gebhart/patrepeval huggingface dataset:
Reaction and Transport Processes Controlling In Situ Chemical Oxidation of DNAPLs (2006)

The first reported case of hereditary spherocytosis (HS) and glucose-6-phosphate dehydrogenase deficiency in a black is presented. The recent literature is reviewed, with emphasis on the frequency of multiple inherited RBC defects in this ethnic group. Despite a coexisting hemoglobinopathy or enzyme deficiency, HS can be diagnosed in most cases by the peripheral blood smear, osmotic fragility curve, and family history. The implications of the double RBC abnormality are discussed, stressing the importance of splenectomy in relieving the hemolytic component due to spherocytosis.
Subsite mapping of the binding region of α‐amylases with a computer program (2002)

A computer program has been evaluated for subsite map calculations of depolymerases. The program runs in windows and uses the experimentally determined bond cleavage frequencies (BCFs) for determination of the number of subsites, the position of the catalytic site and for calculation of subsite binding energies. The apparent free energy values were optimized by minimization of the differences of the measured and calculated BCF data. The program called suma (SUbsite Mapping of alpha-Amylases) is freely available for research and educational purposes via the Internet (E-mail: gyemant@tigris.klte.hu). The advantages of this program are demonstrated through alpha-amylases of different origin, e.g. porcine pancreatic alpha-amylase (PPA) studied in our laboratory, in addition to barley and rice alpha-amylases published in the literature. Results confirm the popular 'five subsite model' for PPA with three glycone and two aglycone binding sites. Calculations for barley alpha-amylase justify the '6 + 2 + (1) model' prediction. The binding area of barley alpha-amylase is composed of six glycone, two aglycone binding sites followed by a barrier subsite at the reducing end of the binding site. Calculations for rice alpha-amylase represent an entirely new map with a '(1) + 2 + 5 model', where '(1)' is a barrier subsite at the nonreducing end of the binding site and there are two glycone and five aglycone binding sites. The rice model may be reminiscent of the action of the bacterial maltogenic amylase, that is, suggesting an exo-mechanism for this enzyme.
Advanced Power Control Scheme in Wireless Power Transmission for Human Protection From EM Field (2015)

The wireless power transmission (WPT) system must guarantee human protection from the electromagnetic (EM) field around the system in proportion to the increase of the transmit power. This paper presents an advanced power control scheme to reduce the EM field. The basic operation of the proposed scheme is the automatic control of the transmit power according to the proximity of the human body within a certain distance from the WPT system. For the initial design, the EM field simulation is carried out using the HFSS 3-D EM simulator. The initial regions around the system are set up according to the EM field simulation results and the human exposure guideline of the 1998 International Commission on Non-Ionizing Radiation Protection (ICNIRP). A WPT system is designed and implemented using the magnetic resonance in order to measure the EM field and confirm the final scheme. The system is operated at 1.8-MHz band to charge a 24-V 40-Ah lead-acid battery embedded in a docent robot. A laser sensor is also used to detect the proximity of the human body. Two communication schemes are used for automatic wireless charging and power control scheme. By the EM field measurement results of the WPT system, the power control scheme is finally confirmed. The performance measurement with a final scheme shows that the EM field is adaptively reduced to less than the guideline value depending on the proximity of the human body.
Cancer of the Gallbladder in a 9-Year-Old Girl (1985)

Carcinoma of the gallbladder was found in a 9-year-old girl. The patient was transferred to our hospital because of an abdominal mass and right upper quadrant pain. X-ray cholecystography and ultrasonography were performed preoperatively. The ultrasonic scan showed a thickened wall and lack of contractility of the gallbladder. A laparotomy was performed under the diagnosis of chronic cholecystitis. At operation a peanut-sized nodule, in which adeno carcinoma was demonstrated by frozen section, was palpable at the neck of the gallbladder. Cholecystectomy was performed with T-tube drainage and postoperative chemotherapy was administered. The patient has had no evidence of tumour recurrence in 24 months of follow-up.
Performance of multihop wireless networks (2003)

Existing wireless ad hoc routing protocols typically find routes with the minimum hop-count. This paper presents experimental evidence from two wireless test-beds which shows that there are usually multiple minimum hop-count paths, many of which have poor throughput. As a result, minimum-hop-count routing often chooses routes that have significantly less capacity than the best paths that exist in the network. Much of the reason for this is that many of the radio links between nodes have loss rates low enough that the routing protocol is willing to use them, but high enough that much of the capacity is consumed by retransmissions. These observations suggest that more attention be paid to link quality when choosing ad hoc routes; the paper presents measured link characteristics likely to be useful in devising a better path quality metric.
Plasmonic nanoantennas for efficient control of polarization-entangled photon pairs (2012)

We suggest a source of polarization-entangled photon pairs based on a cross-shaped plasmonic nanoantenna driven by a single quantum dot. The integration of the nanoantenna with a metal mirror overcomes the fundamental tradeoff between the spontaneous emission (SE) enhancement and the extraction efficiency typical of microcavity- and nanowire-based architectures. With a very high extraction efficiency of entangled photons ($\ensuremath{\approx}$$90%$) at $1.55$ $\ensuremath{\mu}$m and large SE enhancement ($\ensuremath{\approx}$90) over a broad 330-nm spectral range, the proposed design will pave the way toward reliable integrated sources of nonclassical light.
Prevention of levodopa‐induced dyskinesias by a selective NR1A/2B N‐methyl‐D‐aspartate receptor antagonist in parkinsonian monkeys: Implication of preproenkephalin (2005)

Enkephalin is reported to play an important role in the pathophysiology of levodopa (LD) -induced dyskinesias. The present study investigated the effect of chronic treatment with a selective NR1A/2B N-methyl-D-aspartate (NMDA) receptor antagonist, CI-1041, on the expression of preproenkephalin-A (PPE-A) in brains of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) -treated monkeys in relation to the development of LD-induced dyskinesias. Four MPTP-monkeys received LD/benserazide alone; they all developed dyskinesias. Four other MPTP-monkeys received LD/benserazide plus CI-1041; only one of them developed mild dyskinesias at the end of the fourth week of treatment. Four normal monkeys and four saline-treated MPTP monkeys were also included. MPTP-treated monkeys had extensive and similar striatal dopamine denervation. An increase of PPE-A mRNA levels assayed by in situ hybridization was observed in the lateral putamen (rostral and caudal) and caudate nucleus (rostral) of saline-treated MPTP monkeys compared to controls, whereas no change or a small increase was observed in their medial parts. Striatal PPE-A mRNA levels remained elevated in LD-treated MPTP monkeys, whereas cotreatment with CI-1041 brought them back to control values. These findings suggest that chronic blockade of striatal NR1A/2B NMDA receptors with CI-1041 normalizes PPE-A mRNA expression and prevents the development of LD-induced dyskinesias in an animal model of Parkinson disease.
Kinetic Titration Series with Biolayer Interferometry (2014)

Biolayer interferometry is a method to analyze protein interactions in real-time. In this study, we illustrate the usefulness to quantitatively analyze high affinity protein ligand interactions employing a kinetic titration series for characterizing the interactions between two pairs of interaction patterns, in particular immunoglobulin G and protein G B1 as well as scFv IC16 and amyloid beta (1-42). Kinetic titration series are commonly used in surface plasmon resonance and involve sequential injections of analyte over a desired concentration range on a single ligand coated sensor chip without waiting for complete dissociation between the injections. We show that applying this method to biolayer interferometry is straightforward and i) circumvents problems in data evaluation caused by unavoidable sensor differences, ii) saves resources and iii) increases throughput if screening a multitude of different analyte/ligand combinations.
Ultimate fast optical switching of a planar microcavity in the telecom wavelength range (2011)

We have studied a GaAs–AlAs planar microcavity with a resonance near 1300 nm in the telecom range by ultrafast pump-probe reflectivity. By the judicious choice of pump frequency, we observe an ultimate fast and reversible decrease in the resonance frequency by more than half a linewidth due to the instantaneous electronic Kerr effect. The switch-on and switch-off of the cavity is only limited by the cavity storage time of τcav=0.3 ps and not by intrinsic material parameters. Our results pave the way to supraterahertz switching rates for on-chip data modulation and real-time cavity quantum electrodynamics.
Exploring the Costs of Higher Education: Priorities and Policies. (1997)

Record Type: Non-Journal Publication Date: 1997-Nov Pages: 35 Abstractor: N/A Reference Count: N/A ISBN: N/A ISSN: N/A Exploring the Costs of Higher Education: Priorities and Policies. Losco, Joseph; Fife, Brian L. This paper examines expenditure patterns at higher education institutions in recent years, in light of the spiraling cost of higher education. It utilizes data from the U.S. Department of Education's Integrated Postsecondary Education Data System (IPEDS), begun in 1986, and the Higher Education General Information Survey (HEGIS), which goes back to 1966. IPEDS and HEGIS figures demonstrated that instruction predictably accounts for the largest percentage of total spending. While spending increased in almost all categories between 1977 and 1994, increases were smallest in the traditional areas of instruction, library, and plant operations, and largest in ancillary services and administration. Instructional spending as a percentage of total expenditures fell at public universities, public four-year colleges, and private four-year colleges. Research spending as a percentage of total expenditures increased significantly at private and public universities. Comparing different types of institutions, the largest proportionate change from 1990-91 to 1994-95 was a decrease in mean instructional expenditures at Carnegie Classification Research I public universities of 5.9 percent. Three appendixes provide IPEDS variable descriptions, Carnegie Classification codes, and a list of Carnegie-classified doctoral institutions. (Contains 14 references, 17 tables of data, and 1 figure.)
Postdural Puncture Headaches in Special Patient Populations (1999)

In Response: We appreciate the comments by Miguel et al. regarding our report of postdural puncture headache (PDPH) and acute leukemia [1]. Although these authors describe a case of PDPH in an immunocompromised patient with human immunodeficiency virus, the headache was of longer duration compared with our patient's headache. Because many PDPHs resolve within 2 wk [2], and our patient's headache resolved within the expected time period, we chose non-invasive treatment. We agree that dextran-40 is another nonblood alternative to autologous epidural blood patch. Although a preliminary study identified epidurally administered dextran-40 as a safe and effective nonblood alternative [3], the neurologic effects of dextran-40 are unknown. In addition, there is a small but definite risk of anaphylaxis after dextran-40 administration [4]. Brenda A. Bucklin, MD* John H. Tinker, MD* Carl V. Smith, MD[dagger] Departments of *Anesthesiology and [dagger]Obstetrics and Gynecology; University of Nebraska Medical Center; Omaha, NE 68198-4455
Parasitism of photosynthetic dinoflagellates in a shallow subestuary of Chesapeake Bay, USA (1996)

Rhode Rlver (USA) populatlons of the red-tlde d~noflagellates Gyrnnodinium sanguineum Hlrasaka, 1922, Cyi-odinium uncatenum Hulburt, 1957, and Scnppsiella trochoidea (Steln) Loeblich 111, 1976, were commonly infected by thelr parasltlc relative Amoebophrya cei-atil Cachon, 1964, d u n n g the summer of 1992. Mean ~nfection levels were relatively low, wlth data for vertically Integrated samples averaging 1.0, 1.9, and 6 5 % for G. sangujneum, G. uncatenum, and S , trocho~dea, respectively However, epldemlc outbreaks of A. ceratii (20 to 8 0 % hosts parasitized) occurred in G. uncatenum a n d S. trochoidea on several occasions, wlth peak levels of parasitism associated wlth decreases ~n host abundance. Estimates for paraslte Induced mortality indlcate that A, ceratil 1s capable of removlng a significant fraction of dinoflagellate blomass, with epldemics In the upper estuary cropplng u p to 5 4 % of the dominant bloom-forming species, G uncatenum, dally. However, epldemics were usually geographically restncted and of short duration, with dally losses for the 3 host species d u e to parasitism averaging 1 to 3 % over the summer. Thus, A ceratli appears capable of exerting a controlling Influence on bloonl-form~ng dinoflagellates of the Rhode River only when conditions a r e suitable for production of epidemlc infections. Interestingly, epidemics falled to occur in multlple d~noflagellate taxa sunultaneously, even when alternate host specles were present at hlgh densities. This observation, along with laboratory experiments demonstrating that parasites Isolated from G sanguineum wcre unable to infect G. uncatenum, S. trocholdea, and Ceratium furca, suggests that the dinoflagellate taxon A cerati] may represent a cluster of relatively host-speclfic specles.
Characterization of Novel Cationic Aminohydroxysiloxanes (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCharacterization of Novel Cationic AminohydroxysiloxanesJanis G. Matisons and Arthur ProvatasCite this: Macromolecules 1994, 27, 12, 3397–3405Publication Date (Print):June 1, 1994Publication History Published online1 May 2002Published inissue 1 June 1994https://pubs.acs.org/doi/10.1021/ma00090a039https://doi.org/10.1021/ma00090a039research-articleACS PublicationsRequest reuse permissionsArticle Views337Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
A study of active tonal noise control for a small axial flow fan (2005)

Sound radiated by a computer cooling fan consists of tones which are phase locked with the rotation, and other less deterministic tones and broadband random noise. This paper demonstrates the feasibility of globally eliminating the rotation-locked tones by applying a very simple destructive interference to a modified cooling fan with the number of struts equal to the number of rotor blades. The rig consists of a miniature electret microphone used as a rotation sensor, an ordinary loudspeaker, and a bandpass filter with adjustable amplitude and phase delay. The microphone is located at the inlet bellmouth of the fan to pick up the fluctuating aerodynamic pressure caused by the passing rotor blades. The pressure spectrum is rich in the blade passing frequency (BPF) and its low-order harmonics. It provides much better performance than a pulse-generating tachometer. Analysis of the original fan noise shows that about 90% of the radiated tonal sound is phase locked with rotation, and this portion is almost completely eliminated in all directions. The reductions of the radiated sound power in the first two BPFs are 18.5 and 13.0 dB, respectively, and the overall sound power reduction is 11.0 dB.
Dietary deprivation extends lifespan in Caenorhabditis elegans (2006)

Dietary restriction (DR) is well known as a nongenetic intervention that robustly extends lifespan in a variety of species; however, its underlying mechanisms remain unclear. We have found in Caenorhabditis elegans that dietary deprivation (DD) during adulthood, defined as removal of their food source Escherichia coli after the completion of larval development, increased lifespan and enhanced thermotolerance and resistance to oxidative stress. DD-induced longevity was independent of one C. elegans SIRTUIN, sir-2.1, which is required for the effects of DR, and was independent of the daf-2/insulin-like signaling pathway that independently regulates longevity and larval diapause in C. elegans. DD did not significantly alter lifespan of fem-1(hc17); eat-2(ad465) worms, a genetic model of DR. These findings suggest that DD and DR share some downstream effectors. In addition, DD was detrimental for longevity when imposed on reproductively active young adults, suggesting that DD may only be beneficial in the absence of competing metabolic demands, such as fertility. Adult-onset DD offers a new paradigm for investigating dietary regulation of longevity in C. elegans. This study presents the first evidence that long-term DD, instead of being detrimental, can extend lifespan of a multicellular adult organism.
Web services choreography and orchestration in Reo and constraint automata (2007)

Currently web services constitute one of the most important topics in the realm of the World Wide Web. Composition of web services lets developers create applications on top of service-oriented computing platforms. Current web services choreography and orchestration proposals, such as BPELAWS, WSCDL, and WSCI, provide notations for describing the message flows in web service interactions. However, such proposals remain at the description level, without providing any kind of formal reasoning mechanisms or tool support for checking the compatibility of web services based on the proposed notations. In this paper, we present our work on compositional construction of web services using the Reo coordination language and constraint automata. Reo is an exogenous coordinational language based on channels. We investigate the possibility of representing the behaviour of web services using constraint automata as black-box components within Reo circuits. We describe the orchestration of web services by the product of corresponding constraint automata, and use Reo circuits for choreography of web services. We investigate the issues of description, orchestration, and choreography of web services at a unifying abstract level, based on constraint automata, which have been used as the semantics of the coordination language Reo, allowing us to derive a natural correspondence relationship between orchestration and choreography.
Antigen-antibody reactions in gel single diffusion: theoretical considerations (1958)

J. A. Spiers and R. Augustin, Trans. Faraday Soc., 1958, 54, 287 DOI: 10.1039/TF9585400287
On the Coupling Boundary Integral and Finite Element Methods for the Exterior Stokes Problem in 3-D (1987)

Variational techniques coupled with nonlocal boundary conditions at some finite artificial boundary are used to establish the well-posedness of a finite problem and its equivalence to the exterior Stokes problem in three dimensions. Questions related to the existence, uniqueness, regularity and approximations of the solutions by finite elements are discussed. We obtain error estimates between the actual solution and the discretized solutions over the finite region.
Identification of Cytokeratin 18 as a Biomarker of Mouse and Human Hepatosplenic Schistosomiasis (2011)

Previously, we demonstrated unique protein expression patterns in 20-week-Schistosoma mansoni-infected CBA/J mice with moderate splenomegaly syndrome (MSS) or hypersplemomegaly syndrome (HSS). To better understand the development of severe pathology, we compared the two-dimensional differential in-gel electrophoresis (2D-DIGE) proteomic signatures of livers from uninfected mice and mice infected for 6, 8, 12, or 20 weeks and found significant changes in collagen isoforms, interleukin-2 (IL-2), cytokeratin 18, hydroxyproline, S. mansoni phosphoenolpyruvate carboxykinase, major urinary protein isoforms, and peroxiredoxin 6. Cytokeratin 18, hydroxyproline, and connective tissue growth factor (CTGF) were chosen for analysis in mouse and human sera using targeted biochemical assays. Consistent with the liver analysis, cytokeratin 18, CTGF, and hydroxyproline were significantly elevated in sera from mice with HSS compared to those from uninfected mice or mice with MSS. Moreover, cytokeratin 18 and CTGF were found to be markers for subjects with hepatosplenic and intestinal schistosomiasis, respectively, while serum hydroxyproline was a strong indicator of fibrosis for severe HS. These findings indicate that schistosome-associated changes to the liver can be detected in the serum and reveal the potential for cytokeratin 18 to be used as a diagnostic marker for early detection of hepatosplenic schistosomiasis.
Blockade of interleukin 10 potentiates antitumour immune function in human colorectal cancer liver metastases (2022)

Neutralising the effects of IL-10 in human CRLM has therapeutic potential as a stand-alone treatment and to augment the function of adoptively transferred CAR-T cells.
Hydrophobic Polydimethylsiloxane (PDMS) Coating of Mesoporous Silica and Its Use as a Preconcentrating Agent of Gas Analytes (2014)

Mesoporous silica with mean pore size of ∼14 nm was coated by polydimethylsiloxane (PDMS) using a thermal deposition method. We showed that the inner walls of pores larger than ∼8 nm can be coated by thin layers of PDMS, and the surfaces consisting of PDMS-coated silica were superhydrophobic, with water contact angles close to 170°. We used the PDMS-coated silica as adsorbents of various gas-phase chemical warfare agent (CWA) simulants. PDMS-coated silica allowed molecular desorption of various CWA simulants even after exposure under highly humid conditions and, therefore, is applicable as an agent for the preconcentration of gas-phase analytes to enhance the sensitivities of various sensors.