gebhart/patrepeval huggingface dataset:
Single Well Microseismic Monitoring Leveraging Hybrid Cable Combining Both DAS and Traditional Geophones (2021)

Abstract The single monitoring well configuration is a favorable option for microseismic monitoring considering risk and cost. It has commonly been used in various industries for decades. When using a single monitoring well, we rely among other things on the waveforms’ polarization information to accurately locate detected microseismic events. Additionally, using a large array aperture reduces hypocenter's uncertainty. Instead of solely relying on 3C geophones to achieve such objectives, we propose to combine 3C sensors and distributed acoustic sensing (DAS) equipment. It is quite a cost-effective solution, and it enables us to leverage each system's strength while minimizing their respective limitations when considered individually. We present the technical feasibility of such a hybrid microseismic monitoring system using data acquired during a monitoring campaign performed in the Montney formation, Canada. In this dataset, the optic fiber (DAS) is located in the wireline cable used to deploy the 3C geophones; themselves located at the bottom of the DAS wireline cable. Though different acquisition systems are employed for the geophone array and the DAS array, both datasets are GPS time stamped so that data can be processed properly. We scan the DAS data using an STA/LTA event detection, and we integrate with the 3C geophone data. We find the microseismic waveform in both the DAS and the geophone sections and confirm the arrival times are consistent between DAS and geophones. Once datasets are merged, we determine hypocenters using a migration-based event location method for such hybrid array. The uncertainty associated with the event located using the hybrid DAS – geophone array is smaller than for any of the systems looked at independently thanks to the increased array aperture. This case study demonstrates the viability and efficiency of the next generation of a single well acquisition system for microseismic monitoring. Not only does it lower event location uncertainty, but it is also more reliable and cost-effective than the conventional approaches.
Refining the localization of the PKD2 locus on chromosome 4q by linkage analysis in Spanish families with autosomal dominant polycystic kidney disease type 2. (1995)

Autosomal dominant polycystic kidney disease (ADPKD) is a genetically heterogeneous disorder. At least two distinct forms of ADPKD are now well defined. In approximately 86% of affected European families, a gene defect localized to 16p13.3 was responsible for ADPKD, while a second locus has been recently localized to 4q13-q23 as candidate for the disease in the remaining families. We present confirmation of linkage to microsatellite markers on chromosome 4q in eight Spanish families with ADPKD, in which the disease was not linked to 16p13.3. By linkage analysis with marker D4S423, a maximum lod score of 9.03 at a recombination fraction of .00 was obtained. Multipoint linkage analysis, as well as a study of recombinant haplotypes, placed the PKD2 locus between D4S1542 and D4S1563, thereby defining a genetic interval of approximately 1 cM. The refined map will serve as a genetic framework for additional genetic and physical mapping of the region and will improve the accuracy of presymptomatic diagnosis of PKD2.
法国哲学家克洛德·列维-施特劳斯百岁仙逝——其思想曾改变了八类学 (2010)

法国哲学家克洛德·列维一施特劳斯因自然原因于周五（10月30日）在巴黎的家中辞世，享年100岁。他因当年所提出的革命性论断——即所谓的原始社会在智慧上并不与现代社会存在重大差异——而被公认为现代人类学之父。
Pitfalls in the diagnosis of autoantibodies associated with paraneoplastic neurologic disease (1996)

We studied the sera of 15 patients with Sjögren's syndrome using the Western blot technique for the presence of anti-Ro and anti-Hu (type 1 antineuronal nuclear autoantibody [ANNA-1]). All sera reacted with Ro-52 protein. Two of the Sjögren sera reacted with 38-kd bands on Western blots of rat cerebellar homogenate, resembling anti-Hu immunoreactivity. However, when reacted with purified human Purkinje cells or purified recombinant HuD protein, none of the sera immunoreacted with the Hu antigens. We recommend the use of either a recombinant Hu protein or the combination of immunohistochemistry and Western blot of purified human neuronal preparations to identify paraneoplastic antibodies. This approach will prevent the unnecessary workup for suspected lung cancer.
Increased LRG1 Levels in Overweight and Obese Adolescents and Its Association with Obesity Markers, Including Leptin, Chemerin, and High Sensitivity C-Reactive Protein (2022)

Leucine-rich α-2 glycoprotein1 (LRG1) is a member of the leucine-rich repeat (LRR) family that is implicated in multiple diseases, including cancer, aging, and heart failure, as well as diabetes and obesity. LRG1 plays a key role in diet-induced hepatosteatosis and insulin resistance by mediating the crosstalk between adipocytes and hepatocytes. LRG1 also promotes hepatosteatosis by upregulating de novo lipogenesis in the liver and suppressing fatty acid β-oxidation. In this study, we investigated the association of LRG1 with obesity markers, including leptin and other adipokines in adolescents (11−14 years; n = 425). BMI-for-age classification based on WHO growth charts was used to define obesity. Plasma LRG1 was measured by ELISA, while other markers were measured by multiplexing assay. Median (IQR) of LRG1 levels was higher in obese (30 (25, 38) µg/mL) and overweight (30 (24, 39) µg/mL) adolescents, compared to normal-weight participants (27 (22, 35) µg/mL). The highest tertile of LRG1 had an OR [95% CI] of 2.55 [1.44, 4.53] for obesity. LRG1 was positively correlated to plasma levels of high sensitivity c-reactive protein (HsCRP) (ρ = 0.2), leptin (ρ = 0.2), and chemerin (ρ = 0.24) with p < 0.001. Additionally, it was positively associated with plasma level of IL6 (ρ = 0.17) and IL10 (ρ = 0.14) but not TNF-α. In conclusion, LRG1 levels are increased in obese adolescents and are associated with increased levels of adipogenic markers. These results suggest the usefulness of LRG1 as an early biomarker for obesity and its related pathologies in adolescents.
Local transport properties of coated conductors by laser-scan imaging methods (2016)

To observe the superconducting current and structural properties of high critical temperature (<TEX>$T_c$</TEX>) superconductors (HTS), we suggest the following imaging methods: Room temperature imaging (RTI) through thermal heating, low-temperature bolometric microscopy (LTBM) and Raman scattering imaging. RTI and LTBM images visualize thermal-electric voltages as different thermal gradients at room temperature (RT) and superconducting current dissipation at near-<TEX>$T_c$</TEX>, respectively. Using RTI, we can obtain structural information about the surface uniformity and positions of impurities. LTBM images show the flux flow in two dimensions as a function of the local critical currents. Raman imaging is transformed from Raman survey spectra in particular areas, and the Raman vibration modes can be combined. Raman imaging can quantify the vibration modes of the areas. Therefore, we demonstrate the spatial transport properties of superconducting materials by combining the results. In addition, this enables visualization of the effect of current flow on the distribution of impurities in a uniform superconducting crystalline material. These imaging methods facilitate direct examination of the local properties of superconducting materials and wires.
Multi-domain system models integration for faults detection in induction motor drives (2014)

The power electronic converters, electric machines, and mechanical loads are key parts of the electric drives systems, and these components are usually modeled and analyzed using specific simulation tools. The overall performances of the electric drives are influenced by system's interconnected components. One solution, to investigate the interaction between different parts of these multi-domain systems, is to integrate them into only one simulation environment. This paper presents the development of two integrated models of a three-phase induction motor (IM) drive: one, based on d-q machine model using MATLAB/Simulink-Simscape, the second being based on finite element analysis (FEA) motor model using ANSYS Simplorer/Maxwell software. The goal is to analyze the system models capabilities to simulate the faults detection caused by failures of different drive's components. The motor current signature analysis is used, in this paper, for monitoring the operation of the IM fed through a pulse-width-modulated (PWM) power inverter. Finally, two case studies are presented, one illustrating the effects of a faulty device of the PWM inverter, and the second case demonstrating the influence of the IM's stator fault. Another objective of this study is to provide users a convenient way of instruction in the area of faults detection and power quality of alternating current (ac) machines and drives.
Reducing metric sensitivity in randomized trajectory design (2002)

This paper addresses the trajectory design for generic problems that involve: (1) complicated global constraints that include nonconvex obstacles, (2) nonlinear equations of motion that involve substantial drift due to momentum, and (3) a high-dimensional state space. Our approach to these challenging problems is to develop randomized planning algorithms based on rapidly-exploring random trees (RRTs). RRTs use metric-induced heuristics to conduct a greedy exploration of the state space; however, performance substantially degrades when the chosen metric does not adequately reflect the true cost-to-go. In this paper, we present a version of the RRT that refines its exploration strategy in the presence of a poor metric. Experiments on problems in vehicle dynamics and spacecraft navigation indicate substantial performance improvement over existing techniques.
Adipose tissue as a possible therapeutic target for polyphenols: A case for Cyclopia extracts as anti-obesity nutraceuticals (2019)

Obesity is a significant contributor to increased morbidity and premature mortality due to increasing the risk of many chronic metabolic diseases such as type 2 diabetes, cardiovascular disease and certain types of cancer. Lifestyle modifications such as energy restriction and increased physical activity are highly effective first-line treatment strategies used in the management of obesity. However, adherence to these behavioral changes is poor, with an increased reliance on synthetic drugs, which unfortunately are plagued by adverse effects. The identification of new and safer anti-obesity agents is thus of significant interest. In recent years, plants and their phenolic constituents have attracted increased attention due to their health-promoting properties. Amongst these, Cyclopia, an endemic South African plant commonly consumed as a herbal tea (honeybush), has been shown to possess modulating properties against oxidative stress, hyperglycemia, and obesity. Likewise, several studies have reported that some of the major phenolic compounds present in Cyclopia spp. exhibit anti-obesity effects, particularly by targeting adipose tissue. These phenolic compounds belong to the xanthone, flavonoid and benzophenone classes. The aim of this review is to assess the potential of Cyclopia extracts as an anti-obesity nutraceutical as underpinned by in vitro and in vivo studies and the underlying cellular mechanisms and biological pathways regulated by their phenolic compounds.
Estimated sdLDL-C for predicting high-risk coronary plaque features in psoriasis: a prospective observational study (2023)

gov . Unique identifiers: NCT01778569.
Detection with phaseless measurements (2016)

We consider the problem of hypothesis testing for detection of a signal in Gaussian noise. We assume that the vector of measurements is unobserved, and that our observations consist of phaseless inner products with a set of known measurement vectors. This is typical of the phase retrieval problem, where the goal is to recover the vector of measurements. We provide a simple estimator for the test statistic that does not necessitate a phaseless recovery method to reconstruct the measurements. Our analysis shows that for random measurement vectors, we can reconstruct the test statistic for any signal from a sufficient number of observations, quadratic in the signal length, using a simple least-squares approach. The primary advantage of this method its simplicity and computational efficiency, which comes at the expense of requiring many more measurements. We show that for Fourier measurements vectors, our approach works only when the signal is also a Fourier vector.
Impact of the inclusion of hydrotalcite on the morphological and electrical characteristics of an epoxy-based CNT nanocomposite (2012)

The experimental results concerning the correlation between morphological and electrical characteristics of a MWCNT/epoxy based composites are presented. The impact of a nanoclay filler is investigated on the DC conductivity of a matrix loaded with different concentrations of MWCNT in order to evaluate the improvements on the dispersion of CNT inside the epoxy matrix. The dispersion is deemed to be very influencing on the electrical conductivity of the nanocomposite. A detailed morphological and structural characterization allows to interpret the electrical behaviour of the nanocomposites.
Wide Viewing Angle Liquid Crystal Displays (2006)

In this dissertation, novel phase compensation technologies are applied to the designs of wide viewing angle and high transmittance liquid crystal displays. First, a design of wide viewing angle liquid crystal displays utilizing crossed linear polarizers is proposed. The designed multi-domain vertical-alignment liquid crystal display predicts superb contrast ratio over wide viewing angles. Next, to increase the bright state transmittance while maintain the high contrast. Finally, to reduce the cost and improve the applicability of the broadband and wide-view circular polarizer, the device configuration of the broadband and wide-view circular polarizer is significantly simplified by the application of biaxial compensation films. The produced states of polarization remain close to the ideal circular polarization over a wide range of incident angles within the visual spectrum. With this circular polarizer, the presented wide-view liquid crystal display predicts high contrast ratio as well as high and uniform transmittance over wide viewing angles within the visual spectrum. ratio, wide viewing angle circular polarizers are developed. The produced states of polarization are very close to the ideal circular state of polarization over a wide range of incident angles within the visual spectrum. This guarantees not only high contrast ratio but also high and uniform transmittance.
The Absorption Spectra of Tetracyclones (1953)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Absorption Spectra of TetracyclonesStephen B. Coan, Donald E. Trucker, and Ernest I. BeckerCite this: J. Am. Chem. Soc. 1953, 75, 4, 900–903Publication Date (Print):February 1, 1953Publication History Published online1 May 2002Published inissue 1 February 1953https://pubs.acs.org/doi/10.1021/ja01100a037https://doi.org/10.1021/ja01100a037research-articleACS PublicationsRequest reuse permissionsArticle Views320Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Evidence of altered matrix composition in iliac crest biopsies from patients with idiopathic juvenile osteoporosis (2015)

IJO bone, similar to PMO bone, had elevated collagen maturity relative to its age-matched controls. This emphasizes the importance of the collagen matrix for bone health. IJO bone differed from PMO bone as IJO bone contains more recently formed mineral than age-matched controls but has a more mature matrix, whereas in PMO bone both mineral and matrix have older characteristics.
The Therapeutic Potential of Hepatocyte Growth Factor for Myocardial Infarction and Heart Failure (2004)

Hepatocyte growth factor (HGF) is a cytokine whose multipotent actions are mediated by c-Met receptor. This review focuses on effects of HGF on myocardial infarction (MI) and heart failure. Circulating concentrations of HGF and myocardial concentrations of HGF and c-Met mRNA and protein are substantially increased following acute MI. HGF has been shown to be cardioprotective towards acute cardiac ischemia-reperfusion injury. Gene transfection of HGF into rat hearts attenuates acute ischemia injury. Administration of HGF protein reduces infarct size and increases cardiac performance in a rat model of acute ischemia/reperfusion. In contrast, acute blockade of endogenous HGF increases infarct size and mortality. These acute effects of HGF appear to be related to angiogenic and anti-apoptotic mechanisms. Recent studies demonstrate that post-MI treatment with HGF gene or protein attenuates chronic cardiac remodeling and dysfunction. In rats, HGF gene transfer following large MI results in preserved cardiac function and geometry in association with angiogenesis and reduced apoptosis, and treatment with recombinant HGF also significantly improves cardiac performance measured 8 weeks after MI. In mice, post-MI HGF gene therapy improves cardiac remodeling and dysfunction through hypertrophy of cardiomyocytes, infarct wall thickening, preservation of vessels, and antifibrosis. In addition, gene transfer of HGF improves cardiac remodeling, angiogenesis and regional myocardial function in the chronic ischemic myocardium of dogs. Together, these preclinical data highlight the significant acute and chronic cardioprotective effects of HGF following ischemic heart failure. Clinical trials are needed to investigate the therapeutic potential of HGF for postinfarction heart failure in humans.
Gastric precancerous process in a high risk population: cohort follow-up. (1990)

In an attempt to characterize the natural history of the gastric precancerous process, 1422 residents of a high risk area of Nariño, Columbia, have been followed from 3-16 years (average 5.1) with repeated gastric biopsies, for a total of 7290 person-years. The original cohort consisted of 1788 individuals yielding a successful completion rate of 79.5%. Comparison of initial and subsequent biopsies revealed a very complex dynamic flow of both progressive and regressive events, suggesting sporadic environmental forces of modulation. One-time measurement of gastric juice, pH, and nitrite failed to predict future events in the gastric mucosa. The net loss of individuals whose gastric mucosa initially showed normal histology or superficial gastritis was 3.3%/year, representing a net gain of 1.7% for chronic atrophic gastritis, 0.9% for intestinal metaplasia, and 0.7% for dysplasia. The incidence rate of gastric cancer in this population was 0.16/100 person-years. The net rates of progression were higher and those of regression lower in older compared to younger individuals. The general pattern detected is that of a slow forward movement in the previously described hierarchical organization of precursor lesions. The presence of progressive as well as regressive changes and the slow pace of change offer special opportunities to inhibit progression through intervention strategies targeting previously identified etiological factors. The difficulties and opportunities offered by the long term follow-up studies as well as the congruency of the findings with current etiological hypotheses are discussed.
Supplementary tables from IFNγ PET Imaging as a Predictive Tool for Monitoring Response to Tumor Immunotherapy (2023)

&lt;p&gt;Primer sequences and biodistribution data for the anti-IFN-gamma PET tracer are shown.&lt;/p&gt;
The Effectiveness of Different Learner Dictionaries : An Investigation into the Use of Dictionaries for Reading Comprehension by Intermediate Learners of German, Ursula Wingate : book review (2006)

Unlike the long tradition of EFL dictionaries, German learners' dictionaries are quite recent and were first marketed in the 1990s. Ursula Wingate's book is quite unique, since studies in German learners' dictionaries are very few, as is empirical research conducted in dictionary use.
Studies of Differently Induced Peroxidation Phenomena in Lecithins (1996)

Egg and soya phospholipids, in the form of liposomes, were analyzed to evaluate lipid peroxidation by means of UV and fluorescence measurements. Oxidation processes were induced by different methods: sonication, UV radiation, and incubation with ferrous ions/ascorbic acid. Aging effect and pH influence were also investigated. The obtained results showed that tested vegetable phospholipids, because of their higher content in polyunsaturated fatty acids, were in all cases much more rapidly oxidized with respect to the animal ones; furthermore, an inverse relationship between the starting hydroperoxide level and the oxidation rate of phospholipids was observed. In the case of soya lecithin a sharp increase in the peroxidation rate was appreciated in slightly alkaline environmental conditions. No effects on peroxidation were ever observed when UV radiations with λ = 254 nm were used. Keywords: Lipid peroxidation; egg lecithins; soya lecithins
Accuracy of store-and-forward diagnosis in leprosy (2008)

Telemedicine might increase the speed of diagnosis for leprosy and reduce the development of disabilities. We compared the accuracy of diagnosis made by telemedicine with that made by in-person examination. The cases were patients with suspected leprosy at eight public health clinics in outlying areas of the city of São Paulo. The case history and clinical examination data, and at least two clinical images for each patient, were stored in a web-based system developed for teledermatology. After the examination in the public clinic, patients then attended a teaching hospital for an in-person examination. The benchmark was the clinical examination of two dermatologists at the university hospital. From August 2005 to April 2006, 142 suspected cases of leprosy were forwarded to the website by the doctors at the clinics. Of these, 36 cases were excluded. There was overall agreement in the diagnosis of leprosy in 74% of the 106 remaining cases. The sensitivity was 78% and the specificity was 31%. Although the specificity was low, the study suggests that telemedicine may be a useful low-cost method for obtaining second opinions in programmes to control leprosy.