gebhart/patrepeval huggingface dataset:
Towards open government through open source software for web analytics: The case of Matomo (2021)

Web analytics technologies provide opportunities for organisations to obtain information about users visiting their websites in order to understand and optimise web usage. Use of such technologies often leads to issues related to data privacy and potential lock-in to specific suppliers and proprietary technologies. Use of open source software (OSS) for web analytics can create conditions for avoiding issues related to data privacy and lock-in, and thereby provides opportunities for a long-term sustainable solution for organisations both in the public and private sectors. The paper characterises use of and engagement with OSS projects for web analytics. Specifically, we contribute a characterisation of use of OSS licensed web analytics technologies in Swedish government authorities, and a characterisation of organisational engagement with the Matomo OSS project for web analytics.
Effective breaking of the action-reaction principle using spatial solitons (2019)

We discuss a class of interactions between self-confined optical beams breaking the action-reaction principle. The effective force intertwining the beams does not satisfy momentum conservation, paving the way to the potential existence of situations where both beams are pushed in the same direction, in turn leading to the so-called diametric drive. In our theoretical proposal the interaction between the two light beams is enabled by optical nonlinearity. The nonlinearity is assumed to change sign with the light polarization, in turn allowing the two light beams to be attracted or repelled by an inhomogeneous region according to the photon polarization. We demonstrate that this exotic type of nonlinear spin-orbit-like interaction can be achieved in nematic liquid crystals (NLCs). In fact, depending on the input polarization, in NLCs a change in temperature corresponds to a focusing or defocusing index change. For the polarization seeing a thermal defocusing response (corresponding to the extraordinary component), the self-confinement is ensured by the simultaneous action of reorientational nonlinearity.
Effect of Electromagnetic Field on Wear Resistance of Fe901/Al2O3 Metal Matrix Composite Coating Prepared by Laser Cladding (2022)

Fe901/Al<sub>2</sub>O<sub>3</sub> metal matrix composite (MMC) coatings were deposited on the surface of 45 steel via electromagnetic field (EF)-assisted laser cladding technology. The influences of EF on the microstructure, phase composition, microhardness, and wear resistance of the Fe901/Al<sub>2</sub>O<sub>3</sub> MMC coating were investigated. The generated Lorentz force (F<sub>L</sub>) and Joule heating due to the application of EF had a positive effect on wear resistance. The results showed that F<sub>L</sub> broke up the columnar dendrites. Joule heating produced more nuclei, resulting in the formation of fine columnar dendrites, equiaxed dendrites, and cells. The EF affected the content of hard phase in the coatings while it did not change the phase composition of the coating, because the coatings with and without EF assistance contained (Fe, Cr), (Fe, Cr)<sub>7</sub>C<sub>3</sub>, Fe<sub>3</sub>Al, and (Al, Fe)<sub>4</sub>Cr phases. The microhardness under 20 mT increased by 84.5 HV<sub>0.2</sub> compared to the coating without EF due to the refinement of grains and the increased content of hard phase. Additionally, the main wear mechanism switched from adhesive wear to abrasive wear.
The problem with the SURF scheme (2017)

There is a serious problem with one of the assumptions made in the security proof of the SURF scheme. This problem turns out to be easy in the regime of parameters needed for the SURF scheme to work. We give afterwards the old version of the paper for the reader's convenience.
Dielectric frequency response measurement as a tool for troubleshooting insulation power factor problems (2003)

This paper presents a new method of evaluating the dielectric frequency response (DFR) test for troubleshooting and identifying the cause of high or unusual insulation power factor test results. The method involves preparing a dielectric frequency response signature (DFRS) from the DFR test on a transformer. The signature of the measured response is then compared with a modeled response of a transformer with a "normal" insulation structure and a library of signatures of known defects. Based on this comparison, it is possible to diagnose power factor defects in the insulation structure of the transformer under test.
Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation (2010)

Focal adhesions (FAs) are mechanosensitive adhesion and signaling complexes that grow and change composition in response to myosin II-mediated cytoskeletal tension in a process known as FA maturation. To understand tension-mediated FA maturation, we sought to identify proteins that are recruited to FAs in a myosin II-dependent manner and to examine the mechanism for their myosin II-sensitive FA association. We find that FA recruitment of both the cytoskeletal adapter protein vinculin and the tyrosine kinase FA kinase (FAK) are myosin II and extracellular matrix (ECM) stiffness dependent. Myosin II activity promotes FAK/Src-mediated phosphorylation of paxillin on tyrosines 31 and 118 and vinculin association with paxillin. We show that phosphomimic mutations of paxillin can specifically induce the recruitment of vinculin to adhesions independent of myosin II activity. These results reveal an important role for paxillin in adhesion mechanosensing via myosin II-mediated FAK phosphorylation of paxillin that promotes vinculin FA recruitment to reinforce the cytoskeletal ECM linkage and drive FA maturation.
ChemInform Abstract: Ring Transformation of 5‐Amino (or Acylamino)‐6‐hydroxy (or benzoyloxy) methylpyrimidin‐4(3H)‐ones into 1H‐Imidazoles. (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Generation of F/sub 0/ contours using a model-constrained data-driven method (2002)

Introduces a model-constrained, data-driven method for generating fundamental frequency contours in Japanese text-to-speech synthesis. In the training phase, the parameters of a command-response F/sub 0/ contour generation model are learned by a prediction module, which can be a neural network or a set of binary regression trees. The input features consist of linguistic information related to accentual phrases that can be automatically derived from text, such as the position of the accentual phrase in the utterance, number of morae, accent type, and parts-of-speech. In the synthesis phase, the prediction module is used to generate appropriate values of model parameters. The use of the parametric model restricts the degrees of freedom of the problem, facilitating data-driven learning. Experimental results show that the method makes it possible to generate quite natural F/sub 0/ contours with a relatively small training database.
ChemInform Abstract: Structure of Potassium Strontium Cuprate, K0.95Sr0.05CuO2. (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Polymerization of ethylene with new diimine complexes of late transition metals (1999)

Three pyridylimine based complexes of NiII and CoII were reacted with methylaluminoxane (MAO) and tested as catalysts in ethylene polymerization. The two nickel catalysts produced mainly methyl branched polymers with good to moderate activity, while the cobalt compound showed only marginal activity. Reaction conditions strongly affect the polymer properties, such as molecular weight, melting temperature, degree of branching, and chain end unsaturation type.
Scalable algorithms and design for debug hardware for test, validation and security of mixed signal/rf circuits and systems (2017)

With the advent of SOCs and SOPs, more functionalities are integrated into an IC or package. Higher level of integration has made testing, validation of ICs more challenging due to lack of observability of internal circuit nodes. This calls for new embedded Design for Test (DFT) circuit design and test methodology development. This work is geared towards solving the analog/RF testing problem mentioned above by crafting intelligent stimulus to excite the non-idealities of the circuit, along with machine learning algorithms to learn the behavior of the system. Though the manufacturing cost of a transistor is decreasing over the technology generations, test cost per transistor is remaining constant or decreasing at a lower rate. So, there will be a time when test cost per transistor will be more than the actual manufacturing cost of a transistor. Every newer technology advancement entails newer test methodologies for keeping the test cost at a certain bound. ATE cost for mixed-signal and RF ICs are higher than that of digital ICs. There is a need in industry for low cost efficient testing, tuning and validation methodologies for mixed-signal and RF circuits and systems. In this thesis, we have addressed the following validation problems:&#13;\ni) Manufacturing testing (Process Adaptive RF Transceiver Testing)&#13;\nii) Post manufacture tuning (Learning Assisted Parallel Testing and Tuning of Massively Beam-forming MIMO systems)&#13;\niii) Pre and post silicon verification (Built In State Consistency Checking for Mixed-Signal/RF Verification)&#13;\nWe have found that the knowledge of DFx design for analog/RF circuits (stimulus design, sensor design) can be leveraged in other emerging security solutions also. For example, in Trojan detection in digital systems and in designing Physically Unclonable Functions (PUFs).
Framework for Design Validation of Security Architectures (2008)

This technical report discusses a framework for design validation of security architectures.
Mechanically Drawn Hydrogels Uniaxially Orient Hydroxyapatite Crystals and Cell Extension (2004)

Freeze−thawed poly(vinyl alcohol) hydrogels were structurally oriented by uniaxial mechanical drawing up to 1−5 times their original length, and the orientation was fixed by successive chemical cross-linking using glutaraldehyde (20 mol %). Hydroxyapatite (HAp) crystals were successfully mineralized onto the oriented hydrogels by repeated alternate immersion into the solutions of phosphate ion and calcium ion. X-ray diffraction images confirmed that the c-axis of the HAp crystal cell was oriented perpendicularly to the surface of the hydrogel. In addition, polarized infrared spectroscopy confirmed the orientation of the phosphate ion. We investigated the effects of these structurally oriented HAp−PVA hydrogel hybrids on the anisotropy of cell extension. Scanning electron microscopy confirmed that mouse fibroblasts (L929) extended onto the oriented HAp−hydrogel hybrid along the drawing direction. These results may lead to the development of a tissue engineering scaffold for yielding oriented bony tissues.
Real-Time Multiple-Vehicle Detection and Tracking System in Complex Environment with Automatic Lane Detection and Reducing Shadow Effects (2011)

In this study, an real-time multiple-vehicle detection and tracking system in complex environments with automatic lane detection and reducing shadow effects is proposed. First, lane marks can be automatically detected, and this automation makes the proposed system more possible to deploy in the practical traffic conditions. Second, Histogram Extension (HE) addresses how to remove the effects of weather and light impact. Next, vehicle detection with Merge Boundary Rectangle Rule (MBRR) is utilized to merge fractions of moving objects which may be candidates of detected vehicles. Finally, traffic parameters are built based on a proper tracking procedure with reducing shadow effects. Experimental results show that the proposed methods are robust, accurate, and powerful to overcome complex weather conditions and traffic jams.
Computation of Misalignment and Primary Mirror Figure Error Parameters of Classical Two-Mirror Telescopes (2010)

It is demonstrated how secondary mirror misalignment parameters and primary mirror astigmatic figure error of two-mirror telescopes can be computed utilizing the nodal properties of coma and astigmatism, while taking into account pointing changes.
Resolving the 3D Nano-architecture of the Actin Cytoskeleton (2020)

Journal Article Resolving the 3D Nano-architecture of the Actin Cytoskeleton Get access James Galbraith, James Galbraith OHSU, Lake Oswego, Oregon, United States Search for other works by this author on: Oxford Academic Google Scholar Jesse Aaron, Jesse Aaron HHMI Janelia Research Campus, Ashburn, Virginia, United States Search for other works by this author on: Oxford Academic Google Scholar Ulrike Boehm, Ulrike Boehm HHMI Janelia Research Campus, Ashburn, Virginia, United States Search for other works by this author on: Oxford Academic Google Scholar Teng-Leong Chew, Teng-Leong Chew HHMI Janelia Research Campus, Ashburn, Virginia, United States Search for other works by this author on: Oxford Academic Google Scholar Catherine Galbraith Catherine Galbraith OHSU, Lake Oswego, Oregon, United States Search for other works by this author on: Oxford Academic Google Scholar Microscopy and Microanalysis, Volume 26, Issue S2, 1 August 2020, Page 1032, https://doi.org/10.1017/S1431927620016736 Published: 01 August 2020
Integrated Resource Management and Scheduling with Multi-Resource Constraints (2005)

Dynamic real-time systems such as phased-array radars must manage multiple resources, satisfy energy constraints and make frequent on-line scheduling decisions. These systems are hard to manage because task and system requirements change rapidly (e.g. in radar systems, the targets/tasks in the sky are moving continuously) and must satisfy a multitude of constraints. Their highly dynamic nature and stringent time constraints lead to complex cross-layer interactions in these systems. Therefore, the design of such systems has long been a conservative and/or unpredictable mixture of pre-computed schedules, pessimistic resource allocations, cautious energy usage and operator intuition. In this paper, we present an integrated approach that simultaneously maximizes overall system utility, performs task scheduling and satisfies multi-resource constraints. Using a phased-array radar system, we show that our approach can reconfigure settings of 100 tracks at every 0.7 sec in real-time, and performs within 0.1% of the achievable optimal solution.
Osteogenic Differentiation of Bone-Marrow-Derived Stem Cells Cultured with Mixed Gelatin and Chitooligosaccharide Scaffolds (2011)

This study investigates the effect of scaffolds prepared from gelatin (G) and chitooligosaccharide (COS) on the osteogenic differentiation of rat bone-marrow-derived mesenchymal stem cells (MSC). The sponge scaffolds at G/COS mixing ratios of 100:0, 70:30 and 50:50 were fabricated by freeze-drying, followed by glutaraldehyde cross-linking. The pore size of the G/COS scaffolds ranged from 70 to 105 μm. MSC cultured in the scaffolds in the osteogenic medium were differentiated into osteogenic cells for all G/COS scaffolds. Calcium nodules were homogeneously formed on the surface of scaffolds cultured with MSC. A Fourier transform infrared (FT-IR) analysis demonstrated the formation of hydroxyapatite spectroscopically. Among all G/COS scaffolds, the highest ALP activity and calcium content were observed for MSC cultured in the G/COS 70:30 scaffolds. The G/COS 70:30 scaffolds were then pre-cultured with MSC in the osteogenic medium for 28 days and subcutaneously implanted into nude mice to evaluate ectopic bone formation. Enhanced vascularization, cell infiltration, collagen formation and calcium deposition around the scaffolds implanted were histologically observed at 2 and 8 weeks after implantation. It was concluded that the G/COS scaffold with the mixing ratio of 70:30 was a promising organic material to induce osteogenic differentiation of MSC.
Rational design of kisspeptin analogs for the control of reproduction (2018)

International audience
Hot-Melt Adhesive Attachment System (1983)

Adhesive system is as effective on Earth as in space. Fiberglass cloth mounted in head assembly. When adhesive reaches melt temperature head is attached to metals composites, ceramics, and other materials. Once attached, head cooled rapidly for quick stick. Used to tether tools or attach temporary scaffolding to walls, buildings, or beams.
On the Chemistry of Iron Oxide Supported on γ-Alumina and Silica Catalysts (2018)

Catalysts of iron oxide on γ-alumina and silica which were prepared by an incipient wetness impregnation technique have been investigated in an effort to understand how the surface chemical properties are influenced by the nature of the supports. Surprisingly, this is the first study to compare in depth the influence of the supports on physicochemical parameters such as acidity, site nuclearity, and reducibility. In this study, surface characterisation techniques including N<sub>2</sub> physisorption at -196 °C, ammonia temperature-programmed desorption, inductively coupled plasma optical emission spectrometry, temperature-programmed reduction with hydrogen, CO-chemisorption, scanning electron microscopy, transmission electron microscopy, and NO adsorption by in situ Fourier transform infrared spectroscopy have been performed to understand the different surface reactions occurring over the two different supports. The aim of this study is to ascertain the primary differences between these two catalysts using several catalyst characterization techniques and correlate their chemical and structural differences to their catalytic activity in the conversion of 2-chlorophenol. The results disclose a higher density of acid sites, a smaller particle size of iron oxide, stabilization of Fe(II) aluminate after reduction on the alumina surface, and finally, the formation of isolated iron cations on the surface of alumina which are notably absent on the silica-supported catalyst.
Influence of thyroidectomy and prolactin suppression on the growth of N-nitrosomethylurea-induced rat mammary carcinomas. (1983)

Mammary carcinomas were induced in female Sprague-Dawley rats with N-nitrosomethylurea. Thyroidectomy increased the serum prolactin and reduced serum growth hormone levels of 17 rats without affecting tumor growth. Pergolide mesylate, 80 micrograms twice daily for 7 days, suppressed the serum prolactin of another 17 animals; seven of 17 tumors continued to grow, four became static, and six (35%) underwent partial regression. Treatment with pergolide mesylate plus thyroidectomy reduced both serum prolactin and growth hormone in all of 14 rats, caused regression of ten of the 14 tumors (71%), while two became static, and two continued to grow. Five of the ten regressions were complete. Only the combined thyroidectomy-pergolide treatment group showed a significant difference in posttreatment surface area compared with the controls (p less than 0.001). Ovine growth hormone, 40 micrograms/hr delivered by s.c. osmotic minipumps for 7 days, stimulated regrowth of six of seven tumors undergoing regression in response to thyroidectomy plus pergolide; the other one became static. Thyroxine, 2 micrograms/100 g body weight, stimulated regrowth of the tumors in another six thyroidectomized rats despite continued suppression of prolactin by pergolide. Thus, regression of N-nitrosomethylurea-induced mammary tumors produced by thyroidectomy plus pergolide is due to the combined suppression of circulating growth hormone and prolactin.
Serine Phosphorylation-Dependent Coregulation of Topoisomerase I by the p14ARF Tumor Suppressor (2007)

p14ARF (ARF) and topoisomerase I play central roles in cancer and have recently been shown to interact. The interaction activates topoisomerase I, an important target for camptothecin-like chemotherapeutic drugs, but the regulation of the interaction is poorly understood. We have used the H358 and H23 lung cancer cell lines and purified recombinant human topoisomerase I to demonstrate that the ARF/topoisomerase I interaction is regulated by topoisomerase I serine phosphorylation, a modification that regulates topoisomerase I activity. Both cell lines express wild-type ARF and topoisomerase I proteins at equivalent levels, but H23 topoisomerase I, unlike that of H358 cells, is largely devoid of serine phosphorylation, has low activity, and complexes poorly with ARF. The ability of H23 topoisomerase I to complex with ARF can be restored by treatment with the serine kinase, casein kinase II. Consistent with these observations, we show that the response of H23 cells to camptothecin treatment is unaffected by changes in intracellular levels of ARF. However, in H358 and PC-3 cells, which express a serine phosphorylated topoisomerase I that complexes with ARF, ectopic overexpression of ARF causes sensitization to camptothecin, and siRNA-mediated down-regulation of endogenous ARF causes desensitization to camptothecin. These biological responses correlate with increased and decreased levels, respectively, of ARF/topoisomerase I complex and DNA-bound topoisomerase I. Thus, ARF is a serine phosphorylation-dependent coregulator of topoisomerase I in vivo, and it regulates cellular sensitivity to camptothecin by interacting with topoisomerase I. Certain cancer associated defects affecting ARF/topoisomerase I complex formation could contribute to cellular resistance to camptothecin.
Self-Assembly of the Binuclear Metal Center of Phosphotriesterase (2000)

The active site of the bacterial phosphotriesterase (PTE) from Pseudomonas diminuta contains two divalent metal ions and a carboxylated lysine residue. The native enzyme contains two Zn(2+) ions, which can be replaced with Co(2+), Cd(2+), Ni(2+), or Mn(2+) without loss of catalytic activity. Carbon dioxide reacts with the side chain of lysine-169 to form a carbamate functional group within the active site, which then serves as a bridging ligand to the two metal ions. The activation of apo-PTE using variable concentrations of divalent metal ions and bicarbonate was measured in order to establish the mechanism by which the active site of PTE is self-assembled. The time courses for the activation of apo-PTE are pseudo-first-order, and the observed rate constants are directly proportional to the concentration of bicarbonate. In contrast, the apparent rate constants for the activation of apo-PTE decrease as the concentrations of the divalent cations are increased and then become constant at higher concentrations of the divalent metal ions. These results are consistent with a largely ordered kinetic mechanism for the assembly of the binuclear metal center where CO(2)/bicarbonate reacts with the apo-PTE prior to the binding of the two metal ions. When apo-PTE is titrated with 0-8 equiv of Co(2+), Cd(2+), or Zn(2+), the concentration of activated enzyme increases linearly until 2 equiv of metal ion is added and then remains constant at elevated levels of the divalent cations. These results are consistent with the synergistic binding of the two metal ions to the active site, and thus the second metal ion binds more tightly to the protein than does the first metal ion. Measurement of the mean dissociation constant indicates that metal binding to the binuclear metal center is strong [(K(alpha)K(beta))(1/2) = 6.0 x 10(-)(11) M and k(off) = 1.5 x 10(-)(3) min(-)(1) for Zn(2+)]. The removal of the carbamate bridge through the mutagenesis of Lys-169 demonstrates that the carbamate bridge is required for both efficient catalysis and overall stability of the metal center.