gebhart/patrepeval huggingface dataset:
New Correction Methods for Nonorthogonality and Amplitude Mismatch of Angle Position Sensor by Using Atan2-Function (2020)

This article introduces a new method to correct the nonorthogonality of an angle position sensor based on Atan2- function without determination of the phase shift. Furthermore, to compensate the nonorthogonality and amplitude mismatch a more accurate method is proposed by using principal component analysis. Moreover, the advantages and disadvantages of both methods are discussed, compared to the conventional methods.
The National Education Supercomputer Program: (1994)

No abstract available for this article.
Security Games with Incomplete Information (2009)

We study two-player security games which can be viewed as sequences of nonzero-sum matrix games played by an attacker and a defender. At each stage of the game iterations, the players make imperfect observations of each other's previous actions. The underlying decision process can be viewed as a fictitious play (FP) game, but what differentiates this class from the standard one is that the communication channels that carry action information from one player to the other, or the sensor systems, are error prone. Two possible scenarios are addressed in the paper: (i) if the error probabilities associated with the sensor systems are known to the players, then our analysis provides guidelines for each player to reach a Nash equilibrium (NE), which is related to the NE of the underlying static game; (ii) if the error probabilities are not known to the players, then we study the effect of observation errors on the convergence to the NE and the final outcome of the game. We discuss both the classical FP and the stochastic FP, where for the latter the payoff function of each player includes an entropy term to randomize its own strategy, which can be interpreted as a way of concealing its true strategy.
Metabolic Engineering of Cofactor F420 Production in Mycobacterium smegmatis (2010)

Cofactor F(420) is a unique electron carrier in a number of microorganisms including Archaea and Mycobacteria. It has been shown that F(420) has a direct and important role in archaeal energy metabolism whereas the role of F(420) in mycobacterial metabolism has only begun to be uncovered in the last few years. It has been suggested that cofactor F(420) has a role in the pathogenesis of M. tuberculosis, the causative agent of tuberculosis. In the absence of a commercial source for F(420), M. smegmatis has previously been used to provide this cofactor for studies of the F(420)-dependent proteins from mycobacterial species. Three proteins have been shown to be involved in the F(420) biosynthesis in Mycobacteria and three other proteins have been demonstrated to be involved in F(420) metabolism. Here we report the over-expression of all of these proteins in M. smegmatis and testing of their importance for F(420) production. The results indicate that co-expression of the F(420) biosynthetic proteins can give rise to a much higher F(420) production level. This was achieved by designing and preparing a new T7 promoter-based co-expression shuttle vector. A combination of co-expression of the F(420) biosynthetic proteins and fine-tuning of the culture media has enabled us to achieve F(420) production levels of up to 10 times higher compared with the wild type M. smegmatis strain. The high levels of the F(420) produced in this study provide a suitable source of this cofactor for studies of F(420)-dependent proteins from other microorganisms and for possible biotechnological applications.
Micro valve system for individual cell transportation in microfluidic chip (2009)

Recently, micro valves to control some kinds of fluids in channels in a microchip have been developed. Now we pay attention to in-chip somatic cell cloning with microfluidic technology. There are some steps, cell supply, cutting, sorting, coupling, fusion and so on, for this work. And we focused on a cell supply system spending cells one by one in microfluidic chip, and attempt to transport an individual cell to objective course by the control of pressure valves. Here, we made three kinds valves, a) open channel 2-layer valve, b) open channel 3-layer valve, and c) close channel 2-layer valve. We compare these valves about interception condition of micro channel flow and time to take for open/close. And then we evaluated them with suitable for the smooth cell transportation by these comparisons.
The needle found!!! Trinucleotide repeat expansion in the Huntington's disease gene (1993)

Journal Article The needle found!!! Trinucleotide repeat expansion in the Huntington's disease gene Get access Huntington F. Willard Huntington F. Willard Department of Genetics, Center for Human Genetics, Case Western Reserve University School of MedicineCleveland, OH 44106, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar Human Molecular Genetics, Volume 2, Issue 5, May 1993, Pages 497–498, https://doi.org/10.1093/hmg/2.5.497 Published: 01 May 1993
Introduction (2004)

Thousands of tiny low-power devices spread over large physical spaces collaboratively monitor the environment, guide vehicles, and predict potential faults in buildings, bridges, roads, and rails.
Opportunities and challenges of 3D NAND scaling (2013)

3D NAND is attracting increasing attention as a NAND scaling solution. In 3D NAND, the physical cell size is decoupled from the effective cell size by stacking multiple tiers. This enables effective NAND cell size scaling without degrading cell performance and reliability. However, 3D process integration could introduce new sources of cell degradation. This paper will discuss the opportunities and challenges of 3D NAND scaling.
(8‐Naphthalen‐1‐ylmethyl‐4‐oxo‐1‐phenyl‐1,3,8‐triaza‐spiro[4.5]dec‐3‐yl)‐acetic acid methyl ester (NNC 63‐0532) is a novel potent nociceptin receptor agonist (2000)

Spiroxatrine was identified as a moderately potent (K:(i)=118 nM) but non-selective agonist at the human nociceptin/orphanin FQ receptor, ORL1. This compound was subject to chemical modification and one of the resulting compounds, (8-naphthalen-1-ylmethyl-4-oxo-1-phenyl-1,3,8-triaza-s piro[4. 5]dec-3-yl)-acetic acid methyl ester (NNC 63-0532) was shown to have high affinity for ORL1 (K:(i)=7.3 nM). NNC 63-0532 showed only moderate affinity for the following receptors (K:(i) values in parentheses): mu-opioid (140 nM), kappa-opioid (405 nM), dopamine D(2S) (209 nM), dopamine D(3) (133 nM) and dopamine D(4.4) (107 nM) out of 75 different receptors, ion-channels and transporters. In functional assays, NNC 63-0532 was shown to be an agonist at ORL1 (EC(50)=305 nM), a much weaker agonist at the mu-opioid receptor (EC(50)>10 microM) and an antagonist or weak partial agonist at dopamine D(2S) (IC(50)=2830 nM). Thus, NNC 63-0532 is a novel non-peptide agonist with approximately 12 fold selectivity for ORL1 and may be useful for exploring the physiological roles of this receptor owing to its brain-penetrating properties.
Genome-block expression-assisted association studies discover malaria resistance genes in Anopheles gambiae (2013)

The malaria parasite-resistance island (PRI) of the African mosquito vector, Anopheles gambiae, was mapped to five genomic regions containing 80 genes, using coexpression patterns of genomic blocks. High-throughput sequencing identified 347 nonsynonymous single-nucleotide polymorphisms within these genes in mosquitoes from malaria-endemic areas in Kenya. Direct association studies between nonsynonymous single-nucleotide polymorphisms and Plasmodium falciparum infection identified three naturally occurring genetic variations in each of three genes (An. gambiae adenosine deaminase, fibrinogen-related protein 30, and fibrinogen-related protein 1) that were associated significantly with parasite infection. A role for these genes in the resistance phenotype was confirmed by RNA interference knockdown assays. Silencing fibrinogen-related protein 30 increased parasite infection significantly, whereas ablation of fibrinogen-related protein 1 transcripts resulted in mosquitoes nearly free of parasites. The discovered genes and single-nucleotide polymorphisms are anticipated to be useful in the development of tools for malaria control in endemic areas in Africa.
Degradation mechanism of nefopam in solution under stressed storage conditions. (1990)

Nefopam, in pH 2.0 and pH 9.0 solutions, was forcibly degraded at 90 +/- 0.2 degrees C for 60 days. At least eight degradation products from the above solutions were collected from a reverse-phase high performance liquid chromatographic (HPLC) system with a C18 semipreparative column. Some minor peaks were considered insignificant, and no attempt was made to collect and identify their structures. The collected eluents under each major peak were further purified by extraction with methylene chloride from alkaline solutions. Proton nuclear magnetic resonance and fast atom bombardment mass spectroscopy were used to characterize the chemical properties of these degradates. The chemical structures of the major degradation products were proposed as (B) or (C) 2,3-dihydro-2(2'-hydroxyethyl)-N-methyl-1-phenyl-isoindole; (D) or (E) 1-hydroxy-3,4,5,6-tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine++ +; (F) 2-(N-(2-hydroxyethyl)-N-methylaminomethyl) benzhydrol; (G) 2-(N-(2-hydroxyethyl)-N-methylaminoethyl) benzophenone; (H) 1-hydroxy-3,4,5,6-tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine++ +, where B and C, D and E, are diasteromers. The possible pathways by which the nefopam degradation proceeded in acidic and basic solutions is postulated as Schemes I and II, respectively. The initial ring-opening process at the site of ether linkage appears to be the rate-determining step of degradation in both acidic and basic solutions.
General Access to Aminobenzyl‐o‐carboranes as a New Class of Carborane Derivatives: Entry to Enantiopure Carborane–Amine Combinations (2009)

The convenient synthesis of original aminobenzyl-o-carboranes, which represent a new class of nitrogenated carborane derivatives, is described. These novel compounds have been efficiently prepared starting from commercially available aromatic aldehydes and monosubstituted o-carboranes via carboranyl alcohols and chlorides as intermediates. The key step of this methodology is a selective nucleophilic amination under mild conditions that allows the formation of the expected amines while limiting the partial deboronation of the carborane cluster. This general strategy has been applied to the preparation of a wide variety of aminobenzyl-o-carboranes. The extension of this pathway to the synthesis of enantiopure carborane-amine combinations is also described.
FIELD MEASUREMENT OF TRANSFER LENGTH (1996)

Five aramid fiber reinforced plastic (AFRP) and five carbon fiber reinforced plastic (CFRP) beams, cast in adjacent 122 m beds in a commercial pretensioning facility, were field instrumented to determine their transfer length. The rods were jacked to 55% and 60% of the characteristic strength of the AFRP and CFRP material respectively. A total of twelve strain gages - five at each end and two in the middle - were attached to the top surface of the beams. The prestressing force in the rods was monitored using load cells located at the live and dead ends. Following release, concrete strains were recorded by a computerized data acquisition system. Reconciliation of test results with finite element analysis indicated that the transfer lengths for the sand coated AFRP rod and the grit coated CFRP rod were very similar - equal to about 30 times the rod diameter - in broad agreement with results reported previously.
In vivo monitoring of volatile metabolic trajectories enables rapid diagnosis of influenza A infection (2021)

We report that influenza A virus infection induces changes in odor traits that could be captured by real-time high-resolution mass spectrometry in a living mouse model. The most striking changes in the volatile metabolites may be associated mostly to glyoxylate/dicarboxylate metabolism.
Hydrosilylation Catalysis by C2-Symmetric Bis(silylamido) Complexes of Yttrium (1999)

The yttrium hydride {[DADMB]YH(THF)}2 (2; DADMB = 2,2‘-bis(tert-butyldimethylsilylamido)-6,6‘-dimethylbiphenyl), conveniently generated in situ from [DADMB]YMe(THF)2 (1), is an active olefin hydrosilylation catalyst. This system represents the first use of a d0 metal complex with non-Cp ligands in the catalytic hydrosilylation of olefins. Studies of the reactivity and regio- and enantioselectivity for various olefins and silanes are presented. High preference for terminal addition in the case of aliphatic olefins is observed, while aromatic olefins exhibit preference for 2,1-addition. Both primary and secondary silanes have been employed. Preliminary studies of the enantioselectivity of the chiral catalyst show that 90% ee can be achieved in the hydrosilylation of norbornene with PhSiH3. Kinetic studies support a mechanism consistent with the generally accepted one for hydrosilylation catalyzed by early transition metal species, involving rapid olefin insertion into a Y−H bond followed by a Si−C bond-forming σ-bond metathesis of the resulting yttrium alkyl with silane.
Valve repair for traumatic tricuspid regurgitation (1996)

Since post-traumatic tricuspid regurgitation is effectively correctable with reparative techniques, early operation is recommended to relieve symptoms and to prevent right ventricular dysfunction.
Dagstuhl Seminar on Robust Query Processing – Summary and Abstracts Collection (2011)

Dagstuhl seminar 10381 on robust query processing (held 19.09.10 – 24.09.10) brought together a diverse set of researchers and practitioners with a broad range of expertise for the purpose of fostering discussion and collaboration regarding causes, opportunities, and solutions for achieving robust query processing. The seminar strove to build a unified view across the loosely-coupled system components responsible for the various stages of database query processing. Participants were chosen for their experience with database query processing and, where possible, their prior work in academic research or in product development towards robustness in database query processing. In order to pave the way to motivate, measure, and protect future advances in robust query processing, seminar 10381 focused on developing tests for measuring the robustness of query processing. In these proceedings, we first review the seminar topics, goals, and results, then present abstracts or notes of some of the seminar break-out sessions. We also include, as an appendix, the robust query processing reading list that was collected and distributed to participants before the seminar began, as well as summaries of a few of those papers that were contributed by some participants.
Techniques and circuits for ultra-efficient energy harvesting sensor nodes (2021)

Sensor nodes play increasingly important role in various enterprises like agriculture, transport, defence etc. As the number of sensor nodes increase, their energy consumption, running and maintenance costs become detrimental to their implementation. Energy harvesting is an alternative to tethered or battery-powered sensor nodes which holds the promise of long-term sustainable operation. The energy available however, is limited and decreases further as sensor nodes become smaller. A small size also calls for tighter and possibly, monolithic integration. The limited available energy and small form-factor necessitates high energy efficiency in sensor nodes that must be guaranteed at design time. While integrated circuit (IC) design uses well-characterized device models for simulation, energy harvesters rarely have accurate models upon which to draw for circuit design. This research explores development of models for small cm2 photovoltaic cells by first characterizing them in real-world conditions and develop simulation models to enable IC design. The models are then used to investigate power conversion circuits and techniques for improving energy efficiency of sensor nodes. In this thesis, a compact and low-cost characterization scheme is used to develop a simulation model for photovoltaic cell which shows good correlation with measurements. The results of this work show the potential to improve sensor node design margining by as much as 16×. Holistic system solutions are then explored to maximize utilization of harvested energy with efficient power conversion resulting in a 30% increase in computation cycles in the sensor node. Ultra-low-power rail monitor and oscillator circuits are also presented. The rail monitor exploits state-awareness to provide the best-reported balance in response speed and power consumption. The oscillator uses sub-cycle comparator duty-cycling to provide the lowest energy per cycle in the smallest area while exhibiting comparable line and temperature sensitivities. This research has resulted two journals, three peerreviewed conference papers and three granted patents
Development of Monitoring System on Methane Hydrate Production (2008)

From 2001, the Japanese government has had a national project, conducted by Research Consortium for Methane Hydrate Resources in Japan, which has been promoting methane hydrate exploitation under the seabed in the deep sea of more than 1000 m depth in Japanese EEZ. This paper briefly describes the development of the monitoring technology, by one of the R&D sub-group of Environmental Impact Assessment Group of the Consortium that is conducted by Engineering Advancement Association of Japan, including both sensor technology and integration technology of the monitoring system in the deep sea on some possible factors which can badly affect to the environment around the methane hydrate production area in the future. Regarding sensor technology, we have had great efforts to develop high-performance sensors for dissolved methane and seafloor displacement, which we thought had not been well developed during our pre-investigation several years ago. As to integration of the total monitoring system, at first, we studied well what items to monitor, how to monitor and how accurate to read. According to the results, we studied the existing related technologies including installation units i.e. mooring type and AUV, electric power supply, data transportation, installation/removal method and so on, so that we could successfully reach some conclusion on total concept of the integrated monitoring system. Based on the concept, we also successfully completed the study on a necessary integrated monitoring system that shall be deployed with the well-developed sensors at the ocean production trial that is planned to carry out in the future.
Investigation of an Eight-Week Neuromuscular Training Intervention on Biomechanical Parameters of the Lower Quarter in Adolescent Female Soccer Players (2022)

Purpose: Mounting evidence supports the implementation of neuromuscular training (NMT) interventions to improve biomechanical profiles for prevention of musculoskeletal injury in dynamic pivoting athletes. Research has demonstrated there is a clear link between functional movement behavior and vulnerability to injury. However, there is limited research examining the capacity of NMT to positively influence pathomechanical movement behavior. This investigation assessed the strength, balance, and functional biomechanics of uninjured adolescent female athletes following an eight-week NMT intervention, which was conducted in order to expand upon research aimed at injury prevention in the lower quarter. Methods: 37 female soccer players ages 10 -15 participated. Hip strength was measured with hand dynamometry, and single-leg stance modified balance (SLS M ) was measured in multiple conditions. A 3-Dimensional Dynamic Movement Assessment (3D-DMA) system assessed lower quarter joint excursion during select functional loading tasks. Participants completed an 8-week, 16-session NMT intervention followed by repeated measurements. Results: Following the intervention, significant improvements were found in: hip abduction strength bilaterally (p = 0.000), hip extension strength bilaterally (p = 0.000), SLS M in eyes-closed condition bilaterally (p = 0.000), and DMA functional outcomes in the Full Squat Test (p = 0.019), Step-Up Test (p = 0.007), Single-Leg Squat Test (p = 0.000), and Single-Leg Hop Test (p = 0.000). Conclusions: These data indicate an 8-week NMT intervention is sufficient to elicit positive neuromuscular adaptations in the lower quarter associated with pathomechanical loading patterns. Such adaptations support improved function across a diversity of complex sport-related movements. More research is needed to further devel-
A two-stage modeling and simulation process for web-based modeling and simulation (2002)

The area of web-based simulation has thrived primarily on novel methods for executing models, with contributions to both client and server side applications based in Java and other web-accessible languages. However, there has not been a commensurate degree of research in the area of model design, and in the dissemination of models over the web to support discrete event simulation. For a web-based modeling framework to succeed, that framework must support at least one markup language for specifying model content, as well as methods for converting the markup to a programming language, which is used to simulate the model. We present such a framework, called rube , and focus on a two-stage translation process from one markup language (MXL) to another (DXL), with a final process to create either Java or Javascript target code. This framework has allowed us to leverage the eXtensible Markup Language (XML) for capturing the dynamics of a small number of key modeling types commonly found in computer simulation applications. Our approach allows us to achieve customization of a model's appearance, as well to obtain the transformative benefits of specifying model information within an XML format.
Sulfuric acid nucleation: power dependencies, variation with relative humidity, and effect of bases (2012)

Abstract. Nucleation of particles composed of sulfuric acid, water, and nitrogen base molecules was studied using a continuous flow reactor. The particles formed from these vapors were detected with an ultrafine condensation particle counter, while vapors of sulfuric acid and nitrogen bases were detected by chemical ionization mass spectrometry. Variation of particle numbers with sulfuric acid concentration yielded a power dependency on sulfuric acid of 5 ± 1 for relative humidities of 14–68% at 296 K; similar experiments with varying water content yielded power dependencies on H2O of ~7. The critical cluster contains about 5 H2SO4 molecules and a new treatment of the power dependency for H2O suggests about 12 H2O molecules for these conditions. Addition of 2-to-45 pptv of ammonia or methyl amine resulted in up to millions of times more particles than in the absence of these compounds. Particle detection capabilities, sulfuric acid and nitrogen base detection, wall losses, and the extent of particle growth are discussed. Results are compared to previous laboratory nucleation studies and they are also discussed in terms of atmospheric nucleation scenarios.