gebhart/patrepeval huggingface dataset:
Self in motion: sensorimotor and cognitive mechanisms in gait agency (2013)

Acting in our environment and experiencing ourselves as conscious agents are fundamental aspects of human selfhood. While large advances have been made with respect to understanding human sensorimotor control from an engineering approach, knowledge about its interaction with cognition and the conscious experience of movement (agency) is still sparse, especially for locomotion. We investigated these relationships by using life-size visual feedback of participants' ongoing locomotion, thereby extending agency research previously limited to goal-directed upper limb movements to continuous movements of the entire body. By introducing temporal delays and cognitive loading we were able to demonstrate distinct effects of bottom-up visuomotor conflicts as well as top-down cognitive loading on the conscious experience of locomotion (gait agency) and gait movements. While gait agency depended on the spatial and temporal congruency of the avatar feedback, gait movements were solely driven by its temporal characteristics as participants nonconsciously attempted to synchronize their gait with their avatar's gait. Furthermore, gait synchronization was suppressed by cognitive loading across all tested delays, whereas gait agency was only affected for selective temporal delays that depended on the participant's step cycle. Extending data from upper limb agency and auditory gait agency, our results are compatible with effector-independent and supramodal control of agency; they show that both mechanisms are dissociated from automated sensorimotor control and that cognitive loading further enhances this dissociation.
A phosphatidylserine binding site in factor Va C1 domain regulates both assembly and activity of the prothrombinase complex (2008)

Tightly associated factor V(a) (FVa) and factor X(a) (FXa) serve as the essential prothrombin-activating complex that assembles on phosphatidylserine (PS)-containing platelet membranes during blood coagulation. We have previously shown that (1) a soluble form of PS (C6PS) triggers assembly of a fully active FVa-FXa complex in solution and (2) that 2 molecules of C6PS bind to FVa light chain with one occupying a site in the C2 domain. We expressed human factor V(a) (rFVa) with mutations in either the C1 domain (Y1956,L1957)A, the C2 domain (W2063,W2064)A, or both C domains (Y1956,L1957,W2063,W2064)A. Mutations in the C1 and C1-C2 domains of rFVa reduced the rate of activation of prothrombin to thrombin by FXa in the presence of 400 muM C6PS by 14 000- to 15 000-fold relative to either wild-type or C2 mutant factor rFVa. The K(d')s of FXa binding with rFVa (wild-type, C2 mutant, C1 mutant, and C1-C2 mutant) were 3, 4, 564, and 624 nM, respectively. Equilibrium dialysis experiments detected binding of 4, 3, and 2 molecules of C6PS to wild-type rFVa, C1-mutated, and C1,C2-mutated rFVa, respectively. Because FVa heavy chain binds 2 molecules of C6PS, we conclude that both C2 and C1 domains bind one C6PS, with binding to the C1 domain regulating prothrombinase complex assembly.
Auto-pooling: Learning to Improve Invariance of Image Features from Image Sequences (2013)

Learning invariant representations from images is one of the hardest challenges facing computer vision. Spatial pooling is widely used to create invariance to spatial shifting, but it is restricted to convolutional models. In this paper, we propose a novel pooling method that can learn soft clustering of features from image sequences. It is trained to improve the temporal coherence of features, while keeping the information loss at minimum. Our method does not use spatial information, so it can be used with non-convolutional models too. Experiments on images extracted from natural videos showed that our method can cluster similar features together. When trained by convolutional features, auto-pooling outperformed traditional spatial pooling on an image classification task, even though it does not use the spatial topology of features.
Saying it with songs: popular music and the coming of sound to Hollywood cinema (2014)

Acknowledgments Introduction Chapter 1. Singing a Song: The Culture and Conventions of Popular in the 1920s Chapter 2. Owning a Song: The Restructuring of Hollywood and Tin Pan Alley Chapter 3. Plugging a Song: The Discrete Charm of the Popular Song, From Broadway to Hollywood Chapter 4. Integrating a Song: The Threat to Narrative Plausibility Chapter 5. Curtailing a Song: Toward the Classical Background Score Conclusion: The Fate of the Motion Picture Song Appendix 1: Confirmatory License Issued by Publishers Protective Association (1929) Appendix 2: Tieups of Film and Music as Reported by Variety Appendix 3: Timeline of Relationships Between Film and Companies Appendix 4: Agreement between Al Dubin, The Vitaphone Corp., and Publishers Holding Corporation Appendix 5: Summary of Agreement between Vitaphone Corporation, M. Witmark & Sons, and Ray Perkins Bibliography Credits Index
A practical approach to determining the uncertainty of a pressure measurement system (1993)

The pressure measurement systems located at three propulsion component test stands at the Marshall Space Flight Center (MSFC) were evaluated for their specific measurement uncertainty levels. An elemental error source evaluation was performed to provide an analytical estimate of uncertainty. Applied loads tests were also conducted at the different MSFC test sites to derive an empirical estimate of uncertainty for the measurement system process. The analytical results are compared to those obtained empirically. The data from MFSC was also compared to data reported from other comparable test facilities. Methods for acquiring and processing the data from calibration, acquisition, and reduction error sources are also addressed.
Effect of coloured shade‐nets on plant leaf parameters and tomato fruit quality (2014)

These results show that red and pearl photo-selective nets create optimal growing conditions for the growth of the plant and produce fruits with thicker pericarp, the highest lycopene content, a satisfactory level of taste index and can be further implemented within protected cultivation practices.
Structure of the poxvirus decapping enzyme D9 reveals its mechanism of cap recognition and catalysis (2021)

SUMMARY Poxviruses encode decapping enzymes that remove the protective 5’ cap from both host and viral mRNAs to commit transcripts for decay by the cellular exonuclease Xrn1. Decapping by these enzymes is critical for poxvirus pathogenicity by means of simultaneously suppressing host protein synthesis and limiting the accumulation of viral dsRNA, a trigger for antiviral responses. Here we present the first high resolution structural view of the vaccinia virus decapping enzyme D9. This Nudix enzyme contains a novel domain organization in which a three-helix bundle is inserted into the catalytic Nudix domain. The 5’ mRNA cap is positioned in a bipartite active site at the interface of the two domains. Specificity for the methylated guanosine cap is achieved by stacking between conserved aromatic residues in a manner similar to that observed in canonical cap binding proteins VP39, eIF4E, and CBP20 and distinct from eukaryotic decapping enzyme Dcp2.
Berichtigung: Copper‐Catalyzed Synthesis of γ‐Amino Acids Featuring Quaternary Stereocenters (2017)

In Schema 2 dieser Zuschrift ist eine falsche Struktur für die vorgeschlagene Zwischenstufe C gezeigt: An das Lacton-O-Atom sollte kein Wasserstoffatom gebunden sein. Die korrekte Struktur für C ist hier abgebildet. Die Autoren bitten, dieses Versehen zu entschuldigen.
ChemInform Abstract: Temperature Effects on Intramolecular Electron Transfer Kinetics Under “Normal”, “Inverted”, and “Nearly Optimal” Conditions (1993)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Lack of Effect of Recombinant Human Growth Hormone on the In Vitro Activities of Antiretroviral Drugs against Human Immunodeficiency Virus Type 1 (2004)

We studied the effects of recombinant human growth hormone (r-hGH) on human immunodeficiency virus type 1 replication by growing both wild-type and drug-resistant variants of virus in the presence of various concentrations of eight different antiretroviral drugs. r-hGH had no significant effect on either viral replication or the 50% inhibitory concentrations of these compounds.
Non-contact surface vibration analysis using a monomode fibre optic interferometer incorporating an open air path (1985)

A very high sensitivity non-contacting vibration analysis system based upon a monomode fibre optic Mach Zehnder interferometer incorporating an open air path is described. The system was operated in both a closed loop limited tracking range (>105) homodyne mode and an effective infinite tracking range novel pseudo-heterodyne mode. For periodic signals, amplitude detection sensitivities of approximately 2*10-10 m at 10 Hz to 5*10-11 m at 10 kHz have been demonstrated for both modes of operation.
Increasing the resolving power of capillary electrophoresis through electroosmotic flow control using radial fields (1999)

A method for controlling the electroosmotic flow (EOF) in a capillary is reported using radial electric fields which vary along the length of the separation capillary. The magnitude of the control is compared to the control achieved using radial fields which remain constant along the length of the capillary. The effects of buffer concentration, buffer pH, capillary inner diameter, and capillary outer diameter on the range of control are also examined. The potential for increasing the resolving power of capillary electrophoresis (CE) through the use of radial field control of EOF is demonstrated through the separation of dansylated leucine and isoleucine. ©1999 John Wiley & Sons, Inc. J Micro Sep 11: 167–174, 1999
<title>Practical considerations for effective microendoscopy</title> (1991)

This paper reports on the application of angioscopic technology to the endoscopy of previously inaccessible body cavities. Necessary instruments including endoscopes, light sources, cameras, video recorders, monitors, and other accessories are described. Practical considerations for effective instrumentation are discussed. An overview of our clinical microendoscopic applications in more than 630 patients is presented.
A Methodology Based on NMR Spectroscopy for the Forensic Analysis of Condoms (2001)

Both solution and solid state Nuclear Magnetic Resonance (NMR) spectroscopic techniques have been used to determine differences in commercially available condoms. Whilst solid state NMR is useful for determining the polymer backbone, it is not useful for forensic analysis due to the commonality of the latex condom. However solution NMR spectra obtained following a simple extraction procedure using hexane, provides a fingerprint of the additives in the lubricants. Following the development of a flow chart, basing decisions on the presence of particular peaks present in the solution spectra, 33 of 38 condoms could be individualized. Samples were also analyzed after having the lubricant manually removed and soaking the condom in water for 3 to 24 h. These experiments were performed to simulate a case of the sample having been used and disposed of by flushing down the toilet, as may be experienced in a case of a sexual assault. The results indicated that the only significant water soluble component was polyethylene glycol. The overall results suggest that the method developed may be a quick and useful technique in characterizing condoms. The information obtained can be used to provide associative evidence between suspect and crime, and so be useful in sexual assault cases.
Plasma Levels of Soluble Receptor for Advanced Glycation End Products and Coronary Artery Disease in Nondiabetic Men (2005)

Objective— The receptor for advanced glycation end products (RAGE) is a cell surface receptor whose signaling pathway has been implicated in atherogenesis. RAGE has an endogenous secretory receptor form, called soluble RAGE (sRAGE), that could exert antiatherogenic effects by acting as a decoy. We sought to determine whether a decreased plasma level of sRAGE could be independently associated with the prevalence of coronary artery disease (CAD) in nondiabetic men. Methods and Results— Plasma levels of sRAGE were determined in 328 nondiabetic male patients with angiographically proved CAD and in 328 age-matched healthy controls. The concentration of sRAGE in plasma was significantly lower ( P &lt;0.0001) in CAD cases [median (interquartile range): 966 (658–1372) pg/mL] than in control subjects [1335 (936–1954) pg/mL]. In logistic regression analysis, the multivariate-adjusted odds ratio for the presence of CAD was 6.719 (95% confidence interval, 3.773 to 11.964; P &lt;0.0001) when the lowest quartile of the sRAGE level was compared with the highest quartile. Conclusions— Our findings indicate that low levels of sRAGE in plasma are independently associated with the presence of CAD in nondiabetic men and suggest that sRAGE is one of the clinically important molecules associated with atherosclerosis.
Intraoperative imaging of positron emission tomographic radiotracers using Cerenkov luminescence emissions. (2011)

Imaging the location and extent of cancer provides invaluable information before, during, and after surgery. The majority of "image-guided" methods that use, for example, positron emission tomography (PET) involve preoperative imaging and do not provide real-time information during surgery. It is now well established that the inherent optical emissions (Cerenkov radiation) from various β-emitting radionuclides can be visualized by Cerenkov luminescence imaging (CLI). Here we report the full characterization of CLI using the positron-emitting radiotracer 89Zr-DFO-trastuzumab for target-specific, quantitative imaging of HER2/neu-positive tumors in vivo. We also provide the first demonstration of the feasibility of using CLI for true image-guided, intraoperative surgical resection of tumors. Analysis of optical CLIs provided accurate, quantitative information on radiotracer biodistribution and tissue uptake that correlated well with the concordant PET images. CLI, PET, and biodistribution studies revealed target-specific uptake of 89Zr-DFO-trastuzumab in BT-474 (HER2/neu positive) versus MDA-MB-468 (HER2/neu negative) xenografts in the same mice. Competitive inhibition (blocking) studies followed by CLI also confirmed the in vivo immunoreactivity and specificity of 89Zr-DFO-trastuzumab for HER2/neu. Overall, these results strongly support the continued development of CLI as a preclinical and possible clinical tool for use in molecular imaging and surgical procedures for accurately defining tumor margins.
ChemInform Abstract: SYNTHESIS AND PHARMACOLOGICAL SCREENING OF 1,2,3‐TRIAZOLE DERIVATIVES OF NAPHTHALENE, QUINOLINE, PYRIDINE (1979)

Abstract Durch Umsetzung des Aminonaphthalins (I) mit Natriumnitrit und Natriumazid bzw. des Chlorchinolins (II) und des Chlorpyridins (V) mit Natriumazid erhält man die Azide (II), (IV) und (VI).
A Focused Crawler URL Analysis Algorithm based on Semantic Content and Link Clustering in Cloud Environment (2015)

Currently, the efficiency of the existing focused crawlers is not high because of their unsatisfactory precision. In this article, we analyze the URL analysis methods of the existing focused crawlers, and propose a URL analysis algorithm based on the semantic content and link clustering in cloud environment. In this algorithm, the download URLs are clustered with the philosophy of clustering on the basis of VSM to improve the precision of the focused crawler according to the correlation between download URLs and new URLs. The algorithm is evaluated on Heritrix3.10 compared with Best First Search algorithm and Shark Search algorithm. The experiment results demonstrate that the algorithm proposed can collect web pages related to the given topic accurately and effectively.Moreover, the algorithm has a good ability of learning which proves the possibility of this algorithm.
Evolved neural networks for HIV-1 co-receptor identification (2014)

HIV-1 infects a variety of cell types such as macrophages, T-cells and dendritic cells by expressing different chemokine receptors. R5 HIV-1 viruses use the CCR5 co-receptor for entry, X4 viruses use the CXCR4 co-receptor, and several viral strains make use of both co-receptors (a so-called “dual tropic” or R5X4 virus). Both X4 and R5X4 viruses are associated with late stage rapid progression to AIDS. It remains difficult to identify viral co-receptor type in advance of treatment, especially the R5X4 variety. In this paper we extended previous work to classify HIV-1 tropism using evolved neural networks and a larger set of HIV-1 sequences and features to improve overall classification accuracy.
Blind and semi-blind maximum likelihood techniques for multiuser multichannel identification (1998)

We investigate blind and semi-blind maximum likelihood techniques for multiuser multichannel identification. Two blind Deterministic ML methods based on cyclic prediction filters are presented [1]. The Iterative Quadratic ML (IQML) algorithm is used in [1] to solve it: this strategy does not perform well at low SNR and gives biased estimates due to the presence of noise. We propose a modification of IQML that we call DIQML to denoise it and explore a second strategy called Pseudo-Quadratic ML (PQML). As proposed in [2], PQML works well only at very high SNR. The solution we present here makes it work well at rather low SNR conditions and outperform DIQML. Like DIQML, PQML is proved to be consistent, asymptotically insensitive to the initialisation and globally convergent. Furthermore, it has the same performance as DML. A semi-blind extension combining these algorithms with training sequence based approaches is also studied. Simulations will illustrate the performance of the different algorithms which are found to be close to the Cramer-Rao bounds.
Diffusion of a small molecule in the cytoplasm of mammalian cells. (1984)

Electron spin resonance was used to measure the diffusion of a small (Mr 170) spin label in the aqueous cytoplasm of mammalian cells. Translational and rotational motion were determined from the same spectra. Based on measurements made in model systems, it was hypothesized that calculations of the apparent viscosity from either rotational or translational motion would distinguish between the effects of cytoplasmic viscosity or cytoplasmic structure on diffusion. The diffusion coefficient calculated from spin label collision frequency, averaged 3.3 X 10(-6) cm2/sec in several cell lines. It was greater in growing cells and in cells treated with cytochalasin B than in quiescent cells. The viscosity of the cytoplasm calculated from the translational diffusion coefficient or the rotational correlation time was 2.0-3.0 centipoise (1 P = 0.1 Pa X sec), about 2-3 times that of the spin label in water. Therefore, over the dimensions measured by the technique, 50-100 A, solvent viscosity appears to be the major determinant of particle movement in cells under physiological conditions. However, when cells were subjected to hypertonic conditions, the translational motion decreased by 67%, while the rotational motion changed less than 20%. These data suggested that the decrease in cell volume under hypertonic conditions was accompanied by an increase in cytoplasmic barriers and a decrease in the spacing between existing components. In addition, a comparison of reported values for diffusion of a variety of molecules in water and in cells indicates that cytoplasmic structure plays an important role in the diffusion of proteins such as bovine serum albumin.
High‐Temperature Oxidation of Boron Nitride: II, Boron Nitride Layers in Composites (1999)

The oxidation of BN composite interphases was examined with a series of model materials. Oxidation was examined in both low‐water‐vapor (∼20 ppm H 2 O/O 2 ) environments at 900°C and high‐water‐vapor (1% and 10% H 2 O/O 2 ) environments at 700° and 800°C. The low‐water‐vapor case was explored with layered BN/SiC materials. This case was dominated by borosilicate glass formation, and the 20 ppm water vapor gradually removed the boron from the glass, leaving a larger amount of SiO 2 than would be expected from simple SiC oxidation. Layered SiC/BN/SiC materials were also used to study low‐water‐vapor oxidation effects within the composite. The high‐water‐vapor case was explored with SiC/BN/SiC minicomposites, and it was dominated by volatilization of BN as HBO 2 ( g ), H 3 BO 3 ( g ), and H 3 B 3 O 6 ( g ). A model for recession of the BN fiber coating was developed based on the gas‐phase diffusion of these species out of the annular region around the SiC fiber and concurrent sealing of this annular region by oxidation.
Effect of dietaryYucca schidigeraextract on growth, total ammonia-nitrogen excretion and haematological parameters of juvenile striped catfishPangasianodon hypophthalmus (2012)

A feeding trial with striped catfish, Pangasianodon hypophthalmus was performed to determine the effect of Yucca schidigera in practical diet on the growth, feed utilization, body composition, total ammonia–nitrogen (TAN) excretion and haematological parameters. A diet with fish meal as the main protein source without yucca extract was used as the control diet (Diet 1). Four diets were formulated with 0.075 (Diet 2), 0.1 (Diet 3) and 0.15 (Diet 4)% of yucca extract respectively. Fifteen fish per tank (initial mean weight 1.78 ± 0.05 g) were randomly allocated to 15 fibreglass tanks (80-L) connected to a freshwater closed recirculation system (temperature 29.7 ± 1.0°C). The experimental diets were tested in triplicates for 12 weeks. The specific growth rate of fish fed Diet 4 was significantly higher when compared with fish fed Diet 1. The growth of fish fed diets Diet 2 and Diet 3 were not significantly different compared with fish fed the Diet 1. Striped catfish fed Diet 4 had significantly lower feed conversion ratio compared with fish fed Diet 1 and Diet 2 (P < 0.05).The incorporation of high level Yucca schidigera extract in the diets reduced TAN compared with Diet 1. Dietary inclusion of Yucca extract levels did not significantly affect the biometric parameters or whole body proximate composition of the striped catfish (P > 0.05). The PCV (%) in fish significantly increased with high levels of Yucca inclusion (Diet 4) compared with control diet. Fish fed Diet 4 showed significantly higher haemoglobin levels than Diet 1 (P < 0.05). The results indicate that dietary inclusion of Yucca schidigera extract is promising as a feed additive that could improve growth performance and some haematological parameters and the best Yucca schidigera level was 0.15%.
Ion beam deposited silicon carbide on glass optics and replica gratings (1984)

Get PDF Email Share Share with Facebook Share on X Post on reddit Share with LinkedIn Add to Mendeley Add to BibSonomy Share with WeChat Get Citation Copy Citation Text David L. Windt and Bernhard Bach, "Ion beam deposited silicon carbide on glass optics and replica gratings," Appl. Opt. 23, 3047-3049 (1984) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
System-chip test strategies (1998)

A major challenge in realizing core-based system-chips is theadoption of adequate test and diagnosis strategies. This paperfocuses on the current industrial practices in test strategiesfor system-chips. It discusses the challenges in testingembedded cores, the testing requirements for individualcores, and their test access mechanisms. It also covers theintegrated test strategies for system-chips based on reusablecores. In addition to the state-of-the-art practices intestability schemes, this paper covers the currentstandardization efforts for embedded core test interfacemechanisms.