gebhart/patrepeval huggingface dataset:
Alzheimer disease biomarkers, attentional control, and semantic memory retrieval: Synergistic and mediational effects of biomarkers on a sensitive cognitive measure in non-demented older adults. (2014)

The combined influence of attentional control with semantic retrieval is a marker of symptomatic AD and a sensitive correlate of established biomarkers for AD risk in cognitively healthy participants. The biomarkers influenced cognition primarily through increased levels of amyloid in the brain.
Dispersion Compensation for PLCI Based on Fringe Peak Estimation and Polynomial Fitting (2020)

Polarized low-coherence interferometry (PLCI) is a promising technology to absolute displacement measurement and sensor demodulation. To avoid jump errors induced by dispersion and achieve a high response, a dispersion compensation method based on fringe peak position estimation and polynomial fitting is proposed to get rid of the dependence on the priori model and birefringence parameters, and make this method very robust. The nearly linear resolution between the envelope and m -order PLCI fringe (PLCIF) centers are found and verified with both Gauss and non-Gauss profile broadband light sources. Then, the zero-order PLCIF is estimated and located to demodulate the measurement displacement. The demodulated results are significantly influenced by dispersion of the birefringence optical wedge and then polynomial fittings of sensing curve are conducted to raise the sensing accuracy. In comparison to the priori model and parameters based method, the proposed method can effectively avoid jump errors and has a higher accuracy than the directly envelope center method. Experimental results indicate that the measurement accuracy is higher than 19.5 nm which is enhanced by 6.88 times, the resolution is better than 2 nm, and its processing data rate can reach 35 kHz on an embedded system.
A practical approach for the design of multivariable control systems (2003)

In this paper the design of linear multivariable control systems based on the l_{1} - system norm is revised. It is shown how the well known computational difficulties inherent in this design problem can be overcome. For this purpose a procedure is proposed consisting of the steps 1) design of a suitable low order controller by semidefinite programming, 2) parametrization of all stabilizing conrollers based on the controller of the first step, 3) solution of the design problem with linear programming methods. The efficiency of this method is demonstrated by an example.
Mushroom tumor: a new disease onFlammulina velutipescaused byOchrobactrum pseudogrignonense (2015)

Mushroom tumor on Flammulina velutipes has become the main disease during the off-season cultivation of F. velutipes while the causal organism has remained unknown. The present study was aimed at identifying the pathogen confirming its pathogenisity following Koch's Postulates, characterizing it using morphological, physiological, biochemical and molecular features, and studying its current distribution. We determined that mushroom tumor is a new bacterial infection disease caused by Ochrobactrum pseudogrignonense. It produces tumor-like structures on the surface of the substrate, and inhibits the formation of primordia and fruiting of F. velutipes. The molecular studies showed that this new pathogen is closely related to Ochrobactrum based on 16S rRNA sequences. This is the first time that Ochrobactrum has been shown to be a pathogen of a mushroom.
ChemInform Abstract: Iodine(III)‐Mediated para‐Selective Direct Imidation of Anilides. (2015)

Abstract The imidation of acetanilides proceeds exclusively para‐selectively under iodine(III)‐mediated stoichiometric or catalyzed reaction conditions with good tolerance to various functional groups at both ortho or meta position.
Regional Patterns of Nasal Decongestion (2012)

Objective We present a study investigating the effect of a decongestant on the nasal mucosa, showing results in terms of the change in erectile tissue volume (ETV) in normal subjects using high resolution 3T‐MRI scanning. Method Seven volunteers with no nasal complaints (SNOT‐22) or obvious rhinoscopic abnormalities were studied. Each subject underwent 2 MRI scans producing a series of 120 contiguous 1.2 mm sections pre‐ and postdecongestion. Patients were decongested with xylometazoline‐HCL, remaining immobilized following the first scan. The scans were segmented using ITK‐Snap and analyzed using MATLAB. Results Subject age ranged from 21‐38 years (mean = 28). The SNOT‐22 scores ranged from 1‐10 (mean = 4.8). Decongestion had the greatest effect in 3 sites: the inferior turbinates, middle turbinates, and septum. The greatest change in ETV was observed in the inferior turbinates ( P &lt;.005), reducing by up to 1/3 at the posterior aspect of the inferior turbinate following decongestion. Changes were also seen in ETV of the middle turbinate and septal mucosa to a lesser extent. Conclusion The effect of decongestion on ETV has been investigated here in far greater detail than previously studied, and at higher spatial resolution. 3T‐MRI was found to be an excellent modality for mapping changes in nasal mucosa. Our results demonstrate the significant effect of decongestion on ETV of the inferior turbinates.
Association of brain heptachlor epoxide and other organochlorine compounds with lewy pathology (2018)

Organochlorine pesticides are associated with the presence of Lewy pathology in the brain, even after exclusion of PD cases. Although most of the association is through heptachlor epoxide, the role of other organochlorine compounds is in need of clarification. © 2018 International Parkinson and Movement Disorder Society.
Chronoamperometric Sizing and Locating of Spherical Particles via Potential-Step Transients (2007)

The precise size of a spherical glass particle, its distance from the center of a microdisk electrode, and its exact location within an array of three noncollinear microdisk electrodes are determined by using simple Cottrellian-like potential-step chronoamperometric experiments. To first elucidate the size of a glass sphere and its distance from the center of the electrode, the sphere was positioned at arbitrary distances between the center of the sphere and the center of the electrode and a potential-step transient was recorded. The size of the sphere and the center-to-center distance is then deduced by comparison of the experimental current−time response with lattice Boltzmann simulations. The radius of the sphere and its distance from the center of the electrode is then confirmed, independently, by a microscopic measurement of the radius of the sphere and the center-to-center distance at the time of the electrochemical measurement. Second, the location of the sphere is elucidated in a so-called “triangulation” experiment in which the sphere was positioned in an array of three microdisk electrodes; the current−time response for each electrode was recorded individually and then compared with simulations. Excellent agreement between experiment and independent direct observation was found.
Quantum simulations of one dimensional quantum systems (2016)

We present quantum algorithms for the simulation of quantum systems in one spatial dimension, which result in quantum speedups that range from superpolynomial to polynomial. We first describe a method to simulate the evolution of the quantum harmonic oscillator (QHO) based on a refined analysis of the Trotter-Suzuki formula that exploits the Lie algebra structure. For total evolution time t and precision e > 0, the complexity of our method is O(exp(γ√log(N/e))), where γ > 0 is a constant and N is the quantum number associated with an energy cutoff of the initial state. Remarkably, this complexity is subpolynomial in N/e. We also provide a method to prepare discrete versions of the eigenstates of the QHO of complexity polynomial in log(N)/e, where N is the dimension or number of points in the discretization. Next, we consider a system with a quartic potential. Our numerical simulations suggest a method for simulating the evolution of sublinear complexity O(N1/3+o(1)), for constant t and e. We also analyze complex one-dimensional systems and prove a complexity bound O(N), under fairly general assumptions. Our quantum algorithms may find applications in other problems. As an example, we discuss a generalization of the Fourier transform that is useful for signal analysis and can be formulated in terms of the evolution of the QHO.
ChemInform Abstract: α‐Aminoester‐Derived Imidazoles by 1,5‐Electrocyclization of Azavinyl Azomethine Ylides. (2009)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Immune modulator and antiviral potential of dendritic cells pulsed with both hepatitis B surface antigen and core antigen for treating chronic HBV infection (2010)

The immune modulatory capacities of HBsAg/HBcAg-pulsed DC in HBV TM in vivo, and in patients with CHB in vitro, inspire optimism about a clinical trial with this cell-based vaccine in patients with CHB.
Comparison in processability and mechanical and thermal properties of ethylene–octene copolymer crosslinked by different techniques (2004)

Abstract The crosslinking of metallocene ethylene–octene copolymer was investigated. The crosslinked polymers were prepared using two different techniques, i.e., peroxide crosslinking and silane–water crosslinking. In the former, the crosslinking reaction was conducted in a twin‐screw extruder, in the presence of dicumylperoxide. In the latter, the polymer was first grafted with vinyl trimethoxysilane in the extruder and subsequently crosslinked with water. The paper aims at investigation of the differences between these two techniques, in terms of processing and product mechanical and thermal properties. The results showed that the silane‐crosslinked polymers could be prepared with much higher gel contents than the peroxide‐crosslinked samples. The silane‐crosslinked polymers also retained the elastomeric characteristics of the pure polymer and showed remarkably higher extensibility, better thermal stability, and energy storage capacity. An explanation for the property differences between peroxide‐crosslinked and silane‐crosslinked polymers was proposed. © 2004 Wiley Periodicals, Inc. J Appl Polym Sci 93: 1179–1185, 2004
[Laparoscopic treatment of an isolated ureteropelvic junction disruption following blunt abdominal trauma]. (2006)

Isolated disruption of the ureteropelvic junction following blunt abdominal trauma is rare, although not exceptional. The diagnosis may be delayed. CT-scan with excretory phase imaging is the usual mode of diagnosis. The urinary tract can be repaired by an ureteropyelic anastomosis over a stent. The authors report the first case of an isolated disruption of the ureteropelvic junction following blunt abdominal trauma repaired by retroperitoneal laparoscopy.
In-plane photonic crystal microcavities for high-Q optical resonators (1999)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text A. Scherer, "In-plane photonic crystal microcavities for high-Q optical resonators," in Integrated Photonics Research, OSA Technical Digest Series (Optica Publishing Group, 1999), paper RTuH1. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Susceptibility of a Malathion-Resistant Strain of Indianmeal Moths (Lepidoptera: Pyralidae) to Bacillus thuringiensis Berliner (1984)

A malathion-resistant strain of Plodia interpunctella (Hübner) (IMM), was tested for susceptibility to Bacillus thuringiensis Berliner (Bt). Five different instars were exposed to six concentrations of Dipel and Thuricide by mixing. each formulation in a turkeymash- based culture medium which served as the food. Early instars were more susceptible than the later instars to Bt (P < 0.01) while all were more susceptible to Dipel than to Thuricide (P < 0.001). The period of growth and development of the larval-vasextended by exposure to the Bt from each formulation. Differences in larval susceptibility to Bt may result from the immunity and behavior of the larvae or the relative potency and repellency of Dipel versus Thuricide.
Impact of IL-17RA on neutrophil recruitment to the lung following infection with mycobacteria (2012)

Communication orale
Diagnosis and therapy surveillance in Addison's disease: rapid adrenocorticotropin (ACTH) test and measurement of plasma ACTH, renin activity, and aldosterone. (1992)

The rapid ACTH injection test is an indirect screening test for adrenocortical insufficiency. As a supplement to this test, we evaluated the practicability of single measurements of plasma cortisol, ACTH, aldosterone, and PRA as a definitive diagnostic test of primary adrenocortical insufficiency (PAI). We also tested the value of PRA measurements during treatment with hydro- and fludrocortisone (HC and FC) as a guide for correct mineralocorticoid substitution. In 45 patients with PAI, results of the rapid ACTH test and single measurements of the four hormones (all tests between 0800-0900 h) were compared. Single hormone measurements were also made in 55 normal subjects and 46 patients with pituitary disease (cortisol and ACTH only), most of them with mild to severe secondary adrenocortical insufficiency (SAI). The rapid ACTH test was abnormal in 100% of 41 patients with PAI tested. Plasma ACTH, PRA, and the ratios of ACTH/cortisol and PRA/plasma or urinary aldosterone were clearly elevated in 100% of the patients with PAI. The ACTH/cortisol ratio also distinguished 100% of patients with PAI from those with SAI, but not always control subjects from those with SAI. Thus, dynamic tests (CRH or insulin tests) are indicated if SAI is suspected. PAI and involvement of zona fasciculata and glomerulosa function can be diagnosed with high reliability by measuring cortisol, ACTH, aldosterone, and PRA either together with the rapid ACTH test or later, after a short interval of steroid substitution. PRA measurements during treatment with HC and FC correlated better with the mineralocorticoid dose than plasma potassium and sodium levels. PRA measurement is a valuable guide for FC replacement therapy. It should be titrated into the upper normal range to avoid under- and overtreatment.
Dynamic Stabilization of Metastable States in Triple‐Well Ferroelectric Sn2P2S6 (2023)

Polarization dynamics in ferroelectric materials is governed by the effective potential energy landscape of the order parameter. The unique aspect of ferroelectrics compared to many other transitions is the possibility of more than two potential wells, leading to complicated energy landscapes with new fundamental and functional properties. Here, direct dynamic evidence is revealed of a triple-well potential in the metal thiophosphate Sn<sub>2</sub> P<sub>2</sub> S<sub>6</sub> compound using multivariate scanning probe microscopy combined with theoretical simulations. The key finding is that the metastable zero polarization state can be accessed through a gradual switching process and is stabilized over a broad range of electric fields. Simulations confirm that the observed zero polarization state originates from a kinetic stabilization of the nonpolar state of the triple-well, as opposed to domain walls. Dynamically, the triple-well of Sn<sub>2</sub> P<sub>2</sub> S<sub>6</sub> becomes equivalent to antiferroelectric hysteresis loops. Therefore, this material combines the robust and well-defined domain structure of a proper ferroelectric with dynamic hysteresis loops present in antiferroelectrics. Moreover, the triple-well enhances mem-capacitive effects in Sn<sub>2</sub> P<sub>2</sub> S<sub>6</sub> , which are forbidden for ideal double-well ferroelectrics. These findings provide a path to tunable electronic elements for beyond binary high-density computing devices and neuromorphic circuits based on dynamic properties of the triple-well.
EARLY FLOWERING3 Encodes a Novel Protein That Regulates Circadian Clock Function and Flowering in Arabidopsis (2001)

Karen A. Hicks, Tina M. Albertson, D. Ry Wagner, EARLY FLOWERING3 Encodes a Novel Protein That Regulates Circadian Clock Function and Flowering in Arabidopsis, The Plant Cell, Vol. 13, No. 6 (Jun., 2001), pp. 1281-1292
AHK5 Histidine Kinase Regulates Root Elongation Through an ETR1-Dependent Abscisic Acid and Ethylene Signaling Pathway in Arabidopsis thaliana (2006)

The Arabidopsis thaliana genome encodes a small family of histidine (His) protein kinases, some of which have redundant functions as ethylene receptors, whereas others serve as cytokinin receptors. The most poorly characterized of these is authentic histidine kinase 5 (AHK5; also known as cytokinin-independent 2, CKI2). Here we characterize three independent ahk5 mutants, and show that they have a common phenotype. Our results suggest that AHK5 His-kinase acts as a negative regulator in the signaling pathway in which ethylene and ABA inhibit the root elongation through ETR1 (an ethylene receptor).
Combined Use of Growth Factors to Stimulate the Proliferation of Hematopoietic Progenitor Cells after Autologous Bone Marrow Transplantation for Lymphoma Patients (1996)

We studied the kinetic response and concentration of bone marrow (BM) progenitor cells of patients with lymphoid malignancies submitted to autologous bone marrow transplantation (ABMT), treated with a granulocyte-colony-stimulating factor (G-CSF)/interleukin-3 (IL-3) combination. The results were compared with those of lymphoma patients receiving the same pretransplant conditioning regimen followed by G-CSF alone. Recombinant human (rh)G-CSF was administered as a single subcutaneous (s.c.) injection at the dose of 5 micrograms/kg/day from day + 1 after reinfusion of autologous stem cells, while rhIL-3 was added from day +6 at the dose of 10 micrograms/kg/day s.c. (overlapping schedule). In both groups (i.e. G-CSF- and G-CSF/IL-3-treated patients), cytokine administration was discontinued when the absolute neutrophil count was > 0.5 x 10(9)/l of peripheral blood for 3 consecutive days. Following treatment with the CSF combination, the percentage of marrow CFU-GM and erythroid progenitors (BFU-E) in the S phase of the cell cycle increased from 9.3 +/- 2 to 33.3 +/- 12% and from 14.6 +/- 3 to 35 +/- 6%, respectively (p < 0.05). The number of actively cycling megakaryocyte progenitors (CFU-MK and BFU-MK) also increased. Conversely, G-CSF augmented the proliferative rate of CFU-GM (22.6 +/- 6% compared to a baseline value of 11.5 +/- 3%; p < 0.05) but not of BFU-E, CFU-MK or BFU-MK, and the increase in S-phase CFU-GM was significantly lower than that observed in the posttreatment samples of patients receiving IL-3 in addition to G-CSF. The absolute number of both CFU-GM and BFU-E/ml of BM was significantly augmented after treatment with G-CSF/IL-3 but not G-CSF alone. Similarly, administration of the cytokine combination resulted in a higher number of CD34+ cells and their concentration was significantly greater than that observed in the posttreatment samples of G-CSF patients. We also investigated the responsiveness to CSFs, in vitro, of highly enriched CD34+ cells, collected after priming with G-CSF in vivo (i.e. after 5 days of G-CSF administration). Our results demonstrated that pretreatment with G-CSF modified the response of BM cells to subsequent stimulation with additional CSFs. When the hematological reconstitution of patients treated with G-CSF/ IL-3 was compared to that of individuals receiving G-CSF alone, the addition of IL-3 resulted in a significant improvement in granulocyte and platelet recovery, a lower transfusion requirement and shorted hospitalization. In conclusion, our results indicate that in vivo administration of two cytokines increases the proliferative our results indicate that in vivo administration of two cytokines increase the proliferative our results rate and concentration of BM progenitor cells better than G-CSF alone and support a role for growth factor combinations for accelerating hematopoietic recovery after high-dose chemotherapy.
The GenusTospovirus: Emerging Bunyaviruses that Threaten Food Security (2016)

The genus Tospovirus is unique within the family Bunyaviridae in that it is made up of viruses that infect plants. Initially documented over 100 years ago, tospoviruses have become increasingly important worldwide since the 1980s due to the spread of the important insect vector Frankliniella occidentalis and the discovery of new viruses. As a result, tospoviruses are now recognized globally as emerging agricultural diseases. Tospoviruses and their vectors, thrips species in the order Thysanoptera, represent a major problem for agricultural and ornamental crops that must be managed to avoid devastating losses. In recent years, the number of recognized species in the genus has increased rapidly, and our knowledge of the molecular interactions of tospoviruses with their host plants and vectors has expanded. In this review, we present an overview of the genus Tospovirus with particular emphasis on new understandings of the molecular plant-virus and vector-virus interactions as well as relationships among genus members.
Structure of tetratellurium decachloro-μ-oxo-diniobate (1987)

Te 4 (Nb 2 Cl 10 O] cristallise dans le systeme triclinique avec le groupe d'espace P1. Affinement de la structure jusqu'a 0,0378. La structure se compose d'un cation carre Te 4 2+ et d'un anion Nb 2 OCl 10 2−
Genome‐wide DNA methylation in whole blood and CD16 + cells in response to chronic folic acid supplementation in women of child‐bearing age (817.1) (2014)

Folate is a key source of one‐carbon groups for DNA methylation; but studies on DNA methylation response to folic acid (FA) supplementation show inconsistent results. We hypothesize that measuring DNA methylation in whole blood (WB), which contains a mixture of distinct leukocyte cell types, may have confounded the results of previous studies. Therefore, the aim of this pilot study was to determine if a single cell type could serve as a more reliable epigenetic reporter. The study was performed in normal weight (BMI 18.5 – 24.9 kg/m 2 ) women (18 – 35 y; n = 12), with blood samples taken before and after eight weeks of supplementation with 800 ug/day of FA. CD16+ cells (CD16) were isolated using antibody‐bound magnetic beads. DNA methylation patterns from WB and CD16 cells were measured across &gt;485,000 CpG sites using the Infinium Human Methylation450 Bead Chip. For each CpG site, the proportion of DNA methylation that changed over the 8 week intervention was evaluated by fitting a separate linear model. Genome‐wide analysis indicated changes in 7887 vs. 8482 CpG sites in response to supplementation in WB and CD16, respectively; with DNA methylation decreased in 77.2% (WB) or 66.3% (CD16) of these sites. Results suggest that there are differences in methylation response in WB and CD16 after FA supplementation. The implication of these methylation differences are being explored in our on‐going gene enrichment analyses. Grant Funding Source : Funded in part by HATCH #GEO00706, #GEO00707 and the Obesity Initiative at the University of Georgia