gebhart/patrepeval huggingface dataset:
Mass of left ventricular myocardium estimated with dynamic spatial reconstructor (1984)

Using the Dynamic Spatial Reconstructor (DSR), a unique multiple X-ray source, high-repetition-rate CAT scanner, we estimated left ventricular (LV) myocardial volume and chamber volume of eight dogs ranging from 2.5 to 32.5 kg. Dogs were given subcutaneous morphine (3 mg/kg) and anesthetized with intravenous pentobarbital sodium (22 mg/kg). A bolus of 1 ml/kg body wt contrast medium was injected into the superior vena cava and 60/s scans repeated over 7 s were performed. Each 0.0167-s scan generated image data for 120 1.8-mm-thick transverse slices, in the dextro and levo phases of the angiograms. Retrospective reformatting of the scan data was used to generate images of thin slices perpendicular to the aortoapical axis of the LV. The LV muscle and chamber volumes were estimated from their outlines in each imaged slice using a manually operated trackball interfaced to a computer. Values of the LV muscle ranged from 18.0 to 146.8 cm3 by DSR and showed a good correlation with the postmortem values (r = 0.99, y = 0.94x + 4.1). Ratios of volume of the myocardium to chamber volume ranged from 1.19 to 3.10.
Deferred Data-Flow Analysis : Algorithms, Proofs and Applications (1998)

Loss of precision due to the conservative nature of compile-time dataflow analysis is a general problem and impacts a wide variety of optimizations. We propose a limited form of runtime dataflow analysis, called deferred dataflow analysis (DDFA), which attempts to sharpen dataflow results by using control-flow information that is available at runtime. The overheads of runtime analysis are minimized by performing the bulk of the analysis at compile-time and deferring only a summarized version of the dataflow problem to runtime. Caching and reusing of dataflow results reduces these overheads further. DDFA is an interprocedural framework and can handle arbitrary control structures including multiway forks, recursion, separately compiled functions and higher-order functions. It is primarily targeted towards optimization of heavy-weight operations such as communication calls, where one can expect significant benefits from sharper dataflow analysis. We outline how DDFA can be used t...
Uncovering Halide Mixing and Octahedral Dynamics in Vacancy-Ordered Double Perovskites by Multinuclear Magnetic Resonance Spectroscopy (2021)

Vacancy-ordered double perovskites Cs2SnX6 (X = Cl, Br, I) have emerged as promising lead-free and ambient-stable materials for photovoltaic and optoelectronic applications. To advance these promising materials, it is crucial to determine the correlations between physical properties and their local structure and dynamics. Solid-state NMR spectroscopy of multiple NMR-active nuclei (133Cs, 119Sn and 35Cl) in these cesium tin(IV) halides has been used to decode the structure, which plays a key role in the materials’ optical properties. The 119Sn NMR chemical shifts span approximately 4000 ppm and the 119Sn spin-lattice relaxation times span three orders of magnitude when the halogen goes from chlorine to iodine in these diamagnetic compounds. Moreover, ultrawideline 35Cl NMR spectroscopy for Cs2SnCl6 indicates an axially symmetric chlorine electric field gradient tensor with a large quadrupolar coupling constant of ca. 32 MHz, suggesting a chlorine that is directly attached to Sn(IV) ions. Variable temperature 119Sn spin lattice relaxation time measurements uncover the presence of hidden dynamics of octahedral SnI6 units in Cs2SnI6 with a low activation energy barrier of 12.45 kJ/mol (0.129 eV). We further show that complete mixed-halide solid solutions of Cs2SnClxBr6−x and Cs2SnBrxI6−x (0 ≤ x ≤ 6) form at any halogen compositional ratio. 119Sn and 133Cs NMR spectroscopy resolve the unique local SnClnBr6−nand SnBrnI6−n (n = 0−6) octahedral and CsBrmI12−m (m = 0−12) cuboctahedral environments in the mixed-halide samples. The experimentally observed 119Sn NMR results are consistent with magnetic shielding parameters obtained by density functional theory computations to verify random halogen distribution in mixed-halide analogues. Finally, we demonstrate the difference in the local structures and optical absorption properties of Cs2SnI6 samples prepared by solvent-assisted and solvent-free synthesis routes.
Synthesis of Indolizines and Heterocyclic Chalcones Catalyzed by Supported Copper Nanoparticles (2013)

Solvent decides: Versatile copper nanoparticles (Cu NPs) on activated carbon have been found to catalyze the multicomponent synthesis of indolizines in dichloromethane and the synthesis of heterocyclic chalcones in the absence of solvent, in both cases, from pyridine-2-carbaldehyde derivatives, secondary amines, and terminal alkynes (see scheme).
JunD suppresses bone formation and contributes to low bone mass induced by estrogen depletion (2008)

JunD is an activator protein-1 (AP-1) component though its function in skeletal system is still not fully understood. To elucidate the role of JunD in the regulation of bone metabolism, we analyzed JunD-deficient mice. JunD deficiency significantly increased bone mass and trabecular number. This bone mass enhancement was due to JunD deficiency-induced increase in bone formation activities in vivo. Such augmentation of bone formation was associated with simultaneous increase in bone resorption while the former was dominant over the latter as accumulation of bone mass occurred in JunD-deficient mice. In a pathological condition relevant to postmenopausal osteoporosis, ovariectomy reduced bone mass in wild type (WT) mice as known before. Interestingly, JunD deficiency suppressed ovariectomy-induced increase in bone resorption and kept high bone mass. In addition, JunD deficiency also enhanced new bone formation after bone marrow ablation. Examination of molecular bases for these observations revealed that JunD deficiency enhanced expression levels of c-jun, fra-1, and fra-2 in bone in conjunction with elevated expression levels of runx2, type I collagen, and osteocalcin. Thus, JunD is involved in estrogen depletion-induced osteopenia via its action to suppress bone formation and to enhance bone resorption.
Deactivation of a Hydrophobic Pt/SDBC Catalyst by Nitrogen Compounds for Hydrogen Isotopic Exchange Reaction. (1995)

水素同位体分離に用いられる疎水性Pt触媒の活性に対する硝酸, 硝酸塩および酸化窒素などの不純物の影響を評価するために, これらの窒素化合物を反応物に混入して同位体交換反応速度の経時変化を測定し, 触媒活性サイトの収支に基づいて活性劣化機構を検討した.その結果, HNO3は可逆的な被毒を示し, 硝酸被毒による触媒活性劣化速度はZeldovich速度式により解析することができた. Sr (NO3) 2のような中性の硝酸塩は触媒活性に殆ど影響せず, ZrO (NO3) 2のような加水分解により酸性を呈する硝酸塩はHNO3と類似な被毒挙動を示した. また, NO, NO2, NH3は何れも触媒を被毒せず, 逆にNOまたはNO2による H2/HDO 間の交換反応の促進効果が認められた. これはNO, NO2とH2間の発熱反応に伴う触媒表面の局部的な温度上昇に基づくものと推察された.
Targeting inflammatory pathways in myocardial infarction (2013)

Acute cardiomyocyte necrosis in the infarcted heart generates damage-associated molecular patterns (DAMPs), activating complement and Toll-Like Receptor (TLR)/Interleukin (IL)-1 signalling and triggering an intense inflammatory reaction. Infiltrating leucocytes clear the infarct from dead cells, while activating reparative pathways that lead to formation of a scar. As the infarct heals the ventricle remodels, the geometric, functional and molecular alterations associated with postinfarction remodelling are driven by the inflammatory cascade and are involved in the development of heart failure. Because unrestrained inflammation in the infarcted heart induces matrix degradation and cardiomyocyte apoptosis, timely suppression of the postinfarction inflammatory reaction may be crucial to protect the myocardium from dilative remodelling and progressive dysfunction. Inhibition and resolution of postinfarction inflammation involve mobilization of inhibitory mononuclear cell subsets and require activation of endogenous STOP signals. Our manuscript discusses the basic cellular and molecular events involved in initiation, activation and resolution of the postinfarction inflammatory response, focusing on identification of therapeutic targets. The failure of anti-integrin approaches in patients with myocardial infarction and a growing body of experimental evidence suggest that inflammation may not increase ischaemic cardiomyocyte death, but accentuates matrix degradation causing dilative remodelling. Given the pathophysiologic complexity of postinfarction remodelling, personalized biomarker-based approaches are needed to target patient subpopulations with dysregulated inflammatory and reparative responses. Inhibition of pro-inflammatory signals (such as IL-1 and monocyte chemoattractant protein-1) may be effective in patients with defective resolution of postinfarction inflammation who exhibit progressive dilative remodelling. In contrast, patients with predominant hypertrophic/fibrotic responses may benefit from anti-TGF strategies.
Review of lasers and aesthetic medicine on five continents (2010)

From 10 to 12 September 2009, over 300 delegates, 90 faculty members and 45 vendors (with over 400 individuals present), came together for the Inaugural Lasers and Aesthetic Medicine on Five Continents Congress, which took place in Nice, France. The meeting venue, the Palais de la Mediterranean, welcomed the delegates and industry members with three full days of incredible lectures from dermatologists and plastic surgeons from all over the world; thus, the concept of the Five-Continent Congress was born.
Espíritu indomable de la literatura venezolana: Ana Teresa Torres (2002)

Su nombre destaca dentro del ambiente literario en Venezuela. Psicoanalista y novelista, esta escritora ha sabido calar en los gustos de muchos lectores nacionales e internacionales. Su mayor pasion ha sido escribir, y ello le ha valido distintos premios, entre ellos el otorgado por el premio de la fundacion alemana Anna Seghers, quien fuera en vida una de las narradoras alemanas mas importantes del siglo XX.
Effect of natural naphthoquinones in BALB/c mice infected with Leishmania amazonensis and L. venezuelensis. (1992)

Plumbagin, 3,3'-biplumbagin and 8,8'-biplumbagin are naphthoquinones isolated by activity-directed fractionation from a Bolivian plant, Pera benensis, used in folk medicine as treatment of cutaneous leishmaniasis caused by Leishmania braziliensis. BALB/c mice were infected with L. mexicana or L. venezuelensis and treated 24 h after the parasitic infection with plumbagin (5 or 2.5 mg/kg/day), 3,3'-biplumbagin, 8,8'-biplumbagin (25 mg/kg/d) or Glucantime (200 mg/kg/d). Lesion development was the criteria employed to evaluate the inhibitory effect. The bis-naphthoquinones were less potent than Glucantime against L. amazonensis and L. venezuelensis. Plubagin and Glucantime delayed the development of L. amazonensis and L. venezuelensis. Assays of a single local treatment on foot-pad infection two weeks after the parasitic inoculation with L. amazonensis showed that 8,8'-biplumbagin (50 mg/kg/d) was as potent as Glucantime (400 mg/kg/d).
Zero-field magnetic susceptibility study of the magnetic phase transition in the two-dimensional ionic ferromagnet bis(benzylammonium) tetrabromochromate(II), (C6H5CH2NH3)2CrBr4 (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTZero-field magnetic susceptibility study of the magnetic phase transition in the two-dimensional ionic ferromagnet bis(benzylammonium) tetrabromochromate(II), (C6H5CH2NH3)2CrBr4Carlo Bellitto, Pasquale Filaci, and Salvatore PatrizioCite this: Inorg. Chem. 1987, 26, 1, 191–194Publication Date (Print):January 1, 1987Publication History Published online1 May 2002Published inissue 1 January 1987https://doi.org/10.1021/ic00248a037RIGHTS & PERMISSIONSArticle Views378Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (435 KB) Get e-Alerts Get e-Alerts
Thermal emission from finite photonic crystals (2010)

We present a microscopic theory of thermal emission from truncated photonic crystals and show that spectral emissivity and related quantities can be evaluated via standard bandstructure computations without any approximation.We then analyze the origin of thermal radiation enhancement and suppression inside photonic crystals and demonstrate that the central quantity that determines the thermal radiation characteristics such as intensity and emissive power is the area of the iso-frequency surfaces and not the density of states as is generally assumed.We also identify the physical mechanisms through which interfaces modify the potentially super-Planckian radiation flow inside infinite photonic crystals, such that thermal emission from finite-sized samples is consistent with the fundamental limits set by Planck's law.As an application, we further demonstrate that a judicious choice of a photonic crystal's surface termination facilitates considerable control over both the spectral and angular thermal emission properties.Finally, we outline design principles that allow the maximization of the radiation flux, including effects associated with the isotropy of the effective Brillouin zone, photonic band gap size and flatness of the band structure in the spectral range of interest.
Theoretical and experimental study of Third Order Difference Frequency Generation (2007)

We performed several experimental validations of a model based on Jacobi elliptic functions describing collinear phase-matched third order difference frequency generation without spatial and temporal walk-off. The experiments used KTP crystals and sub-nanosecond laser beams.
Evidence for an increase in the cadmium content of herbage since the 1860s (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEvidence for an increase in the cadmium content of herbage since the 1860sKevin C. Jones, Andrew Jackson, and A. E. JohnstonCite this: Environ. Sci. Technol. 1992, 26, 4, 834–836Publication Date (Print):April 1, 1992Publication History Published online1 May 2002Published inissue 1 April 1992https://pubs.acs.org/doi/10.1021/es00028a026https://doi.org/10.1021/es00028a026research-articleACS PublicationsRequest reuse permissionsArticle Views101Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Statistical rock physics: Combining rock physics, information theory, and geostatistics to reduce uncertainty in seismic reservoir characterization (2001)

This paper presents snapshots of current and emerging trends in applied statistical rock physics for reservoir characterization. By integrating fundamental concepts and models of rock physics, statistical pattern recognition, and information theory with seismic inversion and geostatistics, we can quantify and reduce uncertainties in reservoir management. Rock physics allows us to link seismic response and reservoir properties and to extend the available data to generate training data for the classification system.
Design of polymer-based asymmetric membranes and compartmentalized vesicles (2020)

International audience
A pentatricopeptide repeat protein restores nap cytoplasmic male sterility in Brassica napus (2017)

Two forms of male-sterile cytoplasm, designated nap and pol, are found in the oilseed rape species, Brassica napus. The nap cytoplasm is observed in most B. napus varieties, and it confers male sterility on a limited number of cultivars that lack the corresponding restorer gene, Rfn. In the present study, using linkage analysis in combination with 5652 BC1 progeny derived from a cross between a nap cytoplasmic male sterility (CMS) line 181A and a restorer line H5, we delimited the Rfn gene to a 10.5 kb region on chromosome A09, which contained three putative ORFs. Complementation by transformation rescue revealed that the introduction of ORF2, which encodes a pentatricopeptide repeat (PPR) protein, resulted in the recovery of fertility of nap CMS plants. Expression analysis suggested that the Rfn was highly expressed in flower buds and it was preferentially expressed in the tapetum and meiocytes during anther development. Further RNA gel blots and immunodetection suggested that the Rfn gene may play a complicated role in restoring the nap CMS. Our work laid the foundation for dissecting the molecular basis of CMS fertility restoration and the nuclear-mitochondrial interactions in CMS/Rf systems.
Season‐Long Effects of Chilling Treatments Applied to Germinating Cottonseed (1969)

Field growth response of cotton ( Gossypium hirsutum L.) to chilling during germination was investigated by laboratory application of controlled dosages of cold, followed by germination in sterile soil and subsequent field culture to maturity. Chilling during germination reduced plant height, delayed fruiting, and reduced fiber quality in a direct relation to the length of exposure to cold.
Silver-based nanomaterials: A critical review on factors affecting water disinfection performance and silver release (2020)

Water safety is one of the major environmental issues. Drawbacks of the conventional disinfection methods necessitate alternative, novel, low-cost, safe and highly efficient disinfection methods. With the advancements in nanotechnology, excellent antibacterial properties of nanosilver started to be used extensively in disinfecting medical devices, food packaging, clothing-fabrics and water-air disinfection. Recent studies showed that nanosilver-based materials used as disinfectants are highly promising to replace or to enhance the effectiveness of the conventional water disinfection methods. This is because, nanosilver-based materials do not generate carcinogenic disinfection-by-products (DBPs), require less energy, have no clogging problem, and achieve high removal efficiencies. In order to develop and improve disinfection methods with nanosilver-based materials, it is fundamental to understand the factors affecting their water disinfection performance. This review article, for the first time, focuses on the major factors affecting the water disinfection performance of nanosilver-based materials such as microbial culture, flow rate, silver concentration and water characteristics. The factors affecting silver release were also discussed. Understanding of these factors would certainly improve the development of nanosilver-based technologies. The compilation of the results presented herein will be helpful in guiding researchers who aim to work on this subject.
A Comparison of Cleavable and Noncleavable Hydrazinopyridine Linkers for the99mTc Labeling of Fab‘ Monoclonal Antibody Fragments (1996)

The design and synthesis of hydrazinopyridine bifunctional chelating agents (BCA's) featuring amide, ester, and disulfide groups are described. The BCA's site-specifically react with the free thiol groups of the tumor-specific monoclonal antibody fragment C46.3 using a one-pot in situ reduction and conjugation procedure from the F(ab')2 to give Fab'-linker conjugates. Molar substitution ratios (MSR's) of the hydrazinopyridine conjugates were comparable to the theoretical (maximum) number of thiols per fragment determined by free hydrazine and residual thiol assays. The series of C46.3 Fab'-linker conjugates were 99mTc-labeled in greater than 95% radiochemical purity by incubation with 99mTc-tricine for 1 h at room temperature. In order to evaluate the conjugates for radiopharmaceutical applications, the tumor localization and biodistribution properties of the radiolabeled Fab'-linker conjugates, compared to the direct labeled fragment, were tested in nude mice bearing LS174T xenografts. Depending upon the structure of the linker connecting the radiolabeled hydrazinopyridine group to the antibody fragment, we observed a variation in kidney uptake and whole-body clearance. Diester- and monoester-linked conjugates exhibited lower kidney uptake and faster whole-body clearance than the corresponding linker containing amide groups. This result may be interpreted as evidence for rapid metabolism of ester compared to amide groups in the kidney following uptake. At 24-h postinjection, the monoester-linked conjugate 99mTc-C46.3 Fab'-BA displayed the highest tumor: blood ratio (16.2) compared to the directly labeled conjugate (6.6) and is therefore a potential clinical candidate for imaging breast and ovarian cancer.
Continuity of Monolayer-Bilayer Junctions for Localization of Lipid Raft Microdomains in Model Membranes (2016)

We show that the selective localization of cholesterol-rich domains and associated ganglioside receptors prefer to occur in the monolayer across continuous monolayer-bilayer junctions (MBJs) in supported lipid membranes. For the MBJs, glass substrates were patterned with poly(dimethylsiloxane) (PDMS) oligomers by thermally-assisted contact printing, leaving behind 3 nm-thick PDMS patterns. The hydrophobicity of the transferred PDMS patterns was precisely tuned by the stamping temperature. Lipid monolayers were formed on the PDMS patterned surface while lipid bilayers were on the bare glass surface. Due to the continuity of the lipid membranes over the MBJs, essentially free diffusion of lipids was allowed between the monolayer on the PDMS surface and the upper leaflet of the bilayer on the glass substrate. The preferential localization of sphingomyelin, ganglioside GM1 and cholesterol in the monolayer region enabled to develop raft microdomains through coarsening of nanorafts. Our methodology provides a simple and effective scheme of non-disruptive manipulation of the chemical landscape associated with lipid phase separations, which leads to more sophisticated applications in biosensors and as cell culture substrates.