gebhart/patrepeval huggingface dataset:
Robust visual servoing: bounding the task function tracking errors (2005)

This article deals with the well known problem of robust visual servoing (VS), which is formulated by the use of the general task function approach. Robustness is provided with respect to calibration parametric errors not only in terms of stability, but also in terms of tracking errors boundness. As a result, the proposed approach allows the user to choose a bound on the tracking error so as to guarantee the visibility of the target during the task execution. Most importantly, the error boundness is obtained while avoiding the use of large gains. Rather, one uses bounded gains, together with the modulation of the desired velocity along the desired path. An application of this general approach is developed and experimentally validated.
Hip Screw Augmentation with an In Situ-Setting Calcium Phosphate Cement: An In Vitro Biomechanical Analysis (1997)

The in situ-setting calcium phosphate cement investigated in this study compared favorably with PMMA in a single-cycle cut-out test of augmented compression hip screws in senile trabecular bone. Our results suggest that these materials may have promise as substitutes for PMMA in the salvage of compression hip screw fixation in elderly osteopenic patients with complex intertrochanteric fractures and that further study of their use in this application is warranted.
Fabrication and characterization of zirconium cross-linked carboxymethyl cellulose-chitosan microparticles for bone tissue engineering application (2016)

Frontiers Events is a rapidly growing calendar management system dedicated to the scheduling of academic events. This includes announcements and invitations, participant listings and search functionality, abstract handling and publication, related events and post-event exchanges. Whether an organizer or participant, make your event a Frontiers Event!
ChemInform Abstract: Facile Construction of the Tricyclo[5.2.1.01,5]decane Ring System by Intramolecular Double Michael Reaction: Highly Stereocontrolled Total Synthesis of (.+‐.)‐8,14‐Cedranediol and (.+‐.)‐8,14‐Cedranoxide. (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Immunochemical Measurement of the Vitamin D-Binding Protein in Rat Serum* (1978)

The vitamin D-binding protein (DBP) was measured in rat serum using a single radial immunodiffusion technique. Normal serum levels at birth (74 ± 11 mg/liter, mean ± SD) were lower than during the last day of fetal life (130 ± 14 mg/liter) and much lower than in adult rats. A marked sex difference in DBP occurred after puberty: male values (656 ± 52 mg/liter) were significantly higher than female values (472 ± 46 mg/liter). The sex difference could be abolished by either adult gonadectomy or transpharyngeal hypophysectomy. Implantation of a pituitary gland under the renal capsule in hypophysectomized male rats further decreased the DBP concentration, suggesting that PRL suppresses the DBP level. A similar decrease was also observed at the end of pregnancy and during lactation. Administration of androgens to either normal female or gonadectomized male rats increased their DBP concentration to the normal adult male level. The serum levels of total 25-hydroxyvitamin D did not fluctuate according to the concentration of DBP, indicating that the concentration of “free 25-hydroxyvitamin D” is not regulated at a constant level. (Endocrinology102: 1710, 1978)
Cation radical Diels-Alder reactions of electron-rich dienophiles (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCation radical Diels-Alder reactions of electron-rich dienophilesRaul A. Pabon, Dennis J. Bellville, and Nathan L. BauldCite this: J. Am. Chem. Soc. 1983, 105, 15, 5158–5159Publication Date (Print):July 1, 1983Publication History Published online1 May 2002Published inissue 1 July 1983https://pubs.acs.org/doi/10.1021/ja00353a065https://doi.org/10.1021/ja00353a065research-articleACS PublicationsRequest reuse permissionsArticle Views1034Altmetric-Citations103LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Empiric antibiotic selection strategies for healthcare‐associated pneumonia, intra‐abdominal infections, and catheter‐associated bacteremia (2012)

Initial selection and early deployment of appropriate/adequate empiric antimicrobial therapy is critical to minimize the significant morbidity and mortality associated with hospital- or healthcare-associated infections (HAIs). Initial empiric therapy that inadequately covers the pathogen(s) causing a serious HAI has been associated with increased mortality, longer hospital stay, and elevated healthcare costs. Moreover, subsequent modification of initial inadequate therapy, later in the disease process when culture results become available, may not remedy the impact of the initial choice. Because of this, it is important that initial empiric therapy covers the most likely pathogens associated with infection in a particular patient, even if this initial regimen turns out to be unnecessarily broad, based on subsequent culture results. The current paradigm for management of serious HAIs is to initiate empiric therapy with a broad-spectrum regimen covering likely pathogens, based on local surveillance and susceptibility data, and presence of risk factors for involvement of a resistant microorganism. Subsequent modification (de-escalation) of the initial regimen becomes possible later, when culture results are available and clinical status can be better assessed, 2 to 4 days after initiation of empiric therapy. When possible, de-escalation and other steps to modify antimicrobial exposure are important for minimizing risk of antimicrobial resistance development. This article examines the general process for selection of initial empiric antibiotic therapy for patients with HAIs, illustrated through 3 case studies dealing with healthcare-associated pneumonia, complicated intra-abdominal infection, and catheter-associated bacteremia, respectively. Journal of Hospital Medicine 2012;7:S2-S12. © 2012 Society of Hospital Medicine.
Pd(ii)-catalyzed direct functionalization of C–H bonds of benzamides for synthesis of 1,1-difluoro-1-alkenes (2016)

Pd-catalyzed difluoroallylation of unactivated C(sp<sup>2</sup>)–H bonds with readily available R<sub>f</sub>-Br reagents is described.
Cutting Edge: PHLPP Regulates the Development, Function, and Molecular Signaling Pathways of Regulatory T Cells (2011)

Regulatory T cells (Tregs) have a reduced capacity to activate the PI3K/Akt pathway downstream of the TCR, and the resulting low activity of Akt is necessary for their development and function. The molecular basis for the failure of Tregs to activate Akt efficiently, however, remains unknown. We show that PH-domain leucine-rich-repeat protein phosphatase (PHLPP), which dephosphorylates Akt, is upregulated in Tregs, thus suppressing Akt activation. Tregs expressed higher levels of PHLPP than those of conventional T cells, and knockdown of PHLPP1 restored TCR-mediated activation of Akt in Tregs. Consistent with their high Akt activity, the suppressive capacity of Tregs from PHLPP1(-/-) mice was significantly reduced. Moreover, the development of induced Tregs was impaired in PHLPP1(-/-) mice. The increased level of Akt's negative regulator, PHLPP, provides a novel mechanism used by T cells to control the Akt pathway and the first evidence, to our knowledge, for a molecular mechanism underlying the functionally essential reduction of Akt activity in Tregs.
EL MATERIAL HALLSTATTICO DE LA CUEVA DE LA BORA TUNA DE LLORA, GERONA (1975)

Revista especializada en la publicación de trabajos originales de investigación en Prehistoria y Arqueología. Es la publicación periódica más antigua de la UAM. Su enfoque abierto a cualquier temática y época pasada, hasta la más cercana, que sea objeto de la Ciencia arqueológica se abre a una decidida proyección internacional en la que quiere basar su futuro inmediato.
Single-Port Extraperitoneal Robot Assisted Radical Prostatectomy – Description of Technique (2022)

Objective: The novel single-port (SP) platform offers an alternative way to perform robot-assisted radical prostatectomy (RARP). The SP platform allows operating in small anatomical spaces. Using this benefit, we adopted the extraperitoneal approach to RARP. Herein, we aim to describe our technique to perform SP extraperitoneal RARP. Patients and Surgical Procedure: We demonstrate the video of a 55-year-old man with a PSA of 4.4 ng/ml. Biopsy showed 5/13 cores positive for Gleason 3+3 prostate cancer. Preoperative prostate MRI showed a 43 g prostate and a right to midline anterior 1.8 cm PI-RADS 5 lesion, with possible extracapsular extension. We performed an extraperitoneal SP RARP and bilateral pelvic lymph node dissection. Results: The case was completed in 3 hours and 11 minutes. Estimated blood loss was 100 ml. Patient was discharged 8 hours after surgery. Pathology revealed pT2N0 stage and Gleason 3+4 prostate cancer. At 3 months follow up, PSA was undetectable and patient was continent. We performed 212 cases using this approach. Surgery was successfully completed in all patients without any need for additional port placement. Median length of stay was 4 hours, and 62 patients were admitted for observation. 50.5% of patients did not require opioid analgesics after discharge. Among patients with available one year follow data, 92.2% were continent and 85.9% had undetectable PSA. Conclusion: Extraperitoneal SP RARP can be safely performed using the novel SP surgical platform.
Manufacturing of High-Concentration Monoclonal Antibody Formulations via Spray Drying--the Road to Manufacturing Scale (2015)

This study evaluates a pilot-scale spray dryer against a laboratory-scale dryer to spray-dry multiple monoclonal antibodies (mAbs) from the perspective of scale-up, impact on mAb stability, and feasibility of a high-concentration preparation. The data demonstrated that there is no process limitation in solution viscosity when high-concentration mAb formulations are prepared from spray-dried powder reconstitution compared with concentration via the conventional ultrafiltration process. This study offers a commercially viable spray-drying process for biological bulk storage and a high-concentration mAb manufacturing option for subcutaneous administration. The outcomes of this study will benefit scientists and engineers who develop high-concentration mAb products by providing a viable manufacturing alternative.
Characteristics of sixteen mung bean cultivars and their protein isolates (2010)

Summary Sixteen mung bean varieties were studied for their proximate composition and protein isolates’ properties. A wide range of variation was observed: crude protein content ranged 24.26–28.50%, crude fibre 3.21–4.18%, crude fat 0.57–1.86%, ash content 3.64–4.24%, moisture 7.49–8.45% and carbohydrates 54.25–58.69%, respectively. The content of protein, ash, fat and moisture in isolated proteins ranged from 69.22% to 74.85%, 2.19% to 3.04%, 0.36% to 0.64% and 8.20% to 9.28%, respectively. The functional properties of isolated proteins analysed including water absorption capacity, oil absorption capacity, foaming capacity, foam stability, emulsifying activity and protein solubility, which ranged from 1.03 g g −1 to 2.78 g g −1 , 1.00 mL g −1 to 3.38 mL g −1 , 33.00% to 67.50%, 56.00% to 20.00%, 1.77 m 2 g −1 to 3.30 m 2 g −1 and 28.7% to 65.52%, respectively. Properties of mung bean protein isolates except oil absorption capacity were similar to most of legumes’ but lower than soybean’s. Oil absorption capacity showed negative correlation with nitrogen solubility index.
A Critical Review on Al-Co Alloys: Fabrication Routes, Microstructural Evolution and Properties (2022)

Al-Co alloys is an emerging category of metallic materials with promising properties and potential application in various demanding environments. Over the years, different manufacturing techniques have been employed to fabricate Al-Co alloys, spanning from conventional casting to rapid solidification techniques, such as melt spinning, thus leading to a variety of different microstructural features. The effect of the fabrication method on the microstructure is crucial, affecting the morphology and volume of the precipitates, the formation of supersaturated solid solutions and the development of amorphous phases. In addition, the alloy composition has an effect on the type and volume fraction of intermetallic phases formed. As a result, alloy properties are largely affected by the microstructural outcomes. This review focuses on highlighting the effect of the fabrication techniques and composition on the microstructure and properties of Al-Co alloys. Another goal is to highlight areas in the field that are not well understood. The advantages and limitations of this less common category of Al alloys are being discussed with the scope of future prospects and potential applications.
Structure and Function of BRCA Genes (2000)

The BRCA1 and BRCA2 genes fit the traditional description of tumor-suppressor genes, according to Knudson’s classic two-hit model (1,2). In familial cancers, an individual inherits a germline mutation, and thus this first hit is present in all cells of the body. A somatic mutation represents the second hit on a given cell, resulting in the loss of the wild-type (WT) allele, thus rendering both copies of the gene inactive (3,4). In sporadic cancers, loss of function of a tumor-suppressor gene is accomplished by two somatic mutations that alter the alleles on both chromosomes (chrs). Knudson’ s model accurately accounts for the early onset of familial cancers caused by a pre-existing germline mutation; the accumulation of two somatic mutations in a single cell, a much less likely event, may occur once in several decades, giving rise to a sporadic cancer.
Improved Survival of Asians With Corpus Cancer Compared With Whites (2006)

II-2.
A stochastic geometry based performance analysis framework for massive MIMO systems with data-assisted uplink detection scheme (2015)

It has been shown in the existing literature that the data symbols can assist the massive MIMO transmission by relieving the issue of pilot contamination. In order to further evaluate the performance gain from system point of view, a stochastic geometry based framework is established in this paper to analyze the distribution of signal-to-interference ratio in a massive MIMO cellular network with data-assisted uplink detection scheme. The closed-from expressions of the asymptotic performance bounds are thereby derived. It is shown by numerical simulation that the analytical bounds fit the real performance with high accuracy.
Dynamic and Control of an Absorber - Desorber Plant at Heilbronn (2017)

The present work is based on an MEA absorption test campaign performed November 2013–January 2014 at EnBW's amine test pilot located in Heilbronn, Germany. The test campaign included transient step responses in steam, exhaust gas, solvent flow rate and in exhaust gas CO2 concentration. In addition, a test with simultaneous steps in all flow rates (exhaust gas, solvent and steam) was included. A dynamic model of the Heilbronn plant was then implemented in the dynamic simulator K-Spice® and tested against the step responses at the plant. In spite of some stead state deviations, the model was able to capture the process dynamics very well. For dynamic studies one can therefore assume that the model is representative for the plant. In the work presented here, two different control configurations were tested: 1) Ratio control in combination with a slow feed back control on the CO2 out of the absorber and 2) Control of CO2 out of the absorber by lean liquid flow rate and a temperature sensor up in the desorber packing. Both structures involve only simple PID control loops and are thus easy to implement. The proposed control configurations were tested by simulations with 30% changes in flue gas flow and composition. Both configurations showed good performance during the simulation testing, but the second one was superior as well as excellent with respect to tight CO2 recovery control. This may be an important property in supervisory control schemes.
The influence of Assembly ergonomics on product quality and productivity in car manufacturing - a cost-benefit approach (2008)

The influence of assembly ergonomics on product quality in car manufacturing – a cost-benefit approach Car manufacturing is often associated with poor working environment resulting in musculoskeletal disorders and high sick leave among assembly workers. Besides, a number of studies have proven that there is a clear correlation between assembly ergonomics and product quality and that poor assembly ergonomics result in impaired product quality and in increased production costs. Many proactive measures have been made trying to prevent these problems such as training production staff in load ergonomics, workstation improvements and design changes in product and production development. Nevertheless, there are remaining difficulties in receiving acceptance for product and production changes because of poor assembly ergonomics solutions. This project aims at analyzing the correlation between assembly ergonomics, assemblability and product quality. The objective is to quantify ergonomics and assemblability in economic terms in order to better support product and assembly solutions during the early development process of new car models. Overall, the purpose is to create a tool that supports decision making in the design of assembly concepts. The tool will have functionality to assess ergonomic conditions in terms of quality and productivity, interpreted in monetary terms.A selection of assemblies of high, medium and low ergonomic risk level will be followed and evaluated with respect to quality errors for eight weeks. The number of quality errors will be registered both in the assembly plant and on the after-sales market. The costs for scrap and corrective quality actions will be calculated both in the plant and on the after-sales market. The purpose is to define a quality cost associated to each ergonomic risk issue.
Diffusion tensor imaging in fixed brain tissue at 7.0 T (2003)

The purpose of this work is to assess the feasibility of performing quantitative in vitro brain tissue diffusion tensor imaging (DTI) measurements and to examine their comparability to in vivo measurements. DTI of fixed tissue at high field strength is potentially a very valuable investigative tool as very high spatial resolution can be achieved. DTI was applied to human and mouse brain fixed tissue samples as well as in vivo measurements of the mouse brain. T(1) and T(2) relaxography of the fixed tissue samples was also performed to provide further characterization of the tissue. All experiments were performed at 7 T. The fractional anisotropy (FA) of the human fixed brain tissue samples is found to be higher in the corpus callosum than in the occipital white matter region, consistent with in vivo measurements reported in the literature. Our FA measurements of the corpus callosum of a mouse brain are also found to be the same both in vitro and in vivo. This preliminary work supports the use of DTI in both fixed human and fixed animal brain tissue as a valid investigative tool. With the increased availability of brain banks in different brain disorders, DTI in fixed tissue may prove to be a very useful method for the study of white matter abnormalities.
Coating induced phase shift and impact on Euclid imaging performance (2016)

The challenging constraints imposed on the Euclid telescope imaging performances have driven the design, manufacturing and characterisation of the multi-layers coatings of the dichroic. Indeed it was found that the coatings layers thickness inhomogeneity will introduce a wavelength dependent phase-shift resulting in degradation of the image quality of the telescope. Such changes must be characterized and/or simulated since they could be non-negligible contributors to the scientific performance accuracy. Several papers on this topic can be found in literature, however the results can not be applied directly to Euclid’s dichroic coatings. In particular an applicable model of the phase-shift variation with the wavelength could not be found and was developed. The results achieved with the mathematical model are compared to experimental results of tests performed on a development prototype of the Euclid’s dichroic.
Pericytes from Mesenchymal Stem Cells as a model for the blood-brain barrier (2017)

Blood brain-barrier (BBB) in vitro models have been widely reported in studies of the BBB phenotype. However, established co-culture systems involve brain endothelial cells, astrocytes, neurons and pericytes, and therefore are often consuming and technically challenging. Here we use mesenchymal system cells (MSC) as a potential substitute for pericytes in a BBB model. Both MSC and pericyte markers in 2D culture environment were evaluated on different extracellular matrix compositions. Further experiments indicated that MSC contributed in a similar manner to pericytes in a co-cultured 3D model on increasing trans-endothelial electric resistance (TEER) and decreasing permeability against macromolecules.
Additive pulse mode-locked NaCl:OH - laser (1989)

The operation of an additive-pulse mode-locked NaCl:OH− color-center laser is described. Stable output pulses as short as 75 fsec have been obtained. The laser is tunable from 1.51 to 1.65 μm, with 300 mW of average output power at 1.6 μm.