gebhart/patrepeval huggingface dataset:
A Centralized Omnidirectional Multi-Camera System with Peripherally-Guided Active Vision and Depth Perception (2007)

The growing popularity of omnidirectional vision technology has spawned numerous multi-camera designs that integrate various different camera types. This paper presents an omnidirectional vision system that combines a catadioptric camera, a fisheye camera and an active perspective camera. Aligning these cameras vertically provides a number of beneficial features, such as allowing simple peripherally-guided active vision, depth perception and a near spherical composite omnidirectional field of view. By having the active camera rotate around the outer perimeter, it can attain complete spherical access to the environment. The triangulation performance is evaluated experimentally using a target fixed to a long translation stage. Static positions of the target are estimated using a stereo pair that consists of one active perspective camera and one omnidirectional camera. Overall, the system provides sufficient accuracy to facilitate further surveillance research.
Ischemic colitis and immunosuppression (1986)

The incidence of ischemic colitis in renal transplant recipients approaches 1 percent. The mortality in these patients with ischemic colitis is nearly 70 percent. Immunosuppressive agents have been implicated in the development of ischemic colitis. To study the effect of immunosuppressive agents on ischemic colitis, a 4-cm segment of the colon was devascularized in 27 male Fischer rats. The animals were divided into one control and two treatment groups. One treatment group received methylprednisolone and the other, azathioprine, in doses similar to those of renal transplant recipients. Both experimental groups, either separately or combined, showed significantly greater areas of colonic ischemic changes than did the control group. This study demonstrates that systemic administration of immunosuppressive agents may augment the development of ischemic colitis.
Discovering Interesting Patterns for Investment Decision Making with Glower C - a Genetic Learner Overlaid with Entropy Reduction (2000)

Prediction in financial domains is notoriously difficult for a number of reasons. First, theories tend to be weak or non-existent, which makes problem formulation open-ended by forcing us to consider a large number of independent variables and thereby increasing the dimensionality of the search space. Second, the weak relationships among variables tend to be nonlinear, and may hold only in limited areas of the search space. Third, in financial practice, where analysts conduct extensive manual analysis of historically well performing indicators, a key is to find the hidden interactions among variables that perform well in combination. Unfortunately, these are exactly the patterns that the greedy search biases incorporated by many standard rule algorithms will miss. In this paper, we describe and evaluate several variations of a new genetic learning algorithm (GLOWER) on a variety of data sets. The design of GLOWER has been motivated by financial prediction problems, but incorporates successful ideas from tree induction and rule learning. We examine the performance of several GLOWER variants on two UCI data sets as well as on a standard financial prediction problem (S&P500 stock returns), using the results to identify and use one of the better variants for further comparisons. We introduce a new (to KDD) financial prediction problem (predicting positive and negative earnings surprises), and experiment withGLOWER, contrasting it with tree- and rule-induction approaches. Our results are encouraging, showing that GLOWER has the ability to uncover effective patterns for difficult problems that have weak structure and significant nonlinearities.
Palladium‐Catalyzed Synthesis of (E)‐5‐(3‐Aminoallyl)‐Uridine‐5′‐O‐Triphosphates (2017)

This unit describes a simple, reliable, and efficient chemical method for the synthesis of 5-(3-aminoallyl)-2'-deoxyuridine-5'-O-triphosphate (AA-dUTP) and 5-(3-aminoallyl)-uridine-5'-O-triphosphate (AA-UTP), starting from the corresponding nucleoside triphosphate. The presented strategy involves regioselective iodination of nucleoside triphosphate using N-iodosuccinimide followed by the palladium-catalyzed Heck coupling with allylamine to provide the corresponding (E)-5-aminoallyl-uridine-5'-O-triphosphate in good yields. It is noteworthy that the protocol not only provides a high-purity product but also eliminates the use of toxic mercuric reagents. © 2017 by John Wiley & Sons, Inc.
Synthesis and polymerization of alkyl .alpha.-(Alkylsulfonyl)acrylates (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and polymerization of alkyl .alpha.-(Alkylsulfonyl)acrylatesE. Gipstein, C. G. Willson, and H. SachdevCite this: J. Org. Chem. 1980, 45, 8, 1486–1489Publication Date (Print):April 1, 1980Publication History Published online1 May 2002Published inissue 1 April 1980https://pubs.acs.org/doi/10.1021/jo01296a028https://doi.org/10.1021/jo01296a028research-articleACS PublicationsRequest reuse permissionsArticle Views299Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Endothelin‐1 mediates natriuresis but not polyuria during vitamin D‐induced acute hypercalcaemia (2017)

Acute hypercalcaemia increases urinary sodium and water excretion; however, the underlying molecular mechanism remains unclear. Because vitamin D-induced hypercalcaemia increases the renal expression of endothelin (ET)-1, we hypothesized that ET-1 mediates the effects of hypercalcaemia on renal sodium and water handling. Hypercalcaemia was induced in 8-week-old, parathyroid hormone-supplemented, male mice by oral administration of dihydrotachysterol (DHT) for 3 days. DHT-treated mice became hypercalcaemic and displayed increased urinary water and sodium excretion compared to controls. mRNA levels of ET-1 and the transcription factors CCAAT-enhancer binding protein β and δ were specifically increased in the distal convoluted tubule and downstream segments in DHT-treated mice. To examine the role of the ET system in hypercalcaemia-induced natriuresis and polyuria, mice were treated with the ET-1 receptor antagonist macitentan, with or without DHT. Mice treated with both macitentan and DHT displayed hypercalcaemia and polyuria similar to that in mice treated with DHT alone; however, no increase in urinary sodium excretion was observed. To identify the affected sodium transport mechanism, we assessed the response to various diuretics in control and DHT-treated hypercalcaemic mice. Amiloride, an inhibitor of the epithelial sodium channel (ENaC), increased sodium excretion to a lesser extent in DHT-treated mice compared to control mice. Mice treated with either macitentan+DHT or macitentan alone had a similar response to amiloride. In summary, vitamin D-induced hypercalcaemia increases the renal production of ET-1 and decreases ENaC activity, which is probably responsible for the rise in urinary sodium excretion but not for polyuria.
Enhancing the Magnetic Anisotropy of Cyano-Ligated Chromium(II) and Chromium(III) Complexes via Heavy Halide Ligand Effects (2010)

A method of increasing the axial zero-field splitting parameter for transition metal complexes of utility in the assembly of magnetic clusters is demonstrated through the use of heavy atoms as auxiliary ligands. The octahedral complexes [Cr(dmpe)(2)(CN)X](+) (dmpe = 1,2-bis(dimethylphosphino)ethane, X = Cl, Br, I) and Cr(dmpe)(2)(CN)X (X = Cl, I) are synthesized and structurally characterized. Variable-field magnetization measurements show the magnitude of D for these complexes to increase significantly as the halide ligand varies from chloride to iodide, ranging from 0.11 cm(-1) for [Cr(dmpe)(2)(CN)Cl](+) to 6.26 cm(-1) for Cr(dmpe)(2)(CN)I.
The Molecular Networks of Abiotic Stress Signaling (2009)

This chapter contains sections titled: Introduction Abscisic acid The molecular mechanisms of salt tolerance The transcriptional regulation of cold- and drought-inducible genes Oxidative stress management Posttranscriptionl regulation of gene expression Future perspectives 406 References
Ein globaler Blick auf akute Exazerbationen der idiopathischen Lungenfibrose (AE-IPF): Ergebnisse einer internationalen Umfrage (2019)

Hintergrund Die AE-IPF ist eine tödliche Komplikation der IPF. Internationale Leitlinien zur Diagnostik, Therapie und Prävention liegen bisher nicht vor. Ziel der Arbeit war es, globale Unterschiede in Bezug auf die AE-IPF zu ermitteln, um Leitlinien entwickeln zu können.
Alphavirus Mutator Variants Present Host-Specific Defects and Attenuation in Mammalian and Insect Models (2014)

Arboviruses cycle through both vertebrates and invertebrates, which requires them to adapt to disparate hosts while maintaining genetic integrity during genome replication. To study the genetic mechanisms and determinants of these processes, we use chikungunya virus (CHIKV), a re-emerging human pathogen transmitted by the Aedes mosquito. We previously isolated a high fidelity (or antimutator) polymerase variant, C483Y, which had decreased fitness in both mammalian and mosquito hosts, suggesting this residue may be a key molecular determinant. To further investigate effects of position 483 on RNA-dependent RNA-polymerase (RdRp) fidelity, we substituted every amino acid at this position. We isolated novel mutators with decreased replication fidelity and higher mutation frequencies, allowing us to examine the fitness of error-prone arbovirus variants. Although CHIKV mutators displayed no major replication defects in mammalian cell culture, they had reduced specific infectivity and were attenuated in vivo. Unexpectedly, mutator phenotypes were suppressed in mosquito cells and the variants exhibited significant defects in RNA synthesis. Consequently, these replication defects resulted in strong selection for reversion during infection of mosquitoes. Since residue 483 is conserved among alphaviruses, we examined the analogous mutations in Sindbis virus (SINV), which also reduced polymerase fidelity and generated replication defects in mosquito cells. However, replication defects were mosquito cell-specific and were not observed in Drosophila S2 cells, allowing us to evaluate the potential attenuation of mutators in insect models where pressure for reversion was absent. Indeed, the SINV mutator variant was attenuated in fruit flies. These findings confirm that residue 483 is a determinant regulating alphavirus polymerase fidelity and demonstrate proof of principle that arboviruses can be attenuated in mammalian and insect hosts by reducing fidelity.
The Complex Role of Neutrophils in Tumor Angiogenesis and Metastasis (2016)

Chronic inflammation fosters cancer development and progression and also modulates tumor responses to anticancer therapies. Neutrophils are key effector cells in innate immunity and are known to play a critical role in various inflammatory disorders. However, the functions of neutrophils in cancer pathogenesis have been largely neglected until recently and still remain poorly characterized compared with other immune cells in the tumor microenvironment. We highlight recent findings on the mechanisms by which tumor cells, in cooperation with tumor-associated stromal cells, induce expansion, recruitment, and polarization of neutrophils. We also review the multifaceted roles that neutrophils play in different aspects of cancer development and progression, with an emphasis on tumor angiogenesis and metastasis.
Observations of the cold wake of Typhoon Fanapi (2010) (2013)

Several tens of thousands of temperature profiles are used to investigate the thermal evolution of the cold wake of Typhoon Fanapi, 2010. Typhoon Fanapi formed a cold wake in the Western North Pacific Ocean on 18 September characterized by a mixed layer that was &gt;2.5 °C cooler than the surrounding water, and extending to &gt;80 m, twice as deep as the preexisting mixed layer. The initial cold wake became capped after 4 days as a warm, thin surface layer formed. The thickness of the capped wake, defined as the 26 °C–27 °C layer, decreased, approaching the background thickness of this layer with an e‐folding time of 23 days, almost twice the e‐folding lifetime of the Sea Surface Temperature (SST) cold wake (12 days). The wake was advected several hundreds of kilometers from the storm track by a preexisting mesoscale eddy. The observations reveal new intricacies of cold wake evolution and demonstrate the challenges of describing the thermal structure of the upper ocean using sea surface information alone.
The incidence of acute kidney injury in patients with traumatic brain injury (2010)

There is limited information on the incidence of acute kidney injury (AKI) in patients with traumatic brain injury (TBI) although AKI may contribute to morbidity and mortality. We investigated the incidence of AKI in patients with moderate and severe TBI and the association of AKI with risk factors and outcomes in these patients. We studied all TBI patients over 16 years of age admitted to the two designated trauma hospitals in the state of Victoria, Australia from 1 January to 31 December 2008. Patients were included if they had head trauma and presented with a Glasgow coma scale (GCS) <13. Prospectively collected data from the hospital trauma registries, ICUs, and pathology databases were analyzed retrospectively. Risk injury failure loss end (RIFLE) criteria were used to categorize renal function. The incidence of AKI was 9.2% (19/207). Patients who developed AKI were older, had higher severity of illness scores, and a lower GCS. Overall 42.1% of these patients died in hospital compared with 18.1% in patients without AKI. In univariable linear regression analysis, age, severity of illness, and admitting hospital were associated with AKI. After multivariable logistic regression, the occurrence of AKI was associated with age (p < 0.001) and higher APACHE III scores (p = 0.016). AKI is relatively common even in patients with TBI. Its association with age and APACHE III scores helps identify patients at higher risk of AKI.
Métrologie de l’état de polarisation dans le grain de speckle diffusé par une surface rugueuse (2013)

National audience
Hepatocarcinogenesis in non‐cirrhotic liver is associated with a reduced number of clonal hepatocellular patches in non‐tumorous liver parenchyma (2012)

Abstract We investigated circumscribed cell proliferations in healthy livers in comparison to non‐cirrhotic livers bearing hepatocellular carcinoma. Using histochemical staining for cytochrome c oxidase, the fourth complex of the respiratory chain, we visualized patch‐forming descendents of regeneratively active liver cells. The clonal nature of these patches was verified by laser‐capture microdissection and Sanger sequencing of the enzyme's core subunits in patches carrying marker mutations on the mtDNA. We demonstrate a highly significant increase of the patch size and also a highly significant increase in the number of patches carrying marker mutations between hepatocellular carcinoma‐free and ‐bearing livers. Thus, the carcinoma‐bearing livers accumulated more genetic damage on mtDNA than the control group. Furthermore, for the first time, we present evidence in hepatocellular carcinoma‐bearing non‐cirrhotic livers of a significantly reduced pool of regeneratively active liver cells that are genetically and functionally altered. The analogy to ageing‐related changes is suggestive of premature ageing of stem cells in non‐cirrhotic hepatocellular carcinoma‐bearing liver as an early step to hepatocarcinogenesis. Copyright © 2012 Pathological Society of Great Britain and Ireland. Published by John Wiley &amp; Sons, Ltd.
Insight into the 3D Architecture and Quasicrystal Symmetry of Multilayer Nanorod Assemblies from Moiré Interference Patterns (2012)

Vertical nanorod assembly over three dimensions is shown to result in the formation of Moiré interference patterns arising from rotational offsets between respective monolayer sheets. Six distinct patterns are observed in HRTEM and angular dark-field STEM (DF-STEM) images, allowing the exact angle of rotation to be determined from their respective size and repeat order. At large rotation angles approaching 30°, the aperiodicity in the structure of the nanorod supercrystals becomes apparent, resulting in 12-fold ordering characteristics of a quasicrystal. The rotational offsets are further elucidated from Fourier transform and small angle electron diffraction, allowing interpretation of several multilayers when combined with DF-STEM and SEM. Pattern formation owing to angular rotation is differentiated from those occurring from a lateral shift, providing an important insight into the complex multilayered structures in assembled rods that may have an impact on their collective electronic or photonic properties. We also show how random tetrapods when present at low concentrations in colloidal nanorod solutions act as termination points for 2D sheet crystallization, impacting the size and shape of the resultant assemblies. The occurrence of Moiré patterns in rod assemblies demonstrates the extraordinary order achievable in their assembly and offers a nondestructive technique to precisely map the placement of each nanorod in this important nanoarchitecture.
TORNADO1 and TORNADO2 are required for the specification of radial and circumferential pattern in the Arabidopsis root (2000)

The cell layers of the Arabidopsis primary root are arranged in a simple radial pattern. The outermost layer is the lateral root cap and lies outside the epidermis that surrounds the ground tissue. The files of epidermal and lateral root cap cells converge on a ring of initials (lateral root cap/epidermis initial) from which the epidermal and lateral root cap tissues of the seedling are derived, once root growth is initiated after germination. Each initial gives rise to a clone of epidermal cells and a clone of lateral root cap cells. These initial divisions in the epidermal/lateral root cap initial are defective in tornado1 (trn1) and trn2 plants indicating a requirement for TRN1 and TRN2 for initial cell function. Furthermore, lateral root cap cells develop in the epidermal position in trn1 and trn2 roots indicating that TRN1 and TRN2 are required for the maintenance of the radial pattern of cell specification in the root. The death of these ectopic lateral root cap cells in the elongation zone (where lateral root cap cells normally die) results in the development of gaps in the epidermis. These observations indicate that TRN1 and TRN2 are required to maintain the distinction between the lateral root cap and epidermis and suggest that lateral root cap fate is the default state. It also suggests that TRN1 and TRN2 repress lateral root cap fate in cells in the epidermal location. Furthermore, the position-dependent pattern of root hair and non-root hair cell differentiation in the epidermis is defective in trn1 and trn2 mutants. Together these results indicate that TRN1 and TRN2 are required for the maintenance of both the radial pattern of tissue differentiation in the root and for the subsequent circumferential pattern within the epidermis.
Simulation for Deployment of an Inflatable Disk in Orbit (2000)

Covers advancements in spacecraft and tactical and strategic missile systems, including subsystem design and application, mission design and analysis, materials and structures, developments in space sciences, space processing and manufacturing, space operations, and applications of space technologies to other fields.
Experiments on Transformation Thermodynamics: Molding the Flow of Heat (2013)

It was recently shown theoretically that the time-dependent heat conduction equation is form invariant under curvilinear coordinate transformations. Thus, in analogy to transformation optics, fictitious transformed space can be mapped onto (meta)materials with spatially inhomogeneous and anisotropic heat-conductivity tensors in the laboratory space. On this basis, we design, fabricate, and characterize a microstructured thermal cloak that molds the flow of heat around an object in a metal plate. This allows for transient protection of the object from heating while maintaining the same downstream heat flow as without object and cloak.
Free fatty acids induce ER stress and block antiviral activity of interferon alpha against hepatitis C virus in cell culture (2012)

These results suggest that intracellular fat accumulation in HCV cell culture induces ER stress, defective Jak-Stat signaling, and attenuates the antiviral response, thus providing an explanation to the clinical observation regarding how hepatocellular steatosis influences IFN-α response in CHC.
Optimal Skin-to-Stone Distance Is a Positive Predictor for Successful Outcomes in Upper Ureter Calculi following Extracorporeal Shock Wave Lithotripsy: A Bayesian Model Averaging Approach (2015)

Our data indicate that a group 2 SSD of approximately 10 cm is a positive predictor for success following ESWL.
Preoperative Mapping of the Sensorimotor Cortex: Comparative Assessment of Task-Based and Resting-State fMRI (2014)

Resting state fMRI (rs-fMRI) has recently been considered as a possible complement or alternative to task-based fMRI (tb-fMRI) for presurgical mapping. However, evidence of its usefulness remains scant, because existing studies have investigated relatively small samples and focused primarily on qualitative evaluation. The aim of this study is to investigate the clinical usefulness of rs-fMRI in the context of presurgical mapping of motor functions, and in particular to determine the degree of correspondence with tb-fMRI which, while not a gold-standard, is commonly used in preoperative setting. A group of 13 patients with lesions close to the sensorimotor cortex underwent rs-fMRI and tb-fMRI to localize the hand, foot and mouth motor areas. We assessed quantitatively the degree of correspondence between multiple rs-fMRI analyses (independent-component and seed-based analyses) and tb-fMRI, with reference to sensitivity and specificity of rs-fMRI with respect to tb-fMRI, and centre-of-mass distances. Agreement with electro-cortical stimulation (ECS) was also investigated, and a traditional map thresholding approach based on agreement between two experienced operators was compared to an automatic threshold determination method. Rs-fMRI can localize the sensorimotor cortex successfully, providing anatomical specificity for hand, foot and mouth motor subregions, in particular with seed-based analyses. Agreement with tb-fMRI was only partial and rs-fMRI tended to provide larger patterns of correlated activity. With respect to the ECS data available, rs-fMRI and tb-fMRI performed comparably, even though the shortest distance to stimulation points was observed for the latter. Notably, the results of both were on the whole robust to thresholding procedure. Localization performed by rs-fMRI is not equivalent to tb-fMRI, hence rs-fMRI cannot be considered as an outright replacement for tb-fMRI. Nevertheless, since there is significant agreement between the two techniques, rs-fMRI can be considered with caution as a potential alternative to tb-fMRI when patients are unable to perform the task.