gebhart/patrepeval huggingface dataset:
Identification of novel meristem factors involved in shoot regeneration through the analysis of temperature‐sensitive mutants of Arabidopsis (2008)

Adventitious organogenesis in plant tissue culture involves de novo formation of apical meristems and should therefore provide important information about the fundamentals of meristem gene networks. We identified novel factors required for neoformation of the shoot apical meristem (SAM) through an analysis of shoot regeneration in root initiation defective3 (rid3) and root growth defective3 (rgd3) temperature-sensitive mutants of Arabidopsis. After induction of callus to regenerate shoots, cell division soon ceased and was then reactivated locally in the surface region, resulting in formation of mounds of dense cells in which adventitious-bud SAMs were eventually constructed. The rgd3 mutation inhibited reactivation of cell division and suppressed expression of CUP-SHAPED COTYLEDON1 (CUC1), CUC2 and SHOOT MERISTEMLESS (STM). In contrast, the rid3 mutation caused excess ill-controlled cell division on the callus surface. This was intimately related to enhanced and broadened expression of CUC1. Positional cloning revealed that the RGD3 and RID3 genes encode BTAF1 (a kind of TATA-binding protein-associated factor) and an uncharacterized WD-40 repeat protein, respectively. In the early stages of shoot regeneration, RGD3 was expressed (as was CUC1) in the developing cell mounds, whereas RID3 was expressed outside the cell mounds. When RID3 was over-expressed artificially, the expression levels of CUC1 and STM were significantly reduced. Taken together, these findings show that both negative regulation by RID3 and positive regulation by RGD3 of the CUC-STM pathway participate in proper control of cell division as a prerequisite for SAM neoformation.
Systematic Variation of Bidentate Ligands Used in Aryl Halide Amination. Unexpected Effects of Steric, Electronic, and Geometric Perturbations (1998)

This paper presents effects of varying bidentate phosphine steric properties, electronic properties, and bite angle on product ratios in the amination of aryl bromides. Comparisons of the ratios of amine products to dehydrohalogenation products showed that catalysts containing electron rich, modestly hindered phosphines with small bite angles (∼90°) gave the best selectivities. Surprisingly, the arene side product formed from reaction of alkylamines deuterated in the N−H position or deuterated in the position α to the nitrogen showed low levels of deuterium incorporation in many examples. Steric properties and ligand bite angle had the greatest impact on the selectivity for monoarylation versus diarylation of primary amines; ligands with small bite angles gave higher monoarylation-to-diarylation ratios, as did ligands with increased steric bulk. Electron poor or sterically hindered bidentate phosphines reduced the amount of product resulting from aryl exchange of electron rich palladium-bound arenes with those of aryl groups on the phosphine ligands.
Analysis of a nano-porous multi-layer film for thermal radiation barrier coatings (2011)

A highly reflective thermal radiation barrier coating (TRBC) made of a multi-layer film is studied for high temperature applications. The multi-layer film with a periodic microstructure consisting of cylindrical nano-pores acts a photonic band gap (PBG) crystal. The coating is constructed such that pores are arranged periodically along the in-plane directions and axes of the pores are parallel to the thickness direction. The pore diameter is varied periodically through the thickness to form a multi-layer film of alternating low and high porosities. The primary motivation behind considering this microstructure is that it can be fabricated from aluminum dioxide, which remains stable at high temperatures. The reflectivity of a single layer with uniform porosity is computed by numerically solving Maxwell’s equations, by considering both the microstructure explicitly and a homogenized layer to gain insights into the effect of pore size on the reflectivity of the nano-porous layer. Based on the study of the single layer, two microstructures with different arrangements of pores are designed to exploit the effect of microstructure to widen the band gap of the PBG crystal and to increase the reflectivity of the TRBC. Results of numerical simulations reveal that a wider band gap and higher reflectivity can be achieved by making the inter-pore distance of alternate layers of the multi-layer film comparable to the wavelength of the incident thermal radiation. A TRBC, which is made of a microstructure with a wider band gap and has increased reflectivity, will reflect a greater amount of incident heat energy over a wider range of frequencies.
Dicyclopentylboryl Trifluoromethanesulfonate (2001)

[72251-50-4] C11H18BF3O3S (MW 298.13) InChI = 1S/C11H18BF3O3S/c13-11(14,15)19(16,17)18-12(9-5-1-2-6-9)10-7-3-4-8-10/h9-10H,1-8H2 InChIKey = NSZIXDAISDDUFN-UHFFFAOYSA-N (Lewis acid for the preparation of vinyloxyboranes1-4) Alternate Name: dicyclopentylboryl triflate. Physical Data: colorless liquid, bp 70–72 °C/1.0 mmHg. Solubility: sol common inert organic solvents such as Et2O, CH2Cl2, and hexane. Form Supplied in: 0.5 M solution in CH2Cl2. Preparative Method: Trifluoromethanesulfonic Acid is added dropwise to an equimolar amount of tricyclopentylborane, with intermittent cooling to maintain the reaction temperature at approximately rt. Upon completion of the addition the reaction is stirred at rt for an additional 30 min followed by isolation of the product by vacuum distillation.2b Handling, Storage, and Precautions: the neat liquid as well as solutions are moisture and air sensitive. Therefore the material should be stored and transferred under a dry inert atmosphere.
CARDIOLOGY PATIENT PAGE (2002)

Summary Fainting is common in humans because the brain resides farabove the source of its blood supply (the heart). Any abruptdrop in blood pressure can lead to a faint. Fortunately, thecause is often innocent, and recurrence is infrequent. How-ever, a faint may warn of serious underlying heart disease. Inmany patients, the physician can distinguish between inno-cent and serious situations by taking a detailed medicalhistory, carefully reviewing the circumstances of the faint(s),examining the fainter, and perhaps obtaining a heart tracing(ECG) and/or a painless heart imaging test (echocardiogram).On occasion, additional medical tests are needed. Overall, in80% to 90% of fainters, a likely cause can be established andeffective treatment initiated. References 1. Brignole M, Alboni P, Benditt D, et al. Guidelines on management(diagnosis and treatment) of syncope. Eur Heart J. 2001;22:1256–1306.2. Benditt DG, Fahy GJ, Lurie GF, et al. Pharmacotherapy of neurallymediated syncope. Circulation. 1999;100:1242–1248.
Biosynthesis of acurin A and B in Aspergillus aculeatus (2017)

Aspergillus aculeatus is known for the commercial utilization in production of several enzymes. We have identified two stereoisomeric compounds of mixed polyketide-nonribosomal peptide origin in the extracts of A. aculeatus that we named acurin A and acurin B. The structures of the compounds strongly resemble the structure of the mycotoxin fusarin C produced by several Fusarium species. CRISPR-Cas9 was used to construct a non-homologous end-joining deficient strain of A. aculeatus, which enabled efficient gene deletions in the acurin gene cluster. Using RT-qPCR in combination with metabolite profiling of gene deletion strains, the acurin producing gene cluster was delineated, which allowed us to propose a biosynthetic pathway for formation of acurin. Our results show that acurin, in contrast to fusarin C, is biosynthesized by an individual polyketide synthase and non-ribosomal synthetase. At least six other enzymatic activities are required for the biosynthesis of acurin. This study shows how we exploit the CRISPR-Cas9 system for the rapid construction of fungal host strains that can be readily engineered to generate valuable knowledge.
Monitoring free flaps using laser‐induced fluorescence of indocyanine green: A preliminary experience (2002)

In a prospective, clinical study, the clinical utility of indocyanine green for intraoperative monitoring of free tissue transfer was evaluated. The study comprised 20 surgical patients undergoing elective microsurgical procedures. Indocyanine green angiography was performed intraoperatively, immediately after flap inset, and the operating team was blind to the fluoremetric findings. Thereafter, postoperative monitoring was done exclusively by clinical examination (color, temperature, time for recapillarization, and bleeding after puncture). Final outcome was compared with results of perioperative indocyanine (ICG)-imaging, and classified either as total flap loss, partial flap loss, or successful tissue transplantation. A total of 2 (10%) complications was recorded, and included one partial and one total flap loss. Both complications were detected by intraoperative ICG imaging. Another case of intraoperative subclinical arterial spasm at the place of microvascular anastomosis was revealed by dynamic ICG-videography. This flap did not develop postoperative complications. In conclusion, evaluation of perfusion by ICG imaging is feasible in all kinds of microsurgical flaps, irrespective of the type of tissue. Even though not meeting all the criteria of an ideal monitoring device, significant additional information can be obtained. In this study, cases with arterial spasm, venous congestion, and regional hypoperfusion were revealed by intraoperative ICG-videography. There was a strong correlation between intraoperative findings and clinical outcome.
Unitary PUMA Algorithm for Estimating the Frequency of a Complex Sinusoid (2015)

One-dimensional (1-D) and two-dimensional (2-D) frequency estimation for a single complex sinusoid in white Gaussian noise is a classic signal processing problem with numerous applications. It is revisited here through a new unitary principal-singular-vector utilization modal analysis (PUMA) approach, which is realized in terms of real-valued computations. The 2-D unitary PUMA is first formulated as an iteratively weighted least squares optimization problem. Recognizing that only one iteration is sufficient when 2-D unitary PUMA is initialized using least squares, a computationally attractive closed-form solution is then obtained. A variant of 2-D unitary PUMA is also developed for the 1-D case. Due to the real-valued computations and closed-form expression for the frequency estimate, the unitary PUMA is more computationally efficient than a number of state-of-the-art methods. Furthermore, the asymptotic variances of 1-D and 2-D unitary PUMA estimators are theoretically derived, and numerical results are included to demonstrate the effectiveness of the proposed methods.
Procédé de commande d’un filtre actif parallèle pour réseaux perturbés et filtre actif associé (2016)

Déposant - INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUETitulaire - INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEMandataire - GEVERS &amp; ORES
THE ELECTRICAL CONDUCTIVITIES OF SOME IRON ISONITRILE COMPLEXES1 (1963)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTHE ELECTRICAL CONDUCTIVITIES OF SOME IRON ISONITRILE COMPLEXES1Walter Z. Heldt and Claus D. WeisCite this: J. Phys. Chem. 1963, 67, 6, 1392–1394Publication Date (Print):June 1, 1963Publication History Published online1 May 2002Published inissue 1 June 1963https://pubs.acs.org/doi/10.1021/j100800a528https://doi.org/10.1021/j100800a528research-articleACS PublicationsRequest reuse permissionsArticle Views28Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Short-Term Frequency Regulation and Inertia Emulation Using an MMC-Based MTDC System (2017)

The continuous displacement of conventional power plants by converter-interfaced generation systems reduces the system inertia and may lead to a degradation of the frequency stabili-leon-2757258ty. A supplementary control strategy for multi-terminal dc (MTDC) systems to improve the frequency regulation is presented in this paper. The scenario where the MTDC system cannot resort to the power reserves of either other ac systems or offshore wind farms is particularly studied. The proposed control is able to independently support both the primary frequency regulation and the system inertia by using the capacitive energy of the MTDC grid converters. On the other hand, the reactive power of the converter stations is coordinately controlled to improve the damping of low-frequency electromechanical oscillations. The simultaneous frequency support of the MTDC system and onshore wind farms is also studied and validated in a practical multi-machine power system. Transient and small-signal stability analyses are performed to evaluate and quantify the improvements and the control limitations of the proposed scheme. This enhanced frequency control can increase the system reliability and reduce the required amount of spinning reserve, diminishing the operation costs and allowing to increase the penetration of renewable energy sources.
POLIOMYELITIS AND COXSACKIE VIRUSES IN PARALYTIC POLIOMYELITIS (1951)

Tests for the presence of Coxsackie virus were carried out with specimens of feces and swabbings of the nasopharynx from 20 infants and children suspected of having poliomyelitis who were admitted to a hospital during the summer of 1949 in New York City. Both Coxsackie virus and poliomyelitis virus were recovered from feces collected during the course of illness from each of two children with paralysis. The strains of Coxsackie virus which were isolated from both of these patients were found to be serologically related to Dalldorf's Type 1 Coxsackie virus. The Coxsackie and poliomyelitis viruses which were isolated from one of these patients were found not to be immunologically related to each other. Tests with specimens of serum from both patients showed that one but not the other developed, during convalescence, an increase in the capacity to neutralize the strains of Coxsackie virus which were isolated from them.
An algorithm for the motion control of complex redundant robot manipulators (2002)

A hierarchical controller suitable for the movement coordination of complex and redundant robot manipulators is presented. The algorithm described does not depend on any dynamic system modeling or solving of the inverse kinematical problem. Such knowledge can, however, be taken into account if desired. This is achieved using a performance criterion. With this approach a certain learning behavior can easily be established. This is demonstrated in simulations of the control of a biped locomotive robot system moving in a vertical plane.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Human Monoclonal Antibodies against West Nile Virus Induced by Natural Infection Neutralize at a Postattachment Step (2009)

West Nile virus (WNV) is a neurotropic flavivirus that is now a primary cause of epidemic encephalitis in North America. Studies of mice have demonstrated that the humoral immune response against WNV limits primary infection and protects against a secondary challenge. The most-potent neutralizing mouse monoclonal antibodies (MAbs) recognize an epitope on the lateral ridge of domain III (DIII-lr) of the envelope (E) protein. However, studies with serum from human patients show that antibodies against the DIII-lr epitope comprise, at best, a minor component of the human anti-WNV antibody response. Herein, we characterize in detail two WNV-specific human MAbs, CR4348 and CR4354, that were isolated from B-cell populations of convalescent patients. These MAbs strongly neutralize WNV infection of cultured cells, protect mice against lethal infection in vivo, and yet poorly recognize recombinant forms of the E protein. Instead, CR4348 and CR4354 bind determinants on intact WNV virions and subviral particles in a pH-sensitive manner, and neutralization is altered by mutations at the dimer interface in domain II and the hinge between domains I and II, respectively. CR4348 and CR4354 human MAbs neutralize infection at a postattachment step in the viral life cycle, likely by inhibiting acid-induced fusion within the endosome.
Controlling Light Emission with Photonic Funnels (2022)

We analyze the interaction between a nanoscale emitter and a photonic funnel with a metamaterial core and demonstrate that funnel structures can significantly improve out-coupling efficiency of light as compared with their planar plasmonic counterparts.
Adaptive Immunity and Antigen‐Specific Activation in Obesity‐Associated Insulin Resistance (2015)

Type 2 diabetes mellitus (T2D) is a metabolic disease that is strongly tied to obesity and often preceded by insulin resistance (IR). It has been established that chronic inflammation of hypertrophic adipose tissue depots in obese individuals leads to obesity-associated IR and is mediated by cells of the innate immune system, particularly macrophages. More recently, cells of the adaptive immune system, B and T lymphocytes, have also emerged as important regulators of glucose homeostasis, raising the intriguing possibility that antigen-driven immune responses play a role in disease. In this review, we critically evaluate the roles that various B and T cell subsets play in IR, and then we examine the data suggesting that antigen-driven mechanisms, such as antigen presentation and costimulation, may drive the activity of these lymphocytes.
Sustainability in university campus: options for achieving nearly zero energy goals (2018)

Purpose The purpose of this study was to design a renovation plan for a university campus building (Department of Electrical and Computer Engineering) with the aim to achieve nearly zero energy performance, ensuring a low specific demand (lower than 44 kWh/m 2 ) and a high level of on-site renewable generation (equivalent to more than 20 per cent of the energy demand). Design/methodology/approach The baseline demand was characterized based on energy audits, on smart metering data and on the existing building management system data, showing a recent reduction of the electricity demand owing to some implemented measures. The renovation plan was then designed with two main measures, the total replacement of the actual lighting by LEDs and the installation of a photovoltaic system (PV) with 78.8 kWp coupled with an energy storage system with 100 kWh of lithium-ion batteries. Findings The designed renovation achieved energy savings of 20 per cent, with 27.5 per cent of the consumed energy supplied by the PV system. This will ensure a reduction of the specific energy of the building to only 30 kWh/m 2 , with 42.4 per cent savings on the net-energy demand. Practical implications The designed renovation proves that it is possible to achieve nearly zero energy goals with cost-effective solutions, presenting the lighting renovation and the solar PV generation system a payback of 2.3 and 6.9 years, respectively. Originality/value This study innovated by defining ambitious goals to achieve nearly zero energy levels and presenting a design based on a comprehensive lighting retrofit and PV generation, whereas other studies are mostly based on envelope refurbishment and behaviour changes.
Influence of dissolved organic matter on the complexation of mercury under sulfidic conditions (2007)

The complexation of Hg under sulfidic conditions influences its bioavailability for microbial methylation. Neutral dissolved Hg-sulfide complexes are readily available to Hg-methylating bacteria in culture, and thermodynamic models predict that inorganic Hg-sulfide complexes dominate dissolved Hg speciation under natural sulfidic conditions. However, these models have not been validated in the field. To examine the complexation of Hg in natural sulfidic waters, octanol/water partitioning methods were modified for use under environmentally relevant conditions, and a centrifuge ultrafiltration technique was developed. These techniques demonstrated much lower concentrations of dissolved Hg-sulfide complexes than predicted. Furthermore, the study revealed an interaction between Hg, dissolved organic matter (DOM), and sulfide that is not captured by current thermodynamic models. Whereas Hg forms strong complexes with DOM under oxic conditions, these complexes had not been expected to form in the presence of sulfide because of the stronger affinity of Hg for sulfide relative to its affinity for DOM. The observed interaction between Hg and DOM in the presence of sulfide likely involves the formation of a DOM-Hg-sulfide complex or results from the hydrophobic partitioning of neutral Hg-sulfide complexes into the higher-molecular-weight DOM. An understanding of the mechanism of this interaction and determination of complexation coefficients for the Hg-sulfide-DOM complex are needed to adequately assess how our new finding affects Hg bioavailability, sorption, and flux.
Prediction of cloud-to-ground lightning in the western United States. (2002)

This dissertation focuses specifically on identifying the thermodynamic environment and forcing mechanisms across the western United States that create precipitation systems with lightning. The majority of these convective systems are non-severe. With some thunderstorms, very little precipitation may reach the ground; yet, these "dry" storms spark deadly wildfires in the West every summer.
Congestion Control for Distributed Hash Tables (2006)

Distributed hash tables (DHTs) provide a scalable mechanism for mapping identifiers to socket addresses. As each peer in the network can initiate lookup requests, a DHT has to process concurrently a potentially very large number of requests. In this paper, we look at congestion control for DHTs. Our goal is to control the flow of lookup requests that are routed in the overlay network. We first show that congestion control is essential for certain applications with high lookup rates. We then present two congestion control mechanisms for DHTs and compare their performances in different network conditions