gebhart/patrepeval huggingface dataset:
Emscripten (2011)

We present Emscripten, a compiler from LLVM (Low Level Virtual Machine) assembly to JavaScript. This opens up two avenues for running code written in languages other than JavaScript on the web: (1) Compile code directly into LLVM assembly, and then compile that into JavaScript using Emscripten, or (2) Compile a language's entire runtime into LLVM and then JavaScript, as in the previous approach, and then use the compiled runtime to run code written in that language. For example, the former approach can work for C and C++, while the latter can work for Python; all three examples open up new opportunities for running code on the web.
Acoustic noise in induction motors: causes and solutions (2002)

This paper deals with the causes of acoustic noise in induction motors and presents methods to reduce the noise before and after the motor is manufactured. The acoustic noise in induction motors has three main sources: the first one is the ventilating system which is responsible for the noise level of 2 and 4 pole-motors due to the fan speed. The second is the magnetic noise, generated by vibration of the core due to the electromagnetic forces in the airgap. The third is the noise generated by the bearings. The influence of the PWM frequency inverters on the magnetic noise is also considered and results of tests performed on motors are also presented. It is shown that a reduction in the fan diameter decreases the noise emitted by the ventilating system. Related to the magnetic noise, solutions have been adopted during design stage by stator/rotor slot design. Finally, the paper presents advantages, disadvantages and general comments about each solution and comparing noise level with parameters described in standards.
Mycotherapy of Cancer: An Update on Cytotoxic and Antitumor Activities of Mushrooms, Bioactive Principles and Molecular Mechanisms of their Action (2013)

Mycotherapy is defined as the study of the use of extracts and compounds obtained from mushrooms as medicines or health-promoting agents. The present review updates the recent findings on anticancer/antitumor agents derived from mushroom extracts and their metabolites. The increasing number of studies in the past few years revealed mushroom extracts as potent antitumor agents. Also, numerous studies were conducted on bioactive compounds isolated from mushrooms reporting the heteropolysaccharides, β-glucans, α-glucans, proteins, complexes of polysaccharides with proteins, fatty acids, nucleoside antagonists, terpenoids, sesquiterpenes, lanostanoids, sterols and phenolic acids as promising antitumor agents. Also, molecular mechanisms of cytotoxicity against different cancer cell lines are discussed in this review. Findings with Antrodia camphorata and Ganoderma lucidium extracts and isolated compounds are presented, as being the most deeply studied previously.
Epidermal Growth Factor And Gastrin Combination Therapy Stimulates In Vivo Neogenesis Of Human Islet ∃-CELLS AND AN INCREASE IN FUNCTIONAL ∃-CELL MASS (2003)

SUAREZ-PINZON, W. L.; LAKEY, J. R.T.; POWER, R. F.; BRAND, S. J.; RAJOTTE, R. V; RABINOVITCH, A. Author Information
Castleman’s Disease and Posttransplant Lymphoproliferative Disorder after Liver Transplant: 3-Year Follow-Up (2018)

A 59-year-old male with a history of hepatitis C cirrhosis and history of hepatitis B exposure presented 8 months after orthotopic liver transplant (LT) with fever, fatigue, myalgia, night sweats, nonproductive cough, and shortness of breath. Bone marrow biopsy for pancytopenia was positive for Epstein-Barr virus (EBV) DNA. Lymph node biopsy for lymphadenopathy on imaging showed human herpes virus 8 (HHV8) associated Castleman's disease. Treatment included valganciclovir, rituximab, and prednisone taper with eventual discontinuation. Quantitative HHV8 DNA was initially 611,000 DNA copies/mL and was later undetectable at 6 months following treatment and remained undetectable at 3-year follow-up.
Cost-effectiveness of treatments for COPD (2016)

Chronic obstructive pulmonary disease is a long-term debilitating illness caused by inflammation and tissue destruction, resulting in impaired airflow and inadequate oxygen availability during exercise. Inhalers acting on the nervous system that control the respiratory muscles are the main drug therapy used to treat COPD—often in combination to enhance their efficacy. Anti-inflammatory formulae are also used, but more likely with long-lasting bronchoinhalers.
Comparison of Pinus taeda L. wood property calibrations based on NIR spectra from the radial-longitudinal and radial-transverse faces of wooden strips (2005)

Abstract When a radial strip is cut from an increment core it can potentially be cut with two orientations: parallel to longitudinal tracheids, i.e., a radial-longitudinal (RL) strip (the orientation of SilviScan samples), or at an orientation of 90° to the tracheids, i.e., a radial-transverse (RT) strip. Both strips could be used for near-infrared (NIR) analysis, but it is unknown how calibrations based on RT-face NIR spectra compare with those based on RL-face NIR spectra. A total of 20 Pinus taeda L. (loblolly pine) RL strips were characterized in terms of air-dry density, microfibril angle (MFA), stiffness and several tracheid morphological characteristics. NIR spectra were collected in 10-mm increments from the RL and RT faces of matching strips and used to develop calibrations for each property. In general, RL-face NIR spectra gave calibrations that provided stronger relationships. Differences between the two sets of calibrations were small, indicating that either face could be used for NIR analysis.
Molecular and functional characterization of a CS1 (CRACC) splice variant expressed in human NK cells that does not contain immunoreceptor tyrosine‐based switch motifs (2004)

CS1 (CRACC, novel Ly9) is a novel member of the CD2 family expressed on natural killer (NK), T and stimulated B cells. Although the cytoplasmic domain of CS1 contains immunoreceptor tyrosine-based switch motifs (ITSM), which enables to recruite signaling lymphocyte activation molecule (SLAM)-associated protein (SAP/SH2D1A), it activates NK cells in the absence of a functional SAP. CS1 is a self ligand and homophilic interaction of CS1 regulates NK cell cytolytic activity. Here we have identified a novel splice variant of CS1 (CS1-S), which lacks ITSM. Human NK cells express mRNA for both wild-type CS1 (CS1-L) and CS1-S and their expression level remained steady upon various stimulations. To determine the function of each isoform, cDNA for CS1-L and CS1-S were transfected into the rat NK cell line RNK-16 and functionally tested using redirected cytotoxicity assays and calcium flux experiments. CS1-L was able to mediate redirected cytotoxicity of P815 target cells in the presence of monoclonal antibody against CS1 and a rise in intracellular calcium within RNK-16 cells, suggesting that CS1-L is an activating receptor, whereas CS1-S showed no effects. Interestingly, SAP associated with unstimulated CS1-L and dissociated upon pervanadate stimulation. These results indicate that CS1-L and CS1-S may differentially regulate human NK cell functions.
An empirical evaluation of supervised learning in high dimensions (2008)

In this paper we perform an empirical evaluation of supervised learning on highdimensional data.We evaluate performance on three metrics: accuracy, AUC, and squared loss and study the effect of increasing dimensionality on the performance of the learning algorithms.Our findings are consistent with previous studies for problems of relatively low dimension, but suggest that as dimensionality increases the relative performance of the learning algorithms changes.To our surprise, the method that performs consistently well across all dimensions is random forests, followed by neural nets, boosted trees, and SVMs.
Implantable Electrode For Critical Locations (1990)

Implantable electrode holds itself in place until body tissue grows around it and retains it. Sheath covers electrode during implantation. Partially retracted after implantation and completely retracted after growth of tissue onto electrode. Intended to provide electrical stimuli to muscles having become inactive through accident or disease. Helps paraplegics and others to exercise voluntary control over arms and legs.
Heparin protects cathepsin G against inhibition by protein proteinase inhibitors. (1994)

Cathepsin G, a cationic serine proteinase present in neutrophils and monocytes, is able to cleave biologically important proteins and may thus participate in tissue destruction during inflammation. Its activity is physiologically controlled by the fast-acting serpins, alpha 1-anti-chymotrypsin (ka = 5 x 10(7) M-1 S-1) and alpha 1-proteinase inhibitor (ka = 2.7 x 10(5) M-1 S-1). We have shown that cathepsin G forms a tightly bound 1:1 complex with a 5-kDa heparin fragment (Kd = 1.9 x 10-8 M). The partial enzymatic activity retained by this complex is inhibited extremely slowly by the above 68- and 53-kDa serpins. The activity of the complex is also virtually resistant to inhibition by eglin c, and 8-kDa non-serpin inhibitor. A detailed kinetic investigation showed that the inhibition of heparin-bound cathepsin G by the three proteins proceeded via a two-step mechanism. [formula: see text] The three inhibitors have widely different Ki* values (0.18-13 microM) (Ki* = k-1/k1). Their isomerization constants k2 are, however, all in the same range and their extremely low values (0.7-3 ms-1) account for the very low rate of cathepsin G inhibition. The second-order inhibition rate constants k2/Ki* were 4300, 700, and 52 M-1 S-1 for alpha 1-antichymotrypsin, alpha 1-antitrypsin, and eglin c, respectively, indicating that, if heparin is present in vivo, the two former physiological inhibitors will be unable to prevent cathepsin G-mediated proteolysis. Neutrophil elastase binds the 5-kDa heparin fragment with an affinity identical to that of cathepsin G. alpha 1-Proteinase inhibitor reacts, however, much faster with heparin-elastase (ka = 1.8 x 10(6) M-1 S-1) than with heparin-cathepsin G (k2/Ki* = 700 M-1 S-1).
[A remarkable effect of alpha-interferon in a case of angioimmunoblastic lymphadenopathy with dysproteinaemia (AILD) refractory to steroids and combination chemotherapies]. (1991)

We experienced a remarkable effect of recombinant interferon alpha 2a (alpha-IFN) in a case of angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) which was refractory to steroids and combination chemotherapies. A 62 year-old woman was admitted because of high grade fever and extreme swelling of cervical lymph nodes. Poly-clonal hypergammaglobulinemia and plasma cell-like atypical lymphocytosis in the peripheral blood were demonstrated. Cervical lymph node biopsy disclosed histology of AILD. She initially responded well to prednisolone. Three months later, AILD relapsed in spite of prednisolone treatment. She received combination chemotherapies and responded well again. Seven months later, she became refractory to these combination chemotherapies. Consequently, we tried alpha-IFN (3 million units/day given intramuscularly). She became afebrile on the next day, and lymph nodes swelling gradually disappeared. She has been free from the disease for more than three months.
Blind recognition of OFDM signals based on cyclostationary signal analysis (2017)

Growth in telecommunication world leads to an increase in the importance of efficient usage of frequency spectrum. Increasing number of subscribers and their demands force network operators to use the frequency bands as efficiently as possible. It is necessary to detect and prevent the interference of secondary or unauthorized frequency band occupations. Cyclostationary signal analysis is widely used for detection of interference signals. In this paper, cyclostationary characteristics have been derived for OFDM signals. The associated spectral correlation density function has been computed by using FFT accumulation method. This analysis can be used for blind recognition of OFDM based interference signals in presence of other interference sources.
TCP alternate checksum options (1990)

This memo is suggests a pair of TCP options to allow use of alternate
data checksum algorithms in the TCP header. The use of these options
is experimental, and not recommended for production use. Note: This
RFC corrects errors introduced in the editing process in RFC 1145.
Resilient operation of transportation networks via variable speed limits (2017)

In this paper, we investigate the use of variable speed limits for resilient operation of transportation networks, which are modeled as dynamical flow networks under local routing decisions. In such systems, some external inflow is injected to the so-called origin nodes of the network. The total inflow arriving at each node is routed to its operational outgoing links based on their current particle densities. The density on each link has first order dynamics driven by the difference of its incoming and outgoing flows. A link irreversibly fails if it reaches its jam density. Such failures may propagate in the network and cause a systemic failure. We show that larger link capacities do not necessarily help in preventing systemic failures under local routing. Accordingly, we propose the use of variable speed limits to operate the links below their capacities, when necessary, to compensate for the lack of global information and coordination in routing decisions. Our main result shows that systemic failures under feasible external inflows can always be averted through a proper selection of speed limits if the routing decisions are sufficiently responsive to local congestion and the network is initially uncongested. This is an attractive feature as it is much easier in practice to adjust the speed limits than to build more physical capacity or to alter routing decisions that are determined by social behavior.
Derepression of Glycine Decarboxylase Synthesis by Magnesium Phosphate inNocardia butanica (1981)

Journal Article Derepression of Glycine Decarboxylase Synthesis by Magnesium Phosphate in Nocardia butanica Get access Yoshitake Tanaka, Yoshitake Tanaka School of Pharmaceutical Sciences, Kitasato University and The Kitasato Institute, Minato-ku, Tokyo 108, Japan Search for other works by this author on: Oxford Academic Google Scholar Satoshi Ōmura, Satoshi Ōmura School of Pharmaceutical Sciences, Kitasato University and The Kitasato Institute, Minato-ku, Tokyo 108, Japan Search for other works by this author on: Oxford Academic Google Scholar Kazumi Araki, Kazumi Araki Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., Machida-shi, Tokyo 194, Japan Search for other works by this author on: Oxford Academic Google Scholar Kiyoshi Nakayama Kiyoshi Nakayama Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., Machida-shi, Tokyo 194, Japan Search for other works by this author on: Oxford Academic Google Scholar Agricultural and Biological Chemistry, Volume 45, Issue 11, 1 November 1981, Pages 2661–2664, https://doi.org/10.1080/00021369.1981.10864946 Published: 01 November 1981 Article history Received: 27 May 1981 Published: 01 November 1981
An Iterative Physical Optics (IPO) Approach for Scattering by Penetrable Surfaces (2021)

An iterative physical optics (IPO) algorithm for the analysis of scattering by penetrable acoustically large objects, composed of penetrable and opaque surfaces, is proposed. The scatterer surfaces are assumed in general to be non-convex and multiply connected, such that self-shadowing effects should be accounted for. This is done by extending the shadow radiation IPO (SR-IPO) scheme, developed for the case of impenetrable surface scatterers. For the penetrable surfaces case, the IPO scattering problem formulation is modified in order to make it compatible with the SR-IPO process. The key features of the formulation are discussed and a rudimentary validation of the formulation is presented for an acoustically representative example.
Differential Physiological Responses of Dalmatian Toadflax,Linaria dalmaticaL. Miller, to Injury from Two Insect Biological Control Agents: Implications for Decision-Making in Biological Control (2005)

Successful biological control of invasive weeds with specialist herbivorous insects is predicated on the assumption that the injury stresses the weeds sufficiently to cause reductions in individual fitness. Because plant gas exchange directly impacts growth and fitness, characterizing how injury affects these primary processes may provide a key indicator of physiological impairment—which then may lead to reductions in fitness. The objective of this study was to use physiological methods to evaluate how the invasive weed, Linaria dalmatica L. Miller (Dalmatian toadflax), is affected by two introduced biological control agents within different injury guilds: the stem-boring weevil, Mecinus janthinus Germar, and the defoliating moth, Calophasia lunula Hufnagel. All studies with M. janthinus were conducted under field conditions at two sites in Montana in 2003 and 2004. For C. lunula evaluations, a total of five greenhouse studies in 2003 and 2004 were used. One field study in 2003 and two studies in 2004 also were conducted. Variables measured included net CO2 exchange rate, stomatal conductance, and transpiration rate. Results from both field sites revealed that the primary physiology of Dalmatian toadflax was deleteriously affected by M. janthinus larval injury. There were no significant differences among treatments for any of the gas exchange variables measured in all eight experiments with C. lunula. Our results indicate that insect herbivores in two distinct injury guilds differentially affect Dalmatian toadflax physiology. Based on the primary physiological parameters evaluated in this study, M. janthinus had more impact on Dalmatian toadflax than C. lunula. With such information, improved risk-benefit decisions can be made about whether to release exotic biological control agents.
Enantioselective construction of C2-symmetric spiro skeleton through intramolecular copper-catalyzed N-arylation (2014)

Enantioselective construction of a C 2 -symmetric spirobi(1,2,3,4-tetrahydroquinoline) framework has been achieved through an intramolecular Cu-catalyzed C-N bond coupling of 1,3propanediamide substrates possessing bromophenyl substituents. The use of N,N'-dimethyl-1,2diphenylethylenediamine as the chiral ligand was found to be essential in this asymmetric catalysis. Optically pure compound was shortly obtained by a single recrystallization of the enantioenriched product, which was successfully derivatised to a new chiral diphosphine ligand.
Molecular design of host materials for high power efficiency in blue phosphorescent organic light-emitting diodes doped with an imidazole ligand based triplet emitter (2015)

Molecular design strategy to improve the power efficiency of blue phosphorescent organic light-emitting diodes was proposed by introducing a CN modified carbazole moiety.
On the Ultrasonic Atomization of Liquids (2015)

This paper deals with an experimental study of liquid atomization phenomena. For this study an experimental set-up was designed and constructed. A special criterion to start the recording of the process with a high speed digital camera was developed. The frequency dependence of atomization threshold is considered. The theoretical predictions for atomization threshold are also checked. The agreement between the predictions and the experimental results fit qualitatively with the data well until a frequency of 22 kHz. For frequencies beyond this value the tendencies are the opposite.
ChemInform Abstract: A Perspective to Resorcinarene Crowns (2014)

Abstract Review: [44 refs.
An enabling platform for autonomic management of the future internet (2011)

This article shows an autonomic management solution based on the recently defined programmable node architecture NetServ. The article starts with a general description of the classical network management requirements and their adaptation to the expected network evolution. After a description of the major issues characterizing the management of the expected Future Internet, the main autonomic management paradigms, and some recently introduced autonomic service platforms, we show and demonstrate the effectiveness of the NetServ architecture. Born as a means to deploy and execute networked services at runtime over programmable routers, NetServ has proved to be a suitable environment for hosting an autonomic management architecture.
An anatomical study of the buccinator muscle fibres that extend to the terminal portion of the parotid duct, and their functional roles in salivary secretion (2006)

Until now there has been no definitive anatomical study describing the area where the parotid duct enters the buccinator muscle. In this study, we performed anatomical and histological examinations to investigate the relationship between the parotid duct and the buccinator muscle. Thirty specimens (including the buccinator and the terminal portion of the parotid duct) were obtained from embalmed Korean cadavers. Dissection was performed on 22 of these specimens, and the remaining eight specimens were prepared for histological examination and stained with haematoxylin-eosin or Gomori trichrome. In all specimens, small, distinct muscle fibres originating from the buccinator muscle extended to and inserted into the terminal portion of the parotid duct. The topography of these fibres varied, and we classified them into three categories according to where they originated. Type I buccinator muscle fibres, which inserted into the terminal portion of the parotid duct, originated simultaneously from the anterior and posterior aspects of the duct (ten cases, 45.5%). Type II fibres originated from the anterior aspect of the duct and inserted into the anterior side of the duct (seven cases, 31.8%). Type III fibres originated from the posterior aspect of the parotid duct and ran anteriorly toward the duct (five cases, 22.7%). These results were confirmed in the histological examination of all eight specimens. Based on these findings, we have proposed a tentative description of the physiological role of the buccinator muscle fibres in salivary secretion and in the formation of the sialoliths.
Acetate-encapsulated Linolenic Acid Liposomes Reduce SARS-CoV-2 and RSV Infection (2023)

Emergent Coronaviridae viruses, such as SARS-CoV-1 in 2003, MERS-CoV in 2012, and SARS-CoV-2 (CoV-2) in 2019, have caused millions of deaths. These viruses have added to the existing respiratory infection burden along with respiratory syncytial virus (RSV) and influenza. There are limited therapies for respiratory viruses, with broad-spectrum treatment remaining an unmet need. Since gut fermentation of fiber produces short-chain fatty acids (SCFA) with antiviral potential, developing a fatty acid-based broad-spectrum antiviral was investigated. Molecular docking of fatty acids showed α-linolenic acid (ALA) is likely to interact with CoV-2-S, NL63-CoV-S, and RSV-F, and an ALA-containing liposome interacted with CoV-2 directly, degrading the particle. Furthermore, a combination of ALA and a SCFA-acetate synergistically inhibited CoV2-N expression and significantly reduced viral plaque formation and IL-6 and IL-1β transcript expression in Calu-3 cells, while increasing the expression of IFN-β. A similar effect was also observed in RSV-infected A549 cells. Moreover, mice infected with a murine-adapted SARS-CoV-2 (MA10) and treated with an ALA-liposome encapsulating acetate showed significant reductions in plaque-forming units present in lung tissue and in infection-associated lung inflammation and cytokines. Taken together, these results demonstrate that the ALA liposome-encapsulating acetate can be a promising broad antiviral therapy against respiratory infections.