gebhart/patrepeval huggingface dataset:
Nucleic Acid-based Detection of Bacterial Pathogens Using Integrated Microfluidic Platform Systems (2009)

The advent of nucleic acid-based pathogen detection methods offers increased sensitivity and specificity over traditional microbiological techniques, driving the development of portable, integrated biosensors. The miniaturization and automation of integrated detection systems presents a significant advantage for rapid, portable field-based testing. In this review, we highlight current developments and directions in nucleic acid-based micro total analysis systems for the detection of bacterial pathogens. Recent progress in the miniaturization of microfluidic processing steps for cell capture, DNA extraction and purification, polymerase chain reaction, and product detection are detailed. Discussions include strategies and challenges for implementation of an integrated portable platform.
Propuesta de reforma en la iglesia del convento de San Pedro de Brozas (Cáceres) por Theodosio de Magalães (2006)

In pre-implant surgery, the autologous bone graft can be harvested from various sites. The tibial diaphysis cortical bone gives a very dense graft which does not resorb. It can be crushed for sinus filling, or used in a monoblock as apposition graft or to repair alveolar cleft sequels. Its availability, its simple and speedy harvesting, and its very low morbidity make it a good choice for most pre-implant reconstructive procedures.
Safe injection techniques (1999)

In this article Barbara Workman describes the correct technique for safe intradermal, subcutaneous and intramuscular injections.
Comparison Analysis of Two types of Electrical Circuits for Sensorless Brushless DC Motor Control (2015)

In this research, the effects of two types of electrical circuits, which detect back Electromotive Force (EMF) signals and output six step square waveform rotor position signals of 3 phase Brushless DC (BLDC) motors, on sensorless control are analyzed by implementing a coupled analysis of a Finite Elements Method (FEM) model of a BLDC motor and the electrical circuit. The 1st electrical circuit uses a dynamic threshold level which changes automatically according to the back EMF maximum level, and the 2nd electrical circuit uses a static threshold level which is determined at the start of motor control and is fixed regardless of the back EMF maximum level. Also, the results of the coupled analysis are verified by implementing experimental evaluation using an 8 pole 12 slot BLDC motor and embedded motor controller. Through this research, the advantages of the 1st electrical circuit is verified.
Linear combination steady-state free precession MRI (2000)

A new, fast, spectrally selective steady-state free precession (SSFP) imaging method is presented. Combining k-space data from SSFP sequences with certain phase schedules of radiofrequency excitation pulses permits manipulation of the spectral selectivity of the image. For example, lipid and water can be resolved. The contrast of each image depends on both T1 and T2, and the relative contribution of the two relaxation mechanisms to image contrast can be controlled by adjusting the flip angle. Several potential applications of the technique, referred to as linear combination steady-state free precession (LCSSFP), are demonstrated: fast musculoskeletal, abdominal, angiographic, and brain imaging.
Comprehensive mutation scanning of KCNQ1 in 111 Han Chinese patients with lone atrial fibrillation (2010)

Comprehensive mutation scanning of KCNQ1 did not identify novel pathogenic mutations or risk-conferring polymorphisms. As in Caucasians, genetic variation in KCNQ1 is not a common cause of AF in Han Chinese. Routine genetic testing of KCNQ1 for AF is, therefore, not warranted.
Reverse osmosis separation of polar organic compounds in aqueous solution (1976)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReverse osmosis separation of polar organic compounds in aqueous solutionHerbert H. P. Fang and Edward S. K. ChianCite this: Environ. Sci. Technol. 1976, 10, 4, 364–369Publication Date (Print):April 1, 1976Publication History Published online1 May 2002Published inissue 1 April 1976https://pubs.acs.org/doi/10.1021/es60115a011https://doi.org/10.1021/es60115a011research-articleACS PublicationsRequest reuse permissionsArticle Views399Altmetric-Citations36LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Non-destructive observation of damage in mortar and concrete during mechanical loading for the evaluation of moisture transfer profiles (2012)

Coupled heat and mass transfer modelling in building materials now plays an important part in the design of energy-efficient buildings. However, concrete and other construction materials subjected to mechanical loading and atmospheric excitation inevitably develop fractures patterns during their lifespan due to mechanical, chemical or physical damage processes. The target of the present work is to determine whether non-destructive observation of crack patterns can help predict the moisture uptake rate of fractured building materials. Digital image correlation was used to quantify damage in two types of materials. Moisture concentration profiles were then measured by X-ray radiography and calculated by finite element simulations in order to attempt to validate a moisture transfer model based on the fracture characterization. This procedure showed that the coupling of a mechanical characterization with a hygric modelling can provide an appropriate prediction of the water infiltration in fractured porous building materials.
Optimization of Transfer of Cold Atoms From TwoDimensional Magneto Optical Trap to ThreeDimensional Magneto Optical Trap (2018)

This thesis reports on the generation of MOT for laser cooling and trapping of Rubidium 87 atoms. Probe-pump technique have been used in Rb gas cell and doppler free absorption peaks has been observed. Peak at the crossover frequency will be locked for laser cooling and repump beams. This locked freuqency used in MOT to trap Rb atoms. The technique of optical molasses is used to cool the atoms and quadrupole magnetic field applied to confine or trap atoms at the center of MOT. Two chambers are constructed for 2D and 3D MOT with different pressure. Rb atoms loaded efficiently from the high flux cold atom beam generated in a compact 2D MOT. This is the first step of Bose Einstein Condensate (BEC). A performance of 2D MOT was tested by another main chamber of 3D MOT contains 3 pairs of counter-propagating beams. Over 5x10⁶ atoms trapped in a 3D MOT with loading rate of 1:8x10⁶ atoms/sec. This experiment provided an excellent starting point for future experiment on Rydberg atoms in dense ultracold quantum gases.
Current Knowledge on Viral Nervous Necrosis (VNN) and its Causative Betanodaviruses (2009)

Viral nervous necrosis (VNN) or viral encephalopathy and retinopathy (VER) caused by betanodaviruses (Nodaviridae) has seriously damaged global marine aquaculture since its first appearance in the late 1980s. In the past two decades, more than 100 papers have been published on the dis- ease. Although information is still limited, we now have more knowledge on the taxonomic position and molecular characteristics of betanodaviruses, and on the diagnosis, control, and infection mechanisms of the disease. This paper briefly reviews studies on VNN and betanodaviruses.
Fabrication and properties of PVA-TiO2 hydrogel composites (2012)

Abstract The preparation and properties of PVA-TiO2 hydrogel composites have been studied in this research. The results show that tensile strength and compression modulus of PVA-TiO2 hydrogel composites increased significantly, but the elongation did not changed obviously compared with the PVA hydrogel, indicating the good interaction between inorganic nanoparticles and organic polymer. Friction performance of the hydrogels was discussed, the friction of PVA-TiO2 hydrogel composites decrease than the PVA hydrogel and friction coefficient up to 0.001. The possible mechanism of friction was discussed.
Opponent Modeling in Negotiation Dialogues by Related Data Adaptation (2022)

Opponent modeling is the task of inferring another party's mental state within the context of social interactions. In a multi-issue negotiation, it involves inferring the relative importance that the opponent assigns to each issue under discussion, which is crucial for finding high-value deals. A practical model for this task needs to infer these priorities of the opponent on the fly based on partial dialogues as input, without needing additional annotations for training. In this work, we propose a ranker for identifying these priorities from negotiation dialogues. The model takes in a partial dialogue as input and predicts the priority order of the opponent. We further devise ways to adapt related data sources for this task to provide more explicit supervision for incorporating the opponent's preferences and offers, as a proxy to relying on granular utterance-level annotations. We show the utility of our proposed approach through extensive experiments based on two dialogue datasets. We find that the proposed data adaptations lead to strong performance in zero-shot and few-shot scenarios. Moreover, they allow the model to perform better than baselines while accessing fewer utterances from the opponent. We release our code to support future work in this direction: https://github.com/ kushalchawla/opponent-modeling.
Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia (2011)

Tumor-associated immune suppression can lead to defective T cell-mediated antitumor immunity. Here, we identified a unique phenotype of exhausted T cells in mice with advanced acute myelogenous leukemia (AML). This phenotype is characterized by the coexpression of Tim-3 and PD-1 on CD8(+) T cells in the liver, the major first site of AML metastases. PD-1 and Tim-3 coexpression increased during AML progression. PD-1(+)Tim-3(+) CD8(+) T cells were deficient in their ability to produce IFN-γ, TNF-α, and IL-2 in response to PD-1 ligand (PDL1) and Tim-3 ligand (galectin-9) expressing AML cells. PD-1 knockout (KO), which were partially resistant to AML challenge, up-regulated Tim-3 during AML progression and such Tim-3(+)PD-1- KO CD8(+) T cells had reduced cytokine production. Galectin-9 KO mice were more resistant to AML, which was associated with reduced T-regulatory cell accumulation and a modest induction of PD-1 and Tim-3 expression on CD8(+) T cells. Whereas blocking the PD-1/PDL1 or Tim-3/galectin-9 pathway alone was insufficient to rescue mice from AML lethality, an additive effect was seen in reducing-albeit not eliminating-both tumor burden and lethality when both pathways were blocked. Therefore, combined PD-1/PDL1 and Tim-3/galectin-9 blockade may be beneficial in preventing CD8(+) T-cell exhaustion in patients with hematologic malignancies such as advanced AML.
A data-management system using sensor technology and wireless devices for port security (2014)

Sensor technologies such as infrared sensors and hyperspectral imaging, video camera surveillance are proven to be viable in port security. Drawing from sources such as infrared sensor data, digital camera images and processed hyperspectral images, this article explores the implementation of a real-time data delivery system. In an effort to improve the manner in which anomaly detection data is delivered to interested parties in port security, this system explores how a client-server architecture can provide protected access to data, reports, and device status. Sensor data and hyperspectral image data will be kept in a monitored directory, where the system will link it to existing users in the database. Since this system will render processed hyperspectral images that are dynamically added to the server - which often occupy a large amount of space - the resolution of these images is trimmed down to around 1024&times;768 pixels. Changes that occur in any image or data modification that originates from any sensor will trigger a message to all users that have a relation with the aforementioned. These messages will be sent to the corresponding users through automatic email generation and through a push notification using Google Cloud Messaging for Android. Moreover, this paper presents the complete architecture for data reception from the sensors, processing, storage and discusses how users of this system such as port security personnel can use benefit from the use of this service to receive secure real-time notifications if their designated sensors have detected anomalies and/or have remote access to results from processed hyperspectral imagery relevant to their assigned posts.
Optimization of array element pitch for NDE applications (2015)

This paper quantitatively investigates how the pitch of elements in periodic ultrasonic arrays is related to the level of grating lobe artefacts in images. A theoretical framework is developed that enables the Point Spread Function of periodic arrays to be expressed as the sum of contributions from a main lobe and possible grating lobes. This analysis yields the classical array element pitch rules in the far-field, single-frequency case. However, numerical simulations show that the rules can be considerably relaxed in the near-field, broadband case without significantly compromising image quality. Results from artificially spatially-downsampled experimental data are presented to support this conclusion. Finally, extensions to other common inspection configurations are suggested.
Protein kinase C is not required for insulin stimulation of hexose uptake in muscle cells in culture (1987)

The L6 skeletal muscle cell line has been identified as a suitable model to study the action of insulin on glucose uptake in muscle [Klip, Li & Logan (1984) Am. J. Physiol. 247, E291-E296]. The signals that transfer information from occupied insulin receptors to glucose transporters remain unknown. Here we report that activation of protein kinase C by exogenous phorbol esters results in stimulation of glucose uptake. Protein C kinase activity was induced to migrate from the cytosolic fraction to the microsomal fraction after 40 min of exposure of intact cells to 4 beta-phorbol 12,13-dibutyrate. In contrast, incubation with insulin did not alter the subcellular distribution of the kinase. Prolonged preincubation of L6 cells with phorbol esters resulted in depletion of kinase C activity, whereas neither the basal rate of glucose uptake nor its stimulation by insulin were affected. This suggests that protein kinase C is expressed in L6 cells, and that insulin stimulation of hexose transport does not involve protein kinase C.
Rapid and specific detection of the thermostable direct haemolysin gene in Vibrio parahaemolyticus by the polymerase chain reaction (1993)

Synthetic oligonucleotide primers derived from a sequence of the thermostable direct haemolysin (tdh) gene were used in a polymerase chain reaction (PCR) amplification technique to detect this gene in strains of Vibrio parahaemolyticus. A total of 36 TDH-producing, and 89 TDH-negative Vibrio parahaemolyticus strains and 46 other vibrios and enteric pathogens were studied. In all, 36 strains of Vibrio parahaemolyticus from which the tdh gene could be successfully amplified by PCR were found to be TDH-positive in TDH haemolysin assay. No amplification products were obtained from Vibrio parahaemolyticus strains that were TDH-negative in the haemolysin assay or from other vibrios and enteric pathogens, with the exception of two strains. The PCR results were consistent with DNA hybridization tests. The detection limit for the tdh gene by PCR amplification was 40 pg of total DNA, or broth culture containing 1000 viable cells. Amplification products were confirmed by restriction enzyme digestion and Southern blot hybridization. The PCR method could detect the tdh sequences in stool samples from patients with gastroenteritis caused by V. parahaemolyticus. This PCR protocol clearly identified TDH-producing strains of V. parahaemolyticus and provides an alternative to conventional methods for TDH detection by research laboratories, clinical laboratories, regulatory agencies, and the seafood industry.
Increasing the midsole bending stiffness of shoes alters gastrocnemius medialis muscle function during running (2021)

In recent years, increasing the midsole bending stiffness (MBS) of running shoes by embedding carbon fibre plates in the midsole resulted in many world records set during long-distance running competitions. Although several theories were introduced to unravel the mechanisms behind these performance benefits, no definitive explanation was provided so far. This study aimed to investigate how the function of the gastrocnemius medialis (GM) muscle and Achilles tendon is altered when running in shoes with increased MBS. Here, we provide the first direct evidence that the amount and velocity of GM muscle fascicle shortening is reduced when running with increased MBS. Compared to control, running in the stiffest condition at 90% of speed at lactate threshold resulted in less muscle fascicle shortening (p = 0.006, d = 0.87), slower average shortening velocity (p = 0.002, d = 0.93) and greater estimated Achilles tendon energy return (p ≤ 0.001, d = 0.96), without a significant change in GM fascicle work (p = 0.335, d = 0.40) or GM energy cost (p = 0.569, d = 0.30). The findings of this study suggest that running in stiff shoes allows the ankle plantarflexor muscle-tendon unit to continue to operate on a more favourable position of the muscle's force-length-velocity relationship by lowering muscle shortening velocity and increasing tendon energy return.
Mechanical characterisation and modelling of electrospun materials for biomedical applications (2015)

Electrospun nonwovens, due to their intrinsic beneficial properties, have found many applications in biomedical areas such as tissue engineering, drug delivery, or active wound management. Exploiting its porous structure, electrospun is often used as scaffolds for tissue growth which can be stimulated by mechanical properties of the structure. Cells proliferation can be controlled by stress distribution in the scaffold, thus improving its efficiency. Anticipation of this parameter is possible by using Finite Elements Model of electrospun structure presented in this study. Fully parametric model of nonwoven material with random fibrous distribution was developed enabling the calculation of mechanical properties of material on the basis of input parameters such as mechanical characteristics and geometry of single component fibres. Relatively low production ratio of electrospinning process and time consuming characterisation methods were motivation to develop the tool that would shorten the design and optimisation of electrospun materials. The model was validated experimentally by mechanical testing of electrospun material; modelling and experimental results were in a good agreement.
Correction to: Advances in the automated synthesis of 6-[18F]Fluoro-L-DOPA (2021)

An amendment to this paper has been published and can be accessed via the original article.
On the study of workpiece localization with a cost-effective vision based method (2015)

In a factory automation application, position measurement of a workpiece is crucial. Computer vision is one of the most important methods for localizing the workpiece. Special equipment, such as a camera and a laser range finder are often used to measure and detect the position of the workpiece. However, the process of obtaining these measurements are usually highly specialized and expensive. Our method concentrates on improving the accuracy of the workpiece position measurement without expensive equipment. We use Kinect as the 3D sensor, which consists of a RGB camera and a depth camera. First mark points in both the Kinect coordinate and the manipulator coordinate are obtained. Then calibration between Kinect and Manipulator is obtained using Quasi-Newton method with the initial mark points. In order to improve the accuracy, we propose an improved registration based on Iterative Closest Point (ICP) to further derive the final transformation matrix. Experiment shows that this comprehensive method is practical.
Generative adversarial network based adaptive data augmentation for handwritten Arabic text recognition (2022)

Training deep learning based handwritten text recognition systems needs a lot of data in terms of text images and their corresponding annotations. One way to deal with this issue is to use data augmentation techniques to increase the amount of training data. Generative Adversarial Networks (GANs) based data augmentation techniques are popular in literature especially in tasks related to images. However, specific challenges need to be addressed in order to effectively use GANs for data augmentation in the domain of text recognition. Text data is inherently imbalanced in terms of frequency of different characters appearing in training samples and the training data as a whole. GANs trained on the imbalanced dataset leads to augmented data that does not represent the minority characters well. In this paper, we present an adaptive data augmentation technique using GANs that deals with the issue of class imbalance arising in text recognition problems. We show, using experimental evaluations on two publicly available datasets for handwritten Arabic text recognition, that the GANs trained using the presented technique is effective in dealing with class imbalanced problem by generating augmented data that is balanced in terms of character frequencies. The resulting text recognition systems trained on the balanced augmented data improves the text recognition accuracy as compared to the systems trained using standard techniques.
Minimally invasive techniques in colon surgery. (2008)

With the description of the first laparoscopic cholecystectomy in 1985, minimally invasive approaches have become the standard practice of surgeons in managing several disease processes. This has been mainly driven by the significant favorable impact of minimally invasive surgery on patient related outcomes. Smaller incisions lead to improved cosmesis, reduced postoperative pain and earlier return of gastrointestinal function. These factors in turn contribute to a faster recovery of the patient (compared to similar open procedures) with a reduced utilization of hospital resources, reduced costs and earlier return of the patient to normal routines of daily life and work. With experience it is clear that these favorable patient outcomes can also be seen with minimally invasive surgery for various colonic diseases and procedures. Many of the early concerns regarding minimally invasive approaches such as port site recurrence and the feasibility of adequate oncologic resections have been laid to rest by multiple randomized trials. There are now documented benefits to minimally invasive approaches for colonic diseases such as cancer, inflammatory bowel disease and diverticular disease; as long as surgeons choose the appropriate patients and spend the time and resources needed to become proficient at these advanced procedures.