gebhart/patrepeval huggingface dataset:
The physics of solid-state neutron detector materials and geometries (2010)

Detection of neutrons, at high total efficiency, with greater resolution in kinetic energy, time and/or real-space position, is fundamental to the advance of subfields within nuclear medicine, high-energy physics, non-proliferation of special nuclear materials, astrophysics, structural biology and chemistry, magnetism and nuclear energy. Clever indirect-conversion geometries, interaction/transport calculations and modern processing methods for silicon and gallium arsenide allow for the realization of moderate- to high-efficiency neutron detectors as a result of low defect concentrations, tuned reaction product ranges, enhanced effective omnidirectional cross sections and reduced electron-hole pair recombination from more physically abrupt and electronically engineered interfaces. Conversely, semiconductors with high neutron cross sections and unique transduction mechanisms capable of achieving very high total efficiency are gaining greater recognition despite the relative immaturity of their growth, lithographic processing and electronic structure understanding. This review focuses on advances and challenges in charged-particle-based device geometries, materials and associated mechanisms for direct and indirect transduction of thermal to fast neutrons within the context of application. Calorimetry- and radioluminescence-based intermediate processes in the solid state are not included.
Bio-functionalized Pt nanoparticles based electrochemical impedance immunosensor for human cardiac myoglobin (2014)

We report the covalent immobilization of three-dimensional carboxyl-functionalized Pt(MPA) nanoparticles with myoglobin protein antibody by carbodiimide coupling reaction deposited onto an indium-tin-oxide-coated glass plate for the construction of a bioelectrode.
Deep Learning Based Test Compression Analyzer (2019)

With the increase in design complexity and test data volume, compressed tests together with on-chip test decompression hardware such as Embedded Deterministic Test (EDTTM) are widely used in industry in order to reduce test cost. One of the challenges of such Design-for-Test (DFT) technology is to determine a set of optimal parameters such as the number of scan chains, scan channels, power budget, etc. such that it can reach the highest test coverage with a minimum amount of test data volume whilst satisfying various other constraints. To achieve the optimal compression configuration quickly, in this work deep learning technology based on Tensorflow is explored to estimate the test coverage and the data volume for a design when employing EDT under a given set of circuit parameters. Based on the estimated data, the optimal test architecture is also predicted, yielding a more efficient approach compared to the currently used trial-and-error methods. To demonstrate the advantages of our deep learning approach over the currently used utility, we present experimental data for eight industrial designs.
Drag of Micro-Particles by an Extended Nematic-Isotropic Interface (2004)

We studied the behaviour of polymer particles in a moving interface between the nematic(N)and isotropic(I)phases of a nematic liquid crystal(LC). We showed that theNI-interface is extended(E)and has a layeredN-I-Nstructure in the vertical cross-section of the sample; the wedge of the isotropic phase is bounded by the nematic phase, which is limited by the cell substrates. The minimum of the cell free energy defines the position of particles in the interface region. We find that the preferable position of the particle is at the vertex of the wedge formed by the isotropic phase. The particles are captured by the vertex line and follow the interface when it moves.
Cutting Edge: Limiting Amounts of IL-7 Do Not Control Contraction of CD4+ T Cell Responses (2007)

During the acute T cell response most effector T cells die while some survive and become memory T cells. Selective expression of CD127 (IL-7Ralpha) on effector T cells has been proposed to engender their survival into the memory pool. We assessed the role of IL-7 in effector T cell survival using MHC class II tetramers to track a CD4+ T cell response following infection with a recombinant vaccinia virus (rVV-2W1S). Exogenous IL-7 prevented the contraction of the 2W1S-specific CD4+ T cell response after rVV-2W1S infection. IL-7 increased proliferation of, and Bcl-2 expression within, 2W1S-specific T cells; the latter was required for IL-7-driven prevention of contraction. Conversely, in vivo neutralization of IL-7 or Bcl-2 did not exacerbate the contraction of 2W1S-specific CD4+ T cells. These data suggest that IL-7 administration may enhance the survival of effector T cells but that IL-7 is not the limiting factor during normal contraction of the response.
Switching to Nevirapine Decreases Insulin Levels but Does Not Improve Subcutaneous Adipocyte Apoptosis in Patients with Highly Active Antiretroviral Therapy–Associated Lipodystrophy (2001)

Subcutaneous adipocyte apoptosis occurs in lipotrophic areas of patients with highly active antiretroviral therapy (HAART)-associated lipodystrophy. Fourteen patients with HAART-associated lipodystrophy had 2 subcutaneous biopsies for evidence of adipocyte apoptosis, the second after a randomized change to nevirapine (n=8) or after remaining on a regimen of indinavir-based HAART (n=6). Apoptosis was assessed by the terminal deoxynucleotidyl transferase dUTP-digoxigenin nick end-labeling method. Patients who were switched to nevirapine had a significant decrease in insulinemia and a significant increase in the glucose:insulin ratio. Overall, subcutaneous adipocyte apoptosis increased in 3 patients who were switched to nevirapine and in 3 who continued to receive indinavir but decreased in 2 patients switched to nevirapine and another 2 who continued to receive indinavir. Subcutaneous adipocyte apoptosis continues to occur in lipotrophic areas of patients with HAART-associated lipodystrophy despite switching from indinavir to nevirapine, suggesting that such a strategy will be useless for reversal of lipoatrophy.
Purification of Recombinant Proteins with High Isoelectric Points (2004)

The use of recombinant antigens is essential for the construction of robust and sensitive diagnostic assays. A critical step in the preparation of recombinant antigens is protein purification. Purification problems may be very different for related structural proteins expressed in the same host or for the same protein expressed in different hosts, because the biochemical characteristics of a recombinant protein, expressed in a heterologous system, are unique. In this chapter we make a brief introduction to protein purification procedures and we present a quick purification process suitable for the isolation of recombinant protein having high isoelectric points encoding non-conformational epitopes.
Synthesis and Anti-Bacterial Activities of a Bis-Chalcone Derived from Thiophene and Its Bis-Cyclized Products (2011)

A chalcone was prepared by the reaction of terephthalaldehyde with 3-acetyl-2,5-dimethylthiophene. Treatment of this chalcone with thiosemicarbazide/phenyl hydrazine/guanidine hydrochloride/thiourea afforded the corresponding pyrazoline, pyrazole, and pyrimidine in good yields. All the new compounds have been characterized by IR, 1H-NMR, 13C-NMR, GC-MS and elemental analyses. The anti-bacterial activity of these compounds were first tested in vitro by the disk diffusion assay against two gram-positive and two gram-negative bacteria, and then the minimum inhibitory concentration (MIC) was determined with the reference of standard drug chloramphenicol. The results showed that the pyrazoline derivative is better at inhibiting growth of both types of bacteria (gram-positive and gram-negative) compared to chloramphenicol.
Accumulation of Glucose 6-Phosphate or Fructose 6-Phosphate Is Responsible for Destabilization of Glucose Transporter mRNA inEscherichia coli (2003)

Previously we found that a mutation in either pgi or pfkA, encoding phosphoglucose isomerase or phosphofructokinase A, respectively, facilitates degradation of the ptsG mRNA in an RNase E-dependent manner in Escherichia coli (1). In this study, we examined the effects of a series of glycolytic genes on the degradation of ptsG mRNA and how the mutations destabilize the ptsG mRNA. The conditional lethal mutation ts8 in fda, encoding fructose-1,6-P(2) aldolase just downstream of pfkA in the glycolytic pathway, caused the destabilization of ptsG mRNA at the nonpermissive temperature. Mutations in any other gene did not destabilize the ptsG mRNA; rather, they reduced the ptsG transcription mainly by affecting the cAMP level. The rapid degradation of ptsG mRNA in mutant strains was completely dependent upon the presence of glucose or any one of its compounds, which enter the Embden-Meyerhof glycolytic pathway before the block points. A significant increase in the intracellular glucose-6-P level was observed in the presence of glucose in the pgi strain. An overexpression of glucose-6-phosphate dehydrogenase eliminated both the accumulation and the degradation of ptsG mRNA in the pgi strain. In addition, accumulation of fructose-6-P led to the rapid degradation of ptsG mRNA in a pgi pfkA mutant strain lacking glucose-6-P. We conclude that the RNase E-dependent destabilization of ptsG mRNA occurs in response to accumulation of glucose-6-P or fructose-6-P.
Conduction Processes in Thick Film Resistors. Part II (1976)

The structures of three families of thick film resistors have been investigated by scanning electron microscopy and electron probe micro‐analysis. The two principal components of the resistive glazes, that is the conducting pigment and the glassy binder, have been identified in each case. The pigments were found to be simple or ternary oxides of the Pt transition metal group and Pd/PdO/Ag alloys. The glassy binders were based on lead borosilicate glasses. A model for the electronic conduction processes through the glass and pigments is proposed on the basis of the observed physical structures, the measured electrical properties of resistors and the properties of the component resistor materials. Part I of the total paper is concerned with identifying the phases in various thick film resistors and part II considers the conduction processes that are applicable.
Economists as Worldly Philosophers (2011)

While leading figures in the early history of economics conceived of it as inseparable from philosophy and other humanities, there has been movement, especially in recent decades, towards its becoming an essentially technical field with narrowly specialized areas of inquiry. Certainly, specialization has allowed for great progress in economic science. However, recent events surrounding the financial crisis support the arguments of some that economics needs to develop forums for interdisciplinary interaction and to aspire to broader vision.
A Vehicle-following Model Based on Drivers Different Sensitive to Vehicle Speed and Vehicle's Spacing (2009)

Through researching at the traditional linear model of car-following, the paper have found it sensitivity is a fixed value, but in the actual process of driving a vehicle, Sensitivity of driver changes with stimulation. This paper set up a new vehicle-following model taking into account the different sensitivity. Through simulation analysis, results show that the new model be able to clarify the car-following status better, and superior to the traditional model.
Plasmonic Paper Microneedle Patch for On-Patch Detection of Molecules in Dermal Interstitial Fluid (2019)

Minimally invasive devices to detect molecules in dermal interstitial fluid (ISF) are desirable for point-of-care diagnostic and monitoring applications. In this study, we developed a microneedle (MN) patch that collects ISF for on-patch biomarker analysis by surface-enhanced Raman scattering (SERS). The micrometer-scale MNs create micropores in the skin surface, through which microliter quantities of ISF are collected onto plasmonic paper on the patch backing. The plasmonic paper was prepared by immobilizing poly(styrenesulfonate) (PSS) coated gold nanorods (AuNRs) on a thin strip of filter paper using plasmonic calligraphy. Negatively charged PSS was used to bind positively charged rhodamine 6G (R6G), which served as a model compound, and thereby localize R6G on AuNR surface. R6G bound on the AuNR surface was detected and quantified by acquiring SERS spectra from the plasmonic paper MN patch. This approach was used to measure pharmacokinetic profiles of R6G in ISF and serum from rats in vivo. This proof-of-concept study indicates that a plasmonic paper MN patch has the potential to enable on-patch measurement of molecules in ISF for research and future medical applications.
Excess volumes of 1,1,2,2-tetrachloroethane + ketone (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTExcess volumes of 1,1,2,2-tetrachloroethane + ketoneNettem V. Choudary, Jyoti C. Mouli, A. Krishnaiah, and P. R. NaiduCite this: J. Chem. Eng. Data 1984, 29, 2, 161–163Publication Date (Print):April 1, 1984Publication History Published online1 May 2002Published inissue 1 April 1984https://pubs.acs.org/doi/10.1021/je00036a018https://doi.org/10.1021/je00036a018research-articleACS PublicationsRequest reuse permissionsArticle Views27Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
DJ-1 protein and Apolipoprotein E are new targets for LVVYPW in diabetic rat brain. Dopaminergic system in the striatum of healthy rats is also target for hemorphin (2014)

Author: Barkhudaryan, N. et al.; Genre: Journal Article; Issued: 2014; Title: DJ-1 protein and Apolipoprotein E are new targets for LVVYPW in diabetic rat brain. Dopaminergic system in the striatum of healthy rats is also target for hemorphin
Optical generation of logarithmic harmonic filters for projection invariant pattern recognition (1992)

Invariant pattern recognition systems are based on spatial filters that are in most cases computer-generated holograms. Logarithmic harmonics were suggested to be used in implementations that perform projection invariant pattern recognition. A novel approach for optical generation of logarithmic harmonic matched filters of a universal nature, usable for arbitrary input patterns, is presented, followed by some initial experimental results.
Predictive Pulse-Pattern Current Modulation Scheme for Harmonic Reduction in Three-Phase Multidrive Systems (2016)

The majority of the industrial motor drive systems are equipped with the conventional line-commutated front-end rectifiers and being one of the main sources of harmonics in the power line. While a parallel combination of these drive units elevates current quality issues, a proper arrangement of them can lead to the cancellation of specific harmonics. This paper proposes a new cost-effective harmonic mitigation solution for multidrive systems using a predictive pulse pattern current modulation control strategy. The proposed technique applies suitable interaction among parallel drive units at the rectification stage to synthesize sinusoidal input currents. The input voltage sensing is avoided in order to minimize the number of required sensors, and the grid synchronization also has been implemented based on a common phase-locked loop (PLL) using the dc-link capacitor voltage ripple. Experimental results validate the effectiveness of the proposed strategy.
NRD-Guide Passive Components and Devices for Millimeter Wave Wireless Applications (2007)

Owing to simple structure, low cost and high performance, NRD-guide millimeter wave circuits have attracted much attention in recent years. In this paper, a variety of NRD-guide passive components are reviewed with emphasis on design techniques and performance estimation in the 60 GHz frequency band where the license-free advantage is available. The passive components to be discussed here include compact bends, wideband hybrid couplers, practical three-port junctions, versatile E-plane filters, and effective feeding structures for lens antennas. Some of them are employed to construct millimeter wave transceivers. Eye patterns observed at 1.5 Gbps confirm the potential ability of the fabricated NRD-guide transceivers for high bit-rate, wireless applications.
Evaluation of Nanoparticle Uptake in Tumors in Real Time Using Intravital Imaging (2011)

Current technologies for tumor imaging, such as ultrasound, MRI, PET and CT, are unable to yield high-resolution images for the assessment of nanoparticle uptake in tumors at the microscopic level1,2,3, highlighting the utility of a suitable xenograft model in which to perform detailed uptake analyses. Here, we use high-resolution intravital imaging to evaluate nanoparticle uptake in human tumor xenografts in a modified, shell-less chicken embryo model. The chicken embryo model is particularly well-suited for these in vivo analyses because it supports the growth of human tumors, is relatively inexpensive and does not require anesthetization or surgery 4,5. Tumor cells form fully vascularized xenografts within 7 days when implanted into the chorioallantoic membrane (CAM) 6. The resulting tumors are visualized by non-invasive real-time, high-resolution imaging that can be maintained for up to 72 hours with little impact on either the host or tumor systems. Nanoparticles with a wide range of sizes and formulations administered distal to the tumor can be visualized and quantified as they flow through the bloodstream, extravasate from leaky tumor vasculature, and accumulate at the tumor site. We describe here the analysis of nanoparticles derived from Cowpea mosaic virus (CPMV) decorated with near-infrared fluorescent dyes and/or polyethylene glycol polymers (PEG) 7, 8, 9,10,11. Upon intravenous administration, these viral nanoparticles are rapidly internalized by endothelial cells, resulting in global labeling of the vasculature both outside and within the tumor7,12. PEGylation of the viral nanoparticles increases their plasma half-life, extends their time in the circulation, and ultimately enhances their accumulation in tumors via the enhanced permeability and retention (EPR) effect 7, 10,11. The rate and extent of accumulation of nanoparticles in a tumor is measured over time using image analysis software. This technique provides a method to both visualize and quantify nanoparticle dynamics in human tumors.
Interfacial Engineering of Carbon Nanofiber–Graphene–Carbon Nanofiber Heterojunctions in Flexible Lightweight Electromagnetic Shielding Networks (2014)

Lightweight carbon materials of effective electromagnetic interference (EMI) shielding have attracted increasing interest because of rapid development of smart communication devices. To meet the requirement in portable electronic devices, flexible shielding materials with ultrathin characteristic have been pursued for this purpose. In this work, we demonstrated a facile strategy for scalable fabrication of flexible all-carbon networks, where the insulting polymeric frames and interfaces have been well eliminated. Microscopically, a novel carbon nanofiber-graphene nanosheet-carbon nanofiber (CNF-GN-CNF) heterojunction, which plays the dominant role as the interfacial modifier, has been observed in the as-fabricated networks. With the presence of CNF-GN-CNF heterojunctions, the all-carbon networks exhibit much increased electrical properties, resulting in the great enhancement of EMI shielding performance. The related mechanism for engineering the CNF interfaces based on the CNF-GN-CNF heterojunctions has been discussed. Implication of the results suggests that the lightweight all-carbon networks, whose thickness and density are much smaller than other graphene/polymer composites, present more promising potential as thin shielding materials in flexible portable electronics.
Catch-up Growth in Severe Juvenile Hypothyroidism: Treatment with a GnRH Analog (2004)

Anecdotal reports suggest that the addition of a gonadotropin releasing hormone (GnRH) analog (GnRHa) in addition to L-thyroxine (LT4) replacement may increase adult stature in children with severe longstanding hypothyroidism by prolonging the pubertal growth period. This retrospective chart review compares the height outcome and body mass index in 33 children (21 treated with LT4 alone and 12 treated with LT4 + GnRHa) with severe longstanding hypothyroidism and bone age delay. Seventeen controls and six GnRHa-treated patients were followed to adult height (BA >14 yr [F]/16 yr [M] and/or growth velocity < 2 cm/yr). At diagnosis, GnRHa-treated patients were 1) older and shorter for chronological age, and 2) more advanced in puberty and bone age. Despite these differences, at adult height, both groups had similar improvements in height Z scores, similar height deficits, and comparable adult heights. Changes in BMI Z score were similar for both groups. Our study suggests that the addition of GnRHa to LT4 may improve interval growth without imposing a risk of obesity in children with longstanding severe hypothyroidism.