gebhart/patrepeval huggingface dataset:
MouldingNet: Deep-learning for 3D Object Reconstruction (2019)

The rise of deep neural networks a number of approaches for learning over 3D data have gained popularity. In this paper, we take advantage of one of these approaches, bilateral convolutional layers to propose a novel end-to-end deep auto-encoder architecture to efficiently encode and reconstruct 3D point clouds. Bilateral convolutional layers project the input point cloud onto an even tessellation of a hyperplane in the (d Å1)-dimensional space known as the permutohedral lattice and perform convolutions over this representation. In contrast to existing point cloud based learning approaches, this allows us to learn over the underlying geometry of the object to create a robust global descriptor. We demonstrate its accuracy by evaluating across the shapenet and modelnet datasets, in order to illustrate 2 main scenarios, known and unknown object reconstruction. These experiments show that our network generalises well from seen classes to unseen classes.
Chlorophyll Catabolites in Senescent Leaves of the Lime Tree (Tilia cordata) (2012)

In cold extracts of senescent leaves of the Lime tree (Tilia cordata), two colorless nonfluorescent chlorophyll catabolites (NCCs) were identified, named Tc-NCC-1 and Tc-NCC-2, as well as a polar yellow chlorophyll catabolite (YCC), named Tc-YCC. The constitution of the two NCCs was determined by spectroscopic means. In addition, a tentative structure was derived for Tc-YCC. The three chlorophyll degradation products exhibited tetrapyrrolic structures, as are typical of NCCs or YCCs, and turned out to be rather polar, due to a glucopyranosyl group at their 8(2)-position. At their 3-positions, the more polar Tc-NCC-1 carried a 1,2-dihydroxyethyl group and the less polar Tc-NCC-2 a vinyl group. Tc-YCC was identified as the product of an oxidation of Tc-NCC-1.
Improper Gaussian signaling for the Z-interference channel (2014)

The optimal transmission scheme for a multiple-input multiple-output point-to-point channel (MIMO-P2P) is dependent on the type of received interference, which can be either proper or improper. We will show that the presence of improper interference is beneficial in terms of improving the achievable rate compared to a case with proper interference. These benefits are due to using widely linear precoder and receiver. Additionally, we investigate a cellular scenario where two types of users are coexisting, ones that are receiving proper interference while others which might be receiving improper interference, trying to devise the best transmission scheme to be adopted. We propose an improper Gaussian signaling-based scheme that allows controlling system performance and fairness in terms of bitrate through a single parameter.
Intranasal anti‐caspase‐1 therapy preserves myelin and glucose metabolism in a model of progressive multiple sclerosis (2020)

Inflammatory demyelination and axonal injury in the central nervous system (CNS) are cardinal features of progressive multiple sclerosis (MS), and linked to activated brain macrophage-like cells (BMCs) including resident microglia and trafficking macrophages. Caspase-1 is a pivotal mediator of inflammation and cell death in the CNS. We investigated the effects of caspase-1 activation and its regulation in models of MS. Brains from progressive MS and non-MS patients, as well as cultured human oligodendrocytes were examined by transcriptomic and morphological methods. Next generation transcriptional sequencing of progressive MS compared to non-MS patients' normal appearing white matter (NAWM) showed induction of caspase-1 as well as other inflammasome-associated genes with concurrent suppression of neuron-specific genes. Oligodendrocytes exposed to TNFα exhibited upregulation of caspase-1 with myelin gene suppression in a cell differentiation state-dependent manner. Brains from cuprizone-exposed mice treated by intranasal delivery of the caspase-1 inhibitor, VX-765 or its vehicle, were investigated in morphological and molecular studies, as well as by fluorodeoxyglucose-positron emission tomography (FDG-PET) imaging. Cuprizone exposure resulted in BMC and caspase-1 activation accompanied by demyelination and axonal injury, which was abrogated by intranasal VX-765 treatment. FDG-PET imaging revealed suppressed glucose metabolism in the thalamus, hippocampus and cortex of cuprizone-exposed mice that was restored with VX-765 treatment. These studies highlight the caspase-1 dependent interactions between inflammation, demyelination, and glucose metabolism in progressive MS and associated models. Intranasal delivery of an anti-caspase-1 therapy represents a promising therapeutic approach for progressive MS and other neuro-inflammatory diseases.
The Impact of Behavioral Intervention on Obesity Mediated Declines in Mobility Function: Implications for Longevity (2011)

A primary focus of longevity research is to identify prognostic risk factors that can be mediated by early treatment efforts. To date, much of this work has focused on understanding the biological processes that may contribute to aging process and age-related disease conditions. Although such processes are undoubtedly important, no current biological intervention aimed at increasing health and lifespan exists. Interestingly, a close relationship between mobility performance and the aging process has been documented in older adults. For example, recent studies have identified functional status, as assessed by walking speed, as a strong predictor of major health outcomes, including mortality, in older adults. This paper aims to describe the relationship between the comorbidities related to decreased health and lifespan and mobility function in obese, older adults. Concurrently, lifestyle interventions, including diet and exercise, are described as a means to improve mobility function and thereby limit the functional limitations associated with increased mortality.
Role of the gut proteinases from mosquito larvae in the mechanism of action and the specificity of the Bacillus sphaericus toxin (1990)

Gut proteinases from larvae of mosquito species both susceptible and not susceptible to Bacillus sphaericus converted the 43-kDa toxin to a 40-kDa polypeptide exhibiting enhanced cytotoxicity to mosquito cell cultures. The toxin was also activated by gut proteinases from the nonsusceptible Lepidoptera Spodoptera littoralis in vitro and in vivo. Therefore, the specificity of Bacillus sphaericus toxin does not seem to be determined by gut proteinase action. However, susceptibility of mosquito cell cultures did not reflect the specificity of the toxin, which must now be investigated at the cellular level in the larvae.
Subtle genetic changes enhance virulence of methicillin resistant and sensitive Staphylococcus aureus (2007)

USA300-MRSA is highly similar to other MRSA strains based on whole genome alignments and gene content, indicating that the differences in pathogenesis are due to subtle changes rather than to large-scale acquisition of virulence factor genes. The USA300 Houston isolate differs from another sequenced USA300 strain isolate, derived from a patient in San Francisco, in plasmid content and a number of sequence polymorphisms. Such differences will provide new insights into the evolution of pathogens.
Processed data for "Distinguishing features of High Altitude Negative Leaders as observed with LOFAR" (2021)

This is data for "Distinguishing feartures of High Altitude Negative Leaders as observed with LOFAR". Each file is in text. The first two lines are mostly unused, except for the first 8 numbers of the first line which give the bounding box of the data in this format: (min_east max_east min_north max_north min_altitude max_altitude min_time max_time). Where east, north, and altitude are in units of km from LOFAR's core. and time is in units of ms from start of the flash. The following rows (after the first two) give the data. The first five columns are: label ; time [ms] ; east [km] ; north [km] ; height [km] ; pulse power [arb. units] any following columns (if present) are pulse-shape data that are not used at present.
Photoageing of cardanol: characterization, circumvention by side chain methoxylation and application for photocrosslinkable polymers (2015)

Photoageing of cardanol and its limitation by methoxylation of the side chain to produce photocrosslinkable copolymers of tunable reactivity.
Cannabis. XIII. Two new spiro-compounds, cannabispirol and acetyl cannabispirol. (1978)

Two new spiro-compounds, cannabispirol and acetyl cannabispirol, were isolated along with cannabispirone and cannabispirenone from the Japanese domestic cannabis and these structures were elucidated. The biogenetic relationship of spiro-compounds and cannabinoids was also discussed.
Computational Intelligence: A Development Environment for Telecommunications Networks (2018)

In this chapter, we introduce a concept of Computational Intelligence (CI), define its key components—contributing technologies of neurocomputing, granular computing, especially fuzzy sets, and evolutionary methods, and discuss the underlying design methodology. Subsequently, we elaborate on the use of CI as the design and analysis venue of telecommunications systems, especially ATM networks and active networks.
Mental Health of Refugees and Torture Survivors: A Critical Review of Prevalence, Predictors, and Integrated Care (2019)

Civilian war trauma and torture rank among the most traumatic life experiences; exposure to such experiences is pervasive in nations experiencing both internal and external conflict. This has led to a high volume of refugees resettling throughout the world with mental health needs that primary care physicians may not be screening for and prepared to effectively address. In this article, we review the literature on demographics, predictors, mental health outcomes of torture, and integrated care for the mental health needs of refugees. We searched PubMed and PSYCINFO databases for original research articles on refugees and mental health published in the English language between 2010 and present. Nine percent of 720 adults in conflict areas in Nepal, with predominance of literate married males, met the threshold for Post-Traumatic Stress Disorder (PTSD), 27.5% for depression, and 22.9% for anxiety. While, PTSD rate has been documented as high as 88.3% among torture survivors from Middle East (ME), Central Africa (CA), South Asia (SA), Southeast Europe (SE). Depression was recorded as high as 94.7% among 131 African torture survivors and anxiety as high as 91% among 55 South African torture survivors. Torture severity, post-migration difficulties, and wait time to receive clinical services were significantly associated with higher rate of mental health symptoms. Mental health screening is not a standard component of initial physical exams for refugees, yet these individuals have had high trauma exposure that should inform clinical care. Integrated care models are lacking but would greatly benefit this community to prevent progression to greater severity of mental health symptoms.
Authorship Attribution (2008)

Authorship attribution, the science of inferring characteristics of the author from the characteristics of documents written by that author, is a problem with a long history and a wide range of application. Recent work in “non-traditional” authorship attribution demonstrates the practicality of automatically analyzing documents based on authorial style, but the state of the art is confusing. Analyses are difficult to apply, little is known about type or rate of errors, and few “best practices” are available. In part because of this confusion, the field has perhaps had less uptake and general acceptance than is its due. This review surveys the history and present state of the discipline, presenting some comparative results when available. It shows, first, that the discipline is quite successful, even in difficult cases involving small documents in unfamiliar and less studied languages; it further analyzes the types of analysis and features used and tries to determine characteristics of well-performing systems, finally formulating these in a set of recommendations for best practices.
Tularemia (1985)

EVANS, MARTIN E. M.D.; GREGORY, DAVID W. M.D.; SCHAFFNER, WILLIAM M.D.; MCGEE, ZELL A. M.D. Author Information
Is the anti-inflammatory effect of regular exercise responsible for reduced cardiovascular disease? (2007)

Engaging in regular physical activity reduces the risk of developing CVD (cardiovascular disease), but it is not certain to what degree this may be due to the anti-inflammatory effects of exercise. Following acute exercise, there is a transient increase in circulating levels of anti-inflammatory cytokines, whereas chronic exercise reduces basal levels of pro-inflammatory cytokines. Exercise training also induces the expression of antioxidant and anti-inflammatory mediators in the vascular wall that may directly inhibit the development of atherosclerosis. Limited studies in humans and more comprehensive assessments in animal models have confirmed that exercise is atheroprotective and helped identify a number of the mechanisms to explain these effects. This review explores the relationship between systemic and vascular wall inflammation and the role that the anti-inflammatory effects of exercise have on the development and progression of CVD.
Efficient Optical Modulator by Reverse-biased III-V/Si Hybrid MOS Capacitor based on FK Effect and Carrier Depletion (2019)

We present efficient optical phase modulation based on Franz-keldysh effect and carrier depletion in reverse-biased III-V/Si hybrid MOS capacitor. The high modulation efficiency and small capacitance enables significant improvement in modulation bandwidth and modulation energy.
New-generation TAVI devices: description and specifications (2014)

Transcatheter aortic valve implantation (TAVI) is an established treatment for inoperable patients or patients at high risk for surgery. Despite growing experience, issues remain associated with first-generation TAVI devices, including valve malpositioning, vascular complications, paravalvular regurgitation and conduction disorders. Several second-generation TAVI devices, aimed at addressing these issues, are CE marked or under evaluation for CE marking. The objective of this overview is to describe and illustrate the key design features of the second-generation devices that are entering contemporary clinical practice.
Direct α-Oxytosylation of Ketones by Using Pentavalent Organobismuth Reagents (2008)

Abstract A new method for the preparation of α-tosyloxy ketones by a direct oxytosylation of ketones using a combination of heterocyclic pentavalent organobismuth compounds and p-toluenesulfonic acid monohydrate is described.
From reporters to endogenous genes: the impact of the first five codons on translation efficiency in Escherichia coli (2019)

ABSTRACT Translation initiation is a critical step in the regulation of protein synthesis, and it is subjected to different control mechanisms, such as 5’ UTR secondary structure and initiation codon context, that can influence the rates at which initiation and consequentially translation occur. For some genes, translation elongation also affects the rate of protein synthesis. With a GFP library containing nearly all possible combinations of nucleotides from the 3 rd to the 5 th codon positions in the protein coding region of the mRNA, it was previously demonstrated that some nucleotide combinations increased GFP expression up to four orders of magnitude. While it is clear that the codon region from positions 3 to 5 can influence protein expression levels of artificial constructs, its impact on endogenous proteins is still unknown. Through bioinformatics analysis, we identified the nucleotide combinations of the GFP library in Escherichia coli genes and examined the correlation between the expected levels of translation according to the GFP data with the experimental measures of protein expression. We observed that E. coli genes were enriched with the nucleotide compositions that enhanced protein expression in the GFP library, but surprisingly, it seemed to affect the translation efficiency only marginally. Nevertheless, our data indicate that different enterobacteria present similar nucleotide composition enrichment as E. coli , suggesting an evolutionary pressure towards the conservation of short translational enhancer sequences.
Stent-Change Therapy in Advanced Malignancies with Ureteral Obstruction (2005)

Stent-change therapy is an efficacious way to treat patients with advanced malignancies and ureteral obstruction, many of whom have a short life expectancy. All patients maintained adequate renal function to obviate dialysis. Most patients with stents in place will die before their renal function deteriorates. They may also benefit from treatment strategies designed to avoid the occurrence of frequent urinary infections.
Altered enolase in aged Turbatrix aceti results from conformational changes in the enzyme. (1980)

Young- and old-type enolases (2-phospho-D-glycerate hydrolyase, EC 4.2.1.11) from the free-living nematode Turbatrix aceti can be unfolded in 1.25 M guanidine hydrochloride and subsequently refolded with essentially a quantitative recovery. After refolding, both enolases form an identical or near-identical third type of the enzyme as determined by spectral criteria, sensitivity to heat, immunotitration, and rate of inactivation by bacterial protease. By the same criteria, the refolded enolase is closer in conformation to the native old form of the enzyme than to the young form. The results prove that young and old enolases are conformational isomers and that an in vivo transformation from young to old enzyme takes place by conformational changes without covalent modification. The process may be related to the previously demonstrated slowing of enolase turnover in T. aceti. Errors in sequence cannot be involved in the age-related alteration of the enzyme.
Supplementary Fig. S4 from Targeting a metalloprotease-PAR1 signaling system with cell-penetrating pepducins inhibits angiogenesis, ascites, and progression of ovarian cancer (2023)

Supplementary Fig. S4 from Targeting a metalloprotease-PAR1 signaling system with cell-penetrating pepducins inhibits angiogenesis, ascites, and progression of ovarian cancer
Assessment of Mach Number Correction for Sidewall Interference in Transonic Airfoil Testing (2003)

Effects of test section sidewalls have been investigated in a two-dimensional transonic wind tunnel. The facility has recently been modie ed to improvethe e ow two dimensionality for airfoil testing. A procedure where two Mach number corrections for top and bottom wall interference and for sidewall interference are combined is applied to data obtained in the modie ed facility. Corrected data for two different airfoils are compared with free-air computations and other experimental results, and satisfactory agreement is observed when a proper correction for sidewall effects is selected. Sidewall correction methods proposed are then applied to various cone gurations of airfoil model. Itis foundthat theapplicability depends on theratio oftestsection heighttoairfoil chord ratherthan model aspect ratio for the range of aspect ratio tested. To reduce three-dimensional effects, a device for removing sidewall boundary layers has been installed upstream of the model. The reduction of the boundary-layerthickness by the device, however, has no effect on Mach number correction, and the signie cant usefulness of the device has not been determined. These results suggest that the optimum experimental arrangement for transonic airfoil testing should be reconsidered for each wind tunnel to provide truly two-dimensional data.
ChemInform Abstract: Novel α‐Amino Acid‐Based Hydroxamic Acid Ligands for Vanadium‐Catalyzed Asymmetric Epoxidation of Allylic Alcohols. (2001)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Chapter 5. Loop Parallelization Algorithms (2001)

Summary. This chapter is devoted to a comparative survey of loop parallelization algorithms. Various algorithms have been presented in the literature, such as those introduced by Allen and Kennedy, Wolf and Lam, Darte and Vivien, and Feautrier. These algorithms make use of different mathematical tools. Also, they do not rely on the same representation of data dependences. In this chapter, we survey each of these algorithms, and we assess their power and limitations, both through examples and by stating “optimality” results. An important contribution of this chapter is to characterize which algorithm is the most suitable for a given representation of dependences. This result is of practical interest, as it provides guidance for a compiler-parallelizer: given the dependence analysis that is available, the simplest and cheapest parallelization algorithm that remains optimal should be selected.
Using Stochastic Computing to Reduce the Hardware Requirements for a Restricted Boltzmann Machine Classifier (2016)

Artificial neural networks are powerful computational systems with interconnected neurons. Generally, these networks have a very large number of computation nodes which forces the designer to use software-based implementations. However, the software based implementations are offline and not suitable for portable or real-time applications. Experiments show that compared with the software based implementations, FPGA-based systems can greatly speed up the computation time, making them suitable for real-time situations and portable applications. However, the FPGA implementation of neural networks with a large number of nodes is still a challenging task.
Different mutations of the human c-mpl gene indicate distinct haematopoietic diseases (2013)

The human c-mpl gene (MPL) plays an important role in the development of megakaryocytes and platelets as well as the self-renewal of haematopoietic stem cells. However, numerous MPL mutations have been identified in haematopoietic diseases. These mutations alter the normal regulatory mechanisms and lead to autonomous activation or signalling deficiencies. In this review, we summarise 59 different MPL mutations and classify these mutations into four different groups according to the associated diseases and mutation rates. Using this classification, we clearly distinguish four diverse types of MPL mutations and obtain a deep understand of their clinical significance. This will prove to be useful for both disease diagnosis and the design of individual therapy regimens based on the type of MPL mutations.