gebhart/patrepeval huggingface dataset:
Optimal Portfolio Choice under Heterogeneous Beliefs (2000)

Abstract This paper analyzes how an investor who is convinced that he can “beat the market” should behave when the equilibrium price process is endogenous. The investor's optimal portfolio is shown to consist of three components: (1) a tangency portfolio, (2) a hedge portfolio against changes in the market's valuation of securities, and (3) a hedging position against changes in the divergence between the investor's and the market's beliefs. The sign and magnitude of this third component will depend on investor preferences and on the divergence in the investor's and the market's quality of information. A numerical example illustrates that the effect of heterogeneous beliefs on optimal portfolio allocations can be significant. JEL classification codes: G11, G14.
Blood Lactate in the Prognosis of Various Forms of Shock (1971)

From the Center for the Study of Trauma, University of Maryland School of Medicine, Baltimore, Maryland 21201
Studies on Methylglyoxal Bis(guanylhydrazone)1 Analogs. II. Structural Variations on Methylglyoxal Bis(guanylhydrazone)2 (1963)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStudies on Methylglyoxal Bis(guanylhydrazone)1 Analogs. II. Structural Variations on Methylglyoxal Bis(guanylhydrazone)2Fred Baiocchi, C. C. Cheng, W. J. Haggerty Jr., Leland R. Lewis, T. K. Liao, Wayne H. Nyberg, Darrell E. O'Brien, and Eugene G. PodrebaracCite this: J. Med. Chem. 1963, 6, 4, 431–435Publication Date (Print):July 1, 1963Publication History Published online1 May 2002Published inissue 1 July 1963https://doi.org/10.1021/jm00340a020RIGHTS & PERMISSIONSArticle Views199Altmetric-Citations32LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (498 KB) Get e-Alerts Get e-Alerts
Reviews of "Differential effects of antiseptic mouth rinses on SARS-CoV-2 infectivity in vitro" (2021)

Reviews of "Di erential e ects of antiseptic mouth rinses
Chronic Total Occlusion of the Left Main Coronary Artery. (1997)

We report 3 patients with chronic total occlusion of the left main coronary artery, which is considered to be very rare. In all three cases, coronary arteriograms showed a total occlusion of the left main coronary artery with good collaterals from the intact right coronary arteries. All of the patients underwent successful coronary artery bypass surgery; two of the cases were followed up for more than 10 years after the surgery. The Japanese literature is reviewed, and a comparison of foreign and Japanese cases is discussed.
Laser beam cleanup with photorefractive two-beam coupling (1995)

The effectiveness of laser beam cleanup with photorefractive two-beam coupling is evaluated. We compare the measured effectiveness of the method with that of spatial filtering and find that the method works well for a highly aberrated beam approximately 700 times diffraction limited, whereas for moderately aberrated beams the effectiveness of the method is the same as that of spatial filtering.
Measurement of Individual Conductor Tension During Pipe-Type Cable Installation (1969)

Users of pipe cable have a strong economic incentive to space manholes as far apart as possible. To attain this objective, it is necessary to have accurate information on the stresses developed in each conductor during the pulling operation. This paper describes a novel method of measuring tension on each conductor at the pulling head and presents the results obtained in installing about 6 miles (9.7 km) of 1250-kcmil 115-kV pipe-type cable.
Automated flight path planning for virtual endoscopy (1998)

In this paper, a novel technique for rapid and automatic computation of flight paths for guiding virtual endoscopic exploration of three-dimensional medical images is described. While manually planning flight paths is a tedious and time consuming task, our algorithm is automated and fast. Our method for positioning the virtual camera is based on the medial axis transform but is much more computationally efficient. By iteratively correcting a path toward the medial axis, the necessity of evaluating simple point criteria during morphological thinning is eliminated. The virtual camera is also oriented in a stable viewing direction, avoiding sudden twists and turns. We tested our algorithm on volumetric data sets of eight colons, one aorta and one bronchial tree. The algorithm computed the flight paths in several minutes per volume on an inexpensive workstation with minimal computation time added for multiple paths through branching structures (10%-13% per extra path). The results of our algorithm are smooth, centralized paths that aid in the task of navigation in virtual endoscopic exploration of three-dimensional medical images.
The CpG Island Methylator Phenotype: What's in a Name? (2013)

Although the CpG island methylator phenotype (CIMP) was first identified and has been most extensively studied in colorectal cancer, the term "CIMP" has been repeatedly used over the past decade to describe CpG island promoter methylation in other tumor types, including bladder, breast, endometrial, gastric, glioblastoma (gliomas), hepatocellular, lung, ovarian, pancreatic, renal cell, and prostate cancers, as well as for leukemia, melanoma, duodenal adenocarninomas, adrenocortical carcinomas, and neuroblastomas. CIMP has been reported to be useful for predicting prognosis and response to treatment in a variety of tumor types, but it remains unclear whether or not CIMP is a universal phenomenon across human neoplasia or if there should be cancer-specific definitions of the phenotype. Recently, it was shown that somatic isocitrate dehydrogenase-1 (IDH1) mutations, frequently observed in gliomas, establish CIMP in primary human astrocytes by remodeling the methylome. Interestingly, somatic IDH1 and IDH2 mutations, and loss-of-function mutations in ten-eleven translocation (TET) methylcytosine dioxygenase-2 (TET2) associated with a hypermethylation phenotype, are also found in multiple enchondromas of patients with Ollier disease and Mafucci syndrome, and leukemia, respectively. These data provide the first clues for the elucidation of a molecular basis for CIMP. Although CIMP appears as a phenomenon that occurs in various cancer types, the definition is poorly defined and differs for each tumor. The current perspective discusses the use of the term CIMP in cancer, its significance in clinical practice, and future directions that may aid in identifying the true cause and definition of CIMP in different forms of human neoplasia.
Liposome-Encapsulated Ciprofloxacin Is Effective in the Protection and Treatment of BALB/c Mice against Francisella tularensis (1993)

Liposome-Encapsulated Ciprofloxacin Is Effective in the Protection and Treatment of BALB/c Mice against Francisella tularensis Get access Vincent L. Di Ninno, Vincent L. Di Ninno Defence Research Establishment Suffield, Medicine Hat, Canada. Search for other works by this author on: Oxford Academic PubMed Google Scholar John W. Cherwonogrodzky, John W. Cherwonogrodzky Defence Research Establishment Suffield, Medicine Hat, Canada. Reprints or correspondence: Dr. John W. Cherwonogrodzky, Defence Research Establishment Suffield, Box 4000. Medicine Hat, Alberta, Canada, Tl A 8K6. Search for other works by this author on: Oxford Academic PubMed Google Scholar Jonathan P. Wong Jonathan P. Wong Defence Research Establishment Suffield, Medicine Hat, Canada. Search for other works by this author on: Oxford Academic PubMed Google Scholar The Journal of Infectious Diseases, Volume 168, Issue 3, September 1993, Pages 793–794, https://doi.org/10.1093/infdis/168.3.793 Published: 01 September 1993
Staphylococcus aureus sigma B-dependent emergence of small-colony variants and biofilm production following exposure to Pseudomonas aeruginosa 4-hydroxy-2-heptylquinoline-N- oxide (2010)

These results suggest that S. aureus responds to HQNO from P. aeruginosa by forming SCVs and biofilms through SigB activation, a phenomenon that may contribute to the establishment of chronic infections in CF patients.
Molecular Ecology of Listeria monocytogenes : Evidence for a Reservoir in Milking Equipment on a Dairy Farm (2008)

A longitudinal study aimed to detect Listeria monocytogenes on a New York State dairy farm was conducted between February 2004 and July 2007. Fecal samples were collected every 6 months from all lactating cows. Approximately 20 environmental samples were obtained every 3 months. Bulk tank milk samples and in-line milk filter samples were obtained weekly. Samples from milking equipment and the milking parlor environment were obtained in May 2007. Fifty-one of 715 fecal samples (7.1%) and 22 of 303 environmental samples (7.3%) were positive for L. monocytogenes. A total of 73 of 108 in-line milk filter samples (67.6%) and 34 of 172 bulk tank milk samples (19.7%) were positive for L. monocytogenes. Listeria monocytogenes was isolated from 6 of 40 (15%) sampling sites in the milking parlor and milking equipment. In-line milk filter samples had a greater proportion of L. monocytogenes than did bulk tank milk samples (P<0.05) and samples from other sources (P<0.05). The proportion of L. monocytogenes-positive samples was greater among bulk tank milk samples than among fecal or environmental samples (P<0.05). Analysis of 60 isolates by pulsed-field gel electrophoresis (PFGE) yielded 23 PFGE types after digestion with AscI and ApaI endonucleases. Three PFGE types of L. monocytogenes were repeatedly found in longitudinally collected samples from bulk tank milk and in-line milk filters.
Toward elemental analysis of ambient single particles using electrodynamic balance and laser-induced breakdown spectroscopy (2020)

In this article, we present a novel method for the elemental analysis of airborne aerosol particles using electrodynamic balance (EDB) trapping followed by laser-induced breakdown spectroscopy. The setup consists of a newly designed corona-based aerosol charger, double-ring electrodynamic balance trap and optical arrangement for the spectroscopy. Experimental laboratory measurements using the method show that the minimum particle size for successful analysis is 1 µm in diameter, and the minimum airborne concentration is of the order of 1 particle/cm<sup>3</sup>. In addition to the method, we will present results on the charging efficiency of the developed charger and novel stability analysis of the EDB at the charge region. The results from the stability analysis will ease the way toward analyzing submicron particles with the technique.
A 16MB 3.5 inch Ba-Ferrite flexible disk drive with dual track following servo modes (1987)

A large capacity high-speed-access 3.5 inch flexible disk drive has been achieved, using a barium ferrite 3.5 inch flexible disk and newly developed sector servo technology. The flexible disk drive has a 16 megabyte unformatted capacity, a 50 millisecond average seek time and a 3 megabit/second data transfer rate. It can use both concentric track disks for conventional computer systems and spiral track disks for high speed data transfer systems, such as hard disk drive (HDD) back-up, image data storing, and so on.
Reduction of plasmon linewidth in dispersive absorbing media (2020)

The effects of loss on the plasmon resonance peak in dispersive absorbing media are investigated. We find that dispersive loss can lead to narrower plasmon resonances. We also measure the plasmon peak for gold nanospheres embedded in P3HT, poly(3-hexylthiophene), using a dark field microscope.
Abstract 5198: Androgen receptor signaling affects macrophage differentiation in the human prostate cancer microenvironment (2018)

Abstract Increasing evidence from epidemiologic and pathologic studies suggests a role of macrophages in the initiation and progression of prostate cancer (PCa). During PCa development, macrophages (CD68+) are recruited into the human prostate cancer microenvironment, including inflammation-associated M1 and cancer-promoting M2 macrophages. Like other prostate cancer-associated stromal cells, macrophages express the androgen receptor (AR); however, its functionality is not known. CD68+ cells generated in vitro from peripheral white blood cells and PMA activated and IFN and LPS polarized human acute monocytic leukemia THP-1 cells also expressed AR. In these cells AR is an 80KD splice variant, lacking parts of exon 1 and exon 2. AR translocated to the nucleus upon testosterone stimulation, which was counteracted by the AR signaling inhibitor RD162. In vitro generated M1 macrophages expressed the M2 markers CD163 and CD206 upon testosterone stimulation, which was reversed by RD162. AR-ChIP sequencing suggested AR regulated Macrophage Triggering Receptor 1 (TREM1) signaling. Expression of key cytokines (e.g., CCL2, CXCL8, CCL7, IL10, IL1B) involved in TREM1 signaling was upregulated upon testosterone stimulation. Actions of these cytokines is generally associated with a protumor phenotype of macrophages. Conditioned medium from macrophages stimulated with testosterone for 8 hrs resulted in enhanced proliferation and migration of human prostate LNCap and CWRR1 cells. In conclusion, AR signaling might affect differentiation of prostate cancer-associated macrophages into cancer-promoting M2, which affects prostate cancer cell proliferation and migration. Maintaining macrophages in M1 might be a novel mechanism of action of androgen receptor inhibitors. Citation Format: Bianca Cioni, Ekatarina Nevedomskaya, Suzan Stelloo, Monique Melis, Johan van Burgsteden, Jeroen de Jong, Henk van der Poel, Jan Paul de Boer, Wilbert Zwart, Andries M. Bergman. Androgen receptor signaling affects macrophage differentiation in the human prostate cancer microenvironment [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2018; 2018 Apr 14-18; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2018;78(13 Suppl):Abstract nr 5198.
Disease management: a contracting primer. (1996)

This article provides an understanding of the issues and steps that are required for negotiating a disease management contract. Because most of the author's experience derives from representing pharmaceutical companies and other provider driven entities, the tenor of the comments often reflects that perspective on negotiations. This article focuses on disease management contracting whereby a provider network or case manager assumes risk relating to the cost of providing care to a certain type of patient.
Optically Powered Video Camera Link (2007)

We implemented an optically powered video camera connected to a base station at 200 m distance. Power and 100-Mbps data-channel are multiplexed at 810 nm and 1310 nm into a standard 62.5 μm multimode fiber.
Photoreactivity of Polymers with Regioisomeric Cinnamate Side Chains and Their Ability To Regulate Liquid Crystal Alignment (1997)

Photoproduct distribution in films of cinnamate polymers was analyzed to reveal the contribution of both photoisomerization and photodimerization to LC alignment photoregulation. A polymethacrylate with o-cinnamate side chains displayed preferential formation of Z-isomer while the dimerization takes place more favorably for other polymers including poly(vinyl cinnamate). On the basis of the relationship between photoproduct distribution and liquid crystal photoalignment and on the reversibility of the photoinduced reorientation of a liquid crystal, it was concluded that the photoalignment results from the polarization photoisomerization of cinnamate residues in the same manner as that of photochromic moieties like azobenzenes, whereas the (2 + 2) photodimerization plays a role in enhancing the thermal stability of the homogeneous photoalignment.
A Thiacalix[3]pyridine Copper(I) Complex as a Highly Active Catalyst for the Olefin Aziridination Reaction (2008)

Abstract A copper(I) complex with thiacalix[3]pyridine, [Cu(Py3S3)]2(PF6)2, is a competent catalyst for aziridination of olefins. The reaction of styrene (1 equiv) with PhI=NTs (1 equiv) at 20 °C produced N-(p-toluenesulfonyl)-2-phenylaziridine (71%, turnover number = 55) in the presence of 1.2 mol % catalyst under aerobic conditions. The turnover number increased up to 350 with a 0.12 mol % catalyst and a 5:1 styrene/PhI=NTs ratio in 41% yield.
Automated Detection of the Foveal Center Improves SD-OCT Measurements of Central Retinal Thickness (2012)

The automated algorithm designed to detect the foveal center was more accurate in detecting the foveal center than relying on the fixation target of the SD-OCT instrument.
Regulation of the synthesis and activity of thymidine phosphorylase inLactobacillus casei (1991)

Lactobacillus casei cells grown on excess thymine or on folic acid contained low levels of thymidine phosphorylase. On the other hand, thymine starved cells and also cells of a thymidine-monophosphate-kinase-defective mutant grown on excess thymine, possessed derepressed levels. These results suggest that the synthesis of thymidine phosphorylase is regulated by the end product of the thymidine-triphosphate-biosynthetic pathway. L. casei cells lacked 2-deoxyribose-1-phosphate-mutase activity and did not grow on 2-deoxyribose or thymidine as the sole-carbon source. Growth in the presence of thymidine did not result in induction of thymidine-phosphorylase synthesis, probably due to the inability of the cell to convert it to 2-deoxyribose-5-phosphate, which is known to act as an inducer in E. coli cells. Thymidine triphosphate inhibited non-competitively the activity of thymidine phosphorylase. It was also inhibited by dihydrofolic acid.
Oscillating Brownian motion (1978)

An ‘oscillating' version of Brownian motion is defined and studied. ‘Ordinary' Brownian motion and ‘reflecting' Brownian motion are shown to arise as special cases. Transition densities, first-passage time distributions, and occupation time distributions for the process are obtained explicitly. Convergence of a simple oscillating random walk to an oscillating Brownian motion process is established by using results of Stone (1963).
Distributed rendering for multiview parallax displays (2006)

3D display technology holds great promise for the future of television, virtual reality, entertainment, and visualization. Multiview parallax displays deliver stereoscopic views without glasses to arbitrary positions within the viewing zone. These systems must include a high-performance and scalable 3D rendering subsystem in order to generate multiple views at real-time frame rates. This paper describes a distributed rendering system for large-scale multiview parallax displays built with a network of PCs, commodity graphics accelerators, multiple projectors, and multiview screens. The main challenge is to render various perspective views of the scene and assign rendering tasks effectively. In this paper we investigate two different approaches: Optical multiplexing for lenticular screens and software multiplexing for parallax-barrier displays. We describe the construction of large-scale multi-projector 3D display systems using lenticular and parallax-barrier technology. We have developed different distributed rendering algorithms using the Chromium stream-processing framework and evaluate the trade-offs and performance bottlenecks. Our results show that Chromium is well suited for interactive rendering on multiview parallax displays.
<title>Collector-controlled states in charge injection transistors (Invited Paper)</title> (1992)

We review recent theoretical studies of the symmetry properties of charge injection transistors. These studies, based on continuation modeling and transient device simulation, incorporate self-consistently the electron energy and real-space transfer currents over heterojunction interfaces. Inspection of the full device phase—space reveals a variety of instabilities and a striking novelty of multiply-connected current-voltage characteristics. We have found anomalous steady states in which hot-electron injection occurs in the absence of any voltage between the emitter electrodes. In these states, some of which are not only stationary but also stable with respect to small perturbations, the electron heating is due to the fringing field from the collector electrode. Some of the anomalous states break the reflection symmetry in the plane normal to the channel at midpoint. The study elucidates the formation of hot-electron domains in real-space transfer.
Theoretical model of an interleave-chirped arrayed waveguide grating (IC-AWG) (2013)

In this paper, we propose a theoretical model for an Interleave-Chirped Arrayed Waveguide Grating (IC-AWG), modifying the already existing formulation based on Fourier optics. With the IC-AWG is possible to achieve several functionalities in a single device, such as channel demultiplexing, polarization splitting and 90&deg; optical hybrid operation. We also elaborate on the developed model to present a design procedure for the IC-AWG. Finally, the model validation through numerical simulations using real physical parameters obtained from manufactured devices available in the literature is performed.
Selective abrogation of Th1 response by STA-5326, a potent IL-12/IL-23 inhibitor (2006)

The interleukin-12 (IL-12) cytokine induces the differentiation of naive T cells to the T helper cell type 1 (Th1) phenotype and is integral to the pathogenesis of Th1-mediated immunologic disorders. A more recently discovered IL-12 family member, IL-23, shares the p40 protein subunit with IL-12 and plays a critical role in the generation of effector memory T cells and IL-17-producing T cells. We introduce a novel compound, STA-5326, that down-regulates both IL-12 p35 and IL-12/IL-23 p40 at the transcriptional level, and inhibits the production of both IL-12 and IL-23 cytokines. Oral administration of STA-5326 led to a suppression of the Th1 but not Th2 immune response in mice. In vivo studies using a CD4+CD45Rbhigh T-cell transfer severe combined immunodeficiency (SCID) mouse inflammatory bowel disease model demonstrated that oral administration of STA-5326 markedly reduced inflammatory histopathologic changes in the colon. A striking decrease in interferon-gamma (IFN-gamma) production was observed in ex vivo culture of lamina propria cells harvested from animals treated with STA-5326, indicating a down-regulation of the Th1 response by STA-5326. These results suggest that STA-5326 has potential for use in the treatment of Th1-related autoimmune or immunologic disorders. STA-5326 currently is being evaluated in phase 2 clinical trials in patients with Crohn disease and rheumatoid arthritis.