gebhart/patrepeval huggingface dataset:
Design of piece-wise maps for spread spectrum communication using genetic programming (2002)

The design of piece-wise maps for code generation in Direct Sequence Spread Spectrum (DS/SS) systems is a challenging problem. We propose the use of genetic programming (GP) to design maps that can be used for the generation of codes in DS/SS systems. Using appropriate functional operators, we use GP to construct exploitable maps of the interval [0,1]. The search is directed based on a multi-objective genetic programming framework with the two criteria being the average auto-correlation and cross-correlation performance of the maps.
Malaria Infection and Gametocyte Carriage Rates in Preparation for Transmission Blocking Vaccine Trials in Bancoumana, Mali (2017)

The epidemiological characterization of transmission reservoirs is a critical step in preparation for interventional trials for malaria elimination/eradication. Using cluster sampling and households/compounds as units of sampling, we recruited and followed monthly, from June 2011 to June 2012, 250 volunteers 3 months to 50 years of age in Bancoumana, Mali. In July 2012, only participants 5-35 years of age (<i>N</i> = 121) were reenrolled and followed for an additional year. Malaria infection prevalence was highest in October in both 2011 (21.5%, 50/233) and 2012 (38.2%, 26/68). During both years, malaria infection prevalence was highest in children 5-14 years of age (<i>P</i> = 0.01 and <i>P</i> = 0.02, respectively). The gametocyte carriage prevalence was highest in November 2011 (7.6%, 17/225) and in October 2012 (16.2%, 11/68). Gametocyte carriage rates by age did not significantly differ in 2011 and 2012. In Bancoumana, the asexual and sexual parasite carriage rates are relatively high and highly seasonal. Seasonal variation and age differences in parasite and gametocyte carriage provide essential knowledge for the design of transmission blocking assay and vaccine studies in the field.
Implementation of orthogonal wavelet transforms and their applications (2002)

In this paper the efficient implementation of different types of orthogonal wavelet transforms with respect to practical applications is discussed. Orthogonal single-wavelet transforms being based on one scaling function and one wavelet function are used for denosing of signals. Orthogonal multiwavelets are based on several scaling functions and several wavelets. Since they allow properties like regularity, orthogonality and symmetry being impossible in the single-wavelet case, multiwavelets are well suited bases for image compression applications. With respect to an efficient implementation of these orthogonal wavelet transforms approximating the exact rotation angles of the corresponding orthogonal wavelet lattice filters by using very few CORDIC-based elementary rotations reduces the number of shift and add operations significantly. The performance of the resulting, computationally cheap, approximated wavelet transforms with respect to practical applications is discussed in this paper.
Efficient parallel algorithms and VLSI architectures for manipulator Jacobian computation (1989)

The real-time computation of the Jacobian that relates the manipulator joint velocities to the linear and angular velocities of the manipulator end-effector is pursued. Since the Jacobian can be expressed in the form of a first-order linear recurrence, the time lower bound for computing the Jacobian can be proved to be of order O(N) on uniprocessor computers and of order O(log/sub 2/ N) on both single-instruction-stream-multiple-data-stream (SIMD) and VLSI pipelined parallel processors, where N is the number of links of the manipulator. To achieve the lower bound, the authors developed a generalized-k method for uniprocessor computers, a parallel forward and backward recursive doubling algorithm (PFABRD) for SIMD computers, and a parallel systolic architecture for VLSI pipelines. All the methods are capable of computing the Jacobian at any desired reference coordinate frame k from the base coordinate frame to the end-effector coordinate frame. The computational effort in terms of floating-point operations is minimal when k is in the range (4,N-3) for the generalized-k method, and k=(N+1)/2 for both the PFABRD algorithm and the parallel pipeline.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Correction to Stochastic On-Chip Detection of Subpicomolar Concentrations of Silver Nanoparticles (2016)

ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to Stochastic On-Chip Detection of Subpicomolar Concentrations of Silver NanoparticlesKay J. Krause, Alexey Yakushenko, and Bernhard Wolfrum*Cite this: Anal. Chem. 2016, 88, 12, 6627Publication Date (Web):June 9, 2016Publication History Published online9 June 2016Published inissue 21 June 2016https://pubs.acs.org/doi/10.1021/acs.analchem.6b01755https://doi.org/10.1021/acs.analchem.6b01755correctionACS PublicationsCopyright © 2016 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views463Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (114 KB) Get e-Alertsclose Get e-Alerts
A Bayesian approach to problems in stochastic estimation and control (1964)

In this paper, a general class of stochastic estimation and control problems is formulated from the Bayesian Decision-Theoretic viewpoint. A discussion as to how these problems can be solved step by step in principle and practice from this approach is presented. As a specific example, the closed form Wiener-Kalman solution for linear estimation in Gaussian noise is derived. The purpose of the paper is to show that the Bayesian approach provides; 1) a general unifying framework within which to pursue further researches in stochastic estimation and control problems, and 2) the necessary computations and difficulties that must be overcome for these problems. An example of a nonlinear, non-Gaussian estimation problem is also solved.
Collaborative Process Development using Semantic MediaWiki. (2009)

Often organizational processes are rather informal, subject to frequent changes, and involve roles with unclear responsibilities. Nevertheless it can be beneficial for efficient organizational knowledge management to document and communicate such processes. In this context, current state-of-the-art methods and tools for process engineering do not provide the most appropriate instruments. In this paper we address this issue by combining traditional process engineering techniques with a collaborative, wiki-based approach. As a result we present an extension to Semantic MediaWiki featuring collaborative creation of a process description and the automated generation of its structured, graphical representation.
Therapeutic interventions in children and adolescents with patellar tendon related pain: a systematic review (2018)

There is weak evidence to support the use of dextrose injection with local anaesthetic and no evidence to support the use of specific types of exercises to treat children/adolescents with OSD/patellar tendinopathy. Until further evidence arises, clinicians should include load modification and advise on a return to sport based on symptoms.
Dendrimers: Solutions For Catalyst Separation and Recycling–A Review † Dedicated to the memory of Dr. José Antonio Delgado Oyagüe. (2008)

Dendrimers provide new and practical solutions to the complex problem of catalyst separation from the product stream. Dendrimers functionalized with active metal complexes are themselves soluble, nanosized catalysts that are capable of combining the high activity and selectivity of classical homogeneous catalysts with the enhanced separation capabilities added by the macromolecule. This report reviews the recovery and recycling of metallodendrimer catalysts by different separation techniques, such as nanofiltration, precipitation, or catalyst immobilization on solid supports, or by the use of appropriate solvent media, as illustrated by representative examples.
Pharmacology of rosemary (Rosmarinus officinalis Linn.) and its therapeutic potentials. (1999)

The use of plants is as old as the mankind. Natural products are cheap and claimed to be safe. They are also suitable raw material for production of new synthetic agents. Rosemary (Rosmarinus officinalis Linn.) is a common household plant grown in many parts of the world. It is used for flavouring food, a beverage drink, as well as in cosmetics; in folk.medicine it is used as an antispasmodic in renal colic and dysmenorrhoea, in relieving respiratory disorders and to stimulate growth of hair. Extract of rosemary relaxes smooth muscles of trachea and intestine, and has choleretic, hepatoprotective and antitumerogenic activity. The most important constituents of rosemary are caffeic acid and its derivatives such as rosmarinic acid. These compounds have antioxidant effect. The phenolic compound, rosmarinic acid, obtains one of its phenolic rings from phenylalanine via caffeic acid and the other from tyrosine via dihydroxyphenyl-lactic acid. Relatively large-scale production of rosmarinic acid can be obtained from the cell culture of Coleus blumei Benth when supplied exogenously with phenylalanine and tyrosine. Rosmarinic acid is well absorbed from gastrointestinal tract and from the skin. It increases the production of prostaglandin E2 and reduces the production of leukotriene B4 in human polymorphonuclear leucocytes, and inhibits the complement system. It is concluded that rosemary and its constituents especially caffeic acid derivatives such as rosmarinic acid have a therapeutic potential in treatment or prevention of bronchial asthma, spasmogenic disorders, peptic ulcer, inflammatory diseases, hepatotoxicity, atherosclerosis, ischaemic heart disease, cataract, cancer and poor sperm motility.
Resonant cavity enhanced InP/InGaAs photodiode on Si using epitaxial liftoff (1994)

Epitaxial liftoff (ELO) is used in the fabrication of an InP/InGaAs resonant cavity photodetector on Si. External mirrors were employed with the bottom mirror consisting of an intermediate gold layer between the Si and ELO InP film. A dielectric stack of Si/SiO2 was used as the top mirror instead of a semitransparent metallic mirror to increase the quantum efficiency further. An external quantum efficiency of 0.57 in the spectral region of 1.55 μm was obtained for a 2500-Å-thick InGaAs absorbing layer. This is four times larger than the predicted value for a conventional pin photodiode with the same absorbing layer thickness. The spectral response showed wavelength selectivity. A full width at half-maximum of 150 Å is obtained with the top mirror reflectivity matched for optimum quantum efficiency. Further increase in the top mirror reflectivity improved spectral selectivity but at the expense of reduced quantum efficiency.
Bioengineered stem cells as an alternative for islet cell transplantation (2015)

Type 1 diabetes is an autoimmune and increasingly prevalent condition caused by immunological destruction of beta cells. Insulin remains the mainstay of therapy. Endeavours in islet transplantation have clearly demonstrated that type 1 diabetes is treatable by cellular replacement. Many challenges remain with this approach. The opportunity to use bioengineered embryonic or adult pluripotential stem cells, or islets derived from porcine xenograft sources could address future demands, but are still associated with considerable challenges. This detailed review outlines current progress in clinical islet transplantation, and places this in perspective for the remarkable scientific advances now occurring in stem cell and regenerative medicine approaches in the treatment of future curative treatment of diabetes.
Structure-function relationship of bacterial prolipoprotein diacylglyceryl transferase: functionally significant conserved regions (1995)

The structure-function relationship of bacterial prolipoprotein diacylgyceryl transferase (LGT) Has been investigated by a comparison of the primary structures of this enzyme in phylogenetically distant bacterial species, analysis of the sequences of mutant enzymes, and specific chemical modification of the Escherichia coli enzyme. A clone containing the gene for LGT, lgt, of the gram-positive species Staphylococcus aureus was isolated by complementation of the temperature-sensitive lgt mutant of E. coli (strain SK634) defective in LGT activity. In vivo and in vitro assays for prolipoprotein diacylglyceryl modification activity indicated that the complementing clone restored the prolipoprotein modification activity in the mutant strain. Sequence determination of the insert DNA revealed an open reading frame of 837 bp encoding a protein of 279 amino acids with a calculated molecular mass of 31.6 kDa. S. aureus LGT showed 24% identity and 47% similarity with E. coli, Salmonella typhimurium, and Haemophilus influenzae LGT.S. aureus LGT, while 12 amino acids shorter than the E. coli enzyme, had a hydropathic profile and a predicted pI (10.4) similar to those of the E. coli enzyme. Multiple sequence alignment among E. coli, S. typhimurium, H. influenzae, and S. aureus LGT proteins revealed regions of highly conserved amino acid sequences throughout the molecule. Three independent lgt mutant alleles from E. coli SK634, SK635, and SK636 and one lgt allele from S. typhimurium SE5221, all defective in LGT activity at the nonpermissive temperature, were cloned by PCR and sequenced. The mutant alleles were found to contain a single base alteration resulting in the substitution of a conserved amino acid. The longest set of identical amino acids without any gap was H-103-GGLIG-108 in LGT from these four microorganisms. In E. coli lgt mutant SK634, Gly-104 in this region was mutated to Ser, and the mutant organism was temperature sensitive in growth and exhibited low LGT activity in vitro. Diethylpyrocarbonate inactivated the E. coli LGT with a second-order rate constant of 18.6 M-1S-1, and the inactivation of LGT activity was reversed by hydroxylamine at pH 7. The inactivation kinetics were consistent with the modification of a single residue, His or Tyr, essential for LGT activity.
High-resolution CT analysis of facial struts in trauma: 1. Normal anatomy (1983)

The recent availability of high-spatial-resolution thin-section computed tomography (CT), capable of accurately depicting the thin body septa of the facial skeleton, has expanded the role that diagnostic radiology can play in the evaluation of the patient with facial trauma. A detailed knowledge of the normal CT anatomy of the face, however, is essential to optimally utilize this modality. The normal anatomy of the face was investigated in six cadavers using thin-section (1.5 mm) high-resolution CT. A systematic method of analysis that can facilitate evaluation of the face is presented. The face is conceptualized as three groups of interconnected osseous struts or buttresses that are oriented in the horizontal, sagittal, and coronal planes. Each group of struts is closely related to specific soft-tissue structures that are susceptible to injury. Sequential evaluation of each strut and its associated soft tissue assures a comprehensive evaluation of the face. While both axial and coronal sections are of value in some circumstances, the coronal ones are most helpful in accurately depicting the structures of the face that are most likely to be injured in trauma.
Miniribozymes, small derivatives of the sunY intron, are catalytically active. (1989)

The self-splicing sunY intron from bacteriophage T4 has the smallest conserved core secondary structure of any of the active group I introns. Here we show that several nonconserved regions can be deleted from this intron without complete loss of catalytic activity. The 3' stems P9, P9.1, and P9.2 can be deleted while retaining 5' cleaving activity. Two base-paired stems (P7.1 and P7.2) that are peculiar to the group IA introns can also be deleted; however, the activities of the resulting derivatives depend greatly on the choice of replacement sequences and their lengths. The smallest active derivative is less than 180 nucleotides long. These experiments help to define the minimum structural requirements for catalysis.
Aaltjesschade in gras : een onderschat probleem? (2006)

Schade aan golfbanen en sportvelden wordt in Nederland vaak toegeschreven aan gebrekkige bemesting, schimmelaantasting of vreterij door emelten of andere insecten. Er wordt niet direct gedacht aan schade door aaltjes. In ons land is onderzoek naar schadelijke aaltjes, ofwel nematoden, niet standaard voor de aanleg van golfbanen, gazons of sportvelden. In tegenstelling tot landen met veel golfbanen en sportvelden zoals Engeland en de Verenigde Staten. In grondmonsters uit slecht groeiende plekken van golfbanen werden in deze landen diverse schadelijke aaltjessoorten gevonden
A hierarchical analysis approach for high performance computing and communication applications (2003)

The design, analysis and development of parallel and distributed applications in High Performance Computing and Communication (HPCC) Systems are still very challenging tasks. Therefore, there is a great need for an integrated multilevel analysis methodology to assist in designing and analyzing the performance of both existing and proposed new HPCC systems. Currently, there are no comprehensive analysis methods that address such hierarchical modeling approach for analyzing the end-to-end performance of an application running on an HPCC system. The overall system is partitioned into application level, protocol level and network level. Functions at each level are modeled using queueing networks. The approach enables the designer to study performance for different types of networks and protocols and different design strategies. In this paper we use video-on-demand as an application example to show how our approach can be used to analyze the performance of such an application.
Manufacturability-Aware Design of Standard Cells (2007)

We focus our attention on the layout dependent Across Chip Linewidth Variability (ACLV) of gate-forming poly-silicon patterns as a measure for manufacturability, which is a major contributor of systematic gate-length variation. First, we study the ACLV of standard cell layouts by lithography simulation. Then, we introduce regularity in gate-forming poly-silicon patterns and how it improves the ACLV and also how it incurs area-overhead. According to the investigation, we propose two design guidelines for standard-cell layout that can reduce ACLV with reasonable area overhead. Those guidelines include on-grid fixed-pitch layout with dummy-poly insertion and stretched gate-poly extension. Design experiments assuming a 65 nm process technology indicate that a D-FF designed with the first guideline reduces ACLV by 35% with 14% area overhead and the second guideline reduces ACLV by 75% with 29% area overhead at the best focus condition. Under defocus conditions, both layouts exhibit stable characteristics whereas the variability of conventional layout grows rapidly as the level of defocus increases. Circuit-level lithography simulation over benchmark circuits also supports that the proposed guidelines considerably reduces the amount of gate length variation.
Rapid Plant Identification Using Species- and Group-Specific Primers Targeting Chloroplast DNA (2012)

Plant identification is challenging when no morphologically assignable parts are available. There is a lack of broadly applicable methods for identifying plants in this situation, for example when roots grow in mixture and for decayed or semi-digested plant material. These difficulties have also impeded the progress made in ecological disciplines such as soil- and trophic ecology. Here, a PCR-based approach is presented which allows identifying a variety of plant taxa commonly occurring in Central European agricultural land. Based on the trnT-F cpDNA region, PCR assays were developed to identify two plant families (Poaceae and Apiaceae), the genera Trifolium and Plantago, and nine plant species: Achillea millefolium, Fagopyrum esculentum, Lolium perenne, Lupinus angustifolius, Phaseolus coccineus, Sinapis alba, Taraxacum officinale, Triticum aestivum, and Zea mays. These assays allowed identification of plants based on size-specific amplicons ranging from 116 bp to 381 bp. Their specificity and sensitivity was consistently high, enabling the detection of small amounts of plant DNA, for example, in decaying plant material and in the intestine or faeces of herbivores. To increase the efficacy of identifying plant species from large number of samples, specific primers were combined in multiplex PCRs, allowing screening for multiple species within a single reaction. The molecular assays outlined here will be applicable manifold, such as for root- and leaf litter identification, botanical trace evidence, and the analysis of herbivory.
ANALYSIS OF THE SINGULAR VALUE DECOMPOSITION AS A TOOL FOR PROCESSING MICROARRAY EXPRESSION DATA (2005)

Abstract. We give two informative derivations of a spectral algorithm for clustering and par-titioning a bi-partite graph. In the rst case we begin with a discrete optimization problem that relaxes into a tractable continuous analogue. In the second case we use the power method to derive an iterative interpretation of the algorithm. Both versions reveal a natural approach for re-scaling the edge weights and help to explain the performance of the algorithm in the presence of outliers. Our motivation for this work is in the analysis of microarray data from bioinformatics, and we give some numerical results for a publicly available acute leukemia data set.
Supplementary Figure S3. Treatment profiling of PDX models from B-Cell Lymphoma Patient-Derived Xenograft Models Enable Drug Discovery and Are a Platform for Personalized Therapy (2023)

&lt;p&gt;Freshly isolated lymphoma cells from PT2-BL-G6 and G7 PDXs. Cell viability was tested by CellTiter-Glo luminescent cell viability assay after 48-hour incubation with the indicated drug treatment. The in vitro drug and dose information for IBN and ABT-199 are listed in Supplementary Table S1. IBN, ibrutinib; PT, patient; BL, Burkitt's lymphoma.&lt;/p&gt;