gebhart/patrepeval huggingface dataset:
The Tau Gene Locus and Frontotemporal Dementia (2004)

Frontotemporal lobar degeneration (FTLD) has become an increasingly recognised form of dementia. It has been demonstrated that a proportion of cases of FTLD result from mutations in the tau gene on chromosome 17. A pathological hallmark in the brains from patients with tau mutations is an accumulation of insoluble tau within neurons and glia that is considered neurotoxic. However, there are reports of families with FTLD linked to the tau locus on chromosome 17 in which no mutations have been found, and these families lack any accumulation of insoluble tau. Recently, two new tau mutations have been described that also appear to cause disease in the absence of any tau accumulation. The role of the tau locus and tau accumulation in contributing to the neurodegenerative process in chromosome-17-linked families without mutations and in families with tau mutations without insoluble tau is discussed.
3D Printing of Multilayered and Multimaterial Electronics: A Review (2021)

Abstract 3D printing, also known as additive manufacturing, is a manufacturing process in which the materials are deposited layer by layer in an additive manner. With the advancement in materials and manufacturing technology, 3D printing has found its applications in the field of electronics manufacturing. Initially, 3D printing is used for the fabrication of electronic components with single material designs such as resistors, inductors, circuits, antennas, strain gauges, etc. Recently, there are many works involving the use of 3D printing fabrication techniques for advanced electronic components and devices such as parallel plate capacitors, inductors, organic light‐emitting diodes, photovoltaics, transistors, displays, etc. which involve multilayer multimaterial printing. Despite these many works, there has been no review on the design and fabrication consideration for the 3D printing of multilayered and multimaterial (MLMM) electronics. As such, this review aims to summarize the current landscape of 3D printing of MLMM electronics and provide some insights on the design consideration, fabrication strategies, and challenges of 3D printing of MLMM electronics. In particular, the focus will be placed on discussing the interface conditions between different materials such as surface wettability, surface roughness, material compatibility, and the considerations for postprocessing treatments.
A PSEUDO-BINARY IN THE U-Cb-C SYSTEM (1958)

BS>During the course of investigations on U--Nb alloys an impurity was observed in several different alloys of various compositions. The impurity was metallographically identified as a carbide by its shape, quantity, and reaction with HNO/sub 3/ etchant. The metallographic results strongly support the x-ray- diffraction evidence that the unknown face-centered-cubic phase is a monocarbide of U and Nb. (W.L.H.)
Human papillomavirus type 16 (HPV16) E6/E7-specific cytotoxic T lymphocytes (CTL) for immunotherapy of HPV-associated cancer (Ca). (2012)

2558 Background: Vaccines prevent HPV-associated Ca, but their benefits in established Ca are disappointing: although these tumors express viral E6 and E7 antigens (Ags) immune responses are limited even after vaccination, likely due to negative environmental cues that block tumor recognition and T cell (TC) activation in vivo. We postulated that ex vivo stimulation of TCs in an immunologically favorable milieu would allow us to reactivate tumor-directed CTLs from Ca patients and benefit the recipients on reinfusion. Methods: We studied 68 patients with HPV+ Ca. To detect HPV16 E6/E7-specific TCs (HPV-TCs) in blood, we measured the IFNγ ELISpot responses of TCs stimulated by monocyte-derived dendritic cells (DCs) loaded with pepmixes (peptide libraries of 15-mers overlapping by 11 aa) spanning E6/E7. Because HPV-TCs from these patients may be anergized by their tumors, potent Ag presenting strategies might be required for reactivation, and thus we stimulated these cells in the presence of IL-6, -7, -12 and -15, as we have shown that these can induce responses to poorly immunogenic Ags. Results: We successfully reactivated HPV-TCs from 8/16 cervical and 33/52 oropharyngeal Ca patients. We could expand these HPV-TCs to clinically useful numbers by using patient B-cell blasts (BBs) as APCs. Stimulation of DC-stimulated HPV-TCs by E6/E7 pepmix-loaded BBs further expanded (3.8 ± 1.5×/round) HPV-TC lines, which phenotypically are almost exclusively composed of TCs (98 ± 3% CD3+), with a variable proportion of mostly effector memory (CD45RA–, CD45RO+, CD62L– and CCR7–) CD4+ and CD8+ cells (37 ± 28% and 49 ± 27%, respectively). The viral/tumor associated epitopes recognized mapped to E6 aa 49-71, 77-91 and 125-143, and E7 aa 1-19 and 73-87. The expanded cells from patients killed E6/E7+ targets (specific lysis up to 45-61% vs. 0-8% in controls, 40:1 E:T ratio). Conclusions: We have developed a system that allows the robust generation of HPV-directed CTLs from patients with HPV16+ Ca, which recognize specific epitopes in tumor-associated Ags. Our lines have the potential to be used for adoptive cellular immunotherapy of HPV+ Ca.
Daily Movements of the Treefrog, Hyla andersoni (1986)

, AND R. A. BALLINGER. 1979. Food resource utilization during periods of low and high food availability in Sceloporus jarrovi (Sauria: Iguanidae). Southwest. Nat. 24:347-363. HEATWOLE, H. 1977. Habitat selection in reptiles. In C. Gans and D. W. Tinkle (eds.), Biology of the Reptilia. Vol. 7. Pp. 137-155. Academic Press, New York. MOERMOND, T. C. 1979a. The influence of habitat structure on Anolis foraging behavior. Behaviour 70:147-167. 1979b. Habitat constraints on the behav-
All-optical wavelength conversion in silicon wire waveguides (2005)

We describe the use of two-photon absorption process in submicron silicon wire waveguides for all-optical wavelength conversion by cross-absorption modulation scheme. Optical pulses of 1.6 ps at 1 GHz repetition rate have been successfully converted from 1550 nm to 1544 nm. (2 pages)
Automatic image style transfer using emotion-palette (2018)

Palette-based color editing can form an intuitive interface through which novices can perform interesting color modifications. However, because such modifications involve pixel-level operations, considerable labor is needed to accomplish an image’s emotion transformation. In this paper, we propose a novel color-transferring framework for image based on palettes to evoke different emotions. The purpose is to use the emotion-related color combinations to change the picture's original color palette to obtain stylized images. For an input image, the optimized k-medoids algorithm is used to create a set of the most representative color palettes. The system search for the best color combinations from a predefined database according to the color palette characteristics of the input image. Finally, using the selected emotion-palette we conduct a color transfer. The novel method can transfer a wide range of image into a new color style depicting the required emotional impact.
Lightweight electromagnetic shields using optimized polyaniline composites in the microwave band (2007)

Abstract A genetic algorithm (GA) was used to optimize a multilayer electromagnetic shield of polyaniline (PANI)–polyurethane (PU) conducting composites in the microwave band. First, the electronic properties of freestanding films with different mass fractions of polyaniline were studied. A very low percolation threshold (0.2%) was found, with a maximum of conductivity of 10 4 S/m. Second, the electromagnetic shielding effectiveness of the films were investigated in the X and Ku bands (8.2–18 GHz), showing an attenuation increase of 1–40 dB with the mass fraction of polyaniline in the blends. Then, the electromagnetic shielding properties of multi‐layered PAni–PU composites were investigated in order to obtain an attenuation superior to 40 or 80 dB, depending on the application. To improve the performances of the electromagnetic shields, three‐layered PAni–PU composites were made, using an optimization method. The intrinsic physical parameters of the composites were used as a database for the optimization calculation. The optimization results showed that materials with a thickness of &lt;500 µm could answer many industrial or military shielding applications. As the electronic properties can be tuned easily with the mass fraction of polyaniline in the blends, conducting multi‐layered composite materials can be made following the results of the optimization. Their electromagnetic shielding effectiveness was measured, showing good agreement between the measurements and modeling. These results demonstrated that the genetic algorithm allows us to conceive lightweight and high performance electromagnetic shields using intrinsically conducting polymers. The mass per unit of surface of the shield was &lt;200 g/m 2 , giving potential applications in the aeronautics domain. Copyright © 2007 John Wiley &amp; Sons, Ltd.
Reconstruction of curved-surface bodies from a set of imperfect projections (1977)

A procedure is described for obtaining the description of solid bodies from a set of pictures taken from different vantage points. The bodies are assumed to be bounded by faces which are planar or quadric, and to have vertices formed by exactly three faces. The line and junction information provided to the program by the preprocessor is assumed to contain defects such as missing lines or wrongly classified junction types. The procedure is able to build a description of the bodies in spite of a moderate number of such imperfections. Use is made of a set of new grammar rules for line-drawing projections of curved and planar bodies. (Author)
Improved genome-wide localization by ChIP-chip using double-round T7 RNA polymerase-based amplification (2008)

Chromatin immunoprecipitation combined with DNA microarrays (ChIP-chip) is a powerful technique to detect in vivo protein-DNA interactions. Due to low yields, ChIP assays of transcription factors generally require amplification of immunoprecipitated genomic DNA. Here, we present an adapted linear amplification method that involves two rounds of T7 RNA polymerase amplification (double-T7). Using this we could successfully amplify as little as 0.4 ng of ChIP DNA to sufficient amounts for microarray analysis. In addition, we compared the double-T7 method to the ligation-mediated polymerase chain reaction (LM-PCR) method in a ChIP-chip of the yeast transcription factor Gsm1p. The double-T7 protocol showed lower noise levels and stronger binding signals compared to LM-PCR. Both LM-PCR and double-T7 identified strongly bound genomic regions, but the double-T7 method increased sensitivity and specificity to allow detection of weaker binding sites.
Microwave Electrodynamics of low TC and high TC Systems with Coexisting Superconductivity and Magnetism (2000)

We investigate the microwave electrodynamics of both artificial low T C superconducting/magnetic (S/M) layered structures and high T C cuprates. In particular we focus on Nb/CuMn (superconducting/spin-glass) bilayers, and on GbBa 2 Cu 3 O 7-δ (GBCO) thin films, which show coexistence of superconductivity and long range ordered antiferromagnetism below T N = 2.2 K . In both cases we are interested in the influence of magnetism on superconducivity. Moreover, in the GBCO case, we want to shed light on the problem of the determination of the pairing symmetry in the cuprates. First we show surface impedance data at 10 GHz on Nb/CuMn bilayers. We extract information about the induced order parameter in the magnetic layer and we compare it with the exotic behavior predicted for S/M proximity systems. Then we present microwave surface impedance data at three different frequencies on GBCO c-axis oriented epitaxial thin films. Both the resistance and the reactance data on GBCO show an unusual low temperature behavior, mainly due to change in magnetic permeability. This result indicates that the paramagnetism of the rare-earth ions has to be taken into account when extracting the superconducting penetration depth as a function of temperature, and thus determining the pairing state symmetry of the cuprates.
Active Estimation of F-Measures (2010)

We address the problem of estimating the Fα-measure of a given model as accurately as possible on a fixed labeling budget. This problem occurs whenever an estimate cannot be obtained from held-out training data; for instance, when data that have been used to train the model are held back for reasons of privacy or do not reflect the test distribution. In this case, new test instances have to be drawn and labeled at a cost. An active estimation procedure selects instances according to an instrumental sampling distribution. An analysis of the sources of estimation error leads to an optimal sampling distribution that minimizes estimator variance. We explore conditions under which active estimates of Fα-measures are more accurate than estimates based on instances sampled from the test distribution. 1
Masturbation, Madness, and the Modern Concepts of Childhood and Adolescence (1975)

Masturbation, Madness, and the Modern Concepts of Childhood and Adolescence R. P. Neuman R. P. Neuman State University College, Fredonia, New York Search for other works by this author on: Oxford Academic Google Scholar Journal of Social History, Volume 8, Issue 3, Spring 1975, Pages 1–27, https://doi.org/10.1353/jsh/8.3.1 Published: 01 March 1975
Outcomes Following Major Oncologic Operations for Non‐AIDS‐Defining Cancers in the HIV Population: A Matched Comparison to the General Population (2019)

Our findings are hypothesis generating and highlight the potential safety of major cancer surgery in the HIV population. However, care providers need be cognizant of the potential increased risk of post-operative complications following pulmonary lobectomy and the potential for increased length of stay. These findings are an initial insight into quality of care and outcomes metrics on HIV patients undergoing major cancer operations.
Employee Work Experiences, Feelings, and Morality (2023)

Since the late 1990s, organizational psychology has gone through an “affective revolution,” producing a large body of work demonstrating how emotions and feelings are part and parcel of organizational life that have far-reaching effects on employees’ attitudes, cognitions, and behaviors. This stream of research has been particularly important in providing new insights into the origins of (im)moral behavior in the workplace—while (im)moral behavior was traditionally thought to be a result of <italic>personality</italic>, i.e., individuals with certain traits would be predisposed to engage in deviant behaviors, organizational psychologists now know that employees’ daily emotions too may facilitate (or inhibit) moral behavior. It is therefore important to have a comprehensive understanding of not only how and why emotions may influence moral behavior, but also the antecedents and predictors of these affective states, such as employees’ experiences of workplace events. Further, emotions may be studied not only as broad, diffuse states of positive and negative affect but also as discrete emotions (e.g., anger, happiness, anxiety, and guilt). Particularly relevant to the discussion of moral behaviors are the moral emotions of empathy and compassion, guilt, shame, and gratitude. Examining these discrete emotions (as opposed to broad positive and negative affective states) would allow for a more nuanced and comprehensive understanding of how the individual discrete emotions may influence (or be influenced by) employees’ moral cognitions—moral disengagement and moral licensing, and subsequently their moral behaviors (counterproductive work behaviors and organizational citizenship behaviors). For instance, while gratitude is often thought of as a self-transcendent, moral emotion that encourages prosocial and ethical behaviors, it is possible that under specific situations, feelings of gratitude may instead facilitate moral disengagement or moral licensing strategies, and free employees to perform unethical behaviors instead. Similarly, guilt, shame, and compassion too may have complex relationships with the moral cognitions and behaviors. Finally, while much of emotions research involves within-individual, fluctuating emotional and psychological states, it would be remiss to neglect these relationships within the context of individual differences (e.g., propensity to feel guilt and shame, empathy).
E-Books in der Schule: Eine Evaluierung von E-Book-Formaten und E-Book-Readern hinsichtlich ihrer Eignung für Schulbücher (2012)

Das Schulbuch ist als Lehrmittel unserer Zeit kaum mehr wegzudenken, obwohl es noch gar nicht so lange her war, dass man auch ohne auskam. Seit der Jahrtausendwende halten die digitalen Technologien im Sog des World Wide Web immer mehr Einzug im Klassenzimmer und spätestens seit der Einführung des iPads der Firma Apple bzw. des Kindle von Amazon.com nimmt die Diskussion rund um E-Books immer mehr zu. In diesem Beitrag soll versucht werden die derzeitigen Möglichkeiten zu beleuchten und der Frage nach zu gehen, ob aus technischer Sicht Schulbücher als E-Book denkbar sind. Neben der Frage „Was denn ein gutes Schulbuch ist“, werden E-Book-Formate und E-Book-Endgeräte dargestellt und anhand von praktischen Tests gezeigt, wo die Grenzen der Technik sind. Es kann zusammengefasst werden, dass es aus Sicht der Autoren völlig klar ist, dass die Digitalisierung von Büchern weiter voranschreitet, aber dass es bis zum Einsatz in der Praxis noch ein großer Schritt ist.
Synthesis of Silica-Gel-Supported Sulfur-Capped PAMAM Dendrimers for Efficient Hg(II) Adsorption: Experimental and DFT Study (2016)

A series of silica-gel-supported sulfur-capped PAMAM dendrimers (SiO2-G0-MITC–SiO2-G2.0-MITC) were synthesized and used for the adsorption of Hg(II) from aqueous solution. The optimum adsorption pH was found to be 6. Adsorption kinetics indicated that equilibrium can be approached in about 220 min and that the adsorption capacity increased with increasing generation of sulfur-capped PAMAM dendrimers. The kinetics of the adsorption process was found to be controlled by film diffusion and to follow a pseudo-second-order model. The adsorption isotherms were fitted well by the Langmuir isotherm model, and adsorption was found to take place by a chemical mechanism. Thermodynamic analysis demonstrated that the adsorption was a spontaneous, endothermic, and randomness-increasing process. Adsorption selectivity experiments showed that SiO2-G0-MITC–SiO2-G2.0-MITC can selectively adsorb Hg(II) from binary systems containing Hg(II) with Ni(II), Cd(II), Fe(III), and Zn(II). DFT calculations revealed that G0-MITC interacts with Hg(II) through the S atom in a monocoordinated manner, whereas G1.0-MITC behaves as a pentadentate ligand to coordinate with Hg(II) through the N atom of the tertiary amine group, the O atoms of the amide groups, and the S atoms. Charge transfer from G0-MITC and G1.0-MITC to Hg(II) was found to occur during the adsorption process.
High Bulk Electron Mobility Diketopyrrolopyrrole Copolymers with Perfluorothiophene (2015)

Adv. Funct. Mater, 2015, 18, 2725 Table 2 of the article was erroneously published with an extra column. The correct table can be found below. The editors apologize for any confusion.
A Personal Approach to Instructional Development (1980)

size of American colleges and universities, the seven ties saw an increased concern about the quality of educa tion available at these institutions. The problem of provid ing a high-caliber experience for students has captured the attention of many faculty members and the scrutiny of institutional officers. They have created any number of programs and agencies to develop effective measures for enhancing the quality of education.
Insights on the Interfacial Processes Involved in the Mechanical and Redox Stability of the BaCe0.65Zr0.20Y0.15O3−δ–Ce0.85Gd0.15O2−δ Composite (2020)

Ceramic fuel cells and H2 permeation membranes are key technologies to accelerate the transition from a carbon economy based on fossil fuels to a H2 economy based on the use of renewable resources. The competitiveness of these technologies in the market depends on the identification and optimization of stable and effective low-cost materials. Perovskite-fluorite ceria-based composites show suitable properties, and studies on the mechanism that rules their mechanical, thermal, and redox stability are crucial for further technological advances. This study focuses on the redox behavior of BaCe0.65Zr0.20Y0.15O3-?-Ce0.85Gd0.15O2-? (BCZY-GDC) dual-phase ceramic. Temperature-programmed reduction, thermogravimetry, temperature-dependent X-ray diffraction, and Raman analyses are used to understand the dynamics of the interaction between the ceramic oxide components. It is shown how the simultaneous occurrence of structural changes in BCZY and GDC reduction helps in decreasing the mechanical stresses induced by temperature and by the reducing atmosphere. The interfacial processes between the single GDC and BCZY oxides contribute to limit reduction of GDC in the composite, which allows complete reversibility of the redox process investigated in this study. Thus, it is suggested that the redox behavior of this class of materials may be a descriptor of their mechanical and thermal stability.
Synergistic Effect between TiO2, Zirconium and Carbon in the Photodegradation of Methyl Orange and Methylene Blue (2013)

The photocatalytic behaviour of TiO 2 prepared from titanium (IV) ethoxide was determined with regard to the decomposition of methyl orange (MO) and methylene blue (MB) dyes, respectively. In addition, we compared the behaviour of TiO 2 photocatalysts prepared in a similar fashion but which were (1) doped with different amounts of zirconium, (2) mixed with active carbon and (3) doped with different amounts of zirconium and mixed with active carbon. All of the TiO 2 samples were found to be mesoporous with some microporosity having an average particle size between 200 and 500 nm and with anatase crystallographic modification. The kinetics of the MO and MB dyes' photocatalytic degradation fitted well with the Langmuir–Hinshelwood model and were found to follow pseudo-first-order kinetics. The rates were highest for the TiO 2 samples doped with both Zr and mixed with the activated carbon. Characterization of these TiO 2 photocatalysts was carried out by X-ray diffraction, scanning electron microscopy and adsorption studies.
ChemInform Abstract: Ethynologues of Triphenylmethane Dyes. Part 9. 3,6‐Bis(dimethylamino)fluorenylium Dye Ethynologues: New Highly Coloured π‐Electron Systems. (1990)

Abstract 3,6‐Bis(dimethylamino)fluorenone (I) is coupled with the potassium arylacetylides (II) to produce the arylalkynylfluorenols (III) which are converted into the fluorenylium salts (V) by treatment with perchloric or tetrafluoroboric acid (IV).
Flexible Cu(In,Ga)Se2 solar cells fabricated using alkali-silicate glass thin layers as an alkali source material (2008)

Flexible Cu(In,Ga)Se2 (CIGS) solar cells were fabricated using alkali-silicate glass thin layers (ASTL) as an alkali source material deposited on various flexible substrates prior to the Mo backcontact layer deposition. Control of univalent alkali metal incorporation into the CIGS layer with the use of ASTL was demonstrated regardless of the presence of other multivalent metal impurities in ASTL. Dramatic enhancement in cell efficiencies using ASTL was observed though the use of excessively thick ASTL led to a degradation in cell performance. The quantum efficiency curves of CIGS solar cells fabricated using ASTL showed enhanced absorption in the long wavelength region. The photovoltaic performance dependence on a variety of substrate materials is also discussed.