gebhart/patrepeval huggingface dataset:
Detecting and tracking body parts of multiple people (2002)

Tracking of people and their body parts has found application in image processing and computer vision. This paper describes a framework for tracking body parts (eg, hands and face) of multiple people in image sequences. We use a probabilistic model to fuse color and motion information to localize the body parts and employ the multiple hypothesis tracking (MHT) algorithm to track these features simultaneously. We incorporate a path coherence function along with MHT to reduce the negative effects of spurious measurements that produce unconvincing tracks and needless computations. The performance of the framework is validated using experiments on synthetic and real sequences of images.
An incident detection system based on semantic hierarchy (2005)

Japan and EU governments aim to reduce the mortal rate from traffic accidents by 50% at the end of 2010. To achieve this goal, sufficient information about accidents need to be gathered, so investigators can evaluate for causes and how to prevent the future accidents. In this paper, we develop three algorithms for automatic event detection, and provide video clip during accidents as our results. Three algorithms are (1) logical reasoning focusing on an individual behavior, (2) logical reasoning focusing on relative behavior and (3) classification with continuous variables by hyper-plane. Our algorithms utilize a semantic hierarchy composed of three kinds of operators (coordinate-class, behavior-class, event-class). The three operating classes provide the context of traffic events similar to the understanding of a human operator on traffic scenes. We evaluate algorithms on actual traffic scene taken for 18 months. Our algorithms can detect more than 90%.
Zertifizierungsmöglichkeiten nach ISO/IEC 27000 (2022)

No AccessPraxisbuch ISO/IEC 27001Oct 2022Zertifizierungsmöglichkeiten nach ISO/IEC 27000Michael Brenner, Nils gentschen Felde, Wolfgang Hommel, Stefan Metzger, Helmut Reiser, Thomas SchaafMichael Brenner, Nils gentschen Felde, Wolfgang Hommel, Stefan Metzger, Helmut Reiser, Thomas Schaafhttps://doi.org/10.3139/9783446474581.007SectionsAboutPDF ToolsAdd to FavoritesDownload CitationTrack CitationsCopy LTI LinkPDF key 'share (en)' returned an object instead of string.FacebookTwitterEmailLinkedIn previous chapternext chapter FiguresReferencesRelatedDetails 2022Pages: 157-168Print ISBN: 978-3-446-47395-9eISBN: 978-3-446-47458-1 Copyright & Permissions© 2022 Carl Hanser Verlag GmbH & Co. KGPDF downloadLoading ...
The role of a potential c-Myc/Max binding site on the bovine leukemia virus long terminal repeat transcriptional activity (1996)

info:eu-repo/semantics/published
An Approximation of Continuity of Lenticular Mesaverde Sandstone Lenses Utilizing Close-Well Correlations, Piceance Basin, Northwestern Colorado (1983)

ABSTRACT Mesaverde Group sandstone units in 13 closely-spaced wells in the central and southern Piceance Basin of Colorado were correlated utilizing wireline log response quantitatively and qualitatively. Based on these correlations, the environmental subdivisions of the Mesaverde Group were characterized as follows:Paralic (upper mixed-marine) zone, occuring in the uppermost Mesaverde Group, includes thick sandstone units which are interpreted to be regionally continuous.Fluvial zone, containing point-bars 20 to 30+ ft thick, is interpreted to be correlatable to a maximum of 6,300 ft.Paludal zone has insufficient data to adequately characterize the sand units. However, 63 percent of the units are correlatable across at least 139 ft. An approximation of the dimensional characteristics of Mesaverde sandstone units has potential applications in designing hydraulic fracturing treatments and estimating gas reserves more accurately.
A test on the candle-power of an enclosed arc lamp (1897)

Thesis (B.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering, 1897.
Silencing of the human microsomal glucose‐6‐phosphate translocase induces glioma cell death: Potential new anticancer target for curcumin (2006)

G6P translocase (G6PT) is thought to play a crucial role in transducing intracellular signaling events in brain tumor-derived cancer cells. In this report, we investigated the contribution of G6PT to the control of U-87 brain tumor-derived glioma cell survival using small interfering RNA (siRNA)-mediated suppression of G6PT. Three siRNA constructs were generated and found to suppress up to 91% G6PT gene expression. Flow cytometry analysis of propidium iodide/annexin-V-stained cells indicated that silencing the G6PT gene induced necrosis and late apoptosis. The anticancer agent curcumin, also inhibited G6PT gene expression by more than 90% and triggered U-87 glioma cells death. Overexpression of recombinant G6PT rescued the cells from curcumin-induced cell death. Targeting G6PT expression may provide a new mechanistic rationale for the action of chemopreventive drugs and lead to the development of new anti-cancer strategies.
Co-transcriptional formation of DNA:RNA hybrid G-quadruplex and potential function as constitutional cis element for transcription control (2013)

G-quadruplex formation in genomic DNA is considered to regulate transcription. Previous investigations almost exclusively focused on intramolecular G-quadruplexes formed by DNA carrying four or more G-tracts, and structure formation has rarely been studied in physiologically relevant processes. Here, we report an almost entirely neglected, but actually much more prevalent form of G-quadruplexes, DNA:RNA hybrid G-quadruplexes (HQ) that forms in transcription. HQ formation requires as few as two G-tracts instead of four on a non-template DNA strand. Potential HQ sequences (PHQS) are present in >97% of human genes, with an average of 73 PHQSs per gene. HQ modulates transcription under both in vitro and in vivo conditions. Transcriptomal analysis of human tissues implies that maximal gene expression may be limited by the number of PHQS in genes. These features suggest that HQs may play fundamental roles in transcription regulation and other transcription-mediated processes.
Le projet de réforme du droit des obligations : incidences sur le régime des cessions de droits sociaux (2015)

à venir
Video search (2010)

This panel will debate various approaches to improving video search, and explore how professional cataloguing, crowd sourced metadata, and improvements in search algorithms will evolve over the next ten years. Panelists will explore the needs of large scale video archives, and compare these against the current capabilities of video search.
Molecular Dynamics Simulations Reveal Proton Transfer Pathways in Cytochrome C-Dependent Nitric Oxide Reductase (2012)

Nitric oxide reductases (NORs) are membrane proteins that catalyze the reduction of nitric oxide (NO) to nitrous oxide (N(2)O), which is a critical step of the nitrate respiration process in denitrifying bacteria. Using the recently determined first crystal structure of the cytochrome c-dependent NOR (cNOR) [Hino T, Matsumoto Y, Nagano S, Sugimoto H, Fukumori Y, et al. (2010) Structural basis of biological N2O generation by bacterial nitric oxide reductase. Science 330: 1666-70.], we performed extensive all-atom molecular dynamics (MD) simulations of cNOR within an explicit membrane/solvent environment to fully characterize water distribution and dynamics as well as hydrogen-bonded networks inside the protein, yielding the atomic details of functionally important proton channels. Simulations reveal two possible proton transfer pathways leading from the periplasm to the active site, while no pathways from the cytoplasmic side were found, consistently with the experimental observations that cNOR is not a proton pump. One of the pathways, which was newly identified in the MD simulation, is blocked in the crystal structure and requires small structural rearrangements to allow for water channel formation. That pathway is equivalent to the functional periplasmic cavity postulated in cbb(3) oxidase, which illustrates that the two enzymes share some elements of the proton transfer mechanisms and confirms a close evolutionary relation between NORs and C-type oxidases. Several mechanisms of the critical proton transfer steps near the catalytic center are proposed.
Peptides and Peptidomimetics as Potential Antiobesity Agents: Overview of Current Status (2019)

There is a high occurrence of obesity worldwide without many new medications being approved for its treatment. Therefore, there is an urgent need to introduce new approaches for treating obesity. Bioactive peptides have been used to treat metabolic disorders- such as type-2 diabetes and obesity; while also possessing anti-oxidant, anti-inflammatory, anti-microbial, and anti-viral properties. However, the development of these peptides has taken backstage due to their size, reduced stability, poor delivery and bioavailability, fast rate of degradation etc. But with the emergence of newer techniques for multifunctional peptides, mimetics, peptide analogs, and aptamers, there is a sudden revival in this therapeutic field. An increased attention is required for development of the natural peptides from food and marine sources which can mimic the function of mediators involved in weight management to avoid obesity. Herein, the search for the structures of anti-obesity peptides was carried out in order to establish their potential for drug development in future. An extensive search for the current status of endogenous, food and marine peptides, with reference to novel and interesting experimental approaches based on peptidomimetics for controlling obesity, was performed. Apolipoprotein A-I (apoA-I), melanocortin-4 receptor (MC4R)-specific agonist, GLP-1 dual and triple agonists, neuropeptides and prolactin-releasing peptide mimetics were specifically examined for their anti-obesity role. Novel peptides, mimetics, and synthesis interventions are transpiring and might offer safer alternatives for otherwise scarcely available safe antiobesity drug. A deeper understanding of peptides and their chemistry through the use of peptide engineering can be useful to overcome the disadvantages and select best mimetics and analogs for treatment in future.
Tailoring the Surface of Perovskite through In Situ Growth of Ru/RuO2 Nanoparticles as Robust Symmetrical Electrodes for Reversible Solid Oxide Cells (2020)

Abstract Although numerous perovskite oxides can enhance the electrochemical activity via exsolved metallic nanoparticles on the surface, most of them can only be applied as catalysts in a reducing atmosphere. These nanoparticles cause serious performance degradation in oxidizing conditions due to the formation of low‐conductive metal oxides. This poses a big challenge to the design of highly active catalysts of electrochemical devices, especially for symmetrical solid oxide cells. Herein, based on the strategy of exsolved metallic nanoparticles in A‐site deficient perovskite, a unique and simple method is demonstrated for the synthesis of Ru/RuO 2 nanoparticles on the surface of perovskite oxide via in situ growth. The electrode material (La 0.75 Sr 0.25 ) 0.9 Cr 0.5 Mn 0.45 Ru 0.05 O 3− δ (LSCMR) is designed through careful choice of composition and the core idea is to make use of the exsolved nanoparticles concept applied for the first time at both hydrogen electrode and oxygen electrode for symmetrical solid oxide cells. Inspired by exsolved Ru and RuO 2 , the surface‐decorated LSCMR exhibits significantly enhanced electrochemical activity for both H 2 and O 2 , respectively, accompanied by high redox long‐term stability. Moreover, simple, low‐cost, and environmental‐friendly synthesis of Ru/RuO 2 nanoparticles on the substrate of typical perovskites is realized with this in situ growth approach.
National Trends in Parathyroid Surgery from 1998 to 2008: A Decade of Change (2009)

This survey formally documents the evolution of practice patterns in parathyroid surgery over the last decade. Although LE has achieved wide acceptance, surgical management of hyperparathyroidism has become increasingly disparate. This trend may highlight a need to define best-practice guidelines.
Integrated planar lightwave bio/chem OEIC sensors on Si CMOS circuits (2005)

Optical sensing, and the integration of sensors and electronics into Sensor on a Chip and Sensor on a Package systems are an approach to the creation of miniaturized, portable, customizable, low cost sensor systems for rapid health diagnostics, medical research, environmental monitoring, and security monitoring. To integrate optical sensing systems that are autonomous, it is essential to integrate the sensor, light source, and light detection into a single substrate or chip. The integration of this optical system with signal control and processing electronics enable discrimination with individually customized sensors in sensor arrays, and high sensitivity levels. Thin film optoelectronic active device integration with planar optical passive devices is a heterogeneous integration method for fabricating planar lightwave integrated circuits at the chip level and planar lightwave integrated systems at the substrate and package level.
Associations Between Posttransplantation Diabetes Mellitus and Renal Graft Survival (2016)

The present study confirms previous findings of an increased risk of overall but not death-censored renal graft loss in renal transplant recipients with PTDM. Longstanding diabetes might increase the risk of acute rejections.
A CD40/CD40L feedback loop drives the breakdown of CD8+T‐cell tolerance following depletion of suppressive CD4+ T cells (2014)

Dendritic cells (DCs) are the key APCs not only for the priming of naïve T cells, but also for the induction and maintenance of peripheral T-cell tolerance. We have recently shown that cognate interactions between Foxp3(+) Tregs and steady-state DCs are crucial to maintain the tolerogenic potential of DCs. Using DIETER mice, which allow the induction of antigen presentation selectively on DCs without altering their maturation status, we show here that breakdown of CD8(+) T-cell tolerance, which ensues after depletion of suppressive CD4(+) T cells, is driven by a positive feedback loop in which autoreactive CD8(+) T cells activate DCs via CD40. These data identify ligation of CD40 on DCs as a stimulus that promotes autoreactive T-cell priming when regulatory T-cell suppression fails and suggest that feedback from autoreactive T cells to DCs may contribute to the well-documented involvement of CD40 in many autoimmune diseases.
Biomass Conversion to Mixed Alcohol Fuels Using the MixAlco Process (1997)

The MixAlco Process converts biomass into mixed alcohol fuels. The biomass is first treated with lime to render it more digestible. Then, it is fed to a mixed culture of acid-forming microorganisms that produce salts of volatile fatty acids, such as calcium acetate, propionate, and butyrate. These salts are separated from the fermentation broth and thermally converted to ketones that are subsequently hydrogenated to alcohols, such as 2-propanol, 2-butanol, 2-pentanol, and 3-pentanol. Design data are presented related to the lime treatment, fermentation, thermal conversion, and hydrogenation. A preliminary economic evaluation indicates that alcohol fuels can be produced from negative-value biomass, such as municipal solid waste and sewage sludge, for about $0.19/L ($0.72/gal).
14th World Congress on Advances in Stem Cell Research and Regenerative Medicine. (2019)

International audience
A bitmap coding method for P2P streaming protocols (2010)

To reduce signal overhead, we present a bitmap coding method which just codes changing bits between two continuous bitmaps sent by the same peer. Our method has a novel characteristic that the smaller the bitmap exchange interval is, the shorter the coded sequence is. The average compression ratio of our method is 13.46:1 for real bitmaps crawled from PPLive. For the same bitmap crawled from UUSee, the average compression ratio of UUSee's coding method is 6.26:1, but that of our method is 9.96:1. Besides high compression ratio, our method is also very simple for coding and decoding.
Predictive Nephrotoxicity Profiling of a Novel Antifungal Small Molecule in Comparison to Amphotericin B and Voriconazole (2020)

SM21 had a significantly better safety profile in terms of nephrotoxicity with no major tubular epithelial abnormalities observed in kidney cells and no augmentation of kidney injury biomarkers compared to AmB. Kim-1 and CLU were the most sensitive biomarkers for detection of AmB-induced kidney damage. Future clinical trials should consider inclusion of these novel biomarkers as early indicators of acute kidney injury in antifungal-induced nephrotoxicity.
A high resolution atlas of gene expression in the domestic sheep ( Ovis aries ) (2017)

Abstract Sheep are a key source of meat, milk and fibre for the global livestock sector, and an important biomedical model. Global analysis of gene expression across multiple tissues has aided genome annotation and supported functional annotation of mammalian genes. We present a large-scale RNA-Seq dataset representing all the major organ systems from adult sheep and from several juvenile, neonatal and prenatal developmental time points. The Ovis aries reference genome (Oar v3.1) includes 27,504 genes (20,921 protein coding), of which 25,350 (19,921 protein coding) had detectable expression in at least one tissue in the sheep gene expression atlas dataset. Network-based cluster analysis of this dataset grouped genes according to their expression pattern. The principle of ‘guilt by association’ was used to infer the function of uncharacterised genes from their co-expression with genes of known function. We describe the overall transcriptional signatures present in the sheep gene expression atlas and assign those signatures, where possible, to specific cell populations or pathways. The findings are related to innate immunity by focusing on clusters with an immune signature, and to the advantages of cross-breeding by examining the patterns of genes exhibiting the greatest expression differences between purebred and crossbred animals. This high-resolution gene expression atlas for sheep is, to our knowledge, the largest transcriptomic dataset from any livestock species to date. It provides a resource to improve the annotation of the current reference genome for sheep, presenting a model transcriptome for ruminants and insight into gene, cell and tissue function at multiple developmental stages. Author Summary Sheep are ruminant mammals kept as livestock for the production of meat, milk and wool in agricultural industries across the globe. Genetic and genomic information can be used to improve production traits such as disease resiliance. The sheep genome is however missing important information relating to gene function and many genes, which may be important for productivity, have no informative gene name. This can be remedied using RNA-Sequencing to generate a global expression profile of all protein-coding genes, across multiple organ systems and developmental stages. Clustering genes based on their expression profile across tissues and cells allows us to assign function to those genes. If for example a gene with no informative gene name is expressed in macrophages and is found within a cluster of known macrophage related genes it is likely to be involved in macrophage function and play a role in innate immunity. This information improves the quality of the reference genome and provides insight into biological processes underlying the complex traits that influence the productivity of sheep and other livestock species.
Fused Morphlinopyrimidines and Methods of Use Thereof (2015)

ADVERTISEMENT RETURN TO ISSUEPREVPatent HighlightNEXTFused Morphlinopyrimidines and Methods of Use ThereofBenjamin Blass*View Author Information Temple University School of Pharmacy, 3307 North Broad Street, Philadelphia, Pennsylvania 19140, United States*Tel: 215-707-1085. E-mail: [email protected]Cite this: ACS Med. Chem. Lett. 2015, 6, 8, 836–837Publication Date (Web):July 13, 2015Publication History Received28 June 2015Published online13 July 2015Published inissue 13 August 2015https://pubs.acs.org/doi/10.1021/acsmedchemlett.5b00259https://doi.org/10.1021/acsmedchemlett.5b00259editorialACS PublicationsCopyright © 2015 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views663Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (358 KB) Get e-AlertscloseSUBJECTS:Alkyls,Biopolymers,Heterocyclic compounds,Nervous system diseases,Peptides and proteins Get e-Alerts
Risk of relapse of multiple myeloma following kidney transplantation (2018)

Forty percent of our cohort experienced a relapse in MM within 2 years of kidney transplantation. Death-censored graft survival and patient survival were 80% at 4 years. Our study adds to the growing literature supporting kidney transplantation following successful ASCT for MM and is useful when counselling patients regarding renal and haematological outcomes.
Linear Systems, Sparse Solutions, and Sudoku (2009)

In this paper, we show that Sudoku puzzles can be formulated and solved as a sparse linear system of equations. We begin by showing that the Sudoku ruleset can be expressed as an underdetermined linear system: Ax = b, where A is of size m times n and n > m. We then prove that the Sudoku solution is the sparsest solution of Ax = b, which can be obtained by lo norm minimization, i.e. min ||x:|| <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> s.t. Ax = b. Instead of this minimization SB problem, inspired by the sparse representation literature, we solve the much simpler linear programming problem of minimizing the l <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sub> norm of x, i.e. min ||x|| <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sub> s.t. Ax = b, and show numerically that this approach solves representative Sudoku puzzles.