gebhart/patrepeval huggingface dataset:
Provider beliefs in effectiveness and recommendations for primary HPV testing in 3 health-care systems (2022)

In 2018, the US Preventive Services Task Force endorsed primary human papillomavirus testing (pHPV) for cervical cancer screening. We aimed to describe providers' beliefs about pHPV testing effectiveness and which screening approach they regularly recommend. We invited providers who performed 10 or more cervical cancer screens in 2019 in 3 healthcare systems that had not adopted pHPV testing: Kaiser Permanente Washington, Mass General Brigham, and Parkland Health; 53.7% (501/933) completed the survey between October and December 2020. Response distributions varied across modalities (P < .001), with cytology alone or cotesting being more often viewed as somewhat or very effective for 30- to 65-year-olds compared with pHPV (cytology alone 94.1%, cotesting 96.1%, pHPV 66.0%). In 21- to 29-year-olds, the pattern was similar (cytology alone 92.2%, 64.7% cotesting, 50.8% pHPV). Most providers were either incorrect or unsure of the guideline-recommended screening interval for pHPV. Educational efforts are needed about the relative effectiveness and recommended use of pHPV to promote guideline-concordant care.
DYNAMIC SURFACE ACTIVITY OF BIOLOGICAL FLUIDS AND OPHTHALMIC SOLUTIONS. (2000)

Third International Conference on the Lacrimal Gland, Tear Film and Dry Eye Syndromes: Basic Science and Clinical Relevance: Maui, Hawaii; November 15-18, 2000: Abstracts
Immunocytochemical colocalization of p16INK4a and Ki‐67 predicts CIN2/3 and AIS/adenocarcinoma (2011)

Dual staining for p16(INK4a)/Ki-67 immunocytochemistry dramatically increased specificity and maintained high-level sensitivity for the diagnosis of CIN2/3 or glandular lesions compared with PCR-based testing for HR-HPV.
Dense Z-pinch at the Nevada terawatt facility (2002)

Summary form only given, as follows. A 2-TW z-pinch (Zebra from LANL: 2 MV, 1.2 MA, 100 ns, 200 kJ, 1.9 ohm) and a 200-MW z-pinch (100 kV, 2 kA, 50 ns) are used to investigate the early-time evolution of a current-driven load. We studied the heating, expansion, and dynamics of wires driven by current prepulses similar to those at SNL-Z in isolated-wire and SNL-Z wire-array geometries. Diagnostics in the X-ray domain include time-resolved imaging, imaging spectroscopy, and X-pinch backlighting. Laser and optical diagnostics include imaging, schlieren, laser-absorption, interferometry, and imaging spectroscopy, obtained with streak cameras and a Nd:glass laser. Other diagnostics X-ray interferometry, polarization X-ray imaging spectroscopy, laser-induced fluorescence, laser polarimetry, and collective Thomson scattering are coming online. 2D and 3D MHD and PIC modelling of Z-pinches has been initiated, initial instability development will be compared with the linear growth rates of m=0 sausage modes, with and without axial sheared flow, axial magnetic field, and the Hall term.
Spontaneous Ignition of Fuel Droplets in Lean Premixtures of Fuel Vapor and Air (2004)

Experiments were carried out on the spontaneous ignition of single fuel droplets in lean premixtures of fuel vapor and air. The n-dodecane droplet was rapidly inserted into high temperature environments and the ignition delay time was obtained from the measurement of OH emissions. Methane and propane were employed as the fuel of premixtures. The waiting time between the introduction of premixture into the hot furnace and the start of experiment of droplet ignition is defined as the residence time. The calculation of chemical reaction of fuel vapor-air mixtures in high temperature during the residence time was also conducted in order to explore the time history of chemical species concentration. In the case of short residence time where the reaction of premixtures does not proceed so much, the ignition delay time is almost the same as that in the air environment, which indicates that the existence of fuel vapor in ambient environments has little effect on the spontaneous ignition behavior. The ignition delay time becomes larger than that in air in the long time residence time, which is due to the decrease in the oxygen concentration in premixtures.
Enhanced field of view multiplexing super-resolution incorporating geometric super-resolution by DLP based sub-pixeling (2022)

In this presentation we show a field of view super-resolution ability while using shifts in time to deal with the diffraction limit as well as the limited density of sampling in space caused due to the stringent size of camera’s pixels/pitch (geometric resolution limit). Using a low-resolution camera, we were able to achieve a high-resolution image by complying with certain conditions that we defined. For that end, we utilized a setup of sub-pixel shifts and grating shifts by time multiplexing, in addition to field of view multiplexing that overcame the diffraction related resolution reduction. The generation of the sub-pixel shifts needed for the operability of the proposed super resolving concept is achieved using DLP device. Improving optical systems resolution is extremely valuable mission in various fields of science and engineering. It helps researchers and industrial companies alike to leap forward the efficiency and ability of their microscopes, telescopes, imaging satellites and aerial photography.
Low Voltage High DC Current AC–DC Conversion (2009)

This chapter contains sections titled: Introduction Present high current rectification technology Hybrid double-group configuration Centre-tapped rectifier option Two-quadrant MLCR rectification Parallel thyristor/MLCR rectification Multicell rectification with PWM control Summary References
STABILIZER (2013)

Researchers and software developers require effective performance evaluation. Researchers must evaluate optimizations or measure overhead. Software developers use automatic performance regression tests to discover when changes improve or degrade performance. The standard methodology is to compare execution times before and after applying changes.
Patavine, a New Arylnaphthalene Lignan Glycoside from Shoot Cultures of Haplophyllum patavinum. (2002)

A new arylnaphthalene lignan glycoside, patavine (1), together with five known lignans, justicidin B (2), diphyllin (3), tuberculatin (4), majidine (5), and arabelline (6) were isolated from shoot cultures of Haplophyllum patavinum. The structure of the new compound was elucidated by extensive one-dimensional (1D) and two-dimensional (2D) NMR experiments and mass spectrometry. The cytotoxicity of compounds 1, and 3-6 against LoVo human colon carcinoma cells was investigated.
INHIBITING ACTION OF LONG ALKYL POLYAMINE(LCMA) ON IRO NCORROSION IN H2S-CONTAINING SULFURIC ACID SOLUTIONS (2009)

Design and synthesis a series of LCMA compounds.The inhibiting action of LCMA in H 2S-containing sulfuric acid solutions has been studied by electrochemical methods.The results showed that LCMA could adsorb in parallel direction and retard anodic and cathodic reactions of iron in H 2S media through negative-catalysis effect.The high inhibiting efficiency of LCMA was closely correlative with the structure of function groups and the length of carbon chain.LCMA with less hydroxyethyl group and longer carbon chain could exhibit more excellent inhibiting effect.The strong inhibiting action of LCMA in low concentration was attributed to the high coverage degree of LCMA molecule,which was resulted from multi-adsorption.
Almighty High Output Type Intelligent Wind Turbine Generator With Tandem Rotors (2007)

Wind is clean, renewable, and homegrown energy source of electric power generation, and has been positively/effectively utilized to cope with the warming global environment. The conventional turbines with large-sized wind rotor generate high output at moderate wind. The power generation of the small-sized wind rotor is low but is suitable for weak wind. That is, the size of the wind rotor must be correctly/appropriately selected in conformity with the wind circumstances. Moreover, the turbines must be equipped with the brake and/or the pitch control mechanisms, in general, to suppress the abnormal rotation and the generated overload at the stronger wind, and to keep good quality of the electric power. To overcome above weak points, the authors have invented the superior wind turbine generator, as shown in Fig. 1. This unit was called “Intelligent Wind Turbine Generator” by the authors, as the rotational speeds of the tandem wind rotors are adjusted pretty well in cooperation with the two armatures of the generator in response to the wind speed. This unit is composed of the large–sized wind rotor, the small-sized wind rotor and the peculiar generator with the inner and the outer armatures without the conventional stator. The front and the rear wind rotors drive the inner and the outer armatures respectively as shown in Fig.1. The rotational torque is counter balanced between the inner and the outer armatures of the generator. The rotational direction and the speed of both wind rotors/armatures are free, and automatically determined in response to the wind circumstance. The superior power generation of the proposed wind turbine generator was verified in the previous report. Continuously, this paper shows the effects of the front wind rotor profiles, the axial distance and the diameter ratio between both wind rotors on the turbine characteristics, in accompanying with the flow conditions around the tandem wind rotors-were experimentally investigated and shows the characteristics of the superior generator.
Author response: Pupal behavior emerges from unstructured muscle activity in response to neuromodulation in Drosophila (2021)

How do we find out how the brain works? One way is to use imaging techniques to visualise an animal’s brain in action as it performs simple behaviours: as the animal moves, parts of its brain light up under the microscope. For laboratory animals like fruit flies, which have relatively small brains, this lets us observe their brain activity right down to the level of individual brain cells. The brain directs movements via collective activity of the body’s muscles. Our ability to track the activity of individual muscles is, however, more limited than our ability to observe single brain cells: even modern imaging technology still cannot monitor the activity of all the muscle cells in an animal’s body as it moves about. Yet this is precisely the information that scientists need to fully understand how the brain generates behaviour. Fruit flies perform specific behaviours at certain stages of their life cycle. When the fly pupa begins to metamorphose into an adult insect, it performs a fixed sequence of movements involving a set number of muscles, which is called the pupal ecdysis sequence. This initial movement sequence and the rest of metamorphosis both occur within the confines of the pupal case, which is a small, hardened shell surrounding the whole animal. Elliott et al. set out to determine if the fruit fly pupa’s ecdysis sequence could be used as a kind of model, to describe a simple behaviour at the level of individual muscles. Imaging experiments used fly pupae that were genetically engineered to produce an activity-dependent fluorescent protein in their muscle cells. Pupal cases were treated with a chemical to make them transparent, allowing easy observation of their visually ‘labelled’ muscles. This yielded a near-complete record of muscle activity during metamorphosis. Initially, individual muscles became active in small groups. The groups then synchronised with each other over the different regions of the pupa’s body to form distinct movements, much as syllables join to form words. This synchronisation was key to progression through metamorphosis and was co-ordinated at each step by specialised nerve cells that produce or respond to specific hormones. These results reveal how the brain might direct muscle activity to produce movement patterns. In the future, Elliott et al. hope to compare data on muscle activity with comprehensive records of brain cell activity, to shed new light on how the brain, muscles, and other factors work together to control behaviour.
Neurodevelopmental Outcomes After Laser Therapy for Twin–Twin Transfusion Syndrome (2011)

A small number (11.1%) of cases of twin-twin transfusion syndrome treated with laser therapy are affected with neurologic impairment that manifests during infancy. A strict follow-up of apparently healthy neonates is warranted.
Random Linear Network Coding for Time Division Duplexing: Energy Analysis (2009)

We study the energy performance of random linear network coding for time division duplexing channels. We assume a packet erasure channel with nodes that cannot transmit and receive information simultaneously. The sender transmits coded data packets back-to-back before stopping to wait for the receiver to acknowledge the number of degrees of freedom, if any, that are required to decode correctly the information. Our analysis shows that, in terms of mean energy consumed, there is an optimal number of coded data packets to send before stopping to listen. This number depends on the energy needed to transmit each coded packet and the acknowledgment (ACK), probabilities of packet and ACK erasure, and the number of degrees of freedom that the receiver requires to decode the data. We show that its energy performance is superior to that of a full-duplex system. We also study the performance of our scheme when the number of coded packets is chosen to minimize the mean time to complete transmission as in. Energy performance under this optimization criterion is found to be close to optimal, thus providing a good trade-off between energy and time required to complete transmissions.
S49 C-reactive protein as a biomarker for improved efficacy of lenzilumab in Covid-19 patients: results from the LIVE-AIR trial (2021)

<h3>Background</h3> The hyperinflammatory cytokine storm (CS) of COVID-19 is mediated by GM-CSF leading to release of downstream inflammatory chemokines, cytokines, and markers of systemic inflammation (C-reactive protein, CRP). The LIVE-AIR study demonstrated that lenzilumab, an anti-GM-CSF monoclonal antibody in patients hospitalized with COVID-19, safely improved the likelihood of achieving the primary endpoint, survival without ventilation (SWOV) by 1.54-fold (HR: 1.54; 95%CI: 1.02–2.32, p=0.0403) compared with placebo. An exploratory analysis in patients with CRP&lt;150 mg/L and age&lt;85 years was conducted to determine lenzilumab efficacy when administered prior to advanced inflammation. <h3>Methods</h3> LIVE-AIR was a phase 3 randomized, double-blind, placebo-controlled trial. Patients with COVID-19 (n=520), &gt;18 years, and ≤94% oxygen saturation on room air and/or requiring supplemental oxygen, but not invasive mechanical ventilation (IMV), were randomized to receive lenzilumab (600 mg, n=261) or placebo (n=259) via three intravenous infusions administered 8 hours apart. Participants were followed through Day 28 following treatment. <h3>Results</h3> Overall, baseline demographics were comparable between treatment groups: male, 64.7%; mean age, 60.5 years; mean BMI, 32.5 kg/m<sup>2</sup>; median CRP, 79 mg/L; CRP was &lt;150 mg/L in 78% of participants. Participants received steroids (93.7%), remdesivir (72.4%), or both (69.1%). Lenzilumab (n=159) improved the likelihood of SWOV by 3.04-fold in participants with CRP&lt;150 mg/L and age&lt;85 years (3.04; 1.68–5.51, nominal p=0.0003) compared with placebo (n=178). Response to lenzilumab was observed in the first through third quartiles of baseline CRP (&lt;41 mg/L, HR:8.33; 41&lt;79 mg/L, HR:1.60; 79&lt;137 mg/L, HR: 2.12; &gt;137 mg/L, HR: 1.17). The incidence of IMV, ECMO, or death was reduced (OR: 0.31; 95%CI: 0.15–0.63, p=0.002) and mortality was improved by 2.22-fold (OR: 2.22; 95%CI: 1.07–4.67, p=0.034). In these participants, lenzilumab decreased CRP as early as Day 2 following treatment, compared with placebo which was further decreased by 38% on Day 28 compared with placebo (24.4±3.4 mg/L vs 39.1±4.9 mg/L). <h3>Conclusion</h3> Lenzilumab significantly improved SWOV in hospitalized, hypoxic participants with COVID-19 pneumonia with the greatest benefits in SWOV and survival in patients with CRP&lt;150 mg/L and age &lt;85 years. Inhibition of GM-CSF, an orchestrator of CS, early in the hyperinflammatory response improved outcomes in COVID-19. NCT04351152
Effect of Anxiety on the Akerfeldt Test (1959)

Acute anxiety episodes do not significantly alter the lag time of the Akerfeldt test, serum ceruloplasmin level, or serum ascorbic acid level in man.
The Murine Coronavirus Hemagglutinin-esterase Receptor-binding Site: A Major Shift in Ligand Specificity through Modest Changes in Architecture (2012)

The hemagglutinin-esterases (HEs), envelope glycoproteins of corona-, toro- and orthomyxoviruses, mediate reversible virion attachment to O-acetylated sialic acids (O-Ac-Sias). They do so through concerted action of distinct receptor-binding ("lectin") and receptor-destroying sialate O-acetylesterase ("esterase") domains. Most HEs target 9-O-acetylated Sias. In one lineage of murine coronaviruses, however, HE esterase substrate and lectin ligand specificity changed dramatically as these viruses evolved to use 4-O-acetylated Sias instead. Here we present the crystal structure of the lectin domain of mouse hepatitis virus (MHV) strain S HE, resolved both in its native state and in complex with a receptor analogue. The data show that the shift from 9-O- to 4-O-Ac-Sia receptor usage primarily entailed a change in ligand binding topology and, surprisingly, only modest changes in receptor-binding site architecture. Our findings illustrate the ease with which viruses can change receptor-binding specificity with potential consequences for host-, organ and/or cell tropism, and for pathogenesis.
Graphene–Gold Metasurface Architectures for Ultrasensitive Plasmonic Biosensing (2015)

Graphene-gold metasurface architectures that can provide significant gains in plasmonic detection sensitivity for trace-amount target analytes are reported. Benefiting from extreme phase singularities of reflected light induced by strong plasmon-mediated energy confinements, the metasurface demonstrates a much-improved sensitivity to molecular bindings nearby and achieves an ultralow detection limit of 1 × 10(-18) m for 7.3 kDa 24-mer single-stranded DNA.
A predictive location model for location-based services (2003)

Location-Based Services (LBSs) utilize information about users' locations through location-aware mobile devices to provide services, such as nearest features of interest, they request. This is a common strategy in LBSs and although it is needed and benefits the users, there are additional benefits when future locations (e.g., locations at later times) are predicted. One major advantage of location prediction is that it provides LBSs with extended resources, mainly time, to improve system reliability which in return increases the users' confidence and the demand for LBSs. However, much of the current location prediction research is focused on generalized location models, where the geographic extent is divided into regular-shape cells. These models are not suitable for certain LBSs whose objective is to compute and present on-road services, because a cell may contain several roads while the computation and delivery of a service may require the exact road on which the user is driving. We propose a new model, called Predictive Location Model (PLM), to predict locations in LBSs with road-level granularities. The premise of PLM is geometrical and topological techniques allowing users to receive timely and desired services.
Extension of the MSIS Thermosphere Model into the middle and lower atmosphere (1991)

The MSIS‐86 empirical model has been revised in the lower thermosphere and extended into the mesosphere and lower atmosphere to provide a single analytic model for calculating temperature and density profiles representative of the climatological average for various geophysical conditions. Tabulations from the Handbook for MAP 16 are the primary guide for the lower atmosphere and are supplemented by historical rocket and incoherent scatter data in the upper mesosphere and lower thermosphere. Low‐order spherical harmonics and Fourier series are used to describe the major variations throughout the atmosphere including latitude, annual, semiannual, and simplified local time and longitude variations. While month to month details cannot be completely represented, lower atmosphere temperature data are fit to an overall standard deviation of 3 K and pressure to 2%. Comparison with rocket and other data indicates that the model represents current knowledge of the climatological average reasonably well, although there is some conflict as to details near the mesopause.
Transmittance and optical constants of Ho films in the 3–1340 eV spectral range (2011)

The optical constants n and k of holmium (Ho) films were obtained in the 3–1340−eV range from transmittance measurements performed at room temperature. Thin films of Ho with various thicknesses were deposited by evaporation in ultra high vacuum conditions and their transmittance was measured in situ. Ho films were deposited onto thin C-film substrates supported on high transmittance grids. Transmittance measurements were used to obtain the extinction coefficient k of Ho films. The refractive index n of Ho was calculated with Kramers−Krönig analysis; in order to do this, k data were extrapolated both on the high and on the low energy parts of the spectrum by using experimental and calculated k values available in the literature. Ho, similar to other lanthanides, has a low-absorption band below the O2,3 edge onset; the lowest absorption was measured at ∼22 eV. Therefore, Ho is a promising material for filters and multilayer coatings in the energy range below the O2,3 edge in which most materials have a large absorption. Good consistency of the data resulted from the application of f and inertial sum rules.
An SEM Study of the Nature of the Electrochemical Deposit in Reversible Electrodeposition Displays (1981)

SEM‐x‐ray spectroscopic studies of display cells based on reversible electrodeposition (RED's) conclusively show that the deposit is composed of elemental silver, regardless of its color (gold, gray, black, red‐brown, etc.) A gold deposit is shown to consist of finely dispersed (colloidal) silver particles, while the black deposit consists of a spongy type of deposit of elemental silver. This fact means that the mechanism of operation of these dispersive displays is due to collective electromagnetic scattering effects of colloidal silver. Confirming evidence that particles form in‐depth contacts is also presented.
Functional inkjet 3D printing system for customized electronics (2017)

We have succeeded in making electronics modules on demand from 3D-CAD data using our prototype functional inkjet 3D printer and are now developing component layer laminating functionality and working on higher throughput. We believe the above system can herald a new era for electronics fabrication.
Dynamic ice contact load model for azimuthing thrusters (2019)

For ships operating in winter conditions, ice loads are important load scenarios for designing azimuthing main propulsion units. One such contact scenario is ice impacting into an azimuthing thruster. In this paper, the formulation of this type of load scenario is presented and existing calculation methods are investigated. A calculation method for dynamic contact load is proposed for ice impact against the main propulsion unit. The basic principle of the proposed load calculation method is an impact of moving bodies combined with dynamic reaction of the structure. The contact load determination is based on the contact pressure–area relationship between an ice block and a steel structure. The dynamic contact problem is solved with a forward difference method. The method is validated with a controlled laboratory-scale test and the test principle is introduced. The dynamic load model is applied to study the effect of dynamics on the response load level.