gebhart/patrepeval huggingface dataset:
The diffusion coefficient controlling crystal growth in a silicate glass‐former (2017)

Abstract One of the most relevant open issues in glass science refers to our ignorance concerning the nature of the diffusing entities that control crystal nucleation and growth in non‐crystalline materials. This information is very relevant because all the existing nucleation and growth equations account for the diffusion coefficient ( D U ) of these unknown entities. In this article, we measured the shear viscosity (η) and the crystal growth rates of a supercooled diopside liquid (CaMgSi 2 O 6 ) in a wide temperature range. The well‐known decoupling of viscosity and crystal growth rates at deep supercoolings was detected. We tested and analyzed 4 different approaches to compute D U , three existing and one proposed here. As expected, the classical approach ( D U ~ η −1 ) and the fractional viscosity approach ( D U ~ η −ε ) were not able to describe the crystal growth rates near the glass transition temperature. However, our proposed expression to calculate D U —gradually changing from a viscosity‐controlled to an Arrhenian‐controlled process—was able to describe the available data in the whole temperature range and yielded the lowest uncertainty for the adjustable parameters. Our results suggest that viscous flow ceases to control the crystal growth process below the so‐called decoupling temperature, corroborating some previous studies.
Congenital fibrosis of the extraocular muscles maps to the centromeric region of human chromosome 12 in multiple families (1994)

Congenital fibrosis of the extraocular muscles (CFEOM) is an autosomal dominant, ocular disorder characterized by congenital, non-progressive bilateral ptosis and external ophthalmoplegia with a compensatory backward tilt of the head. The pathophysiology of this disorder is unknown and it is unclear if it has a primary neurogenic or myopathic etiology. Postmortem examination of one affected individual reveals normal brainstem, cranial nerves, and non-fibrotic extraocular muscle (EOM). EOM biopsies of several other affected individuals contain relatively normal fibers interspersed in connective tissue, possibly representing normal tendinous insertions. We recently reported linkage of this disease in two unrelated families to markers in the centromeric region of human chromosome 12. D12S59 did not recombine with the disease giving a two-point lod score of 12.5 ({theta}=0.00) while D12S87 and D12S85 flank the CFEOM locus with two-point lod scores of 8.9 ({theta}=0.03) and 5.4 ({theta}=0.03), respectively. Recent experiments with two additional families indicate that the disease in all four kindreds maps to the same locus. The use of several new markers has allowed us to identify a new flanking marker (CHLC, GATA5A09) reducing the size of the critical region to approximately 3.7 cM. Furthermore, D12S331 and D12S345 are nonrecombinant and apparently within the interval D12S87-GATA5A09.
A contribution to hot tearing in the continuous casting process (2007)

Hot tearing close to the solidus temperature occurs in continuous casting of steels. Four hot tearing criteria from the literature are reviewed and assessed against laboratory tests. Based on a critical strain criterion, an accumulated strain approach is introduced and critical values are determined by laboratory experiments.
A novel combined multi-battery dataset based approach for enhanced prediction accuracy of data driven prognostic models in capacity estimation of lithium ion batteries (2021)

To ensure smooth and reliable operations of battery systems, reliable prognosis with accurate prediction of State of Health of lithium ion batteries is of utmost importance. However, battery degradation is a complex challenge involving many electrochemical reactions at anode, separator, cathode and electrolyte/electrode interfaces. Also, there is significant effect of the operating conditions on the battery degradation. Various machine learning techniques have been applied to estimate the capacity and State of Health of lithium ion batteries to ensure reliable operation and timely maintenance. In this paper, we study the Gaussian Process Regression (GPR) and Support Vector Machine (SVM) model-based approaches in estimating the capacity and State of Health of batteries. Battery capacity and State of Health estimations are carried out using GPR and SVM models and the predictions comparatively studied for accuracy based on RMSE values. The prediction accuracy is further compared with respect to single sensor and multi sensor data. Further, a combined multi battery data set model is used to improve the prediction accuracy. Combining the data of multiple batteries with similar operating conditions for training a model resulted in higher prediction accuracy.
Evoked Acoustic Emission: Clinical Application (1985)

Stimulated acoustic emissions were recorded in response to tonal stimuli at 60 dB p.e. SPL in a small group of normal-hearing adults. Power spectral analysis reveals that the evoked activity from each ear contains energy in preferential frequency bands and the change of stimulus frequency has only a minor effect on the power spectra, i.e. the maximum jumps from one spectral peak to another. Experiments with deconvolution demonstrate that the emission generating system at least at a fixed intensity can be regarded as being linear and characterized by its impulse response which is similar to the emission evoked by click stimuli. It is concluded that significant information is obtained by the click rather than by the tonal stimuli. The click-evoked emissions were also recorded from both ears in a consecutive series of 100 full-term and otherwise normal babies 2-4 days after birth. The emission amplitudes were of the same order of magnitude as those previously found in normal-hearing adults. Cross-correlation analysis was performed in order to evaluate reproducibility and the combination of amplitudes and correlation coefficients from supra-threshold recordings and the no-stimulus recordings reveals presence of a true emission from all ears tested. It is concluded that the cochlear echo can be recorded in normal-hearing newborns with an extremely low rate of type I errors.
Deep‐brain three‐photon microscopy excited at 1600 nm with silicone oil immersion (2019)

Three-photon microscopy excited at the 1700-nm window (roughly covering 1600-1840 nm) is especially suitable for deep-brain imaging in living animals. To match the brain refractive index, D<sub>2</sub> O has been exclusively used as the immersion medium. However, the hygroscopic property of D<sub>2</sub> O leads to a decrease of transmittance of the excitation light and as a result a decrease in three-photon signals over time. Solutions such as replacing D<sub>2</sub> O from time to time, wrapping both the objective lens and the immersion D<sub>2</sub> O, and sealing D<sub>2</sub> O with paraffin liquid have all been demonstrated, which add to the system complexity. Based on our recent characterization of immersion oils, we propose using silicone oil as a potential alternative to D<sub>2</sub> O for deep-brain imaging. Excited at 1600 nm, our comparative deep-brain imaging using both D<sub>2</sub> O and silicone oil immersion show that silicone oil immersion yields 17% higher three-photon signal in third-harmonic generation imaging within the white matter. Besides, silicone oil immersion also enables three-photon fluorescence imaging of vasculature up to 1460 μm (mechanical depth) into the mouse brain in vivo acquired at 2 seconds/frame. Together with the nonhygroscopic physical property, silicone oil is promising for long-span three-photon brain imaging excited at the 1700-nm window.
Harnessing the natural inhibitory domain to control TNFα Converting Enzyme (TACE) activity in vivo (2016)

Dysregulated activity of A Disintegrin And Metalloproteinase 17 (ADAM17)/TNFα Converting Enzyme (TACE) is associated with inflammatory disorders and cancer progression by releasing regulatory membrane-tethered proteins like TNFα, IL6R and EGFR ligands. Although specific inhibition of TACE is thought to be a viable strategy for inflammatory disorders and for malignancies treatment, the generation of effective inhibitors in vivo has been proven to be challenging. Here we report on the development of a protein inhibitor that leverages the endogenous modulator of TACE. We have generated a stable form of the auto-inhibitory TACE prodomain (TPD), which specifically inhibits in vitro and cell-surface TACE, but not the related ADAM10, and effectively modulated TNFα secretion in cells. TPD significantly attenuated TACE-mediated disease models of sepsis, rheumatoid arthritis (RA) and inflammatory bowel disease (IBD), and reduced TNFα in synovial fluids from RA patients. Our results demonstrate that intervening with endogenous ADAM sheddase modulatory mechanisms holds potential as a general strategy for the design of ADAM inhibitors.
Quantification of renal steatosis in type II diabetes mellitus using dixon‐based MRI (2016)

Renal lipid content can be measured noninvasively using Dixon-based MRI and may be increased in subjects with DM2 compared to those without DM2. J. Magn. Reson. Imaging 2016;44:1312-1319.
Definition of Master Key between PANA Client and Enforcement Point (2010)

This document defines a master key used between a client of the Protocol for carrying Authentication for Network Access (PANA) and an enforcement point, for bootstrapping lower-layer ciphering.The master key is derived from the Master Session Key of the Extensible Authentication Protocol as a result of successful PANA authentication.The master key guarantees cryptographic independence among enforcement points bootstrapped from PANA authentication across different address families.
Degradation of λ-carrageenan by Pseudoalteromonas carrageenovora λ-carrageenase: a new family of glycoside hydrolases unrelated to κ- and ι-carrageenases (2007)

Carrageenans are sulfated galactans found in the cell walls of red seaweeds. They are classified according to the number and the position of sulfate ester groups. lambda-Carrageenan is the most sulfated carrageenan and carries at least three sulfates per disaccharide unit. The sole known depolymerizing enzyme of lambda-carrageenan, the lambda-carrageenase from Pseudoalteromonas carrageenovora, has been purified, cloned and sequenced. Sequence analyses have revealed that the lambda-carrageenase, referred to as CglA, is the first member of a new family of GHs (glycoside hydrolases), which is unrelated to families GH16, that contains kappa-carrageenases, and GH82, that contains iota-carrageenases. This large enzyme (105 kDa) features a low-complexity region, suggesting the presence of a linker connecting at least two independent modules. The N-terminal region is predicted to fold as a beta-propeller. The main degradation products have been purified and characterized as neo-lambda-carratetraose [DP (degree of polymerization) 4] and neo-lambda-carrahexaose (DP6), indicating that CglA hydrolyses the beta-(1-->4) linkage of lambda-carrageenan. LC-MALLS (liquid chromatography-multi-angle laser light scattering) and (1)H-NMR monitoring of the enzymatic degradation of lambda-carrageenan indicate that CglA proceeds according to an endolytic mode of action and a mechanism of inversion of the anomeric configuration. Using 2-aminoacridone-labelled neo-lambda-carrabiose oligosaccharides, in the present study we demonstrate that the active site of CglA comprises at least 8 subsites (-4 to +4) and that a DP6 oligosaccharide binds in the subsites -4 to +2 and can be hydrolysed into DP4 and DP2.
Spatial filtering of a six-wavelength DBR-RW laser in a MOPA system (2021)

Lasing emission at multiple wavelengths can be used in different sensing applications and in optical telecommunication. In this work, we report a six-wavelength distributed Bragg reflector (DBR) laser, emitting around 976 nm with six ridge waveguide (RW) structures, where individual DBR gratings are combined into a common front section. These six elements are individually addressable and biased one at a time for individual wavelength selection. The drawback of this RW combination is observable in spatial characteristics where higher-order modes are supported. We addressed this issue by using a master oscillator power amplifier (MOPA) system that combines the six-wavelength MO laser with a tapered PA. Through this configuration, the PA acts as a spatial filter of the MO beam, providing a nearly diffraction-limited beam with <i>M</i>1/<i>e</i><sup>2</sup>2<1.5. In addition, the described MOPA system provides output powers around 4 W with spectral single-mode operation, with up to 9.36 nm of thermal wavelength tuning. We believe that the described MOPA configuration can be used in different applications, such as absorption spectroscopy.
Task-Level Dexterous Manipulation With Multifingered Hand Under Modeling Uncertainties (2021)

Abstract This article presents an approach to efficiently control grippers/multifingered hands for dexterous manipulation according to a task, i.e., a predefined trajectory in the object space. The object motion is decomposed using a basis of predefined object motions equivalent to object-level coordinate couplings and leading to the definition of the task-level space. In the proposed approach, the decomposition of the motion in the task space is associated with a robust control design based on linear matrix inequalities (LMIs) and bilinear matrix inequalities (BMIs). Eigenvalue placement ensures the robustness of the system to geometric uncertainties and eigenvector placement decouples the system according to task specifications. A practical evaluation of the proposed control strategy is provided with a two-fingers' and six degrees-of-freedom robotic system manipulating an object in the horizontal plane. Results show a better trajectory tracking and the robustness of the control law according to geometric uncertainties and the manipulation of various objects.
Localized radiation grafting of flame retardants to poly(ethylene terephthalate). I. Bromine‐containing monomers (1977)

Abstract Vinyl bromide was used as a model for bromine‐containing flame retardants in developing methodology for localizing flame retardants either on the surface of the filament, uniformly throughout it, or predominantly at the core. SEM–x‐ray microprobe techniques were used in the verification of the location of the flame retardant in the filament. The flame retardance efficiency of PVBr was then correlated with its location in the filament. Grafting other bromine‐containing flame retardants showed a wide range of efficiencies which depended not only upon the location of the grafting within the filament but also upon the structure of the compound. For the various bromine homopolymer grafts, the apparent thermal stability of the graft and its flame retardance efficiency may be simply related to the alpha aliphatic hydrogen‐to‐bromine ratio. The lower this ratio is, the higher the efficiency. VBr copolymers and terpolymers showed wider variation in flame retardance efficiencies. This is attributed to large variations in melt viscosity of the different grafted materials. The grafts showed only small changes in their melting points and minimal changes in tenacity and stiffness. However, grafting induced large increases in the elongation.
Notes- Oxidation of Hindered Phenols. X. Effect of 4-Substituents Upon the Behavior of 2,6-Di-t-butylphenoxy Radicals (1960)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNotes- Oxidation of Hindered Phenols. X. Effect of 4-Substituents Upon the Behavior of 2,6-Di-t-butylphenoxy RadicalsClinton Cook and Niles GilmourCite this: J. Org. Chem. 1960, 25, 8, 1429–1431Publication Date (Print):August 1, 1960Publication History Published online1 May 2002Published inissue 1 August 1960https://pubs.acs.org/doi/10.1021/jo01078a036https://doi.org/10.1021/jo01078a036research-articleACS PublicationsRequest reuse permissionsArticle Views208Altmetric-Citations32LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
New Synthesis of Isoquinoline and 3,4-Dihydroisoquinoline Derivatives (2006)

Abstract A simple and efficient synthesis of isoquinoline and 3,4-dihydroisoquinoline derivatives is described. 1-Alkyl(or aryl)isoquinoline and 1-isoquinolinamine derivatives were obtained by intramolecular cyclization of 2-(2-methoxyethenyl)benzonitriles initiated by the addition of alkyl(or aryl)lithiums and lithium dialkylamides to the nitrile carbons, respectively. Synthesis of 4-aryl-3,4-dihydroisoquinolines was achieved by reactions of 2-(1-arylethenyl)benzonitriles with organolithiums, followed by aqueous workup. Treatment of the reaction mixtures with electrophiles prior to aqueous workup allowed the synthesis of 4,4-disubstituted 3,4-dihydroisoquinolines.
An Analysis of Urban School Leaders' Role in Community Support and Involvement (2017)

While school systems have the arduous task of educating a plethora of diverse students from different backgrounds and social economic status, the task is multifaceted. Epstein (1995) argued that to successfully meet the goal of improving education for all children, there must be considerably more involvement from parents, the community, and other stakeholders working together to promote the success of all students. That is, "students learn more and succeed at higher levels when home, school, and community work together to support students' learning and development" (Epstein & Sanders, 2006, p. 87). To meet the needs of such diverse students, their families, other administrators, and faculty (i.e., school community), school leaders, according to Green (2013, p. 14), must engage in several processes: (1) have knowledge of the emerging issues and trends that can potentially impact the school community; (2) be able to recognize the need to involve stakeholders in school decision-making; (3) assess whether they are highly visible; (4) assess whether they are actively involved; (5) assess their effectiveness in communicating with the larger community; (6) assess whether they give credence to individuals and groups whose values and opinions may conflict with theirs; and (7) assess whether they are recognizing and valuing diversity. In essence, these factors have an impact on the organizational structure of the school, influencing a collaborative culture of student, faculty, parental, and stakeholder decision-making processes (Wagner, 2007).
The filaricidal activity of some derivatives of N-[2-(4-thiazolyl)benzimidazol-5-yl]benzamide against Brugia pahangi adults. (1983)

A series of analogues of N-[2-(4-thiazolyl)benzamidazol-5-yl]benzamide with halogen substituents on the benzamide ring was tested for activity against adult Brugia pahangi in the peritoneal cavities of jirds. None of the chloro, bromo or iodo analogues was active at 5 x 100 mg/kg by subcutaneous injection. The 2-fluoro, 3-fluoro and 4-fluoro analogues showed greater activity than the parent compound and the 2,5-difluoro analogue had the same activity as the parent. The 3-fluoro, 4-fluoro and 2,5-difluoro analogues were not active in cats treated per os with 5 x 50 mg/kg.
Optical rotatory dispersion and absolute configuration of some long-chain hydroxy acids (1967)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOptical rotatory dispersion and absolute configuration of some long-chain hydroxy acidsThomas H. Applewhite, Ronald G. Binder, and William GaffieldCite this: J. Org. Chem. 1967, 32, 4, 1173–1178Publication Date (Print):April 1, 1967Publication History Published online1 May 2002Published inissue 1 April 1967https://pubs.acs.org/doi/10.1021/jo01279a071https://doi.org/10.1021/jo01279a071research-articleACS PublicationsRequest reuse permissionsArticle Views105Altmetric-Citations18LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Biodegradable composition of poly(lactic acid) from renewable wood flour (2015)

Maleic anhydride-grafted poly(lactic acid) (PLA-g-MAH) was prepared by blending with wood flour (WF). The effect of MAH and WF inclusion on the mechanical and thermal properties of the composites was examined. PLA-g-MAH/WF had optimum tensile properties compared with PLA/WF. Scanning electron microscopic images indicated poor interfacial adhesion of the PLA/WF. It was enhanced after MAH was grafted onto PLA; the PLA-g-MAH/WF showed excellent compatible morphology. Results also revealed that the biodegradation of PLA and PLA-g-MAH was improved with increasing of WF content.
Enantioselective Synthesis ofanti-β-Hydroxy-α-amido Esters via Transfer Hydrogenation (2010)

The asymmetric transfer hydrogenation of α-amido-β-keto esters to provide the corresponding anti-β-hydroxy-α-amido esters in good to excellent yields, diastereoselectivity, and enantioselectivity is reported. The procedure is operationally simple, and delicate handling of the catalyst is not necessary.
Uncorrelated multiple conductive filament nucleation and rupture in ultra-thin high-κ dielectric based resistive random access memory (2011)

Resistive switching in transition metal oxides could form the basis for next-generation non-volatile memory (NVM). It has been reported that the current in the high-conductivity state of several technologically relevant oxide materials flows through localized filaments, but these filaments have been characterized only individually, limiting our understanding of the possibility of multiple conductive filaments nucleation and rupture and the correlation kinetics of their evolution. In this study, direct visualization of uncorrelated multiple conductive filaments in ultra-thin HfO2-based high-κ dielectric resistive random access memory (RRAM) device has been achieved by high-resolution transmission electron microscopy (HRTEM), along with electron energy loss spectroscopy (EELS), for nanoscale chemical analysis. The locations of these multiple filaments are found to be spatially uncorrelated. The evolution of these microstructural changes and chemical properties of these filaments will provide a fundamental understanding of the switching mechanism for RRAM in thin oxide films and pave way for the investigation into improving the stability and scalability of switching memory devices.