gebhart/patrepeval huggingface dataset:
Stroke patients from rural areas have lower chances for long-term good clinical outcome after mechanical thrombectomy (2021)

Stroke patients from RA undergoing thrombectomy had worse functional outcome compared to UA patients. Since the benefit of MT is time dependent, urban-rural differences in stroke outcome probably result from the longer time from stroke onset to reperfusion treatment in RA patients.
The Growth Morphology and Nucleation Mechanism of Primary Ll<sub>2</sub> Al<sub>3</sub>Sc Particles in Al-Sc Alloys (2000)

The role of the nucleation mechanism and growth morphology of primary Ll 2 , Al 3 Sc, particles in the grain refinement of Al castings has been investigated using a simple hypereutectic, binary Al-Sc alloy. New evidence suggests a two-stage grain refining mechanism: the primary Al3Sc particles first nucleate on impurities in the melt (possibly Sc 2 O 3 ) before nucleating the α-Al grains. The primary particles grow as faceted dendrites that maintain an overall cubic morphology. High resolution EBSD analysis has shown that α-Al nucleates from Al 3 Sc particles with either an epitaxial, or a twin relationship below the eutectic temperature. α-Al then grows outwards as a single phase, pushing particles that did not act as nucleation centres to the grain boundaries. Some α-Al + Al 3 Sc eutectic is formed at the grain boundaries during the last stages of freezing.
Calmodulin inhibitors from the bitter mushroom Naematoloma fasciculare (Fr.) KARST. (Strophariaceae) and absolute configuration of fasciculols. (1985)

Calmodulin inhibitors were found in the bitter poisonous mushroom Naematoloma fasciculare (Fr.) KARST. (Strophariaceae). The active compounds, fasciculols B, C, and F, were isolated by droplet counter-current chromatography and identified on the basis of various physical and spectral data. Application of the dibenzoate chirality method to a p-bromobenzoate derivative of fasciculol C allowed the absolute configurations at the C-2 and C-3 positions to be determined as (R) and (S), respectively.
Synthesis of Chain Type and Fused ^|^pi;-Conjugated Phosphole Derivatives (2012)

Phosphole has a low aromaticity and exhibits characteristic optical and electrochemical properties derived from the phosphorus-bridged 1,3-diene π system. In addition, phosphole has an active lone pair at phosphorus. The most remarkable feature of the phosphole-based π-systems is that their fundamental properties are tunable by chemical functionalizations at the phosphorus center. In this regard, phosphole-based π-systems are now regarded as one of the future materials for use in optoelectronics. In this article, we would like to briefly summarize our recent results on the synthesis of novel π-conjugated phosphole derivatives with representative examples, which contain phosphole-vinylene, phosphole-acetylene, phosphole-heterole, phosphole-benzene, phosphole-phosphole, benzo[c]phosphole, acenaphtho[c]phoshole, and diacenaphtho[b,d]phosphole skeletons. The target compounds were successfully prepared by two main approaches, titanacycle method and Stille coupling. Selected structural, optical, and electrochemical data for a few derivatives are also presented. The results described herein would give valuable information and guidelines for designing phosphole-based opto-electrochemical materials.
New Proteinaceous ±-Amylase Inhibitor (Paim) fromStreptomyces corchorusii (1983)

Journal Article New Proteinaceous ±-Amylase Inhibitor (Paim) from Streptomyces corchorusii Get access Sawao Murao, Sawao Murao Department of Agricultural Chemistry, College of Agriculture, University of Osaka Prefecture, Japan Search for other works by this author on: Oxford Academic Google Scholar Naoki Oouchi, Naoki Oouchi Department of Agricultural Chemistry, College of Agriculture, University of Osaka Prefecture, Japan Search for other works by this author on: Oxford Academic Google Scholar Akira Goto, Akira Goto Department of Agricultural Chemistry, College of Agriculture, University of Osaka Prefecture, Japan Search for other works by this author on: Oxford Academic Google Scholar Motoo Arm Motoo Arm Department of Agricultural Chemistry, College of Agriculture, University of Osaka Prefecture, Japan Search for other works by this author on: Oxford Academic Google Scholar Agricultural and Biological Chemistry, Volume 47, Issue 2, 1 February 1983, Pages 453–454, https://doi.org/10.1080/00021369.1983.10865660 Published: 01 February 1983 Article history Received: 28 October 1982 Published: 01 February 1983
Phase 1/2 study of immunotherapy with dendritic cells pulsed with autologous tumor lysate in patients with refractory bone and soft tissue sarcoma (2017)

Although DC therapy appears safe and resulted in an immunological response in patients with refractory sarcoma, it resulted in an improvement of the clinical outcome in only a small number of patients. Cancer 2017;123:1576-1584. © 2017 American Cancer Society.
Cavity QED: applications to quantum computation (2004)

Possible schemes to implement the basic quantum gates for quantum computation have been presented based on cavity quantum electrodynamics (QED) systems. We then discuss schemes to implement several important quantum algorithms such as the discrete quantum fourier transform (QFT) algorithm and Grover's quantum search algorithm based on these quantum gates. Some other applications of cavity QED based systems including the implementations of a quantum disentanglement eraser and an entanglement amplifier are also discussed.
Assessing trophic interactions among three tuna species in the Solomon Islands based on stomach contents and stable isotopes (2022)

Trophic research is essential to the conservation and management of fishery resources. This study analyzed the feeding habits and nutritional interactions among three tuna species in the waters of the Solomon Islands (5°12′S–15°20′S, 157°31′E–172°19′E). A total of 103 bigeye tuna ( Thunnus obesus ), 296 yellowfin tuna ( Thunnus albacores ), and 264 albacore tuna ( Thunnus alalunga ) samples were collected from September to December 2019. Samples for stomach content and stable isotope analysis were randomly selected. The stomach content analysis results showed that the stomach contents of the three tuna species were rich in prey, and 48 prey species were identified, including fish, cephalopods, and crustaceans, with high between-phenotype component (BPC). Yellowfin tuna consumed the largest variety of food and bigeye tuna consumed the smallest. The feeding intensity of bigeye tuna were higher than that of yellowfin and albacore tuna. Yellowfin tuna had the highest empty stomach rate (35.69%) and lowest average stomach fullness index (0.064). The degree of stomach fullness in the three tuna species was mainly 1, and the difference in the stomach fullness index among them was significant ( P &amp;lt;0.001). Food overlap (0.3–0.6) and Levins index (&amp;lt;0.6) among the three species were low, indicating a specialized feeding tendency. Bigeye tuna mainly feed on Ommastrephes bartrami and Myctophidae, yellowfin tuna mainly feed on Hyperiidea and Aluterus monoceros , and albacore tuna mainly feed on Gempylus serpens and Loligo chinensis . The stable isotope results showed that the δ 13 C and δ 15 N values of the three tuna species were significant ( P &amp;lt;0.001). The standard ellipse area corrected for small sample sizes (SEAc) and total niche area (TA) of bigeye tuna, range of δ 15 N (NR) of yellowfin tuna, and range of δ 13 C (CR) of albacore tuna were the highest. The results of this study will help improve our understanding of the feeding ecology of these three tuna species and their important roles in the ecosystem and food web structure.
Overview on Clinical Features of Opioid-Induced Hyperalgesia (2009)

Opioids produce analgesia through a primarily inhibitory effect on the noci-ceptive system. To date, opioids remain the most powerful analgesics for clinicalmanagement of moderate to severe pain. Besides many known side effects ofopioids such as sedation and constipation, chronic opioid exposure is associatedwith the development of tolerance to opioid analgesics. This process is largelydue to an adaptive change of the opioid analgesic system that leads to thedesensitization of opioid receptors and associated intracellular cascades.
ChemInform Abstract: Some Applications of the Regioselective Lithiation of α‐Carbolines. (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
PIE: A Platform-wide TEE (2020)

While modern computing architectures rely on specialized hardware such as accelerators to provide performance and functionality, trusted execution environments (TEEs), one of the most promising recent developments in security, can only protect code confined in the CPU, limiting TEEs potential and applicability to a handful of applications. We observe that the TEEs' hardware trusted computing base (TCB) is fixed at design time, forcing users to rely on (mostly untrustworthy) software to allow peripherals into the TEE. Based on this observation, we propose PIE, a secure platform design with a configurable hardware and software TCB, which allows us to support specialized hardware while ensuring the least privilege principle. We introduce two new security properties relevant to such systems: platform-wide attestation and platform awareness. Platform-wide attestation allows to remotely verify the platform's current state, including the state of specialized hardware devices and how they are connected with each other, whereas platform awareness defines how the enclave reacts upon a change in connected devices. Together, these allow to attest to the hardware configuration of a system and check that only the trusted hardware with the right version of its firmware is part of the TCB (platform-wide attestation) and will stay part of the TCB for the whole execution (platform awareness). Finally, we present a prototype of PIE based on RISC-V's Keystone to show that such systems are feasible with only around 600 lines added to the software TCB, without compromising performance.
Cell Mediated Immune Response in Obese and Non-obese Women (2008)

Obesity has been associated with a number of adverse health outcomes in particular chronic inflammation and cardiovascular disease. The following immune function markers were analyzed: Immuknow™ Cell Mediated Immune Assay (CMI), Interleukin 6 (IL-6), White Blood Cell Count (WBC), and CD4 percent. PURPOSE: The purpose of this investigation is to determine if a larger Body Mass Index (BMI) has an effect on the CMI response. METHODS: Each participant was screened for items that could potentially alter immune function. The participants were divided into two groups based on BMI: nonobese (<25 kg/m2) and obese (>30 Eight apparently healthy (non-obese) women (28.3 ± 6.8) years of age, BMI (kg/m2) = (23 ± 2), waist circumference (in.) = (29.1 ± 2.8), % fat = (22.6 ± 4.5) and nine obese women (28.1± 4.7) years of age, BMI = (39 ± 5), waist circumference (in.) = (42.4± 4.3), % fat (38.3 ± 3.0). Fasting blood samples were collected and analyzed for CMI, IL-6, WBC, and CD4 Percent. Differences in groups were determined by an independent samples t test. (p < 0.05 for all). RESULTS: The immune marker results for obese group: CMI marker (215.3 ± 134.4 ng/mL), IL-6 (<1.56 pg/mL), WBC (7.4 ± 2.3 K/μL), and CD4 (48.7 ± 6.1 %). The immune marker results for non-obese group: CMI marker (282.0 ± 139.0 ng/mL), IL-6 (<1.56 pg/mL), WBC (6.4 ± 2.5 K/μL), and CD4 (39.7 ± 4.3 %). The CMI, IL-6, and WBC were not different between groups. However, the CD4 percent was significantly different in the obese group as compared to the non-obese group (p=0.003). CONCLUSION: These findings suggest that higher CD4 percent values are attributed to having a higher BMI in women, but the CMI marker, IL-6, and WBC were not. The results of this study will be beneficial for future investigations.
Slotted FAMA: a MAC protocol for underwater acoustic networks (2006)

Long propagation delays and low bit rates of underwater acoustic networks make these systems fundamentally different from the packet radio networks. As a consequence, many of the network protocols designed for radio channels are either not applicable, or have extremely low efficiency over underwater acoustic channels. These facts necessitate a dedicated design of protocols for an underwater acoustic network. A medium access control (MAC) protocol suitable for an underwater acoustic network is proposed and analyzed. The protocol is based on a channel access discipline called floor acquisition multiple access (FAMA) which combines both carrier sensing (CS) and a dialogue between the source and receiver prior to data transmission. During the initial dialogue, control packets are exchanged between the source node and the intended destination node to avoid multiple transmissions at the same time. Special attention is paid to the networks that are not fully connected, in which nodes can be hidden from each other. The new protocol uses time slotting and is thus called slotted FAMA. Time slotting eliminates the need for excessively long control packets, thus providing savings in energy. Protocol performance in throughput and delay is assessed through simulation of a mobile <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">ad</i> <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">hoc</i> underwater network, showing the existence of optimal power level to be used for a given user density.
Modulation of keratin 1, 10 and involucrin expression as part of the complex response of the human keratinocyte cell line HaCaT to ultraviolet radiation (2013)

Skin exposure to ultraviolet (UV) light evokes a complex stress response in keratinocytes. Keratin filament organization provides structural stability and mechanical integrity of keratinocytes. Involucrin is a transglutaminase substrate protein contributing to the formation of insoluble cornified envelopes. However, a more complex role for keratins and involucrin has been proposed, including the regulation of cell stress response. The aim was to evaluate modulations of keratin 1, 10 and involucrin expression in HaCaT in the light of the complex response of these cells to UV-B radiation, including effects on c-Jun and matrix metalloproteinase 1 (MMP-1) gene expression and production of interleukin (IL) 6 and 8. A UV-B (300±5 nm) dose of 10 mJ/cm(2) was selected since this dose resulted in a partial decrease in cell viability in contrast to higher UV-B doses, which induced complete cell death 48 h after treatment. The UV-B radiation induced significant expression of keratin 1 and 10 and decreased expression of involucrin. This was accompanied by increased expression of c-Jun and MMP-1 and IL-6 and IL-8 production. The data suggest that the expression of keratin 1, 10 and involucrin is modulated in HaCaT keratinocytes as a part of the complex stress response to UV radiation.
Mechanical and Dielectric Spectroscopy of Aroclor, 1,2-Polybutadiene, and Their Mixtures (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMechanical and Dielectric Spectroscopy of Aroclor, 1,2-Polybutadiene, and Their MixturesC. M. RolandCite this: Macromolecules 1995, 28, 9, 3463–3467Publication Date (Print):April 1, 1995Publication History Published online1 May 2002Published inissue 1 April 1995https://pubs.acs.org/doi/10.1021/ma00113a053https://doi.org/10.1021/ma00113a053research-articleACS PublicationsRequest reuse permissionsArticle Views122Altmetric-Citations33LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Mind from Matter (1985)

. . . a man should simply and profoundly say that he cannot understand how consciousness comes into existence is perfectly natural. But that a man should glue his eye to a microscope and stare and stare and stare and still not be able to see how it happens is ridiculous, and it is particularly ridiculous when it is supposed to be serious. ... If the natural sciences had been developed in Socrates' day as they are now, all the sophists would have been scientists. One would have hung a microscope outside his shop in order to attract custom, and then would have had a sign painted saying: Learn and see through a giant microscope how a man thinks (and on reading the advertisement Socrates would have said: That is how men who do not think behave).
A Human-in-the-Loop Investigation of Multi-Sector Planning Operations for the NextGen Mid-Term (2010)

A human-in-the-loop simulation was conducted to evaluate a concept for introducing multi-sector trajectory planning operations into en route air traffic facilities in the NextGen Mid-Term timeframe. Multi-sector planning tools and procedures for local area traffic flow management were developed, and then tested using two different service provider team configurations. In one condition, local area flow planning was performed by the traffic management coordinator and area supervisor. A second condition added a new, dedicated multi-sector planner position to the planning team. A set of eight convective weather and traffic load scenarios was used to evaluate the operational feasibility, potential benefits, and tool performance requirements of each condition. Significant improvements in weather avoidance and controller workload were observed in the multi-sector planner condition but no significant improvement was observed in user efficiency. Results indicate that multisector planning operations are effective and feasible in either team configuration. I.
Near-End Listening Enhancement in the Presence of Bandpass Noises (2012)

When using a mobile phone in acoustical background noise, the near-end listener perceives not only the (clean) far-end speech but also the ambient noise and thus experiences an increased listening effort and a possibly reduced speech intelligibility. Near-end listening enhancement processes the received far-end speech signal depending on the near-end background noise to improve intelligibility. However, in mobile phones it is often not possible to increase the audio power. In a previous contribution, the authors developed a recursive closed-form solution, which maximizes the Speech Intelligibility Index (SII) under the constraint of an unchanged average power of the audio signal. This solution, however, shows in bandpass noise environments a disadvantageous narrow bandpass characteristic of the processed speech even though the SII is optimal. Therefore, in this contribution, we analyze this algorithm and propose a new spectral weighting rule which prevents the narrow bandpass effect with only a marginal reduction in SII.
Design and fabrication of gold nanostructures with dispersed nanospheres for localized surface plasmon resonance applications (2008)

The design and fabrication of gold nanostructures through nanosphere lithography utilizing dispersed nanospheres, on glass substrate for the applications of localized surface plasmon resonance, were investigated in detail. The fabrication of the nanostructures was realized through the gold film deposition onto nanospheres dispersed on a substrate and the subsequent directional gold etching. Depending on the deposition and etching conditions of the gold, a variety of gold nanostructures can be fabricated. So far through this method, only 2D nanocrescents had been reported. However, either 2D or 3D non-conformal nanostructures are formed in this way, and the profiles of the obtainable nanostructures were simulated under various conditions. For nanostructures fabricated on glass, the simulated profiles coincided well with the fabricated ones. These results prove that our profile simulation program can realize the design of 2D and 3D nanostructures obtainable by dispersed nanospheres, and reduce the effort and cost for achieving desired nanostructures by experiments in the trial-and-error stage.
Rising to the GINA Asthma Challenge: thinking beyond just asthma (2012)

We would like to thank Z. Pond and co-workers for their interest in our recent editorial with regard to the Global Initiative for Asthma (GINA) Asthma Challenge We are also delighted by their enthusiasm, in terms of embracing this concept, and framing the issue in the context of their local population. We recognise that the GINA recommendations provide a framework for the management of asthma in the general population of patients [2], but it is also recognised, within the body of the document, that management needs to be individualised. As Z. Pond and co-workers have outlined patient management must go beyond the appropriate prescription of medications, but also take account of the sociocultural factors We also feel that the assessment of the phenotype of asthma patients should take account of these factors as they are likely to contribute to an increased risk of hospitalisation. We strongly recommend that others embrace this approach of adapting locally our global challenge to reduce asthma hospitalisations. We suggest that by using the GINA asthma strategy as a framework for achieving asthma control that we can move closer to achieving our ultimate aim of reducing morbidity and mortality associated with this global public health challenge. It should be noted that our challenge of a 50% reduction in hospitalisations is targeted at a general population level and we appreciate that this may not be feasible in a more specialised setting, such as Z.
On the sound production of the timpani (2004)

Abstract:- The acoustic features of kettledrums through modal analysis and acoustic radiation measure were investigated. Modal analysis exciting the system by a hammer and a shaker on two different kettledrums was studied. Through this analysis 15 vibration modes were found. Their mappings resulted very clear and defined. Acoustic radiation using two different parameters was measured. The first parameter, vp / , has been already used to measure acoustic radiation of the soundboard of a piano (Giordano), and of a harpsichord (Tronchin et al). The second, vp ⋅ , is a new parameter called intensity of acoustic radiation. This parameter resulted more linked to the frequency response function than vp /.