gebhart/patrepeval huggingface dataset:
Mitogenic and receptor activities of human growth hormone 108ndash;129 (1995)

Mitogenic and receptor activities of human growth hormone 108-129.Journal of Biological ChemistryVol. 268Issue 30PreviewWe have selectively synthesized a number of peptides encompassing the region of helix 3 of growth hormone (GH). These peptides and native human (h) GH have been evaluated for mitogenic and receptor activities in 3T3-F442A preadipocytes. In this system, wild type hGH is anti-mitogenic. In contrast, hGH 108-129 stimulated DNA synthesis while other GH-derived peptides were ineffective. hGH (L) 108-129 had an EC50 of about 0.2 nM and was maximally effective at about 0.5 nM in stimulating [3H]thymidine incorporation in 3T3-F442A cells. Full-Text PDF Open Access Vol. 268, p. 22520 Page 22521 Table 1: Two substance entries have been misaligned. The correct table is printed below.Tabled 1 Open table in a new tab Fig. 1: The stimulatory effect of hGH [L] 108-129 on [3H] thymidine incorporation in 3T3F442A cells could not be replicated and this peptide cannot be considered to have this activity.
Voltammetric Determination of Urinary 1‐Hydroxypyrene Using Molecularly Imprinted Polymer‐Modified Screen‐Printed Carbon Electrodes (2004)

Abstract A two step non‐competitive affinity method for the trace determination of 1‐hydroxypyrene (1‐OHP) using a disposable molecularly imprinted polymer (MIP) modified screen‐printed carbon electrode (MIP‐SPCE) has been developed. The MIP was synthesized according to a novel strategy, which is described, and is capable of rebinding the phenolic analyte, 1‐hydroxypyrene (1‐OHP), from high pH aqueous organic media, via ionic interactions. In the first step of our method 1‐OHP was accumulated at the MIP‐SPCE from 35% aqueous methanol containing 0.014 M NaOH and 0.14 M NaCl, at open circuit. In the second step, the resulting SPCE with accumulated 1‐OHP was then transferred to fresh, clean phosphate buffered aqueous methanol, and subjected to cyclic voltammetry (CV) or differential pulse voltammetry (DPV). The latter technique proved to be more sensitive at detecting 1‐OHP, with a limit of detection of 182 nM and a linear range to 125 μM on unmodified electrodes. The possible effects of interference by related phenolic compounds in the MIP‐SPCE of 1‐OHP were investigated. Finally the method was evaluated by carrying out 1‐OHP determinations on spiked human urine samples; the recovery of 1‐OHP was 79.4% and the coefficient of variation was found to be 7.7% ( n= 4) using a separate MIP‐SPCE for each determination. Therefore, the performance data suggests that the method is reliable at the concentrations examined in this study. The method was found to be superior to the direct determination of 1‐OHP in human urine by DPV alone, which was greatly affected by interference from uric acid.
FLAG Simulations of the Elasticity Test Problem of Gavrilyuk et al. (2014)

This report contains a description of the impact problem used to compare hypoelastic and hyperelastic material models, as described by Gavrilyuk, Favrie & Saurel. That description is used to set up hypoelastic simulations in the FLAG hydrocode.
Handbook of sputter deposition technology (1992)

This book comprehensive overview of sputter deposition technology, a key technology mar materials research in the next decade. Cathodic sputtering is widely used in the microelectronics industry for silicon integrated circuit production, and for metallurgical coatings. High temperature superconductors can be synthesized with sputtering under nonequilibrium thermal conditions. Diamond films and ferroelectric materials are other applications.
On the fraction of sand grains bounded in molding materials – a new measurement technique (2010)

We present a method that allows to determine the fraction of unbounded sand grains in a compacted sand-binder system as used in foundry practice. The method uses a dynamic gas permeability measurement technique, which reveals that in foundry sands the permeability is not a constant but depends on the pressure difference driving the flow through it. This effect can be understood on the basis of so-called rattlers, being unbounded sand grains. A model of the effect is developed and evaluated with respect to the volume fraction of unbounded sand grains. The amount of unbounded grains is typically between 1 and 10 volume percent.
Spectral Methods Based on Prolate Spheroidal Wave Functions for Hyperbolic PDEs (2005)

We examine the merits of using prolate spheroidal wave functions (PSWFs) as basis functions when solving hyperbolic PDEs using pseudospectral methods. The relevant approximation theory is reviewed and some new approximation results in Sobolev spaces are established. An optimal choice of the band-limit parameter for PSWFs is derived for single-mode functions. Our conclusion is that one might gain from using the PSWFs over the traditional Chebyshev or Legendre methods in terms of accuracy and efficiency for marginally resolved broadband solutions.
A uniform method for analytically modeling mulit-target acquisition with independent networked imaging sensors (2014)

The problem solved in this paper is easily stated: for a scenario with 𝑛 networked and moving imaging sensors, 𝑚 moving targets and 𝑘 independent observers searching imagery produced by the 𝑛 moving sensors, analytically model system target acquisition probability for each target as a function of time. Information input into the model is the time dependence of 𝘗<sub>∞</sub> and 𝜏, two parameters that describe observer-sensor-atmosphere-range-target properties of the target acquisition system for the case where neither the sensor nor target is moving. The parameter 𝘗<sub>∞</sub> can be calculated by the NV-IPM model and 𝜏 is estimated empirically from 𝘗<sub>∞</sub>. In this model 𝑛, 𝑚 and 𝑘 are integers and 𝑘 can be less than, equal to or greater than 𝑛. Increasing 𝑛 and 𝑘 results in a substantial increase in target acquisition probabilities. Because the sensors are networked, a target is said to be detected the moment the first of the 𝑘 observers declares the target. The model applies to time-limited or time-unlimited search, and applies to any imaging sensors operating in any wavelength band provided each sensor can be described by 𝘗<sub>∞</sub> and 𝜏 parameters.
Bi-directional fast flow sensor with a large dynamic range (1999)

In this article an extended mass-flow sensor is presented. Apart from the magnitude of the flow, as an add-on to the traditional anemometer, this sensor also measures the direction of the flow. This is of interest for the flow sensor market in general, and more in particular for the safety monitoring of low over-pressure systems like surgeries and cleanrooms where the risk of reverse flow needs to be avoided at all times. It detects the smallest amount of gas-flow, down to approximately 100 m s -1 airflow up to high flow levels of 1 m s -1 . The response time is of the order of milliseconds.
ChemInform Abstract: Aminoazole Imines. Part 2. Synthesis and Characterisation of Some 2‐Amino‐thiazole, ‐benzothiazole, ‐benzoxazole and 3‐Amino‐1,2,4‐triazole Imines. (1986)

Abstract Man erhält die Azolimine (III) durch Kondensation der Aminoazole (I) mit den Benzaldehyden (II).
ChemInform Abstract: Synthesis of Substituted Pyridines and Pyridazines via Ring Closing Metathesis. (2009)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Crystal Structure of Tetrameric Cobalt(II) Acetylacetonate (1965)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCrystal Structure of Tetrameric Cobalt(II) AcetylacetonateF. A. Cotton and R. C. ElderCite this: Inorg. Chem. 1965, 4, 8, 1145–1151Publication Date (Print):August 1, 1965Publication History Published online1 May 2002Published inissue 1 August 1965https://pubs.acs.org/doi/10.1021/ic50030a012https://doi.org/10.1021/ic50030a012research-articleACS PublicationsRequest reuse permissionsArticle Views1165Altmetric-Citations118LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
In situ localization of amylase mRNA and protein. An investigation of amylase gene activity in normal human parotid gland. (1987)

The distribution of human salivary amylase mRNA was studied by in situ hybridization to a [32P]-labeled amylase cDNA probe. Amylase mRNA was localized to the apical portion of acinar cells in frozen sections of human parotid salivary gland. No hybridization was noted in ductal cells, skeletal muscle, or in connective tissue. These results were consistent with immunohistochemical localization of amylase. The technique of in situ hybridization was modified to permit localization of amylase mRNA in variously fixed, paraffin-embedded parotid glands. Although the hybridization signal decreased with all fixatives, the pattern of localization paralleled that obtained with frozen sections. No advantage was noted in fixation with ethanol-acetic acid or Bouin solution over routine fixation with formalin. These results have important implications for researchers interested in studies of gene expression. We have demonstrated that routinely fixed paraffin blocks of human tissue can be used for cellular localization of specific mRNA. In coordination with immunocytochemistry, in situ hybridization offers a powerful tool for studies of mRNA and protein expression in individual cells.
Lightweight Directory Access Protocol (v3): Technical Specification (2002)

This document specifies the set of RFCs comprising the Lightweight Directory Access Protocol Version 3 (LDAPv3), and addresses the IESG Note attached to RFCs 2251 through 2256.
Three-dimensional display in nuclear medicine (1989)

Several surface and volume rendering techniques are compared using nuclear medicine data including several new methods developed by the authors specifically for scintigraphic data. The techniques examined are summed projection, thresholded projection, threshold-based surface illumination, volumetric compositing, maximum-activity projection, sun-weighted maximum-activity projection, and variable attenuation. The advantages and disadvantages of each method are discussed in relation to the goals of three-dimensional display, which are defined herein. Selected images are shown to illustrate the usefulness of the methods.
Elimination of self-absorption in fluorescence hard-x-ray absorption spectra (1999)

Fluorescence detection is a convenient way to measure x-ray absorption spectra in situations where samples cannot be made in the required configuration. However, self-absorption effects cause considerable distortion of spectra measured in fluorescence. We describe a straightforward procedure to correct for such distortion in the hard-x-ray region using the known energy dependence of the x-ray absorption coefficients. This procedure is used to obtain the vanadium K-edge spectrum of single crystal ${\mathrm{V}}_{2}{\mathrm{O}}_{3}$ and we demonstrate that self-absorption is properly corrected. This facilitates the use of fluorescence detection even in the hard-x-ray region.
Supplementary Table and Figure Legends from A Comparative Genomic Approach for Identifying Synthetic Lethal Interactions in Human Cancer (2023)

&lt;p&gt;PDF file, 59K.&lt;/p&gt;
Fatigue Crack Initiation Simulation in Pure Iron Polycrystalline Aggregate (2016)

A numerical study was conducted to evaluate the fatigue crack initiation stage in pure α-iron. A two-dimensional synthetic polycrystalline aggregate was generated with Voronoi tessellation to represent the microstructure. Low-cycle fatigue experiments under fully reversed strain-controlled loading were conducted for different strain amplitudes. The stable stress-strain hysteresis loops were used to calibrate a non-linear kinematic hardening model for metal plasticity suitable for cyclic simulations. An existing procedure based on the Tanaka-Mura model for fatigue crack initiation was extended to body-centered cubic lattice to account for two orthogonal slip systems as potential crack locations. This procedure was applied for fully reversed fatigue simulations with various stress amplitudes ranging from low-cycle to high-cycle fatigue regime. The effect of the stress level on the crack morphology and the fatigue crack initiation life was evaluated. Finally the applicability and limitations of the proposed procedure was discussed.
Screening Non-Pd Metal Alloys and Crystalline Porous Materials used in Gas Separation Membranes (2015)

International audience
Antioxidant and anti-mutagenic effects of ebselen in yeast and in cultured mammalian V79 cells (2008)

Ebselen has a wide spectrum of interesting therapeutic actions including antioxidant, cytoprotective, neuroprotective and anti-inflammatory activities. Since its antioxidant effect is very well known, this paper links the effects of ebselen in redox cellular status to its possible involvement in the maintenance of the integrity of genomic information by using Saccharomyces cerevisiae strains proficient and deficient in antioxidant defences and the mammalian V79 cell line. Using the alkaline comet assay, we showed that 5-10 microM ebselen does not induce DNA damage in V79 cells. Similarly, these same concentrations diminished the extent of the DNA damage induced by hydrogen peroxide (H(2)O(2)). The modified comet assay using DNA glycosylases (formamidopyrimidine-DNA glycosylase and endonuclease II) showed that after pre-treatment with ebselen followed by exposure to H(2)O(2), oxidative damage as recognized by these enzymes was significantly lower. In the same way, ebselen showed strong activity against H(2)O(2)-induced oxidative damage in the anti-mutagenic assay using S. cerevisiae N123 strain and in the antioxidative assay by using S. cerevisiae strains lacking antioxidant defences. This antioxidant effect was more pronounced for the gpx3 delta mutant, which indicated that ebselen acts by mimicking the GPx3 catalytic activity. The results confirm that ebselen is involved in antioxidant defence and that its antioxidant ability contributes to its anti-mutagenic and anti-genotoxic action.
Dual Function Thin Slab Ultrafast Amplifier Producing 240W over a Range of Pulse Repetition Frequencies (2019)

Applications for ultrashort pulse (<; 100ps) laser systems are developing at an increasing rate. Broadly, the applications can be categorized as (a) low pulse repetition frequency (PRF) <; 1MHz, athermal machining with moderate pulse energies, and (b) high PRF, >1MHz highly localized (and controlled) melting with lower pulse energies. Ideally, a single technology platform should address the entire range of applications whilst providing the necessary average power to achieve productivity targets.
On the Impact of Quantization on Binaural MVDR Beamforming (2016)

Multi-microphone noise reduction algorithms in binaural hearing aids which cooperate through a wireless link have the potential to become of great importance in future hearing aid systems. However, limited transmission capacity of such devices necessitates the data compression of signals transmitted from one hearing aid to the contralateral one. In this paper we study the impact of quantization as a data compression scheme on the performance of the multi-microphone noise reduction algorithms. Using the binaural minimum variance distortionless response (BMVDR) beamformer as an illustration, we propose a quantization aware beamforming scheme which uses a modified cross power spectral density (CPSD) of the system noise including the quantization noise (QN). Moreover, several assumptions on the QN are investigated in the proposed method. Based on the output SNR, we compare different variations of the proposed method with the conventional BMVDR beamformer. The results confirm the improved performance of the proposed method.
Landscape Diversity: Multiple-Use Landscapes for Reclaimed Phosphatic Clay Areas (2006)

The intent of this document is to explore the benefits of using reclaimed phosphatic clay areas — a result of phosphate mining in central Florida — for multiple purposes to add to the local economy and the sustainability of the community and to take advantage of the clay resource for environmental and agricultural purposes. This document is written as a concept paper, which integrates information learned about phosphatic clay. This document is SL 229, a fact sheet of the Soil and Water Science Department, UF/IFAS Extension. Original publication date September 2005.
IASBs bildande av ett regelverk för SME - ur ett svenskt perspektiv (2004)

Syftet med vår uppsats är att bidra med kunskap om IASBs arbete för små och medelstora företag för att utvärdera om svenska småföretag tas i beaktande i IASBs pågående normbildningsprocess gällande SME. Vi har använt oss av en induktiv metod och kvalitativa data. Vi har gjort en fallstudie av IASBs normbildningsprocess rörande SME-projektet. Teorin om normbildningsprocessen har varit vår utgångspunkt vid analysen. Teorin om normbildningsprocessen har vidare utökats med faktorer som politik och kultur. Uppsatsen kommer bland annat fram till att IASBs SME GAAP lämpar sig bättre för stora onoterade företag, än för små onoterade företag i Sverige. Detta för att de svenska småföretagen är mindre internationellt sett. IASB bör ändra namnet på sitt SME-projekt, då det inte är lämpat för små företag i alla länder. Vi antar att ett SME GAAP kommer att bildas på grund av de politiska påtryckningarna. Det finns ett stort hinder i att harmonisera olika länders redovisning som bygger på olika redovisningstraditioner och kulturer. Det är därför inte troligt att IASB kommer se till svenska småföretags redovisningsbehov i den mån att SME GAAP kan tillämpas av svenska småföretag.
Electronic Gas-Phase Spectrum of the Pentaacetylene Cation (2002)

The origin band of the A2Πu−X2Πg electronic transition of the linear pentaacetelyne cation, HC10H+, and isotopic derivatives, HC10D+ and DC10D+, has been recorded in the gas phase. The absorption spectrum was observed by cavity ring down spectroscopy through a supersonic planar plasma expansion. The spectrum comprises both spin−orbit components with resolved P- and R-branches. Contour fits allow the determination of ground and excited state spectroscopic constants.
CTRP3 Regulates Endochondral Ossification and Bone Remodeling During Fracture Healing (2019)

C1q/TNF-related protein 3 (CTRP3) is a cytokine known to regulate a variety of metabolic processes. Though previously undescribed in the context of bone regeneration, high throughput gene expression experiments in mice identified CTRP3 as one of the most highly upregulated genes in fracture callus tissue. Hypothesizing a positive regulatory role for CTRP3 in bone regeneration, we phenotyped skeletal development and fracture healing in CTRP3 knockout (KO) and CTRP3 overexpressing transgenic (TG) mice relative to wild-type (WT) control animals. CTRP3 KO mice experienced delayed endochondral fracture healing, resulting in abnormal mineral distribution, the presence of periosteal marrow compartments, and a nonunion-like state. Decreased osteoclast number was also observed in CTRP3 KO mice, whereas CTRP3 TG mice underwent accelerated callus remodeling. Gene expression profiling revealed a broad impact on osteoblast/osteoclast lineage commitment and metabolism, including arrested progression toward mature skeletal lineages in the KO group. A single systemic injection of CTRP3 protein at the time of fracture was insufficient to phenocopy the chronic TG healing response in WT mice. By associating CTRP3 levels with fracture healing progression, these data identify a novel protein family with potential therapeutic and diagnostic value. © 2019 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 38:00-19966, 2020.
Studies on copolymerization of n‐isopropylacrylamide and glycidyl methacrylate (2001)

Abstract Free‐radical homopolymerization of N ‐isopropyl acrylamide (NIPA, monomer 1 ) and copolymerizations of NIPA with glycidyl methacrylate (GMA, monomer 2 ) were conducted in deuterated dioxane at 70 °C. The conversion of the monomers was followed by 1 H NMR spectroscopy. After the polymerization reactions the polymers were precipitated and analyzed. Reactivity ratios were determined using both Fineman–Ross and extended Kelen–Tüdős methods. Values obtained by these two methods were r 1 = 0.39, r 2 = 2.69 and r 1 = 0.30, r 2 = 2.66, respectively. In both cases, r ∼ 1, which is indicative of an ideal copolymerization resulting in a first‐order Markov distribution of the monomers in the final copolymer. The compositional heterogeneities of the polymers were estimated by following the instantaneous copolymer compositions as functions of conversion. Given the different reactivities of the two monomers it is concluded that a copolymer with a homogeneous distribution of monomers may be obtained not by a batch reaction, but by slowly and continuously adding GMA into the polymerizing reaction mixture. © 2001 John Wiley &amp; Sons, Inc. J Polym Sci Part A: Polym Chem 39: 3716–3725, 2001
Controlling photonic spin Hall effect based on tunable surface plasmon resonance with an N−type coherent medium (2020)

We propose a scheme to control the spin Hall effect (SHE) of light reflected from a Kretschmann configuration containing an N-type coherent atomic medium. Owing to the excitation of surface plasmon resonance (SPR), enhanced spin splitting occurs in the reflection dip for TM-polarized incident light. The magnitude and sign of the transverse shifts of spin components depend on the system internal damping which is closely related to the absorption coefficient of atoms. There is an optimal absorption around which the spin components undergo large transverse displacements. We also show that the direction of the photonic spin accumulations can be switched between positive and negative values by adjusting the system parameters. In addition, the resonance angle of SPR varies linearly with the refractivity of the medium. We can therefore coherently control the peak position of the transverse shift. Compared to the conventional SPR-based systems, the proposed scheme provides a more flexible pathway for manipulating and enhancing the SHE of light without changing the structure. This tunable SHE may find applications in spin photonic devices.
PD‐L1 (SP142) expression in neoplastic cells predicts a poor prognosis for patients with intravascular large B‐cell lymphoma treated with rituximab‐based multi‐agent chemotherapy (2020)

The worse prognosis of the PD-L1<sup>+</sup> group might be caused by immune evasion mechanisms, which are linked to PD-L1 expression. Therefore, PD-L1<sup>+</sup> IVLBCL cases might be regarded as good candidates for targeted immunotherapy. We also highlighted the overlapping features of PD-L1<sup>+</sup> IVLBCL and PD-L1<sup>+</sup> eDLBCL. This result suggests that they should be regarded as one entity, immune evasion-related extranodal large B-cell lymphoma.