gebhart/patrepeval huggingface dataset:
Influence of dietary iodine deficiency on the thyroid gland in Slc26a4-null mutant mice (2011)

An iodine-deficient diet did not induce goiter in Slc26a4-null mice, suggesting that other environmental, epigenetic or genetic factors are involved in goiter development in PDS.
Expression of the Cytolethal Distending Toxin (Cdt) Operon in Actinobacillus actinomycetemcomitans: Evidence That the CdtB Protein Is Responsible for G2 Arrest of the Cell Cycle in Human T Cells (2000)

We have previously shown that Actinobacillus actinomycetemcomitans produces an immunosuppressive factor that is encoded by the cdtB gene, which is homologous to a family of cytolethal distending toxins (Cdt) expressed by several gram-negative bacteria. In this study, we report that the cdt locus in A. actinomycetemcomitans is composed of five open reading frames, designated orf1, orf2, cdtA, cdtB, and cdtC. The deduced amino acid sequences of the five open reading frames are highly conserved among A. actinomycetemcomitans strains 652, Y4, 29522, and HK1651. There is also strong homology with the Cdt proteins of Haemophilus ducreyi (87-91%), but only partial homology with that of Campylobacter jejuni and Escherichia coli (29-48%). Analysis of A. actinomycetemcomitans mRNA by RT-PCR suggests that the two small open reading frames upstream of cdtA are coexpressed with cdtA, cdtB, and cdtC. We next utilized a series of plasmids that express various combinations of the cdt genes to determine their requirement for expression of immunoinhibitory activity. Cell extracts of E. coli transformed with each of the plasmids were tested for their capacity to induce G2 arrest in the cell cycle of PHA-activated human T cells. These experiments suggest that expression of cdtB alone is sufficient to induce G2 arrest in human T cells, but do not exclude the possibility that cdtC also contributes to cell cycle arrest. The implications of our results with respect to the function of the individual Cdt proteins are discussed.
A New Control Device for Washing Machines Using a Microcomputer and Detectors (1984)

A new control device using a microcomputer and detectors was developed to reduce both water and electric power consumption in automatic washing machines. The control device adopts the following detectors: a rinsing detector employing two light-emitting diode/photo- transistor assemblies for nieasuring the transmittance of the rinsing water and a load detector employing a rotation detector for measuring a load on a pulsator. These detectors not only measure the rinsing degree and the wash load but also compensate errors and variations in the detected values for accurate measurements. By using this control device, about 20 percent of both electric power and water consumption is saved as well as about 30 percent of the rinsing time. In addition, damage of the washed clothes caused by excessive washing is prevented.
Super-Resolution Characterization of Heterogeneous Light–Matter Interactions between Single Dye Molecules and Plasmonic Nanoparticles (2020)

ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTSuper-Resolution Characterization of Heterogeneous Light–Matter Interactions between Single Dye Molecules and Plasmonic NanoparticlesSaaj ChattopadhyaySaaj ChattopadhyayApplied Physics Program, University of Michigan, Ann Arbor, Michigan 48109, United StatesMore by Saaj ChattopadhyayView Biography and Julie S. Biteen*Julie S. BiteenDepartment of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States*Email: [email protected]More by Julie S. BiteenView Biographyhttp://orcid.org/0000-0003-2038-6484Cite this: Anal. Chem. 2021, 93, 1, 430–444Publication Date (Web):October 26, 2020Publication History Published online26 October 2020Published inissue 12 January 2021https://pubs.acs.org/doi/10.1021/acs.analchem.0c04280https://doi.org/10.1021/acs.analchem.0c04280review-articleACS PublicationsCopyright © 2020 American Chemical SocietyRequest reuse permissionsArticle Views1723Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Dyes and pigments,Fluorescence,Molecules,Plasmonics,Surface plasmon resonance Get e-Alerts
Effect of Targeting Inflammation With Salsalate (2016)

clinicaltrials.gov Identifier: NCT00624923.
Occupancy Visualization towards Activity Recognition (2019)

We present a sensor visualization system that integrates data streams from individual custom sensor arrays together with Building Automation System (BAS) data. To help bridge the gap between actual building usage by the occupants, and the aggregate assumed usage by the control system, we have developed several sensor processing subsystems moving toward automated human activity recognition without the need for directly instrumenting the occupants. By having a system with a detailed understanding of occupancy behavior and needs, we believe buildings could be much more efficient thereby reducing energy consumption, working toward sustainability of the built environment.
Salmon cardiac natriuretic peptide is a volume-regulating hormone (2002)

The present study tested the hypothesis that salmon cardiac peptide (sCP), a new member of the family of natriuretic peptides, has an important role in the regulation of fluid balance and cardiovascular function. Intra-arterial administration of sCP increased urine output in salmon. It had a diuretic effect in rat as well, but the potency was lower. sCP increased the sodium excretion in proportion to the increased urine flow. Blood pressure was not affected by sCP in either species. Acute volume expansion elevated the plasma level of sCP in salmon, and an acute transfer of salmon from fresh to sea water decreased the circulating sCP level. Cardiac immunoreactive sCP or sCP mRNA levels were not affected by transfer to sea water. These results indicate that sCP has an important physiological role in defending salmon against volume overload but that it does not appear to contribute to the short-term regulation of blood pressure. sCP provides an excellent model of the general mechanisms of regulation of the A-type (atrial) natriuretic peptide system.
CMRULES: An Efficient Algorithm for Mining Sequential Rules Common to Several Sequences (2010)

International audience
Circular polarization on depolarizing chipless RFID tags (2016)

We propose a new chipless RFID scheme that relies on circularly polarized waves to provide an alignment-independent chipless RFID solution. This approach not only increases the readability of the tags, but also incorporates depolarization capability, reducing the interference effects produced by changes in the environment. The reading signal is right hand circularly polarized (RHP), while the signal reflected by objects in the environment produce a left-hand circularly polarized (LHP) signal that is rejected by the receiver. The proposed tags reflect a RHP signal that is properly detected.
Système de régulation de pression agissant localement sur la peau et le tissu sous-cutané - System for Adjusting Pressure Locally on the Skin and Subcutaneous Tissue (2015)

Système de régulation de pression agissant localement sur la peau comprenant un ensemble de modules adjacents distribués de manière à former une couche ; chaque module comprenant un coussin déformable comprenant une cavité, une valve, un réservoir et un capteur de pression, la cavité et le réservoir communiquant par le biais de la valve et le capteur étant disposé de manière à capter une pression agissant directement ou indirectement sur le coussin ; le système comprenant en outre une boucle de rétroaction disposée de manière à augmenter ou réduire la déformation du coussin en fonction de la pression détectée par le capteur. Le système selon l’invention peut être intégré dans une chaussure pour rétablir une pression plantaire normale sous toute la plante du pied, ce qui est souhaitable notamment pour des patients souffrants du diabète sucré et de la lèpre ou pour des sportifs. Il est également possible d’intégrer le système selon l’invention dans un matelas (lit ou chaise roulante) pour éviter ainsi des escarres de décubitus chez des patients avec maladies neurologiques (hémiplégie, paraplégie, tétraplégie, sclérose en plaque, sclérose latérale amyotrophique) et toutes autres maladies avec déficits sensitifs et/ou moteurs.
Ripening and dilatation of the unfavourable cervix for induction of labour by a double balloon device: experience with 250 cases (1997)

1. The double balloon device induces significant ripening and dilatation of the unfavourable cervix. 2. Induction of labour was successfully achieved following removal of the Atad Ripener Device. 3. Our caesarean section rate was low compared with rates reported for women with an unfavourable cervix induced by other methods.
Dependence of and field patterns of surface coils on the electrical properties of the sample and the MR operating frequency (2016)

In high field MRI, the spatial distribution of the radiofrequency magnetic ( <b><i>B</i></b><sub>1</sub>) field is usually affected by the presence of the sample. For hardware design and to aid interpretation of experimental results, it is important both to anticipate and to accurately simulate the behavior of these fields. Fields generated by a radiofrequency surface coil were simulated using dyadic Green's functions, or experimentally measured over a range of frequencies inside an object whose electrical properties were varied to illustrate a variety of transmit [Formula: see text] and receive [Formula: see text] field patterns. In this work, we examine how changes in polarization of the field and interference of propagating waves in an object can affect the <b><i>B</i></b><sub>1</sub> spatial distribution. Results are explained conceptually using Maxwell's equations and intuitive illustrations. We demonstrate that the electrical conductivity alters the spatial distribution of distinct polarized components of the field, causing "twisted" transmit and receive field patterns, and asymmetries between [Formula: see text] and [Formula: see text]. Additionally, interference patterns due to wavelength effects are observed at high field in samples with high relative permittivity and near-zero conductivity, but are not present in lossy samples due to the attenuation of propagating EM fields. This work provides a conceptual framework for understanding <b><i>B</i></b><sub>1</sub> spatial distributions for surface coils and can provide guidance for RF engineers.
Masking of unknown output values during output response compression by using comparison units (2004)

A circuit may produce unknown output values during simulation of a test set, e.g., due to an unknown initial state or due to the existence of tristate elements. Unknown output values in the output response of a circuit make it impossible to determine a single unique signature for the fault-free circuit when built-in self-test is used for testing the circuit. We consider the problem of synthesizing a logic block that replaces unknown output values in the output response of a circuit with a known constant. The logic block is constructed from building blocks called comparison units. The synthesis procedure ensures that the built-in self-test scheme will be able to detect all the faults detectable by the test set applied to the circuit while allowing a single unique signature to be computed. Two variations of the synthesis procedure are considered, a two-dimensional version suitable for synchronous sequential circuits without scan and for scan circuits with multiple scan chains and a one-dimensional version suitable for scan circuits with a single scan chain.
The Characteristics of Intravenous Adenosine-Induced Antinociception in a Rabbit Model of Acute Nociceptive Pain: A Comparative Study with Remifentanil (2006)

Remifentanil had a rapid onset and short duration of action, and probably showed signs of tolerance development, whereas the antinocieptive effect of adenosine was slow in onset and long-lasting, despite its ultrashort plasma half-life and the immediate on-off profiles of its vasodilating effect.
Aristotle's Laptop: The Discovery of Our Informational Mind (2012)

Aristotle's convincing philosophy is likely to have shaped (even indirectly) many of our current beliefs, prejudices and attitudes to life. This includes the way in which our mind (that is, our capacity to have private thoughts) appears to elude a scientific description. This book is about a scientific ingredient that was not available to Aristotle: the science of information. Would the course of the philosophy of the mind have been different had Aristotle pronounced that the matter of mind was information? This "mind is information" assertion is often heard in contemporary debates, and this book explores the verities and falsehoods of this proposition
On Imitation Learning of Linear Control Policies: Enforcing Stability and Robustness Constraints via LMI Conditions (2021)

When applying imitation learning techniques to fit a policy from expert demonstrations, one can take advantage of prior stability/robustness assumptions on the expert's policy and incorporate such control-theoretic prior knowledge explicitly into the learning process. In this paper, we formulate the imitation learning of linear policies as a constrained optimization problem, and present efficient methods which can be used to enforce stability and robustness constraints during the learning processes. Specifically, we show that one can guarantee the closed-loop stability and robustness by posing linear matrix inequality (LMI) constraints on the fitted policy. Then both the projected gradient descent method and the alternating direction method of multipliers (ADMM) method can be applied to solve the resulting constrained policy fitting problem. Finally, we provide numerical results to demonstrate the effectiveness of our methods in producing linear polices with various stability and robustness guarantees.
Diminishing Efficacy of Prone Positioning With Late Application in Evolving Lung Injury (2021)

The effects of prone positioning on lung aeration may depend on the stage of lung injury and duration of prior ventilation; this may limit the clinical efficacy of this treatment if applied late.
Combined Radiotherapeutic and Surgical Management of a Spinal Cord Compression by Extramedullary Hematopoiesis in a Patient with Hemoglobin E Beta-Thalassemia (1994)

A 22-year-old male with a history of hemoglobin E beta zero-thalassemia presented with thoracic spinal cord compression due to extramedullary hematopoietic tissue in the epidural space. Following decompressive laminectomy, this epidural mass was irradiated to 20.4 Gy in 12 fractions. The patient made a complete recovery from his neurological symptoms following treatment. Follow-up radiographs showed significant reductions in size of the extradural tumor. Results from this case supported by review of the literature suggest that radiation therapy, with or without decompressive surgery, is an effective therapy in treatment of patients with spinal cord compression due to epidural extramedullary hematopoietic tissue.
Cooperative detection for falsification and isolation of malicious nodes for wireless sensor networks in open environment (2017)

In wireless sensor networks, physical contact to sensor nodes by outsiders must be considered, because wireless sensor networks will be deployed in open environments that are populated by outsiders. Malicious outsiders can access a sensor node's storage and steal such security-related information as a key and inject malicious sensor nodes that can pass through authentication using that stolen key and perform falsifications in networks. The conventional schemes for falsification detection generally use a digital signature; however, these techniques require a completely secure key. Therefore, they cannot effectively work in situations when the key is not secure, and the reliability of the data is completely lost. Accordingly, in this paper, to protect the reliability of wireless sensor networks without a secure key, we propose a mechanism that detects malicious nodes by the cooperation of proper nodes and logically isolate the detected, malicious nodes from wireless sensor networks.
The Druggable Genome: Evaluation of Drug Targets in Clinical Trials Suggests Major Shifts in Molecular Class and Indication (2013)

The largest innovations within pharmaceutical development come through new compounds that have unique and novel modes of action. These innovations commonly involve expanding the protein space targeted by pharmaceutical agents. At present, information about drugs and drug targets is available online via public databases such as DrugBank and the Therapeutic Targets Database. However, this information is biased, understandably so, toward established drugs and drug-target interactions. To gain a better overview of the drug-targeted portion of the human proteome and the directions of current drug development, we developed a data set of clinical trial drug-target interactions based on CenterWatch's Drugs in Clinical Trials Database, one of the largest databases of its kind. Our curation identified 475 potentially novel clinical trial drug targets. This review aims to identify trends in drug development based on the potentially novel targets currently being explored in clinical trials.
Consumption Profile of Preschool Children Supplemented with Different Dosages of Red Palm Oil, Retinol Palmitate and Groundnut Oil (2001)

Acceptability of red palm oil-incorporated food supplements among preschool children have been established through field trials in India and elsewhere. The importance of RPO supplementation among preschool children acquired much significance due to its richness in β-carotene, a precursor of vitamin A. Supplementation of β-carotene through RPO for enhancing vitamin A status and preventing vitamin A deficiency, apart from re-establishing the oil's acceptability has been reported.
Hemangiomas infantiles tratados con aplicación secuencial de láser de colorante pulsado y Nd:YAG: estudio retrospectivo (2013)

We believe that treatment with dual-wavelength light from a pulsed dye laser and a Nd:YAG laser is a viable treatment option for infantile hemangiomas when first-line therapies are ineffective or contraindicated.
Intravenous Versus Intracoronary Myocardial Contrast Echocardiography for Evaluation of No‐Reflow After Primary Percutaneous Coronary Intervention (2005)

IV-MCE at D2 might be substituted for IC-MCE performed immediately after PCI for the evaluation of no-reflow and prediction of left ventricular systolic function after 1 month in patients with anterior wall AMI.
Highly Porous Carbons Synthesized from Tannic Acid via a Combined Mechanochemical Salt-Templating and Mild Activation Strategy (2021)

Highly porous activated carbons were synthesized via the mechanochemical salt-templating method using both sustainable precursors and sustainable chemical activators. Tannic acid is a polyphenolic compound derived from biomass, which, together with urea, can serve as a low-cost, environmentally friendly precursor for the preparation of efficient N-doped carbons. The use of various organic and inorganic salts as activating agents afforded carbons with diverse structural and physicochemical characteristics, e.g., their specific surface areas ranged from 1190 m<sup>2</sup>·g<sup>-1</sup> to 3060 m<sup>2</sup>·g<sup>-1</sup>. Coupling the salt-templating method and chemical activation with potassium oxalate appeared to be an efficient strategy for the synthesis of a highly porous carbon with a specific surface area of 3060 m<sup>2</sup>·g<sup>-1</sup>, a large total pore volume of 3.07 cm<sup>3</sup>·g<sup>-1</sup> and high H<sub>2</sub> and CO<sub>2</sub> adsorption capacities of 13.2 mmol·g<sup>-1</sup> at -196 °C and 4.7 mmol·g<sup>-1</sup> at 0 °C, respectively. The most microporous carbon from the series exhibited a CO<sub>2</sub> uptake capacity as high as 6.4 mmol·g<sup>-1</sup> at 1 bar and 0 °C. Moreover, these samples showed exceptionally high thermal stability. Such activated carbons obtained from readily available sustainable precursors and activators are attractive for several applications in adsorption and catalysis.
Comparative study of the nematic phase-isotropic phase transition in systems of uniaxial hard cores (1989)

We apply the smoothed density approximation to study the nematic phase-isotropic phase transition (N-I) for the following systems: hard ellipsoids of revolution (HE), hard spherocylinders (HSC), and cylinders (HC). We find that the transition is very sensitive to the shape of the hard core modelling a liquid crystal molecule. In the case of HC, the nematic phase can exist in the whole range of elongations x, while for HE and HSC the nematic density at the transition exceeds the close packing density in some range of x, around x = 1. Also the dependence on x of the nematic order parameter, Q, the density, Δη, and entropy, ΔS, jumps at N–I transition is completely different for HC in comparison to HE and HSC.
Photovoltaic materials and manufacturing issues : symposium held December 2-4, 2008, Boston, Massachusetts, U.S.A. (2009)

Manufacturing and sales of photovoltaic (PV) energy have been growing at rates in excess of 40% for the last several years. Advances in materials research have been the basis for much of this progress - resulting in reduced costs and improved conversion efficiencies and reliabilities for solar systems. This volume features studies from a cross-section of current industry research leaders, new start-up companies, and university and laboratory researchers. It highlights the most significant advances in PV materials and device research, and examines research challenges to reaching the ultimate potential of current-generation (crystalline silicon), next-generation (thin films and concentrators), and future-generation PV technologies. The latter includes innovative materials and device concepts that hold the promise of significantly higher conversion efficiencies and/or much lower costs. Topics include: silicon solar cells and devices; thin-film polycrystalline materials and devices; characterization and new technologies.
SYNTHESIS OF SOME NEW 2,6-DIAMINO-4-(P-ARYLAZO) ANILINOPYRIMIDINE AND SOME RELATED 5-ARYLAZOPYRIMIDINE DERIVATIVES FOR DYEING SYNTHETIC FIBRES (2001)

Article SYNTHESIS OF SOME NEW 2,6-DIAMINO-4-(P-ARYLAZO) ANILINOPYRIMIDINE AND SOME RELATED 5-ARYLAZOPYRIMIDINE DERIVATIVES FOR DYEING SYNTHETIC FIBRES was published on June 1, 2001 in the journal Heterocyclic Communications (volume 7, issue 3).