gebhart/patrepeval huggingface dataset:
Smartphone-Based Wound Assessment System for Patients With Diabetes (2014)

Diabetic foot ulcers represent a significant health issue. Currently, clinicians and nurses mainly base their wound assessment on visual examination of wound size and healing status, while the patients themselves seldom have an opportunity to play an active role. Hence, a more quantitative and cost-effective examination method that enables the patients and their caregivers to take a more active role in daily wound care potentially can accelerate wound healing, save travel cost and reduce healthcare expenses. Considering the prevalence of smartphones with a high-resolution digital camera, assessing wounds by analyzing images of chronic foot ulcers is an attractive option. In this paper, we propose a novel wound image analysis system implemented solely on the Android smartphone. The wound image is captured by the camera on the smartphone with the assistance of an image capture box. After that, the smartphone performs wound segmentation by applying the accelerated mean-shift algorithm. Specifically, the outline of the foot is determined based on skin color, and the wound boundary is found using a simple connected region detection method. Within the wound boundary, the healing status is next assessed based on red-yellow-black color evaluation model. Moreover, the healing status is quantitatively assessed, based on trend analysis of time records for a given patient. Experimental results on wound images collected in UMASS-Memorial Health Center Wound Clinic (Worcester, MA) following an Institutional Review Board approved protocol show that our system can be efficiently used to analyze the wound healing status with promising accuracy.
Enhanced Somatic Embryo Induction of a Tree Peony, Paeonia ostii ‘Fengdan’, by a Combination of 6-benzylaminopurine (BA) and 1-naphthylacetic Acid (NAA) (2019)

Somatic embryogenesis is a preferred method for vegetative propagation due to its high propagation efficiency. In this study, zygotic embryos, cotyledons, and hypocotyls of Paeonia ostii ‘Fengdan’ were used as the explant to induce somatic embryogenesis. The results showed that a combination of 0.5 mg·L−1 thidiazuron (TDZ) and 0.5 mg·L−1 2,4-dichlorophenoxyacetic acid (2,4-D) was effective in inducing somatic embryos from the zygotic embryo and cotyledon explants. Hypocotyls only formed somatic embryos on Murashige and Skoog (MS) medium supplemented with both 0.5 mg·L−1 TDZ and 0.5 mg·L−1 1-naphthylacetic acid (NAA). Moreover, the compact callus was effectively produced from zygotic embryo, cotyledon, and hypocotyl explants in medium supplemented with a combination of 3.0 mg·L−1 6-benzylaminopurine (BA) and 1.0 mg·L−1 NAA, and then converted into somatic embryos in the same medium, and the ratio of the explants with embryo induction and number of embryos induced per explant were much higher than those induced by 0.5 mg·L−1 TDZ and either 0.5 mg·L−1 2,4-D or 0.5 mg·L−1 NAA. The MS medium was better than the woody plant medium (WPM) for inducing somatic embryos from zygotic embryo and hypocotyl explants, whereas the WPM was better than the MS medium for somatic embryogenesis induction from cotyledon explants. All of the somatic embryos developed well into mature embryos on their respective media supplemented with both 3.0 mg·L−1 BA and 1.0 mg·L−1 NAA. Overall, the protocols for indirect somatic embryogenesis from zygotic embryo, cotyledon, and hypocotyl of P. ostii ‘Fengdan’ were successfully established, which can greatly facilitate their propagation and breeding processes.
A location- and sharpness-specific tactile electronic skin based on staircase-like nanowire patches (2018)

Human skin can sense an external object in a location-specific manner, simultaneously recognizing whether it is sharp or blunt. Such tactile capability can be achieved in both natural and stretched states. It is impractical to mimic this tactile function of human skin by designing pixelated sensor arrays across our whole curvilinear human body. Here, we report a new tactile electronic skin sensor based on staircase-like vertically aligned gold nanowires (V-AuNWs). With a back-to-back linear or spiral assembly of two staircase structures into a single sensor, we are able to recognize pressure in a highly location-specific manner for both non-stretched and stretched states (up to 50% strain); with a concentric design on the fingertip, we can identify the sharpness of an external object. We believe that our strategy opens up a new route to highly specific second-skin-like tactile sensors for electronic skin (E-skin) applications.
Interstage Injection System for Heavy Duty Industrial Gas Turbine Model 7EA (2001)

This paper describes new methods of cleaning large multistage axial compressors that are the part of Gas Turbine Unit (GTU). Existing, standard method of compressor cleaning are on-line and off-line. In both cases of compressor cleaning clean water and appropriate detergents are mixed to remove dirt deposits from the blade surface. The on-line system is attractive because the cleaning is done when GTU is under full load. The on-line compressor cleaning slows down inevitable dirt depositing. Offline cleaning is much more effective than on-line cleaning. The negative side of off-line cleaning is that GTU must be shut down. In case of large GTU the processes of shut down and start up require significant amount of time. This paper also incorporates the efforts required to install Inter-stage Injection System (IIS) in one GTU in Watson Cogeneration Company (WCC).
For the Record (1994)

No AccessJournal of Speech, Language, and Hearing ResearchLetter to the Editor1 Aug 1994For the RecordA Response to Armson and Kalinowski’s Rebuttal Martin R. Adams, andUniversity of Houston Martin R. Adams University of Houston Google Scholar More articles by this author andUniversity of Houston https://doi.org/10.1044/jshr.3704.815 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationTrack Citations ShareFacebookTwitterLinked In References Adams, M. R. (1984). Laryngeal onset and reaction times of stutterers.In R. F. Curlee & W. H. Perkins (Eds.), Nature and treatment of stuttering: New directions (pp. 89–104). San Diego: College Hill Press. Google Scholar Adams, M. R. (1985). The speech physiology of stutterers: Present status.Seminars in Speech and Language, 6, 177–196. CrossrefGoogle Scholar Armson, J., & Kalinowski, J. (1994). Interpreting results of the fluent speech paradigm in stuttering research: Difficulties in separating cause from effect.Journal of Speech and Hearing Research, 37, 69–82. ASHAWireGoogle Scholar Additional Resources FiguresReferencesRelatedDetails Volume 37Issue 4August 1994Pages: 815-815 Get Permissions Add to your Mendeley library HistoryReceived: Apr 4, 1994Accepted: Apr 18, 1994 Published in issue: Aug 1, 1994 Metrics Topicsasha-topicsasha-article-typesCopyright & PermissionsCopyright © 1994 American Speech-Language-Hearing AssociationPDF downloadLoading ...
Sniper Localization Using Acoustic Asynchronous Sensors (2010)

This paper describes a novel sniper localization method for a network of acoustic sensors. This approach relies only on the time-difference-of-arrival (TDOA) between the muzzle blast and shock wave from multiple single acoustic sensor nodes, as opposed to an array of microphones, relaxing the need for precise time synchronization across the network. This method is also best suited where an array of sensors, on a per-node basis, is not feasible. Results of the sniper localization algorithm using data collected in a field are presented here. Derivation of the Cramer-Rao bound is presented, and the results of the algorithm are compared with the bound.
Specific proteins mediate enhanced osteoblast adhesion on nanophase ceramics (2000)

Osteoblast, fibroblast, and endothelial cell adhesion on nanophase (that is, materials with grain sizes less than 100 nm) alumina, titania, and hydroxyapatite (HA) was investigated using in vitro cellular models. Osteoblast adhesion was significantly (p < 0.01) greater after 4 h on nanophase alumina, titania, and HA than it was on conventional formulations of the same ceramics. In contrast, compared to conventional alumina, titania, and HA, after 4 h fibroblast adhesion was significantly (p < 0.01) less on nanophase ceramics. Examination of the underlying mechanism(s) of cell adhesion on nanophase ceramics revealed that these ceramics adsorbed significantly (p < 0.01) greater quantities of vitronectin, which, subsequently, may have contributed to the observed select enhanced adhesion of osteoblasts. Select enhanced osteoblast adhesion was independent of surface chemistry and material phase but was dependent on the surface topography (specifically on grain and pore size) of nanophase ceramics. The capability of synthesizing and processing nanomaterials with tailored (through, for example, specific grain and pore size) structures and topographies to control select subsequent cell functions provides the possibility of designing the novel proactive biomaterials (that is, materials that elicit specific, timely, and desirable responses from surrounding cells and tissues) necessary for improved implant efficacy.
Molecularly Tunable Fluorescent Quantum Defects (2016)

We describe the chemical creation of molecularly tunable fluorescent quantum defects in semiconducting carbon nanotubes through covalently bonded surface functional groups that are themselves nonemitting. By variation of the surface functional groups, the same carbon nanotube crystal is chemically converted to create more than 30 distinct fluorescent nanostructures with unique near-infrared photoluminescence that is molecularly specific, systematically tunable, and significantly brighter than that of the parent semiconductor. This novel exciton-tailoring chemistry readily occurs in aqueous solution and creates functional defects on the sp(2) carbon lattice with highly predictable C-C bonding from virtually any iodine-containing hydrocarbon precursor. Our new ability to control nanostructure excitons through a single surface functional group opens up exciting possibilities for postsynthesis chemical engineering of carbon nanomaterials and suggests that the rational design and creation of a large variety of molecularly tunable quantum emitters-for applications ranging from in vivo bioimaging and chemical sensing to room-temperature single-photon sources-can now be anticipated.
Identification of Cross-Reactive Norovirus CD4+ T Cell Epitopes (2020)

Immune responses and the components of protective immunity following norovirus infection in humans are poorly understood. Although antibody responses following norovirus infection have been partially characterized, T cell responses in humans remain largely undefined. In contrast, T cells have been shown to be essential for viral clearance of mouse norovirus (MNV) infection. In this paper, we demonstrate that CD4+ T cells secrete gamma interferon (IFN-γ) in response to stimulation with MNV virus-like particles (VLPs) after MNV infection, supporting earlier reports for norovirus-infected mice and humans. Utilizing this model, we immunized mice with alphavirus vectors (Venezuelan equine encephalitis [VEE] virus replicon particles [VRPs]) expressing Norwalk virus (NV) or Farmington Hills virus (FH) virus-like particles to evaluate T cell epitopes shared between human norovirus strains. Stimulation of splenocytes from norovirus VRP-immunized mice with overlapping peptides from complete libraries of the NV or FH capsid proteins revealed specific amino acid sequences containing T cell epitopes that were conserved within genoclusters and genogroups. Immunization with heterologous norovirus VRPs resulted in specific cross-reactive IFN-γ secretion profiles following stimulation with NV and FH peptides in the mouse. Identification of unique strain-specific and cross-reactive epitopes may provide insight into homologous and heterologous T cell-mediated norovirus immunity and provide a platform for the study of norovirus-induced cellular immunity in humans.
Three Novel Cytochalasins X, Y, and Z from Pseudeurotium zonatum (2002)

Fermentation of Pseudeurotium zonatum led to the isolation of the known cytochalasin G (1) and three new cytochalasins, X, Y, and Z (2-4). These four compounds are the only naturally occurring cytochalasins reported to date that contain an indole-substituted perhydroisoindol-1-one fused with an 11-membered macrocycle.
Acute Kidney Injury Following Resuscitative Endovascular Balloon Occlusion of the Aorta: A Systematic Review (2018)

Background: Resuscitative endovascular balloon occlusion of the aorta (REBOA) is an emergent technology for the treatment of non-compressible torso hemorrhage (NCTH). While aortic occlusion (AO) above the site of hemorrhage provides hemostasis and time for surgical intervention, ischemia-reperfusion injury to the kidneys is a known complication. We aimed to report the incidence and factors associated with acute kidney injury (AKI) following AO in patients with NCTH or in similar porcine models. Methods: We searched Pubmed (MEDLINE), Embase, Scopus, and ProQuest Dissertations &amp; Theses from inception to July 2017. We included original studies of trauma patients with NCTH treated with REBOA, or similar porcine studies that included renal parameters, excluding case reports and case series. After duplicate removal, full texts of studies retrieved via the search strategy were evaluated by two authors. Renal parameters (e.g., creatinine concentration, urine output, histopathology) were extracted. Quality of the evidence and risk of bias were assessed.Results: Twelve out of 2,100 records were included (three trauma patients, nine porcine studies). While one out of three human reports described AO in Zone 1, all swine publications reported Zone 1. All human studies reported renal damage. There were nonetheless inconsistencies in definitions used. Evidence of AKI was reported in three out of nine swine studies. Conclusions: Consistent reporting of AKI incidence is lacking from human clinical studies of AO in NCTH trauma patients. While comorbidities in trauma patients may contribute to AKI, animal models support the association between AO and AKI. As REBOA is growing in popularity as a therapy for NCTH, further studies determining factors associated with the AKI are needed.
Stereochemistry of the alkaloid gitingensine (1967)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStereochemistry of the alkaloid gitingensineGertrudes Aguilar-Santos, Elvira Santos, and Pierre CrabbeCite this: J. Org. Chem. 1967, 32, 8, 2642–2644Publication Date (Print):August 1, 1967Publication History Published online1 May 2002Published inissue 1 August 1967https://pubs.acs.org/doi/10.1021/jo01283a069https://doi.org/10.1021/jo01283a069research-articleACS PublicationsRequest reuse permissionsArticle Views62Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
miR-153 suppresses IDO1 expression and enhances CAR T cell immunotherapy (2018)

These findings indicate that miR-153 inhibits IDO1 expression in colon cancer cells and is a tumor-suppressive miRNA that enhances CAR T cell immunotherapy. This study supports the combinatorial use of IDO1 inhibitors and CAR T cells in treating solid tumors.
Effect of Model Sorptive Phases on Phenanthrene Biodegradation: Different Enrichment Conditions Influence Bioavailability and Selection of Phenanthrene-Degrading Isolates (2000)

The sorption of organic contaminants by natural organic matter (NOM) often limits substrate bioavailability and is an important factor affecting microbial degradation rates in soils and sediments. We hypothesized that reduced substrate bioavailability might influence which microbial assemblages are responsible for contaminant degradation under enrichment culture conditions. Our primary goal was to characterize enrichments in which different model organic solid phases were used to establish a range of phenanthrene bioavailabilities for soil microorganisms. Phenanthrene sorption coefficients (expressed as log K(D) values) ranged from 3.0 liters kg(-1) for Amberlite carboxylic acid cation-exchange resin (AMB) to 3.5 liters kg(-1) for Biobeads polyacrylic resin (SM7) and 4.2 liters kg(-1) for Biobeads divinyl benzene resin (SM2). Enrichment cultures were established for control (no sorptive phase), sand, AMB, SM7, and SM2 treatments by using two contaminated soils (from Dover, Ohio, and Libby, Mont.) as the initial inocula. The effects of sorption by model phases on the degradation of phenanthrene were evaluated for numerous transfers in order to obtain stable microbial assemblages representative of sorptive and nonsorptive enrichment cultures and to eliminate the effects of the NOM present in the initial inoculum. Phenanthrene degradation rates were similar for each soil inoculum and ranged from 4 to 5 micromol day(-1) for control and sand treatments to approximately 0.4 micromol day(-1) in the presence of the SM7 sorptive phase. The rates of phenanthrene degradation in the highly sorptive SM2 enrichment culture were insignificant; consequently, stable microbial populations could not be obtained. Bacterial isolates obtained from serial dilutions of enrichment culture samples exhibited significant differences in rates of phenanthrene degradation performed in the presence of SM7, suggesting that enrichments performed in the presence of a sorptive phase selected for different microbial assemblages than control treatments containing solid phase phenanthrene.
Tailored metallacarboranes as mediators for boosting the stability of carbon-based aqueous supercapacitors (2017)

The addition of a tailored metallacarborane to a commercial AC allows using supercapacitors (in 0.5 M Na<sub>2</sub>SO<sub>4</sub> electrolyte) at 2.2 V.
Nicotine increases initial blood flow responses to local heating of human non‐glabrous skin (2004)

Nicotine affects the regulation of skin blood flow (SkBF), but the mechanisms involved are not well understood. We tested the hypothesis that acute exposure to nicotine inhibits both the initial neurally mediated component and the later sustained component of SkBF responses to local heating of non-glabrous skin in humans. SkBF (measured by laser-Doppler) responses to local heating of forearm skin from 32 to 42 degrees C were measured in 11 chronic smokers. Heating occurred at one site over 15 min (RAMP) and over 90 s (STEP) at another site, and was maintained for an additional 30 min. STEP heating was also applied to a site pretreated with bretylium via iontophoresis to inhibit noradrenergic neurotransmission. Responses were measured before and after acute administration of nicotine via cigarettes or nasal spray in two experimental sessions. Nicotine decreased resting skin blood flow (P < 0.05); this response was inhibited by bretylium. During RAMP, nicotine increased the initial SkBF at 42 degrees C (by approximately 12%, P < 0.05). For STEP, nicotine increased the initial peak response (by approximately 25%, P < 0.05), and decreased the sustained plateau value (by approximately 10%, P < 0.05). In skin pretreated with bretylium, the increase caused by nicotine in the initial peak value persisted, but the plateau value was not different from pre-nicotine. These data suggest that in abstinent cigarette smokers, nicotine augments initial responses to both gradual and rapid non-painful heating of non-glabrous skin by sensitizing the sensory nerves that mediate the axon reflex associated with rapid vasodilatation. In contrast, nicotine decreases SkBF responses to prolonged heating by activating noradrenergic nerves.
Characterization of particles by modulated dynamic light scattering. II. Experiment (1994)

In an earlier paper we described the theoretical foundations of modulated dynamic light scattering (MDLS) and indicated how these methods can be implemented in the characterization of particles. In this paper we illustrate the range of application of MDLS methods by describing eight types of MDLS experiments we have performed. In addition to illustrating the range of application of MDLS methods, the results of these experiments validate our theoretical predictions. The experiments were done with an MDLS apparatus in which the requisite modulation is produced by frequency-biasing two intersecting laser beams with acousto-optic modulators. Measurements were made by introducing a single sample particle into the intersection volume of the two beams and processing the scattered light signal from the particle. Data from these experiments typically provide detailed records of the translational and/or rotational Brownian motion for one or more single particles suspended in a fluid medium. Dynamic particle properties are inferred by comparing measured results with theoretical results based on models of Brownian motion. Described MDLS method experiments include (a) simultaneous measurement of the translational diffusion coefficient and velocity component of particles suspended in air; (b) simultaneous measurement of the translational and rotational Brownian motion of hematite ellipsoids and spindles with submicrometer dimensions suspended in water; (c) determination of the diameters and slip correction factors of micrometer-sized spheres suspended in air; (d) determination of the precision of the present MDLS apparatus for finding sphere diameters; (e) precise measurement of sphere diameters; (f) simultaneous measurement of the mass and friction coefficient of a particle suspended in air and verification of predicted effects of particle inertia on Brownian translation and rotation; (g) measurement of translational Brownian displacement distributions; and (h) determination of precision vs measurement time for an MDLS method.
Dynamics of Vibrational Predissociation of (C2H4)2 and of IR‐Multiphoton Excitation of SF6 (1988)

Abstract High resolution measurements are discussed which indicate two decay channels for IR‐excited (C 2 H 4 ) 2 ; for cold dimers, from observed linewidths a 45 ns lifetime is derived after which the products are in their vibrational ground state. For hot dimers a many orders of magnitude shorter lifetime is indicated after which one of the product monomers is found in an excited v 10 level. For highly excited SF 6 (〈 n 〉 = 4 ÷ 5) narrow spectral features are observed attributed to rapid adiabatic passage processes. The IVR lifetime of the excited state is found to be longer than about 1 ms.
Untersuchungen zum Mechanismus einer Olefinierungsreaktion von Aldehyden zu 1,1‐Bis(trifluormethyl)alkenen (1989)

Abstract 1,1‐Bis(trifluormethyl)olefine 3 werden aus Aldehyden, 2,2‐Dichlorhexafluorpropan ( 1 ) und Triphenylphosphan erhalten. Der Mechanismus dieser Olefinierungsreaktion wird untersucht, und es wird gezeigt, daß es sich nicht um eine Wittig‐ sondern um eine Knoevenagel‐analoge Reaktion handelt. Ketone reagieren mit 1 und Triphenylphosphan nur dann zu den Olefinen 3 , wenn sie durch eine CF 3 ‐Gruppe aktiviert sind. Chlor‐substituierte Ketone, z. B. 1,1,1‐Trichloraceton oder Hexachloraceton, können nicht zu den entsprechenden 1,1‐Bis(trifluormethyl)olefinen umgesetzt werden. Hexachloraceton reagiert mit Triphenylphosphan überwiegend zu Perchlorallen ( 24 ), das quantitativ zu Perchlor‐1,2‐dimethylencyclobutan ( 25 ) dimerisiert.