gebhart/patrepeval huggingface dataset:
A study on low-temperature crystallization of SrBi2Ta2O9 thin films prepared by sol-gel method using steam curing process (1999)

Abstract We have been developing our original hydrolyzed sol-gel coating solutions for the SrBi2Ta2O9 (SBT) thin film. The molecular structure of the solution can be controlled by hydrolysis. We studied the SBT thin film forming process using these coating solutions with the steam curing process used together and observed lower crystallization temperature and improvement of crystal orientation.
Electrical Insulation Performance Comparisons between Kapton and Teflon Coil Insulation Systems for Pulse Power Applications (2008)

Current pulse power alternator windings operate at high current densities and high electromagnetic field levels. Consequently, the winding insulation systems must be designed to withstand high electrical voltage stress and large mechanical loads. Finite element analysis of pulse alternator windings has indicated that good bonding strengths, inter-laminar tensile strength and inter-laminar shear strength, at winding insulation tape interfaces are required to maintain mechanical integrity. These bonding interfaces include the conductor to barrier tape (Teflon or Kapton), barrier tape to barrier tape, barrier tape to glass armor tape, glass armor tape to glass armor tape layers and glass armor tape to composite support structures. Although bonding strength data from adhesive manufacturers is available for bonding metal to metal, bonding strength data for Teflon/Teflon, Kapton/Kapton, Teflon/woven glass and Kapton/woven glass are practically non-existent. Therefore a testing program was developed to determine the mechanical properties of various combinations of barrier tapes and adhesives that were suitable for the high voltage pulse power application. A survey and an evaluation of adhesive properties and performance were conducted to select the prospective adhesives. A total of 11 adhesives were selected and matched with the two prospective barrier tapes: Kapton and Teflon. To further enhance bonding and adhesion, both sides of the tapes were chemically etched. In addition, an evaluation was performed of Teflon tape samples bonded using tapes which came with adhesive on one side with no etching on the opposite side. Multiple samples of all of the candidate barrier tape/adhesive combinations were manufactured and prepared for testing. Testing was performed per specification of ASTM D897 - 01, Standard Test Method for Tensile Properties of Adhesive Bonds. Three rounds of performance testing were conducted to down-select from the initial list of tape-adhesive combinations to the final one tape/adhesive combination that showed the best performance.
Cochannel speaker separation by harmonic enhancement and suppression (1997)

This paper presents a system for separating the cochannel speech of two talkers. The proposed harmonic enhancement and suppression (HES) system is based on a frame-by-frame speaker separation algorithm that exploits the pitch estimate of the stronger talker derived from the cochannel signal. The idea behind this approach is to recover the stronger talker's speech by enhancing their harmonic frequencies and formants given a multiresolution pitch estimate. The weaker talker's speech is obtained from the residual signal created when the harmonics and formants of the stronger talker are suppressed. An automatic speaker assignment algorithm is used to place recovered frames from the target and interfering talkers in separate channels. Automatic speaker assignment performs reasonably well in most cochannel environments, including voiced-on-voiced, voiced-on-unvoiced, unvoiced-on-unvoiced, assignment after processing silence intervals, and single talker speech (no cochannel interference). The HES system has been tested at target-to-interferer ratios (TIRs) from -18 to 18 dB with widely available data bases. It has demonstrated improved performance in keyword spotting tests for TIR values of 6, 12, and 18 dB, and in human listening tests for TIR values of -6 and -18 dB.
Targeted Gene Deletion in <I>Candida albicans</I> Wild-Type Strains by <I>MPA<SUP>R</I></SUP> Flipping (2005)

Many genetic and phenotypic changes occur during the development of drug resistance in fungi. A straightforward approach to assess the contribution of a specific gene to drug resistance is to examine its inactivation in a resistant isolate and to analyze the effect of the mutation on the resistance phenotype. The generation of knockout mutants in the diploid yeast Candida albicans requires two rounds of gene replacement to inactivate both alleles of a target gene. Because auxotrophic markers are not useful for the genetic manipulation of wild-type, clinical isolates, dominant selection markers are required. In this chapter, we describe the MPAR flipping method that combines dominant selection with recombinase-mediated marker recycling for targeted inactivation of specific genes in C. albicans wild-type strains. Using the MPAR flipper makes drug-resistant clinical isolates amenable to genetic manipulation, a prerequisite for the study of causal relationships between specific genes and drug resistance.
Evaluation of a Frequency-Selectable Solid-State Generator for Inductively Coupled Plasma Atomic Emission Spectrometry (1992)

A solid-state rf generator was evaluated as a source for inductively coupled plasma atomic emission spectrometry (ICP-AES). The generator is controlled by a dedicated computer and is capable of sustaining analytical plasmas at either 27.12 or 40.68 MHz at powers up to 2 kW. The analytical performance of this generator was evaluated with particular emphasis on noise and stability. A quartz chimney was used to reduce audio-frequency noise in the ICP emission. Detection limits for 11 different elements and 22 different emision lines were measured when the ICP was sustained alternatively at each generator frequency.
Characterization of a mutation in the acetolactate synthase ofBacillus subtilisthat causes a cold-sensitive phenotype (2007)

The Bacillus subtilis laboratory strain JH642 shows a cold-sensitive phenotype after a temperature shift from 37 to 15 degrees C in comparison to wild type strain MR168. A mutation in the acetolactate synthase complex IlvBH was found to be partially responsible for this growth defect after cold shock. Via DNA sequencing, genetic and biochemical studies, this defect was characterized, which entails a substitution of two adenines to guanines in the ilvB gene. This results in an amino acid substitution from lysine at position 176 to glycine. As a consequence, the acetolactate synthase efficiency in strain JH642 was found to be reduced by 51-fold.
Process based cost modeling (2002)

Presents a method of performing the cost analysis by taking into account the process yield at each step of the process sequence and how the yield at different steps impacts the overall cost of the module. A statistical model of the material process flow is used to estimate assembly costs. The stochastic process models are represented by finite state automata. The material flow modeled represents the hierarchy of material classes (leads, components, and modules). Formal methods to represent the likelihood of a process step and the conversions between the hierarchy of classes are defined. The model is illustrated by examples.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
UAV-Anwendungen im Bergbau - Modellversuche als Beitrag zur photogrammetrischen Forschung und Entwicklung (2018)

Als Grundlage für die fortschreitende Digitalisierung und Automatisierung im Bergbau, kommt der Herstellung von optisch realistischen und hochgenauen 3D Modellen, sowie deren automatischer Interpretation und Weiterverarbeitung, eine besondere Bedeutung zu. Insbesondere für Vermessungs- und Inspektionsanwendungen sind mit Kameras ausgerüstete unbemannte Flugsysteme mittlerweile weit verbreitet und zählen zum aktuellen Stand der Technik. Der größte zukünftige Forschungsbedarf besteht mit Sicherheit in der Datenverarbeitung, wobei einerseits die erreichbare Modellqualität, und andererseits die automatisierte Dateninterpretation für spezielle bergtechnische Fragestellungen wie zum Beispiel die Haufwerkscharakterisierung oder geologische Charakterisierung im Zentrum der Arbeiten steht. Insbesondere aufgrund der möglichen Reproduzierbarkeit, aber auch aufgrund der oft einfacheren Durchführbarkeit nehmen - neben klassischen realmaßstäblichen Untersuchun-gen im Feld - auch Modellversuche derzeit einen gewichtigen Stellenwert in der photogrammetrischen Forschung an der Montanuniversität ein. Im vorliegenden Beitrag werden Beispiele aus der angewandten und grundlagenorientierten Forschung gegeben, wobei der Mehrwert von Laborversuchen, bei gleichzeitiger kritischer Gegenüberstellung mit der Realität, hervorgehoben wird.
Is acupuncture an alternative in idiopathic pain disorder? (1992)

This study investigated the pain-relieving effect of an intensive type of periosteal acupuncture stimulation in patients with idiopathic pain disorder. Twelve patients, 2 males and 10 females, with a mean age of 54, were included in the study. The average duration of their pain was 12.6 years. Each treatment consisted of brief but painful manual stimulation of 3 to 4 periosteal sites. Over a 3-8-month period each patient had between 4-11 treatments, an average of 7. Analgesic drugs that patients were on prior to the study were continued but no other physical or psychological treatment for their pain was applied. Ten patients had either no responses to treatment or only transient responses which were not maintained until the following treatment. Two patients benefitted from treatment, having long periods of substantial pain reduction. All responses were assessed on pain scales maintained daily before and during the entire period of treatments. For the majority (83%) of patients in this study, with an idiopathic pain disorder, periosteal acupuncture stimulation was not a treatment alternative.
Deployment Implications of Reaching the DOE Floating Offshore Wind Shot Goal: A Summary of Initial Results and Methods [Slides] (2023)

The Floating Offshore Wind Shot is an initiative to help usher in a clean energy future by driving U.S. leadership in floating offshore wind design, development, and manufacturing. Here, we document impact of attaining the Shot cost goal of $45/megawatt-hour by 2035, a reduction of 70% from today's cost levels. We find deployment of 90-120 gigawatt of floating offshore wind by 2050.
Na+/H+ antiport in isolated plasma membrane vesicles from the halotolerant alga Dunaliella salina (1986)

Plasma membrane vesicles isolated from the halotolerant alga Dunaliella salina catalyze Na + /H + antiport in a manner that is highly specific for Na + (apparent K m ≅ 16 mM). Li + and amiloride inhibit the process competitively with apparent K i values of 38 and 37 μM, respectively. It is suggested that Na + /H + antiport in this organism plays a major role in maintaining low intracellular Na + concentrations and may also function to drive Na + /HCO 3 − symport, an important step in photosynthetic carbon fixation.
Extending the Depth of Field in a Compound-Eye Imaging System with Super-Resolution Reconstruction (2006)

Optical device miniaturization is highly desirable in many applications. Direct down-scaling of traditional imaging system is one approach, but the extent to which it can be minimized is limited by the effect of diffraction. Compound-eye imaging system, which utilizes multiple microlenses in image capture is a promising alternative. In this paper, we explore the possibility of an incorporation of phase masks in such a system to extend the depth of field. Simulation experiments are conducted to verify the feasibility of the system.
Nanometer scale mechanical properties of gold(111) thin films (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNanometer scale mechanical properties of gold(111) thin filmsM. Salmeron, A. Folch, G. Neubauer, M. Tomitori, D. F. Ogletree, and W. KolbeCite this: Langmuir 1992, 8, 11, 2832–2842Publication Date (Print):November 1, 1992Publication History Published online1 May 2002Published inissue 1 November 1992https://pubs.acs.org/doi/10.1021/la00047a041https://doi.org/10.1021/la00047a041research-articleACS PublicationsRequest reuse permissionsArticle Views171Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A small plasmid in Shigella dysenteriae 1 specifies one or more functions essential for O antigen production and bacterial virulence (1984)

The role of plasmids in the virulence of Shigella dysenteriae 1 W30864, which contains at least five species, was investigated. By means of a standard plasmid-curing procedure, that is, bacterial cultivation at an elevated temperature, five virulence-deficient derivatives were obtained. One of these lacked a small, 6-megadalton plasmid, designated pHW400, exhibited reduced invasiveness for HeLa cells, and failed to produce the somatic antigen. Transposon tagging of the pHW400 plasmid to produce pHW401 and the transfer of this derivative into a variant of strain W30864 lacking pHW400 confirmed the conclusion that the pHW400 plasmid encodes one or more functions involved in O antigen (lipopolysaccharide) biosynthesis and bacterial virulence. A plasmid of similar size was detected in all of the three other strains of S. dysenteriae 1 examined.
Antigenicity of Bovine Pericardium Determined by a Novel Immunoproteomic Approach (2017)

Despite bovine pericardium (BP) being the primary biomaterial used in heart valve bioprostheses, recipient graft-specific immune responses remain a significant cause of graft failure. Consequently, tissue antigenicity remains the principal barrier for expanding use of such biomaterials in clinical practice. We hypothesize that our understanding of BP antigenicity can be improved by application of a combined affinity chromatography shotgun immunoproteomic approach to identify antigens that have previously been overlooked. Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) analysis of affinity chromatography purified antigens resulted in identification of 133 antigens. Most importantly, antigens were identified from all subcellular locations, including 18 integral membrane protein antigens. Critically, isoforms of several protein families were found to be antigenic suggesting the possibility that shared epitope domains may exist. Furthermore, proteins associated with immune, coagulation, and inflammatory pathways were over-represented, suggesting that these biological processes play a key role in antigenicity. This study brings to light important determinants of antigenicity in a clinically relevant xenogeneic biomaterial (i.e. BP) and further validates a rapid, high-throughput method for immunoproteomic antigen identification.
Melody generation system based on a theory of melody sequence (2014)

We propose a melody generation system based on the Implication-Realization Model (IRM) of music theory. The IRM is a music theory, which was proposed by Eugene Narmour. The IRM abstracts music. It then expresses music according to symbol sequences based on information constituting the music pitch, rhythm, and rests. Previous melody generation systems are mostly based on tone transition models, which do not have function of abstracting melodies observed in training data. In those previous systems, generated melodies do not reflect tone sequences that do not exist in training data. However, it is obviously required that a melody generation system is able to abstract melodies in training data and to output certain melody, which is rarely observed in the training data. Our melody generation approach properly abstracts melodies in training data based on the IRM. The IRM expresses contexts of melodies using symbol sequences. Our melody generation system consists of two models; that of symbol sequence transition and that of generating tones from symbols. With the former model, the symbol transition probability model is trained with the results of the IRM analysis. The system then generates an optimal symbol sequence according to the probability model. Then, from a set of tones, each symbol sequence generates a melody. We evaluated the proposed system through subjective human judgment and the results showed that our system properly generated melodies.
Data on the time of integration of the human mitochondrial pseudogenes (NUMTs) into the nuclear genome (2017)

The data and methods presented in this article are supplementing the research article "Integration of mtDNA pseudogenes into the nuclear genome coincides with speciation of the human genus. A hypothesis", DOI: 10.1016/j.mito.2016.12.001 (Gunbin et al., 2017) [1]. Mitochondrial DNA is known to get inserted into nuclear DNA to form NUMTs, i.e. nuclear DNA pseudogenes of the mtDNA. We present here the sequences of selected NUMTs, in which time of integration can be determined with sufficient precision. We report their chromosomal positions , their position within the great ape mtDNA phylogeny, and their times of integration into the nuclear genome. The methods used to generate the data and to control their quality are also presented. The dataset is made publicly available to enable critical or extended analyzes.
A class of deflection-modulated, high-power microwave amplifiers (1977)

An unusual deflection-modulated, fast-wave electron device is analyzed. It has several unique properties; the electron beam is unbunched and is perpendicular to the direction of power flow in the circuit, and the circuit could be a simple fundamental-mode rectangular waveguide. The amplifier consists of an electron gun, a deflection cavity, an optional beam-bending system, and an output interaction region. An idealized theory showing that 100% electronic efficiency may be achieved, and several large-signal calculations with over 90% electronic and circuit efficiencies, are presented. The power, gain, and frequency limits to this type of amplifier or frequency multiplier are discussed. The beam power must be greater than 100 kW for efficient operation because the output circuit losses and deflection power depend on beam voltage, not on beam power. The devices operate best at frequencies below a few gigahertz because of limitations on the ratio of beam size to circuit size. The power gains vary between 10 and 25 dB.
Faculty Opinions recommendation of Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. (2010)

BACKGROUND: Non-small-cell lung cancer with sensitive mutations of the epidermal growth factor receptor (EGFR) is highly responsive to EGFR tyrosine kinase inhibitors such as gefitinib, but little is known about how its efficacy and safety profile compares with that of standard chemotherapy.METHODS: We randomly assigned 230 patients with metastatic, non-small-cell lung cancer and EGFR mutations who had not previously received chemotherapy to receive gefitinib or carboplatin-paclitaxel. The primary end point was progression-free survival; secondary end points included overall survival, response rate, and toxic effects.RESULTS: In the planned interim analysis of data for the first 200 patients, progression-free survival was significantly longer in the gefitinib group than in the standard-chemotherapy group (hazard ratio for death or disease progression with gefitinib, 0.36; P< 0.001), resulting in early termination of the study. The gefitinib group had a significantly longer median progression-free survival (10.8 months, vs. 5.4 months in the chemotherapy group; hazard ratio, 0.30; 95% confidence interval, 0.22 to 0.41; P< 0.001), as well as a higher response rate (73.7% vs. 30.7%, P< 0.001). The median overall survival was 30.5 months in the gefitinib group and 23.6 months in the chemotherapy group (P=0.31). The most common adverse events in the gefitinib group were rash (71.1%) and elevated aminotransferase levels (55.3%), and in the chemotherapy group, neutropenia (77.0%), anemia (64.6%), appetite loss (56.6%), and sensory neuropathy (54.9%). One patient receiving gefitinib died from interstitial lung disease.CONCLUSIONS: First-line gefitinib for patients with advanced non-small-cell lung cancer who were selected on the basis of EGFR mutations improved progression-free survival, with acceptable toxicity, as compared with standard chemotherapy. (UMIN-CTR number, C000000376.)2010 Massachusetts Medical Society PMID: 20573926
Research Notes : United States : A possible interaction between cyt-Y3 and y20-k2 (1984)

Interactions of organelle genomes are a well-documented fact. Interac-tion can take the form of metabolite and energy exchange, co-production of enzyme subunits, and co-production of membrane structural and organizational components (Wallace, 1982). Nucleo-cytoplasmic interaction also has been documented for various traits affecting vegetative and harvest indices (Rob-ertson and Frey, 1984), cytoplasmic male sterility (Levings, 1983), and other agronomic characters (Harvey et al., 1972; Kihara, 1982).
Optical methods and sensors for in situ histology in surgery and endoscopy (2004)

For endoscopic <I>in situ</I> histology, cellular structures have to be imaged non-invasively with sufficient resolution and contrast. Confocal, multi-photon or coherence-gated microscopy are able to reject multiply scattered photons and thus provide sufficient contrast at microscopic resolution. They are the basis for imaging methods such as reflection microscopy, fluorescence microscopy, autofluorescence microscopy, optical coherence microscopy and tomography and multi-photon microscopy, which will be explained and compared. Finally, current concepts for miniaturized optical sensors aiming to implement these imaging methods endoscopically will be presented.