gebhart/patrepeval huggingface dataset:
Is It Possible to Treat Equine Papillomatosis with Ivermectin Given Orally (2010)

Summary This case report aims to evaluate the effect of ivermectin in the treatment of a horse with papillomatosis. The horse was a 14-month-old mare, with cutaneous papillomatosis diagnosed by clinical and histopahological examinations. The history revealed that papillomas had developed and progressed in the last 2 months. A single shot of ivermectin (Eqvalan paste®, Topkim, Turkey) at a dose of 200 mcg/kg was orally administered to the horse. The horse was observed at 7 th , 15 th and 30 th days and no other treatment during the recovery period. Papillomas regressed clearly on the 7 th day after the administration of ivermectin treatment and regressed nearly 90% on the 15 th day and, showed complete remission on the 30 th day. The results obtained in this case indicated that ivermectin might be effect in the treatment of equine papillomatosis.
DKAL: Distributed-Knowledge Authorization Language (2008)

DKAL is a new declarative authorization language for distributed systems. It is based on existential fixed-point logic and is considerably more expressive than existing authorization languages in the literature. Yet its query algorithm is within the same bounds of computational complexity as e.g. that of SecPAL. DKAL's communication is targeted which is beneficial for security and for liability protection. DKAL enables flexible use of functions; in particular principals can quote (to other principals) whatever has been said to them. DKAL strengthens the trust delegation mechanism of SecPAL. A novel information order contributes to succinctness. DKAL introduces a semantic safety condition that guarantees the termination of the query algorithm.
Encapsulation of Hemin in Metal–Organic Frameworks for Catalyzing the Chemiluminescence Reaction of the H2O2–Luminol System and Detecting Glucose in the Neutral Condition (2015)

Novel metal-organic frameworks (MOFs) based solid catalysts have been synthesized by encapsulating Hemin into the HKUST-1 MOF materials. These have been first applied in the chemiluminescence field with outstanding performance. The functionalized MOFs not only maintain an excellent catalytic activity inheriting from Hemin but also can be cyclically utilized as solid mimic peroxidases in the neutral condition. The synthesized Hemin@HKUST-1 composites have been used to develop practical sensors for H2O2 and glucose with wide response ranges and low detection limits. It was envisioned that catalyst-functionalized MOFs for chemiluminescence sensing would have promising applications in green, selective, and sensitive detection of target analytes in the future.
Research trends of connected education from kindergarten to elementary school -Based on domestic journals written from 2000 to 2017 - (2018)

본 연구는 유&#8228;초 연계에 대한 최근 경향을 분석하는 것을 목적으로 2000년부터 2017년까지의 국내 석 박사 학위논문 및 학술지에 발표된 총205편의 논문을 분석하였다. 첫째, 연도별 연구동향은 2000년 중반에 증가하기 시작하여 현재까지 지속적으로 연구가 진행되고 있다. 둘째, 연구내용의 동향은 교육과정 및 프로그램 관련 연구가 가장 많았고, 그 다음으로는 인식 및 요구도에 대한 내용이 많이 나타났다. 셋째, 연구유형 동향은 문헌연구가 가장 많았고, 그 다음으로는 조사연구, 실험연구 순으로 나타났다. 넷째, 연구대상 동향은 연구물&#8228;문헌이 가장 많았고, 교사, 아동, 학부모순으로 나타났다. 다섯째, 자료수집방법 동향은 문헌분석법이 가장 높게 나타났고, 그 다음으로는 설문지법으로 나타났다. 이러한 연구결과를 바탕으로 유아교육기관과 초등학교의 연계를 경험하는 아동을 대상으로 관찰 및 면접을 통한 깊이 있는 질적연구와 종단연구, 특별한 요구를 가진 아동들 의 연계 문제 등에 관한 후속연구가 이루어질 것을 제언하였다.The purpose of this study is to analyze research trends on connected education from kindergarten to elementary school, for this, total 205 investigating journal articles and dissertations published from 2000 up to 2017 were investigated. The areas of analyzing criteria were research style, subjects, number of the study, research methods, and the content of the study. The results of this study offer meaningful information to develop connected education from kindergarten to elementary school. Based on study results, it is suggested to conduct follow-up studies, with qualitative and longitudinal study, through the various approaches and data collection by observation and interviews children experiencing in connected education from kindergarten to elementary school.
Reconfiguration of Industrial Embedded Control Systems (2010)

This research work deals with the development of safety reconfigurable embedded control systems following the international industrial component-based standard IEC61499. According to this standard, a function block (FB) is a functional unit of software and a control application a FB network that has to meet functional and temporal properties described in user requirements. We define in the book chapter a new semantic of the reconfiguration where a crucial criterion to consider is the automatic improvement of the system performance at run-time. If a reconfiguration scenario is applied at run-time, then the FB network implementing the system is totally changed or modified. To handle all possible reconfiguration forms, we propose thereafter an agent-based architecture that applies automatic reconfigurations to adapt the system according to well defined conditions and we model this agent with nested state machines according to the formalism of net condition/event systems which is an extension of the Petri net formalism. In order to satisfy user requirements, we specify the functional and temporal properties with the temporal logic CTL (as well as its extensions ECTL and TCTL) and we apply the model checker SESA to check the whole system behavior. To assign this reconfigurable system into the execution environment, we define thereafter an approach based on the exploration of reachability graphs to construct feasible OS tasks that encode the FB network corresponding to each reconfiguration scenario. Therefore, the system is implemented with sets of OS tasks where each set is to load in memory when the corresponding scenario is applied by the Agent. We developed the tool X-Reconfig to support these contributions that we apply on the FESTO and EnAS benchmark production systems available in our research laboratory.
Enhanced Contrast Ratios and Rapid Switching in Electrochromics Based on Poly(3,4-propylenedioxythiophene) Derivatives (1999)

Dark opaque blue to transmissive light blue is the color transition that poly(3,4-propylenedioxythiophene) (PProDOT) and derivatives undergo when switched from their reduced to oxidized state. These polymers are very promising electrochromic materials—they exhibit more rapid switching, lower oxidation potentials, and greater stability than polythiophene. The synthesis and optical properties of the disubstituted derivative PProDOT–Me2 are reported and compared with those of PProDOT–Me and PProDOT. Substitution is found to improve the polymer's electrochromic properties.
Dichopetala Locality Database (2014)

Myotonic dystrophy is a relatively common disorder. Since the clinical expression is highly variable, diagnosis is often made only after the birth of an infant with severe congenital myotonic dystrophy. Seven such cases are described. A history of obstetric complications was present in the six multiparous mothers. Neither the neonatal features nor the pregnancy complications are specific, but their combinations should suggest the diagnosis, which can be confirmed by neurologic evaluation of the infant's mother.
Decrease in Postprandial Insulin and Glucose Concentrations by Guar and Pectin (1977)

Postprandila glycaemia and rise in serum insulin after carbohydrate-containing meals were reduced by the addition of guar flour or pectin, or both. After a liquid test meal (four subjects) the 30-min blood glucose was reduced from 6.33 +/- 0.19 mmol/litre (114 +/- mg/dl), mean +/- SEM, in the control subjects of 4.77 +/- 0.17 mmol/litre (86 +/- 3 mg/dl) by addition of guar gum (P less than 0.05). The mean insulin level was also significantly lower at 15 min. A breakfast test meal (bread, butter, marmalade, and tea) resulted in a mean 15-min blood glucose of 6.18 +/- 0.21 mmol/litre (111 +/- 4 mg/dl) in eight subjects; 10 g of pectin added to the marmalade reduced this level to 5.64 +/- 0.17 mmol/litre (102 +/- 3 mg/dl) (P less than 0.01). The insulin levels were significantly lower at 15, 30, and 45 min. A similar meal in which guar was added to the bread and pectin to the marmalade resulted in significant reductions of blood glucose at 15 min (P less than 0.002) and 30 min (P less than 0.01). The insulin values were also significantly lower throughout the first 90 min of the test. This action of unavailable carbohydrate may prove useful in the dietary control of diabetes.
Fabrication of 10-nm-Order Block Copolymer Self-Assembled Nanodots for High-Density Magnetic Recording (2011)

In this work, we investigated the fabrication of 10-nm-order block copolymer self-assembled nanodots using high-etching-selectivity polystyrene–poly(dimethylsiloxane) (PS–PDMS) block copolymers for high-density storage devices. We adopted PS–PDMS polymers with two different molecular weights of 13,500–4,000 and 11,700–2,900. With decreasing molecular weight, the nanodot size decreased from 12 to 10 nm, and the pitch correspondingly decreased from 22 to 20 nm. The PS–PDMS film thickness is the critical-factor to determine whether nanodot arrays can form on a large area or not. It was demonstrated that the thicknesses of 36 and 33 nm were optimal for the PS–PDMS polymers of 13,500–4,000 and 11,700–2,900, respectively. The limitation in the selection of PS–PDMS to form a smaller size of self-assembled nanodots is also predicted. This work promises to open way toward 1.6 Tbit/in. 2 storage device with cheap cost production.
Controlling the Molecular Direction of Dinuclear Ruthenium Complexes on HOPG Surface through Noncovalent Bonding (2017)

We synthesized three types of binuclear Ru complexes (1-3) that contain pyrene anchors for the adsorption of 1-3 onto nanocarbon materials via noncovalent π-π interactions, in order to investigate their adsorption onto and their desorption from highly ordered pyrolytic graphite (HOPG). The adsorption saturation for 1 (6.22 pmol/cm<sup>2</sup>), 2 (2.83 pmol/cm<sup>2</sup>), and 3 (3.53 pmol/cm<sup>2</sup>) on HOPG was obtained from Langmuir isotherms. The desorption rate from HOPG electrodes decreased in the order 3 (2.4 × 10<sup>-5</sup> s<sup>-1</sup>) > 2 (1.4 × 10<sup>-5</sup> s<sup>-1</sup>) ≫ 1 (1.8 × 10<sup>-6</sup> s<sup>-1</sup>). These results indicate that the number of pyrene anchors and their position of substitution in such complexes strongly affect the desorption behavior. However, neither the free energy of adsorption (ΔG<sub>ads</sub>) nor the heterogeneous electron-transfer rate (k<sub>ET</sub>) showed any significant differences among 1-3, albeit that the surface morphologies of the modified HOPG substrates showed domain structures that were characteristic for each Ru complex. In the case of 3, the average height changed from ∼2 to ∼4 nm upon increasing the concentration of the solution of 3 that was used for the surface modification. In contrast, the height for 1 and 2 remained constant (1.5-2 nm) upon increasing the concentration of the complexes in the corresponding solutions. While the molecular orientation of the Ru-Ru axis of 3 relative to the HOPG surface normal changed from parallel to perpendicular, the Ru-Ru axis in 1 and 2 remained parallel, which leads to an increased stability of 1 and 2.
Mini-UAV-Borne LIDAR for Fine-Scale Mapping (2010)

Light detection and ranging (LIDAR) systems based on unmanned aerial vehicles (UAVs) recently are in rapid advancement, while mini-UAV-borne laser scanning has few reported progress, notwithstanding so extensively required. This study established a pioneered mini-UAV-borne LIDAR system - Sensei, schematically with an Ibeo Lux scanner mounted on a small Align T-Rex 600E helicopter. Furthermore, the associated data processing involved in the coordinate triple, pulse intensity, and multiechoes per pulse was explored to validate its applicability for fine-scale mapping, in terms of, e.g., tree height estimation, pole detection, road extraction, and digital terrain model refinement. The feasibility and advantages of mini-UAV-borne LIDAR have been demonstrated by the promising results based on the real-measured data.
A novel stereo object segmentation algorithm using disparity and temporal information (2013)

A novel stereoscopic object segmentation method based on disparity and temporal-spatial cues is proposed in this paper. First, a foreground layer map is generated from a patched disparity image and a motion object map is produced using an adaptive reference frame selection method. Then the intersection of these two maps is used to extract the foreground motion objects. In the foreground layer map generation stage, two intensity image sequences of the input stereo videos are separately mapped to the rank space by a rank transform to eliminate the parameter deviation of binocular cameras, and reduce the interference of the environment fluctuation and noises. A fast multi-window matching strategy is proposed to speed up the stereo matching process. Then, a disparity patching process is performed to bridge the disparity discontinuity in the smooth region to improve the accuracy of the disparity map. In the motion object map generation stage, an adaptive reference frame selection method is introduced to obtain salient motion and produce the motion mask of each view. Experimental results have indicated the good performance and the practicability of the proposed stereo segmentation algorithm.
An Efficient Iridium Catalyst for Reduction of Carbon Dioxide to Methane with Trialkylsilanes (2012)

Cationic silane complexes of general structure (POCOP)Ir(H)(HSiR(3)) {POCOP = 2,6-[OP(tBu)(2)](2)C(6)H(3)} catalyze hydrosilylations of CO(2). Using bulky silanes results in formation of bis(silyl)acetals and methyl silyl ethers as well as siloxanes and CH(4). Using less bulky silanes such as Me(2)EtSiH or Me(2)PhSiH results in rapid formation of CH(4) and siloxane with no detection of bis(silyl)acetal and methyl silyl ether intermediates. The catalyst system is long-lived, and 8300 turnovers can be achieved using Me(2)PhSiH with a 0.0077 mol % loading of iridium. The proposed mechanism for the conversion of CO(2) to CH(4) involves initial formation of the unobserved HCOOSiR(3). This formate ester is then reduced sequentially to R(3)SiOCH(2)OSiR(3), then R(3)SiOCH(3), and finally to R(3)SiOSiR(3) and CH(4).
TELEPHONE SURVEY OF ASAHI SHIMBUN (1996)

The sampling of the ASAHI SHIMBUN telephone survey method was the same as the sampling of the face to face survey method. It was the random selection of samples from the electoral registers. But, as we couldn't know all the telephone numbers of the samples, we couldn't make contact with every sample taken. The respondents to telephone survey were less than those of the face to face survey, especially in young persons and urban dwellers. The representativeness of sample was somewhat inferior to the face to face survey, nevertheless, we think the telephone survey is method effectively measures indicates and the tide of public opinion without delay.
Disrupting the Balance of Protein Quality Control Protein UBQLN2 Accelerates Tau Proteinopathy (2022)

Tau protein accumulation drives toxicity in several neurodegenerative disorders. To better understand the pathways regulating tau homeostasis in disease, we investigated the role of ubiquilins (UBQLNs)-a class of proteins linked to ubiquitin-mediated protein quality control (PQC) and various neurodegenerative diseases-in regulating tau. Cell-based assays identified UBQLN2 as the primary brain-expressed UBQLN to regulate tau. UBQLN2 efficiently lowered wild-type tau levels regardless of aggregation, suggesting that UBQLN2 interacts with and regulates tau protein under normal conditions or early in disease. Moreover, UBQLN2 itself proved to be prone to accumulation as insoluble protein in male and female tau transgenic mice and the human tauopathy progressive supranuclear palsy. Genetic manipulation of UBQLN2 in a tauopathy mouse model demonstrated that a physiological UBQLN2 balance is required for tau homeostasis. UBQLN2 overexpression exacerbated phosphorylated tau pathology and toxicity in mice expressing P301S mutant tau, whereas P301S mice lacking UBQLN2 showed significantly reduced phosphorylated tau. Further studies support the view that an imbalance of UBQLN2 perturbs ubiquitin-dependent PQC and autophagy. We conclude that changes in UBQLN2 levels, whether because of pathogenic mutations or secondary to disease states, such as tauopathy, contribute to proteostatic imbalances that exacerbate neurodegeneration.<b>SIGNIFICANCE STATEMENT</b> We defined a role for the protein quality control protein Ubiquilin-2 (UBQLN2), in age-related neurodegenerative tauopathies. This group of disorders is characterized by the accumulation of tau protein aggregates, which differ when UBQLN2 levels are altered. Given the lack of effective disease-modifying therapies for tauopathies and the function of UBQLN2 in handling various disease-linked proteins, we explored the role of UBQLN2 in regulating tau. We found that UBQLN2 reduced tau levels in cell models but behaved differently in mouse brain, where it accelerated mutant tau pathology and tau-mediated toxicity. A better understanding of the diverse functions of regulatory proteins like UBQLN2 can elucidate some of the causative factors in neurodegenerative disease and outline new routes to therapeutic intervention.
Eddy current pulsed thermography for fatigue evaluation of gear (2014)

The pulsed eddy current (PEC) technique generates responses over a wide range of frequencies, containing more spectral coverage than traditional eddy current inspection. Eddy current pulsed thermography (ECPT), a newly developed non-destructive testing (NDT) technique, has advantages such as rapid inspection of a large area within a short time, high spatial resolution, high sensitivity and stand-off measurement distance. This paper investigates ECPT for the evaluation of gear fatigue tests. The paper proposes a statistical method based on single channel blind source separation to extract details of gear fatigue. The discussion of transient thermal distribution and patterns of fatigue contact surfaces as well as the non-contact surfaces have been reported. In addition, the measurement for gears with different cycles of fatigue tests by ECPTand the comparison results between ECPT with magnetic Barkhausen noise (MBN) have been evaluated. The comparison shows the competitive capability of ECPT in fatigue evaluation.
Search for relativistic magnetic monopoles with the AMANDA-II neutrino telescope (2010)

We present the search for Cherenkov signatures from relativistic magnetic monopoles in data taken with the AMANDA-II detector, a neutrino telescope deployed in the Antarctic ice cap at the Geographic South Pole. The nonobservation of a monopole signal in data collected during the year 2000 improves present experimental limits on the flux of relativistic magnetic monopoles: Our flux limit varies between 3.8 10 -17 cm -2 s -1 sr -1 (for monopoles moving at the vacuum speed of light) and 8.8 10 -16 cm -2 s -1 sr -1 (for monopoles moving at a speed = v/c = 0.76, just above the Cherenkov threshold in ice). These limits apply to monopoles that are energetic enough to penetrate the Earth and enter the detector from below the horizon. The limit obtained for monopoles reaching the detector from above the horizon is less stringent by roughly an order of magnitude, due to the much larger background from down-going atmospheric muons. This looser limit is however valid for a larger class of magnetic monopoles, since the monopoles are not required to pass through the Earth.
50—PRIMARY REACTIONS IN THE PHOTOYELLOWING OF WOOL KERATIN (1976)

After a study of the photochemistry of wool keratin, a mechanism is proposed for the reactions that lead to the sunlight yellowing of wool. The involvement of singlet-excited oxygen is confirmed by both direct and indirect methods.
Effects of Leukotriene D4, the Antagonist L-649-923, and Arachidonic Acid on Duodenal Bicarbonate Secretion in the Rat in Vivo (1988)

Prostaglandins of the E type stimulate bicarbonate secretion by the duodenal mucosa and inhibit gastric acid secretion, effects that have been related to their anti-ulcer activity. Leukotrienes constitute a more recently discovered branch of the arachidonic acid cascade, and C4 and D4 have been suggested to be ulcerogenic in the stomach. We have studied the effects of luminal administration of leukotriene D4 and the leukotriene C4/D4 antagonist L-649-923 on duodenal mucosal alkaline secretion in the anaesthetized rat. Leukotriene D4 (10(-8)-10(-6) M) had no significant effects, but the antagonist dose-dependently increased the bicarbonate secretion and also transiently increased the transmucosal electric potential difference. The precursor arachidonic acid (10(-7)-10(-6) M) caused a small increase in secretion. The increase in bicarbonate secretion in response to 10(-3) M of the antagonist was of about the same magnitude as that observed with 10(-5) of prostaglandin E2, and it was abolished by pretreatment with the cyclooxygenase inhibitor indomethacin. The gastroduodenal protective effects of L-649-923 in vivo may reflect an increase in mucosal prostaglandin production rather than leukotriene antagonism.
Abstract 16349: Revascularization After Ischemia is Partially Mediated by Clonally Expanding Endothelial Cells (2017)

Vascularization is critical to maintain organ function. Outgrowth and clonal expansion of endothelial cells (ECs) has been documented in vitro, however, the contribution of clonally expanding ECs t...
Load balancing on distributed datastore in opendaylight SDN controller cluster (2017)

SDN controller platforms have supported clustering architecture to meet high scalability and availability requirements for large scale carrier grade networks. As a well-known open source project, OpenDaylight provides a clustering and distributed datastore architecture. Datastore is distributed into shards such that a subset of shard can be located in any cluster member. To guarantee strong consistency of datastore that all shard replicas have same value, only the shard leader has responsibility for accepting data updates. Even though OpenDaylight supports a distributed shard leader election algorithm, the elected leaders are not distributed over cluster members due to the lack of centralized control. This results in an unbalanced CPU and network usage of the controller cluster. In this paper, we review the current status of the leader election algorithm for OpenDaylight controller cluster. Then, we propose a shard leader distribution algorithm to fully utilize the distributed datastore. The performance evaluations prove that shard leader distribution enhances the aggregated datastore throughput by distributing the requests for data updates to the distributed datastore.