gebhart/patrepeval huggingface dataset:
<i>In Situ</i> XRD Stress Analysis during Expansion of Stents (2013)

Stents are medical implants, which are applied to keep cavities in the human body open, e.g. blood vessels. Typically they consist of tube-like grids of suitable metal alloys. Typical dimensions depend on their applications: outer diameters in the mm-range and grid bar thickness in the 100 µm range. Before implantation, stents are compressed (crimped) to allow implantation in the human body. During implantation, stents are expanded, usually by balloon catheters. Crimping as well as expansion causes high strains and high stresses locally in the grid bars. These strains and stresses are important design criteria of stents. Usually, they are calculated numerically by Finite Element Analysis (FEA) [1,2]. The XRD-sin²ψ-technique is applied for in-situ-determination of stress conditions during crimping and expansion of stents of the CoCr-alloy L-605. This provides a realistic characterization of the near-surface stress state and an evaluation of the numerical FEA results. XRD-results show an increasing compressive load stress in circumferential direction with increasing stent expansion. These findings correlate with the numerical FEA results. Further residual stresses after removing the expansion device have been measured.
The contemporary geochemistry of uranium in the Gulf of Mexico Distributive Province (1972)

This study concerned the contemporary geochemistry of uranium in the Gulf of Mexico and adjacent areas. Hundreds of samples were analyzed using the novel delayed neutron counting technique. Emphasis was placed on understanding man's effects on present day inputs and assessing the importance of various uranium sinks in the Gulf. Field and laboratory fertilizer studies indicate that (1) a linear relationship exists between phosphate and uranium in commercially processed fertilizers; (2) this linear relationship exists in the various processing steps of both the Florida and North Carolina phosphates; (3) from these linear plots 100% P₂O₅ has 380 ppm uranium, which is considerably higher than previous estimates from ore concentrations; (4) uranium enters runoff via dissolution of fertilizers as shown in weathering experiments; (5) high uranium concentrations in the Brazos River occur after early spring fertilization; (6) Ra²²⁶, a hazardous daughter product of U²³⁸, is in approximately 10% radioactive equilibrium with U²³⁸ in phosphate fertilizers; and (7) a reasonable balance exists between input and deposition when the estimated increment caused by fertilization is subtracted from the total soluble uranium input. ...
Age and Sex Normalization of Intestinal Permeability Measures for the Improved Assessment of Enteropathy in Infancy and Early Childhood (2017)

Alterations in recovery of the probes differ markedly in different epidemiologic contexts in children living in the developing world. The rate of change in the L:M-z ratio was most rapid and consistently disparate from the reference standard in the period between 6 and 9 months of age, suggesting that this is a critical period of physiologic impact of enteropathy in these populations.
23 VAGUS NERVE ACTIVITY AND CYTOKINE RESPONSIVENESS IN PATIENTS WITH RHEUMATOID ARTHRITIS. (2006)

<h3></h3> Recent literature has shown that the central nervous system can modulate the innate immune response through a rapid, local, and integrated mechanism. This pathway, termed the cholinergic anti-inflammatory pathway (CAP), acts via the vagus nerve through the neurotransmitter acetylcholine (Tracey, 2002). Activation of this pathway results in decreased proinflammatory cytokine production in in vitro experiments and in vivo models of inflammatory disease (Borovikova et al, 2000; Bernick et al, 2002). It has been observed that autonomic dysfunction develops in patients with diseases associated with cytokine excess, such as sepsis and rheumatoid arthritis (RA) (Hakala M and RK Niemela, 2000; Louthrenoo et al, 1999). However, the relationship between autonomic dysfunction and cytokine synthesis has not been explored. The purpose of this study is to explore the relationship between vagus nerve activity and cytokine synthesis in patients with RA compared to healthy subjects. A prospective observational study was performed at the North Shore-LIJ GCRC in subjects with RA and age- and sex-matched healthy volunteers (<i>n</i> = 12, 50 ± 10.9 years, <i>n</i> = 13, 42 ± 14.6, respectively). Vagus nerve activity was assessed by determining instantaneous heart rate variability (HRV) using parameters representing vagal nerve activity, including high-frequency power (HF), SDANN, and RMSSD. Blood was collected and stimulated with endotoxin and subsequently analyzed for the cytokines tumor necrosis factor (TNF) and high mobility box 1 protein (HMGB1). All measured components of HRV were attenuated in the RA subjects as compared to the healthy volunteers (HF power [msec<sup>2</sup>] = 40 ± 8.8, 410 ± 122, <i>p</i> &lt; .01, SDANN = 32 ± 4.5, 68 ± 12.9, p &lt; .05, and RMSSD = 21 ± 0.41, 57 ± 11.1, p &lt; .01, respectively). Cytokine analysis measuring serum TNF levels were attenuated in the RA group as compared to healthy volunteers (TNF [pg/mL] = 6,474 ± 2,028, 15,489 ± 1,514, p &lt; .01, respectively). This supports our hypothesis that autonomic dysfunction, as reflected by lower vagal nerve output, may contribute to underlying dysfunctional cytokine activity during chronic inflammation. (Data presented as mean ± standard error and analyzed by two-tailed Student9s t-test.) Supported by NIGMS and GCRC M01RR018535 of The Feinstein Institute for Medical Research, North Shore-LIJ Health System.
[Color Doppler imaging of central retinal artery in retinopathy of prematurity]. (2000)

Color Doppler imaging (CDI) is a noninvasive technique, combining 2-dimensional brightness-modulated (B-mode) ultrasound evaluation of eye and orbital structures, with simultaneous color-coded Doppler imaging of orbital blood flow. It has been used to characterize various ophthalmic disorders in adults. Currently there is no data describing orbital blood flow parameters in either normal children or in those with ophthalmic disease, such as the retinopathy of prematurity (ROP). We evaluated blood flow in the central retinal artery of preterm infants undergoing examination for ROP. We also investigated whether useful readings could be obtained on a consistent basis, and the reproducibility of differences in central retinal artery blood flow between subjects with and without ROP (including the influence of "plus" disease). We obtained hemodynamic readings in 43 of 46 eyes of preterm infants. 13 eyes had no signs of ROP; 18 had ROP (at least stage 1) without "plus" disease, and 12 had ROP with "plus" disease. There were no statistically significant differences in systolic blood flow velocity within the 3 groups. However the average velocity was slower in the "plus" disease group, correlating with the clinical finding of dilated and tortuous blood vessels which characterize the posterior retina of ROP eyes with "plus" disease.
Sensing Matrix Design and Sparse Recovery on the Sphere and the Rotation Group (2020)

In this article, the goal is to design deterministic sampling patterns on the sphere and the rotation group and, thereby, construct sensing matrices for sparse recovery of band-limited functions. It is first shown that random sensing matrices, which consists of random samples of Wigner D-functions, satisfy the Restricted Isometry Property (RIP) with proper preconditioning and can be used for sparse recovery on the rotation group. The mutual coherence, however, is used to assess the performance of deterministic and regular sensing matrices. We show that many of widely used regular sampling patterns yield sensing matrices with the worst possible mutual coherence, and therefore are undesirable for sparse recovery. Using tools from angular momentum analysis in quantum mechanics, we provide a new expression for the mutual coherence, which encourages the use of regular elevation samples. We construct low coherence deterministic matrices by fixing the regular samples on the elevation and minimizing the mutual coherence over the azimuth-polarization choice. It is shown that once the elevation sampling is fixed, the mutual coherence has a lower bound that depends only on the elevation samples. This lower bound, however, can be achieved for spherical harmonics, which leads to new sensing matrices with better coherence than other representative regular sampling patterns. This is reflected as well in our numerical experiments where our proposed sampling patterns perfectly match the phase transition of random sampling patterns.
Commentary Microsomal prostaglandin E synthase-1: the inducible synthase for prostaglandin E 2 (2005)

Microsomal prostaglandin E synthase-1 (mPGES-1) is an inducible enzyme that catalyzes the conversion of prostaglandin (PG)H 2 to PGE 2. Proinflammatory stimuli markedly increase levels of mPGES-1 expression both in vivo and in vitro. mPGES-1 knockout studies and animal models of inflammatory arthritis also provide a strong basis for the contribution of mPGES-1 in the increased local production of PGE 2 observed in inflammatory arthritis. The focus of this article is to review some recent advances in our understanding of mechanisms specific to the regulation of inducible mPGES-1 in inflammatory arthritis.
Characterization of a Bifidobacterium longum BORI Dipeptidase Belonging to the U34 Family (2007)

A dipeptidase was purified from a cell extract of Bifidobacterium longum BORI by ammonium sulfate precipitation and chromatography on DEAE-cellulose and Q-Sepharose columns. The purified dipeptidase had a molecular mass of about 49 kDa and was optimally active at pH 8.0 and 50 degrees C. The enzyme was a strict dipeptidase, being capable of hydrolyzing a range of dipeptides but not tri- and tetrapeptides, p-nitroanilide derivatives of amino acids, or N- or C-terminus-blocked dipeptides. A search of the amino acid sequence of an internal tryptic fragment against protein sequences deduced from the total genome sequence of B. longum NCC2705 revealed that it was identical to an internal sequence of the dipeptidase gene (pepD), which comprised 1,602 nucleotides encoding 533 amino acids with a molecular mass of 60 kDa, and thereby differed considerably from the 49-kDa mass of the purified dipeptidase. To understand this discrepancy, pepD was cloned into an Escherichia coli expression vector (pBAD-TOPO derivative) to generate the recombinant plasmids pBAD-pepD and pBAD-pepD-His (note that His in the plasmid designation stands for a polyhistidine coding region). Both plasmids were successfully expressed in E. coli, and the recombinant protein PepD-His was purified using nickel-chelating affinity chromatography and reconfirmed by internal amino acid sequencing. The PepD sequence was highly homologous to those of the U34 family of peptidases, suggesting that the B. longum BORI dipeptidase is a type of cysteine-type N-terminal nucleophile hydrolase and has a beta-hairpin motif similar to that of penicillin V acylase, which is activated by autoproteolytic processing.
Antioxidative Activity in the Pericarp and Seed of Japanese Pepper (Xanthoxylum piperitum DC) (2000)

The antioxidative activity of the dried pericarp and seed of Japanese pepper was studied. The ethyl acetate extract from the pericarp and the methanol extract from the seed showed strong antioxidative activity against linoleic acid by the ferric thiocyanate and thiobarbituric acid (TBA) methods. Japanese pepper contained 3.9 and 2.9 mg/100 g of dry weight (dw) of tocopherols in the pericarp and seed, respectively, alpha-Toc in the former constituting 82% of total tocopherol and gamma-Toc in the latter constituting 96%. Arbutin and magnoflorine were isolated as antioxidants and their chemical structures determined by instrumental analyses. The contents of arbutin evaluated as the trifluoroacetate derivative by GC-MS were 35 and 3.0 mg/100 g of dw in the pericarp and seed, respectively. Magnoflorine was present only in the seed, and not in the pericarp. Both arbutin and magnoflorine exhibited antioxidative activity against linoleic acid and radical-scavenging activity against the DPPH radical.
OVX836 a recombinant nucleoprotein vaccine inducing cellular responses and protective efficacy against multiple influenza A subtypes (2019)

Inactivated influenza vaccines (IIVs) lack broad efficacy. Cellular immunity to a conserved internal antigen, the nucleoprotein (NP), has been correlated to protection against pandemic and seasonal influenza and thus could have the potential to broaden vaccine efficacy. We developed OVX836, a recombinant protein vaccine based on an oligomerized NP, which shows increased uptake by dendritic cells and immunogenicity compared with NP. Intramuscular immunization in mice with OVX836 induced strong NP-specific CD4+ and CD8+ T-cell systemic responses and established CD8+ tissue memory T cells in the lung parenchyma. Strikingly, OVX836 protected mice against viral challenge with three different influenza A subtypes, isolated several decades apart and induced a reduction in viral load. When co-administered with IIV, OVX836 was even more effective in reducing lung viral load.
Reduction of Flap Side Edge Noise - the Blowing Flap (2005)

A technique to reduce the noise radiating from a wing-flap side edge is being developed. As an airplane wing with an extended flap is exposed to a subsonic airflow, air is blown outward through thin rectangular chord-wise slots at various locations along the side edges and side surface of the flap to weaken and push away the vortices that originate in that region of the flap and are responsible for important noise emissions. Air is blown through the slots at up to twice the local flow velocity. The blowing is done using one or multiple slots, where a slot is located along the top, bottom or side surface of the flap along the side edge, or also along the intersection of the bottom (or top) and side surfaces.
The alpha2 domain of H-2Dd restricts the allelic specificity of the murine NK cell inhibitory receptor Ly-49A. (1998)

Mouse NK lymphocytes express Ly-49 receptors, which inhibit cytotoxicity upon ligation by specific MHC I molecules on targets. Different members of the lectin-like mouse Ly-49 receptor family recognize distinct subsets of murine H-2 molecules, but the molecular basis for the allelic specificity of Ly-49 has not been defined. We analyzed inhibition of natural killing by chimeric MHC I molecules in which the alpha1, alpha2, or alpha3 domains of the Ly-49A-binding allele H-2Dd were exchanged for the corresponding domains of the nonbinding allele H-2Db. Using the Ly-49A-transfected rat NK cell line, RNK-mLy-49A.9, we demonstrated that the H-2Dd alpha2 domain alone accounts for allelic specificity in protection of rat YB2/0 targets in vitro. We also showed that the H-2Dd alpha2 domain is sufficient to account for the allele-specific in vivo protection of H-2b mouse RBL-5 tumors from NK cell-mediated rejection in D8 mice. Thus, in striking contrast to the alpha1 specificity of Ig-like killer inhibitory receptors for human HLA, the lectin-like mouse Ly-49A receptor is predominantly restricted by the H-2Dd alpha2 domain in vitro and in vivo.
Optical processing for adaptive phased-array radar (1980)

A multichannel coherent optical correlator and a noncoherent optical vector-matrix processor are described and their application to the processing of data from an adaptive phased-array radar are discussed.
Nickel‐Catalyzed Cocyclotrimerization of Arynes with Diynes; a Novel Method for Synthesis of Naphthalene Derivatives. (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
Radioimmunoassay for quantitation of 2,3,7,8-tetrachlorodibenzofuran (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRadioimmunoassay for quantitation of 2,3,7,8-tetrachlorodibenzofuranMichael I. Luster, Phillip W. Albro, Kun. Chae, Lela D. Lawson, Jean T. Corbett, and James D. McKinneyCite this: Anal. Chem. 1980, 52, 9, 1497–1500Publication Date (Print):August 1, 1980Publication History Published online1 May 2002Published inissue 1 August 1980https://pubs.acs.org/doi/10.1021/ac50059a026https://doi.org/10.1021/ac50059a026research-articleACS PublicationsRequest reuse permissionsArticle Views46Altmetric-Citations21LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Self-consistent calculations of loss-compensated fishnet metamaterials (2010)

We present a computational approach, allowing for a self-consistent treatment of three-dimensional fishnet metamaterial coupled to a gain material incorporated into the nanostructure. We show numerically that one can compensate the losses by incorporating gain material inside the fishnet structure. The pump rate needed to compensate the loss is much smaller than the bulk gain and the figure of merit $[\text{FOM}=|\text{Re}(n)/\text{Im}(n)|]$ increases dramatically with the pump rate. Transmission, reflection, and absorption data, as well as the retrieved effective parameters, are presented for the fishnet structure with and without gain material. Kramers-Kronig relations of the effective parameters are in excellent agreement with the retrieved results with gain.
Imaging in the Diagnosis, Staging, Treatment, and Surveillance of Hepatocellular Carcinoma (2003)

Imaging in the Diagnosis, Staging, Treatment, and Surveillance of Hepatocellular CarcinomaJanio Szklaruk1, Paul M. Silverman and Chusilp CharnsangavejAudio Available | Share
A detection model based on statistical against DDoS attack (2009)

A development and research for Distributed denial of service attack detection is underway. A statistical technique identified efficiently the normal packets and abnormal packets. In this paper several statistical techniques, using a mix of various offers a way to detect the attack. To verify the effectiveness of the proposed technique, it set packet filtering on router and the proposed DDoS attacks detection method on a Linux router. In result, the proposed technique detected various attacks, provided normal service mostly.
Vitamin D resistance and alopecia. A causal or casual relationship? (1985)

It is well established that the skin, after exposure to sunlight, serves as an organ for the production of the hormone cholecalciferol.<sup>1</sup>During the past 15 years, extensive research on the metabolism of vitamin D has revealed that cholecalciferol, after its formation in the skin, is transported to the liver, where it is metabolized to calcifediol (25-hydroxyvitamin D<sub>3</sub>). Calcifediol is the major circulating form of cholecalciferol and is transported to the kidney and metabolized to calcitriol (1,25-dihydroxyvitamin D<sub>3</sub>), the biologically active form of this hormone.<sup>2,3</sup> Because vitamin D is a calcium-regulating hormone, most investigators previously believed that the principal target organs for this hormone were limited to the small intestine, bone, and kidney. Indeed, these target organs contain specific cytosolic and nuclear-binding proteins that have a high affinity and low capacity for calcitriol. After this hormone enters the cell and is bound to its cytoplasmic receptor,
Engineering exotic linear and nonlinear electromagnetic responses using spatial and spatiotemporal modulation (2019)

Periodicity and modulation lie at the heart of modern electromagnetic, acoustic and mechanical engineering, dramatically altering the way in which waves interact with periodically structured media. The main idea driving the intense research into periodic systems is the fact that periodicity breaks the dependence on natural properties of constituent media and instead allows one to blend the responses of various materials and leverage their geometric shapes to obtain collective responses on demand. In the realm of electromagnetics, over the past two decades there has been an explosive surge of interest to artificially engineered time-invariant periodic structures thanks to numerous fascinating linear and nonlinear effects they enable. In this dissertation, I will present some transformative developments in the area of efficient nonlinear generation and wave mixing in thin 2D periodic structures based on multi-quantum-wells, as well as show the possibility to engineer to the great extent the dispersion topology of surface waves propagating along ideally thin conducting sheets with 1D spatial periodicity such as graphene ribbons. In parallel with the progress in obtaining desired responses in time-invariant periodic structures, significant progress is being made in applying temporal and synchronous spatial and temporal modulation to engage new degrees of freedom and extend the spectrum of achievable electromagnetic phenomena even further. In this dissertation, I will also show that spatiotemporal modulation applied to electronic networks holds a key to obtain ultrawideband and extremely compact delays far beyond those achievable in time-invariant systems. Spatiotemporal modulation also allows for all kinds of nonreciprocal devices to be seamlessly integrated in an electronic chip by overcoming the size and magnetic material incompatibility constraints. This fact holds a truly groundbreaking potential for future electronic devices and wireless systems by enabling their simultaneous transmit-and-receive operation. Finally, I will show that spatiotemporal modulation enables a direct translation of some of the most advanced and intricate concepts of condensed matter physics – topological insulators – to the realm of classical electronic circuits. Compared to standalone nonreciprocal devices, topologically-nontrivial electronic circuits provide an even larger toolbox to obtain various nonreciprocal functionalities by enforcing a wideband unidirectional transmission robust to defects and imperfections