gebhart/patrepeval huggingface dataset:
Managing I/O Interference in a Shared Burst Buffer System (2016)

In this work, we investigate the problem of inter-application interference in a shared Burst Buffer (BB) system. A BB is a new storage technology for HPC architectures that acts as an intermediate layer between performance-hungry HPC applications and the slow parallel file system. While the BB is meant to alleviate the problem of slow I/O in HPC systems, it is itself prone to performance degradation under interference. We observe that the magnitude of interference effects can reach a level that matters to the HPC system and the jobs that run on it. We investigate I/O scheduling techniques as a mechanism to mitigate BB I/O interference. With our results, we show that scheduling techniques tuned to BBs can control interference and significant performance benefits can be achieved.
Accurate and Robust Neural Networks for Security Related Applications\n Exampled by Face Morphing Attacks (2018)

Artificial neural networks tend to learn only what they need for a task. A\nmanipulation of the training data can counter this phenomenon. In this paper,\nwe study the effect of different alterations of the training data, which limit\nthe amount and position of information that is available for the decision\nmaking. We analyze the accuracy and robustness against semantic and black box\nattacks on the networks that were trained on different training data\nmodifications for the particular example of morphing attacks. A morphing attack\nis an attack on a biometric facial recognition system where the system is\nfooled to match two different individuals with the same synthetic face image.\nSuch a synthetic image can be created by aligning and blending images of the\ntwo individuals that should be matched with this image.\n
Magnetic fluid flow meter for gases (1994)

The paper presents the constructive details and functioning principle of an electronic volumetric flow meter for gases, which exploits the properties of magnetic fluids and has no moving mechanical components. It is a bidirectional flow meter, operating both in static and in moving conditions. The flow meter has a sensing unit, which consists of two sensors, one for differential pressure and an other for acceleration or inclination angle and of a tubular measuring element, as well as an electronic measuring system. Details are given an the hydrodynamic-electronic correction mechanism, which eliminates the influences of inclinations and accelerations on the volumic flow signal, followed by a description of the main features of the electronic system. The experiments performed showed the possibility of metering even very small gas volumes, such as 0.1 cm/sup 3/ at a flow rate of 50 cm/sup 3//min. The metering at higher flow rate values, up to 100 m/sup 3//h, needed only the insert of the measuring element corresponding to the requested flow rate domain.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Aceclofenac–Galactose Conjugate: Design, Synthesis, Characterization, and Pharmacological and Toxicological Evaluations (2018)

Aceclofenac is a popular analgesic, antipyretic, and nonsteroidal anti-inflammatory drug (NSAID) used for prolonged treatment (at least three months) in musculoskeletal disorders. It is characterized by several limitations such as poor water solubility and low oral bioavailability. The main side-effect of aceclofenac, as well as all NSAIDs, is the gastrotoxicity; among other adverse effects, there is the risk of bleeding since aceclofenac reversibly inhibits platelet aggregation. With the aim to reduce these drawbacks, we have designed, synthesized, and characterized, both in vitro and in vivo, an orally administrable pro-drug of aceclofenac (ACEgal). ACEgal was obtained by conjugating carboxyl group with the 6-OH group of d-galactose; its structure was confirmed by X-ray powder diffractometry. The pro-drug was shown to be stable at 37 °C in simulated gastric fluid (SGF-without pepsin, pH = 1.2) and moderately stable in phosphate buffered saline (PBS, pH = 7.4). However, it hydrolyzed in human serum with a half-life ( t<sub>1/2</sub>) of 36 min, producing aceclofenac. Furthermore, if compared to its parent drug, ACEgal was four-times more soluble in SGF. To predict human intestinal absorption, cell permeability in a Caco-2 model of aceclofenac and ACEgal was determined. Anti-inflammatory, analgesic, and ulcerogenic activities have been investigated in vivo. In addition, oxidative stress parameters (thiobarbituric acid reactive substances, TBARS, and glutathione, GSH) and platelet antiaggregatory activity both of parent drug and pro-drug were evaluated. Results clearly showed that the conjugation of aceclofenac to a galactose molecule improves physicochemical, toxicological (at gastric and blood level), and pharmacological profile of aceclofenac itself without changing intestinal permeability and antiplatelet activity (in spite the new sugar moiety).
Are nulliparous sandflies light-shy? (1988)

Journal Article Are nulliparous sandflies light-shy? Get access P.A. Gibb, P.A. Gibb 1Keble College, Oxford, OX1 3PY, UK Search for other works by this author on: Oxford Academic PubMed Google Scholar T.J.C. Anderson, T.J.C. Anderson 2London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT UK Search for other works by this author on: Oxford Academic PubMed Google Scholar C. Dye C. Dye ∗ 2London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT UK ∗Author to whom correspondence should be addressed. Search for other works by this author on: Oxford Academic PubMed Google Scholar Transactions of The Royal Society of Tropical Medicine and Hygiene, Volume 82, Issue 2, March-April 1988, Pages 342–343, https://doi.org/10.1016/0035-9203(88)90472-5 Published: 01 March 1988 Article history Received: 18 August 1987 Accepted: 03 November 1987 Published: 01 March 1988
Wireless, acoustically linked, undersea, magnetometer sensor network (2009)

This paper presents a magnetometer sensor node design that consists of a He3 nuclear precession total-field magnetometer, data acquisition and recording electronics, and acoustic modem for networking such nodes. Expounding, we describe the integration of an ultra-sensitive magnetometer with the support electronics just mentioned. Additionally, the fully integrated, stand-alone magnetometer sensor node's self-noise performance is presented and compared with reference magnetometers. Due to the induced noise of the earth's background field, magnetometer data from multiple sensors is required in order to maximize the system detection range, thereby minimizing the overall number of required nodes to cover a given area. Given the aversion to continuously streaming data via the acoustic communications network between pairs of sensors, an alternative method is presented to minimize this traffic while still detecting objects of interest in the presence of the earth's field, with the cost being decreased detection ranges. Preliminary filtering techniques and an autoregressive process for implementing a noise whitening filter in addition to the application of orthonormal basis functions based on Anderson functions increase the single sensor detection range in the 0.001 to 0.030 Hz band representative of a passing vessel relative to the stationary sesnor. The filter's noise suppression performance conducted onboard a single sensor and application to collected data is presented.
Programmable array microscopy with a ferroelectric liquid-crystal spatial light modulator (2000)

We present a programmable array microscope that uses a ferroelectric liquid-crystal spatial light modulator (SLM) for dynamic generation of scanning apertures. A single SLM serves as both the source and the detector aperture array in a double-pass confocal system. Successive aperture frames scan the array across the viewing area for complete imaging of a sample while preserving depth discrimination. Integration of the microscope output across all aperture frames produces a confocal image.
Effects of Zinc on the New Preparation Method of Hydroxy Double Salts (1999)

In this study, a new preparation method of hydroxy double salts (HDSs) including organic compounds between layers has been established in which the HDSs were prepared by reacting ZnO with organic metal salts in water. This method does not need an anion-exchange reaction to incorporate organic compounds into the HDS layers. Moreover, the reaction proceeds under mild conditions around room temperature, and the obtained HDSs showed high crystallinity compared to those obtained by an anion-exchange reaction. We prepared ZnO crystals having a thin-plate structure by the thermal treatment of hydroxy zinc acetate at 873 K.
Homelandfans op online fan-communities (2013)

De brede beschikbaarheid van internet biedt de consument een grote variatie aan mogelijkheden om te participeren op fora, social media en interactieve websites. O’Reilly (2005) noemt deze media ook wel web 2.0 platformen. Middels deze platformen ventileren consumenten hun mening over uiteenlopende producten. De mening die het publiek deelt blijkt in toenemende mate belangrijk bij de afweging tot het consumeren van producten (Blank, 2007). Mond tot mondreclame over bijvoorbeeld films kan leiden tot een toename in de verkoop (Duan, Gu & Whinston, 2008). Dergelijke theorie is wellicht ook toepasbaar op televisieseries. Naast reclame voor het product wordt verondersteld dat producenten van televisieseries, middels platformen waar discussies van consumenten plaatsvinden, feedback verzamelen over door hun geproduceerde televisiecontent (Andrejevic, 2008). Vaak hebben deze producenten daarvoor eigen discussieplatformen en Facebookpagina’s opgericht. Op deze pagina’s zijn het voornamelijk de actieve fans (amateurs) die uitgebreid hun serie bespreken en hier een oordeel over geven. Maar hoe beoordelen zij deze series? Aan de hand van welke thema’s doen zij dit? En verschilt dit van de manier waarop professionele recensenten dit doen?
Dit onderzoek zal middels een kwalitatieve analyse van 1067 forumberichten en 10 professionele recensies een inzicht geven in de manier waarop fans en professionals oordelen over de televisieserie Homeland. Vanwege de centrale rol van politieke en controversiele thema’s in de serie zal extra aandacht uitgaan naar de rol van deze thema’s in het vormen van het oordeel. Fans blijken verregaande kennis te hebben over hun favoriete series en daardoor in staat een onderbouwd oordeel over deze series te geven (Andrejevic, 2008; Bielby & Bielby, 2004). De vraag is aan de hand van welke thema’s het publiek de fora gebruikt voor het oordelen over televisieseries en welke verschillen er te zien zijn met professionals en de manier waarop de verschillende onderzochte platformen gebruikt worden. Uit het onderzoek blijkt dat amateurs inderdaad een onderbouwd oordeel geven over hun serie, en dat de manier waarop zij dit doen verschilt van professionals. Ook de verschillende fora blijken invloed te hebben op de manier waarop discussie tussen fans plaatsvindt.
A Unified Performance Analysis of Cooperative NOMA With Practical Constraints: Hardware Impairment, Imperfect SIC and CSI (2022)

Non-orthogonal multiple access (NOMA) has been a strong candidate to support massive connectivity in future wireless networks. In this regard, its implementation into cooperative relaying, named cooperative-NOMA (CNOMA), has received tremendous attention from researchers. However, most of the existing CNOMA studies have failed to address practical constraints since they assume ideal conditions. Particularly, the error performance of CNOMA schemes with imperfections has not been investigated yet. In this paper, we provide an analytical framework for error and outage performance of CNOMA schemes under practical assumptions where we take into account imperfect successive interference canceler (ipSIC), imperfect channel state information (ipCSI), and hardware impairments (HWI) at the transceivers.We derive analytical expressions of bit error rate (BER) expressions in CNOMA schemes whether the direct links between source and users exist or not which is, to the best of the authors’ knowledge, the first study in the open literature. We also derive the outage probability (OP) expressions for CNOMA schemes with and without direct links under practical assumptions. For comparisons, we provide BER and OP expressions for downlink NOMA with practical constraints which also have not been given in the literature, yet. The theoretical BER and OP expressions are validated with computer simulations where the perfect match is observed. Finally, we discuss the effects of the system parameters (e.g., power allocation, HWI level, ipCSI factor) on the performance of CNOMA schemes to reveal fruitful insights for society. The results demonstrate that the HWI, ipCSI and ipSIC have a significant effect on the performance of the systems.
Systematic review of laryngeal reinnervation techniques (2010)

Reinnervation is effective in the management of UVFP, although the specific method may be dictated by anatomical limitations. Prospective studies utilizing uniform and consistent outcome parameters are necessary.
Far-infrared polarimetry (1995)

Airborne observations with the The University of Chicago polarimeter, Stokes (Platt et al. 1991), have produced maps of far infrared polarization over large areas in molecular clouds. Subsequent papers will discuss the implications of the results concerning the magnetic fields of individual objects. Our purpose here is to show a broad sample of the results and to point out certain general characteristics of the polarized emission.
Long-term results of total abdominal colectomy for chronic idiopathic constipation (1996)

Total abdominal colectomy with ileorectal anastomosis is highly effective in alleviating symptoms in patients with chronic idiopathic constipation.
Genetic landscape of adult Langerhans cell histiocytosis with lung involvement (2019)

The clinical significance of the <i>BRAF</i> <sup>V600E</sup> mutation in adult Langerhans cell histiocytosis (LCH), including pulmonary Langerhans cell histiocytosis (PLCH), is not well understood. Similarly, the spectrum of molecular alterations involved in adult LCH has not been fully delineated. To address these issues, we genotyped a large number of adult LCH biopsies and searched for an association of identified molecular alterations with clinical presentation and disease outcome.Biopsies from 117 adult LCH patients, 83 with PLCH (median age 36.4 years, 56 females, 38 multisystem disease, 79 single system disease, 65 current smokers) were genotyped for the <i>BRAF</i> <sup>V600E</sup> mutation. In 69 cases, LCH lesions were also genotyped by whole-exome sequencing (WES) or targeted gene panel next-generation sequencing (NGS). Cox models were used to estimate the association of baseline characteristics with the hazard of LCH progression.MAPK pathway alterations were detected in 59 out of 69 cases (86%) (<i>BRAF</i> <sup>V600E</sup> mutation: 36%, <i>BRAF</i> <sup>N486_P490</sup> deletion: 28%, <i>MAP2K1</i> mutations: 15%, isolated <i>NRAS</i> <sup>Q61</sup> mutations: 4%), while <i>KRAS</i> mutations were virtually absent in PLCH lesions. The <i>BRAF</i> <sup>V600E</sup> mutation was not associated with LCH presentation at diagnosis, including smoking status and lung function, in PLCH patients. <i>BRAF</i> <sup>V600E</sup> status did not influence the risk of LCH progression over time.Thus, MAPK alterations are present in most lesions from adult LCH patients, particularly in PLCH. Unlike reports in paediatric LCH, <i>BRAF</i> <sup>V600E</sup> genotyping did not provide additional information on disease outcome. The search for alterations involved in the MAPK pathway, including <i>BRAF</i> deletions, is useful for guiding targeted treatment in selected patients with refractory progressive LCH.
Growth Cone Localization of the mRNA Encoding the Chromatin Regulator HMGN5 Modulates Neurite Outgrowth (2015)

Neurons exploit local mRNA translation and retrograde transport of transcription factors to regulate gene expression in response to signaling events at distal neuronal ends. Whether epigenetic factors could also be involved in such regulation is not known. We report that the mRNA encoding the high-mobility group N5 (HMGN5) chromatin binding protein localizes to growth cones of both neuron-like cells and of hippocampal neurons, where it has the potential to be translated, and that HMGN5 can be retrogradely transported into the nucleus along neurites. Loss of HMGN5 function induces transcriptional changes and impairs neurite outgrowth, while HMGN5 overexpression induces neurite outgrowth and chromatin decompaction; these effects are dependent on growth cone localization of Hmgn5 mRNA. We suggest that the localization and local translation of transcripts coding for epigenetic factors couple the dynamic neuronal outgrowth process with chromatin regulation in the nucleus.
Upregulation of integrin expression in benign vulvar warts (1995)

Benign anogenital warts demonstrate features both of hyperproliferation and of aberrant differentiation associated with human papillomavirus (HPV) infection. The expression of integrins has been examined in normal vulvar epithelium and benign vulvar warts to determine whether HPV infection is associated with changes in integrin expression, either during terminal differentiation or among the proliferating cell population. The expression of integrins in normal vulvar epithelium was similar to that seen in the epidermis, with little expression of alpha 1 and expression of alpha 2, alpha 3, and beta 1 at the periphery of basal cells. In vulvar wart epithelium, alpha 1 was not significantly expressed, but upregulation of alpha 2, alpha 3, and beta 1 was seen at the periphery of cells throughout the basal and spinous layers. In addition, alpha 2 staining was greater at foci along the basal layer of normal vulva, whilst such heterogeneity was not detected in wart sections. Expression of beta 4 and alpha V was confined to the basal and lateral aspects of normal basal cells, but expressed at the periphery of basal cells and to a lesser extent in epibasal and spinous layers of warts. The observed differences in integrin expression are consistent with those reported in other hyperproliferative epithelia.
Assessment of the antimalarial potential of tetraoxane WR 148999. (2000)

The antimalarial peroxide, dispiro-1,2,4,5-tetraoxane WR 148999, was synergistic with chloroquine, quinine, mefloquine, and artemisinin against both D6 and W2 clones of Plasmodium falciparum. In consideration of the contrasting antagonism between artemisinin and chloroquine, these drug combination data imply that WR 148999 and artemisinin may not share a common mechanism of action. For Plasmodium berghei-infected mice given oral, subcutaneous, and intraperitoneal doses of WR 148999 ranging from 2 to 1024 mg/kg in the Thompson test, median survival times were 8.8, 11.8, and 27.5 days, respectively, compared to 8 days for control animals. Using subcutaneous administration, WR 148999 had a considerably longer duration of action than did artemisinin against P. berghei. WR 148999 did not significantly inhibit cytochrome P450 isozymes CYP 2C9, 2C19, 2D6, 2E1, or 3A4 (IC50 >500 microM) but did inhibit CYP 1A2 with an IC50 value of 36 microM, suggesting that WR 148999 may be metabolized by the latter CYP isozyme. These results combined with previous observations that formulation strategies and incorporation of polar functional groups in a series of WR 148999 analogs both failed to enhance tetraoxane oral antimalarial activity suggest that oral bioavailability of tetraoxane WR 148999 is more likely a function of extensive first-pass metabolism rather than solubility-limited dissolution.
Automatic registration of multi-source medium resolution satellite data (2014)

Abstract. Multi-temporal and multi-source images gathered from satellite platforms are nowadays a fundamental source of information in several domains. One of the main challenges in the fusion of different data sets consists in the registration issue, i.e., the integration into the same framework of images collected with different spatial resolution and acquisition geometry. This paper presents a novel methodology to accomplish this task on the basis of a method that stands out from existing approaches. The whole data (time series) set is simultaneously co-registered with a two-dimensional multiple Least Squares adjustment with different geometric transformations implemented. Some tests were carried out with different geometric transformation models (including similarity, affine, and polynomial) and variable matching thresholds. They showed a sub-pixel precision after the computation of multiple adjustment. The use of multi-image corresponding points allowed the improvement of the registration accuracy and reliability of a time series made up of data imaged with different sensors.
Low zinc in drinking water is associated with the risk of type 1 diabetes in children (2010)

Low zinc in drinking water is associated with the risk of developing type 1 diabetes during childhood. Enterovirus does not seem to be spread via drinking water in a country with modern water works.
Bubbles and Blisters Impact on Diecasting Cage to the Designs and Operations of Line-Start Synchronous Reluctance Motors (2017)

This study investigates the starting capability of a high-efficiency synchronous reluctance motor for direct online industrial applications. Because of structural limitations, line-start synchronous reluctance motors (LS-SynRMs) are commonly diecasted by reducing pressure to ensure safe manufacturing. Hence, the shape of the squirrel-cage bars, including bubbles and blisters in the rotors of LS-SynRM, needs to be analyzed. In this paper, three different models are proposed to model the random bubble and blister phenomena by using 2-D finite-element analysis (FEA); their impacts on the flux paths and the change in exciting current of the squirrel-cage bars due to the unbalanced bubbles are thoroughly evaluated. Finally, consider that the bubbles' impacts are confirmed by manufacturing the prototype motor and performing the experiment. The results of FEA and the experiment clearly indicate that the impacts of additional bubbles and blisters need to be considered in the design of LS-SynRMs.
Development of a Low-Cost Vortex-Cooled Thrust Chamber Using Hybrid Fabrication Techniques (2011)

Through an internally-funded effort, Orbital Technologies Corporation (ORBITEC) has developed a reaction control thruster that demonstrates a new approach to rocket propulsion hardware implementation. This new method has the potential to significantly reduce the cost and complexity of designing and fabricating aerospace combustion devices. The key features of the thruster, designated the MAELSTROMG25, are the use of ORBITEC’s patented vortex-cooled combustion chamber in conjunction with a new manufacturing approach called hybrid fabrication. These two innovations provide avenues to reduced cost through enhanced design flexibility, increased freedom in material selection, minimized heat loads on the thrust chamber assembly, and shortened design-build cycles.