gebhart/patrepeval huggingface dataset:
Adaptive Impedance Control of Human–Robot Cooperation Using Reinforcement Learning (2017)

This paper presents human-robot cooperation with adaptive behavior of the robot, which helps the human operator to perform the cooperative task and optimizes its performance. A novel adaptive impedance control is proposed for the robotic manipulator, whose end-effector's motions are constrained by human arm motion limits. In order to minimized motion tracking errors and acquire an optimal impedance mode of human arms, the linear quadratic regulation (LQR) is formulated; then, integral reinforcement learning (IRL) has been proposed to solve the given LQR with little information of the human arm model. Considering human-robot interaction force during the robot performing manipulation, a novel barrier-Lyapunov-function-based adaptive impedance control incorporating adaptive parameter learning is developed for physical limits, transient perturbations, and time-varying dynamics. Experimental results validate that the proposed controller is effective in assisting the operator to perform the human-robot cooperative task.
Near infrared laser annealing of CdTe and in-situ measurement of the evolution of structural and optical properties (2016)

The high performance of polycrystalline CdTe thin film solar cells is enabled by annealing in the presence of Cl. This process is typically carried out for tens of minutes resulting in reduction of defect states within the bandgap among other beneficial effects. In this work, we investigate laser annealing as a means of rapidly annealing CdTe using a continuous wave sub-bandgap 1064 nm laser. The partial transmission of the beam allows us to monitor the annealing process in-situ and in real time. We find that optoelectronic and structural changes occur through two distinct kinetic processes resulting in the removal of deep defects and twinned regions, respectively. A multilayer optical model including surface roughness is used to interpret both the in-situ transmission as well as ex-situ reflectivity measurements. These experiments demonstrate beneficial material changes resulting from sub-bandgap laser-driven CdCl2 treatment of CdTe in minutes, which is an important step towards accelerating the processing of the CdTe absorber layer.
Longitudinal Assessment of a Transgenic Animal Model of Tauopathy by FDG-PET Imaging (2014)

Abnormal levels and hyperphosphorylation of tau protein have been proposed as the underlying cause of a group of neurodegenerative disorders collectively known as 'tauopathies'. The detrimental consequence is the loss of affinity between this protein and the microtubules, increased production of fibrillary aggregates, and the accumulation of insoluble intracellular neurofibrillary tangles. A similar phenotype can be observed in various preclinical models, which have been generated to study the role of tau protein in neurodegenerative disorders. In this study, we have analyzed the brain metabolic activity in an animal model of tauopathy (tauVLW transgenic mice), which has been previously reported to mimic some of the phenotypic features of these disorders. By using a non-invasive technique, positron emission tomography (PET), a longitudinal non-clinical follow up study was carried out during most of the lifespan of these transgenic mice, from the youth to the senescence stages. The results obtained point out to an aging-dependent decrease in 18F-fluoro-deoxyglucose (FDG) uptake in the cerebral areas analyzed, which was already significant at the adult age, i.e., 11 months, and became much more prominent in the oldest animals (19 months old). This observation correlates well with the histopathological observation of neurodegeneration in brain areas where there is overexpression of tau protein.
Stimulating capacity of blast cells from patients with chronic myelocytic leukaemia, in blastic crisis in 'one-way' mixed lymphoycte reaction: lack of evidence for T lymphoblastic conversion. (1978)

It has long been suggested that the blastic transformation in some patients with Ph1-positive chronic myelocytic leukaemia (CML) may be lymphoid in nature. It has recently been postulated that some patients with CML may undergo a T lymphoblastic crisis because the leukaemic blasts from these patients have high terminal deoxynucleotidyl transferase (TdT) activity and that some patients may undergo a non-T/non-B lymphoblastic crisis since leukaemic blasts from a majority of morphologically lymphoid type CML-BC cases react with antiserum specific for non-T/non-B acute lymphoblastic leukaemia (ALL). The present study shows that leukaemic blasts from each of six patients with Ph1-positive chronic myelocytic leukaemia-blastic crisis (CML-BC) exerted a strong stimulation on allogeneic lymphocytes in 'one-way' mixed lymphocyte reaction. There was no apparent difference in stimulating capacity between morphologically myeloid type (four cases) and lymphoid type (two cases). The stimulating capacity of leukaemic blasts from patients with CML-BC was quite similar to that of blasts from all patients with acute myeloblastic leukaemia (AML) and from some patients with non-T/non-B type ALL. Leukaemic blasts from a patient with T-cell type ALL and cultured leukaemic T lymphoblastoid cells (2 lines) consistently failed to stimulate while cultured leukaemic null-cells (4 lines) consistently exerted a strong stimulation in 'one-way' mixed lymphocyte reaction. These observations suggest that leukaemic cells from patients with CML-BC, morphologically lymphoblastic type, are not T lymphoblasts although the possibility that these cells are non-T/non-B lymphoblasts cannot be ruled out entirely.
A novel current control strategy for PWM inverters using the sliding mode techniques (2002)

Classical PWM techniques are replaced by current source sliding mode control (SMC) deciding the IGBT's status in real time by using a FPGA. Utility synchronization and inverter management is guaranteed by Park vector transformation. Three novel sliding strategies for current controlled PWM inverters are described, and several simulations show the performance of the inverter control.
Colorado Potato Beetle (Coleoptera: Chrysomelidae): Residual Mortality and Artificial Weathering of Formulated Bacillus thuringiensis subsp. tenebrionis (1997)

Potato foliage was treated with commercially formulated Bacillus thuringiensis subsp. tenebrionis Berliner and was exposed to simulated rain at different times after spray application. The treated foliage was then fed to 2nd-instar Colorado potato beetle. Leptinotarsa decemlineata (Say), and larvae were held at different constant temperatures. Simulated rain applied within 30 min of the insecticide application to foliage and subsequent larval exposure to low temperature (19ºC) resulted in the lowest larval mortality. This was also confirmed under field conditions. The chronic effects of B. thuringiensis subsp. tenebrionis on larvae that survived initial exposure were studied. For these survivors, there was high mortality during the pupal stage and there was a delay in development to the adult stage. This mortality generally goes undetected in the field, and therefore the overall mortality caused by B. thuringiensis subsp. tenebrionis may be underestimated.
High Power Photoconductive Switch of 4H-SiC with Damage-Free Electrodes by Using n<sup>+</sup>-GaN Subcontact Layer (2006)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
[P4–125]: THE MOLECULAR CHAPERONE BRICHOS INHIBITS Aβ AGGREGATION AND OTHER NEUROPATHOLOGICAL PHENOTYPES IN A MOUSE MODEL OF Aβ AMYLOIDOSIS (2017)

The aggregation of the amyloid β-peptide (Aβ) is hypothesized to initiate the pathogenesis of Alzheimer's disease (AD). In order to prevent or treat AD, strategies to inhibit Aβ accumulation and toxicity in the brain are extensively explored. BRICHOS, a molecular chaperone protein, is possibly one of the physiological protection mechanisms against amyloid formation. Three recombinant adeno-associated viruses (rAAVs) encoding Bri-BRICHOS domain, proSP-C-BRICHOS domain or GFP, were injected to cerebral ventricles of newborn mice using somatic brain transgenesis method. 4 μl of each rAAV8 particles (1*1012genome particles/ml) were injected into newborn APP/PS1 mice (male, n=8 for each group). Eight months after rAAV8 injection, cognitive function and AD-related neuropathological phenotypes were analyzed in cortex. We demonstrate that molecular chaperone BRICHOS domains significantly decreased Aβ levels, inhibited amyloid accumulation, greatly reduced astroglial activation, and prevented cognitive decline in APP/PS1 mice. Together, our results show that the molecular chaperone BRICHOS domain promotes protein homeostasis and decreases the severity of Aβ aggregation and its associated pathology in the brain. These data suggest that the BRICHOS domain can be further investigated as a promising preventive and therapeutic strategy against AD.
Biosorption of Pb(II) ontoCocos NuciferaShell andMoringa OleiferaSeeds (2014)

The biosorption properties of Cocos nucifera shell and Moringa oleifera seeds for Pb(II) were investigated under batch mode. The optimum pH values obtained for the removal of Pb(II) by the Cocos nucifera shell and the Moringa oleifera seeds were 5 and 2, respectively. The equilibrium biosorption capacities obtained were 2.3 mg g−1 (Moringa oleifera seeds) and 1.6 mg g−1 (Cocos nucifera shell). The Freundlich isotherm model described the removal of Pb(II) by the biosorbents better than the Langmuir model. The Cocos nucifera shell sorbed 83.34% of the Pb(II) ions in 30 min, while 94.03% was sorbed by the Moringa oleifera seeds in the same time. The results indicated a fast kinetics for Pb(II) sorption by the biosorbents investigated. The biosorption of Pb(II) onto Cocos nucifera shell and Moringa oleifera seeds followed the pseudo second-order kinetics with R2 values of 0.9997 and 0.9999, respectively. The second-order rate constant (k2) obtained were 0.205 g mg−1 min−1 (Cocos nucifera shell) and 0.067 g mg−1 min−1 (Moringa oleifera seeds). The results indicate that intraparticle diffusion controls the rate of biosorption in this study. This study shows that Cocos nucifera shell and Moringa oleifera seeds can be important low-cost biosorbents for Pb(II) ions.
Role of Neutrophils and Nitric Oxide in Lung Alveolar Injury from Smoke Inhalation (1994)

We examined potential mechanisms responsible for the parenchymal lung injury seen in an animal model of smoke inhalation with concurrent inflammation. Rats injected with sterile glycogen and exposed to smoke generated by the nonflaming pyrolysis of combined Douglas fir wood and polyvinylchloride showed a 74% increase in 125I-albumin lung permeability and a fivefold increase in lung myeloperoxidase (MPO) compared with control rats. There was also a significant increase in plasma indices of oxidative injury in these animals. Compared with control animals, plasma concentrations of thiobarbituric acid reactive substances (TBARS) were elevated by 62%, the concentrations of reduced sulfhydryl groups declined by 37%, and the levels of dinitrophenylhydrazine-reactive proteins (DNPH-RP) were doubled. In addition, the plasma concentrations of nitrate (NO3-) in rats exposed to glycogen plus smoke were increased three times that of control animals. Injection of the nitric oxide synthase inhibitor, NG-nitro-L-arginine methyl ester (L-NAME), immediately after smoke exposure or induction of neutropenia using either nitrogen mustard or antineutrophil antiserum, abolished the increase in concentrations of circulating NO3-, and prevented changes in plasma concentrations of TBARS, DNPH-RP, lung MPO activity, and tissue permeability index. These data suggest that neutrophil activation and the production of nitric oxide-derived oxidants contribute to the lung and plasma indices of oxidative injury in this smoke inhalation model.
Electroplated Thick Manganese Oxide Films with Ultrahigh Capacitance (2013)

Ultrahigh specific capacitance and excellent cyclic retention of MnO2 can be achieved in a novel sandwich electrode loaded with a large amount of MnO2 by utilizing the open porosity of dealloyed nanoporous metals. The highly conductive nanoporous metals, as both support of active materials and current collector of supercapactior, dramatically enhance the electronic/ionic conductivity and charge transfer at three phase interfaces.
Synthesis of 9-fluorenylmethoxycarbonyl-protected amino aldehydes (1998)

9-Fluorenylmethoxycarbonyl-protected amino aldehydes could be efficiently prepared in good yields by using two methods: (i) NaBH4 reduction of Fmoc-protected mixed anhydrides, followed by the Swern oxidation of the alcohols; and (ii) LiAlH4 reduction of Fmoc-protected amino acid Weinreb amides. Both methods afforded comparable overall synthetic yields (70–80%).
History of Bacillus Calmette-Guerin and Bladder Cancer: An Immunotherapy Success Story (2007)

For the last 3 decades bacillus Calmette-Guerin therapy has remained the most effective local therapy for superficial bladder cancer, an outstanding example of successful translational medicine in urology.
Benefits of GaN transistors and embedding in PCB laminates (2019)

International audience
Impact of interfacial structure on the charge dynamics in nanocomposite dielectrics (2019)

We demonstrate that the chemistry at the interface between nanoparticle and polymer matrix influence charge dynamics in polymer nanocomposite. Applying density functional theory, we investigate the influence of crystal surface termination, silicon treatment, and water and carboxyl defect on the electronic properties of interfaces in MgO-polyethylene nanocomposite. The band offsets between the nanofiller and base matrix materials show a strong dependence on the chemical composition at the interface. Based on the calculated electronic structure, we propose a band alignment model for charge dynamics in nanocomposite dielectrics. The model not only provides a mechanism of reduction of space charge and conductivity but also predicts an increase in thermal stress and susceptibility to the chemical additives. It is suggested that the suppression mechanisms of space charge and conductivity in nanocomposites can be inherently unstable and promote material aging. The results of the study show a need for long-term performance tests of nanocomposite dielectrics.
In Vitro Testing of Pharmaceutical Aerosols and Predicting Lung Deposition from In Vitro Measurements (2001)

The major advantage of topical administration of a drug is the possibility to achieve high local concentrations and to avoid high systemic concentrations. In clinical practice, the decision of a physician to initiate a treatment with inhaled β2-agonists or glucocorticosteroids in patients with asthma or chronic obstructive pulmonary disease (COPD) is easy, as their efficacy is beyond any discussion. Adverse reactions to aerosolized drugs are rare (1) and may be circumvented by choosing an alternative formulation or an alternative drug. To deposit in the airways, the drug must be aerosolized, for which an inhalation system is necessary. Pressurized metered dose inhalers (pMDIs), dry-powder inhalers (DPIs), and nebulizers are the currently used delivery systems. Health care providers involved in aerosol therapy should be critically informed about these systems in order to make appropriate comparisons and intelligent choices for their patients. Indeed, each formulation is a unique combination of a drug and a device, and it is that combination, rather than the drug itself, that causes a portion of the emitted dose drug to be deposited in the airways to elicit the clinical effect.
Autonomous predictive driving for blind intersections (2017)

This paper presents a model for safe driving at blind intersections and its integration to a local planner based on a Frenet frame. The model predicts potential moving obstacles from blind intersections to proactively slow down to avoid potential collisions. The derivation of the model is described and its parameters are detailed. The local planner computes smooth trajectories with smooth velocity profiles so that the vehicle can follow the paths without jerk and sudden accelerations resulting in safe and comfortable navigation. Experimental results in simulation and in the real field with an autonomous car, show that the proposed predictive driving framework can reproduce human expert driver's trajectories and velocities when facing blind intersections.
Antibacterial and Antifungal Activities of Complexes of Ruthenium (II) (2011)

Twenty ruthenium (II) complexes (1-5) were evaluated for their in vitro antibacterial and antifungal activity against Enterococcus faecalis (ATCC 29212), Staphylococcus aureus (ATCC 29213), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853), Candida albicans and Candida tropicalis. Compounds 1d, 1e, 1h, 1i and 1j showed more pronounced antimicrobial activity against Gram-positive bacteria and fungi as compared to the nitrogen donor ruthenium complexes; hydrophobic substituents were significantly more effective. None of the compounds 1-5 exhibited antimicrobial activity against the Gram-negative strains Escherichia coli (ATCC 25922) and Pseudomonas aeruginosa (ATCC 27853) with the concentrations ranging between 12.5 and 800 micrograms/ml.
Heat Flux From Process Burners (2001)

Abstract This paper shows the effects of firing rate, excess air, and fuel composition on the heat flux profile from process burners as measured in large pilot-scale test furnaces. Firing rate and excess air had a significant effect on the heat flux profiles while the fuel gas blends studied here had a negligible impact.
Influence of machine symmetry on reduction of cogging torque in permanent-magnet brushless motors (2000)

We study two methods to reduce cogging torque, both based on the analysis of the rotational symmetry in a brushless permanent-magnet motor. The first one seeks to lower the symmetry in the flux of a conventional motor with asymmetrical magnet distribution. The second one uses auxiliary slots to increase the frequency of the cogging. Analytical calculations have been made to predict the harmonic spectra of the models. Numerical calculations by the finite-element method were carried out. The results support the analytical conclusions. The frequency of the torque pulsation was increased, as predicted. We obtain a peak-to-peak cogging torque reduction of about 85% for each of the two methods. Dynamical calculations show no changes in the mean torque produced. The asymmetrical motor could introduce some ripple due to the EMF shifting.
A Unifying View of Sparse Approximate Gaussian Process Regression (2005)

We provide a new unifying view, including all existing proper probabilistic sparse approximations for Gaussian process regression. Our approach relies on expressing the effective prior which the methods are using. This allows new insights to be gained, and highlights the relationship between existing methods. It also allows for a clear theoretically justified ranking of the closeness of the known approximations to the corresponding full GPs. Finally we point directly to designs of new better sparse approximations, combining the best of the existing strategies, within attractive computational constraints.
Development of excitatory amino acid induced cytotoxicity in cultured neurons (1990)

The neurotoxicity of the excitatory amino acids (EAAs) L-glutamate (L-glu), L-aspartate (L-asp), N-methyl-D-aspartate (NMDA), kainate (KA), quisqualate (QA) and RS-alpha-amino-3-hydroxy-5-methyl-4-isoxazolopropionate (AMPA) was followed as a function of development in primary cultures of cerebral cortex neurons and cerebellar granule cells. These two types of neurons express, respectively, glutamate receptor subtypes with sensitivity to all of these excitatory amino acids or only to glutamate and aspartate. None of the EAAs were toxic in cerebral cortex neurons at 2 days in culture, whereas at culture day 4 the neurons became sensitive to glutamate, at day 5 to KA followed by sensitivity to QA at day 6, and finally to NMDA, L-asp and AMPA at day 7. The rank order of potency of the EAAs was in cerebral cortex neurons cultured for 12 days: L-asp (ED50 = 0.5 microM) = L-glu (ED50 = 1 microM) greater than AMPA (ED50 = 10 microM) greater than NMDA (ED50 = 65 microM) greater than QA = KA (ED50 = 100 microM). Cerebellar granule cells were insensitive to all of the EAAs at 3 and 5 days in culture but at day 8 the cells became sensitive to toxicity induced by L-glu (ED50 = 70 microM) and L-asp (ED50 = 30 microM). In order to determine ED50 values for L-asp and L-glu accurately, media in these experiments also contained 500 microM of the glutamate uptake inhibitor L-aspartate-beta-hydroxamate.(ABSTRACT TRUNCATED AT 250 WORDS)
GIVL: Improving Geographical Inclusivity of Vision-Language Models with Pre-Training Methods (2023)

A key goal for the advancement of AI is to develop technologies that serve the needs not just of one group but of all communities regardless of their geographical region. In fact, a significant proportion of knowledge is locally shared by people from certain regions but may not apply equally in other regions because of cultural differences. If a model is unaware of regional characteristics, it may lead to performance disparity across regions and result in bias against underrepresented groups. We propose GIVL, a Geographically Inclusive Vision-and-Language Pre-trained model. There are two attributes of geo-diverse visual concepts which can help to learn geo-diverse knowledge: 1) concepts under similar categories have unique knowledge and visual characteristics, 2) concepts with similar visual features may fall in completely different categories. Motivated by the attributes, we design new pre-training objectives Image Knowledge Matching (IKM) and Image Edit Checking (IEC) to pre-train GIVL. Compared with similar-size models pre-trained with similar scale of data, GIVL achieves state-of-the-art (SOTA) and more balanced performance on geo-diverse V&amp;L tasks.
Fuzzy clustering using local and global region information for cell image segmentation (2014)

In high-throughput applications, accurate segmentation of biomedical images can be considered as an important step for recognizing cells that have the phenotype of interest. In this paper, while conventional fuzzy clustering is not able to implement the local and global spatial information, a novel spatial fuzzy clustering cell image segmentation algorithm is proposed. The segmentation procedure is divided into two stages: the first stage involves processing the local and global spatial information of the given cell image and a final segmentation stage which is based on the idea of conventional fuzzy clustering. Our idea can be considered as a sequential integration of region based methods and fuzzy clustering for cell image segmentation. Experimental results show that the proposed model yields significantly better performance in comparison with several existing methods.