gebhart/patrepeval huggingface dataset:
Degradation of newly synthesized apolipoprotein B-100 in a pre-Golgi compartment. (1990)

The synthesis and secretion of apolipoprotein (apo) B-100 have been studied in a human hepatoblastoma cell line, the Hep G2 cells. Pulse-chase analysis showed that apoB-100 was not quantitatively recovered in the culture medium. To reveal the intracellular degradation of apoB-100 prior to secretion, cells were incubated with 1 microgram/ml Brefeldin A (BFA) which impeded protein transport from the endoplasmic reticulum (ER) to the Golgi apparatus and the fate of apoB-100 retained in the cells was traced at 37 degrees C. A significant amount of intracellular apoB-100 (40-60%/h) was degraded during the chase period, whereas apoA-1 remained intact. ApoB-100 degradation was temperature dependent, no degradation was observed below 20 degrees C. This degradation process was not inhibited by chloroquine, leupeptin, pepstatin, and chymostatin, suggesting that lysosomal proteases were not involved and that apoB-100 was degraded in a pre-Golgi compartment which is either part of, or closely related to, the ER. Preincubation of cells with low density lipoproteins (LDL) induced a 22-32% increase in the degradation of apoB-100. This result raised the possibility that secretion of apoB-100 might be regulated through the intracellular degradation of apoB-100. These results suggest the existence of the degradation pathway for apoB-100 in a pre-Golgi compartment and an unique regulatory mechanism for apoB-100 secretion.
Optical Difference-Frequency Generation in Atomic Thallium Vapor (1977)

Coherent radiation at the 1.28-\ensuremath{\mu}m electric-dipole-forbidden $6^{2}P_{\frac{3}{2}}\ensuremath{-}6^{2}P_{\frac{1}{2}}$ transition in thallium vapor has been produced by the simultaneous application of a magnetic field and two collinear, overlapping laser beams nearly resonant with the $6^{2}P_{\frac{1}{2}}\ensuremath{-}7^{2}S_{\frac{1}{2}}$ and $6^{2}P_{\frac{3}{2}}\ensuremath{-}7^{2}S_{\frac{1}{2}}$ transitions, respectively. The effect of the magnetic field is to mix hyperfine levels---atomic polarization effects are negligible. The optical difference-frequency power generated at low magnetic field varies as the square of the magnetic-field component normal to the laser-beam propagation direction.
MUSCLE FATTY ACID BINDING PROTEIN IS INDUCED DURING CONDITIONS OF INCREASED FAT OXIDATION (1992)

Carey, J. O.; Neufer, P. D.; Park, H.; Farrar, R. P.; Dohn, C. L. FACSM Author Information
ChemInform Abstract: A NOVEL RING OPENING OF COUMARINS (1980)

Abstract Mit Natriumhydrid in THF werden die Cumarine (I) und auch die Furocumarine (IV) überwiegend zu den cis‐Zimtsäurederivaten (III) und (V) ringgeöffnet.
Synchronous interlocked pipelines (2004)

Locality principles are becoming paramount in controlling advancement of data through pipelined systems. Achieving fine grained power down and progressive pipeline stalls at the local stage level is therefore becoming increasingly, important to enable lower dynamic power consumption while keeping introduced switching noise under control as well as avoiding global distribution of timing critical stall signals. It has long been known that the interlocking properties of as asynchronous pipelined systems have a potential to provide such benefits. However it has not been understood how such interlocking can be achieved in synchronous pipelines. This paper presents a novel technique based on local clock gating and synchronous handshake protocols that achieves stage level interlocking characteristics in synchronous pipelines similar to that of asynchronous pipelines. The presented technique is directly applicable to traditional synchronous pipelines and works equally well for two-phase clocked pipelines based on transparent latches, as well as one-phase clocked pipelines based on master-slave latches.
Induction of Genital Immunity by DNA Priming and Intranasal Booster Immunization with a Replication-Defective Adenoviral Recombinant (1999)

Mice immunized through different routes such as i.m., intradermally, or intratracheally with a DNA vaccine to rabies virus developed high titers of serum Ab but only borderline levels of mucosal Abs determined from vaginal secretions. DNA vaccines given by either route enhanced vaginal IgA and IgG2a secretion upon a subsequent intranasal booster immunization with an E1-deleted adenoviral recombinant expressing the same Ag of rabies virus. DNA vaccine priming reduced the Ab response to the adenoviral Ags and counterbalanced the impaired B cell response to the rabies virus Ag expressed by the adenoviral recombinant in mice preimmune to adenovirus. The vaginal B cell response could further be enhanced by using the Th2-type cytokines IL-4 or IL-5 as genetic adjuvants concomitantly with the DNA vaccine before intranasal booster immunization with the recombinant vaccine.
Superconductivity and spin-density waves in multiband metals (2010)

We present a detailed description of two-band quasi-two-dimensional metals with $s$-wave superconducting (SC) and antiferromagnetic spin-density-wave (SDW) correlations. We present a general approach and use it to investigate the influence of the difference between the shapes and the areas of the two Fermi surfaces on the phase diagram. In particular, we determine the conditions for the coexistence of SC and SDW orders at different temperatures and dopings. We argue that a conventional $s$-wave SC order coexists with SDW order only at very low $T$ and in a very tiny range of parameters. An extended $s$-wave superconductivity, for which SC gap changes sign between the two bands, coexists with antiferromagnetic SDW over a much wider range of parameters and temperatures but even for this SC order the regions of SDW and SC can still be separated by a first-order transition. We show that the coexistence range becomes larger if SDW order is incommensurate. We apply our results to iron-based pnictide materials, in some of which coexistence of SDW and SC orders has been detected.
Oxidative polycyclizations with rhenium(VII) oxides (2002)

Abstract The consecutive oxidative polycyclization reaction with rhenium(VII) oxides represents a highly stereoselective synthetic tool by which polyenes that contain a bis-homoallylic alcohol can be transformed into poly-THF products in a single step. On the basis of a detailed study with model substrates, a set of rules is proposed to predict product configurations in the polycyclization reactions with trifluoroacetylperrhenate. This methodology is exceptionally useful for the synthesis of polyoxygenated carbon skeletons that contain many stereogenic centers, and for the Annonaceous acetogenins in particular. Many of these potent antitumor agents, including solamin, reticulatacin, asimicin, bullatacin, trilobin, trilobacin, squamotacin, rolliniastatin, uvaricin, rollidecins C and D, mucocin, goniocin, and cyclogoniodenin T, as well as chemical libraries of non-natural analogs, were synthesized using the oxidative polycyclization reaction in combination with the Sharpless AD and AE reactions.
A stateful multicast access control mechanism for future metro‐area‐networks (2003)

Multicasting is a necessity for a broadband metro‐area‐network. Discusses the security problems with current multicast protocols. To make the multicast delivery infrastructure more secure and reliable, a stateful multicast access control mechanism, based on MAPE, is proposed. This mechanism expands the current forwarding procedure of a layer 2 switch so that stateful multicast access control can be carried out at the very edge of the metro area network. The architecture of MAPE is discussed in detail, as well as the states maintained and messages exchanged. Further explains that the scheme is flexible and scalable.
Direct in situ GDD measurement in optical coating process (2015)

In the presented work a fast frequency domain measurement system to determine group delay (GD) and group delay dispersion (GDD) of optical coatings is proposed. The measurements are performed in situ directly on moving substrates during the thin film coating process. The method is based on a Michelson interferometer, which is equipped with a high power broad band light source and a fast spectrometer. Especially for the production of chirped mirrors it is advantageous to obtain group delay and group delay dispersion data of the last layers. This additional information allows for online corrections of coating errors to enhance the precision of complex interference filters for short pulse applications.
A Simple and Efficient Plasmonic Sensor in Light Diffusive Polymer Fibers (2021)

A low-cost plasmonic sensor based on a polymeric light diffusive optical fiber (LDF) has been designed, realized, and experimentally tested. The developed surface plasmon resonance (SPR) sensor has been realized by sputtering a gold nanofilm on the LDF. The work also presents a simple modal filter, realized by covering the LDF with an aqueous solution. Notably, this modal filter improves the signal-to-noise ratio (SNR) of the SPR sensor thanks to the filtering of the higher modes, without losing its sensitivity.
Triggerable RNA Nanodevices (2016)

The targeted and conditional activation of pharmaceuticals is an increasingly important feature in modern personalized medicine. Nucleic acid nanoparticles show tremendous potential in this exploit due to their programmability and biocompatibility. Among the most powerful nucleic acid specific treatments is RNA interference-based therapeutics. RNA interference is a naturally occurring phenomenon in which specific genes are effectively silenced. Recently we have developed two different strategies based on customized multivalent nucleic acid nanoparticles with the ability to conditionally activate RNA interference in diseased cells as well as elicit detectable fluorescent responses.[1,2] These novel technologies can be further utilized for the simultaneous delivery and conditional intracellular activation of multiple therapeutic and biosensing functions to combat various diseases.
Preparation of wood-like structured copper with superhydrophobic properties (2015)

Here, we report a method to use natural wood lauan as a template to fabricate superhydrophobic biomorphic copper on a carbon substrate (Cu/C). First, a carbon substrate with the microstructure of lauan was obtained by sintering lauan in an oxygen-free environment. A biomorphic Cu/C material was then obtained by immersing this carbon substrate into a Cu(NO3)2 solution and sintering. Finally, the hydrophobicity of the products obtained was investigated. The Cu/C retained the microstructure of the wood well. It exhibited excellent superhydrophobicity after it was modified with fluorine silane. The water contact angle of this modified Cu/C reached 160°.
Flame Propagation Studies in a Four-Valve Pentroof-Chamber Spark Ignition Engine (1992)

&lt;div class="htmlview paragraph"&gt;Heat release analysis, ion current and laser Doppler velocimetry methods are combined to examine the effect of pre-spark turbulent mixture motion on flame propagation and combustion characteristics in the four-valve pentroof combustion chamber of a spark ignition engine. Two inlet port configurations leading to different strengths of induction-generated tumbling vortices are considered with emphasis on lean mixture operation under partial load conditions. The results show a good correlation between mixture turbulent characteristics at ignition and flame development, flame propagation rate, combustion duration and cyclic variability. It is shown that turbulence enhancement through induction-generated tumble counterbalances the lean mixture ignition delay by enhancing the flame propagation speed, leading to extension of the engine lean operating limits.&lt;/div&gt;
Association of Shear Stress with Subsequent Lumen Remodeling in Hemodialysis Arteriovenous Fistulas (2022)

Higher wall shear stress and lower oscillatory shear index were associated with greater lumen expansion after AVF creation surgery.
Specific Blocking to Improve Biopanning in Biological Samples such as Serum and Hybridoma Supernatants (2001)

Screening phage-displayed peptide libraries (biopanning) is an important technique for acquiring peptide ligands and for mapping peptide epitopes recognized by antibodies (Ab). In biological samples, other materials, not only contaminants but also natural constituents, often interfere with biopanning. Capture methods use anchoring Abs that reduce the need for purification of the intended panning target from a crude sample. This capture method is analogous to sandwich ELISA. However, when the target molecule concentration is low in the initial mixture, the panning of a captured target often yields epitopes that bind to the capture antibody rather than the target of interest. We have developed a methodology that utilizes specific blocking reagents of the capture Ab to extend the sensitivity and applicability of the capture approach to phage panning. A flowchart is presented to enable the worker to begin panning with the simplest approach and then to employ sandwich capture and specific blocking reagents as necessary.
The thermal properties of poly(oxy‐1,4‐benzoyl), poly(oxy‐2,6‐naphthoyl), and its copolymers (1990)

Abstract The thermal properties, i.e., heat capacity, enthalpy, entropy, and Gibbs function, and the transition behavior of the copolymer system of 4‐hydroxybenzoic acid and 2,6‐hydroxynaphthoic acid have been studied based on differential scanning calorimetry. The heat capacities of the glass, crystal, and anisotropic melt are shown to be largely additive on a molar basis. Additivity is lost in the two transition regions, glass transition and disordering transition. Isothermal crystallization experiments on the copolymers revealed the existence of two types of crystals which melt at high temperature (fast‐grown crystals) and low temperature (slowly grown crystals). The ATHAS computation method is used to bring heat capacities of the solid state into agreement with approximate frequency spectra. The changes in heat capacity at the glass transitions occur at 434°K for the poly(oxy‐1,4‐benzoyl) [33.2 J/(K mol)] and at 420°K for poly(oxy‐2,6‐naphthoyl) [46.5 J/(K mol)]. The copolymers have a transition range of above 100°K. The anisotropic melt is linked to the well‐known condis state of poly(oxy‐1,4‐benzoyl) by a continuous changes in disorder and mobility without an additional first‐order transition.
Reducing Multicast Redundancy and Latency in Wireless Mesh Networks (2009)

In wireless mesh networks, each node can be equipped with multiple network interface cards tuned to different channels. In this paper, we study the problem of collision-free multicast in multi-interface multi-channel wireless mesh networks. The concept of interface redundancy's proposed as a new criterion for the multicast redundancy in wireless mesh networks, and we prove that building a multicast tree with the minimum interface redundancy is a NPhard problem. We also prove that the minimum-latency multicasting problem in multi-channel wireless mesh networks is NP-hard. We present two heuristic-based algorithms which jointly reduce the interface redundancy and the multicast latency. Finally, the simulation results prove the effectiveness of our approach.
Nomenclature and graphic representations for chemically modified polymers (IUPAC Recommendations 2014) (2015)

Abstract A new source-based nomenclature system is described which indicates that a particular polymer has been chemically modified. A connective within the name of a polymer, - mod -, is introduced for this purpose as in poly[(A)- mod -(B)]. The system is intended to be used in accordance with source-based naming of polymers but also provides for the use of structure-based names when it is unavoidable. It embraces: (1) modification of a constitutional unit into another, the unique structure of which is known; and (2) a more general modification of a constitutional unit resulting in any one of a number of possible structures. In addition, a new symbol, ∼&gt;, is proposed for use in graphic representations of the structure of modified polymers.
Dendrimers in Supramolecular Chemistry:  From Molecular Recognition to Self-Assembly (1997)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDendrimers in Supramolecular Chemistry: From Molecular Recognition to Self-AssemblyFanwen Zeng and Steven C. ZimmermanView Author Information Department of Chemistry, 600 South Mathews Avenue, University of Illinois, Urbana, Illinois 61801 Cite this: Chem. Rev. 1997, 97, 5, 1681–1712Publication Date (Web):August 5, 1997Publication History Received8 January 1997Revised12 April 1997Published online5 August 1997Published inissue 1 August 1997https://pubs.acs.org/doi/10.1021/cr9603892https://doi.org/10.1021/cr9603892research-articleACS PublicationsCopyright © 1997 American Chemical SocietyRequest reuse permissionsArticle Views9187Altmetric-Citations1269LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Copolymers,Dendrons,Molecules,Peptides and proteins,Polymers Get e-Alerts
Adaptive electricity scheduling in microgrids (2013)

Microgrid (MG) is a promising component for future smart grid (SG) deployment. The balance of supply and demand of electric energy is one of the most important requirements of MG management. In this paper, we present a novel framework for smart energy management based on the concept of quality-of-service in electricity (QoSE). Specifically, the resident electricity demand is classified into basic usage and quality usage. The basic usage is always guaranteed by the MG, while the quality usage is controlled based on the MG state. The microgrid control center (MGCC) aims to minimize the MG operation cost and maintain the outage probability of quality usage, i.e., QoSE, below a target value, by scheduling electricity among renewable energy resources, energy storage systems, and macrogrid. The problem is formulated as a constrained stochastic programming problem. The Lyapunov optimization technique is then applied to derive an adaptive electricity scheduling algorithm by introducing the QoSE virtual queues and energy storage virtual queues. The proposed algorithm is an online algorithm since it does not require any statistics and future knowledge of the electricity supply, demand and price processes. We derive several "hard" performance bounds for the proposed algorithm, and evaluate its performance with trace-driven simulations. The simulation results demonstrate the efficacy of the proposed electricity scheduling algorithm.
Safety and radiosensitizing efficacy of sanazole (AK 2123) in oropharyngeal cancers: Randomized controlled double blind clinical trial (2006)

The study validates the usefulness of sanazole for initial loco-regional control in oropharyngeal cancers.
Promoting access to services: the development of a new screening tool (2006)

Karen McKenzie and Donna Paxton outline the development of a questionnaire. The aim was to offer services a relatively simple, non-threatening way of confirming whether a person has a learning disability. It could also potentially save valuable time for over-stretched learning disability practitioners
Combating Software and Sybil Attacks to Data Integrity in Crowd-Sourced Embedded Systems (2014)

Crowd-sourced mobile embedded systems allow people to contribute sensor data, for critical applications, including transportation, emergency response and eHealth. Data integrity becomes imperative as malicious participants can launch software and Sybil attacks modifying the sensing platform and data. To address these attacks, we develop (1) a Trusted Sensing Peripheral (TSP) enabling collection of high-integrity raw or aggregated data, and participation in applications requiring additional modalities; and (2) a Secure Tasking and Aggregation Protocol (STAP) enabling aggregation of TSP trusted readings by untrusted intermediaries, while efficiently detecting fabricators. Evaluations demonstrate that TSP and STAP are practical and energy-efficient.
Heterogeneous Intermolecular Hydroamination of Terminal Alkynes with Aromatic Amines. (2006)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Research on Combustion Oscillation Generation Mechanism (2016)

Self-excited vibration called the combustion vibration occurs in the combustion apparatus. The vibration and noise adversely affect combustion apparatuses. Therefore it is necessary to control the generation of vibration. But the mechanism of the onset of vibration has not been sufficiently elucidated and countermeasures have not been established. The purpose of our research is to analyze the mechanism of generating the combustion vibration using a cellular automaton method (abbrev. CA). Since a combustion apparatus is in three-dimensions it is difficult to analyze. In this study we analyzed the combustion vibration with a Rijke tube which can be treated in a one-dimensional model. At first, We established the rule of the CA method.In addition, we developed a calculation model using CA method. As a result, we was able to confirm a state of the self-excitation vibration. But it became a different result from the actual experiment.
ROBTET: a new teleoperated system for live-line maintenance (2002)

This paper presents a new teleoperated system for live-line maintenance developed for the IBERDROLA electrical utility. Its aim is to increase the safety and comfort of the workers and the overall efficiency, as well as to reduce labour requirements. Its design is based on other already developed systems but with a new approach. It consists of a pair of hydraulic-driven master-slave teleoperated manipulators, placed on top of an insulated boom, which execute directly on the hot line, the tasks commanded via master arms by an operator on the ground. Telepresence of the operator is accomplished through a 3-D vision system, a multimedia interface and the force-feedback capabilities of the manipulators. This paper describes in detail all these elements, as well as the teleoperation architecture that interface them, with special attention to the telepresence issues which seem to lack in similar systems.