gebhart/patrepeval huggingface dataset:
Inheritance of Resistance to Orobanche cernua Loefl. in Six Sunflower Lines (1999)

Sunflower ( Helianthus annuus L.) is severely affected by broomrape ( Orobanche cernua Loefl.) in the main crop areas of the Old World. The appearance of new virulent broomrape populations has prompted the search for new sources of resistance. The objectives of this study were to elucidate the inheritance of sources of resistance from different origins and to determine allelic relationships between the resistance genes. Six resistant sunflower lines (one of them with resistance gene Or 5 ), two susceptible lines, the F 1 crosses between resistant and susceptible lines and resistant and resistant lines, and the F 2 and BC 1 generations were evaluated for broomrape resistance with the widespread highly virulent population SE 194. Genetic ratios from segregating generations indicated that resistance to 0. cernua in these lines was conferred by a single dominant gene. None of the crosses between resistant lines produced susceptible F 2 or BC 1 plants. However, the reaction of the resistant lines to broomrape populations from different areas and years showed differences to new highly virulent populations. Only two lines were resistant to all populations, indicating that resistance in these lines was conferred by additional dominant alleles at the Or locus or by a cluster of very tightly linked non‐allelic genes. The resistance found in the two cultivated lines against the new populations, which overcome the Or , resistance gene, is an important finding and will aid the development of new resistant cultivars since the current resistant hybrids are based on this gene. Results from this study can also be used to establish differential lines against the new broomrape populations.
Impairment of renal function in Schnitzler’s syndrome (2006)

The list of multisystem diseases involving both kidney and skin is long and includes immunologic disorders like systemic lupus erythematodes, a broad variety of vasculitides, metabolic disorders like diabetes mellitus, and infectious diseases. The present work describes the first case of renal failure due to Schnitzler's syndrome, a rare entity characterized by the association of generalized chronic urticaria, monoclonal IgM gammopathy, and osteosclerotic lesions. The described patient experiences improvement of renal function after treatment with the chimeric anti-CD20 antibody rituximab, indicating that the impairment of renal function might be mediated by B-lymphocytes. Renal insufficiency is known to be a potential complication of hypocomplementemic urticarial vasculitis. The present case reveals that it can occur in normocomplementemic urticarial vasculitides as well. Schnitzler's syndrome is a rare but probably underdiagnosed syndrome. It should be considered in the differential diagnosis of rash and coincidental renal failure of unknown origin. Immunofixation of immunoglobulins constitutes the crucial diagnostic step, since monoclonal gammopathy is a constant clinical sign in this entity.
Direct observation of the strength of plasmon-longitudinal optical phonon interaction in n-type GaAs (2006)

The screening of longitudinal optical phonons by plasmons is investigated by time-resolved visible pump-mid-infrared probe transmission measurements in a series of light to highly doped n-type GaAs wafers. The reduced relaxation of photogenerated carriers is strongly correlated to the coupling between longitudinal optical phonons and background plasmons as suggested by the variation of the phonon strength over the doping range. The critical plasmon density at which the optical phonons were effectively screened, thereby reducing the carrier relaxation, was determined to be Nc∼1×1018cm−3.
Blinatumomab is associated with favorable outcomes in patients with B‐cell lineage acute lymphoblastic leukemia and positive measurable residual disease at a threshold of 10−4 and higher (2022)

The presence of measurable residual disease (MRD) is the strongest predictor of relapse in acute lymphoblastic leukemia (ALL). We conducted a prospective, single-arm, phase II study in adults with B-cell ALL with MRD ≥1 × 10<sup>-4</sup> after ≥3 months from the start of frontline therapy or one month from any salvage therapy. Blinatumomab was administered at a standard dosing of 28 micrograms daily as a continuous infusion for up to five cycles and up to four additional maintenance cycles. Thirty-seven patients with a median age of 43 years (range, 22-84 years) were treated. Twenty-seven patients (73%) were treated in first complete remission (CR) and 10 patients (27%) in second CR and beyond. Eighteen patients (49%) had Philadelphia-chromosome positive ALL and received concomitant tyrosine kinase inhibitor therapy. Twenty-three patients (62%) had a baseline MRD ≥10<sup>-3</sup> . A median of three cycles (range, 1-9 cycles) were administered. Overall, 27 patients (73%) achieved MRD-negative remission. With a median follow-up of 31 months (range, 5-70 months), the estimated 3-year relapse-free survival (RFS) rate was 63% (95% confidence interval [CI], 43%-77%) and overall survival (OS) rate 67% (95% CI, 46%-81%). These rates were 51% (95% CI, 27%-70%) and 61% (95% CI, 36%-78%) in patients with baseline MRD ≥1 × 10<sup>-3</sup> , and 83% (95% CI, 45%-95%) and 77% (95% CI, 32%-95%) in patients with baseline MRD <10<sup>-3</sup> respectively. The rates of adverse events were consistent with previous studies of blinatumomab. In summary, blinatumomab induced MRD negativity in most patients and resulted in high rates of RFS and OS. This study is registered at www.clinicaltrials.gov as #NCT02458014. Funding was provided by Amgen Inc.
A Dual-Band Integrated Network Analyzer For RF Bio Sensing Application (2020)

RF bio-sensing is often utilized for the detection of bio-samples by using the concept of shift in resonant frequency. It is widely reported that the shift in resonant frequency is narrower compared to the bandwidth of the device used for measuring this shift. As a result, wideband Vector Network Analyzer (VNA) proves to be an overkill and instead a narrowband measurement setup can fulfill this requirement. Therefore, in this paper, an integrated solution for the detection of materials having varying permittivities is presented. A Dual-Band Six Port Reflectometer (DBSPR) is proposed and designed using planer microstrip line technology for the purpose of characterizing the sensor using reflection and transmission coefficient. A Complimentary Split Ring Resonator (CSRR) based sensor having an unloaded resonance frequency of 2.3 GHz is utilized as a test set. The designed DBSPR operates at 1.12 GHz and 2.26 GHz with a 10dB bandwidth of 254 MHz and 215 MHz respectively. The DBSPR and CSRR sensor are integrated using a microstrip line. The integrated device is tested for two different materials having a permittivity of 2.3 and 4.3. A shift of 118 MHz is observed between these materials and thus shows the potential usefulness of the proposed setup.
Optimal Energy Management in a Range Extender PHEV Using a Cascaded Dynamic Programming Approach (2018)

Dynamic programming is widely used to benchmark the performance of a hybrid electric vehicle. It is also well documented that it is a very computationally heavy procedure depending on the number of states and control inputs in the problem formulation. In this paper we investigate the possibility of reduction in the computational time by splitting the number of states and control inputs between two models and applying dynamic programming individually, using the output of one as an input to the other and hence cascading the two models. A range extended hybrid electric vehicle powertrain architecture is modeled with four states and four control inputs, which is considered as the full model. Further, the states and control inputs of the battery and engine are separated from the other states, splitting them between the two new DP models. The vehicle performance estimated from this ‘cascaded models approach’ is compared with that from the full model. Initial comparisons show a very good match with minor differences in performance and considerable a reduction in computation time from around 6 hours to around a minute.
Hypoxia-selective inhibition of angiogenesis development by NAMI-A analogues (2016)

The antimetastatic ruthenium(III) complex (H<sub>2</sub>Im)[trans-RuCl<sub>4</sub>(HIm)(DMSO)] (NAMI-A) as well as its two analogues (H<sub>2</sub>Ind)[trans-RuCl<sub>4</sub>(HInd)(DMSO)] (Ru-Ind) and (HIsq)[trans-RuCl<sub>4</sub>(Isq)(DMSO)] (Ru-Isq) (HIm-imidazole, HInd-indazole, Isq-isoquinoline, DMSO-dimethyl sulfoxide) were tested for their effect on endothelial cell functions in vitro on human skin microvascular endothelial cells (HSkMEC) and human endothelial progenitor cells (HPEC-CB.2) under normoxic (21 % O<sub>2</sub>) and hypoxic (1 % O<sub>2</sub>) conditions. All studied complexes showed very low cytotoxicity profiles towards both mature microvascular and precursor endothelial cells (ECs), independently of oxygen concentration. Among tested compounds Ru-Ind exhibited the highest cytotoxicity. The antiangiogenic activity of ruthenium complexes was evaluated for their influence on pseudo-vessels formation by microvascular endothelial cells (HSkMEC) because of their involvement in melanoma progression. Our studies indicated that Ru-Ind and Ru-Isq exhibited hypoxia- and dose-dependent-inhibition of angiogenesis on Matrigel™. Significant hypoxia-selective downregulation of pseudo-vessels formation by Ru-Isq correlates with efficient inhibition of cell motility. Interestingly, in the applied concentration doses migration of endothelial cells was also inhibited by NAMI-A, but the pseudo-vessels formation on Matrigel™ was unaffected. Angiogenesis-related genes expression profile for both mature and precursor ECs indicated that inhibition of angiogenesis, mainly due to Ru-Isq, as compared to NAMI-A and Ru-Ind correlated with downregulation of CD31 and CD144 expression and upregulation of NOTCH4 expression in mature ECs, which is essential for endothelial cell motility and stalk cells organization control. The hypoxia-selective antiangiogenic activity of Ru-Ind and Ru-Isq, NAMI-A analogues makes them potent antimetastatic therapeutics for their selective action in hypoxia which controls tumor pathologic angiogenesis.
Recycled Carbon Nanofiber-Polypropylene Nanocomposite: A Step towards Sustainable Structural Material Development (2022)

Plastic products play a significant role in fulfilling daily necessities, but the non-decomposable nature of plastic leads to inescapable environmental damage. Recycling plastic material is the most appropriate solution to avoid pollution and short product lifespan. The present study shows the recycling effect on carbon nanofiber (CNF) reinforced polypropylene (PP) nanocomposite to attain the purpose of reuse and sustainability. 30 wt% CNF melt-blended with polymer and PP-nanocomposites were fabricated using the injection molding technique. PP-CNF nanocomposites were recycled, and mechanical, thermal, and morphological properties were investigated. Three-point bending and tensile testing showed a low decrement of ~1% and ~5% in bending and tensile strength after recycling 30 wt% PP-CNF nanocomposites. Scanning electron microscopy (SEM) images show that the alignment of CNF was disturbed after recycling due to the decrement in the aspect ratio of CNF. Differential scanning calorimetry (DSC) and X-ray diffraction (XRD) showed that the crystallinity of PP increases with recycling. The lowering of interfacial interaction between CNF and PP after recycling was studied by a stress-controlled rheometer. The decrement in mechanical properties of PP-CNF nanocomposite is not significant due to CNF reinforcement; hence, it can be reused for the same or other structural applications.
DTC Method for Vector Control of 3-Phase Induction Motor under Open-Phase Fault (2015)

Three-phase Induction Motor (IM) drives are widely used in industrial equipments. One of the essential problems of 3-phase IM drives is their high speed and torque pulsation in the fault conditions. This paper shows Direct Torque Control (DTC) strategy for vector control of a 3-phase IM under open-circuit fault. The objective is to implement a solution for vector control of 3-phase IM drives which can be also used under open-phase fault. MATLAB simulations were carried out and performance analysis is presented. DOI:  http://dx.doi.org/10.11591/telkomnika.v13i2.6910 Full Text: PDF
Spatial control of transgene expression in rice (Oryza sativa L.) using the GAL4 enhancer trapping system (2005)

We used enhancer trapping with the GAL4 transcriptional activator from yeast to obtain spatial control of transgene expression in all organs of the model monocotyledonous species rice (Oryza sativa L. cv. Nipponbare). Our T-DNA enhancer trapping cassette consisted of two principle components: (1) the minimal promoter-equipped gal4 gene placed adjacent to the right border, and (2) the green fluorescent protein gene (gfp) fused to the upstream activation sequence element (UAS) to which GAL4 binds and activates expression, so that gfp expression corresponds to gal4 expression. Agrobacterium-mediated integration of the cassette into the rice genome often brings the gal4 gene under transcriptional control of local genomic enhancers and promoters, resulting in gal4/gfp expression patterns ranging in specificity from single-cell types to constitutive expression. We produced more than 13 000 enhancer trap lines with this cassette and screened T(0) adult plants (1982 lines), T(1) seed (2684 lines) and T(1) seedlings (2667 lines) for gfp expression. Approximately 30% of the lines produced GFP, and we identified lines with gfp expression in specific cell types of all major organs of the rice plant. Subsequently, using the GUS reporter gene (uidA), we demonstrated that UAS:geneX constructs can be transactivated in specific cell types where gal4 and gfp are expressed, thus providing an excellent system for the manipulation of gene expression and physiological function in specific cell types of rice.
Thermal and Mechanical Properties of Poly(lactic acid) Specimens Fabricated by Various Equal-channel Angular Extrusion Processes (2011)

다양한 방식의 등통로각압축공정으로 생분해성 고분자인 폴리젖산수지 시편을 가공하여 각 공정 방식에 따른 시편들의 열 및 기계적 물성의 변화를 조사하였다. 각각 A, BC, C 세 가지의 시편 재 주입 방식과 1, 2, 4의 가공 횟수를 조합한 7개의 시편들을 제작하고, 각 시편의 녹는점, 열분해온도와 같은 열물성을 시차주사열량분석기와 열무게분석기를 사용하여 측정하였다. 시편의 응력변형의 변화를 경도 시험기를 사용하여 측정하고, 각 시편 절단면의 내부 미세구조를 주사전자현미경을 사용하여 관찰하였다. 관찰된 내부 미세구조는 경도시험결과를 설명하는데 정성적인 뒷받침이 되었다. 그 결과 PLA-P2A의 내부 미세 구조가 가장 치밀하고 촘촘히 겹쳐져 있음으로 인하여 내부 응력변형도 가장 많이 관찰되었다. We fabricated rod-like poly(lactic acid)(PLA) specimens through applying various methods of equal-channel angular extrusion(ECAE) process and investigated the change of thermal and mechanical properties of specimens before and after each ECAE process. Combining three re-injection routes(A, BC, and C) and three pass counts(1, 2 and 4) allowed us to fabricate 7 different PLA specimens. Thermal properties of each specimen were measured by both differential scanning calorimeter and thermo-gravimetric analyzer. Shear strains of each specimen with respect to applied loads were measured by indentation hardness tester. Field emmision scanning electron microscopy was used to observe internal microstructure of cross-section of each specimen. The observed microstructures qualitatively supported the explanation of hardness test results. Among 7 specimens, PLA-P2A showed the biggest shear strain probably due to its dense microstructure.
The effect of multichannel dynamic compression on speech intelligibility (1995)

In the recent literature on dynamic compression in hearing aids, a controversial discussion about the benefit of multichannel compression with short time constants has been raised. In this paper, some experimental results are contributed to the discussion: For low signal-to-noise ratios, a detrimental effect of fast multichannel compression on speech intelligibility in normal hearing listeners is found. However, a distinct degradation in speech quality and virtually no decrease in speech intelligibility is observed for comparatively high signal-to-noise ratios and compression ratios of up to 3. Since the predictions of the Speech Transmission Index deviate substantially from these results, its applications as an objective measure of intelligibility may not be extended to compressed speech.
Time-resolved single dopant charge dynamics in silicon (2016)

As the ultimate miniaturization of semiconductor devices approaches, it is imperative that the effects of single dopants be clarified. Beyond providing insight into functions and limitations of conventional devices, such information enables identification of new device concepts. Investigating single dopants requires sub-nanometre spatial resolution, making scanning tunnelling microscopy an ideal tool. However, dopant dynamics involve processes occurring at nanosecond timescales, posing a significant challenge to experiment. Here we use time-resolved scanning tunnelling microscopy and spectroscopy to probe and study transport through a dangling bond on silicon before the system relaxes or adjusts to accommodate an applied electric field. Atomically resolved, electronic pump-probe scanning tunnelling microscopy permits unprecedented, quantitative measurement of time-resolved single dopant ionization dynamics. Tunnelling through the surface dangling bond makes measurement of a signal that would otherwise be too weak to detect feasible. Distinct ionization and neutralization rates of a single dopant are measured and the physical process controlling those are identified.
A Low Overhead On-Chip Path Delay Measurement Circuit (2009)

In this paper, we present a novel on-chip path delay measurement circuit for efficiently detecting and debugging of delay faults in the fabricated integrated circuits. Several delay stages are employed in the proposed circuit, whose delay ranges are increased by a factor of two gradually from the last to the first delay stage. Thus, the proposed method can achieve a large delay measurement range with a small quantity of delay stages. Experimental results show that a significant reduction in both delay measurement time and area overhead can be obtained compared to the previous Vernier Delay Line based delay measurement schemes. In addition, by conducting delay compensation, the proposed method can achieve both improved delay measurement resolution and measurement accuracy.
Shared autonomous vehicles and their potential impacts on household vehicle ownership: An exploratory empirical assessment (2018)

Emerging transportation technologies have the potential to significantly reshape the transportation systems and household vehicle ownership. Key among these transportation technologies are the autonomous vehicles, particularly when introduced in shared vehicle fleets. In this paper, we focus on the potential impact that fleets of shared autonomous vehicles might have on household vehicle ownership. To obtain initial insights into this issue, we asked a sample of university personnel and members of the American Automobile Association as to how likely they would consider relinquishing one of their household's personal vehicles if shared autonomous vehicles were available (thus reducing their household vehicle ownership level by one). For single-vehicle households, this would be relinquishing their only vehicle, and for multivehicle households (households owning two or more vehicles) this would be relinquishing just one of their vehicles. Possible responses to the question about relinquishing a household vehicle if shared autonomous vehicles are present are: extremely unlikely, unlikely, unsure, likely, and extremely likely. To determine the factors that influence this response, random parameters ordered probit models are estimated to account for the likelihood that considerable unobserved heterogeneity is likely to be present in the data. The findings show that a wide range of socioeconomic factors affects people's likelihood of vehicle relinquishment in the presence of shared autonomous vehicles. Key among these are gender effects, generational elements, commuting patterns, and respondents' vehicle crash history and experiences. While people's opinions of shared autonomous vehicles are evolving with the continual introduction of new autonomous vehicle technologies and shifting travel behavior, the results of this study provide important initial insights into the likely effects of shared autonomous vehicles on household vehicle ownership.
LOP28 (2015)

Plastic and Reconstructive Surgery: August 2015 - Volume 136 - Issue 2S - p 443 doi: 10.1097/01.prs.0000470720.13880.f7
Transient cold shock induces the heat shock response upon recovery at 37 degrees C in human cells. (1994)

We evaluated the effects of a transient cold shock followed by recovery and incubation at 37 degrees C on the regulation of heat shock gene expression in the IMR-90 human diploid fibroblasts and HeLa cells in tissue culture. We showed that preincubation of cells at 4 degrees C induced the synthesis and accumulation of the heat shock proteins (HSPs) upon recovery at 37 degrees C, and the degree of this induction was directly related to the time that the cells spent at 4 degrees C. Assays on the abundance of the hsp 70 transcript, the hsp 70 gene promoter activity, and the trimerization and activation of heat shock factor (HSF) to bind to its consensus heat shock element (HSE) provided evidence that this induction of the heat shock response in cells recovering from a transient cold shock is attributable to a transcriptional event mediated by the activation of HSF. Further, the induction was a response to the temperature upshift from 4 to 37 degrees C as opposed to the 4 degrees C treatment itself; quantitation of the HSE-binding activity of cells incubated at 4 degrees C without recovery and incubation at 37 degrees C gave no evidence of an activated response. Analysis of the effects of protein synthesis inhibitors demonstrated that neither cycloheximide nor puromycin was effective in blocking the induction of HSE-binding activity in cells recovering from a transient cold shock. Experiments on the time course and temperature dependence of this induction of HSE-binding activity showed that the onset, magnitude, and duration of this induction were directly proportional to the severity of the cold stress (measured by time and temperature). We discuss the possible mechanism(s) involved in this induction of the heat shock genes at 37 degrees C by a transient cold shock and the biological implications of this observation.
Three-dimensional optoelectronic crossbar switch (2002)

High-speed operation of free-space optical interconnect for a three-dimensional optoelectronic crossbar switching has been analyzed. System architecture, transmitter and receiver design are presented. The effect of ghost talk caused by the superposition of the delayed reflections of the original signal due to the multiple propagation of the wave between the vertical-cavity surface-emitting laser (VCSEL) and metal-semiconductor-metal (MSM) detector has been analyzed. The study indicates that even in the presence of significant amount of ghost talk a high performance free-space optical interconnect can be realized in this system by employing a receiver architecture that allows for DC level adjustment of the signal at the input of the transimpedance amplifier stage.
Dipstick Pseudohematuria: Unnecessary Consultation and Evaluation (2009)

Positive dipstick heme tests should always be confirmed by microscopic urinalysis before urological referral or evaluation. Education of referring physicians regarding the American Urological Association guidelines could possibly help limit costly and potentially harmful, unnecessary evaluation of patients without true microhematuria.