gebhart/patrepeval huggingface dataset:
Petite tordeuse Grapholita lobarzewskii: lutte par la technique de confusion et dynamique des populations (2001)

Technique de confusion experimentee contre la petite tordeuse des fruits dans un verger de pommiers a l'aide de diffuseurs Isomate-M Plus et Isomate-OFM Rosso. Cette technique a permis de maintenir le ravageur a un niveau bas sans toutefois eliminer completement les attaques.
Preliminary study on the use of 3D printed biodegradable polymeric sheet for the manufacturing of medical prostheses by SPIF (2022)

Incremental Sheet Forming (ISF) and Fused Deposition Modelling (FDM) of polymers have both an edge over conventional manufacturing by their ability to directly get complex structures without the need of a mold or a die. Obtaining biocompatible polymer blanks for ISF is not always as easy as it could be expected. Concerning nowadays FDM offers a good opportunity to print biocompatible polymer sheets as blanks to next be formed by ISF. Exploring the combination of FDM and ISF for two biodegradable polymers (Polylactic acid (PLA) and Polycaprolactone (PCL)) is the objective of this work. An analysis of the initial printed sheets in terms of thickness uniformity and surface roughness was carried out. Truncated cone shape with fixed slope angle geometries in a CNC machine were formed. The ISF process parameters modified were the traditional: step down, feed rate and spindle speed. As saved outputs there are: Forming Forces, Maximum Temperature, Surface Integrity, Surface Roughness and Shape Accuracy. After this first approach, a good feasibility process window was established for being used on prosthesis manufacturing of PCL. On the contrary, the feasibility window for PLA is limited because of its low formability. The first results of the combination of both additive manufacturing processes are interesting and deserve further studies to evaluate more in depth the behaviors and the forming mechanism of these materials.
The Accuracy of Subacromial Injections: A Prospective Randomized Magnetic Resonance Imaging Study (2006)

Level II.
Entity-Aware Dependency-Based Deep Graph Attention Network for Comparative Preference Classification (2020)

This paper studies the task of comparative preference classification (CPC). Given two entities in a sentence, our goal is to classify whether the first (or the second) entity is preferred over the other or no comparison is expressed at all between the two entities. Existing works either do not learn entity-aware representations well and fail to deal with sentences involving multiple entity pairs or use sequential modeling approaches that are unable to capture long-range dependencies between the entities. Some also use traditional machine learning approaches that do not generalize well. This paper proposes a novel Entityaware Dependency-based Deep Graph Attention Network (ED-GAT) that employs a multihop graph attention over a dependency graph sentence representation to leverage both the semantic information from word embeddings and the syntactic information from the dependency graph to solve the problem. Empirical evaluation shows that the proposed model achieves the state-of-the-art performance in comparative preference classification.
Anti-windup dual-loop control of DFIG under unbalanced voltage conditions (2012)

This paper proposes a new anti-windup dual-loop control of doubly-fed induction generator (DFIG) under unbalanced grid voltage conditions. System behavior and controller operation of windup under unbalanced conditions are illustrated. To avoid the windup problem, a new extraction method based on Discrete Fourier Series (DFS) is proposed to decouple the sequence components indifferent to sub- or super- synchronous operation of the DFIG system. A dual loop control is developed for the decoupled positive and negative sequences. The positive sequence control loop is responsible for the conventional torque control and the additional negative sequence control loop is responsible for the minimization of 2 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">nd</sup> harmonic in torque pulsation and dc link voltage fluctuation. Simulation results using Matlab/SimPowerSystems library are presented for the built-in single loop and modified dual-loop 9 MW DFIG wind generation systems under unbalanced grid voltage condition to demonstrate the system operation and validate the proposed dual-loop control scheme.
Abstract 2688: Drugging MYCN through an allosteric transition in Aurora A kinase (2014)

Abstract MYC genes contribute to a range of cancers including neuroblastoma, where amplification of MYCN confers a poor prognosis. Proteolytic degradation of MYCN protein is regulated in part by a kinase-independent function of Aurora kinase A. We describe a class of inhibitors that disrupts the native conformation of Aurora A and causes degradation of MYCN protein across MYCN-expressing neuroblastoma cell lines. Comparison of co-crystal structures with structure- activity relationships across multiple inhibitors and chemotypes, coupled with mechanistic studies and biochemical assays, delineates an Aurora A conformation-specific effect on proteolytic degradation of MYCN, rather than simple nanomolar-level inhibition of Aurora A kinase activity. This new class of inhibitors, which disrupts stabilizing interactions between Aurora A and MYCN, represents candidate agents to target MYCN-driven and potentially MYC-driven cancers. Citation Format: William C. Gustafson, Justin G. Meyerowitz, Erin A. Nekritz, Elise A. Charron, Yvan Chanthery, Erin Simonds, Katherine Matthay, Nicholas Hertz, Kevan Shokat, William A. Weiss. Drugging MYCN through an allosteric transition in Aurora A kinase. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 2688. doi:10.1158/1538-7445.AM2014-2688
Microbiome and Cardiovascular Disease in CKD (2018)

Patients with CKD exhibit a disproportionate burden of cardiovascular mortality, which likely stems from the presence of unique, nontraditional risk factors that accompany deteriorating kidney function. Mounting evidence suggests that alterations to the intestinal microbiome in CKD may serve as one such risk factor. The human intestinal tract is home to >100 trillion micro-organisms made up of a collection of commensal, symbiotic, and pathogenic species. These species along with their local environment constitute the intestinal microbiome. Patients with CKD show intestinal dysbiosis, an alteration of the gut micro-organism composition and function. Recent evidence links byproducts of intestinal dysbiosis to vascular calcification, atherosclerosis formation, and adverse cardiovascular outcomes in CKD. CKD-associated intestinal dysbiosis may also be accompanied by defects in intestinal barrier function, which could further enhance the negative effects of pathogenic intestinal bacteria in the human host. Thus, intestinal dysbiosis, defective intestinal barrier function, and a reduced capacity for clearance by the kidney of absorbed bacterial byproducts may all potentiate the development of cardiovascular disease in CKD. This narrative review focuses on microbiome-mediated mechanisms associated with CKD that may promote atherosclerosis formation and cardiovascular disease. It includes (<i>1</i>) new data supporting the hypothesis that intestinal barrier dysfunction leads to bacterial translocation and endotoxemia that potentiate systemic inflammation, (<i>2</i>) information on the accumulation of dietary-derived bacterial byproducts that stimulate pathways promoting atheromatous changes in arteries and cardiovascular disease, and (<i>3</i>) potential interventions. Despite great scientific interest in and a rapidly growing body of literature on the relationship between the microbiome and cardiovascular disease in CKD, many important questions remain unanswered.
Physicochemical Studies on the Decomposition of <i>p</i>-Aminosalicylic Acid and its Salts. II (1961)

Following the previous report on the reaction velocity constant k to changes in pH in aqueous solution with constant ionic strength, in the decarboxylation reaction of p-aminosalicylic acid, experiments were carried out on variation in the concentration of sodium p-aminosalicylate and the minimum rate of decomposition was obtained in 0.5M concentration, as shown in Fig. 1. Various amounts of acetic acid-sodium acetate buffer were tested at a constant pH, as indicated in Table III, and the value of b=1.098 of equation (1) was obtained. The effect of the concentration of p-aminosalicylate was tested and the values of kobs. listed in Table I were obtained. From kobs. of 0.3M solutions at various temperatures, functions of temperature and H3O+ concentration were calculated and the values were interpolated in equation (2), from which equation (2′) was obtained. From this equation, kcalc. was calculated. The values of Eobs≠., ΔH≠, ΔS≠, and ΔR≠ at various temperatures were calculated from Eyring's absolute reaction rate theory and the values became the lowest at 0.5M concentration, as indicated in Table II.
Lactobacillus helveticus-Fermented Milk Whey Suppresses Melanin Production by Inhibiting Tyrosinase through Decreasing MITF Expression (2020)

Whey obtained from milk fermented by the <i>Lactobacillus helveticus</i> CM4 strain (LHMW) has been shown to improve skin barrier function and increase skin-moisturizing factors. In this study, we investigated the effects of LHMW on melanin production to explore the additional impacts of LHMW on the skin. We treated mouse B16 melanoma cells with α-melanocyte-stimulating hormone (α-MSH) alone or simultaneously with LHMW and measured the amount of melanin. The amount of melanin in B16 cells treated with α-MSH significantly increased by 2-fold compared with that in control cells, and tyrosinase activity was also elevated. Moreover, treatment with LHMW significantly suppressed the increase in melanin content and elevation of tyrosinase activity due to α-MSH. LHMW also suppressed the α-MSH-induced increased expression of tyrosinase, tyrosinase-related protein 1 (TRP1), and dopachrome tautomerase (DCT) at the protein and mRNA levels. Furthermore, the mRNA and protein microphthalmia-associated transcription factor (MITF) expression levels were significantly increased with treatment with α-MSH alone, which were also suppressed by LHMW addition. LHMW suppression of melanin production is suggested to involve inhibition of the expression of the tyrosinase gene family by lowering the MITF expression level. LHMW may have promise as a material for cosmetics with expected clinical application in humans.
Selective Treatment of Atherosclerotic Plaques Using Nanosecond Pulsed Laser with a Wavelength of 5.75 µm for Less-invasive Laser Angioplasty (2009)

XeCl excimer laser coronary angioplasty (ELCA), has gained more attention for the treatment of serious stenosis blocked by plaque. Low degrees of thermal damage after ablation of atherosclerotic plaques have been achieved by ELCA. However, the large number of risks associated with the procedure, for example, dissections or perforations of the coronary arteries limits its application. The laser treatment technique with high ablation efficiency but low arterial wall injury is desirable. Mid-infrared laser with a wavelength of 5.75 Pm is selectively well absorbed in C=O stretching vibration mode of ester bonds in cholesteryl ester. We studied the effectiveness of nanosecond pulsed laser at 5.75 Pm for novel less-invasive laser angioplasty. In this study, we used a mid-infrared tunable solid-state laser which is operated by difference-frequency generation, at 5.75 Pm, a pulse width of 5 ns and a pulse repetition rate of 10 Hz as a treatment light source, and a thoracic aorta of WHHLMI rabbit as an atherosclerosis model. As a result, less-invasive treatment parameters for removing atherosclerotic plaques in a wet condition were confirmed. This study shows that the nanosecond pulsed laser irradiation at 5.75 Pm is a powerful tool for selective and less-invasive treatment of atherosclerotic plaques.
Clinical correlation of influenza and respiratory syncytial virus load measured by digital PCR (2019)

Acute respiratory tract infections are a major cause of respiratory morbidity and mortality in pediatric patients worldwide. However, accurate viral and immunologic markers to predict clinical outcomes of this patient population are still lacking. Droplet digital PCR assays for influenza and respiratory syncytial virus (RSV) were designed and performed in 64 respiratory samples from 23 patients with influenza virus infection and 73 samples from 19 patients with RSV infection. Samples of patients with hematologic malignancies, solid tumors, or sickle cell disease were included. Clinical information from institutional medical records was reviewed to assess disease severity. Samples from patients with fever or respiratory symptoms had a significantly higher viral loads than those from asymptomatic patients. Samples from patients with influenza virus and RSV infection collected at presentation had significantly higher viral loads than those collected from patients after completing a course of oseltamivir or ribavirin, respectively. RSV loads correlated positively with clinical symptoms in patients ≤5 years of age, whereas influenza viral loads were associated with clinical symptoms, irrespective of age. Patients receiving antivirals for influenza and RSV had a significant reduction in viral loads after completing therapy. Digital PCR offers an effective method to monitor the efficacy of antiviral treatment for respiratory tract infections in immunocompromised hosts.
PMD-insensitive SCM optical receiver using polarization diversity (2002)

Subcarrier multiplexing (SCM) optical systems with high subcarrier frequencies are susceptible to power fading caused by fiber polarization-mode dispersion (PMD). In this letter, an SCM optical receiver free of carrier fading is proposed and demonstrated using polarization diversity. Unlike conventional PMD compensators, this setup does not require a tunable optical delay line.
Microwave enhanced electroanalysis of formulations: processes in micellar media at glassy carbon and at platinum electrodes (2005)

The direct electroanalysis of complex formulations containing alpha-tocopherol (vitamin E) is possible in micellar solution and employing microwave-enhanced voltammetry. In the presence of microwave radiation substantial heating and current enhancement effects have been observed at 330 microm diameter glassy carbon electrodes placed into a micellar aqueous solution and both hydrophilic and highly hydrophobic redox systems are detected. For the water soluble Fe(CN)(6)(3-/4-) redox system in micellar aqueous solutions of 0.1 M NaCl and 0.1 M sodium dodecylsulfate (SDS) at low to intermediate microwave power, thermal effects and convection effects are observed. At higher microwave power, thermal cavitation is induced and dominates the mass transport at the electrode surface. For the micelle-soluble redox systems tert-butylferrocene and 2,5-di-tert-butyl-1,4-benzoquinone, strong and concentration dependent current responses are observed only in the presence of microwave radiation. For the oxidation of micelle-soluble alpha-tocopherol current responses at glassy carbon electrodes are affected by adsorption and desorption processes whereas at platinum electrodes, analytical limiting currents are obtained over a wide range of alpha-tocopherol concentrations. However, for the determination of alpha-tocopherol in a commercial formulation interference from proteins is observed at platinum electrodes and direct measurements are possible only over a limited concentration range and at glassy carbon electrodes.
Non-Working Contact Does Not Initiate Primary Occlusal Trauma (2008)

Purpose: The role of occlusion in the progression of periodontal disease has long been discussed, and occlusal trauma is considered a cofactor that allows absorption of the alveolar bone, which might temporarily or permanently increase tooth mobility. In general practice, occlusion has been evaluated during border and tapping movements to detect and remove premature and non-working contacts. Since previous studies have compared occlusion with periodontal tissue that might have a periodontal problem, it has been difficult to differentiate primary and secondary occlusal trauma. This study focused on primary occlusal trauma and evaluates the relationship between tooth contact during lateral excursions and periodontal status.Methods: Teeth without periodontal disease were studied in 50 men and 50 women and classified into two groups according to the presence or absence of non-working contacts. Probing depth, clinical attachment levels, and tooth mobility were compared between the two groups.Results: There was no significant difference in the Periotest value, probing depths and clinical attachment levels of the first and the second molars between teeth with and without non-working contacts.Conclusion: The results of this study pose questions regarding the importance of examinations of tooth contact during lateral excursion and occlusal adjustment based on this examination. Since the significance of non-working contact as a causative factor of occlusal trauma was not proved, the validity of occlusal adjustment for eliminating non-working contact is questionable.
Antitumor Agents. 274. A New Synthetic Strategy for E-Ring SAR Study of Antofine and Cryptopleurine Analogues (2010)

A new versatile synthetic methodology for the synthesis of enantiomerically pure natural phenanthroindolizidines and phenanthroquinolizidines has been established and described. Natural products R-antofine and R-cryptopleurine, as well as a novel E-ring expanded analogue 13c (E7), 12-oxo-S-antofine (17), and 12N-methyl-12-aza-S-antofine (18) were synthesized with the new method. This strategy will greatly facilitate future SAR studies on the natural alkaloids with E-ring variations.
Mixed Multiplicative Factor Analysis Model for Air Pollution Exposure Assessment (2006)

∗Harvard School of Public Health, mkaramit@hsph.harvard.edu †Harvard University, bcoull@hsph.harvard.edu ‡Harvard School of Public Health and Dana Farber Cancer Institute, catalano@hsph.harvard.edu ∗∗Harvard School of Public Health, jgodlesk@hsph.harvard.edu This working paper is hosted by The Berkeley Electronic Press (bepress) and may not be commercially reproduced without the permission of the copyright holder.
Reflectance Spectra and the Coordination of Divalent Metal Ions in 5-Trifluoromethyltetrazole Complexes (1965)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReflectance Spectra and the Coordination of Divalent Metal Ions in 5-Trifluoromethyltetrazole ComplexesArlo D. Harris, Hans B. Jonassen, and Ronald D. ArcherCite this: Inorg. Chem. 1965, 4, 2, 147–149Publication Date (Print):February 1, 1965Publication History Published online1 May 2002Published inissue 1 February 1965https://pubs.acs.org/doi/10.1021/ic50024a004https://doi.org/10.1021/ic50024a004research-articleACS PublicationsRequest reuse permissionsArticle Views32Altmetric-Citations19LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
[O2‐02‐02]: What causes and how can we prevent cognitive deficits in Alzheimer's (AD)? (2005)

Genetic defects in postsynaptic pathways regulating dendritic spine actin assembly are implicated in mental retardation. Genetic defects causing later onset cognitive deficits (AD) result in an age-dependent increase in soluble Aβ aggregates, inflammation, oxidative damage and defects in the same postsynaptic pathways crucial for synaptogenesis and synaptic plasticity. This leads to cognitive deficits preceding extensive amyloid deposits in animal models with amyloid precursor (APP) overexpression and Down's syndrome (DS). Thus, AD, young DS and APP transgenic mice share elevated soluble Abeta, oxidative damage, dendritic spine and cognitive deficits and loss of the actin-regulatory spine protein, drebrin. To prevent these defects, we tested two candidates (DHA and curcumin) with epidemiological support for low cost, safe and multiple activities in animal models based on Abeta as an initiating factor. APP transgenics or soluble Aβ CNS-infused rodents showed oxidative damage, inflammation, Aβ deposits, loss of critical postsynaptic proteins (drebrin, PSD-95 and NR2B) and cognitive deficits. Treatment with the NSAID/antioxidant curcumin in the diet suppressed these endpoints, including Aβ aggregates in the Aβ infusion mode, in vitro, and in aging and aged APPsw transgenic mice. Most endpoints, notably drebrin and other postsynaptic marker loss, were grossly exacerbated by late onset dietary depletion of readily oxidizable DHA and restored by DHA and/ or curcumin treatment. An examination of the mechanisms involved in vitro and in vivo implicated alterations in the PAK<>LIMK<>cofilin pathway involved in mental retardation, control of caspase activation and synaptogenesis. We demonstrated the efficacy of two natural compounds with broad spectrum protective effects, low cost and very favorable toxicity profiles, the turmeric curry spice extract, curcumin, and the omega-3 fatty acid, DHA. By different mechanisms, both compounds have favorable epidemiology and are neuroprotective with anti-inflammatory, antioxidant and multiple anti-amyloid activities. Both impact and synergize in protecting against a post-synaptic attack by Aβ on a pathway relevant to synaptogenesis, synaptic plasticity, AD pathology and cognitive impairment. Collectively, these data advocate for clinical trials and ultimately, primary prevention trials using these compounds.
Stochastic delays in transportation terminals : new results in the theory and application of bulk queues (1981)

Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Civil Engineering, 1981.
A Location Based Time and Attendance System (2013)

Time and Attendance System provides many benefits to organizations. It enables an employer to have full control of all employees working hours. It helps control labour costs by reducing over-payments, which are often caused by transcription error, interpretation error and intentional error. Manual processes are also eliminated as well as the staff needed to maintain them. It is often difficult to comply with labour regulation, but a time and attendance system is invaluable for ensuring compliance with labour regulations regarding proof of attendance.
Magnetically recyclable core–shell nanocatalysts for efficient heterogeneous oxidation of alcohols (2014)

We describe the designed fabrication of magnetically recyclable core–shell Pd nanocatalysts for the efficient oxidation of alcohols under base-free reaction conditions in water.