gebhart/patrepeval huggingface dataset:
Automated antenna impedance adjustment for Near Field Communication (NFC) (2013)

Near Field Communication (NFC) is a very intuitive way to open a communication link, to authenticate, or to implement a payment by simply bringing two mobile personal devices closely together. NFC is based upon reliable contactless card technology and combines most prominent protocol standards in a specification driven by the NFC Forum. Devices with a NFC interface operate at 13.56 MHz via inductive loop antennas. However, these operate operated in a very different environment than contactless cards. Metal, the presence of several other antennas, and market demands for compact electronic devices are driving requirements for antennas to operate on ferrite foils, resulting in significant tolerances on antenna impedance. In NFC Reader mode, the antennas operate in a resonance circuit, making this de-tuning critical. This paper presents a prototype implementation for automated antenna impedance adjustment based upon Digitally Tunable Capacitors (DTCs). To show the benefit, the paper explains efficiency for contactless power transfer by practical measurements, comparing three scenarios-fixed impedance adjustment, matching with tolerance, and automated readjustment using a DTC.
Structural Design Concepts (Some NASA Contributions) (1967)

Abstract : As man pushes back the frontiers of high speed flight, changes in structural design requirements necessitate the development of new materials. During the last few years, material and structural engineers have solved many formidable problems in ways that have led to significant changes in the design process itself. They have been able to develop new materials and designs without sacrificing structural weight to gross operating weight ratios. In fact, these ratios are generally comparable to, or in many cases better than, those for slower vehicles. This new knowledge and experience are providing a firm foundation for the design of structures to meet individual as well as space requirements. This survey has three main aims: (1) to identify for those in the field of structural design the contributions of the National Aeronautics and Space Administration (NASA) and the programs it has sponsored; (2) to describe the development of construction materials associated with these advances; and (3) to suggest, by examples, some of the applications in which they may be used. The survey covers structural types (including material systems), structural concepts, and structural design synthesis and optimization. While the analyst may not find this approach as sophisticated as the designer will, lie may gain from it some insight into the development of new structural design concepts. The degree to which these and other developments ultimately are utilized commercially depends on the foresight and ingenuity of structural designers. Selection of materials and structural design to meet specific performance requirements is a complex problem. Each configuration and each part of the configuration must be examined and analyzed to provide the best possible structure for each application.
Data from Efficacy of IGFBP7 for treatment of metastatic melanoma and other cancers in mouse models and human cell lines (2023)

&lt;div&gt;Abstract&lt;p&gt;We recently identified the secreted protein IGFBP7 as a factor required for an activated &lt;i&gt;BRAF&lt;/i&gt; oncogene to induce senescence or apoptosis in primary human cells. In human melanomas containing an activating BRAF mutation (BRAF-positive melanomas), &lt;i&gt;IGFBP7&lt;/i&gt; is epigenetically silenced, which seems to be a critical step in melanoma genesis. Restoration of IGFBP7 function by the addition of recombinant IGFBP7 (rIGFBP7) induces apoptosis in BRAF-positive human melanoma cell lines, and systemically administered rIGFBP7 markedly suppresses the growth of BRAF-positive primary tumors in xenografted mice. Here we further evaluate the role of IGFBP7 in the treatment of BRAF-positive melanoma and other malignancies. We find that in human metastatic melanoma samples &lt;i&gt;IGFBP7&lt;/i&gt; is epigenetically silenced and at an even higher frequency than that found in primary melanomas. Using a murine experimental metastasis assay, we show that systemic administration of rIGFBP7 markedly suppresses the growth of metastatic disease and prolongs survival. An analysis of the NCI60 panel of human cancer cell lines reveals that in addition to melanoma, IGFBP7 induces apoptosis in several other cancer types, in particular colorectal cancer cell lines. In general, IGFBP7 induces apoptosis in human cancer cell lines that have an activating mutation in BRAF or RAS, and that are sensitive to chemical inhibition of BRAF-MEK-ERK signaling. Significantly, systemically administered rIGFBP7 blocks the growth of colorectal tumors containing an activating RAS or BRAF mutation in mouse xenografts. The results presented here, in conjunction with those from previous studies, justify the further development of IGFBP7 as an anticancer agent. [Mol Cancer Ther 2009;8(11):3009–14]&lt;/p&gt;&lt;/div&gt;
The research on the technique of microseismic data-monitoring compression (2014)

Welcome to the WIT Press eLibrary - the home of the Transactions of the Wessex Institute collection, providing on-line access to papers presented at the Institute's prestigious international conferences and from its State-of-the-Art in Science & Engineering publications.
Intravenous Perfluorocarbon After Onset of Decompression Sickness Decreases Mortality in 20-kg Swine (2010)

PFC administered after DCS onset improved survival in this 20-kg swine model. Further study into the mechanisms of benefit and delayed DCS therapy are warranted.
Gold‐ and Silver‐Catalyzed Intramolecular Cyclizations of Indolylcyclopropenes for the Divergent Synthesis of Azepinoindoles and Spiroindoline Piperidines (2015)

Abstract Gold‐ and silver‐catalyzed novel intramolecular cycloisomerizations of nitrogen or carbon‐tethered indolylcyclopropenes to furnish biologically and pharmaceutically valuable azepino‐[4,5‐ b ]indole and spiro[indoline‐3,4′‐piperidine] derivatives have been developed. Both reactions exhibit high chemoselectivity and stereospecificity through completely different reaction pathways. Based on mechanistic studies, it is well demonstrated that gold and silver catalysts act differently to promote the anti‐ and syn‐addition and the steric effect of the catalysts play an important role to switch the addition mode, affording the catalyst‐controlled‐divergent synthesis.
Effective Level Set Image Segmentation With a Kernel Induced Data Term (2009)

This study investigates level set multiphase image segmentation by kernel mapping and piecewise constant modeling of the image data thereof. A kernel function maps implicitly the original data into data of a higher dimension so that the piecewise constant model becomes applicable. This leads to a flexible and effective alternative to complex modeling of the image data. The method uses an active curve objective functional with two terms: an original term which evaluates the deviation of the mapped image data within each segmentation region from the piecewise constant model and a classic length regularization term for smooth region boundaries. Functional minimization is carried out by iterations of two consecutive steps: 1) minimization with respect to the segmentation by curve evolution via Euler-Lagrange descent equations and 2) minimization with respect to the regions parameters via fixed point iterations. Using a common kernel function, this step amounts to a mean shift parameter update. We verified the effectiveness of the method by a quantitative and comparative performance evaluation over a large number of experiments on synthetic images, as well as experiments with a variety of real images such as medical, satellite, and natural images, as well as motion maps.
Unchannelized dam-break flows: Effects of the lateral spreading on the flow dynamics (2013)

In this paper, we used a three-dimensional discrete-grain model (Grains3D) to explore the flow and deposit characteristics of unchannelized dam-break collapses. A series of numerical experiments was performed to predict the behaviour of different granular columns (characterized by different initial aspect ratio a, varying from 0.5 to 18). As observed previously in similar channelized dam-break flows and axisymmetric slumps, the phenomenology of the collapse depends strongly on a, revealing different flow regimes. Small collapsing heaps (a ≲ 3) develop shallow cascades that form deposits characterized by a tail extended by a rounded frontal region. Instead, tall avalanching columns (a ≳ 3) generate dense, fast-moving currents that form a circular final deposit that resembles to those obtained from axisymmetric columns. The conversion from vertical to horizontal momentum was observed to be more efficient in these flows. The aggrading inner tapering region of static grains developed during the flow increases the number of final cascades necessary to adjust the slope of the final deposit, extending the total flow duration from 3 τc in dam-break flows to 7 τc in unchannelized ones. Surprisingly, mean aggradation velocities measured at different locations were observed to be independent of the lateral position, depending primarily on the longitudinal distance from reservoir and the initial aspect ratio. Scaled deposit widths and runouts revealed different power-law dependences on a, exposing a non-isotropic behaviour which tends to form a smooth transition from channelized dam-break flows to axisymmetric slumps.
Control Testing and Effect of Manufacturing Parameters on the Biocompatibility of Polypropylene Mesh Implants (2017)

This chapter discusses the effect of manufacturing parameters on the stability of the polypropylene (PP) mesh. Moreover, it sheds light on significant quality control tests that need to be considered for polymeric implants. PP mesh has been widely used as a permanent implant to repair hernia and to augment the vaginal wall for patients with urination incontinence. The biocompatibility of the mesh device is determined by the microstructure of PP that induces chemical inertness at the interface with the biological system. Processing parameters such as temperature, mechanical stresses, and environmental conditions can affect the microstructure, chemical stability, and hence the biocompatibility of PP. The interrelationship among processing, structure, and properties is explained by materials-science triad. The processing condition of the polypropylene mesh resulted in the alteration of the microstructure, deterioration of the crystalline phase, and oxidative degradation of polypropylene fibers as confirmed by fourier transform infrared spectrometry (FTIR), differential scanning calorimetry (DSC), scanning electron microscopy (SEM) analyses of pristine fibers.
Temperature and structure size dependence of the thermal conductivity of porous silicon (2011)

In order to assess the potential of porous Si as thermoelectric material we have performed thermal conductivity measurements in dependence of both temperature and average structure size. Investigations on samples with average structure sizes between 7 nm and 100 nm reveal a pronounced reduction in thermal conductivity which is encouraging for the future use of porous Si as thermoelectric material. The observed dependence on structure size and temperature can be explained in terms of a simple kinetic model based on the reduction of the effective phonon mean free path.
Production of antibody against aflatoxin B1 (1977)

Antibody against aflatoxin B1 was obtained after one multiple-site injection of bovine serum albumin-aflatoxin B1 conjugate into rabbits. The antibody has greatest binding efficiency for aflatoxin B1, less efficiency for B2, G1, and Q1, and least for aflatoxicol, G2, and M1. Sterigmatocystin, coumarin, and 4-hydroxycoumarin did not give a cross-reaction with the antibody. The sensitivity of the binding assay for detection of aflatoxin B1 is in the range of 0.2 to 2.0 ng per 0.5-ml sample. Detailed methods for the preparation of the conjugate, production of immune serum, and methods for antibody titer determination are described.
Contemporary oral and maxillofacial surgery. (1994)

This article provides a panoramic view of the nine major areas of subspecialty in the field of oral and maxillofacial surgery: facial trauma, surgical pathology, dentoalveolar surgery, rehabilitation of the cleft lip/palate patient, temporomandibular joint surgery, preprosthetic and implant rehabilitation, surgical management of obstructive sleep apnea, correction of jaw deformities and cosmetic+ surgery. Clinical cases are used to illustrate the most recent advances in each of these nine areas.
Direct 880 nm diode-pumping of vanadate lasers (2003)

Summary from only given. We have demonstrated, what we believe is for the first time, direct diode-pumping of end-pumped vanadate lasers such as Nd:YVO/sub 4/ lasers. Scaling to TEM/sub 00/ mode powers in excess of 20 W is currently being investigated. Results for higher pump powers and for dual end-pumping will be presented.
Optical diagnostics investigation of wake flow fields behind geometrically modified turrets (2012)

An experimental investigation was conducted on the ow elds behind various hemisphereon-cylinder turret geometries in subsonic ow. The e ects that geometric modi cations had on the baseline ow eld were characterized to determine which designs, if any, demonstrate potential as passive ow control mechanisms. Qualitative results were obtained for each turret model using a pulse burst laser to perform three-dimensional ow visualization. Additional, quantitative measurements along the wake centerline for each design were made via planar particle image velocimetry (PIV). The results of each modi ed ow eld are presented with the baseline case for comparison. Suggested future work is also given for those designs showing the most promise as passive ow control devices.
Results of a Randomized Phase III Trial of Mirabegron in Patients with Overactive Bladder (2012)

Once daily mirabegron in a 50 or 100 mg dose is an effective treatment for overactive bladder symptoms with a low occurrence of side effects.
Selective atomic layer deposition of HfO2 on copper patterned silicon substrates (2010)

Selective atomic layer deposition (ALD) was performed on copper patterned silicon substrates to selectively deposit HfO2 film on silicon. The selectivity is based on differences of surface physics/chemistry rather than use of any molecular masking such as self-assembled monolayers. On silicon, the growth rate of HfO2 is 0.11 nm /cycle with no initial inhibition of film growth, while on copper no HfO2 deposition was observed up to at least 25 ALD cycles. The selective growth on silicon over copper at 25 ALD cycles provides a patterned film deposition at thicknesses of 2.8 nm HfO2 which is relevant to semiconductor nanofabrication.
Arthroscopic microdiscectomy (1992)

Follow-up examinations performed a minimum of 2 years postoperatively showed that no neurovascular complications developed in 100 patients who underwent arthroscopic microdiscectomy for treatment of herniated discs at L3-4, L4-5, or L5-S1. By using a posterolateral approach, endoscopic control, and specially designed straight, upbiting, and deflectable forceps, it was possible to remove not only fragments located in the center of the nucleus, but also fragments that had migrated posteriorly and posterolaterally. Analysis of operative results by a modification of the Rush-Presbyterian-St. Luke's lumbar spine analysis system demonstrated that 88 of the patients attained excellent or good results and 12 attained poor or fair results. The outcome of surgery was not related to age, sex, or surgical level. The most common causes of an unsuccessful surgical outcome were lateral recess stenosis and sequestered fragments missed in the preoperative work-up.
PPAR Gamma Agonist Leriglitazone Recovers Alterations Due to Pank2-Deficiency in hiPS-Derived Astrocytes (2023)

The novel brain-penetrant peroxisome proliferator-activated receptor gamma agonist leriglitazone, previously validated for other rare neurodegenerative diseases, is a small molecule that acts as a regulator of mitochondrial function and exerts neuroprotective, anti-oxidative and anti-inflammatory effects. Herein, we tested whether leriglitazone can be effective in ameliorating the mitochondrial defects that characterize an hiPS-derived model of Pantothenate kinase-2 associated Neurodegeneration (PKAN). PKAN is caused by a genetic alteration in the mitochondrial enzyme pantothenate kinase-2, whose function is to catalyze the first reaction of the CoA biosynthetic pathway, and for which no effective cure is available. The PKAN hiPS-derived astrocytes are characterized by mitochondrial dysfunction, cytosolic iron deposition, oxidative stress and neurotoxicity. We monitored the effect of leriglitazone in comparison with CoA on hiPS-derived astrocytes from three healthy subjects and three PKAN patients. The treatment with leriglitazone did not affect the differentiation of the neuronal precursor cells into astrocytes, and it improved the viability of PKAN cells and their respiratory activity, while diminishing the iron accumulation similarly or even better than CoA. The data suggest that leriglitazone is well tolerated in this cellular model and could be considered a beneficial therapeutic approach in the treatment of PKAN.
Specificity of tumor antigen recognition by T-lymphocytes in the leukocyte adherence inhibition (LAI) assay in patients with breast cancer. (1982)

In an attempt to enhance the specificity with LAI assay in the diagnosis of cancer, we explored the possibility of using highly purified, 51Cr-prelabeled-PBL-subpopulations in performance of the assay. Leukocyte separation was achieved in 2 stages which involved EAET rosetting for the isolation of T-lymphocytes followed by Percoll gradient for separation of monocytes. These procedures provided excellent cellular yield, viability and cellular enrichment. By comparing the reactivity of various isolated subpopulations from breast cancer patients we established the critical role of T-lymphocytes in the recognition of tumor antigen in the LAI reaction, i.e. T-lymphocytes exhibited a breast cancer extract-specific response, reflected in a significant reduction of leukocyte adherence, while B-lymphocytes did not respond. In contrast, monocytes of breast cancer patients showed a non-specific LAI response to several unrelated tumor extracts. Similarly, T-lymphocytes from all patients with benign breast diseases as well as from healthy subjects showed no LAI response while false positive responses were detected in the unseparated PBL and monocytes of these individuals. It is concluded, therefore, that a differential diagnosis of cancer can only be made if isolated T-lymphocytes from PBL are used in the LAI assay procedure.
Link adaptation for real-time video communications in E-GPRS networks (2004)

The authors investigate deployment of link adaptation techniques to enhance the performance of real-time video communications over time-varying error-prone environments. A novel link adaptation algorithm is proposed and analysed. Two approaches for link adaptation are investigated. The first approach aims to optimise video quality for a fixed channel allocation. The design criterion of the second approach is to maximise the overall access network throughput while maintaining the required video quality. The effectiveness of the algorithms is demonstrated for MPEG-4 coded video transmissions over simulated EGPRS networks. In addition, the effects of feedback delay, a noisy feedback channel and bursty channel errors on algorithm performance are investigated.
Young African American women’s participation in an m-Health study in cardiovascular risk reduction: Feasibility, benefits, and barriers (2019)

The m-Health intervention was feasible as a means of cardiovascular disease risk reduction for young black women. In addition, we found that targeting women provided indirect benefits for other family members, especially children. Most of the participants did not encounter systemic barriers to participation, suggesting that mobile health interventions can be effective tools to improve health behaviors in vulnerable populations.
OEM 21.5 Elevator Advertising Player Digital Signage for Wholesaler (2009)

The usefulness of a new rapid diagnostic test (Patho-TB) using antibodies specific to mycobacterial antigens was evaluated for the rapid discrimination between pulmonary tuberculosis (TB) and non-TB pulmonary diseases on sputa. One hundred sputa collected from 79 active TB patients and from 21 patients with non-TB pulmonary diseases (asthma and chronic obstructive pulmonary disease) were enrolled into the study and tested for the presence of Mycobacterium tuberculosis by Ziehl-Neelsen smear, Patho-TB kit, and Lowenstein-Jensen culture. The sensitivity, specificity, positive predictive value, and negative predictive value of the Patho-TB test were 95%, 100%, 100%, and 84%, respectively. Patho-TB test is simple, quick, and easy to perform. Its sensitivity, specificity, and positive predictive value are satisfactory. Therefore, it could be used as a screening test in poorly equipped laboratories of TB endemic areas.
Cardiac output and peripheral resistance during larval development in the anuran amphibian Xenopus laevis (1995)

Stroke volume (SV) and cardiac output (CO) were measured in anesthetized larvae of Xenopus laevis from hatching (3 mg) to the end of metamorphosis (approximately 1 g). CO and SV were calculated from videotaped images of the intact beating heart. SV increased from 2.4 x 10(-3) microliters at 3 mg body mass to 7.6 microliters at 1 g. CO increased from 0.25 microliter/min at 3 mg to 623 microliters/min at 1 g. With use of CO, along with arterial pressures from another study [P.-C. L. Hou and W. W. Burggren. Am. J. Physiol. 269 (Regulatory Integrative Comp. Physiol. 38): R1120-R1125, 1995], peripheral resistance and cardiac work were also calculated. Resistance decreased rapidly from 701 peripheral resistance units (PRU, mmHg.s.mm-3) at 3 mg body mass to 79 PRU at 20 mg and gradually declined toward 0.9 PRU at 1 g. Cardiac work increased from 0.06 dyn.mm at 3 mg body mass to 1.27 dyn.mm at 20 mg and then climbed sharply to 717 dyn.mm at 1 g. The general pattern of change in hemodynamic variables (except heart rate) during larval development is similar in Xenopus laevis and chick embryos, suggesting a common pattern for hemodynamic development in vertebrate embryos/larvae.
Analysis of spinocerebellar ataxia type 2 gene and haplotype analysis: (CCG)1-2 polymorphism and contribution to founder effect. (1999)

Spinocerebellar ataxia type 2 is a familial spinocerebellar ataxia with autosomal dominant inheritance. The gene responsible was recently cloned and this disorder was found to be the result of a CAG expansion in its open reading frame. We analysed 13 SCA2 patients in seven unrelated families in Gunma Prefecture, Japan. In four of the seven families, we detected CCG or CCGCCG interruptions in only the expanded alleles. Cosegregation of these polymorphisms with SCA2 patients was established within each family. Together with the results of haplotype analyses, we considered that at least two founders were present in our area and that these (CCG)1-2 polymorphisms may make analysis of founder effects easier. By sequencing analysis we found that although the number of the long CAG repeat varied in each subclone of expanded alleles, these polymorphisms did not change their configuration. This finding suggests that CCG or CCGCCG sequences are stable when surrounded by the long CAG repeat and a single CAG. Moreover, the presence of these polymorphisms may lead to miscounting the repeat size by conventional estimation using a size marker such as an M13 sequencing ladder. Therefore we should consider these polymorphisms and accurately determine the repeat size by sequencing.