gebhart/patrepeval huggingface dataset:
Experimental real-time voltage and frequency controllers for a synchronous generator implemented in a laboratory power system test-bed (2008)

A new experiment for undergraduates showing voltage and frequency control of a small alternator for a two bus power system is introduced. Voltage and frequency controllers were designed in Simulink and implemented using dSPACE. A subsystem of the scaled down power system testbed developed at Florida International University was utilized to study the effects of varying load on the generator operating voltage and frequency. Hardware-in-the-Loop, power converter and fuzzy logic controllers were included in the experiment to underscore the importance of control systems, power electronics and application of artificial intelligence in power systems.
Effects of wafer bow and warpage on the integrity of thin gate oxides (1994)

We have studied the effects of initial wafer bow and warpage on the integrity of thinner gate oxides grown by both furnace and rapid thermal processing (RTP) methods. There is evidence of a correlation between wafer warpage and bow to the charge-to-breakdown characteristics of the gate oxide. An almost linear increase in defect density was observed when plotted as a function of increasing wafer warpage. The lifetime (t50%) of the samples with initial warpage of 10 μm or less is reported higher than those with initial warpage of more than 60 μm for both furnace and RTP-grown oxides. The value of bow for the warped samples was taken for cases with the highest positive and negative values so both kinds of shape trends could be investigated. With initial wafer warpage ranging from 4 to 70 μm, we present the results of wafer dimensional analysis and correlate these to defect density and lifetime studies for thin gate oxides.
Stabilization of granulocyte-macrophage colony-stimulating factor RNA in a human eosinophil-like cell line requires the AUUUA motifs. (1999)

Human eosinophils activated by calcium ionophore produce granulocyte-macrophage colony-stimulating factor (GM-CSF). In T lymphocytes GM-CSF messenger RNA (mRNA) stability is regulated by 3' untranslated region (UTR) adenosine-uridine-rich elements (AREs). We show endogenous GM-CSF mRNA is rapidly induced in an eosinophil cell-line (AML14.3D10) after activation with ionomycin. To calculate the decay rate of GM-CSF mRNA in activated cells, eosinophils were transfected with wild-type, full-length GM-CSF mRNA or a mutant version lacking the AUUUA motifs. In unstimulated cells, wild-type GM-CSF mRNA decayed with a half-life time (t1/2) of 6+/-2 min while the mutant decayed with a t1/2 of 20+/-4 min, demonstrating the dominant, destabilizing effect of multiple AUUUA motifs. Within 1 hr of activation by ionomycin, the half-life of transfected wild-type mRNA increased by 2.5-fold, which increased up to 4-fold after 2 hr of activation. The half-life of the mutant GM-CSF was unaffected by ionomycin, demonstrating that ionophore-mediated stabilization requires intact AUUUA motifs. Actinomycin D (ActD) stabilized wild-type GM-CSF mRNA as well, causing poly(A) tail elongation and translation inhibition. These data show that in eosinophil-like cell lines, GM-CSF mRNA is exquisitely unstable but can be markedly stabilized by calcium ionophore. Both effects require intact 3' UTR AREs.
Prosthetic Left Ventricle for Continuous Pressure Assistance (1965)

Two BASIC approaches to the development of an "artificial heart" have been introduced by several groups of investigators: total replacement of the diseased heart by pumps contained within the vacated pericardial space<sup>1-8</sup>and intrathoracic bypass pumps which divert the flow of blood past the diseased ventricle or ventricles, thus reducing the flow work<sup>9,10</sup>(Fig 1). The inlet of such a pump is anastomosed to the left atrium and the outlet is anastomosed to the aorta. Inlet (mitral) and outlet (aortic) prosthetic valves must be provided to assume the function of mitral and aortic valves respectively. A third basic approach is presented in this study (Fig 2). The prosthetic ventricle serves to reduce the pressure against which the disease ventricle must eject its stroke volume to the extent that the diseased ventricle is performing the function of an auxiliary left atrium. The pressure work of the physiologic ventricle is
The Solubility of C60Fullerene in Long Chain Fatty Acids Esters (2007)

Abstract A series of fatty acid esters of glycerol as linseed, sunflower, soybean and olive oils have been tested as C60 fullerene solvents together with a mixture of methyl ester fatty acids derived from brassica oilseeds and used as a biofuel known as “biodiesel.” All the oils evaluated are effective solvents of C60. The solubility of C60 in the selected vegetable oils has been determined spectrophotometrically. The C60 solubility in vegetable oils may pave the way for easier application of C60 fullerene in medicinal chemistry and in additive chemistry for varnishes and fuels. It has been found that C60 is not only soluble in the fatty acid esters but is also reactive with them under mild conditions, giving addition products easily recognized by a characteristic absorption band at 435 nm. The addition reaction mechanism has been discussed.
Solubilization and Reconstitution of a Lysosomal H+-Pump1 (1984)

H+-ATPase was solubilized from the lysosomal membranes of rat liver with lysophosphatidylcholine. The detergent was removed with Biobeads SM2, and the proteoliposomes were prepared by rapid dilution of a mixture of the solubilized ATPase, octyl-beta-D-glucopyranoside and liposomes. The proteoliposomes exhibited ATP-dependent fluorescence quenching of quinacrine and bis(3-phenyl-5-oxoisoxasol-4-yl)pentamethine oxonol. These results suggested that the electrogenic lysosomal H+-pump was solubilized and reconstituted into proteoliposomes.
Optical design forms for DUV and VUV microlithographic processes (2001)

Microlithographic objectives have been developed for deep ultraviolet and vacuum ultraviolet wavelengths used for printing and inspection applications related to microlithographic processes. Refractive and catadioptric design solutions using fused silica, calcium fluoride and other crystals are discussed. Several reflective and catadioptric design forms having central obscurations will be compared to refractive forms. Design complexity, performance and limitations are compared.
Formation of Bisnitrosocyclohexane and Cyclohexanone Oxime by Silent Electric Discharge (1971)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFormation of Bisnitrosocyclohexane and Cyclohexanone Oxime by Silent Electric DischargeJohn H. WagenknechtCite this: Ind. Eng. Chem. Prod. Res. Dev. 1971, 10, 2, 184–189Publication Date (Print):June 1, 1971Publication History Published online1 May 2002Published inissue 1 June 1971https://pubs.acs.org/doi/10.1021/i360038a015https://doi.org/10.1021/i360038a015research-articleACS PublicationsRequest reuse permissionsArticle Views37Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Influence of LiCl on the Morphology,Structure and Properties of Aliphatic Polyurethaneurea (2006)

The effect of LiCl on the viscosity of polyurethaneurea(PUU) solution,and structures and properties of PUU films was studied by using FT-IR and DSC.The results show that the viscosity of PUU solution decrease first by adding LiCl,but then increase.Because of the coordination of LiCl with ether and carbonyl groups existed in the PUU films,the value of T_g and the degree of ordered hydrogen bonding of urethane groups in the PUU films increased by adding LiCl into PUU films,but the degree of ordered hydrogen bonding of urea groups in the PUU films decreased.The tensile modulus,hardness and tear strength of the PUU films can be enhanced appreciably by adding LiCl into the PUU films.However,the water absorption of the PUU films containing LiCl was higher than that of the PUU film without LiCl.
Coexpression Studies with Endothelin Receptor Subtypes Indicate the Existence of Intracellular Cross-Talk between ETA and ETB Receptors (1997)

Human Girardi heart cells expressing endothelin ET(B) receptors (GH(B) cells) were transfected with human ET(A) cDNA, and coexpression of ET(A) and ET(B) in the ratio of 4:6 was demonstrated by Scatchard analysis. [125I]Endothelin (ET)-1 binding to ET(A)-transfected GH cells (GH(AB) cells) was displaced by an ET(A) antagonist, BQ-123, in a biphasic manner. An ET(B) agonist, BQ-3020, and an ET(B) antagonist, BQ-788, inhibited [125I]ET-1 binding to GH(AB) cells in a monophasic manner with low affinities (IC50 = 2,800 and 890 nM, respectively); IC50 values for ET(B) receptors seemed to be as weak as those for ET(A) receptors. However, BQ-3020 and BQ-788 had a high affinity for ET(B) receptors in a binding experiment using [125I]ET-1 in the presence of 1 microM BQ-123, where ET(A) receptors are masked (IC50 = 0.49 and 0.89 nM, respectively). The ET(B)-mediated increase in intracellular calcium concentrations in GH(AB) cells was not affected by 0.1 microM BQ-788 alone but was inhibited significantly by the same concentration of BQ-788 in combination with 10 microM BQ-123. ET-1 suppressed forskolin-stimulated accumulation of cAMP through the activation of ET(A) and ET(B) in GH(AB) cells; 1 microM BQ-123 or BQ-788 inhibited the suppression by only 20%, whereas a mixture of BQ-123 and BQ-788 (1 microM each) completely inhibited the cAMP decrease. These findings suggest that the stimulation of ET(A) receptors with ET-1 results in a lowering of the affinity of BQ-3020 and BQ-788 for ET(B) receptors in GH(AB) cells. We conclude that there is intracellular cross-talk between ET(A) and ET(B) receptors in GH(AB) cells.
Simulation of a drop-on-demand print head with planar piezoelectric transducer (2003)

The improvement of the design of a drop-on-demand ink-jet printhead by means of a simulation program is investigated. The constructional concept behind this printhead is an adaptation of existing designs using piezoelectric bilaminar transducers. The ruling physical effects are discussed to get a suitable model with appropriate simplifications. On the basis of the finite-element method, the dynamic behavior of the drop-generator is derived. Comparison with experimental data yields small deviations.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Pulmonary Hypertension Complicating Connective Tissue Disease (2013)

Pulmonary hypertension (PH) may complicate connective tissue disease (CTD), particularly systemic sclerosis (SSc, scleroderma), and markedly increases mortality. More than 70% of cases of PH complicating CTD occur in SSc, which is the major focus of this article. Pulmonary complications (i.e., interstitial lung disease [ILD] and PH) are the leading causes of scleroderma-related deaths. "Isolated" PH (i.e., without ILD) complicates SSc in 7.5 to 20% of cases; secondary PH may also occur in patients with SSc-associated ILD. Several clinical markers and specific autoantibody profiles have been associated with PH in SSc. The role of PH-specific therapy is controversial, as prognosis and responsiveness to therapy are worse in SSc-associated PH compared with idiopathic pulmonary arterial hypertension. We discuss medical therapies for CTD-associated PH and the role of lung transplantation for patients failing medical therapy.
Stability of binding of label from N-hydroxy-N-2-fluorenylacetamide to intracellular targets, particularly deoxyribonucleic acid in rat liver. (1969)

The stability of the binding of radioactive metabolites from the carcinogen N -hydroxy- N -2-fluorenylacetamide to macromolecular elements in rat liver was studied after a single dose of compound and after 2 and 10 weeks of dietary intake of the labeled carcinogen. After a single dose the label of carcinogen bound to DNA decreased in two discrete steps. After the initial peak at 24 hours, the bound label decreased with a half-life of 10 hours, then declined with a half-life of about 33 hours between the 4th and 12th day by when virtually all the label was lost. In cytoplasmic fractions the label decreased to zero in 24 days. The persistence of label introduced into DNA with tritiated thymidine was found to be relatively uniform between Day 6 and Day 72 after a single dose.

The initial peak value of carcinogen bound to DNA, the microsomal fraction, and the soluble fraction, was higher after continuous intake of 2 weeks than after 10 weeks. On the DNA the maximum binding corresponded to about 11,000 nucleotide units for 1 molecule of carcinogen. The rate of decrease was similar for the 2-week and the 10-week groups for the first few days after cessation of labeled carcinogen intake. Subsequently the decline of bound activity was slower in the 10-week group than in the 2-week group. With this type of carcinogen, measurement of the interaction between agent and cellular elements performed after feeding of the compound for a time period eventuating in cancer is more relevant to an understanding of the process than is the measurement performed after single dosing.
ChemInform Abstract: Bz1 Receptor Subtype Specific Ligands. Synthesis and Biological Properties of βCCt, a Bz1 Receptor Subtype Specific Antagonist. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Self‐Assembling Nanoparticles at Surfaces and Interfaces (2007)

Nanoparticles are the focus of much attention due to their astonishing properties and numerous possibilities for applications in nanotechnology. For realising versatile functions, assembly of nanoparticles in regular patterns on surfaces and at interfaces is required. Assembling nanoparticles generates new nanostructures, which have unforeseen collective, intrinsic physical properties. These properties can be exploited for multipurpose applications in nanoelectronics, spintronics, sensors, etc. This review surveys different techniques, currently employed and being developed, for assembling nanoparticles in to ordered nanostructures. In this endeavour, the principles and methods involved in the development of assemblies are discussed. Subsequently, different possibilities of nanoparticle-based nanostructures, obtained in multi-dimensions, are presented.
Mutational analysis using oligonucleotide microarrays (1999)

The development of inexpensive high throughput methods to identify individual DNA sequence differences is important to the future growth of medical genetics. This has become increasingly apparent as epidemiologists, pathologists, and clinical geneticists focus more attention on the molecular basis of complex multifactorial diseases. Such undertakings will rely upon genetic maps based upon newly discovered, common, single nucleotide polymorphisms. Furthermore, candidate gene approaches used in identifying disease associated genes necessitate screening large sequence blocks for changes tracking with the disease state. Even after such genes are isolated, large scale mutational analyses will often be needed for risk assessment studies to define the likely medical consequences of carrying a mutated gene. This review concentrates on the use of oligonucleotide arrays for hybridisation based comparative sequence analysis. Technological advances within the past decade have made it possible to apply this technology to many different aspects of medical genetics. These applications range from the detection and scoring of single nucleotide polymorphisms to mutational analysis of large genes. Although we discuss published scientific reports, unpublished work from the private sector could also significantly affect the future of this technology.
Diagnosis of Hashimoto’s thyroiditis in ultrasound using tissue characterization and pixel classification (2013)

Hashimoto’s thyroiditis is the most common type of inflammation of the thyroid gland, and accurate diagnosis of Hashimoto’s thyroiditis would be helpful to better manage the disease process and predict thyroid failure. Most of the published computer-based techniques that use ultrasound thyroid images for Hashimoto’s thyroiditis diagnosis are limited by lack of procedure standardization because individual investigators use various initial ultrasound settings. This article presents a computer-aided diagnostic technique that uses grayscale features and classifiers to provide a more objective and reproducible classification of normal and Hashimoto’s thyroiditis-affected cases. In this paradigm, we extracted grayscale features based on entropy, Gabor wavelet, moments, image texture, and higher order spectra from the 100 normal and 100 Hashimoto’s thyroiditis-affected ultrasound thyroid images. Significant features were selected using t-test. The resulting feature vectors were used to build the following three classifiers using tenfold stratified cross validation technique: support vector machine, k-nearest neighbor, and radial basis probabilistic neural network. Our results show that a combination of 12 features coupled with support vector machine classifier with the polynomial kernel of order 1 and linear kernel gives the highest accuracy of 80%, sensitivity of 76%, specificity of 84%, and positive predictive value of 83.3% for the detection of Hashimoto’s thyroiditis. The proposed computer-aided diagnostic system uses novel features that have not yet been explored for Hashimoto’s thyroiditis diagnosis. Even though the accuracy is only 80%, the presented preliminary results are encouraging to warrant analysis of more such powerful features on larger databases.
Characterization of the N-terminal Domain of the Yeast Transcriptional Repressor Tup1 (2000)

The yeast Tup1 and Ssn6 proteins form a transcriptional repression complex that represses transcription of a broad array of genes. It has been shown that the N-terminal domain of the Tup1 protein interacts with a region of the Ssn6 protein that consists of 10 tandem copies of a tetratricopeptide motif. In this work, we use a surface plasmon resonance assay to measure the affinity of the N-terminal domain of Tup1 for a minimal 3-TPR domain of Saccharomyces cerevisiae Ssn6 that is sufficient for binding to Tup1. This domain of Ssn6 binds with comparable affinity to S. cerevisiae and Candida albicans Tup1, but with 100-fold lower affinity to Tup1 protein containing a point mutation that gives rise to a defect in repression in vivo. Results from studies using analytical ultracentrifugation, CD spectroscopy, limited proteolysis, and (1)H NMR show that this domain of Tup1 is primarily alpha-helical and forms a stable tetramer that is highly nonglobular in shape. X-ray diffraction recorded from poorly ordered crystals of the Tup1 tetramerization domain contains fiber diffraction typical of a coiled coil. Our results are used to propose a model for the structure of the N-terminal domain of Tup1 and its interaction with the Ssn6 protein.
The p recombination layer in tunnel junctions for micromorph tandem solar cells (2011)

A new tunnel recombination junction is fabricated for n—i—p type micromorph tandem solar cells. We insert a thin heavily doped hydrogenated amorphous silicon (a-Si:H) p+ recombination layer between the n a-Si:H and the p hydrogenated nanocrystalline silicon (nc-Si:H) layers to improve the performance of the n—i—p tandem solar cells. The effects of the boron doping gas ratio and the deposition time of the p-a-Si:H recombination layer on the tunnel recombination junctions have been investigated. The current-voltage characteristic of the tunnel recombination junction shows a nearly ohmic characteristic, and the resistance of the tunnel recombination junction can be as low as 1.5 Ω·cm2 by using the optimized p-a-Si:H recombination layer. We obtain tandem solar cells with open circuit voltage Voc = 1.4 V, which is nearly the sum of the Vocs of the two corresponding single cells, indicating no Voc losses at the tunnel recombination junction.
Adaptive calibration of a three-microphone system for acoustic waveguide characterization under time-varying conditions (2014)

The pressure and velocity field in a one-dimensional acoustic waveguide can be sensed in a non-intrusive manner using spatially distributed microphones. Experimental characterization with sensor arrangements of this type has many applications in measurement and control. This paper presents a method for measuring the acoustic variables in a duct under fluctuating propagation conditions with specific focus on in-system calibration and tracking of the system parameters of a three-microphone measurement configuration. The tractability of the non-linear optimization problem that results from taking a parametric approach is investigated alongside the influence of extraneous measurement noise on the parameter estimates. The validity and accuracy of the method are experimentally assessed in terms of the ability of the calibrated system to separate the propagating waves under controlled conditions. The tracking performance is tested through measurements with a time-varying mean flow, including an experiment conducted under propagation conditions similar to those in a wind instrument during playing.