gebhart/patrepeval huggingface dataset:
Stable Cationic Capillary Coating with Successive Multiple Ionic Polymer Layers for Capillary Electrophoresis (1998)

A coated capillary modified with a cationic polymer was developed by using a novel coating procedure, successive multiple ionic-polymer (SMIL) coating. The SMIL coating was achieved by first attaching the cationic polymer to the capillary inner wall, and then the anionic polymer to the cationic polymer layer, and finally the cationic polymer to the anionic polymer layer. The stability of Polybrene (PB)-modified capillary made by SMIL coating was remarkably improved in comparison with a conventional PB-modified capillary. It endured during 600 replicate analyses and also showed strong stability against 1 M NaOH and 0.1 M HCl. The relative standard deviation of the run-to-run, day-to-day, and capillary-to-capillary coating was all below 1%, and good reproducibilities were obtained. The PB-modified capillary made by SMIL coating was applied to the basic protein analyses. It gave good performances for the protein analyses even when the pH of the electrolyte was near the isoelectric point (pI) of the protein. In addition, 0.1 M NaOH rinse prior to the sample injection allowed the reproducible analysis of a highly adsorptive sample such as plasma because the adsorbed sample could be flushed out of the capillary. Besides protein analyses, an efficient analysis of the cationic drugs by capillary electrophoresis/mass spectrometry (CE/MS) was also possible.
Synthesis of New Glucosylated Porphyrins Bearing an α‐d‐Linkage (2006)

International audience
Gene‐Expression Patterns in Whole Blood Identify Subjects at Risk for Recurrent Tuberculosis (2007)

A simple test based on gene-expression patterns may be used as a biomarker of cure while identifying patients who are at risk for relapse. This would facilitate the introduction of new tuberculosis drugs.
High data rate UWB performance with reduced implementation complexity (2005)

The bit error rate (BER) performance of the imperfect digital matched filter (IDMF) receiver in a typical multiuser scenario assuming LOS conditions for the terminals is investigated. Due to the extremely high processing requirements of the digital matched filter, it is assumed that for an implementation the number of bits as well as the number of filter coefficients has to be as low as possible introducing implementation loss. Furthermore imperfect channel estimation is taken into account. The resulting BER performance of the IDMF receiver is compared to the BER performance of the ideal matched filter receiver. Additionally the BER performance of a coded IDMF receiver, which applies sophisticated turbo forward error correction coding, is investigated. The results show that the IDMF receiver can reach the uncoded target BER of 10/sup -2/ in the environment investigated and that this uncoded BER corresponds to a coded BER of less than 10/sup -6/. For the IDMF receiver the required E/sub b//N/sub 0/ ratio to achieve the target BER strongly depends on the number of filter coefficients.
ChemInform Abstract: RING‐STRAINED CARBODIPHOSPHORANES (1980)

Abstract Ausgehend von Methylen‐bis‐[diphenylphosphin] (I) werden durch Quatemierung mit den Dihalogenalkanen (II) die ditert.
Measurements of discharge coefficients in film cooling (1998)

Measurements of discharge coefficients for several film cooling configurations having hole length-to-diameter ratios of 2.3, 4.6, 6.6, and 7.0 are presented. Recently, it was documented that the velocity distributions over the hole exit plane vary significantly with changes in hole length-to-diameter ratio. This paper documents the effects of such variations on coolant discharge coefficients. Due to the short holes, injection in engines is with a substantial amount of coolant departing the upstream portions of the hole exit plane. This results in a higher rate of momentum exchange with the free stream at that location than for longer holes, which permits more uniform exit flows. Discharge coefficient measurements are discussed in terms of this distribution of velocity. This paper also documents the effects of the hole supply plenum geometry on discharge coefficients. When the coolant flow is delivered to the holes with significant momentum either in the direction of the free stream or opposite to that direction, significant changes in discharge coefficient values are observed.
Data-Consistent Non-Cartesian Deep Subspace Learning for Efficient Dynamic MR Image Reconstruction (2022)

Non-Cartesian sampling with subspace-constrained image reconstruction is a popular approach to dynamic MRI, but slow iterative reconstruction limits its clinical application. Data-consistent (DC) deep learning can accelerate reconstruction with good image quality, but has not been formulated for non-Cartesian subspace imaging. In this study, we propose a DC non-Cartesian deep subspace learning framework for fast, accurate dynamic MR image reconstruction. Four novel DC formulations are developed and evaluated: two gradient decent approaches, a directly solved approach, and a conjugate gradient approach. We applied a U-Net model with and without DC layers to reconstruct T1-weighted images for cardiac MR Multitasking (an advanced multidimensional imaging method), comparing our results to the iteratively reconstructed reference. Experimental results show that the proposed framework significantly improves reconstruction accuracy over the U-Net model without DC, while significantly accelerating the reconstruction over conventional iterative reconstruction.
Preparation and thermal characterization of oxalic acid dihydrate/bentonite composite as shape-stabilized phase change materials for thermal energy storage (2017)

Oxalic acid dihydrate (OAD) which has very high initial phase transition enthalpy is a promising phase change material (PCM). In this paper, shape-stabilized composite PCMs composed of OAD and bentonite were prepared by a facile blending method to overcome the problem of leakage. FT-IR results indicated the interactions between OAD and bentonite, such as the capillary force and the hydrogen bonding, resulting in the confined crystallization process. As a result, the OAD was confined to be amorphous. The thermogravimetric analysis and scanning electron microscope results showed that sample had the best coating effect when the amount of bentonite was 17.7%. The differential scanning calorimetry analyses demonstrated that a decrease in the OAD content was accompanied by a continuous decrease in the melting point and phase change enthalpy of the composites.
Requirement of basement membrane for the suppression of programmed cell death in mammary epithelium (1996)

Apoptosis is an active mechanism of cell death required for normal tissue homeostasis. Cells require survival signals to avoid the engagement of apoptosis. In the mammary gland, secretory epithelial cells are removed by apoptosis during involution. This cell loss coincides with matrix metalloproteinase activation and basement membrane degradation. In this paper we describe studies that confer a new role for basement membrane in the regulation of cell phenotype. We demonstrate that the first passage epithelial cells isolated from pregnant mouse mammary gland die by apoptosis in culture, but that cell death is suppressed by basement membrane. The correct type of extracellular matrix was required, since only a basement membrane, not plastic or a collagen I matrix, lowered the rate of apoptosis. Attachment to a matrix per se was not sufficient for survival, since apoptotic cells were observed when still attached to a collagen I substratum. Experiments with individually isolated cells confirmed the requirement of basement membrane for survival, and demonstrated that survival is enhanced by cell-cell contact. A function-blocking anti-beta1 integrin antibody doubled the rate of apoptosis in single cells cultured with basement membrane, indicating that integrin-mediated signals contributed to survival. We examined the cell death-associated genes bcl-2 and bax in mammary epithelia, and found that although the expression of Bcl-2 did not correlate with cell survival, increased levels of Bax were associated with apoptosis. We propose that basement membrane provides a survival stimulus for epithelial cells in vivo, and that loss of interaction with this type of matrix acts as a control point for cell deletions that occur at specific times during development, such as in mammary gland involution.
PONDER policy implementation and validation in a CIM and differentiated services framework (2004)

Policies are often used to define management strategies for networks, storage services or applications. Validation determines whether the policy implementation is feasible for the specific environment to which it applies and requires checking that the policy is consistent with the functional or resource constraints within the target environment. For example, do the policies assume functionality or specific operations which do not exist in target routers, or bandwidth in excess of the capacity of data links? Where possible, static checking should be done prior to policy deployment in order to detect invalid policies at design time, but there are some policies, related to resource allocation, that depend on the current state of the system, and require policy constraints that must be checked dynamically at execution time. We show how PONDER policies can be implemented and validated for differentiated services (DiffServ) by using CIM (Common Information Model) as the modelling framework for network resources, as this is device independent. We describe a CIM DiffServ-metrics sub-model extension of the CIM Network sub-model which represents DiffServ traffic statistics and a Linux driver which translates CIM classes and variables to Linux traffic control classes and variables respectively.
Formation of a porous cerium oxide membrane by anodization (2011)

A two-step synthetic process is reported to fabricate porous ceria membranes by anodization of cerium metal foils with subsequent calcination. "Ribbon-like" structures were found to form the backbones of these porous frameworks. The hydrophobic nature of these membranes was revealed by water contact angle measurements.
Immediate Outcome Indicators in Perioperative Care: A Controlled Intervention Study on Quality Improvement in Hospitals in Tanzania (2013)

Quality assurance programs based on immediate outcome indicators can be effective if embedded in Continuous Quality Improvement. Nevertheless, final outcome indicators cannot be neglected.
Remarkable Catalytic Property of Nanoporous Gold on Activation of Diborons for Direct Diboration of Alkynes (2013)

A novel catalytic property of nanoporous gold for activation of bis(pinacolato)diboron has been reported that allows the direct diboration of alkynes to proceed sufficiently in a heterogeneous process. The experimental results revealed that the nanoporous gold catalyst is able to cleave the B-B bond of bis(pinacolato)diboron without using any additives.
RIPK1-RIPK3-MLKL-dependent necrosis promotes the aging of mouse male reproductive system (2017)

A pair of kinases, RIPK1 and RIPK3, as well as the RIPK3 substrate MLKL cause a form of programmed necrotic cell death in mammals termed necroptosis. We report here that male reproductive organs of both <i>Ripk</i>3- and <i>Mlkl</i>-knockout mice retain 'youthful' morphology and function into advanced age, while those of age-matched wild-type mice deteriorate. The RIPK3 phosphorylation of MLKL, the activation marker of necroptosis, is detected in spermatogonial stem cells in the testes of old but not in young wild-type mice. When the testes of young wild-type mice are given a local necroptotic stimulus, their reproductive organs showed accelerated aging. Feeding of wild-type mice with an RIPK1 inhibitor prior to the normal onset of age-related changes in their reproductive organs blocked the appearance of signs of aging. Thus, necroptosis in testes promotes the aging-associated deterioration of the male reproductive system in mice.
A CASE WITH PAROXYSMAL VENTRICULAR FIBRILLATION, SIGNIFICANT U WAVE AND NORMOKALEMIA (1970)

著着らは,血清カリウム値が正常範囲にあるのにもかかわらず,心電図に著明なU波を示し, 11年間も一過性心室細動発作をくり返していた症例を経験した.この発作は,精神的因子で誘発されやすい傾向があり,また内分泌因子とも何らかの関係がありそうに思えた.しかし明らかな,器質的心疾患は証明できなかつた. 2人の姉たちにも,心電図上同様のU波が見られるが,発作は経験していない.心電図波形は,血清力リウム濃度よりは,むしろ心筋細胞内カリウム濃度に関係することから,本症例にみられた心電図所見は,心筋細胞内外カリウム比の異常を反映したものと推定された.カリウム薬の投与で,発作は出現しなくなつた.
Phosphorylation of octamer-binding transcriptional factor may be correlated with H2B histone gene repression during 12-O-tetradecanoylphorbol 13-acetate-dependent differentiation of HL-60 cells (2005)

To gain insight on the role of transacting factors in the regulatory mechanism of H2B histone gene expression during the differentiation of HL-60 cells by 12-O-tetradecanoylphorbol 13-acetate (TPA), the binding pattern of nuclear proteins to various elements in the human H2B histone gene upstream region have been investigated with DNase I footprinting and DNA mobility shift assay. The level of H2B histone mRNA rapidly reduced at 24 h in TPA-treated HL-60 cells. The H2B histone mRNA was repressed in proportion to the concentration of TPA. In DNase I footprinting analysis, one nuclear factor (octamer-binding transcription factor, OTF) bound at -42 bp (octamer motif), before and after TPA-induced differentiation of HL-60 cells. One DNA-protein complex (OTF) was formed by DNA mobility shift assay when octamer element was incubated with nuclear extract of undifferentiated HL-60 cells. In DNA mobilith shift assay, OTF vanished, and phosphorylated OTF (p-OTF) newly appeared during TPA-induced differentiation. p-OTF was not detected after pretreatment of the protein kinase C inhibitor, staurosporin, but was not changed after CHX treatment. TPA-induced repression of H2B histone mRNA was also restored after pretreatment of staurosporin. These results suggest that OTF is phosphorylated by protein kinase C during TPA-induced differentiation of HL-60 and the transcriptional repression of the H2B histone gene may be mediated by protein kinase C-dependent phosphorylation of OTF.
A pyramidal silicon probe with an extremely high throughput and resolution for optical near field technology (2002)

Summary form only given. For improvement in the performances of spatially resolved spectroscopy, optical data storage, and so on, we demonstrate here an extremely high throughput and resolution capability of a pyramidal silicon probe for near-field optical microscopy. Since the high refractive index of the silicon (n=3.67, @ /spl lambda/=830 nm) leads to a short effective wavelength inside the probe, which results in high throughput and spatial resolution compared to conventional fiber probes.
[Molecular diagnosis of influenza A(H1N1) 2009 virus and other respiratory viruses during the first pandemic wave in Cuba]. (2013)

the molecular diagnosis algorithm proved to be sensitive, specific and effective to assure the systematic virological surveillance in our country during the pandemic phase.
High Dimensional Principal Component Scores and Data Visualization (2012)

Principal component analysis is a useful dimension reduction and data visualization method. However, in high dimension, low sample size asymptotic contexts, where the sample size is fixed and the dimension goes to infinity,a paradox has arisen. In particular, despite the useful real data insights commonly obtained from principal component score visualization, these scores are not consistent even when the sample eigen-vectors are consistent. This paradox is resolved by asymptotic study of the ratio between the sample and population principal component scores. In particular, it is seen that this proportion converges to a non-degenerate random variable. The realization is the same for each data point, i.e. there is a common random rescaling, which appears for each eigen-direction. This then gives inconsistent axis labels for the standard scores plot, yet the relative positions of the points (typically the main visual content) are consistent. This paradox disappears when the sample size goes to infinity.
Physical Rehabilitation of the Injured Athlete. 3rd ed. (2005)

1 University of Pittsburgh School of Health and Rehabilitation Sciences Pittsburgh, Pennsylvania 2 University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania
ChemInform Abstract: Pterocarposide, an Isoaurone C‐Glucoside from Pterocarpus marsupium. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Quality of Experience Optimization Technology (Quality API) (2015)

A collaboration between NTT and Dwango Co., Ltd., a video distribution company, is expected to improve the quality of experience (QoE) for customers.
Motion Estimation by Quadtree Pruning and Merging (2006)

In this paper we propose a rate-distortion optimized motion estimation algorithm that is built upon a quadtree structure. Each node of the quadtree represents a block in the current frame together with its motion vector, and the block size decreases from the root to the leaves. In the first step, the quadtree is pruned according to a rate-distortion criterion in order to obtain blocks of variable sizes. A further rate rebate can be achieved by merging those leaf nodes of the quadtree that can be efficiently represented by the same motion vector. The proposed merging scheme provides a reduction of up to 50% of the rate spent for the motion model with respect to the case that performs pruning only
SIPES March Luncheon Meeting Selected Topics in Seismic Dispersion (2012)

This presentation is a survey of selected frequency-dependent phenomena routinely encountered in reflection seismic data. At first impression the topic seems self-evident; everything is frequency dependent. However, much of classical seismology and wave theory is non-dispersive — the theory of P and S waves, Rayleigh waves in a half-space, geometric spreading, reflection and transmission coefficients, head waves, etc. The convolutional reflection models we use to model thick and thin bed thin response, as well as most inversion techniques, do not include dispersion phenomena. And yet when we look at real data, strong dispersion abounds. The classical meaning of the word dispersion is frequency-dependent velocity. We take a more general definition that includes not just wave speed, but also interference, attenuation, anisotropy, reflection characteristics and other aspects of seismic waves that show frequency-dependence. We will examine the interpretive challenges presented by the reality of dispersion using modern, real data examples.
Effects of dichloroacetate and bicarbonate on haemodynamic parameters in healthy volunteers (1991)

1. It has been shown that sodium bicarbonate has no effect or could even be detrimental in various forms of metabolic acidosis. Dichloroacetate, a stimulator of the pyruvate dehydrogenase complex, might offer an alternative treatment. The present study therefore examines the metabolic and haemodynamic effects of dichloroacetate and sodium bicarbonate in healthy volunteers. 2. On 2 different days, sodium dichloroacetate (50 mg/kg body weight) or sodium bicarbonate (1.5 mmol/kg body weight) was given intravenously as a single bolus in 10 healthy volunteers. Haemodynamic parameters were measured using a microprocessor-controlled system. Measurements were performed before and 30 and 60 min after infusion. 3. After administration of dichloroacetate, cardiac index increased from 2.3 +/- 0.03 to 2.7 +/- 0.1 1 min-1 m-2 (P less than 0.05), peripheral vascular resistance decreased from 266 +/- 9.7 to 240 +/- 1.7 kPa s l-1 (2662 +/- 97 to 2398 +/- 169 dyn s cm-5, P less than 0.05), oxygen availability increased from 442 +/- 16 to 535 +/- 30 ml min-1 m-2 (P less than 0.05) and serum lactate concentration fell from 1.4 +/- 0.14 to 0.6 +/- 0.1 mmol/l (P less than 0.05). With infusion of sodium bicarbonate there were no significant effects on any of these variables. 4. Our results show that dichloroacetate administered intravenously reduces the serum lactate concentration. The main effects of dichloroacetate itself are on the haemodynamic variables. Dichloroacetate increases cardiac index and oxygen availability and decreases peripheral vascular resistance, whereas sodium bicarbonate has no effect on haemodynamic or metabolic parameters. These data give some further insights in the actions of dichloroacetate and support the use of dichloroacetate as alternative therapy in various forms of metabolic acidosis.
Solidification and Melting – Asymmetries and Consequences (2006)

Solidification and melting are phase transitions from the liquid to solid state or vice versa and are thus often assumed to be similar processes with only opposite direction. However, they can be fundamentally different, i.e. asymmetric, in aspects of both thermodynamics and kinetics. It is known that superheat in the solid is difficult to obtain, unlike supercooling in the liquid. This is often attributed to the fact that nucleation in the liquid can occur (homogeneously or heterogeneously) in the bulk, in the solid it will occur at outer or inner surfaces of the crystal. A further asymmetry is evident as the growing phase is a phase with fast diffusion kinetics in the case of melting, with slow diffusion kinetics in the case of solidification. Two types of experiments (solutal melting and melting/resolidification in a temperature gradient) are presented that allow an evaluation and quantification of the consequences of these asymmetries.
Chronic Interstitial Nephropathy in Mice Induced by Psychosocial Stress: Potentiation by Caffeine (1983)

Chronic psychosocial stress in male mice produces chronic interstitial nephropathy not explained by renal vascular disease or urinary infection. Four groups of male CBA mice were studied. Group 1 and group 2 were placed in Henry-Stephens complex population cages for 5 months. Group 2 had caffeine, 800 micrograms/ml, added to their drinking water. Control groups 3 and 4 were unstressed, but group 4 had 800 micrograms/ml of caffeine added to their water. Stressed animals developed chronic interstitial nephropathy which was more severe in animals drinking caffeinated water. In addition, the percent of cortex involved in interstitial fibrosis was higher in group 2, 18.0 +/- 1.4, than in group 1, 15.2 +/- 2.3 (p less than 0.05). Both groups had more fibrosis than unstressed animals (p less than 0.01). Blood urea nitrogen was more elevated in group 2, 47 +/- 13 mg/dl, than in group 1, 29 +/- 17 mg/dl (p less than 0.05). Again both values exceeded those in unstressed animals (p less than 0.01). It is concluded that prolonged environmental stress can lead to the renal morphologic changes of chronic interstitial nephritis. Both renal pathology and function are worse when there is concurrent high caffeine intake. The relevance of this model to human disease related to analgesic use or with affective illness requires further study.
Stability of one dimensional steady state domain wall motion (1989)

The magnetization configuration and stability limits of one-dimensional domain walls with orthorhombic anisotropy and an applied field normal to the wall are studied in steady-state motion. The calculations are carried out directly on the directional sphere in the lossless instance. The Walker breakdown mechanism, in which the motion breaks down simultaneously along the entire wall profile, is replaced by three distinct mechanisms: domain instability in which the wall motion breaks down asymptotically far from the center of the wall, and two types of domain-wall instability in which the breakdown occurs within the wall. The two types of domain-wall instability are distinct in that only one is identified by Jacobi equation analysis.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>