gebhart/patrepeval huggingface dataset:
AMCTD: Adaptive Mobility of Courier Nodes in Threshold-Optimized DBR Protocol for Underwater Wireless Sensor Networks (2013)

In dense underwater sensor networks (UWSN), the major confronts are high error probability, incessant variation in topology of sensor nodes, and much energy consumption for data transmission. However, there are some remarkable applications of UWSN such as management of seabed and oil reservoirs, exploration of deep sea situation and prevention of aqueous disasters. In order to accomplish these applications, ignorance of the limitations of acoustic communications such as high delay and low bandwidth is not feasible. In this paper, we propose Adaptive mobility of Courier nodes in Threshold-optimized Depth-based routing (AMCTD), exploring the proficient amendments in depth threshold and implementing the optimal weight function to achieve longer network lifetime. We segregate our scheme in 3 major phases of weight updating, depth threshold variation and adaptive mobility of courier nodes. During data forwarding, we provide the framework for alterations in threshold to cope with the sparse condition of network. We ultimately perform detailed simulations to scrutinize the performance of our proposed scheme and its comparison with other two notable routing protocols in term of network lifetime and other essential parameters. The simulations results verify that our scheme performs better than the other techniques and near to optimal in the field of UWSN.
Synthesis of Fluoro-Functionalized Mesoporous Silica and Application to Fluorophilic Separations (2007)

Fluorocarbon-functionalized mesoporous silica is synthesized by the co-condensation of tetraalkoxysilane and fluoro-functionalized alkoxysilane precursors using a cationic fluorocarbon surfactant, C6F13C2H2NC5H5Cl (HFOPC) and C8F17C2H2NC5H5Cl (HFDePC), or a traditional hydrocarbon surfactant (C16H33N(CH3)3Br, CTAB) as templates. Fluorocarbon functionalization decreases the silica pore order, pore size, and surface area. The chain length of the fluorocarbon functional precursor and the surfactant template affects the pore order, the materials textural properties, and the fluorocarbon incorporation. Matching a fluorocarbon surfactant with a fluorocarbon functional precursor does not improve functional group incorporation; the incorporation of the perfluoro-octyl functional group is greater in CTAB-templated silica than in HFOPC-templated silica. The application of these mesoporous silica powders to fluorous separations is demonstrated using hydrocarbon and fluorocarbon-tagged anthraquinones. Dye elution through a packed column of mesoporous silica occurs in a narrower band than that for fluorocarbon-functionalized silica gel, consistent with the high fluorocarbon content and smaller pore and particle sizes of the mesoporous material.
Simple criterion of importance of laminar flame instabilities in premixed turbulent combustion of mixtures characterized by low Lewis numbers (2023)

By (i) highlighting the mitigation effect of strain rates on laminar flame instabilities and (ii) comparing peak growth rates of laminar flame instabilities with strain rates generated by small-scale turbulent eddies, a simple criterion of importance of the influence of the instabilities on an increase in premixed flame surface area in turbulent flows is suggested. The criterion implies that, even in lean hydrogen-air mixtures, laminar flame instabilities can significantly affect the flame area only in weak or moderate turbulence (the Karlovitz number defined using laminar flame speed, thermal flame thickness, and Kolmogorov time scale is on the order of 10 or less under room conditions).
Lactobacillus rhamnosus GG supplementation attenuates chronic‐alcohol induced liver injury by inhibiting hepatocyte apoptosis (2012)

Previous studies have demonstrated that chronic alcohol consumption induces liver injury, which is associated with ethanol metabolism‐mediated oxidative stress and apoptotic cell death, in human and experimental animals. As probiotic supplementation is known to reduce the formation of reactive oxygen species (ROS) and reactive nitrogen species (RNS) in the intestine and the liver in the mice chronically fed alcohol, the present study was aimed to investigate whether probiotic supplementation could inhibit alcohol‐induced hepatic apoptosis in mice. C57BJ/6N mice were fed the Lieber deCarli diet containing 5% alcohol with or without Lactobacillus rhamnosus GG (LGG) for 4 weeks. LGG supplementation completely inhibited the chronic alcohol consumption‐increased hepatic apoptosis measured by TUNEL assay along with ROS and RNS production. The anti‐apoptotic effect of LGG on the liver of the alcohol‐treated mice was further confirmed by measuring Caspase 3 activation, and the protein levels of anti‐/pro‐apoptotic proteins, such as Bcl‐2 and Bax, and death signal proteins, such as FasR and FasL. These results indicate that LGG treatment reduces alcohol‐induced hepatic apoptotic cell death by multiple mechanisms, and provides a mechanistic insight for utilization of probiotics for the treatment of ALD.
Packing the most onto your cloud (2009)

Parallel dataflow programming frameworks such as Map-Reduce are increasingly being used for large scale data analysis on computing clouds. It is therefore becoming important to automatically optimize the performance of these frameworks. In this paper, we deal with one particular optimization problem, namely scheduling sets of Map-Reduce jobs on a cluster of machines. We present a scheduler that takes job characteristics into account and finds a schedule that minimizes the total completion time of the set of jobs. Our scheduler decides on the number of machines to assign to each job, and it tries to pack as many jobs on the machines as the machine resources can support. To enable flexible assignment of jobs onto machines, we run the Map-Reduce jobs in virtual machines. Our scheduling problem is formulated as a constrained optimization problem, and we experimentally demonstrate using the Hadoop open source Map-Reduce implementation that the solution to this problem results in benefits up to 30%.
Evidence That Pathogenic Transglutaminase 2 in Celiac Disease Derives From Enterocytes (2020)

The enzyme transglutaminase 2 (TG2) plays a key role in celiac disease (CeD) pathogenesis through generation of immunogenic, deamidated gluten T-cell epitopes, and as a target of autoantibodies. The disorder is caused by a maladaptive immune response to cereal gluten proteins, and accumulating evidence suggest that interactions between gluten-specific T cells and TG2-specific B cells are important for driving the disease. A big remaining question is where in the body TG2, which is a cytosolic protein, encounters gluten and engages the immune system.
Analysis of HIV Type 1 gp41 and Enfuvirtide Susceptibility among Men in the United States Who Were HIV Infected Prior to Availability of HIV Entry Inhibitors (2009)

We analyzed HIV gp41 from 195 men in the United States who were HIV-1 infected between 1999 and 2002, before enfuvirtide (ENF) was approved for clinical use in the United States. gp41 genotyping results were obtained for 175 samples. None of the samples had major ENF resistance mutations. Six (3.4%) samples had minor ENF resistance mutations in the HR1 region (V38G, N43K, L44M, L45M). Twenty-eight (16%) samples had the N42S polymorphism, which is associated with ENF hypersusceptibility. Accessory mutations in the HR2 region were identified in some samples (E137K, S138A). Five of the six samples with HR1 resistance mutations were analyzed with a phenotypic assay; one sample had reduced ENF susceptibility (a sample with N42S +L44M + E137K). Prior to the availability of ENF, some men in the United States were infected with HIV that contained mutations associated with ENF resistance or hypersusceptibility. However, most of the mutations were not associated with phenotypic ENF resistance.
Accelerator Physics Measurements at the Damping Ring (1985)

Besides the optics measurements described elsewhere, machine experiments were done at the SLC damping ring to determine some of its parameters. The synchrotron radiation energy loss which gives the damping rates was measured by observing the RF-voltage dependence of the synchronous phase angle. The emittance was obtained from the synchrotron light monitor, scraper measurements and by extracting the beam through a doublet and measuring its size for different quadrupole settings. Current dependent effects such as parasitic mode losses, head tail instabilities, synchrotron and betatron frequency shifts were measured to estimate the impedance. RF-cavity beam loading and its compensation were also studied and ion collection was investigated. All results agree reasonably well with expectations and indicate no limitations to the design performance.
3D Face Recognition (2006)

In this paper, we compare face recognition performances of various features applied on registered 3D scans of faces. The features we compare are DFT or DCT-based features, ICA-based features and NNMF-based features. We apply the feature extraction techniques to three different representations of registered faces: 3D point clouds, 2D depth images and 3D voxel representations. We also consider block-based DFT or DCT-based local features on 2D depth images and their fusion schemes. Experiments using different combinations of representation types and feature vectors are conducted on the 3D-RMA dataset.
Polyatomic ions as internal standards for matrix corrections in inductively coupled plasma mass spectrometry (1995)

Several strong polyatomic ion signals common in inductively coupled plasma mass spectrometry can be used as internal standards to correct for matrix interferences. Signals for most of the polyatomic ions, including metal oxides, are suppressed by a Cs matrix to the same extent as analyte ion signals at nearby m/z values. Examples include 14N2+ and 24Mg+, 35Cl16O+ and 55Mn+, 40Ar16O+ and 59Co+, 32S16O+ and 45Sc+, 40Ar2+ and 75As+, and 89Y16O+ and 103Rh+. The count rates for these polyatomic ions are often measured anyway to determine interference corrections for spectral overlap, so these signals should reduce the number of added elements necessary to correct for matrix interferences.
Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition (2021)

Abstract Background We undertook longitudinal β-amyloid positron emission tomography (Aβ-PET) imaging as a translational tool for monitoring of chronic treatment with the peroxisome proliferator-activated receptor gamma (PPARγ) agonist pioglitazone in Aβ model mice. We thus tested the hypothesis this treatment would rescue from increases of the Aβ-PET signal while promoting spatial learning and preservation of synaptic density. Methods PS2APP mice (N=23; baseline age: 8 months) and App NL-G-F mice (N=37; baseline age: 5 months) were investigated longitudinally for five months using Aβ-PET. Groups of mice were treated with pioglitazone or vehicle during the follow-up interval. We tested spatial memory performance and confirmed terminal PET findings by immunohistochemical and biochemistry analyses. Results Surprisingly, Aβ-PET and immunohistochemistry revealed a shift towards higher fibrillary composition of Aβ-plaques during upon chronic pioglitazone treatment. Nonetheless, synaptic density and spatial learning were improved in transgenic mice with pioglitazone treatment, in association with the increased plaque fibrillarity. Conclusion These translational data suggest that a shift towards higher plaque fibrillarity protects cognitive function and brain integrity. Increases in the Aβ-PET signal upon immunomodulatory treatments targeting Aβ aggregation can thus be protective.
Stereotaxic laser ablation of intracranial lesions. (1983)

A technique is described which combines computed tomography-based stereotaxic localization and CO2 laser ablation of certain intracranial lesions with a high degree of accuracy. In 24 patients operated on with this technique, total ablation of the lesion was achieved in 19 and incomplete ablation in the other five. Though not perfect, this method is a new approach to intracranial lesions that promises to be more efficacious as future developments occur.
Novel Synthesis of the Ortho Ester Derivative of 4,5-Epoxymorphinan (2006)

[reaction: see text]. A method was found for the novel synthesis of ortho ester derivatives that are potentially useful as selective epsilon opioid receptor ligands. An unexpected 17-(cyclopropylmethyl)-4,5alpha-epoxy-6alpha-hydroxy-3,7,7-trimethoxy-8-oxa-6,14-endoethanomorphinan was produced when 17-(cyclopropylmethyl)-4,5alpha-epoxy-3-methoxy-6alpha,14-dihydroxy-6beta-(1,3-dithia-2-yl)-morphinan was treated in methanol with trimethyl orthoformate and CuO/CuCl2. This ortho ester derivative was then converted to an ester with acid. The structure of the ortho ester was determined by 2D NMR (HMBC) and mass spectra.
Synthesis, Characterization, and Catalytic Activities of Palladium Complexes with Phenylene-Bridged Bis(thione) Ligands (2019)

The neutral phenylene-bridged bis(thione) compounds, 1,3-bis(3′-ethylimidazolyl-2′-thione)benzene (Betb), 1,3-bis(3′-butylimidazolyl-2′-thione)benzene (Bbtb), and 1,3-bis(3′-allylimidazolyl-2′-thione)benzene (Batb), have been synthesized and characterized. Reactions of palladium precursor PdCl2(CH3CN)2 with phenylene-bridged bis(thione) ligands in 1:2 ratio resulted in the formation of the complexes: PdCl2(L)2 (L = Betb, 3a; L = Bbtb, 3b; L = Batb, 3c, respectively). In contrast, treatment of the ligands with PdCl2(CH3CN)2 in 1:1 ratio gave cyclometalation palladium complexes Pd2+Cl(L–) (L = Betb-H, 4a; L = Bbtb-H, 4b; L = Batb-H, 4c) through the metal-induced C–H activation. Complexes 4a–c can also be obtained by the reaction of bis(thione) ligands and PdCl2 in 1:1 ratio. The reaction of 3a–c with additional PdCl2(CH3CN)2 also afforded complexes 4a–c. All ligands and palladium complexes were fully characterized by one-/two-dimensional NMR spectra, mass spectrometry, and infrared spectrometry. And the molecular structures of 3a–c, 4a, and 4c have been determined by the single-crystal X-ray diffraction method. Furthermore, the detailed spectroscopic properties and catalytic activities of the complexes for the reduction of nitro compounds were discussed in terms of the modification of the coordination ligands to the center metal.
Development of vibrotactile measurement techniques for assessing mechanoreceptor performance at the fingertip (1986)

In recent years knowledge of the basic physiology of mechanoreceptors has advanced considerably. The translation of this knowledge into psychophysical threshold measurement techniques for assessing mechanoreceptor performance at the fingertip will be described. The sensitivity of three types of mechanoreceptors, the Pacinian corpuscles, Meissner corpuscles, and Merkel disks, is obtained from threshold measurements with sinusoidal vibratory stimuli at various frequencies across the band from 2–400 Hz. Parameters affecting the coupling of the vibrating probe to the finger, namely, static force, skin indentation, and probe diameter, have a significant and different effect on the thresholds for the different receptors. The role of background vibration of physiological origin (physiological noise) on the perception thresholds will be discussed.
Growing Depth Image Superpixels for Foliage Modeling (2016)

This paper presents a method for segmenting depth images into superpixels without requiring color images. Typically superpixel methods cluster pixels based on proximity in a multidimensional color space. However, building superpixels from time-of-flight depth images poses a number of new challenges including: pixels do not have color channels for similarity comparisons, the resolution of depth cameras is low compared to color, and there is significant depth noise. To address these we propose a superpixel method that approximates a depth image with set of planar facets. Facets are grown from seed points to cover the scene. Facet boundaries tend to coincide with high curvature regions and depth discontinuities, typically giving an over-segmentation of the scene. This work is motivated by automated foliage modeling, and the data we consider are of dense 3D foliage. Superpixel results are shown on foliage and are quantified using labeled data.
E. coli RNase III(E38A) generates discrete-sized products from long dsRNA (2009)

Ribonuclease III (RNase III) represents a highly conserved family of double-strand-specific endoribonucleases that are important for RNA processing and post-transcriptional gene regulation in both prokaryotes and eukaryotes. We constructed a single amino acid substitution (E38A) of RNase III that shows a unique and useful enzymatic activity. It produces a dsRNA product of a discrete size migrating as 23 base pairs (bp) when given a long dsRNA as a substrate in an easy-to-control reaction. We demonstrate that the RNase III(E38A) mutant produces the 23-bp dsRNA product by making a double-strand cleavage of the long dsRNA substrate with the product being protected from further digestion. Using the hairpin RNA R1.1 as a substrate, RNase III(E38A) cleaves at the primary site and remains bound to the RNA, thereby preventing cleavage at the secondary site. The 23-bp dsRNA product is demonstrated to be a pool of dsRNAs representative of the long dsRNA substrate and has RNA interference activity in mammalian tissue culture transfection experiments. The RNA interference activity suggests that the 23-bp dsRNA product has typical 2-nucleotide 3' overhangs and behaves as siRNA thereby making it a useful tool in RNA interference experiments.
More children benefiting from improved cochlear implant technology (2004)

![Figure][1] 

Dr. Papsin



Have you heard about the latest advances in pediatric cochlear implantation? Your patients with implants have.

Cochlear implants have become a successful method of habilitating children with severe to profound sensorineural hearing loss. In well selected children,
User Authentication with Smart Cards in Trusted Computing Architecture. (2004)

The introduction of smart cards into trusted architectures establishes a clear-cut separation between the roles and responsibilities of both platform and user. On one hand, the Trusted Platform Module (TPM) ensures the platform trustworthiness and secures platform credentials and secrets, while smart cards guarantee user identity and protect user credentials and access authorization.
[Acute ischemia of the anterior segment in Horton's disease]. (1978)

Due to their unique steric and electronic properties, air-stability and modular structure, chiral hybrid P,N-ferrocenyl ligands play a prominent role in the field of asymmetric catalysis. This report aims to give a concise introduction to the syntheses of chiral hybrid P,N-ferrocenyl ligands and presents an overview of their application in enantioselective catalysis. This review is of special interest for chemists working on ligand design and asymmetric catalysis, as well as for the broader organic and inorganic community.\nKeywords : ferrocene; nantioselective catalysis; P,N ligands
Operation and Supervision Control in Smart Transformer-based Meshed and Hybrid Grids (2020)

Solid-state transformer-based smart transformer (ST) can operate in meshed and hybrid grids, which can increase the hosting capacity of renewables and meanwhile reduce the reinforcements in electric grids. In order to adapt the new paradigm, the system performances of the ST-based meshed and hybrid grids are studied and then an effective energy management system (EMS), which is based on a distributed control architecture, is presented to control the meshed and hybrid grids operating in an intelligent and coordinated way.
Symptomatic Improvement Associated With Combined Estramustine and Vinblastine Chemotherapy for Metastatic Prostate Cancer (1996)

We evaluated the effectiveness of combination chemotherapy using estramustine and velban for metastatic prostate cancer. Patients with progressive metasatatic prostate cancer and rising prostate-specific antigen (PSA) values were evaluated between 1992 and 1994. All treatment was given on an outpatient basis. Vinblastine, 4 mg/m2 i.v., was given weekly for 6 weeks with a 2-week rest period. Estramustine, 10 mg/kg orally, was given in three divided doses for 6 weeks with a 2-week rest period between cycles. Of 15 patients, six (40%) had a response, in which a 25% decrease in PSA was associated with subjective improvement. There were no complete responses. Five partial responders had less pain. Median duration of response or time to progression was 9 months. Survival was 11.7 months for responders, 13.2 months for nonresponders. The combination of estramustine and velban is an effective therapy in progressive metastatic prostate cancer as measured by a decrease in PSA and improvement of symptoms.
Conductivity via Thermally Induced Gap States in a Polyoxometalate Thin Layer (2019)

We report a study of α-[P2W18O62]6–, Wells–Dawson polyoxometalate (POM) layers deposited on indium tin oxide (ITO)-coated glass substrates. A variety of techniques have been used including atomic force microscopy for surface topography characterization, current mapping, and current–voltage characteristics, X-ray photoemission spectroscopy for chemical analysis, UV–visible photoemission spectroscopy for determination of band line-ups, and energy dispersive X-ray reflectivity for determination of layer thicknesses and scattering length densities. The conditions of film deposition and subsequent thermal annealing strongly affect the film characteristics. In particular, we show that nanostriped films a few tens of nm thick can be obtained in a reproducible manner and that such structuring is accompanied by the appearance of gap states and by a switch from an insulating to a conductive state. Current–voltage characteristics demonstrate that highly ordered films of K6[P2W18O62] allow electron flow only from ITO to [P2W18O62]6–, thus showing a rectifying effect. Finally, we integrate the POM layer into an organic photovoltaic device and show the conduction through it thanks to favorable band alignment between ITO, the gap states, and the active photovoltaic layers.
Achieving Simplified Biasing Conditions with Pin Reduction Approach to enhance Static Fault Localization Capability (2018)

Successful fault localization is heavily dependent on the ability to replicate the failure mode in the analytical scanning optical microscope (SOM) system for defect isolation. However, typical SOM configuration with confined stage space is limited to about 4 probes - 4 SMUs resources for bench measurement. This has impeded the successful debug of functional IDDQ/powerdown leakage failure which may require higher pin counts to enter into leakage mode. In this paper, the static fault localization capability of such failures is enhanced with an engineering approach to simplify the biasing conditions for static debug within the SOM system with limited test resources. This is especially useful in a foundry environment that manufactures a wide variety of products from differentiated process lines. Several case studies were described to demonstrate how this optimized electrical FA flow was applied with great success to debug multiple challenging low yield functional leakage issues.