gebhart/patrepeval huggingface dataset:
Blood supply to the maxillary sinus relevant to sinus floor elevation procedures (1999)

The maxillary blood supply is essential for preserving the vitality of the affected maxillary region, integration of the grafting material, and wound healing such as following sinus floor elevation. Although it is well established that edentulous maxillae demonstrate a decreasing vascularity as bone resorption progresses, the vascular conditions relevant to sinus floor elevation procedures have not been investigated yet. This study deals with maxillary arteries relevant to sinus floor elevation surgery and examines the vascularization of the lateral maxilla after tooth loss. The vessels of the lateral maxilla of 18 maxillary specimens (10 male, 8 female, mean age 67 years) were prepared anatomically and the local main arteries, the number of macroscopically discernible branches and anastomoses, their calibers, and the distance between the caudal main branches and the alveolar ridge recorded. The lateral maxilla is supplied by branches of the posterior superior alveolar artery (PSAA) and the infraorbital artery (IOA) that form an anastomosis in the bony lateral antral wall, which also supplies the Schneiderian membrane. This intraosseous anastomosis was found in all of the specimens. Eight of 18 also showed an extraosseous anastomosis between PSAA and IOA, vestibular to the antral wall, giving off an average of 3 branches cranially and 5 branches caudally. The two anastomoses form a double arterial arcade to supply the lateral antral wall and, partly, the alveolar process. The PSAA had a mean caliber of 1.6 mm and exhibited an average of 2 endosseous and 1 extraosseous branches. The IOA had a mean diameter of 1.6 mm and showed an average of 1 endosseous and 3 extraosseous branches. The mean distance between the intraosseous anastomosis and the alveolar ridge was 19 mm in 2 defined measuring sites. Its mean length was 44.6 mm. The epiperiosteal vestibular anastomosis was situated further cranially at a mean distance of 23 to 26 mm from the alveolar ridge and had a mean length of 46 mm. The rather large caliber of the vessels supplying the lateral antral wall seems to be crucial to the fact that the periosteal blood supply is maintained even in severe maxillary atrophy and after complete disappearance of the centro-medullary vessels.
Effect of Welding Procedure and Aging on Ultrasonic Wave Propagation in Austenitic Stainless Steel (1980)

Various types of austenitic stainless steel (SS) were aged for up to 2500 h at a temperature of 600C to determine whether the resultant microstructural changes would affect the ultrasonic velocity and attenuation and thus the reliability of ultrasonic in-service inspections. Samples of Type 304 and 316 SS as well as 308, 308CRE, and 316 weld metal were examined. Velocity variations were less than 1%, and attenuation variations at frequencies below 10 MHz were not significant except in the anomalous case of one Type 316 SS weldmetal sample. That change may be due to unexpected microstructural changes associated with aging. The variation in the samples attributed to aging is therefore not expected to have a deleterious effect on ultrasonic in-service inspection of stainless steel reactor components.
Activation and serine phosphorylation of the p56 lck protein tyrosine kinase in response to antigen receptor cross-linking in B lymphocytes. (1994)

We show that cross-linking the B cell AgR with anti-Ig Abs activates p56lck (Lck) in both the immature B cell line WEHI-231 and mature resting B cells from mouse spleen. Anti-Ig-stimulated Lck activity peaked after 1 to 2 min, but remained elevated for at least 15 min. Consistent with the proposed role for src family tyrosine kinases in AgR signaling, we found that Lck could phosphorylate the cytoplasmic tails of the Ig-alpha and Ig-beta components of the B cell AgR in vitro. Lck phosphorylated both of the tyrosines in the Ig-beta AgR homology motif and one of the two tyrosines in the Ig-alpha AgR homology motif. Finally, we show that AgR ligation in B cells caused a significant portion of the Lck to migrate with an apparent molecular mass of 60 kDa on SDS-PAGE gels. Conversion of p56lck to p60lck was maximal at 5 to 15 min, at which times Lck activity in the cells was decreasing. This Lck "band shift" has been observed previously in activated T cells and correlates with phosphorylation of Lck at serine 59. We show that the 60-kDa form of Lck induced by AgR cross-linking in B cells is also phosphorylated at serine 59. Phosphorylation of Lck at this site in vitro decreases its activity. Thus, in B cells, AgR cross-linking activates Lck and subsequently activates a kinase that phosphorylates Lck at serine 59, a potential negative regulatory site.
14. METALLOINTERCALATORS AND METALLOINSERTORS: STRUCTURAL REQUIREMENTS FOR DNA RECOGNITION AND ANTICANCER ACTIVITY (2018)

Titanium(IV) coordination complexes represent attractive alternatives to platinumbased anticancer drugs. The advantage of the titanium metal lies in its low toxicity, and the hydrolysis of titanium(IV) coordination complexes in biological water-based environment to the safe and inert titanium dioxide is an enormous benefit. On the other hand, the rapid hydrolysis of titanium(IV) complexes in biological environment and their rich aquatic chemistry hampered the exploration and the development of effective compounds. Titanium(IV) complexes were the first to enter clinical trials for cancer treatment following the success of platinum-based chemotherapy, with the pioneering compounds titanocene dichloride and budotitane. Despite the high efficacy and low toxicity observed in vivo, the compounds failed the trials due to insufficient efficacy to toxicity ratio and formulation complications. The rapid hydrolysis of the complexes led to formation of multiple undefined aggregates and difficulties in isolating and identifying the particular active species and its precise cellular target. Numerous derivatives with different labile ligands or substitutions on the inert ones contributed to improve the complex anticancer features, and the best ones were comparable with, and occasionally better than cisplatin. Hydrolytic stability was improved in some cases but remained challenging. The following generation of phenolato-based complexes that came three decades later exhibited high activity and markedly improved stability, where no dissociation was observed for weeks in biological solutions. Complexes of no labile ligands whatsoever that remain intact in solution demonstrated in vitro and in vivo efficacy, with no signs of toxicity to the treated animals. Mechanistic insights gained for the different complexes analyzed include, among others, possible interaction with DNA and induction of apoptosis. Such complexes are highly promising for future exploration and clinical development.
Maori Land March, 1975 (1975)

Quantity: 13 b&w original photographic print(s) (as file prints). 1 photocopy/ies in one folder.
Shrinkage-based similarity metric for cluster analysis of microarray data (2003)

The current standard correlation coefficient used in the analysis of microarray data was introduced by M. B. Eisen, P. T. Spellman, P. O. Brown, and D. Botstein [(1998) Proc. Natl. Acad. Sci. USA 95, 14863-14868]. Its formulation is rather arbitrary. We give a mathematically rigorous correlation coefficient of two data vectors based on James-Stein shrinkage estimators. We use the assumptions described by Eisen et al., also using the fact that the data can be treated as transformed into normal distributions. While Eisen et al. use zero as an estimator for the expression vector mean mu, we start with the assumption that for each gene, mu is itself a zero-mean normal random variable [with a priori distribution N(0,tau 2)], and use Bayesian analysis to obtain a posteriori distribution of mu in terms of the data. The shrunk estimator for mu differs from the mean of the data vectors and ultimately leads to a statistically robust estimator for correlation coefficients. To evaluate the effectiveness of shrinkage, we conducted in silico experiments and also compared similarity metrics on a biological example by using the data set from Eisen et al. For the latter, we classified genes involved in the regulation of yeast cell-cycle functions by computing clusters based on various definitions of correlation coefficients and contrasting them against clusters based on the activators known in the literature. The estimated false positives and false negatives from this study indicate that using the shrinkage metric improves the accuracy of the analysis.
CONSERVATION STATUS OF THREATENED FISHES IN WARNER BASIN, OREGON (1990)

(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Techniques to quantify vascular ingrowth in soft tissue biomaterials (1988)

Due to the character of the original source materials and the nature of batch digitization, quality control issues may be present in this document. Please report any quality issues you encounter to digital@library.tamu.edu, referencing the URI of the item.
Sharing Begins at Home: How Continuous and Ubiquitous FAIRness Can Enhance Research Productivity and Data Reuse (2022)

The broad sharing of research data is widely viewed as critical for the speed, quality, accessibility, and integrity of science. Despite increasing efforts to encourage data sharing, both the quality of shared data and the frequency of data reuse remain stubbornly low. We argue here that a significant reason for this unfortunate state of affairs is that the organization of research results in the findable, accessible, interoperable, and reusable (FAIR) form required for reuse is too often deferred to the end of a research project when preparing publications-by which time essential details are no longer accessible. Thus, we propose an approach to research informatics in which FAIR principles are applied <i>continuously</i>, from the inception of a research project and <i>ubiquitously</i>, to every data asset produced by experiment or computation. We suggest that this seemingly challenging task can be made feasible by the adoption of simple tools, such as lightweight identifiers (to ensure that every data asset is findable), packaging methods (to facilitate understanding of data contents), data access methods, and metadata organization and structuring tools (to support schema development and evolution). We use an example from experimental neuroscience to illustrate how these methods can work in practice.
Muscarinic Modulation of the Vasodilatory Effects of Vasoactive Intestinal Peptide at the Rat Thyroid Gland (1991)

In the thyroid gland, vasoactive intestinal peptide (VIP) and acetylcholine (ACh) are found in nerve fibers associated with secretory cells and blood vessels. We have, therefore, initiated studies to explore the actions of and interactions between cholinergic agents and VIP in the regulation of thyroid vascular conductance (VC). Thyroid and other organ blood flows were measured using radiolabelled (141Ce) microspheres injected directly into the left cardiac ventricle of anesthetized male rats. The mean systemic arterial pressure was monitored and used in the calculation of organ VC (blood flow/arterial pressure). Plasma TSH, T3, and T4 levels before and after infusions were measured by RIA. The acute administration of ACh (3 x 10(-8) mol/100 g BW) over 4 min increased thyroid VC, whereas nicotine (10(-7) mol/100 g BW) had no such effect. Circulating TSH and thyroid-hormone levels following ACh or nicotine were not different from those in vehicle-treated animals at 20 min or 2 h after infusion. This observation suggested that ACh acts through muscarinic receptors at the thyroid gland to increase VC. In order to extend these observations and to evaluate whether VIP might exert any of its thyroidal effects on VC via muscarinic receptors, we assessed the effects of ACh, methacholine chloride (MCC), and VIP in the presence and absence of the muscarinic receptor blocker atropine. Rats were treated intravenously with saline or atropine (3 mg/kg) 20 min before intravenous infusions of vehicle, ACh (3 x 10(-8) mol/100 g BW), MCC (5 x 10(-9) mol/100 g BW), or VIP (10(-11) mol/100 g BW).(ABSTRACT TRUNCATED AT 250 WORDS)
HSAs: More Than a (Tax) Shelter, Not Quite a House (2005)

Health care economists and policy experts have advanced a variety of ideas for helping the 45 million people who lack health insurance and the millions more who are underinsured. Their proposals range from market-based health savings accounts and income-based tax subsidies to a government single-payer system. This is one of 3 perspectives VM has solicited on health care financing in the US that explore some of these initiatives for expanding coverage.
The Garbage Collection Handbook (2023)

Published in 1996, Richard Jones's Garbage Collection was a milestone in the area of automatic memory management. Its widely acclaimed successor, The Garbage Collection Handbook: The Art of Automatic Memory Management, captured the state of the field in 2012. Modern technology developments have made memory management more challenging, interesting and important than ever. This second edition updates the handbook, bringing together a wealth of knowledge gathered by automatic memory management researchers and developers over the past sixty years. The authors compare the most important approaches and state-of-the-art techniques in a single, accessible framework. The book addresses new challenges to garbage collection made by recent advances in hardware and software. It explores the consequences of these changes for designers and implementers of high performance garbage collectors. Along with simple and traditional algorithms, the book covers state-of-the-art parallel, incremental, concurrent and real-time garbage collection. Algorithms and concepts are often described with pseudocode and illustrations. Features of this edition Provides a complete, up-to-date, and authoritative sequel to the 1996 and 2012 books Offers thorough coverage of parallel, concurrent, and real-time garbage collection algorithms Discusses in detail modern, high-performance commercial collectors Explains some of the trickier aspects of garbage collection, including the interface to the run-time system Over 90 more pages including new chapters on persistence and energy-aware garbage collection Backed by a comprehensive online database of over 3,400 garbage collection-related publications The adoption of garbage collection by almost all modern programming languages makes a thorough understanding of this topic essential for any programmer. This authoritative handbook gives expert insight on how different collectors work as well as the various issues currently facing garbage collectors. Armed with this knowledge, programmers can confidently select and configure the many choices of garbage collectors. &nbsp; &nbsp; https://gchandbook.org
Quantum well intersubband heterodyne infrared detection up to 82 GHz (1995)

We demonstrate the heterodyne detection of two CO2 laser signals offset in frequency up to 82.16 GHz using a multiple quantum well intersubband infrared photodetector. The high frequency is reached by down conversion using the detector itself as a microwave or millimeter-wave mixer.
Detoxification of High Tannin Sorghum Grains (1986)

One in vitro and two in vivo experiments were conducted to determine appropriate methodology for and effects of detoxifying Darset, Redlan, and one commercial hybrid brown sorghum grain variety in threonine-deficient and nutritionally complete poultry rations. The detoxification procedure, which involves adding water to sorghum grain to bring dry matter to 70% and subsequent anaerobic incubation at 32 C, removes up to 100% of the chemically detectable tannin. Rate of tannin elimination was dependent upon sorghum grain variety with commercial brown sorghum requiring approximately 3 days longer than the Darset for tannin elimination. Detoxification of high tannin sorghum grains improved (P less than .05) growth rate and feed efficiency dramatically in threonine-deficient, crystalline amino acid-fortified rations; the same process applied to low tannin sorghum grains was without benefit. The desirable effects of this type of grain processing appear to be due to the reduced grain tannin content. Including detoxified sorghum grains in a practical-type broiler ration failed to elicit a weight gain response although feed efficiency was improved by 13% over untreated sorghum and 3% over corn grain. Lack of a gain response was likely due to the excess protein included in the basal diet. This type of grain processing offers an alternative method of reducing sorghum grain tannin content and is likely of greatest value in rations containing marginal indispensable amino acid and protein levels.
Profiling of Glycosidase Activities Using Coumarin-Conjugated Glycoside Cocktails (2007)

Glycosidases are a large subgroup of carbohydrate-processing enzymes that hydrolytically cleave the glycosidic bond. Glycans formed by the action of glycosidases are involved in various biological processes. Genetic abnormalities in glycosidases are associated with inherited diseases. Thus, characterization of the catalytic activities of glycosidases is of great importance. Herein, we describe a simple and rapid approach for determining glycosidase activity profiles using coumarin-conjugated glycoside cocktails. [reaction: see text].
The role of an extracellular polysaccharide produced by the marine Pseudomonas sp. S9 in cellular detachment during starvation (1989)

An exopolysaccharide polymer is produced by the marine Pseudomonas sp. S9 in response to complete energy and nutrient starvation. The presence of this polysaccharide on the cell surface and its subsequent release have been shown to be associated with both adhesion and detachment of the bacterial cells. Detachment from a hydrophobic surface was correlated to the presence of the exopolysaccharide on detached S9 cells. The exopolysaccharide was detected, using immunofluorescence microscopy, on surface-bound cells after only 15 min of exogenous energy and nutrient deprivation. This technique did not reveal any significant amounts of exopolysaccharide on starving bulk phase cells prior to 3 h of starvation. Cells that detached after 5.5 h of starvation had low cell surface hydrophobicity values and increased amounts of cell-bound exopolysaccharide. In contrast, cells that became detached during the first 5.5 h of starvation showed increasing hydrophobicity values during prolonged bulk phase starvation.
Impact of Viscous Fingering on the Prediction of Optimum WAG Ratio (2007)

Summary In miscible flooding, injection of solvent is often combined with water to reduce the mobility contrast between injected and displaced fluids and control the degree of fingering. Using traditional fractional-flow theory, Stalkup estimated the optimum watersolvent ratio (or WAG ratio) when viscous fingering effects are ignored, by imposing that the solvent and water fronts travel at the same speed. Here we study how the displacement efficiency and the mobility ratio across the solvent front vary with the WAG ratio when fingering is included in the analysis. We do so by computing analytical solutions to a 1D model of two-phase, three-component, first-contact miscible flow that includes the macroscopic effects of viscous fingering. The macroscopic model, originally proposed by Blunt and Christie (1993, 1994), employs an extension of the Koval fingering model to multiphase flows. The premise is that the only parameter of the model—the effective mobility ratio—must be calibrated dynamically until self-consistency is achieved between the input value and the mobility contrast across the solvent front. This model has been extensively validated by means of high-resolution simulations that capture the details of viscous fingering and carefully-designed laboratory experiments. The results of this paper suggest that, while the prediction of the optimum WAG ratio does not change dramatically by incorporating the effects of viscous fingering, it is beneficial to inject more solvent than estimated by Stalkup's method. We show that, in this case, both the pore volumes injected (PVI) for complete oil recovery and the degree of fingering are minimized.
REST API Design Patterns for SDN Northbound API (2014)

REST architectural style gains increasing popularity in the networking protocol design, and it has become a prevalent choice for northbound API of Software-Defined Networking (SDN). This paper addresses many critical issues in RESTful networking protocol design, and presents a framework on how a networking protocol can be designed in a truly RESTful manner, making it towards a service oriented data networking. In particular, we introduce the HTTP content negotiation mechanism which allows clients to select different representation formats from the same resource URI. Most importantly, we present a hypertext-driven approach, so that hypertext links are defined between REST resources for the networking protocol to guide clients to identify the right resources rather than relying on fixed resource URIs. The advantages of our approach are verified in two folds. First, we show how to apply our approach to fix REST design problems in some existing northbound networking APIs, and then we show how to design a RESTful northbound API of SDN in the context of OpenStack. We implemented our proposed approach in the northbound REST API of SOX, a generalized SDN controller, and the benefits of the proposed approach are experimentally verified.
Nonlinear Control of a Distributed System: Simulation and Experimental Results (1987)

A nonlinear active vibration damper has been developed which uses a spatially distributed piezoelectric actuator, polyvinylidene flouride, to achieve active vibration control of a cantilever beam. The control algorithm was derived using Lyapunov’s Second Method. All modes of the beam can be controlled simultaneously if the angular velocity of the tip of the beam is known. A simulation algorithm was developed to predict the effect of the control on the free decay of a single mode. A parameter study for the first mode was performed and compared to experimental results. The active damper has been tested successfully on two different scale structures.
Food Safety—Who Is Responsible? (2006)

Though scientists believe that issues of risk can be handled without appeal to values in general or ethics in particular, this is demonstrably false. The very notion of risk is enmeshed in a complex of social ethics. This is clearly true with regard to food safety. With this in mind, it is plausible to affirm that responsibility for food safety at a given point in the chain from producer to consumer rests with the person or entity under whose control the management of that risk most plausibly lies. This principle is illustrated with various examples and with clear cases of industry shouldering and avoiding responsibility. An additional ethical concern relevant to food safety arises from genetically modified foods. Given that the situation here is uncertain and risk unknown, it is hard to see who is responsible for managing such risks. It is arguable that this situation militates in favor of labeling, since consumers are in effect research subjects. The reasonable moral approach to risk we have outlined is jeopardized by the societal tendency towards "victimology" and abrogation of personal responsibility. In such a world, it is incumbent on industry to educate the public with regard to consumer minimization of food safety risks, the impossibility of zero-risk situations, and the economic costs to freedom of protectionism.