gebhart/patrepeval huggingface dataset:
Ecological Democracy, Just Transitions and a Political Ecology of Design (2019)

This article takes stock of the project of ecological democracy, a project that has been central to debates in Environmental Values since the late 1990s. Whilst we can identify quite distinct articulations of eco-democratic thinking emerging out of the fields of green political theory, postcolonial/feminist political ecology and science studies/radical geography, it is argued that these discussions have reached something of an impasse of late following the rise of climate scepticism, authoritarian populisms and technocratic eco-modernisms. Resurgent eco-authoritarian impulses and the hankering for a ‘green leviathan’, a climate Lenin or a ‘dictatorship of the sustainment’ to resolve our climate crisis make it more important than ever to affirm the need for just, rapid and democratic post-carbon transitions. The article goes on to outline how emerging discussions in radical design studies focused on redirective practice in conjunction with a revived eco-socialist focus on labour-focused political ecologies might open up different possibilities for a materialist re-grounding of ecodemocratic discussions. It is suggested that a political ecology of design embedded in public institutions, the workplace and civil society could possibleyreground a more substantive vision of ecological democracy but also allow us to think about the forms of creative labour that could drive the just transition.
Increased Influenza Vaccination of Healthcare Workers at a Pediatric Cancer Hospital: Results of a Comprehensive Influenza Vaccination Campaign (2006)

A comprehensive influenza vaccination campaign improved vaccination rates among healthcare workers with direct patient care responsibilities from 45% during the 2003-2004 influenza season to 80% during the 2004-2005 season. A strategy of weekly feedback to unvaccinated employees was the most important factor in enhancing the rate of vaccination acceptance and was particularly effective among the nursing staff.
Identification of an oxidative stress-sensitive protein from Campylobacter jejuni, homologous to rubredoxin oxidoreductase/rubrerythrin (2004)

An oxidative stress-sensitive protein was found in the microaerophile Campylobacter jejuni. A novel 27-kDa protein was found to decrease concomitantly with a decrease in viability from either exogenous H(2)O(2) stress or endogenous oxidative stresses in aerobic conditions. Sequence analyses revealed that the 27-kDa protein was identical to Cj0012c in C. jejuni NCTC11168 and its deduced 215 amino acid sequence has similarity to two non-heme iron proteins found in other bacteria, rubredoxin oxidoreductase (Rbo) and rubrerythrin (Rbr). Thus, we designated the protein as Rrc (Rbo/Rbr-like protein of C. jejuni). In H(2)O(2)-treated cells, Western blot analysis showed some bands smaller than Rrc, and RT-PCR showed similar expression of Rrc mRNA to the control without treatment, suggesting that the sensitive response of Rrc to oxidative stress is due to degradation of the protein.
Image segmentation, evaluation, and applications (2010)

This thesis aims to advance research in image segmentation by developing robust techniques for evaluating image segmentation algorithms. The key contributions of this work are as follows. First, we investigate the characteristics of existing measures for supervised evaluation of automatic image segmentation algorithms. We show which of these measures is most effective at distinguishing perceptually accurate image segmentation from inaccurate segmentation. We then apply these measures to evaluating four state-of-the-art automatic image segmentation algorithms, and establish which best emulates human perceptual grouping. Second, we develop a complete framework for evaluating interactive segmentation algorithms by means of user experiments. Our system comprises evaluation measures, ground truth data, and implementation software. We validate our proposed measures by showing their correlation with perceived accuracy. We then use our framework to evaluate four popular interactive segmentation algorithms, and demonstrate their performance. Finally, acknowledging that user experiments are sometimes prohibitive in practice, we propose a method of evaluating interactive segmentation by algorithmically simulating the user interactions. We explore four strategies for this simulation, and demonstrate that the best of these produces results very similar to those from the user experiments.
Thoracic aortic surgery with moderate circulatory arrest and cold selective antegrade cerebral perfusion: A multivariate analysis in elective patients (2008)

Introduction: This study was undertaken to identify pre and perioperative risk factors on mortality and permanent (PND) as well as temporary neurological dysfunction (TND).
Cytokinins: Metabolism and Biological Activity of N6-(Δ2-Isopentenyl)adenosine and N6-(Δ2-Isopentenyl)adenine in Tobacco Cells and Callus (1977)

The cytokinin, N(6)-(Delta(2)-isopentenyl)adenine, is found to be at least 3.3 times as active as N(6)-(Delta(2)-isopentenyl)adenosine in promoting the growth of cytokinin-requiring tobacco (Nicotiana tabacum) callus. Absorption rates of N(6)-(Delta(2)-isopentenyl)adenine and N(6)-(Delta(2)-isopentenyl)adenosine by tobacco cells in liquid suspension do not differ significantly. In these cells, N(6)-(Delta(2)-isopentenyl)adenosine-5'-monophosphate, di-, and triphosphate are synthesized in both cases, but 7-glucosylation occurs significantly only with N(6)-(Delta(2)-isopentenyl)adenine, protecting thereby its N(6)-isopentenyl side chain from cleavage. Degradation by N(6)-side chain removal appears to be intense, leading to the formation of adenine, adenosine, and adenylic nucleotides. Thus, it is suggested that N(6)-(Delta(2)-isopentenyl)adenine-7-glucoside is a protected or storage form of the cytokinin which could account for the higher biological activity of N(6)-(Delta(2)-isopentenyl)adenine than of N(6)-(Delta(2)-isopentenyl)adenosine.
Interactive Source Coding for Function Computation in Collocated Networks (2012)

A problem of interactive function computation in a collocated network is studied in a distributed block source coding framework. With the goal of computing samples of a desired function of sources at the sink, the source nodes exchange messages through a sequence of error-free broadcasts. For any function of independent sources, a computable characterization of the set of all feasible message coding rates—the rate region—is derived in terms of single-letter information measures. In the limit as the number of messages tends to infinity, the infinite-message minimum sum rate, viewed as a functional of the joint source probability mass function, is characterized as the least element of a partially ordered family of functionals having certain convex-geometric properties. This characterization leads to a family of lower bounds for the infinite-message minimum sum rate and a simple criterion to test the optimality of any achievable infinite-message sum rate. An iterative algorithm for evaluating the infinite-message minimum sum-rate functional is proposed and is demonstrated through an example of computing the minimum function of three Bernoulli sources. Based on the characterizations of the rate regions, it is shown that when computing symmetric functions of binary sources, the sink will inevitably learn certain additional information that is not demanded in computing the function. This conceptual understanding leads to new improved bounds for the minimum sum rate. The new bounds are shown to be orderwise better than those based on cut-sets as the network scales. The scaling law of the minimum sum rate is explored for different classes of symmetric functions and source parameters.
Peer-to-peer physician feedback improves adherence to blood transfusion guidelines in the surgical intensive care unit (2015)

Therapeutic/care management study, level IV.
Dysregulated miR-671-5p / CDR1-AS / CDR1 / VSNL1 axis is involved in glioblastoma multiforme (2015)

MiR-671-5p is encoded by a gene localized at 7q36.1, a region amplified in human glioblastoma multiforme (GBM), the most malignant brain cancer. To investigate whether expression of miR-671-5p were altered in GBM, we analyzed biopsies from a cohort of forty-five GBM patients and from five GBM cell lines. Our data show significant overexpression of miR-671-5p in both biopsies and cell lines. By exploiting specific miRNA mimics and inhibitors, we demonstrated that miR-671-5p overexpression significantly increases migration and to a less extent proliferation rates of GBM cells. Through a combined in silico and in vitro approach, we identified CDR1-AS, CDR1, VSNL1 as downstream miR-671-5p targets in GBM. Expression of these genes significantly decreased both in GBM biopsies and cell lines and negatively correlated with that of miR-671-5p. Based on our data, we propose that the axis miR-671-5p / CDR1-AS / CDR1 / VSNL1 is functionally altered in GBM cells and is involved in the modification of their biopathological profile.
Sampling genotypes in large pedigrees with loops (2001)

Markov chain Monte Carlo (MCMC) methods have been proposed to overcome computational problems in linkage and segregation analyses. This approach involves sampling genotypes at the marker and trait loci. Scalar-Gibbs is easy to implement, and it is widely used in genetics. However, the Markov chain that corresponds to scalar-Gibbs may not be irreducible when the marker locus has more than two alleles, and even when the chain is irreducible, mixing has been observed to be slow. These problems do not arise if the genotypes are sampled jointly from the entire pedigree. This paper proposes a method to jointly sample genotypes. The method combines the Elston-Stewart algorithm and iterative peeling, and is called the ESIP sampler. For a hypothetical pedigree, genotype probabilities are estimated from samples obtained using ESIP and also scalar-Gibbs. Approximate probabilities were also obtained by iterative peeling. Comparisons of these with exact genotypic probabilities obtained by the Elston-Stewart algorithm showed that ESIP and iterative peeling yielded genotypic probabilities that were very close to the exact values. Nevertheless, estimated probabilities from scalar-Gibbs with a chain of length 235 000, including a burn-in of 200 000 steps, were less accurate than probabilities estimated using ESIP with a chain of length 10 000, with a burn-in of 5 000 steps. The effective chain size (ECS) was estimated from the last 25 000 elements of the chain of length 125 000. For one of the ESIP samplers, the ECS ranged from 21 579 to 22 741, while for the scalar-Gibbs sampler, the ECS ranged from 64 to 671. Genotype probabilities were also estimated for a large real pedigree consisting of 3 223 individuals. For this pedigree, it is not feasible to obtain exact genotype probabilities by the Elston-Stewart algorithm. ESIP and iterative peeling yielded very similar results. However, results from scalar-Gibbs were less accurate.
CCDC 808490: Experimental Crystal Structure Determination (2011)

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
A role for lectin interactions during human neutrophil aggregation. (1994)

We have recently reported that neutrophil aggregation is dependent on both L-selectin and the beta 2-integrin Mac-1, raising the possibility that carbohydrate interactions play a role in aggregation. We used mono- and polysaccharides known to inhibit L-selectin-dependent adhesion of lymphocytes to high endothelial venules to test whether these carbohydrates could inhibit neutrophil aggregation. Similar types and concentrations of carbohydrates found by others to inhibit lymphocyte adhesion were effective in blocking neutrophil aggregation. Thus, nanomolar concentrations of the polysaccharides dextran sulfate (m.w. 500,000) and fucoidan inhibited aggregation, whereas dermatan sulfate, alpha-carrageenan, and dextran sulfate (m.w. 5,000) showed no inhibition. All of the phosphorylated monosaccharides tested inhibited aggregation with ED50 values between 8 and 17 mM, the most potent being mannose-6-phosphate and fucose-1-phosphate. The nonphosphorylated monosaccharides glucose and fucose were noninhibitory. The inhibitory effects of fucoidan or dextran sulfate (m.w. 500,000) did not appear to be due to altered regulation of L-selectin after stimulation because fucoidan reduced the rate of L-selectin shedding, whereas dextran sulfate had no effect compared with control. Neither carbohydrate inhibited the binding of formyl peptide to its receptor. However, carbohydrates were able to compete with mAb binding to a number of known leukocyte adhesion proteins. We used endotoxin pretreatment to create L-selectin-deficient neutrophils to study the minimum adhesive requirements for aggregation using two-color fluorescence flow cytometry. Our results implicate a lectinlike contribution to neutrophil aggregation, and suggest that L-selectin is the molecule that mediates the carbohydrate-dependent adhesive event.
Self‐Limiting Galvanic Growth of MnO2 Monolayers on a Liquid Metal—Applied to Photocatalysis (2019)

Abstract Liquid metals offer unprecedented chemistry. Here it is shown that they can facilitate self‐limiting oxidation processes on their surfaces, which enables the growth of metal oxides that are atomically thin. This claim is exemplified by creating atomically thin hydrated MnO 2 using a Galvanic replacement reaction between permanganate ions and a liquid gallium–indium alloy (EGaIn). The “liquid solution”–“liquid metal” process leads to the reduction of the permanganate ions, resulting in the formation of the oxide monolayer at the interface. It is presented that under mechanical agitation liquid metal droplets are established, and simultaneously, hydrated gallium oxides and manganese oxide sheets delaminate themselves from the interfacial boundaries. The produced nanosheets encapsulate a metallic core, which is found to consist of solid indium only, with the full migration of gallium out of the droplets. This process produces core/shell structures, where the shells are made of stacked atomically thin nanosheets. The obtained core/shell structures are found to be an efficient photocatalyst for the degradation of an organic dye under simulated solar irradiation. This study presents a new research direction toward the modification and functionalization of liquid metals through spontaneous interfacial redox reactions, which has implications for many applications beyond photocatalysis.
Cyclic GMP-Induced Reduction in Cardiac Myocyte Function Is Partially Mediated by Activation of the Sarcoplasmic Reticulum Ca<sup>2+</sup>-ATPase (2002)

We tested the hypothesis that the mechanism through which cyclic GMP reduces cardiac function is mediated by activation of the sarcoplasmic reticulum Ca(2+)-ATPase (SERCA). Cardiac myocytes were isolated from New Zealand white rabbits (n = 11). Individual ventricular cells were stimulated by electrical field stimulation. The maximal rate of cell shortening and percentage shortening were measured with a video edge detector. Thapsigargin (10(-8) mol/l) was used as a specific inhibitor of SERCA. When 8-bromo-cyclic GMP (8-Br-cGMP, 10(-7, -6, -5) mol/l) was added to cells, the maximal rate of myocyte shortening (R(max), microm/s) and percentage shortening were both decreased in a concentration-dependent manner. R(max) decreased 27% from 117 +/- 12 at baseline to 85.2 +/- 13 when 10(-5) mol/l of 8-Br-cGMP was present, and percent shortening was reduced 28% from 6.0 +/- 0.5 to 4.3 +/- 0.5%. Thapsigargin (10(-8) mol/l) increased the maximal rate of myocyte shortening and percent shortening. Addition of thapsigargin prior to 8-Br-cGMP reduced the negative effects of cGMP on myocyte function. The percent shortening decreased only 11% and R(max) decreased 14% with 10(-5) mol/l 8-Br-cGMP, which was not significant. Cyclopiazonic acid, another SERCA inhibitor, was also used to test whether 8-Br-cGMP reduced myocyte function through SERCA. The results were similar to those when thapsigargin was used. These results indicated that the cyclic GMP-induced reduction in cardiac myocyte function was partially mediated through the action of the sarcoplasmic reticulum Ca(2+)-ATPase.
Solid Particle Erosion Resistance of Thermally Sprayed Functionally Graded Polymer/Ceramic Coatings (2004)

Abstract The use of polymer matrix composites [PMC's] in the gas flow path of advanced turbine engines offers significant benefits for aircraft engine performance, but their useful lifetime is limited by their poor erosion resistance. HVOF and flame sprayed polymer/cermet functionally graded coatings based on a polyimide matrix filled with varying volume fractions of WC-Co are being investigated to improve the erosion and oxidation resistance of polymer matrix composites. A study of the coating's effectiveness as erosion barriers was accomplished through a statistical analysis of the results of solid particle erosion testing of coated and uncoated PMC samples using a design of experiments [DoE] approach. Three coating systems and a control were evaluated in a randomized test matrix. The coatings were tested at room temperature and 250 °C, using an alumina erodent impacting the coatings at a speed of 100 m/s at angles of 20° and 90°. Erosion volume loss at 250 °C was approximately twice than at room temperature, but the maximum erosion volume loss did not exceed 0.30 mm3 at the elevated temperature. In general, as the angle of incidence of the eroding material increased from 20 degrees to 90 degrees the volume loss increased.
The effects of static and intermittent compression on nitric oxide production in articular cartilage explants (2001)

Nitric oxide (NO) production and NO synthase (NOS) expression are increased in osteoarthritis and rheumatoid arthritis, suggesting that NO may play a role in the destruction of articular cartilage. To test the hypothesis that mechanical stress may increase NO production by chondrocytes, we measured the effects of physiological levels of static and intermittent compression on NOS activity, NO production, and NOS antigen expression by porcine articular cartilage explants. Static compression significantly increased NO production at 0.1 MPa stress for 24 h (P < 0.05). Intermittent compression at 0.5 Hz for 6 h followed by 18 h recovery also increased NO production and NOS activity at 1.0 MPa stress (P < 0.05). Intermittent compression at 0.5 Hz for 24 h at a magnitude of 0.1 or 0.5 MPa caused an increase in NO production and NOS activity (P < 0.05). Immunoblot analysis showed stress-induced upregulation of NOS2, but not NOS1 or NOS3. There was no loss in cell viability following any of the loading regimens. Addition of 2 mM 1400 W (a specific NOS2 inhibitor) reduced NO production by 51% with no loss of cell viability. These findings indicate that NO production by chondrocytes is influenced by mechanical compression in vitro and suggest that biomechanical factors may in part regulate NO production in vivo.
Metabolic effects in a murine cachexia model (1990)

Conference Article| February 01 1990 Metabolic effects in a murine cachexia model MICHAEL J. TISDALE MICHAEL J. TISDALE 1C.R.C. Experimental Chemotherapy Group, Pharmaceutical Sciences Institute, Aston University, Birmingham B4 7ET, U.K. Search for other works by this author on: This Site PubMed Google Scholar Author and article information Publisher: Portland Press Ltd Received: July 20 1989 Online ISSN: 1470-8752 Print ISSN: 0300-5127 © 1990 Biochemical Society1990 Biochem Soc Trans (1990) 18 (1): 83–84. https://doi.org/10.1042/bst0180083 Article history Received: July 20 1989 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Citation MICHAEL J. TISDALE; Metabolic effects in a murine cachexia model. Biochem Soc Trans 1 February 1990; 18 (1): 83–84. doi: https://doi.org/10.1042/bst0180083 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search Keywords: TPN, total parenteral nutrition, TNF, tumour necrosis factor This content is only available as a PDF. © 1990 Biochemical Society1990 Article PDF first page preview Close Modal You do not currently have access to this content.
Electron Paramagnetic Resonance: Elementary Theory and Practical Applications (1995)

Basic Principles of Electron Paramagnetic Resonance Magnetic Interactions Between Particles Isotropic Hyperfine Effects in EPR Spectra g-Anisotropy in Solids Hyperfine Anisotropy in Solids Systems with More than One Unpaired Electron Paramagnetic Species in Gas Phase Transition-Group Ions The Interpretation of EPR Parameters Relaxation Times, Linewidths and Kinetic Phenomena Time-Dependent Excitation of Spins Double-Resonance Techniques Other Topics.
The coupling of light-emitting diodes to optical fibers using sphere lenses (1975)

The use of a truncated sphere of high-refractive-index material is proposed as a lens designed to improve the coupling efficiency between a light-emitting-diode source and an optical fiber. A method of calculating the coupling efficiency for such lens systems is described. Numerical results for the variation of efficiency with lens parameters are presented and discussed for coupling to a fiber bundle with a numerical aperture of 0.14. Improvements of two orders of magnitude in the coupling efficiency over that attainable with the close coupling geometry are predicted.
Adaptive modulation system with variable coding rate concatenated code for high quality multi-media communication systems (2002)

This paper proposes an adaptive modulation system with a concatenated code (AMS-CC) for land mobile communications to achieve high quality, high bit rate transmission in Rayleigh fading environments. The proposed system adaptively controls the coding rate of the inner convolutional code, symbol rate, and modulation level according to the instantaneous fading channel conditions. The performances in Rayleigh fading environments are evaluated theoretically and by computer simulation. The results show that the proposed system can realize higher quality transmission without the degradation in average bit rate compared to conventional adaptive modulation systems.
Multicenter phase 2 study of patupilone for recurrent or progressive brain metastases from non–small cell lung cancer (2015)

This is the first prospective study of chemotherapy for recurrent brain metastases from NSCLC. In this population, patupilone demonstrated activity in heavily treated patients.
Supplemental Movie 3 from Full-Length Semaphorin-3C Is an Inhibitor of Tumor Lymphangiogenesis and Metastasis (2023)

&lt;p&gt;Supplemental Movie 3. A time lapse movie of proliferating lymphatic endothelial cells (LEC).&lt;/p&gt;