gebhart/patrepeval huggingface dataset:
Players’ Physical Performance Decreased After Two-Thirds of the Season: Results of 3 Consecutive Seasons in the German First Bundesliga (2019)

The study aimed to: (1) investigate physical and technical performance among players during six consecutive phases of a competitive season, (2) determine if levels of match running and technical performance between the 1st and 6th phases of a season can be maintained, (3) and determine which phase features the lowest and highest values for variables assessed. Seventy out of 556 outfield players who played at least 80% of the matches in each phase of the Bundesliga seasons were analysed. Each season was divided into 6 phases: phase 1 (matches 1-6), phase 2 (7-11), phase 3 (12-17), phase 4 (18-23), phase 5 (24-28) and phase 6 (29-34). Thirteen variables were selected to quantify the physical and technical activity of players. Our results showed that by reducing the distances covered at intensities below 11 km·h<sup>-1</sup>, players were able to cover greater distances at intensities in the range of 11-13.99 and 21-23.99 km·h<sup>-1</sup> in subsequent phases of a season. Players' capacity to maintain match running and technical performance between the first and sixth phases of the season has been demonstrated, though the 4th phase of the season showed a breakthrough point as regards the maintenance of exercise capacity among players participating in the Bundesliga.
Haematopoietic stem cell transplantation in systemic sclerosis (2018)

Three randomised controlled trials of haematopoietic stem cell transplantation (HSCT) in systemic sclerosis (SSc) demonstrated long-term survival benefits, induction of clinically meaningful, sustained improvement of forced vital capacity with improvements in skin thickening, vasculopathy and health-related quality of life, in contrast to a clinical decline in standard of care control groups. These benefits, however, must be weighed against the increased risk of transplant-related mortality. Further, with disease progression, severe extensive internal organ involvement and damage ensues, constituting an exclusion criterion for safety reasons, leaving a limited window whereby patients with SSc are eligible for HSCT. Although autologous HSCT offers the possibility of drug-free remission, relapse can occur, requiring re-initiation of disease modifying antirheumatic drugs. HSCT is also associated with secondary autoimmune diseases and gonadal failure. HSCT should be proposed for carefully selected patients with early rapidly progressive diffuse SSc whose clinical picture portends a poor prognosis for survival, but yet lacks advanced organ involvement.
Nonlinear Block Copolymers (2002)

Chapter 8 describes the wide range of synthetic methodologies usually employed for the synthesis of block copolymers having non-linear architectures. The synthesis of complex architectures includes the preparation of star block copolymers, miktoarm star copolymers, graft copolymers, cyclic copolymers and combination of these as the block-graft and dumdbell architectures. The general strategies followed, irrespective of the polymerization mechanism used, are described. The advantages and drawbacks of each one of them are discussed and comparisons are made using examples from the literature.
Induction of robust antitumor immunity by exogenous interleukin-33 (TUM2P.1005) (2015)

Abstract IL-33 is associated with the induction of Th2-type immunity, however it has recently gained attention for its role in boosting Th1-type immunity and CD8+ T cell function. We have discovered that IL-33 can induce robust antitumor effect through a CD8+ T cell dependent mechanism. Systemic administration of recombinant IL-33 (rIL-33) alone was sufficient to inhibit growth of established tumors in multiple mouse tumor models. Notably, rIL-33 treatment promoted antitumor CD8+ T cell expansion and effector function. Mechanistically, rIL-33 therapy primarily and directly targets dendritic cells in tumor bearing mice, thereby restores CTL activity by increasing antigen cross-presentation within the tumor microenvironment. Furthermore, agonist activation of CD40, which is induced by rIL-33 treatment, stabilized and induced regression of established tumors. Our study has elucidated the potential use of rIL-33 as a novel immunotherapy option for the treatment of established cancers.
Supporting speculative parallelization in the presence of dynamic data structures (2010)

The availability of multicore processors has led to significant interest in compiler techniques for speculative parallelization of sequential programs. Isolation of speculative state from non-speculative state forms the basis of such speculative techniques as this separation enables recovery from misspeculations. In our prior work on CorD [35,36] we showed that for array and scalar variable based programs copying of data between speculative and non-speculative memory can be highly optimized to support state separation that yields significant speedups on multicore machines available today. However, we observe that in context of heap-intensive programs that operate on linked dynamic data structures, state separation based speculative parallelization poses many challenges. The copying of data structures from non-speculative to speculative state (copy-in operation) can be very expensive due to the large sizes of dynamic data structures. The copying of updated data structures from speculative state to non-speculative state (copy-out operation) is made complex due to the changes in the shape and size of the dynamic data structure made by the speculative computation. In addition, we must contend with the need to translate pointers internal to dynamic data structures between their non-speculative and speculative memory addresses. In this paper we develop an augmented design for the representation of dynamic data structures such that all of the above operations can be performed efficiently. Our experiments demonstrate significant speedups on a real machine for a set of programs that make extensive use of heap based dynamic data structures.
Mapping of P4 match action tables to FPGA (2017)

Current networks are changing very fast. Network administrators need more flexible and powerful tools to be able to support new protocols or services very fast. The P4 language provides new level of abstraction for flexible packet processing. Therefore, we have designed new architecture for memory efficient mapping of P4 match/action tables to FPGA. The architecture is based on DCFL algorithm and is able to balance the processing speed and available memory resources.
Subject‐specific models of susceptibility‐induced B0 field variations in breast MRI (2012)

The computed field maps had substantial overall agreement with the measured field maps, indicating that breast MRI field maps can be computed based on the air-tissue interfaces. These estimates may provide a predictive model for field variations and thus have the potential to improve applications in breast MRI.
Characterization of a bimodal multi-fibre optic clinical probe for in situ tissue diagnosis based on spectrally-and temporally-resolved autofluorescence (2023)

Introduction: Fibred-based optical spectroscopy is advantageous over imaging due to its sensitivity, practicality and precision, providing point of care diagnosis. The unique advantage is that the sampled volume is well defined by the source-detector geometry and that the functionality of multiple optical techniques can be incorporated into one probe so that more information is gained without extra bulkiness or cost, while also mitigating the limitations of each. Methods: This advantage is utilized here to address the limited accuracy in delineating brain tumors, in situ, by simultaneously characterizing tissue based on the spectral and lifetime properties of five endogenous fluorophores commonly present in brain tissue. A 5-meters multi fibre-optic probe custom-built for neurosurgery guidance with a sterilizable distal end is presented in this paper. It describes its technical features such as architecture, collection efficiency, sensitivity. Results and discussion: The developed probe have a temporal resolution of 34.6 ps and a temporal impulse response function of 29 ps. The spatial resolution was around 153 μm while the spectral resolution is 1 nm. All of these specifications are ensured under 1 second as acquisition time. The probe is validated using fluorescent dyes and tissue phantoms. Additionally, the fluorescence spectra from fresh and frozen animal tissue and from an epileptic patient are compared to that obtained from confocal fluorescence microscopy, while the lifetime values are compared to that reported in literature. Finally, the effect of pressure applied to the probe in contact with tissue is discussed.
A Triple-Stain Flow Cytometric Method to Assess Plasma- and Acrosome-Membrane Integrity of Cryopreserved Bovine Sperm Immediately after Thawing in Presence of Egg-Yolk Particles1 (2003)

Simultaneously evaluating postthaw viability and acrosome integrity of spermatozoa by flow cytometry would provide a valuable testing tool in both research and routine work. In the present study, a new triple-stain combination was developed for the simultaneous evaluation of viability and acrosome integrity of bovine sperm processed in egg yolk-based extender by flow cytometer. SYBR-14 and propidium iodide (PI) enabled the discrimination of sperm cells from egg yolk and debris particles, which was instrumental for the flow cytometric analyses of frozen-thawed bovine sperm, because it implied that washing steps to remove egg yolk were no longer required. In addition, phycoerythrin-conjugated peanut agglutinin (PE-PNA) was used to discriminate acrosome-damaged/reacted sperm cells from acrosome-intact cells. Repeatability was calculated using two processed ejaculates of 10 bulls. Three straws per batch were analyzed in duplicate measurements. Method-agreement analysis between the SYBR-14/PE-PNA/PI and fluorescein isothiocyanate (FITC)-conjugated PNA was performed, with FITC-PNA/PI staining being carried out on 14 frozen-thawed semen samples immediately after thawing and after a 3-h incubation at 37 degrees C. The British Standards Institution repeatability index of the SYBR-14/PE-PNA/PI combination was 2.6%. On average, the FITC-PNA/PI method showed a 6.3% overestimation of the live and acrosome-intact sperm cell subpopulation. In conclusion, the new triple-stain combination is highly repeatable and easy to use in routine application, and it provides a more precise estimate for the rate of sperm cells with intact head membrane and acrosome compared to the generally used and validated FITC-PNA/PI staining.
Diffusion-Limited Photophysical Interactions as in situ Probes of Conversion in Free Radical Polymerization: Quantitative Analysis with Predictive Free-Volume Theory (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDiffusion-Limited Photophysical Interactions as in situ Probes of Conversion in Free Radical Polymerization: Quantitative Analysis with Predictive Free-Volume TheoryMarc B. Wisnudel and John M. TorkelsonCite this: Macromolecules 1994, 27, 24, 7217–7219Publication Date (Print):November 1, 1994Publication History Published online1 May 2002Published inissue 1 November 1994https://pubs.acs.org/doi/10.1021/ma00102a035https://doi.org/10.1021/ma00102a035research-articleACS PublicationsRequest reuse permissionsArticle Views74Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Super continuum generation for real time ultrahigh resolution optical coherence tomography (2006)

Optical coherence tomography (OCT) is an emerging technology for micrometer-scale, cross-sectional imaging of biological tissue and materials. One of the key limitations to achieving ultrahigh-resolution OCT imaging outside the laboratory setting has been the lack of compact, high-performance broadband light sources with sufficient power and stability to allow practical real-time imaging. The broad-bandwidth supercontinuum (SC) sources were recently demonstrated with femtosecond lasers in combination with nonlinear fibers. Using SC, we can demonstrate ultrahigh resolution OCT. However, wideband SC generally has large excess noise and significant fine structure. Low noise and smooth spectral shape are desired in the ideal supercontinnum source. In this paper, we describe recent studies on practical SC generation for ultrahigh-resolution OCT. SC generation is first analyzed both numerically and experimentally in terms of OCT imaging requirements and optimized conditions for generation are discussed. Supercontinua generated by use of highly nonlinear fiber which have a zero-dispersion wavelength near the pump wavelength, generally result in severe spectral modulation and fluctuating fine structure in the spectra. This spectral modulation produces sidelobes and reduced contrast in the interferometric point-spread function. In contrast, normally dispersive, highly nonlinear fibers (ND-HNFs) can generate smooth and Gaussian shaped supercontinua by the combination of self-phase modulation and normal dispersion. Low noise and wideband SC generation is demonstrated using ND-HNFs. Two colored SC generation is also demonstrated using a photonic crystal fiber which has two close zero dispersion wavelengths. The numerical results are almost in agreement with the experimental ones. Finally, low noise SC generation is demonstrated in an all fiber system based on an ultrashort pulse fiber laser. Wideband, low noise, near Gaussian shaped, high power SC is generated in the 1.55 &#956;m wavelength region. In vivo, high-speed OCT imaging of human skin with ~5.5 &#956;m resolution and 99 dB sensitivity is demonstrated.
Clay Catalysed Convenient Isomerization of Natural Furofuran Lignans Under Microwave Irradiation (2000)

Abstract The naturally occuring furofuron lignans, (+)-sesamin, (+)-eudesmin, (+)-syringaresinol and (+)-yangambin underwent rapid isomerization to their corresponding C-7 epimers under microwave irradiation in the presence of montmorillonite KSF as catalyst.
Shape anisotropic magnetic thrombolytic actuators: synthesis and systematic behavior study (2021)

Thrombosis-related diseases are undoubtedly the deadliest disorders. During the last decades, numerous attempts were made to reduce the overall death rate and severe complications caused by treatment delays. Significant progress has been made in the development of nanostructured thrombolytics, especially magnetically controlled. The emergence of thrombolytic magnetic actuators, which can deliver tPA to the occlusion zone and perform mechanical disruption of the fibrin network under the application of a rotating magnetic field (RMF), can be considered for the next generation of thrombolytic drugs. Thus, we propose a systematic study of magnetic-field mediated mechanically-assisted thrombolysis (MFMMAT) for the first time. Four types of magnetic particles with different morphology and dimensionality were utilized to assess their impact on model clot lysis under different RMF parameters. Chain-like 1D and sea urchins-like 3D structures were found to be the most effective, increasing thrombolysis efficacy to nearly 200%. The drastic difference was also observed during the dissolution of 3 days old blood clots. Pure plasminogen activator had almost no effect on clot structure during 30 minutes of treatment while applying MFMMAT led to the significant decrease of clot area, thus uncovering the possibility of deep venous thrombosis therapy.
Safety and efficacy of a Labisia pumila var alata water extract on sexual well being and lipid profile of pre- and postmenopausal women: A randomized double-blind pilot study (2014)

This randomized double-blind, placebo-controlled study investigated the safety and efficacy of Labisia pumila (LP) water extract on sexual health, lipid profile and inflammatory markers in 36 healthy pre-and post-menopausal North American women. Participants were randomized to either LP (200 mg) or placebo for 12 weeks. The female sexual function index (FSFI) and short form-36 health survey (SF-36) were completed, and lipid profiles, anti-inflammatory markers, urinary antioxidants and safety parameters were assessed. There were no significant differences in FSFI and SF-36 scores after 12 weeks. Compared to placebo, women on Labisia pumila trended towards a reduction in total cholesterol after 12 weeks (p=0.077). Urinary 8-isoprostane concentrations from baseline to week 12 decreased for both groups, with women on L. pumila demonstrating a greater decrease (&Delta;= -144.4nmol/L) versus placebo (&Delta;= -125.9nmol/L). Significant decreases in serum IL-6 from baseline to week 6 were observed in Labisia pumila and placebo (p=0.006 and p=0.012 respectively) but these differences were not sustained through week 12. LP demonstrated a trend towards an improvement in TC, urinary 8-isoprostane and significant within group improvement in IL-6 and IL-1&beta; suggesting a role for LP in improving inflammation. Future research should focus on older subjects that are sexually dysfunctional. &nbsp; Key words: Labisia pumila, women&rsquo;s health, randomized double-blind trial, female sexual function index, blood lipid profile, cytokines.
Analysis of Defective Hydrostatic Radial Bearings for Five Megajoule Homopolar Generator (1980)

Hydrostatic bearings were designed for a five megajoule homopolar generator since they offered the advantages of low shaft friction, high load capacity and high stiffness independent of shaft speed. The original bearings were satisfactory except for electrical pitting. A redesign using a high pressure laminated (G-9) fiberglass cloth reinforced melamine-formaldehyde resin composite resulted in a defective design. Design parameters are given with a complete analysis showing where the design was defective along with a satisfactory solution used in a subsequent redesign.
Pricing Based Distributed Traffic Allocation for 5G Heterogeneous Networks (2020)

Next generation (5G and beyond) mobile networks will highly rely on distributed heterogeneous infrastructure, which is foreseen to create a versatile resource ecosystem. In such network deployments, efficient traffic allocation and management is of prominent priority. The increasing congestion conditions of cellular infrastructures have steered extensive research focus towards Heterogeneous Network (HetNet) access solutions. The deployment of dense multiple radio access technology (RAT) networks combined with the enhanced capabilities of mobile devices to maintain concurrent connections through different RATs, add up to the complexity of the traffic allocation problem. Traffic allocation becomes more challenging when using diverse technologies concurrently to serve multiple traffic classes of different Quality of Service (QoS) demands. Towards a viable solution, we have proposed a pricing-based network selection process for heterogeneous networks, running in a distributed manner, which has proved to lead to equilibrium under the developed policies. In this paper, we extend our pricing algorithm by providing a new approach that introduces personalized pricing based on the load pressure that an allocation decision will impose to a RAT. The central system decisions are confined to dynamically select the UE polling rank policy that is presenting the closest potential performance to that of the optimal centralized solution, used as the benchmark ranking. The optimal policy is based on proportional fairness and is used as a reference centralized policy to drive our distributed solutions. We assess the enhanced pricing scheme proposed in this work, and we employ extensive simulations and testbed experimentation to evaluate its performance in terms of efficient bandwidth allocation, price variation, fairness and induced cost to clients served by the HetNet.
Absicherung wertorientierter Unternehmensführung durch Märkte und unternehmensinterne Institutionen (1998)

In Anbetracht der Merkmale der Principal-Agent-Beziehung zwischen Eigentümern und Top-Managern sowie zwischen Managern verschiedener Hierarchiestufen ist zu erwarten, daß Top-Manager nicht automatisch die Ziele der Eigentümer und Manager niedriger Hierarchiestufen nicht per se die Ziele der Manager höherer Hierarchiestufen verfolgen, da sie annahmegemäß eigene Ziele verfolgen. Aus diesem Grund bedarf es Mechanismen, die eine wertorientierte Unternehmensfuhrung sicherstellen.1 Märkte und unternehmensinterne Institutionen sind derartige Mechanismen.2 Die Instrumente, mit denen Märkte und unternehmensinterne Institutionen ihre Koordinationsfunktion erfüllen, sind Anreize und Kontrolle,3 wobei Koordination heißt, menschliches Verhalten in eine bestimmte Richtung zu lenken.4
Economic burden following allogeneic hematopoietic stem cell transplant in patients with diffuse large B-cell lymphoma (2017)

This study describes short-term and long-term healthcare resource utilization (HRU) and costs following an allogeneic hematopoietic stem cell transplant (HSCT) in adult patients with diffuse large B-cell lymphoma (DLBCL) in a real-world setting. Among 101 patients with DLBCL receiving an allogeneic HSCT, HRU and direct healthcare costs for up to three years after the allogeneic HSCT are described. HRU and costs were substantial, with the most intensive HRU and highest healthcare costs observed during the first year after HSCT (38 inpatient days; 68 days with office visits and average healthcare costs of $455,741). Although HRU and costs decreased over time, they remained high even in the third year after HSCT (four inpatient days; 27 days with office visits and average healthcare costs of $72,957). Overall, this study showed that the economic burden following an allogeneic HSCT in DLBCL patients is significant.
Optimization of tasks in cloud computing based on MAX-MIN, MIN-MIN and priority (2018)

Considering the growing use of cloud computing and the need for optimal use of resources in the cloud, and attention to users that pay for services they use based on their pay-as-you-go basis, There should be a quicker way for users to decrease the user's waiting time and task's waiting time. The main purpose of this paper is to provide an optimal algorithm using the advantages of the two traditional Min-Min and Max-Min algorithms. The other point that follow in this algorithm (TOMMP) is the priority of the tasks. There are a lot of scheduling algorithms in the world today, but the priority given to the tasks has been neglected and overlooked in most algorithms. In this algorithm, priority is firstly selected for tasks based on a prioritization algorithm, and then using the median number to decide which one of the Min-Min or Max-Min algorithms is to be used. It should be noted that according to the TOMMP algorithms, its waiting time is lower than comparisons of the compared algorithms and is shown to be better than the comparable algorithms.