gebhart/patrepeval huggingface dataset:
Interview with Paul H. Emmett (1978)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTInterview with Paul H. EmmettBurtron H. Davis Cite this: J. Chem. Educ. 1978, 55, 4, 248Publication Date (Print):April 1, 1978Publication History Received3 August 2009Published online1 April 1978Published inissue 1 April 1978https://doi.org/10.1021/ed055p248RIGHTS & PERMISSIONSArticle Views56Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (4 MB) Get e-Alerts Get e-Alerts
A Wound Healing Model Using Healing‐impaired Diabetic Mice (1992)

A quantitative histological approach was employed to evaluate the effects of basic fibroblast growth factor (bFGF) in healing-impaired diabetic mice. The dorsal areas of female mutant diabetic mice, C57BL KsJ db/db (Jackson Lab.), were given two 6 mm-size full thickness wounds with a punch biopsy instrument. After application of bFGF, the wounds were left open. 8 days after wounding, the mice were sacrificed, and histological sections were evaluated using several histological parameters, such as the degree of wound closure, granulation tissue thickness, matrix density, and capillary numbers. Application of 5 micrograms of bFGF for 5 days induced significant responses by all of these dermal parameters when compared to those of non-treated db/db mice (p < 0.001). A minimum of 0.5 micrograms bFGF per day was required for a significant effect. Time-course experiments indicated that the granulation response in bFGF-treated mice peaked between 8 and 12 days and decreased after 12 days, while matrix density continued to increase until the 18th day.
Inhibition of the Enhancement of Infection of Human Immunodeficiency Virus by Semen-Derived Enhancer of Virus Infection Using Amyloid-Targeting Polymeric Nanoparticles (2015)

The semen-derived enhancer of virus infection (SEVI) is a natural amyloid material that has been shown to substantially increase viral attachment and infectivity of HIV in cells. We previously reported that synthetic monomeric and oligomeric amyloid-targeting molecules could form protein-resistive coatings on SEVI and inhibit SEVI- and semen-mediated enhancement of HIV infectivity. While oligomeric amyloid-binding compounds showed substantial improvement in apparent binding to SEVI compared to monomeric compounds, we observed only a modest correlation between apparent binding to SEVI and activity for reducing SEVI-mediated HIV infection. Here, we synthesized amyloid-binding polyacrylate-based polymers and polymeric nanoparticles of comparable size to HIV virus particles (∼150 nm) to assess the effect of sterics on the inhibition of SEVI-mediated enhancement of HIV infectivity. We show that these polymeric materials exhibit excellent capability to reduce SEVI-mediated enhancement of HIV infection, with the nanoparticles exhibiting the greatest activity (IC50 value of ∼4 μg/mL, or 59 nM based on polymer) of any SEVI-neutralizing agent reported to date. The results support that the improved activity of these nanomaterials is likely due to their increased size (diameters = 80-200 nm) compared to amyloid-targeting small molecules and that steric interactions may play as important a role as binding affinity in inhibiting viral infection mediated by SEVI amyloids. In contrast to the previously reported SEVI-neutralizing, amyloid-targeting molecules (which required concentrations at least 100-fold above the Kd to observe activity), the approximate 1:1 ratio of apparent Kd to IC50 for activity of these polymeric materials suggests the majority of polymer molecules that are bound to SEVI contribute to the inhibition of HIV infectivity enhanced by SEVI. Such size-related effects on physical inhibition of protein-protein interactions may open further opportunities for the use of targeted nanomaterials in disease intervention.
Studies on Egyptian sesame seeds (Sesamum indicum L.) and its products. 3. Effect of roasting process on gross chemical composition, functional properties, antioxidative components and some minerals of defatted sesame seeds meal (Sesamum indicum L.). (2013)

Sesame seed (Sesamum indicum L.) is one of the world's most important and oldest oilseed crops with a high level content of nutrients and antioxidants known to human health. Sesame seeds are usually roasted prior to expelling oil. The changes of chemical composition, functional properties and antioxidant activity of defatted sesame seeds meal (DSSM) before and after roasting were investigated. The DSSM samples contained 1.72-2.76% moisture, 2.20-3.58% crude oil, 45.05-55.20% crude proteins, 9.60-20.51% carbohydrate (by difference), 22.49-24.48% crude fiber and 5.11-6.94% ash. A significant reduction was observed in the mineral composition with roasting treatment when compared with the raw sample. Functional properties (WAC and OAC) of DSSM were also determined. The antioxidant factors responsible for the stability of DSSM are highly affected by the roasting process. The total phenolics content in the methanolic extract from DSSM and the antioxidant activity of DSSM also increased with roasting.
Vision-controlled robotic tracking and acquisition (2002)

A vision-controlled robot conveyor tracking system is presented here. The vision system utilizes a constant in-time sensing field. In its normal mode of operation, this system takes a picture, analyses the image, recognises the object, extracts position information from it. Utilising this information along with the velocity information from the conveyor belt, the robot maneuvers to track and grasp the recognised object.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Treatment Review: Non‐Steroid Anti‐Inflammatory Drugs in the Treatment and Long‐Term Prevention of Migraine Attacks (1988)

SYNOPSIS After reviewing the pathophysiological features suggesting a role of prostaglandins in migraine, we have analyzed the literature concerning double‐blind trials of anti‐inflammatory drugs versus placebo or reference compounds in the acute and long‐term preventive treatment of migraine. For both of these indications, in the majority of double‐blind trials NSAID's have been found to be superior to placebo and equivalent to reference drugs. Certain points remain to be defined including, in particular, the following: • acceptability in the long‐term or by frequent repeated administrations, • efficacy according to different types or factors inducing migraine. More extensive trials are therefore indicated.
Determination of Fe, Cu, Zn, Se and As in Biological Samples Using ICP-Ion Trap Mass Spectrometer (2006)

イオントラップ型質量分析計を採用している誘導結合プラズマ三次元四重極質量分析計を用いて，生体試料中のFe，Cu，Zn，As及びSeのうち存在量の最も大きい同位体に関するスペクトル干渉を低減し，生体試料中のFe，Cu，Zn，As及びSeの定量を行った．三次元四重極質量分析計（3DQMS）の装置条件とFNF（filtered noise field）を最適化することで，解離エネルギーが低い56Fe+に対する40Ar16O+，63Cu+に対する40Ar23Na+，75As+に対する40Ar35Cl+及び80Se+に対する40Ar2+のスペクトル干渉は低減できた．また，解離エネルギーが比較的高い56Fe+に対する40Ca16O+，64Zn+に対する32S2+及び80Se+に対する79Br1H+のスペクトル干渉はFNFに加えCID（collision induced dissociation）機能を最適化することで，低減できた．CIDの最適条件はそれぞれ0 V，500 msであった．装置条件，FNF及びCIDの最適条件の下で，生体標準物質中のFe，Cu，Zn，As及びSeの定量を行った結果，誤差範囲内で保証値と一致した．また，実試料としてヒト血清を定量した．
Intestinal Innate Immunity toCampylobacter jejuniResults in Induction of Bactericidal Human Beta-Defensins 2 and 3 (2005)

Campylobacter jejuni is the most prevalent cause of bacterial diarrhea worldwide. Despite the serious health problems caused by this bacterium, human innate immune responses to C. jejuni infection remain poorly defined. Human beta-defensins, a family of epithelial antimicrobial peptides, are a major component of host innate defense at the gastrointestinal mucosal surface. In this study, the effect of two different C. jejuni wild-type strains on human intestinal epithelial innate responses was investigated. Up-regulation of beta-defensin gene and peptide expression during infection was observed and recombinant beta-defensins were shown to have a direct bactericidal effect against C. jejuni through disruption of cell wall integrity. Further studies using an isogenic capsule-deficient mutant showed that, surprisingly, the absence of the bacterial polysaccharide capsule did not change the innate immune responses induced by C. jejuni or the ability of C. jejuni to survive exposure to recombinant beta-defensins. This study suggests a major role for this family of antimicrobial peptides in the innate immune defense against this human pathogen.
Field Experimenting with Semantic Web Tools in a Virtual Organization (2002)

This chapter contains sections titled: Introduction The EnerSearch Industrial Research Consortium as a Virtual Organization Why Might Semantic Web Methods Help? Design Considerations of Semantic Web Field Experiments Experimental Set-up in a Virtual Organization Technical and System Aspects of Semantic Web Experiments Ontology-based Information Retrieval: What Does It Look Like? Some Lessons Learned
Contrast‐enhanced ultrasonography for the differential diagnosis of pleomorphic adenomas and Warthin tumors in salivary glands (2021)

3b.
STAT3 promotes motor neuron differentiation by collaborating with motor neuron-specific LIM complex (2013)

The motor neuron (MN)-hexamer complex consisting of LIM homeobox 3, Islet-1, and nuclear LIM interactor is a key determinant of motor neuron specification and differentiation. To gain insights into the transcriptional network in motor neuron development, we performed a genome-wide ChIP-sequencing analysis and found that the MN-hexamer directly regulates a wide array of motor neuron genes by binding to the HxRE (hexamer response element) shared among the target genes. Interestingly, STAT3-binding motif is highly enriched in the MN-hexamer-bound peaks in addition to the HxRE. We also found that a transcriptionally active form of STAT3 is expressed in embryonic motor neurons and that STAT3 associates with the MN-hexamer, enhancing the transcriptional activity of the MN-hexamer in an upstream signal-dependent manner. Correspondingly, STAT3 was needed for motor neuron differentiation in the developing spinal cord. Together, our studies uncover crucial gene regulatory mechanisms that couple MN-hexamer and STAT-activating extracellular signals to promote motor neuron differentiation in vertebrate spinal cord.
Nanobubbles for enhanced ultrasound imaging of tumors (2012)

The fabrication and initial applications of nanobubbles (NBs) have shown promising results in recent years. A small particle size is a basic requirement for ultrasound contrast-enhanced agents that penetrate tumor blood vessel pores to allow for targeted imaging and therapy. However, the nanoscale size of the particles used has the disadvantage of weakening the imaging ability of clinical diagnostic ultrasound. In this work, we fabricated a lipid NBs contrast-enhanced ultrasound agent and evaluated its passive targeting ability in vivo. The results showed that the NBs were small (436.8 ± 5.7 nm), and in vitro ultrasound imaging suggested that the ultrasonic imaging ability is comparable to that of microbubbles (MBs). In vivo experiments confirmed the ability of NBs to passively target tumor tissues. The NBs remained in the tumor area for a longer period because they exhibited enhanced permeability and retention. Direct evidence was obtained by direct observation of red fluorescence-dyed NBs in tumor tissue using confocal laser scanning microscopy. We have demonstrated the ability to fabricate NBs that can be used for the in vivo contrast-enhanced imaging of tumor tissue and that have potential for drug/gene delivery.
Nanosession: Spin Dynamics (2012)

This chapter presents a micromagnetic study on domain walls (DW) dynamics in ferromagnetic nanotubes. In analogy to the well-established charge currents, a pure spin current is the directed flow of spin angular momentum. Further understanding of complex materials, such as agnetic alloys and metallic multilayers or multiferroics, requires an experimental technique that allows testing the electronic and magnetic properties of a targeted material element-selectively on femtosecond time scales and with nanometer lateral resolution. The chapter describes the ultrafast inverse Faraday effect (IFE) via the stimulated Raman scattering process by the solution of the time-dependent Schrödinger equation. The spin relaxation in non-magnetic metallic thin films is an important effect in spintronics, especially due to the decreasing dimensionality of magnetic multilayers. Using the Korringa-Kohn-Rostoker Green function method, the Elliott-Yafet parameter as well as the spin relaxation time by adding adatom impurities are calculated for 5d transition-metal ultrathin films. Controlled Vocabulary Terms Faraday effect; ferromagnetism; nanotubes; spin dynamics; thin films; transition metals
Evaluating generalized predictive control for a brushless DC drive (1998)

This paper proposes a new control approach for a brushless DC motor drive using the generalized predictive control (GPC) algorithm. Based on the same least-squares framework as in the controller design, we further develop the method to design an observer. The GPC algorithm uses the receding horizon approach whereby the control signals are determined by minimizing a quadratic cost function. Our study shows that the rise time and settling time of the servo system have an approximate linear relationship with the prediction horizon. Thus, it is used to tune the controller of the drive. Moreover, the control weighting factor can be used to smooth the controller output. The proposed algorithm has been implemented using a digital signal processor (DSP) and tested in real time with a prototype system. The performance and robustness of the algorithms have been evaluated both in simulation and experiment. The results show that the drive performs reasonably well despite load changes and step changes in the position setpoint. Furthermore, it is fairly robust against motor parameters change.
La biopsie des tumeurs de l’encéphale par stéréotaxie assistée par tomodensimétrie : mise au point d’un nouveau cadre et premières applications cliniques chez le chien (1999)

Le diagnostic précis des lésions de l’encéphale ne peut être obtenu qu’après examen histopathologique d’une biopsie. Nous décrivons la conception d’un prototype permettant la réalisation d’une biopsie par stéréotaxie assistée par tomodensitométrie dont le but est d’obtenir le prélèvement de cibles d’un diamètre supérieur à 1 cm chez le chien. La précision de la procédure fut tout d’abord mesurée en injectant 1 ml d’un produit pâteux radio-opaque en une cible préalablement déterminée (coordonnées xl yl, zl) au sein de 10 cerveaux frais de chiens. Un nouveau scanner permettait de déterminer le centre de la masse ainsi créée et de calculer la différence entre les coordonnées de la cible et de la biopsie réelle selon les axes X, Y et Z. La technique fut alors appliquée chez 8 chiens présentant des tumeurs cérébrales. La procédure a démontré sa grande précision dans les deux essais. La précision fut calculée à 2,9 mm. La biopsie fut diagnostiquée dans les 8 cas et deux complications furent observées. La biopsie stéréotaxique assistée par tomodensitométrie est une technique rapide, aisée et reproductible, indiquée en présence de toute lésion cérébrale mal caractérisée par la seule imagerie chez le chien.
Development of large-size CPU package structure using embedded thin film capacitor substrate (2017)

This paper reports on a large-size CPU package for UNIX servers which employs embedded thin film capacitor layers. The substrate of this package has two thin film capacitor layers in the surface of the core layer, which has a capacitance of 25 uF in total. In order to adopt this package substrate, we confirmed the effect of the thin film capacitor layers on the package assembly process. We actually measured mechanical characteristics and the coefficient of thermal expansion (CTE), and confirmed that we can use it like conventional package substrates. This package has passed the preprocessing and subsequent environmental test on JEDEC Level 4, and we think that a high-quality package has been developed this time.
Filters and parameter estimation for a partially observable system subject to random failure with continuous-range observations (2004)

We consider a failure-prone system operating in continuous time. Condition monitoring is conducted at discrete time epochs. The state of the system is assumed to evolve as a continuous-time Markov process with a finite state space. The observation process with continuous-range values is stochastically related to the state process, which, except for the failure state, is unobservable. Combining the failure information and the condition monitoring information, we derive a general recursive filter, and, as special cases, we obtain recursive formulae for the state estimation and other quantities of interest. Updated parameter estimates are obtained using the expectation-maximization (EM) algorithm. Some practical prediction problems are discussed and finally an illustrative example is given using a real dataset.
Research Note: The Effect of Tamoxifen on Semen Fertilization Capacity in White Leghorn Male Chicks (1990)

Tamoxifen (TAM) is an antiestrogen that advances sexual puberty in cockerels, turkey toms, and Muscovy drakes. The effect of TAM on semen-fertilization capacity in White Leghorn (WL) male chicks was assayed in the present study. Sixty, 2-wk-old, male chicks were divided into two equal groups. The chicks from one group were injected im with 1 mg of TAM per kg of BW every other day; those from the second group were vehicle-treated (with corn oil) and served as controls. Each chick was paired with a virgin, WL laying hen. When semen was produced, the paired female was inseminated twice a week. The results revealed that TAM administration caused the early production of fertile semen, which resulted in the first normal descendants as early as 8 wk of age and brought about 100% of parenthood by the age of 88 days.
Content of phycoerythrin, phycocyanin, alophycocyanin and phycoerythrocyanin in some cyanobacterial strains: Applications (2018)

Cyanobacteria are unique prokaryotes, which are capable to perform oxygenic photosynthesis. Within these organisms, phycobilisomes (PBS) act as an antenna of the photosynthetic pigment apparatus. Phycobilisomes contain several phycobiliproteins (PBP): phycoerythrin (PE), phycocyanin (PC), allophycocyanin (APC) and phycoerythrocyanin (PEC). The application of phycobiliproteins in the biotechnology, food industry and medicine during the last years is rapidly increasing. The aim of our study was to assess the qualitative and quantitative content of phycoerythrin, phycocyanin, allophycocyanin and phycoerythrocyanin in 14 cyanobacterial strains kept in Plovdiv Algal Culture Collection (PACC) and 4 strains purchased from the Culture Collection of Autotrophic Organisms (CCALA). Our data demonstrated that three strains of <i>Microcoleus autumnalis</i> (PACC 5505, PACC 5522 and PACC 5527) have high potential to produce phycoerythrins (0.132, 0.201 and 0.136 mg/mL, respectively). Similarly, one <i>Microcoleus autumnalis</i> strain (PACC 5522) and one strain of <i>Leptolyngbya boryana</i> (CCALA 084) are suitable for biotechnological production of phycocyanins (0.051 and 0.264 mg/mL, respectively) as well as allophycocyanins (0.102 and 0.171 mg/mL, respectively). In addition, the data about the pigment content could be used as a biochemical marker for taxonomic purposes within the group.
Development of high Tc (greater than 100 K) Bi, Tl and Y-based materials as superconducting circuit elements. Annual report, February 1992-1993 (1993)

Results on this project over the past three years have shown that the Bi and Tl-based superconducting materials in bulk form are noticeably different from the Y-based 123 material in that superconductivity is considerably harder to achieve, maintain and reproduce. This is due primarily to the difficulty in obtaining the higher Tc phase in pure form since it commonly co-exists with other undesirable, lower Tc phases. In particular, it has been found that long processing times for calcining and firing (20 - 200 hrs.) and close control of temperatures which are very near the melting point are required in order to obtain higher proportions of the desirable, high Tc (2223) phase.
Synthesis of trinuclear gold(I) and gold(III) complexes containing the tridentate bis(diphenylphosphino)methanide ligand. Crystal structure of [Cl(C6F5)2Au{Ph2PCH(AuNC5H5)PPh2}AuCl] (1985)

The reaction of [Au(C6F5)2(Ph2PCHPPh2)] with [AuX(L)][X = Cl or Br, L = tetrahydrothiophen (tht) or AsPh3] leads to trinuclear complexes [X(C6F5)2Au{Ph2PCH (AuL) PPh2}AuX] containing the tridentate [Ph2PCH PPh2]– ligand. Displacement of tht with L = PPh3, pyridine, or 4-methylpyridine leads to the corresponding derivatives. The structure of [Cl(C6F5)2Au{Ph2PCH (AuNC5H5) PPh2}AuCl] has been determined by X-ray diffraction: space group P, a=11.664(5), b=14.790(6), c= 18.344(6)Å, α=111.30(4), β= 94.1 8(4), γ=107.64(4)°, and Z= 2; R= 0.075 for 4 627 reflections.
Frame Untangling for Unobtrusive Display-Camera Visible Light Communication (2016)

Pairing displays and cameras can open up convenient and "free" visible light communication channels. But in realistic settings, the synchronization between displays (transmitters) and cameras (receivers) can be far more involved than assumed in the literature. This study aims to analyze and model the temporal behaviors of displays and cameras to make the visible light communication channel between the two more robust, while maintaining perceptual transparency of the transmitted data.
Side‐Chain Engineering for High‐Performance Conjugated Polymer Batteries (2021)

Abstract Conjugated polymers are attractive for energy storage but typically require significant amounts of conductive additives to successfully operate with thin electrodes. Here, side‐chain engineering is used to improve the electrochemical performance of conjugated polymer electrodes. Naphthalene dicarboximide (NDI)‐based conjugated polymers with ion‐conducting ethylene glycol (EG) side chains ( PNDI‐T2EG ) and non‐ion‐conducting 2‐octyldodecyl side chains ( PNDI‐T2 ) are synthesized, tested, and compared. For thick (20 µ m, 1.28 mg cm −2 ) electrodes with a 60 wt% polymer, the PNDI‐T2EG electrodes exhibit 66% of the theoretical capacity at an ultrafast charge–discharge rate of 100C (72 s per cycle), while the PNDI‐T2 electrodes exhibit only 23% of the theoretical capacity. Electrochemical impedance spectroscopy measurements on thin (5 µm, 0.32 mg cm −2 ), high‐polymer‐content (80 wt%) electrodes reveal that PNDI‐T2EG exhibits much higher lithium‐ion diffusivity ( D Li+ = 7.01 × 10 −12 cm 2 s −1 ) than PNDI‐T2 ( D Li+ = 3.96 × 10 −12 cm 2 s −1 ). PNDI‐T2EG outperforms most previously reported materials in thick, high‐polymer‐content electrodes in terms of rate performance. The results demonstrate that the rate performance and capacity are significantly improved through the incorporation of EG side chains, and this work demonstrates a route for increasing the rate of ion transport in conjugated polymers and improving the performance and capacity of conjugated‐polymer‐based electrodes.