gebhart/patrepeval huggingface dataset:
Integrons and Gene Cassettes in the Enterobacteriaceae (2001)

Integrons were detected in 59 of 120 (49%) urinary isolates of Enterobacteriaceae by PCR using degenerate primers targeted to conserved regions of class 1, 2, and 3 integrase genes. PCR sequencing analysis of the cassette arrays revealed a predominance of cassettes that confer resistance to the aminoglycosides and trimethoprim.
ChemInform Abstract: Iron‐Catalyzed Enantioselective Reactions Through the Use of Chiral Bipyridine‐Containing Ligands (2013)

Abstract Review: 20 refs.
Uncertainty in linewidth quantification of overlapping Raman bands (2019)

Spectral linewidths are used to assess a variety of physical properties, even as spectral overlap makes quantitative extraction difficult owing to uncertainty. Uncertainty, in turn, can be minimized with the choice of appropriate experimental conditions used in spectral collection. In response, we assess the experimental factors dictating uncertainty in the quantification of linewidth from a Raman experiment highlighting the comparative influence of (1) spectral resolution, (2) signal to noise, and (3) relative peak intensity (RPI) of the overlapping peaks. Practically, Raman spectra of SiGe thin films were obtained experimentally and simulated virtually under a variety of conditions. RPI is found to be the most impactful parameter in specifying linewidth followed by the spectral resolution and signal to noise. While developed for Raman experiments, the results are generally applicable to spectroscopic linewidth studies illuminating the experimental trade-offs inherent in quantification.
Dipole-Coil-Based Wide-Range Inductive Power Transfer Systems for Wireless Sensors (2016)

A dipole-coil-based extremely loosely coupled inductive power transfer system (IPTS) for wireless sensors over a wide range is proposed. The overall superiority of dipole coils for a long-distance power delivery over loop coils with an identical configuration of a square core is verified by comparing the magnetizing inductance between primary and secondary coils. Series-parallel resonant circuits were used to achieve a higher load voltage than that of the series-series scheme. Contrary to conventional IPTSs or coupled magnetic resonance systems, the quality factor Q was set as low as 100, guaranteeing a frequency tolerance of 1%, where a prototype of narrow dipole coils with a length of 2 m was used to deliver 10.3 W of power up to 7 m away at a low frequency of 20 kHz. The powering capabilities of the proposed IPTS were experimentally compared inside and outside of a metal container 8 m × 4 m × 2.5 m in size at different frequencies ranging from 20 to 150 kHz, where the proposed IPTS is highly likely to be surrounded by arbitrary distributed conductors in most wireless sensor usage environments. The coupling coefficient κ between the primary and secondary coils was measured over a long distance from 2 to 12 m for different secondary coil positions, where κ is mostly much less than 0.01. A comparative analysis of the maximum amounts of load power among different core materials, i.e., two ferrite cores and an amorphous core, was conducted in relation to the design of a secondary coil. The results were verified by experiments at a given switching frequency of 20 kHz.
Transgenic apple plants overexpressing the chalcone 3-hydroxylase gene of Cosmos sulphureus show increased levels of 3-hydroxyphloridzin and reduced susceptibility to apple scab and fire blight (2016)

Overexpression of chalcone-3-hydroxylase provokes increased accumulation of 3-hydroxyphloridzin in Malus . Decreased flavonoid concentrations but unchanged flavonoid class composition were observed. The increased 3-hydroxyphlorizin contents correlate well with reduced susceptibility to fire blight and scab. The involvement of dihydrochalcones in the apple defence mechanism against pathogens is discussed but unknown biosynthetic steps in their formation hamper studies on their physiological relevance. The formation of 3-hydroxyphloretin is one of the gaps in the pathway. Polyphenol oxidases and cytochrome P450 dependent enzymes could be involved. Hydroxylation of phloretin in position 3 has high similarity to the B-ring hydroxylation of flavonoids catalysed by the well-known flavonoid 3'-hydroxylase (F3'H). Using recombinant F3'H and chalcone 3-hydroxylase (CH3H) from Cosmos sulphureus we show that F3'H and CH3H accept phloretin to some extent but higher conversion rates are obtained with CH3H. To test whether CH3H catalyzes the hydroxylation of dihydrochalcones in planta and if this could be of physiological relevance, we created transgenic apple trees harbouring CH3H from C. sulphureus. The three transgenic lines obtained showed lower polyphenol concentrations but no shift between the main polyphenol classes dihydrochalcones, flavonols, hydroxycinnamic acids and flavan 3-ols. Increase of 3-hydroxyphloridzin within the dihydrochalcones and of epicatechin/catechin within soluble flavan 3-ols were observed. Decreased activity of dihydroflavonol 4-reductase and chalcone synthase/chalcone isomerase could partially explain the lower polyphenol concentrations. In comparison to the parent line, the transgenic CH3H-lines showed a lower disease susceptibility to fire blight and apple scab that correlated with the increased 3-hydroxyphlorizin contents.
A sampling theorem for Manhattan grids (2012)

This paper presents a sampling theorem for Manhattan-grid sampling, which is a sampling scheme in which data is taken along evenly spaced rows and columns. Given the spacing between the rows, the columns, and the samples along the rows and columns, the theorem shows that an image can be perfectly reconstructed from Manhattan-grid sampling if its spectrum is bandlimited to a cross-shaped region whose arm lengths and widths are determined by the aforementioned sample spacings. The nature of such cross-bandlimited images is demonstrated by filtering an image with a cross-bandlimiting filter for several choices of sampling parameters.
Navier-stokes, fluid dynamics, and image and video inpainting (2005)

Image inpainting involves filling in part of an image or video using information from the surrounding area. Applications include the restoration of damaged photographs and movies and the removal of selected objects. We introduce a class of automated methods for digital inpainting. The approach uses ideas from classical fluid dynamics to propagate isophote lines continuously from the exterior into the region to be inpainted. The main idea is to think of the image intensity as a 'stream function for a two-dimensional incompressible flow. The Laplacian of the image intensity plays the role of the vorticity of the fluid; it is transported into the region to be inpainted by a vector field defined by the stream function. The resulting algorithm is designed to continue isophotes while matching gradient vectors at the boundary of the inpainting region. The method is directly based on the Navier-Stokes equations for fluid dynamics, which has the immediate advantage of well-developed theoretical and numerical results. This is a new approach for introducing ideas from computational fluid dynamics into problems in computer vision and image analysis.
A New App for At-Home Cognitive Training: Description and Pilot Testing on Patients with Multiple Sclerosis (2015)

As COGNI-TRAcK is highly usable, motivating, and well-accepted by patients with MS, its effectiveness can now be investigated. To improve COGNI-TRAcK, new releases should contain more working memory exercises, have enhanced perceived amusement, and promote Internet communication procedures for data transfer and fostering remote control of the intervention.
Modeling BJT radiation response with non-uniform energy distributions of interface traps (2000)

Radiation-induced oxide defects that degrade electrical characteristics of BJTs can be measured with the use of gated diodes. The buildup of defects and their effect on device radiation response are modeled with computer simulation.
Oral Supplementation of Butyrate Reduces Mucositis and Intestinal Permeability Associated with 5‐Fluorouracil Administration (2012)

Mucositis affects about 40 % of patients undergoing chemotherapy. Short chain fatty acids (SCFA), mainly butyrate, are claimed to improve mucosal integrity, reduce intestinal permeability and act as anti-inflammatory agents for the colon mucosa. We evaluated the effects of oral administration of SCFA or butyrate in the 5FU-induced mucositis. Mice received water, SCFA or butyrate during all experiment (10 days) and a single dose of 5FU (200 mg/kg) 3 days before euthanasia. We evaluated inflammatory and histological score by morphometry, and by activity of enzymes specific to neutrophil, eosinophil and macrophage and TLR-4, TNF-alpha and IL6 expressions. Intestinal permeability and tight junction protein ZO-1 expression were evaluated. Mice from the 5FU (5-Fluorouracil) group presented weight loss, ulcerations and inflammatory infiltration of neutrophils and eosinophils, increased expression of IL6 and TNF-alpha and increased intestinal permeability. SCFA minimized intestinal damage, reduced ulcerations without affecting intestinal permeability. Butyrate alone was more efficient at improving those parameters than in SCFA solution and also reduced intestinal permeability. The expression of pro-inflammatory cytokines and ZO-1 tended to be higher in the SCFA supplemented but not in the butyrate supplemented group. We showed the beneficial effects of butyrate on intestinal mucositis and its promising function as an adjuvant in the treatment of diseases not only of the colon, but also of the small intestine.
Temporal and Spatial Variations in Structural Protein Expression During the Progression From Stunned to Hibernating Myocardium (2004)

Qualitative cardiomyocyte remodeling similar to that in humans with chronic hibernation occurs rapidly after a critical coronary stenosis is applied, as well as after transient elevations in left ventricular end-diastolic pressure in the absence of ischemia. Thus, reorganization of cytoskeletal proteins in patients with viable dysfunctional myocardium appears to reflect chronic and/or cyclical elevations in preload associated with episodes of spontaneous regional ischemia.
The Effects of Lipoxin A 4 on Airway Responses in Asthmatic Subjects (1992)

This study was performed to determine whether lipoxin A4 (LXA4) inhalation in asthmatic subjects has an effect on airways response. Eight subjects (six asthmatic, two normal) attended for bronchial inhalation challenge with LXA4. In three of these subjects (two asthmatics, one normal) blood pressure, pulse, and symptoms before and after challenge were recorded. Subsequently five male patients with mild asthma (22 to 34 yr of age) reattended for bronchial inhalation challenge with either leukotriene C4 (LTC4) or the combination of LTC4 and 1 x 10(-4) M LXA4. After inhalation of each dose of agonist SGaw and V25 were measured. Airway responsiveness was determined by the concentration of agonist in the nebulizer required to induce a 35% fall in SGaw (PC35). There was no effect of LXA4 inhalation on SGaw, V25, blood pressure, pulse, or symptoms. There was a significant shift of the SGaw and V25 dose-response curve to the right after inhalation challenge with LTC4 combined with 1 x 10(-4) M LXA4 as compared with that after inhalation challenge with LTC4 alone (p less than 0.01 and p less than 0.025, respectively). Thus, LXA4 may modulate LTC4-induced airway obstruction and may act as an endogenous sulfidopeptide leukotriene receptor antagonist.
Dember and photo-electromotive-force currents in silicon photoconductive detectors (2004)

Dember and photo-electromotive-force (PEMF) currents are investigated in silicon photoconductive detectors both theoretically and experimentally. Dember photocurrents were found to dominate the response of high-purity silicon samples with top-surface electrodes to a moving interference pattern. The use of surface electrodes leads to shadowed regions beneath the electrodes, and Dember photocurrents appear under short-circuit conditions. A single-charge-carrier model of the Dember effect is in good qualitative agreement with experimental results. We also show theoretically that the PEMF effect in silicon is weak compared with other semiconductors because of its relatively high intrinsic conductivity.
Neuro-fuzzy controller and convention controller: a comparison (2003)

This paper discusses connections between the PID and adaptive controller with a neuro-fuzzy controller (NEFCON). The advantages and disadvantages of NEFCON are discussed. The results of this paper apply to a two-link robotic arm. The computer simulation shows that this technique is superior to conventional control techniques including PID and adaptive controllers.
Novelties and records of poroid Basidiomycetes in Finland and adjacent Russia (2001)

Leningrad Region, Russia; this is the second find of the species after its description from Siberia. Junghuhnia fimbriate/la (Peck) RyYarden was found in Leningrad Region; this is the first record in northern Europe. Skeletocutis borealis Niemela and many other rare species are discussed, including new localities from Finland and/or NW Russia. Some of them are illustrated, and many species are supplied w ith detailed spore measurements. 143 polypore species were recorded and collected by the authors and their co-workers in virgin forests of Russian Karelia in wide sense; 12 of them are new to the area.
Metabolic Regulation of Renal Gluconeogenesis in Response to Sepsis in the Rat (1990)

1. The regulation of renal gluconeogenesis was studied in rats made septic by a caecal ligation and puncture technique. 2. Blood glucose concentrations were not markedly different in septic rats, but lactate, pyruvate and alanine concentrations were markedly increased, compared with sham-operated rats. Conversely, blood ketone body concentrations were significantly decreased in septic rats. Both plasma insulin and glucagon concentrations were markedly elevated in response to sepsis. 3. The maximal activities of glucose-6-phosphatase (EC 3.1.3.9), fructose-1,6-bisphosphatase (EC 3.1.3.11), pyruvate carboxylase (EC 6.4.1.1) and phosphoenolpyruvate carboxykinase (EC 4.1.1.49) were markedly decreased in kidneys obtained from septic rats, suggesting diminished renal gluconeogenesis. 4. Renal concentrations of lactate, pyruvate and other gluconeogenetic intermediates were markedly elevated in septic rats, whereas those of acetyl-CoA and fructose 2,6-bisphosphate were decreased and unchanged, respectively. 5. The rate of gluconeogenesis from added lactate, pyruvate and glycerol was decreased in isolated incubated renal tubules from septic rats. 6. Sepsis decreased the arteriovenous concentration difference for glucose, lactate, and alanine. Septic rats showed decreased net rates of glucose production and net rates of removal of lactate and alanine as compared with sham-operated controls. 7. It is concluded that the diminished capacity for renal gluconeogenesis in septic rats could be the result of changes in the maximal activities or regulation of key non-equilibrium gluconeogenic enzymes or both, but the effect of other factors (e.g. toxins) has not been excluded.
Bright light and high density negative air ionisation reduced symptoms in seasonal affective disorder (1999)

Terman M, Terman JS, Ross DC. A controlled trial of timed bright light and negative air ionization for treatment of winter depression. Arch Gen Psychiatry1998 Oct; 55 : 875 –82 [OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4] Question In patients with seasonal affective disorder (SAD), do timed bright light and negative air ionisation reduce symptoms? Randomised, morning by evening light crossover trial balanced by parallel group controls, in addition to a non-photic control (negative air ionisation), with follow up to 4 weeks. Psychiatry department in New York, New York, USA. 158 patients between 18 and 65 years of age who were recruited through media and physician referrals with a DSM-III-R diagnosis of SAD. Exclusion criteria included other Axis I disorders, suicide attempt within the previous 3 years, and habitual sleep onset later than 1 am or awakening later than 9 am. 145 patients (92%) completed the study. Patients were allocated to 6 groups for 2 consecutive treatment periods, each lasting 10–14 days. 2 parallel groups received morning treatment with negative ions. 4 groups received light treatment and were crossed over at mid point using the following sequences: morning-evening, evening-morning, morning-morning, and evening-evening (10 000 lux, 30 min/d). 2 groups received negative air ionisation treatment at either high density (2.7 x 106) or low density (serving as the placebo control, 1.0 x 104 per cubic … [1]: {openurl}?query=rft.jtitle%253DArchives%2Bof%2BGeneral%2BPsychiatry%26rft.stitle%253DArch%2BGen%2BPsychiatry%26rft.aulast%253DTerman%26rft.auinit1%253DM.%26rft.volume%253D55%26rft.issue%253D10%26rft.spage%253D875%26rft.epage%253D882%26rft.atitle%253DA%2BControlled%2BTrial%2Bof%2BTimed%2BBright%2BLight%2Band%2BNegative%2BAir%2BIonization%2Bfor%2BTreatment%2Bof%2BWinter%2BDepression%26rft_id%253Dinfo%253Adoi%252F10.1001%252Farchpsyc.55.10.875%26rft_id%253Dinfo%253Apmid%252F9783557%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.1001/archpsyc.55.10.875&link_type=DOI [3]: /lookup/external-ref?access_num=9783557&link_type=MED&atom=%2Febmental%2F2%2F3%2F87.atom [4]: /lookup/external-ref?access_num=000076415500004&link_type=ISI
ChemInform Abstract: ACENAPHTHEN‐DERIVATE 26. MITT. THERMISCHE CYCLOADDITION VON 2‐DIAZOACENAPHTHENON AN ISOCYANATE (1973)

Abstract Während bei der Behandlung der Titelverbindung (I) mit Phenyl‐isocyanat oder ‐isothiocyanat in Toluol unter Rückflußkochen keine Umsetzung stattfindet, reagiert (I) mit den stärker elektrophilen Acylisocyanaten und ‐isothiocyanaten (II) zu den Heterospiranen (III); unter analogen Bedingungen liefert das Diazoketon (I) mit Isothiocyanat (IV) das Acenaphthenoisoxazolinthion (V), dessen katalytische Hydrierung unter Ringspaltung zu dem Thiocarbamoylderivat (VI) verläuft.
Additive manufacturing of polypropylene micro and nano composites through fused filament fabrication for automotive repair applications (2022)

Abstract The emerging Additive manufacturing technologies are being adopted by different industries, which require developing new materials and procedures. Here we report the development of polypropylene (PP) based composite materials for fused filament fabrication (FFF) process with the aim of enabling fully automatic robotic repair application of plastic components in automotive industry. A key challenge in repair and joining of polyolefins, which are widely used in such applications, is understanding the interplay of microstructural features and the joining mechanisms employed to achieve a uniform and fully functional repaired components. Specifically, for components manufactured from polypropylene based material, we show that the addition of ethylene propylene diene monomer (EPDM), polyisobutylene (PIB) and carbon black (CB) successfully modifies its matrix and produces a composite material ideal for additively repairing of complex geometries found in the automotive applications. This was brought about by effective reduction of the crystallinity of the composite PP matrix from 46.2% to 34.4% and resulting in a net reduction in warpage of the FFF 3D printed samples. Further, the thermal stability of the developed composite was improved with the addition of a moderate amount of carbon filler, enabling an FFF process with higher hot‐end temperatures, which subsequently allowed for tuning of the raw material's viscosity, and hence ensuring consistent deposition of molten filaments for building successive layers. Mechanical properties' analysis revealed that the addition of 10 wt.% CB increased the true stiffness (storage modulus) by 20%, the impact strength by 62%, with the drop in ultimate tensile strength of 11%. The optimal elongation at break and toughness were achieved for the samples containing 2 wt.% CB increasing these key properties by 62% and 58%, respectively. In terms of the melt flow index (MFI), as a key rheological indicator, the measured value ranged between 12.5 and 19.0 for all compositions suitable for the FFF process. Morphological analysis of the extruded filaments and fracture surface of impact test samples showed a mesoscale interspersion of polymer phases and a proper filler dispersion in the matrix material with sizes ranging from hundreds of nanometers to hundreds of microns. The developed 3D‐printable PP composite filament was successfully used in a robotic cell to repair broken plastic lugs of a car headlight assembly.
Synthesis and Photovoltaic Properties of Low Band Gap π-conjugated Polymers Based on 2-pyran-4-ylidene-malononitrile Derivatives (2009)

A series of poly[2-(2,6-dimethylpyran-4-ylidene)malononitrile-alt-1,4-bis(dodecyloxy)-2,5-divinylbenzene] (PM-PPV), poly[2-{2,6-Bis-[2-(5-bromothiophen-2-yl)-vinyl]-pyran-4-ylidene}-malononitrile-alt-1,4-bis(dodecyloxy)-2,5-divinylbenzene] (PMT-PPV) and poly[2-[2,6-Bis-(2-{4-[(4-bromophenyl)-phenylamino]-phenyl}-vinyl)-pyran-4-ylidene]-malononitrile-alt-1,4-bis(dodecyloxy)-2,5-divinylbenzene] (PMTPA-PPV) were synthesized by the Heck coupling reaction. The band gap of PM-PPV, PMT-PPV and PMTPA-PPV were 2.18 eV, 1.90 eV and 2.07 eV, respectively. The LUMO energy levels of PM-PPV, PMT-PPV and PMTPA-PPV were 3.65 eV, 3.54 eV and 3.62 eV, respectively and the HOMO energy levels of those were 5.83 eV, 5.61eV and 5.52 eV, respectively. The photovoltaic devices based on the polymers was fabricated. The efficiency of the solar cells based on PM-PPV, PMT-PPV and PMTPA-PPV were 0.028%, 0.031% and 0.11%, respectively and the open circuit voltage (Voc) was 0.59 V∼0.69 V under AM 1.5 G and 1 sun condition (100 mA/).
Bone marrow mesenchymal stromal cells (BM-MSCs) from healthy donors and auto-immune disease patients reduce the proliferation of autologous- and allogeneic-stimulated lymphocytes in vitro (2006)

The BM-MSCs exhibit extensive anti-proliferative properties against lymphocytes under different conditions. This property might offer a form of immunomodulatory cellular therapy for AD patients if further confirmed in animal models.
Multiobjective genetic algorithm solution to the optimum economic and environmental performance problem of small autonomous hybrid power systems with renewables (2010)

The overall evaluation of small autonomous hybrid power systems (SAHPS) that contain renewable and conventional power sources depends on economic and environmental criteria, which are often conflicting objectives. The solution of this problem belongs to the field of non-linear combinatorial multiobjective optimisation. In a multiobjective optimisation problem, the target is not to find an optimal solution, but a set of non-dominated solutions called Pareto-set. The present article considers as an economic objective the minimisation of system&apos;s cost of energy (COE), whereas the environmental objective is the minimisation of the total greenhouse gas (GHG) emissions of the system during its lifetime. The main novelty of this article is that the calculation of GHG emissions is based on life cycle analysis (LCA) of each system&apos;s component. In LCA, the whole life cycle emissions of a component are taken into account, from raw materials extraction to final disposal/recycling. This article adopts the non-dominated sorting genetic algorithm (NSGA-II), which in combination with a proposed local search procedure effectively solves the multiobjective optimisation problem of SAHPS. Two main categories of SAHPS are examined with different energy storage: lead-acid batteries and hydrogen storage. The results indicate the superiority of batteries under both economic and environmental criteria.