gebhart/patrepeval huggingface dataset:
Fundamental Limits of HRR Profiling and Velocity Compensation for Stepped-Frequency Waveforms (2014)

A stepped-frequency (SF) waveform is effective in achieving high-range resolution (HRR) in modern radars. In this paper, we determine various fundamental limits of the SF waveform regarding the ambiguity, stability, and accuracy of stationary target profiling and the velocity compensation accuracy for moving targets. The investigation reveals that by using the information contained in both the phase and envelope of the echo signal, SF radars can achieve HRR profiles without ambiguity under a looser criterion and can compensate the range shift caused by a target's radial velocity. The results of this paper can aid in SF waveform design and in the development of processing algorithms for HRR profiling and velocity compensation.
Gastric stimulation for weight loss (2012)

The prevalence of obesity is growing to epidemic proportions, and there is clearly a need for minimally invasive therapies with few adverse effects that allow for sustained weight loss. Behavior and lifestyle therapy are safe treatments for obesity in the short term, but the durability of the weight loss is limited. Although promising obesity drugs are in development, the currently available drugs lack efficacy or have unacceptable side effects. Surgery leads to long-term weight loss, but it is associated with morbidity and mortality. Gastric electrical stimulation (GES) has received increasing attention as a potential tool for treating obesity and gastrointestinal dysmotility disorders. GES is a promising, minimally invasive, safe, and effective method for treating obesity. External gastric pacing is aimed at alteration of the motility of the gastrointestinal tract in a way that will alter absorption due to alteration of transit time. In addition, data from animal models and preliminary data from human trials suggest a role for the gut-brain axis in the mechanism of GES. This may involve alteration of secretion of hormones associated with hunger or satiety. Patient selection for gastric stimulation therapy seems to be an important determinant of the treatment's outcome. Here, we review the current status, potential mechanisms of action, and possible future applications of gastric stimulation for obesity.
Numerical Simulation for Three Dimensional Elastic-Plastic Contact with Hardening Behavior (2005)

An elastic-plastic contact (EPC) solution and code is developed using a modified semi-analytical method. The indentation tests with different hardening behavior are simulated by using the developed EPC code. The distributions of contact pressure, residual stress and plastic strain are obtained and compared with the results of the finite element method models without hardening. Some techniques, such as fast Fourier transform and fast convergence method, are used to increase the computation speed.
Activity, stereospecificity, and structure of Ziegler-Natta catalysts. (1987)

This paper summarizes some of our recent fundamental studies of isotactic polymerization of propylene. Based on the results of propylene polymerization with several kinds of one-component catalysts, the origin of polymerization activity is first discussed. The correlation between the oxidation states of titanium and polymerization activities for various olefins is clarified reasonably well from a detailed study of homo- and copolymerizations using a simplified catalyst. The role of MgCl2 on the enhancement of polymerization activity is also discussed in detail. The effect of internal and external donors in improving catalyst stereospecificity is then discussed; where are also presented the results of propylene polymerization using new types of highly active and isospecific catalysts originally found by Hercules Inc. and modified in our laboratory. A plausible model of isospecific catalytic center is finally proposed on the basis of these results.
A Combined Electrochemical‐Microfluidic Strategy for the Microscale‐Sized Selective Modification of Transparent Conductive Oxides (2017)

Abstract Surface chemical functionalization of transparent conductive oxides (TCOs) is helpful for a wide range of technological applications, ranging from solar cells to biomedical devices, as it allows to tune the electrical, optical, and morphological properties of TCOs toward the desired goal. The electrochemical grafting technique is a surface modification methodology affording robust coatings with tuneable properties and has the potential to be exploited for modifying TCO surfaces. However, due to technical limitations, like the use of a 3‐electrode cell and the need for low pH‐solutions, this approach has not been recurrently applied. Here a novel electrochemical‐microfluidic combined methodology is used where the use of a microchannel drives the spatially controlled covalent grafting of reagents on a TCO surface. To corroborate the validity of this approach in producing more complex chemical structures localized on selected microscale‐sized areas, where a first electrochemical grafting step takes place, an electrochemical glucose biosensor is realized through a layer‐by‐layer approach that shows a remarkable limit of detection in the micromolar concentration range. The sensing mechanism is based on an efficient electron transfer from glucose to the functionalized TCO surface. Biosensor performance is conveniently tuned by acting on the number of enzymatic units loaded onto the biosensor‐tree.
Discovery of a Novel RNA Suggests That Its Cellular Role Is More Complex than Just a Simple Messenger (2021)

A new research discovered that RNA could be glycosylated and displayed on the cell surface, suggesting the potential role of RNAs in inter-cellular communication.<br /><br />Yoon Jeong Park. Mol. Cells 2021;44:538-9. https://doi.org/10.14348/molcells.2021.0178
Micelle properties of a dimethylamino- and a trimethylammonium-tipped oxyethylene–oxybutylene diblock copolymer in water (2003)

Micelle properties in aqueous solution at temperatures in the range 20–50 °C of Me2N(CH2)2OE49B9 and I−Me3N+(CH2)2OE49B9, where E represents an oxyethylene unit and B an oxybutylene unit, have been investigated by dynamic and static light scattering, and the results compared with results for EmBn copolymers. For micelles of the dimethylamino-tipped copolymer in aqueous solution, the hydrodynamic radius, rh, was large relative to the thermodynamic radius, rt, suggesting a “soft” micelle. For the trimethylammonium-tipped copolymer, rh decreased and rt increased with increase in temperature, and values of association number, Nw, were low, but increased with increase in temperature, indicating a change from soft micelles at low temperature to small, less swollen micelles at high temperature. High values of thermodynamic volume per molecule, νt/Nw, for the polymer with the charged tip could be attributed to intramicellar charge effects. Addition of salt, to screen the charges, led to a decrease in νt/Nw and an increase in rh, rt and Nw.
Influence of multiplicative noise variance evaluation accuracy on mm-band SLAR image filtering efficiency (2004)

Image filtering is a stage commonly implied in remote sensing data processing in order to remove noise. In this paper we pay attention to filtering the images formed by millimeter (Ka) band side look aperture radars (SLARs) that can serve as imaging subsystems of multipurpose airborne remote sensing complexes. For SLAR images the dominant factor degrading their quality is multiplicative noise that is characterized by probability density function close to Gaussian and relative variance. The goal of this paper is to study how the errors in multiplicative noise variance evaluation influence the performance of different filters with application to Ka-band SLAR image processing. We have considered two test images, one containing a lot of texture and details, and the other image has many homogeneous regions. If the test image contains a lot of details and texture, the optimal value is commonly less than for test image that contains a large percentage of homogeneous regions. The error of variance evaluation more strongly influences the performance of the modified sigma filter than the performance of the local statistic Lee and DCT-based filters. The performance of filters greatly depends upon considered test image, noise statistical characteristics, setting the filter parameters. The numerical simulation data presented serve as good background and motivation for the design of locally adaptive filters that perform hard or soft switching of several different filter outputs in order to make use of the advantages of these filters and to avoid their drawbacks.
Ionization Potentials and Charge-Transfer Spectra of Substituted Benzenes (1955)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation L. E. Orgel; Ionization Potentials and Charge‐Transfer Spectra of Substituted Benzenes. J. Chem. Phys. 1 July 1955; 23 (7): 1352–1353. https://doi.org/10.1063/1.1742282 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioThe Journal of Chemical Physics Search Advanced Search |Citation Search
Infectious diseases. Call of the wild. (2009)

Zoonoses are infections acquired from animals. The most worrying are those that jump the species barrier and then pass from human to human, such as swine flu. The human animal infections and risk surveillance group was set up in 2004 to improve the process of spotting infections, assessing risk and responding. The Health Protection Agency is working with veterinary colleges to prepare for newer and unrecognised infections.
Adsorbents for Green Transporation. (2013)

For the past few decades, research has gone towards devising more efficient and lower pollution transportation. This seminar covers the shift in focus from a hydrogen economy towards carbon reduction and the similar challenges that both pose for adsorption. The mechanism for hydrogen spillover is analyzed and presented, with an emphasis on the practicality of the technology and newly defined maximum storage capacity. In contrast, carbon dioxide capture from the atmosphere is analyzed and presented for zeolite type X, designed to produce >90% purity CO2 during a single cycle, using a two bed system in tandem. Additionally, new amine based adsorbents will be presented as an option to optimize binding energies of carbon dioxide while keeping the high selectivity of traditional amine adsorbents. The culmination of the research is in new adsorbents that incorporate metal nanoparticles to act as gates, selectively allowing some gases into the adsorbent, while rejecting others. Hopefully this can lead to new designs in separations that fully integrate both membranes and adsorbents into one process.
Pregnancy, Primary Aldosteronism and Somatic CTNNB1 Mutations in the Adrenal (2015)

Recent discoveries of somatic mutations permit the recognition of sub-types of aldosterone-producing adenomas (APA) with different clinical presentations and pathology. Here we describe two women who presented in pregnancy, and one woman who presented post-menopause, with hyperaldosteronism. Their APAs harbored activating mutations of CTNNB1, encoding β-catenin in the Wnt cell-differentiation pathway, and expressed >100-fold higher levels of LHCGR and GNRHR, encoding gonadal receptors, than other APAs. The mutations stimulate Wnt activation and cause adrenocortical cells to de-differentiate towards their common gonad-adrenal precursor cell-type.
Negative correlation between plasma fibrinogen and insulin sensitivity measured with the minimal model technique. (1998)

We aimed at investigating relationship between plasma fibrinogen and insulin sensitivity, which are two major determinants of metabolic Syndrome X (insulin resistance syndrome). We designed a prospective study of 27 non-diabetic, non-hypertensive subjects, presenting a wide range of body mass index BMI (10 men, 17 women; mean age+/-SEM: 35.9+/-2.2 years; BMI ranging from 21.1-45.2 kg/m2). Insulin sensitivity was assessed with the minimal model procedure, over a 180 min intravenous glucose tolerance test with iterative sampling. Fibrinogen levels were determined by the method of Clauss. The insulin sensitivity index SI (i.e., the slope of the dose-response relationship between insulin increased above baseline and glucose disposal) ranged from 0.0009 to 16 x 10(-4) min(-1)/(microU/ml), with a mean value of 4.76+/-0.73 x 10(-4). Mean values of plasma fibrinogen were 3.33+/-0.13 g/l, ranging from 2.21 to 5.07 g/l. There were highly significant negative correlations between SI and the level of plasma fibrinogen (r = -0.61, p = 0.0007) and between the basal effect of insulin BIE and plasma fibrinogen (r = -0.521, p = 0.005). Basal insulin was positively correlated to fibrinogen (r = 0.386, p = 0.046). When we analysed the data using partial correlation analysis, the negative relation between SI and fibrinogen was maintained independently from BMI (r = -0.45, p < 0.05). These data establish a strong negative association between insulin sensitivity and fibrinogen, involved in the increased cardiovascular risk of metabolic Syndrome X.
Preparation and characterization of hollow carbon nanospheres (2015)

Graphene particles in the form of hollow carbon nanospheres ranging in wall thickness from ≃1 to 12 nm have been produced via methane pyrolysis at temperatures from 500 to 900°C on spherical SiO2 nanoparticles 40 to 80 nm in average diameter, followed by dissolution of the template. We have prepared aqueous dispersions of the nanospheres with the Triton X-100 surfactant and demonstrated the possibility of producing electrodes from the nanospheres. The electrodes have been preliminarily tested for electrosorption from NaCl solutions.
Determination of Zinc by Direct Extraction from Urine with Diphenylthiocarbazone (1958)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDetermination of Zinc by Direct Extraction from Urine with DiphenylthiocarbazoneJ. H. R. Kagi and B. L. ValleeCite this: Anal. Chem. 1958, 30, 12, 1951–1954Publication Date (Print):December 1, 1958Publication History Published online1 May 2002Published inissue 1 December 1958https://doi.org/10.1021/ac60144a020RIGHTS & PERMISSIONSArticle Views114Altmetric-Citations27LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (537 KB) Get e-Alerts Get e-Alerts
High-Potency Sweeteners Derived from β-Amino Acids (1991)

Over the last 20-25 years, intense effort has been focused on the discovery of novel sweeteners. Suosan, N-(4-nitrophenyl)-N'-(2-carboxyethyl)urea is a known synthetic sweetener which contains an aryl substituent and an acidic moiety. Aspartyl amide sweeteners contain a hydrophobic component and an acidic moiety. We designed analogues in which a hydrophobic unit was incorporated in suosan type sweeteners providing increased potency.
Evaluation of Time-Sensitive Information Multicasting Using Tree-Structured Overlay Network (2011)

The multicasting of information is needed in a variety of situations. For example, when a local government has the necessity to distribute emergency information of natural disaster to the public or when a shop advertises goods for a time-limited sale. This information is generally time-sensitive and needs to deliver quickly. We have studied multicasting of such time-sensitive information using a tree-structured overlay network, and have shown that the overlay network allows information to be delivered quickly. In this paper, we show the validity of tree-structured overlay network through conducting several experiments under real conditions, and analyze the advantages of P2P architecture in more general situation.
On the Queue Number of Planar Graphs (2010)

We prove that planar graphs have poly-logarithmic queue number, thus improving upon the previous polynomial upper bound. Consequently, planar graphs admit 3D straight-line crossing-free grid drawings in small volume.
Comparison of Methods for the Propagation of Component Modeling Uncertainty. (2007)

Abstract not provided.
Chip integration using inkjet-printed silver conductive tracks reinforced by electroless plating for flexible board packages (2012)

NA is a significant problem, difficult to assess, and can lead to dnDSA development also in our population. Identifying risk factors for NA might be an underestimated tool to improve graft and patient outcome in KTRs.
Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds (2023)

Described herein are bacteriochlorins comprising an annulated isocyclic ring such as a compound Formula I: or a metal conjugate thereof, wherein: R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, and Z are each as defined herein. Also described are methods and intermediates for the synthesis of bacteriochlorins comprising an annulated isocyclic ring, and methods of using such bacteriochlorins for, among other things, diagnostic and therapeutic purposes such as, e.g., luminescent compounds in flow cytometry, and/or as active agents in photodynamic therapy (PDT).
Structure–function–folding relationship in a WW domain (2006)

Protein folding barriers result from a combination of factors including unavoidable energetic frustration from nonnative interactions, natural variation and selection of the amino acid sequence for function, and/or selection pressure against aggregation. The rate-limiting step for human Pin1 WW domain folding is the formation of the loop 1 substructure. The native conformation of this six-residue loop positions side chains that are important for mediating protein-protein interactions through the binding of Pro-rich sequences. Replacement of the wild-type loop 1 primary structure by shorter sequences with a high propensity to fold into a type-I' beta-turn conformation or the statistically preferred type-I G1 bulge conformation accelerates WW domain folding by almost an order of magnitude and increases thermodynamic stability. However, loop engineering to optimize folding energetics has a significant downside: it effectively eliminates WW domain function according to ligand-binding studies. The energetic contribution of loop 1 to ligand binding appears to have evolved at the expense of fast folding and additional protein stability. Thus, the two-state barrier exhibited by the wild-type human Pin1 WW domain principally results from functional requirements, rather than from physical constraints inherent to even the most efficient loop formation process.
Spiny mice activate unique transcriptional programs after severe kidney injury regenerating organ function without fibrosis (2021)

Fibrosis-driven solid organ failure is an enormous burden on global health. Spiny mice (<i>Acomys</i>) are terrestrial mammals that can regenerate severe skin wounds without scars to avoid predation. Whether spiny mice also regenerate internal organ injuries is unknown. Here, we show that despite equivalent acute obstructive or ischemic kidney injury, spiny mice fully regenerate nephron structure and organ function without fibrosis, whereas C57Bl/6 or CD1 mice progress to complete organ failure with extensive renal fibrosis. Two mechanisms for vertebrate regeneration have been proposed that emphasize either extrinsic (pro-regenerative macrophages) or intrinsic (surviving cells of the organ itself) controls. Comparative transcriptome analysis revealed that the <i>Acomys</i> genome appears poised at the time of injury to initiate regeneration by surviving kidney cells, whereas macrophage accumulation was not detected until about day 7. Thus, we provide evidence for rapid activation of a gene expression signature for regenerative wound healing in the spiny mouse kidney.
A 0.13 μm CMOS System-on-Chip for a 512 × 424 Time-of-Flight Image Sensor With Multi-Frequency Photo-Demodulation up to 130 MHz and 2 GS/s ADC (2014)

We introduce a 512 × 424 time-of-flight (TOF) depth image sensor designed in a TSMC 0.13 μm LP 1P5M CMOS process, suitable for use in Microsoft Kinect for XBOX ONE. The 10 μm × 10 μm pixel incorporates a TOF detector that operates using the quantum efficiency modulation (QEM) technique at high modulation frequencies of up to 130 MHz, achieves a modulation contrast of 67% at 50 MHz and a responsivity of 0.14 A/W at 860 nm. The TOF sensor includes a 2 GS/s 10 bit signal path, which is used for the high ADC bandwidth requirements of the system that requires many ADC conversions per frame. The chip also comprises a clock generation circuit featuring a programmable phase and frequency clock generator with 312.5-ps phase step resolution derived from a 1.6 GHz oscillator. An integrated shutter engine and a programmable digital micro-sequencer allows an extremely flexible multi-gain/multi-shutter and multi-frequency/multi-phase operation. All chip data is transferred using two 4-lane MIPI D-PHY interfaces with a total of 8 Gb/s input/output bandwidth. The reported experimental results demonstrate a wide depth range of operation (0.8–4.2 m), small accuracy error ( <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">$&lt;$</tex></formula> 1%), very low depth uncertainty ( <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">$&lt;$</tex></formula> 0.5% of actual distance), and very high dynamic range ( <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">$&gt;$</tex></formula> 64 dB).
Two-dimensional colloidal crystal heterostructures (2015)

A simple method to fabricate colloidal crystal heterostructures based on a two-dimensional colloidal crystal was developed.