gebhart/patrepeval huggingface dataset:
Electron Microscopy and Lac-Z Labeling (2003)

The recognition of the potential use of stem cells in the body gives immense hope for the restoration of cell function lost to degenerative disease, injury, or genetic disorders. To prove that transplanted stem cells are actually surviving and functioning, it is necessary to label them for tracking with any of several detection methods.
Cover Picture: Macromol. Chem. Phys. 4/2006 (2006)

Cover: Time‐efficient quantification of very low branch content in polyethylene using optimised melt‐state 13 C NMR under magic‐angle spinning. Concentrations of 7‐8 branches per 100 000 CH 2 groups were determined in only 13 h. Further details can be found in the article by K. Klimke, M. Parkinson, C. Piel, W. Kaminsky, H. W. Spiess, and M. Wilhelm * on page 382.
A Mendelian locus on chromosome 16 determines susceptibility to doxorubicin nephropathy in the mouse (2005)

The development of kidney disease is influenced by both genetic and environmental factors. Searching for models of glomerulopathy that display strong gene-environment interaction, we examined the determinants of anthracycline-induced nephropathy, a classic, strain-dependent experimental model applied to rodents in the past four decades. We produced three crosses derived from mice with contrasting susceptibility to doxorubicin (DOX) nephropathy and, surprisingly, we found that this widely studied model segregates as a single-gene defect with recessive inheritance. By genome-wide analysis of linkage, we mapped the trait locus to chromosome 16A1-B1 (DOXNPH locus) in all three crosses [peak logarithm of odds (lod) score of 92.7, P = 1 x 10(-65)]; this interval represents a susceptibility locus for nephropathy. Gene expression analysis indicated that susceptibility alleles at the DOXNPH locus are associated with blunted expression of protein arginine methyltransferase 7 (Prmt7) on chromosome 8, a protein previously implicated in cellular sensitivity to chemotherapeutic agents (lod = 12.4, P = 0.0001). Therefore, Prmt7 expression serves as a molecular marker for susceptibility to DOX nephropathy. Finally, increased variation in the severity of kidney disease among affected mice motivated a second genome-wide search, identifying a locus on chromosome 9 that influences the severity and progression of nephropathy (DOXmod, peak lod score 4.3, P = 0.0018). These data provide genetic and molecular characterization of a previously unrecognized Mendelian trait. Elucidation of DOX nephropathy may simultaneously provide insight into the pathogenesis of renal failure and mechanisms of cytotoxicity induced by chemotherapeutic agents.
Maternal obesity upregulates fatty acid and glucose transporters and increases expression of enzymes mediating fatty acid biosynthesis in fetal adipose tissue depots1 (2012)

Maternal nutrient restriction leads to alteration in fetal adipose tissue, and offspring from obese mothers have an increased risk of developing obesity. We hypothesized that maternal obesity increases fetal adipogenesis. Multiparous ewes (Columbia/Rambouillet cross 3 to 5 yr of age) carrying twins were assigned to a diet of 100% (Control; CON; n = 4) or 150% (Obese; OB, n = 7) of NRC maintenance requirements from 60 d before conception until necropsy on d 135 of gestation. Maternal and fetal plasma were collected and stored at -80°C for glucose and hormone analyses. Fetal measurements were made at necropsy, and perirenal, pericardial, and subcutaneous adipose tissues were collected from 7 male twin fetuses per group and snap frozen at -80°C. Protein and mRNA expression of fatty acid translocase [cluster of differentiation (CD) 36], fatty acid transport proteins (FATP) 1 and 4, insulin-sensitive glucose transporter (GLUT-4), fatty acid synthase (FASN), and acetyl-coA carboxylase (ACC) was evaluated. Fetal weight was similar, but fetal carcass weight (FCW) was reduced (P < 0.05) in OB versus CON fetuses. Pericardial and perirenal adipose tissue weights were increased (P < 0.05) as a percentage of FCW in OB versus CON fetuses, as was subcutaneous fat thickness (P < 0.001). Average adipocyte diameter was greater (P < 0.01) in the perirenal fat and the pericardial fat (P = 0.06) in OB fetuses compared with CON fetuses. Maternal plasma showed no difference (P > 0.05) in glucose or other hormones, fetal plasma glucose was similar (P = 0.42), and cortisol, IGF-1, and thyroxine were reduced (P ≤ 0.05) in OB fetuses compared with CON fetuses. Protein and mRNA expression of CD 36, FATP 1 and 4, and GLUT-4 were increased (P ≤ 0.05) in all fetal adipose depots in OB versus CON fetuses. The mRNA expression of FASN and ACC was increased (P < 0.05) in OB vs. CON fetuses in all 3 fetal adipose tissue depots. Fatty acid concentrations were increased (P = 0.01) in the perirenal depot of OB versus CON fetuses, and specific fatty acid concentrations were altered (P < 0.05) in subcutaneous and pericardial adipose tissue because of maternal obesity. In conclusion, maternal obesity was associated with increased fetal adiposity, increased fatty acid and glucose transporters, and increased expression of enzymes mediating fatty acid biosynthesis in adipose depots. These alterations, if maintained into the postnatal period, could predispose the offspring to later obesity and metabolic disease.
Numerical Investigation of Mechanical Behaviour of Nanocrystalline Copper (1998)

AbstractThe effect of grain size on the overall elastic and plastic properties of nanocrystalline materials has been evaluated using the elastoplastic finite element method. The tensile deformation behaviour of nanocrystalline copper (based on a unit cell model comprising 2–100 nm sized copper crystallites and 1nm wide grain boundaries) has been analysed. Assuming that the material is elastic-perfect plastic (because of the very fine grain size), it has been shown that the yield stress increases and the elastic modulus decreases with a decrease in grain size. These results are consistent with the reported experimental observations. This analysis can be used effectively to predict the mechanical behaviour of any type of nanocrystalline material. PM/0752
A Design of CMOS Analog Front-End for PLC (2007)

This paper presents a full-CMOS single-chip PHY IC for Power Line Communication (PLC) systems. To achieve the low power operation and the low cost, the analog front-end is designed with full-CMOS 0.25㎛ technology. In the Rx part, the Pre-Amp and Programmable Gain Amplifier (PGA) is designed to have a wide dynamic range and gain control range because the signal from the power line is variable depending on the distance. In the Tx part, the proposed Line Driver can drive the power line without external driving circuits composed of BJT and diode device. This chip is fabricated with 0.25㎛ CMOS technology, and the die area is 3.2㎜ × 3.2㎜. The power consumption is 25㎽ at 3.0V supply voltage in Rx mode, and 325㎽ at Tx mode, respectively.
Alignment of cholesteric liquid crystals using periodic anchoring (1999)

Previous work has shown that when short-pitch cholesteric liquid crystals are aligned in cells with the helical axis in the plane of the substrate in a well-defined direction, then application of an electric field across the cells may result in microsecond in-plane switching due to the flexoelectric effect. Moreover, the response to the electric field is linear and temperature independent. Hence this device geometry has great potential since fast, temperature-independent switching with analogue gray scale may be realized. Up to now, however, the alignment of the helix in the plane of the substrate achieved, for example, by rubbed polyimide layers has been rather unstable, since it relaxes to a Grandjean texture in a time scale determined by the cell thickness. This time is generally of the order of minutes. Here we report a method for the attainment of stable anchoring of the unidirectional lying helix texture using periodic anchoring conditions.
One-Pot Esterification and Amide Formation via Acid-Catalyzed Dehydration and Ritter Reactions (2014)

Esterification of carboxylic acid is achieved using acetonitrile as a water trap. Water liberated during esterification is consumed in cyanide hydrolysis, thereby driving the esterification to completion. Substrates having carboxylic acid and nitrile groups undergo intramolecular dehydration and rehydration to amido esters in the absence of acetonitrile. Cyano acids also undergo esterification and Ritter reaction in one pot when excess alcohol is used. For the first time, we have observed an interesting Ritter reaction of primary alcohols, leading to ester amide product in one pot. [Supplementary materials are available for this article. Go to the publisher's online edition of <i>Synthetic Communications</i>® for the following free supplemental resource(s): Full experimental and spectral details.]
Improved Stability of Unsealed Quasi-Solid-State Dye-Sensitized Solar Cell Using Poly(3,4-Ethylenedioxythiophene) Film as Layer Electrolyte (2010)

Quasi-solid/solid polymer electrolytes have been the subject of extensive research for an alternative of liquid electrolyte for dye-sensitized solar cells (DSSCs) because of their advantages such as alleviated leakage, lower environmental impact and ease of device fabrication. In this work, the performance of the unsealed quasi-solid-state DSSCs based on composite poly (ethylene oxide) (PEO) electrolyte and N719 dye-sensitizer was examined on aging under atmospheric condition. The energy conversion efficiency of DSSC using the composite PEO electrolyte was 5.62 % under sun simulated light, AM 1.5 (100 mW cm-2) but gradually decreased to 0.95 % on aging for 90 days. An additional layer of poly(3,4-ethylenedioxythiophene) (PEDOT) electrolyte was incorporated with the composite polymer electrolyte for DSSC fabrication. The PEDOT layer was prepared by electrochemical polymerization of bis-ethylenedioxythiophene (bis-EDOT) and characterized by Raman spectroscopy and cyclic voltammetry. It was found that the energy conversion efficiency of DSSC based on the composite polymer electrolyte incorporated with PEDOT layer was 5.57 % and gradually decreased to 1.76 % under the same aging condition. Thus an additional layer of PEDOT electrolyte provided an improved stability of DSSC.
Influence of the sample position in compensated scanning calorimeters (1978)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTInfluence of the sample position in compensated scanning calorimetersStanislaw L. Randzio and Stig. SunnerCite this: Anal. Chem. 1978, 50, 6, 704–707Publication Date (Print):May 1, 1978Publication History Published online1 May 2002Published inissue 1 May 1978https://pubs.acs.org/doi/10.1021/ac50027a012https://doi.org/10.1021/ac50027a012research-articleACS PublicationsRequest reuse permissionsArticle Views42Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Magnetotransport in the double-atomic-layer rect-7×3-In phase on Si(111) (2023)

Magnetoresistance of the double-atomic-layer $\text{rect-}\sqrt{7}\ifmmode\times\else\texttimes\fi{}\sqrt{3}\text{-In}/\mathrm{Si}(111)$ phase was measured in situ using the four-point-probe technique in the temperature range from 2.5 to 33 K and magnetic fields from $\ensuremath{-}8$ to $+8$ T. The $\text{rect-}\sqrt{7}\ifmmode\times\else\texttimes\fi{}\sqrt{3}\text{-In}/\mathrm{Si}(111)$ was found to demonstrate a classical quadratic behavior of magnetoresistance at fields lower than $\ensuremath{\sim}0.2$ T, and a large positive linear magnetoresistance at fields up to 8 T in the low-temperature range of up to $\ensuremath{\sim}10$ K. In contrast, the results obtained on the parent single- and double-atomic In layers formed on the ${\mathrm{NiSi}}_{2}/\text{Si}(111)$ substrate show much lower values of magnetoresistance. In view of the density functional theory calculation results, which reveal the presence of tiny Fermi pockets in the $\text{rect-}\sqrt{7}\ifmmode\times\else\texttimes\fi{}\sqrt{3}\text{-In/Si}(111)$ electronic band structure, we attribute the observed large linear magnetoresistance at the low-temperature range to a quantum mechanical origin.
Biological Control Potential and Drawbacks of Three Zoophytophagous Mirid Predators against Bemisia tabaci in the United States (2020)

Miridae (Hemiptera) of the tribe Dicyphini are important zoophytophagous predators use to control pest arthropods in vegetable crops. However, the risk that their herbivory may cause economic damage could hinder their application as useful biocontrol agents and may limit the likelihood they would meet regulatory requirements for importation. We conducted field cage studies to assess the predation capacity and tomato plant damage of three mirid species established in south USA, a known biocontrol agent (<i>Nesidiocoris tenuis</i>), and two native species (<i>Macrolophus praeclarus</i> and <i>Engytatus modestus</i>). All three species significantly reduced the number of whiteflies (<i>Bemisia tabaci</i>) on tomato plants compared to tomato plants without mirids. More damage, evaluated as the number of necrotic rings, was observed on tomato plants with <i>E. modestus</i> and <i>N. tenuis</i> compared to <i>M. praeclarus.</i> In our experiments that included sesame plants (<i>Sesamum indicum</i>) with tomato plants, mirid numbers increased despite a low number of prey, thus showing a benefit of the plant-feeding habit of these predators. USA's established mirids may therefore prove to be immediately available biological agents for the management of present and future tomato pests.
Supplementary Table 1, Supplementary Table 2, Supplementary Table 3, or Supplementary Table 4 from Prognostic Impact of <i>IL6</i> Genetic Variants in Patients with Metastatic Colorectal Cancer Treated with Bevacizumab-Based Chemotherapy (2023)

&lt;p&gt;Supplementary Table 1. Associations between baseline characteristics and clinical outcomes in the training cohort (TRIBE) Supplementary Table 2. Associations between baseline characteristics and clinical outcomes in the validation cohort (FIRE-3) Supplementary Table 3. Associations between baseline characteristics and clinical outcomes in the control cohort (FIRE-3) Supplementary Table 4. Association between IL-6, STAT3 SNPs with clinical outcomes in the training cohort&lt;/p&gt;
Heuristic risk assessment using cost factors (1997)

The author describes an expert system tool that can be used to analyze patterns of software cost driver ratings submitted for a Cocomo cost estimate. These results help users determine and rank associated sources of software project risk.
N- and O-Glycosylation in the Murine Synaptosome (2013)

We present the first large scale study characterizing both N- and O-linked glycosylation in a site-specific manner on hundreds of proteins. We demonstrate that a lectin-affinity fractionation step using wheat germ agglutinin enriches not only peptides carrying intracellular O-GlcNAc, but also those bearing ER/Golgi-derived N- and O-linked carbohydrate structures. Liquid chromatography-MS (LC/MS) analysis with high accuracy precursor mass measurements and high sensitivity ion trap electron-transfer dissociation (ETD) were utilized for structural characterization of glycopeptides. Our results reveal both the identity of the precise sites of glycosylation and information on the oligosaccharide structures possible on these proteins. We report a novel iterative approach that allowed us to interpret the ETD data set directly without making prior assumptions about the nature and distribution of oligosaccharides present in our glycopeptide mixture. Over 2500 unique N- and O-linked glycopeptides were identified on 453 proteins. The extent of microheterogeneity varied extensively, and up to 19 different oligosaccharides were attached at a given site. We describe the presence of the well-known mucin-type structures for O-glycosylation, an EGF-domain-specific fucosylation and a rare O-mannosylation on the transmembrane phosphatase Ptprz1. Finally, we identified three examples of O-glycosylation on tyrosine residues.
Joint Access Control and Resource Allocation for mMTC based on Tagged Preamble (2019)

In this paper, we investigate the access control and resource allocation for mMTC based on tagged preamble (PA). Through two detection of tagged PA at base station, MTC device can be further distinguished in RA process. Then, optimization problem concerning joint access class barring parameter and tag number for each area is formulated, which aims as maximizing the throughput of the cell. To solve this optimization problem, we decompose the original problem and deal with it in two steps, first we can obtain a closed expression of the optimal ACB parameters for each area. In the second step, we propose a “class waterfilling” algorithm to optimize the number of tags in each area. Simulation results show that dynamic tag allocation and ACB factor adjustment can increase the access success probability of the random access process and reduce the average access delay.
Pulmonary medicine and (adult) critical care medicine in Europe: Fig. 1.— (2002)

There has been growing concern within the European Respiratory Society (ERS) that pulmonary physicians are becoming less involved in the practise of intensive care medicine (ICM). A Working Party (WP) was therefore established to identify issues that might explain this trend. No precise terms of reference were issued to guide this exercise. The WP ensured that its report focussed on improving patient care. With this proviso, the WP aimed to: 1) briefly identify the current working practices of pulmonary physicians practicing ICM in six European Union (EU) countries (France, Germany, Greece, Italy, Spain and UK); 2) discuss possible opportunities to expand the influence of pulmonary physicians in the provision of acute care; and 3) determine the implications of 1) for training programmes.

The following methods were employed. 1) Relevant literature was extracted and a draft report concerning the three points discussed previously was prepared and circulated to the members of the WP. 2) A 1-day meeting was held in Paris on March 26th, 2001, and the contents of the draft report discussed and refined. 3) A second draft was prepared and circulated. 4) A final report was forwarded to the executives of the ERS.

In Europe, ICM is one of the most recent clinical disciplines to evolve. The polio epidemic in Denmark in 1952 showed that careful airway management with the application of positive pressure ventilation could dramatically reduce mortality in patients who presented with paralysis of the respiratory muscles. This focus on airway care and ventilatory management encouraged anaesthesiologists to lead the way in the introduction of critical care facilities. Technological advances in the 1960s led to the development of sophisticated physiological monitoring equipment. The subsequent recognition that the diagnosis and management of critical illness required additional skills to those incorporated into training in anaesthesiology, attracted clinicians trained in …
A Cramer-Shoup Encryption Scheme from the Linear Assumption and from Progressively Weaker Linear Variants. (2007)

We describe a CCA-secure public-key encryption scheme, in the Cramer-Shoup paradigm, based on the Linear assumption of Boneh, Boyen, and Shacham. Through a comparison to the Kiltz tag-encryption scheme from TCC 2006, our scheme gives evidence that the Cramer-Shoup paradigm yields CCA encryption with shorter ciphertexts than the Canetti-Halevi-Katz paradigm. We present a generalization of the Linear assumption into a family of progressively weaker assumptions and show how to instantiate our Linear Cramer-Shoup encryption using the progressively weaker members of this family.
TEMPORAL TRENDS IN RATES OF PROSTATE CANCER: DECLINING INCIDENCE OF ADVANCED STAGE DISEASE, 1974 TO 1994 (1997)

The incidence rate of prostate cancer in the Seattle-Puget Sound region is higher than the rate in some other regions of the country. This is likely due to widespread, more intense prostate specific antigen screening of the population in this region compared to other areas of the country. The incidence rate of prostate cancer in the Seattle-Puget Sound region has peaked and is now declining.
Physical Separations of Rare Earth Elements from Coal and Coal By-Products (2021)

Presented by NETL at ACS National Meeting, 3/18
Current-Controlled, High-Speed Magneto-Optic Switching (2010)

In this paper, an optical switch utilizing a magneto-optic Faraday rotator (MOFR) capable of submicrosecond switching is presented. The optical circuit and supporting electronic circuitry are presented. High optical switching speeds are accomplished through the design of an electronic circuit capable of creating high-speed magnetic pulses. Rise times of 75 ns of 40-Oe magnetic fields are achieved for optical circuit control. Experimental results of the electrical and optical circuit are presented. Circuit design and practical considerations are discussed.
To new beginnings and a better alternative (2015)

David M. Cwiertny, Editor-in-Chief of <italic>Environmental Science: Water Research &amp; Technology</italic>, introduces the inaugural issue.
Bone turnover in postmenopausal osteoporosis. Effect of calcitonin treatment. (1988)

(a) assessment of bone turnover cannot help predict the severity of bone loss in postmenopausal osteoporosis; (b) calcitonin therapy appears to be particularly indicated for patients with high-turnover osteoporosis, resulting in a net gain of bone mineral in the axial skeleton and a slowing of bone loss in the appendicular bones.
DEVELOPMENTALLY REGULATED GENE REARRANGEMENTS IN PROKARYOTES (1992)

Orthologs and paralogs are two fundamentally different types of homologous genes that evolved, respectively, by vertical descent from a single ancestral gene and by duplication. Orthology and paralogy are key concepts of evolutionary genomics. A ...Read More
Array and diversity gains of an RF-AAA used on MIMO receiver (2003)

We implemented an RF-adaptive array antenna (RF-AAA) on a multiple-input multiple-output (MIMO) receiver using Alamouti’s scheme. A new criterion maximizing the squared Frobenius norm of the MIMO channel matrix is proposed for controlling the RF-AAA. Computer simulation showed that a 2× 2 MIMO system with a 2-element RF-AAA implemented using Alamouti’s scheme provided an array and a greater diversity gain and lower bit error rate (BER) performance than a 2 × 4 MIMO system with maximum likelihood decoding (MLD) in both low and high correlation scenarios with MIMO channels.