gebhart/patrepeval huggingface dataset:
Stabilized Acoustic Levitation of Dense Materials Using a High-Powered Siren (1982)

Stabilized acoustic levitation and manipulation of dense (e.g., steel) objects of 1 cm diameter, using a high powered siren, was demonstrated in trials that investigated the harmonic content and spatial distribution of the acoustic field, as well as the effect of sample position and reflector geometries on the acoustic field. Although further optimization is possible, the most stable operation achieved is expected to be adequate for most containerless processing applications. Best stability was obtained with an open reflector system, using a flat lower reflector and a slightly concave upper one. Operation slightly below resonance enhances stability as this minimizes the second harmonic, which is suspected of being a particularly destabilizing influence.
Arithmetic operators for on-the-fly evaluation of TRNGs (2009)

Many cryptosystems embed a high-quality true random number generator (TRNG). The randomness quality of a TRNG output stream depends on its implementation and may vary due to various changes in the environment such as power supply, temperature, electromagnetic interferences. Attacking TRNGs may be a good solution to decrease the security of a cryptosystem leading to lower security keys or bad padding values for instance. In order to protect TRNGs, on-the-fly evaluation of their randomness quality must be integrated on the chip. In this paper, we present some preliminary results of the FPGA implementation of functional units dedicated to statistical tests for on-the-fly randomness evaluation. In the entropy test the evaluation of the harmonic series at some ranks is required. Usually its approximation is costly. We propose a multiple interval polynomial approximation. The decomposition of the whole domain into small sub-intervals leads to a good trade-off between the degree of the polynomial (i.e. multipliers cost) and the memory resources required to store the coefficients for all sub-intervals.
A combined approach to multi-label multi-task learning (2012)

In this paper, we present a method for jointly learning r >; 1 similar classification tasks. We consider a set of classification tasks whose relevant features may have some overlap. This potential overlap encourages the idea of learning tasks simultaneously. Our method is based on the idea of using two regularizers which control the underlying structure of the model from completely unrelated tasks to practically the same tasks. We show that this problem is equivalent to a convex optimization problem. Our results on simulated and real data sets demonstrate that our proposed method dramatically improves the performance on partially related tasks in comparison to independently learning the tasks or other multi-task approaches.
DC Link Stabilization of Single-Phase Power Factor Correction by Using Differential Flatness-Based Control Approach (2016)

International audience
Simple prediction of COVID-19 convalescent plasma with high levels of neutralization antibodies (2022)

Background: Hyperimmune convalescent COVID-19 plasma (CCP) containing anti-SARS-CoV-2 neutralizing antibodies (NAbs) was proposed as a therapeutic option for patients early in the new coronavirus disease pandemic. The efficacy of this therapy depends on the quantity of neutralizing antibodies (NAbs) in the CCP units, with titers &gt; 1:160 being recommended. The standard neutralizing tests (NTs) used for determining appropriate CCP donors are technically demanding and expensive and take several days. We explored whether they could be replaced by high-throughput serology tests and a set of available clinical data. Methods: Our study included 1302 CCP donors after PCR-confirmed COVID-19 infection. To predict donors with high NAb titers, we built four (4) multiple logistic regression models evaluating the relationships of demographic data, COVID-19 symptoms, results of various serological testing, the period between disease and donation, and COVID-19 vaccination status. Results: The analysis of the four models showed that the chemiluminescent microparticle assay (CMIA) for the quantitative determination of IgG Abs to the RBD of the S1 subunit of the SARS-CoV-2 spike protein was enough to predict the CCP units with a high NAb titer. CCP donors with the respective results &gt;6000 AU/ml SARS-CoV-2 IgG had an 80% probability of attaining high NAb titers. Including additional variables such as donor demographics, clinical symptoms, or time of donation into a particular predictive model did not significantly increase its sensitivity and specificity. Conclusion: A simple quantitative serological determination of anti-SARS-CoV-2 antibodies alone is satisfactory for efficiently predicting CCP donors with high titer NAbs.
A method for attosecond pulse measurement (2000)

Summary form only given. There exist a number of proposals for the generation of attosecond pulse trains or single attosecond pulses. Unfortunately, measurement of the duration of these pulses has not been possible to date. Currently used techniques are either limited by the pulse duration of the laser pulse, as in multiphoton cross correlation measurements, or by insufficient cross section, as in two photon absorption measurements. We present a novel technique for the measurement of attosecond pulses based on cross correlation between a strong laser pulse and an attosecond pulse in a noble gas. The method fundamentally differs from previously performed multiphoton cross correlation measurements, the resolution of which is limited by the laser pulse duration. In contrast, the resolution limit of our method lies at about one tenth of the optical period of the laser pulse. We investigate the method by numerically solving the 3-dimensional Schrodinger equation for a He/sup +/ ion.
Involvement of Apolipoprotein E in Excess Fat Accumulation and Insulin Resistance (2006)

Although apolipoprotein E (apoE) is well known to play a major role in lipid metabolism, its role in glucose and energy homeostasis remains unclear. Herein, we established apoE-deficient genetically obese Ay (apoE(-/-);Ay/+) mice. ApoE deficiency in Ay mice prevented the development of obesity, with decreased fat accumulation in the liver and adipose tissues. ApoE(-/-);Ay/+ mice exhibited better glucose tolerance than apoE(+/+);Ay/+ mice. Insulin tolerance testing and hyperinsulinemic-euglycemic clamp study revealed marked improvement of insulin sensitivity, despite increased plasma free fatty acid levels. These metabolic phenotypes were reversed by adenoviral replenishment of apoE protein, indicating circulating apoE to be involved in increased adiposity and obesity-related metabolic disorders. Uptake of apoE-lacking VLDL into the liver and adipocytes was markedly inhibited, but adipocytes in apoE(-/-);Ay/+ mice exhibited normal differentiation, suggesting that apoE-dependent VLDL transport is involved in the development of obesity, i.e., surplus fat accumulation. Interestingly, apoE(-/-);Ay/+ mice exhibited decreased food intake and increased energy expenditure. Pair-feeding experiments indicate these phenomena to both contribute to the obesity-resistant phenotypes associated with apoE deficiency. Thus, apoE is involved in maintaining energy homeostasis. ApoE-dependent excess fat accumulation is a promising therapeutic target for the metabolic syndrome.
STUDIES ON THE TOXIC INTERACTION BETWEEN MONENSIN AND TIAMULIN IN RATS: TOXICITY AND PATHOLOGY (2000)

The characteristics of the toxic interaction between monensin and tiamulin were investigated in rats. A three-day comparative oral repeated-dose toxicity study was performed in Phase I, when the effects of monensin and tiamulin were studied separately (monensin 10, 30, and 50 mg/kg or tiamulin 40, 120, and 200 mg/kg body weight, respectively). In Phase II, the two compounds were administered simultaneously to study the toxic interaction (monensin 10 mg/kg and tiamulin 40 mg/kg b.w., respectively). Monensin proved to be toxic to rats at doses of 30 and 50 mg/kg. Tiamulin was well tolerated up to the dose of 200 mg/kg. After combined administration, signs of toxicity were seen (including lethality in females). Monensin caused a dose-dependent cardiotoxic effect and vacuolar degeneration of the skeletal muscles in the animals given 50 mg/kg. Both compounds exerted a toxic effect on the liver in high doses. After simultaneous administration of the two compounds, there was a mild effect on the liver (females only), hydropic degeneration of the myocardium and vacuolar degeneration of the skeletal muscles. The alteration seen in the skeletal muscles was more marked than that seen after the administration of 50 mg/kg monensin alone.
Palladium-Catalyzed Heterogeneous Hydrogenation (2005)

The authors present a concise discussion of heterogeneous Pd-catalyzed hydrogenation and a brief discussion of Pd-catalyzed homogeneous hydrogenation. The chapter explores the synthetic methods developed for the conjugate reduction of α, β-unsaturated carbonyl compounds focusing on those methodologies that involve the use of palladium catalysts. Three sections are considered: catalytic hydrogenation over palladium catalysts; Pd-catalyzed reductions with group 14 metal hydrides; and Pd-catalyzed reductions with other hydrogen donors. Attention is given to selective alkene and alkyne isomerization reactions of synthetic interest. A limited number of studies on the Pd-catalyzed isomerization of monoenes including its mechanistic aspects is featured. A discussion of hydrogen transfer hydrometallation promoted by Pd catalysts is included. Bis-silylation, silylboration, and borylstannation of alkynes and alkenes are reviewed. The authors explore the syn-heteropalladation of carbon–carbon unsaturated compounds with group 15, 16 and 17 heteroatom compounds.
High-Speed Fixed Memories Using Large-Scale Integrated Resistor Matrices (1968)

Abstract—A new READ-only memory design using resistive linear coupling has been developed for high-speed operation. Cost, reliability, and high-speed considerations lead to the use of large-scale integrated resistor matrices. Principles of operation, signal-to-noise ratios, circuits, and memory organization are discussed. The design and fabrication of large-scale integrated resistor matrices is emphasized. Cycle times as fast as 50 and 100 ns have been achieved on 256-word 80-bit modules.
Chromosome Numbers of Cultivated Junipers (1979)

Of 31 cultivars and five varieties in six species of Juniperus, 20 are diploids (2n = 22); three, triploids; 13, tetraploids. Juniperus communis, J. horizontalis, and J. sabina are diploid; and J. squamata is tetraploid. Cultivars of J. chinensis are diploid, triploid, and tetraploid, and of J. virginiana, diploid and triploid. The triploids, J. chinensis `Blue Cloud' and `Hetzii' and J. virginiana `Grey Owl,' appear to be hybrids between the tetraploid J. chinensis `Pfitzeriana' and diploid J. virginiana `Glauca.'
ChemInform Abstract: Copper‐Catalyzed Condensation of Imines and α‐Diazo‐β‐dicarbonyl Compounds: Modular and Regiocontrolled Synthesis of Multisubstituted Pyrroles. (2016)

Abstract In the presence of a copper(II) catalyst, enolizable imines bearing various N‐substituents and α‐diazo‐β‐ketoesters undergo denitrogenative and dehydrative condensation to afford highly substituted pyrroles with exclusive regioselectivity.
X-Ray Sensitivity and DNA Synthesis in Synchronous Populations of HeLa Cells (1963)

Inhibition with either 5-fluorodeoxyuridine or deoxyadenosine for specified periods during the division cycle of the HeLa S3 cell shows that the mid-interphase peak in sensitivity occurs just before DNA replication begins. Sensitivity subsequently decreases only after synthesis of DNA is resumed. One interpretation of the relation between fluctuations in sensitivity and in DNA synthesis is that the lethal radiation damage to these cells occurs in DNA.
ChemInform Abstract: Synthesis of 1,1‐Disubstituted Olefins via Catalytic Alkyne Hydrothiolation/Kumada Cross‐Coupling. (2009)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Comparative Genomic Hybridization in the Study of Human Disease (2006)

Abstract Alterations in DNA copy number are frequently involved in developmental abnormalities and cancer. Microarray‐based comparative genomic hybridization can detect and map these alterations with high resolution throughout the genome.
Associations of Heart Rate With Inflammatory Markers Are Modulated by Gender and Obesity in Older Adults (2014)

Faster HR is associated with proinflammatory state in elderly patients; this association seems to be limited to women with higher BMI.
Adult DRG Stem/Progenitor Cells Generate Pericytes in the Presence of Central Nervous System (CNS) Developmental Cues, and Schwann Cells in Response to CNS Demyelination (2015)

It has been proposed that the adult dorsal root ganglia (DRG) harbor neural stem/progenitor cells (NPCs) derived from the neural crest. However, the thorough characterization of their stemness and differentiation plasticity was not addressed. In this study, we investigated adult DRG-NPC stem cell properties overtime, and their fate when ectopically grafted in the central nervous system. We compared them in vitro and in vivo to the well-characterized adult spinal cord-NPCs derived from the same donors. Using micro-dissection and neurosphere cultures, we demonstrate that adult DRG-NPCs have quasi unlimited self-expansion capacities without compromising their tissue specific molecular signature. Moreover, they differentiate into multiple peripheral lineages in vitro. After transplantation, adult DRG-NPCs generate pericytes in the developing forebrain but remyelinating Schwann cells in response to spinal cord demyelination. In addition, we show that axonal and endothelial/astrocytic factors as well astrocytes regulate the fate of adult DRG-NPCs in culture. Although the adult DRG-NPC multipotency is restricted to the neural crest lineage, their dual responsiveness to developmental and lesion cues highlights their impressive adaptive and repair potentials making them valuable targets for regenerative medicine.
Fate of [14C/3H]Emamectin Benzoate in Cabbage. 1. Extractable Residues (1997)

Cabbage, after treatment with eight weekly applications of the semisynthetic avermectin at a 0.015 lb a.i./acre (1×) or a 5× rate, was collected at preharvest intervals (PHI) from 2 h to 10 d. For foliage at 2 h to 10 d PHI: (1) the total 14C-residue declined from 450 to 200 (1×) or 2900 to 1300 (5×) ppb, (2) the total 14C-residue was 78−92% extractable, (3) the extractable residue consisted of the parent as well as polar and avermectin-like residues, (4) the parent declined from 90 to 7 ppb (1×), and (5) polar residues in toto ranged from 120−170 ppb (1×). For the extractable residue, (1) 10 avermectin-like residues were identified with the parent accounting for 4−38% of the total, (2) the polar residues were found to be extremely complex, consisting of many minor components and no apparent conjugates, and (3) the polar residues in toto accounted for 23−75% of the total. Keywords: Emamectin; MK-0244; avermectin; metabolism; cabbage
Objective Measures of Emotion During Virtual Walks through Urban Environments (2011)

Previous studies were able to demonstrate different verbally stated affective responses to environments. In the present study we used objective measures of emotion. We examined startle reflex modulation as well as changes in heart rate and skin conductance while subjects virtually walked through six different areas of urban Paris using the StreetView tool of Google maps. Unknown to the subjects, these areas were selected based on their median real estate prices. First, we found that price highly correlated with subjective rating of pleasantness. In addition, relative startle amplitude differed significantly between the area with lowest versus highest median real estate price while no differences in heart rate and skin conductance were found across conditions. We conclude that interaction with environmental scenes does elicit emotional responses which can be objectively measured and quantified. Environments activate motivational and emotional brain circuits, which is in line with the notion of an evolutionary developed system of environmental preference. Results are discussed in the frame of environmental psychology and aesthetics.
Lacci, lacciuoli e cordoni della borsa (1990)

A partire da un'analisi dei costi per facoltà dell'Università di Modena nel decennio 1976/77 - 1985/86, il lavoro discute criticamente la nozione di autonomia dell'università prevista dalla legge n.168/1989.
Comparison of Community‐Associated and Health Care‐Associated Methicillin‐Resistant Staphylococcus aureus in Canada: Results from CANWARD 2007 (2009)

BACKGROUND: Community‐associated methicillin‐resistant Staphylococcus aureus (CA‐MRSA) differ from health care‐associated MRSA (HA‐MRSA) in their genotypic and phenotypic characteristics. The purpose of the present study was to compare the demographics, antimicrobial susceptibilities and molecular epidemiology of CA‐MRSA and HA‐MRSA in Canada. METHODS: In 2007, 385 MRSA isolates were collected from Canadian patients attending hospital clinics, emergency rooms, medical/ surgical wards and intensive care units. Susceptibilities to betalactams, clarithromycin, clindamycin, daptomycin, levofloxacin, linezolid, moxifloxacin, tigecycline, trimethoprim‐sulfamethoxazole and vancomycin were determined by Clinical and Laboratory Standards Institute broth microdilution. Strain typing was performed by pulsed‐field gel electrophoresis (PFGE) and the mec A, nuc and pvl genes were detected by polymerase chain reaction. RESULTS: Of the 385 MRSA, 19.5% were CA‐MRSA and 79.2% were HA‐MRSA as determined by PFGE. CA‐MRSA belonged to PFGE types CMRSA10/USA300 (66.7%) and CMRSA7/USA400 (33.3%); PFGE types identified among HA‐MRSA included CMRSA2/USA100/800 (81.6%), CMRSA6 (13.1%), CMRSA1/ USA600 (3.3%), CMRSA5/USA500 (1.3%), CMRSA3 (0.3%) and CMRSA9 (0.3%). Panton‐Valentine leukocidin (PVL) was detected in 94.7% of CA‐MRSA and 0.7% of HA‐MRSA. Resistance rates (CA‐MRSA versus HA‐MRSA) were 61.3% versus 97.7% to levofloxacin, 73.3% versus 96.7% to clarithromycin, 12.0% versus 74.8% to clindamycin and 0.0% versus 15.4% to trimethoprim‐sulfamethoxazole. No MRSA were resistant to vancomycin, linezolid, tigecycline or daptomycin. CONCLUSIONS: CA‐MRSA represented 19.5% of all MRSA. CA‐MRSA was significantly more susceptible to levofloxacin, clarithromycin, clindamycin and trimethoprim‐sulfamethoxazole than HA‐MRSA. Of CA‐MRSA, 94.7% were PVL‐positive while 99.3% of HA‐MRSA were PVL‐negative. CA‐MRSA is an emerging pathogen in Canadian hospitals.
The Antiproliferative Effect of Murine Interferon α/β on Early Bone Marrow-Derived Erythroid Precursors (BFU/e) (1985)

We have examined the antiproliferative effect of murine interferon (MuIFN) alpha/beta on a primitive class of erythroid precursors, the burst-forming units (BFUe) which give rise to macroscopic colonies of erythroblasts in plasma clots. Cultures were examined respectively on day 9 and on day 15; in both instances there was a significant reduction in the number of erythropoietic bursts in cultures exposed to IFN. The effect of IFN was more pronounced when the cells were cultured in the presence of suboptimal concentrations of erythropoietin and it could to a significant extent be reversed by ouabain at 10(-15) M. The latter finding is in line with observations made by others that growth factors can act as IFN antagonists. A comparison of BFUe derived from mice of two different genotypes, BALB/c and C57BL/6, revealed no difference in relative sensitivity to the antiproliferative effect of IFN. This is in contrast with the previously described fivefold greater sensitivity of the BALB/c genotype when a more differentiated class of erythroid precursors, the colony-forming units or CFUe, are exposed to IFN. Since the BFUe, studied in the present work, are a more primitive class of erythroid precursors than the CFUe, it can be concluded that the genes modulating the difference in sensitivity to IFN action on erythroid precursors are only expressed after a certain stage of differentiation has been reached.
A Study for Reliability Verification of Structural Design of Fast Steering Mirror with Voice Coil Actuators (2021)

Because laser weapons are relatively easy to use and can exert powerful energy with high efficiency versus cost, the laser weapons are being developed competitively in the defense industry. A fast steering mirror is the key component for precision tracking and automatic beam alignment, which are the main performances of laser weapons. The purpose of this study is to verify the structural design and driving reliability for implementing the target performance of a fast steering mirror using voice coil actuators. For the performance evaluation of a fast steering mirror, the driving range for the available thrust considering of the electromagnetic force and also the dynamic characteristics within the driving bandwidth were investigated through electromagnetic and structural analysis. In addition, the structural robustness was verified by securing a sufficient safety factor based on the analysis of the fatigue life for the area where the stress was concentrated.
Active face tracking and pose estimation in an interactive room (1996)

We demonstrate real-time face tracking and pose estimation in an unconstrained office environment with an active foveated camera. Using vision routines previously implemented for an interactive environment, we determine the spatial location of a user's head and guide an active camera to obtain foveated images of the face. Faces are analyzed using a set of eigenspaces indexed over both pose and world location. Closed loop feedback from the estimated facial location is used to guide the camera when a face is present in the foveated view. Our system can detect the head pose of an unconstrained user in real-time as he or she moves about an open room.
Tandem Sonogashira Coupling:  An Efficient Tool for the Synthesis of Diarylalkynes (2004)

[reaction: see text] The tandem Sonogashira coupling reaction of aryl halides provides an efficient method for the synthesis of diarylalkynes. Several aryl halides were coupled with 2-methyl-3-butyn-2-ol as acetylene source in the presence of PdCl2(PPh3)2 and CuI. Following the deprotection of the acetylene moiety in the same pot using a strong base, the Sonogashira coupling of a second aryl halide led to the formation of the appropriate diarylakyne. The established protocoll was successfully extended to the preparation of compound libraries.