gebhart/patrepeval huggingface dataset:
Long‐term phosphorus accumulation and removal efficiency in a land‐based wastewater treatment system in the UK (2018)

Abstract The study aims to assess the long‐term phosphorus (P) removal in a land treatment system (LTS) in the UK. Different sections of the site have been irrigated with wastewater effluent for different periods of time for up to 85 years. The amounts of P discharged and accumulated were calculated from historical data, estimations of water consumption, composition and soil measurement. The total P input during the study period was estimated to be 90 010 kg, the average P removal was 4% and there was no significant difference in the total P accumulated between plots irrigated for different periods, indicating that the sorption capacity of the soil might be saturated. Despite the low P retention rates in the LTS, there is no evidence that emissions from this system are affecting P concentrations in either the nearby river or the local chalk aquifer. Gaps remain, however, in performance optimisation and longevity forecasting.
Colloidal Cu/ZnO catalysts for the hydrogenation of carbon dioxide to methanol: investigating catalyst preparation and ligand effects (2017)

This paper reports on the influences of the catalyst preparation method and ligand effects for a series of highly active Cu/ZnO colloidal catalysts for the hydrogenation of CO<sub>2</sub> to methanol.
Brain Metabolite Levels in Sedentary Women and Non-contact Athletes Differ From Contact Athletes (2020)

White matter tracts are known to be susceptible to injury following concussion. The objective of this study was to determine whether contact play in sport could alter white matter metabolite levels in female varsity athletes independent of changes induced by long-term exercise. Metabolite levels were measured by single voxel proton magnetic resonance spectroscopy (MRS) in the prefrontal white matter at the beginning (In-Season) and end (Off-Season) of season in contact (<i>N</i> = 54, rugby players) and non-contact (<i>N</i> = 23, swimmers and rowers) varsity athletes. Sedentary women (<i>N</i> = 23) were scanned once, at a time equivalent to the Off-Season time point. Metabolite levels in non-contact athletes did not change over a season of play, or differ from age matched sedentary women except that non-contact athletes had a slightly lower <i>myo</i>-inositol level. The contact athletes had lower levels of <i>myo</i>-inositol and glutamate, and higher levels of glutamine compared to both sedentary women and non-contact athletes. Lower levels of <i>myo</i>-inositol in non-contact athletes compared to sedentary women indicates long-term exercise may alter glial cell profiles in these athletes. The metabolite differences observed between contact and non-contact athletes suggest that non-contact athletes should not be used as controls in studies of concussion in high-impact sports because repetitive impacts from physical contact can alter white matter metabolite level profiles. It is imperative to use athletes engaged in the same contact sport as controls to ensure a matched metabolite profile at baseline.
Partial and Total Wrist Arthrodesis in the Athlete (1998)

Patients who suffer intercarpal ligament injuries of the wrist can be treated by other soft tissue reconstruction or limited or total arthrodesis depending on the particular problem. A description of each of the partial and total wrist arthrodesis indications for athletes is given, including overall outcome parameters. Technical components of each of the types of surgery are also provided.
Fluxional η3-Allyl Derivatives of ansa-Scandocenes and an ansa-Yttrocene. Measurements of the Barriers for the η3 to η1 Process as an Indicator of Olefin Binding Energy to d0 Metallocenes (1999)

Variable-temperature 1H NMR spectroscopy indicates fluxional behavior for a number of group 3 metallocene allyl complexes. Spectral simulations and line shape analyses for the variable-temperature spectra indicate an allyl rearrangement mechanism involving rate-determining carbon−carbon double-bond dissociation from the metal center, i.e. an η3 to η1 change in coordination. Activation barriers to olefin dissociation have been determined for (η5-C5Me5)2Sc(η3-C3H5), meso-Me2Si(η5-3-CMe3-C5H3)2Sc(η3-C3H5), meso-Me2Si[η5-2,4-(CHMe2)2-C5H2]2Sc(η3-C3H5), meso-Me2Si{η5-3-[2-(2-Me)-adamantyl]-C5H3}2Sc(η3-C3H5), meso-Me2Si{η5-3-[2-(2-Me)-adamantyl]-C5H3}2Y(η3-C3H5), rac-Me2Si[η5-2,4-(CHMe2)2-C5H2]2Sc(η3-C3H5)), and R-(C20H12O2)Si(η5-2-SiMe3-4-CMe3-C5H2)2Sc(η3-C3H5): ΔG⧧ = 11−16 kcal mol-1 at ca. 300−350 K. Donor solvents do not significantly affect the rate of olefin dissociation. A second rearrangement mechanism that involves 180° rotation of the η3-C3H5 moiety has been found to operate in those metallocenes whose ancillary ligand arrays adopt rigid meso geometries. Line shape analysis indicates that the rate of η3-C3H5 rotation is generally more than 1 order of magnitude faster than olefin dissociation for a given meso metallocene. The data do not allow unambiguous assessments of the mechanism(s) for the fluxional behavior for the allyl derivatives of the racemic metallocenes. An X-ray structure determination for rac-Me2Si[η5-C5H2-2,4-(CHMe2)2]2Sc(η3-C3H5) has been carried out.
Systems-wide analysis of the GATC-binding nucleoid-associated protein Gbn and its impact on Streptomyces development (2021)

ABSTRACT Bacterial chromosome structure is organized by a diverse group of proteins collectively referred to as nucleoid-associated proteins (NAPs). Many NAPs have been well studied in Streptomyces, including Lsr2, HupA, HupS, and sIHF. Here, we show that SCO1839 represents a novel family of Actinobacteria NAPs and recognizes a consensus sequence consisting of GATC followed by (A/T)T. The protein was designated Gbn for G ATC- b inding N AP. Deletion of gbn led to alterations in development and antibiotic production in Streptomyces coelicolor . Chromatin immunoprecipitation sequencing (ChIP-Seq) detected more than 2800 binding regions, encompassing some 3600 GATCWT motifs, which comprise 55% of all such motifs in the S. coelicolor genome. DNA binding of Gbn in vitro increased DNA stiffness but not compaction, suggesting a role in regulation rather than chromosome organization. Transcriptomics analysis showed that Gbn binding generally leads to reduced gene expression. The DNA binding profiles were nearly identical between vegetative and aerial growth. Exceptions are SCO1311 and SCOt32, for a tRNA editing enzyme and a tRNA that recognises the rare leucine codon CUA, respectively, which nearly exclusively bound during vegetative growth. Taken together, our data show that Gbn is a highly pleiotropic NAP that impacts growth and development in streptomycetes. IMPORTANCE A large part of the chemical space of bioactive natural products is derived from Actinobacteria. Many of the biosynthetic gene clusters for these compounds are cryptic, in others words, they are expressed in nature but not in the laboratory. Understanding the global regulatory networks that control gene expression is key to the development of approaches to activate this biosynthetic potential. Chromosome structure has a major impact on the control of gene expression. In bacteria, the organization of chromosome structure is mediated by a diverse group of proteins referred to collectively as nucleoid-associated proteins (NAPs), which play an important role in the control of gene expression, nucleoid structure and DNA repair. We here present the discovery of a novel and extremely pleiotropic NAP, which we refer to as Gbn. Gbn is a sporulation-specific protein that occurs only in the Actinobacteria and binds to GATC sequences, with a subtle but broad effect on global gene expression. The discovery of Gbn is a new step towards better understanding of how gene expression and chromosome structure is governed in antibiotic-producing streptomycetes.
Data Supplement from Evidence for Molecular Differences in Prostate Cancer between African American and Caucasian Men (2023)

&lt;p&gt;Supplementary Figure Legend&lt;/p&gt;
Gas‐Phase Hydration of U(IV), U(V), and U(VI) Dioxo Monocations. (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
James-Stein state filtering algorithms (1998)

In 1961, James and Stein discovered a remarkable estimator that dominates the maximum-likelihood estimate of the mean of a p-variate normal distribution, provided the dimension p is greater than two. This paper extends the James-Stein estimator and highlights the benefits of applying these extensions to adaptive signal processing problems. The main contribution of this paper is the derivation of the James-Stein state filter (JSSF), which is a robust version of the Kalman filter. The JSSF is designed for situations where the parameters of the state-space evolution model are not known with any certainty. In deriving the JSSF, we derive several other results. We first derive a James-Stein estimator for estimating the regression parameter in a linear regression. A recursive implementation, which we call the James-Stein recursive least squares (JS-RLS) algorithm, is derived. The resulting estimate, although biased, has a smaller mean-square error than the traditional RLS algorithm. Finally, several heuristic algorithms are presented, including a James-Stein version of the Yule-Walker equations for AR parameter estimation.
<title>Design and development of a conformal load-bearing smart skin antenna: overview of the AFRL Smart Skin Structures Technology Demonstration (S<formula><sup><roman>3</roman></sup></formula>TD)</title> (1999)

Documented herein is a review of progress for the recently completed 'Smart Skin Structure Technology Demonstration' (S<SUP>3</SUP>TD) contract number F33615-93-C-3200 performed by Northrop Grumman Corporation, Hawthorne, California and TRW/ASD, Rancho Bernardo, San Diego, California under the Air Force Research Laboratory, Flight Dynamics Directorate, Structures Division's direction and sponsorship. S<SUP>3</SUP>TD was conceived as the first serious attempt, to made a complex antenna become a bone fide aircraft structural panel, without loss of overall structural integrity or electrical performance. The program successfully demonstrated the design, fabrication, and structural validation of a load bearing multifunction antenna component panel subjected to realistic aircraft flight load conditions. The final demonstration article was a structurally effective 36 by 36 inch curved multifunction antenna component panel that withstood running loads of 4,000 pounds per inch, and principal strain levels of 4,700 microstrain. Testing the structural component to ultimate, the panel failed at the predicted limit of 148 kips equating to 150 percent design limit load, after successfully completing one lifetime of fatigue. The load conditions were representative of a mid-fuselage F-18 class fighter component panel installation. The panel was designed not to buckle at ultimate failure, and the dominant failure mode was face sheet pull off, as predicted. Structural test data correlated closely with analysis. Wide band electrical performance for the component antenna panel was validated using anechoic chamber measurements and near field probing techniques, covering avionics communication navigation and identification and electronic warfare functions in the 0.15 to 2.2 GHz frequency regimes.
Role of Plasmapheresis in Hemolysis, Elevated Liver Enzymes and Low Platelets (HELLP) Syndrome (2023)

Hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome is a rare abnormality comprising a series of symptoms that make up a syndrome. It usually happens during pregnancy or right after delivery. We describe a case of a 31-year-old female G4P2A2 (Gravida 4 Para 2 Abortions 2) who presented to the hospital for normal vaginal delivery but immediately postpartum developed HELLP syndrome. Acute fatty liver of pregnancy was a differential that the patient also met the criteria for. Her condition improved after starting her on plasmapheresis without considering hepatic transplantation. We emphasize distinguishing the overlap of symptoms between HELLP syndrome vs. acute fatty liver of pregnancy and the outcomes of plasmapheresis in managing HELLP syndrome without needing hepatic transplantation.
The association of polymorphisms in hormone metabolism pathway genes, menopausal hormone therapy, and breast cancer risk: a nested case-control study in the California Teachers Study cohort (2011)

We found evidence that genetic variation in SLCO1B1 is associated with breast cancer risk in postmenopausal women, particularly among those using EPT.
HPF+ investigations with crash-simulation kernels (2002)

This paper reports on the use of HPF language extensions for the irregular computational and communications requirements arising in the algorithms found in crashworthiness simulation codes. The HPF language extensions, forming the HPF+ language definition, have been designed to deal with the requirements of complex, scientific applications which involve irregular constructs (from meshes to data structures and access patterns). The HPF+ language development is the central result of the HPF+ project (funded by the European Commission's ESPRIT Programme in the area of long Term Research).
Changes in human immunodeficiency virus type 1 virus load during mobilization and harvesting of hemopoietic progenitor cells (2000)

Genetic modification of hemopoietic progenitor cells ex vivo, followed by the infusion of the genetically modified cells into the human immunodeficiency virus-1 (HIV-1) infected donor, has been proposed as a treatment for HIV-1 infection. The current study was undertaken to evaluate the effect of hemopoietic stem cell mobilization and harvesting on HIV-1 replication in persons with HIV-1 infection. Eighteen HIV-1–infected persons received recombinant granulocyte colony-stimulating factor (G-CSF; Filgrastim) 10 μg/kg per day, for 7 days. On days 4 and 5, peripheral blood mononuclear cells were harvested by leukapheresis. The CD4+ lymphocyte count at entry was &gt;500/μL for 6 subjects, 200 to 500/μL for 6 subjects, and &lt;200/μL for 6 subjects. For 9 of 18 subjects, plasma HIV-1 RNA levels increased 4- to 100-fold (&gt;0.6 log10) above baseline between days 4 and 7 and returned to baseline by day 27. Significant increases of plasma HIV-1 RNA levels occurred in 5 subjects despite 3-drug antiretroviral therapy. Changes in CD4+ and CD34+ cells during mobilization and harvesting were similar in all subjects whether they had or did not have increased plasma HIV-1 RNA levels. Thus, mobilization and harvesting of bone marrow progenitor cells from persons infected with HIV-1 induced a transient increase in viral replication in some patients but was not associated with adverse effects. (Blood. 2000;95: 48-55)
Microfabricated silicon carbide thermionic energy converter for solar electricity generation (2012)

This paper reports an initial prototype for microfabricated silicon carbide (SiC) thermionic energy converters (TECs), which have promise as topping stages for solar thermal electricity generation. Our initial TEC device achieved cathode temperatures of over 2000 K with incident optical intensity of approximately 1 W/mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> (equivalent to 1000 Suns), remained structurally stable under thermal cycling, and maintained a temperature difference between the cathode and the anode of over 1000 K. In addition, our device converted the estimated 0.1 W of optical power incident on the cathode to 0.12 nW of electrical power. The low conversion efficiency is due to the high work function of SiC, which severely limits the thermionic current. According to the Richardson-Dushman equation, the thermionic current should increase by more than six orders of magnitude if we cesiate both electrodes of the converter, increasing the efficiency accordingly. In our initial experiments, the thermionic current was enhanced by ~1.5 orders of magnitude using the cesium coating.
A BIO-INSPIRED VISUAL FEEDBACK LOCOMOTION CONTROL BASED ON CNN UNIVERSAL MACHINE (2003)

In this paper a new framework for bio-inspired robot locomotion control, entirely based on Cellular Neural Networks (CNNs), is introduced. In fact, CNNs are employed both for generating locomotion patterns in a hexapod robot, and for its trajectory control via visual feedback. In the paper the latter problem will be emphasized, being the CNN locomotion generation problem already treated in literature. Feedback signals are images captured by a camera and processed in real time by a CNN used as analog image processor. The actual framework makes use of a traditional PC where a tool for the synchronization of the visual CNN chip and the robot control has been designed. This paper describes the methodology as an important stage for the study, definition and optimization of the overall control methodology. The results obtained reveal true real time capabilities and the PC interface can be easily substituted with a processing board to be integrated with the visual CNN and with the locomotion-devoted CNN, in order to constitute a unified integrated system for real time visual motion control in complex structures.
Recognition and representation of parallel processable streams in computer programs-II (Task/process Parallelism) (1969)

Advances in the areas of hardware technology, processor organization and programming science have given fresh impetus to research in parallel processing within single job streams. Given a program with a large degree of inherent parallelism, the theoretical time required for problem solution can be reduced “by a factor at least as great as the number of processors” [1].A need exists for new techniques for detecting parallel processable segments in sequentially coded programs and for indicating (representing) parallelism during actual program writing and coding. In a companion paper [4], the authors considered some methods of detecting and representing parallel processable “subtasks” within a task (process). In this paper we shall study the techniques of recognizing and representing parallel processable tasks within a single job stream (program).
Modifications to the electrical properties of PbTe by low-energy ion bombardment—interpretation in terms of differential sputtering and atomic mixing (1983)

Investigations are reported into the effect of 350 eV He+, Ar+ and Xe+ bombardment of PbTe. The studies were made on surfaces of thin films prepared by molecular beam deposition under UHV conditions. The modifications to the films were monitored by measurements of the films’ carrier transport properties. Bombardment-induced areal densities of carriers (electrons) up to 6×1013 cm−2 with near-bulk mobilities were observed for ion fluences up 1016 ions/cm2. The results are discussed in terms of preferential sputtering of Te in combination with beam-induced mixing. It is concluded that the induced damage is located very close to the film surface. Whereas in the case of Ar+ and Xe+ bombardment the altered layer appears to extend over a depth commensurate with the ion range, the results for He+ bombardment suggest that only the very surface is depleted of Te. There is evidence that ion-induced desorption of weakly bound surface species contributes significantly to the observed changes in the areal density of carriers.
The impact of a wireless audio system on communication in robotic-assisted laparoscopic surgery: A prospective controlled trial (2020)

The use of wireless headset devices improved quality of communication between team members and reduced the peak noise level in the robotic OR.
Integrated predicated and speculative execution in the IMPACT EPIC architecture (1998)

Explicitly Parallel Instruction Computing (EPIC) architectures require the compiler to express program instruction level parallelism directly to the hardware. EPIC techniques which enable the compiler to represent control speculation, data dependence speculation, and predication have individually been shown to be very effective. However, these techniques have not been studied in combination with each other. This paper presents the IMPACT EPIC Architecture to address the issues involved in designing processors based on these EPIC concepts. In particular, we focus on new execution and recovery models in which microarchitectural support for predicated execution is also used to enable efficient recovery from exceptions caused by speculatively executed instructions. This paper demonstrates that a coherent framework to integrate the three techniques can be elegantly designed to achieve much better performance than each individual technique could alone provide.
Three-dimensional hydrodynamic focusing in two-layer polydimethylsiloxane (PDMS) microchannels (2007)

In this work, we designed and fabricated a three-dimensional hydrodynamic focusing microfluidic device. The device comprises a two-layer PDMS microchannel structure. There are four inlet ports and one outlet port. The fluids are all injected by syringe pumps. A sample flow stream was first vertically constrained into a narrow stream, and then horizontally focused on one small core region from a cross-section perspective, which is useful for cell/particle counting. We showed the numerical and experimental images of the focused stream shape from a cross-section perspective; experimental images were captured using a confocal fluorescence microscope. We also investigated the effect of channel aspect ratio on the vertical focusing effect using CFD simulations. The results showed that the sample flow can be focused successfully in the lower aspect ratio of the main channel (slightly greater than 0.5) in our design. Furthermore, the effect of the Reynolds number on the vertical focusing effect was also investigated. The numerical results showed that the rectangular-like shape of the focused stream from the cross-section perspective was deformed as the Reynolds number was high due to stronger secondary flows produced in the vertical focusing unit. This phenomenon was also demonstrated experimentally. The device only works well at low Reynolds numbers (approximately less than 5). The device can be integrated into an on-chip flow cytometer.