gebhart/patrepeval huggingface dataset:
Sodium Dodecyl Sulfate Monomers Induce XAO Peptide Polyproline II to α-Helix Transition (2014)

chain, −CH2CH2CH2NH3+) in aqueous solution shows a predominantly polyproline II (PPII) conformation without any detectable α-helix-like conformations. Here we demonstrate by using circular dichroism (CD), ultraviolet resonance Raman (UVRR) and nuclear magnetic resonance (NMR) spectroscopy that sodium dodecyl sulfate (SDS) monomers bind to XAO and induce formation of α-helix-like conformations. The stoichiom-etry and the association constants of SDS and XAO were determined from the XAO−SDS diffusion coefficients measured by pulsed field gradient NMR. We developed a model for the formation of XAO−SDS aggregate α-helix-like conformations. Using UVRR spectroscopy, we calculated the Ramachandran ψ angle distributions of aggregated XAO peptides. We resolved α-, π- and 310- helical conformations and a turn conformation. XAO nucleates SDS aggregation at SDS concentrations below the SDS critical micelle concentration. The XAO4−SDS16 aggregates have four SDS molecules bound to each XAO to neutralize the four side chain cationic charges. We propose that the SDS alkyl chains partition into a hydrophobic core to minimize the hydrophobic area exposed to water. Neutralization of the flanking XAO charges enables α-helix formation. Four XAO−SDS4 aggregates form a complex with an SDS alkyl chain-dominated hydrophobic core and a more hydrophilic shell where one face of the α-helix peptide
Drinking water supplement containing organic acids and medium chain fatty acids induces significant changes in the intestinal microbiota and lowers incidence of diarrhoea of piglets post-weaning (2011)

Antibiotic treatment of piglets post-weaning may lead to re-occurring diarrhoea after stopping the antibiotic treatment. The objective of the study was to test the efficacy of a commercial drinking water supplement containing organic acids and medium chain fatty acids (Selko-4-Health ) on diarrhoea control in piglets weaned at 26 days of age. In total 244 piglets were allocated at weaning to 4 treatments in a 2x2 experimental design for the duration of 4 weeks. Piglets received either a non-medicated feed, oxytetracycline medicated feed (400 ppm) during the first week post weaning and thereafter no medication, a drinking water supplement during the whole experimental period or the combination of the two treatments. Jejunal samples were taken of 4 piglets from each treatment at 2 and 4 weeks post-weaning to examine the intestinal microbiota with 16SRNA gene-targeted Denaturant Gradient Gel Electrophoresis, quantitative PCR and the Pig Intestinal Tract Chip (PITChip), a diagnostic microarray custom-designed for the profiling of porcine intestinal microbiota. None of the treatments significantly affected performance. Both, the antibiotic treatment as the water supplement treatment significantly lowered the incidence of diarrhoea in week 2 and 3 post-weaning and in the overall experimental period (p<0.05), with no significant interaction between these treatments. The microbiota assays revealed a shift of the microbial profiles in time. Overall, the organic acid blend as well as oxytretracyclin had a significant effect on weaned piglet gut microbiota, with observed changes in Lactobacilli spp. composition (DGGE) and microbial profiles analysed with the PITChip. The results demonstrate that drinking water supplements containing organic acids and medium chain fatty acids can be applied in strategies to establish a prudent use of antibiotics in control of diarrhoea in piglets. More information is needed to understand the impact of intestinal microbiota changes in relation to occurrence of diarrhoea in piglets.
Instrumented an obstetrical forceps (2003)

New technologies and new methods in medical engineering was introduced in the medical world. With these technologies we can find a surgical instrumentation more and more adapted to carry out interventions. In obstetrics practice the doctor can use some instruments to delivery the baby, such as for example the obstetrical forceps. The obstetrical forceps has been in use for over 300 years with more than 700 variations of design, however, none of these allow the engineers to assess the force on the fetal skull. Cranial depressed fractures occur. We propose instrumented forceps to control the efforts of tightening on the fetus skull. The clinical and scientific consequences of such study are: the decrease of the number of accidents during a delivery with forceps, the help to the choice of the way of delivery, the improvement of the education, the increase of the knowledge of the compressives phenomenon bound to the final phase of the delivery and the participation in the prevention by the intelligent biomedical instrumentation.
Bismuth Basic Nitrate as a Novel Adsorbent for Azo Dye Removal (2011)

Bismuth basic nitrate (BBN) and its TiO 2 ‐Ag modified sorbent, PTBA were successfully synthesized via a precipitation method. The structural characteristics of prepared sorbents were determined through different analytical techniques. The potential use of prepared sorbents for organic compounds′ removal was evaluated using Methyl Orange and Sunset Yellow dyes as model pollutants in aqueous solutions. The experimental results showed that the presence of TiO 2 and Ag particles during the crystal growth of bismuth basic nitrate has an effect on the crystal structure, point of zero charge (pHpzc), pore volume and diameter. The lower binding energy of Ti 2p core level peak indicates the octahedral coordination of TiO 2 particles on the PTBA surface. The alteration of hydrophilic‐hydrophobic characteristics of sorbent′s surface improves the adsorptive performance of the modified sorbent and provides an efficient route for organic contaminants′ removal from aqueous solutions.
Three Dimensional Printing: Rapid Tooling and Prototypes Directly from CAD Representation (2018)

Industrial productivity and competitive success depend on fast, efficient product&#13;\ndevelopment technologies. The flexible manufacture of tooling and mechanical prototypes&#13;\ncan greatly reduce the time required for bringing a product to market. Tooling frequently&#13;\ndominates manufacturing time and cost, thereby determining the minimum economic batch&#13;\nsize for a given process. Tooling can be extremely complex and is generally one-of-a-kind,&#13;\nrequiring much human attention to detail. As a result, fabrication of tooling for such&#13;\nprocesses as injection molding or lost wax casting, commonly requires several months of&#13;\nwork. Three Dimensional Printing offers an alternative to conventional options which do&#13;\nnot adequately answer the demands for rapid prototyping and speedy, low-cost production&#13;\nof tooling.
Antioxidant and antibacterial activities of oleoresins isolated from nine Curcuma species (2012)

Oleoresins were extracted from rhizomes of nine starchy Curcuma species (Curcuma aeruginosa, Curcuma. amada, Curcuma aromatica, Curcuma brog, Curcume caesia, Curcuma malabarica, Curcuma rakthakanta, Curcuma sylvatica and Curcuma zedoaria) using dichloromethane and evaluated for antioxidant and antibacterial activity. The yield of oleoresin in the different species ranged from 4 to 15 % dry weight. Total phenols varied from 23 – 100 mg gallic acid equivalents (GAE) /g oleoresin. Oleoresins from all the species exhibited high DPPH radical scavenging activity and ferric reducing power, which had good correlation with phenolic content The oleoresins inhibited both g +ve (S. aureus and B. subtilis) and g-ve (E. coli) bacteria. Maximum sensitivity was observed in the case of B. subtilis. The results indicated that the oleoresins from these species (most of which are unutilized) would have good potential as additives for food and medicinal applications.
Selective Excitatory Amino Acid Uptake in Glutamatergic Nerve Terminals and in Glia in the Rat Striatum: Quantitative Electron Microscopic Immunocytochemistry of Exogenous D‐Aspartate and Endogenous Glutamate and GABA (1996)

To characterize glutamate/aspartate uptake activity in various cellular and subcellular elements in the striatum, rat striatal slices were exposed to 10 and 50 mu M exogenous (D)-aspartate. After fixation with glutaraldehyde/formaldehyde the distribution of (D)-aspartate was analysed by postembedding immunocytochemistry and the ultrastructural distribution was compared with the distributions of endogenous glutamate and GABA. Light microscopically, (D)-aspartate-like immunoreactivity was localized in conspicuous dots along very weakly labelled dendritic profiles and neuron cell bodies. At the electron microscope level gold particles signalling (D)-aspartate occurred at highest density in nerve terminals making asymmetrical contacts with postsynaptic spines (i.e. resembling synapses of cortical afferents). Astrocytic processes also contained gold particles, but at a lower density than nerve endings. In contrast, dendritic spines were only weakly (D)-aspartate-positive. The difference in labelling at 10 and 50 mu M (D)-aspartate was consistent with 'high-affinity' uptake. Neighbouring sections processed with other antibodies showed that the D-aspartate labelling. Occurred in nerve terminals strongly immunoreactive for glutamate, rather than in terminals very weakly glutamate-immunopositive or in nerve endings immunoreactive for GABA. Glutamate labelling of perfusion-fixed striatum confirmed that terminals forming asymmetrical synaptic contacts with spines were enriched with gold particles, suggesting that these terminals use glutamate as a transmitter. This study demonstrates that high-affinity uptake sites for excitatory amino acids in the striatum are most strongly expressed on presumed glutamatergic nerve terminals and on astrocytes.
Message Header Field for Indicating Message Authentication Status Status of This Memo This document specifies an Internet standards track protocol for the (2009)

This memo defines a new header field for use with electronic mail messages to indicate the results of message authentication efforts. Any receiver-side software, such as mail filters or Mail User Agents (MUAs), may use this message header field to relay that information in a convenient way to users or to make sorting and filtering decisions.
Inflammatory Mechanisms in HIV-Associated Pulmonary Arterial Hypertension (2013)

Pulmonary arterial hypertension (PAH) is a severe complication of human immunodeficiency virus (HIV) infection and a leading major cause of death when present. HIV-PAH could be the consequence of multiple hits including the direct effects of HIV proteins, use of illicit drugs, and chronic inflammation. Indeed, HIV infection has long been identified as an immunosuppressive disease but, since the advent of highly active antiretroviral treatments (HAART), HIV infection is considered as an inflammatory disease in which vascular complications have become a major cause of morbidity and death. Conversely to immunosuppression, which correlates with blood CD4 + T cell level, inflammation in HIV infection is due to the lack of gut CD4 + T cell restoration. Such gut T cell depletion favors lipopolysaccharide translocation and, in turn, chronic systemic interleukin-6 overproduction. Conversely to blood CD4 + T cells, gut CD4 + T cells are only partially restored with HAART, usually slowly after several months or years, with a large heterogeneity from one patient to another. These characteristics may cause chronic inflammation, and we hypothesize that PAH may occur because of this inflammatory component despite HAART, even with apparently good response to therapy (i.e., blood CD4 + T cell normalization and undetectable HIV load). Inflammation theory in HIV-PAH (as in other forms of PAH) could open new treatment options.
Effect of Test Parameters on Sensitivity of Tensile Test Results for Greige Cotton Hydroentangled Nonwoven Fabric (2022)

This research is an in-depth study into the tensile properties of hydro-entangled nonwoven fabrics made of greige cotton. The effect of five different testing parameters or sample characteristics, weight, gauge length, speed of testing, angle to machine direction, and specimen width, of hydro-entangled nonwoven fabrics made of greige cotton were correlated with load at break, extension at break, tensile stress at break, tensile strain at break, Young’s modulus, and energy at break. The regression equations with an average r 2 of 0.82 demonstrated parameters’ positive and effective influence on tensile properties. The influence order of all testing parameters is gauge length = specimen width &gt; speed. This analysis aims to study the effects of testing parameters or sample characteristics on tensile properties. It is hoped that this study can contribute a better understanding of the relationship between hydro-entangled nonwoven fabric mechanical performance and web formations, potentially promoting greige cotton applications.
Peer Reviewed: What Future for Carbon Capture and Sequestration? (2001)

ADVERTISEMENT RETURN TO ISSUEPREVFeaturesNEXTPeer Reviewed: What Future for Carbon Capture and Sequestration?New technologies could reduce carbon dioxide emissions to the atmosphere while still allowing the use of fossil fuelsHoward J. HerzogCite this: Environ. Sci. Technol. 2001, 35, 7, 148A–153APublication Date (Web):April 1, 2001Publication History Published online1 April 2001Published inissue 1 April 2001https://pubs.acs.org/doi/10.1021/es012307jhttps://doi.org/10.1021/es012307jnewsACS Publications. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views18827Altmetric-Citations414LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (33 MB) Get e-Alertsclose SUBJECTS:Carbon capture and storage Get e-Alerts
Phase Eaquilibria of the Fe-Ni-Al System for Al Content above 50 at.% and Crystal Structures of some Ternary Phases (1982)

Article Phase Eaquilibria of the Fe-Ni-Al System for Al Content above 50 at.% and Crystal Structures of some Ternary Phases was published on July 1, 1982 in the journal International Journal of Materials Research (volume 73, issue 7).
The pulmonary toxicity of carboxylated or aminated multi-walled carbon nanotubes in mice is determined by the prior purification method (2020)

These data demonstrate that the purification method is an important determinant of lung toxicity induced by carboxyl- and amine-functionalized MWCNTs.
An S/MAR-based L1 retrotransposition cassette mediates sustained levels of insertional mutagenesis without suffering from epigenetic silencing of DNA methylation (2010)

L1 is an insertional mutagen that is capable of mediating permanent gene disruption in mammalian genomes. However, currently available L1 retrotransposition vectors exhibit low or unstable transgene expression when expressed in somatic cells and tissues. This restriction limits their potential utility in long-term screening procedures or somatic mutagenesis applications. In this study, we addressed this problem by developing a minicircle, nonviral L1 retrotransposition vector using a scaffold/matrix attachment region (S/MAR) in the vector backbone and evaluated its utility in human cell lines. The S/MAR-based L1 retrotransposition vector provides stable, elevated levels of L1 expression compared to the currently used EBNA1-based L1 vector. In addition, the S/MAR elements effectively mediate sustained levels of L1 retrotransposition in prolonged cell culturing without suffering from epigenetic silencing by DNA methylation or from vector integration problems even in the absence of selection pressure. These findings indicate that the simple inclusion of S/MAR in the vector backbone increased levels of L1 expression and retrotransposition that can be used as an effective tool to generate insertional mutagenesis in large-scale somatic mutagenesis applications in mammalian cells.
Prozessgrenzen beim Honen thermischer Spritzschichten*/Process limits in honing of thermal spray coatings (2018)

Der Einsatz neuer Beschichtungswerkstoffe erfordert die Untersuchung des Honprozesses hinsichtlich Produktivität und Oberflächenqualität. Für den neuen Beschichtungswerkstoff FeCrBMn sind in Versuchen die Einflüsse der Prozessparameter auf das Zeitspanvolumen, den Werkzeugverschleiß und die Oberflächenqualität erarbeitet worden. Die Ergebnisse zeigen die Möglichkeiten für hohe Zeitspanvolumen und die erreichbaren Oberflächenqualitäten beim Honen der neuen Beschichtung FeCrBMn auf. &amp;nbsp; The use of new coating materials requires the investigation of the honing process with regard to productivity and surface finish quality. In experiments, the influence of the process parameters on the material removal rate, tool wear and surface quality was investigated. The results indicate the potential to achieve high material removal rates and good surface qualities by honing of the novel FeCrBMn coating.
Evaluating Parents and Adult Caregivers as “Agents of Change” for Treating Obese Children: Evidence for Parent Behavior Change Strategies and Research Gaps (2012)

This scientific statement addresses parents and adult caregivers (PACs) as "agents of change" for obese children, evaluating the strength of evidence that particular parenting strategies can leverage behavior change and reduce positive energy balance in obese youth. The statement has 3 specific aims. The first is to review core behavior change strategies for PACs as used in family-based treatment programs and to provide a resource list. The second is to evaluate the strength of evidence that greater parental "involvement" in treatment is associated with better reductions in child overweight. The third is to identify research gaps and new opportunities for the field. This review yielded limited and inconsistent evidence from randomized controlled clinical trials that greater PAC involvement necessarily is associated with better child outcomes. For example, only 17% of the intervention studies reported differential improvements in child overweight as a function of parental involvement in treatment. On the other hand, greater parental adherence with core behavior change strategies predicted better child weight outcomes after 2 and 5 years in some studies. Thus, the literature lacks conclusive evidence that one particular parenting strategy or approach causally is superior to others in which children have a greater focus in treatment. A number of research gaps were identified, including the assessment of refined parenting phenotypes, cultural tailoring of interventions, examination of family relationships, and incorporation of new technologies. A conceptual model is proposed to stimulate research identifying the determinants of PAC feeding and physical activity parenting practices, the results of which may inform new treatments. The statement addresses the need for innovative research to advance the scope and potency of PAC treatments for childhood obesity.
Hybrid Microstrip T-Stub/Defected Ground Structure Cell for Electromagnetic Interference Bandpass Filter Design (2011)

In this paper, the hybrid microstrip T-stub/defected ground structure (HMT/DGS) cell is presented, which is composed of a microstrip T-stub and an interdigital DGS with the broadside-coupled (BC) transition. Finely adjusted resonance can be achieved by the proposed cell. Meanwhile, strong slow-wave effect is employed by the structure, which leads to wide stopband responses. Based on these HMT/DGS cells, the interdigital-coupled scheme is employed to implement the electromagnetic interference (EMI) bandpass filter with high performance. To verify the aforementioned mechanism, two filters are designed and fabricated. Specifically, the second-order bandpass filter with a fractional bandwidth (FBW) of 14.3% has a 29.1-dB stopband rejection up to 15 <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">f</i> <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> (where <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">f</i> <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> stands for the passband center frequency). The fourth-order bandpass filter with an FBW of 10.8% demonstrates a 30.1-dB stopband rejection up to 12.1 <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">f</i> <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> . Both types of filters show compact sizes with low insertion losses less than 1.1 dB.
Spectral features due to on-board diffusers (2005)

The presence of structures, as observed in real spectral data from earth observing satellites, that are due to the on-board diffusers are discussed. The structures are shown to be caused by the speckles in the entrance slit of the spectrometer, created by the diffusers. A dedicated setup for the study of these spectral features will be presented together with results on different types of diffusers, i.e. surface diffusers and volume diffusers. Finally, methods to reduce the amplitude of the spectral features will be presented. It will be shown that QVD (quasi volume diffuser) and Spectralon (a volume diffuser) are far better in reducing the unwanted spectral features than an aluminum surface diffuser. Overall it can be stated that QVD is the "best" diffuser where the validity of this statement depends on the type of its use.
Spinning-Disk Interferometry: The BioCD (2004)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text David D. Nolte and Fred E. Regnier, "Spinning-Disk Interferometry: The BioCD," Optics & Photonics News 15(10), 48-53 (2004) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
3D Simulation for Melt Laser Anneal Integration in FinFET’s Contact (2020)

Process integration feasibility of UV nanosecond melt laser annealing (MLA) in 14 nm node generation FinFET's contact for dopant surface segregation and activation is assessed by using a 3D TCAD simulation tool. In a n-type source/drain (S/D) in-situ phosphorous doped epilayer, Sb ion implantation is performed, considering the advantage of its surface segregation in lowering of the contact resistivity. The simulation results show that the heat sources created by the laser irradiation are confined mainly in the replacement metal gate (RMG) part, suggesting a potential interest of controlling the polarization of laser light to enlarge the process window by reducing the laser absorption in the RMG part. Also, the estimated solidification front velocity (V) in the MLA-induced epilayer regrowth (~4 m/s) satisfies the requirements (~1 m/s <; V <; ~15 m/s) to enable the surface segregation and metastable activation of the dopants. The surface segregation is also experimentally confirmed in the FinFET contact module.