gebhart/patrepeval huggingface dataset:
CASES-99: A Comprehensive Investigation of the Stable Nocturnal Boundary Layer (2002)

The Cooperative Atmosphere–Surface Exchange Study—1999 (CASES-99) refers to a field experiment carried out in southeast Kansas during October 1999 and the subsequent program of investigation. Comprehensive data, primarily taken during the nighttime but typically including the evening and morning transition, supports data analyses, theoretical studies, and state-of-the-art numerical modeling in a concerted effort by participants to investigate four areas of scientific interest. The choice of these scientific topics is motivated by both the need to delineate physical processes that characterize the stable boundary layer, which are as yet not clearly understood, and the specific scientific goals of the investigators. Each of the scientific goals should be largely achievable with the measurements taken, as is shown with preliminary analysis within the scope of three of the four scientific goals. Underlying this effort is the fundamental motivation to eliminate deficiencies in surface layer and turbulent diffusion parameterizations in atmospheric models, particularly where the Richardson number exceeds 0.25. This extensive nocturnal boundary layer (NBL) dataset is available to the scientific community at large, and the CASES-99 participants encourage all interested parties to utilize it. These preliminary analyses show that during nights where weak (< 2 m s−1) surface winds and strong static stability near the surface (exceeding 150 C km−1 to 20 m AGL) might otherwise indicate essentially nonturbulent conditions, that various, sometimes undefined, atmospheric phenomena can generate significant turbulent mixing, and therefore significant turbulent fluxes. In many cases, a jet structure will form in the NBL between 50 and 200 m AGL, resulting in strong shear between the surface and jet maximum. Consequently, though surface winds are weak, turbulence can be a significant feature in the stable NBL. Further, contrary to some previous work studying nocturnal jets over the Great Plains, the wind direction in the jet is often influenced by an inertial oscillation and seldom confined to the southerly quadrant (e.g., the Great Plains low-level jet).
Circuit techniques for a 25 ns 16Kx1 SRAM using address-transition detection (1984)

The authors describe special circuit techniques that have been used to produce a 25-ns HMOS 16K/spl times/1 SRAM. In particular, a new dynamic row-decoder driver, hold-valid-data output driver, and column-decoder driver have been developed. A new memory clear function, called the bulk-write feature, that writes all data locations to the same data as the data-in pin in one long (/spl sime/700 ns) write cycle was also developed. This 16K/spl times/1 SRAM has a die area of 25.3K mil/SUP 2/ (16.3 mm/SUP 2/), and was fabricated using a 2-/spl mu/m double-polysilicon NMOS technology.
Corticotropin-releasing hormone signaling in synovial tissue from patients with early inflammatory arthritis is mediated by the type 1? corticotropin-releasing hormone receptor (2001)

Our findings suggest that CRH signaling, via CRH-R1alpha, may play a role in both the vascular changes and the pathologic mechanisms associated with joint inflammation in human arthritis.
Lithium-Assisted Plastic Deformation of Silicon Electrodes in Lithium-Ion Batteries: A First-Principles Theoretical Study (2011)

Silicon can host a large amount of lithium, making it a promising electrode for high-capacity lithium-ion batteries. Recent experiments indicate that silicon experiences large plastic deformation upon Li absorption, which can significantly decrease the stresses induced by lithiation and thus mitigate fracture failure of electrodes. These issues become especially relevant in nanostructured electrodes with confined geometries. On the basis of first-principles calculations, we present a study of the microscopic deformation mechanism of lithiated silicon at relatively low Li concentration, which captures the onset of plasticity induced by lithiation. We find that lithium insertion leads to breaking of Si-Si bonds and formation of weaker bonds between neighboring Si and Li atoms, which results in a decrease in Young's modulus, a reduction in strength, and a brittle-to-ductile transition with increasing Li concentration. The microscopic mechanism of large plastic deformation is attributed to continuous lithium-assisted breaking and re-forming of Si-Si bonds and the creation of nanopores.
High-Q photonic crystal nanocavities on diamond for quantum electrodynamics (2006)

A slab two-dimensional photonic crystal in diamond is being considered for quantum information processing. In view of the low refractive index of diamond, the question whether a high Q cavity is achievable has to be addressed. Here, various geometrical designs of single point defects and double heterostructures for the formation of high Q nanocavities in diamond are modeled. The highest value of vertical quality factor was achieved in double heterostructures. This result seems to be significant for further consideration of photonic crystals in diamond for quantum electrodynamics applications.
Evaluation of test methods for self-healing concrete with macrocapsules by inter-laboratory testing (2021)

Self-healing of concrete is a promising way to increase the service life of structures. Innovative research is being performed, yet it is difficult to compare results due to a lack of standardised test methods. In the framework of the COST action SARCOS (CA15202) [1] six different interlaboratory tests are being executed, in which different test methods are being evaluated for six self-healing approaches. Here, the results of the inter-laboratory test concerning mortar and concrete with macrocapsules filled with a polyurethane healing agent will be discussed. The specimens were manufactured in one laboratory and then shipped to the other five participating laboratories. All six laboratories evaluated two test methods: a water permeability test and a capillary water absorption test. For the water permeability test, mortar specimens were cracked and afterwards their crack width was controlled using an active control technique. Due to the active crack control, the crack width of 90% of the samples deviated by less than 10 μm from the target of 300 μm. This made it more straightforward to compare the permeability test results, which indicated a similar sealing efficiency for several of the laboratories. For the capillary water absorption test, concrete specimens were cracked in a crack-width-controlled three-point bending test setup without active control after unloading. Compared to the water permeability specimens, there was a lot more variation on the crack width of the capillary water absorption specimens. The variability on the crack width and differences in quality of waterproofing resulted in diverging findings in the capillary water absorption test.
Effects of Vernonia amygdalina on Biochemical and Hematological Parameters in Diabetic Rats (2009)

Subacute toxicity studies were carried out on the fraction of the methanol leaf extract of Vernonia amygdalina in diabetic rats. Nine fractions (F1-F9) were obtained from the MEOH leaf extract of V. amygdalina and screened for antihyperglycemic activity in alloxan-induced diabetic rats. The most potent hypoglycemic fraction (F6) was administered daily to normal and diabetic rats for 28 days at doses of 80, 160 and 320 mg/kg. Blood glucose level, body weight, food and liquid intake, and some biochemical and hematological indices were monitored over the treatment period. At these doses, fraction F6 significantly (p<0.05) increased food intake and body weight and decreased water intake in the diabetic rats. The fraction significantly (p<0.01) decreased the levels of triglycerides, l ow density lipoprotein cholesterol, very low density lipoprotein cholesterol, and increased high density lipoprotein cholesterol level in the diabetic rats. Treatment with fraction F6 (160 and 320 mg/kg) significantly (p<0.05) increased the lymphocyte count and elect rolytes level s bu t lowered the levels of urea and creatinine. The elevated levels of aspartate aminotransferase, alanine aminotransferase and alkaline phosp hatase in the diabetic rat s were significantly (p<0. 01) lowered. The histopathological studies revealed no significant abnormalities in the vital organs in both F6 and chlorpropamide treated rats. These results suggest that fraction F 6 of V. amygdalina is a potent hypoglycemic and hypolipidemic agent which is safe and capable of normalizing biochemical and hematological abnormalities associated with the pathophysiology of diabetes mellitus.
Organotypic Bioelectric Activity in Cultured Reaggregates of Dissociated Rodent Brain Cells (1972)

Complex repetitive-spike or slow-wave discharges can be evoked, and can also occur spontaneously, in small clusters of neurons which reaggregate in vitro after dissociation of cerebral cortex, brainstem, or spinal cord from the fetal mouse. Even after random dispersion in culture, these cells still form functional synaptic networks with bioelectric discharge patterns and pharmacologic sensitivities characteristic of the organ (that is, organotypic).
EVIDENCE THAT CHRONIC HYPERGLYCEMIA IN MICE DOES NOT ADVERSELY AFFECT FETAL ISLET CELL ALLOGRAFT FUNCTION (1989)

Experiences sur souris rendues diabetiques par injection intramusculaire de streptozotocine. L'hyperglycemie n'empeche pas la fonction de cellules d'ilots fœtaux allogreffees. La presence d'une reaction allogenique est un stimulant pour l'angiogenese. Les greffons sont rapidement vascularises
ORGAN DONATION (2001)

In 2000 the number of organ transplants performed fell by 3% while the waiting list numbers rose by 2%. The human consequence of these statistics is that because of the shortage of organs more people who are in need of a transplant are dying. There is no one single reason to why this is happening with the result that the solution may be complex. One initiative to improve the current situation with regards organ donation is a change to legislation, to move from the current system where-by the views of the next of kin are sought prior to donation, to one where consent will be presumed unless the deceased has registered an objection during their lifetime.
FLUAGE DE JOINTS COLLES A L'AIDE DE POLYESTERS ACRYLIQUES DANS LE CAS DE BETONS IMPREGNES (1981)

LES ESSAIS ONT ETE FAITS AVEC DEUX COLLES, DONT UNE CONTENANT UNE RESINE EPOXY SUR DES EPROUVETTES PRISMATIQUES (40X40X80 MM). LES RESULTATS SONT DU MEME ORDRE ; DANS LES DEUX CAS, LES DEFORMATIONS DE FLUAGE SONT FORTEMENT AMORTIES APRES 6 MOIS SOUS UNE CHARGE DE L'ORDRE DE 45 % DE CELLE ENTRAINANT UNE RUPTURE.
ChemInform Abstract: SYNTHESIS AND PROPERTIES OF THE FIRST INTRAMOLECULAR ARENEDIAZONIUM CATION‐CROWN ETHER COMPLEX (1984)

Abstract In Gegenwart von Kronenether addiert das Diazoniumsalz (I) mit Anisol (II) zu einem DiphenyI‐ether‐Derivat (IIIa), das mit IlBr zum Phenol (IIIb) gespalten wird.
Interaction Trap/Two‐Hybrid System to Identify Interacting Proteins (2008)

The yeast two-hybrid method (or interaction trap) is a powerful technique for detecting protein interactions. The procedure is performed using transcriptional activation of a dual reporter system in yeast to identify interactions between a protein of interest (the bait protein) and the candidate proteins for interaction. The method can be used to screen a protein library for interactions with a bait protein or to test for association between proteins that are expected to interact based on prior evidence. Interaction mating facilitates the screening of a library with multiple bait proteins.
Construction of a chimeric intein-containing protein and the search for conditions for its cleavage (2007)

Protein splicing is a post-translational autocatalytic process that results in the excision of an internal peptide (the intein) from a precursor protein and the ligation of the flanking protein sequences (the exteins). The high specificity of intein-mediated excision of protein precursors permits the use of protein splicing in biotechnology. This work was aimed the production of human growth hormone with a native N-terminus in E. coli. A chimeric protein consisting of a short N-terminal peptide, the Mxe GyrA intein, and human growth hormone was constructed. The formyl-methionine modified N-terminal peptide was intended for removal via splicing during translation. This intein has been shown to mediate the cleavage of exteins, but their subsequent ligation has never been observed. This permitted the production of human growth hormone with the native N-terminus. The effect of various factors on cleavage efficiency was also studied. The most efficient cleavage of the chimeric protein (60–80%) was observed in the presence of an inductor (100 mM β-mercaptoethanol) upon incubation for 4–6 days.
Lysosomal Aspartic and Cysteine Proteinases Serum Levels in Patients with Pancreatic Cancer or Pancreatitis (1997)

Lysosomal cathepsins D (CD), B (CB), and L (CL) serum levels were determined by immunoassays in patients with chronic (CHP) or acute (AP) pancreatitis and in patients with ductal pancreatic carcinoma (DPC) and correlated with some biological and clinical parameters of this tumor. CB serum concentrations significantly higher than those measured in healthy subjects (NS) were observed in CHP, AP, and DPC patients (p < 0.01). However, no significant difference was noted among these groups. Increased CL serum levels were evident only in cancer patients compared to NS, AP, or CHP groups (p < 0.05), while no difference was observed among these groups. Elevated CD serum values were observed in CHP and AP patients compared to healthy subjects or cancer patients (p < 0.01). In cancer patients no correlation between CD, CB, and CL and clinical stage or tumor size was found. However, significant correlations were observed only between serum CD and CA50 (p < 0.02) and between CD and CL (p < 0.05). No further relationship among the biochemical parameters examined was observed. The present data suggest that the different serum patterns of CD, CB, and CL in patients with pancreatitis and pancreatic cancer may be of clinical interest as additional biochemical parameters for the differential diagnosis of these diseases. However, further prospective clinical studies are needed to assess better their potential value as prognostic parameters to identify patients with pancreatitis at increased risk to develop pancreatic cancer.
Ahab Wailing in the Wilderness (2003)

Christine Halse's PhD thesis, 'The Reverend Ernest Gribble and Race Relations in Northern Australia' (1992) was published in 2002 as A Terribly Wild Man. Rod Moran wrote two scathing reviews, 'Gribble out of Balance' in the West Australian on June 29, 2002, and with far more detail as 'Ernest Gribble's Dark Torment' in Quadrant, September 2002.
Biosafety Risk Assessment of the Severe Acute Respiratory Syndrome (SARS) Coronavirus and Containment Measures for the Diagnostic and Research Laboratories (2004)

At the end of 2002, an outbreak of a new viral respiratory illness, called SARS (Severe Acute Respiratory Syndrome virus), occurred in China. The disease spread over Asia, North America, Europe, and Africa. In response to the SARS outbreak, the World Health Organization (WHO) coordinated an international collaboration that included clinical, epidemiologic, and laboratory investigations, and initiated efforts to control the spread of SARS. As in other countries, Belgium has been decided to establish biosafety guidelines and recommendations with particular emphasis on handling clinical specimens associated with SARS for research, production, and clinical laboratories. Taking into account that there is so far no SARS case reported in Belgium as well as in other countries in the world, and based on a scientific risk assessment related to the contained use of biological agents, the SARS-CoV was classified as a Risk Group 3 agent. In relation to the reported biosafety assessment, the SARS-CoV should be handled in appropriate biosafety containment levels to avoid laboratory-acquired infections and spread of the disease in the human population and the environment. Therefore, diagnostic activities with inactivated clinical specimens associated with SARS cases and with specimens originating in countries where SARS is documented but not associated with SARS cases should be performed under Biosafety Level 2 (BSL-2) conditions. Diagnostic activities involving non inactivated clinical specimens associated with SARS should be carried out under BSL-2 containment with BSL-3 safety equipment and work practices. Culture of SARS-CoV and all research activities involving SARS-CoV require a BSL-3 containment.
Rapid Prototyping von Videosignalverarbeitungsverfahren / Rapid Prototyping of Video Processing Schemes (2000)

Article Rapid Prototyping von Videosignalverarbeitungsverfahren / Rapid Prototyping of Video Processing Schemes was published on March 1, 2000 in the journal it - Information Technology (volume 42, issue 3).
MP26-10 MAGNETIC RESONANCE IMAGING GUIDED FOCAL LASER THERAPY OF PROSTATE CANCER: FOLLOW UP RESULTS FROM A SINGLE CENTER PHASE I TRIAL (2018)

with both RID (3.3AE1.5 vs 6AE2.6 mm, p0.001) and ELS (4.4AE3.4 vs 9.6AE5.9 mm, p0.001).
Thermomechanical Properties of Polylactic Acid-Graphene Composites: A State-of-the-Art Review for Biomedical Applications (2017)

Due to its biodegradable and bioabsorbable characteristics polylactic acid (PLA) has attracted considerable attention for numerous biomedical applications. Moreover, a number of tissue engineering problems for function restoration of impaired tissues have been addressed by using PLA and its copolymers due to their biocompatibility and distinctive mechanical properties. Recent studies on various stereocomplex formation between enantiomeric PLA, poly(l-lactide) (PLLA) and poly(d-lactide) (PDLA) indicated that stereocomplexation enhances the mechanical properties as well as the thermal- and hydrolysis-resistance of PLA polymers. On the other hand, biomedical application of graphene is a relatively new front with significant potential. Many recent reports have indicated that understanding of graphene-cell (or tissue, organ) interactions; particularly the cellular uptake mechanisms are still challenging. Therefore, use of graphene or graphene oxide properly embedded in suitable PLA matrices can positively impact and accelerate the growth, differentiation, and proliferation of stem cells, conceivably minimizing concerns over cytotoxicity of graphene. As such, PLA-graphene composites hold great promise in tissue engineering, regenerative medicine, and in other biomedical fields. However, since PLA is classified as a hard bio-polyester prone to hydrolysis, understanding and engineering of thermo-mechanical properties of PLA-graphene composites are very crucial for such cutting-edge applications. Hence, this review aims to present an overview of current advances in the preparation and applications of PLA-graphene composites and their properties with focus on various biomedical uses such as scaffolds, drug delivery, cancer therapy, and biological imaging, together with a brief discussion on the challenges and perspectives for future research in this field.
CHAPTER 2. Abundance, Ubiquity and Evolution of Molybdoenzymes (2016)

This chapter summarizes bioinformatics studies of molybdenum-containing enzymes given the dramatic increase in the production of genomic sequences that are now available for a large number of organisms from all three domains of life. These data provide an opportunity to examine occurrence and evolutionary patterns of genes, pathways and biological processes, including molybdenum utilization and molybdoenzymes. Comprehensive analyses have greatly facilitated our understanding of how Mo is used by different organisms and how the distribution and biological functions of molybdoenzymes have been shaped by evolutionary processes. Here, we focus on recent developments involving comparative genomic analyses of Mo utilization and discuss the occurrence and abundance of molybdoenzymes as well as the macroevolutionary trends of molybdenum utilization.
ChemInform Abstract: Condensations of Indeno[2,1‐c]‐1,2‐dithioles Yielding Diindeno[2,1‐b:1′,2′‐e]‐ thiopyran Derivatives. (1986)

Abstract Die Indenodithiole (I) reagieren unter HCl‐Katalyse zu den Diindenothiopyranen (II).
The Role of the Protein Kinase C (PKC) Family in Glucocorticoid-Induced Apoptosis of Human Leukemic Cells. (2005)

Abstract Glucocorticoids (GC’s) are among the most important clinical agents for the treatment of human leukemias. Cells exist, however, that have a functional glucocorticoid (GC) receptor, but are resistance to GC-induced apoptosis—suggesting that major signal transduction pathways (ie PKC family) may influence cellular response to GC. In order to determine whether glucocorticoid-induced apoptosis is mediated by members of the PKC family, we first screened the CEM acute T-cell lymphoblastic leukemic cell line for the presence or absence of all known PKC isoforms. We used two clonal cell lines that were derived from the same parent, CEM-CCRF, but which subsequently developed a pronounced difference in their sensitivity to glucocorticoids. One of these cell lines, CEM C7-14 is sensitive to dexamethasone-induced apoptosis, while the second cell line, CEM C1-15, is resistant. Of the 12 known PKC isoforms, 5 were detected at the basal level, and furthermore that specific members (PKC iota) was up-regulated during resistance, while PKC theta was up-regulated during apoptosis. Selectively inhibiting the entire PKC family caused increased cellular susceptibility to GC-induced apoptosis. Selectively targeting specific isoforms (PKC iota) caused resistant cells to become sensitive to apoptosis. Using immunoflouresence imaging, we showed the selective translocation of PKC’s iota, theta, and alpha after treatment with glucocorticoids. In addition, we showed specific phosphorylation of the isoforms iota, theta, and alpha in cells undergoing DEX-induced apoptosis. Two-dimensional proteomic analysis indicated a large number of proteins in CEM cells that show significant change after DEX treatment. We successfully identified several proteins which were regulated both after treatment with DEX alone, and after treatment with DEX + the PKC specific inhibitor Safingol. These proteins may represent the potential cross talk between the glucocorticoid and PKC apoptosis pathways. Taken together, these studies show that the PKC family is directly involved in glucocorticoid-induced apoptosis.
ChemInform Abstract: FUENFFACH‐KOORDINIERTE HIGH‐SPIN‐EISEN(II)‐KOMPLEXE VON SYNTHETISCHEN MAKROCYCLISCHEN LIGANDEN (1971)

Abstract Die neuen Komplexe (I)‐(III) werden dargestellt.
A hybrid filter for the cancellation of mixed Gaussian noise and impulse noise (2004)

A hybrid filter for mixed noise cancellation is introduced in this paper. The proposed approach combines the advantages of the improved adaptive Wiener filter and bilinear interpolation filter, which can efficiently reduce both the white Gaussian noise and impulse noise. To select the corresponding filters with respect to the noise types, a novel method for impulse noise detection is also designed. Experimental and comparison results show that the proposed approach is particularly effective in removing the mixed Gaussian and impulse noises even with the severe contamination.