gebhart/patrepeval huggingface dataset:
A frequency domain method for blind source separation of convolutive audio mixtures (2005)

In this paper, we propose a new frequency domain approach to blind source separation (BSS) of audio signals mixed in a reverberant environment. We propose a joint diagonalization procedure on the cross power spectral density matrices of the signals at the output of the mixing system to identify the mixing system at each frequency bin up to a scale and permutation ambiguity. The frequency domain joint diagonalization is performed using a new and quickly converging algorithm which uses an alternating least-squares (ALS) optimization method. The inverse of the mixing system is then used to separate the sources. An efficient dyadic algorithm to resolve the frequency dependent permutation ambiguities that exploits the inherent nonstationarity of the sources is presented. The effect of the unknown scaling ambiguities is partially resolved using an initialization procedure for the ALS algorithm. The performance of the proposed algorithm is demonstrated by experiments conducted in real reverberant rooms. Performance comparisons are made with previous methods.
Propofol in Prehospital Treatment of Convulsive Status Epilepticus (1995)

We studied the safety and efficacy of intravenous propofol in the out-of-hospital treatment of convulsive status epilepticus (SE) in 8 patients (age 29-70 years), 4 of them with posttraumatic epilepsy. Four patients had no history of seizures. Convulsions ceased promptly after patients received a bolus of 100-200 mg propofol administered before hospital admission by staff of a mobile intensive care unit (ICU). The median duration of coma was 3 h 15 min (range 2-41 h), and the median duration of hospital treatment was 3 1/2 days (range 12 h to 23 days). Only 1 patient was admitted to the hospital's ICU. No adverse effects was observed except for a transient decrease in systolic blood pressure (SBP). Propofol may be a useful drug for the prehospital treatment of recurrent seizures not responding to intravenous diazepam (DZP).
Extending the use of biologics to mucous membranes by attachment of a binding domain (2023)

Biologics are almost exclusively administered systemically, but localized delivery is preferable as it minimizes off-target exposure and allows more aggressive treatments. Topical application of biologics to epithelia is generally ineffective because most are covered with fluids and biologics are washed out too quickly to have significant therapeutic effects. Here we explore the idea that attaching a binding domain can serve as an "anchor" to extend the residency time of biologics on wet epithelia, allowing their effective use even with infrequent applications. We use topical application to the ocular surface as a challenging test since foreign substances are washed out especially efficiently by tear flow and blinking. Our results demonstrate that conjugation of antibodies to wheat germ agglutinin, which binds GlcNAc and sialic acid that are ubiquitously present in tissues, increases their half-life 350-fold upon application to the ocular surface in a mouse model of dry eye, a common and onerous disease in humans. Importantly, antibodies to IL-17A, IL-23, and IL-1β conjugated to the agglutinin reduces manifestations of dry eye, even when applied just once daily. In contrast, unconjugated antibodies are ineffective. Attaching an anchor to biologics is a simple means to overcome washout and to extend their therapeutic use.
Application du calcul par intervalles aux systèmes à retards (2005)

Application du calcul par intervalles aux systemes a retards Massa Dao1 , Michael Di Loreto2 , Luc Jaulin 1 , Jean-Francois Lafay 2 et Jean Jacques Loiseau 2 1 LISA, CNRS-FRE-2656, Universite d’Angers, 62 Avenue Notre Dame du Lac, 49000 Angers, France dao@istia.univ-angers.fr, jaulin@univ-angers.fr 2 IRCCyN, CNRS-UMR-6597 1 rue de la Noe, BP 92101, 44321 Nantes cedex 03, France {michael.di-loreto, jean-francois.lafay, jean-jacques.loiseau}@irccyn.ec-nantes.fr Resume— Le but de ce papier est de montrer, a travers quelques exemples issus de la litterature, que le calcul par intervalles combine aux techniques de propagation de contraintes est un outil particulierement bien adapte a l’etude des systemes a retards. Mots-cles— Analyse par intervalles, inversion ensembliste, propagation de contraintes, systemes a retards, norme H∞, stabilite robuste, systemes a retards de type neutre, quasi- polynomes. I. Introduction On propose dans ce papier d’appliquer les methodes du calcul par intervalles ([2], [13], [14] et [9]) aux systemes a retards, afin de caracteriser leurs proprietes fondamen- tales, et d’analyser la sta
Modeling of Loading-path Dependent Martensitic Transformation in a Low-alloy TRIP Steel (2022)

The aim of this paper is to predict the deformation-induced martensitic transformation of the retained austenite in steels under various deformations, including loading-path changes, by using mesoscopic finite element analyses (FEAs). First, a TRIP steel was subjected to monotonic uniaxial tension and compression, as well as a couple of two-stage loadings to investigate the effect of loading direction and loading-path on transformation behavior experimentally. In monotonic loading, tension induced transformation at higher rate than compression did. Whereas, in two-stage loadings, the transformation progress was suspended immediately after the start of secondary loading. As the secondary tension proceeded, the transformation resumed and gradually accelerated toward the transformation rate for monotonic tension. These experimental results were analyzed by FEAs with a two-dimensional image of microstructure. The transformation rates under monotonic loading are well predicted by the simulation. It is also suggested that the difference in the transformation rate between tension and compression is mainly due to the volumetric expansion associated with martensitic transformation, and that the transformation behavior of the untransformed austenite is dominated by the distribution of the hard transformed martensite. In addition, the prediction of the transformation rate in secondary tension after pre-compression required the consideration of back stress in the austenite. The reproducibility of the transformation behavior just after the onset of secondary deformation was improved by the hypothesis that the equivalent value of back stress tensor at the transformation needs to exceed its maximum value in the past.
Saturated fat, vitamin C and smoking predict long-term population all-cause mortality rates in the Seven Countries Study (2000)

At the population level saturated fat, vitamin C and cigarette smoking are important determinants of all-cause mortality.
Simultaneously synthesized peptides on continuous cellulose membranes as substrates for protein kinases. (1996)

Sets of peptides with defined sequences, each on a separate spot, were synthesized simultaneously on continuous cellulose membranes (SPOTs membranes), which were originally designed for epitope studies. The applicability of the membrane-bound peptides as substrates for protein kinases was tested using protein kinase A, protein kinase C and casein kinases I and II as model enzymes. We found that the peptide-membrane complexes can serve as kinase substrates. Our results suggest that membrane-bound peptides offer a new potential for the investigation of substrate specificity of protein kinases. An advantage to this method is that there is no need for substrate identification and separation, which is required with high-volume random peptide libraries. Membrane-bound peptides may even form a basis for kinase assays with peptides lacking multiple basic amino acids, required for separation of the substrates in conventional assays. Problems connected with protein kinase substrate specificity can be investigated in any laboratory using the rapid and inexpensive SPOTs technique, as neither costly apparatus nor special experience in peptide synthesis is necessary.
Abundant Intracellular IgG in Enterocytes and Endoderm Lacking FcRn (2013)

FcRn, a non-classical MHCI molecule, transports IgG from mother to young and regulates the rate of IgG degradation throughout life. Brambell proposed a mechanism that unified these two functions, saying that IgG was pinocytosed nonspecifically by the cell into an FcRn-expressing endosome, where, at low pH, it bound to FcRn and was exocytosed. This theory was immediately challenged by claims that FcRn specificity for ligand could be conferred at the cell surface in neonatal jejunum. Assessing Brambell's hypothesis we found abundant nonspecifically endocytosed IgG present in the cytoplasm of FcRn(-/-) enterocytes. Further, IgG was present in the intercellular clefts and the cores of FcRn(+/+) but not FcRn(-/-) jejunum. FcRn specificity for ligand could be determined within the cell.
Sociodemographic and psychosocial factors associated with continuous subcutaneous insulin infusion in adolescents with type 1 diabetes (2009)

Adolescents currently prescribed CSII therapy evidenced key differences from their counterparts using multiple daily injections (MDI) in insurance status, diabetes management behavior, and family functioning related to diabetes. Efforts to understand the role of family factors in the maintenance of CSII therapy with clinical indicators of CSII use may inform treatment effectiveness.
Sports Camera Calibration via Synthetic Data (2019)

Calibrating sports cameras is important for autonomous broadcasting and sports analysis. Here we propose a highly automatic method for calibrating sports cameras from a single image using synthetic data. First, we develop a novel camera pose engine that generates camera poses by randomly sampling camera parameters. The camera pose engine has only three significant free parameters so that it can effectively generate diverse camera poses and corresponding edge (i.e. field marking) images. Then, we learn compact feature descriptors via a siamese network from paired edge images and build a feature-pose database. After that, we use a novel GAN (generative adversarial network) model to detect field markings in real images. Finally, we query an initial camera pose from the feature-pose database and refine camera poses using truncated distance images. We evaluate our method on both synthetic and real data. Our method not only demonstrates the robustness on the synthetic data but also achieves state-of-the-art accuracy on a standard soccer dataset and very high performance on a volleyball dataset.
Isolation Enhancement of a Very Compact UWB-MIMO Slot Antenna With Two Defected Ground Structures (2015)

A very compact ultrawideband (UWB) multiple-input multiple-output (MIMO) antenna with high isolation is presented in this letter. The proposed antenna, consisting of two UWB slot antennas, has a very compact size of 22 ×26 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> , which is smaller than most of UWB antennas only with single antenna element. A T-shaped slot is etched on the ground to improve the impedance matching characteristic in the low-frequency and reduce the mutual coupling for the frequencies ≥ 4 GHz. By etching a line slot to cancel out original coupling, isolation enhancement at the 3-4 GHz band is achieved. The antenna possesses a low mutual coupling of less than - 18 dB over the operating band from 3.1-10.6 GHz. The performance of this antenna both by simulation and by experiment indicates that the proposed antenna is a good candidate for UWB applications.
The determination of polyoxyethylene nonionic surfactants in water at the parts per million level (1964)

Abstract A method has been developed to determine the concn of polyoxyethylene nonionic surfactant (PNS) in the parts/million concn range in a water‐bacteria medium. The method has successfully determined the concn of PNS during the course of biodegradation studies using either activated sludge or river water as the bacterial source. The nonionic surfactant was removed from the water solution by continuous ether extraction. Detection and measurement of the PNS was accomplished using cobalt thiocyanate and measuring the absorbance of the blue cobalt‐PNS complex at 620 m.03 in a five‐cm absorption cell. Optimum extraction conditions required a neutral pH and a low ionic strength. The colorimetric step required that each molecule of PNS contain at least six ethylene oxide units for color development, and since the absorbance varies with the length of the polyoxyethylene chain, the method must be standardized using the particular compound under investigation.
Low Work Function between Erbium Silicide and n-type Silicon Controlled by Cap Film Stress (2012)

The electrical and physical properties of W capped ErSix on n-type Si(100), Si(111) and Si(551) surfaces are reported. The Schottky barrier heights (SBHs) are not determined by the growth of the ErSix crystal orientations, but are determined by the silicon surface orientations. And the SBHs are changed by the ratio of W capping layer thickness and ErSix thickness. These results are considered that the work function of ErSix can be controlled by the stress during the silicidation. These silicidation reactions are very important to develop the future high current drivability devices using any surface orientation.
Erratum for Pelegrin et al., “High-Risk International Clones of Carbapenem-Nonsusceptible Pseudomonas aeruginosa Endemic to Indonesian Intensive Care Units: Impact of a Multifaceted Infection Control Intervention Analyzed at the Genomic Level” (2020)

Volume 10, no. 6, e02384-19, 2019, https://doi.org/10.1128/mBio.02384-19. On PDF page 1, in the abstract, in the sentence “Four high-risk international CNPA clones (ST235, ST823, ST375, and ST446) dominated, but the distribution of these clones changed significantly after the intervention was implemented,” “ST375” within the parentheses should be “ST357.” This change does not change the conclusions of the paper.
Non-von-Kries 3-parameter color prediction (2003)

Chromatic adaptation transforms generally rely on a variant of the von Kries transformation-method to account for changes in the LMS cone signals that occur when changing from one illuminant to another. Von Kries adaptation also often referred to as the coefficient rule method or the diagonal transformation method-adjusts the 3 color channels by independent scale factors. Since there generally are only 3 known quantities available, namely the ratio of the cone signals of the two adapting illuminants, a crucial aspect of the von Kries method is that it requires only 3 parameters to be specified. A 9-parameter, 3x3 matrix transformation would be more accurate, but it is generally not possible to determine the extra parameters. This paper presents a novel method of predicting the effect a change of illumination has on the cone signals, while still relying on only 3 parameters. To begin, we create a large set of 3x3 matrices representing illuminant changes based on a sizable database of typical illuminant spectra and surface spectral reflectances. Representing these 3x3 matrices as points in a 9-dimensional space, we then apply principal components analysis to find a 3-dimensional basis which best approximates the original matrix space. To model an illumination change, a 3x3 matrix is constructed using a weighted combination of the 3 basis matrices. The relative weights can be calculated based on the 3 standard cone ratios obtained from the illuminant pair. Tests show that the new method yields better results than von Kries adaptation with or without sensor sharpening.
Predicting time series of individual trends with resolution adaptive ARIMA (2013)

It is important to analyze and predict the time series of traffic trends from the perspective of network operation and management, such as that in fine-grained traffic control, capacity dimensioning, and traffic engineering. However, it is difficult to accurately predict traffic trends because this strongly depends on the time, the type of content, and its popularity. We propose new methods of accurately predicting traffic trends in this paper. Our methods are based on a wavelet transform and the auto regressive integrated moving average (ARIMA) model. We first demonstrate that applying a wavelet transform can improve the accuracy of prediction compared to the original ARIMA model; however, it still has large error due to the fixed time granularity of each resolution. We therefore propose a resolution adaptive ARIMA (RA-ARIMA) model to improve accuracy by changing the time granularity according to the degree of resolution. We demonstrate that by applying it to the real monitored data in a major P2P file-sharing system the normalized mean squared error of RA-ARIMA can be reduced by more than 20% of that of Wavelet-ARIMA. Moreover, we also compared RA-ARIMA with other existing models to prove the accuracy of our proposed method.
Analyzing outliers cautiously (2002)

Outliers are difficult to handle because some of them can be measurement errors, while others may represent phenomena of interest, something "significant" from the viewpoint of the application domain. Statistical and computational methods have been proposed to detect outliers, but further analysis of outliers requires much relevant domain knowledge. In our previous work (1994), we suggested a knowledge-based method for distinguishing between the measurement errors and phenomena of interest by modeling "real measurements" - how measurements should be distributed in an application domain. In this paper, we make this distinction by modeling measurement errors instead. This is a cautious approach to outlier analysis, which has been successfully applied to a medical problem and may find interesting applications in other domains such as science, engineering, finance, and economics.
Design and Implementation of the Pervaho Middleware for Mobile Context-Aware Applications (2008)

Context-aware applications offer a great potential for the future of mobile computing. In order to be developed in an optimal way, such applications need appropriate middleware services. This paper introduces Pervaho, an integrated middleware aimed specifically for supporting the development and testing of mobile context-aware applications. To illustrate the use of Pervaho, we walk through the development of a concrete mobile context-aware application and show how it can be elegantly built on top of Pervaho's location-based publish/subscribe service. We also illustrate how a specialized mobility testing tool significantly simplifies the process of testing proximity-based semantics. We then present the implementation of Pervaho, which is based on a set of communication protocols geared at mesh networks. Finally, we provide a performance analysis of our implementation.
Net Normal-Dispersion Yb-Fiber Laser with Anomalous Dispersion Higher-Order-Mode Fiber (2011)

We present a mode-locked 24 MHz Yb-doped fiber oscillator with a higher-order mode fiber for dispersion compensation. The oscillator operates in the net normal dispersion regime and generates clean 6 nJ pulses that can be dechirped down to 150 fs.
Reduced Rift Valley Fever Virus Infection Rates in Mosquitoes Associated with Pledget Feedings (1988)

Infection rates were compared in Culex pipiens and Aedes taeniorhynchus after they fed on Rift Valley fever (RVF) viremic hamsters or ingested similar doses of RVF virus from blood-soaked pledgets. Infection rates were significantly lower for mosquitoes that ingested virus from a pledget than for those that ingested similar doses from viremic hamsters. The method used to prevent normal clot formation for the pledget feedings (i.e., defibrination by shaking with glass beads or addition of heparin) did not affect subsequent infection rates. Both inhibition of normal clot formation and freezing of virus after it had last been propagated were associated with significantly reduced infection rates with the pledget feedings. Laboratory studies using artificial feeding techniques may not give reliable estimates of the vector competence of mosquitoes for arboviruses.
Huge Photoresistance in Transparent and Conductive Indium Titanium Oxide Films Prepared by Electron Beam–Physical Vapor Deposition (2014)

Transparent and conductive indium titanium oxide (ITiO) films have been obtained by electron beam physical vapour deposition with Ti content from 5 at % up to 28 at %. X-ray absorption spectroscopy techniques have been used to identify the local environment of Ti ions. Even at the lowest concentrations Ti is not incorporated into the In2O3 structure but forms clusters of a Ti-In mixed oxide that present a distorted rutile TiO2 short-range order. The optical transmittance of the annealed samples reaches 95 % and no significant variation of the gap energy (around 3.7 eV) is observed with Ti content. The electronic conductivity under light irradiation is studied evidencing a huge photo-resistance in the samples with Ti content above 22 at % reaching more than two orders of magnitude for the 26 at % Ti under illumination with few μW/cm(2) at 365 nm. Hall and conductivity results are analyzed using a model that takes into account both electron and hole carriers as well as the conductivity enhancement by carrier photogeneration. The electron carrier density decreases with Ti content while its mobility increases up to values of 1000 cm(2)/(V s). Oxygen annealed ITiO films obtained by this technique with Ti content below 10 at % have properties adequate as transparent semiconductors and those with Ti content higher than 22 at % have exceptional photoresistive properties relevant for numerous applications.
Rapid Generation and Detection of Biomimetic Oxygen Concentration Gradients In Vitro (2017)

Hypoxic regions exist within most solid tumors and often lead to altered cellular metabolism, metastasis, and drug resistance. Reliable generation and detection of biomimetic gaseous gradients in vitro is challenging due to low spatiotemporal resolution and poor longevity of gradients utilizing microfluidic techniques. Here, we present a novel and simplistic approach for producing gradients of dissolved oxygen (DO) within a lab-on-a-chip platform. Linear and stable DO gradients with high spatial resolution are established by introducing pre-gassed media into the gradient generating network. An underlying platinum(ii) octaethlporphyrin ketone (PtOEPK) based sensor layer allows parallel detection of oxygen. A thin 3-sided glass coating on the inner channel walls prevents multi-directional diffusion of ambient oxygen across PDMS preserving the gradient resolution and stability. Viability analysis of normal mammary epithelial cells (MCF-12A) under oxygen gradients revealed 70% mortality after 6 hours of hypoxic exposure. Biological applicability of the platform was further validated by demonstrating increase in endoplasmic reticulum stress of MDA-MB-468 cells with time and with increasing oxygen tension. The unique ability to establish parallel or opposing gradients of gases and chemicals offers the potential for a wide range of applications in therapeutic development, and fundamental understanding of cellular behavior during hypoxia.
View Synthesis Using OpenGL for Multi-viewpoint 3D TV (2006)

In this paper, we propose an application of OpenGL functions for novel view synthesis from multi-view images and depth maps. While image based rendering has been meant to generate synthetic images by processing the camera view with a graphic engine, little has been known about how to apply the given images and depth information to the graphic engine and render the scene. This paper presents an efficient way of constructing a 3D space with camera parameters, reconstructing the 3D scene with color and depth images, and synthesizing virtual views in real-time as well as their depth images.