gebhart/patrepeval huggingface dataset:
Adolescent understanding of DOHaD concepts: a school-based intervention to support knowledge translation and behaviour change (2012)

A life-course approach to reduction of risk of non-communicable diseases (NCD) suggests that early-life interventions may be more effective than lifestyle modifications in middle age. Knowledge translation to develop understanding of the Developmental Origins of Health and Disease (DOHaD) within the community offers the potential to encourage informed diet and lifestyle choices supporting reduction of NCD risk in current and future generations. Many women do not make sustained dietary change before or during pregnancy, therefore appropriate nutritional behaviours need to be established prior to adulthood. This makes adolescence an appropriate stage for interventions to establish suitable dietary and lifestyle behaviours. Therefore, we engaged adolescents in a school-based educational intervention, and assessed the value of this in development of understanding of DOHaD concepts to support behaviour change that could lead to NCD risk reduction in the next generation. Modules of course work were written for 11-14 year olds and trialled in nine schools. Matched pre- and post-intervention questionnaire responses from 238 students and 99 parents, and post-intervention interviews evaluated the intervention. Understanding of a link between maternal diet during pregnancy and the health of the foetus in adulthood increased from 46% to 76% following intervention. Post-intervention evidence suggests the programme facilitated discussion of diet, lifestyle and DOHaD concepts in most families. The intervention was effective in improving understanding of DOHaD concepts and in some cases led to appropriate behaviour change. However, the sustainability of these changes remains to be determined through on-going evaluation of attitudes and behaviour within this cohort.
Versatile Solid-Phase Synthesis of Peptide-Derived 2-Oxazolines. Application in the Synthesis of Ligands for Asymmetric Catalysis (2005)

A mild and high-yielding procedure for the solid-phase synthesis of 2-oxazolines from amino acids is described. The two-step protocol is based on the iodination of serine containing peptides, followed by in situ nucleophilic attack of the carbonyl oxygen from the next amino acid. Phosphinylation of the terminal amino group cleanly furnishes a resin-bound phosphine-oxazoline ligand, which upon palladium complexation was applied as catalyst in asymmetric allylic substitution. [reaction: see text]
Deep Subwavelength Light Confinement in Disordered Bismuth Nanorods as a Linearly Thermal‐Tunable Metamaterial (2020)

Materials with a tunable optical response that can be controllably tailored using external stimuli excitation have undergone considerable research effort for the development of active optical devices, such as thermo‐optical modulators. Although bismuth (Bi) nanodots, embedded into glass matrices, have been proven to have a thermo‐optical response, the recyclability of the structure in solid–liquid phase transitions is a major challenge. Herein, a facile and lithography‐free fabrication method is proposed to realize densely packed stand‐alone Bi nanorods (NRs), with deep subwavelength gaps and a resonance at the midinfrared range (λ ≅ 4.462 μm). Owing to these ultrasmall gaps that support lossy Mie‐like resonances, strong field confinement is achieved, and the resonance wavelength exhibits great sensitivity to temperature, as the thermal sensitivity reaches as high as 1.0316 nm °C −1 . This operation is conducted in the moderate temperature interval of 25–85 °C, which is far from the melting point of Bi. Overall, our simple, robust, and high‐performance device is highly promising for realizing optical switches, thermo‐optic modulators, and infrared camouflage.
Acoustic emission of steel-fiber concrete under four-point bending (2009)

This work deals with the AE behavior of concrete under four-point bending. Different contents of steel fibers were included to investigate their influence on the load-bearing capacity and on the fracture mechanisms. The AE waveform characteristics revealed that, although tension was the dominant mechanism of fracture for the plain material, the increase in the fiber content resulted in extension of the shear failure due to improvement of the weak tensile properties of concrete. Appropriate AE indices employed for early warning prior to macroscopic failure can lead to more suitable design of the reinforcement, in order to withstand the specific stresses.
Editorial. Use of fixation/fusion to treat lumbar spinal stenosis (2019)

T he authors present a paper that challenges many long-established principles in the treatment of lumbar spinal stenosis (LSS). 1 They treated 70 consecutive patients with LSS over a 4-year period with posterior lumbar fixation and fusion-without performing neural decompressions-as the sole treatment modality. This concept is unique and new to the treatment of lumbar spine disorders.
Glycaemic index of cereal products explained by their content of rapidly and slowly available glucose (2003)

Elucidating the role of carbohydrate quality in human nutrition requires a greater understanding of how the physico-chemical characteristics of foods relate to their physiological properties. It was hypothesised that rapidly available glucose (RAG) and slowly available glucose (SAG), in vitro measures describing the rate of glucose release from foods, are the main determinants of glycaemic index (GI) and insulinaemic index (II) for cereal products. Twenty-three products (five breakfast cereals, six bakery products and crackers, and twelve biscuits) had their GI and II values determined, and were characterised by their fat, protein, starch and sugar contents, with the carbohydrate fraction further divided into total fructose, RAG, SAG and resistant starch. Relationships between these characteristics and GI and II values were investigated by regression analysis. The cereal products had a range of GI (28-93) and II (61-115) values, which were positively correlated (r(2)) 0.22, P<0.001). The biscuit group, which had the highest SAG content (8.6 (SD 3.7) g per portion) due to the presence of ungelatinised starch, was found to have the lowest GI value (51 (SD 14)). There was no significant association between GI and either starch or sugar, while RAG was positively (r(2)) 0.54, P<0.001) and SAG was negatively (r(2)) 0.63, P<0.001) correlated with GI. Fat was correlated with GI (r(2)) 0.52, P<0.001), and combined SAG and fat accounted for 73.1% of the variance in GI, with SAG as the dominant variable. RAG and protein together contributed equally in accounting for 45.0 % of the variance in II. In conclusion, the GI and II values of the cereal products investigated can be explained by the RAG and SAG contents. A high SAG content identifies low-GI foods that are rich in slowly released carbohydrates for which health benefits have been proposed.
New Insight into Studies of the Cycling Performance of Li-Graphite Electrodes (2005)

Based on a combination of cyclic voltammetry, chronoamperometry, and electrochemical impedance spectroscopy techniques, a new method of self-discharge characterization of lithiated graphite electrodes as a function of cycle number has been elaborated. Different domains were identified in the plot of the self-discharge current, vs. cycle number. During the beginning of cycling, the electrode's impedance and , both decrease as cycling proceeds. This is due to reorganization and reformation of the surface films on the electrode surface. After several tens of consecutive cycles, start to increase. In parallel, the impedance of the deintercalated graphite electrode increases as well. Both and the electrode's impedance reach steady value upon prolonged cycling. This relates to the semiconducting properties of the surface films formed on the electrode surface which change upon cycling toward an increasingly better electronic conductivity of the surface films (their passivity decreases). This, in turn, creates favorable conditions for electroadsorption of Li ions on the surface films of the long-term cycled electrode reflected as an increase in . A porous electrode model was adopted in order to qualitatively describe the evolution of the impedance spectra of the fully lithiated graphite electrodes with cycle number, at room temperature.
COMPOSITION AND DIGESTIBILITY BY PIGS OF HULL FRACTIONS FROM RAPESEED CULTIVARS WITH YELLOW OR BROWN SEED COATS (1982)

Hull fractions from yellow seed (Brassica campestris 'R-500') and brown seed (Brassica napus 'Tower') cultivars of rape were fed to pigs at levels of 0, 15 and 30% of the diet in a digestibility trial. Whole seed, 'meats' (embryo) and hull fractions were analyzed for moisture, protein, ether extract, crude fiber, neutral and acid detergent fiber, lignin, ash, calcium, phosphorus, sinapine, glucosinolates and gross energy. Brown hulls contained more fiber and lignin. The embryo content of the yellow hulls fraction was greater than that of the brown hulls fraction. Increasing dietary levels of hulls depressed digestibility of dry matter, energy, crude fiber and ether extract. Brown hulls had the greatest effect. The effect on ether extract digestibility may have been due to lower digestibility of unextracted oil in embryo fractions adhering to hulls. The digestibility coefficients of Tower and R-500 added oils were 87 and 75%, respectively, and the same oils residing in the meats were 36 and 44% digestible. The energy components of hulls per se were more digestible in R-500 than in Tower. Protein of Tower hulls was indigestible, but R-500 hull protein was about 20% digestible. Key words: Rapeseed hulls, yellow brown, composition, digestibility, pigs
Growth And Characterization Of Nd,Cr:Gsgg Laser Crystals (1987)

The growth and characterization of Nd,Cr:GSGG crystals for laser applications is described.
Extracellular matrix profiles determine risk and prognosis of the squamous cell carcinoma subtype of non-small cell lung carcinoma (2022)

Collectively, this analysis defines matrix-driven features of poor prognosis to inform precision medicine prevention and treatment strategies towards improving SqCC patient outcome.
Probabilistic Mapping of August 2018 Flood of Kerala, India, Using Space-Borne Synthetic Aperture Radar (2020)

Synthetic aperture radar (SAR) imaging provides an all-weather sensing technique that is suitable for near-real-time mapping of disasters such as floods. In this article, we use SAR data acquired by Sentinel-1A/B satellites to investigate a flood event that affected the Indian state of Kerala in August 2018. We apply a Bayesian approach to generate probabilistic flood maps, which contain for each pixel its probability to be flooded rather than binary flood information. We find that the extent of the flooded area begins to increase throughout Kerala after August 8, with the highest values on August 9 and August 21. We observe no apparent correlation between the spatial distributions of the flooded areas and the rainfall amounts at the district level of the study area. Instead, larger flooded areas are in the districts of Alappuzha and Kottayam, located in the downstream floodplain of the Idduki dam, which released a significant volume of water on August 16. The lack of apparent correlation is likely due to two reasons: first, there is often some delay between the rainfall event and the flooding, especially for rather large catchments where flood waves need some time to reach floodplains from higher elevations. Second, rainfall is more abundant at overhead catchments (hills and mountains), whereas flood occurs further downstream in the floodplains. Further comparison of our SAR-based flood maps with optical data and flood maps produced by moderate resolution imaging spectroradiometer highlights the advantages of our data and approach for rapid response purposes and future flood forecasting.
Evidence for integrins other than β2 on polymorphonuclear neutrophils: expression of α6β1 heterodimer (1993)

The expression of non-beta 2 integrins on polymorphonuclear neutrophils (PMNs) was analyzed by immunoprecipitation and flow cytometry using platelet-free PMN preparations and anti-Fc gamma R blocking mAbs. No beta 3 integrin was detected with six anti-beta 3 mAbs. Conversely, integrin beta 1 chain was present on PMNs, although at low level, and could be distinguished from platelet beta 1 by SDS-PAGE. The MW differences disappeared after N-glycanase treatment. PMNs express only 2500 molecules of beta 1 per cell and this expression is not modulated by agonists such as phorbol myristate acetate, formylmethionyl-leucyl-phenylalanine, granulocyte-macrophage colony-stimulating factor, or tumor necrosis factor alpha, which enhance CD11b expression, or by interferon-gamma or transforming growth factor beta. PMNs were found to express alpha 6 associated with beta 1, and no reactivity was observed with various anti-alpha 1, anti-alpha 2, anti-alpha 3, anti-alpha 4, anti-alpha 5 or anti-alpha V mAbs. In conclusion, although other leukocytes express various beta 1 integrins, which mediate cell interactions with ECM proteins, PMNs appear to express only the laminin receptor alpha 6 beta 1. PMN interactions with non-laminin ECM ligands thus seem to be mediated either exclusively by beta 2 integrins or by nonintegrin molecules.
Brain Inflammation, Neuropsychiatric Disorders, and Immunoendocrine Effects of Luteolin (2014)

Theoharides, Theoharis C. BA, MS, MPhil, MD, PhD; Conti, Pio DSc; Economu, Marina MD, DSc Author Information
The evolution of concepts of vestibular peripheral information processing: toward the dynamic, adaptive, parallel processing macular model (2003)

In a letter to Robert Hooke, written on 5 February, 1675, Isaac Newton wrote "If I have seen further than certain other men it is by standing upon the shoulders of giants." In his context, Newton was referring to the work of Galileo and Kepler, who preceded him. However, every field has its own giants, those men and women who went before us and, often with few tools at their disposal, uncovered the facts that enabled later researchers to advance knowledge in a particular area. This review traces the history of the evolution of views from early giants in the field of vestibular research to modern concepts of vestibular organ organization and function. Emphasis will be placed on the mammalian maculae as peripheral processors of linear accelerations acting on the head. This review shows that early, correct findings were sometimes unfortunately disregarded, impeding later investigations into the structure and function of the vestibular organs. The central themes are that the macular organs are highly complex, dynamic, adaptive, distributed parallel processors of information, and that historical references can help us to understand our own place in advancing knowledge about their complicated structure and functions.
Proceedings of the IFIP TC2/TC13 WG2.7/WG13.4 Seventh Working Conference on Engineering for Human-Computer Interaction (1998)

From the Publisher:
This book comprises the proceedings of the Seventh Working Conference on Engineering for Human-Computer interaction sponsored by the International Federation for Information Processing (IFIP), which was held in Heraklion, Greece in September 1998. It contains research articles authored by researchers from all over the world, who set out to explore and evaluate new techniques for designing and building user interfaces or groupware systems. It also contains the reports of workshops held during the conference on the most recent research issues raised by user-interface engineering.
<title>Direct laser writing of conductive pathways into diamond-like carbon films</title> (1990)

Continuous wave laser microprocessing of diarrnd-1ike carbon films deposited on silicon is reported The conductive lines of 3-15 pm width with resistivity Lj . jo—2 ccm were formed into dielectric amcrphous film via its graphitization as evidenced by Rarnan spectroscopy. When the temperature within a laser spot rises up to 6000C the carbon oxidation starts, resulting in the film etching and the narrow channels formation The reflectivity in visible of the anneal ed DLC fi ims I s studied regarding them as a candidate for optical recording ridia.
The Addition of Ketenes to α,β-Unsaturated Ethers (1960)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Addition of Ketenes to α,β-Unsaturated EthersCharles D. Hurd and R. D. Kimbrough Jr.Cite this: J. Am. Chem. Soc. 1960, 82, 6, 1373–1376Publication Date (Print):March 1, 1960Publication History Published online1 May 2002Published inissue 1 March 1960https://pubs.acs.org/doi/10.1021/ja01491a022https://doi.org/10.1021/ja01491a022research-articleACS PublicationsRequest reuse permissionsArticle Views184Altmetric-Citations21LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A multichannel collision free MAC protocol for wireless ad hoc networks (2009)

Thinking of multiple frequency channels in wireless ad hoc networks can significantly improve the throughput if advanced MAC protocols are employed. The efficiency of multichannel protocols mainly depends on the channel assignment strategy, which has to assure both fairness and low signaling overhead. Taking into account these needs, the present work proposes a new multichannel MAC protocol, based on the balanced incomplete block design (BIBD) theory. In details, the protocol we propose is time slotted, collision free, and assures a fair distribution of both available frequency channels and time slots, thanks to the BIBD resolvability feature. Exploiting the peculiarities of BIBD, procedures for handling network topology modifications with a low overhead have been also developed. Finally, analytical results have shown very high channel utilization, efficiency, and global energy saving.
Visualization of Web access logs using Data Jewelry Box (2002)

This paper presents a tool for visualizing Web access logs, which has two views. The left view represents Web sitemaps by a set of webpage icons. It places the icons onto display spaces by data jewelry box algorithm. The right view represents Web access statistics by a bar chart. It aggregates the accesses according to user-specified attributes, such as time, client, and status. When a user clicks a bar in the right view, the left view highlights icons that have corresponding accesses. When a user clicks an icon in the left view, the right view shows the access statistics of the clicked webpage. These combinations of the two views help users to find problems of websites, and discover trends of accesses.
Recent advances in pericyte biology--implications for health and disease. (1991)

This review highlights the contributions of recent pericyte research towards our understanding of normal and pathological functioning of microvessels. Pericytes are implicated in a variety of microvascular alterations, including wound healing, diabetes, inflammation, hypertension and neoplasia. They are capable of changing into other mesodermally derived cell types, including smooth muscle cells, osteoblasts and chondrocytes. The contractile properties of pericytes are being systematically examined in vitro; in addition to their tendency to contract spontaneously, pericytes can contract further in response to mediators of inflammation. In vivo studies indicate pericytes are concentrated near endothelial cell junctions along venules where they likely participate in inflammatory events. As agents are identified which modify pericyte responses to disease states, better therapeutic approaches will become possible.
Effect of ethanol on pro-apoptotic mechanisms in polarized hepatic cells (2007)

Chronic ethanol consumption is associated with serious and potentially fatal alcohol-related liver injuries such as hepatomegaly, alcoholic hepatitis and cirrhosis. Moreover, it has been documented that the clinical progression of alcohol-induced liver damage may be associated with an increase in hepatocellular death that involves apoptotic mechanisms. Although much information has been learned about the clinical manifestations associated with alcohol-related diseases, the search continues for a better understanding of the molecular and/or cellular mechanisms by which ethanol exerts its deleterious effects such as the induction of pro-apoptotic mechanisms and related cell damaging events. As part of the effort to enhance our understanding of those particular cellular pathways and mechanisms associated with ethanol toxicity, researchers over the years have utilized a variety of model systems. Recently, work has come forth demonstrating the utility of a hybrid cell line (WIF-B) as a cell culture model system for the study of alcohol-associated alterations in hepatocellular mechanisms. Success with such emerging model systems could aid in the development of potential therapeutic treatments for the prevention of alcohol-induced apoptotic cell death that may ultimately serve as a significant target in delaying the onset and/or progression of clinical symptoms of alcohol-mediated liver disease. This review article summarizes the current understanding of ethanol-mediated modifications in cell survival and thus the promotion of pro-apoptotic events with emphasis on analyses made in various experimental model systems, particularly the more recently characterized WIF-B cell system.
Supplementary Information from Preclinical Therapeutic Synergy of MEK1/2 and CDK4/6 Inhibition in Neuroblastoma (2023)

&lt;p&gt;This document contains Supplementary information, including materials and methods as well as Figure Legends for the Supplementary Figures.&lt;/p&gt;
ChemInform Abstract: Cellulose Crystallites (2002)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.