gebhart/patrepeval huggingface dataset:
Multi-camera Multi-drone Detection, Tracking and Localization with Trajectory-based Re-identification (2021)

This paper presents a real-time multiple camera system for detecting, tracking and localizing multiple moving drones simultaneously in a 3 dimension space. The distinct feature of the system is in its target re-identification process, which provides for information fusion among cameras based on the targets' trajectories and relative locations. Drones are detected by the multiple camera system based on motion-based blob detection, and the 2D locations of each drone in individual camera frames are tracked by A geometry- and camera-based model. From the paths of the tracked drones, their trajectories are examined using drone track feature variable. Cross-correlated among cameras for object re-identifications will allow the individual 2D position information to be integrated into overall global 3D positions of all the tracked drones from all cameras. Preliminary outdoor flight demonstrations with 2 drones flying in formation and using 3 cameras show optimal results. The system is able to detect, track, localize and re-identifying individual drone with average positional error of 8%.
Electrochemical Approaches toward CO2 Capture and Concentration (2020)

Carbon capture and concentration of low partial pressure CO2 in air and flue gas is a key step in carbon abatement strategies. Traditional CO2 capture methods employ temperature or pressure swings; however, electrochemical swings, in which an applied potential modulates nucleophilicity, are also possible to mediate the capture and release of CO2. In contrast to the breadth of electrochemical CO2 reduction research, electrochemically mediated CO2 capture and concentration is an emerging field. Although some aspects are reminiscent of those in CO2 reduction, like local pH gradients and (bi)carbonate equilibria, ultimately electrochemical CO2 capture and concentration poses its own unique challenges that will benefit from insights from intercalative batteries, redox flow batteries, and biomimetic/-inspired design, among other fields. After an introduction to carbon capture and current chemical strategies, this Review highlights promising emerging electrochemical methods to enable CO2 capture and concentration; specifically discussed are organic redox, transition metal redox, and pH swings. It closes with an outlook and discussion of future research challenges for electrochemically mediated capture.
KLF4 c.A1322C Mutation Is a Consistent and Specific Genetic Feature of Raspberry-like Foveolar-type Adenoma of the Stomach (2022)

Naka, Tomoaki MD, PhD; Hashimoto, Taiki MD, PhD; Yoshida, Teruhiko MD, PhD; Yatabe, Yasushi MD, PhD; Sekine, Shigeki MD, PhD Author Information
Comparison of Target Antigens of Monoclonal Reagents OKT5, OKT8, and Leu2A, which Inhibit Effector Function of Human Cytotoxic T Lymphocytes (1983)

The OKT8 antigen, which is present on a subset of thymocytes and peripheral blood T lymphocytes, was examined utilizing a variety of biochemical techniques. It is shown to be a glycoprotein of 34 kD molecular weight which contains a hydrophobic region. Further, under nonreducing conditions, dimers of 76 kD and 67 kD are found. These species are most likely generated by differences in internal disulfide bonding. When two previously described antigens, OKT5 and Leu2A, were compared with OKT8, no structural differences could be found among the three antigens. Evidence is presented, however, which indicates that the three monoclonals recognize different epitopes on the molecule. Functional analysis on cytotoxic T lymphocyte (CTL) clones confirmed the biochemical findings concerning the identity of the three proteins.
Fiber-optic combined FPI/FBG sensors for monitoring of radiofrequency thermal ablation of liver tumors: ex vivo experiments (2014)

We present a biocompatible, all-glass, 0.2 mm diameter, fiber-optic probe that combines an extrinsic Fabry-Perot interferometry and a proximal fiber Bragg grating sensor; the probe enables dual pressure and temperature measurement on an active 4 mm length, with 40 Pa and 0.2°C nominal accuracy. The sensing system has been applied to monitor online the radiofrequency thermal ablation of tumors in liver tissue. Preliminary experiments have been performed in a reference chamber with uniform heating; further experiments have been carried out on ex vivo porcine liver, which allowed the measurement of a steep temperature gradient and monitoring of the local pressure increase during the ablation procedure.
High frequency extradural motor cortex stimulation transiently improves axial symptoms in a patient with Parkinson's disease (2008)

In a primate model of Parkinson's disease (PD), the benefit of extradural motor cortex stimulation (EMCS) was associated with high-frequency stimulation (130 Hz), whereas no significant motor improvement was achieved at 10 Hz or intermediate frequencies of stimulation. We report the case of a 72-year-old female patient affected by severe PD who underwent bilateral EMCS. In baseline med-off condition the patient was unable to arise from a chair and to stand without assistance. Stimulation at 3 and 60 Hz failed to provide any improvement of symptoms, whereas, when stimulating at 130 Hz, axial akinesia and walking improved consistently: the patient, in med-off condition, was able to arise from chair and to walk without assistance. The patient underwent two brain 99mTc- Ethylcysteinate Dimer-SPECT studies: semiquantitative and Statistical Parametric Mapping revealed that the regional cerebral perfusion was significantly increased in the supplementary motor area during stimulation at 130 Hz. After five months, the benefit of EMCS gradually disappeared.
Three‐dimensional MR angiography in imaging platinum alloy stents (2004)

The lumen of a platinum stent can be imaged with three-dimensional CE-MRA, although grading of restenosis has limited accuracy. The best results were obtained with a flip angle of 75 degrees and for stents in the iliac arteries parallel to B0.
Nonlinear mode coupling and resonant excitations in two-component Bose-Einstein condensates (2008)

Nonlinear excitations in two-component Bose-Einstein condensates (BECs) described by two coupled Gross-Pitaevskii equations are investigated analytically and numerically. The beating phenomenon, the higher-harmonic generation, and the mixing of the excited modes are revealed by both variational approximation and numerical method. The strong excitations induced by the parametric resonance are also studied by time-periodic modulation for the intercomponent interaction. The resonance conditions in terms of the modulation frequency and the strength of intercomponent interaction are obtained analytically, which are confirmed by numerical method. Direct numerical simulations show that, when the resonance takes place, periodic phase separation and multisoliton configurations (including soliton trains, soliton pairs, and multidomain walls) can be excited. In particular, we demonstrate a method for formation of multisoliton configurations through parametric resonance in two-component BECs.
Inside Front Cover: Cranberry Proanthocyanidin and Its Microbial Metabolite 3,4‐Dihydroxyphenylacetic Acid, but Not 3‐(4‐Hydroxyphenyl)‐Propionic Acid, Partially Reverse Pro‐Inflammatory microRNA Responses in Human Intestinal Epithelial Cells (2022)

Mol. Nutr. Food Res. 2022, 66, 202100853 DOI: 10.1002/mnfr.202100853 MicroRNAs (miRNA) are emerging as epigenetic modulators of intestinal response to nutrition. In article number 2100853, Elena M. Comelli and co-workers show that cranberry-derived proanthocyanidin (PAC) and its microbial metabolites affect the expression of intestinal miRNAs and are able to partially reverse an inflammatory insult to maintain intestinal homeostasis.
Fluorometric Determination of Total and Bound Sulfite in Wine by N-(9-Acridinyl)maleimide (1993)

N-(9-Acridinyl)maleimide (NAM) reacts with sulfite in wine and gives strong fluorescent derivatives that lead to highly sensitive fluorometry of both total and bound sulfite in wine. Values of free and bound sulfite in wine determined by the NAM method and the modified Rankine method agreed. Sulfite was determined in < 200 microL wine within 2 h.
Physical performance responses during 72 h of military operational stress (2002)

Decrements in performance during SUSOPS are primarily restricted to tasks that recruit muscles that are over-utilized without adequate recovery. General military skill tasks and occupational physical performance tasks are fairly well maintained.
Artificial mutations in P450c11AS (aldosterone synthase) can increase enzymatic activity: a model for low-renin hypertension? (1995)

The conversion of 11-deoxycorticosterone (DOC) to aldosterone is catalyzed by a single enzyme, termed P450c11AS, which has 11 beta-hydroxylase, 18-hydroxylase and 18-oxidase activities. The normotensive Dahl salt-resistant (R) rat has two mutation in P450c11AS that increase its aldosterone synthase activity. If such a mutation were to occur in human patients the predicted phenotype would be low-renin hypertension with elevated ratios of plasma aldosterone to plasma renin activity. Before searching for P450c11AS mutations in such patients we sought to determine if mutations in human P450c11AS could increase enzymatic activity in a fashion analogous to the Dahl R rat. We used site-directed mutagenesis of the human P450c11AS cDNA to create the mutants Glu 136-->Asp, Lys 251-->Arg and the combination of the two; these mutations correspond to those seen in the Dahl R rat. Cells transfected with these mutant human P450c11AS sequences could convert [14C]DOC to corticosterone, 18OH-corticosterone, and aldosterone. In particular the Lys 251-->Arg mutant produced 4 times as much 18OH-corticosterone and 50-80% more aldosterone than the wild type. These data show that mutations of human P450c11AS can increase enzymatic activity, suggesting that such mutations could, in theory, be the basis of some forms of human low-renin hypertension.
Hybrid and Cueing Receivers (2005)

The concept of the hybrid receiver can be used to design a receiver system to suit certain performance requirements. A number of possible combinations can be originated. As the electronic signal environment is getting more complicated, it might be difficult to process the signals in the environment with one kind of receiver. Some kind of hybrid combination might be a reasonable approach to solve the receiver problem.
Changes in Spatial Resolution at Position of the Detector in Digital Mammography System (2016)

엑스선유방촬영술은 다양한 유방질환 중 석회화 병변을 진단하는데 가장 효과적인 방법이다. 환자의 의료피폭 저감과 진단에 필요한 최적의 영상을 얻기 위해서는 성능유지를 지속적으로 관리해야 한다. 엑스선유방촬영술에서 엑스선을 발생시키는 양극의 경사각도는 중심선을 기준으로 하기 때문에 조사야 내의 위치에 따라 엑스선관의 유효초점이 미세하게 달라질 수 있어 공간분해능의 차이가 발생할 수 있다. 본 연구에서는 디지털 엑스선유방촬영장치에서 검출기 위치에 따른 LSF를 측정하여 MTF를 계산함으로써 공간분해능 변화에 대해서 연구하였다. 와이어 직경에 대한 변화에서 <TEX>$50{\mu}m$</TEX> 직경의 와이어의 경우 가장 높은 공간주파수 값을 나타냈으며 검출기의 픽셀보다 작은 직경을 갖는 와이어를 사용해야 검출기의 공간주파수에 따른 응답을 바르게 구할 수 있다는 것을 알 수 있었다. 조사야 내의 검출기의 위치에 따라서 공간주파수는 중심부분의 와이어가 나머지 와이어보다 우수한 MTF 특성을 보였으나, 그 차이는 미소하게 나타났다. 또한 중앙부분에서 반치폭 또는 유효초첨이 가장 작게 나타났으며 중앙에서 벗어날수록 반치폭이 증가하여 공간분해능이 낮아진 것으로 나타났다. X-ray mammography is the most effective method for the diagnosis of calcified lesions of various breast diseases. To reduce patient dose and to obtain optimal image required for diagnosis, the performance of the mammography system should be maintained continuously. Because the target (anode) angle of the X-ray tube is measured from the central X-ray, the effective angle can be slightly different in view of the position on the detector, which can result in degrading spatial resolution of the imaging within the field of view. In this study, we measured the MTF to examine spatial resolution for positions on the detector in the digital mammography system. For a tungsten wire of <TEX>$50{\mu}m$</TEX> diameter, the highest spatial frequency was obtained. It meant that a wire diameter for measuring MTF through LSF should be small compared to the pixel size of the detector used in the mammography system. The spatial resolution showed slightly different performance according to positions on the detector. The center position gave the best spatial resolution and positions away from the center showed the degraded performance although the difference of the spatial resolution was small. The effective focal spot size of the full width at half maximum also showed similar result. It concluded that the slightly increase of the effective focal spot size gave the degradation of the spatial resolution for positions on the detector.
High-Capacity, High-Rate Bi–Sb Alloy Anodes for Lithium-Ion and Sodium-Ion Batteries (2015)

Homogeneous alloys consisting of Bi and Sb have been fabricated by a facile high-energy mechanical milling with carbon and evaluated as potential anode materials in both lithium-ion and sodium-ion batteries. Specifically, Bi0.57Sb0.43-C and Bi0.36Sb0.64-C have been made, and they exhibit electrochemical performances superior to those of their counterparts Bi-C and Sb-C. For example, the Bi0.57Sb0.43-C sample delivers an initial delithiation capacity of 410 mA h g–1 and cycles stably for 300 cycles with a capacity decay of 0.09% per cycle at a current density of 200 mA g–1. It also exhibits high rate capacities in lithium-ion cells: 355 mA h g–1 at 5C current and 326 mA h g–1 at 7.8C current. In the case of a sodium-ion cell, its initial desodiation capacity is 375 mA h g–1 with a capacity retention of 78% at the 50th cycle. At a high current rate of 2.6C (1000 mA h g–1), it still delivers a desodiation capacity of 326 mA h g–1.
Coupling strategy between high-index and mid-index micro-metric waveguides for O-band applications (2022)

Abstract The integration of fast and power efficient electro-absorption modulators on silicon is of utmost importance for a wide range of applications. To date, Franz Keldysh modulators formed of bulk Ge or GeSi have been widely adopted due to the simplicity of integration required by the modulation scheme. Nevertheless, to obtain operation for a wider range of wavelengths (O to C band) a thick stack of Ge/GeSi layers forming quantum wells is required, leading to a dramatic increase in the complexity linked to sub-micron waveguide coupling. In this work, we present a proof-of-concept integration between micro-metric waveguides, through the butt-coupling of a 1.25 μm thick N-rich silicon nitride (SiN) waveguide with a 1.25 μm thick silicon waveguide for O-band operation. A numerical analysis is conducted for the design of the waveguide-to-waveguide interface, with the aim to minimize the power coupling loss and back-reflection levels. The theoretical results are compared to the measured data, demonstrating a coupling loss level of 0.5 dB for TE and TM polarisation. Based on the SiN-SOI interconnection, a theoretical analysis of a quantum-confined Stark effect (QCSE) stack waveguide coupled to an SiN waveguide is then proposed.
Encephaloceles of the Anterior Cranial Fossa (1995)

From a total of 114 encephaloceles treated surgically at The Hospital for Sick Children in the 15 years to 1994, the case records of 17 patients with sincipital and 5 patients with basal defects were reviewed retrospectively. The condition was evident at birth in 64% of patients, while the remainder presented with either cerebrospinal fluid (CSF) rhinorrhea, nasal obstruction, or feeding difficulty. Hypertelorism affected 73% of patients. All encephaloceles were repaired transcranially, at a mean age of 2 years, usually by means of an intradural pericranial graft. Five children with gross hypertelorism underwent orbital translocation at the time of encephalocele repair. Of those not corrected, primary and secondary hypertelorism regressed in most instances where the encephalocele was treated before the age of 2 years. There were no deaths. The only case of CSF rhinorrhea occurred in a patient with a basal defect, in whom intradural repair was not possible because of adherence of diencephalic structures to the sac wall. Hypertelorism recurred in 1 patient after orbital translocation, requiring recorrection 2 years later. One patient with untreated secondary hypertelorism failed to regress after the encephalocele was excised at the age of 4 months. Developmental outcome was normal in 59% of children, whilst 18% have mild mental or physical disability, and 23% are severely impaired. A child with a sincipital or basal defect and mild hypertelorism should have the encephalocele treated in early childhood to allow the facial skeleton to remodel with growth. When an encephalocele is accompanied by gross hypertelorism or a facial cleft, one-stage correction can be undertaken safely in early childhood with minimal mortality and acceptable morbidity.
Supercapacitors and interfacial charge accumulation devices (1992)

The energy consumption of electronic devices has decreased gradually with progress in integrated circuit technology. The stable working voltage required for power supplies is today considerably lower than in the first transistor devices. Furthermore, the development of amorphous silicon films makes possible a new design for many portable systems. The demand for miniaturized high energy density and low leakage current capacitors as, for example, a stand-by power source for RAM devices, for actuators or sensors as well the substitution of batteries by long-life power supplies offers new opportunities (pace-makers, watches where the supercapacitor is associated with a balance-wheel…) for capacitors using the electric double layer developed at a highly polarizable, blocking electrode/ electrolyte interface.
Analysis of p53 transactivation through high-affinity binding sites. (1993)

Alterations or elimination of the p53 protein is frequently occurring during human carcinogenesis. Overexpression of wild-type p53 has a profound growth-inhibitory effect on many cell lines, including strong and apparently non-sequence specific repression of a number of promoters. Consistent with the hypothesis that it acts as transcriptional regulator, wild-type p53 protein binds DNA and activates transcription of several promoters. We have studied DNA binding and transactivation (TA) properties of human wild-type and mutant p53 proteins representing four major mutational hotspots. DNA-gel retardation was used to detect specific p53-DNA complexes in nuclear extracts, with radiolabelled oligonucleotides representing high affinity p53-binding sites (HBS) as a probe. p53-specific complexes were identified by competition with unlabelled 'self' oligos and by double band-shifts in the presence of anti-p53 antibodies. To show transactivation by p53, TK promoter-driven CAT reporter gene was placed 3' of the p53-binding site. CAT activity was assayed after co-transfection of reporters with either wild-type (WT) or mutant p53 expression constructs into human cells that do not express p53 (SKOV3). We found that wild-type p53 has strong transactivating effect on the reporter. All mutants, with the exception of His273, were inactive in TA-assay. p53 is a target of several oncogenes found in DNA tumor viruses. We examined the effect of either SV40 T-ag or 55 kDa EIB protein of Ad5 on DNA binding and transactivation by p53 in transformed COS-1 and 293 cell lines, respectively. COS-1 extracts produced strong p53-dependent band-shift of the HBS oligos, that was doubleshifted by anti-p53 but not anti-T-ag antibodies, indicating that T-ag is not part of the complex. COS-1 cells had a high level of WT p53-dependent expression of transfected CAT reporter, indicating the presence of transactivation-competent p53, acting through the HBS element. In human Ad-transformed 293 cells, endogenous p53 was also transactivation competent and capable of DNA binding. In summary, we found efficient transactivation of HBS motif by WT and His273-p53. Studies of COS-1 and 293 cells suggest that a proportion of p53 in transformed cells display wild-type DNA binding and TA properties and that expression of transcriptionally inactive mutant p53 proteins in these cells does not interfere with WT-dependent transactivation.
Aging impairs smooth muscle-mediated regulation of aortic stiffness: a defect in shock absorption function? (2014)

Increased aortic stiffness is an early and independent biomarker of cardiovascular disease. Here we tested the hypothesis that vascular smooth muscle cells (VSMCs) contribute significantly to aortic stiffness and investigated the mechanisms involved. The relative contributions of VSMCs, focal adhesions (FAs), and matrix to stiffness in mouse aorta preparations at optimal length and with confirmed VSMC viability were separated by the use of small-molecule inhibitors and activators. Using biomechanical methods designed for minimal perturbation of cellular function, we directly quantified changes with aging in aortic material stiffness. An alpha adrenoceptor agonist, in the presence of N(G)-nitro-l-arginine methyl ester (l-NAME) to remove interference of endothelial nitric oxide, increases stiffness by 90-200% from baseline in both young and old mice. Interestingly, increases are robustly suppressed by the Src kinase inhibitor PP2 in young but not old mice. Phosphotyrosine screening revealed, with aging, a biochemical signature of markedly impaired agonist-induced FA remodeling previously associated with Src signaling. Protein expression measurement confirmed a decrease in Src expression with aging. Thus we report here an additive model for the in vitro biomechanical components of the mouse aortic wall in which 1) VSMCs are a surprisingly large component of aortic stiffness at physiological lengths and 2) regulation of the VSMC component through FA signaling and hence plasticity is impaired with aging, diminishing the aorta's normal shock absorption function in response to stressors.
A Concise Approach to the Synthesis of Carnosic Acid Type Diterpenes (2001)

10-vinyl-8,11,13-podocatriene 8, which is a modal of Carnosic acid type diterpenes, has been synthesized by an expeditious convergent synthetic approach.
Allograft Reconstruction After Resection of Malignant Tumors of the Scapula (2002)

The oncologic and functional outcomes of six patients who had scapular allograft reconstruction after scapulectomy for malignant tumors were reviewed. Five patients had Stage IIB and one patient had Stage IB tumors. Total scapulectomy was done in five patients, and partial scapulectomy (glenoid and neck) was done in one patient. Frozen glycerolized scapular allografts were implanted and fixed with plates and screws. The scapular muscles were reattached to the allograft. Tendon reconstruction to replace the excised muscles was done in two patients. The patients were followed up for an average of 3.8 years (range, 2-6 years). Cosmesis, elbow, and hand function were good in all patients. There were no infections, nonunions, or shoulder dislocations. One patient fractured the body of the allograft after a fall. One patient had local recurrence and had scapulectomy 5 years postoperatively. Two patients died 3 and 5 years postoperatively with lung metastases but with functioning grafts. The mean functional result using the Musculoskeletal Tumor Society functional score was 82 (range, 77-87). In this series, scapular allograft reconstruction restored cosmesis, shoulder stability, and function. Preservation or reconstruction of rotator cuff muscles is recommended.
Inhibition of cartilage proteoglycan release by a specific inactivator of cathepsin b and an inhibitor of matrix metalloproteinases. evidence for two converging pathways of chondrocyte‐mediated proteoglycan degradation (1993)

Cathepsin B is implicated in rHuIL-1 alpha-stimulated loss of cartilage proteoglycan. Its lack of involvement in retinoic acid-stimulated proteoglycan release suggests the existence of at least 2 pathways of cartilage proteoglycan breakdown, which may converge at the activation of a matrix prometalloproteinase.