gebhart/patrepeval huggingface dataset:
The kinetic typography engine (2002)

Kinetic typography --- text that uses movement or other temporal change --- has recently emerged as a new form of communication. As we hope to illustrate in this paper, kinetic typography can be seen as bringing some of the expressive power of film --- such as its ability to convey emotion, portray compelling characters, and visually direct attention --- to the strong communicative properties of text. Although kinetic typography offers substantial promise for expressive communications, it has not been widely exploited outside a few limited application areas (most notably in TV advertising). One of the reasons for this has been the lack of tools directly supporting it, and the accompanying difficulty in creating dynamic text. This paper presents a first step in remedying this situation --- an extensible and robust system for animating text in a wide variety of forms. By supporting an appropriate set of carefully factored abstractions, this engine provides a relatively small set of components that can be plugged together to create a wide range of different expressions. It provides new techniques for automating effects used in traditional cartoon animation, and provides specific support for typographic manipulations.
Front Matter: Volume 7866 (2011)

A unique, consistent, permanent citation identifier (CID) number is assigned to each article at the time of
<title>Recent in-situ studies of the evolution of surfaces and interfaces of thin films by spectroscopic phase-modulated ellipsometry</title> (1993)

Application of spectroscopic phase modulated ellipsometry (PME) to study both ultrafast and slow processes of interaction of silane (SiH<SUB>4</SUB>) with thin film Pd, and to the investigation of the growth kinetics of a-Si:H films deposited by rf glow discharge under UV light irradiation are presented. As compared to other ellipsometric techniques like rotating analyzer ellipsometry (RAE), the phase modulation uses a high frequency of about 50 kHz provided by a photoelastic modulator. Thus, PME allows one to reach 1 - 5 ms time resolution which permits faster real-time measurements than RAE. This remarkable feature of PME makes it particularly suitable for in-situ applications. Changes of optical properties of Pd thin films exposed to SiH<SUB>4</SUB> at different fluxes are monitored by in situ single wavelength ellipsometry in the case of high fluxes which lead to ultrafast process and by in situ spectroscopic ellipsometry at small fluxes and slow kinetics. The study reveals a complicated character of the process which depends on initial flux of silane and leads to formation of Pd disilicide, Pd hydride, and an intrinsic porosity. A qualitative model of the process is proposed.
The TGN/EE SNARE protein SYP61 and the ubiquitin ligase ATL31 cooperatively regulate plant responses to carbon/nitrogen conditions in Arabidopsis (2022)

Ubiquitination is a post-translational modification involving the reversible attachment of the small protein ubiquitin to a target protein. Ubiquitination is involved in numerous cellular processes, including the membrane trafficking of cargo proteins. However, the ubiquitination of the trafficking machinery components and their involvement in environmental responses are not well understood. Here, we report that the Arabidopsis thaliana trans-Golgi network/early endosome localized SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) protein SYP61 interacts with the transmembrane ubiquitin ligase ATL31, a key regulator of resistance to disrupted carbon (C)/nitrogen/(N)-nutrient conditions. SYP61 is a key component of membrane trafficking in Arabidopsis. The subcellular localization of ATL31 was disrupted in knockdown mutants of SYP61, and the insensitivity of ATL31-overexpressing plants to high C/low N-stress was repressed in these mutants, suggesting that SYP61 and ATL31 cooperatively function in plant responses to nutrient stress. SYP61 is ubiquitinated in plants, and its ubiquitination level is upregulated under low C/high N-nutrient conditions. These findings provide important insights into the ubiquitin signaling and membrane trafficking machinery in plants.
Conjugation of quantum dots on carbon nanotubes for medical diagnosis and treatment (2013)

Cancer is one of the leading causes of death worldwide and early detection provides the best possible prognosis for cancer patients. Nanotechnology is the branch of engineering that deals with the manipulation of individual atoms and molecules. This area of science has the potential to help identify cancerous cells and to destroy them by various methods such as drug delivery or thermal treatment of cancer. Carbon nanotubes (CNT) and quantum dots (QDs) are the two nanoparticles, which have received considerable interest in view of their application for diagnosis and treatment of cancer. Fluorescent nanoparticles known as QDs are gaining momentum as imaging molecules with life science and clinical applications. Clinically they can be used for localization of cancer cells due to their nano size and ability to penetrate individual cancer cells and high-resolution imaging derived from their narrow emission bands compared with organic dyes. CNTs are of interest to the medical community due to their unique properties such as the ability to deliver drugs to a site of action or convert optical energy into thermal energy. By attaching antibodies that bind specifically to tumor cells, CNTs can navigate to malignant tumors. Once at the tumor site, the CNTs enter into the cancer cells by penetration or endocytosis, allowing drug release, and resulting in specific cancer cell death. Alternatively, CNTs can be exposed to near-infrared light in order to thermally destroy the cancer cells. The amphiphilic nature of CNTs allows them to penetrate the cell membrane and their large surface area (in the order of 2600 m(2)/g) allows drugs to be loaded into the tube and released once inside the cancer cell. Many research laboratories, including our own, are investigating the conjugation of QDs to CNTs to allow localization of the cancer cells in the patient, by imaging with QDs, and subsequent cell killing, via drug release or thermal treatment. This is an area of huge interest and future research and therapy will focus on the multimodality of nanoparticles. In this review, we seek to explore the biomedical applications of QDs conjugated to CNTs, with a particular emphasis on their use as therapeutic platforms in oncology.
Integrating Patient Preference into Treatment Decisions for Men with Prostate Cancer at the Point of Care (2016)

Implementation of this web based intervention was associated with decreased decisional conflict and enhanced elements of shared decision making.
The photooxidation of nylon 6 and 66 (1962)

Abstract The chemical changes occurring in nylon (6 and 66) on irradiation have been studied. The results confirm earlier work on model systems which showed the main attack to be between the‐NH‐group of the amide bond and the adjacent‐CH 2 ‐group. However, a number of products were found that indicate a more complicated course of the reaction. The similarily of photooxidation and thermal degradation 8 is pointed out.
Considerations for Polarimetric Upgrades to Operational WSR-88D Radars (2000)

This paper reports on the steps taken by the National Severe Storms Laboratory (NSSL) to 1) develop open system hardware to facilitate upgrades to the WSR-88D (NEXRAD) radar and 2) improve identification of the type of precipitation and its quantitative measure. An engineering evaluation is made to determine if the WSR-88D antenna assembly with minimum modification could be used in a polarimetric mode. The polarimetric characteristics and radiation patterns of a research WSR-88D are briefly discussed. Considerations for the choice of polarimetric basis and design options are described. A polarimetric scheme employing simultaneous transmission of horizontally (H) and vertically (V) polarized waves is suggested for the WSR-88D, which eliminates an expensive, high-power switch. A theoretical evaluation is performed to determine the effects that feed alignment, drop canting, and backscatter depolarization have on the measurements of polarimetric parameters made with simultaneous transmission and reception of H and V signals. Experiments with the Colorado State University–Universities of Chicago and Illinois radar are performed to compare polarimetric variables obtained with alternate and simultaneous transmissions of H, V waves. Both simultaneous reception in two receivers and alternate reception in one receiver have been used.
Monte Carlo Simulation of the Grafting of Maleic Anhydride onto Polypropylene at Higher Temperature (2003)

The graft of maleic anhydride (MAH) onto isotactic polypropylene (iPP) initiated by dicumyl peroxide (DCP) at 190 °C was studied by means of the Monte Carlo method. The ceiling temperature theory, i.e., no possibility for the homopolymerization of MAH to occur at higher temperatures, was used in this study. The simulation results show that most MAH monomers were grafted onto the radical chain ends arising from β scission at a lower MAH concentration, whereas the amount of MAH monomers attached to the tertiary carbons was much larger than that grafted onto the radical chain ends at a higher MAH concentration for various DCP concentrations. This conclusion gives a good interpretation for the disagreement on the grafting sites along a PP chain. Moreover, it was found that the grafting degree increased considerably up to a peak value; thereafter, it decreased continuously with increasing MAH concentration. The peak shifted in the lower MAH concentration direction and became lower and lower with increasing DCP concentration. When the DCP concentration was below 0.1 wt %, the peak was hardly observed. Those results are in good agreement with the experiments. On the other hand, the simulation results show that the average grafting number of MAH monomers on per PP chain maintained almost a linear relationship with chain length for various DCP and MAH concentrations. The quantitative relationship among PP molecular weight, DCP, and MAH concentrations was also obtained in this study.
Multipoint Synchronization for Fog-Controlled Internet of Things (2019)

This paper presents a fog-resident controller architecture for synchronizing the operations of large collections of Internet of Things (IoT), such as drones, Internet of Vehicles, etc. Synchronization in IoT is grouped into different classes, use cases identified and multipoint synchronous scheduling algorithms are developed to schedule tasks with varying timing requirements; strict (synchronous) and relaxed (asynchronous and local) onto a bunch of worker nodes that are coordinated by a fog resident controller in the presence of disconnections and worker failures. The algorithms use time-based or component-based redundancy to cope with failures and embed a publish-subscribe message update scheme to reduce the message overhead at the controller as the number of workers increase. The performance of the algorithms are evaluated using trace-driven experiments and practicability is shown by implementing the time-based redundancy synchronous scheduling algorithm in JAMScript-a polyglot programming platform for Cloud of Things and report initial findings.
Histological recurrence of autoimmune liver diseases after living‐donor liver transplantation (2007)

Blood-relative donors may be associated with susceptibility to recurrent autoimmune diseases. Recurrence of PSC, but not PBC, adversely affected the outcome of LDLT. Caution should be taken as blood-relative donors can be at risk of autoimmune liver diseases.
Novel hybrid epoxy silicone materials as efficient anticorrosive coatings for mild steel (2015)

Novel hybrid organic–inorganic coatings were successfully prepared, coated on mild steel, and subjected to different spectral, electrochemical and morphological characterizations.
CTLA-4: Negative Regulator of the Immune Response and a Target for Cancer Therapy (2008)

A novel approach for cancer immunotherapy is to augment T-cell-mediated immunity by blocking inhibitory signals that suppress T-cell function. Cytotoxic T-lymphocyte antigen-4 (CTLA-4) is a key negative regulator of T-cell activation. CTLA-4 blockade using anti-CTLA-4 monoclonal antibodies (mAbs) potentiates the T-cell response against tumors, and preliminary data on these agents demonstrate good efficacy and tolerability in the treatment of patients with metastatic melanoma and other cancers. This paper will review data from studies with anti-CTLA-4 mAbs to date, discuss some of the key clinical considerations emerging from early clinical trials with this therapeutic strategy, and provide an overview of ongoing and planned clinical trials for anti-CTLA-4 mAb therapy in metastatic melanoma and other cancers.
Teaching subjects to pupils with profound and multiple learning difficulties (1999)

Nicola Grove, who lectures in speech and language therapy and works in a school for pupils with severe and profound learning difficulties, and Nick Peacey, Director of the Special Educational Needs Joint Initiative for Training (SENJIT) at the Institute of Education, discuss the development of a framework for teaching National Curriculum subjects to pupils with profound learning difficulties through discussion with mainstream specialists.
Practical multigram syntheses of benzocyclobutenediones (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPractical multigram syntheses of benzocyclobutenedionesMichael S. South and Lanny S. LiebeskindCite this: J. Org. Chem. 1982, 47, 20, 3815–3821Publication Date (Print):September 1, 1982Publication History Published online1 May 2002Published inissue 1 September 1982https://doi.org/10.1021/jo00141a002RIGHTS & PERMISSIONSArticle Views1412Altmetric-Citations47LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (1015 KB) Get e-Alerts Get e-Alerts
Alendronate Treatment in Women With Normal to Severely Impaired Renal Function: An Analysis of the Fracture Intervention Trial (2007)

Alendronate is safe and effective at increasing BMD and decreasing fractures among this group of women with reduced renal function.
A Fiber-Optic System for the Quasi-Distributed Detection of Liquids (2015)

This letter presents a multiplexed fiber-optic sensor array suitable for detection of liquid intrusions, spills, and leaks. The proposed detection systems is based on active heating and observation of temperature changes in short sections of optically absorbing (vanadium-doped) optical fibers that were interconnected into a sensing array by a standard single-mode optical fiber. The heating of the vanadium-doped fiber sections was achieved by application of a common 980-nm pump laser source. The associated signal processing and integration utilizes a simple, custom-designed optical time domain reflectometry that relies on only a few low-cost standard telecom components.
A pilot study of buprenorphine—naloxone combination tablet (Suboxone®) in treatment of opioid dependence (2004)

In Australia, maintenance treatment for opioid dependence involves supervised daily administration of a dose of methadone or buprenorphine. A sublingual tablet combining buprenorphine and naloxone in a 4:1 ratio (Suboxone) has been developed, designed to deter diversion and intravenous misuse, and may be suitable for unsupervised administration. The aim of this study was to investigate the tolerability of Suboxone, and investigate whether unsupervised administration can be effective in stabilized patients. Employed patients on buprenorphine maintenance, who had ceased heroin use, were switched to Suboxone and provided with weekly supplies of medication to take without supervised administration. Subjects were monitored closely with weekly clinical reviews, and research interviews at baseline, 3 and 6 months. Only 11% of people receiving buprenorphine met eligibility criteria. Seventeen subjects were recruited. Fifteen were retained for the full 6 months. No subject appeared destabilized by unsupervised dosing. Suboxone was well tolerated. The current trial demonstrated that unsupervised administration with regular clinical monitoring can be effective in selected patients. However, using access to unsupervised dosing to promote abstinence from heroin probably limits the potential benefits of unsupervised administration to a very small proportion of patients.
Pyruvate Decarboxylase (1971)

Pyruvate decarboxylase, isolated from active dry bakers' yeast, dissociates into subunits of one-half the molecular weight at alkaline pH. This has been determined by chromatography on Sephadex G-200 over the pH range 6.5 to 8.0. The conditions at which protein dissociation is observed are the same as the conditions at which the cofactors thiamine pyrophosphate and Mg2+ are released and can be separated from the protein. When the holoenzyme is reconstituted in the presence of thiamine-PP and Mg2+ the active enzyme is a dimer of the same molecular weight as the original native enzyme. When the apoenzyme, subjected to the reconstitution procedure in the absence of thiamine-PP and Mg2+, is chromatographed on Sephadex G-200 at pH 6.5 the protein is eluted at an intermediate position, suggesting a monomer-dimer equilibrium which favors the monomer. It appears that thiamine-PP in addition to its catalytic role also functions in the formation of a stable dimer which is the active holoenzyme. The presence of a subunit association step in the reconstitution process which requires thiamine-PP and Mg2+ identifies a site which may be related to the unusual requirement for excess thiamine-PP in the reconstitution process. A method for selectively staining pyruvate decarboxylase on disc electrophoresis gels with a fuchsin staining reagent is described.
A facile preparation strategy of polycaprolactone (PCL)-based biodegradable polyurethane elastomer with a highly efficient shape memory effect (2019)

A polycaprolactone (PCL)-based biodegradable polyurethane elastomer with a highly efficient shape memory effect.
Design of Highly Linear, 1GHz 8-bit Digitally Controlled Ring Oscillator with Wide Tuning Range in 0.18um CMOS Process (2008)

This paper presents a simple architecture for 8-bit digital controlled oscillator (DCO) on 3-stages ring topology in TSMC 0.18 um CMOS technology. A new schematic of tristate inverter is also proposed. The proposed tristate inverter has higher switching speed and low power consumption as compared to conventional one. The control digit changes the driving current that provides large tuning range from 316 MHz to 1165 MHz with very good linearity. The output voltage swing is always greater than 1.6 V while the supply voltage is 1.8 V. The proposed DCO has simulated phase noise of -114 dBc/Hz @1 MHz and 23.2 mW power consumption at 1.0 GHz central frequency.
Mature MiR-17-5p and passenger miR-17-3p induce hepatocellular carcinoma by targeting PTEN, GalNT7, and vimentin in different signal pathways (2013)

To study the physiological role of a single microRNA (miRNA), we generated transgenic mice expressing the miRNA precursor miR-17 and found that the mature miR-17-5p and the passenger strand miR-17-3p were abundantly expressed. We showed that mature miR-17-5p and passenger strand miR-17-3p could synergistically induce the development of hepatocellular carcinoma. The mature miR-17-5p exerted this function by repressing the expression of PTEN. In contrast, the passenger strand miR-17-3p repressed expression of vimentin, an intermediate filament with the ability to modulate metabolism, and GalNT7, an enzyme that regulates metabolism of liver toxin galactosamine. Hepatocellular carcinoma cells, HepG2, transfected with miR-17 formed larger tumors with more blood vessels and less tumor cell death than mock-treated cells. Expression of miR-17 precursor modulated HepG2 proliferation, migration, survival, morphogenesis and colony formation and inhibited endothelial tube formation. Silencing of PTEN, vimentin or GalNT7 with their respective siRNAs enhanced proliferation and migration. Re-expressing these molecules reversed their roles in proliferation, migration and tumorigenesis. Further experiments indicated that these three molecules do not interact with each other, but appear to function in different signaling pathways. Our results demonstrated that a mature miRNA can function synergistically with its passenger strand leading to the same phenotype but by regulating different targets located in different signaling pathways. We anticipate that our assay will serve as a helpful model for studying miRNA regulation.
Synthesis of the nanostructured WO3 via anodization at elevated temperature for H2 sensing applications (2011)

Nanosturctured WO3 films were synthesized via anodization at elevated temperature. Nitric acid (HNO3) and sulfuric acid (H2SO4) were employed for the first time. Different nanostructured morphologies were observed. The novel conductometric H2 gas sensor has been developed based on these WO3 films. The sensor with anodized WO3 film in HNO3 exhibited high sensitivity towards H2 as low as 0.06% at relatively low operating temperature (120 °C).
Fibrosing colonopathy in an adult owing to over use of pancreatic enzyme supplements: Figure 1 (2000)

A woman, then in her late 20s, underwent a cholecystectomy in 1962 for gallstone disease and subsequent common bile duct stones were managed endoscopically. However, because of unrelenting pain, a pylorus preserving pancreaticoduodenectomy was done in 1990 and in the following years the patient took large amounts of pancreatic enzyme supplements. She developed large bowel obstruction in 1997 and a right hemicolectomy was undertaken. Histology confirmed fibrosing colonopathy of the ascending colon and caecum. Her pancreatic enzyme dose was reduced and her subsequent course has been uncomplicated.
The influence of particle size on the physical behaviour of colloidal systems (1940)

H. C. Hamaker, Trans. Faraday Soc., 1940, 35, 186 DOI: 10.1039/TF9403500186
The piezoelectric effect in Na0.5Bi0.5TiO3 ceramics (2002)

Piezoelectric properties of Na0.5Bi0.5TiO3 ceramics have been investigated over a broad temperature range using a resonance technique. The thermal behaviours of the piezoelectric tensor coefficients d31, d33 and d15 confirm that there is a distinct phase transformation at 200 °C. For the first time it has been found that a piezoelectric signal connected with the tensor component d33 is observed up to 280 °C. This corresponds to earlier neutron and x-ray diffraction data on the point of transition from rhombohedral to tetragonal symmetry.
Changes in refractive index of fluoride glass fibers during fiber fabrication processes (1990)

Refractive indices of fluoride glass fibers were measured for the first time and a remarkable decrease in the refractive index during fiber fabrication processes has been observed. This decrease is most likely due to the change in the glass structure during fiber drawing and due to the stress induced during preform fabrication processes.