gebhart/patrepeval huggingface dataset:
The role of feature density in determining V1 BOLD fMRI sensitivity to spatial phase structure (2004)

Recent fMRI studies in several labs have produced mixed results in measuring the response of V1 to manipulations of global phase coherence in natural images. We have performed a series of experiments that separately examine the role of feature density and spatial frequency in determining V1 BOLD fMRI sensitivity to the phase structure of images. Stimuli were formed in two different spatial frequency bands by placing randomly oriented Gabor patches at three different densities in images; each of these coherent images was contrasted against its phase-scrambled counterpart, equivalent to band-pass noise. A computational model was built to predict the spatial distribution of neural activity and resulting BOLD fMRI response. Modeled neural activity was compared against neural activity inferred from psychophysical measurements of contrast detection and discrimination thresholds; both indicated higher local activity for stimuli with phase coherence. The principle finding is that BOLD fMRI response, when averaged across large regions of interest, is lower when neural activity is sparse. This is the case even when the low-density coherent images have lower detection or discrimination thresholds (i.e. stronger local neural activity), demonstrating that V1 BOLD fMRI results can be misleading when spatial distribution of image features is not taken into account. Both measured and modeled BOLD fMRI responses also produce the following results: 1) sensitivity to phase coherence depends on spatial frequency; 2) population activity is frequently mixed (some voxels showing preference for coherent images; some responding more strongly to scrambled images). Therefore, careful analysis of individual voxel responses (rather than ROI averages) is required for accurate application of BOLD imaging to studies of spatial vision. This work also illustrates that local phase manipulations, rather than global phase manipulations, are more appropriate for the study of V1 responses. NSF/IGERT DGE 9870633, University of Minnesota Graduate School Doctoral Dissertation Fellowship, R01 EB00331, P41 RR08079, the MIND Institute, and the WM KECK Foundation
Proceedings of the 2015 New Security Paradigms Workshop (2015)

To solve the long-standing problems users have in creating and remembering text passwords, a wide variety of alternative authentication schemes have been proposed. Some of these schemes outperform others by various metrics in various contexts. However, ...
Research Progress on Velocity Model of Iron Release in Water Supply Pipe (2012)

The paper gives an overview on velocity models of iron release in water supply pipe at home and abroad, which incorporate empirical statistical models and dynamic models. Meanwhile, the characters of each iron release model are summarized. At last, the author analyzes the frequency of all parameters used in models mentioned in paper and puts forward the developing orientation on velocity models of iron release. The author also concludes that the establishment of velocity models of iron release is conducive to getting command of iron release in water distribution systems and guaranteeing the safety of potable water in drinking water pipe.
High quality de novo sequencing and assembly of the Saccharomyces arboricolus genome (2013)

We suggest that the genome of S. arboricolus will be useful in future comparative genomics analysis of the Saccharomyces sensu stricto yeasts.
Synthesis of [3H]-illudin S, [3H]-acylfulvene, [3H] & [14C]-hydroxymethylacylfulvene (MGI 114) (1998)

Tritiated derivatives of the toxic sesquiterpene illudin S (1) have been prepared by fermentation of Omphalotus illudens in the presence of [3H]-sodium acetate. [3H]-illudin S was converted to antitumour [3H]-acylfulvene (4) by treatment with dilute sulfuric acid. Antitumor [14C]-hydroxymethylacylfulvene (5) was best prepared by reacting acylfulvene with [14C]-paraformaldehyde in dilute sulfuric acid. © 1998 John Wiley & Sons, Ltd.
Towards a vision-based targeting system for counter unmanned aerial systems (CUAS) (2017)

Unmanned aerial vehicles (UAVs) are rapidly increasing in popularity. Despite attempts at regulation, stopping small, Class 1 (typically hobby-grade) UAVs from entering protected or sensitive airspace is an unsolved problem. Many companies and researchers offer a piece of a solution, but as of this writing, there is no publicly available, feasible, end-to-end solution. Ultimately, what is needed is a sensor-based system that autonomously detects, tracks, and neutralizes/disables an incoming UAV. However, such a system is currently not available, so as development toward that goal continues, a temporary solution is required. Augmenting the skill, dexterity, and processing power of human pilots with inexpensive cameras and computer vision algorithms can offer such a solution. The foundations of a framework for a system that uses computer vision to target and ultimately destroy a target in mid-air is introduced. The proposed solution utilizes a light-weight, inexpensive UAV with an on-board camera. The detection and tracking is performed in real-time on a companion computer mounted to the frame of the vehicle, with ROS as the primary communication infrastructure. Initial simulations provide insight into the feasibility of using computer vision with a monocular camera to offer reliable assistance to the pilot.
A 800 MB/s 72 Mb SLDRAM with digitally-calibrated DLL (2003)

This 72 Mb synchronous-link DRAM (SLDRAM) is a proof-of-concept vehicle for next-generation memory. SLDRAM is a packet-protocol-based memory that employs source-synchronous busses with push-pull I/O for signaling integrity. SLDRAM devices are calibrated on power-up by the memory controller so individual memory devices do not have to meet tight timing specifications and compensate interconnect and loading variations.
Synthesis and properties of acrylate‐acrylic acid‐acrylate triblock copolymers with gemini structure by RAFT polymerization (2015)

ABSTRACT A class of gemini structure block copolymers with a trithiocarbonate ester spacer group had been synthesized with S, S′‐bis (R, R′‐dimethylacetic acid) trithiocarbonate as reversible addition fragmentation chain transfer agents and acrylic acid as the second monomer. These triblock copolymers were characterized by 1 H NMR spectroscopy, gel permeation chromatography in terms of their compositions, molecular weights and behaviour at the air–water interface. The results showed that the weight‐average molecular weight was larger than theoretical molecular as the acrylate side chain increased. The polymer neutralized by sodium hydroxide solution had low critical micelle concentration which was &lt;10 −2 mol L −1 in water. TEM and DLS showed that it formed a special micelle structure with large pore structure which might lead to low surface tension and critical micelle concentration in water. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016 , 133 , 43017.
Figure S2 from Response to Immune Checkpoint Inhibition in Two Patients with Alveolar Soft-Part Sarcoma (2023)

&lt;p&gt;Immunohistochemistry in MLH1, MSH2, MSH6 and PMS2 showed intact IHC expression in Patient 1 (magnification: 200x).&lt;/p&gt;
WE-D-207-00: CT Lung Cancer Screening and the Medical Physicist: Moving Forward (2015)

In the United States, Lung Cancer is responsible for more cancer deaths than the next four cancers combined. In addition, the 5 year survival rate for lung cancer patients has not improved over the past 40 to 50 years. To combat this deadly disease, in 2002 the National Cancer Institute launched a very large Randomized Control Trial called the National Lung Screening Trial (NLST). This trial would randomize subjects who had substantial risk of lung cancer (due to age and smoking history) into either a Chest X-ray arm or a low dose CT arm. In November 2010, the National Cancer Institute announced that the NLST had demonstrated 20% fewer lung cancer deaths among those who were screened with low-dose CT than with chest X-ray. In December 2013, the US Preventive Services Task Force recommended the use of Lung Cancer Screening using low dose CT and a little over a year later (Feb. 2015), CMS announced that Medicare would also cover Lung Cancer Screening using low dose CT. Thus private and public insurers are required to provide Lung Cancer Screening programs using CT to the appropriate population(s). The purpose of this Symposium is to inform medical physicists and prepare them to support the implementation of Lung Screening programs. This Symposium will focus on the clinical aspects of lung cancer screening, requirements of a screening registry for systematically capturing and tracking screening patients and results (such as required Medicare data elements) as well as the role of the medical physicist in screening programs, including the development of low dose CT screening protocols. Learning Objectives: 1. To understand the clinical basis and clinical components of a lung cancer screening program, including eligibility criteria and other requirements. 2. To understand the data collection requirements, workflow, and informatics infrastructure needed to support the tracking and reporting components of a screening program. 3. To understand the role of the medical physicist in implementing Lung Cancer Screening protocols for CT, including utilizing resources such as the AAPM Protocols and the ACR Designated Lung Screening Center program. UCLA Department of Radiology has an Institutional research agreement with Siemens Healthcare; Dr. McNitt-Gray has been a recipient of Research Support from Siemens Healthcare in the past. Dr. Aberle has been a Member of Advisory Boards for the LUNGevity Foundation (2011-present) and Siemens Medical Solutions. (2013).
A Generic Multipurpose recommender System for Contextual Recommendations (2007)

Identifying correlations between context data, user behavior, and semantic information can lead to new services that are able to adapt to different situations. This "personalization" process can be based on recommendations on content. To better support service developers in focusing mainly on the creation of their service logic, these recommendations should be provided by a generic multipurpose recommender. Therefore, this paper proposes a generic framework that delivers "contextual recommendations" that are based on the combination of previously gathered user feedback data (i.e. ratings and clickstream history), context data, and ontology-based content categorization schemes. This paper provides a detailed overview of the specification, a short description of a possible usage scenario, and a discussion of the results
Elastin repeat peptides as chemoattractants for bovine aortic endothelial cells (1989)

Cultured bovine aortic endothelial cells migrate toward a concentration gradient of repeating elastin peptides, specifically the repeating nonamers Gly-Phe-Gly-Val-Gly-Ala-Gly-Val-Pro and Gly-Leu-Gly-Val-Gly-Ala-Gly-Val-Pro and the repeating hexamer Val-Gly-Val-Ala-Pro-Gly. Dose-response experiments demonstrate that the peak of activity occurs at 8 x 10(-8) M for the nonapeptides and 1 x 10(-8) M for the hexapeptide. Checkerboard assays establish that the movement is chemotaxis and not chemokinesis. Because of the concentration difference in the responsiveness between the nonapeptide and the hexapeptide, the cells can differentiate between the two types of repeats. The positive control for the chemotaxis studies was fibronectin.
Characterization of Natural Suppressor Cells in Human Bone Marrow (1998)

Natural suppressor (NS) cells, which exert nonspecific suppressive activity in an unprimed manner, have been found in mouse, rabbit and monkey bone marrow (BM). In the present study, we characterize NS cells in human BM. NS activity was found in a fraction of low density (1.055-1.065 g/ml) BM cells that had been depleted of T cells, B cells, and monocytes. The NS activity was significantly decreased by the depletion of CD34+ or CD33+ cells but not CD56+ cells. The NS activity was indeed detected in isolated CD34+ cells and further enriched in CD34+CD33+ cells. Hematopoietic progenitor cells committed to the myeloid lineage were also enriched in the CD34+CD33+ cells, which significantly correlated to the NS activity. From these findings, it is strongly suggested that NS activity in human BM is exerted by the myeloid hematopoietic progenitors. Since cell-to-cell contact was not necessary for the action, NS cells seemed to secrete soluble mediator(s). Transforming growth factor-beta 1 and leukemia inhibitory factor were, however, not the candidates, based on experiments using neutralizing antibodies.
The Biosynthesis of Chlorobium Chlorophylls-660. The Production of Magnesium Protoporphyrin Monomethyl Ester, Bacteriochlorophyll, and Chlorobium Pheoporphyrins by Chlorobium thiosulfatophilum-660* (1967)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Biosynthesis of Chlorobium Chlorophylls-660. The Production of Magnesium Protoporphyrin Monomethyl Ester, Bacteriochlorophyll, and Chlorobium Pheoporphyrins by Chlorobium thiosulfatophilum-660*William R. Richards and Henry RapoportCite this: Biochemistry 1967, 6, 12, 3830–3840Publication Date (Print):December 1, 1967Publication History Published online1 May 2002Published inissue 1 December 1967https://pubs.acs.org/doi/10.1021/bi00864a029https://doi.org/10.1021/bi00864a029research-articleACS PublicationsRequest reuse permissionsArticle Views63Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Design and fabrication of high-efficiency beam splitters and beam deflectors for integrated planar micro-optic systems (1993)

High-frequency gratings with rectangular-groove profiles are used to generate high-efficiency beam splitters and beam deflectors. The effects of the grating design parameters, i.e., period, groove depth, duty cycle, number of phase levels, and polarization state (TE and TM) of the incoming signal, are considered. The case of the binary beam splitter grating is analyzed by using rigorous electromagnetic grating analysis. Fabrication techniques are presented in which three different lithographic techniques are considered (optical contact, deep-UV stepper reduction, and electron-beam direct write). Experimental results of 97% efficiency for the beam splitter grating and up to 80% for the beam deflector grating are reported.
Enhancing Nearest Neighbor Based Entropy Estimator for High Dimensional Distributions via Bootstrapping Local Ellipsoid (2020)

An ellipsoid-based, improved kNN entropy estimator based on random samples of distribution for high dimensionality is developed. We argue that the inaccuracy of the classical kNN estimator in high dimensional spaces results from the local uniformity assumption and the proposed method mitigates the local uniformity assumption by two crucial extensions, a local ellipsoid-based volume correction and a correction acceptance testing procedure. Relevant theoretical contributions are provided and several experiments from simple to complicated cases have shown that the proposed estimator can effectively reduce the bias especially in high dimensionalities, outperforming current state of the art alternative estimators.
Anaesthesia of gemsbok (Oryx gazella) with a combination of A3080, medetomidine and ketamine (2001)

An effective anaesthesia protocol was developed for adult free-ranging gemsbok (Oryx gazella) using a combination of A3080, medetomidine and ketamine. A short induction time; good muscle relaxation, adequate oxygenation and stable heart rate and respiration rate characterised this anaesthetic regime. Equal doses of A3080 and medetomidine (22-45 microg/kg) plus 200 mg of ketamine were administered to each animal. The anaesthesia was rapidly and completely reversed by intramuscular naltrexone at a dose of X = 0.9 +/- 0.2 mg/kg and atipamezole at a dose X +/- 90 +/- 20 microg/kg. No mortality or morbidity occurred with this protocol.
Five-Year Metabolic, Functional, and Safety Results of Patients With Type 1 Diabetes Transplanted With Allogenic Islets Within the Swiss-French GRAGIL Network (2015)

In a large cohort with a 5-year follow-up and in a multicenter network setting, islet transplantation was safe and efficient in restoring good and lasting glycemic control and preventing severe hypoglycemia in patients with type 1 diabetes.
Signal Processing for Polarization Multiplexed Coherent WDM Transmission (2010)

A blind format-independent polarization demultiplexing technique using independent component analysis and nonlinearity compensation for polarization-division multiplexing WDM transmission will be presented. Article not available.
Characterization of an Estrogen-Binding Protein in the YeastCandida albicans* (1989)

An estrogen-binding protein (EBP) has been identified and characterized in the cytosol of the pathogenic yeast Candida albicans. Binding of [3H]estradiol was found to be optimal at pH 7.4 in the presence of 0.3 M KCl and was linearly related to protein concentration. Binding was very rapid, reaching maximal levels in about 30 min, and was reversible with a dissociation rate constant of 13.2 +/- 1.7 x 10(-4) sec-1. EBP binding was destroyed by treatment with proteolytic enzymes and by high temperatures. Scatchard analysis of the [3H]estradiol equilibrium binding data of C. albicans (strain stn-1) yielded an apparent dissociation constant of 12.3 +/- 2.1 nM and a maximal binding capacity of 753 +/- 145 fmol/mg protein. Binding competition experiments showed very high specificity and stereoselectivity of EBP, demonstrating the following order of potency in displacing [3H]estradiol: 17 beta-estradiol greater than estrone greater than estriol greater than 17 alpha-estradiol. Negligible competitive potency was found for other mammalian steroid hormones, diethylstilbestrol, tamoxifen, or fungal hormones. The abundance of EBP was 4- to 10-fold higher during the early logarithmic growth phase of yeast cells than during the stationary phase. The molecular size of EBP, measured by Sephacryl S-200 gel exclusion chromatography, yielded a Stokes radius of approximately 29 A. Sucrose density gradient sedimentation showed a sedimentation coefficient (S2020,W) of 4, with no ionic dependent aggregation of the [3H]estradiol-EBP complex. The apparent mol wt of the EBP is approximately 46,000, with an axial ratio of 1, indicating the symmetrical shape of the molecule. In summary, in addition to the previously described corticosterone-binding protein, a separate high affinity, stereospecific, estrogen-selective binder has been demonstrated in the cytosol of C. albicans.
Better Document-level Sentiment Analysis from RST Discourse Parsing (2015)

Discourse structure is the hidden link between surface features and document-level properties, such as sentiment polarity. We show that the discourse analyses produced by Rhetorical Structure Theory (RST) parsers can improve document-level sentiment analysis, via composition of local information up the discourse tree. First, we show that reweighting discourse units according to their position in a dependency representation of the rhetorical structure can yield substantial improvements on lexicon-based sentiment analysis. Next, we present a recursive neural network over the RST structure, which offers significant improvements over classificationbased methods.
Volatile Aromatic Anesthetics Variably Impact Human γ-Aminobutyric Acid Type A Receptor Function (2007)

These findings suggest that GABA(A) receptors contribute variably to the behavioral actions of volatile anesthetics and imply that the molecular determinants of anesthetic action on NMDA and GABA(A) receptors are distinctly different.
기부노력에 영향을 미치는 요인에 관한 연구 :행복감과 사회적 신뢰 및 두 요인의 상호작용효과 분석 (2012)

기부행동 영향 요인에 대한 탐색은 민간 영역에서의 자원 확보를 통한 사회적 안정성 제고 측면에서 매우 중요한 과제이다. 다양한 요인에 대한 탐색이 있어 왔으나, 최근 행복과 신뢰에 대한 관심이 크다. 이러한 배경을 반영하여 본 연구는 개인의 ‘행복감’과 사회에 대한 ‘신뢰’, 그리고 이들간의 상호작용효과에 초점을 두고 이들 요인이 기부노력과 어떠한 관계에 있는지를 검증해 보고자하였다. 이를 위해 높은 대표성을 지니는 서울 복지패널조사의 2008년 및 2010년 자료를 토대로 기존의 연구들에서 활용되어온 주요 변수들을 통제하면서 분석과정에서 발생할 수 있는 표본선택 편의의 문제를 교정하는데 유용한 헤크만 선택 모형을 이용하여 검증하였다. 분석 결과, 사회적 신뢰는 부적인 방향에서, 행복감은 정적인 방향에서, 행복감과 사회적 신뢰의 상호작용효과는 정적인 방향에서 유의한 것으로 나타났다. 그리고 사회적 신뢰보다는 개인의 행복감(+)이 기부노력에 보다 큰 영향력을 갖는 것으로 나타났다. 이와 같은 결과가 갖는 의미에 대해 논의하고 후속연구의 방향을 제시하였다.
Cross-layer multichannel aggregation for future WLAN systems (2010)

With the increase in the channel bandwidth to satisfy data rate requirements, the saturation of unlicensed bands quickly becomes a source of difficulty. The collisions that result from the ineluctable frequency reuse will then seriously hinder MAC layer performance. In this paper, we propose a new cross-layer aggregation scheme that increases throughput as a result of compromise between robustness to collisions and channel diversity exploitation in a WLAN multichannel context, like 802.11ac. This new scheme is compared with the 802.11n aggregation model, extended to more concatenated channels, so as to compass the improvements perceived by the every day user.
Controlling Incoming Macrophages to Implants: Responsiveness of Macrophages to Gelatin Micropatterns under M1/M2 Phenotype Defining Biochemical Stimulations (2017)

Adverse immune reactions to implanted devices can seriously hamper the efficacy of implants. Monocyte derived macrophages play a crucial role in both initiation and resolution of the inflammatory response toward foreign bodies. As the surface microtopography is shown to exert significant effects on cell phenotype, it is hypothesized that the presence of micropatterns on implant/medical device surfaces can attenuate the immune response. To this end, enzymatically crosslinked micropatterned gelatin films of varying groove widths (2, 5, 10, 20, and 40 µm) are tested for their effect on incoming monocyte behavior. In order to distinguish the effect of cytokine microenvironment on pattern presence, monocytes are seeded on micropatterned films in normal culture medium or M1/M2 inducing media and their morphology and cytokine secretions are observed for 6 d. The presence of the patterns induces microenvironment‐specific changes on the secretions of the attached cells and also on their size. IL‐1ß, IL‐4, IL‐12, TNF‐α, and CCL‐18 secretions are significantly affected particularly in M1 induction media by pattern presence. It is demonstrated for the first time that micropatterned surfaces can be used to control the initial attachment and cytokine secretion of incoming macrophages if they are linked with a polarization inducing cytokine microenvironment.