gebhart/patrepeval huggingface dataset:
Perioperative risk assessment of patients using the ‘MyRISK’ digital score completed before the preanesthetic consultation: a prospective, observational trial. (Preprint) (2022)

<sec> <title>BACKGROUND</title> The pandemic highlighted the potential of digital health solutions to adapt the organization of care in a crisis context. </sec> <sec> <title>OBJECTIVE</title> Our aim was to demonstrate the prognostic value of the perioperative ‘MyRISK score’ derived from data collected on a digital conversational agent (chatbot) before the preanesthetic consultation (PAC). </sec> <sec> <title>METHODS</title> Single-center, prospective, observational study. The 16 items composing the MyRISK score were selected by Delphi method. An algorithm was used to stratify low (‘green’), intermediate (‘orange’) and high (‘red’) risk patients. Postoperative complications occurring in the first 6 months (composite criterion) were numerically collected and verified by phone and consultation of the electronic medical database. A logistic regression was carried out to identify their explanatory variables. A machine learning model was trained to predict the MyRISK score using a dataset of 1823 ‘green’ and ‘red’ patients to re-classify ‘orange’ individuals. User satisfaction and usability were assessed. </sec> <sec> <title>RESULTS</title> Four hundered and one patients were included. Sixteen of the 389 patients (4.1%) analyzed for the primary endpoint experienced a postoperative complication. An ASA score ≥ 3 and a ‘red’ score were independent predictors of postoperative complications (Odds Ratios of 5.8 [CI95%: 1.7 - 20.2; p=0.006] and 5.9 [CI95%: 1.5 - 22.3; p=0.009] respectively). Once ‘orange’ patients re-classified according to the prediction of the trained model, a ‘red’ score was identified as a strong predictor of postoperative complications with an Odds Ratio of 21.8 [CI95%: 2.8 - 171.5; p=0.003]. Patient satisfaction Numeric Rating Scale and System Usability Scale were 8 [7-9]/10 and 90 [82.5-95]/100 respectively. </sec> <sec> <title>CONCLUSIONS</title> We demonstrate the good prognostic predictive value of the MyRISK digital perioperative risk score established before the PAC. Its predictive strength was increase using a machine learning model reclassifying intermediate-risk patient. This numerical categorization could be used to guide patients between teleconsultation and face-to-face PAC, or to provide a perioperative personalized care pathway for high-risk patients. </sec>
Failure-Atomic Slotted Paging for Persistent Memory (2017)

The slotted-page structure is a database page format commonly used for managing variable-length records. In this work, we develop a novel "failure-atomic slotted page structure" for persistent memory that leverages byte addressability and durability of persistent memory to minimize redundant write operations used to maintain consistency in traditional database systems. Failure-atomic slotted paging consists of two key elements: (i) in-place commit per page using hardware transactional memory and (ii) slot header logging that logs the commit mark of each page. The proposed scheme is implemented in SQLite and compared against NVWAL, the current state-of-the-art scheme. Our performance study shows that our failure-atomic slotted paging shows optimal performance for database transactions that insert a single record. For transactions that touch more than one database page, our proposed slot-header logging scheme minimizes the logging overhead by avoiding duplicating pages and logging only the metadata of the dirty pages. Overall, we find that our failure-atomic slotted-page management scheme reduces database logging overhead to 1/6 and improves query response time by up to 33% compared to NVWAL.
A Rapid, Reliable and Less-destructive On-chip Mass Measurement for 3D Composite Material Testing Microstructures (2020)

Mass measurements of complex three-dimensional microstructures are essential to the design and development of microsystems. However, the mass measurements of such microstructures require several manipulation steps which are not well controlled. We have demonstrated a rapid, reliable and less-destructive on-chip mass measurement method by incorporating with AFM micromanipulation. It is based on AFM pick-measure-place micromanipulation using Van der Waals attraction and the mass measurement by resonant frequency shift. The measurement sensitivity revealed to be 25 Hz/pg and it could be promising to characterize MEMS with complex geometries and composite materials.
Breathing building: A decentralized façade-integrated solar air-conditioning system (2014)

A decentralized adaptive solar air conditioning system is presented, which contains usual air-conditioning equipment and a new module, designed with a honeycomb structure, containing phase change material for latent thermal cold and hot energy storage. Heat recovery devices are responsible for higher system efficiency. A low-cost configuration and a multi-function deluxe version are presented,where in the second case a (magnetic) heat pump, a (magnetic) cooling device and an evaporative apparatus are added. Whereas the simple configuration is of medium cost and shows a good energy saving potential, the deluxe version is more expensive, but, on the other hand, is designed to show a higher energy saving potential. It is also expected to yield exquisite indoor hygienic and climatic conditions.
Laparoscopic Exposure of the Pancreas and Staging of Pancreatic Cancer (1996)

Laparoscopy combined with laparoscopic contact ultrasonography was recently proposed as a new and effective method for staging and assessment of resectability in pancreatic cancer. In order to limit the occurrence of false-negative findings, the laparoscopic technique should be as close as possible to the equivalent laparotomic procedure. That includes opening of the lesser sac, which is best achieved through an infragastric route, with resulting wide exposure of the pancreatic body and tail. Laparoscopic contact ultrasonography is then performed for the purpose to define tumor limits, study relationships with major vessels, and assess limphnodal invasion. The results of this procedure in a series of 25 patients are discussed in this report. It is concluded that laparoscopic staging of pancreatic cancer is safe and effective in achieving the goal of avoiding unnecessary laparotomies and selecting candidates for surgical resection.
Economic Feasibility of Cooling Dry Cows: Findings and Spreadsheet (2018)

The negative effects of heat stress in lactating cows are well known, but only recent studies have explored those effects along with the full benefits of cooling dry cows. Recent work at the University of Florida has demonstrated the benefits of dry cow cooling on calf performance and cow health in the next lactation. This 5-page fact sheet discusses the economic losses from milk production due to heat stress, investment, utilities, maintenance, and feasibility analysis. Written by Fernanda Ferreira, Geoffrey Dahl, and Albert De Vries, and published by the UF/IFAS Department of Animal Sciences, March 2018. http://edis.ifas.ufl.edu/an342
RFLP relationships of A-genome species in the genus Oryza (2000)

RFLPs of 192 accessiens ef A-genome rice species were aRalyzed ORe plant vvas used to represent each accession assayed RFLPs were detected for the combinations of Dra 1-digested total DNA and tweRty-one sirgle-copy genomic cones A dendrogram was constructed using ePGAryiethd frrl a geRetic distaxceaxasscafhe A-geRmece speces based on RFLP analysis matched well with the conventional classcation The African annual species O gtaberrimct and O barthii were not clearly differentiated by RFLP loci while the Assecies a 3v O)ogen and Ozivara f)ed a cex wheee ofe species can easily be distinguished from each other An Asian sub-group that is clearly differentiated from other Asian A-genome germplasm was identified This consists of some O gon accessions that dd nt cster withe cutivaed rce buomed 1sely k groups Some accessions of O(were closely aned to(ca rice cultivars whe the others mainly from China were closely aligned with Japonica cultivars Most of O accessions from Latin America foed a group which was more closely reled to O glaberriza aRd O barShii thak other species Two accessieRs gf O ggecmaepatecga however were aligned with lndica cultivars of Asia lt is possible that the A-genome wild rices in Latin America are of two types O rufipogoz from the Sepik river of Papua New Guinea was eaterta1whhad RFLPgesRy
Ionic liquid crystal elastomers-based flexible organic electrochemical transistors: Effect of director alignment of the solid electrolyte (2022)

Organic electrochemical transistors (OECTs) have attracted great attention since their discovery in 1984 due to their flexibility and biocompatibility. Although an intense focus has been put on the design of new organic semiconductors, fewer efforts are directed toward the development of optimized electrolytes. However, the electrolyte is an integral part of OECTs and strongly influences the transient responses of these devices. Also, best performing OECTs currently use liquid electrolytes, but there is a growing need for solid electrolytes, as they can be easily integrated into wearable devices. In this paper, we demonstrate that ionic liquid crystal elastomers (iLCEs) can be used as solid electrolytes of flexible, substrate-free organic electrochemical transistors. We introduce the alignment of the director of the liquid crystal elastomers as a new parameter to tune and improve both steady state and transient responses. The normalized maximum transconductance gm/w of the most sensitive iLCE was found to be the highest (7 Sm−1) among all solid state-based OECTs.
A novel short‐lived emission from the photosynthetic bacterium Rhodospirilum rubrum (1976)

When growing a mutant strain of Rhodospirillum rubrum (carotenoid-less mutant blue-green strain G-9) it was observed that the culture emits red light strong enough to be seen even directly in day light.The emission was also observed from dilute suspensions of chromatophores.Examination with a fluorimeter revealed that both the wild type and the mutant exhibited emission; however, the mutant's emission was about six times greater.This emission appeared in addition to the ordinary infrared emission of bacteriochlorophyl, and could not be attributed to bacteriochlorophyl due to the considerable mismatch between its wavelength and the absorption of bacteriochlorophyll, which occurs at much longer wavelengths.A search into the literature did not reveal any observations of such fluorescence, except for a single report [1 ] on weak delayed light (in the msec time range) of similar spectrum, from chromatophores of RhodospMllum rubrum and Rhodopseudomonas spheroides.This delayed light was only detectable under anaerobic conditions.Surprisingly, no mention was made in this report [1] of in vivo prompt fluorescence, although the authors reported that similar fluorescence is emitted by an isolated compound (according to them Mg-Protoporphyrin IX) in vitro.In this communication we wish to establish and characterize the red fluorescence from R. rubrum.
Latency Assurances for Multi-Class Traffic at the QoS-Capable Home Network Wireless Access Point (Tutorial) (2011)

Emerging broadband networks and technologies have changed the way of home network provision. Provisioning the broadband services has merely accelerated the complexity of home networks to grow. The services demanded by applications are still inadequate under current home network infrastructures. These services require different Quality of Service (QoS) requirements from the networks. As wireless-based communication within the home (e.g. 802.11´) gains wide acceptance because of its mature protocol, becoming the predominant technology for home networking, the question of efficient QoS-aware wireless access point resource allocation and scheduling function implementation arises. In this article we present a resource management and scheduling algorithm for a QoS-aware wireless access point for use in enterprise and home network solutions. The presented algorithm provides delay and packet loss service guarantees to a diverse set of application traffic classes, produced as a result of convergence of home entertainment and data networks. The algorithm is simple, controllable, and scalable for implementation with the support of both absolute and relative QoS guarantees to multi-class traffic.
Molecular Cloning and Expression of Rat Liver Endo-α-mannosidase, an N-Linked Oligosaccharide Processing Enzyme (1997)

A clone containing the open reading frame of endo-alpha-D-mannosidase, an enzyme involved in early N-linked oligosaccharide processing, has been isolated from a rat liver lambdagt11 cDNA library. This was accomplished by a strategy that involved purification of the endomannosidase from rat liver Golgi by ligand affinity chromatography (Hiraizumi, S., Spohr, U., and Spiro, R. G. (1994) J. Biol. Chem. 269, 4697-4700) and preparative electrophoresis, followed by sequence determinations of tryptic peptides. Using degenerate primers based on these sequences, the polymerase chain reaction with rat liver cDNA as a template yielded a 470-base pair product suitable for library screening as well as Northern blot hybridization. EcoRI digestion of the purified lambda DNA released a 5.4-kilobase fragment that was amplified in Bluescript II SK(-) vector. Sequence analysis indicated that the deduced open reading frame of the endomannosidase extended from nucleotides 89 to 1441, encoding a protein of 451 amino acids and corresponding to a molecular mass of 52 kDa. Data base searches revealed no homology with any other known protein. When a vector coding for this protein fused to an NH2-terminal peptide containing a polyhistidine region was introduced into Escherichia coli, high levels of the enzyme were expressed upon induction with isopropyl-beta-D-thiogalactoside. Purification of the endomannosidase to electrophoretic homogeneity from E. coli lysates was accomplished by Ni2+-chelate and Glcalpha1-->3Man-O-(CH2)8CONH-Affi-Gel ligand chromatographies. Polyclonal antibodies raised against this protein reacted with Golgi endomannosidase. By both immunoblotting and silver staining, the purified E. coli-expressed enzyme was approximately 8 kDa smaller than anticipated from the open reading frame; timed induction studies indicated that this was due to scission of the enzyme's COOH-terminal end by host cell proteases. All rat tissues examined demonstrated mRNA levels (4.9-kilobase message) for the endomannosidase that correlated well with their enzyme activity.
Photo Quiz: A 22-Year-Old Yemeni Woman with Recurrent Right Upper Quadrant Abdominal Pain (2012)

A 22-year-old female presented to the emergency department of the Alameda County Medical Center, complaining of right upper quadrant (RUQ) cramping abdominal pain that had been present for the past 10 days. Her pain was worse with palpation and walking and was not associated with food intake. Her
B to Z transitions in DNA and their biological implications (1986)

A review with 152 refs. with emphasis on the mechanism and regulation (including exogenous effectors) of the transition
Medicinal attributes of Solanum xanthocarpum fruit consumed by several tribal communities as food: an in vitro antioxidant, anticancer and anti HIV perspective (2014)

The study demonstrated considerable antioxidant and anticancer activities in S. xanthocarpum fruit.
Apoptosis and Necrosis in Cerebrovascular Disease (1999)

Neuronal death following ischemic insults has been thought to reflect necrosis. However, recent evidence from several labs suggests that programmed cell death, leading to apoptosis, might additionally contribute to this death. We have used both in vitro and in vivo models to study the role of apoptosis in ischemic cell death. Some features of apoptosis (TUNEL staining, internucleosomal DNA fragmentation, sensitivity to cycloheximide) were observed following transient focal ischemia in rats. Brief transient focal ischemia was followed by delayed infarction more than 3 days later; this delayed infarction was sensitive to cycloheximide. A cycloheximide-sensitive component of neuronal cell death was also observed in cultured murine neocortical neurons deprived of oxygen-glucose in the presence of glutamate receptor antagonists. This presumed ischemic apoptosis was attenuated by caspase inhibitors, or by homozygous deletion of the bax gene. Neurons may undergo both apoptosis and necrosis after ischemic insults, and thus it may be therapeutically desirable to block both processes.
Fourier Transform Infrared Spectra of Drying Oils Treated by Irradiation (2008)

Drying oils, such as linseed oil and tung oil, have the potential as coating materials to improve barrier properties of biobased packaging films. Oil drying is a chemical reaction in which polyunsaturated fatty acids undergo autoxidation. During drying, oils polymerize and form water-resistant films. However, drying rates tend to be too slow for practical applications. Metal driers are used in the paint industry to accelerate drying, but often driers are not safe for food contact. The objective of this work was to investigate the effect of ionizing radiation on the oxidation or drying rate of drying oils. The effect of irradiation dose on the drying rate of linseed and tung oils was monitored by FTIR spectroscopy. The peak at 3010 cm (-1) was found to be a useful index of oxidation rate. The decrease in peak intensity with time was fitted with exponential functions of the form Abs = Abs 0 exp (- t/ k), where Abs 0 is the initial absorbance and 1/ k is the rate constant for the oxidation process. Values for k were 9.91 ( R (2) = 0.98), 6.59 ( R (2) = 0.95)n and 6.44 ( R (2) = 0.97) for radiation levels of 0, 50, and 100 kGy, respectively. The k values suggested that the oxidation rate increased as the radiation dose increased from 0 to 50 kGy. A further increase to 100 kGy had only a limited effect.
Isolation and characterization of two new peptides, mastoparan C and crabrolin, from the venom of the European hornet, Vespa crabro. (1984)

Two peptides rich in hydrophobic amino acids have been isolated from venom sacs of the European hornet, Vespa crabro. One peptide (P-2) is structurally and functionally related to the tetradecapeptide mastoparan and has been named mastoparan C. Leu-Asn-Leu-Lys-Ala-Leu-Leu-Ala-Val-Ala-Lys-Lys-Ile-LeuNH2. The other (P-1) is a tridecapeptide with a new sequence: Phe-Leu-Pro-Leu-Ile-Leu-Arg-Lys-Ile-Val-Thr-Ala-LeuNH2 which we have named crabrolin. The peptide releases histamine from rat peritoneal mast cells with a threshold of approximately 2.5 micrograms/ml (congruent to 8 microM). Crabrolin also facilitates the action of purified phospholipase A2 from different sources, but it is not quite as active as mastoparan. It is clearly less active than mastoparan in lysing erythrocytes, and it does not release amylase from dispersed guinea pig pancreatic acini. Given its unique sequence, the principal effect of crabrolin may be neither mast cell degranulation nor phospholipase facilitation, but a yet undiscovered action.
Influence of apparatus geometry and deposition conditions on the structure and topography of thick sputtered coatings (1974)

Two cylindrically symmetric and complementary sputtering geometries, the post and hollow cathodes, were used to deposit thick (∼25-μ) coatings of various metals (Mo, Cr, Ti, Fe, Cu, and Al-alloy) onto glass and metallic substrates at deposition rates of 1000–2000 Å/min under various conditions of substrate temperature, argon pressure, and plasma bombardment. Coating surface topographies and fracture cross sections were examined by scanning electron microscopy. Polished cross sections were examined metallographically. Crystallographic orientations were determined by x-ray diffraction. Microstructures were generally consistent with the three-zone model proposed by Movchan and Demchishin [Fiz. Metal. Metalloved. 28, 653 (1969)]. Three differences were noted: (1) at low argon pressures a broad zone 1–zone 2 transition zone consisting of densely packed fibrous grains was identified; (2) zone 2 columnar grains tended to be faceted at elevated temperatures, although facets were often replaced by smooth flat surfaces at higher temperatures; (3) zone 3 equiaxed grains were generally not observed at the deposition conditions investigated. Hollow cathode deposition accentuated those features of coating growth that relate to intergrain shading.
CpG Therapy is Superior to BCG in an Orthotopic Bladder Cancer Model and Generates CD4+ T-cell Immunity (2008)

Bacillus Calmette Guérin (BCG) immunotherapy has been successful in extending tumor remission in bladder cancer, the fifth most common cancer in men. However, relapses are frequent and some patients develop resistance to BCG. CpGs were previously demonstrated to be effective in the murine MB49 model. In this paper, we modeled a more aggressive orthotopic bladder cancer than previously studied. Moreover, we compared standard BCG immunotherapy side-by-side with the Toll-like receptor-9 agonist CpG. MB49 tumor-bearing mice were treated with BCG or CpG and survival as well as tumor progression were observed over time. Urine, blood, and tumors were collected and analyzed. Mice were rechallenged and evaluated for tumor-specific immunity. In this study, CpGs induced a complete response of large aggressive orthotopic MB49 bladder tumors, resulting in tumor-specific systemic immunity. Further, data indicated that this potent antitumor effect required T cells. A comparison of CpGs and BCG in both a highly and less aggressive orthotopic tumor model, and in a subcutaneous tumor model, demonstrated that CpGs were superior to BCG. In the orthotopic model, BCG induced a local cytokine storm during treatment initiation whereas CpG affected a more refined cytokine pattern over time. Increased levels of cytokines in serum correlated with enhanced survival in the subcutaneous model. Further, immune cell depletion studies demonstrated that CpG-induced protective immunity was CD4+ T-cell dependent. Taken together, our data suggest that CpGs are superior to BCG for bladder cancer immunotherapy. Thus, this potent new drug may be an attractive therapeutic alternative and should be evaluated in bladder cancer patients.
Lattice-matched magnetic tunnel junctions using a Heusler alloy Co2FeAl and a cation-disorder spinel Mg-Al-O barrier (2014)

Perfectly lattice-matched magnetic tunnel junctions (MTJs) consisting of a Heusler alloy B2-Co2FeAl (CFA) electrode and a cation-disorder spinel (Mg-Al-O) barrier were fabricated by sputtering and plasma oxidation. We achieved a large tunnel magnetoresistance (TMR) ratio of 228% at room temperature (RT) (398% at 5 K) for the epitaxial CFA/MgAl-O/CoFe(001) MTJ, in which the effect of lattice defects on TMR ratios is excluded. With inserting a ultrathin (≤1.5 nm) CoFe layer between the CFA and Mg-Al-O, the TMR ratio further increased up to 280% at RT (453% at 5 K), which reflected the importance of controlling barrier-electrode interface states other than the lattice matching.