gebhart/patrepeval huggingface dataset:
Data-driven control over short-period internal multiples in media with a horizontally layered overburden (2020)

SUMMARY Short-period internal multiples, resulting from closely spaced interfaces, may interfere with their generating (bandlimited) primaries, and hence they pose a long-standing challenge in their prediction and removal. A recently proposed method based on the Marchenko equation enables removal of the entire overburden-related scattering by means of calculating an inverse transmission response. However, the method relies on time windowing and can thus be inexact in the presence of short-period internal scattering. In this work, we present a detailed analysis of the impact of band-limitation on the Marchenko method. We show the influence of an incorrect first guess, and that adding multidimensional energy conservation and a minimum phase principle may be used to correctly account for both long- and short-period internal multiple scattering. The proposed method can currently only be solved for media with a laterally invariant overburden, since a multidimensional minimum phase condition is not well understood for truly 2-D and 3-D media. We demonstrate the virtue of the proposed scheme with a complex acoustic numerical model that is based on sonic log measurements in the Middle East. The results suggest not only that the conventional scheme can be robust in this setting, but that the ‘augmented’ Marchenko method is superior, as the latter produces a structural image identical to one where the finely layered overburden is missing. This is the first demonstration of a data-driven method to account for short-period internal multiples beyond 1-D.
In - situ generation of Eu2+ in glass forming melts (1998)

We report on the ecacy of in situ reduction of Eu3 to Eu2 in a uoride melt by a variety of chemical reductants and by bulk electrochemical reduction. The Eu2 content of the resultant glasses was determined by a combination of electron paramagnetic resonance and magnetic susceptibility measurements. Addition of LiH, or use of a hydrogen atmosphere, produced near-complete reduction, whilst the electrochemical technique produced approximately 30% conversion. None of the uorozirconate glasses luminesced from Eu2 ions, although a uoroaluminate glass made using the LiH reduction technique did luminesce. O 1999 Elsevier Science B.V. All rights reserved.
Prioritization of autoimmune disease-associated genetic variants that perturb regulatory element activity in T cells (2021)

ABSTRACT Genome-wide association studies have uncovered hundreds of autoimmune disease-associated loci; however, the causal genetic variant(s) within each locus are mostly unknown. Here, we perform high-throughput allele-specific reporter assays to prioritize disease-associated variants for five autoimmune diseases. By examining variants that both promote allele-specific reporter expression and are located in accessible chromatin, we identify 60 putatively causal variants that enrich for statistically fine-mapped variants by up to 57.8-fold. We introduced the risk allele of a prioritized variant (rs72928038) into a human T cell line and deleted the orthologous sequence in mice, both resulting in reduced BACH2 expression. Naïve CD8 T cells from mice containing the deletion had reduced expression of genes that suppress activation and maintain stemness. Our results represent an example of an effective approach for prioritizing variants and studying their physiologically relevant effects.
Ultrawideband measurements for wireless indoor communication systems at 37.2 GHz (2002)

Results of an ultrawideband propagation study are described based on 1 ns impulse response measurements obtained by using a directive horn antenna as a base station in relatively narrow rooms. A brief description of the propagation measurement technique is followed by data analysis using time domain statistical processing. The results are discussed in terms of threshold levels and base station location.
Autonomous mobile patrol system for nuclear power plants: field test report of vehicle navigation and sensor positioning (2002)

The integrity in components of an operating nuclear power plant (NPP) is usually monitored on a daily basis by operator patrols. Currently, there is a pressing need to replace such human patrol activities by systems of automated monitoring in order to reduce radiation exposure and the workload imposed on operators. From this perspective, and under the sponsorship of the Ministry of International Trade and Industry (MITI), we embarked upon a R&D project in 1991 with the objective of developing TOSHIBA Remote Inspection System (TOSRIS) for NPPs. We built a prototype system and examined it in a mockup of a typical NPP environments. This project was completed in 1996. This paper describes the concept of TOSRIS, how the inspection position is calculated, how plans are passed using a 3D-CAD database, and mockup tests.
Polarization Sensitivity of the DAGATA Polarimeter (2010)

In comparison to common Compton Polarimeters the DAGATA (Darmstadt GAmma‐ray Tracking Assembly) polarimeter will significantly enhance the sensitivity for γ‐rays above 4 MeV making use of its large volume 36‐fold segmented HPGe AGATA crystal and the resulting superior position resolution. Results from Monte Carlo Simulations will be presented as well as approaches for data analysis to further improve the sensitivity. Application limits and realistic simulated spectra will be compared to results from existing polarimeters.
Preventing proteostasis diseases by selective inhibition of a phosphatase regulatory subunit (2015)

Protein phosphorylation regulates virtually all biological processes. Although protein kinases are popular drug targets, targeting protein phosphatases remains a challenge. Here, we describe Sephin1 (selective inhibitor of a holophosphatase), a small molecule that safely and selectively inhibited a regulatory subunit of protein phosphatase 1 in vivo. Sephin1 selectively bound and inhibited the stress-induced PPP1R15A, but not the related and constitutive PPP1R15B, to prolong the benefit of an adaptive phospho-signaling pathway, protecting cells from otherwise lethal protein misfolding stress. In vivo, Sephin1 safely prevented the motor, morphological, and molecular defects of two otherwise unrelated protein-misfolding diseases in mice, Charcot-Marie-Tooth 1B, and amyotrophic lateral sclerosis. Thus, regulatory subunits of phosphatases are drug targets, a property exploited here to safely prevent two protein misfolding diseases.
A closed form solution for the internal dynamics of polymer chains. I. Bonds with independent rotational potentials (1990)

An analytical solution to the master equation governing the conformational dynamics of linear polymer chains is formulated. Symmetric chains with N bonds subject to independent rotational potentials are considered. The eigenvalues of the transition rate matrix, which characterize the frequencies of the various relaxation modes, and the corresponding eigenvectors and eigenrows are obtained in closed form. A simple recurrence equation permits one to express the eigenvalues of the N-bond motion in terms of the nonzero eigenvalues associated with the isomeric transitions of single bonds. This leads to a clear understanding of the increase in conformational mobility with N.
Winter flounder antifreeze proteins: a multigene family. (1984)

The nucleotide sequence of a cDNA clone of winter flounder antifreeze protein was determined by the dideoxynucleotide method. The sequence would predict a protein of 91 amino acids composed of a prepropeptide of 38 amino acids and a mature protein of 53 amino acids, which includes four complete 11-amino acid repeats. This predicted sequence corresponds to an antifreeze protein of intermediate size which is one 11-amino acid repeat longer than the smallest antifreeze proteins found in the serum of winter flounder during the cold season. Southern blot hybridization analysis of winter flounder genomic DNA with radioactive cDNA probes reveals a multigene family of potential antifreeze protein genes. This conclusion is supported by amino acid sequence analysis of several serum antifreeze proteins.
Reversible Lability by in Situ Reaction of Self-Assembled Monolayers (2009)

We describe a new methodology for the fabrication of controllably displaceable monolayers using a carboxyl-functionalized self-assembled monolayer and in situ Fischer esterification, a simple and reversible chemical reaction. Using an 11-mercaptoundecanoic acid monolayer as a model system, we show that in situ esterification results in the creation of subtle chemical and structural defects. These defects promote molecular exchange reactions with n-dodecanethiol molecules, leading to the complete and rapid displacement of the exposed areas. Displacement results in well-ordered crystalline n-dodecanethiolate monolayer films. We also show that the complementary hydrolysis reaction can be employed to quench the reacted monolayer, significantly hindering further displacement. The generality of reversible lability was tested by applying the in situ esterification reaction to the structurally distinct carboxyl-functionalized molecule 3-mercapto-1-adamantanecarboxylic acid. Beyond its applicability to create mixed-composition monolayers, this methodology could be combined with chemical patterning techniques, such as microdisplacement printing, to fabricate complex functional surfaces.
Preservation of Force Output Through Progressive Reduction of Stimulation Frequency in Human Quadriceps Femoris Muscle (1990)

The purpose of this study was to determine the effects of a reduction in the pulse frequency on the fatigue rate of human quadriceps femoris muscle during intermittent (8-second) contractions. Twelve healthy subjects each participated in two experimental sessions. Thirty cycles (cycle time: 8 seconds “on”/12 seconds “off”) were applied during each session. During one session, a frequency of 60 pulses per second (pps) was used for all trains. During the other session, the subjects were stimulated with 60 pps for the first train. The stimulating frequency of each train was then progressively reduced, in 5-pps steps, for contractions 2, 3, 5, 8, 12, and 20. By the fifth contraction, the differences in average force produced by the 60-pps trains and the reduced-frequency trains were significant. The difference between the two conditions increased, with the variable-frequency protocol producing 46% more force than the constant-frequency protocol during the last contraction. These results showed that, compared with a constant pulse frequency, reducing the pulse frequency during a fatiguing contraction can markedly decrease the rate of force fatigue of skeletal muscle. This finding suggests that a variable-frequency protocol, similar to the one used in this study, may prove to be a more effective pattern of stimulation for activation of skeletal muscle than the traditionally used constant-frequency protocol.
Efficient GML-native processors for web-based GIS (2006)

Geography Markup Language (GML) is an XML-based language for the markup, storage, and exchange of geospatial data. It provides a rich geospatial vocabulary and allows flexible document structure. However, GML documents are usually large and complicated in structure. Existing techniques for XML document processing, either streaming-based or memory-based, may not deal with such GML documents efficiently. There is an urgent need to adapt existing XML techniques to support the processing of large XML/GML documents, as well as to express GML-native geospatial operations.In this paper, we propose and implement an efficient GML query processor, GPXQuery, and a GML-aware streaming parser, GPSAX, by extending an XQuery processor and a SAX parser, respectively, to support GML-native geospatial functionalities. In addition to these tools, an XML prefiltering technique is applied to the processors to speed up geospatial operations over large GML documents. Our experiment results show that the XML prefiltering technique significantly improves the performance of both the GPXQuery and GPSAX processors by reducing either the query execution time or the memory space consumption. Depending on the nature of user queries, the enhanced query processors can achieve a ten-fold performance improvement. These efficient GML-native processors have been used to develop a GML-based Web GIS with a geospatial query interface and a Scalable Vector Graphics (SVG) map navigator.
Molecular Diagnostic Testing by eyeGENE: Analysis of Patients With Hereditary Retinal Dystrophy Phenotypes Involving Central Vision Loss (2014)

Of the 213 samples, 55 patients (26%) had known causative mutations, and 13 (6%) patients had a VUS that was possibly pathogenic. Overall, selective screening for mutations in BEST1, PRPH2, and ABCA4 would likely yield the highest success rate in identifying the genetic basis for macular dystrophy phenotypes. Because of the overlap in phenotypes between BMD and PD, it would be beneficial to screen genes associated with both diseases.
Atomic structure and optoelectronic properties of inorganic nanotubes (2019)

Resumen del trabajo presentado al Microscopy at the Frontiers of Science Congress Series (MFS), celebrado en el Parque de las Ciencias de Granada (España) del 11 al 13 de septiembre de 2019.
Standards for Studies of Neurological Prognostication in Comatose Survivors of Cardiac Arrest: A Scientific Statement From the American Heart Association (2019)

Significant improvements have been achieved in cardiac arrest resuscitation and postarrest resuscitation care, but mortality remains high. Most of the poor outcomes and deaths of cardiac arrest survivors have been attributed to widespread brain injury. This brain injury, commonly manifested as a comatose state, is a marker of poor outcome and a major basis for unfavorable neurological prognostication. Accurate prognostication is important to avoid pursuing futile treatments when poor outcome is inevitable but also to avoid an inappropriate withdrawal of life-sustaining treatment in patients who may otherwise have a chance of achieving meaningful neurological recovery. Inaccurate neurological prognostication leading to withdrawal of life-sustaining treatment and deaths may significantly bias clinical studies, leading to failure in detecting the true study outcomes. The American Heart Association Emergency Cardiovascular Care Science Subcommittee organized a writing group composed of adult and pediatric experts from neurology, cardiology, emergency medicine, intensive care medicine, and nursing to review existing neurological prognostication studies, the practice of neurological prognostication, and withdrawal of life-sustaining treatment. The writing group determined that the overall quality of existing neurological prognostication studies is low. As a consequence, the degree of confidence in the predictors and the subsequent outcomes is also low. Therefore, the writing group suggests that neurological prognostication parameters need to be approached as index tests based on relevant neurological functions that are directly related to the functional outcome and contribute to the quality of life of cardiac arrest survivors. Suggestions to improve the quality of adult and pediatric neurological prognostication studies are provided.
Understanding and applying precision time protocol (2015)

Precise time synchronization has become a critical component of modern power systems. There are several available methods for synchronizing the intelligent electronic devices (IEDs) in a power system. In recent years, there has been great interest in providing time to the IEDs using the same infrastructure through which the data are communicated. Precision Time Protocol (PTP) is a promising technology for achieving submicrosecond synchronization accuracy between IEDs over Ethernet. This paper presents the protocol fundamentals and discusses considerations for designing power system networks to achieve submicrosecond accuracies. Specific provisions made in the profile for power system applications to support IEC 61850 substation automation systems are also discussed.
An electrochemical immunoassay for prostatic acid phosphatase incorporating enzyme amplification (1989)

The authors have described some of the properties of a simple coulometric enzyme amplified detection method and its application to enzyme immunoassay. This principle has been illustrated with an alkaline phosphatase enzyme label giving rise to NAD + , the catalytic activator for a specific redox cycle which uses the ferricyanide ion as the oxidant. The important features of this system are: high specificty of the redox cycle for NAD + compared with NADP + ; a high turnover number for the alkaline phosphatase/NADP + combination; and a high V max /K m ratio of the alcohol dehydrogenase and diaphorase for NAD + and NADH
Bandwidth allocation of variable bit rate video in ATM networks using radial basis function neural networks (2003)

ATM supports a wide range of multimedia traffic. While ATM provides increased flexibility in supporting various types of traffic the traffic control problems become more difficult to solve when trying to achieve efficient use of network resources. One of such problem is the bandwidth allocation. This paper presents a new approach to the bandwidth allocation problem for video traffic using radial basis functions neural networks (RBFNN). Estimation of an accurate amount of bandwidth to support this traffic has been a challenging task using conventional algorithmic approaches. In this paper, we show that a radial basis function neural network (RBFNN) is capable of learning the non-linear multi-dimentional mapping between different multimedia traffic patterns quality of service (QoS) requirements and the required bandwidth to support each call. Our method employs "on-line" measurements of the traffic count process over a monitoring period which is determined such that the error in estimating the bandwidth is minimized to less than 3% of the actual value. In order to simplify the design of the RBFNN, the input traffic is preprocessed through a low pass filter in order to smooth all high frequency fluctuations. A large set of training data, representing different traffic patterns with different QoS requirements, was used to ensure that RBFNN can generalize and produce accurate results when confronted with new data. The reported results prove that the neurocomputing approach is effective in achieving more accurate results than other traditional methods, based upon mathematical or simulation.
New low-frequency waves and negative mass instability in dusty plasmas (2003)

Low-frequency dusty plasma waves with frequencies much smaller than the frequency of charging collisions of plasma particles with dust particles are considered, taking into account elastic and charging collisions of plasma particles with dust and with neutrals. The usual dust sound waves with an upper frequency equal to the dust plasma frequency are found to be present only for wavelengths much smaller than the plasma particle effective mean free path due to the effective collision frequency. The effective collision frequency is found to be inversely proportional to the square root of the product of the charging frequency and the frequency of particle momentum losses, involving processes due to elastic plasma particle–dust collisions, and collisions with neutrals. It is shown that when the wavelength of the wave is much larger than the mean free path for effective collisions the properties of the waves are different from those previously considered. A negative mass instability is found in this domain of frequencies when the effective mean free path of ions is larger than the effective mean free path of electrons. In the absence of neutrals this appears to be possible only if the temperature of ions exceeds the electron temperature. This can occur in laboratory experiments and space plasmas but not in plasma-etching experiments. In the absence of instability a new dust oscillation, a dust charging mode, is found the frequency of which is almost constant over a certain range of wavenumbers. It is inversely proportional to the dust mass and charging frequency of the dust. A new dust electron sound wave is found for frequencies less than the frequency of the dust charging mode. The velocity of the dust electron sound wave is determined by the electron temperature but not the ion temperatures, as for the usual dust sound waves, with the electron temperature exceeding the ion temperature substantially.
Cooperative induction of 15-lipoxygenase in rheumatoid synovial cells by IL-4 and proinflammatory cytokines. (2004)

We demonstrate that IL-4 cooperated with the inflammatory cytokines IL-1 alpha and TNF alpha to enhance the expression of 15-LOX in rheumatoid synovial cells. Since 15-LOX metabolites have potent anti-inflammatory actions, our data suggest that IL-4 might downregulate rheumatoid inflammation via the induction of 15-LOX and its metabolites.
A novel face recognition for smart glasses (2016)

This paper describes new smart-glass-based face recognition system developed as a benchmark for comparison. Unlike related formulations that limit face recognition to static images captured by smart glasses, our system can also recognize faces in real-time video streams. The system runs face detection on smart glass processing device while offloading the computationally expensive face identification to the network server. We implemented the system on two smart glass platforms: Epson's Moverio (BT-200) and InfoLinker (WUZ-01A) and present the results of their comparative evaluation.
Introductory remarks to session h1, stabilisation (1974)

This paper briefly analyses the following papers: some aspects of the curing of a soil cement (shackel=b and lee=rhf); the behaviour of stabilised soils under simulated traffic loads (shackel=b); cracking in soil cement (george=kp); bitumen stabilisation in Western Australia (brewis=rj).
On spectrum sharing games (2004)

Each access point (AP) in a WiFi network must be assigned a channel for it to service users. There are only finitely many possible channels that can be assigned. Moreover, neighboring access points must use different channels so as to avoid interference. Currently these channels are assigned by administrators who carefully consider channel conflicts and network loads. Channel conflicts among APs operated by different entities are currently resolved in an ad hoc manner or not resolved at all. We view the channel assignment problem as a game, where the players are the service providers and APs are acquired sequentially. We consider the price of anarchy of this game, which is the ratio between the total coverage of the APs in the worst Nash equilibrium of the game and what the total coverage of the APs would be if the channel assignment were done by a central authority. We provide bounds on the price of anarchy depending on assumptions on the underlying network and the type of bargaining allowed between service providers. The key tool in the analysis is the identification of the Nash equilibria with the solutions to a maximal coloring problem in an appropriate graph. We relate the price of anarchy of these games to the approximation factor of local optimization algorithms for the maximum k-colorable subgraph problem. We also study the speed of convergence in these games.