gebhart/patrepeval huggingface dataset:
Separation of contour and area dependent components in the first and second order kernels of the multifocal pattern appearance evoked potential (2002)

The non-linearities of the diffuse flash visual evoked potential (VEP) have been shown to generate separable waves corresponding to Magnocellular and Parvocellular contributions. The authors wished to investigate whether, under conditions of isoluminance, the chromatic pattern appearance VEP shows waveforms that are related to both the processing of contours (the pattern) and the processing of the diffuse stimulation (from the area lying between the contours). The VERIS multifocal system was used to record monocular VEP. Standard 2-ring, 3-ring, 5-ring and 7-ring VERIS pattern stimuli were employed with a cardboard circular aperture used to blank the stimulus monitor to a 9-cm diameter field. The results for four subjects were recorded. The first order kernel responses showed a significant increase in amplitude with total contour length. In comparison, the amplitudes of the first and second slices of the second order kernel did not increase with contour length. It appears that the contour-dependent component has negligible non-linear components. It is proposed that the constant, non-zero responses of the higher order kernel components reflects contributions from the diffuse chromatic VEP.
Coalition formation processes with belief revision among bounded-rational self-interested agents (1999)

This paper studies coalition formation among self-interested agents that cannot make sidepayments. We show that α-core stability reduces to analysing whether some utility profile is maximal for all agents. We also show that strategy profiles that lead to the α-core are a subset of Strong Nash equilibria. This fact carries our α-core-based stability results directly over to two other strategic solution concepts: Nash equilibrium and Coalition-Proof Nash equilibrium. The main focus of the paper is to analyse the dynamic process of coalition formation by explicitly modelling the costs of communication and deliberation. We describe an algorithm for sequential action choice where each agent greedily stepwise maximizes its payoff given its beliefs. Conditions are derived under which this process leads to convergence of the agents' beliefs and to a stable coalition structure. We derive these results for the case where the length of the process is exogenously restricted as well as for the case where agents can choose it. Finally, we show that the outcome of any communication/deliberation process that leads to a stable coalition structure is Pareto-optimal for the original game which does not incorporate communication or deliberation. Conversely, any Pareto-optimal outcome can be supported by a communication/deliberation process that leads to a stable coalition structure.
Hb O-TIBESTI [β121(GH4)Glu → Lys; β11(A8)Val → Ile], A HEMOGLOBIN VARIANT CARRYING IN THE SAME β CHAIN THE SUBSTITUTIONS OF Hb O-ARAB AND Hb HAMILTON, FOUND IN COMBINATION WITH Hb S [β6(A3)Glu → Val] (2002)

Hb O-Tibesti, carries in the same chain the substitution of Hb O-Arab [beta121(GH4)Glu-->Lys] and that of Hb Hamilton [beta11(A8)Val-->Ile]. Hb O-Tibesti may be distinguished from Hb O-Arab by polyacrylamide gel electrophoresis in the presence of urea and Triton-X100, and by reversed phase high performance liquid chromatography. It was found in a compound heterozygous condition with Hb S [beta6(A3)Glu-->Val] in a child of Chad-Sudanese descent, suffering from a sickle cell syndrome. Compared to the classical description of the Hb S/Hb O-Arab association, the additional Hb Hamilton mutation does not seem to modify the clinical presentation.
AgNOR Count in Resting Cells (Resting NOR) Is a New Prognostic Marker in Invasive Bladder Tumor (2001)

Resting NOR had a predictive value in the prognosis of patients with invasive bladder tumor.
Predictive Poly Rib Belt Tracking (2004)

&lt;div class="htmlview paragraph"&gt;A geometrical set of closed form trigonometric equations are developed as a simplified alternative to the complex numerical computations required for determining lateral belt tracking locus due to pulley misalignment tolerances. Solutions are validated by a comprehensive statistically designed database. Further, analytical verification is obtained from ABAQUS/Explicit results based on a nonlinear hyperelastic Ogden finite element model.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;Three-dimensional geometric equations form the basis of a computer tool developed to predict belt displacement across a flat backside pulley, as well as angles of entering and exiting spans. Predictions are performed for the critical combination of a grooved-flat-grooved pulley arrangement typically found in automatically tensioned front-end automotive serpentine accessory drives.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;Excellent correlation is found between the three-dimensional finite element analysis, experimental data, and the simplified geometrical model. Consequently, accessory design engineers can effectively deploy the geometrical model to rapidly determine relationships between belt tracking and numerous critical drive parameters.&lt;/div&gt;
Analysis of an EST library from the dinoflagellate (Symbiodinium sp.) symbiont of reef‐building corals1 (2007)

Dinoflagellates ( Symbiodinium sp. Freud.) are an obligatory endosymbiont of the reef‐building corals. Recent changes to the environment surrounding coral reefs (e.g., global warming) have demonstrated that this endosymbiotic relationship between corals and Symbiodinium is particularly sensitive to environmental changes. Therefore, understanding gene expression patterns of Symbiodinium is critical to understanding why coral reefs are susceptible to global climate change. This study identified 1456 unique expression sequence tags (ESTs) generated for Symbiodinium (clade C3) from the staghorn coral Acropora aspera following exposure to a variety of stresses. Of these, only 10% matched previously reported dinoflagellate ESTs, suggesting that the conditions used in the construction of the library resulted in a novel transcriptome. The function of 561 (44%) of these ESTs could be identified. The majority of these genes coded for proteins involved in posttranslational modification, protein turnover, and chaperones (12.3%); energy production and conversion (12%); or an unknown function (18.6%). The most common transcript found was a homologue to a bacterial protein of unknown function. This algal protein is targeted to the chloroplast and is present in those phototrophs that acquired plastids from the red algal lineage. An additional 48 prokaryote‐like proteins were also identified, including the first glycerol‐phosphate:phosphate antiporter from dinoflagellates. A protein with similarity to the fungi–archael–bacterial heme catalase peroxidases was also found. A variety of stress genes, in particular heat‐shock proteins and proteins involved in ubiquitin cascades, were also identified. This study is the first transcriptome from the unicellular component of a eukaryote–eukaryote symbiosis.
National Institutes of Health Consensus Development Conference Statement on Diagnosis and Treatment of Early Melanoma, January 27–29, 1992 (1993)

The National Institutes of Health Consensus Development Conference on Diagnosis and Treatment of Early Melanoma brought together experts in dermatology, pathology, epidemiology, public education, surveillance techniques, and potential new technologies, as well as other health care professionals and the public, to address (a) the clinical and histological characteristics of early melanoma; (b) the appropriate diagnosis, management, and follow-up of patients with early melanoma; (c) the role of dysplastic nevi and their significance; and (d) the role of education and screening in preventing melanoma morbidity and mortality. Following 2 days of presentations by experts and discussion by the audience, a consensus panel weighted the evidence and prepared a consensus statement. The panel agreed (a) that melanoma in situ is a distinct entity that can be treated effectively by surgery with 0.5-cm margins and that thin, invasive melanoma < 1 mm thick has the potential for long-term survival in < 90% of patients after surgical excision with a 1-cm margin; (b) that elective lymph node dissections and extensive staging evaluations should not be recommended in early melanoma; (c) that patients with early melanoma are at low risk for relapse but may be at high risk for development of subsequent melanomas and therefore should be followed closely; (d) that some family members of patients with melanoma are at increased risk for melanoma and therefore should be enrolled in surveillance programs; and (e) that education and screening programs have the potential to decrease morbidity and mortality from melanoma. The full text of the consensus panel's statement follows.
Structural Characterization and Functional Analysis of the Follistatin Promoter of Larimichthys crocea (2016)

Follistatin is a secreted glycoprotein, which involved in numerous physiological activities as an antagonist of the transforming growth factor-β superfamily. However, little is known about the regulation mechanism of follistatin in fish. In this study we cloned and analyzed part of the 5' flanking region of the follistatin gene in Larimichthys crocea. Sequence analysis revealed several putative binding sites for transcription factors including activator protein 1 (AP1), myogenic differentiation factor (MyoD), stimulating protein 1 (SP1), and sex determining gene on the mammalian Y chromosome (SRY) in the cloned fragment. Transcriptional activities of two fragments (485 and 261 bp) truncated from follistatin upstream region were examined in vitro, using transient transfection in Ctenopharyngodon idella kidney (CIK) and Rattus norvegicus skeletal muscle myoblast (L6) cells. The result showed that the promoter activity correlated positively with the length of truncated fragments in both CIK and L6 cells. To study the regulation of follistatin expression in L. crocea, we cloned MyoD and SRY-box 8 (Sox8) genes and examined their action on the follistatin promoter by co-transfection in CIK and L6 cells. The results showed MyoD and Sox8 could suppress the activities of follistatin promoter at different levels in CIK and L6 cells.
A dsbA mutant of Pseudomonas syringae exhibits reduced virulence and partial impairment of type III secretion (2000)

Abstract To identify virulence genes of P. syringae pv. tomato strain DC3000 we screened for mutants with reduced virulence on its plant hosts, Arabidopsis thaliana and tomato. We isolated a Tn5-insertion mutant that exhibited reduced virulence on both hosts. Further characterization showed that this mutant carried a single Tn5 insertion in the dsbA gene, which encodes a periplasmic disulphide bond-forming protein. In addition to reduced virulence, the dsbA mutant exhibits mucoid colony morphology, loss of fluorescence, decreased motility, and a reduced growth rate in culture. The dsbA mutant is able to multiply in A. thaliana and tomato plants, trigger the hypersensitive response on tobacco and elicit Pto-mediated resistance in tomato, indicating that type III secretion occurs in this background. However, type III secretion appears to function with reduced efficiency in the dsbA mutant, as type III-dependent secretion of HrpZ and AvrRpt2 is impaired. These findings indicate that while the dsbA gene is required for multiple cellular functions in P. syringae, type III secretion in P. syringae is only partially dependent on dsbA.
Deubiquitinating enzyme USP46 suppresses the progression of hepatocellular carcinoma by stabilizing MST1 (2021)

The deubiquitinating enzyme USP46 (ubiquitin-specific protease 46) is implicated in various cancers. However, its role and regulatory mechanism in HCC (hepatocellular carcinoma) are still unknown. In this study, we showed that USP46 is downregulated in HCC tissues and that low USP46 levels are associated with poor prognosis in HCC patients. In functional experiments, overexpression of USP46 impaired proliferation and metastasis of HCC cells, whereas knockdown of USP46 enhanced cell proliferation and invasiveness in vitro and in vivo. Furthermore, we found that USP46 suppresses HCC cell proliferation and metastasis by inhibiting YAP1. Ectopic expression of YAP1 rescued the inhibition of cell proliferation and metastasis caused by USP46 overexpression. Mechanistically, USP46 promotes the degradation of YAP1 by increasing expression of MST1, and the increase in MST1 protein antagonizes YAP1 to suppress HCC progression. Finally, we demonstrated that USP46 stabilizes the MST1 protein by directly binding to it and decreasing its ubiquitination. Taken together, our results demonstrated that USP46 may be a novel tumor suppressor in HCC. Moreover, USP46 acts as a deubiquitinating enzyme of MST1 to potentiate MST1 kinase activity to suppress tumor growth and metastasis, indicating that USP46 activation may represent a potential treatment strategy for HCC.
Medical aspects of global warming (2001)

Warming can be demonstrated by the observed changes that have already occurred in the environment, particularly the thinning of polar ice caps. The United States Global Research Program has been established to coordinate research activities, which responds to issues deemed important by the United Nations Framework Convention on Climate Change. Research issues pertain to the scientific uncertainties in the greenhouse effect, temperature measurements at various atmospheric levels and latitudes, and impact on biota redistribution. The Kyoto Protocol has mandated specific solutions, e.g., a 7% reduction in CO2 levels within 10 years. Future recommendations involve supporting new technologies that are available to decrease emissions as well as understanding the role that occupational and environmental specialists have in global warming recognition.
Synthesis of Seven‐Membered Rings by [(σ2+π2)+π2] Cycloaddition to Homodienes (1985)

The cycloaddition of activated vinylcyclopropanes to dienophiles leads to seven-membered rings. This [(σ2+π2)+π2] cycloaddition is presumably the last, still incompletely investigated pericyclic six-center reaction with carbon atoms as reaction centers. Example: Homofuran 1 and homothiophene 2 react with tetracyanoethylene quantitatively in a few minutes at 25°C to give 3 and 4, respectively.
Alcohol Inhibits Smooth Muscle Cell Proliferation via Regulation of the Notch Signaling Pathway (2010)

EtOH inhibits Notch signaling and, subsequently, SMC proliferation, in vitro and in vivo. The modulation of Notch signaling in SMCs by EtOH may be relevant to the cardiovascular protective effects of moderate alcohol consumption purported by epidemiological studies.
Effects of Wet Etching on Photoluminescence of Porous Silicon (2000)

A room‐temperature wet process which allows control of the wavelength of photoluminescence from porous silicon has been developed. This process reduces the size of the silicon crystal by the repeated formation and removal of the surface oxide. It has been learned that the surface after this process does not have residual oxide. Synchrotron radiation photoemission spectroscopy and X‐ray absorption near edge structure measurements have revealed that the bandgap of porous silicon becomes wide with repetition of our wet process. © 2000 The Electrochemical Society. All rights reserved.
High brightness and efficiency blue light-emitting polymer diodes (1998)

Efficient blue electroluminescence, peaked at 436 nm, is demonstrated from polymer light-emitting diodes operating at high brightness. A dioctyl-substituted polyfluorene was used as the emissive layer in combination with a polymeric triphenyldiamine hole transport layer. The luminance reaches 600 cd/m2 at a current density of 150 mA/cm2 for a bias voltage of 20 V, corresponding to an efficiency of 0.25 cd/A and a luminosity of 0.04 lm/W. These values are optimized at a critical emissive layer thickness.
A flexible new method to improve the accuracy of SMA self-sensing control (2012)

This paper proposes a flexible new method to improve the accuracy of SMA(shape memory alloy) self-sensing control, especially in low load, and broaden the application condition of it. SMA is a kind of intelligent material, it can be acted as an actuator(have big output force ratio) and a sensor at the same time in control system. For these advantages, the SMA has a lot of applications. Since the control model of SMA varies with the change of control variables, the accuracy of the self-sensing control is not high enough, especially under low pretightening. In this paper, we constructed the control model of SMA by using two base models to work out the changeable control model. Compared with traditional control method which use only the base model under certain pretightening force, the proposed new method is easier to apply and has less limit on pretightening force, and the accuracy also improved a lot. The SMA actuator can be applied onto a lot of micro mechanism, such as artificial muscle, micro wrist, micro finger, so this improvement have significance in practical use.
The Evolution of Hip Arthroscopy: What Has Changed Since 2008—A Single Surgeon’s Experience (2020)

Level III, retrospective comparative trial.
Polytopic Modeling and Lyapunov Stability Analysis of Power Electronics Systems (2002)

&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;Power electronics based power distribution systems are inherently nonlinear often behaving as constant power loads. Stability analysis of such systems typically is limited to local behavior. Herein polytopic modeling techniques are presented. Classification of polytopic model equilibrium points is made and methods of determining uniform asymptotic stability are presented.&lt;/div&gt;&lt;/div&gt;
Hybrid Microporous Membranes Intended for Protective Clothing (2009)

Electrospun nanofiber containing titanium dioxides (TiO2) was investigated as a self-detoxifying system. The material system was developed using polyacrylonitrile(PAN)-metal oxide composite fibers containing anatase TiO2. Fibers were prepared by uniaxial and coaxial electrospinning to compare the detoxification activities of the photocatalyst in different fiber morphologies. Monoaxial nanofibers were formed by conventional electrospinning of PAN/DMF solution containing TiO2 nanoparticles, while coaxial nanofibers had the metal oxide selectively placed in the sheath layer by electrospinning pure PAN solution and PAN/TiO2 solution as core and sheath layer, respectively. Location of nanoparticles relative to fiber morphology was determined by SEM and TEM. It was demonstrated that the coaxial approach resulted in location of nanoparticles in the sheath of the fibers rather than the uniform distribution obtained for monoaxial fibers. Photocatalytic activity of the PAN/TiO2 fibers under UV irradiations was demonstrated by degradation of aldicarb, a carbamate pesticide, as measured by HPLC. In terms of degradation kinetics, surface distribution density of TiO2 nanoparticles on the electrospun fiber affected initial degradation rates while the final decomposition amounts did not differ for the submicron fibers.
ChemInform Abstract: Formation of Cyclopropylsulfones from 1‐Arylsulfonyl‐2‐ chloromethylprop‐2‐enes. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Effects on growth performance, feed efficiency, and health of weanling pigs fed fermented liquid whey inoculated with lactic acid bacteria that inhibit Escherichia coli in vitro (2007)

Objectives: To determine the fermentation dynamics of liquid whey-dextrose (FLWD) inoculated with lactic acid bacteria (LAB) and whether feeding FLWD inoculated with LAB and added to a basal dry diet without antibiotics affects growth, feed efficiency, and health of weanling pigs. Materials and methods: One hundred and forty newly weaned pigs were assigned to five dietary treatments (four pens of seven pigs per treatment). Three FLWD preparations inoculated with either human- or pig-origin LAB strains were added to a basal dry feed. The fourth FLWD preparation contained no LAB. The fifth diet was the basal dry feed containing 0.1% lincomycin (control). LAB strains were mixed with FLWD prior to fermentation. Dry matter (DM), pH, and LAB counts of diets were measured daily during the 5-day fermentation period and the first 2 days of storage. Growth performance was recorded and rectal swabs were collected weekly. Fecal consistency was evaluated daily. Results: The pH and DM of fermented feed decreased and total LAB increased over time. Average daily gain and feed intake were highest in controls. Prevalence and severity of diarrhea were greater in pigs consuming LAB-inoculated diets than in control pigs. Mortality did not differ among treatment groups. Fewer hemolytic Escherichia coli were recovered from pigs fed FLWD. Implications: Fermented liquid feeds do not consistently promote better growth performance and health in weanling pigs. Use of LAB in starter feed may inhibit enteric E coli; however, further studies are needed to determine whether specific strains of LAB may prevent postweaning diarrhea.
Combined DC voltage control scheme for three-port energy router based on instantaneous energy balance (2016)

DC voltage control is crucial for the multi-stage converter, because it contributes to reduce the DC capacitance and improve the reliability of the whole system. A combined control scheme, induding two parts, is proposed in this paper for controlling the two DC bus voltages respectively in the Energy Router. Firstly, the energy feed-forward control scheme is used to control the low voltage DC bus, which connects the dual active bridge, the inverter and the bidirectional DC/DC converter. Compared with the conventional feed-forward control scheme, the energy feed-forward control scheme considers the instantaneous energy changes of the inductors in the inverter and the DC/DC converter together. Secondly, for the high voltage DC bus, which is connected to the single-phase PWM rectifier, a new control scheme is proposed based on the energy balance relationship among the source, the load and the passive elements (the inductors and the capacitors). The proposed combined control scheme can improve obviously the transient performances of the two DC bus voltages. Simulation and experimental results have confirmed their superior performances.
An Iron-regulated Gene, magA, Encoding an Iron Transport Protein of Magnetospirillum sp. Strain AMB-1 (1995)

Magnetospirillum sp. AMB-1 is a freshwater magnetic bacterium which synthesizes intracellular particles of magnetite (Fe3O4). A genomic DNA fragment required for synthesis of magnetic particles was previously isolated from a nonmagnetic transposon Tn5 mutant. We have determined the complete nucleotide sequence of this fragment. The 2975-base pair region contains two putative open reading frames. One open reading frame, designated magA, encodes a polypeptide which is homologous to the cation efflux proteins, the Escherichia coli potassium ion-translocating protein, KefC, and the putative Na+/H(+)-antiporter, NapA, from Enterococcus hirae. Northern hybridization demonstrated that the magA mRNA transcript is 1.3 kilobases in size, corresponding to the size of the magA gene. A functional promoter was located upstream from the magA gene, and the transcription in AMB-1 was regulated by environmental iron concentration. Vesicles isolated from E. coli in which the MagA protein was expressed exhibited iron accumulation ability. We consider that the MagA protein is an iron transport involved in the synthesis of magnetic particles in AMB-1.