gebhart/patrepeval huggingface dataset:
Photochemically generated cytosolic calcium pulses and their detection by fluo-3 (1989)

Fluo-3, one member of a family of new fluorescent Ca2+ indicators excitable at wavelengths in the visible (Minta, A., Kao, J. P. Y., and Tsien, R. Y. (1989) J. Biol. Chem. 264, 8171-8178), has been tested in living cells. We demonstrate that fluo-3 can be loaded into fibroblasts and lymphocytes by incubation with the pentaacetoxymethyl ester of the dye and that the ester is hydrolyzed intracellularly to yield genuine fluo-3 capable of indicating changes in [Ca2+]i induced by agonist stimulation. Fluo-3 can also be microinjected into fibroblasts along with photolabile compounds such as nitr-5 and caged inositol trisphosphate for photorelease experiments. Fluo-3 permits continuous monitoring of [Ca2+]i without interference with use of UV-sensitive caged compounds. A procedure for combined use of ionophore and heavy metal ions in end-of-experiment calibration of fluo-3 intensities to give [Ca2+]i is also described.
High-Capacity Lithium–Air Cathodes (2008)

Lithium–oxygen (air) has one of the largest theoretical energy densities of any practical electrochemical couple. This paper discusses the architecture of an advanced Li–air cathode with an average voltage of and a gravimetric capacity of of carbon, achieved at (i) a current density of and (ii) without the use of catalysts.
Agents Affecting Lipid Metabolism. XXI. Miscellaneous Compounds Related to trans-1,4-Bis(2-chlorobenzylaminomethyl)cyclohexane1 (1966)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAgents Affecting Lipid Metabolism. XXI. Miscellaneous Compounds Related to trans-1,4-Bis(2-chlorobenzylaminomethyl)cyclohexane1Leslie G. HumberCite this: J. Med. Chem. 1966, 9, 3, 441–443Publication Date (Print):May 1, 1966Publication History Published online1 May 2002Published inissue 1 May 1966https://pubs.acs.org/doi/10.1021/jm00321a055https://doi.org/10.1021/jm00321a055research-articleACS PublicationsRequest reuse permissionsArticle Views57Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Backward predictive block matching algorithm for low bit rate video coding (1991)

In contrast to the conventional block matching algorithm (BMA) in video coding, a backward predictive BMA which does not need the transmission of the motion vector is investigated. The motion vector is estimated using the previously estimated motion vectors and reconstructed pixels adjacent to a block to be coded. For application to low bit rate video coding, backward/forward adaptive BMA is devised. At 59kbit/s the proposed scheme provides 0.2–0.5dB improvement in peak signal to noise ratio (PSNR) over the conventional BMA.
[Pes anserinus transfer and medial transplantation of the tibial tubercle in the treatment of rotary instability of the knee (author's transl)]. (1980)

23 cases of rotary instability of the knee have been reviewed with an average follow up of 5 years. They have been treated by a combination of pes anserinus transfer using Slocum's technique with medial transposition of the tibial tubercle. Functionally the results were satisfactory and there was no antero-posterior instability. No secondary patello-femoral arthrosis was seen. All the knees seemed to be more stable but most cases showed some degree of effusion, quadriceps wasting and some pain. It is concluded that this type of surgical procedure may provide a satisfactory knee for lighter sporting activities but not for competitive sport.
Diffusion of Neptunium(V) in Clays (1990)

International audience
Beam combination with a large number of apertures (2010)

Mozurkewich presented a beam combiner design suitable for use with a large number of apertures. Such a system has applications both in space and as a camera for single-aperture, ground-based telescopes. We implemented a version of this design which accommodates ~ 90 apertures and resolves the fringes into more than 100 spectral channels. The resulting system, which has been tested in the laboratory, provides over 50,000 simultaneous, independent fringe measurements. Implementation details and test results are presented.
Receiver operating characteristic analysis of sphincter electromyography for parkinsonian syndrome (2012)

This study suggests that duration is appropriate parameter for the differentiation of MSA. However, the area under the curve of the mean duration was insufficient to confirm the diagnosis; sphincter EMG should be used as a supportive diagnostic tool for the diagnosis of MSA.
Raman Scattering Study of Lattice Vibrations in the Type-II Superlattice InAs/InAs1−xSbx (2017)

InAs/In(As,Sb) type-II superlattices are of increasing interest for their practical advantages in device applications, particularly IR detection. This comparative study of highest-quality superlattices grown by different techniques and groups establishes the utility of Raman spectroscopy as an efficient, nondestructive technique for characterizing these systems. It also provides a unified understanding of the mechanism of the appearance of forbidden optical-phonon modes in four quite different categories of superlattices, and even bulk alloys with unintended structural modulations.
Requirements and Technological Needs for Military Space-borne Reconnaissance Systems (2010)

Requirements&#13;\nFor military space-borne reconnaissance systems two major requirements are minimized systems response time, which is the time span between the order of a needed image and an assessable image on ground, and minimized image age, which is the time span between image acquisition and assessable image on ground.&#13;\nTo fulfil these requirements in an optimal way with reasonable image quality and cost, a constellation of small satellites is needed.&#13;\n&#13;\nSoftware&#13;\nFor design, development and operations of such a multi satellite mission new software tools are necessary. The regarding developments within the Satellite-Systems-Engineering Group of DLR will be presented.&#13;\n&#13;\nHardware&#13;\nAlso new hardware technologies are needed to build up a cost effective satellite constellation. The possibility for multiple launches is a cost saver but requires small satellites and therefore, using a classical SAR-Sensor for image generation, deployable reflectors to get reasonable apertures in space. A proposal for such a new reflector technology will be presented.&#13;\n&#13;\nRisk analysis&#13;\nThe more satellites we have in space the larger is the risk for the single space craft to be damaged or destroyed by natural, man-made or active threats in orbit. The possible threats will be shortly overviewed and potential counteractions described.&#13;\n
Effects of Selected Secondary Metabolites in Leaf Extract of Jatropha Tanjorensis on Some Gonadal Hormones in Male Wistar Rats (2020)

Background and Objective The use of medicinal plants in industrialized societies for extraction and development of many drugs and other chemotherapeutics and traditionally for herbal remedies has increased in recent times. Plant–based medicine is essential in health care services with about 80% global population relying on it because of its cheap source and availability. Jatropha tanjorensis is one such plant used by males and females of childbearing age for treatment of reproductive problems such as infertility. Literature on isolation and characterization of the secondary metabolites in this plant may not be common. Against this backdrop, this research work was carried out to isolate, characterize and determine the effects of J. tanjorensis on the gonadal hormones of male wistar rats. Materials and Methods The secondary metabolites were isolated, characterized, and identified using nuclear magnetic resonance. The experiment was conducted using 25 male wistar rats weighing between 180-200 g randomized into 5 groups, 3 controls and 2 treatment groups of 5 rats each. The treatment groups received 25 mg/kg body weight of phytol and lupeol orally by gastric lavage for 14 days. The animals were anaesthetized and blood samples collected for hormonal assay. Result The experimental data was analyzed using one-way analysis of variance (ANOVA) with Statistical Package for Social Sciences (SPSS) version 17.0, while the post hoc test assessed using Duncan Multiple Range Test at p ≥ 0.05. There was a significant decrease (p ˂ 0.05) in the levels of FSH, LH and TST in the treatment groups when compared to the control groups. The motility and sperm count decrease significantly (p ˂ 0.05) when treatment groups were compared to the control animals. The secondary metabolites, phytol and lupeol present in the leaf extract of Jatropha tanjorensis were responsible for the decrease in some of the gonadal hormones studied.
Piezo-orbital backaction force in a rare-earth doped crystal (2021)

We investigate a system composed of an ensemble of room temperature rare-earth ions embedded in a bulk crystal, intrinsically coupled to internal strain via their sensitivity to the surrounding crystal field. We evidence the generation of a mechanical response under resonant atomic excitation. We find this motion to be the sum of two fundamental, resonant optomechanical backaction processes: a conservative, piezo-orbital mechanism, resulting from the modification of the crystal field associated with the promotion of the ions to their excited state, and a dissipative, non-radiative photothermal process related to the phonons generated throughout the atomic population relaxation. Our work opens new research avenues in hybrid optomechanics, and highlights new interactions that may be key for understanding the dephasing dynamics of ultra-coherent rare-earth ions.
Mansonella perstans— The Importance of an Endosymbiont (2009)

The prevalence of filarial infections in the tropics is second only to that of geohelminth (soil-transmitted helminth) infections. Filarial infections in humans include the various forms of lymphatic filariasis (Wuchereria bancrofti, Brugia malayi, and B. timori), onchocerciasis (Onchocerca volvulus), loiasis (Loa loa), and mansonellosis (Mansonella streptocerca, M. perstans, and M. ozzardi).About 120 million people currently have lymphatic filariasis, and about 1 billion people are considered to be at risk for infection. Lymphatic filariasis remains endemic in 81 countries and is prevalent on all continents except Australia. Approximately 37 million people have . . .
Plasma Nitriding and DLC Coatings for Corrosion Protection of Precipitation Hardening Stainless Steel (2015)

A duplex treatment, combining a nitriding diffusion process and the deposition of DLC coatings is investigated as an option for corrosion protection of precipitation hardening steels, in order to increase the service life of components used in plastic injection molds. Hardness and mechanical resistance are determined and the corrosion resistance in two different media is analyzed. Non‐coated nitrided and non‐nitrided samples are also tested for comparison. Corrosion resistance is investigated by means of immersion, salt spray, and polarization tests. No signs of atmospheric corrosion are observed after the salt spray test and in acid media, the nitrided samples, with and without DLC, present the lowest mass loss. The duplex sample shows the best corrosion behavior in the electrochemical tests.
Heat Transfer Measurements in an Annular Cascade of Transonic Gas Turbine Blades Using the Transient Liquid Crystal Technique (1994)

Heat transfer measurements have been made in the Oxford University Cold Heat Transfer Tunnel employing the transient liquid crystal technique. Complete contours of the heat transfer coefficient have been obtained on the aerofoil surfaces of a large annular cascade of high pressure nozzle guide vanes (mean blade diameter of 1.11 m and axial chord of 0.0664 m). The measurements are made at engine representative Mach and Reynolds numbers (exit Mach number 0.96 and Reynolds number 2.0 × 106). A novel mechanism is used to isolate five preheated blades in the annulus before an unheated flow of air passes over the vanes, creating a step change in heat transfer. The surfaces of interest are coated with narrow-band thermochromic liquid crystals and the colour crystal change is recorded during the run with a miniature CCD video camera. The heat transfer coefficient is obtained by solving the one dimensional heat transfer equation for all the points of interest. This paper will describe the experimental technique and present results of heat transfer and flow visualisation.
Is Chlamydophila felis a significant zoonotic pathogen? (2004)

While there is evidence that C. felis may occasionally cause keratoconjunctivitis in humans, there is little evidence to suggest it can cause serious systemic disease or pneumonia.
Scattering camouflage and manipulation using metasurfaces (2016)

In this contribution, we propose the use of metasurfaces not only to cloak an object but also to change its scattering response in view of camouflage and scattering manipulation applications. We present the analytical formulation for the case of a cylindrical object with the goal of deriving the surface impedance of the surrounding metasurface to make the object appearing as it were either larger or thinner. We find that not all the camouflage cases can be achieved by using only passive metasurfaces and active components may be required. The analytical and numerical results are discussed, in view of possible actual applications.
Passivity-Based Analysis and Performance Enhancement of a Vector Controlled VSC Connected to a Weak AC Grid (2020)

Despite attempts to increase the active power capability of vector-controlled voltage source converters (VSCs) connected to very weak grids, the interaction between the control dynamics and physical system is not completely understood. The result is often complex strategies that are difficult to implement. This paper proposes an intuitive modification of the VSC control based on physical considerations and dynamics of existing control. Several physical variables as seen from the point of common coupling (PCC) are found to contribute to the detrimental behavior of the VSC under weak connections. Hence, eliminating the impacts of these variables through feedforward eliminates their influence and significantly improves the active power capability. Notably, the basic structure of the vector controlled VSC is kept and its output-impedance is effectively reshaped. The proposed modification is validated through nonlinear time-domain simulations in MATLAB/Simulink Simscape Power System and results demonstrate the simplicity and intuitiveness of the modified structure.
Iron testes: sperm mitochondria as a context for dissecting iron metabolism (2010)

A recent paper in BMC Developmental Biology reports that a mitochondrial iron importer is required for Drosophila male fertility and normal mitochondrial shaping in spermatids. This suggests that mitochondrial morphogenesis during insect spermatogenesis may be a useful new context in which to study iron metabolism. See research article http://www.biomedcentral.com/1471-213X/10/68.
Recursive Parametric Tests for Multichannel Adaptive Signal Detection (2006)

The parametric Rao and generalized likelihood ratio test (GLRT) detectors, recently developed by exploiting a multi channel autoregressive (AR) model for the disturbance, has been shown to perform well with very limited or no training data. The AR model order, however, should be estimated by some model order selection technique. Standard non-recursive implementation of the parametric detectors is computationally intensive, since the parameters have to be estimated for each possible model order. This paper presents recursive versions of the parametric detectors using the multichannel Levinson algorithm, which is used to recursively solve the multi channel Yule-Walker equations and find parameter estimates used by these detectors. Estimation of the AR model order can also be naturally integrated since the multichannel Levinson algorithm yields parameter estimates at every recursion (i.e., for every AR model order). Numerical results show that the proposed recursive parametric tests that assume no knowledge about the model order perform quite close to the corresponding non-recursive parametric detectors at reduced computational complexity, even though the latter requires exact knowledge of the model order
Big Data for a Big Problem: Precision Medicine of Stroke in Neurocritical Care* (2018)

Neurovascular Imaging Research Core and UCLA Stroke Center, Department of Neurology, University of California, Los Angeles, CA *See also p. 1085. Dr. Liebeskind disclosed that he is a consultant to Stryker and Medtronic as Imaging and Angiography Core Laboratory for endovascular stroke trials in acute ischemic stroke, and he is employed by the University of California, which holds a patent on endovascular devices for stroke treatment.
Aging-related Changes in Mouse Serum Glycerophospholipid Profiles (2014)

The ratios of the individual metabolites PC and LPC could serve as potential biomarkers for aging and aging-related diseases.
Learning text classifier using the domain concept hierarchy (2003)

Automatic text categorization is an important component in many information organization and management tasks. Research has shown that similarity based categorization algorithms like K-nearest neighbour (KNN) are effective in document categorization. These algorithms use index terms to represent documents. However some drawbacks persecute these algorithms. One major drawback is that they tend to use all features when computing the similarities, which implies that they must search in a high-dimensional space. Another major drawback is that they tend to use a very large training document set so that all terms, which are important to identify content of documents, are covered. To overcome these drawbacks, in this paper, we present a novel method to search for the optimal representation in a domain ontology hierarchical structure to reflect concepts for the taxonomic standard for pre-defined categories. Experiments have shown this is a feasible method to reduce the dimensionality of the document vector space effectively and reasonably and consequently improves the generalisation power of the derived classifier. The result is a classification method which is both very significantly less costly, in computation terms, and yet of considerably higher accuracy than comparable methods.
Sound source separation in monaural music signals using excitation-filter model and em algorithm (2010)

This paper proposes a method for separating the signals of individual musical instruments from monaural musical audio. The mixture signal is modeled as a sum of the spectra of individual musical sounds which are further represented as a product of excitations and filters. The excitations are restricted to harmonic spectra and their fundamental frequencies are estimated in advance using a multipitch estimator, whereas the filters are restricted to have smooth frequency responses by modeling them as a sum of elementary functions on Mel-frequency scale. A novel expectation-maximization (EM) algorithm is proposed which jointly learns the filter responses and organizes the excitations (musical notes) to filters (instruments). In simulations, the method achieved over 5 dB SNR improvement compared to the mixture signals when separating two or three musical instruments from each other. A slight further improvement was achieved by utilizing musical properties in the initialization of the algorithm.
Draft genome of six Cuban Anolis lizards and insights into genetic changes during the diversification (2022)

Abstract The detection of various type of genomic variants and their accumulation processes during species diversification and adaptive radiation is important for understanding the molecular and genetic basis of evolution. Anolis lizards in the West Indies are good models for studying the mechanism of the evolution because of the repeated evolution of their morphology and the ecology. In this study, we performed de novo genome assembly of six Cuban Anolis lizards with different ecomorphs and thermal habitats ( Anolis isolepis, Anolis allisoni, Anolis porcatus, Anolis allogus, Anolis homolechis , and Anolis sagrei ). As a result, we obtained six novel draft genomes with relatively long and high gene completeness, with scaffold N50 ranging from 5.56–39.79 Mb, and vertebrate Benchmarking Universal Single-Copy Orthologs completeness ranging from 77.5% to 86.9%. Subsequently, we performed comparative analysis of genomic contents including those of mainland Anolis lizards to estimate genetic variations that had emerged and accumulated during the diversification of Anolis lizards. Comparing the repeat element compositions and repeat landscapes revealed differences in the accumulation process between Cuban trunk-crown and trunk-ground species, LTR accumulation observed only in A. carolinensis , and separate expansions of several families of LINE in each of Cuban trunk-ground species. The analysis of duplicated genes suggested that the proportional difference of duplicated gene number among Cuban Anolis lizards may be associated to the difference of their habitat range. Furthermore, Pairwise Sequentially Markovian Coalescent analysis proposed that the effective population sizes of each species might have been affected by Cuba’s geohistory. Hence, these six novel draft genome assemblies and detected genetic variations can be a springboard for the further genetic elucidation of the Anolis lizard’s diversification. Significance Anolis lizard in the West Indies is excellent model for studying the mechanisms of speciation and adaptive evolution. Still, due to a lack of genome assemblies, genetic variations and accumulation process of them involved in the diversification remain largely unexplored. In this study, we reported the novel genome assemblies of six Cuban Anolis lizards and analyzed evolution of genome contents. From comparative genomic analysis and inferences of genetic variation accumulation process, we detected species- and lineage-specific transposon accumulation processes and gene copy number evolution, considered to be associated with the adaptation to their habitats. Additionally, we estimated past effective population sizes and the results suggested its relationship to Cuba’s geohistory.
Recent improvements to the PROSITE database (2003)

The PROSITE database consists of a large collection of biologically meaningful signatures that are described as patterns or profiles. Each signature is linked to documentation that provides useful biological information on the protein family, domain or functional site identified by the signature. The PROSITE web page has been redesigned and several tools have been implemented to help the user discover new conserved regions in their own proteins and to visualize domain arrangements. We also introduced the facility to search PDB with a PROSITE entry or a user's pattern and visualize matched positions on 3D structures. The latest version of PROSITE (release 18.17 of November 30, 2003) contains 1676 entries. The database is accessible at http://www.expasy.org/prosite/.