gebhart/patrepeval huggingface dataset:
Hybrid Partial Least Squares Models for Batch Processes: Integrating Data with Process Knowledge (2021)

This paper presents a unique strategy for integrating fundamental process knowledge with measurement data to build a partial least squares (PLS) model with improved estimation capability. To this end, variables from two different sources are combined to create the predictor data matrix for the PLS model. Measurement data from sensors is stored and used as inputs to a modified first-principles model to generate trajectory data of unmeasured variables. Then the traditional X data matrix (built with measured data) is augmented with batch trajectory data of the calculated variables. The PLS model built with this augmented matrix is referred to as hybrid/augmented PLS, and this proposed methodology is tested on a seeded batch crystallization process to illustrate this straightforward but powerful approach to estimate the final crystal size distribution. The efficacy of the proposed approach is demonstrated using simulation studies by comparing the results with the standard PLS and subspace based quality model.
ChemInform Abstract: Synthesis of 1‐Substituted 2‐((2S)‐2‐Pyrrolidinyl)pyridine from L‐ Proline. (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
On Communication and Interference Range of Multi-Gbps Millimeter-Wave WPAN System (2010)

This paper investigates the communication range and interference range of millimeter-wave wireless personal area networks (WPAN) based on realistic system design. Firstly, the effective communication range of the millimeter-wave networks are calculated based on realistic physical (PHY) layer design and 60GHz channel obtained from actual measurements. Secondly, an interference model is developed to facilitate the analysis of the impact of interferer-to-victim range on the victim link performance. It is found that system with BPSK modulation is able to support use cases with higher number of portable devices within a 3m range, while system with 16QAM modulation is more suitable for fixed high speed data streaming devices within a shorter range of 1m. Also, the interferer-to-victim range that causes no interference in all conditions is found to be approximately 40m, while a 25m range causes a typical bit error rate (BER) degradation of 1-digit (e.g. BER = 10-6 to 10-5).
Electrochemical Study of a Nano Vesicular Artificial Peroxidase on a Functional Nano Complex Modified Glassy Carbon Electrode (2013)

A nano vesicular was constructed with the complex consisting of hemin, imidazole Gemini and sodium dodecyl sulfate (SDS) in 50 mM phosphate buffer solution (PBS). The novel nano structure acted as an efficient artificial peroxidase (AP). The AP was also immobilized on a carboxyl functionalized multi-walled carbon nano-tubes (MWCNTs-COOH) and gold nano-particles (AuNPs) nano-complex modified glassy carbon (GC) electrode, with a formal potential of -31 ± 2 mV vs. Ag/AgCl in 50 mM PBS, at a scan rate of 0.05 Vs -1. The heterogeneous electron transfer constant (ks) was evaluated to be 5.4 ± 0.1s-1. The modified electrode can be used to detect hydrogen peroxide in the range from 0.03 to 160 μM linearly, with a detection limit of 0.03 μM. The apparent Michaelis-Menten constant (Kmapp) of AP modified electrode was evaluated to be 0.034 ± 0.003mM.
Autosomal dominant distal myopathy: linkage to chromosome 14. (1995)

We have studied a family segregating a form of autosomal dominant distal myopathy (MIM 160500) and containing nine living affected individuals. The myopathy in this family is closest in clinical phenotype to that first described by Gowers in 1902. A search for linkage was conducted using microsatellite, VNTR, and RFLP markers. In total, 92 markers on all 22 autosomes were run. Positive linkage was obtained with 14 of 15 markers tested on chromosome 14, with little indication of linkage elsewhere in the genome. Maximum two-point LOD scores of 2.60 at recombination fraction .00 were obtained for the markers MYH7 and D14S64--the family structure precludes a two-point LOD score > or = 3. Recombinations with D14S72 and D14S49 indicate that this distal myopathy locus, MPD1, should lie between these markers. A multipoint analysis assuming 100% penetrance and using the markers D14S72, D14S50, MYH7, D14S64, D14S54, and D14S49 gave a LOD score of exactly 3 at MYH7. Analysis at a penetrance of 80% gave a LOD score of 2.8 at this marker. This probable localization of a gene for distal myopathy, MPD1, on chromosome 14 should allow other investigators studying distal myopathy families to test this region for linkage in other types of the disease, to confirm linkage or to demonstrate the likely genetic heterogeneity.
Schneidkantenpräparation von VHM-Mikrofräsern*/Cutting edge preparation of cemented carbide micro milling tools – A comparison of different fine machining processes (2015)

Die Prozesssicherheit beim Mikrofräsen lässt sich mit einer gezielten Schneidkantenverrundung erheblich steigern. Dabei werden durch verschiedene Präparationstechnologien unterschiedliche Geometrien und Einflüsse auf den Fräsprozess erzeugt. Der Fachbeitrag behandelt den Einsatz präparierter Mikrowerkzeuge in Zerspanversuchen, in denen auf die Zerspankräfte, den Verschleiß sowie die Oberflächengüten eingegangen wird. &amp;nbsp; Process reliability in micro milling can be increased by a defined cutting edge preparation. Different cutting edge preparations cause different effects on tool behavior in the downstream micro milling process. In this paper, the process forces, the tool wear and the surface quality of prepared micro milling tools are characterized in cutting tests.
MOCVD of coated conductors with electrically conductive buffer layers and their electrical field (2006)

A new MOCVD technique was developed for the deposition of oxides at a controlled low oxygen partial pressure, which enable to coat textured metal tapes with electrical conductive perovskites. In a RTR MOCVD-system metal tapes were coated with electrical conductive (La, Ba)MnO3, (La, Sr)MnO3, (La, Sr, Pb)MnO3 and (La, Ba)2CuO4 buffer layers and YBCO. In the same RTR-system YBCO was deposited on different buffered metal tapes. Computer calculations were used to characterise the behaviour for a weak superconducting part of a CC-tape with a conductive buffer layer system.
Accepting client funds into your account : transparency (2011)

Professional Accountants (SA) are governed the Constitution of the Institute and are bound to act ethically in terms thereof. In terms of clause 7 of the Code of Conduct, members should not be acting on a contingency fee or retainer basis.
Metal–organic framework-derived nickel phosphides as efficient electrocatalysts toward sustainable hydrogen generation from water splitting (2015)

Ni-based metal–organic framework (MOF)-derived Ni<sub>2</sub>P nanoparticles exhibited high-performance for electrochemical HER, as manifested by a low overpotential and a large cathodic current density.
The Roles of Toll-Like Receptors in Atherosclerosis (2009)

Atherosclerosis is a chronic inflammatory disease of the arteries that is characterised by the activation of endothelial cells, the recruitment of monocytes into the vessel wall and the differentiation of recruited macrophages into cholesterol-laden foam cells. Recent evidence from a variety of experimental approaches has indicated that Toll-like receptors (TLRs), which serve to initiate inflammatory signalling in response to the detection of molecules associated with microbial infection or tissue damage, play key roles in the development of atherosclerosis. This review summarises the recent evidence implicating TLR-dependent signalling in the activation of vascular cells during atherogenesis, and the mechanisms by which TLR-signalling may promote the dysregulation of macrophage cholesterol metabolism that is a prerequisite for the formation of foam cells and lesion progressionin vivo. Particular attention is paid to the recent studies aimed at identifying potential ligands of the TLRs that may be relevant to atherogenesis, and the diverse mechanisms by which vascular tissues may become exposed to ligands of the TLRs.
At-Home Use of a Pregnancy-Specific Zone-MPC Closed-Loop System for Pregnancies Complicated by Type 1 Diabetes: A Single-Arm, Observational Multicenter Study (2023)

The results show that the extended use of CLC-P at home until delivery is feasible. Larger, randomized studies are needed to further evaluate system efficacy and pregnancy outcomes.
Influence of fructose and oxygen gradients on fed‐batch recombinant protein production using Bacillus megaterium (2011)

Abstract Bacillus megaterium expressing a variant of the green fluorescent protein (GFP) was used to investigate the influence of gradients in dissolved oxygen (DO) and fructose concentration on biomass and product formation. For this purpose, several fed‐batch experiments with DO as feed control parameter were performed using suboptimal and optimal adjusted control parameters. In a first approach, suboptimal DO‐feeding was reached by varying randomly the controller output between 10 and 20% of the maximal pumping capacity. This led to fluctuations in DO between 20 and 80% and to substrate gradients around 3 g/L. GFP formation thereby was decreased. In a second approach, an optimal feeding profile was realized using a PI‐control with a constant controller output of 20% was used. Thereby no gradients in substrate concentration, but low‐amplitude and high‐frequency oscillations in the DO concentration were obtained, leading to increased GFP formation. In a final experimental approach, large‐scale conditions were emulated in a two‐compartment scale‐down system consisting of a 3.7‐L stirred tank reactor and a 0.7‐L non‐stirred vessel. DO‐based feeding was applied with the measurement in the 3.7‐L bioreactor and feeding in the small vessel. This setup led to a fairly constant gradient of 20% between both vessels, which also resulted in a decreased GFP productivity.
Self-Synchronous and Self-Referenced Coherent Beam Combination for Large Optical Arrays (2007)

A novel and highly accurate electronic technique for phase locking arrays of optical fiber amplifiers is demonstrated. This is the only electronic phase locking technique that does not require a reference beam. The measured phase error for this system is lambda /20. A model for calculating the signal-shot noise-limited phase errors and the phase-modulation-induced phase errors is developed. For the first time, nine fiber amplifiers are coherently combined. The total power in the phase locked array is 100 W.
Molecular Approaches to the Management of Pasture Diseases (1996)

This chapter describes the understanding of resistance to fungal pathogens and possible molecular strategies for improving resistance. Fungal diseases of forage plants include anthracnose, leaf spot, wilts, root, crown and stem rots, seedling damping off, sooty molds, ergot, rusts and mildews. Plant breeding for resistance and disease management are the only workable control strategies. Progress in the development of gene transfer systems for many crop and forage species will enhance the rate of progress in determining whether synthetic resistance is likely to playa significant role in plant protection in the future. Fungal pathogens produce multiple pathogenicity factors to overcome plant defences and to obtain nutrients. The chapter evaluates the concept of using transgenic plants for virus control in pastures, and looks at future developments arising from basic research which promise to overcome presently perceived problems.
A New Sizing Criterion for Conformable and Nonconformable Sand Screens Based on Uniform Pore Structures (2006)

Abstract For decades the sand control industry has utilized Saucier&amp;#8217;s criteria1 to determine gravel sizes with a corresponding screen size for gravel pack operations, while many stand-alone (or non-conformance) screen proponents have utilized other criteria such as Rodgers.2 Other variations of sizing criteria have also been used with some success. Recent advances in the expandable screen market have led to an increasing interest in these screens over gravel packing and non-conformable screens due to the perceived simplicity in screen-sizing criteria and increased productivity. With continually increasing sand control options available to the operator, it is fitting that screen-sizing criteria match the particular application and not be universally employed across all applications. This paper will study the behavioral performance of conformable and non-conformable screens versus gravel packs, relative to plugging resistance and percent of formation solids in the effluent stream. A test matrix was developed using several simulated formation materials from sand prone areas around the world, along with sand control media that was chosen based on the uniformity of its pores. The results indicate that the plugging resistance and percentage of solids in the effluent that passes through the sand control media differs greatly depending on the method of sand control used. The authors outline specific sizing criteria that are necessary for conformable and non-conformable screen applications.
[Initial assessment of the use of polymerase chain reaction (PCR) in diagnosis of tuberculosis among patients of the Center for Diagnosis and Treatment of AIDS]. (1996)

This initial report on the use of PCR in diagnosis of TB was based on a group of 180 patients observed in the AIDS Diagnosis and Therapy Center in Warsaw. Out of 6 patients with positive results of PCR assay for MTB, five had positive AFB smears in induced sputum or BAL, two had positive MTB cultures. Five of them were treated with tuberculostatic drugs with clinical improvement and had negative sputum PCR MTB results after several weeks. Additional 11 patients with AFB positive sputum or BAL smears and negative PCR MTB were observed. None of them developed pulmonary tuberculosis, and none of them was confirmed by culture as MTB infection. The results presented in this paper confirm high specificity and sensitivity of polymerase chain reaction (PCR) as an fast diagnostic test very useful in the clinical settings of AIDS. With the increase of collected material further evaluation will be continued.
Sanitation and disease: health aspects of excreta and wastewater management. (1983)

Public health is of central importance in the design and implementation of excreta disposal projects, and better health is the main social and economic benefit that planners and economists hope to gain by investing in excreta disposal systems. To achieve this gain as much information as possible is needed about the interactions between excreta and health - information not only about broad epidemiological issues of disease prevention through improved excreta disposal, but also about the effect of particular excreta disposal and reuse technologies on the survival and dissemination of particular pathogens. This book sets out to provide such information for a broad readership. It is intended for the wide spectrum of professionals concerned with sanitation and public health. The book has two parts. Part one, entitled "The Health Hazards of Excreta: Theory and Control," presents a distillation of available knowledge about excreta, night soil, and sewage and their effects on health. Part two, entitled "Environmental Biology and Epidemiology of Specific Excreted Pathogens," contains twenty eight chapters, each describing the environmental properties of a specific excreted pathogen or group of excreted pathogens and the epidemiology and control of the infections these pathogens cause.
The Seminal Role of β-Amyloid in the Pathogenesis of Alzheimer Disease (1992)

New molecular information about Alzheimer disease (AD) is appearing at an unprecedented rate. Much interest centers on the beta A4 amyloid protein, which is progressively deposited in senile plaques and blood vessels in AD brain tissue. The discovery that some kindreds with familial AD have a mutation in the gene coding for the beta A4 amyloid precursor protein (APP) suggests that this mutation alone may be sufficient to cause the full spectrum of clinical and pathological changes that characterize AD. Although APP point mutations may turn out to be relatively rare causes of AD, the idea that accelerated beta A4 deposition is an early and critical event in many patients continues to gain support from studies in humans, animals, and cultured cells. Identification of the biochemical steps leading to production of the beta A4 peptide from APP is now a critical issue. Recent reports indicate that normal lysosomal processing pathways can produce carboxyl-terminal fragments of APP that contain the entire beta A4 sequence, and are therefore potentially amyloidogenic. The mechanisms by which such intermediate forms are further processed and released, resulting in extracellular beta A4 deposits in plaques and vessels, are yet to be determined. It is likely that full elucidation of the beta A4-producing pathways will ultimately yield new therapeutic approaches to this complex and tragic disorder.
Carrier Lifetimes in 4H-SiC Epitaxial Layers on the C-Face Enhanced by Carbon Implantation (2018)

Carrier lifetime in low carrier concentration 4H-SiC epitaxial layers grown on the C-face was enhanced by using carbon implantation and post annealing. The measured carrier lifetime increased with the thickness of the epitaxial layer and was 11.4 µs for the 150 µm thick epitaxial layer. The internal carrier lifetime was estimated as 21 µs from the dependence of the measured carrier lifetime on the epitaxial layer thickness. This value is almost comparable to the reported values of the internal carrier lifetime for the layers grown on the Si-face.
Development of an ultra-low temperature multi-frequency ESR apparatus (2009)

An ultra-low temperature multi-frequency electron spin resonance (ESR) apparatus has been developed for use at a temperature down to about 200 mK by utilizing a 3He-4He compact dilution refrigerator and a vector network analyzer. The microwave frequency can be varied between 30 GHz and 700 GHz almost continuously. Either of the two kinds of copper blocks with a sample holder for typical two configurations, namely Faraday and Voigt configurations, is attached to a stainless steel block neighboring to a mixing chamber which provides ultra-low temperarures down to 160 mK. A magnetic field up to 16 T is produced with a superconducting magnet (14 T at 4.2 K and 16 T at 2.2 K). Thus, we have a potential to perform ESR measurements in a very wide frequency-field window at ultra-low temperatures.
Failure Modes in Loaded Carbon/Epoxy Composite T-sections (2007)

The application of composite materials for post-buckling blade-stiffened structures requires capturing the damage which is more critical in the rigid regions of the stiffener-skin interfaces of the panel. In this respect delamination is particularly critical in the interface of the skin and stiffener. In the present experimental investigation, narrow strips consisting of a skin and single stiffener were cut from a large stiffened panel to form T-sections. These sections were loaded until failure in such a way as to produce symmetric and asymmetric displacements, which are typical of the skin-stiffener interfaces in a post-buckling panel. Different failure modes were observed and the first-failure energy was dependent on the failure modes.
Finite‐volume stress analysis in multi‐material linear elastic body (2012)

SUMMARY Correct calculation of stresses at the interface of bonded or otherwise joined materials plays a significant role in many applications. It is therefore important that traction at the material interface is calculated as accurately as possible. This paper describes procedures that can be employed to achieve this goal by using centre‐based finite‐volume method. Total traction at the interface is calculated by decomposing it into normal and tangential components, both being calculated at each side of the interface, and applying the continuity assumption. The way in which the traction approximation is achieved depends on calculation of tangential gradient of displacement at the interface. To this end, three different methods are proposed and validated against problems with known solutions. It was shown that all methods can be successfully used to simulate problems with multi‐material domains, with the procedure based on finite area method being most accurate. Copyright © 2012 John Wiley &amp; Sons, Ltd.
ASP.NET AJAX in Action (2007)

Ajax has revolutionized the way users interact with web pages today. Gone are frustrating page refreshes, lost scroll positions and intermittent interaction with a web site. Instead, we have a new generation of fast, rich, and more intuitive web applications. The ASP.NET AJAX framework puts the power of Ajax into the hands of web developers. ASP.NET AJAX, formerly called Atlas, is a new free framework from Microsoft designed to easily add Ajax features to ASP.NET applications. With this technology, ASP.NET developers can easily build more interactive and highly-personalized web applications that work across all most popular browsers. ASP.NET AJAX in Action is a fast-paced, example-rich tutorial designed for ASP.NET web developers and written by ASP.NET AJAX experts Alessandro Garbin Gallo, David Barkol, and Rama Krishna Vavilala. This book introduces you to Ajax applications and to the ASP.NET AJAX technology. Beginners will appreciate the clear explanations of key ideas and terminology. Intermediate and advanced ASP.NET developers will find a no-nonsense learning source and well-organized reference.ASP.NET AJAX in Action offers a rich set of examples and meticulous explanations. The extensive code samples are accompanied by accurate and rigorous explanations of the concepts behind development with ASP.NET AJAX. In this book, you will discover how to use Microsoft Ajax Library Partial rendering with UpdatePanels Advanced client and server techniques Ajax Control Toolkit If you are a web developer looking to bring your web pages to life and to enhance the user experience, this book is for you.ASP.NET AJAX in Action will give you with the knowledge and tools you need to more easily craft the next generation of Ajax applications. With the help of the Microsoft ASP.NET AJAX framework, Ajax development has never been easier and more instinctive for both client-script developers and ASP.NET developers alike.
Immunological reactions in liver graft perireperfusion in living donor liver transplantation--change of expression of adhesion molecules, deposition of immunoglobulins and cytokine level. (2003)

These results suggested that immunological reactions were generated by the operative procedure in the liver graft to some extent but the graft viability was not severely affected and that antibodies did not play important roles in liver injury in the early period after transplantation, even in anti-donor antibody positive cases.