gebhart/patrepeval huggingface dataset:
Cyanide-Bridged Fe(III)−Mn(III) Bimetallic Systems Assembled from the fac-Fe Tricyanide and Mn Schiff bases: Structures, Magnetic Properties, and Density Functional Theory Calculations (2010)

Reaction of [(Tp)Fe(CN)(3)](-) [Tp = hydrotris(pyrazolyl)borate] with respective Mn(III) Schiff bases led to the formation of four dimeric molecules, [(Tp)Fe(CN)(3)][Mn(1-napen)(H(2)O)].MeCN.4H(2)O [1; 1-napen = N,N'-ethylenebis(2-hydroxy-1-naphthylideneiminato) dianion], [(Tp)Fe(CN)(3)][Mn(5-Clsalen)(H(2)O)] [2; 5-Clsalcy = N,N'-(trans-1,2-cyclohexanediylethylene)bis(5-chlorosalicylideneiminato) dianion], [(Tp)Fe(CN)(3)][Mn(2-acnapen)(MeOH)].MeOH [3; 2-acnapen = N,N'-ethylenebis(1-hydroxy-2-acetonaphthylideneiminato) dianion], [(Tp)Fe(CN)(3)][Mn(3-MeOsalen)(H(2)O)] [4; 3-MeOsalen = N,N'-ethylenebis(3-methoxysalicylideneiminato) dianion], and a one-dimensional (1D) zigzag chain [(Tp)Fe(CN)(3)][Mn(2-acnapen)].H(2)O (5). The dimers contain multiple intermolecular interactions such as hydrogen bonds, face-to-face pi-pi contacts, and edge-to-face CH-pi forces, raising molecular dimensions from one-dimensional (1D) up to three-dimensional (3D) arrays, whereas there are no pi-pi stacking interactions in the 1D chain compound. Magnetic measurements reveal that ferromagnetic couplings are obviously operative between Mn(III) and Fe(III) spin centers transmitted by CN bridges for 1-3 and 5, and antiferromagnetic interactions are however unexpectedly present in 4. On the basis of the proper spin Hamiltonians, magnetic exchange couplings are estimated to be in the span from 1.79 to 7.48 cm(-1) for the ferromagnetically coupled systems and -1.40 cm (-1) for the antiferromagnetic dimer. A slow magnetic relaxation is tangible in 5, which is in connection with isolated chains devoid of any intermolecular noncovalent interactions. Density Functional Theory (DFT) calculations and comparison of structural parameters suggest that the observed magnetic behaviors are mainly associated with the bending of the Mn-N[triple bond]C angle in the bridging pathway.
Modeling and Simulation for Control of the TEALARC Liquified Natural Gas Process (2010)

This article describes a dynamic, control relevant, mechanistic model of the TEALARC liquified natural gas process. The model is to be used for both steady-state and dynamic controllability analysis. The model therefore needs to be computationally light, but still include enough complexity such as to study the impact of capacity constraints on the control structure. Structured assumptions have been used to obtain simplified representations of gas/liquid flows and thermodynamic properties. The steady-state operating points of the dynamic model have been adapted to a given steady-state process design model. The paper demonstrates that the model is well suited for operability analysis. Steady-state and dynamic characteristics are illustrated.
A Framework for Robust Audio Fingerprinting (2010)

We present a framework for audio fingerprint-&#13;\ning, rather general in its essence, but especially tuned for&#13;\nbeing used in the context of broadcast monitoring. We&#13;\nefficiently implemented a robust fingerprinting algorithm&#13;\nand a suitable retrieval method. Ample sections are devoted&#13;\nto strategies for improving both the reliability and the speed&#13;\nof the overall system. The outcomes of plentiful experiments&#13;\non a database of 100 000 songs are analyzed, and two&#13;\ncommon kinds of distortion (pitching and thermal noise)&#13;\nare investigated. To better drive design decisions, we also&#13;\nprovide in-depth discussion on the scalability of the indexing&#13;\nalgorithm.
ChemInform Abstract: Bis‐Heterocycles as Potential Chemotherapeutic Agents. Part 10. Synthesis of Bis(4‐arylthiosemicarbazido)‐, Bis(2‐arylamino‐1,3,4‐thiadiazol‐5‐yl)‐ and Bis(4‐aryl‐1,2,4‐triazolin‐3‐thione‐5‐yl)pentanes and Related Compounds. (1990)

Abstract The title compounds of type (III)‐(V), (VII) and (VIII) are screened for antifungal activity.
Temporal transcriptomic analysis of the Listeria monocytogenes EGD-e σB regulon (2008)

Genes comprising the sigmaB regulon encode solute transporters, novel cell-wall proteins, universal stress proteins, transcriptional regulators and include those involved in osmoregulation, carbon metabolism, ribosome- and envelope-function, as well as virulence and niche-specific survival genes such as those involved in bile resistance and exclusion. Ten of the sigmaB-positively regulated genes of L. monocytogenes are absent in L. innocua. A total of 75 sigmaB-positively regulated listerial genes had homologs in B. subtilis, but only 33 have been previously described as being sigmaB-regulated in B. subtilis even though both species share a highly conserved sigmaB-dependent consensus sequence. A low overlap of genes may reflects adaptation of these bacteria to their respective environmental conditions.
Anion-induced stabilization of human serum albumin prevents the formation of intermediate during urea denaturation (2000)

The unfolding of human serum albumin (HSA), a multidomain protein, by urea was followed by far-UV circular dichroism (CD), intrinsic fluorescence, and ANS fluorescence measurements. The urea-induced transition, which otherwise was a two-step process with a stable intermediate at around 4.8 M urea concentration as monitored by far-UV CD and intrinsic fluorescence, underwent a single-step cooperative transition in the presence of 1.0 M KCl. The free energy of stabilization (DeltaDelta G(H2O)D) in the presence of 1 M KCl was found to be 1,090 and 1,200 cal/mol as determined by CD and fluorescence, respectively. The salt stabilization occurred in the first transition (0-5.0 M urea), which corresponded to the formation of intermediate (I) state from the native (N) state, whereas the second transition, corresponding to the unfolding of I state to denatured (D) state, remained unaffected. Urea denaturation of HSA as monitored by tryptophan fluorescence of the lone tryptophan residue (Trp(214)) residing in domain II of the protein, followed a single-step transition suggesting that domain(s) I and/or III is (are) involved in the intermediate formation. This was also confirmed by the acrylamide quenching of tryptophan fluorescence at 5 M urea, which exhibited little change in the value of Stern-Volmer constant. ANS fluorescence data also showed single-step transition reflecting the absence of accumulation of hydrophobic patches. The stabilizing potential of various salts studied by far-UV CD and intrinsic fluorescence was found to follow the order: NaClO(4) > NaSCN >Na(2)SO(4) >KBr >KCl >KF. A comparison of the effects of various potassium salts revealed that anions were chiefly responsible in stabilizing HSA. The above series was found similar to the electroselectivity series of anions towards the anion-exchange resins and reverse of the Hofmeister series, suggesting that preferential binding of anions to HSA rather than hydration, was primarily responsible for stabilization. Further, single-step transition observed with GdnHCl can be ascribed to its ionic character as the free energy change associated with urea denaturation in the presence of 1.0 M KCl (5,980 cal/mol) was similar to that obtained with GdnHCl (5,870 cal/mol).
pH‐reversible magnetic gel with a biodegradable polymer (2004)

Abstract Polymer gels that react to external stimuli, such as pH, temperature, and electromagnetic fields, are an important class of materials. Such materials have pharmaceutical, industrial, and biomedical applications. Our intention in this study was to synthesize a stimuli‐responsive polymer gel with a biodegradable polymer. However, the chemical crosslinker, divinyl sulfone, which is most widely used for the crosslinking of this type of material, is highly toxic in nature. To overcome this problem, a reversible magnetic gel was synthesized with hydroxy propyl cellulose (HPC) and maghemite at pH 13 without with a chemical crosslinker. With a decrease in pH from 13 to 9, the gel formed a homogeneous dispersion of HPC particles with maghemite in it. This process was a reversible physical gelation where the crosslinks of the network had a physical origin (in this case, hydrogen bonding) and, therefore, were sensitive to variations in pH. When this physically prepared gel was compared with the chemically crosslinked one, no significant differences in structural properties were noted. At higher pH values, the gel was formed due to weak intermolecular hydrogen bonding, as observed by the broadening of the IR band in both the magnetic and nonmagnetic gels. Transmission electron micrographs also showed no significant difference in the gel morphology. Differential scanning calorimetry showed an increase in melting temperature for the gel sample compared to that of pure HPC. © 2004 Wiley Periodicals, Inc. J Appl Polym Sci 91: 3337–3341, 2004
Design of Linear Feedback Controllers for Dynamic Systems With Hysteresis (2013)

This paper proposes an approach to deal with the control of a class of dynamical systems affected by hysteresis, which is particularly common in applications of smart materials to motion control. The controlled plant is assumed to be a combination of a linear system with a hysteretic operator that can appear either in series or in a feedback path with respect to the linear component, while the controller is defined as a linear combination of the tracking error, its integral and derivatives. This paper mainly focuses on tracking behavior with constant references, and formulates the output regulation as a problem of stability of a polytopic linear differential inclusion, which does not require the identification of an accurate (direct or inverse) model of the hysteresis. The resulting conditions allow the user to seek for controller parameters that guarantee the achievement of a predefined control goal by solving a linear matrix inequality problem. Beside validation through numerical simulation, the method is successfully applied to control a challenging and innovative system, which uses two bars of magnetic shape memory alloy as the active elements of a multistable precise positioning device.
Substrate reactions and flux pinning structures in melt-processed YBa{sub 2}Cu{sub 3}O{sub 7} deposits on Ag-Pd alloy substrates (1992)

Results on melt-processing of thick deposits of highly homogeneous, submicron Y-123 powders prepared by aerosol pyrolysis on Ag-Pd alloy substrates are discussed. For long-term treatments at high temperatures, the extent of the substrate/deposit reaction increased with the Pd content of the substrate. At high Pd concentrations a Ba-Cu-Pd-O phase was formed, resulting in phase segregation of the deposit. For low Pd concentrations the only evidence of a reaction was the presence of a low density of copper oxide precipitates in the Ag-Pd substrate. TEM examination indicated that the substrate/deposit boundary was sharp, and no evidence of Pd contamination was found at 123/123 grain boundaries intersecting the substrate. The melt-processed deposits contain a very fine dispersion of 211 particles within the 123 phase. TEM examination has revealed the presence of a high density of stacking faults in the 123 near the 211/123 interfaces. Simple considerations suggest that these defects may be effective flux pinners for fields directed perpendicular to the basal plane.
Diabetes (2018)

Diabetes in relation to dentistry is the topic of this chapter. The incidence of diabetes is increasingly rapidly, hand-in-hand with the increase in obesity. Obesity predisposes patients to an increased insulin resistance, i.e. reduces their ability to increase the glucose transport into adipocytes, muscle, and liver cells. The pancreas responds by producing more insulin but when it can no longer produce enough to overcome the insulin resistance, the blood glucose rises. Diabetes is characterized by raised blood glucose. We describe the devastating long-term effects of diabetes, in particular the microvascular and macrovascular medical complications. The dental complications include an increased severity of periodontal disease, oral candidiasis, and dry mouth but in those who are poorly controlled the impaired defence mechanisms can lead to severe head and neck infections and osteomyelitis. A final summary lists the important clinical recommendations for treatment of diabetic patients.
Stimulated Emission Pumping Enabling Sub-Diffraction-Limited Spatial Resolution in CARS Microscopy (2012)

Suppression of CARS signal generation is demonstrated by equalization of the ground and Raman states via a control state in a theoretical investigation. Using donut-shaped control light fields for population transfer results in sub-diffraction-limited spatial resolution CARS microscopy.
Bioelectrical Impedance Monitoring in the Prevention of Intravasation Syndrome During Operative Hysteroscopy (2006)

Objective: Our purpose was to evaluate the efficacy of the Soft Tissue Analyzer (STA, Akern Srl, Firenza, Italy), an instrument for the continuous and noninvasive monitoring of fluid volumes based on the measurement of bioelectrical impedance, used during operative hysteroscopy, in order to prevent intravasation syndrome. Methods: Among a total of 233 consecutive patients experiencing abnormal uterine bleeding (spotting, menorrhagia or menometrorrhagia), 141 underwent hysteroscopic polipectomy and 92 underwent hysteroscopic myomectomy. Bioelectrical data were taken in the preoperative and intraoperative periods. Biochemical data (natriemia and plasma osmolality) were also measured before and after the operation to assess the efficacy of this tool in monitoring these modifications and possible onset of intravasation syndrome. Results: Bioelectrical impedance showed no significant increase in extracellular water as expression of fluid overload by distension media, and this was confirmed by the normality of biochemical data. No case of intravasation syndrome was diagnosed. Conclusions: This method may be considered a useful and safe instrument for fluid-balance monitoring to prevent intraoperative and postoperative conditions of fluid overload during operative hysteroscopy.
X-Ray crystallographic analysis of 3-(2′-phenyl-2,4′-bithiazole-4-carboxamido)propyldimethylsulphonium iodide, an analogue of the DNA-binding portion of bleomycin A2 (1982)

The crystal and molecular structure of the title compound, an analogue of the DNA binding region of bleomycin A2, has been determined by X-ray crystallography. All the three independent molecules in an asymmetric unit are approximately planar with fully extended side chains. A computer graphics model-building study has shown that the phenyl group and the second thiazole ring can be intercalated between the base pairs of the double-stranded deoxydinucleoside phosphate d(CpG), and also that the sulphonium cation can interact with a backbone phosphate group. This model is in accord with NMR spectral data.
Development and External Validation of Interpretable Partial Dependent Plot-based Triage Score for Emergency Departments (2022)

Abstract Triage in an emergency department (ED) can help identify the urgency of patients’ treatment and allocate the appropriate resources. Interpretable machine learning methods could be a helpful tool for facilitating the triage process. However, existing related research used only conventional logistic regression methods. This study aims to develop and externally validate an interpretable machine learning model using a partial dependent plot (PDP). This retrospective cohort study included all adult ED patients of the Samsung Medical Center for development and Tan Tock Seng Hospital, from 2016–2020. The outcome of interest was in-hospital mortality after patients’ ED visit. We used the area under the receiver operating characteristic curve (AUROC) to assess the performance of the PDP score and other conventional scores, including the Korea Triage Acuity Scale (KTAS). Of the included 285,523 ED visits, 1.60% ended in in-hospital mortality. The PDP score achieved an AUROC of 0.821 in temporal validation and 0.833 in external validation, outperforming the KTAS score of 0.729. The PDP triage score was therefore superior to other scores for in-hospital mortality prediction. PDP is a generic, intuitive, and effective triage tool to stratify general patients who present to the ED.
Does aging differentially reduce heart rate variability related to respiration? (1984)

Segments of resting heart rate were submitted to spectral analysis in order to assess changes in spectral power with age. Different frequencies of heart rate variability have been related to vagal and sympathetic cardiac control. Data were from 56 male volunteers ranging in age between 18 and 65 years of age. Spectral results revealed that respiratory sinus arrhythmia declined less with age than lower (vasomotor) frequencies. Assessment of total (rather than relative) power at respiratory frequencies revealed the expected drop in power with age. Thus, the decline in heart rate variability with age may not be due predominantly to a decline in frequencies related to respiration.
Analyzing and controlling accuracy in stochastic circuits (2014)

Stochastic computing (SC) is an approximate computing technique that represents data by probabilistic bit-streams called stochastic numbers (SNs). Arithmetic operations can be implemented at very low cost by means of SC. To achieve acceptable accuracy, interacting SNs must usually be statistically independent or uncorrelated. Correlation is poorly understood, however, and is a key problem in SC because of its impact on accuracy and the high cost of correlation-reducing logic. In this paper we analyze and quantify the role of correlation in stochastic circuit design. We use an algebraic framework based on probabilistic transfer matrices (PTMs) to analyze correlation-induced errors. We compare two systematic correlation-reducing methods, regeneration and isolation. Regeneration introduces new (pseudo) random sources to re-randomize SNs, while isolation uses delays (D flip-flops) to derive multiple independent SNs from a single random source. We present bounds on accuracy loss due to isolator insertion and compare its hardware cost to that of regeneration. We conclude that the isolation method can offer significant cost advantages in reducing correlation errors.
Reaction time as an indicator of stimulus‐response binding in affective judgment of visual stimuli1 (2012)

Abstract Conventional studies on affective meanings have been conducted using the semantic differential technique. Although it offers reasonably valid and reliable measures for the bindings between visual stimuli and affective responses, it is dependent on subjective rating. Thus, the present study examined whether the reaction time (RT) of affective judgments for visual stimuli (color, shape, and facial expression) can be an objective indicator of the strength of stimuli‐response bindings. The results can be summarized as follows: (a) RTs for judging Evaluation were longer regardless of stimulus type; (b) RTs for Activity were shorter regardless of stimulus type; and (c) RTs for Lightness and Sharpness depended on stimulus type. These phenomena are consistent with the findings of previous affective meaning studies, suggesting that the RTs for affective judgments can be useful indicators reflecting the strength of the bindings between stimulus properties and affective meanings across various target stimuli and rating scales.
Reduced Glutathione Enhances Fertility of Frozen/Thawed C57BL/6 Mouse Sperm after Exposure to Methyl-Beta-Cyclodextrin Short title: Glutathione facilitates fertilization in mice Summary sentence: Adding reduced glutathione to in vitro fertilization medium modifies the oocyte zona pellucida and enhances the fertilization rate using frozen/thawed C57BL/6 mouse sperm. (2011)

Sperm cryopreservation is useful for the effective storage of genomic resources derived from genetically engineered mice. However, freezing the sperm of C57BL/6 mice, which is the most commonly used genetic background for genetically engineered mice, considerably reduces its fertility. We previously reported that methyl-beta-cyclodextrin dramatically improved the fertility of frozen/thawed C57BL/6 mouse sperm. Recently it was reported that exposing sperm to reduced glutathione may alleviate oxidative stress in frozen/thawed mouse sperm, thereby enhancing in vitro fertilization (IVF); however, the mechanism underlying this effect is poorly understood. In this study, we examined the combined effects of methyl-beta-cyclodextrin and reduced glutathione on the fertilization rate of IVF with frozen/thawed C57BL/6 mouse sperm and the characteristic changes in the zona pellucida by induced by reduced glutathione. Results showed that adding reduced glutathione to the fertilization medium increased the fertilization rate. We found that methyl-beta-cyclodextrin and reduced glutathione independently increased fertilization rates, and their combination produced the strongest effect. We found that reduced glutathione increased the amount of free thiols in the zona pellucida and promoted zona pellucida enlargement. Finally, two-cell embryos produced by IVF with the addition of reduced glutathione developed normally and produced live offspring. In summary, we have established a novel IVF method using methyl-beta-cyclodextrin during sperm preincubation and reduced glutathione during the IVF procedure to enhance fertility of frozen/thawed C57BL/6 mouse
Versatile mobile lidar system for environmental monitoring (2003)

A mobile lidar (light detection and ranging) system for environmental monitoring is described. The optical and electronic systems are housed in a truck with a retractable rooftop transmission and receiving mirror, connected to a 40-cm-diameter vertically looking telescope. Two injection-seeded Nd:YAG lasers are employed in connection with an optical parametric oscillator-optical parametric amplification transmitter, allowing deep-UV to mid-IR wavelengths to be generated. Fast switching that employs piezoelectric drivers allows multiwavelength differential absorption lidar for simultaneous measurements of several spectrally overlapping atmospheric species. The system can also be used in an imaging multispectral laser-induced fluorescence mode on solid targets. Advanced LabVIEW computer control and multivariate data processing render the system versatile for a multitude of measuring tasks. We illustrate the monitoring of industrial atmospheric mercury and hydrocarbon emissions, volcanic sulfur dioxide plume mapping, fluorescence lidar probing of seawater, and multispectral fluorescence imaging of the facades of a historical monument.