gebhart/patrepeval huggingface dataset:
η2 Coordination of Electron-Deficient Arenes with Group 6 Dearomatization Agents (2020)

The exceptionally <i>π</i>-basic metal fragments {MoTp-(NO)(DMAP)} and {WTp(NO)(PMe<sub>3</sub>)} (Tp = tris(pyrazolyl)borate; DMAP = 4-(<i>N</i>,<i>N</i>-dimethylamino)pyridine) form thermally stable <i>η</i> <sup>2</sup>-coordinated complexes with a variety of electron-deficient arenes. The tolerance of substituted arenes with fluorine-containing electron withdrawing groups (EWG; -F, -CF<sub>3</sub>, -SF<sub>5</sub>) is examined for both the molybdenum and tungsten systems. When the EWG contains a <i>π</i> bond (nitriles, aldehydes, ketones, ester), <i>η</i> <sup>2</sup> coordination occurs predominantly on the nonaromatic functional group. However, complexation of the tungsten complex with trimethyl orthobenzoate (PhC(OMe)<sub>3</sub>) followed by hydrolysis allows access to an <i>η</i> <sup>2</sup>-coordinated arene with an ester substituent. In general, the tungsten system tolerates sulfur-based withdrawing groups well (e.g., PhSO<sub>2</sub>Ph, MeSO<sub>2</sub>Ph), and the integration of multiple electron-withdrawing groups on a benzene ring further enhances the <i>π</i>-back-bonding interaction between the metal and aromatic ligand. While the molybdenum system did not form stable <i>η</i> <sup>2</sup>-arene complexes with the sulfones or ortho esters, it was capable of forming rare examples of stable <i>η</i> <sup>2</sup>-coordinated arene complexes with a range of fluorinated benzenes (e.g., fluorobenzene, difluorobenzenes). In contrast to what has been observed for the tungsten system, these complexes formed without interference of C-H or C-F insertion.
[Characteristics of the reaction of the embryonic hepatocyte to the effect of insulin and adrenaline]. (1982)

Adrenaline (10-6 g/ml) and insulin (10-6-8 IE/ml) cause changes of the acid DNase and phosphatase activity in hepatic cells of rat embryos on the 20th day of development. Adrenaline stimulates granular endoplasmatic reticulum development, increases the number and size of lysosomes, breaks their integrity. Insulin practically has no effect on the DNase activity, but labilizes the lysosome membrane.
Analytical solution for photonic band-gap crystals using Drude conductivity (2004)

An analytical solution for the photonic band-gap of semiconductor structures in the terahertz (THz) frequency range is discussed. In analogy with the Kronig–Penney model for electronic band-gaps in periodic potentials, Maxwell’s equations for the propagation of light in the photonic crystal are transformed into an equivalent form of Schrödinger’s equation. In the THz frequency range, the refractive index of the semiconductor is well represented by a frequency-dependent Drude model. We thus find a Kronig–Penney type solution for the photonic band-gap crystal.
Geometrical impact on the optical polarization of droplet epitaxial quantum dots (2012)

We report on experimental and theoretical investigations of the optical anisotropy of GaAs/AlGaAs quantum dots grown by droplet epitaxy. With in situ annealing in the growth, the shape of quantum dots is systematically controlled from a tall and laterally symmetric shape to a flat and laterally elongated one. Photoluminescence spectroscopy demonstrates an uncommon observation: the more elongated the quantum dots, the lower the degree of linear polarization. Theoretical analysis based on a four-band $\mathbf{k}\ifmmode\cdot\else\textperiodcentered\fi{}\mathbf{p}$ theory reveals a substantial impact of vertical confinement on the valence heavy-hole and light-hole mixing, which leads to the enhancement of polarization anisotropy for taller quantum dots. The influence of Coulomb interactions on polarization anisotropy is studied by using the partial configuration interaction method, and is shown to reduce the polarization anisotropy through the mixing of single-particle configurations with different symmetries.
Hearing Nano-Structures: A Case Study in Timbral Sonification (2012)

Presented at the 18th International Conference on Auditory Display (ICAD2012) on June 18-21, 2012 in Atlanta, Georgia.
Recent Advances in High Cell Density Cultivation for Production of Recombinant Protein (2008)

This paper reviews recent strategies used for increasing specific yield and productivity in high cell density cultures. High cell density cultures offer an efficient means for the economical production of recombinant proteins. However, there are still some challenges associated with high cell density cultivation (HCDC) techniques. A variety of strategies in several aspects including host design consideration, tuning recombinant protein expression, medium composition, growth methodologies, and even control and analysis of the process have been successfully employed by biotechnologists to increase yield in high cell density cultures. Although most researches have focused on Escherichia coli, other microorganisms have the potential to be grown at high density and need further investigation. In recent years, information on physiological changes of hosts during different phases of cultivation derived from functional genomics, transcriptomics and proteomics is being used to overcome the obstacles encountered in high cell density cultivation and hence increase productivity.
25 A NEW IN-VITRO MODEL FOR HEAD TRAUMA (1999)

*Dpartment of Anesthisiology. Technical Unversity Munick, Munick, Germany †Department of Meseremenss-. Comerl- and Microchaiqess, University of Ulm †Department of Anesthesiology University Hospital of Ulm, Ulm, Germany.
FISCHER-TROPSCH SYNTHESIS OVER IRON CATALYSTS: THE USE OF REACTIVE SCAVENGERS TO IDENTIFY REACTION INTERMEDIATES. (1982)

The synthesis of hydrocarbons from H/sub 2/ and CO was studied on a silica-supported iron catalyst. The synthesis was carried out at 1.54 atmospheres and 200 to 255/sup 0/C in a differential reactor. The working catalyst is realized by transforming Fe/sub 2/O/sub 3/ into a mixture of bulk carbides and iron under synthesis conditions. After the catalyst achieves a steady state condition pulses of a helium stream saturated with pyridine are injected into the reactant gas mixture. The reactor effluent is found to contain alkylpyridines. These are argued to result from pyridine reacting with the alkyl fragments which are formed on the catalyst surface from H/sub 2/ and CO. The distribution of alkylpyridines is related to the synthesis product distribution as a means of gaining insight into the synthesis mechanism. 10 figures, 1 table.
Multiscale Scattering For Audio Classification. (2011)

[TODO] Add abstract here.
Broadband Class-F Power Amplifiers for Handset Applications (2009)

This paper presents an efficient farfield simulation, exploiting and linking the strength of three commercial simulation tools. For many practical array and multiport antenna designs it is essential to examine the farfield for a general port excitation or termination scenario. Some examples are phased array designs, problems related to mutual coupling and scan blindness, tuning of parasitic elements, MIMO antennas and correlation. The proposed method fully characterizes the nearfield and the farfield of the antenna, so to compute farfield patterns by means of superposition for any voltage/current state at the port terminals. A recently published low-cost patch antenna phased array with analog beam steering by another group was found very suitable to demonstrate the proposed method.
Development of a Regional Public Transportation GIS Architecture and Data Model (2012)

Coordinated data sharing is important for government jurisdictions that overlap the same geographic area. For efficient planning and operations purposes, each jurisdiction should have knowledge of the other organizations' activities that may affect them. Florida Department of Transportation (FDOT) District 7 (D7) has identified the need to obtain and view spatial data from many public transportation agencies within FDOT D7 and across the West Central Florida region. This ability will greatly increase the efficiency of FDOT D7 employees that use public transportation information in their workflows. Furthermore, it will assist the regional public transportation planning efforts in FDOT D7. Past efforts for intra-regional data sharing have included the manual transmission of datasets via email or File Transfer Protocol. However, manual data sharing is difficult to sustain at a high frequency due to the manual effort involved in collecting, formatting, sending, receiving, and processing the data. Additionally, each dataset may be in a different format, which makes comparison and coordination among agency datasets difficult and time-consuming. If the perceived effort to exchange data is too great, old and outdated datasets may be used in place of new data, even if new data are available. The research team, along with feedback from FDOT D7 and the transit agencies in its region, successfully developed and demonstrated a prototype software system that is able to automatically retrieve General Transit Feed Specification (GTFS)-based datasets (describing transit stops, routes, and schedules) from local transit agency websites and store them in the FDOT D7 enterprise geodatabase. Additionally, a Web application was developed to visualize and query transit data alongside FDOT D7 data. The resulting Web application is capable of showing multimodal data for the regional transportation systems that is always based on the most recent data available from the transit agency. Challenges encountered in this project included working with proprietary Environmental Systems Research Institute (ESRI) software that has limited examples and documentation and coordinating with transit agencies that are in various stages of collecting and maintaining their bus stop inventory data. Next steps for this project are the deployment of the system to FDOT D7 staff as well as replication of this system to other districts, such as FDOT District 1. Tools exist to assist transit agencies in developing an accurate bus stop inventory and in creating and maintaining GTFS datasets. Increasing the awareness and expertise of agencies in the use of these tools will be useful for deploying this system with data from additional agencies. v 17.
Functional Consequences of a Rod Outer Segment Membrane Guanylate Cyclase (ROS-GC1) Gene Mutation Linked with Leber's Congenital Amaurosis (1998)

ROS-GC1 is the original member of the subfamily of membrane guanylate cyclases with two Ca2+ switches, which have been defined as CRM1 and CRM2. These are separately located within the intracellular domain of the cyclase. CRM1 switches on the enzyme at nanomolar concentrations of Ca2+ and is linked with phototransduction; the other stimulates at micromolar Ca2+ concentrations and is predicted to be linked with retinal synaptic activity. Ca2+ acts indirectly via Ca2+-binding proteins, GCAP1 and CD-GCAP. GCAP1 is a modulator of the CRM1 switch, and CD-GCAP turns on the CRM2 switch. A Leber's congenital amaurosis, termed LCA1, involves F514S point mutation in ROS-GC1. The present study shows that the mutation severely damages its intrinsic cyclase activity and inactivates its CRM1 switch but does not affect the CRM2 switch. In addition, on the basis of the established modulatory features of ROS-GC1, it is predicted that, in two other forms of LCA1 involving deletion of nt 460C or 693C, there is a frameshift in ROS-GC1 gene, which results in the nonexpression of the cyclase. For the first time, the findings define the linkage of distinct molecular forms of LCA to ROS-GC1 in precise biochemical terms; they also explain the reasons for the insufficient production of cyclic GMP in photoreceptors to sustain phototransduction, which ultimately leads to the degeneration of the photoreceptors.
Named data aggregation in wireless sensor networks (2014)

In this paper, we present a novel named data aggregation method dedicated to wireless sensor networks. The method relies on an adaptation of the CCNx protocol implementation that we have extended with in-network processing functions to aggregate named data efficiently. We have implemented and tested our solution with the Contiki operating system which is an operating system for resources-constrained embedded systems and wireless sensor networks. Our simulation and measurement results using the Cooja simulator and physical nodes show that our solution has a small overhead in terms of exchanged messages and provides acceptable data retrieval delays.
A 270-kb/s 35-mW modulator IC for GSM cellular radio hand-held terminals (1990)

The modulator IC is a mixed analog/digital transceiver component in a chip set that is designed for the hand-held terminals of the pan-European 900-MHz Groupe Special Mobile (GSM) digital cellular radio network. The concept of the radio-frequency environment in which the circuit is used is explained, focusing on the differences in existing systems. The architecture and different functions of the modulator circuit and details of the digital and analog processing in the transmission mode are discussed. The receiving mode, which is mostly based on analog processing, is highlighted. The device generates Gaussian minimum-shift-keying (GMSK) modulation and converts the received signal to 8-b words after filtering. The modulator IC uses digital waveform generation and a quadrature signal representation. This device is implemented in a 1.5- mu m CMOS technology. The power consumption is less than 35 mW from a 5-V supply.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Automatic array jet dispensing system based on visual system (2015)

Array jet dispensing technique plays an important role in micro assembly, especially for parts with different materials. An automatic array jet dispensing system was developed in this paper for micro inertial devices assembly. In order to have uniform original drop position of the adhesive array and easy monitoring, a machine vision module was integrated. The image processing and coordinate transformation were carried out to calibrate and compensate the system. The experimental results show that the position accuracy of the automatic array jet dispensing system was 10.7 μm, and minimum diameter of adhesive drops was 1.20 mm. A 8×8 array jet dispensing was obtained, the R-square for adhesive array was 0.953 while the standard deviation was 3.26%, which can meet the requirement of small inertial devices assembly. The dispensing properties on substrates of different material were also studied. All these research work provide the experimental basis for high precision micro jet dispersion technique.
Regulation of the renin-angiotensin system in coronary atherosclerosis: a review of the literature. (2007)

Activation of the renin-angiotensin system (RAS) is significant in the pathogenesis of cardiovascular disease and specifically coronary atherosclerosis. There is strong evidence that the RAS has effects on the mechanisms of action of atherosclerosis, including fibrinolytic balance, endothelial function, and plaque stability. Pharmacological inhibition of the renin angiotensin system includes angiotensin converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), and renin inhibitors. These agents have clinical benefits in reducing morbidity and mortality in the management of hypertension. In addition, ACE inhibitors and ARBs have shown to be effective in the management of congestive heart failure and acute myocardial infarction. This review article discusses the biochemical and molecular mechanisms involving the RAS in coronary atherosclerosis as well as the effects of RAS inhibition in clinical studies involving coronary atherosclerosis.
Fixed Point Quantization of Deep Convolutional Networks (2015)

In recent years increasingly complex architectures for deep convolution networks (DCNs) have been proposed to boost the performance on image recognition tasks. However, the gains in performance have come at a cost of substantial increase in computation and model storage resources. Fixed point implementation of DCNs has the potential to alleviate some of these complexities and facilitate potential deployment on embedded hardware. In this paper, we propose a quantizer design for fixed point implementation of DCNs. We formulate and solve an optimization problem to identify optimal fixed point bit-width allocation across DCN layers. Our experiments show that in comparison to equal bit-width settings, the fixed point DCNs with optimized bit width allocation offer &gt;20% reduction in the model size without any loss in accuracy on CIFAR-10 benchmark. We also demonstrate that fine-tuning can further enhance the accuracy of fixed point DCNs beyond that of the original floating point model. In doing so, we report a new state-of-the-art fixed point performance of 6.78% error-rate on CIFAR-10 benchmark.
Bilayer Al wire-grids as broadband and high-performance polarizers (2006)

We have fabricated, characterized and theoretically analyzed the performance of bilayer (or stacked) metallic wire-grids. The samples with 100 nm period were fabricated with extreme-ultraviolet interference lithography. Transmission efficiency over 50% and extinction ratios higher than 40 dB were measured in the visible range with these devices. Simulations using a finite-difference time-domain algorithm are in agreement with the experimental results and show that the transmission spectra are governed by Fabry-Perot interference and nearfield coupling between the two layers of the structure. The simple fabrication method involves only a single lithographic step without any etching and guarantees precise alignment and separation of the two wire-grids with respect to each other.
Engineered Si Sandwich Electrode: Si Nanoparticles/Graphite Sheet Hybrid on Ni Foam for Next-Generation High-Performance Lithium-Ion Batteries (2015)

Si-based electrodes for lithium ion batteries typically exhibit high specific capacity but poor cycling performance. A possible strategy to improve the cycling performance is to design a novel electrode nanostructure. Here we report the design and fabrication of Ni/Si-nanoparticles/graphite clothing hybrid electrodes with a sandwich structure. An efficient dip-coating of Si-NPs combined with carbon deposition was adopted to synthesize the unique architecture, where the Si-NPs are sandwiched between the Ni matrix and the graphite clothing. This material architecture offers many critical features that are desirable for high-performance Si-based electrodes, including efficient ion diffusion, high conductivity, and structure durability, thus ensuring the electrode with outstanding electrochemical performance (reversible capacity of 1800 mA h g(-1) at 2 A g(-1) after 500 cycles). In addition, the hybrid anode does not require any polymeric binder and conductive additives and holds great potential for application in Li-ion batteries.
Study of the Origin of Three Dimensional Structures in Shear Flows through External Forcing (1990)

Abstract : Experiments on an externally forced free shear layer are performed which study the origin of three-dimensional structures and chaos in shear flows. Transition routes between the laminar two dimensional stages of shear flows and their final complex three dimensional stages are examined. Two avenues of investigation are pursued. First, the general idea of a multi-frequency route to chaos is examined which treats the shear flow as an open dynamical system. An attempt is made to apply concepts from nonlinear dynamics to these systems Secondly, a new approach to generating three-dimensional structures in shear flows which involves the creation of a spatial shear in the frequency of external perturbations is presented. In these experiments, a variety of vortex reconnection behaviors is observed at the discontinuity.
Structure and interaction of point defects in transition-metal nitrides (2007)

Transition-metal nitrides (TMNs) are used in a variety of applications because of their renowned hardness and stability. Departure from the nominal 1:1 stoichiometry is often observed for TMNs and, therefore, defects have a prevalent role on TMN physical properties. Here, we report the results of first-principles calculations on nitrogen and metal point defects in the prototype system of TiN and in HfN and ZrN. We find features which are common to all systems, while we unravel also key differences. In certain cases---for example, N interstitials in TiN---the interaction between defects is attractive and it favors the formation of defect complexes. Other defects, like N interstitials in HfN and ZrN, do not pair up. We also present results on the effect of point defects on the electronic properties of TiN. Finally, we discuss pertinent experimental data and the implications of our findings on the thermal stability of TMN films.
Data from Inhibition of Akt Enhances the Chemopreventive Effects of Topical Rapamycin in Mouse Skin (2023)

&lt;div&gt;Abstract&lt;p&gt;The PI3Kinase/Akt/mTOR pathway has important roles in cancer development for multiple tumor types, including UV-induced nonmelanoma skin cancer. Immunosuppressed populations are at increased risk of aggressive cutaneous squamous cell carcinoma (SCC). Individuals who are treated with rapamycin (sirolimus, a classical mTOR inhibitor) have significantly decreased rates of developing new cutaneous SCCs compared with those that receive traditional immunosuppression. However, systemic rapamycin use can lead to significant adverse events. Here, we explored the use of topical rapamycin as a chemopreventive agent in the context of solar-simulated light (SSL)-induced skin carcinogenesis. In SKH-1 mice, topical rapamycin treatment decreased tumor yields when applied after completion of 15 weeks of SSL exposure compared with controls. However, applying rapamycin during SSL exposure for 15 weeks, and continuing for 10 weeks after UV treatment, increased tumor yields. We also examined whether a combinatorial approach might result in more significant tumor suppression by rapamycin. We validated that rapamycin causes increased Akt (S473) phosphorylation in the epidermis after SSL, and show for the first time that this dysregulation can be inhibited &lt;i&gt;in vivo&lt;/i&gt; by a selective PDK1/Akt inhibitor, PHT-427. Combining rapamycin with PHT-427 on tumor prone skin additively caused a significant reduction of tumor multiplicity compared with vehicle controls. Our findings indicate that patients taking rapamycin should avoid sun exposure, and that combining topical mTOR inhibitors and Akt inhibitors may be a viable chemoprevention option for individuals at high risk for cutaneous SCC. &lt;i&gt;Cancer Prev Res; 9(3); 215–24. ©2016 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;
Bioactive injectable hydrogel conjugated with a synthetic peptide for bone regeneration (2016)

Frontiers Events is a rapidly growing calendar management system dedicated to the scheduling of academic events. This includes announcements and invitations, participant listings and search functionality, abstract handling and publication, related events and post-event exchanges. Whether an organizer or participant, make your event a Frontiers Event!