gebhart/patrepeval huggingface dataset:
No evidence for 20th century acceleration in fossil carbon supply to the ocean from thawing permafrost in the Lena River catchment (2019)

Release of carbon from thawing permafrost is a potential positive feedback in a warming climate. Thawing of permafrost is expected to make ancient organic matter bioavailable resulting in increased emissions of greenhouse gases and may also result in increased transport of particulate organic matter through river systems to the ocean. This might have strong effects on near-shore biogeochemistry. Organic matter delivery to the near-shore zone likely has accelerated over the past century in a warming Arctic with increased river discharge leading to increased mobilization of ancient permafrost organic matter. &#13;\nWe studied short sediment cores recovered off two of the main branches of the Lena River Delta, receiving the suspended matter transported from the mainly permafrost covered Lena catchment. The cores were dated using 210Pbxs and 137Cs and cover the past 70 to 120 years. Our compound-specific 14C results for aquatic/marine and terrigenous n-alkanoic acids isolated from the sediments reveal constant age at deposition of the terrigenous biomarkers, while that of the aquatic biomarkers decreased in the most recent decades. Paired with evidence from compound-specific d13C and dD, this suggest a rapid decrease in relative contributions of aquatic/marine-derived compounds, likely through selective degradation, while the source and supply of the terrigenous fraction remained constant in spite of known climatic changes in the hinterland.
Pulsed crossed-beam study of the ionisation of atomic hydrogen by electron impact (1987)

A pulsed crossed-beam technique incorporating time of flight spectroscopy has been successfully developed and applied to measurements of the electron impact ionisation cross sections of atomic hydrogen in the range 14.6-4000 eV. The method has been derived from a crossed-beam coincidence technique. By substituting a pulsed proton beam for the pulsed electron beam in the present work, measured electron impact ionisation cross sections have been normalised by reference to known equivelocity proton impact cross sections for both ionisation and charge transfer. The results resolve the discrepancy between earlier less accurate cross sections measured using the modulated cross-beam technique. They provide a reliable check on the range of validity of theoretical predictions over a wide energy range.
Synthesis of Isothiocyanates as Potential Antineoplastic Agents1,2 (1963)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of Isothiocyanates as Potential Antineoplastic Agents1,2J. H. Burckhalter and Dilbagh S. BarianaCite this: J. Med. Chem. 1963, 6, 2, 203–205Publication Date (Print):March 1, 1963Publication History Published online1 May 2002Published inissue 1 March 1963https://pubs.acs.org/doi/10.1021/jm00338a029https://doi.org/10.1021/jm00338a029research-articleACS PublicationsRequest reuse permissionsArticle Views97Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Formulation of a beam structure with induced strain actuators based on an approximated linear shear stress field (1992)

Many applications based on the implementation of intelligent material systems and structures have employed induced strain actuators as the energy input devices or actuating elements. In order to use the actuation mechanisms of integrated strain actuators effectively, the actuator/substructure coupling effects must be completely understood and modeled accurately. In this paper, a new analytical model refered to as the linear shear stress variation model (LSSVM), is developed based on an approximated through-the-thickness linear shear stress field. The LSSVM captures the physics of the induced stress field that all other existing models have not been able to describe. Closed-form solutions for the entire stresslstrain field distributions as well as the actuation-induced structural behavior are obtained. The formulation of the model is presented in detail in this paper along with an example of its capability.
Quetiapine produces a prolonged reversal of the sensorimotor gating-disruptive effects of basolateral amygdala lesions in rats. (2003)

Prepulse inhibition (PPI) of startle is impaired in schizophrenia and in rats after manipulations of limbic cortical and subcortical regions. The atypical antipsychotic quetiapine was used to reverse PPI deficits after basolateral amygdala (BLA) lesions in rats. BLA quinolinic acid lesions significantly disrupted PPI 1 week postsurgery. Tests with quetiapine (0 vs. 7.5 mg/kg) in a within-subject design 2-3 weeks postsurgery revealed a normalization of PPI. Carry-over effects lasted up to 3 weeks, with a return of lesion-induced deficits by Week 5 postsurgery. This dose of quetiapine also blocked the PPI-disruptive effects of phencyclidine. PPI deficits after BLA lesions are reversed by quetiapine, in a manner that is sustained beyond its acute pharmacological effects and which may be mediated downstream from the BLA.
85. 18F-FDG PET in the staging and management of patients with primary and metastatic renal cell carcinoma (2000)

s: Abstracts of the 30th Annual Scientific Meeting of the Australian and New Zealand Society of Nuclear Medicine
Platinum-Maghemite Core−Shell Nanoparticles Using a Sequential Synthesis (2003)

Pt@Fe2O3 core−shell nanoparticles have been made using a sequential synthetic method. Platinum nanoparticles were synthesized via reduction of platinum acetylacetonate in octyl ether, and layers of iron oxide were subsequently deposited on the surface of Pt nanoparticles through thermal decomposition of iron pentacarbonyl. The core−shell nanoparticles were characterized by powder X-ray diffraction, high-resolution transmission electron microscopy, and X-ray photoemission spectroscopy. Thickness of the shell can be controlled by changing concentrations of the reactants and the reaction conditions. These Pt@Fe2O3 core−shell nanoparticles could have potential applications in catalysis and as precursors for making property-tunable magnetic nanoparticles, thin films, and nanocomposites.
Self-Calibrating Continuous-Time Equalization Targeting Inter-symbol Interference (2006)

A method for designing self-calibrating continuous-time equalizers is proposed. An error term, generated from the channel pulse response may be used to adaptively calibrate the equalizer, resulting in a significant reduction of ISI. This error term is based on the minimization of accumulating ISI versus total ISI. By limiting the change in ISI from bit to bit, reasonable voltage and timing margins are achieved. Matlab simulations show the clear opening of a 20Gbps data eye at the end of a 6" copper trace on an FR4-based PC board
Catalytic Hydrosilylation of Diarylalkynes by Layer-Segregated Platinum−Ruthenium Cluster Complexes Pt3Ru6(CO)20(μ3-RC2R)(μ3-H)(μ-H) (1998)

It has been found that the layer-segregated platinum−ruthenium cluster complex Pt3Ru6(CO)20(μ3-PhC2Ph)(μ3-H)(μ-H), 2a, is an effective catalyst for the hydrosilylation of diphenylacetylene by triethylsilane to yield (E)-[(1,2-diphenyl)ethenyl]triethylsilane at a turnover frequency, TOF (TON/h), of 29 h-1. The activation parameters, ΔH ⧧ = 17(2) kcal/mol and ΔS ⧧ = −18(5) eu, were established. Small amounts of cis-stilbene were also formed. A kinetic analysis showed the reaction is first order in cluster and silane concentrations but zero order in alkyne concentration. The reaction is strongly inhibited by CO but is unaffected by mercury. A mechanism involving CO dissociation, silane oxidative addition, alkyne addition, a Si−C bond-forming step, and silylolefin dissociation is proposed with all transformations occurring at a ruthenium triangle. Pt3Ru6(CO)20(μ3-TolC2Tol)(μ3-H)(μ-H), 2b, was also found to be an effective catalyst for the hydrosilylation of TolC2Tol to (E)-Tol(H)C2(SiEt3)Tol, TOF of 32 h-1. Ru3(CO)9(μ3-PhC2Ph)(μ-H)2 and PtRu2(CO)8(μ3-PhC2Ph)(dppe) are relatively poor catalysts, TOF = 3.9 and 2.3 h-1, respectively. [NBu4][Pt3Ru6(CO)20(μ3-PhC2Ph)(μ-H)], 3, formed by deprotonation of 2a, also exhibits good catalytic activity, but its catalysis is inhibited by mercury, which may be indicative of heterogeneous catalysis.
Classical and novel discriminant features for affect recognition from speech (2005)

This paper investigates the performance and relevance of a set of acoustic features for the task of automatic recognition of affect from speech using machine learning techniques. Eighty seven novel and classical features related to loudness, intonation, and voice quality, are examined. Using feature selection, the results yield a performance level of 49.4% recognition rate (compared to a human performance rate of 60.4% and a chance level of 20%), while the relevance results show that the more exploratory and novel subset of these features outrank the more classical features in the recognition task. In the active research area of recognition of affect from speech it is of particular interest to obtain acoustic features that provide results closer to those of human recognition abilities. While many now “classic” features have been proposed in the literature, their performance has still fallen short of human recognition, suggesting the need to continue a search for novel features and methods. This paper briefly highlights results from an extensive investigation developing new features, and comparing them side-by-side with classical ones using machine learning techniques. (See [1] for many details omitted in this paper.) Algorithms and features associated with modeling loudness, intonation, and voice quality are highlighted in § 2, 3 and 4 respectively, and results of the experiments in §5 with some concluding remarks in § 6.
Engineering Computation: An Introduction Using MATLAB and Excel (2008)

The strength of Engineering Computation is its combination of the two most important computational programs in the engineering marketplace today, MATLAB® and Excel®. Engineering students will need to know how to use both programs to solve problems. 
While it is important to teach the mechanics of using the relevant tools, those tools can change so the focus of this text is on the fundamentals of engineering computing: algorithm development, selection of appropriate tools, documentation of solutions, and verification and interpretation of results.
Table of contents
PART 1: COMPUTATIONAL TOOLSChapter 1: Computing ToolsChapter 2: Excel FundamentalsChapter 3: MATLAB FundamentalsChapter 4: MATLAB ProgrammingChapter 5: Plotting DataPART 2: ENGINEERING APPLICATIONSChapter 6: Finding the Roots of EquationsChapter 7: Matrix MathematicsChapter 8: Solving Simultaneous Equations Chapter 9: Numerical IntegrationChapter 10: Optimization
Therapeutic Ultrasound: Physiological Role, Clinical Applications and Precautions (2017)

Background: Sound travels in waves that transport energy from one location to another. Ultrasound is the name given to sound waves that have frequencies greater than 20000Hz. It's too high pitched for human hearing, but many animals, such as dogs, cats and bats can hear ultrasound. As the ultrasound waves travel through tissues, they are partly transmitted to deeper structures, partly reflected back to the transducer as echoes, partly scattered, and partly transformed to heat. The amount of echo returned after hitting a tissue interface is determined by a tissue property called acoustic impedance which is an intrinsic physical property of a medium defined as the density of the medium times the velocity of ultrasound wave propagation in the medium. Physiologic effect of US: The thermal therapeutic ultrasound include increased tissue temperature, hyperdynamic tissue metabolism, increased local blood flow, increased extensibility of collagen fibers, and reduced viscosity of fluid elements in the tissue. The nonthermal mechanisms include ultrasonic cavitation, gas body activation and mechanical stress or frequency resonance nonthermal processes. Therapeutic effects of US: Therapeutic ultrasound is delivered in two modes; the continuous mode in which the delivery of ultrasound is non-stop throughout the treatment period and the pulsed mode in which the delivery of ultrasound is intermittently interrupted. Essential treatment parameters for therapeutic ultrasound include frequency, intensity, treatment mode, treatment time. Clinical applications: US in damaged muscle accelerates the repair process due to the decrease in the response and number of inflammatory cells and increases the proliferation and differentiation of muscle cell lines together with the formation of the connective tissue, improving mechanical resistance in the early stages. US is used also in chronic pain syndrome, tissue repair and wound healing and extra and intracorporeal shock wave lithotripsy. Cancer therapy: High-intensity focused ultrasound is a noninvasive therapy that makes entire coagulative necrosis of a tumor in deep tissue. HIFU ablation can destroy all proliferating tumor cells and their feeding blood vessels at the same time; this may break interdependent vicious cycle of tumor angiogenesis and tumor growth. Conclusion: Applications of ultrasound in medicine for therapeutic purposes have been an accepted and beneficial use of ultrasonic biological effects for many years. While therapeutic ultrasound is safe for treating many clinical conditions, it may cause substantial bioeffects and patients should be fully informed of possible benefits and risks.
A Laboratory Guide to Glycoconjugate Analysis (1995)

18. 2 Principle of FACE/Gel Retardation Assay . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 349 18. 3 Labelling of Oligosaccharides with ANTS . . . . . . . . . . . . . . . . . .
Osteoarthritis of the patella, lateral femoral condyle and posterior medial femoral condyle correlate with range of motion (2013)

For clinical relevance, soft tissue release and osteophyte resection around the patella, lateral femoral condyle and posterior medial femoral condyle might be indicated to obtain a higher degree of knee flexion angle.
Tsukushi is essential for the formation of the posterior semicircular canal that detects gait performance (2021)

Tsukushi is a small, leucine-rich repeat proteoglycan that interacts with and regulates essential cellular signaling cascades in the chick retina and murine subventricular zone, hippocampus, dermal hair follicles, and the cochlea. However, its function in the vestibules of the inner ear remains unknown. Here, we investigated the function of Tsukushi in the vestibules and found that Tsukushi deficiency in mice resulted in defects in posterior semicircular canal formation in the vestibules, but did not lead to vestibular hair cell loss. Furthermore, Tsukushi accumulated in the non-prosensory and prosensory regions during the embryonic and postnatal developmental stages. The downregulation of Tsukushi altered the expression of key genes driving vestibule differentiation in the non-prosensory regions. Our results indicate that Tsukushi interacts with Wnt2b, bone morphogenetic protein 4, fibroblast growth factor 10, and netrin 1, thereby controlling semicircular canal formation. Therefore, Tsukushi may be an essential component of the molecular pathways regulating vestibular development.
LOWER ST. JOHNS RIVER TOTAL MAXIMUM DAILY LOAD COMPLIANCE USING OPTIMIZATION ANALYSIS OF POINT AND NON-POINT SOURCE LOADS (2007)

LOWER ST. JOHNS RIVER TOTAL MAXIMUM DAILY LOAD COMPLIANCE USING OPTIMIZATION ANALYSIS OF POINT AND NON-POINT SOURCE LOADSSt. Johns River Water Management District (SJRWMD) has been participating and assisting affected parties in addressing water quality issues in the Lower St. Johns River (LSJR) basin. The ultimate goal is to improve the water quality throughout the District. One of many water quality improvement approaches has been the establishment of Total Maximum Daily Load (TMDL) limits for municipalities,...Author(s)Casey FitzgeraldPaul SteinbrecherMitch GriffinAvinash PatwardhanBill DunnSourceProceedings of the Water Environment FederationSubjectSession 52: TMDL: A Four Letter WordDocument typeConference PaperPublisherWater Environment FederationPrint publication date Jan, 2007ISSN1938-6478SICI1938-6478(20070101)2007:14L.3899;1-DOI10.2175/193864707787974058Volume / Issue2007 / 14Content sourceWEFTECFirst / last page(s)3899 - 3911Copyright2007Word count220
Inhibition of restriction endonuclease hydrolysis by phosphorothioate-containing DNA (1989)

Journal Article Inhibition of restriction endonuclease hydrolysis by phosphorothioate-containing DNA Get access Jon R. Sayers, Jon R. Sayers Max Planck Institut für Experimentelle MedizinAbteilung Chemie, Hermann-Rein Strasse 3, D-3400 Göttingen, FRG Search for other works by this author on: Oxford Academic PubMed Google Scholar David B. Olsen, David B. Olsen Max Planck Institut für Experimentelle MedizinAbteilung Chemie, Hermann-Rein Strasse 3, D-3400 Göttingen, FRG Search for other works by this author on: Oxford Academic PubMed Google Scholar Fritz Eckstein Fritz Eckstein Max Planck Institut für Experimentelle MedizinAbteilung Chemie, Hermann-Rein Strasse 3, D-3400 Göttingen, FRG Search for other works by this author on: Oxford Academic PubMed Google Scholar Nucleic Acids Research, Volume 17, Issue 22, 25 November 1989, Page 9495, https://doi.org/10.1093/nar/17.22.9495 Published: 25 November 1989 Article history Accepted: 06 October 1989 Published: 25 November 1989
ChemInform Abstract: Hydrolysis of Methylthiazolopyridines. X‐Ray Crystal Structure of 3‐Acetamido‐2(1H)‐pyridinethione. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Rotorcraft Dynamic Platform Landings Using Robotic Landing Gear (2021)

Abstract Articulating landing gear that use closed-loop feedback control are proven to expand the landing capabilities of rotorcraft on sloped and rough terrain. These systems are commonly referred to as robotic landing gear (RLG). Modern RLG systems have limitations for landing on dynamic platforms because their controllers do not incorporate fuselage roll and roll rate feedback. This work presents a proven crashworthy cable-driven RLG system for the commercial S-100 Camcopter that expands static landing zone limits by a factor of three and enables dynamic platform landings in rough sea state (SS) conditions. A new roll and foot-force feedback fused control algorithm is developed to enable ship deck landings of an RLG equipped S-100 without the need for deck lock or advanced vision-based landing systems. Multibody dynamic simulations of the aircraft, landing gear, and new control system show the benefits of this combined roll and force feedback approach. Results include experimental dynamic landings on platforms rolling under sinusoidal motion and simulated SS conditions. The experiments demonstrate, in a limited fashion, the usability of the RLG through ground experimentation, and the results are compared to simulations. Additional simulations of landings of the S-100 with rigid and active landing gear with more challenging landing conditions than experimentally tested are presented. Such results aid in understanding how RLG with this new roll and contact force fused controller prevent dynamic rollover.
Caulerpa lentilliferapolysaccharides enhance the immunostimulatory activity in immunosuppressed mice in correlation with modulating gut microbiota (2019)

In this study, the immunostimulatory activity of Caulerpa lentillifera polysaccharides (CLP) was elucidated in cytoxan (CTX)-induced immunosuppressed BALB/c mice. The results showed that CLP ameliorated the CTX-evoked damage to body weight, colon length and thymus/spleen indexes and enhanced the secretions of interleukin (IL)-1β, tumor necrosis factor (TNF)-α and superoxidase dismutase (SOD) in serum and thymic, splenic and colonic tissues of the immunosuppressed mice. Besides, CLP promoted the production of secretory immunoglobulin A (SIgA) and mucin2 in the colonic tissue of the immunosuppressed mice. Associated with the above immunostimulatory effects, CLP positively affected the production of short chain fatty acids (SCFAs) and microbiota diversity and composition, such as improvement in the growth of Lactobacillus, Coriobacteriaceae, Ruminococcaceae, Clostridium_XVIII and Helicobacter, whereas it suppressed the microbial populations of Bacteroides, Barnesiella and Lachnospiraceae. These findings suggested that CLP modulated SCFA production and gut microbiota in the immunosuppressed mice, evoking the colonic mucosal immunity, which might activate the systemic immunity in blood, thymus and spleen. The results could be helpful for understanding the functions of CLP, supporting their potential as novel prebiotics and immunostimulators.
Polymorphic haplotypes of CRELD1 differentially predispose Down syndrome and euploids individuals to atrioventricular septal defect (2012)

To explore the role of CRELD1 variants on congenital heart defects, we sequenced the entire reading frame of CRELD1 in the samples from Kolkata and adjoining areas. Nearly, 400 participants were included in the genetic association study and they were stratified as Down syndrome (DS) with atrioventricular septal defect (AVSD), DS without AVSD, euploid with AVSD, and euploid without AVSD. A significant association was found between AVSD and three polymorphisms, namely rs9878047 (c.1049-129T > C), rs3774207 (c.1119C > T), and rs73118372 (c.1136T > C) among the Down syndrome and euploid individuals. The polymorphism rs73118372, involves a transition (c.1136T > C) that leads to change in amino acid methionine to threonine which alters protein secondary structure as confirmed by the bioinformatics software SOPMA. In addition, two haplotypes, C-T-C and C-T-T, in the order of loci rs9878047-rs3774207-rs73118372 were associated with incidence of AVSD among euploid and Down syndrome, with a slightly higher odds ratio in the later group. We hypothesize that these haplotypes increase the risk of AVSD, and the susceptibility is exacerbated in DS, possibly due to the trisomy 21 genetic background. Moreover, we report for the first time on an interaction between the mutant alleles of rs3774207 and rs73118372 which could disrupt the delicate balance between different CRELD1 isoforms.