gebhart/patrepeval huggingface dataset:
Prenatal testing in ICSI pregnancies: incidence of chromosomal anomalies in 1586 karyotypes and relation to sperm parameters (2002)

A significantly higher rate of de-novo chromosomal anomalies (1.6 versus 0.5% in amniocentesis for a mean maternal age of 33.5 years; P < 0.007) was observed in ICSI offspring, relating mainly to a higher number of sex chromosomal anomalies and partly to a higher number of autosomal structural anomalies. This finding was related to sperm concentration and motility. The significantly higher rate of observed inherited anomalies (1.4 versus 0.3-0.4% in prenatal tests in the general population; P < 0.001) was related to a higher rate of constitutional chromosomal anomalies, mainly in the fathers. The hypothesis of a higher risk of post-zygotic events as a consequence of the ICSI procedure leading to a higher proportion of chromosomal mosaicism was not confirmed in this study. Couples should be informed of the risks of an abnormal result related to sperm quality, and of the risk linked to a prenatal procedure as well as about the relatively benign character of some chromosomal anomalies such as de-novo structural anomalies or sex chromosomal anomalies in order to be able to make a choice for prenatal testing, or not.
A Novel Inter-Country Integrated Power Generation-Transmission Expansion Planning Model: Case Study on North-East Asia (2018)

The unbalanced distribution of energy resources and power demand in Northeast Asia determines that the optimal resources utilization needs to break national boundaries and realize transnational power transmission. In this paper, a novel inter-country integrated power generation-transmission expansion planning model is proposed to solve the issue of source-grid coordination planning in different countries in the interconnection area. Taking Northeast Asia as an example, the optimal planning results of transnational transmission capacity and installed power generation capacity in various countries are obtained under different development scenarios. The results show that the power source structure of exporting countries will impact the economic competitiveness and potential scale of interconnection.
<p>Biomedical Applications of Zeolitic Nanoparticles, with an Emphasis on Medical Interventions</p> (2020)

The advent of porous materials, in particular zeolitic nanoparticles, has opened up unprecedented putative research avenues in nanomedicine. Zeolites with intracrystal mesopores are low framework density aluminosilicates possessing a regular porous structure along with intricate channels. Their unique physiochemical as well as physiological parameters necessitate a comprehensive overview on their classifications, fabrication platforms, cellular/macromolecular interactions, and eventually their prospective biomedical applications through illustrating the challenges and opportunities in different integrative medical and pharmaceutical fields. More particularly, an update on recent advances in zeolite-accommodated drug delivery and the prevalent challenges regarding these molecular sieves is to be presented. In conclusion, strategies to accelerate the translation of these porous materials from bench to bedside along with common overlooked physiological and pharmacological factors of zeolite nanoparticles are discussed and debated. Furthermore, for zeolite nanoparticles, it is a matter of crucial importance, in terms of biosafety and nanotoxicology, to appreciate the zeolite-bio interface once the zeolite nanoparticles are exposed to the bio-macromolecules in biological media. We specifically shed light on interactions of zeolite nanoparticles with fibrinogen and amyloid beta which had been comprehensively investigated in our recent reports. Given the significance of zeolite nanoparticles' interactions with serum or interstitial proteins conferring them new biological identity, the preliminary approaches for deeper understanding of administration, distribution, metabolism and excretion of zeolite nanoparticles are elucidated.
CT-guided transsternal core biopsy of anterior mediastinal masses. (1996)

Computed tomography-guided transsternal biopsy was successful in 10 anterior mediastinal masses in 10 patients, with use of a coaxial length-matched bone biopsy system comprising an outer cannula and an inner eccentric drill bit. No complications occurred in nine of 10 biopsies (eight performed with an automatic cutting needle, two with a fine needle), with less discomfort than was caused by injection of anesthetic.
A suboptimal LMI formulation for the $H_2$ static output feedback control of hidden Markov jump linear systems (2018)

International audience
Polymorphic Forms of Organic Crystals at Room Conditions: Thermodynamic and Structural Implications (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPolymorphic Forms of Organic Crystals at Room Conditions: Thermodynamic and Structural ImplicationsA. Gavezzotti and G. FilippiniCite this: J. Am. Chem. Soc. 1995, 117, 49, 12299–12305Publication Date (Print):December 1, 1995Publication History Published online1 May 2002Published inissue 1 December 1995https://pubs.acs.org/doi/10.1021/ja00154a032https://doi.org/10.1021/ja00154a032research-articleACS PublicationsRequest reuse permissionsArticle Views1623Altmetric-Citations263LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information Get e-Alerts
Vestibular dose correlates with dizziness after radiosurgery for the treatment of vestibular schwannoma (2021)

Our results reveal that 5 Gy and above minimum vestibular doses significantly worsened dizziness. Additionally, mean and maximum doses received by the vestibule were significantly lower in patients who had improved caloric function. Further investigations are needed to determine dose-volume parameters and their effects on vestibular toxicity.
허구의 감정, 내러티브의 통속성 (2010)

본 연구는 켄달 월튼의 ``가장 상상 이론``을 통해 감상의 본질과 감정의 관계를 제시하고자 했다. 이러한 점은 예술이 초래하는 표현이 존재적으로 허 구적 일지라도 그것을 수용하는 우리 역시 상상에 의존해 보고 허구의 감정을 만든다는 의의가 있다. 중요한 것은 허구의 감정이 우리 실제 생활에 투영 되어 실제의 감정으로 이행될 수 있다는 점이다. 이런 면에서 허구적인 감정은 없다. 오늘날의 미디어 예술은 무엇보다 감상자의 능 동적인 의식 개입과 행위를 통해 적극적인 감상 행 위를 이끌어 낸다. 이때 우리가 처한 상황은 인식 작용과 인식된 대상에 따른 표현적 의미가 불리 되지 않으며, 또한 인식의 문제를 넘어선 감정이입이 내화되어있다. 허구는 우리가 알고 있는 것, 우리가 경험한 것 너머의 욕구의 문제를 담고 있다. 그래서 허구의 문제는 재현된 대상과 현상의 문제뿐 아니 라, 감상의 주체인 인간의 의식과도 깊게 관련되어 있다. 이것 때문에 허구에 대한 우리의 반응도 중요 하다. 허구와 관련해서 인지과학, 감성공학, 심리학 적 논의들은 이러한 견지에서 필요 할뿐더러, 추체험의 근본인 의식과 결부되어 있다. 위와 같은 점에 서 통속화되고 획일적인 감정을 조작하는 상업주의 의 위험, 예술과 매체 속에서 내러티브를 통해 통용 되는 사회적 관계 내에 파생되는 인간의 감정에 대 한 서술과 표현은 왜곡되어서는 안 된다.
New developments in the determination of the structure of complex organic molecules (1969)

INTRODUCTION There can be no doubt that nowadays determinations of the structure of organic molecules can only be carried out economically, when automatic single crystal diffractometers are used. Such a machine collects more data in a fortnight than a hardworking man in many months. But it is not only the speed and the convenience, but also the inherent accuracy of the measurement which counts. Several diffractometers of different type and construction are available and some laboratories have already gained considerable experience in using them. I do not intend to discuss the different principles; my paper will be restricted to the most general instrument, i.e. to the four-circle diffractometer. This instrument permits the measurement of the full three-dimensional array of reflections with one crystal setting. If desired, the measurements can even be made on an Unoriented crystal. My report will concentrate on our experience with these instruments over the last few years.
P0142 / #1789: RELATIONSHIP BETWEEN UNBALANCED SOLUTIONS AND ACUTE KIDNEY INJURY DURING FLUID RESUSCITATION IN CHILDREN WITH SEPSIS (2021)

Aims & Objectives: To evaluate outcomes of patients with sepsis and septic shock who receive fluids resuscitation with balanced and unbalanced solutions in middle-income country. Methods: An observational, analytical cohort study with propensity score matching in children admitted to pediatric critical care unit, who required fluid boluses due to hemodynamic instability within the first 48 hours after admission. Results: Out of the 1,074 admissions during the study period, 99 patients had sepsis and septic shock. Acute kidney injury was seen less frequently in children who received a balanced solution than in those who received an unbalanced solution (19.7% vs 24.6% p=0.006 ORa, 0.75; 95% CI, 0.65-0.87) adjusted for disease severity. In addition, the group who received balanced solutions had less need for CRRT (3.3 % vs 6.5%; p=0.02 ORa 0.48; 95% CI, 0.36-0.64) and stay at PICU (6 days RIQ 4.4-20.2 vs 10.2 days RIQ 4.7-26;p<0.001) than the group with unbalanced solutions. We found no difference in the frequency of metabolic acidosis (p=0.37), hyperchloremia (p=0.11) and mortality (p=0.25) between the two groups. Conclusions: In children with sepsis-associated organ dysfunction and septic shock, the use of unbalanced solutions for fluid resuscitation is associated with a higher frequency of acute kidney injury, a greater need for continuous renal support and more stay at PICU compared to the use of balanced solutions in middle-income countries.
Effect of size and charge asymmetry on aggregation kinetics of oppositely charged nanoparticles (2019)

We report a theoretical and experimental study of the aggregation kinetics of oppositely charged nanoparticles. Kinetic Monte Carlo simulations are performed for symmetric, charge-asymmetric and size-asymmetric systems of oppositely charged nanoparticles. Simulation results show that both the weight and number average aggregate size kinetics exhibit power law scaling with different exponents for small and intermediate time of evolution. The qualitative behavior of the symmetric and the size asymmetric system are the same, but the charge asymmetric system shows anomalous behavior for intermediate to high particle concentrations. We also observe a strong dependence of power law exponents on the particle concentration. Radius of gyration of the cluster that indicates how nanoparticles inside a cluster are distributed around the center of mass of the cluster shows a non-monotonic time evolution with pronounced peak at higher particle concentration. The dependence of particle concentration on aggregation kinetics as observed by predictive numerical simulation is further verified experimentally by monitoring the time evolution of aggregate size of nanoparticles assemblies of Poly (methacrylic acid) (PMMA) nanoparticles functionalized with oppositely charged ligands. These size and charge tunable asymmetric polymeric nanoparticles were synthesized by modified miniemulsion technique. The integrated approach for studying nanoparticles aggregation as described here renders new insights into super structure formation and morphology optimization which can be potentially useful in the design of new materials, such as organic photovoltaics.
A protocol for anonymous communication over the Internet (2000)

ABSTRACT With the growth and a eptan e of the Internet, there has been in reased interest in maintaining anonymity in the network. This paper presents a new proto ol for initiator anonymity alled Hordes, whi h uses forwarding me hanisms similar to those used in previous proto ols for sending data, but is the rst proto ol to make use of the anonymity inherent in multi ast routing to re eive data. We show this results in shorter transmission laten ies and requires less work of the proto ol parti ipants, in terms of the messages pro essed. We also present a omparison of the se urity and anonymity of Hordes with previous proto ols, using the rst quantitative de nition of anonymity and unlinkability. Our analysis shows that Hordes provides anonymity in a degree similar to that of Crowds and Onion Routing, but also that Hordes has numerous performan e advantages.
Water quality monitoring for coupled food, energy, and water systems (2017)

The focus is on generating real time data for predictive models of food, energy, and water (FEW) systems. It is hypothesized that stressors affecting a FEW system universally impact the water quality of the system. Conversely, fine grain temporal and spatial data describing the water quality of a FEW system can be used to locate system stressors. A high level, predictive model of a FEW system is presented. It is noted that the dynamics of the system are driven by steady state operating characteristics and system stressors. An approach to generation of fine grained spatial temporal water quality data is discussed and an archetypical element of a sensor array is fabricated. The archetypical micro‐controlled sensor element is experimentally evaluated. The results are applied to determining the characteristics necessary of an element of a sensor arrays that is to be used in the prediction of the dynamics of a FEW system. © 2017 American Institute of Chemical Engineers Environ Prog, 37: 165–171, 2018
Prenatal Exposure to Air Pollution, Maternal Psychological Distress, and Child Behavior (2013)

Maternal demoralization during pregnancy appears to have a greater effect on child neurobehavioral development among children who experienced high prenatal PAH exposure. The results provide the first evidence of an interaction between prenatal exposure to maternal demoralization and air pollution on child neurobehavioral development, indicating the need for a multifaceted approach to the prevention of developmental problems in children.
Redox Kinetics for Ferrocene Groups Immobilized in Impermeable and Permeable Self-Assembled Monolayers (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRedox Kinetics for Ferrocene Groups Immobilized in Impermeable and Permeable Self-Assembled MonolayersLisa A. Hockett and Stephen E. CreagerCite this: Langmuir 1995, 11, 6, 2318–2321Publication Date (Print):June 1, 1995Publication History Published online1 May 2002Published inissue 1 June 1995https://pubs.acs.org/doi/10.1021/la00006a077https://doi.org/10.1021/la00006a077research-articleACS PublicationsRequest reuse permissionsArticle Views251Altmetric-Citations38LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (3)»Supporting Information Supporting Information Get e-Alerts
Industrial use of a real-time optical inspection system (1988)

Real-time optical inspection techniques are discussed and implemented on laboratory systems. Specifically, we show how Fourier transform and Hough transform data can be used in an industrial inspection application. We also discuss how a 1-D synthetic discriminant function is used for label inspection. Real-time optical Hough transform inspection data using a 2-D spatial light modulator is presented and discussed. A color liquid crystal television (LCTV) is used as the input transducer to provide real-time data. New methods to process color image data on color LCTVs are detailed. A new high speed acoustooptic architecture to generate Hough transform slices is also detailed. A specific product inspection case study is discussed.
Broad-Spectrum Antibiotic Treatment and Subsequent Childhood Type 1 Diabetes: A Nationwide Danish Cohort Study (2016)

Redemption of broad-spectrum antibiotics during infancy is associated with an increased risk of childhood type 1 diabetes in children delivered by cesarean section.
Interconnect Layout Sensitivity and Yield Prediction (2007)

Abstract Layout sensitivity, a measure of vulnerability to yield loss, typically takes several days to compute for a modern VLSI design. In this article, the authors present and demonstrate a new stochastic model that can significantly expedite the process. The model is based on simple IC layout parameters including wire width, wire spacing, and channel density. The authors explain how they derived the model and how it compares to actual data. They also discuss the causes and effects of open and short defects and define the concepts of critical area and layout sensitivity.
Supplementary Figure Legend from First-in-Human Phase I Trial of Two Schedules of OSI-930, a Novel Multikinase Inhibitor, Incorporating Translational Proof-of-Mechanism Studies (2023)

&lt;p&gt;PDF file - 41K&lt;/p&gt;
Principals and Contractors (1996)

The HSE Act 1992 applies to all New Zealand workplaces. The law emphasizes systematic management of health and safety at work and applies to all employers, principals, employees and those who are in a position to manage hazards.
Interoceptive sensitivity predicts sensitivity to the emotions of others (2014)

Some theories of emotion emphasise a close relationship between interoception and subjective experiences of emotion. In this study, we used facial expressions to examine whether interoceptive sensibility modulated emotional experience in a social context. Interoceptive sensibility was measured using the heartbeat detection task. To estimate individual emotional sensitivity, we made morphed photos that ranged between a neutral and an emotional facial expression (i.e., anger, sadness, disgust and happy). Recognition rates of particular emotions from these photos were calculated and considered as emotional sensitivity thresholds. Our results indicate that participants with accurate interoceptive awareness are sensitive to the emotions of others, especially for expressions of sadness and happy. We also found that false responses to sad faces were closely related with an individual's degree of social anxiety. These results suggest that interoceptive awareness modulates the intensity of the subjective experience of emotion and affects individual traits related to emotion processing.
AVO polarization and hodograms: AVO strength and polarization product (2003)

Abstract An alternative approach to identifying amplitude-variation-with offset (AVO) anomalies is to consider the AVO polarization in the AVO intercept–AVO gradient (A-B) plane. This method does not require deviations or separations from a background trend exhibited in traditional crossplots such as intercept-gradient (A-B) or near trace–far trace (N-F). A benefit of the hodogram or polarization method is that the wavelet is taken into consideration. Crossplotted intercept and gradient are polarized along a “background trend” for nonanomalous events and atangles different from the “background trend” for anomalous events. This allows recognition of anomalous behavior otherwise buried in a background. Attributes resulting from this methodology include (1) the polarization angle, (2) the polarization angle difference, (3) the AVO strength, (4) the polarization product, and (5) the linear-correlation coefficient. These different attributes can then be used to enhance AVO interpretation. Synthetic modeling for a succession of gas and brine layers encased in shale units indicates that the method can potentially be an effective hydrocarbon indicator. Application of the method to a real seismic dataset shows polarization anomalies associated with hydrocarbons.
ChemInform Abstract: A New Approach to Aminoaromatic Thiols: Synthesis of 6‐Amino‐2‐naphthalenethiol. (1988)

Abstract The hydroxynaphthyl methyl ketone (I) reacts with the thiocarbamoyl chloride (II) to produce the O‐naphthyl thiocarbamate (III) which is thermally isomerized, forming the S‐naphthyl derivative (IV).
The Fgf8 signal causes cerebellar differentiation by activating the Ras-ERK signaling pathway (2004)

The mes/metencephalic boundary (isthmus) is an organizing center for the optic tectum and cerebellum. Fgf8 is accepted as a crucial organizing signal. Previously, we reported that Fgf8b could induce cerebellum in the mesencephalon, while Fgf8a transformed the presumptive diencephalon into mesencephalon. Since lower doses of Fgf8b exerted similar effects to those of Fgf8a, the type difference could be attributed to the difference in the strength of the signal. It is of great interest to uncover mechanisms of signal transduction pathways downstream of the Fgf8 signal in tectal and cerebellar development, and in this report we have concentrated on the Ras-ERK pathway. In normal embryos, extracellular-signal-regulated kinase (ERK) is activated at the site where Fgf8 mRNA is expressed. Fgf8b activated ERK while Fgf8a or a lower dose of Fgf8b did not activate ERK in the mes/metencephalon. Disruption of the Ras-ERK signaling pathway by a dominant negative form of Ras (RasS17N) changed the fate of the metencephalic alar plate from cerebellum to tectum. RasS17N canceled the effects of Fgf8b, while co-transfection of Fgf8a and RasS17N exerted additive effects. Disruption of Fgf8b, not Fgf8a, by siRNA resulted in posterior extension of the Otx2 expression domain. Our results indicate that the presumptive metencephalon receives a strong Fgf8 signal that activates the Ras-ERK pathway and differentiates into the cerebellum.
Volumetric imaging of the intraocular propagation medium using differential OTF wavefront sensing (2013)

Differential OTF (dOTF) is is a new image-based non-iterative technique for measuring the complex pupil field. When used with a collection of point sources that exhibit position-dependent PSFs, dOTF allows the 3-D tomographic reconstruction of transmission and aberrating structures between the source and the camera. We explore the potential of using dOTF with a pattern of laser spots projected onto the retina to map the 3-D complex transmission between the cornea to some distance into the vitreous. We present the concept, systems-level analysis, simulations, and initial laboratory experiments to validate this approach.
Stability of the strahl and solar burst electron distribution function and its dynamics (2012)

The so-called “fan” instability of the strahl electron distribution as well as of the plateau-like distribution of the solar burst electrons formed due to excitation of Langmuir waves is discussed. It is shown that this instability can be an effective mechanism of the pitch angle diffusion of these populations of electrons in the solar wind.