gebhart/patrepeval huggingface dataset:
Diamagnetic Response of Exciton Complexes in Semiconductor Quantum Dots (2008)

We report measurements of diamagnetic shifts for different exciton complexes confined in small InAs quantum dots. The measured diamagnetic responses are sensitive to the number of carriers in the exciton complexes, with systematic differences between neutral excitons, biexcitons, and trions. Theoretical calculations suggest that such systematic differences arise from very different extents of electron and hole wave functions confined in small quantum dots. The measured magnetic response of Coulomb energies is found to vary with the cube of the wave function extent, and can be a sensitive probe to the electron-hole wave function asymmetry.
Biosynthesis of phycobilins. Ferredoxin-supported nadph-independent heme oxygenase and phycobilin-forming activities from Cyanidium caldarium. (1992)

The unicellular red alga, Cyanidium caldarium, synthesizes phycocyanobilin from protoheme via biliverdin IX alpha. In vitro transformation of protoheme to biliverdin IX alpha and biliverdin IX alpha to phycobilins were previously shown to require NADPH, ferredoxin, and ferredoxin-NADP+ reductase, as well as specific heme oxygenase and phycobilin formation enzymes. The role of NADPH in these reactions was investigated in this study. The C. caldarium enzymatic activities that catalyze biliverdin IX alpha formation from protoheme, and phycobilin formation from biliverdin IX alpha, were partially purified by differential (NH4)2SO4 precipitation. The enzyme fractions, when supplemented with a light-driven ferredoxin-reducing photosystem I fraction derived from spinach leaves, catalyzed light-dependent transformation of protoheme to biliverdin IX alpha and biliverdin IX alpha to phycobilins, with or without the addition of NADPH and ferredoxin-NADP+ reductase. In the dark, neither reaction occurred unless NADPH and ferredoxin-NADP+ reductase were supplied. These results indicate that the only role of NADPH in both reactions of phycobilin biosynthesis, in vitro, is to reduce ferredoxin via ferredoxin-NADP+ reductase and that reduced ferredoxin can directly supply the electrons needed to drive both steps in the transformation of protoheme to phycocyanobilin.
Water-assisted reconstruction on ferroelectric domain ends of triglycine sulfate (NH2CH2COOH)3·H2SO4 crystals (2000)

With a humidity-controlled AFM system, water-assisted reconstruction of triglycine sulfate (TGS) crystal surfaces has been investigated for two 180° ferroelectric domains. At high humidity, both holes and islands are found on the two different domain ends, owing to a strong dissolution of the TGS. The island growth on a negative domain end is accompanied by a simultaneous hole-enlargement. When humidity is lowered for a negative domain, the holes are filled up and the islands are increased and linked together at the same time. After a longer reconstruction time at the same low humidity, the islands on the negative domain reduce their sizes, owing to water-assisted molecular relocations. For a positive domain at high humidity, tiny holes can be formed inside an island. However, the hole-number in a positive domain decreases significantly when humidity is reduced. The driving force for surface reconstruction can be associated with the molecular and crystal structures, surface mass transport, and minimization of total energy. Based on the surface topographies investigated at low humidity, the domain polarity of the TGS crystal can be assigned unambiguously.
pCRM1exportome: database of predicted CRM1-dependent Nuclear Export Signal (NES) motifs in cancer-related genes (2019)

Supplementary data are available at Bioinformatics online.
Agrobacterium transcriptional regulator Ros is a prokaryotic zinc finger protein that regulates the plant oncogene ipt (1998)

Virulence genes of Agrobacterium tumefaciens are under the control of positive and negative transcriptional regulators. We found that the transcriptional regulator Ros controls expression of the plant oncogene ipt, which encodes isopentenyl transferase, in A. tumefaciens. This enzyme is involved in biosynthesis of the plant growth hormone cytokinin in the host plant. An ipt promoter::cat reporter gene fusion showed a 10-fold increase in ipt promoter activity in A. tumefaciens ros mutant strains when compared with wild type. Also, increased levels (10- to 20-fold) of isopentenyl adenosine, the product of the reaction catalyzed by isopentenyl transferase, were detected in ros mutant strains. In vitro studies using purified Ros showed it binds directly to the ipt promoter. Analysis of the deduced Ros amino acid sequence identified a novel type of C2H2 zinc finger. In Ros the peptide loop spacing of the zinc finger is 9 amino acids as opposed to the invariant 12 amino acids in the classical C2H2 motif. Site-directed mutagenesis of Cys-82 and His-92 in this motif showed that these residues are essential for Zn2+ and DNA binding activities of Ros. The existence of such a regulator in Agrobacterium may be due to horizontal interkingdom retrotransfer of the ros gene from plant to bacteria.
Review of renal carcinoma associated with Xp11.2 translocations/TFE3 gene fusions with focus on pathobiological aspect. (2012)

The concept of Xp11.2 renal cell carcinoma (RCC) was recently established as a tumor affecting 15% of RCC patients <45 years. Many patients present with advanced stage with frequent lymph node metastases. Histologically, Xp11.2 RCC is characterized by mixed papillary nested/alveolar growth pattern and tumor cells with clear and/or eosinophilic, voluminous cytoplasm. Neoplastic cells show intense nuclear immunoreactivity to TFE3, while focal immunostaining for melanocytic markers, including melanosome-associated antigen or Melan A in some cases, are also noted. Alpha smooth muscle actin and TFEB are consistently negative. Ultrastructurally, the ASPL-TFE3 RCC variant contains rhomboid crystals in the cytoplasm, similar to that observed in alveolar soft part sarcoma. The fusion of the TFE3 gene with several different genes, including ASPL(17q25), PRCC(1q21), PSF(1q34), NonO (Xq12) and CLTC (17q23) have been identified to date. The behavior of Xp11.2 RCC in children and young adults is considered as indolent even when diagnosed at advanced stage, including lymph node metastasis. However, Xp11.2 RCC in older patients behaves in a more aggressive fashion. Therapy includes nephrectomy with extended lymphadenectomy. There may be a role for new protease inhibitors in advanced inoperable disease. Further research is required to correlate clinical behavior with the expanding genetic spectrum of this tumor, and to establish standard therapy protocols for primary and metastatic lesions.
Production of Clinical-Type Dextran - Partial Hydrolytic Depolymerization and Fractionation of the Dextran from Leuconostoc mesenteroides Strain NRRL B-512 (1954)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTProduction of Clinical-Type Dextran - Partial Hydrolytic Depolymerization and Fractionation of the Dextran from Leuconostoc mesenteroides Strain NRRL B-512Ivan A. Wolff, C. L. Mehltretter, R. L Mellies, P. R. Watson, B. T. Hofreiter, P. L. Patrick, and C. E. RistCite this: Ind. Eng. Chem. 1954, 46, 2, 370–377Publication Date (Print):February 1, 1954Publication History Published online1 May 2002Published inissue 1 February 1954https://pubs.acs.org/doi/10.1021/ie50530a047https://doi.org/10.1021/ie50530a047research-articleACS PublicationsRequest reuse permissionsArticle Views91Altmetric-Citations21LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Determination of carbonyl‐containing functional groups in oxidized polyethylene (1984)

Abstract A combined (chemical and infrared (IR) spectrophotometric) method is discussed for the simultaneous determination of concentrations of carboxyl (A), ketone (K), and ester (E) groups formed in the oxidation of polyethylene (PE). The IR absorptivities of these functional groups were determined by using model compounds [stearic acid, stearone, poly‐(1,4‐butylene sebacate)]. The integral absorption of the CO band of polymer samples which contained several oxo groups of different types was found to be additive. This method was applied to the determination of the carboxyl, ester, and ketone content of samples oxidized at different oxygen pressures.
Candida-Infektionen bei Intensivpatienten (1991)

In 31 of 60 long-term ventilated intensive-care patients, a significant Candida antigen titer in serum was found that correlated with positive Candida cultures. In some cases the detection of the antigen was the first indication of Candida infection, while the isolation of the infectious agent required a culture period of 24-48 hours. In addition to routinely performed controls of Candida colonisation, determination of Candida antigen in the serum appears to be a valuable tool in the early diagnosis of candida infections.
II–VI quantum cascade emitters in the 6–8 μm range (2016)

We present the growth and characterization of ZnCdSe/ZnCdMgSe quantum cascade (QC) heterostructures grown by molecular beam epitaxy (MBE) and designed to operate at 6-8μm. These structures utilize the better-understood ZnCdMgSe with InP lattice matched compositions yielding a bandgap of 2.80 eV as compared to previous work which used ZnCdMgSe compositions with bandgaps at 3.00 eV. Grown structures posses good structural and optical properties evidenced in X-ray diffraction and photoluminescence studies. Fabricated mesa devices show temperature dependent I-V measurements with differential resistance of 3.6 Ω, and a turn on voltage of 11V consistent with design specifications. Electroluminescence was observed in these devices up to room temperature with emission centered at 7.1 μm and line widths of ∼16%(ΔE/E) at 80K. The results show that these are well-behaved electroluminescent structures. Addition of waveguide layers and further improvements in well barrier interfaces are being pursued in efforts to demonstrate lasing.
Template-assisted growth of rhodium nanowire contacts to silicon nanowires (2009)

Nanoscale materials are attracting growing interest due to their fascinating properties compared to the corresponding bulk materials, such as high effective surface area, catalytic activity and quantum confinement. Silicon nanowires, in particular, received much of this interest due to their promising applications in nano-electronics and nano-optoelectronics. Template synthesis, which involves a deposition into the nanopores of a nanoporous template, is considered among the easiest and least expensive approaches to fabricate nanowires with uniform diameters over a large area. More interestingly, it opens an opportunity to confine a nanocontact in the template's pores via a sequentional deposition of different materials. Herein, we describe a templatebased approach to fabricate metallic nanowire contacts to silicon nanowires. The metallic part of the nanowire (herein is rhodium) was deposited electrochemically within the pores of the template. However, the other (silicon) part was grown using the metal-catalysed vapour-liquid-solid (VLS) mechanism. The influence of the growth parameters on the structural quality of the nanowire was addressed.
Salicylic acid‐derived poly(anhydride‐esters) inhibit bone resorption and formation in vivo (2005)

The objective of this study was to investigate the effects of a novel polymer that biodegrades into salicylic acid (SA) on the healing of critical sized long bone defects. Microspheres of the homopolymer, or a copolymer containing 50% less of the SA, were packed into 5-mm mid-diaphyseal defects in rat femurs. Control animals received collagen sponge implants. After 4 and 8 weeks of implantation, bone healing was evaluated using microradiography and quantitative histomorphometry. Four weeks postsurgery, significantly less new bone was formed in both of the polymer groups (p<0.038). Reduced bone loss was also noted with the polymers at this time, although it was not statistically significant. However, at 8 weeks postsurgery, a statistically significant reduction in bone loss was observed in both of the polymer groups compared with controls (p<0.0072). Both polymers seemed to elicit identical tissue responses because there were no differences detected between the homopolymer and copolymer materials at either time point. These results indicate that locally released SA can significantly reduce both bone loss and bone formation in this animal model.
Synchronization of a “Plug-and-Simulate”-capable Co-Simulation of Internet-of-Things-Components (2019)

Modern production systems often form Internet-of-Things-systems (IoT). Because of the flexibility those systems are dynamic, meaning the entering of components during runtime, and heterogeneous. For the simulation of such systems, those challenges of dynamic and heterogeneity have to be met by a dynamic co-simulation. An important aspect of a co-simulation is the synchronization of the used simulations. In this contribution, challenges of synchronizing a co-simulation of IoT-systems are introduced and existing co-simulation synchronization concepts examined with regard to their usability for simulating IoT-systems. Afterwards a synchronization concept is presented, which can be used in the presented agent-based co-simulation concept.
Prevalence of theeaeA gene in verotoxigenicEscherichia colistrains from dairy cattle in Southwest Ontario (1996)

This study determined the prevalence of the eaeA gene and its relationship to serotype and type of verotoxin produced in a collection of 432 verotoxigenic Escherichia coli (VTEC) obtained from the faeces of healthy cows and calves in a systematic random survey involving 80 dairy farms in Southwest Ontario. A PCR amplification procedure involving primer pairs which target the conserved central region of the O157:H7 eaeA gene showed that 151 (35.2%) strains were positive for the eaeA gene. All isolates (9-21 for each O group) of O groups 5, 26, 69, 84, 103, 111, 145 and 157 were positive, whereas all isolates (7-34 for each O group) of O groups 113, 132, and 153 and serotype O156:NM (38 isolates) were negative for eaeA. Seventy-three percent of 130 isolates of eaeA-positive serotypes produced VT1 only compared with 20% of 253 isolates of eaeA-negative serotypes. We conclude that there is a strong association between certain O groups and the eaeA gene, that serotypes of eaeA-positive and eaeA-negative VTEC implicated in human and cattle disease are present at high frequency in the faeces of healthy cattle, that VT1 is more frequently associated with eaeA-positive than with eaeA-negative serogroups, and that the eaeA gene is more frequently found in VTEC from calves compared with VTEC from adult cattle.
Phonon transport in electronic devices: From diffusive to ballistic regime (2008)

This paper presents a Lattice Boltzmann Model applied to phonon transport in silicon-based films, implemented with the OpenLB library [1]. This model is based on the discretization of Boltzmann equation with the “gray” model for phonons. By this approach we can treat heat transfer in complex structures and various materials. We have validated our model by comparing temperature profiles and thermal conductivities in thin films to literature data. Finally, we discuss an improvement of the method in the ballistic case.
Personalized reference intervals for platelet count reduce the number of subjects with unexplained thrombocytopenia (2015)

Personalized reference intervals for platelet count reduce the number of subjects with unexplained thrombocytopenia
Biodistribution and kinetics of radiolabelled pyrrolidino-4-iodo-tamoxifen: prospects for pharmacokinetic studies using PET. (1994)

With a view to evaluating the role of PET imaging in early clinical studies of new anticancer drugs, we are investigating the recently developed antiestrogen compound pyrrolidino-4-iodo-tamoxifen (idoxifene). Preliminary experimental studies have been undertaken using [125,131I]idoxifene, following synthesis of a tributyl-stannyl-idoxifene precursor to facilitate radioiodination. We have investigated the tissue biodistribution and kinetics of [125I]idoxifene following i.v. infusion in hooded rats bearing the hormone-dependent transplantable mammary tumour OES.HR1. Clearance of idoxifene from the circulation is accompanied by an increase in uptake by tumour and uterus, to peak levels after 24 hours (0.33 +/- 0.037% dose/g (mean +/- 1 SD) and 0.40 +/- 0.033% dose/g, respectively). Highest uptake of idoxifene was found in the liver (11.0 +/- 0.8% dose/g), with a progressive fall after 24 hours consistent with hepatobiliary excretion of the radiotracer. No evidence of idoxifene metabolism was found in tissue extracts taken up to 48 hours. Whole body clearance of [131I]idoxifene was characterised by a single exponential decay (t1/2 = 140 hours) up to 350 hours post administration. We conclude that 124I-labelled idoxifene combined with PET imaging would facilitate human in vivo pharmacokinetic studies of this new anticancer drug and provide an opportunity to investigate relationships between drug uptake and tumour response.
Combination of bortezomib, thalidomide, and dexamethasone in the treatment of relapsed, refractory IgD multiple myeloma (2005)

The use of the proteasome inhibitor bortezomib has been recently introduced into the treatment of relapsed, refractory multiple myeloma (MM). We here demonstrate a case of a patient with IgD MM who was successfully treated with a combination of bortezomib, thalidomide, and dexamethasone. Relapse of the disease occurred following tandem autologous transplantation and was refractory to a salvage therapy consisting of thalidomide, cyclophosphamide, etoposide, and dexamethasone. While the administration of thalidomide was continued, the addition of bortezomib and dexamethasone led to a complete remission after 2 cycles of therapy. The feasibility of this treatment is supported by a recently reported phase I/II trial that used a lower dose of thalidomide in combination with an equal dose of bortezomib. This is the first report of a patient with IgD MM treated accordingly, suggesting that this entity is highly sensitive to the novel therapy.
Carbon‐13 spin–lattice relaxation in some polyfluoroaromatic compounds (1981)

Abstract Carbon‐13 chemical shifts, spin‐lattice relaxation times and nuclear Overhauser enhancement factors are reported for five polyfluoroaromatic compounds at 28°C. In all cases the relaxation of the fluorine bearing carbon is predominantly dipolar. Effective correlation times are smaller than those of the analogous benzene derivatives by a factor of 3–4, in qualitative agreement with predictions from the Stokes–Einstein diffusion theory. The T 1 values for the para ‐carbon of monosubstituted fluorobenzenes is clearly shorter than the T 1 values for the ortho ‐ and meta ‐carbons. This phenomenon was traced to anisotropic tumbling, and D ∥ and D⊥ diffusion coefficients were computed using Woessner's equations for molecules assumed to behave like symmetric rotors about their C 2 in‐plane principal symmetry axis. Equal tumbling ratios, D ∥/ D ⊥, were found in this way for toluene and perfluorotoluene.
Rational Design of Nanoporous MoS2/VS2 Heteroarchitecture for Ultrahigh Performance Ammonia Sensors (2019)

2D transition metal dichalcogenides (TMDs) have received widespread interest by virtue of their excellent electrical, optical, and electrochemical characteristics. Recent studies on TMDs have revealed their versatile utilization as electrocatalysts, supercapacitors, battery materials, and sensors, etc. In this study, MoS<sub>2</sub> nanosheets are successfully assembled on the porous VS<sub>2</sub> (P-VS<sub>2</sub> ) scaffold to form a MoS<sub>2</sub> /VS<sub>2</sub> heterostructure. Their gas-sensing features, such as sensitivity and selectivity, are investigated by using a quartz crystal microbalance (QCM) technique. The QCM results and density functional theory (DFT) calculations reveal the impressive affinity of the MoS<sub>2</sub> /VS<sub>2</sub> heterostructure sensor toward ammonia with a higher adsorption uptake than the pristine MoS<sub>2</sub> or P-VS<sub>2</sub> sensor. Furthermore, the adsorption kinetics of the MoS<sub>2</sub> /VS<sub>2</sub> heterostructure sensor toward ammonia follow the pseudo-first-order kinetics model. The excellent sensing features of the MoS<sub>2</sub> /VS<sub>2</sub> heterostructure render it attractive for high-performance ammonia sensors in diverse applications.
Synthesis of 3a,4,5,6,7a‐Hexahydro‐3a‐hydroxy‐3‐substitutedamino‐2‐benzothiazolinethiones and Related Compounds (1986)

Abstract The reaction of various potassium or ammonium salts [RNHC(=S)SM, M = K or NH 4 ; R = N(CH 3 ) 2 , morpholino, pyrrolidino, piperidino, and hexahydro‐1‐(1 H )‐acepinyl] with 2‐chlorocyclohexanone in alcohol at 25–30° afforded the title compounds 1 and 3–6 . The treatment of these compounds with a catalytic amount of p ‐toluenesulfonic acid in refluxing benzene furnished the dehydrated products 2 and 7–10 . The reaction of potassium dithiocarbazate with 2‐chlorocyclohexanone or 3‐chloro‐3,4‐pentanedione in refluxing ethanol afforded 11 , a six membered heterocycle and 12 , a five membered heterocycle, respectively. Possible mechanisms and supporting nmr, ir, uv mass spectral data are discussed.
Ultrafast Reflection Control based on Photoinduced Complex Refractive Index Changes in Guided Mode Thin Films Containing Indium Phthalocyanine (2001)

Abstract Ultrafast all-optical reflection control was achieved by complex refractive index changes upon photoexcitation of indium phthalocyanine in a guided mode geometry device. It gave a few microseconds response mostly characteristic to the lifetime of the excited triplet state.
The incidence and significance of anti-natalizumab antibodies (2007)

The incidence of persistent antibody positivity associated with natalizumab is 6%. Reduced clinical efficacy is apparent in persistently positive patients. Patients with a suboptimal clinical response or persistent infusion-related adverse events should be considered for antibody testing.
"Science and Religion, Contemporary Scientific Views on Gnosticism, Heresy, Mystic Codes in Great works of Art and Gnostic Symbols such as Discussed in “Code daVinchi” etc" (2020)

Books like daVinchi Code catch attention of millions of people while at the same time their success puzzle many of us: why ancient ideas, explored for millennia still catch attention of so many people? Here I suggest the reason: this attention relates to the most fundamental unresolved problem of contemporary science and even more, of the entire contemporary culture. This is a question of the fundamental breakdown between science and religion, the failure of the culture to repair this split between two of its most important endeavors. Science appeared at the time of Newton, near 300 years ago, and acquired so much significance that in a recently short time the perceived contradiction between science and religion significantly reduced importance of religion. Some scientists like Dawkins deny religion at all.