gebhart/patrepeval huggingface dataset:
Significance of the width of keratinized mucosa on peri-implant health (2015)

In implant therapy, the adequate state of peri-implant tissue health and soft-tissue aesthetics is the essential criterion of restorative success. The need for keratinized mucosa for the maintenance of peri-implant health and soft-tissue integration remains a debated issue. The aim of this paper is to provide a narrative review of the current literature concerning the significance of keratinized mucosa with respect to the clinical parameters of monitoring oral hygiene practice and tissue status. The published studies revealed that there were conflicting results with regard to the influence of keratinized mucosa on plaque score and soft-tissue inflammation. Most studies showed that the amount of soft-tissue recession was significantly increased at implant sites with narrow keratinized mucosa, but the amount of keratinized mucosa had little effect on deepening of peri-implant pockets. The evidence related to the effect of keratinized mucosa on the changes of attachment or bone levels is limited, and conclusions could not be drawn at present. Further, this review found that a band of keratinized mucosa was not absolutely necessary for the maintenance of peri-implant tissue, whereas lack of adequate keratinized mucosa around the implant might impede proper oral hygiene performance and compromise the aesthetic results. In conclusion, because there is a wide variety of clinical features in patients pursuing implant therapy, individual consideration of treatment strategies for the patient with minimal keratinized mucosa is recommended.
A Master-Slave Particle Swarm Optimization Algorithm for Solving Constrained Optimization Problems (2006)

Penalty function based PSO converts constrained optimization problems into non-constrained optimization problems, but slow convergence and premature convergence easily happen because of inappropriate penalty coefficients. Modified PSO by tracking best feasible particle can not facilitate particles exploring unknown feasible region from known infeasible region, so the global exploration ability is greatly limited. Therefore, finding better unknown feasible solution by flying through infeasible region is critical to the performance of PSO. This paper proposes master-slave particle swarm optimization (MSPSO), a novel approach for solving constrained optimization problems, in which particles in master swarm fly toward better feasible particles, particles in slave swarm fly toward better infeasible particles, and particles in two swarms help each other flying by sharing information of better feasible and infeasible particles. The proposed algorithm was tested on 11 benchmark constrained optimization problems. The test results show that MSPSO can significantly improve the globe exploration ability and effectively avoid being trapped into local optimum. By comparison with other evolutionary algorithms, MSPSO performs better for constrained optimization problems
Reactive extraction of bio‐based 3‐hydroxypropionic acid assisted by hollow‐fiber membrane contactor using TOA and Aliquat 336 in n‐decanol (2016)

Abstract BACKGROUND Reactive liquid–liquid extraction is a promising technique for the direct recovery of carboxylic acids from bioconversion media. This work focused on the optimization of 3‐hydroxypropionic acid (3‐ HP ) reactive extraction assisted by hollow‐fiber membrane contactor ( HFMC ), using tri‐ n ‐octylamine ( TOA ) and Aliquat 336 as extractants in n ‐decanol, and on its practical application for the recovery of 3‐ HP obtained from glycerol bioconversion by Lactobacillus reuteri . RESULTS The results underlined the influence of the initial pH and 3‐ HP concentration of the aqueous medium and the impact of extractant phase composition on the extraction performances. The highest distribution coefficient of 3‐ HP ( K D = 13.0) was observed at pH = 3 with 10% v/v TOA mixed with 10% v/v Aliquat 336 in n ‐decanol. This study showed that the acid concentration and the ratio of amines used between TOA and Aliquat 336 in n ‐decanol did not have a great impact on the K D during 3‐ HP reactive extraction, whereas it had an influence on the extraction kinetics. Moreover, 3‐ HP reactive extraction assisted by HFMC from real bioconversion broth with glycerol as the substrate was shown to be feasible, with the same order of magnitude of extraction kinetics but with a lower K D compared with reactive extraction using model broth. CONCLUSIONS 3‐ HP was predominantly extracted from the bioconversion broth, confirming the high selectivity of the extraction process studied and the high potential of this approach applied to the biotechnological production of 3‐ HP . © 2016 Society of Chemical Industry
Anti-icing Coating with an Aqueous Lubricating Layer (2014)

In this paper, an anti-icing coating with an aqueous lubricating layer is reported. This anti-icing coating can be directly applied to various substrates, and the ice adhesion strength on the coated surfaces can be lowered greatly as compared to uncoated substrates. We demonstrate for the first time that the formed ice on this anti-icing coating can be blown off by a wind action in the wind tunnel with a controlled temperature and wind velocity. Moreover, the low ice adhesion of the anti-icing coating can be maintained even when the temperature is lowered to -53 °C. The robustness and durability of the anti-icing coating are proved by the icing/de-icing experiments. The results show that the anti-icing coating with an aqueous lubricating layer is of great promise for practical applications.
Brief announcement (2009)

Designing an overlay network for publish/subscribe communication in a system where nodes may subscribe to many different topics of interest is of fundamental importance. For scalability and efficiency, it is important to keep the degree of the nodes in the publish/subscribe system low. It is only natural then to formalize the following problem: Given a collection of nodes and their topic subscriptions connect the nodes into a graph which has low average and maximum degree and in such a way that for each topic t, the graph induced by the nodes interested in t is connected. We present the first polynomial time parameterized sublinear approximation algorithm for this problem.
Turbulence Model Dependencies on Conjugate Simulation of Flow and Heat Conduction (2007)

This paper discusses the influences of the turbulence model selection on the heat transfer prediction in the conjugate simulation of flow and heat conduction. It is known that the heat transfer prediction by the flow simulation based on RANS is dependent upon the turbulence model. Common difficulties are the anomalous production of turbulent kinetic energy in a flow with large rates of strain and the laminar-turbulent transition, both of which are persistent aspects in typical turbine cascade flow. Similar and possibly greater impact is expected when these turbulence models are applied to the conjugate simulation of flow and heat conduction. An anomaly treatment called a time-scale bound is applied to the low Reynolds number k-ω and the SST turbulence models installed in the common CFD platform UPACS. The turbulence model dependencies on the conjugate simulation of flow and heat conduction are investigated in an axisymmetric turbulent jet impingement and the 2D turbine cascade vanes.
Mutating the “primer grip” of p66 HIV-1 reverse transcriptase implicates tryptophan-229 in template-primer utilization (1994)

"BcgI cassette" mutagenesis was used to prepare variants of p66 human immunodeficiency virus (HIV)-1 reverse transcriptase with amino acid substitutions between residues Glu224 and Trp229. Mutant polypeptides were reconstituted in vitro with wild type p51 to generate the "selectively mutated" heterodimer series p66(224A)/p51-p66(229A)/p51. Purified enzymes were characterized with respect to dimerization, DNA polymerase, RNase H, and tRNA(Lys-3) binding. The combined analyses indicate that while alteration of p66 residues Glu224-Leu228 has minimal consequences, the DNA polymerase activities of mutant p66(229A)/p51 are impaired. DNase I footprinting illustrates that this mutant does not form a stable replication complex with a model template-primer. In vivo studies indicate that the equivalent mutation eliminates viral infectivity, suggesting a contribution of Trp229 toward architecture of the p66 primer grip.
Caching and database scaling in distributed shared-nothing information retrieval systems (1993)

A common class of existing information retrieval system provides access to abstracts. For example Stanford University, through its FOLIO system, provides access to the INSPECT database of abstracts of the literature on physics, computer science, electrical engineering, etc. In this paper this database is studied by using a trace-driven simulation. We focus on physical index design, inverted index caching, and database scaling in a distributed shared-nothing system. All three issues are shown to have a strong effect on response time and throughput. Database scaling is explored in two ways. One way assumes an “optimal” configuration for a single host and then linearly scales the database by duplicating the host architecture as needed. The second way determines the optimal number of hosts given a fixed database size.
Automatically constructing a dictionary for information extraction tasks (1993)

Knowledge-based natural language processing systems have achieved good success with certain tasks but they are often criticized because they depend on a domain-specific dictionary that requires a great deal of manual knowledge engineering. This knowledge engineering bottleneck makes knowledge-based NLP systems impractical for real-world applications because they cannot be easily scaled up or ported to new domains. In response to this problem, we developed a system called AutoSlog that automatically builds a domain-specific dictionary of concepts for extracting information from text. Using AutoSlog, we constructed a dictionary for the domain of terrorist event descriptions in only 5 person-hours. We then compared the AutoSlog dictionary with a hand-crafted dictionary that was built by two highly skilled graduate students and required approximately 1500 person-hours of effort. We evaluated the two dictionaries using two blind test sets of 100 texts each. Overall, the AutoSlog dictionary achieved 98% of the performance of the hand-crafted dictionary. On the first test set, the AutoSlog dictionary obtained 96.3% of the performance of the hand-crafted dictionary. On the second test set, the overall scores were virtually indistinguishable with the AutoSlog dictionary achieving 99.7% of the performance of the handcrafted dictionary.
An efficient depalletizing system based on 2D range imagery (2002)

We propose an efficient approach towards the solution of the de-palletizing problem, based on active vision. We describe a system comprising an industrial robot and a time of flight laser sensor, which performs the depalletizing task in real time, and independently of lighting conditions. In our case, the target objects are solid boxes of known identical dimensions, neatly layered but with arbitrary orientation within a layer, which are all placed on a platform. The layered structure of the target platform allows for 2D imagery. The system locates the position of the boxes by tracking one of the corners they expose to the laser source. The system locates the desired corners by applying the scan line approximation technique, adapted to fit the needs of our application, to the 2D input data. The advantages of our system over existing applications are its simplicity, robustness, speed and ease of installation.
Innate Immunity and Mobilization of Hematopoietic Stem Cells (2017)

We will present data from our laboratory that initiation of complement cascade activation and subsequently activation of the coagulation cascade during mobilization process are dependent on mannan-binding lectin (MBL). The mannan-binding pathway activates MBL-associated serine proteases (MASP-1 and MASP-2) that cleave the third complement component C3 and prothrombin. Cleavage of C3 leads to formation of classical C5 convertase and cleavage of prothrombin generates thrombin, which has "C5-like convertase" activity. Finally, both C5 convertase and thrombin cleave the fifth complement component C5, and activate distal part of the complement cascade that is crucial for egress of HSCPs from bone marrow niches into peripheral blood.
Highly Reliable Stereo Matching Based on Adaptive Window-Size Selection and Its VLSI Implementation (2003)

High-speed acquisition of reliable three-dimensional (3-D) information plays an essential role in real-world intelligent systems such as intelligent robots and highly-safe intelligent vehicles. Stereo vision is a well-known method for 3-D instrumentation. A major issue of stereo vision is to establish reliable correspondence between images. This paper presents a reliable stereo-matching algorithm based on SAD (Sum of Absolute Differences) computation. Reliable correspondence can be established by selecting a desirable window size of the SAD computation based on the uniqueness of a minimum of the SAD graph. Moreover, to increase reliability in matching, edge information is efficiently used for selecting the window size. A pixel-serial and window-parallel architecture is also presented to achieve 100% utilization of processing elements. The performance of the VLSI processor is evaluated to be 1500 times higher than that of a general-purpose processor.
Monolithic multisegment mode locked DBR laser for wavelength tunable picosecond pulse generation (2002)

Monolithic active/passive mode locked DBR lasers for 4/spl times/10 Gb/s OTDM application at 1.55 /spl mu/m are realized by low cost 2"-technology. The devices show excellent performance at STM-64 frequency: they deliver nearly time-bandwidth limited (<0.4) and wavelength tunable (4.3 nm range) optical RZ pulses of down to 8 ps pulse width.
A case study on determining air monitoring requirements in a radioactive materials handling area (1993)

A technical, defensible basis for the number and placement of air sampling instruments in a radioactive materials handling facility was developed. Historical air sampling data, process and physicochemical knowledge, qualitative smoke dispersion studies with video documentation, and quantitative trace gas dispersion studies were used to develop a strategy for number and placement of air samplers. These approaches can be used in other facilities to provide a basis for operational decisions. The requirements for retrospective sampling, personal sampling, and real-time monitoring are included. Other relevant operational decisions include selecting the numbers, placement, and appropriate sampling rates for instruments, identifying areas of stagnation or recirculation, and determining the adequacy and efficiency of any sampling transport lines. Justification is presented for using a graded approach to characterizing the workplace and determining air sampling and monitoring needs.
Robust Design Through the Use of a Hybrid Genetic Algorithm (2002)

In this paper we present a hybrid optimization approach to perform robust design. The motivation for this work is the fact that many realistic engineering systems are mutimodal in nature with multiple local optima, and moreover may have one or more uncertain design parameters. The approach that is presented utilizes both local and global optimization algorithms to find good design points more efficiently than either could alone. The mean and variance of the objective function at a design point is calculated using Monte Carlo simulation and is used to drive the optimization process. To demonstrate the usefulness of this approach a case study is considered involving the design of a beam with dimensional uncertainty.
A Combined DPE/Epoxide Termination Strategy for Hydroxyl End-Functional Poly(2-vinylpyridine) and Amphiphilic AB2-Miktoarm Stars (2011)

ADVERTISEMENT RETURN TO ISSUEPREVNoteA Combined DPE/Epoxide Termination Strategy for Hydroxyl End-Functional Poly(2-vinylpyridine) and Amphiphilic AB2-Miktoarm StarsAdrian Natalello, Christoph Tonhauser, Elena Berger-Nicoletti, and Holger Frey*View Author Information Institute of Organic Chemistry, Johannes Gutenberg-University, Mainz, Duesbergweg 10-14, D-55099 Mainz, GermanyE-mail: [email protected]Cite this: Macromolecules 2011, 44, 24, 9887–9890Publication Date (Web):November 30, 2011Publication History Received25 October 2011Published online30 November 2011Published inissue 27 December 2011https://pubs.acs.org/doi/10.1021/ma2023793https://doi.org/10.1021/ma2023793brief-reportACS PublicationsCopyright © 2011 American Chemical SocietyRequest reuse permissionsArticle Views1004Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Addition reactions,Ethers,Hydroxyls,Polymers,Star polymers Get e-Alerts
Combination therapies augment the anti-tumor activity of agonist CD27 mAb in human CD27 transgenic mouse models (2013)

Meeting abstracts CDX-1127 is a fully human antibody to CD27, a TNF receptor superfamily member expressed on the majority of T cells and subsets of NK cells and B cells. We have previously characterized the co-stimulatory activities of CDX-1127 with human T cell cultures and a human CD27 transgenic
Synthesis of N-Fmoc-O- (N‘-Boc-N‘-methyl)-aminohomoserine, an Amino Acid for the Facile Preparation of Neoglycopeptides (2002)

The synthesis of N-Fmoc-O-(N'-Boc-N'-methyl)-aminohomoserine in 35% overall yield from l-homoserine is described. This amino acid can be efficiently incorporated into peptides using Fmoc-chemistry-based solid-phase peptide synthesis, and the resulting peptides can be chemoselectively glycosylated at the aminooxy side chains to generate neoglycopeptides. The synthesis of this derivative greatly expands the availability of a previously developed neoglycopeptide synthesis strategy.
Effects of Pb substitution on the vortex state of oxygen-overdoped Bi2Sr2CaCu2O8+δ single crystal (2000)

We show that excessive Pb substitution of Bi in oxygen-overdoped BSCCO-2212 single crystal further reduces the anisotropy $({\ensuremath{\rho}}_{c}/{\ensuremath{\rho}}_{a}$ ratio) of the system in addition to enhancing disorder in its vortex system. These effects have led to the suppression of first-order vortex melting as well as a peculiar second-peak effect exhibiting a sensitive temperature dependence over an unusually broad temperature range. Our experimental data further reveal, in a Bi-based system, the presence of a disentangled vortex liquid phase separating the solid vortex from the entangled vortex liquid phase in the $H\ensuremath{-}T$ diagram constructed from the transport and magnetization data.
Genetic characterization of commercial Saccharomyces cerevisiae isolates recovered from vineyard environments (2007)

One hundred isolates of the commercial Saccharomyces cerevisiae strain Zymaflore VL1 were recovered from spontaneous fermentations carried out with grapes collected from vineyards located close to wineries in the Vinho Verde wine region of Portugal. Isolates were differentiated based on their mitochondrial DNA restriction patterns and the evaluation of genetic polymorphisms was carried out by microsatellite analysis, interdelta sequence typing and pulsed-field gel electrophoresis (PFGE). Genetic patterns were compared to those obtained for 30 isolates of the original commercialized Zymaflore VL1 strain. Among the 100 recovered isolates we found a high percentage of chromosomal size variations, most evident for the smaller chromosomes III and VI. Complete loss of heterozygosity was observed for two isolates that had also lost chromosomal heteromorphism; their growth and fermentative capacity in a synthetic must medium was also affected. A considerably higher number of variant patterns for interdelta sequence amplifications was obtained for grape-derived strains compared to the original VL1 isolates. Our data show that the long-term presence of strain VL1 in natural grapevine environments induced genetic changes that can be detected using different fingerprinting methods. The observed genetic changes may reflect adaptive mechanisms to changed environmental conditions that yeast cells encounter during their existence in nature.
Interferon Type I Downregulates Human Parainfluenza Virus Type 3-Induced Major Histocompatibility Complex Class II Expression (2002)

Human parainfluenza virus type 3 (HPIV3) induces major histocompatibility complex (MHC) class II expression in a signal transducer and activator of transcription-1 (STAT1)- and class II transactivator (CIITA)-independent manner. Interferon (IFN)-gamma, the potent inducer of MHC class II, on the other hand, requires both STAT1 and CIITA in the induction process. IFN-alpha/beta has been shown to inhibit the IFN-y-induced expression of MHC class II by targeting a step(s) downstream of CIITA. Here we report that IFN-alpha/beta also inhibits the CIITA-independent expression of HPIV3-induced MHC class II. The inhibitory role of IFN-alpha/beta on HPIV3-induced MHC class II was confirmed by using anti-IFN-alpha/beta antibody and mutant cell lines defective in the IFN signaling components STAT1 and STAT2. IFN-alpha/beta inhibits virus-induced MHC class II expression just as it does IFN-gamma-induced MHC class II. The inhibition by IFN-alpha/beta of MHC class II expression may play a regulatory role in virus induced autoimmune disease mediated by MHC class II aberrant expression.
Growth and Fabrication of GaN/InGaN Violet Light Emitting Diode on Patterned Sapphire Substrate (2014)

GaN/InGaN based violet light emitting diodes (LEDs), emitting at 430 nm, have been grown on conventional single side polished (SSP) and patterned sapphire substrates (PSS). Characteristics of the epitaxial wafers and subsequently fabricated LEDs have been analyzed. The photoluminescence (PL) peaks have been observed at 428.1 nm 426.1 nm for the epitaxial layers on SSP and PSS respectively. The PL intensity is 2.9 times higher in the case of PSS. The electroluminescence (EL) peaks have been observed at 430.78 nm and 430.35 nm for the LEDs on SSP and PSS respectively. The light output from LED fabricated on the PSS is 2.15 times higher than that of the LED on SSP at a forward current of 100 mA.
Diabetes Mellitus and Liver Transplantation (1993)

"Diabetes Mellitus and Liver Transplantation." Baylor University Medical Center Proceedings, 6(1), p. 22
Supplemental Materials and Methods from Histone Deacetylase Inhibitors Inhibit Rhabdomyosarcoma by Reactive Oxygen Species–Dependent Targeting of Specificity Protein Transcription Factors (2023)

&lt;p&gt;Supplemental Material and Methods.&lt;/p&gt;