gebhart/patrepeval huggingface dataset:
MODELLING CHANGES IN EYE FIXATION PATTERNS WHILE DRIVING (1998)

It is possible that eye fixations reflect the processing state of the driver and may provide some insight into the driver's cognitive model of the situation. The goal of this project is to characterise how eye fixation patterns change as the driving situation changes. Eye movements are recorded while driving in a simulator under controlled visual and road conditions. In the first task (driving on an open road), the eye movements are modelled with Markov matrices and identify two scanning patterns. In the second task (following a lead car) a new Markov matrix is derived in which a new pattern of movement has been added to the existing two patterns. The results support the idea that Markov models of eye movement behaviour in simple situations can be linearly combined to predict behaviour in complex tasks. For the covering abstract see IRRD E102207.
Microfluidique et diffusion de rayons X aux petits angles : des outils pour étudier les processus sol-gel (2007)

Click to increase image sizeClick to decrease image sizeX-ray scattering is a classical tool to probe soft matter from the atomic scale (1 Å) to the colloidal one (100 nm). However, papers relating SAXS measurements combined with microfluidics are scarce. This works describes the microfabrication of thin microfluidic devices in polyimide (Kapton) and the fabrication of a simple polyimide-based millifluidic system. These systems are well-suited to perform X-ray scattering measurements using intensed microfocussed beams, as Kapton is both relatively resistant to the high intensities generated by a synchrotron, and almost transparent to X-rays. We show networks of microchannels obtained using laser ablation and fusion bonding between two Kapton films. We also present a simple way to fabricate a polyimide-based steady droplet-generating system. The possibilities offered using such devices are illustrated with X-ray scattering experiments. First, an investigation of a complex fluid undergoing a shear-induced transition in a microchannel was successfully performed. Then, structural and composition data were reached by coupling SAXS measurements and flowing droplets within a polyimide millifluidic capillary. These experiments demonstrate that structural measurements in the 1 Å-20 nm range can be obtained with a spatial resolution of a few microns.
High-pressure carbon dioxide uptake for porous organic cages: comparison of spectroscopic and manometric measurement techniques (2013)

A chemoselective spectroscopic method for measuring CO2 sorption isotherms at pressures up to 14 MPa (140 bar) is validated against manometric measurements and molecular simulations, giving insights into the preferred sorption sites in various crystalline porous organic cages.
Enhanced Antimicrobial Effects of Decellularized Extracellular Matrix (CorMatrix) with Added Vancomycin and Gentamicin for Device Implant Protection (2017)

The hydration of the CanGaroo ECM with an antibiotic solution prevented Staphylococcus species growth in vitro and substantially reduced the incidence of CIED pocket infections in an in vivo rabbit model.
ABA activation of an MBP kinase in Pisum sativum epidermal peels correlates with stomatal responses to ABA (2000)

In-gel protein kinase assays using myelin basic protein (MBP) as substrate have been used to demonstrate that abscisic acid (ABA) activates an MBP kinase (AMBP kinase) in epidermal peels prepared from leaves of the Argenteum mutant of pea, Pisum sativum L. AMBP kinase has the characteristics of a mitogen-activated protein kinase (MAPK): it utilizes MBP preferentially as an artificial substrate, it is rapidly and transiently activated, it is of the appropriate size (molecular weight c. 45 kDa), requires tyrosine phosphorylation for activity and is tyrosine phosphorylated upon activation. Reverse transcription-PCR was used to generate a previously-cloned MAPK from guard cells, epidermis and mesophyll and immunoblotting using an antibody raised against a mammalian MAPK detected MAPK-related proteins, including one of 45 kDa, in epidermal peels, mesophyll and guard cells. Inhibition of AMBP kinase activation by PD98059, a specific inhibitor of MAPK kinase, and thus MAPK activation, correlated with PD98059-inhibition of ABA-induced stomatal closure and dehydrin gene expression, suggesting that ABA effects in pea epidermal peels require MAPK activation. AMBP kinase was not activated by ABA in guard cells isolated by enzyme treatment. However, a protein kinase of c. 43 kDa was activated by ABA in isolated guard cells, but not in mesophyll or epidermal tissue.
ChemInform Abstract: DIAZO COMPOUNDS AND AZIDES. LII. STABLE AZOMETHINE IMINE DIPOLES FROM DIAZO COMPOUNDS AND 3H‐1,2,4‐TRIAZOLE‐3,5(4H)‐DIONES (1985)

Abstract Eine Reihe von arylsubstituierten Diazoverbindungen wie z.B. (I) reagieren mit dem Triazoldion (IIa) [und analog auch mit (IIb) bzw. (IIc)] zu den Titeldipolen (III).
Complex articulated object tracking (2005)

In this paper new results are presented for tracking complex multi-body objects. The theoretical framework is based on robotics techniques and uses an a-priori model of the object including a general mechanical link description. A new kinematic-set formulation takes into account that articulated degrees of freedom are directly observable from the camera and therefore their estimation does not need to pass via a kinematic-chain back to the root. By doing this the tracking techniques are efficient and precise leading to real-time performance and accurate measurements. The system is locally based upon an accurate modeling of a distance criteria. A general method is given for defining any type of mechanical link and experimental results show prismatic, rotational and helical type links. A statistical M-estimation technique is applied to improve robustness. A monocular camera system was used as a real-time sensor to verify the theory.
The Global Influence of Sodium on Cyanobacteria in Resuscitation from Nitrogen Starvation (2023)

Dormancy and resuscitation are key to bacterial survival under fluctuating environmental conditions. In the absence of combined nitrogen sources, the non-diazotrophic model cyanobacterium <i>Synechocystis</i> sp. PCC 6803 enters into a metabolically quiescent state during a process termed chlorosis. This state enables the cells to survive until nitrogen sources reappear, whereupon the cells resuscitate in a process that follows a highly orchestrated program. This coincides with a metabolic switch into a heterotrophic-like mode where glycogen catabolism provides the cells with reductant and carbon skeletons for the anabolic reactions that serve to re-establish a photosynthetically active cell. Here we show that the entire resuscitation process requires the presence of sodium, a ubiquitous cation that has a broad impact on bacterial physiology. The requirement for sodium in resuscitating cells persists even at elevated CO<sub>2</sub> levels, a condition that, by contrast, relieves the requirement for sodium ions in vegetative cells. Using a multi-pronged approach, including the first metabolome analysis of <i>Synechocystis</i> cells resuscitating from chlorosis, we reveal the involvement of sodium at multiple levels. Not only does sodium play a role in the bioenergetics of chlorotic cells, as previously shown, but it is also involved in nitrogen compound assimilation, pH regulation, and synthesis of key metabolites.
The Vibrational Fine Structure of the 1T1g←1A1g Absorption Band of [Co(NH3′)6]3+ (1980)

Abstract The crystal absorption spectra of [Co(NH3)6][Ir(CN)6] and [Co(ND3)6][Ir(CN)6] were studied at 4.2 K. The vibrational fine structure observed on the 1T1g←1A1g absorption band of the hexaamminecobalt(III) complexes was interpreted in terms of a vibronic intensity scheme in comparison with the vibrational frequencies of the complexes. The deuteration shifts helped to confirm the assignments of the structure. It was found that, as well as the skeletal vibrations of the CoN6 group, the NH3 (and ND3) rocking and the H–N–H symmetric deformation modes are effective in the vibronic intensity mechanism of the bands.
Reconstruction and analysis of Twitter conversation graphs (2012)

User interactions over social networks has been an emergent theme over the last several years. In contrast to previous work we focus on characterizing user communications patterns around an initial post, or conversation root. Specifically, we focus on how other users respond to these roots and how the complete conversation initiated by this root evolves over time. For this purpose we focus our investigation on Twitter, the biggest micro-blogging social network. To the best of our knowledge this is the first such method that is able to reconstruct complete conversations around initial tweets. We propose a robust approach for reconstructing complete conversations and compare the resulting graph structures against those obtained from previous crawling strategies based on keyword searches. Our crawl provides a large scale dataset, ideal for computer scientists to run large scale experimental evaluations, however our dataset is made of a collection of small scale, highly controlled and complete conversation graphs ideal for a sociological investigation. We believe our work will provide the proper dataset to establish concrete collaborations with interdisciplinary expertise.
Assessment of sperm nuclear quality after in vitro maturation of fresh or frozen/thawed mouse pre-pubertal testes (2017)

This work was supported by Rouen University Hospital, Ligue contre le Cancer, Agence de la Biomédecine, Association Laurette Fugain, France Lymphome Espoir, and co-supported by European Union and Région Normandie. Europe gets involved in Normandie with European Régional Development Fund (ERDF). The authors declare that they have no conflict of interest.
Effects of transcranial direct current stimulation (tDCS) on sensory evoked potentials (2010)

We present a combined experimental/computational modeling approach aimed at studying the effects of transcranial Direct Current Stimulation (tDCS) on neuronal systems. More particularly, we introduce i) a neural mass model (neuronal population level) of the cerebral cortex and ii) a coupling model between the considered neuronal population and an externally-applied electric field. We then use this computational modeling approach to interpret evoked potentials (EPs) recorded from the somatosensory cortex of the rabbit under tDCS. Results showed that the model could accurately reproduce the time-course of actual EPs (polarity and latency of main peaks) recorded under control (i.e. “no tDCS stimulation”) condition. From real data, we also identified the “major” effects of tDCS on EPs in terms of shape modifications and we studied the necessary and sufficient conditions for which the model could reproduce these effects. We found that pyramidal cells should be depolarized (resp. hyperpolarized) in order to simulate the effects of anodal (resp. cathodal) currents. We also found that some interneurons are sensitive to externally-applied fields, indicating that modelling efforts need to also consider the role of these neurons to fully understand interactions between stimulation currents and underlying neuronal systems.
Novel Bioinformatics Method for Identification of Genome-Wide Non-Canonical Spliced Regions Using RNA-Seq Data (2014)

We conclude that our RSW pipeline is a practical approach for identifying non-canonical splice junction sites on a genome-wide level. We demonstrate that our pipeline can detect novel splice sites in RNA-Seq data generated under similar conditions for multiple species, in our case mouse and human.
CH bond activation and radical–surface reactions for propylene and methane over α-Bi2O3 (1987)

A molecular-orbital study has been made of CH activation in methane and the methyl group of propylene by an α-Bi2O3 surface. Three oxidation states of the surface bismuth cations were modelled: II(reduced), III(normal) and V(oxidized). It was found that barriers to the formation of surface OH– and gas-phase methyl and allyl radicals decrease as the bismuth oxidation state increases. This is because the radical electron from hydrogen is promoted by σ-bond formation to successively lower-energy bismuth 6s, 6p lone-pair or surface-state dangling bond orbitals as the state of bismuth oxidation increases. Experimental results in the literature also show this trend for forming gas-phase allyl radicals: in an oxidizing environment with O2 in the gas stream the barrier is lower than in a reducing environment with no oxygen. We found a similar trend for stabilities of heterolytically adsorbed dissociation products and for homolytic adsorption on oxygen. The increased stability with increasing bismuth oxidation state is the result of reducing lower-lying surface orbitals. We found heterolytic adsorption, H on O2– and CH3 or C3H5 on Bi, most stable for the BiIII and BiV surfaces and we predict that the BiII surface is unreactive.
Managing P2P services via the IMS (2007)

The key aim of our work was to illustrate the benefits and means to deploy P2P services via the IMS. Having demonstrated the technical viability of P2P-IMS we have also found a way to add a new management dimension to existing P2P systems. P2P-IMS comes with a natural "data management" mechanism, addressing the DRM problem which is still a major hurdle in existing P2P platforms. In P2P-IMS, the IMS manages user registration, authentication, and authorisation, as well as monitoring, charging and billing. The immediate benefit is that P2P-IMS can be used as a building block to deploy managed secure group communication services. By contrast to existing P2P systems, in P2P-IMS group members are authenticated securely. In this way it is possible to manage authorisation policies in P2P communication and data exchange.
The Microscopic Physical Cause for the Density Maximum of Liquid Water (2013)

The existence of a density maximum at 277 K is probably the most prominent anomaly among the many very special thermodynamic properties of liquid water. While usually attributed to so-called hydrogen bonding, the microscopic physical cause of this prominent anomaly is still elusive. Here we show that the density anomaly is caused by those short-range electrostatic forces, which are generated by the quadrupole and higher moments of the charge distributions present in liquid-phase water molecules. This conclusion derives from 20 ns replica exchange molecular-dynamics simulations with closely related polarizable four-, five-, and six-point water models. As soon as the model complexity suffices to represent the higher electrostatic moments with sufficient accuracy, the density temperature profile n(T) calculated for T ∈ [250,320] K at the standard pressure 1 bar locks in to the experimental observation. The corresponding six-point model is, therefore, the most simple available cartoon for liquid-phase water molecules.
Highly Efficient Dehydrogenation of 5‐Benzyl‐3‐phenyl‐2‐thioxoimidazolidin‐4‐one: Microwave versus Flash Vacuum Pyrolysis Conditions (2012)

Abstract 5‐Benzyl‐3‐phenyl‐2‐thioxoimidazolidin‐4‐one underwent thermal dehydrogenation to afford 5‐benzylidene‐2‐thioxoimidaxolidin‐4‐one under microwave and flash vacuum pyrolysis conditions. A high predominance of the Z ‐isomer over the E ‐isomer of the imidazolidinone product was achieved. By using DFT and NBO calculations, the mechanism of the dehydrogenation and the selectivity were also explored.
Color Doppler sonography for evaluating response to transcatheter arterial embolization and percutaneous ethanol injection therapy and for detecting recurrence of hepatocellular carcinoma. (2000)

Eighty-six patients (mean age, 63 years) with 92 hepatocellular carcinomas (2.0 cm or greater in diameter; mean +/- SD, 3.5 +/- 1.6 cm) underwent color Doppler sonography before and after transcatheter arterial embolization and after subsequent percutaneous ethanol injection for (1) identification of pulsatile flow in the residual tumor area after transcatheter arterial embolization, (2) evaluation of therapeutic effectiveness of combined transcatheter arterial embolization and percutaneous ethanol injection, and (3) detection of recurrence during follow-up evaluation. Before and 2 weeks after transcatheter arterial embolization, color Doppler sonography revealed pulsatile flow in 76 (82.6%) and 43 (46.7%)lesions, respectively. After percutaneous ethanol injection, tumor stains in these lesions completely disappeared on digital subtraction angiography (gold standard). During follow-up study (3 to 45 months), digital subtraction angiography revealed recurrence in 73 patients (38 local recurrences and 19 new lesions [2.0 cm or greater]), whereas color Doppler sonography revealed pulsatile flow in 76.3% (local) and 63.2% (new) (not significant). Color Doppler sonography was useful for complying with our three objectives, especially for detecting local recurrence during follow-up evaluation.
Validity of HAT Score for Predicting Symptomatic Intracranial Hemorrhage in Acute Stroke Patients with Proximal Occlusions: Data from Randomized Trials of Sonothrombolysis (2011)

The HAT score has reasonable external validity for predicting the risk of sICH following intravenous thrombolysis in patients with PAO. Moreover, higher HAT scores appear to be associated with higher likelihood of persisting occlusion in tPA-treated patients.
Query Optimization Properties of Modified VBS (2019)

Valuation-Based~System can represent knowledge in different domains including probability theory, Dempster-Shafer theory and possibility theory. More recent studies show that the framework of VBS is also appropriate for representing and solving Bayesian decision problems and optimization problems. In this paper after introducing the valuation based system (VBS) framework, we present Markov-like properties of VBS and a method for resolving queries to VBS.
The potent and lung-selective inhaled pan JAK inhibitor TD-8236 limits airway inflammation without affecting systemic immunity in mice (2019)

Janus kinase (JAK) inhibitors target a family of kinases that transduce cytokine mediated signals via the JAK / Signal Transducer and Activator of Transcription (STAT) pathway. JAK/STAT signaling cytokines contribute to asthma airway inflammation. TD-8236 is a potent, lung-selective pan-JAK inhibitor designed for inhaled delivery in an effort to achieve maximal activity at the site of lung inflammation while minimizing the adverse effects of systemic JAK inhibition. The aim of this study was to demonstrate <i>in vivo</i> target engagement and lung selectivity of TD-8236 in mice. TD-8236 (0.5 mg/mL) dosed to the lung via oral aspiration (OA) demonstrated statistically significant inhibition of IL-13-induced pSTAT6 in the lungs of mice. One dose of TD-8236 (1 mg/mL, OA) yielded statistically significant pSTAT6 inhibition over pretreatment times ranging from 1 to 24 hrs (max = 94%). PK-PD analysis revealed a linear relationship between unbound TD-8236 lung exposure and inhibitory response (EC50 = 74 nM). Aerosolized TD-8236 (1 mg/mL) also inhibited IL-13-induced pSTAT6 by 63% in the lungs of mice. In a mouse model of airway inflammation, TD-8236 (OA) dosed for 7 days produced inhibition of <i>Alternaria alternata</i>-induced lung eosinophilia (ED50 = 0.03 mg/kg). In contrast, spleen NK cell numbers were not reduced in mice after 7 days of dosing TD-8236 (OA). These data suggest that TD-8236, when delivered locally to the mouse lung, provides anti-inflammatory activity without measurable systemic immunosuppression. The importance of JAK/STAT cytokines in asthma warrants further investigation of TD-8236 as a novel inhaled non-steroidal therapy for this disease.
The Expression of Homocysteine (HCY) C-Reaction Protein (CRP) in Patients with Chronic Heart Failure (2010)

Objective:To evaluate the concentration of serum homocysteine,C-reactive protein in patients with chronic heart failure (CHF).Methods:Our study included 60 patients with chronic heart failure(CHF)(CHF group)and 50 healthy subjects after examination served as healthy control group.CHF group were divided into three subgroups according to NYHA cardiac function classification(abbreviated as heart function Ⅱ,Ⅲ,Ⅳ groups).The levels of homocysteine(HCY)、C-reaction protein(CRP)were measured.Left wmtricular end diastolic diameter(LVEDD)and left ventricular ejection fraction(LVEF)of all patients were determinated by echocardiogram when they were in hospital.Results:①Plasma concentrations of HCY and CRP in CHF group were significantly higher than those in control group before treatment(P0.05);②Before the treatment the conclusion in different CHF group is that:individuals with higher level of HCY and CRP concentration had higher NYHA cadica function classification (P0.05);③After the treatment level of HCY and CRP in CHF group were significantly lower than those before be treated(P0.05);④Correlation analysis indicated that HCY and CRP level were positively correlated with LVEDD,however,were negatively correlate with LVEF(P0.05).Conclusions:①The level of HCY and CRP in CHF group is positive correlated with NYHA cardiac function classification and LVEDD.The level of plasma HCY and CRP elevated in these patients with the increase of NYHA cardiac function classification and lower of LVEDD.They may reflect the cardiac function classification clearly.②The level of plasma HCY and CRP will become lower when patient with better cardiac function classification.They may reflect the effection of treat in CHF patients.
Luminescence and Photoconductivity in Silver Chloride with Laser Excitation (1966)

Abstract In zone refined AgCl, luminescence can be excited by ruby laser light through two‐photon processes, while the photoconductivity is a result of ionization of donors. The luminescence spectrum shows some phonon structure not observed with steady uv excitation.