gebhart/patrepeval huggingface dataset:
Transactional WaveCache: Towards Speculative and Out-of-Order DataFlow Execution of Memory Operations (2008)

The WaveScalar is the first dataflow architecture that can efficiently provide the sequential memory semantics required by imperative languages. This work presents a speculative memory disambiguation mechanism for this architecture, the transaction WaveCache. Our mechanism maintains the execution order of memory operations within blocks of code, called waves, but adds the ability to speculatively execute, out-of-order, operations from different waves. This mechanism is inspired by progress in supporting transactional memories. Waves are considered as atomic regions and executed as nested transactions. Wave that have finished the execution of all their memory operations are committed, as soon as the previous waves are also committed. If a hazard is detected in a speculative wave, all the following waves (children) are aborted and re-executed. We evaluated the transactional WaveCache on a set of benchmarks from Spec 2000, Mediabench and Mibench (telecomm). Speedups ranging from 1.31 to 2.24 (related to the original WaveScalar) where observed when the benchmark doesn't perform lots of emulated function calls or access memory very often. Low speedups of 1.1 to slowdowns of 0.96 were observed when the opposite happens or when the memory concurrency was high.
Shear-Stabilized Bi-axial Texture and Lamellar Contraction in both Diblock Copolymer and Diblock Copolymer/Homopolymer Blends (1996)

Large-amplitude oscillatory shear was applied to a poly(styrene-b-ethylenepropylene) diblock copolymer and also to binary blends of this copolymer with homopolystyrene. The shearing was applied at a temperature above the glass transition and well below the microphase separation transition for long times: 12 h, strain amplitude γ = 40%, frequency ω = 1 rad/s, T = 150 °C. The dynamic moduli decrease during the shearing and after a partial recovery upon annealing at 150 °C display a permanently altered rheological state. Small-angle X-ray scattering studies indicate that the shearing induces a biaxial texture consisting predominantly of a “parallel” orientation which coexists with a nearly “transverse” orientation of lamellae, inclined at ∼80° to the parallel orientation. The shearing also causes a ∼4% decrease in the lamellae spacing of the parallel orientation relative to the unsheared equilibrium state; lamellae in the nearly transverse orientation retain the equilibrium spacing. This lamellar contraction compares favorably to a recent theoretical treatment by Williams and MacKintosh [Macromolecules 1994, 27, 7677]. Upon annealing, the spacing of the lamellae in the parallel orientation expands to recover the equilibrium spacing, and the biaxial texture disappears via the loss of the nearly transverse orientation. After annealing, subjecting the sample to large-amplitude oscillatory shear a second time re-creates the biaxial texture.
An Upward Priority Channel Preemption Scheme for Vertical Handoff in Cellular/WLAN Interworking (2011)

This paper proposes a novel upward priority channel Preemption Scheme (UPPS) for vertical handoff in a cellular/WLAN interworking networks. In order to improve the upward vertical handoff (UVH) dropping probabilities of voice and data calls while guaranteeing system performance and utilization of the cellular bandwidth, the proposed scheme defines priorities for newly cellular calls and UVH calls and designs newly bandwidth allocation scheme and priority preemption rule to modify the channel Preemption Model for Vertical handoff (PMV) scheme. Simulation results show that the proposed scheme enormously improves performance of the voice UVH call dropping probability and the data UVH call dropping probability at the cost of some increasing newly cellular call blocking probability that may tolerate uncritical while keeping high cellular bandwidth utilization compared with PMV. The proposed scheme has much significance in providing good QoS guarantees in cellular /WLAN interworking networks.
Enzymatic fractionation of fatty acids: Enrichment of γ‐linolenic acid and docosahexaenoic acid by selective esterification catalyzed by lipases (1990)

Immobilized lipase preparations from seedlings of rape ( Brassica napus L.) and Mucor miehei (lipozyme) used as biocatalysts in esterification and hydrolysis reactions discriminate strongly against γ‐linolenic and docosahexaenoic acids/acyl moieties. Utilizing this property, γ‐linolenic acid contained in fatty acids of evening primrose oil has been enriched seven to nine‐fold, from 9.5 to almost 85% by selective esterification of the other fatty acids with butanol. Similarly, docosahexaenoic acid of cod liver oil has been enriched four to five‐fold, from 9.4 to 45% by selective esterification of fatty acids (other than docosahexaenoic acid) with butanol. As long as the reaction is stopped before reaching equilibrium, very little of either γ‐linolenic acid or docosahexaenoic acid are converted to butyl esters, which results in high yields of these acids in the unesterified fatty acid fraction.
Millimeter-wave imaging of humans - basic experiments (2006)

Basic experiments and results concerning MMW imaging of human beings with emphasis on people screening in safety crucial environments are discussed. Common network analysis equipment and several mechanical positioning systems are intended to be used to obtain significant pixel images of the human body and other concealed objects. Especially, lens focused pixel images are presented.
Multiprotocol Interconnect over Frame Relay (1992)

Multiprotocol Interconnect over Frame Relay
Late mortality in two-year survivors of hematopoietic cell transplantation (HCT) performed in children and adolescents: Report from the BMT-Survivor Study (2004)

8507 Background: We assessed overall and cause-specific late mortality [death occurring 2 or more years (yrs) after HCT] in a retrospective cohort of 862 patients (pts), unedrgoing HCT between 1974 and 1998, before the age of 21 yrs, and surviving at least 2 yrs. Methods: Vital status information was obtained from medical records, National Death Index, and Social Security Death Index. Age- and sex-standardized mortality ratios (SMR) were calculated using US population mortality data. Results: Primary diagnoses included ALL (n=212), AML (n=205), SAA (n=113), HD/NHL (n=67), inborn errors of metabolism (IEM: n=81), and other diagnoses (n=184). Types of HCT included related donor (RD: n=496), unrelated donor (URD: n=186), and autologous (A-HCT: n=180). Median age at HCT was 9.3 yrs (0.1–20.9) and length of follow-up 10.1 yrs (2.0–28.4). A total of 182 (21%) late deaths were observed. The cohort was at a 20-fold increased risk of late death when compared with the general population. Leading causes of deaths included recurrence of original cancer (61%) and chronic graft vs. host disease (cGVHD) (12%). Excess mortality rates were also seen due to pulmonary complications (SMR=41.5, 95%CI,18.8–73.1) and SMs (SMR=24.0, 95%CI,13.1–38.2). The probability of living 10 or more yrs was 79.5±1.9%. Multivariate analysis for RD/URD-HCT revealed the risk of late death to be significantly higher in pts receiving TBI (RR=4.4,p<0.001), busulfan (RR=2.8,p=0.03), and those with cGVHD (RR=1.9,p<0.001). Use of cyclosporine (RR=0.5,p<0.001) and methotrexate (RR=0.6,p=0.03) were associated with decreased risk. Among pts receiving A-HCT, the risk of late death was significantly higher in females (RR=1.9,p=0.02). Conclusions: Late mortality rates remain elevated 15 yrs after HCT. Leading causes of death include relapse, pulmonary complications and SMs. No significant financial relationships to disclose.
DETERMINATION OF PROSTAGLANDINS IN BODY FLUIDS AND TISSUES (1979)

Abstract. The biosynthesis of prostaglandins is a very rapid reaction. Since blood platelets, when disturbed, readily convert e. g. arachidonic acid into prostaglandin E 2 and F 2α , those compounds cannot be quantitated in body fluids or tissues which contain platelets. When present in the circulation, primary prostaglandins are rapidly inactivated to corresponding 15‐ke‐to‐13, 14‐dihydro metabolites which occur in plasma in about ten times higher concentrations than the primary prostaglandins. The basal plasma levels of these metabolites are lower than 100 picog/ml. Therefore highly sensitive and specific techniques are necessary for safe quantitation of prostaglandins. The rapid inactivation of prostaglandins also makes it necessary to carefully determine which metabolite should be quantitated in a given experimental situation. The complexity of prostaglandin biochemistry and its importance for accurate monitoring of prostaglandin synthesis in different experimental situations will be discussed in this article.
Controlled Vortex Formation and Facilitated Energy Transfer within Aggregates of Colloidal CdS Nanorods (2015)

Vortex formation is observed in transmission electron microscopy (TEM) images of colloidal CdS nanorod (NR) aggregates. Upon adding polar (poor) solvents into the NR dispersion, the NRs passivated with alkylphosphonic acids start flocculating. When NR clusters are deposited on a TEM grid, the tips of the NRs are immobilized on the substrate, and capillary forces give rise to a net inward tilting as the solvent evaporates, eventually leading to the formation of vortices. Solvent polarity turns out to play a critical role in controlling the structure of vortices. Fluorescence lifetime imaging microscopy (FLIM) of the ensembles reveals that the vortex structures have profound influence on the energy transfer rate within the NR assembly.
Data from Cancer-Testis Antigens and Immunosurveillance in Human Cutaneous Squamous Cell and Basal Cell Carcinomas (2023)

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; Nonmelanoma skin cancer is the most common cancer and comprises basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The incidence of SCC increases drastically in immunosuppressed individuals, suggesting a critical role of the immune system in controlling SCC. To find an explanation for the selective immunosurveillance of SCC, we investigated the expression of cancer-testis (CT) antigens and MHC class I (MHC-I) and the infiltration by immune cells in BCC and SCC.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; We determined the expression of 23 different CT-antigens in 63 BCC and 40 SCC biopsies of immunocompetent and in 20 biopsies of immunosuppressed SCC patients by reverse transcription-PCR and immunohistochemistry. IgG responses to 36 tumor antigens were measured by Western blotting and ELISA. MHC-I expression and CD8&lt;sup&gt;+&lt;/sup&gt; T-cell infiltration were analyzed by immunohistochemistry in BCC and SCC of immunocompetent and immunosuppressed patients and in imiquimod-treated BCC patients.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt; We found expression of at least one CT-antigen in 81% of BCC and in 40% of SCC. We did not detect CT-antigen–specific serum IgG. Most SCC, but not BCC, expressed MHC-I and were infiltrated with CD8&lt;sup&gt;+&lt;/sup&gt; cells. Imiquimod-treated BCC expressed MHC-I and were infiltrated by CD8&lt;sup&gt;+&lt;/sup&gt; T cells.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusions:&lt;/b&gt; We propose that immunosurveillance controls SCC, but not BCC, because the latter lacks MHC-I. This fits with the increased incidence of SCC in immunosuppressed individuals and may explain the relatively low prevalence of CT-antigen expression in SCC as a result of CD8&lt;sup&gt;+&lt;/sup&gt; T-cell–driven immunoediting. Clin Cancer Res; 16(14); 3562–70. ©2010 AACR.&lt;/p&gt;&lt;/div&gt;
CRYSTAL STRUCTURE OF TRIPHENYLTIN ISOPROPYLXANTHATE QUINOLINE N-OXIDE (1995)

The geometry of the tin atom in triphenyltin isopropylxanthate quinoline iV-oxide is a distorted trans-C 3 SnOS trigonal bipyramid (Sn-C = 2.119(3), 2.125(3), 2.128(3), Sn-0 = 2.448(4), Sn-S = 2.544(2) ; O-Sn-S = 167.4(1)). The structure represents an unusual example of a Lewis-acidic sulfidoorganotin compound.
Interaction of the Dopaminergic System With Mechanisms of Associative Learning and Cognition: Implications for Drug Abuse (1999)

The possible role of mechanisms of associative learning in drug abuse and addiction is considered with respect to psychomotor stimulant drugs such as cocaine and amphetamine. Although the initial sites of the reinforcing effects of these drugs are associated with the mesolimbic dopamine projection to the nucleus accumbens, other important neuromodulatory influences are identified. These include the amygdala, which appears to mediate the associative processes by which environmental stimuli come to control drug-seeking behavior. Possible parallel mechanisms by which stimulant drugs enhance effects of aversive as well as rewarding stimuli are discussed. The importance of attribution and context in determining relative rewarding and aversive effects is pointed out. These attributional and contextual factors may be a function of cortical regions that may themselves be impaired by chronic drug abuse, leading to further dysexecutive control over cognition and behavior.
Design of a high temperature oven for an ECR source for the production of uranium ion beams (2007)

VENUS is the superconducting electron cyclotron resonance (ECR) ion source at the Lawrence Berkeley National Lab's 88-Inch Cyclotron. To generate neutral atoms for ionization, the source utilizes a resistively- heated high temperature oven that is located in a magnetic field of up to 4 Tesla and operates at temperatures up to about 2000degC. However, temperatures between 2100- 2300degC are required to produce the desired 280 emuA of high charge state uranium ion beams, and increased thermal and structural effects, combined with elevated chemical reactivity significantly reduce the oven's ability to operate in this envelope. The oven has been redesigned with higher thermal efficiency, improved structural strength and chemically compatible species in order to produce the desired high intensity, high charge state uranium beams. Aspects of the engineering development are presented.
Evaluación de la efectividad del concentrado de complejo de protrombina humana en la recuperación de los parámetros de coagulación en hemorragia crítica. (2021)

espanolObjetivo: El objetivo del estudio fue analizar la efectividad del Concentrado de Complejo de protrombina humana (CCP) en hemorragia critica en dos hospitales espanoles. Metodo: Estudio multicentrico retrospectivo, analitico, observacional llevado a cabo entre enero de 2012 y diciembre de 2018. Variable analizados: datos demograficos, indicacion, marca comercial y dosis del CCP, tratamiento anticoagulante, tratamiento antiagregante, administracion concomitante de vitamina K, tipo de hemorragia, Tiempo de Tromboplastina Parcial Activada (TTPA), tiempo de protrombina (TP), actividad de protrombina(ATP) e INR registrados antes de la administracion del CCP y 24 horas despues de la administracion del CCP, supervivencia a las 24 horas de la administracion del CCP. El analisis estadistico se realizo utilizando la version 1.2 de Jamovi®. Resultados: Se encontraron diferencias estadisticamente significativas (p Conclusiones: En nuestra poblacion de estudio, la administracion de CCP ha demostrado revertir a la normalidad el patron de la coagulacion de la mayoria de los pacientes y un alto porcentaje de supervivencia en hemorragia critica a las 24 horas de la administracion. EnglishObjective: Retrospective, analytical, observational multicenter study carried out between January 2012 and December 2018. Variable analyzed: demographic data, indication, trademark and dose of PCC, anticoagulant treatment, antiplatelet treatment, concomitant administration of vitamin K, type of bleeding, Activated Partial Thromboplastin Time (APTT), prothrombin time (PT), prothrombin activity (ATP) and INR recorded before CCP administration and 24 hours after CCP administration, survival 24 hours after CCP administration. Statistical analysis was performed using Jamovi® version 1.2 Results: Statistically significant differences (p Conclusions: In our study population, the administration of CCP has been shown to revert to normal the coagulation pattern of most patients and a high percentage of survival in critical bleeding 24 hours after administration.
Coherent analysis of argumentative discourse (2003)

R. Cohen (Computational Linguistics, vol.13, no.1-2, p.11-24, 1987) has described a model for the analysis of arguments that includes: (1) a theory of expected coherent structure, which is used to limit analysis to the reconstruction of particular transmission forms; (2) a theory of linguistic clues which assigns a functional interpretation to special words and phrases used by the speaker to indicate the structure of the argument; and (3) a theory of evidence relationships which includes the demand for pragmatic analysis to accommodate beliefs not currently held. The author summarizes the prescriptions for coherent analysis, with a view to their application in the translation of technical material.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Thermodynamic and phylogenetic prediction of RNA secondary structures in the coding region of hepatitis C virus (2002)

The existence and functional importance of RNA secondary structure in the replication of positive-stranded RNA viruses is increasingly recognized. We applied several computational methods to detect RNA secondary structure in the coding region of hepatitis C virus (HCV), including thermodynamic prediction, calculation of free energy on folding, and a newly developed method to scan sequences for covariant sites and associated secondary structures using a parsimony-based algorithm. Each of the prediction methods provided evidence for complex RNA folding in the core- and NS5B-encoding regions of the genome. The positioning of covariant sites and associated predicted stem-loop structures coincided with thermodynamic predictions of RNA base pairing, and localized precisely in parts of the genome with marked suppression of variability at synonymous sites. Combined, there was evidence for a total of six evolutionarily conserved stem-loop structures in the NS5B-encoding region and two in the core gene. The virus most closely related to HCV, GB virus-B (GBV-B) also showed evidence for similar internal base pairing in its coding region, although predictions of secondary structures were limited by the absence of comparative sequence data for this virus. While the role(s) of stem-loops in the coding region of HCV and GBV-B are currently unknown, the structure predictions in this study could provide the starting point for functional investigations using recently developed self-replicating clones of HCV.
Care to Share? (2018)

With mobile devices, users are taking ever-growing numbers of photos every day. These photos are uploaded to social sites such as Facebook and Flickr, often automatically. Yet, the portion of these uploaded photos being publicly shared is low, and on a constant decline. Deciding which photo to share takes considerable time and attention, and many users would rather forfeit the social interaction and engagement than sift through their piles of uploaded photos. In this paper, we introduce a novel task of recommending socially-engaging photos to their creators for public sharing. This will turn a tedious manual chore into a quick, software-assisted process. We provide extensive analysis over a large-scale dataset from the Flickr photo sharing website, which reveals some of the traits of photo sharing in such sites. Additionally, we present a ranking algorithm for the task that comprises three steps:(a) grouping of near-duplicate photos;(b) ranking the photos in each group by their "shareability"; and(c) ranking the groups by their likelihood to contain a shareable photo. A large-scale experiment allows us to evaluate our algorithm and show its benefits compared to competitive baselines and algorithmic alternatives.
Effects of Adenosine on Canine Penile Erection (1992)

We investigated the hemodynamic effects of intracavernous injection of adenosine on canine penile erection. In all ten dogs studied, adenosine induced a dose-dependent increase of intracavernous pressure (ICP). Adenosine (0.67 to 15 micrograms/kg., B.W.) increased arterial blood flow by 83 to 325 percent above baseline levels and also increased venous resistance, which resulted in a full erection (ICP = 80 to 140 cm. H2O) for one to 7 minutes. The repeatability of the adenosine effect was confirmed in eight dogs. We found that adenosine, by virtue of its smooth muscle relaxation properties, can induce a dose-dependent increase of ICP and cause a full erection in dogs.
Implication of repeat insertion domains in the trans-activity of the long non-coding RNA ANRIL (2021)

Long non-coding RNAs have emerged as critical regulators of cell homeostasis by modulating gene expression at chromatin level for instance. Here, we report that the lncRNA ANRIL, associated with several pathologies, binds to thousands of loci dispersed throughout the mammalian genome sharing a 21-bp motif enriched in G/A residues. By combining ANRIL genomic occupancy with transcriptomic analysis, we established a list of 65 and 123 genes potentially directly activated and silenced by ANRIL in trans, respectively. We also found that Exon8 of ANRIL, mainly made of transposable elements, contributes to ANRIL genomic association and consequently to its trans-activity. Furthermore, we showed that Exon8 favors ANRIL's association with the FIRRE, TPD52L1 and IGFBP3 loci to modulate their expression through H3K27me3 deposition. We also investigated the mechanisms engaged by Exon8 to favor ANRIL's association with the genome. Our data refine ANRIL's trans-activity and highlight the functional importance of TEs on ANRIL's activity.
Alternative splicing detection workflow needs a careful combination of sample prep and bioinformatics analysis (2015)

Data, derived from NuGEN v2, were not the ideal input for AltDE, especially when the exon-level approach was used. We observed that both splice variant-quantification and exon-level analysis performances were strongly dependent on the number of input reads. Moreover, the ribosomal RNA depletion protocol was less sensitive in detecting splicing variants, possibly due to the significant percentage of the reads mapping to non-coding transcripts.