gebhart/patrepeval huggingface dataset:
ENDOCLIPPING OF A LARGE FEEDING VESSEL TO CECAL AVM TO PREVENT REBLEEDING DURING AGGRESSIVE ANTICOAGULATION TO MAINTAIN CORONARY STENT PATENCY (2004)

Until recently, cauterization was the only endoscopic management option for bleeding cecal AVMs. Ulceration following cauterization could predispose to rebleeding, especially in patients on anticoagulation. We describe the potential role of mechanical hemostasis in the management of bleeding from cecal AVMs in a high risk setting for rebleeding. Case Report: A 73-year-old male with history of CAD and atrial fibrillation on coumadin was admitted with MI. He was started on IV heparin. During hospitalization, he developed hematochezia with a 3 g/dL drop of hemoglobin. An EGD revealed an antral ulcer with a clean base. A colonoscopy revealed a large cecal AVM with a big feeding vessel (fig 1).FigureEndoscopic Clipping of Feeding Vessel: Initally, 4 endoclips were placed on the feeding vessel with the first 2 clips placed away from the AVM; 3rd clip was placed close to the AVM and the last one in between the first two applications. A 4th clip was placed on a fold leading to the AVM (assuming that the fold could contain a draining vessel). Cautery was applied to the AVM after cutting off its blood supply by the application of endoclips to the feeding and draining vessels. Subsequently, the cauterized area was closed with a clip to prevent delayed ulceration and bleeding (fig 2). Follow-up: Capsule endoscopy was normal. He underwent coronary stenting followed by intensive therapy with Plavix and Aspirin and Coumadin to keep the stent patent without any further rebleeding during follow-up (3 mo).FigureConclusions: Mechanical hemostasis with endoclipping of feeding vessel to the cecal AVM has been shown to be useful in this patient who is at high risk of rebleeding from intensive antiplatelet therapy and anticoagulant therapy. [figure 1] [figure 2]
A Comparison in the Efficiency of Six Standard 2-Amino-2-Deoxy-Glucosyl Donors for the Synthesis of (2-Deoxy-2-Phthalimido-β-D-Glucopyranosyl) (1→ 4)-β-D-Glucopyranosides. (1991)

ABSTRACT A systematic study is presented for the most common methods used for the preparation of the disaccharide benzyl O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)-(1→'4)-3,6-di-O-benzoyl-2-deoxy-2-phthalimido-β-D-glucopyranoside (9) from “standard 2-amino-2-deoxyglucopyranosyl donors” 1-6 and benzyl 3,6-di-O-benzoyl-2-deoxy-2-phthalimido-β-D-glucopyranoside (7) as an acceptor. It was found that the highest yield was obtained when the trichloroacetimidate derivative 1 was coupled to the 4 position of acceptor 7. In an analogous manner, the disaccharides allyl O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)-(1→'4)-3,6,-di-O-benzoyl-2-deoxy-2-phthalimido-β-D-glucopyranoside (10), benzyl O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)-(1→'4)-3,6-di-O-benzoyl-2-deoxy-2-phthalimido-β-D-galactopyranoside (12), and allyl O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)-(1→'3)-4,6-O-benzylidene-2-deoxy-2-phthalimido-β-D-glucopyranoside (14) were prepared.
Modeling experiences with full-wave time-domain modeling software (2008)

When evaluating electromagnetic modeling software, there is usually a significant focus on the “accuracy” of the software. Differences between the results generated by the software and the “correct” solution are the result of several potential sources of error including: approximations made in order to represent the actual configuration as a structure that the software can understand; approximations made during the discretization and solution of Maxwell’s equations; and differences between what the modeler wants to analyze and what the software is actually modeling. Of these three potential error sources, the last one is usually the greatest source of error even when the analysis is being done by experienced modelers. In this paper, three full-wave time-domain EM modeling codes are evaluated by analyzing three simple canonical problems. These codes employ the three most common time-domain modeling techniques: the Transmission Line Matrix method (TLM), the Finite Integration Technique (FIT) and the Finite Difference Time Domain technique (FDTD). The three canonical problems are a center-driven dipole, a circuit board power-bus structure, and a power-bus structure with a cable attached. All of the codes are capable of yielding accurate results, but the differences in the specific technique employed and the user interface have a significant effect on the simulation time and the likelihood of getting the correct answer.
Macular star associated with posterior hyaloid detachment (2001)

Vascular damage to the optic disc due to vitreous traction should also be considered as a mechanism for the ophthalmoscopic appearance of the fundus when lesions suggestive of Leber's idiopathic stellate neuroretinitis are present in an adult.
Topical Timolol and the Nursing Mother (1983)

A 34-year-old nursing woman with elevated intraocular pressure voluntarily and without our knowledge applied 0.5% timolol maleate twice daily to her right eye. A milk sample 1.5 hours after administration of drug showed a much higher level of timolol (5.6 ng/mL) than a plasma sample drawn at the same time (0.93 ng/mL). Three control milk specimens showed no measurable levels of timolol. The patient's milk sample 12 hours after her last timolol dose contained 0.5 ng/mL of timolol. On the basis of our calculations, timolol should be used with caution by nursing mothers.
Component-based normalization for the HRRT for sinogram-mode reconstruction (2009)

THE Siemens HRRT scanner is a complex PET tomograph, using 8 LSO/LYSO panel detectors and Depth Of Interaction(DOI) with a total of 119908 detector crystals. The Direct Normalization (DN) is the standard method used for sinogram-mode reconstruction. This paper investigates the use of an improved component-based normalization method for HRRT sinogram reconstruction. This method is originally used for MOLAR LOR listmode reconstruction.Three effects have been identified in the implementation of the original method that caused artifacts and quantification bias in the reconstructed uniformity image. The new CBN method has been implemented that corrects for these effects and produces a uniformity image with the same quality as the DN method. The main effect was the sensitivity drop for LORs with small angles of incidence, which affects all scanners by design.
From Neutral to Anionic η1-Carbon Ligands: Experimental Synthesis and Theoretical Analysis of a Rhodium−Yldiide Complex (2009)

Deprotonation of a cationic rhodium complex of a chelating semistabilized phosphino-phosphonium sulfinyl-ylide ligand afforded the neutral complex of the corresponding yldiide ligand. Despite the limited stability of the yldiide complex its structure was ascertained by ESI MS and multinuclear (1)H, (31)P, (13)C, and (103)Rh NMR spectroscopy. DFT calculations were carried out at the B3PW91/6-31G*/LANL2DZ*(Rh) level to derive a reasonable gas-phase structure for the yldiide complex or model thereof and gain insight into their electronic structure. ELF and AIM topological analyses were used to investigate the metal-ligand bonding and estimate the electron transfer resulting from proton abstraction. ELF weighting of the resonance forms of the anionic "free" yldiide ligand (Ar(3)PC(-)-S(O)Ar) was compared to the corresponding weighting of previously reported neutral counterparts (XCY), namely, bis-alpha-zwitterionic bisylides of phosphonium, sulfonium, or iminosulfonium moieties (X, Y = PR(3), SR(2), S(NMe)R(2)). The results suggest that the phosphonium sulfinylyldiide can be regarded as a tris-alpha,beta-zwitteranionic bisylide (Ar(3)P(+)-C(2-)-S(+)(-O(-))p-Tol).
Modern traversers, turntables and lifting jacks for an efficient and economic maintenance work in railway depots and production workshops (2000)

The paper gives an overview of designs and state of the art concerning turntables, traversers, and lifting jack plants and their importance for manufacturing and maintaining railway vehicles. Two examples from the aircraft industry show solutions that may also be useful for the railway industry. A traverser and a turntable are described from fundamental refurbishment and modernization of an existing plant that can be a reasonable and economic alternative to a new construction. For the covering abstract see ITRD E1252 E125214.
Human Bronchial Epithelial Cells Inhibit Aspergillus fumigatus Germination of Extracellular Conidia via FleA Recognition (2018)

Aspergillus fumigatus is an environmental filamentous fungus that may act as an opportunistic pathogen causing a variety of diseases, including asthma or allergic bronchopulmonary aspergillosis, and infection, ranging from asymptomatic colonization to invasive pulmonary form, especially in immunocompromised patients. This fungus is characterized by different morphotypes including conidia which are the infective propagules able to germinate into hyphae. Due to their small size (2-3 µm), conidia released in the air can reach the lower respiratory tract. The objective of this study was to characterize the interactions between conidia and bronchial epithelial cells. To this end, we studied the role of bronchial epithelial cells, i.e., the BEAS-2B cell line and human primary cells, in conidial germination of a laboratory strain and three clinical strains of A. fumigatus. Microscopic observations and galactomannan measurements demonstrated that contact between epithelial cells and conidia leads to the inhibition of conidia germination. We demonstrated that this fungistatic process is not associated with the release of any soluble components nor internalization by the epithelial cells. We highlight that this antifungal process involves the phosphoinositide 3-kinase pathway on the host cellular side and the lectin FleA on the fungal side. Collectively, our results show that bronchial epithelial cells attenuate fungal virulence by inhibiting germination of extracellular conidia, thus preventing the morphological change from conidia to filaments, which is responsible for tissue invasion.
Regulation of apoptosis in fibroblast‐like synoviocytes by the hypoxia‐induced Bcl‐2 family member Bcl‐2/adenovirus E1B 19‐kd protein–interacting protein 3 (2007)

The proapoptotic protein BNIP-3 is induced in FLS by hypoxia and is widely expressed in RA synovium, but its proapoptotic effects may be inhibited in vivo by proinflammatory cytokines. Since overexpression of BNIP3 in FLS increases apoptosis, this may provide a novel approach for controlling synovial hyperplasia in RA.
Differential activation of transcription versus recombination of transgenic T cell receptor beta variable region gene segments in B and T lineage cells. (1994)

We have tested the ability of the T cell receptor beta (TCR-beta) transcriptional enhancer (E beta) to confer transcriptional activation and tissue-specific V(D)J recombination of TCR-beta V, D, and J segments in a transgenic minilocus recombination substrate. We find that the minimal E beta element, as previously shown for a DNA segment that contained the E mu element, promotes a high level of substrate D to J beta rearrangement in both B and T cells, but only promotes V beta to DJ beta rearrangement in T cells. Thus, both the E mu and E beta elements similarly direct V(D)J recombination of this substrate in vivo, supporting a general role for transcriptional enhancers in the normal regulation of this rearrangement process. Surprisingly, however, we found that both the V beta and DJ beta portion of the constructs were transcribed in an enhancer-dependent fashion (conferred by either E mu or E beta) in both B and T lineage cells, including normal precursor B cells propagated in culture. These findings indicate that, at least in some contexts, transcriptional activation, per se, is not sufficient to confer V(D)J recombinational accessibility to a substrate V gene segment.
Usage of Modified Holt-Winters Method in the Anomaly Detection of Network Traffic: Case Studies (2012)

The traditional Holt-Winters method is used, among others, in behavioural analysis of network traffic for development of adaptive models for various types of traffic in sample computer networks. This paper is devoted to the application of extended versions of these models for development of predicted templates and intruder detection.
Idiopathic Senile Gait Disorders Are Signs of Subclinical Disease (2000)

Senile gait disorders are related to subclinical, perhaps cardiovascular, disease. Senile gait disorders should not be accepted as an inevitable, benign concomitant of the normal aging process.
Oxidative Arylation of Ethylene with Benzene to Produce Styrene (2000)

Abstract Rh complexes were found to work as catalysts for oxidative arylation of ethylene with benzene to produce styrene by addition of acetylacetone and O2 without any oxidizing agent like Cu salt. Vinylacetate was not formed at all in spite of coexistence of acetic acid.
Seven-Year Efficacy of RTS,S/AS01 Malaria Vaccine among Young African Children (2016)

A three-dose vaccination with RTS,S/AS01 was initially protective against clinical malaria, but this result was offset by rebound in later years in areas with higher-than-average exposure to malaria parasites. (Funded by the PATH Malaria Vaccine Initiative and others; ClinicalTrials.gov number, NCT00872963.).
ChemInform Abstract: Metal Sulfonatocalix[4,5]arene Complexes: Bi‐layers, Capsules, Spheres, Tubular Arrays and Beyond (2001)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Primary structure of porcine heart citrate synthase. (1981)

The sequence of 437 amino acid residues of porcine heart citrate synthase [citrate oxaloacetate-lyase (pro-3S-CH2COO leads to acetyl-CoA), EC 4. 1. 3. 7] has been determined by the alignment of fragments generated by cleavage with cyanogen bromide and with trypsin. Isolation of the peptides was facilitated by recent developments in the high-performance liquid chromatography of peptide mixtures. The alignment of these peptides was consistent with that previously deduced from fragments derived by restricted cleavage of citrate synthase by limited proteolysis and cleavage of aspartyl-prolyl bonds and asparaginyl-glycyl bonds. The enzyme contains a modified amino acid, trimethyllysine, at residue 368, showing that the enzyme is subjected to post-translational modification.
In silico characterization of microsatellites in Eucalyptus spp.: abundance, length variation and transposon associations (2005)

This study assessed the abundance of microsatellites, or simple sequence repeats (SSR), in 19 Eucalyptus EST libraries from FORESTs, containing cDNA sequences from five species: E. grandis, E. globulus, E. saligna, E. urophylla and E. camaldulensis. Overall, a total of 11,534 SSRs and 8,447 SSR-containing sequences (25.5% of total ESTs) were identified, with an average of 1 SSR/2.5 kb when considering all motifs and 1 SSR/3.1 kb when mononucleotides were not included. Dimeric repeats were the most abundant (41.03%), followed by trimerics (36.11%) and monomerics (19.59%). The most frequent motifs were A/T (87.24%) for monomerics, AG/CT (94.44%) for dimerics, CCG/CGG (37.87%) for trimerics, AAGG/CCTT (18.75%) for tetramerics, AGAGG/CCTCT (14.04%) for pentamerics and ACGGCG/CGCCGT (6.30%) for hexamerics. According to sequence length, Class II or potentially variable markers were the most commonly found, followed by Class III. Two sequences presented high similarity to previously published Eucalyptus sequences from the NCBI database, EMBRA_72 and EMBRA_122. Local blastn search for transposons did not reveal the presence of any transposable elements with a cut-off value of 10-50. The large number of microsatellites identified will contribute to the refinement of marker-assisted mapping and to the discovery of novel markers for virtually all genes of economic interest.
Ultra-Low Voltage Defect Quantum Cascade Lasers (2009)

We demonstrate a quantum cascade laser featuring a low-voltage-defect short injector. Devices showing a voltage-defect as low as 20meV and voltage efficiency of 88% at 80K are reported, with &gt;80% voltage efficiency at room temperature.
Influence of Injection Time on the Efficiency of Gas Chromatography Columns. (1963)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTInfluence of Injection Time on the Efficiency of Gas Chromatography Columns.Georges. GuiochonCite this: Anal. Chem. 1963, 35, 3, 399–400Publication Date (Print):March 1, 1963Publication History Published online1 May 2002Published inissue 1 March 1963https://pubs.acs.org/doi/10.1021/ac60196a001https://doi.org/10.1021/ac60196a001research-articleACS PublicationsRequest reuse permissionsArticle Views92Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A 2.4 GHz wireless-over-fibre transmitter using a photonic active integrated antenna (PhAIA) (2004)

The integration of a low cost VCSEL with a microstrip antenna results in a low cost wireless-optical transmitter. The VCSEL impedance is matched to that of the antenna and initial microwave link results are shown
Formalisierte Terminologien technischer Systeme und ihrer Zuverlässigkeit (2009)

Während des Lebenslaufs eines technischen Systems kommunizieren Fachleute mit verschiedenen Ausbildungs- und Erfahrungshintergründen miteinander. Nur ein gleiches Verständnis auf der Grundlage eines gemeinsamen Terminologoegebäudes ermöglicht zueinander passendes Handeln. Existierende Ansätze der Terminologiearbeit erfüllen die Ansprüche an eine eindeutige, widerspruchsfreie, präzise, mehrsprachige und domänenübergreifende terminologische Basis allerdings nicht. Um einen reibungslosen Ablauf der gewerkeübergreifenden Zusammenarbeit über den gesamten Lebenslauf technischer Systeme zu ermöglichen, müssen die Grenzfälle und Unschärfen bestehender Terminologieabbildungen gelöst werden. Die in dieser Arbeit ausgearbeitete methodische Grundlage besteht in einer eindeutigen Festlegung von Termini durch die durchgängige Nutzung einheitlicher formaler Beschreibungsmittel. Auf dieser Basis aufbauend wird die Basisterminologie der leittechnischen Modellwelt beschrieben. Sie stellt das Fundament für eine weitergehende Modellbildung dar. Die im Rahmen dieser Arbeit konzipierte Vorgehensweise wird auf die Modellierung eines formalisierten Terminologiegebäudes zur Verlässlichkeit technischer Systeme angewendet. Die einzelnen Termini werden hierbei durch ein Netz zwischen ihnen bestehender Bedeutungsbeziehungen abgebildet und so zu einem neuen Terminologiegebäude zusammengefügt. Gleichwertige Benennungen werden identifiziert und somit ein Beitrag zur Eindeutigkeit des Fachvokabulars geleistet. In dieser Arbeit wird ein Terminologiemanagementsystem konzipiert, welches die Sprache in ihrer Komplexität abzubilden vermag und somit über eine bloße Auflistung von Bezeichnungen und den ihnen zugeordneten Definitionen hinausgeht. Es erlaubt die verteilte Erarbeitung und Abstimmung eines Fachwortschatzes in der Normungsarbeit und in der industriellen Praxis und ermöglicht dort eine fachübergreifende Kommunikation, wo bisher nur Unverständnis, Missverständnis und Ablehnung bestanden.
Functional dopamine D2receptors on rat vagal afferent neurones (1995)

1. In the present study in vitro electrophysiology and receptor autoradiography were used to determine whether rat vagal afferent neurones possess dopamine D2 receptors. 2. Dopamine (10-300 microM) elicited a temperature- and concentration-dependent depolarization of the rat isolated nodose ganglion preparation. When applied to the tissue 15 min prior to agonist, raclopride (10 microM), clozapine (10 microM) or a mixture of raclopride and clozapine (10 microM each) all produced a threefold parallel shift to the right of the dopamine concentration-response curve. In contrast, SCH 23390 (100 nM), phentolamine and propranolol (1 microM each) failed to antagonize the dopamine-mediated depolarization. 3. [125I]-NCQ 298 (0.5 nM), a D2 selective radioligand, bound topographically to sections of rat brainstem. Densitometric quantification of autoradiograms revealed 93.8 +/- 0.5% specific binding of this salicylamide radioligand, as determined by raclopride (10 microM, n = 10 animals). Binding was highest in the nucleus tractus solitarius (NTS), particularly the medial and gelatinous subnuclei. In addition, specific binding was also observed in the interpolar spinal trigeminal nucleus and the inferior olive. 4. Unilateral nodose ganglionectomy caused a 36.6 +/- 3.0% reduction in specific binding in the denervated NTS compared to the contralateral NTS. Furthermore, the loss of binding was confined to the dorsal aspect of the medial subnucleus of the NTS. Sham surgery had no effect on the binding of [125I]-NCQ 298 in rat brainstem. 5. The present data provide evidence for the presence of functionally relevant dopamine D2 receptors on both the soma and central terminals of rat vagal afferent neurones. In addition, the majority of D2 receptors in the rat NTS appear to be located postsynaptically with respect to vagal terminals, and are presumably located either on ascending glossopharyngeal terminals, descending terminals from higher brain regions or on neuronal cell bodies within the NTS.
Proximal Resection Margins: More Prognostic than Distal Resection Margins in Patients Undergoing Hilar Cholangiocarcinoma Resection (2017)

A clear RM, especially proximal RM status, was significant prognosticator, and proximal bile duct resection to the greatest technically feasible extent may be necessary, with careful consideration of the potential morbidity and oncologic outcomes after resection. However, an aggressive approach to obtain a negative distal RM might be controversial and should be considered carefully, depending on the patient's status.
Evaluation of the Automatic Fluorescent Image Analyzer, Image Titer, for Quantitative Analysis of Antinuclear Antibodies (2001)

By making comparisons with the usual manual method, we evaluated an automatic fluorescent image analyzer (Image Titer, Tripath Imaging, Burlington NC), the software for which was developed to simplify measuring indirect immunofluorescent antinuclear antibodies (FANAs). In this new system, images of the stained sample are displayed, and it measures the FANA titer and staining pattern using only 1 slide per subject and does not required the staining of a series of diluted samples as does the manual method. This system showed good reproducibility and linearity for 4 types of control serum samples (with homogeneous, speckled, discrete speckled, and nucleolar staining patterns). In 132 serum samples, consistency between the methods was 100% for the FANA staining pattern and 93.9% for the FANA titer. The Image Titer system detected each pattern in samples with 2 mixed patterns. This system should partly reduce labor and lead to results with minimum differences among individuals, including newly trained persons.