gebhart/patrepeval huggingface dataset:
Seasonal differences in rhythmicity of salivary cortisol in healthy adults (2019)

The existence of seasonal changes in secretion of stress hormones and inflammatory mediators by humans is not certain. Here, we aimed to determine whether concentrations of cortisol and IL-6 displayed seasonal rhythmicity. The study was performed in Poznań, Poland (52°N, 16°E) in 7 healthy female volunteers (age 22.6 ± 0.8 yr). Samples of whole mixed unstimulated saliva were collected in winter (February) and summer (June) at 2-h intervals over a 24-h period and analyzed for cortisol and IL-6 by immunoassays. During each season, the subjects answered questionnaires related to their sleeping habits, food intake, physical activity, and perceived seasonality. It turned out that salivary concentrations of cortisol followed a daily rhythm both in winter and summer, as determined by a cosine analysis. However, compared with the winter season, a midline-estimating statistic of rhythm in the summer was significantly higher. Moreover, the rhythm acrophase occurred ~4 h later in the summer than in the winter, whereas the amplitudes did not differ. These fluctuations did not correspond to sleeping habits, food and fluid intake, physical exercise, and the self-assessed chronotype. However, the individuals with higher scores on the seasonal affective disorder scale showed a tendency toward lower relative cortisol amplitude in the summer. In contrast to cortisol, salivary IL-6 concentration did not display daily rhythmicity, and its concentrations did not differ significantly between the seasons. In conclusion, in the summer, cortisol level in saliva is elevated, and its circadian pattern of secretion is shifted. The causes for these alterations do not seem to be related to lifestyle and thus remain to be established.
Effect of Oxygen Containing Biofuels on the Emissions with ExhaustGas Catalysts (2009)

&lt;div class="htmlview paragraph"&gt;One of the first alternative fuels have been fossil crude oil based containing a small amount of biomass derived compounds (bioethanol or biodiesel). Biofuels usually contain oxygenated hydrocarbons such as alcohols or esters. The increasing use of alternative fuels will occur at the same time when various after-treatment systems (oxidation catalysts, filters, SCR catalysts) will be commercialized world-widely between 2010 and 2020. The effects of biofuels on emissions and emission catalysts were reviewed widely in this study. The change in raw emissions has effects on the selection, performance and durability of catalytic systems.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;Bioethanol has been used widely with emission catalysts since 1990's in Brazil. The results with three-way catalysts (TWC) were analyzed in those conditions. PtRh catalysts showed the better performance and durability than Pd containing TWCs.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;The effect of noble metal type (Pt, Pd, PtPd), loading and space velocity was studied with aged diesel oxidation catalyst samples under laboratory conditions. Ethanol and acetaldehyde were used to simulate biofuel compounds and derivates formed in engine. The formation of acetaldehyde is higher with ethanol than with diesel fuels. The ethanol reactions on oxidation catalysts was experimentally simulated over European Driving Cycle (EDC) in comparison to diesel exhaust gases. The formation and oxidation of acetaldehyde were detected on Pd-containing oxidation catalysts but Pt-only catalyst showed the lowest acetaldehyde formation ability. The net effect is clearly positive to reduce acetaldehyde emissions with efficient oxidation catalyst.&lt;/div&gt;
The sustainability hub (2010)

Sustainability is becoming an increasingly important driver for which decision makers -- consumers, corporate and government -- rely on principled, accurate and provenanced metrics to make appropriate behavior changes. Our assertion here is that a Sustainability Hub which manages such metrics together with their context and chains of reasoning will be of great benefit to the global community. In this paper we explain the Hub vision and explain its triple value proposition of context, chains of reasoning and community. We propose a data model and describe our existing prototype.
Fast algorithms for generating binary holograms (2014)

We describe three algorithms for generating binary-valued holograms. Our methods are optimised for producing large arrays of tightly focussed optical tweezers for trapping particles. Binary-valued holograms allow us to use a digital mirror device (DMD) as the display element, which is much faster than other alternatives. We describe how our binary amplitude holograms can be used to correct for phase errors caused by optical aberrations. Furthermore, we compare the speed and accuracy of the algorithms for both periodic and arbitrary arrangements of traps, which allows one to choose the ideal scheme depending on the circumstances.
Strategies for the Synthesis of Thermoplastic Polymer Nanocomposite Materials with High Inorganic Filling Fraction (2013)

The governing parameters controlling the miscibility of particle additives within polymeric host media are analyzed for the particular case of silica particle fillers embedded within a poly(methyl methacrylate) (PMMA) matrix. For athermal polymer-graft modification of particles (corresponding to equal chemical composition of graft and matrix polymer), compatibility is found to be a sensitive function of the degree of polymerization of graft and host polymer chains as well as the particle radius. In agreement with theoretical predictions, uniform particle dispersion is observed if the degree of polymerization of grafted chains is comparable to (or exceeds) the corresponding value of the polymer matrix. The resulting restriction to high degree of polymerization limits the accessible inorganic fraction that is attainable in athermal particle/polymer blends. In contrast, favorable interaction between grafted polymer chains and the polymeric host (as realized in the case of poly(styrene-r-acrylonitrile)-grafted particles embedded within PMMA matrix) is shown to facilitate thermodynamically stable and uniform particle dispersion across the entire compositional range even in the limit of large particle size, short grafted chains, and high molecular matrix chains. The synthesis of thermoplastic composite materials with inorganic fraction exceeding 50 vol % combining quantitative optical limiting within the UV frequency range and polymer-like mechanical properties is demonstrated.
The structure of manumycin. III. Absolute configuration and conformational studies. (1987)

Chromic acid oxidation of manumycin (1), an antibiotic produced by Streptomyces parvulus (strain Tü 64), led to the isolation of 2-(2-methyl-4-oxo-2-pentenoylamino)-5,6-epoxy-1,4-benzoquinone (3) and (-)-(R)-2-methylhexanoic acid (4). From the absolute configuration of 4, determined by comparing its optical rotation with published data, follows the absolute configuration at the center of chirality in the diene side chain of manumycin (1) to be (6'R). Based on the direct comparison of the CD spectra of the two chromic acid oxidation products 2 and 3 with those of the antibiotic G7063-2 (5) and (-)-terreic acid (6) the stereochemistry at C-5 and C-6 of 1 was determined as (5R, 6S). From the negative CD-couplet of manumycin (1) its stereochemistry at C-4 was assigned as (4R).
Triglycine sulphate/selenate solid solutions for pyroelectric applications (1976)

The triglycine sulphate-triglycine selenate system is surveyed with particular reference to pyroelectric detector applications. Measurements on single crystals grown with a range of S: Se ratios showed that X-irradiation and alanine doping have analogous effects to those in TGS. The properties of LATGS/Se were found particularly promising in terms of calculated detector performance for a range of conditions. Detectors have been made of these compositions and show low frequency performance corresponding to the calculated limit due to lateral thermal conduction. A detector 15 μm thick had D* = 1.4 × 109 W-1 Hz1/2 cm at 10 Hz and retained a similar performance up to 40°C. The best D* measured was on a 15 μm thick element where D* = 2 × 109 W-1 Hz1/2 cm at 3 Hz.
Structure and kinetics of defects in silicon (1967)

Literature review on kinetics of defect production and migration, and defects in diamond-type lattice, particularly silicon
“I cannot say no when a pregnant woman needs my support to get to the health centre”: involvement of community health workers in Rwanda’s maternal health (2020)

The results of this study highlight the experiences and perceptions of M-CHWs on the provision and access to maternal health services in their communities. The fact that M-CHWs are volunteers operating in limited resources settings with no formal training in maternal health and with considerable workloads translates into challenges regarding the quality and quantity of services they provide in their communities. Such challenges create an impact on M-CHWs service provision, satisfaction and retention. The voices of M-CHWs and the communities they serve are needed to explore areas that are specific to each community context that would contribute to making the M-CHW program sustainable to achieve equitable access to maternal health services.
Addressing Two-Level Systems Variably Coupled to an Oscillating Field (2013)

We propose a simple method to spectrally resolve an array of identical two-level systems coupled to an inhomogeneous oscillating field. The addressing protocol uses a dressing field with a spatially dependent coupling to the atoms. We validate this scheme experimentally by realizing single-spin addressing of a linear chain of trapped ions that are separated by ~3 μm, dressed by a laser field that is resonant with the micromotion sideband of a narrow optical transition.
A Practical Solid‐Phase Synthesis of Glu7‐Phalloidin and Entry into Fluorescent F‐Actin‐Binding Reagents (2007)

Einfache Synthese einer leistungsfähigen Sonde: Eine effiziente Festphasensynthese von Glu7-Phalloidin (das harzgebundene cyclische Peptid ist gezeigt) beruht auf dem I2-vermittelten Entschützen von S-Tritylcystein und der Bildung der Thioetherbrücke zwischen Cys und Trp. Ein fluoreszierendes Konjugat des resultierenden Phalloidin-Analogons färbt F-Actin (filamentöses Actin) in fixierten Säugerepithelzellen spezifisch an (siehe Fluoreszenzbild). Fmoc=9-Fluorenylmethoxycarbonyl.
In vivo characterization of indentation stiffness of articular cartilage in the normal human knee (1999)

Previous laboratory measurements showed topographical variation in the properties of articular cartilage in several animal species and in humans. In this study we characterize for the first time the topographical variation of the stiffness of the human knee articular cartilage in vivo using a novel arthroscopic indentation instrument. The instrument indicates the stiffness in the form of force (Newtons) by which the tissue resists the constant deformation (300 microm) produced by the small (1-mm diameter) cylindrical indenter. Measurements were carried out at eight sites in the knee joint of 20 persons who had intact cartilage in the arthroscopic examination. The stiffest cartilage (5.6 +/- 1.2 N, mean +/- SD) was located in the lateral condyle of the femur, whereas the softest cartilage (2.4 +/- 0.8 N) was in the medial plateau of the tibia. In general, the cartilage stiffness was higher in the femur than in the tibia (p < 0. 01) or in the patella (p < 0.01). In the femur, the condyles were stiffer than the patellar surface (p < 0.01). The stiffness variation was consistent with earlier biphasic indentation analyses of laboratory measurements with the knee joint cartilage of cadavers. This study provides baseline data for characterization of cartilage stiffness in pathological situations or follow-up of the cartilage quality after surgical interventions.
Harnessing the power of Social Bookmarking for improving tag-based Recommendations (2014)

Social bookmarking and tagging has emerged a new era in user collaboration. Collaborative Tagging allows users to annotate content of their liking, which via the appropriate algorithms can render useful for the provision of product recommendations. It is the case today for tag-based algorithms to work complementary to rating-based recommendation mechanisms to predict the user liking to various products. In this paper we propose an alternative algorithm for computing personalized recommendations of products, that uses exclusively the tags provided by the users. Our approach is based on the idea of using the semantic similarity of the user-provided tags for clustering them into groups of similar meaning. Afterwards, some measurable characteristics of users' Annotation Competency are combined with other metrics, such as user similarity, for computing predictions. The evaluation on data used from a real-world collaborative tagging system, citeUlike, confirmed that our approach outperforms the baseline Vector Space model, as well as other state of the art algorithms, predicting the user liking more accurately.
Rigidity to carbanion inversion of four-, five, six-membered cyclic organomagnesium compounds (1971)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRigidity to carbanion inversion of four-, five, six-membered cyclic organomagnesium compoundsGideon Fraenkel, Engelbert Pechhold, and David G. AdamsCite this: J. Org. Chem. 1971, 36, 10, 1368–1374Publication Date (Print):May 1, 1971Publication History Published online1 May 2002Published inissue 1 May 1971https://pubs.acs.org/doi/10.1021/jo00809a012https://doi.org/10.1021/jo00809a012research-articleACS PublicationsRequest reuse permissionsArticle Views261Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Suppressing nonperturbative gauge errors in the thermodynamic limit using local pseudogenerators (2021)

With recent progress in quantum simulations of lattice-gauge theories, it is becoming a pressing question how to reliably protect the gauge symmetry that defines such models. In a recent work [J. C. Halimeh \textit{et al.}, arXiv:2108.02203], an experimentally feasible gauge-protection scheme has been proposed that is based on the concept of a \textit{local pseudogenerator}, which is required to act identically to the full gauge-symmetry generator in the target gauge sector, but not necessarily outside of it. The scheme has been analytically and numerically shown to reliably stabilize lattice gauge theories in the presence of perturbative errors on finite-size analog quantum-simulation devices. In this work, through uniform matrix product state calculations, we demonstrate the efficacy of this scheme for nonperturbative errors in analog quantum simulators up to all accessible evolution times in the thermodynamic limit, where it is \textit{a priori} neither established nor expected that this scheme will succeed. Our results indicate the presence of an emergent gauge symmetry in an adjusted gauge theory even in the thermodynamic limit, which is beyond our analytic predictions. Additionally, we show through quantum circuit model calculations that gauge protection with local pseudogenerators also successfully suppresses gauge violations on finite quantum computers that discretize time through Trotterization. Our results firm up the robustness and feasibility of the local pseudogenerator as a viable tool for enforcing gauge invariance in modern quantum simulators and NISQ devices.
Activity of human volunteer sera to candidate Plasmodium falciparum circumsporozoite protein vaccines in the inhibition of sporozoite invasion assay of human hepatoma cells and hepatocytes (1990)

Sera from human volunteers immunized with either synthetic peptide (NANP)3-TT or recombinant protein R32tet32 Plasmodium falciparum CS vaccines were tested in the inhibition of sporozoite invasion (ISI) assays using human hepatoma (HepG2-A16) cells or primary human hepatocytes. Sera or purified immunoglobulin (Ig) from volunteers who were completely protected against P. falciparum sporozoite challenge had higher ISI activity than sera from non-protected volunteers, or the highest titre endemic serum. However, Ig from protected and non-protected volunteers did not block sporozoite invasion of human hepatocytes, suggesting that P. falciparum sporozoites invade hepatocytes by mechanisms which differ from those concerned with invasion of HepG2-A16 cells.
A Machine-Learning-Based Auction for Resource Trading in Fog Computing (2020)

Fog computing is considered to be a key enabling technology for future networks. By broadening the cloud computing services to the network edge, fog computing can support various emerging applications such as IoT, big data, and blockchain with low latency and low bandwidth consumption cost. To achieve the full potential of fog computing, it is essential to design an incentive mechanism for fog computing service providers. Auction is a promising solution for the incentive mechanism design. However, it is challenging to design an optimal auction that maximizes the revenue for the providers while holding important properties: IR and IC. Therefore, this article introduces the design of an optimal auction based on deep learning for the resource allocation in fog computing. The proposed optimal auction is developed specifically to support blockchain applications. In particular, we first discuss resource management issues in fog computing. Second, we review economic and pricing models for resource management in fog computing. Third, we introduce fog computing and blockchain. Fourth, we present how to design the optimal auction by using deep learning for the fog resource allocation in the blockchain network. Simulation results demonstrate that the proposed scheme outperforms the baseline scheme (i.e., the greedy algorithm) in terms of revenue, and IC and IR violations. Thus, the proposed scheme can be used as a useful tool for the optimal resource allocation in general fog networks.
Adaptive motion vector refinement for high performance transcoding (2002)

In transcoding, simple reuse of the motion vectors extracted from the incoming bit-stream may introduce severe quality degradation in many applications. In this paper we first discuss the effect of quantization error on the motion vectors. We show that due to the quantization errors, the incoming motion vectors become non-optimal. To achieve the best quality possible, a new motion estimation should be performed in the transcoder. We proposed an adaptive motion vector refinement scheme with a highly reduced computational complexity in comparison to the full-scale motion estimation. We also discuss the case when some incoming frames are dropped for the frame-rate conversion. We propose a simple and fast motion vector interpolation method. We show that the proposed adaptive refinement scheme provides video quality almost as good as that can be achieved by performing a new full-scale motion estimation but requires much less computation.
An in vitro cell irradiation protocol for testing photopharmaceuticals and the effect of blue, green, and red light on human cancer cell lines (2016)

Traditionally, ultraviolet light (100-400 nm) is considered an exogenous carcinogen while visible light (400-780 nm) is deemed harmless. In this work, a LED irradiation system for in vitro photocytotoxicity testing is described. The LED irradiation system was developed for testing photopharmaceutical drugs, but was used here to determine the basal level response of human cancer cell lines to visible light of different wavelengths, without any photo(chemo)therapeutic. The effects of blue (455 nm, 10.5 mW cm(-2)), green (520 nm, 20.9 mW cm(-2)), and red light (630 nm, 34.4 mW cm(-2)) irradiation was measured for A375 (human malignant melanoma), A431 (human epidermoid carcinoma), A549 (human lung carcinoma), MCF7 (human mammary gland adenocarcinoma), MDA-MB-231 (human mammary gland adenocarcinoma), and U-87 MG (human glioblastoma-grade IV) cell lines. In response to a blue light dose of 19 J cm(-2), three cell lines exhibited a minimal (20%, MDA-MB-231) to moderate (30%, A549 and 60%, A375) reduction in cell viability, compared to dark controls. The other cell lines were not affected. Effective blue light doses that produce a therapeutic response in 50% of the cell population (ED50) compared to dark conditions were found to be 10.9 and 30.5 J cm(-2) for A375 and A549 cells, respectively. No adverse effects were observed in any of the six cell lines irradiated with a 19 J cm(-2) dose of 520 nm (green) or 630 nm (red) light. The results demonstrate that blue light irradiation can have an effect on the viability of certain human cancer cell types and controls should be used in photopharmaceutical testing, which uses high-energy (blue or violet) visible light activation.
Peak Shaving Model for Coordinated Hydro-Wind-Solar System Serving Local and Multiple Receiving Power Grids via HVDC Transmission Lines (2020)

To meet the rapid growth of electricity demand and reduce carbon intensity, China is developing renewable energies rapidly including hydropower, wind and solar power. Due to the geographical mismatch of energy sources and demands in China, many long-distance and large-scale UHVDC and HVDC transmission projects have been built to transmit electric power from the western renewable bases to eastern coastal load centers. Some provincial power sources serve both local demands and deliver power to multiple regional power grids via HVDC transmission lines. As large capacity HVDC power transmission projects have great impacts on receiving-end power grids. Thus, the local exporting power grid should consider both local demands and energy importing area demands. A mixed-integer linear programming day-ahead peak shaving model to minimize the peak-valley difference in residual load after renewable generation of multiple power grids is developed. The model uses chance constraints to compensate for forecast errors of wind and solar power with hydropower, and introduces maximum daily power regulation times and stair-like power curve constraints of HVDC tie lines to avoid frequent HVDC power change and ensure power grid safety. The case studies in Yunnan province, which has large scale hydro, wind and solar power sources and delivers power to multiple regional power grids via HVDC transmission lines, shows the proposed model can shave peaks from multiple power grids effectively, hydropower can compensate for wind and solar forecast error and obtain satisfying results for multiple power grids, and that HVDC constraints can avoid their frequent power change and ensure the power grid safety.
Pain Insensitivity in Schizophrenic Patients (1988)

Some schizophrenic patients have decreased pain perception while others have decreased pain expression. These factors frequently lead to difficulties in the diagnosis of acute intra-abdominal surgical emergencies. Increasingly large numbers of schizophrenic patients are being cared for in the community. It is therefore imperative that surgeons be acutely aware of the diagnostic dilemmas presented by this group of patients so that misdiagnosis is avoided and appropriate surgical therapy is instituted in a timely manner.