gebhart/patrepeval huggingface dataset:
Ion Sources for Ion Machining Applications (1977)

Ion sources with beam diameters of 2.5, 10, and 20 cm have been developed for ion machining applications. All three of these sources use carbon grids to minimize accelerator grid sputtering. A new starting circuit Is also employed that uses only passive components for initiation of the discharge. The two larger sources use a flat multipole chamber with multiple cathodes to generate a very uniform beam. The multipole magnetic field is integrated into the anode, which greatly reduces the required number of insulating supports.
The artificial endocrine pancreas in clinical practice and research. The present position and future perspectives. (1993)

The artificial endocrine pancreas (AEP) is a controlled glucose and/or insulin infusion system in which continuously monitored blood sugar values are fed to a computerised analyser that uses predetermined algorithms to establish the doses to be administered. Since its first appearance in clinical practice and diabetological research during the Sixties, the AEP has been modified in various ways to overcome technical problems associated with the gluco-sensor and algorithms so as to make better use of the glucose-insulin feedback mechanism, and hence obtain a closer correspondence to physiological islet cell activity. As a result of these changes, the AEP can be employed in accordance with the physiopathological principles of insulin secretion in a variety of clinical conditions to secure the short-term control of metabolic alterations in the diabetic. Surgery is one field in which the AEP is used to great advantage, since this and its accompanying anaesthetics are the source of stress, which in turn may result in a rapid and sometimes serious postoperative metabolic derangement, including an increased secretion of anti-insulin hormones. The AEP has also been proposed for diabetic pregnancy and for the treatment of subjects in diabetic coma. It has proved useful in the diagnosis and management of hypoglycaemia due to organic hyperinsulinism, in diabetics with renal failure, in the honeymoon period, and in cases of unstable diabetes. The versatility of its application and its underlying physiopathological principles have enabled the AEP to be predominantly employed in research.(ABSTRACT TRUNCATED AT 250 WORDS)
Practical optimal state feedback control law for continuous-time switched affine systems with cyclic steady state (2009)

In this article, a method for computing an optimal state feedback control law for continuous-time switched affine systems exhibiting cyclic behaviour in steady state is presented. The hybrid solutions are deduced from the Fillipov solutions. It is shown that the optimal trajectory synthesis implies to determine singular arcs. Algebraic conditions are given to obtain these particular arcs of the trajectory. A numerical procedure is then proposed to generate optimal trajectories on a given state space area avoiding the classical two-point boundary value problem occurring in optimal control synthesis. The interpolation of the solutions set, through a neural network, yields a state feedback control law. Several examples in the power converters field show the feasibility and the efficiency of the method.
Liver stiffness reduction correlates with histological characteristics of hepatitis C patients with sustained virological response (2017)

Pre-treatment histological characteristics influence LS reduction after SVR is achieved.
Execution Patterns (2014)

To fully understand SQL Server 2014 Integration Services execution, you must first understand the different deployment models. There are two: the package deployment model and the project deployment model. Each exposes and supports a different functionality. The package deployment model primarily supports legacy functionality. It is the model used in SSIS 2005 through SSIS 2008 R2. The new way of doing things involves the project deployment model. Certain execution methods, but not all, are available to both deployment models.
Investigation of Surface Modification of Polystyrene by a Direct and Remote Atmospheric-Pressure Plasma Jet Treatment (2020)

Localized functionalization of polymer surface with an atmospheric-pressure plasma jet was investigated at various treatment conditions. Polystyrene samples were treated with the plasma jet sustained in argon under direct or remote conditions. The two-dimensional evolution of surface wettability and the spot size of the treated area was determined systematically by measuring apparent water contact angles. Modification of surface chemistry and the formation of functional groups were investigated by X-ray photoelectron spectroscopy (XPS). The saturation of surface wettability and functional groups was observed even after a second of treatment providing the sample was placed close to the exhaust of the discharge tube. The spot diameter of the modified area increased logarithmically with increasing treatment time. However, it decreased linearly when increasing the distance. At the edge of the glowing plasma, however, the modification of surface properties was more gradual, so even 30 s of treatment caused marginal effects. With a further increase in the distance from the edge of the glowing plasma, however, there were no further treatment effects. The results are explained by significant axial as well as radial gradients of reactive species, in particular hydroxyl radicals.
Measurements of total ionizing dose effects in TPSCo 65 nm and influence of NMOS bulk bias (2023)

Abstract The CERN EP R&amp;D WP 1.2 aims to develop state-of-art monolithic pixel detectors using modern CMOS processes. The TPSCo 65 nm process is a suitable candidate and its radiation tolerance and sensor performance are therefore being studied. The impact of the back bias on the transistor behavior has also been measured to provide the designers with accurate models. This process shows sensitivity to radiation and degradation mechanisms similar to previously studied 65 nm CMOS technologies, strongly dependent on the geometry of the transistors. This paper presents preliminary characterization results of this technology that can serve as a guideline for designers.
Extensive Metabolizers of Debrisoquine Become Poor Metabolizers during Quinidine Treatment (1987)

Seven male patients (age 55-75 years) were debrisoquine-tested immediately before and after one week of treatment with quinidine sulphate (200 mg X 3-4 day-1). Before quinidine all patients were classified as extensive metabolizers (metabolic ratio 0.1-3.6). During quinidine the formation of 4-OH-debrisoquine was practically abolished and the phenotype of the patients was altered to PM (metabolic ratio 15-51). This is probably due to an inhibition of debrisoquine hydroxylation by quinidine. Inhibition of 4-OH-debrisoquine formation was associated with a disproportionate increase in debrisoquine excretion.
Compound image compression by multi-stage prediction (2012)

Computer generated compound images contain not only photographic images but also text and graphics images, which makes it difficult to be efficiently compressed using exiting image and video coding standards. This paper presents a new compound image coding scheme based on the intra coding framework of the upcoming high efficiency video coding (HEVC) standard. The proposed scheme first decomposes the compound image into color components and structure components. Then two-stage prediction scheme is employed to exploit the correlation among structure components, where the first prediction is generated by directional prediction and second prediction is generated by template matching. Experimental results show that the proposed scheme achieves up to 10.2 dB coding gain on compound images compared with HEVC. And on average it achieves 42.2 percent bitrate saving compared with HEVC.
AUTOBEST: a united AUTOSAR-OS and ARINC 653 kernel (2015)

This paper presents AUTOBEST, a united AUTOSAR-OS and ARINC 653 RTOS kernel that addresses the requirements of both automotive and avionics domains. We show that their domain-specific requirements have a common basis and can be implemented with a small partitioning microkernel-based design on embedded microcontrollers with memory protection (MPU) support. While both, AUTOSAR and ARINC 653, use a unified task model in the kernel, we address their differences in dedicated user space libraries. Based on the kernel abstractions of futexes and lazy priority switching, these libraries provide domain specific synchronization mechanisms. Our results show that thereby it is possible to get the best of both worlds: AUTOBEST combines avionics safety with the resource-efficiency known from automotive systems.
Room temperature laser emission of (Ga,In)(N,As)/Ga(As,Sb)/(Ga,In)(N,As) type‐II ‘W’ quantum well heterostructures (2022)

Abstract For the first time, room temperature laser emission of an electrically pumped edge emitting laser device based on (Ga,In)(N,As)/Ga(As,Sb)/(Ga,In)(N,As) type‐II W’ quantum well heterostructures is shown. The device was grown using metal organic vapour phase epitaxy utilising the alternative nitrogen precursor di‐ tert ‐butyl‐amino‐arsane and characterised with electroluminescence spectroscopy. At low current densities, the emission wavelength was 1339 nm. It shifted blue with 4.26 meV/(kA/cm 2 ) until the threshold current density was reached. At that point, the peak emission wavelength reached 1270 nm. With a cavity length of 2012 μm, the investigated device reached lasing threshold at 9.5 kA/cm 2 .
Evaluation of ro for Propagation Down Through the Atmosphere (1974)

The concept of the quantity r(o) as a length that measures the effect of atmospheric turbulence on optical systems that are wavefront distortion sensitive is briefly reviewed. It is pointed out that no precise set of data on r(o) for propagation down through the atmosphere has been published. Using astronomical seeing data obtained by Hoag and by Meinel it is shown how statistics for r(o) can be derived, at least for observatory quality sites. We find that the two sets of data are in very good agreement and conclude that r(o) is variable from night to night and distributed according to a log-normal distribution. For 0.55-microm light and zenith propagation, the median value of r(o), is 0.114 m and changes by a factor of 1.36 for occurrences one standard deviation from the median.
[Systemic lupus erythematosus manifested by thrombophlebitis of the lower limbs]. (1980)

The diagnosis of systemic lupus erythematosus was made in a 9 year old boy who had presented two months earlier with an extensive thrombosis of the inferior vena cava and femoral veins. Haemostatic abnormalities were detected as follows: a moderate thrombocytopenia, increased platelet aggregation and stickiness, and a circulating anticoagulant (antithromboplastin).
A GNSS/IMU/WSS/VSLAM Hybridization Using an Extended Kalman Filter (2015)

International audience
Roman perceptions of blacks (1993)

Certain preconceptions about 'blacks' in predominantly 'white' societies have distorted modern visions of the ways in which Aethiopes were perceived in Roman society, resulting in much misinterpretation of the relevant texts. In Roman perceptions categories like black African, white, 'paleface' and swarthy were neither communities nor socially defined 'races' with ascribed group-statuses. Categorisation was determined by the physical appearance of the individual person, not by parentage or 'blood'.
A population‐based comparison of treatment patterns, resource utilization, and costs by cancer stage for Ontario patients with triple‐negative breast cancer (2020)

Per-patient costs were higher in metastatic TNBC, despite a less frequent use of all treatment modalities compared to early TNBC. Treatment patterns were aligned with the options available at the time; however, neoadjuvant treatment rates were low.
Micro-structured fiber interferometer as sensitive temperature sensor (2013)

We report on a fast and sensitive temperature sensor using a micro-structured or photonic crystal fiber interferometer with a high germanium doped fiber core. The wavelength sensitivity for temperature variation was as high as Δλ/ΔT= 78 pm/°C up to 500 °C, which was 6 times more sensitive than the fiber Bragg grating temperature sensitivity of Δλ/ΔT= 13 pm/°C at 1550 nm. The sensor device was investigated concerning the sensitivity characteristics and response time.
Simple path selection for optimal routing on processor arrays (1992)

Article Free Access Share on Simple path selection for optimal routing on processor arrays Authors: Christos Kaklamanis View Profile , Danny Krizanc View Profile , Satish Rao View Profile Authors Info & Claims SPAA '92: Proceedings of the fourth annual ACM symposium on Parallel algorithms and architecturesJune 1992 Pages 23–30https://doi.org/10.1145/140901.140904Published:01 June 1992Publication History 13citation290DownloadsMetricsTotal Citations13Total Downloads290Last 12 Months12Last 6 weeks7 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
UVG dataset (2020)

This paper provides an overview of our open Ultra Video Group (UVG) dataset that is composed of 16 versatile 4K (3840×2160) test video sequences. These natural sequences were captured either at 50 or 120 frames per second (fps) and stored online in raw 8-bit and 10-bit 4:2:0 YUV formats. The dataset is published on our website (ultravideo.cs.tut.fi) under a non-commercial Creative Commons BY-NC license. In this paper, all UVG sequences are described in detail and characterized by their spatial and temporal perceptual information, rate-distortion behavior, and coding complexity with the latest HEVC/H.265 and VVC/H.266 reference video codecs. The proposed dataset is the first to provide complementary 4K sequences up to 120 fps and is therefore particularly valuable for cutting-edge multimedia applications. Our evaluations also show that it comprehensively complements the existing 4K test set in VVC standardization, so we recommend including it in subjective and objective quality assessments of next-generation VVC codecs.
Selection of a Water-Soluble Salt Form of a Preclinical Candidate, IIIM-290: Multiwell-Plate Salt Screening and Characterization (2018)

IIIM-290, a semisynthetic derivative of natural product rohitukine, is an orally bioavailable Cdk inhibitor, efficacious in the xenograft models of colon, pancreatic, and leukemia cancer. Its low aqueous solubility (∼8.6 μg/mL) could be one of the reasons for achieving optimal in vivo efficacy relatively at a higher dose. Being a nitrogenous compound, salt formation was envisaged as one of the ideal approaches to enhance its solubility and dissolution profile. Thus, herein, a solubility-guided miniaturized 96-well plate salt screening protocol was devised for identification of the suitable salt form of this preclinical candidate. The solubility-guided strategy has resulted in the identification of hydrochloride as the most favorable counterion, resulting in 45-fold improvement in aqueous solubility. The HCl salt was then scaled up at a gram size and characterized using <sup>1</sup>H and <sup>13</sup>C NMR, scanning electron microscopy, powder X-ray diffraction, Fourier-transform infrared, and differential scanning calorimetry studies. The HCl salt displayed enhancement in the in vitro dissolution profile as well as improved plasma exposure in the pharmacokinetic study. The oral administration of the IIIM-290·HCl salt in BALB/c mice resulted in >1.5-fold improvement in areas under the curve, <i>C</i><sub>max</sub>, and half-life. The prepared salt also did not alter its cyclin-dependent kinase (Cdk)-2 and Cdk-9 inhibition activity. This biopharmaceutically improved lead has a potential to investigate further in preclinical studies. The solubility-guided salt screening strategy implemented herein could be utilized for other preclinical leads.
ChemInform Abstract: Poly(hydroxyalkanoates): Biorefinery Polymers with a Whole Range of Applications. The Work of Robert H. Marchessault (2008)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Towards Enhancing the Security of OAuth Implementations in Smart Phones (2014)

With the roaring growth and wide adoption of smart mobile devices, users are continuously integrating with culture of the mobile applications (apps). These apps are not only gaining access to information on the smartphone but they are also able gain users' authorization to access remote servers on their behalf. The Open standard for Authorization (OAuth) is widely used in mobile apps for gaining access to user's resources on remote service providers. In this paper, we analyze the different OAuth implementations adopted by the SDKs of the popular resource providers on smartphones and demonstrate possible attacks on most OAuth implementations. By analyzing source code of more than 430 popular Android apps we summarized the trends followed by the service providers and by the OAuth development choices made by application developers. In addition, we propose an application-based OAuth Manager framework, that provides a secure OAuth flow in smartphones that is based on the concept of privilege separation and does not require high overhead.
Morphological and Cytochemical Studies on Lymphocytic Choriomeningitis Virus (1968)

Lymphocytic choriomeningitis (LCM) virus was observed by electron microscopy in thin sections of infected tissue cultures. The particles were pleomorphic and varied greatly in size. The smaller particles (50 to 200 nm) appeared to be spherical, whereas the largest (over 200 nm) were often cup-shaped. All particles contained one to eight or more electron-dense granules which were removed by ribonuclease. The particles were formed by budding from the plasma membrane and appeared to have spikes. The morphological evidence suggests that LCM should be considered as belonging to the presently unclassified group of lipoprotein-enveloped ribonucleic acid viruses.
Quality Control Methods for Several Related Variables (1959)

The methods described in an earlier article devoted to control methods for two related variables are extended to the case of more than two related variables. The concept of matrix notation is introduced because of the resultant simplification in multivariate analysis and the original two-variable problem is restated in matrix form. The method of principal components is introduced both as a method of charscterizing a multivariate process and as a control tool associated with control procedures. These methods are illustrated with a numerical example from the field of ballistic missiles. Approximate multivariate techniques, designed to simplify the administration of these control programs, are also discussed.
One-Pot Synthesis of Hierarchically Macro- and Mesoporous Carbon Materials with Graded Porosity (2015)

Hierarchically porous materials are becoming increasingly important in catalysis, separation, and energy applications due to their advantageous diffusion and flux properties. Here we present the synthesis of hierarchically macro- and mesoporous carbon materials with graded porosity from a one-pot fabrication route. Organic–polymeric hybrids of a carbon precursor and poly(isoprene)-block-poly(styrene)-block-poly(4-vinylpyridine) with graded porosity are obtained via coassembly and nonsolvent-induced phase separation. The membranes were carbonized at temperatures as high as 1100 °C with simultaneous decomposition of the block copolymer. The carbon materials show an open nanoporous top surface with narrow pore-size distribution that opens up into a graded macroporous support with increasing macropore size along the film normal and mesoporous walls, providing for highly accessible porosity with a large surface area of over 500 m2 g–1. Further, we expand the direct synthesis process to form well-dispersed metal nanoparticles (such as nickel and platinum) on the graded, hierarchically porous carbon materials. Our one-pot synthesis offers a facile approach to graded macro- and mesoporous carbons.
Suitability of oligonucleotide‐mediated cystic fibrosis gene repair in airway epithelial cells (2003)

Oligonucleotide-mediated CFTR gene repair is an inefficient process in CF airway epithelial cells. Further improvements in oligonucleotide structure, nuclear delivery and/or the capability for mismatch repair stimulation will be necessary to achieve therapeutic levels of mutation correction in these cells.
Dyadic Green's function formalism for photoinduced forces in tip-sample nanojunctions (2017)

A comprehensive theoretical analysis of photoinduced forces in an illuminated nanojunction, formed between an atomic force microscopy tip and a sample, is presented. The formalism is valid within the dipolar approximation and includes multiple scattering effects between the tip, sample, and a planar substrate through a dyadic Green's function approach. This physically intuitive description allows a detailed look at the quantitative contribution of multiple scattering effects to the measured photoinduced force, effects that are typically unaccounted for in simpler analytical models. Our findings show that the presence of the planar substrate and anisotropy of the tip have a substantial effect on the magnitude and the spectral response of the photoinduced force exerted on the tip. Unlike previous models, our calculations predict photoinduced forces that are within range of experimentally measured values in photoinduced force microscopy (PiFM) experiments.
Expanding Insight into Asymmetric Palladium‐Catalyzed Allylic Alkylation of N‐Heterocyclic Molecules and Cyclic Ketones (2013)

Eeny, meeny, miny ... enaminones! Lactams and imides have been shown to consistently provide enantioselectivities substantially higher than other substrate classes previously investigated in the palladium-catalyzed asymmetric decarboxylative allylic alkylation. Several new substrates have been designed to probe the contributions of electronic, steric, and stereoelectronic factors that distinguish the lactam/imide series as superior alkylation substrates (see scheme). These studies culminated in marked improvements on carbocyclic allylic alkylation substrates.
Effects of head-down positioning on regional central nervous system perfusion in isoflurane-anesthetized horses (2008)

Head-down positioning increased heart-brain hydrostatic gradients in isoflurane-anesthetized horses, thereby decreasing cerebral blood flow and, to a greater extent, increasing ICP. During anesthesia, CNS regions with low blood flows in horses may be predisposed to ischemic injury induced by high ICP.