gebhart/patrepeval huggingface dataset:
Effect of lethal doses of bacterial endotoxin (E. coli) on sympathetic neurohormones in the rabbit (1960)

Lethal doses of E. coli endotoxin, administered intravenously, produced an immediate, precipitous fall in blood pressure, which returned to near normal levels over the next hour. Approximately 1 hour after endotoxin administration the blood pressure began to fall gradually and continued to fall until the death of the animal. During the period of immediate blood pressure fall there was no significant increase in the circulating catecholamines and no decrease in the adrenal content of these hormones. This suggests that the sympathetic nervous system may be depressed during the initial phases of endotoxin poisoning so that the sympathetic discharge which is seen during hypotension, produced by other means, is inoperative. When the pressure returned to near normal levels, the circulating catecholamine concentrations were elevated and the adrenal gland content of these materials was decreased. When the pressure dropped to levels below 60 mm Hg, 4–6 hours after endotoxin administration, the circulating catecholamine level was still statistically elevated and the adrenal content of catecholamines was further depressed. These experiments demonstrate that the blood pressure levels, during endotoxin administration, do not parallel expected peripheral catecholamine concentrations. During the late stages of endotoxin poisoning there is evidence that the animal becomes refractive to increased endogenous epinephrine and norepinephrine.
Dynamic deformation measurement of dual-wavelength arbitrary phase-shifting digital holography with automatic phase-shift detection (2021)

Dual-wavelength arbitrary phase-shifting digital holography with automatic phase-shift detection is first proposed in this study. Holograms with two wavelengths and the interference fringes used to detect the phase-shifting amount for each wavelength were simultaneously recorded in one image using the space-division multiplexing technique. Compared with conventional methods, the proposed approach can achieve simultaneous phase shifting of the reference beams of two wavelengths, which substantially reduces recording time and does not require excessive phase-shifting device precision. The proposed and conventional methods were quantitatively evaluated with numerical simulations, and a dynamic deformation measurement was obtained using the system. In the quantitative evaluation of the simulation, the root-mean-square errors of amplitude and phase images reconstructed by the proposed method were reduced by 12% and 19% compared to the conventional method, respectively. Both numerical simulations and experiments verified the effectiveness of the proposed method.
Supplementary Table 1 from Comprehensive Molecular Characterization of Salivary Duct Carcinoma Reveals Actionable Targets and Similarity to Apocrine Breast Cancer (2023)

&lt;p&gt;Table S1. List of genes and additional intronic regions included in the MSK-IMPACT next-generation sequencing panel.&lt;/p&gt;
Low latency packet processing in software routers (2014)

Commodity hardware can be used to build a software router that is capable of high-speed packet processing while being programmable and extensible. Therefore, software routers provide a cost-efficient alternative to expensive, special hardware routers. The efficiency of packet processing in resource-constrained nodes (e.g. software routers) can be strongly increased through parallel processing with commodity hardware based on multi-core processors. However, intra-node resource contention can have a strong negative impact on the corresponding network node. We describe how multi-core software routers can be optimized for low latency support by utilizing the technologies available in commodity PC hardware. For the analysis we used our approach for modeling of resource contention in resource-constrained nodes which is also implemented as the resource-management extension module for ns-3. Based on that, we derived a specific software router model which we used to optimize the performance. Our measurements show that the configuration of a software router has significant influence on the performance. The results can be used for parameter tuning in such systems.
An Efficient Algorithm for Computing Optimal (s, S) Policies (1984)

This paper presents an algorithm to compute an optimal (s, S) policy under standard assumptions (stationary data, well-behaved one-period costs, discrete demand, full backlogging, and the average-cost criterion). The method is iterative, starting with an arbitrary, given (s, S) policy and converging to an optimal policy in a finite number of iterations. Any of the available approximations can thus be used as an initial solution. Each iteration requires only modest computations. Also, a lower bound on the true optimal cost can be computed and used in a termination test. Empirical testing suggests very fast convergence.
Konstruktionselemente der Feinmechanik (2018)

You have accessKonstruktionselemente der FeinmechanikSep 2018Konstruktionselemente der FeinmechanikWerner KrauseWerner Krausehttps://doi.org/10.3139/9783446449923.fmSectionsAboutPDF ToolsAdd to FavoritesDownload CitationTrack CitationsCopy LTI LinkPDF key 'share (en)' returned an object instead of string.FacebookTwitterEmailLinkedIn next chapter FiguresReferencesRelatedDetails 2018Pages: I-XXPrint ISBN: 978-3-446-44796-7eISBN: 978-3-446-44992-3 Copyright & Permissions© 2018 Carl Hanser Verlag GmbH & Co. KGPDF downloadLoading ...
Management of patients with interstitial cystitis or chronic pelvic pain of bladder origin: a consensus report (2005)

This paper presents recommendations from a multidisciplinary panel for the evaluation, diagnosis, treatment, and follow-up care of patients with IC or CPP of bladder origin.
Origine de l'aiguille creuse : Julien Wyplosz, « Qui a inventé l'aiguille creuse ? », La Revue du praticien, 2003 (2003)

Labrude Pierre. Origine de l'aiguille creuse : Julien Wyplosz, « Qui a invente l'aiguille creuse ? », La Revue du praticien, 2003. In: Revue d'histoire de la pharmacie, 91ᵉ annee, n°340, 2003. pp. 675-676.
An immunology course focused on faculty research interest provides key inputs for research productivity at a primarily undergraduate institution (P4529) (2013)

Abstract Rapid turnover of trained undergraduate student researchers and limited time faculty and students can devote to research activities during the academic year are some of the roadblocks to maintaining a productive research program at a primarily undergraduate institution. At Macalester College, a highly selective liberal arts institution, we have addressed these issues, in part, through the design and implementation of a "Research in Immunology" course that is open by application to a group of eight second- or third-year students each spring. The course consists of a journal club with reading, writing and presentation activities that immerse students in the primary literature around the faculty member’s research question, and a laboratory component that emphasizes intensive skill building while fully exposing students to novel, unanswered questions. A subset of these students then enter the lab the following summer with a high level of intellectual and technical preparation and many are highly productive in the laboratory for 2+ years providing continuity of trained personnel, critical peer mentoring and a degree of involvement in and ownership of the research problems that is rare among undergraduates. In the past 6 years, I have trained 40 students in my laboratory most of whom have taken this course. Of these, 30% have completed honors research projects and earned co-authorship on manuscripts, and 6 have gone on to PhD programs in immunology/biomedicine.
Low levels of serum ferritin and moderate transferrin saturation lead to adequate hemoglobin levels in hemodialysis patients, retrospective observational study (2017)

In this study, the iron status of serum ferritin <90 ng/mL and transferrin saturation ≥20% was optimal in hemodialysis patients receiving recombinant human erythropoietin for anemia therapy. This result indicates that the threshold values for the optimal iron status may be lower than those currently recommended in iron-level management guideline.
Superresolving dendritic spine morphology with STED microscopy under holographic photostimulation (2016)

Emerging all-optical methods provide unique possibilities for noninvasive studies of physiological processes at the cellular and subcellular scale. On the one hand, superresolution microscopy enables observation of living samples with nanometer resolution. On the other hand, light can be used to stimulate cells due to the advent of optogenetics and photolyzable neurotransmitters. To exploit the full potential of optical stimulation, light must be delivered to specific cells or even parts of cells such as dendritic spines. This can be achieved with computer generated holography (CGH), which shapes light to arbitrary patterns by phase-only modulation. We demonstrate here in detail how CGH can be incorporated into a stimulated emission depletion (STED) microscope for photostimulation of neurons and monitoring of nanoscale morphological changes. We implement an original optical system to allow simultaneous holographic photostimulation and superresolution STED imaging. We present how synapses can be clearly visualized in live cells using membrane stains either with lipophilic organic dyes or with fluorescent proteins. We demonstrate the capabilities of this microscope to precisely monitor morphological changes of dendritic spines after stimulation. These all-optical methods for cell stimulation and monitoring are expected to spread to various fields of biological research in neuroscience and beyond.
Reactions of Unsaturated Fatty Alcohols. IV. Oxidative Degradation of Lauryl Isopropyl Ether1 (1959)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReactions of Unsaturated Fatty Alcohols. IV. Oxidative Degradation of Lauryl Isopropyl Ether1L. E. GAST, C. B. COLEMAN, and H. M. TEETERCite this: J. Org. Chem. 1959, 24, 2, 160–165Publication Date (Print):February 1, 1959Publication History Published online1 May 2002Published inissue 1 February 1959https://pubs.acs.org/doi/10.1021/jo01084a004https://doi.org/10.1021/jo01084a004research-articleACS PublicationsRequest reuse permissionsArticle Views156Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
CaPaR: A Career Path Recommendation Framework (2017)

In today's world, recommendation systems are used to solve the problem of information overload in many areas allowing users to focus on important information based on their interests. One of the areas where such systems can play a major role is in helping students achieve their career goals by generating personalized job and skill recommendations. At present, there are many job posting websites providing a huge amount of information and students need to spend hours to find jobs that match their interests. At the same time, existing job recommendation systems only consider the user's field of interest, but do not take into consideration the user's profile and skills, which can generate more relevant career recommendations for users. In this work, we propose CaPaR, a Career Path Recommendation framework, which addresses such shortcomings. Using text mining and collaborative filtering techniques the system first scans the user's profile and resume, identifies the key skills of the candidate and generates personalized job recommendations. Moreover, the system recommends additional skills to students required for related job openings, as well as learning resources for each skill. In this way, the system not only allows its users to explore large amounts of information, but also expand their portfolio and resume to be able to advance their careers further. We experiment and evaluate the various recommendation algorithms with real-world data collected from the San Jose State University career center web site.
Monoclonal Antibodies against Components of the Classical Pathway of Complement (1989)

Activation of the classical pathway of complement involves several binding and enzymatic cleavage processes. Binding and enzymatic activation results in the appearance of new structures in the individual components. This report describes the different activation steps for C1q, C1r, C1s, C4 and C2 and summarizes monoclonal antibodies reported so far which recognize either conserved epitopes or activation-dependent epitopes with particular emphasis on neoepitopes occurring during the activation cascade.
Dynamic Effects of Impact Machine Foundations (2008)

Foundations for machines with impact loads are widespread powerful sources of industrial vibrations. These foundations mostly transmit vertical dynamic loads on the ground and generate ground vibrations which may harmfully affect surrounding buildings. Dynamic effects range from serious disturbances of working conditions for sensitive devices and people to visible structural damage. Natural frequency of vertical machine foundation vibrations and complete vibration records of ground and structure vibrations can be predicted prior to installation of machine foundations. Diverse measures can be used to mitigate dynamic effects of impact machine foundations.
ChemInform Abstract: Convolutamines A‐E, Novel β‐Phenylethylamine Alkaloids from Marine Bryozoan Amathia convoluta. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Mode-locking ultrafast solid-state lasers with saturable Bragg reflectors (1996)

We discuss mode-locking of low-gain solid-state lasers using a semiconductor saturable Bragg reflector structure. This recently developed low-loss mode-locking device consists of a single quantum well which acts as a saturable absorber incorporated into a high-reflectivity Bragg mirror. Highly stable mode-locking in solid-state lasers results from an ultrafast transient reflectivity in the device that is caused by saturation of the excitonic absorption in near-resonant conditions.
Multiband OFDM for Covert Acoustic Communications (2008)

A multiband OFDM transmitter and receiver are presented for underwater communications at low SNR. Compared with a single-band OFDM scheme, the multiband approach leads to a considerable reduction in the receiver complexity. The proposed system has been tested at sea with 16 subbands covering a total bandwidth of 3.6 kHz, at user data rates of 4.2 and 78 bit/s, and over ranges up to 52 km. At the lower rate, successful message recovery is achieved on a single hydrophone at SNRs down to -17 dB in a benign channel. In channels with a severe delay-Doppler spread the critical SNR rises by some 4 dB. At 78 bit/s the limits of the OFDM signaling scheme are clearly revealed, but at 4.2 bit/s the performance is limited by failure of signal detection and initial synchronization.
Radiomics-based assessment of ultra-widefield leakage patterns and vessel network architecture in the PERMEATE study: insights into treatment durability (2020)

Two computer-extracted UWFA radiomics-based descriptors were identified as potential biomarkers for predicting treatment durability and tolerance of longer treatment intervals. Conventional treatment parameters were not significantly different between these same groups.
Nonlinear Optics Of Nematic Liquid Crystals (1987)

The fundamental mechanisms for optical nonlinearities, and recent experimental studies of nonlinear optical processes such as optical wave mixings, beam amplifications, bistability and self-phase modulation effects are reviewed.
Special Metallurgical Welding Considerations for Nickel and Cobalt Alloys and Superalloys (1993)

Abstract The process of making assemblies of solid-solution and precipitation hardening groups of alloys and superalloys often requires welding of dissimilar metals, welding of diffusion-bonded materials, and sometimes weld overlay cladding and even thermal spraying that in turn requires special knowledge and treatments developed specifically for each material. This article emphasizes the special metallurgical welding considerations for welding solid-solution and precipitation hardening nickel alloys, cobalt alloys, and superalloys.
Syntheses and Crystal Structures of 4,5‐Dihydro‐2‐(2′‐hydroxyphenyl)oxazole‐Containing Metal Complexes (1991)

Abstract The synthesis of the complexes 3 of various metals ligated to chiral 4,5‐dihydro‐2‐(2′‐oxidophenyl‐ϰ O )oxazoles‐ϰ N is described ( Scheme ). Three of them, i.e. 3a , 3e , and 3f containing Cu II , Zn II and Ni II , respectively, were analyzed by X‐ray diffraction studies. A series of Cu II complexes ( 6a – d ) with differently substituted dihydrooxazoles have been synthesized.
Editorial: Leptin Resistance in Metabolic Disorders: Possible Mechanisms and Treatments (2017)

EDITORIAL article Front. Endocrinol., 02 November 2017Sec. Cellular Endocrinology Volume 8 - 2017 | https://doi.org/10.3389/fendo.2017.00300
Mapping of Cortical Activity in the First Two Decades of Life: A High-Density Sleep Electroencephalogram Study (2010)

Evidence that electroencephalography (EEG) slow-wave activity (SWA) (EEG spectral power in the 1-4.5 Hz band) during non-rapid eye movement sleep (NREM) reflects plastic changes is increasing (Tononi and Cirelli, 2006). Regional assessment of gray matter development from neuroimaging studies reveals a posteroanterior trajectory of cortical maturation in the first three decades of life (Shaw et al., 2008). Our aim was to test whether this regional cortical maturation is reflected in regional changes of sleep SWA. We evaluated all-night high-density EEG (128 channels) in 55 healthy human subjects (2.4-19.4 years) and assessed age-related changes in NREM sleep topography. As in adults, we observed frequency-specific topographical distributions of sleep EEG power in all subjects. However, from early childhood to late adolescence, the location on the scalp showing maximal SWA underwent a shift from posterior to anterior regions. This shift along the posteroanterior axis was only present in the SWA frequency range and remained stable across the night. Changes in the topography of SWA during sleep parallel neuroimaging study findings indicating cortical maturation starts early in posterior areas and spreads rostrally over the frontal cortex. Thus, SWA might reflect the underlying processes of cortical maturation. In the future, sleep SWA assessments may be used as a clinical tool to detect aberrations in cortical maturation.
Novel and effective strategy of dual bis(trifluoromethylsulfonyl)imide imidazolium ionic liquid immobilized on periodic mesoporous organosilica for greener cycloaddition of carbon dioxide to epoxides (2019)

Novel periodic mesoporous organosilica supported ionic liquids were prepared, characterized and evaluated as catalysts for cycloaddition of CO<sub>2</sub> to epoxides.
Steady-State, Applied-Field, Rectangular Magnetoplasmadynamics Thruster Using Hollow Cathode (2012)

This paper reports operation characteristics of a steady-state, applied-field magnetoplasmadynamics (MPD) thruster using a hollow cathode. In order to improve cathode performance, a tungsten rod was replaced with a hollow cathode which had better electron emission performance and a longer lifetime. A rectangular acceleration section was employed between electrodes. The discharge voltage and thrust were measured with varying the applied magnetic field, discharge current, propellant mass flow rate and acceleration channel width and height.
Fat navigators and Moiré phase tracking comparison for motion estimation and retrospective correction (2019)

This work confirms both FatNavs and MPT as excellent retrospective motion correction methods for very high resolution imaging of cooperative subjects.
Ligand-Enabled Reactivity and Selectivity in a Synthetically Versatile Aryl C–H Olefination (2009)

The Mizoroki-Heck reaction, which couples aryl halides with olefins, has been widely used to stitch together the carbogenic cores of numerous complex organic molecules. Given that the position-selective introduction of a halide onto an arene is not always straightforward, direct olefination of aryl carbon-hydrogen (C-H) bonds would obviate the inefficiencies associated with generating halide precursors or their equivalents. However, methods for carrying out such a reaction have suffered from narrow substrate scope and low positional selectivity. We report an operationally simple, atom-economical, carboxylate-directed Pd(II)-catalyzed C-H olefination reaction with phenylacetic acid and 3-phenylpropionic acid substrates, using oxygen at atmospheric pressure as the oxidant. The positional selectivity can be tuned by introducing amino acid derivatives as ligands. We demonstrate the versatility of the method through direct elaboration of commercial drug scaffolds and efficient syntheses of 2-tetralone and naphthoic acid natural product cores.
Error performance study of MPPM optical communication systems with finite extinction ratios (2016)

Multi-pulse pulse position modulation (MPPM) aims to improve the receiver bandwidth efficiency with respect to M-ary PPM. It is regarded as an attractive modulation scheme that can be utilized in both optical fibers and free-space optical (FSO) communication systems. In this paper, the error performance of MPPM optical communication systems over an ideal channel is studied, with consideration of the impact of the transmitter extinction ratio (ER) on the symbol error rate (SER). The study considers SER for symbol sizes M ϵ {16,32,64}. The values of the number of ON slots per symbol considered are N ϵ {1, 2, 3, 4}, and the ER values are r ϵ {10, 20, 30} dB. Monte-Carlo simulation shows that finite ER degrades the performance of MPPM systems. It also shows that MPPM systems, despite their improved bandwidth efficiency, have worse error performance than the M-ary PPM systems.