gebhart/patrepeval huggingface dataset:
A Compact MIMO UWB Antenna Using Different Types of Dipoles with Low Mutual Coupling (2016)

In this paper, a new MIMO antenna for ultra-wide band (UWB) applications is designed and proposed. The proposed MIMO antenna consists of two single UWB antenna elements, one acts as a magnetic dipole while the other as an electric one, to reduce mutual coupling. In order to reduce further the mutual coupling, a copper stub is used to isolate the two antenna elements. The designed MIMO UWB antenna provides a broad operating bandwidth from 3.1GHz to 10.6GHz, while achieving low mutual coupling and VSWR ≤ 2. Various performance characteristics of the antenna such as radiation patterns, VSWR, and the maximal gain are thoroughly investigated by simulations and experiments.
Non imidazole H3-receptor histamine antagonists (1999)

Histamine is a biogenic amine inducing a range of physiological responses through three receptor subtypes. The role of the presynaptic H3 receptor in the central nervous system is regulatory by way of a negative feedback mechanism. A brain-penetrating H3-receptor antagonist would increase neurotransmission and is likely to have therapeutic applications in the treatment of disorders such as memory and learning deficits, sleep disturbance, epilepsy and Alzheimer's disease. So far, a common feature among H3-receptor ligands is an imidazole ring which is very polar and gives poor lipophilicity. This can be detrimental to brain penetration, hence it is important to design non imidazole antagonists that are less polar in order to increase brain penetration. However, it is thought that the imidazole ring is essential for activity at H3 receptors. By adding an alkyl spacer and a lipophilic group which is thought to reach an additional binding site, we were able to remove the imidazole ring without losing the activity. The aryloxyalkylamines prepared by various known synthetic methods were submitted as salts of an organic or inorganic acid to facilitate their solubility in water. Their biological activity was determined in rodents on brain preparations (in vitro) or given orally to live animals (in vivo). Modifications of the structure of the lead compound and structure-activity studies led to the synthesis of a series of orally active substituted phenoxypropylpiperidines some of which are the most potent non imidazole H3 receptor antagonists described so far. Over 100 novel compounds were prepared and tested for this project. The most active of them is at least twice as potent in vitro and 8 times as active in vivo as the reference H3-receptor antagonist thioperamide. In addition, another series of aryloxyalkylamines as antagonists at the NMDA receptor is investigated.
Locked nucleic acid molecular beacons for intracellular mRNA monitoring (2006)

We have designed, synthesized, and investigated a novel molecular beacon (MB) using locked nucleic acid (LNA) bases for intracellular mRNA monitoring. This new LNA-MB has several useful properties including: very high melting temperature; excellent affinity for complementary sequences; superior single base mismatch discrimination capability; stablity against nuclease digestion; and not binding with single-stranded DNA binding proteins. All of these properties are highly advantageous for a molecular tool for various intracellular studies of biochemical, biological and medical significance.
CONVECTION HEAT TRANSFER (1999)

Fundamental Principles Laminar Boundary Layer Flow Laminar Duct Flow External Natural Convection Internal Natural Convection Transition to Turbulence Turbulent Boundary Layer Flow Turbulent Duct Flow Free Turbulent Flows Convection with Change of Phase Mass Transfer Convection in Porous Media.
Induction of release of secretory nonpancreatic phospholipase A2 from human articular chondrocytes. (1995)

Human articular chondrocytes synthesize and constitutively release sPLA2. Such continuous release is most probably responsible for the high concentration of sPLA2 in articular cartilage and may be the source of synovial fluid sPLA2. To our knowledge, human articular chondrocytes are the only sPLA2 producing cells tested to date that do not respond to cytokine stimulation with increased sPLA2 activity; yet enhancement was seen with 8-bromo cAMP. It seems therefore that, human articular chondrocytes possess signalling mechanisms for the release of sPLA2 unlike those from other mammalian cells. The significance of this observation remains to be elucidated.
Properties of CuPc/Se organics-inorganic hybrid thin films growth by electron beam evaporation technique (2007)

Organic and Inorganic materials with copper (II) phthalocyanine (CuPc) and selenium (Se) were deposited to implement hybrid thin films by multi pocket electron beam evaporation technique. Crystallization of hybrid films was performed by x-ray diffraction (XRD) spectroscopy. XRD pattern exhibits monoclinic α-phase crystallizations structure of CuPc. Influences of the CuPc thickness on the crystalline structure of selenium films were obtained. As the thickness of CuPc layer was increased to 100 nm, the hexagonal Se was observed. Optical absorption spectra were measured by UV-Visible spectrophotometer. Results of hybrid absorption spectra were revealed to absorption spectra of CuPc and Se. Surface roughness of films can confirm with XRD spectra. The surface morphology was characterized by atomic force microscope (AFM) with non-contact mode, it illustrate the point that hybrid thin films is nanocrystal structure.
Mat & Met S5 from An Antibody–Drug Conjugate Targeting MUC1-Associated Carbohydrate CA6 Shows Promising Antitumor Activities (2023)

&lt;p&gt;Glycotope analysis of CA6 antigen&lt;/p&gt;
Machine Learning OCT Predictors of Progression from Intermediate Age-Related Macular Degeneration to Geographic Atrophy and Vision Loss (2022)

We propose a risk-stratified classification of iAMD based on the combination of OCT-derived retinal features, age, gender and systemic variables for progression to OCT-determined GA and/or VA loss. After external validation, the composite early endpoints may be used as exclusion or inclusion criteria for future clinical studies of iAMD focused on prevention of GA progression or VA loss.
Sustained Low Serum Substance P Levels in Non-Surviving Septic Patients (2017)

Previously, researchers found higher serum substance P (SP) concentrations in survivors of severe sepsis than in non-survivors at the time of severe sepsis diagnosis. The objectives of our current study were to determine whether there is an association between serum SP levels during the first week and sepsis mortality, sepsis severity, serum levels of tumor necrosis factor (TNF)-α and interleukin (IL)-10, and whether serum SP levels during the first week could be used as a biomarker of sepsis mortality. We determined serum concentration of SP, TNF-α, and IL-10 at days 1, 4, and 8. The end-point of the study was mortality at 30 days. We found that <b>n</b>on-survivor (<i>n</i> = 104) compared to survivor patients (<i>n</i> = 206) showed lower serum SP levels at days 1, 4, and 8 (<i>p <</i> 0.001). Multiple logistic regression analyses showed an association between 30-day mortality and serum SP levels at days 1, 4, and 8 (<i>p</i> < 0.001) controlling for SOFA score, diabetes mellitus, age, and lactic acid levels. The most interesting findings of our study were that there is an association between serum SP levels during the first week and sepsis mortality, and that serum SP levels during the first week could be used as a biomarker of sepsis mortality.
Challenging Recently Published Parameter Sets for Entropy Measures in Risk Prediction for End-Stage Renal Disease Patients (2017)

Heart rate variability (HRV) analysis is a non-invasive tool for assessing cardiac health. Entropy measures quantify the chaotic properties of HRV, but they are sensitive to the choice of their required parameters. Previous studies therefore have performed parameter optimization, targeting solely their particular patient cohort. In contrast, this work aimed to challenge entropy measures with recently published parameter sets, without time-consuming optimization, for risk prediction in end-stage renal disease patients. Approximate entropy, sample entropy, fuzzy entropy, fuzzy measure entropy, and corrected approximate entropy were examined. In total, 265 hemodialysis patients from the ISAR (rISk strAtification in end-stage Renal disease) study were analyzed. Throughout a median follow-up time of 43 months, 70 patients died. Fuzzy entropy and corrected approximate entropy (CApEn) provided significant hazard ratios, which remained significant after adjustment for clinical risk factors from literature if an entropy maximizing threshold parameter was chosen. Revealing results were seen in the subgroup of patients with heart disease (HD) when setting the radius to a multiple of the data’s standard deviation ( r = 0.2 · σ ); all entropies, except CApEn, predicted mortality significantly and remained significant after adjustment. Therefore, these two parameter settings seem to reflect different cardiac properties. This work shows the potential of entropy measures for cardiovascular risk stratification in cohorts the parameters were not optimized for, and it provides additional insights into the parameter choice.
Perceptions and experiences of financial incentives: a qualitative study of dialysis care in England (2014)

The impact of financial incentives designed at a policy level is influenced by the understanding of cost and benefits at the local operational level. In a situation where costs are unclear, incentives which are based on the improvement of profit margins have a smaller impact than incentives which provide an additional direct payment, even if this extra financial support is relatively small.
PROSTAGLANDIN PRODUCTION BY RABBIT ISOLATED JEJUNUM AND ITS RELATIONSHIP TO THE INHERENT TONE OF THE PREPARATION (1976)

1 Pieces of rabbit jejunum were bathed in Krebs solution at 37 degrees C in an isolated organ bath bubbled with O2 and 5% CO2. The bathing fluid was collected regularly and assayed for prostaglandins. 2 The preparations maintained a continuous sub-maximal muscle contraction, referred to as inherent 'tone'. Prostaglandins E2 and F2alpha were continuously generated by the intestine and released into the bathing fluid. The amounts released first declined over 2 h and then steadily increased. The release was also greater after 48 h storage in the refrigerator and after mechanical damage. 3 There was no change in prostaglandin release when the rabbit jejunum was contractd by acetylcholine or physostigmine or relaxed by adrenaline, hyoscine, papaverine, dinitrophenol, or calcium-free Krebs solution. 4 Addition to the bathing fluid of the prostaglandin precursor, arachidonic acid, did not increase the release of prostaglandins although it contracted the tissue. Thus, output of prostaglandins from the tissue was not limited by substrate concentration but more probably by the capacity of the prostaglandin synthetase. 5 Prostaglandin output was decreased by bubbling the bathing fluid with N2 rather than O2; at the same time the preparation relaxed. 6 Aspirin-like drugs such as indomethacin also decreased or abolished prostaglandin formation and this, too, was accompanied by loss of tone of the isolated preparation. 7 Pieces of rabbit jejunum stored in Krebs solution containing indomethacin initially released little or no prostaglandin into the bathing fluid. However, prostaglandin release increased with repeated washing of the preparation. 8 The results suggest that intra-mural prostaglandin production contributes to the inherent tone of the rabbit jejunum, that trauma increases prostaglandin production and that the inhibitory effects of anoxia are linked with the lack of prostaglandin production and activity. The relevance of these findings to intestinal activity in vivo is discussed.
Biomedical applications of polyelectrolyte coated spherical gold nanoparticles (2019)

Surface modified gold nanoparticles are becoming more and more popular for use in biomaterials due to the possibility for specific targeting and increased biocompatibility. This review provides a summary of the recent literature surrounding polyelectrolyte coatings on spherical gold nanoparticles and their potential biomedical applications. The synthesis and layer-by layer coating approach are briefly discussed together with common characterisation methods. The potential applications and recent developments in drug delivery, gene therapy, photothermal therapy and imaging are summarized as well as the effects on cellular uptake and toxicity. Finally, the future outlook for polyelectrolyte coated gold nanoparticles is explored, focusing on their use in biomedicine.
Structural control of the triplet-singlet equilibrium in cyclophane diarylcarbenes (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructural control of the triplet-singlet equilibrium in cyclophane diarylcarbenesR. Alt, I. R. Gould, H. A. Staab, and N. J. TurroCite this: J. Am. Chem. Soc. 1986, 108, 22, 6911–6914Publication Date (Print):October 1, 1986Publication History Published online1 May 2002Published inissue 1 October 1986https://pubs.acs.org/doi/10.1021/ja00282a013https://doi.org/10.1021/ja00282a013research-articleACS PublicationsRequest reuse permissionsArticle Views133Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Sorbent selection for the CAFB residual oil gasification demonstration plant. Final task report Apr 1975--Mar 1976 (1977)

The report gives results of evaluations of limestones from Texas and Mexico as candidate sulfur sorbents for the chemically active fluid-bed (CAFB) gasification demonstration plant at San Benito, Texas. Preliminary laboratory tests show that three limestones quarried in Texas and one quarried in Mexico should be suitable sorbents, based on availability, chemical characterization, physical characterization, attrition behavior, and chemical reactivity as sulfur sorbents. Current sorbent selection criteria are being refined.
Novel simple method for determination of refractive index of optical monomode slab waveguides (1985)

A novel simple nondestructive interference method is proposed for measuring the refractive index of optical monomode slab waveguides and cladding layers of sufficient thickness. This method has been used to investigate thin films of III-V compounds on binary substrates, especially GaInAsP/InP, with respect to application for integrated optical devices in the transparent wavelength region. The experimental results are compared with theoretical calculations.
DERECHOS HUMANOS: UNA IDEA INCOMPLETA (2004)

En la Ilustración, culminan tres importantes esfuerzos sobre los derechos humanos: el de secularizar los antiguos derechos naturales, el de elaborar una lista de derechos y el de convertirlos en instrumento de reivindicación política. Desde entonces, no ha habido ningún desarrollo teórico adicional de la idea. En nuestros días, el concepto de derechos humanos está mucho más indeterminado que en el siglo XVIII porque nos falta el consenso en los ejemplos que lo concretan. La tarea de nuestro tiempo respecto a los derechos humanos puede muy bien ser la de corregir esa indeterminación, completando así la labor de la Ilustración.
ERBB1 and ERBB2 Have Distinct Functions in Tumor Cell Invasion and Intravasation (2009)

ERBB1 and ERBB2 inhibition can rapidly block tumor cell invasive properties. In addition, we differentiate for the first time the contributions of ERBB1 and ERBB2 to the key metastatic properties of in vivo tumor cell invasion and intravasation. These experiments temporally and molecularly separate two key stages in tumor cell entry into blood vessels: invasion and intravasation. These results indicate that ERBB inhibition should be considered for blocking other tumor cell malignant properties besides growth.
Strength of Sieved Only Oil Palm Ash Foamed Concrete (2015)

Oil palm ash (OPA) is a waste material produced by countries having a blooming palm oil industry.Increasing palm oil production, the quantities of OPA continue to increase.However, its utilisation remains minimal and most of it is disposed of in landfills, causing environmental hazards.This study investigated the strength of foamed concrete incorporating sieved only OPA as a partial cement replacement.A foamed concrete mix of 1 part binder and 2 parts filler with a plastic density of 1450 kg/m 3 has been used.Cement is replaced by OPA at replacement levels of 25 to 65% by weight of binder.Compressive, tensile splitting and flexural strengths have been investigated at the ages of 7, 14, 28 and 56 days.A foamed concrete mix with a 25% OPA content showed superior strengths than those exhibited by the control mix, hence, producing a greener and cheaper foamed concrete.
Différences entre la morphologie testiculaire de <em>Fasciola hepatica</em> et <em>Fasciola gigantica</em> (1970)

cf. fichier PDF de l'article.
NOD.c3c4 congenic mice develop autoimmune biliary disease that serologically and pathogenetically models human primary biliary cirrhosis (2006)

Primary biliary cirrhosis (PBC) is an autoimmune disease with a strong genetic component characterized by biliary ductular inflammation with eventual liver cirrhosis. The serologic hallmark of PBC is antimitochondrial antibodies that react with the pyruvate dehydrogenase complex, targeting the inner lipoyl domain of the E2 subunit (anti-PDC-E2). Herein we demonstrate that NOD.c3c4 mice congenically derived from the nonobese diabetic strain develop an autoimmune biliary disease (ABD) that models human PBC. NOD.c3c4 (at 9-10 wk, before significant biliary pathology) develop antibodies to PDC-E2 that are specific for the inner lipoyl domain. Affected areas of biliary epithelium are infiltrated with CD3+, CD4+, and CD8+ T cells, and treatment of NOD.c3c4 mice with monoclonal antibody to CD3 protects from ABD. Furthermore, NOD.c3c4-scid mice develop disease after adoptive transfer of splenocytes or CD4+ T cells, demonstrating a central role for T cells in pathogenesis. Histological analysis reveals destructive cholangitis, granuloma formation, and eosinophilic infiltration as seen in PBC, although, unlike PBC, the extrahepatic biliary ducts are also affected. Using a congenic mapping approach, we define the first ABD (Abd) locus, Abd1. These results identify the NOD.c3c4 mouse as the first spontaneous mouse model of PBC.
Semantic-based generation of generic-API adapters for portable cloud applications (2016)

The lack of standard or common API among heterogeneous PaaS platforms makes cloud developers locked inside a specific PaaS platform and not able to easily migrate their applications or data. One approach for application portability is to implement applications using a generic API and develop an adapter for each specific PaaS platform. Whereas the generic API provides cloud developers with a set of generic methods, each adapter translates these generic methods into their corresponding specific-API calls. However, updates to a specific API (e.g., renaming methods or changing input parameters) may require re-factoring or even re-implementation of its corresponding adapter; otherwise code that uses the adapter will not run correctly with the new API. We use the term API synchronization to name this problem. The work in this paper addresses the API synchronization problem, whereby a method for automatic adapter generation that is based on semantic annotations and semantic search is presented. The proposed method requires that the specific-API methods are annotated to describe the conceptual meanings of method inputs and outputs based on a common domain ontology. The proposed method was evaluated using a case study for a generic API of the blob storage service. The automatically generated adapters of the blob storage service were used to implement a generic application and to deploy it on two different PaaS platforms, namely Google App Engine and Windows Azure.
TPPP acts downstream of RhoA-ROCK-LIMK2 to regulate astral microtubule organization and spindle orientation (2012)

The actin cytoskeleton in eukaryotic cells undergoes drastic rearrangement during mitosis. The changes to the actin cytoskeleton are most obvious in the adherent cells, where the actin stress fibres are disassembled, and the cortical actin network becomes more prominent with concomitant increase in cell rigidity as cells round up and enter mitosis. Although the regulatory connections between the actin cytoskeleton and the early mitotic events are apparent, the mechanisms that govern these links are not well understood. Here, we report that LIMK1 and LIMK2, the downstream effectors of RhoA and ROCK, regulate centrosome integrity and astral microtubule organization, respectively. Surprisingly, LIMK1 and cofilin are not involved downstream of RhoA and ROCK in the regulation of astral microtubule organization. Instead, we find that LIMK2 acts through TPPP in the regulation of astral microtubule organization, whereas both LIMK1 and LIMK2 affect centrosome focusing. Both phenotypes are tightly coupled to spindle orientation in the mitotic cells. Thus, our results reveal a new regulatory link between the actin cytoskeleton and the mitotic spindle during the early stages of mitosis.
Inactivation of Rubella Virus by Gamma Radiation (1969)

The Gilchrist and M-33 strains of rubella virus exposed in the frozen state to (137)Ce or (60)Co were inactivated exponentially according to "one hit" kinetics. There was no difference in the radiosensitivity of the two strains. Experimental D(37) values for both strains ranged from 1.9 x 10(5) to 2.9 x 10(5) rads, and computed radiosensitive molecular weights ranged from 2.6 x 10(6) to 4.0 x 10(6) daltons.
A multimedia system for authoring motion pictures (1996)

MAD (Movie Authoring and Design) is a novel design and authoring system that facilitates the process of creating dynamic visual presentations such as motion pictures and lecture-demonstrations.
CTH07-1: Effect of Feedback Delay on Multi-Antenna Limited Feedback for Temporally-Correlated Channels (2006)

A novel method based on Markov chain theory is proposed for analyzing the effect of feedback delay on a transmit beamforming system with limited feedback. Using this method, the ergodic capacity with delayed feedback of channel state information is derived. The capacity gain with respect to the case of no feedback is shown to decrease at least exponentially with the feedback delay. From these results, useful design guidelines can be derived for choosing system parameters including the vehicular speed and the tolerable feedback delay.
A comprehensive training program for multidisciplinary treatment plans. (1989)

A client-oriented treatment plan that will direct and coordinate health care staff, thereby ensuring efficient quality client care, is a worthy goal. After planning, implementing, and evaluating a training program for this purpose, the authors concluded that the key to quality client care and successful implementation of this program lies in proper preparation and administrative support.