gebhart/patrepeval huggingface dataset:
Rapid Design and Production of Soft Actuators using Dynamic Modeling and Additive Manufacturing for Underwater Soft Actuators (2023)

Soft robotic actuators have repeatedly demonstrated their utility for underwater manipulation, particularly in the deep sea with delicate biological creatures and fragile artifacts. Up to this point, soft robotic actuators and gripping modules have been limited to relatively small prototypes that are on the same scale as a human hand. Scaling soft robotic grippers to larger sizes is a non-trivial task due to two major challenges: design and manufacturing. In this work, we present a complete and streamlined workflow of modeling, manufacturing, and testing scalable soft actuators that are directly produced using additive manufacturing methods and finite element modeling (FEA). The presented workflow is an iterative approach that uses information gathered from the FEA’s simulation to further improve the simplified known initial model. To demonstrate this new workflow, a series of soft actuator designs were modeled, created and tested. Additionally, a more complex theoretical actuator design that has a non-uniform bending geometry is created and modeled. Once the actuator design matches what is desired, additive manufacturing is used to physically create it. Using this full process, an actuator design is easily scaled to almost three times its original length and is manufactured in under 36 hours. The scaled up actuators are arranged in a custom full gripping array to grasp a cylinder underwater in a predictive manner.
Correction: Viral MHC Class I-like Molecule Allows Evasion of NK Cell Effector Responses In Vivo (2015)

Pyzik, M., A. A. Dumaine, B. Charbonneau, N. Fodil-Cornu, S. Jonjic, and S. M. Vidal. 2014. Viral MHC class I–like molecule allows evasion of NK cell effector responses in vivo. J. Immunol . 193: [6061–6069][1].

The name of the second author was published incorrectly. The middle initial “A
Controlling Crystal Orientation in Zeolite MFI Thin Films by Direct In Situ Crystallization (2001)

A systematic study was carried out on the synthesis of oriented continuous zeolite MFI thin films on stainless steel substrate by direct in-situ crystallization, and clear correlation was obtained between crystal orientation in the zeolite film and the composition of the synthesis solution. Within the synthesis system of TPAOH:NaOH:TEOS:H2O:NaCl, OH-/Si and Na+/TPA+ ratios play a critical role in controlling crystal orientation. For sodium-free or low sodium syntheses, only random-oriented films are formed at OH-/Si ≥ 0.64, (a, b)-oriented films at 0.64 > OH-/Si > 0.5 or at 0.2 ≥ OH-/Si > 0.1, and b-oriented films at 0.5 ≥ OH-/Si > 0.2. For a given OH-/Si ratio, addition of Na+ leads to change of crystal orientation from b-oriented, to (a, b)-oriented, to (a, b, c)-oriented, and eventually to random-oriented.
Inter-band Tunnel Transistor Architecture using Narrow Gap Semiconductors (2009)

The inter-band tunnel transistor (TFET) architecture features a sub-kT/q sub-threshold slope operation and can potentially support high ION/IOFF ratios over small gate voltages. Based on two-dimensional numerical simulations, we investigate TFET in various material systems ranging from silicon to indium arsenide. TFET performance can be enhanced when heterojunctions are employed at the source side to enhance tunneling, nonequilibrium carrier population is maintained in the channel and one dimensional tunneling junction are incorporated. Mixed mode circuit simulations using TFETs highlight the impact of feed forward gate-to-drain capacitance in these devices during transient switching operation and reveal important differences with MOSFETs. Narrow gap semiconductors with low density of states are projected as viable candidates to implement TFET architecture in sustaining an aggressive supply voltage scaling roadmap for future digital logic applications
Compilation Techniques for Optimizing Communication on Distributed-Memory Systems (1993)

Communication overhead can significantly impact the performance execution of programs on distributed-memory systems.
Lipid domains in membranes. Evidence derived from structural perturbations induced by free fatty acids and lifetime heterogeneity analysis. (1980)

The interaction of free fatty acids with cell membranes and lipid bilayers was studied by monitoring the emission polarization changes of the fluorescent probes 1,6-diphenyl-1,3,5-hexatriene (DPH) and 8-anilino-1-naphthalene sulfonate (ANS). It was found that cis unsaturated fatty acids incorporated into plasma membranes reduced DPH and increased ANS polarization, while trans-unsaturated and saturated fatty acids had no effect on DPH, but did increase ANS polarization. Although in fluid lipid vesicles, both types of fatty acids decreased DPH polarization, in mixed phase vesicles (dilauroyl phosphatidylcho1ine:dipalmitoy1 phosphatidylcholine) polarization changes of ANS and DPH were similar to that observed in plasma membranes. Alteration in the dimyristoyl phosphatidylcholine phase transition as a function of fatty acid type was used to study the fluid-solid partition behavior in lipid bilayers. Using solution theory, the shift in the transition midpoint temperature was used to infer that the el-unsaturated fatty acids partition into fluid domains while the tmns-unsaturated and saturated fatty acids preferentially partition into solid-like domains. The fluorescent lifetime of DPH in membranes and vesicles was measured by the phase-modulation technique. The results were analyzed in terms of site heterogeneity and indicate that while DPH decay in single phase vesicles is monoexponential, a considerable degree of heterogeneity is observed in mixed phase vesicles and plasma membranes. In particular, evidence is obtained for a DPH binding site which corresponds to the interface between lipid domains. These results, together with the free fatty acid effects, are interpreted in terms of lipid domains in membranes.
Scaffold Properties Are a Key Determinant of the Size and Shape of Self-Assembled Virus-Derived Particles (2013)

Controlling the geometry of self-assembly will enable a greater diversity of nanoparticles than now available. Viral capsid proteins, one starting point for investigating self-assembly, have evolved to form regular particles. The polyomavirus SV40 assembles from pentameric subunits and can encapsidate anionic cargos. On short ssRNA (≤814 nt), SV40 pentamers form 22 nm diameter capsids. On RNA too long to fit a T = 1 particle, pentamers forms strings of 22 nm particles and heterogeneous particles of 29-40 nm diameter. However, on dsDNA SV40 forms 50 nm particles composed of 72 pentamers. A 7.2-Å resolution cryo-EM image reconstruction of 22 nm particles shows that they are built of 12 pentamers arranged with T = 1 icosahedral symmetry. At 3-fold vertices, pentamers each contribute to a three-helix triangle. This geometry of interaction is not seen in crystal structures of T = 7 viruses and provides a structural basis for the smaller capsids. We propose that the heterogeneous particles are actually mosaics formed by combining different geometries of interaction from T = 1 capsids and virions. Assembly can be trapped in novel conformations because SV40 interpentamer contacts are relatively strong. The implication is that by virtue of their large catalog of interactions, SV40 pentamers have the ability to self-assemble on and conform to a broad range of shapes.
Assessment of DNA Damage at the Dimer Level: Measurement of the Formamide Lesion (2007)

UVC-radiation-induced DNA damage was measured in mouse fibroblast cells using liquid chromatography-tandem mass spectrometry (LC-MS/MS) in conjunction with isotopically labeled internal standards. The thymine glycol and formamide lesions were assayed in the form of modified dinucleoside monophosphates. The 8-oxo-7,8-dihydroguanine lesion was measured as the modified nucleoside. DNA damage in cells treated with tirapazamine was also measured. Tirapazamine is a chemotherapeutic agent that acts via a free radical mechanism. The two agents, UVC radiation and tirapazamine, produce markedly different profiles of DNA damage, reflecting their respective mechanisms of action. Both agents produce significant amounts of thymine glycol and formamide damage, but only the former produced a measurable amount of the 8-oxo-7,8-dihydroguanine lesion. The merits of measuring DNA damage at the dimer level are discussed.
Energy band structure and electrical properties of Ga-oxide/GaN interface formed by remote oxygen plasma (2018)

The energy band structure of a Ga-oxide/GaN structure formed by remote oxygen plasma exposure and the electrical interface properties of the GaN metal–oxide–semiconductor (MOS) capacitors with the SiO2/Ga-oxide/GaN structures with postdeposition annealing (PDA) at various temperatures have been investigated. Reflection high-energy electron diffraction and X-ray photoelectron spectroscopy clarified that the formed Ga-oxide layer is neither a single nor polycrystalline phase with high crystallinity. We found that the energy band offsets at the conduction band minimum and at the valence band maximum between the Ga-oxide layer and the GaN surface were 0.4 and 1.2 ± 0.2 eV, respectively. Furthermore, capacitance–voltage (C–V) characteristics revealed that the interface trap density (Dit) is lower than the evaluation limit of Terman method without depending on the PDA temperatures, and that the SiO2/Ga-oxide stack can work as a protection layer to maintain the low Dit, avoiding the significant decomposition of GaN at the high PDA temperature of 800 °C.
Fluorophore from citric acid and 1,2- ethylenediamine: synthesis and structure research (2020)

In this article, we have demonstrated the promising separation methods for hydrothermally obtained fluorescent molecule formed from citric acid and 1,2 – ethylenediamine. This fluorophore is a derivative of citrazinic acid and is known as a 1,2,3,5-tetrahydro-5-oxo-imidazo[1,2-a]pyridine-7-carboxylic acid (IPCA). Gel electrophoresis and dialysis were applied for the extraction the fluorophore from start materials. IPCA molecule has strong absorption at 350 nm and luminescence at 450 nm with a high quantum yield of around 85&plusmn;5%. The structure of the fluorophore and polymer-like structures was researched by spectrophotometry, spectrofluorimetry, IR and NMR spectroscopy.
The effect of plateletpheresis on the fenwal CS‐3000 on donor platelet counts (1987)

To evaluate the risk of significant plateletpheresis-induced thrombocytopenia in normal volunteer donors undergoing plateletpheresis less frequently than every 56 days and to help understand factors influencing platelet yield in these donors, pre- and postapheresis platelet counts (X 10(3)/microliter) and platelet yields were analyzed from 916 plateletpheresis procedures (Fenwal CS-3000) on 607 donors (405 men, 202 women). The mean preapheresis platelet count was 265 +/- 59 (SD) (range 155-650) (men 256 +/- 55 [170-444]; women 284 +/- 65 [155-650]; P less than .001, t-test). After an average platelet yield of 4.08 X 10(11), the mean postplatelet count was 185 +/- 46 (range 72-420) (men 184 +/- 42 [80-345]; women 194 +/- 52 [72-500]; P less than 0.1). The percent decrease in platelet count (mean 29.4 +/- 13, range -28.1-65.5) had positive correlations with platelet yield (P less than .01, r = 0.10), predonation platelet count (P less than .001, r = 0.29), and age (P less than .01, r = .10) and a negative correlation with weight (P less than .001, r = 0.18) Both the percent decrease and platelet yield were significantly higher in women than in men (P less than .001, t-test), and platelet yield was best predicted by preapheresis platelet count in both sexes (r = 0.65). The effects of plateletpheresis on donor platelet count thus vary widely among donors. Although a decrease of greater than 50% was not a rare event (5.9% of all procedures), in only three instances (0.3%) was the actual postapheresis platelet count below 100 (72, 94, 95). Thus, plateletpheresis in normal donors appears unlikely to produce clinically significant thrombocytopenia immediately after apheresis.
Studies on the syntheses of heterocyclic compounds. Part DCLV.. Two stereoisomers of 1‐benzyl‐5‐hydroxy‐6‐(4‐methoxybenzyl)‐4,5‐dimethylpiperidin‐2‐one (1976)

Abstract The stereochemistry of two diastereoisomers of 1‐benzyl‐5‐hydroxy‐6‐(4‐methoxybenzyl)‐4,5‐dimethylpiperidin‐2‐one (IV), which is an intermediate for synthesis of pentazocine (I), was elucidated.
An Ab initio comparative study of bicyclo[1.1.0]tetrasilane and bicyclo[2.2.0]hexasilane (1988)

Ab initio calculations show that bicyclo[2.2.0]hexasilane has a normal central bond, unlike the more strained bicyclo[1.1.0]tetrasilane, and is much less strained than its carbon analogue bicyclo[2.2.0]hexane.
Subclinical Longitudinal Change in Ankle‐Brachial Index With Aging in a Community‐Dwelling Population Is Associated With Central Arterial Stiffening (2019)

Background Aging is associated with a modest decline in ankle-brachial index (ABI); however, the underpinnings of this decline are not fully understood. The greater systolic ankle than brachial blood pressure, a normal ABI implies, is partially attributed to lower central than peripheral arterial stiffness. Hence, we examined the hypothesis that the age-associated decline in ABI is associated with central arterial stiffening with aging, assessed by pulse wave velocity. Methods and Results We analyzed longitudinal data from 974 participants aged 27 to 95 years from the Baltimore Longitudinal Study of Aging who were free of clinically significant cardiovascular disease. Participants had an average of 4 visits with a 6.8-year average follow-up time. Linear mixed-effects models showed that the average ABI decline beyond the age of 70 years was 0.03 per decade. In multiple regression analysis, the ABI rate of change was inversely associated with initial age (standardized β=-0.0711, P=0.0282), independent of peripheral disease factors and baseline ABI. After adjustment, the pulse wave velocity rate of change was inversely associated with ABI rate of change (standardized β=-0.0993, P=0.0040), rendering the association of the latter with initial age nonsignificant (standardized β=-0.0265, P=0.5418). Conclusions A modest longitudinal decline in ABI beyond the age of 70 years was shown to be independent of traditional risk factors for peripheral arterial disease but was accounted for by an increase in pulse wave velocity. A modest decline in ABI with aging might be a manifestation of changes in central hemodynamics and not necessarily attributable to peripheral flow-limiting factors.
Identification of 19-Hydroxydeoxycorticosterone, 19-Oxo-Deoxycorticosterone, and 19-Oic-Deoxycorticosterone as Products of Deoxycorticosterone Metabolism by Rat Adrenals* (1982)

The formation of 19-hydroxydeoxycorticosterone (19,21-dihydroxy-4-pregnen-3,20-dione), 19-oxo-deoxycorticosterone (21-hydroxy-4-pregnen-3,19,20-trione), and 19-oic-deoxycorticosterone (19-oic-21-hydroxy-4-pregnen-3,20-dione) from precursor deoxycorticosterone by adrenal glands obtained from intact rats and from rats undergoing adrenal regeneration was demonstrated. These metabolites were isopolar with corresponding authentic steroid standards on thin layer chromatography, gas chromatography, and high pressure liquid chromatography. They were further characterized by either mass spectrometry or gas chromatography-mass spectrometry. Therefore, rat adrenals have the enzymes required to convert deoxycorticosterone to 19-hydroxydeoxycorticosterone, 19-oxo-deoxycorticosterone, and 19-oic-deoxycorticosterone; however, rat adrenals do not convert deoxycorticosterone or any of the oxygenated metabolites to 19-nor-deoxycorticosterone (21-hydroxy-19-nor-4-pregnen-3,20-dione). It is possible, however, that 19-nor-deoxycorticosterone is formed at peripheral sites from the oxygenated deoxycorticosterone precursors.
Restricted structural gene polymorphism in the Mycobacterium tuberculosis complex indicates evolutionarily recent global dissemination (1997)

One-third of humans are infected with Mycobacterium tuberculosis, the causative agent of tuberculosis. Sequence analysis of two megabases in 26 structural genes or loci in strains recovered globally discovered a striking reduction of silent nucleotide substitutions compared with other human bacterial pathogens. The lack of neutral mutations in structural genes indicates that M. tuberculosis is evolutionarily young and has recently spread globally. Species diversity is largely caused by rapidly evolving insertion sequences, which means that mobile element movement is a fundamental process generating genomic variation in this pathogen. Three genetic groups of M. tuberculosis were identified based on two polymorphisms that occur at high frequency in the genes encoding catalase-peroxidase and the A subunit of gyrase. Group 1 organisms are evolutionarily old and allied with M. bovis, the cause of bovine tuberculosis. A subset of several distinct insertion sequence IS6110 subtypes of this genetic group have IS6110 integrated at the identical chromosomal insertion site, located between dnaA and dnaN in the region containing the origin of replication. Remarkably, study of approximately 6,000 isolates from patients in Houston and the New York City area discovered that 47 of 48 relatively large case clusters were caused by genotypic group 1 and 2 but not group 3 organisms. The observation that the newly emergent group 3 organisms are associated with sporadic rather than clustered cases suggests that the pathogen is evolving toward a state of reduced transmissability or virulence.
Personal atmospheric gas sampler using the critical orifice concept (1976)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPersonal atmospheric gas sampler using the critical orifice conceptFrederick W. Williams, Jack P. Stone, and Harold G. EatonCite this: Anal. Chem. 1976, 48, 2, 442–445Publication Date (Print):February 1, 1976Publication History Published online1 May 2002Published inissue 1 February 1976https://pubs.acs.org/doi/10.1021/ac60366a044https://doi.org/10.1021/ac60366a044research-articleACS PublicationsRequest reuse permissionsArticle Views45Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
An intrinsic beam model based on a helicoidal approximation—Part I: Formulation (1994)

Abstract The focus of the present work is directed towards the one‐dimensional non‐linear analysis of space‐curved and twisted beams undergoing large displacements and finite rotations. According to Cosserat's model, a beam is intended here as a continuum generated by the rigid motion of a cross‐section along a curve. The novelty of the proposed methodology is implied in the assumption that the reference line of the beam, both in the undeformed and in the deformed configurations, is a helicoid in space. This formulation radically departs from the classical beam models based on polynomial interpolations of the independent fields. In fact, within the framework of helicoidal geometry, a powerful description of space‐curved beam kinematics with large displacements and finite rotations can be developed. Furthermore, the beam model developed herein can be proved to enjoy several invariance properties that make it particularly attractive for non‐linear analysis. The formulation discussed in this work adheres to a mixed variational principle, the independent fields being the generalized displacements and the sectional stress resultants. In a companion paper, we address the linearization of the governing weak form, the finite element implementation of the proposed methodology with a novel incremental treatment of finite rotations, and the development of a helicoidal model for rigid body dynamics using finite elements in time.
Über 1, 2‐Dithiacyclopentene. XXV. 5‐Alkylmercapto‐1, 2‐dithiacyclopentenimine‐(3) und ihre Spaltung mit GRIGNARD‐Verbindungen (1973)

Abstract Ausgehend von 5‐Chlor‐1, 2‐dithiacyclopentenonen 1 werden 5‐Alkylmercapto‐3‐arylimino‐1, 2‐dithiacyclopentene 9 mit Chlor oder Aryl in 4‐Stellung synthetisiert. 5‐Methylmercapto‐3‐arylimino‐4‐aryl‐1, 2‐dithiacyclopentene reagieren mit Grignard ‐Verbindungen unter Spaltung der Disulfid‐Brücke.
Infective endocarditis on mitral annular calcification complicated with purulent pericarditis: A case report. (2017)

can be a rare predisposing factor for infective endocarditis (IE). The surgical treatment strategy for such cases remains uncertain. Case presentation: Methicillin-resistant Staphylococcus aureus (MRSA) IE complicated with purulent pericarditis and ventricular septal abscess was diagnosed in an 81-year-old woman with no significant past medical history. The patient underwent surgical treatment in two stages. The first operation consisted of purulent effusion drainage and pedicled omental flap implantation. The second operation, involving mitral vegetation and ventricular septal abscess debridement, was performed 7 days after the first operation. During the admission, appropriate antibiotic therapy was continued. Within a week after the last surgery, patient status (inflammatory markers, fever, and respiratory function) improved remarkably. However, the IE recurred and the patient finally died of sepsis and acute heart failure due to severe mitral regurgitation on postoperative day 37. This report describes a rare case of IE on MAC due to MRSA, complicated with purulent pericarditis caused by extracardiac invasion. Conclusions: Depending on clinical state of the patients, if annular invasion is suspected and MAC is detected in patients with IE, aggressive debridement and reconstruction of mitral annulus and septum might be necessary for such cases.
Temperature-Dependent Induction of Salicylic Acid and Its Conjugates during the Resistance Response to Tobacco Mosaic Virus Infection. (1992)

Increases in endogenous salicylic acid (SA) levels and induction of several families of pathogenesis-related genes (PR-1 through PR-5) occur during the resistance response of tobacco to tobacco mosaic virus infection. We found that at temperatures that prevent the induction of PR genes and resistance, the increases in SA levels were eliminated. The addition of exogenous SA to infected plants at these temperatures was sufficient to induce the PR genes but not the hypersensitive response. However, when the resistance response was restored by shifting infected plants to permissive temperatures, SA levels increased dramatically and preceded PR-1 gene expression and necrotic lesion formation associated with resistance. SA was also found in a conjugated form whose levels increased in parallel with the free SA levels. The majority of the conjugates appeared to be SA glucosides. The same glucoside was formed when plants were supplied with exogenous SA. These results provide further evidence that endogenous SA signals the induction of certain defense responses and suggests additional complexity in the modulation of this signal.