gebhart/patrepeval huggingface dataset:
THE CONSEQUENCES OF A RISE IN INTRACELLULAR FREE CA2+ CONCENTRATION INDUCED BY ANTIBODY PLUS COMPLEMENT (1981)

Conference Abstract| April 01 1981 THE CONSEQUENCES OF A RISE IN INTRACELLULAR FREE CA2+ CONCENTRATION INDUCED BY ANTIBODY PLUS COMPLEMENT R. A. Daw; R. A. Daw *Dept.Clin. Biochem., Univ. Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QR Search for other works by this author on: This Site PubMed Google Scholar M. B. Hallett; M. B. Hallett †Dept.Med.Biochem., Welsh Nat. School of Med., Cardiff CF4 4XN Search for other works by this author on: This Site PubMed Google Scholar A. K. Campbell; A. K. Campbell †Dept.Med.Biochem., Welsh Nat. School of Med., Cardiff CF4 4XN Search for other works by this author on: This Site PubMed Google Scholar J. P. Luzio J. P. Luzio *Dept.Clin. Biochem., Univ. Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QR Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1981) 9 (2): 134P. https://doi.org/10.1042/bst009134p Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Cite Icon Cite Get Permissions Citation R. A. Daw, M. B. Hallett, A. K. Campbell, J. P. Luzio; THE CONSEQUENCES OF A RISE IN INTRACELLULAR FREE CA2+ CONCENTRATION INDUCED BY ANTIBODY PLUS COMPLEMENT. Biochem Soc Trans 1 April 1981; 9 (2): 134P. doi: https://doi.org/10.1042/bst009134p Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu nav search search input Search input auto suggest search filter All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1981 Biochemical Society1981 Article PDF first page preview Close Modal You do not currently have access to this content.
Low-temperature characterization of a 1.55-μm multiple-quantum-well laser down to 10 K (2013)

A ridge-waveguide 1.55-&mu;m semiconductor laser with a multiple-quantum-well carrier confinement structure was characterized from room temperature down to 10 K. The temperature dependence of important laser parameters, such as threshold current, series resistance, differential efficiency, and emission wavelength, extracted from standard <i>L-I/I-V</i> measurements, is reported. The applicability of the standard ideal-diode model of semiconductor laser at cryogenic temperatures is analyzed.
On the Properties of the Backstepping Design for Marine Vehicles (2007)

A backstepping control design for marine vehicles was described in [2]. Under a backstepping feedback law, global asymptotic stability of the closed-loop system can be shown under the assumption of unlimited actuation. This paper addresses the issues that arise in the implementation of a backstepping feedback law by saturating actuators. First, for a given backstepping feedback law, an estimate of the domain of attraction is given for the resulting closed-loop system under actuator saturation. A high gain component is then constructed and augmented to the original backstepping feedback law. This additional high gain component is shown not to shrink the estimate of the domain of attraction but possess the ability improve closed-loop response and to reject disturbance.
Double-Negative αβ T Cells Are Early Responders to AKI and Are Found in Human Kidney (2015)

Ischemia-reperfusion injury (IRI) is a major cause of AKI, and previous studies established important roles for conventional CD4(+) T cells, natural killer T cells, and CD4(+)CD25(+)FoxP3(+) Tregs in AKI pathogenesis. We recently identified CD4(-)CD8(-) (double-negative; DN) T cells as an important subset of αβ T cell receptor-positive cells residing in mouse kidney. However, little is known about the pathophysiologic functions of kidney DN T cells. In this study, we phenotypically and functionally characterized murine kidney DN T cells in the steady state and in response to IRI. Unlike CD4(+) and CD8(+) T cells, DN T cells in the steady state expressed high levels of CD69, CD28, and CD40L; differentially expressed IL-27 and IL-10 anti-inflammatory cytokines; spontaneously proliferated at a very high rate; and suppressed in vitro proliferation of activated CD4(+) T cells. Within the first 3-24 hours after IRI, kidney DN T cells expanded significantly and upregulated expression of IL-10. In adoptive transfer experiments, DN T cells significantly protected recipients from AKI by an IL-10-dependent mechanism. DN T cells also made up a large fraction of the T cell compartment in human kidneys. Our results indicate that DN T cells are an important subset of the resident αβ(+) T cell population in the mammalian kidney and are early responders to AKI that have anti-inflammatory properties.
The robots are coming (2015)

How Technological Breakthroughs Will Transform Everyday Life
Robots have the potential to greatly improve the quality of our lives at home, at work, and at play. Customized robots working alongside people will create new jobs, improve the quality of existing jobs, and give people more time to focus on what they find interesting, important, and exciting. Commuting to work in driverless cars will allow people to read, reply to e-mails, watch videos, and even nap. After dropping off one passenger, a driverless car will pick up its next rider, coordinating with the other self-driving cars in a system designed to minimize traffic and wait times—and all the while driving more safely and efficiently than humans.
Combining ElasticFusion with PSPNet for RGB-D Based Indoor Semantic Mapping (2018)

Semantic segmentation has been a research focus of scene parsing and robotic manipulation. And increasing efforts are being made to empower geometry-solely robotic mapping with semantic sensing ability in complex spatial cognition tasks, the so-called semantic mapping. However, semantic mapping has not yet fully exploited the state-of-the-art of semantic segmentation and suffered limitations of application scenario, number of object category and accuracy of object detection. Towards a robust semantic mapping solution, we propose a RGB-D based fusion method that combines an improved ElasticFusion with PSPNet. PSPNet has the potential for breaking restrictions of limited object category in semantic segmentation of RGB images. As for map rendering, the improved ElasticFusion algorithm is validated for its robust performance in indoor scenes in terms of overall model accuracy and integral object shape geometry. Based on the two aforementioned modules, we fuses the semantic images and the depth images to generate 3D point cloud with semantic information. Experiments on the ICL-NUIM datasets have proven the feasibility of the proposed method.
Inhibitors of pyrimidine biosynthesis. Part 2. The synthesis of amidine phosphonates as potential inhibitors of carbamoyl phosphate synthase (1981)

C. J. Wharton and R. Wrigglesworth, J. Chem. Soc., Perkin Trans. 1, 1981, 433 DOI: 10.1039/P19810000433
Relationships between emm and multilocus sequence types within a global collection of Streptococcus pyogenes (2008)

Data indicate that the relationships between emm type and genetic background differ among the three host tissue-related groups, and that the selection pressures acting on emm appear to be strongest for the throat specialists. Since positive selection is likely due in part to a protective host immune response, the findings may have important implications for vaccine design and vaccination strategies.
Modeling and Analysis of Duhem Hysteresis Operators With Butterfly Loops (2023)

In this work, we study and analyze a class of Duhem hysteresis operators that can exhibit butterfly loops. We study first the consistency property of such operator, which corresponds to the existence of an attractive periodic solution when the operator is subject to a periodic input signal. Subsequently, we study the two defining functions of the Duhem operator such that the corresponding periodic solutions can admit a butterfly input–output phase plot. We present a number of examples where the Duhem butterfly hysteresis operators are constructed using two zero-level set curves that satisfy some mild conditions.
Poly(alkyl thiophene-3-carboxylates). Synthesis, properties and electroluminescence studies of polythiophenes containing a carbonyl group directly attached to the ring (1999)

Improved synthetic methodology for poly(3-hexyl- and 3-octyloxycarbonylthiophene-2,5-diyl) (1a and 1b) is reported. n =6700 and 9400 ( w / n =2.5 and 3.2), λ max for fluorescence emission=600 and 610 nm and λ max for electroluminescence=600 and 615 nm, for 1a and 1b respectively. The 1 H NMR spectra required that pentads be considered to explain the spectra. That is the four nearest neighbours to a given ring influence the 1 H NMR spectrum. Electroluminescence efficiencies of 0.016% and 0.018% were observed for devices made from 1a and 1b, respectively. A bilayer device of ITO/poly(3-octylthiophene)/1b/Al emitted at 646 nm, the same wavelength where poly(3-octylthiophene) itself emits. The efficiency was low but was an order of magnitude greater than for poly(3-octylthiophene) itself. Regioregular (HH-TT) poly(4,4′-bis(hexyl- and octyloxycarbonyl)[2,2′-bithiophene]-5,5′-diyl) (3a and 3b) were also prepared via the Ullmann reaction and n =7900 and 11000 respectively. Films of 3a and 3b were yellow in color and showed λ max =377 and 381 nm respectively, about 55-80 nm blue shifted compared with 1a and 1b. This is due to the large rotational barrier in the HH dyads which reduces the effective conjugation length in 3a and 3b. 3a and 3b showed bright fluorescence and electroluminescence with emission of yellow light. Electroluminescence efficiencies were 8.5×10 –3 % and 4.7×10 –3 %, respectively.
Cytotoxic activity, tumor accumulation, and tissue distribution of ruthenium-103-labeled bleomycin. (1981)

Bleomycin (BLM) was labeled with gamma-emitting 103Ru. Yields of 103Ru-labeled BLM as high as 50.6% were attained. 103Ru-labeled BLM was stable in vitro and the 103ru label was not displaced by large excesses of Cu (II) and Co (II) or Fe (III). Chromatography of the urine following 103Ru-labeled BLM injection indicated no in vivo decomposition. Pharmacokinetic studies in healthy inbred SD and tumor-bearing inbred BUF rats demonstrated tumor accumulations, tissue distributions, and clearance nearly identical with those reported for 3H-labeled BLM. Cytotoxicity studies on a WI-L2 human B-cell line showed that BLM labeled with nonradioactive Ru retained 100% of the activity demonstrated by native BLM. Thus BLM may be labeled with isotopes of Ru to form stable complexes by a simple, rapid reaction without loss of its chemotherapeutic properties or variations in its in vivo distribution. BLM labeled with the proper Ru isotope should prove useful as a gamma-emitting tracer for BLM or a beta-emitting compound capable of providing combination chemotherapy and radiotherapy of tumors.
Airway purinergic responses in healthy, atopic nonasthmatic, and atopic asthmatic subjects exposed to ozone (2020)

Ozone exposure triggers airway inflammatory responses that may be influenced by biologically active purine metabolites.
ptRNApred: computational identification and classification of post-transcriptional RNA (2014)

The ptRNApred software is open for public use on http://www.ptrnapred.org/.
Syntheses of 1,3-Imidazoline-2-thione and 2-Phenylimino-1,3-thiazoline Combinatorial Libraries through Different Sequences of the Same Components (2005)

We have developed combinatorial libraries of new 1,3-imidazoline-2-thiones 5 and 2-phenylimino-1,3-thiazolines 7 by way of different reaction sequences of the same three components, gamma-chloroacetoacetanilides 1, amines 2, and isothiocyanates 3 in a parallel synthetic fashion. One of the building blocks, the gamma-chloroacetoacetanilides 1, was prepared by the sequential reaction of 4-methylene-oxetan-2-one (ketene dimer) with chlorine and various anilines. The condensation of 1 with amines gave dihydrofuran 4 intermediates that when reacted with 3 afforded the 1,3-imidazoline-2-thiones 5. On the other hand, reaction of 3 with 2 provided substituted thioureas 6 that were reacted with 1 to yield 2-phenylimino-1,3-thiazolines 7.
Long implosion wire array experiments on the 8-MA Saturn and 20-MA Z accelerators (2003)

Summary form only given, as follows. The quest to reduce the complexity, cost and risk of higher current accelerators drives the need for implosion times that are longer than the canonical 100 ns of present waterline generators. Experiments have been performed at 100 to 200 ns implosion times on the 10-MA Saturn and the 20 MA Z accelerators. These experiments have shown that 7 to 10 ns FWHM pulses can be produced even at the longest implosion times. The experimental data will be presented along with calculations which indicate that stability, uniformity and plasma opacity are critical to determining the radiation efficiency of these implosions.
Increased pH and Seizure Foci Inorganic Phosphate in Temporal Demonstrated by [31P]MRS (1992)

To investigate alterations of brain metabolism associated with temporal lobe epilepsy, [31P]MRS studies were performed on the anterotemporal lobes of patients with medically refractory complex partial seizures. Interictally, the pH was significantly more alkaline in the temporal lobe ipsilateral to the seizure focus (7.25 vs. 7.08, p less than 0.05), and the inorganic phosphorous concentration was greater on the side of the epileptogenic focus (1.9 vs. 1.1 mM, p less than 0.05). These changes in pH and inorganic phosphate may represent metabolic alterations secondary to seizures. Alternatively, because alkalosis enhances neural excitability and may enhance seizure activity, the increased pH of the seizure focus may provide insight into the pathophysiologic mechanism of epileptic seizures.
<title>Predicting and measuring flexural power flow in plates</title> (1996)

Structural power flow is an alternative way of analyzing vibrations, where, differently from traditional techniques, the emphasis is put on the active part of the vibration energy instead of the total. The active vibration energy is directly related to the injection and dissipation of energy in the structure and can, therefore, be a valuable tool for solving vibroacoustical problems. However, measuring the active part of the vibration energy in the presence of a highly reverberant field is often impractical. This paper presents an experimental method especially adapted for the computation of structural power flow using spatially dense vibration data measured with scanning laser Doppler vibrometers. In the proposed method, an operational deflection shape measured over the surface of the structure is curve-fitted using a 2D discrete Fourier series approximation. This approximation minimizes the effects of spatial leakage. From the wavenumber-frequency domain data thus obtained, it is straightforward to compute the spatial derivatives that are necessary to determine the structural power flow. An example consisting of a rectangular aluminum plate supported by four rubber mounts and excited by an electrodynamic shakes is used to appraise the proposed method. Both numerically simulated data and experimental data are used.
Development of a step counting algorithm using the ambulatory tibia load analysis system for tibia fracture patients (2018)

The algorithm reported in this study can assess the ambulatory activity of tibia fracture patients during the recovery period.
ChemInform Abstract: The Role of Molybdenum in the Dissolution and the Passivation of Stainless Steels with Adsorbed Sulfur. (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Navier-Stokes Analysis of Flowfield Characteristics of an Ice-Contaminated Aircraft Wing (2000)

An analytical study was performed as part of the NASA Lewis support of a National Transportation Safety Board (NTSB) aircraft accident investigation. The study was focused on the performance degradation associated with ice contamination on the wing of a commercial turbo-prop-powered aircraft. Based upon the results of an earlier numerical study conducted by the authors, a prominent ridged-ice formation on the subject aircraft wing was selected for detailed flow analysis using 2-dimensional (2-D), as well as, 3-dimensional (3-D) Navier-Stokes computations. This configuration was selected because it caused the largest lift decrease and drag increase among all the ice shapes investigated in the earlier study. A grid sensitivity test was performed to find out the influence of grid spacing on the lift, drag, and associated angle-of-attack for the maximum lift (C(sub lmax)). This study showed that grid resolution is important and a sensitivity analysis is an essential element of the process in order to assure that the final solution is independent of the grid. The 2-D results suggested that a severe stability and control difficulty could have occurred at a slightly higher angle-of-attack (AOA) than the one recorded by the Flight Data Recorder (FDR). This stability and control problem was thought to have resulted from a decreased differential lift on the wings with respect to the normal loading for the configuration. The analysis also indicated that this stability and control problem could have occurred whether or not natural ice shedding took place. Numerical results using an assumed 3-D ice shape showed an increase of the angle at which this phenomena occurred of about 4 degrees. As it occurred with the 2-D case, the trailing edge separation was observed but started only when the AOA was very close to the angle at which the maximum lift occurred.
Topotactic Transformation of Single‐Crystalline Precursor Discs into Disc‐Like Bi2S3 Nanorod Networks (2008)

Abstract Hierarchical, two‐dimensional (2D), disc‐like networks consisting of crossed single‐crystalline Bi 2 S 3 nanorods have been synthesized via a novel 2D‐template‐engaged topotactic transformation process, which involves the formation of intermediate BiOCl single‐crystalline discs and their subsequent chemical transformation into disc‐like Bi 2 S 3 nanofabrics. The transformation process from (001)‐oriented BiOCl discs to disc‐like Bi 2 S 3 nanorod networks has been followed by using scanning electron microscopy (SEM), transmission electron microscopy (TEM), electron diffraction (ED) and X‐ray diffraction (XRD), which revealed that the close matching between the lattice constants of the c ‐axis for orthorhombic Bi 2 S 3 and the a ‐ or b ‐axis for tetragonal BiOCl could be responsible for the preferential growth of [001]‐oriented Bi 2 S 3 nanorods on the top faces of (001)‐oriented BiOCl discs along the two perpendicular [100] and [010] directions of BiOCl. The diameter of the Bi 2 S 3 nanorods involved in the networks can be adjusted by changing the bismuth ion concentration in the reaction solution; moreover, an increase of the HCl concentration would prevent the formation of precursor BiOCl discs, leading to the formation of Bi 2 S 3 nanostructures with varied morphologies. Charge–discharge curves and cyclic voltammograms of the obtained Bi 2 S 3 nanostructures were measured to investigate their electrochemical hydrogen storage behaviors. It was found that the disc‐like Bi 2 S 3 nanorod networks could electrochemically charge and discharge with a capacity of 162 mA h g −1 at room temperature, indicating their potential applications in hydrogen storage, high‐energy batteries, and catalytic fields.
Propagation characteristics of data communication system for protection and disaster relief operations using TV white space (2014)

We are developing a data communication system for protection and disaster relief operations using TV White Space (TVWS) for a disaster rescue robot that works in a prohibited entry area. Such a secondary system operating in TVWS does not harmfully interfere with the primary system of the terrestrial digital broadcast service. The interference from the TVWS device should not exceed I/N of −10 dB in the framework of the Japanese regulations under discussion. This paper presents the propagation characteristics of measurement and simulation in three different locations, estimation based on previous literature, and approximation curves for path loss from the measurement results.
Treatment of cardiac allograft failure by use of an intraaortic axial flow pump. (1990)

Since April 1988 we have used the Hemopump device, a new means of circulatory support, to successfully treat three orthotopic heart transplant recipients with biventricular failure refractory to conventional therapy. The Hemopump device is a 21F catheter-mounted, transvalvular, intraaortic axial flow pump. Power to the pump is percutaneously transmitted from an external electromechanical drive console by a flexible drive cable. We first used the pump in a 61-year-old man in whom severe steroid-resistant rejection developed 28 days after heart transplant, resulting in cardiogenic shock (cardiac index less than 2.0 L/min/m2) despite maximal inotropic support. In the second case a 49-year-old man with no evidence of pulmonary hypertension sustained cardiac arrest 2 hours after heart transplant, necessitating open chest massage and emergency cardiopulmonary bypass. The third patient was a 9-year-old boy in whom rejection developed 5 months after heart transplant, resulting in congestive heart failure that was unresponsive to maximal medical therapy. The device was implanted by way of the femoral artery approach in the first case, the ascending aorta in the second, and the distal abdominal aorta in the third. Duration of support was 46 hours, 65 hours, and 6 days, respectively. Increased blood flow provided by the pump ranged from 2 to 4 L/min. No device-related complications, such as hemolysis, infection, or thromboembolic events, occurred. All patients recovered normal heart function and were weaned from the device. The first patient is well after 12 months. The second patient died of metastatic lymphoma at 2 months, and the third died of Pseudomonas pneumonia after 2 weeks.(ABSTRACT TRUNCATED AT 250 WORDS)
Structural studies on an iron(III) complex containing (Z)-2-(2-aminothiazol-4-yl)-N-(2-hydroxyethyl)-2-(hydroxyimino)acetamide, a model compound for a cephalosporin antibiotic Cefdinir (1996)

(Z)-2-(2-Aminothiazol-4-yl)-N-(2-hydroxyethyl)-2-(hydroxyimino)acetamide (HL) has been employed as a model compound for a cephalosporin antibiotic, Cefdinir. A trinuclear iron(III) complex [Fe3L6]Cl[OH]21 has been obtained from a methanol solution containing HL and FeCl3 and its structure determined by X-ray crystallography: monoclinic, space group P21/n, a= 15.559(1), b= 19.295(2), c= 10.963(1)Å, β= 101.29(1)°, Z= 2. The molecular structure contains a linear Fe(1)–Fe(2)–Fe(1′) arrangement, the central atom Fe(2) being an inversion centre. Atom Fe(1) is co-ordinated to three molecules of L through the thiazole and oximate nitrogen atoms to form Fe(1)L3, and Fe(2) to six oximate oxygen atoms of the two Fe(1)L3 units. The two Fe(1)L3 units are bridged by the central iron atom Fe(2). The Mössbauer spectrum of 1 gave an apparent doublet signal consisting of two doublets, A and B, assigned to Fe(1) and Fe(2), respectively. The isomer shifts δ of these doublets are the same (0.26 mm s–1), and are typical for high-spin iron(III). In addition, the reflectance spectrum did not show any intervalence bands. These spectral data indicate that the three iron atoms are high-spin iron(III). The compound co-ordinates to iron(III)via the thiazole ring nitrogen atom and the oximate nitrogen atom (2N mode) in methanol which is different from that in water, where L prefers to co-ordinate to an iron(III) through the oximate oxygen atom and the amide oxygen atom (2O mode).