gebhart/patrepeval huggingface dataset:
<title>Sensitivity of detection of bacteria with fluorescent and luminescent phenotypes using different instruments</title> (2000)

The problem of bacterial enumeration in different samples is of great importance in many fields of research. Construction of recombinant fluorescent and luminescent bacteria that can be easily detected by nondestructive instrumental methods proves us with an opportunity to monitor bacteria in a wide variety of clinical, environmental and food samples in real time. Three different labels were employed: Green Fluorescent Protein (GFP), Bacterial luciferase (BL) and Firefly Luciferase (FFL). Both plasmid and chromosomal transformants of different strains of E. coli, P. putida and S. enteritidis were used. For the detection of the in vivo GFP the Shimadzu RF 540 spectrofluorimeter, Labsystems FL- 500 plate fluorimeter and Night Owl LB 98 CCD-camera from EG and G Berthold supplied with excitation light source and proper spectral filters both in macroscopic and microscopic mode were used. For the detection of in vivo luminescence of BL and FFL, tube luminometer BG-P from GEM Biomedical Inc., luminometric plate reader from BioOrbit, BIQ Bioview CCD camera from Cambridge Imaging Ltd and Night Owl LB 98 CCD camera both in macroscopic and microscopic mode were used. The expression levels of the labels, their stability, stability of the signal and detection limits of tagged bacteria were investigated. The detection limits for GFP tagged bacteria were 5 X 10<SUP>4</SUP> - 6 X 10<SUP>6</SUP>, for BL tagged bacteria 5 X 10<SUP>2</SUP> - 2 X 10<SUP>5</SUP>, and for FFL tagged bacteria - 4 X 10<SUP>3</SUP> - 10<SUP>6</SUP> CFU/ml, depending on the instrument used. Single bacteria could be detected with the help of the Night Owl in the microscopic mode.
3D Optical Manipulation of a Single Electron Spin (2013)

We optically trap individual nanodiamonds hosting a single Nitrogen Vacancy center and demonstrate a novel route for both non-invasive 3D vectorial magnetometry and sensing of the local density of states in a liquid environment.
Efficient Alternatives to the Ephraim and Malah Suppression Rule for Audio Signal Enhancement (2003)

Audio signal enhancement often involves the application of a time-varying filter, or suppression rule, to the frequency-domain transform of a corrupted signal. Here we address suppression rules derived under a Gaussian model and interpret them as spectral estimators in a Bayesian statistical framework. With regard to the optimal spectral amplitude estimator of Ephraim and Malah, we show that under the same modelling assumptions, alternative methods of Bayesian estimation lead to much simpler suppression rules exhibiting similarly effective behaviour. We derive three of such rules and demonstrate that, in addition to permitting a more straightforward implementation, they yield a more intuitive interpretation of the Ephraim and Malah solution.
Airborne Doppler lidar wind measuring system: Application to atmospheric problems (1980)

The ability to map velocities over a large area on one side of the aircraft flight path offers a number of opportunities to elucidate scientific questions related to atmospheric dynamics. Several types of experiments which are possible are described.
Non‐melanoma skin cancer as a clinical marker for internal malignancies: a nationwide population‐based cohort study (2019)

Patients with NMSC require careful screening and follow-up for internal malignancy.
Abstract IA07: Genetic engineering of therapeutic T cells using synthetic nanoparticles (2018)

Abstract Despite the obvious advantages afforded by targeted T-cell cancer therapies (compared with the blunt instruments of chemotherapy, radiotherapy, and surgery), the complexity and costs involved in producing genetically modified lymphocytes remain major obstacles to their implementation as standard of care. Work in our laboratory aims to obviate these problems by integrating materials science, immunology, and gene therapy to make cellular immunotherapy more effective, practical, and widespread. In this talk, I will highlight two examples: In the first segment, I will describe a new strategy to genetically imprint therapeutically desirable phenotypes in cultured T cells, simply by mixing them with a targeted mRNA-carrying nanoreagent. When they are added to a culture of cells, these engineered nanoparticles bind to targeted T cell populations and induce major biologic effects on the basis of transient “hit-and-run” gene therapy without the necessity of resorting to complicated protocols or complex ancillary equipment. Our approach provides significant advantages over those currently used to create cytoreagents (i.e., viral transfection and electroporation), which require specialized equipment and demanding production steps. In the second part of my presentation, I will introduce a new injectable reagent our group developed that that can quickly program tumor-recognizing capabilities into circulating T cells without the need for laboratory manipulations. We demonstrate that, once they are adapted with lymphocyte-targeting ligands, polymeric nanocarriers can selectively deliver leukemia-specific chimeric antigen receptor (CAR) genes into host T cells in situ. These nanoparticles are easy to manufacture and are stable, which simplifies long-term storage and reduces cost. This technology may therefore provide a practical, broadly applicable treatment that can generate antitumor immunity at the time of diagnosis in a variety of settings. Citation Format: Howell F. Moffett, Tyrel T. Smith, Matthias T. Stephan. Genetic engineering of therapeutic T cells using synthetic nanoparticles [abstract]. In: Proceedings of the AACR Special Conference on Tumor Immunology and Immunotherapy; 2017 Oct 1-4; Boston, MA. Philadelphia (PA): AACR; Cancer Immunol Res 2018;6(9 Suppl):Abstract nr IA07.
Bubble levitation and translation under single-bubble sonoluminescence conditions (2003)

Bubble levitation in an acoustic standing wave is re-examined for conditions relevant to single-bubble sonoluminescence. Unlike a previous examination [Matula et al., J. Acoust. Soc. Am. 102, 1522-1527 (1997)], the stable parameter space [Pa,R0] is accounted for in this realization. Forces such as the added mass force and drag are included, and the results are compared with a simple force balance that equates the Bjerknes force to the buoyancy force. Under normal sonoluminescence conditions, the comparison is quite favorable. A more complete accounting of the forces shows that a stably levitated bubble does undergo periodic translational motion. The asymmetries associated with translational motion are hypothesized to generate instabilities in the spherical shape of the bubble. A reduction in gravity results in reduced translational motion. It is hypothesized that such conditions may lead to increased light output from sonoluminescing bubbles.
Synthesis of Cycloheptanone by a Nitromethane Condensation Sequence (1951)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of Cycloheptanone by a Nitromethane Condensation SequenceHyp J. Dauben Jr., Howard J. Ringold, Robert H. Wade, and Arthur G. Anderson Jr.Cite this: J. Am. Chem. Soc. 1951, 73, 5, 2359–2361Publication Date (Print):May 1, 1951Publication History Published online1 May 2002Published inissue 1 May 1951https://doi.org/10.1021/ja01149a513Request reuse permissions Your access to this publication has been provided by Learn MoreArticle Views350Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (435 KB) Get e-Alertsclose Get e-Alerts
Effect of temperature on growth and activity of Aeromonas spp. and mixed bacterial populations in the Anacostia River (1981)

During the winter months, total bacterial counts in the water column and in the sediment in the Anacostia River were two- to eightfold higher than at other times of the year, whereas Aeromonas spp. decreased in number of several orders of magnitude. This significant decrease in number in the Anacostia River during the cold months of the year can be explained by the low metabolic activity of Aeromonas at low temperatures.
NIST Open Machine Translation 2008 Evaluation: Stanford University's System Description (2008)

This document describes Stanford University’s first entry into a NIST MT evaluation. Our entry to the 2008 evaluation mainly focused on establishing a competent baseline with a phrase-based system similar to (Och and Ney, 2004; Koehn et al., 2007). In a three-week effort prior to the evaluation, our attention focused on scaling up our system to exploit nearly all Chinese-English parallel data permissible under the constrained track, incorporating competitive language models into the decoder using Gigaword and Google n-grams, evaluating Chinese word segmentation models, and incorporating a document classifier as a pre-processing stage to the decoder.
Separation, size reduction, and processing of XLPE from electrical transmission and distribution cable (2000)

Abstract The recycling of power transmission cable insulated with crosslinked PE (XLPE) was investigated by using different methods of separation and reprocessing. Separation was attempted by thermo‐chemical, thermo‐mechanical and microwave‐mechanical means, the latter being the most successful. A mechanism encompassing all of these was formulated. Compression molding, extrusion, and injection molding with and without preheating of the material were also investigated. It was found that by preheating the XLPE and injection molding under high injection pressure, the neat XLPE could be formed into shapes with tensile strengths equal to that of the original insulation. In view of available observations, possible mechanisms for the flow and reconsolidation of XLPE crumb are proposed and discussed.
[Blood transfusion in heart surgery]. (1990)

We have studied the effect of blood-saving measures in open heart surgery. Such measures were introduced in 1987. All fluids administered on the day of operation and on the first postoperative day were registered in all cardiac patients operated during one month in 1986, 1987, 1988. In 1986 the patients were exposed to a median of 21 donors while in 1988 they were exposed to a median of 2 donors. The reduction in transfusions was achieved by substituting plasma by polygeline, by giving thrombocytes only when there was a low thrombocyte count and by accepting a hemoglobin value of 9 g/100 ml before transfusion of erythrocytes. In 1988 most postoperatively drained blood was retransfused using a Sorensen retransfusion set. The reduction in transfusions has reduced the cost of each open heart operation by NOK 11,662.
Collecting Duct Carcinoma of the Kidney (2001)

Medullary involvement and an infiltrative appearance are common findings on cross-sectional imaging and may suggest the diagnosis of collecting duct carcinoma. In large tumors, however, these features are frequently overshadowed by an exophytic or expansile component that cannot be distinguished from the more common cortical renal cell carcinoma.
EUV spectral analysis of ns-laser produced bismuth plasmas at 8-17 nm (2017)

Extreme ultraviolet (EUV) spectra from laser produced bismuth plasmas were recorded in the 8-17 nm spectral region using a Nd:YAG laser with a pulse length of 8 ns operating at a range of laser power densities. Due to the broad-band emission at 8-17 nm, bismuth plasmas show promise as sources of quasicontinuous radiation in the extreme ultraviolet. When varying the incident laser power density, ionic populations of Bi ions at different power densities were estimated by the collisional-radiative (CR) model for explanation of changes in the spectral profile. Comparison of experimental spectra with atomic structure calculations using the Hartree-Fock with configuration interaction (HFCI) code of Cowan was performed in order to identify most of the features in the spectra.
Electric Power Transmission: Background and Policy Issues (2009)

This report discusses electric power transmission and related policy issues. Transmission is a prominent federal issue because of a perceived need to improve reliability and reduce costs, transmission's role in meeting national energy goals (such as increased use of renewable electricity), and the potential efficiency advantages of "smart grid" modernization.
Isoform selective inhibition and inactivation of human cytochrome P450s by methylenedioxyphenyl compounds (1999)

1. A series of methylenedioxyphenyl compounds were evaluated for their inhibitory and inactivation effects on nine human cytochrome P450 (CYP) activities using microsomes from human B-lymphoblast cells expressing specific human CYP isoforms. 2. Methylenedioxyphenyl compounds which possess a bulky structure such as 1,4-benzothiazine showed substantial inhibition of S-warfarin 7-hydroxylation catalysed by CYP2C9, S-mephenytoin 4'-hydroxylation by CYP2C19, bufuralol 1'-hydroxylation by CYP2D6, and testosterone 6beta-hydroxylation by CYP3A4. Regarding ethoxyresorufin O-deethylation catalysed by CYP1A1 and benzyloxyresorufin O-dealkylation by CYP2B6, the subtle change of a substitution of the 1,4-benzothiazine structure affected the inhibition selectivity. Ethoxyresorufin O-deethylation by CYP1A2, coumarin 7-hydroxylation by CYP2A6, and chlorzoxazone 6-hydroxylation by CYP2E1 were not inhibited by almost any of the methylenedioxyphenyl compounds. The inhibitory effects of methylenedioxyphenyl compounds that possess a short chain amino group on the human CYP isoforms were not significant. 3. The methylenedioxyphenyl compounds inactivated CYP1A1 (k(inact) = 0.034 min(-1) and K(i) = 0.81 microM), CYP2C9 (k(inact) = 0.041 and 0.042 min(-1) and K(i) = 0.56 and 0.15 microM), CYP2D6 (k(inact) = 0.044-0.339 min(-1) and K(i) = 0.21-19.88 microM), and CYP3A4 (k(inact) = 0.076-0.251 min(-1) and K(i) = 0.25-0.69 microM). These results suggested that the methylenedioxyphenyl compounds investigated in this study would be potent mechanism-based inactivators of these human CYP isoforms. In contrast, CYP2B6 and CYP2C19 were not inactivated. 4. The present study suggested that the selectivity of inhibition or inactivation of human CYP isoforms by methylenedioxyphenyl compounds may vary according to the structure of the side chain.
Zentren der Methanaktivierung auf Oberflächen von Lithium‐dotiertem MgO (2014)

Abstract Die mittels Dichtefunktionaltheorie berechneten Energiebarrieren für die H‐Abstraktion durch Sauerstoffradikale in Li‐dotiertem MgO sind viel kleiner (12±6 kJ mol −1 ) als die Barrieren, die man bei unterschiedlichen Methanaktivierungsexperimenten findet (80–160 kJ mol −1 ). Das nährt weitere Zweifel an Lunsfords Hypothese, dass Li + O .− ‐Paare die aktiven Zentren sind. Temperaturprogrammierte oxidative Kupplungsreaktionen von Methan (OCM) zeigen, dass bei reinem und Li‐dotiertem MgO die gleichen Zentren für die Reaktion verantwortlich sind. MgO‐Katalysatoren, die durch Sol‐Gel‐Synthese hergestellt wurden, zeigen große Unterschiede zwischen anfänglicher Aktivität und der Aktivität im stationären Zustand. Transmissionselektronenmikroskopie zeigt, dass damit substanzielle morphologische Veränderungen und Restrukturierungen der Oberfläche einhergehen. Berechnungen an (MgO) 9 ‐Clustermodellen ergeben, dass CH 4 heterolytisch an Mg 2+ O 2− ‐Paaren chemisorbiert wird, die sich an Stufen oder Ecken befinden. Die homolytische Freisetzung von Methylradikalen erfordert jedoch die Anwesenheit von O 2 auf der Oberfläche.
Distributed DNN based Processing for Uplink Could-RAN (2021)

This paper investigates the uplink reception in the cloud radio access network (C-RAN) with finite-capacity fronthaul links. The latter is an emerging network that transfers the computing load from the radio heads (RHs) to the central processor (CP) unit. Due to the prohibitive complexity of computations, the most efficient uplink C-RAN schemes are challenging to be implemented in practical systems. Using deep neural networks (DNNs), we propose a new and low complex distributed processing for uplink C-RAN subject to some quantification rules. The objective of our architecture, called TDNet, is to optimize the processing jointly at the RHs and the CP side. Our goal is not to solve signal detection in multi-antenna systems. Instead, our work aims to find a helpful transformation scheme at the RH side before quantization. A correspondent decoding scheme at the CP side considers the quantization scheme. Inspired by the projected gradient descent algorithm, TDNet is designed as a distributed DNN with sparse connections. Numerical results are provided and show that our scheme outperforms linear receivers such as the zero-forcing (ZF). It also achieves near-optimal performance compared to the sphere decoder (SD) algorithm, especially for a low-to-moderate number of quantization bits.
Energy-Efficient Locomotion Strategies and Performance Benchmarks using Point Mass Tensegrity Dynamics (2019)

This work introduces a novel 12-motor paired-cable actuation scheme to achieve rolling locomotion with a spherical tensegrity structure. Using a new point mass tensegrity dynamic formulation which we present, we utilize Model Predictive Control to generate optimal state-action trajectories for benchmark evaluation. In particular, locomotive performance is assessed based on the practical criteria of rolling speed, energy efficiency, and directional trajectory-tracking accuracy. Through simulation of 6-motor, 12-motor paired cable, and 24-motor fully-actuated policies, we demonstrate that the 12-motor schema is superior to the 6-motor policy in all benchmark categories, comparable to the 24-motor policy in rolling speed, and is over five times more energy efficient than the fully-actuated 24-motor configuration.
A Downhole Wireline Module for the Measurement of Bubble Point Pressure (2019)

Abstract The accuracy of the phase envelope calculated for a black oil sample strongly depends upon the quality and type of information used to optimize the equation of state (EOS). Possible inputs for EOS tuning include (but is not limited to) composition from a chromatogram or optical absorbance, density, saturation pressure (bubble or dew point pressure), and the relative volumes of liquid and gas. In this manuscript, we describe a workflow using a system of microsensors that our group has previously published that accurately measures fluid properties from which the phase envelopes of several black oil samples are calculated and refined.
Molecular cloning of G protein α subunits from the central nervous system of the mollusc Lymnaea stagnalis (1992)

The central nervous system of the pond snail, Lymnaea stagnalis, contains many large, identified neurons which can be easily manipulated making it an advantageous model system to elucidate in vivo the architecture of neuronal signal transduction pathways. We have isolated three cDNA clones encoding G protein alpha subunits that are expressed in the Lymnaea CNS, i.e. G alpha o, G alpha s and G alpha i. The deduced proteins exhibit a very high degree of sequence identity to their vertebrate and invertebrate counterparts. The strong conservation of G protein alpha subunits suggests that functional insights into G protein-mediated signalling routes obtained through the experimental amenability of the Lymnaea CNS will have relevance for similar pathways in the mammalian brain.
Identification of a Specific Chaperone for SptP, a Substrate of the Centisome 63 Type III Secretion System of Salmonella typhimurium (1998)

Salmonella typhimurium uses of a type III protein secretion system encoded at centisome 63 of its chromosome to deliver effector molecule into the host cell. These proteins stimulate host cell responses such as reorganization of the actin cytoskeleton and activation of transcription factors. One of these effector proteins is SptP, a tyrosine phosphatase that causes disruption of the host cell actin cytoskeleton. A characteristic feature of many substrates of type III secretion systems is their association with specific cytoplasmic chaperones which appears to be required for secretion and/or translocation of these proteins into the host cell. We report here the identification of SicP, a 13-kDa acidic polypeptide that is encoded immediately upstream of sptP. A loss-of-function mutation in sicP resulted in drastically reduced levels of SptP but did not affect sptP expression, indicating that SicP exerts its effect posttranscriptionally. Pulse-chase experiments demonstrated that the loss of SicP leads to increased degradation of SptP. In addition, we show that SicP binds to SptP directly and that the binding site is located between residues 15 and 100 of the tyrosine phosphatase. Taken together, these results indicate that SicP acts as a specific chaperone for SptP.
Nonlinear Optical Borate Crystals (2012)

This clear and self-contained review of the last four decades of research highlights in the hot field of nonlinear optical (NLO) crystals, particularly of borate-based ultraviolet and deep-ultraviolet NLO crystals, covers three major subjects: the structure-property relationship in borate crystals, the structural and optical characteristics of various promising borate crystals, and their fruitful applications in a wide range of scientific and technological fields. Edited by the discoverers and users of these optical borate crystals, this is a readily accessible reading for semiconductor, applied and solid state physicists, materials scientists, solid state chemists, manufacturers of optoelectronic devices, and those working in the optical industry.
Highly Sustainable Zinc Anodes for a Rechargeable Hybrid Aqueous Battery (2017)

The synthesis of novel zinc electrodes has been successfully implemented by using the electroplating method with the aid of inorganic additives in the electroplating solution. The selected inorganic additives are indium sulfate, tin oxide, and boric acid. From X-ray diffraction results, these synthesized zinc electrodes prefer (002) and/or (103) crystallographic orientations, representing basal morphology and high resistance to dendrite growth. The corrosion rates of these electroplated zinc samples decrease as much as 11 times smaller than the corrosion rate on zinc foil when the zinc materials are in contact with the aqueous electrolyte of a rechargeable hybrid aqueous battery (ReHAB). The ReHABs employing these anodes exhibit up to a threefold decrease in float charge current density after a seven-day constant-voltage charging at 2.1 V versus Zn<sup>2+</sup> /Zn. Furthermore, the capacity retention is up to 15 % higher than the performance of battery containing commercial Zn after 1000 cycles of charge-discharge. The significant advancements are attributed to the careful preparation of the anode, which contains appropriate crystallographic orientation and morphology.