gebhart/patrepeval huggingface dataset:
Poly(4-(aminomethyl)styrene)-b-polystyrene:  Synthesis and Unilamellar Vesicle Formation (2002)

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTPoly(4-(aminomethyl)styrene)-b-polystyrene: Synthesis and Unilamellar Vesicle FormationStefanie M. Gravano, Mark Borden, Timothy von Werne, Edward M. Doerffler, Georgina Salazar, Aaron Chen, Edward Kisak, Joseph A. Zasadzinski, Timothy E. Patten, and Marjorie L. LongoView Author Information Department of Chemistry, University of California, Davis, California 95616-5295, Department of Chemical Engineering and Materials Science, University of California, Davis, California 95616, and Department of Chemical Engineering, University of California, Santa Barbara, California 93106 Cite this: Langmuir 2002, 18, 5, 1938–1941Publication Date (Web):February 8, 2002Publication History Received16 August 2001Revised19 November 2001Published online8 February 2002Published inissue 1 March 2002https://pubs.acs.org/doi/10.1021/la011309ehttps://doi.org/10.1021/la011309ebrief-reportACS PublicationsCopyright © 2002 American Chemical SocietyRequest reuse permissionsArticle Views887Altmetric-Citations32LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Copolymers,Lipids,Micelles,Vesicle formation,Vesicles Get e-Alerts
A self determinant recognizing T cell hybridoma. (1982)

A T cell hybridoma (53(113)) obtained by fusion of BALB/c spleen cells and the BW 5147 lymphoma T cell line is described. This hybridoma recognizes mouse RBC (MRBC) and rat RBC, but not human, rabbit, guinea pig, or SRBC. The culture supernatant possesses hemagglutinating activity for the same indicator RBC. In addition to this, 53(113) cells are able to form protein A plaques in the presence of guinea pig complement and normal mouse serum (NMS) or purified mouse immunoglobulins (Ig). Because mouse Ig as well as sonicates from MRBC are able to inhibit the rosettes between the hybridoma cells and the MRBC, and because the sonicates inhibit protein A plaque formation, it seems likely that the same product can recognize a similar determinant expressed on MRBC and mouse Ig. The hypothesis that a 53(113) structure recognizes identical or cross-reactive carbohydrate determinants shared by murine Ig and C is considered.
Untersuchungen zum Einfluss Seltener Erd-Citrate auf Leistungsparameter beim Schwein und die ruminale Fermentation im künstlichen Pansen (RUSITEC) (2004)

Investigations on the effects of Rare earth Element Citrates on growth promoting parameters in pigs and on ruminal fermentation in an artificial rumen (RUSITEC)

For decades Rare Earth Elements, such as lanthanum, cerium, and praseodymium have been used in Chinese agriculture and farming for yield increase and growth promoting effects. Many Chinese studies showed partly enormous growth promoting effects whereas the most spectacular is seen in poultry and pig production.
Several feeding trials with Rare Earth Elements were already carried out in our working group. So far mineral salt chlorides were used in previous studies. In the present study we tested for the first time the effects of Rare Earth Elements Citrate in grower pigs as well as in an in vitro trial in ruminants.
A feeding study with 28 piglets (German Landrace x Pietrain) was carried out. They were separated in 4 dietary groups, each containing 7 animals. These animals received a regular diet, supplemented with a mixture of Rare Earth Elements Citrate in concentrations of 0, 50, 100, and 200 mg/kg feed for a 6 week period. A positive effect of the Rare Earth Elements Citrate on fattening performance parameters was determined. In the trial period the daily body weight gain of the two high supplemented groups increased between 8.6 % to 22.6 % compared to the control group. The low dosage group showed no difference. An increase in the feed conversion rate from 2 % to 6 % was shown in all Rare Earth Elements supplemented groups. This indicates that within the pig feeding highly increased growth-promoting effects were determined when supplemented with Rare Earth Elements Citrate compared with the studies in which the chloride form was used.
The study on possible effects of Rare Earth Elements in ruminal fermentation was carried out with the Rumen Simulation Technique (RUSITEC), an artificial rumen. The effect of Rare Earth Elements in different dosages was compared to a negative control (without supplement) and a positive control (Tetracycline). Each trial lasted for a period of 10 days. The influence on the parameters pH-value, NH3, redox potential, fatty acid pattern, and gas production was analysed. Since the ruminal fermentation was not influenced, the conclusion can be drawn, that in this respect microorganisms are not affected by Rare Earth Elements.
Masking of the Fc region in human IgG4 by constrained X-ray scattering modelling: implications for antibody function and therapy (2010)

Of the four human IgG antibody subclasses IgG1-IgG4, IgG4 is of interest in that it does not activate complement and exhibits atypical self-association, including the formation of bispecific antibodies. The solution structures of antibodies are critical to understand function and therapeutic applications. Thus IgG4 was studied by synchrotron X-ray scattering. The Guinier X-ray radius of gyration R(G) increased from 5.0 nm to 5.1 nm with an increase of concentration. The distance distribution function P(r) revealed a single peak at 0.3 mg/ml, which resolved into two peaks that shifted to smaller r values at 1.3 mg/ml, even though the maximum dimension of IgG4 was unchanged at 17 nm. This indicated a small concentration dependence of the IgG4 solution structure. By analytical ultracentrifugation, no concentration dependence in the sedimentation coefficient of 6.4 S was observed. Constrained scattering modelling resulted in solution structural determinations that showed that IgG4 has an asymmetric solution structure in which one Fab-Fc pair is closer together than the other pair, and the accessibility of one side of the Fc region is masked by the Fab regions. The averaged distances between the two Fab-Fc pairs change by 1-2 nm with the change in IgG4 concentration. The averaged conformation of the Fab regions appear able to hinder complement C1q binding to the Fc region and the self-association of IgG4 through the Fc region. The present results clarify IgG4 function and provide a starting point to investigate antibody stability.
Free perforation of the small intestine in collagenous sprue (2009)

A 67-year-old man with celiac disease developed recurrent diarrhea, profound weakness and weight loss, with evidence of marked protein depletion. His clinical course was refractory to a strict gluten-free diet and steroid therapy. Postmortem studies led to definition of unrecognized collagenous sprue that caused ulceration and small intestinal perforation. Although PCR showed identical monoclonal T-cell populations in antemortem duodenal biopsies and postmortem jejunum, careful pathological evaluation demonstrated no frank lymphoma. Rarely, overt or even cryptic T-cell lymphoma may complicate collagenous sprue, however, small intestinal ulcers and perforation may also develop independently. The dramatic findings here may reflect an underlying or early molecular event in the eventual clinical appearance of overt T-cell lymphoma.
Blood kinetics and in vivo chemotaxis of transfused neutrophils: effect of colllection method, donor corticosteroid treatment, and short-term storage (1979)

To evaluate effect of collection technique and short-term storage on in vivo cell function, neutrophils were collected from 53 normal subjects by phlebotomy (PB), intermittent flow centrifugation (IFC), or filtration leukopheresis (FL), stored 0 or 1 day, labeled with 32P-diisopropylfluorophosphate, reinfused into the donor, and blood kinetics and/or skin chamber accumulation of labeled cells measured. The blood kinetics of unstored PB and IFC cells were similar; the kinetics of unstored FL cells were markedly abnormal. The percent of infused neutrophils localizing to the skin chamber was 0.1, 0.06, and 0.006 for unstored PB, IFC, and FL cells, respectively. One-day storage substantially decreased chamber accumulation of infused neutrophils. Donor steroid pretreatment had no effect on chamber results. Thus, in vivo chemotactic ability of IFC neutrophils is slightly impaired, whereas that of FL cells is severely impaired. One-day storage of either cell concentrate causes further cell damage.
Globalization and Competitiveness (2013)

This book evaluates the evolution of 'Big Business in Asia', as we enter the new millennium. It focuses on recent issues affecting large corporations, both indigenous and foreign owned, such as multinational companies and international joint ventures, as well as on key events such as the Asian Crisis and its aftermath, China's entry into the WTO, the recent downturn in the world economy and the onset of SARS. A special issue of the journal Asia Pacific Business Review.
Voice control of remote stereoscopic systems (2002)

The voice control of a stereoscopic system for control of a remote vehicle is discussed. Voice control was accomplished by the integration of a Votan voice recognition system into the main stream of the control circuitry. The camera platform, display console, and voice control details are given. The way that commands generated by an operator are sent to the camera platform is described. The primary advantage of this feature was the reduction of the number of personnel required to control the remote vehicle by freeing the hands of at least one operator.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
An Initial Study of the Fundamentals of Ice Crystal Icing Physics in the NASA Propulsion Systems Laboratory (2017)

This paper presents results from an initial study of the fundamental physics of ice-crystal ice accretion using the NASA Propulsion Systems Lab (PSL). Ice accretion due to the ingestion of ice-crystals is being attributed to numerous jet-engine power-loss events. The NASA PSL is an altitude jet-engine test facility which has recently added a capability to inject ice particles into the flow. NASA is evaluating whether this facility, in addition to full-engine and motor-driven-rig tests, can be used for more fundamental ice-accretion studies that simulate the different mixed-phase icing conditions along the core flow passage of a turbo-fan engine compressor. The data from such fundamental accretion tests will be used to help develop and validate models of the accretion process. The present study utilized a NACA0012 airfoil. The mixed-phase conditions were generated by partially freezing the liquid-water droplets ejected from the spray bars. This paper presents data regarding (1) the freeze out characteristics of the cloud, (2) changes in aerothermal conditions due to the presence of the cloud, and (3) the ice accretion characteristics observed on the airfoil model. The primary variable in this test was the PSL plenum humidity which was systematically varied for two duct-exit-plane velocities (85 and 135 ms) as well as two particle size clouds (15 and 50 m MVDi). The observed clouds ranged from fully glaciated to fully liquid, where the liquid clouds were at least partially supercooled. The air total temperature decreased at the test section when the cloud was activated due to evaporation. The ice accretions observed ranged from sharp arrow-like accretions, characteristic of ice-crystal erosion, to cases with double-horn shapes, characteristic of supercooled water accretions.
Accurate Power-Efficient Format-Scalable Multi-Parallel Optical Digital-to-Analogue Conversion (2021)

In optical transmitters generating multi-level constellations, optical modulators are preceded by Electronic Digital-to-Analog-Converters (eDAC). It is advantageous to use eDAC-free Optical Analog to Digital Converters (oDAC) to directly convert digital bitstreams into multilevel PAM/QAM optical signals. State-of-the-art oDACs are based on Segmented Mach-Zehnder-Modulators (SEMZM) using multiple modulation segments strung along the MZM waveguides to serially accumulate binary-modulated optical phases. Here we aim to assess performance limits of the Serial oDACs (SEMZM) and introduce an alternative improved Multi-Parallel oDAC (MPoDAC) architecture, in particular based on arraying multiple binary-driven MZMs in parallel: Multi-parallel MZM (MPMZM) oDAC. We develop generic methodologies of oDAC specification and optimization encompassing both SEMZM and MPMZM options in Direct-Detection (DD) and Coherent-Detection (COH) implementations. We quantify and compare intrinsic performance limits of the various serial/parallel DD/COH subclasses for general constellation orders, comparing with the scant prior-work on the multi-parallel option. A key finding: COH-MPMZM is the only class synthesizing ‘perfect’ (equi-spaced max-full-scale) constellations while maximizing energy-efficiency-SEMZM/MPMZM for DD are less accurate when maximal energy-efficiency is required. In particular, we introduce multiple variants of PAM4|8 DD and QAM16|64 COH MPMZMs, working out their accuracy vs. energy-efficiency-and-complexity tradeoffs, establishing their format-reconfigurability (format-flexible switching of constellation order and/or DD/COH).
Deterministic Switching of Hierarchy during Wrinkling in Quasi-Planar Bilayers (2016)

Emergence of hierarchy during compression of quasi-planar bilayers is preceded by a mode-locked state during which the quasi-planar form persists. Transition to hierarchy is determined entirely by geometrically observable parameters. This results in a universal transition phase diagram that enables one to deterministically tune hierarchy even with limited knowledge about material properties.
Cross-talk between endothelial and tumor cells via basic fibroblast growth factor and vascular endothelial growth factor signaling promotes lung cancer growth and angiogenesis (2015)

The present study aimed to investigate the origin and potential mechanisms of angiogenesis in lung cancer cells. Normal endothelial cells (ECs) were isolated from human umbilical vein ECs (HUVECs) and cultured. The human lung cancer A549 cell line was also used. The cross-talk model between the HUVECs and the A549 cell line was constructed <i>in vitro</i> using a Millicell co-culture system. Cluster of differentiation (CD)31 and CD146 were selected as markers of the HUVECs. CD105 was used as a marker of activated blood vessel ECs in the tumor microenvironment and glucose-regulated protein-78 (GRP-78) was used as a biomarker of the A549 cells. The four markers were detected by immunofluorescence, and the mean optical density was calculated. The growth curves were constructed using the cell proliferation reagent, WST-1. The expression of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) in the media was measured using an ELISA. The average proliferation rates of the co-cultured HUVECs and A549 cells were significantly higher than those observed in the control groups. The fluorescence intensity of CD105 expression in the co-cultured HUVECs was higher than that in the control group. The fluorescence intensity of GRP-78 in the co-cultured A549 cells was higher than that in the A549 cells cultured alone. The average expression levels of VEGF and bFGF in the co-cultured model were higher than in the control groups. Therefore, it was hypothesized that cancer cells may induce the differentiation of normal ECs into vascular ECs via the secretion of VEGF and bFGF. Furthermore, vascular ECs can affect the proliferation and differentiation of cancer cells.
Printing-induced cell injury evaluation during laser printing of 3T3 mouse fibroblasts (2017)

Three-dimensional bioprinting has emerged as a promising solution for the freeform fabrication of living cellular constructs, which can be used for tissue/organ transplantation and tissue models. During bioprinting, some living cells are unavoidably injured and may become necrotic or apoptotic cells. This study aims to investigate the printing-induced cell injury and evaluates injury types of post-printing cells using the annexin V/7-aminoactinomycin D and FAM-DEVD-FMK/propidium iodide assays during laser printing of NIH 3T3 mouse fibroblasts. As observed, the percentage of post-printing early apoptotic mouse fibroblasts increases with the incubation time, indicating that post-printing apoptotic mouse fibroblasts have different initiation lag times of apoptosis due to different levels of mechanical stress exerted during laser printing. Post-printing necrotic mouse fibroblasts can be detected immediately after printing, while post-printing early apoptotic mouse fibroblasts need time to develop into a late apoptotic stage. The minimum time needed for post-printing early apoptotic mouse fibroblasts to complete their apoptosis pathway and transition into late apoptotic mouse fibroblasts is from 4 h to 5 h post-printing. The resulting knowledge of the evolution of different apoptotic post-printing mouse fibroblasts will help better design future experiments to quantitatively determine, model, and mitigate the post-printing cell injury based on molecular signal pathway modeling.
Synthesis of methyl orange in a micro reactor (2012)

Summary Methyl orange is an orange chemical substance which can be used as a pH-indicator. The synthesis of methyl orange occurs through diazotization. The best ratio we found for creating methyl orange was 2:2:1 for the solutions A, B and C we used. Lower flow rates also resulted in a higher production of methyl orange. Because we only tried ratios of two to one, there could be an even more efficient ratio we didn’t find.
Evidenzbasierte Analyse zum Nutzen eines Navigationssystemes bei Nasen und Nasennebenhöhleneingriffen (2016)

Einleitung: Evidenzbasierte Analysen zum tatsächlich resultierenden Nutzen der Navigationstechnologie sind bislang nur in Teilaspekten vorhanden. Methoden: In der vorliegenden Studie wurden daher Patienten mit chronischer Polyposis der NNH untersucht. Gruppe A: OP unter Navigation. Gruppe B: Eingriff primär konventionell mit abschließender Navigations-Kontrolle. Gruppe C: CT nach konventioneller NNH-Intervention. Alle Gruppen waren hinsichtlich Alter, Geschlecht und Krankengeschichte vergleichbar. Es erfolgte die Erfassung des subjektiven Nutzens des Navigationssystems durch die Operateure sowie des zeitlichen Mehraufwandes und der Grad der Residualpathologie nach OP. Die Ergebnisse könnten zum Teil mittels CT/DVT nachuntersucht werden. Ergebnis: Insbesondere in Gruppe B wurde die postoperative Navigationskontrolle als wertvoll bewertet. Die Narkosedauer verlängerte sich nur um durchschnittlich 10 min. Bei identischer Ausgangssituation in allen drei Gruppen (freie, teilverschattete und totalverschattete Nebenhöhlen) wurde nur durch Einsatz der Navigationsassistenz eine durchschnittlich 96%ige Resektion erreicht; bei konventionellem Vorgehen verblieben dagegen ~40% Residualpathologien. Besonders deutlich zeigte sich dies im Bereich der Kieferhöhlen und des vorderen Siebbeins. Zusammenfassung: Der Einsatz der intraoperativen Navigation bei chronischer Sinusitis bietet objektivierbare Vorteile: Der zeitliche Mehraufwand von wenigen Minuten pro Eingriff ist dadurch vertretbar, dass krankhaft veränderte Schleimhaut besonders in problematischen Subregionen des Nasennebenhöhlensystems deutlich umfassender lokalisiert und entfernt werden kann. Dies ist ein klinisch wichtiger Aspekt aufgrund der hohen Rezidivrate der Erkrankung. Der Erstautor gibt keinen Interessenkonflikt an.
Heat Transfer Characteristics in Flue Gas Fired Regenerators of Water/Lithium Bromide Absorption Chillers (2006)

It has already been shown that efficiency of direct-fired absorption chillers or tri-generation systems (CCHP) can be increased if the hot flue gas - from internal gas burner or from motor engines or gas turbines - is successively utilized in the absorption cycle at several temperature levels. For successful realization of such concepts, however, efficient heat exchanger designs are required. An increase in complexity on the flue gas side of the chiller must not introduce a proportional increase in size, cost, and pressure drop. Thus, the development of a compact and efficient flue gas fired regenerator design with low flue gas pressure drop is a major step towards COP increase in direct-fired and exhaust-fired absorption chillers. The potential of different regenerator concepts including common smoke tube design and alternative boiling tube designs with natural circulation of the lithium bromide solution and flue gas flow across bundles of plain or finned tubes is discussed. Promising designs are identified on basis of numerical calculations. A semi-industrial sized prototype of a direct-fired regenerator with consecutive sections of plain and finned vertical boiling tubes has been tested in laboratory over a range of thermal inputs up to 256 kW (net. CV). Experimental results of heat transfer and combustion side pressure drop investigations at the novel regenerator are presented. Accordance of experimental results with theoretical predictions is shown.
Dielectric properties of conductively loaded polyimides in the far infrared (2018)

The dielectric properties of selected conductively-loaded polyimide samples are characterized in microwave through far infrared wavebands. These materials, belonging to the Vespel® family, are more readily formed by direct machining than their ceramic loaded epoxy counterparts and present an interesting solution for realizing absorptive optical control structures. Measurements spanning a spectral range from 1 to 600 cm−1 (0.03 to 18 THz) were preformed and used in parametrization of the media’s dielectric function at frequencies below ≈ 3 THz.