gebhart/patrepeval huggingface dataset:
Wave fields in three dimensions: analysis and synthesis (1996)

Distributions of wave fields in three-dimensional domains are analyzed, synthesized, and generated experimentally. Fundamental limits are discussed and sampling conditions are derived for their generation, with use of a single diffractive element. A general design procedure, based on optimization algorithms, is developed and implemented. Experimental results show that special three-dimensional light distributions can be achieved with low-information-content elements in on-axis configurations.
Translating Comparative TJR Outcomes for Performance Improvement to Guide Surgical Quality Improvement (2020)

Background/Purpose: With the CMS decision to publicly report hospital-specific post-operative total joint replacement (TJR) complications and readmissions, orthopedic surgeons need new sources of post-operative outcome data to monitor and improve post-hospital care. The AHRQ funded research program, Function and Outcomes Research for Comparative Effectiveness in Total Joint Replacement (FORCE-TJR), developed methods to capture longitudinal patient-reported outcomes (PROs) and comprehensive post-TJR medical and surgical events, and established a web reporting system to return comparative outcome reports to participating surgeons and hospitals in order to monitor and improve quality and outcomes. Methods: This national cohort/registry captures post-TJR measures directly from patients in their homes to assure uniform time, completion, and consistency for data comparisons across hospitals. Quarterly updated web reports deliver hospital- and surgeon-specific TJR outcomes compared with those of their peers and risk-adjusted national benchmarks on PROs as well as on post-operative event rates. Results: Our national cohort enrolled 25,000 patients from 150 diverse orthopedists in 22 US states with varied hospital and surgeon practices. The secure, HIPAA compliant website was established that presents summary and risk-adjusted comparative statistics for primary TJR for all enrolled patients. The website provides a downloadable and printable report and an Executive Summary of key pre-operative patient risk factors, post-operative events, and post-operative PROs enabling the providers to compare their outcomes to the other participating sites. Individual patient reports are available for surgeons with real-time scores and trended outcome data to facilitate patient and surgeon shared treatment decision making. Conclusion/Implications: A secure reporting website was established to disseminate comparative outcome reports to all participating hospitals and surgeons. Returning comparative outcome data to hospitals and surgeons encourages their active participation in this national registry and allows them to undstand their relative performance compared to peers while supporting practice-level quality monitoring and improvement efforts in patient care.
<title>Issues in performance modeling of data teletraffic</title> (1997)

Data teletraffic is characterized by bursty arrival processes. Performance models are characterized by a desire to know under what circumstances is the probability that an arrival finds a full input buffer very small. In this paper I examine how four models proposed in the literature perform on two data sets of local-area-network traffic. Among my conclusions are (1) the protocol governing the data transmission may have a substantial effect on the statistical properties of the packet stream, (2) approximating the probability that a finite buffer of size b overflows may not be adequately approximated by the probability that an infinite buffer has at least b packets in it, and (3) a data-based estimate of large-deviation rate-function does the best job of estimating packet loss on these data sets. This method may overestimate the loss rate by several orders of magnitude, so there is room for further refinements.
[Peripheral pulmonary neoplasms: combined imaging (computerized tomography, ultrasonography, magnetic resonance) in the evaluation of chest wall involvement]. (1993)

Chest wall involvement by a peripheral lung neoplasm, found in 4-8% of the cases, makes a difference in both staging and surgical approach. In the evaluation of the regional extent of the tumor, the radiologist must give the surgeon as much information as possible about relationships between lung neoplasm and chest wall structures, to correctly evaluate stage-T2 cancers and differentiate them from stage-T3 cancers. The authors report the results of a study made to assess the value of Computed Tomography (CT), ultrasonography (US) and Magnetic Resonance Imaging (MRI) to define chest wall invasion by a peripheral bronchogenic carcinoma. To this purpose 25 patients with primary peripheral lung neoplasm were studied with CT, US and MRI and the results were compared with surgical findings by means of TNM classification. Overall sensitivity and specificity were 68% and 74% for CT, 74% and 72% for US and 88% and 86% for MRI, respectively. CT, which still plays the major role in staging lung cancer, seems to get the worst results because of its impossibility to differentiate the cancers adjoining the chest wall from those showing signs of initial invasion. In these cases the use of the other imaging techniques (US, MRI) depends on their availability and on the specific experience of the radiologist.
Alejandro Obregón: Obras maestras, 1941-1991. 1ª Parte: Alejandro Obregón: Medio siglo de genio (texto crítico) (1991)

Analisis critico de la produccion artistica de este pintor hispano-colombiano, mediante el estudio estilistico-formal y conceptual de los distintos temas desarrollados por el durante los cincuenta anos considerados.
Agallamh le Donnchadh O Luasaigh (Bailiúchán Béaloidis) (2011)

Leigheasanna Traidisiunta. Interview with Donnchadh O Luasaigh on the topic of traditional medicines.
Mimicking a Stenocara Beetle's Back for Microcondensation Using Plasmachemical Patterned Superhydrophobic−Superhydrophilic Surfaces (2006)

A simple two-step plasmachemical methodology is outlined for the fabrication of microcondensor surfaces. This comprises the creation of a superhydrophobic background followed by pulsed plasma deposition of a hydrophilic polymer array. Microcondensation efficiency has been explored in terms of the chemical nature of the hydrophilic pixels and their dimensions. These results are compared to the hydrophilic-hydrophobic pattern present on the Stenocara beetle's back, which is used by the insect to collect water in the desert. Potential applications include fog harvesting, microfluidics, and biomolecule immobilization.
Bandpass filter using TM-mode dielectric rod resonators with novel input coupling (2009)

In this paper, a bandpass filter is presented, which is based on TM-mode operation in dielectric rods. The bandpass filter consists of 7 resonators, has a center frequency of 1950 MHz, a bandwidth of 60 MHz and two cross-couplings by cascaded quadruplet configurations for improved blocking performance. The layout will be discussed. A novel input coupling assembly is introduced. Parametric study for the coupling performance is presented. Furthermore, measurement results are shown.
Structure–function analysis of the A20‐binding inhibitor of NF‐κB activation, ABIN‐1 (2003)

Nuclear factor kappa B (NF-kappa B)-dependent gene expression plays an important role in numerous cellular processes including stress responses, inflammation and cell proliferation. Therefore, the activity of this transcription factor needs to be tightly regulated. Among others, the NF-kappa B-dependent zinc finger protein A20 is involved in the negative feedback regulation of NF-kappa B activation in response to tumor necrosis factor (TNF). We previously demonstrated that A20 can interact with A20-binding inhibitors of NF-kappa B activation (ABINs), which have the potential to inhibit TNF-induced activation of NF-kappa B upon overexpression. The ABIN proteins were therefore proposed to mediate the NF-kappa B inhibiting function of A20. Here we demonstrate the presence of a short homologous region in ABINs and I kappa B kinase gamma, the regulatory subunit of the I kappa B kinase complex. Site-specific mutagenesis of this region abolished the NF-kappa B inhibiting function of ABIN-1, without affecting the interaction with A20. Furthermore, coexpression of these ABIN-1 mutants interfered in a dominant negative manner with the NF-kappa B inhibiting function of ABIN-1, whereas the A20-mediated inhibition was unaffected. These results suggest that A20 and ABIN-1 probably act independently of their mutual interaction.
The Relative Stabilities of cis and trans Isomers. IV. The 3,5-Dimethylcycloheptanones1,2 (1959)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Relative Stabilities of cis and trans Isomers. IV. The 3,5-Dimethylcycloheptanones1,2Norman L. AllingerCite this: J. Am. Chem. Soc. 1959, 81, 1, 232–236Publication Date (Print):January 1, 1959Publication History Published online1 May 2002Published inissue 1 January 1959https://pubs.acs.org/doi/10.1021/ja01510a053https://doi.org/10.1021/ja01510a053research-articleACS PublicationsRequest reuse permissionsArticle Views502Altmetric-Citations48LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Study of epoxy compounds. Part VI. Curing reactions of epoxy resin and acid anhydride with amine, acid, alcohol, and phenol as catalysts (1964)

Abstract The curing reaction of an epoxy resin and acid anhydride with an amine and/or acid, alcohol, and phenol was studied kinetically by using commercial epoxy resins and acid anhydrides. No etherification reaction occurred at 70–140°C., even in the case of epoxide/acid anhydride/HA (acid, alcohol, or phenol) and of epoxide/acid anhydride tertiary amine/HA, and the initial reaction rate was proportional to the concentrations of epoxide, acid anhydride, and catalysts such as tertiary amine, acid, alcohol, and phenol. The apparent activation energy of the reaction system of Epikote 828/methyl‐bicyclo(2,2,1)heptene‐2,3‐dicarboxylic anhydride/triethanol amine/HA was obtained as about 14.7 kcal./mole, and the low frequency factors and large negative entropies of activation for the reaction might confirm that the curing reaction of epoxy resins and anhydrides belongs to the type of nucleophilic bimolecular displacement reaction. The effects of the substituents, R, of acid, alcohol, and phenol as cocatalyst on the curing reaction of epoxy resin/acid anhydride/tertiary amine/HA were studied. The reaction constants, p , obtained positively for HA's, indicate that electron‐withdrawing substituents of HA increase the rate of curing reaction of system of epoxide/acid anhydride/amine/HA. Differences in the catalytic and cocatalytic effects among benzoic acid, benzyl alcohol, and phenol in these reaction systems might be considered to depend on the donating power of hydrogen bond which is the important role rather than a general electrostatic interaction effect as solvent effects in nucleophilic substitution reactions. These results supported the proposed mechanisms reasonably.
Pore Connectivity and Dewatering Mechanism of Tailings Bed in Raking Deep-Cone Thickener Process (2020)

Paste and thickened tailings (PTT) technology can improve the utilization and management of tailings from processing plants. The pore size distribution (PSD) and microstructure evolution affected by the rake shear in thickening tailings beds are essential to produce a high-density tailings underflow. Continuous thickening and computed tomography (CT) scanning tests were conducted to study the PSD with and without shear. The pore morphology was studied to reveal the shearing-dewatering performance of the tailings bed. The results show that at a flocculant solution concentration of 0.01 wt % and a feed slurry concentration of 10 wt%, the underflow concentration with and without shear can reach 58.5 wt %and 55.8 wt %, respectively. The CT image reconstruction models demonstrated that the porosity of the sheared tailings bed increased with the bed height. When the bed height increased from 2.5 to 10 cm, the porosity increased from 35.1% to 41.9%, the pore fractal dimension increased from the range 1.8–1.95 to the range 2.1–2.15, and the pore quantity decreased by 21.39%. The average pore volume increased with increasing height by 13.93%, 16.57% and 12.07%. The pore structure became more complex with the bed height, and the connectivity between pores increased to form water-flow channels, which were beneficial to the drainage of sealed water.
The Cross-Linking and Structure Modification of the Collagen Matrix in the Design of Cardiovascular Prosthesis (1988)

Glutaraldehyde cross-linking of native or reconstituted collagen fibrils and tissues rich in collagen significantly reduces biodegradation. Other aldehydes are less efficient than glutaraldehyde in generating chemically, biologically, and thermally stable cross-links. Implants of collagenous materials cross-linked with glutaraldehyde are subject long-term to calcification, biodegradation, and low-grade immune reactions. We have attempted to overcome these problems by enhancing cross-linking through (a) bridging of activated carboxyl groups with diamines and (b) using glutaraldehyde to cross-link the epsilon-NH2 groups in collagen and the unreacted amines introduced by aliphatic dismines. This cross-linking reduces tissue degradation and nearly eliminates humoral antibody induction. Covalent binding of diphosphonates, specifically 3-amino-1-hydroxypopane-1, 1-diphosphonic acid (3-APD), and to a lesser extent chondroitin sulfate to collagen or to the cross-ling-enhanced collagen network reduces its potential for calcification. Platelet aggregation also is reduced by glutaraldehyde cross-linking and nearly eliminated by the covalent binding of chondroitin sulfate to collagen. The cytotoxicity of residual glutaraldehyde can be minimized by chemical neutralization and thorough rough rinsing.
Arrangement of orthogonal polarized signals for suppressing fiber four-wave mixing in optical multichannel transmission systems (1991)

The arrangement of signal polarization states for suppressing fiber four-wave mixing (FWM) in optical multichannel transmission is described. Experiments show that light power generated through fiber FWM becomes 0 or 1/4 of the maximum value when signals are orthogonal. Based on the experimental results, power reduction of FWM light is evaluated for various arrangements of signal polarizations, and the optimum arrangements is shown to efficiently suppress fiber FWM in a multichannel system.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
The First Responder Network (FirstNet) and Next-Generation Communications for Public Safety: Issues for Congress (2017)

This report discusses the First Responder Network Authority (FirstNet), which is a federal agency that includes private sector and other non-federal representation on its board of directors. FirstNet was created by Congress with provisions in Title VI (Spectrum Act) of the Middle Class Tax Relief and Job Creation Act of 2012 (P.L. 112-96) to ensure the deployment and operation of a nationwide, broadband network for public safety communications.
A multi‐biomarker follow‐up study of patients with multiple sclerosis (2016)

The levels of all biomarkers changed concurrently with MS treatment. The sCD163 ratio was identified as a potential novel marker for time to DA.
Grasshopper-a persistent operating system for conventional hardware (2003)

The paper describes Grasshopper, an operating system designed to provide generic mechanisms capable of being tailored to support a wide range of persistence paradigms. A constraint placed on this design is that the system must be implementable on conventional architectures which support paged virtual memory. The basic system abstractions relating to addressing environments, processes, and protection are described. It is shown that these provide explicit support for distributed persistent objects and processes, stability, and access control. At the same time the system provides the flexibility to allow user implementation of alternative object management techniques.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Co-Localized or Randomly Distributed? Pair Cross Correlation of In Vivo Grown Subgingival Biofilm Bacteria Quantified by Digital Image Analysis (2012)

The polymicrobial nature of periodontal diseases is reflected by the diversity of phylotypes detected in subgingival plaque and the finding that consortia of suspected pathogens rather than single species are associated with disease development. A number of these microorganisms have been demonstrated in vitro to interact and enhance biofilm integration, survival or even pathogenic features. To examine the in vivo relevance of these proposed interactions, we extended the spatial arrangement analysis tool of the software daime (digital image analysis in microbial ecology). This modification enabled the quantitative analysis of microbial co-localization in images of subgingival biofilm species, where the biomass was confined to fractions of the whole-image area, a situation common for medical samples. Selected representatives of the disease-associated red and orange complexes that were previously suggested to interact with each other in vitro (Tannerella forsythia with Fusobacterium nucleatum and Porphyromonas gingivalis with Prevotella intermedia) were chosen for analysis and labeled with specific fluorescent probes via fluorescence in situ hybridization. Pair cross-correlation analysis of in vivo grown biofilms revealed tight clustering of F. nucleatum/periodonticum and T. forsythia at short distances (up to 6 µm) with a pronounced peak at 1.5 µm. While these results confirmed previous in vitro observations for F. nucleatum and T. forsythia, random spatial distribution was detected between P. gingivalis and P. intermedia in the in vivo samples. In conclusion, we successfully employed spatial arrangement analysis on the single cell level in clinically relevant medical samples and demonstrated the utility of this approach for the in vivo validation of in vitro observations by analyzing statistically relevant numbers of different patients. More importantly, the culture-independent nature of this approach enables similar quantitative analyses for "as-yet-uncultured" phylotypes which cannot be characterized in vitro.
Expression of Fibroblast Growth Factor 21 and β-Klotho Regulates Hepatic Fibrosis through the Nuclear Factor-κB and c-Jun N-Terminal Kinase Pathways (2018)

These results indicate that the inflammatory response during fibrogenesis increases FGF21 levels and suppresses β-Klotho via the NF-κB and JNK pathway. In addition, FGF21 likely protects hepatocytes from hepatic inflammation and fibrosis.
Stress-relaxation curves for the two sample geometries and bonding dependence on compression (2011)

<b>Copyright information:</b>Taken from "Bonding of articular cartilage using a combination of biochemical degradation and surface cross-linking"http://arthritis-research.com/content/9/3/R47Arthritis Research &amp; Therapy 2007;9(3):R47-R47.Published online 15 May 2007PMCID:PMC2206351. Stress-relaxation curves for the sample geometries G1 and G2 (see Figure 1e) were determined in a standardised creep modulus set-up. Samples were compressed by a stamp and the resulting force relaxation behaviour was analysed by recording the load over time. G1 (almost no compression) or G2 (compression) cartilage blocks were subjected to different cross-linkers (without degrading pre-treatment). Adhesive strength as a measure of bonding was determined immediately after cross-linking. Bars represent the mean with standard error of the mean of at least 16 samples derived from 4 independent experiments, each with at least 4 replicates per group. values in the graph are from pairwise comparisons using the Mann Whitney-U test. EDC, 1-ethyl-3-diaminopropyl-carbodiimide; NHS, N-hydroxysuccinimide.
Heterologous Expression of the Class IIa Bacteriocins, Plantaricin 423 and Mundticin ST4SA, in Escherichia coli Using Green Fluorescent Protein as a Fusion Partner (2020)

The antilisterial class IIa bacteriocins, plantaricin 423 and mundticin ST4SA, have previously been purified from the cell-free supernatants of <i>Lactobacillus plantarum</i> 423 and <i>Enterococcus mundtii</i> ST4SA, respectively. Here, we present the fusions of mature plantaricin 423 and mundticin ST4SA to His-tagged green fluorescent protein (GFP) for respective heterologous expression in <i>Escherichia coli</i>. Fusion of plantaricin 423 and mundticin ST4SA to His-tagged GFP produced the fusion proteins GFP-PlaX and GFP-MunX, respectively. Both fusion proteins were autofluorescent, circumvented inclusion body formation and lowered the toxicity of class IIa bacteriocins during heterologous expression. Not only did GFP-class IIa fusion stabilize heterologous expression and boost yields, the fluorescent intensity of GFP-PlaX and GFP-MunX could be monitored quantitatively and qualitatively throughout expression and purification. This robust fluorometric property allowed rapid optimization of conditions for expression and bacteriocin liberation from GFP via the incorporated WELQut protease cleavage sequence. Incubation temperature and IPTG concentration had a significant effect on bacteriocin yield, and was optimal at 18°C and 0.1-0.2 mM, respectively. GFP-MunX was approximately produced at a yield of 153.30 mg/L culture which resulted in 12.4 mg/L active mundticin ST4SA after liberation and HPLC purification. While GFP-PlaX was produced at a yield of 121.29 mg/L culture, evidence suggests heterologous expression resulted in conformation isomers of WELQut liberated plantaricin 423.