gebhart/patrepeval huggingface dataset:
Applying ATM/AAL2 as a switching technology in third-generation mobile access networks (1999)

In this article we focus on the transport and switching part of third-generation mobile access networks and outline some important aspects of applying ATM in these networks. In particular, we argue that in order for the mobile access network to support low-bit-rate delay-sensitive traffic consisting of short packets, the standardization of a new ATM adaptation layer, AAL2, and associated signaling protocol has been necessary. The AAL2 protocol has been designed to support low-bit-rate delay-sensitive services (typically compressed voice) where other adaptation layers fail to deliver the required QoS and maintain efficient resource utilization at the same time. Furthermore, in order to provide mobility and soft handover support in W-CDMA-based mobile networks such as UMTS or IMT-2000, there is also a strong demand for fast connection establishment and release. Therefore, when designing ATM-based cellular access networks some specific architectural and traffic management issues need to be addressed.
Models for Nociception Stimulation and Memory Effects in Awake and Aware Healthy Individuals (2018)

A device and methodology for noninvasive for detecting nociception stimulation have been developed. The proposed method and models have been validated on healthy volunteers.
Advanced Multifluid and Collisional-Radiative Models for Laser-Plasma Interaction (Briefing Charts) (2014)

Abstract : Table of Contents: Motivation, Plasma M&S & CR kinetics, Level grouping, Multi-fluid equations & LPI, Beyond translational equilibrium, and Summary & future work. Conclusion: Multiscale algorithms for nonequilibrium flows with CR kinetics. Level grouping schemes of electronic states of atoms. Multi-fluid equations developed to efficiently capture electron hydrodynamics . Particle merge/split for particle management, efficient sampling, inelastic collisions. Ongoing works: Multi-D simulation with level grouping, Modeling of inelastic collisions in multi-fluid, and High-order particle merging schemes.
The Impact of PRRS on the Pig Cost of Production (2005)

Porcine Reproductive and Respiratory Syndrome (PRRS) has had a significant impact on the profitability of swine production. As a means to quantify the financial impact of PRRS to the U.S. swine industry, a study was conducted. This study utilized case studies and a Delphi survey to identify the various impacts PRRS has on farms. Results suggest that impacts to individual farms vary greatly but aggregated data for approximately 100 million market swine being sold each year in the U.S., estimates PRRS adds somewhere between $5.60 and $7.62 to the cost per head sold.
A computerized rotating laminar radionuclide camera. (1979)

We have constructed a radionuclide camera that embodies a unique detector-collimator concept and provides a radically new approach to imaging. The heart of the instrument is a linear array of semiconductor detectors separated by thin tungsten plates that confine the field of view of each detector to one dimension. This collimator design has a higher collection efficiency than the standard parallel-hole collimator but cannot directly produce a two-dimensional image. When multiple measurements are taken as the array rotates through 180 degrees, a computerized image restoration algorithm can then produce two-dimensional images with resolution determined by the width of the detectors. A small prototype camera has produced images with resolution superior to conventional Anger cameras.
Collision Detection and Control of Single-link Flexible Arm Using Optimal Disturbance Decoupling and Kalman Filters (2012)

This paper describes a method using coupled state estimators for collision detection and control of a single-link flexible arm. To improve the control performance of the flexible arm with an innovation-based collision detection system when unobserved obstacles collide with the arm’s side, we introduce an Optimal Disturbance Decoupling Filter that decouples undesired collision force effects from the estimation error. The controller generates a control torque based on the state estimate by using the Optimal Disturbance Decoupling Filter. Collision detection is then realized through the innovation of a Kalman filter. The proposed system prevents deterioration of the control performance when collision occurs.
Antibodies to synthetic peptides based on band 3 motifs react specifically withPlasmodium falciparum(humanmalaria)-infected erythrocytes and block cytoadherence (1994)

Rabbit polyclonal and mouse monoclonal antibodies (Mabs) prepared against synthetic peptides patterned on exofacial loops 3 (amino acids 546-555) and 7 (821-834) of the human anion transport protein band 3 inhibited the cytoadherence of Plasmodium falciparum-infected erythrocytes to C32 amelanotic melanoma cells. Mabs directed against exofacial loop 4 (amino acids 628-642) did not inhibit adherence to a significant degree. The murine Mabs recognized only P. falciparum-infected cryptic in uninfected erythrocytes.
Thin Polymer Layers Formed Using Multiarm Poly(ethylene glycol) Vinylsulfone by a Covalent Layer-by-Layer Method (2007)

ADVERTISEMENT RETURN TO ISSUEPREVNoteThin Polymer Layers Formed Using Multiarm Poly(ethylene glycol) Vinylsulfone by a Covalent Layer-by-Layer MethodJinku Kim, Bradley K. Wacker, and Donald L. ElbertView Author Information Departments of Chemical Engineering and Biomedical Engineering and Center for Materials Innovation, Washington University in St. Louis, St. Louis, Missouri 63130 Cite this: Biomacromolecules 2007, 8, 11, 3682–3686Publication Date (Web):October 12, 2007Publication History Received9 July 2007Revised29 August 2007Published online12 October 2007Published inissue 1 November 2007https://pubs.acs.org/doi/10.1021/bm700756zhttps://doi.org/10.1021/bm700756zbrief-reportACS PublicationsCopyright © 2007 American Chemical SocietyRequest reuse permissionsArticle Views777Altmetric-Citations19LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Alcohols,Cell physiology,Layer by layer deposition,Layers,Thin films Get e-Alerts
HLA sensitisation: can it be prevented? (2014)

Human leukocyte antigen (HLA) sensitisation occurs after transfusion of blood products and transplantation. It can also happen spontaneously through cross-sensitisation from infection and pro-inflammatory events. Patients who are highly sensitised face longer waiting times on organ allocation programmes, more graft rejection and therefore more side effects of immunosuppression, and poorer graft outcomes. In this review, we discuss these issues, along with the limitations of modern HLA detection methods, and potential ways of decreasing HLA antibody development. We do not discuss the removal of antibodies after they have developed.
Reconstruction Algorithm Based on Bregman Iteration (2013)

In this paper,we present a new reconstruction model based on l1 regularization and TV constraint conditions in the large scale integrated circuit field.And then,we give the new reconstruction algorithm to the new model based on Bregman iteration.The new algorithm consists of two steps.1) We take the l1-norm of image as the regularization item and weighted l2-norm of image error as the fidelity item,and solve this constrained optimization problem using the Bregman iteration;2) We make further improvement using TV constraint to the reconstructed image obtained by Step 1).The new algorithm separates the above two steps,so,it reduces the complexity of the algorithm and accelerates the convergence rate.In the end,we apply the new algorithm to the classic Shepp-Logan mode and a circuit board image.Experimental results show that the advantage of the new algorithm on reconstruction speed is obvious and the reconstruction quality is good.
A poor perspective of self weight significantly increases adverse outcomes in non-alcoholic fatty liver disease (NAFLD) (2022)

This study highlights the positive association between appropriate weight perception and better outcomes in individuals with NAFLD. Poor weight perception increased the risk of adverse events and decreased inclination toward seeking weight loss treatment. Greater emphasis should be placed on dealing with weight perception in individuals with NAFLD for better treatment outcomes.
A Note on the Accuracy of Calibration of a Fifth Wheel (1977)

Abstract A series of experiments were carried out using a fifth wheel to determine how accurate the wheel was when using different calibration methods. The methods are described and the results analyzed to determine the effects of method and speed. It was found that the methods of calibration were not significantly different but the tests were speed‐dependent.
Molecular structure of frizzled, a Drosophila tissue polarity gene. (1990)

The function of the frizzled (fz) locus is required to coordinate the cytoskeletons of pupal epidermal cells so that a parallel array of cuticular hairs and bristles is produced. We report here the molecular cloning and characterization of the fz locus. The locus is very large. Mutations that inactivate the gene are spread over 100 kb of genomic DNA. The major mRNA product of the gene is a 4-kb RNA that is encoded by 5 exons spread over more than 90 kb of genomic DNA. Conceptual translation of this mRNA indicates that it encodes an integral membrane protein that is likely to contain both extracellular and cytoplasmic domains.
Myocardial ischemic memory: why and how to investigate it? Insights from nuclear medicine (2018)

Les syndromes coronaires aigus constituent l'une des principales causes d'urgences mdicales. L'incertitude diagnostique en cas de syndrome coronaire aigu non ST+ est responsable d'une augmentation de la morbi-mortalit et de surcots substantiels. En consquence, des outils diagnostiques prcoces et spcifiques apparaissent ncessaires pour explorer des pisodes ischmiques brefs, mme aprs rsolution de ceux-ci, dans ce qui est appel l'exploration de la mmoire ischmique . Plusieurs approches fonctionnelles non invasives ont t dveloppes, en particulier en imagerie nuclaire. Nous prsentons dans cette revue les principaux axes d'exploration de la mmoire ischmique myocardique par imagerie fonctionnelle, ainsi que les perspectives potentielles venir.
Alternating Copolymers of Carbazole and Triphenylamine with Conjugated Side Chain Attaching Acceptor Groups: Synthesis and Photovoltaic Application (2010)

10.1021/ma101491c
Isolation of high quality RNA from Phytophthora infestans for transcriptome analysis (2022)

Motivation and Aim: Phytophthora infestans is one of the main pests of agricultural plants of the Solanaceae family, especially potatoes: the cost of combating against pathogen can be up to 30 % of the product's final price. Studies of its transcriptome, especially transcriptome changes during the colonization of the host plant, can be very useful for the development of new highly selective and eco-friendly drugs for pest control. For such studies, it is necessary to develop methods for isolating high-quality RNA from P. infestans samples, which is significantly complicated by the presence of a rigid cell wall and aggressive RNAses. The aim of our work was to study the effect of various parameters on the quality of total RNA isolated from samples of P. infestans. Methods and Algorithms: To achieve this goal, we identified several key parameters that affect the integrity of total RNA during isolation: this is the process of sample preparation and grinding, as well as the use of RNA stabilizing solutions. The Plant MiniKit and Qiazol (Qiagen) were used to purify the RNA fraction. To optimize the protocol, we varied the above parameters and examined the obtained RNA using an RNA analyzer, the quality of the RNA was assessed based on the RNA integrity number (RIN). Results: RNA isolation should be carried out immediately after collection of P. infestans samples. Grinding P. infestans is best done with Tissue Lyser. However, the original Qiagen lysis buffers are insufficient to prevent RNA degradation during the homogenization. Best results were achieved with Qiazol added to the samples prior to the homogenization. The samples were then proceeded according to Qiazol protocol. Qiagen spin columns were used for RNA isolation after phase separation step. Tissue Lyser grinding time is critical: RIN was decreased with longer grinding.
Neuromuscular activation and motor-unit firing characteristics in cerebral palsy (2007)

Muscle strength, neuromuscular activation, and motor-unit firing characteristics (firing rate, recruitment, and short-term synchronization) were assessed during voluntary contractions of the medial gastrocnemius (GAS) and tibialis anterior (TA) muscles of 10 participants with spastic diplegic or hemiplegic cerebral palsy (CP). The participants (six females, four males; age range 6 to 37y) walked with equinus gait at Gross Motor Function Classification System levels II to III. These were compared with 10 age-matched controls (five females; age range 7 to 35y). Neuromuscular activation was estimated by the ratio of surface electromyogram amplitude to M-wave amplitude elicited by supramaximal electrical nerve stimulation. Participants with CP produced significantly less torque (normalized by leg length) compared with controls (TA: mean 2.3, SD 1.6 vs mean 8.9, SD 3.4N m/m; GAS mean 13.7, SD 7.1 vs mean 28.6, SD 5.1Nm/m, p<0.001). Neuromuscular activation during maximum voluntary contraction was significantly reduced in the participants with CP compared with controls (mean 2.4, SD 1.5 vs mean 9.7, SD 2.7Nm/m for TA; mean 1.04, SD 0.41 vs mean 3.1, SD 1.2Nm/m for GAS, p<0.001). When compared at the same submaximal level of neuromuscular activation, motor-unit recruitment and firing rates were not different between the groups, although short-term synchronization in TA was reduced in the participants with CP. These data indicate that weakness, known to be an important component of the motor deficit in CP, has a strong central component. Although the relation between recruitment and firing rate remained substantially intact at the low and moderate force contractions tested, results suggest that the participants with CP were unable to recruit higher threshold motor units or to drive lower threshold motor units to higher firing rates.
Kinetics and Modeling of Lactic Acid Production by Lactobacillus plantarum (1994)

An unstructured model was developed to describe bacterial growth, substrate utilization, and lactic acid production by Lactobacillus plantarum in cucumber juice. Significant lactic acid production occurred during growth, as well as stationary phases. The percentage of acid produced after growth ceased was a function of the medium composition. Up to 51% of the lactic acid was produced after growth ceased when NaCl was not present in the medium, whereas not more than 18% of the total lactic acid was produced after the growth ceased in presence of NaCl, probably because of an increase in the cell death rate. An equation relating the specific death rate and NaCl concentration was developed. With the kinetic model proposed by R. Luedeking and E. L. Piret (J. Biochem. Microbiol. Technol. Eng. 1:393-412, 1958) for lactic acid production rate, the growth-associated and non-growth-associated coefficients were determined as 51.9 (+/-4.2) mmol/g of cells and 7.2 (+/-0.9) mmol/g of cells h respectively. The model was demonstrated for batch growth of L. plantarum in cucumber juice. Mathematical simulations were used to predict the influence of variations in death rate, proton concentration when growth ceased, and buffer capacity of the juice on the overall fermentation process.
Cation Effect on Formation of Preyssler‐type 30‐Tungsto‐5‐phosphate: Enhanced Yield of Na‐encapsulated Derivative and Direct Synthesis of Ca‐ and Bi‐Encapsulated Derivatives (2015)

Abstract The effect of cations in a reaction mixture for the preparation of the Preyssler‐Jeannin‐Pope type 30‐tungsto‐5‐phosphate [P 5 W 30 O 110 Na] 14– is investigated. Reaction of phosphate and tungstate with a P/W ratio of ca. 3.9 in an acidic aqueous solution without cations selectively leads to the Dawson‐type 18‐tungsto‐2‐phosphate, [P 2 W 18 O 62 ] 6– . Amongst all the alkali cations, only Na + allows formation of the Preyssler‐type polyanion [P 5 W 30 O 110 Na] 14– , with an encapsulated Na + ion, and the product yield can be improved by increasing Na + amount. The presence of Li + ions instead results in the Dawson‐type polyanion [P 2 W 18 O 62 ] 6– , whereas K + , Rb + , and Cs + selectively result in the Keggin‐type polyanion [PW 12 O 40 ] 3– . An improved synthetic procedure for the Na + ‐encapsulated Preyssler‐ion leading to a higher isolated yield is presented. Furthermore, addition of Ca 2+ and Bi 3+ compounds allows formation of the Ca 2+ ‐ and Bi 3+ ‐encapsulated Preyssler‐type polyanions, [P 5 W 30 O 110 Ca] 13– and [P 5 W 30 O 110 Bi] 12– , respectively. Furthermore, single‐crystal XRD structure of the Bi 3+ ‐encapsulated Preyssler‐type polyanions, [P 5 W 30 O 110 Bi] 12– , is presented for the first time.
Modulation of Stem Cell Shape and Fate A: The Role of Density and Seeding Protocol on Nucleus Shape and Gene Expression (2008)

Mesenchymal stem cell shape and fate are intrinsic manifestations of form and function at the cellular level. We hypothesize that cell seeding density and initial seeding protocol influence stem cell shape and fate. Nucleus shape and early (within days of seeding) expression of genes typical for pre-, peri-, and postcondensation events were compared between groups of cells after seeding at or proliferating to target density (low density [LD], 16,500 cells/cm2; high density [HD], 35,000 cells/cm2; very high density [VHD], 86,500 cells/cm2). Significant differences in nuclear shape could be attributed to seeding protocol in the VHD group, where nuclei from cells that proliferated to VHD were significantly rounder than nuclei from cells seeded at target VHD. Furthermore, cells that proliferated to VHD exhibited significantly rounder nuclei than nuclei from all other cell density and seeding protocol groups. In contrast, nuclei from cells that were seeded at the VHD were flatter than nuclei from cells of all other groups. Furthermore, the significant rounding of nuclei in the cells that proliferated to VHD was accompanied by a two-, six-, and ninefold increase from baseline in Runx2, Sox9, and Aggrecan (AGC) expression, markers indicative of precondensation, peri-, and post-condensation events, respectively. None of the other groups showed significant changes in gene expression over baseline. Finally, seeding at target density results in greater overlap of cells compared to groups in which cells proliferate to target density, conferring increased thickness to multicellular culture aggregates seeded at target density. These data suggest that seeding protocols can be exploited to modulate mesenchymal stem cell shape and early gene expression typical for condensation events in development, which occur over an approximately 12-h period at E11.5 in the mouse limb bud. Follow-on studies will delineate longer-term effects of density and seeding protocol on modulation of stem cell fate and cell assembly to form tissues.
Ormeloxifene Suppresses Prostate Tumor Growth and Metastatic Phenotypes via Inhibition of Oncogenic β-catenin Signaling and EMT Progression (2017)

Abstract Ormeloxifene is a clinically approved selective estrogen receptor modulator, which has also shown excellent anticancer activity, thus it can be an ideal repurposing pharmacophore. Herein, we report therapeutic effects of ormeloxifene on prostate cancer and elucidate a novel molecular mechanism of its anticancer activity. Ormeloxifene treatment inhibited epithelial-to-mesenchymal transition (EMT) process as evident by repression of N-cadherin, Slug, Snail, vimentin, MMPs (MMP2 and MMP3), β-catenin/TCF-4 transcriptional activity, and induced the expression of pGSK3β. In molecular docking analysis, ormeloxifene showed proficient docking with β-catenin and GSK3β. In addition, ormeloxifene induced apoptosis, inhibited growth and metastatic potential of prostate cancer cells and arrested cell cycle in G0–G1 phase via modulation of cell-cycle regulatory proteins (inhibition of Mcl-1, cyclin D1, and CDK4 and induction of p21 and p27). In functional assays, ormeloxifene remarkably reduced tumorigenic, migratory, and invasive potential of prostate cancer cells. In addition, ormeloxifene treatment significantly (P &amp;lt; 0.01) regressed the prostate tumor growth in the xenograft mouse model while administered through intraperitoneal route (250 μg/mouse, three times a week). These molecular effects of ormeloxifene were also observed in excised tumor tissues as shown by immunohistochemistry analysis. Our results, for the first time, demonstrate repurposing potential of ormeloxifene as an anticancer drug for the treatment of advanced stage metastatic prostate cancer through a novel molecular mechanism involving β-catenin and EMT pathway. Mol Cancer Ther; 16(10); 2267–80. ©2017 AACR.
Slow light devices in III–V photonic crystals: state of the art and open issues (2011)

We review the properties of photonic crystals in III–V materials from the prospective of light-matter interaction enhanced by “slow-light”. We discuss some key functions, namely the generation of a time delay and the nonlinear conversion. Compared to optical fibers, the typical scales, dispersion and nonlinear lengths are reduced to the mm range, thereby opening the possibility of on-chip all optical processing. That has been enabled by the minimisation of linear and nonlinear losses.
Welcome to Neurology: Genetics (2015)

The powers of human genetics and genetic technologies have transformed the complexities of neurology and neuroscience at the basic, translational, and now also the clinical level. We have left an era of black and white views of causative genetic variation and are entering a period of more than 50 shades of grey, fascinated with DNA variants that increase or decrease risk, epigenetic modification, and an unexpectedly large number of variants of unknown or potentially pathogenic significance. Loss-of-function alleles and even complete human gene knockouts for certain genes appear to be compatible with a normal phenotype.
Revealing the defect-dominated oxygen evolution activity of hematene (2020)

Oxygen electrocatalysis is vital for advanced energy technologies, but inordinate challenges remain due to the lack of highly active earth-abundant catalysts.
Risk-stratified surveillance and cost effectiveness of follow-up after radical cystectomy in patients with muscle-invasive bladder cancer (2017)

Risk-score-stratified surveillance protocol has potential to reduce over-evaluation after radical cystectomy without adverse effects on medical cost.