gebhart/patrepeval huggingface dataset:
Report of the committee on chromosome rearrangements in neoplasia and on fragile sites (1985)

Research Articles| June 15 2010 Report of the committee on chromosome rearrangements in neoplasia and on fragile sites Subject Area: Genetics R. Berger; R. Berger Search for other works by this author on: This Site PubMed Google Scholar C.D. Bloomfield; C.D. Bloomfield Search for other works by this author on: This Site PubMed Google Scholar G.R. Sutherland G.R. Sutherland Search for other works by this author on: This Site PubMed Google Scholar Cytogenetics and Cell Genetics (1985) 40 (1-4): 490–535. https://doi.org/10.1159/000132181 Article history Published Online: June 15 2010 Content Tools Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation R. Berger, C.D. Bloomfield, G.R. Sutherland; Report of the committee on chromosome rearrangements in neoplasia and on fragile sites. Cytogenetics and Cell Genetics 31 December 1985; 40 (1-4): 490–535. https://doi.org/10.1159/000132181 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsCytogenetic and Genome Research Search Advanced Search This content is only available via PDF. 1985Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Article PDF first page preview Close Modal You do not currently have access to this content.
Shape-changing polymers for biomedical applications (2018)

Smart polymers that are capable of controlled shape transformations under external stimuli have attracted significant attention in the recent years due to the resemblance of this behavior to the biological intelligence observed in nature. Moreover, shape-morphing polymer-based materials are great candidates for biomedical applications due to their adaptive properties, controlled shape transformations, and enriched functionality. In this review, we focus on the recent progress in the field of shape-memory and shape-changing polymers, highlighting their most promising applications in the biomedical field. We include a brief theoretical background on the underlying molecular mechanisms, classification of the polymer systems based on their mechanical properties, and the most promising state-of-the-art processing techniques for the fabrication of intelligent polymer-based materials. The aim of this review is to provide a link between the diverse stimuli-responsive polymer systems and their mechanical properties, and to highlight the most appealing up-to-date biomedical applications for shape-morphing systems.
BEITRAG DER MOTORENTECHNIK ZUR LOESUNG DER UMWELTPROBLEME DES KRAFTFAHRZEUGVERKEHRS (1991)

Untersucht wird der Beitrag der Motorentechnik und -entwicklung zur Loesung der Emissions- und Umweltprobleme. Dazu wird zunaechst ein knapper Ueberblick ueber die bisherige Entwicklung der Abgasreinigung gegeben. Danach wird am Beispiel der neuen SL-Baureihe von Mercedes-Benz der aktuelle Stand der Abgasreinigungstechnik behandelt. Weitere Schritte bei der Schadstoff-Reduzierung bei Otto-Motoren werden aufgezeigt. Danach befasst sich der Beitrag mit dem Diesel-Motor mit Abgasrueckfuehrung und Katalysator. Zum Abschluss untersucht der Verfasser Entwicklungstendenzen bei der Russfiltertechnik und der Regenerationsunterstuetzung durch Additive sowie kuenftige Antriebs- und Kraftstoffkonzepte. Siehe auch IDS-Nummer 327980.
Heavy Oil and Bitumen Recovery Using Radiofrequency Electromagnetic Irradiation and Electrical Heating: Theoretical Analysis and Field Scale Observations (2010)

Abstract Heavy-oil and bitumen recovery from difficult geological media such as deep, heterogeneous and high shale content sands and carbonates, and oilshale reservoirs requires techniques other than conventional thermal and miscible injection methods. Materials in oil reservoirs (formation water, crude oil, oil-water emulsions, bitumen and their components like resins, asphaltenes, and paraffin) are non-magnetic dielectric materials with low electrical conductivity. If the electromagnetic field can be created to change these properties, electro-thermo controlled hydrodynamics could improve the displacement and recovery of heavy-oil/bitumen. This paper deals with the recovery improvement of heavy-oil/bitumen by Radio-Frequency (RF) Electromagnetic (EM) radiation. The RF-EM fields in the form of waves can penetrate deeply enough - from fractions of a meter to several hundred meters - into oil and gas containing reservoirs to generate heat and eventually improve recovery mainly due to the reduction of oil viscosity. The recovery mechanisms and the dynamics of the RF-EM heating process were analyzed for several field scale applications in Russia. In the Yultimirovskaya tar sand deposits, RF-EM energy was transmitted from the RF-EM generator, located at the surface, into the formation by a coaxial system of the well pipes. Another field example analyzed was the RF-EM stimulation process in several wells of the Mordovo-Karmalskaya tar sands performed in the 1980s. It was observed that the formation was heated to the temperature which was sufficient for injection of oxidant (air) to initiate fire flooding. Then, a mathematical model of this process was presented with a sample exercise. Some data needed for this exercise were obtained from the field tests evaluated. Field tests proved the efficiency of the RF-EM stimulation of heavy oil / bitumen deposits with low water cut values (in operating production wells with water cut &amp;lt;30% on early field development stages). Numerical simulations suggest that bottomhole temperature and heat/mass transfer effects in the reservoir can be controlled by setting the output performance of the RF generator and by the difference between the reservoir and bottom-hole pressure.
An Improved Joint Timing and Frequency Synchronization Algorithm for OFDM (2010)

An improved OFDM joint timing and frequency synchronization algorithm is proposed based on Schmidl algorithm aimed at the synchronization problem of orthogonal frequency division multiplexing (OFDM). It only requires one training symbol, and it makes an improvement to the method of symbol timing and integer frequency offset estimation in Schmidl algorithm. The estimation range of the proposed method is as large as the bandwidth of the OFDM signal, and the plateau in Schmidl algorithm is eliminated. The simulation results show that the improved algorithm has robust performance.
Beyond physical bar charts (2014)

Physical visualizations only recently started to attract attention from the InfoVis and HCI communities. They are well known to encourage playful exploration and to stimulate curiosity, but are also considered to support analytical information visualization tasks. However, creating effective and usable physical visualizations has not been explored in much detail. In this work, we present our early approaches and experiences in designing and building novel physical visualizations. We started with sketches on paper, created first low fidelity prototypes out of cardboard and built the final visualizations with thread, acrylic glass and a laser cutter. An initial user study was conducted to investigate if basic information retrieval tasks can be accomplished with our physical visualizations and how users interact with them.
Beyond RCS: Capitalizing on address book to embrace multimedia services (2009)

This document introduces PRISM, an application of multi-domain address book which provides a global and simple access point to communication and multimedia services independently of existing application silos. PRISM also enriches the address book with IMS based network services such as Extended Presence and Personal Data Synchronization which free the end users from devices constraints. As PRISM is a client-server solution which is by design extensible to any domain of use, it defines an enabling platform for the introduction and the management of end users services on both fixed and mobile devices.
Accuracy-Guaranteed Bit-Width Optimization (2006)

An automated static approach for optimizing bit widths of fixed-point feedforward designs with guaranteed accuracy, called MiniBit, is presented. Methods to minimize both the integer and fraction parts of fixed-point signals with the aim of minimizing the circuit area are described. For range analysis, the technique in this paper identifies the number of integer bits necessary to meet range requirements. For precision analysis, a semianalytical approach with analytical error models in conjunction with adaptive simulated annealing is employed to optimize the number of fraction bits. The analytical models make it possible to guarantee overflow/underflow protection and numerical accuracy for all inputs over the user-specified input intervals. Using a stream compiler for field-programmable gate arrays (FPGAs), the approach in this paper is demonstrated with polynomial approximation, RGB-to-YCbCr conversion, matrix multiplication, B-splines, and discrete cosine transform placed and routed on a Xilinx Virtex-4 FPGA. Improvements for a given design reduce the area and the latency by up to 26% and 12%, respectively, over a design using optimum uniform fraction bit widths. Studies show that MiniBit-optimized designs are within 1% of the area produced from the integer linear programming approach
Models for Numerical Evaluation of Variable Speed Different Wind Generator Systems (2007)

Wind energy is currently one of the most cost-effective energy sources to produce electricity among various renewable energy sources. During last two decades, various wind turbine concepts with different generator systems have been developed and built. It is necessary to identify the most cost-effective wind conversion system among the various possible configurations. The aim of this project is to evaluate the suitable cost- effective wind generator systems by using the optimization designs and the numerical comparison. The research report is made of two parts, one focus on the design models of different wind generator systems, the other presents the optimization results and evaluation of variable speed wind generator systems. In this report, firstly, it gives an overview of various wind generator topologies, including their advantages and disadvantages, market status and developing trends. Next, the analytical models include the wind turbine power characteristics; the single/threestage gearbox and the power electronic converter for possible wind turbine concepts are described. Finally, the electromagnetic design models of the investigated generator topologies are presented, including the squirrel cage induction generator (SCIG), the doubly-fed induction generator (DFIG), the electrically excited synchronous generator (EESG) and permanent magnet synchronous generator (PMSG). Numerical evaluation with optimized design and comparison of variable speed wind generator systems by using the presented models will be introduced in report 2.
Faculty of Chemical Engineering and Technology, Self-evaluation Report 2014./2015. (2015)

Radi se o samoanalizi Fakulteta kemijskog inženjerstva i tehnologije Sveucilista u Zagrebu u skolskoj godini 2014./2015.
Fluorescence polarization of six membrane probes in embryonal carcinoma cells after differentiation as measured on a FACS II cell sorter (1984)

Fluorescence polarization measurements on a FACS II cell sorter were compared with static measurements on a spectrofluorimeter using calibration solutions and Hoechst 33258-labeled cells. For the flow cytometric measurements on the FACS we used a pseudodepolarizer for normalization of the output of the two photomultipliers. The results showed that fluorescein and fluoresceinated bovine serum albumin (BSA) solutions gave identical values on both instruments. The mean value for fluorescence polarization of Hoechst 33258-labeled cells as measured on the FACS was the same as the value obtained with the spectrofluorimeter. Subsequently the fluorescence polarization of six different membrane probes was determined using differentiating embryonal carcinoma cells as a model system. Differentiation was induced by treatment of the cells with retinoic acid together with cyclic AMP. With diphenylhexatriene (DPH) the fluorescence polarization increased from I/I = 1.55 to 1.74 upon differentiation. With a charged analog of DPH (TMA-DPH) fluorescence polarization increased from I/I = 1.87 to 2.02. No appreciable changes in fluorescence polarization were observed in this cell system when anthroyloxysterate probes (12-AS, 9-AS, 6-AS, 2-AS) were used.
The Relationship Between Signs of Cardiovascular Deficiency and Cognitive Performance in Old Age: A Population-Based Study (2000)

The influence of cardiovascular signs (CVS) on cognitive performance was examined in 227 older adults not suffering from dementia between 75 and 96 years of age who were sampled from the community. Participants received a comprehensive physical examination that included specific evaluation of current CVS, including dyspnea, cardiac murmur, and edema in lower limbs. They were administered tests of digit span, episodic recall and recognition, verbal fluency, and visuospatial skill. CVS were found to predict performance on tests of episodic memory and visuospatial skill, after the effects of age, education, gender, relevant drug use, and mood symptoms were controlled for. Although CVS accounted for relatively little general performance variation, the findings are relevant to the understanding of normal variation in late-life cognitive performance. Finally, CVS increased with age and accounted for a sizable proportion of the age-related cognitive variation.
Synergistic Neurotoxic Effects of Arsenic and Dopamine in Human Dopaminergic Neuroblastoma SH-SY5Y Cells (2007)

Parkinson's disease is an environmentally influenced, neurodegenerative disease of unknown origin that is characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta of the brain. Arsenic is an environmental contaminant found naturally in ground water, industrial waste, and fertilizers. The initial goal of the present study was to determine if a mixture of arsenite (As+3) and dopamine (DA) could cause enhanced degeneration of dopaminergic neuronal cells. Additional goals were to determine the mechanism (apoptosis or necrosis) of As- and DA-induced cell death and if death could be attenuated by antioxidants. The cell culture model employed was the SH-SY5Y neuroblastoma cell line that has been shown to possess differentiated characteristics of dopaminergic neurons. The results demonstrated that a mixture of As+3 and DA was synergistic in producing the death of the SH-SY5Y cells when compared with exposure to either agent alone. A mixture of 10μM As+3 and 100μM DA produced almost a complete loss of cell viability over a 24-h period of exposure, whereas, each agent alone had minimal toxicity. It was shown that necrosis, and not apoptosis, was the mechanism of cell death produced by exposure of the SH-SY5Y cells to the mixture of As+3 and DA. It was also demonstrated that the antioxidants, N-acetylcysteine, and Sulforaphane, attenuated the toxicity of the mixture of As+3 and DA to the SH-SY5Y cells. This study provides initial evidence that As+3 and DA synergistically can cause enhanced toxicity in cultured neuronal cells possessing dopaminergic differentiation.
Tanshinone I attenuates proliferation and chemoresistance of cervical cancer in a KRAS‐dependent manner (2018)

Chemoresistance is a common occurrence during advanced or recurrent cervical cancer therapy when treated by conventional treatment, platinum-based chemotherapy. This study aimed to investigate the effect and underlying mechanism of tanshinone I on attenuating proliferation and chemoresistance of cervical cancer cells. In cervical cancer cells, cell proliferation was examined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), cell count, and soft-agar colony-formation assay. rVista analysis and luciferase reporter assay were used to explore the upstream regulator of KRAS, and the expression levels of key genes were also detected. Western blot analysis showed that tanshinone I significantly suppressed KRAS expression and inhibited AKT phosphorylation. rVista analysis and luciferase reporter assay demonstrated that ELK1 can binds directly to KRAS promoter and positively regulates KRAS expression. MTT assay showed that KRAS or ELK1 overexpression significantly attenuated the suppressive effects of tanshinone I on HeLa cells proliferation. In addition, tanshinone I recovered the cisplatin sensitivity of HeLa CR cells, whereas KRAS or ELK1 overexpression significantly inhibited this phenomenon. Our results suggested that tanshinone I had anticancer effects on cervical cancer cells via inhibiting ELK1 and downregulating KRAS-AKT axis, which subsequently suppressed the proliferation and cisplatin resistance of cervical cancer cells.
Intercalibration of medium-resolution grating spectrometers for MOPITT validation (1999)

The validation of MOPITT measurements of atmospheric carbon monoxide (CO) and methane (CH<SUB>4</SUB>) will require independent, simultaneous, co-located measurements from ground- and aeroplane-based instruments. Recently, a program of MOPITT validation measurements in Russia and Canada has been proposed. This program will use three (nearly) identical Russian-made medium-resolution grating spectrometers (known as Sarcophagus) capable of measuring the atmospheric column concentration of CO and CH<SUB>4</SUB>. Two of these instruments are located in Russia, and one in Canada. The similarity of these instruments provides the opportunity of acquiring a highly correlated validation dataset from diverse locations around the globe. As part of this program, we are proposing to inter- calibrate these instruments using a set of standard gas cells. These cells will be regularly shipped between the instruments for calibration and inter-comparison purposes. These measurements will be made relative to measurements from a very high-resolution Difference Frequency Laser Spectrometer (DFLS) located at the University of Toronto. In this paper we present the results of a test of this inter-calibration experiment using a single CO gas cell and involving Sarcophagus, a high resolution Fourier Transform Spectrometer (FTS) and the University of Toronto DFLS.
Location of the 18/28S ribosomal RNA genes in two Hawaiian Drosophila species by monoclonal immunological identification of RNA.DNA hybrids in situ. (1981)

Using both heterologous rabbit antisera and mouse monoclonal antibody to RNA.DNA hybrids, we have mapped the in situ hybridization locus of the 18/28S ribosomal RNA fraction to a single large band on polytene autosome 3 in Drosophila heteroneura and Drosophila silvestris. This portion of the chromosome is not physically connected with the nucleolus at the end of larval salivary gland development. In mature larvae, little or no hybridization with the material in the nucleolus can be detected. In younger larvae, hybridization of the ribosomal RNA probe to the nucleolus itself can be observed. The chromosome 3 locus is the only band in the polytene genome that shows variation in size and intensity of staining between populations and species. The interband chromosome regions that are immediately distal or proximal to the 18/28S rRNA locus have been involved in a disproportionately large number of natural inversion breaks observed in the euchromatic portion of the polytene chromosome. In 104 species of Hawaiian Drosophila in which chromosome 3 polytene sequences have been determined, 15 breaks occur in these two regions. On a random basis, only one such break is expected. We propose that this locus may be flanked by substantial heterochromatic blocks which are not represented in the salivary gland chromosome.
Reaction of N-substituted thioamides with gem-dicyano epoxides: a new synthetic route to anhydro-4-hydroxythiazolium hydroxides (1978)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReaction of N-substituted thioamides with gem-dicyano epoxides: a new synthetic route to anhydro-4-hydroxythiazolium hydroxidesMichele Baudy, Albert Robert, and Andre FoucaudCite this: J. Org. Chem. 1978, 43, 19, 3732–3736Publication Date (Print):September 1, 1978Publication History Published online1 May 2002Published inissue 1 September 1978https://pubs.acs.org/doi/10.1021/jo00413a023https://doi.org/10.1021/jo00413a023research-articleACS PublicationsRequest reuse permissionsArticle Views230Altmetric-Citations44LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts