gebhart/patrepeval huggingface dataset:
Reproductive impact of congenital Mullerian anomalies (1997)

This retrospective longitudinal study was undertaken in order to determine the incidence and reproductive impact of uterine malformations on women desiring to conceive during their reproductive years. A total of 3181 patients in whom the morphology of the uterus was ascertained by hysterosalpingography (HSG) and laparoscopy/laparotomy during the years 1980-1995 was included in the study. The population analysed included fertile, infertile and sterile patients. The overall frequency of uterine malformations was 4.0%. Infertile patients (6.3%) had a significantly (P < 0.05) higher incidence of Müllerian anomalies, in comparison with fertile (3.8%) and sterile (2.4%) women. Septate (33.6%) and arcuate (32.8%) uteri were the most common malformations observed. Each malformation was individually analysed in fertile and infertile patients, in order to ascertain its actual reproductive impact. The performance of the unicornuate and didelphys uteri was similar with a chance of having a living child of 37-40%. The reproductive potential of the bicornuate uterus showed a live birth rate of 62.5% and the septate uterus showed a live birth rate of 62%. In all these abnormalities, early miscarriages (25-38%) and preterm deliveries (25-47%) were quite common. The arcuate uterus presented a live birth rate of 82.7%. It is concluded that uterine anomalies are relatively frequent in fertile women, and more frequent in infertile patients. Nevertheless, fertile patients with normal reproductive performance do exist, and Müllerian defects can permit an absolutely normal obstetric outcome. The reproductive performance of the unicornuate and didelphys uteri was poor, while that of the septate and bicornuate uteri was better than expected. The arcuate uterus had no impact on reproduction.
Infrared hot-electron transistor with a narrow bandpass filter for high temperature operation (1995)

We have designed and demonstrated a narrow bandpass filter, which is composed of a double-barrier structure, for an infrared hot-electron transistor with a cutoff wavelength at 14 μm. The filter is capable of suppressing the low energy thermally assisted tunneling current as well as the high energy thermionic emission current that are not degenerate with the photoelectrons. As a result, the detector can be operated at 77 K with a 45% BLIP level and an estimated NEΔT of 38 mK.
Cramer-Rao bounds for long-wave infrared gaseous plume quantification (2013)

The central parameter in the quantification of chemical vapor plumes via remote sensing is the mean concentration-path length (CL) product, which can be combined with scene geometry information to provide estimates of the absolute gas quantity present. We derive Cramer-Rao lower bounds on the variance of an unbiased estimator of CL in concert with other parameters of a nonlinear radiance model. These bounds offer a guide to feasibility of CL estimation that is not dependent on any given algorithm. In addition, the derivation of the bounds yields great insight into the physical and phenomenological mechanisms that control plume quantification, which we illustrate with examples representing a variety of experimental scenarios.
Confined-solution process for high-quality CH3NH3PbBr3 single crystals with controllable morphologies (2017)

Solution processes have shown excellent potential for application to the growth of single-crystal materials. We have developed a confined-solution method for the preparation of single crystals with a controlled morphology. By confining the precursor solution within a micrometer-thick cavity and then controlling the saturation by adjusting the temperature gradient and fluid flow, high-quality CH3NH3PbBr3 single crystals with tunable morphologies could be obtained. The morphologies of the CH3NH3PbBr3 can be adjusted from sub-square centimeter-scale thin sheets that are square or rectangular, to one-dimensional wires with lengths in the order of centimeters, simply by changing the temperature. The thicknesses of the CH3NH3PbBr3 sheets could be adjusted from hundreds of nanometers to tens of microns. The CH3NH3PbBr3 sheets feature very clean surfaces with an atomic-scale roughness. This simple strategy provides a means of growing high-quality single crystals with clean surfaces, which realize high levels of performance when applied to devices.
Development of DNA Chip Microarrayer (2000)

A microarrayer system was developed mainly for manufacturing DNA chips. The 3-axis robot was designed to automatically collect samples from 96- or 384-well microtiter plates using up to 16 simultaneously moving pens and to deposit them on a surface-modified slide glass. This is followed by a wash/dry operation in a clean station. The cycle is repeated with a new set of samples. This system can deposit cDNA or oligonucleotides with spot intervals of 150 μm and the spot size of 80 μm, thus allowing a high density DNA chip containing about 5,000 spots per cm 2 . The entire procedure is controlled by the Visual C++ program that was written in our laboratory by using a personal computer with Pentium 100 CPU.
Reconstruction of Signaling Networks Regulating Fungal Morphogenesis by Transcriptomics (2009)

Coordinated control of hyphal elongation and branching is essential for sustaining mycelial growth of filamentous fungi. In order to study the molecular machinery ensuring polarity control in the industrial fungus Aspergillus niger, we took advantage of the temperature-sensitive (ts) apical-branching ramosa-1 mutant. We show here that this strain serves as an excellent model system to study critical steps of polar growth control during mycelial development and report for the first time a transcriptomic fingerprint of apical branching for a filamentous fungus. This fingerprint indicates that several signal transduction pathways, including TORC2, phospholipid, calcium, and cell wall integrity signaling, concertedly act to control apical branching. We furthermore identified the genetic locus affected in the ramosa-1 mutant by complementation of the ts phenotype. Sequence analyses demonstrated that a single amino acid exchange in the RmsA protein is responsible for induced apical branching of the ramosa-1 mutant. Deletion experiments showed that the corresponding rmsA gene is essential for the growth of A. niger, and complementation analyses with Saccharomyces cerevisiae evidenced that RmsA serves as a functional equivalent of the TORC2 component Avo1p. TORC2 signaling is required for actin polarization and cell wall integrity in S. cerevisiae. Congruently, our microscopic investigations showed that polarized actin organization and chitin deposition are disturbed in the ramosa-1 mutant. The integration of the transcriptomic, genetic, and phenotypic data obtained in this study allowed us to reconstruct a model for cellular events involved in apical branching.
A High-Performance Cycloconverter-Fed Synchronous Machine Drive System (1984)

A high-performance variable-speed drive system using a cycloconverter-fed synchronous machine is described. The principle of the drive control is based on the field-oriented control method. For operating the synchronous machine drive system with high dynamic performance and excellent static characteristics over a wide range from zero to top speed, accurate field orientation and high response current control are particularly important problems to be solved. New methods of solving these problems are presented. This systems was manufactured for a 2500-kW reversible rolling mill drive system, using a six-pulse three- phase cycloconverter and an ordinary rotating field type synchronous machine without any special requirements. The expected performance was successfully obtained.
Formation of 1-deoxy-ketoses by pyruvate dehydrogenase and acetoin dehydrogenase. (1986)

Cell-free extracts of Bacillus subtilis contain enzyme activities which catalyze an acyloin-type condensation reaction (carboligase reaction) resulting in the formation of l-deoxy-ketoses. The reactions are deduced to proceed as follows: pyruvate+aldose→CO2+1-deoxy-ketose (I) acetoin+aldose→acetaldehyde+1-deoxy-ketose (II) methylacetoin + aldose→acetone+1-deoxy-ketose (III) Experiments with mutants of B. subtilis defective in pyruvate dehydrogenase (PDH) or acetoin dehydrogenase (AccDH) and with partially purified enzyme preparations revealed that PDH (EC 1.2.4.1) catalyzes reaction (I), and AccDH catalyzes reactions (II) and (III). That the PDH purified from Escherichia coli and the PDC purified from bovine heart also catalyzed reaction (I) indicates that 1 -deoxy-ketose-forming activities are widely distributed. One of the reactions catalyzed by these enzymes is the formation of 1-deoxy-D-threo-pentulose, a precursor of biosynthesis of thiazole ring of thiamine.
Sequential Window Diagnoser for Discrete-Event Systems Under Unreliable Observations (2009)

This paper addresses the issue of counting the occurrence of special events in the framework of partiallyobserved discrete-event dynamical systems (DEDS). Developed diagnosers referred to as sequential window diagnosers (SWDs) utilize the stochastic diagnoser probability transition matrices developed in [9] along with a resetting mechanism that allows on-line monitoring of special event occurrences. To illustrate their performance, the SWDs are applied to detect and count the occurrence of special events in a particular DEDS. Results show that SWDs are able to accurately track the number of times special events occur.
Towards Understanding Cloud Performance Tradeoffs Using Statistical Workload Analysis and Replay (2010)

Cloud computing has given rise to a variety of distributed applications that rely on the ability to harness commodity resources for large scale computations. The inherent performance variability in these applications' workload coupled with the system's heterogeneity render ineffective heuristics-based design decisions such as system configuration, application partitioning and placement, and job scheduling. Furthermore, the cloud operator's objective to maximize utilization conflicts with cloud application developers' goals of minimizing latency, necessitating systematic approaches to tradeoff these optimization angles. One important cloud application that highlights these tradeoffs is MapReduce. In this paper, we demonstrate a systematic approach to reasoning about cloud performance tradeoffs using a tool we developed called Statistical Workload Analysis and Replay for MapReduce (SWARM). We use SWARM to generate realistic workloads to examine latency-utilization tradeoffs in MapReduce. SWARM enables us to infer that batched and multi-tenant execution effectively balance the tradeoff between latency and cluster utilization, a key insight for cloud operators.
The isolation of an allergen from extracts of Dermatophagoides pteronyssinus using a murine IgA myeloma with a specificity for phosphorylcholine (1980)

The presence of a high molecular weight glycoprotein component bearing the hapten phosphorylcholine (Pc) has been demonstrated in some but not all extracts of house dust mite using a phosphorylcholine specific IgA myeloma protein (S107). The Pc bearing component was isolated from house dust mite extracts by precipitation at equivalence using whole myeloma serum and the isolated fraction was found to be allergenic as judged by a direct RAST assay using a highly house dust mite allergic human serum pool. RAST inhibition studies using free hapten and direct RAST studies using pneumococcal polysaccharide C-substance indicated that the Pe moiety did not contribute significantly to the immunodominant portion of the isolated allergen. Further studies indicated that the S107 isolated material was immunochemically different from the tridacnin reactive material and the con A reactive material previously isolated fom extracts of house dust mite.
Coaxial thin film transducers based on PZT (2003)

The results of the piezoelectric and acoustic experiments on thin films of lead zirconate titanate (PZT) coated coaxially on optical fibers with a gold or an aluminum thin jacket are presented. The PZT films are fabricated by sol-gel processing using dip coating. Coating lengths of 10-cm and film thicknesses up to 6 mu m have been achieved. The piezoelectricity is induced by electric poling. Potential applications in medical and inline fiber optical acousto-optic devices are discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
A fully integrated &#x00B1;5A current-sensing system with &#x00B1;0.25% gain error and 12&#x03BC;&#x0391; offset from &#x2212;40&#x00B0;C to &#x002B;85&#x00B0;C (2015)

This paper presents a fully integrated current-sensing system (CSS) that is 10x more accurate than the state-of-the-art. It consists of an on-chip shunt resistor, a ΔΣ ADC and a bandgap reference (BGR), which also senses shunt temperature. For ±5A currents, it exhibits 12μA offset and ±0.25% gain error from -40 to +85°C. This level of accuracy is achieved with the help of multiple dynamic error correction techniques, a shunt temperature compensation scheme and chip-scale packaging for low thermal and electrical resistance.
High Density Formation and Magnetoelectronic Transport Properties of Fe3Si Nanodots (2018)

We fabricated DO3-orderd Fe3Si-nanodots (NDs) on ultrathin SiO2 and evaluated local I-V characteristics through individual dots under magnetic field application by using atomic force microscopy (AFM) with a magnetic cantilever. High-density Fe-silicide NDs with an areal density as high as ~1011 cm-2 were formed on thermally grown SiO2 by exposing ultrathin Fe/amorphous-Si/Fe tri-layer stacked structures to a remote H2 plasma without external heating. The formation of DO3-orderd NDs was confirmed by X-ray diffraction and magnetization measurements. From local electron transport properties, a clear change in resistance depending on the magnetization direction of Fe3Si-NDs with respect to the CoPtCr-coated AFM tip was confirmed at room temperature.
A RETROSPECTIVE STUDY ON ANTIBIOTIC USAGE IN A TERTIARY CARE HOSPITAL (2020)

Antibiotics are one of the most commonly prescribed drugs today. Rational use of antibiotics is therefore extremely important as their injudicious use can adversely affect the patient. Drug Utilization Evaluation (DUE) is a system of ongoing systematic criteria based evaluation of drug that will help to ensure that medicines are used appropriately. It is drug/disease specific and can be structured so that it will assess the actual process of prescribing, dispensing, or administration of drug. The retrospective study was conducted At Pk Das Institute of Medical Sciences, Palakkad, Kerala for a duration of 6 months (February 2017 - January 2018). A source of data includes Patient case sheets &amp;medication charts, nursing charts, culture &amp; sensitivity reports. The inclusion criterion includes Patients aged between 18- 80 year, prescribed with oral and parenteral antibiotics. . On analyzing the gender, male gender (n= 111, 55.5%) were higher in numbers as compared to female counterparts (n=89, 44.5%). In our study the majority of the patients prescribed with antibiotics were with the clinical assessment of COPD (n=39, 19.5%), UTI (n=37, 18.5%) and LRTI (n=28, 14%), Bronchial asthma (n=19, 9.5%) respectively. On analyzing the data based on antibiotic sensitivity test, antibiotic test were performed and followed in (n=64,32%)prescriptions and in (n=47,23.5%)prescriptions were test is not followed respectively. In (n=89,44.5%) prescriptions, antibiotic sensitivity test is not performed. On analysis of antibiotics prescribed, the most commonly prescribed antibiotics were cephalosporins, of these ceftriaxone was highly prescribed of all (n=95). The high percentage of antibiotic prescriptions may indicate a high probability of irrational use. This study also point out irrational use of antibiotics are more leading to resistance, misuse and serious problems. So certain strategies should be put forward to strengthen rational use of antibiotics.&#x0D; Keywords: Antibiotics, Antibiotic Susceptibility Test, Irrational use, Resistance
Spatially resolved measurements of hyperpolarized gas properties in the lung in vivo. Part I: Diffusion coefficient (1999)

In imaging of hyperpolarized noble gases, a knowledge of the diffusion coefficient (D) is important both as a contrast mechanism and in the design of pulse sequences. We have made diffusion coefficient maps of both hyperpolarized (3)He and (129)Xe in guinea pig lungs. Along the length of the trachea, (3)He D values were on average 2.4 cm(2)/sec, closely reproducing calculated values for free gas (2.05 cm(2)/sec). The (3)He D values measured perpendicular to the length of the trachea were approximately a factor of two less, indicating restriction to diffusion. Further evidence of restricted diffusion was seen in the distal pulmonary airspaces as the average (3)He D was 0.16 cm(2)/sec. An additional cause for the smaller (3)He D in the lung was due to the presence of air, which is composed of heavier and larger gases. The (129)Xe results show similar trends, with the trachea D averaging 0.068 cm(2)/sec and the lung D averaging 0.021 cm(2)/sec. Magn Reson Med 42:721-728, 1999.
Technology developments for the next generation of spaceborne SAR instruments based on digital beamforming (2012)

During the past ten years a number of research groups around the world have been investigating the use of digital beamforming for spaceborne SAR instruments. The separate optimization of the effective transmit and receive aperture sizes together with the splitting of the receive side into multiple receive sub-apertures which can be combined on board by means of digital beamforming allows for a number of new SAR modes. With this it is for example possible to overcome the principle swath width and azimuth resolution limitation known in classical SAR instrument designs. ESA has performed and initiated a number of systems studies to identify the critical technologies needed for this type of instrument. Based on these system studies a number of technology development activities have been started. This paper gives an overview on the studies and technology developments performed in this context.
TGF-β Signaling Regulates Pancreatic β-Cell Proliferation through Control of Cell Cycle Regulator p27 Expression (2013)

Proliferation of pancreatic β-cells is an important mechanism underlying β-cell mass adaptation to metabolic demands. Increasing β-cell mass by regeneration may ameliorate or correct both type 1 and type 2 diabetes, which both result from inadequate production of insulin by β-cells of the pancreatic islet. Transforming growth factor β (TGF-β) signaling is essential for fetal development and growth of pancreatic islets. In this study, we exposed HIT-T15, a clonal pancreatic β-cell line, to TGF-β signaling. We found that inhibition of TGF-β signaling promotes proliferation of the cells significantly, while TGF-β signaling stimulation inhibits proliferation of the cells remarkably. We confirmed that this proliferative regulation by TGF-β signaling is due to the changed expression of the cell cycle regulator p27. Furthermore, we demonstrated that there is no observed effect on transcriptional activity of p27 by TGF-β signaling. Our data show that TGF-β signaling mediates the cell-cycle progression of pancreatic β-cells by regulating the nuclear localization of CDK inhibitor, p27. Inhibition of TGF-β signaling reduces the nuclear accumulation of p27, and as a result this inhibition promotes proliferation of β-cells.
INFLUENCE OF Urochloa brizantha ON THE GROWTH AND NUTRITIONAL ABSORPTION OF TREE SPECIES (2020)

Influence of Urochloa brizantha on the growth and nutritional absorption of tree species. The objective of this study was to evaluate the influence of Urochloa brizantha var. Marandu on the growth and accumulation of macronutrients in the leaves of Cordia trichotoma and Guarea guidonia. Seedlings of tree species were transplanted to 18-liter pots and kept free of U. brizantha for three months. After that period, three treatments were adopted that consisted of the control (T0), two plants of U. brizantha per pot (T2) and four plants of U. brizantha per pot (T4). Growth and nutrient accumulation of tree species were evaluated after 84 days of coexistence with U. brizantha. The increment in diameter, of both tree species, leaf area and shoot dry matter of G. guidonia were significantly affected by the presence of U. brizantha, compared to the control. Significant differences were observed for the accumulation of potassium and magnesium in the leaves of C. trichotoma.
Collagen‐Based Systems to Mimic the Extracellular Environment (2022)

Collagen is the most abundant protein found in the human body. There are 29 different types of collagen that can be found in human tissues with predominance in the musculoskeletal system. Collagen is represented in either cell-rich or matrix-rich structures where it plays an important role both structurally and in directing cellular and tissue function. As current research focuses on culturing cells within their native microenvironment, or niche, much work is now devoted to the use of biophysical cues that direct cell growth and behavior and includes native extracellular matrix proteins. Among these, collagen is an ideal target candidate as a biomimetic 3D matrix to culture cells in and to recapitulate the native biophysical microenvironment of tissues in situ . Different strategies to control collagen architecture and function are overviewed in this chapter, as well as the pertinent rationale behind the use of collagen as a biomaterial scaffold.
ChemInform Abstract: 7‐Deazaguanosine: Synthesis of an Oligoribonucleotide Building Block and Disaggregation of the U‐G‐G‐G‐G‐U G4 Structure by the Modified Base. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Devil in the Details: Towards Accurate Single and Multiple Human Parsing (2018)

Human parsing has received considerable interest due to its wide application potentials. Nevertheless, it is still unclear how to develop an accurate human parsing system in an efficient and elegant way. In this paper, we identify several useful properties, including feature resolution, global context information and edge details, and perform rigorous analyses to reveal how to leverage them to benefit the human parsing task. The advantages of these useful properties finally result in a simple yet effective Context Embedding with Edge Perceiving (CE2P) framework for single human parsing. Our CE2P is end-to-end trainable and can be easily adopted for conducting multiple human parsing. Benefiting the superiority of CE2P, we achieved the 1st places on all three human parsing benchmarks. Without any bells and whistles, we achieved 56.50\% (mIoU), 45.31\% (mean $AP^r$) and 33.34\% ($AP^p_{0.5}$) in LIP, CIHP and MHP v2.0, which outperform the state-of-the-arts more than 2.06\%, 3.81\% and 1.87\%, respectively. We hope our CE2P will serve as a solid baseline and help ease future research in single/multiple human parsing. Code has been made available at \url{https://github.com/liutinglt/CE2P}.