gebhart/patrepeval huggingface dataset:
Indoor GPS-denied Context Based SLAM Aided Guidance for Autonomous Unmanned Aerial Systems (2013)

Autonomous exploration and mapping of environments is an important problem in robotics. Efficient exploration of structured environments requires that the robot utilize region-specific exploration strategies and coordinate with search other agents. This paper details the exploration and guidance system of a multi-quadrotor unmanned aerial system (UAS) capable of exploring cluttered indoor areas without relying on any external aides. Specifically, a graph-based frontier search algorithm which is aided by an onboard Simultaneous Localization and Mapping (SLAM) system is developed and flight tested. A technique is developed in for segmenting an indoor office-like environment into regions and to utilize the SLAM map to conduct specific activities in these regions. A goal-directed exploration strategy is created building on existing hybrid deliberative-reactive approaches to exploration. An obstacle avoidance and guidance system is implemented to ensure that the vehicle explores maximum indoor area while avoiding obstacles. The environment is explored and regions are segmented by detecting rooms and hallways which expedites the search. The multi-vehicle system is Georgia Tech Aerial Robotic Team's entry for the annual International Aerial Robotics Competition (IARC).
Repeated Acute Exacerbations of Chronic Inflammatory Demyelinating Polyradiculoneuropathy Accompanied by Pain and Swelling in Distal Extremities (2023)

An 81-year-old man experienced acute progression of weakness in the extremities accompanied by a fever, tenderness, and swelling in distal parts of the extremities. He had flaccid tetraparesis with fasciculations and general hyporeflexia. Nerve conduction studies indicated demyelinating sensorimotor neuropathy. A cerebrospinal fluid examination revealed elevated proteins without pleocytosis. Immunological treatments were effective, but his symptoms exhibited repeated relapse and remission phases. He was diagnosed with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) with an acute onset. The highlight of this case is pain with inflammatory reaction recognized as red flags of CIDP, with the clinical course and electrophysiological findings compatible with CIDP.
Relationship Between Insulin Sensitivity and Sphingomyelin Signaling Pathway in Human Skeletal Muscle (2004)

In vitro studies revealed that insulin resistance might be associated with the intracellular formation of ceramide, the second messenger in the sphingomyelin signaling pathway. The aim of the present study was to examine the content and composition of fatty acids in ceramide and sphingomyelin in human muscle and to evaluate their relationships with insulin sensitivity. The study was conducted on 27 male subjects with normal glucose tolerance. Euglycemic-hyperinsulinemic clamps and biopsies of vastus lateralis muscle were performed. In 10 subjects, additional biopsies were taken after a 4-h clamp and after a clamp with concurrent Intralipid/heparin infusion. We identified 13 ceramides and sphingomyelins according to fatty acid residues. Insulin sensitivity was related to total ceramide content (r = -0.49, P = 0.01) and to ceramide consisting of palmitic (r = -0.48, P = 0.011), palmitoleic (r = -0.45, P = 0.019), mirystic (r = -0.42, P = 0.028), and nervonic acid (r = -0.39, P = 0.047). Hyperinsulinemia did not affect estimated muscle parameters. Intralipid/heparin infusion resulted in a 24.73% decrease in insulin sensitivity (P = 0.007) and a 47.81% increase in ceramide content (P = 0.005). These changes were significantly related to each other (r = -0.64, P = 0.046). A relationship with the decrease in insulin sensitivity was also observed for ceramides consisting of palmitic (r = -0.68, P = 0.03) and linoleic (r = -0.66, P = 0.038) acid. Our data indicate that the sphingomyelin signaling pathway in muscle might be an important factor determining the development of insulin resistance in humans.
Hydrogel membranes with mesh size asymmetry based on the gradient crosslinking of poly(vinyl alcohol) (1999)

Poly(vinyl alcohol) (PVA) hydrogel membranes with mesh size asymmetry were prepared and their transport properties were studied. Homogeneous membranes with water contents of 82%, 76% and 72% were prepared by crosslinking PVA with glutaraldehyde. These membranes were then modified to create asymmetry by establishing a glutaraldehyde concentration gradient across the hydrogel thickness. The reaction time and magnitude of the glutaraldehyde concentration gradient were varied to determine the optimum values of permeability and selectivity. Permeation experiments with creatinine, Fab and IgG were performed in a stirred diffusion cell through homogeneous and asymmetric PVA hydrogels. A modified version of the multiple-membrane technique was used to determine boundary layer resistance in order to determine the intrinsic membrane permeability. As expected, the selectivity of creatinine over IgG increased as the modification time increased. However, the selectivity of Fab over IgG initially increased as the modification time increased, but then decreased at longer times, indicating that the increased crosslinking at the surface effectively blocks both proteins. At a given value of IgG rejection, the asymmetric membranes had higher creatinine and Fab permeabilities than the corresponding homogeneous membranes. This indicates that creating mesh size asymmetry in a hydrogel can result in a high-flux, high-selectivity membrane for cell encapsulation or bioseparations.
Toward Data-domain Waveform Inversion of Reflected Waves (2013)

Full Waveform Inversion is becoming a powerful tool for quantitative seismic imaging from wide-azimuth seismic data. The method is today mainly used as a high-resolution tomography in the Earth zones sampled by both reflected and diving events. The classical formulation however prevents the reconstruction of the low-part of the wavenumber spectrum of the velocity model, from reflection-only data. The used of reflections in waveform inversion is a crucial challenge for deep imaging. This study, through a simple canonical example, first analyses the issue of classical waveform inversion formalism when used with reflection data. It is then shown that if a prior knowledge of reflectivity can be known, reflected waves can be be exploited in a data-domain approach to retrieve the long wavelength of the velocity, in particular when we used appropriate misfit measurement as the cross-correlation that overcome cycle-skipping issues, and inversion domain as the pseudo-depth domain that preserves the invariant property of zero-offset time.
Reconfigurable Spintronics Wheatstone Bridge Sensors With Offset Voltage Compensation at Wafer Level (2019)

Industrial requirements are continuously pushing the sensor limits toward higher signal-to-noise ratio under harsh environments, without compromising production costs by additional electronics. Non-full resistive Wheatstone bridge architectures arise as a compact and cheaper alternative to full-bridge measurement schemes, despite a lower output, linearity, and immunity to thermal drifts promoted by the replacement of the out-of-phase sensing elements by passive elements. However, the combination of state-of-the-art magnetoresistive (MR) sensors with thermally compatible materials used as tunable thin-film resistor at wafer level can lead to competitive prototypes for applications with high constraints. Therefore, the resistivity and the temperature coefficient of resistance (TCR) of Cr, Ti, and TiW thin films were evaluated as potential candidates for a thermal and electrical stable non-full MR bridge. Within a TCR around 1059 ± 12 ppm/°C for a spin-valve sensor lying between the values observed for a Ti thickness range of 300 Å up to 500 Å (571.9 ± 8.3 and 1347 ± 69 ppm/°C, respectively), a sin/cos magnetic encoder was prototyped in a non-full-bridge architecture with a thermal offset drift of 51.48 ± 0.25 nV/Vcc/°C and an offset voltage of 16 mV/Vcc.
Extreme Elevation of Transaminase Levels in Acute Heart Disease—a Problem in Differential Diagnosis? (1976)

Five patients admitted to the Coronary Care Unit at the Department of Medicine, Serafimerlasarettet, who developed extreme elevation of transaminase levels, are discussed in terms of problems in differential diagnosis. All five had manifest right ventricular failure on admission and four also had hypotension. Three of the patients died, two survived. The three post-mortem examinations showed extensive infarctions of the left ventricle and septum. The two survivors had had a prolonged ventricular tachycardia and a probable silent infarct, respectively. It is concluded that the extremely high transaminase levels sometimes seen in acute cardiac disease are predominantly due to sizeable amounts released by the liver as a result of central necrosis of the liver cells. The probable prerequisite for the development of central necrosis of the liver in acute cardiac disease is usually the combination of right ventricular failure and hypotension, which in turn are most often due to extensive left ventricular infarcts.
Measurement of thermal diffusivities through processing of infrared images (1995)

The measurement of the thermal diffusivity of a thin layer in the direction of its plane is usually a difficult operation. The standard ‘‘flash technique’’ is very appropriate for diffusivity measurement in the direction of the thickness of the sample but adaptations of this method to in-plane measurements remain very sensitive to the position and form of heat excitation and temperature sensors. The new procedure proposed here consists of applying any geometrically nonuniform heat impulse on the front face of the sample and recording the entire transient temperature image on the rear face thanks to an infrared camera. The influence of axial diffusion can be avoided for periods much longer than the axial diffusion characteristic time. Integral transforms on the radial space variables (Fourier transform) are very suitable for treating the temperature field and to estimate radial diffusivity. The main advantage of this method is to avoid any experimental precaution (no knowledge of the geometrical form of the excitation - replacement of the sensor positioning by an image calibration). Furthermore, the considerable number of data produced by the camera is processed using a statistical approach. The validation of the method is made on a homogeneous sample by comparison between the in-plane direction measurements (obtained with the present procedure) and the thickness direction measurements (obtained by the classical flash technique).
Variable voltage supply uses Zener dioxide as reference (1965)

Using a zener diode as the reference element, a simple transistorized circuit provides a stable variable reference voltage.
Tissue-Specific Profiling Reveals Transcriptome Alterations inArabidopsisMutants Lacking Morphological Phenotypes (2013)

Traditional genetic analysis relies on mutants with observable phenotypes. Mutants lacking visible abnormalities may nevertheless exhibit molecular differences useful for defining gene function. To examine this, we analyzed tissue-specific transcript profiles from Arabidopsis thaliana transcription factor gene mutants with known roles in root epidermis development, but lacking a single-gene mutant phenotype due to genetic redundancy. We discovered substantial transcriptional changes in each mutant, preferentially affecting root epidermal genes in a manner consistent with the known double mutant effects. Furthermore, comparing transcript profiles of single and double mutants, we observed remarkable variation in the sensitivity of target genes to the loss of one or both paralogous genes, including preferential effects on specific branches of the epidermal gene network, likely reflecting the pathways of paralog subfunctionalization during evolution. In addition, we analyzed the root epidermal transcriptome of the transparent testa glabra2 mutant to clarify its role in the network. These findings provide insight into the molecular basis of genetic redundancy and duplicate gene diversification at the level of a specific gene regulatory network, and they demonstrate the usefulness of tissue-specific transcript profiling to define gene function in mutants lacking informative visible changes in phenotype.
The Na+,K+/H+-antiporter Nha1 influences the plasma membrane potential ofSaccharomyces cerevisiae (2006)

There are three different sodium transport systems (Ena1-4p, Nha1p, Nhx1p) in Saccharomyces cerevisiae. The effect of their absence on the tolerance to alkali-metal cations and on the membrane potential was studied. All three sodium transporters were found to participate in the maintenance of Na+, Li+, K+ and Cs+ homeostasis. Measurements of the distribution of a fluorescent potentiometric probe (diS-C3(3) assay) in cell suspensions showed that the lack of all three transporters depolarizes the plasma membrane. The overexpression of the Na+,K+/H+ antiporter Nha1 resulted in the hyperpolarization of the plasma membrane and consequently increased the sensitivity to Cs+, Tl+ and hygromycin B. This is the first evidence that the activity of a Na+,K+/H+ antiporter could play a role in the homeostatic regulation of the plasma membrane potential in yeast cells.
Low Voltage/Low Power CORDIC based DHT chip implemented using Transmission Gate Logic on Sea of Gates (1998)

The objective of this study was to investigate the short- and long-term adverse effects of fibroblast growth factor-2 treatment of tympanic membrane perforations. A total of 134 patients with traumatic tympanic membrane perforations were randomly divided into two groups: an observational group and a fibroblast growth factor-2 treatment group. The closure rate, closure time and principal side-effects were compared between the groups at 6 and 12 months. At 6 months, 131 patients were examined to determine healing outcomes and short-term side-effects. The total closure rate differed significantly between the fibroblast growth factor-2 and observational groups (95.5% vs 73.4, p #x003C; 0.01). The fibroblast growth factor-treated group exhibited a significantly shorter closure time than the observational group (11.9±3.1 days vs 52.6 ± 18.1 days, p = 0.00). Three patients with secondary otitis media with effusion, and three with reperforations, were noted in the fibroblast growth factor-2 group. We additionally performed long-term follow-up on 89.1% of the patients in the observational group and 92.5% of the patients in the fibroblast growth factor-2 group; follow-up was performed 16-42 months after perforation closure. Only a small perforation of the pars flaccida developed in the fibroblast growth factor-2 group. No middle ear cholesteatoma was noted in either group. This study suggests that the topical application of fibroblast growth factor-2 to human traumatic tympanic membranes is safe. Otorrhoea was the most common short-term side-effect; other less common side-effects included otitis media with effusion and reperforation. No serious long-term side-effects were found.
Energy-Efficient Estimation of Correlated Data in Wireless Sensor Networks (2006)

In this paper, we study the energy-efficient distributed estimation problem for a wireless sensor network where a physical phenomena that produces correlated data is sensed by a set of spatially distributed sensor nodes and the resulting noisy observations are transmitted to a fusion center via noise-corrupted channels. We assume a Gaussian network model where (i) the data being sensed at different sensors are correlated and the correlation structure (in the form of a correlation matrix) is known at the fusion center, (ii) the links between the local sensors and the fusion center are subject to multipath fading plus AWGN, and the fading gains are available to the receiver node, and (iii) the central node uses the squared error distortion metric. We first determine the optimum power-distortion regions assuming (i) a multiple-letter, and (ii) a single-letter square distortion characterization. Next, for the two distortion characterization, we investigate the performance of an uncoded transmission approach where the noisy observations are only amplified-and-forwarded to the fusion center. At the fusion center, two different estimators are considered: (i) minimum mean-square error estimator (MMSE) that exploits the correlation, and (ii) best linear unbiased estimator (BLUE) that does not require or exploit the knowledge of the correlation matrix. For both estimators, we solve for the optimal power allocation that results in a minimum total transmission power while satisfying some distortion level for the estimate (for both multiple-letter and single-letter distortion metrics). The numerical comparisons between the two schemes indicate that the MMSE requires less power to attain the same distortion provided by the BLUE. Furthermore, comparisons between power-distortion region achieved by the theoretically optimum system and the uncoded system indicates that the performance gap between the two system becomes small for low level of correlation between the sensor observations. If observations at all sensor nodes are uncorrelated, the uncoded system attains the theoretically optimum system performance.
Bioaccumulation of mercury in pelagic fishes from the northern Gulf of Mexico (2007)

Total mercury (Hg) concentration was determined in the tissues of 10 pelagic fishes in the northern Gulf of Mexico, and dietary tracers (stable isotopes and fatty acids) were used to evaluate the relationship between Hg and feeding history. Highest Hg levels were observed in blue marlin (Makaira nigricans), carcharhinid sharks (Carcha rhinus spp.), and little tunny (Euthynnus alletteratus), ranging from 1.08 to 10.52 ppm. Moderate to low concentrations (&lt;1.0 ppm) were observed in blackfin tuna (Thunnus atlanticus), cobia (Rachycentron canadum), dolphinfish (Cory phaena hippurus), greater amberjack (Seriola dumerili), king mackerel (Scomberomorus cavalla), wahoo (Acantho cybium solandri), and yellowfin tuna (Thunnus albacares). For the majority of species examined, Hg concentrations did not vary significantly between location (Texas vs. Louisiana) or collection period (2002 and 2003). Significant positive relationships between Hg concentration and body size and (or) weight were detected for 6 of the 10 taxa examined. Hg concentration was also positively associated with trophic position. Three natural associations were identified using stable isotope and fatty acid signatures. Still, no connection between these natural trophic associations and Hg concentration was observed, suggesting that Hg concentration in pelagic fishes was more closely linked to trophic position and size than feeding history.
Enhancing Cross-Modal Retrieval Based on Modality-Specific and Embedding Spaces (2020)

A new approach that drastically improves cross-modal retrieval performance in vision and language (hereinafter referred to as “vision and language retrieval”) is proposed in this paper. Vision and language retrieval takes data of one modality as a query to retrieve relevant data of another modality, and it enables flexible retrieval across different modalities. Most of the existing methods learn optimal embeddings of visual and lingual information to a single common representation space. However, we argue that the forced embedding optimization results in loss of key information for sentences and images. In this paper, we propose an effective utilization of representation spaces in a simple but robust vision and language retrieval method. The proposed method makes use of multiple individual representation spaces through text-to-image and image-to-text models. Experimental results showed that the proposed approach enhances the performance of existing methods that embed visual and lingual information to a single common representation space.
ChemInform Abstract: Magnetic Ground State and Its Control in Porphyrin‐Based Magnets (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
NADPH biosensor-based identification of an alcohol dehydrogenase variant with improved catalytic properties caused by a single charge reversal at the protein surface (2020)

Alcohol dehydrogenases (ADHs) are used in reductive biotransformations for the production of valuable chiral alcohols. In this study, we used a high-throughput screening approach based on the NADPH biosensor pSenSox and fluorescence-activated cell sorting (FACS) to search for variants of the NADPH-dependent ADH of Lactobacillus brevis (LbADH) with improved activity for the reduction of 2,5-hexanedione to (2R,5R)-hexanediol. In a library of approx. 1.4 × 10<sup>6</sup> clones created by random mutagenesis we identified the variant LbADH<sup>K71E</sup>. Kinetic analysis of the purified enzyme revealed that LbADH<sup>K71E</sup> had a ~ 16% lowered K<sub>M</sub> value and a 17% higher V<sub>max</sub> for 2,5-hexanedione compared to the wild-type LbADH. Higher activities were also observed for the alternative substrates acetophenone, acetylpyridine, 2-hexanone, 4-hydroxy-2-butanone, and methyl acetoacetate. K71 is solvent-exposed on the surface of LbADH and not located within or close to the active site. Therefore, K71 is not an obvious target for rational protein engineering. The study demonstrates that high-throughput screening using the NADPH biosensor pSenSox represents a powerful method to find unexpected beneficial mutations in NADPH-dependent alcohol dehydrogenases that can be favorable in industrial biotransformations.
Supplementary Figure 4 from Inhibition of the Acetyltransferases p300 and CBP Reveals a Targetable Function for p300 in the Survival and Invasion Pathways of Prostate Cancer Cell Lines (2023)

Supplementary Figure 4 from Inhibition of the Acetyltransferases p300 and CBP Reveals a Targetable Function for p300 in the Survival and Invasion Pathways of Prostate Cancer Cell Lines
Chevron layer structures in surface stabilized ferroelectric liquid crystal (SSFLC) cells filled with a material which exhibits the chiral nematic to smectic C*phase transition (1991)

Abstract Single component liquid crystals which exhibit the chiral nematic (N*) to smectic C* (SC*) phase transition exhibit a large director tilt with respect to the local layer normal (typically 30 degrees or greater) in the SC* phase which appears immediately upon cooling through the N* - SC* transition. In the SSFLC geometry and in the presence of an applied AC field these materials have been observed to align with their molecular long axes oriented along the buffing direction (for a buffed polymer alignment treatment) and with two domains of the smectic layers symmetrically disposed at a large angle (approximately the director tilt angle) with respect to the buffing direction[1]. Furthermore, the layer domains are selectable with the application of a DC field applied normal to the bounding plates. We demonstrate, for the large tilt mixture SCE-10, that the layer domains in all cases adopt the chevron local layer structure[2] immediately upon cooling through the transition. With decreasing temperature in the SC* phase, the tilt of the layers with respect to the bounding plate normals (chevron tilt angle) is observed to monotonically increase as the interlayer spacing decreases. This lends further evidence that the mechanism for chevron formation is simply layer shrinkage.