gebhart/patrepeval huggingface dataset:
Balancing photosynthetic light‐harvesting and light‐utilization capacities in potato leaf tissue during acclimation to different growth temperatures (1995)

We investigated the effect of temperature during growth and development on the relationship between light-harvesting capacity, indicated by chlorophyll concentration, and light-utilization potential, indicated by light- and bicarbonate-saturated photosynthetic oxygen evolution, in Solanum tuberosum L. cv. Norland. Clonal plantlets were transplanted and grown at 20 degrees C for 2 weeks before transfer to 12, 16, 20, 24 and 28 degrees C for 6 weeks. After 4 weeks of the temperature treatments, leaf tissue fresh weights per area were one-third higher in plants grown at 12 degrees C vs those grown at 28 degrees C. Conversely, chlorophyll content per area in tissue grown at 12 degrees C was less than one-half of that of tissue grown at 28 degrees C at 4 weeks. Photosynthetic capacity measured at a common temperature of 20 degrees C and expressed on a chlorophyll basis was inversely proportional to growth temperature. Leaf tissue from plants grown at 12 degrees C for 4 weeks had photosynthetic rates that were 3-fold higher on a chlorophyll basis than comparable tissue from plants grown at 28 degrees C. These results suggest that the relationship between light-harvesting capacity and light-utilization potential varies 3-fold in response to the growth temperatures examined. The role of this response in avoidance of photoinhibition is discussed.
A Brief Discussion on Capacitance Characteristics of Transformer with Amorphous Alloy Core (2001)

The capacitance characteristics of the transformer with amorphous alloy core, the structural differences between the transformer with amorphous alloy core and the traditional distribution transformer are introduced briefly. The influence of the main capacitance in transformer on insulating test is analyzed.
Indian herbal remedies for diabetes as a cause of lead poisoning (1994)

Herbal remedies from the Indian subcontinent have been found to have high concentrations of heavy metals and unsupervised treatment may result in toxicity. We report the case of an Indian patient with hepatitis who was found to have lead poisoning where the source was traced to ethnic remedies he had been taking for diabetes.
Optical contrast and laser-induced phase transition in GeCu2Te3 thin film (2013)

Fast crystallization and low power amorphization are essential to achieve rapid data recording and low power consumption in phase-change memory. This work investigated the laser-induced phase transition behaviors of GeCu2Te3 film based on the reflectance of amorphous and crystalline states. The GeCu2Te3 film showed a reflectance decrease upon crystallization, which was the opposite behavior in Ge2Sb2Te5 film. The crystallization starting time of the as-deposited GeCu2Te3 film was as fast as that of the as-deposited Ge2Sb2Te5 film. Furthermore, the GeCu2Te3 crystalline film was found to be reamorphized by laser irradiation at lower power and shorter pulse width than the Ge2Sb2Te5.
Amide chemical exchange saturation transfer at 7 T: a possible biomarker for detecting early response to neoadjuvant chemotherapy in breast cancer patients (2018)

Registration number, NL49333.041.14/ NTR4980 . Registered on 16 October 2014.
From Microprocessors to Nanostores: Rethinking System Building Blocks for the Data-Centric Era (2010)

The confluence of emerging technologies and new data-centric workloads offers a unique opportunity to rethink traditional system architectures and memory hierarchies in future designs.
Targeting the Meningeal Compartment to Resolve Chemobrain and Neuropathy via Nasal Delivery of Functionalized Mitochondria (2022)

Cognitive deficits (chemobrain) and peripheral neuropathy occur in ∼75% of patients treated for cancer with chemotherapy and persist long-term in >30% of survivors. Without preventive or curative interventions and with increasing survivorship rates, the population debilitated by these neurotoxicities is rising. Platinum-based chemotherapeutics, including cisplatin, induce neuronal mitochondrial defects leading to chemobrain and neuropathic pain. This study investigates the capacity of nasally administered mesenchymal stem cell-derived mitochondria coated with dextran-triphenylphosphonium polymer (coated mitochondria) to reverse these neurotoxicities. Nasally administered coated mitochondria are rapidly detectable in macrophages in the brain meninges but do not reach the brain parenchyma. The coated mitochondria change expression of >2400 genes regulating immune, neuronal, endocrine and vascular pathways in the meninges of mice treated with cisplatin. Nasal administration of coated mitochondria reverses cisplatin-induced cognitive deficits and resolves neuropathic pain at a >55-times lower dose compared to uncoated mitochondria. Reversal of these neuropathologies is associated with resolution of cisplatin-induced deficits in myelination, synaptosomal mitochondrial integrity and neurogenesis. These findings demonstrate that nasally administered coated mitochondria promote resolution of chemobrain and peripheral neuropathy, thereby identifying a novel facile strategy for clinical application of mitochondrial donation and treating central and peripheral nervous system pathologies by targeting the brain meninges.
Enabling Technologies for Mobile Services: The MobiLife Book (2007)

The expected future evolution of mobile and wireless communication technologies will enable a whole new generation of mass-market-scale ubiquitous services and applications. The challenge now is to research and develop applications and services addressing the true needs of the end-users, and to provide engaging and sustaining added value to them. Enabling Technologies for Mobile Servicestakes a comprehensive approach on these challenges and provides practical guidelines on building new, innovative applications and services. It shares knowledge gained from a collaborative research project where the methods and technologies were applied and utilised. This book is ideal for professionals working with enabling technologies and service architecture in companies. It will also be of interest to academics and students studying applications/services, enabling technologies and service architectures at the universities and to anyone interested in the general issues surrounding mobile technology. Key features: Covers key topics in the B3G area including applications and services from the users, key enabling technologies, regulatory and business models, end-user evaluations and applications/services creation points of view Explains the results of major collaborative (industry-academia-SMEs) MobiLife research project Builds on previous and parallel interaction with the Wireless World Research Forum Explores pioneering legal/regulatory analysis of the challenges related to new, advanced application/service solutions including personalisation and DRM Presents qualitative evaluations and field studies of more than 250 end-users in Italy and Finland Additional material available on companion website
Tralokinumab treatment improves the skin microbiota by increasing the microbial diversity in adults with moderate-to-severe atopic dermatitis: Analysis of microbial diversity in ECZTRA 1, a randomized controlled trial (2022)

Our findings indicate specific targeting of the interleukin 13 cytokine with tralokinumab can directly and/or indirectly improve microbial dysbiosis seen in AD skin.
PTHR1 Genetic Polymorphisms Are Associated with Osteoporosis among Postmenopausal Arab Women (2021)

The parathyroid hormone 1 receptor (PTHR1) plays a crucial role in calcium homeostasis and bone metabolism. However, its genetic role in regulating bone turnover markers (BTMs) in postmenopausal osteoporosis (PMO) remains unclear. Herein, we explored parathyroid hormone (PTH) and PTHR gene variant susceptibility to osteoporosis and their association with various circulating BTM and inflammatory markers in postmenopausal women of Arab ethnicity. In total, 600 postmenopausal Arab women (300-PMO and 300-control) were genotyped for selected SNPs in PTH (rs1459015, rs307253, rs6054, rs307247, rs10500783 and rs10500784), PTHR1 (rs6442037, rs1138518, and rs724449 SNPs) and PTHR2 (rs9288393, rs10497900, and rs897083). Anthropometrics, BTMs, and inflammatory markers were measured. Bone mineral density (BMD) was measured at the lumbar spine L1-L4 and the femoral neck using dual-energy X-ray absorptiometry (DXA). PTHR1 rs1138518 genotype C/T was found to be a significant risk factor for PMO (OR = 1.49, 95% CI 1.0-2.1, <i>P</i> = 0.03). The genotypes C/T and T/T of PTHR1 rs1138518 were associated with 25-hydroxy-vitamin D (25(OH)D) regulation. In the PMO group, carriers of the C/T genotype had significantly lower 25(OH)D levels than carriers of the same genotypes in the control group (59.9 (36.7-92.4) nmol/l and 66.4 (43.5-87.8) nmol/l, respectively; <i>P</i> = 0.048]. Our study concludes that the PTHR1 rs1138518 genotype could be a potential risk factor for osteoporosis and 25(OH)D regulation in Arab women with PMO.
Optically active transition-metal complexes. Part 79. Optically active organoiron enantiomers formed by HF cleavage of the P–N bond in the aminophosphine ligand of separated diastereoisomers (1982)

Liquid HF cleaves the P–N bond in [Fe(η-C5H5)(CO)I{P(C6H5)2-N(CH3)CH(CH3)(C6H5)}](1), without attack at the Fe–I bond, to give quantitatively [Fe(ηC5H5)(CO)I{P(C6H5)2F}](2). Using the aminophosphine with (S) configuration at the asymmetric carbon atom in the amino-component, (1) forms a pair of diastereoisomers. (+)365 and (–)365, which only differ in the configuration at iron. The HF cleavage can be used to convert the separated (+)365 and (–)365 diastereoisomers of (1) into the corresponding enantiomers of (2). Extensive racemisation with respect to the chiral Fe atoms during the HF reaction can be excluded.
Techniques for minimizing error propagation in decision feedback detectors for recording channels (2001)

Decision feedback equalization (DFE) is a low-cost approach for signal detection in magnetic recording channels. However it suffers from the phenomenon of error propagation (EP). In this paper two approaches are proposed for minimizing EP in DFE. The first approach imposes appropriate constraints on the feedback equalizer. The second approach uses simple threshold techniques to detect the presence of decision errors and to either correct these errors or minimize the possibility of further errors. Computer simulations show that the proposed techniques reduce EP very significantly. Theoretical analyses of the threshold techniques are presented to quantify the associated false and correct detection probabilities. By combining the analysis with an existing EP simulation method, a fast simulation procedure is derived for estimating EP and bit error rate (BER).
The role of hydrophobic, aromatic and electrostatic interactions between amino acid residues and a titanium dioxide surface (2018)

Understanding the nature of interactions between inorganic surfaces and biomolecules, such as amino acids and peptides, can enhance the development of new materials. Here, we present single molecule force spectroscopy (SMFS) measurements of the interactions between an atomic force microscopy (AFM) probe, modified with various amino acids, and a titanium dioxide surface. Specifically, we study the affinity of amino acids toward a titanium dioxide surface bearing hydrophobic (Leu), aromatic (Phe) and hydrophilic (Orn) residues. We find that aromatic interactions dominate over aliphatic in their affinity to the titanium dioxide surface. In addition, we show that by combining aromatic and hydrophilic moieties in a single amino acid (NH2-Phe), the adhesion of the latter to the surface increases. Furthermore, the affinity of positively charged amino acids to the titanium dioxide surface is higher than that of uncharged, and can be increased more, with elevating the pH of the buffer above the pKa of the basic residues. The kinetic and thermodynamic parameters imply that the dynamics of the surface-amino acid interface are mostly governed by hydrophobic interactions.
Cu/HP20-Catalyzed Solvent-Free Huisgen Cycloaddition at Ordinary Temperatures (2013)

We have developed an environmentally friendly and highly efficient solvent-free Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction using a polymer-supported copper catalyst (Cu/HP20).Substrates poorly soluble in common organic solvents are also applicable to the present cycloaddition reaction without any solvents and provide the corresponding 1,4-triazole in high yields.
Physical origin of mode instabilities in high-power fiber laser systems (2012)

Mode instabilities, i.e. the rapid fluctuations of the output beam of an optical fiber that occur after a certain output power threshold is reached, have quickly become one of the most limiting effects for the further power scaling of fiber laser systems. Even though much work has been done over the last year, the exact origin of the temporal dynamics of this phenomenon is not fully understood yet. In this paper we show that the origin of mode instabilities can be explained by taking into account the interplay between the temporal evolution of the three-dimensional temperature profile inside of the active fiber and the related waveguide changes that it produces via the thermo-optical effect. In particular it is proposed that non-adiabatic waveguide changes play an important role in allowing energy transfer from the fundamental mode into the higher order mode. As it is discussed in the paper, this description of mode instabilities can explain many of the experimental observations reported to date.
A Novel Approach to the Treatment of Gunshot Injuries to the Sacrum (2003)

Two patients (a 17-year-old male and a 19-year-old female) sustained single gunshot wounds to the abdomen. Given the nature of their wounds and presumed peritoneal penetration they were taken urgently to the operating room for exploratory laparotomy. Both patients sustained multiple intra-abdominal injuries including gastric and small and large bowel perforations. Given the extensive nature of these injuries both patients required bowel resections. Upon further exploration they were both noted to have significant bleeding from the bony aspect of their sacrum. A surgical hemostat (CoStasis; Cohesion Technologies, Inc., Palo Alto, CA) (4.5-9.0 cm3) was directly applied to the injured area of the sacrum in both cases after standard surgical hemostatic techniques were unsuccessful. After application no further attempts of hemostatic control by standard methods were attempted. In both cases the sacral bleeding ceased without any further surgical intervention. Postoperatively neither patient rebled from the sacral injuries. Penetrating injuries to the sacrum can be life threatening and difficult to control with standard surgical hemostatic techniques. CoStasis, a new surgical hemostat, was effective in obtaining immediate and definitive hemostatic control. Future prospective trials on the use of CoStasis in trauma patients are warranted.
Three-wave mixing in the GHz range with Josephson junctions and resonators (2012)

International audience
Human La binds mRNAs through contacts to the poly(A) tail (2018)

In addition to a role in the processing of nascent RNA polymerase III transcripts, La proteins are also associated with promoting cap-independent translation from the internal ribosome entry sites of numerous cellular and viral coding RNAs. La binding to RNA polymerase III transcripts via their common UUU-3'OH motif is well characterized, but the mechanism of La binding to coding RNAs is poorly understood. Using electromobility shift assays and cross-linking immunoprecipitation, we show that in addition to a sequence specific UUU-3'OH binding mode, human La exhibits a sequence specific and length dependent poly(A) binding mode. We demonstrate that this poly(A) binding mode uses the canonical nucleic acid interaction winged helix face of the eponymous La motif, previously shown to be vacant during uridylate binding. We also show that cytoplasmic, but not nuclear La, engages poly(A) RNA in human cells, that La entry into polysomes utilizes the poly(A) binding mode, and that La promotion of translation from the cyclin D1 internal ribosome entry site occurs in competition with cytoplasmic poly(A) binding protein (PABP). Our data are consistent with human La functioning in translation through contacts to the poly(A) tail.
Improved Nerve Visualization in Head and Neck Surgery Using Mueller Polarimetric Imaging: Preclinical Feasibility Study in a Swine Model (2021)

MPI is a potentially complementary intraoperative tool for nerve identification in adjacent tissues.
ChemInform Abstract: THE SYNTHESIS OF NUCLEOSIDES DERIVED FROM 5‐ETHYNYLURACIL AND 5‐ETHYNYLCYTOSINE (1979)

Abstract Umsetzung der Trimethylsilyl‐Derivate (I) mit der acylierten Ribose (II) gibt die ge schützten Nucleoside (IIIa) bzw. (IIIb); Abspaltung der Benzoy liefert die freien Verbindungen (IIIc) bzw. (IIId) Bei der Umsetzung von (I) mit d acylierten Halogenose (IV) werden die Nucl α‐Anomeren (VIa) bzw. (VIb) gebildet (nachfolg (Vc), (Vd), (VIc) bzw. (VId)).
ChemInform Abstract: The Regioselective Preparation of 1,3‐Diketones within a Micro Reactor. (2002)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
The Microbial Community of the Cystic Fibrosis Airway Is Disrupted in Early Life (2014)

The microbial communities in the lower airways of stable children with CF and children without CF show significant differences in overall diversity. These discrepancies indicate a disruption of the airway microflora occurring early in life in children with CF.
Pseudo-Perforation of the Pacing Leads in Patients Underwent Lead Extraction (2011)

Aim: The device leads perforating the myocardium are contraindicated for percutaneous lead extraction (LE). The purpose of this study is to investigate the usefulness of multidetector computed tomography (MDCT) or angiography to identify the perforating lead before LE. Methods: Among consecutive 44 patients underwent LE, we performed MDCT in 30 patients and angiography of RA, RV in 31 patients. The images were investigated to assess the possibility of lead perforation. Results: In 9 patients, the tip of the leads seemed protruding from the myocardium (RV apex n=7, RA appendage n=2). LE was performed under the thoracotomy in 6 patients with possible perforation, considering for the risk of cardiac tamponade. In 6 patients (67%) with possible perforation, the percutaneous LE was succeeded without any complications. In 3 patients (33%), the leads were surgically extracted. In cases with thoracotomy, surgical observation revealed that 2 RA and 1 RV leads were sticking out of the myocardium, but covered with pericardium and fat pad (pseudo-perforation). Two RA leads underwent surgical removal, but the RV lead was safely extracted by percutanous technique. Conclusion: Though the percutaneous LE was safely performed even in most patients with the findings of pseudo-perforation, we have to pay attention not to make the complications in these patients.
Video stabilisation with total warping variation model (2017)

This study proposes a robust approach to stabilise videos with a new variational minimising model. In video stabilisation, accumulation error often occurs in cascaded transformation chain‐based methods. To alleviate accumulation error, a new total warping variation (TWV) model is proposed, which describes the smoothness of stabilised camera motion and calculates all the warping transformations efficiently. After estimating original motion parameters based on a 2D similarity transformation model, the corresponding warping parameters are calculated under the TWV minimising framework, where the separable property of the motion parameters is utilised to obtain a closed‐form solution. The proposed method provides robust, smooth and precise motion trajectories after stabilisation. Furthermore, an iterative TWV method is introduced to reduce high‐frequency jitters as well as low‐frequency motions. Moreover, an online TWV method is presented for a long video sequence streaming by adopting a sliding windowed approach. Experimental results on various shaky video sequences show the effectiveness of the proposed method.
CUPID: A Protocol Development Environment (1983)

This paper describes research conducted towards Columbia's unified Protocol Implementation and Design (CUPID) environment. CUPID research aims at the integration and automation of protocol design and implementation tools. CUPID uses an algebraic representation of protocols based, in part, upon a variant of Milner's calculus of communicating systems (CCS). Communication behaviors are represented in terms of expressions of a universal algebra. A key notion to the automation of protocol development functions is that of a valuation over the algebra of communication behaviors. A valuation maps communication behaviors to expressions in other algebras (e.g., an algebra of delay distributions used for performance analysis). This allows one to proceed and compute attributes of communication behaviors over the respective algebras using a formal valuation process. We provide a brief introduction to CCS in the context of modelling protocol behaviors. This is followed by a brief summary of how the algebraic valuation mechanism may be used to support the different functions of a protocol design environment: multiple concurrent specifications, automated functional and performance analysis and automated test generation and performance simulation.
Beam amplification via multiwave mixing in stationary and transient thermal gratings (1987)

We present a detailed theory of multiwave mixing via a laser-induced thermal grating in a thin film. The two incident lasers consist of one strong pump and a relatively weaker probe beam. These lasers are coherent with respect to each other but may be frequency shifted. This produces a stationary (frequency shift is zero) or a moving (non-zero frequency shift) intensity grating on the film. This in turn creates a spatially coincident or a nonlocal refractive-index grating. We solved the 3-D heat diffusion problem as well as the coupled Maxwell wave equations for the pump, probe, and various diffracted beams in a self-consistent manner. Under easily realized geometries and using high thermal index materials such as liquid crystals, very large amplification of the probe beam (more than 20) can be easily achieved with a cw pump beam of a few W/cm 2 . Experimentally, we have verified the theoretical predictions using cw and pulsed CO 2 lasers. The wave mixing effects are studied as a function of pump beam intensities, grating constants, temperature, pump-to-pump ratio, and sample thickness.