gebhart/patrepeval huggingface dataset:
Passive Transfer of Immunoglobulin G and Preweaning Health in Holstein Calves Fed a Commercial Colostrum Replacer (2007)

The objective of this study was to describe passive transfer of IgG and preweaning health in newborn calves fed a commercially available plasma-derived colostrum replacement (CR) product or maternal colostrum (MC). Twelve commercial Holstein dairy farms enrolled singleton newborn heifer calves to be fed fresh MC (n = 239 calves) or one dose of CR containing 125 g of Ig (n = 218 calves) as the first colostrum feeding. For 7 of these farms that routinely provided a second feeding of 1.9 L of MC to their calves 8 to 12 h after the first colostrum feeding, calves assigned to the CR treatment group were offered a second feeding consisting of 1.9 L of commercial milk replacer supplemented with one dose of a commercially available plasma-derived colostrum supplement, containing 45 g of Ig per dose, 8 to 12 h after the first colostrum feeding. A blood sample was collected from all calves between 1 to 8 d of age for serum IgG and total protein (TP) determination, and records of all treatment and mortality events were collected until weaning. Serum IgG and TP concentrations were significantly higher in calves fed MC (IgG = 14.8 +/- 7.0 mg/mL; TP = 5.5 +/- 0.7 g/dL) compared with calves fed CR (IgG = 5.8 +/- 3.2 mg/mL; TP = 4.6 +/- 0.5 g/dL). The proportion of calves with failure of passive transfer (serum IgG <10.0 mg/mL) was 28.0 and 93.1% in the MC and CR treatment groups, respectively. Though a trend was present, the proportion of calves treated for illness was not statistically different for calves fed MC (51.9%) vs. CR (59.6%). Total number of days treated per calf (MC = 1.7; CR = 2.0), treatment costs per calf (MC = $10.84; CR = $11.88), and proportion of calves dying (MC = 10.0%; CR = 12.4%) was not different between the 2 colostrum treatment groups. The mean serum total protein concentration predictive of successful passive transfer (serum IgG = 10 mg/mL) was 5.0 g/dL in calves fed MC or CR. Long-term follow-up of these calves (to maturity) is ongoing to describe the effects of feeding CR on longevity, productivity, risk for Johne's disease, and economics.
Trajectron++: Multi-Agent Generative Trajectory Forecasting With Heterogeneous Data for Control (2020)

Reasoning about human motion through an environment is an important
prerequisite to safe and socially-aware robotic navigation. As a result,
multi-agent behavior prediction has become a core component of modern
human-robot interactive systems, such as self-driving cars. While there exist a
multitude of methods for trajectory forecasting, many of them have only been
evaluated with one semantic class of agents and only use prior trajectory
information, ignoring a plethora of information available online to autonomous
systems from common sensors. Towards this end, we present Trajectron++, a
modular, graph-structured recurrent model that forecasts the trajectories of a
general number of agents with distinct semantic classes while incorporating
heterogeneous data (e.g. semantic maps and camera images). Our model is
designed to be tightly integrated with robotic planning and control frameworks;
it is capable of producing predictions that are conditioned on ego-agent motion
plans. We demonstrate the performance of our model on several challenging
real-world trajectory forecasting datasets, outperforming a wide array of
state-of-the-art deterministic and generative methods.
Decreased RBCTs after reduced intensity conditioning allogeneic stem cell transplantation: predictive value of prior Hb level (2004)

Thus, RIC conditioning creates a different pattern of erythropoiesis recovery as compared to a MAC regimen and suggest a need for studies aimed at further reducing RBCT and accelerating Hb recovery.
Holographic patterning of acrylamide-based photopolymer surface (2005)

The patterning of an acrylamide-based photopolymer surface by holographic recording is studied. The patterns are induced by light alone and no post-processing is required. Periodic surface modulation is observed in addition to a volume phase grating. An investigation has been carried out using white light interferometry into the dependence of the amplitude of the photo induced surface relief modulation on the spatial frequency, intensity of recording and sample thickness. The observed dependencies indicate that the diffusion of material during the holographic recording plays a major role in surface relief formation. The possibility for inscription of surface relief patterns opens the door to at least two new applications for this photopolymer: fabrication of diffractive optical elements and biosensors.
Posture-related change in frequency weightings derived from vibration power absorption of the hand-arm system (2011)

The effects of hand-arm on the frequency weightings derived from the vibration power absorption (VPA) of the hand was examined. Five arm posture conditions that consist of two elbow postures, horizontally stretched straight and bent by 90 degrees, in combination with three forearm postures such as pronated, neutral, and supinated, are considered. The experiments were performed with twelve healthy male subjects in their twenties and a single-axis hand-arm vibration test system was used that included an electro-dynamic shaker that can generate vibrations. The vibration signal used in the experiments was a pseudo-random vibration in the frequency range of 10 Hz to 1,250 Hz with a flat power spectrum density (PSD) of 1.0. At frequencies ranging from 40 to 125 Hz, forearm pronation is statistically significant for the neutral/supinated forearm posture. Under the elbow-stretched postures, the VPA-based weighting factors were significantly lower than the ISO weighting factors at frequencies ranging from 12.5 to 1,000 Hz.
Helically chiral poly(quinoxalin-2,3-diyl)s: Toward the synthesis of stereoregular polymeric organocatalysts Part A Polymer chemistry (2009)

The synthesis of seven new aromatic diisocyanide monomers is described and a rationale for their stability is given, as well as their behavior in the palladium-mediated aromatizing polymerization yielding helically chiral poly(quinoxalin-2,3-diyl)s (PQs). Acceleration of the otherwise slow polymerization by microwave heating was observed. The polymers are designed to display potential organocatalytically active functionalities (e.g., phenols, pyridines) nearby stereolabile biaryl axes, which are asymmetrically governed by the configurationally stable helical backbone.
Synthesis of (±)-Rolipram (2006)

Rolipram is a selective inhibitor of phosphodiesterase-4. It is an antiinflammatory agent and an antidepressant. This latest in a long list of syntheses boasts a Pd-catalyzed three-component coupling to generate a vinylboronate intermediate which then undergoes a subsequent Pd-catalyzed carbonylation.
Aortic valve calcifications on chest films: how much calcium do I need? (2011)

Unlike in coronary calcifications, there is a threshold for identifying AVC from conventional chest films. This finding may be of diagnostic value, as conventional chest films may be used to semiquantitatively evaluate the extent of AVC.
Isomolar semigrand ensemble molecular dynamics: Development and application to liquid-liquid equilibria (2005)

An extended system molecular dynamics method for the isomolar semigrand ensemble (fixed number of particles, pressure, temperature, and fugacity fraction) is developed and applied to the calculation of liquid-liquid equilibria (LLE) for two Lennard-Jones mixtures. The method utilizes an extended system variable to dynamically control the fugacity fraction xi of the mixture by gradually transforming the identity of particles in the system. Two approaches are used to compute coexistence points. The first approach uses multiple-histogram reweighting techniques to determine the coexistence xi and compositions of each phase at temperatures near the upper critical solution temperature. The second approach, useful for cases in which there is no critical solution temperature, is based on principles of small system thermodynamics. In this case a coexistence point is found by running N-P-T-xi simulations at a common temperature and pressure and varying the fugacity fraction to map out the difference in chemical potential between the two species A and B (mu(A)-mu(B)) as a function of composition. Once this curve is known the equal-distance/equal-area criterion is used to determine the coexistence point. Both approaches give results that are comparable to those of previous Monte Carlo (MC) simulations. By formulating this approach in a molecular dynamics framework, it should be easier to compute the LLE of complex molecules whose intramolecular degrees of freedom are often difficult to properly sample with MC techniques.
THE PROGRESSION OF EARLY ACTIVITY IN MECHANICALLY VENTILATED PATIENTS IS IMPROVED UPON TRANSFER WITHIN ICUS. (2005)

Bailey, Polly P; Thomsen, George E; Bezdjian, Louise; Spuhler, Vicki; Veale, Kristy; Hopkins, Ramona O Author Information
Retroperitoneal laparoscopic renal biopsy. (1993)

We describe a technique for renal biopsy using laparoscopic guidance. Retroperitoneal laparoscopic dissection and exposure is facilitated by a simple balloon-expanding device made of a rubber glove tied around a catheter. Laparoscopic renal biopsy is associated with less morbidity than open renal biopsy and is ideal when percutaneous renal biopsy is contraindicated or is not feasible.
High-efficiency 5-watt power amplifier with harmonic tuning (2003)

An X-band power amplifier using harmonic tuning and a GaAs FET is described. The amplifier has demonstrated 36% power-added efficiency with 5 W of output power and a 6.0-dB gain at 10 GHz. The key to this design is determining and matching the optimum load impedance for power-added efficiency at the first two harmonics. Nonlinear models were used to study the effects of harmonic tuning and to determine the optimum harmonic terminations. Two amplifiers were designed that demonstrated high-efficiency power amplification at the 0.5-W and 5-W power levels, respectively. The effects of harmonic loading were demonstrated in the 0.5-W amplifier, where the maximum efficiency measured for a device tuned only at the fundamental was 44%, while the measured efficiency of the amplifier with optimum harmonic tuning was 49.3%.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Sequences required for expression of Bordetella pertussis virulence factors share homology with prokaryotic signal transduction proteins. (1989)

The bvg locus of Bordetella pertussis is required for coordinate regulation of several factors associated with virulence. The control system is modulated by various environmental signals, including low temperature, MgSO4, and nicotinic acid. The nucleotide sequence of the bvg region has been determined and three open reading frames, bvgA, bvgB, and bvgC, are present. Twelve-base-pair linker insertion mutations in any of these open reading frames result in a Bvg- phenotype. The predicted protein products of bvgA and bvgC share homology with a family of prokaryotic regulatory proteins that respond to environmental stimuli and are members of two-component sensory transduction systems. We propose a model in which BvgB and the N-terminal portion of BvgC are localized in the periplasm. Environmental signals are recognized, transduced to the cytoplasmic portion of BvgC, and then transmitted to BvgA, a positive regulator of transcription.
Support-Free Porous Polyamine Particles for CO2 Capture (2012)

CO<sub>2</sub> emission from fossil fuel combustion is a major anthropogenic factor for global warming. Solid amine sorbents may be used to remove CO<sub>2</sub> from waste flue gases before their emission into the atmosphere. These particles are currently obtained by loading amine-containing compounds or polymers onto premade or commercially available porous supports. These supports play no active role in CO<sub>2</sub> uptake and increase the amount of heat or cost required to regenerate CO<sub>2</sub>-sorbed particles by heating. Reported in this communication are the preparation, by precipitation polymerization, of support-free polyamine porous particles and the performance of these particles in CO<sub>2</sub> capture at room temperature and release at 100 °C.
The Effect of Casting Conditions on the Fluidity during Lost Foam Casting of Al Alloy (2004)

The effects of casting condition and hot melt glue during Lost Foam Casting were investigated on the fluidity of Al alloy melt. The fluidity increased linearly with increasing pouring temperature in thick castings but non-linearly in thin casting due to the difference in main heat flow direction. The metal flow velocity was in range of cm/s in no evacuation condition and the minimum value of it was measured after the melt flow through the hot melt barrier. The mold evacuation improved the metal flow velocity by around cm/s. And the reaction zone layer thickness was about 1 cm in no-evacuation conditions but about 0.6 cm in mold evacuation condition of 710 torr due to the easier removal of pyrolsis product of EPS. And hot melt barrier thickness of 0.6 mm increased the reaction zone layer thickness up to about 2.5 cm. The fluidity decreased remarkably with an enlarged thickness of hot melt due to a lot of pyrolysis products.
Sensitive terahertz-wave detector responses originated by negative differential conductance of resonant-tunneling-diode oscillator (2020)

We present an experimental characterization of frequency- and bias-dependent detector responses in a resonant-tunneling-diode (RTD) terahertz (THz)-wave oscillator. By tuning the incident THz-wave frequency and the bias voltage applied to the RTD device, the origins of detection signals are identified to be two distinct detection modes. One is based on square-law detection near the peak and valley points of the negative differential conductance (NDC) region, with the detection bandwidth determined by an integrated slot antenna. The other is based on detectable current changes induced by injection locking within the NDC region when the frequency of the incident THz-wave radiation to be detected is coincident with that of the bias-dependent RTD self-oscillation between 0.74 and 0.81 THz, resulting in a minimum noise equivalent power (NEP) of 7.7 pW/√Hz at 0.78 THz at room temperature. Our conclusions demonstrate that an RTD oscillator can be used as a sensitive THz-wave detector within and around the NDC region.
Tantalum Nitride Films Grown by Inorganic Low Temperature Thermal Chemical Vapor Deposition Diffusion Barrier Properties in Copper Metallization (1999)

Key findings are presented from a systematic study which evaluated the performance of chemical vapor deposited (CVD) nitrogenrich tantalum nitride (TaN x , x 1.8) films as a diffusion barrier in copper (Cu) based metallization schemes. For this purpose, 3800 thick Cu films were grown by physical vapor deposition (PVD) on 550 thick TaN x films which were deposited by low temperature (<425C) thermal CVD (TCVD) using tantalum pentabromide (TaBr 5 ), ammonia, and hydrogen as coreactants. The resulting stacks were annealed in argon ambient at 450, 500, 550, and 650C for 30 min each, along with similar PVD Cu/PVD TaN x bilayers of identical thickness. Both types of pre-and postannealed stacks were characterized by X-ray photoelectron spectroscopy, Auger electron spectroscopy, Rutherford backscattering spectrometry, nuclear reaction analysis for hydrogen profiling, X-ray diffraction, stack sheet resistance measurements, and Secco chemical treatment and etch-pit observation by scanning electron microscopy. The resulting findings showed that the PVD TaN x films provided an excellent barrier against Cu diffusion throughout the annealing window investigated. Alternatively, the TCVD TaN x films exhibited similar stability up to 550C. Barrier failure occurred, however, at temperatures between 550 and 600C, as revealed by the formation of etch pits after Secco etch treatment. The failure of the TCVD TaN x films could not be attributed to bromine incorporation, given that residual bromine (0.5 atom %) in the TCVD TaN x films was highly stable against thermal diffusion in the temperature window investigated. Instead, the higher thermal stability of the PVD TaN x was attributed to differences in film microstructure and crystalline phase, or the location of excess nitrogen within the film matrix.
Polymer films as acoustic matching layers (2002)

Polymer films such as polyimide and Parylene were investigated as acoustic matching layers at frequencies in the 100-200-MHz range. Polyimide films were spin coated and Parylene films were vapor deposited on silicon and glass substrates, respectively. The impedance, velocity of sound, and acoustic attenuation of these films were measured. The curing temperature of the polyimide films was also varied to determine the dependence of the material properties on processing conditions. The impedances of these films were measured to be in the 2.7 to 3.7 Mrayl range. The measurements indicate that these films promise good transmission efficiencies between most liquids and especially low impedance solids such as silicon, glass, and quartz.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Correction: Endothelial Expression of Endothelin Receptor A in the Systemic Capillary Leak Syndrome (2015)

The captions for Figs ​Figs11 and ​and22 are switched. The caption that appears with Fig 1 corresponds to Fig 2, and the caption that appears with Fig 2 corresponds to Fig 1. Please see the figures with the appropriate captions below.



Fig 1

Gene expression in BOEC from individual subjects.





Fig 2

Morphology and gene expression in BOEC from SCLS patients and controls.
Major and minor forms of the rat liver asialoglycoprotein receptor are independent galactose-binding proteins. Primary structure and glycosylation heterogeneity of minor receptor forms. (1987)

Preparations of the rat liver asialoglycoprotein receptor (rat hepatic lectin, RHL), which is responsible for the selective uptake of partially deglycosylated serum glycoproteins, have been found to contain multiple polypeptide species. A method has been developed for separating the predominant species (RHL-1) from the minor species (RHL-2/3) using conditions in which RHL-1 retains its galactose-binding activity. Endoglycosidase digestion and lectin blotting have been utilized to demonstrate that RHL-2 and RHL-3 differ by the presence of different carbohydrate structures attached to a common peptide backbone. Antisera specific for RHL-1 and RHL-2/3 have been prepared and utilized to analyze the results of cross-linking experiments performed on purified receptor and hepatocyte membranes. The results show that RHL-1 and RHL-2/3 polypeptides are each associated into homooligomers but are physically unlinked to each other. The structure of the RHL-2/3 polypeptide has been established by protein and cDNA sequence analysis, which reveals that this protein is homologous to RHL-1 throughout its length but contains one major insertion of 18 amino acids near its NH2 terminus. The COOH-terminal portion of the RHL-2/3 polypeptide has been demonstrated to contain a galactose-recognition domain by expression in an in vitro transcription/translation system. The results of these experiments indicate that RHL-1 and RHL-2/3 polypeptides are self-associated into two distinct molecules, each of which has galactose-binding activity.
A recursive hybrid system approach to noise identification (2003)

A hybrid approach that is valid for noise with rapidly or slowly varying statistics as well as constant statistics is presented. This approach is based on estimation using hybrid system models. As one of the most cost-effective estimation schemes for hybrid systems, the interacting multiple model (IMM) algorithm is used. Both simulation results and theoretical evaluation of the proposed approach are given. The approach can also be used for failure detection when failures are characterized by jumps in noise statistics.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Process and operations strategies to enable global access to antibody therapies (2021)

Few monoclonal antibodies are currently approved for treating infectious diseases, but multiple products are in development against a broad range of infectious diseases, including Ebola, influenza, hepatitis B, HIV, dengue, and COVID-19. The maturity of mAb technologies now allow us to identify and advance neutralizing mAb products to the clinic at "pandemic pace", as the pipeline of mAbs targeting SARS-CoV-2 has demonstrated. Ensuring global access to these products for passive immunization, however, will require both low manufacturing cost and multi-ton production capacity-particularly for those infectious diseases where the geographic burden falls mostly in low- and middle-income countries or those with pandemic potential. Analysis of process economics and manufacturing technologies for antibody and other parenteral protein therapeutics demonstrates the importance of economies of scale to reducing the cost of goods for drug substance manufacturing. There are major benefits to convergence on a standardized platform process for antibody production that is portable to most existing very large-scale facilities, carries low risk for complications during process transfer and scale-up, and has a predictable timeline and probability of technical and regulatory success. In the case of an infectious disease with pandemic potential which could be treated with an antibody, such as COVID-19 or influenza, these advantages are paramount.
Transabdominal Ultrasound Versus Excretory Urography in Preoperative Evaluation of Patients with Prostatism (1987)

Transabdominal ultrasound is superior to excretory urography when radiographic imaging of the urinary tract is indicated in patients with prostatism. We studied 53 patients with excretory urography and ultrasonography before prostatectomy. Patients with a history of microscopic or macroscopic hematuria, urolithiasis, renal failure or upper urinary tract anomalies were excluded from our study. Ultrasonography proved to be more accurate in defining prostatic size and configuration. Bladder wall thickness also was quantified more clearly with ultrasonography. We found 17 renal masses incidentally with excretory urography, although ultrasound was essential and superior to excretory urography in defining these masses in each case. We recommend that ultrasonography be used in lieu of excretory urography when imaging of the urinary tract is indicated before prostatectomy.