gebhart/patrepeval huggingface dataset:
A Priori Data and A Posteriori Decision Fusions for Human Action Recognition (2016)

In this paper, we tackle the challenge of human action recognition using multiple data sources by mixing a pri-ori data fusion and a posteriori decision fusion. Our strategy applied from 3 main classifiers (Dynamic Time Warping, Multi-Layer Perceptron and Siamese Neural Network) using several decision fusion methods (Voting , Stacking, Dempster-Shafer Theory and Possibility Theory) on two databases (MHAD (Ofli et al., 2013) and ChAirGest (Ruffieux et al., 2013)) outperforms state-of-the-art results with respectively 99.85% ± 0.53 and 96.40% ± 3.37 of best average correct classification when evaluating a leave-one-subject-out protocol.
Multipotential Stromal Cell Abundance in Cellular Bone Allograft: Comparison with Fresh Age-Matched Iliac Crest Bone and Bone Marrow Aspirate (2014)

Cellular allograft bone represents a unique nonimmune material rich in MSCs and osteocytes. This osteoinductive graft represents an attractive alternative to autograft bone or composite/synthetic grafts in orthopedics and broader regenerative medicine settings.
Monitoring Peer to Peer Systems (2007)

In this paper, we are concerned with the distributed monitoring of P2P systems. We introduce the P2P Monitor system and a new declarative language, namely P2PML, for specifying monitoring tasks. A subscription is compiled into a distributed algebraic plan which is described using an algebra over XML streams. We introduce a filter for streams of XML documents that scales by processing first simple conditions and then, if still needed, evaluating complex queries. We also show how particular tasks can be supported by identifying subtasks already provided by existing streams.
Synthesis and characterization of poly(ε‐caprolactone)‐containing amino acid‐based poly(ether ester amide)s (2011)

Abstract A new family of biodegradable amino acid‐based poly(ether ester amide)s (AA‐PEEAs) consisting of three building blocks [poly(ε‐caprolactone) (PCL), L ‐phenylalanine (Phe), and aliphatic acid dichloride] were synthesized by a solution polycondensation. Using DMA as the solvent, these PCL‐containing Phe‐PEEA polymers were obtained with fair to very good yields with weight average molecular weight ( M w ) ranging from 6.9 kg/mol to 31.0 kg/mol, depending on the original molecular weight of PCL. The chemical structures of the PCL‐containing Phe‐PEEA polymers were confirmed by IR and NMR spectra. These PCL‐containing Phe‐PEEAs had lower T g than most of the oligoethylene glycol (OEG) based AA‐PEEAs due to the more molecular flexibility of the PCL block in the backbones, but had higher T g than non‐amino acid based PEEA. The solubility of the PCL‐containing Phe‐PEEA polymers in a wide range of common organic solvents, such as THF and chloroform, was significantly improved when comparing with aliphatic diol based poly(ester amide)s and OEG based AA‐PEEAs. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Mass production. (2005)

This chapter presents various technologies for the in vivo (culture of entomophilic nematodes in insect hosts) and in vitro (Dauer juvenile and recovery, solid-phase production, liquid culture, and liquid culture process technology) production of entomophilic nematodes, and describes the developmental biology of entomophilic nematodes in liquid media. Research on Steinernema and Heterorhabditis spp. is largely covered.
DEVELOPMENT UNDER EXTREME CONDITIONS: FORENSIC BIOINFORMATICS IN THE WAKE OF THE WORLD TRADE CENTER DISASTER (2002)

The terrorist attacks of September 11, 2001 resulted in death and devastation in three locations, and extraordinary efforts have been exerted to identify the remains of all victims. As mass fatalities go, this one has been unusual at a policy level because the goal has been not merely to identify remains for every decedent, but to identify every bit of remains found so that even small pieces of tissue can be returned to families for burial. While the human impact at the Pentagon and Shanksville, PA was horrific, the World Trade Center site presented a particularly complex challenge for forensic DNA matching and data handling. A complete and definitive list of all those killed is still elusive, and human remains were crushed and co-mingled by the falling towers. Software tools had never been considered for a problem of this scale and scope. New data handling systems had to be created under extreme software development conditions characterized by incomplete requirements specifications, chaotically changing priorities, truly impossible deadlines and rapidly rolling production releases. Partly because of the company's experience with mtDNA tools built for the Armed Forces DNA Identification Lab starting in 1997, the New York City Office of Chief Medical Examiner [OCME] contacted Gene Codes Corporation in late September as existing data-handling tools began to fail. We began work on the project in mid-October, 2001. Our approach to the problem included: Extreme Programming [XP] methodology for functional software development, On-site time and motion analysis at the OCME for user interface design, Evidentiary references between STR, SNP and mtDNA analysis results, and Separate data Quality Control [QC] and software Quality Assurance [QA] initiatives. A substantial software suite was developed called M-FISys, an acronym for Mass-Fatality Identification System.
American Democracy: The View From Scotland, 1776–1832 (1974)

The American democratic model was utilized by Scottish reformers and conservatives who saw in American events a confirmation of their own ideas and hopes. The ideals articulated by the American Revolution and the political institutions created in the new nation were analyzed as matters that impinged on the deepest commitments of Scottish intellectuals. Conservatives perceived America as a threat to the stability and continuance of British political tradition, which they saw as dependent upon the preservation of Scotland's distinctive national past. The American experience was significant to reformers of all persuasions because it invested their discursive thought with a reality it had not known before. Yet American principles and precepts were not determinative, but rather were used to convey certain carefully selected ideas. As Adam Ferguson, one of Scotland's brightest enlightenment minds, noted, “If nations actually borrow from their neighbors, they probably borrow only what they are nearly in a condition to have invented themselves.” America was useful to Scottish political thinkers because Britain was ready to “invent” her own political forms. The differences that divided Scotland's most articulate political writers were fundamental. The conservatives firmly believed that man's brutish nature required restraints, an established church, a balanced hierarchical social-political order, and stability. Radical Scots argued that with freedom and democratic institutions society would be humane and prosperous. Reformers spoke out against the worst social evils: they advocated Catholic emancipation, abolition of the slave trade, an end to flogging in the army and navy, prison reform and, in 1832, the extension of the franchise to the middle class.
Insulinotropic Glucagon-Like Peptide I Receptor Expression in Glucagon-Producing α-Cells of the Rat Endocrine Pancreas (1997)

Glucagon-like peptide I (GLP-I), an intestine-derived incretin hormone, is a potent stimulator of insulin and somatostatin secretion. In some studies, GLP-I is an inhibitor of glucagon secretion. It remains uncertain, however, whether the effect of GLP-I on the inhibition of glucagon secretion is direct, owing to interactions with GLP-I receptors on alpha-cells, or indirect, via paracrine suppression by insulin or somatostatin. The localization of the GLP-I receptor on insulin and somatostatin-producing cells in the islets is well established. Whether the GLP-I receptor also resides on the glucagon-producing alpha-cells remains controversial and is reported to be absent on rat alpha-cells. To investigate the distribution of the GLP-I receptor on islet cells, we examined the expression of GLP-I receptor mRNA in phenotypically distinct islet cell lines and islets, and the presence of immunoreactive GLP-I receptor in dispersed rat islet cells using a specific antiserum. GLP-I receptor mRNA was readily detected by reverse transcription-polymerase chain reaction (RT-PCR) in both rat islets and in established islet cell lines representing distinct alpha-, beta-, and delta-cell phenotypes. In addition, GLP-I receptor expression was detected in single rat alpha-cells by single-cell RT-PCR. In dispersed rat islet cells analyzed by double immunofluorescent staining, 90% of the insulin, 76% of the somatostatin, and 20% of the glucagon positive cells colocalized with the GLP-I receptor immunoreactivity. Thus, a substantial population of glucagon immunoreactive a-cells express the GLP-I receptor. These findings imply that GLP-I may have a direct receptor-mediated action in the regulation of the physiological functions on a substantial subpopulation of alpha-cells. We suggest that a possible role for GLP-I receptors on alpha-cells may be to provide positive autocrine feedback control on glucagon secretion during fasting and/or to dampen the potent paracrine suppression of glucagon secretion by insulin during feeding.
Anti‐inflammatory effects of cannabinoid CB2 receptor activation in endotoxin‐induced uveitis (2013)

This article is part of a themed section on Cannabinoids 2013. To view the other articles in this section visit http://dx.doi.org/10.1111/bph.2014.171.issue-6.
Selective and reversible effects of vinca alkaloids onTrypanosoma cruzi epimastigote forms: Blockage of cytokinesis without inhibition of the organelle duplication (1999)

Vinca alkaloids, vincristine and vinblastine, produce differential effects on the cell division of Trypanosoma cruzi epimastigote forms depending on drug concentrations. These effects are related to different microtubule-based mechanisms. For 15 microM vinblastine and 50 microM vincristine, the drugs inhibit both nuclear division and cytokinesis, and affect cell shape. At 3 microM vinblastine and 10 microM vincristine, however, cytokinesis is inhibited without major effect on the progression of the cell cycle; this yields giant cells having multiple nuclei, kinetoplasts and flagella. Cultures maintained over 1 week with daily drug replacement produced cells with more than 16 nuclei and 24 kinetoplasts, indicating that an equivalent of a fifth cell cycle was initiated. The ultrastructure of the multinucleate cells showed a basic organization closely similar to that of trypanosomes. Cytokinesis inhibition by vinca alkaloids seems to result from modulations of interactions between microtubules and associated proteins, rather than from an inhibition of microtubule dynamics as is usually proposed for vinca alkaloids. Cytokinesis inhibition is reversible: after removing the drug, epimastigotes emerge from the multinucleate cells. The emerging process follows a precise axis and polarity which are determined by the position of the flagellum/kinetoplast complex. This region could play an essential role in cell morphogenesis since zoids (cells without a nucleus) are frequently observed.
Joint effect of HSD3B1 and HSD3B2 genes is associated with hereditary and sporadic prostate cancer susceptibility. (2002)

3beta-hydroxysteroid dehydrogenases (HSD3Bs), encoded by the HSD3B gene family at 1p13, have long been hypothesized to have a major role in prostate cancer susceptibility. The recent reports of a prostate cancer linkage at 1p13 provided additional evidence that HSD3B genes may be prostate cancer susceptibility genes. To evaluate the possible role of HSD3B genes in prostate cancer, we screened a panel of DNA samples collected from 96 men with or without prostate cancer for sequence variants in the putative promoter region, exons, exon-intron junctions, and 3'-untranslated region of HSD3B1 and HSD3B2 genes by direct sequencing. Eleven single nucleotide polymorphisms (SNPs) were identified, four of which, including a missense change (B1-N367T), were informative. These four SNPs were further genotyped in a total of 159 hereditary prostate cancer probands, 245 sporadic prostate cancer cases, and 222 unaffected controls. Although a weak association between prostate cancer risk and a missense SNP (B1-N367T) was found, stronger evidence for association was found when the joint effect of the two genes was considered. Men with the variant genotypes at either B1-N367T or B2-c7519g had a significantly higher risk to develop prostate cancer, especially the hereditary type of prostate cancer. Most importantly, the subset of hereditary prostate cancer probands, whose families provided evidence for linkage at 1p13, predominantly contributed to the observed association. Additional studies are warranted to confirm these findings.
EC06-783 Watermark Granular Matrix Sensor to Measure Soil Matric Potential for Irrigation Management (2006)

Extension Circular 06-783 discusses Watermark Granular Matrix Sensor to Measure Soil Matric Potential for Irrigation Management.
Subcellular Localization of Acyl-CoA: Lysophosphatidylethanolamine Acyltransferases (LPEATs) and the Effects of Knocking-Out and Overexpression of Their Genes on Autophagy Markers Level and Life Span of A. thaliana (2021)

<i>Arabidopsis thaliana</i> possesses two acyl-CoA:lysophosphatidylethanolamine acyltransferases, LPEAT1 and LPEAT2, which are encoded by <i>At1g80950</i> and <i>At2g45670</i> genes, respectively. Both single <i>lpeat2</i> mutant and double <i>lpeat1 lpeat2</i> mutant plants exhibit a variety of conspicuous phenotypes, including dwarfed growth. Confocal microscopic analysis of tobacco suspension-cultured cells transiently transformed with green fluorescent protein-tagged versions of LPEAT1 or LPEAT2 revealed that LPEAT1 is localized to the endoplasmic reticulum (ER), whereas LPEAT2 is localized to both Golgi and late endosomes. Considering that the primary product of the reaction catalyzed by LPEATs is phosphatidylethanolamine, which is known to be covalently conjugated with autophagy-related protein ATG8 during a key step of the formation of autophagosomes, we investigated the requirements for LPEATs to engage in autophagic activity in Arabidopsis. Knocking out of either or both <i>LPEAT</i> genes led to enhanced accumulation of the autophagic adaptor protein NBR1 and decreased levels of both <i>ATG8a</i> mRNA and total ATG8 protein. Moreover, we detected significantly fewer membrane objects in the vacuoles of <i>lpeat1 lpeat2</i> double mutant mesophyll cells than in vacuoles of control plants. However, contrary to what has been reported on autophagy deficient plants, the <i>lpeat</i> mutants displayed a prolonged life span compared to wild type, including delayed senescence.
Consenting to Donate Organs: Whose Wishes Carry the Most Weight? (1991)

An experimental simulation methodology examined how people weigh the wishes of the donor and the next‐of‐kin in recommending whether the latter should consent to donate the organs of a deceased loved one. Subjects read several brief stories, each describing a young adult who had died suddenly and whose kin faced the decision of whether to donate their loved one's organs. Each scenario had four versions, identical except for minor wording changes providing information about the organ donation wish of the potential donor and the next‐of‐kin. Subjects indicated “yes,”“no,” or “I'm undecided” about whether the kin should donate the organs. Subjects weighted the wishes of the deceased much more heavily than their own or those of the next‐of‐kin when those wishes were stated directly. When the deceased's wishes had to be inferred indirectly, attitudes of the next‐of‐kin and the experimental subject affected the decision much more. Implications for organ procurement practice are considered.
Development of a Novel, Highly Efficient Halide-Catalyzed Sulfenylation of Indoles (2006)

[reaction: see text] The reaction of a variety of indoles with N-thioalkyl- and N-thioarylphthalimides to produce 3-thioindoles is reported. Catalytic quantities of halide-containing salts are crucial to the success of this reaction. This highly efficient reaction provides sulfenylated indoles from bench-stable, readily available starting materials in good to excellent yields.
Influenza Virus-Induced Paracrine Cellular Senescence of the Lung Contributes to Enhanced Viral Load (2023)

Aging is a major risk factor associated with increased morbidity and mortality rates observed during respiratory infections. In this study, we investigated the role of influenza virus infections in the establishment of premature cellular senescence and paracrine macrophage-activated inflammation. We observed in our murine model a premature aging by the appearance of senescent cells in the lungs after 21 d of influenza A virus infection. By using murine ex vivo lung models, the influence of TNF-α on the establishment of cellular senescence was detectable. Our findings were proven by using conditioned media of infected human monocyte-derived macrophages on primary lung fibroblasts. Here, a distinct expression of senescence-associated parameters could be confirmed. Furthermore, senescent cells in the lungs strongly influenced subsequent viral infections. Our data demonstrated a higher viral load in senescent primary lung fibroblasts, indicating an intracellular effect on viral replication. Transcriptomic data revealed an increased regulation of JAK/STAT signaling in senescent IAV-infected cells accompanied with increased TRAIL expression. Additionally, senescent cells indicating low pH values, accelerating viral replication. Our study provides new insights into pathomechanisms of virus-induced cellular senescence. Hence, IAV infection induces premature senescence and subsequent infections in senescent cells lead to an increased viral replication.
Periodic Nanoporous Inorganic Patterns Directly Made by Self‐Ordering of Cracks (2022)

Solution-processed inorganic nanoporous films are key components for the vast spectrum of applications ranging from dew harvesting to solar cells. Shaping them into complex architectures required for advanced functionality often needs time-consuming or expensive fabrication. In this work, crack formation is harnessed to pattern porous inorganic films in a single step and without using lithography. Aqueous inks, containing inorganic precursors and polymeric latexes enable evaporation-induced, defect-free periodic arrays of cracks with tunable dimensions over several centimeters. The ink formulation strategy is generalized to more than ten inorganic materials including simple and binary porous oxide and metallic films covering a whole spectrum of properties including insulating, photocatalytic, electrocatalytic, conductive, or electrochromic materials. Notably, this approach enables 3D self-assembly of cracks by stacking several layers of different compositions, yielding periodic assemblies of polygonal shapes and Janus-type patterns. The crack patterned periodic arrays of nanoporous TiO<sub>2</sub> diffract light, and are used as temperature-responsive diffraction grating sensors. More broadly, this method represents a unique example of a self-assembly process leading to long-range order (over several centimeters) in a robust and controlled way.
Coherent lidar at low signal powers: Basic considerations on optical heterodyning (1998)

Abstract In a number of optical heterodyne systems it may happen that the signal power is so low that only a few, or even fractions of, photons enter the receiver in a characteristic time interval. As the heterodyne receiver basically employs the beating effect, such intricate questions as “is there still a beating between the (many) local oscillator photons and the few return photons?” or “how can a single photon produce an intermediate frequency?” arise. We show that the semiclassical theory, which provides exact results as long as optical fields with an adequate classical description are used, is capable of answering those questions. The term “photon” must thereby be assigned its (semiclassically) correct meaning, which is an abbreviation for “discrete interaction of light and matter.” We illustrate our discussion by providing a numerical example related to a space-borne CO2 Doppler wind lidar instrument.
Ongoing work on CAEV project in the veterinary school of Lyon group. (1998)

International audience
Fabrication of Complex integrated Waveguide filters using Electron Beam Lithography (1998)

Integrated waveguide filters have recently been used in many optical processing applications including the filtering[1] multiplexing[2] and switching[3] of optical signals. In particular chirped grating have been for dispersion compensation in optical fiber systems[4] and apodization is commonly used to suppress the production of sidelobes in the transmission characteristics of grating filters. It is envisaged that in the future telecommunications and optical computing networks will require novel and complex grating structures for the processing and selective switching applications in multi-channel systems. Therefore, a simple and reliable method for the production of grating filters, where the filter charcteristics can be easily tailored is desired. In this letter we describe a single step, electron beam based approach, where the grating and waveguide are defined simultaneously and the grating characteristics arc well controlled.
System and method to create three-dimensional images of non-linear acoustic properties in a region remote from a borehole (2023)

In some aspects of the disclosure, a method for creating three-dimensional images of non-linear properties and the compressional to shear velocity ratio in a region remote from a borehole using a conveyed logging tool is disclosed. In some aspects, the method includes arranging a first source in the borehole and generating a steered beam of elastic energy at a first frequency; arranging a second source in the borehole and generating a steerable beam of elastic energy at a second frequency, such that the steerable beam at the first frequency and the steerable beam at the second frequency intercept at a location away from the borehole; receiving at the borehole by a sensor a third elastic wave, created by a three wave mixing process, with a frequency equal to a difference between the first and second frequencies and a direction of propagation towards the borehole; determining a location of a three wave mixing region based on the arrangement of the first and second sources and on properties of the third wave signal; and creating three-dimensional images of the non-linear properties using data recorded by repeating the generating, receiving and determining at a plurality of azimuths, inclinations and longitudinal locations within the borehole. The method is additionally used to generate three dimensional images of the ratio of compressional to shear acoustic velocity of the same volume surrounding the borehole.
Frentes de expansão na Amazônia: uma perspectiva geográfico-histórica (1988)

Frentes de expansão na Amazônia: uma perspectiva geográfico-histórica
Design of an RF low-noise bandpass filter using active capacitance circuit (2005)

A novel RF active bandpass filter (BPF) is proposed and its noise performance is optimized by noise analysis. In the proposed design, a resonator consists of an active capacitance circuit together with a conventional inductor. The active capacitor is made of a field-effect transistor that exhibits negative resistance as well as capacitance. It can, therefore, compensate the loss of an inductor. Whereas the conventional active filters using negative resistance circuits usually have a high noise figure, the proposed active filter shows good noise property achieved by adopting a novel active capacitance circuit, which is proven by noise analysis and the experimental result. The measured second-order active BPF shows bandwidth of 95 MHz, 0.1-dB insertion loss, 0.3-dB ripple, and a noise figure of 2.4 dB at the 1.9-GHz band, which agrees well with the simulated results.