gebhart/patrepeval huggingface dataset:
Blood biomarker discovery in drug-free schizophrenia: the contribution of proteomics and multiplex immunoassays (2016)

Recent evidence supports an association between systemic abnormalities and the pathology of psychotic disorders which has led to the search for peripheral blood-based biomarkers. Areas covered: Here, we summarize blood biomarker findings in schizophrenia from the literature identified by two methods currently driving biomarker discovery in the human proteome; mass spectrometry and multiplex immunoassay. From a total of 14 studies in the serum or plasma of drug-free schizophrenia patients; 47 proteins were found to be significantly altered twice or more, in the same direction. Pathway analysis was performed on these proteins, and the resulting pathways discussed in relation to schizophrenia pathology. Future directions are also discussed, with particular emphasis on the potential for high-throughput validation techniques such as data-independent analysis for confirmation of biomarker candidates. Expert commentary: We present promising findings that point to a convergence of pathophysiological mechanisms in schizophrenia that involve the acute-phase response, glucocorticoid receptor signalling, coagulation, and lipid and glucose metabolism.
International Comparison of Impact Verification Programs (2000)

A horizontal comparison is made between the four laboratories that certify Charpy impact verification specimens. The participants in this study were Japan (NRLM), France (LNE), the European Commission (IRMM), and the United States (NIST). The exercise was conducted to show how the impact verification programs, specimens, and test procedures compare with each other. Results for both 8 and 2 mm strikers were compared. The study showed the following: (1) The certified energies of impact verification specimens distributed by these four metrological authorities often agreed within 1% of the average values determined in this study; (2) the variation in energy for the specimens was low, typically bracketed by a coefficient of variation of between 0.02 and 0.04; and (3) the energies measured for the tests performed with 2 and 8 mm strikers on the 4340 steel specimens were nearly equivalent, but a trend of slightly higher energy for the 2 mm tests is indicated.
Solid-gas critical flow (1985)

Maximum solid-gas transport rates have been computed using several hydrodynamic models. In the limit of zero gas density, the critical velocity equals the square root of a compressibility modulus of the powder divided by its density. Compressibility waves move with this velocity through the powder. Part II of this paper deals with homogeneous critical powder flow for which a useful expression for maximum flow has been derived and compared to an experiment from the literature.
An electronic structural model for the emitting MLCT excited states of Ru(bpy)32+ and Os(bpy)32+ (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAn electronic structural model for the emitting MLCT excited states of Ru(bpy)32+ and Os(bpy)32+Edward M. Kober and Thomas J. MeyerCite this: Inorg. Chem. 1984, 23, 24, 3877–3886Publication Date (Print):November 1, 1984Publication History Published online1 May 2002Published inissue 1 November 1984https://pubs.acs.org/doi/10.1021/ic00192a009https://doi.org/10.1021/ic00192a009research-articleACS PublicationsRequest reuse permissionsArticle Views982Altmetric-Citations130LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
RF and Optical Hybrid LEO Communication System for Non-Terrestrial Network (2022)

Small satellite LEO constellations are expected to play an important role in NTN (Non-Terrestrial Network) which expands communication service areas in three-dimensions (from sea to sky and space) in the age of Beyond 5G / 6G. To build fast and stable communication infrastructure for NTN over LEO constellations, hybrid operation of RF and optical communications is important. The authors (Axelspace, The University of Tokyo, Tokyo Institute of Technology and KIYOHARA OPTICS) have started 4-year development program on these technologies under NICT Beyond 5G R&#x0026;D promotion project. In this paper, target, scope and technical challenges of this R&#x0026;D project are introduced.
Generation and Transplantation of an Autologous Vascularized Bioartificial Human Tissue (2009)

The feasibility to bioengineer a human tissue with an innate vascularization has been shown in vitro and the clinical setting. These results may open the door for the clinical application of various sophisticated bioartificial tissue substitutes and organ replacements.
Experimental validation of Angular Quasi-Phase-Matching (2009)

We validate the theory of angular quasi-phase-matching by performing second harmonic generation and difference frequency generation in a 3.9-mm-diameter sphere cut in a 5%MgO:PPLN crystal and pumped with a tunable laser source.
T cell necessity in the pathogenesis of experimental autoimmune encephalomyelitis in mice (1976)

Cellular transfer of experimental autoimmune encephalomyelitis (EAE) was effected in mice with lymph node and spleen cells from appropriately immunized donors. In contrast to lymphoid cells, immune serum did not transfer this autoimmune disease nor did serum have any facilitating or inhibitory effect on the capacity of lymphoid cells to transfer EAE. Transfer of EAE was effected in normal mice, lightly irradiated (350 rad) and lethally irradiated (850 rad) and bone marrow-protected mice, but not in mice which had been given 850 rad total-body irradiation. There was a striking augmentation of severity of transferred EAE in the lightly irradiated recipients, possibly attributable to selective radiosensitivity of suppressor T cells. Cell-mediated immunity but not circulating antibody to basic protein of myelin was demonstrated in recipients with transferred EAE. The immune lymphoid cells responsible for transfer of EAE were T lymphocytes. Thus transfer was successful after passage of sensitized cells through anti-immunoglobulin columns and was abrogated following treatment with anti-Thy-1 serum and complement. Neonatally thymectomized mice failed to develop either EAE, cell mediated immunity or humoral antibody against myelin basic protein (BPM). Inhibition of EAE and immune responsiveness was solely due to the removal of the source of thymus lymphocytes, because reconstitution of neonatally thymectomized mice with T lymphocytes completely restored these functions. It is concluded that T lymphocytes are required for the production and adoptive transfer of EAE, for the development of cell-mediated immunity to BPM and for the production of antibody to BPM.
The Tau Parallel Performance System (2006)

The ability of performance technology to keep pace with the growing complexity of parallel and distributed systems depends on robust performance frameworks that can at once provide system-specific performance capabilities and support high-level performance problem solving. Flexibility and portability in empirical methods and processes are influenced primarily by the strategies available for instrmentation and measurement, and how effectively they are integrated and composed. This paper presents the TAU (Tuning and Analysis Utilities) parallel performance sytem and describe how it addresses diverse requirements for performance observation and analysis.
Supplementary Figure 3 from A Human Single-Domain Antibody Elicits Potent Antitumor Activity by Targeting an Epitope in Mesothelin Close to the Cancer Cell Surface (2023)

&lt;p&gt;PDF file - 1884K, CDC analysis of HN1(scFv)-hFc and SDS-PAGE analysis of molecular weight discrepancy of human antibodies.&lt;/p&gt;
Evidence and modeling of paired ions and other loss mechanisms in erbium-doped silica fibers (1993)

To explain the sub-optimal performance of erbium-doped resonant fiber lasers and superfluorescent fiber sources observed experimentally, the effects of potential loss mechanisms are explored via computer simulations. Pump excited-state absorption (ESA) at 980 nm and 1.48 micrometers , and signal ESA are unable to explain the dependence of the observed effects on concentration. Cooperative upconversion among uniformly distributed erbium ions fails to explain the observed reduction in source slope efficiency with increasing concentration. On the other hand, rapid cross-relaxation between paired ions, which might form in high concentration fibers, can produce the observed dependences. Rate equations for paired ions are used to understand their saturation behavior and their effect on the slope and threshold of fiber sources. Methods to assess the fraction of paired ions are discussed. Measurements suggest that about 18% of the ions in an aluminum co-doped silica fiber with 5 X 10<SUP>19</SUP> Er<SUP>3+</SUP>/cm<SUP>3</SUP> are paired. The effects of paired ions on the gain of Er-doped fiber amplifiers are also briefly discussed.
Увеличение эффективности органических солнечных элементов с помощью просветляющих покрытий на основе фторидных композиций (2018)

AbstractResults are presented obtained in measurements of current–voltage characteristics of organic solar cells with and without antiref lection coatings produced by melting in a solar furnace of 95 : 5 and 55 : 45 wt % MgF_2 and CaF_2 fluoride mixtures. The relative increase in the efficiency of the organic solar cells was 3.2% in the first case and 3.3% in the second.
Menopause increases the iron storage protein ferritin in skin. (2013)

Menstruation and desquamation are important routes for humans to excrete iron. Because menstruation is no longer available in postmenopausal women, in the present study, we examined whether iron accumulates more in postmenopausal skin than in premenopausal skin. Skin biopsy samples were obtained from six pre- and six postmenopausal Caucasian women. Iron levels in the form of ferritin were 42% higher, but vascular endothelial growth factor and total antioxidant capacity were 45% and 34% lower in postmenopausal skin (58.8 ± 1.3 years old) than in premenopausal skin (41.6 ± 1.7 years old), respectively. Moreover, in vitro cultured normal human epidermal keratinocytes had surprisingly high levels of ferritin when compared to immortalized human breast epithelial MCF-10A cells or human liver HepG2 cancer cells. Our results indicate that skin is a cellular repository of iron and that menopause increases iron in skin and, thus, may contribute to the manifestation of accelerated skin aging and photo aging after menopause.
Optimizing Power Density and Efficiency of a Double-Halbach Permanent-Magnet Ironless Axial Flux Motor (2016)

NASA Glenn Research Center is investigating hybrid electric and turboelectric propulsion concepts for future aircraft to reduce fuel burn, emissions, and noise. Systems studies show that the weight and efficiency of the electric system components need to be improved for this concept to be feasible. This effort aims to identify design parameters that affect power density and efficiency for a double-Halbach array permanent-magnet ironless axial flux motor configuration. These parameters include both geometrical and higher-order parameters, including pole count, rotor speed, current density, and geometries of the magnets, windings, and air gap.
Genome-wide patterns of population structure and association mapping of nut-related traits in Persian walnut populations from Iran using the Axiom J. regia 700K SNP array (2019)

Persian plateau (including Iran) is considered as one of the primary centers of origin of walnut. Sampling walnut trees originating from this arena and exploiting the capabilities of next-generation sequencing (NGS) can provide new insights into the degree of genetic variation across the walnut genome. The present study aimed to explore the population structure and genomic variation of an Iranian collection of Persian walnut (Juglans regia L.) and identify loci underlying the variation in nut and kernel related traits using the new Axiom J. regia 700K SNP genotyping array. We genotyped a diversity panel including 95 walnut genotypes from eight Iranian provinces with a variety of climate zones. A majority of the SNPs (323,273, 53.03%) fell into the "Poly High Resolution" class of polymorphisms, which includes the highest quality variants. Genetic structure assessment, using several approaches, divided the Iranian walnut panel into four principal clusters, reflecting their geographic partitioning. We observed high genetic variation across all of the populations (H<sub>O</sub> = 0.34 and H<sub>E</sub> = 0.38). The overall level of genetic differentiation among populations was moderate (F<sub>ST</sub> = 0.07). However, the Semnan population showed high divergence from the other Iranian populations (on average F<sub>ST</sub> = 0.12), most likely due to its geographical isolation. Based on parentage analysis, the level of relatedness was very low among the Iranian walnuts examined, reflecting the geographical distance between the Iranian provinces considered in our study. Finally, we performed a genome-wide association study (GWAS), identifying 55 SNPs significantly associated with nut and kernel-related traits. In conclusion, by applying the novel Axiom J. regia 700K SNP array we uncovered new unexplored genetic diversity and identified significant marker-trait associations for nut-related traits in Persian walnut that will be useful for future breeding programs in Iran and other countries.
Polling based media access protocols for use with smart adaptive array antennas (2002)

The use of an adaptive antenna array at each base station of a wireless network can provide substantial immunity to the effects of multipath fading and co-channel interference. Among the expected benefits are higher data rates, greater frequency re-use factor, and, overall, higher capacity systems as needed to enable wireless multimedia services. Media access control (MAC) protocols which facilitate the deployment of such an array have been previously proposed and studied. These MAC protocols invoke the delivery of a pilot tone from each packet access unit in the network as needed, so that the array antenna at the associated base station may rapidly adjust its weighting coefficients, thereby ensuring subsequent reliable communication between the access unit and the base station. This paper considers two modifications to these earlier protocols with the intent of improving the utilization efficiency and mean delay performance. A more general traffic model is considered and reasonable approximations are invoked to study the performance of the modified protocol. It is shown that with the proposed modifications, a maximum link utilization efficiency of about 97% is readily achieved. Further, it is shown that this maximum utilization efficiency is independent of the number of remote users in the network. The modifications also help in achieving a considerable reduction in the average delay in low load regimes. For typical system parameters, results show that at very low loads, the average delay is only about 10% of the average delay experienced when the old protocol is used.
ANÁLISIS DE PROBLEMAS ELÁSTICOS 2D UTILIZANDO LA TÉCNICA DE DESCOMPOSICIÓN DE DOMINIO PARALELO-ITERATIVA Y EL MÉTODO DE LOS ELEMENTOS DE CONTORNO / Analysis of 2D Elastic Problems by using a Parallel-Iterative Domain Decomposition Technique and the Bounda (2013)

Para resolver problemas de elasticidad con el Metodo de Elementos de Contorno (MEC) solo se requiere discretizar lasuperficie; sin embargo las matrices resultantes se caracterizan por no ser diagonalmente dominantes y estar completamentellenas. Esto representa un reto para resolver problemas de gran escala, dado los requerimientos de almacenamiento dedatos y la solucion de sistemas de gran numero de ecuaciones. En este articulo se desarrolla una tecnica de descomposicionde dominio o multiregiones eficiente y efectiva, con algoritmos iterativos region por region, ensamblados especialmentepara paralelismo computacional. La aproximacion de descomposicion de dominio efectivamente reduce el numero decondiciones de los sistemas de ecuaciones algebraicas resultantes, al mismo tiempo que incrementa la eficiencia de losprocesos de solucion, convergiendo rapidamente a una solucion estable. El paralelismo computacional satisfaceperfectamente la tecnica iterativa de la descomposicion de dominio. Los resultados demuestran la calidad de la aproximacional comparar con las soluciones de problemas en una region y las respectivas soluciones analiticas. ABSTRACT The Boundary Element Method (BEM) requires only a surface mesh to solve elasticity problems; however, the resultingmatrices are fully-populated and non-diagonally dominant. This poses serious challenges for large-scale problems due tostorage requirements and the solution of large sets of non-symmetric systems of equations. In this article, an effective andefficient domain decomposition, or artificial sub-sectioning technique, along with a region-by-region iteration algorithmparticularly tailored for parallel computation to address these issues is developed. The domain decomposition approacheffectively reduces the condition numbers of the resulting algebraic systems, while increasing efficiency of the solutionprocess and decreasing memory requirements. The iterative process converges very efficiently while offering substantialsavings in memory. The iterative domain decomposition technique is ideally suited for parallel computation. Resultsdemonstrate the validity of the approach by providing solutions that compare closely to single-region BEM solutions andbenchmark analytical solutions.Keywords: domain decomposition, elasticity, boundary element method, parallel computation.
Effect of ionic strength on the size-exclusion chromatography of aqueous polystyrene latices (1984)

Purified polystyrene latices with narrow particle-size distributions have been prepared and studied by size-exclusion chromatography (s.e.c.) with columns packed with porous glass beads. Mean elution volumes and peak widths are found to increase as the ionic strength, I, of the eluant is increased. This can be interpreted quantitatively in terms of an effective exclusion radius of a latex particle which includes a contribution from the electrical double layers that is proportional to I–½.
Fault diagnosis using recursive least square algorithm for permanent magnet synchronous motor drives (2011)

This paper proposes a novel diagnosis scheme using parameter estimation of stator resistance, especially, in subject to the open-phase faults of PMSM drives. The stator resistances of PMSM are estimated by recursive least square (RLS) algorithm in real time. The fault diagnosis is achieved by analyzing the estimated stator resistance of each phase according to fault condition. The proposed diagnosis scheme is implemented without any extra devices. Moreover, the estimated parameter information can be used in order to improve the control performance. The feasibility of the proposed fault diagnosis scheme is proved by simulation and experimental results.
Carbonylation at sp3 C−H Bonds Adjacent to a Nitrogen Atom in Alkylamines Catalyzed by Rhodium Complexes (2000)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTCarbonylation at sp3 C−H Bonds Adjacent to a Nitrogen Atom in Alkylamines Catalyzed by Rhodium ComplexesNaoto Chatani, Taku Asaumi, Tsutomu Ikeda, Shuhei Yorimitsu, Yutaka Ishii, Fumitoshi Kakiuchi, and Shinji MuraiView Author Information Department of Applied Chemistry Faculty of Engineering, Osaka University Suita, Osaka 565-0871, Japan Cite this: J. Am. Chem. Soc. 2000, 122, 51, 12882–12883Publication Date (Web):December 27, 2000Publication History Received13 July 2000Published online27 December 2000Published inissue 1 December 2000https://pubs.acs.org/doi/10.1021/ja002561whttps://doi.org/10.1021/ja002561wrapid-communicationACS PublicationsCopyright © 2000 American Chemical SocietyRequest reuse permissionsArticle Views4410Altmetric-Citations182LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Bond cleavage,Carbonylation,Hydrocarbons,Nitrogen,Pyridines Get e-Alerts
Shaping Up Adaptive Immunity: The Impact of CCR7 and CXCR5 on Lymphocyte Trafficking (2003)

The effective onset of adaptive immune responses requires that naïve antigen-specific lymphocytes, being inherently rare throughout the body, rapidly encounter foreign antigens. This problem has been elegantly solved in evolution by inventing secondary lymphoid tissues as intersections in the migratory pathway of antigen-presenting dendritic cells and antigen-specific lymphocytes. Chemokines play a central role in guiding cell movements in the course of immune responses and in lymphoid system homeostasis. In particular, the chemokine receptors CCR7 and CXCR5 are key molecules for the entry of lymphocytes and dendritic cells into secondary lymphoid organs and their homing to T-cell and B-cell zones therein. CCR7 and CXCR5 are differentially expressed on the cell surface of lymphocytes and dendritic cells depending of the stage of cellular differentiation and activation, thus allowing these cells to change their homing capacity and prospective traffic routes.
Maneuvering Chair Transformable to Nursing Care Bed (2018)

In this paper, we describe a maneuvering chair transformable to a nursing care bed. Most of the caregivers suffer from their lower back pains caused by transferring care-receivers at care beds. In order to reduce the physical burdens of caregivers, we have developed an autonomous chair maneuvered by care-receivers. This chair is able to transfer a care-receiver from a bed without caregiver burden such as holding up the care-receiver. Moreover, the care-receiver can also manipulate the chair as an electric wheelchair. In particular, the joystick controller and the velocity profile of the chair are carefully designed. We propose the concept of the maneuvering chair system, and experimentally evaluate the ride quality of the chair.