gebhart/patrepeval huggingface dataset:
Importance of Selected Inhaler Characteristics and Acceptance of a New Breath-Actuated Powder Inhalation Device (1997)

The degree of patient comfort and satisfaction with an inhaler can have an important effect on compliance with asthma treatment and, hence, therapeutic success. The objective of this study was to assess, from the patient's perspective, the importance of various inhaler characteristics and then evaluate patient satisfaction with a new breath-actuated powder inhaler (Diskhaler) based on those characteristics. Self-administered patient satisfaction questionnaires were completed as part of a randomized, double-blind, placebo-controlled study of fluticasone propionate powder in the treatment of asthma. At baseline, patients rated the importance of five inhaler characteristics (convenient to carry, durability, easy to load, easy to hold and operate, and easy to clean). Following exposure to the Diskhaler over a period of 8 weeks, patients rated the inhaler on those same characteristics. They also rated their comfort using the inhaler and their overall satisfaction with the inhaler. Data were available from 274 patients, the majority of whom expressed a high or very high level of satisfaction with the Diskhaler on each of the five characteristics. These ratings were congruent with their ratings of the importance of those same characteristics; 80-90% rated "convenient to carry," "durability," "easy to load," and "easy to hold and operate" as important or very important characteristics for an inhaler, while "easy to clean" was considered somewhat less important, with 63% rating this characteristic as important or very important. Following the initial exposure to the Diskhaler, 67% of patients were comfortable or very comfortable with the inhaler; that percentage increased to 79% after 8 weeks of use. Following 2 and 8 weeks of use, 61 and 62%, respectively, were satisfied or very satisfied with the Diskhaler. In general, satisfaction ratings were not affected by treatment, indicating that patients were evaluating only the inhaler and not the efficacy of the study drug they received. This study helped to identify which selected inhaler characteristics are most important to patients with asthma. The Diskhaler inhaler performed well on those characteristics deemed important to the patients. From their first exposure to the Diskhaler, patients were comfortable using the device, and this overall acceptance of the inhaler was maintained throughout the study.
The guinea-pig enterocyte as a model to investigate glycoprotein biosynthesis: isolation of microvillus and rough-endoplasmic-reticulum membranes (1982)

Conference Article| October 01 1982 The guinea-pig enterocyte as a model to investigate glycoprotein biosynthesis: isolation of microvillus and rough-endoplasmic-reticulum membranes JOANNE C. WALL; JOANNE C. WALL *Department of Surgery, St. George's Hospital Medical School, London SW17 0RE, U.K. Search for other works by this author on: This Site PubMed Google Scholar JOHN GRAHAM; JOHN GRAHAM †Department of Biochemistry, St. George's Hospital Medical School, London SW17 0RE, U.K. Search for other works by this author on: This Site PubMed Google Scholar JOHN HERMON-TAYLOR; JOHN HERMON-TAYLOR *Department of Surgery, St. George's Hospital Medical School, London SW17 0RE, U.K. Search for other works by this author on: This Site PubMed Google Scholar DAVID S. BAILEY DAVID S. BAILEY *Department of Surgery, St. George's Hospital Medical School, London SW17 0RE, U.K. Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1982) 10 (5): 355–356. https://doi.org/10.1042/bst0100355 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Cite Icon Cite Get Permissions Citation JOANNE C. WALL, JOHN GRAHAM, JOHN HERMON-TAYLOR, DAVID S. BAILEY; The guinea-pig enterocyte as a model to investigate glycoprotein biosynthesis: isolation of microvillus and rough-endoplasmic-reticulum membranes. Biochem Soc Trans 1 October 1982; 10 (5): 355–356. doi: https://doi.org/10.1042/bst0100355 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1982 Biochemical Society1982 Article PDF first page preview Close Modal You do not currently have access to this content.
Experimental infection with Besnoitia besnoiti tachyzoites in calves and young bulls (2017)

Trabajo presentado al: 4th International Meeting on Apicomplexa in Farm
Animals. (11-14 October 2017 - Madrid, Spain).
The magnitude and predictors of therapy abandonment in pediatric central nervous system tumors in low‐ and middle‐income countries: Systematic review and meta‐analysis (2019)

In LMICs, ARs are highest in lower-MICs. However, the paucity of published data limits further evaluation. Given the increasing burden of pediatric CNS tumors in LMIC, addressing deficits in abandonment reporting is critical. Consistent reporting is needed for developing interventions to improve outcomes.
Mapping and Tracking (2009)

This article presents the implementation of decentralized data fusion (DDF) and cooperative control algorithms on an unmanned aerial system (UAS).We conduct a number of demonstrations with a pair of unmanned aerial vehicles (UAVs) performing an information-gathering mission, and we show that significant benefits can be achieved by enabling cooperation through the sharing of information between members of the team. The objective is to utilize the UAV team to estimate the position and velocity of a number of ground-based features. The UAVs are given some prior knowledge of the feature states and are required to gather further information above a predefined threshold. This situation models a scenario where initial information is made available from an external source (e.g., a high-flying UAV or satellite imagery), which then prompts the start of the feature-localizationmission.
Statistical Analysis of Creep Crack Growth Data in Type 316LN Stainless Steel (2005)

The creep crack growth rate (CCGR) behavior of type 316LN stainless steel (SS) is analyzed statistically.The CCGR data is obtained from the CCGR tests, which are conducted with various applied loads of 5500N to 7000N at 600 o C. The CCGR is characterized as a function of the C * fracture parameter of da/dt = B[C * ] q .In order to logically obtain the B and q values, the three methods of the least square fitting method (LSFM), a mean value method (MVM) and a probabilistic distribution method (PDM) are applied.All of the CCGR lines of the three methods are in good accord with the experimental data.The PDM is most useful in predicting the CCGR equation because the CCGR line locates at medium between the other two lines and can be treated with a probabilistic analysis.Both the B and q coefficients follow a lognormal distribution, even though the B values are located in a broad range.The probability variables, P (B, q) are discussed in a case of the standard deviation of 1.Fracture morphologies of the intergrannular crack with microvoids are examined to verify the creep crack.
Supplemental Materials for Stein Gold et al. A Phase 2b, Randomized Clinical Trial of Tapinarof Cream for the Treatment of Plaque Psoriasis: Secondary Efficacy and Patient-Reported Outcomes. J Am Acad Dermatol. 2020. (2020)

Mendeley Supplemental Tables and Figures for Stein Gold et al. A Phase 2b, Randomized Clinical Trial of Tapinarof Cream for the Treatment of Plaque Psoriasis: Secondary Efficacy and Patient-Reported Outcomes. J Am Acad Dermatol. 2020.
Self-pumped four-wave mixing using backward and forward Brillouin scattering (1989)

Investigations of self-pumped phase conjugation using Brillouin-enhanced four-wave mixing in TiCl4 at 1 μm are presented. We have (1) observed both forward and backward Brillouin scattering into the optical cavity used for self-pumped phase conjugation during a single pump laser pulse and enhanced the forward-scattered component relative to the backward-scattered component by changing the angle of incidence of the pump beam, (2) demonstrated up to 80% coupling of pump radiation into cavity radiation, (3) examined quenching of the radiation in the optical cavity and eliminated both multiple Stokes orders from Brillouin scattering and Raman scattering as possible mechanisms, (4) observed mode beating in the cavity intensity profile coincident with the quenching, and (5) studied ring-resonator geometries, demonstrating both forward and backward scattering, unidirectional oscillation, and bidirectional oscillation leading to a triple-shifted phase conjugate.
The Microstructural Evolution and Swelling Behavior of Type 316 Stainless Steel Irradiated in HFIR (1990)

Solution annealed (SA) and 20% cold worked (CW) Type 316 (UNS S 31600) stainless steels were irradiated in the high flux isotope reactor (HFIR) to 55 dpa and to 3445 appm helium at 300 to 500°C. The irradiated specimens were examined by transmission electron microscopy (TEM) to evaluate microstructural evolution. At irradiation temperatures of 400°C and below, there was very little difference in the microstructural and swelling behavior between SA and CW material. A high concentration of fine bubbles was uniformly dispersed in the matrix. Swelling was very low (&amp;lt;0.4%). High concentrations of dislocation loops were observed. No precipitates were found at 300°C. A few precipitates were observed in the matrix and along the grain boundaries at 400°C. Large differences in swelling behavior and in the formation of precipitates appeared between 400 and 500°C. Low concentrations of large dislocation loops were observed in both materials at 500°C. The cavity size distributions were broad, but clearly bimodal. Swelling values in SA and CW were 2.3 and 0.7%, respectively. Many coarse precipitates were found in the matrix of SA, which were identified as M6C type phase enriched in nickel, iron, chromium, silicon, and molybdenum. The CW material developed fewer precipitates than the SA material at 500°C. Swelling behavior was compared in heat-to-heat variations of Type 316 stainless steel irradiated in HFIR. Significant swelling differences between heats are seen for irradiations in the temperature range of 500°C and above and at fluences beyond 30 dpa.
Isomerization of polyacetylene films of the Shirakawa type - spectroscopy and kinetics (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIsomerization of polyacetylene films of the Shirakawa type - spectroscopy and kineticsHarry W. Gibson, Samuel. Kaplan, Ralph A. Mosher, W. M. Prest, and Ronald J. WeagleyCite this: J. Am. Chem. Soc. 1986, 108, 22, 6843–6851Publication Date (Print):October 1, 1986Publication History Published online1 May 2002Published inissue 1 October 1986https://pubs.acs.org/doi/10.1021/ja00282a001https://doi.org/10.1021/ja00282a001research-articleACS PublicationsRequest reuse permissionsArticle Views149Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Multi-color and Multi-Material 3D Printing of Knee Joint models (2021)

The proposed anatomical models offer a diverse range of applications. These may be considered as an alternative to replacing cadaver specimens for medical training, pre-operative planning, research and education purposes, and predictive models validation. The soft tissue anatomy-mimicking materials are strong enough to withstand the stretching during the flexo-extension. The methodology reported for the design of the fiber-matrix structure might be considered as a start to develop new patterns and typologies that may mimic soft tissues.
Conversion of 1-methoxy substituted isochromenes into dimers of 2-benzopyrylium salts (1996)

Treatment of isochromenes 1 with AcOH or HCOOH followed by addition of water as well as heating of 1 produced dimers 2, 7 and 10.
Si no llegas a las estrellas, quédate con las nubes (1993)

El verano parece que ha sido este ano, para muchos, como un largo fin de semana en el que solo se han recargado levemente las pilas y se ha continuado con lo mismo que se hacia antes; sin apenas variacion, casi sin altibajos. En otras ocasiones, los meses de estio significaban una especie de olvido de lo anterior y un jalon para iniciar actividades nuevas. En los meses de junio y julio se hacia algo asi como una liquidacion por inventario y, despues de agosto, se iniciaba la nueva temporada. Este ano no ha sido asi.
Design of a Cylindrical Cavity Resonator for Measurements of Electrical Properties of Dielectric Materials (2010)

In microwave communications, the main aspects for affecting the dielectric losses in the materials are relating to the dielectric properties and the radiation frequencies. Normally, the different dielectric materials will lead to the different losses and reflections for microwave frequencies. To evaluate the dielectric properties from the different materials plays an essential role in the microwave engineering. There are many approaches can be used to measure the dielectric materials, e.g. capacitor methods, transmission line methods, cavity resonator methods, open cavity methods and so on. The cavity resonator method is one of the most popular ways for measuring the dielectric materials. In this thesis, some of the techniques will be reviewed, and the TM010 mode cylindrical cavity resonator with perturbation technique will be used for determining the dielectric properties. The design and measurements will be presented in both simulations and practice. With 1.2GHz cavity resonator, in the simulations, the dielectric permittivity for Teflon is measured as 2.09-0.0023i and 2.12-0.0116 in copper cavity and ferromagnetic cavity. Finally the sample is measured as 3.83-0.12i in practice.
Mobilizing the Powerless: Collective Protest Action of the Unemployed in the Interwar Period (2002)

This paper examines the origins and evolution of collective protest action, and of organized movements, of the unemployed in Britain and the USA in the interwar period. It addresses three interrelated issues in the study of social movements: the problems of collective action amongst a relatively powerless sector of society; the role of external agents in the processes of mobilization and organization; and the effects of organization on levels of militancy and mobilization. Examination of both cases confirms first, the importance of the mass nature of unemployment in fomenting initial protest action of the unemployed in the early 1920s and early 1930s; second, the critical role of external agents in developing and consolidating organizations of the unemployed; and third, that the allegedly deradicalizing effects of organization on the behaviour and objectives of poor people’s movements are exaggerated. However, sharp contrasts between the (more hostile) British and (more benign) American political contexts in the 1930s casts doubt on the ability of the so-called political opportunity structure to explain the emergence and evolution of collective protest action by
Laminin-111 Improves the Anabolic Response to Mechanical Load in Aged Skeletal Muscle (2020)

Anabolic resistance to a mechanical stimulus may contribute to the loss of skeletal muscle mass observed with age. In this study, young and aged mice were injected with saline or human LM-111 (1 mg/kg). One week later, the myotendinous junction of the gastrocnemius muscle was removed via myotenectomy (MTE), thus placing a chronic mechanical stimulus on the remaining plantaris muscle for 2 weeks. LM-111 increased α7B integrin protein expression and clustering of the α7B integrin near DAPI+ nuclei in aged muscle in response to MTE. LM-111 reduced CD11b+ immune cells, enhanced repair, and improved the growth response to loading in aged plantaris muscle. These results suggest that LM-111 may represent a novel therapeutic approach to prevent and/or treat sarcopenia.
Temporal trends in management and outcome of patients with acute coronary syndrome according to admission low-density lipoprotein cholesterol levels (2020)

Treatment of ACS patients has improved over the past decades regardless of LDL-C levels. This improvement was accompanied by lower mortality rates in ACS patients with LDL-C ≥130 mg/dl, but not in patients with LDL-C <130 mg/dl.
Microwave Sintering of Multilayer Integrated Passive Devices (2010)

Microwave sintering of multilayer capacitor/varistor‐based integrated passive devices (IPDs) has been investigated for the first time. The sintered samples were characterized for density, microstructure, composition, and electrical performance. It was found that IPDs with varistor/capacitor formulations could be microwave sintered to fully dense device components within 3 h of total cycle time, which is &lt;1/10th of the time required by conventional methods. Microwave sintering resulted in products with a finer grain structure and without delamination or significant interdiffusion between the ceramic/electrode and varistor/capacitor interfaces. The microwave method also completely eliminated the need for a separate binder burnt‐out step. The electrical properties of the microwave‐sintered samples were found to better or match those obtained by conventional, industrial processing. In general, the simplicity, rapidity, and superior product performance make the microwave technique an attractive sintering methodology for the processing of IPDs.
Accuracy considerations in using the PML ABC with FDFD Helmholtz equation computation (2000)

A careful analysis of discretization error in various implementations of Berenger's PML absorbing boundary condition for the FDFD method applied to the Helmholtz equation is presented. Analytic and numerical formulations indicate the clear superiority of specifying the material characteristics in terms of the coupled Ampere's and Faraday's laws first, and then combining the first-order differential equations a discrete Helmholtz-like difference equation. Copyright © 2000 John Wiley & Sons, Ltd.
[Treatment of pulmonary hypertension in COPD: is there hope for the better?]. (2005)

The aim of this study is to prove for a well tolerated medication (clinical and financial) a supplementary effect in improvement prognosis of patients with pulmonary hypertension secondary to COPD, already treated with classical pneumology drugs. Three pts. groups were selected: the first received only classical pneumology treatment, the second with supplementary therapy by IECA and Ca-blockers, the third with supplementary therapy with IECA and nebivolol; the follow-up protocol included clinical and paraclinical status (blood gases, spirometry, ECG, echocardiography, 6 minute walk test) over 3 months. Clinical and paraclinical evolution of the pts. in group 2 and group 3 was significantly better that in pts from group 1. We conclude that addition of IECA + Ca-blocker/IECA + nebivolol therapy at classical pneumology therapy result in a better evolution in pts. with pulmonary hypertension secondary to COPD.
A New Method To Characterize Fractured Reservoirs: Applications to Infill Drilling (1994)

ABSTRACT A new approach in fractured reservoir characterization that integrates geomechanics, geology, petrophysics and reservoir engineering is proposed and illustrated with an actual oil reservoir. This approach uses a generalized form of the curvature method to derive a model for fracture intensity and orientation for the Young Deep Unit (YDU). A reservoir inverse model was used to convert the fracture properties into effective petrogeological attributes. The inverse model uses simulated annealing and a black oil simulator to estimate fracture directional permeabilities and pore volume, reservoir wettability, and wellbore properties. The conditioned reservoir model that matches oil, gas, and water monthly rates, and reservoir pressure for a 151 month period, was used to construct an infill drilling criterion map to locate the best infill locations in the YDU.
The K/BxN Mouse Model of Inflammatory Arthritis (2007)

Mice expressing the KRN T cell receptor transgene and the MHC class II molecule A(g7) (K/BxN mice) develop severe inflammatory arthritis, and serum from these mice causes similar arthritis in a wide range of mouse strains, owing to pathogenic autoantibodies to glucose-6-phosphate isomerase (GPI). This model has been useful for the investigation of the development of autoimmunity (K/BxN transgenic mice) and particularly of the mechanisms by which anti-GPI autoantibodies induce joint-specific imflammation (serum transfer model). In this chaper, after a summary of findings from this model system, we describe detailed methods for the maintenance of a K/BxN colony, crossing of the relevant TCR and MHC genes to other strain backgrounds, evaluation of KRN transgenic T cells, measurement of anti-GPI antibodies, induction of arthritis by serum transfer, and clinical and histological evaluation of arthritis.
Discrimination of n‐3 Rich Oils by Gas Chromatography (2010)

Exploring the capabilities of instrumental techniques for discriminating n-3 rich oils derived from animals is a very important though much neglected area that was emphasized more than 100 years ago. In this study the potential of gas chromatography (GC) for discriminating full fatty acid methyl ester (FAME) profiles from fish (cod liver and salmon) and marine mammal (seal and whale) oils is evaluated by means of principal component analysis (PCA). The FAME profiles from plant oils such as rapeseed, linseed and soy oils and seven different brands of n-3 supplements are also used in the discrimination process. The results from the PCA plots can reliably distinguish between plant, n-3 supplements, fish and marine mammal oils. By removing the contribution of the n-3 supplements and plant oils it is possible to discriminate between types of fish and marine animal oils. GC offers a rapid, simple and convenient means of discriminating oils from different species, brands and grades.
Risk factors and rates of bone flap resorption in pediatric patients after decompressive craniectomy for traumatic brain injury (2013)

After decompressive craniectomy for pediatric TBI, half of the patients (50%) who underwent bone flap replacement experienced resorption. Multivariate analysis indicated young age (≤ 2.5 years), hydrocephalus, underlying contusion as opposed to a hemispheric acute subdural hematoma, and a comminuted skull fracture were all independent risk factors for bone flap resorption. Freezer time was not found to be associated with bone flap resorption.