gebhart/patrepeval huggingface dataset:
Performance Evaluation in Multi-Rate, Multi-Hop Communication Networks with Adaptive Routing (1998)

Accurate performance evaluation has always been an important issue in network design and analysis. Discrete event simulation has been known to be accurate, but very time-consuming. Thus, analytical methods/approximation is necessary for real-time estimation, large-scale network optimization, and sensitivity analysis. In a circuit-switched loss network, a particular performance metric of interest is the end-to-end blocking probability. Various analytical approaches and approximation schemes have been suggested for this problem, and among them, the fixed-point method, or reduced load method, has received much attention. However, most of these schemes considered either only single traffic rate situations or multi-rate traffic under fixed routing. The authors have developed an approximation scheme to estimate end-to-end blocking probability in a multi-rate, multi-hop network with an adaptive routing scheme. The approximation results are compared with that of discrete event simulation. An example of application also is provided in which the proposed scheme is linked to the optimization tool CONSOL-OPTCAD to get network design trade-offs. The method described here is readily applicable to the accurate performance evaluation of military networks, which are often large and hybrid.
Advancing the automation of plant nucleic acid extraction for rapid diagnosis of plant diseases in space (2023)

Human space exploration missions will continue the development of sustainable plant cultivation in what are obviously novel habitat settings. Effective pathology mitigation strategies are needed to cope with plant disease outbreaks in any space-based plant growth system. However, few technologies currently exist for space-based diagnosis of plant pathogens. Therefore, we developed a method of extracting plant nucleic acid that will facilitate the rapid diagnosis of plant diseases for future spaceflight applications. The microHomogenizer<sup>™</sup> from Claremont BioSolutions, originally designed for bacterial and animal tissue samples, was evaluated for plant-microbial nucleic acid extractions. The microHomogenizer<sup>™</sup> is an appealing device in that it provides automation and containment capabilities that would be required in spaceflight applications. Three different plant pathosystems were used to assess the versatility of the extraction process. Tomato, lettuce, and pepper plants were respectively inoculated with a fungal plant pathogen, an oomycete pathogen, and a plant viral pathogen. The microHomogenizer<sup>™</sup>, along with the developed protocols, proved to be an effective mechanism for producing DNA from all three pathosystems, in that PCR and sequencing of the resulting samples demonstrated clear DNA-based diagnoses. Thus, this investigation advances the efforts to automate nucleic acid extraction for future plant disease diagnosis in space.
Procedure for quantitative 1H magnetic resonance spectroscopy and tissue characterization of human brain tissue based on the use of quantitative magnetic resonance imaging (2012)

The implemented method was fast, robust, and user-independent.
ChemInform Abstract: A General Approach to Unsymmetrical Tricoordinate Iodinanes: Single Step Preparation of Mixed Iodosobenzene Sulfonates PhI(X)OSO2R, via Reaction of Iodosobenzene with Me3SiX. (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Long-term benefits of targeted micronutrition with the holoBLG lozenge in house dust mite allergic patients (2022)

Summary Purpose The long-term effects of targeted micronutrition with the holoBLG lozenge in house dust mite (HDM) allergic rhinoconjunctivitis (ARC) patients were evaluated at a follow-up visit in an allergen exposure chamber (AEC). Methods Patients who were supplemented for 3‑months with the holoBLG lozenge in a previous study with two controlled HDM-AEC challenges [visits: V1, V3] were recruited for a third AEC challenge (V5) 7–8 months after cessation of supplementation. Symptoms (nose, conjunctival, bronchial, others), well-being, and lung function parameters were recorded exactly as in the previous study. Primary endpoint was change in median Total Nasal Symptom Score (TNSS) at V5 compared to V1. Secondary endpoints included e.g. change in median Total Symptom Score (TSS) and the exploratory analysis of temporal evolution of symptom scores using linear mixed effects models. Results Of the 32 patients included in the original study, 27 could be recruited for the follow-up visit with a third AEC challenge. An improvement of 20% ( p = 0.15) in the primary endpoint TNSS [V1: 2.5 (interquartile range [IQR]: 1–4), V5: 2.0 (IQR: 1–3)] was observed; 40% ( p = 0.04) improvement was seen for the TSS [V1: 5.0 (IQR: 3–9), V5: 3.0 (IQR: 2–5.5)]. Analysis of temporal evolution of all symptom scores, and the personal well-being revealed sustained, clinically meaningful improvement at V5 compared to V1. No relevant lung function parameter differences were observed. Conclusions Sustained long-term reduction of TNSS (primary endpoint) and sustained long-term improvement of secondary endpoints (temporal evolution of all symptom scores and well-being) were demonstrated 7–8 months after cessation of holoBLG supplementation, indicative of a long-lasting nature of immune resilience induced by holoBLG. Trial registration The study was registered at clinicaltrials.gov (NCT04872868).
Frequency response analysis on modified plant of extended state observer (2017)

The active disturbance rejection control (ADRC) framework gives birth to a new concept, the modified plant (MP), describing the dynamics after the total disturbance is estimated and cancelled approximately. Ideally the modified plant is in integral form, to greatly simplify and fix the controller design, even though actual plant contains higher-order dynamics or dead time. This paper investigates that when such processes are modified into the integral, how the parameters of the extended state observer (ESO) impact on the dynamic characteristics and stability of the MP. Frequency-domain analyses show that the MP can gradually approach the integral form through parameters tuning. However, it should be cautious that an aggressive set of parameters may lead to an unstable modified plant in the presence of order mismatch.
Preparation of Polypyrrole/Silver Conductive Polyester Fabric by UV Exposure (2020)

Abstract In this study, polypyrrole/silver (PPy/Ag) conductive polyester fabric was synthesized via an in-situ polymerization method under UV exposure, using silver nitrate (AgNO 3 ) as an oxidizing agent in the presence of sodium dodecyl benzene sulfonate (SDBS) and polyvinylpyrrolidone (PVP). The effect of the preparation processes on the properties of the conductive fabric was studied experimentally, and the optimal preparation process of the conductive fabric was obtained. X-ray photoelectron spectroscopy (XPS) and Fourier transform infrared (FTIR) showed the chemical structural properties of the PPy/Ag conductive polyester fabric. X-ray diffraction (XRD) confirmed the presence of silver nanoparticles in the prepared material. Furthermore, subsequent test results proved that the PPy/Ag conductive polyester fabric prepared by UV irradiation had good electrical conductivity and antibacterial property. The sheet resistance of the prepared conductive fabric was 61.54 Ω • sq −1 .
Is a Space Laundry Needed for Exploration (2014)

Future human space exploration missions will lengthen to years, and keeping crews clothed without a huge resupply burden is an important consideration for habitation systems. A space laundry system could be the solution; however, the resources it uses must be accounted for and must win out over the very reliable practice of bringing along enough spare underwear. Through NASA's Logistics Reduction and Repurposing project, trade off studies have been conducted to compare current space clothing systems, life extension of that clothing, traditional water based clothes washing and other sanitizing techniques. The best clothing system of course depends on the mission and assumptions, but in general, analysis results indicate that washing clothes on space missions will start to pay off as mission durations push past a year.
Inhomogeneous broadening of optically detected magnetic resonance of the ensembles of nitrogen-vacancy centers in diamond by interstitial carbon atoms (2015)

We study the impact of the negatively charged nitrogen-vacancy (NV–) center density on the lattice strain resulting in the splitting of the optically detected magnetic resonance of HPHT diamond. A simple model, taking into account the presence of the interstitial carbon atoms, acting like a wedge force on the crystal lattice, explains the broadening and splitting of the optically detected magnetic resonance of the ensemble of NV– centers at densities within the range of 1013 ÷ 1014 cm−3. This model uses a complete generalized spin Hamiltonian, takes into account the strain-effect of each center in the ensemble and gives good agreement with experimental data.
AMY plaques in familial AD (2000)

AMY plaques are consistently present in familial AD due to presenilin-1 (PS-1), PS-2, and amyloid precursor protein mutations, and they can begin to accumulate before the emergence of dementia.
A prototype functional language implementation for hierarchical- memory architectures. Revision 1 (1992)

Programming languages are the most important tool at a programmers` disposal. All other tools correct, visualize, or evaluate the product crafted by this tool. The advent of multiprocessor computer systems has greatly complicated the programmer`s task an increased his need for high-level languages capable of automatically taming these architectures. In this paper, we describe a prototype implementation of Sisal for multiprocessor, hierarchical-memory systems. The implementation includes explicit compiler and runtime control that effectively exploits the different levels of memory and manages interprocess communications (IPC). We give preliminary performance results for this system on the BBN TC2000.
The effect of ultrasound on the percutaneous absorption of lignocaine. (1985)

The influence of ultrasound on the percutaneous absorption of lignocaine from a cream base was investigated in a double-blind cross-over trial in healthy volunteers. Mean data indicated that there was a slightly faster onset time for local anaesthesia when ultrasound was administered when compared with control values (no ultrasound). However, the differences were not statistically significant. Further controlled clinical studies are required into the effect of ultrasound on percutaneous absorption since the technique (phonophoresis) has been alleged to enhance percutaneous penetration of a number of drugs.
An Application of Uplink Common Channel to Packet Relay in CDMA Radio Access Networks (2005)

Multihop techniques in CDMA radio access networks, enable dead-spot mobile stations, which cannot communicate with base stations directly, to send data to them via other mobile stations. In this paper, we propose a mechanism for establishing connections and relaying packets between mobile stations. In this mechanism, the mobile stations are connected to one another and relay packets through a random access channel, which is an uplink common channel. In addition, our mechanism satisfies the requirements for applying multihop techniques to third generation radio access networks. Moreover, we also discuss our evaluation of the performance of the mechanism through computer simulations. The results we obtained reveal that it is capable of reducing dead-spot mobile stations and improving throughput with only limited modifications to conventional systems. Furthermore, we propose an adaptive transmission power control to enhance our mechanism and also evaluate this method through computer simulations.
Controlled partial hydrolysis of spherosilicate frameworks: syntheses of endo-[(Me3SiO)6Si6O7(OH)4] and endo-[(Me3SiO)6Si6O7{OSiMe2(CHCH2)}4] from [(Me3SiO)6Si6O9] (1999)

Readily available (RMe2SiO)6Si6O9 (3 R = Me, 5 R = CHCH2); reacts cleanly with aqueous NEt4OH in THF to afford endo-C2h-(RMe2SiO)6Si6O7(OH)4 (7 R = Me, 9 R = CHCH2); exhaustive silylation of 7 with (CH2CH)- Me2SiCl/NEt3 affords endo-C2h-(Me3SiO)6Si6O7[OSiMe2(CHCH2)]4 (10).
[How I explore...a skin tumor in a transplant patient]. (2010)

Immunosuppressive therapy associated with organ transplant leads to an increased risk to develop skin cancers. In such circumstances, squamous cell carcinomas and basal cell carcinomas represent the most frequent tumors. Other neoplasms include malignant melanoma, Merkel cell carcinoma and Kaposi disease. Histopathology is primordial in the establishment of the diagnosis. In addition, bioengineering devices and skin imaging methods are useful in establishing the risk of cancers and for detecting incipient tumoral lesions.
A direct membrane filter method for enumerating somatic coliphages in drinking water. (1994)

The application of a simple membrane filter method to enumerate specific somatic bacteriophages of Escherichia coli, using E. coli C as host strain, from drinking water samples was studied. The efficiency of the method using cellulosic membrane filters, samples pretreated with magnesium ions and Tween 80 added to agar medium-host cell lawns ranged from 68.9 to over 112%, depending on the phage content of the sample. To avoid the pre-treatment of the sample with magnesium salts, electropositive-charged filters of cellulosic ester (HA-PEI and HA-Nalco) and Virosorb-1MDS filters were tested in conjunction with the simple membrane filter method. The electropositive filters showed wide bacteriophage recovery rate intervals depending on the sample treatment, ranging between 31.4 and 96.2% for ester-type filters, and a mean recovery lower than 2.2% for Virosorb filters. On the other hand, it was proved that the use of Tween 80 as an eluent improved somatic coliphage recovery rates for all the filters tested. In short, this methodology provides a rapid analysis (6-8 h) of the somatic coliphages from drinking water using the membrane filtration technique.
Open-Distributed SCADA System for the Okutataragi Power Station and Substation (1999)

The total supervisory control and data acquisition (SCADA) system has been developed for the Okutataragi Pumped Storage Power Station and its substation. The system applies an open distributed client-server computer architecture and the state-of-the-art man-machine devices, such as a large mimic displays and CRTs with mouse operation. It also includes the following operator support functions: a fault tree based operator guidance function, a bearing temperature prediction function, and a vibration monitoring function. The SCADA system has been put into commercial operation where its superior capabilities have allowed the entire power station and its substation to be run by only two operators.
Hackethal Bundle Nailing with Intramedullary Elastic Nails in the Treatment of Two- and Three-Part Fractures of the Proximal Humerus: Initial Experience at Al Razi Hospital, Kuwait (2009)

In cases of two-part fracture of the proximal humerus, the minimally invasive Hackethal technique alone and in cases of three-part fracture, the same technique with percutaneous cannulated screws provided excellent clinical and radiological results with a minimal risk of complication. It is an important alternative to open reduction and internal fixation of these difficult fractures.
Ultraporous Electron‐Depleted ZnO Nanoparticle Networks for Highly Sensitive Portable Visible‐Blind UV Photodetectors (2015)

A hierarchical nano- and microstructured morphology for visible-blind UV photo-detectors is developed, which provides record-high milliampere photocurrents, nanoampere dark currents, and excellent selectivity to ultralow UV light intensities. This is a significant step toward the integration of high-performance UV photodetectors in wearable devices.
Functional Covalent Layer-by-Layer Thin Films by [2 + 2] Cycloaddition–Retroelectrocyclization (2018)

Covalent layer-by-layer (LbL) thin films with the well-defined charge-transfer (CT) chromophores were fabricated by the highly efficient [2 + 2] cycloaddition-retroelectrocyclization (CA-RE) reaction between the dialkylaniline-substituted alkynes and 7,7,8,8-tetracyanoquinodimethane (TCNQ) moieties. The resulting thin films showed potent redox activities and Ag<sup>+</sup> ion sensing ability due to the formed CT chromophores.
Technology for Enhanced Oil Recovery using an Oil-Displacing Acidic System of Prolonged Action (2019)

An oil-displacing system of prolonged action with adjustable viscosity based on surfactant inorganic acid adduct and polyol is created with the purpose to increase the efficiency of flooding or thermal steam formation treatment and to enhance oil recovery. The laboratory studies of physicochemical, rheological, and filtration characteristics of the system under natural exploitation conditions and thermal-steam treatment are presented. In 2014-2018 the field tests of the technology for enhanced oil recovery were successfully carried out using an acid oil-displacing system at the experimental sites of the Permian-Carboniferous reservoir of the high-viscosity oil of the Usinsk oilfield.
Exploiting Oligo(amido amine) Backbones for the Multivalent Presentation of Coiled-Coil Peptides (2015)

The investigation of coiled coil formation for one mono- and two divalent peptide-polymer conjugates is presented. Through the assembly of the full conjugates on solid support, monodisperse sequence-defined conjugates are obtained with defined positions and distances between the peptide side chains along the polymeric backbone. A heteromeric peptide design was chosen, where peptide K is attached to the polymer backbone, and coiled-coil formation is only expected through complexation with the complementary peptide E. Indeed, the monovalent peptide K-polymer conjugate displays rapid coiled-coil formation when mixed with the complementary peptide E sequence. The divalent systems show intramolecular homomeric coiled-coil formation on the polymer backbone despite the peptide design. Interestingly, this intramolecular assembly undergoes a conformational rearrangement by the addition of the complementary peptide E leading to the formation of heteromeric coiled coil-polymer aggregates. The polymer backbone acts as a template bringing the covalently bound peptide strands in close proximity to each other, increasing the local concentration and inducing the otherwise nonfavorable formation of intramolecular helical assemblies.
938. A proton magnetic resonance study of Zeise's salt (1963)

S. Maričićać, C. R. Redpath and J. A. S. Smith, J. Chem. Soc., 1963, 4905 DOI: 10.1039/JR9630004905
DO CELL-PENETRATING PEPTIDES CROSS THE BLOOD-BRAIN BARRIER? (2014)

Cell-penetrating peptides (CPPs) are a chemically diverse group of peptides, able to cross cell membranes. In literature, several studies are available describing a successful coupling of a brain-impermeable compound to a CPP to transport the molecule across the blood-brain barrier (BBB). Quantitative kinetic BBB transport studies of cell-penetrating peptides are however not yet available. To characterize quantitatively the BBB behavior of CPPs, the in vivo BBB transport and the in vitro metabolic stability of a diverse set of CPPs was determined. The chemical-functional space of the CPPs was first explored using chemo-molecular descriptors and a newly defined cell-penetrating response [1]. Then, five chemically and functionally diverse CPPs were selected representing the CPP space. Their BBB influx and efflux was quantified, as well as their distribution to the brain capillaries and parenchyma. Furthermore, the in vitro metabolic stability of these CPPs in mouse serum and brain was determined to ensure the reliability of our BBB transport conclusions. Finally, preliminary results of the in-brain region distribution will be presented. Our results indicate that the investigated CPPs show divergent BBB transport kinetics, which may be explained by their structural difference and their mechanism of cellular influx.
[Difficulties in fixing the official dosage of drugs in children]. (1989)

In the French Pharmacopoeia there is a table of doses of drugs for pediatric use, which is to be hold as an official document. Some of the problems raised for establishing these doses are discussed in this paper: choice of age-ranges, selection of drugs, way of expressing doses, interest or not to indicate maximal doses, spread of these data to medical prescribers and pharmacists.
Mummification of the infarcted myocardium by high dose corticosteroids. (1978)

There is evidence that glucocorticoids reduce infarct size but their use in myocardial infarction remains controversial because of their potential adverse effects on healing of the infarct. To investigate the healing process, rats received either four parenteral doses of 50 mg/kg of methylprednisolone (MP) or saline 5 min, 3,6 and 24 hr after coronary occlusion and their hearts were examined by light and electron microscopy 48 hr and seven days after occlusion. At 48 hr, in five untreated rats, only 12 +/- 7% of injured myocytes showed the persistence of striations and a relatively intact sarcolemma despite loss of nuclei and hence appeared "mummified" whereas in six MP-treated rats 72 +/- 8% of myocytes exhibited this appearance (P less than 0.001). In treated rats there were fewer phagocytes than in controls. At seven days, in seven MP-rats, mummified cells were still more prominent than in five untreated rats and there were fewer phagocytes and less collagen. In conclusion, high dose of MP delays the inflammatory process and retards the disintegration of necrotic myocytes, resulting in impaired healing.
Cancer Patients' Long-term Experiences of Participating in a Comprehensive Lifestyle Intervention Study While Receiving Chemotherapy (2018)

Our findings encourage the future implementation of lifestyle interventions during cancer treatment, even in cancer patients with advanced disease. However, when implementing lifestyle interventions, healthcare professionals must keep the patients' motivation, perceived ability to adhere to lifestyle recommendations, and individual needs in mind.