gebhart/patrepeval huggingface dataset:
Fire Monitoring - The use of medium resolution satellites (AVHRR, MODIS, TET) for long time series processing and the implementation in User Driven Applications and Services (2015)

Abstract. This paper introduces fire monitoring works of two different projects, namely TIMELINE (TIMe Series Processing of Medium Resolution Earth Observation Data assessing Long –Term Dynamics In our Natural Environment) and PHAROS (Project on a Multi-Hazard Open Platform for Satellite Based Downstream Services). It describes the evolution from algorithm development from in applied research to the implementation in user driven applications and systems. Concerning TIMELINE, the focus of the work lies on hot spot detection. A detailed description of the choice of a suitable algorithm (round robin approach) will be given. Moreover, strengths and weaknesses of the AVHRR sensor for hot spot detection, a literature review, the study areas and the selected approach will be highlighted. The evaluation showed that the contextual algorithm performed best, and will therefore be used for final implementation. Concerning the PHAROS project, the key aspect is on the use of satellite-based information to provide valuable support to all phases of disaster management. The project focuses on developing a pre-operational sustainable service platform that integrates space-based EO (Earth Observation), terrestrial sensors and communication and navigation assets to enhance the availability of services and products following a multi-hazard approach.
Polar Ozone and Aerosol Measurement III measurements of water vapor in the upper troposphere and lowermost stratosphere (2002)

We present water vapor measurements made by the Polar Ozone and Aerosol Measurement (POAM) III instrument since May 1998 in the upper troposphere and lowermost stratosphere. While POAM III is primarily a stratospheric instrument, many of the POAM III occultation measurements allow for the retrieval of water vapor in the upper troposphere. The Measurements of Ozone and Water Vapor by Airbus In‐Service Aircraft (MOZAIC) instruments provide a large number of coincident measurements and thus offer the best opportunity to validate POAM measurements in the highly spatially variable regions of the upper troposphere‐lowermost stratosphere, where the mixing ratios are much larger than those found throughout most of the stratosphere. The comparison shows that there is no statistically significant difference in the response of the two instruments to changes in water vapor and that in the regime where the MOZAIC measurements are thought to be most accurate, the water vapor mixing ratios measured by POAM are 10% higher. The POAM III Northern Hemisphere measurements are taken from 55° to 71° and show a qualitatively reasonable seasonal variation, with high mixing ratios in the upper troposphere in the summer and low mixing ratios in the winter. Comparisons of the seasonal variations of the POAM measurements with those from the upper tropospheric Microwave Limb Sounder (MLS) measurements from the early 1990s show qualitative similarities. The ∼1 km vertical resolution of POAM measurements allows us to study in greater detail than other satellite instruments the complex variations in water vapor that occur in the upper troposphere and lowermost stratosphere. Among the interesting features observed is a rise in the level of the high‐latitude hygropause from April through September.
Preparation and Application of Nanostructured Perovskite Phases (2004)

Abstract Transition metal oxide compounds with perovskite‐type structure (AMX 3‐δ ) show besides attractive physical properties, such as high temperature superconduction or thermoelectricity, often excellent catalytic properties for various redox reactions. The catalytic reactivity is strongly dependent on composition, structure and of course the specific surface area of the compounds. Fine‐tuning of the properties can therefore be achieved by suitable cation‐ and anion‐ substitutions and by adjusting the morphology of the compounds. For systematic studies on the relationship between composition, structure and properties in these systems fine particles as well as thin films of identical compositions e.g. La 1‐x Ca x MO 3‐δ (x = 0, 0.3, 0.4 , 0.5) (M = Fe, Co, Ni, Mn, Ti) are produced with diverse “chimie douce” methods. The samples are characterised concerning their chemical and physical properties. Carbon nanotube composite materials have been produced by catalytic decomposition of gaseous carbon compounds on nanometer‐size transition metal clusters on top of perovskite‐type metal oxides and tested for a possible application as oxygen electrodes in air based batteries.
Pulse thermal energy transport/storage system (2023)

A pulse-thermal pump having a novel fluid flow wherein heat admitted to a closed system raises the pressure in a closed evaporator chamber while another interconnected evaporator chamber remains open. This creates a large pressure differential, and at a predetermined pressure the closed evaporator is opened and the opened evaporator is closed. This difference in pressure initiates fluid flow in the system.
EEG-Based Motor Imagery Classification with Deep Multi-Task Learning (2019)

In the past decade, Electroencephalogram (EEG) has been applied in many fields, such as Motor Imagery (MI) and Emotion Recognition. Traditionally, for classification tasks based on EEG, researchers would extract features from raw signals manually which is often time consuming and requires adequate domain knowledge. Besides that, features manually extracted and selected may not generalize well due to the limitation of human. Convolutional Neural Networks (CNNs) plays an important role in the wave of deep learning and achieve amazing results in many areas. One of the most attractive features of deep learning for EEG-based tasks is the end-to-end learning. Features are learned from raw signals automatically and the feature extractor and classifier are optimized simultaneously. There are some researchers applying deep learning methods to EEG analysis and achieving promising performances. However, supervised deep learning methods often require large-scale annotated dataset, which is almost impossible to acquire in EEG-based tasks. This problem limits the further improvements of deep learning models for classification based on EEG. In this paper, we propose a novel deep learning method DMTL-BCI based on Multi-Task Learning framework for EEG-based classification tasks. The proposed model consists of three modules, the representation module, the reconstruction module and the classification module. Our model is proposed to improve the classification performance with limited EEG data. Experimental results on benchmark dataset, BCI Competition IV dataset 2a, show that our proposed method outperforms the state-of-the-art method by 3.0%, which demonstrates the effectiveness of our model.
Immunoprecipitation of the parathyroid hormone receptor. (1987)

An 125I-labeled synthetic analog of bovine parathyroid hormone, [8-norleucine,18-norleucine,34-tyrosine]PTH-(1-34) amide ([Nle]PTH-(1-34)-NH2), purified by high-pressure liquid chromatography (HPLC), was employed to label the parathyroid hormone (PTH) receptor in cell lines derived from PTH target tissues: the ROS 17/2.8 rat osteosarcoma of bone and the CV1 and COS monkey kidney lines. After incubation of the radioligand with intact cultured cells, the hormone was covalently attached to receptors by using either a photoaffinity technique or chemical (affinity) cross-linking. In each case, covalent labeling was specific, as evidenced by a reduction of labeling when excess competing nonradioactive ligand was present. After covalent attachment of radioligand, membranes were prepared from the cells and solubilized in the nonionic detergent Nonidet P-40 or octyl glucoside. The soluble membrane fraction present in the supernatant of a 100,000 X g centrifugation was incubated with IgG prepared from anti-PTH antiserum generated to the amino-terminal region, residues 1-34, of PTH. The IgG-PTH-receptor complex was precipitated with staphylococcal protein A-Sepharose. Analysis of the immunoprecipitate on NaDod-SO4/polyacrylamide gel electrophoresis followed by autoradiography revealed the presence of a doublet of apparent molecular mass 69-70 kDa. Specifically labeled bands of approximate molecular mass 95 and 28 kDa were also observed. The anti-PTH IgG was affinity purified by passage over a PTH-Sepharose column and used to make an immunoaffinity column. The 70- and 28-kDa bands were also observed after labeled solubilized membrane preparations were allowed to bind to this column and then were eluted by using a [Nle]PTH-(1-34)-NH2-containing buffer or acetic acid. These studies suggest that the use of an anti-PTH antiserum that binds receptor-bound hormone is likely to be a useful step in the further physiochemical characterization and purification of the PTH receptor.
InP Photonic Integrated Circuit for 2D Optical Beam Steering (2012)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text W. Guo, P. R. A. Binetti, C. Althouse, H. P. M. M. Ambrosius, L. A. Johansson, and L. A. Coldren, "InP Photonic Integrated Circuit for 2D Optical Beam Steering," in International Photonics and Optoelectronics Meetings, OSA Technical Digest (online) (Optica Publishing Group, 2012), paper IF3B.2. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
The Future of Bronchoscopy in Diagnosing, Staging and Treatment of Lung Cancer (2006)

Bronchoscopy is a central technique in diagnosing lung cancer, but also in different therapeutic approaches. A lot of techniques are available. The most common indication for bronchoscopy is for tissue sampling and determining the extent of lung cancer. Established diagnostic techniques are forceps biopsy, aspiration or brush cytology sampling, or needle aspiration. Laser therapy, electrocautery, cryotherapy and stenting are well-described techniques for the palliation of symptoms due to airway involvement in patients with advanced stages. Newer technologies, with an established role in clinical practice, are endobronchial ultrasound, autofluorescence bronchoscopy, and electromagnetic navigation. Other technologies, such as magnification, narrow-band imaging and confocal fluorescence microendoscopy, are in development for the use within the airways.
Evolution of Acoustically Vaporized Microdroplets in Gas Embolotherapy (2012)

Acoustic vaporization dynamics of a superheated dodecafluoropentane (DDFP) microdroplet inside a microtube and the resulting bubble evolution is investigated in the present work. This work is motivated by a developmental gas embolotherapy technique that is intended to treat cancers by infarcting tumors using gas bubbles. A combined theoretical and computational approach is utilized and compared with the experiments to understand the evolution process and to estimate the resulting stress distribution associated with vaporization event. The transient bubble growth is first studied by ultra-high speed imaging and then theoretical and computational modeling is used to predict the entire bubble evolution process. The evolution process consists of three regimes: an initial linear rapid spherical growth followed by a linear compressed oval shaped growth and finally a slow asymptotic nonlinear spherical bubble growth. Although the droplets are small compared to the tube diameter, the bubble evolution is influenced by the tube wall. The final bubble radius is found to scale linearly with the initial droplet radius and is approximately five times the initial droplet radius. A short pressure pulse with amplitude almost twice as that of ambient conditions is observed. The width of this pressure pulse increases with increasing droplet size whereas the amplitude is weakly dependent. Although the rise in shear stress along the tube wall is found to be under peak physiological limits, the shear stress amplitude is found to be more prominently influenced by the initial droplet size. The role of viscous dissipation along the tube wall and ambient bulk fluid pressure is found to be significant in bubble evolution dynamics.
Higher order relationships and the Medicinal Algorithmic Combinatorial Screen (MACS) (2005)

3079 Background: Targeted therapeutics are highly promising in combination because they are both well tolerated and interact with the signals that cause cancer. We propose a direct functional screen of combinations in the lab as a complement to the molecular insight based approach. However, with each drug added to the list, the number of possible combinations rises exponentially quickly beyond the capacity of any foreseeable technology to fully screen. We propose the MACS to identify combinations otherwise impossible to be found through a simple screen alone. The foundation of MACS is a genetic algorithm. One of the requirements for MACS will be the presence of some degree of higher order relationships among combinations. This means that knowing the behavior of some combinations formed from a set of drugs enables prediction of the behavior of other combinations formed from the same drugs. However, little is known of the degree of relatedness larger combinations of anticancer agents have. We performed experiments to evaluate this. Methods: A549 cells were plated at 2000/well and incubated in 96-well plates with drug for 66 hours before being read using the WST-1 proliferative assay (Roche). The agents were LY294002, PI-3-kinase inhibitor (Tocris); Anisomycin, activator JNK/SAPK activator (Tocris), Rapamycin, cdk inhibitor (Tocris); SP600125, JNK inhibitor (Tocris), Indirubin-3’-oxime, inhibits CDKs (Tocris); Bortezomib, proteasome inhibitor (Millennium Pharms). These were combined in all 64 combinations (pairs, triplets, quads etc.) done in triplicate at the single agent IC 20 dose of each drug with the experiment repeated another day. Results: Using regression analyses, reproducible modest higher order relationships were observed. Conclusion: We have preliminary evidence that knowledge of some of the combinations is modestly predictive of others, not enough to avoid a screen but enough to make a MACS possible. Further work will entail study of additional agents, altered doses and sequences, other NSCLC cell lines and non cancerous immortalized cell lines to represent host tissue, which will be presented at the poster. Ultimately, a pilot MACS system will be constructed the parameters for which will be guided by these data. No significant financial relationships to disclose.
Site‐Specific Modification of the Anticancer and Antituberculosis Polyether Salinomycin by Biosynthetic Engineering (2014)

The complex bis-spiroacetal polyether ionophore salinomycin has been identified as a uniquely selective agent against cancer stem cells and is also strikingly effective in an animal model of latent tuberculosis. The basis for these important activities is unknown. We show here that deletion of the salE gene abolishes salinomycin production and yields two new analogues, in both of which the C18C19 cis double bond is replaced by a hydroxy group stereospecifically located at C19, but which differ from each other in the configuration of the bis-spiroacetal. These results identify SalE as a novel dehydratase and demonstrate that biosynthetic engineering can be used to redirect the reaction cascade of oxidative cyclization to yield new salinomycin analogues for use in mechanism-of-action studies.
Interrogation of birefingent fiber sensors using non-reciprocal phase modulation (2009)

A novel reflective fiber interferometer with non-reciprocal phase modulation adapted from Sagnac-type fiber interferometers is used to measure the differential optical phase shift in polarimetric fiber sensors. The sensitive part consists of two birefringent fiber sections with balanced differential group delay. A key element is a 45°-Faraday-rotator that swaps the polarization states of the orthogonal light waves after their round trip through the two fiber sections. An integrated-optic birefringent phase modulator at the detector end of the sensor introduces the non-reciprocal phase modulation. The application of the interferometer to voltage sensing is experimentally demonstrated.
Systemic Polyarteritis Nodosa as the Cause of Sudden Onset Bilateral Sensorineural Hearing Loss Following Lassa Virus Infection (2016)

Abstract : Lassa virus (LASV) causes a severe, often fatal hemorrhagic disease in endemic regions of Africa and sudden-onset sensorineural hearing loss is a consequence of infection in approximately 30 percent of recovering patients. The mechanism of hearing loss in LASV-infected patients has not been identified. Here, we show that a cynomolgus macaque experimentally infected with Lassa virus who survived the initial infection, developed bilateral sensorineural hearing loss, confirmed by brainstem auditory evoked response (BAER) analysis. Histological examination of tissues from infected primates revealed pathology consistent with systemic polyarterisis nodosa (PAN), an autoimmune disorder associated with sudden hearing loss. Serological analyses to include the presence of autoimmune disease markers support this diagnosis. Our findings point toward an autoimmune etiology for LASV-associated sudden-onset hearing loss.
Squeezing the quantum fluctuations of light (1988)

Abstract This paper is intended to be an introduction to the field of non-classical light. Starting from a pictorial discussion of the properties of the radiation field, examples for the generation and possible applications of squeezed states of the light field are given.
Role of Oxygen in Growth of Carbon Nanotubes on SiC (2006)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
Simultaneous incorporations of two anticancer drugs into DNA. The structures of formaldehyde-cross-linked adducts of daunorubicin-d(CG(araC)GCG) and doxorubicin-d(CA(araC)GTG) complexes at high resolution (1993)

Anthracycline antibiotics (notably daunorubicin (DAU) and doxorubicin (DOX)) and nucleoside analog arabinosylcytosine (araC or aC) are important anticancer drugs. They are sometimes used together in the treatment of certain cancers. Both classes of compounds act by blocking DNA replication and transcription. To probe whether both drugs can be incorporated simultaneously into DNA and the possible structural consequences, we carried out x-ray diffraction analyses of the complexes between DAU/DOX and araC-containing DNA hexamers cross-linked with formaldehyde. The crystal structures were determined to high resolution (DAU-CGaCGCG, 1.2 A, space group P4(1)2(1)2, R = 0.182, 3275 reflections; DOX-CAaCGTG, 1.5 A, space group C2, R = 0.175, 3359 reflections), and they are similar to those of the previously studied DAU- and DOX-DNA complexes, despite different crystal packings. Two DAU/DOX molecules intercalate at both ends of the helix with their amino sugars in the minor groove. As in the structure of DAU-CGCGCG (Wang, A.H.-J., Gao, Y.-G., Liaw, Y.-C., and Li, Y.K. (1991) Biochemistry 30, 3812-3815), a covalent methylene bridge (from formaldehyde) between the N3' of daunosamine and the N2 of the guanine is formed in both adducts. In DOX-CAaCGTG, the two halves are slightly different with a root-mean-square deviation of 0.322 A between them. The O14 hydroxyls of the intercalated DOXs are within hydrogen bond distances to the O2P atoms of the A2p(aC3) and A8p(AC9) steps. The O2'-hydroxyl group from araC does not affect the binding of DAU-DOX or the conformation of the drug-DNA complexes. The results suggest that three major drug modifications on DNA, i.e., intercalation, covalent bond formation, and nucleoside analog incorporation, can coexist in the same DNA molecule without difficulty. When they occur in close proximity in DNA, they may provide an additive inhibitory effect for the target enzymes.
(Z)-Sarcodictyin A, a New Highly Cytotoxic Diterpenoid from the Soft Coral Bellonella albiflora (2003)

A new cytotoxic diterpene, (Z)-sarcodictyin A, was isolated from the Japanese soft coral Bellonella albiflora.(1) Its structure was elucidated on the basis of 1D and 2D NMR analysis and chemical degradation. (Z)-Sarcodictyin A showed strong cytotoxicity against HeLa human cervix cells.
Exposure and Nontarget Effects of TransgenicBtCorn Debris in Streams (2010)

Corn (Zea mays L.) transformed with a gene from the bacterium Bacillus thuringiensis (Bt) comprises 49% of all corn in the United States. The input of senesced corn tissue expressing the Bt gene may impact stream-inhabiting invertebrates that process plant debris, especially trichopteran species related to the target group of lepidopteran pests. Our goal was to assess risk associated with transgenic corn debris entering streams. First, we show the input of corn tissue after harvest was extended over months in a stream. Second, using laboratory bioassays based on European corn borer [Ostrinia nubilalis (Hübner)], we found no bioactivity of Cry1Ab protein in senesced corn tissue after 2 wk of exposure to terrestrial or aquatic environments. Third, we show that Bt near-isolines modify growth and survivorship of some species of invertebrates. Of the four nontarget invertebrate species fed Bt near-isolines, growth of two closely related trichopterans was not negatively affected, whereas a tipulid crane fly exhibited reduced growth rates, and an isopod exhibited reduced growth and survivorship on the Cry1Ab near-isoline but not on the stacked Cry1Ab + Cry3Bb1 near-isoline. Because of lack of evidence of bioactivity of Bt after 2 wk and because of lack of nontarget effects on the stacked near-isoline, we suggest that tissue-mediated differences, and not the presence of the Cry1Ab protein, caused the different responses among the species. Overall, our results provide evidence that adverse effects to aquatic nontarget shredders involve complex interactions arising from plant genetics and environment that cannot be ascribed to the presence of Cry1Ab proteins.
Pb-free Sn-Ag-Cu ternary eutectic solder (2023)

A Pb-free solder includes a ternary eutectic composition consisting essentially of about 93.6 weight % Sn-about 4.7 weight % Ag-about 1.7 weight % Cu having a eutectic melting temperature of about 217.degree. C. and variants of the ternary composition wherein the relative concentrations of Sn, Ag, and Cu deviate from the ternary eutectic composition to provide a controlled melting temperature range (liquid-solid "mushy" zone) relative to the eutectic melting temperature (e.g. up to 15.degree. C. above the eutectic melting temperature).
Medullary projections to the vagus nerve and posterolateral hypothalamus (1995)

Because of the spatial proximity existing between medullovagal and medullohypothalamic neurons, it is suggested that functional interrelationships may exist between these two neuronal populations. Specifically, it is suggested that the medullohypothalamic neurons identified in this study may support vagal-related functions by providing feedback cues to the posterolateral hypothalamus.