gebhart/patrepeval huggingface dataset:
Proton transfer to toluene in H-ZSM-5: TPD, IR, and NMR studies (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTProton transfer to toluene in H-ZSM-5: TPD, IR, and NMR studiesW. E. Farneth, D. C. Roe, T. J. Gricus Kofke, C. J. Tabak, and Raymond J. GorteCite this: Langmuir 1988, 4, 1, 152–158Publication Date (Print):January 1, 1988Publication History Published online1 May 2002Published inissue 1 January 1988https://pubs.acs.org/doi/10.1021/la00079a028https://doi.org/10.1021/la00079a028research-articleACS PublicationsRequest reuse permissionsArticle Views250Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Effect of Metformin on Postprandial Lipemia in Patients With Fairly to Poorly Controlled NIDDM (1994)

Addition of metformin to sulfonylurea-treated patients with NIDDM with less than optimal glycemic control was associated with improved glycemic control, lower postprandial insulin and TG concentrations, and a decrease in postprandial concentration of TG-rich lipoproteins of intestinal origin. All of these changes might be expected to decrease risk of coronary heart disease.
Plasmacytoid myoepithelioma of the palate (1981)

We present the second case of plasmacytoid myoepithelioma of the palate, which was studied by light and electron microscopy. Apart from plasmacytoid cells, some spindle-shaped cells were observed. Both types of neoplastic cells had myoepithelial features, showing abundant 50-80 A thick filaments in the cytoplasm, and exhibited desmosomal junctions. A light cells with less abundant filaments and better equipped with other organelles were observed. Our findings show that there is no clear-cut distinction between the so-called plasmacytoid myoepithelioma and the spindle and stellate myoepithelioma. We suggest that the ultrastructural appearance of these tumors together with the usual histological criteria for malignancy for may be used to evaluate their prognosis.
Chiral γ‐Amino Amide Synthesis by Heterobimetallic Lanthanum/Lithium/Pybox‐Catalyzed Direct Asymmetric Mannich‐Type Reactions of α‐Keto Anilides (2008)

Not so Mannich now: A heterobimetallic La/Li/pybox complex was key in direct catalytic asymmetric Mannich-type reactions, using α-keto anilides as synthetic homoenolate equivalents to afford γ-amino amide products in up to >99 % yield, 95 % ee, and >97:3 syn-selectivity. Stereoselective reduction of the α-keto moiety afforded the β-alkyl-γ-amino-α-hydroxy amide with three contiguous stereocenters (PG=protecting group). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
The Structure of Bypass of Forespore C, an Intercompartmental Signaling Factor during Sporulation in Bacillus (2005)

Sporulation in Bacillus subtilis begins with an asymmetric cell division giving rise to smaller forespore and larger mother cell compartments. Different programs of gene expression are subsequently directed by compartment-specific RNA polymerase sigma-factors. In the final stages, spore coat proteins are synthesized in the mother cell under the control of RNA polymerase containing sigma(K), (Esigma(K)). sigma(K) is synthesized as an inactive zymogen, pro-sigma(K), which is activated by proteolytic cleavage. Processing of pro-sigma(K) is performed by SpoIVFB, a metalloprotease that resides in a complex with SpoIVFA and bypass of forespore (Bof)A in the outer forespore membrane. Ensuring coordination of events taking place in the two compartments, pro-sigma(K) processing in the mother cell is delayed until appropriate signals are received from the forespore. Cell-cell signaling is mediated by SpoIVB and BofC, which are expressed in the forespore and secreted to the intercompartmental space where they regulate pro-sigma(K) processing by mechanisms that are not yet fully understood. Here we present the three-dimensional structure of BofC determined by solution state NMR. BofC is a monomer made up of two domains. The N-terminal domain, containing a four-stranded beta-sheet onto one face of which an alpha-helix is packed, closely resembles the third immunoglobulin-binding domain of protein G from Streptococcus. The C-terminal domain contains a three-stranded beta-sheet and three alpha-helices in a novel domain topology. The sequence connecting the domains contains a conserved DISP motif to which mutations that affect BofC activity map. Possible roles for BofC in the sigma(K) checkpoint are discussed in the light of sequence and structure comparisons.
Migrating existing clinical content from ICD-9 to SNOMED (2010)

Strategies to deal with legacy ICD data must address the issue of codes created by non-taxonomist users. The NLM core subset possibly needs augmentation with concepts from certain SNOMED hierarchies, notably qualifiers, body structures, substances/products and organisms. Concept-matching software needs to utilize query expansion strategies, but these may be effective in production settings only if a large but non-redundant SNOMED subset that minimizes the proportion of extensively pre-coordinated concepts is also available.
Spectroscopic characterization of heterogeneous catalysts (2000)

Transition metal ions - elements with a partially filled d shell - on surfaces of&#13;\ninorganic oxides possess a wide variability in oxidation state, coordination number&#13;\nand molecular structure. This variability forms the basis for their diverse chemical&#13;\nbehavior, which is especially important in the field of heterogeneous catalysis. The&#13;\ncharacterization of supported transition metal ions is a very demanding job, which&#13;\nrequires the use of a battery of advanced preferably in situ spectroscopic techniques.
Faculty Opinions recommendation of The oral microbiome of children: development, disease, and implications beyond oral health. (2019)

In the era of applied meta-omics and personalized medicine, the oral microbiome is a valuable asset. From biomarker discovery to being a powerful source of therapeutic targets, and to presenting an opportunity for developing non-invasive approaches to health care, it has become clear that oral microbes may hold the answer for understanding disease, even beyond the oral cavity. Although our understanding of oral microbiome diversity has come a long way in the past 50 years, there are still many areas that need to be fine-tuned for better risk assessment and diagnosis, especially in early developmental stages of human life. Here, we discuss the factors that impact development of the oral microbiome, and explore oral markers of disease, with a focus on the early oral cavity. Our ultimate goal is to put different experimental and methodological views into perspective for better assessment of early oral and systemic disease at an early age, and discuss how oral microbiomes-at the community level, could provide improved assessment in individuals, and populations at risk.
A Critical Analysis of the Assumptions Underlying the Formulation of Maximum Potential Intensity for Tropical Cyclones (2023)

Abstract Emanuel’s concept of maximum potential intensity (E-PI) estimates the maximum velocity of tropical cyclones from environmental parameters assuming thermal wind (gradient-wind and hydrostatic balances) and slantwise neutrality in the free troposphere. E-PI’s key equation relates proportionally the radial gradients of saturated moist entropy and angular momentum. Here the E-PI derivation is reconsidered to show that the thermal wind and slantwise neutrality imply zero radial gradients of saturation entropy and angular momentum at an altitude where, for a given radius, the tangential wind has a maximum. It is further shown that, while E-PI’s key equation requires that, at the point of maximum tangential wind, the air temperature must increase toward the storm center, the thermal wind equation dictates the opposite. From the analysis of the equations of motion at the altitude of maximum tangential wind in the free troposphere, it is concluded that here the airflow must be supergradient. This implies that the supergradiency factor (a measure of the gradient-wind imbalance) must change in the free troposphere as the airflow tends to restore the balance. It is shown that such a change modifies the derivative of saturation entropy over angular momentum, which cannot therefore remain constant in the free troposphere as E-PI requires. The implications of these findings for the internal coherence of E-PI, including its boundary layer closure, are discussed.
Application of Growth Factors for Enhancement of Mechanical Strength of Grafted Tendon Following Anterior Cruciate Ligament Reconstruction (2011)

Anterior cruciate ligament (ACL) injury is a relatively common knee injury during sports activities A torn ACL usually occurs through a twisting force being applied to the knee whilst the foot is firmly planted on the ground or upon landing The traditional surgical treatment for ACL rupture is ACL reconstruction by an autogenous tendon graft. However, fibroblasts of the tendon graft are necrotized immediately after transplantation of an autogenous tendon graft, and, then, extrinsic fibroblasts infiltrate in the graft During this process, the grafted tendon weakens in the early phase after ACL reconstruction surgery, even if the grafted tendon is subjected in the mechanically physiological condition (Jackson 1991). In addition, a case report of histology of patellar tendon graft 18 months after ACL reconstruction suggested that the cell infiltration into a core portion of the graft occurs very slowly after ligament reconstruction The slow graft maturation may result in graft failure during the postoperative rehabilitation period. It has been known that growth factors enhance proliferation, migration, and matrix synthesis of cells in vitro The authors conducted a series of animal experimental studies for the application of growth factors to ligament reconstruction. We will review our recent experimental studies that intended to enhance mechanical strength of grafted tendon after ligament reconstruction using growth factors.
A Multi-band Solution for Interacting with Energy-Neutral Devices (2021)

RF Wireless Power Transfer (WPT) emerges as a technology for charging autonomous devices, enabling simultaneous power and information transfer. However, with increasing distance, single-input, single-channel rectenna systems are not able to meet the power requirements of large scale IoT applications. In this paper, we tackle this problem on two levels. First, we minimize the energy consumption at the energy-constrained device on three levels. Second, we evolve to a dual-band solution increasing RF WPT. One frequency band is used to provide a base charge to many nodes in a shared transmission. Beam steering, on the other hand, allows for more power hungry operations while introducing as minimal interference as possible. We showcase this method for a hybrid RF-acoustic positioning system. Practical measurements conducted in a multi-antenna indoor testbed (Techtile) show the additional power gain and positioning rate.
Levels of Zinc, Iron, and Copper in Patients with Pseudoexfoliative Cataract (2006)

Purpose To investigate the aqueous humor, lens, and serum concentrations of zinc, iron, and copper in patients with pseudoexfoliative cataract and compare with patients who have senile cataract without Pseudoexfoliation. Methods Twenty-five patients with pseudoexfoliative cataract and 25 patients with senile cataract as control group were enrolled in the study. Samples from aqueous humor, serum, and lens materials during extracapsular cataract extraction (ECCE) were collected from all patients. The levels of selected trace elements in three samples in all groups were assayed with atomic absorption spectrometry (AAS) and statistical analyses were performed with t-test for independent samples except lens zinc and serum copper levels. The data weren't normally distributed, therefore Mann-Whitney U tesf applied for these parameters. Results The zinc and copper levels in aqueous humor of PEX group were significantly higher than those of control group (p&lt;0.001). The iron levels in aqueous humor were not significantly different in PEX group and control group (p=0.252). The copper content of lenses was significantly increased in PEX group compared to control group (p=0.029). The iron and zinc content of lenses had no significant differences between the two groups (p=0.248, p=0.719, respectively). The levels of iron and copper in serum were significantly increased in PEX group compared to control group (p&lt;0.001 and p&lt;0.002, respectively). The zinc level in serum had no significant differences between the two groups (p=0.823, p=0.472, respectively). Conclusions Zinc, iron, and especially copper may play a role in PEX syndrome.
AVO — Current status and the future (1998)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 1998AVO — Current status and the futureAuthors: Richard ArnoldEdward ChiburisRichard ArnoldTexaco Inc. and Edward ChiburisECGEOhttps://doi.org/10.1190/1.1820391 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1820391FiguresReferencesRelatedDetailsCited ByConverted‐wave seismic exploration: MethodsRobert R. Stewart, James E. Gaiser, R. James Brown, and Don C. Lawton17 September 2002 | GEOPHYSICS, Vol. 67, No. 5 SEG Technical Program Expanded Abstracts 1998ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 1998 Pages: 2092 publication data© 1998 Copyright © 1998 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished: 06 Jan 2005 CITATION INFORMATION Richard Arnold and Edward Chiburis, (1998), "AVO — Current status and the future," SEG Technical Program Expanded Abstracts : 248-250. https://doi.org/10.1190/1.1820391 Plain-Language Summary PDF DownloadLoading ...
Benchmarks, Algorithms, and Metrics for Hierarchical Disentanglement (2021)

In representation learning, there has been recent interest in developing algorithms to disentangle the ground-truth generative factors behind a dataset, and metrics to quantify how fully this occurs. However, these algorithms and metrics often assume that both representations and ground-truth factors are flat, continuous, and factorized, whereas many real-world generative processes involve rich hierarchical structure, mixtures of discrete and continuous variables with dependence between them, and even varying intrinsic dimensionality. In this work, we develop benchmarks, algorithms, and metrics for learning such hierarchical representations.
Development of thermographic module for predictive maintenance system of industrial equipment (2020)

The maintenance of industrial equipment extends its useful life, improves its efficiency, reduces the number of failures and increases the safety use. This study proposes to develop a predictive maintenance tool based on infrared thermographic measures capable of anticipating failures in industrial equipment. The thermal response of selected equipment in normal operation and in controlled induced anomalous operation was analyzed. The characterization of these situations enabled the construction of a machine learning system capable of predicting future malfunctions.
Physical and Biological Background of Radiosurgery (2008)

Radiosurgery is a highly precise form of radiation therapy for the treatment of vascular lesions, certain primary or metastatic neoplasms, or functional disorders. Either intracranial or extracranial, which are inaccessible or unsuitable for surgical or other management. As the basis of radiation physics for radiosurgery, this article introduces radiation history, the method of radiation production, interaction mode of radiations with human, transfer of radiation energy to the tissue, and dose planning to generate a desirable dose distribution on the target site. Biologically, the goal of radiosurgery is to cause a precise damage only to the limited tissue within the target volume without exceeding the acceptable rate of complications. As the therapeutic ratio is a function of the volume irradiated, the total dose and dose per fraction used, and the level of acceptable risk, radiation oncologists or practitioners should consider various radiobiologic factors when using radiosurgery to obtain the maximum therapeutic ratio.
Identification of a novel nanomolar inhibitor of hIcmt via a carboxylate replacement approach (2012)

A substrate-based approach to human isoprenylcysteine carboxyl methyltransferase (hIcmt) inhibitors via systematic modulation of both the amide and the prenyl regions of N-acetyl-S-farnesyl-L-cysteine (AFC) led to potent inhibitors of this promising anti-cancer target. However, to date, molecules containing changes to the important carboxylate pharmacophore have not been extensively explored as Icmt inhibitors. We synthesized a set of 39 analogs in which the carboxylate region was chemically redefined using a farnesyl thiopropionic acid (FTPA) backbone. Herein, we demonstrated that modifications of carboxylate motif can lead to potent, sub-micromolar inhibitor of the enzyme. Our most potent inhibitor, analog 12, demonstrated an in vitro IC50 value of 860 nM and cellular effects consistent with hIcmt inhibition.
Production of Justicidin B, a Cytotoxic Arylnaphthalene Lignan from Genetically Transformed Root Cultures of Linum leonii (2006)

Callus and hairy root cultures of Linum leonii were established. The genetic transformation in hairy roots was proven by PCR analysis, which showed integration of rol A and rol C genes into the plant genome. Calli and hairy roots accumulate the arylnaphthalene lignan justicidin B as a major constituent. Hairy roots produce 5-fold higher yields of justicidin B (10.8 mg g(-1) DW) compared to calli. Justicidin B shows strong cytotoxicity on the chronic myeloid leukemia LAMA-8 and K-562 cell lines and on the chronic lymphoid leukemia SKW-3 cell line with IC(50) values of 1.11, 6.08, and 1.62 microM, respectively. Apoptotic properties of justicidin B are reported for the first time.
ChemInform Abstract: SYNTHESIS OF POLYHYDROXYFLAVONOL METHYL ETHERS WITH POTENTIAL CYTOTOXIC ACTIVITY. II. SYNTHESIS OF 6‐HYDROXY‐ AND 8‐HYDROXYKAEMPFEROL DIMETHYL ETHERS S FOR THE STRUCTURE DETERMINATION OF NEW FLAVONOLS FROM BETULA, ALNUS, PARTHENIUM, AND LARREA SPECIES (1977)

Abstract Nach einer modifizierten Algar‐Flynn‐Oyamada‐Reaktion wird das Chalkon (I) oxidativ zu dem Flavon (IIa) cyclisiert, dessen Debenzylierungsprodukt (IIb) zu 4′,6‐ Dimethyl‐6‐hydroxy‐kämpferol ((IIc); Betuletol) demethyliert wird.
Rapid detection of agricultural food crop contamination via hyperspectral remote sensing (2009)

In this study, the authors investigate the use of hyperspectral imaging for food crop monitoring and contamination detection and characterization. The authors investigate the use of a newly developed automated target recognition (ATR) system, that uses a combination of discrete wavelet transforms, multiclassifiers, and decision fusion, to effectively exploit the hyperspectral data to achieve high detection rates while maintaining low false alarm rates. The performance of the proposed hyperspectral ATR system is compared to ATR methods currently used in the remote sensing community, including those based on principal component analysis (PCA), discriminant analysis feature extraction (DAFE), and maximum-likelihood classifiers. The efficacy of both the proposed and conventional hyperspectral analysis methods are evaluated via an extensive 2-year field campaign, consisting of field-level experiments of corn and wheat exposed to highly controlled, varying levels of chemical contaminations. Both handheld and airborne hyperspectral data were collected at multiple times throughout the two growing seasons. The proposed ATR system provided very promising results, indicating the potential of hyperspectral remote sensing as an effective tool for detection and characterization of chemical contaminants in agricultural food crops.
A Noise Tolerant Algorithm For Wrist-mounted Robotic Sensor Calibration With Or Without Sensor Orientation Measurement (2005)

A noise tolerant algorithm for calibration of wrist-mounted robotic sensors is presented. The sensor-wrist calibration can be performed by solving a system of homogeneous transformation equations of the form AiX = XBi, where X is the unknown sensor position relative to the robot wrist, Ai is the ith robot motion, and B; is the ith sensor motion [l-41. A Jacobian relating the measurement residual errors to pose errors of the unknown matrix X is derived. Based on this relationship, X can be iteratively solved. Unlike existing approaches, the algorithm presented here solves kinematic parameters of X in one stage, thus eliminating error propagations and improving noise sensitivities. Moreover, with the proposed algorithm, the parameters of X are observable even when the rotation part of 11; is unknown. This is important in practice since position is easier to measure than orientation. Comparative simulation studies show that the accuracy performance of the iterative algorithm is, in general, better than that of noniterative twostage algorithms, regardless whether the orientation part of Bi is used. The approach presented in this paper also has wide applications for wrist-mounted tool calibration.