gebhart/patrepeval huggingface dataset:
Model Predictive Control of a Parafoil and Payload System (2004)

A model predictive control strategy is developed for an autonomous parafoil and payload system. Since the technique requires a linear dynamic model of the system, a reduced state linear model based on a nonlinear 6 degree-of-freedom parafoil and payload model is established and validated. In order to use the reduced state linear model for model predictive control the desired trajectory in the x-y plane is mapped into a desired heading angle using Lagrange interpolating polynomials. Flight test results demonstrate that this model predictive control strategy is a natural and effective method of achieving trajectory tracking in a parafoil and payload system.
Conveying Feature Tags with the Session Initiation Protocol (SIP) REFER Method (2006)

The SIP "Caller Preferences" extension defined in RFC 3840 provides a mechanism that allows a SIP request to convey information relating to the originator's capabilities and preferences for handling of that request.The SIP REFER method defined in RFC 3515 provides a mechanism that allows one party to induce another to initiate a SIP request.This document extends the REFER method to use the mechanism of RFC 3840.By doing so, the originator of a REFER may inform the recipient as to the characteristics of the target that the induced request is expected to reach.
Forward dynamic object-oriented program slicing (2003)

Object-oriented programming has been considered a most promising method in program development and maintenance. An important feature of object-oriented programs (OOPs) is their reusability which can be achieved through the inheritance of classes or reusable components. We propose an algorithm to decompose OOPs with respect to some variables or objects of interest using the forward dynamic slicing technique. The algorithm recursively decomposes constructors and member functions with respect to the specified variables in a slicing criterion. It is an extension of the interprocedural program slicing algorithm by Song and Huynh (1998) which is based on the forward slicing technique by Korel and Yalamanchili (1994). The algorithm analyzes message passings and parameter passings and constructs dynamic object relationship diagrams (DORD). As results, the algorithm produces not only the statement level slice (called traditional slice), but also the DORD that shows the relationships among the objects with respect to the specified variables in a slicing criterion.
Effect of acetylation on emulsifying properties of glycinin (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEffect of acetylation on emulsifying properties of glycininKang S. Kim and Joon S. RheeCite this: J. Agric. Food Chem. 1990, 38, 3, 669–674Publication Date (Print):March 1, 1990Publication History Published online1 May 2002Published inissue 1 March 1990https://pubs.acs.org/doi/10.1021/jf00093a018https://doi.org/10.1021/jf00093a018research-articleACS PublicationsRequest reuse permissionsArticle Views101Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Evaluation of topical cysteamine therapy in the CTNS(-/-) knockout mouse using in vivo confocal microscopy. (2011)

Measurement of CVI shows that there is a progressive increase in cystine crystal volume up to 8 months of age and that cysteamine eyedrops significantly inhibits progression in the Ctns(-/-) mouse. These findings are similar to those seen clinically in patients with cystinosis, and suggest that measurement of CVI in the Ctns(-/-) mouse may be used as a model to develop novel therapeutic strategies for treating corneal cystinosis.
How should we diagnose and treat blastic plasmacytoid dendritic cell neoplasm patients? (2019)

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive leukemia for which we developed a nationwide network to collect data from new cases diagnosed in France. In a retrospective, observational study of 86 patients (2000-2013), we described clinical and biological data focusing on morphologies and immunophenotype. We found expression of markers associated with plasmacytoid dendritic cell origin (HLA-DRhigh, CD303+, CD304+, and cTCL1+) plus CD4 and CD56 and frequent expression of isolated markers from the myeloid, B-, and T-lymphoid lineages, whereas specific markers (myeloperoxidase, CD14, cCD3, CD19, and cCD22) were not expressed. Fifty-one percent of cytogenetic abnormalities impact chromosomes 13, 12, 9, and 15. Myelemia was associated with an adverse prognosis. We categorized chemotherapeutic regimens into 5 groups: acute myeloid leukemia (AML)-like, acute lymphoid leukemia (ALL)-like, lymphoma (cyclophosphamide, doxorubicin, vincristine, and prednisone [CHOP])-like, high-dose methotrexate with asparaginase (Aspa-MTX) chemotherapies, and not otherwise specified (NOS) treatments. Thirty patients received allogeneic hematopoietic cell transplantation (allo-HCT), and 4 patients received autologous hematopoietic cell transplantation. There was no difference in survival between patients receiving AML-like, ALL-like, or Aspa-MTX regimens; survival was longer in patients who received AML-like, ALL-like, or Aspa-MTX regimens than in those who received CHOP-like regimens or NOS. Eleven patients are in persistent complete remission after allo-HCT with a median survival of 49 months vs 8 for other patients. Our series confirms a high response rate with a lower toxicity profile with the Aspa-MTX regimen, offering the best chance of access to hematopoietic cell transplantation and a possible cure.
Strokelets: A Learned Multi-scale Representation for Scene Text Recognition (2014)

Driven by the wide range of applications, scene text detection and recognition have become active research topics in computer vision. Though extensively studied, localizing and reading text in uncontrolled environments remain extremely challenging, due to various interference factors. In this paper, we propose a novel multi-scale representation for scene text recognition. This representation consists of a set of detectable primitives, termed as strokelets, which capture the essential substructures of characters at different granularities. Strokelets possess four distinctive advantages: (1) Usability: automatically learned from bounding box labels, (2) Robustness: insensitive to interference factors, (3) Generality: applicable to variant languages, and (4) Expressivity: effective at describing characters. Extensive experiments on standard benchmarks verify the advantages of strokelets and demonstrate the effectiveness of the proposed algorithm for text recognition.
Chemical Structure of Retro-2, a Compound That Protects Cells against Ribosome-Inactivating Proteins (2012)

Shiga-like toxins and ricin are ribosome-inactivating proteins (RIPs) that are lethal to mammals and pose a global health threat. No clinical vaccines or therapeutics currently exist to protect against these RIPs. Two small molecules (Retro-1 and Retro-2) were discovered with high-throughput screening and reported for their protection of cells against RIPs. Of great significance, Retro-2, reported as (E)-2-(((5-methylthiophen-2-yl)methylene)amino)-N-phenylbenzamide, fully protected mice from lethal nasal challenge with ricin. Herein, we report studies showing that the chemical structure of Retro-2 is (±)-2-(5-methylthiophen-2-yl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one rather than (E)-2-(((5-methylthiophen-2-yl)methylene)amino)-N-phenylbenzamide. The latter is an achiral molecule that converts spontaneously to the former, which is a racemate and showed cell protection against RIPs. This calls for attention to (±)-2-(5-methylthiophen-2-yl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one as a promising RIP inhibitor and for chemical characterization of drug leads obtained from high-throughput screens.
Enrichment and fortification of dairy products and margarine (1968)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEnrichment and fortification of dairy products and margarineSamuel T. Coulter and Elmer Lawrence. ThomasCite this: J. Agric. Food Chem. 1968, 16, 2, 158–162Publication Date (Print):March 1, 1968Publication History Published online1 May 2002Published inissue 1 March 1968https://pubs.acs.org/doi/10.1021/jf60156a011https://doi.org/10.1021/jf60156a011research-articleACS PublicationsRequest reuse permissionsArticle Views260Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Processing Conditions, Thermal and Mechanical Responses of Stretchable Poly (Lactic Acid)/Poly (Butylene Succinate) Films (2017)

Poly (lactic acid) (PLA) and poly (butylene succinate) (PBS) based films containing two different plasticizers [Acetyl Tributyl Citrate (ATBC) and isosorbide diester (ISE)] at three different contents (15 wt %, 20 wt % and 30 wt %) were produced by extrusion method. Thermal, morphological, mechanical and wettability behavior of produced materials was investigated as a function of plasticizer content. Filmature parameters were also adjusted and optimized for different formulations, in order to obtain similar thickness for different systems. Differential scanning calorimeter (DSC) results and evaluation of solubility parameter confirmed that similar miscibility was obtained for ATBC and ISE in PLA, while the two selected plasticizers resulted as not efficient for plasticization of PBS, to the limit that the PBS-30ATBC resulted as not processable. On the basis of these results, isosorbide-based plasticizer was considered a suitable agent for modification of a selected blend (PLA/PBS 80:20) and two mixing approaches were used to identify the role of ISE in the plasticization process: results from mechanical analysis confirmed that both produced PLA-PBS blends (PLA85-ISE15)-PBS20 and (PLA80-PBS20)-ISE15 could guarantee advantages in terms of deformability, with respect to the PLA80-PBS20 reference film, suggesting that the promising use of these stretchable PLA-PBS based films plasticized with isosorbide can provide novel solutions for food packaging applications.
A Control-Plane Perspective on Reducing Data Access Latency in LTE Networks (2017)

Control-plane operations are indispensable to providing data access to mobile devices in the 4G LTE networks. They provision necessary control states at the device and network nodes to enable data access. However, the current design may suffer from long data access latency even under good radio conditions. The fundamental problem is that, data-plane packet delivery cannot start or resume until all control-plane procedures are completed, and these control procedures run sequentially by design. We show both are more than necessary under popular use cases. We design DPCM, which reduces data access latency through parallel processing approaches and exploiting device-side state replica. We implement DPCM and validate its effectiveness with extensive evaluations.
A simple model for the effect of normalization on the convergence rate of adaptive filters (2004)

We propose a new simple model for the input regressor vectors in adaptive filters. This model allows more insight on the effect of normalization on the convergence rate and eigenvalue spread for the normalized least-mean-squares algorithm (NLMS). Using the new model, we show that NLMS works best to reduce eigenvalue spread when the input regressor vector points to all directions with equal probability, but with direction-dependent power.
Toll-like receptor (TLR) polymorphisms in African children: CommonTLR-4variants predispose to severe malaria (2005)

Genetic host factors play a substantial role in susceptibility to and severity of malaria, which continues to cause at least one million deaths per year. Recently, members of the toll-like receptor (TLR) family have been shown to be involved in recognition of the etiologic organism Plasmodium falciparum: The glycosylphosphatidylinositol anchor induces signaling in host cells via TLR-2 and -4, whereas hemozoin-induced immune activation involves TLR-9. Binding of microbial ligands to the respective TLRs triggers the release of proinflammatory cytokines via the TLR/IL-1 receptor (TIR) domain and may contribute to the host response in malaria, including cytokine induction and fever. In a case-control study among 870 Ghanaian children, we examined the influence of TLR-2, -4, and -9 polymorphisms in susceptibility to severe malaria. TLR-2 variants common in Caucasians and Asians were completely absent. However, we found a rare previously undescribed mutation (Leu658Pro), which impairs signaling via TLR-2. We failed to detect any polymorphisms within the TLR-9 Toll/IL-1 receptor domain. Two frequent TLR-9 promoter polymorphisms did not show a clear association with malaria severity. In contrast, the TLR-4-Asp299Gly variant occurred at a high rate of 17.6% in healthy controls and was even more frequent in severe malaria patients (24.1%, P < 0.05). Likewise, TLR-4-Thr399Ile was seen in 2.4% of healthy children and in 6.2% of patients (P = 0.02). TLR-4-Asp299Gly and TLR-4-Thr399Ile conferred 1.5- and 2.6-fold increased risks of severe malaria, respectively. These findings suggest TLR4-mediated responses to malaria in vivo and TLR-4 polymorphisms to be associated with disease manifestation.
Mutational spectrum of type I collagen genes in Korean patients with osteogenesis imperfecta (2006)

Mutations in the type I collagen genes COL1A1 and COL1A2 are responsible for the dominantly inherited connective tissue disorder osteogenesis imperfecta (OI). The severity of OI is diverse, ranging from perinatal lethality to a very mild phenotype that is characterized by normal stature and the absence of deformities. Although there have been several studies on the mutational spectra of COL1A1 and/or COL1A2 in Western populations, very few cases have been reported from Asia. In this study, we investigated 67 unrelated Korean probands with OI and used nucleotide sequence analysis to detect COL1A1 and COL1A2 mutations. Thirty-five different mutations were identified in the two genes, including 24 novel mutations. Among the 35 kinds of detected mutations, 15 were glycine substitutions (seven in COL1A1 and eight in COL1A2), one was a nonsense mutation, four were frameshift mutations in COL1A1, three were in-frame duplications in COL1A2, and 12 were splice site mutations (seven in COL1A1 and five in COL1A2). Until now, mutations in the COL1A1 and COL1A2 genes known to cause OI were unique and rarely repeated in other families. Interestingly, the c.982G>A (p.Gly328Ser) mutation in COL1A2 was found recurrently and was the causative mutation in five independent OI probands. Haplotype analysis of the COL1A2 gene revealed that four probands from five independent OI probands with c.982G>A (p.Gly328Ser) had a common haplotype. Our clinical data showed the heterogeneity even within a specific genotype, which suggested the complex expression of this disease.
Mitigating the effects of chaff in ballistic missile defense (2004)

In this paper, an algorithmic (schema) approach for detecting and tracking targets in highly cluttered environments is presented. The approach is to accurately track the centroid of the chaff cloud using a combination of medium band (MB) and wide band (WB) range resolution radar waveforms. At moderate pulse repetition frequencies (PRFs), differential target velocities (about the centroid of the chaff cloud) are detected and tracked via Doppler banks of transversal filters that are tuned to detect the target velocity differences. Through sensitivity analysis using Matlab models, the theoretical lower bound on detectable differential target velocity as a function of the chaff cloud composition (e.g., clutter cross section, clutter spectral width, number of dipoles, and clutter velocity standard deviation) and radar related parameters (e.g., waveform frequency, bandwidth, integration times, PRFs, and signal-to-clutter ratio) is presented.
Supplementary References from MicroRNA-616 Induces Androgen-Independent Growth of Prostate Cancer Cells by Suppressing Expression of Tissue Factor Pathway Inhibitor TFPI-2 (2023)

Supplementary References from MicroRNA-616 Induces Androgen-Independent Growth of Prostate Cancer Cells by Suppressing Expression of Tissue Factor Pathway Inhibitor TFPI-2
Supplementary Table from Regulation of leukemic cell differentiation and retinoid-induced gene expression by statins (2023)

Supplementary Table from Regulation of leukemic cell differentiation and retinoid-induced gene expression by statins
An elbow biomechanical model and its coefficients adjustment (2014)

Through the establishment of the elbow biomechanical model, it can provide theoretical guide for rehabilitation therapy on the upper limb of the human body. A biomechanical model of the elbow joint can be built by the connection of muscle force model and elbow dynamics. But there are many undetermined coefficients in the model like the optimal joint angle and optimal muscle force which are usually specified as the experimental parameters of other workers. Because of the individual differences, there is a certain deviation of the final result. To this end, the RMS value of the deviation between the actual angle and calculated angle is considered. A set of coefficients which lead to the minimum RMS value will be chosen to be the optimal parameters. The direct search method and the conjugacy search method are used to get the optimal parameters, thus the model can be more accurate and mode adaptability.
An Ireland-Claisen Rearrangement/Lactonisation Cascade as a Key Step in Studies Towards the Synthesis of (-)-Euonyminol: (2011)

Progress towards the asymmetric total synthesis of (-)-euonyminol is described with the focus on the installation of the ­oxygenation pattern on the lower rim of the molecule. An Ireland-Claisen rearrangement/lactonisation cascade has been developed and studies towards further elaboration have uncovered an intriguing tunable diastereoselective α-bromination of the resulting γ-lactone.
The Epidemiology of Adult ADHD (2008)

Until recently, little was known about the epidemiology of attention-deficit/hyperactivity disorder (ADHD) in adults. Bottom-up studies following children with ADHD into adolescence had shown variable rates of persistence, some of which depended on the definitions used. The traditional diagnosis was complicated by the introduction of the Diagnostic and Statistical Manual of Mental Disorders, Third Edition , which stated that ADHD could be diagnosed with inattentive symptoms alone. This resulted in diagnostic inconsistency as earlier investigations demanded the presence of hyperactivity while others did not. Diagnosis also depended on the site, the cohort, whether interviews versus rating scales were employed, and whether the subject or their parent were the source of information.
Diversity of Endophytic Fungi Isolated from Pinus densiflora and Juniperus rigida Distributed in Mt. Baekryeonsan and Mt. Johangsan, Korea (2018)

We investigated the biodiversity of endophytic fungi in Pinus densiflora and Junipreus rigida from Mt. Baekryeonsan and Mt. Johangsan in Korea. In total, 59 isolates were discovered from 26 host plants and identified using sequences from the rDNA internal transcribed spacer (ITS) region. Twenty taxa of endophytic fungi were identified in this study; 62% of isolates belonged to Leotiomycetes, 34% belonged to Sordariomyetes, and 4% belonged to Agaricomycetes. Results confirmed three previously unreported endophytic fungi in Korea: Phanerochaete concrescens, Creosphaeria sassafras, and Scopuloides rimosa. Community analysis showed that the fungal diversity patterns of the samples from Mt Baekryeonsan and Mt. Johangsan are similar to those from previous studies and varied depending upon host and locality.
Composition from fast neutrons: Application to the Moon (2001)

Planetary neutron leakage fluxes provide a measure of surface composition. However to be used in geological studies, a quantitative relationship between measured fluxes and surface composition is needed. The present work shows that neutron production is expected to be a function of the atomic mass, and that the fast leakage flux in the energy range between 0.6 and 8 MeV is linearly related to the average soil atomic mass. This result is consistent with laboratory measurements, and with Lunar Prospector observations of the Moon. When calibrated with returned lunar samples, this relationship is used to construct a map of the average atomic mass of lunar soils.
Light‐Activated Electron Transfer and Catalytic Mechanism of Carnitine Oxidation by Rieske‐Type Oxygenase from Human Microbiota (2020)

Abstract Oxidation of quaternary ammonium substrate, carnitine by non‐heme iron containing Acinetobacter baumannii (Ab) oxygenase CntA/reductase CntB is implicated in the onset of human cardiovascular disease. Herein, we develop a blue‐light (365 nm) activation of NADH coupled to electron paramagnetic resonance (EPR) measurements to study electron transfer from the excited state of NADH to the oxidized, Rieske‐type, [2Fe‐2S] 2+ cluster in the AbCntA oxygenase domain with and without the substrate, carnitine. Further electron transfer from one‐electron reduced, Rieske‐type [2Fe‐2S] 1+ center in AbCntA‐WT to the mono‐nuclear, non‐heme iron center through the bridging glutamate E205 and subsequent catalysis occurs only in the presence of carnitine. The electron transfer process in the AbCntA‐E205A mutant is severely affected, which likely accounts for the significant loss of catalytic activity in the AbCntA‐E205A mutant. The NADH photo‐activation coupled with EPR is broadly applicable to trap reactive intermediates at low temperature and creates a new method to characterize elusive intermediates in multiple redox‐centre containing proteins.