gebhart/patrepeval huggingface dataset:
A simple operation of a plasma-electrode pockel’s cell for the laser megajoules (2002)

We report on a simple way to operate plasma-electrode pockel’s cells (PEPC), which are used as large-aperture optical switches in laser drivers for inertial-confinement fusion facilities. In the basic operation of a PEPC, one needs to produce a plasma in each of two gas-filled cells placed on opposite sides of an appropriate crystal plate. Between the resulting highly conductive electrodes, a high-voltage pulse is applied to produce a uniform electric field in the crystal, which then undergoes the Pockel’s effect. We have developed a simple PEPC design in which the high-voltage pulse can be directly applied between the gascells without prior ionization of the gas (by a high-current plasma discharge). With reasonable operating parameters, this regime meets the PEPC optical switching requirements for the laser megajoules. In this paper, we present experimental results of this simple regime that strongly simplifies the PEPC concept and improves its reliability.
Display of functional nucleic acid polymerase on Escherichia coli surface and its application in directed polymerase evolution (2020)

We report a first of its kind functional cell surface display of nucleic acid polymerase and its directed evolution to efficiently incorporate 2'-O-methyl nucleotide triphosphates (2'-OMe-NTPs). In the development of polymerase cell surface display, two autotransporter proteins (Escherichia coli adhesin involved in diffuse adherence and Pseudomonas aeruginosa esterase A [EstA]) were employed to transport and anchor the 68-kDa Klenow fragment (KF) of E. coli DNA polymerase I on the surface of E. coli. The localization and function of the displayed KF were verified by analysis of cell outer membrane fractions, immunostaining, and fluorometric detection of synthesized DNA products. The EstA cell surface display system was applied to evolve KF for the incorporation of 2'-OMe-NTPs and a KF variant with a 50.7-fold increased ability to successively incorporate 2'-OMe-NTPs was discovered. Expanding the scope of cell-surface displayable proteins to the realm of polymerases provides a novel screening tool for tailoring polymerases to diverse application demands in a polymerase chain reaction and sequencing-based biotechnological and medical applications. Especially, cell surface display enables novel polymerase screening strategies in which the heat-lysis step is bypassed and thus allows the screening of mesophilic polymerases with broad application potentials ranging from diagnostics and DNA sequencing to replication of synthetic genetic polymers.
An Improvement of Communication Environment for ETC System by Using Transparent EM Wave Absorber (2005)

When a large-size car exists on the ETC lane (Electronic Toll Collection System), there is the possibility that the interference on the adjacent lane occurs by the scattering waves from one. In this paper, we propose a new improvement method which the transparent EM wave absorber is placed between the ETC lane and the adjacent one in order to suppress the scattering waves from a large-size car. Therefore, we design the transparent EM wave absorber which consists of the transparent resistive and conductive films. Then, this absorber is produced, and its reflection and transmission coefficients are evaluated. In addition, its transmittance in optics is evaluated. As the results, the reflectivity of this absorber is obtained lower than -20dB in the oblique incident angle from 0° to 30 at 5.8 GHz circular polarized wave, abbreviated as CP wave, and also the transmittivity is obtain lower than -27 dB in the oblique incident angle from 0° to 70°, respectively. On the other hand, the transmittance in optics is obtained higher than 60%. Moreover, we study experimentally on the ETC system with placing this absorber between the ETC lane and the adjacent one. We measured the distribution of receiving power on the adjacent lane, when a water sprinkler existed on the ETC lane. As a result, it is confirmed that the receiving power on the adjacent lane could be realized lower than -70.5 dBm, and then a new improvement method has proven to be very useful in the ETC system.
Evaluation of the VIA® Blood Chemistry Monitor for Glucose in Healthy and Diabetic Volunteers (2008)

This study demonstrated that the VIA blood chemistry monitor for glucose can reliably sample blood frequently for a prolonged period of time safely and effectively in diabetic and nondiabetic volunteers. Agreement between the two devices was the closest at normal glucose concentrations. After correcting for a glucose-dependent bias between the devices, the MARD was consistently less than 10% for all glucose ranges.
Identification of Nuclear Export Inhibitors with Potent Anticancer Activity In vivo (2009)

The export protein CRM1 is required for the nuclear export of a wide variety of cancer-related "cargo" proteins including p53, c-Abl, and FOXO-3A. Leptomycin B (LMB) is a highly specific inhibitor of CRM1 with significant in vitro potency but limited in vivo efficacy due to toxicity. We now report a series of semisynthetic LMB derivatives showing substantially improved therapeutic windows. Exposure of cancer cells to these compounds leads to a rapid and prolonged block of nuclear export and apoptosis. In contrast to what is observed in cancer cells, these agents induce cell cycle arrest, but not apoptosis, in normal lung fibroblasts. These new nuclear export inhibitors (NEI) maintain the high potency of LMB, are up to 16-fold better tolerated than LMB in vivo, and show significant efficacy in multiple mouse xenograft models. These NEIs show the potential of CRM1 inhibitors as novel and potent anticancer agents.
Facile synthesis of 3‐substituted [1,2,4]triazino[3,4‐f]purine‐4,6,8‐trione derivatives (2001)

Abstract A new synthetic route to build the [1,2,4]triazino[3,4‐ f ]purine nucleus is described. The novel [1,2,4]‐triazino[3,4‐ f ]purine‐4,6,8(l H ,7 H ,9 H )‐trione derivatives were obtained by condensation of 8‐hydrazinotheophylline with appropriate glyoxylic acids via the intermediate hydrazones.
Rational function decomposition (1991)

Article Rational function decomposition Share on Author: Richard Zippel Cornell University, Ithaca, NY Cornell University, Ithaca, NYView Profile Authors Info & Claims ISSAC '91: Proceedings of the 1991 international symposium on Symbolic and algebraic computationJune 1991 Pages 1–6https://doi.org/10.1145/120694.120695Online:01 June 1991Publication History 35citation571DownloadsMetricsTotal Citations35Total Downloads571Last 12 Months16Last 6 weeks1 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Recent Wind-Driven Variability in Atlantic Water Mass Distribution and Meridional Overturning Circulation (2017)

Abstract Interannual variability in the volumetric water mass distribution within the North Atlantic Subtropical Gyre is described in relation to variability in the Atlantic meridional overturning circulation. The relative roles of diabatic and adiabatic processes in the volume and heat budgets of the subtropical gyre are investigated by projecting data into temperature coordinates as volumes of water using an Argo-based climatology and an ocean state estimate (ECCO version 4). This highlights that variations in the subtropical gyre volume budget are predominantly set by transport divergence in the gyre. A strong correlation between the volume anomaly due to transport divergence and the variability of both thermocline depth and Ekman pumping over the gyre suggests that wind-driven heave drives transport anomalies at the gyre boundaries. This wind-driven heaving contributes significantly to variations in the heat content of the gyre, as do anomalies in the air–sea fluxes. The analysis presented suggests that wind forcing plays an important role in driving interannual variability in the Atlantic meridional overturning circulation and that this variability can be unraveled from spatially distributed hydrographic observations using the framework presented here.
The facile fabrication of few-layer graphene and graphite nanosheets by high pressure homogenization (2015)

We demonstrated a facile and efficient approach for the fabrication of few-layer graphene in DMF and graphite nanosheets in water with the assistance of high pressure homogenization. This work provides a physical perspective for understanding the exfoliation of other layered materials in liquid phase exfoliation.
Sequence-specific interactions of a nuclear protein factor with the promoter region of a rice gene for α-amylase,RAmy3D (1994)

The expression of a rice gene for alpha-amylase, RAmy3D, in suspension-cultured cells is induced at the transcriptional level by the deprivation of sugars. Binding of a nuclear protein from suspension-cultured rice cells to the promoter region of the RAmy3D gene was studied by gel-retardation and DNase I footprinting assays. Gel-retardation assays indicated that a 358-bp fragment of the promoter region interacted specifically with a protein factor from suspension-cultured cells. DNase I footprinting analysis allowed us to define three protein-binding regions. Each of these protein-binding sequences contained the GCCG G/C CG motif, which is specifically present in the promoter region of the sugar-regulated gene, RAmy3D, for rice alpha-amylase and not in that of the gibberellin-regulated RAmy1A gene. Subsequent cross-competition experiments using gel-retardation assay and synthetic oligonucleotides showed that the GCCG G/C CG motifs directly mediated the binding of a nuclear protein. These observations are discussed in relation to expression of the gene for alpha-amylase in suspension-cultured cells.
Electric Polarizability of Some Diatomic Molecules (1963)

A variation-perturbation method is employed for the calculation of the electric polarizability tensor of a series of diatomic molecules (H2, Li2, N2, LiH, HF, LiF, CO). The SCF—LCAO—MO functions of Ransil are used as unperturbed solutions and appropriately orthogonalized perturbation functions are introduced to account for the effect of the electric field. For the three molecules (H2, N2, CO) for which experimental data are available, reasonable agreement between the theoretical and the measured values is obtained. However, the calculations appear to somewhat overestimate the electric polarizability, particularly so for the parallel component of the tensor; possible theoretical refinements to reduce this error are discussed.
New Ways or Old Tricks? The World Bank’s Gender Strategy and Its Implications for Health (2019)

This paper provides a critical examination of the World Bank’s document, “World Bank Group Gender Strategy: Gender Equality, Poverty Reduction, and Inclusive Growth.” While the World Bank suggests that this paper is a distinction from past practices, others maintain that it is a continuation of previous neoliberal strategies. Thus, the aim of this analysis is to elucidate the implications of the proposed strategies on both gender equality and health equity. The analytical framework derives from both feminist political economy and the political economy of health literature. Within the document there is a direct emphasis on privatization and deregulation. Moreover, there is a clear re-articulation of both the state and female-citizenship: the former is presented as an “enabling agent,” and the latter depoliticized. Accordingly, it is argued that the promotion of macroeconomic strategies leads to the exaggeration of gender inequalities due to the perpetuation and crystallization of social inequalities. This consequently leads to the entrenchment of health inequities. These health inequities are compounded by the promotion of a “reduced state” that focuses on constructing a “workfare” state and a citizen who is resigned to community politics. Thus, instead of promoting gender equality, this report reflects a tendency toward its perpetuation.
Antidepressants and Anxiolytics (2009)

Depression and anxiety are among the most common psychiatric disorders. Worldwide sales of antidepressant drugs of more than $20 billion make this one of the most important classes of central nervous system medicines. Although some may think of depression as a form of moral deficiency from which indi-viduals could get better if they just “pulled themselves up by the bootstraps,” the reality is that it is an illness, not a choice, and it represents a major cause of dis-ability, preventing sufferers from work and pleasure. It is also a syndrome of different symptoms, only one of which is depressed mood. The diagnostic criteria suggested by the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV; Table 14–1), make this clear and readily distinguish major depression from normal reactions to life events such as bereavement.
Catalytic Behavior of Au Core / Pd Shell Bimetallic Nanoparticles on Silica Prepared by Sonochemical and Sol–Gel Processes (2000)

Abstract A unique catalyst, Au core and Pd shell bimetallic nanoparticles immobilized on porous silica exhibiting a considerable high activity for the hydrogenation of cyclohexene, was prepared via two steps composed of the sonochemical reduction method and the sol–gel process under a low temperature condition.
Fig. S6 from Targeting Lymphoma-associated Macrophage Expansion via CSF1R/JAK Inhibition is a Therapeutic Vulnerability in Peripheral T-cell Lymphomas (2023)

&lt;p&gt;Fig. S6: GSEA in LAM&lt;/p&gt;
Illness and exposure to negative life experiences in adolescence: two sides of the same coin? A study of 15-year-olds in Oslo, Norway (2004)

Aim: To investigate associations between negative life experiences and common illnesses among adolescents. Methods: Cross-sectional questionnaire study carried out at all lower secondary schools (10 grade) in Oslo, Norway, during 2000 and 2001 (n= 8316 pupils). Different negative life experiences and illnesses were addressed. Results: The participation rate was 88%. Among reported negative life experiences last year were a pressure felt to succeed (62%), death of a close person (26%), exposure to physical violence (22%), bullying at school (15%) and sexual violation (4%). A large number of the pupils had some chronic illness: hay fever (38%), eczema (29%) and asthma (13%). Reported illnesses the previous 12 month were: headache (56%), painful neck or shoulders (35%), sore throat at least three times (15%), lower respiratory tract infection (9%) and mental problems for which help was sought (7%). During the week prior to the survey, 26% of all girls had symptoms of a depressive disorder, while this applied to 10% of all boys. Fifty-three percent of the boys (29% of the girls) who had depressive symptoms had been exposed to physical violence. Sexually violated boys had a high probability for seeking help for mental problems (OR = 4.9) and for frequent episodes of sore throat (OR = 2.5). Corresponding odds ratios for girls were 1.7 and 2.5, respectively. Conclusion: Common illnesses in adolescence are significantly associated with negative life experiences. In clinical encounters with adolescents not only should the presenting complaints be addressed, but also other common illnesses and relevant background factors such as negative life events.
Controlling Patient Expectations: Important in Maximizing Patient Satisfaction (2006)

&lt;P&gt;One goal of patient care is happy, healthy patients. We physicians know that at one level, but it is surprisingly easy to forget. For example, we assume that a person whose visual acuity has been improved from 20/60 to 20/20 will be happy. Clearly, there is a relationship of some sort between level of acuity and ability to function, and a relationship between the ability to function and happiness. Indeed, we physicians tend to underestimate the importance of visual ability in our patients.&lt;SUP&gt;1-3&lt;/SUP&gt;&lt;/P&gt;&lt;H4&gt;AUTHOR&lt;/H4&gt; &lt;P&gt;From the Glaucoma Service, Wills Eye Hospital/Jefferson Medical College, Philadelphia, Pennsylvania.&lt;/P&gt;&lt;P&gt;Address reprint requests to George L. Spaeth, MD, Wills Eye Hospital, 840 Walnut Street, Philadelphia, PA 19107.&lt;/P&gt;
Resolving Power Consumption of Variable Power Electronic Loads Using Nonintrusive Monitoring (2007)

This paper demonstrates a new estimator to resolve the average power consumption of a variable-speed drive (VSD) from other constant power loads using a spectral estimation method and a switching function technique for nonintrusive load monitoring (NILM) applications. The estimator uses the rectifier switching function to create adaptive estimating functions for the fundamental power from a finite set of current harmonics generated by the VSD. Experimental results show that the proposed VSD power estimator can significantly improve NILM's ability to resolve the VSD power consumption under small input voltage variation.
The effect of urinary nitrogen loading rate and a nitrification inhibitor on nitrous oxide emissions from a temperate grassland soil (2014)

SUMMARY Nitrous oxide (N 2 O) emissions associated with urine nitrogen (N) deposition during grazing are a major component of greenhouse gas emissions from domestic livestock. The present study investigated the relationship between urine N loading rate and the efficacy of a nitrification inhibitor, dicyandiamide (DCD), on cumulative N 2 O emissions from a grassland soil in Ireland over 80 and 360-day periods in 2009/10 and 2010/11. A diminishing curvilinear relationship between urine N rate and cumulative N 2 O emissions was observed in both years. Despite this increase in cumulative N 2 O emissions, the emission factor (EF 3 ) for N 2 O decreased with increasing urine N rate from, on average, 0·24 to 0·10% (urine applied at 300 and 1000 kg N/ha, respectively), during an 80-day measurement period. This was probably the result of a factor other than N, such as carbon (C), limiting the production of N 2 O. The efficacy of DCD varied with urine N loading rate, and inter-annual variability in efficacy was also observed. Dicyandiamide was effective at reducing N 2 O production for 50–80 days after urine application, which accounted for the major period of elevated daily flux. However, DCD was ineffective at reducing N 2 O production after this period, which was likely a result of its removal from the soil via degradation and leaching.
Efficacy of two ethanol-based skin antiseptics on the forehead at shorter application times (2007)

The clear and coloured skin antiseptics applied for 2.5 min on the skin of the forehead fulfilled the efficacy requirements for skin antisepsis. The shorter application time on skin with a high density of sebaceous glands will allow to act more efficiently in clinical practice.
ChemInform Abstract: Preparation of 2‐Azido‐4‐O‐benzoyl‐2,6‐dideoxy‐3‐O‐methyl‐β‐D‐ allopyranose and Its Disaccharide Derivative. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Synthesis and Properties of Photo-Cross-Linkable Hyperbranched Poly(urethane)s Containing Both Terminal Methacryloyl Groups and Carboxyl Groups (2007)

The synthesis and photopolymerization of alkaline-developable hyperbranched polyurethane (HBPUMA-COOH) were examined. The reaction of dicyclohexylmethane 4,4‘-diisocyanate (CMDI) and trimethylolpropane (TMP) in the presence of 2-methacryloyloxyethyl isocyanate (MOI) was carried out to give the soluble hyperbranched polyurethane (HBPUMA) with terminal methacryloyl groups in satisfactory yield. After that, HBPUMA-COOH was synthesized by the reaction of HBPUMA and cis-1,2,3,6-tetrahydrophthalic anhydride (THPA). The photoradical polymerization of HBPUMA-COOH was examined in the presence of 2-methyl-1-[4-(methylthio)phenyl]-2-morpholinopropan-2-one (Irgacure 907) as a photoinitiator in the film state upon UV irradiation to afford the corresponding cured film quantitatively. It was found that the tensile strength of the resulting cured film of HBPUMA-COOH was higher than those of the HBPUMA and linear one. The negative patterning property of HBPUMA-COOH also had 5 μm line and space pattern resolution by UV irradiation with 150 mJ/cm2. Furthermore, it was cleared that the photocured HBPUMA and HBPUMA-COOH showed very low birefringence.
Study of surface passivation as a function of InP closed-ampoule solar cell fabrication processing variables (1990)

The effects of various surface preparation procedures, including chemical treatment and anodic or chemical oxidation, closed-ampoule diffusion conditions, and post-diffusion surface preparation and annealing conditions, on the passivating properties of InP have been investigated in order to optimize the fabrication procedures of n/sup +/p InP solar cells made by closed-ampoule diffusion of sulfur into p-type InP. The InP substrates used were p-type Cd-doped to a level of 1.7*10/sup 16/ cm/sup -3/, Zn-doped to levels of 2.2*10/sup 16/ and 1.2*10/sup 18/ cm/sup -3/, and n-type S-doped to 4.4*10/sup 18/ cm/sup -3/. The passivating properties have been evaluated from photoluminescence and conductance-voltage characteristics data. Good agreement was found between the level of surface passivation and the composition of different surface layers as revealed by X-ray photoelectron spectroscopy (XPS) analysis.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
A Look at the Effect of Sample Design on Generalization through the Lens of Spectral Analysis (2019)

This paper provides a general framework to study the effect of sampling properties of training data on the generalization error of the learned machine learning (ML) models. Specifically, we propose a new spectral analysis of the generalization error, expressed in terms of the power spectra of the sampling pattern and the function involved. The framework is build in the Euclidean space using Fourier analysis and establishes a connection between some high dimensional geometric objects and optimal spectral form of different state-of-the-art sampling patterns. Subsequently, we estimate the expected error bounds and convergence rate of different state-of-the-art sampling patterns, as the number of samples and dimensions increase. We make several observations about generalization error which are valid irrespective of the approximation scheme (or learning architecture) and training (or optimization) algorithms. Our result also sheds light on ways to formulate design principles for constructing optimal sampling methods for particular problems.
Synthesis of core–shell ZSM-5@meso-SAPO-34 composite and its application in methanol to aromatics (2015)

A core/shell-structured ZSM-5@meso-SAPO-34 composite catalyst was hydrothermally synthesized through overgrowing SAPO-34 molecular sieve on the external surface of ZSM-5.