gebhart/patrepeval huggingface dataset:
Fixed-Wing Attitude Estimation Using Computer Vision Based Horizon Detection (2007)

The last decade has seen a dramatic expansion in the deployment of Unmanned Airborne Vehicles (UAVs) as witnessed by deployments to Bosnia, Afghanistan and Iraq. Many low-cost UAVs operate without redundant attitude sensors and are therefore highly vulnerable to the failure of such sensors. It is common for low-cost UAVs to carry a vision sensor as its primary payload. Given that a human pilot is trained to control an aircraft with respect to a visual horizon under Visual Meteorological Conditions (VMC), it is logical to suggest that a similar capability be developed for a UAV in the event of the failure of the primary attitude system. In addition, it potentially gives the capability to estimate the attitude of a gimballed camera, without specifically equipping the gimballed platform with an angular sensor. In this paper, we develop a method for estimating the flight critical parameters of pitch angle, roll angle and the three body rates using horizon detection and optical flow. We achieve this through the use of an image processing front-end to detect candidate horizon lines through the use of morphological image processing and the Hough transform. The optical flow of the image for each candidate line is calculated, and using these measurements, we are able to estimate the body rates of the aircraft. Using an Extended Kalman Filter (EFK), the candidate horizon lines are propagated and tracked through successive image frames, with statistically unlikely horizon candidates eliminated. Results are shown for a number of different datasets taken with cameras ranging from low-cost webcams to high-quality machine vision cameras are presented. Preliminary results show that although the front-end is adequate in many different scenarios, utilising temporal information results in a more robust performance of the detection algorithm which is well suited for use in attitude estimation.
Kinetics of Alkylation Reactions of Pyrrolizidine Alkaloid Derivatives (1981)

Comparison is made of the alkylating activities of a series of semi-synthetic pyrrole esters and pyrrole derivat~ves of pyrrolizidine alkaloids under pseudo-first-order reaction conditions.Examination of the rate data indicates two reaction patterns; those compounds whose rate data fit a simple first-order rate expression and a second group of compounds whose rate data fit a biexponential expression.Pyrrolizidine alkaloids are wdely distributed throughout the world in a variety of plant species.Concern has arisen over involvement of the alkaloids in livestock poisoning and possible contamina-;ion of human food Retronecine (I) forms the pyrroliridine nucleus for many of these alkaloids when esterlfied with various neclc acids.Toxicity of the pyrroliiidine alkaloids may be exerted through the action of pyrrole derivatives which should be highly active alkylat~on agents.Mattocks has proposed a scheme for enzymatic conversion of the alkaloids to pyrrole analogs in the liver and t h e n subsequent distribution and fate.3Robertson, et 2.1.. have presented evidence that nucleophilic substitution by cysteine and glutathione occurs preferentially at C-7 of dehydroretronecine (11). 4In this study, the alkylating activities of a series of semi-synthetic pyrrole esters (111-XI11 and pyrrole derivatives of pyrroliridine alkaloids (11,XIII-XV) are compared using 4-e-nitrobenzylpyridine as a nucleophile in aqueous acetone at 30' under acid catalyzed pseudo-first-order reaction
Purification and characterization of an endo-exonuclease from Saccharomyces cerevisiae that is influenced by the RAD52 gene. (1987)

An endo-exonuclease has been purified from logarithmically growing cells of the yeast Saccharomyces cerevisiae. Identification and purification of this nuclease was facilitated by its being precipitable with an antibody raised against a previously described Neurospora crassa endo-exonuclease (Resnick, M. A., Chow, T. Y.-K. Nitiss, J., and Game, J. C. (1984) Cold Spring Harbor Symp. Quant. Biol. 49, 639-649 and T. Y.-K. Chow and M. A. Resnick (1988) Mol. Gen. Genet., in press). The enzyme which was purified to near homogeneity was composed of a molecular weight 72,000 monomer. The single-strand nuclease activity is endonucleolytic and nonprocessive, whereas the double-strand DNase activity is exonucleolytic and weakly processive. Both nuclease activities have a pH optimum of 7.5, require Mg2+ or Mn2+ but not Zn2+ or Ca2+, are not inhibited by ATP, and exhibit the same kinetics of heat inactivation. Although this protein is not the product of the RAD52 gene, the greatly reduced amounts in rad52 mutants implicate the enzyme in repair and recombination processes in both mitotic and meiotic cells.
Sodium Gradients, ATP, and Intracellular pH Transients in a New Brainstem-Sparing Model of Reversible Complete Ischemia of Dog Cerebrum (1990)

Log in or Register Subscribe to journalSubscribe Get new issue alertsGet alerts Enter your Email address: Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining your privacy and will not share your personal information without your express consent. For more information, please refer to our Privacy Policy. Subscribe to eTOC Secondary Logo Journal Logo All Articles Images Videos Podcasts Blogs Advanced Search Toggle navigation Subscribe Register Login Articles & Issues Current IssuePrevious IssuesPublished Ahead-of-Print Collections SNACC Clinical Guidelines and Consensus StatementsSNACC Abstracts For Authors Submit a ManuscriptInformation for AuthorsLanguage Editing ServicesAuthor Permissions Journal Info About the JournalEditorial BoardAffiliated SocietiesAdvertisingOpen AccessSubscription ServicesReprintsRights and Permissions All Articles Images Videos Podcasts Blogs Advanced Search
Purple: A Modular System for Developing and Deploying Behavioral Intervention Technologies (2014)

The creation, deployment, and evaluation of Web-based and mobile-based applications for health, mental health, and wellness within research settings has tended to be siloed, with each research group developing their own systems and features. This has led to technological features and products that are not sharable across research teams, thereby limiting collaboration, reducing the speed of dissemination, and raising the bar for entry into this area of research. This paper provides an overview of Purple, an extensible, modular, and repurposable system created for the development of Web-based and mobile-based applications for health behavior change. Purple contains features required to construct applications and to manage and evaluate research trials using these applications. Core functionality of Purple includes elements that support user management, content authorship, content delivery, and data management. We discuss the history and development of the Purple system guided by the rationale of producing a system that allows greater collaboration and understanding across research teams interested in investigating similar questions and using similar methods. Purple provides a useful tool to meet the needs of stakeholders involved in the creation, provision, and usage of eHealth and mHealth applications. Housed in a non-profit, academic institution, Purple also offers the potential to facilitate the diffusion of knowledge across the research community and improve our capacity to deliver useful and usable applications that support the behavior change of end users.
The use of technology in Suicide Prevention (2015)

Suicide is one of the leading causes of death globally, and is notably a significant cause of death amongst young people. A suicide outcome is a complex combination of personal, social, and health factors, and therefore suicide prevention is a challenge, requiring a systems approach incorporating public health strategies, screening at-risk individuals, targeted interventions, and follow-up for suicide survivors and those bereaved by suicide. Engineering practice has been implicated in the hindrance of the adoption of suicide prevention strategies, such as installing safety barriers at the Golden Gate Bridge, however technological developments offer new opportunities in suicide prevention, and the potential to reduce the number of deaths by suicide. We present an overview of current technological developments which are facilitating research in the field of suicide prevention, including multiple modes of screening such as network analysis of mobile-phone collected connectivity data, automatic detection of suicidality from social media content, and crisis detection from acoustic variability in speech patterns. The current field of mhealth apps for suicide prevention is assessed, and an innovative app for an Indigenous population is presented. From this overview, future challenges - technical and ethical - are discussed.
Ultrafiltration conducting membranes and coatings from redispersable, nanoscaled, crystalline SnO2:Sb particles (1999)

Inorganic membranes prepared by the sol-gel method are promising candidates for use as filters in separation processes. Conducting supported membranes and coatings have been produced from redispersable nanoscaled crystalline Sb-doped SnO 2 powders with Sb contents up to 10 mol%. The crystalline particles (ca. 4 nm) are fully redispersable in aqueous solution at pH≥8 with a solid content up to 37 vol.% and are monosized. After thermal treatment at different temperatures and times, the pore size diameter of such a powder can be adjusted from 4-20 nm with a very narrow pore size distribution (ca. ±1 nm) and a total porosity of 63%, practically independent of the sintering parameters. Uniaxial compacted substrates (unsupported membranes) present similar characteristics but with a larger pore size distribution (±5 nm) and 80% total porosity. Their electrical resistance decreases with sintering temperature and time to 4 Ω (800 °C, 8 h). Crack free transparent conducting coatings on glasses and ceramics have been obtained by spin-coating using fully dispersed aqueous solutions of the powder with volume content up to 7.8%. After thermal treatment (1 h at 550 °C) single layers 200 nm thick are still porous and exhibit specific electrical resistivity as low as ρ=2.5×10 –2 Ω cm with 90% transmission in the visible range.
Experimental Test Results for a Fiber Bragg Grating-Based Flow Sensor (2010)

A fiber optic-based mass flow sensor has been developed that uses fiber Bragg gratings to deduce flow velocity. Flow velocity, local temperature, pressure measurements (that all can be extracted using fiber Bragg gratings) and geometric information can be combined to determine mass flow. A range of concepts have been investigated and compared using the same “design of experiment” for each sensor. The most promising concept has been further developed into a prototype. The working prototype successfully demonstrated a thermally insensitive sensor design that has the capability to track flow velocities. The sensor design is incorporated directly with a structural beam element to magnify the strain effect while simultaneously compensating for thermally-induced wavelength shifts in the sensor response. Further testing has been performed using three flexible beams at different angular positions showing that flow angles can be measured similar to the approach used for 3-hole pneumatic probes. As a final test, the sensor has been tested in a shock tube demonstrating superior performance compared to steady pneumatic measurements which rely on tubing to reach the measurement location.
Resistivity of a Simple Metal from Room Temperature to106K (1988)

The resistivity of nearly solid-density Al was measured as a function of temperature over 4 orders of magnitudfe above ambient by observing the self-reflection of an intense, 0.5 psec, 308-nm light pulse incident on a planar Al target. As an increasing function of electron temperature, the resistivity is observed initially to increase, reach a maximum which is relatively constant over an extended temperature range, and then decrease at the highest temperatures. The broad maximum is interpreted as "resistivity saturation," a condition in which the mean free path of the conduction electrons reaches a minimum value as a function of temperature, regardless of the extent of any further disorder in the material.
Light-weight Electrophysiology Hardware and Software Platform for Cloud-Based Neural Recording Experiments (2021)

Abstract Objective Neural activity represents a functional readout of neurons that is increasingly important to monitor in a wide range of experiments. Extracellular recordings have emerged as a powerful technique for measuring neural activity because these methods do not lead to the destruction or degradation of the cells being measured. Current approaches to electrophysiology have a low throughput of experiments due to manual supervision and expensive equipment. This bottleneck limits broader inferences that can be achieved with numerous long-term recorded samples. Approach We developed Piphys, an inexpensive open source neurophysiological recording platform that consists of both hardware and software. It is easily accessed and controlled via a standard web interface through Internet of Things (IoT) protocols. Main Results We used a Raspberry Pi as the primary processing device and Intan bioamplifier. We designed a hardware expansion circuit board and software to enable voltage sampling and user interaction. This standalone system was validated with primary human neurons, showing reliability in collecting real-time neural activity. Significance The hardware modules and cloud software allow for remote control of neural recording experiments as well as horizontal scalability, enabling long-term observations of development, organization, and neural activity at scale.
What Would It Take to Manufacture Perovskite Solar Cells in Space? (2022)

Imagine: Astronauts land on the moon. They verify their arrival with mission control and perform system checks and validations. After the dust settles, they open the airlock of the landing vehicle and venture outside. A side hatch opens, and a flexible substrate slowly unfurls on a boom. A series of printer heads raster, hovering over the substrate and sequentially vapor-depositing the constituent layers of a perovskite solar module. In time, a 1-megawatt array has been manufactured on the moon and can now be connected to supply power to the Artemis Base Camp. This ambitious vision could someday become a reality.
POS-186 AMLODIPINE AS AN ALTERNATIVE ANTIHYPERTENSIVE IN PREGNANCY: A SYSTEMATIC REVIEW (2021)

Hypertension complicates up to 10% of UK pregnancies and is associated with three to five-fold increased risk of pre-eclampsia and adverse perinatal outcome with associated long-term increased risk of cardiovascular disease. The selection of antihypertensive agents in pregnancy is restricted due to concerns over potential adverse effects on the fetus. Amlodipine is used as a first line agent to manage hypertension in many settings outside pregnancy but its safety in human pregnancy is uncertain.Our objective was perform a systematic review of amlodipine use in pregnancy and its association with adverse maternal and perinatal outcome.
1,2,4-Oxadiazoles Identified by Virtual Screening and their Non-Covalent Inhibition of the Human 20S Proteasome (2013)

Although several constitutive proteasome inhibitors have been reported these recent years, potent organic, noncovalent and readily available inhibitors are still poorly documented. Here we used a structure- and ligand-based in silico approach to identify commercially available 1,2,4-oxadiazole derivatives as non-covalent human 20S proteasome inhibitors. Their optimization led to the newly synthesized compound 4h that is a mixed proteasomal inhibitor of the chymotrypsin- like activity (K(i) of 26,1 nM and K'(i) of 7.5 nM) which is in addition selective versus the challenging cathepsin B and calpain proteases. Molecular modelling studies corroborated the mechanism of inhibition and suggest an unusual binding of the inhibitor within the S5 binding pocket (β6 subunit). The cellular effects of our compounds validate their utility as potential pharmacological agents for anti-cancer pre-clinical studies.
Docosahexaenoic Acid Prevents White Matter Damage after Spinal Cord Injury (2010)

We have previously shown that the omega-3 fatty acid docosahexaenoic acid (DHA) significantly improves several histological and behavioral measures after spinal cord injury (SCI). White matter damage plays a key role in neurological outcome following SCI. Therefore, we examined the effects of the acute intravenous (IV) administration of DHA (250 nmol/kg) 30 min after thoracic compression SCI in rats, alone or in combination with a DHA-enriched diet (400 mg/kg/d, administered for 6 weeks post-injury), on white matter pathology. By 1 week post-injury, the acute IV DHA injection led to significantly reduced axonal dysfunction, as indicated by accumulation of β-amyloid precursor protein (-55% compared to vehicle-injected controls) in the dorsal columns. The loss of cytoskeletal proteins following SCI was also significantly reduced. There were 43% and 73% more axons immunoreactive for non-phosphorylated 200-kD neurofilament in the ventral white matter and ventrolateral white matter, respectively, in animals receiving DHA injections than vehicle-injected rats. The acute DHA treatment also led to a significant improvement in microtubule-associated protein-2 immunoreactivity. By 6 weeks, damage to myelin and serotonergic fibers was also reduced. For some of the parameters measured, the combination of DHA injection and DHA-enriched diet led to greater neuroprotection than DHA injection alone. These findings demonstrate the therapeutic potential of DHA in SCI, and clearly indicate that this fatty acid confers significant protection to the white matter.
Net Heterolytic Cleavage of B–H and B–B Bonds Across the N–Pd Bond in a Cationic (PNP)Pd Fragment (2011)

The use of weakly coordinating anions BAr(F)(4) (where Ar(F) = 3,5-(CF(3))(2)C(6)H(3)) and CB(11)H(12) allows one to access clean reactions of the [(PNP)Pd](+) fragment (PNP = bis(2-(i)Pr(2)P4-Me-phenyl)amido) with the B-H bond in catecholborane (CatBH) and catecholdiboron (CatBBCat). In both cases, a net heterolytic cleavage of B-H or B-B takes place, with the nitrogen atom of PNP being a recipient of a boryl fragment. The resultant products [(PN(BCat)P)PdH](+) (2) and [(PN(BCat)P)PdBCat](+) (3) were isolated as either BAr(F)(4) or CB(11)H(12) salts and fully characterized. They are susceptible to hydrolysis, with the B-N bond hydrolyzing selectively and rapidly at RT to give [(PN(H)P)PdH](+) (1) and [(PN(H)P)PdBCat](+) (4). Notably, 4 and 2 are isomers, but they do not interconvert even under thermolysis at 90 °C. The Pd-B bond in 4 can be further hydrolyzed more slowly, to give 1. On the other hand, a Pd-B bond was formed from the Pd-H bond in 2 by reaction with excess CatBH (and evolution of H(2)), producing 3.
Management of Acute Achilles Tendon Ruptures. (2021)

Acute Achilles tendon ruptures can be disabling injuries with high personal and societal costs. However, the decision to pursue operative versus nonoperative management following these injuries remains controversial. Functional rehabilitation techniques have been refined such that outcomes may be as good, if not better, with nonoperative treatment. Furthermore, while surgical treatment rates have dramatically decreased in many countries over the prior 15 years, operative repair remains the treatment of choice for most patients in the United States. A critical review is presented regarding outcomes, complications, and rates of return to sport for both pathways to determine the best course of action for patients who sustain this injury.
Switchability of a single port SAW resonator using the electrical Bragg band gap (2022)

A proof of concept of a new solution for achieving tunable SAW components based on the electrical Bragg band gap concept developed for piezoelectric phononic crystals is presented on a SAW resonator on a LiNbO3 substrate. In this work, it is shown that for a fixed geometry, it is possible to shift the main resonance frequency by modifying the electrical condition on the electrodes that constitute the cavity's mirrors. The concept was validated by both numerical simulations and experimental characterization of single port resonators fabricated on LiNbO3.
Determination of deformation accumulated under equally-channel angular pressing, taking into account its components (2018)

РќРѕРІС‹Рµ С‚РµС…РЅРѕР»РѕРіРёРё, РҐРёРјРёС‡РµСЃРєР°СЏ РїСЂРѕРјС‹С€Р»РµРЅРЅРѕСЃС‚СЊ, РҐРёРјРёС‡РµСЃРєР°СЏ С‚РµС…РЅРѕР»РѕРіРёСЏ, РќР°СѓС‡РЅС‹Рµ Р¶СѓСЂРЅР°Р»С‹, Р—Р°С‰РёС‚Р° РѕС‚ РєРѕСЂСЂРѕР·РёРё, РўРµС…РЅРѕР»РѕРіРёСЏ РјРµС‚Р°Р»Р»РѕРІ, РЎРІРѕР№СЃС‚РІР° РјР°С‚РµСЂРёР°Р»РѕРІ, РўРµС…РЅРёС‡РµСЃРєРёРµ Р¶СѓСЂРЅР°Р»С‹, РќР°СѓРєР° Рё С‚РµС…РЅРѕР»РѕРіРёРё, РЎРїСЂР°РІРѕС‡РЅР°СЏ Р»РёС‚РµСЂР°С‚СѓСЂР°, РќР°СѓС‡РЅС‹Рµ СЂР°Р·СЂР°Р±РѕС‚РєРё
Vitamin C utilization status in chronic alcoholic patients after short-term intravenous therapy. (1981)

Blood (leukocytic) ascorbic acid (vitamin C) levels were estimated in 25 chronic alcoholics (M = 21; F = 4; Age: mean +/- S.D. = 46.28 +/- 8.78; range 28-61 years) on admission before starting any treatment and on the sixth day following intravenous therapy with vitamin C -- 500 mg daily for 5 days. Twenty-four out of 25 patients (96%) were found to be deficient in blood vitamin C (mean +/- S.D. = 68.44 +/- 28.13; range = 28-148; normal range for control population = 120-300 nmol/10(8) W.B.C.). The status of blood vitamin C was significantly improved after the replenishment therapy with I/V vitamin C 500 mg daily for 5 days (mean +/- S.D. = 108.32 +/- 34.98 nmol/10(8) W.B.C.: range = 54-282.5; t = 3.76; P = less than 0.001). Still the levels did not return to within the normal range in 16 patients out of 25 (64%). In view of the biochemical deficiency of vitamin C in chronic alcoholics, it is suggested that conventional detoxification therapy for ethanol withdrawal syndrome should include polyvitamins including ascorbic acid. It is further suggested that more prolonged replenishment therapy with vitamin C, preferably by intravenous route, may be needed to normalize its blood levels in some chronic alcoholic patients.
Preparation of a monoclonal antibody against testosterone and its use in development of an immunochromatographic assay (2016)

A monoclonal antibody against testosterone was produced and used to construct an indirect enzyme-linked immunosorbent assay (ELISA) and immunochromatographic assay. As testosterone could not be linked to the protein directly, testosterone and methyltestosterone were first derived by using carboxymethoxylamine hemihydrochloride (CMO) to introduce a carboxyl group at the carbonyl group position. Then the resulting testosterone-3-CMO was coupled to the carrier protein to form the immunogen, using the 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC)/N-Hydroxysuccinimide (NHS) method. A cell line obtained by cell fusion secreted an antibody which showed high affinity with testosterone. Based on methyltestosterone-3-CMO-ovalbumin (OVA) as the competitive antigen, the ELISA we developed showed high sensitivity to testosterone, with IC50 of 0.11 ng/mL. The results of cross-reactivity testing showed that the antibody was specific to testosterone. Based on this antibody, an immunochromatographic assay was developed and used to detect testosterone in milk samples. This method could be used as a fast and cost-effective alternative tool for screening for endocrine-disrupting compounds.
Enhanced programming by demonstration through measurement of the stiffness of the human arm (2005)

status: Published