Oral Phentolamine in Nonspecific Erectile Insufficiency (1988)

Brief Reports15 July 1988Oral Phentolamine in Nonspecific Erectile InsufficiencyGrant Gwinup, MDGrant Gwinup, MDSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-109-2-162 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn patients with erectile insufficiency, it is often difficult to find a definite cause for the problem when clinical vascular disease, neurologic deficiency, obvious psychological problems, and endocrine abnormalities, including diabetes, have been excluded. Such patients are usually categorized as suffering from non-specific erectile insufficiency. A major addition to the literature on treating erectile insufficiency was the finding that intercavernosal injection of vasoactive substances often produces a dramatic effect in patients with non-specific erectile insufficiency, as well as in those whose disease was suspected to have a more precise cause (1-2). The injection technique, however, is inconvenient and has produced...References1. Brindley G. Maintenance treatment of erectile impotence by cavernosal unstriated muscle relaxant injection. Br J Psychiatry. 1986;149:210-5. CrossrefMedlineGoogle Scholar2. Janosko E. Intracavernous self-injection of papaverine and regitine for the treatment of organic impotence. NC Med J. 1986;47:305-7. MedlineGoogle Scholar3. MoralesSurridgeMarshallFenemore ADPJ. Nonhormonal pharmacological treatment of organic impotence. J Urol. 1982;128:45-7. CrossrefMedlineGoogle Scholar4. Brindley G. Cavernosal alpha-blockade: a new technique for investigating and treating erectile impotence. Br J Psychiatry. 1983; 143:332. CrossrefMedlineGoogle Scholar5. Fleiss J. Statistical methods for rates and proportions. 2nd ed. New York: John Wiley & Sons; 1981:117-9. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: From the University of California, Irvine, Medical Center, Orange, California. For the current author address, see end of text. 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