gebhart/patrepeval huggingface dataset:
137. INFLUENCE OF THE PREOPERATIVE DISC HEIGHT ON THE RESULTS OF LUMBAR DISC PROSTHESES (2011)

Purpose of the study: Indications for disc prosthesis is generally established on the basis of the MRI findings (MODIC classification) and the discography. We considered that knowledge of the preoperative disc height is also important. We report a multicentric study of the results of lumbar arthroplasties as a function of preoperative height of the operated disc. Material and methods: A Mobidisc prosthesis was implanted in 93 patients and followed prospectively for at least one year (mean follow-up 5 years). Disc height was compared with the height of the suprajacent disc and divided into three groups: > 66% of height (GI) i.e. a subnormal disc height (n=30), 33–66% (GII) moderate impingement (n=36), Results: The lumbar VAS improved from 6.7 to 3.2 (GI), 6.2 to 2 (GII) and 6.2 to 1.5 (GIII). The radicular VAS improved from 4.8 to 3.1 (GI), 5.7 to 2.4 (GII) and 5.5 to 1.6 (GIII), respectively 69, 75 and 85.5% of the patients were satisfied or very satisfied for relief of the lumbar or radicular pain. The Oswestry score improved from 50 to 22% (GI), 49 to 20% (GII) and 46 to 12% (GIII). By MODIC, the lumbar VAS improved from 6.5 to 2.8 (MODIC 0) and from 6.6 to 2 (MODIC 1). The radicular VAS was improved from 5.5 to 2.9 (MODIC 0) and from 5.3 to 2.1 (MODIC 1). The Oswestry score was improved from 52 to 24% (MODIC 0) and from 48 to 15% (MODIC 1). Independently of MODIC, the VAS was always better for very tight discs and lower if the disc height was preserved. Discussion: An influence of the disc height was found for all parameters studied, irrespective of the type of disc disease as described by the MODIC classification. The presence of a tight preoperative disc height appeared as the essential prognostic factor for discal prostheses. For a MODIC 0 discopathy, without loss of disc height, only 67 and 61% of the operated patients were satisfied or very satisfied with relief of lumbar and radicular pain (VAS 3.6 and 3.4) for respectively 88 and 75% of the MODIC0 discopathies with discal impingement (VAS 1.5 and 1.5). Though it should not be formally ruled out, surgery for discopathy with a preserved disc height should be examined prudently before implanting a disc prosthesis.
Vibrational spectra and structure of poly(dialkylaminophosphazene)s (2002)

The IR and Raman spectra of poly(dialkylaminophosphazene)s (PDAAPs) [-P(NHC m H 2m+1 ) 2 =N-] n with m = 1-7 were measured in the temperature range from -100 to +20°C and at room temperature, respectively. Vibrational modes in the spectra of PDAAPs were assigned with reference to the previously obtained spectral data on poly(dialkoxyphosphazene)s. The absence of conformational transitions due to rotation about the P-N and C-N bonds in the side groups was demonstrated for all the poly(dialkylaminophosphazene)s examined. Temperature-induced variations in the IR spectra of PDAAPs with m > 4 are due to the gauche-trans transitions resulting from internal rotation about C-C bonds in the side groups, as well as to changes in the backbone structure. No changes in the main-chain structure were observed for PDAAPs with m ≤ 4 because of the hydrogen bonds formed by NH groups.
Revision Total Hip Arthroplasty in Octogenarians (2007)

Revision total hip arthroplasty can provide substantial clinical benefit to patients over eighty years of age. The medical complication rate for octogenarians may not differ significantly from that for patients seventy years of age or younger, and the prevalence of technical complications and dislocations can be expected to be lower than that for younger patients.
Review of the West Indian Astraptes xagua (Lucas) complex (Hesperiidae: Eudaminae) with the description of a new subspecies from the Bahamas (2016)

A.slraple.s xagua (Lucas) is one of six species within the genus recorded from Cuba, Hispaniola, and the Bahamas in the West Indies. Although Steinhauser and J.Y. Miller completed a review of Astraple.s based on morphological characters, the advent of molecular phylogenetic analysis provides further insight into the current status of the Astraptes xagua complex. We reinstate A. rhrulyi (Sharpe) as a species-level taxon based on the differences in genitalia and CO/barcodes, and describe a new subspecies, A. xagua harveyi Clench, Steinhauser and J. Y. Miller, type locality North Andros Island, Bahamas. Thus, the A. xagua complex consists of two species, one of which is divided into two subspecies.
HYDROGENOLYSIS OF ALCOHOLS TO HYDROCARBONS (1933)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHYDROGENOLYSIS OF ALCOHOLS TO HYDROCARBONSBruno Wojcik and Homer AdkinsCite this: J. Am. Chem. Soc. 1933, 55, 3, 1293–1294Publication Date (Print):March 1, 1933Publication History Published online1 May 2002Published inissue 1 March 1933https://doi.org/10.1021/ja01330a506RIGHTS & PERMISSIONSArticle Views242Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (155 KB) Get e-Alerts Get e-Alerts
Clustering unlabeled data with SOMs improves classification of labeled real-world data (2003)

We show the use of a self organizing map to cluster unlabeled data and to infer possible labelings from the clusters. Our inferred labels are presented to a multilayer perceptron along with labeled data, performance is improved over using only the labeled data. Results are presented for a number of popular real-world benchmark problems from domains other than text. This shows one way in which unlabeled data can be used to enhance supervised learning in a general-purpose neural network.
Collision-Balancing Frequency Hopping in Single-Hop Mobile Ad Hoc Networks (2012)

We consider a single-hop frequency hopping (FH) mobile ad hoc network (MANET). To increase throughput orthogonal FH (O-FH) with hop-synchronous hopping can be used, thereby allowing collision-free transmissions under certain circumstances. However, as the MANET grows, hopping sequences must be re-used. As a result, nodes sharing the same sequence will experience deterministic collisions while others having a unique sequence will still communicate collision-free. This results in an \emph{unfair} interference situation and makes performance guarantees difficult to meet for all nodes simultaneously. In this paper, we propose a \emph{collision-balancing} FH (CB-FH) scheme to overcome this drawback. The CB scheme builds on O-FH and adapts the sequence set to balance interference among the nodes. We analytically study the characteristics of the adaptive sequences and analyze the resulting interference situation at the nodes. The performance is compared to uncoordinated FH (U-FH) and O-FH. It is found that CB-FH solves the problem of unfairness present in O-FH. Compared to U-FH, CB-FH yields considerable improvements in a wide range. Practical issues are discussed.
Effect of source and drain junctions on plasma charging (1998)

Threshold voltage and subthreshold swing were used to study the effect of potential developed at source and drain junctions on gate oxide damage during plasma processing-induced wafer charging. During substrate injection, when the junctions are reverse-biased, the damage is higher. On the other hand, during gate injection the gate oxide damage is significantly reduced once the source and drain junctions become forward-biased. Hot carrier lifetime measurements also confirm this behaviour.
Physician approval for pregnancy in patients with SLE showing only serological activity: A vignette survey study (2022)

Abstract Background: The EULAR recommendation requires that the disease activity of systemic lupus erythematosus before pregnancy be stable because pregnancy complications and disease flares increase if pregnancy occurs while systemic lupus erythematosus activity is high. However, some patients have ongoing serological activity even after treatment. Herein, we aimed to investigate how physicians make decisions on the acceptability of pregnancy when patients with systemic lupus erythematosus only have serological activity. Methods: A questionnaire was administered online to physicians from December 2020 to January 2021. It included the characteristics of physicians, facilities, and the allowance for pregnancies for patients with systemic lupus erythematosus using vignette scenarios. Results: The questionnaire was distributed to 4,946 physicians, and 9.4% of physicians responded. The median age of respondents was 46 (range: 38–54) years, and 85% were rheumatologists. Pregnancy allowance was significantly affected by duration of the stable period, and mild or high serological activity, respectively (duration: proportion difference, 11.8 percentage points [p.p.]; p &lt; 0.001; mild: proportion difference, -25.8 p.p; p &lt; 0.001; high: -65.6 p.p.; p &lt; 0.001). Even though patients had a high level of serological activity, 20.5% of physicians allowed pregnancy if there were no clinical symptoms for six months. Conclusions: Serological activity had a significant effect on physician judgment on the acceptability of pregnancy. Conversely, some physicians allowed patients who only had serological activity to become pregnant. Further observational studies are required to clarify the prognosis of such patients.
Sample Reduction and Subsequent Adaptive Interpolation of Speech Signals (1983)

In this paper we investigate the effect of rejecting every nth speech sample and replacing it by means of adaptive interpolation. The interpolation procedure attempts to minimize the mean square interpolation error by recomputing the autocorrelation function of the speech sequence every W samples. We describe three methods of computing the correlation function. An iterative procedure is evaluated for estimating the correlation function of a speech sequence whose every nth sample has been discarded. For speech bandlimited to 3.2 kHz, sampled at 8 kHz, and n = 4, W = 256, the gain in signal-to-noise ratio (s/n) achieved by adaptive interpolation compared to nearest neighbor average interpolation was 14 and 8 dB, depending on whether the correlation function was computed from the original speech, or by using the iterative procedure, respectively. The effect of varying n from 2 to 6 was also investigated. Finally, we applied the interpolation procedures to 8-bit μ-law pulse code modulation (PCM), μ = 255, reducing 64 kb/s transmission to 48 kb/s by rejecting one PCM word in four. The recovered speech after interpolation had a s/n that approximated that of conventional 56 kb/s μ-law PCM speech.
Levamisole induced necrosis of the skin and neutropenia following intranasal cocaine use: a newly recognized syndrome. (2011)

Levamisole is a veterinary anti-helminthic used to treat several autoimmune conditions but also commonly utilized as an additive in cocaine distribution. Toxicity resulting in agranulocytosis and cutaneous necrosis in association with cocaine use is an infrequently described phenomenon of an emerging problem. Although levamisole is found extensively in the cocaine supply of the United States, relatively few cases of necrotic skin lesions associated with intranasal use have been reported. The skin necrosis secondary to levamisole toxicity is characterized by variable findings on biopsy, ranging from leukocytoclastic vasculitis to occlusive vasculopathy. The following case describes a 54-year-old male who developed fever, agranulocytosis, p-ANCA autoantibodies and extensive skin necrosis following heavy intranasal cocaine use. Necrosis of greater than 50% of the patient's total body surface area resulted and was followed by thorough wound debridement.
Arsenic targets tubulins to induce apoptosis in myeloid leukemia cells. (1999)

Arsenic exhibits a differential toxicity to cancer cells. At a high concentration (>5 microM), As2O3 causes acute necrosis in various cell lines. At a lower concentration (0.5-5 microm), it induces myeloid cell maturation and an arrest in metaphase, leading to apoptosis. As2O3-treated cells have features found with both tubulin-assembling enhancers (Taxol) and inhibitors (colchicine). Prior treatment of monomeric tubulin with As2O3 markedly inhibits GTP-induced polymerization and microtubule formation in vitro but does not destabilize GTP-induced tubulin polymers. Cross-inhibition experiments indicate that As2O3 is a noncompetitive inhibitor of GTP binding to tubulin. These observations correlate with the three-dimensional structure of beta-tubulin and suggest that the cross-linking of two vicinal cysteine residues (Cys-12 and Cys-213) by trivalent arsenic inactivates the GTP binding site. Furthermore, exogenous GTP can prevent As2O3-induced mitotic arrest.
Artificial Metalloenzymes: Combining the Best Features of Homogeneous and Enzymatic Catalysis (2009)

By combining homogeneous with enzymatic catalysis, artificial metalloenzymes offer new perspectives for conferring unnatural activities to biomolecules. The article reassembles the important advances in the field of these hybrid catalysts and summarizes the contributions of our group to this continuously growing field of research.
An Adaptive Vertical Handover in Service Specific Overlay Networks (2012)

This paper proposes a new vertical handover (VHO)-enhanced mobile service discovery and composition method over a hybrid service overlay network (H-SON). The overlay considers the dynamic characteristics of mobile nodes in the decision for node placement as well as the types of services provided and Quality of Service (QoS) levels. The mobile nature of media clients provokes a necessity to consider VHO operations to meet the requirements of offered service level agreements (SLAs). The integrated framework continuously derives optimal VHO configuration policies with respect to handover initiation and network selection for service specific overlay network (SSON) node migration. The VHO-enhanced service composition method allows for efficient, accurate, and QoS-aware component service discovery, composition, and execution. We demonstrate that our approach provides better performance and reduced composition delay in heterogeneous network environments when compared to other service-composition solutions.
Li Storage Feasibility of Defected Single- and Bi-Layer Graphene (2015)

The limited capacity of the intercalation-type graphitic materials has lead to much effort to explore new electrode materials. A natural choice among the carbonaceous materials, graphene, has attracted increased attention for obtaining higher Li storage capacity. The outstanding mechanical strength, electronic conductivity, and ready availability of extra storage sites for Li, has suggested that this material could be an ideal platform for storing more Li. However, for wide range of Li coverages, the calculations predict that defect-free single layer graphene is not thermodynamically favorable for lithiation compared to bulk metallic Li. Thus, exploring ways with which graphene surfaces can be activated such that Li storage capacity can be improved has become a significant focus of research in the field. One such strategy is to activate graphene surface with structural defects. Generally speaking, structural defects can be found nearly in all carbonaceous materials. The presence of such defects can be detrimental for the performance of graphene-based devices. In contrast, however, deviations from the perfection of atomic lattice can also be useful for some applications, as they make it possible to tailor the properties leading to new functionalities. Following this approach, we performed an extensive series of density functional theory (DFT) calculations for Li adsorption and intercalation in single and bi-layer graphene, which are activated by topological defects for improving Li adsorption. The results confirm that Li adsorption on defect-free single layer graphene is not thermodynamically favorable compared to bulk metallic Li. However, graphene surfaces activated by structural defects are generally found to bind Li more strongly, with the interaction strength sensitive to both the nature of the defects and their densities. The interaction of Li with a one-dimensional extended defect is additionally found to be strong, improving Li storage capacity. The theoretical Li storage capacities of the defected single-layer graphene structures are evaluated with a rigorous thermodynamic analysis, which establishes, in some cases, that these capacities approach, although not exceed, those of graphite. Li storage in bi-layer graphene with and without defects are evaluated in a similar way, and indicate more favorable interaction, and promise for higher Li storage than that of single layer graphene. We will present performance comparisons between defected single- and bi-layer graphene structures, and bulk-graphite for Li storage capacities. A detailed analysis of the effect of the van der Walls (vdW) interactions will also be presented.
Single-incision laparoscopic surgery: an update of current evidence (2016)

Single-incision laparoscopic surgery (SILS), especially for appendicectomy, colectomy, and cholecystectomy has attracted certain attention. They have the potential to improve patient satisfaction from “scar-free” cosmesis, decrease surgical trauma and reduce post-operative pain, and may hasten recovery. This article aims to review the current evidence regarding SILS for these three commonly indicated operations.
Introducing an Inverted Classroom Concept for an Undergraduate Course in Power Electronics – Implementation, Evaluation and Experiences (2019)

In this article, the experiences gained from introducing an inverted classroom concept for an undergraduate power electronics course, based on online videos instead of traditional classroom methods, are described. Organization and implementation of the course are discussed. Limitations and opportunities are examined. Effectiveness of the inverted classroom approach is compared to a traditional course design, based on student perception and students performance evaluation. Results show that a high student satisfaction rate and learning outcome, comparable to a traditional lecture, can be achieved using the inverted classroom approach in the here presented case.
A common origin of the 4143insA ADAMTS13 mutation (2006)

Severely deficient activity of the von Willebrand Factor (VWF) cleaving metalloprotease, ADAMTS13, is associated with thrombotic thrombocytopenic purpura (TTP). The mutation spectrum ofADAMTS13 is rather heterogeneous, and numerous mutations spread across the gene have been described in association with congenital TTP. The 4143insA mutation is unusual with respect to its geographic concentration. Following the initial report from Germany in which the 4143insA mutation was detected in four apparently unrelated families, we have now identified this mutation in a further eleven patients from Norway, Sweden, Poland, Germany, the Czech Republic and Australia. Confirmation that the Australian patient is of German ancestry, together with the Northern and Central European origin of most of the other patients, suggests that the 4143insA mutation has a common genetic background. We established ADAMTS13 haplotypes by analyzing 17 polymorphic intragenic markers. The haplotypes linked to 4143insA were identical in all informative families. Three novel candidate mutations, C347S, P671L and R1060W, as well as the known mutation R507Q, were also identified during the course of the study. We conclude that 4143insA has a common genetic background and is frequent among patients with hereditary ADAMTS13 deficiency in Northern and Central European countries.
Inhibition of thalamic excitability by 4,5,6,7‐tetrahydroisoxazolo[4,5‐c]pyridine‐3‐ol: a selective role for δ‐GABAAreceptors (2009)

The sedative and hypnotic agent 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine-3-ol (THIP) is a GABA(A) receptor (GABA(A)R) agonist that preferentially activates delta-subunit-containing GABA(A)Rs (delta-GABA(A)Rs). To clarify the role of delta-GABA(A)Rs in mediating the sedative actions of THIP, we utilized mice lacking the alpha(1)- or delta-subunit in a combined electrophysiological and behavioural analysis. Whole-cell patch-clamp recordings were obtained from ventrobasal thalamic nucleus (VB) neurones at a holding potential of -60 mV. Application of bicuculline to wild-type (WT) VB neurones revealed a GABA(A)R-mediated tonic current of 92 +/- 19 pA, which was greatly reduced (13 +/- 5 pA) for VB neurones of delta(0/0) mice. Deletion of the delta- but not the alpha(1)-subunit dramatically reduced the THIP (1 mum)-induced inward current in these neurones (WT, -309 +/- 23 pA; delta(0/0), -18 +/- 3 pA; alpha(1) (0/0), -377 +/- 45 pA). Furthermore, THIP selectively decreased the excitability of WT and alpha(1) (0/0) but not delta(0/0) VB neurones. THIP did not affect the properties of miniature inhibitory post-synaptic currents in any of the genotypes. No differences in rotarod performance and locomotor activity were observed across the three genotypes. In WT mice, performance of these behaviours was impaired by THIP in a dose-dependent manner. The effect of THIP on rotarod performance was blunted for delta(0/0) but not alpha(1) (0/0) mice. We previously reported that deletion of the alpha(1)-subunit abolished synaptic GABA(A) responses of VB neurones. Therefore, collectively, these findings suggest that extrasynaptic delta-GABA(A)Rs vs. synaptic alpha(1)-subunit-containing GABA(A)Rs of thalamocortical neurones represent an important molecular target underpinning the sedative actions of THIP.
The synergistic effect of dicyandiamide and resorcinol in the curing of epoxy resins (2003)

Abstract The synergistic effect of dicyandiamide (Dicy) and phenolic substances was studied, with resorcinol as a model compound. It was found that when Dicy and resorcinol are used jointly, the curing temperature of epoxy resin can be significantly lowered. FTIR and DSC data were used to illustrate the mechanism of the synergism. The addition of the phenolic hydroxyl group to epoxide was facilitated by Dicy, which favors the formation of phenoxy anions. The reaction of Dicy with epoxide was facilitated by resorcinol, which can exert “electrophilic assistance” for the addition of the amino group to epoxide. The presence of resorcinol also favors the addition of the hydroxyl group to the cyano group. The thermal and mechanical properties of the epoxy resins cured with Dicy/resorcinol or Dicy/phloroglucinol were studied. © 2003 Wiley Periodicals, Inc. J Appl Polym Sci 89: 1869–1874, 2003