gebhart/patrepeval huggingface dataset:
ALLETHRIN. RESOLUTION OF dl-ALLETHROLONE AND SYNTHESIS OF THE FOUR OPTICAL ISOMERS OF trans-ALLETHRIN (1954)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTALLETHRIN. RESOLUTION OF dl-ALLETHROLONE AND SYNTHESIS OF THE FOUR OPTICAL ISOMERS OF trans-ALLETHRINF. B. LaFORGE, NATHAN GREEN, and M. S. SCHECHTERCite this: J. Org. Chem. 1954, 19, 3, 457–462Publication Date (Print):March 1, 1954Publication History Published online1 May 2002Published inissue 1 March 1954https://pubs.acs.org/doi/10.1021/jo01368a027https://doi.org/10.1021/jo01368a027research-articleACS PublicationsRequest reuse permissionsArticle Views141Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Information measures, effective complexity, and total information (1996)

This article defines the concept of an information measure and shows how common information measures such as entropy, Shannon information, and algorithmic information content can be combined to solve problems of characterization, inference, and learning for complex systems. Particularly useful quantities are the effective complexity, which is roughly the length of a compact description of the identified regularities of an entity, and total information, which is effective complexity plus an entropy term that measures the information required to describe the random aspects of the entity. Mathematical definitions are given for both quantities and some applications are discussed. In particular, it is pointed out that if one compares different sets of identified regularities of an entity, the ‘best’ set minimizes the total information, and then, subject to that constraint, minimizes the effective complexity; the resulting effective complexity is then in many respects independent of the observer. © 1996 John Wiley & Sons, Inc.
Security Management Architecture for NFV/SDN-Aware IoT Systems (2019)

The Internet of Things (IoT) brings a multidisciplinary revolution in several application areas. However, security and privacy concerns are undermining a reliable and resilient broad-scale deployment of IoT-enabled critical infrastructures (IoT-CIs). To fill this gap, this paper proposes a comprehensive architectural design that captures the main security and privacy challenges related to cyber-physical systems and IoT-CIs. The architecture is devised to empower IoT systems and networks to make autonomous security decisions through the usage of novel technologies such as software defined networking and network function virtualization, as well as endowing them with intelligent and dynamic security reaction capabilities by relying on monitoring methodologies and cyber-situational tools. The architecture has been successfully implemented and evaluated in the scope of ANASTACIA H2020 EU research project.
Design of a Quadramanual Robot for Single-Nostril Skull Base Surgery (2012)

Innovations in the field of continuum robotics are enabling increasingly thin and dexterous slave robots in surgical telemanipulation systems. Actuation of these robots is a challenge, because many degrees of freedom must be controlled simultaneously in a compact and unobtrusive package in the operating room. While significant progress in designing these actuation units has been made for both larger, non-medical continuum robots, and for certain types of surgical continuum robots, the design of clinically-relevant actuation units for concentric tube robots is a comparatively understudied area of research. To address this, in this paper we present the design of a robot intended to deliver four concentric tube manipulators simultaneously through a single nostril. We present the considerations that motivated the design and the prototype we have constructed to meet these needs.
Enzymes That Hydrolyze Fungal Cell Wall Polysaccharides (1971)

Abstract A specific fungal α-(1 → 4)-glucanase, mycodextranase, useful for the large scale production of nigerose, has been purified to homogeneity in high yield from the culture filtrate of Penicillium melinii QM 1931. It has been resolved into fast and slow forms; designations based on their differing electrophoretic mobilities at pH 4.5. The fast form constitutes about 85% of the protein and enzymatic activity. Both forms hydrolyze the glucan nigeran (mycodextran) and certain oligosaccharides of nigeran yielding nigerose and the tetrasaccharide, O-α-d-glucopyranosyl-(1 → 3)-O-α-d-glucopyranosyl-(1 → 4)-O-α-d-glucopyranosyl-(1 → 3)-d-glucose, as sole end products. Glucose is not produced. Sedimentation equilibrium studies indicate that fast and slow enzymes both have molecular weights of 40,000 ± 2,000 daltons. They have similar but not identical amino acid compositions both being rich in serine, threonine, glutamic and aspartic acids, but have a low content of cysteine and tryptophan. Both mycodextranases contain associated carbohydrate. The ultraviolet absorption spectra, urea sensitivities, and pH activity profiles for both forms are practically identical. In addition both forms display maximum catalytic activities at 70° and are fully active in 40% dimethyl sulfoxide. Of a number of general enzyme inhibitors tested, only Ag+, Hg+, N-chlorosuccinimide, and N-bromosuccinimide inactivated the fast enzyme. Some aspects of the action pattern and mechanism of the fast form have been examined in detail. It operates via an endo-multichain mechanism; both end products are formed at a constant rate during hydrolysis but nigerose does not arise from tetrasaccharide. Competitive inhibition studies show that the fast enzyme preferentially binds oligosaccharides with alternating α-(1 → 3)- and α-(1 → 4)-glucosidic linkages, and experiments with certain oligosaccharides of nigeran give results consistent with a model in which the substrate-binding site holds 8 glucopyranose units with a catalytic site located midway in this site. The enzyme has been used to study the fine structure of nigeran and the general structure of isolichenin. In the former case this has been done by identifying and quantitating the linkages present at its reducing and nonreducing termini. The data obtained are used to postulate a general mechanism for the biosynthesis of nigeran.
Production of a Chimeric Form of CD23 That Is Oligomeric and Blocks IgE Binding to the FcεRI (1998)

Abstract The low affinity receptor for IgE (FcεRII/CD23) has previously been shown to interact with IgE with a dual affinity. Three chimeric constructs were created containing the lectin domain (amino acids 172–188) or the “neck” and lectin domain (amino acids 157–188) attached to subunits of oligomeric proteins. All chimeras were incapable of interacting with IgE with either a high or low affinity, indicating that the α-helical stalk of CD23 is important for orienting the lectin heads such that an interaction with IgE can occur. This concept received further support in that a chimeric CD23 composed of the human CD23 stalk and the mouse CD23 lectin head bound mouse IgE with a dual affinity, but could only bind rat IgE with a low affinity. Effort was next concentrated on a construct consisting of the entire extracellular (EC) region of CD23. A mutation to the first cleavage site of CD23 (C1M) resulted in a more stable molecule as determined by a decrease of soluble CD23 release. A soluble chimeric EC-C1M was prepared by attaching an isoleucine zipper to the amino terminus (lzEC-C1M). The interaction with IgE by lzEC-C1M was found to be superior to that seen with EC-CD23. The lzEC-C1M could inhibit binding of IgE to both CD23 and the high affinity receptor for IgE, FcεRI, providing further evidence for a strong interaction with IgE. FcεRI inhibition (∼70%) was seen at equimolar concentrations of lzEC-C1M, implying the effectiveness of this chimera and suggesting its potential therapeutic value.
A CMOS analog continuous-time delay line with adaptive delay-time control (1988)

A CMOS analog continuous-time delay line composed of cascaded first-order current-domain all-pass sections is discussed. Each all-pass section consists of CMOS transistors and a single capacitor. The operation is based on the square-law characteristic of an MOS transistor in saturation. The delay time per section can either be controlled by an external voltage or locked to an external reference frequency by means of a control system which features a large capture range. Experimental verification has been performed on two setups: an integrated cascade of 26 identical all-pass sections and a frequency-locking system breadboard built around two identical on-chip all-pass sections.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Measurement of the multi-photon absorption and nonlinear refraction spectra in PTS from 800 to 1600 nm (1994)

Since the first measurements of large nonlinear optical coefficients in π-electron conjugated systems, such materials have been studied for all-optical applications. Single crystal PTS seems to offer a very large n2. Often, however, associated with a large n2 is strong two photon absorption, which can limit a material's usefulness for all-optical devices. We report the first picosecond pulse, tunable, multi-photon absorption coefficient and nonlinear refraction measurements on single crystal samples of PTS. The complete spectra yield the two photon resonances obtained from near-resonant to off-resonant conditions. The resonant structure, in turn, reveals the locations of the two-photon states and unveils spectral regions where the two-photon figure of merit, T, may be suitable for all-optical switching. The two photon absorption coefficient measurements were conducted using the Z-scan method with two different systems. The measurements using the 65-ps system indicated the presence of a very strong resonance at 900 nm. In addition three more resonances were identified above 1000 nm: at 1200, 1400, and 1550 nm, with the resonance at 1200 nm being strongest. The presence of the two photon state near 1400 nm confirmed the resonance implied from previous third harmonic generation experiments. The locations of the identified, multiphoton states, with respect to the excitonic peak, are shown in Fig. 2. The resonance at 1200 nm indicates a strong two-photon state located slightly above the excitonic peak. The resonances at 1400 nm and 1550 nm represent two weaker states well below the single-photon state. Finally, a nonresonant measurement was performed at 1600 nm which gave a two photon absorption coefficient of no more than 0.2 cm/GW and a n2 = 1.5(±0.3) × 10-12 cm2/W, giving a T of 0.04. The two photon absorption and nonlinear refractive index spectra, particularly when combined via the figure of merit, T, reveal the spectral regions in PTS where all-optical devices may work, as shown in Fig. 3. Near 1350 nm, T approaches 1, indicating a useful region of the spectra. T drops significantly below 1 around 1470 nm and again beyond 1580 nm offering the possibility for all-optical devices in these regions.
P1706Stability and instability of mechanisms at sites where ablation terminates persistent atrial fibrillation prior to pulmonary vein isolation (2017)

Purpose: We aimed to investigate the levels of circulating adiponectin and of the inflammatory markers high sensitivity C-reactive protein and interleukin-6 in AF and controls, and their possible relations to EAT thickness.Methods: We studied prospectively 103 patients with AF, divided into 2 subgroups, of paroxysmal and permanent AF and 81 controls, in sinus rhythm.EAT and left atrial size were assessed by echocardiography.Quantitative immunoassay techniques with use of specific monoclonal antibody for serum adiponectin were used for evaluation of adiponectin and inflammatory biomarkers.Biochemical and echocardiographic characteristics of the study patients are presented in Table 1.Results: Levels of circulating adiponectin, high sensitivity C-reactive protein and interleukin-6 were significantly increased in AF groups compared to controls (p<0.01).Adiponectin was inversely related to EAT size (R¼0.2,p¼0.003).All inflammatory markers were positively related to left atrial volume (R¼0.5, p<0.0001 for interleukin, R¼0.2, p¼0.02 for high sensitivity-C reactive protein, and R¼0.2, p¼0.003 for adiponectin respectively).Conclusion: Increased adiponectin levels in AF may reflect disconnection of the hormone from its receptors, or alternatively a reactive increase to the arrhythmia process.The inverse relation of elevated adiponectin to EAT and the direct association of inflammatory markers to left atrial size suggest a role of epicardial fat and inflammation in the remodeling process.
Current Status of IPv6 Management (2002)

Nowadays, we are at an important time of the development of the IPv6 (Internet Protocol version 6) network. Until now, this protocol was used only between IPv6 «islands». These islands were connected by IPv4 (Internet Protocol version 4) networks. So the transport of IPv6 packets was made through IPv4 ones, or into MPLS (MultiProtocol Label Switching) tunnels. Now, that real IPv6 native equipment appears, it is possible to create real native IPv6 networks.Because in these networks, IPv4 does not exist, a new challenge for IPv6 network management emerges, because, until now, most of the IPv6 management architecture were defined upon IPv4, with SNMP (Simple Network Management Protocol) over IPv4 asking for the few MIBs (Management Information Bases) able to manage IPv6 networks. Now that IPv6 networks become IPv6 protocol only, how can we manage them ?The purpose of this report is to provide a state of the art description of what can be used to manage IPv6 native networks and what is really used today.
A CASE OF INCARCERATED FEMORAL HERNIA ASSOCIATED WITH POLYCYTHEMIA VERA (1994)

An operative case of incrcerated femoral hernia associated with polycythemia vera (PV) is herein reported. A 76-year-old woman, who had been treated for PV with busulfan over the previous 7 years, developed an incarcerated femoral hernia and underwent partial resection of the small intestine along with herniorrhaphy under general anesthesia. The patient had been associated with severe bradycardia and malnutrition preoperatively, and also showed some mild respiratory failure postoperatively. However, the postoperative course was otherwise uneventful with no symptoms of disseminated intravascular coagulopathy or thrombosis, while prescribing a temporary pacemaker and intravenous administration of ulinastatin. The patient was discharged on the 15th postoperative day in good condition. Fifteen surgical cases of PV, including this case, have been reported in Japan and most of them were frequently accompanied with postoperative complications, which sometimes were fatal. Careful postoperative management of bleeding and any thrombotic complications therefore seems to be essential in successful management of the postoperative course in patients with polycythemia vera.
Gaussian Processes for Survival Analysis (2016)

We introduce a semi-parametric Bayesian model for survival analysis. The model is centred on a parametric baseline hazard, and uses a Gaussian process to model variations away from it nonparametrically, as well as dependence on covariates. As opposed to many other methods in survival analysis, our framework does not impose unnecessary constraints in the hazard rate or in the survival function. Furthermore, our model handles left, right and interval censoring mechanisms common in survival analysis. We propose a MCMC algorithm to perform inference and an approximation scheme based on random Fourier features to make computations faster. We report experimental results on synthetic and real data, showing that our model performs better than competing models such as Cox proportional hazards, ANOVA-DDP and random survival forests.
Automated image registration of gated cardiac single‐photon emission computed tomography and magnetic resonance imaging (2004)

Automatic registration of gated MPS and cine MRI is possible with the use of a mutual information-based technique when MR images are presegmented. Cardiac motion can be used to isolate the left ventricle (LV) on the MR images automatically, and subsequently the segmented MR images can be coregistered with gated MPS.
ChemInform Abstract: Nucleosides and Nucleotides. Part 115. Synthesis of 3‐Alkyl‐3‐deazainosines via Palladium‐Catalyzed Intramolecular Cyclization: A New Conformational Lock with the Alkyl Group at the 3‐Position of the 3‐Deazainosine in anti‐Conformation. (1993)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A heuristic algorithm to find the best tree-structured image decomposition (2004)

In the context of uniform filter bank, width of the hand depends upon the order of the subband decomposition, however for non-uniform filter banks there exist infinite possibilities even when the order is fixed. These infinite possibilities can be brought down to a certain number by using tree structured non-uniform decomposition of the spectrum, with a given pair of low pass and high pass filter. We address the problem of finding the decomposition that gives maximum coding gain. This question is extended to two dimensional signal like image. In this work we suggest a heuristic algorithm that avoids the exhaustive search of max coding gain. We consider separable filters. With the assumption of unit norm of each filter in filter pair.
Solid-Phase Synthesis of Peptidylphosphonates (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSolid-Phase Synthesis of PeptidylphosphonatesDavid A. Campbell and Jason C. BermakCite this: J. Am. Chem. Soc. 1994, 116, 13, 6039–6040Publication Date (Print):June 1, 1994Publication History Published online1 May 2002Published inissue 1 June 1994https://pubs.acs.org/doi/10.1021/ja00092a093https://doi.org/10.1021/ja00092a093research-articleACS PublicationsRequest reuse permissionsArticle Views230Altmetric-Citations43LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information Get e-Alerts
High-bit-rate quantum key distribution with entangled internal degrees of freedom of photons (2016)

Quantum communication over long distances is integral to information security and has been demonstrated in free space and fibre with two-dimensional polarisation states of light. Although increased bit rates can be achieved using high-dimensional encoding with spatial modes of light, the efficient detection of high-dimensional states remains a challenge to realise the full benefit of the increased state space. Here we exploit the entanglement between spatial modes and polarization to realise a four-dimensional quantum key distribution (QKD) protocol. We introduce a detection scheme which employs only static elements, allowing for the detection of all basis modes in a high-dimensional space deterministically. As a result we are able to realise the full potential of our high-dimensional state space, demonstrating efficient QKD at high secure key and sift rates, with the highest capacity-to-dimension reported to date. This work opens the possibility to increase the dimensionality of the state-space indefinitely while still maintaining deterministic detection and will be invaluable for long distance 'secure and fas' data transfer.
Oligomeric cyclization of dinitriles in the synthesis of phthalocyanines and related compounds: the role of the alkoxide anion (1987)

The formation of phthalocyanine from phthalonitrile has been shown to proceed through reactive precursors condensing to reactive oligomeric intermediates which, as a result of ring-closure reactions, cyclize to conjugated macrocyclic product. The roles of alkoxide anion in the reaction scheme leading to phthalocyanine has been illustrated by isolation of reactive precursor sodium 1-imido-3-methoxyisoindolene and reactive intermediate lithium 1-imido-3-(3-methoxy-5-nitroisoindolenin-1-ylideneamino)-5-nitroisoindole (6) while its role in the overall yield of desired conjugated macrocyclic product has been shown by comparing the yield of magnesium dibenzobarrelenoporphyrazine to that obtained when the alkoxide concentration was reduced during the synthesis.
Inhibition of low-density lipoprotein oxidation by the pure antiestrogens ICI 182780 and EM-652 (SCH 57068) (2002)

Both ICI 182780 and EM-652 exhibited potent antioxidant activity, which could have important biological implications.
Dynamic resource allocation for self-similar traffic in ATM network (1999)

In order to achieve efficient resource utilization in an ATM network, we present a dynamic resource allocation model for self-similar traffic that employs input traffic prediction and parameter estimation. The performance of the proposed model have been evaluated by mathematical analysis and simulations.
(AI-102)CALIFORNIA CHAPTER OF THE AMERICAN ACADEMY OF OPTOMETRY (2000)

Mintz, Dena M. OD; Twa, Michael D. OD; Faith, Steven E. OD; Bailey, Charles H. OD; Ota, Wesley T. OD; Greer, Robert OD
Speech dereverberation in noisy environments using an adaptive minimum mean square error estimator (2011)

The authors present here a novel method for reducing the late reverberation of speech signals in noisy environments. In this method, the amplitude of clean signal is obtained by an adaptive estimator that minimises the mean square error (MSE) under signal presence uncertainty. The spectral gain function, that is an adaptive variable-order minimum MSE estimator, is obtained as a weighted geometric mean of hypothetical gains associated with speech presence and absence. The order of estimator is estimated for each time frame and each frequency component individually. The authors propose the adaptation of order of estimator according to the probability of speech presence, which makes the estimation more accurate. The evaluations confirm superiority of the proposed method in dereverberation of speech signals in noisy environments.