gebhart/patrepeval huggingface dataset:
Role of the RecBCD Recombination Pathway in Salmonella Virulence (2002)

Mutants of Salmonella enterica lacking the RecBC function are avirulent in mice and unable to grow inside macrophages (N. A. Buchmeier, C. J. Lipps, M. Y. H. So, and F. Heffron, Mol. Microbiol. 7:933-936, 1993). The virulence-related defects of RecBC(-) mutants are not suppressed by sbcB and sbcCD mutations, indicating that activation of the RecF recombination pathway cannot replace the virulence-related function(s) of RecBCD. Functions of the RecF pathway such as RecJ and RecF are not required for virulence. Since the RecBCD pathway, but not the RecF pathway, is known to participate in the repair of double-strand breaks produced during DNA replication, we propose that systemic infection by S. enterica may require RecBCD-mediated recombinational repair to prime DNA replication inside phagocytes. Mutants lacking both RecD and RecJ are also attenuated in mice and are unable to proliferate in macrophages, suggesting that exonucleases V and IX provide alternative functions for RecBCD-mediated recombinational repair during Salmonella infection.
Life Changes and Myocardial Infarction (1976)

Although statistically significant, the relation between certain life changes and imminent myocardial infarction appears to be quantitatively weak. Of particular importance are events connected with employment. However, the summation of life changes has not proved to be of use in the prediction of imminent myocardial infarction. For patients with ischemic heart disease, variations in life change measures have proved to be of use in the prediction of changes in catecholamine output and in prognosis. When genetic factors are held constant, as in monozygotic twin pairs vulnerable to ischemic heart disease, more life changes in one partner may indicate a greater risk of unexpected sudden cardiac death in this partner than in the other twin. The self-rating of the severity of each experienced event has proved more useful than "standard weights" in the retrospective discrimination of myocardial infarction patients. Further clinical and epidemiological studies are needed in this field. For the future, the following recommendations are made: The studies should be prospective. The individual's habitual level and actual level of the change should be recorded. The severity of events should be self-rated. Risk variables, known to be of importance to the development of MI should be recorded. They are for instance smoking habits, blood pressure, serum lipids and genetic predisposition. Psychological variables should be mentioned separately in this connection.
PHONIX: The algorithm (1990)

PHONIX is a phonetic retrieval technique developed for use with the URICA library system. It has been successfully installed at a number of URICA sites in Southern Africa. PHONIX has been found to be particularly useful when applied to personal names, specifically author surnames in the context of a library system. Certain names such as Anton Chekov have been variously transliterated as TSJECHOF, TSJECHOW, TJEKHOW, CHEKHOV, CHEKHOW etc., in the multi‐lingual environment of libraries in Southern Africa. PHONIX complements the more conventional information retrieval techniques used by URICA, and the algorithm used is explained as a simple, easy to apply, set of rules. This contribution follows on from a previous paper.
Multidimensional Separations (2014)

ADVERTISEMENT RETURN TO ISSUEEditorialNEXTMultidimensional SeparationsDaniel W. Armstrong† and Staci L. Massey Simonich‡View Author Information† Department of Chemistry and Biochemistry, University of Texas at Arlington, Arlington, Texas 76019, United States‡ Department of Environmental and Molecular Toxicology and Department of Chemistry, Oregon State University, Corvallis, Oregon 97331, United StatesCite this: Anal. Chem. 2014, 86, 23, 11473Publication Date (Web):November 3, 2014Publication History Published online3 November 2014Published inissue 2 December 2014https://pubs.acs.org/doi/10.1021/ac503953mhttps://doi.org/10.1021/ac503953meditorialACS PublicationsCopyright © 2014 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views1345Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (118 KB) Get e-AlertscloseSUBJECTS:Chromatography,Software Get e-Alerts
Kinetics and Thermochemistry of the Reaction of 1-Chloroethyl Radical with Molecular Oxygen (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTKinetics and Thermochemistry of the Reaction of 1-Chloroethyl Radical with Molecular OxygenVadim D. Knyazev, Akos Bencsura, Ilia A. Dubinsky, David Gutman, Carl F. Melius, and Selim M. SenkanCite this: J. Phys. Chem. 1995, 99, 1, 230–238Publication Date (Print):January 1, 1995Publication History Published online1 May 2002Published inissue 1 January 1995https://pubs.acs.org/doi/10.1021/j100001a036https://doi.org/10.1021/j100001a036research-articleACS PublicationsRequest reuse permissionsArticle Views84Altmetric-Citations25LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Constructing Cube Blocks Effectively for Stream Data Analysis (2006)

With the rapid growth of WWW, many applications based on web are generating tremendous amount of data. Analyzing and mining such data will be important for administrators and other users. Because these data are increasing continuously and rapidly, retrieving these data efficiently and effectively are challenging tasks. In this paper, we propose a new Cube Block model to organize multi-dimensional data efficiently for online analysis and mining. The main idea of Cube Block model is to split the whole data set into blocks by dividing time into exponential time frames. In each block, we omit individual time identifiers of data items and aggregate duplicate data items to one data cell. Cube Block model uses the approximating method to get historical data in any time interval. The approximation accuracy is guaranteed by an upper bound and a lower bound. For the implementation of Cube Block model, we develop the CB-Builder system to scan data and construct cube blocks. CB-Builder's algorithm complexity (runtime and space cost) is analyzed in this paper. Experiments on synthetic data sets demonstrate that Cube Block model with its implementation CB-Builder is an effective and efficient tool for web application data analysis and mining.
Transition into adulthood: Tuberous sclerosis complex, Sturge‐Weber syndrome, and Rasmussen encephalitis (2014)

Children with tuberous sclerosis complex, Sturge-Weber syndrome, and Rasmussen encephalitis all have complex but differing needs in the process of transition/transfer to adult care. All three may be associated with long-term normal intelligence or a varying degree of intellectual disability. In tuberous sclerosis complex, the emphasis of care in adulthood shifts from seizure control and developmental issues to renal and psychiatric disease and other issues. In Sturge-Weber syndrome, the emphasis shifts from seizure control and rehabilitation to management of disability and migraine. In Rasmussen encephalitis, transition may be particularly complex for those with adolescent onset. Those successfully operated on for childhood onset have a static problem and the potential to do well in life.
Dynamics of muscle fibre growth during postnatal mouse development (2010)

Postnatal fast muscle fibre type growth is divided into distinct phases in mouse EDL: myofibre hypertrophy is initially supported by a rapid increase in the number of myonuclei, but nuclear addition stops around P21. Since the significant myofibre hypertrophy from P21 to adulthood occurs without the net addition of new myonuclei, a considerable expansion of the myonuclear domain results. Satellite cell numbers are initially stable, but then decrease to reach the adult level by P21. Thus the adult number of both myonuclei and satellite cells is already established by three weeks of postnatal growth in mouse.
Dielectric relaxation in 0-3 PVDF-Ba(Fe1/2Nb1/2)O3 composites (2016)

(1-x)PVDF-xBa(Fe1/2Nb1/2)O3 ceramic-polymer composites with x = 0.025, 0.05, 0.10, 0.15 were prepared using melt-mixing technique. The crystal symmetry, space group and unit cell dimensions were determined from the XRD data of Ba(Fe1/2Nb1/2)O3 using FullProf software, whereas crystallite size and lattice strain were estimated using Williamson-Hall approach. The distribution of Ba(Fe1/2Nb1/2)O3 particles in the PVDF matrix were examined on the cryo-fractured surfaces using a scanning electron microscope. Cole-Cole and pseudo Cole-Cole analysis suggested the dielectric relaxation in this system to be of non-Debye type. Filler concentration dependent real and imaginary parts of dielectric constant as well as ac conductivity data followed definite trends of exponential growth types of variation.
Factors that Influence the Duration of the Staminate and Pistillate Phases of Lobelia cardinalis Flowers (1984)

Staminate duration in Lobelia cardinalis is significantly affected by the amount and frequency of pollen removal from the anther tube. Repeated pollen removal shortens the staminate phase, while limited or no pollen removal greatly increases this phase. Pistillate duration is decreased significantly by both pollination and an increase in the duration of the staminate phase. Both staminate duration and pistillate duration increase with flower position on inflorescences with no developing fruit but show no change in duration with position when developing fruits are present. Because the duration of both the staminate and pistillate phases in natural populations falls between the minimum and maximum duration in experimental plants, we conclude that the actual duration of the respective phases in natural populations is controlled by pollinator activity.
Approche probabiliste pour l'analyse des tolérances des produits hyperstatiques – application à une pompe (2015)

International audience
A multicenter randomized controlled study of an extracorporeal cytokine hemoadsorption device in septic patients (2013)

A novel sorbent hemoadsorption device for cytokine removal (CytoSorbents, USA) was developed and successfully tested in animal models of sepsis. The experience in the clinical setting is still limited to case reports. In this first clinical trial, we tested the hypothesis that treatment with sorbent hemoadsorption could safely and effectively reduce cytokines in septic patients with acute lung injury (ALI).
Logo detection in images using HOG and SIFT (2017)

In this paper we present a study of logo detection in images from a media agency. We compare two most widely used methods - HOG and SIFT on a challenging dataset of images arising from a printed press and news portals. Despite common opinion that SIFT method is superior, our results show that HOG method performs significantly better on our dataset. We augment the HOG method with image resizing and rotation to improve its performance even more. We found out that by using such approach it is possible to obtain good results with increased recall and reasonably decreased precision.
A metabolome-wide characterization of the diabetic phenotype in ZDF rats and its reversal by pioglitazone (2018)

Type 2 diabetes (T2D) is a complex metabolic disease associated with alterations in glucose, lipid and protein metabolism. In order to characterize the biochemical phenotype of the Zucker diabetic fatty (ZDF) rat, the most common animal model for the study of T2D, and the impact of the insulin sensitizer pioglitazone, a global, mass spectrometry-based analysis of the metabolome was conducted. Overall, 420 metabolites in serum, 443 in the liver and 603 in the intestine were identified at study end. In comparison to two control groups, obese diabetic ZDF rats showed characteristic metabolic signatures that included hyperglycemia, elevated β-oxidation, dyslipidemia-featured by an increase in saturated and monounsaturated fatty acids and a decrease of medium chain and of polyunsaturated fatty acids in serum-and decreased amino acid levels, consistent with their utilization in hepatic gluconeogenesis. A 13-week treatment with the PPARγ agonist pioglitazone reversed most of these signatures: Pioglitazone improved glycemic control and the fatty acid profile, elevated amino acid levels in the liver, but decreased branched chain amino acids in serum. The hitherto most comprehensive metabolic profiling study identified a biochemical blueprint for the ZDF diabetic model and captured the impact of genetic, nutritional and pharmacological perturbations. The in-depth characterization on the molecular level deepens the understanding and further validates the ZDF rat as a suitable preclinical model of diabetes in humans.
Fermionic Condensates (2005)

Ultracold atomic gases have proven to be remarkable model systems for exploring quantum mechanical phenomena. Experimental work on gases of fermionic atoms in particular has seen large recent progress including the attainment of so‐called fermionic condensates. In this article we will discuss this recent development and the unique control over interparticle interactions that made it possible.
Catalytic Asymmetric Mono‐Fluorination of α‐Keto Esters: Synthesis of Optically Active β‐Fluoro‐α‐Hydroxy and β‐Fluoro‐α‐Amino Acid Derivatives (2012)

Die enantioselektive Monofluorierung von α-Ketoestern gelang mithilfe eines mild basischen μ-Hydroxo-Palladiumkomplexes als Katalysator. Die anschließende Reduktion lieferte optisch aktive β-Fluor-α-hydroxyester, die in medizinisch relevante β-Fluor-α-aminoester überführt wurden. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
THE RTM-LIGHT MANUFACTURING PROCESS: EXPERIMENTATION AND MODELLING (2009)

An initial study was carried out to investigate key aspects of the RTM-Light process, in particular the effect of mould flexibility on process times, cavity thickness and pressure distributions. Radial and peripheral injection experiments have been performed, utilising mould platens of varied flexural stiffness. A simulation of these RTM-Light experiments was developed using an iterative coupling procedure to solve the fluid-mould interaction problem. Initial comparisons of experimental and numerical results are presented.
Widespread transcription of the growth hormone-releasing peptide receptor gene in neuroendocrine human tumors (1997)

GH-releasing peptides are a new class of potent GH secretagogs (GHS) in vivo and in vitro. In normal man GHS also elicit low but definite ACTH and prolactin secretion. Recently it was shown that patients with pituitary corticotrope adenomas respond to GHS with a dramatic rise in ACTH secretion, and it has been suggested that GHS may provide a diagnostic tool to differentiate Cushing's disease from the ectopic ACTH syndrome. GHS actions are mediated by a G protein-coupled receptor recently characterized and cloned in man and rat. In this study we analyzed GHS receptor (GHS-R) expression in various types of pituitary adenoma and in endocrine and non-endocrine lung tumors by RT-PCR. GHS-R transcription was detected in all normal pituitaries and GH-secreting adenomas as expected. The receptor was also transcribed in some prolactin-secreting adenomas and non-functioning adenomas, and, more strikingly, in all 18 ACTH-secreting pituitary adenomas studied. Furthermore, it was frequently expressed in endocrine bronchial tumors, especially carcinoids, whereas it was not found or barely detectable in non-endocrine bronchial tumors. Again ACTH-secreting carcinoids of the lung were all positive for GHS-R expression. These results show that GHS-R transcription is a common feature of endocrine tumors independent of their type and origin.
Achieving Universal Coverage without Turning to a Single Payer: Lessons from 3 Other Countries (2017)

A primary obstacle to achieving affordable universal coverage is the high costs of those with diseases or costly traumatic events — approximately 20% of patients account for approximately 80% of all health care spending. Although many OECD nations rely on a governmental single-payer model to achieve universal coverage, three other countries — Switzerland, Germany, and Singapore — use use private sector insurance to offer affordable universal coverage. We review potentially helpful lessons from these nations to inform American health policy.
InPRO: Automated Indoor Construction Progress Monitoring Using Unmanned Aerial Vehicles (2016)

In this research, an envisioned automated intelligent robotic solution for automated indoor data collection and inspection that employs a series of unmanned aerial vehicles (UAV), entitled â InPROâ , is presented. InPRO consists of four stages, namely: 1) automated path planning; 2) autonomous UAV-based indoor inspection; 3) automated computer vision-based assessment of progress; and, 4) automated updating of 4D building information models (BIM). The works presented in this thesis address the third stage of InPRO. A series of computer vision-based methods that automate the assessment of construction progress using images captured at indoor sites are introduced. The proposed methods employ computer vision and machine learning techniques to detect the components of under-construction indoor partitions. In particular, framing (studs), insulation, electrical outlets, and different states of drywall sheets (installing, plastering, and painting) are automatically detected using digital images. High accuracy rates, real-time performance, and operation without a priori information are indicators of the methodsâ promising performance.
Preface (2012)

Vigilance is the only tool we have to manage the errors that lurk around each hospital corridor. It is hoped that this book will not only help prepare for the challenges of the new MRCS exam, but also help keep our clinical vigilance honed and ready for the supreme challenge – our sick patients.
Magnetotransport behavior of Co nanowires coupled to Ni80Fe20 films (2010)

We have fabricated and characterized hybrid-trilayer ferromagnetic structures comprising of 60-nm-thick Ni80Fe20 (Py) film grown on top of patterned array of 60-nm-thick Co nanowires (NWs) with Cu spacer layer. The hybrid structures display unique magnetic and transport properties due to the nonuniform magnetization distribution from the Py layer inducing local stray fields, which could be coupled to the underlying Co NWs. The temperature dependence of the magnetoresistance behavior is dominated by the interplay between the anisotropic magnetoresistance and the giant magnetoresistance effects.
Phase retrieval with Fourier-weighted projections (2008)

In coherent lensless imaging, the presence of image sidelobes, which arise as a natural consequence of the finite nature of the detector array, was early recognized as a convergence issue for phase retrieval algorithms that rely on an object support constraint. To mitigate the problem of truncated far-field measurement, a controlled analytic continuation by means of an iterative transform algorithm with weighted projections is proposed and tested. This approach avoids the use of sidelobe reduction windows and achieves full-resolution reconstructions.
Immunohistochemical expression of vascular endothelial growth factor, matrix metalloproteinase 2, and matrix metalloproteinase 9 in cutaneous melanocytic lesions (2002)

On the basis of the current data showing that malignant melanocytic tumors displayed strong VEGF expression, whereas benign melanocytic proliferations showed no immunoreactivity for VEGF, VEGF also may be used as a discriminating factor to distinguish malignant melanoma from lesions of uncertain histology.
Distributing representation for robust interpretation of dialogue utterances (2000)

A syntax tree or standard semantic representation can be represented as a set of indexed constraints. This paper describes how this idea can be used in task oriented dialogue systems to provide interpretation rules which incorporate structural and contextual constraints where available, and degrade gracefully on ungrammatical input.
A non-cooperative long-range biometric image tracking and recognition (BITAR) method for maritime surveillance (2008)

To address the challenges on non-cooperative long-distance human authentication, identification, and verification; we propose an innovative scheme for developing a robust and automatic long-range biometric recognition system by combining face recognition and iris recognition of non-cooperative individuals in 24/7 operations. The system consists of three cameras. One is a wide field of view (WFOV) CCD video camera with InfraRed (IR) filter and powerful IR illuminators for human scan in a wide area and from a long distance. The other two cameras are high resolution video cameras with narrow field of view (NFOV) and IR filter & illuminators, mounted on a pan-tilt-unit (PTU) to capture the frontal view of human face and iris respectively. The WFOV detects the person and the NFOV cameras extract details for person identification. Once the frontal view shots are captured by the NFOV cameras, the face/iris models will be extracted by applying the state-of-the-art face/iris recognizers. In addition, a multimodality fusion approach integrates the face and iris recognition results to improve the overall recognition performance.