gebhart/patrepeval huggingface dataset:
[In vivo and in vitro sensitivity to 4-aminoquinolines of Plasmodium falciparum in Madagascar: results of 2 years' study]. (1985)

563 cases of Falciparum malaria were detected in 1984 and 1985 in 7 malarial zones covering 3 climatic regions in Madagascar. All subjects underwent a therapeutic test; 175 strains of Plasmodium falciparum were isolated for in vitro drug sensitivity studies. 28 strains which were moderately chloroquine resistant in vitro were identified in 1983 in these various zones. However, 16% strains studied in 1984 in Alatsinainy (plateaux area), were chloroquine-resistant in vitro. The in vitro sensitivity to the other amino-4-quinolines seemed to be retained. In vivo, 7% of resistance type RI or RII were noted with 25 mg/kg of chloroquine but none with 25 mg/kg of amodiaquine. The usual therapeutic schedule for partially immune subjects (10 mg/kg in one dose) was ineffective on day 7 in 34% of the cases with chloroquine and 5% of the cases with amodiaquine. In conclusion to this study, we recommend that chemoprophylaxis should be stopped in schools in Madagascar and that presumed malarial attacks should be treated with a minimum dose of 25 mg/kg of chloroquine in 3 days. We suggest that amodiaquine should be used in cases of therapeutic failure with chloroquine.
在中国的文化人类学家和教士——大卫·克罗克特·葛维汉（上） (2001)

审校者说明《在中国的文化人类学家和教士——大卫·克罗克特·葛维汉》一文，写的是大卫·克罗克特·葛维汉(David Crockett Graham，1884-1962)在中国四川的人类学活动以及他作为教士的某些活动情况。美国人葛维汉虽然是教士，但他的主要活动在学术方面。他于1911年来华，1913年抵川，直到1948年从成都的华西协和大学退休返国，其间除短期回国述职和……
Letter to Dr. Susan Gerhart (1982)

article Free Access Share on Letter to Dr. Susan Gerhart: comments on two book reviews Author: David Gries Cornell University, Ithaca, NY Cornell University, Ithaca, NYView Profile Authors Info & Claims ACM SIGSOFT Software Engineering NotesVolume 7Issue 3July 1982 pp 30–32https://doi.org/10.1145/1010904.1010911Online:01 July 1982Publication History 0citation105DownloadsMetricsTotal Citations0Total Downloads105Last 12 Months2Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Measurement of compensatory reserve predicts racial differences in tolerance to simulated hemorrhage in women (2018)

Diagnostic test, level II.
[Effect of DOC/CCRT Aging on Gaseous Emission Characteristics of an In-used Diesel Engine Bus]. (2016)

Based on heavy chassis dynamometer, an experimental study was conducted in diesel bus with China Stage Ⅲ, which investigated the effects of gaseous emission characteristics under CCBC driving cycle, such as carbon monoxide (CO), total hydrocarbons (THC), nitric oxide (NO), nitrogen dioxide (NO<sub>2</sub>), nitrogen oxides (NO<sub><i>x</i></sub>) and carbon dioxide (CO<sub>2</sub>) with the fresh/aged oxidized catalyst (DOC) and oxidation catalysts coupled catalyzed particulate trap (DOC+CDPF, referred CCRT). The results showed that using fresh and aged DOC/CCRT, the diesel bus could reduce CO, THC and NO emissions, meanwhile increase NO<sub>2</sub> emissions, but NO<sub><i>x</i></sub> and CO<sub>2</sub> emissions remained basically unchanged. In idle speed, acceleration, deceleration and constant speed of working conditions, the diesel bus using the fresh DOC had better oxidation efficiency of the CO and THC emissions than the bus using the aged DOC. The diesel bus using the fresh CCRT had higher oxidation efficiency of THC emissions, but lower oxidation efficiency of CO emissions than the bus using the aged CCRT. The diesel bus using the fresh DOC/CCRT had a higher rate of NO emissions reductions and NO<sub>2</sub> emissions increments than the bus using the aged DOC/CCRT, but it did not basically affect the NO<sub><i>x</i></sub> emissions.
A Study on Pitch Detection of Sinusoidal Noise for Noise Reduction System (2006)

A noise reduction system based on an adaptive line enhancer (ALE) and noise estimation filter (NEF) has been proposed in order to reduce both wideband and sinusoidal noise in noisy speech. The noise reduction system has the ALE with less the computation load. However, the ALE needs a pitch detector of sinusoidal noise. In this paper, a pitch period detection using the tap coefficients of the ALE for estimating the sinusoidal noise is proposed. The proposed method can detect the pitch period of sinusoidal noise superposed on speech
An Agent-based Approach to Grid Service Monitoring (2001)

The centralised management of distributed computing infrastructures presents a number of considerable challenges, not least of which is the effective monitoring of physical resources and middleware components to provide an accurate operational picture for use by administrative or management staff. The detection and presentation of real-time information pertaining to the performance and availability of computing resources is a difficult yet critical activity.
 This architecture is intended to enhance the service monitoring experience of a Grid operations team. We have designed and implemented an extensible agent-based architecture capable of detecting and aggregating status information using low-level sensors, functionality tests and existing information systems. To date it has been successfully deployed across eighteen Grid-Ireland sites.
Selective Diagnosis of Diabetes Using Pt-Functionalized WO3 Hemitube Networks As a Sensing Layer of Acetone in Exhaled Breath (2012)

Thin-walled WO(3) hemitubes and catalytic Pt-functionalized WO(3) hemitubes were synthesized via a polymeric fiber-templating route and used as exhaled breath sensing layers for potential diagnosis of halitosis and diabetes through the detection of H(2)S and CH(3)COCH(3), respectively. Pt-functionalized WO(3) hemitubes with wall thickness of 60 nm exhibited superior acetone sensitivity (R(air)/R(gas) = 4.11 at 2 ppm) with negligible H(2)S response, and pristine WO(3) hemitubes showed a 4.90-fold sensitivity toward H(2)S with minimal acetone-sensing characteristics. The detection limit (R(air)/R(gas)) of the fabricated sensors with Pt-functionalized WO(3) hemitubes was 1.31 for acetone of 120 ppb, and pristine WO(3) hemitubes showed a gas response of 1.23 at 120 ppb of H(2)S. Long-term stability tests revealed that the remarkable selectivity has been maintained after aging for 7 months in air. The superior cross-sensitivity and response to H(2)S and acetone gas offer a potential platform for application in diabetes and halitosis diagnosis.
Rheology and Shear‐Induced Textures of Silver Nanowire Lyotropic Liquid Crystals (2015)

We report the rheological and microstructural shear response of a mixture of polyvinylpyrrolidone (PVP) coated silver nanowires and nanoparticle aggregates (Ag) dispersed in ethylene glycol (EG) or water (H 2 O). Biphasic and liquid crystalline dispersions exhibited rheological characteristics similar to those of lyotropic liquid crystalline polymers (LCPs). The viscosity versus concentration curve for Ag‐EG dispersions showed a viscosity minimum at a silver concentration between 2.2 vol.% and 2.9 vol.%; this is indicative of the transition to an entirely liquid crystalline phase. The rheology results were consistent with optical microscopy observations that at 2.9 vol.% the sample was entirely birefringent; this is another indication of liquid crystalline phase formation. Shear had a significant effect on the microstructure of the dispersions and dried coatings. Depending on the shear rate, worm or shear banding Structures were observed.
Methotrexate analogs. 12. Synthesis and biological properties of some aza homologs (1979)

Methotrexate analogues, in which an additional nitrogen atom is inserted between the phenyl ring and the carbonyl group of the side chain, were prepared by photochemical methods. The compounds were less inhibitory toward dihydrofolate reductase and thymidylate synthetase derived from Lactobacillus casei than was methotrexate. They were also less cytotoxic against human lymphoblastic leukemia cells (CCRF-CEM). In vivo against L-1210 leukemia in mice, the aza homologue of methotrexate showed significant antitumor activity (%ILS = 55%) compared to methotrexate (%ILS = 88%).
A Fully Differential Monolithic LNA With On-Chip Antenna for a Short Range Wireless Receiver (2009)

This letter presents the smallest reported 5 GHz receiver chip (1.3 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> ) with an on-chip antenna in standard 0.13 mum CMOS process. The miniaturization is achieved by placing the circuits inside a meandered antenna. The on-chip antenna is conjugately matched to the low noise amplifier (LNA) over a wide frequency range. The design methodology for co-design of the on-chip antenna and LNA is described. The LNA is completely differential, consumes only 8 mW of power and provides a gain of 21 dB. Design tradeoffs and measurement challenges are given.
Simulation of gate switching characteristics of a miniaturized MOSFET based on a non-isothermal non-equilibrium transport model (2002)

Our device simulator is developed for the analysis of a MOSFET based on a thermally coupled energy transport model (TCETM). The simulator has the ability to calculate not only steady-state characteristics but also transient characteristics of a MOSFET. It solves basic semiconductor device equations including the Poisson equation, current continuity equations for electrons and holes, energy balance equation for electrons and heat flow equation, using the finite difference method.
Systematic trends in the electronic structure parameters of the4dtransition-metal oxidesSrMO3(M=Zr,Mo, Ru, and Rh) (2003)

We investigated the electronic structures of the perovskite-type $4d$ transition-metal oxides $\mathrm{Sr}M{\mathrm{O}}_{3}$ $(M=\mathrm{Zr},$ Mo, Ru, and Rh) using their optical conductivity spectra $\ensuremath{\sigma}(\ensuremath{\omega}).$ The interband transitions in $\ensuremath{\sigma}(\ensuremath{\omega})$ are assigned, and some important electronic structure parameters, such as charge-transfer energy ${\ensuremath{\Delta}}_{\mathrm{pd}},$ and crystal-field splitting $10Dq,$ are estimated. It is observed that ${\ensuremath{\Delta}}_{\mathrm{pd}}$ and $10Dq$ decrease systematically with increasing the atomic number of the $4d$ transition metal. Compared with the case of $3d$ oxides, the magnitudes of ${\ensuremath{\Delta}}_{\mathrm{pd}}$ and $10Dq$ are larger. These behaviors can be explained by the more extended nature of the orbitals in the $4d$ oxides.
Scene Segmentation Assisted by Stereo Vision (2011)

Stereo vision systems for 3D reconstruction have been deeply studied and are nowadays capable to provide a reasonably accurate estimate of the 3D geometry of a framed scene. They are commonly used to merely extract the 3D structure of the scene. However, a great variety of applications is not interested in the geometry itself, but rather in scene analysis operations, among which scene segmentation is a very important one. Classically, scene segmentation has been tackled by means of color information only, but it turns out to be a badly conditioned image processing operation which remains very challenging. This paper proposes a new framework for scene segmentation where color information is assisted by 3D geometry data, obtained by stereo vision techniques. This approach resembles in some way what happens inside our brain, where the two different views coming from the eyes are used to recognize the various object in the scene and by exploiting a pair of images instead of just one allows to greatly improve the segmentation quality and robustness. Clearly the performance of the approach is dependent on the specific stereo vision algorithm used in order to extract the geometry information. This paper investigates which stereo vision algorithms are best suited to this kind of analysis. Experimental results confirm the effectiveness of the proposed framework and allow to properly rank stereo vision systems on the basis of their performances when applied to the scene segmentation problem.
Association of body mass index with morbidity following elective ventral hernia repair (2023)

Body mass index (BMI) continues to be a relevant factor in morbidity and resource use for elective open ventral hernia repair (VHR). A BMI of 32 serves as the threshold for significant increase in overall complications following open VHR, though this association is not observed in operations performed laparoscopically.
Tandem Mass Spectrometry Analysis of N2-(trans-Isoestragol-3‘-yl)-2‘-deoxyguanosine as a Strategy to Study Species Differences in Sulfotransferase Conversion of the Proximate Carcinogen 1‘-Hydroxyestragole (2007)

To get more insight into possible species differences in the bioactivation of estragole, the kinetics for sulfonation of the proximate carcinogen 1'-hydroxyestragole were compared for male rat, male mouse, and mixed gender human liver S9 homogenates. In order to quantify sulfonation, 2'-deoxyguanosine was added to the incubation mixture in which sulfonation of 1'-hydroxyestragole was catalyzed to trap the reactive 1'-sulfooxyestragole. A method was developed with which the formation of the most abundant adduct with 2'-deoxyguanosine could be quantified using isotope dilution LC-ESI-MS/MS. Comparing the kinetics for sulfonation by liver S9 homogenates of male rat, male mouse, and humans revealed that sulfonation was about 30 times more efficient by male rat liver S9 than by human liver S9, whereas the catalytic efficiency by male mouse and human liver S9 was about the same. This indicates, as far as the bioactivation by sulfotransferase is concerned, that when extrapolating the cancer risk from laboratory animals to humans, using data from male rats may overestimate the cancer risk in humans, whereas using data from male mice may provide a better estimate of the cancer risk in humans.
Constitutive modelling of the creep behaviour of single crystal superalloys under non-isothermal conditions inducing phase transformations (2010)

International audience
Experimental demonstrations of RoF technologies for 5G indoor DAS applications (2018)

We present the RoF based indoor DAS prototype for mmWave based 5G mobile communication system. It's technical feasibilities including optical transmission performances and various electrical/optical characteristics are experimentally confirmed.
评施拉佩托格著: 《苏联知识分子与政权:后斯大林时代》 (1993)

本文作者志在考察苏联制度下知识分子的政治作用,可惜志大才疏,力不从心。虽然如此,一幅清晰的苏联知识分子生活画面呈现在读者面前,往往令人爱不释手。作者的中心论点是:自斯大林逝世至80年代后期,苏联的主要反对力量是知识分子,虽然他也尽力指出“伪”知识分子的合作态度以及更著名的知识界人士与官方沆瀣一气的例子。的确,这本著作的力量就在于此,它的独到的手法突出
A Novel Approach to Exponential Speedup of Simulation Events in Wireless Networks (2018)

We demonstrate a new approach that yields exponential speedup of communication events in discrete event simulations (DES) of mobile wireless networks. With the trending explosive growth of wireless devices including Internet of things devices, it is important to have the capability to simulate wireless networks at large scale accurately. Unfortunately, current simulation techniques are inadequate for large-scale network simulation especially at high rate of total transmission events due to poor performance scaling. This has limited many studies to much smaller sizes than desired. We propose a method for attaining high fidelity DES of mobile wireless networks that leverages (i) path loss of transmissions and (ii) the relatively slower topology changes in a high transmission rate environment. Our approach averages a runtime of k(r)O(log N) per event, where N is the number of simulated wireless nodes, r is a factor of maximum transmission range, and k(r) is typically constant obeying k(r)≪ N.
Natural selection fails to optimize mutation rates for long-term adaptation on rugged fitness landscapes (2013)

The rate of mutation is central to evolution. Mutations are required for adaptation, yet most mutations with phenotypic effects are deleterious. As a consequence, the mutation rate that maximizes adaptation will be some intermediate value. Here, we used digital organisms to investigate the ability of natural selection to adjust and optimize mutation rates. We assessed the optimal mutation rate by empirically determining what mutation rate produced the highest rate of adaptation. Then, we allowed mutation rates to evolve, and we evaluated the proximity to the optimum. Although we chose conditions favorable for mutation rate optimization, the evolved rates were invariably far below the optimum across a wide range of experimental parameter settings. We hypothesized that the reason that mutation rates evolved to be suboptimal was the ruggedness of fitness landscapes. To test this hypothesis, we created a simplified landscape without any fitness valleys and found that, in such conditions, populations evolved near-optimal mutation rates. In contrast, when fitness valleys were added to this simple landscape, the ability of evolving populations to find the optimal mutation rate was lost. We conclude that rugged fitness landscapes can prevent the evolution of mutation rates that are optimal for long-term adaptation. This finding has important implications for applied evolutionary research in both biological and computational realms.
Językoznawstwo polonistyczne na Uniwersytecie Jagiellońskim dawniej i dziś (w 10 rocznicę powstania Wydziału Polonistyki UJ) (2018)

Polish linguistics at the Jagiellonian University then and now (on the tenth anniversary of the creation of the Faculty of Polish Studies)&#x0D; The paper presents a synthesis of the history and achievements of Polish linguistics cultivated at the Jagiellonian University since the second half of the 19th century till this day. The beginnings are the first lectures which discussed the Polish language, followed by the creation of chairs, then the institute, and finally a separate Faculty of Polish Studies. The author interweaves the institutional and personal threads, and indicates the most important figures of old professors whose works were central to the development of Polish linguistics and its various fields.
Block Encryption Using Hybrid Additive Cellular Automata (2007)

With the ever-increasing growth of data communication, the need for security and privacy has become a strong necessity. In these conditions, the necessity of new powerful encryption techniques becomes a crucial issue. In this paper Cellular Automata (CA) are applied to construct cryptography algorithms. We present an encryption system implemented on a structure of Hybrid Additive Cellular Automata (HACA) used for securing the medical data sent over the internet. The experimental results prove the power of cellular automata encryption systems. The method supports both software and hardware implementation. In this paper we present a fully functional software application for the data encryption of multimedia medical content.
10nm-diameter tri-gate silicon nanowire MOSFETs with enhanced high-field transport and V<inf>th</inf> tunability through thin BOX (2012)

We demonstrate high-performance 10nm-diameter tri-gate nanowire transistors (NW Tr.) with V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">th</sub> tunability, small variability and negligible self-heating. Optimized S/D and stress memorization technique (SMT) lead to significant parasitic resistance reduction and mobility enhancement. Saturation velocity increase by SMT further enhances high-field carrier velocity and I <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">on</sub> of 1mA/μm at I <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">off</sub> of 100nA/μm is achieved. We also demonstrate V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">th</sub> control in tri-gate NW Tr. with thin BOX for the first time. The degradation of body effect by NW narrowing can be recovered by thinning NW height, enabling dynamic power and performance management.
Structure–function analysis of a new PL17 oligoalginate lyase from the marine bacterium Zobellia galactanivorans DsijT (2021)

Alginate is a major compound of brown macroalgae and as such an important carbon and energy source for heterotrophic marine bacteria. Despite the rather simple composition of alginate only comprising mannuronate and guluronate units, these bacteria feature complex alginolytic systems that can contain up to seven alginate lyases. This reflects the necessity of large enzyme systems for the complete degradation of the abundant substrate. Numerous alginate lyases have been characterized. They belong to different polysaccharide lyase (PL) families, but only one crystal structure of a family 17 (PL17) alginate lyase has been reported to date, namely Alg17c from the gammaproteobacterium Saccharophagus degradans. Biochemical and structural characterizations are helpful to link sequence profiles to function, evolution of functions and niche-specific characteristics. Here, we combined detailed biochemical and crystallographic analysis of AlyA3, a PL17 alginate lyase from the marine flavobacteria Zobellia galactanivorans DsijT, providing the first structure of a PL17 in the Bacteroidetes phylum. AlyA3 is exo-lytic and highly specific of mannuronate stretches. As part of an "alginate utilizing locus", its activity is complementary to that of other characterized alginate lyases from the same bacterium. Structural comparison with Alg17c highlights a common mode of action for exo-lytic cleavage of the substrate, strengthening our understanding of the PL17 catalytic mechanism. We show that unlike Alg17c, AlyA3 contains an inserted flexible loop at the entrance to the catalytic groove, likely involved in substrate recognition, processivity and turn over.
Endobronchial Eosinophilic Granuloma: A Rare Cause of Total Lung Atelectasis (1987)

A 12-yr-old male presented with left lung atelectasis secondary to a mainstem endobronchial mass. At thoracotomy, a left mainstem bronchial sleeve resection successfully extirpated what later proved to be an eosinophilic granuloma. This is the first case report, to our knowledge, of endobronchial eosinophilic granuloma.