gebhart/patrepeval huggingface dataset:
Ink-jet printing of In2O3 /ZnO 2D-structures from solution (2011)

International audience
Implementation and performance evaluation of Locust (2002)

Locust is a distributed shared virtual memory system that exploits compile-time data dependency information to address the issues of false sharing, cache coherence overhead, and affinity process scheduling. The paper reports the results and their analysis of a comprehensive performance evaluation study of the first Locust prototype, which is implemented on a 12-node Pentium cluster running FreeBSD and has been fully operational for a year. The results show that for the set of regular programs tested, the performance of Locust is within 1-8% of that of the message passing system implemented on the same hardware/software platform. The main performance gain of Locust as compared to existing weak cache consistency models mainly comes from the elimination of unnecessary synchronizations using the generational cache coherence protocol, and the function-shipping approach of implementing synchronization operations.
Development and properties of fructose 1,6-bisphosphatase in the endosperm of castor-bean seedlings (1976)

1. The activity of fructose 1,6-bisphosphatase (EC 3.1.3.11) in the fatty endosperm of castor bean (Ricinus communis) increases 25-fold during germination and then declines. The developmental pattern follows that of catalase, a marker enzyme for gluconeogenesis in this tissue. 2. The enzyme at its peak of development was partially purified, and its properties were studied. It has an optimal activity at neutral pH (7.0-8.0). The apparent Km value for fructose 1,6-bisphosphate is 3.8 X 10(-5) M. The activity is inhibited by AMP allosterically with an apparent Ki value of 2.2 X 10(-4) M. The enzyme hydrolyses fructose 1,6-bisphosphate and not ribulose 1,5-bisphosphate or sedoehptulose 1,7-bisphosphate. 3. Treatment of the partially purified enzyme with acid leads to an 80% decrease in activity. The remaining activity is insensitive to AMP and has optimal activity at pH 6.7 and a high apparent Km value (2.5 X 10(-4) M) for fructose 1.6-bisphosphate. Enzyme extracted from the tissue with water instead of buffer has a similar modification. The effect of acid explains the discrepancies between this report and previous ones on the properties of the enzyme in this tissue. 4. The storage tissues of various fatty seedlings all contain a 'neutral' fructose 1,6-bisphosphatase. The activities of the enzyme from some of the tissues are inhibited by AMP. 5. The properties of the enzyme in fatty seedlings and in green leaves are discussed in comparison with that in animal tissues.
Ligament Reconstruction and Calcaneal Osteotomy for Osteoarthritis of the Ankle (2009)

Calcaneal osteotomy with ligament reconstruction can be considered for treatment of the early stages of osteoarthritis of the ankle.
Metric-Based Data Mining Model for Genealogical Record Linkage (2007)

Genealogical Record Linkage (GRL) is the process of determining whether two pedigrees refer to the same base individual. Unlike other record linkage problems, GRL datasets are extremely sparse and have several multi-valued attributes. In this paper, we describe a metric-based, data mining approach to GRL, and report on its successful application to a large post-blocking, standardized database.
Improved Charge Pump with Reduced Reverse Current (2012)

A highly efficient charge pump that minimizes the reverse charge sharing current (in short, reverse current) is proposed. The charge pump employs auxiliary capacitors and diode-connected MOSFET along with an early clock to drive the charge transfer switches; this new method provides better isolation between stages. As a result, the amount of reverse current is reduced greatly and the clock driver can be designed with reduced transition slope. As a proof of the concept, a 1.1V-to-9.8 V charge pump was designed in a 0.35 μm 18 V CMOS technology. The proposed architecture shows 1.6 V ~ 3.5 V higher output voltage compared with the previously reported architecture.
Proteases Underground: Analysis of the Maize Root Apoplast Identifies Organ Specific Papain-Like Cysteine Protease Activity (2019)

Plant proteases are key regulators of plant cell processes such as seed development, immune responses, senescence and programmed cell death (PCD). Apoplastic papain-like cysteine proteases (PL) are hubs in plant-microbe interactions and play an important role during abiotic stresses. The apoplast is a crucial interface for the interaction between plant and microbes. So far, apoplastic maize PL and their function have been mostly described for aerial parts. In this study, we focused on apoplastic PLCPs in the roots of maize plants. We have analyzed the phylogeny of maize PLCPs and investigated their protein abundance after salicylic acid (SA) treatment. Using activity-based protein profiling (ABPP) we have identified a novel root-specific PLCP belonging to the RD21-like subfamily, as well as three SA activated PLCPs. The root specific PLCP CP1C shares sequence and structural similarities to known CP1-like proteases. Biochemical analysis of recombinant CP1C revealed different substrate specificities and inhibitor affinities compared to the related proteases. This study characterized a root-specific PLCP and identifies differences between the SA-dependent activation of PLCPs in roots and leaves.
Mutual-information based rate-adaptation for Multi-User TH-IR-UWB coded system (2011)

In this paper we present a coding rate adaptation technique for a Time-Hopping Impulse-Radio Ultra-Wide Band (TH-IR-UWB) system assuming that the Multi-User Interference (MUI) is modeled as an additive interference noise following a Generalized Gaussian Distribution (GGD). The shape parameter induced by the GGD model is in general time-variant since it strongly depends on the essential UWB system parameters and the received signal power of the active users. In this paper, we show that the performance of a TH-IR-UWB LDPC coded system is quite independent of the GGD shape parameter when we consider the mutual information between the soft input to the decoder and the transmitted sequence, especially for medium to high-rate regimes. This allows to derive a simple and efficient link adaptation scheme based on a rate-compatible protograph-based LDPC code. Simulated results are provided to evaluate the performance of the described coding rate adaptation algorithm for a TH-IR-UWB multi-user system.
Evaluating the Accuracy of Continuous Glucose-Monitoring Sensors (2004)

Traditional self-monitoring of BG device evaluation methods fail to capture the important temporal characteristics of the continuous glucose-monitoring process. CG-EGA addresses this problem, thus providing a comprehensive assessment of sensor accuracy that appears to be a useful adjunct to other CGS performance measures.
Testability analysis and insertion for RTL circuits based on pseudorandom BIST (2002)

A testability analysis technique for built-in self-test (BIST) at the system level is presented. While based on previous approaches, the model has several significant new features, including an iterative technique for modeling indirect feedback and an extension to the circular BIST methodology. Additionally, a new preprocessing transformation enables the correct modeling of word-level correlation. Examples validate the model, and demonstrate its applicability to test point insertion.
Power-efficient method for IM-DD optical transmission of multiple OFDM signals (2015)

We propose a power-efficient method for transmitting multiple frequency-division multiplexed (FDM) orthogonal frequency-division multiplexing (OFDM) signals in intensity-modulation direct-detection (IM-DD) optical systems. This method is based on quadratic soft clipping in combination with odd-only channel mapping. We show, both analytically and experimentally, that the proposed approach is capable of improving the power efficiency by about 3 dB as compared to conventional FDM OFDM signals under practical bias conditions, making it a viable solution in applications such as optical fiber-wireless integrated systems where both IM-DD optical transmission and OFDM signaling are important.
Kuwait Oil Company Employs a Systematic Approach to Ensure Successful Underbalanced Drilling Project: A Case Study (2008)

Abstract Kuwait Oil Company (KOC) is considering adapting new technologies to ensure that strategic resources are optimally explored, developed and produced during the life cycle of their oil and gas fields. Among the various options available to achieve these objectives, Under-balanced Drilling (UBD) technology is considered to be one of the most effective methods when it is effectively applied in conjunction with horizontal and/or Multi-lateral well drilling and completion techniques Accordingly, KOC decided to pioneer the introduction of this new technology by employing a systematic scientific approach to screen the Mauddud reservoir in the Greater Burgan field for under-balanced drilling candidacy, in order to ensure a successful implementation of the pilot project. The screening process incorporated reservoir, production, drilling, Geology &amp; Geophysics and operational data with risk analysis incorporated into a rigorous expert system aimed at maximizing the value of any UBD operation. The screening process was performed in two phases; a high level low resolution screening and in depth high resolution analysis. Phase I comprised of:Evaluating and ranking the Mauddud reservoir with respect to its risked probability of being successfully exploited with horizontal underbalanced drilling and completion techniques as opposed to conventional methods.Comparing candidate reservoirs against global database of analogues proven to be suitable with UBD. Phase II comprised of:Quantifying drilling-induced damage and determining the impact on the productivity on the Mauddud reservoir.Comparing under-balanced and overbalanced costs, production rates, projected revenues and Net Present Value (NPV). This paper describes the expert system methodology used in the screening process and provides a discussion of the results obtained. The Phase II study findings provided KOC with detailed damage analysis, production forecast and economic benefits that under-balanced drilling could offer as compared to conventional drilling &amp; completion technologies. The UBD Screening Process This paper investigates the reservoir suitability of underbalanced drilling using an Expert System screening process that was developed in conjunction with leading industry consultants to increase success in candidate selection and to evaluate the benefits of underbalanced drilling over traditional drilling and completion technology in terms of reservoir performance. The screening process began by taking basic information for the Mauddud reservoir and processing the information through the expert system phase I software. This software rates the candidacy of the reservoir to help determine the likelihood of achieving success with underbalanced compared to overbalanced drilling and completion techniques. All data input was reviewed for completeness and consistency.
Simvastatin Induces Apoptosis and Suppresses Insulin-Like Growth Factor 1 Receptor in Bile Duct Cancer Cells (2015)

Simvastatin induces apoptosis in bile duct cancer cells, which suggests that it could be an antineoplastic agent for bile duct cancer.
Identification and isolation of mycoplasmas by immunobinding. (1987)

This laboratory has developed an immunobinding assay (IBA) to identify and detect mycoplasmas in a variety of specimens. The specimen is inoculated in volumes of 10 microliters onto nitrocellulose (NC) paper, which is then blocked, fixed, and incubated at room temperature. Specific antimycoplasma polyclonal or monoclonal antibody is first added, followed by peroxidase-labeled antibody directed toward the first immunoglobulin. Alternately, antimycoplasma IgG can be purified and conjugated to horseradish peroxidase for use in a direct assay. Addition of a developing solution results in the formation of purple color when mycoplasmas are present. Titers of rabbit antimycoplasma antisera range from 1:1,000 to 1:30,000. This assay can detect approximately 1 x 10(4) colony-forming units (CFU). This IBA has been used routinely to identify mycoplasmal isolates from 132 infected cell cultures. In addition, the procedure successfully detected Mycoplasma pneumoniae in throat swabs from patients with respiratory illness within 2 h. Perfect correlation was obtained with the IBA and microbiological culture of throat swabs for M. orale, M. salivarium and M. pneumoniae. The procedure was successfully used for other Mollicutes. It detected ureaplasmas in urogenital swabs and corn stunt spiroplasmas in infected corn plants and leafhoppers. A modification of the technique has been developed that identifies mycoplasma colonies on agar. It has also been used to assay for antimycoplasma antibodies in serum.
A dense reference network for mass-market centimeter-accurate positioning (2016)

The quality of atmospheric corrections provided by a dense reference network for centimeter-accurate carrier-phase differential GNSS (CDGNSS) positioning is investigated. A dense reference network (less than 20 km inter-station distance) offers significant benefits for mass-market users, enabling low-cost (including single-frequency) CDGNSS positioning with rapid integer ambiguity resolution. Precise positioning on a mass-market platform would significantly influence the world economy, ushering in a host of consumer-focused applications such as globally-registered augmented and virtual reality and improved all-weather safety and efficiency for intelligent transportation systems, applications which have so far been hampered by the several-meter-level errors in standard GNSS positioning. This contribution examines CDGNSS integer ambiguity resolution performance in terms of network correction uncertainty, and network correction uncertainty, in turn, in terms of network density. It considers the total error in network corrections: a sum of ionospheric, tropospheric, and reference station multipath components. The paper's primary goal is to identify the network density beyond which mass-market users would see no further significant improvement in ambiguity resolution performance. It finishes by describing development and deployment of a low-cost dense reference network in Austin, Texas.
Experimental Demonstration of Incoherent Optical Multilevel Staggered-APSK (Amplitude- and Phase-Shift Keying) Signaling (2008)

Generation and incoherent detection of a 30-Gbit/s 8-level staggered APSK signal using two-state MLSE detection is successfully demonstrated with a 140-km fiber transmission. Its better constellation design results in 1.5-dB sensitivity improvement from 8-DPSK signaling.
Performance evaluation for AF relay TFI-OFDM systems (2015)

Amplify-and-forward (AF) relay transmissions can achieve a low power long distance communication. The problem of the AF method is that the channel state information (CSI) between source-relay (SR) and relay-destination (RD) should be obtained simultaneously in the destination node. The pilot signal is inserted to obtain the CSI, and the time frequency interferometry (TFI) method can reduce the number of pilot signals and the channel estimation (CE) power. This paper proposes the low power CE for AF relay transmissions in an orthogonal frequency division multiplexing based on the TFI method.
Facile Approach to Recycling Highly Cross-Linked Thermoset Silicone Resins under Ambient Conditions (2019)

Silicone resins are traditional thermoset polymers with an inorganic backbone, affording chemical inertness and high thermal stability, which also makes them inherently difficult to recycle by traditional methods. Here, we demonstrate that catalytic amounts of fluoride ion at room temperature solubilize highly cross-linked silicone resins initially cured up to 250 °C. After solubilization equilibria are achieved, solvent is removed to reform the polymer network. Coatings on aluminum substrates and monoliths of virgin and recycled silicone resins were evaluated for hydrophobicity, wear resistance, substrate adhesion, and thermal stability. Silicones recycled under optimized conditions retained nearly 100% wear resistance, thermal stability, and adhesion properties. In some instances, the recycled coatings offer properties superior to the initial materials.
Abstract 3245: The Golgi protein GLG1 participates in tumor progression (2012)

Abstract Increasing evidence suggests that endocytosis and membrane trafficking are deregulated in cancer cells. Because of their dependence on selected signaling pathways, tumor cells may need to rely on accelerated receptor recycling and increased secretion of a variety of molecules such as matrix components, adhesion molecules and growth factors. Mass spectrometry analysis of proteins associated with separase, recently shown to be an important regulator of membrane trafficking, identified the Golgi apparatus protein 1 (GLG1). GLG1 is primarily known as an E-selectin ligand that mediates the initial step of tethering and rolling of leukocytes on vascular endothelium. We therefore addressed the possibility that GLG1 could play a similar role in circulating tumor cells, facilitating arrest and extravasation into adjacent tissues. Consistent with this possibility, tail vein injection of stably GLG1-depleted tumor cells into NOD/SCID mice resulted in reduced numbers of metastatic nodules. Moreover, metastatic tumor growth was almost exclusively intravascular, indicating impaired extravasation of tumor cells. Further investigation, however, showed that, in tumor cells, GLG1 is almost exclusively localized to the Golgi apparatus, challenging the notion that it plays a direct role in mediating tumor cell adhesion to endothelium as in leukocytes. To elucidate the molecular mechanisms by which GLG1 could affect tumor cell migration through interactions at the Golgi level, we conducted experiments using GLG1-depleted human tumor cell lines. Transient silencing of GLG1 by siRNA was observed to modify cell shape (elongated morphology), to markedly alter Golgi architecture, to inhibit migration of a range of tumor cell lines, and to decrease β1 integrin protein level and impair its internalization/recycling. In addition, subsequent experiments led to the identification of BIG1, an Arf-GEF required to initiate membrane vesicle formation by promoting guanine-nucleotide exchange on Arf1 and Arf3, as a new interactor of GLG1. Taken together, our observations provide insight into a novel and specific role of GLG1 in tumor progression by affecting, thanks to its privileged position in the secretory pathway, trafficking of key molecules implicated in cell migration. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 103rd Annual Meeting of the American Association for Cancer Research; 2012 Mar 31-Apr 4; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2012;72(8 Suppl):Abstract nr 3245. doi:1538-7445.AM2012-3245
Renal repair and recovery (2008)

Experimental animal models of AKI demonstrate that renal recovery and repair involves proliferation of tubular epithelial cells and stem cell populations and the coordinated contribution of multiple growth factors. Future efforts to improve recovery from AKI and improve patient outcomes may include novel therapies based on manipulation of populations of stem cells and augmenting repopulation of renal tubules.
MicroBubble activated acoustic cell sorting (2017)

Acoustophoresis, the ability to acoustically manipulate particles and cells inside a microfluidic channel, is a critical enabling technology for cell-sorting applications. However, one of the major impediments for routine use of acoustophoresis at clinical laboratory has been the reliance on the inherent physical properties of cells for separation. Here, we present a microfluidic-based microBubble-Activated Acoustic Cell Sorting (BAACS) method that rely on the specific binding of target cells to microbubbles conjugated with specific antibodies on their surface for continuous cell separation using ultrasonic standing wave. In acoustophoresis, cells being positive acoustic contrast particles migrate to pressure nodes. On the contrary, air-filled polymer-shelled microbubbles being strong negative acoustic contrast particles migrate to pressure antinodes and can be used to selectively migrate target cells. As a proof of principle, we demonstrate the separation of cancer cell line in a suspension with better than 75% efficiency. Moreover, 100% of the microbubble-cell conjugates migrated to the anti-node. Hence a better upstream affinity-capture has the potential to provide higher sorting efficiency. The BAACS technique expands the acoustic cell manipulation possibilities and offers cell-sorting solutions suited for applications at point of care.
Properties of a Conidial-bound Cellulase Enzyme System from Trichoderma reesei (1988)

Conidia of Trichoderma reesei QM 9414 are able to degrade crystalline cellulose to glucose in the absence of protein synthesis, indicating the presence of a cellulase enzyme system. Measurement of enzyme activities revealed the presence of several glycanases and glycosidases. The cellulase enzyme system appeared irrespective of the conditions applied to induce conidiation. Removal of the endo-1,4-β-glucanase from the cellulase system could be achieved by treatment of conidia with β-octylglucoside or Triton X-100. Conidia treated in this way grew poorly on cellulose but well on glycerol. The endo-1,4-β-glucanase released from conidia by β-octylglucoside appeared as a single enzyme upon SDS-PAGE/immunoblotting with an apparent molecular mass of 68 kDa, an isoelectric point of 4·8–5·3, and a pH optimum between pH 4–6. These properties were similar to endo-1,4-β-glucanase I purified from culture filtrates of cellulose-grown T. reesei. Thermostability of the released enzyme was, however, lower than that of endo-1,4-β-glucanase I. Germination of T. reesei conidia in a medium containing glycerol as a carbon source led to a loss of endo-1,4-β-glucanase activity which paralleled the decrease in the number of ungerminated conidia.
Direct visualization of photonic band structure for three-dimensional photonic crystals (2000)

We propose a method to experimentally determine the full photonic band structure of photonic crystals by monitoring the beam propagation, and we demonstrate the experimental results of the band-structure measurement in the near-infrared regime for ${\mathrm{S}\mathrm{i}/\mathrm{S}\mathrm{i}\mathrm{O}}_{2}$ three-dimensional hexagonal photonic crystals fabricated by autocloning bias-sputtering process.
Some Aspects of Current Interruption Physics in High Voltage Circuit Breakers (2014)

Abstract Recent results of experimental and theoretical investigations on current interruption processes are presented with a focus on SF 6 high voltage circuit breakers. Various aspects of thermal interruption at the zero crossing of the current are shown, including the scatter and the distribution of arc voltage shortly before CZ and the role of turbulence. The thermal interruption capability of air and CO 2 are compared to that of SF 6 . Investigations on the dielectric recovery are shown for SF 6 and CO 2 . The breakdown voltage during the dielectric recovery can be described by simple streamer and leader inception models. (© 2014 WILEY‐VCH Verlag GmbH &amp; Co. KGaA, Weinheim)