gebhart/patrepeval huggingface dataset:
Semiotism by Offenbach’s mise-en Pratique of Performance with music (2012)

음악을 논할 때 오펜바흐를 언급하지 않을 수 없다. 그는 엔터테이너였으며 음악을 신화와 기호의 소재이자 주제로 응용한 선구자다. 그가 작곡한 상당수의 무대음악은 후대의 음악가와 음악류의 공연들에 많은 영향을 미쳤다. 그가 사용한 음악적 상징성이나 신화적 기호가 19세기 프랑스의 정치와 음악적인 배경 속에서 어떻게 맥이 닿는지 알아보고 21세기적 가치로 고찰하는 것은 의미 있다. 특히 무대음악적 분야에서의 콘텐츠 생산성의 가치와 방식을 유추할 수 있는 것이다. 그가 사용한 양식은 두세기를 지나 오늘날 디지털시대의 이야기 방식과 음악적 결합에 있어서도 통용된다. 그런 측면에서 엔터테이너로서의 오펜바흐는 인정되고 위치되어야 한다.
Segmented Compressed Sampling for Analog-to-Information Conversion: Method and Performance Analysis (2010)

A new segmented compressed sampling (CS) method for analog-to-information conversion (AIC) is proposed. An analog signal measured by a number of parallel branches of mixers and integrators (BMIs), each characterized by a specific random sampling waveform, is first segmented in time into segments. Then the subsamples collected on different segments and different BMIs are reused so that a larger number of samples (at most ) than the number of BMIs is collected. This technique is shown to be equivalent to extending the measurement matrix, which consists of the BMI sampling waveforms, by adding new rows without actually increasing the number of BMIs. We prove that the extended measurement matrix satisfies the restricted isometry property with overwhelming probability if the original measurement matrix of BMI sampling waveforms satisfies it. We also prove that the signal recovery performance can be improved if our segmented CS-based AIC is used for sampling instead of the conventional AIC with the same number of BMIs. Therefore, the reconstruction quality can be improved by slightly increasing (by times) the sampling rate per each BMI. Simulation results verify the effectiveness of the proposed segmented CS method and the validity of our theoretical results. Particularly, our simulation results show significant signal recovery performance improvement when the segmented CS-based AIC is used instead of the conventional AIC with the same number of BMIs.
Linear and Non-Linear Methods in Optical Tomography (2000)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text S. R. Arridge, "Linear and Non-Linear Methods in Optical Tomography," in Biomedical Optical Spectroscopy and Diagnostics, T. Li, ed., Vol. 38 of OSA Trends in Optics and Photonics (Optica Publishing Group, 2000), paper MA1. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Anticancer attributes of desert plants (2012)

The ever-increasing emergence of the resistance of mammalian tumor cells to chemotherapy and its severe side effects reduces the clinical efficacy of a large variety of anticancer agents that are currently in use. Thus, despite the significant progress in cancer therapeutics in the last decades, the need to discover and to develop new, alternative, or synergistic anticancer agents remains. Cancer prevention or chemotherapy based on bioactive fractions or pure components derived from desert plants with known cancer-inhibiting properties suggests promising alternatives to current cancer therapy. Plants growing on low nutrient soils and/or under harsh climatic conditions, such as extreme temperatures, intense solar radiation, and water scarcity, are particularly susceptible to attack from reactive oxygen species and have evolved efficient antioxidation defense systems. The many examples of desert plants displaying anticancer effects as presented here indicates that the same defensive secondary metabolites protecting them against the harsh environment may also play a protective or a curative role against cancer, as they also do against diabetes, neurodegenerative, and other acute and chronic diseases. The present review highlights a plethora of studies focused on the antineoplastic properties of desert plants and their prinicipal phytochemicals, such as saponins, flavonoids, tannins, and terpenes. Although many desert plants have been investigated for their antitumor properties, there are many that still remain to be explored – a challenge for the prospective cancer therapy of the future.
Multivariate SPC Charts for Monitoring Batch Processes (1995)

The problem of using time-varying trajectory data measured on many process variables over the finite duration of a batch process is considered. Multiway principal-component analysis is used to compress the information contained in the data trajectories into low-dimensional spaces that describe the operation of past batches. This approach facilitates the analysis of operational and quality-control problems in past batches and allows for the development of multivariate statistical process control charts for on-line monitoring of the progress of new batches. Control limits for the proposed charts are developed using information from the historical reference distribution of past successful batches. The method is applied to data collected from an industrial batch polymerization reactor.
Deep molecular baskets : convergent syntheses of calix[4]naphthalenes via directed ortho metallation and Suzuki-Miyaura coupling reactions (2001)

Calix[4]naphthalenes are a new class of compounds which are analogous to the better-known calix[4]arenes, but have deeper cavities. These compounds, especially the endo calix[4]naphthalenes e.g., 31 can behave as baskets in their abilities to complex with neutral guest molecules such as [60]fullerene. This thesis describes the synthesis of such deep molecular baskets. -- Calix[4]naphthalene (31 ) was synthesized by self-condensation reactions of 6-tert -butyl-3-(hydroxymethyl)-2-naphthol ( 29 ). Various Lewis acids were evaluated in order to obtain 31 in higher yield. Conformational properties of 31 were studied by VT⁻¹ H NMR experiments in two different deuterated solvents. Alkyl ether derivatives (41a-41b ) of 31 , and also tert -butylcalix[4]naphthalene-1,3-crown 42 were synthesized, and all compounds were shown by NMR experiments to exist in cone conformations. -- A synthetic route toward the synthesis of the C₂ᵥ -symmetrical C-12 endo calix[4]naphthalenes e.g., 35 allowed us to evaluate the efficiency of the Suzuki-Miyaura coupling reactions for various benzylic halides and bromomethylnaphthalenes with phenyl- and naphthylboronic acids. Directed ortho Metallation (DoM) reactions using both n -butyl- and tert -butyllithium were evaluated for the introduction of various functional groups orthoto the hydroxyl group of 2-naphthol, bis(2-hydroxy-1-naphthyl)methane and their derivatives. -- Synthesis of calix[4]naphthalene (35 ) was achieved using both acid- and base-induced condensation reactions of compound 98 and aqueous formaldehyde solution. Various alkyl ether derivatives ( 113a-113d ) of 35 were obtained, and their conformational properties were studied by NMR experiments. The X-ray crystal structure of113d revealed that it exists in a cone conformation as a clathrate containing two molecules of toluene located in its hydrophobic cavity. -- Calix[4]naphthalene (114 ), an example of an endo/exo -type calixnaphthalene was synthesized using + Bohmer condensation conditions. Considerable effort was expended to synthesize endo calix[4]naphthalenes (78-80 ), and other calixarenes containing mixed benzene and naphthalene units (e.g., 116 ) via + and/or 3 + 1 Bohmer conditions. Other unsuccessful attempts were made to synthesize all the possible isomers of endo calix[4]naphthalenes (35a-c and 107 ) using Suzuki-Miyaura coupling reactions. -- Several approaches towards modifying the lower rim of calixarenes were undertaken in order to deepen their cavities. The hydroxyl groups of 2 were derivatived to triflates 118-121 and also to nonaflate 125 in order to evaluate Suzuki Miyaura, Stille and Pd-catalyzed carbonylative reaction conditions. The first successful syntheses aryl ether derivatives (131-134 and 137-143 ) of 2 were achieved using either Nucleophilic Aromatic Substitution (SN Ar) or Ullmann ether conditions.
[Epidemiology of contact dermatitis in Marseilles (author's transl)]. (1978)

Five hundred subjects were patch-tested on the one hand with 25 allergens standard group and on the other hand with selected allergens depending on the occupation and history of each patient. They systematic standard series are responsible for 79 p. 100 of contact allergens. Among them the most frequent sensitizers observed include potassium dichromate, nickel sulfate, cobalt chloride, paraphenylenediamine, propylene-glycol, triethanolamine, balsam of Peru. The selected allergens stand for 21 p. 100 of our cases. These results are compared with those of other countries. The main sensitizers are involved in every case. However a few discrepancies are to be noted: turpentine and mercury do not occupy with us a foremost rank, whereas prophylene-glycol and triethanolamine which, according to our statistics, stand fourth and seventh, are not mentioned elsewhere. Differents factors can partly account for these variations: industrial products are submitted to local influence, as it occurs with turpentine for instance, environmental factors play an important part too and, above all, local industries. Nevertheless, this study brings into relief two facts:--the interesting use of systematic standard series, constantly updated, since they are responsible for 79 p. 100 of contact allergens;--the incidence of each patient's history and occupation on the choice of selected allergens, thanks to which we can put into relief less usual causes, though they should not been overlooked, since they stand for 21 p. 100 of the allergens so far listed.
Low-Salinity Polymer Flooding: Improving Polymer Flooding Technical Feasibility and Economics by Using Low-Salinity Make-up Brine (2014)

Abstract Polymer flooding is a mature EOR technique, which is successfully applied in both sandstone and carbonate reservoirs. In ongoing polymer projects, make-up brine is either formation water, sea water or any available water sources like deep or shallow aquifers. In this paper we focus on the use of low salinity water as the make-up brine. The objectives of combining low salinity flooding (LSF) with polymer flooding are three-fold:Using low salinity brine reduces the amount of polymer required to obtain the target viscosity, which may lead to significant cost reduction.Combining the benefit of low salinity flooding with polymer flooding leads to higher oil recovery over conventional polymer flooding.Enhancing the elasticity of polymers by using low salinity brine which may lead to reduced Sorw and increased oil recovery. In addition to the objectives mentioned above, the use of a low-salinity make-up brine can give other benefits, such as better polymer stability (especially at high temperatures), lower sensitivity to polymer shear degradation, lower polymer adsorption and lower scaling and souring tendency. The paper will presentExperimental procedures for investigating the potential benefits of low salinity polymer on both the required polymer concentration and the oil recovery.Experimental results for several field casesDe-risking activities that were undertaken to mitigate any potential negative impact of using low salinity polymer, in the areas of clay swelling, polymer shear sensitivity, mixing and adsorption. The paper concludes that low-salinity polymer flooding can significantly improve existing and anticipated polymer flooding projects by reducing polymer volumes and/or increasing oil recovery. Low-salinity polymer flooding provides opportunities to apply polymer flooding in high-salinity and high-temperature reservoirs, for which polymer flooding with produced or formation water would be technically unfeasible or uneconomic.
Initiative to streamline clinical trials (ISCT): Guidance for academic investigators/sponsors. (2016)

219 Background: The 2011 Canadian Cancer Research Alliance (CCRA) report on the State of Cancer Clinical Trials in Canada outlined in detail the threats to the conduct of academic oncology clinical trials caused by increasing complexity and workload resulting from a perceived onerous regulatory environment. The report recommended engaging Health Canada and key stakeholders to foster agreement in appropriate interpretations of the Canadian Food and Drug Regulations Part C Division 5 and ICH Good Clinical Practice (GCP) guidelines. Methods: The ISCT Working Group (ISCT WG) was formed in 2012 to address the CCRA recommendations for academic clinical trials and include experts from multiple therapeutic areas. The primary objective of the ISCT is to develop specific, practical interpretations of current regulations, laws and guidelines to facilitate Canadian clinical trials. Feedback was obtained from interested parties and ISCT members by means of surveys, face-to-face meetings and conference calls. Results: The major areas of concern identified include Health Canada Clinical Trial Applications, Investigational Product supply, monitoring, oversight of equipment and facilities, delegation of duties, validation of electronic systems, source documents and records retention, trial costs, the consistency of interpretation by different divisions of Health Canada, and access to related resources. A subcommittee was established for each area identified above and a series of recommendations to streamline processes with a focus to reduce regulatory burden for academic clinical trials. The ISCT WG used other relevant documents including the OECD framework and FDA Guidance on Risk Based Monitoring to inform its work. Conclusions: The final recommendations of the ISCT have been provided to all stakeholders, presented at international conferences and published on the N2 website. Canadian academic sites have used guidelines during Health Canada inspections with success. Future goals include an ISCT Workshop for academic site leaders to facilitate implementation of the ISCT guidelines, continue to address areas of concern, and track the success of the recommendations in ameliorating the conduct of academic trials.
Translational R&D insights for the allogeneic CAR T cell therapy field and beyond (2021)

<div class="authors authors-lg"><div class="author"><div class="author-img"><img src="https://cdn.insights.bio/uploads/Sasu_Headshot.png" data-image="1"></div><div class="author-det"> <b>Barbra Sasu, PhD</b>, is the Chief Scientific Officer of Allogene. Barbra joined Allogene as Chief Scientific Officer in April 2018 when the company acquired the allogeneic cell therapy assets from Pfizer. Barbra received a PhD from the Paterson Institute for Cancer Research in Manchester, UK, in the laboratory of T. Michael Dexter, FRS. She conducted postdoctoral research at Harvard Medical School in the laboratory of T. Keith Blackwell, MD, PhD. Barbra joined Amgen in 2001 to work on normal and malignant hematology initially and later expanded her focus to include immune-oncology with an emphasis on T-cell redirective therapies, specifically BiTE molecules. In 2013, she joined Pfizer to become involved with large molecule immuno-oncology including the Pfizer T-cell redirection programs and led diligence to look for a CAR T collaboration partner. This collaboration search resulted in the Cellectis partnership in 2014 and the collaboration with Servier for clinical execution of UCART19 and other preclinical assets. </div></div></div>
Bioengineered embryoids mimic post-implantation development in vitro (2021)

The difficulty of studying post-implantation development in mammals has sparked a flurry of activity to develop in vitro models, termed embryoids, based on self-organizing pluripotent stem cells. Previous approaches to derive embryoids either lack the physiological morphology and signaling interactions, or are not yet optimal for modeling post-gastrulation development. Here, we report a bioengineering-inspired approach aimed at addressing this gap. A high-throughput cell aggregation approach was employed to simultaneously coax mouse embryonic stem cells (ESCs) into hundreds of uniform epiblast-like (EPI) aggregates in a solid matrix-free manner. When co-cultured with mouse trophoblast stem cell (TSC) aggregates, the resulting hybrid structures initiate gastrulation-like events and undergo axial morphogenesis to yield structures, termed EpiTS embryoids , with a pronounced anterior development, including brain-like regions. We identify the presence of an epithelium in EPI aggregates as the major determinant for the axial morphogenesis and anterior development seen in EpiTS embryoids . Our results demonstrate the potential of EpiTS embryoids to study peri-gastrulation development in vitro .
The magnetic ledger-card computer (1958)

Business and government have a need for mechanization of record-keeping and accounting. Both big business organizations and government organizations seem to be approaching a solution to this problem by means of largescale computing equipment and largescale random-access electronic memory devices.
Alpha 1A- and alpha 1B-adrenoceptor-mediated positive chronotropic effects on isolated rat atrium. (1993)

The positive chronotropic effect of alpha 1-adrenoceptor subtypes was studied on the isolated right atrium of adult male Wistar rats. In the presence of beta-blocker propranolol, chloroethylclonidine (Chl) (an irreversible alpha 1B inactivator) reduced the positive chronotropic effect of phenylephrine (Phe). When the basal rate was lowered by cholinergic stimulation. Chl showed less effect on the increase of spontaneous beat rate. H-7, a protein kinase C (PKC) inhibitor, lowered the chronotropic effect to Phe under physiological condition, but did not affect the Phe-induced positive chronotropic effect when basal rate was lessened by carbachol. These suggested that the chronotropic effect was mainly mediated by alpha 1B receptors, and partially related to the activation of PKC by second messengers under physiological conditions. The compensatory effect of the alpha 1-adrenoceptors was mainly mediated by alpha 1A receptors, which is scarcely involved in the activation of PKC.
A simulation model for propagation of partial discharge pulses in transformers (2002)

Partial discharge (PD) measurement is widely accepted as a quality control test for power transformers due to its ability to detect incipient insulation faults. For further development of PD testing as a diagnostic tool, it is important to study the propagation of PD pulses in transformers. A general simulation model is necessary which should include the different construction of transformer windings. In this paper, a simulation model is introduced which is constructed in the frequency domain and which takes account of the frequency dependent characteristics of transformer windings. A description of parameter calculation methods and system solutions is given. Some simulation results are presented. The promising application of this model in the simulation study of PD's in power transformers is outlined.
In Situ Oil Separation and Collection from Water under Surface Wave Condition (2021)

Removal of oil from water is strongly desired due to environmental pollution, and related studies are mainly limited to the material itself. Here, we propose an oil-water separation device, called a floating well, which includes a container for oil collection and a modified mesh screen for oil separation. The mesh screen is superhydrophilic to oil and superhydrophobic to water. The oil removal experiment was performed in a basin. Under the calm surface condition, the oil collection efficiency is shown to be 42-69%. The inadequate oil collection is explained by the breakdown of a thin oil film above water to form an oil-free area, preventing direct contact between the separator and the oil. Sustained by a wave generator, we are surprised to find that with a low-frequency surface wave, the oil collection efficiency is increased to 98%, and the collection speed reaches 2.5 times that under the calm surface condition. The almost complete collection is due to the sustained contact between the separator and the oil, under which the surface wave continuously drives the oil film toward the separator from elsewhere, thus the oil-free area cannot be formed. Our work presents a new clue for large-scale in situ applications, in which the nature wave energy of river/sea can be the driving force for continuous oil separation and collection.
A multiqueue service room MAC protocol for wireless networks with multipacket reception (2003)

An adaptive medium-access control (MAC) protocol for heterogeneous networks with finite populations is proposed. Referred to as the multiqueue service room (MQSR) protocol, this scheme is capable of handling users with different quality-of-service (QoS) constraints. By exploiting the multipacket reception (MPR) capability, the MQSR protocol adaptively grants access to the MPR channel to a number of users such that the expected number of successfully received packets is maximized in each slot. The optimal access protocol avoids unnecessary empty slots for light traffic and excessive collisions for heavy traffic. It has superior throughput and delay performance as compared to, for example, the slotted ALOHA with optimal retransmission probability. This protocol can be applied to random-access networks with multimedia traffic.
Investigation of Device and Electronic Interactions in GaAs Device Processing. (1984)

Abstract : Our Investigation of Defects and Electronic Interactions Associated with GaAs Device Processing has been designed as a three year program with first year tasks focussing on the effects of thermal annealing. During this one year period (August 15, 1983 - August 14, 1984) we have modified the design of the annealing ampul in order to achieve stoichiometry controlled annealing conditions and we have completed the construction of the ultra-high purity annealing apparatus (cosponsored by a grant from (Microgravity Research Associates). Our study of as-grown and annealed GaAs crystals has led to the identification of new defect related midgap levels. We have also discovered that defect interactions in a critical temperature range 800 C to 900 C are controlled by stoichiometry and by the Fermi Energy. We have initiated a collaborative study with Avionics Laboratory of the Wright Patterson Base on ion implantation and defect characterization by the photoluminescence technique. The results of our activity are contained in this report.