gebhart/patrepeval huggingface dataset:
Interaction between polyelectrolyte and surfactant of opposite charge: hydrodynamic effects in the sodium hyaluronate/tetradecyltrimethylammonium bromide/sodium chloride/water system (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTInteraction between polyelectrolyte and surfactant of opposite charge: hydrodynamic effects in the sodium hyaluronate/tetradecyltrimethylammonium bromide/sodium chloride/water systemAasa Hersloef, Lars Olof Sundeloef, and Katarina EdsmanCite this: J. Phys. Chem. 1992, 96, 5, 2345–2348Publication Date (Print):March 1, 1992Publication History Published online1 May 2002Published inissue 1 March 1992https://pubs.acs.org/doi/10.1021/j100184a061https://doi.org/10.1021/j100184a061research-articleACS PublicationsRequest reuse permissionsArticle Views251Altmetric-Citations50LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Captopril reduces aortic and microvascular growth in hypertensive and normotensive rats. (1990)

This experiment was designed to investigate the effect of converting enzyme inhibition on functional and structural vascular alterations in one-kidney, one clip hypertensive rats and in normotensive rats. Starting 1 day before surgery, 100 mg/kg/day captopril was given chronically to half of the hypertensive and normotensive groups in their drinking water. With use of intravital microscopy in the cremaster muscle, arteriolar dimensions were measured 4 weeks later, both before and after topical application of 10(-3) M adenosine. Mean blood pressure was 124 +/- 4 mm Hg in control rats and 103 +/- 5 mm Hg in captopril-treated control rats (p less than 0.05). Mean blood pressure was significantly elevated to 183 +/- 5 mm Hg in captopril-treated one-kidney, one clip hypertensive rats and 193 +/- 5 mm Hg in one-kidney, one clip hypertensive rats. With use of histological techniques, a marked reduction of medial-intimal area of the abdominal aorta was found in captopril-treated control rats (24%), and hypertrophy of the aortic wall in one-kidney, one clip hypertensive rats was decreased 26% by captopril. Structural diameter reductions occurred in large arterioles of the captopril-treated control and hypertensive groups and the nontreated hypertensive group. In spite of a significant increase in wall-to-lumen ratio of first-order arterioles in all captopril-treated rats, captopril decreased cross-sectional wall area of these vessels 37% in hypertensive and 20% in control rats, respectively. Measured by stereological techniques, small arteriolar density decreased 30% in captopril-treated hypertensive rats and 17% in captopril-treated control rats. Therefore, smaller arteriolar lumens, decreased aortic and arteriolar cross-sectional wall area, and arteriolar rarefaction after converting enzyme inhibition, in spite of rising or falling blood pressure, are evidence that vascular growth was inhibited in vivo.
Enantioselective Fluorination of tert-Butoxycarbonyl Lactones and Lactams Catalyzed by Chiral Pd(II)-Bisphosphine Complexes (2006)

An efficient catalytic enantioselective fluorination of tert-butoxycarbonyl lactones and lactams is reported. Reactions of the lactone substrates proceeded smoothly in an alcoholic solvent with a catalytic amount of chiral Pd(II) complex. In the case of the less acidic lactam substrates, concurrent use of the Pd complex and 2,6-lutidine as a cocatalyst was effective. Under the reaction conditions, the fluorinated lactones and lactams were obtained in good yield with excellent enantioselectivity (94-99% ee).
Die Stilllegung eines CO2-Speichers – Pilotstandort Ketzin (2016)

Film 7: "Die Stilllegung eines CO2-Speichers – Pilotstandort Ketzin" (Länge 10:39)\n\n\n\nProduktionsjahr: 2015\n\n\n\n
Photodynamic therapy results in induction of WAF1/CIP1/P21 leading to cell cycle arrest and apoptosis (1998)

Photodynamic therapy (PDT) is a promising new modality that utilizes a combination of a photosensitizing chemical and visible light for the management of a variety of solid malignancies. The mechanism of PDT-mediated cell killing is not well defined. We investigated the involvement of cell cycle regulatory events during silicon phthalocyanine (Pc4)-PDT-mediated apoptosis in human epidermoid carcinoma cells A431. PDT resulted in apoptosis, inhibition of cell growth, and G0-G1 phase arrest of the cell cycle, in a time-dependent fashion. Western blot analysis revealed that PDT results in an induction of the cyclin kinase inhibitor WAF1/CIP1/p21, and a down-regulation of cyclin D1 and cyclin E, and their catalytic subunits cyclin-dependent kinase (cdk) 2 and cdk6. The treatment also resulted in a decrease in kinase activities associated with all the cdks and cyclins examined. PDT also resulted in (i) an increase in the binding of cyclin D1 and cdk6 toward WAF1/CIP1/p21, and (ii) a decrease in the binding of cyclin D1 toward cdk2 and cdk6. The binding of cyclin E and cdk2 toward WAF1/CIP1/p21, and of cyclin E toward cdk2 did not change by the treatment. These data suggest that PDT-mediated induction of WAF1/CIP1/p21 results in an imposition of artificial checkpoint at G1 --> S transition thereby resulting in an arrest of cells in G0-G1 phase of the cell cycle through inhibition in the cdk2, cdk6, cyclin D1, and cyclin E. We suggest that this arrest is an irreversible process and the cells, unable to repair the damages, ultimately undergo apoptosis.
Dynamic simulation of thin fibre growth (1993)

A thermocapillary model is developed for solving unsteady, axisymmetric phase change problem associated with free/moving interfaces, and applied to study the dynamic characteristics of edge-defined film-fed growth process. The numerical method is based on an Lagrangian/Eulerian approach, and yields solutions of the thermal field of each phase, and the phase boundary and meniscus profile as functions of time. The dynamic behavior of the fibre growth process with respect to the external disturbances, including the base temperature perturbation and the pull speed perturbation, is investigated. For both types of perturbation, fibre radius and solid/melt interface shape vary with the external forcing at the same frequencies; however, the magnitudes of their variations with respect to these perturbations are found to be dependent on the forcing frequencies. The similarities and differences of the effects of the different forcing mechanisms on the fibre growth dynamics are examined.
Using a Modified Yeast Two-Hybrid System to Screen for Chemical GEF Inhibitors (2012)

GTPases of the Ras superfamily act as signaling switches, active when bound to GTP and inactive when bound to GDP. There is now considerable evidence that over-activation of Ras-like pathways participates in the development of many cancer types. In particular, GTPases of the Rho family control cell adhesion, survival, motility, and invasion, cell properties dysregulated in most cancer types. Rho activation is triggered by RhoGEFs, most of which form complexes with growth-factor receptors and initiate downstream Rho signaling pathways in response to extracellular clues. As such, RhoGEFs represent attractive targets to inhibit Rho pathways and may have interesting druggability for cancer therapeutics. Here we describe a procedure derived from the yeast two-hybrid system, in which activation of a mammalian Rho GTPase by its cognate RhoGEF is converted into variation in the yeast growth. The experimental design is thus suitable for identiying RhoGEF inhibitors and has been optimized for medium-throughput screening. The major advantages of this method lie in the direct monitoring of GEF activity in a living organism and the rapid detection of false positive hits.
Development of a rice herbicide, fenquinotrione (2022)

Fenquinotrione is a novel rice herbicide that was discovered and developed by Kumiai Chemical Industry Co., Ltd. It can control a wide range of broadleaf and sedge weeds with excellent rice selectivity at 30 g a.i./10 a and is as effective as the wild type on acetolactate synthase inhibitor-resistant weeds. Our metabolic and molecular biological studies showed that CYP81A6-mediated demethylation and subsequent glucose conjugation are responsible for the safety of fenquinotrione in rice. Fenquinotrione was registered in Japan in 2018, and various products containing fenquinotrione have been launched. With its high efficacy and excellent rice selectivity, we believe that fenquinotrione will contribute to efficient food production in the future.
Continuous recrystallization during thermomechanical processing of a superplastic Al-10Mg-0.1Zr alloy (1990)

Microstructural evolution via static continuous recrystallization during thermomechanical processing of an Al-Mg-Zr alloy is addressed. Mechanical property data demonstrated that as-rolled material was capable of superplastic response without further treatment. Further, superplastic ductility at 300 C was enhanced by a factor of five by increasing the reheating time between rolling passes during processing also at 300 C. This enhanced ductility was associated with a Cu-texture and a microstructure consisting of predominantly high-angle boundaries. Processing to minimize recovery resulted in a strong Brass-texture component, a predominantly low-angle boundary microstructure and poorer ductility.
Radiation Environment Effects on an Erbium-doped Fiber Amplifier (2003)

International audience
A Rapid and Convenient Synthesis of Homoallylic Alcohols by the Barbier—Grignard Reaction. (2005)

ChemInformVolume 36, Issue 7 Isocyclic Compounds A Rapid and Convenient Synthesis of Homoallylic Alcohols by the Barbier—Grignard Reaction. Grant J. Sormunen, Grant J. Sormunen Dep. Chem., Univ. Wis., Eau Claire, WI 54702, USASearch for more papers by this authorDavid E. Lewis, David E. Lewis Dep. Chem., Univ. Wis., Eau Claire, WI 54702, USASearch for more papers by this author Grant J. Sormunen, Grant J. Sormunen Dep. Chem., Univ. Wis., Eau Claire, WI 54702, USASearch for more papers by this authorDavid E. Lewis, David E. Lewis Dep. Chem., Univ. Wis., Eau Claire, WI 54702, USASearch for more papers by this author First published: 18 January 2005 https://doi.org/10.1002/chin.200507073Citations: 1Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article.Citing Literature Volume36, Issue7February 15, 2005 RelatedInformation
Inhibition of Phospho-S6 Kinase, a Protein Involved in the Compensatory Adaptive Response, Increases the Efficacy of Paclitaxel in Reducing the Viability of Matrix-Attached Ovarian Cancer Cells (2016)

Addition of BX795 or CCT128930 to inhibit pS6 (S240/S244) or pS6 (S235/S236) restricted the compensatory adaptive response to paclitaxel in HeyA8 and SKOV3 cells. These inhibitors increased the efficacy of paclitaxel in reducing cancer cell viability.
The Future of Biologic Agents in the Treatment of Sjögren’s Syndrome (2007)

The gain in knowledge regarding the cellular mechanisms of T and B lymphocyte activity in the pathogenesis of Sjögren's syndrome (SS) and the current availability of various biological agents (anti-TNF-alpha, IFN- alpha, anti-CD20, and anti-CD22) have resulted in new strategies for therapeutic intervention. In SS, various phase I and II studies have been performed to evaluate these new strategies. Currently, B cell-directed therapies seem to be more promising than T cell-related therapies. However, large, randomized, placebo-controlled clinical trials are needed to confirm the promising results of these early studies. When performing these trials, special attention has to be paid to prevent the occasional occurrence of the severe side effects.
A scanning ocular spectrofluorophotometer. (1988)

We describe an instrument called a scanning ocular spectrofluorophotometer (SOSF) that measures fluorescence in a two-dimensional cross-section through the anterior chamber and cornea and provides the ability to change excitation and emission wavelengths rapidly. The output of a xenon arc lamp is filtered by a diffraction grating monochromator which has a bandpass of 4 nm and a range of 400 to 800 nm. Light emitted from the fluorophore is filtered by a variable wavelength interference filter which has a bandpass of approximately 11 nm and a range of 400 to 700 nm. To demonstrate the versatility of the instrument, we measured the spectra of fluorescein, fluorescein glucuronide and rhodamine B in the anterior chambers and corneas of pigmented rabbits after topical administration. We also measured simultaneously and independently the redistribution and disappearance of a mixture of fluorescein-labeled dextran and rhodamine B after intracameral injection. Rhodamine B was very rapidly absorbed by the cornea and lens while fluorescein-dextran was not measurable in the cornea before 4 hr. The SOSF provides a means of carrying out spectrofluorophotometry in the living eye and carrying out kinetic experiments which would otherwise be awkward or impossible.
A Dynamic Motion Control Technique for Human-like Articulated Figures (2001)

This paper presents a dynamic motion control technique for human-like articulated figures in a physically based character animation system. This method controls a figure such that the figure tracks input motion specified by a user. When environmental physical input such as an external force or a collision impulse are applied to the figure, this method generates dynamically changing motion in response to the physical input. We have introduced comfort and balance control to compute the angular acceleration of the figure's joints. Our algorithm controls the several parts of a human-like articulated figure separetely through the minimum number of degrees-of-freedom. Using this approach, our algorithm simulates realistic human motions at efficient computational cost. Unlike existing dynamic simulation systems, our method assumes that input motion is already realistic, and is aimed at dynamically changing the input motion in real-time only when unexpected physical input is applied to the figure. As such, our method works efficiently in the framework of current computer games.
Design and realization of 3D visualization system for real-time rendering of large-scale terrain (2010)

In order to achieve a regular-grid based, prospect -dependent 3D visualization system, this paper adopts Pyramid Model, and organizes the terrain data using Linear Quadtree. A method to compute the visible area and the best resolution for terrain is introduced in this paper, as well as an algorithm for predicting the data blocks. A new algorithm called as "Dynamic search algorithm for target blocks taking FPS into account", is brought forward in this paper. A 3D visualization system for large-scale terrain is realized by DirectX9.0 and Visual C#.NET, which achieved a good visual effect and a high and steady FPS just on PC platforms. The experimental result indicates that, the methods or algorithms presented in this paper can not only realize real-time rendering of large-scale terrain, but also can balance between the runtime efficiency and the display precision.
Long-Distance Electrical and Calcium Signals Evoked by Hydrogen Peroxide in Physcomitrella (2023)

Abstract Electrical and calcium signals in plants are one of the basic carriers of information transmitted over a long distance. Together with reactive oxygen species (ROS) waves, electrical and calcium signals can participate in cell-to-cell signaling, conveying information about different stimuli, e.g. abiotic stress, pathogen infection, or mechanical injury. There is no information on the ability of ROS to evoke systemic electrical or calcium signals in the model moss Physcomitrella and on the relationships between these responses. Here, we show that external application of hydrogen peroxide evokes electrical signals in the form of long-distance changes in the membrane potential, which transmit through the plant instantly after stimulation. The responses were calcium dependent, since their generation was inhibited by lanthanum, a calcium channel inhibitor (2 mM) or EDTA, a calcium chelator (0.5 mM). The electrical signals were partially dependent on glutamate receptor ion channels (GLR), since the knockout of GLR genes only slightly reduced the amplitude of the responses. The basal part of the gametophyte, which is rich in protonema cells, was the most sensitive to hydrogen peroxide. The measurements carried out on the protonema expressing fluorescent calcium biosensor GCaMP3 proved that. We also demonstrate upregulation of a stress-related gene which appears in a distant section of the moss 8 minutes after H 2 O 2 treatment. The results help to understand the importance of both types of signals in the transmission of information about the appearance of ROS in the plant cell apoplast.
Recent results of blue and green InGaN laser diodes for laser projection (2011)

Mobile laser projection is of great commercial interest. Today, a key parameter in embedded mobile applications is the optical output power and the wall plug efficiency of blue and green lasers. We report on improvements of the performance of true blue riedge waveguide InGaN lasers at 452nm with cw-output power up to 800mW in overstress and mono mode operation up to 500mW in a temperatures range of 20&deg;C to 80&deg;C. We succeeded in high and almost temperature independent wall plug efficiencies &gt;20% at stable output power levels from 200 to 500mW in cw-operation. Due to several improvements of our blue laser diodes we now estimate life times is in the order of 40khrs for 80mW output power in cw-operation at 40&deg;C. Additional overstress degradation tests at power levels up to 200mW show a strong dependency of lifetime with output power. Furthermore, we present pioneering results on true green InGaN laser diodes on c-plane GaN-substrates. The technological challenge is to achieve In-rich InGaN-quantum wells with sufficiently high material quality for lasing. We investigated the competing recombination processes below laser threshold like nonradiative defect recombination by electro-optical measurements, such confirming that low defect densities are essential for stimulated emission. A model for alloy fluctuations in In-rich InGaN-MQWs based on spectral and time resolved photoluminescence measurements yields potential fluctuations in the order of E<sub>0</sub>=57meV for our blue laser diodes. To get a closer insight into the physics of direct green InGaN-Laser we investigated the inhomogeneous broadening of experimentally measured gain curves via Hakki-Paoli-measurements in comparison to calculated gain spectra based on microscopic theory showing the importance of strong LO-phonon coupling in this material system. Investigations of current dependent gain measurements and calculations yield a factor of 2 higher inhomogeneous broadening for our green lasers than for our blue laser diodes on c-plane GaN. Based on the improvements of the material quality and design we demonstrate true green InGaN-Laser in cw-operation at 522nm with more than 80mW output power on c-plane GaN. The combination of low laser threshold ~60-80mA, high slope efficiency ~0.65W/A and low operating voltage 6.9-6.4V of our green monomode RWG-Laser results in a high wall plug efficiency of 5-6% in a temperature range of 20-60&deg;C.
[Fracture of the scaphoid carpal bone secondary to an intraosseous cyst. Apropos of a case]. (1998)

The authors report a cases of scaphoid fracture secondary to an intraosseous cyst in a young patient performing a high-risk sport. Intraosseous synovial cyst is a frequent and usually asymptomatic disease. Its aetiology remains controversial. No cases of fracture have been previously described. Our patient may have presented several risk factors for scaphoid fracture secondary to a synovial cyst.
Serum oxidized low-density lipoprotein decreases in response to statin therapy and relates independently to reductions in coronary plaque in patients with HIV (2015)

Statins lower oxLDL levels in HIV-infected patients, and reductions in oxLDL are related to improvements in coronary atherosclerosis, independent of traditional cardiovascular risk factors. Reductions in oxLDL may be one mechanism through which statins exert beneficial effects on reducing atherosclerosis in HIV-infected individuals.
Need for Tweet (2020)

Social media, especially Twitter, has always been a part of the professional lives of software developers, with prior work reporting on a diversity of usage scenarios, including sharing information, staying current, and promoting one's work. However, previous studies of Twitter use by software developers typically lack information about activities of the study subjects (and their outcomes) on other platforms. To enable such future research, in this paper we propose a computational approach to cross-link users across Twitter and GitHub, revealing (at least) 70,427 users active on both. As a preliminary analysis of this dataset, we report on a case study of 786 tweets by open-source developers about GitHub work, combining automatic characterization of tweet authors in terms of their relationship to the GitHub items linked in their tweets with qualitative analysis of the tweet contents. We find that different developer roles tend to have different tweeting behaviors, with repository owners being perhaps the most distinctive group compared to other project contributors and followers. We also note a sizeable group of people who follow others on GitHub and tweet about these people's work, but do not otherwise contribute to those open-source projects. Our results and public dataset open up multiple future research directions.
Effects of Prednisolone on the Development of Immune Responses to Canine Distemper Virus in Beagle Pups (1979)

Effects of oral prednisolone (OP) on the development of immune responses of Beagle pups to canine distemper virus (CDV) were studied. Dogs were treated with OP for 21 days, twice a day for the first 7 days, once a day for the next 7 days, and on alternate days for the last 7 days. Dogs given dosages of OP (1 mg/kg and 10 mg/kg) showed a normal in vivo immunogenic response after CDV vaccination and survived a virulent CDV challenge exposure, whereas non-treated, nonvaccinated dogs became ill or died after challenge exposure. The most marked effect of corticosteroid treatment on the immune system was the graded phytoimmunosuppressive effect upon the lymphocyte blast transformation test.