gebhart/patrepeval huggingface dataset:
Cooperative autonomous control for active power sharing in multi-terminal VSC-HVDC (2014)

Economical autonomous control for sharing active power among MTDC systems based on the availability of active power or on a power management policy is proposed in this paper. Power sharing among MTDC systems involves a priority or sequential procedural problem because of the use of the conventional droop strategy. On the other hand, the use of predefined or constant power sharing fails to identify the available power that can be shared when it is not consumed by another inverter. The proposed strategy addresses these issues through a variety of options. The test system presented in this paper consists of three simulated VSC terminals based on a detailed switching VSC model with two AC voltage levels. The MTDC system has been simulated in a PSCAD/EMTDC environment. The simulation results show a significant decrease in operating costs as well as the ability to provide effective protection with respect to the problem of overloading.
Configurable MCPW based inductor for mm-wave circuits and systems (2010)

High quality factor configurable inductors are critical components for robust multiband wireless applications. Configurable Multilayer Coplanar Wave Guide (MCPW) based inductors in nano-scale CMOS technologies are proposed in this paper for millimeter wave frequency applications. Inductors are tweaked by adjusting the transmission line length to compensate for process variations of the mm-wave circuits and cover multiple bands. For demonstration, a mm-wave Voltage Controlled Oscillator (VCO) using the configurable inductor was designed and fabricated. Measurement reveals that the VCO covers frequency ranging from 72.8 to 77.6 GHz with phase noise of -109 dBc/Hz at 10 MHz offset, which is in good agreement with the MCPW-based inductor model prediction.
Near-Surface Characterization Using Simultaneous Joint Inversion of Refracted and Surface Waves – A Case Study (2014)

Summary Near-surface characterization is an essential step of seismic processing, in particular for land data. Information on the shallow portion of the subsurface is usually extracted from the travel-time of the first arrivals, producing a compressional velocity (Vp) model by means of a tomographic process. In addition, an independent and robust source of information is represented nowadays by the surface waves, which can be exploited for estimating a high resolution shear velocity (Vs) model of the shallow layers. These two independent source of information are very appealing for an integrated approach, which can help in reducing the uncertainties associated with the near-surface model building. The Simultaneous Joint Inversion (SJI) framework is a quantitative integration scheme, where the two geophysical measurements are taken into account in a single minimization problem, whose output is a velocity model that honors the data of both the domains and the mutual consistency of Vp and Vs. The SJI of refracted waves and surface waves is particularly appealing for complex geological settings, where outperforms the industry standard, as demonstrated in this paper with a field example from the Middle East.
Acute effects of the use of a biofeedback system for the technical training in breaststroke swimming (2006)

The purpose of this research was to develop, validate, and evaluate a biofeedback system for the technical training in breaststroke swimming. The system lied on the assessment of speed fluctuation curves of an anatomical landmark of the swimmer(hip).
Optimising for Scale in Globally Multiply-Linked Gravitational Point Set Registration Leads to Singularities (2019)

The recently introduced gravitational point set registration methods can robustly align point sets with high noise ratios. While many results with rotation and translation resolution have been presented in the literature so far, the uncertainty about the scale resolving capability of globally multiply-linked gravitational point set registration methods is remaining. To address the uncertainty, we analyse the gravitational potential energy (GPE) functional of the system with two point sets with multivariate calculus and come to the conclusion that GPE of a singularity, i.e., the state when the template collapses to a single point, always has a lower energy than the state of the optimal alignment. Moreover, the GPE as a function of scale monotonically increases and does not have equienergetic states, which we prove for several hollow and volumetric geometric primitives in R 2 and R 3 including a unit circle, a unit sphere, a unit disk and a unit ball. We perform a series of experiments with various regular shapes and different combinations of references and templates to validate our findings. The consequence is that in practice, it is highly unlikely for globally multiply-linked gravitational alignment to resolve the scale accurately. We propose ways to overcome the limitation in scale resolution, which can be considered in the next generation of gravitational approaches.
A 2Gb/s point-to-point heterogeneous voltage capable DRAM interface for capacity-scalable memory subsystems (2004)

We describe a DRAM interface operating at 2Gb/s/pin. It utilizes simultaneous bidirectional signaling in a daisy-chained, point-to-point configuration to enable scalable memory subsystems, and also provides direct attach capability for logic devices. We present results from a system using both logic and DRAM test-chips.
Attentional blink in global versus local attentional modes (1998)

This pattern of results is consistent with the hypothesis that global attention mechanisms receive predominantly M-pathway input.
High-aspect Ration Ablation Using Plasma-induced Bubble Generator (2016)

For the present study, plasma-induced bubble generator with abrasive grain is proposed to obtain high aspect ratio hole processing. Previously our group has been invented plasma-induced bubble generator which can process wide range of material including conductive and non-conductive material and hard material such as carbon fiber. However there is certain limitation of aspect ratio of processed hole. Current study did evaluation of ability of processing in terms of conductivity of machining fluid and temperature concentration. Also, abrasive grain is introduced to accelerate the ability of processing with machining guide. This study contributes to achieve novel low-cost and high aspect ratio processing machine to process wide range of materials such as biological material to hard metal.
Treatment and Prevention of Intravascular Coagulation with Antiserum to Endotoxin (1973)

Because of the limited success of antibiotics, we have turned to antiserum against endotoxin to prevent one of the most devastating effects of gram-negative bacteremia: disseminated intravascular coagulation (generalized Shwartzman reaction). This reaction was produced in rabbits by iv injection of endotoxin at 24-hr intervals. Rabbit antiserum to endotoxin injected iv 2 hr before the second dose of endotoxin (treatment of disseminated intravascular coagulation) or 96 hr before the first dose (prevention) decreased the reaction from 90% to 18%. Intravascular coagulation was also prevented by antiserum to both heterologous bacteria and side-chain-deficient mutants, by the 19S immunoglobulins of antisera, and by hyperimmune globulin treated with mercaptoethanol and iodoacetate. Passive protection lasted for at least 30 days. Antiserum prevented the precipitous drop in fibrinogen and platelets that accompanies deposition of fibrin in the glomerulus and elsewhere. These findings indicate that protection by antiserum is independent of antibody to O antigen, does not require complement, and prevents the coagulation disturbances induced by endotoxin.
Autologous bilayered self-assembled skin substitutes (SASSs) as permanent grafts: a case series of 14 severely burned patients indicating clinical effectiveness (2018)

Split-thickness skin autografts (AGs) are the standard surgical treatment for severe burn injuries. However, the treatment of patients with substantial skin loss is limited by the availability of donor sites for skin harvesting. As an alternative to skin autografts, our research group developed autologous self-assembled skin substitutes (SASSs), allowing the replacement of both dermis and epidermis in a single surgical procedure. The aim of the study was to assess the clinical outcome of the SASSs as a permanent coverage for full-thickness burn wounds. Patients were recruited through the Health Canada's Special Access Program. SASSs were grafted on debrided full-thickness wounds according to similar protocols used for AGs. The graft-take and the persistence of the SASS epithelium over time were evaluated. 14 patients received surgical care with SASSs. The mean percentage of the SASS graft-take was 98 % (standard deviation = 5) at 5 to 7 d after surgery. SASS integrity persisted over time (average follow-up time: 3.2 years), without noticeable deficiency in epidermal regeneration. Assessment of scar quality (skin elasticity, erythema, thickness) was performed on a subset of patients. Non-homogeneous pigmentation was noticed in several patients. These results indicated that the SASS allowed the successful coverage of full-thickness burns given its high graft-take, aesthetic outcome equivalent to autografting and the promotion of long-term tissue regeneration. When skin donor sites are in short supply, SASSs could be a valuable alternative to treat patients with full-thickness burns covering more than 50 % of their total body surface area.
Transport and retention of colloidal tracers in regional lymphoscintigraphy in melanoma: influence on lymphatic mapping and sentinel node biopsy (1998)

Sentinel node (SN) biopsy is a staging technique used to select patients for regional lymphadenectomy in melanoma. We compared the two most widely used radioactive tracers, 99mTc-colloidal albumin (99mTc-CA) and 99mTc-sulphur colloid (99mTc-SC), with respect to scintigraphy, success rate in gamma probe guided biopsy and absolute uptake in the SN. Scintigraphy was performed in six volunteers after simultaneous injection of the respective tracers in each leg. Comparison of uptake of both tracers showed a higher uptake on the 99mTc-CA side. The scintigraphic count ratio of SNs labelled with 99mTc-SC compared with 99mTc-CA was 1 to 9 28. Next, 20 patients with biopsy-proven melanoma were randomized for injection of 99mTc-CA or 99mTc-SC followed by SN biopsy. Within 20 min after the injection, focal uptake was seen in all cases of the 99mTc-CA group but in only seven of the 10 patients in the 99mTc-SC group (P < 0.05). Focal accumulations were seen in all patients of both groups after 2 h. Spill to non-SNs was seen in five of the 99mTc-CA patients and three of the 99mTc-SC patients. In all patients the SNs could be retrieved under the guidance of a gamma probe and blue dye. The uptake in the SN was significantly higher (P < 0.001) after the injection of 99mTc-CA (0.92+/-0.40%) compared with 99mTc-SC (0.34+/-0.34%). When dynamic scintigraphy is performed, 99mTc-CA is preferable. SN uptake of 99mTc-SC is less than that of 99mTc-CA but this does not adversely affect the surgical procedure.
SERPINB3, Adult-Onset Immunodeficiency, and Generalized Pustular Psoriasis (2023)

Genetic variants in <i>SERPINB3</i> are associated with GPP and AOID with pustular skin reaction. The skin of patients with GPP and AOID carrying <i>SERPINB3</i> mutations showed overexpression of SERPINB3 and SERPINA1. Clinically and genetically, GPP and AOID appear to share pathogenetic mechanisms.
Impact of the Conjugation Method on the Immunogenicity of Streptococcus pneumoniae Serotype 19F Polysaccharide in Conjugate Vaccines (2010)

7vCRM (Pfizer, Inc.) and PHiD-CV (GlaxoSmithKline Biologicals) are two pneumococcal conjugate vaccines licensed for the prevention of invasive pneumococcal disease and acute otitis media caused by the vaccine serotypes of Streptococcus pneumoniae. Neither vaccine contains serotype 19A, but both contain the closely related serotype 19F. No decrease in the incidence of serotype 19A disease has been observed following the introduction of 7vCRM, suggesting that this serotype 19F-containing vaccine provides limited cross-protection against serotype 19A. To investigate the impact that conjugation methods may have on antipolysaccharide immune responses and to determine whether this limited cross-protection is characteristic of the serotype 19F polysaccharide or rather of the 19F-CRM (cross-reacting material) conjugate, we compared naturally induced antibodies against serotypes 19F and 19A with antibodies induced after vaccination with different pneumococcal conjugate vaccines. We found that conjugation of the serotype 19F polysaccharide using reductive amination (as in 7vCRM) resulted in the formation of at least one additional epitope that is not present in the native form of the 19F polysaccharide or following 19F conjugation using a bifunctional spacer (as in the prototype vaccine 7vOMPC) or cyanylation (as in PHiD-CV). We also found that pneumococcal vaccines conjugated using cyanylation induce more opsonophagocytic antibodies against serotype 19F and a considerably higher level of cross-opsonophagocytic antibodies against serotype 19A than vaccines conjugated using reductive amination. In conclusion, these results suggest that the conjugation method can influence the functionality of the antibodies induced against the homologous serotype 19F and the cross-reactive serotype 19A of S. pneumoniae.
Detecting hydrocarbons in carbonates: joint interpretation of CSEM and seismic (2010)

Quantitative interpretation (QI) of seismic data has been successfully used to predict reservoir properties such as porosity and fluid fill. In specific cases, however, adding resistivity estimates of the subsurface to the QI can reduce ambiguities in the properties prediction. Controlled‐ source electromagnetic (CSEM) sounding methods provide these estimates. By making use of their complementary nature, integration of seismic and electromagnetic datasets has been used to estimate the height of hydrocarbon‐ filled porous carbonate. In this paper, we present a methodology for joint interpretation, which can help us to discriminate tight carbonates from porous carbonates, and to differentiate between brine and hydrocarbon fill. When applied to a field in a carbonate setting, the estimated hydrocarbon column height corresponds qualitatively with the saturation height estimate based on production data.
Chapitre 2 : Les administrateurs du Parlement. Contribution à une sociologie des collaborateurs d’élus (2017)

La mission officielle des administrateurs du Parlement est d’assister les élus, quel que soit leur bord politique, dans l’exercice de leurs activités quotidiennes à Paris. Diplômés de Sciences Po Paris dans leur grande majorité mais ayant généralement échoué au concours de l’ENA, ces agents jouissent d’une position prestigieuse qu’ils cherchent à défendre en se présentant comme les gardiens du temple parlementaire. Cette position repose en particulier sur les mythes de la neutralité et de l’apolitisme que mettent systématiquement en avant les administrateurs. Nous montrons alors que des mécanismes de politisation fonctionnelle viennent brouiller les frontières entre administration et politique et que certains agents outrepassent leur simple rôle d’exécutant en affichant des préférences politiques dans le cadre de leur travail. Ce phénomène conduit le corps des administrateurs à développer des stratégies de sorties et de retour afin de préserver leur prestige et leur position face à d’autres types de collaborateurs.
Through-Space Charge Transfer and Nonlinear Optical Properties of Substituted Paracyclophane (2000)

The introduction, within a π-conjugated donor−acceptor molecule, of an intermediate barrier to electron tunneling and its size scaling and influence on electronic polarization properties have remained so far elusive issues of great potential interest toward the fine-tuning of the linear and nonlinear optical properties of molecular materials. Paracyclophane (pCP) provides a most relevant cornerstone for more elaborate compounds where donor and acceptor substituents are made to interact through a sterically constrained π−π stack. A first attempt in this direction is reported here with the synthesis of a model dipolar 4-(4-dihexylaminostyryl)-16-(4-nitrostyryl)[2.2]paracyclophane and the subsequent experimental and theoretical study of its quadratic nonlinear optical properties. A major outcome of this investigation is the evidence of a significant “through-space” charge transfer as unambiguously designated by the strong departure of the β quadratic hyperpolarizability tensor of the full doubly substituted molecule (60 × 10-30 esu) from the additive β value (18 × 10-30 esu) expected for strictly noninteracting singly substituted pCP moieties. This desired increase of nonlinear efficiency upon substitution is not offset by the usual red-shift of the absorption spectrum which generally curtails application perspectives in more common uninterrupted conjugated chains. The collective nonlinear polarization behavior involving the full end-to-end molecular structure is confirmed by theoretical calculations using the Collective Electron Oscillator (CEO) approach which furthermore indicates a significantly enhanced role of electron−hole pair delocalization in the higher order nonlinear response, compared to the linear polarizability or the static dipole moment.
An Intramolecular Cyclization Reaction Is Responsible for the in Vivo Inefficacy and Apparent pH Insensitive Hydrolysis Kinetics of Hydrazone Carboxylate Derivatives of Doxorubicin (2006)

Contradictory reports concerning the pH sensitive hydrolysis kinetics of certain hydrazone carboxylates of doxorubicin have appeared in this journal (Kaneko et al., Bioconjugate Chem. 1991, 2, 133. Padilla De Jesús et al., Bioconjugate Chem. 2002, 13, 453). Since the pH stability of the drug-carrier linkage in macromolecular prodrugs has a significant bearing on pharmacological efficacy, the hydrolysis kinetics of low molecular weight and polymeric doxorubicin hydrazone carboxylates were therefore reinvestigated. As observed previously, the conjugates readily release native doxorubicin at pH 5. Unexpectedly, in neutral buffer the hydrazone carboxylate conjugates do not release native doxorubicin, but instead rapidly release a doxorubicin derivative substituted at C-9 by 3,6-dihydro-1,3,4-oxadiazin-2-one with first-order kinetics (t(1/2) = 2.5 h). The proposed intramolecular cyclization reaction involving doxorubicin's C-14 hydroxyl and the carboxylate-substituted hydrazone rationalizes the seemingly anomalous hydrolysis kinetics seen for hydrazone carboxylate linked doxorubicin, and provides a possible explanation for the poor antitumor activity exhibited by polymer-doxorubicin conjugates utilizing this specific type of linkage.
Dynamics of bistable initially curved shallow microbeams: Effects of the electrostatic fringing fields (2014)

Effects of fringing electrostatic fields on the behavior of a double clamped initially curved microbeam are investigated. Galerkin's decomposition method is applied on the governing Euler-Bernoulli equation with distributed electrostatic force to obtain the lumped-parameter model of the system. The resulting single degree of freedom model is obtained with the Palmer's formula as a model for the fringing field effects. To derive an applied form of the fringing field effect in lumped model, we have used Genetic Algorithms as an optimization method. Then using the lumped model, we have investigated the system nonlinear dynamics. Comparison of the obtained bifurcation diagrams with the experimental results confirms that neglecting the fringing field effects results in a significant error which should be avoided for accurate molding purposes.
Regionality of disease progression predicts prognosis in amyotrophic lateral sclerosis (2015)

Amyotrophic lateral sclerosis (ALS) is a devastating neurological syndrome in which motor neurons degenerate relentlessly. Although the site of onset and the rate of spread have been studied extensively, little is known about whether focal as opposed to diffuse disease affects prognosis. We therefore tested the hypothesis that regionality of disease burden is a prognostic factor in ALS. We analysed clinical data from two large multicentre, longitudinal trials. Regionality was defined as the difference in progression rates in three domains as measured by the revised ALS Functional Rating Scale, omitting the respiratory domain from analysis. We used death by trial end as the outcome variable and tested this by logistic regression against predictor variables including regionality and overall rate of disease progression. There were 561 patients. Regionality of disease was independently associated with significantly higher chance of death by study end (odds ratio most diffuse against most focal category 0.354 (0.191, 0.657), p = 0.001), with a direct relationship between degree of regionality and odds of death. We have shown using clinical trial data that focal disease is associated with a worse prognosis in ALS. Measures of regionality warrant further independent consideration in the development of future prognostic models.
Deceased donor kidney transplantation across donor-specific antibody barriers: predictors of antibody-mediated rejection (2016)

IA-based desensitization failed to prevent ABMR in a considerable number of DSA+ recipients. Assessing DSA MFI may help stratify risk of rejection, supporting its use as a guide to organ allocation and individualized treatment.
A common framework for rate and distortion based scaling of highly scalable compressed video (1996)

Scalability refers to the ability to modify the resolution and/or bit rate associated with an already compressed data source in order to satisfy requirements which could not be foreseen at the time of compression. A number of researchers have already demonstrated the feasibility of efficient scalable image and video compression. The principle focus of this paper is to describe data structures for highly scalable compressed video, which are able to support simple, generic scaling approaches for both constant bit rate and constant distortion scaling criteria. Interactive video material presents particular challenges when the data stream is to be scaled to maintain an approximately constant level of distortion, rather than just a constant bit rate. Special attention is paid, therefore, to the development of generic, robust scaling algorithms for such applications. The data structures and scaling methodologies developed are particularly appealing for the distribution of highly scalable compressed video over heterogeneous media, because they simultaneously support both variable bit rate (VBR) and constant bit rate (CBR) services with a wide range of available service qualities, using only simple, generic mechanisms for scaling. The performance of the proposed scaling methodologies is experimentally investigated using a highly scalable video compression algorithm, which is able to achieve comparable compression performance to that of the inherently nonscalable MPEG-1 compression standard.
Rb4Sn5P4Se20: A Semimetallic Selenophosphate (2011)

Zwei Selenide wohnen, ach! in diesem Stoff: Die valenzpräzise Verbindung Rb4Sn5P4Se20 (siehe Bild; Rb blau, Sn grün, P schwarz, Se rot), das erste metallische Selenophosphat, stellt eine neue Hybridstruktur aus „leitfähigen“ [Sn5Se8]-Schichten und „isolierenden“ [P2Se6]-Liganden dar. Es hat die höchste elektrische Leitfähigkeit aller Chalkophosphate bei einer extrem niedrigen Wärmeleitfähigkeit von 0.44 W m−1 K−1 bei Raumtemperatur. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.