gebhart/patrepeval huggingface dataset:
Hybrid Electronic/Non Coherent Optical Processor For Large Scale Phased Arrays (1989)

An hybrid electronic/optical processor for large scale phased arrays is described . The optical stage , based on a non coherent lensless shadow-casting architecture , is detailed . This system is applied to RIAS air coverage radar data processing (RIAS = Synthetic Aperture Pulse Radar), and experimental results are provided .
New tandem radical cyclizations directed toward the synthesis of crinipellin A (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew tandem radical cyclizations directed toward the synthesis of crinipellin AC. Eric Schwartz and Dennis P. CurranCite this: J. Am. Chem. Soc. 1990, 112, 25, 9272–9284Publication Date (Print):December 1, 1990Publication History Published online1 May 2002Published inissue 1 December 1990https://pubs.acs.org/doi/10.1021/ja00181a033https://doi.org/10.1021/ja00181a033research-articleACS PublicationsRequest reuse permissionsArticle Views1943Altmetric-Citations109LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A Model for Toughening of Semicrystalline Polymers (2007)

Dispersing particles within a semicrystalline polymer can result in remarkable impact strength improvement and opens promising routes toward super-tough materials. Although the technique is extensively employed to modify polymer properties, predicting which dispersions yield toughness remains a challenging issue. By comparing the characteristic lengths and deformation processes involved in toughening, we explain why a minimum matrix confinement or ligament thickness is required to induce ductility. Our model was used to interpret experimental data and show how this critical confinement length depends on material properties, temperature, and processing history. Most importantly, it reveals an unexpected particle size effect. The predictions provide fresh insight into the design of toughened materials. The model also provides guidance to understanding the fracture mechanics of other complex systems such as composites or biological matter.
Electronic Pillbox Logger for people with Parkinson's Disease (2000)

Parkinson' Disease (PD) is a motor disorder characterized by rigidity, tremor, and hypokinesia with secondary manifestations like defective posture and gait, mask like face and dementia. Over the years it may lead to inability to move, breath and ultimately patient may succumb to chest infection and embolism. Prevalence studies show that more than six million people around the world suffer from PD. At present, there is no cure for PD but there are effective treatments that can slow the progression of the disease and regulate its affects. PD results from a deficiency of dopamine so most drugs that produce a salutary effect in PD either potentiate dopamine or work as dopamine agonists. Hence, to keep the symptoms of PD to a minimum it is very important that the medications be consumed regularly, so that the dopamine level is maintained in the body of the subject. Electronic pillbox logger is a device that has been designed to ensure this very much required medication adherence in PD subjects, which can also be used to measure the response to oral medication. This work describes the design and implementation of an electronic pillbox logger for use by people suffering from Parkinson's disease (PD). The pillbox logger is designed to track medication adherence and prompt the user to take medication on time. It is pocket-sized, portable, and compartmented. It has a variety of alarm systems to remind the user to take the correct dose of their medication at the correct time. Most importantly, it keeps an electronic log of the time of dosage consumption by detecting the presence/absence of pills in the pillbox. This overcomes major limitations of other pillboxes with a logging function that are often too large to carry, contain a single compartment, or only record the time the container was opened rather than the presence or absence of pills. The proposed pillbox logger complements a wearable device under development for people with Parkinson's disease that continuously monitors impaired movement. The combination of the pillbox logger with the wearable sensor will permit clinicians to determine the response to oral therapies, which can be used to optimize therapy. People with PD consume similar pills throughout the day hence the pillbox logger has been designed to detect the presence/absence of pills in general in the pillbox rather than which specific pills are absent or present in the pillbox logger. This feature of the current design
Developing and Implementing a Cloud-Based Software Solution for Tracking Ureteral Stents: A Pilot Study (2020)

<b><i>Introduction:</i></b> As many as 12.5% of patients who undergo ureteral stent placement fail to have their stent removed in a timely manner. Because retained stents can be a source of substantial morbidity, there is a need for solutions to help urologists track their stented patients. <b><i>Materials and Methods:</i></b> We developed a cloud-based software that is agnostic to the device manufacturer and can be seamlessly integrated into the electronic health record (EHR). The software automatically registers patients who undergo ureteral stent placement and then follows them through their postoperative course to ensure timely follow-up for device removal. To validate our software's performance, we reviewed the medical records of patients who underwent stent placement for any indication at our institution between February 1, 2018, and February 28, 2018. <b><i>Results:</i></b> During our 1-month pilot study, a total of 51 ureteral stents were placed during 49 procedures that were performed on 46 patients. Our software effectively captured all of these procedures. It was able to properly distinguish 31 procedures where the patient who underwent stenting had follow-up scheduled before surgery. More importantly, it alerted our schedulers to 18 procedures for which no return visit had been scheduled. Furthermore, our software was able to register follow-up attendance, correctly identifying 10 procedures where patients failed to arrive. <b><i>Conclusion:</i></b> We describe a high-fidelity software solution for automated tracking of ureteral stents that is agnostic to the device manufacturer and can be seamlessly integrated into the EHR, causing minimal disruption to provider workflows.
Dissemination barriers to Ross River virus in Aedes vigilax and the effects of larval nutrition on their expression (1999)

Effects of larval nutrition on vector competence of the mosquito Aedes vigilax (Skuse) (Diptera: Culicidae) from Townsville, north Queensland, for Ross River virus (RR) were examined. Larvae were reared on three different diets to create three significantly different size classes of adult mosquito. These were fed on serial dilutions of RR and then sampled on alternate days so the progression of the virus through the mosquito could be examined. No differences of vector competence could be attributed to larval nutrition. Barriers to infection and the correlation between infection rate, viral titre and transmission of RR by Ae. vigilax were also examined. The mesenteronal barrier was the only infection barrier expressed. No correlation between viral titre and transmission was detected, but a strong correlation was found between salivary gland infection and transmission rate. From this it was possible to estimate that 98.7+/-1.3% of Ae. vigilax with infected salivary glands transmit RR.
Assessment methodology for human-exoskeleton interactions: Kinetic analysis based on muscle activation (2022)

During the development and assessment of an exoskeleton, many different analyzes need to be performed. The most frequently used evaluate the changes in muscle activations, metabolic consumption, kinematics, and kinetics. Since human-exoskeleton interactions are based on the exchange of forces and torques, the latter of these, kinetic analyzes, are essential and provide indispensable evaluation indices. Kinetic analyzes, however, require access to, and use of, complex experimental apparatus, involving many instruments and implicating lengthy data analysis processes. The proposed methodology in this paper, which is based on data collected <i>via</i> EMG and motion capture systems, considerably reduces this burden by calculating kinetic parameters, such as torque and power, without needing ground reaction force measurements. This considerably reduces the number of instruments used, allows the calculation of kinetic parameters even when the use of force sensors is problematic, does not need any dedicated software, and will be shown to have high statistical validity. The method, in fact, combines data found in the literature with those collected in the laboratory, allowing the analysis to be carried out over a much greater number of cycles than would normally be collected with force plates, thus enabling easy access to statistical analysis. This new approach evaluates the kinetic effects of the exoskeleton with respect to changes induced in the user's kinematics and muscular activation patterns and provides indices that quantify the assistance in terms of torque (AMI) and power (API). Following the User-Center Design approach, which requires driving the development process as feedback from the assessment process, this aspect is critical. Therefore, by enabling easy access to the assessment process, the development of exoskeletons could be positively affected.
Prognostic Impact of Peritransplant Serum Sodium Concentrations in Liver Transplantation (2019)

BACKGROUND Serum sodium (Na) is considered to reflect the severity of liver cirrhosis. In the last few years, much effort has been made to integrate this association into prognostic models after liver transplantation. The aim of this study was to investigate the associations between peritransplant Na and neurological complications, as well as short-term survival, after liver transplantation. MATERIAL AND METHODS A total of 306 liver transplantations between 2012 and 2015 were evaluated. Pre- and posttransplant sodium concentrations were investigated with regard to 3-month survival and incidence of posttransplant neurological complications, along with other factors present in the operative side of the recipient and donor. RESULTS The 3-month survival rate was 94%. Neither hyponatremia ( 145 mEq/L) at pretransplantion predicted 3-month survival. A large amount of intraoperative blood transfusion and a large delta Na showed a significant association with poor outcomes at 3 months. On multivariate analysis, the requirement of blood transfusion and warm ischemia time remained independent prognostic factors for 3-month mortality. Hyponatremia and a large delta Na tended to lead to the frequent development of neurological complications. These complications, secondary to rapid Na correction, were concerning and potentially led to a prolonged hospital stay and early mortality. CONCLUSIONS Rapid change in the sodium level might be caused by large amounts of blood transfusion products. This leads to a diminished short-term survival, as well as a higher rate of neurological complications.
Plasmodium yoeliiinhibitor of cysteine proteases is exported to exomembrane structures and interacts with yoelipain-2 during asexual blood-stage development (2013)

Plasmodium falciparum (Pf) blood stages express falstatin, an inhibitor of cysteine proteases (ICP), which is implicated in regulating proteolysis during red blood cell infection. Recent data using the Plasmodium berghei rodent malaria model suggested an additional role for ICP in the infection of hepatocytes by sporozoites and during liver-stage development. Here we further characterize the role of ICP in vivo during infection with Plasmodium yoelii (Py) and Pf. We found that Py-ICP was refractory to targeted gene deletion indicating an essential function during asexual blood-stage replication, but significant downregulation of ICP using a regulated system did not impact blood-stage growth. Py-ICP localized to vesicles within the asexual blood-stage parasite cytoplasm, as well as the parasitophorous vacuole, and was exported to dynamic exomembrane structures in the infected RBC. In sporozoites, expression was observed in rhoptries, in addition to intracellular vesicles distinct from TRAP containing micronemes. During liver-stage development, Py-ICP was confined to the parasite compartment until the final phase of liver-stage development when, after parasitophorous vacuolemembrane breakdown, it was released into the infected hepatocyte. Finally, we identified the cysteine protease yoelipain-2 as a binding partner of Py-ICP during blood-stage infection. These data show that ICP may be important in regulating proteolytic processes during blood-stage development, and is likely playing a role in liver stage-hepatocyte interactions at the time of exoerythrocytic merozoite release.
Obituary for Susan M. MacDonald, M.D. (2021)

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A proposal of semantic multimedia contents retrieval framework for Smart TV (2012)

The semantic search promises to provide more accurate results than the current keyword matching-based search by understanding user intent and the contextual meaning of terms based on knowledge base. However, the ordinary users have difficulty in using the complex formal query language and the knowledge base schema on Smart TV having the restricted UI/UX. So, it is needed to develop a semantic search system to interpret the meaning of simple user keywords and find the multimedia content users want for Smart TV. In this paper, we describe a framework for the semantic multimedia contents retrieval. It is ontological knowledge base-driven framework in the sense that the knowledge base plays a main role in the whole search process including keyword interpretation and contents search. We also present our prototype system developing to test our framework ideas.
Suppression Method of DC-offset in Transformer Current for Flying Capacitor Dual Active Bridge Converter at Changing Operation Mode (2019)

This paper proposes a modulation method to eliminate the DC-offset in transformer current at changing operation modes, which are square waveform, five-level waveform, and square waveform with half of the DC voltage. In the proposed modulation method, the update of phase-shift angle is divided into two steps. From the experiment, the peak of the transformer current due to the DC-offset current is reduced by up to 28.6% compared with the conventional method.
Situational Awareness in Complex Systems (1994)

Abstract : Decisions, whose appropriateness depends on knowledge and rules, are expected more or less effectively depending on the psychomotor skills of the operator. If these are sequential rather than parallel processes, and it seems to me that they must be even though they may be carried out very quickly, then in some cases we may be able to infer decision from action, and gestalt from decision, as long as we understand that the cognitive centroid of the individual operator is idiosyncratic and unknowable to some degree. Training can help to improve perception: it can also help to standardize the decisions taken in a given situation. The comprehension and integration of sensed data can also be improved by training, practice and criticism. The changes brought about by carefully targeted training can be observed and can also help us to underlying processes.
Electron scattering from laser-excited He atoms (1996)

Superelastic electron scattering has been observed, for the first time, from helium atoms in the state. The excited state has been prepared by optical pumping of a beam of metastable state atoms using a diode laser at , with the radiation directed in the scattering plane. The superelastic electron scattering intensity has been measured, at an incident energy of 9.2 eV and a scattering angle of , as a function of the linear polarization of the laser radiation. Comparison is made with a recent close-coupling calculation.
Identification of idarubicin in high throughput screen as a drug that selectively inhibits the proliferation of human smooth muscle cells versus endothelial cells (2013)

Goel, Shakti A. MB, BS; Guo, Lian-Wang PhD; Takayama, Toshio MD, PhD; Roenneburg, Drew A. BS; Guo, Song BS; Ananiev, Gene PhD; Hoffmann, Michael F. PhD; Kent, Craig K. MD, FACS Author Information
Contrasting effects of prostaglandins E2 and F2 alpha on sensitivity of the human cough reflex (1992)

Prostaglandins have been shown to influence the sensitivity of the cough reflex. To investigate putative mechanisms of this, we examined the effects of inhaled prostaglandins E2 (PGE2) and F2 alpha (PGF2 alpha) on human cough responses elicited by two challenges, low chloride solution and capsaicin, which may activate different neural pathways. Baseline cough challenges were followed after 2 h by five breaths of PGE2, PGF2 alpha, or citric acid as a control. Cough challenges were repeated after 1 min. Potentiation of capsaicin responses occurred after PGE2 (median increase 2 coughs/min, range 0-7, P less than 0.01) and PGF2 alpha (median increase 8 coughs/min, range -3 to 27, P less than 0.01) compared with control. The effect of PGF2 alpha was greater (P less than 0.05) than that of PGE2. Potentiation of low chloride responses also occurred after PGF2 alpha (median increase 7 coughs/2 min, range -1 to 19, P less than 0.01), but effects of PGE2 were insignificant against this challenge (median change -1 coughs/2 min, range -4 to 13). These data suggest that PGE2 and PGF2 alpha have different effects on the sensitivity of the human cough reflex, which may be relevant during airway disease.
Frost Susceptibility of Crushed Glass Used as Construction Aggregate (1997)

The frost susceptibility for 100% glass cullet specimens and 30% by weight glass cullet-aggregate specimens was determined using ASTM D 5918. The cullet has negligible to very low frost susceptibility, and it did not increase the frost susceptibility of the aggregate. Based on a comparison of grain size distributions of the cullet and aggregates with the work of others, we conclude that the material tested represents typical cullet for which other engineering properties have been determined; therefore, this information can be added to the current body of knowledge about the engineering properties of glass cullet.
Two-Phase Helico Axial Turbines (2003)

Abstract Following the development of two phase helico axial pumps in the seventies a R&amp;D program has recently been launched by IFP and DBGP for the development of two phase helico axial turbines. These turbines may be used in many process applications in replacement of let down valves for energy recovery but also to increase the cooling duty or the liquid production. They may also be used in systems including a two phase separator with single phase turbines or valves at its outlets in view of reducing the number of equipment, space and weight. These turbines, suitable for all gas fractions, may find applications in the hydrocarbon upstream field (HP/HT wells, fractured reservoirs, oil stabilisation, electricity production in remote areas) or in the hydrocarbon downstream field (refrigeration cycles, LNG, gas drying, solvent regeneration or hydrotreatment units). This wide potential field of applications requires helico axial turbines to be suitable for a broad range in flow rate, pressure, temperature and gas fraction. This has several consequences on the pump design, particularly, regarding the mass transfer occurring during the pressure let down and the volume change across a turbine or a hydraulic stage. A two phase helico axial turbine prototype will be tested, in single and two phase flows, during the second half of 2003 to confirm the expected hydraulic performance.
Synthesis and Biological Activity of Arylspiroborate Salts Derived from Caffeic Acid Phenethyl Ester (2015)

Two novel boron compounds containing caffeic acid phenethyl ester (CAPE) derivatives have been prepared and characterized fully. These new compounds and CAPE have been investigated for potential antioxidant and antimicrobial properties and their ability to inhibit 5-lipoxygenase and whether chelation to boron improves their biological activity. Sodium salt 4 was generally more active than ammonium salt 5 in the biological assays and surpassed the radical scavenging ability of CAPE. Compounds 4 and 5 were more active than CAPE and Zileuton in human polymorphonuclear leukocytes. These results clearly show the effectiveness of the synthesized salts as transporter of CAPE.
Mental Disorders Top The List Of The Most Costly Conditions In The United States: $201 Billion (2016)

Estimates of annual health spending for a comprehensive set of medical conditions are presented for the entire US population and with totals benchmarked to the National Health Expenditure Accounts. In 2013 mental disorders topped the list of most costly conditions, with spending at $201 billion.
Differential activation among five human inspiratory motoneuron pools during tidal breathing (2006)

Neural drive to inspiratory pump muscles is increased under many pathological conditions. This study determined for the first time how neural drive is distributed to five different human inspiratory pump muscles during tidal breathing. The discharge of single motor units (n = 280) from five healthy subjects in the diaphragm, scalene, second parasternal intercostal, third dorsal external intercostal, and fifth dorsal external intercostal was recorded with needle electrodes. All units increased their discharge during inspiration, but 41 (15%) discharged tonically throughout expiration. Motor unit populations from each muscle differed in the timing of their activation and in the discharge rates of their motor units. Relative to the onset of inspiratory flow, the earliest recruited muscles were the diaphragm and third dorsal external intercostal (mean onset for the population after 26 and 29% of inspiratory time). The fifth dorsal external intercostal muscle was recruited later (43% of inspiratory time; P < 0.05). Compared with the other inspiratory muscles, units in the diaphragm and third dorsal external intercostal had the highest onset (7.7 and 7.1 Hz, respectively) and peak firing frequencies (12.6 and 11.9 Hz, respectively; both P < 0.05). There was a unimodal distribution of recruitment times of motor units in all muscles. Neural drive to human inspiratory pump muscles differs in timing, strength, and distribution, presumably to achieve efficient ventilation.