gebhart/patrepeval huggingface dataset:
18.2: Bistable FLCOS Devices for Doubled‐Brightness Micro‐Projectors (2008)

Abstract Optical efficiency is of paramount importance to emerging ultra‐miniature projector products. We have developed experimental bistable ferroelectric‐liquid‐crystal‐on‐Silicon (FLCOS) projection microdisplay devices using newly developed FLC materials aligned on obliquely‐deposited SiO 2 . These devices enable doubling of illumination duty cycle, and hence doubling of achievable projector light output, while maintaining DC‐balanced electrical drive.
Spectral characterization of a self-Q-switched phase-conjugate Nd:YAG oscillator (1986)

There has recently been considerable interest in phase-conjugate oscillators (PCOs). In particular, several Nd:YAG-based pulsed configurations have been reported in which a stimulated Brillouin scattering cell functioned as the phase-conjugate mirror.1–3 Preliminary experiments in our laboratory have indicated that such a PCO is essentially as efficient as a conventional oscillator. This is somewhat surprising in view of speculations4 that accumulated SBS shifts might prematurely terminate the lasing process by walking the radiation out of the Nd:YAG gain bandwidth. One possible explanation is that some other stimulated scattering process having a smaller frequency shift5 might be operating, thereby eliminating any significant frequency walk-off. To clarify this matter, we investigated the spectrum of such a PCO, presenting here what is to our knowledge the first quantitative data showing Brillouin-shifted sidelobes on a broadened6 phase-conjugate resonator spectrum.
On Cycles of Sedimentation in the Eocene Strata of the Anglo-Franco-Belgian Basin (1921)

Landenian .—The Landenian is represented by the Thanet Sands and Woolwich and Reading Beds. The former seem to correspond to the two lower zones of the French Landenian, whilst the marine Bottom Bed of the Woolwich Series corresponds to the zone of Cyprina scutellaria . The present writer. has given reasons for believing the pebble-bed separating the two to be due to a movement of uplift in the Wealden area. 1 In the east of the London district the marine Bottom Bed passes up into clays and marls crowded with estuarine fossils (Woolwich Beds); to the west into unfossiliferous mottled clays and fluviatile sands (Reading Beds). The extensive transgression at the time of the zone of Cyprina scutellaria is noticeable in the London Basin as it is in the Paris and Hampshire Basins.
Lanthanide-induced shifts in 1H nuclear magnetic resonance: the significance of the angle term in the geometric factor of pseudocontact shift (1971)

A computer program is used to determine the position of the lanthanide ion which maximizes the correlation between the induced shift and the geometric factor (3 cos2θ–1)r–3; its use to demonstrate the significance of the angle term and in conformational analysis is described.
Effect of Surface Morphology on the On-State Resistance of SiC Photoconductive Semiconductor Switches (2012)

The photoconductive semiconductor switches (PCSS) were fabricated on V-doped semi-insulating 6H-SiC. We studied the effect of surface morphology on the on-state resistance of SiC PCSS. The SiC wafers with quite similar physical properties were processed by mechanical polishing, chemical mechanical polishing and H2 etching for producing different surface morphologies. All the SiC PCSS were excited by a 355 nm laser with a frequency of 10 Hz and a pulse intensity of 132 μJ/mm 2 . We found that the surface morphology had an obvious effect on the on-state resistance. The PCSS fabricated on mechanical polished SiC wafer with an average surface roughness (rms) of 1.0 nm showed the largest on-state resistance of 45.6 ohms, while a low value of 13.3 ohms was observed for the wafer processed by H2 etching at high temperature of 1550 °C.
Immunochemical characterization and localization of nitrate reductase in norflurazon‐treated soybean cotyledons (1984)

Immunochemical procedures were used to characterize and localize NADH:nitrate reductase (NR; EC 1.6.6.1) in cotyledons of norflurazon‐treated soybeans [ Glycine max (L.) Merr. cv. ‘Hill’]. Antiserum prepared to NR isolated from Chlorella strongly reacted against NR from norflurazon‐treated cotyledons. This serum inhibited the NR activity in crude extracts of norflurazon‐treated soybean cotyledons by 98% even at a 1:2000 dilution of crude serum. Pre‐immune serum had no effect on the activity. These data indicate that there are similar antigenic determinants at the active site of both Chlorella and norflurazon‐treated soybean NR. Whole cotyledons were homogenized in lithium dodecyl sulfate‐containing buffer, electrophoretically separated and blotted to nitrocellulose. When the blots were reacted with the anti‐NR serum only a single protein (M r = 98 kdalton) was visualized. Immunofluorescence studies on fixed tissue sections revealed intense fluorescence in the cytoplasm. Weaker reactions were associated with organelles tentatively identified as plastids. Pre‐immune serum controls were completely unstained using immunocytochemical procedures.
Effect of Small Nb‐doping Amount on the Performance of BaCoO 3‐δ ‐based Perovskite as Bifunctional Oxygen Catalysts (2018)

Abstract Perovskite oxides are of great interest as cost‐effective replacements for noble metals and oxides employed in bifunctional electrocatalysts including the oxygen reduction reaction (ORR) and oxygen evolution reaction (OER). In this work, a series of Bi/Nb co‐doped BaCoO 3‐δ ‐based perovskite oxides BaBi 0.05 Co 0.95‐x Nb x O 3‐δ (BBC 0.95‐x N x , x=0.1, 0.15, 0.2) were synthesized and evaluated as oxygen electrocatalysts for ORR and OER. It is interesting to note that Nb‐doping amount is related to the contents of surface oxygen vacancies and oxidation states of cobalt, subsequently inducing performance differences among BBC 0.95‐x N x . Results show that BBC 0.95‐x N x have bifunctional electrocatalytic activities toward both ORR and OER in alkaline media. Compared with the BBC 0.85 N 0.1 and BBC 0.8 N 0.15 , BBC 0.75 N 0.2 with the highest Nb‐doping rate delivered a lowest total overpotential between the ORR and the OER. Moreover, the BBC 0.95‐x N x catalysts deliver outstanding durability and methanol tolerance for ORR, better than Pt/C. BBC 0.95‐x N x holding promising application as nonprecious bifunctional catalysts.
Role of STAT3 in inflammatory bowel disease (2008)

抄写 3 的信号变换器和使活跃之物(STAT3 ) 包括煽动性的肠疾病(IBD ) 在各种各样的自体免疫的混乱起一个重要作用。最近的研究表明了 STAT3 激活起在天生的有免疫力的回答之间的显然不同的作用并且在大肠炎获得了有免疫力的回答。获得的有免疫力的回答的调停 STAT3 的激活由提高病原的 T 房间的幸存在大肠炎起一个病原的作用。相反，天生的回答的调停 STAT3 的激活贡献大肠炎的抑制。这评论将在 IBD 和为 IBD 的处理指向 STAT3 的潜力总结 STAT3 的角色的当前的理解，强调最近的观察。
Chemistry of Gliotoxins and their Derivatives (2022)

Bafana Radebe, Jeremiah Senabe*, Amos Kekae, Blessed Okole and Nomusa Dlamini Author Affiliations Council for Scientific and Industrial Research (CSIR), Advanced Agriculture and Food Cluster, South Africa Received: June 21, 2022 | Published: July 01, 2022 Corresponding author: Jeremiah Senabe, Council for Scientific and Industrial Research (CSIR), Advanced Agriculture and Food Cluster, P.O. Box 395, Pretoria, 0001, South Africa DOI: 10.26717/BJSTR.2022.44.007124
Adjuvant vaccination with melanoma antigen pulsed dendritic cells (DCs) in stage III melanoma patients (2009)

9039 Background: This is a pilot study evaluating of high-risk melanoma patients (pts) treated with peptide-DC vaccine after lymphadenectomy (LND). DC vaccination was designed to induce the immune response against melanoma antigens in melanoma pts who remain at high risk of dissemination after LND. Methods: DCs were generated from the bone marrow with the use GM-CSF, SCF, FLT3-L and TNFa or from peripheral blood adherent monocytes with GM-CSF and IL-4. DCs pulsed with HLA-A2-binding TYR, MART-1 and gp100 peptides and/or HLA-A1-binding MAGE-1, MAGE-3 peptides, tumor lysate if available, or with tracer antigen keyhole limpet hemocyanin (KLH), were injected sc 9 times within 8 months (mos). Boost injections were performed after 12 and 24 mos. Vaccinated pts were matched to unvaccinated controls (22 of 587) by sex, number of metastatic lymph nodes, extracapsular involvement, completion or therapeutic LND, Breslow stage (T), and ulceration. Results: HLA-A2 + , -A1 + or -A3 + melanoma pts (n=22), stage III, N1b-N3, enrolled between Sept. 2002 and Apr. 2004, received 5–16 vaccinations (median: 11) within 2 yrs. Cutaneous delayed type hypersensitivity (DTH) to melanoma peptides was induced in 12 of 22 pts. Peptide-specific IFNg producing CD8 + cells were detected in peripheral blood of 13 of 19 pts after vaccination. At least one of these responses to melanoma antigens was elicited in 17 of 22 pts. DTH to KLH was positive in 15 of 22 pts. Nine vaccinated pts are free of disease, and 1 is stable by Dec. 2008 (follow up is 58–76 mos after LND). Survival analysis for vaccinated pts and matched controls is presented in the Table . Conclusions: The DC/peptide vaccine elicited immune responses to melanoma antigens. Vaccinated pts had clinically substantially longer overall survival (OS) and disease free survival (DFS) than matched control. OS was associated with the immune responsiveness to melanoma antigens and to KLH. [Table: see text] No significant financial relationships to disclose.
Biominerals—hierarchical nanocomposites: the example of bone (2010)

Many organisms incorporate inorganic solids in their tissues to enhance their functional, primarily mechanical, properties. These mineralized tissues, also called biominerals, are unique organo-mineral nanocomposites, organized at several hierarchical levels, from nano- to macroscale. Unlike man-made composite materials, which often are simple physical blends of their components, the organic and inorganic phases in biominerals interface at the molecular level. Although these tissues are made of relatively weak components under ambient conditions, their hierarchical structural organization and intimate interactions between different elements lead to superior mechanical properties. Understanding basic principles of formation, structure, and functional properties of these tissues might lead to novel bioinspired strategies for material design and better treatments for diseases of the mineralized tissues. This review focuses on general principles of structural organization, formation, and functional properties of biominerals on the example the bone tissues.
Chitosan Feasibility to Retain Retinal Stem Cell Phenotype and Slow Proliferation for Retinal Transplantation (2014)

Retinal stem cells (RSCs) are promising in cell replacement strategies for retinal diseases. RSCs can migrate, differentiate, and integrate into retina. However, RSCs transplantation needs an adequate support; chitosan membrane (ChM) could be one, which can carry RSCs with high feasibility to support their integration into retina. RSCs were isolated, evaluated for phenotype, and subsequently grown on sterilized ChM and polystyrene surface for 8 hours, 1, 4, and 11 days for analysing cell adhesion, proliferation, viability, and phenotype. Isolated RSCs expressed GFAP, PKC, isolectin, recoverin, RPE65, PAX-6, cytokeratin 8/18, and nestin proteins. They adhered (28 ± 16%, 8 hours) and proliferated (40 ± 20 cells/field, day 1 and 244 ± 100 cells/field, day 4) significantly low (P < 0.05) on ChM. However, they maintained similar viability (>95%) and phenotype (cytokeratin 8/18, PAX6, and nestin proteins expression, day 11) on both surfaces (ChM and polystyrene). RSCs did not express alpha-SMA protein on both surfaces. RSCs express proteins belonging to epithelial, glial, and neural cells, confirming that they need further stimulus to reach a final destination of differentiation that could be provided in in vivo condition. ChM does not alternate RSCs behaviour and therefore can be used as a cell carrier so that slow proliferating RSCs can migrate and integrate into retina.
Relativistic Causal Ordering A Memory Model for Scalable Concurrent Data Structures (2000)

High-performance programs and systems require concurrency to take full advantage of available hardware. However, the available concurrent programming models force a difficult choice, between simple models such as mutual exclusion that produce little to no concurrency, or complex models such as Read-Copy Update that can scale to all available resources. Simple concurrent programming models enforce atomicity and causality, and this enforcement limits concurrency. Scalable concurrent programming models expose the weakly ordered hardware memory model, requiring careful and explicit enforcement of causality to preserve correctness, as demonstrated in this dissertation through the manual construction of a scalable hash-table item-move algorithm. Recent research on "relativistic programming" aims to standardize the programming model of Read-Copy Update, but thus far these efforts have lacked a generalized memory ordering model, requiring data-structure-specific reasoning to preserve causality. I propose a new memory ordering model, "relativistic causal ordering", which combines the scalabilty of relativistic programming and Read-Copy Update with the simplicity of reader atomicity and automatic enforcement of causality. Programs written for the relativistic model translate to scalable concurrent programs for weakly-ordered hardware via a mechanical process of inserting barrier operations according to well-defined rules. To demonstrate the relativistic causal ordering model, I walk through the straightforward construction of a novel concurrent hash-table resize algorithm, including the translation of this algorithm from the relativistic model to a hardware memory model, and show through benchmarks that the resulting algorithm scales far better than those based on mutual exclusion.
Steric effects in the hydrolysis of methyl- and tert-butylphenylphosphinic chloride and fluoride (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSteric effects in the hydrolysis of methyl- and tert-butylphenylphosphinic chloride and fluorideRichard J. Brooks and Clifford A. BuntonCite this: J. Org. Chem. 1975, 40, 14, 2059–2064Publication Date (Print):July 1, 1975Publication History Published online1 May 2002Published inissue 1 July 1975https://pubs.acs.org/doi/10.1021/jo00902a011https://doi.org/10.1021/jo00902a011research-articleACS PublicationsRequest reuse permissionsArticle Views83Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Photo Quiz: Is Gardening Dangerous? (2017)

A 60-year-old female without any notable past medical or surgical history presented with redness, swelling, and pain at the base of her left fourth finger. Twelve hours before, she had cut the end of her finger with the tip of a pitchfork while mixing the compost in her garden. At the time of
Aberrant multimeric structure of von Willebrand factor in a new variant of von Willebrand's disease (type IIC). (1982)

A variant of von Willebrand's disease has been identified in which sodium dodecyl sulfate agarose electrophoresis provides evidence that the von Willebrand factor present is structurally abnormal. Rather than the repeating triplet seen in normal subjects and in patients with the IIA and IIB variants, a repeating doublet was present in the propositus. None of the bands had the same mobility as bands in normal subjects or previously described von Willebrand's disease patients. The larger multimers of von Willebrand factor were lacking both from plasma and platelets, and did not appear in the circulation after infusion of 1-deamino-[8-D-arginine]-vasopressin. There was a marked increase in the concentration of the smallest multimer in the propositus and his phenotypically normal children, indicating that this abnormality of von Willebrand factor is inherited in an autosomal-recessive manner.
Gaining Insight into Off-Target Mediated Effects of Drug Candidates with a Comprehensive Systems Chemical Biology Analysis (2009)

We present a workflow that leverages data from chemogenomics based target predictions with Systems Biology databases to better understand off-target related toxicities. By analyzing a set of compounds that share a common toxic phenotype and by comparing the pathways they affect with pathways modulated by nontoxic compounds we are able to establish links between pathways and particular adverse effects. We further link these predictive results with literature data in order to explain why a certain pathway is predicted. Specifically, relevant pathways are elucidated for the side effects rhabdomyolysis and hypotension. Prospectively, our approach is valuable not only to better understand toxicities of novel compounds early on but also for drug repurposing exercises to find novel uses for known drugs.
Predictions of Flow Boiling in Fractal-Like Branching Microchannels (2005)

Single-phase and two-phase flows in microscale fractal-like branching flow networks are studied using a one-dimensional model that includes variable property and developing flow effects. Pressure drop, pumping power, changes in the bulk fluid temperature and a performance parameter are reported for mass flow rates ranging from 25 to 500 g/min and wall heat fluxes from 5 to 40 W/cm2. Two-phase flow through fractal-like flow networks is also compared to flow through a series of parallel channels for identical wall heat fluxes and for flow rates between 25 and 100 g/min. Channel length, height, convective surface area, heat flux and flow rate were the same between the fractal-like and parallel channel array. It was found that single-phase flows through fractal-like flow networks exhibit lower pressure drop and pumping power than do two-phase flows at the same wall heat flux and mass flow rate. The inlet temperature for the single-phase cases is 20°C, whereas the two-phase flow enters as a saturated liquid. The pressure drop and pumping power were always lowest for the fractal-like flow networks compared with the parallel channel arrays for identical heat transfer and flow rates.
Confirmation of the efficacy of ERr 731 in perimenopausal women with menopausal symptoms. (2009)

ERr 731 was confirmed to be effective for the treatment of menopausal symptoms in perimenopause.
REVERSING GOES BROADBAND (2004)

A recent HSE report states that a major category of accident is the 'slow-moving-vehicle reversing accident' particularly involving forklift and other lift-truck vehicles. It is important that a vehicle's reversing alarm should be well designed. There are two types of reversing alarm: conventional alarms (based on a single frequency) and broadband sound alarms that use a multifrequency range. There are three issues for reversing alarms: the ability to alert a listener, the locatability of the sound and the impact of the sound on perceived noise nuisance. Conventional and broadband alarms are compared with respect to these issues. A broadband reversing alarm is as effective at alerting the listener at approximately 5dB(A) less than a conventional alarm and is little heard either in front of or to the sides of the vehicle. The physical and psychoacoustic principles underlying these effects are outlined. The results of a field survey involving 1,477 vehicles fitted with reversing alarms are presented.
Effect of replacing dried skim milk with specially processed soy products on digestibility of nutrients and growth performance of nursery pigs (1990)

One hundred twenty-eight pigs (21 d of age and 11.7 lb) were used to determine the effects of feeding specially processed soy products and lactose versus dried skim milk on growth performance and nutrient digestibility. For d 0-14, pigs received pelleted diets that were: 1) corn-soybean meal-whey control; 2) a high nutrient density diet (HNDD) containing 20% dried skim milk and 20% dried whey; 3 and 4) the HNDD with soy protein isolate replacing 50% and 100% of the protein supplied by dried skim milk; 5 and 6) the HNDD with soy protein concentrate replacing 50% and 100% of the protein supplied by dried skim milk; 7 and 8) the HNDD with modified soy flour replacing 50% and 100% of the protein supplied by dried skim milk. For d 14-35, all pigs were fed a common diet. Average daily gain (ADG), average daily feed intake (ADFI), feed:gain ratio (F/G), and fecal scores were determined for d 7, 14, and 35 of the experiment. Apparent digestibilities of N and DM were determined from fecal samples collected on d 13. For d 0 to 7, pigs fed the HNDD had the best F/G, pigs fed the corn-soybean meal-whey control had the poorest F/G, and pigs fed diets with the specially processed soy products were intermediate in feed efficiency. Pigs fed the soy isolate had improved feed efficiency and less incidence of diarrhea compared to pigs fed the soy concentrate. For d 0 to 14, pigs fed the corn-soybean meal-whey control had the poorest performance and DM digestibility. When dried skim milk was replaced with the specially processed soy products, F/G was worse, but digestibility of N and DM were not decreased, especially at the 50% level of replacement. Pigs fed the soy isolate had performance more similar to pigs fed the HNDD than pigs fed the soy concentrate or modified soy flour. From d 0 to 35, ADG and ADFI were greater for pigs fed diets with soy products replacing the protein from dried skim milk than pigs given the HNDD. However, pigs fed the HNDD gained more efficiently. Our data indicate that replacing the protein from dried skim milk with the specially processed soy products tested in this experiment resulted in slight depressions in performance early in the nursery phase (ie., d 0 to 14). However, as the processing techniques became more elaborate (ie., isolate> concentrate> modified soy flour), utilization of
E-Governance in the Developing World in Action (2008)

E-Governance is a powerful tool for bringing about change to government processes in the developing world. E-governance operates at the cross roads between Information and Communication Technology and government processes, and can be divided into three overlapping domains: e-administration, e-services and e-society. In order to be successful, e-governance must be firmly embedded in the existing government processes, must be supported, both politically and technically, by the governments, and must provide users with reasons to use these on-line domains. In order to maximize the impact, process change needs to be considered part and parcel of e-governance.&#x0D; &#x0D; In this report, we present and evaluate an e-governance programme in the East African country of Uganda. The programme, DistrictNet, tries to provide transparency at the local government level and to improve the provision of public information through the implementation of ICT. DistrictNet started in 2002 and is on-going. The achievements of the programme are presented and evaluated according to the criteria of the three domains of e-governance and their impact on government processes. On the basis of this evaluation, we elicit lessons that can be used to guide similar programmes at the local government levels in the developing world. &#x0D;