gebhart/patrepeval huggingface dataset:
Production of a polymer with highly anisotropic conductivity and structure by Co-electroprecipitation of an imide anion radical and polycation (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTProduction of a polymer with highly anisotropic conductivity and structure by Co-electroprecipitation of an imide anion radical and polycationLarry L. Miller, Chuan Jiang Zhong, and Paul KasaiCite this: J. Am. Chem. Soc. 1993, 115, 14, 5982–5990Publication Date (Print):July 1, 1993Publication History Published online1 May 2002Published inissue 1 July 1993https://pubs.acs.org/doi/10.1021/ja00067a013https://doi.org/10.1021/ja00067a013research-articleACS PublicationsRequest reuse permissionsArticle Views365Altmetric-Citations49LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Signal Processing and Analysis Methods in Nuclear Quadrupole Resonance Spectroscopy (2018)

The purpose of this paper is to review the signal processing and analysis methods applied in nuclear quadrupole resonance (NQR) spectroscopy. NQR is a radio frequency spectroscopic technique used for detecting solid state compounds containing quadrupolar nuclei, in applications ranging from chemical analysis to explosive and drugs detection. This paper presents the principle of NQR, its applications, the detection methods and an overview of the research done in the field of signal processing and analysis using this technique. Different solutions are described, starting from the techniques developed initially up to state-of-the-art detection algorithms. These are presented in chronological order, also discussing their principles, advantages and disadvantages. This paper proposes several directions for future research and suggests machine learning as a next step in NQR signal analysis.
Real-time stabilization and tracking of a four rotor mini-rotorcraft (2003)

In this paper, we present a controller design and its implementation on a mini-rotorcraft having 4 rotors. The dynamic model is obtained via a Lagrange approach. Experiment results show good performance of the proposed non-linear controller based on nested saturation.
Geodesic Learning (2008)

In this paper we develop a new algorithm for estimating the geodesic between points in a point cloud. Geodesics are useful in dimensionality reduction and data analysis. The algorithm exploits data locally, and results in a distance minimizing curve. The convergence was experimentally verified in a toy (swiss roll) and 'semitoy' (rendered faces) data set.
Sampled Analog Optical Links (2009)

We present a new intensity-modulated analog optical link architecture in which a pulsed optical carrier replaces the standard low-noise continuous-wave laser. Through a time-domain analysis of the sampled link architecture, we show that the link performance metrics reduce to those of a conventional analog optical link in the absence of photodiode nonlinearity. Experimental measurements of the link gain and third-order nonlinearity are presented, emphasizing the link performance as a function of received photocurrent. The work presented here demonstrates that the performance of sampled analog optical links rivals that of the conventional architecture, even in the presence of significant photodiode nonlinearity.
ChemInform Abstract: Regioselective Formation of Fluorohydrins and Their Stereoselective Conversion to Fluoroolefins. (1990)

Abstract Tosylated fluorohydrins such as (III) are obtained by HF addition to oxiranes such as (I) using the pyridine‐HF complex followed by tosylation.
Will consuming datura prevent SARS-CoV-2 infection (2020)

The Datura stramonium shrub is widely distributed in Asia, 
Africa, and the Americas. The fact that it has spherical, 
prickly fruit (and is, therefore, also known as thorn apple) 
that resembles SARS-CoV-2 with its spike protein is only a 
coincidence. There is no evidence to suggest that the plant 
or any of its parts have antiviral properties.
Antifungal Agents1 (1955)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAntifungal Agents1Stephen B. Coan and Dominick PapaCite this: J. Am. Chem. Soc. 1955, 77, 9, 2402–2404Publication Date (Print):May 1, 1955Publication History Published online1 May 2002Published inissue 1 May 1955https://doi.org/10.1021/ja01614a013RIGHTS & PERMISSIONSArticle Views146Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (351 KB) Get e-Alerts Get e-Alerts
Energy macromodeling of embedded operating systems (2005)

As embedded systems get more complex, deployment of embedded operating systems (OSs) as software run-time engines has become common. In particular, this trend is true even for battery-powered embedded systems, where maximizing battery life is a primary concern. In such OS-driven embedded software, the overall energy consumption depends very much on which OS is used and how the OS is used. Therefore, the energy effects of the OS need to be studied in order to design low-energy systems effectively.In this paper, we discuss the motivation for performing OS energy characterization and propose a methodology to perform the characterization systematically. The methodology consists of two parts. The first part is analysis , which is concerned with identifying a set of components that can be used to characterize the OS energy consumption, called energy characteristics . The second part is macromodeling , which is concerned with obtaining quantitative macromodels for the energy characteristics. It involves the process of experiment design, data collection, and macromodel fitting. The OS energy macromodels can be used conveniently as OS energy estimators in high-level or architectural optimization of embedded systems for low-energy consumption.As far as we know, this work is the first attempt to systematically tackle energy macromodeling of an embedded OS. To demonstrate our approach, we present experimental results for two well-known embedded OSs, namely, μC/OS and embedded Linux OS.
Die VWL in Deutschland und den USA: eine ländervergleichende Analyse (2018)

Die Studie erfasst in Deutschland 569 (Vollerhebung) und in den USA 570 (Stichprobe) VWL-Universitätsprofessor_innen an 102 Standorten. Der Frauenanteil ist in Deutschland (13,36%) und in den USA (12,81%) gering. In beiden Ländern nimmt die mikroökonomisch orientierte Forschung eine dominante Stellung ein. Über 90 % der Professor_innen folgen dem ökonomischen Mainstream. Abweichende, heterodoxe Sichtweisen sind v.a. an kleinen Universitäten vertreten. Die Trennung zwischen Mainstream und Heterodoxie ist in den USA weiter fortgeschritten. Wesentliche inhaltliche und methodische Veränderungen innerhalb des Mainstreams betreffen v.a. die Verhaltensökonomie und Experimentelle Ökonomie. Die jüngere Generation in Deutschland ist noch stärker an der Mikroökonomie und am ökonomischen Mainstream orientiert; ordoliberale Ideen verlieren an Bedeutung. Die außerakademische Vernetzung erfolgt in Deutschland über Wirtschaftsforschungsinstitute. Zudem engagieren sich viele deutsche Ökonom_innen in ordo- bzw. neoliberalen Think Tanks. In den USA existiert eine klare Blockbildung aus demokratisch vs. republikanisch orientierten Ökonom_innen auf medial-politischer Ebene, wobei der demokratische Block deutlich größer ist. Demgegenüber sind konservative und libertäre Think Tanks größer und umfangreicher vernetzt. Deutsche wirtschaftswissenschaftliche Beratungsgremien weisen auf Personenebene eine ausgeprägte ordoliberale Schlagseite auf.
Prospective serum metabolomic profiling of lethal prostate cancer (2019)

Impaired metabolism may play an important role in the pathogenesis of lethal prostate cancer, yet there is a paucity of evidence regarding the association. We conducted a large prospective serum metabolomic analysis of lethal prostate cancer in 523 cases and 523 matched controls nested within the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study. Median time from baseline fasting serum collection to prostate cancer death was 18 years (maximum 30 years). We identified 860 known biochemicals through an ultrahigh-performance LC-MS/MS platform. Conditional logistic regression models estimated odds ratios (OR) and 95% confidence intervals of risk associated with 1-standard deviation (s.d.) increases in log-metabolite signals. We identified 34 metabolites associated with lethal prostate cancer with a false discovery rate (FDR) < 0.15. Notably, higher serum thioproline, and thioproline combined with two other cysteine-related amino acids and redox metabolites, cystine and cysteine, were associated with reduced risk (1-s.d. OR = 0.75 and 0.71, respectively; p ≤ 8.2 × 10<sup>-5</sup> ). By contrast, the dipeptide leucylglycine (OR = 1.36, p = 8.2 × 10<sup>-5</sup> ), and three gamma-glutamyl amino acids (OR = 1.28-1.30, p ≤ 4.6 × 10<sup>-4</sup> ) were associated with increased risk of lethal prostate cancer. Cases with metastatic disease at diagnosis (n = 179) showed elevated risk for several lipids, including especially the ketone body 3-hydroxybutyrate (BHBA), acyl carnitines, and dicarboxylic fatty acids (1.37 ≤ OR ≤ 1.49, FDR < 0.15). These findings provide a prospective metabolomic profile of lethal prostate cancer characterized by altered biochemicals in the redox, dipeptide, pyrimidine, and gamma-glutamyl amino acid pathways, whereas ketone bodies and fatty acids were associated specifically with metastatic disease.
A novel technique for the in situ calibration and measurement of friction with the atomic force microscope (2005)

Presented here is a novel technique for the in situ calibration and measurement of friction with the atomic force microscope that can be applied simultaneously with the normal force measurement. The method exploits the fact that the cantilever sits at an angle of about 10° to the horizontal, which causes the tip (or probe) to slide horizontally over the substrate as a normal force run is performed. This sliding gives rise to an axial friction force (in the axial direction of the cantilever), which is measured through the difference in the constant compliance slopes of the inward and outward traces. Traditionally, friction is measured through lateral scanning of the substrate, which is time consuming, and requires an ex situ calibration of both the torsional spring constant and the lateral sensitivity of the photodiode detector. The present method requires no calibration other than the normal spring constant and the vertical sensitivity of the detector, which is routinely done in the force analysis. The present protocol can also be applied to preexisting force curves, and, in addition, it provides the means to correct force data for cantilevers with large probes.
Generalized OFDM (GOFDM) for ultra-high-speed optical transmission (2011)

We propose a coded N-dimensional modulation scheme suitable for ultra-high-speed serial optical transport. The proposed scheme can be considered as a generalization of OFDM, and hence, we call it as generalized OFDM (GOFDM). In this scheme, the orthogonal subcarriers are used as basis functions and the signal constellation points are defined over this N-dimensional linear space. To facilitate implementation, we propose using N-dimensional pulse-amplitude modulation (ND-PAM) as the signal constellation diagram, which is obtained as the N-ary Cartesian product of one-dimensional PAM. In conventional OFDM, QAM/PSK signal constellation points are transmitted over orthogonal subcarriers and then they are multiplexed together in an OFDM stream. Individual subcarriers, therefore, carry N parallel QAM/PSK streams. In the proposed GOFDM scheme instead, an N-dimensional signal constellation point is transmitted over all N subcarriers simultaneously. When some of the subcarriers are severely affected by channel impairments, the constellation points carried by those subcarriers may be lost in the conventional OFDM. In comparison, under such conditions, the overall signal constellation point will face only small distortion in GOFDM and it can be recovered successfully using the information on the other high fidelity subcarriers. Furthermore, because the channel capacity is a logarithmic function of signal-to-noise ratio but a linear function of the number of dimensions, the spectral efficiency of optical transmission systems can be improved with GOFDM.
Coupled-mode theory for Bose-Einstein condensates (2000)

We apply the concepts of nonlinear guided-wave optics to a Bose-Einstein condensate (BEC) trapped in an external potential. As an example, we consider a parabolic double-well potential and derive coupled-mode equations for the complex amplitudes of the BEC macroscopic collective modes. Our equations describe different regimes of the condensate dynamics, including the nonlinear Josephson effect for any separation between the wells. We demonstrate macroscopic self-trapping for both repulsive and attractive interactions, and confirm our results by direct numerical solution of the Gross-Pitaevskii-equation.
On the neuronal circuitry mediating l-DOPA-induced dyskinesia (2018)

With the advent of rodent models of L-DOPA-induced dyskinesia (LID), a growing literature has linked molecular changes in the striatum to the development and expression of abnormal involuntary movements. Changes in information processing at the striatal level are assumed to impact on the activity of downstream basal ganglia nuclei, which in turn influence brain-wide networks, but very little is actually known about systems-level mechanisms of dyskinesia. As an aid to approach this topic, we here review the anatomical and physiological organisation of cortico-basal ganglia-thalamocortical circuits, and the changes affecting these circuits in animal models of parkinsonism and LID. We then review recent findings indicating that an abnormal cerebellar compensation plays a causal role in LID, and that structures outside of the classical motor circuits are implicated too. In summarizing the available data, we also propose hypotheses and identify important knowledge gaps worthy of further investigation. In addition to informing novel therapeutic approaches, the study of LID can provide new clues about the interplay between different brain circuits in the control of movement.
GPUQP (2007)

We present GPUQP, a relational query engine that employs both CPUs and GPUs (Graphics Processing Units) for in-memory query co-processing. GPUs are commodity processors traditionally designed for graphics applications. Recent research has shown that they can accelerate some database operations orders of magnitude over CPUs. So far, there has been little work on how GPUs can be programmed for heavy-duty database constructs, such as tree indexes and joins, and how well a full-fledged GPU query co-processor performs in comparison with their CPU counterparts. In this work, we explore the design decisions in using GPUs for query co-processing using both a graphics API and a general purpose programming model. We then demonstrate the processing flows as well as the performance results of our methods.
Supramolecular organogels and nanowires based on a V-shaped cyanostilbene amide derivative with aggregation-induced emission (AIE) properties (2013)

A V-shaped cyanostilbene amide derivative (BPBIA) containing tert-butyl groups has been designed and synthesized. It was employed as building blocks to fabricate one-dimensional (1D) organic nano- or microstructures. BPBIA shows excellent self-assembling properties. First, it can readily self-assemble into gels with nanofiber structures in several kinds of organic solvents through the cooperative effect of intermolecular hydrogen bonding, π–π stacking and cyano interactions. Second, size controllable well-defined 1D nanowires with lengths up to several millimeters also have been fabricated based on the slow evaporation approach. More importantly, the individually dispersed nanowires with uniform morphology are independent of substrates and solvents. Compared with the solution, both the generated nanofibrous gels and the nanowires exhibited significantly enhanced emission, showing typical aggregation-induced emission (AIE) behavior. The single-crystal X-ray analysis provided a reasonable explanation for the formation of 1D nano- or microstructures. Thus, the molecule could provide ways for the easy fabrication of highly emissive nano- and microstructures for use in organic optoelectronics.
Listeria monocytogenes-infected human monocytic derived dendritic cells activate Vγ9Vδ2 T cells independently of HMBPP production (2021)

Gamma-delta (γδ) T cells express T cell receptors (TCR) that are preconfigured to recognize signs of pathogen infection. In primates, γδ T cells expressing the Vγ9Vδ2 TCR innately recognize (E)-4-hydroxy-3-methyl-but- 2-enyl pyrophosphate (HMBPP), a product of the 2-C-methyl-D-erythritol 4- phosphate (MEP) pathway in bacteria that is presented in infected cells via interaction with members of the B7 family of costimulatory molecules butyrophilin (BTN) 3A1 and BTN2A1. In humans, Listeria monocytogenes (Lm) vaccine platforms have the potential to generate potent Vγ9Vδ2 T cell recognition. To evaluate the activation of Vγ9Vδ2 T cells by Lm-infected human monocyte-derived dendritic cells (Mo-DC) we engineered Lm strains that lack components of the MEP pathway. Direct infection of Mo-DC with these bacteria were unchanged in their ability to activate CD107a expression in Vγ9Vδ2 T cells despite an inability to synthesize HMBPP. Importantly, functional BTN3A1 was essential for this activation. Unexpectedly, we found that cytoplasmic entry of Lm into human dendritic cells resulted in upregulation of cholesterol metabolism in these cells, and the effect of pathway regulatory drugs suggest this occurs via increased synthesis of the alternative endogenous Vγ9Vδ2 ligand isoprenyl pyrophosphate (IPP) and/or its isomer dimethylallyl pyrophosphate (DMAPP). Thus, following direct infection, host pathways regulated by cytoplasmic entry of Lm can trigger Vγ9Vδ2 T cell recognition of infected cells without production of the unique bacterial ligand HMBPP.
United States Overseas Basing: An Anatomy of the Dilemma (1990)

Introduction The Rise and Decline of the Overseas Basing System Today's Overseas Basing System The Costs, Value, and Future of Overseas Basing The Next Ten Years: The Basing Crisis and Some Solutions Appendix A: The Base Site Data Base Appendix B: Potential Base-Operations Networks Bibliography Index
Measurement of electrons from heavy-flavour hadron decays as a function of multiplicity in p-Pb collisions at $$ \sqrt{s_{\mathrm{NN}}} $$ = 5.02 TeV (2020)

Abstract The multiplicity dependence of electron production from heavy-flavour hadron decays as a function of transverse momentum was measured in p-Pb collisions at $$ \sqrt{s_{\mathrm{NN}}} $$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msqrt> <mml:msub> <mml:mi>s</mml:mi> <mml:mi>NN</mml:mi> </mml:msub> </mml:msqrt> </mml:math> = 5 . 02 TeV using the ALICE detector at the LHC. The measurement was performed in the centre-of-mass rapidity interval − 1 . 07 &lt; y cms &lt; 0 . 14 and transverse momentum interval 2 &lt; p T &lt; 16 GeV /c . The multiplicity dependence of the production of electrons from heavy-flavour hadron decays was studied by comparing the p T spectra measured for different multiplicity classes with those measured in pp collisions ( Q pPb ) and in peripheral p-Pb collisions ( Q cp ). The Q pPb results obtained are consistent with unity within uncertainties in the measured p T interval and event classes. This indicates that heavy-flavour decay electron production is consistent with binary scaling and independent of the geometry of the collision system. Additionally, the results suggest that cold nuclear matter effects are negligible within uncertainties, in the production of heavy-flavour decay electrons at midrapidity in p-Pb collisions.
Hybrid Perovskite: Solid-State NMR Investigation From Room To Very Low Temperatures (2016)

International audience
Final analysis of a safety and efficacy trial of preoperative sequential chemoradiation therapy for the nonsurgical treatment (NST) in early breast cancer (EBC): Japan Clinical Oncology Group Trial (JCOG0306). (2010)

552 Background: The combination of preoperative anthracycline-containing regimen and taxane can obtain a good pathologic complete response (pCR) rate for patients (pts) with EBC. To pursue higher pCR rate with maintaining good systemic control may lead to the NST in the future. The objective of this trial is to determine whether the addition of radiation therapy (RT) to chemotherapy (CT) can surpass the pCR rate of 50% as the first step of turning the NST into reality. Methods: We conducted a safety and efficacy trial of CT (4 courses of doxorubicin and cyclophosphamide [60/600mg/m2] followed by 12 courses of weekly paclitaxel [80mg/m2]) and RT (whole breast 45Gy + boost 10Gy) sequentially as a primary therapy in pts with stage I-IIIA (5.0cm ≥ tumor size ≥ 2.0cm) breast cancer (BC). All pts received mastectomy or lumpectomy 12-16 weeks after completion of RT to maximize the effect of RT. Primary endpoint was pCR rate. pCR was assessed by the central pathological review board. Results: Between June 2004 and April 2005, 108 pts were enrolled. Median age was 50 years (range 23-69). 62% (67/108) were hormone receptor (HR) +, and 31% (34/108) had HER2+. 36% of the entire population achieved a pCR. The pCR rate was 57% in pts with HR-/HER2+, and 52% in triple-negative pts, respectively. While 7% of HR–/HER2+ pts recurred, higher incidence of recurrence (24%) was observed in triple-negative pts in follow-up of 4.5 years. The rate of breast- conserving surgery was 91% (96/106). One pt received debridement for radiation associated necrosis 3 months after lumpectomy. Other toxicities were mild to moderate. Conclusions: Preoperative sequential chemoradiation therapy did not increase the risk of operative complications and could achieve high rate of breast-conserving surgery, even though expected % pCR was not achieved. Choosing the subgroup of EBC can be necessary to realize NST in the next step. Characteristics No. of pts pCR rate No. of recurrence events HR+/HER2- 46 24% 10 (22%) HR+/HER2+ 20 40% 3 (15%) HR-/HER2- 25 52% 6 (24%) HR-/HER2+ 14 57% 1 (7%) No significant financial relationships to disclose.