gebhart/patrepeval huggingface dataset:
Comparison of the RpoH-Dependent Regulon and General Stress Response in Neisseria gonorrhoeae (2006)

In the gammaproteobacteria the RpoH regulon is often equated with the stress response, as the regulon contains many of the genes that encode what have been termed heat shock proteins that deal with the presence of damaged proteins. However, the betaproteobacteria primarily utilize the HrcA repressor protein to control genes involved in the stress response. We used genome-wide transcriptional profiling to compare the RpoH regulon and stress response of Neisseria gonorrhoeae, a member of the betaproteobacteria. To identify the members of the RpoH regulon, a plasmid-borne copy of the rpoH gene was overexpressed during exponential-phase growth at 37 degrees C. This resulted in increased expression of 12 genes, many of which encode proteins that are involved in the stress response in other species. The putative promoter regions of many of these up-regulated genes contain a consensus RpoH binding site similar to that of Escherichia coli. Thus, it appears that unlike other members of the betaproteobacteria, N. gonorrhoeae utilizes RpoH, and not an HrcA homolog, to regulate the stress response. In N. gonorrhoeae exposed to 42 degrees C for 10 min, we observed a much broader transcriptional response involving 37 differentially expressed genes. Genes that are apparently not part of the RpoH regulon showed increased transcription during heat shock. A total of 13 genes were also down-regulated. From these results we concluded that although RpoH acts as the major regulator of protein homeostasis, N. gonorrhoeae has additional means of responding to temperature stress.
Device performance and optimization for 5th- and 6th-generation microprocessors (1997)

A family of CMOS processing technologies used to produce AMDs fifth and sixth generation microprocessors (K5 and K6) is described. Some of the issues that arose during the technology development and the transfer to manufacturing are also presented. Transistor performance is compared to literature results and shown to be best in its class.
Low specific on-resistance 400V LDMOST (1981)

A readily integratable high voltage lateral DMOS (LDMOST) has been developed which has both as low or lower specific on-resistance and lower input capacitance as compared to the same breakdown voltage vertical transistors. The LDMOST has been designed for a reverse breakdown voltage V <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">DSS</inf> = 400V. The active area of the device is 2 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> and the drift region length is 26µm. The value of R <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">on</inf> A for this transistor is 5.6Ω mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> (R <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">on</inf> = 2.8Ω). The fabrication technology is compatible with that used for bipolar and MOS IC fabrication.
ChemInform Abstract: SYNTH. EINES ACTINOMYCIN‐ANALOGEN MIT SUBSTITUIERTEN LACTON‐SAUERSTOFFATOMEN, (1′,1′‐BIS‐(L‐ALPHA,BETA‐DIAMINOPROPIONSAEURE))‐ACTINOMYCIN D(C1) (I) (1972)

Abstract Die Synthese von (I), eines Lactam‐Analogen von Actinomycin D, wird beschrieben.
MSX1-expression during the different phases in healthy human endometrium (2023)

Abstract Purpose: The human endometrium consists of different layers (basalis and functionalis) and undergoes different phases throughout the menstrual cycle. In a former paper our research group was able to describe MSX1 as a positive prognosticator in endometrial carcinomas. The aim of this study was to examine the MSX1 expression in healthy endometrial tissue throughout the different phases to gain more insight on the mechanics of MSX-regulation in the female reproductive system. Materials and Methods: In this retrospective study we investigated a total of 19 normal endometrial tissues (7 during proliferative phase and each 6 during early and late secretory phase). We used immunohistochemical staining and an immunoreactive score (IRS) to evaluate MSX1 expression. We also investigated correlations with other proteins, that have already been examined in our research group using the same patient collective. Results: MSX1 is highly expressed during the proliferative phase and downregulated at early and late secretory phase (p=0.018). Also, a positive correlation between MSX1 and the progesterone-receptor A (PR-A) (correlation coefficient (cc)=0.0671; p=0.024), the progesterone receptor B (PR-B) (cc=0.0691; p=0.018) was found. A trend towards negative correlation was recognized between MSX1 and Inhibin Beta-C-expression in glandular cells (cc=-0.583; p-value=0.060). Conclusion: MSX1 is known as a member of the muscle segment homeobox gene family. MSX1 is a p53-interacting protein and overexpression of homeobox MSX1 induced apoptosis of cancer cells. Here we show that MSX1 is highly expressed especially in the proliferative phase of glandular epithelial tissue of the normal endometrium. Because MSX1 is known to be downregulated by progesterone, the found correlation of MSX1 and both PR-A and -B may represent a direct regulation of the MSX1 gene by a PR-response element.
Prediction of patient‐specific risk of early preterm delivery using maternal history and sonographic measurement of cervical length: a population‐based prospective study (2006)

This study provides a model that can give an accurate patient-specific risk of preterm delivery. The detection rate of screening by a combination of maternal factors and the measurement of cervical length was substantially higher than that of screening by each method alone.
Highly Stereoselective Aldol Reaction Based on Titanium Enolates from (S)-1-Benzyloxy-2-methyl-3-pentanone (2005)

Alternative titanium-mediated aldol procedures based on several protected beta-hydroxy ethyl ketones have been surveyed. Eventually, enolization of (S)-1-benzyloxy-2-methyl-3-pentanone (1) with (i-PrO)TiCl3/i-Pr2NEt provided a very reactive enolate that afforded the corresponding 2,4-syn-4,5-syn aldol adducts in high yields and diastereomeric ratios with a broad range of aldehydes.
Hydrogen bonds in “push-pull” enamines (2004)

A comparison of hydrogen bond strengths in various enamines was made by monitoring the differential shifts Δδ(X) as the difference of NMR chemical shifts between E and Z forms of the nuclei directly involved in hydrogen bonding, i.e., X = 15N, 1H, 17O atoms. The interpretation of these differential values was aided by ab initio calculations and X-ray derived geometric parameters for selected compounds. It is shown that Δδ(N1H) and Δδ(15N) give conclusive results and their changes are rationally interpreted by invoking established contributing effects that influence the values of chemical shifts. The Δδ(17O) parameter is sensitive to intramolecular geometry, mainly bond angles around oxygen and co-planarity of the atoms forming the hydrogen bonds. The latter factor is important in determining the strength of hydrogen bonds. Even a weak acceptor such as the lactone function gives a relatively strong hydrogen bond as compared with sp3-hybridized sulfonyl or sulfinyl acceptors. The hybridization of the penultimate atom of an acceptor plays a crucial role in determining the strength of hydrogen bonding.
Reducing detent force and three-phase magnetic paths unbalance of PM linear synchronous motor using modular primary iron-core structure (2014)

The Detent force and unbalance of the three-phase inductances are the major obstacle for permanent magnet linear synchronous motors (PMLSM) obtaining higher positioning accuracy. They both can be attributed to the longitudinal end-effect that, however, is an inherent characteristic for PMLSMs. To overcome these drawbacks, this paper utilizes a reverse perspective: increasing the number of ends. Thus, a modular primary iron-core PM linear synchronous motor (MPI-PMLSM) is investigated. Unlike for conventional linear synchronous motors, the MPI-PMLSM's primary iron-cores are dispersed. This structure allows the MPI-PMLSM very small detent force, and moreover, it almost eliminates the inductances unbalance. The effectiveness is proved by both finite element analysis and experiment.
<title>Comparison between the astronaut and standard operators as telemetry monitor for effects of audio feedback system in the operation of the Engineering Test Satellite VII</title> (2001)

It is the most important that we perform safe and reliable teleoperation of space robots in the experiment/operation using real satellite. Therefore we have developed and used Audio Feedback System (AFS) that use some auditory information such as motorized sound and prerecorded voice converted from a part of telemetry information to reduce loads to operators of space robots of the Engineering Test Satellite VII(ETS-VII). We applied AFS to the experiment ofAntenna Assembling Mechanism (AAM) which is experiment module of the Communications Research Laboratory (CRL) on the ETS-Vil for testing the mechanism of assembling structures in space. Our purpose of this study is to assess effectiveness of AFS by using the Eye Mark Recorder (EMR) which records eye movements for the astronaut and two operators as telemetry monitor who observe telemetry data. In results of macro shape of 0-500 (deg/sec) velocity distribution graph, average fixation time, and average velocity of eye movement, we have got important points as followings: ( 1) the spectrum patterns of velocity of eye movement of specialist operator of controlling space robots like an astronaut are significantly differed from other two operators, (2) the spectrum patterns of velocity of eye movement of specialist operator and nonexpert operator are not affected ofAFS, (3) the spectrum patterns of velocity of eye movement of well-trained expert operator was similar to specialist operator with AFS and similar to nonexpert operators without AFS, (4) average fixation time of specialist operator was not effected by AFS, average fixation time of well-trained expert operator, nonexpert operator became long without AFS support.
Do Boumediene Rights Expire (2012)

In 2008, Guantanamo detainees won a landmark victory in Boumediene v. Bush, which held that the Congress and the President could not prevent the detainees from accessing the courts to seek release via habeas corpus. The Court decided that persons claiming to be innocent civilians deserved a day in court, even though they were noncitizens held by the U.S. military as enemy combatants on foreign territory. The Court applied a fact-specific test that granted habeas rights to noncitizens outside the United States only when a balance of factors — including citizenship, enemy status, the nature of status review procedures, the military and diplomatic situation in the territory of detention, and other practical equities — demanded it. Now, several years later, dozens of detainees have had that day in court and have lost; they have been found to be enemy fighters who can lawfully be detained for the duration of the relevant conflict. Given this new status — no longer presumed innocents but now judicially-confirmed enemy fighters — and the new way that status was determined — habeas corpus in federal courts — does application of the Boumediene test today give them a continued constitutional right to file additional habeas or other future legal claims? This essay raises and provides a framework for evaluating this critical question, a question which will only gain importance over time as the war in Afghanistan winds down and the conflict with Al Qaeda, the Taliban and affiliated groups continues to evolve, prompting detainees to raise new factual and legal challenges to their ongoing detention. In a recent filing, the executive branch signaled that for now it will not contest ongoing court access for the judicially-confirmed enemy fighters at Guantanamo, but this should not end the matter. If, as appears to be the case, Boumediene rights concern subject matter jurisdiction, courts will have a duty to raise the issue sua sponte and the executive will lack legal authority to waive the argument.
Comment and Reply on “Crustal structure from three-dimensional modeling of a metamorphic core complex: A model for uplift, Santa Catalina-Rincon mountains, Arizona” (1987)

Research Article| October 01, 1987 Comment and Reply on “Crustal structure from three-dimensional modeling of a metamorphic core complex: A model for uplift, Santa Catalina-Rincon mountains, Arizona”: COMMENT Carlos L. V. Aiken Carlos L. V. Aiken 1Center for Lithospheric Studies, University of Texas at Dallas, P.O. Box 830688, Richardson, Texas 75083-0688 Search for other works by this author on: GSW Google Scholar Author and Article Information Carlos L. V. Aiken 1Center for Lithospheric Studies, University of Texas at Dallas, P.O. Box 830688, Richardson, Texas 75083-0688 Publisher: Geological Society of America First Online: 02 Jun 2017 Online ISSN: 1943-2682 Print ISSN: 0091-7613 Geological Society of America Geology (1987) 15 (10): 978–979. https://doi.org/10.1130/0091-7613(1987)15<978:CAROCS>2.0.CO;2 Article history First Online: 02 Jun 2017 Cite View This Citation Add to Citation Manager Share Icon Share Facebook Twitter LinkedIn Email Permissions Search Site Citation Carlos L. V. Aiken; Comment and Reply on “Crustal structure from three-dimensional modeling of a metamorphic core complex: A model for uplift, Santa Catalina-Rincon mountains, Arizona”: COMMENT. Geology 1987;; 15 (10): 978–979. doi: https://doi.org/10.1130/0091-7613(1987)15<978:CAROCS>2.0.CO;2 Download citation file: Ris (Zotero) Refmanager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentBy SocietyGeology Search Advanced Search Abstract No Abstract Available. This content is PDF only. Please click on the PDF icon to access. First Page Preview Close Modal You do not have access to this content, please speak to your institutional administrator if you feel you should have access.
A dynamic power management procedure in cognitive radio (2010)

To minimize interference with primary users, one of the major concerns in cognitive radio is to determine the allowable transmission power. This paper addresses the problem of power management to insure on one hand, no interference with primary user and on the other hand, the requested QoS (Quality of Service) level to the secondary transmitter. In this paper we propose a two steps method to determine the transmission power of cognitive transmissions. In the first step “Worst cases power management : WCPM”, we show that, although it's a very quick and preventive method, using this power management procedure leads to a limitation in the range of the cognitive radio network. For this reason, we propose to use a “High Capabilities based Power Allocation and Reallocation: HCPAR”. Which is based on three algorithms “OCAA: Optimized Channel Allocation Algorithm”, “HFPRA: Handoff Free Power Reallocation Algorithm” and “HFPSRA: Handoff Free Power Switching and Reallocation Algorithm”. The results illustrate the effect of the proposed procedure, on increasing the transmission power level of the secondary users as well as the number of served cognitive nodes and on decreasing the number of channel switching (handoffs) for the cognitive transmissions.
9-BBN and chloride catalyzed reduction of chlorophosphines to phosphines and diphosphines (2022)

The commercially available Lewis acid, 9-BBN and Lewis basic [Et<sub>4</sub>N]Cl are used as catalysts for the reduction of chlorophosphines R<sub>2</sub>PCl in the presence of phenylsilane. Aryl-chlorophosphines afford primarily diphosphines (P<sub>2</sub>R<sub>4</sub>) while secondary phosphines predominate for alkyl-substituted precursors. Use of the combined catalysts leads to reduced reaction time and temperature, providing a rapid, scalable, and facile protocol for the preparation of diphosphines or secondary phosphines.
A declarative sensornet architecture (2007)

Increased code reuse, independent development, and in-teroperability are three key missing characteristics of sensor-net programming today that motivate the need for an overall sensornet architecture. Architecture traditionally implies a
Fast Multi-Resolution Exhaustive Search Algorithm Based on Clustering for Efficient Image Retrieval (2001)

In order to achieve optimal retrieval, i.e., to find the best match to a query according to a certain similarity measure, the exhaustive search should be performed literally for all the images in a database. However, the straightforward exhaustive search algorithm is computationally expensive in large image databases. To reduce its heavy computational cost, this paper presents a fast exhaustive multi-resolution search algorithm based on image database clustering. Firstly, the proposed algorithm partitions the whole image data set into a pre-defined number of clusters having similar feature contents. Next, for a given query, it checks the lower bound of distances in each cluster, eliminating disqualified clusters. Then, it only examines the candidates in the remaining clusters. To alleviate unnecessary feature matching operations in the search procedure, the distance inequality property is employed based on a multi-resolution data structure. The proposed algorithm realizes a fast exhaustive multi-resolution search for either the best match or multiple best matches to the query. Using luminance histograms as a feature, we prove that the proposed algorithm guarantees optimal retrieval with high searching speed.
Cholinergic modulation of activity-dependent synaptic plasticity in the piriform cortex and associative memory function in a network biophysical simulation (1995)

The effect of activation of cholinergic receptors on long-term potentiation (LTP) in rat piriform cortex pyramidal cells was studied using extracellular and intracellular recordings in brain slice preparations. The functional role of this modulation was studied in a realistic network biophysical stimulation. Repetitive stimuli were applied in two paradigms: one in which the recorded cell was held at its resting potential and one in which synaptic activity was superimposed on a depolarizing pulse strong enough to evoke four action potentials. In the absence of cholinergic modulation, stimulation at 5 Hz induced LTP primarily in the second condition (13.7%, n = 6 out of 9, measured at 10 min after tetanus). When stimuli were applied in the presence of the muscarinic agonist carbachol (20 microM), LTP of greater amplitude was induced in both paradigms (resting: 41.5%, n = 11 out of 16, depolarized: 36%, n = 5 out of 7, measured at 10 min after tetanus). Increases in excitatory postsynaptic potential (EPSP) amplitudes in the presence of carbachol were gradual, starting at the time 5 Hz stimuli were applied and continuing until an action potential was evoked synaptically. In the presence of the NMDA receptor antagonist 2-amino-5-phosphonovaleric acid (APV), LTP could not be induced. The muscarinic antagonist atropine also prevented LTP induction in the presence of carbachol. Cholinergic modulation of synaptic plasticity was examined in a previously developed realistic biophysical network simulation. In simulations, use of a gradual rate of synaptic modification prevented excessive strengthening of synapses, which could cause interference between stored patterns. The effect of excess synaptic strengthening can be avoided by introducing activity dependent depression of synaptic strength. Coactivation of learning and depression rules results in a stable system where no interference occurs, at any rate of learning. Implementing the depression rule only during recall does not improve the network's performance. This implies that reduction in the strength of synaptic connections should occur in the presence of ACh, more than in normal conditions. We propose that two effects of ACh--enhancement of LTP and enhancement of LTD--should act together to increase the stability of the cortical network in the process of acquiring information.
A novel design for a multistage corona stabilized closing switch (2011)

The possibility of controlling the voltage distribution across the gaps of a closing switch based on a cascade of corona stabilized electrodes has been examined. When operating in a corona stabilized mode the corona current flowing in each gap must be equal. By altering the corona characteristics of the gaps, through changing electrode separation and the area of corona emission, it should therefore be possible to control the voltage distribution across the elements of the cascade. A simple theoretical model of the behavior of corona emission for an electrode with a protruding cylindrical corona generation element has been developed. Experimental tests have confirmed the broad validity of the model. The experimental data for individual electrode geometries has been used to predict the expected self break behavior of a two gap cascade and the predictions are compared with experimental data. The voltage distribution across the cascade has also been measured and compared with the values predicted from the model.
Net emission of Ar–H2–He thermal plasmas at atmospheric pressure (2010)

The net emission coefficient (NEC) has been calculated for Ar–H 2 –He thermal plasmas and for a temperature range from 5000 to 30 000 K. The plasma is supposed to be in local thermodynamic equilibrium at atmospheric pressure. This study takes into account the radiation resulting from the atomic continuum, the molecular continuum and the atomic lines. Particular attention has been paid to the treatment of helium lines broadenings. The results of NECs are presented for pure gases and Ar–H 2 –He mixtures. Radiation is weak in pure helium at low temperatures because of the high ionization energy of this species. Conversely, at very high temperature, the influence of hydrogen tends to decrease because ionic lines do not exist for this last species. Finally, a small proportion of helium in Ar–H 2 mixtures does not change the NEC because of the weak intensity of the helium lines.
Professional quality of life and burnout among medical physicists working in radiation oncology: The role of alexithymia and empathy (2020)

Alexithymic personality trait increased the likelihood to develop burnout, with less professional satisfaction amongst MPs working in radiation oncology. Empathy results in higher professional fulfilment. These results may be used to benchmark preventing strategies, including peer support, debriefing sessions, leadership initiatives and work-load limitation strategies.
Incorporating Isolated Molybdenum (Mo) Atoms into Bilayer Epitaxial Graphene on 4H-SiC(0001) (2013)

The atomic structures and electronic properties of isolated Mo atoms in bilayer epitaxial graphene (BLEG) on 4H-SiC(0001) are investigated by low temperature scanning tunneling microscopy (LT-STM). LT-STM results reveal that isolated Mo dopants prefer to substitute C atoms at α-sites and preferentially locate between the graphene bilayers. First-principles calculations confirm that the embedding of single Mo dopants within BLEG is energetically favorable as compared to monolayer graphene. The calculated band structures show that Mo-incorporated BLEG is n-doped, and each Mo atom introduces a local magnetic moment of 1.81 μB into BLEG. Our findings demonstrate a simple and stable method to incorporate single transition metal dopants into the graphene lattice to tune its electronic and magnetic properties for possible use in graphene spin devices.