gebhart/patrepeval huggingface dataset:
Security Proof for Partial-Domain Hash Signature Schemes (2002)

Abstract. We study the security of partial-domain hash signature schemes, in which the output size of the hash function is only a fraction of the modulus size. We show that for e = 2 (Rabin), partial-domain hash signature schemes are provably secure in the random oracle model, if the output size of the hash function is larger than 2/3 of the modulus size. This provides a security proof for a variant of the signature standards ISO 9796-2 and PKCS#1 v1.5, in which a larger digest size is used.
Editorial Comment (2004)

This year’s symposium of Proceedings of the Hip Society contains a diverse cross section of topics regarding hip surgery. The variety of subject matter is due to the excellent organization of William Maloney, MD who served as Program Chairman for the 2004 Open Scientific Meeting of the Hip Society held in San Francisco in March. This collection of papers clearly shows that the ongoing investigations and efforts of the Hip Society represent far more than just total hip arthroplasty. Nonarthroplasty themes include arthroscopic treatment of the hip, magnetic resonance imaging of hip pathology, core decompression for osteonecrosis, femoro-acetabular impingement, and acetabular osteotomy. Arthroplasty of the hip for intertrochanteric or femoral neck fractures, osteonecrosis, and severe bone loss of the acetabulum or femur also are covered. The use of larger femoral heads and the current knowledge regarding alternative bearing surfaces also are included. The emerging issue of minimally invasive surgical techniques represents a new area for primary hip surgery. The award papers are equally diverse and cover issues such as the development of a bioactive implant surface directed against infection, the role of tribology in total joint replacement, and importantly, the early clinical results of highly cross-linked polyethylene. The classic paper by Gibson was selected because of the recent increased interest in new surgical approaches and to remind us of the need to review critically the original literature and be cognizant of being specific about that literature. For several generations of orthopaedic surgeons, the Gibson approach consistently has been referred to as a posterior hip approach. In fact, this paper describes a combined anterior and posterior surgical approach to the hip joint depending on what feature of the approach is emphasized. This approach describes a posterior skin incision with anterior and posterior release of musculature from the femur followed by hip dislocation consistent with an anterior surgical approach. As new surgical approaches are described with multiple or percutaneous incisions, some with in situ femoral head resection and no hip dislocation, the need for precise nomenclature and communication about these new surgical approaches to the hip joint becomes increasingly important. The breadth and depth of the topics in this symposium clearly displays that hip surgery remains a dynamic area of orthopaedic surgery and that the future of hip surgery will incorporate many new exciting concepts and technologies. Although many of these efforts will continue to be directed at joint replacement, there are many other areas of hip surgery that actively are being investigated and hold great promise for preservation of the hip joint.
Artificial emotional creature for human-machine interaction (2002)

This paper introduces the artificial emotional creature project that seeks to explore a different direction that is not so rigidly dependent on such objective measures as accuracy and speed. The goal of this project is to explore a new area in robotics, with an emphasis on human-machine interaction. There is a large body of evidence that shows the importance of the interaction between humans and animals such as pets. We have been building a pet robot, as an implementation of an artificial emotional creature, with the subjective appearance of "behaviors" that are dependent on internal states as well as external stimulation from both the physical environment and human beings. The pet robot has visual, auditory, and tactile sensors. This paper discusses the emergence of intelligence by non-verbal communication between human and robot through physical interaction.
Plasmid-linked Resistance to Inorganic Salts in Staphylococcus aureus (1968)

The penicillinase plasmids, a series of extrachromosomal resistance factors in Staphylococcus aureus, were found to carry determinants of resistance to a series of inorganic ions as well as resistance to penicillin and, in some cases, erythromycin. Most of the ions involved were inhibitory but not lethal to the bacteria; the resistance markers conferred an increase in resistance by comparison with susceptible organisms of between 3- and 100-fold, depending on the ion involved. Separate genetic loci for resistance to arsenate, arsenite, lead, cadmium, mercuric, and bismuth ions were demonstrated. Resistance to antimony and resistance to zinc were also found but were not separated genetically from resistance to arsenite and cadmium, respectively. The ion resistance markers appeared to form a cluster on the plasmid, with no other known marker within it. Naturally occurring plasmids were observed that lacked one or more of these ion resistance markers, as well as penicillinase-negative strains that were resistant to one or more of the ions. The patterns of markers carried by these various strains may provide some understanding of the evolution of a plasmid linkage group.
TPC and Non-TPC Based Topology Control Approaches for QoS Improvement in MR-WMN (2010)

A grand challenge in Multi-Radio Wireless Mesh Networks (MR-WMN) is to limit the interference such that its net capacity increases without compromising scalability and stability. In this chapter, the authors first provide an insight into the implications of transmit power control (TPC) on the MR-WMN topology and QoS. In this regard, a review of some of the key work is carried out they then explore the approach of non-TPC based topology control schemes for limiting the interference in a static nodes based MR-WMN system that uses a distributed, light-weight, cooperative multiagents. A path reduction (PR) algorithm is the principle behind our topology control scheme and its viability is explained through NetLogo tool based simulation results. The effectiveness of the PR algorithm is shown in terms of improved interference cost reduction and decrease in path length. The focus of this chapter is mainly on non-TPC approach rather than the TPC approach.
Quantitative Assessment of Parkinsonian Patients by Continuous Wrist Activity Monitoring (1993)

The aim of this study was to examine the quantitative relationship between activity monitor measures and clinical scores of patients with Parkinson disease (PD). Motor activity was recorded continuously for 5 to 6 days at home with a wrist-worn activity monitor in 69 PD patients and 59 healthy controls. Clinical scores of the patients, age, and sex were submitted to multiple regression analysis to examine the quantitative relationship with measures reflecting the activity level and the proportion of activity and immobility over time. The patients' age, sex, and scores representing hypokinesia and rigidity and resting tremor explained approximately 50% of the variance of the motor activity measures. All motor activity measures declined with age; the rate of decline was similar for the patients and controls. Sex emerged as a predictor of the motor activity measures in the patients only. Male patients with PD showed significantly lower values for all motor activity measures than female patients and controls. Our results show that activity monitoring can be used as an objective quantitative assessment in PD.
Pharmacokinetics of Thiamine Derivatives. I. Formation of Thiamine from Thiamine Propyl Disulfide by Erythrocytes of Rat (1970)

The processes of uptake of TPD (thiamine propyl disulfide) and formation of thiamine were investigated in detail, using the suspension of rat erythrocytes, since erythrocytes were most effective to form thiamine from TPD in blood. 1) The ratio of amount of thiamine formed in erythrocytes to that in the suspension medium was 1 : 1 after incubation of TPD in erythrocytes suspension. This ratio did not change remarkably, even when amount of erythrocytes was increased by 100 fold. 2) It was verified that TPD was converted to thiamine in the membrane under the influence of reducing compounds in erythrocytes and thiamine, which was formed there, went out and into erythrocytes with equal probability. 3) Process of formation of thiamine from TPD by erythrocytes was expressed by second order rate reaction kinetics, and its rate constant was determined.
Bombesin-Targeted PET of Prostate Cancer (2016)

Imaging plays an important role in prostate cancer (PC), including accurate evaluation of the extent of disease, assessment of sites of recurrent disease, and monitoring of response to treatment. Molecular imaging techniques are among the novel developments related to the imaging of PC, and various SPECT and PET radiopharmaceuticals are now available in clinical trials or commercially. Here we describe the preclinical and clinical use of gastrin-releasing peptide receptors as targets for the imaging of PC, with a focus on the development of PET tracers for the imaging of gastrin-releasing peptide receptor-positive tumors.
Di- and Zerovalent Platinaboratranes:  The First Pentacoordinate d10 Platinum(0) Complex (2004)

The reaction of [PtCl2(PPh3)2] with Na[HB(mt)3] (mt = methimazolyl) affords the platinaboratrane salt [PtH(PPh3){B(mt)3}]Cl(PtII→B), the first example of a metallaboratrane with the metal center in the +2 oxidation state. Base-induced dehydrochlorination affords the first d10 metallaboratrane, [Pt(PPh3){B(mt)3}](Pt0→B), based on an unprecedented pentacoordinate platinum(0) geometry.
X-Ray Crystallographic Analyses of Human α-Thrombin Complexed to Peptidyl Aminophosphonates: Evidence of a Binding Mechanism (1999)

We sought to study O,O-Diphenyl dipeptidylaminophosphonates and their interaction with the coagulation protease, human α-thrombin. The ‘fibrinogen-like’ recognition sequence D-Phe-Pro-Arg, is a template of high affinity for thrombin. This was modified by replacing the ‘PI’ Arg by a neutral side chain, and the unnatural amino acid diphenylalanine was used in place of the ‘P3’ Phe. The tripeptides of general formula D-Dpa-Pro-NHCHRP(OPh)2 are highly selective for thrombin amongst other serine proteases; and, more importantly for the design of an efficacious anti-thrombotic agent, show particularly low activity toward other coagulation serine proteases of the cascade. However the kinetics of thrombin inhibition were seen to be dependent on the compounds' structure. To explain this we have studied compounds (1), where R is pentyl and compound (2) where R is (3-methoxy)propyl, for which the kinetics of inhibition were analysed as competitive (2 μM) and slow, tight-binding (final Ki 20nM) respectively. Analysis of the X-Ray crystal structure of these compounds complexed to human α-thrombin, unusually shows no covalent bond formed between the phosphorus nucleus and the serine 195 in the catalytic site of the enzyme. These observations are at variance to the proposed mechanism of action of other phosphorus based serine protease inhibitors.
Scalable Implementation Of Unit Selection Based Text-To-Speech System For Embedded Solutions (2006)

In this paper we propose two methods in order to implement unit selection-based text-to-speech engine into resource-limited embedded systems. While we have achieved improving the quality of synthesized speech by unit selection-based text-to-speech technology, there is a practical problem regarding the trade-off between the size of database and the quality of synthesized speech. That is, we need large database and expensive computation in order to generate highly natural sounding voices, and the text-to-speech system is required to meet the specification of target system. For this problem, we introduced frequency-based approaches to reduce the size of speech database. The experimental results showed the step-by-step downsizing method was better than the direct one in terms of the cumulative join cost and the target cost. Furthermore, some techniques were introduced and evaluated in order to implement our text-to-speech engine into an embedded system. From experimental results, it developed that the run-time work load for the test sentences was 80 MIPS approximately and the implemented engine was useful and scalable for mid-class embedded system.
HUB Microfactory – PPA1 – Mefenamic acid – HME – 3D printing process stream (2019)

[no abstract]
Prognostics of lithium-ion batteries using a deterministic Bayesian approach (2015)

Lithium-ion batteries are popular for a wide variety of applications owing to their high energy/power density, long cycle life, and low self-discharge rate. A battery management system (BMS) can ensure the reliability and safety of batteries. As an important part of a BMS, prognostics and health management (PHM) can predict the failure time of batteries. This paper presents a new approach for battery prognostics based on a deterministic Bayesian approach. This approach can provide a probability density function (PDF) for the failure cycle. Based on the experiments, the battery capacity data collected under charge-discharge cycling conditions was used to validate the developed algorithm. The prediction results are updated over time as more data become available, which leads to an increase in prognostic accuracy. The prediction results provide a guideline for maintenance and replacement of batteries in electric vehicles (EVs).
Kampo Medicines for Mite Antigen‐Induced Allergic Dermatitis in NC/Nga Mice (2005)

We have established an allergic dermatitis model in NC/Nga mice by repeated local exposure of mite antigen for analyzing atopic dermatitis. We examined how four Kampo medicines, Juzen-taiho-to, Hochu-ekki-to, Shofu-san and Oren-gedoku-to, on the dermatitis model to obtain basic information on their usefulness for treating atopic dermatitis. Mite antigen (Dermatophagoides farinae crude extract) solution at a concentration of 10 mg/ml was painted on the ear of NC/Nga mice after tape stripping. The procedure was repeated five times, at 7 day intervals. An apparent biphasic ear swelling was caused after the fourth and fifth antigen exposures with elevated serum IgE levels and accumulation of inflammatory cells. In the cervical lymph nodes and ear lobes, the five procedures of antigen exposure induced interleukin-4 mRNA expression but reduced interferon-gamma mRNA expression. Oral administration of all four Kampo medicines inhibited the formation of ear swelling and inflammatory cell accumulation. Juzen-taiho-to and Hochu-ekki-to apparently prevented the elevation of serum IgE level. Furthermore, the four Kampo medicines showed a tendency to prevent not only the increase in interleukin-4 mRNA expression but also the decrease in interferon-gamma mRNA expression. The present results indicate that Juzen-taiho-to, Hochu-ekki-to, Shofu-san and Oren-gedoku-to may correct the Th1/Th2 balance skewed to Th2, and this activity helps inhibit dermatitis in NC/Nga mice. The ability of the Kampo medicines to correct the Th1/Th2 balance seems to underlie their effectiveness in treating of atopic dermatitis.
Prediction analysis of strata deformation by subway engineering based on artificial intelligence theory (2011)

Because the complication of subway engineering and uncertainty of influencing factors, traditional prediction methods of strata deformation by subway engineering are far from accuracy. In this paper, Visual C++6.0 is adopted to combine FLAC3D based on finite difference method with artificial neural network, to construct the artificial analysis method connecting normal analysis with back analysis. In normal analysis, soil parameters are generated by the random method considering the uncertainty of soil inherent properties, which also validates the prediction capacity of ANN on uncertainty. Comparing the predicting vertical and horizontal displacement by improved back analysis neural network (MBP) with the corresponding observed values, this paper concluded that the maximum and minimum error of vertical displacement is 9.75% and 0.18% respectively, and those of horizontal displacement is 8.92% and 0.08% respectively, which proved the scientificity and accuracy of the artificial intelligence theory applied on predicting strata deformation by construction of subway engineering.
The Burden of Cognitive Impairment in Patients With End-Stage Renal Disease and Impact on Dialysis Modality Choice (2016)

Patients' self-perception of cognitive ability is a significant predictor of self-care dialysis modality choice. Subjective report of "metaconcentration" is also strongly associated with poorer outcome on the TMT part B.
Determination of Actinide Isotope Ratios Using Glow Discharge Optogalvanic Spectroscopy (1997)

Diode-laser excited optogalvanic spectroscopy (OGS) of a glow discharge has been utilized to measure U-235/U-235 + U-238 isotope ratios. This ``optical mass spectrometric`` measurement has been demonstrated for a number of samples including uranium oxide, fluoride, and metal. Various diode-laser accessible atomic transitions in the 775 to 835 nm region have been evaluated; these transitions were chosen by considering OGS sensitivity and isotope shift. Using the 831.84 nm uranium line, for example, it was possible to measure the U-235/U-235 + U-238 isotope ratio (0.0026) of depleted uranium samples. A prototypical field instrument to make these measurements has been assembled and demonstrated. A U-236 spectral line was identified in a sample of enriched uranium, and an abundance sensitivity was measured.
Quality Control and Quality Assurance of Asphalt Mixtures Using Laboratory Rutting and Cracking Tests (2019)

The main objectives of this project were to review the available balanced-mix design (BMD) methodologies, understand the I-FIT and Hamburg Wheel Tracking Test (HWTT) test methods using INDOT asphalt mixtures, and to explore the application of these tests to both a BMD approach and as performance-related Quality Control (QC) and Quality Acceptance (QA) methods. Two QA mixture specimen types, plant-mixed laboratory-compacted (PMLC) and plant-mixed field-compacted (PMFC) were used in the determination of cracking and rutting parameters. Distribution functions for the flexibility index (FI) values and rutting parameters were determined for various mixture types. The effects of specimen geometry and air voids contents on the calculated Flexibility Index (FI) and rutting parameters were investigated. The fatigue characteristics of selected asphalt mixtures were determined using the S-VECD test according to different FI levels for different conditions. A typical full-depth pavement section was implemented in FlexPAVE to explore the cracking characteristics of INDOT asphalt mixtures by investigating the relationship between the FI values of QA samples with the FlexPAVE pavement performance predictions. The FI values obtained from PMFC specimens were consistently higher than their corresponding PMLC specimens. This study also found that FI values were affected significantly by variations in specimen thickness and air voids contents, having higher FI values with higher air voids contents and thinner specimens. These observations do not agree with the general material-performance expectations that better cracking resistance is achieved with lower air voids content and thicker layers. Additionally, PG 70-22 mixtures show the lowest mean FI values followed by the PG 76-22 and 64-22 mixtures. The same order was observed from the ΔTc (asphalt binder cracking index) of INDOT’s 2017 and 2018 projects. Finally, it was found that the HWTT showed reasonable sensitivity to the different characteristics (e.g., aggregate sizes, binder types, and air voids contents) of asphalt mixtures. Mixtures containing modified asphalt binders showed better rut resistance and higher Rutting Resistance Index (RRI) than those containing unmodified binders.
Dynamic Adaptation of the Peripheral Circulation to Cold Exposure (2011)

Humans residing or working in cold environments exhibit a stronger cold-induced vasodilation (CIVD) reaction in the peripheral microvasculature than those living in warm regions of the world, leading to a general assumption that thermal responses to local cold exposure can be systematically improved by natural acclimatization or specific acclimation. However, it remains unclear whether this improved tolerance is actually due to systematic acclimatization, or alternately due to the genetic pre-disposition or self-selection for such occupations. Longitudinal studies of repeated extremity exposure to cold demonstrate only ambiguous adaptive responses. In field studies, general cold acclimation may lead to increased sympathetic activity that results in reduced finger blood flow. Laboratory studies offer more control over confounding parameters, but in most studies, no consistent changes in peripheral blood flow occur even after repeated exposure for several weeks. Most studies are performed on a limited amount of subjects only, and the variability of the CIVD response demands more subjects to obtain significant results. This review systematically surveys the trainability of CIVD, concluding that repeated local cold exposure does not alter circulatory dynamics in the peripheries, and that humans remain at risk of cold injuries even after extended stays in cold environments.
A case of carotid body paraganglioma and haemangioblastoma of the spinal cord in a patient with the N131K missense mutation in the VHL gene (2011)

The article describes paraganglioma case in woman with von Hippel-Lindau disease. She was found to be a carrier of a rare germline mutation in the VHL gene (393C>A; N131K). The patient developed large, untypical for von Hippel-Lindau disease, carotid body paraganglioma at the common carotid artery bifurcation. The carotid body paraganglioma coexisted with the haemangioblastoma situated intramedullary in region C5/C6. The haemangioblastoma reached the right-sided dorsal part of the spinal cord in section C5/C6. It produced radicular symptoms within C5/C6, followed by the later paresis of the right limbs. The haemangioblastoma was resected completely. Twelve months after the operation, the spinal symptoms receded and the carotid body paraganglioma still was asymptomatic. The current case of carotid body paraganglioma in patient with the 393C>A (N131K) missense mutation in the VHL gene, supports association of this specific mutation and VHL disease type 2, and suggests its correlation with susceptibility to paragangliomas.