gebhart/patrepeval huggingface dataset:
MEGA: A search for the decay μ→eγ (1995)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation J. J. Szymanski, J. F. Amann, K. Baker, D. Barlow, K. Black, R. D. Bolton, M. Brooks, S. Carius, Y. Chen, M. D. Cooper, P. S. Cooper, J. Crocker, M. Dzemidzic, R. J. Fisk, J. Flick, W. Foreman, C. A. Gagliardi, D. Haim, A. Hallin, R. Harrison, G. Hart, C. M. Hoffman, G. E. Hogan, E. B. Hughes, E. V. Hungerford, K. Johnston, C. Jui, G. J. Kim, J. E. Knott, D. D. Koetke, M. A. Kroupa, T. Kozlowski, K. Lan, D. Lee, F. Liu, R. Manweiler, R. Marshall, B. W. Mayes, R. E. Mischke, F. J. Naivar, B. M. K. Nefkens, J. Novak, M. A. Oothoudt, J. N. Otis, R. Phelps, L. E. Piilonen, C. Pillai, L. Pinsky, J. Price, M. W. Ritter, S. Schilling, T. D. S. Stanislaus, K. M. Stantz, W. Stephens, J. Sturrock, L. Tang, B. Tippens, R. E. Tribble, X.‐L. Tu, L. A. Van Ausdeln, W. vonWitsch, D. Whitehouse, C. Wilkinson, B. Wright, S. C. Wright, Y. Zhang, W. Zhou, X.‐G. Zhou, K. O. H. Ziock; MEGA: A search for the decay μ→eγ. AIP Conf. Proc. 10 July 1995; 338 (1): 789–792. https://doi.org/10.1063/1.48450 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
Pharmacokinetics of ICG and HPPH-car for the Detection of Normal and Tumor Tissue Using Fluorescence, Near-infrared Reflectance Imaging: A Case Study ¶ (2000)

We present in vivo fluorescent, near-infrared (NIR), reflectance images of indocyanine green (ICG) and carotene-conjugated 2-devinyl-2-(1-hexyloxyethyl) pyropheophorbide (HPPH-car) to discriminate spontaneous canine adenocarcinoma from normal mammary tissue. Following intravenous administration of 1.0 mg kg-1 ICG or 0.3 mg kg-1 HPPH-car into the canine, a 25 mW, 778 nm or 70 mW, 660 nm laser diode beam, expanded by a diverging lens to approximately 4 cm in diameter, illuminated the surface of the mammary tissue. Successfully propagating to the tissue surface, ICG or HPPH-car fluorescence generated from within the tissue was collected by an image-intensified, charge-coupled device camera fitted with an 830 or 710 nm bandpass interference filter. Upon collecting time-dependent fluorescence images at the tissue surface overlying both normal and diseased tissue volumes, and fitting these images to a pharmacokinetic model describing the uptake (wash-in) and release (wash-out) of fluorescent dye, the pharmacokinetics of fluorescent dye was spatially determined. Mapping the fluorescence intensity owing to ICG indicates that the dye acts as a blood pool or blood persistent agent, for the model parameters show no difference in the ICG uptake rates between normal and diseased tissue regions. The wash-out of ICG was delayed for up to 72 h after intravenous injection in tissue volumes associated with disease, because ICG fluorescence was still detected in the diseased tissue 72 h after injection. In contrast, HPPH-car pharmacokinetics illustrated active uptake into diseased tissues, perhaps owing to the overexpression of LDL receptors associated with the malignant cells. HPPH-car fluorescence was not discernable after 24 h. This work illustrates the ability to monitor the pharmacokinetic delivery of NIR fluorescent dyes within tissue volumes as great as 0.5-1 cm from the tissue surface in order to differentiate normal from diseased tissue volumes on the basis of parameters obtained from the pharmacokinetic models.
Mechanical properties of vacuum-sintered yttria ceramics (1994)

Mechanical properties of vacuum sintered dense yttria ceramics have been studied. Values of flexural strength, fracture toughness and thermal shock behavior, better than those reported in the literature, are reported. Microscopic investigations reveal elastic strain energy and cleavage step formation as the major contributors to the fracture energy.
Boundary Learning by Optimization with Topological Constraints Supplementary Material (2010)

In this section we provide additional details of the experimental comparisons that were performed in Section 4 of the main text. We also show an extended presentation of the warping error results shown in the main text. In particular Figure 1 shows the warping error on the test set of the convolutional network methods along with BEL and gPb-OWT-UCM. For this comparison, a threshold of gPb-OWT-UCM and BEL was chosen according to the threshold that achieved lowest Rand error also on the test set (shown in Figure 4 of the main text). These results are consistent with the relative ordering of algorithms that the Rand index produced, but the relative reduction in error between the methods is larger (for example, the gPb-OWT-UCM method has almost ten times as much warping error as the highest performer, BLOTC CN). Figure 2 also shows a visual depiction of the segmentation and boundary maps of all methods that are discussed. 1.1. Multiscale Normalized Cut Multiscale normalized cut was performed using publicly available code provided by the authors of [1]:
Exposure to traffic exhaust and night cough during early childhood: the CCAAPS birth cohort (2009)

Though studies have investigated the association between air pollution and respiratory health outcomes in children, few have focused on night cough. The study objective was to simultaneously evaluate family factors (i.e., race, gender, maternal and paternal asthma, and breastfeeding), health (allergen sensitization and wheezing symptoms), home factors (dog, cat, mold, endotoxin, and dust mite), and other environmental exposures (traffic exhaust and second-hand tobacco smoke) for associations with recurrent dry night cough (RNC) during early childhood. A structural equation model with repeat measures was developed assessing RNC at ages one, two, and three. The prevalence of RNC was relatively large and similar at ages, one, two, and three at 21.6%, 17.3%, and 21.1%, respectively. Children exposed to the highest tertile of traffic exhaust had an estimated 45% increase in risk of RNC compared with children less exposed (adjusted OR 1.45, 95% CI: 1.09, 1.94). Also, wheezing was associated with a 76% higher risk of RNC (adjusted OR 1.76, 95% CI: 1.36, 2.26). A protective trend for breastfeeding was found with a 27% reduction in risk associated with breastfeeding (adjusted OR 0.73, 95% CI: 0.53, 1.01). No other factors were significant. These results suggest that traffic exhaust exposure may be a risk factor for night cough in young children.
Process planning with genetic algorithms on results of knowledge-based reasoning (1996)

The paper presents a new approach to solving even unusually complex problems of computer-aided process planning (CAPP). Main principles are based on the analysis of the roles and relations of CAPP in advanced manufacturing systems. Planning is carried out in several stages, by using both domain-specific knowledge and domain-independent, general methods. First, by knowledge-based reasoning, repertoires of plan elements and technological constraints are created that the final solutions must meet. Then, a global plan merging process generates plan variants so as to meet the given optimization objective. Among the various plan merging methods, one using genetic algorithms stands preeminent by its performance and robustness. Domain-specific knowledge, methods of reasoning and plan merging are described in detail.
Use of heat release and an internal RNA standard control in reverse transcription-PCR detection of Norwalk virus from stool samples (1997)

Norwalk virus (NV) and the Norwalk-like viruses are important human pathogens that cause epidemic acute viral gastroenteritis. Current techniques used to recover NV from clinical samples involve multistep viral extraction and elution procedures with subsequent viral detection by reverse transcription-PCR (RT-PCR). In this study, a simple method using heat to recover viral RNA from 45 stool samples was compared to a conventional viral RNA extraction technique, with subsequent analysis by RT-PCR. In addition, we used an internal RNA standard for the detection of inhibitors present in processed samples. Our results indicate that the use of heat to recover NV RNA from stool samples has a sensitivity for the detection of NV RNA that is similar to the more labor-intensive, time-consuming, conventional RNA extraction technique. The use of an RNA internal standard permits the detection of inhibitors present in processed samples, allowing the identification of false negatives. The standard we developed has the advantage of allowing differential detection between wild-type viral RNA and standard using internal oligoprobe hybridization.
Romosozumab in Postmenopausal Korean Women with Osteoporosis: A Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study (2021)

Background: This phase 3 study evaluated the efficacy and safety of 6-month treatment with romosozumab in Korean postmenopausal women with osteoporosis. Methods: Sixty-seven postmenopausal women with osteoporosis (bone mineral density [BMD] T-scores -2.5 at the lumbar spine, total hip, or femoral neck) were randomized (1:1) to receive monthly subcutaneous injections of romosozumab (210 mg; n=34) or placebo (n=33) for 6 months. Results: At month 6, the difference in the least square (LS) mean percent change from baseline in lumbar spine BMD (primary efficacy endpoint) between the romosozumab (9.5%) and placebo (-0.1%) groups was significant (9.6%; 95% confidence interval, 7.6 to 11.5; P<0.001). The difference in the LS mean percent change from baseline was also significant for total hip and femoral neck BMD (secondary efficacy endpoints). After treatment with romosozumab, the percent change from baseline in procollagen type 1 Nterminal propeptide transiently increased at months 1 and 3, while that in C-terminal telopeptide of type 1 collagen showed a sustained decrease. No events of cancer, hypocalcemia, injection site reaction, positively adjudicated atypical femoral fracture or osteonecrosis of the jaw, or positively adjudicated serious cardiovascular adverse events were observed. At month 9, 17.6% and 2.9% of patients in the romosozumab group developed binding and neutralizing antibodies, respectively. Conclusion: Treatment with romosozumab for 6 months was well tolerated and significantly increased lumbar spine, total hip, and femoral neck BMD compared with placebo in Korean postmenopausal women with osteoporosis (ClinicalTrials.gov identifier NCT02791516).
Antibacterial and Antifungal Properties of Composite Polyethylene Materials Reinforced with Neem and Turmeric (2020)

With the increased scientific interest in green technologies, many researches have been focused on the production of polymeric composites containing naturally occurring reinforcing particles. Apart from increasing mechanical properties, these additions can have a wide range of interesting effects, such as increasing the resistance to bacterial and fungal colonization. In this work, different amounts of two different natural products, namely neem and turmeric, have been added to polyethylene to act as a natural antibacterial and antifungal product for food packaging applications. Microscopic and spectroscopic characterization showed that fractions up to 5% of these products can be dispersed into low-molecular weight polyethylene, while higher amounts could not be properly dispersed and resulted in an inhomogeneous, fragile composite. In vitro testing conducted with Escherichia coli, Staphylococcus aureus and Candida albicans showed a reduced proliferation of pathogens when compared to the polyethylene references. In particular, turmeric, resulted to be more effective against E. coli when compared to neem, while they had similar performances against S. aureus. Against C. albicans, only neem was able to show a good antifungal behavior, at high concentrations. Tensile testing showed that the addition of reinforcing particles reduces the mechanical properties of polyethylene, and, in the case of turmeric, it is further reduced by UV irradiation.
Cortisol, serotonin and depression: All stressed out? (2002)

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Supplementary Figure 4 from Human CD59 Inhibitor Sensitizes Rituximab-Resistant Lymphoma Cells to Complement-Mediated Cytolysis (2023)

Supplementary Figure 4 from Human CD59 Inhibitor Sensitizes Rituximab-Resistant Lymphoma Cells to Complement-Mediated Cytolysis
Computer-generated holographic filters for rotationally invariant image processing (1985)

A new class of optical correlation filters has been implemented experimentally using computer-generated holographic elements. The new filters are formed from a recombination of the angular harmonics of the target image so that the target image can be identified from an infinite set of images of arbitrary position and angular orientation. The computer designed filters have a large amplitude dynamic range and rapid phase variations. Such image functions are difficult to encode in a computer-generated hologram having small quantization and binarization error as well as high diffraction efficiency. Numerical modeling has shown that the filters are robust to amplitude clipping and phase quantization. Filters are being fabricated on a high resolution vector graphics device followed by photoreduction and also on an electron beam system. Various polar and projection CGH algorithms are being compared experimentally in the optical correlation system.
WEED SCIENCE Cutleaf Eveningprimrose Control with Preplant Burndown Herbicide Combinations in Cotton (2000)

Successful elimination of vegetation prior to planting cotton (Gossypium hirsutum L.) in reduced tillage production is critical for adequate stand establishment, eliminating early-season weed interference, and maintaining yields. Cutleaf eveningprimrose (Oenothera laciniata Hill) often is prevalent in cotton fields in the spring prior to planting. Field experiments were conducted during 1995 and 1996 in Louisiana and in 1999 in North Carolina to compare cutleaf eveningprimrose control
The software maintenance project effort estimation model based on function points (2003)

Abstract In this study, software maintenance size is discussed and the software maintenance project effort estimation model (SMPEEM) is proposed. The SMPEEM uses function points to calculate the volume of the maintenance function. Ten value adjustment factors (VAF) are considered and grouped into three categories of maintenance characteristics, that is the engineer's skill (people domain), its technical characteristics (product domain) and the maintenance environment (process domain). Finally, we suggest an exponential function model which can show the relationships among the maintenance efforts, maintenance environment factors, and function points of the software maintenance project. Regression analysis of some small maintenance projects demonstrates the significance of the SMPEEM model. Copyright © 2003 John Wiley &amp; Sons, Ltd.
Efficacy of Perflubutane Microbubble-Enhanced Ultrasound in the Characterization and Detection of Focal Liver Lesions: Phase 3 Multicenter Clinical Trial (2009)

Compared with unenhanced ultrasound and dynamic CT, contrast-enhanced ultrasound with perflubutane microbubbles improved diagnostic efficacy in both characterization and detection of focal liver lesions with no serious adverse drug reactions.
Talazoparib has no clinically relevant effect on QTc interval in patients with advanced solid tumors (2019)

The aims of this study were (i) to evaluate the effect of talazoparib (1 mg once daily) on cardiac repolarization in patients with advanced solid tumors by assessing corrected QT interval (QTc) and (ii) to examine the relationship between plasma talazoparib concentration and QTc. In this open-label phase 1 study, patients had continuous 12-lead ECG recordings at baseline followed by time-matched continuous ECG recordings and collection of talazoparib plasma pharmacokinetic samples predose and at 1, 2, 4, and 6 h postdose on treatment days 1 and 22 and before talazoparib administration on day 2. ECG recordings were submitted for independent central review where triplicate 10-s ECGs, extracted up to 15 min before pharmacokinetic samples, were assessed for RR, PR, QRS, and QT intervals and ECG morphology. QT interval was corrected for heart rate using Fridericia's (QTcF) and Bazett's (QTcB) formulae. Linear mixed-effects modeling was used to examine the relationship between QTc and RR interval change from baseline and plasma talazoparib concentration. Thirty-seven patients received talazoparib. Mean change in QTcF from time-matched baseline ranged from -3.5 to 6.9 ms, with the greatest change 1 h postdose on day 22. No clinically relevant changes in PR, QRS, QTcB, QTcF, or RR intervals, heart rate, or ECG morphology were observed. No concentration-dependent effect on heart rate or QTc was observed. No deaths, permanent treatment discontinuations due to adverse events were reported. Talazoparib (1 mg once daily) had no clinically relevant effects on cardiac repolarization.
A standing wave-type noncontact linear ultrasonic motor (2001)

In this study, a novel standing wave-type noncontact linear ultrasonic motor is proposed and analyzed. This linear ultrasonic motor uses a properly controlled ultrasonic standing wave to levitate and drive a slider. A prototype of the motor was constructed by using a wedge-shaped aluminum stator, which was placed horizontally and driven by a multilayer PZT vibrator. The levitation and motion of the slider were observed. Assuming that the driving force was generated by the turbulent acoustic streaming in the boundary air layer next to the bottom surface of the slider, a theoretical model was developed. The calculated characteristics of this motor were found to agree quite well with the experimental results. Based on the experimental and theoretical results, guidelines for increasing the displacement and speed of the slider were obtained. It was found that increasing the stator vibration displacement, or decreasing the gradient of the stator vibration velocity and the weight per unit area of the slider, led to an increase of the slider displacement. It was also found that increasing the amplitude and gradient of the stator vibration velocity, or decreasing the weight per unit area of the slider and the driving frequency, gave rise to an increase of the slider speed. There exists an optimum roughness of the bottom surface of the slider at which the slider speed has a maximum.
High concentration antimony diffusion into silicon using auxiliary wafers (1981)

The behavior of auxiliary wafers used for Sb diffusion has been studied, with the auxiliary wafers set face to face with diffusion wafers. A high Sb concentration, as high as the solid solubility of Sb into silicon, was attained by auxiliary wafers lapped with alumina powder but not attained by those lapped with carborundum powder. Sapphire substrates, chemical vapor deposition-Al2O3 film deposited on silicon wafers, and Al+ -implanted silicon wafers were used for the auxiliary wafers, and they brought desirable results. Chemical analysis showed that the glass layer grown on the diffusion wafer contained aluminum oxide, which was estimated to give a high Sb concentration in the diffusion wafer.
Synthesis and Characterization of Highly Crystalline Anatase Nanowire Arrays (2004)

We developed a novel synthesis strategy of titania nanowire arrays by employing simple hydrothermal reaction and ion-exchange reaction techniques. Hydrothermal reactions of metallic titanium powder with <TEX>$H_2O_2$</TEX> in a 10 M NaOH solution produced a new sodium titanate compound, <TEX>$Na_2Ti_6O_{13}{\cdot}xH_2O$</TEX> (x~4.2), as arrays of nanowires of lengths up to 1 mm. Acid-treatment followed by calcination of this material produced arrays of highly crystalline anatase nanowires as evidenced by x-ray diffraction, Raman spectroscopy, and transmission electron microscopy studies. In both cases of sodium titanate and anatase, the nanowires have exceptionally large aspect ratios of 10,000 or higher, and they form arrays over a large area of <TEX>$1.5 {\times} 3 cm^2$</TEX>. Observations on the reaction products with varied conditions indicate that the array formation requires simultaneously controlled formation and crystal growth rates of the <TEX>$Na_2Ti_6O_{13}{\cdot}xH_2O$</TEX> phase.
Exploring the Limits of Förster Theory for Energy Transfer at a Separation of 20 Å (2009)

Cutting the corner: An excellent agreement has been obtained between experimental and computed coulombic coupling matrix elements for donor-spacer-acceptor systems, which consist of a boron dipyrromethane donor and acceptor in various stages of protonation. This correlation occurs in spite of reservations about the validity of Förster theory being applied to intramolecular electronic energy transfer (ET) over short (e.g., 20 A) distances (see picture).
EQSIM—A multidisciplinary framework for fault‐to‐structure earthquake simulations on exascale computers part I: Computational models and workflow (2020)

Computational simulations have become central to the seismic analysis and design of major infrastructure over the past several decades. Most major structures are now “proof tested” virtually through representative simulations of earthquake‐induced response. More recently, with the advancement of high‐performance computing (HPC) platforms and the associated massively parallel computational ecosystems, simulation is beginning to play a role in increased understanding and prediction of ground motions for earthquake hazard assessments. However, the computational requirements for regional‐scale geophysics‐based ground motion simulations are extreme, which has restricted the frequency resolution of direct simulations and limited the ability to perform the large number of simulations required to numerically explore the problem parametric space. In this article, recent developments toward an integrated, multidisciplinary earth science‐engineering computational framework for the regional‐scale simulation of both ground motions and resulting structural response are described with a particular emphasis on advancing simulations to frequencies relevant to engineered systems. This multidisciplinary computational development is being carried out as part of the US Department of Energy (DOE) Exascale Computing Project with the goal of achieving a computational framework poised to exploit emerging DOE exaflop computer platforms scheduled for the 2022–2023 timeframe.
Structure and Synthesis of SSZ-63:  Toward an Ordered Form of Zeolite Beta (2005)

The synthesis, characterization, and structure elucidation of the borosilicate zeolite SSZ-63 are described. SSZ-63 is synthesized using the 1-cyclodecyl-1-methylpyrrolidinium cation as a structure-directing agent. The structural model for SSZ-63 was determined by comparison of its powder X-ray diffraction pattern with those of zeolite beta and its polytype structures. Whereas conventional zeolite beta may be described as a random intergrowth of polytypes A and B, SSZ-63 is more accurately described as a random intergrowth of polytypes B and C(H) (the hypothetical polytype C proposed by Higgins). Polytype C(H) is essentially an ordered intergrowth (of polytypes A and B) in which one of the crystallographic projections is equivalent to those in polytype A and another projection is equivalent to those in polytype B. Unlike zeolite beta, which possesses significant disorder related to layer shifts along both the a- and b-crystallographic axes, the structure of SSZ-63 has little disorder associated with the translations of layers in the a-direction. DIFFaX simulations of the powder diffraction patterns, electron diffraction, and high-resolution transmission electron microsocopy data all support the proposed model.