gebhart/patrepeval huggingface dataset:
Cell-Free Massive MIMO with Radio Stripes and Sequential Uplink Processing (2020)

Cell-free Massive MIMO (mMIMO) is envisaged to be a next-generation technology beyond 5G with its high spectral efficiency and superior spatial diversity as compared to that of conventional MIMO technology. The main principle is that many distributed access points (APs) cooperate to simultaneously serve all the users within the network without creating cell boundaries. This paper considers the uplink of a cell-free mMIMO system utilizing the radio stripe network architecture. We propose a novel sequential processing algorithm with normalized linear minimum mean square error (N-LMMSE) combining at every AP. This algorithm enables interference suppression in cell-free mMIMO while keeping the cost and front-haul requirements low. The spectral efficiency of the proposed algorithm is computed and analyzed. We conclude that it provides an attractive trade-off between low front-haul requirements and high spectral efficiency.
Cell and Material Interface (2015)

A significant portion of biomedical applications necessitates the establishment of an interface between the cells of the patient and the components of the device. In many cases, such as in implants and engineered tissues, the interaction of the cells with the biomaterial is one of the main determinants of the success of the system. Cell and Material Interface: Advances in Tissue Engineering, Biosensor, Implant, and Imaging Technologies explores this interaction and its control at length scales ranging from the nano to the macro. Featuring contributions from leading molecular biologists, chemists, and material scientists, this authoritative reference: Presents practical examples of cell and material interface-based applications Reflects the interdisciplinary nature of bioengineering, covering topics such as biosensing, immunology, and controlled delivery Explains the role of the cell and material interface in the context of cardiac and skin tissue engineering, nanoparticles, natural polymers, and more Cell and Material Interface: Advances in Tissue Engineering, Biosensor, Implant, and Imaging Technologies addresses concepts essential to biomaterial production methods and cell and material interactions. The book provides a solid starting point for elucidating and exploiting the different aspects of cellular interactions with materials for biomedical engineering.
Molecular cloning and physical and functional characterization of the Salmonella typhimurium and Salmonella typhi galactose utilization operons (1990)

The chromosomally encoded galactose utilization (gal) operons of Salmonella typhimurium and S. typhi were each cloned on similar 5.5-kilobase HindIII fragments into pBR322 and were identified by complementation of Gal- Escherichia coli strains. Restriction endonuclease analyses indicated that these Salmonellae operons share considerable homology, but some heterogeneities in restriction sites were observed. Subcloning and exonuclease mapping experiments showed that both operons have the same genetic organization as that established for the E. coli gal operon (i.e., 5' end, promoter, epimerase, transferase, kinase, and 3' end). Two gal operator regions (oE and oI) of S. typhimurium, identified by repressor titration in an E. coli superrepressor [galR(Sup)] mutant, were sequenced and found to flank the promoter region. This promoter region is identical to the -10 and -35 regions of the E. coli gal operon. Minicell studies demonstrated that the three gal structural genes of S. typhimurium encode separate polypeptides of 39 kilodaltons (kDa) (epimerase, 337 amino acids [aa's]), 41 kDa (transferase, 348 aa's), and 43 kDa (kinase, 380 aa's). Despite functional and organizational similarities, DNA sequence analysis revealed that the S. typhimurium gal genes show less than 70% homology to the E. coli gal operon. Because of codon degeneracy, the deduced amino acid sequences of these polypeptides are highly conserved (greater than 90% homology) as compared with those of the E. coli gal enzymes. These studies have defined basic genetic parameters of the gal genes of two medically important Salmonella species, and our findings support the hypothesized divergent evolution of E. coli and Salmonella spp. from a common ancestral parent bacterium.
Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines (2006)

A comprehensive analysis of the TP53 gene and its protein status was carried out on a panel of 56 colorectal cancer cell lines. This analysis was based on a combination of denaturing HPLC mutation screening of all exons of the p53 gene, sequencing the cDNA, and assessing the function of the p53 protein by assaying the induced expression of phosphorylated p53 and p21 after exposing cells to gamma-rays. In a few cases where there was no production of p53 message nor evidence of functional p53 protein, all of the p53 exons were sequenced directly. Thirteen of the 56 cell lines had functional p53, 21 lines had missense mutations (one of which made no detectable protein), 4 lines produced no p53 transcripts, and the remaining 18 lines carried truncating TP53 mutations. Thus, our results showed a relatively high frequency of TP53 mutations (76.8%) in our cell lines, with almost half of the mutations being truncating mutations. This is a rather higher frequency of such mutations than usually reported. Of the 18 cell lines with truncating mutations, 12 had detectable truncated protein based on Western blot analysis, whereas no protein was detected in the remaining 6 cell lines. Our data provide a valuable source of TP 53 mutations for further studies and raise the question of the extent to which truncating mutations may have dominant negative effects, even when no truncated protein can be detected by standard methods.
SIP security problems in NGM Services (2007)

A variety of wireless interfaces are available to access Internet content in a heterogeneous network composed by technologies with limited QoS abilities. Performance increasing solutions become economic in specific parts of the network architecture, as the network sizes and the clients' numbers increase. SIP is used to locate the called party to check that the capabilities of the calling and called parties are consistent and to establish and control the connection. In this paper, we propose an addition to the SIP header/message compression methodology to improve the network QoS by implementations of SIP protocol quality options. We also deal with related SIP security issues regarding practicality and realization possibilities. This paper would like to highlight that security vulnerabilities, open problems may exist using the SIP protocol in usual cases of the practical usage.
Adsorption Kinetics in a Dual-Inlet Channel Flow Cell:  I. Cetyl Pyridinium Chloride on Hydrophilic Silica (2007)

A dual-inlet channel flow cell has been developed for the study of the adsorption kinetics of surfactants to solid−liquid interfaces under hydrodynamic control. This cell, with ellipsometric detection of the adsorbed surfactant, has been used to study the adsorption kinetics of cetyl pyridinium chloride (CPC) to hydrophilic silica in 0.1 M KCl and in pure water. The methodology provides detailed insight into the kinetic parameters and casts light on the adsorption mechanisms. The convection−diffusion behavior in the cell was calculated numerically using the backward implicit finite difference (BIFD) method: the CPC monomer and micelle populations were modeled with constant diffusion coefficients and assumed to equilibrate quickly on the time scale of the experiment. A Frumkin model was used to describe the adsorption behavior at the silica surface: the fitting parameters were determined from the equilibrium adsorption isotherm and kinetically limited desorption measurements. The adsorption kinetics in the cell were then modeled with no free parameters. Adsorption was in the mixed diffusion-kinetic regime under the mass transport conditions of the channel flow cell (adsorption times on the order of tens of seconds). The Frumkin model described well the adsorption of CPC in 0.1 M KCl, but in pure water the fit to the equilibrium adsorption isotherm and the adsorption kinetics was poor. In the presence of 0.1 M KCl, the kinetic parameters suggest a late transition state in the adsorption process. In the absence of salt, both the adsorption and desorption rate constants increase with surface coverage, possibly suggesting a change in mechanism. The experimental methodology can be used to study alternative surfaces and mixed surfactant/polymer systems without modification and can be adapted to study faster kinetics and to incorporate different detection methods.
TreadMarks: shared memory computing on networks of workstations (1996)

Shared memory facilitates the transition from sequential to parallel processing. Since most data structures can be retained, simply adding synchronization achieves correct, efficient programs for many applications. We discuss our experience with parallel computing on networks of workstations using the TreadMarks distributed shared memory system. DSM allows processes to assume a globally shared virtual memory even though they execute on nodes that do not physically share memory. We illustrate a DSM system consisting of N networked workstations, each with its own memory. The DSM software provides the abstraction of a globally shared memory, in which each processor can access any data item without the programmer having to worry about where the data is or how to obtain its value.
Whole-Genome DNA Methylation Profiling of CD14+ Monocytes Reveals Disease Status and Activity Differences in Crohn’s Disease Patients (2020)

Crohn's disease (CD) is a multifactorial incurable chronic disorder. Current medical treatment seeks to induce and maintain a state of remission. During episodes of inflammation, monocytes infiltrate the inflamed mucosa whereupon they differentiate into macrophages with a pro-inflammatory phenotype. Here, we sought to characterize the circulating monocytes by profiling their DNA methylome and relate it to the level of CD activity. We gathered an all-female age-matched cohort of 16 CD patients and 7 non-CD volunteers. CD patients were further subdivided into 8 CD patients with active disease (CD-active) and 8 CD patients in remission (CD-remissive) as determined by the physician global assessment. We identified 15 and 12 differentially methylated genes (DMGs) when comparing CD with non-CD and CD-active with CD-remissive, respectively. Differential methylation was predominantly found in the promoter regions of inflammatory genes. Comparing our observations with gene expression data on classical (CD14<sup>++</sup>CD16<sup>-</sup>), non-classical (CD14<sup>+</sup>CD16<sup>++</sup>) and intermediate (CD14<sup>++</sup>CD16<sup>+</sup>) monocytes indicated that while 7 DMGs were differentially expressed across the 3 subsets, the remaining DMGs could not immediately be associated with differences in known populations. We conclude that CD activity is associated with differences in DNA methylation at the promoter region of inflammation-associated genes.
Ad hoc on-demand multipath distance vector routing (2002)

We present AOMDV, an on-demand multipath distance vector protocol for mobile ad hoc networks. AOMDV is based on a prominent on-demand single path protocol called AODV. AOMDV establishes multiple loop-free and link-disjoint paths. Performance comparison of AOMDV with AODV using ns-2 simulations under varying node speeds shows that AOMDV provides a factor of two improvement in delay and about 20% reduction in routing overhead, while having similar packet delivery fraction.
The Laboratory Rat: Relating Its Age With Human's. (2013)

By late 18(th) or early 19(th) century, albino rats became the most commonly used experimental animals in numerous biomedical researches, as they have been recognized as the preeminent model mammalian system. But, the precise correlation between age of laboratory rats and human is still a subject of debate. A number of studies have tried to detect these correlations in various ways, But, have not successfully provided any proper association. Thus, the current review attempts to compare rat and human age at different phases of their life. The overall findings indicate that rats grow rapidly during their childhood and become sexually mature at about the sixth week, but attain social maturity 5-6 months later. In adulthood, every day of the animal is approximately equivalent to 34.8 human days (i.e., one rat month is comparable to three human years). Numerous researchers performed experimental investigations in albino rats and estimated, in general, while considering their entire life span, that a human month resembles every-day life of a laboratory rat. These differences signify the variations in their anatomy, physiology and developmental processes, which must be taken into consideration while analyzing the results or selecting the dose of any research in rats when age is a crucial factor.
HRQoL assessment by SRS-30 for Chinese patients with surgery for Adolescent Idiopathic Scoliosis (AIS) (2015)

SRS-30 as a health-related quality of life (HRQoL) questionnaire was established since 2003. Literatures from Asian countries on SRS-30 mainly derived from local adaptation and related validation studies. Reports on its use for measuring surgical outcomes were sparse, particularly in the Chinese community. We carried out a retrospective cohort study using SRS-30 to evaluate HRQoL for Chinese AIS adolescents before and after surgery.
Support Screening Studies on the Hydrogenation of Levulinic Acid to γ-Valerolactone in Water Using Ru Catalysts (2016)

γ-Valerolactone (GVL) has been identified as a sustainable platform chemical for the production of carbon-based chemicals. Here we report a screening study on the hydrogenation of levulinic acid (LA) to GVL in water using a wide range of ruthenium supported catalysts in a batch set-up (1 wt. % Ru, 90 °C, 45 bar of H2, 2 wt. % catalyst on LA). Eight monometallic catalysts were tested on carbon based(C, carbon nanotubes (CNT)) and inorganic supports (Al2O3, SiO2, TiO2, ZrO2, Nb2O5 and Beta-12.5). The best result was found for Ru/Beta-12.5 with almost quantitative LA conversion (94%) and 66% of GVL yield after 2 h reaction. The remaining product was 4-hydroxypentanoic acid (4-HPA). Catalytic activity for a bimetallic RuPd/TiO2 catalyst was by far lower than for the monometallic Ru catalyst (9% conversion after 2 h). The effects of relevant catalyst properties (average Ru nanoparticle size, Brunauer-Emmett-Teller (BET) surface area, micropore area and total acidity) on catalyst activity were assessed.
Cincinnati Big Area Additive Manufacturing (BAAM) (2015)

Oak Ridge National Laboratory (ORNL) worked with Cincinnati Incorporated (CI) to demonstrate Big Area Additive Manufacturing which increases the speed of the additive manufacturing (AM) process by over 1000X, increases the size of parts by over 10X and shows a cost reduction of over 100X. ORNL worked with CI to transition the Big Area Additive Manufacturing (BAAM) technology from a proof-of-principle (TRL 2-3) demonstration to a prototype product stage (TRL 7-8).
Lewisx- and sialylated Lewisx-related antigen expression in human malignant and nonmalignant colonic tissues. (1986)

Biochemical studies have revealed that some normal cells express the LeX trisaccharide Gal beta 1----4(Fuc alpha 1----3)GlcNAc either on short-chain fucolipids or as a single immunodeterminant on glycolipid oligosaccharide side chains. Cancer cells, including those from colonic adenocarcinomas, express this antigen on longer type 2 blood group side chains as difucosylated or trifucosylated fucolipids. Moreover, sialylated forms of difucosylated LeX also accumulate in colon cancer but not in normal colonic mucosa. In the present study, six monoclonal antibodies which selectively recognize the various LeX-related antigens were used for immunohistochemical examination of these antigens in serial sections of human colonic tissue. All of these antigens were oncodevelopmental in human colon. Monoclonal antibodies anti-SSEA-1 and AH8-183, directed against short-chain, monofucosylated LeX, were unable to discriminate well between normal and malignant colonic tissue. However, the other four antibodies were much better at distinguishing cancer from normal tissue. FH6 was the most specific in that no normal tissues bound this antibody. However, FH6 failed to stain poorly differentiated cancers and some colloid-type carcinomas. FH4, which was also highly specific, stained almost all cancers, regardless of the degree of differentiation. FH4 primarily stained cancer cell cytoplasm, whereas the sialylated antigen defined by FH6 predominantly stained cell membranes. Differences were noted between the expression of LeX-related antigens in autopsied normal mucosa compared to mucosa of benign colonic diseases. Monoclonal antibodies recognizing long-chain polyfucosylated and sialylated LeX-related antigens appear to be useful tools for detection of colon cancer.
Acetylation of aromatic ethers using acetic anhydride over solid acid catalysts in a solvent-free system. Scope of the reaction for substituted ethers (2003)

The acetylation of aryl ethers using acetic anhydride in the presence of zeolites under modest conditions in a solvent-free system gave the corresponding para-acetylated products in high yields. The zeolite can be recovered, regenerated and reused to give almost the same yield as that given when fresh zeolite is used.
SU‐GG‐I‐100: A Mesh‐Based Anatomical Deformation Method for Creating Size‐Adjustable Whole‐Body Patient Models (2008)

Purpose: Whole‐body patient models are needed for the assessment of organ doses in various CT imaging and external‐beam radiation treatment procedures. The Boundary REPresentation (BPRE) type of geometry offers greater control over the anatomical shapes and tissue/organ surfaces could be flexibly deformed. Currently tedious and time‐consuming manual adjustment is necessary. This paper discusses an automatic modeling method recently developed to create two adjustable adult male and female mesh models with dynamically deformable organs. Method and Materials: The algorithm for the development of the deformable RPI Adult Male/Female phantoms was implemented by MATLAB® 7.4. The anatomical mesh models were based the Anatomium™ 3D models whose organ geometries were morphed to agree within 0.5% with the ICRP reference male and female organ volume/mass data. These mesh morphing algorithms were used to automatically pre‐modify the dataset to have unique mesh information in each of organ boundaries and deform the whole meshes based on the ICRP volume/mass reference without unwanted surface overlapping through the special mesh overlap avoiding process. After the deformations, the RPI Adult Male/Female mesh models were transformed to the solid geometries through the voxelization process with 3.2 mm and 3.0 mm, respectively. Results: These phantoms have been used by transforming the solid geometries into the voxel domain that is compatible with well‐validated Monte Carlo radiation transport simulations such as MCNP, EGSnrc and GEANT4codes. Through these mesh deformation algorithms, complicated bone (cavity, spongiosa, and cortical bones) and muscle structures have been described in the RPI Adult Male/Female mesh models. Conclusion: This study has demonstrated the feasibility to create deformable RPI Adult Male/Female phantoms. These phantoms will be applied to various applications of including person specific adjustments depended on age, weight, and height changes.
Molecular genetics of herpes simplex virus. V. Characterization of a mutant defective in ability to form plaques at low temperatures and in a viral fraction which prevents accumulation of coreless capsids at nuclear pores late in infection (1981)

In herpes simplex virus-infected cells, coreless capsids accumulate at the nuclear pores soon after infection, but subsequently disappear, suggesting that, as in adenovirus-infected cells (S. Dales and Y. Chardonnet, Virology 56:465-483, 1973), the release of viral DNA from nucleocapsids takes place at the nuclear pores. A nonlethal mutant, HSV-1(50B), produced by mutagenesis of HSV DNA fragments and selected for delayed production of plaques at 31 degrees C, accumulated coreless capsids at the nuclear pores late in infection in contrast to wild-type viruses. Recombinants selected for ability to produce plaques at 31 degrees C by marker rescue with digests of herpes simplex virus 2 DNA and selected clone fragments of HSV-1 DNA no longer accumulated empty capsids at nuclear pores late in infection. These results suggest that herpes simplex viruses encode a function which prevents accumulation of coreless capsids at nuclear pores, presumably by preventing uptake, unenvelopment, and DNA release from progeny virus, and indicate that the cold sensitivity of plaque formation and accumulation of coreless capsids might be related or comap in the S component of the genome.
A multisystems on screen display for TV MCU (1989)

A novel on-screen display system for TV incorporated into an application-specific MCU (microprocessor control unit) is described. It uses the PLL (phase-locked loop) technique and is compatible with all currently known scanning standards which are detected automatically. The circuit is developed so that the characters are stable regardless of system change. Special techniques are used to minimize the horizontal jitter of the display.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
A Survey on Mix Networks and Their Secure Applications (2006)

Anonymity is a subdiscipline of information hiding, required in a number of applications, such as in electronic voting. For network communications, anonymity can be provided by a mix network (mixnet). A mixnet is a multistage system that uses cryptography and permutations to provide anonymity. The basic idea of a mixnet has evolved into a number of different classes. In addition to presenting the existing mixnet classifications, this paper classifies mixnets based on the verification mechanisms employed for robustness. The construction of mixnets is presented under a common framework to provide insight into both the design and weaknesses of existing solutions. Basic forms of attack on mixnets and the corresponding robustness solutions are reviewed. Comparison with other solutions for anonymity and suggestions for interesting future research in mix networks are also provided
Theoretical and numerical studies of constitutive relations for frictional granular flow (1991)

The purpose of this report is to propose a suitable constitutive relationship for the three dimensional frictional flow of a cohesionless granular material and to incorporate at least a qualitatively similar constitutive relationship in the computer program TEACH. TEACH is a hydrodynamic code developed by Dr. A.D. Gosman at Imperial College, London, for the simulation of incompressible two dimensional steady duct flows. Simulations performed for this report assumed that the material was flowing under two dimensional plane strain conditions. The numerical algorithm implemented by TEACH is based upon the control volume finite difference principles developed by Spalding and Patankar (Patankar, 1980). TEACH's program structure facilitates the implementation of a non-Newtonian constitutive relationship of the type proposed below. 32 refs., 38 figs., 2 tabs.