gebhart/patrepeval huggingface dataset:
ChemInform Abstract: Electron Carrier‐mediated Room Temperature Ferromagnetism in Anatase (Ti,Co)O2 (2014)

Abstract Review: 64 refs.
Estimating Recurrence of Spontaneous Preterm Delivery (2009)

Esplin, M. S.; O'Brien, E.; Fraser, A.; Kerber, R. A.; Clark, E.; Simonsen, S. E.; Holmgren, C.; Mineau, G. P.; Varner, M. W. Author Information
Should oncoplastic breast conserving surgery be used for the treatment of early stage breast cancer? Using the GRADE approach for development of clinical recommendations (2021)

This review has revealed a low level of evidence for most of the important outcomes in oncoplastic surgery with lack of any randomized data and absence of standard tools for evaluation of clinical outcomes and especially patients' values. Despite areas of controversy, about one-third (36%) of panel members expressed a strong recommendation in support of oncoplastic BCS. Presumably, this reflects a synthesis of views on the relative complexity of these techniques, associated complications, impact on quality of life and costs.
Utilization of Psychopharmacological Treatment Among Patients With Newly Diagnosed Bipolar Disorder From 2001 to 2010 (2015)

This study presents patterns of pharmacological treatment in patients with newly diagnosed bipolar disorder in Taiwan for a 10-year study period. It would be of importance to further investigate causes and outcomes for polytherapy and nonadherence to psychotropic medications among patients with bipolar disorder.
A Bayesian predictive classification approach to robust speech recognition (2000)

We introduce a new decision strategy called Bayesian predictive classification (BPC) for robust speech recognition where an unknown mismatch between the training and testing conditions exists. We then propose and focus on one of the approximate BPC approaches called quasi-Bayes predictive classification (QBPC). In a series of comparative experiments where the mismatch is caused by additive white Gaussian noise, we show that the proposed QBPC approach achieves a considerable improvement over the conventional plug-in MAP decision rule.
Green synthesis, characterization and biological activities of silver nanoparticles from alkalinized Cymbopogon citratus Stapf (2017)

Silver nanoparticles (AgNPs) have been synthesized from the alkalinized leaf extract of Cymbopogon citratus, also known as lemon grass (LG), and characterized for their size and shape using scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The total formation of the AgNPs was observed visually with a color change from yellow to brownish-black. Fourier transform infrared spectroscopy (FTIR) and energy dispersive x-ray spectroscopy (EDS/EDX) were conducted to determine the various functional groups and the concentration of metal ions in the nanoparticles. The data analysis showed spherically shaped nanoparticles with a size of 10–33 nm, as revealed by TEM, thereby complementing the result for SEM. FTIR identifies the ethylene group as a reducing and capping agent for the formation of the nanoparticles. The x-ray diffraction pattern confirmed the presence of silver crystallites as well as their size, further confirming the result of the TEM. AgNPs do not exhibit very good potential as free radical scavengers when compared to the standards. The synthesized AgNPs in suspension showed activity against both gram-positive and gram-negative bacteria, with minimum inhibitory concentrations (MICs) in the range of 31.25–62.5 µg ml−1. In summary, the synthesized AgNPs possessed an acceptable size and shape.
ChemInform Abstract: Dehydrative Synthesis of Chiral Oxazolidinones Catalyzed by Alkali Metal Carbonates under Low Pressure of CO2. (2013)

Abstract Alkali carbonates such as Cs 2 CO 3 are demonstrated to be efficient catalysts for the synthesis of oxazolidines from chiral aminoalcohols and CO 2 .
An analysis of speeding multicast by acknowledgment reduction technique (SMART) with homogeneous and heterogeneous links - a method of types approach (2011)

We present a novel feedback protocol for wireless broadcast networks that use linear network coding. We consider transmission of packets from a single source to many receivers over a single-hop broadcast erasure channel with heterogeneous links. We propose a predictive model to minimize feedback as well as extraneous data transmissions by the source. The predictive model will schedule feedbacks only when there is a significant probability that all receivers have completed the download. We demonstrate analytically as well as empirically that reliable multicast can provide a good completion time characteristic for all users, if the initial feedback is delayed until the expected download completion time. We show that with SMART, counter to conventional wisdom the average user's download completion time improves slightly as the number of users increases. Furthermore, we show that completion time of the worst user in a multicast session is not very sensitive to the number of users; however it is very sensitive to imbalanced effective rate and heterogeneity among users. Moreover, we show that SMART performs nearly as well as an omniscient transmitter that requires no feedback.
Evolution of technology strategy for surviving high-technology companies (2000)

Thesis (S.M.)--Massachusetts Institute of Technology, System Design & Management Program, 2000.
Silk-Derived Protein Enhances Corneal Epithelial Migration, Adhesion, and Proliferation (2017)

The addition of SDP to culture media significantly enhanced hCLE cell sheet migration, proliferation, and attachment when compared to untreated controls, and indicates SDP's potential utility as an ophthalmic therapeutic agent.
High and Low Energy FAB Tandem Mass Spectrometry of a Series of Anomeric and Regioisomeric 2′-Deoxyribofuranosyl Imidazole Nucleosides (1992)

Abstract Positive ion fast atom bombardment mass spectrometry has aided the structural characterisation of a novel series of anomeric and regioisomeric ethyl 5- and 4-amino-2′ -deoxy-D-erythro-pentofuranosylimidazole-4- and 5 carboxylate nucleosides. Daughter ion MS/MS analyses (high energy MIKE and low energy MS/MS CAD), of the precursor protonated molecular ions for this series of anomeric and regioisomeric nucleosides have provided distinct and reproducible fingerprint patterns which have permitted discrimination between the individual configurations of the various anomers and regioisomers.
Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus (2011)

The guidelines provide specific recommendations that are based on published data or derived from expert consensus. Several analytes have minimal clinical value at present, and their measurement is not recommended.
PLANT LISTS ARE WHERE YOU FIND THEM: A LIST OF LOCAL FLORAS OF MASSACHUSETTS PUBLISHED SINCE 1898 (1960)

(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Growth and optical properties of the novel nonlinear optical crystal NaSr3Be3B3O9F4 (2014)

The new UV nonlinear optical crystal NaSr3Be3B3O9F4 with dimensions up to 13 × 14 × 20 mm3 was successfully grown by the top-seeded solution growth method from LiF–NaF–B2O3 flux for the first time. The crystalline morphological faces are mainly (101), while (021) or (32) faces may occur depending on the direction of the seed applied. The crystalline quality of the as-grown crystal was evaluated by the X-ray rocking curve with the full-width at half-maximum being 0.013°. By a minimum deviation method, the refractive indices are measured from 235 to 2325 nm and fitted by the Sellmeier equations. Furthermore, the hardness, density and chemical stability of the crystal were also reported.
Third Ventriculostomy in Late-onset Idiopathic Aqueductal Stenosis Treatment: A Focus on Clinical Presentation and Radiological Diagnosis (2014)

Endoscopic third ventriculostomy (ETV) is considered the gold standard treatment for obstructive hydrocephalus due to partial or complete obstruction of cerebrospinal fluid (CSF) ventricular pathways caused by mass lesions. However long-term efficacy of this procedure remains controversial as treatment of chronic adult hydrocephalus due to stenosis of Sylvian acqueduct [late-onset idiopathic aqueductal stenosis (LIAS)]. The authors describe clinical presentation, diagnostic investigations in patients affected by LIAS, and define their clinical and radiological outcome after ETV. From January 2003 to December 2008, 13 consecutive LIAS patients treated by ETV were retrospectively reviewed. Pre- and post-operative clinical and radiological findings, including conventional and phase-contrast (PC) cine magnetic resonance imaging (MRI) were investigated. ETV was successfully performed in all patients. Patient's neurological condition improved. No one required a second ETV procedure or shunt implantation. Clinical and radiological results reveal a satisfactory outcome of LIAS patients treated by ETV. At follow-up a clinical improvement could be demonstrated in all cases. Selection criteria of LIAS patients seem to be crucial to obtain satisfactory and long-lasting results. Even in elderly patients with chronic hydrocephalus, ETV can be considered the treatment of choice.
KNAT1 induces lobed leaves with ectopic meristems when overexpressed in Arabidopsis. (1996)

Plant development depends on the activity of apical meristems, which are groups of indeterminate cells whose derivatives elaborate the organs of the mature plant. Studies of knotted1 (kn1) and related gene family members have determined potential roles for homeobox genes in the function of shoot meristems. The Arabidopsis kn1-like gene, KNAT1, is expressed in the shoot apical meristem and not in determinate organs. Here, we show that ectopic expression of KNAT1 in Arabidopsis transforms simple leaves into lobed leaves. The lobes initiate in the position of serrations yet have features of leaves, such as stipules, which form in the sinus, the region at the base of two lobes. Ectopic meristems also arise in the sinus region close to veins. Identity of the meristem, that is, vegetative or floral, depends on whether the meristem develops on a rosette or cauline leaf, respectively. Using in situ hybridization, we analyzed the expression of KNAT1 and another kn1-like homeobox gene, SHOOT MERISTEMLESS, in cauliflower mosaic virus 35S::KNAT1 transformants. KNAT1 expression is strong in vasculature, possibly explaining the proximity of the ectopic meristems to veins. After leaf cells have formed a layered meristem, SHOOT MERISTEMLESS expression begins in only a subset of these cells, demonstrating that KNAT1 is sufficient to induce meristems in the leaf. The shootlike features of the lobed leaves are consistent with the normal domain of KNAT1's expression and further suggest that kn1-related genes may have played a role in the evolution of leaf diversity.
Ultrahigh-pressure experiment with a motor-driven diamond anvil cell (2006)

A Pt sample was compressed to ultrahigh pressures in a diamond anvil cell (DAC) using a motorized gearbox to change pressure remotely from outside the synchrotron x-ray hutch. In situ angle-dispersive x-ray diffraction (XRD) was used to determine pressure from known equations of state (EOS). The sample position was unperturbed during motor-driven pressure changes. By eliminating the need to realign the sample to the x-ray position after each pressure increment, 142 XRD patterns could be collected continuously over the course of three hours, and the maximum pressure of 230 GPa was reached before diamond failure ended the experiment. We demonstrate the advantages of this motor-driven assembly for smooth and efficient pressure change, and the possibility for fine pressure and temporal resolution.
Cytokines Gene Expression Patterns of Bovine Milk During Middle and Late Stages of Lactation (2002)

The cytokine mRNA profiles of the bovine mammary gland were investigated using newly developed TaqMan real-time polymerase chain reaction systems (Applied Biosystems, Foster City, CA, USA). Transcriptional activity of six cytokines, interleukin (IL)-2, IL-6, IL-12, interferon (IFN)-gamma, tumour necrosis factor (TNF)-alpha and granulocyte-macrophage colony stimulating factor (GM-CSF) was studied during the mid- and late-lactation stages. Transcripts for TNF-alpha, GM-CSF, and IFN-gamma were detected in all samples of both stages. However, IL-12 was only detected in 80 and 58 % of late- and mid-lactation samples, respectively. IL-12 expression was up-regulated in late lactation in comparison with the corresponding level in mid-lactation. The cytokines interaction in late lactation was more co-ordinated and their transcriptional levels were significantly correlated among each other, whereas, in mid-lactation significant correlation of the cytokines transcription was only seen with the TNF-alpha, GM-CSF, and IFN-gamma. Cytokine mRNA profiles between mid- and late lactation showed significant differences, which can be attributed to the dramatic changes that the mammary gland is subjected to during late lactation. The significant elevation of IL-12 transcriptional activity in late lactation and its relevance to the mammary gland immunity is discussed.
Supplementary Table and Figure Legend from An Epigenetic Reprogramming Strategy to Resensitize Radioresistant Prostate Cancer Cells (2023)

&lt;p&gt;Legend for Supplementary Tables S1-S5 and Supplementary Figures S1-S10.&lt;/p&gt;
Acquisition of naturally occurring antibody responses to recombinant protein domains of Plasmodium falciparum erythrocyte membrane protein 1 (2008)

Individuals acquire antibodies to surface expressed domains of a highly variant protein. The finding of potential cross-reactivity in responses to one of these domains is an important initial finding in the consideration of potential vaccine targets.
IL-2/B7.1 (CD80) Fusagene Transduction of AML Blasts by a Self-Inactivating Lentiviral Vector Stimulates T Cell Responses in Vitro: a Strategy to Generate Whole Cell Vaccines for AML (2004)

Combined expression of costimulatory factors and proinflammatory cytokines stimulate effective immune-mediated tumor rejection in a variety of murine tumor models. Specifically, syngeneic tumor cells genetically modified to express B7.1 (CD80) have been shown to induce rejection of previously established murine solid tumors, and transduction with IL-2 can further increase survival. However, poor rates of gene transfer and inefficient expression of multiple transgenes encoded by single vectors have hampered the development of such autologous tumor cell vaccines for clinical trials in acute myeloid leukemia (AML) patients. Here we describe the development of a self-inactivating lentiviral vector encoding B7.1 and IL-2 as a single fusion protein postsynthetically cleaved to generate biologically active membrane-anchored B7.1 and secreted IL-2. This enables the efficient transduction of both established and primary AML blasts, resulting in expression of the transgenes in up to 98% of the cells following a single round of infection at an m.o.i. of 10. The combined expression of IL-2 and B7.1 in AML blasts enables increased stimulation of both allogeneic and autologous T cells. The stimulated lymphocytes secrete greater levels of Th1 cytokines and show evidence of specificity, as indicated by their increased proliferation in the presence of autologous AML compared to remission bone marrow cells.
Failure of Hairpin-Ended and Nicked DNA To Activate DNA-Dependent Protein Kinase: Implications for V(D)J Recombination (1998)

V(D)J recombination is initiated by a coordinated cleavage reaction that nicks DNA at two sites and then forms a hairpin coding end and blunt signal end at each site. Following cleavage, the DNA ends are joined by a process that is incompletely understood but nevertheless depends on DNA-dependent protein kinase (DNA-PK), which consists of Ku and a 460-kDa catalytic subunit (DNA-PKCS or p460). Ku directs DNA-PKCS to DNA ends to efficiently activate the kinase. In vivo, the mouse SCID mutation in DNA-PKCS disrupts joining of the hairpin coding ends but spares joining of the open signal ends. To better understand the mechanism of V(D)J recombination, we measured the activation of DNA-PK by the three DNA structures formed during the cleavage reaction: open ends, DNA nicks, and hairpin ends. Although open DNA ends strongly activated DNA-PK, nicked DNA substrates and hairpin-ended DNA did not. Therefore, even though efficient processing of hairpin coding ends requires DNA-PKCS, this may occur by activation of the kinase bound to the cogenerated open signal end rather than to the hairpin end itself.
Nonpolymorphic regions of p190, a protein of the Plasmodium falciparum erythrocytic stage, contain both T and B cell epitopes. (1988)

Two conserved regions from the genetically polymorphic p190 molecule of the malaria parasite Plasmodium falciparum have previously been expressed in Escherichia coli as separate polypeptides (190.L and 190.M) or as a single fusion protein (190.N). In the present study we investigated whether human B and T lymphocytes recognize these conserved regions. The more amino-terminal region, 190.L (corresponding to residues 188-363 of the encoded protein sequence) reacted preferentially with sera from donors living in a malaria-endemic area. Also, EBV-transformed B cells, from a healthy donor living in a malaria-mesoendemic area, were fused with a human-mouse hybrid line (SPM4-0), yielding two hybridomas whose products recognized both 190.L and the fusion protein 190.N, but not the 190.M polypeptide. A large number of p190-specific T cell clones were obtained from PBMC of a noninfected donor, after in vitro stimulation with the recombinant fusion protein 190.N. The clones reacted with intact, parasite-derived p190, as well as either 190.L or 190.M. Four clones that recognized the more amino-terminal fragment also responded to infected E. According to these results the more amino-terminal conserved sequences of p190 have the requisites to be immunogenic in humans.
Optical response of large scale single layer graphene (2011)

We have measured optical transmission and reflection spectra of large scale graphene grown by chemical vapor deposition technique over the extensive frequency range from far-IR to uv (4 meV–6.2 eV). Large scale graphene exhibits an excitonic absorption peak in the uv-region (ℏω=4.6 eV) and the constant interband absorption with σ1(ω)=e2/4ℏ in the IR-visible region, respectively. In the far-IR range, Drude peak is observed, and its strength ωp,2d2 indicates the induced carrier density N2d=1.95×1012 cm−2. These results are highly consistent with the theoretical prediction/experimental results of the single layer graphene. It proves that, contrary to the doubts about its quality due to the chemical growth process, the sample has single layer optical response over the entire photon energy; therefore, it can be applied to large scale devices such as terahertz-IR detector, solar cell material, and visible uv-transparent conductor.
Multi-band impulse filtered UWB signal transmission by wideband optical VCSEL transmitter (2011)

This paper introduces a novel approach for transmitting UWB signals over optical fibre with cost effective Vertical-cavity surface-emitting laser (VCSEL). The transmitted impulse compile with the strict European frequency plan (ECC). A prototype filter is presented with lumped elements which has a -40 dB/500 MHz cut off at the critical 3.1 GHz band. Also a novel impedance matching method is presented for matching low cost 850 nm multi-mode VCSEL in the lower UWB band. Time-domain transmission measurements are presented with the fabricated devices that show this approach is acceptable for low cost remote antenna connection for UWB applications.
Lower Bounds for Two-Sample Structural Change Detection in Ising and\n Gaussian Models (2017)

The change detection problem is to determine if the Markov network structures\nof two Markov random fields differ from one another given two sets of samples\ndrawn from the respective underlying distributions. We study the trade-off\nbetween the sample sizes and the reliability of change detection, measured as a\nminimax risk, for the important cases of the Ising models and the Gaussian\nMarkov random fields restricted to the models which have network structures\nwith $p$ nodes and degree at most $d$, and obtain information-theoretic lower\nbounds for reliable change detection over these models. We show that for the\nIsing model, $\\Omega\\left(\\frac{d^2}{(\\log d)^2}\\log p\\right)$ samples are\nrequired from each dataset to detect even the sparsest possible changes, and\nthat for the Gaussian, $\\Omega\\left( \\gamma^{-2} \\log(p)\\right)$ samples are\nrequired from each dataset to detect change, where $\\gamma$ is the smallest\nratio of off-diagonal to diagonal terms in the precision matrices of the\ndistributions. These bounds are compared to the corresponding results in\nstructure learning, and closely match them under mild conditions on the model\nparameters. Thus, our change detection bounds inherit partial tightness from\nthe structure learning schemes in previous literature, demonstrating that in\ncertain parameter regimes, the naive structure learning based approach to\nchange detection is minimax optimal up to constant factors.\n
Effect of crystallization water on the magnetic properties of crystals composed of complexes of chromium(III) oxalate with spiropyran cations of indoline series (2010)

An increase in the effective magnetic moment and in the widths of the EPR lines of crystals composed of complexes of chromium(III) oxalates with cations of spiropyrans under the action of crystallization water was revealed. It was established that the dehydration-rehydration of the samples is a reversible process. Upon dehydration of the crystals at a temperature above 35°C, the triplet magnetism of the molecules of the spiropyrans weakens, strengthening upon rehydration. The contributions from the chromium oxalate and from the thermally induced states of the spiropyran molecules to the magnetization were isolated. The energies of thermal activation of the triplet states of the spiropyran molecules were determined.
Using Down-Hole Control Valves to Sustain Oil Production From the First Maximum Reservoir Contact, Multilateral and Smart Well in Ghawar Field: Case Study (2007)

This paper describes a case-study detailing planning,&lt;br&gt;completion, testing, and production of the first Maximum&lt;br&gt;Reservoir Contact (MRC), Multilateral (ML) and Smart&lt;br&gt;Completion (SC) deployment in Ghawar Field.
Meta-Stable DIP (MSD) Effect in Fully-Depleted SOI CMOSFETs (2005)

The I-V characteristics and the transconductance of fully depleted MOSFETs can display time-dependent hysteresis when one interface is scanned to or from accumulation, the other interface being in inversion. This new memory effect, called Meta-Stable Dip (MSD), is mainly due to the high carrier lifetime in the silicon film. In this work, we show that the MSD effect can be generalized to several fully depleted technologies. MSD is systematically analyzed for various measurement conditions and devices with different doping including p-MOSFETs, front oxide thickness and silicon film thicknesses.