weight to body weight ratio and left atrium dimension, as well as reduced fibrosis and normalized E/A ratio. At the cellular level, hearts from Dahl/SS rats showed preserved cardiomyocyte size in treated vs. untreated animals. Moreover, t-tubule density, which was lower in hypertrophied hearts, was preserved in treated animals. Conclusions: These data demonstrate the cardiorenal protective actions of chronic supplementation of a first in class compound, proANP31–67, which preserved kidney and heart structure/function, without reducing systemic blood pressure, in a preclinical model of maladaptive cardiac hypertrophy induced by hypertension.
Uncemented Intramedullary Fixation of Implants Using Polyethylene Sleeves (1992)

Forty-three prostheses with noncemented, high-molecular-weight, polyethylene-sleeved components were used in the treatment of bone tumors around the knee in growing children. The average age of the patients was 11 years. There were 27 boys and 16 girls. There were 17 sleeved components in the distal femur and 26 in the proximal tibia. The average follow-up time was 27 months. The roentgenograms were nominally obtained at three, six, 12, 18, and 24 months, and irregularly thereafter, and were assessed using a zonal evaluation scheme. A sclerotic interface around the polyethylene sleeves invariably developed and progressed in density up to 28 months postoperatively. There were significant zonal differences in sclerosis, particularly between the plateau and the mid-sleeve zone. Only in one patient did a sleeve become loose and require revision.
Convergence of Update Aware Device Scheduling for Federated Learning at the Wireless Edge (2021)

We study federated learning (FL) at the wireless edge, where power-limited devices with local datasets collaboratively train a joint model with the help of a remote parameter server (PS). We assume that the devices are connected to the PS through a bandwidth-limited shared wireless channel. At each iteration of FL, a subset of the devices are scheduled to transmit their local model updates to the PS over orthogonal channel resources, while each participating device must compress its model update to accommodate to its link capacity. We design novel scheduling and resource allocation policies that decide on the subset of the devices to transmit at each round, and how the resources should be allocated among the participating devices, not only based on their channel conditions, but also on the significance of their local model updates. We then establish convergence of a wireless FL algorithm with device scheduling, where devices have limited capacity to convey their messages. The results of numerical experiments show that the proposed scheduling policy, based on both the channel conditions and the significance of the local model updates, provides a better long-term performance than scheduling policies based only on either of the two metrics individually. Furthermore, we observe that when the data is independent and identically distributed (i.i.d.) across devices, selecting a single device at each round provides the best performance, while when the data distribution is non-i.i.d., scheduling multiple devices at each round improves the performance. This observation is verified by the convergence result, which shows that the number of scheduled devices should increase for a less diverse and more biased data distribution.
Genetics of Drug Disposition (2012)

Abstract Drug disposition, a complex process culminating from the interplay of numerous drug–metabolizing enzymes, drug transport proteins, serum‐binding proteins, and transcription factors, is affected by multiple environmental and endogenous factors. Genetic variations in drug–metabolizing enzymes and drug transport proteins contribute toward variability in drug disposition. Our knowledge of these functional genetic variants and the tools to interrogate them are well developed. These tools have found use in drug development within the pharmaceutical industry, and for limited applications, making clinical treatment decisions. This chapter discusses the genetic variations in drug–metabolizing enzymes and transporters and their relevance for clinical pharmacokinetics.
Evaluation of a soft synchronization technique for DS/SS signals (1996)

Soft synchronization of direct-sequence spread-spectrum (DS/SS) signals introduces the capability of despreading with a continuously improving estimate of the spreading code. The soft synchronization technique presented and demonstrated in this paper exploits the eigenstructure of a frequency-channelized DS/SS signal to estimate the code. The estimate improves steadily as more data is collected, resulting in an improved estimate of the message signal. This allows commencement of despreading at an early stage when the code-estimate is still imperfect. Under infinite-time average assumptions a perfect code estimate can be obtained when the signal is received in arbitrary levels of white background noise. This paper demonstrates the synchronization performance of the technique through simulations under finite time-average conditions for environments with fading, multipath, and multi-user interference. The soft synchronization capability is demonstrated. Results show that the technique can remove frequency offsets on the received signal that are integer multiples of the code repeat rate, and that its performance is not degraded by multipath.
Combination of 3D Printing and Electrospinning Techniques for Biofabrication (2022)

Abstract This review presents the different combination methods of 3D printing and electrospinning processes and discusses the advantages of each method. Also, the applications of products of the hybrid process in the biomedical field, including tissue engineering and regenerative medicine, are thoroughly discussed. 3D printing and electrospinning are separate approaches for generating structured materials in a variety of biomedical applications. However, some shortfalls, such as the low resolution of 3D printing and uncontrollable shape of electrospun products, limits their application performances. Therefore, new ideas that combine 3D printing and electrospinning methods are proposed to give full play to their strengths and mitigate their weaknesses, which provide an effective and powerful platform for fabricating novel structural materials. Finally, a future vision regarding challenges and perspectives in the combination of 3D printing and electrospinning techniques is proposed.
Single-Stage, Multimodality Treatment of Soft-Tissue Sarcoma of the Extremity (1997)

The present study describes the techniques available for single-stage sarcoma resection, soft-tissue reconstruction, and radiotherapy for limb preservation in patients who are unable to undergo primary wound closure after a complete soft-tissue resection of their primary sarcoma. From 1989 to 1994, 19 patients (age range, 18-79 years; mean, 51.2 years) underwent radical resection of extremity sarcomas followed by immediate reconstruction. Seven patients had tumors in the upper extremity and 12 patients had tumors in the lower extremity. There were 13 primary tumors and 6 recurrent tumors. Fifteen patients (79%) received radiation therapy, 7 patients by external beam and 8 patients by brachytherapy. Reconstruction included 16 regional flaps in 13 patients and 7 free tissue transfers in 6 patients. Commonly used flaps included the rectus abdominis (N = 5), the latissimus dorsi (N = 4), the anterolateral thigh (N = 4), the reverse-flow radial forearm (N = 2), and the gastrocnemius (N = 2) flaps. Complications included wound breakdown (N = 2), partial skin graft failure (N = 1), hematoma requiring operative evacuation (N = 1), and partial flap necrosis (N = 1). There were no operative mortalities. Eight patients underwent wide local excision, flap closure, and brachytherapy. Mean length of hospital stay for this group was 12.3 days compared with 13.8 days for the remaining 11 patients. There was one complication (13%) in this group and four complications in the remaining patients (4 of 11; 36%). Our study confirms the utility of soft-tissue reconstruction to permit wide local excision with clear margins as well as the delivery of postoperative radiotherapy. It demonstrates the ability of pedicled flaps and free tissue transfers to remain viable and provide sufficient wound coverage in the setting of early postoperative brachytherapy. In addition, this series illustrates the efficacy of a team approach and one-stage therapy for extremity soft-tissue sarcomas that includes excision, reconstruction, and early postoperative brachytherapy in a single hospitalization.
Quantitative particle agglutination assay for point-of-care sensing using mobile holographic imaging and neural networks (2022)

We demonstrate a rapid and cost-effective particle agglutination-based sensor that is powered by holographic imaging and deep learning. A disposable capillary-based flow device is designed to host the agglutination reaction with a material cost of <2 cents/test. A mobile and inexpensive holographic microscope captures a movie of the reaction (~3 min), which is rapidly processed by trained neural networks to automatically measure the target analyte concentration within the sample. The efficacy of this mobile sensor was demonstrated by measuring C-reactive protein (CRP) concentration in human serum samples, accurately covering the high-sensitivity range (0-10µg/mL) and very high concentrations, far exceeding 10µg/mL.
Small Molecules and Stem Cells. Potency and Lineage Commitment: The New Quest for the Fountain of Youth (2010)

ADVERTISEMENT RETURN TO ISSUEPREVPerspectiveNEXTSmall Molecules and Stem Cells. Potency and Lineage Commitment: The New Quest for the Fountain of YouthAgnès I. Lukaszewicz†, Michael K. McMillan†, and Michael Kahn*†‡§View Author Information† Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC‡ Department of Biochemistry and Molecular Biology Keck School of Medicine§ Department of Molecular Pharmacology and Toxicology University of Southern California, 1501 San Pablo Street, Los Angeles, California 90033*To whom correspondence should be addressed. Address: Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, University of Southern California, 1501 San Pablo Street, Los Angeles, CA 90033. Phone: 1-323-442-2063. Fax: 1-323-442-4040. E-mail: [email protected]Cite this: J. Med. Chem. 2010, 53, 9, 3439–3453Publication Date (Web):January 4, 2010Publication History Received14 September 2009Published online4 January 2010Published inissue 13 May 2010https://pubs.acs.org/doi/10.1021/jm901361dhttps://doi.org/10.1021/jm901361dreview-articleACS PublicationsCopyright © 2010 American Chemical SocietyRequest reuse permissionsArticle Views5093Altmetric-Citations29LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Cell signaling,Cells,Differentiation,Genetics,Small molecules Get e-Alerts
Hemostatic properties of glucosamine‐based materials (2006)

Glucosamine- and N-acetyl glucosamine-containing polymers are being used in an increasing number of biomedical applications, including in products for surface (topical) hemostasis. The studies presented here investigate the relationship between the structure (conformation) and function (activation of hemostasis) of glucosamine-based materials. Several polymer systems were studied, including fibers isolated from a microalgal source containing poly-N-acetyl glucosamine polymers that are organized in a parallel, hydrogen-bonded tertiary structure and can be chemically modified to an antiparallel orientation; and gel formulation derivatives of the microalgal fibers consisting of partially deacetylated (F2 gel) and fully deacetylated (F3 gel) polymers. Comparison of the properties of the poly-N-acetyl glucosamine fiber-derived materials with chitin, chitosan, and commercial chitosan-based products are presented. Several studies were performed with the glucosamine-based materials, including (1) an analysis of the ability of materials to activate platelets and turnover of the intrinsic coagulation cascade, (2) an examination of the viscoelastic properties of mixtures of platelet-rich plasma and the glucosamine-based materials via thromboelastography, and (3) scanning electron microscopic studies to examine the morphology of the glucosamine-based materials. The results presented demonstrate that hemostatic responses to the glucosamine-based materials studied are highly dependent on their chemical nature and tertiary/quaternary structure. The unique natural microalgal fibers were found to have strongly prohemostatic activity compared to the other materials studied.
Corneal Damage Thresholds for Hydrogen Fluoride and Deuterium Fluoride Chemical Lasers (1973)

A series of biomedical experiments was performed using the Aerospace Corporation HF/DF chemical lasers to establish corneal damage threshold levels. The DF corneal damage thresholds are higher than the HF thresholds for all conditions tested. Resultant 50%-probability-of-damage values (ED50) for pulsed and continuous wave HF and DF lasers, having specified spectral and pulse characteristics, are expressed with theoretical and safety implications.
Evaluation of user model effectiveness by simulation (2007)

Abstract. Accurate initialization of a User Model (UM) is important for every system that provides personalized services. However, there are systems where this initialization is critical yet no user data is available from prior interactions. For example, one in which both the repeat usage by a user is rare, and the total interaction on a single use is relatively limited. Evaluating the effectiveness of a User Model and a particular instance of such a model is never an easy task, particularly through user studies. Moreover, evaluation typically focuses on the usability of an entire system rather than the performance of a specific UM instantiation. In this paper we propose evaluating the quality of UMs via simulation and comparison to a &amp;amp;quot;gold standard&amp;amp;quot;. This standard is an approximation of the user&amp;apos;s ideal model. We will demonstrate this through a case study of a museum&amp;apos;s visitor guide system implemented in the Hecht Museum at the University of Haifa, Israel
Deep Learning based Oral Cancer Image Classification for Imbalanced Dataset (2020)

We use both data- and algorithm-level methods to improve the neural network performance of oral cancer image classification with imbalanced multi-class dataset captured from high-risk populations during oral cancer screening.
A secure private network file system with minimal system administration (2002)

In this paper, the design and implementation of PNFS, a secure private network file system is demonstrated. On PNFS each user who has an account on a remote machine is permitted to mount remote files without the assistance of the system administrator. This mount operation and the access to the mounted files are kept secured. The evaluation of PNFS is also discussed.
Impression 3D et 4D de matériaux composites à fibres de carbone continues : des applications structurelles au morphing de structures (2019)

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