gebhart/patrepeval huggingface dataset:
Early diagnosis and successful treatment of acute antibody-mediated rejection of a renal transplant. (2008)

Antibody-mediated rejection is a delicate situation. It rarely occurs but when it does, it usually results in graft dysfunction and frequently, graft loss. There has been no standard protocol for treating antibody-mediated rejection, although several therapeutic protocols have been recommended. Early detection and treatments of suspected antibody-mediated rejection can secure the graft and improve its function. Here, we describe a typical case of antibody-mediated rejection in a 46-year-old woman who was successfully treated with intravenous immunoglobulin, plasmapheresis, and the anti-CD20 monoclonal antibody, rituximab.
Block copolymer self-assembly in ionic liquids (2018)

Ionic liquids (ILs), solely composed of cations and anions, are regarded as a novel class of promising liquids, potentially applicable to energy devices, reaction media, separation materials, etc. ILs have also attracted great attention as new media for molecular self-assembly, capable of producing novel soft materials with unique features never observed for conventional soft materials containing organic and aqueous solvents. In this review, we focus on recent developments in block copolymer (BCP) self-assembly in ILs. Self-assembled structures formed by dilute and concentrated BCP solutions in ILs are discussed in detail. Ion gels formed by BCP self-assembly have received special interest because they exhibit excellent physical properties of tunable viscoelasticity and solution processability without impairing the intrinsic properties of ILs, such as nonvolatility, nonflammability, and high ionic conductivity. Applications of ion gels based on BCP self-assembly for electric double layer capacitors, lithium-ion batteries, and electroactive soft actuators are also addressed.
Near-Infrared Self-Powered Linearly Polarized Photodetection and Digital Incoherent Holography Using WSe2/ReSe2 van der Waals Heterostructure (2021)

Polarization-sensitive photodetection has attracted considerable attention as an emerging technology for future optoelectronic applications such as three-dimensional (3D) imaging, quantum optics, and encryption. However, traditional photodetectors based on Si or III-V InGaAs semiconductors cannot directly detect polarized light without additional optical components. Herein, we demonstrate a self-powered linear-polarization-sensitive near-infrared (NIR) photodetector using a two-dimensional WSe<sub>2</sub>/ReSe<sub>2</sub> van der Waals heterostructure. The WSe<sub>2</sub>/ReSe<sub>2</sub> heterojunction photodiode with semivertical geometry exhibits excellent performance: an ideality factor of 1.67, a broad spectral photoresponse of 405-980 nm with a significant photovoltaic effect, outstanding linearity with a linear dynamic range wider than 100 dB, and rapid photoswitching behavior with a cutoff frequency up to 100 kHz. Strongly polarized excitonic transitions around the band edge in ReSe<sub>2</sub> lead to significant 980 nm NIR linear-polarization-dependent photocurrent. This linear polarization sensitivity remains stable even after exposure to air for longer than five months. Furthermore, by leveraging the NIR (980 nm)-selective linear polarization detection of this photodiode under photovoltaic operation, we demonstrate digital incoherent holographic 3D imaging.
The EPC Sensor Network for RFID and WSN Integration Infrastructure (2007)

Despite the popularity of current Radio Frequency Identification (RFID) and Wireless Sensor Networks (WSN), current research fails to propose the global vision that is needed for truly pervasive computing. In this paper we introduce our effort to build a global standard infrastructure for WSN and RFID based on the EPCglobal standard Architecture Framework. By leveraging the EPC Network infrastructure, our proposed EPC Sensor Network will effectively provide standardized WSN/RFID integration framework to support sensor data sharing.
A robust stripe segmentation method for 3D measurement of structured light (2015)

Ambient noise and variation of illumination intensity can severely degrade the performance of the structured light sensor. To overcome these noises, we present a robust algorithm based on adaptive monochromatic space and minimum entropy model for the laser stripe segmentation in the structured light image. The proposed method not only makes high accuracy segmentation of the laser stripe, but also keeps the smoothness of the stripe. Experimental results show that the algorithm has great improvement to four classical algorithms.
RADIATION DOSES DURING CT FLUOROSCOPY (2000)

CT fluoroscopy (CTF) is a relatively new imaging modality that is particularly useful for performing complex biopsy procedures. Despite the obvious benefits, the potential exists to deliver considerable radiation doses to both the patients and medical staff. The purpose of our study was to quantify the radiation levels based upon typical clinical procedures. To assess the potential radiation risks, the patient radiation doses via the CT dose index (CTDI) method were measured during CTF for a GE Pro-Speed CT scanner using standardized head and body phantoms and a CT ionization chamber. The measurements were performed for a variety of kVp, mA, and slice thickness settings. To determine patient radiation doses, the CT kVp, mA, and total CTF scan times were recorded for various biopsy procedures. To determine the radiation doses to the hands of the radiologists, a radiation survey meter was used to measure the scattered radiation from standard phantoms. The effectiveness of various types of leaded gloves and shields were also determined. The measured CTDI values ranged from 20.4 cGy min(-1) to 63.1 cGy min(-1) of CTF. For a group of 78 patients, the clinically utilized imaging times varied from 13.0 to 407 s with an mean time of 96.6 s +/- 78.9 s (1 standard deviation). The scattered x-ray radiation at the position of the radiologists hands performing the biopsy procedures was measured to be 0.6 to 1.5 mGy min(-1). The thin leaded gloves provided a relatively minimal reduction in the scattered radiation to the hands between 11% and 44% dependent upon the kVp and the type of glove. However, floor mounted radiation shields reduced the scattered radiation levels to the body by 94% to 99%. In comparison to standard x-ray fluoroscopy, CTF employs much higher radiation dose rates due to the higher kVp, mA, and rotating geometry. It is important to minimize the radiation dose to patients and staff by limiting the imaging times, employing lower mA settings, and using appropriate radiation protection measures.
Upregulation of Complement Regulators MCP (CD46), DAF (CD55) and Protectin (CD59) in Arthritic Joint Disease (1994)

CD46, CD55 and CD59 are cell surface glycoproteins which are widely distributed on normal tissue, where they function in the prevention of complement-mediated damage. In this study we have investigated the altered expression of these molecules under inflammatory conditions both in vitro and in vivo. By using immunocytochemical techniques we demonstrated marked but disparate upregulation of these molecules in IL1-treated cartilage and in diseased cartilage from arthritic joints compared to normal cartilage in both humans and pigs. Expression of these proteins was restricted to the chondrocyte surface, and was also demonstrated on isolated chondrocytes grown in monolayer culture and stimulated with IL1. It is suggested that the elevated levels of these regulatory proteins may be necessary to ameliorate the multiple damaging effects of the inflammatory processes associated with destructive joint diseases.
Regulation of replicative senescence by insulin‐like growth factor‐binding protein 3 in human umbilical vein endothelial cells (2007)

Insulin/insulin-like growth factor (IGF) signaling pathways are among the most conserved processes in aging in organisms ranging from yeast to mammals. Previously, using cDNA microarray technology, we reported that expression of IGF-binding protein 3 (IGFBP3), one of the IGF-binding proteins, was increased with age in human dermal fibroblasts. In this study, the role of IGFBP3 on cellular senescence was studied in human umbilical vein endothelial cells (HUVEC). The expression levels of IGFBP3 mRNA and protein were increased in HUVECs with age. Knockdown of IGFBP3 in old cells with IGFBP3 short hairpin RNA (shRNA) retrovirus resulted in the partial reduction of a variety of senescent phenotypes, such as changes in cell morphology, and decreases in population doubling times and senescence-associated beta-galactosidase (SA-beta-gal) staining. Down-regulation of IGFBP3 rescued the growth arrest induced by p53 overexpression in young HUVECs. In contrast, up-regulation of IGFBP3 in young cells and prolonged IGFBP3 treatment accelerated cellular senescence, confirmed by cell proliferation and SA-beta-gal staining. The FOXO3a (forkhead box O3a) protein level was increased in old IGFBP3 shRNA cells. The treatment of young HUVECs with IGFBP3 repressed the levels of FOXO3a protein. Furthermore, calorie restriction reduced IGFBP3 protein levels, which were found to be increased with age in the rat liver and serum. These results suggest that IGFBP3 might play an important role in the cellular senescence of HUVECs as well as in vivo aging.
Redefining the TGR5 Triterpenoid Binding Pocket at the C‐3 Position (2010)

A defining characteristic: Syntheses of potent TGR5 agonists were used to characterize binding interactions. A serie of C-3 modified betulinic acid derivatives were synthesized and evaluated. Among them, epoxide 15 showed nanomolar activity. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Duality and classification of bilinear time-frequency signal representations (1991)

The author discusses a fundamental duality principle of BTFRs (bilinear time-frequency representations) and presents a systematic classification of BTFRs which is consistent with BTFR duality. BTFRs are first grouped into two basic domains, namely, the energy density domain (E-domain) with energetic interpretation, and the correlation domain (C-domain) with correlative interpretation. It is shown that these domains are related by a Fourier transform duality: to any BTFR, BTFR relation, or BTFR property of the E-domain, there corresponds a dual BTFR, BTFR relation, or BTFR properties of the C-domain, and vice versa. With this duality principle as a background, a classification of BTFRs is given. This classification is based on two dual shift-invariance properties and a self-dual scale-invariance property of BTFRs. The mathematical description of BTFRs by means of kernel functions is simplified, inside the respective BTFR classes. It is shown that BTFRs which are both shift and scale invariant can be represented as superpositions of generalized Wigner distributions (E-domain) or generalized ambiguity function (C-domain).< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Magnetic Particles Coupled to Disposable Screen Printed Transducers for Electrochemical Biosensing (2016)

Ultrasensitive biosensing is currently a growing demand that has led to the development of numerous strategies for signal amplification. In this context, the unique properties of magnetic particles; both of nano- and micro-size dimensions; have proved to be promising materials to be coupled with disposable electrodes for the design of cost-effective electrochemical affinity biosensing platforms. This review addresses, through discussion of selected examples, the way that nano- and micro-magnetic particles (MNPs and MMPs; respectively) have contributed significantly to the development of electrochemical affinity biosensors, including immuno-, DNA, aptamer and other affinity modes. Different aspects such as type of magnetic particles, assay formats, detection techniques, sensitivity, applicability and other relevant characteristics are discussed. Research opportunities and future development trends in this field are also considered.
Descrizione dei testi costituenti il fondo Pullé dell’Archiginnasio (2007)

Descrizione dettagliata delle opere costituenti il "Fondo Pullé" dell'Archiginnasio, con particolare attenzione per i manoscritti indiani, tanto per quelli preservati mediante riproduzione fotografica quanto, e soprattutto, per quelli conservati in originale.
Enhanced detection sensitivity of “fluorescence reduction” by shifting the analyte absorbance spectrum and use of a fluorescent paper with higher signal/noise ratio (1998)

Nonfluorescing protein bands can be detected by the fluorescence optics of the commercial gel electrophoresis apparatus with automated scanning of the migration path (HPGE-1000, LabIntelligence, Belmont CA), taking advantage of the decrease of emission from a fluorescent paper placed below the gel by the absorbance of proteins ("fluorescence reduction"). That decrease of fluorescence gives rise to an inverted protein peak. Nonfluorescent colorless proteins appear to reduce the intensity of light emitted from the fluorescent paper due to absorbance of incident and emitted light. When the absorbance spectrum only slightly overlaps with the excitation and emission spectra of the fluorescent paper, that reduction is weak, and detection sensitivity in that application is consequently only 1/30 of that of fluorescent proteins. By contrast, when the protein is colored so that its absorbance spectrum overlaps widely with the excitation and emission spectra of the fluorescent paper, the sensitivity of "fluorescence reduction" equals 1/4 to 1/5 of that obtained for fluorescent proteins. Bands detected by "fluorescence reduction" provide a quantitative measure of protein load and mobility. The area of the inverted bands is proportional to protein loads up to 16 microg/lane of the gel tray. A theory of "fluorescence reduction" is presented which accounts for the existence of a linear relationship between band area and load.
ChemInform Abstract: Uridine Phosphorylase Inhibitors: Chemical Modification of Benzyloxybenzyl‐barbituric Acid and Its Effects on UrdPase Inhibition. (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Truncated Parabolic-Index Fiber with Minimum Mode Dispersion (1978)

The use of a parabolic-index fiber as an optical transmission line has been receiving extensive attention because of its excellent mode dispersion characteristics. In the present paper, the modal dispersion in the optical fiber with truncated parabolic index distribution is analyzed theoretically in detail by using a variational method. Taking the influence of the cladding upon the propagating modes into consideration, it is found that there exists an optimum index distribution for which the modal dispersion is minimized. The standard deviation of the normalized group delay of propagating modes is used to estimate the modal dispersion behavior of the fiber.
A Patient-specific Preplanning Treatment Algorithm for Focused Ultrasound Therapy of Spinal Cord Injury (2023)

Focused ultrasound (FUS) is an increasingly prevalent therapeutic tool used in medicine to treat patients non-invasively, cost-effectively, and without any ionizing radiation. Depending on the clinical application, therapeutic ultrasound can be used for tissue ablation, physiotherapy, lithotripsy, and drug delivery, among other therapies. For the treatment to be effective, it is important to understand the acoustic pressure profile in the tissue to ensure the focal point intensity is sufficient to achieve therapy without damaging the tissue. In spinal cord injury (SCI), where FUS is hypothesized to promote blood flow to the site of injury to facilitate healing, it can be difficult to predict the expected pressure wavefields in real-time. This challenge is due to the complex structure of the spinal cord and variations in acoustic properties within the field of view, leading to distortion of the ultrasound wave front. To address this issue, we present an automated approach to visualize beam propagation and acoustic pressure distribution to aid with placement of the FUS probe. By simulating propagation of the ultrasound beams through patient-specific Digital Imaging and Communications in Medicine (DICOM) images, therapy can be optimized to minimize tissue damage while providing adequate focusing and focal intensity. In this study, porcine spinal cord images acquired after acute SCI are used to determine optimal FUS transducer placement.
Liquid anion membrane electrodes sensitive to metal cation concentration (1970)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLiquid anion membrane electrodes sensitive to metal cation concentrationGiancarlo. Scibona, Leda. Mantella, and Pier R. DanesiCite this: Anal. Chem. 1970, 42, 8, 844–848Publication Date (Print):July 1, 1970Publication History Published online1 May 2002Published inissue 1 July 1970https://pubs.acs.org/doi/10.1021/ac60290a011https://doi.org/10.1021/ac60290a011research-articleACS PublicationsRequest reuse permissionsArticle Views37Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The impact of fouling on performance evaluation of evaporative coolers and condensers (2005)

Fouling of evaporative cooler and condenser tubes is one of the most important factors affecting their thermal performance, which reduces effectiveness and heat transfer capability with time. In this paper, the experimental data on fouling reported in the literature are used to develop a fouling model for this class of heat exchangers. The model predicts the decrease in heat transfer rate with the growth of fouling. A detailed model of evaporative coolers and condensers, in conjunction with the fouling model, is used to study the effect of fouling on the thermal performance of these heat exchangers at different air inlet wet bulb temperatures. The results demonstrate that fouling of tubes reduces gains in performance resulting from decreasing values of air inlet wet bulb temperature. It is found that the maximum decrease in effectiveness due to fouling is about 55 and 78% for the evaporative coolers and condensers, respectively, investigated in this study. For the evaporative cooler, the value of process fluid outlet temperature Tp,out varies by 0.66% only at the clean condition for the ambient wet bulb temperatures considered. Copyright © 2005 John Wiley & Sons, Ltd.
Freeform Optics Enabling Optics in Three Dimensions (2013)

Freeform optical surfaces are emerging as a path to truly three dimensional optical designs. Here, the status of optical design, fabrication, and testing of three dimensional optical systems with freeform surfaces will be presented.
EXTRACTION OF PHYSIOLOGICAL PARAMETERS USING AUDIO SIGNALS (2014)

It is observed by the study that audio recordings of sustained vowels may determine the breath, whether a person’s pulse is high or low. However, good results for HR and SC values always required a speaker’s training input, which limits spontaneous recognition as well as analysis of audio recordings without physiological reference data in possible applications. To improve the performance, it is aimed to increase recognition accuracy by selection of features, and to compare the importance of different feature groups. Recognition accuracy could be further increased by enlargement of the data set and development of a predictor able to recognize predictions out of an expected range of values. It has also been observed that a threshold for separation of high pulse and low pulse of HR is required and has been taken from the user input. However, this should be computed from the speech signal automatically by combining the speech signal frequency and amplitude values. In the presented work, a self adaptive threshold selection is proposed based on the input speech signal amplitude, speed and frequency. Further a better correlation is established between the speech signal level ad HR and skin conductance.
Purification, cloning, and sequence of outer membrane protein P1 of Haemophilus influenzae type b (1988)

Outer membrane protein P1 from Haemophilus influenzae type b MinnA was purified and partially characterized. Antiserum was generated against the purified protein and was used to immunologically screen a lamba EMBL3 genomic library prepared from strain MinnA DNA. A 4.2-kilobase-pair EcoRI-BamHI fragment containing the P1 gene was subcloned into pBR322. The recombinant protein was synthesized by Escherichia coli K-12, in which it localized to the outer membrane. The N-terminal sequence of the purified protein was determined and found to correspond to residues 23 through 36. The 22-amino-acid leader peptide had a typical structure, with two lysine residues near the amino terminus, a stretch of hydrophobic residues, and alanine residues at positions 20 and 22. The Mr of the processed protein was 47,752, which is in good agreement with the estimate of 50,000 from sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Putative -35 and -10 promoter sequences were identified upstream from the translational start site. Codon usage was examined and determined to be substantially different than the codon preference in E. coli.