gebhart/patrepeval huggingface dataset:
A Carbene Analogue with Low-Valent Gallium as a Heteroatom in a quasi-Aromatic Imidazolate Anion (1999)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTA Carbene Analogue with Low-Valent Gallium as a Heteroatom in a quasi-Aromatic Imidazolate AnionEva S. Schmidt, Alexander Jockisch, and Hubert SchmidbaurView Author Information Anorganisch-chemisches Institut der Technischen Universität München Lichtenbergstrasse 4, D-85747 Garching, Germany Cite this: J. Am. Chem. Soc. 1999, 121, 41, 9758–9759Publication Date (Web):October 1, 1999Publication History Received26 July 1999Published online1 October 1999Published inissue 1 October 1999https://pubs.acs.org/doi/10.1021/ja9928780https://doi.org/10.1021/ja9928780rapid-communicationACS PublicationsCopyright © 1999 American Chemical SocietyRequest reuse permissionsArticle Views2305Altmetric-Citations195LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information SUBJECTS:Anions,Elements,Gallium,Heterocyclic compounds,Molecular structure Get e-Alerts
ChemInform Abstract: Synthesis of C‐Oligosaccharides That Mimic Their Natural O‐Analogous Immunodeterminants in Binding to Monoclonal Immunoglobulins. (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: DIE REAKTIVITAET BIOLOGISCH INTERESSIERENDER INDOLSYSTEME MIT 3‐PYRROLIN‐2‐ON (1971)

Abstract 3‐Pyrrolin‐2‐on (I) reagiert mit 2‐Propyl‐indol (II) unter Kondensation in 3‐Stellung zu (III), während mit Skatol (IVa) oder N‐Acetyl‐tryptamin (IVb) unter Angriff in 2‐Stellung die Derivate (Va) und (Vb) entstehen.
Cell surface antigens of Bordetella pertussis. (1985)

Cell surface-specific radiolabelling techniques, monoclonal antibody analyses, and chemical and physical isolation of cell fractions were used to study the surface of B. pertussis cells. Four surface specific proteins were identified by radioiodination and monoclonal antibody techniques. These included the filamentous hemagglutinin (FHA), and three outer membrane proteins-OMP91, OMP18 and OMP15. Membrane blebs were isolated from culture supernatants and shown to contain LPSII, pertussis toxin (PT), FHA, OMP91, and OMP18, but not OMP15. The level of LPS I in blebs appeared to be reduced from the level in cell envelopes. Bleb fractions contained enzymatically active adenylate cyclase (AC), and biologically active dermonecrotic toxin (DNT) and PT. Blebs were also toxic for mice, even when heated to 80 degrees C for 30 minutes. To explain these data, we propose that membrane blebs comprise an effective toxin delivery system, and that the cell surface of B. pertussis is composed of at least two domains.
High-k gate stack on germanium substrate with fluorine incorporation (2008)

In this letter, a postgate CF4-plasma treatment is proposed and demonstrated on germanium (Ge) metal-oxide-semiconductor capacitors and the effects of fluorine (F) incorporation have been studied on both high-k∕Ge gate stacks without any surface passivation and with Si surface passivation. Our results show that F is effectively introduced into the gate stack by CF4 treatment and segregates near high-k∕Ge interface. Electrical characteristics such as frequency dispersion, interface state density (Dit), and gate leakage are improved after F incorporation. Interface quality of high-k∕Ge gate stack is further improved by combining Si surface passivation and postgate CF4 treatment, with its Dit as low as 4.85×1011cm−2eV−1.
Intrastrand cross-links are not formed in the reaction between transplatin and native DNA: relationm with the clinical inefficency of transplatin (1995)

The reaction between trans-diamminedichloroplatinum(II) and single-stranded oligonucleotides containing the sequence d(GXG) (X being an adenine, cytosine or thymine residue) yields trans-[Pt(NH3)2[(GXG)-GN7,GN7]] intrastrand cross-links. These cross-links do not prevent the pairing of the platinated oligonucleotides with their complementary strands but they decrease the thermal stability of the duplexes. The thermal stability is not much affected by the chemical nature of the X residue and its complementary base. By gel electrophoresis, it is shown that the trans- [Pt(NH3)2[d(GTG)-GN7,GN7]] cross-link bends the DNA double helix (26 degrees) and unwinds it (45 degrees). The pairing of the platinated oligonucleotides with their complementary strands promotes the rearrangement of the 1,3-intrastrand cross-links into interstrand cross-links. At a given temperature, the nature of the X residue, its complementary base and of the base pairs adjacent to the adducts do not dramatically affect the rate of the reaction. To know whether trans-[Pt(NH3)2[d(GXG)-GN7,GN7]] cross-links do not rearrange in some sequences, the location of these adducts was searched in double-stranded DNA after reaction with trans-diamminedichloroplatinum(II) by means of the 3'-5' exonuclease activity of T4 DNA polymerase. At low level of platination, trans-[Pt(NH3)2[d(GXG)-GN7,GN7]] cross-links were not detected. Monofunctional adducts and interstrand cross-links were mainly formed. These results are discussed in relation with the clinical inefficiency of trans-diamminedichloroplatinum(II).
Preliminary feasibility analysis of remote subject identification during hemodynamic monitoring by Radio Frequency Impedance (2011)

Non-contact, non-invasive monitoring of hemodynamic parameters would be ideal for medical monitoring in a variety of environments. Radio Frequency Impedance Interrogation (RFII) measures hemodynamic function via resonance frequency coupling to a hydrophilic protein molecule. While the application of this technology to hemodynamic monitoring has demonstrated initial success, this preliminary study examined the use of RFII for subject identification by waveform signal analysis, which would allow confirmation of the identity of a subject in an operational setting prior to rescue efforts. Preliminary results demonstrate an excellent recognition rate using the RFII signature and pattern classification. Each individual has a consistent pattern during the initial waveform identification period that is visually distinct from the other individuals in the data set. These results suggest that RFII may be of great utility in the pre-hospital triage setting for patient monitoring and for the rapid identification of subjects in the operational setting.
Interactions of Potential Anti-COVID-19 Compounds with Multispecific ABC and OATP Drug Transporters (2021)

During the COVID-19 pandemic, several repurposed drugs have been proposed to alleviate the major health effects of the disease. These drugs are often applied with analgesics or non-steroid anti-inflammatory compounds, and co-morbid patients may also be treated with anticancer, cholesterol-lowering, or antidiabetic agents. Since drug ADME-tox properties may be significantly affected by multispecific transporters, in this study, we examined the interactions of the repurposed drugs with the key human multidrug transporters present in the major tissue barriers and strongly affecting the pharmacokinetics. Our in vitro studies, using a variety of model systems, explored the interactions of the antimalarial agents chloroquine and hydroxychloroquine; the antihelmintic ivermectin; and the proposed antiviral compounds ritonavir, lopinavir, favipiravir, and remdesivir with the ABCB1/Pgp, ABCG2/BCRP, and ABCC1/MRP1 exporters, as well as the organic anion-transporting polypeptide (OATP)2B1 and OATP1A2 uptake transporters. The results presented here show numerous pharmacologically relevant transporter interactions and may provide a warning on the potential toxicities of these repurposed drugs, especially in drug combinations at the clinic.
Large full band gaps for photonic crystals in two dimensions computed by an inverse method with multigrid acceleration (2003)

In this study, two fast and accurate methods of inverse iteration with multigrid acceleration are developed to compute band structures of photonic crystals of general shape. In particular, we report two-dimensional photonic crystals of silicon air with an optimal full band gap of gap-midgap ratio Deltaomega/omega(mid)=0.2421, which is 30% larger than ever reported in the literature. The crystals consist of a hexagonal array of circular columns, each connected to its nearest neighbors by slender rectangular rods. A systematic study with respect to the geometric parameters of the photonic crystals was made possible with the present method in drawing a three-dimensional band-gap diagram with reasonable computing time.
A novel high‐viscosity, two‐solution acrylic bone cement: Effect of chemical composition on properties (1999)

Solutions of poly(methyl methacrylate) (PMMA) powder predissolved in methyl methacrylate (MMA) have been developed as an alternative to current powder/liquid bone cements. They utilize the same addition polymerization chemistry as commercial cements, but in mixing and delivering via a closed system, porosity is eliminated and the dependence of material properties on the surgical technique is decreased. Twelve different sets of compositions were prepared, with two solutions of constant polymer-to-monomer ratio (80 g of PMMA/100 mL of MMA) and all combinations of four benzoyl peroxide (BPO) initiator levels added to the first solution and three N,N-dimethyl-p-toluidine (DMPT) activator levels added to the second. These compositions were tested, along with Simplex-P bone cement, for effects of BPO and DMPT concentrations on polymerization exotherm, setting time, flexural strength, modulus, and maximum strain. The results show that each of these dependent variables was affected significantly by the individual concentrations of BPO and DMPT and their interactions. The flexural strength, modulus, and polymerization exotherm reached their maximums at about a 1:1 molar ratio of BPO to DMPT. Most compositions had exotherms, setting times, and maximum strains within the range of commercial cements and flexural strengths and moduli up to 54 and 43% higher than Simplex-P, respectively. © 1999 John Wiley & Sons, Inc. J Biomed Mater Res, 47, 36–45, 1999.
A node discovery service for partially mobile sensor networks (2007)

Wireless Sensor Networks (WSNs) are challenging types of networks where resources can be scarce. In particular, battery is often a very limited resource and the radio interface is the culprit for most of the energy consumption. This makes any discovery of other sensors a difficult task, less cumbersome if sensors are fixed but crucial if (some) sensors start being mobile (such as in wildlife monitoring projects with tagged animals). In this paper we propose a middleware offering node discovery for partially mobile wireless sensor networks, where fixed nodes (sinks), deployed in the environment to monitor the movement of entities, detect those patterns with low power consumption. The approach is based on various machine learning techniques which allows for learning and adapting the wake up strategy of the sinks dynamically. We also report on the evaluation of the approach through simulation and use of real movement traces.
Complex Bloch-modes calculation of plasmonic crystal slabs by means of finite elements method (2012)

We present a Finite Element Method (FEM) to calculate the complex valued k(omega) dispersion curves of a photonic crystal slab in presence of both dispersive and lossy materials. In particular the method can be exploited to study plasmonic crystal slabs. We adopt Perfectly Matched Layers (PMLs) in order to truncate the open boundaries of the model, including their related anisotropic permittivity and permeability tensors in the weak form of Helmholtz's eigenvalue equation. Results of the model are presented in the interesting case of a holey metal film enabling to study the observed extraordinary optical transmission properties in term of the plasmonic Bloch modes of the structure.
Breaking the Circuit-Size Barrier in Secret Sharing. (2018)

We study secret sharing schemes for general (non-threshold) access structures. A general secret sharing scheme for n parties is associated to a monotone function F: {0, 1}n → {0, 1}. In such a scheme, a dealer distributes shares of a secret s among n parties. Any subset of parties T ⊆ [n] should be able to put together their shares and reconstruct the secret s if F(T) = 1, and should have no information about s if F(T) = 0. One of the major long-standing questions in information-theoretic cryptography is to minimize the (total) size of the shares in a secret-sharing scheme for arbitrary monotone functions F. Keywords: Information-theoretic techniques; Security and privacy; Cryptography; Theory of computation; Computational complexity and cryptography; Circuit complexity; Communication complexity; Cryptographic protocols
Références (2001)

Acosta-Solis M., 1968 — Division fitogeográfica y formaciones geo-botánicas del Ecuador. Quito, Casa de la Cultura ecuatoriana, 307 p.Acosta-Solis M., 1976 — Investigadores de la geografía y de la naturaleza de America tropical. Quito, 1PGH, Biblioteca Ecuador, 201 p.Albrecht A.,
Abstract P32 (2013)

AMERICAN SOCIETY OF PLASTIC SURGEONS PLASTIC & RECONSTRUCTIVE SURGERY PRS GLOBAL OPEN ASPS EDUCATION NETWORK AMERICAN SOCIETY OF PLASTIC SURGEONS PLASTIC & RECONSTRUCTIVE SURGERY PRS GLOBAL OPEN ASPS EDUCATION NETWORK
The disintegration of boron by slow neutrons. II (1948)

A further study has been made of the disintegration of boron by slow neutrons, B 10 ( n , α) Li, in the cloud chamber. The total ranges of the α -particles and the lithium particles were measured and two groups found. 91·4 % of the disintegrations form the main group, which was previously measured, and 8·6 % a long-range group corresponding to the lithium being left in the ground state. The results of the previous measurements are corrected for the variation of stopping power with velocity and the ranges in standard air of the particles of the two groups are now given as 7·7 mm. α-particle and 4·8 mm. lithium particle, total 12·5 mm. for the main group, and 9·3 mm. α-particle and 5·6 mm. lithium particle, total 14·9 mm. for the long-range group. These results, taken together with those of other workers, make it certain that in about 92 % of disintegrations the lithium is left in an excited state of about 0·47 MeV. energy and in the remaining 8 % in the ground state. The energies calculated from this scheme by using the known masses do not agree with those deduced from the measured ranges and the range-energy relation for a-particles. It is suggested that the rangeenergy relation is at fault and that these measurements provide two experimental points to which a range-energy relation should be fitted.
Front Cover: The Intermetalloid Clusters [Ni2Bi12]4+ and [Rh2Bi12]4+ – Ionothermal Synthesis, Crystal Structures, and Chemical Bonding (Z. Anorg. Allg. Chem. 3/2019) (2019)

The cover picture shows the cationic cluster [Rh2Bi12]4+. This new polycation crystallizes as tetrabromido-aluminate salt after dissolution of the complex precursor Bi12–xRhBr13–x (0 < x < 1) in the Lewis-acidic ionic liquid [BMIm]Br·4.1AlBr3 (BMIm = 1-butyl-3-methylimidazolium). The cluster salt Bi12–xRhBr13–x, which was used as starting material, consists of homonuclear polycations Bi5+ and Bi62+ as well as cubocahedral clusters [RhBi6X12]–. These units, together with the constituent ions of the ionic liquid, are visualized in the background of the picture to symbolize the surrounding solution. [Rh2Bi12]4+ has 50 valence electrons (VE) and thus two VE less than its nickel congener, [Ni2Bi12]4+, which was obtained by reacting elemental bismuth and nickel chloride in a similar chloride-based ionic liquid. [Ni2Bi12]4+ does not show the folded bicyclic “butterflies” or the splitting of the central bismuth square into two dumbbells, but three regular bismuth squares in an D4h-symmetric triple-decker cluster. This structural motif is also known from cationic complexes, such as [Mo2Te12]6+ (54 VE), and anionic intermetalloid clusters, such as [Ni2Bi5Pb7]3− (52 VE). Chemical bonding analyses classify [Ni2Bi12]4+ and [Rh2Bi12]4+ on the crossroads between complexes with strong, oriented metal-ligand bonding and intermetallic nanoparticles with extended multicenter bonding. More details are discussed in the article by Ruck et al. on page 161 ff.
Amerindian mitochondrial DNAs have rare Asian mutations at high frequencies, suggesting they derived from four primary maternal lineages. (1990)

The mitochondrial DNA (mtDNA) sequence variation of the South American Ticuna, the Central American Maya, and the North American Pima was analyzed by restriction-endonuclease digestion and oligonucleotide hybridization. The analysis revealed that Amerindian populations have high frequencies of mtDNAs containing the rare Asian RFLP HincII morph 6, a rare HaeIII site gain, and a unique AluI site gain. In addition, the Asian-specific deletion between the cytochrome c oxidase subunit II (COII) and tRNA(Lys) genes was also prevalent in both the Pima and the Maya. These data suggest that Amerindian mtDNAs derived from at least four primary maternal lineages, that new tribal-specific variants accumulated as these mtDNAs became distributed throughout the Americas, and that some genetic variation may have been lost when the progenitors of the Ticuna separated from the North and Central American populations.
The Functional Heterogeneity of Type 1 Effector T Cells in Response to Infection Is Related to the Potential for IFN-γ Production (2005)

The expression of IFN-gamma is a hallmark of Th1 cells and CD8(+) effector T cells and is the signature cytokine of type 1 responses. However, it is not known whether T cells are homogeneous in their capacity to produce IFN-gamma, whether this potential varies between tissues, and how it relates to the production of other effector molecules. In the present study we used bicistronic IFN-gamma-enhanced yellow fluorescent protein (IFN-gamma-eYFP) reporter mice (Yeti) and MHC class I tetramers to directly quantify IFN-gamma expression at the single cell level. The eYFP fluorescence of Th1 cells and CD8(+) effector T cells was broadly heterogeneous even before cell division and correlated with both the abundance of IFN-gamma transcripts and the secretion of IFN-gamma upon stimulation. CD4(+) and CD8(+) T cells of influenza-infected mice revealed a similarly heterogeneous IFN-gamma expression, and eYFP(high) cells were only found in the infected lung. Ag-specific T cells were in all examined tissues eYFP(+), but also heterogeneous in their reporter fluorescence, and eYFP(high) cells were also restricted to the infected lung. A similar heterogeneity was observed in Toxoplasma gondii-infected animals, but eYFP(high) cells were restricted to different tissues. Highly eYFP fluorescent cells produced elevated levels of proinflammatory cytokines and chemokines in addition to IFN-gamma, suggesting their coregulated expression as a functional unit in highly differentiated effector T cells.
Transition‐Metal‐Free Synthesis of Nitrogen Containing Heterocycles With Fully Substituted N‐fused Pyrrole Rings (2015)

Abstract The efficient synthesis of C‐2 alkylated indolizine, pyrrolo[1,2‐ a ]isoquinoline, and pyrrolo[1,2‐ a ]quinoline derivatives utilizing a single reactivity platform is described. Employing a [3+2] dipolar cycloaddition reaction between heterocyclic N ‐ylides and allenoates, the incorporation of C‐2 alkyl substituents was achieved resulting in various N ‐fused heterocycles with a fully substituted pyrrole ring. This metal‐free route employing allenoates as a dipolarophile solves the longstanding limitations of functional diversity at the C‐2 position and the efficient creation of the pyrrolo[1,2‐ a ]quinoline motif.
Pareto Optimal Distributed Beamforming for the Multi-Band Multi-Cell Downlink (2017)

In this paper, we consider a multi-cell multi-band downlink where the base-station (BS) in each cell has multiple transmit antennas and each cell has one active mobile station (MS) with a single receive antenna and treats interference from the other cells as noise. There is a sum transmit power constraint for each BS over all the bands. An alternating maximization (AM) algorithm is proposed to determine the optimal power allocation among the bands and the optimal beamforming vectors for each BS in each band. This algorithm can be implemented in a distributed manner with limited exchange of interference constraints between the BSs. Using simulations, the algorithm is shown to converge to the weighted sum rate optimal point on the Pareto boundary of the achievable rate region. Furthermore, significant performance gain is observed compared to: (i) equal power allocation across bands and weighted sum rate optimization in each band, (ii) zero-forcing (ZF) beamforming, and (iii) maximal ratio transmission (MRT) beamforming.
Is the diagnosis of atypical glandular cells of undetermined significance associated with greater risk at an inner city hospital? (2011)

Patients with AGC Pap results at our inner city hospital have a high risk for underlying significant pathology.
Serve sequence optimization of multiple bus signal priority requests based on dynamic programming (2009)

The serve sequence of multiple bus signal priority requests was optimized using a dynamic programming method to improve bus system management in large volume,high frequency systems.The problem was formulated as a multi-stage decision making problem.A case study used the signal-phase minimum green-light time as a constraint while minimizing the total pedestrian and vehicular delays as objectives.The results show that the method reduces both the total pedestrian delay and the total vehicular delay of priority requests compared with the traditional first-come-first-serve serve sequence and is efficient even for very strictly constraints.