gebhart/patrepeval huggingface dataset:
Early Studies on Protoplast Isolation of Ludisia discolor, A Wild Orchid (2016)

The terrestrial <i>Ludisia discolor</i>, also referred to as the jewel orchid is prized for the quality of its leaves. <i>L. discolor</i> is known as a medicinal herb and is touted for its heat- and pathogen-resisting qualities. <i>L. discolor</i> is valuable in the production of both flavonoids and anthocyanins, antioxidants that are exalted in the health industry. Plant cell cultures have emerged as alternative sources of anthocyanin production. Plant protoplast cultures are used frequently in transient gene expression studies and in the establishment of callus and cell suspension cultures. Benefits of plant protoplast system include similarity to cells found in plant tissues, reproduction under controlled conditions, and prevention of masking of stress responses to previous handling techniques. A study was conducted to assess the amenability of the stem and leaves of <i>L. discolor</i> to protoplast isolation. The stem and leaf segments were weighed, sliced into thin layers, immersed in a digestion medium, washed and then cultured onto a recovery medium. Results indicated that the production of plant protoplasts from <i>L. discolor</i> may be viewed as an alternative in the generation of cell cultures and ultimately in the production of anthocyanins from the cell cultures.
MPEG-I Coding performance in Immersive VR/AR applications (2018)

International audience
Hepatic Venous Congestion After Right-lobe Living-donor Liver Transplantation (2007)

A hypoattenuating area of the liver during DP scans indicates severe hepatic congestion and is correlated with hyperbilirubinemia and a high mortality rate.
Identifier-Locator Network Protocol (ILNP) Engineering Considerations (2012)

This document describes common (i.e., version independent) engineering details for the Identifier-Locator Network Protocol (ILNP), which is an experimental, evolutionary enhancement to IP. This document is a product of the IRTF Routing Research Group.
Fatty Acid Profile and Oil Yield in Six Different Varieties of Fresh and Dry Samples of Coconuts (Cocos nucifera) (2006)

The physical and chemical properties of the oil extracted from six (6) varieties of coconut fruits were determined. The oils were brownish, some yellowish when melted, and at times white when solidified. The oils had specific gravity ranging between 0.90 and 0.92. The yield of the oil (% contents) from the ether extract was also analyzed using soxhlet extraction technique. The results showed the oil contents of 88.54% in dry samples and 69.14% in fresh samples. Result of the findings showed a higher percentage of saturated fatty acid content across the entire samples (88.5±0.85% 97.0±0.37%) in the dry samples, than the unsaturated fatty acid constituents (8.4±0.45% 9.5±0.30%). The moisture content was higher in the fresh samples than the dry samples. These findings therefore suggest a high percentage oil yield in the dry samples. It is therefore advisable that the nuts be harvested dry if the oil is intended for commercial use.
Sequestosome 1/p62: across diseases (2012)

Sequestosome 1/p62 is a signal modulator or adaptor protein involved in receptor-mediated signal transduction. Sequestosome 1/p62 is gaining attention as it is involved in several diseases including Parkinson disease, Alzheimer disease, liver and breast cancer, Paget's disease of bone, obesity and insulin resistance. In this review, we will focus on the most recent advances on the physiological function of p62 relevant to human diseases.
Hepatocyte growth factor and keratinocyte growth factor regulation of epithelial and stromal corneal wound healing (2005)

Hepatocyte growth factor and KGF appeared to have potent and often opposite effects on epithelial and stromal cells following a wound. Hepatocyte growth factor was more detrimental than KGF, resulting in an aberrant epithelium and mass differentiation of keratocytes into myofibroblasts. Inhibition of HGF may be an appropriate therapeutic intervention in the case of persistent epithelial defects and to prevent fibrosis following a corneal stromal wound such as can occur after refractive surgery.
Evaluation of Mechanistic-Empirical Performance Prediction Models for Flexible Pavements (1998)

In recognition of the potential of mechanistic-empirical (M-E) methods in analyzing pavements and predicting their performance, pavement engineers around the country have been advocating the movement toward M-E design methods. In fact, the next AASHTO Guide for Design of Pavement Structures is planned to be mechanistically based. Since many of the performance models used in the M-E methods are laboratory-derived, it is important to validate these models using data from in-service pavements. The Long-Term Pavement Performance (LTPP) program data provide the means to evaluate and improve these models. The fatigue and rutting performances of LTPP flexible pavements were predicted using some well-known M-E models, given the loading and environmental conditions of these pavements. The predicted performances were then compared with actual fatigue cracking and rutting observed in these pavements. Although more data are required to arrive at a more conclusive evaluation, fatigue cracking models appeared to be consistent with observations, whereas rutting models showed poor agreement with the observed rutting. Continuous functions that relate fatigue cracking to fatigue damage were developed.
ChemInform Abstract: AZABENZOCYCLOHEPTENONES PART 18, AMINES AND AMINO‐KETONES OF THE TETRAHYDRO‐3‐BENZAZEPIN‐1‐ONE‐SERIES (1975)

Abstract Das N‐Tosyl‐benzazepinol (I) läßt sich zum Azepinol (IIa) detosylieren, während eine Detosylierung des (I)‐analogen Ketons nicht möglich ist.
Conjugate addition-cycloacylation of acetylenic diesters: synthesis of highly functionalized cyclopentenones (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTConjugate addition-cycloacylation of acetylenic diesters: synthesis of highly functionalized cyclopentenonesMichael T. Crimmins, S. Wayne Mascarella, and Joe A. DeLoachCite this: J. Org. Chem. 1984, 49, 16, 3033–3035Publication Date (Print):August 1, 1984Publication History Published online1 May 2002Published inissue 1 August 1984https://pubs.acs.org/doi/10.1021/jo00190a037https://doi.org/10.1021/jo00190a037research-articleACS PublicationsRequest reuse permissionsArticle Views526Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
HLA-A*24:07 as a Potential Biomarker for Carbamazepine-Induced Stevens–Johnson Syndrome/Toxic Epidermal Necrolysis in Filipino Patients (2021)

<b>Aim:</b> A case-control study was conducted in Filipino patients to determine the association between HLA alleles and carbamazepine-induced Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN). <b>Materials & methods:</b> A retrospective review of medical records and data collection were performed. A total of 10 carbamazepine-induced SJS/TEN cases and 40 tolerant controls were recruited. Genomic DNA extracted from saliva samples was genotyped. Statistical analysis was done. <b>Results:</b> The HLA-B75 serotype (p = 0.003; odds ratio [OR] = 13.8; 95% CI = 2.5-76.8), <i>HLA-B*15:21</i> (p = 0.041; OR = 4.7; 95% CI = 1.1-20.8) and <i>HLA-A*24:07</i> (p = 0.032; OR = 6; 95% CI = 1.2-30.7) were significantly associated with carbamazepine-induced SJS/TEN. <b>Conclusion:</b> The HLA-B75 serotype, <i>HLA-B*15:21</i> or <i>HLA-A*24:07</i> may be used for pharmacogenetic screening prior to prescribing carbamazepine in Filipinos.
Heat shock and arsenite increase expression of the multidrug resistance (MDR1) gene in human renal carcinoma cells. (1990)

The multidrug transporter, initially identified as a multidrug efflux pump responsible for resistance of cultured cells to natural product cytotoxic drugs, is normally expressed on the apical membranes of excretory epithelial cells in the liver, kidney, and intestine. This localization suggests that the multidrug transporter may have a normal physiological role in transporting cytotoxic compounds or metabolites. In the liver, hepatectomy or treatment with chemical carcinogens increases expression of the MDR1 gene which encodes the multidrug transporter. To evaluate conditions which increase MDR1 gene expression, we have investigated the induction of the MDR1 gene by physical and chemical environmental insults in the renal adenocarcinoma cell line HTB-46. There are two strong heat shock consensus elements in the major MDR1 gene promoter. Exposure of HTB-46 cells to heat shock, sodium arsenite, or cadmium chloride led to a 7- to 8-fold increase in MDR1 mRNA levels. MDR1 RNA levels did not change following glucose starvation or treatment with 2-deoxyglucose and the calcium ionophore A23187, conditions which are known to activate the expression of another family of stress proteins, the glucose-regulated proteins. The levels of the multidrug transporter, P-glycoprotein, as measured by immunoprecipitation, were also increased after heat shock and sodium arsenite treatment. This increase in the level of the multidrug transporter in HTB-46 cells correlated with a transient increase in resistance to vinblastine following heat shock and arsenite treatment. These results suggest that the MDR1 gene is regulatable by environmental stress.
Comparison of Process Options for Improving Backend-of-Line Reliability in 28 nm Node Technologies and Beyond (2011)

This paper compares the most encouraging process options for improving electromigration performance in advanced technology nodes. Metal capping yields the best electromigration performance; however, this process is most challenging with respect to integration and may also suffer from significantly decreasing grain sizes in trench bottoms for future technologies. Alloying or silicidation techniques are less challenging to implement but can result in unacceptably high resistance increases. We analyze the respective results for each option and compare the performance on 45, 32, and 28 nm technology nodes. In addition, the impact of the various process options on stressmigration and time-dependent dielectric breakdown are discussed.
Genetic analysis of plasmid determinants for microcin J25 production and immunity (1996)

Microcin J25 (MccJ25) is a small peptide antibiotic produced by an Escherichia coli strain isolated from human feces. The genetic determinants for MccJ25 synthesis and immunity have been cloned from the low-copy-number wild-type plasmid pTUC1OO into the compatible vectors pBR322 and pACYC184. Physical and phenotypical analysis of insertion mutations and complementation tests defined three contiguous genes involved in MccJ25 production which span a region of about 2.2 kb. Immunity to the antibiotic is provided by an additional gene adjacent to the production region.
Facile one-step sonochemical synthesis of ultrafine and stable fluorescent C-dots (2015)

This work describes a one-step synthesis of carbon dots (C-dots), which is carried out by sonication of polyethylene glycol (PEG-400) for 0.5-3h. The effect of the various experimental parameters, such as sonication time, amplitude and temperature on the size and the fluorescence of the C-dots was studied. It was found that the average diameter of the C-dots is between 2 and 9 nm, depending on the preparation conditions. The highest quantum yield of emission was ∼ 16%. These high fluorescence properties of the C-dots could be used for bioimaging and for solar cell applications.
Use of 1-Methylcyclopropene in Ornamentals: Carnations as a Model System for Understanding Mode of Action (2008)

The first commercial use of 1-methylcyclopropene (1-MCP) was with cut flowers and potted plants, and treatment with this compound is still the preferred strategy for protection of most ethylene-sensitive crops. Research is continuing into optimum treatment conditions and strategies for efficient application in commerce. In studies using carnation ( Dianthus caryophyllus L. ‘White Sim’) petals to determine the optimal conditions for commercial treatment, we noted some aspects of the inhibition response that were not consistent with the current competitive inhibition model of 1-MCP action. Our data are better explained by an alternative model in which 1-MCP binds to a site that is exposed during the allosteric changes that accompany the enzymatic activities of the binding site in the absence of ethylene.
Cross-layer admission control based on service upgrading/degrading in CDMA systems with successive interference cancellation (2010)

In CDMA systems with successive interference cancellation (SIC), conflicting quality of service (QoS) requirements at different protocol layers must be traded off carefully when designing the admission control (AC) policy at the network layer, especially, the adjustment of decoding orders at the physical layer should be taken into account, and thus the cross-layer AC needs to be considered. Moreover, due to the elastic traffic characteristic of data services, the service level of this kind of users can be upgraded or degraded according to the situation of system load such that the overall system performance will be improved. In this paper, we study the AC policy in CDMA systems with SIC and propose a cross-layer AC algorithm based on service upgrading/degrading, where the aspects of the power constraint and decoding order adjustment at the physical layer are taken into account. We conduct extensive simulation experiments, and the numerical results demonstrate that by our proposed algorithm, the overall system performance such as throughput will be increased meanwhile more users can be admitted into the system.
Randomized Caching in Cooperative UAV-Enabled Fog-RAN (2019)

We consider an unmanned aerial vehicle enabled (UAV-enabled) fog-radio access network (F-RAN) in which UAVs are considered as flying remote radio heads (RRH) equipped with caching and cooperative communications capabilities. We are mainly focus on probabilistic/randomized content placement strategy, and accordingly formulate the content placement as an optimization problem. We then study the efficiency of the proposed content placement by evaluating the average system capacity and its energy-efficiency. Our results indicate that cooperative communication plays an essential role in UAVenabled edge communications as it effectively curbs the impact of dominant Line-of-Sight (LOS) received interference. It is also seen that cooperative cache-enabled UAV F-RAN performs better in high-rise environments than dense urban and sub-urban environments. This is due to a significant reduction of the received LOS interference because of blockage by the high-rise buildings, and the performance gain of cooperative communication on the attending signal. Comparing the performances of the developed content placement strategy and conventional caching techniques shows that our proposed probabilistic/randomized caching outperforms the others in most of the practical cases.
RHEB cancer expression and clinico-pathological data from Mammalian Target of Rapamycin Activator RHEB Is Frequently Overexpressed in Human Carcinomas and Is Critical and Sufficient for Skin Epithelial Carcinogenesis (2023)

RHEB cancer expression and clinico-pathological data from Mammalian Target of Rapamycin Activator RHEB Is Frequently Overexpressed in Human Carcinomas and Is Critical and Sufficient for Skin Epithelial Carcinogenesis
Mobile app for image based bill data processing (2013)

Bill payment is a part of mobile banking solution provided by banks to its consumers. Traditionally biller data and payment details are entered manually by the consumer on banking application. We have ideated and prototyped a mobile based application for reading bill related details from their image data. Image data is captured using the mobile based application which is cleaned and converted to structured bill data. This structured data which is otherwise entered manually by consumer is automatically extracted and sent to banking systems for bill processing. This opens several new avenues for bill data analytics at financial institutions. We have developed a computer vision based application on a smart phone and evaluated it on real utility bill data.
Sub-Terahertz Performance for Beyond 5G in Indoor Environments (2022)

THz and sub-THz (100-300GHz) communications are prospective technologies discussed for beyond 5G and 6G networks. At these frequencies, some of the main challenges are its propagation conditions (e.g., high molecular absorption and poor diffraction), and the limited coverage due to limited transmit power in combination with wide bandwidths. This paper evaluates coverage, available bitrates and capacity of an indoor network using 100 GHz carrier frequency. The conclusion is that THz bands are an alternative to support indoor scenarios in the 6G timeframe.
Translational Induction of Liver-enriched Transcriptional Inhibitory Protein during Acute Phase Response Leads to Repression of CCAAT/Enhancer Binding Protein α mRNA (2000)

Lipopolysacharide (LPS) induced acute phase response (APR) in mouse liver leads to elevation of the low molecular weight CCAAT/Enhancer binding protein (C/EBP) β isoform, liver-enriched transcriptional inhibitory protein (LIP). In this paper, we investigate the pathway for LIP induction during APR and the role of LIP in regulation of the C/EBPα promoter. The 5′ region of C/EBPβ mRNA has been shown to be involved in the regulation of LIP translation. Our data demonstrate that binding of cytoplasmic proteins to the 5′ region of C/EBPβ mRNA is altered in response to LPS administration. One of the major changes is induced binding of a cytoplasmic protein that is immunologically identical to the previously characterized RNA-binding protein CUGBP1. Induction of CUGBP1 binding activity in liver cytoplasm during APR is accompanied by the elevation of CUGBP1 binding activity on polysomes. CUGBP1 immunoprecipitated from livers of LPS-treated mice, but not from normal animals, is capable of inducing LIP translation in a cell-free translation system. The ability of CUGBP1 to induce LIP translation during APR depends on phosphorylation of CUGBP1. We show that elevation of LIP during APR and after partial hepatectomy leads to increased binding of LIP to the C/EBP consensus site found within the mouse C/EBPα promoter. This binding correlates with reduction of C/EBPα mRNA levels in both biological situations. Co-transfection experiments showed that full-length C/EBPβ activates the C/EBPα promoter, while LIP blocks this activation. Our data suggest that the dominant negative isoform of C/EBPβ, LIP, down-regulates the C/EBPα promoter in liver and in cultured hepatocytes. Because full-length C/EBPα and C/EBPβ proteins regulate liver proliferation, this function of LIP may be important in liver growth and differentiation.
Un centurion tueur et voyeur (2014)

Le texte à étudier est une inscription qui a été trouvée dans un lieu appelé jadis Aquæ Flauianæ, ce qui veut dire « Les sources des Flaviens », les Flaviens étant les empereurs qui ont gouverné l’Empire romain de 69 à 96. Il est intéressant de noter que le nom moderne garde la trace du nom ancien ; en effet, Hr el-Hammam désigne « la ferme (Henchir) qui se trouve près du bain public (Hammam) ». Ce site a peut-être été fondé par l’armée, disons bien : « peut-être » ; il ne faut pas trop prête...
How a virus travels the world (2015)

Wild birds may spread the H5N8 virus
Terrain following and applications:Caenorhabditis elegansswims along the floor using a bump and undulate strategy (2016)

Nematodes such as Caenorhabditis elegans are heavier than water. When submerged in water, they settle to the bottom surface. Observations reveal that the animals do not lie flat on the bottom surface, but remain substantially suspended above the surface through continuous collisions with the surface, while maintaining their swimming gaits. Consequently, the swimming animals follow the bottom surface topography. When the bottom surface is inclined, the animals swim up or down along the incline. As the magnitude of the gravitational force can be easily estimated, this behaviour provides a convenient means to estimate the animal's propulsive thrust. The animals' tendency to follow the surface topography provides a means to control the swimmers' trajectories and direction of motion, which we demonstrate with a saw tooth-like ratchet that biases the animals to swim in a selected direction. The animals can also serve as surface topography probes since their residence time as a function of position provides information on surface features. Finally, we take advantage of surface following to construct a simple motility-based sorter that can sort animals based on genotype and state of health.
Underactuated rotary inverted pendulum control using robust generalized dynamic inversion (2020)

The article applies the robust generalized dynamic inversion control methodology to the problem of stabilizing upright equilibrium configuration of the under-actuated rotary inverted pendulum system while tracking rotary motion of the actuated arm. The proposed robust generalized dynamic inversion control law comprised equivalent and switching control parts. The equivalent control part works to enforce a virtual constraint dynamics of the controlled state variables by means of Moore–Penrose generalized inversion. The switching control part is of the sliding mode type, and it improves robustness against unmodeled system dynamics, parametric uncertainties, and external disturbances. The robust generalized dynamic inversion control design on the linearized model of the under-actuated rotary inverted pendulum is shown to guarantee semi-global asymptotically stable tracking performance. Numerous computer simulations and experiments are conducted on the Quanser rotary inverted pendulum system, revealing that the proposed algorithm has better convergence and tracking performance than conventional sliding mode and generalized dynamic inversion control strategies when both are applied separately.