gebhart/patrepeval huggingface dataset:
Inverse Scattering Homogenization method for conformal metamaterial structures (2015)

The composite nature of metamaterial structures, made up of metallic and dielectric parts, repeated and modulated in a certain order in the space, increases the numerical complexity of electromagnetic analysis: homogenizing such structures with a continuous dielectric model that achieves the same global electromagnetic response could be challenging, but it could give more information about the physical mechanism of wave propagation through it. The idea developed in this paper is to associate an equivalent permittivity to a novel metamaterial architecture (i.e. the microstrip-line-based metamaterial), solving an Inverse Scattering Problem (ISP). The expected global electromagnetic response involves the cloaking effect, artificially created by the radiation of surface waves propagating around the periodic structure. In the proposed Inverse Scattering Homogenization method (ISHM), the equivalent permittivity results exhibit values between zero and one, further tested in a Forward Scattering Problem (FSP), in order to establish a one-to-one correspondance between heterogeneous (physical) and homogeneous (mathematical) model.
Orthogonal functions based integral inequalities and their applications to time delay systems (2016)

This paper presents a generalization of the recent proposed Bessel-Legendre inequality, which is specifically derived for analyzing linear time delay systems. The proposed inequalities are able to handle almost all type of classical orthogonal polynomials such as Jacobi, Laguerre and Hermite. In utilizing Jacobi polynomials, numerous existing results can be treated as the special cases of the proposed inequalities. Furthermore, we show that it is possible to apply these inequalities simultaneously to derive lower bounds for Krasovskii functionals, thus less conservative results can be obtained. Finally, the resulting inequalities have been briefly extended to handle the systems with fast time varying delays. Two numerical examples are presented to demonstrate the effectiveness of the proposed inequalities.
Stay home, stay safe? (2022)

Stay home, stay safe? Pandemic-specific effects on domestic violence advices in the Netherlands There have been worldwide concerns that the COVID-19 restrictions have led to an increase in domestic violence. In this study the authors examine the domestic violence advices that have been registered by all 26 Veilig Thuis ( Safe Home ) regions in the Netherlands. To study potential differences in prevalence, suspected nature and the type of person that seeks advice on domestic violence prior and during the COVID-19 pandemic, the authors compare data from 2019 with 2020 and 2021. The findings show a general increase in advices in 2020 and 2021, that cannot be unambiguously attributed to the COVID-19 restrictions.
Werkzeuge für das Wissenmanagement (2002)

Wissensmanagement ist nicht gleichbedeutend mit Software ? aber es kann verbessert und erm?glicht werden, wenn Technologien sinnvoll eingesetzt werden. In dieser kurzen ?bersicht ?ber Werkzeuge f?r das Wissensmanagement werden wir Ankn?pfungspunkte f?r einen sinnvollen Einsatz von Informations- und Kommunikationstechnologien (IKT) aufzeigen. Dabei gehen wir auf die folgenden Einsatzm?glichkeiten ein: Wissensarbeit optimieren, Wissenstr?ger vernetzen, Wissenssammlungen organisieren, Wissenserwerb unterst?tzen, Wissensentwicklung verbessern und Wissensschutz gew?hrleisten. F?r die meisten Zwecke sind IKT-Werkzeuge f?r das Wissensmanagement jedoch an eine Weiterentwicklung der organisatorischen Wissensmanagementkompetenzen gekoppelt. Stichworte: Wissensmanagement, ?bersicht der Werkzeuge, Einsatz von Informations- und Kommunikationstechnologien (IKT), Wissensportale, Kooperationssysteme, Vernetzung von Wissenstr?gern, Organisation von Wissenssammlungen, Entwicklung von Wissen, Wissensschutz
Development of a robotic surgical assistant (2002)

After development of a passive articulated localization arm we are now developing a robotic surgical assistant for neurosurgery. Our study includes ergonomic, precision and safety aspects. As a result of early work interactive hand and computer driven use might be developed. Mechatronic approach is supposed to minimize system's weight, friction and inertia of mass for user. The goal of this work, interests and preliminary results are presented.
A phase I single-dose trial of gadolinium texaphyrin (Gd-Tex), a tumor selective radiation sensitizer detectable by magnetic resonance imaging. (1999)

Gadolinium Texaphyrin (Gd-Tex) is a radiation sensitizer with a novel mechanism of action that sensitizes both oxic and hypoxic cells, localizes selectively in tumors, and is detectable by magnetic resonance imaging (MRI). This Phase I single-dose trial of Gd-Tex administered concurrently with radiation therapy was carried out to determine the maximally tolerated dose (MTD), dose-limiting toxicities, pharmacokinetics, and biolocalization of Gd-Tex as determined by MRI. Adults with incurable cancers of any histology requiring radiation therapy were eligible. A single i.v. dose of Gd-Tex was followed at least 2 h later by radiation therapy. The Gd-Tex dose was escalated in cohorts of 3 to 5 patients. Thirty-eight patients (median age, 58 years; range, 35-77 years) with incurable cancers of the lung (26), cervix (3), or other solid tumors (9) received a total of 41 single administrations of Gd-Tex. The Gd-Tex dose was escalated from 0.6 to 29.6 mg/kg. Irradiated sites included the thorax, brain, pelvis, bone, soft tissue, and sites of nodal metastases. The MTD was 22.3 mg/kg, determined by reversible acute tubular necrosis as the dose-limiting toxicities. Gd-Tex selectively accumulated in primary and metastatic tumors as demonstrated by MRI. No increase in radiation toxicity to normal tissues was seen. The median half-life of Gd-Tex after single-dose administration is 7.4 h. This study demonstrates that Gd-Tex is well tolerated in doses below the MTD, and that there is selective biolocalization in tumors. The maximum recommended dose for single administrations is 16.7 mg/kg.
Building Anatomically Realistic Jaw Kinematics Model from Data (2018)

This paper considers a different aspect of anatomical face modeling: kinematic modeling of the jaw, i.e., the Temporo-Mandibular Joint (TMJ). Previous work often relies on simple models of jaw kinematics, even though the actual physiological behavior of the TMJ is quite complex, allowing not only for mouth opening, but also for some amount of sideways (lateral) and front-to-back (protrusion) motions. Fortuitously, the TMJ is the only joint whose kinematics can be accurately measured with optical methods, because the bones of the lower and upper jaw are rigidly connected to the lower and upper teeth. We construct a person-specific jaw kinematic model by asking an actor to exercise the entire range of motion of the jaw while keeping the lips open so that the teeth are at least partially visible. This performance is recorded with three calibrated cameras. We obtain highly accurate 3D models of the teeth with a standard dental scanner and use these models to reconstruct the rigid body trajectories of the teeth from the videos (markerless tracking). The relative rigid transformations samples between the lower and upper teeth are mapped to the Lie algebra of rigid body motions in order to linearize the rotational motion. Our main contribution is to fit these samples with a three-dimensional nonlinear model parameterizing the entire range of motion of the TMJ. We show that standard Principal Component Analysis (PCA) fails to capture the nonlinear trajectories of the moving mandible. However, we found these nonlinearities can be captured with a special modification of autoencoder neural networks known as Nonlinear PCA. By mapping back to the Lie group of rigid transformations, we obtain parameterization of the jaw kinematics which provides an intuitive interface allowing the animators to explore realistic jaw motions in a user-friendly way.
Blood-brain barrier protein recognized by monoclonal antibody. (1987)

An IgG1 mouse monoclonal antibody produced in response to immunization with rat brain homogenate reacted with endothelial cells in the central and peripheral nervous system. Because antibody reactivity was associated with endothelia that have a selective permeability barrier, the antibody was called anti-endothelial-barrier antigen (anti-EBA). Paraffin sections of Bouins'-fixed rat tissue were used for initial screening and subsequent characterization of antibody reactivity. The antibody was generally unreactive with endothelial cells in other organs and with nonendothelial cells in or outside of the nervous system. Antibody binding was greatly reduced or absent in endothelia of the area postrema and choroid plexus, sites known to possess fenestrated blood vessels. In developing rat brain, anti-EBA binding to some microvessels was seen at 3 days postnatally. Anti-EBA reactivity outside the nervous system occurred in spleen and skin. Patchy reaction with portions of some spleen blood vessels and binding to some cells in the spleen were observed. In the skin, small cells, tentatively identified as Langerhans cells, which participate in Ia presentation, were stained. On immunoblots of rat brain microvessel preparations electrophoresed in Na-DodSO4/polyacrylamide gels, anti-EBA reacted with a protein triplet of Mr 30,000, 25,000, and 23,500 components.
Esquizofrenia refratária (2007)

Refractory schizophrenia affects at least one third of patients with schizophrenia and the best evidence shows that is monotherapy with clozapine remains the mainstay for the treatment of such condition. Antipsychotic polipharmacy is not supported by current evidence and recent clinical trials have shown that clozapine augmentation with antipsychotics has no benefit over placebo.
Integration challenges for terabit class mid board photonic transceivers (2016)

In this short paper we are describing three key challenges to be addressed in designing the next generation of Mid Board Optical Modules using Silicon Photonics technology: single mode fiber coupling, photonic circuit design in a dedicated environment (PDK), and laser integration using mass fabrication compatible techniques. These three challenges are illustrated with some related achievements.
Square Wave Voltammetric Determination of 8-Hydroxyquinoline-2-Carboxaldehyde Isonicotinoyl Hydrazone (INHHQ), a Promising Metal-Protein Attenuating Compound for the Treatment of Alzheimer’s Disease, Using a Multiwalled Carbon Nanotube (MWCNT) Modified Glassy Carbon Electrode (GCE) (2020)

An analytical method for the determination of 8-hydroxyquinoline-2-carboxaldehyde isonicotinoyl hydrazone (INHHQ) is reported for the first time. The electrochemical method involving INHHQ was performed at a glassy carbon (GC) electrode modified with multiwalled carbon nanotubes (MWCNTs). The GC-MWCNTs promoted a significantly large enhancement in the Faradaic current employing square wave voltammetry (SWV) to determine INHHQ in the fortified extracts of the brain from Wistar rats. In addition, the MWCNTs increased the active electrode area, produced an electro-catalytic effect and provided significantly faster electron transfer. The quantification of INHHQ was made by the use of a supporting electrolyte consisting of Britton-Robinson (BR) buffer at a concentration of 0.02 mol L−1 and a pH of 11.0 in 0.25 mol L−1 KCl. The quantitative assay using square wave voltammetry was achieved by the serial addition of a standard into the electrochemical cell containing the sample. The limit of detection (LOD) for the protocol was equal to 0.25 µg mL−1 (0.85 µmol L−1). A procedure involving thin-layer chromatography (TLC) was employed in order to improve the selectivity required to determine INHHQ. The recoveries of the analyte in brain tissue from Wistar rats were statistically comparable to the values obtained by a high-performance liquid chromatography (HPLC) protocol.
Real time tracking in liver SBRT: comparison of CyberKnife and Vero by planning structure-basedγ-evaluation and dose-area-histograms (2016)

The purpose of this study was to evaluate and compare two clinical tracking systems for radiosurgery with regard to their dosimetric and geometrical accuracy in liver SBRT: the robot-based CyberKnife and the gimbal-based Vero. Both systems perform real-time tumour tracking by correlating internal tumour and external surrogate motion. CyberKnife treatment plans were delivered to a high resolution 2D detector array mounted on a 4D motion platform, with the platform simulating (a) tumour motion trajectories extracted from the corresponding CyberKnife predictor log files and (b) the tumour motion trajectories with superimposed baseline-drift. Static reference and tracked dose measurements were compared and dosimetric as well as geometrical uncertainties analyzed by a planning structure-based evaluation. For (a), γ-passing rates inside the CTV (γ-criteria of 1% / 1 mm) ranged from 95% to 100% (CyberKnife) and 98% to 100% (Vero). However, dosimetric accuracy decreases in the presence of the baseline-drift. γ-passing rates for (b) ranged from 26% to 92% and 94% to 99%, respectively; i.e. the effect was more pronounced for CyberKnife. In contrast, the Vero system led to maximum dose deviations in the OAR between +1.5 Gy to +6.0 Gy (CyberKnife: +0.5 Gy to +3.5 Gy). Potential dose shifts were interpreted as motion-induced geometrical tracking errors. Maximum observed shift ranges were -1.0 mm to +0.7 mm (lateral) /-0.6 mm to +0.1 mm (superior-inferior) for CyberKnife and -0.8 mm to +0.2 mm /-0.8 mm to +0.4 mm for Vero. These values illustrate that CyberKnife and Vero provide high precision tracking of regular breathing patterns. Even for the modified motion trajectory, the obtained dose distributions appear to be clinical acceptable with regard to literature QA γ-criteria of 3% / 3 mm.
Stress-mediated exit to quiescence restricted by increasing persistence in CDK4/6 activation (2020)

Mammalian cells typically start the cell-cycle entry program by activating cyclin-dependent protein kinase 4/6 (CDK4/6). CDK4/6 activity is clinically relevant as mutations, deletions, and amplifications that increase CDK4/6 activity contribute to the progression of many cancers. However, when CDK4/6 is activated relative to CDK2 remained incompletely understood. Here, we developed a reporter system to simultaneously monitor CDK4/6 and CDK2 activities in single cells and found that CDK4/6 activity increases rapidly before CDK2 activity gradually increases, and that CDK4/6 activity can be active after mitosis or inactive for variable time periods. Markedly, stress signals in G1 can rapidly inactivate CDK4/6 to return cells to quiescence but with reduced probability as cells approach S phase. Together, our study reveals a regulation of G1 length by temporary inactivation of CDK4/6 activity after mitosis, and a progressively increasing persistence in CDK4/6 activity that restricts cells from returning to quiescence as cells approach S phase.
Management of Late-Onset Tibia Vara in the Obese Patient by Using Circular External Fixation (1997)

Previously published series of surgery for late-onset tibia vara reported a significant number of complications and fair or poor results. Obesity in many of these patients makes surgical intervention an even more daunting prospect. Circular external fixation is applicable to almost any limb size and allows weight bearing as tolerated, with gradual adjustment of alignment. Twenty-five tibiae in 17 patients who exceeded their ideal body weight by > or =50% underwent correction of late-onset tibia vara with the Ilizarov technique. Average age at surgery was 11 years 7 months (range, 7 years 8 months to 15 years 11 months). Mean varus deformity was 27 degrees (range, 10-55 degrees). Treatment time averaged 12 weeks in patients without lengthening and 16.9 weeks in those requiring lengthening (mean, 3.5 cm). All patients achieved alignment within 5 degrees of normal. Complications included one delayed union, premature consolidation in one, and two residual limb-length inequalities. There were no cases of osteomyelitis, compartment syndrome, or nerve palsy. These results are a significant improvement over reports of traditional methods in these difficult patients.
Production of dimethyl telluride and elemental tellurium by bacteria amended with tellurite or tellurate (2001)

Abstract The purpose of this study was to determine whether a facultative anaerobe, Pseudomonas fluorescens K27, would produce dimethyl telluride when anaerobic cultures were amended with differing concentrations of sodium tellurate and/or sodium tellurite and how that volatile organotellurium production varied over time. Batch bacterial bioreactor experiments were undertaken in order to observe the changes in the headspace of a growth medium solution inoculated with P. fluorescens and amended with tellurium salts. Gas samples were taken from the bioreactor every hour and were analyzed by capillary gas chromatography using fluorine‐induced chemiluminescence detection to determine compounds in the headspace. Liquid samples were analyzed by spectrophotometer to determine optical densities, which were used as an indicator of cell growth. Verification of the identity of the dimethyl telluride produced in the bacterial headspace above a tellurate‐amended culture was achieved by comparison with the chromatographic retention time of an authentic (CH 3 ) 2 Te standard and by gas chromatography/mass spectrometry. The time course production of dimethyl telluride varied with amendment salts' tellurium oxidation states and concentrations. Increasing tellurate concentrations caused slower bacterial growth, but those cultures reached the stationary phase sooner than cultures amended with tellurite concentrations 10 or 100 times less. Black elemental tellurium (Te 0 ) was produced by live cultures amended with tellurium salts but not by sterile controls. The amount of tellurium in the solid phase (as Te 0 and in/or on cells) harvested from replicate, anaerobic cultures of P. fluorescens sampled after 92 h of incubation was approximately 34%. Mixed tellurite/tellurate amendment experiments exhibited a synergistic toxic effect and yielded less final biomass and very little dimethyl telluride production compared with cultures amended with either tellurate or tellurite alone. Copyright © 2001 John Wiley &amp; Sons, Ltd.
Density measurements for the National Ignition Facility (NIF) opacity platform (2022)

The Opacity Platform on the National Ignition Facility (NIF) has been developed to measure opacities at varying densities and temperatures relevant to the solar interior and thermal cooling rates in white dwarf stars. The typical temperatures reached at NIF range between 150 and 210 eV, which allow these measurements to be performed experimentally. The captured opacities are crucial to validating radiation-hydrodynamic models that are used in astrophysics. The NIF opacity platform has a unique new capability that allows in situ measurement of the sample expansion. The sample expansion data are used to better understand the plasma conditions in our experiments by inferring the sample density throughout the duration of the laser drive. We present the details of the density measurement technique, data analysis, and recent results for Fe and MgO.
Generating useful network-based features for analyzing social networks (2008)

Recently, many Web services such as social networking services, blogs, and collaborative tagging have become widely popular. Many attempts are being made to investigate user interactions by analyzing social networks among users. However, analyzing a social network with attributional data is often not an easy task because numerous ways exist to define features through aggregation of different tables. In this study, we propose an algorithm to identify important network-based features systematically from a given social network to analyze user behavior efficiently and to expand the services. We apply our method for link-based classification and link prediction tasks with two different datasets, i.e., an @cosme (an online viral marketing site) dataset and a Hatena Bookmark (collaborative tagging service) dataset, to demonstrate the usefulness of our algorithm. Our algorithm is general and can provide useful network-based features for social network analyses.
Quantum simulations of one dimensional quantum systems (2015)

We present quantum algorithms for the simulation of quantum systems in one spatial dimension, which result in quantum speedups that range from superpolynomial to polynomial. We first describe a method to simulate the evolution of the quantum harmonic oscillator (QHO) based on a refined analysis of the Trotter-Suzuki formula that exploits the Lie algebra structure. For total evolution time $t$ and precision $ε&gt;0$, the complexity of our method is $ O(\exp(γ\sqrt{\log(N/ε)}))$, where $γ&gt;0$ is a constant and $N$ is the quantum number associated with an "energy cutoff" of the initial state. Remarkably, this complexity is subpolynomial in $N/ε$. We also provide a method to prepare discrete versions of the eigenstates of the QHO of complexity polynomial in $\log(N)/ε$, where $N$ is the dimension or number of points in the discretization. This method may be of independent interest as it provides a way to prepare, e.g., quantum states with Gaussian-like amplitudes. Next, we consider a system with a quartic potential. Our numerical simulations suggest a method for simulating the evolution of sublinear complexity $\tilde O(N^{1/3+o(1)})$, for constant $t$ and $ε$. We also analyze complex one-dimensional systems and prove a complexity bound $\tilde O(N)$, under fairly general assumptions. Our quantum algorithms may find applications in other problems. As an example, we discuss the fractional Fourier transform, a generalization of the Fourier transform that is useful for signal analysis and can be formulated in terms of the evolution of the QHO.
A comprehensive design approach for a three-phase high-frequency single-switch discontinuous-mode boost power factor corrector based on analytically derived normalized converter component ratings (1995)

In this paper the peak, mean, and RMS values of the component currents of a three-phase single-switch discontinuous inductor current mode boost rectifier are calculated analytically. The values are given in rated form in dependency on the output power and on the ratio of output voltage to the amplitude of the mains voltage. Furthermore, the influence of the voltage transfer ratio on the shape of the mains currents and on the power factor of the system is analyzed. The theoretical analysis is verified by digital simulation and a good consistency is achieved. Finally, the approach of the converter dimensioning based on the graphical representation of the calculation results is described and illustrated using a specific example. The correctness of the dimensioning is verified by measurements on a laboratory model.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Chapitre 22. Recherche de la plante hôte à distance (2013)

Ce chapitre traite des comportements de recherche à distance de la plante hôte par les insectes en vue de l’établissement de tout ou partie du cycle reproducteur, mais aussi de plantes utilisées comme ressources temporaires (recherche de nutriments spécifiques ou de molécules de défense par exemple). La localisation de la plante à distance et la mise en œuvre des comportements de recherche sont des étapes essentielles à la rencontre entre le consommateur (insecte) et sa ressource, mais aussi ...