gebhart/patrepeval huggingface dataset:
The Literary Criticism of John Middleton Murry (1955)

To Remember the literary criticism of John Middleton Murry only as the “Inner Voice” praising the effort to “Muddle Through,” as T. S. Eliot has characterized it, is to ignore the comprehensive, largely concrete system of literary evaluation which preceded the later doctrine of romanticism. Unfortunately for contemporary literary criticism, most critics of Murry have seen fit to concentrate on what Murry wrote after he began to apply an externally-formulated religious or philosophical theory to literature, or have interpreted the early work in the light of that which followed. Too many who have remembered The Mystery of Keats and Heroes of Thought have forgotten the positive virtues of The Problem of Style and Countries of the Mind . And very few remember that Murry, developing an aesthetic theory similar to Eliot's “objective correlative,” used such a concept as the basic assumption in a consistent system of practical literary criticism. By making a more or less arbitrary distinction between the work primarily concerned with literature per se and that which followed, I believe that it is possible to discover many valuable insights and concepts which can have, or have had, validity for literary criticism today.
Spectrum continuity based routing algorithm for flexible grid optical networks (2015)

Spectrum-sliced elastic optical path networks (SLICE) can maximize spectral resource utilization by using a fine granular spectrum range unit, called frequency slot, and allowing that multiple slots be assigned to lightpaths. The Routing and Spectrum Assignment (RSA) algorithm has a direct influence on the spectral resource utilization. We propose in this paper a novel routing algorithm, referred to as Spectrum Continuity based Shortest Path (SCSP). The SCSP finds a route with the lowest cost based on information of the link length and spectrum continuity. In all simulations, some effects of physical layer are considering as ASE noise, optical amplifier gain and ASE saturation in the amplifiers. The modulation formats are selected during the RSA process to optimize the spectrum resource utilization. We compared the performance of our proposal through simulation with the Shortest Path (SP) and Minimum Hop (MH) routing algorithms for three different network topologies.
Topology of the hog intrinsic factor receptor in the intestine. (1981)

The intrinsic factor receptor was isolated from Triton X-100 extract of hog ileal mucosa using affinity chromatography on intrinsic factor bound to cobalamin-Sepharose. We verified that the receptor contains two subunits, alpha and beta. The purified receptor located in the detergent micelle was radioiodinated. The alpha subunit was labeled and dissociated from the receptor. When the receptor was immobilized on intrinsic factor cobalamin-Sepharose, the part of the receptor which binds intrinsic factor evidently faces the gel and the rest faces outward. When such gel-bound pure receptor was iodinated, the beta subunit was labeled. Iodination of the micellar cobalamin-intrinsic factor receptor complex also caused labeling of the beta subunit. This was interpreted as being due to a conformational change in the receptor affected by the binding of the substrate cobalamin-intrinsic factor, exposing groups accessible to iodination. The beta subunit was found to be hydrophobic, but the alpha subunit was soluble in phosphate buffer without detergent. The receptor was liberated from intestinal mucosa by papain treatment. The enzyme seems to solubilize an intrinsic factor-binding part of the receptor, apparently a part of the alpha subunit. The liberated papain-alpha was purified by affinity chromatography. In gel filtration, it seemed to occur in dimeric form, but its true Mr = 45,000, according to findings in sodium dodecyl sulfate-electrophoresis. In the light of the findings, the topology of the receptor is suggested to be as follows: the alpha subunit binding intrinsic factor faces out and the hydrophobic beta subunit faces in.
<title>Sensory phenomena and measurement instrumentation for smart structures and materials</title> (1998)

This conference focuses on sensory mechanisms in smart material systems, methods for the instrumentation of integrated smart structural systems, and techniques for the characterization of smart or designed materials that are substantially different from methods used to characterize more conventional materials. In this paper, an overview of the purpose of the conference will be provided describing its place within smart structures research, the conference structure will be discussed, and some of the conference papers of note will be previewed.
Supplementary Figure from Radioimmunotherapy Targeting Delta-like Ligand 3 in Small Cell Lung Cancer Exhibits Antitumor Efficacy with Low Toxicity (2023)

Supplementary Figure from Radioimmunotherapy Targeting Delta-like Ligand 3 in Small Cell Lung Cancer Exhibits Antitumor Efficacy with Low Toxicity
PARFAIT: A new scheduler framework supporting heterogeneous Xen-ARM schedulers (2011)

In recent consumer electronics devices, virtualization is widely adopted for diverse reasons such as enhanced reliability, stronger security and better user customizability. Recent CE virtual machines require not only diverse functionalities of GPOS, but also real-time performance of RTOS. However, the current hypervisor-based virtual machine monitors cannot sufficiently support both RTOS and GPOS at the same time. The reason is that the current hypervisor scheduler is biased to only one kind of guest OS and it cannot support heterogeneous schedulers. Therefore, this paper proposes a new scheduler architecture, PARFAIT for both RT and GP guest OSs. Our new scheduler enables to guarantee CPU bandwidth for RTOS and provides fairness among GPOSs using hierarchical structure.
Synthesizing Omnidirectional Antenna Patterns, Received Power and Path Loss from Directional Antennas for 5G Millimeter-Wave Communications (2015)

Omnidirectional path loss models are vital for radiosystem design in wireless communication systems, as they allow engineers to perform network simulations for systems with arbitrary antenna patterns. At millimeter-wave frequencies, channel measurements are frequently conducted using steerable highgain directional antennas at both the transmitter and receiver to make up for the significant increase in free space path loss at these frequencies compared to traditional cellular systems that operate at lower frequencies. The omnidirectional antenna pattern, and resulting omnidirectional received power must therefore be synthesized from many unique pointing angles, where the transmit and receive antennas are rotated over many different azimuth and elevation planes. In this paper, the equivalent omnidirectional antenna pattern and omnidirectional received power are synthesized by summing the received powers from all measured unique pointing angles obtained at antenna halfpower beamwidth step increments in the azimuth and elevation planes, and this method is validated by demonstrating that the synthesized omnidirectional received power and path loss are independent of antenna beamwidth, through theoretical analyses and millimeter-wave propagation measurements using antennas with different beamwidths. The method in this paper is shown to provide accurate results while enhancing the measurement range substantially through the use of directional antennas.
A mouse model of miR-96, miR-182 and miR-183 misexpression implicates miRNAs in cochlear cell fate and homeostasis (2018)

Germline mutations in Mir96, one of three co-expressed polycistronic miRNA genes (Mir96, Mir182, Mir183), cause hereditary hearing loss in humans and mice. Transgenic FVB/NCrl- Tg(GFAP-Mir183,Mir96,Mir182)MDW1 mice (Tg<sup>1MDW</sup>), which overexpress this neurosensory-specific miRNA cluster in the inner ear, were developed as a model system to identify, in the aggregate, target genes and biologic processes regulated by the miR-183 cluster. Histological assessments demonstrate Tg<sup>1MDW/1MDW</sup> homozygotes have a modest increase in cochlear inner hair cells (IHCs). Affymetrix mRNA microarray data analysis revealed that downregulated genes in P5 Tg<sup>1MDW/1MDW</sup> cochlea are statistically enriched for evolutionarily conserved predicted miR-96, miR-182 or miR-183 target sites. ABR and DPOAE tests from 18 days to 3 months of age revealed that Tg<sup>1MDW/1MDW</sup> homozygotes develop progressive neurosensory hearing loss that correlates with histologic assessments showing massive losses of both IHCs and outer hair cells (OHCs). This mammalian miRNA misexpression model demonstrates a potency and specificity of cochlear homeostasis for one of the dozens of endogenously co-expressed, evolutionally conserved, small non-protein coding miRNA families. It should be a valuable tool to predict and elucidate miRNA-regulated genes and integrated functional gene expression networks that significantly influence neurosensory cell differentiation, maturation and homeostasis.
Facile Approach to Conductive Polymer Microelectrodes for Flexible Electronics (2021)

Conductive polymers have been intensively investigated as materials for electrodes in flexible electronics due to their favorable biocompatibility and reliable electrochemical stability. Nevertheless, patterning of conductive polymers for the fabrication of devices and in various electronics applications confronts multifarious limitations and challenges. Here, we present a simple but efficient strategy to obtain conductive polymer microelectrodes via utilization of surface-tension-confined liquid patterns. This method shows universality for various oxidizers and conductive polymers, high resolution, stability, and favorable compatibility with different surfaces and materials. The developed method has been demonstrated for creating conductive polymer microelectrodes with a customized reaction process, defined geometry, and flexible substrates. The obtained microelectrodes were assembled into flexible capacitive sensors. Thus, the method realizes a facile approach to conductive polymer microelectrodes for flexible electronics, biomedical applications, human activity monitors, and electronic skin.
Performance of dithiocarbamate-type flocculant in treating simulated polymer flooding produced water (2011)

从聚合物泛滥的生产的水是困难的由于它的高聚合物集中，高粘性，和使乳化的特征对待。dithiocarbamate 凝聚剂， DTC (T403 ) ，被作为 Jeffamine-T403 知道的终止胺的 polyoxypropane 醚混合物准备。产品被红外系列和元素的分析描绘。有 Fe2+ 的 DTC 代理人 chelating 生产了一个网络聚合物矩阵，它高效地捕获了并且搬迁油微滴。油移动由在有 0 的模仿的生产的水上絮凝， 200， 500， 900 mg/L 部分， hydrolyzed polyacrylamide (HPAM ) 在废水为 DTC (T403 ) 剂量的有效性和 HPAM 和 Fe2+ 离子的集中的方面被调查。当 DTC (T403 ) 剂量比 20 mg/L 低时，结果证明 HPAM 在油移动效率上有否定影响。然而，当 DTC (T403 ) 剂量到达了 30 mg/L 时，在有 HPAM 的不同集中的测试样品的剩余油集中都在 10 mg/L 下面减少了。在起始的废水的 Fe2+ 的集中在 212 mg/L 的范围在油移动上有细微效果。当 Fe3+ 不能在絮凝的条件下面与 DTC 反应，结果证明 Fe3+ 不能代替 Fe2+ 被使用。矿物质盐离子的效果也被调查。
Nanoscale light element identification using machine learning aided STEM-EDS (2020)

Abstract Light element identification is necessary in materials research to obtain detailed insight into various material properties. However, reported techniques, such as scanning transmission electron microscopy (STEM)-energy dispersive X-ray spectroscopy (EDS) have inadequate detection limits, which impairs identification. In this study, we achieved light element identification with nanoscale spatial resolution in a multi-component metal alloy through unsupervised machine learning algorithms of singular value decomposition (SVD) and independent component analysis (ICA). Improvement of the signal-to-noise ratio (SNR) in the STEM-EDS spectrum images was achieved by combining SVD and ICA, leading to the identification of a nanoscale N-depleted region that was not observed in as-measured STEM-EDS. Additionally, the formation of the nanoscale N-depleted region was validated using STEM–electron energy loss spectroscopy and multicomponent diffusional transformation simulation. The enhancement of SNR in STEM-EDS spectrum images by machine learning algorithms can provide an efficient, economical chemical analysis method to identify light elements at the nanoscale.
Secretion of N- and O-linked Glycoproteins from 4T1 Murine Mammary Carcinoma Cells (2016)

Breast cancer is one of the most common cancers that affect women globally and accounts for ~23% of all cancers diagnosed in women. Breast cancer is also one of the leading causes of death primarily due to late stage diagnoses and a lack of effective treatments. Therefore, discovering protein expression biomarkers is mandatory for early detection and thus, critical for successful therapy. Two-dimensional electrophoresis (2D-E) coupled with lectin-based analysis followed by mass spectrometry were applied to identify potential biomarkers in the secretions of a murine mammary carcinoma cell line. Comparisons of the protein profiles of the murine 4T1 mammary carcinoma cell line and a normal murine MM3MG mammary cell line indicated that cadherin-1 (CDH), collagenase 3 (MMP-13), Viral envelope protein G7e (VEP), Gag protein (GAG) and Hypothetical protein LOC433182 (LOC) were uniquely expressed by the 4T1 cells, and pigment epithelium-derived factor (PEDF) was exclusively secreted by the MM3MG cells. Further analysis by a lectin-based study revealed that aberrant O-glycosylated CDH, N-glycosylated MMP-13 and LOC were present in the 4T1 medium. These differentially expressed N- and O-linked glycoprotein candidates, which were identified by combining lectin-based analysis with 2D-E, could serve as potential diagnostic and prognostic markers for breast cancer.
A fragment of anthrax lethal factor delivers proteins to the cytosol without requiring protective antigen (2003)

Anthrax protective antigen (PA) is a 735-aa polypeptide that facilitates the exit of anthrax lethal factor (LF) from the endosome to the cytosol where the toxin acts. We recently found, however, that a fusion protein of the detoxified N-terminal domain of lethal factor (LFn) with a foreign peptide could induce CD8 T cell immune responses in the absence of PA. Because CD8 T cells recognize peptides derived from proteins degraded in the cytosol, this result suggests that lethal factor may be capable of entering the cytosol independently of PA. To investigate this further, the intracellular trafficking of an LFn-enhanced green fluorescent protein fusion protein (LFn-GFP) in the presence or absence of PA was examined by using confocal microscopy. LFn-GFP is able to enter the cytosol without PA. Moreover, it efficiently colocalizes with the proteosome 20s subunit, which degrades proteins into peptides for presentation to CD8 T cells by the MHC class I pathway. We further demonstrate that in the presence of an immune adjuvant LFn fusion protein without PA is able to effectively elicit anti-HIV cytotoxic T lymphocyte in inbred mice. These results indicate that LFn may be used without PA in a protein vaccine as a carrier to deliver antigens into the cytosol for efficient induction of T lymphocyte responses. Furthermore, these results enable us to propose a modified molecular mechanism of anthrax lethal toxin.
Tophaceous pseudogout of the sternoclavicular joint. (1999)

Tophaceous pseudogout of the sternoclavicular joint.K M Richman, R D Boutin, L M Vaughan, P Haghighi and D ResnickAudio Available | Share
Temperature and Wavelength Insensitive Miniature Diode-End-Pumped Nd:YAG Laser (1998)

The wavelength of laser diodes change with an approximate rate of 0.25 nm/ °C, mainly due to the change in band gap with temperature. The wavelength change causes absorption length variation of the diode light in the laser crystal. This in turn induces output energy variation with temperature and demands diode temperature stabilization. In diode-pumped Nd:YAG systems this requirement (1) is below ± 4 °C.
The amplitude of the coherent backscattering intensity peak for discrete random media: Effect of packing density (2010)

The amplitude of the coherent backscattering intensity peak is computed for a medium composed of densely packed, randomly positioned particles. The cyclical component of the Stokes reflection matrix at exactly the backscattering direction is expressed in terms of the ladder component, and the ladder component is rigorously computed by numerically solving the vector radiative transfer equation. The effect of packing density is accounted for by multiplying the single-scattering Mueller matrix by the static structure factor computed in the Percus-Yevick approximation. It is shown that increasing packing density can substantially reduce the amplitude of the copolarized coherent backscattering peak, especially for smaller particles, and can make it significantly lower than 2. The effect of packing density on the amplitude of the cross-polarized peak is significantly weaker.
Functional studies of eppin (2011)

Our laboratory has characterized EPPIN [epididymal protease inhibitor; SPINLW1] as a novel gene on human chromosome 20q12-13.2, which encodes a cysteine-rich protein of 133 amino acids with a calculated molecular mass of 15.283 kDa, containing both Kunitz-type and WAP (whey acidic protein)-type four-disulfide core consensus sequences. Eppin is secreted by Sertoli cells in the testis and epididymal epithelial cells; it is predominantly a dimer, although multimers often exist, and in its native form eppin is found on the human sperm surface complexed with LTF (lactotransferrin) and clusterin. During ejaculation SEMG (semenogelin) from the seminal vesicles binds to the eppin protein complex, initiating a series of events that define eppin's function. Eppin's functions include (i) modulating PSA (prostate-specific antigen) enzyme activity, (ii) providing antimicrobial protection and (iii) binding SEMG thereby inhibiting sperm motility. As PSA hydrolyses SEMG in the ejaculate coagulum, spermatozoa gain progressive motility. We have demonstrated that eppin is essential for fertility because immunization of male monkeys with recombinant eppin results in complete, but reversible, contraception. To exploit our understanding of eppin's function, we are developing compounds that inhibit eppin-SEMG interaction and mimic anti-eppin, inhibiting sperm motility. These compounds should have potential as a male contraceptive.
A Longitudinal Operant Assessment of Cognitive and Behavioural Changes in the HdhQ111 Mouse Model of Huntington’s Disease (2016)

Huntington's disease (HD) is characterised by motor symptoms which are often preceded by cognitive and behavioural changes, that can significantly contribute to disease burden for people living with HD. Numerous knock-in mouse models of HD are currently available for scientific research. However, before their use, they must be behaviourally characterised to determine their suitability in recapitulating the symptoms of the human condition. Thus, we sought to longitudinally characterise the nature, severity and time course of cognitive and behavioural changes observed in HdhQ111 heterozygous knock-in mice.To determine changes in cognition and behaviour an extensive battery of operant tests including: fixed ratio, progressive ratio, the five choice serial reaction time task and the serial implicit learning task, were applied longitudinally to HdhQ111 and wild type mice. The operant test battery was conducted at 6, 12 and 18 months of age. Significant deficits were observed in HdhQ111 animals in comparison to wild type animals in all operant tests indicating altered cognition (attentional and executive function) and motivation. However, the cognitive and behavioural deficits observed were not shown to be progressive over time in the longitudinal testing paradigm that was utilised. The results therefore demonstrate that the HdhQ111 mouse model of HD reflects some features of the cognitive and behavioural changes shown in the human condition of HD. Although, the cognitive and behavioural deficits demonstrated were not shown to be progressive over time.
Detecting backdoors (2000)

Backdoors are often installed by attackers who have compromised a system to ease their subsequent return to the system. We consider the problem of identifying a large class of backdoors, namely those providing interactive access on non-standard ports, by passively monitoring a site&amp;apos;s Internet access link. We develop a general algorithm for detecting interactive traffic based on packet size and timing characteristics, and a set of protocol-specific algorithms that look for signatures distinctive to particular protocols. We evaluate the algorithms on large Internet access traces and find that they perform quite well. In addition, some of the algorithms are amenable to prefiltering using a stateless packet filter, which yields a major performance increase at little or no loss of accuracy. However, the success of the algorithms is tempered by the discovery that large sites have many users who routinely access what are in fact benign backdoors, such as servers running on nonstandard ports not to hide, but for mundane administrative reasons. Hence, backdoor detection also requires a significant policy component for separating allowable backdoor access from surreptitious access. 1
Emerging evidence for the role of an endorectal balloon in prostate radiation therapy (2012)

Purpose: To reassess and update the role of an endorectal balloon (ERB) in prostate radiotherapy (RT) based on emerging evidence by reviewing various aspects of treatment methodologies and clinical outcomes. Methods and materials: A literature review based on a PubMed/MEDLINE database search using keywords such as: ERB, prostate RT, toxicities, real-time, image-guided radiotherapy (IGRT), radiofrequency-guided radiotherapy (RGRT), and inter- and intrafraction prostate motion for articles published over the past two years. Ten articles were identified and subdivided into three categories: (I) Issue of Motion, (II) Dosimetry, (III) Clinical Outcomes. Results: With the advent of real-time prostate tracking, analysis of intrafraction motion as a function of treatment time for patients treated with a daily-ERB was performed and revealed an overall reduction in 3D prostate motion, especially in the anterior-posterior direction. Two different groups of authors found that this reduction in intrafraction prostate motion allowed for tighter internal margins. Dosimetric studies showed overall improved dose distributions which for proton therapy were maximized when using ERBguided range verification for anteriorly oriented beams. Clinical outcomes showed favorable early GI toxicities however late toxicity results are still awaited. Conclusions: Utilizing a daily-ERB shows favorable early GI toxicity as well as reduced prostate intrafraction motion based on real-time tracking data. Reduced intrafraction motion improves the feasibility to use anteriorly oriented proton beams, which may further improve dosimetry.
Nitrogen uptake and assimilation by corn roots (1977)

In corn roots, uN-labelled ammonium was rapidly assimilated into glutamine, glutamic acid, and aspartic acid in this order in a short time.uN-labelled nitrate was assimilated into amino acids in almost the same way with ammonium, but at lower uN value.The inhibitory effect oflow temperature was more drastic on the nitrate uptake than on the ammonium uptake.Newly absorbed ammonium nitrogen was more utilizable for the growth of root top than nitrate nitrogen.