gebhart/patrepeval huggingface dataset:
Serum-mediated resolution of Lyme arthritis in mice. (1996)

Arthritis and carditis were mildly improved upon adoptive transfer of T cell enriched lymphocyte populations from Borrelia burgdorferi-infected (B. burgdorferi) (immune) compared with naive immunocompetent mice into B. burgdorferi-infected, severe combined immunodeficient (SCID) mice. Despite the relative purity of T cells in transferred cells, recipient mice seroconverted to B. burgdorferi. Thus, the effect could not be attributed to T cells alone. Passive transfer of serum from actively infected immunocompetent mice (immune serum) to SCID mice at the time of or before B. burgdorferi inoculation, or on Days 4, 8, and 12 after inoculation prevented or cured (respectively) infection and disease when examined at 15 days. Transfer of immune serum on Days 12, 16, 20, 24, and 28 did not clear infection at Day 30 but resulted in resolution of arthritis, indicating that immune serum can cause resolution of joint disease. Immune serum treatment could maintain arthritis resolution for up to 60 days. Immune serum from mice infected for 90 days or 15 months both had strong protective, post-infection, and arthritis-modulating activity, whereas hyperimmune serum to heat-killed B. burgdorferi or recombinant outer surface protein (Osp) A protected mice against infection when given on Day 0--but not at later intervals--and did not modulate disease. Immune serum from 90-day infected mice labeled spirochetes in joint tissues of SCID mice by immunohistochemistry, but hyperimmune serum to heat-killed B. burgdorferi or OspA did not. These studies suggest that the biologically active properties of immune serum may be directed toward yet to be defined, in vivo-expressed antigens of B. burgdorferi.
Preparation, Structure, and Electrochemistry of Layered Polyanionic Hydroxysulfates: LiMSO4OH (M = Fe, Co, Mn) Electrodes for Li-Ion Batteries (2013)

The Li-ion rechargeable battery, due to its high energy density, has driven remarkable advances in portable electronics. Moving toward more sustainable electrodes could make this technology even more attractive to large-volume applications. We present here a new family of 3d-metal hydroxysulfates of general formula LiMSO4OH (M = Fe, Co, and Mn) among which (i) LiFeSO4OH reversibly releases 0.7 Li(+) at an average potential of 3.6 V vs Li(+)/Li(0), slightly higher than the potential of currently lauded LiFePO4 (3.45 V) electrode material, and (ii) LiCoSO4OH shows a redox activity at 4.7 V vs Li(+)/Li(0). Besides, these compounds can be easily made at temperatures near 200 °C via a synthesis process that enlists a new intermediate phase of composition M3(SO4)2(OH)2 (M = Fe, Co, Mn, and Ni), related to the mineral caminite. Structurally, we found that LiFeSO4OH is a layered phase unlike the previously reported 3.2 V tavorite LiFeSO4OH. This work should provide an impetus to experimentalists for designing better electrolytes to fully tap the capacity of high-voltage Co-based hydroxysulfates, and to theorists for providing a means to predict the electrochemical redox activity of two polymorphs.
Phase equilibria for water–methanol mixtures in perfluorosulfonic‐acid membranes (2001)

Abstract A new apparatus was constructed for precise measurements of water–methanol up‐take compositions in a membrane. Uptake concentrations of methanol and water in a Nafion 117 membrane were measured as a function of methanol mole fraction in a liquid‐methanol–water mixture for the temperature range 298 to 333 K. Also, uptake concentrations of methanol and water were determined for a second‐cycle uptake run. All methanol–water compositions were determined by gas chromatography. The results were quantitatively described by either one of two thermodynamically consistent equations derived from models for the Gibbs energy of the system.
trans‐2,5‐Disubstituted Pyrrolidines: Rapid Stereocontrolled Access from Sulfones. (2007)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A discovery of glycyrrhizin synthase in a medical plant, liquorice [Glycyrrhiza uralensis]. (2009)

Mitochondria are an important energy source in skeletal muscle. A main function of mitochondria is the generation of ATP for energy through oxidative phosphorylation (OXPHOS). Mitochondrial defects or abnormalities can lead to muscle disease or multisystem disease. Mitochondrial dysfunction can be caused by defective mitochondrial OXPHOS, mtDNA mutations, Ca<sup>2+</sup> imbalances, mitochondrial-related proteins, mitochondrial chaperone proteins, and ultrastructural defects. In addition, an imbalance between mitochondrial fusion and fission, lysosomal dysfunction due to insufficient biosynthesis, and/or defects in mitophagy can result in mitochondrial damage. In this review, we explore the association between impaired mitochondrial function and skeletal muscle disorders. Furthermore, we emphasize the need for more research to determine the specific clinical benefits of mitochondrial therapy in the treatment of skeletal muscle disorders.
Pathophysiology of chest pain in patients with cardiomyopathies and normal coronary arteries. (1982)

To clarify the pathogenesis of chest pain in patients with cardiomyopathies, we compared coronary blood flow and other indicators of ischemia at rest and during pacing-induced tachycardia in nine patients with cardiomyopathy (four hypertrophic and five congestive) and in five control subjects. Coronary blood flow was reduced at rest and during pacing in cardiomyopathy patients compared with controls. In patients with hypertrophic cardiomyopathy, pacing induced chest pain in all, increased ST-segment depression in three patients and increased coronary venous lactate concentration. With pacing, two of five patients with congestive cardiomyopathy had chest discomfort and three had increased ST-segment depression, but coronary venous lactate concentration did not change significantly. In both groups of cardiomyopathies, the ratio of the systolic and diastolic pressure-time indexes tended to decrease more than in controls during pacing. Thus, myocardial perfusion is decreased in patients with cardiomyopathy, both at rest and during pacing. The changes detected during pacing point to subendocardial ischemia as the likely mechanism for angina in hypertrophic and possibly also in congestive cardiomyopathy.
MDR-Tuberkulose in der Schwangerschaft: Konsequenzen für die Therapie, den Geburtsmodus und die Prävention beim Kind – Ein Fallbericht (2014)

Das Resistenzprofil der Mykobakterien, die Embryo- bzw. Fetotoxizität der antimykobakteriellen Substanzen, das peripartale Infektionsrisiko des Kindes, die Überwachung des Kindes postpartal und das postpartale Infektionsrisiko für das Kind.
Notes - Basic Alcoholysis of the Trifluoromethyl Group in 1,1,1-Trifluoro-2,2-diarylethanes (1956)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNotes - Basic Alcoholysis of the Trifluoromethyl Group in 1,1,1-Trifluoro-2,2-diarylethanesR. Mechoulam, S. Cohen, and A. KaluszynerCite this: J. Org. Chem. 1956, 21, 7, 801–803Publication Date (Print):July 1, 1956Publication History Published online28 February 2003Published inissue 1 July 1956https://pubs.acs.org/doi/10.1021/jo01113a605https://doi.org/10.1021/jo01113a605research-articleACS PublicationsRequest reuse permissionsArticle Views118Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Ultraviolet-inscribed long period gratings in all-solid photonic bandgap fibers (2008)

Long period fiber gratings are fabricated in the cladding rods of all-solid photonic bandgap fibers (PBGFs) by point-by-point side UV illumination. Resonant couplings from fundamental mode to guided and radiative supermodes (rod modes), and bandgap-like modes are identified. We obtained a detailed insight over the modal and dispersive properties of the PBGF through a series of theoretical and experimental investigations on the spectral characteristics and the responses to temperature and high-index liquid of the LPGs.
Pilot-Based Channel Quality Reporting for OFDMA/TDD Systems with Cochannel Interference (2007)

This paper proposes pilot-based channel quality reporting for orthogonal frequency division multiple access/time division duplex (OFDMA/TDD) systems with cochannel interference. In the proposed method, a terminal reports his channel quality in multiple subbands to base station (BS) using channel reciprocity of TDD systems. The terminal transmits uplink pilot signals in the subbands with different transmit power which is inversely proportional to the subband-based interference power. The BS can obtain knowledge of the terminal's received signal-to-interference-plus-noise power ratio on subband basis, measuring the pilot signal power. In performance evaluation, accuracy of channel quality reporting and amount of uplink signalling are examined. From numerical results, it is found that the proposed method becomes effective as the number of subbands and terminals for channel quality reporting increases.
Reflectance-Correcting Pyrometry in Thin Film Deposition Applications (2003)

A detailed study of an emissivity-correcting pyrometer instrument for measuring wafer surface temperatures during thin film growth is presented. The basic physics is reviewed and preliminary data showing a temperature over-compensation artifact is shown. The rest of the report presents an exhaustive analysis of the potential sources for the temperature over-compensation effect. This analysis yields an in situ calibration method that can be used to remove temperature over-compensation artifacts that arise from any first-order systematic error in either the reflectance or thermal emission measurement. With corrections applied, artifact-free surface temperatures can be measured with a precision of a few {sup o}C over a wide range of wafer emissivities.
Editorial Commentary: Anterior Cruciate Ligament Remnant: What to Do With It? (2016)

There is considerable current controversy regarding surgical techniques for anterior cruciate ligament reconstruction. Yet despite constant evolution, clinical outcomes have changed very little. Subtle changes in surgical techniques are unlikely to have material impacts on patient-reported outcomes.
A Case Study in Translating Medical Evidence into Mobile Decision Support (2012)

Abstract Background: Combination oral contraceptives are prescribed 10 million times a year in the United States alone. Prescribers have more than 70 oral‐contraceptive choices, but individual women's medical conditions may make some contraceptives inappropriate or dangerous. Traditional sources of prescribing information are impractical at the point of care. Mobile apps are revolutionizing clinical workflow, but none have been deployed for oral‐contraceptive selection. Objective/Purpose: to design of an evidence‐based interactive tool for selecting oral contraceptives, as a model for dissemination of clinical practice guidelines to clinical settings via mobile applications. Methods: I indexed the practice guidelines for hormonal contraception from the World Health Organization and the American Congress of Obstetricians and Gynecologists, and expert recommendations from two contraceptive textbooks. I gathered the rules into IF‐THEN use cases, annotated with evidence quality and prioritized by likelihood and importance, and classified contraceptive choices into specific recommendation groups. Results: The sources yielded 32 guidelines and 24 expert recommendations using a total of 73 data elements, mostly TRUE/FALSE choices or numeric values. Organizing these into 22 use cases evaluating one to eight data elements each, few enough to fit on a smartphone screen, permits the entire questionnaire to be navigated in 22 or fewer screens. Discussion/Conclusions: Handheld clinical applications can facilitate evidence‐based medicine, and reduce medical errors, by moving the best available medical knowledge from laborintensive traditional resources to prescribers' fingertips. They may create privacy and data‐security risks, but limiting apps to anonymous single‐use queries obviates these. Potential enhancements include additional object‐oriented treatment domains, automatically updating rules engines using the Guideline Elements Model, and allowing user communities to add rules.
ATM input-buffered switches with the guaranteed-rate property (2002)

There is considerable interest in the provision of guaranteed-rate services for IP and ATM networks. Simultaneously, bandwidth demands make input-buffered architectures attractive, and in some cases, necessary. We consider the problem of how to support guaranteed-rate services in a single-stage, input-buffered switch suitable for a LAN switch, an ATM switch or an IP router. Such a switch must be feasible at high transmission speeds, offering both guaranteed-rate performance for CBR channels (e.g. for real-time connections) and best-effort services for traditional data traffic. We consider a switch scheduling mechanism that employs idling hierarchical round-robin (HRR) scheduling and fabric arbitration at the connection-level for guaranteed-rate service using the Slepian-Duguid algorithm. The switch uses cell level arbitration for best-effort service. This overall switch scheduling mechanism is a variation of DEC's AN2 design.
High-order harmonic generation with a 1.5 &#x03BC;m self-phase-stabilized parametric source (2008)

We generated high-order harmonics with self-phase-stabilized near-IR pulses produced by a parametric source. We observed a significant cutoff extension whit respect to 800-nm driving pulses at comparable peak intensity. This result represents a step forward the generation of single attosecond pulses with photon energies exceeding 100 eV.
Infrastructureless Inter-Vehicular Real-Time Route Guidance (2008)

This paper presents an inter-vehicular communication (IVC)-based algorithm for real-time route guidance in urban traffic networks. It is built on information sharing among some searcher vehicle and candidate vehicles traveling in the same direction, to the same destination and within a specific communication range. The paper discusses in details the algorithmic procedure and conditions for information sharing. A microscopic simulation model is utilized to assess the effectiveness of the algorithm against another benchmark algorithm; namely, centralized shortest path algorithm. Comparisons of the two algorithms' average travel time, and overall network productivity are presented. The algorithms performances are captured for various scenarios reflecting network congestion levels, link speeds and link lengths.
DC Electric Metamaterial Behaviour in Tuned Fused Deposition Modelling Prints (2021)

This paper shows the realization of electric metamaterials with Fused Deposition Modelling by tuning the nozzle temperature, bed temperature and extrusion width to achieve anisotropic electrical conduction. The temperatures influence the magnitude of the contact resistance between printed lines, whereas the extrusion width determines the number of contacts per unit length. Electric metamaterials are interesting for sensing, e.g. by concentrating the current to achieve highly sensitive spots. In this work such a concentrator is 3D-printed and its operation is demonstrated through IR thermography and voltage measurements, as well as supported by FEM simulations.
The Role of Axial Compressive and Quadriceps Forces in Noncontact Anterior Cruciate Ligament Injury (2011)

Compressive and quadriceps forces contribute to noncontact ACL injury and should be taken into account when developing ACL injury prevention programs and rehabilitation after ACL reconstruction.
A methodology to assess and improve the physics consistency of an artificial neural network regression model for engineering applications (2022)

Abstract In recent times, artificial neural networks (ANNs) have become the popular choice of model for researchers while performing regression analysis between inputs and output. However; in scientific and engineering applications, developed ANN regression model is often found to be inconsistent with the physical laws. This is due to the fact that ANNs are purely based on data and do not have any understanding of underlying physical laws. Alternate ANN frameworks like PGNN (Physics guided neural network) has been proposed in literature which incorporate physics loss function in the overall loss function to partially alleviate this issue. However, these frameworks don’t evaluate the physics consistency of relationship between inputs and output mapped by the ANN model which is the source of all physics inconsistencies. Hence, the present paper presents a methodology to assess and improve the physics consistency of the input output relationship mapped by the ANN regression model. The developed methodology can therefore be used to develop physics consistent ANN regression model. The heart of the methodology is an inferencing algorithm which interprets the input output relationship mapped by the ANN regression model. The inferencing algorithm is based on Taylor series and decomposes the ANN regression model into several region-wise polynomial models. Moreover, the inferencing algorithm can also find regions of singular zones in the ANN model predictions. The region-wise polynomial from inferencing algorithm can be used to assess the physics consistency of the ANN model. In the region of physics inconsistency, additional data points can be added and the ANN model can be re-trained. In cases, where the addition of data points is not possible, a physics based loss function can be used. The developed methodology is illustrated using several datasets. The developed methodology will help engineers and researchers built physics consistent ANN regression models.
Integrating DfM components into a cohesive design-to-silicon solution (Invited Paper) (2005)

Two primary tracks of DfM, one originating from physical design characterization, the other from low-k<sub>1</sub> lithography, are described. Examples of specific DfM efforts are given and potentially conflicting layout optimization goals are pointed out. The need for an integrated DfM solution than ties together currently parallel DfM efforts of increasing sophistication and layout impact is identified and a novel DfM-enabling design flow is introduced.
The dynamic lot-sizing model with backlogging: A simpleo(n logn) algorithm and minimal forecast horizon procedure (1993)

We develop a simple O(n log n) solution method for the standard lot-sizing model with backlogging and a study horizon of n periods. Production costs are fixed plus linear and holding and backlogging costs are linear with general time-dependent parameters. The algorithm has linear [O(n)] time complexity for several important subclasses of the general model. We show how a slight adaptation of the algorithm can be used for the detection of a minimal forecast horizon and associated planning horizon. The adapted algorithm continues to have complexity O(n log n) or O(n) for the above-mentioned subclasses of the general model. © 1993 John Wiley & Sons, Inc.
CliqueSquare: efficient Hadoop-based RDF query processing (2013)

National audience
β-Phenylmercapto-cis- and trans-cinnamic Acids (1960)

Journal Article β-Phenylmercapto-cis- and trans-cinnamic Acids Get access Morifusa Eto, Morifusa Eto Department of Agricultural Chemistry, Kyushu University, Fukuoka Search for other works by this author on: Oxford Academic Google Scholar Yasuyoshi Oshima Yasuyoshi Oshima Department of Agricultural Chemistry, Kyushu University, Fukuoka Search for other works by this author on: Oxford Academic Google Scholar Bulletin of the Agricultural Chemical Society of Japan, Volume 24, Issue 5, 1 July 1960, Pages 473–480, https://doi.org/10.1080/03758397.1960.10857693 Published: 01 July 1960 Article history Received: 08 December 1959 Published: 01 July 1960
Field theory design of a corrugated septum OMT (2002)

The authors present a rigorous design method for corrugated septum orthomode transducers (OMTs) which combines the compactness advantage of the stepped septum structure with the phase matching potential of corrugated waveguide polarizers. The structure under investigation is composed of standard field theory key-building blocks, the double-step discontinuity, the waveguide-to-ridged-waveguide transition, and the transition waveguide to septated waveguide. Based on the modal scattering matrix method, the design takes into account the influence of both the finite septum thickness and the higher-order mode interaction at all discontinuities. Computer-optimized design data are given for a Ku-band waveguide corrugated septum polarizer, achieving a return loss of more than 20 dB together with a 90 degrees +0 degrees /-3 degrees differential phase shift for about 10% bandwidth. The theory is verified by measurements.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Spectrophotometric determination of carboxylic acids by the formation of hydroxamic acids with dicyclohexylcarbodiimide (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSpectrophotometric determination of carboxylic acids by the formation of hydroxamic acids with dicyclohexylcarbodiimideYasuhiko. Kasai, Takenori. Tanimura, and Zenzo. TamuraCite this: Anal. Chem. 1975, 47, 1, 34–37Publication Date (Print):January 1, 1975Publication History Published online1 May 2002Published inissue 1 January 1975https://pubs.acs.org/doi/10.1021/ac60351a047https://doi.org/10.1021/ac60351a047research-articleACS PublicationsRequest reuse permissionsArticle Views738Altmetric-Citations41LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts