gebhart/patrepeval huggingface dataset:
Predicting the presence of depressive symptoms in the HIV-HCV co-infected population in Canada using supervised machine learning (2022)

We developed a prediction algorithm that could be instrumental in identifying individuals at risk for depression in the HIV-HCV co-infected population in research settings. Development of such machine learning algorithms using research data with rich predictor information can be useful for retrospective analyses of unanswered questions regarding impact of depressive symptoms on clinical and patient-centred outcomes among vulnerable populations.
Mesh Routing Topologies For FPGA Arrays (1994)

There is currently great interest in using fixed arrays of FPGAs for logic emulators, custom computing devices, and software accelerators. An important part of designing such a system is determining the proper routing topology to use to interconnect the FPGAs. This topology can have a great effect on the area and delay of the resulting system. Tree, Bipartite Graph, and Mesh interconnection schemes have all been proposed for use in FPGA-based systems. In this paper we examine Mesh interconnection schemes, and propose several constructs for more efficient topologies. These reduce inter-chip routing costs by more than 50% over the basic 4-way Mesh. Introduction In the time since they were introduced, FPGAs have moved from being viewed simply as a method of implementing random logic in circuit boards to being a flexible implementation medium for many types of systems. Logic emulation tasks, in which ASIC designs are simulated on large FPGA-based structures [Butts92], have greatly increa...
Structural, Spectroscopic, Electrochemical, and Electroluminescent Properties of Tetraalkoxydinaphthophenazines: New Solution-Processable Nonlinear Azaacenes (2015)

A series of solution-processable tetraalkoxy-substituted dinaphtho[2,3-a:2′,3′-h]phenazines were synthesized by reductive functionalization of indanthrone (6,15-dihydrodinaphtho[2,3-a:2′,3′-h]phenazine-5,9,14,18-tetraone), an old intractable dye. The melting point of these new compounds was found to decrease from 204 °C to 98 °C upon extension of the number of carbons from 4 to 12 in the alkoxy substituent. All derivatives show a strong tendency to self-organize in 2D as evidenced by STM investigations of monolayers deposited on HOPG. The 2D structure is less dense and shows different alkoxy group interdigitation pattern as compared to the 3D structure determined from the X-ray diffraction data obtained for the corresponding single crystals. Electrochemical, absorption, and emission properties of tetraalkoxy-substituted dinaphtho[2,3-a:2′,3′-h]phenazines, studied in solution, are essentially independent of the length of the alkoxy substituents. All derivatives exhibit high photoluminescence quantum yield, approaching 60%. When molecularly dispersed in a solid matrix consisting of poly(9-vinylcarbazole) (PVK) (60 wt %) and (2-tert-butylphenyl-5-biphenyl-1,3,4-oxadiazole) (PBD) (40 wt %) (so-called “guest/host configuration”), they show green electroluminescence due to an effective energy transfer from the matrix to the luminophore. The best light-emitting diodes were obtained for the butoxy derivative showing a luminance approaching 1500 cd/m2 and a luminous efficiency over 0.8 cd/A.
A 60GHz CMOS phased-array transceiver pair for multi-Gb/s wireless communications (2011)

Recent advances in silicon technology, mm-Wave integrated circuit/antenna/package design, and beam-forming techniques at 60GHz, together with the emergence of suitable wireless standards, have enabled consumer electronics products to support wireless transmission of multi-Gb/s data such as high-definition (HD) audio/video content. Further expansion into portable and mobile platforms will require lower power consumption, smaller form factor, and lower cost. This paper describes a fully integrated, low-cost 60GHz phased-array transceiver pair, implemented in 65nm standard digital CMOS and packaged with an embedded antenna array, capable of robust 10m non-line of sight (NLOS) communication. The array is configurable from 32 elements to 8 or fewer elements, making the transceiver pair suitable for both fixed, high-data-rate and portable, low-power applications. To enhance the robustness of the multi-element design, dynamic phase shifters allow the beam direction to be changed in real time to adapt to changing environments without interruption of the multi-Gb/s data stream. The transceiver pair supports the WirelessHD and draft 802.11ad (WiGig) standards at maximum data rates of 7.14Gb/s and 6.76Gb/s, respectively.
Radiocolloids in sorption systems. XV. Influence of the pseudocolloidal state of a sorbate on the sorption kinetics (1986)

This paper examines the influence of the pseudocolloidal aggregative forms of a sorbate on the sorption kinetics. It is established that the deviation of the 1n (1-F) versus t kinetic curve from linearity, as well as the acceleration of sorption after an interruption of the process, may not be only signs of a mixed-diffusion mechanism for the sorption process, but also a consistent consequence of the presence of pseudocolloids in the solution. Hindrance of the conversion of the unsorbed ionic forms of the sorbate into sorbed forms, as well as the competitive action of the surface of the vessel, may have similar influence on the sorption kinetics.
Use of Intranasal Fentanyl in Children Undergoing Myringotomy and Tube Placement during Halothane and Sevoflurane Anesthesia (2000)

Serum fentanyl concentrations after intranasal administration exceed the minimum effective steady state concentration for analgesia in adults. The use of intranasal fentanyl during halothane or sevoflurane anesthesia for BMT is associated with diminished postoperative agitation without an increase in vomiting, hypoxemia, or discharge times.
Molecular dissection of a contiguous gene syndrome: localization of the genes involved in the Langer--Giedion syndrome (1995)

The Langer-Giedion syndrome (tricho-rhino-phalangeal syndrome type II, TRPS II) is characterized by craniofacial dysmorphism and skeletal abnormalities. It combines the clinical features of TRPS I and multiple cartilaginous exostoses (EXT). We have used YAC cloning, Southern blotting, PCR analysis, and fluorescence in situ hybridization to study chromosome 8 deletions, translocations, an inversion, and an insertion in patients with TRPS I, TRPS II or EXT. Our results indicate that the TRPS gene maps more than 1,000 kb proximal to the EXT1 gene and that both genes are affected in TRPS II. We conclude that TRPS II is not due to pleiotropic effects of mutations in a single gene, but that it is a true contiguous gene syndrome.
Temperature dependence of diffusion of a disperse dye in the multiple layers of nylon fabric (1991)

Abstract The apparent diffusion coefficients of a disperse dye in the multiple layers of nylon fabric at 45‐75°C are determined as the dyeing model of the textile assembly. The modified pore model is introduced to explain the diffusion behavior in the multiple fabric. The Arrhenius plot of the diffusion coefficient of dye in the spaces or pores of nylon fabric gave a straight line and the activation energy of diffusion was about 9.4 kcal/mol. The temperature dependence of the dye diffusivity in polymer matrix was quantitatively described by a WLF‐type relation, where a T is a shift factor of diffusion and T s is the reference temperature.
Genomic Minimalism in the Early Diverging Intestinal Parasite Giardia lamblia (2007)

The genome of the eukaryotic protist Giardia lamblia, an important human intestinal parasite, is compact in structure and content, contains few introns or mitochondrial relics, and has simplified machinery for DNA replication, transcription, RNA processing, and most metabolic pathways. Protein kinases comprise the single largest protein class and reflect Giardia's requirement for a complex signal transduction network for coordinating differentiation. Lateral gene transfer from bacterial and archaeal donors has shaped Giardia's genome, and previously unknown gene families, for example, cysteine-rich structural proteins, have been discovered. Unexpectedly, the genome shows little evidence of heterozygosity, supporting recent speculations that this organism is sexual. This genome sequence will not only be valuable for investigating the evolution of eukaryotes, but will also be applied to the search for new therapeutics for this parasite.
The Haptoglobin β chain as a supportive biomarker for human lung cancers (2011)

Haptoglobin (Hp) is produced as an acute phase reactant during inflammation, infection, malignant diseases, and several cancers. In proteomics analysis using human blood samples, the Hp peptide levels were about 3-fold higher in lung cancer patients versus normal individuals. This study is aimed at analyzing the elevation of which chain of Hp is closely related to lung cancers and can be a serum biomarker for lung cancers. In Western blot (WB) analysis, we found that the Hp β chain can be a better diagnostic biomarker for lung cancers. In the result of the Hp β chain ELISA developed by us, the concentrations of the Hp β chain in the sera increased about 4-fold in 190 lung adenocarcinoma patients versus 190 healthy controls (8.0 ± 3.8 μg ml(-1)vs. 1.9 ± 1.2 μg ml(-1)). ELISA data showed that the serum levels of the Hp β chain in breast cancer (1.5 ± 0.5 μg ml(-1)) and hepatocellular carcinoma (HCC) (1.4 ± 1.0 μg ml(-1)) patients remained similar to those of healthy controls. Compared to lung adenocarcinoma, the Hp β chain levels in the plasma of patients with other respiratory diseases such as tuberculosis (TBC), idiopathic pulmonary fibrosis (IPF) and bronchial asthma (BA) were closer to those of healthy controls. Our data suggest that an increase of the Hp β chain can be a potential serum biomarker for lung cancers.
Quality relevant fault detection of batch process via statistical pattern and regression coefficient (2020)

Abstract Compared with the normal process, the statistical values or the relationships between process variables and the quality that represent process situations would change in an abnormal batch. A novel method named quality relevant fault detection based on statistical pattern and regression coefficients (SPRC) is proposed for the batch process. Firstly, the statistical patterns of the process data, such as mean value and SD, are computed to quantify process characteristics. The regression model is built via linear methods, such as multiple linear regression, least absolute shrinkage and selection operator, to describe the linear relationship. The mutual information between the quality and the process parameters is used to characterize the nonlinear relationship. In this way, statistical patterns and regression coefficients which express batch information constitute the two‐way matrix. Then, the matrix is dimensionally reduced by related method, such as principal component analysis. The relationships hidden in batch process could be sought by SPRC. Finally, two cases, penicillin fermentation and steel hot rolling, are used to validate the feasibility and advantages of the proposed method.
Catalytic Hydrogenation of Vegetable Oils (2014)

Partial and full hydrogenation of vegetable oils are extremely important for the food and chemical industries. The selectivity of the catalytic process determines the chemical and physical properties of the hydrogenated products, defining the application potential, and therefore the product value. In the partial hydrogenation, the conversion of unstable polyunsaturated fatty acids into more stable monounsaturated fatty acids is highly desired, without a significant increase in the content of saturated fatty acids. Nowadays, the challenge is the control of the cis/trans isomerization, occurring as a side reaction of the hydrogenation process, since trans fatty acids are suspected of increasing the risk of cardiovascular diseases. Accordingly, in many countries, there are specific regulations banning the use of trans fats in food products. Since catalyst properties largely influence hydrogenation selectivity and formation of trans isomers, catalyst development is crucial in providing products showing superior functionality, i.e. good stability, suitable physical properties, and low levels of trans isomers.
ChemInform Abstract: N,N′‐Bisacylimidazolidines from 1,2‐Diamines. (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A cost-minimization analysis in minimally invasive spine surgery using a national cost scale method (2015)

This medico-economic study has leaded to choose preferentially the use of minimally invasive surgery techniques. This study also illustrates the discrepancy between the national health system reimbursement and real hospital charges. The medico-economic is becoming critical in the current context of sustainable health resource allocation.
Speech fundamental frequency estimation by multi-channel peak-picking (1987)

A variety of methods have been implemented for speech fundamental frequency (Fx) estimation from an acoustic input, but none can reliably estimate Fx in typical acoustic environments. The purpose of this paper is to describe developments, based an current theories of human pitch perception, to the design of a device which is used in speech processing hearing aids, speech training aids and speech research.
Cloning-free CRISPR/Cas system facilitates functional cassette knock-in in mice (2015)

Although the CRISPR/Cas system has enabled one-step generation of knockout mice, low success rates of cassette knock-in limit its application range. Here we show that cloning-free, direct nuclear delivery of Cas9 protein complex with chemically synthesized dual RNAs enables highly efficient target digestion, leading to generation of knock-in mice carrying a functional cassette with up to 50% efficiency, compared with just 10% by a commonly used method consisting of Cas9 mRNA and single guide RNA. Our cloning-free CRISPR/Cas system facilitates rapid one-step generation of cassette knock-in mice, accelerating functional genomic research by providing various in vivo genetic tools.
A nuclear protein binding to dA/dT-rich sequences upstream from the radish DMA promoter (1992)

Summary
The external spacer (ES) of rRNA nuclear genes (rDNA) contains the sequences that control rDNA transcription initiation and enhancement. The ES is also characterized in most species by the presence of multiple repeated elements. In higher plants very few data are available on the cis- and fransacting elements which control rDNA transcription. Using electrophoretic mobility shift assays (EMSA) it is shown that nuclear extracts from young radish leaves (NER) contain a protein fraction which binds to specific sequences in the radish ES. DNase I footprinting analysis allows mapping of the NER protein binding to dA/dT homo-polymer stretches and to a 13-bp dA/dT-rich short repeat, found both in the seven approximately 100 bp repeat regions (located -1077 to-740 from transcription initiation site) and the region (-120 to -55) containing the putative promoter for rDNA transcription initiation. Whether this ES binding is due to a single or several different proteins is not known. So far, protein(s) binding to dA/dT-rich regions of a plant rDNA ES has not yet been described. Whether it is a specific RNA polymerase I transcription factor(s) or plays a more general role in genome expression remains to be elucidated.
Biomarkers of Infection and Risk of Coronary Heart Disease (2006)

Chronic infection has been found to be significantly associated with the development of atherosclerosis and the clinical complications of unstable angina, myocardial infarction, and stroke. A variety of infectious agents have been proposed to be involved in atherothrombosis, and, indeed, the number of implicated agents continues to increase each year. These include specific bacterial and viral agents, as well as a variety of agents associated with periodontal disease. However, failure to confirm initial reports of serological associations also has been common. The infectious agents with the most evidence to support an etiological role in atherosclerosis include Chlamydia pneumoniae and cytomegalovirus. In addition, evidence is mounting for a variety of other potential agents including other herpes viruses, influenza, other specific bacteria (such as Mycoplasma pneumoniae), and chronic infections with common bacterial agents (e.g., periodontal disease, chronic bronchitis, chronic urinary tract infection). Nevertheless, specific causative relationships on par with that determined between Helicobacter pylori and peptic ulcer disease have not yet been established. In addition, treatment of some of these pathogens has failed to reduce the risk of cardiovascular complications. Future studies are expected to elucidate further the pathophysiological relationship between chronic infection and atherosclerosis and the potential of a variety of treatment approaches including antibiotics. Until then, however, a general recommendation for the use of any of these infectious markers during routine cardiovascular risk stratification cannot be made.
Bidirectional Protocol Independent Multicast (BIDIR-PIM) (2007)

This document discusses Bi-directional PIM, a variant of PIM Sparse-
Mode [4] that builds bi-directional shared trees connecting multicast
sources and receivers. Bi-directional trees are built using a fail-
safe Designated Forwarder (DF) election mechanism operating on each
link of a multicast topology. With the assistance of the DF, multicast
data is natively forwarded from sources to the Rendezvous-Point and
hence along the shared tree to receivers without requiring source-
specific state. The DF election takes place at RP discovery time and
provides the route to the RP thus eliminating the requirement for
data-driven protocol events.
Data from MAP4K3/GLK Promotes Lung Cancer Metastasis by Phosphorylating and Activating IQGAP1 (2023)

&lt;div&gt;Abstract&lt;p&gt;Overexpression of the serine/threonine kinase GLK/MAP4K3 in human lung cancer is associated with poor prognosis and recurrence, however, the role of GLK in cancer recurrence remains unclear. Here, we report that transgenic GLK promotes tumor metastasis and cell migration through the scaffold protein IQ motif–containing GTPase-activating protein 1(IQGAP1). GLK transgenic mice displayed enhanced distant metastasis. IQGAP1 was identified as a GLK-interacting protein; two proline-rich regions of GLK and the WW domain of IQGAP1 mediated this interaction. GLK and IQGAP1 colocalized at the leading edge including filopodia and lamellipodia of migrating cells. GLK directly phosphorylated IQGAP1 at Ser-480 enhancing Cdc42 activation and subsequent cell migration. GLK-induced cell migration and lung cancer metastasis were abolished by IQGAP1 depletion. Consistently, human NSCLC patient tissues displayed increased phospho-IQGAP1, which correlated with poor survival. Collectively, GLK promotes lung cancer metastasis by binding to, phosphorylating, and activating IQGAP1.&lt;/p&gt;Significance:&lt;p&gt;These findings show the critical role of the GLK–IQGAP cascade in cell migration and tumor metastasis, suggesting it as a potential biomarker and therapeutic target for lung cancer recurrence.&lt;/p&gt;&lt;/div&gt;
Roof tile frangibility and puncture of metal window shutters (2013)

The goal of this study was to investigate the vulnerability of roof tile systems and metal shutters to roof tile debris. Three phases addressed the performance of tile roof systems and metal shutters impacted by roof tile debris. The first phase experimentally evaluated the tile fragment size and quantity generated by a tile striking a tile roof system. The second phase experimentally quantified the puncture vulnerability of common metal panel shutter systems as a function of tile fragment impact speed. The third phase provided context for interpretation of the experimental results through the use of a tile trajectory model. The results provide supporting evidence that while metal panel window shutters provide significant protection against a prevalent form of windborne debris, these systems are vulnerable to tile fragment puncture in design level tropical cyclones. These findings correlate with field observations made after Hurricane Charley (2004).
The Spreading of Air Peaks in Capillary and Packed Gas Chromatographic Columns. (1963)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Spreading of Air Peaks in Capillary and Packed Gas Chromatographic Columns.J. H. Knox and Lilian. McLarenCite this: Anal. Chem. 1963, 35, 4, 449–454Publication Date (Print):April 1, 1963Publication History Published online1 May 2002Published inissue 1 April 1963https://pubs.acs.org/doi/10.1021/ac60197a033https://doi.org/10.1021/ac60197a033research-articleACS PublicationsRequest reuse permissionsArticle Views84Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Beach Nourishment in Presence of Seawall (1994)

Beach nourishment, placed along a seawalled shoreline, can exhibit a markedly different behavior than projects on shorelines with adequate compatible sands to transport. The most striking effects of engineering significance are: (1) The migration of the centroid of the nourishment planform anomaly when acted on by oblique waves; and (2) a potentially different (currently unknown) rate of spreading of the planform anomaly. Under the most idealized considerations of uniform transport along the nourished shoreline, the speed of centroid migration is shown to increase as the planform anomaly spreads out under the mobilizing action of the waves, and the rate at which the planform spreading (dispersion) occurs is not affected by the seawall. Also, for normally incident waves, the seawall does not affect the planform evolution. Analytical, numerical, and experimental approaches are employed to demonstrate the aforementioned effects. It is shown that the transport at the ends of the project, where all the nourishment sand is submerged, can affect results substantially. These effects of the presence of a seawall on beach‐nourishment project performance appear to have not been reported previously.
Electrical and Optical Characterization of Ultrathin Tellurium Nanostructures Synthesized by Vapor Phase Deposition (2019)

Abstract not provided.
Plant defense peptides (1998)

Eight families of antimicrobial peptides, ranging in size from 2 to 9 kD, have been identified in plants. These are thionins, defensins, so-called lipid transfer proteins, hevein- and knottin-like peptides, MBP1, IbAMP, and the recently reported snakins. All of them have compact structures that are stabilized by 2-6 disulfide bridges. They are part of both permanent and inducible defense barriers. Transgenic overexpression of the corresponding genes leads to enhanced tolerance to pathogens, and peptide-sensitive pathogen mutants have reduced virulence.