gebhart/patrepeval huggingface dataset:
Thiosocius teredinicola gen. nov., sp. nov., a sulfur-oxidizing chemolithoautotrophic endosymbiont cultivated from the gills of the giant shipworm, Kuphus polythalamius (2018)

A chemolithoautotrophic sulfur-oxidizing, diazotrophic, facultatively heterotrophic, endosymbiotic bacterium, designated as strain 2141T, was isolated from the gills of the giant shipworm Kuphus polythalamius (Teredinidae: Bivalvia). Based on its 16S rRNA sequence, the endosymbiont falls within a clade that includes the as-yet-uncultivated thioautotrophic symbionts of a marine ciliate and hydrothermal vent gastropods, uncultivated marine sediment bacteria, and a free-living sulfur-oxidizing bacterium ODIII6, all of which belong to the Gammaproteobacteria. The endosymbiont is Gram-negative, rod-shaped and has a single polar flagellum when grown in culture. This bacterium can be grown chemolithoautotrophically on a chemically defined medium supplemented with either hydrogen sulfide, thiosulfate, tetrathionate or elemental sulfur. The closed-circular genome has a DNA G+C content of 60.1 mol% and is 4.79 Mbp in size with a large nitrogenase cluster spanning nearly 40 kbp. The diazotrophic capability was confirmed by growing the strain on chemolithoautotrophic thiosulfate-based medium without a combined source of fixed nitrogen. The bacterium is also capable of heterotrophic growth on organic acids such as acetate and propionate. The pH, temperature and salinity optima for chemolithoautotrophic growth on thiosulfate were found to be 8.5, 34 °C and 0.2 M NaCl, respectively. To our knowledge, this is the first report of pure culture of a thioautotrophic animal symbiont. The type strain of Thiosocius teredinicola is PMS-2141T.STBD.0c.01a<sup>T</sup> (=DSM 108030<sup>T</sup>).
A Pilot Study on Using Derivatives of Photoplethysmographic Signals as a Biometric Identifier (2007)

Photoplethysmographic (PPG) signals are easy to obtain with low cost, which enhances its potential to server as biometric identification mechanism for various applications. This paper examines two important issues in applying derivatives of PPG signals as discriminants to identify and verify subjects: consistency within an individual subject and discriminability between different subjects. The experimental results demonstrate that, by employing statistical tools, derivatives can precisely describe the features of an individual's PPG signal and be used as bio-measures for identification purposes.
EXPLORING THE IIEF-5: HOW BOTHERED ARE MEN WITH SEVERE ED BY THEIR CONDITION? (2009)

You have accessJournal of Urology1 Apr 2009EXPLORING THE IIEF-5: HOW BOTHERED ARE MEN WITH SEVERE ED BY THEIR CONDITION? Adam W Levinson, Nicholas T Ward, Phillip M Pierorazio, Lynda Z Mettee, Li-Ming Su, and Christian P Pavlovich Adam W LevinsonAdam W Levinson More articles by this author , Nicholas T WardNicholas T Ward More articles by this author , Phillip M PierorazioPhillip M Pierorazio More articles by this author , Lynda Z MetteeLynda Z Mettee More articles by this author , Li-Ming SuLi-Ming Su More articles by this author , and Christian P PavlovichChristian P Pavlovich More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(09)61054-5AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "EXPLORING THE IIEF-5: HOW BOTHERED ARE MEN WITH SEVERE ED BY THEIR CONDITION?." The Journal of Urology, 181(4S), p. 373 © 2009 by American Urological AssociationFiguresReferencesRelatedDetails Volume 181Issue 4SApril 2009Page: 373 Advertisement Copyright & Permissions© 2009 by American Urological AssociationMetricsAuthor Information Adam W Levinson More articles by this author Nicholas T Ward More articles by this author Phillip M Pierorazio More articles by this author Lynda Z Mettee More articles by this author Li-Ming Su More articles by this author Christian P Pavlovich More articles by this author Expand All Advertisement PDF downloadLoading ...
Why Is the Standardization of Prothrombin Time a Problem? (2000)

The standardization of prothrombin time (PT) has been a problem for more than 50 years; by applying the methods to the same clinical material the analysis may explain why. The initial standardization by 2--3 times normal clotting time by Quick's PT assay did not standardize presently used PT assays. The ratio method accepted by the WHO in 1977 was not satisfactory because the intercept was neglected. The revised ratio method (WHO 1983) recommended calibration between log clotting times of normal and abnormal plasmas and a simplified conversion into ratios. However, by including a high proportion of normal plasmas (up to 1/3 of abnormal) an erroneous calibration material was introduced; the conversion from clotting times into ratios was also more complex than predicted. The international sensitivity index, which is based on the simplified method, produced international normalized ratios (INR) that were not more standardized than not corrected ratios. Not corrected coagulation activities showed poor standardization due to the different sensitivity of assays for the protein induced by vitamin K absence (Pivka) inhibitor. The corresponding therapeutic ranges of INR and coagulation activities covered 70 and 10--20% of their scales, respectively. Standardization by Pivka-corrected coagulation activities against an international reference assay may be the preferable method.
Mechanisms of Solute Transport in Extracorporeal Therapies (2005)

Diffusion and convection are the main mechanisms involved in the membrane separation processes occurring in extracorporeal hemodialysis. Operational parameters should be optimized in hollow fiber hemodialyzers to achieve the maximal efficiency. The nature of blood which is a non Newtonian fluid, requires specific attention in the design of dialyzers to ensure that the blood compartment operates properly. Similar attention must be placed in the design of the dialysate compartment to ensure a homogeneous distribution of the fluid and to prevent blood to dialysate flow mismatch. Finally, the membrane represents the third component of the hemodialyzer. Membrane performance depends on the used biomaterial, its biocompatibility, the thickness, the hydrophilic-hydrophobic mixture, the hydraulic permeability and the number and diameter of the pores. In this setting, diffusion and convection tend to reciprocally interfere, producing a final result that depends on the prevalence of one or the other mechanism for every specific solute.
Enhanced decay instability and mode conversion to a strongly-damped nonlinear wave (1994)

When one of the waves in mode conversion or in decay instability is weakly nonlinear, the phase mismatch produced by spatial nonuniformity can be balanced by the nonlinear shift of wavenumber. This produces great enhancement of conversion and unlimited convective growth in the instability.
CUSP9* treatment protocol for recurrent glioblastoma: aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline augmenting continuous low dose temozolomide (2014)

CUSP9 treatment protocol for recurrent glioblastoma was published one year ago. We now present a slight modification, designated CUSP9*. CUSP9* drugs--aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, sertraline, ritonavir, are all widely approved by regulatory authorities, marketed for non-cancer indications. Each drug inhibits one or more important growth-enhancing pathways used by glioblastoma. By blocking survival paths, the aim is to render temozolomide, the current standard cytotoxic drug used in primary glioblastoma treatment, more effective. Although esthetically unpleasing to use so many drugs at once, the closely similar drugs of the original CUSP9 used together have been well-tolerated when given on a compassionate-use basis in the cases that have come to our attention so far. We expect similarly good tolerability for CUSP9*. The combined action of this suite of drugs blocks signaling at, or the activity of, AKT phosphorylation, aldehyde dehydrogenase, angiotensin converting enzyme, carbonic anhydrase -2,- 9, -12, cyclooxygenase-1 and -2, cathepsin B, Hedgehog, interleukin-6, 5-lipoxygenase, matrix metalloproteinase -2 and -9, mammalian target of rapamycin, neurokinin-1, p-gp efflux pump, thioredoxin reductase, tissue factor, 20 kDa translationally controlled tumor protein, and vascular endothelial growth factor. We believe that given the current prognosis after a glioblastoma has recurred, a trial of CUSP9* is warranted.
The Electrochemistry of Colloidal Semiconductor Particles: Experiments on and (1984)

Results are presented for the dark electrochemistry and photoelectrochemistry of and colloidal particles studied with the optical rotating disk electrode (ORDE). The electron‐transfer reactions between the particles and the electrode are found to be irreversible. However, in agreement with theoretical predictions, the kinetics obey both the Tafel and Levich relations. Several hundred electrons may be transferred on each encounter between a particle and the ORDE. Added halide ions are shown to be good scavengers for photogenerated holes. Results for the quantum efficiencies for the photogeneration of majority carriers are reported.
Synthesis and Binding Affinities of Novel Re-Containing 7α-Substituted Estradiol Complexes:  Models for Breast Cancer Imaging Agents (1999)

The diagnosis and staging of breast cancer could be improved by the development of imaging radiopharmaceuticals that provide a noninvasive determination of the estrogen receptor status in the tumor cells. Toward this goal, we have synthesized a number of novel Re-containing 7alpha-substituted estradiol complexes. The introduction of the 7alpha side chain involves the alkylation of tetrahydropyranyloxy-protected 6-keto estradiol. The methods used to introduce the rhenium metal involve "3 + 1" and "4 + 1" mixed ligand complexes (2a-c and 5, respectively), tricarbonyl dithioether complexes (3), and the cyclopentadienyltricarbonylmetal organometallic system (4ab, 6, 7). These complexes showed binding affinities for the estrogen receptor (as high as 45% for the "3 + 1" complex 2c) when compared to the native ligand estradiol. The polarity of some complexes (4ab) was modified to improve biodistribution properties by introducing (poly)ether linkages into the 7alpha side chain (6, 7). These complexes provide a further refinement of our understanding of ligand structure-binding affinity correlations for the estrogen receptor, and they furnish the synthetic groundwork for the synthesis of the analogous Tc-99m complexes for evaluation as breast tumor imaging agents.
LRb-STAT3 Signaling Is Required for the Neuroendocrine Regulation of Energy Expenditure by Leptin (2004)

Secretion of leptin from adipose tissue communicates body energy status to the neuroendocrine system by activating the long form of the leptin receptor (LRb). Lack of leptin or LRb (as in db/db mice) results in obesity that stems from the combined effects of hyperphagia and decreased energy expenditure. We have previously generated mice in which LRb is replaced with a mutant LRb (LRbS1138) that specifically disrupts LRb-->STAT3 (signal transducer and activator of transcription-3) signaling; mice homozygous for this mutant (s/s) display increased feeding and are obese. We have now examined energy expenditure in s/s and db/db mice. Consistent with the increased lean body mass of s/s animals, locomotor activity and acute cold tolerance (partly a measure of shivering thermogenesis) in s/s mice were modestly but significantly improved compared with db/db mice, although they were decreased compared with wild-type mice. Total and resting metabolic rates were similarly depressed in s/s and db/db mice, however. Indeed, s/s and db/db mice display similar reductions in thyroid function and brown adipose tissue expression of uncoupling protein-1, which is regulated by sympathetic nervous system (SNS) tone. Thus, the LRb-->STAT3 signal is central to both the control of energy expenditure by leptin and the neuroendocrine regulation of the SNS and the thyroid axis.
Bismuth Alkoxides. The First Structurally-Characterized Bismuth−Transition Metal Heterobimetallic Alkoxide:  [BiCl3OV(OC2H4OCH3)3]2 (1996)

The reaction of BiCl3 and VO(OiPr)3 in 2-methoxyethanol resulted in the formation of the first bismuth-transition metal bimetallic alkoxide, [BiCl3(μ-O)(μ-OC2H4OCH3)2(OC2H4OCH3)V]2. The vanadium atom is in an unusual distorted octahedral coordination environment, while the coordination around the bismuth is best described as an octrahedron capped by a long bonded interaction with an oxygen atom. There does not appear to be a stereochemically-active lone pair present on the bismuth atom.
Bioactive Sesterterpenoids from a Korean Sponge Monanchora sp. (2013)

Chemical investigation of a Korean marine sponge, Monanchora sp., yielded nine new sesterterpenoids (1-9) along with phorbaketals A-C (10-12). The planar structures were established on the basis of NMR and MS analysis, and the absolute configurations of 1-9 were defined using the modified Mosher's method and CD spectroscopic data analysis. Compounds 1-8, designated as phorbaketals D-K, possess a spiroketal-modified benzopyran moiety such as phorbaketal A, and their structural variations are due to oxidation and/or reduction of the tricyclic core or the side chain. Compound 9, designated as phorbin A, has a monocyclic structure and is proposed to be a possible biogenetic precursor of the phorbaketals. Compounds 1-9 were evaluated for cytotoxicity against four human cancer cell lines (A498, ACHN, MIA-paca, and PANC-1), and a few of them were found to exhibit cytotoxic activity.
Wind-induced plant motion immediately increases cytosolic calcium. (1992)

Wind is one of the most unusual and more dramatic of the environmental signals to modify plant development. Wind-stimulated crops are also known to experience considerable reductions in growth and subsequent yield. There is at present no experimental data to suggest how wind signals are perceived and transduced by plant cells. We have genetically transformed Nicotiana plumbaginifolia to express aequorin and thus produced luminous plants that directly report cytosolic calcium by emitting blue light. With these plants we have found wind stimulation to cause immediate increases in cytosolic calcium and our evidence, based on the use of specific inhibitors, suggests that this calcium is mobilized from organelle sources. Our data further suggest that wind-induced movement of tissues, by mechanically stimulating and stressing constituent plant cells, is responsible for the immediate elevation of cytosolic calcium; increases occur only when the plant tissue is actually in motion. Repeated wind stimulation renders the cells refractory to further calcium signaling but responsiveness is rapidly recovered when stimulation is subsequently diminished. Our data suggest that mechanoperception in plant cells may possibly be transduced through intracellular calcium. Since mechanoperception and transduction are considered crucial to plant morphogenesis, our observations suggest that calcium could be central in the control and generation of plant form.
The management of paediatric burns with Burns and Wounds ointment and burdock leaves: a case series (2020)

Managing burn wounds with B&W ointment and burdock leaves should be considered as an additional option for wound care in select cases. However, the efficacy of this therapy is limited and standard-of-care modern medical burn treatments should remain an option for these patients. It is critically important to build a mutually respectful relationship with Amish patients' community leaders, as this allows open communication and collaboration in patient care and increases the likelihood that Amish guardians will bring their children to a hospital when necessary.
Fine-Tuning of Luminescence through Changes in Au–S Bond Lengths as a Function of Temperature or Solvent (2019)

The luminescent properties of gold(I)-sulfur compounds have received much attention for their potential applications in the sensing field. The molecular level regulation of luminescence remains a challenge. It is critical to unravel the relationship between the luminescence and the structure. Herein we report a binuclear complex [Au<sub>2</sub>(dppaptc)<sub>2</sub>]Cl<sub>2</sub> (1, dppaptc = N,N-bis(diphenylphosphanylmethyl)-amino-4-phenyl-thiocarbamide), which exhibits variations at Au-S bond lengths as a function of temperature or solvent. X-ray analysis reveals a linear decrease from 2.900(3) to 2.745(15) Å upon cooling 1·2CHCl<sub>3</sub> from 300 to 80 K combined with a linear correlation with its luminescence intensity at 475 nm, which was confirmed by TD-DFT calculations. Compound 1, if solvated with H<sub>2</sub>O and alcohol, possesses the shorter Au-S bonds and enhanced luminescence. The close relationship between luminescence intensity and Au-S length serves as a complement to existing luminescent gold(I)-sulfur systems and provides some insight into understanding the thermochromism and solvatochromism of the gold(I)-sulfur compounds.
Advanced auto-tuning implementation for DC brushless servo motor drive system with learning algorithm-based fuzzy reasoning scheme (2002)

In this paper, the authors describe an advanced control method which incorporates an advanced system of auto-tuning implementation for AC servo system fuzzy reasoning logic with automatically-produced learning control functions. This method has three unique features: (i) it is not necessary to input the fuzzy rules to the AC servo system before starting auto-tuning operation; thus, the fuzzy rules can be automatically produced in the learning process; (ii) any knowledge of system parameter tuning techniques are not required; (iii) and high speed response and robustness can be derived from a method to estimate load parameters. The effectivenesses and feasibility of this method are practically confirmed through experimental results.
Instructions for Authors (2011)

The paper contains instructions for authors of articles for Acta IMEKO. It can be used as template for new submissions. Authors are encouraged to follow the instructions as described in this template file to produce their manuscript. This abstract should be composed in a way suitable for publication in the abstract section of electronic journals, and should state concisely what it is written in the paper. Important items are the aim of the research, the basic method and the major achievement (also numerically, when applicable). The length should not exceed 200 words.
Role of Agrobacterium VirD2 protein and plant histone H2A in T -DNA integration (1999)

Agrobacterium tumefaciens is a soil borne phytopathogen that causes crown gall tumors on plants. The process of tumor formation involves the transfer and integration of a specific DNA segment (T-DNA) from the bacterium into the plant chromosome. VirD2 is an Agrobacterium protein involved in T-DNA processing and transfer into plants. VirD2 protein covalently attaches to the T-DNA and enters into the plant cell. A C-terminal region of VirD2 called ω is involved in T-DNA integration but not T-DNA transfer. A bacterium containing a particular VirD2 ω mutation will transiently transform cells but tumors will not result. My experiments investigated the role of this ω region in T-DNA integration into the plant chromosome. I used an ω mutant Agrobacterium strain and showed that, unlike the situation with the wild-type bacterium, with this particular mutant there was little T-DNA integrated into the plant chromosome. Plant factors are postulated to be involved in T-DNA transfer and integration. To isolate plant genes that are involved in T-DNA transfer and integration, I identified several Arabidopsis thaliana T-DNA tagged mutants that are deficient in forming crown gall tumors after infection with Agrobacterium. In one of the mutants, I identified a disrupted gene that is involved in the tumorigenesis deficiency phenotype. The mutant gene encodes histone H2A. Complementation analysis indicates that histone H2A is involved in T-DNA transformation, most likely in the T-DNA integration step. I characterized the histone H2A genes in Arabidopsis . There are at least six variants of Arabidopsis histone H2A genes. During the process of complementation I discovered that germ-line transformation of Arabidopsis can bypass some of the steps involved in conventional Agrobacterium root transformation. Using different avirulent Agrobacterium mutants and Arabidopsis ecotypes and/or mutants that are resistant to Agrobacterium root transformation, I showed that germ-line transformation required Agrobacterium vir genes but not several plant genes required for Agrobacterium binding to or T-DNA integration in root tissue. Finally, I developed a potential new strategy to control crown gall disease. By using Arabidopsis as a model plant, I expressed Agrobacterium VirD2 protein in Arabidopsis and showed that transgenic plants expressing VirD2 protein are resistant to Agrobacterium root transformation.
A Unified Approach Towards Green Resource Allocation in Relay-Assisted Multiuser Networks (2017)

The rapid growth in energy consumption due to strong demands of wireless multimedia services, has become a major concern from an environmental perspective. In this paper, we investigate a novel energy-efficient resource allocation scheme for relay-assisted multiuser networks to maximize the energy efficiency (EE) of the network by jointly optimizing the subcarrier pairing permutation formed in one-to-many/many-to-one manner, subcarrier allocation, as well as the power allocation all together. By analyzing the properties of the complex mixed-integer nonlinear programming problem, which is generally very difficult to solve in its original form, we transform the problem into an equivalent convex problem by relaxing the integer variables using the concept of subcarrier time sharing, and by applying a successive convex approximation approach. Based on the dual decomposition method, we derive an optimal solution to the joint optimization problem. Numerical results are provided to validate the theoretical findings and to demonstrate the effectiveness of the proposed algorithms.
Nous avons testé pour vous... les sécateurs électriques (2006)

La taille reste une operation manuelle et traumatisante si l'on en iuge par la progression tres spectaculaire depuis 1995 (+ 500 % (*)) du nombre des troubles musculo-squelettiques chez les praticiens de la vigne, essentiellement dus a la taille non assistee. Les campagnes de taille, meme si elles s'allongent de plus en plus, constituent neanmoins une periode d'activite intense mettant a mal les organismes... Face a ces problemes, le secateur manuel, encore majoritaire, a beaucoup evolue sur le plan ergonomique. Il laisse cependant peu a peu la place au secateur electrique qui devient incontournable. Cet article a pour but de decrire et analyser le comportement des secateurs electriques de derniere generation apparus recemment sur le marche que nous avons teste sur notre domaine de Plumecoq a Chouilly.
-1.1V to +1.1V 3:1 Power Switch Architecture for Controlling Body Bias of SRAM Array in 28nm UTBB CMOS FDSOI (2016)

Temperature dependent body bias modulation of array reduces SRAM V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">MIN</sub> thereby reducing overall dynamic power. Fully Depleted Silicon On Insulator (FDSOI) technology offers single P-well SRAM bit cell that can be biased to positive voltages upto +1.1V to boost write-ability at cold temperatures and upto-1.1V to boost stability at hot temperatures. In this paper, we present the architecture and design of a 3:1 body bias power switch that can transmit positive, negative and zero voltage depending on the input from an on-chip temperature sensor. All the devices operate within their safe operating area (SOA) ensuring reliability. The implementation was done using extended gate devices supporting 1.8V operation in 28nm planar Ultra-Thin Box and Body, FDSOI CMOS (UTBB FDSOI) technology.