gebhart/patrepeval huggingface dataset:
Activation mechanism of prostaglandin endoperoxide synthetase by hemoproteins. (1982)

The mechanism of the activation of prostaglandin endoperoxide synthetase by hemeproteins was investigated using the enzyme purified from bovine seminal vesicle microsomes. At pH 8, the maximal enzyme activities with methemoglobin (2 microM), indoleamine 2,3-dioxygenase (2 microM), and metmyoglobin (2 microM) were 70%, 42%, and 15% of that with 1 microM hematin. Apomyoglobin and apohemoglobin inhibited the enzyme activities caused by hemoproteins as well as that caused by hematin. The inhibition was removed by the addition of excess hematin. The dissociation of heme from hemoproteins was demonstrated by trapping the free heme with human albumin or to a DE-52 column. The dissociation of heme from methemoglobin was facilitated by increasing concentrations of arachidonic acid. The amount of heme dissociated from hemoproteins (methemoglobin, metmyoglobin, and indoleamine 2,3-dioxygenase) in the presence of arachidonic acid correlated with their stimulatory effects on the prostaglandin endoperoxide synthetase activity. Horseradish peroxidase and beef liver catalase, the hemes of which were not dissociated in the presence of arachidonic acid, were ineffective in activating prostaglandin endoperoxide synthetase. Spectrophotometric titration of prostaglandin endoperoxide synthetase with hematin demonstrated that the enzyme bound hematin at the ratio of 1 mol/mol with an association constant of 0.6 x 10(8) M-1. From these results, we conclude that hemoproteins themselves are ineffective in activating prostaglandin endoperoxide synthetase and free hematin dissociated from the hemoproteins by the interaction of arachidonic acid is the activating factor for the enzyme.
Biomechanical evaluation of a fiber-reinforced composite prosthesis supported by implants with and without a microthread collar design (2010)

A fiber-reinforced composite (FRC) resin system was introduced as an alternative for implant-retained fixed dental prostheses (FDPs); however, the stress distribution in the bone around the implants which support the FRC-FDP has so far not been reported. The aim of this study was to investigate the biomechanical behavior of FRC-FDPs supported by implants with different collar geometries. A 3-dimensional finite element analysis method was selected to evaluate the stress distribution. FRC-FDPs were supported by 2 different dental implant systems with 2 distinct collar geometries: a microthread collar structure (MCS) and a non-MCS (NMCS). In separate load cases, 300-N vertical, 150-N oblique, and 60-N horizontal forces were simulated. Tensile and compressive stress values in the cortical and cancellous bone and von Mises stresses in the fixture-abutment complex, the framework, and veneer material were calculated. The MCS model revealed higher compression stresses at the cortical bone than did the NMCS model under all 3 load conditions. Moreover, higher tensile stresses under the oblique loads at the cortical bone were shown with the MCS model. In each model, stresses were much higher in the implant–abutment complex than in the cortical bone, and they were very low in the cancellous bone. Although additional experimental and clinical studies are needed, FRC-FDPs can be considered a suitable and alternative treatment choice for an implant-supported prosthesis. The implant design and geometry affect the load-transmission mechanisms. Implants with an MCS that supports FRC-FDPs were shown to be superior in terms of the stress distribution in the bone around the implant compared to implants with an NMCS.
The microstructure of laminin-111 compensates for dystroglycan loss in functional differentiation of mammary epithelial cells (2019)

Abstract: Laminin-111, an extracellular matrix (ECM) glycoprotein found in the basement membrane of mammary gland epithelia, is essential for lactation. In mammary epithelial cells, dystroglycan (Dg) is believed to be necessary for polymerization of laminin-111 into networks, thus we asked whether correct polymerization could compensate for Dg loss. Artificially polymerized laminin-111 and the laminin-glycoprotein mix Matrigel, both formed branching, spread networks with fractal dimensions from 1.7-1.8, whereas laminin-111 in media formed small aggregates without fractal properties (a fractal dimension of 2). In Dg knockout cells, either polymerized laminin-111 or Matrigel readily attached to the cell surface, whereas aggregated laminin-111 did not. In contrast, polymerized and aggregated laminin-111 bound similarly to Dg knock-ins. Both polymerized laminin-111 and Matrigel promoted cell rounding, clustering, formation of tight junctions, and expression of milk proteins, whereas aggregated Ln-1 did not attach to cells or promote functional differentiation. Highlights Laminin assembles into a fractal network when in presence of either the cell surface receptor dystroglycan or acidic glycoproteins or an acidic buffer. When this microstructure is recreated with an acidic treatment, laminin binds readily to dystroglycan null cells and induces functional differentiation of mammary epithelial cells.
Na3Mn4Te2O12 (1998)

The title compound, sodium manganate tellurate, was obtained by hydrothermal synthesis and adopts a superstructure related to the CaFe2O4 structure type, with the Mn and Te atoms ordered along the b axis (short axis in the CaFe2O4 structure). Electron counting schemes show that this compound is a mixed-valence MnII/MnIII compound, and bond valence sums are used to suggest that there is no site preference for the higher charged Mn atom.
Wind Ion-drift Neutral Composition Suite cathode activation procedure and current–voltage characteristics (2013)

The Wind Ion-drift Neutral Composition Suite (WINCS) uses three BaO thermionic cathodes in three ion sources for its neutral air measurements. The cathode activation procedure, obtained in laboratory measurements on a series of stock WINCS cathodes, ensures optimum cathode emission and life. The procedure begins by heating the cathode to 300–500°C to evolve CO2 and other gaseous products of the binder and the BaCO3; then the cathode temperature is raised to above 900°C for breakdown to BaO and sintering some of the Ba into the tungsten substrate; finally, activation begins by applying a small extraction voltage to the anode in front of the cathode. After activation, the cathode is ready to operate with any selected anode voltage. Electron emission of the WINCS cathodes easily exceeds 1 mA, and the fraction transmitted through the WINCS anodes exceeds 10% as required for WINCS. A maximum electron kinetic energy of about 90 eV was established as safe, also providing optimal ionization efficiency.
Leishmania tropica in Morocco: infection in dogs (1991)

Journal Article Leishmania tropica in Morocco: infection in dogs Get access J. Dereure, J. Dereure 1Laboratoire de Parasitologie, 163 rue Auguste-Broussonnet, Montpellier, France Search for other works by this author on: Oxford Academic PubMed Google Scholar J.-A. Rioux, J.-A. Rioux 1Laboratoire de Parasitologie, 163 rue Auguste-Broussonnet, Montpellier, France Search for other works by this author on: Oxford Academic PubMed Google Scholar M. Gallego, M. Gallego 2Departamento de Parasitologia, Facultad de Farmacia, Barcelona, Spain Search for other works by this author on: Oxford Academic PubMed Google Scholar J. Perières, J. Perières 1Laboratoire de Parasitologie, 163 rue Auguste-Broussonnet, Montpellier, France Search for other works by this author on: Oxford Academic PubMed Google Scholar F. Pratlong, F. Pratlong 1Laboratoire de Parasitologie, 163 rue Auguste-Broussonnet, Montpellier, France Search for other works by this author on: Oxford Academic PubMed Google Scholar J. Mahjour, J. Mahjour 3Service de Parasitologie, Ministère de la Santé Publique, Rabat, Morocco Search for other works by this author on: Oxford Academic PubMed Google Scholar H. Saddiki H. Saddiki 3Service de Parasitologie, Ministère de la Santé Publique, Rabat, Morocco Search for other works by this author on: Oxford Academic PubMed Google Scholar Transactions of The Royal Society of Tropical Medicine and Hygiene, Volume 85, Issue 5, September-October 1991, Page 595, https://doi.org/10.1016/0035-9203(91)90356-4 Published: 01 September 1991 Article history Received: 23 April 1991 Revision received: 12 June 1991 Accepted: 13 June 1991 Published: 01 September 1991
3D Printing of Ridged FeS2 Cathodes for Improved Rate Capability and Custom-Form Lithium Batteries (2022)

Additive manufacturing can enable the fabrication of batteries in nonconventional form factors, enabling higher practical energy density due to improved material packing efficiency of power sources in devices. Furthermore, energy density can be improved by transitioning from conventional Li-ion battery materials to lithium metal anodes and conversion cathodes. Iron disulfide (FeS<sub>2</sub>) is a prominent conversion cathode of commercial interest; however, the direct-ink-write (DIW) printing of FeS<sub>2</sub> inks for custom-form battery applications has yet to be demonstrated or optimized. In this work, DIW printing of FeS<sub>2</sub> inks is used to systematically investigate the impact of ink solid concentration on rheology, film shape retention on arbitrary surfaces, cathode morphology, and electrochemical cell performance. We find that cathodes with a ridged interface, produced from the filamentary extrusion of highly concentrated FeS<sub>2</sub> inks (60-70% solids w/w%), exhibit optimal power, uniformity, and stability when cycled at higher rates (in excess of C/10). Meanwhile, cells with custom-form, wave-shaped electrodes (printed FeS<sub>2</sub> cathodes and pressed lithium anodes) are demonstrated and shown to exhibit similar performance to comparable cells in planar configurations, demonstrating the feasibility of printing onto complex geometries. Overall, the DIW printing of FeS<sub>2</sub> inks is shown to be a viable path toward the making of custom-form conversion lithium batteries. More broadly, ridging is found to optimize rate capability, a finding that may have a broad impact beyond FeS<sub>2</sub> and syringe extrusion.
A 2D to 3D conversion scheme based on depth cues analysis for MPEG videos (2010)

In this article, we propose a 2D to 3D video conversion scheme for MPEG videos. The difficulty for 2D/3D conversion problem lies on depth estimation/ assignment with insufficient information. Our depth assignment is based on the analyses of multiple cues, e.g., motion parallax, atmospheric perspective, texture gradient, linear perspective, and relative height, separately for the foreground objects and the background area. To fit more kinds of videos, the proposed depth assignment scheme is content-adaptive by segmenting a video into shots and classifying each of them into three categories for different conversion schemes. Subjective experiments show that the 3D stereo video generated by using our depth assignment scheme and the Depth Image Based Rendering (DIBR) technique presents little difference to that created based on the depth ground truths.
Nano-Scale Surface Morphology, Wettability and Osteoblast Adhesion on Nitrogen Plasma-Implanted NiTi Shape Memory Alloy (2009)

Plasma immersion ion implantation (PIII) is an effective method to increase the corrosion resistance and inhibit nickel release from orthopedic NiTi shape memory alloy. Nitrogen was plasma-implanted into NiTi using different pulsing frequencies to investigate the effects on the nano-scale surface morphology, structure, wettability, as well as biocompatibility. X-ray photoelectron spectroscopy (XPS) results show that the implantation depth of nitrogen increases with higher pulsing frequencies. Atomic force microscopy (AFM) discloses that the nano-scale surface roughness increases and surface features are changed from islands to spiky cones with higher pulsing frequencies. This variation in the nano surface structures leads to different surface free energy (SFE) monitored by contact angle measurements. The adhesion, spreading, and proliferation of osteoblasts on the implanted NiTi surface are assessed by cell culture tests. Our results indicate that the nano-scale surface morphology that is altered by the implantation frequencies impacts the surface free energy and wettability of the NiTi surfaces, and in turn affects the osteoblast adhesion behavior.
Spaciousness and Envelopment in Musical Acoustics (1996)

: Conventional wisdom holds that spaciousness and envelopment are caused by lateral sound energy in rooms, and that it is the early arriving lateral energy which is most responsible. However small rooms often have many early lateral reflections, but by common definition small rooms are not spacious. This paper (briefly) describes a series of experiments into the perception of spaciousness and envelopment. The perceptions are found to be related most commonly to the lateral (diffuse) energy in halls at least 50ms after the ends of notes (the background reverberation) and less often but importantly to the properties of the sound field as the notes are held. Experiments with orchestral music at high reverberant level indicate that it is the very late &amp;gt;300ms reflected energy which is most responsible for spaciousness. A measure for spaciousness - Lateral Early Decay Time (LEDT) is suggested, and results of this measure in several halls are given. A good match between the new measure and su...
13C‐methacetin breath test as a quantitative liver function test in patients with chronic hepatitis C infection: continuous automatic molecular correlation spectroscopy compared to isotopic ratio mass spectrometry (2007)

The MBT obtained by an easy to operate, automated BreathID provides results comparable with standard IRMS and differentiates fibrosis grades in patients with chronic hepatitis C infection.
Research and Design of Internet Public Opinion Analysis System (2009)

Internet is becoming a spreading platform for the public opinion. It is important to grasp the Internet public opinion in time and understand the trends of their opinion correctly. Text classification plays a fundamental role in a number of information management and retrieval tasks. But Web-page classification is much more difficult than pure-text classification due to a large variety of noisy information embedded in Web pages. In this paper, we propose a system scheme for the analysis of the Internet public opinion (IPO). We apply Web-page classification through summarization to extract the most relevant content from the Web pages and then pass them to standard text classification algorithms (NB or SVM). We comprehensive use text classification and text clustering algorithms, which have been shown to be efficient and effective for singly using. Through the result of the experiment,we have proved the superiority of the system systempsilas architecture in the system design.
BIOSYNTHESIS OF HUMAN CHORIONIC GONADOTROPHIN IN VITRO: INCORPORATION OF [14C]l-LEUCINE (1972)

SUMMARY Fresh human placental tissue from first trimester pregnancies was incubated with [ 14 C] l -leucine and the incorporation of the labelled amino acid into placental proteins was studied in both the soluble and the particulate fractions. Free [ 14 C] l -leucine was completely separated from labelled proteins by exhaustive dialysis. This was confirmed by Sephadex G-100 gel chromatography. In preliminary experiments, the total protein fraction from Sephadex was submitted to polyacrylamide gel electrophoresis; columns divided into ten sections were checked, fraction by fraction, for incorporated radioactivity and human chorionic gonadotrophin (HCG) potency, using a radioimmunoassay method. In all instances, the highest HCG activity corresponded to the highest incorporation of radioactivity. In subsequent experiments only those radioactive proteins were used which had the highest activity after chromatography. This peak was further divided into two parts which were submitted to polyacrylamide gel electrophoresis. Using the ascending limb of the peak which contained about 70% of the total HCG activity, there was complete agreement between the distribution of radioactivity and that of HCG activity, whereas the bulk of HCG radioimmunological activity in the descending limb could be dissociated from radioactive proteins. After absorption of the HCG-like protein with specific anti-HCG serum, HCG activity was completely neutralized and more than 95% of the corresponding radioactivity disappeared. Additional evidence for the presence of an HCG-like biosynthesized protein was obtained after DEAE-cellulose ion exchange chromatography of the products of the incubation. Here again, the HCG potency of the radioactive protein with the highest activity was completely neutralized after absorption with a specific antiserum: in this case, however, only some 60% of the total radioactivity present disappeared after absorption. The results indicate that human placental tissue can synthesize from l -leucine proteins possessing radioimmunological HCG activity.
Three-Dimensional Covalent Organic Frameworks with hea Topology (2021)

Three-dimensional (3D) covalent organic frameworks (COFs) are a new type of crystalline organic porous material, which have great application potential in various fields due to their complex pore structures and fully exposed active sites. The synthesis of 3D COFs with novel topologies is still challenging on account of limited secondary building units. Herein, we report a 3D COF with hea topology, which has never been reported before, utilizing a D3h-symmetric precursor [2,3,6,7,14,15-hexakis(4-formylphenyl)triptycene (HFPTP)] and [tetrakis(4-amino biphenyl)methane (TABPM)]. 3D-hea-COFs display permanent porosity and a Brunauer–Emmett–Teller surface area of 1804.0 m2 g–1. Owing to the huge internal free volume of triptycene, 3D-hea-COFs show good adsorption performance for H2, CO2, and CH4. Moreover, theoretical calculation reveals that both triptycene and tetraphenylmethane units contribute to enhance hydrogen storage capacity. The novel topology in this work expands the family of 3D COFs and provides new possibilities for designing efficient gas storage materials.
In situ preparation of 3D graphene aerogels@hierarchical Fe3O4 nanoclusters as high rate and long cycle anode materials for lithium ion batteries (2014)

We describe a novel strategy for in situ fabrication of hierarchical Fe3O4 nanoclusters-GAs. Fe3O4 NCs-GAs deliver excellent rate capability (the reversible capacities obtained were 1442, 392 and 118 mA h g(-1) at 0.1C, 12C and 35C rates), and a high reversible capacity of 577 mA h g(-1) over 300 cycles at the current density of 5.2 A g(-1) (6C).
Analysis of proteins of mouse sarcoma pseudotype viruses: type-specific radioimmunoassays for ecotropic virus p30's. [/sup 125/I tracer technique] (1979)

Murine sarcoma virus pseudotypes were prepared by infection of nonproducer cells (A1-2), which were transformed by the Gazdar strain of mouse sarcoma virus, with Gross (N-tropic), WN1802B (B-tropic), or Moloney (NB-tropic) viruses. The respective host range pseudotype sarcoma viruses were defined by the tritration characteristics on cells with the appropriate Fv-1 genotype. Proteins from virus progeny were analyzed by sodium dodecyl sulfate--polyacrylamide gel electrophoresis. Bands present in both the 65,000- and the 10,000- to 20,000-molecular-weight regions of the gel distinguished the pseudotype viruses from their respective helpers. Furthermore, two protein bands were noted in the p30 region of murine sarcoma virus (Gross), one corresponding to Gross virus p30, and another of slightly slower mobility. However, since the mobility of the putative sarcoma p30 is nearly indentical to that of WN1802B, its presence could not be established by sodium dodecyl sulfate--polyacrylamide gel electrophoresis. Type-specific radioimmunossays for Gross virus p30 and for WN1802B p30 were applied for analysis of pseudotype preparations, and among several ecotropic viruses tested, only the homologous virus scored in the respective assay. By use of these assays, pseudotype viruses were found to contain only 8 to 48% helper-specific p30's; the remainder is presumably derived from the sarcoma virus.
Late Neolithic phytolith and charcoal records of human activities and vegetation change in Shijiahe culture, Tanjialing site, China (2017)

There is significant archaeological evidence marking the collapse of the Shijiahe culture in the middle reaches of the Yangtze River in China during the late Neolithic Period. However, the causes for this cultural collapse remain unclear. Our sedimentary records from a 3.3 m long profile and 76 phytolith and charcoal samples from the Tanjialing archaeological sites provide records of interactions between an ancient culture and vegetation change. During the early Shijiahe culture (c, 4850-4400 cal BP), the climate was warm and humid. Fire was intensively used to clear the vegetation. In the mid-period of the Shijiahe culture (c, 4400-4200 cal BP), the climate became slightly dry-cold and this was accompanied by decreasing water, leading to settlements. From c, 4200 cal BP, severe drought eroded the economic foundation of rice-cultivation. These conditions forced people to abandon the Shijiahe ancient city to find water in other regions, leading to the collapse of the Shijiahe culture.
An algebraic polyphase approach to wireless network coding (2009)

Network coding has been shown to improve throughput, minimize delay and economize the energy requirements in wireless networks. This paper presents an algebraic polyphase approach to the wireless linear network coding problem. By modeling wireless nodes as consisting of linear periodic time varying filters, the model incorporates realistic constraints including omni directionality of transmissions, half-duplex operation and interference effects. A rank criterion is introduced, which together with the transmission constraints, constitutes the necessary and sufficient conditions for the existence of a wireless network code.
[Surgical treatment of cataract]. (2005)

Today, the most frequently performed of all operative interventions is considered to be surgery for cataract. Modern surgical techniques applied under local anesthesia, tiny incisions that close spontaneously, reliable biometric methods, and the availability of artificial lenses, all combine to produce excellent results. In view of the low complication rate, this procedure can be recommended even in very old patients.
Highly Active and Selective Manganese C=O Bond Hydrogenation Catalysts: The Importance of the Multidentate Ligand, the Ancillary Ligands, and the Oxidation State (2016)

The replacement of expensive noble metals by earth-abundant transition metals is a central topic in catalysis. Herein, we introduce a highly active and selective homogeneous manganese-based C=O bond hydrogenation catalyst. Our catalyst has a broad substrate scope, it is able to hydrogenate aryl-alkyl, diaryl, dialkyl, and cycloalkyl ketones as well as aldehydes. A very good functional group tolerance including the quantitative and selective hydrogenation of a ketone in the presence of a non-shielded olefin is observed. In Mn hydrogenation catalysis, the combination of the multidentate ligand, the oxidation state of the metal, and the choice of the right ancillary ligand is crucial for high activity. This observation emphasizes an advantage and the importance of homogeneous catalysts in 3d-metal catalysis. For coordination compounds, fine-tuning of a complex coordination environment is easily accomplished in comparison to enzyme and/or heterogeneous catalysts.