gebhart/patrepeval huggingface dataset:
Prenatal Stress Alters Early Neurobehavior, Stress Reactivity and Learning in Non-human Primates: A Brief Review (2001)

In this paper we review three prospective longitudinal studies from our laboratory examining the effects of prenatal stress on early neuro behavior, stress reactivity and learning performance in rhesus monkeys. Either a noise stressor or ACTH treatment was administered to pregnant monkeys during specific periods of pregnancy and offspring were examined repeatedly across development. In all three studies, the prenatally stressed monkeys showed reduced attention and impaired neuromotor functioning during the first month of life compared to controls from undisturbed pregnancies. When the monkeys were separated from their mothers or peers at 6-8 months of age, prenatally stressed monkeys exhibited more disturbance behavior and showed hypothalamic-pituitary-adrenal axis dysregulation. During adolescence, they exhibited impairments in learning, compared to controls.
Conformal strip excitation of dielectric resonator antenna (2000)

A new excitation scheme that employs a conducting conformal strip is proposed for dielectric resonator antenna (DRA) excitation. The new excitation scheme is successfully demonstrated by using a hemispherical DRA whose exact Green function is found using the mode-matching method. The moment method is used to solve the unknown strip current from which the input impedance is obtained. Novel recurrence formulas were obtained so that the impedance integrals are evaluated analytically. This solves the singularity problem of the Green function and substantially reduces the computation time. An experiment was carried out to verify the theory. The co- and cross-polarized field patterns are also shown. In addition, an experimental technique which deals with the problem of an air gap between the DRA and the ground plane is presented.
Intensive versus conventional blood pressure monitoring in a general practice population. The Blood Pressure Reduction in Danish General Practice trial: a randomized controlled parallel group trial (2017)

Clinical Trials NCT00244660.
Differences in Elastin and Elastolytic Enzymes between Men and Women with Abdominal Aortic Aneurysm (2014)

<b> <i>Background:</i> </b> Abdominal aortic aneurysms (AAAs) in women differ in some important aspects from those in men. The lower prevalence rate, higher rupture rate and potentially increased growth rate in women with AAA suggest gender to be of importance for aneurysm development and progression. The aim of the study was to analyze wall properties with respect to synthesis and destruction of elastin in men and women with AAA, with and without an intraluminal thrombus. <b> <i>Methods:</i> </b> Patient characteristics and aneurysm wall biopsies were collected from all women (<i>n</i> = 14) treated with open repair for AAA, 2008-2012, and men with similar aneurysm diameter and similar age (<i>n</i> = 23) treated during the same time period. The expressions of elastin, matrix metalloproteinase (MMP)-2 and -9, and cathepsin K were quantified by immunohistochemistry, Western blot, and gene expression analysis on the aneurysm wall. <b> <i>Results:</i> </b> The protein expression of elastin was less in women than in men in the non-thrombus-covered aneurysm wall. In addition, the protein and mRNA expressions of MMP-9 were higher in women (−0.83 versus 0.09, <i>P</i> = 0.041). There was no difference in elastin and elastolytic enzymes between men and women in the thrombus-covered aneurysm wall. <b> <i>Conclusion:</i> </b> Less elastin in the non-thrombus-covered aneurysm wall in women than that in men, and the simultaneous higher level of MMP-9, suggest differences in the elastolytic process in AAA between the sexes.
Effect of Oxygen Vacancy on the Conduction Modulation Linearity and Classification Accuracy of Pr0.7Ca0.3MnO3 Memristor (2021)

An amorphous Pr<sub>0.7</sub>Ca<sub>0.3</sub>MnO<sub>3</sub> (PCMO) film was grown on a TiN/SiO<sub>2</sub>/Si (TiN-Si) substrate at 300 °C and at an oxygen pressure (OP) of 100 mTorr. This PCMO memristor showed typical bipolar switching characteristics, which were attributed to the generation and disruption of oxygen vacancy (OV) filaments. Fabrication of the PCMO memristor at a high OP resulted in nonlinear conduction modulation with the application of equivalent pulses. However, the memristor fabricated at a low OP of 100 mTorr exhibited linear conduction modulation. The linearity of this memristor improved because the growth and disruption of the OV filaments were mostly determined by the redox reaction of OV owing to the presence of numerous OVs in this PCMO film. Furthermore, simulation using a convolutional neural network revealed that this PCMO memristor has enhanced classification performance owing to its linear conduction modulation. This memristor also exhibited several biological synaptic characteristics, indicating that an amorphous PCMO thin film fabricated at a low OP would be a suitable candidate for artificial synapses.
Synthesis, Characterization, and Interfacial Behaviors of Poly(oxyethylene)-Grafted SEBS Copolymers (1999)

Poly(oxyalkylene) blocks (POA) were synthetically grafted onto polystyrene-b-poly(ethylene/butylene)-b-polystyrene (SEBS) by the reaction of the maleated SEBS and various poly(oxyalkylene)amines. Structurally, the prepared comb-branch copolymers consist of a hydrophobic SEBS triblock backbone (approximate 45 000 MW with ∼29 wt % of styrene content) and multiple poly(oxyethylene) (POE) or poly(oxypropylene) (POP) pendants (in the range of 2000−6000 MW for each pendant). The hydrophilicity was probed by measuring the polymer surface resistivity from 1011.4 to 108.1 Ω/sq, depending on the pendant structures. In toluene or hexane, these copolymers formed very stable multiple emulsions with water as observed by an optical microscope. The copolymers were capable of reducing interfacial tension of toluene/water, in one example, from 31 to 7.4 dyn/cm by adding the copolymer at 3 × 10-2 g/100 mL concentration. At very low concentration (3 × 10-4 g/100 mL), these copolymers exhibited high efficiency in reducing interfacial tensions up to 17.5 dyn/cm, but slowly reaching the equilibrium over a 10-h period. In comparison, the commercially available Span 60 surfactant (HLB = 4.7) at the same concentration can only reduce to 28.5 dyn/cm. These phenomena are rationalized by the collective noncovalent bond interactions, predominantly the π−π interaction of the polystyrene block with toluene and the hydrogen bonding of the POE segments with water molecules.
Potential resource evaluation of sandstone-type uranium by the method of comprehensive geological information of typical deposit——A case study of interlayer oxidation zone type uranium deposit in the south of Yili basin (2011)

According to the principle the comprehensive geological information,and the characters of sandstone-type uranium mineralization,the authors summarized the method of uranium resource evaluation and applied it to the interlayer oxidation zone type uranium deposit in the south of Yili basin.Through data collection and analysis,construction of prediction evaluation model,assemblage and screening of the prediction variables,calculation of ore-formation favorability delineation of prediction zone,and the estimation of resource amount,the interlayer oxidation zone type uranium resource in the south of Yili basin is quantitatively evaluated in this paper.
USING ACCESS MANAGEMENT TO HELP RECLAIM A VILLAGE'S PUBLIC REALM (1998)

For more than 20 years, the town of Gorham, Maine, has been grappling with increased commuter and commercial traffic along its one-third mi (0.5 km) long village center on Main Street, which is both the traditional main street and a major regional roadway. Striking the balance to achieve a quality Main Street involved acknowledging up front that tradeoffs would have to be made. Maximizing either traffic flow or pedestrian accommodations would not result in a project that met the established goals or recognized constraints. Throughout the process of developing recommendations, it was surprising to recognize how many of the pedestrian improvements aided traffic considerations and vice versa. Reducing or closing curb cuts as part of the access management plan (a traffic improvement) also increases the amount of space available for sidewalks and landscaping treatments in the public right of way. This reduces the number of potential vehicle-vehicle and vehicle-pedestrian conflict points. Eliminating driveways means more space adjacent to buildings can be devoted to landscaping. Bumpouts at crosswalks (a pedestrian improvement) more effectively define areas near intersections where there should be no parking, which also improves sight distance for cars exiting from side streets.
Drones, Smartphones and Sensors to Face Natural Disasters (2018)

International audience
O2‐04–01: Combination of insulin with other diabetes medication is associated with lower Alzheimer neuropathology (2008)

Diabetes has been consistently associated with Alzheimer's disease. To examine the association between treatment for diabetes and Alzheimer's disease neuropathology. This postmortem study matched 124 subjects with diabetes to 124 without diabetes from the Mount Sinai School of Medicine Brain Bank, on age (mean=81.2+9.3), sex (57.3%, F), and severity of dementia (clinical dementia rating (CDR), (2.4+1.7)). Densities of neuritic plaques (NPs) and of neurofibrillary tangles (NFTs) were assessed in several neocortical regions and in the hippocampus, entorhinal cortex, and amygdala. Diabetic subjects were classified according to their recorded lifetime anti-diabetic medications: none (n=29), insulin only (n=49), diabetes medications other than insulin only (n=28), or concomitant use of both insulin and any oral anti-diabetic medications (n=18). For each dependent variable, analysis of covariance controlling for age at death, sex, and CDR distinguished among the non-diabetics and four diabetic subgroups. There were significant differences among the five groups for NP ratings in the entorhinal cortex (p=.003), amygdala (p=.009), and overall NP (p=.014) as well as counts of NPs in all regions examined (p-values ranging from .009 to .04). NP ratings in the hippocampus (p=.057) and the combined neocortical measure (p=.052) approached significance. In each analysis, the concomitant medication group had significantly fewer NPs (∼20%) than any of the other groups, which were relatively similar. No significant NFT differences were found. The results of this study suggest that combination of insulin with other diabetes medication is associated with a substantial reduction in brain NP density consistent with the effects of both on the neurobiology of insulin. This suggests therapeutic targeting of insulin signaling pathways of the brain for the reduction of Aβ associated neuropathology of AD.
Imaging and local current transport measurements of AlInP quantum dots grown on GaP (2000)

Individual AlInP self-assembled quantum dots grown on a (100) GaP substrate are imaged and probed using ballistic electron emission microscopy (BEEM). The excellent nanometer scale lateral resolution of BEEM is utilized to inject carriers directly into a single quantum dot, and thus, current transport through the dot investigated without any direct electrical contact. The BEEM spectra taken on and off the dot revealed a local conduction-band offset between GaP and AlInP with a barrier height of ΔEc∼0.13±0.01 eV.
Photodegradation of 4-chlorophenol sensitized by wastederived soluble organic substances using experimental design (2011)

Advanced Oxidation Techniques represent an alternative to more traditional water treatments since they are able to promote the degradation of organic substrates, leading to their complete mineralization. These processes are based on the production of highly reactive species (mainly radicals) and are often light assisted. Among the compounds able to photogenerate reactive species, humic and fulvic acids (HS) have been widely studied in order to understand the water autopurification mechanisms. It is thus in principle possible to propose the use of HS in wastewater photodegradation treatments; however neither waters nor soils can be considered as exploitable source of HS. The organic fraction of urban wastes has been demonstrated to be an interesting source of soluble organic substances (SOS), structurally similar to HS and exhibiting good photosensitizing properties. In the present research the photodegradation of 4-chlorophenol (4-CP), a toxic and hardly biodegradable pollutant, has been studied in the presence of one type of SOS. In order to optimize experimental conditions and to evaluate possible synergistic effects with other photoactive compounds (TiO2 and H2O2) a chemometric approach has been chosen. Two designs of experiments (D-Optimal, DoE) have been planned and the following parameters have been considered: 4-CP concentration (from 10 to 100 mg L-1), SOS concentration (from 0 to 1000 mg L-1), TiO2 concentration (from 0 to 500 mg L-1) or H2O2 concentration (from 0 to 10-2 M), cut-off filter for the light source (340 nm, 400 nm and without filter). By mean of the Modde software, 39 experiments were selected for the TiO2-DoE and 25 experiments for the H2O2-DoE. The resulting response surfaces evidenced that, in the presence of TiO2, a competition for the active photogenerated species seems to take place between 4-CP and SOS, since also SOS can be in turn photodegraded. On the contrary, a synergistic effect between SOS and H2O2 occurs, when the 400 nm cut-off filter is used. After three hours of irradiation 25% of 4-CP abatement was achieved in the presence of 500 mg L-1 of SOS, 35 % was achieved in the presence of 5 mM of H2O2, whereas 45% of 4-CP abatement was obtained in the presence of both SOS and H2O2 at the above mentioned concentrations. These results encourage the use of chemometric tools and give useful information for a possible scale-up of the process in pilot plants exploiting the solar light as radiation source
Microstructural evolution of a silicon oxide phase in a perfluorosulfonic acid ionomer by an in situ sol-gel reaction. 3. Thermal analysis studies (1990)

Microcomposite membranes were produced via the in situ diffusion-controlled, acidcatalyzed sol-gel reaction for tetraethoxysilane in prehydrated and methanol-swollen Nafion perfluorosulfonic acid films. The thermal behavior of these microcomposites was investigated using thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC). It was found by TGA that significant thermochemical degradation begins at around 350 "C and then takes place in at least three stages for both filled and unfilled membranes. Two strong thermal transitions, identified with the polar cluster and microcrystalline domains, in the predegradative temperature regime above 30 "C, were identified by DSC for all the microcomposite as well as the unfilled membranes. However, upon annealing at a temperature just below the "cluster transition temperature" and then quenching, this transition becomes suppressed for all membranes. It appears that both the polar and microcrystalline domains remain quite intact in spite of the in situ growth of the silicon oxide phase at the filler levels investigated. This observation reinforces our earlier hypothesis of the three-dimensional template action of Nafion's natural microphase-separated morphology in directing the final morphology of the inorganic phase.
Fan-shaped tracker (FsT) for particle trajectory reconstruction (2019)

With the development of super-resolution fluorescence microscopy, complex dynamic processes in living cells can be observed and recorded with unprecedented temporal and spatial resolution. Single particle tracking is the most important step to explore the relationship between the spatio-temporal dynamics of subcellular molecules and their functions. Although previous studies have developed single particle tracking algorithms to quantitatively analyze particle dynamics in cell, traditional tracking methods have poor performance when dealing with intersecting trajectories. This can be attributed to two main reasons: 1) They do not have point compensation process for overlapping points; 2) They use inefficient motion prediction models. In this paper, we presented a novel Fan-shaped Tracker (FsT) algorithm to reconstruct the trajectories of subcellular molecules in living cells. We proposed a customized point compensation method for overlapping points based on the fan-shape motion trend of the particles to solve the merging trajectory problem. Furthermore, we compared the performance of our Fan-shaped Tracker with five state-of-the-art tracking algorithms in simulated time-lapse movies with variable imaging quality. Our results showed that the Fan-shaped Tracker achieves better performance than other reported methods as we systematically evaluated using a set of standard evaluation parameters. We anticipate that our FsT method will have vast applications in tracking of moving objects in cell.
On pressure estimates for the Navier-Stokes equations (2018)

This paper presents a simple, general technique to prove finite element method (FEM) pressure stability and convergence. Typically, pressure estimates are ignored in the literature. However, full reliability of a numerical method is not established unless the solution pair $(u,p)$ is treated. The simplicity of the proposed technique puts pressure estimates within reach of many existing and future numerical methods and lends itself to the numerical analyst's toolbox.
Sphere Formation (Osteosphere/Sarcopshere) Assay (2012)

Self-renewing cells from adult tissue (such as bone) that represent a progenitor population can be grown in suspension cultures in the presence of defined serum-free medium. Progenitor cells can be identified by this property of anchorage-independent growth in suspension cultures. These spherical clusters of progenitor bone cells growing under non-adherent conditions are called osteospheres. Such progenitor populations often possess characteristics of multipotency and can differentiate into multiple mesenchymal lineages. Cancer cells capable of growing in suspension have also been reported in osteosarcomas, tumors of the bone tissue. These spherical colonies formed from single cells (clonal) in non-adherent conditions are generally considered to represent self-renewing, stem-like cells and can be employed for other assays such as multipotency and limiting dilution analysis (LDA)., 来自代表祖细胞群体的成体组织（例如骨）的自我更新细胞可以在确定的无血清培养基的存在下在悬浮培养物中生长。 祖细胞可以通过悬浮培养物中锚定非依赖性生长的这种性质来鉴定。 这些在非粘附条件下生长的祖细胞骨细胞的球形簇称为骨干球。 这样的祖细胞群通常具有多能性的特征并且可以分化成多个间充质谱系。 在骨肉瘤，骨组织的肿瘤中也报道了能够在悬浮液中生长的癌细胞。 在非粘附条件下由单细胞（克隆）形成的这些球形菌落通常被认为代表自我更新的干细胞样细胞，并且可以用于其它测定，例如多能性和有限稀释分析（LDA）。
UM PENSADOR ESSENCIAL DA COMUNICAÇÃO (2007)

Baudrillard é reconhecidamente “amável” como uma dessas partículas pesadas que tiveram o papel de ver, interpretar e analisar a sociedade em que viveu. Tarefa difícil e muitas vezes incompreendida, principalmente pela resistente resistência a toda e qualquer mudança de padrões acadêmicos ou a todo vocabulário que não se anuncie como socialmente otimista. Por esta razão, seu pensamento, suas “anunciações” foram e são, por alguns, tão erroneamente interpretados. Um crítico dessa sociedade em que o sentido é mercadoria barata não pode ser considerado um otimista. Mas pessimista, também não: Jean Baudrillard certamente poderia ser considerado um niilista, no sentido adotado pelo filósofo italiano Gianni Vattimo.
REST API example generation using Javadoc (2017)

Formatting and editing documentation can be a tedious process regardless of how well your documentation templates are made. Especially, keeping the code examples up-to-date can be time-consuming and error-prone. The research presented in this article describes a Javadoc extension that can be used to produce example data in combination with automatically generated API method call examples, and explains how the APIs in our implementation are organized to further ease the automatic documentation process. The primary goal is to make generating method call examples for (RESTful) web services easier. The method has been used in the implementation of a media content analysis service, and the experiences, advantages of using the described approach are discussed in this article. The method allows easier validation and maintenance for the documentation of method usage examples with a downside of an increased workload in the implementation of software components required for the automatic documentation process.
Muscling transplants into mice. (1996)

Creating “immune-privileged” pockets where a new heart, liver, or kidney graft would be safe from immunologic rejection has long been a transplant biologist9s dream. Now researchers have devised a way to do that by genetically engineering muscle cells to produce a key ingredient of immune privilege: a protein known as the Fas ligand, or FasL, that can induce immune cells to kill themselves. On page 109, they report using engineered muscle cells to protect transplants of islet cells, the insulin-producing cells of the pancreas, in diabetic mice—a feat that could lead to a treatment for some human diabetics and perhaps to a general strategy for guarding transplants against rejection.
Improved efficiency of a hybrid CO2 laser as a result of increased TEM00 mode filling factor (2004)

Considerable improvement in the operating efficiency of a hybrid CO2 laser has been achieved by increasing the TEM00 mode filling factor in the TEA section. The usage of helium-free gas mixture in the TEA section restricted the width of the glow discharge to the central zone in the interelectrode region allowing the oscillating TEM00 mode to experience a higher gain in the TEA section resulting in an improved performance of the laser.
A comparative study of LRRK2, PINK1 and genetically undefined familial Parkinson's disease (2009)

Genetic classification of Parkinson's disease (PD) subtypes may become the preferred diagnostic tool for neurologists. Herein we compare clinical features from a large cohort of patients with familial PD of unknown aetiology or attributable to distinct genetic forms. Comprehensive neurological examinations were performed in 231 familial PD patients from Tunisia. Analysis was previously performed to screen for mutations in leucine rich repeat kinase 2 (LRRK2), PTEN induced kinase 1 (PINK1) and parkin (PRKN). Clinical features were compared between patients with genetically undefined PD (n=107) and those with LRRK2 (n=73) and PINK1 (n=42) mutations using regression analyses adjusted for gender, age of onset and disease duration. PRKN cases (n=9) were too few for meaningful statistical analysis. In comparison with genetically undefined patients, LRRK2 mutation carriers had more severe motor symptoms (median Unified Parkinson's Disease Rating Scale scores approximately 1.6 times higher, p<0.001), a higher rate of dyskinesia (OR 4.21, p=0.002) and use of dopamine agonists (OR 3.64, p<0.001), and less postural tremor (OR 0.21, p<0.001). PINK1 mutation carriers presented an increased rate of drug induced dyskinesia (OR 3.81, p=0.007) and a lower rate of postural tremor (OR 0.16, p<0.001) than genetically undefined patients. As expected, PINK1 patients had younger ages and ages at disease onset, and a longer disease duration compared with LRRK2 mutation carriers and genetically undefined patients. Clinical differences between LRRK2, PINK1 and genetically undefined familial PD appear more pronounced than previously appreciated, and may prove useful in clinical practice. As future therapies are targeted to specific protein abnormalities, identifying the genetic causes and associated clinical and pathological features will determine diagnosis, preventative medicine and drug intervention strategies.