gebhart/patrepeval huggingface dataset:
Heritage route along ethnic lines: The case of Penang (2002)

The State of Penang (Negerl Pulau Pinang) is situated in the northern region of the Malaysian Peninsula. It consists of Penang Island (Pulau Pinang) and Province Wellesley (Seberang Peral) on the mainland of Peninsular Malaysia. The island of Penang is connected to the mainland by a 13.5 km bridge, the longest bridge in Asia. The city of Georgetown, the second biggest city in Malaysia, is located on the northeastern cape of the island. The local Malays simply refer to the city as 'Tanjung'.
“Mi” Vico. El héroe del saber (2019)

RESUMEN: "Mi" Vico es el descubridor de una ciencia que no tiene como objeto la historia sino la "naturaleza común de las naciones", y que como
Gigabit optical transmitter GaAs MESFET IC (1987)

A GaAs optical transmitter IC consisting of input buffers, a D-type flip-flop, an NRZ/RZ code convertor and a light source current driver has been developed for use in fibre-optic communication systems, employing D-MESFET SCFL by the Pt buried gate FET process. 1.1 Gbit/s modulation of an LD in RZ format with 20 mA peak drive current has been demonstrated.
Modélisation, reconstruction et suivi pour la reconnaissance de visages (2012)

National audience
Nonextensivity: from low-dimensional maps to Hamiltonian systems (2002)

We present a brief pedagogical guided tour of the most recent applications of nextensive statistical mechanics to well defined nonlinear dynamical systems, ranging from one-dimensional dissipative maps to many-body Hamiltonian systems.
Cardiovascular Health Parameter Changes in Overweight Adolescents Participating in One vs Two Semesters of Physical Education (2007)

The prevalence of high blood pressure & low VO2max is increasing with the number of adolescents at-risk for overweight or overweight. This is an obvious health concern for overweight adolescents, due to the known relationship between cardiovascular fitness & risk of coronary artery disease & stroke. PURPOSE: To assess the effectiveness of two ninth grade physical education (PE) curricula, single semester (SS) vs. two semesters (TS), on cardiovascular health parameters in at-risk for overweight & overweight adolescents. METHODS: Initially there were 276 9th grade PE students (14 ± 1 yrs) that were considered at-risk for overweight or overweight, as determined by BMI, who participated in a SS PE (n=193) or a TS PE (n=83) course. Blood pressure was measured on two separate occasions. Blood pressure was classified as high normal (HN) or hypertensive (HT) based on the CDC growth charts. VO2max was calculated using the Cureton equation (1995). Low VO2max was determined by Fitnessgram norms. RESULTS: The TS group had a 27.2% decrease in at-risk overweight & a 7.7% decrease in overweight adolescents pre to post. The TS males had a 1.5 ml/kg/min increase in VO2max (p=0.0001) but no change occurred in TS females. In the TS group there was a decrease of 23.3% in the frequency of low VO2max. There was no change in TS systolic, diastolic or mean BP. Among TS group the frequency of HN blood pressure decreased by 32.8% & HT increased 34.5%, pre to post. In comparison, the SS group exhibited a decrease of 15.1% in at-risk for overweight & a 14.3% decrease in overweight adolescents pre to post. There was an increase of 1.8 & 1.2 ml/ kg/min in VO2max for both SS males & SS females (p=.0020, p=.0104) respectively. Among SS group the frequency of low VO2max decreased pre to post by 21.6%. In SS group there was an increase in systolic blood pressure of 2.6 mmHg but no change in diastolic or mean blood pressure. In the SS group there was a decrease of 21.4% in the frequency of HN blood pressure as well as a decrease of 39.5% in HT frequency. CONCLUSION: Our data indicates that a TS & SS PE program can significantly increase VO2max. It also indicates that a SS & TS PE may be effective in reducing potentially harmful changes in blood pressure in at-risk for overweight & overweight adolescents. Supported by the Department of Education, Carol White Physical Education Grant.
An enhanced feature detection method for DTV signals (2012)

This paper proposes a robust sensing method for detection of digital TV (DTV) signals. The proposed method exploits the newly discovered features of sliding correlation of DVB-T with its pilot signal for detection: some correlation peaks are observed only having slight difference of amplitudes and, distance between their positions in the sequence of sliding correlation outputs keep constant for different DVB-T timings; moreover, the feature applies for both positive correlation peaks and negative correlation peaks. The method then aggregates the peaks based on their positions and use the aggregation as test statistic; in particular, the aggregations are conducted for positive peaks and negative peaks separately firstly, two aggregation results are then further aggregated for their original values by subtraction. Analysis results show that the proposed method outperforms the conventional one with a slightly increased computational complexity. Computer simulation results further verify that for 2K mode DVB-T, the proposed method reduces sampling time by about 25% for a target sensing performance while increasing computational complexity by around 0.0001%. Hardware test performance further verifies that the proposed method is able to accurately detect ISDB-T at low SNR of −14.5dB, using samples of 8 OFDM symbol durations.
PO195 Outcome measures for duchenne muscular dystrophy: implications for trials (2017)

<h3>Background</h3> The need for deeper understanding of Duchenne muscular dystrophy (DMD) natural history is supported by the rapid advances in translational research, the increase in clinical trials and outcome of recent studies. <h3>Aim</h3> Assess the natural history of DMD through a composite assessment tool encompassing ambulant and non-ambulant phases of the disease. <h3>Methods</h3> Multicentre study (5 centres: London, Newcastle, Paris, Leiden, Nijmegen) with a recruitment target of 80-DMD patients assessed 6-monthly according to a shared protocol. Assessments include 6 min walk distance (6 MWD), NorthStar Ambulatory Assessment (NSAA), Performance of Upper Limb (PUL), MyoSet, FVC and whole body DEXA scan (subgroup). <h3>Results</h3> We analysed longitudinal data for 79 patients, 39 with &gt;24 months follow-up. Ambulant boys&gt;7 years old declined 2.33 points/year in the NSAA (p&lt;0.001). We observed strong correlations between NSAA and timed tests (6 MWD r=0.85,p&lt;0.001; 10 metre run r=−0.87,p&lt;0.001). Non-ambulant boys lost 3.70 PUL scores/year (p&lt;0.001). PUL total had a strong correlation with myogrip (r=0.77,p&lt;0.001), myopinch (r=0.75,p&lt;0.001) and%FVC (r=0.69,p&lt;0.001). All patients with &gt;45% total lean body mass were ambulant. <h3>Conclusion</h3> This on-going study adds to current knowledge on DMD natural history including expected mean changes per year and the relationship between different outcome measures that will contribute to future trial design and interpretation.
<title>Relativistic O-type oscillator-amplifier systems</title> (1990)

An experimental study of a pulsed relativistic electron-beam O-type oscillator driving two O-type amplifiers and operating at levels of a few hundred megawatts in the X-band is reported. Two configurations are examined, in one of which a backward-wave oscillator (BWO) drives two independent traveling-wave amplifiers (TWAs), and in the other of which the same electron beam passes through both the BWO and the TWA structures. Results on power output, pulse distortion, gain, and output matching are presented. The pulse-shortening syndrome and its apparent absence in TWA are briefly discussed.
ICOS expression is required for maintenance but not the formation of germinal centers in the spleen in response to P. yoelii infection (2021)

Abstract Inducible T cell co-stimulator (ICOS) plays a key role in the differentiation and maintenance of follicular helper T (Tfh) cells and thus germinal center (GC) formation. Previously, our lab showed in a Plasmodium chabaudi infection model that Icos -/- mice did not form GCs despite a persistent infection and thus a continued antigen (Ag) load. Here, we show that resolution of a primary infection with P. yoelii , was delayed in Icos -/- mice. This phenotype was associated with a reduction in the accumulation of Tfh-like and GC Tfh cells and an early deficiency in Ag-specific antibody (Ab) production. However, Icos -/- mice maintained their ability to form GCs, though they were less frequent in number than in wild-type (WT) mice. Furthermore, while Ab production in Icos -/- mice matched that of WT mice after the infection cleared, the Abs lacked signs of affinity maturation, suggesting functional defects associated with these GCs. Eventually, these GC structures dissipated more rapidly in Icos -/- mice than in WT mice. Moreover, the ability of Icos -/- mice to form these GC structures is not reliant on the high Ag load associated with P. yoelii infections, as GC formation was preserved in Icos -/- mice treated with early with atovaquone. Finally, mice were unable to form secondary GCs in the absence of ICOS after re-challenge. Overall, these data demonstrate the necessity of ICOS in the maintenance of Tfh cells, the formation and maintenance of sufficient numbers of functioning GCs, and the ability to generate new GC structures after re-infection with P. yoelii .
The Pigments of the Painter Fleury Richard (1777–1852), a Model for Multidisciplinary Study (2022)

Fleury Richard was a colorist painter of the early 19th century. He practiced the oil technique inspired by the Renaissance at a time when advances in chemistry were introducing many new synthetic pigments. His color-mixing cabinet has been kept intact at the Musée des Beaux Arts de Lyon. This original study is based on the analysis of more than 40 color powders using different spectroscopic techniques (X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and Raman spectroscopy), color index estimation, and the comparison of the results obtained from three pictural works painted by the artist. It allows us (i) to identify and reference the pigmented powders and pictural choices in connection with historical manuscripts describing the artist’s practice, and (ii) to identify the most judicious analysis methods and question the difficulty of analyzing paintings in a non-destructive way, where pigments are put into a matrix and mixed.
Contribution of the Gasoline Distribution Cycle to Volatile Organic Compound Emissions in the Metropolitan Area of Mexico City (2002)

Gasoline distribution in the metropolitan area of Mexico City (MAMC) represents an area of opportunity for the abatement of volatile organic compound (VOC) emissions. The gasoline distribution in this huge urban center encompasses several operations: (1) storage in bulk and distribution plants, (2) transportation to gasoline service stations, (3) unloading at service stations' underground tanks, and (4) gasoline dispensing. In this study, hydrocarbon (HC) emissions resulting from breathing losses in closed reservoirs, leakage, and spillage from the operations just listed were calculated using both field measurements and reported emission factors. The results show that the contribution of volatile HC emissions due to storage, distribution, and sales of gasoline is 6651 t/year, approximately 13 times higher than previously reported values. Tank truck transportation results in 53.9% of the gasoline emissions, and 31.5% of emissions are generated when loading the tank trucks. The high concentration of emissions in the gasoline transportation and loading operations by tank trucks has been ascribed to (1) highly frequent trips from distribution plant to gasoline stations, and vice versa, to cope with excessive gasoline sales per gasoline station; (2) low leakproofness of tank trucks; and (3) poor training of employees. In addition, the contribution to HC evaporative and exhaust emissions from the vehicles of the MAMC was also evaluated.
A Concurrent Flow Model for Extraction during Transcapillary Passage (1974)

A model for capillary-tissue exchange in a uniformly perfused organ with uniform capillary transit times and no diffusional capillary interactions was designed to permit the exploration of the influences of various parameters on the interpretation of indicator-dilution curves obtained at the venous outflow following the simultaneous injection of tracers into the arterial inflow. These parameters include tissue geometric factors, longitudinal diffusion and volumes of distribution of tracers in blood and tissue, hematocrit, volumes of nonexchanging vessels and the sampling system, capillary permeability, P . capillary surface area, S , and flow of blood- or solute-containing fluid, F' s . An assumption of instantaneous radial diffusion in the extravascular region is appropriate when intercapillary distances are small, as they are in the heart, or permeabilities are low, as they are for lipophobic solutes. Numerical solutions were obtained for dispersed input functions similar to normal intravascular dye-dilution curves. Axial extravascular diffusion showed a negligible influence at low permeabilities. The "instantaneous extraction" of a permeating solute can provide an estimate of PS/F' s , the ratio of the capillary permeability-surface area product to the flow, when PS/F' s lies between approximately 0.05 and 3.0; the limits of the range depend on the extravascular volume of distribution and the influences of intravascular dispersion. The most accurate estimates were obtained when experiments were designed so that PS/F' s was between 0.2 and 1.0 or peak extractions were between 0.1 and 0.6.
Acute exercise does not improve immune response to HPV vaccination series in adolescents (2019)

• Acute exercise is known to enhance less immunogenic response immunogenic antigens. • In a 3-dose HPV vaccine series, exercise did not change antibody titers. • Potential effects of exercise during first dose in series yet to be examined.
The Efficacy and Safety of Glaucoma Drainage Devices (2007)

The glaucoma drainage devices (GDD) are increasingly popular as the primary procedure over trabeculectomy and cyclo-destructive in the management of refractory glaucoma. Interest in this field is warranted because studies have found significant rates of desirable intraocular pressure (IOP) control as well as maintenance of visual acuity in these difficult cases. GDD have evolved from the first crude attempt, in 1907, using horsehair to drain aqueous from the anterior chamber into the subtenon/conjunctival space at the limbus(). Since then, various materials, such as silk, gold, platinum, tantalum, glass rod, and polythene tube have been used near the limbus and have failed because of conjunctival erosion, implant migration, extrusion as well as scarring. To overcome these problems, current implants were based on the molteno implant, which has a long tube attached to an explant placed 9–10 mm posterior to the limbus. Current GDD are made from various biomaterials, such as acrylic, silicone, and polypropylene, however, their influence on efficacy and safety has not yet been determined.
Mutagenesis by single site-specific arylamine-DNA adducts (1989)

Two related carcinogen adducts, N-(deoxyguanosin-8-yl)-2-aminofluorene (AF) or N-(deoxyguanosin-8-yl)-N-acetyl-2-aminofluorene (AAF), were introduced into the lacZ' gene at base position 6253 of the minus strand of M13mp9 viral DNA. The construction of this site-specifically modified DNA was accomplished by first preparing a gapped heteroduplex missing 7 nucleotides at position 6251-6257 followed by ligation with an unmodified heptamer or with a heptamer containing either an AF or AAF adduct. These site-specifically modified templates were transfected into competent wild-type Escherichia coli cells (JM103) and a uvrA strain (SMH12). The mutation spectrum was determined by phenotypic selection of colorless plaques indicating a defective beta-galactosidase marker enzyme and by an in situ hybridization procedure to detect single base pair mismatches in the adduct region. DNA sequencing was used to characterize 179 of the mutants obtained. We found that both adducts were capable of inducing base substitution mutations at the adduct site and in the local region of the adduct. A specific frameshift (+1G) was also observed at a displaced site. All of the frameshift mutations occurred at the ligation site of the modified oligonucleotide. Control experiments with an unmodified oligonucleotide did not show an enhancement of mutations at this site, indicating that the adducts may have been responsible for these frameshifts. The mutations spectra induced by these adducts suggest that mutagenesis depends not only on adduct structure but also the sequence in which the adduct is located and the host cell type used for mutation expression.
Rapid flow cytometric method for measuring lymphocyte subset activation (1995)

Standard in vitro methods for assessing T-cell activation have typically measured either the proliferative responses of peripheral blood mononuclear cell (PBMC) cultures to various provocative stimuli employing tritiated thymidine incorporation or the secretion of specific cytokines from activated cells. These bulk assay methods suffer the drawback of being lengthy assays, and, in addition, they do not provide information about functional responses of individual lymphocyte subsets. This report describes a three-color flow cytometric method for the rapid analysis (4 hours) of individual T-cell subsets in whole blood responding to various provocative stimuli, including pokeweed mitogen, the comitogenic monoclonal antibodies (mAbs) CD2/CD2R, the superantigen staphylococcal enterotoxin B (SEB), and the specific antigen Candida albicans. After 4 hours, CD69 expression in response to CD2/CD2R paralleled thymidine incorporation measured after 72 hours. Variations in the proportions of CD4+ and CD4- T cells expressing CD69 were observed with different stimuli. These observations demonstrate the potential of multiparameter flow cytometry for the investigation of functional responses of individual T-cell subsets to a variety of stimuli in whole blood.
Alternate Site Glucose Testing: A Crossover Design (2002)

A crossover design study was conducted to determine if reducing pain, by using alternative sites off the finger tip, would increase testing frequency and improve clinical outcome as measured by hemoglobin A1c (HbA1c). Subjects with type 1 and type 2 diabetes tested with the FreeStyle meter (group 1) or tested with their original meter (group 2). After three months the subjects used the alternate meter. Testing frequency and blood glucose concentrations were recorded for the month before the study began and monthly thereafter. HbA1c was tested initially, at the crossover point, and at study conclusion. Insulin users increased testing frequency from 2.4 to 3.0 tests/day. Testing frequency for non-insulin users remained the same at 1.5 tests/day. Testing frequency was the same with the FreeStyle and the original meters. The average HbA1c was 7.4% (SD 1.5%) initially, 7.3% (SD 1.5%) at the crossover point, and 6.9% (SD 1.1%) at study conclusion. There was no significant difference in HbA1c measurements between meter types. Preference rankings were 76% for FreeStyle, 20% for their original meter, and 4% preferred both meters equally. This population tended to be in good glycemic control with 70% having HbA1c at < or = 8.0 at study initiation. Subjects preferred testing with the FreeStyle meter (76%), but did not increase testing frequency. Study participants tended to be in good testing compliance and glycemic control with little room for improvement. A population in poor glucose control might show differences in outcome with off site monitoring.
Linearity Improvement of Microwave FM Oscillators by Harmonic Tuning (1975)

A new linearizing method for microwave communication FM oscillators is presented. As a linearizing mechanism the frequency perturbation caused by tuned harmonic(s) is utilized. Analytical formulation of linearity requirements for the general case are given and explicit relations are delivered for the second harmonic-tuned FM oscillator. Linearity and noise loading results are shown, obtained with an experimental 250-mW X band Gunn diode FM oscillator and satisfying CCIR linearity and noise loading requirements for broad-band microwave radio links.
567 CARDIOVASCULAR SCREENING AND FITNESS ASSESSMENT IN MIDDLE AGED ARMY OFFICERS (1990)

Roloff, J. E.; Zoitick, J. M.; Knapik, J.; Drews, P. R.; Harig, P. T. Author Information
EFFECT OF PAMIDRONATE ON BONE LOSS AND IMPLANT MIGRATION AFTER THA. A 2 YEAR RANDOMISED TRIAL (2003)

Factors that allow the generation or ingression of wear particles at the implant-host interface after total hip arthroplasty (THA) may include early migration and periprosthetic bone loss. We have previously shown that a single 90mg dose of the bisphosphonate pamidronate prevents bone loss over 6 months after THA. In this 2 year randomised trial extension study we assessed the longer term effects of this intervention on bone loss and implant migration. Twenty-two patients received 90mg of pamidronate and 22 received placebo at randomisation 5 days after surgery. Femoral and pelvic bone mineral density (BMD) was measured by dual energy x-ray absorptiometry (DXA) and implant migration was measured using the EBRA-Digital method over a 104 week period. In the placebo group rapid periprosthetic bone loss occurred over the first 6 months. After this period a partial recovery in bone mass occurred in most regions. Patients in the pamidronate group had significantly less femoral, but not pelvic, bone loss than those give placebo (ANOVA P=0.02). Pamidronate was most effective in preventing bone loss in Gruen zones 6 and 7 (ANOVA P=0.004, and P=0.014, respectively). At week 104 the mean total stem migration was 1.77mm±0.27 and 1.62mm±0.37 for the placebo and pamidronate groups, respectively (P>0.05). Total cup migration was 0.75mm±0.26 and 0.76mm±0.14, respectively (P>0.05). Age at surgery accounted for 26% (linear regression r=−0.65, P=0.02) and 38% (r=−0.51, P=0.007) of the variability in stem and cup migration at week 104, with younger subjects experiencing greater migration. Stem migration at week 104 was also inversely related to the Barrack cement mantle grade (r=−0.66, r 2 41%, P=0.0003). Implant migration was not significantly related to changes in periprosthetic bone mass. Pamidronate therapy has a significant effect on bone mass, but not implant stability, after THA.Our findings suggest that the major determinants of early migration after THA are young patient age and poor cementing technique.
Conditions for the Neutralization of Excitation by the Teeth in Epicyclic Gearing (1975)

Excitation of vibration by the teeth in a simple epicyclic gear system is considered, and it is shown that some of the potentially troublesome harmonic components can be neutralized by suitable choice of tooth numbers. In particular, the tooth frequency components acting on the central members are found to be neutralized if the number of teeth on the sun divided by the number of planets ( Z S /n) ≠ integer and ( Z S ± 1)/ n ≠ integer, provided that one of the central members is fixed. The practicability of satisfying the conditions and factors which tend to reduce their effectiveness are discussed.