gebhart/patrepeval huggingface dataset:
Mining interprocedural, data-oriented usage patterns in JavaScript web applications (2014)

A frequently occurring usage of program elements in a programming language and software libraries is called a usage pattern. In JavaScript (JS) Web applications, JS usage patterns in their source code have special characteristics that pose challenges in pattern mining. They involve nested data objects with no corresponding names or types. JS functions can be also used as data objects. JS usages are often cross-language, inter-procedural, and involve control and data flow dependencies among JS program entities and data objects whose data types are revealed only at run time due to dynamic typing in JS. This paper presents JSModel, a novel graph-based representation for JS usages, and JSMiner, a scalable approach to mine inter-procedural, data-oriented JS usage patterns. Our empirical evaluation on several Web programs shows that JSMiner efficiently detects more JS patterns with higher accuracy than a state-of-the-art approach. We conducted experiments to show JSModel's usefulness in two applications: detecting anti-patterns (buggy patterns) and documenting JS APIs via pattern skeletons. Our controlled experiment shows that the mined patterns are useful as JS documentation and code templates.
Cooperative Ligand Effects in Phase‐Switching Homogeneous Catalysts (2012)

Es gehören zwei dazu: Xantphos-Liganden mit Amidatgruppen ergeben bei der Rh-katalysierten Hydroformylierung von 1-Octen selektiv lineare Produkte gegenüber verzweigten. Allerdings geht der Katalysator nur in Gegenwart von Amidin-substituiertem Triphenylphosphan einen CO2-vermittelten Phasentransfer ein (siehe Schema). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Hypertension guidelines: Beware diuretics in elderly patients (1993)

Hypertension guidelines 1B blockers no good for smokers EDITOR,-Though I welcome the British Hyper- tension Society's management guidelines in essential hypertension, I am dismayed that there is no mention of the importance of smoking in the choice of first line antihypertensive drug.'The Medical Research Council's trials in both young and older adults clearly showed that smokers do not benefit from , blockers.23Moreover, the trial in older adults indicated that the excess non- cardiovascular mortality in the treated groups was largely attributable to cancers in the ,B blocker group.3I am not aware of any study of hypertension which has refuted these grave doubts about (B blockade and believe that the rationale for its current use, not restricted to non-smokers, is merely that it lowers blood pressure despite the evidence that smokers would be at least as healthy without the (3blockers and possibly healthier.
Ventricular arrhythmias in patients with prior aortic valve intervention: Characteristics, ablation and outcomes (2023)

CA of VAs can be performed safely and effectively in patients with prior AVI.
Origins of Structural Hole Traps in Hydrogenated Amorphous Silicon (2013)

The inherently disordered nature of hydrogenated amorphous silicon (a-Si:H) obscures the influence of atomic features on the trapping of holes. To address this, we have created a set of over two thousand ab initio structures of a-Si:H and explored the influence of geometric factors on the occurrence of deep hole traps using density-functional theory. Statistical analysis of the relative contribution of various structures to the trap distribution shows that floating bonds and ionization-induced displacements correlate most strongly with hole traps in our ensemble.
Perturbational Gene-Expression Signatures for Combinatorial Drug Discovery (2019)

Cancer is a complex disease that relies on both oncogenic mutations and non-mutated genes for survival, and therefore coined as oncogene and non-oncogene addictions. The need for more effective combination therapies to overcome drug resistance in oncology has been increasingly recognized, but the identification of potentially synergistic drugs at scale remains challenging. Here we propose a gene-expression-based approach, which uses the recurrent perturbation-transcript regulatory relationships inferred from a large compendium of chemical and genetic perturbation experiments across multiple cell lines, to engender a testable hypothesis for combination therapies. These transcript-level recurrences were distinct from known compound-protein target counterparts, were reproducible in external datasets, and correlated with small-molecule sensitivity. We applied these recurrent relationships to predict synergistic drug pairs for cancer and experimentally confirmed two unexpected drug combinations in vitro. Our results corroborate a gene-expression-based strategy for combinatorial drug screening as a way to target non-mutated genes in complex diseases.
Complete Genome Sequences of Four Salmonella enterica Strains (Including Those of Serotypes Montevideo, Mbandaka, and Lubbock) Isolated from Peripheral Lymph Nodes of Healthy Cattle (2019)

Salmonella enterica serotype Lubbock emerged most likely from a Salmonella enterica serotype Mbandaka ancestor that acquired by recombination the <i>fliC</i> operon from Salmonella enterica serotype Montevideo. Here, we report the complete genome sequence of two <i>S.</i> Lubbock, one <i>S.</i> Montevideo, and one <i>S.</i> Mbandaka strain isolated from bovine lymph nodes.
Sodium beacon tip--tilt determination with Rayleigh-aided auxiliary telescope technique (1998)

The usefulness of tracking the Rayleigh portion of a mesospheric sodium laser guide star as reference for absolute tip—tilt recovery in the frame of the auxiliary telescopes technique is shown. This approach leads to the reduction of the ground occupation needed to attain a given sky coverage by more than one order of magnitude. Speed, tracking precision, and the number of auxiliary telescopes are also reduced, making this new approach a more attractive one. The use of a low-altitude Rayleigh spot reinforces the fundamental limitations affecting this and other techniques, thus degrading significantly the quality of the recovered tip—tilt. However, it is shown that, provided adequate care is taken in the collection and treatment of data, an interesting tilt signal can still be retrieved.
A line fiducial method for geometric calibration of cone-beam CT systems with diverse scan trajectories (2017)

Modern cone-beam CT systems, especially C-arms, are capable of diverse source-detector orbits. However, geometric calibration of these systems using conventional configurations of spherical fiducials (BBs) may be challenged for novel source-detector orbits and system geometries. In part, this is because the BB configurations are designed with careful forethought regarding the intended orbit so that BB marker projections do not overlap in projection views. Examples include helical arrangements of BBs (Rougee et al 1993 Proc. SPIE 1897 161-9) such that markers do not overlap in projections acquired from a circular orbit and circular arrangements of BBs (Cho et al 2005 Med. Phys. 32 968-83). As a more general alternative, this work proposes a calibration method based on an array of line-shaped, radio-opaque wire segments. With this method, geometric parameter estimation is accomplished by relating the 3D line equations representing the wires to the 2D line equations of their projections. The use of line fiducials simplifies many challenges with fiducial recognition and extraction in an orbit-independent manner. For example, their projections can overlap only mildly, for any gantry pose, as long as the wires are mutually non-coplanar in 3D. The method was tested in application to circular and non-circular trajectories in simulation and in real orbits executed using a mobile C-arm prototype for cone-beam CT. Results indicated high calibration accuracy, as measured by forward and backprojection/triangulation error metrics. Triangulation errors on the order of microns and backprojected ray deviations uniformly less than 0.2 mm were observed in both real and simulated orbits. Mean forward projection errors less than 0.1 mm were observed in a comprehensive sweep of different C-arm gantry angulations. Finally, successful integration of the method into a CT imaging chain was demonstrated in head phantom scans.
MO047STABLE EGFR IN PATIENTS WITH PRIMARY HYPEROXALURIA TYPE 1 TREATED WITH LUMASIRAN, REGARDLESS OF KIDNEY FUNCTION AT START OF TREATMENT (2021)

Abstract Background and Aims Primary hyperoxaluria type 1 (PH1) is a rare genetic disorder characterized by hepatic oxalate overproduction. Excess oxalate is excreted by the kidneys, leading to recurrent kidney stones, nephrocalcinosis, and progressive kidney disease. Patients with PH1 generally experience a slow decline in kidney function over time that can be punctuated by abrupt worsening precipitated by infection, obstructing stones, or dehydration. Approximately half of patients with PH1 progress to kidney failure by early adulthood, and nearly all by 60 years of age. Lumasiran is an RNAi therapeutic indicated for the treatment of PH1 in all age groups. In clinical trials, treatment with lumasiran resulted in substantial reductions in urinary and plasma oxalate in pediatric and adult patients, with an acceptable safety profile. This analysis evaluates the change in kidney function of patients with PH1 with an eGFR of ≥30 mL/min/1.73m2 enrolled in clinical trials of lumasiran. Method We analyzed kidney function from 75 patients with PH1, age ≥12 months old, eGFR ≥30 mL/min/1.73m2, enrolled in 3 clinical trials of lumasiran (Phase 2 open-label extension, and Phase 3 ILLUMINATE-A and ILLUMINATE-B). In these trials, eGFR was calculated with the Modification of Diet in Renal Disease (MDRD) Study equation in adults or the bedside Schwartz equation in children. The effect of lumasiran on eGFR was assessed by baseline eGFR subgroup: ≥90, &amp;lt;90, 60 to &amp;lt;90, 45 to &amp;lt;60, and 30 to &amp;lt;45 mL/min/1.73m2. Results Of 75 patients available for analysis, 46 were treated with lumasiran from the start of the study through the Month 12 visit. eGFR remained stable in all eGFR subgroups. Patients with eGFR ≥90 mL/min/1.73m2 at baseline (N=16) demonstrated fluctuations in mean values by timepoint, with a mean change (95% CI) from baseline of -1 (-8, 6) mL/min/1.73m2 at Month 12. In patients with eGFR &amp;lt;90 mL/min/1.73m2 (N=30), no change in mean eGFR from baseline was observed at Month 12; the mean change (95% CI) was 0 (-3, 3). When evaluating subgroups with impaired kidney function, variations in the mean change were observed at Month 12 due to small sample sizes. For patients with eGFR 60 to &amp;lt;90 mL/min/1.73m2 (N=22), the mean change (95% CI) was -2 (-5, 1). For patients with eGFR 45 to &amp;lt;60 mL/min/1.73m2 (N=5), the mean change (95% CI) was 3 (-8, 14). For patients with eGFR 30 to &amp;lt;45 mL/min/1.73m2 (N=3), the mean change (95% CI) was 9 (7, 11). Conclusion Patients with PH1 had stable kidney function over time with lumasiran treatment, regardless of kidney function at baseline. Given the progressive kidney function decline that is characteristic of PH1, the eGFR stability observed during 12 months of treatment with lumasiran is encouraging. Kidney function will continue to be monitored for the duration of the lumasiran clinical trials.
PKM (2008)

This paper presents PKM - a web-based tool for knowledge management in an environment centered on the concept of the experience factory. The tool focuses on managing explicit knowledge, most of which is collected in an automated way using non-invasive plug-ins and probes. It provides customizable metric views, metric interpretation and abstraction capabilities, helps in extraction and evaluation of metric progress models.
Dispersion Measurement of Infrared Specialty Fibers (2012)

We demonstrate broadband (&gt;250nm) dispersion measurements and theoretical calculations in a set of short-length specialty fibers in the 2.16-2.41µm wavelength range for femtosecond mid-IR applications using an ultrabroadband Cr:ZnS laser as a source.
Excitonic interaction amongst InP/ZnS salt pellets (2017)

FRET enabled Cd-free quantum dot pellets for white light generation has been demonstrated.
Photopolymerizable nanocomposite photonic materials and their holographic applications in light and neutron optics (2016)

We present an overview of recent investigations of photopolymerizable nanocomposite photonic materials in which, thanks to their high degree of material selectivity, recorded volume gratings possess high refractive index modulation amplitude and high mechanical/thermal stability at the same time, providing versatile applications in light and neutron optics. We discuss the mechanism of grating formation in holographically exposed nanocomposite materials, based on a model of the photopolymerization-driven mutual diffusion of monomer and nanoparticles. Experimental inspection of the recorded grating's morphology by various physicochemical and optical methods is described. We then outline the holographic recording properties of volume gratings recorded in photopolymerizable nanocomposite materials consisting of inorganic/organic nanoparticles and monomers having various photopolymerization mechanisms. Finally, we show two examples of our holographic applications, holographic digital data storage and slow-neutron beam control.
Free-space optical polarization demultiplexing and multiplexing by means of conical refraction (2012)

Polarization demultiplexing and multiplexing by means of conical refraction is proposed to increase the channel capacity for free-space optical communication applications. The proposed technique is based on the forward-backward optical transform occurring when a light beam propagates consecutively along the optic axes of two identical biaxial crystals with opposite orientations of their conical refraction characteristic vectors. We present an experimental proof of usefulness of the conical refraction demultiplexing and multiplexing technique by increasing in one order of magnitude the channel capacity at optical frequencies in a propagation distance of 4 m.
Abstract 16816: Are the Triggers From the Left Atrial Appendage Critical in Determining the Long-Term Outcome of Catheter Ablation in Patients With Long-Standing Persistent Atrial Fibrillation? Results From 5-Year Follow-Up (2017)

Background: In recent years catheter ablation techniques and strategies have evolved substantially. Despite all the efforts, post-ablation recurrence still has been a key issue and targeting non-PV...
Trapping light into high orbital momentum modes of fiber tapers (2015)

A tapered cylindrical dielectric optical waveguide acts as a high quality factor white-light cavity providing high field concentration as well as long optical group delay. It is possible to optimize shape of a lossless taper to suppress reflection of the input light and to achieve infinitely high field concentration. These tapers can be used in sensing and optoelectronics applications instead of conventional microcavities.
Neoadjuvant Chemotherapy for Breast Cancer Increases the Rate of Breast Conservation: Results from the National Cancer Database (2015)

Neoadjuvant chemotherapy increases breast preservation for patients with breast tumor size larger than 3 cm.
Sponge-Derived 24-Homoscalaranes as Potent Anti-Inflammatory Agents (2020)

Scalarane-type sesterterpenoids are known for their therapeutic potential in cancer treatments. However, the anti-inflammatory properties of this class of metabolites remain elusive. Our current work aimed to investigate the anti-inflammatory scalaranes from marine sponge <i>Lendenfeldia</i> sp., resulting in the isolation of six new 24-homoscalaranes, lendenfeldaranes E-J (<b>1</b>-<b>6</b>). The structures of the new metabolites were determined by extensive spectroscopic analyses, and the absolute configuration of <b>1</b> was established by electronic circular dichroism (ECD) calculations. Compounds <b>2</b> and <b>3</b> were discovered to individually reduce the generation of superoxide anions, and compound <b>1</b> displayed an inhibitor effect on the release of elastase. These three compounds were proven to be the first anti-neutrophilic scalaranes.
Spatial distribution of the phases in water-in-oil emulsions. Open and closed microcellular foams from cross-linked polystyrene (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSpatial distribution of the phases in water-in-oil emulsions. Open and closed microcellular foams from cross-linked polystyreneJoel M. Williams and Debra A. WrobleskiCite this: Langmuir 1988, 4, 3, 656–662Publication Date (Print):May 1, 1988Publication History Published online1 May 2002Published inissue 1 May 1988https://pubs.acs.org/doi/10.1021/la00081a027https://doi.org/10.1021/la00081a027research-articleACS PublicationsRequest reuse permissionsArticle Views1549Altmetric-Citations246LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Reduction of Aromatic Hydrocarbons by a New Reducing System: Calcium Metal in Amines (1983)

Abstract Recently we reported that calcium in an equal volume mixture of methyl ami ne and ethyl enedi ami ne reduces aromatic hydrocarbons to monoal kenes and that for certain substrates unconjugated cyclic dienes are the preferred product.
Single acquisition water‐fat separation: Feasibility study for dynamic imaging (2005)

Water-fat separation can be challenging in the presence of field inhomogeneities. Three-point (3-pt) water-fat separation methods achieve robust performance by measuring and compensating for field inhomogeneities; however, they triple the scan time. The "1+-pt" water-fat separation method proposed in this article for dynamic or repetitive imaging situations combines 3-pt methods' ability to correct for field inhomogeneities with the scan efficiency of a single acquisition method to achieve high temporal and spatial resolutions and robust water-fat separation. Single-echo data are collected with water and fat at a relative phase shift of an odd multiple of pi/2. To correct for undesired phase modulation, phase maps are estimated from a 3-pt calibration scan acquired prior to dynamic imaging. The phase maps are assumed to be slowly varying in time, so they may be used for correcting the phase of the subsequent single-echo signals at the same imaging location. Noise performance was investigated and shown to be equivalent to a single excitation acquisition. The 1+-pt method can also be used in conjunction with parallel imaging. In this situation, the calibration scans required by both methods can be integrated into a shared calibration scan. Promising results were obtained in breast, abdominal, and cardiac imaging applications.
3D Digital Documentation of Historic Launch Complex Structures at Cape Canaveral Air Force Station (CCAFS): A Workflow Methodology for DoD Cultural Resources (2015)

This project was undertaken to provide baseline terrestrial laser scanning (TLS) survey and spatial recordation for six historic launch complexes. Select structures were chosen for 3D laser scan survey, and these data were brought together with aerial Light Detection and Ranging (LiDAR) and Geographic Information Systems (GIS applications in a digital platform for landscape and structure consideration. The project was performed in combination with Global Positioning Systems (GPS), videography, and imaging documentation, with the 3D terrestrial laser scanning providing the referent data for the derived 3D Computer Assisted Drawing (CAD) products and archival as-is conditional reference. THis report presents the methodology and results of the project.
A Desktop System for Attack-Resistance and Rapid Recovery (2010)

General-purpose computing devices, such as PCs, and the operating systems that run on them provide more functionality and capabilities than most users will ever want or need. Too much of the burden of keeping these computer systems secure is placed on the end users. Users are often required to keep the operating system, applications, security software, and anti-virus definitions up-to-date. Even with the latest security updates, users are still susceptible to the newest exploits. When a system does become compromised, the process of then restoring it to a usable state can frequently result in the loss of personal data stored on the system. Personal data can often only be recovered through repeated effort and in some cases can never be recovered. In addition to problems caused by malicious software (malware), software bugs and conflicting software packages can also cause system instability and data corruption. This book describes a unique desktop system architecture solution to the pervasive problem of recovering from malware attacks. The open source Rapid Recovery Desktop system provides resistance against attack and rapid recovery from broken system state and malware infestation.
Passive-Active Geometric Calibration for View-Dependent Projections onto Arbitrary Surfaces (2024)

In this paper we present a hybrid technique for correcting distortions that appear when projecting images onto geometrically complex, colored and textured surfaces. It analyzes the optical flow that results from perspective distortions during motions of the observer and tries to use this information for computing the correct image warping. If this fails due to an unreliable optical flow, an accurate -but slower and visiblestructured light projection is automatically triggered. Together with an appropriate radiometric compensation, view-dependent content can be projected onto arbitrary everyday surfaces. An implementation mainly on the GPU ensures fast frame rates.