gebhart/patrepeval huggingface dataset:
Optimum design consideration and implementation of a parallel hybrid active power filter integrated into a three-phase capacitive diode rectifier (2011)

This paper describes the design and performance of a parallel hybrid active power filter integrated into a three-phase diode rectifier with a capacitive load. The hybrid filter is composed by a three-phase LC filter and a small rated active filter based on a three-phase voltage-source PWM converter. The passive filter is designed with focus on characteristic impedance, resonant frequency, influence on DC-bus voltage and filtering characteristics. In addition, a repetitive control algorithm with differential compensator is proposed to eliminate steady-state error in the control loop, and the design method is given in detail. The optimum design of circuit and control parameters including passive filter and repetitive controller allows the hybrid filter to minimize current THD drawn from the utility while minimizing the size and cost of the filter. The validity of the system design is confirmed by experimental results obtained from a 380 V, 20 kVA experimental prototype made in the Lab.
Multilateral Wells Improve Development in Heavy-Oil Field (2004)

This article, written by Technology Editor Dennis Denney, contains highlights of paper SPE 87207, "Multilateral/ Intelligent Wells Improve Development of Heavy-Oil Field: A Case History," by Pascal Rump, SPE, Baker Oil Tools, and Ronjoy Bairagi, John Fraser, SPE, and Klaus Mueller, SPE, Petroleum Development Oman, prepared for the 2004 IADC/SPE Drilling Conference, Dallas, 2-4 March.
Managing International Hospitality (1992)

The Spring 1992 issue of Hospitality Review featured Part I of this series on the impetus to internationalization of the hospitality industry, as well as the modes of overseas expansion by American firms. In Part 11, the author concludes with a look at the organization of overseas activities in their evolutionary stages and considers, as well, who some of the major international competitors to North American firms are in the international market and in North America. The article concludes with a brief consideration of opportunities for employment overseas.
Voltage Imaging of Epileptiform Activity in Slices From Rat Piriform Cortex: Onset and Propagation (1998)

The piriform cortex is a temporal lobe structure with a very high seizure susceptibility. To investigate the spatiotemporal characteristics of epileptiform activity, slices of piriform cortex were examined by imaging electrical activity with a voltage-sensitive fluorescent dye. Discharge activity was studied for different sites of stimulation and different planes of slicing along the anterior-posterior axis. Epileptiform behavior was elicited either by disinhibition with a gamma-aminobutyric acid-A receptor antagonist or by induction with a transient period of spontaneous bursting in low-chloride medium. Control activity recorded with fluorescent dye had the same pharmacological and temporal characteristics as control activity reported previously with microelectrodes. Simultaneous optical and extracellular microelectrode recordings of epileptiform discharges showed the same duration, latency, and all-or-none character as described previously with microelectrodes. Under all conditions examined, threshold electrical stimulation applied throughout the piriform cortex evoked all-or-none epileptiform discharges originating in a site that included the endopiriform nucleus, a previously identified site of discharge onset. In induced slices, but not disinhibited slices, the site of onset also included layer VI of the adjoining agranular insular cortex and perirhinal cortex, in slices from anterior and posterior piriform cortex, respectively. These locations had not been identified previously as sites of discharge onset. Thus like the endopiriform nucleus, the deep agranular insular cortex and perirhinal cortex have a very low seizure threshold. Additional subtle differences were noted between the induced and disinhibited models of epileptogenesis. Velocity was determined for discharges after onset, as they propagated outward to the overlying piriform cortex. Propagation in other directions was examined as well. In most cases, velocities were below that for action potential conduction, suggesting that recurrent excitation and/or ephaptic interactions play a role in discharge propagation. Future investigations of the cellular and organizational properties of regions identified in this study should help clarify the neurobiological basis of high seizure susceptibility.
Influence of Storage on Volatile Profiles in Roasted Almonds (Prunus dulcis) (2014)

Hexanal, peroxide value, and lipid hydroperoxides are common indicators of lipid oxidation in food products. However, these markers are not always reliable as levels are dynamic and often can be detected only after significant oxidation has occurred. Changes in the volatile composition of light- and dark-roast almonds were evaluated during storage over 24 weeks at 25 or 35 °C using headspace solid phase microextraction (HS-SPME) gas chromatography-mass spectrometry (GC-MS). Several volatile changes were identified in association with early oxidation events in roasted almonds. Hexenal decreased significantly during the first 6 weeks of storage and did not increase above initial levels until 20-24 weeks of storage depending upon the degree of roast. In contrast, levels of 1-heptanol and 1-octanol increased at 16-20 weeks, depending upon the degree of roast, and no initial losses were observed. Seventeen new compounds, absent in raw and freshly roasted almonds but detectable after 6 weeks of storage, were identified. Of these, 2-octanone, 2-nonanone, 3-octen-2-one, 2-decanone, (E)-2-decenal, 2,4-nonadienal, pentyl oxirane, and especially acetic acid increased significantly (that is, >10 ng/g). The degree of roasting did not correlate with the levels of these compounds. Significant decreases in roasting-related aroma volatiles such as 2-methylbutanal, 3-methylbutanal, furfural, 2-phenylacetaldehyde, 2,3-butanedione, 2-methylpyrazine, and 1-methylthio-2-propanol were observed by 4 weeks of storage independent of the degree of roast or storage conditions.
Micromechanical properties of keratin intermediate filament networks (2008)

Keratin intermediate filaments (KIFs) form cytoskeletal KIF networks that are essential for the structural integrity of epithelial cells. However, the mechanical properties of the in situ network have not been defined. Particle-tracking microrheology (PTM) was used to obtain the micromechanical properties of the KIF network in alveolar epithelial cells (AECs), independent of other cytoskeletal components, such as microtubules and microfilaments. The storage modulus (G') at 1 Hz of the KIF network decreases from the perinuclear region (335 dyn/cm(2)) to the cell periphery (95 dyn/cm(2)), yielding a mean value of 210 dyn/cm(2). These changes in G' are inversely proportional to the mesh size of the network, which increases approximately 10-fold from the perinuclear region (0.02 microm(2)) to the cell periphery (0.3 microm(2)). Shear stress (15 dyn/cm(2) for 4 h) applied across the surface of AECs induces a more uniform distribution of KIF, with the mesh size of the network ranging from 0.02 microm(2) near the nucleus to only 0.04 microm(2) at the cell periphery. This amounts to a 40% increase in the mean G'. The storage modulus of the KIF network in the perinuclear region accurately predicts the shear-induced deflection of the cell nucleus to be 0.87 +/- 0.03 microm. The high storage modulus of the KIF network, coupled with its solid-like rheological behavior, supports the role of KIF as an intracellular structural scaffold that helps epithelial cells to withstand external mechanical forces.
Efficacy of Cold‐Pressed Terpeneless Valencia Oil and Its Primary Components on Inhibition of  Listeria  Species by Direct Contact and Exposure to Vapors (2011)

This study used disk diffusion assays to evaluate the effectiveness of cold-pressed terpeneless Valencia oil (CPTVO) and its primary components (linalool, citral, and decanal) at inhibiting Listeria via direct contact or exposure to vapors. In general, all Listeria strains tested responded similarly to CPTVO and its components. Direct contact with linalool produced zones of inhibition that were significantly smaller (P < 0.0001) than those associated with all other antimicrobials tested. Zones of inhibition for sealed plates were significantly larger (P < 0.0001) than those observed for unsealed plates, although the method for sealing the plates was insignificant. Exposure to CPTVO vapors resulted in zones of inhibition that were significantly smaller than those resulting from decanal vapors (P < 0.0001). The difference observed between the zones of inhibition produced by antimicrobial exposure via vapors or direct contact was only slightly significant (P = 0.02). Antimicrobial essential oil (EO) vapors may be an effective alternative to direct contact EOs to safely and effectively inhibit microorganisms while minimizing undesired organoleptic changes sometimes associated with EO contact. CPTVO and its primary components, decanal and citral, may have potential in the food industry as all natural, generally recognized as safe antimicrobials used in modified atmosphere packaging designed to inhibit Listeria without requiring direct contact with food products.
Controlled Release from Bilayer-Decorated Magnetoliposomes via Electromagnetic Heating (2010)

Nanoscale assemblies that can be activated and controlled through external stimuli represent a next stage in multifunctional therapeutics. We report the formation, characterization, and release properties of bilayer-decorated magnetoliposomes (dMLs) that were prepared by embedding small hydrophobic SPIO nanoparticles at different lipid molecule to nanoparticle ratios within dipalmitoylphosphatidylcholine (DPPC) bilayers. The dML structure was examined by cryogenic transmission electron microscopy and differential scanning calorimetry, and release was examined by carboxyfluorescein leakage. Nanoparticle heating using alternating current electromagnetic fields (EMFs) operating at radio frequencies provided selective release of the encapsulated molecule at low nanoparticle concentrations and under physiologically acceptable EMF conditions. Without radio frequency heating, spontaneous leakage from the dMLs decreased with increasing nanoparticle loading, consistent with greater bilayer stability and a decrease in the effective dML surface area due to aggregation. With radio frequency heating, the initial rate and extent of leakage increased significantly as a function of nanoparticle loading and electromagnetic field strength. The mechanism of release is attributed to a combination of bilayer permeabilization and partial dML rupture.
T‐cell memory and recall responses to respiratory virus infections (2006)

The respiratory tract is characterized by its large surface area and the close association of an extensive vasculature with the external environment. As such, the respiratory tract is a major portal of entry for many pathogens. The immune system is able to effectively control most pulmonary pathogens and establish immunological memory that is capable of mediating an accelerated and enhanced recall response to secondary pathogen challenge. A key component of the recall response in the lung involves the rapid response of antigen-specific memory CD8+ T cells. Recent studies have shown that memory CD8+ T cells are extremely heterogeneous in terms of phenotype, function, anatomical distribution, and longevity. However, we have little understanding of how the different subsets of memory cells actually contribute to the recall response, especially with respect to peripheral or mucosal sites, such as the lung. Since immunological memory is the cornerstone of vaccination, it is essential that we understand how different memory CD8+ T-cell subsets are initially generated, maintained over time, and contribute to recall responses. This review focuses on memory T cells that mediate recall responses to influenza and parainfluenza virus infections in the lung.
A relative positioning system for co-located mobile devices (2005)

If a mobile computing device knows how it is positioned and oriented in relation to other devices nearby, then it can provide enhanced support for multi-device and multi-user interactions. Existing systems that provide position information to mobile computers are reliant on externally deployed infrastructure, such as beacons or sensors in the environment. We introduce the Relate system, which provides fine-grained relative position information to co-located devices on the basis of peer-to-peer sensing, thus overcoming dependence on any external infrastructure. The system is realised as a hardware/software plug-in, using ultrasound for peer-to-peer sensing, USB to interface with standard mobile devices, and data abstraction and inferencing to map sensor data to a spatial model that maintains both quantitative and qualitative relationships. We present a set of services and applications to demonstrate the utility of the system. We report experimental results on the accuracy of the relative position and orientation estimates, and other aspects of system performance.
Bandwidth-on-Demand Networks - a Solution to Peer-to-Peer (2003)

One of the most exciting aspects of the Internet is that it contains information about almost every imaginable subject. High-bandwidth availability with broadband net works is providing a powerful and popular means for the same situation to become true for video content. We describe here a vision where your broadband connection gives you access to an unimaginably vast library of almost every programme and film ever made.
Spatially Selective Electroless Deposition of Cobalt on Oxide Surfaces Directed by Microcontact Printing of Dendrimers (2002)

We describe a simple method for the fabrication of arbitrary submicrometer patterns of cobalt on a nonconducting surface with wet chemical methods and microcontact printing (μCP). A hydroxyl-terminated dendrimer is transferred from a stamp to the surface. The thickness of the dendrimer layer can be tuned by varying the concentration of the dendrimer ink solution. These dendrimer molecules act as host molecules. The guests, palladium ions, sorb into the layer and act as nucleation centers for electroless cobalt plating. We produced cobalt structures down to several hundred nanometers lateral size and up to several tens of nanometer thickness with high spatial selectivity. The printed dendrimers are cage-like molecules with well-defined chemical groups; hence, they can selectively bind guest molecules (here palladium complexes) when the latter possess chemical groups that favor a host−guest interaction. Printing dendrimers therefore points toward a more general method to create patterns with chemical functionality.
EW‐7197 prevents ulcerative colitis‐associated fibrosis and inflammation (2018)

EW-7197 is a transforming growth factor-β type I receptor kinase inhibitor with potential anti-inflammatory and antifibrotic properties. Here, we investigate the potential therapeutic effects of EW-7197 in a murine model of ulcerative colitis. EW-7197 attenuated the colitis disease activity index by improving rectal bleeding, body weight, and degree of stool consistency. EW-7197 also reduced colorectal tissue damage and the colon histopathological score by reducing crypt loss, mucosal damage, and tissue inflammation. Moreover, EW-7197 appeared to ameliorate the inflammatory and fibrotic responses by reducing oxidative stress, reducing submucosal edema and inflammatory cell infiltration, downregulating proinflammatory and pro-fibrotic genes, and inhibiting excessive collagen deposition in inflamed and fibrotic ulcerative colitis tissues. These results suggest that EW-7197 has potentially useful therapeutic properties against colitis, with clinically translational potential of inhibiting key pathological responses of inflammation and fibrosis in patients with colitis.
Cementing technique for total knee arthroplasty in cadavers using a pastry bone cement (2021)

The pastry cement facilitates the feasibility of cemented TKA. The pre-clinical tests indicate that the pastry bone cement fulfills the requirements for bone cement in the field of knee arthroplasty. A clinical trial is needed to further investigate the approach and ensure patient safety.
Cognition and mood in Parkinson's disease in subthalamic nucleus versus globus pallidus interna deep brain stimulation: The COMPARE Trial (2009)

There were no significant differences in the co-primary outcome measures (mood and cognition) between STN and GPi in the optimal DBS state. Adverse mood effects occurred ventrally in both targets. A worsening of letter verbal fluency was seen in STN. The persistence of deterioration in verbal fluency in the off STN DBS state was suggestive of a surgical rather than a stimulation-induced effect. Similar motor improvement were observed with both STN and GPi DBS.
Study of the Acute Effects of Povidone–Iodine on Conjunctival Bacterial Flora (2015)

There is a greater decrease in bacterial load after treatment with PI for surface cultures than for cultures obtained through a needle bore passed through the conjunctiva. PI is a superior approach to topical antibiotics to decrease conjunctival bacterial load.
Molecular Diagnosis of Congenital Immunodeficiency (2003)

The congenital immunodeficiencies are a group of inherited conditions in which there are defects of immune function. The last decade has seen the identification of most of the genes defective in these disorders (). Diagnostic genetic assays have been developed for many of these conditions so that a molecular diagnosis can be assigned to individuals and genetic testing offered for carrier status and antenatal diagnosis. Most genetic testing now involves screening the gene for the defective exon using one of a number of techniques, the most popular of which is single-stranded conformational polymorphism (SSCP) analysis (). Once the affected region is identified, direct sequence analysis can be performed to identify the precise mutation. This procedure has a number of disadvantages. If a gene has many exons, screening the gene using SSCP can be time consuming, and in cases where the clinical picture is ambiguous or atypical, can result in diagnostic delay. The sensitivity of the SSCP technique is also only 85% and thus a number of affected cases may be left undiagnosed.
Mutational analysis of the feedback sites of lysine-sensitive aspartokinase of Escherichia coli (1999)

In Escherichia coli, thrA, metLM, and lysC encode aspartokinase isozymes that show feedback inhibition by threonine, methionine, and lysine, respectively. In vitro chemical mutagenesis of the cloned lysC gene was used to identify residues and regions of the polypeptide essential for feedback inhibition by lysine. The isolated lysine-insensitive mutants were demonstrated to have missense mutations in amino acid residues 323^352, and at position 250 of aspartokinase III.
Successful Therapist–Parent Coaching: How In Vivo Feedback Relates to Parent Engagement in Parent–Child Interaction Therapy (2015)

Although behavioral parent training is considered efficacious treatment for childhood conduct problems, not all families benefit equally from treatment. Some parents take longer to change their behaviors and others ultimately drop out. Understanding how therapist behaviors impact parental engagement is necessary to improve treatment utilization. This study investigated how different techniques of therapist in vivo feedback (i.e., coaching) influenced parent attrition and skill acquisition in parent-child interaction therapy (PCIT). Participants included 51 parent-child dyads who participated in PCIT. Children (age: M = 5.03, SD = 1.65) were predominately minorities (63% White Hispanic, 16% African American or Black). Eight families discontinued treatment prematurely. Therapist coaching techniques during the first session of treatment were coded using the Therapist-Parent Interaction Coding System, and parent behaviors were coded with the Dyadic Parent-Child Interaction Coding System, Third Edition. Parents who received more responsive coaching acquired child-centered parenting skills more quickly. Therapists used fewer responsive techniques and more drills with families who dropped out of treatment. A composite of therapist behaviors accurately predicted treatment completion for 86% of families. Although group membership was correctly classified for the treatment completers, only 1 dropout was accurately predicted. Findings suggest that therapist in vivo feedback techniques may impact parents' success in PCIT and that responsive coaching may be particularly relevant.
Zealth: ZigBee-Based WBAN System for e-Health Monitoring (2017)

Electronic health (e-health) monitoring has attracted the attention of researchers due to its effectiveness in improving the services of healthcare systems. With e-health monitoring systems, one can get constant and live feedback on different health parameters without the need to go to a specialist. In this paper, we work on designing a wearable Wireless Body Area Network (WBAN) that monitors patients remotely for both preventive and diagnostic reasons. As the patient uses smart clothing that has the WBAN embedded in it, critical bio-signals are measured and communicated in real-time to a cloud server that builds a complete history of the patient's health data. An Android-based application is also developed to get easy access to the patient's history and to remotely communicate with the WBAN to control the sensors. The whole system is also supported with a pill-dispenser that can be accessed wirelessly to alert the patient about the exact times to take his/her pills. The proposed system architecture formulates the basis of a power and cost efficient practical smart clothing product.
Lymphoproliferative responses to a merozoite surface antigen of Plasmodium falciparum: preliminary evidence for seasonal activation of CD8+/HLA-DQ-restricted suppressor cells (1993)

We have investigated the phenotype of human lymphocytes responding to a defined Plasmodium falciparum malaria antigen in vitro. Cells were obtained from the peripheral blood of malaria-immune donors from an endemic area of West Africa and were tested for proliferation in response to cloned fragments of a merozoite surface protein (PfMSP1). Depletion and inhibition studies indicated that the majority of proliferating cells were CD4+ and restricted by HLA-DR or -DQ. A proportion of responding cells appeared to be CD8+, but their response was dependent on help from CD4+ cells. In two donors there was evidence that low responses could be enhanced by removal of CD8+ cells and/or blocking of antigen presentation by anti-HLA-DQ antibodies. This phenomenon was observed in cells collected during the wet (malaria transmission) season but not in cells collected from the same individual during the dry season.