gebhart/patrepeval huggingface dataset:
[Purine compound transport and metabolism in the thymus and spleen lymphocytes of C3HA mice during the growth of hepatoma 22]. (1989)

The purine metabolism was studied in the thymus and spleen lymphocytes of C3HA mice during hepatoma 22 growth in comparison with the transport characteristics of hypoxanthine and inosine in lymphocytes. An increase in the transport of these metabolites from erythrocytes was observed in the early hepatoma growth period. It may be associated with a certain pattern in the dynamics of purine metabolic pool in the lymphocytes. The inverse relationship is found between the rates of hypoxanthine transport into thymocytes and its intracellular concentration.
Diagnosis and Treatment of Stress Fractures Located at the Mid-Tibial Shaft in Athletes (1991)

Anterior mid-tibial stress fractures are a clinical problem. The diagnosis can be delayed because the normal radiographic anteroposterior and side views may only show thickening of the anterior cortex. Oblique views and tomography are often required. Isotope scan confirms the diagnosis and is the method of choice. The treatment varies from rest to operational intervention. A delayed union of this area of the tibia is a potential complication and is a high risk for an athlete, a complete fracture being the most serious complication. We present the results of conservative and operative treatment of 17 patients. Of these cases, nine progressed to a delayed union and operation was performed using transversal drilling with a 2.0-2.5 drill. We recommend a period of rest up till six months and surgical intervention with drilling of the hypertrophied cortex if there is any suspicion of a possibility of a delayed union. Also, if there is a long delay in the diagnosis, operative treatment is recommended. Biopsy is recommended during surgery for differential diagnosis.
Cytokinetic properties of asynchronous and cytosine arabinoside perturbed murine tumors measured by simultaneous bromodeoxyuridine/DNA analyses (1985)

This paper describes the determination of cytokinetic properties of asynchronous and cytosine arabinoside- (Ara-C) treated KHT tumors growing in vivo using the bromodeoxyuridine (BrdUrd)/DNA analysis technique. The cytokinetic properties of asynchronously growing tumors were estimated by computer analysis of sequential BrdUrd/DNA distributions measured at 2- to 3-h intervals after administration of a single i.p. injection of BrdUrd. The cytokinetic properties of the Ara-C-treated tumors were estimated by computer analysis of BrdUrd/DNA distributions measured at 2- to 3-h intervals after Ara-C treatment. BrdUrd was injected 30 min prior to tumor harvest. The cytokinetic properties of the cells rendered nonclonogenic by Ara-C were followed in BrdUrd/DNA distributions measured at 2- to 3-h intervals after Ara-C treatment of tumors that were labeled with BrdUrd 30 min prior to Ara C injection. The G1-, S-, and G2M-phase durations were estimated to be 7.6, 10.9, and 2.0 h prior to Ara-C; decreasing to 1.2, 4.1, and 1.4 after Ara-C. The growth fraction was estimated to be 0.8 prior to Ara-C. Complete recruitment of the normally noncycling subpopulation was observed after Ara-C treatment. Ara-C-killed cells were removed from the tumor within 24 h following Ara-C injection. These cytokinetic properties were similar to those reported in other studies.
Degree Formula for Grassmann Bundles (2015)

Let $X$ be a non-singular quasi-projective variety over a field, and let $\mathcal E$ be a vector bundle over $X$. Let $\mathbb G_X({d}, \mathcal E)$ be the Grassmann bundle of $\mathcal E$ over $X$ parametrizing corank $d$ subbundles of $\mathcal E$, and denote by $θ$ the Plücker class of $\mathbb G_X({d}, \mathcal E)$, that is, the first Chern class of the universal quotient bundle over $\mathbb G_X({d}, \mathcal E)$. In this short note, a closed formula for the push-forward of powers of $θ$ is given in terms of the Schur polynomials in Segre classes of $\mathcal E$, which yields a degree formula for $\mathbb G_X({d}, \mathcal E)$ with respect to $θ$ when $X$ is projective and $\wedge ^d \mathcal E$ is very ample.
Novel Power Delivery Network Design and Pre-Silicon Validation Supporting Heterogeneous Dies on a Single Package (2022)

Modern server packaging techniques employ different integration techniques to connect several heterogeneous dies on a single package to circumvent die fabrication challenges. The large span of distance between the dies can make power delivery challenging. A single-sided power entry can see a significant voltage drop from the platform voltage regulator (VR) to the package. A novel approach is highlighted in this paper showing the design of a server platform with multi-sided socket pins and multi-sided VR placement. This utilizes the most benefit from the board copper and capacitors. A novel approach to pre-silicon platform validation and correlation is also presented in this paper to validate such a power delivery network (PDN) design. The new approach allows independent loading on the socket and the monitoring of multiple socket test points compared to the conventional single load zone and single test point using voltage regulator test tool (VRTT). This allows verifying the efficacy of a symmetrical PDN design by emulating package power delivery with a VRTT interposer. Measurements and correlation results from pre-silicon transient validation reveal the exciting potential that system designers can co-design VR and platform power delivery to achieve the best overall performance and cost solution.
Effect of Nanotexturing on Increase in Elastohydrodynamic Lubrication Oil Film Thickness (2014)

The effects of nanotexturing on oil film thickness and shape under pointcontact elasto-hydrodynamic lubrication (EHL) conditions were experimentally investigated. A disk-onball friction tester with an optical interferometer was used to measure oil film thickness and to observe the oil film shape. Periodic groove structures with a spiral, perpendicular, or parallel shape and with various groove depths and distances were formed by irradiation of a femtosecond laser onto the surface of steel balls. These nanotextured balls were tested under a load of 20 N and at rotational speeds from 1.0 to 3.0 m/s. Most of the balls with nanotexturing had a thicker oil film than those without texturing. The groove depth and angle were the key parameters determining the thickness of the oil film as they controlled the amount of side leakage of oil from the contact point. Optimization of these parameters resulted in an oil film that was almost twice as thick as that on the ball without texturing.
The quality of life following antireflux surgery (1992)

To improve the quality of life after antireflux surgery, the patient should notice improvement or disappearance of the symptoms leading to the surgery and should not acquire any new symptoms resulting from antireflux surgery. Published accounts of antireflux surgery results vary widely. Part of this variation may be due to nonstandard methods of evaluating symptoms. A system of symptom evaluation is proposed which takes into account the intensity and frequency of symptoms. It is hoped that this system will allow surgeons to refine and improve their techniques and results.
Navigation without GPS: Fake location for mobile phone tracking (2011)

Despite an increasing demand and popularity in the global mobile market, there is still a lot of development work to be done to improve the limitations of mobile devices and network bandwidth. Currently mobile phones provide many useful capabilities such as touch screen, voice dialing, speakerphone, intelligent typing, high capacity camera, Quad-band GSM/GPRS/EDGE as well as high-end features like GPS Navigation. It is obvious that the more advanced features included to the mobile phones, their price would be higher. This paper attempts to provide a new application named as “Fake Location” to enable GPS Navigation on mobile phones at an affordable price for users. Our application enhances both the link layer and the network layer handovers using Fake Location's information driven from the mobile phone's Cell Tower. Currently, GPS application development has a large number of limitations with regard to inefficiency in supporting the indoor positioning of mobile phones. Fake Location uses text files obtained from Cell Tower to simulate the functionalities of a GPS receiver. The motivation behind this research is to fulfill the need for mobile phone users of any model to utilize the profound benefits of applying GPS in order to make an instant identification of the location of mobile phone users. Moreover, the tracking function is also provided to capture the motion from one point to another point via Google Map.
Developing early vulnerable area aggregates for PET detection of beta‐amyloid based on young and middle‐aged adults from the Framingham Heart Study (2022)

Abstract Background As Alzheimer’s clinical trials shift earlier and earlier in the disease process, current global PET measures of beta‐amyloid (Aβ) positivity may be insufficient for detecting the earliest Aβ deposits. Regional PET measures may better detect the earliest deposits. Previous efforts to identify early‐accumulating regions have inferred which regions may be most vulnerable based on older adults. Our aim was to identify early vulnerable areas by looking earlier in the lifespan. Method 235 clinically‐normal adults ages 33‐74 from the Framingham Heart Study (FHS) underwent one time‐point of dynamic Pittsburgh Compound B (PIB) PET (Tab.1). PIB was regionally quantified in Desikan regions using distribution volume ratio (DVR, cerebellar reference). Linear and quadratic (Age + Age 2 ) models were run to determine association of age with region of interest (ROI) PIB DVR, and ROIs with significantly increasing DVRs were selected for the generation of candidate early vulnerable area (EVA) aggregates. Multiple aggregate EVA DVRs (EVA2‐EVA11) were generated by sequential addition of regions in rank order of descending Age 2 estimate. EVA positivity was derived from both full‐sample GMM and &lt; 45 sample mean + 2SD thresholds. Finally, EVA aggregates were tested using an independent cohort of older adults from the Harvard Aging Brain Study (HABS) that were imaged under an identical protocol (n=250, ages 50‐92), computing sensitivity and specificity of each aggregate at baseline to predict progression to global PIB positivity 3 years later. Result Of 35 Desikan regions each evaluated on the left and right, 11 emerged as quadratic age relationships ( p &lt;0.05; Fig.1) and were used to generate EVA aggregates (Fig.2). Independent validation in baseline global PIB‐ individuals from HABS indicated EVA9 and EVA10 best predicted future accumulation (Fig.3). GMM‐based thresholds provided excellent specificity (SP=1.0) but weak sensitivity (SE=0.41) to predict progression to global PIB positivity 3 years later, while the more liberal mean+2SD thresholds improved sensitivity but decreased specificity (SE=0.88, SP=0.88). Conclusion Utilizing lifespan data from FHS, we identified a set of early vulnerable regions that are predictive of future accumulation in an independent sample of older adults. These findings are potentially useful in identifying the earliest deposits of Aβ for use in clinical trial design.
Copper‐Catalyzed Synthesis of Aryl Azides and 1‐Aryl‐1,2,3‐triazoles from Boronic Acids. (2007)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Association of Acute Kidney Injury With Concomitant Vancomycin and Piperacillin/Tazobactam Treatment Among Hospitalized Children (2017)

Coadministration of IV vancomycin and piperacillin/tazobactam may increase the risk of AKI in hospitalized children. Pediatricians must be cognizant of the potential added risk of this combination therapy when making empirical antibiotic choices.
Analysis and performance evaluation of new coding options for space telecommand links ‐ Part I: AWGN channels (2014)

Summary We investigate and compare, over the additive white Gaussian noise channel, different options for updating the error correcting code currently used in space mission telecommand links. Besides some more consolidated proposals, using low‐density parity‐check codes, we characterize and assess the performance of alternative schemes, based on parallel turbo codes and soft‐decision decoded Bose‐Chaudhuri‐Hocquenghem (BCH) codes. The analysis considers relevant metrics like the codeword error rate, the frame error rate, and the undetected frame error rate. The considered codes include binary and non‐binary low‐density parity‐check codes, parallel turbo codes and extended BCH codes, with different decoding algorithms. The complexity of the various schemes and possible limits for their application are considered and discussed. Several numerical examples are provided. International Journal of Satellite Communications and Networking . Copyright © 2014 John Wiley &amp; Sons, Ltd.
Design and rationale of the MR-INFORM study: stress perfusion MRI to guide the management of patients with stable coronary artery disease (2012)

Background Coronary angiography and the extent of coronary luminal stenosis has historically been the main factor used in guiding decisions regarding revascularisation in patients with stable coronary artery disease. More recently, revascularisation based on invasive fractional flow reserve (FFR) measurements has been shown to result in a significant benefit for event free survival. Cardiac magnetic resonance (CMR) perfusion imaging has been shown to be superior to nuclear perfusion imaging and has the potential to become the non-invasive test of choice. Methods The MR-INFORM study is a prospective, multi-centre, randomized controlled, non-inferiority, outcome trial. It will compare the efficacy of the two investigative strategies for the management of patients with suspected coronary artery disease. Patients presenting with stable angina are randomized into two groups: The FFRINFORMED and the MR-INFORMED group (Figure 1). All patients undergo CMR perfusion scanning at 1.5T (various vendors) at baseline. The patients in the MRINFORMED arm of the trial will have their subsequent management based on the results of the CMR scan. Those patients with significant ischaemia will have coronary angiography and revascularisation guided by the results of the MR scan i.e stenting in arteries that demonstrate ischaemia . All patients with non-significant ischaemia will have medical therapy optimized. The baseline scan in the FFR-INFORMED arm will remain blinded and the patient will go on to have coronary angiography with FFR measurement in those arteries with a stenosis of 40 - 99%. The revascularisation decision in this group will be based on an FFR<0.8 below which a stenosis is physiologically significant. All patients will have a cardiovascular risk assessment at
Measurement of the field evaporation rate of several transition metals (1978)

The field dependence of the field evaporation rate of surface layers has been measured for several transition metals. From the data, the polarisability and the effective distance to the metal surface of kink-site atoms are derived.
The Longitudinal Assessment of Neuropsychiatric Symptoms in Mild Cognitive Impairment and Alzheimer’s disease and their Association with White Matter Hyperintensities in the National Alzheimer’s Coordinating Center’s Uniform Data Set (2019)

ABSTRACT Introduction Neuropsychiatric symptoms (NPS) are common in all dementias, including those with Alzheimer’s disease (AD). NPS contribute to patients’ distress, caregiver burden, and can lead to institutionalization. White matter hyperintensities (WMH) are a common finding on MRI usually indicative of cerebrovascular disease and have been associated with certain NPS. The aim of this study was two-fold. Firstly, we assessed the relationship between WMH load and NPS severity in MCI due to AD (MCI-AD) and AD. Secondly, we assessed the ability of WMH to predict the development and progression of NPS in these participants. Data was obtained from the National Alzheimer’s Coordinating Center. Methods WMH were obtained from baseline MRIs and quantified using an automated segmentation technique. NPS were measured using the Neuropsychiatric Inventory (NPI). Mixed effect models and correlations were used to determine the relationship between WMH load and NPS severity scores. Results Cross-sectional analysis showed no significant association between NPS and WMH at baseline. Longitudinal mixed effect models, however, revealed a significant relationship between increase in NPI total scores and baseline WMH load (p=0.014). There was also a significant relationship between increase in irritability severity scores over time and baseline WMH load (p= 0.009). Trends were observed for a relationship between increase in agitation severity scores and baseline WMH load (p=0.058). No other NPS severity scores were significantly associated with baseline WMH load. The correlation plot analysis showed that baseline whole brain WMH predicted change in future NPI total scores (r=0.169, p=0.008). Baseline whole brain WMH also predicted change in future agitation severity scores (r= 0.165, p= 0.009). The temporal lobe WMH (r=0.169, p=0.008) and frontal lobe WMH (r=0.153, p=0.016) contributed most to this this change. Conclusion Irritability and agitation are common NPS and very distressful to patients and caregivers. Our findings of an increase in irritability severity over time as well as higher agitation severity scores at follow-up in participants with MCI-AD and AD with increased WMH loads have important implications for treatment, arguing for aggressive treatment of vascular risk factors in patients with MCI-AD and AD.
Load Forecasting in District Heating Systems Using Stacked Ensembles of Machine Learning Algorithms (2021)

For district heating, heat demand forecasting is playing a key role for an optimised power plant dispatch. Machine Learning can help to significantly improve forecasts of thermal loads. The prediction quality of neural networks is higher than that of decision trees in most cases. However, compared to decision trees neural networks have weaknesses when extrapolating outside known ranges. This work presents a novel method called "Deep DHC" (Deep Learning for District Heating and Cooling), which combines these two approaches in order to benefit from strengths of both methods. On the one hand, the novel approach uses conventional decision tree based regression algorithms such as the AdaBoost and Random Forest, as well as artificial neural networks. In addition to common feed forward neural networks (FNN), a deep learning network structure, which consists of long short-term memory (LSTM) cells, is used for the first time. The LSTM method has already proven to be very powerful in modern speech recognition. In order to achieve best possible heat demand forecasts, the aforementioned methods for load forecasting are combined and weighted by an additional machine learning method. Results show that it is possible to achieve a further improvement in forecasting quality for district heating loads by purposefully combining individual forecasting methods. Hence, mean and absolute deviations are significantly reduced in comparison to the individual methods.
Overview and Design of Mixed-Voltage I/O Buffers With Low-Voltage Thin-Oxide CMOS Transistors (2006)

Overview on the prior designs of the mixed-voltage I/O buffers is provided in this work. A new 2.5/5-V mixed-voltage I/O buffer realized with only thin gate-oxide devices is proposed. The new proposed mixed-voltage I/O buffer with simpler dynamic n-well bias circuit and gate-tracking circuit can prevent the undesired leakage current paths and the gate-oxide reliability problem, which occur in the conventional CMOS I/O buffer. The new mixed-voltage I/O buffer has been fabricated and verified in a 0.25-mum CMOS process to serve 2.5/5-V I/O interface. Besides, another 2.5/5-V mixed-voltage I/O buffer without the subthreshold leakage problem for high-speed applications is also presented in this work. The speed, power consumption, area, and noise among these mixed-voltage I/O buffers are also compared and discussed. The new proposed mixed-voltage I/O buffers can be easily scaled toward 0.18- mum (or below) CMOS processes to serve other mixed-voltage I/O interfaces, such as 1.8/3.3-V interface
The WILDTRACK Multi-Camera Person Dataset (2017)

People detection methods are highly sensitive to the perpetual occlusions among the targets. As multi-camera set-ups become more frequently encountered, joint exploitation of the across views information would allow for improved detection performances. We provide a large-scale HD dataset named WILDTRACK which finally makes advanced deep learning methods applicable to this problem. The seven-static-camera set-up captures realistic and challenging scenarios of walking people. Notably, its camera calibration with jointly high-precision projection widens the range of algorithms which may make use of this dataset. In aim to help accelerate the research on automatic camera calibration, such annotations also accompany this dataset. Furthermore, the rich-in-appearance visual context of the pedestrian class makes this dataset attractive for monocular pedestrian detection as well, since: the HD cameras are placed relatively close to the people, and the size of the dataset further increases seven-fold. In summary, we overview existing multi-camera datasets and detection methods, enumerate details of our dataset, and we benchmark multi-camera state of the art detectors on this new dataset.
Update on epidemiology and diagnosis of porcine proliferative enteropathy (2004)

roliferative enteropathy (PE) is an enteric disease that occurs in pigs 1 and a number of other species. 2 The etiologic agent of PE in swine is the obligatory intracellular bacterium Lawsonia intracellularis. [3][4]4][5][6] The disease in pigs, commonly referred to as ileitis, occurs in two major clinical forms.Acute hemorrhagic diarrhea and sudden death of replacement animals and finishing pigs close to market age is known as proliferative hemorrhagic enteropathy (PHE); and chronic, mild diarrhea with poor growth performance in grower-finisher pigs (Figure 1) is known as porcine intestinal adenomatosis (PIA). 1,7
Eco‐Efficient Synthesis of Highly Porous CoCO3 Anodes from Supercritical CO2 for Li+ and Na+ Storage (2017)

An eco-efficient synthetic route for the preparation of high-performance carbonate anodes for Li<sup>+</sup> and Na<sup>+</sup> batteries is developed. With supercritical CO<sub>2</sub> (scCO<sub>2</sub> ) as the precursor, which has gas-like diffusivity, extremely low viscosity, and near-zero surface tension, CoCO<sub>3</sub> particles are uniformly formed and tightly connected on graphene nanosheets (GNSs). This synthesis can be conducted at 50 °C, which is considerably lower than the temperature required for conventional preparation methods, minimizing energy consumption. The obtained CoCO<sub>3</sub> particles (ca. 20 nm in diameter), which have a unique interpenetrating porous structure, can increase the number of electroactive sites, promote electrolyte accessibility, shorten ion diffusion length, and readily accommodate the strain generated upon charging/discharging. With a reversible capacity of 1105 mAh g<sup>-1</sup> , the proposed CoCO<sub>3</sub> /GNS anode shows an excellent rate capability, as it can deliver 745 mAh g<sup>-1</sup> in 7.5 min. More than 98 % of the initial capacity is retained after 200 cycles. These properties are clearly superior to those of previously reported CoCO<sub>3</sub> -based electrodes for Li<sup>+</sup> storage, indicating the merit of our scCO<sub>2</sub> -based synthesis, which is facile, green, and can be easily scaled up for mass production.
Supplementary Figure 3 from Endoplasmic Reticulum Stress in the Proapoptotic Action of Edelfosine in Solid Tumor Cells (2023)

Supplementary Figure 3 from Endoplasmic Reticulum Stress in the Proapoptotic Action of Edelfosine in Solid Tumor Cells