gebhart/patrepeval huggingface dataset:
A Mechanical Model of the Human Ankle in the Transverse Plane During Straight Walking: Implications for Prosthetic Design (2008)

In order to protect sensitive residual limb soft tissues, lower limb prostheses need to control torsional loads during gait. To assist with the design of a torsional prosthesis, this paper used simple mechanical elements to model the behavior of the human ankle in the transverse plane during straight walking. Motion capture data were collected from ten able-bodied subjects walking straight ahead at self-selected walking speeds. Gait cycle data were separated into four distinct states, and passive torsional springs and dampers were chosen to model the behavior in each state. Since prosthetic design is facilitated by simplicity, it was desirable to investigate if elastic behavior could account for the physiological ankle moment and include viscous behavior only if necessary to account for the inadequacies of the spring model. In all four states, a springlike behavior was able to account for most of the physiological ankle moments, rendering the use of a damper unnecessary. In State 1, a quadratic torsional spring was chosen to model the behavior, while linear torsional springs were chosen for States 2-4. A prosthetic system that actively changes stiffness could be able to replicate the physiological behavior of the human ankle in the transverse plane. The results of this study will contribute to the mechanical design and control of a biomimetic torsional prosthesis for lower limb amputees.
Bifurcation Analysis of a Diffusive Predator–Prey Model with Bazykin Functional Response (2019)

This paper deals with a diffusive predator–prey model with Bazykin functional response. The parameter regions for the stability and instability of the unique constant steady state are derived. The Turing (diffusion-driven) instability which induces spatial inhomogeneous patterns, the existence of time-periodic orbits which produce temporal inhomogeneous patterns, the existence and nonexistence of nonconstant steady state positive solutions are proved. Numerical simulations are presented to verify and illustrate the theoretical results.
Improvement in the interferometric measurement of subangstrom vibrations (1976)

Improvements in the calibration of a condenser-microphone-stabilized Michelson interferometer for the measurement of subangstrom vibrations are described. They consist of the elimination of errors caused by the fact that the sensitivity of the microphone is dependent on its bias voltage, and a new design of the stabilizing circuit.
Soluble plasma HLA peptidome as a potential source for cancer biomarkers (2010)

The HLA molecules are membrane-bound transporters that carry peptides from the cytoplasm to the cell surface for surveillance by circulating T lymphocytes. Although low levels of soluble HLA molecules (sHLA) are normally released into the blood, many types of tumor cells release larger amounts of these sHLA molecules, presumably to counter immune surveillance by T cells. Here we demonstrate that these sHLA molecules are still bound with their authentic peptide repertoires, similar to those of the membranal HLA molecules (mHLA). Therefore, a single immunoaffinity purification of the plasma sHLA molecules, starting with a few milliliters of patients' blood, allows for identification of very large sHLA peptidomes by mass spectrometry, forming a foundation for development of a simple and universal blood-based cancer diagnosis. The new methodology was validated using plasma and tumor cells of multiple-myeloma and leukemia patients, plasma of healthy controls, and with cultured cancer cells. The analyses identified thousands of sHLA peptides, including some cancer-related peptides, present among the sHLA peptidomes of the cancer patients. Furthermore, because the HLA peptides are the degradation products of the cellular proteins, this sHLA peptidomics approach opens the way for investigation of the patterns of protein synthesis and degradation within the tumor cells.
Adulando o usuário da demonstração contábil (2017)

O presente trabalho teve a finalidade de verificar se a apresentacao de demonstracoes contabeis junto com um texto ‘bajulando’ (adulando) o usuario seria capaz de influenciar de maneira positiva a imagem dos individuos a respeito do desempenho desta empresa. Para verificar isso, foram elaborados dois tipos de questionarios com identicas demonstracoes contabeis de uma empresa ficticia; o diferencial entre eles foi que um dos textos continha elogios aos investidores, como forma de bajula-los. O questionario foi aplicado em estudantes de contabilidade da Universidade de Brasilia (UnB). As questoes eram objetivas e deveriam ser respondidas com notas de zero a 10. Para comparar os resultados, foi realizado teste de media entre as notas dadas pelos respondentes e uma regressao linear multipla, sendo a variavel dependente a nota atribuida para o desempenho e as variaveis adulacao e caracteristicas dos respondentes como independentes. Em uma primeira regressao, a adulacao nao apresentou efeito significativo para o modelo. Uma segunda regressao, com a inclusao de uma variavel interativa, resultante da atuacao em conjunto das variaveis adulacao e idade, demonstrou que a adulacao seria significativa. Isto indica que a adulacao tem o efeito de melhorar a nota dada pelos respondentes a empresa, porem esse efeito diminui com o avanco da idade. Uma primeira possivel explicacao para o resultado obtido e que, a medida que os individuos ficam mais velhos, tornam-se menos suscetiveis a influencias emocionais. Outra possivel explicacao para o resultado e que os individuos mais velhos, por estarem em semestres mais avancados, possuem maior conhecimento teorico capaz de tornar sua analise mais imparcial e racional. Palavras-chave: Efeito Adulacao. Financas Comportamentais. Decisao de investimento. Demonstracoes Contabeis.
A model of GAA•TTC repeat expansion in human cell lines (2008)

Friedreich ataxia (FRDA) is a neurodegenerative disorder caused by GAA•TTC repeat expansion in the first intron of the frataxin gene (FXN). Expanded GAA•TTC repeat tracts reduce FXN gene expression in FRDA patients. The mechanisms responsible for GAA•TTC repeat expansion remain unclear. The development of a human cellular model of GAA•TTC repeat instability will provide an experimental system in order to better understand the mechanisms leading to GAA•TTC repeat expansion in FRDA. Our system employs reporter constructs containing uninterrupted GAA•TTC repeat tracts that have been integrated into a unique location in the genome of human embryonic kidney (HEK) 293 cell lines. PCR and Southern blot analysis of the GAA•TTC repeat sequences within these cell lines has revealed substantial instability, with a bias towards repeat expansion over time. Continued GAA•TTC repeat expansion in FRDA may contribute to the unrelenting progression of this disorder. The expansion of GAA•TTC repeat sequences in our cell lines reflects the dynamics of GAA•TTC repeat instability observed in FRDA, and could therefore serve as an experimental model to dissect the mechanisms contributing to this instability. This work was supported by NIH grant number R01NS046567 and by a grant from the Friedreich's Ataxia Research Alliance (FARA).
Creating synergy: Developing new forms of partnership between university and industry (2005)

An innovative university/industry partnership has been developed between the Australian Catholic University (ACU) and Centrelink (the Australian Government's Service Delivery Agency). This partnership has been established on a ‘no exchange of monies’ basis and has proved to provide clear specific benefits to the School of Social Work at ACU and Centrelink's National Social Work Services Team and also to both organisations more generally. The authors argue that this type of university/industry partnership offers a framework that has wide applicability in the human services where relationships between training institutions and ‘the field’ appear to be becoming increasingly difficult.
The newly discovered non A-E hepatitis viruses. (1996)

Two biotechnology companies have recently announced the discovery of 4 new hepatitis viruses, provisionally named HGV and GBV agents (GBV-A, GBV-B, and GBV-C). Using a molecular biological approach, the genomes of these viruses were identified from non-A-E hepatients patients who had no markers to any previously known hepatitis viruses. The new viruses are members of family Flaviviridae, and are closely related to hepatitis C virus (HCV). Preliminary studies show that the prevalence of GBV agents and HGV are alarmingly high in blood donors in the United States, Europe, Africa and Japan. The viruses are transmitted parenterally, similar to HCV and hepatitis B virus (HBV), Chronic infection is common and can lead to cirrhosis. Some chronic hepatitis cases caused by these viruses respond to interferon treatment. The viruses can coinfect with HCV and/or HBV. A number of questions about these new viruses remain to be answered, including the magnitude of the problems, clinical significance, mode of transmission and populations at risk, as well as the appropriate treatment.
Display of a Peptide Corresponding to the Dimer Structure of Protease Attenuates HIV-1 Replication (2001)

Current treatment of HIV-1-infected individuals involves the administration of several drugs, all of which target either the reverse transcriptase or the protease activity of the virus. Unfortunately, the benefits of such treatments are compromised by the emergence of viruses exhibiting resistance to the drugs. This situation warrants new approaches for interfering with virus replication. Considering the activation of protease in the virus particles, a novel strategy to inhibit HIV-1 replication was tested targeting the dimerization domain of the protease. To test this idea, we have selected four residues from the C terminus of HIV-1 protease that map to the dimer interface region of the enzyme. We have exploited Vpr to display the peptides in the virus particles. The chimeric Vpr exhibited expression and virion incorporation similar to wildtype Vpr. The virus derived from the HIV-1 proviral DNA containing chimeric Vpr sequences registered a reduced level of replication in CEM and CEM X 174 cells in comparison with viruses containing wildtype Vpr. Similar results were observed in a single-round replication assay. These results suggest that the intravirion display of peptides targeting viral proteins is a powerful approach for developing antiviral agents and for dissecting the dynamic interactions between structural proteins during virus assembly and disassembly.
Cochlear Potentials and Oxygen Associated with Hypoxia (1975)

In the guinea pig, during general hypoxia produced by shutoff of respiratory air, oxygen-sensitive microelectrodes detect a decrease in oxygen concentration in the fluids of the tunnel of Corti before detecting a decrease in scala media oxygen concentration. The present experiments were designed to measure the cochlear microphonic (CM) potential generated by the organ of Corti when vibrated by a microprobe on the basilar membrane along with the oxygen decline in both tunnel and scala media to see upon which source of oxygen CM is dependent. Because oxygen concentration in both areas can decrease considerably before CM is affected, the recovery following a brief period of hypoxia is a more accurate measure. Because CM starts a recovery before scala media oxygen, the positive endolymphatic potential (EP) was also measured to determine its role in the generation of CM. Our interpretation of the course of events is that CM is partially dependent upon oxygen supplied to the extracellular spaces of the organ of Corti by the spiral vessels and upon EP that, itself, is dependent upon several factors. The data indicate that EP plays a more complex role than that of providing a current flow for modulation by a resistance varying with vibration.
Perceptual quality adaptation (PQA) algorithm for 3GP and multitracked MPEG-4 content over wireless IP networks (2005)

Many adaptive delivery mechanisms have been devised for streaming multimedia over best-effort IP networks, such as the Internet. Most of these adaptive schemes do not consider the user's perception of quality when making adaptations. We describe a perceptual quality adaptation algorithm (PQA) and prototype system architecture that uses knowledge of user perceived quality to make adaptation decisions using an optimum adaptation trajectory. This optimum adaptation trajectory indicates how encoding quality should be adapted (upgraded/downgraded) with respect to user perceived quality in response to rapidly fluctuating network conditions. We present simulation results that demonstrate the behavior of a perceptual quality adaptation algorithm.
A high-luminosity position sensitive neutron detector for residual stress measurements (2002)

Because the diffraction angle is equal or close to 90/spl deg/ in residual stress measurements by neutron diffraction, the luminosity of the device can be increased by expansion of the detection window height without the deformation of the diffraction peak. A high luminosity position sensitive neutron detector has been designed and fabricated for measuring residual stress. The detector has a working window of 200 /spl times/ 100 mm/sup 2/. The detector has high efficiency, good position resolution, and linearity, small position error and low background counts. The detector characteristics are presented.
Multiple path-based approach to image-based street walkthrough: Research Articles (2005)

Image-based rendering for walkthrough in the virtual environment has many advantages should over the geometry-based approach, due to the fast construction of the environment and photo-realistic rendered results. In image-based rendering technique, rays from a set of input images are collected and a novel view image is rendered by the resampling of the stored rays. Current such techniques, however, are limited to a closed capture space. In this paper, we propose a multiple path-based capture configuration that can handle a large-scale scene and a disparity-based warping method for novel view generation. To acquire the disparity image, we segment the input image into vertical slit segments using a robust and inexpensive way of detecting vertical depth discontinuity. The depth slit segments, instead of depth pixels, reduce the processing time for novel view generation. We also discuss a dynamic cache strategy that supports real-time walkthroughs in large and complex street environments. The efficiency of the proposed method is demonstrated with several experiments. Copyright © 2005 John Wiley & Sons, Ltd.
Reversible binding of sulfur dioxide by polymer‐bound 1,3‐diene acceptor systems (1976)

Abstract In connection with the removal of sulfur dioxide from waste and flue gases the use of polymer‐bound 1,3‐diene systems has been investigated. Using divinylbenzene/styrene copolymers as the solid support, a number of immobilized 1,3‐dienes were prepared; these were able to bind sulfur dioxide by the formation of the corresponding sulfolene systems. Heating of the latter resulted in liberation of sulfur dioxide with the concomitant recovery of the original 1,3‐diene system. In most cases, upon repeated use of the polymer‐bound 1,3‐dienes, a decrease of the sulfur dioxide binding capacity was observed. Probably, inter‐chain reactions of the diene groups are responsible for this phenomenon.
Biochemical transformations of anilide herbicides in soil (1968)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBiochemical transformations of anilide herbicides in soilRichard. BarthaCite this: J. Agric. Food Chem. 1968, 16, 4, 602–604Publication Date (Print):July 1, 1968Publication History Published online1 May 2002Published inissue 1 July 1968https://doi.org/10.1021/jf60158a030Request reuse permissionsArticle Views95Altmetric-Citations73LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (1 MB) Get e-Alertsclose Get e-Alerts
On analysis and capacity estimation of TDMA/FDMA systems with interference adaptation dynamic channel allocation (2002)

It has been shown by simulation results that the interference adaptation dynamic channel allocation (IA-DCA) strategy is a promising channel allocation method in TDMA/FDMA systems. However, theoretical analysis of IA-DCA has not been thoroughly studied in the literature. The main difficulty is how to represent the interference in the IA-DCA environment. In this paper, the computation of both downlink and uplink co-channel interference in the IA-DCA environment is investigated. A framework for the analysis of 2-way balanced IA-DCA schemes is proposed. An asymptotic upper performance bound for the IA-DCA strategy is derived. The bound is used to estimate the maximum capacity enhancement the IA-DCA method can provide over the fixed channel allocation. Both a deterministic propagation model and a lognormal shadowing model are considered.
Large scale production of biomass-derived N-doped porous carbon spheres for oxygen reduction and supercapacitors (2013)

The urgent need for sustainable energy development depends on the progress of green technologies, which have steered hot research areas into environmentally benign approaches via inexpensive precursors and abundant resources obtained directly from nature for energy devices such as fuel cells and supercapacitors. By using fermented rice as starting materials, we herein demonstrate a facile, green and scalable approach to synthesize porous N-doped carbon spheres characterised by high specific surface areas (2105.9 m2 g−1) and high porosity (1.14 cm3 g−1), which exhibit not only excellent electrocatalytic activity toward the four-electron oxygen reduction reaction with long-term stability for fuel cells, but also have excellent resistance to crossover effects and CO poisoning superior to that of the commercial Pt/C catalyst. Furthermore, the naturally derived porous N-doped carbon spheres, used as the active electrode materials, present superior performance for capacitors with a capacitance of 219 F g−1 at a high discharge current density of 15 A g−1 and good cycling stability for over 4400 cycles. This work shows a good example for taking advantage of the abundant resources provided by nature, and opening the door for the creation of functional materials with promising applications in high-performance renewable devices related to energy conversion and storage.
Particle formation and growth in single-stage aerosol reactors (1991)

The feasibility of producing dense particles of a refractory material controlled by reaction of a vapor precursor has been examined experimentally and theoretically. Previous experiments that generated dense, spherical particles of silicon have been repeated with one modification. The peak temperature in the reactor was lowered to minimize sintering of any agglomerates formed early in the reactor. Agglomerate particles were generated with a peak reactor temperature of 1070 K. Raising the peak temperature to 1473 K resulted in nearly complete densification within a hot zone residence time of approximately 1 s. These results suggest that the dense particles previously reported resulted from sintering rather than vapor deposition. A simple model was used to probe the role of coagulation theoretically. Even with severely constrained reaction rates, a high concentration of fine particles was produced in the initial burst of nucleation. Coagulation plays a major role in the subsequent particle growth. The particles formed early in the reactor are efficient scavengers for clusters produced later, so only small clusters are formed after the initial nucleation burst for the conditions modeled. To suppress agglomeration, the number concentration produced by homogeneous nucleation must be reduced before entering the primary growth stage of the reactor. The use of a separate seed generation stage would be preferable to the single-stage reactor for particle growth by vapor deposition.
Designing Enterprise Applications with the J2EE¿ Platform (2002)

As part of the highly regarded Java BluePrints program, Designing Enterprise Applications with the J2EE Platform , Second Edition, describes the key architectural and design issues in applications supported by the J2EE platform and offers practical guidelines for both architects and developers. It explores key J2EE platform features such as Java servlets, JavaServer Pages, and Enterprise JavaBeans component models, as well as the JDBC API, Java Message Service API, and J2EE Connector Architecture. It also discusses security, deployment, transaction management, internationalization, and other important issues for today's applications.
THE VOCATIONAL REHABILITATION COUNSELOR IN THE TEAM APPROACH TO EXERCISE CENTERED CARDIAC REHABILITATION (1984)

Kostelac, J. M.; Adams, G. E. FACSM; Marlon, A. M.; Quinn, E. J.; Kaufman, J. A. Author Information
Mechanism of the stimulation of calcium ion dependent ATPase of cardiac sarcoplasmic reticulum by adenosine 3',5'-monophosphate dependent protein kinase (1980)

Canine cardiac sarcoplasmic reticulum (SR) is known to be phosphorylated by adenosine 3',5'-monophosphate (cAMP) dependent protein kinase on a 22 000-dalton protein. Phosphorylation enhances the initial rate of Ca2+ uptake and Ca2+-ATPase activity. To determine the molecular mechanism by which phosphorylation regulates the calcium pump in SR, we examined the effect of cAMP-dependent protein kinase on the individual steps of the Ca2+-ATPase reaction sequence. Cardiac sarcoplasmic reticulum was preincubated with cAMP and cAMP-dependent protein kinse in the presence (phosphorylated SR) and absence (control) of adenosine 5'-triphosphate (ATP). Control and phosphorylated SR were subsequently assayed for formation (4-200 ms) and decomposition (0-73 ms) of the acid-stable phosphorylated enzyme (E approximately P) of Ca2+-ATPase in media containing 100 microM [ATP] and various free [Ca2+]. cAMP-dependent phosphorylation of SR resulted in pronounced stimulation of initial rates and levels of E approximately P formed at low free [Ca2+] (less than or equal to 7 microM), but the effect was less at high free Ca2+ (greater than or equal to 10 microM). This stimulation was associated with a decrease in the dissociation constant for Ca2+ binding and a possible increase in Ca2+ sites. The observed rate constant for E approximately P formation of calcium-preincubated SR was not significantly altered by phosphorylation. Phosphorylation also increased the initial rate of E approximately P decomposition. These findings indicate that phosphorylation of cardiac SR by cAMP-dependent protein kinase regulates several steps in the Ca2+-ATPase reaction sequence which result in an overall stimulation of the calcium pump observed at steady state.
How to Leverage AI to Benefit the Chemical Industry (2021)

Abstract The chemical industry has at least as much to gain from applying AI tools as any other vertical, but it possesses its own unique challenges and obstacles that handicap the successful implementation of AI. Herein, the difficulties in applying AI to chemical plants are addressed and the importance of a cognitive layer is explained, which delivers context for AI tools and enables implementation.