gebhart/patrepeval huggingface dataset:
An analytical evaluation of top-down versus bottom-up forecast in the electricity demand (2016)

Demand and supply balancing is the key technology for power management and high-efficiency planning. As the smart metering device is getting popular in the Japan, USA and EU, the more data from smart meter can be collected for the better forecast. Forecast based on the Top-Down versus Bottom-Up was a long-term discussion for various fields. We performed a short-term power demand curve forecast based on Gradient boosting machine to compare the two methods. We found that there is very slight advantage of the bottom-up method in the demand forecast just based on the demand data.
Large Bore 'HPHT' WeWieads and Christmas Trees (1999)

Abstract As "Large Bore" and "HPHT" (High Pressure/High Tempemture) type completions are becoming a more common occurrence around the world, operators such as Shell are going a step further and are requiring a combination of both technologies thus creating new challenges for the industry. The use of 'Large Bore' and "HPHT" type completion equipment can reduce the number of wells drilled, depending on field architecture, which has significant cost savings for the operator considering the cost of "HPHT" well construction. One project which is using Large Bore "HPHT'"equipment is Shearwater, which is located in the Central Graben Area of the North Sea and operated by Shell UK Exploration and Production. The wells for this project are being completed with 6.3/8" bore 15,000 psi 350°F Christmas Trees with full metal to metal sealing wellheads. This paper will review the challenges that were experienced during the design phase which included, but not limited to, operational issues, such as manual versus remote valve actuation, tree configuration, qualification testing requirements, API scaling rules, thermal analysis and material selection of qualification test equipment. This paper will also review the use of this technology for subsea applications, which is another milestone for both "HPHT" and subsea wells. Introduction In late 1996 Cameron began working with Shell on the Shearwater Development Project. Shearwater is iocated in Ccntrat Graben Area of the North Sea east of Aberdeen (Fig. 1). This project required the development of a large bore high pressure/high temperature christmas tree and wellhead/tubing hanger system to integrate with the 7" × 5.1/2" completion philosophy. The use of field proven technology was of the utmost importance to reduce the risk to both parties, taking into consideration the project was underway and only a limited amount of time was available for development work and qualification testing. The use of large bore completions can reduce the total number of wells required to complete a field. For example, on Shearwater the use of 7" completions eliminated three wells. Considering one "HPHT" well may take several months to drill and complete, there are significant cost savings, especially taking the current rig rates into consideration. The majority of the development effort was centered around the christmas tree and the tubing hanger system. The wellhead required only minor design modifications as 13.5/8" 15,000 psi metal sealing wellheads have been in use for several years. The wellhend selected was a field proven two stack 21.1/4" 5000 psi × 13.5/8" 15,000 psi full metal to metal sealing, split compact type used in conjunction with a mudline casing support and adjustable surface hanger system. The tubing hanger for this wellhead, however was only designed for 4.1/2" completions, therefore required further development for a large bore completion. The casing program for these wells is 30" × 20" × 14" × 10.3/4" × 7" tubing.
Dengue Prevention and 35 Years of Vector Control in Singapore (2006)

10.3201/eid1206.051210
Crystal structure of tin tetrabromodioxane, SnBr4 · (C4H8O2), a one dimensional polymer of Sn(IV) (2002)

Article Crystal structure of tin tetrabromodioxane, SnBr4 · (C4H8O2), a one dimensional polymer of Sn(IV) was published on December 1, 2002 in the journal Zeitschrift für Kristallographie - New Crystal Structures (volume 217, issue 1).
Case report: Benign liver tumor with central necrosis (1978)

A 38 year old previously well woman had sudden onset of upper abdominal pain and fever. Ultrasound examination revealed a necrotizing lesion in the liver. Arteriography revealed findings consistent with an adenoma or focal nodular hyperplasia. A right lobectomy and wedge resection of a similar lesion in the left lobe were done. Microscopy of both lesions indicated focal nodular hyperplasia. Adenoma is said to be related to the contraceptive oral hormone; focal nodular hyperplasia not. But it is possible that both may have an increased incidence of bleeding in the users of the oral contraceptive hormones.
Artificial magnetism and modes at millimeter waves in 3D lattices of titanium oxide microspheres (2011)

We show a study of complex modes and the artificial magnetic properties at millimeter waves of 3D-periodic arrays of microspheres made of high permittivity materials, specifically titanium oxide, embedded in a homogeneous background. Each microsphere is modeled as a single magnetic dipole and complex modes in the 3D lattice are computed by means of the 3D-periodic dispersion relation including mutual interactions. The effective permeability and the effective refractive index versus frequency obtained by the modal analysis are shown and compared to those obtained with Maxwell Garnett homogenization theory and also to those retrieved by scattering parameters of finite thickness structures obtained through HFSS simulations by using the Nicolson-Ross-Weir method.
Adaptive Control of Dorsal Raphe by 5-HT4 in the Prefrontal Cortex Prevents Persistent Hypophagia following Stress (2017)

Transient reduced food intake (hypophagia) following high stress could have beneficial effects on longevity, but paradoxically, hypophagia can persist and become anorexia-like behavior. The neural underpinnings of stress-induced hypophagia and the mechanisms by which the brain prevents the transition from transient to persistent hypophagia remain undetermined. In this study, we report the involvement of a network governing goal-directed behavior (decision). This network consists of the ascending serotonergic inputs from the dorsal raphe nucleus (DR) to the medial prefrontal cortex (mPFC). Specifically, adult restoration of serotonin 4 receptor (5-HT<sub>4</sub>R) expression in the mPFC rescues hypophagia and specific molecular changes related to depression resistance in the DR (5-HT release elevation, 5-HT<sub>1A</sub> receptor, and 5-HT transporter reductions) of stressed 5-HT<sub>4</sub>R knockout mice. The adult mPFC-5-HT<sub>4</sub>R knockdown mimics the null phenotypes. When mPFC-5-HT<sub>4</sub>Rs are overexpressed and DR-5-HT1ARs are blocked in the DR, hypophagia following stress persists, suggesting an antidepressant action of early anorexia.
Circuits simulation of switch devices furnished with gain cell combined to FeRAM (2001)

Abstract This paper has described a new concept on programmable switch device furnished with gain cell combined to FeRAM. Compared with memories but ferroelectric memories under many aspects, they have even been favorably labeled the ideal memory because of their non-volatility, ease of programming and operation by low voltage. As the programming switch, which is very attractive for logic application, SRAM, anti-fuse, flash type devices are well known. They have been required that satisfy non-volatility and low-voltage programming simultaneously. Some structures with ferroelectric material have been proposed and studied as solution of these problems. However, it seemed hard that these type devices are realized now from a viewpoint of fabrication process and low voltage operation. Therefore, we propose a new switch device furnished with gain cell combined to FeRAM. We have studied and simulated this switch device by SPICE. This basic circuit is composed of two blocks. One is switching block that includes gain cell, and the other is memory block that is FeRAM. Circuits, which we designed, amplify bit line's voltage up to Vdd or ground at sense amplification according to FeRAM data. The bit line voltage determines the logic state for gate electrode of switch transistor. The way to read is destructive read out. However, we can transfer information of bit line voltage during plate line is low-level voltage. The way to write FeRAM is similar to conventional way. It is revealed that the basic circuit with FeRAM connected gain cell could work correctly in simulation. In addition, this kind of device is hopeful of many logic applications.
Cellular and Molecular Aspects of Monoamine Neurotransmitter Transporters (1996)

Neurotransmitter transporters terminate synaptic neurotransmission by accumulating neurotransmitters once again after release in a sodium- and chloride-dependent fashion. The availability of the cloned neurotransmitter transporters has allowed investigation into the roles of these transporters in neuronal function. Molecular biological and protein engineering studies including in vitro site-directed mutagenesis, chimera formation of several transporter clones, or epitope-tagging various regions of transporter proteins, have revealed the topology and functionally mapped the transporter proteins. Monoamine neurotransmitter transporters such as those for dopamine, norepinephrine and serotonin are of interest, since they are a target of drugs of abuse and are involved in neuronal disorders including Parkinson's disease and depression. Therefore, elucidating the molecular basis of these transporters may clarify these problems and help develop treatments with which to combat these disorders and drug abuse.
Fluid dynamics characterization of a pneumatic bed using a spouted bed type solid feeding system (1992)

Abstract The development of a bed is reported, in which characteristics from spouted beds and pneumatic conveying are combined. The apparatus can be described as a pneumatic transport bed modified by the introduction of a recirculation process for inert materials, which leads to a final configuration akin to that of spouted beds. The dependency of the particle recirculation rates on the air flow rates and on the distance between the air inlet and the lower end of the central tube (z 0 ) was investigated. Also studied was the variation of the total pressure drop with air flow rate, for different loads of inert materials (glass spheres, d p = 2.8 mm) and different z 0 values.
Nissen Fundoplication for Gastroesophageal Reflux Disease (1986)

One hundred consecutive patients had a primary Nissen fundoplication for gastroesophageal reflux disease. None of the patients had previous gastric or esophageal surgery or evidence of esophageal stricture or motility disorder. The primary symptom was persistent heartburn in 89 patients and aspiration in 11. An abnormal pattern of esophageal acid exposure was documented in all patients with 24-hour esophageal pH monitoring. By actuarial analysis, the operation was 91% effective in the control of reflux symptoms over a 10-year period. The incidence of postoperative symptomatic gas bloat and increased flatus was lower in patients with preoperative abnormal manometric measurements of the distal esophageal sphincter (p less than 0.05). Three modifications in operative technique were made during the course of the study to minimize the side effects of the operation. First, enlarging the caliber of the bougie to size the fundoplication reduced the incidence of temporary swallowing discomfort from 83 to 39% (p less than 0.01). Second, shortening the length of the fundoplication decreased the incidence of persistent dysphagia from 21 to 3% (p less than 0.01). Third, mobilizing the gastric fundus for construction of the fundoplication increased the incidence of complete distal esophageal sphincter relaxation on swallowing from 31 to 71% (p less than 0.05). This was done to prevent the delayed esophageal acid clearance secondary to incomplete sphincter relaxation observed after operation in five of 36 studied patients. It is concluded that by proper patient selection and the incorporation of the above surgical techniques, the Nissen fundoplication can re-establish a competent cardia and provide relief of reflux symptoms with minimal side effects.
Genetic Diversity of Porcine Circovirus Types 2 and 3 in Wild Boar in Italy (2022)

Porcine circovirus (PCV) infection is associated with relevant economic impact to the pig industry. To date, four species of PCV (PCV1 to 4) have been identified but only PCV2 has been associated firmly with disease in pigs. The objective of this study was to assess the prevalence of PCV2 and PCV3 in the wild boar population in Basilicata region, Southern Italy, since this region is characterized by large forested and rural areas and the anthropic pressure is lower than in other Italian regions. Liver samples from 82 hunted wild boar were collected in 2021 from 3 different hunting districts. Sixty (73%, 95%CI: 63-82) samples tested positive for PCVs by quantitative PCR. In detail, 22 (27%, 95%CI: 18-37) were positive for PCV2, 58 (71%, 95%CI: 60-79) for PCV3, and 20 (24.4%, 95%CI 16-35) for both PCV2 and PCV3. On genome sequencing, different types and sub-types of PCV2 and PCV3 were identified, remarking a genetic diversity and hinting to a global circulation for the identified PCV strains. Overall, the high prevalence suggests that PCV2 and PCV3 infections are endemic in the wild boar population, posing risks for semi-intensive and free-range pig farming, typical of this region, due to contact with PCV-infected wild boar.
Approach to the Blues: A Highly Flexible Route to the Azulenes (2005)

Palette von Blau: Chlorbicyclo[5.3.0]decatrienone sind einfach aus Cycloheptatrienen zugänglich: Cycloaddition von Dichlorketen, Ringerweiterung mit einem Diazoalkan und Dehydrochlorierung in Dimethylformamid. Diese Verbindungen dienen als Zwischenstufen in der regiokontrollierten Synthese einer Vielzahl natürlicher und nichtnatürlicher Azulene (siehe Schema).
Antidepressant Combinations: Widely Used, but Far from Empirically Validated (2011)

This paper reviews the evidence on combining antidepressants (ADs) for treatment of major depressive disorder. Although widely used and usually safe, the efficacy of even the most widely prescribed combinations of ADs has not been established by properly controlled, adequately powered, clinical trials. This stands in contrast to several adjunctive strategies for AD nonresponders, including adjunctive lithium, thyroid hormone, or newer-generation antipsychotics. The wide use of AD combinations no doubt reflects the limited efficacy of commonly used ADs and the unmet need for effective strategies for patients with treatment-resistant depression. Although of unproven efficacy, potential merits of combining selected ADs include: (1) avoiding discontinuation-emergent symptoms and cross-titration schedules, (2) at worst, the second AD should be as effective in combination as it would be as a monotherapy following a switch, and (3) the possibility of complementary neuropharmacologic effects that may enhance efficacy or improve tolerability. The dearth of controlled studies of such a commonly used strategy for such a highly prevalent condition is symptomatic of shortcomings in the way clinically relevant research is funded, points to the need for industry-academic-federal collaborations, and underscores the need for large, practice-based, research groups that can efficiently complete publicly funded studies of high public health impact.
In Vitro Propagation of Alnus glutinosa Gaertn1 (1981)

Abstract Rapid clonal propagation of Alnus glutinosa was achieved in vitro using lateral buds excised from greenhouse grown, juvenile stock plants. Multiple shoot development occurred in 50% of the cultures after the first subculture (7–8 weeks after initial explanting) using a low salt, woody plant medium containing 1 μM 6-benzylaminopurine (BA). Microshoots were removed from pro-liferating tissues and rooted in a conventional potting medium under high humidity prior to establishment in the greenhouse.
COCOA: Cold Start Aware Capacity Planning for Function-as-a-Service Platforms (2020)

Function-as-a-Service (FaaS) is increasingly popular in the software industry due to the implied cost-savings in event-driven workloads and its synergy with DevOps. To size an on-premise FaaS platform, it is important to estimate the required CPU and memory capacity to serve the expected loads. Given the service-level agreements, it is however challenging to take the cold start issue into account during the sizing process. We have investigated the similarity of this problem with the hit rate improvement problem in TTL caches and concluded that solutions for TTL cache, although potentially applicable, lead to over-provisioning in FaaS. Thus, we propose a novel approach, COCOA, to solve this issue. COCOA uses a queueing-based approach to assess the effect of cold starts on FaaS response times. It also considers different memory consumption values depending on whether the function is idle or in execution. Using an event-driven FaaS simulator, FaasSim, we have developed, we show that COCOA can reduce over-provisioning by over 70% in some workloads, while satisfying the service-level agreements.
Does Working from Home Work? Evidence from a Chinese Experiment* (2014)

Abstract A rising share of employees now regularly engage in working from home (WFH), but there are concerns this can lead to “shirking from home.” We report the results of a WFH experiment at Ctrip, a 16,000-employee, NASDAQ-listed Chinese travel agency. Call center employees who volunteered to WFH were randomly assigned either to work from home or in the office for nine months. Home working led to a 13% performance increase, of which 9% was from working more minutes per shift (fewer breaks and sick days) and 4% from more calls per minute (attributed to a quieter and more convenient working environment). Home workers also reported improved work satisfaction, and their attrition rate halved, but their promotion rate conditional on performance fell. Due to the success of the experiment, Ctrip rolled out the option to WFH to the whole firm and allowed the experimental employees to reselect between the home and office. Interestingly, over half of them switched, which led to the gains from WFH almost doubling to 22%. This highlights the benefits of learning and selection effects when adopting modern management practices like WFH.
The Efficacy of Stroke Rehabilitation: A Qualitative Review (2003)

A systematic review of randomized controlled trials published from 1970-2002 was conducted to assess whether specialized inpatient stroke rehabilitation is associated with improved outcomes compared to conventional care. Twelve studies involving 2,813 patients were included for detailed review. The methodological quality of the studies was assessed using the PEDro Scale. The outcomes of death, functional outcome, length of hospital stay, and rates of institutionalization were compared between the intervention and control group(s). Improved functional outcomes and reduced length of hospital stays were reported among patients receiving specialized rehabilitation in the majority of studies (7/12 and 5/8, respectively), while no differences in mortality or institutionalization were reported between the groups.
Hybrid energy storage module for large-scale ship pulsed power (2017)

This discusses rotating machinery and system options for large scale Hybrid Energy Storage Modules (HESM) which are applicable to several naval ship platforms. The technology encompasses both medium voltage AC and medium voltage DC ship distribution systems up to 20 kVDC with equal emphasis. The basic configuration uses a combination of high-density battery storage combined with high speed compact rotating machinery/inertial storage to serve a wide range of pulsed power loads ranging from 600 kW to 30 MW. One example configuration is shown for a surface combatant with a MVAC power distribution whereby HESM also supports the radar system.
Inhibition of Various Immunological Reactions in vivo by a New Synthetic Complement Inhibitor (1982)

FUT-175 (6 amidino-2-naphthyl-4-guanidino benzoate-dimethanesulfonate), a new synthetic protease inhibitor, inhibits the enzyme activities of various proteases, such as Clr, C1 esterase, thrombin, kallikrein, plasmin and trypsin. FUT-175 strongly inhibited complement-medicated hemolysis via the classical and alternative pathways. The effects of FUT-175 on various immunological reactions in vivo were studied. The minimal effective dose of FUT-175 in systemic Forssman shock in guinea pigs was 6.25 mg/kg i.p. and 25 mg/kg p.o. In passive Arthus reactions in rats, the effective dose was 25 mg/kg i.p. and 250 mg/kg p.o. FUT-175 also inhibited other immunological reactions, such as passive cutaneous anaphylaxis and delayed hypersensitivity. Furthermore, at a dose of 25 mg/kg i.p. it strongly protected mice from death in endotoxin shock.
Triazolo[4,5-d]pyrimidines. VI. 3-Phenyl-3H-1,2,3-triazolo[4,5-d]-pyrimidine-7-carbonitrile and related compounds. (1980)

Nucleophilic reagents were found to react with 3-phenyl-3H-1, 2, 3-triazolo [4, 5-d]-pyrimidine-7-carbonitrile (1) in two ways, depending on the nature of the reagent. One is substitution by attack of the reagent of the carbon at the 7-position, to which the cyano group is bonded. The other is addition to the cyano group by attack of the reagent at the carbon of the cyano group. The substitution reaction occurs with amines, alkoxide ions, carbanions (active methylene compounds or ketones in the presence of sodium hydride), and the Grignard reagents, resulting in the formation of 4-alkylamino-(2), 4-alkoxy-(3), 4-substituted (4), and 4-alkyl-3-phenyl-3H-1, 2, 3-triazolo [4, 5-d] pyrimidines (5), respectively. The addition reaction occurs in the reactions with 98% sulfuric acid and with hydroxylamine, resulting in the formation of amide (6a) and amidoxime (7), respectively. The amide (6a) forms esters (8) with alcohols, in the presence of acid. The ethyl ester (8b) is hydrolyzed by ethanolic potassium hydroxide to give the acid (9). Moreover, 8b reacts with amines, hydroxylamine, and hydrazines to form amides (6b and 6c), hydroxamic acid (10), and hydrazides (11a and 11b), respectively.
A new cuticle scale hydrolysing protease from Beauveria brongniartii (2006)

From a screening for the production of new proteases specific for cuticle scales, Beauveria brongniartii was selected producing an alkaline Ca(++) dependent protease. The purified had a molecular weight of 27 kDa and a pI value of 8.0. Substrate specificities of model substrates (wool with partially removed cuticles treated with SDS) were analyzed by protein release, dissolved organic carbon (DOC) and nitrogen analysis. The C/N ratio of released material turned out to be a good parameter to determine the site of action of proteases on fibres. Compared to other enzymes, the fungal protease preferentially hydrolyzed cuticle scales and has thus a potential for anti-shrinking pre-treatment of wool fabrics.