gebhart/patrepeval huggingface dataset:
CELL PHONE ADDICTION IN COLLEGE STUDENTS: A HANDS-ON LABORATORY EXPERIENCE FOR PSYCHOLOGY RESEARCH COURSES (2011)

Treatment intensity is a modifiable service factor that may positively influence health-related quality of life.Implications for rehabilitationIn addition to providing information on client progress towards attainment of individual treatment goals, routine collection of patient reported outcome measures within a community rehabilitation program can elicit information that can inform rehabilitation service improvement.Clients of a community rehabilitation program with a neurological or medical condition demonstrate the least improvement in overall health profile and may require additional rehabilitation or supports.Across all diagnostic groups, problems with anxiety and depression were least likely to improve following receipt of community rehabilitation. Improving access to psychological services and associated referral pathways in community rehabilitation services could improve these outcomes.Initiatives aimed at increasing intensity of therapy such as targeted triage and resource allocation, may improve health-related quality of life for clients of a community rehabilitation program with traumatic orthopaedic conditions.For clients with a neurological condition, initiatives aimed at increasing intensity of therapy may improve health-related quality of life in more complex patients with comorbid health conditions.
Hepatitis B Antigen: Antigenic Sites Related to Human Serum Proteins Revealed by Affinity Chromatography (1974)

Hepatitis B antigen-associated particles, isolated from sera of antigen carriers, were submitted to affinity chromatography on columns of insolubilized antibodies to normal human plasma. The particles adsorbed to the immunosorbent at pH 7.2 and were subsequently eluted at pH 2.2. Exposure of the particles to 8 M urea, 5 M KI, pH 2.2, detergents, organic solvents, or proteolytic enzymes failed to prevent their subsequent adsorption to the immunosorbent. This suggests that antigenic determinants related to human plasma proteins are constituent components of hepatitis B antigen-associated particles. These determinants are distinct from the group-specific (a) and subtype-specific (d or y) sites of the hepatitis B antigen and appear to be related to antigenic specificities on prealbumin, albumin, apolipoproteins C and D, and the gamma-chain of immunoglobulin G.
Prognostic implications of ploidy and proliferative activity in diffuse large cell lymphomas. (1986)

Paraffin-embedded surgical biopsies from 50 patients with newly diagnosed diffuse large cell lymphoma (DLCL) were examined for proliferative activity and DNA aneuploidy by flow cytometry. These results were correlated with the clinical characteristics of these patients and the course of their disease. High proliferative activity, defined as less than 80% of cells in G0 or G1, was found to be the single most important pretreatment adverse prognostic factor in these patients. This relationship remained significant after correcting for poor performance status and advanced Ann Arbor stage, the other factors found to be associated with a shortened survival. DLCLs with high proliferative activity were more probable to present with extranodal involvement than those with lower proliferative activity. The mitotic count as determined by light microscopy did not correlate with flow cytometry-defined proliferative activity and may be a less accurate method for assessing this important biological characteristic in DLCL. DNA aneuploidy was detected in 62% of cases but did not appear to have any prognostic significance. Biopsies from patients who presented with lymphomatous bone marrow involvement, however, invariably demonstrated an aneuploid stemline. These results suggest that differences in proliferative activity may be an important biological basis for the variable prognosis seen in DLCL.
Growth rate of abdominal aortic aneurysms as measured by computed tomography (1985)

Abstract The risk of rupture of an abdominal aortic aneurysm increases with size. It has thus been recommended that small aneurysms be continuously followed with some type of imaging technique to detect when aneurysm size constitutes an indication for surgery. The present study focuses on the growth rate of abdominal aortic aneurysms in 35 patients who were subjected to repeated computerized tomographic examinations of their abdominal aortic aneurysms. Several aneurysms were measured more than twice resulting in 57 different examinations. The mean growth rate of the transverse diameter was 0·52 cm/year. The individual growth rates were, however, variable. Aneurysms with an initial transverse diameter exceeding 6 cm showed a slightly but not significantly faster increase in size compared with smaller aneurysms. No correlation between initial size and growth rate could be established. Six patients died during the study period, two from myocardial infarction, three after elective aneurysm operations and one, refused for elective operation, died after rupture. It is concluded that the growth rate measured with computed tomography agrees well with previously reported estimates obtained with ultrasonography. It is recommended that small aneurysms particularly in patients with relative contraindications to surgery be followed with repeated examinations of size.
On the efficacy of using proton beams for estimating neutron-induced soft error rates (2017)

This work investigates the feasibility of using high energy proton beams in lieu of, or to complement, broad energy spectrum neutron beams for accelerated testing of the cosmic component of terrestrial soft error rates (SER). Logic and memory devices manufactured in three recent technologies were tested at various proton facilities and their single event upset cross sections compared to soft error rates measured at the Los Alamos Neutron Science Center (LANSCE). Linear energy transfer and soft error simulations were conducted to understand the limits of using proton beam facilities. Both simulation results and experimental data demonstrate that a good correlation between proton cross-section and LANSCE neutron SER can be established for tested devices and technologies.
On the Characteristics of Fatigue Fracture with Rapid Frequency Change (2023)

The effect of sudden variations in working modes and fatigue behavior of CS 1018 is studied. A general model based on the framework of the fracture fatigue entropy (FFE) concept is developed to capture such changes. Fully reversed bending tests are performed on flat dog bone specimens with a series of variable frequency tests without turning the machine off to simulate fluctuating working conditions. The results are then post-processed and analyzed to assess how fatigue life changes when a component is subjected to sudden changes in multiple frequencies. It is demonstrated that regardless of the frequency changes, FFE remains constant and stays within a narrow band range, similar to that of a constant frequency.
Endophotocoagulation to Retinal Pigment Epithelium as an Adjuvant Therapy in the Management of Retinal Detachment Caused by a Highly Myopic Macular Hole (2002)

Retinal detachment secondary to a highly myopic macular hole remains a particular surgical challenge. Pars plana vitrectomy, endophotocoagulation at the base of a macular hole in conjunction with fluid-gas exchange was performed in 4 consecutive patients with a mean refraction of -13.8D (range, -8D-(-)18D). Mean axial length was 27.5 mm (range, 26.0-29.0 mm). Mild atrophy of the retinal pigment epithelium was present in 3 patients while 1 patient had moderate atrophy. The mean follow-up period was 12 months (range, 6-18 months). The overall primary anatomical success rate was 75%. All 3 eyes with mild retinal pigment epithelium atrophy had retinal reattachment after one operation.
Decision-theoretic military operations planning (2004)

Military operations planning involves concurrent actions, resource assignment, and conflicting costs. Individual tasks sometimes fail with a known probability, promoting a decision-theoretic approach. The planner must choose between multiple tasks that achieve similar outcomes but have different costs. The military domain is particularly suited to automated methods because hundreds of tasks, specified by many planning staff, need to be quickly and robustly coordinated. The authors are not aware of any previous planners that handle all characteristics of the operations planning domain in a single package. This paper shows that problems with such features can be successfully approached by real-time heuristic search algorithms, operating on a formulation of the problem as a Markov decision process. Novel automatically generated heuristics, and classic caching methods, allow problems of interesting sizes to be handled. Results are presented on data provided by the Australian Defence Science and Technology Organisation.
Hot topic: Performance of bovine high-density genotyping platforms in Holsteins and Jerseys (2011)

Two high-density single nucleotide polymorphism (SNP) genotyping arrays have recently become available for bovine genomic analyses, the Illumina High-Density Bovine BeadChip Array (777,962 SNP) and the Affymetrix Axiom Genome-Wide BOS 1 Array (648,874 SNP). These products each have unique design and chemistry attributes, and the extent of marker overlap and their potential utility for quantitative trait loci fine mapping, detection of copy number variation, and multibreed genomic selection are of significant interest to the cattle community. This is the first study to compare the performance of these 2 arrays. Deoxyribonucleic acid samples from 16 dairy cattle (10 Holstein, 6 Jersey) were used for the comparison. An independent set of DNA samples taken from 46 Jersey cattle and 18 Holstein cattle were used to ascertain the amount of SNP variation accounted by the 16 experimental samples. Data were analyzed with SVS7 software (Golden Helix Inc., Bozeman, MT) to remove SNP having a call rate less than 90%, and linkage disequilibrium pruning was used to remove linked SNP (r² ≥ 0.9). Maximum, average, and median gaps were calculated for each analysis based on genomic position of SNP on the bovine UMD3.1 genome assembly. All samples were successfully genotyped (≥ 98% SNP genotyped) with both platforms. The average number of genotyped SNP in the Illumina platform was 775,681 and 637,249 for the Affymetrix platform. Based on genomic position, a total of 107,896 SNP were shared between the 2 platforms; however, based on genotype concordance, only 96,031 SNP had complete concordance at these loci. Both Affymetrix BOS 1 and Illumina BovineHD genotyping platforms are well designed and provide high-quality genotypes and similar coverage of informative SNP. Despite fewer total SNP on BOS 1, 19% more SNP remained after linkage disequilibrium pruning, resulting in a smaller gap size (5.2 vs. 6.9 kb) in Holstein and Jersey samples relative to BovineHD. However, only 224,115 Illumina and 241,038 Affymetrix SNP remained following removal of SNP with a minor allele frequency of zero in Holstein and Jersey samples, resulting in an average gap size of 11,887 bp and 11,018 bp, respectively. Combining the 354,348 informative (r² ≥ 0.9), polymorphic (minor allele frequency ≥ 0), unique SNP data from both platforms decreased the average gap size to 7,560 bp. Genome-wide copy number variant analyses were performed using intensity files from both platforms. The BovineHD platform provided an advantage to the copy number variant data compared with the BOS 1 because of the larger number of SNP, higher intensity signals, and lower background effects. The combined use of both platforms significantly improved coverage over either platform alone and decreased the gap size between SNP, providing a valuable tool for fine mapping quantitative trait loci and multibreed animal evaluation.
Reversible redox processes in main-group/transition-metal clusters: the [Sb2Co4(CO)10(.mu.-CO)]-/2- couple (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReversible redox processes in main-group/transition-metal clusters: the [Sb2Co4(CO)10(.mu.-CO)]-/2- coupleJ. Scott Leigh, Kenton H. Whitmire, Kyeong Ae Yee, and Thomas A. AlbrightCite this: J. Am. Chem. Soc. 1989, 111, 7, 2726–2727Publication Date (Print):March 1, 1989Publication History Published online1 May 2002Published inissue 1 March 1989https://pubs.acs.org/doi/10.1021/ja00189a063https://doi.org/10.1021/ja00189a063research-articleACS PublicationsRequest reuse permissionsArticle Views100Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Spatial Normalization of 3D Brain Images Using Deformable Models (1996)

We present a highly automated methodology for spatial normalization of images, using deformable models. Applications of our methodology include stereotactic normalization of functional and structural images, morphological analysis of the brain, and computer-aided neurosurgery.
Automatic extrinsic camera parameters estimation for a mobile ToF camera application (2015)

Extrinsic camera parameters estimation is an important task for many assistance systems. The reconstruction of the image to world projection depends strongly on robust estimated camera parameters. Based on the used camera system, the extrinsic parameters estimation can be a complicated task, that maybe requires a lot of computing capacity. In this paper, an extrinsic camera parameters estimation procedure for a time of flight sensor, equipped on a rollator for impaired people, is presented. Effectiveness and robustness of the procedure are in the focus of the developed calibration procedure. The precision of image to world projection based on the estimated parameters is evaluated. The influence of the sensor noise regarding the measured diagonal values, e.g. depth values in the vicinity of the principal point of the camera sensor, to the ground plane is evaluated, too. Many different viewing angles as well as different height configurations of the system setup are used to evaluate the accuracy of the estimation procedure.
Surface definition for branching, contour-defined objects (1981)

Recent work on mapping polygonal surface mosaics onto contour defined objects has resulted in minimum flow algorithms which do a good job of mapping a surface between two single contours. This report extends these algorithms to handle contour defined objects which are highly branched and have holes.For branching contours where n contours in section I are connected to m contours in section i+1, the surfaces are mapped by first concatenating the section I contours into a single large contour using a minimum number of minimum distance links, similarly concatenating the section I+1 contours, then performing the one to one mapping between the resulting composite contours.Capping off a single arbitrarily shaped contour may be done by computing the medial axis transform of the contour, constructing the medial axis contour and mapping a surface from the contour to the medial axis contour.Medial axis transforms of the section I+1 contours may also be projected onto section I and concatenated with the section I contours to handle the mapping of convoluted, highly branched objects. These algorithms have applications to three-dimensional CAT scanner data, topographical map data and object representation for knowledge guided vision systems.
In vitro mutagenesis of trypsinogen: role of the amino terminus in intracellular protein targeting to secretory granules. (1987)

The mouse anterior pituitary tumor cell line, AtT-20, targets secretory proteins into two distinct intracellular pathways. When the DNA that encodes trypsinogen is introduced into AtT-20 cells, the protein is sorted into the regulated secretory pathway as efficiently as the endogenous peptide hormone ACTH. In this study we have used double-label immunoelectron microscopy to demonstrate that trypsinogen colocalizes in the same secretory granules as ACTH. In vitro mutagenesis was used to test whether the information for targeting trypsinogen to the secretory granules resides at the amino (NH2) terminus of the protein. Mutations were made in the DNA that encodes trypsinogen, and the mutant proteins were expressed in AtT-20 cells to determine whether intracellular targeting could be altered. Replacing the trypsinogen signal peptide with that of the kappa-immunoglobulin light chain, a constitutively secreted protein, does not alter targeting to the regulated secretory pathway. In addition, deletion of the NH2-terminal "pro" sequence of trypsinogen has virtually no effect on protein targeting. However, this deletion does affect the signal peptidase cleavage site, and as a result the enzymatic activity of the truncated trypsin protein is abolished. We conclude that neither the signal peptide nor the 12 NH2-terminal amino acids of trypsinogen are essential for sorting to the regulated secretory pathway of AtT-20 cells.
Versatile carboxyl-terminus of capsid protein of porcine circovirus type 2 were recognized by monoclonal antibodies with pluripotency of binding (2017)

We designed the peptide (C3) mimetic carboxyl-terminus (Cterminus) of capsid protein of porcine circovirus type 2b (PCV2b-1A/1B) inducing humoral immunity and generating hybridomas. The positive reactivity of the mAbs to PCV2 capsid protein was demonstrated by Western blot assay. Those mAbs also showed positive signals on PCV2b infected swine lymphocytes by indirect immunofluorescence staining. The mAb 1H3 bound to three minimal linear epitopes (P62, DPPLNP; P67, DPPLNPK; P73, LKDPPLKP), which was located at Cterminus of the capsid protein of PCV2b-1A/1B, PCV2b-1C, and PCV2a-2A respectively. The mAbs 3B2 bound to only one minimal linear epitopes (P59, KDPPLNP). The mAbs 6B8 bound to two minimal linear epitopes (P59 and P67). Our data demonstrate the core motif (P62) within the P59 could be recognized by mAbs (3B2 and 6B8) in the free status by liquid phase blocking immunoassay (LPBI) but not be recognized by these mAbs in the fixed form on the plate by indirect ELISA (iELISA). However, the P73 could be recognized by mAb 1H3 by iELISA but no inhibition of the interactive binding of C3 and mAb 1H3 by LPBI. This study also indicated that IgM mAbs and defective Ig mAb have broad binding, moderate specificity and low affinity. This study confirm that mAbs have pluripotency of binding. It might be a phenomenon of antibody response to Cterminus of capsid protein of PCV2b.
Application of Sequential Quadratic Programming Algorithm based on region search method in reactive power optimization (2006)

In order to improve the convergence of reactive power optimization and the accuracy of optimization result, this paper proposes the sequential quadratic programming (SQP) algorithm based on region search method. The algorithm combines global SQP with trust-region search method. Through adding the trust-region constraint into SQP sub-question, the linear search method is improved to region search method and step length can be determined while search direction is solved. Moreover, calculating reactive power optimization in IEEE30 bus system and comparing with other methods, results show that the improved algorithm has great convergence and optimization effect
Low-Frequency Repetitive Transcranial Magnetic Stimulation over Right Dorsolateral Prefrontal Cortex in Parkinson’s Disease (2020)

Low-frequency rTMS of right DLPFC could be a potential selection in managing motor and nonmotor symptoms in PD.
An innovative application of 5GDHC: A techno-economic assessment of shallow geothermal systems potential in different European climates (2023)

Energy consumption for thermal purposes represents the most impacting energy issue in the European building sector. In addition to space heating, space cooling is constantly growing, due also to climate change, which provokes extreme hot events in summer even in moderate climates. To approach this challenge, it is essential to invest in lowering the overall energy demand, to increase the energy conversion efficiencies and to replace fossil fuels with renewable energy sources. The research here presented deals with the European decarbonization goals and focuses on shallow geothermal technology in district thermal systems (DTS), i.e. Geo-5GDHC. The research investigates whether Geo-5GDHC can be cost-effective in different scenarios based on climatic contexts, insulation levels and the possible integration of photovoltaic and thermal technology (PVT). Through the elaboration of proper KPIs and the implementation and use of a tool specifically developed to couple a Geo-5GDHC energy assessment model with an economic analysis (PILEDHC), the research highlights results and guidelines for providing solutions for new and innovative DTS, considering both energy and economic aspects in different contexts.
Steering the Ester and γ-Valerolactone Selectivities in Levulinic Acid Hydrogenation (2018)

Both alkyl esters and γ-valerolactone (GVL) derived from levulinic acid (LA) have applications as renewable transportation fuel/fuel additives. Non-noble metal cobalt supported on La2O3 catalyst was developed for efficient cascade LA hydrogenation to GVL via esterification. LA hydrogenation in methanol alone yielded methyl levulinate (MeLA) as a major product along with 43% of GVL. Interestingly, hydrogenation in water gave almost complete selectivity to GVL; nevertheless, it was associated with significant metal leaching. Suppression of metal leaching and enhancement in selectivity to GVL could be achieved by a methanol/water (95:5) solvent system. XRD analysis of La2O3-supported catalysts evidenced the characteristic peaks of a mixture of La2O3 and La(OH)3 phases. Basicity, as well as acidity, of the catalyst as determined by CO2 and NH3 TPD was due to these La2O3, Co–La, and La(OH)3 phases which played an important role in directing the product selectivity in levulinic acid hydrogenation. At the low temperature of 160 °C, almost equal selectivities of MeLA (47%) and GVL (43%) were observed, while higher temperature (200 °C) favored further hydrogenation of MeLA to GVL (75%). Similarly, with an increase in reaction time to 9 h, the GVL selectivity achieved was as high as 80%. The selectivity to MeLA and GVL in LA hydrogenation over Co/La2O3 catalyst can be altered by suitably adjusting the reaction conditions.
Status and outlook of emerging nonvolatile memory technologies (2005)

This paper reviews the concept, status and challenges of emerging nonvolatile memory technologies. The technologies that are discussed and compared to state of the art flash technology are the conductive bridging RAM (CBRAM), the ferro-electric RAM (FeRAM), the magneto-resistive RAM (MRAM), the organic RAM (ORAM) and the phase change RAM (PCRAM).