gebhart/patrepeval huggingface dataset:
<title>Image compression based on multiresolution decomposition: application to chest radiographs</title> (1996)

We have designed an image compression scheme based on multiresolution decomposition using the quadrature mirror filters (QMFs), and applied it to chest radiographs. In order to assess the preservation of diagnostic image quality, we performed image review study using a diagnostic workstation. From the result of review by diagnostic radiologists, our method may be available in clinical practice.
Automated Tolerance Analysis of Mechanical Assemblies from a CAD Model with PMI (2019)

Computer-Aided Design and Applications is an international journal on the applications of CAD and CAM. It publishes papers in the general domain of CAD plus in emerging fields like bio-CAD, nano-CAD, soft-CAD, garment-CAD, PLM, PDM, CAD data mining, CAD and the internet, CAD education, genetic algorithms and CAD engines. The journal is aimed at all developers and users of CAD technology to ptovide CAD solutions for various stages of design and manufacturing. The journal publishes all about Computer-Aided Design and Computer-Aided technologies.
Manipulating composition gradient in cuprate superconducting thin films (2017)

The techniques of growing films with different parameters in single process make it possible to build up a sample library promptly. In this work, with a precisely controlled moving mask, we synthetized superconducting La2-xCexCuO4+/-δ combinatorial films on one SrTiO3 substrate with the doping levels from x = 0.1 to 0.19. The monotonicity in doping along the designed direction is verified by micro-region x-ray diffraction and electric transport measurements. More importantly, by means of numerical simulation, the real change of doping levels is in accordance with a linear gradient variation of doping levels in the La2-xCexCuO4+/-δ combinatorial films. Our results indicate that it is promising to accurately investigate materials with critical composition by combinatorial film technique.
Process development for novel low temperature plasma synthesized nanocarbon–based biosensors (2017)

International audience
The Cactus Worm: Experiments with Dynamic Resource Discovery and Allocation in a Grid Environment (2001)

The ability to harness heterogeneous, dynamically available grid resources is attractive to typically resource-starved computational scientists and engineers, as in principle it can increase, by significant factors, the number of cycles that can be delivered to applications. However, new adaptive application structures and dynamic runtime system mechanisms are required if we are to operate effectively in grid environments. To explore some of these issues in a practical setting, the authors are developing an experimental framework, called Cactus, that incorporates both adaptive application structures for dealing with changing resource characteristics and adaptive resource selection mechanisms that allow applications to change their resource allocations (e.g., via migration) when performance falls outside specified limits. The authors describe the adaptive resource selection mechanisms and describe how they are used to achieve automatic application migration to “better” resources following performance degradation. The results provide insights into the architectural structures required to support adaptive resource selection. In addition, the authors suggest that the Cactus Worm affords many opportunities for grid computing.
My Goal Is to Teach Music and They Ask Me about Global Education (2008)

It has been shown through research with primary and secondary Human Society and Its Environment (HSIE/SOSE) pre-service teachers (Horsley, Newell and Stubbs, 2005) that undergraduate disciplinary study provides new teachers with knowledge schemas they consider are related to their profession. Consequently, research demonstrated that when new teachers tried to construct Global Knowledge Disciplinary Schemas they called on their undergraduate studies in order to incorporate the term 'global education.' The question arises about what existing knowledge do pre-service music teachers call upon to construct their schemas of Global Education. This paper investigates ways these disciplinary schemas connect with knowledge, skills and values for pre-service teachers of high school music.
Advances in Polyurethane Coatings (1969 to Early 1972) (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAdvances in Polyurethane Coatings (1969 to Early 1972)Wen-Hsuan Chang, Rogers L. Scriven, John R. Peffer, and Samuel Porter Jr.Cite this: Ind. Eng. Chem. Prod. Res. Dev. 1973, 12, 4, 278–288Publication Date (Print):December 1, 1973Publication History Published online1 May 2002Published inissue 1 December 1973https://pubs.acs.org/doi/10.1021/i360048a004https://doi.org/10.1021/i360048a004research-articleACS PublicationsRequest reuse permissionsArticle Views712Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Prostate-Specific Membrane Antigen–Targeted Radiohalogenated PET and Therapeutic Agents for Prostate Cancer (2016)

Radiohalogenated agents are often the first line of pursuit in the development of new radiopharmaceuticals-whether antibodies, peptides, or small molecules-because of their ease of synthesis, lack of substantial steric perturbation of the original affinity agent (in some cases, providing enhanced affinity), and capacity to be transformed into therapeutics (in some cases, with a mere switch of an isotope). They often provide proof of a principle before optimization for pharmacokinetics or generation of radiometallated agents, when the latter are necessary. In particular, <sup>18</sup>F has been well integrated into normal clinical work flow in the form of <sup>18</sup>F-FDG for oncologic imaging, with reliable daily production and distribution to sites for immediate use, without the need for on-site preparation. Here we discuss radiohalogenated versions of imaging and therapeutic agents targeting the prostate-specific membrane antigen (PSMA); these were among the first such agents to be synthesized and used clinically. PSMA is highly expressed on prostate cancer epithelial cells and is currently being extensively investigated around the world as a target for imaging and therapy of prostate cancer. Additionally, the presence of PSMA on nonprostate tumor neovasculature has opened the possibility of PSMA-targeted molecules as generalizable cancer imaging and therapy agents. We focus on <sup>18</sup>F-labeled agents for PET, as they begin to redefine-along with the corresponding <sup>68</sup>Ga-labeled agents discussed elsewhere in this supplement to The Journal of Nuclear Medicine-the management of prostate cancer across a variety of clinical contexts.
Chemical Ecology—A Chapter of Modern Natural Products Chemistry (1976)

Abstract The chemical reaction of arthropods to their environment, i.e. their chemical ecology, can be studied particularly well with water beetles. Stenus comma , an aquatic beetle weighing only 2.5 mg, saves itself from drowning with the aid of an alkaloid, and the water beetle Ilybius fenestratus defends itself against small mammalian predators with a compound belonging to the same class. The water beetle Platambus maculatus employs a diterpene for precisely the same purpose and the whirligig beetle a norsesquiterpene, which also offers protection against troublesome microorganisms. As chemical artists, the ants can hardly be surpassed. In particular, the myrmecine ants guarantee their food supplies with plant growth substances. Since these compounds, depending upon concentration, can also act as inhibitors, we are confronted with an excellent example of an ecological equilibrium being established with the aid of organic chemicals. Even the little parasitic bombardier beetle Paussus favieri is tolerated, on account of its defensive chemistry, in the nest of the myrmecine ant Pheidole . In contrast, inorganic compounds are largely responsible for the stability of spiders' webs.
Abstract B38: p90RSK mediates resistance to PI3K-pathway inhibitors in breast cancer (2015)

Abstract The PI3K signaling pathway regulates diverse cellular processes including proliferation, survival and metabolism and is aberrantly activated in human cancer. As such, numerous compounds targeting the PI3K pathway are currently being clinically evaluated for the treatment of cancer and several have shown some early indications of efficacy in breast cancer. However, resistance against these agents, both de novo and acquired, may ultimately limit the efficacy of these compounds. Here, we have taken a systematic functional approach to uncover potential mechanisms of resistance to PI3K inhibitors and have identified several genes whose expression promotes survival under conditions of PI3K/mTOR blockade, including the ribosomal S6 kinases RPS6KA2 (RSK3) and RPS6KA6 (RSK4). We demonstrate that overexpression of RSK3 or RSK4 supports proliferation upon PI3K inhibition both in vitro and in vivo, in part through the attenuation of apoptotic response and upregulation of protein translation. Notably, the addition of MEK- or RSK-specific inhibitors can overcome these resistance phenotypes, both in breast cancer cell lines and patient derived xenograft models with elevated levels of RSK activity. These observations provide a strong rationale for the combined use of RSK and PI3K pathway inhibitors to elicit favorable responses in breast cancer patients with activated RSK. Citation Format: Pieter J.A. Eichhorn, Violeta Serra, Celina Garcia-Garcia, Yasir H. Ibrahim, Lumilla Prudkin, Josep-Lluis Parra, Aleix Prat, William C. Hahn, So Young Kim, Jose Baselga. p90RSK mediates resistance to PI3K-pathway inhibitors in breast cancer. [abstract]. In: Proceedings of the AACR Special Conference: Targeting the PI3K-mTOR Network in Cancer; Sep 14-17, 2014; Philadelphia, PA. Philadelphia (PA): AACR; Mol Cancer Ther 2015;14(7 Suppl):Abstract nr B38.
Nuclear Magnetic Resonance Studies of Bicyclic Thiophene Derivatives. I. Ring Current Effects of the Benzene Ring on the Hα and Hβ Signals of the Thiophene Ring in Benzoylthiophene, Thienopyrimidine and Thienodiazepine Derivatives (1975)

Abstract Various thiophene derivatives such as 4-phenyIthienopyrimidines (1), 2-acetylamino-3-benzoylthiophenes (2), 5-phenyl-1,4-thienodiazepines (3) and 5-phenyl-1,4-thienodiazepine-4-oxides (4) have been prepared. Their proton magnetic resonance spectra show that Hα and Hβ of the thiophene ring become more shielded with an increase in bulk of ortho substituent of the benzene ring. This is attributed to the shielding effect of the benzene ring; a steric repulsion between ortho substituent of the benzene ring and some atoms on another moiety of each molecule. Such a repulsion should bring the benzene ring out of the plane of the thiophene ring. The degree of shielding on Hβ by the benzene ring is found to increase in the order 1&amp;lt;2&amp;lt;3&amp;lt;4. This can be taken to indicate that the amount of steric repulsion depends not only on the bulk of ortho substituent of the benzene ring but also on the geometry of each ring system of 1–4.
Photoreflectance characterization of surface Fermi level in as-grown GaAs(100) (1990)

Photoreflectance (PR) spectroscopy has been used to study the surface Fermi level in GaAs by taking account of photovoltaic properties at the semiconductor surface. The PR signal amplitude ‖ΔR/R‖ is proportional to a modulating photovoltage Vm generated by a modulation light irradiation. To modify the surface potential, the sample was irradiated by a third perturbing light, i.e., a continuous bias light Pb, together with the modulation light. The modulation light power dependence of ‖ΔR/R‖ is extremely sensitive to bias light intensity, surface Fermi level, and temperature. From the analysis of the temperature dependence of ‖ΔR/R‖ on modulation-light power, the surface Fermi level of 0.47±0.09 eV below the conduction band was determined for a molecular beam epitaxially-grown GaAs(100).
How Color Enhances Visual Memory for Natural Scenes (2005)

We offer a framework for understanding how color operates to improve visual memory for images of the natural environment, and we present an extensive data set that quantifies the contribution of color in the encoding and recognition phases. Using a continuous recognition task with colored and monochrome gray-scale images of natural scenes at short exposure durations, we found that color enhances recognition memory by conferring an advantage during encoding and by strengthening the encoding-specificity effect. Furthermore, because the pattern of performance was similar at all exposure durations, and because form and color are processed in different areas of cortex, the results imply that color must be bound as an integral part of the representation at the earliest stages of processing.
Standardization in Isoelectric Focusing on Ultrathin-Layer Rehydratable Polyacrylamide Gels (1987)

Rehydratable, stabilized, dry polyacrylamide gels (250-275μ thick) were compared to those made conventionally, both fresh and stored in sealed aluminized bags, for their characteristics in isoelectric focusing. Removal of the impurities and unknown polymerization products by washing, following the polymerization procedure, produced a gel, that on rehydration with ampholytes in the presence of glycerol had a conductance five-fold or more lower than that of a conventionally prepared gels of the same volume and ampholyte concentration, as marked by a lower milliamperage at the same voltage gradient. The lower conductance allowed higher voltage gradients to be applied at completely controllable Joule heat loads, which increases the resolution of the system. Comparative studies of the separation of hemoglobins on Pharmalyte™ narrow range pH gradients indicated that with conventionally cast gels, either fresh or stored, there were additional peroxidase positive hemoglobin-like bands present in both fresh standards and in patient whole blood samples soaked into PKU filter paper test strips. These bands were presumably due to artifactual binding products of the polymerization process with ampholyte and or the hemoglobins. The rehydratable gels were found to be stable on storage, giving reproducible patterns after over one year of storage at room temperature.
Comprehensive sequence analysis of horseshoe crab cuticular proteins and their involvement in transglutaminase‐dependent cross‐linking (2005)

Arthropod cuticles play an important role as the first barrier against invading pathogens. We extensively determined the sequences of horseshoe crab cuticular proteins. Proteins extracted from a part of the ventral side of the cuticle were purified by chitin-affinity chromatography, and separated by two-dimensional SDS/PAGE. Proteins appearing on the gel were designated high molecular mass chitin-binding proteins, and these proteins were then grouped into classes based on their approximate isoelectric points and predominant amino acid compositions. Members of groups designated basic G, basic Y, and acidic S groups contained a so-called Rebers and Riddiford consensus found in arthropod cuticular proteins. Proteins designated acidic DE25 and DE29 each contained a Cys-rich domain with sequences similar to those of insect peritrophic matrix proteins and chitinases. In contrast, basic QH4 and QH10 contained no consensus sequences found in known chitin-binding proteins. Alternatively, a low molecular mass chitin-binding fraction was prepared by size exclusion chromatography, and 15 low molecular mass chitin-binding proteins, named P1 through P15, were isolated. With the exception of P9 and P15, all were found to be identical to known antimicrobial peptides. P9 consisted of a Kunitz-type chymotrypsin inhibitor sequence, and P15 contained a Cys-rich motif found in insulin-like growth factor-binding proteins. Interestingly, we observed transglutaminase-dependent polymerization of nearly all high molecular mass chitin-binding proteins, a finding suggests that transglutaminase-dependent cross-linking plays an important role in host defense in the arthropod cuticle, analogous to that observed in the epidermal cornified cell envelope in mammals.
From Wafers to Modules to Mass Production: Solving All Bottlenecks in Silicon Heterojunction Technology (2018)

Silicon heterojunction solar cells have less manufacturing steps and have allowed achieving higher efficiency than PERC cells.<br> However the market has been slow in taking up the technology. Here we show some of the obstacles that have been overcome in the last 10 years which make the technology more ready than ever for a mass market launch.
Serotonin 5-HT2B receptor loss of function mutation in a patient with fenfluramine-associated primary pulmonary hypertension (2003)

Loss of serotonin 5-HT(2B) receptor function may predispose to fenfluramine-associated PPH in man.
The Effects of Compression-Garment Pressure on Recovery After Strenuous Exercise (2017)

The pressures exerted by a compression garment affect recovery after exercise-induced muscle damage, with higher pressure improving recovery of muscle function.
Pre-equalization in combination with transmit diversity for OFDMA code-division multiplexing systems in fading channels (2005)

The potential of combining channel pre-equalization with transmit diversity for orthogonal frequency-division multiple-access code-division multiplexing (OFDMA-CDM) systems is investigated. The pre-equalization exploits the channel knowledge which is presumed to be available at the transmitter (Tx). The transmission signal is pre-distorted according to the channel state information (CSI) which can be made available, for example, by using time division duplex (TDD) mode. In TDD mode and under the assumption that CSI changes slowly in time, CSI estimated from a received slot can be used for pre-equalization of the next transmission slot. Concerning transmit diversity, we consider space-frequency block coding (SFBC) and transmit selection diversity (TSD). It turns out that TSD significantly outperforms SFBC. Moreover, systems with pre-equalization and TSD exhibit lower complexity than systems with pre-equalization and SFBC, since in the former case CSI is needed only at Tx, while in the latter case CSI is required at both Tx and receiver (Rx). In addition, it is shown that TSD is the optimal transmit diversity technique in the sense of bit error rate (BER) minimization in the case when CSI is available at Tx.
Abstract 3391: Alteration of mammary tumor cell behavior by FLIZ1 (2014)

Abstract Fetal liver zinc finger protein (FLIZ1, ZC3H8) was previously described as a negative regulator of GATA3 expression in T cells. GATA3 also is an important determinant of mammary cell fate and breast tumor cell behavior. We hypothesized that FLIZ1 also regulates GATA3 in the mammary gland, thereby influencing normal and tumor cell processes controlled by GATA3. We identified tumor cell lines with high levels of FLIZ1 expression, and transfected them with vectors driving expression of FLIZ1-interfering RNAs. Stable transfectants (Flizout cells) were evaluated for ability to migrate in a wound healing assay, and were found to have decreased mobility. Flizout cells also grew more slowly and with more pronounced epithelial morphology in media containing charcoal-stripped serum, suggesting increased dependence on steroid hormones. Flizout cells were compared to control cells in proliferation assays, and were found to grow at equivalent rates in standard media, but Flizout cells grew at decreased rates in the presence of tamoxifen. We implanted Flizout cells and controls into the mammary glands of syngeneic female mice, which were then treated with tamoxifen or peanut oil vehicle alone. Flizout cells grew more slowly in tamoxifen-treated animals, and tissue weights were significantly less than controls. In order to determine if FLIZ1 plays a role in the normal mammary gland, we assessed its expression during stages of mouse mammary gland development by immunoblot, and found FLIZ1 expression increased during mammary involution. These data are consistent with a role for FLIZ1 in regulation of mammary cell growth and tumor cell behavior. Citation Format: Torri Anderson, Christopher Cali, Katherine Bell, Keith G. Danielson, Ashley Klein, Christina Martin, Sara Radecki, Adam Santoro, John A. Schmidt, Janice E. Knepper. Alteration of mammary tumor cell behavior by FLIZ1. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 3391. doi:10.1158/1538-7445.AM2014-3391
Nature of intermediates in the catalytic decomposition of hydrogen peroxide by ferric ions (1962)

M. L. Kremer, Trans. Faraday Soc., 1962, 58, 702 DOI: 10.1039/TF9625800702
Figure S1 from Targeting fatty acid reprogramming suppresses CARM1-expressing ovarian cancer (2023)

&lt;p&gt;CARM1 regulates genes involved in fatty acid synthesis pathway.&lt;/p&gt;
Enzymatic Digestion of Proteins on PVDF Membranes (1995)

Enzymatic digestion of membrane-bound proteins is one of the most widely used procedures for determining the internal amino acid sequence of proteins that either have a blocked amino terminus or require two or more stretches of sequence data for DNA cloning or confirmation of protein identification. Because the final step of protein purification is usually SDS-PAGE, electroblotting to either polyvinylidene difluoride (PVDF) or nitrocellulose is the simplest and most common procedure for recovering protein free of contaminants (e.g., SDS or acrylamide) with a high yield. As described in this unit, PVDF is preferred over nitrocellulose because it can be used for a variety of other structural analysis procedures, such as amino-terminal sequence analysis and amino acid analysis. In addition, peptide recovery from PVDF membranes is higher than from nitrocellulose, particularly from higher-retention PVDF (e.g., ProBlott, Transblot, Westran, or Immobilon P(sp)). Finally, PVDF-bound protein can be stored dry, as opposed to nitrocellulose-bound protein, which must remain wet during handling and storage to prevent loss of peptides during digestion.
Runx1 Is Expressed in Adult Mouse Hematopoietic Stem Cells and Differentiating Myeloid and Lymphoid Cells, But Not in Maturing Erythroid Cells (2004)

The transcription factor Runx1 marks all functional hematopoietic stem cells (HSCs) in the embryo and is required for their generation. Mutations in Runx1 are found in approximately 25% of acute leukemias and in familial platelet disorder, suggesting a role for Runx1 in adult hematopoiesis as well. A comprehensive analysis of Runx1 expression in adult hematopoiesis is lacking. Here we show that Runx1 is expressed in functional HSCs in the adult mouse, as well as in cells with spleen colony-forming unit (CFU) and culture CFU capacities. Additionally, we document Runx1 expression in all hematopoietic lineages at the single cell level. Runx1 is expressed in the majority of myeloid cells and in a smaller proportion of lymphoid cells. Runx1 expression substantially decreases during erythroid differentiation. We also document effects of reduced Runx1 levels on adult hematopoiesis.