gebhart/patrepeval huggingface dataset:
Quantitative evaluation of induction motor broken bars by means of electrical signature analysis (2001)

The paper reports the comparison and performance evaluation of different diagnostic procedures that use input electric signals to detect and quantify rotor breakage in induction machines supplied by the mains. Besides the traditional current signature analysis based on one-phase current spectrum lines at frequencies (1/spl plusmn/2s)f, the procedures based on analysis of the line at frequency 2sf in the spectrum respectively of electromagnetic torque, space vector current modulus and instantaneous power are considered. These last procedures have similar features and the comparison is developed on the basis of instantaneous torque. It is addressed that the speed ripple introduces two further terms in the instantaneous torque, decreasing the accuracy of the diagnosis. It is shown that there is a link between the angular displacement of the current sideband components at frequencies (1/spl plusmn/2s)f. This allows a more correct quantitative evaluation of the fault and shows the superiority of the side band current components diagnostic procedure over the other proposed methods.
Intriguing Indium-salen Complexes as Multicolor Luminophores (2017)

The series of novel salen-based indium complexes (3-<sup>t</sup>Bu-5-R-salen)In-Me (3-<sup>t</sup>Bu-5-R-salen = N,N'-bis(2-oxy-3-tert-butyl-5-R-salicylidene)-1,2-diaminoethane, R = H (1), <sup>t</sup>Bu (2), Br (3), Ph (4), OMe (5), NMe<sub>2</sub> (6)) and [(3-<sup>t</sup>Bu-5-NMe<sub>3</sub>-salen)In-Me](OTf)<sub>2</sub> (7; OTf = CF<sub>3</sub>SO<sub>3</sub><sup>-</sup>) have been synthesized and fully characterized by NMR spectroscopy and elemental analysis. All indium complexes 1-7 are highly stable in air and even aqueous solutions. The solid-state structures for 3-5, which were confirmed by single-crystal X-ray analysis, exhibit square-pyramidal geometries around the indium center. Both the UV/vis absorption and PL spectra of 1-7 exhibit significant intramolecular charge transfer (ICT) transitions based on the salen moieties with systematically bathochromic shifts, which depend on the introduction of various kinds of substituents. Consequently, the emission spectra of these complexes cover almost the entire visible region (λ<sub>em</sub> = 455-622 nm).
Presynaptic Mechanism for Anti-Analgesic and Anti-Hyperalgesic Actions of κ-Opioid Receptors (2003)

Glutamate neurotransmission plays an important role in the processing of pain and in chronic opioid-induced neural and behavioral plasticity, such as opioid withdrawal and opioid dependence. Kappa-opioid receptors also have been implicated in acute opioid modulation of pain and chronic opioid-induced plasticity, both of which are primarily mediated by mu-opioid receptors. Using whole-cell patch clamp recordings in brain slices in vitro and system analysis of pain behaviors in rats in vivo, this study investigated the functional role of glutamate synaptic transmission and kappa-opioid receptors in two behavioral pain conditions: m-opioid-induced analgesia (decreased pain) and mu-opioid withdrawal-induced hyperalgesia (increased pain). In the nucleus raphe magnus (NRM), a brainstem structure that controls spinal pain transmission, we found that kappa-receptor agonists presynaptically inhibited glutamate synaptic currents in both of the two cell types that are thought to respectively inhibit or facilitate spinal pain transmission. In rats, both glutamate receptor antagonists and the kappa agonist microinjected into the NRM attenuated mu-opioid-induced analgesia, which is most likely mediated through activation of such pain-inhibiting neurons. However, during opioid abstinence-induced withdrawal, the same doses of glutamate receptor antagonists and the kappa agonist administered in the NRM suppressed the withdrawal-induced hyperalgesia, which is thought to be mediated by activation of those pain-facilitating neurons during opioid withdrawal. These results demonstrate that kappa-opioid receptors antagonize mu-receptor-induced effects in both analgesic and hyperalgesic states, and suggest inhibition of glutamate synaptic transmission as a presynaptic mechanism for the kappa antagonism of these two mu receptor-mediated actions.
Progress in Laser-Driven Ion Acceleration towards Applications in Radiotherapy (2014)

We will outline recent progress, in the UK ASAIL laser-ion acceleration programme, which aims to advance laser-driven ion beams to the point at which they will become a serious alternative to conventional accelerators for radiotherapy.
Identification of fenestrated capillary segments in microvascular corrosion casts of the rat exocrine pancreas (1994)

Abstract The capillary bed of the rat exocrine pancreas was studied by scanning and transmission electron microscopy of corrosion casts and tissue sections. Two types of capillaries were distinguished in corrosion casts. First, there were straight capillaries of relatively constant width (mean diameter 4.79±0.87 μm), which were characterized by numerous circular constrictions on their surface. About 37% of the capillaries belonged to this type. Second, there were undulating capillaries which showed smooth surfaced eccentric dilatations defined by similar surface constrictions. The bulging areas measured 8.43 ± 1.33 μm, the constrictions next to the bulges figured for 6.45 ± 1.53 μm. About 63% of the capillaries belonged to the second type. Two types of capillaries were also identified in tissue sections. First, there were capillaries with continuous endothelial lining (26% of capillary profiles; mean diameter 5.48 ± 1.67 μm); 27% of their endothelial lining was provided with underlying pericytes. Second, there were capillaries with fenestrated endothelium (64% of capillary profiles; mean diameter 6.16 ± 1.75 μm); 12% of their endothelial lining was accompanied by pericytes. According to frequency and dimension of these two types of capillaries, we conclude that bulged and undulating capillary casts correspond to fenestrated capillaries and straight capillary casts of constant width correspond to nonfenestrated capillaries. The frequency of crests on the surface of capillary casts correlates with the different frequency of pericyte processes on fenestrated and nonfenestrated capillaries. It is concluded that pericyte processes beneath the endothelium hold resistance against luminal pressure. Bulging areas of capillary casts correlate with fenestrated areas of endothelial lining, that is, areas which are not reinforced by pericyte processes.
Spiral and square microstructured surfaces: The effect of the decreasing size of photo‐immobilized hyaluronan domains on cell growth (2009)

Spiral and squared micropatterned surfaces of decreasing dimensions were realized by photo-immobilizing a photoreactive hyaluronan (Hyal) derivative on silanized glass substrates. The microstructured surfaces were observed by atomic force microscope and scanning electron microscope. Scanning electron microscope analysis revealed the presence of a spiral (ranging from 100 microm down to 1 microm in the central part) and a square pattern consisting of a central square of 100 microm x 100 microm and squares of different dimensions decreasing from the centre to the edges of the micropatterned area (2 microm x 1 microm). Three cell types were tested on all the microstructured surfaces: human coronary artery endothelial cells (HCAEC), human dermal fibroblasts (C54), and NIH 3T3 fibroblasts. Cell adhesion analysis demonstrated that HCAEC and C54 did not adhere to the immobilized Hyal on silanized glass but adapted their shape to the different sizes of the square and spiral patterns. Also, in both geometric patterns, the reduction of the adhesive glass width induced C54 to create bonds amongst themselves. NIH 3T3 cells adhered inside the squares and the spiral but reducing the adhesive glass width induced NIH 3T3 to adhere to immobilized Hyal. This fact is explained by the interactions between the cells and the immobilized Hyal as a consequence of the CD44/Hyal binding.
Techniques for improving in-building radio coverage using fiber-fed distributed antenna networks (2002)

The characteristics of an in-building fiber-fed distributed antenna network are addressed by simulation of an indoor non-shadowed radio environment at 900 MHz, 1.8 and 1.9 GHz. The performance of the network is discussed in terms of the number and placement of antennas, and the method of diversity combination used. Statistical analysis of the radio environment shows that the arbitrary placement of two fiber-fed antennas in the room is as good as conventional half-wave diversity. Furthermore, the performance of multiple distributed antennas (>3) is typically superior to non-distributed architectures.
Single‐agent lenalidomide maintenance after upfront autologous stem cell transplant for newly diagnosed multiple myeloma: The MD Anderson experience (2023)

The optimal duration of lenalidomide (Len) maintenance for patients with multiple myeloma (MM) after autologous stem cell transplantation (autoHCT) is unknown. We conducted a retrospective single-center analysis of adult MM patients that received upfront autoHCT between 2005 and 2021, followed by single-agent Len maintenance. A total of 1167 patients were included with a median age of 61.4 (range 25.4-82.3) years, and high-risk chromosomal abnormalities in 19%. Median duration of maintenance was 22.3 (range 0.03-139.6) months. After a median follow-up of 47.9 (range 2.9-171.7) months, median PFS and OS for the entire cohort were 56.6 (95% CI 48.2-61.4) months and 111.3 (95% CI 101.7-121.5) months, respectively. In MVA, high-risk cytogenetics was associated with a worse PFS (HR 1.91) and OS (HR 1.73) (p < .001 for both). Use of KRD induction and achievement of MRD-negative ≥ VGPR before autoHCT were associated with an improved PFS (HR 0.53 and HR 0.57, respectively; p < .001 for both). Longer maintenance duration, even with a 5-year cutoff, was associated with superior PFS and OS (HR 0.17 and 0.12, respectively; p < .001 for both). A total of 106 patients (9%) developed a second primary malignancy (SPM), mostly solid tumors (39%) and myeloid malignancies (30%). Longer maintenance duration was associated with a higher risk of SPM, reaching statistical significance after >2 years (odds ratio 2.25; p < .001). In conclusion, outcomes with Len maintenance were comparable to those reported in large clinical trials. Longer duration of maintenance, even beyond 5 years, was associated with improved survival.
Highlight removal based on the regional-projection fringe projection method (2018)

In fringe projection profilometry, highlight usually causes the saturation and blooming in captured fringes and reduces the measurement accuracy. To solve the problem, a regional-projection fringe projection (RP-FP) method is proposed. Regional projection patterns (RP patterns) are projected onto the tested object surface to avoid the saturation and blooming. Then, an image inpainting technique is employed to reconstruct the missing phases in the captured RP patterns and a complete surface of the tested object is obtained. Experiments verified the effectiveness of the proposed method. The method can be widely used in industrial inspections and quality controlling in mechanical and manufacturing industries.
Computational Modeling of Seizure Dynamics Using Coupled Neuronal Networks: Factors Shaping Epileptiform Activity (2015)

Epileptic seizure dynamics span multiple scales in space and time. Understanding seizure mechanisms requires identifying the relations between seizure components within and across these scales, together with the analysis of their dynamical repertoire. Mathematical models have been developed to reproduce seizure dynamics across scales ranging from the single neuron to the neural population. In this study, we develop a network model of spiking neurons and systematically investigate the conditions, under which the network displays the emergent dynamic behaviors known from the Epileptor, which is a well-investigated abstract model of epileptic neural activity. This approach allows us to study the biophysical parameters and variables leading to epileptiform discharges at cellular and network levels. Our network model is composed of two neuronal populations, characterized by fast excitatory bursting neurons and regular spiking inhibitory neurons, embedded in a common extracellular environment represented by a slow variable. By systematically analyzing the parameter landscape offered by the simulation framework, we reproduce typical sequences of neural activity observed during status epilepticus. We find that exogenous fluctuations from extracellular environment and electro-tonic couplings play a major role in the progression of the seizure, which supports previous studies and further validates our model. We also investigate the influence of chemical synaptic coupling in the generation of spontaneous seizure-like events. Our results argue towards a temporal shift of typical spike waves with fast discharges as synaptic strengths are varied. We demonstrate that spike waves, including interictal spikes, are generated primarily by inhibitory neurons, whereas fast discharges during the wave part are due to excitatory neurons. Simulated traces are compared with in vivo experimental data from rodents at different stages of the disorder. We draw the conclusion that slow variations of global excitability, due to exogenous fluctuations from extracellular environment, and gap junction communication push the system into paroxysmal regimes. We discuss potential mechanisms underlying such machinery and the relevance of our approach, supporting previous detailed modeling studies and reflecting on the limitations of our methodology.
Antegrade internal ureteral stenting: a technical refinement. (1985)

A pliable, easy to place, double pigtail, internal ureteral stent made of elastomeric polyurethane is described. The tapered distal pigtail end minimizes bladder irritation and the combination of a pusher and absorbable suture enables optimal placement of the proximal pigtail end in the renal pelvis. Ten stents used in eight patients remained functional without bladder irritation for a mean period of 8 months (range, 2-14 months).
Proyección social de la Universidad (1999)

L'enseignement et la recherche sont traditionnellement les deux fonctions de l'universite, fonctions qui n'ont jamais eu de repercussions sociales aussi fortes qu'a notre epoque, notamment lorsque les activites universitaires sont consacrees a la formation professionnelle, au developpement socio-culturel et a la recherche appliquee. Ces fonctions d'enseignement et de recherche acquierent de plus une dimension particuliere dans le contexte de communication et de collaboration culturelles actuel (liens avec les pays en developpement, avec les programmes europeens et internationaux); la didactique a l'universite s'en trouve modifiee au niveau de la programmation, des methodes et des evaluations.
A Personalized Physical Activity Coaching App for Breast Cancer Survivors: Design Process and Early Prototype Testing (2020)

Implementing a user-centered design approach for the development and early evaluation of an app brings essential considerations to tailor the solution to the user's needs and context. In addition, informing the design on behavioral and tailored coaching theories supports the conceptualization of the PA coaching system. This is critical for optimizing the usability, acceptability, and long-term effectiveness of the tool. After successful early in-laboratory testing, the app will be developed and evaluated in a pilot study in a real-world setting.
Las adicciones, hallazgos genómicos (2012)

"Una frase empleada en el argot científico en los primeros años de la era de la genética dictaba que "X es un gen para Y", en donde X representaba a un gen particular del genoma humano y Y correspondía a uno de los complejos trastornos de la conducta humana como la depresión, la agresión, la orientación sexual, la obesidad, la infidelidad, la esquizofrenia y la adicción. Sin embargo, ahora se sabe que la contribución genética a los trastornos psiquiátricos se debe a la acción conjunta de grupos de genes que de manera individual causarían sólo un pequeño impacto incapaz de desencadenar alteraciones conductuales. La contribución de los grupos de genes aunada a un sinnúmero de factores ambientales y sociales es la causa de la amplia variedad de perturbaciones conductuales en el humano. De esta manera, la frase "X es un gen para Y", es inapropiado para los cuadros psiquiátricos. La conducta patológica más importante en la adicción es labúsqueda compulsiva de la droga y la pérdida del control en el deseode obtenerla. Otra de las graves consecuencias de la adicción es elriesgo de recaídas de los individuos a pesar de tener varios años deabstinencia. Esta última característica ha sido el punto de elecciónpara implementar medidas terapéuticas más eficientes. Para lograrque las terapias sean exitosas es necesario entender los mecanismosneurobiológicos que intervienen en los procesos de adquisición yconsolidación del síndrome adictivo. Uno de los puntos que ha llamadola atención es el hecho de que el riesgo de las recaídas puedepersistir durante varios años y ha permitido implicar la generaciónde cambios en la fisiología del cerebro que se mantienen por largosperiodos. Así, es de suma relevancia comprender las bases neurobiológicasde los procesos adictivos que ocasionan cambios en laplasticidad neural.La finalidad de esta revisión es analizar algunos ejemplos representativosde los recientes avances en el campo de las ciencias genómicasque permiten ampliar el conocimiento de las implicaciones anivel celular de los procesos adictivos y la importancia que tendrándichos avances para mejorar la práctica psiquiátrica en general y, demanera específica, el tratamiento de las conductas adictivas.Se describen algunos de los trabajos recientes en los que se haestudiado la modificación de la expresión génica como consecuenciade la administración de drogas de abuso en diferentes paradigmasde estudio, incluyendo estudios en los que se evalúa la similitud delos efectos ocasionado por tres drogas de abuso diferentes: cocaína,marihuana y fenilciclina.Finalmente se describen las implicaciones moleculares de lasmodificaciones en la expresión génica de proteínas que participan endiferentes procesos celulares, como el metabolismo del colesterol y loslípidos, las funciones del aparato de Golgi y el retículo endoplásmico,el tráfico intracelular en el citoesqueleto.Todos estos cambios representan modificaciones importantes enla función sináptica y"
Biocatalytic coatings for air pollution control: A proof of concept study on VOC biodegradation (2014)

Although biofilm-based biotechnologies exhibit a large potential as solutions for off-gas treatment, the high water content of biofilms often causes pollutant mass transfer limitations, which ultimately limit their widespread application. The present study reports on the proof of concept of the applicability of bioactive latex coatings for air pollution control. Toluene vapors served as a model volatile organic compound (VOC). The results showed that Pseudomonas putida F1 cells could be successfully entrapped in nanoporous latex coatings while preserving their toluene degradation activity. Bioactive latex coatings exhibited toluene specific biodegradation rates 10 times higher than agarose-based biofilms, because the thin coatings were less subject to diffusional mass transfer limitations. Drying and pollutant starvation were identified as key factors inducing a gradual deterioration of the biodegradation capacity in these innovative coatings. This study constitutes the first application of bioactive latex coatings for VOC abatement. These coatings could become promising means for air pollution control.
Film bulk acoustic wave resonator technology (2002)

It is demonstrated that completely monolithic two-pole filters can be fabricated on silicon substrates using FBARs (film bulk acoustic resonators) and that these filters have low loss and reasonable bandwidth. A two-pole monolithic ladder filter operating in the 1-1.5 GHz range has been demonstrated. These filters (0.3*0.3*0.02 in) have a bandwidth of 30 MHz at 1 GHz and an insertion loss of about 1 dB. The small size serves to provide good shock and acceleration tolerance. Preliminary results on a stacked FBAR filter operated in high overtone mode show response up to 5.5 GHz. The authors review the development of FBAR technology, including piezoelectric film and membrane materials, fabrication techniques, temperature compensation schemes, and the progress made in processing monolithic filters. Issues relating to integration of FBARs with active circuits and IC processing compatibility are addressed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Pore Design of Two-Dimensional Coordination Polymers toward Selective Adsorption (2013)

We have synthesized four porous coordination polymers (PCPs) using Zn(2+), 4,4'-sulfonyldibenzoate (sdb), and four types of dinitrogen linker ligands, 1,4-diazabicyclo[2,2,2]octane (dabco), 1,4-bis(4-pyridyl)benzene (bpb), 3,6-bis(4-pyridyl)-1,2,4,5-tetrazine (bpt), and 4,4'-bipyridyl (bpy). The bent sdb ligands form a rhombic space connected by zinc paddle-wheel units to form a one-dimensional double chain, and each dinitrogen ligand linked the one-dimensional double chains. There are different assembled structures of two-dimensional sheets with the same connectivities between Zn(2+) and the organic ligands. [Zn2(sdb)2(dabco)]n (1) has a noninterpenetrated and noninterdigitated structure, [Zn2(sdb)2(bpb)]n (2) and [Zn2(sdb)2(bpt)]n (3) have interdigitated structures, and [Zn2(sdb)2(bpy)]n (4) has an interpenetrated structure. The length of the dinitrogen ligands dominated their assembled structures and flexibility, which influence the adsorption properties. The flexible frameworks of 2 and 3 provide different stepwise adsorption behaviors for CO2, CH4, C2H6, and C2H4 affected by their pore diameters and the properties of the gases. Their different adsorption properties were revealed by IR spectroscopy and X-ray analysis under a gas atmosphere. The framework of 4 possesses less flexibility and a smaller void space than the others and a negligible amount of CH4 was adsorbed; however, 4 can adsorb either C2H6 or C2H4 through the gate-opening phenomenon. Measurement of the solid-state (2)H NMR was also carried out to investigate the relationship between the framework structure and the dynamics of bpy with regard to the lower flexibility of 4. We have demonstrated a strategy to control the pore size and assembled structures toward selective adsorption properties of PCPs.