gebhart/patrepeval huggingface dataset:
Predictors of DAPSA28 remission in patients with psoriatic arthritis initiating a first TNF inhibitor: results from 13 European registries (2023)

Baseline predictors of remission, response and adherence to TNFi therapy were identified, of which five were common for all three outcomes, indicating that the predictors emerging from our pooled cohort may be considered generalizable from country level to disease level.
The CDIO syllabus: a comparative study of expected student proficiency (2003)

Engineering students must graduate with command of a vast body of technical knowledge. They must possess personal, interpersonal and system-building skills to function in teams, and be prepared to produce products and systems. Their education must have been structured under a curriculum blending ability to combine technical expertise with ethical, innovative, philosophical and humanistic acumen. This paper describes a unique international collaboration among four universities to reform engineering education. The collaborators agreed to a statement of goals, which includes descriptions of knowledge, skills and attitudes vital to an effective education, and codifies proficiency levels expected of graduates. We developed and utilized unique stakeholder surveys both to validate our prototype and to determine desired proficiency levels. This collaboration resulted in The CDIO Syllabus, A Statement of Goals for Undergraduate Engineering Education. The syllabus is both a template and a process that can be used to customize the syllabus to others' programmes. It can define new educational initiatives/and be employed as the basis for rigorous assessment. This paper details how, with the input of industry, academia and others, we employed an engineering problem-solving paradigm to effect our redesign. It outlines the syllabus and the unique process employed to create it.
Strain-Release Electrophilic Activation via E-Cycloalkenones (2007)

UVA irradiation (ca. 350 nm) of a mixture of cyclic enones and nitrogen heterocycles leads to efficient formation of the 1,4-adducts in a variety of solvents, at room temperature. These reactions likely proceed through strained E-cycloalkenone intermediates, as suggested by low-temperature generation/trapping experiments monitored by 1H NMR. These results demonstrate that E-cycloalkenones are good electrophiles despite their known tendency to favor a conformation in which the carbonyl is not fully conjugated with the double bond.
Correlation effects and hidden spin-orbit entangled electronic order in parent and electron-doped iridates Sr$_2$IrO$_4$ (2017)

Analogs of the high-T$_c$ cuprates have been long sought after in transition metal oxides. Due to the strong spin-orbit coupling (SOC), the $5d$ perovskite iridates Sr$_2$IrO$_4$ exhibit a low-energy electronic structure remarkably similar to the cuprates. Whether a superconducting state exists as in the cuprates requires understanding the correlated spin-orbit entangled electronic states. Recent experiments discovered hidden order in the parent and electron doped iridates, some with striking analogies to the cuprates, including Fermi surface pockets, Fermi arcs, and pseudogap. Here, we study the correlation and disorder effects in a five-orbital model derived from the band theory. We find that the experimental observations are consistent with a $d$-wave spin-orbit density wave order that breaks the symmetry of a joint two-fold spin-orbital rotation followed by a lattice translation. There is a Berry phase and a plaquette spin flux due to spin procession as electrons hop between Ir atoms, akin to the intersite SOC in quantum spin Hall insulators. The associated staggered circulating $J_\text{eff}=1/2$ spin current can be probed by advanced techniques of spin-current detection in spintronics. This electronic order can emerge spontaneously from the intersite Coulomb interactions between the spatially extended iridium $5d$ orbitals, turning the metallic state into an electron doped quasi-2D Dirac semimetal with important implications on the possible superconducting state suggested by recent experiments.
Joint optical flow motion compensation and video compression using hybrid vector quantization (1999)

Summary form only given. We propose a video coding and delivery scheme which is geared towards low bit-rate and real-time performance requirements. We use a hybrid vector quantization scheme, with finite state wavelet-based hierarchical lookup vector quantization (FSWHVQ) for coding motion vectors, which embeds the Horn and Schunck optical flow algorithm in table-lookups, and uses lattice vector quantization (LVQ) for the prediction errors. This video coding scheme is both fast (table-lookups) and accurate (dense motion field), and avoids the blocking artifacts and poor prediction which plagues block coding schemes at low bit rates. For restricted image compression/transmission scenarios like teleconferencing, for which a good training set may be available, the FSWHVQ scheme may be viewed as storing as an internal representation in its lookup tables, a valid and complete model of the problem domain. Two row-wise lookups quantize the row-wise pixel values to give two table indices, Y0 and Y1, followed by a column-wise second-level table lookup, which quantizes the column-wise indices into one index, ZO. Horn and Schunck's optical flow method applies spatial and temporal derivative masks, e.g., of size 2/spl times/2, at corresponding spatial locations of the current and previous images. These mask applications are embedded inside table-lookups. The motion field averages (u/sub av/,v/sub av/), and the previous frame, I/sub t-I/, together comprise the "state", and are updated at each frame. The prediction errors are encoded with LVQ, as the error vectors are small (due to the accurate optical flow-based motion estimation), but more randomly distributed. It is possible to handle large displacements, by using the optical flow computations on the "smooth" bands in the DWT (discrete wavelet transform) domain.
Versatile Procedure of Multiple Introduction of 8-Aminomethylene Blue into Oligonucleotides (1995)

The coupling of 8-aminomethylene blue to oligonucleotides via poly-L-glutamic acid linker using carboxy-anchor groups will be described. The introduction of carboxy-anchor groups into oligonucleotides proceeds both during automated synthesis using 6-(ethoxycarbonyl)hexyl 1-O-phosphoramidite and by reaction of 5'-amino-functionalized oligonucleotides with succinic anhydride. O-(N-Succinimidyl)-1,1,3,3-tetramethyluronium tetrafluoroborate was used as activating reagent for binding of poly-L-glutamic acid to the carboxylated oligonucleotides. The successful 5'-carboxylation and poly-L-glutamic acid coupling were proven both by polyacrylamide gel electrophoreses and HPLC. 8-Aminomethylene blue in its leucoform was covalently coupled to the oligonucleotides in the presence of water soluble carbodiimide.
Switching dynamics and surface forces in thresholdless “V-shaped” switching ferroelectric liquid crystals (2003)

The electrostatic model of thresholdless V-shaped switching is able to explain the general low frequency (quasistatic) electro-optic behavior of smectic-C* ferroelectric liquid crystals (vFLCs). Here, dynamical equations based on the electrostatic model are developed which predict a vFLC cell's small-amplitude switching speed and which also show that a strongly amplitude-dependent switching speed is expected. A relationship between the switching time constants of analog vFLCs and of the faster, yet structurally similar, binary FLCs is found. The electrostatic model applies in the limit where the FLC's spontaneous polarization is large enough to completely overwhelm surface and elastic forces. This analysis suggests that, in many cases of practical interest, electrostatic energies may be low enough for surface forces to play an important role even when the director structure is strongly stiffened by a large polarization charge. It is shown that the addition of surface forces to the electrostatic model can improve agreement between the model and the observed dynamical response of vFLC cells.
The Emerging Interdependence of the Electric Power Grid & Information and Communication Technology (2015)

This paper examines the implications of emerging interdependencies between the electric power grid and Information and Communication Technology (ICT). Over the past two decades, electricity and ICT infrastructure have become increasingly interdependent, driven by a combination of factors including advances in sensor, network and software technologies and progress in their deployment, the need to provide increasing levels of wide-area situational awareness regarding grid conditions, and the promise of enhanced operational efficiencies. Grid operators’ ability to utilize new and closer-to-real-time data generated by sensors throughout the system is providing early returns, particularly with respect to management of the transmission system for purposes of reliability, coordination, congestion management, and integration of variable electricity resources such as wind generation.
A framework for recipe text interpretation (2014)

In this paper we describe a method for converting a recipe text into a meaning representation. The meaning representation is a flow graph, whose vertices are important word sequences in cooking (recipe named entity; NE) and edges denote relationships among them.
Positioning for NLOS Propagation: Algorithm Derivations and Cramer–Rao Bounds (2007)

Mobile positioning has drawn significant attention in recent years. Nonline-of-sight (NLOS) propagation error is the dominant error source in mobile positioning. Most previous research in this area has focused on NLOS identification and mitigation. In this paper, we investigate new positioning algorithms to take advantage of the NLOS propagation paths rather than canceling them. Based on a prior information about the NLOS path, a geometrical approach is proposed to estimate mobile location by using two NLOS paths. On top of this, the least-squares (LS)-based position estimation algorithm is developed to take multiple NLOS paths into account, and its performance in terms of root mean-square error (RMSE) is analyzed. A general LS algorithm considering both LOS and NLOS paths is also derived, and the maximum likelihood-based algorithm is presented to jointly estimate the mobile's and scatterers' positions. The Cramer-Rao lower bound on the RMSE is derived for the benchmark of the performance comparison. The performance of the proposed algorithms is evaluated analytically and is done via computer simulations. Numerical results demonstrate that the derived analytical results closely match the simulated results.
Comparison of Intracorporeal Reconstruction after Laparoscopic Distal Gastrectomy with Extracorporeal Reconstruction in the View of Learning Curve (2013)

Intracorporeal reconstruction after laparoscopic distal gastrectomy was feasible and safe, and the technique was stabilized after 20th case if the surgeon has sufficient experiences when we compared it with extracorporeal reconstruction.
Human amniotic fluid stem cells protect rat lungs exposed to moderate hyperoxia (2013)

Treatment with hAFS cells has a reparative potential through active involvement of cells in alveolarization and angiogenesis. A downstream paracrine action was also taken into account, in order to understand the immunodulatory response.
State-Space Vector Model of Linear Induction Motors Including End-Effects and Iron Losses—Part II: Model Identification and Results (2019)

This is the second part of an article, divided into two parts, dealing with the definition of a space-vector dynamic model of the linear induction motor (LIM) taking into consideration both the dynamic end-effects and the iron losses as well as the offline identification of its parameters. This second part is devoted to the description of an identification technique that has been suitably developed for the estimation of the electrical parameters of the LIM dynamic model accounting for both the dynamic end-effects and iron losses. Such an identification technique is strictly related to the state formulation of the proposed model and exploits genetic algorithms for minimizing a suitable cost function based on the processing of both the primary current and speed estimation errors. The proposed parameters' estimation technique has been validated experimentally on a suitably developed test set-up. It has been further validated by a finite element analysis model of the LIM.
Inheritance of DNA methylation differences in the mangrove Rhizophora mangle (2020)

Abstract The capacity to respond to environmental challenges ultimately relies on phenotypic variation which manifests from complex interactions of genetic and non-genetic mechanisms through development. While we know something about genetic variation and structure of many species of conservation importance, we know very little about the non-genetic contributions to variation. Rhizophora mangle is a foundation species that occurs in coastal estuarine habitats throughout the neotropics where it provides critical ecosystem functions, and is potentially threatened by climate change. Several studies have documented landscape level patterns of genetic variation in this species, but we know virtually nothing about the inheritance of non-genetic variation. To assess one type of non-genetic variation, we examined the patterns of DNA sequence and DNA methylation in maternal plants and offspring from natural populations of R. mangle from the Gulf Coast of Florida. We used a reduced representation bisulfite sequencing approach (epi-genotyping by sequencing or epiGBS) to address the following questions: a) What are the levels of genetic and epigenetic diversity in natural populations of R. mangle ? b) How are genetic and epigenetic variation structured within and among populations? c) How faithfully is epigenetic variation inherited? We found low genetic diversity but high epigenetic diversity from natural populations of maternal plants in the field and that a large portion (up to ~25%) of epigenetic differences among offspring grown in common garden was explained by maternal family. Therefore, epigenetic variation could be an important source of response to challenging environments in the genetically depauperate populations of this foundation species.
Active spectral imaging (2003)

With the ability to image a scene in tens to hundreds of spectral bands, multispectral and hyperspectral imaging sensors have become powerful tools for remote sensing. However, spectral imaging systems that operate at visible through nearinfrared wavelengths typically rely on solar illumination. This reliance gives rise to a number of limitations, particularly with regard to military applications. Actively illuminating the scene of interest offers a way to address these limitations while providing additional advantages. We have been exploring the benefits of using active illumination with spectral imaging systems for a variety of applications. Our laboratory setup includes multispectral and hyperspectral sensors that are used in conjunction with several laser illumination sources, including a broadband white-light laser. We have applied active spectral imaging to the detection of various types of military targets, such as inert land mines and camouflage paints and fabrics, using a combination of spectral reflectance, fluorescence, and polarization measurements. The sensor systems have been operated under a variety of conditions, both in the laboratory and outdoors, during the day and at night. Laboratory and outdoor tests have shown that using an active illumination source can improve target-detection performance while reducing false-alarm rates for both multispectral and hyperspectral imagers.
Large-Scale SLAM Building Conditionally Independent Local Maps: Application to Monocular Vision (2008)

<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> Simultaneous localization and mapping (SLAM) algorithms based on local maps have been demonstrated to be well suited for mapping large environments as they reduce the computational cost and improve the consistency of the final estimation. The main contribution of this paper is a novel submapping technique that does not require independence between maps. The technique is based on the intrinsic structure of the SLAM problem that allows the building of submaps that can share information, remaining <emphasis emphasistype="italic">conditionally independent</emphasis>. The resulting algorithm obtains local maps in constant time during the exploration of new terrain and recovers the global map in linear time after simple loop closures without introducing any approximations besides the inherent extended Kalman filter linearizations. The memory requirements are also linear with the size of the map. As the algorithm works in a covariance form, well-known data-association techniques can be used in the usual manner. We present experimental results using a handheld monocular camera, building a map along a closed-loop trajectory of 140 m in a public square, with people and other clutter. Our results show that the combination of conditional independence, which enables the system to share the camera and feature states between submaps, and local coordinates, which reduce the effects of linearization errors, allow us to obtain precise maps of large areas with pure monocular SLAM in real time. </para>
Primitive Recursion and State Machines (2009)

Methods for specifying Moore type state machines (transducers) ab-stractly via primitive recursive functions and for definining parallel com-position via simultaneous primitive recursion are discussed. The method is mostly of interest as a concise and convenient way of working with the complex state systems found in computer programming and engi-neering, but a short section indicates connections to algebraic automata theory and the theorem of Krohn and Rhodes. 1
Soybean and sunflower oil performance in a diesel engine. (1986)

ABSTRACT THE performance of a direct injection diesel engine operating on mechanically expelled-unrefined soybean oil and sunflower oil blended with number 2 diesel fuel on a 25:75 v/v basis was evaluated. The power remained constant throughout 200 h of operation. Excessive carbon deposits on all combustion chamber parts precludes the use of these fuel blends, at least in this engine and under the specified EMA operating conditions.
Palliation of malignant aerodigestive fistulae with self-expanding metallic stents (2007)

Malignant aerodigestive fistulae are rare but devastating sequelae of thoracic cancers, most commonly associated with esophageal cancer. Survival following development of a malignant aerodigestive fistula is measured in weeks. Palliation is the primary goal of therapy and to this end, we report the use of self-expanding metallic stents (SEMS) as treatment. Between May 1999 and January 2004, 12 patients were treated for malignant aerodigestive fistulae. The underlying diagnosis was esophageal cancer for 10 patients, and non-small cell lung cancer for two others. All patients were symptomatic and fistulae were diagnosed by esophagoscopy in seven, bronchoscopy in two, and esophagram in three. Seven covered Wallstents (seven esophageal) and eight covered Ultraflex (five tracheal and three esophageal) were used. A single stent was placed in eight patients (seven esophageal and one tracheal). Three patients required esophageal and tracheal stents and one patient needed two tracheal stents. General anesthesia was required in 50% of the patients. There were no procedure-related complications. Symptoms were palliated in 100% of patients and oral intake was reinstituted in 42% (5/12). All the patients were discharged from hospital after SEMS placement and one patient returned for an uneventful tracheal stent replacement secondary to mucus impaction 2 months later. SEMS placement is an effective strategy to palliate malignant aerodigestive fistulae. Complications are rare and symptoms are alleviated in most patients.
Tint fill (1979)

To fill a connected area of a digital image is to change the color of all and only those pixels in the area. Fill algorithms for areas defined by sharp boundaries (e.g., a white area surrounded by a black curve) have been implemented at several color computer graphics installations. This paper presents an algorithm for the more difficult problem of filling areas with shaded boundaries (e.g., a white area surrounded by a curve consisting of several shades of gray). These images may arise from digitizing photographs or line drawings with a scanning video camera, or they may be generated by programs which produce antialiased line segments or dekink black-and-white images. When an area in such an image is to be filled with a new color, it is desirable to have the fill algorithm understand the shaded edges and maintain the shading with shades of the new color instead of the old. The tint fill algorithm presented here accomplishes this task. Its name arises from its ability to change only the tint (hue and saturation) of a pixel, leaving the value (blackness) unchanged. Although the algorithm was motivated by and is written in terms of color, it has a more general interpretation, which is also presented.
Strategic Planning at Indiana University (2014)

You are likely aware that IU is in the process of drafting and implementing a system-wide Bicentennial Strategic Plan based on recent campus strategic plans. I hope everyone provided input. There is a lot of planning going on right now. Both the Robert H. McKinney School of Law and the Ruth Lilly Law Library updated their strategic plans in the last year or so. Additionally, those of us serving on promotion and tenure committees advise librarians going up for promotion or tenure to create plans to meet the criteria and to demonstrate the upward trajectory expected by the reviewing committees. The planning process at each of these levels is unique, but they share certain commonalities.