gebhart/patrepeval huggingface dataset:
Bi-state control of parametric resonance (2013)

We report a bi-state controller capable of serving along the microelectromechanical parametric resonant bifurcation point at large displacement amplitudes. The feedback states are two levels of the electrostatic-drive polarization voltage that shift the nonlinear resonance characteristics. The system is driven at a fixed frequency. The feedback states correspond to two steady-state conditions: the “on” state experiencing parametric resonance and the “off” state at zero amplitude. The states are cycled by 200 kHz pulse-width-modulation that circumvents hysteretic latch-on that occurs in an equivalent continuous-time analog feedback. The exemplary system demonstrated has 1.9 μm servo amplitude with 2 Å minimum Allan deviation.
Synthèse des réponses écrites (2000)

info:eu-repo/semantics/published
Prophecy, Policy, and the Unfolding of God’s Plan (2009)

This chapter considers survey research about white evangelicals’ motives for supporting Israel. It reports on a religious service at a charismatic church that celebrated the emigration of the Jews to Israel as hastening Christ’s return. For enormous numbers of born-again Christians, supporting the Jewish return to the Holy Land allows them to join in the unfolding of divine history. Many disavow any intention of hastening scriptural prophecy, however. The chapter discusses another way to speed the end-times: building the Third Temple in Jerusalem. It notes plots to destroy the Dome of the Rock in order to clear the Temple Mount for the construction of the Temple. And it describes the biblically prescribed need for a red heifer to purify workers who would build the Temple. The chapter concludes by questioning the charge that George W. Bush is a Christian Zionist, perhaps even a premillennial dispensationalist, and that his faith shaped his Middle East policies.
Bactericidal Capacity of Silver Nanoparticles Associated with Gantrez S-97 on Streptococcus Mutans (2010)

The addition of Gantrez 2% to silver nanoparticles does not alter its antimicrobial effect.
Early clearance of plasma EGFR mutations as a predictor of response to osimertinib and comparator EGFR-TKIs in the FLAURA trial. (2019)

9020 Background: In the Phase III FLAURA trial (NCT02296125), osimertinib, a third generation EGFR-TKI, showed superior efficacy to comparator EGFR-TKIs as first line treatment for EGFR mutation-positive (EGFRm) advanced NSCLC. In an exploratory analysis, we investigated clinical outcomes associated with detection of plasma EGFRm at 3 or 6 weeks (wks) after start of treatment. Methods: Treatment-naïve patients (pts) with EGFRm (ex19del or L858R) locally advanced or metastatic NSCLC were randomized 1:1 to receive osimertinib 80 mg once daily (QD) or comparator EGFR-TKIs (gefitinib 250 mg QD or erlotinib 150 mg QD). Plasma EGFR mutation analysis was conducted at baseline (BL), wks 3 and 6 by droplet digital PCR. Clearance was defined as undetectable levels of EGFRm in ctDNA at wks 3/6, where they were detectable at BL. Progression-free survival (PFS) was investigated based on early clearance of EGFRm. Results: In total 489/556 (88%) pts (osimertinib: 244/279; comparator: 245/277) had evaluable ctDNA at BL and wks 3/6. Of these, 342/489 (70%; osimertinib: 168/244; comparator: 174/245) had detectable BL EGFRm and were included in this analysis. See table. Conclusions: Clearance of plasma EGFRm after 3/6 wks of EGFR-TKI therapy was associated with a numerical improvement in PFS. The efficacy of osimertinib was superior to comparator EGFR-TKIs regardless of clearance status. Clinical trial information: NCT02296125. [Table: see text]
Core Loss Prediction in Large Hydropower Generators: Influence of Rotational Fields (2009)

In this paper, we discuss the accuracy of several core loss models as compared to experimental data obtained from measurements on commercial hydropower generators. Our aim in this paper is twofold. First, we emphasize the problem of total core loss prediction by comparing the core loss figures obtained by different loss prediction schemes with measured no-load losses. Second, we examine the predicted net effect of bidirectional flux, i.e., the rotational loss. We show that the average degree of rotation in the stator core, and hence the rotational loss, is closely related to the stator slot geometry.
Pulsed blue light inactivates two strains of human coronavirus (2021)

Emerging evidence suggests that blue light has the potential to inactivate viruses. Therefore, we investigated the effect of 405 nm, 410 nm, 425 nm and 450 nm pulsed blue light (PBL) on human alpha coronavirus HCoV-229 E and human beta coronavirus HCoV-OC43, using Qubit fluorometry and RT-LAMP to quantitate the amount of nucleic acid in irradiated and control samples. Like SARS-CoV-2, HCoV-229E and HCoV-OC43 are single stranded RNA viruses transmitted by air and direct contact; they have similar genomic sizes as SARS-CoV-2, and are used as surrogates for SARS-CoV-2. Irradiation was carried out either at 32.4 J cm<sup>-2</sup> using 3 mW cm<sup>-2</sup> irradiance or at 130 J cm<sup>-2</sup> using 12 mW cm<sup>-2</sup> irradiance. Results: (1) At each wavelength tested, PBL was antiviral against both coronaviruses. (2) 405 nm light gave the best result, yielding 52.3% (2.37 log<sub>10</sub>) inactivation against HCoV-OC43 (p < .0001), and a significant 1.46 log <sub>10</sub> (44%) inactivation of HCoV-229E (p < .01). HCoV-OC43, which like SARS-CoV-2 is a beta coronavirus, was more susceptible to PBL irradiation than alpha coronavirus HCoV-229E. The latter finding suggests that PBL is potentially antiviral against multiple coronavirus strains, and that, while its potency may vary from one virus to another, it seems more antiviral against beta coronaviruses, such as HCoV-OC43. (3) Further, the antiviral effect of PBL was better at a higher irradiance than a lower irradiance, and this indicates that with further refinement, a protocol capable of yielding 100% inactivation of viruses is attainable.
The evolution of virtual machine architecture (1973)

In the early 1960's two major evolutionary steps were taken with regard to computing systems architecture. These were the emergence of I/O processors and the use of multiprogramming to improve resource utilization and overall performance. As a consequence of the first step computing systems became multiprocessor configurations where nonidentical processors could have access to the common main memory of the system. The second step resulted in several computational processes sharing a single processor on a time-multiplexed basis while vying for a common pool of resources.
Clinical, histologic and serologic evaluation of patients with acute non-A-E hepatitis in north-eastern Brazil: is it an infectious disease? (2003)

Non-A-E hepatitis and acute cryptogenic hepatitis are the names given to the disease of patients with clinical hepatitis, but in whom serologic evidence of A-E hepatitis has not been found. Over a period of 8 years, we evaluated in Brazil 32 patients who fulfilled the criteria for this diagnosis in order to determine patterns of the clinical illness, laboratory parameters, or histologic features. Each patient was subjected to virologic tests to exclude A-E hepatitis and cytomegalovirus/Epstein-Barr virus infection. Drug-induced hepatitis and autoimmune disease were also excluded. Wilson's disease was excluded in young patients. The course of the disease was clinical/biochemical recovery in 3 months in 25 patients and persistent alanine aminotransferase (ALT) elevation in 7 patients. Three of these had chronic hepatitis, and one had severe fibrosis on liver biopsy. During the acute illness, mean peak ALT was 1267 IU/L, bilirubin was 4.0 mg/dL, and ferritin was 1393 IU/mL. GB virus type C (GBV-C) was found in six patients, and TT virus (TTV) in five patients. We conclude that, in Brazil, non-A-E hepatitis probably originates from still unidentified viruses. The course of the disease and the histologic patterns are similar to those recorded for known viruses. Continuous survey for the specific etiologic agents is needed.
New Collision Force Suppression Mechanism and Base Control of Human-Friendly Robot (2018)

This paper describes a human-friendly robot capable of securing human safety in human-robot collisions. The upper body of the robot has 11 DOFs, including 3 DOFs in the waist, 2 DOFs in each shoulder, 1 DOF in each elbow and 1 DOF in each hand. The upper body is mounted on the base with four omnidirectional wheels. A new light-weight collision force suppression mechanism that is able to operate with very little Backlash was developed and was installed at the elbow of the human-friendly robot. The suppression mechanism consists a drum, a clutch gear, two release air Bag, two stopper linings, and four compression springs. Also, a base control method to secure human safety is discussed. Through collision experiments, the effectiveness of the collision force suppression mechanism and control method is verified.
Wide Field-of-View Lensless Imaging of Caenorhabditis Elegans On a Chip (2010)

Wide field-of-view lensfree on-chip imaging of C. Elegans samples is demonstrated using incoherent lensless in-line holography. Digital reconstruction of these lensless holograms rapidly creates the C. Elegans images over a field-of-view of &gt;24mm2.
Systematically Defining Single-Gene Determinants of Response to Neoadjuvant Chemotherapy Reveals Specific Biomarkers (2014)

Systematic computational approaches can define key genes that will be able to predict the response to chemotherapy across multiple treatment modalities yielding a small collection of biomarkers that can be readily deployed by IHC analyses.
Practical Applications of Thermophysical Property Measurements in Oil Shale Technology (1981)

Abstract The dependence of thermophysical properties such as thermal conductivity, thermal diffusivity, specific heat, and dielectric constant on organic content is discussed for oil shales of the Green River Formation. The applicability of thermophysical measurements for assaying and retort diagnostic purposes is also discussed in the light of methods that are currently in use in oil shale science and technology.
LiPF[sub 3](CF[sub 2]CF[sub 3])[sub 3]: A Salt for Rechargeable Lithium Ion Batteries (2003)

from Merck KGaA (LiFAP) was tested as a new electrolyte for Li-ion batteries that can replace the commonly used The latter salt is known to be unstable, to decompose thermally to LiF and and to readily undergo hydrolysis with protic species to form HF contamination in solutions. The latter contamination may have a detrimental impact on the performance of both anodes and cathodes for Li-ion batteries. Solutions comprising LiFAP, and (LiBETI) in mixtures of ethylene, dimethyl, and diethyl carbonates were tested with composite graphite and electrodes. The tools for this study included voltammetry (fast and slow scan rates), chronopotentiometry, impedance spectroscopy, Fourier transform infrared, and X-ray and photoelectron spectroscopies. It was found that LiFAP is superior to as an electrolyte for both graphite anodes and cathodes. This should be attributed to the different surface chemistry developed on these electrodes when is replaced by LiFAP. An important impact of such a replacement is probably the absence of possible pronounced HF contamination in LiFAP solutions. © 2003 The Electrochemical Society. All rights reserved.
Protective Tumor Immunity Induced by Potassium Chloride Extracts of Guinea Pig Hepatomas (1975)

Tumor-specific antigens of cells of the diethylnitrosamine-induced hepatomas in strain-2 guinea pigs were extracted with 3 M KCl. Immunization of normal animals with the extracted tumor antigens in adjuvant protected them against a subsequent challenge with viable tumor cells. Extracted tumor-specific antigens were less effective immunogens than viable tumor cells for both of two antigenically distinct lines.
Primal Decomposition-Based Method for Weighted Sum-Rate Maximization in Downlink OFDMA Systems (2010)

We consider the weighted sum-rate maximization problem in downlink Orthogonal Frequency Division Multiple Access (OFDMA) systems. Motivated by the increasing popularity of OFDMA in future wireless technologies, a low complexity suboptimal resource allocation algorithm is obtained for joint optimization of multiuser subcarrier assignment and power allocation. The algorithm is based on an approximated primal decomposition-based method, which is inspired from exact primal decomposition techniques. The original nonconvex optimization problem is divided into two subproblems which can be solved independently. Numerical results are provided to compare the performance of the proposed algorithm to Lagrange relaxation based suboptimal methods as well as to optimal exhaustive search-based method. Despite its reduced computational complexity, the proposed algorithm provides close-to-optimal performance.
Characterizing Sulfur in TEM and STEM, with Applications to Lithium Sulfur Batteries (2014)

The lithium sulfur (Li-S) battery is a promising technology with the potential to provide greater energy density at lower cost than current lithium ion batteries. One of the main challenges to improving the performance of Li-S batteries is the dissolution and loss of sulfur to the electrolyte as the battery is cycled Recently much effort has focused on nanostructured electrodes that could sequester the sulfur and prevent its loss during battery operation. Analyzing the distribution of sulfur in these electrodes is critical for creating durable Li-S batteries with high energy density.
[Photomedicine in gynecology]. (1998)

In ancient years, knowledge about healing capacity of extracts from plants together with sunshine became evident in medicine. In our days second generation photosensitizers (they stand for plant extracts) and laser light (stands for sunshine) are ready for use in the clinic. Photomedicine recently became a selfstanding clinical area composed of photodynamic diagnosis (PDD) and photodynamic therapy (PDT) as its subdisciplines. Clinical application of photomedicine in gynaecology has been carefully prepared. By a number of experiments using in vitro and in vivo techniques a basis was developed to make possible clinical photomedical applications in gynaecology. In PDD 5-aminolevulinic acid, a stimulator for the production of cellular protoporphyrin IX, was used for the detection of tumour lesions of microscopical dimensions. Another approach in PDD called Frequency Domain Photon Migration technology makes it possible to quantify amounts of hem, water and oxygen in a given (tumour) tissue area. They are different from normal breast tissue. In PDT besides new technological components (diode lasers, light diffusers) there is specific need for new photosensitizers whose wavelength of activation is in the area of near infrared, allowing a better tissue penetration. Very recently, research results indicated that PDT does not create resistance against its own and suggest that this procedure can be used successfully even after radio- and/or chemotherapy. PDT of non-neoplastic but pathological cell proliferation such as endometriosis is very promising. One goal in gynaecology will be a reduction of the number of hysterectomies surgically performed by this minimally invasive approach.
A feature-based recognition scheme for traffic scenes (2002)

This paper describes a method for the interpretation of traffic scenes based on the detection and recognition of those objects, or classes of objects which are typically found in an urban scene. Since generic model-based recognition schemes are unsuitable for the analysis of traffic scenes and result in very poor performances, each of the different classes of objects which we expect to find in a typical scene is identified according to some selected features. After identifying the object, its main parameters are computed and, when needed, the object is further classified. The classes of objects we have considered included the roadbed, vehicles, buildings, trees, crosswalks and road signs. The method described here has been successfully tested on a wide set of images of traffic scenes and provided a general-purpose reconstruction of the whole traffic scene as viewed by the driver.
Parallel computing and the OS (2015)

Frans Kaashoek's talk divided research on parallelism in operating systems in 4 periods. Around the first SOSP, the OS community introduced foundational ideas for parallel programming, covering three types of parallelism in operating systems: user-generated parallelism, I/O parallelism, and processor parallelism. With the advent of distributed computing, the OS community focused its attention to make it easy for server programmers to exploit parallelism, in particular I/O parallelism. With the arrival of commodity small-scale multiprocessors, the OS community "rediscovered" the importance of processor parallelism and contributed techniques to scale operating systems to large number of processors. These techniques found their way in today's main-stream operating systems because today's processors contain by default several cores. Because software must be parallel to exploit multicore processors, the OS community is going through a "rebirth" of research in parallel computing.
The impact of a vegetarian diet on chronic kidney disease (CKD) progression – a systematic review (2023)

The findings collected in this systematic review suggest that a vegetarian diet improves renal filtration function in CKD patients. Therefore, it seems essential to conduct further research involving the impact of the diet on the progression of CKD.
Cell Lineage Reconstruction of Early Zebrafish Embryos Using Label-Free Nonlinear Microscopy (2010)

Quantifying cell behaviors in animal early embryogenesis remains a challenging issue requiring in toto imaging and automated image analysis. We designed a framework for imaging and reconstructing unstained whole zebrafish embryos for their first 10 cell division cycles and report measurements along the cell lineage with micrometer spatial resolution and minute temporal accuracy. Point-scanning multiphoton excitation optimized to preferentially probe the innermost regions of the embryo provided intrinsic signals highlighting all mitotic spindles and cell boundaries. Automated image analysis revealed the phenomenology of cell proliferation. Blastomeres continuously drift out of synchrony. After the 32-cell stage, the cell cycle lengthens according to cell radial position, leading to apparent division waves. Progressive amplification of this process is the rule, contrasting with classical descriptions of abrupt changes in the system dynamics.
Effects of enalapril on endothelin-1 and growth factor gene expression in diabetic rat glomeruli. (1994)

We have previously reported that the mRNA levels of endothelin (ET-1), tumor necrosis factor-alpha), (TNF-alpha), platelet-derived growth factor (PDGF)-B chain, transforming growth factor (TGF-beta), and basic fibroblast growth factor (bFGF) all increased with age in diabetic rat glomeruli. We have now assessed the effect of the angiotensin-converting enzyme inhibitor enalapril on the expression of the ET-1, TNF-alpha, PDGF-B, TGF-beta, and bFGF genes in 24-week-old rat glomeruli after streptozotocin injection. Animals were divided into controls, enalapril-treated diabetic rats, and untreated diabetic rats. Treatment continued for 24 weeks. Enalapril reduced both creatinine clearance (p < 0.001) and urinary protein excretion (p < 0.01) in diabetic rats. Enalapril produced a nonsignificant 15 mm Hg reduction in blood pressure in diabetic rats. Enalapril also attenuated the increases in ET-1 mRNA levels observed in the glomeruli of diabetic rats (0.5-fold compared with untreated diabetic rats at 24 weeks [p < 0.01]) but had no effect on increased mRNA levels of TNF-alpha, PDGF-B, TGF-beta, and bFGF. These findings suggest that enalapril therapy may be effective in reducing ET-1 mRNA expression in the glomeruli of diabetic nephropathy.
Conflict of Interest Policies and Disclosure Requirements Among European Society of Cardiology National Cardiovascular Journals (2012)

Disclosure of potential conflicts of interest (COI) is used by biomedical journals to guarantee credibility and transparency of the scientific process. COI disclosure, however, is not systematically nor consistently dealt with by journals. Recent joint editorial efforts paved the way towards the implementation of uniform vehicles for COI disclosure. This paper provides a comprehensive editorial perspective on classical COI-related issues. New insights into current COI policies and practices among European Society of Cardiology national cardiovascular journals, as derived from a cross-sectional survey using a standardised questionnaire, are discussed.
InGaAsP/InP planar buried heterostructure lasers with semi-insulating InP current blocking layers grown by MOCVD (1987)

InGaAsP/InP planar buried heterostructure (BH) lasers with semi-insulating current blocking layers have been realized using LPE and MOCVD hybrid growth. The planar structure has been obtained by developing the selective embedding growth in MOCVD. Low threshold current of 17 mA and high efficiency of 42 percent have been attained with the BH lasers. Small-signal modulation bandwidth of 10 GHz has also been achieved.
Anal sphincter reconstruction with a pudendal nerve anastomosis following abdominoperineal resection (1997)

This method is a promising procedure for reconstructing the anal sphincter.
The YΦ Motif Defines the Structure-Activity Relationships of Human 20S Proteasome Activators (2021)

The 20S proteasome (20S) facilitates turnover of most eukaryotic proteins. Substrate entry into the 20S first requires opening of gating loops through binding of HbYX motifs that are present at the C-termini of certain proteasome activators (PAs). The HbYX motif has been predominantly characterized in the archaeal 20S, whereas little is known about the sequence preferences of the human 20S ( h 20S). Here, we synthesized and screened ∼120 HbYX-like peptides, revealing unexpected differences from the archaeal system and defining the h 20S recognition sequence as the Y-F/Y (YΦ) motif. To gain further insight, we created a functional chimera of the optimized sequence, NLSYYT, fused to the model activator, PA26 E102A .A cryo-EM structure of PA26 E102A - h 20S identified key interactions, including non-canonical contacts and gate-opening mechanisms. Finally, we demonstrated that the YΦ sequence preferences are tuned by valency, allowing multivalent PAs to sample greater sequence space. These results expand the model for termini-mediated gating and provide a template for the design of h 20S activators.
Photoemission Experiments for Charge Characteristics of Individual Dust Grains (2001)

Photoemission experiments with UV radiation have been performed to investigate the microphysics and charge characteristics of individual isolated dust grains of various compositions and sizes by using the electrodynamic balance facility at NASA Marshall Space Flight Center. Dust particles of 2–10 µm diameter are levitated in a vacuum chamber at pressures ∼10-5 torr and exposed to a collimated beam of UV radiation in the 120–200 nm spectral range from a deuterium lamp source with a MgF2 window. A monochromator is used to select the UV wavelength with a spectral resolution of 8 nm. The electrodynamic facility permits measurements of the charge and diameters of particles of known composition, and monitoring of photoemission rates with the incident UV radiation. Experiments have been conducted on test particles of silica and polystyrene to determine the photoelectric yields and surface equilibrium potentials when exposed to UV radiation. A brief description of an experimental procedure for photoemission studies is given and some preliminary laboratory measurements of the photoelectric yields of individual dust particles are presented.