gebhart/patrepeval huggingface dataset:
Mono-metalation of 9-Phenylcarbazole (1941)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMono-metalation of 9-PhenylcarbazoleHenry Gilman, C. G. Stuckwisch, and A. R. KendallCite this: J. Am. Chem. Soc. 1941, 63, 6, 1758–1759Publication Date (Print):June 1, 1941Publication History Published online1 May 2002Published inissue 1 June 1941https://pubs.acs.org/doi/10.1021/ja01851a504https://doi.org/10.1021/ja01851a504research-articleACS PublicationsRequest reuse permissionsArticle Views135Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Highly CO2-Selective Organic Molecular Cages: What Determines the CO2 Selectivity (2011)

A series of novel organic cage compounds 1-4 were successfully synthesized from readily available starting materials in one-pot in decent to excellent yields (46-90%) through a dynamic covalent chemistry approach (imine condensation reaction). Covalently cross-linked cage framework 14 was obtained through the cage-to-framework strategy via the Sonogashira coupling of cage 4 with the 1,4-diethynylbenzene linker molecule. Cage compounds 1-4 and framework 14 exhibited exceptional high ideal selectivity (36/1-138/1) in adsorption of CO(2) over N(2) under the standard temperature and pressure (STP, 20 °C, 1 bar). Gas adsorption studies indicate that the high selectivity is provided not only by the amino group density (mol/g), but also by the intrinsic pore size of the cage structure (distance between the top and bottom panels), which can be tuned by judiciously choosing building blocks of different size. The systematic studies on the structure-property relationship of this novel class of organic cages are reported herein for the first time; they provide critical knowledge on the rational design principle of these cage-based porous materials that have shown great potential in gas separation and carbon capture applications.
Metabolomics profile comparisons of irradiated and nonirradiated stored donor red blood cells (2014)

Background Understanding the metabolites that are altered by donor red blood cell ( RBC ) storage and irradiation may provide insight into the metabolic pathways disrupted by the RBC storage lesion. Study Design and Methods Patterns of metabolites, representing more than 11,000 distinct mass‐to‐charge ratio ( m / z ) features, were compared between gamma‐irradiated and nonirradiated CPDA ‐1–split RBC s from six human donors over 35 days of storage using multilevel sparse partial least squares discriminant analysis (ms PLSDA ), hierarchical clustering, pathway enrichment analysis, and network analysis. Results In ms PLSDA analysis, RBC units stored 7 days or fewer (irradiated or nonirradiated) showed similar metabolomic profiles. By contrast, donor RBC s stored 10 days or more demonstrated distinct clustering as a function of storage time and irradiation. Irradiation shifted metabolic features to those seen in older units. Hierarchical clustering analysis identified at least two clusters of metabolites that differentiated between RBC units based on storage time and irradiation exposure, confirming results of the ms PLSDA analysis. Pathway enrichment analysis, used to map the discriminatory biochemical features to specific metabolic pathways, identified four pathways significantly affected by irradiation and/or storage including arachidonic acid (p = 3.3 × 10 −33 ) and linoleic acid (p = 1.61 × 10 −11 ) metabolism. Conclusion RBC storage under blood bank conditions produces numerous metabolic alterations. Gamma irradiation accentuates these differences as the age of blood increases, indicating that at the biochemical level irradiation accelerates metabolic aging of stored RBC s. Metabolites involved in the cellular membrane are prominently affected and may be useful biomarkers of the RBC storage lesion.
Syndiotactic polypropylene nanofibers obtained from solution electrospinning process at ambient temperature (2015)

ABSTRACT Fabrication of semicrystalline syndiotactic polypropylene (sPP) nanofibers by solution electrospinning was studied. It was found that sPP nanofibers with an average diameter of 230 nm were successfully fabricated via solution electrospinning with methylcyclohexane as solvent at room temperature (25°C). The obtained diameter was significantly thinner than the minimum diameter of 350 nm of PP fibers that were reported previously. It was also found that increasing viscosity of the sPP solution, which was customarily a useful way of fabricating noncrystalline thin fibers, was found ineffectual in producing thinner semicrystalline sPP fibers in our experiments. In fact, a careful selection of solvent by considering the evaporation rate and the specific viscosity could effectively lead to the fabrication of thinner sPP fibers by imposing proper elongation and preventing the sPP solution from gelation. The results could be applied to other semicrystalline polyolefins with similar gelation characteristics analogous to sPP to produce thinner nanofibers. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016 , 133 , 43238.
On the estimation and compensation of IQ impairments in direct conversion transmitters (2008)

Compensating IQ impairments in transmitters is an important prerequisite for linearizing power amplifiers (PApsilas) by means of digital predistortion of the input signal. As the effects of gain- and phase imbalance and DC offset are increasing with the bandwidth of a transmitter, they must be corrected for because otherwise digital predistortion for PApsilas becomes ineffective. An important implementation aspect for many impairment correction schemes is the realization of the required feedback loop including the downconversion from the RF- to the baseband domain. We propose an IQ and DC offset estimation and compensation method which uses a simple detector diode in the feedback path. The characteristic of the detector diode needs not to be known, which makes implementation easy. It is shown by simulation and measurements, that the method works excellent for narrowband as well as for wideband signals.
ChemInform Abstract: SYNTHESIS AND STABILITY OF N‐NITROSO DIPEPTIDES (1985)

Abstract Die Amide (I) werden zu den Verbindungen (II) nitrosiert, deren Debenzylierung die Carbonsäuren (III) liefert.
Demonstration of Frequency Stability limited by Thermal Fluctuation Noise in Silicon Nitride Nanomechanical Resonators (2022)

The frequency stability of nanomechanical resonators (NMR) dictates the performance level of many state-of-the-art sensors (e.g., mass, force, temperature, radiation) that relate an external physical perturbation to a resonance frequency shift. While this is obviously of fundamental importance, accurate models and understandings of sources of frequency instability are not always available. The contribution of thermomechanical noise to frequency stability has been well studied in recent years and is often the fundamental performance limitation. Frequency stability limited by thermal fluctuation noise has attracted less interest but is nevertheless of fundamental importance notably in temperature sensing applications. In particular, temperature-sensitive NMR have become promising candidates for replacing traditional bolometers in infrared radiation sensing. However, reaching the ultimate detectivity limit of thermal radiation sensors requires their noise to be dominated by fundamental thermal fluctuation, which has not been demonstrated to date. In this work, we first develop a theoretical model for computing the frequency stability of NMR by considering the effect of both additive phase noise (i.e., thermomechanical, and experimental detection noise) and thermal fluctuation noise in a close-loop frequency tracking scheme. We thereafter validate this model experimentally and observe thermal fluctuation noise in SiN drum resonators of various sizes. Our work shows that by using resonators of specific characteristics--such as high temperature sensitivity, high mechanical quality factors, and high mass-to-thermal-conductance ratio--one can minimize additive phase noise below thermal fluctuation noise. This paves the way for NMR-based radiation sensors that can reach the fundamental detectivity limit of thermal radiation sensing and outperform existing technologies.
A submicroscopic translocation, t(4;10), responsible for recurrent Wolf-Hirschhorn syndrome identified by allele loss and fluorescent in situ hybridisation. (1992)

A 2 year old girl presented with developmental delay and subtle dysmorphic features suggestive of Wolf-Hirschhorn syndrome (WHS). High resolution chromosome analysis was normal in the child and both parents. Molecular analysis indicated that the child had not inherited a maternal allele of probes from 4p16, confirming the clinical diagnosis. Prenatal diagnosis in the next pregnancy showed that again the fetus had no maternal allele for probes mapping to 4p16. Fluorescent in situ hybridisation in the mother showed a submicroscopic translocation, t(4;10). A normal karyotype in a child with clinical features of WHS is an indication for further investigation.
Research data supporting "A Trapped Field of 14.3 T in Y-Ba-Cu-O Bulk Superconductors Fabricated by Buffer-Assisted Seeded Infiltration and Growth" (2018)

Data supporting the publication. The enclosed data set contains raw data connected with measurements relating to trapped field a a function of applied field, temperature as a function of time, tensile strength as measured by Brazillian technique for TSMG and TSIG processed YBCO samples.
Recombinant human erythropoietin in the anemia associated with multiple myeloma or non-Hodgkin's lymphoma: dose finding and identification of predictors of response (1995)

Previous phase I-II clinical trials have shown that recombinant human erythropoietin (rHuEpo) can ameliorate anemia in a portion of patients with multiple myeloma (MM) and non-Hodgkin's lymphoma (NHL). Therefore, we performed a randomized controlled multicenter study to define the optimal initial dosage and to identify predictors of response to rHuEpo. A total of 146 patients who had hemoglobin (Hb) levels < or = 11 g/dL and who had no need for transfusion at the time of enrollment entered this trial. Patients were randomized to receive 1,000 U (n = 31), 2,000 U (n = 29), 5,000 U (n = 31), or 10,000 U (n = 26) of rHuEpo daily subcutaneously for 8 weeks or to receive no therapy (n = 29). Of the patients, 84 suffered from MM and 62 from low- to intermediate-grade NHL, including chronic lymphocytic leukemia; 116 of 146 (79%) received chemotherapy during the study. The mean baseline Hb level was 9.4 +/- 1.0 g/dL. The median serum Epo level was 32 mU/mL, and endogenous Epo production was found to be defective in 77% of the patients, as judged by a value for the ratio of observed-to-predicted serum Epo levels (O/P ratio) of < or = 0.9. An intention-to-treat analysis was performed to evaluate treatment efficacy. The median average increase in Hb levels per week was 0.04 g/dL in the control group and -0.04 (P = .57), 0.22 (P = .05), 0.43 (P = .01), and 0.58 (P = .0001) g/dL in the 1,000 U, 2,000 U, 5,000 U, and 10,000 U groups, respectively (P values versus control). The probability of response (delta Hb > or = 2 g/dL) increased steadily and, after 8 weeks, reached 31% (2,000 U), 61% (5,000 U), and 62% (10,000 U), respectively. Regression analysis using Cox's proportional hazard model and classification and regression tree analysis showed that serum Epo levels and the O/P ratio were the most important factors predicting response in patients receiving 5,000 or 10,000 U. Approximately three quarters of patients presenting with Epo levels inappropriately low for the degree of anemia responded to rHuEpo, whereas only one quarter of those with adequate Epo levels did so. Classification and regression tree analysis also showed that doses of 2,000 U daily were effective in patients with an average platelet count greater than 150 x 10(9)/L. About 50% of these patients are expected to respond to rHuEpo. Thus, rHuEpo was safe and effective in ameliorating the anemia of MM and NHL patients who showed defective endogenous Epo production. From a practical point of view, we conclude that the decision to use rHuEpo in an individual anemic patient with MM or NHL should be based on serum Epo levels, whereas the choice of the initial dosage should be based on residual marrow function.
Development of a Portable and Automated Electrophoresis Based System forin-field Toxin Detection: "HABLab". (2008)

Abstract not provided.
Enhancement of EUV reflective multilayer properties by the insertion of Ru barrier layer (2002)

Although there are several ways to ensure the high throughput of EUVL process, increasing the EUV reflectivity of the multilayer mirror might be the simplest but still efficient solution for that. Many works to enhance the multilayer reflectivity have been reported and a good deal of them is related to the addition of barrier layers, such as B/sub 4/C and C into Mo/Si multilayer stack. Also, there was a try of sub-multilayering of Mo with Ru insertion to reduce the multilayer stress. In our experiment, we inserted Ru into Mo/Si multilayer to improve the optical property.
Late-Onset Epilepsy With Unknown Etiology: A Pilot Study on Neuropsychological Profile, Cerebrospinal Fluid Biomarkers, and Quantitative EEG Characteristics (2020)

<b>Introduction:</b> Despite the fact that epilepsy has been associated with cognitive decline, neuropsychological, neurobiological, and neurophysiological features in patients with late-onset epilepsy of unknown etiology (LOEU) are still unknown. This cross-sectional study aims to investigate the neuropsychological profile, cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD), and resting-state quantitative electroencephalographic (qEEG) cortical rhythms in LOEU patients with mild cognitive impairment (LOEU-MCI) and with normal cognition (LOEU-CN), compared to non-epileptic MCI (NE-MCI) and cognitively normal (CN) controls. <b>Methods:</b> Consecutive patients in two clinical Units diagnosed with LOEU-CN (19), LOEU-MCI (27), and NE-MCI (21) were enrolled, and compared to age and sex-matched cognitively normal subjects CN (11). Patients underwent standardized comprehensive neuropsychological evaluation and CSF core AD biomarkers assessment (i.e., CSF Aβ42, phospho-tau and total tau, classified through A/T/(N) system). Recordings of resting-state eyes-closed electroencephalographic (EEG) rhythms were collected and cortical source estimation of delta (<4 Hz) to gamma (>30 Hz) bands with exact Low Resolution Electromagnetic Tomography (eLORETA) was performed. <b>Results:</b> Most LOEU patients had an MCI status at seizure onset (59%). Patients with LOEU-MCI performed significantly worse on measures of global cognition, visuo-spatial abilities, and executive functions compared to NE-MCI patients (<i>p</i> < 0.05). Regarding MCI subtypes, multiple-domain MCI was 3-fold more frequent in LOEU-MCI than in NE-MCI patients (OR 3.14, 95%CI 0.93-10.58, <i>p</i> = 0.06). CSF Aβ42 levels were lower in the LOEU-MCI compared with the LOEU-CN group. Finally, parietal and occipital sources of alpha (8-12 Hz) rhythms were less active in the LOEU-MCI than in the NE-MCI and CN groups, while the opposite was true for frontal and temporal cortical delta sources. <b>Discussion:</b> MCI status was relatively frequent in LOEU patients, involved multiple cognitive domains, and might have been driven by amyloidosis according to CSF biomarkers. LOEU-MCI status was associated with abnormalities in cortical sources of EEG rhythms related to quiet vigilance. Future longitudinal studies should cross-validate our findings and test the predictive value of CSF and EEG variables.
Feedback Encoding for Efficient Symbolic Control of Dynamical Systems (2006)

The problem of efficiently steering dynamical systems by generating input plans is considered. Plans are considered which consist of finite-length words constructed on an alphabet of input symbols, which could be, e.g., transmitted through a limited capacity channel to a remote system, where they can be decoded in suitable control actions. Efficiency is considered in terms of the computational complexity of plans, and in terms of their description length (in number of bits). We show that, by suitable choice of the control encoding, finite plans can be efficiently built for a wide class of dynamical systems, computing arbitrarily close approximations of a desired equilibrium in polynomial time. The paper also investigates how the efficiency of planning is affected by the choice of inputs, and provides some results as to optimal performance in terms of accuracy and range.
1D algorithm for automatic fringe spacing measurement in a straight equispaced parallel fringe pattern (2000)

Wavelength measurement is a critical topic in many applications. Stationary interferometers, such as Fizeau and Murty, can be successfully used, considering the proportionality between the wavelength and the fringe spacing in the interference pattern.In this work we present a 1D algorithm for the calculation of the fringe spacing and error sources. The final accuracy that can be achieved is also assessed. The experimental data are taken from fringe pattern recorded with a Murty interferometer.
A theoretical study on using a fictional mirror to simplify the behavior of a volume Bragg grating in an optical cavity (2016)

Abstract A fictional mirror was proposed to describe the reflective behaviors of a volume Bragg grating (VBG) in an optical cavity. When a finite beam interacts with a VBG, the analytical forms of the location and the radius of curvature of the fictional mirror are derived. In addition, the longitudinal mode spacing of an optical cavity using a VBG as the cavity mirror is investigated theoretically and experimentally.
Isothermal crystallization and time-temperature-transformation diagram of the organic semiconductor 5,11-bis(triethylsilylethynyl)anthradithiophene (2021)

The time-temperature-transformation diagram describing crystallization of the semiconducting molecule TES-ADT from its melt was constructed and found to correlate with the thin-film micro/nanostructure and electronic performance.
Noise Improvement for a High NA MO System (1999)

A feasibility study of a magneto-optical(MO) disk for an NA 0.85 system is presented. The disk noise level in this system was relatively large compared to the conventional NA 0.55 system at the recording density corresponding to this spot size. Two methods were introduced for the improvement. One was the optimization of the groove structure, and the other was the reduction of the metal surface roughness. The former was found to be the typical noise source for optics for a narrower track pitch disk. A UV ashing apparatus was utilized for reduction of the noise. The latter noise source was characteristic for the surface MO recording, and the etching process was found effective for the improvement. By using both these methods, the noise level was drastically decreased, achieving high areal density of 7 Gb/inch2.
Clostridium thermoaceticumforms methanol from carbon monoxide in the presence of viologen dyes (1987)

Whole cells of Clostridium thermoaceticum, crude extracts of such cells as well as the supernatant of 100 000 × g centrifugations catalyse the reduction of carbon monoxide to methanol in the presence of viologens or cobalt sepulchrate. Without such a mediator methanol could not be detected. The reaction shows a marked optimum at pH 5. The incubation of [5-14C]methyltetrahydrofolate led only to the formation of 14C-labeled ethanol; the radioactivity in methanol was negligible. The reaction seems to be catalysed by carbon monoxide dehydrogenase.
Finite Element Model Updating Using the Separable Shadow Hybrid Monte Carlo Technique (2014)

The use of Bayesian techniques in Finite Element Model (FEM) updating has recently increased. These techniques have the ability to quantify and characterize the uncertainties of dynamic structures. In order to update a FEM, the Bayesian formulation requires the evaluation of the posterior distribution function. For large systems, this functions is either difficult (or not available) to solve in an analytical way. In such cases using sampling techniques can provide good approximations of the Bayesian posterior distribution function. The Hybrid Monte Carlo (HMC) method is a powerful sampling method for solving higher-dimensional complex problems. The HMC uses the molecular dynamics (MD) as a global Monte Carlo (MC) move to reach areas of high probability. However, the acceptance rate of HMC is sensitive to the system size as well as the time step used to evaluate MD trajectory. To overcome this, we propose the use of the Separable Shadow Hybrid Monte Carlo (S2HMC) method. This method generates samples from a separable shadow Hamiltonian. The accuracy and the efficiency of this sampling method is tested on the updating of a GARTEUR SM-AG19 structure.
The Risk of Blood-Borne Viral Infection due to Syringe Re-Use (2012)

In the fall of 2008, light was shed on the practice of syringe re-use occurring in western Canada (Government of Alberta, 2009). In this situation, syringes had been re-used between patients to administer sedating medication through patient intravenous (IV) lines (Government of Alberta, 2009). Later it was reported that other incidents of syringe re-use had occurred in Canada (CBC News-Edmonton, 2008a;CBC News-Edmonton, 2008b). The question arose of whether this practice may have resulted in the transmission of bloodborne pathogens to patients and, if so, how many and with what level of risk. To answer this question, a retrospective study involving approximately 1,400 patients was undertaken (Government of Alberta, 2009). However, questions were also raised as to whether estimates based on modeling scenarios could provide information to guide decisions on the need for look-backs.
Inside Cover: Spiked Gold Beads as Substrates for Single‐Particle SERS (ChemPhysChem 10/2012) (2012)

R. A. Alvarez-Puebla, L. M. Liz-Marzán et al. describe a new type of spiked gold nanoparticle where the size of the core is gradually increased, so that antenna effects contribute to large SERS enhancement factors when engineered into thin films. This is demonstrated on p. 2561 ff. through ultrasensitive analysis of benzenethiol.