gebhart/patrepeval huggingface dataset:
A case for grid computing on virtual machines (2004)

We advocate a novel approach to grid computing that is based on a combination of "classic" operating system level virtual machines (VMs) and middleware mechanisms to manage VMs in a distributed environment. The abstraction is that of dynamically instantiated and mobile VMs that are a combination of traditional OS processes (the VM monitors) and files (the VM state). We give qualitative arguments that justify our approach in terms of security, isolation, customization, legacy support and resource control, and we show quantitative results that demonstrate the feasibility of our approach front a performance perspective. Finally, we describe the middleware challenges implied by the approach and an architecture for grid computing using virtual machines.
Prevalence of depression in cancer patients: a meta‐analysis of diagnostic interviews and self‐report instruments (2013)

Pooled mean prevalence of depression in cancer patients ranged from 8% to 24% and differed by the type of instrument, type of cancer and treatment phase. Future prospective studies should disentangle whether differences in prevalence of depression are caused by differences in the type of instrument, type of cancer or treatment phase. © 2013 The Authors. Psycho-Oncology published by John Wiley & Sons, Ltd.
Effect of Carbon Dioxide in Seawater on Desalination: A Comprehensive Review (2006)

Abstract The two main methods of removing salt from ocean water currently in use for large scale applications are: distillation using thermal desalination and membrane reverse osmosis separation. A detailed knowledge of the CO2 solubility in the seawater at the conditions prevailing in the system is required for the modeling of CO2 release in the multi‐stage flash distillers. The measurement of the solubility of CO2 in pure water has been extensively studied in the literature, whereas there is a lack of saline solutions studies. Several studies have investigated the solubility of CO2 in seawater under different temperatures and pressures without covering the conditions that prevailed in the desalination plants for example low pressures and high temperatures. The gas solubility can be theoretically estimated by considering the ionic strength and the salting‐out parameter in the low‐pressure regime, i.e., near atmospheric pressure. The measurements of gas solubility can be made as a function of the seawater temperature and salinity at low pressure where effect of pressure can be considered negligible. Alkaline scale formation causes fouling in the MSF plants and it is known that the rate of formation of calcium carbonate and magnesium hydroxide in seawater depends on a number of parameters such as temperature, pH, concentration of bicarbonate ions, rate of CO2 release, concentration of Ca2+ and Mg2+ ions, and total dissolved solids. This review shows an overview of the carbon dioxide solubility in the high concentrated saline water, carbonate equilibriums in the seawater and the various correlations used to characterize the CO2‐seawater system.
Immunohistochemical Analysis of Regulatory T Cell Markers FOXP3 and GITR on CD4+CD25+ T Cells in Normal Skin and Inflammatory Dermatoses (2007)

Regulatory T cells (Treg) are a subset of T lymphocytes that play a central role in immunologic tolerance and in the termination of immune responses. The identification of these cells in normal and inflammatory conditions may contribute to a better understanding of underlying pathology. We investigated the expression of FOXP3 and GITR in normal skin and in a panel of different inflammatory dermatoses. Immunohistochemical double stainings in skin tissue sections revealed that FOXP3 and GITR were almost exclusively present on T cells that express both CD4 and CD25. Further, immunohistochemical double staining, as well as fluorescence-activated cell sorter analysis, on peripheral blood T cells showed that most FOXP3(+) cells expressed GITR and vice versa, whereas a minority were single-positive for these markers. The mean frequency of FOXP3(+) T cells in spongiotic dermatitis, psoriasis, and lichen planus was in the same range (25-29%), but the frequency of these cells in leishmaniasis appeared to be lower (approximately 15%), although this was not statistically significant. The mean frequency of GITR(+) T cells was fairly similar in all conditions studied (14-20%). Normal human skin also contained FOXP3(+) and GITR(+) cells in the same frequency range as in diseased skin, but the absolute numbers were, of course, much lower. In conclusion, frequencies of FOXP3(+) and GITR(+) T cells were similar in all inflammatory skin diseases studied and normal skin, despite the well-known differences among the inflammatory conditions under investigation.
Avaliação do nível de conhecimento de acadêmicos de Odontologia sobre fotopolimerização (2021)

O sucesso clínico de materiais resinosos é dependente de uma adequada polimerização. Diversos materiais fotoativados são utilizados frequentemente nas clínicas-escola de Odontologia. O objetivo desse estudo foi avaliar o nível de conhecimento dos acadêmicos do 10º período de Odontologia do Centro Universitário Maurício de Nassau, Recife/PE, sobre fotopolimerização, por meio de questionário. Os dados foram tabulados e analisados por meio de estatísticas descritivas, teste Qui-quadrado de Pearson e teste Exato de Fischer, com nível de significância de 5% (p&lt;0,05). Os resultados demonstram que 83,8% dos estudantes não possuem fotopolimerizador, 72,9% não conhecem a potência do aparelho, 56,2% não sabem qual é a potência mínima ideal e apenas 8,5% sabem o nome do aparelho aferidor da irradiância / potência. Além disso, 48,5% não sabem o comprimento de onda ideal para fotoativação de resina composta e 69,2% desconhecem o tipo de aparelho que utilizam (monowave ou poliwave). Em relação ao tempo de fotopolimerização, 60,8% afirmaram utilizar 20 segundos em resinas compostas convencionais e 38,5% utilizam por 40 segundos em resinas compostas Bulk-fill. Embora 84,6% afirmem usar aparelhos fotopolimerizadores frequentemente, apenas 26,9% sabem a distância ideal da ponteira à restauração. Além disso, 51,5% relataram que fazem a limpeza e desinfecção com álcool 70GL e 45,4% usam barreira plástica. Nesse contexto, pode-se concluir que o nível do conhecimento dos acadêmicos em relação à fotopolimerização foi insatisfatório, exigindo uma abordagem e avaliação mais efetivas para que os discentes tenham consciência da importância clínica deste procedimento e suas consequências.
[Cerebral and renal aspergillosis in a patient with orthotopic heart transplant: diagnosis, treatment and follow-up]. (1989)

A cardiac transplant recipient developed systemic aspergillosis with abscesses from aspergillus fumigatus in the brain and the right kidney. Surgical resections were performed (lobectomy for the brain abscess, partial resection for the renal abscess followed, after extension of the infection, by right nephrectomy) combined with therapy with itraconazole, a new antimycotic agent. Recovery from the infection was obtained and at 18 months of follow-up the patient feels well without signs of recurrences of the infection.
Formation of Crystallographic Orientation of Bone Apatite Crystallites Investigated by Powder-Metallurgical Method and Development of Novel Bone Implant Focusing on Apatite Orientation (2015)

The preferential orientation and its degree of crystallographic c-axis of biological apatite powder particles dominates bone mechanical function. Based on the importance of the apatite orientation, we are trying to elucidate the mechanisms through which the anisotropic apatite micro-arrangement forms using the regenerated bones and pathological bones including gene-modified ones. Of the many factors that possibly affect apatite orientation, in vivo stress field was found to play a significant role, therefore, applying a sound stress field onto bones is essential to induce a healthy bones that have optimally anisotropic apatite arrangement. From this perspective, bone implants should be developed targeting on the formation and maintenance of healthy apatite orientation and aggressive stress control. Anisotropic porous structure might be a promising strategy to create such implants with the novel concepts. Layer-by-layer additive manufacturing technology that fabricates products with arbitrary shape and inner structure from powdered metal materials is a powerful tool to achieve anisotropically-structured implants for inducing apatite orientation. Our research and development, clarifying bones’ functionalization mechanisms and creating highly-functionalized implants, both of which are closely connected with each other, are ongoing by utilizing powder metallurgy and biology.
Renal cell carcinoma with an Xp11.2 translocation in a 16-year-old girl: A case report with cytological features (2006)

We report a case of a 16-year-old girl with a left renal tumor discovered by her family practitioner. On physical examination the patient had a painless abdominal mass, located in the upper medium portion of the abdomen on the left side with a voussure of the abdominal wall. Ultrasound and abdominal pelvic CAT scan revealed a large heterogeneous mass with calcifications in the inferior portion of the left kidney. We made touch-imprint cytological preparations of the biopsy fragments, obtained under ultrasound guidance. Cytological analysis revealed highly cellular smears with malignant cells arranged in large clusters or rarely isolated, sometimes surrounding hyaline nodules with numerous psammoma bodies. After May-Grünwald-Giemsa staining, cells displayed moderately irregular nuclei with an abundant and pale basophilic cytoplasm with well-defined borders and a finely granular texture. The diagnosis of a special type of renal cell carcinoma was suspected, and was then confirmed after examination of the biopsy sample and the corresponding surgical specimen. The histomorphologic features were those of a renal cell carcinoma associated with an Xp11.2 translocation. Immunohistochemistry revealed this translocation by showing nuclear positivity in tumor cells for an antibody raised against the TFE3 protein. The clinical outcome was marked several months later by metastases in lymph nodes, bone, lung, and adrenal gland as well as a local recurrence.
Enhancement of silicon nanocrystals luminescence by plasmonic structures for photovoltaic application (2012)

Get PDF Email Share Share with Facebook Share on X Post on reddit Share with LinkedIn Add to Mendeley Add to BibSonomy Share with WeChat Get Citation Copy Citation Text J. Goffard, D. Gérard, P. Miska, A. Baudrion, M. Vergnat, and J. Plain, "Enhancement of silicon nanocrystals luminescence by plasmonic structures for photovoltaic application," in Renewable Energy and the Environment Optics and Photonics Congress, OSA Technical Digest (online) (Optica Publishing Group, 2012), paper PW2B.5. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Flexible Robotics : Applications to Multiscale Manipulations. (2013)

International audience
End-Users Get Maneuvered: Empirical Analysis of Redirection Hijacking in Content Delivery Networks (2018)

The success of Content Delivery Networks (CDNs) relies on the mapping system that leverages dynamically generated DNS records to distribute client’s request to a proximal server for achieving optimal content delivery. However, the mapping system is vulnerable to malicious hijacks, as (1) it is very difficult to provide pre-computed DNSSEC signatures for dynamically generated records and (2) even considering DNSSEC enabled, DNSSEC itself is vulnerable to replay attacks. By leveraging crafted but legitimate mapping between end-user and edge server, adversaries can hijack CDN’s request redirection and nullify the benefits offered by CDNs, such as proximal access, load balancing, and DoS protection, while remaining undetectable by existing security practices. In this paper, we investigate the security implications of dynamic mapping that remain understudied in security and CDN community. We perform a characterization of CDN’s service delivery and assess this fundamental vulnerability in DNS-based CDNs in the wild. We demonstrate that DNSSEC is ineffective to address this problem, even with the newly adopted ECDSA that is capable of achieving live signing. We then discuss practical countermeasures against such manipulation.
Facile and General Preparation of Multifunctional Main-Chain Cationic Polymers through Application of Robust, Efficient, and Orthogonal Click Chemistries (2012)

Poly(ß-hydroxyl amine)s are prepared from readily available small molecular building blocks at ambient conditions. These macromolecules can be transformed into main-chain cationic polymers upon quaternization of the backbone amine units. The modular and mild nature of the synthesis allows for incorporation of multiple (2-4) chemically distinct reactive sites in the polymer chain. Modifications of the reactive sites afford multifunctional polymers with tunable properties. The orthogonal nature of the involved chemistries sets the synthetic pathway free from any functional group protection/deprotection requirements. This feature also allows for alteration of the modification sequence.
Perspectives in the therapeutic use of leptin (2001)

The cloning and characterisation of the protein encoded by the ob gene, called leptin, has represented an enormous advance in the knowledge we have at the present time on the control of appetite and the regulation of body weight. Animal experiments have shown that this adipocyte-derived hormone informs the hypothalamus about the magnitude of fat stores and induces changes in eating behaviour and thermogenesis directed to maintain nutritional homeostasis. Besides the CNS and adipose tissue, other tissues like the gonads, adrenals, pancreas, blood vessels, immune cells and bone are also targets for leptin action, setting the basis for the pleiotropic character of leptin. In contrast to ob(-)/ob(-) mice, which have leptin deficiency, obese patients usually exhibit hyperleptinaemia due to leptin resistance of uncertain aetiology. Patients with congenital leptin deficiency show a dramatic response to recombinant leptin therapy in terms of body weight and fat reduction. However, in contrast to animals, no thermogenic effect has been demonstrated in humans treated with leptin. Leptin-resistant obese subjects display a heterogeneous response to leptin treatment, though some patients achieve a significant weight loss when receiving high doses. New formulations are being tried with different success rates. Before leptin can play a role in the treatment of obesity, more studies are needed to discover which is the adequate dose, which the best route and form of administration and how we can select the patients who will benefit from this particular therapy. The development of new leptin analogues with high penetrating capacity to cross the blood-brain barrier and the investigation of other approaches to overcome the leptin resistance are awaited. Future applications of leptin may be directed to the treatment of infertility, wound healing and bone remodelling among others.
Operando Gassing Studies of All-Solid-State Battery Cells (2020)

All-solid-state batteries (SSBs) are considered as next-generation energy storage technology with the possibility of higher energy and power densities as well as safety compared to conventional lithium-ion batteries [1]. SSBs with sulfidic solid electrolytes (SEs) as a component are thought to be the closest towards practical implementation [2] despite widely reported side reactions at the cathode active material (CAM)/SE interface. Advances in coating technology have helped suppress these detrimental reactions to a certain extent [3]. We demonstrate the use of differential electrochemical mass spectrometry (DEMS) on evaluating the stability of a protective surface coating [4]. Analysis of the gas evolved provides insights into possible reaction mechanisms at the CAM/SE interface. DEMS was also used to investigate the practical safety performance of sulfide-based SSBs with respect to possible harmful gas evolution such as H 2 S and SO 2 [5]. Key Words: All-solid-state battery, differential electrochemical mass spectrometry, electrochemical energy storage References Janek, W. Zeier, Nat. Energy, 1 (2016) 16141. J. Nam, D. Y. Oh, S. H. Jung, Y. S. Jung, J. Power Sources, 375 (2018) 93–101. -Y. Kim, F. Strauss, T. Bartsch, J. H. Teo, T. Hatsukade, A. Mazilkin, J. Janek, P. Hartmann, T. Brezesinski, Chem. Mater., 31 (2019) 9664 – 9672. Bartsch, F. Strauss, T. Hatsukade, A. Schiele, A-Y. Kim, P. Hartmann, J. Janek, T. Brezesinski, ACS Energy Lett., 3 (2018) 2539–2543. Strauss, J. H. Teo, A. Schiele, T. Bartsch, T. Hatsukade, P. Hartmann, J. Janek, T. Brezesinski, ACS Appl. Mater. Interfaces, 12 (2020), 20462–20468.
Silicon nitride CMOS-compatible platform for integrated photonics applications at visible wavelengths (2013)

Silicon nitride is demonstrated as a high performance and cost-effective solution for dense integrated photonic circuits in the visible spectrum. Experimental results for nanophotonic waveguides fabricated in a standard CMOS pilot line with losses below 0.71dB/cm in an aqueous environment and 0.51dB/cm with silicon dioxide cladding are reported. Design and characterization of waveguide bends, grating couplers and multimode interference couplers (MMI) at a wavelength of 660 nm are presented. The index contrast of this technology enables high integration densities with insertion losses below 0.05 dB per 90° bend for radii as small as 35 µm. By a proper design of the buried oxide layer thickness, grating couplers with efficiencies above 38% for the TE polarization have been obtained.
Identification of signature volatiles to discriminate Candida albicans, glabrata, krusei and tropicalis using gas chromatography and mass spectrometry (2015)

Oral candidiasis is the most frequent fungal infection of the oral cavity. Clinical diagnoses require mycological confirmation, which is time-consuming in case of culture testing. The aim of the study was to identify signature volatiles to develop a chairside breath test to diagnose oral candidiasis. Headspaces above Candida albicans, glabrata, tropicalis, krusei cultures, and growth media as control were analysed after eight and 24 h using offline gas chromatography and mass spectrometry. The identification of signature volatiles was assisted using various microbial databases. Retrieved volatile patterns enabled Candida species discrimination in vitro. For C. albicans 3-methyl-2-butanone and styrene and for C. krusei a combination of p-xylene, 2-octanone, 2-heptanone and n-butyl acetate were found to be specific. 1-hexanol was found in C. tropicalis, but is emitted by a variety of other microorganisms. C. glabrata was characterised through the absence of these volatiles. The development of a breath test is a promising approach in confirming suspicions of oral candidiasis. To confirm the retrieved results in vivo, breath tests in affected and healthy subjects have to be performed.
Two-step breakdown of a SiN membrane for nanopore fabrication: Formation of thin portion and penetration (2018)

For the nanopore sensing of various large molecules, such as probe-labelled DNA and antigen-antibody complexes, the nanopore size has to be customized for each target molecule. The recently developed nanopore fabrication method utilizing dielectric breakdown of a membrane is simple and quite inexpensive, but it is somewhat unsuitable for the stable fabrication of a single large nanopore due to the risk of generating multiple nanopores. To overcome this bottleneck, we propose a new technique called “two-step breakdown” (TSB). In the first step of TSB, a local conductive thin portion (not a nanopore) is formed in the membrane by dielectric breakdown. In the second step, the created thin portion is penetrated by voltage pulses whose polarity is opposite to the polarity of the voltage used in the first step. By applying TSB to a 20-nm-thick SiN membrane, a single nanopore with a diameter of 21–26 nm could be fabricated with a high yield of 83%.
Bioelectronic Approaches to Control Neuroimmune Interactions in Acute Kidney Injury (2018)

Recent studies have shown renal protective effects of bioelectric approaches, including ultrasound treatment, electrical vagus nerve stimulation, and optogenetic brainstem C1 neuron stimulation. The renal protection acquired by all three modalities was lost in splenectomized mice and/or α7 subunit of the nicotinic acetylcholine receptor-deficient mice. C1 neuron-mediated renal protection was blocked by β2-adrenergic receptor antagonist. These findings indicate that all three methods commonly, at least partially, activate the cholinergic anti-inflammatory pathway, a well-studied neuroimmune pathway. In this article, we summarize the current understanding of neuroimmune axis-mediated kidney protection in preclinical models of acute kidney injury by these three modalities. Examination of the differences among these three modalities might lead to a further elucidation of the neuroimmune axis involved in renal protection and is of interest for developing new therapeutic approaches.
Controlled assembly of artificial 2D materials based on the transfer of oxo-functionalized graphene (2019)

Functionalized 2D materials have unique properties, but are currently not used for the assembly of van der Waals heterostructures. Here, we present the controlled transfer of artificially synthesized, polar and highly transparent oxo-functionalized graphene, which can decouple graphene layers.
Idiomarina planktonica sp. nov., isolated from a saline lake (2014)

A Gram-stain-negative bacterium, strain TS-T11(T), was isolated from Tuosu lake, a saline lake (salinity 5.4%, w/v) in the Qaidam basin, Qinghai province, China. Its taxonomic position was determined by using a polyphasic approach. Cells of strain TS-T11(T) were non-spore-forming rods, 0.6-0.8 µm wide and 0.8-2.2 µm long, and motile by means of a single polar flagellum. Strain TS-T11(T) was strictly heterotrophic and aerobic. Cells were positive for catalase and oxidase. Growth was observed in the presence of 0.5-11.0% (w/v) NaCl (optimum 4.0-6.0%), at 4-40 °C (optimum 30-35 °C) and at pH 6.0-10.5 (optimum pH 7.5-8.5). Strain TS-T11(T) contained iso-C15:0, iso-C17:0 and iso-C17:1ω9c as the predominant fatty acids (>10%). The major respiratory quinone was Q-8. The polar lipids consisted of a mixture of phosphatidylethanolamine, phosphatidylglycerol, diphosphatidylglycerol and nine uncharacterized phospholipids. The G+C content of genomic DNA was 46.8 mol% (Tm). Phylogenetic trees based on 16S rRNA gene sequences showed that strain TS-T11(T) was associated with the genus Idiomarina, and showed highest 16S rRNA gene sequence similarity to Idiomarina aestuarii KYW314(T) (97.4%) and Idiomarina salinarum ISL-52(T) (97.4%). DNA-DNA relatedness of strain TS-T11(T) to I. aestuarii JCM 16344(T) and I. salinarum DSM 21900(T) was 22.2 ± 2.4 and 11.5 ± 1.6%, respectively. Based on the data presented above, it was concluded that strain TS-T11(T) represents a novel species of the genus Idiomarina, for which the name Idiomarina planktonica sp. nov. is proposed. The type strain is TS-T11(T) ( = CGMCC 1.12458(T) = JCM 19263(T)).
<title>Extraction of text boxes from engineering drawings</title> (1992)

Textboxes are minimum size rectangles enclosing blocks of text in engineering drawings. Their separation from the graphics surrounding them is a first step in character recognition, and is a part of the Machine Drawing Understanding System, currently under development. Textbox extraction is preceded by orthogonal zig-zag vectorization, arc segmentation, and arrowhead recognition. It is done by clustering the remaining short bars that are located close to each other through a region growing process. Further refinements follow which improve the ability of the process to outline the real textboxes.