gebhart/patrepeval huggingface dataset:
THE PHYSICAL, MENTAL AND SOCIAL IMPACTS OF TELLING PROSTATE CANCER PATIENTS THE TRUE DIAGNOSIS (1997)

These results suggest that the mental condition of prostate cancer patients remain stable when they are in good physical condition regardless of being informed the true diagnosis or not. However, the patients who weren't told the true diagnosis have a tendency to get depression accompanying deterioration of physical condition. It is therefore considered that telling the true diagnosis makes the patients understand the changes of their physical conditions and help their mind to be stable.
UntrimmedNets for Weakly Supervised Action Recognition and Detection (2017)

Current action recognition methods heavily rely on trimmed videos for model training. However, it is expensive and time-consuming to acquire a large-scale trimmed video dataset. This paper presents a new weakly supervised architecture, called UntrimmedNet, which is able to directly learn action recognition models from untrimmed videos without the requirement of temporal annotations of action instances. Our UntrimmedNet couples two important components, the classification module and the selection module, to learn the action models and reason about the temporal duration of action instances, respectively. These two components are implemented with feed-forward networks, and UntrimmedNet is therefore an end-to-end trainable architecture. We exploit the learned models for action recognition (WSR) and detection (WSD) on the untrimmed video datasets of THUMOS14 and ActivityNet. Although our UntrimmedNet only employs weak supervision, our method achieves performance superior or comparable to that of those strongly supervised approaches on these two datasets.
[Radioresistant subline of human glioma cell line MGR2R induced by repeated high dose X-ray irradiation]. (2006)

After intermittent high dose X-ray irradiation, radiosensitive cell line MGR2 has been induced to be relatively radioresistant (MGR2R). MGR2R cells grow slower and have G(1) phase and G(2) phase arrest which might relate to its radioresistance.
Direct Parameter Extraction Of Base and Emitter Resistances For SiGe HBTs Using DC Data Only (2010)

A new method to directly extract base and emitter resistance parameters for SiGe HBTs using the Mextram bipolar compact transistor model has been presented. The method only requires a standard forward Gummel measurement and accounts for several second order effects like high-injection base conductivity modulation, Early effect and emitter current crowding. Base and emitter resistance parameters have been extracted over a wide temperature range (300K - 93K) for a first generation 0.5µm SiGe HBT with a peak cut-off frequency of 50 GHz at 300K. The HBT features a heavily doped poly-silicon emitter, an extrinsic base region doped well above the Mott's transition (3e18 cc for boron in silicon) and an intrinsic base region doped very close to the Mott's transition. The extracted parameters have been verified by comparison with several different methods.
Elucidating the Mechanism of Reversible Oxiranations via Magnetization Transfer Spectroscopy (2012)

The reversible [2 + 1] cycloadditions between an N,N'-diamidocarbene (DAC) and eight aldehydes were examined using NMR spectroscopy. Variable temperature magnetization transfer experiments revealed higher exchange rates and lower activation barriers when electron-deficient aldehydes were employed. Likewise, competitive equilibrium studies indicated a thermodynamic preference for electron-deficient aryl and sterically unhindered alkyl aldehydes compared to more electron-rich or bulkier substrates. Collectively, these and other data collected were consistent with the oxiranation process proceeding in an asynchronous manner.
Optical modulator with independent control of attenuation and spectral tilt (2002)

We describe here a device based on the mechanical anti-reflection switch, or MARS modulator for use in WDM networks. The MARS modulator is a broad spectrum, high contrast reflection modulator based on the vertical movement of an optical membrane above a substrate. The movement is via electric force on the membrane induced by a bias applied between the membrane and the substrate.
Transmembrane Amyloid-Related Proteins in CSF as Potential Biomarkers for Alzheimerâ€™s Disease (2015)

In the continuing search for new cerebrospinal fluid (CSF) biomarkers for Alzheimer's disease (AD), reasonable candidates are the secretase enzymes involved in the processing of the amyloid precursor protein (APP), as well as the large proteolytic cleavage fragments sAPPα and sAPPβ. The enzymatic activities of some of these secretases, such as BACE1 and TACE, have been investigated as potential AD biomarkers, and it has been assumed that these activities present in human CSF result from the soluble truncated forms of the membrane-bound enzymes. However, we and others recently identified soluble forms of BACE1 and APP in CSF containing the intracellular domains, as well as the multi-pass transmembrane presenilin-1 (PS1) and other subunits of γ-secretase. We also review recent findings that suggest that most of these soluble transmembrane proteins could display self-association properties based on hydrophobic and/or ionic interactions leading to the formation of heteromeric complexes. The oligomerization state of these potential new biomarkers needs to be taken into consideration for assessing their real potential as CSF biomarkers for AD by adequate molecular tools.
Induction of Protective Cellular Immunity againstMycobacterium tuberculosisby Recombinant Attenuated Self-DestructingListeria monocytogenesStrains Harboring Eukaryotic Expression Plasmids for Antigen 85 Complex and MPB/MPT51 (2004)

We report here the induction of specific protective cellular immunity against Mycobacterium tuberculosis by the employment of vaccination with recombinant attenuated Listeria monocytogenes strains. We constructed self-destructing attenuated L. monocytogenes Delta 2 strains carrying eukaryotic expression plasmids for the antigen 85 complex (Ag85A and Ag85B) and for MPB/MPT51 (mycobacterial protein secreted by M. bovis BCG/mycobacterial protein secreted by M. tuberculosis) molecules. Infection of these recombinant bacteria allowed expression of the genes in the J774A.1 murine macrophage cell line. Intraperitoneal vaccination of C57BL/6 mice with these recombinant bacteria was capable of inducing purified protein derivative-specific cellular immune responses, such as foot pad reactions, proliferative responses of splenocytes, and gamma interferon production from splenocytes, suggesting the efficacy of vaccination against mycobacterial infection by use of these recombinant L. monocytogenes strains. Furthermore, intravenous vaccination with recombinant bacteria carrying expression plasmids for Ag85A, Ag85B, or MPB/MPT51 in BALB/c mice elicited significant protective responses, comparable to those evoked by a live Mycobacterium bovis BCG vaccine. Notably, this is the first report to show that MPB/MPT51 is a major protective antigen in addition to Ag85A and Ag85B, which have been reported to be major mycobacterial protective antigens.
Increasing Output Compaction in Presence of Unknowns Using an X-Canceling MISR with Deterministic Observation (2008)

Recently, an X-canceling MISR methodology was proposed in Touba (2007) which was based on providing very high probabilistic error coverage by canceling out X's in MISR signatures. This paper investigates a new methodology for using the X-canceling MISR architecture based on deterministically observing scan cells. The two main advantages of the proposed approach are (1) it can provide a higher amount of compaction, and (2) it is effective for larger percentages of X's in the output response. Also, this paper investigates a hybrid approach that combines X-masking with an X-canceling MISR. Experimental results indicate that significant amounts of output compression can be achieved with no loss of fault coverage.
Tuberculosis in swine (2017)

Tuberculosis is of frequent occurrence in hogs, and, apparently, the number of hogs so affected is on the increase. So true is this in some sections of the country that packers are cautious about buying hogs from those localities. The carcasses of tuberculous animals are often so thoroughly infected with the disease as to be unfit for food, and consequently are a source of loss to the packer. Where animals are slaughtered without being subjected to careful inspection, the diseased meat is very certain to be unwittingly used for food. A knowledge of the sources of infection and of the extent to which the disease is readily spread is of primary inportance to those who must undertake the responsibility of checking it.
Ageing quantification of supercapacitors during calendar life and power cycling tests (2009)

International audience
Front Cover: Investigation of the Reaction Pathways of Biomass‐Derived Oxygenate Conversion into Monoalcohols in Supercritical Methanol with CuMgAl‐Mixed‐Metal Oxide (ChemSusChem 23/2018) (2018)

The Front Cover shows the chemical intermediates and final products for the catalytic conversion of wood into C2–C6 alcohols over a CuMgAl oxide catalyst in methanol. In their Full Paper, P. H. Galebach et al. elucidate the pathway and measure the reaction rate of the key reactions that produce the alcohols. The solubilized wood components are converted into diols in methanol. C−C scission between vicinal diols produces the alcohols which do not further react. Larger diols are produced by C−C methylation coupling reactions between methanol and diols. The rate of the C−C coupling reactions is greater than the rate of C−C scission reactions. Hydrogen for this process is produced from reforming of the methanol. More information can be found in the Full Paper by P. H. Galebach et al. on page 4007 in Issue 23, 2018 (DOI: 10.1002/cssc.201801816).
Compressed Wannier modes found from an $L_1$ regularized energy functional (2014)

We propose a method for calculating Wannier functions of periodic solids directly from a modified variational principle for the energy, subject to the requirement that the Wannier functions are orthogonal to all their translations ("shift-orthogonality"). Localization is achieved by adding an $L_1$ regularization term to the energy functional. This approach results in "compressed" Wannier modes with compact support, where one parameter $μ$ controls the trade-off between the accuracy of the total energy and the size of the support of the Wannier modes. Efficient algorithms for shift-orthogonalization and solution of the variational minimization problem are demonstrated.
Regulation of C2C12 myogenic terminal differentiation by MKK3/p38α pathway (2003)

The signal transduction pathways connecting cell surface receptors to the activation of muscle-specific promoters and leading to myogenesis are still largely unknown. Recently, a contribution of the p38 mitogen-activated protein kinase (MAPK) pathway to this process was evoked through the use of pharmacological inhibitors. We used several mutants of the kinases composing this pathway to modulate the activity of the muscle-specific myosin light chain and myogenin promoters in C2C12 cells by transient transfections. In addition, we show for the first time, using a stable C2C12 cell line expressing a dominant-negative form of the p38 activator MAPK kinase (MKK)3, that a functional p38 MAPK pathway is indeed required for terminal muscle cell differentiation. The most obvious phenotype of this cell line, besides the inhibition of the activation of p38, is its inability to undergo terminal differentiation. This phenotype is accompanied by a drastic inhibition of cell cycle and myogenesis markers such as p21, p27, MyoD, and troponin T, as well as a profound disorganization of the cytoskeleton.
On the extraordinary spectral similarity of nickel(II) phthalocyanine and bis(.beta.-diiminotetracyanopyrrolizinato)nickel(II) (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOn the extraordinary spectral similarity of nickel(II) phthalocyanine and bis(.beta.-diiminotetracyanopyrrolizinato)nickel(II)Shinichiro Nakamura, Alberto Flamini, Vincenzo Fares, and Masafumi AdachiCite this: J. Phys. Chem. 1992, 96, 21, 8351–8356Publication Date (Print):October 1, 1992Publication History Published online1 May 2002Published inissue 1 October 1992https://pubs.acs.org/doi/10.1021/j100200a026https://doi.org/10.1021/j100200a026research-articleACS PublicationsRequest reuse permissionsArticle Views77Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Lattice Vibration Spectra of Aluminum Nitride (1967)

The reflectivity and transmission spectra of aluminum nitride have been measured using unpolarized radiation in the wavelength region 2 to 30 \ensuremath{\mu}. The dielectric parameters and the zone-center ($k\ensuremath{\simeq}0$) opticalmode energies [transverse (TO) and longitudinal (LO)] have been calculated from the reflectivity measurements using dispersion theory. The values obtained are TO=82.7 meV (666.7 ${\mathrm{cm}}^{\ensuremath{-}1}$), LO=113.6 meV (916.3 ${\mathrm{cm}}^{\ensuremath{-}1}$), ${\ensuremath{\epsilon}}_{\ensuremath{\infty}}=4.84$, and ${\ensuremath{\epsilon}}_{0}=9.14$. From these data the value calculated for the Szigeti effective charge is ${q}^{*}=1.2$. Polarization measurements have revealed a sharp minimum in the reststrahlen band for $E$ parallel to the $c$ axis at \ensuremath{\sim}111.0 meV. Otherwise the reflectivity curves appear identical for both polarizations. Thirteen absorption bands have been observed on the high-energy side of the reflectivity band. A tentative interpretation is proposed in which these bands are considered to be due to combinations of six representative phonon branches at or near the Brillouin-zone boundary ($\mathbf{k}\ensuremath{\simeq}{\mathbf{k}}_{max}$). The phonon energies resulting from this interpretation are LO=91.4, T${\mathrm{O}}_{1}$=82.5, T${\mathrm{O}}_{2}$=78.1, LA=62.9, T${\mathrm{A}}_{1}$=55.3, and T${\mathrm{A}}_{2}$=50.9 meV.
Multigene Phylogeny of Epichloe Species, Fungal Symbionts of Grasses (2001)

K. D. Craven, P. T. W. Hsiau, A. Leuchtmann, W. Hollin, C. L. Schardl, Multigene Phylogeny of Epichloe Species, Fungal Symbionts of Grasses, Annals of the Missouri Botanical Garden, Vol. 88, No. 1 (Winter, 2001), pp. 14-34
Securing data and financial transactions (2002)

The primary origin of the data transaction security problem is the remote nature of the transaction. The same technology that has aided in simplifying and promoting electronic commerce has made it more difficult to know who is actually initiating the transaction. Frequently, the individual is at the remote end of a communication channel and identifiable only by something they possess, such as a card, or something they know, such as a password, personal identification number (PIN) or encryption key. This paper describes ways to use biometric techniques to secure electronic transactions.
Molecular and Functional Analyses of Amino Acid Decarboxylases Involved in Cuticle Tanning in Tribolium castaneum (2009)

Aspartate 1-decarboxylase (ADC) and 3,4-dihydroxyphenylalanine decarboxylase (DDC) provide beta-alanine and dopamine used in insect cuticle tanning. beta-Alanine is conjugated with dopamine to yield N-beta-alanyldopamine (NBAD), a substrate for the phenol oxidase laccase that catalyzes the synthesis of cuticle protein cross-linking agents and pigment precursors. We identified ADC and DDC genes in the red flour beetle, Tribolium castaneum (Tc), and investigated their functions. TcADC mRNA was most abundant prior to the pupal-adult molt. Injection of TcADC double-stranded (ds) RNA (dsTcADC) into mature larvae resulted in depletion of NBAD in pharate adults, accumulation of dopamine, and abnormally dark pigmentation of the adult cuticle. Injection of beta-alanine, the expected product of ADC, into dsTcADC-treated pupae rescued the pigmentation phenotype, resulting in normal rust-red color. A similar pattern of catechol content consisting of elevated dopamine and depressed NBAD was observed in the genetic black mutants of Tribolium, in which levels of TcADC mRNA were drastically reduced. Furthermore, from the Tribolium black mutant and dsTcADC-injected insects both exhibited similar changes in material properties. Dynamic mechanical analysis of elytral cuticle from beetles with depleted TcADC transcripts revealed diminished cross-linking of cuticular components, further confirming the important role of oxidation products of NBAD as cross-linking agents during cuticle tanning. Injection of dsTcDDC into larvae produced a lethal pupal phenotype, and the resulting grayish pupal cuticle exhibited many small patches of black pigmentation. When dsTcDDC was injected into young pupae, the resulting adults had abnormally dark brown body color, but there was little mortality. Injection of dsTcDDC resulted in more than a 5-fold increase in levels of DOPA, indicating that lack of TcDDC led to accumulation of its substrate, DOPA.
Blastic plasmacytoid dendritic cell neoplasm in children: diagnostic features and clinical implications (2010)

In contrast to adult cases, in which long-term survival depends on stem cell transplantation in first complete remission, blastic plasmacytoid dendritic cell neoplasms in children are clinically less aggressive. Treatment with high-risk acute lymphoblastic leukemia-type chemotherapy appears to be effective, and stem cell transplantation may be reserved for children who relapse and achieve a second remission. Outcomes were more favorable in cases that lacked cutaneous disease at presentation, although a comparison of cutaneous and non-cutaneous cases might be confounded by differences in treatment regimens. Focal expression of S-100 may be seen in concert with other markers of plasmacytoid dendritic cells.
Underwater Network Management System in Internet of Underwater Things: Open Challenges, Benefits, and Feasible Solution (2020)

As oceans cover the majority of the earth’s surface, it becomes inevitable in extending the concepts of Internet of Things (IoT) to ocean bodies, thereby tiling the way for a new drift in the digital world, the Internet of Underwater Things (IoUT). The primary objective of IoUT is the creation of a network of several smart interconnected undersea things, to digitally link water bodies by using devices such as autonomous underwater vehicles. Since the traditional ideas of IoT cannot be merely expanded to underwater, due to the difference in environmental characteristics, this puts forward a variety of challenges for scientists to work with IoUT, and one such challenge is the network management with IoUT. This paper gives an overview on (1) underwater network management systems (U-NMS) using acoustic communication in IoUT; (2) the challenges and benefits and use cases of U-NMS; (3) fault, configuration, accounting, performance, security and constrained management (FCAPSC) functionalities of U-NMS and (4) a comparison between network management system in IoT and U-NMS system in IoUT. Additionally, this paper shows the prototype design and implementation setup of U-NMS in a laboratory environment, using lightweight machine to machine (LWM2M) and acoustic communication technology for IoUT. This paper will contribute much to the profit of researchers and industry players in uncovering the critical areas of the Internet of Underwater Things.
Biopsy and histopathologic diagnosis of oral premalignant and malignant lesions. (2008)

Accurate diagnosis of premalignant or malignant oral lesions depends on the quality of the biopsy, adequate clinical information and correct interpretation of the biopsy results. The purpose of this paper is to review the procedures for obtaining appropriate biopsy samples, and the criteria for diagnosing and grading dysplasias. The World Health Organization's description of the architectural and cytologic epithelial changes that characterize dysplasia is detailed, and guidelines for following up patients with premalignant and malignant lesions are provided. The benefits of using the centralized services and expertise of the British Columbia Oral Biopsy Service are also reviewed.
Epilepsy: A classification for all seasons? (2012)

Epilepsy classification is close to the heart of every clinician because it affects every consultation. Acceptance of change to fundamental concepts is difficult and implementation of new ideas requires considerable effort. It is therefore not surprising that the 2010 Organization of the epilepsies has evoked much passion and its fair share of criticism and controversy. Debate has been positive and has already led to modifications and gradual acceptance of the new framework. Although classification will never be perfect and continues to evolve with increasing knowledge, the time for updating our thinking to reflect current concepts and scientific understanding is well and truly here. Ongoing discussion will help to further mature the new organization.
Changes in the echoes from ultrasonic contrast agents with imaging parameters (1998)

Current harmonic imaging scanners transmit a narrowband signal that limits spatial resolution in order to differentiate the echoes from tissue from the echoes from microbubbles. Because spatial resolution is particularly important in applications, including mapping vessel density in tumors, we explore the use of wideband signals in contrast imaging. It is first demonstrated that microspheres can be destroyed using one or two pulses of ultrasound. Thus, temporal signal processing strategies that use the change in the echo over time can be used to differentiate echoes from bubbles and echoes from tissue. Echo parameters, including intensity and spectral shape for narrowband and wideband transmission, are then evaluated. Through these experiments, the echo intensity received from bubbles after wideband transmission is shown to be at least as large as that for narrowband transmission, and can be larger. In each case, the echo intensity increases in a nonlinear fashion in comparison with the transmitted signal intensity. Although the echo intensity at harmonic multiples of the transmitted wave center frequency can be larger for narrowband insonation, echoes received after wideband insonation demonstrate a broadband spectrum with significant amplitude over a very wide range of frequencies.