gebhart/patrepeval huggingface dataset:
The System Identification and Predication of Carbon Migration in DMWS on High-temperature Based on ANN (2001)

In this paper,appling ANN to the non liner model and state identification of carbon diffusion of DMWS was consulted.The mothed of the BPNS studying algorithm of random iteration,Controlling network′s concussion of changeable step length,and selecting adaptive network structure of help network′s convergence were raised.Adaptive softwere was assembled as well and effective identification results were ganed thorugh emulating research.
Indium distribution and influence of internal fields in INGaN quantum wells (2018)

A detailed structural and optical characterisation of InGaN/GaN multiple quantum wells with In content up to 6% is presented. High resolution X-ray diffraction was employed to determine with a good accuracy the In content in the wells. The emission energy in the high injection limit confirmed the quantum confinement in the wells. In comparison with other III-V compounds the presence of a large spontaneous and strain induced polarisation generates strong electric fields in the wells. These fields are responsible of the quantum confined Stark effect, depending on the well thickness and In content, leading to a large red shift of the transition energies with respect to the energy gap of the material. The chapter presents a detailed structural and optical characterisation of InGaN/GaN quantum wells by means of the complementary use of high resolution X-ray diffraction, transmission electron microscopy and cathodoluminescence techniques.
“섹스 앤 더 시티”: 섹슈얼리티, 몸, 쾌락에 대한 아우구스티누스의 관점 다시 읽기 (2013)

아우구스티누스는 섹슈얼리티, 몸, 욕망, 쾌락에 대한 서구 그리스도교의 부정적이 고 억압적 전통의 원천으로 주로 비판을 받아 왔다. 그러나 후기 고대 엘리트들의 금욕주의 풍토와 초기 그리스도교의 급진적이고 반사회적인 동정의 열정, 4세기 이후 요비 니아누스가 촉발시킨 금욕과 결혼의 영적 위계에 대한 논쟁, 펠라기우스/율리아누스 논쟁 등을 배경으로 아우구스티누스의 저작들을 꼼꼼히 검토해보면, 상당히 다른 측면과 그의 유산의 복합성을 발견할 수 있다. 아우구스티누스의 신학적 작업은 그리스도교가 반사회적 소수 종교로부터 공인 이 후 주류 사회와 통합되기 시작한 4, 5세기를 배경으로 한다. 그리스도교의 금욕적 실천 에서 종말론적 열의와 강한 자유의 함축이 뒷전으로 밀려나고 영적 위계 문제를 통해 성스러움을 재편함으로써 적극적으로 보편적 교회의 질서를 구축하려는 과정이 전면에 대두되던 시대였다. 그런 상황에서 아우구스티누스는 금욕적 이상과 결혼의 선함을 이분 법적으로 보는 당시 논쟁의 어느 한 편에 서지 않고, 개개인의 동정의 덕을 특권화하거 나결혼(의 섹슈얼리티)에 온전한 거룩함을 부여하기보다 구원의 은총을 독점한 보편 교회의 교권을 수호하는 방향으로 역설적인 중도의 신학을 전개했다. 아우구스티누스는 결혼의 유익함을 인정하지만 결혼의 섹슈얼리티를 결코 신비화 하지 않았으며, 결혼보다 동정의 영적 우위를 인정하지만 동정녀나 금욕 수도자조차 원 죄의 징후인 정욕으로부터 스스로 자유로울 수 없다고 주장하며 금욕의 특권화를 경계 했고, 정욕과 섹슈얼리티를 원죄와 관련하여 부정적으로 규정하지만 결혼의 정욕과 육 체의 정욕을 구별하면서 죄에 물든 육체의 정욕과 다른 무죄한 정욕의 가능성을 시사하기도 했다. 섹슈얼리티와 쾌락을 벗어야 할 죄의 몸에 할당하지만, 성차와 감각, 감정, 욕망을 가지며 섹슈얼리티의 가능성도 배제되지 않는 부활의 몸에 대한 확고한 믿음은 섹슈얼리티와 몸, 쾌락에 대한 아우구스티누스 신학의 양가적 태도와 복합적 성격을 잘 보여 준다. 결론적으로 볼 때 아우구스티누스는 몸과 욕망, 감각, 감각적 쾌락 자체를 부정함 으로써 극복하려한 당대의 이원론적 금욕주의가 아니라, 그것을 죄와 구원의 역설적 거 점으로 보는 그리스도교 신학을 정초했다. 구원을 필요로 하는 인간실존을 영속적 죄의 식과 불안의 대상, 즉 죄의 몸으로 간주하여 부정적이고 억압적인 관점을 확립했지만, 구원의 비전 속에 온전한 기쁨, 진정한 쾌락과 함께 도래할 부활의 몸을 염원함으로써 섹슈얼리티와 몸, 쾌락의 존재론적 의미를 긍정하고 역설적으로 그리스도교 문화의 지 속적 관심사, 중요한 초점이 되게 한 복합적인 유산을 남겨주었다고 할 수 있다.
Markedly inhibited 7-dehydrocholesterol-delta 7-reductase activity in liver microsomes from Smith-Lemli-Opitz homozygotes. (1995)

We investigated the enzyme defect in late cholesterol biosynthesis in the Smith-Lemli-Opitz syndrome, a recessively inherited developmental disorder characterized by facial dysmorphism, mental retardation, and multiple organ congenital anomalies. Reduced plasma and tissue cholesterol with increased 7-dehydrocholesterol concentrations are biochemical features diagnostic of the inherited enzyme defect. Using isotope incorporation assays, we measured the transformation of the precursors, [3 alpha- 3H]lathosterol and [1,2-3H]7-dehydrocholesterol into cholesterol by liver microsomes from seven controls and four Smith-Lemli-Opitz homozygous subjects. The introduction of the double bond in lathosterol at C-5[6] to form 7-dehydrocholesterol that is catalyzed by lathosterol-5-dehydrogenase was equally rapid in controls and homozygotes liver microsomes (120 +/- 8 vs 100 +/- 7 pmol/mg protein per min, P = NS). In distinction, the reduction of the double bond at C-7 [8] in 7-dehydrocholesterol to yield cholesterol catalyzed by 7-dehydrocholesterol-delta 7-reductase was nine times greater in controls than homozygotes microsomes (365 +/- 23 vs 40 +/- 4 pmol/mg protein per min, P < 0.0001). These results demonstrate that the pathway of lathosterol to cholesterol in human liver includes 7-dehydrocholesterol as a key intermediate. In Smith-Lemli-Opitz homozygotes, the transformation of 7-dehydrocholesterol to cholesterol by hepatic microsomes was blocked although 7-dehydrocholesterol was produced abundantly from lathosterol. Thus, lathosterol 5-dehydrogenase is equally active which indicates that homozygotes liver microsomes are viable. Accordingly, microsomal 7-dehydrocholesterol-delta 7-reductase is inherited abnormally in Smith-Lemli-Opitz homozygotes.
Ionic fluorinated surfactants as corrosion inhibitors for aluminium and zinc pigments (2000)

Aluminium- and zinc pigments corrode in aqueous media at pH 10 with evolution of hydrogen. This process can be inhibited by certain surfactants. An anionic phosphate and to a lesser extent, a phosphonate hydrophilic group can be effectively used for corrosion inhibition. A fluoroalkyl hydrophobic group improves the corrosion inhibiting effect more than the hydrocarbon hydrophobic group; the influence of the hydrophobic group of the surfactants is small in comparison with the influence of the hydrophilic group. The efficiency of the best fluorinated surfactants studied is not affected by paint binders added in excess, either on aluminium or on zinc pigment.
Association of mitogen-activated protein kinases with microtubules in mouse macrophages. (1996)

Taxol, a microtubule-binding diterpene, mimics many effects of lipopolysaccharide (LPS) on mouse macrophages. The LPS-mimetic effects of taxol appear to be under the same genetic control as responses to LPS itself. Thus we have postulated a role for microtubule-associated proteins (MAP) in the response of macrophages to LPS. Stimulation of macrophages by LPS quickly induces the activation of mitogen-activated protein kinases (MAPK). MAPK are generally considered cytosolic enzymes. Herein we report that much of the LPS-activatable pool of MAPK in primary mouse peritoneal macrophages is microtubule associated. By immunofluorescence, MAPK were localized to colchicine- and nocodazole-disruptible filaments. From both mouse brain and RAW 264.7 macrophages, MAPK could be coisolated with polymerized tubulin. Fractionation of primary macrophages into cytosol-, microfilament-, microtubule-, and intermediated filament-rich extracts revealed that approximately 10% of MAPK but none of MAPK kinase (MEK1A and MEK2) was microtubule bound. Exposure of macrophages to LPS did not change the proportion of MAPK bound to microtubules, but preferentially activated the microtubule-associated pool. These findings confirm the prediction that LPS activates a kinase bound to microtubules. Together with LPS-mimetic actions of taxol and the shared genetic control of responses to LPS and taxol, these results support the hypothesis that a major LPS-signaling pathway in mouse macrophages may involve activation of one or more microtubule-associated kinases.
Polymorphic Measurement Method of FeO Content of Sinter Based on Heterogeneous Features of Infrared Thermal Images (2021)

FeO content of sinter is an important indicator of the quality of sinter. Aiming to overcome the difficulty of detecting the FeO content of sinter in the sintering process in real-time, this paper proposes a polymorphic measurement method for sinter FeO content based on heterogeneous features of infrared thermal images. First, an infrared thermal imager is applied to capture the infrared thermal images of sinter cross section at the tail of the sintering machine, and key frame and region of interest extraction are adopted to reduce the data throughput. Then, the shallow features and deep features that are related to the FeO content are extracted based on the regions of interest. Next, a polymorphic mechanism model is established to obtain the preliminary FeO content, and the sinter quality is divided into three grades according to the preliminary FeO content. Finally, three intelligent models corresponding to the three sinter grades are established to achieve the FeO content prediction based on the extracted heterogeneous features. Results in a sintering plant show that the proposed method can measure the FeO content accurately and provide reliable FeO content data for sintering site.
Development of Creep-Resistant and Oxidation-Resistant Austenitic Stainless Steels for High Temperature Applications (2017)

Austenitic stainless steels are cost-effective materials for high-temperature applications if they have the oxidation and creep resistance to withstand prolonged exposure at such conditions. Since 1990, Oak Ridge National Laboratory (ORNL) has developed advanced austenitic stainless steels with creep resistance comparable to Ni-based superalloy 617 at 800–900°C based on specially designed “engineered microstructures” utilizing a microstructure/composition database derived from about 20 years of radiation effect data on steels. The wrought high temperature-ultrafine precipitate strengthened (HT-UPS) steels with outstanding creep resistance at 700–800°C were developed for supercritical boiler and superheater tubing for fossil power plants in the early 1990s, the cast CF8C-Plus steels were developed in 1999–2001 for land-based gas turbine casing and diesel engine exhaust manifold and turbocharger applications at 700–900°C, and, in 2015–2017, new Al-modified cast stainless steels with oxidation and creep resistance capabilities up to 950–1000°C were developed for automotive exhaust manifold and turbocharger applications. This article reviews and summarizes their development and their properties and applications.
Infectious salmon anaemia virus (2002)

Infectious salmon anaemia virus (ISAV) is a commercially important orthomyxovirus causing disease in farmed Atlantic salmon. The cumulative mortality in a net pen during an outbreak may vary from insignificant to more than 90%. The infection is spread by management activity such as well-boat traffic, but possibly also through contact with wild fish. In many of its aspects, including the structure of the virus particle and replication strategy, the ISAV is similar to the influenza viruses. Variations between ISAV and the influenza viruses can mostly be related to differences in the temperature at which replication occurs and the immune response of their respective host animals. ISAV shows both haemagglutinating and receptor-destroying activity. The variability of the ISAV haemagglutinin molecule is concentrated around a small domain close to the transmembrane region. The function of this variable region is unknown, but it may be related to a recent or ongoing crossing of a species barrier. Alignment studies based on genetic data indicate that the phylogenetic relationship to the influenza viruses is distant, and that ISAV therefore could possibly warrant a new genus within Orthomyxoviridae.
Effect of Monensin on Ruminal Gas and VFA Production of Wethers Fed High Roughage Ration (1982)

モネンシンの飼料添加が,粗飼料多給条件下のめん羊第一胃内容物のガス及びVFA産生像に及ぼす影響について検討した.注射筒2本と三方コックからなる簡便な培養装置を用い,これにフィステルから採取した第一胃内容物を四重ガーゼで〓過したものを培養液として注入して,39°Cで4時間培養し,その間に発生したガスとVFAについて,モネンシン添加期と無添加期の間で比較した.その結果,モネンシン添加飼料の給与時には,第一胃内容物の総ガス生成量,CO2生成量,CH4生成量が,無添加飼料給与時に比べ減少し,またその差はいずれも統計的に有意であった.VFA産生像については,酢酸が有意に減少しプロピオン酸が有意に増加したが,酪酸には明らかな差は認められなかった.またモネンシン添加のこうした効果は添加をした21日間持続し減退することがなかったが,添加を中止した7日後には認められなくなった.
A Comparison Among Nalbuphine, Meperidine, and Placebo for Treating Postanesthetic Shivering (1999)

We evaluated nalbuphine versus meperidine and saline for treating postanesthetic shivering. Our results demonstrate that both nalbuphine and meperidine provide a similar rapid and potent anti-shivering effect. Nalbuphine may be an alternative to meperidine for treating postanesthetic shivering.
Exercise training improves radiotherapy efficiency in a murine model of prostate cancer (2020)

Engaging in exercise while undergoing radiotherapy (RT) has been reported to be safe and achievable. The impact of exercise training (ET) on RT efficiency is however largely unknown. Our study aims to investigate the interactions between ET and RT on prostate cancer growth. Athymic mice received a subcutaneous injection of PPC-1 cells and were randomly assigned to either cancer control, cancer ET, cancer RT, or cancer RT combined with ET (CaRT-ET). Mice were sacrificed 24 days post-injection. All three intervention groups had reduced tumor size, the most important decrease being observed in CaRT-ET mice. Apoptotic marker cleaved caspase-3 was not modified by ET, but enhanced with RT. Importantly, this increase was the highest when the two strategies were combined. Furthermore, NK1.1 staining and gene expression of natural killer (NK) cell receptors Klrk1 and Il2rβ were not affected by ET alone but were increased with RT, this effect being potentiated when combined with ET. Overall, our study shows that (a) ET enhances RT efficiency by potentiating NK cell infiltration, and (b) while ET alone and ET combined with RT both reduce tumor growth, the mechanisms mediating these effects are different.
<title>Macroscopic multiphoton biomedical imaging using semiconductor saturable Bragg reflector mode-locked lasers</title> (1999)

We report on the development of practical and user friendly lasers for multiphoton imaging of biological material. The laser developed for the work is a laser diode pumped Cr:LiSAF source modelocked using a saturable Bragg reflector as the passive modelocking element. For this system we routinely obtain 100 fs pulses at a repetition rate 200 MHz with an average output power of 20 mW. The laser has a single operator control and is particularly suitable for use by non-laser specialists. We have used the source developed to image a range of biologically significant samples. The initial work has centered on the imaging of intact human dental tissue. The first two-photon images of dental tissue are reported showing the development of early dental disease from depths up to 500 micrometers into the tooth. These results demonstrate the detection of carious lesions before the more conventional techniques currently used by dental practitioners. Work on other living intact biological tissue is also reported, in particular plants containing a genetically bred fluorescent marker to enable the examination of complete and intact living plant tissue.
[Abnormal communications in acute bacterial endocarditis of the aortic valve]. (1982)

Abnormal communications acquired during acute aortic valve bacterial endocarditis are rare but serious complications. Seven cases are reported; between the left ventricle and right atrium (3 cases), the left and right ventricles (2 cases), the aorta and right atrium (I case) and the aorta and left atrium (I case). The usual causal organisms is a staphylococcus (4 out of 7). The diagnosis is suspected on the development of atrio-ventricular block, a parasystolic murmur and sudden severe cardiac failure, but can only be confirmed by catheterisation and angiocardiography (impractical in our patients because of their poor condition). Echocardiography is of great diagnostic value. Surgical cure involves a double approach aortotomy and opening the other chamber involved), with extensive excision of the infected tissues, closure of the perforation, reconstruction of the aortic ring and implantation of an aortic valve prosthesis. The extent of the anatomical lesions affects the choice of the mode of reparation. There was no operative mortality in our series but two patients have persistent diastolic murmurs due to perivalvular leaks. In one case, recurrent infection led to the implantation of an apico-aortic tube with a fatal outcome.
Refining diagnosis of Parkinson's disease with deep learning-based interpretation of dopamine transporter imaging (2017)

Dopaminergic degeneration is a pathologic hallmark of Parkinson's disease (PD), which can be assessed by dopamine transporter imaging such as FP-CIT SPECT. Until now, imaging has been routinely interpreted by human though it can show interobserver variability and result in inconsistent diagnosis. In this study, we developed a deep learning-based FP-CIT SPECT interpretation system to refine the imaging diagnosis of Parkinson's disease. This system trained by SPECT images of PD patients and normal controls shows high classification accuracy comparable with the experts' evaluation referring quantification results. Its high accuracy was validated in an independent cohort composed of patients with PD and nonparkinsonian tremor. In addition, we showed that some patients clinically diagnosed as PD who have scans without evidence of dopaminergic deficit (SWEDD), an atypical subgroup of PD, could be reclassified by our automated system. Our results suggested that the deep learning-based model could accurately interpret FP-CIT SPECT and overcome variability of human evaluation. It could help imaging diagnosis of patients with uncertain Parkinsonism and provide objective patient group classification, particularly for SWEDD, in further clinical studies.
Neutral solvolysis of covalent arylsulfonylmethyl perchlorates. The kinetic basicity of water and some aliphatic alcohols (1977)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNeutral solvolysis of covalent arylsulfonylmethyl perchlorates. The kinetic basicity of water and some aliphatic alcoholsLubbertus Menninga and Jan B. F. N. EngbertsCite this: J. Org. Chem. 1977, 42, 16, 2694–2697Publication Date (Print):August 1, 1977Publication History Published online1 May 2002Published inissue 1 August 1977https://pubs.acs.org/doi/10.1021/jo00436a008https://doi.org/10.1021/jo00436a008research-articleACS PublicationsRequest reuse permissionsArticle Views27Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Impact of a Genetic Risk Score for Coronary Artery Disease on Reducing Cardiovascular Risk: A Pilot Randomized Controlled Study (2017)

Adding GRS to standard-of-care did not change lipids, adherence, or psychological outcomes. Potential modest benefits in weight loss and physical activity for participants with high GRS need to be validated in larger trials.
Filtration of Real-World Particles in Liquids by Microporous Membrane Filters (1995)

The filtration effect of irregular-shaped, real-world particles, such as silicon, alumina, and silicon nitride particles, has been experimentally investigated using 0.1, 0.22, and 0.45-μm-rated polyvinylidence difluoride (PVDF) and 0.2-μm polytetrafluoroethylene (PTFE) membrane filters. Particle retention tests were performed by measuring particle concentrations upstream and downstream of the test filter using an automatic liquid-borne laser particle counter (LPC). The test apparatus for the particle retention studies used a pump-driven water recirculating system. Zeta potential values play an important role in liquid filtration. The higher-charged particles, such as PSL and silicon, degraded filter efficiency during filter loading, while the lower-charged alumina and silicon nitride particles achieved complete retention over the entire range of test particle size, i.e., from 0.1 μm to 0.4 μm. Experimental results showed that if the filter and contaminant particles had a high charge of similar polarity, the electric double layers would interact in a repulsive manner, making the adsorptive deposition of the particle unfavorable and leaving sieving as the active filtration mechanism. If the contaminants had a low charge, they coagulated due to colloidal instability and were easily retained on the pore surfaces.
Not for the timid (2016)

To lower hosting costs and service prices, database-as-a-service (DBaaS) providers strive to maximize cluster utilization without negatively affecting their users' service experience. Some of the most effective approaches for increasing service efficiency result in the over-booking of the cluster with user databases. For instance, one approach is to reclaim cluster capacity from a database when it is idle, temporarily re-using the capacity for some other purpose, and over-booking the cluster's resources. Such approaches are largely driven by policies that determine when it is prudent to temporarily reclaim capacity from an idle database. In this paper, we examine policies that inherently tune the system's idle sensitivity. Increased sensitivity to idleness leads to aggressive over-booking while the converse leads to conservative reclamation and lower utilization levels. Aggressive over-booking also incurs a "reserve" capacity cost (for when we suddenly "owe" capacity to previously idle databases.) We answer these key questions in this paper: (1) how to find a "good" resource reclamation policy for a given DBaaS cluster of users; and (2) how to forecast the needed near-term reserve capacity. To help us answer these questions, we used production user activity traces from Azure SQL DB and built models of an over-booking mechanism. We show that choosing the right policy can substantially boost the efficiency of the service, facilitating lower service prices via lower amortized infrastructure costs.
Expression of neuronal nitric oxide synthase in the hippocampal formation in affective disorders (2008)

Hippocampal output is increased in affective disorders and is mediated by increased glutamatergic input via N-methyl-D-aspartate (NMDA) receptor and moderated by antidepressant treatment. Activation of NMDA receptors by glutamate evokes the release of nitric oxide (NO) by the activation of neuronal nitric oxide synthase (nNOS). The human hippocampus contains a high density of NMDA receptors and nNOS-expressing neurons suggesting the existence of an NMDA-NO transduction pathway which can be involved in the pathogenesis of affective disorders. We tested the hypothesis that nNOS expression is increased in the human hippocampus from affectively ill patients. Immunocytochemistry was used to demonstrate nNOS-expressing neurons in sections obtained from the Stanley Consortium postmortem brain collection from patients with major depression (MD, N = 15), bipolar disorder (BD, N = 15), and schizophrenia (N = 15) and from controls (N = 15). nNOS-immunoreactive (nNOS-IR) and Nissl-stained neurons were counted in entorhinal cortex, hippocampal CA1, CA2, CA3, and CA4 subfields, and subiculum. The numbers of Nissl-stained neurons were very similar in different diagnostic groups and correlated significantly with the number of nNOS-IR neurons. Both the MD and the BD groups had greater number of nNOS-IR neurons/400 microm(2) in CA1 (mean +/- SEM: MD = 9.2 +/- 0.6 and BD = 8.4 +/- 0.6) and subiculum (BD = 6.7 +/- 0.4) when compared to control group (6.6 +/- 0.5) and this was significantly more marked in samples from the right hemisphere. These changes were specific to affective disorders since no changes were seen in the schizophrenic group (6.7 +/- 0.8). The results support the current view of the NMDA-NO pathway as a target for the pathophysiology of affective disorders and antidepressant drug development.