gebhart/patrepeval huggingface dataset:
25th Anniversary Article: High‐Mobility Hole and Electron Transport Conjugated Polymers: How Structure Defines Function (2014)

The structural organization of three different families of semicrystalline π-conjugated polymers is reported (poly(3-hexylthiophene) (P3HT), poly[2,6-(4,4-bis-alkyl-4H-cyclopenta-[2,1-b;3,4-b0]-dithiophene)-alt-4,7-(2,1,3-benzothiadiazole)](cyclopentadithiophene-benzothiadiazole) (CDT-BTZ) and poly(N,N"-bis-2-octyldodecylnaphtalene-1,4,5,8-bis-dicarboximide-2,6-diyl-alt-5,5-2,2-bithiophene (P(NDI2OD-T2))). These have triggered significant interest for their remarkable charge-transport properties. By performing molecular mechanics/dynamics simulations with carefully re-parameterized force fields, it is illustrated in particular how the supramolecular organization of these conjugated polymers is driven by an interplay between the length and nature of the conjugated monomer unit and the packing of their alkyl side chains, and to what extent it impacts the charge-carrier mobility, as monitored by quantum-chemical calculations of the intermolecular hopping transfer integrals. This Progress Report is concluded by providing generic guidelines for the design of materials with enhanced degrees of supramolecular organization.
Photochemistry of Squaraine Dyes. 8. Photophysical Properties of Crown Ether Squaraine Fluoroionophores and Their Metal Ion Complexes (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhotochemistry of Squaraine Dyes. 8. Photophysical Properties of Crown Ether Squaraine Fluoroionophores and Their Metal Ion ComplexesSuresh Das, K. George Thomas, K. J. Thomas, Prashant V. Kamat, and M. V. GeorgeCite this: J. Phys. Chem. 1994, 98, 37, 9291–9296Publication Date (Print):September 1, 1994Publication History Published online1 May 2002Published inissue 1 September 1994https://pubs.acs.org/doi/10.1021/j100088a033https://doi.org/10.1021/j100088a033research-articleACS PublicationsRequest reuse permissionsArticle Views573Altmetric-Citations73LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Pathogenicity of a Birnavirus to Hard Clam(Meretrix lusoria) and Effect of Temperature Stress on Its Virulence. (1994)

A birnavirus, CV-TS-1 strain isolated from cultured hard clam (Meretrix lusoria) was inoculated to the hard clam by means of intrapalleal cavity injection or water borne method at 25°C. Cumulative mortalities of clams injected with the virus at the concentrations of 104.7, 103.7 and 102.7 TCID50/clam were 37.5%, 32.5% and 25%, and those of clams immersed to virus solutions of 106.0, 105.0and 104.0TCID50/mlwere 30%, 25% and 15%, respectively. Temperature stress (increase from 25°Cto 33°C or decrease from 25°C to 15°C) was given to clams before and after virus challenge by exposure to a virus solution of 105.0 TCID50/ml. Mortality increased markedly when temperature was increased after virus infection, though either the decrease in temperature after virus challenge or increase or decrease in temperature before the challenge did not affect the mortality.
Treatment of Nasal Inflammation Decreases the Ability of Subjects with Asthma to Condition Inspired Air (2004)

We previously showed that individuals with seasonal allergy have a reduced ability to condition air, which was improved by nasal inflammation. We also showed that subjects with asthma have a reduced ability to condition air. Because individuals with asthma usually have inflammation in the nose, we hypothesized that treatment with an intranasal steroid would reduce nasal inflammation and further decrease nasal conditioning capacity. We performed a randomized, double blind, placebo-controlled, 2-way crossover study on 20 subjects with asthma comparing the effect of treatment with intranasal budesonide for 2 weeks on nasal conditioning. Treatment with budesonide caused no significant effect on nasal conditioning as compared with placebo. When we evaluated the subgroup of nonsmoking subjects, budesonide caused a significant reduction in nasal conditioning. We speculate that nasal inflammation in nonsmoking individuals with asthma increases the conditioning capacity and reducing it with an intranasal steroid worsens the ability of the nose to condition air. In addition, smoking causes an increase in nasal conditioning capacity by non-steroid-dependent factors. These observations help us understand the pathophysiology of nasal conditioning, but do not negate the positive clinical benefits of budesonide on treating nasal inflammation.
Multimodels and dynamic structure models: an integration of DSDE/DEVS and OOPM (1998)

Constructing models of systems that change their structure over time has proved to be a challenging problem, with several proposed solutions. We present two of these approaches and discuss their integration. The parallel Dynamic Structure Discrete Event (DSDE) system specification is based on systems-theoretic concepts and provides a formal specification of variable structure models. Object-oriented physical modeling (OOPM) extends the design approaches of software engineering and employs both static and dynamic models to describe physical objects. OOPM is based on the multi-model concept to support adaptive structures. The integration is achieved by representing multi-models within the dynamic-structure Discrete Event System Specification (DEVS) formalism. Since the latter has been implemented in HLA (High-Level Architecture) compliant form, the integration has the practical consequence that multi-models can be directly mapped into distributed simulations.
Integrated somatic subtypes of localized intermediate-risk prostate cancer. (2017)

e560 Background: Approximately two thirds of intermediate risk prostate cancer patients are over- or under- treated because we cannot correctly prognose this risk group; therefore we require novel biomarkers to better direct patient therapies and avoid subjecting patients to side effects without benefit. One reason genomic biomarkers are not currently used in clinical settings is because they are notoriously difficult to validate in follow-up studies. Furthermore, the lack of clear prostate cancer subtypes prevents the development of subtype specific biomarkers as is standard practice in breast cancer. We aim to improve biomarker validation rates by defining prostate cancer subtypes that can be used to create subtype specific biomarkers. Methods: First, we assess large scale genomic patterns using whole genome sequencing and methylation data and create integrative subtypes for intermediate risk prostate cancer. Second, we assess associations between specific aberrations and subtypes, and determine whether certain types of molecular aberrations are more important background aberrations for subtype specific biomarker development. Finally, we assess biases in prognostic performance of the published Lalonde biomarker between groups associated with patient subtypes to show that subtype aware biomarkers are necessary. Results: We demonstrate that the Lalonde biomarker is biased by the cohorts’ proportion of TMPRSS2-ERG (T2E) aberrations illustrating the need to develop different biomarkers for patients with T2E and patients without T2E. Further, we suggest integrative subtypes can be used to select patients with similar genomic profiles for biomarker analysis to improve biomarker validation rates. Conclusions: This analysis provides direct guidance for future biomarker development and addresses an important barrier to clinical use of genomic biomarkers for prostate cancer.
Studies on analogs of DAMASCENOLIDETM: Part 4. Synthesis and odor evaluation of sulfur-containing analogs of DAMASCENOLIDETM (2021)

DAMASCENOLIDETM [1, 4-(4-methylpent-3-en-1-yl)furan-2(5H)-one], which is isolated from damask rose, is a useful aroma compound with a citrus-like odor. We have previously reported on the synthesis and odor properties of 34 analogs of 1 as part of our new aroma compound development project. In order to develop better aroma compounds and to gather more information on structure-odor relationships, 6 novel sulfur-containing analogs of 1 were synthesized. Odor evaluation revealed that their odors differed significantly from those of the corresponding sulfur-free compounds. The introduction of a sulfur atom does not necessarily result in a sulfur-like odor. In particular, the 2(5H)-thiophenone analogs gave waxy, oily, and lactone-like odors that are uncharacteristic of sulfur-containing compounds. In many synthesized analogs, the introduction of a sulfur atom led to an increase in odor intensity, as expected.
Prelamin A Accelerates Vascular Calcification Via Activation of the DNA Damage Response and Senescence-Associated Secretory Phenotype in Vascular Smooth Muscle Cells (2013)

Prelamin A promotes VSMC calcification and aging by inducing persistent DNA damage signaling, which acts upstream of VSMC osteogenic differentiation and the senescence-associated secretory phenotype. Agents that target the DNA damage response and prelamin A toxicity may be potential therapies for the treatment of vascular calcification.
Assessment of the attenuation of an intra-abdominal vein by use of a silicone–polyacrylic acid gradual venous occlusion device in dogs and cats (2016)

OBJECTIVE To evaluate the closure rate and completeness of closure for a silicone-polyacrylic acid gradual venous occlusion device placed around an intra-abdominal vein to simulate gradual occlusion of an extrahepatic portosystemic shunt. ANIMALS 3 purpose-bred cats and 2 purpose-bred dogs. PROCEDURES The device was surgically placed around an external (cats) or internal (dogs) iliac vein. Computed tomographic angiography was performed at the time of surgery and 2, 4, and 6 weeks after surgery. Ultrasonographic examinations of blood flow through the vein within the device were performed at the time of surgery and at weekly intervals thereafter. Dogs were euthanized 6 weeks after surgery, and the external iliac veins were harvested for histologic examination. RESULTS The prototype gradual venous occlusion device was successfully placed in all animals, and all animals recovered without complications following the placement procedure. The vessel was completely occluded in 2 cats by 6 weeks after surgery, as determined on the basis of results of CT and ultrasonography; there was incomplete occlusion with a luminal diameter of 1.5 mm in the other cat by 6 weeks after surgery. The vessel was completely occluded in both dogs by 6 weeks after surgery. Histologic examination of the external iliac veins obtained from the dogs revealed minimal inflammation of the vessel wall and no thrombus formation. CONCLUSIONS AND CLINICAL RELEVANCE The prototype device induced gradual attenuation of an intra-abdominal vessel over a 6-week period. This device may provide another option for gradual occlusion of extrahepatic portosystemic shunts.
Symmetry Reduction for STE Model Checking (2006)

In spite of the tremendous success of STE model checking one cannot verify circuits with arbitrary large number of state holding elements. In this paper we present a methodology of symmetry reduction for STE model checking, using a novel set of STE inference rules. For symmetric circuit models these rules provide a very effective reduction strategy. When used as tactics, rules help decompose a given STE property to a set containing several classes of equivalent STE properties. A representative from each equivalence class is picked and verified using an STE simulator, and the correctness of the entire class of assertions is deduced, using a theorem that we provide. Finally inference rules are used in the forward direction to deduce the overall statement of correctness. Our experiments on verifying arbitrarily large CAMs and circuits with multiple CAMs, show that these can be verified using a fixed, small number of BDD variables
COVID-19 Case and Mortality Surveillance using Daily SARS-CoV-2 in Wastewater Samples adjusting for Meteorological Conditions and Sample pH (2023)

Time lagged wastewater SARS-CoV-2 (and its adjustment for sample pH and RNA recovery) and meteorological conditions can be used for the surveillance of COVID-19 case and mortality. These findings can be extrapolated to improve the surveillance of other infectious diseases by proactive measurements of infectious agent(s) in the wastewater samples, adjusting for meteorological conditions and sample pH value.
Autism spectrum disorders : identification of novel microdeletions and microduplications and their associated phenotypes (2009)

Background: Autism Spectrum Disorders (ASDs) are common, heritable neurobiologic conditions of unknown etiology confounded by significant clinical and genetic heterogeneity. In recent years, array CGH technology has been used to rapidly screen the genome for pathogenic copy number variants (PCNVs) associated with ASDs and data from 6 studies suggests that PCNVs contribute to ASD pathogenesis in 6-27% of cases. However, the role of PCNVs in ASDs remains poorly understood, due to the absence of comprehensive phenotyping of ASD subjects. Methods: To address this, we collected detailed clinical, medical, physical and morphologic information on all subjects and investigated whether these phenotypes would be good indicators of PCNV risk. We studied somatic phenotypes, as opposed to behavioural indices that change over time and with treatment, in an attempt to provide better evidence for the biological/embryological origin of ASDs and help define new ASD syndromes. Results: Seven disease-specific and potentially pathogenic CNVs were uncovered in 6/40 patients (15%). Two changes were de novo and 5 were inherited from normal parents, but had never been reported in normal populations before. All PCNVs were discovered in individuals without family history of autism, ranged in sizes from 175kb to 2.5Mb, and revealed 9 good candidate genes. Our results suggest that whilst no single phenotypic feature investigated associates with PCNV risk, there is an indication that the presence of phenotypic abnormalities involving multiple body areas may be a better indicator of PCNVs in ASDs than the presence or number of minor physical anomalies alone. In addition, our findings lend support to the idea that complex autism, involving significant dysmorphology, is etiologically distinct from essential autism, with an increased prevalence of ID, seizures and health problems, and a higher proportion of individuals without family history of ASDs. Conclusion: We identified novel areas of chromosomal imbalance associated with ASDs and provide detailed phenotypic information for every subject for which these new PCNVs were detected. The extensive phenotyping of affected individuals carrying clinically relevant CNVs is needed in order to understand their role in the etiology of autism and ultimately provide earlier and more reliable means for ASD diagnosis and treatment.
Continuous-wave Nd:Yag laser hyperthermia: a successful modality in treatment of basal cell carcinoma (2004)

It was observed that malignant tumor cells are more sensitive than normal cells to heat. Hyperthermia is known to be cytotoxic at temperatures above 41 degrees C and selectively lethal to cancer cells. The aim of the present study was to evaluate the therapeutic efficacy of continuous wave Nd:Yag laser-induced hyperthermia in treatment of basal cell carcinoma (BCC). The study was performed between April 1995 and August 2000 on 37 patients with BCC selected from of the outpatients of the dermatology clinic of al-Minya University Hospital. Patients were treated with continuous-wave Nd:Yag laser hyperthermia at 6-week intervals (laser output power was 10 W, spot size 8 mm, and irradiation time up to 1 minute). Following this treatment, 36 patients (97.3 %) were completely cured. Within a follow-up period of 3-5 years only one recurrence was encountered (2.7 %). Continuous wave Nd:Yag laser-induced hyperthermia should be considered as an alternative treatment for BCC. This simple, bloodless, outpatient procedure showed excellent efficacy and cosmetic result with minimal complication.
Cecil Green receives Smith Medal (1995)

The Waldo E. Smith Medal, which is awarded for extraordinary service to geophysics, was presented to Cecil H. Green at the 1994 AGU Fall Meeting Honors Ceremony on December 7, 1994 in San Francisco. The award citation and Green's response are given here. “It would take a book to do justice to Cecil Green's extraordinary contributions to the geophysics and electronics industries, to the training of scientists, physicians, and engineers, and to strengthening education and research institutions. In fact, such a book has been written about Cecil's multiple lives as engineer, geophysicist, cofounder of Texas Instruments, and partner with his wife, Ida, in international philanthropy.
A method for oxygen isotope analyses of organic material (1974)

A technique has been developed to measure 18 O/ 16 O ratios in milligram amounts of organic material. The organic material is pyrolyzed at 1250°C in the presence of diamonds (easily outgassed carbon source) as the reducing agent. The carbon monoxide formed is converted to carbon dioxide by a high voltage discharge, and the CO 2 is analyzed on a mass spectrometer. The precision of the method is ±0.35 permil (1 sigma).
Real-time moving automotive vehicle identification system (AVIS) (2002)

A real-time moving automotive vehicle identification system (AVIS) has been developed for intelligent vehicle highway systems (IVHS). AVIS consists of 3 major elements: invisible bar-code material, optical scanner, and DSP board. The invisible bar-code material reflects only the specific wavelength light (1500 nm). The optical scanner developed can read the invisible bar-code data only at the corresponding wavelength light. The TI TMS320C31 digital signal processing (DSP) board has been implemented. The DSP board processes the bar-code data obtained from the optical scanner through the invisible bar-code. The DSP board operates at 33 MHz with the image processing algorithm which includes error-detecting and error-correcting capabilities. The system has been tested and the results show that the AVIS performed successfully. The AVIS is expected to be applied to the non-stop toll gate and violation enforcement system.
Studies on 12 cell lines established from mononuclear leukocytes of cattle with lymphosarcoma (1968)

The material and methods used in establishing 12 cell lines from four cattle with histopathologically confirmed lymphosarcoma are described. Findings suggest that the type of serum used to supplement the culture medium is important. Chromosome studies have shown that all the cell lines are aneuploid and indicate that the cells in culture are neoplastic cells derived from the neoplastic cells of the diseased animals. Preliminary electron-microscopic studies have failed to reveal virus-like particles.
Use of Nanohydroxyapatite in Regenerative Therapy in Dogs Affected by Periodontopathy: Preliminary Results (2015)

Guided Tissue Regeneration (GTR) is one of the latest techniques introduced for regenerative purposes in the control of this disease. It aims to rebuild tissues compromised by PD, restoring them to their original condition by utilizing barrier
GLU3.0: Fast GPU-based Parallel Sparse LU Factorization for Circuit Simulation (2020)

Editor's note: Many scientific computing problems, including circuit simulations, rely on efficient lower-upper (LU) decomposition of sparse matrices. Prior studies took advantage of GPUs to parallelize LU decomposition, but they suffer from nontrivial data dependencies. This article presents a new method, called GLU3.0, to accelerate GPU-based sparse LU factorization. -Umit Ogras, Arizona State University.
Study of the effect of fumed silica on rigid PVC properties (1993)

Abstract This study seeks to substitute fumed silica for chlorinated polyethylene (CPE) within a rigid PVC formulation intended for profile extrusion such as doors and window frames. The effect of fumed silica on both mechanical (tensile and impact) and thermal (Vicat point, HDT, and linear thermal expansion coefficient) properties were investigated. Five rigid PVC formulations were prepared, including a reference one (F 1 ), then F 1 with CPE, F 1 with untreated silica, F 1 with heat treated silica, and finally F 1 with dried silica and a coupling agent. The effect of CPE on mechanical properties was very modest. On the other hand, CPE showed its inefficiency, in that HDT and Vicat point were decreased. Heat treated silica showed the greatest improvement in both mechanical and thermal properties. Untreated silica showed a small effect on both properties. Finally, the incorporation of coupling agent gave considerable improvement in both mechanical and thermal properties.
PV-MCT working standard radiometer (2012)

Sensitive infrared working-standard detectors with large active area are needed to extend the signal dynamic range of the National Institute of Standards and Technology (NIST) pyroelectric transfer-standards used for infrared spectral power responsivity calibrations. Increased sensitivity is especially important for irradiance mode responsivity measurements. The noise equivalent power (NEP) of the NIST used pyroelectric transfer-standards is about 8 nW/Hz<sup>1/2</sup>, equal to a D*= 5.5 x 10<sup>7</sup> cm Hz<sup>1/2</sup>/W. A large-area photovoltaic HgCdTe (PV-MCT) detector was custom made for the 2.5 &mu;m to 11 &mu;m wavelength range using a 4-stage thermoelectric cooler. At least an order of magnitude lower NEP was expected than that of the pyroelectric transfer-standards to measure irradiance. The large detector area was produced with multiple p-n junctions. The periodical, multiple-junction structure produced a spatial non-uniformity in the detector response. The PV-MCT radiometer was characterized for spatial non-uniformity of response using different incident beam sizes to evaluate the uncertainty component caused by the spatial non-uniformity. The output voltage noise and also the current and voltage responsivities were evaluated at different signal gains and frequencies. The output voltage noise was decreased and the voltage responsivity was increased to lower the NEP of the radiometer. The uncertainty of the spectral power responsivity measurements was evaluated. It is recommended to use a bootstrap type trans-impedance amplifier along with a cold field-of-view limiter to improve the NEP of the PV-MCT radiometer.