gebhart/patrepeval huggingface dataset:
Analytical method for starting performance calculation of induction motors considering skin effect and leakage flux saturation (2014)

Due to skin effect and of the leakage flux saturation, the stator and rotor leakage impedance parameters of cage induction motors are variable in start process, which may cause the changes in electromotive force and affect the calculation accuracy of starting performance. In order to accurately calculate the induction motor starting performance with the above factors considered, this paper establishes a new analytical model, in which the dynamic variation of the parameters, such as stator leakage, rotor leakage and rotor resistance can be considered effectively. Then, taking YKK710-4 3150kW motor as an example, the starting current, starting torque and speed performance are contrastive analyzed. The results show that the leakage reactance is smaller and the starting current increase and starting response is faster.
Weyl metallic state induced by helical magnetic order (2023)

In the rapidly expanding field of topological materials there is growing interest in systems whose topological electronic band features can be induced or controlled by magnetism. Magnetic Weyl semimetals, which contain linear band crossings near the Fermi level, are of particular interest owing to their exotic charge and spin transport properties. Up to now, the majority of magnetic Weyl semimetals have been realized in ferro- or ferrimagnetically ordered compounds, but a disadvantage of these materials for practical use is their stray magnetic field which limits the minimum size of devices. Here we show that Weyl nodes can be induced by a helical spin configuration, in which the magnetization is fully compensated. Using a combination of neutron diffraction and resonant elastic x-ray scattering, we find that EuCuAs develops a planar helical structure below $T_\textrm{N}$ = 14.5 K which induces Weyl nodes along the $Γ$--A high symmetry line in the Brillouin zone.
West Nile Virus Chorioretinitis in the Presence of Negative Cerebrospinal Fluid Polymerase Chain Reaction Results (2021)

This report highlights 3 unique cases of WNV chorioretinitis in which NAAT of cerebrospinal fluid failed to identify WNV as the inciting agent. These cases stress the importance of serum serologic testing in diagnosing WNV infection.
<title>Impedance tomography using internal current density distribution measured by nuclear magnetic resonance</title> (1994)

We have proposed a new method of image reconstruction in EIT (electrical impedance tomography). In EIT, we usually use boundary current and voltage measurements to provide the information about the spatial distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. The new method uses internal current density data measured by NMR imaging technique. By knowing the internal current density, we can improve the accuracy of the impedance images.
KDM6B promotes activation of the oncogenic CDK4/6-pRB-E2F pathway by maintaining enhancer activity in MYCN-amplified neuroblastoma (2020)

ABSTRACT The H3K27me2/me3 histone demethylase KDM6B is over-expressed in neuroblastoma and is essential to neuroblastoma cell survival. While the KDM6B inhibitor, GSK-J4, has shown activity in in vitro and in vivo preclinical models, the mechanism of action remains poorly defined. We demonstrate that genetic and pharmacologic inhibition of KDM6B downregulates the pRB-E2F transcriptome and MYCN expression. Chemical genetic analyses show that high expression of the E2F transcriptome is positively correlated with sensitivity of cancer cells to GSK-J4. Mechanistically, inhibition of KDM6B activity 1) reduces the chromatin accessibility of E2F target genes and MYCN, 2) selectively leads to an increase of H3K27me3 but a decrease of the enhancer mark H3K4me1 at the CTCF and BORIS binding sites, which may, consequently, disrupt the long-range chromatin interaction of MYCN and E2F target genes, and 3) phenocopies the transcriptome induced by the specific CDK4/6 inhibitor palbociclib. Overexpression of CDK4/6 or Rb1 knockout confers neuroblastoma cell resistance to both palbociclib and GSK-J4. A gene signature targeted by KDM6B inhibition is associated with poor survival of patients with neuroblastoma regardless of the MYCN status. These data indicate that KDM6B activity promotes an oncogenic CDK4/6-pRB-E2F pathway in neuroblastoma cells via H3K27me3-dependent enhancer-promoter interactions, providing a rationale to target KDM6B for high-risk neuroblastoma.
Hybrid Dendritic Molecules with Confined Chromophore Architecture to Tune Fluorescence Efficiency (2008)

The aim of this publication is to present a general strategy to engineer more efficient photoluminescent dendritic molecules based on polyhedral oligomeric silsesquioxane (POSS) cores. A series of chromophores were grafted on POSS cores to form dendritic molecules for which steric hindrance was used as a trigger to tune their photophysical properties. For fluorescence in the blue/near-UV spectral ranges, 4-vinylbiphenyl molecules were chosen as model chromophores to present a general approach based on stable chemistry and bulky groups grafted to the chromophores to enhance photoluminescence efficiency of the dendritic molecules. Photoluminescence quantum yields as well as steady-state and time-resolved solution spectroscopy along with molecular dynamics investigation and electronic structure calculations on a family of new materials are reported. We highlight an apparent contrast between free chromophore and dendritic molecules photophysical properties and show that chromophores' engineering and confinement around an inorganic core allows the design of more efficient photoluminescent dendritic molecules relevant to sensors and hybrid light-emitting diodes.
Spatial trapping of short pulses in Ti:PPLN waveguides (2002)

International audience
Complex magmatic-tectonic interactions during the 2020 Makushin Volcano, Alaska, earthquake swarm (2021)

&amp;lt;p&amp;gt;We investigate the processes driving&amp;lt;strong&amp;gt; &amp;lt;/strong&amp;gt;a significant earthquake swarm that occurred between June and December 2020 on Unalaska Island, Alaska, ~12 km southeast of the summit of Makushin Volcano. The swarm was energetic, with two M&amp;gt;4 events that were widely felt by the population in Dutch Harbor, ~ 15 km west of the epicenters. This is the strongest seismic activity ever recorded at Makushin since instrumental monitoring began in 1996. To date, no eruptive activity or other surface changes have been observed at the volcano in satellite views, webcam images, GPS or InSAR. Seismic swarms close to volcanoes are often associated with the onset of unrest that can lead to eruption. However, determining whether they reflect magmatic rather than tectonic stresses is challenging. Here, we integrate information from space-time patterns of the hypocenters of the swarm earthquakes with their double-couple fault-plane solutions (FPS). We relocate swarm events using double-difference relocation techniques and a 3D velocity model. We find that most of the events cluster into two perpendicular lineaments with NW-SE and SW-NE orientations, but no apparent migration in time towards a preferred fault. On the one hand, the lack of temporal migration (with both faults slipping concurrently), and FPS for M3+ events consistent with regional stresses, seem to indicate a tectonic driving process. On the other hand, FPS for the lower-magnitude earthquakes have 90&amp;amp;#176;-rotated P-axes perpendicular to the regional principal stress orientation, providing strong evidence for dike inflation/magma intrusion. Coulomb stress modeling indicates that the rotated FPS are best explained by an inflating dike to the SW of the swarm epicenters, in a zone of long-term elevated seismicity. This complex overlapping of regional and magmatic stresses is also evident in the statistical analysis of the sequence, which started as a main-shock/aftershock sequence with the first event having the largest magnitude, and evolved into a swarm sequence indicative of a more pronounced role of magmatic processes.&amp;lt;/p&amp;gt;
Synthèse et Evaluation de nouveau agents de protection contre les rayonnements ionisants (2009)

Ce travail de thèse est consacré à la synthèse de nouveaux dérivés d'acides pulviniques et à l'évaluation de leurs propriétés antioxydante et radioprotectrice. Cette étude a été réalisée dans le but de développer de nouveaux agents de protection contre les rayonnements ionisants. Une nouvelle voie d'accès à des dérivés d'acides pulviniques a été mise au point en partant du L-tartrate de diméthyle. Elle est basée notamment sur une étape de cyclisation de Dieckmann, une déshydratation et un couplage de Suzuki-Miyaura. Elle permet une préparation efficace et concise de différents dérivés d'acides pulviniques : des dérivés tétroniques comportant un a-hydroxyester, des dérivés pulviniques monosubstitués et des pulvinates de méthyle. Une modification de cette méthode a été réalisée afin de préparer des pulvinones. Cette stratégie conduit en quatre étapes aux pulvinones souhaitées. La rapidité de cette méthode est apportée par un processus tandem, réalisé en dernière étape, mettant en jeu une cyclisation de Dieckmann et une b-élimination. Une synthèse d'acides 3-aryltétramiques a également été mise au point afin de préparer des dérivés azotés d'acides pulviniques. L'activité antioxydante des composés préparés a ensuite été évaluée à l'aide de différents tests : DPPH, ABTS, protection de la thymidine et de l'ADN et étude de la peroxydation lipidique. Ces évaluations ont permis de définir des relations structure-activité intéressantes des dérivés pulviniques. Elles ont montré que plusieurs dérivés possédaient de très bonnes actvités antioxydantes. Enfin, des tests de radioprotection sur des cellules TK6 et des souris ont pu être réalisés sur une sélection de composés.
Normalisation of hedonism? Challenging convergence culture through ethnographic studies of alcohol consumption by young adults – a feminist exploration (2015)

Three Normalisation of hedonism? Challenging convergence culture through ethnographic studies of alcohol consumption by young adults – a feminist exploration was published in Women and Alcohol on page 45.
Wheat Bran Oil and Its Fractions Inhibit Human Colon Cancer Cell Growth and Intestinal Tumorigenesis in Apcmin/+ Mice (2006)

This study was designed to investigate the cancer preventive activities of wheat bran (WB) oil. We studied the colon cancer preventive effects of WB oil and its subfractions in the Apc(min/+) mouse model, a recognized mouse model for human colorectal cancer, and used human colon cancer cell lines (HCT-116 and HT-29) to identify possible active fractions in WB oil. Our results showed that the oil fraction of WB was more active than the water fraction against the growth of human colon cancer cell lines and that 2% WB oil significantly inhibited the overall tumorigenesis by 35.7% (p < 0.0001) in the Apc(min/+) mouse model. The WB oil was further fractioned into nonpolar lipids and phytochemicals and the phytochemical fraction was fractionated into phytosterols and phytosterol ferulates, 5-alk(en)ylresorcinols, and unidentified constituents by normal phase silica gel column chromatography. Results on cell culture showed that the phytochemical fraction had a higher inhibitory effect on HCT-116 human colon cancer cells than that of WB oil, whereas the nonpolar lipid fraction had less growth inhibitory effectiveness. However, neither fractions showed a stronger inhibition than WB oil in the Apc(min/+) mouse model. The current results demonstrate, for the first time, the intestinal cancer preventive activity of WB oil. The active ingredients, however, remain to be identified.
Electron-spin-resonance Spectroscopy of Radiation-induced Free Radicals in Irradiated Single Crystals of Thymine Monohydrate (1970)

SummaryThe molecular structures of free radicals formed in irradiated single crystals of thymine monohydrate were investigated by ESR spectroscopy. Two different types of radicals were observed, their relative contribution in the spectra depending on the experimental conditions. One is the previously known 5,6-dihydro-5-thymyl radical, the conformation of which is discussed briefly. It is proposed that the additional radical is formed by loss of a hydrogen atom from the methyl group, leaving an unpaired electron in a 2pz orbital of the methyl carbon atom. The hyperfine spectrum of this radical originates from the interaction of the unpaired electron with the two remaining α-protons of the methyl group and, via resonance delocalization, with the α-proton attached to carbon atom C6 of the thymine molecule. The hyperfine tensors of these couplings are given together with the g-tensor of this radical.
Recent advances of ultra-broadband fiberoptics wavelength converters (2002)

Advantages of the use of short high-nonlinearity dispersion-shifted fibers (HNL-DSFs) to generate broadband four-wave mixing (FWM) for wavelength conversion were discussed. Making use of an optimized amount of modulational instability (MI) with high power pump, we achieved 15.3 nm enhancement of the conversion bandwidth and 22.5 dB enhancement of the conversion efficiency.
Total cell‑free DNA measurement in metastatic colorectal cancer with a fast and easy direct fluorescent assay (2022)

Treatment for metastatic colorectal cancer (mCRC) is focused on prolonging survival and maintaining quality of life. It is important to establish prognostic and predictive markers to avoid extended, ineffective treatment. The aim of the present study was, by a novel approach, to analyze the association between cell-free (cf)DNA levels and outcome in patients receiving systemic therapy for incurable mCRC. The study was a prospective non-interventional biomarker study for patients receiving standard of systemic treatment for mCRC. Patients with mCRC, who, according to standard guidelines, were considered for treatment with EGFR inhibitors, were included. The cfDNA levels in consecutive plasma samples were measured by a direct fluorescence assay. The study included 47 patients. Blood samples were available at baseline (n=47); prior to the third treatment cycle (n=31); the first (n=33), second (n=22) and third response evaluation during treatment (n=17); and at progression (n=22). The disease control rate was 42 and 91% in patients with high (≥75<sup>th</sup> percentile of baseline cfDNA levels) and low cfDNA levels (<75<sup>th</sup> percentile of baseline cfDNA levels), respectively (P<0.001). Median progression-free survival (PFS) was 3.8 and 8.5 months in patients with high and low cfDNA levels, respectively (hazard ratio=3.03, 95% CI 1.46-6.29, P<0.01). Median overall survival (OS) was 5.0 and 26.6 months in patients with high and low cfDNA levels, respectively (hazard ratio=3.48, 95% CI 1.44-8.44, P<0.01). In the multivariate analysis, baseline cfDNA levels remained a significant predictor of PFS and OS. In conclusion, cfDNA is a promising prognostic tool in the personalized treatment of mCRC. cfDNA levels were estimated by a simple, rapid and inexpensive method (OPTIPAL II: ClinicalTrials.gov identifier no. NCT03750175; registered November 21, 2018).
Three-dimensional postoperative accuracy of extra-articular forearm osteotomies using CT-scan based patient-specific surgical guides (2015)

The technique demonstrated high accuracy in performing closing wedge (or single-cut) osteotomies. However, for opening wedge osteotomies with extensive lengthening, probably due to the fact that precise reduction was difficult to achieve or maintain, the final corrections were less accurate.
Localization of small molecules in plant tissues visualized by an imaging mass spectrometer (2016)

質量顕微鏡では，レーザーを用いてサンプル組織の一部をイオン化し，イオン化した物質を質量分析器に取り込んで質量電荷比を測定する分析を，レーザー照射部位を二次元スキャンしながら行うことによって，サンプル組織の物質分布を推定することができる．高空間分解能（<10 μm）を持つMALDI/LDIイオン源を市販の9.4 T（テスラ）-FTICR/MSにつなぐことで，超高質量分解能（>100,000）と超高質量精度（<1 ppm）を併せ持つ質量顕微鏡を開発し，植物サンプルをスキャンし，代謝物質の組織分布を明らかにすることを試みた．シロイヌナズナの根組織を用い，質量顕微鏡による代謝産物の網羅的解析を進めたところ，根全体，根端，伸長域などで，固有の質量を持つ物質が異なった分布をすることが見出された．また，ニチニチソウを用いて二次代謝産物がどのように分布するかについての解析も行った．ニチニチソウの葉や茎の組織では，葉肉細胞，表皮細胞，異形細胞といった複数の細胞間を代謝産物が移動することで，二次代謝産物（テルペノイドインドールアルカロイド）の合成が進められることが報告されているが，質量顕微鏡を使用することで茎における二次代謝産物の細胞間分布の違いを直接的に見出すことに成功した．
A parallel square-root algorithm for modified extended Kalman filter (1992)

A parallel square-root algorithm and its systolic array implementation are proposed for performing modified extended Kalman filtering (MEKF). The proposed parallel square-root algorithm is designed based on the singular value decomposition (SVD) and the Faddeev algorithm, and a very large scale integration (VLSI) systolic array architecture is developed for its implementation. Compared to other square root Kalman filtering algorithms, the proposed method is more numerically stable. The VLSI architecture described has good parallel and pipelining characteristics in applying to the MEKF and achieves higher efficiency. For n-dimensional state vector estimations, the proposed architecture consists of O(2n/sup 2/) processing elements and uses O((s+17)n) time-steps for a complete iteration at each instant, in contrast to the complexity of O((s+6)n/sup 3/) time-steps for a sequential implementation, where s approximately=log n.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Zinc‐Finger Proteins for Site‐Specific Protein Positioning on DNA‐Origami Structures (2012)

Fingerzeig: Zinkfingerproteine sind Adaptoren, die Positionen in DNA-Origami-Strukturen ortsselektiv ansteuern. Zwei solche Adaptoren können spezifische Positionen in orthogonaler Weise ansteuern, was in Escherichia-coli-Lysat, das Fusionsproteine der Adaptoren enthielt, zum Aufbau der erwarteten Protein-DNA-Struktur angewendet wurde. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Human Action Recognition from Various Data Modalities: A Review (2021)

This is a survey on human action recognition from various data modalities.
Supplemental Figure 5A from Exposure–Response Analysis of Alvocidib (Flavopiridol) Treatment by Bolus or Hybrid Administration in Newly Diagnosed or Relapsed/Refractory Acute Leukemia Patients (2023)

&lt;p&gt;Representative Individual Concentration versus Time Pharmacokinetic Profiles for Total or Unbound lavopiridol Using Bolus (A) or Hybrid (B) Dosing Schemes.&lt;/p&gt;
MPI versus MPI+OpenMP on the IBM SP for the NAS Benchmarks (2000)

The hybrid memory model of clusters of multiprocessors raises two issues: programming model and performance. Many parallel programs have been written by using the MPI standard. To evaluate the pertinence of hybrid models for existing MPI codes, we compare a unified model (MPI) and a hybrid one (OpenMP fine grain parallelization after profiling) for the NAS 2.3 benchmarks on two IBM SP systems. The superiority of one model depends on 1) the level of shared memory model parallelization, 2) the communication patterns and 3) the memory access patterns. The relative speeds of the main architecture components (CPU, memory, and network) are of tremendous importance for selecting one model. With the used hybrid model, our results show that a unified MPI approach is better for most of the benchmarks. The hybrid approach becomes better only when fast processors make the communication performance significant and the level of parallelization is sufficient.
Benzotriazole-Assisted Synthesis ofN-(α-Cyanoalkyl)sulfonamides (1997)

Abstract N-(α-Benzotriazol-1-ylalkyl)sulfonamides, readily available from benzotriazole, an aldehyde and a sulfonamide, are converted into the corresponding N-(α-cyanoalkyl)sulfonamides in good yields by treatment with potassium cyanide.
지방산분석을 이용한 Pseudomonas aeruginosa의 동정 (2005)

Cellular fatty acid composition of 17 strains of the Pseudomonas aeruginosa was determined by gas-liquid chromatography isolated from environmental and clinical sample in a C university hospital. Straight-chain saturated acid of C16:0 and straight-chain unsaturated acid of C18:1 with a double bond were commonly found in all the strains tested. The presence of 12:0 3OH (3-10%), 16:0 (18-28%), and 18:1w7c (17-37%) showed the characteristics of the species in the Pseudomonas. Bacterial fatty acid composition was considered to be useful for the study of interrelation and for rapid identification of the bacteria.
17.5: Fabrication of CdSe/ZnS Quantum Dot Color Filters via Photolithography Process (2018)

Quantum dots color filter (QDCF) is potential to be a game‐changer for display and micro LED industry. In this paper, highly fluorescent QDCF have been prepared by changing surface active ligand of CdSe@ZnS to nonreactive ligand for photolithographic patterning. The quantum dots (QDs) with inactivated ligand avoids chemical reaction during the photolithography process. The 4 μm thickness QDCF with 28.8% (red) absolute PL quantum yield (λ max of 630.16 nm) has been achieved after the photolithograpy process, while the QDs with surface active sites failed to form a patterned film. This may be due to the coordination of activated bonds with photoresist and the occurrence of complexation reaction.
Computer-derived nuclear features compared with axillary lymph node status for breast carcinoma prognosis (1997)

Computer analysis of a preoperative FNA more accurately identified prognostically favorable patients than did pathologic examination of axillary lymph nodes and may obviate the need for routine axillary lymph node dissection.
Inhibition of glycogen synthase kinase-3 activity triggers an apoptotic response in pancreatic cancer cells through JNK-dependent mechanisms (2011)

Recent evidences suggest that the activity of glycogen synthase kinase-3 (GSK3) contributes to the tumorigenic potential of pancreatic cancer cells through modulation of cell proliferation and survival. However, further investigations are needed to identify GSK3-dependent mechanisms involved in the control of pancreatic cancer cell proliferation and survival. This study was undertaken to provide further support for a role of GSK3 in pancreatic cancer cell growth as well as to identify new cellular and molecular mechanisms involved. Herein, we demonstrate that prolonged inhibition of GSK3 triggers an apoptotic response only in human pancreatic cancer cells but not in human non-transformed pancreatic epithelial cells. We show that prolonged inhibition of GSK3 activity increases Bim messenger RNA and protein expressions. Moreover, we provide evidence that activation of the c-jun N-terminal kinase (JNK) pathway is necessary for the GSK3 inhibition-mediated increase in Bim expression and apoptotic response. Finally, we demonstrate that concomitant inhibition of GSK3 potentiates the death ligand-induced apoptotic response in pancreatic cancer cells but not in non-transformed pancreatic epithelial cells and that this effect also requires JNK activity. Considering that different approaches leading to stimulation of death receptor signaling are under clinical trials for treatment of unresectable or metastatic pancreatic cancer, inhibition of GSK3 could represent an attractive new avenue to improve their effectiveness.