gebhart/patrepeval huggingface dataset:
Desempenho e Previsões de um Modelo Regional Estatístico para a Região Sul do Brasil (2000)

A variabilidade climática sazonal e inter-anual afetam as atividades agrícolas, com conseqüências na produção de grãos da Região Sul do Brasil. Essa dependência dos fatores climáticos motivou o desenvolvimento de um modelo regional climático. Esse modelo é chamado de SIMOC (Sistema de Modelagem dos Oceanos) e foi adaptado para prever anomalias sazonais de precipitação. O SIMOC baseia-se em uma técnica estatística denominada de Análise de Correlações Canônicas (ACC). Os preditores para esse modelo são os campos de Temperatura da Superfície do Mar (TSM) em áreas sobre os oceanos Pacífico e Atlântico Tropical e o preditando é a precipitação sobre a Região Sul do Brasil. Os resultados do modelo, usando-se somente o Oceano Atlântico como preditor, pareceu influir mais na precipitação quando essa se afasta da condição inicial. O Oceano Pacífico previu melhor nos meses mais próximos a condição inicial, ao contrário do caso anterior onde usou-se o Atlântico como preditor. Em geral, o uso dos dois oceanos simultaneamente como campo preditor melhorou sensivelmente a precisão das previsões quando comparado com os casos dos oceanos individuais. Para o episódio ENOS de 1997-1998, o modelo reproduziu razoavelmente bem as anomalias de precipitação observadas, mostrando o potencial do SIMOC em previsões sazonais climáticas para a região Sul do Brasil.
From Trigonal Bipyramidal to Platonic Solids: Self-Assembly and Self-Sorting Study of Terpyridine-Based 3D Architectures (2014)

Using a series of tritopic 2,2':6',2″-terpyridine (tpy) ligands constructed on adamantane, three discrete 3D metallo-supramolecular architectures were assembled, i.e., trigonal bipyramidal, tetrahedron, and cube. The self-assembly used tritopic ligands as corner directing units and metal ions as glue units at the edge. The angles of the linkers between adamantane and tpy head play a critical role in guiding the assembled structures, which have the general formula of M3nL2n, where M denotes metal ion and L denotes ligand. All complexes were fully characterized by (1)H, (13)C NMR, diffusion-ordered NMR spectroscopy, ESI-MS, and traveling-wave ion mobility-mass spectrometry. The binary mixtures of LA and LC or LB and LC underwent a self-sorting process that led to the self-assembly of discrete 3D structures. The self-sorting behavior is solely based on the angles precoded within the arm of tritopic ligands. Moreover, kinetic study of preassembled cube and tetrahedron demonstrated a slow ligand exchange process toward a statistical mixture of hetero tetrahedrons with LA and LB.
Passivity Enforcement Using an Infeasible-Interior-Point Primal-Dual Method (2008)

Application of the network equivalent concept for external system representation in electromagnetic transient studies is well known. However, the challenge in application of an equivalent model, approximated by rational functions, is to guarantee passivity of the corresponding model. Therefore, there is a need to enforce passivity of the equivalent model. In this paper, the passivity enforcement problem is first formulated as a <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">quadratic</i> <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">programming</i> (QP) problem, and then solved based on an efficient implementation, using an infeasible-interior-point primal-dual method. An application of this method for passivity enforcement of a six-port admittance model (with large passivity violations) demonstrates its effectiveness and computational efficiency.
Enhanced just-in-time plus protocol for optical burst switching networks (2010)

We propose a new one-way resource reservation protocol for optical burst switching (OBS) networks, called Enhanced Just-in-Time Plus (E-JIT+). The protocol is described in detail, and its formal specification is presented, following an extended finite state machine approach. The performance evaluation of E-JIT+ is analyzed in comparison with other proposed OBS protocols (JIT+ and E-JIT) for the following network topologies: rings; degree-two, degree-three, and degree-four chordal rings; mesh-torus; NSFNET; ARPANET; FCCN-NET; and the European Optical Network. We evaluate and compare the performance of the different protocols in terms of burst loss probability, taking into account the most important OBS network parameters. It was shown that E-JIT+ performs better than available one-way resource reservation protocols for all the evaluated network topologies. Moreover, the scalability of E-JIT+ was observed, and when the network traffic increases, the burst loss probability also increases, leading to a worse network performance.
Supplemental Table 1 from The Novel IKK2 Inhibitor LY2409881 Potently Synergizes with Histone Deacetylase Inhibitors in Preclinical Models of Lymphoma through the Downregulation of NF-κB (2023)

&lt;p&gt;Supplemental Table 1. IC50 of LY2409881 in lymphoma cell lines.&lt;/p&gt;
PORTS: a parallel, optimistic, real-time simulator (1994)

This paper describes issues concerning the design of an optimistic parallel discrete event simulation system that executes in environments that impose real-time constraints on the simulator's execution. Two key problems must be addressed by such a system. First the timing characteristics of the parallel simulator must be sufficiently predictable to allow one to guarantee that real-time deadlines for completing simulation computations will be met. Second, the optimistic computation must be able to interact with its surrounding environment with as little latency as possible, necessitating rapid commitment of I/O operations.
Evaluation under diverse conditions of a differential host reaction scale to Tomato yellow leaf curl virus in tomato (2017)

Tomato yellow leaf curl virus (TYLCV) is the most widespread virus species causing Tomato yellow leaf curl disease. Accurate methods for assessment of resistance are requisite in breeding programs. Researchers at the Volcani Center (Israel) developed a scale of differential TYLCV reactions in seven non-segregating tomato host lines, with virus responses ranging from susceptible to highly resistant. In the present work, this scale has been evaluated with inoculation and assessment methods routinely used by two different research groups, in Spain and Cuba. Different TYLCV isolates, inoculation methods, plant ages, and environmental conditions were compared. Symptom scores of the tomato lines were generally lower in the conditions assayed in both locations than those originally described. Reaction ranking order of the standard tomato lines was more similar to the original description in the assays carried out in Spain. However, response of the lines to TYLCV obtained in both locations did not correspond to scale grades for most of the conditions. A large difference between symptom scores in the susceptible and the resistant lines was observed, with the range in the resistant lines being narrow. These results indicate that the number of standard lines used could be reduced, selecting the most susceptible and the most resistant lines, and one with intermediate resistance. All the factors evaluated affected symptom development. This highlights the importance of establishing a standard inoculation method, experimental conditions, evaluation period and appropriate resistance evaluation criteria, to ensure precise evaluation of genotype responses.
Multiple Pitch Estimation Using Non-Homogeneous Poisson Processes (2011)

Novel statistical models are proposed and developed in this paper for automated multiple-pitch estimation problems. Point estimates of the parameters of partial frequencies of a musical note are modeled as realizations from a non-homogeneous Poisson process defined on the frequency axis. When several notes are combined, the processes for the individual notes combine to give a new Poisson process whose likelihood is easy to compute. This model avoids the data-association step of linking the harmonics of each note with the corresponding partials and is ideal for efficient Bayesian inference of unknown multiple fundamental frequencies in a signal.
Influence of Substrates on the Long-Range Order of Photoelectrodeposited Se–Te Nanostructures (2019)

The long-range order of anisotropic phototropic Se-Te films grown electrochemically at room temperature under uniform-intensity, polarized, incoherent, near-IR illumination has been investigated using crystalline (111)-oriented Si substrates doped degenerately with either p- or n-type dopants. Fourier-transform (FT) analysis was performed on large-area images obtained with a scanning electron microscope, and peak shapes in the FT spectra were used to determine the pattern fidelity in the deposited Se-Te films. Under nominally identical illumination conditions, phototropic films grown on p<sup>+</sup>-Si(111) exhibited a higher degree of anisotropy and a more well-defined pattern period than phototropic films grown on n<sup>+</sup>-Si(111). Similar differences in the phototropic Se-Te deposit morphology and pattern fidelity on p<sup>+</sup>-Si versus n<sup>+</sup>-Si were observed when the deposition rate and current densities were controlled for by adjusting the deposition parameters and illumination conditions. The doping-related effects of the Si substrate on the pattern fidelity of the phototropic Se-Te deposits are ascribable to an electrical effect produced by the different interfacial junction energetics between Se-Te and p<sup>+</sup>-Si versus n<sup>+</sup>-Si that influences the dynamic behavior during phototropic growth at the Se-Te/Si interface.
Selected organic pollutant emissions from unvented kerosene space heaters (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleSelected organic pollutant emissions from unvented kerosene space heatersGregory W. Traynor, Michael G. Apte, Harvey A. Sokol, Jane C. Chuang, W. Gene Tucker, and Judy L. MumfordCite this: Environ. Sci. Technol. 1990, 24, 8, 1265–1270Publication Date (Print):August 1, 1990Publication History Published online1 May 2002Published inissue 1 August 1990https://pubs.acs.org/doi/10.1021/es00078a017https://doi.org/10.1021/es00078a017research-articleACS PublicationsRequest reuse permissionsArticle Views121Altmetric-Citations27LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Applications of multi-resolution morphological analysis in ultra high speed protection of transmission line (2005)

A new but effective technique, multi-resolution morphological analysis (MMA) is introduced to protection relay in this paper. An approach to ultra-high-speed (UHS) direction protection of power transmission line is developed based on MMA. In the proposed scheme, a multi-resolution morphological opening-closing (MMOC) filter is used to suppress interference noise mingled with transient travelling wave. After that, a 1-level multi-resolution morphological gradient (MMG) transform is designed to identify the polarities of current and voltage waves, the fault direction is recognized accordingly. The feasibility and efficiency of the proposed UHS directional protection algorithm are verified by a typical 500 kV transmission line model set up by PSCAD/EMTDC. According to the simulation results, the proposed MMOC filter can effectively remove intense noise from the transient waves, including random noise as well as pulse function-type noise, and polarities of the travelling waves can be exactly identified by the MMG transform even under the worst-case scenarios such as close in faults or fault inception angle at zero crossing.
Anti-inflammatory Diets and Quality of Life-Opening Lecture (2015)

"Anti-inflammatory Diets and Quality of Life-Opening Lecture." Journal of the American College of Nutrition, 34(sup1), p. 3
Telomere erosion in human pluripotent stem cells leads to ATR-mediated mitotic catastrophe (2021)

It is well established that short telomeres activate an ATM-driven DNA damage response that leads to senescence in terminally differentiated cells. However, technical limitations have hampered our understanding of how telomere shortening is signaled in human stem cells. Here, we show that telomere attrition induces ssDNA accumulation (G-strand) at telomeres in human pluripotent stem cells (hPSCs), but not in their differentiated progeny. This led to a unique role for ATR in the response of hPSCs to telomere shortening that culminated in an extended S/G2 cell cycle phase and a longer period of mitosis, which was associated with aneuploidy and mitotic catastrophe. Loss of p53 increased resistance to death, at the expense of increased mitotic abnormalities in hPSCs. Taken together, our data reveal an unexpected dominant role of ATR in hPSCs, combined with unique cell cycle abnormalities and, ultimately, consequences distinct from those observed in their isogenic differentiated counterparts.
Revolutionizing Medical Data Sharing Using Advanced Privacy-Enhancing Technologies: Technical, Legal, and Ethical Synthesis (2021)

Multisite medical data sharing is critical in modern clinical practice and medical research. The challenge is to conduct data sharing that preserves individual privacy and data utility. The shortcomings of traditional privacy-enhancing technologies mean that institutions rely upon bespoke data sharing contracts. The lengthy process and administration induced by these contracts increases the inefficiency of data sharing and may disincentivize important clinical treatment and medical research. This paper provides a synthesis between 2 novel advanced privacy-enhancing technologies-homomorphic encryption and secure multiparty computation (defined together as multiparty homomorphic encryption). These privacy-enhancing technologies provide a mathematical guarantee of privacy, with multiparty homomorphic encryption providing a performance advantage over separately using homomorphic encryption or secure multiparty computation. We argue multiparty homomorphic encryption fulfills legal requirements for medical data sharing under the European Union's General Data Protection Regulation which has set a global benchmark for data protection. Specifically, the data processed and shared using multiparty homomorphic encryption can be considered anonymized data. We explain how multiparty homomorphic encryption can reduce the reliance upon customized contractual measures between institutions. The proposed approach can accelerate the pace of medical research while offering additional incentives for health care and research institutes to employ common data interoperability standards.
A Synthetic Loop Replacement Peptide That Blocks Canonical NF‐κB Signaling (2016)

Aberrant canonical NF-κB signaling is implicated in diseases from autoimmune disorders to cancer. A major therapeutic challenge is the need for selective inhibition of the canonical pathway without impacting the many non-canonical NF-κB functions. Here we show that a selective peptide-based inhibitor of canonical NF-κB signaling, in which a hydrogen bond in the NBD peptide is synthetically replaced by a non-labile bond, shows an about 10-fold increased potency relative to the original inhibitor. Not only is this molecule, NBD2, a powerful tool for dissection of canonical NF-κB signaling in disease models and healthy tissues, the success of the synthetic loop replacement suggests that the general strategy could be useful for discovering modulators of the many protein-protein interactions mediated by such structures.
An Analog 2-D DCT Processor (2006)

This paper presents a simple and low-cost analog architecture for computing 2-D discrete cosine transform (2-D DCT). The proposed circuit is aimed for low-power or very high-speed moderate image quality video compression applications. The design uses current-mode signaling and has two separate 1-D DCT kernels, thus no memory is needed for storing intermediate results. Moreover, the circuit works in continuous time. Simple current mirrors have been used to realize all the needed matrix operations and the transistors are dimensioned in such a way that current level of 20 muA is not exceeded to ensure low-power operation. A prototype chip which includes both 4-point and 8-point forward transforms has been fabricated in a 0.18-mum digital CMOS technology. The operation of the circuit is analyzed with help of measurement results obtained from test chips
Code of practice in geophysics - session 2: guide to the suitability of geophysical methods and techniques to applications relating to the surface and the subsurface (1992)

Quality, "a set of properties and characteristics belonging to a product or a service which endow it with the aptitude to satisfy expressed or implicit requirements" , is of major importante for modern economies.
A multitransmit external body array combined with a 1H and 31P endorectal coil to enable a multiparametric and multimetabolic MRI examination of the prostate at 7T (2019)

We developed a setup with a <sup>31</sup> P transceiver and <sup>1</sup> H Rx endorectal coil in combination with an 8-channel transceiver external body array coil and demonstrated its safety and feasibility for obtaining multiparametric imaging and <sup>1</sup> H and <sup>31</sup> P MRSI at 7T in patients with prostate cancer within one MR examination.
Automated spike sorting algorithmbased on Laplacian eigenmaps andk-means clustering (2011)

This study presents a new automatic spike sorting method based on feature extraction by Laplacian eigenmaps combined with k-means clustering. The performance of the proposed method was compared against previously reported algorithms such as principal component analysis (PCA) and amplitude-based feature extraction. Two types of classifier (namely k-means and classification expectation-maximization) were incorporated within the spike sorting algorithms, in order to find a suitable classifier for the feature sets. Simulated data sets and in-vivo tetrode multichannel recordings were employed to assess the performance of the spike sorting algorithms. The results show that the proposed algorithm yields significantly improved performance with mean sorting accuracy of 73% and sorting error of 10% compared to PCA which combined with k-means had a sorting accuracy of 58% and sorting error of 10%.A correction was made to this article on 22 February 2011. The spacing of the title was amended on the abstract page. No changes were made to the article PDF and the print version was unaffected.
A MEANS OF INCREASING THE TUBERCULOSTATIC EFFECT OF KNOWN CHEMOTHERAPEUTIC AGENTS (1948)

By incorporating a known tuberculostatic agent on one end of a surface-active molecule, an increased in vitro effect on the tubercle bacillus has been obtained. This activity is presumably due to the concentration of the drug molecules at or beneath the mycobacterial cell boundary. Whether the surface-active drug actually penetrates the lipid, or lipoprotein complex that is so characteristic of the mycobacteria is only problematic. According to comparable purely physical-chemical experiments, such a penetration is quite likely. Increase in tuberculostatic effect of over 1000-fold has been attained by rendering surface-active the drugs included in this study. The quantitative evaluation of this increase in activity has been obtained by measuring drug action both when its surface-active properties are functional, and when these properties have been selectively abolished by a specific surface-active antagonist. It is believed that the molecular orientation of a surface-active drug about a bacterial cell accounts for one component of its antibacterial action. Certain previously described surface-active antituberculous drugs and antibiotics have been examined in light of this interpretation. It may be anticipated that the more potent tuberculostatic drugs such as streptomycin could be made more effective by incorporating the molecule into a surface-active compound, according to the principles herein described.
Design and Synthesis of 2-Amino-4-methylpyridine Analogues as Inhibitors for Inducible Nitric Oxide Synthase and in Vivo Evaluation of [18F]6-(2-Fluoropropyl)-4-methyl-pyridin-2-amine as a Potential PET Tracer for Inducible Nitric Oxide Synthase (2009)

A series of position-6 substituted 2-amino-4-methylpyridine analogues was synthesized and compounds 9, 18, and 20 were identified as the inhibitors with the greatest potential to serve as PET tracers for imaging inducible nitric oxide synthase (iNOS). [(18)F]9 was synthesized and evaluated in a mouse model of lipopolysaccharide (LPS)-induced iNOS activation. In vivo biodistribution studies of [(18)F]9 indicate higher tracer uptake in the lungs of the LPS-treated mice when compared to control mice. Tracer uptake at 60 min postinjection was reduced in a blocking study using a known inhibitor of iNOS. The expression of iNOS was confirmed by Western blot analysis of lung samples from the LPS-treated mice. MicroPET studies also demonstrated accumulation of radiotracer in the lungs of the LPS-treated mice. Taken collectively, these data suggest that [(18)F]9 shows favorable properties as a PET tracer to image iNOS activation with PET.
Small Angle Neutron Scattering Study of Lysozyme−Sodium Dodecyl Sulfate Aggregates (2003)

The lysozyme−sodium dodecyl sulfate−water system features several interesting aggregation phenomena and is also of interest as it constitutes a model system for mixtures of a charged colloid with an oppositely charged surfactant, as both colloid and surfactant are pure and monodisperse compounds. The structure of such mixed protein−surfactant systems has been investigated by means of SANS contrast variation experiments. Two interesting issues of protein−surfactant aggregation are discussed. First, a new set of data on the structure of the protein−surfactant complex in solution is added to the discussion of whether the model of “beads on a necklace”, “protein decorated micelles”, or “flexible helix” is most appropriate. It is our conclusion that the compact globule of lysozyme does not fit well into any of the mentioned models. Instead, transient clusters of lysozyme−SDS aggregates are proposed for the L1 phase and more strongly bound locally linear clusters for the gel phase. Second, the structure and formation of a homogeneous, transparent gel at room temperature is analyzed and compared to the well-studied heat-set globular gels. The gel structure in different ionic strengths, lower than the one caused by naturally occurring buffer salts has also been analyzed and it seems that small amounts of salt render the system a more repulsive character than salt-free conditions. In addition to the equilibrated samples studied with the contrast variation technique, the complexation has been studied over time.