gebhart/patrepeval huggingface dataset:
JROTC, but with Scientists (2012)

The Junior Reserve Officer Training Corps (JROTC) attempts to recruit military officers from High Schools by having them interact with military officers. Ed Morrison from Barrow County Schools, and Warren Matthews from Georgia Tech will talk to us about using a Race to the Top Grant to use scientists and engineers to recruit students into the Science Technology Engineering and Mathematics (STEM) fields. The main difference as that this program uses more interactive video conferences with scientists and fewer pushups. Georgia Tech Biomedial Engineering student Katelyn Roberts also explains how this Direct to Discovery program in Barrow county motivated her current educational path.
Pumps and pumping operations (1992)

Flow dynamics and pumping principles pumps and pumping services industrial pumps and their applications oscillating displacement pumps systems analysis for pumping equipment mechanical seals. Appendix: summary of pump engineering data.
Formation Damage vs. Solid Particles Deposition Profile during Laboratory Simulated PWRI (2003)

Abstract The importance of produced water re-injection (PWRI) is unquestionable. It is in many cases the cheapest and most environmentally friendly solution for wastewater disposal. It is also a feasible method for EOR as a water flooding mechanism. PWRI, however, suffers from a major limitation, which is the current inability in accurately predicting the lifespan and performance of its injection wells. This is due to the multitude of parameters that affect it. Current models 1-2 exist that incorporate the thermal effects 3 of PWRI leading to fracture growth. However, the leak-off pattern of this injection differs from that of clean water (seawater) injection due to the damage caused by the produced water onto the formation and especially the fracture faces. Thus, static filtration experiments with refined post-mortem analysis have been conducted to obtain quantitative deposition profiles along the core. This allows for the testing and verification of existing models 4-7. The post-mortem analysis introduced in this paper will be used for future dynamic filtration experiments as well as experiments specifically devised to simulate the fracture tip area. A unified model that will accurately reproduce the permeability decline and deposition profile for all three sets of experiments will flow, thus advancing the predictability of injectivity decline associated with PWRI. A detailed description of the post-mortem analysis will be presented. Testing of existing heuristic models Wennberg5 and Bedrikovedski7 will be published in the near future.
Chemical conversion of gibberellin A4143 to gibbrellin A4. (1976)

Gibberellin A13 was converted into gibberellin A4 through oxidative decarboxylation of C-10 carboxyl with lead tetraacetate followed by C-4→C-10 lactone formation.
Technical and economic optimization of natural gas transmission network operation to balance node delivery flow rate and operation cost (2021)

Natural gas transmission network is the major facility connecting the upstream gas sources and downstream consumers. In this paper, a multi-objective optimization model is built to find the optimum operation scheme of the natural gas transmission network. This model aims to balance two conflicting optimization objective named maximum a specified node delivery flow rate and minimum compressor station power consumption cost. The decision variables involve continuous and discrete variables, including node delivery flow rate, number of running compressors and their rotational speed. Besides, a series of equality and inequality constraints for nodes, pipelines and compressor stations are introduced to control the optimization results. Then, the developed optimization model is applied to a practical large tree-topology gas transmission network, which is 2,229 km in length with 7 compressor stations, 2 gas injection nodes and 20 gas delivery nodes. The ɛ-constraint method and GAMS/DICOPT solver are adopted to solve the bi-objective optimization model. The optimization result obtained is a set of Pareto optimal solutions. To verify the validity of the proposed method, the optimization results are compared with the actual operation scheme. Through the comparison of different Pareto optimal solutions, the variation law of objective functions and decision variables between different optimal solutions are clarified. Finally, sensitivity analyses are also performed to determine the influence of operating parameter changes on the optimization results.
Digesting a Path Forward: The Utility of Collagenase Tumor Treatment for Improved Drug Delivery (2018)

Collagen and hyaluronan are the most abundant components of the extracellular matrix (ECM) and their overexpression in tumors is linked to increased tumor growth and metastasis. These ECM components contribute to a protective tumor microenvironment by supporting a high interstitial fluid pressure and creating a tortuous setting for the convection and diffusion of chemotherapeutic small molecules, antibodies, and nanoparticles in the tumor interstitial space. This review focuses on the research efforts to deplete extracellular collagen with collagenases to normalize the tumor microenvironment. Although collagen synthesis inhibitors are in clinical development, the use of collagenases is contentious and clinically untested in cancer patients. Pretreatment of murine tumors with collagenases increased drug uptake and diffusion 2-10-fold. This modest improvement resulted in decreased tumor growth, but the benefits of collagenase treatment are confounded by risks of toxicity from collagen breakdown in healthy tissues. In this review, we evaluate the published in vitro and in vivo benefits and limitations of collagenase treatment to improve drug delivery.
Advanced Oxidation Processes for Treating Groundwater Contaminated With TCE and PCE: Pilot‐Scale Evaluations (1988)

This article presents the results of a pilot‐scale evaluation of an advanced oxidation process that utilizes hydrogen peroxide and ozone. Treatment efficiency was determined as a function of the hydrogen peroxide‐to‐ozone dosage ratio, ozone dosage, and contact time. The ozone mass transfer characteristics of the process were also investigated. Comparison with other treatment technologies indicates that advanced oxidation can be a cost‐effective treatment process for controlling the common chlorinated organics found in groundwater.
What Will Your Future Child Look Like? Modeling and Synthesis of Hereditary Patterns of Facial Dynamics (2017)

Analysis of kinship from facial images or videos is an important problem. Prior machine learning and computer vision studies approach kinship analysis as a verification or recognition task. In this paper, first time in the literature, we propose a kinship synthesis framework, which generates smile videos of (probable) children from the smile videos of parents. While the appearance of a child's smile is learned using a convolutional encoder-decoder network, another neural network models the dynamics of the corresponding smile. The smile video of the estimated child is synthesized by the combined use of appearance and dynamics models. In order to validate our results, we perform kinship verification experiments using videos of real parents and estimated children generated by our framework. The results show that generated videos of children achieve higher correct verification rates than those of real children. Our results also indicate that the use of generated videos together with the real ones in the training of kinship verification models, increases the accuracy, suggesting that such videos can be used as a synthetic dataset.
Arc Fault Diagnostics in Aircraft Electrical Systems (2002)

&lt;div class="htmlview paragraph"&gt;This paper will address the parallel fault locating theories and subsequent fault locating system developments at General Dynamics. Since 1999, General Dynamics has been investigating technologies and methods for reducing the threat of electrical fires on board aircraft. Early in 2001, efforts were directed to employ technology findings towards tools that could be used by aircraft operators and manufacturers in maintenance or installation validation scenarios.&lt;/div&gt;
R ‐Curve Behavior and Flaw Insensitivity of Ce‐TZP/Al 2 O 3 Composite (1993)

A ceria‐partially‐stabilized zirconia‐aiumina (Ce‐TZP/Al 2 O 3 ) composite optimized for transformation toughening was used to demonstrate its flaw insensitivity due to R ‐curve behavior. Four‐point bend specimens fabricated with a controlled distribution of spherical pores showed nearly the same characteristic strength and strength variability (Weibull modulus) as specimens fabricated without the artificial pores. In situ observations confirmed stable growth of cracks initiated at pores and the crack lengths at fracture instability were much greater than the pore sizes, thus resulting in fracture strengths insensitive to the pores. The small variability in the fracture strength was found to be associated with variability in the R ‐curve and the instability crack lengths. An analysis based on the fracture instability criterion for rising crack growth resistance accounted for the strength variability due to variability in the R ‐curve. Comparable four‐point bend experiments were also conducted on a sintered yttria‐partially‐stabilized zirconia (2Y‐TZP) ceramic. This ceramic showed significant degradation of strength due to the presence of the pores. This flaw sensitivity is attributed to its steep rising R ‐curve over short crack lengths.
Transport Properties of SrTiO3 Thermoelectric Oxides Under Controlled pO2. (2013)

Abstract not provided.
Integrated Virtual Voltage Vectors and Duty Cycle Control to Minimize the Current Ripples in Finite Control Set Model Predictive Control for Permanent Magnet Synchronous Motor Drives (2019)

Finite Control Set Model Predictive Control (FCSMPC) is widely acknowledged as a simple and effective control scheme for permanent magnet synchronous motor (PMSM) drives. It delivers the merit of quick dynamic response however faces problems such as large current ripples and unsatisfactory steady state performance. This paper proposes a FCSMPC method which minimizes the current ripples by integrating the concept of duty cycle and virtual voltage vectors. In the proposed method, six symmetrically positioned virtual voltage vectors are introduced in addition to the six original active voltage vectors to expand the finite control set, among which one optimal vector is selected and applied in each sampling interval according to the enumeration-based principle of cost function minimization. Then, the duration of the optimal vector is decided by an efficiently calculated duty ratio. Compared to the conventional FCSMPC, the proposed method causes no additional computation burden but exhibits much lower current ripples. The proposed method is experimentally compared with two typical FCSMPC methods for an interior permanent magnet synchronous machine and it is proved that the proposed method delivers better steady-state performance while maintaining quick dynamic response.
Uncoded Space-Time Labeling Diversity (2016)

In this letter, we apply labeling diversity to a space-time block coded system, which does not require channel coding or bit interleaving. The proposed system is investigated for both Rayleigh frequency-flat fast and quasi-static fading channels. The theoretical average bit error probability of the system is formulated using the union bound approach. A possible optimization criterion for the design of the mappers for both M-ary quadrature amplitude modulated and M-ary phase shift keying modulated systems is suggested; however, due to a large solution space, a simple method is investigated.
Large-area MOVPE growth for HEMT LSI (2002)

Reports on metalorganic vapor phase epitaxy (MOVPE) for high electron mobility transistor (HEMT) LSI. The low-pressure barrel reactor can grow twelve 3-inch wafers at a time. It is shown that the grown layers meet the demands for LSI application. The authors fabricated HEMT devices with gates 0.6 mu m long using photolithography, with excellent characteristics. They applied the MOVPE technique to HEMT 64 Kb SRAM and obtained a typical address access time of 1.2 ns at a power dissipation of 5.9 W.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
<title>Uncooled microearth sensor for microsatellite attitude control</title> (2000)

MEMS technology now makes possible to produce active microdevices combining detection, signal processing, and data storage with accuracy and compactness. In view of their characteristics, it can be expected that such microsensors will be used extensively in space applications dedicated to micro and nano satellites. For this purpose, a specific investigation dealing with the complete development of a micro-earth sensor used for attitude control of Low Earth Orbit satellites is under realization and test.
E4BP4/NFIL3 modulates the epigenetically repressed RAS effector RASSF8 function through histone methyltransferases (2018)

RAS proteins are major human oncogenes, and most of the studies are focused on enzymatic RAS effectors. Recently, nonenzymatic RAS effectors (RASSF, RAS association domain family) have garnered special attention because of their tumor-suppressive properties in contrast to the oncogenic potential of the classical enzymatic RAS effectors. Whereas most members of RASSF family are deregulated by promoter hypermethylation, RASSF8 promoter remains unmethylated in many cancers but the mechanism(s) of its down-regulation remains unknown. Here, we unveil E4BP4 as a critical transcriptional modulator repressing RASSF8 expression through histone methyltransferases, G9a and SUV39H1. In line with these observations, we noticed a negative correlation of RASSF8 and E4BP4 expression in primary breast tumor samples. In addition, our data provide evidence that E4BP4 attenuates RASSF8-mediated anti-proliferation and apoptosis, shedding mechanistic insights into RASSF8 down-regulation in breast cancers. Collectively, our study provides a better understanding on the epigenetic regulation of RASSF8 function and implicates the development of better treatment strategies.
Does bilateral inferior turbinate reduction affect long‐term quality‐of‐life outcomes in patients undergoing endoscopic sinus surgery? (2019)

Patients undergoing ESS achieve similar long-term improvement in both disease-specific and general QOL regardless of the performance of concurrent BITR.
Factors Associated with Impaired Hematopoietic Recovery after CD19-Targeted CAR-T Cell Therapy (2020)

IntroductionDespite promising results in patients with relapsed/refractory B cell malignancies, CD19 CAR-T cell therapy can be associated with significant toxicities. Specifically, impaired hematopoietic recovery can be observed in a subset of patients.ObjectivesWe aimed to describe hematopoietic recovery following CD19 CAR-T cell therapy, and to identify factors independently associated with this complication using multivariable modeling.MethodsWe retrospectively analyzed 125 adult patients with R/R acute lymphoblastic leukemia (ALL), non-Hodgkin lymphoma (NHL), and chronic lymphocytic leukemia (CLL), treated with CD19 CAR-T cells on a phase 1/2 clinical trial (characteristics summarized in Table 1). Criteria for neutropenia, thrombocytopenia, and recovery were defined as per the CIBMTR reporting guidelines. For competing risk analysis, an event was defined as ANC or platelet (Plt) recovery, with death, new cytotoxic therapy, relapse with marrow involvement in the absence of ANC or platelet recovery considered as competing events. Patient, disease, and CAR-T cell therapy-related variables were included in multivariable analyses.ResultsANC and Plt recovery after CD19 CAR-T cell therapy were observed in 91% (ALL, 86%; CLL, 92%; NHL, 95%) and 86% (ALL, 86%; CLL, 86%; NHL, 84%) of patients, respectively. Median time to ANC recovery was 9 days and the probability of ANC recovery at day 28, 60, and 90 was 80% (95%CI, 73-87), 86% (95%CI, 80-92) and 89% (95%CI, 83-94), respectively. The probability of platelet recovery on the day of CAR-T cell infusion was 55% (95%CI, 46-64); rising to 74% (95%CI, 67-82), 83% (95%CI, 76-90), and 84% (95%CI, 77-90) on days 28, 60, and 90, respectively. A competing event was always observed in patients without ANC or Plt recovery.In multivariable analysis (Table 2), higher pre-lymphodepletion (LD) Plt count and higher peak CD8+ CAR-T cells in blood were associated with faster ANC recovery. A diagnosis of ALL was associated with slower ANC recovery. (CLL vs ALL, HR=1.60, p=0.02; NHL vs ALL, HR=2.07, p=0.007). Higher CRS grade was also associated with slower Plt recovery (HR=0.67 per grade increase, p<0.001). Higher pre-LD Plt count (HR=1.08 per 25 × 109/L increase, p=0.001) and higher peak CD8+ CAR-T cell in blood (HR=1.41 per log10 cells/µL increase, p<0.001) were associated with faster Plt recovery. Figure 1 shows cumulative incidence of ANC and Plt recovery by CRS grade.ConclusionWe observed impaired ANC and Plt recovery in a significant fraction of patients undergoing CD19 CAR-T cell therapy. Moreover, we identified factors independently associated with impaired hematopoietic recovery: disease type, prelymphodepletion Plt count, in vivo CAR-T cell expansion, and CRS grade. In addition to providing a benchmark for future CAR-T cell research, our findings suggest CRS prevention might improve hematopoietic recovery after CD19 CAR-T cell therapy.
Ecological inference using data from accelerometers needs careful protocols (2021)

Abstract Accelerometers in animal-attached tags have proven to be powerful tools in behavioural ecology, being used to determine behaviour and provide proxies for movement-based energy expenditure. Researchers are collecting and archiving data across systems, seasons and device types. However, in order to use data repositories to draw ecological inference, we need to establish the error introduced according to sensor type and position on the study animal and establish protocols for error assessment and minimization. Using laboratory trials, we examine the absolute accuracy of tri-axial accelerometers and determine how inaccuracies impact measurements of dynamic body acceleration (DBA), as the main acceleration-based proxy for energy expenditure. We then examine how tag type and placement affect the acceleration signal in birds using (i) pigeons Columba livia flying in a wind tunnel, with tags mounted simultaneously in two positions, (ii) back- and tail-mounted tags deployed on wild kittiwakes Rissa tridactyla . Finally, we (iii) present a case study where two generations of tag were deployed using different attachment procedures on red-tailed tropicbirds Phaethon rubricauda foraging in different seasons. Bench tests showed that individual acceleration axes required a two-level correction (representing up to 4.3% of the total value) to eliminate measurement error. This resulted in DBA differences of up to 5% between calibrated and uncalibrated tags for humans walking at different speeds. Device position was associated with greater variation in DBA, with upper- and lower back-mounted tags in pigeons varying by 9%, and tail- and back-mounted tags varying by 13% in kittiwakes. Finally, DBA varied by 25% in tropicbirds between seasons, which may be attributable to tag attachment procedures. Accelerometer accuracy, tag placement, and attachment details critically affect the signal amplitude and thereby the ability of the system to detect biologically meaningful phenomena. We propose a simple method to calibrate accelerometers that should be used prior to deployments and archived with resulting data, suggest a way that researchers can assess accuracy in previously collected data, and caution that variable tag placement and attachment can increase sensor noise and even generate trends that have no biological meaning.
Microfaunal response to fertilization of an arctic tundra stream (1995)

SUMMARY 1. As part of a whole‐system study, the response of the heterotrophic microfaunal community colonizing artificial substrata (polyfoam units) to fertilization of an arctic tundra stream was followed for 6 weeks during the summer. 2. Dominant heterotrophic microfauna observed included amoebae (approximately 40% of colonizing biomass), rotifers (36% of biomass) and ciliates (25% of biomass). 3. Biomass of heterotrophic microfauna on artificial substrata was not significantly different in a control reach and an experimental reach fertilized with phosphorus (loading rate ten times ambient), but in a reach fertilized with both phosphorus and nitrogen (loading rates ten times ambient) biomass was double that of the control and phosphorus‐fertilized reaches. The lack of response in the phosphorus reach was probably due to greater insect grazing as a result of previous phosphorus fertilization of this reach. 4. Abundance of microfauna on epilithic surfaces in the river was higher on rocks from pools than on rocks from riffle areas, but abundance on the artificial substrata was higher than on the natural rocks. 5. The results suggest that microfauna of arctic tundra streams are regulated by grazers and that their importance in transfers among trophic levels is greater in pools than in riffles.
A PWM Buck Converter With Load-Adaptive Power Transistor Scaling Scheme Using Analog-Digital Hybrid Control for High Energy Efficiency in Implantable Biomedical Systems (2016)

We report a pulse width modulation (PWM) buck converter that is able to achieve a power conversion efficiency (PCE) of > 80% in light loads 100 μA) for implantable biomedical systems. In order to achieve a high PCE for the given light loads, the buck converter adaptively reconfigures the size of power PMOS and NMOS transistors and their gate drivers in accordance with load currents, while operating at a fixed frequency of 1 MHz. The buck converter employs the analog-digital hybrid control scheme for coarse/fine adjustment of power transistors. The coarse digital control generates an approximate duty cycle necessary for driving a given load and selects an appropriate width of power transistors to minimize redundant power dissipation. The fine analog control provides the final tuning of the duty cycle to compensate for the error from the coarse digital control. The mode switching between the analog and digital controls is accomplished by a mode arbiter which estimates the average of duty cycles for the given load condition from limit cycle oscillations (LCO) induced by coarse adjustment. The fabricated buck converter achieved a peak efficiency of 86.3% at 1.4 mA and > 80% efficiency for a wide range of load conditions from 45 μA to 4.1 mA, while generating 1 V output from 2.5-3.3 V supply. The converter occupies 0.375 mm(2) in 0.18 μm CMOS processes and requires two external components: 1.2 μF capacitor and 6.8 μH inductor.
News and Short Contributions (1977)

Amadou-Mahtar M'bow, Shirley Gorenstein, R. Ross Holloway, Robert Carmack, Stephen L. Dyson, William L. Kelso, Ned Nabers, Ronald Spores, T. Cuyler Young, Jr., News and Short Contributions, Journal of Field Archaeology, Vol. 4, No. 2 (Summer, 1977), pp. 259-265