gebhart/patrepeval huggingface dataset:
Friction Factor Under Transient Flow Condition (2004)

The modeling of transient flow in suction and discharge systems plays an important role in the simulation of reciprocating compressors. Frequently, a one-dimensional formulation is adopted for the governing equations, with the wall shear stress being evaluated from friction factor correlations developed for stationary flow conditions. The present work reports a numerical analysis of fully developed pulsating flow through pipes, designed to investigate transient effects on the flow velocity profile and wall shear stress. A finite volume methodology is employed to integrate and solve the differential equations, with turbulence being taken into account through the 'eddy' viscosity k-e v 2 f model of Durbin (1991). Flow field results are presented for different transient conditions and discussed in the paper. The presence of transients is seen to affect the wall shear stress to such an extent that friction factor correlations developed for stationary condition are no longer valid.
Treatment for Multiple Early Gastric Cancer. (1995)

早期胃癌多発病巣例の治療法の選択について, 胃切除例および内視鏡治療例から検討した. 多発病巣例は43例で, 単発癌807例に比べて高齢者, 男性が多く, 病型はIIcが多数を占めたが, 隆起型癌 (30.2%), 分化型癌 (83.7%) の頻度が高かった. 深達度は, 主病巣は67.4%がsm癌で, 副病巣は86.9%がm癌であった. リンパ節転移は主病巣smの3例に認められたが, 単発癌と大差はなかった. 局在はM, A領域に多かった. D2郭清の頻度は41.2%であったが, 遠隔成績は単発癌と同等であった. 内視鏡治療例は良好な経過を示したが, 同時性, 異時性の癌腫, 腺腫への配慮の重要性が示された.分析の結果. 多発病巣例に対しても巣発癌に準じて, 開腹縮小手術・標準手術, 内視鏡的粘膜切除術, 腹腔鏡下手術の選択的適応が可能であると判断された.
Abstract 66: BCG can subvert patients antitumor immune response by downregulating HLA-I expression on cancer cells (2021)

Abstract Patients with high-risk non muscle-invasive bladder cancer (NMIBC) frequently relapse after standard BCG immunotherapy and have a dismal outcome after progression to muscle-invasive bladder cancer (MIBC). The mechanisms of tumor resistance to such immunotherapy remain elusive. We performed functional assays of fresh bladder tumors mixed with BCG, reinforced with in vitro experiments and in situ immune profiling of a cohort of MIBC pre- and post BCG therapy. Here, we demonstrate two distinct patterns of BCG-induced immune subversion. In the first pattern, intracellular BCG infection was associated with HLA-I loss and epithelial-to- mesenchymal transition (EMT) characteristics. HLA-I deficient tumors displayed a myeloid immunosuppressive microenvironment and dismal outcomes. Conversely, HLA-I+ BCG-treated tumors generated a Th1 type of immune response associated with an upregulation of exhaustion markers. Such patients had a very favorable outcome upon radical surgery. We surmise that HLA-I expression in bladder cancers does not result from immunoediting but rather from a BCG-induced EMT process that predicts dismal prognosis. Cancer cells HLA-I scoring by immunohistochemistry (IHC) staining can be easily implemented by pathologists in routine practice in order to stratify future urothelial cancer patient treatment strategies. Citation Format: Mathieu Rouanne, Julien Adam, Camélia Radulescu, Séverine Mouraud, Delphine Bredel, Diane Letourneur, Tuan Zea Tan, Nicolas Signolle, Amélie Bigorgne, Michael Dussiot, Sandrine Susini, Lambros Tselikas, François-Xavier Danlos, Roman Chabanon, Anna K. Schneider, Sophie Vacher, Thierry Lebret, Ivan Bièche, Yves Allory, Jean-Charles Soria, Jean Paul Thiery, Laurence Zitvogel, Aurélien Marabelle. BCG can subvert patients antitumor immune response by downregulating HLA-I expression on cancer cells [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2021; 2021 Apr 10-15 and May 17-21. Philadelphia (PA): AACR; Cancer Res 2021;81(13_Suppl):Abstract nr 66.
Performance Analysis of Self-Excited, Pulsed MHD Power System (1998)

Performance characteristics of self-excited pulsed MHD power systems are investigated with one-dimensional time-dependent calculations using a gas-liquid two-fluid model. At first, Russian pulsed MHD power system 'Pamir-3U' is analyzed. The result of numerical simulations of hot-fire tests shows good agreement with the experimental data, confirming the validity of the mathematical model. Performance analysis of Pamir-3U reveals that the power output is approximately constant with the variation of load resistance, while the ballast resistor consumes large electric power. It is also shown that the system has been optimally designed to supply large load current. Next, a new system yielding larger power output is proposed and analyzed. The obtained characteristics show that the new system can provide the maximum power output of 25MW, which is larger than 15MW of Pamir-3U.
Triarylboron‐Based Fluorescent Organic Light‐Emitting Diodes with External Quantum Efficiencies Exceeding 20 % (2015)

Abstract Triarylboron compounds have attracted much attention, and found wide use as functional materials because of their electron‐accepting properties arising from the vacant p orbitals on the boron atoms. In this study, we design and synthesize new donor–acceptor triarylboron emitters that show thermally activated delayed fluorescence. These emitters display sky‐blue to green emission and high photoluminescence quantum yields of 87–100 % in host matrices. Organic light‐emitting diodes using these emitting molecules as dopants exhibit high external quantum efficiencies of 14.0–22.8 %, which originate from efficient up‐conversion from triplet to singlet states and subsequent efficient radiative decay from singlet to ground states.
XF-73, a novel antistaphylococcal membrane-active agent with rapid bactericidal activity (2009)

XF-73 exhibited rapid membrane-perturbing activity, which is likely to be responsible for inhibition of macromolecular synthesis and the death of staphylococci exposed to the drug.
Modified Runlength Coding for Improved JPEG Performance (2007)

A number of image compression systems have been developed to save storage space and transmission bandwidth. The field of image compression has witnessed a lot of research on improving JPEG or evolving a codec with better performance. In the JPEG standard, run length encoding is used to code the string of zeros resulting from crude quantization of AC coefficients. In this paper we propose modified runlength JPEG (MR-JPEG), which uses separate coding of three symbols (RUNLENGTH, SIZE, AMPLITUDE) to code the information. To compare the results with the earlier scheme, we use two parameters-maximum difference (MD) for perceptual quality measurement and size (in KB's) for compression. Our results show that for large size images (512times512 and above), proposed scheme demonstrates higher compression with better quality.
Design and analysis of an optimized cavity-backed zigzag Archimedean spiral antenna (2010)

This paper presents a two-arm, zigzagged Archimedean spiral antenna with an optimized cavity. A multilayer dielectric absorber has been introduced in the cavity to facilitate unidirectional operation of the antenna. In order to incorporate the frequency-dependent complex permittivity data of the absorbing materials inserted in the cavity, precise microwave instrumentation has been used to determine these parameters experimentally. Based on this data, a genetic algorithm optimization procedure has been applied to derive the most favourable geometry of the absorbing cavity. Our results show that a design thus optimized significantly improves key performance parameters, maximizes the co-polarized gain and minimizes the cross-polarized gain of the antenna across its operational bandwidth.
Supplementary Table S1 from Deep Sequencing Reveals a Novel miR-22 Regulatory Network with Therapeutic Potential in Rhabdomyosarcoma (2023)

&lt;p&gt;miRNAs abundance in RMS and muscle.&lt;/p&gt;
How to Contract Ontologies: Statement of Interest (2012)

Abstract. The dynamic nature of knowledge development has motivated the formal study of ontology evolution problems. In this paper, we study ontology contraction—the problem of retracting information that is no longer considered to hold. Our prime interest is to focus on ontologies expressed in Description Logics DL-Lite and EL, which underpin the OWL 2 QL and OWL 2 EL profiles. Our goal is to understand how to compute contractions under different kinds of semantics. As we have already shown in [1, 2], ontology contraction is technically very challenging. 1 Importance of Ontology Contraction Ontologies written in the Web Ontology Language (OWL) [3] and its revision OWL 2 [4] are becoming increasingly important for a wide range of applications. The formal underpinning of OWL is based on Description Logics (DLs) – knowledge representation formalisms with well-understood computational properties [5]. A DL ontology K consists of a TBox T, describing general (i.e., schema-level) domain knowledge, and an ABox A, providing data about specific individuals.
Cognitive Functions, Attention-Deficit Hyperactivity Disorders, and Alzheimer’s Disease (2008)

Attention-deficit (AD) hyperactivity disorder and Alzheimer’s disease are debilitating neurological disorders that affect patients at both ends of the age spectrum. The histaminergic system in the central nervous system is implicated in the control of wakefulness, and strong preclinical evidence suggests that blockade of histamine H3 receptors can increase wakefulness, decrease impulsivity, and improve attention as well as other cognitive domains. Attentional deficits are observed as increased percentage of errors in operant tasks, whereas impulsivity is observed as the inability of spontaneous hypertensive rats to delay a response to obtain a larger reward. The unmet need in AD treatment extends beyond drugs that provide greater symptomatic relief with fewer side effects, to treatments that will ultimately slow, halt, or reverse the progression of the disease. AD, the most common form of dementia, is a progressive and devastating illness that robs the affected individual of the ability to learn, reason, remember events, and ultimately communicate and perform daily activities.
Longitudinal Effect PLZT Spatial Light Modulators (1993)

This paper presents the design and fabrication aspects of a longitudinal effect PLZT spatial light modulator designed for operation in the visible and near infrared.
An ultrasonic motor using an injection-molded plastic rotor and its application to motor-driven potentiometers (2000)

Ultrasonic motors, used as compact servomotors for precision positioning, have many advantages over electromagnetic motors. However, they have a complicated structure and require a complicated drive circuit, which makes them costly. This study has realized a low-cost ultrasonic motor for application to low-cost products. The first application target was as the motor of a high-voltage focus adjustment potentiometer in a CRT monitor. A motor was fabricated and operated successfully. For the basic type of ultrasonic motors, a piezoelectric revolving resonator (PRR)-type motor was adopted because it simplifies the structure. In addition, the rotor of the main component was produced using injection-molded plastics. This ensured stable generation of the torque, low cost, and good mass productivity. The diameter of the outer rotor was 24 mm and the motor achieved a large holding torque of 150 gf-cm, and a low drive voltage of between 5 and 10 V. An inclined contact coil brush was developed for the motor-driven potentiometer. The coil brush realized stable multipoint contact with a very light load of 10 gf-cm. The rotor and the brush holder were formed integrally, which provided a compact structure. This paper describes structural design of the ultrasonic motor and the motor-driven potentiometer, their operation, and experimental results. © 2000 Scripta Technica, Electron Comm Jpn Pt 2, 83(8): 8–17, 2000
Statistics of Infrared Images (2007)

The proliferation of low-cost infrared cameras gives us a new angle for attacking many unsolved vision problems by leveraging a larger range of the electromagnetic spectrum. A first step to utilizing these images is to explore the statistics of infrared images and compare them to the corresponding statistics in the visible spectrum. In this paper, we analyze the power spectra as well as the marginal and joint wavelet coefficient distributions of datasets of indoor and outdoor images. We note that infrared images have noticeably less texture indoors where temperatures are more homogenous. The joint wavelet statistics also show strong correlation between object boundaries in IR and visible images, leading to high potential for vision applications using a combined statistical model.
Analytic modelling of disk I/O subsystems (1981)

This is a summary of a tutorial presented during the conference discussing a number of approaches to representing disk I/O subsystems in analytic models of computer systems.
Enhancement of the senesitivity of chemical-amplification-type photoimaging materials by .BETA.-tosyloxyketone acetals. (1995)

Chemical amplification photoresists have been attracting much attention owing to the high sensitivity and high resolution. The high sensitivity of this photoimaging materials derives from a catalytic nature of a subsequent "dark" reaction after irradiation (Scheme 1), and there are continuing efforts to enhance the sensitivity. However, thus far the methodology has been solely based on the seeking for a system having larger turnover number of the above reaction. We have been proposing a novel concept of an acid proliferation to enhance the photosensitivity [1-3]. The concept of the acid proliferation is such that the occurrence of a certain reaction or series of reactions, which are catalyzed by an acid, results in the formation of acid molecules leading to the increment of the acid in the manner of geometric progression. A compound that undergoes such a reaction could be termed as an acid amplifier. We have already reported that 2-phenyl-2-(2tosyloxyethyl)-1,3-dioxolane (PTD) acts as the acid amplifier through very simple chemical reactions, namely, the acid catalyzed deacetalization of 1,3-dioxolane and the thermal elimination of p-toluenesulfonic acid (Scheme 2) The addition of PTD enhanced the sensitivity of the photoimaging material which consists of poly(tert-butyl methacrylate) and Biphenyl-4phenylthiophenylsulfonium hexafluoroantimonate (DTS) by 9 times. Here, we report that the addition of PTD to another chemical-amplification-type photoimaging materials also enhances the photosensitivity.
Electrohydrodynamic flow regimes in a cylindrical electrostatic precipitator (2013)

This article presents a model of the electrohydrodynamic fields that occur inside an axisymmetric electrostatic precipitator of the wire/cylinder type under laminar flow conditions. Five relevant dimensionless numbers were identified. Besides two geometrical parameters, these numbers include the electric Reynolds number Ree and the hydrodynamic Reynolds number Rea as well as the ratio Σ between the Peek field and the mean electric field between the two electrodes. The dimensional parameters (maximum electric field, air flow rate to be treated and minimum diameter of particles to be treated) have been expressed in the context of these dimensionless numbers. The numerical simulation carried out revealed four flow regimes, due to the finite length of the electrodes, which differ by the number of secondary flows involved. A detailed analysis shows two areas where some of these regimes coexist. This study provides a basis for making a realistic evaluation of the impact of secondary flows on the collection performance of electrostatic precipitators.
PATOLOGIA MOLECULAR DE LAS APOPROTEINAS (1991)

Las apolipoproteinas (Apo) son glicoproteinas comprometidas con los procesos de ensamblaje, secrecion y metabolismo de las lipoproteinas. Se identifica como familias y se nombran con letras tales como A,B,C,D,E,F,G, y H. Hay variedades, dentro de una misma familia, las cuales se identifican con subindices romanos, verbo y gracia Apo I, Apo II, etc. Las mas conocidas son las Apo A y las Apo B. las Apo A son el principal componente de las HDL mientras que las Apo B son el principal componente de las LDL. Apo B se asocia positivamente al incremento del riesgo  coronario; en cambio Apo A, se asocia inversamente. Se sugiere que la relacion Apo A1/Apo B es el mas eficiente indicador de riesgo y cuanto mas baja es al relacion, mas elevado se considera el riesgo.
Characterization of New ATM Deletion Associated with Hereditary Breast Cancer (2021)

Next-generation sequencing (NGS)-based cancer risk screening with multigene panels has become the most successful method for programming cancer prevention strategies. <i>ATM</i> germ-line heterozygosity has been described to increase tumor susceptibility. In particular, families carrying heterozygous germ-line variants of <i>ATM</i> gene have a 5- to 9-fold risk of developing breast cancer. Recent studies identified <i>ATM</i> as the second most mutated gene after <i>CHEK2</i> in BRCA-negative patients. Nowadays, more than 170 missense variants and several truncating mutations have been identified in <i>ATM</i> gene. Here, we present the molecular characterization of a new <i>ATM</i> deletion, identified thanks to the CNV algorithm implemented in the NGS analysis pipeline. An automated workflow implementing the SOPHiA Genetics' Hereditary Cancer Solution (HCS) protocol was used to generate NGS libraries that were sequenced on Illumina MiSeq Platform. NGS data analysis allowed us to identify a new inactivating deletion of exons 19-27 of <i>ATM</i> gene. The deletion was characterized both at the DNA and RNA level.
Amyloid burden and sleep blood pressure in amnestic mild cognitive impairment (2015)

Attenuated reductions in sleep BP are associated with a greater Aβ burden in the posterior cingulate and altered dynamic CBF regulation in patients with aMCI.
Recrystallization Study of Nb-Bearing HSLA Steels After Laboratory Batch Annealing Using OIM-EBSD Techniques (2016)

Abstract The present work studied the recrystallization kinetics of a Nb-bearing high strength low alloy (HSLA) steel using a fully-computer controlled laboratory batch annealing (BA) process. This work was designed to study the effect of thermo-mechanical processing (TMP), transformation products, and the amount of cold deformation on the kinetics of recrystallization. The amount of deformation above and below the non-recrystallization (Tnr) temperature of the steel used in this study was investigated in terms of the grain boundary character distribution (GBCD) assessed in the hot band condition. The hot band condition was then subjected to 60 % cold deformation prior to the BA studies. The cold rolled samples were placed in the laboratory BA furnace using the simulated cold spot temperature (CST) annealing process. The selected annealing temperature was 650°C and the holding times varied between 15 minutes and 12 h. The central focus of this work was to understand how the TMP schedule affects the GBCD of the hot band; how the frequency of this initial GBCD changes with the amount of cold deformation; and how the steel composition, stored energy, GBCD, and annealing processing parameters influence the annealing behavior of the steel used in this study. Advanced microstructural techniques including orientation imaging microscopy and electron back-scattered diffraction (EBSD) provided the evolution of the GBCD, the changes in stored energy with annealing times. The results of this investigation clearly showed that when the TMP is conducted in a temperature range where the deformation of austenite favors twin formation, leading to higher levels of high angles grain boundaries (HAGB) and special coincidence site lattice (CSL) boundaries, the kinetics of recrystallization are increased. The results of this work were presented and discussed.
Interfaces on the go (2010)

Enabling mobile micro-interactions with physiological computing.
Hazard and Operability (HAZOP) Analysis of Safety-Related Scientific Software (2015)

Hazard and operability (HAZOP) analysis technique is used to identify and analyze hazards and operational concerns of a system. It provides a structured framework that can be used to perform a step-by-step safety analysis of a system. This paper details how to apply this method to safety-related scientific software. In this paper, we have developed (1) a nomenclature that singles out 30 primary concepts (2) a canonic set of abstractions of software programming constructs as a function of the primary concepts; (3) a process of translation from an existing design representation to the target design representation in the form of finite state machines; (4) HAZOP templates for each canonical form; and (5) an input variable prioritization method. We also developed a computational tool that can be used to perform HAZOP analysis of scientific software. Its results are compared with those obtained during manual HAZOP analysis by calculating the value of Shannon entropy, correctness, and the time required to perform each analysis. Overall, this method helps identify useful information about the impact of variables in the code that can then be utilized to develop robust code for making safety-critical decisions.
Increased Total TAU But Not Amyloid-β42; in Cerebrospinal Fluid Correlates with Short-Term Memory Impairment in Alzheimer's Disease (2009)

Given the need for tools for early and accurate diagnosis, prediction of disease progression, and monitoring efficacy of therapeutic agents for AD, the study of cerebrospinal fluid (CSF) biomarkers has become a rapidly growing field of research. Several studies have reported conflicting data regarding the relationships between CSF biomarkers and dementia severity. In this study, we have focused on the identification of CSF biomarkers and their correlations with the impairment of different cognitive domains measured using the Cognitive Abilities Screening Instrument (CASI). Patients with AD (n=28), non-AD dementia (n=16), other neurological disorders (OND, n=14), and healthy controls (HC, n=21) were enrolled. Our results revealed significantly higher CSF total tau (t-tau) and lower amyloid-beta(42) levels in AD patients compared with those in HC and OND groups. Moreover, our data show that CSF t-tau levels, but not Abeta(42) levels, have an inverse correlation with the score of short-term memory in CASI for patients with AD (Spearman: r=-0.444; p=0.018). This data might indicate that the higher CSF t-tau level is associated with more NFT pathology and more severe impairment of short-term memory in AD patients.
Laser diode feedback interferometer for stabilization and displacement measurements (1987)

Active laser diode interferometers in which the interference signal is fed back to the diode current are investigated for Twyman-Green and self-coupling interferometers. The Twyman-Green interferometer is stabilized with a stabilization factor of more than 100. By using the feedback signal of either type of interferometer, displacement is measured in a linear scale over a dynamic range of 8-9,microm with a precision of 10-60 nm. The feedback signal vs displacement shows hysteresis and multistable behavior, in accordance with theoretical results.