gebhart/patrepeval huggingface dataset:
Network management in ATM LEO satellite networks (2003)

Development of the past decade have confirmed that ATM technology has the potential of becoming the transport mechanism in many multimedia networks where high-speed traffic and Quality of Service guarantees must be provided. More recently, we have witnessed a surge of interest in Low Earth Orbiting (LEO) satellite networks with on-board ATM switches, which hold the promise of offering an economically viable extension of terrestrial ATM systems by providing connectivity to areas where existing terrestrial networks are either infeasible or impractical. Network management in ATM LEO satellite networks is typically performed by the Network Control Center (NCC). The main contribution of this paper is to examine basic NCC requirements, to propose a Network Management System architectural configuration with a stand-by solution, to investigate the NCC protocol stack, and to describe an experimental satellite Management Information Base (SMIB) that we have developed for implementation in ATM LEO satellite networks.
Double Wye Modular Multilevel Converter - Direct DC-DC Topology (2016)

Modular Multilevel Converter (MMC) topology starts to be more and more popular in various power electronic applications. The main reason of increased popularity of MMC is demonstrating of advantages over other traditional topologies. The key benefit of modular approach is observed especially in easy scaling of the converter voltage and simple implementation of redundancy. Existing MMC topologies include different variants of solutions. The most applicable are: AC-DC and direct AC-AC, delta and wye connections. Less frequently analysed is DC-DC conversion, realised with intermediate AC link incorporating magnetic components. In this publication the new double wye direct DC-DC topology is introduced and discussed.
Regulation of Inflammatory Phenotype in Macrophages by a Diabetes-Induced Long Noncoding RNA (2014)

The mechanisms by which macrophages mediate the enhanced inflammation associated with diabetes complications are not completely understood. We used RNA sequencing to profile the transcriptome of bone marrow macrophages isolated from diabetic db/db mice and identified 1,648 differentially expressed genes compared with control db/+ mice. Data analyses revealed that diabetes promoted a proinflammatory, profibrotic, and dysfunctional alternatively activated macrophage phenotype possibly via transcription factors involved in macrophage function. Notably, diabetes altered levels of several long noncoding RNAs (lncRNAs). Because the role of lncRNAs in diabetes complications is unknown, we further characterized the function of lncRNA E330013P06, which was upregulated in macrophages from db/db and diet-induced insulin-resistant type 2 diabetic (T2D) mice, but not from type 1 diabetic mice. It was also upregulated in monocytes from T2D patients. E330013P06 was also increased along with inflammatory genes in mouse macrophages treated with high glucose and palmitic acid. E330013P06 overexpression in macrophages induced inflammatory genes, enhanced responses to inflammatory signals, and increased foam cell formation. In contrast, small interfering RNA-mediated E330013P06 gene silencing inhibited inflammatory genes induced by the diabetic stimuli. These results define the diabetic macrophage transcriptome and novel functional roles for lncRNAs in macrophages that could lead to lncRNA-based therapies for inflammatory diabetes complications.
Luminescent Coupling in GaAs/GaInNAsSb Multijunction Solar Cells (2012)

Multijunction subcell short-circuit currents are typically calculated by integrating the product of the external quantum efficiency and the input solar irradiance. The actual subcell current can be much greater than the result of this calculation when luminescence from a high bandgap subcell couples into a lower bandgap subcell. A model is developed, based on detailed balance, which quantifies luminescent coupling current under different spectral conditions. Steady-state laser and pulsed flash measurements on GaAs/GaInNAsSb dual-junction solar cells demonstrate a luminescent coupling factor of ~35%, compared with the theoretical maximum value of ~48%. The deviation from maximum is due to nonradiative current in the GaAs subcell.
A pedigree series for mapping disease genes in bipolar affective disorder (1994)

A series of 57 extended pedigrees with high density of bipolar affective disorder is described. Ascertainment and diagnostic procedures are documented and simulation studies to assess statistical power are carried out. The pedigrees, obtained in the US and Israel, are comprised of 1508 adult individuals with best estimate consensus diagnoses (12-71 relatives per pedigree), 490 of whom (including 401 sib pairs) meet criteria for a conservative disease definition (bipolar disorder or recurrent major depression). Cell lines have been established on 1324 of these individuals. Statistical power to detect linkage with lod score analysis, assuming autosomal dominant transmission and highly polymorphic DNA markers, is nearly 100% for alpha (proportion of linked families) = 30%, and 75% for alpha = 20%. This is the largest bipolar pedigree series reported to date; its unique features make it amenable to various gene detection techniques.
Radiation resistant erbium doped fiber for ASE source and fiber gyroscope application (2017)

A radiation resistant optical fiber used in a broadband source is presented. Both ASE source and Fiber Optical Gyroscope (FOG) commonly used in space missions, suffer from failures and degradation after long term exposure to radiative environment. The aim of this article is to present the results of our investigation on fiber and ASE source architecture in order to design a Radiation Resistant Erbium Doped Fiber that offers long term stability of the gyroscope performances.
Inferring Human Observer Spectral Sensitivities from Video Game Data (2020)

With the use of primaries which have increasingly narrow bandwidths in modern displays, observer metameric breakdown is becoming a significant factor. This can lead to discrepancies in the perceived color between different observers. If the spectral sensitivity of a user's eyes could be easily measured, next generation displays would be able to adjust the display content to ensure that the colors are perceived as intended by a given observer. We present a mathematical framework for calculating spectral sensitivities of a given human observer using a color matching experiment that could be done on a mobile phone display. This forgoes the need for expensive in-person experiments and allows system designers to easily calibrate displays to match the user's vision, in-the-wild. We show how to use sRGB pixel values along with a simple display model to calculate plausible color matching functions (CMFs) for the users of a given display device (e.g., a mobile phone). We evaluate the effect of different regularization functions on the shape of the calculated CMFs and the results show that a sum of squares regularizer is able to predict smooth and qualitatively realistic CMFs.
Selective histone deacetylase (HDAC) inhibition imparts beneficial effects in Huntington's disease mice: implications for the ubiquitin–proteasomal and autophagy systems (2012)

We previously demonstrated that the histone deacetylase (HDAC) inhibitor, 4b, which preferentially targets HDAC1 and HDAC3, ameliorates Huntington's disease (HD)-related phenotypes in different HD model systems. In the current study, we investigated extensive behavioral and biological effects of 4b in N171-82Q transgenic mice and further explored potential molecular mechanisms of 4b action. We found that 4b significantly prevented body weight loss, improved several parameters of motor function and ameliorated Huntingtin (Htt)-elicited cognitive decline in N171-82Q transgenic mice. Pathways analysis of microarray data from the mouse brain revealed gene networks involving post-translational modification, including protein phosphorylation and ubiquitination pathways, associated with 4b drug treatment. Using real-time qPCR analysis, we validated differential regulation of several genes in these pathways by 4b, including Ube2K, Ubqln, Ube2e3, Usp28 and Sumo2, as well as several other related genes. Additionally, 4b elicited increases in the expression of genes encoding components of the inhibitor of kappaB kinase (IKK) complex. IKK activation has been linked to phosphorylation, acetylation and clearance of the Htt protein by the proteasome and the lysosome, and accordingly, we found elevated levels of phosphorylated endogenous wild-type (wt) Htt protein at serine 16 and threonine 3, and increased AcK9/pS13/pS16 immunoreactivity in cortical samples from 4b-treated mice. We further show that HDAC inhibitors prevent the formation of nuclear Htt aggregates in the brains of N171-82Q mice. Our findings suggest that one mechanism of 4b action is associated with the modulation of the ubiquitin-proteasomal and autophagy pathways, which could affect accumulation, stability and/or clearance of important disease-related proteins, such as Htt.
Das Schwere Akute Respiratorische Syndrom (SARS) (2003)

The severe acute respiratory syndrome (SARS) is a highly infectious respiratory disease, to the best of our knowledge caused by a hitherto unknown corona virus. The virus has spread from South East Asia to many countries of the world. Three case reports of patients from the Prince of Wales Hospital of The Chinese University of Hong Kong demonstrate typical clinical courses. Fever, cough, in most cases non-productive, myalgia, chills, and rigor are the leading symptoms. Leucopenia and thrombocytopenia are the most prominent laboratory parameters, increased values for lactatedehydrogenase (LDH) reflect a more severe clinical course. Advanced age and coexisting conditions seem to influence the prognosis unfavourably. The chest roentgenogram may be normal initially but at a later stage progressive consolidations in the majority of peripheral parts of the lung are observed, which cannot be differentiated from pneumonias of other origin. Even young patients can enter a stage of respiratory compromise rather fast. A therapy against the cause of the disease is not known. Empirical therapy with ribavirin in combination with high dose corticosteroids have proved successful. The disease may progress into respiratory failure comparable with an acute respiratory distress syndrome (ARDS). Mortality is around five to ten per cent. Stringent hygiene and quarantine measures are mandatory to prevent the further spread of this threatening disease.
Dispersive model selection and reconstruction for tissue culture ultrasonic monitoring (2012)

The evolution of relevant mechanical parameters during tissue engineering formation processes can provide useful information for their control in real-time, as well as a new dimension in the understanding of internal processes and their final quality. Since ultrasonics are mechanical waves, they are ideally well suited for probing certain mechanical properties. An ultrasound monitoring Petri dish has been designed for this purpose. The readings from the ultrasonic sensors need a detailed analysis, based on numerical models of the ultrasound-tissue interaction, and a stochastic treatment, in order to extract the relevant information and its evolution with sufficient sensitivity. In addition, a stochastic model-class selection formulation is used to rank which one of the proposed interaction models are more plausible. To verify the sensitivity of the system, a gelation process is monitored.
Defect Dynamics in Artificial Colloidal Ice: Real-Time Observation, Manipulation, and Logic Gate (2016)

We study the defect dynamics in a colloidal spin ice system realized by filling a square lattice of topographic double well islands with repulsively interacting magnetic colloids. We focus on the contraction of defects in the ground state, and contraction or expansion in a metastable biased state. Combining real-time experiments with simulations, we prove that these defects behave like emergent topological monopoles obeying a Coulomb law with an additional line tension. We further show how to realize a completely resettable "nor" gate, which provides guidelines for fabrication of nanoscale logic devices based on the motion of topological magnetic monopoles.
RELATIONSHIP BETWEEN EMOTIONAL INTELLIGENCE, PSYCHOLOGICAL STATUS AND MEAN AMBULATORY BLOOD PRESSURE LEVEL IN PATIENTS WITH ARTERIAL HYPERTENSION: PP.3.126 (2010)

Objective: The aim of our study was to determine relationship between emotional intelligence (EI), psychological status (PS) and mean ambulatory blood pressure monitoring (ABPM) level in patient with arterial hypertension (AH). Design and Methods: We analyzed 307ambulatory blood pressure monitoring (ABPM) data of AH patients (Spacelabs 90207) after the washout period. We defined daytime period as 8.00–22.00 (BPd), nighttime – 0.00–6.00 (BPn), evening – 21.00–23.00 (BPe), morning – 6.00–8.00 (BPm),work period - 11.00–19.00 (BPw), day and night - 24 hours (BP24). After ABPM session patients completed the PS and EI questionnaire (“Minnesota Multiphase Personality Inventory”(MMPI), “EmIn Questionnaire, Lyusin D.). It was analyzed following EmIn scale scores: emotion self-awareness; management of one's own emotions; control of emotional expression; understanding others' emotions; management of others' emotions (MOE). We used Spearman Partial Coefficient for correlation analysis adjusted for age, sex and duration of AH. Results: The mean daytime systolic BP (SBP) was 140.1 ± 14.5; diastolic (DBP) - 88.1 ± 9.9 mm Hg (M ± SD). We found negative correlations between (p > 0.05): 1) 2, 7 scale scores and mean systolic BPd, BPn, BPe, BPm, BPw; 2) 7 scale scores and diastolic BPd, BPw scores 3) 3,4 scale scours and SBPe. IEME scale scores were positively correlated (p > 0.05) with SBPd, SBPw level and also with SBPd, SBP24, DBPd load. Thus, asthenia behavioral type related with social conform, compassion, leadership traits absence e. t. c. (2, 7 scale) had negative association with BP level. Behavioral and emotional impulsivity (3, 4 scale) outside of working place (evening time) also had negative correlation with BP. In contrast, higher management of others' emotions (MOE scale) was related with lower SBP level and SBP, DBP load. Conclusions: Higher social adaptation combined with behavioural and emotional relaxation after work was associated with lower BP level. In contrast, higher behavioral interpersonal management related with lower SBP level.
Introduction to the Symposium-in-print: Photoisomerization Pathways, Torsional Relaxation and the Hula Twist¶ (2002)

A review of recent literature on volume-conserving cis-trans photoisomerization reaction mechanism, including hula twist, is presented. Differences between substrates trapped in amorphous solids and chromophores that are protein bound are discussed.
Simulation of interfacial two-step consecutive reactions by diffusion in the mass-transfer kinetics of liquid-liquid extraction of metal cations (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSimulation of interfacial two-step consecutive reactions by diffusion in the mass-transfer kinetics of liquid-liquid extraction of metal cationsP. R. Danesi, G. F. Vandegrift, E. P. Horwitz, and R. ChiariziaCite this: J. Phys. Chem. 1980, 84, 26, 3582–3587Publication Date (Print):December 1, 1980Publication History Published online1 May 2002Published inissue 1 December 1980https://pubs.acs.org/doi/10.1021/j100463a017https://doi.org/10.1021/j100463a017research-articleACS PublicationsRequest reuse permissionsArticle Views298Altmetric-Citations36LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Algorithm performance in the determination of the refractive-index profile of optical fibers (2008)

Three algorithms for computing the refractive-index profile of azimuthally symmetric optical fibers via the inverse Abel transform are compared to determine their relative accuracies. Appropriate values of algorithm parameters are also determined. The direct differentiation algorithm, the iterative algorithm, and the Fourier algorithm are used to calculate the refractive-index profile from simulated measurements of the phase shift of light transmitted transversely through the fiber. The rms error in the calculated index profile is used to quantify the accuracy of each algorithm. The Fourier algorithm is typically the most accurate of the three.
Wisdom of the ages (2010)

Though children frequently use web search engines to learn, interact, and be entertained, modern web search engines are poorly suited to children's needs, requiring relatively complex querying and filtering of results in order to find pages oriented to young audiences. To address this limitation, we designed AgeRank, a link-based algorithm that ranks web pages according their appropriateness for young audiences. We show its effectiveness through a multipart evaluation that demonstrates AgeRank to be accurate in page-labeling, widely-spanning in page coverage, and with high potential to improve children's search. As a fast, scalable, and effective algorithm, AgeRank can be adopted by search engines seeking to more effectively address the needs of young users, or easily fitted to complementary machine-learning based classification approaches.
Traveling from the hypothalamus to the adipose tissue: The thermogenic pathway (2017)

Brown adipose tissue (BAT) is a specialized tissue critical for non-shivering thermogenesis producing heat through mitochondrial uncoupling; whereas white adipose tissue (WAT) is responsible of energy storage in the form of triglycerides. Another type of fat has been described, the beige adipose tissue; this tissue emerges in existing WAT depots but with thermogenic ability, a phenomenon known as browning. Several peripheral signals relaying information about energy status act in the brain, particularly the hypothalamus, to regulate thermogenesis in BAT and browning of WAT. Different hypothalamic areas have the capacity to regulate the thermogenic process in brown and beige adipocytes through the sympathetic nervous system (SNS). This review discusses important concepts and discoveries about the central control of thermogenesis as a trip that starts in the hypothalamus, and taking the sympathetic roads to reach brown and beige fat to modulate thermogenic functions.
Thromboresistant Chemical Sensors Using Combined Nitric Oxide Release/Ion Sensing Polymeric Films (1997)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTThromboresistant Chemical Sensors Using Combined Nitric Oxide Release/Ion Sensing Polymeric FilmsCecilia Espadas-Torre, Vanessa Oklejas, Kelly Mowery, and Mark E. MeyerhoffView Author Information Department of Chemistry, University of Michigan Ann Arbor, Michigan 48109 Cite this: J. Am. Chem. Soc. 1997, 119, 9, 2321–2322Publication Date (Web):March 5, 1997Publication History Received30 August 1996Published online5 March 1997Published inissue 1 March 1997https://pubs.acs.org/doi/10.1021/ja963054ahttps://doi.org/10.1021/ja963054arapid-communicationACS PublicationsCopyright © 1997 American Chemical SocietyRequest reuse permissionsArticle Views457Altmetric-Citations63LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Cells,Ions,Membranes,Polymer films,Sensors Get e-Alerts
Design and theoretical performance analysis of a hybrid time-hopping/TDMA multiple-access indoor wireless communication system (2002)

A multiple-access (MA) scheme for indoor wireless communications is suggested. The proposed MA scheme takes advantage of time-hopping (TH) within multiple frames of a time-division multiple-access (TDMA) system to provide access to the channel for network subscribers. The assignment codes are those of the {0,1} family codes, previously exploited for fiber-optic code-division multiple-access (FO-CDMA) applications. Upper bounds on the overall symbol error rates for differential phase-shift-keying (DPSK) and frequency-shift-keying (FSK) systems are derived when slow, frequency non-selective Rician fading is present.
Multifunctional Nanoprobes for Cancer Cell Targeting, Imaging and Anticancer Drug Delivery (2015)

The diagnosis and treatment of cancer have been greatly improved with recent developments in bio-nanotechnology, including engineering of multifunctional probes. One of the promising nanoscale tools for cancer imaging is fluorescent quantum dots (QDs), whose small size and unique optical properties allow them to penetrate into cells and ensure highly sensitive optical diagnosis of cancer at the cellular level. Furthermore, novel multi-functional probes have been developed in which QDs are conjugated with one or several functional molecules, including targeting moieties and therapeutic agents. Here, the strategy for engineering novel nanocarriers for controlled nucleus-targeted antitumor drug delivery and real-time imaging by single- or two-photon microscopy is described. A triple multifunctional nanoprobe is being developed that consists of a nitrogen-based heterocyclic derivative, an anticancer agent interacting with a DNA in living cells; a recognized molecule serving as a vector responsible for targeted delivery of the probe into cancer cells; and photoluminescent QDs providing the imaging capability of the probe. Subsequent optimization of the multifunctional nanoprobe will offer new possibilities for cancer diagnosis and treatment.