gebhart/patrepeval huggingface dataset:
New insight into high-field mobility enhancement of nitrided-oxide N-MOSFET's based on noise measurement (1994)

The mobility crossover phenomenon observed in NH/sub 3/-nitrided N-MOSFET's has been interpreted by the reduced acceptor-type interface states which are located near and above the conduction band edge. However. A direct confirmation of such a hypothesis is not available from the conventional electrical measurement techniques. In this work, for the first time, we used both 1/f noise and random telegraph signal (RTS) measurements which are capable of probing those oxide traps near and above Si conduction band of energy, to study the modification of interface traps induced by N/sub 2/O nitridation. The 1/f noise measurement results confirm that thermal nitridation decreases the near-interface oxide trap density at the higher energy levels, as a result, trapping of the mobile electrons is decreased. The RTS measurement further suggests that thermal nitridation moves the oxide traps farther away from the Si-SiO/sub 2/ interface and thus suppresses the Coulombic scattering of mobile electrons by the trapped charges. Both nitridation-induced interfacial modifications result in enhanced high-field mobility of nitrided-oxide devices over the standard MOS devices.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Facile Aqueous-Phase Synthesis of Bimetallic (AgPt, AgPd, and CuPt) and Trimetallic (AgCuPt) Nanoparticles (2020)

Multi-metallic nanoparticles continue to attract attention, due to their great potential in various applications. In this paper, we report a facile aqueous-phase synthesis for multi-metallic nanoparticles, including AgPt, AgPd, CuPt, and AgCuPt, by a co-reduction method within a short reaction time of 10 min. The atomic ratio of bimetallic nanoparticles was easily controlled by varying the ratio of each precursor. In addition, we found that AgCuPt trimetallic nanoparticles had a core-shell structure with an Ag core and CuPt shell.
Automated metabolic profiling of organic acids in human urine. II. Analysis of urine samples from "healthy" adults, sick children, and children with neuroblastoma. (1978)

Abstract Normalized median, minimum, and maximum values (analytical concentration factors) are given for 134 organic acids in urine of nine adult control subjects, five juvenile control subjects, and five children with neuroblastoma. The organic acids, separated by anion-exchange chromatography, were analyzed by a gas chromatograph-mass spectrometer-computer system. Sixty substances in this fraction are positively identified, and, of these, mean absolute concentrations are listed for 20. An additional 81 substances, sought but not found by this method, and 16 other substances found in a subset of these urines by another analytical method, are also listed. Measured retention indices on 5% OV-17 and a selected discriminating ion are given for each of the total of 231 compounds. Results are compared for the three groups of subjects, and the value of normalizing the data is discussed.
Allelic imbalance at the HER2/TOP2A locus in breast cancer (2015)

The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/2086062232155220.
MicroRNA-155 Confers Encephalogenic Potential to Th17 Cells by Promoting Effector Gene Expression (2013)

Th17 cells are central to the pathogenesis of autoimmune disease, and recently specific noncoding microRNAs have been shown to regulate their development. However, it remains unclear whether microRNAs are also involved in modulating Th17 cell effector functions. Consequently, we examined the role of miR-155 in differentiated Th17 cells during their induction of experimental autoimmune encephalomyelitis. Using adoptive transfer experiments, we found that highly purified, myelin oligodendrocyte glycoprotein Ag-specific Th17 cells lacking miR-155 were defective in their capacity to cause experimental autoimmune encephalomyelitis. Gene expression profiling of purified miR-155(-/-)IL-17F(+) Th17 cells identified a subset of effector genes that are dependent on miR-155 for their proper expression through a mechanism involving repression of the transcription factor Ets1. Among the genes reduced in the absence of miR-155 was IL-23R, resulting in miR-155(-/-) Th17 cells being hyporesponsive to IL-23. Taken together, our study demonstrates a critical role for miR-155 in Th17 cells as they unleash autoimmune inflammation and finds that this occurs through a signaling network involving miR-155, Ets1, and the clinically relevant IL-23-IL-23R pathway.
Abstract 2979: The effect of interferon gamma on melanoma progression under MAPK inhibitor therapy (2020)

Abstract About half of metastatic cutaneous melanoma harbor a mutation in the BRAF protein, causing constitutive activation of the MAPK pathway. Currently, patients with such mutation are treated with MAPK pathway inhibitors (MAPKi) targeting the mutant BRAF and its downstream MEK proteins. However, within a span of 6-12 months, these patients will relapse, and their tumors will acquire resistance to this treatment. In this project, we aim to understand the role of IFN gamma (IFNg) to help us determine if the resistance phenotype differs between cells exposed with MAPKi alone versus cells treated with MAPKi and IFNg. Previous literature has reported on the development of a dedifferentiated resistance phenotype which was characterized by a downregulation of MITF and an upregulation of AXL proteins. However, the patient-derived transcriptomic data comparing paired tumors pre- and post-MAPKi therapy did not show such changes in MITF or AXL levels. We posit that the discrepancy may be because most of the earlier studies on MAPKi resistance were done in vitro or immune-suppressed in vivo models. Melanoma biopsies from patients responding to MAPKi treatment showed a substantial increase in the tumor-infiltrating T cell and other immune cells. One of the most dominant immune factors produced by the T cells is the interferon gamma (IFNg). Intriguingly, our data show that IFNg, in the presence of MAPKi, can suppress the dedifferentiation switch that is induced by MAPKi-alone. Specifically, through serial western blots, we discovered that MAPKi and IFNg reduced the previously reported AXL upregulation and MITF downregulation in four different mutant BRAF melanoma lines. RNA sequencing from the same time points revealed that melanoma treated with MAPKi and IFNg upregulate IFN-stimulated genes that are typically expressed by immune cells; this leads us to believe that some novel transcriptomic programs have been activated by the combination of MAPKi and IFNg. By solely examining one immune factor, IFNg, we discovered one potential explanation for the discrepancy in the prevalence of MAPKi-induced dedifferentiation phenotype in the patient-derived melanoma samples. We are in the midst of performing drug screening experiments on MAPKi and IFNg-resistant melanoma lines in order to discover novel therapeutic vulnerabilities that were not observed with MAPKi-alone. Finally, by taking into account the secreted factors in the tumor microenvironment, our study can provide a more accurate depiction of MAPKi resistance evolution in mutant BRAF melanoma patients. Citation Format: Kevin Chen, Rachel McMillan, Mona Chatrizeh, Willy Hugo. The effect of interferon gamma on melanoma progression under MAPK inhibitor therapy [abstract]. In: Proceedings of the Annual Meeting of the American Association for Cancer Research 2020; 2020 Apr 27-28 and Jun 22-24. Philadelphia (PA): AACR; Cancer Res 2020;80(16 Suppl):Abstract nr 2979.
GEE, H. (ed.) 2000. Shaking the Tree. Readings from Nature in the History of Life. vii+411 pp. Chicago: University of Chicago Press. Price US $78.00, £55.00 (hard covers); US $27.50, £17.50 (paperback). ISBN 0 226 28496 4; 0 226 28497 2 (pb). (2001)

GEE, H. (ed.) 2000. Shaking the Tree. Readings from Nature in the History of Life. vii+411 pp. Chicago: University of Chicago Press. Price US $78.00, £55.00 (hard covers); US $27.50, £17.50 (paperback). ISBN 0 226 28496 4; 0 226 28497 2 (pb). - Volume 138 Issue 3
Electric arc furnace steel slag as a raw material towards the production of “green” cements (2011)

status: Published
Stark Deceleration of an Effusive Molecular Beam by a Single Semi-Gaussian Beam (2006)

We propose a novel scheme to decelerate a cw precooled molecular beam by using an optical Stark decelerator, which is composed of a red-detuned cw semi-Gaussian beam. The dynamical process of the optical Stark deceleration for a cw methane molecular beam is studied by Monte Carlo simulations. It is realized that the proposed optical Stark decelerator can be used to continuously slow a cw methane molecular beam with a longitudinal temperature of 30 mK, and a maximum reduction in the most probable speed of 0.388 m/s (corresponding to a relative change of 9.93%) can be obtained by using a single semi-Gaussian beam with a power of 500 W and a maximum central intensity of about 7.96×107 W/cm2.
New roles of the lymphatic endothelium in modulating adaptive immunity: implications for immune tolerance and cancer immunotherapy (2018)

Lymphatic vessels have traditionally been considered as passive conduits for interstitial fluid drainage and for immune cell trafficking to lymph nodes. In the last two decades, many studies have challenged this classical dogma: lymphatic endothelial cells (LECs) were shown to actively interact with immune cells by secreting chemokines and cytokines, and presenting antigens to T cells. These newly described functions pinpoint a multi-faceted role of LECs in orchestrating the immune response through both passive and active mechanisms. Yet, precise mechanisms leading to antigen-specific fine-tuning of the T cell response remain unexplored. Moreover, although lymphatics have been shown to play important roles in cancer, the contributions of LECs in regulating antitumor immunity have been largely overlooked by the biomedical community. This doctoral thesis aimed at filling these gaps. First, in order to investigate the mechanisms and implications of LEC antigen presentation to CD4+ T cells, we engineered a mouse model where LECs lacked the ability to present antigens to CD4+ T cells. In these mice, antigen-specific responses to vaccination were increased when compared to wild-type controls. Moreover, we demonstrated that LECs were poor inducers of CD4+ T cell activation in vitro, and that they could dampen CD4+ T cell activation by dendritic cells. Taken together, these findings suggest that LECs participate to the peripheral immune tolerance of CD4+ T cells. Second, we investigated the immunological consequences of the development of lymphatic vessels, called lymphangiogenesis, in mouse melanoma. Upon induction of tumor lymphangiogenesis, we observed striking tumor enrichment with immune cells, which resulted in a higher sensitivity of those tumors to immunotherapy. We subsequently demonstrated that inducing lymphangiogenesis in a mouse model of cold tumors, which lack immune infiltrates and do not respond to immunotherapies, could restore their responsiveness to immunotherapy treatments. Third, to predict which cancer types were the most likely to replicate the findings we obtained in mouse melanoma, we mined The Cancer Genome Atlas database for gene expression. We identified a set of cancers, such as colon adenocarcinoma and cholangiocarcinoma, where high expression of the lymphangiogenic growth factor was associated with a strong T cell signature. This doctoral thesis unveiled new immunomodulatory functions of LECs by which antigen-specific immune tolerance is induced. Additionally, it opened new avenues to target lymphatics therapeutically in cancer to potentiate immunotherapies. We believe this work contributes to demonstrating the immunological importance of LECs, and hope that lymphatics will be considered as an important immunomodulatory player of the tumor microenvironment when developing novel immunotherapies.
The Engineering Design of the 1.5 m Diameter Solenoid for the MICE RFCC Modules (2008)

The RF coupling coil (RFCC) module of MICE is where muons that have been cooled within the MICE absorber focus (AFC) modules are re-accelerated to their original longitudinal momentum. The RFCC module consists of four 201.25 MHz RF cavities in a 1.4 meter diameter vacuum vessel. The muons are kept within the RF cavities by the magnetic field generated by a superconducting coupling solenoid that goes around the RF cavities. The coupling solenoid will be cooled using a pair of 4 K pulse tube cooler that will generate 1.5 W of cooling at 4.2 K. The magnet will be powered using a 300 A two-quadrant power supply. This report describes the ICST engineering design of the coupling solenoid for MICE.
Insulin pump therapy for 1-6 year old children with type 1 diabetes. (2004)

For very young diabetic children, insulin pump therapy improves quality of life and is feasible and safe. It should be considered as an optional mode of therapy for this age group.
Qualitative and Quantitative Analysis of the Phenolic Constituents fromOrthosiphon aristatus (1991)

ORTHOSIPHON ARISTATUS (Orthosiphonis folium DAB 9) was studied with regard to its phenolic constituents. Twenty compounds were isolated and identified on the basis of their spectral characteristics. The compounds included nine lipophilic flavones, two flavonol glycosides, and nine caffeic acid derivatives. The presence of the recently reported methylripariochromene A could not be confirmed. All compounds identified were quantified by HPLC. The caffeic acid derivatives including the major compounds rosmarinic acid and 2,3-dicaffeoyltartaric acid (67% of total identified phenolics) predominated over the flavones (33%) in an aqueous MeOH extract. The predominance of the caffeic acid derivatives was even more pronounced in a hot water extract (94.5% of total identified phenolics) that was comparable to a herbal tea.
Maxillary reconstruction to enable implant insertion: a retrospective study of 181 patients (2008)

A guideline for surgical decision in the maxillary reconstruction for oral rehabilitation by implants may help to prevent failures of osseous resorption disorders and to foresee the investment of the bone in quality and necessary quantity.
<title>Effect of image stabilization on the performance of the MPEG-2 video coding algorithm</title> (1998)

The effect of image stabilization on the performance of the MPEG-2 video coding algorithm is investigated. It is shown that image stabilization prior to MPEG-2 coding of an unsteady image sequence does increase the quality of the compressed video considerably. The quality improvement is explained by fact that an actual zero motion vector is favored over a zero differential motion vector in the MPEG-2 video coding scheme. The bits saved in coding the motion information in P frames are then utilized in the coding of the DCT data in I frames. The temporal prediction of the macroblocks in P and B frames are also improved because of the increased quality of the compressed I frames and because an image stabilization algorithm can compensate for displacement with better than 1/2 pixel accuracy.
Fabrication of carbon nanotubes and byproducts by arc discharge in DC motors (2008)

Abstract The electrical arc generated between the brush and commutator of a DC motor is similar to the arc discharged between carbon electrodes. Since carbon nanotubes are produced by carbon electrode arc discharge, it is possible to produce carbon nanotubes and byproducts via the electrical arc generated between the brush and commutator of a DC motor. In this paper, we demonstrate experimentally that single‐wall carbon nanotubes and byproducts were generated on the surface of the brushes by the electrical arc of DC motors. The yield of the nanotubes was very low, and the nanotubes were of poor structural quality. If carbon nanotubes with a high electrical conductivity are produced across the segmented copper bars of the commutator, they can potentially cause the DC motor to flashover. Our experimental findings reveal that these carbon nanotubes and byproducts have no effect on the flashover of DC motors because they are extremely small and occur in small quantities. Copyright © 2008 Institute of Electrical Engineers of Japan. Published by John Wiley &amp; Sons, Inc.
Physico-Chemical Modifications and Biological Improvements of Biomedical PET as a Consequence of Excimer LASER Irradiation (2005)

LASER Excimer irradiation can modify surface properties for biocompatibility improvement of a medical device. The PETs from 3 different origins were used in this study. The samples have been irradiated by excimer LASER with 10 different energies. The surface profile, the surface energy and the materials crystallinity have been assessed. Biological characterizations were made with human embryonic epithelial cells L132: proliferation, vitality, viability, adhesion with the p-NPP, and morphology. - The profile measurements allowed to establish the ablation threshold, which was 36 mJ/cm². The surface hydrophilic state increased reciprocally with the irradiation intensity. The gain is 13 %. The irradiated and non-irradiated product has identical cristallinity. PET was shown not to be toxic for L132 cells. Cell proliferation and cell vitality showed dose-dependant increases reciprocal to the irradiation energy (from 88 to 138% with respect to control). The correlation was highly significant (R² = 0,8). SEM micrographs show that the cells are better spread on the surface of irradiated PET than on untreated PET.
Current implant surface technology: an examination of their nanostructure and their influence on fibroblast alignment and biocompatibility. (2009)

We assessed commonly available silicone implants and offer a unique overview into their surface topographies and how they are manufactured. We conclude that these surfaces require modernization. Our findings provide further insight into potential interactions between cellular assemblies and artificial surfaces and may contribute to the development of improved implant surfaces.
A Preliminary Analysis of the Oils ofArtemisia edgeworthiiBalak. andArtemisia parvifloraHam. ex D. Don (1992)

ABSTRACT The oils of Artemisia edgeworthii and A. parviflora were examined by GC and GC/MS. Only 37.92% and 22.12% of the oils were characterized with six components being common to both oils. KEYWORD INDEX: Artemisia edgeworthii Artemisia parviflora Asteraceaeessential oil composition
B/W adaptive image grabber with analog motion vector estimator at 0.3 GOPS (2002)

The chip contains a B/W CMOS adaptive video-camera providing quarter common interface format (176/spl times/144 pels), two analog memories, a motion estimator (ME), and a small controller to synchronize computational phases. A modified scheme uses the two analog memories to compare consecutive frames. Good speed and power performance is obtained with only 0.5 dB loss in S/N ratio. A H261-compatible bit stream can be produced to interface with H261 decoders.
Trauma, and Genital and Urethral Reconstruction (2022)

No AccessJournal of UrologyUrological Survey1 Feb 2023Trauma, and Genital and Urethral Reconstruction Sean P. ElliottMD, MS Sean P. ElliottSean P. Elliott More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003066AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail © 2022 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue 2February 2023Page: 436-438 Advertisement Copyright & Permissions© 2022 by American Urological Association Education and Research, Inc.MetricsAuthor Information Sean P. Elliott More articles by this author Expand All Advertisement PDF downloadLoading ...
Ehrlichia-Infected Ticks on Migrating Birds (2001)

Abstract During the spring of 1996, an estimated 581,395 Ehrlichia-infected ticks were imported into Sweden by migrating birds. Ehrlichia gene sequences found in ticks collected from these migrating birds were identical to those of granulocytic ehrlichiosis found in domestic animals and humans in Sweden. These findings support the idea that birds may play a role in dispersing Ehrlichia.
Learning individual roles from video in a smart home (2006)

This paper addresses learning and recognition of individual roles from video data in a smart home environment. The proposed approach is part of a framework for acquiring a high-level contextual model for human behaviour in an intelligent environment. The proposed methods for role learning and recognition are based on Bayesian models. The input is the targets and their properties generated and tracked by a robust video tracking system in the environment. The output is the roles "walking", "standing", "sitting", "interacting with table", "sleeping" for each target. A Bayesian classifier produced good results for a framewise classification of these roles, while a hidden Markov model had even better performance taking into account a priori probabilities of roles and role transitions. A support vector machine produced best classification results. The classifiers had, however, problems to distinguish ambiguous roles like "walking" and "standing" in the environment. The obtained results permit to pass to the next step in future work: learning and recognizing relations and situation. (9 pages)
Lighting-Effects Classification in Facial Images Using Wavelet Packets Transform (2003)

Faces often produce inconsistent features under different lighting conditions. Classifying lighting effects within a face image is therefore the first crucial step of building a lighting invariant face recognition system. This paper presents a hybrid system to classify face images based on the lighting effects present in the image. The theories of multivariate discriminant analysis and wavelet packets transform are utilised to develop the proposed system. An extensive set of face images of different poses, illuminated from different angles, are used to train the system. The performance of the proposed system is evaluated by conducting experiments on different test sets and by comparing its results against those of some existing counterparts.
Fabrication of silicon nanopillars containing polycrystalline silicon/insulator multilayer structures (1997)

A new approach to three-dimensional nanostructures is discussed with the goal of fabricating vertical, ultrasmall tunneling junctions suitable for single electron devices. Pillars consisting of multiple layers of polycrystalline silicon (polysilicon) (∼10 nm thick) and silicon nitride (∼2 nm thick) were laterally oxidized. The fabrication of vertically stacked silicon nanoislands, with dimensions on the order of 10 nm in all three directions, connected by thin silicon nitride layers, is demonstrated. The saturation of the polysilicon core diameter during the lateral pillar oxidation process is clearly observed, confirming the self-limiting effect for polysilicon pillars. This approach allows the fabrication of three-dimensional nanostructures using conventional silicon processing equipment.
In vivo enhancing effect of Propionibacteria on the growth of fecal Bifidobacteria. Relationship with colonic transit time (1998)

of Acacia gum polymers (GA) on both human fecal flora composition and metabolism in vitro.Methods: GA, together with short chain fructo-oligosaccharides (FOS), were incu- bated with human fecal bacteria in a continuous fermentor for 10 days.The cul- ture was operated at 0.1 h-1 dilution rate, under an anaerobic atmosphere and the pH was controlled at 6.5.After eight bac- terial population turn-overs, the short- chain fatty acids (SCFA) concentrations