gebhart/patrepeval huggingface dataset:
Lactobacillus Plantarum: Characterization of the Species and Application in Food Production (2010)

Abstract Lactobacillus plantarum is a heterofermentative microaerophilic Gram-positive microorganism, with rod morphology, occurring singly or grouped in short chains. This species has well accepted GRAS status and numerous strains of L. plantarum have been isolated from different ecological niches including meat, fish, fruits, vegetables, milk, and cereal products. L. plantarum has been used as a starter culture in various food fermentation processes contributing to the organoleptic properties, flavour, and texture. Due to production of lactic acid and other antimicrobial compounds, L. plantarum also contributes to the safety of the final products. In this article, we overview the history of description of L. plantarum and biochemical properties, methods for identification and applications in food production. Keywords: Lactobacillus plantarum taxonomyapplicationfoods Acknowledgments This research was supported by the Claude Leon Foundation, Cape Town, South Africa and CAPES, Ministry of Education, Brasilia, DF, Brazil.
B�tzinger neurons project towards bulbospinal neurons in the rostral ventrolateral medulla of the rat (1997)

Sympathetic nerve activity often fluctuates with the respiratory cycle, but the central neurons that impose this respiratory modulation have not been conclusively identified. In the present study, we used intracellular recording and dye-filling to identify expiratory neurons in the Bötzinger complex. Our aim was to see if Bötzinger neurons project towards putative cardiovascular neurons in the rostral ventrolateral medulla. In the first series of experiments, histochemistry and immunohistochemistry were used to reveal the labelled Bötzinger neurons and neurons immunoreactive for tyrosine hydroxylase. Two out of four Bötzinger neurons had axon varicosities that were closely apposed to tyrosine hydroxylase-immunoreactive neurons with cell bodies located within 0.6 mm caudal to the facial nucleus (three and five close appositions, respectively). In a second series of studies, rats were injected with cholera toxin B into the intermediolateral cell column of the spinal cord 4-7 days before the electrophysiological recording. Eight of the fourteen labelled Bötzinger neurons had a direct projection towards cholera toxin B-labelled neurons in the rostral ventrolateral medulla. Close appositions were found on both somata and proximal dendrites (5 +/- 2 close appositions/neuron, n = 8). The present study supports the idea that a direct projection from Bötzinger neurons to presympathetic neurons in the rostral medulla plays a role in the respiratory modulation of sympathetic nerve activity.
Solutions to Security and Privacy Issues in Mobile Social Networking (2009)

Social network information is now being used in ways for which it may have not been originally intended. In particular, increased use of smartphones capable of running applications which access social network information enable applications to be aware of a user's location and preferences. However, current models for exchange of this information require users to compromise their privacy and security. We present several of these privacy and security issues, along withour design and implementation of solutions for these issues. Our work allows location-based services to query local mobile devices for users' social network information, without disclosing user identity or compromising users' privacy and security. We contend that it is important that such solutions be acceptedas mobile social networks continue to grow exponentially.
Hypothalamic, Metabolic, and Behavioral Responses to Pharmacological Inhibition of CNS Melanocortin Signaling in Rats (2001)

The CNS melanocortin (MC) system is implicated as a mediator of the central effects of leptin, and reduced activity of the CNS MC system promotes obesity in both rodents and humans. Because activation of CNS MC receptors has direct effects on autonomic outflow and metabolism, we hypothesized that food intake-independent mechanisms contribute to development of obesity induced by pharmacological blockade of MC receptors in the brain and that changes in hypothalamic neuropeptidergic systems known to regulate weight gain [i.e., corticotropin-releasing hormone (CRH), cocaine-amphetamine-related transcript (CART), proopiomelanocortin (POMC), and neuropeptide Y (NPY)] would trigger this effect. Relative to vehicle-treated controls, third intracerebroventricular (i3vt) administration of the MC receptor antagonist SHU9119 to rats for 11 d doubled food and water intake (toward the end of treatment) and increased body weight ( approximately 14%) and fat content ( approximately 90%), hepatic glycogen content ( approximately 40%), and plasma levels of cholesterol ( approximately 48%), insulin ( approximately 259%), glucagon ( approximately 80%), and leptin ( approximately 490%), whereas spontaneous locomotor activity and body temperature were reduced. Pair-feeding of i3vt SHU9119-treated animals to i3vt vehicle-treated controls normalized plasma levels of insulin, glucagon, and hepatic glycogen content, but only partially reversed the elevations of plasma cholesterol ( approximately 31%) and leptin ( approximately 104%) and body fat content ( approximately 27%). Reductions in body temperature and locomotor activity induced by i3vt SHU9119 were not reversed by pair feeding, but rather were more pronounced. None of the effects found can be explained by peripheral action of the compound. The obesity effects occurred despite a lack in neuropeptide expression responses in the neuroanatomical range selected across the arcuate (i.e., CART, POMC, and NPY) and paraventricular (i.e., CRH) hypothalamus. The results indicate that reduced activity of the CNS MC pathway promotes fat deposition via both food intake-dependent and -independent mechanisms.
Development and Characterization of the cobas Human Papillomavirus Test (2013)

ABSTRACT The cobas human papillomavirus (HPV) test, approved by the FDA in April 2011, is a fully automated assay for the detection of 14 high-risk (hr) HPV genotypes from cervical specimens collected in liquid-based cytology medium using real-time PCR amplification of the L1 gene and TaqMan probes. Results are simultaneously reported as positive or negative for the pooled 12 oncogenic HPV types (HPV31, -33, -35, -39, -45, -51, -52, -56, -58, -59, -66, and -68) from channel 1, with HPV16 and HPV18 genotypes read individually from channels 2 and 3. A fourth channel detects the human β-globin gene as a control for sample adequacy and assay inhibition. To optimize clinical sensitivity and specificity, cutoff values (cycle thresholds [ C T ]) were established for each channel based on the detection of cervical intraepithelial neoplasia grade 2 (CIN2) or greater (≥CIN2). For women aged ≥21 years with cytology results indicating atypical squamous cells of undetermined significance (ASC-US), C T values provided a sensitivity of 90% (95% confidence interval [CI], 81.5% to 94.8%) for the detection of ≥CIN2 and a specificity of 70.5% (95% CI, 68.1% to 72.7%). The analytic sensitivity (limit of detection) ranged from 150 to 2,400 copies/ml, depending on genotype. The analytic specificity, evaluated by comparing the HPV result with a combined comparator of Sanger sequencing and the Qiagen digene HC2 high-risk HPV DNA test (hc2), demonstrated overall positive agreement of 96.3% for 14 hrHPV types in women with ASC-US cytology results who were aged ≥21 years and 86.1% in women with NLIM (negative for intraepithelial neoplasia or malignancy) cytology who were aged ≥30 years. These and other performance validation studies demonstrate that the cobas HPV test is a fully automated and clinically validated robust test.
ChemInform Abstract: Fluorination of Aromatic Compounds from 1‐Aryl‐3,3‐dimethyltriazenes and Fluoride Anions in Acidic Medium. Part 2. Synthesis of (S)‐[18F]‐3‐Fluoro‐α‐methylphenylalanine. (2001)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Characteristics of the hydroxyapatite film deposited on human enamel: deposition of a ceramic film by powder jet deposition technique (2008)

A thick film of Hydroxyapatite (HAp) film is experimentally deposited on the enamel and dentin parts of a human tooth, using Powder Jet Deposition (PJD) technique. Micromorphologies of the created film, of the interface between the tooth and deposited film, and also of the tooth itself are studied and elaborated. Finally, possibility of a totally new kind of tooth treatment based on forming a new type of bond between the tooth and biomaterials through recalcification process is introduced.
Effect of Kappa-Casein and Beta-Lactoglobulin Loci on Milk Production Traits and Reproductive Performance of Holstein Cows (2005)

The effects of kappa-casein (kappa-CN) and beta-lactoglobulin (beta-LG) loci on milk production traits (milk, fat, protein, and lactose yield, fat, protein, and lactose content) and reproductive performance (gestation length, calving interval, age at first and second calving, number of services per conception) was estimated for 278 Holstein cows in the first 2 lactations. Genotypes of kappa-CN and beta-LG were determined by alkaline and acidic polyacrylamide gel electrophoresis. Milk production was recorded daily. Single-trait, mixed, linear models were used for the statistical analysis of the data. Results indicated that kappa-CN genotypes affected significantly protein yield and content (genotype AB > genotype AA). A tendency for increased milk and fat yield of animals having AB kappa-CN genotype was also found. Fat content and lactose yield and content were not affected. In the beta-LG system, significant differences were detected for milk yield (AB > AA), fat yield (BB and AB > AA), fat content (BB > AA and AB), and lactose yield (AB > AA). A tendency for higher protein yield was also observed (AB > AA). The beta-LG locus had no significant effect on protein and lactose content. No associations between polymorphisms at the kappa-CN locus and reproductive performance were found. There was a tendency, however, for cows with AB genotype to have older age at first and second calving. In the beta-LG system, cows with AA genotype had significantly shorter gestation length than did those with AB or BB genotype. No differences were detected between beta-LG polymorphisms for the other reproductive traits.
Solvent dependent hyperpolarizability of a merocyanine dye (1978)

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Design of novel efficient full adder architecture for Quantum-dot Cellular Automata technology (2018)

In this paper the novel coplanar circuits for full adder implementation in Quantum-dot Cellular Automata (QCA) technology are presented. We propose a novel one-bit full adder circuit and then utilize this new circuit to implement novel four-bit Ripple Carry Adder (RCA) circuit in the QCA technology. The QCA Designer tool version 2.0.1 is utilized to implement the designed QCA full adder circuits. The implementation results show that the designed QCA full adder circuits have an improvement compared to other QCA full adder circuits.
Correction methods for missing data in sinograms of the HRRT PET scanner (2003)

The high resolution research tomograph (HRRT) is a 3-D PET scanner designed for human brain and small animal imaging. The HRRT consists of eight panel detector heads that are separated by gaps of 17 mm resulting in gaps in the sinogram. Furthermore, gaps can result from detector-block failure. To prevent artifacts in the reconstruction when using Fourier rebinning (FORE), filling the data gaps is required. The purpose of this study was to evaluate the accuracy of three gap filling methods: a) bilinear interpolation of sinogram data; b) a model-based method in which an intermediate volume is reconstructed [2-D ordered subsets expectation maximization (2-D OSEM)] based on direct planes only, after which this image is forward projected to fill the gaps; c) an improved model-based method in which gaps are first filled using interpolation, then reconstructed using FORE + 2-D OSEM and forward projected. The improved model-based method outperforms interpolation, but requires more computation time.
Diode lasers - A different route to high average power (2000)

A number of approaches are currently being used to combine the beams from individual diode laser bars to achieve high average power. The limited number of systems available commercially are based on sophisticated water cooled stacks with varying levels of optical complexity. In these systems, the expected cost reduction benefits of diode lasers have not yet been realized, at least in terms of capital costs. In this paper, a fresh holistic approach to high power diode laser design is presented. This employs a novel approach to thermal management as well as incorporating an optical delivery system with a large working distance. Results on the optical characterization of such a design are presented and the techniques by which higher brightness can easily and cost effectively be achieved are explained.
Rates of Complications and Mortality in Older Patients With Diabetes Mellitus (2013)

Duration of diabetes and advancing age independently predict diabetes morbidity and mortality rates. As long-term survivorship with diabetes increases and as the population ages, more research and public health efforts to reduce hypoglycemia will be needed to complement ongoing efforts to reduce cardiovascular and microvascular complications.
Reliable adaptive modulation and interference mitigation for mobile radio slow frequency hopping channels (2008)

The long range fading prediction algorithm for Slow Frequency Hopping (SFH) systems is proposed and demonstrated to enable combined adaptive modulation and adaptive frequency diversity to mitigate the effects of fading and partial-band interference. Significant performance gains are demonstrated relative to non-adaptive methods in realistic mobile radio SFH channels where the total bandwidth does not exceed approximately 15 times the coherence bandwidth.
Comparison of two approaches for OCT data analysis in white matter imaging (2021)

Log-and-linear fit and depth-resolved approaches for OCT data processing were applied for white matter state evaluation. Both approaches are suitable for this purpose, however, the choice of necessary method depends on features of used OCT device.
Use of pheromone chemistry to identify Grapholita lobarzewskii as an occasional pest of apple and plum (1989)

Abstract As shown by chemical analysis and field trapping, the sex pheromone of Grapholita lobarzewskii consists of a blend of ( E )‐8‐dodecenyl acetate and ( Z )‐8‐dodecenyl acetate. Maximum attractiveness was found at 80–95%. Dodecyl acetate and tetradecyl acetate, both present in the female gland, did not affect trap catch. G. lobarzewskii has recently gained importance as a pest of apple and plum, but has so far been referred to as Grapholita janthinana . The latter is attracted to the same two compounds, but in reversed portions (20% E ). Zusammenfassung Pheromonchemie als Hilfsmittel beider Identifikation von Grapholita lobarzewskii, einem sporadischen Schädling von Apfel und Zwetschge Chemische Analysen und Feldversuche zeigen, dass das Sexualpheromon des Kleinen Fruchtwicklers, G. lobarzewskii aus ( E )‐8‐Dodecenylacetat ( E 8–12: Ac ) und ( Z )‐8‐Dodecenylacetat ( Z 8–12:Ac) besteht. Die grösste Lockwirkung wurde mit einem Gemisch der beiden Substanzen bei einem E ‐Anteil von 80–95% erzielt. Dodecylacetat (12: Ac) und Tetradecylacetat (14: Ac) wurden ebenfalls in den weiblichen Pheromondrüsen nachgewiesen, hatten aber im Freiland keinen Einfluss auf die Lockwirkung. G. lobarzewskii tritt seit einiger Zeit in der Schweiz als Schädling von Apfel und Zwetschge auf und ist an ihrem charakteristischem Frassgang leicht erkennbar. Die Art wurde bisher irrtümlich als G. janthinana bezeichnet. G. janthinana lebt auf Rosaceen, und wird vom gleichen Substanzpaar angelockt, allerdings bei umgekehrtem Mischungsverhältnis (20% E ).
Effects of Antiphospholipid Antibodies on In Vitro Platelet Aggregation (2011)

Antiphospholipid antibodies contribute to the development of thrombosis, although precise mechanisms remain to be elucidated. We determined the effects of affinity-purified anti-beta(2)-glycoprotein 1 (anti-β(2)GP1) and anti-prothrombin (anti-PT) antibodies on in vitro platelet aggregation. Adenosine diphosphate (ADP) and collagen-induced platelet aggregation were performed using platelet-rich plasma ([PRP] 250 × 10(9)/L). Antiphospholipid antibodies (1.25-10 μg/mL) were preincubated with PRP for 10 minutes at 37°C prior to the addition of agonist. Anti-β(2)GP1 antibodies significantly reduced platelet aggregation (percentage area under the curve; %AUC) in a concentration-dependent manner using both 5 μmol/L (P < .001) and 2.5 μmol/L (P = .038) ADP but did not significantly affect the rate of aggregation. Anti-PT antibodies significantly enhanced 5 µg/mL collagen-induced platelet aggregation (%AUC; P = .034) but did not affect ADP-induced platelet aggregation. These results suggest (1) interactions and effects of antiphospholipid antibodies on platelets are agonist and concentration dependent and (2) anti-β(2)GP1 antibodies may inhibit dense granule release and/or inhibition of the arachidonic acid pathway.
A Predictive Movement Based Handover Algorithm for Broadband Wireless Networks (2008)

The design of an efficient handover technique is considered as one of the crucial topics in the cellular-based wireless networks. Feasible handover process can minimize the performance degradation as the mobile device is moving between different base stations. Based on the IEEE 802.16e standard, it is required to provide satisfactory handover performance under a wide-range of moving speeds of the mobile device. In this paper, a predictive movement-based handover (PMHO) algorithm is proposed. Without incurring excessive overheads as from the conventional location estimation and tracking techniques, the proposed sideline-traveling scheme within the PMHO algorithm employs the moving state indicator (MSI) to predict the potential moving characteristics of the mobile device. The handover decision of the PMHO approach is determined based on the MSI values associated with the neighbor base stations. Numerical results show that the proposed PMHO algorithm can effectively reduce both the number of handover and the size of the neighbor-scanning set within the mobile device.
Chromatin Immunoprecipitation–on-Chip Reveals Stress-Dependent p53 Occupancy in Primary Normal Cells but Not in Established Cell Lines (2008)

The p53 tumor suppressor protein is a transcription factor that plays a key role in the cellular response to stress and cancer prevention. Upon activation, p53 regulates a large variety of genes causing cell cycle arrest, apoptosis, or senescence. We have developed a p53-focused array, which allows us to investigate, simultaneously, p53 interactions with most of its known target sequences using the chromatin immunoprecipitation (ChIP)-on-chip methodology. Applying this technique to multiple cell types under various growth conditions revealed a profound difference in p53 activity between primary cells and established cell lines. We found that, in peripheral blood mononuclear cells, p53 exists in a form that binds only a small subset of its target regions. Upon exposure to genotoxic stress, the extent of targets bound by p53 significantly increased. By contrast, in established cell lines, p53 binds to essentially all of its targets irrespective of stress and cellular fate (apoptosis or arrest). Analysis of gene expression in these established lines revealed little correlation between DNA binding and the induction of gene expression. Our results suggest that nonactivated p53 has limited binding activity, whereas upon activation it binds to essentially all its targets. Additional triggers are most likely required to activate the transcriptional program of p53.
Implementation of nationwide screening of pregnant women for HTLV-1 infection in Japan: analysis of a repeated cross-sectional study (2020)

The nationwide screening program for HTLV-1 in Japan was almost fully implemented. However, regional variations in screening tests were observed during this implementation. Thus, some incentives are needed to encourage proper implementation across all regions.
Achieving Balance of Valley Occupancy in Narrow AlAs Quantum Wells (2019)

Terahertz photoconductivity of $100~μ$m and $20~μ$m Hall bars fabricated from narrow AlAs quantum wells (QWs) of different widths is investigated in this paper. The photoresponse is dominated by collective magnetoplasmon excitations within the body of the Hall structure. We observed a radical change of magnetoplasma spectrum measured precisely for AlAs QWs of width ranging from $4$~nm up to $15$~nm. We have shown that the observed behavior is a vivid manifestation of valley transition taking place in the two-dimensional electron system. Remarkably, we show that photoresponse for AlAs QWs of width $6$~nm features two resonances, indicating simultaneous occupation of strongly anisotropic $X_{x-y}$ valleys and isotropic $X_z$ valley in the QW plane. Our results pave the way to realizing valley-selective layered heterostructures, with potential application in valleytronics.
Sustainable Regional Economic Development (2001)

(2001). Sustainable Regional Economic Development. Journal of Economic Issues: Vol. 35, Papers From The 2001 AFEE Meeting, pp. 469-476.
Daily stock market forecast from textual web data (2002)

Our aim is to predict stock markets using information contained in articles published on the Web, mostly textual articles appearing in the leading and influential financial newspapers. From those articles the daily closing values of major stock market indices in Asia, Europe and America are predicted. Textual statements contain not only the effect but also why it happened. A prediction system has been built that uses data mining techniques and sophisticated keyword tuple counting and transformation to produce periodically forecasts in stock markets. Exploiting textual information in addition to numeric time series data increases the quality of the input, hence improved predictions are expected. The forecasts are available in real-time via the Internet Web site. The system's accuracy for this difficult but also extremely challenging application is highly promising.
The Influence of some Xanthone Derivatives on the Activity of J-774A.1 Cells (2009)

The chemiluminescence of stimulated cells with phorbol myristate acetate and the production of nitric oxide after stimulation with lipopolisaccharide in the presence of the parent compounds FAA (flavone-8-acetic acid = (4-oxo-2- phenyl-4H-chromen-8-yl)acetic acid), XAA (xanthone-4-acetic acid = (9-oxo-9Hxanthen- 4-yl)acetic acid), and appropriate xanthone derivatives (1–7) was determined. Also the toxicity of the FAA, MFAA ((6-methyl-4-oxo-2-aryl-4H-chromen- 8-yl)acetic acid), XAA and 1–7 against J-774A.1 cultured cells was evaluated. Compound 5 (2-methyl-2-{[(9-oxo-9H-xanthen-2-yl)methyl]sulfanyl}- propanoic acid) was effective in inhibiting chemiluminescence of J-774A.1 cells but most of the other tested compounds stimulated the reaction. FAA and two xanthones with a methoxycarbonyl moeity slightly decreased the generation of nitric oxide at 50 μM. Most of the tested compounds (1–7) showed weak toxicity at concentration of 100 μM.