gebhart/patrepeval huggingface dataset:
Synthetic aperture source localization (2019)

Abstract Many state-of-the-art methods in source localization require large numbers of sensors and perform poorly or require additional sensors when emitters of interest transmit highly correlated waveforms. We present a new source localization technique which employs a cross correlation measure of the time difference of arrival (TDOA) for signals recorded at two separate platforms, at least one of which is in motion. This data is backprojected through a process of synthetic aperture source localization (SASL) to form an image of the locations of the emitters in a region of interest (ROI) This method has the advantage of not requiring any a priori knowledge of the number of emitters in the scene. Nor does it rest on an ability to identify regions of the data which come from individual emitters, though if this capability is present it may improve image quality. We demonstrate that this method is capable of localizing emitters which transmit highly correlated waveforms, though complications arise when several such emitters are present in the scene. We discuss these complications and strategies to mitigate them.
Heart sound segmentation algorithm based on instantaneous energy of electrocardiogram (2003)

This paper presents an algorithm to detect the first heart sound (Si) and second heart sound (S2). The algorithm utilizes instantaneous energy of electrocardiogram (ECG) to estimate the presence of S1 and S2. Thus, heart sound segmentation can be done as it is essential in the automatic diagnosis of heart sounds. The instantaneous energy of ECG is performed to verify the occurrence of S1 and S2 as it is widely accepted pathologically that phonocardiogram (PCG) and electrocardiogram (ECG) are two noninvasive source of information depicting the cardiac activity. The ECG is a surface measurement of the electrical potential generated by electrical activity in cardiac tissues. Meanwhile, PCG is the graphical representation of the heart sound produced by the heart. The algorithm was tested for 210 cardiac cycles of heart sound and ECG recorded from patients from normal and abnormal simultaneously.
Supplementary Table 10_Pro metastatic pathways identified by classification analysis from A Rare Subset of Primary Tumor Cells with Concomitant Hyperactivation of Extracellular Matrix Remodeling and dsRNA-IFN1 Signaling Metastasizes in Breast Cancer (2023)

&lt;p&gt;Supplementary Table reporting the Pro metastatic pathways identified by classification analysis&lt;/p&gt;
[Implantation of Clostridium difficile in infants during antibiotherapy]. (1987)

In the adults, it is known that antibiotics allow colonization by C. difficile and its multiplication, in infants this facts is discussed. To study the influence of antibiotic treatment on the colonization of infants' intestinal tract by C. difficile, we searched this bacteria twice a week in hospitalized newborns since their birth. The population was divided in 2 groups: one never received any antibiotic, the other was treated with beta-lactams. C. difficile was isolated on appropriated selective media, and identified by biochemical and enzymatic characters. The antimicrobial susceptibility of the isolated strains was determined by broth dilution method and by broth disk-elution method. In the 2 groups the results did not significantly differ: the colonization rates are 41% in the treated group and 46% in the untreated one. The susceptibility of the strains to the tested antibiotics was similar in the 2 groups. In the environmental and dietetic conditions of our study, the infants' colonization by C. difficile seems to be independent of the antibiotic treatment.
Preparation of Core‐Sheath Composite Nanofibers by Emulsion Electrospinning (2006)

Abstract Summary: Uniform core‐sheath nanofibers are prepared by electrospinning a water‐in‐oil emulsion in which the aqueous phase consists of a poly(ethylene oxide) (PEO) solution in water and the oily phase is a chloroform solution of an amphiphilic poly(ethylene glycol)‐poly( L ‐lactic acid) (PEG‐PLA) diblock copolymer. The obtained fibers are composed of a PEO core and a PEG‐PLA sheath with a sharp boundary in between. By adjusting the emulsion composition and the emulsification parameters, the overall fiber size and the relative diameters of the core and the sheath can be changed. A mechanism is proposed to explain the process of transformation from the emulsion to the core‐sheath fibers, i.e., the stretching and evaporation induced de‐emulsification. In principle, this process can be applied to other systems to prepare core‐sheath fibers in place of concentric electrospinning and it is especially suitable for fabricating composite nanofibers that contain water‐soluble drugs. Schematic mechanism for the formation of core‐sheath composite fibers during emulsion electrospinning. image Schematic mechanism for the formation of core‐sheath composite fibers during emulsion electrospinning.
Characterization of measurement system for high-precision oscillator measurements (2017)

Temperature stability of a high-precision oscillator is characterized by measurements in a temperature chamber. Two time constants are measured for a given temperature of the chamber: (i) time required for the silicon to reach the steady-state temperature obtained by measuring the time-domain voltage response of the on-chip temperature sensor; (ii) time required for the oscillator circuit to reach the steady-state frequency obtained by measuring the oscillator frequency in the time-domain. The temperature probe for measuring the chamber temperature is characterized in terms of its response to a step in temperature. The noise performance of the measurement system is characterized based on Allan deviation.
Binding energy of the impurity level in theGa1−xAlxAs−GaAs−Ga1−yAlyAssuperlattice (1983)

The binding energy of the first impurity level in the ${\mathrm{Ga}}_{1\ensuremath{-}x}{\mathrm{Al}}_{x}\mathrm{A}\mathrm{s}\ensuremath{-}\mathrm{G}\mathrm{a}\mathrm{A}\mathrm{s}\ensuremath{-}{\mathrm{Ga}}_{1\ensuremath{-}y}{\mathrm{Al}}_{y}\mathrm{As}$ superlattice is investigated by considering a variational problem in a finite quantum well with a hydrogenic impurity potential. For the case of the finite well, we first deal with the dependency of the binding energy on the impurity position and on the barrier heights of the quantum well. Each barrier height is independently changed in the present study. It is pointed out that the binding energy is underestimated when one employs an infinite barrier height to represent the quantum well. The electron distribution in the superlattice depending on various impurity positions is also discussed.
ChemInform Abstract: (RECL2(NO)2(SB(C6H5)3)2); SYNTHESIS, CRYSTAL STRUCTURE, INFRARED AND ANTIMONY‐121 MOESSBAUER SPECTRUM (1983)

Abstract Die Titelverbindung (I) entsteht bei der Einwirkung von überschüssi‐ ‐ gem Triphenylantimon auf ReCl 3 (NO), in Dichlormethan‐Suspension.
Integrating Student and Program Assessment with a Teacher Candidate Portfolio (2009)

https://scholarlycommons.pacific.edu/provost-facbooks/1003/thumbnail.jpg
BONE MARROW PROCESSING IN ABO-INCOMPATIBLE BONE MARROW TRANSPLANTATION USING COBE SPECTRA CELL SEPARATOR (2006)

血液型不適合骨髄移植を行う際は, 輸注に伴う有害事象を避けるため, 骨髄液中の赤血球・血漿除去が必要である. 今回われわれは, 血液成分分離装置COBE Spectra により, 骨髄液から単核球を分離することで, 骨髄細胞濃縮を行った血液型不適合骨髄移植20例において, その有用性について検討した. COBE Spectra を用いた骨髄濃縮により, 赤血球量は98.4%除去され, 最終赤血球量は4.2±2.4mlであった. 有核細胞回収率は34.0±8.38%, CD34陽性細胞回収率は112.3±36.3%であった. 20症例全例で, 移植後の溶血反応および生着不全は認めず, 移植後造血回復は速やかであった. COBE Spectra を用いることで, 清潔な無菌閉鎖回路内において骨髄濃縮が可能となり, 処理時間も短縮された. 種々の細胞免疫療法の用途で広く普及しているCOBE Spectra を用いた骨髄濃縮法は, 血液型不適合骨髄移植における骨髄濃縮の標準的方法として有用であると考えられた.
Analysis and Measurement of Glue‐Spall Stresses in Glass‐Epoxy Bonds (1982)

An approximate analysis is presented of the glue‐spall stresses introduced by an organic sealant in the glass substrate to which it adheres. The results given by this analysis are compared with those obtained by the finite element method, as well as with the photoelastic measurements in glass at T=25 to −78°C during cooling. Good agreement is found between theory and experiment, if proper account is taken of the stress release due to creep of the organic sealant. Methods for minimizing glue‐spall stresses are outlined.
Demonstration of SpeakQL (2019)

In this demonstration, we present SpeakQL, a speech-driven query system and interface for structured data. SpeakQL supports a tractable and practically useful subset of regular SQL, allowing users to query in any domain with unbounded vocabulary with the help of speech/touch based user-in-the-loop mechanisms for correction. When querying in such domains, automatic speech recognition introduces countless forms of errors in transcriptions, presenting us with a technical challenge. We characterize such errors and leverage our observations along with SQL's unambiguous context-free grammar to first correct the query structure. We then exploit phonetic representation of the queried database to identify the correct Literals, hence delivering the corrected transcribed query. In this demo, we show that SpeakQL helps users reduce time and effort in specifying SQL queries significantly. In addition, we show that SpeakQL, unlike Natural Language Interfaces and conversational assistants, allows users to query over any arbitrary database schema. We allow the audience to explore SpeakQL using an easy-to-use web-based interface to compose SQL queries.
Developmental changes in purine nucleotide metabolism in cultured rat astroglia (1995)

The present study was conducted in order to clarify the role of the glia in brain purine metabolism. This, in connection with the clarification of the etiology of the neurological manifestations associated with some of the inborn errors of purine metabolism in man. Purine nucleotide content, the capacity for de novo and salvage purine synthesis and the activity of several enzymes of purine nucleotide degradation, were assayed in primary cultures of rat astroglia in relation to culture age. The capacity of the intact cells to produce purine nucleotides de novo exhibited a marked decrease with the culture age, but the activity of hypoxanthine-guanine phosphoribosyltransferase (HGPRT), catalyzing salvage nucleotide synthesis, increased. Aging was also associated with a marked increase in the activity of the degradation enzymes AMP deaminase, purine nucleoside phosphorylase (PNP) and guanine deaminase (guanase). The activity of adenosine deaminase and of AMP-5'-nucleotidase, increased markedly during the first 17 days in culture, but decreased thereafter. The results indicate that purine nucleotide metabolism in the cultured astroglia is changing with aging to allow the cells to maintain their nucleotide pool by reutilization of preformed hypoxanthine, rather than by de-novo production of new purines. Aging is also associated with increased capacity for operation of the adenine nucleotide cycle, contributing to the homeostasis of adenine nucleotides and to the energy charge of the cells. In principle, the age-related alterations in purine metabolism in the astroglia resemble those occurring in the maturating neurons, except for the capacity to produce purines de novo, which exhibited inverse trends in the two tissues. However, in comparison to the neurons, the cultured astroglia possess the capacity for a more intensive metabolism of purine nucleotides.
Fe-N-C PGM-Free ORR Catalysts: An Investigation of the Source of Observed Redox Peaks and Their Significance to Catalysis (2022)

Iron-based platinum group metal free (PGM-free) carbonaceous catalysts of a type commonly called “Fe-N-C” have high activity metals in the oxidation reduction reaction (ORR) in acid electrolytes. However, the durability of Fe-N-C catalysts is typically low. One puzzling feature of Fe-N-C catalysts is that they often – but not always – exhibit redox peaks near the expected potential of Fe 2+ à Fe 3+ + e - (0.77 V vs. SHE). It has been observed that the absence of these peaks is correlated with improved catalytic performance. While the source of these peaks has not been identified rigorously as iron redox, it has been observed that the peaks appear in the presence of iron and do not appear in voltammograms of either N-C substrate alone or cobalt catalyst analogs (Co-N-C). Furthermore, the redox potential of these peaks shifts when the electrolyte is changed from sulfuric acid to perchloric acid, whereas the halfwave potential of the ORR does not change. What, then, is the source of these peaks? And does the redox event have significance to the catalytic mechanism? The study reported here investigates the effect of a series of acid electrolytes on the observed redox peaks, showing a progressive shift to lower potentials in perchloric, sulfuric, and phosphoric acids. Furthermore, these peaks are demonstrated to be absent in the case of N-C substrate alone. Addition of iron salts to the electrolytes results in the appearance of peaks in the voltammograms of N-C, with associated changes in the capacitance, indicating that the source of the peaks is surface-adsorbed iron salts. Therefore, the appearance of redox peaks is an indicator of the degradation of the catalyst and no change in the halfwave potential would be expected, as the adsorbed salts are not catalytically active.
Lateral drilling and completion technologies for shallow-shelf carbonates of the Red River and Ratcliffe Formations, Williston Basin. Topical report, July 1997 (1998)

Luff Exploration Company (LEC) focused on involvement in technologies being developed utilizing horizontal drilling concepts to enhance oil-well productivity starting in 1992. Initial efforts were directed toward high-pressure lateral jetting techniques to be applied in existing vertical wells. After involvement in several failed field attempts with jetting technologies, emphasis shifted to application of emerging technologies for drilling short-radius lateral in existing wellbores and medium-radius technologies in new wells. These lateral drilling technologies were applied in the Mississippi Ratcliffe and Ordovician Red River formations at depths of 2,590 to 2,890 m in Richland County, MT; Bowman County, ND; and Harding County, SD. In theory, all of the horizontal drilling techniques explored in this project have merit for application fitting specific criteria. From a realistic point of view, the only relatively trouble-free, adequately-proven technology employed was the medium-radius steered motor/MWD technology. The slim-tool steered motor/MWD re-entry technology has been used extensively but appears to still be significantly in developmental stages. This technology will probably always be more troublesome than the technology used to drill new wells because the smaller diameter required for the tools contributes to both design and operational complexities. Although limited mechanical success has been achieved with some of the lateral jetting technologies and the Amoco tools, their predictability and reliability is unproven. Additionally, they appear to be limited to shallow depths and certain rock types. The Amoco technology probably has the most potential to be successfully developed for routinely reliable, field applications. A comparison of the various horizontal drilling technologies investigated is presented.
4-Trifluoromethylumbelliferyl-β-D-Galactopyranoside: Its synthesis and Application as the Fluorigenic Substrate of β-GalactosidaseE. Colifor Screening Monoclonal Antibodies by Immunosorbent Elisa (1988)

Abstract Stereoselective method for high-yield synthesis of 4-trifluoromethylumbelliferyl-β-D-galactopyrano-side - fluorigenic substrate for β-galactosidase E. coli, as enzyme label for ELISA, has been developed. The substrate is readily available in pure and stable form, nonfluorescent under the detection conditions and has no significant nonenzymatic degradation to fluorescent products. Compared to the well known 4-me-thylumbelliferone (λex = 360 nm, λem = 450 nm), 4-trifluoromethylumbelliferone has a slightly large Stokes shift (λex = 400 nm, λem = 500 nm), a longer excitation wavelength and emits green fluorescence through the enzymatic reaction. In the present ELISA we used 4-trifluoromethylumbelliferyl-β-D-galactopy-ranoside as sensitive enzyme substrate for rapid and visual screening of desired hybridoma clones producing monoclonal antibodies. With this immunoassay we succesfully selected antiperoxidase monoclonal antibodies which inhibited peroxidase activity.
ROLE OF THE HIGH-AFFINITY PENTASACCHARIDE IN HEPARIN ACCELERATION OF ANTITHROMBIN III INHIBITION OF THROMBIN AND FACTOR Xa (1987)

The high-affinity heparin pentasaccharide (H5) and an 8000 Mr high-affinity heparin (H26) have been compared with respect to their interaction with antithrombin III (AT) and their accelerating effect on AT inhibition of thrombin (T) and factor Xa by rapid kinetic and equilibrium binding studies at pH 7.4, 25°C. Kds of .068 μM at I 0.15 and 0.57 μM at I 0.3 were determined for tne AT-H5 interaction, which were 5 and 2.5-fold weaker, respectively, than affinities determined for H26. Comparison of the kinetics of binding of H5 and H26 to AT at I 0.15 under pseudofirst order conditions ([H]o&gt;&gt; [AT]o) demonstrated a saturable dependence of the observed rate constant for both reaction with indistinguishable limiting rate constants of 700 +/-120 s-1 and 520 +/-90 s-1 , but somewhat different Kds for the initial binding interaction of 20 and 29 μM for H5 and H26, respectively. These results indicate that H5 induces the same conformational change in AT as the larger heparin, but that the rate of reversal of this conformational change is greater for H5 which is the basis for its weaker AT affinity. Bimolecular rate constants for neutralization of factor Xa and thrombin by AT-H5 and AT-H26 complexes were determined by p-aminobenzamidine displacement under pseudo-first order conditions([AT-H] &gt;&gt; [T]o or [Xa]o). I-in-dependent values of .62 μM-1 s-1 were obtained for Xa inhibition by AT-H5 at I 0.15 and 0.3, compared to I-dependent values of 1.4 and 0.91 μM-1 s-1 for AT-H26. For thrombin inhibition by AT-H5, and I-independent enhancement of 1.6-fold in the bimolecular rate constant from .0098 to .016 μM-1 s-1 was observed, in sharp contrast to the marked I-independent enhancement by AT-H26 of the bimolecular rate constant ranging from 4000 to 200-fold at I 0.15 and 0.3, respectively. These results are consistent with a primary ionic strength-independent contribution of the AT conformational change to heparin enhancement of factor Xa but not thrombin neutralization by AT, with an ionic strength-dependent component for both reactions, compatible with a differential role for a protease-heparin interaction. Supported by grant HL-30237
RSSI based adaptive indoor location tracker (2017)

Due to the impracticality of the Global Navigation Satellite Systems (GNSS) in the indoor locations, Wireless Network based Systems (WNS) are widely used for the indoor location estimation techniques. Compared to various other localization methods, the Received Signal Strength Indicator (RSSI) based techniques are highly appreciated because of their minimal complexity. Thus based on these, a generic application has been developed to track the location of any person in any area, with adequate Access Points (AP’s), by comparing the Received Signal Strength (RSS) at his/her position with the already stored set of RSS from the dataset. To find out the best possible match from a group of possible locations in the dataset, the Root Mean Square Error (RMSE) method has been used, which has less complexity and more accuracy over its alternative methods. The unique features of this application includes the dynamic database which can be conveniently updated whenever needed, live input of any indoor location map through camera and immediate creation of a new dataset, allowing the application to be used by any person in any area.
Unraveling the relationship between microbial translocation and systemic immune activation in HIV infection (2014)

Chronic immune activation is a key factor in HIV-1 disease progression. The translocation of microbial products from the intestinal lumen into the systemic circulation occurs during HIV-1 infection and is associated closely with immune activation; however, it has not been determined conclusively whether microbial translocation drives immune activation or occurs as a consequence of HIV-1 infection. In an important study in this issue of the JCI, Kristoff and colleagues describe the role of microbial translocation in producing immune activation in an animal model of HIV-1 infection, SIV infection of pigtailed macaques. Blocking translocation of intestinal bacterial LPS into the circulation dramatically reduced T cell activation and proliferation, production of proinflammatory cytokines, and plasma SIV RNA levels. This study directly demonstrates that microbial translocation promotes the systemic immune activation associated with HIV-1/SIV infection.
Low VWF levels in children and lack of association with bleeding in children undergoing tonsillectomy (2020)

von Willebrand disease is a common bleeding disorder, but diagnosis can be difficult in young children who have not had bleeding challenges. We sought to evaluate the correlation between bleeding and von Willebrand factor (VWF) levels in children undergoing surgical challenge with tonsillectomy. Children ages 0 to 18 undergoing tonsillectomy without a personal or family history of bleeding were enrolled prospectively following informed consent and institutional review board approval. VWF levels were obtained at the time of surgery. VWF antigen (VWF:Ag) and VWF activity (VWF:GPIbM) were tested via enzyme-linked immunosorbent assay. Bleeding score was calculated using the International Society of Hematology bleeding assessment tool (BAT). Surgical and postoperative bleeding were determined using questionnaires filled out by the surgeon and patient/family. A total of 1399 subjects were enrolled with evaluable data, with a median age of 5 years. The median VWF:Ag was 85 IU/dL and the median VWF:GPIbM was 100 U/dL. Median BAT for the entire population was 0, including those with postoperative bleeding. There was no difference in VWF level between those who experienced postoperative bleeding and those who did not, with median VWF:Ag 85 vs 85 (P = .89) and mean VWF:GPIbM 98 vs 100 (P = .5). Interestingly, there was a difference in VWF levels with age, with median VWF:Ag 81 for those younger than 3 years, 82 for those 3 to 6 years, 90 for those 7 to 10 years, and 100 for those 11 to 18 years. A similar trend was noted for VWF:GPIbM. Of the 2 to 6 year olds, 5% had VWF:Ag <50, which would meet criteria for low VWF, but only 1.8% had an abnormal BAT at study entry and only 2.5% bled after surgery. Only 1 subject with low VWF had an elevated postoperative BAT >2. These data suggest that low VWF levels do not correlate with bleeding in children undergoing tonsillectomy. In addition, VWF levels outside the adult normal range in young children may be more common than previously thought and do not necessarily predict surgical bleeding.
Spectral Analysis of Signed Graphs for Clustering, Prediction and Visualization (2010)

We study the application of spectral clustering, prediction and visualization methods to graphs with negatively weighted edges. We show that several characteristic matrices of graphs can be extended to graphs with positively and negatively weighted edges, giving signed spectral clustering methods, signed graph kernels and network visualization methods that apply to signed graphs. In particular, we review a signed variant of the graph Laplacian. We derive our results by considering random walks, graph clustering, graph drawing and electrical networks, showing that they all result in the same formalism for handling negatively weighted edges. We illustrate our methods using examples from social networks with negative edges and bipartite rating graphs.