gebhart/patrepeval huggingface dataset:
Effect Of Aspirin On The Production Of PGI2 By Various Blood Vessels And Mda By Platelets (1981)

This study was desinged to determine whether the differential inhibition of prostacyclin(PGI2) production by vessel wall and malondialdehyde(MDA) production by platelet might be possible by oral administration of aspirin(ASA). Rabbits weghing 2-3kg were used. MDA production by platelet was measured by the Stuart’s method with minor modification. The PGI2 production by vessel wall was assessed by the Moncada’s method with minor modification. The PGI2 production by caval vein, pulmonary artery, pulmonary vein,femoral artery, femoral vein and coronary artery was 148±55%, 136±56%, 153±55%, 134±56%, 123±64%, 103±55% to that of aorta, respectively. The PGI2 production by these vessels was inhibited to 20-40% to their initial level 6h after the single oral administration of 0.3g ASA, and restored to the initial level by 24h, while the MDA production was inhibited more conspicuously and remained at less than 50% of the initial level even 48h. The effect of daily oral administration of ASA on production of PGI2 by aorta and MDA by platelet was investigated. PGI2 production was suppressed to about 10% of the initial level 24h after the last dose of 3 to 7 daily administration of 0,3g of ASA. This indicates that the daily ASA administration results in the cummulative inhibition of PGI2 production. On the other hand, when administered every other day, the same amount of ASA exerted significantly less inhibition of PGI2 production, being at about 50% of initial level 24h after the last dose. MDA production was nearly completely inhibited over the observation periods. These results suggests that the differential inhibition of vascular PGI2 production and platelet aggregation may be possible by the administration of ASA at an appropriate amount and proper interval.
Transient loss of consciousness as reason for admission to primary health care emergency room (2003)

Loss of consciousness is a fairly frequent problem for the primary health care emergency room. A history of alcohol abuse is commonly associated with seizures.
Abstract PR03: Linking AP/MS-driven protein-protein interaction networks and combination CRISPR/sgRNA screens defines new Kras effectors and target candidates for non-small cell lung cancer (2017)

Abstract The Kras pathway is a central driver in prevalent and deadly cancers including pancreas, colon and lung. Despite decades of work studying the Raf and PI3 kinase pathways downstream of Kras, therapies targeted to these pathways have shown varied responses in tumors To better understand whether important Kras dependences have been overlooked, we used tandem affinity purification of Kras, Hras, and Nras interactors and a set of baits representing ~50 interacting pathway regulators, and have compared these interactions in Kras transformed A549 NSCLC lines versus an isogenic shRNA Kras knockdown line, to identify key protein-protein interactions (PPIs) linked to Kras effector activity. These interactions were curated and compared to public PPI, genetic susceptibility, and other multiomics data to assemble a physical PPI map annotated with important functional determinants. This functional map was used to construct a library of 114 selected sgRNAs (10 guides per gene) and screened in a 1140 x 1140 dual sgRNA vector system to look for quantitative changes in single and dual genetic dependencies in A549 cell growth. We discovered a considerable number of new KRAS GTP-specific effectors important in NSCLC cancer, many with strong mutations patterns supported by TCGA data and validated by in vitro biochemical assay. We will present these data and additional validation studies on two pathways including the Radil-Rap1-Kif14 pathway for cell migration and an extensive interaction of the Kras pathway with Ral and Rap GTPase family guanine nucleotide exchange factors. These new effectors underscore limitations in our functional understanding of transformation in Kras-driven tumors and suggest specific new targets for these critical tumors. Citation Format: Marcus R. Kelly, Han Kyuho, Edwin E. Jeng, David Morgans, Kaja Kostyrko, David Simpson, Dana Gwinn, Alejandro Sweet-Cordero, Michael C. Bassik, Peter K. Jackson. Linking AP/MS-driven protein-protein interaction networks and combination CRISPR/sgRNA screens defines new Kras effectors and target candidates for non-small cell lung cancer [abstract]. In: Proceedings of the AACR Precision Medicine Series: Opportunities and Challenges of Exploiting Synthetic Lethality in Cancer; Jan 4-7, 2017; San Diego, CA. Philadelphia (PA): AACR; Mol Cancer Ther 2017;16(10 Suppl):Abstract nr PR03.
Residual Coulomb Interaction Fluctuations in Chaotic Systems: The Boundary, Random Plane Waves, and Semiclassical Theory (2008)

New fluctuation properties arise in problems where both spatial integration and energy summation are necessary ingredients. The quintessential example is given by the short-range approximation to the first order ground state contribution of the residual Coulomb interaction. The dominant features come from the region near the boundary where there is an interplay between Friedel oscillations and fluctuations in the eigenstates. Quite naturally, the fluctuation scale is significantly enhanced for Neumann boundary conditions as compared to Dirichlet. Elements missing from random plane wave modeling of chaotic eigenstates lead surprisingly to significant errors, which can be corrected within a purely semiclassical approach.
ChemInform Abstract: TWIN ANNULATION OF NAPHTHALENE VIA A 1,5‐NAPHTHODIYNE SYNTHON. NEW SYNTHESES OF CHRYSENE AND DIBENZO(B,K)CHRYSENE (1983)

Abstract Aus 2,6‐Dibrom‐l ,5‐naphthalindiol (Ia) erhält man über das‐ Bis‐tosylat (Ib) ein Bis‐arin (II), das mit Furan (III) zu einem Addukt (IV) führt.
P24: Impact of FiO2 on blood oxygenation in Pediatric MLung (2022)

Purpose: Patient-healthcare provider access, increasingly strained in recent years, was further limited dramatically by COVID. Reduced physical access to care necessarily sparked near total reliance on telehealth/telemedicine modalities, which undoubtedly will continue to grow in the future. Platforms such as Zoom, Teams and Meet, while effective in facilitating video interactions are limited as to capabilities for physical examination and dynamic assessment of patients. We developed and validated a methodology, a mobile motion capturesystem, employing visual markers, smartphone-based video capture and computational analytics, for motion capture and analysis via telehealth. Here we examined the translational clinical utility of this approach applied to two physical diagnostic testing maneuvers: 1. Finger abduction/adduction, and 2. Lateral flex. Methods: Bright colored markers were placed on human volunteers wearing dark attire. Finger abduction/adduction: 3 markers (2x2 mm.) were placed – two on the distal inter-phalangeal joint of the second and third digits, and one in between the metacarpal phalangeal joints of the second and third digits. Lateral bending: 2 markers (10x10 mm.) were placed – one at the inferior aspect of the cervical spine, and a second at thoracic/superior lumbar spine. Subjects were instructed and performed diagnostic maneuvers – either as full excursion or as limited excursion - as facsimiles of disease with reduced range-of motion, tele-videos were recorded, analyzed and range of motion reported (degrees of excursion). Results: For all maneuvers performed, smartphone videos of marker-tagged patients allowed tracking and capture of regional body motion and analysis of the extent of motion quantitatively. Range of motion for finger abduction/adduction was measured as 34.3o for full excursion vs. 23.3o for the disease facsimile. For lateral flex, full excursion was 32o vs. 18o for the disease facsimile. All measurements are consistent with values of in-person testing. Conclusions: Our results demonstrate the translational clinical utility of video-based motion capture as a useful tool to enhance physical diagnosis for telemedicine. Visual marker tagging of patients combined with smartphone video capture and analysis is an effective method for adding outpatient remote physical examination capabilities to telemedicine visits to enhance quantitative follow-up.
Image Mining Based on Deep Belief Neural Network and Feature Matching Approach Using Manhattan Distance (2021)

Over the past few decades multimedia content, particularly digital images, has increased at a rapid pace, with several complex images being uploaded to various social websites such as Instagram, Facebook and Twitter. Therefore, it is difficult to search and retrieve the relevant image in seconds. Search engines retrieve images based on traditional textbased methods that depend on metadata and captions. In the last few years, a wide range of research has focused on content-based image retrieval (CBIR) based on image mining approaches. This is a challenging research area due to the ever-increasing multimedia database and other image libraries. In order to offer an effective search and retrieval, a novel CBIR system is proposed using the image mining-based deep belief neural network (IMDBN) technique. The proposed method is designed to enhance retrieval accuracy while diminishing the semantic gap between human visual understanding and image feature representation. To achieve this objective, the proposed system carries several steps like preprocessing, feature extraction, classification, and feature matching. Initially, the input database images are fed into the proposed image mining-based CBIR system, whereas colour-shape-texture (CST) feature extraction technique is applied to extract relevant feature set. The extracted features are fused and stored in the feature vector and are subjected to the proposed IMDBN classification step to retrieve similar images in one label. Whenever a new query content is created, the most relevant images are retrieved. This, in turn, achieves 94% accuracy, which is higher than in existing approaches.
Designing Web-based adaptive support for debate with dialogue modelling (2002)

We present an approach to computer-based education that takes advantage of dialogue modelling. Dialogue modelling is examined with a view to using it to provide the models needed to develop Web-based adaptive support for online argumentative debate, specifically debate about design evaluation issues for multimedia students. Our work is motivated by the fact that certain domains are very difficult to produce models that can form the basis for systems design. Dialogue analysis and dialogue modelling techniques are then briefly explored to see if they can be used to meet the implementation challenge of building to a Web-based pedagogical agent in the real-world situation of supporting undergraduate multimedia studies.
Head2Head++: Deep Facial Attributes Re-Targeting (2021)

Facial video re-targeting is a challenging problem aiming to modify the facial attributes of a target subject in a seamless manner by a driving monocular sequence. We leverage the 3D geometry of faces and Generative Adversarial Networks (GANs) to design a novel deep learning architecture for the task of facial and head reenactment. Our method is different to purely 3D model-based approaches, or recent image-based methods that use Deep Convolutional Neural Networks (DCNNs) to generate individual frames. We manage to capture the complex non-rigid facial motion from the driving monocular performances and synthesise temporally consistent videos, with the aid of a sequential Generator and an ad-hoc Dynamics Discriminator network. We conduct a comprehensive set of quantitative and qualitative tests and demonstrate experimentally that our proposed method can successfully transfer facial expressions, head pose and eye gaze from a source video to a target subject, in a photo-realistic and faithful fashion, better than other state-of-the-art methods. Most importantly, our system performs end-to-end reenactment in nearly real-time speed (18 fps).
Two-Wave Shock Structures in the Ferroelectric Ceramics Barium Titanate and Lead Zirconate Titanate (1962)

Two ferroelectric ceramics, Pb (Zr0.52, Ti0.48)O3 with 1 wt % Nb2O5 and pure BaTiO3, were studied under shock wave loading. Plane shock waves having pressures ranging from 2 to 175 kbar were produced by high-explosive driving systems. Measurements were made with a streak camera and shock-detecting ferroelectric wafers. Both ceramic materials showed evidence of a two-wave structure over a wide range of shock pressures. Results indicate that these two-wave structures are characteristic of the elastic properties of the materials and are not due to phase transitions from ferroelectric to paraelectric. Pressure-volume Hugoniot curves are presented for both materials. Electrical charge released to an external load by Pb (Zr0.52, Ti0.48)O3 with 1 wt % Nb2O5 was measured as a function of the pressure of a shock which was moving parallel to the axis of polarization. The primary mechanism in this reduction of polarization by shocks was found to be, not a phase transition or domain switching, but merely a reduction of the dipole moment by axial compression.
LES based evaluation of multi-component fuel evaporation effects at aero-engine conditions (2016)

A new multi-component evaporation model was developed as a part of a study to accurately simulate realistic alternative aviation fuels that may have widely varying fuel physical properties. While the new model is based on the fuel Distillation Curve (DC) it is characterized by notable differences from conventional DC models in the literature. These differences as well as similarities of the current model with the conventional models are described to highlight the strengths and limitations of each of these models. Partial validation of the new model is demonstrated by performing single droplet evaporation tests similar to those available in the literature and the results were compared with the conventional DC model. The impact of pressure on evaporation was demonstrated by simulating single droplet evaporation at different pressures and highlighting the two competing mechanisms, namely heat of vaporization effect and multi-component fuel volatility effects. The newly developed DC model was applied to simulate swirl-stabilized combustor experiments where two alternative jet fuels were employed to study the impact of fuel properties on lean-blow-out. Simulations of stable operating conditions were performed using a low-Mach number LES using flamelet-progress variable approach. These simulations demonstrated that the current models can qualitatively capture the fuel sensitivity on flame stabilization. Further refinement of the LES models (in terms of boundary conditions and computational domain) are required to obtain quantitatively accurate predictions of the flow-fields. This will be the subject of future work.
High electrical conductivity of composite ceramics consisting of insulating oxide and ordered perovskite conducting oxide (2017)

We have prepared and characterized composite ceramics of CaCu3Ru4O12 and CuO, and have found that it possesses an excellent conductivity of 1000 S cm−1 from room temperature to 700 °C in air, up to 30 vol.% of CuO addition. The measured resistivity and thermopower are well described with a percolation theory, from which we find that the good electrical properties of CaCu3Ru4O12 remain up for to 75 vol.% CuO addition. CuO does not only reduce materials cost, but also works as a sintering additive to improve the densification in sintering. It also increases the sticking coefficient to substrate materials, as is verified in a thick film of this composite ceramics prepared by a screen-printing process. We propose that CuO-mixed CaCu3Ru4O12 is a highly conductive, chemically stable, and low-cost material to be used as a conducting paste.
Recovery of ventricular pressure after long-duration fibrillation/asystole (2002)

When ventricular fibrillation occurs out-of-hospital, fewer than 3% of patients survive to hospital discharge. Following long fibrillation durations associated with out-of-hospital fibrillation, asystole or electromechanical dissociation (EMD) frequently follows the defibrillating shock. When this happens, recovery of spontaneous circulation rarely occurs. Therefore, this study tested the hypothesis that ventricular recovery from asystole or EMD is possible if the heart is subsequently perfused at normal pressures with O/sub 2/ saturated solution. Isolated rabbit hearts (n=5) were subjected to 9 minutes ischemic fibrillation followed by a defibrillating shock. All hearts converted to asystole or EMD. At 23 seconds following the shock, the hearts were reperfused with oxygenated solution. Ventricular pressure recovered 57.2/spl plusmn/11.9% of control at 36.0/spl plusmn/1.9 seconds and 76.2/spl plusmn/11.8% at 5 minutes. These results suggest that rapid pressure recovery is possible after 9 minutes of ischemic fibrillation where the defibrillating shock leads to asystole or EMD, and that recovery can occur in the absence of epinephrine or CPR prior to the shock.
Motion compensated frame rate conversion using normarized motion estimation (2006)

Frame rate conversion is effective to solve degradation of motion picture quality at liquid crystal display. It is also useful for low picture rate video signal such as movie. In case of conversion, basic motion compensation causes gap at covered area and uncovered area. To avoid the gap, we propose the motion compensation centered at the position of target. Fully motion compensated interpolation is possible in this method. To realize this, error normalizing by block activity is used for motion estimation. We also propose the adaptive interpolation by using four frames. Finally, we compare the original picture with the interpolated picture converted from decimated picture. The proposed conversion method gives 5 dB better at the maximum PSNR than the conventional method.
Phase 1 Integrated Systems Test and Characterization Report for the 5-Megawatt Dynamometer and Controllable Grid Interface (2018)

This report details the commissioning of the 5-MW dynamometer and Controllable Grid Interface (CGI) at the National Wind Technology Center (NWTC) at the National Renewable Energy Laboratory (NREL). The purpose of these characterization tests was to verify the dynamometers performance over the widest possible range of operating conditions, verify interconnection with and fault generation capability of the CGI, gain insight into system-level behavior, and establish confidence in measurement data.
Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on the Evaluation and Treatment of Patients with Thoracolumbar Spine Trauma: Executive Summary (2018)

The available evidence for the evaluation and treatment of patients with thoracolumbar spine injuries demonstrates considerable heterogeneity and highly variable degrees of quality. However, the workgroup was able to formulate a number of key recommendations to guide clinical practice. Further research is needed to counter the relative paucity of evidence that specifically pertains to patients with only thoracolumbar spine injuries. The full version of the guideline can be reviewed at: https://www.cns.org/guideline-chapters/congress-neurological-surgeons-systematic-review-evidence-based-guidelines/chapter_1.
Bewertung von Biegeschwingungen (2001)

Kurzfassung Jedem Maschinenbauingenieur ist die biegekritische Drehzahl ein Begriff, der neben anderen mechanisch fundierten Grundlagen, wie dem Hook'schen Gesetz, der Hertz'schen Pressung oder den Euler'schen Knickfällen, zum Handwerkszeug der gebräuchlichen Auslegungsbeziehungen für die Maschinenelemente gehört. Gewöhnlich liefert die Behandlung der biegekritischen Drehzahl im Studium den ersten anschaulichen Bezug zu den Wirkungen dynamischer Systemeigenschaften. Die Theorie von Eigenfrequenz, erzwungener Schwingung und Resonanz findet ihre Anwendung bei der „Nachrechnung“ drehender elastischer Wellen, beispielsweise in Zahnradgetrieben oder anderer elastischer Rotoren in Antriebssystemen.
Indications for resection and radiosurgery for brain metastases (2005)

This is a review of the literature from May 2004 to June 2005 with special attention on publications related to effect on quality of life with different procedures and therapies.
Les mares du parc urbain de montaigu : Microflore, microfaune et faune d'invertébrés (2004)

Before differentiated cell transplantation, transmyocardial revascularization and vascular endothelial growth factor administration caused an angiogenesis effect to enhance neovascularization. It may be superior in attenuating the progression of cardiac dysfunction in the rat model compared with the myocardial infarct rat transplanted cell alone.
Capacity of multi-antenna array systems in indoor wireless environment (2002)

Previous studies have shown that a wireless system using n transmitting and n receiving antennas can achieve a capacity n times higher than a single-antenna system in an independent Rayleigh fading environment. We explore the capacities of multiple-element antenna arrays (MEAs) in a more realistic propagation environment simulated via the WiSE ray-tracing tool. We impose an average power constraint and collect statistics of the capacity with optimal power allocation, C/sub wf/, and the mutual information with an equal power allocation, I/sub eq/. In addition, we present expressions for the asymptotic growth rates C/sub wf//n and I/sub eq//n as n/spl rarr//spl infin/ for two cases: (a) independent fadings and (b) correlated fadings at different antennas. We find that C/sub wf//n and I/sub eq//n converge to constants C/sub wf/* and I/sub eq/*, respectively in case (a), and to C/sub wf//sup 0/and I/sub eq//sup 0/ in case (b). We observe that C/sub wf//sup 0/ and I/sub eq//sup 0/ predict very closely the slopes observed for simulated channels, even for moderate n (i.e., 16).
Retrograde coronary sinus versus aortic root perfusion with cold cardioplegia: randomized study of levels of cardiac enzymes in 40 patients. (1986)

Myocardial injury was assessed with the use of enzyme indexes in 40 patients randomly assigned to one of two groups undergoing coronary artery bypass surgery. Twenty patients received cold cardioplegia delivered by retrograde coronary sinus perfusion and 20 received cardioplegic solution by anterograde aortic root perfusion. Creatine kinase isoenzyme MB and lactate dehydrogenese isoenzyme 1 and isoenzyme 2 assays were carried out on blood samples obtained from the coronary sinus before aortic cross-clamping and 0, 5, and 30 min after aortic unclamping. Levels of these enzymes were also obtained from venous blood samples before aortic cross-clamping and 3, 8, 14, and 20 hr after aortic unclamping and 2, 3, 4, and 5 days after surgery. Preoperative and postoperative hemodynamic measurements (Swan-Ganz catheter) and radionuclide wall motion studies were also obtained for comparison. There was no overall significant difference between the two groups postoperatively in terms of enzyme indexes, hemodynamic measurements, or results of wall motion studies. We conclude that retrograde coronary sinus perfusion is an alternative to aortic root perfusion in delivering cold cardioplegia. More studies are required to determine which subgroup of patients with coronary artery disease may benefit from retrograde coronary perfusion.
AlMe3-Promoted Oxidative Cyclization of η2-Alkene and η2-Ketone on Nickel(0). Observation of Intermediate in Methyl Transfer Process (2005)

AlMe3 can promote the oxidative cyclization of eta2-alkene and eta2-ketone on nickel(0) to give an intriguing nickel-aluminum dinuclear complex having a bridging methyl group, which might be an intermediate for the nickel-catalyzed cycloisomerization of o-allylacetophenone or o-allylbenzophenone.