gebhart/patrepeval huggingface dataset:
Neurophysiology of a Central Baroreceptor Pathway Projecting to Hypothalamic Vasopressin Neurons (1987)

Controversy exists as to the neural network whereby peripheral arterial baroreceptor information is transmitted to vasopressin (VP)-secreting neurons of the hypothalamic supraoptic nucleus (s.o.n.). In vivo electrophysiological studies in the rat were undertaken to characterize the selective depression of VP cell activity consequent to activation of peripheral baroreceptors. Electrical stimulation of the diagonal band of Broca (DB) in the rat evoked a similar selective inhibition of vasopressinergic neurons of the s.o.n. Local application of bicuculline, a GABA antagonist, abolished both the DB-evoked and baroreceptor-induced inhibition of VP-secreting neurons. In addition, recordings from DB neurons antidromically activated from the s.o.n. displayed an increase in firing consequent to baroreceptor activation, coinciding with the suppression of firing in s.o.n. VP neurons. These observations collectively indicate that an intrinsic GABA projection arising in the DB cell group selectively inhibits vasopressinergic neurons of the s.o.n. and that this pathway mediates peripheral arterial baroreceptor activity that influences the release of VP in the neurohypophysis. These data may be of critical importance in our understanding the etiology of those forms of experimental hypertension where abnormalities in central baroreceptor pathways have been implicated but not proven.
The Oracle Warehouse (1995)

Data warehouses are repositories that integrate and relational and non-relational data stores. Because summarize historical and reference data from numerous the warehouse integrates’ gateways and distributed sources. Warehoused data can be analyzed along several SQL processing, the warehoe cq load data from dimensions such as time, product, and geography to ari ‘opeiational system with an SQL imerf...seZecf identify trends and gain competitive advantage. statement.
Synthesis and some reactions of 3,3-dimethoxycylopropene (1972)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and some reactions of 3,3-dimethoxycylopropeneKeith B. Baucom and George B. ButlerCite this: J. Org. Chem. 1972, 37, 11, 1730–1732Publication Date (Print):June 1, 1972Publication History Published online1 May 2002Published inissue 1 June 1972https://pubs.acs.org/doi/10.1021/jo00976a012https://doi.org/10.1021/jo00976a012research-articleACS PublicationsRequest reuse permissionsArticle Views404Altmetric-Citations41LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Modeling missing data in knowledge space theory. (2015)

Missing data are a well known issue in statistical inference, because some responses may be missing, even when data are collected carefully. The problem that arises in these cases is how to deal with missing data. In this article, the missingness is analyzed in knowledge space theory, and in particular when the basic local independence model (BLIM) is applied to the data. Two extensions of the BLIM to missing data are proposed: The former, called ignorable missing BLIM (IMBLIM), assumes that missing data are missing completely at random; the latter, called missing BLIM (MissBLIM), introduces specific dependencies of the missing data on the knowledge states, thus assuming that the missing data are missing not at random. The IMBLIM and the MissBLIM modeled the missingness in a satisfactory way, in both a simulation study and an empirical application, depending on the process that generates the missingness: If the missing data-generating process is of type missing completely at random, then either IMBLIM or MissBLIM provide adequate fit to the data. However, if the pattern of missingness is functionally dependent upon unobservable features of the data (e.g., missing answers are more likely to be wrong), then only a correctly specified model of the missingness distribution provides an adequate fit to the data.
1-dimensional lanthanide halide crystals encapsulated within single-walled carbon nanotubes –a brief review (2005)

This brief review describes the crystallisation behaviour of selected lanthanide halides (LnX 3 , with Ln = La, Ce, Gd and X = Cl, I), confined to the nanometre-sized inner cavity of single-walled carbon nanotubes. The resulting LnX 3 @SWNT encapsulation composites were characterised using conventional high-resolution transmission electron microscopy techniques, combined with advanced digital image restoration approaches, enabling the complete structural determination of both the encapsulated crystal fragment and the surrounding nanotube. The studies reveal that some encapsulated 1-dimensional lanthanide halide crystal fragments maintain the overall structure of the respective bulk material, while others exhibit unprecedented crystal structure.
A novel culture device for the evaluation of three-dimensional extracellular matrix materials (2012)

Cell-matrix interactions in a three-dimensional (3D) extracellular matrix (ECM) are of fundamental importance in living tissue, and their in vitro reconstruction in bioartificial structures represents a core target of contemporary tissue engineering concepts. For a detailed analysis of cell-matrix interaction under highly controlled conditions, we developed a novel ECM evaluation culture device (EECD) that allows for a precisely defined surface-seeding of 3D ECM scaffolds, irrespective of their natural geometry. The effectiveness of EECD was evaluated in the context of heart valve tissue engineering. Detergent decellularized pulmonary cusps were mounted in EECD and seeded with endothelial cells (ECs) to study EC adhesion, morphology and function on a 3D ECM after 3, 24, 48 and 96 h. Standard EC monolayers served as controls. Exclusive top-surface-seeding of 3D ECM by viable ECs was demonstrated by laser scanning microscopy (LSM), resulting in a confluent re-endothelialization of the ECM after 96 h. Cell viability and protein expression, as demonstrated by MTS assay and western blot analysis (endothelial nitric oxide synthase, von Willebrand factor), were preserved at maintained levels over time. In conclusion, EECD proves as a highly effective system for a controlled repopulation and in vitro analysis of cell-ECM interactions in 3D ECM.
Thermophotovoltaic energy generation (2023)

Inventive systems and methods for the generation of energy using thermophotovoltaic cells are described. Also described are systems and methods for selectively emitting electromagnetic radiation from an emitter for use in thermophotovoltaic energy generation systems. In at least some of the inventive energy generation systems and methods, a voltage applied to the thermophotovoltaic cell (e.g., to enhance the power produced by the cell) can be adjusted to enhance system performance. Certain embodiments of the systems and methods described herein can be used to generate energy relatively efficiently.
On Developing System Dynamics Model for Business Process Simulation (2006)

Business operations can be formally described in business process models that capture activities, information, and flow embedded in business operation. System dynamics modeling is a set of conceptual tools that enable business process designers to build computer simulations of complex business process behaviors. System dynamics models provide accurate description of system behavior along the time dimension. It gives a convenient tool to conduct what if analysis though dynamics points of view. However, to develop system dynamics models requires keen understanding of the "physics" of the target business operations, business organizations, and financial structures and so on. This paper is aimed to provide heuristics and guidelines of developing system dynamics models based on given business process models along with associated reference contexts. An example, from supply chain management domain, of using business process models to derive system dynamics models is given in the paper.
Search for fractionally charged nuclear fragments in relativistic heavy ion collisions (1996)

We have investigated about 11 000 fragments with charge 6\ensuremath{\le}Z\ensuremath{\le}10 produced by 200 GeV/nucleon $^{32}\mathrm{S}$ projectiles and about 11 000 fragments with charge 6\ensuremath{\le}Z\ensuremath{\le}10 produced by 10.6 GeV/nucleon $^{197}\mathrm{Au}$ projectiles. Charges were measured using stacks of CR-39 plastic nuclear track detector foils. By multiple measurements on the surfaces of adjacent detector foils a charge resolution sufficient to identify fragment charges Z\ifmmode\pm\else\textpm\fi{}1/3 could be achieved over a minimum track length of a few mm. We found no evidence for a fast fragment with a charge differing from an integer by as much as 1/3. \textcopyright{} 1996 The American Physical Society.
Nonnormal CHF calculations (1987)

The purpose of this summary is to present the development of a statistically consistent procedure for creating a critical heat flux (CHF) correlation from raw experimental data and to demonstrate the application of the CHF correlation to the calculation of a minimum departure from nucleate boiling (DNB) ratio limit.
OVEREXPRESSION OF B7-H4 IN TUMOR INFILTRATED DENDRITIC CELLS (2011)

DCs infiltrated tumors appears to be phenotypically and functionally defective. B7-H4 was highlighted for its inhibitory role in T cell responses. In this study, we showed that B7-H4 was moderately expressed in imDCs, and up-regulated by IL-10, and TNF-α could counteract the up-regulatory effects of IL-10 on expression of B7-H4 in DCs in vitro. Furthermore, tumor infiltrated DCs expressed B7-H4 at high levels. Blockade of B7-H4 expressed in DCs highly resulted in enhanced T cell proliferation and IFN-γ production significantly. Otherwise, the high level of IL-10 and TNF-α was both detected in the tumor, which suggested that TNF-α can not antagonize the effects of IL-10 on expression of B7-H4 in DCs in vivo. These data indicate that tumor environment may condition local DCs to become dysfunctional in the phenotype, and that the high expression of B7-H4 may contribute to the tumor infiltrated DCs to mediate immune invasion.
A new generation of polyurethane vascular prostheses: Rara Avis or Ignis Fatuus? (1999)

Three polyurethane (PU) vascular grafts with novel designs were investigated and compared in terms of the microporous structure, reinforcement technology, polymer chemistry, microphase separation, and mechanical properties. The Corvita graft, composed of a poly(carbonate urethane) polymer, displayed a helically wound filament structure with communicating inter-fiber spaces. The reinforced model contained an external PET mesh impregnated with a protein sealant, and displayed good microphase separation, the highest Young's modulus in the longitudinal direction, and the second highest in the radial direction. The Thoratec graft was made of a polyetherurethaneurea with an average micropore size of 15 microns. Silicone was observed on both surfaces of the graft. The Thoratec device displayed a low degree of hydrogen-bonding among the urethane groups and had no well-organized hard-segment domains. Its mechanical strength was superior to that of the Pulse-Tec graft. A solid PU layer underneath the luminal surface precluded any communication between the luminal and adventitial sides. The Pulse-Tec prosthesis was composed of polyetherurethane, with an average micropore size of 28 microns. It offered the highest radial compliance, a high degree of hydrogen-bonding, a narrow molecular weight distribution, and a certain degree of microphase separation. Its tensile strength and hysteresis loss were inferior to those of the other two grafts.
Anti-alpha-galactosyl antibodies in chagasic patients. Possible biological significance. (1988)

1. Antibodies from Chagasic patients (Ch), bound to a column of immobilized purified glycoprotein 25-kDa antigen of Trypanosoma cruzi epimastigotes (gp25), were partially lytic (70% lysis at 50 micrograms/ml) to cultured metacyclic trypomastigotes (Y strain) in a complement-mediated reaction (alternative pathway). 2. Antibodies (Ch) eluted with galactose from a melibiose-Agarose column reacted in ELISA titration plates with gp25, whole cells of metacyclic trypomastigotes (Y strain), and less intensely with aqueous extracts of either T. cruzi (CL-14 strain) or Herpetomonas muscarum. 3. Agglutination of rabbit erythrocytes by anti-Gal antibodies from Chagasic patients or normal human sera (NHS) was inhibited by galactose and alpha-but not beta-anomeric galactosides. 4. Anti-Gal antibodies (Ch or NHS) were lytic to metacyclic trypomastigotes in complement-mediated reactions. 5. Agglutination of rabbit red cells by a serum sample from a T. cruzi-infected Rhesus monkey was inhibited by laminin. This serum was also lytic to metacyclic forms of T. cruzi (Y strain) involving the alternative complement pathway (70% lysis at 1:20 final dilution). 6. These results open the possibility of using anti-Gal antibodies for protection against infection by virulent T. cruzi.
Fabrication of Supercapacitors using Silver Nano Paste and Gel Electrolyte (2013)

폴리이미드(polyimide) 필름 위에 은(Ag) 나노 페이스트(paste)가 인쇄된 집전체 및 활성탄소(activated carbon)를 이용하여 제조한 페이스트와 5% potassium polyacrylate (PAAK) 겔(gel) 전해질을 이용하여 슈퍼캐패시터(supercapacitor) 반쪽전지(half cell)를 제작하였다. 집전체 및 전극은 스크린 인쇄를 이용하여 제작하였으며 인쇄된 집전체의 두께는 <TEX>$7.3{\mu}m$</TEX>이고 면저항은 <TEX>$5{\sim}7m{\Omega}/square$</TEX>이다. 전극 페이스트는 비표면적 <TEX>$1,968m^2/g$</TEX>인 활성탄소이고 도전재는 카본 블랙(carbon black)을 사용하였으며 바인더로는 poly (4-vinylphenol)를 7:1:3 비율로 혼합하고 2-(2-buthoxyethoxy) 에틸아세테이트(BCA)를 주 용매로 사용하여 제조하였다. 전기화학적 분석을 위해 순환-전압 전류법(cyclic voltammetry)을 이용하여 전기화학적 특성과 안정도를 평가하였으며 순환-전압전류법 측정을 위한 인가 전압의 범위는 -0.5 V~0.5 V이고 주사속도(scan rate)의 범위는 10~500 mV/s로 하였다. 제작된 슈퍼캐패시터 반쪽전지의 비축전 용량은 주사속도가 10 mV/s, 500 mV/s일 때 각각 44.04 F/g, 8.62 F/g이었다. The supercapacitors were fabricated using silver (Ag) nano paste and activated carbon paste on the polyimide (PI) film and 5% potassium polyacrylate (PAAK) was used for gel electrolyte. In this paper, the current collector film and the electrode film were fabricated using screen printing. The thickness of printed silver paste was <TEX>$7.3{\mu}m$</TEX> and the sheet resistance has the range of <TEX>$5-7m{\Omega}/square$</TEX>. An activated carbon with a surface area of <TEX>$1,968m^2/g$</TEX>, an electronic conducting agent (SUPER P, TIMCAL) and poly (4-vinylphenol) were mixed in 2-(2-buthoxyethoxy) ethyl acetate (BCA) with a ratio of 7:1:3 to fabricate the electrode paste. To analyze electrochemical characteristics, cyclic voltammetry was performed to evaluate the stability of the devices under the voltage range of -0.5-0.5 V. The calculated specific capacitances were 44.04 and 8.62 F/g for 10 and 500 mV/s scan rates, respectively.
Highly Active Multidentate Alkyne Metathesis Catalysts: Ligand‐Activity Relationship and Their Applications in Efficient Synthesis of Porphyrin‐Based Aryleneethynylene Polymers (2012)

Abstract A series of tris(arylmethyl)ammonium‐coordinated molybdenum(VI) propylidyne catalysts was synthesized. Such N‐ quarternized multidentate catalysts showed high robustness, strong resistance to small alkyne polymerization and significantly enhanced catalytic activity compared to their corresponding tris(arylmethyl)amine‐based analogues. The high activity of these new catalysts also enabled the efficient synthesis of ethynylene‐bridged porphyrin‐based arylene ethynylene polymers via alkyne metathesis, which represents a highly efficient, defect‐free, viable approach for the synthesis of this class of intriguing polymers.
Peeling of linearly elastic sheets using complex fluids at low Reynolds numbers (2022)

We investigate the transient, fluid structure interaction (FSI) of a non-Newtonian fluid peeling two linearly elastic sheets at low Reynolds numbers. Two different non-Newtonian fluids are considered; a simplified sPTT model, and an inelastic fluid with shear thinning viscosity (generalized Newtonian fluid). In the limit of small gap between the sheets, we invoke a lubrication approximation and numerically solve for the gap height between the two sheets during the start-up of a pressure-controlled flow. What we observe is that for an impulse pressure applied to the sheet inlet, the peeling front moves diffusively toward the end of the sheet when the fluid is Newtonian. However, when one examines a complex fluid with shear thinning, the propagation front moves sub-diffusively in time , but ultimately reaches the end faster due to an order of magnitude larger pre-factor for the propagation speed. We provide scaling analyses and similarity solutions to delineate several regimes of peeling based on the sheet elasticity, Wi number (for sPTT fluid), and shear thinning exponent (for generalized Newtonian fluid). To conclude, this study aims to afford to the experimentalist a system of knowledge to delineate the peeling characteristics of a certain class of complex fluids.
Biosynthesis of phenanthroindolizidine alkaloids: incorporation of 2-pyrrolidin-2-ylacetophenone and benzoylacetic acid and derivatives (1984)

2-Pyrrolidin-2-ylacetophenone (12) and its oxygenated derivatives, (13) and (14), bearing 14C and 3H labels are synthesized and are shown to be intact precursors for the Phenanthroindolizidine alkaloid, tylophorinine (16) in Tylophora asthmatica; the three amines, singly labelled with tritium, are shown to be precursors for tylophorine (3) and tylophorinidine (17). Benzoylacetic acid (9) and p-hydroxybenzoylacetic acid (10)but not 4-hydroxy-3-methoxybenzoylacetic acid, are also precursors for tylophorinine (16). The results allow partial description of the biosynthetic pathways to Phenanthroindolizidine alkaloids. A degradation is described which allowed the location of label in 2-pyrrolidin-2-ylacetophenone, derived from[5-14C]ornithine, to be established.
The use of the Foley balloon catheter in the tripod fracture (1971)

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Normative Aortic Valvar Measurements in Adults Using Cardiac Computed Tomography : A Potential Guide to Further Sophisticate Aortic Valve-Sparing Surgery (2022)

A thorough understanding of the anatomy of the aortic valve is necessary for aortic valve-sparing surgery. Normal valvar dimensions and their relationships in the living heart, however, have yet to be fully investigated in a 3-dimensional fashion.
Live cell imaging approaches reveal actin cytoskeleton-induced self-association of the actin-bundling protein WLIM1 (2013)

Crosslinking of actin filaments into bundles is essential for the assembly and stabilization of specific cytoskeletal structures. However, relatively little is known about the molecular mechanisms underlying actin bundle formation. The two LIM-domain-containing proteins define a novel and evolutionarily conserved family of actin-bundling proteins whose actin-binding and -crosslinking activities primarily rely on their LIM domains. Using TIRF microscopy, we describe real-time formation of actin bundles induced by tobacco NtWLIM1 in vitro. We show that NtWLIM1 binds to single filaments and subsequently promotes their interaction and zippering into tight bundles of mixed polarity. NtWLIM1-induced bundles grew by both elongation of internal filaments and addition of preformed fragments at their extremities. Importantly, these data are highly consistent with the modes of bundle formation and growth observed in transgenic Arabidopsis plants expressing a GFP-fused Arabidopsis AtWLIM1 protein. Using two complementary live cell imaging approaches, a close relationship between NtWLIM1 subcellular localization and self-association was established. Indeed, both BiFC and FLIM-FRET data revealed that, although unstable NtWLIM1 complexes can sporadically form in the cytosol, stable complexes concentrate along the actin cytoskeleton. Remarkably, disruption of the actin cytoskeleton significantly impaired self-association of NtWLIM1. In addition, biochemical analyses support the idea that F-actin facilitates the switch of purified recombinant NtWLIM1 from a monomeric to a di- or oligomeric state. On the basis of our data, we propose a model in which actin binding promotes the formation and stabilization of NtWLIM1 complexes, which in turn might drive the crosslinking of actin filaments.
A Denial-of-Service Resistant Quality-of-Service Signaling Protocol for Mobile Ad Hoc Networks (2005)

Quality-of-service (QoS) signaling protocols for mobile ad hoc networks (MANETs) are highly vulnerable to attacks. In particular, a class of denial-of-service (DoS) attacks can severely cripple network performance with relatively little effort expended by the attacker. We propose a distributed QoS signaling protocol that is resistant to a large class of DoS attacks. The key elements of the scheme are: sensing of available bandwidth, traffic policing, and rate monitoring. The proposed signaling scheme provides QoS for real-time traffic and achieves a compromise between signaling protocols that require the maintenance of per-flow state and those that are completely stateless. The signaling scheme scales gracefully in terms of the number of nodes and/or traffic flows in the MANET. We analyze the key security properties of the protocol and present simulation results to demonstrate its resistance to DoS attacks
Fluorine-18-Labeled Antagonist for PET Imaging of Kappa Opioid Receptors (2016)

Kappa opioid receptor (KOR) antagonists are potential drug candidates for diseases such as treatment-refractory depression, anxiety, and addictive disorders. PET imaging radiotracers for KOR can be used in occupancy study to facilitate drug development, and to investigate the roles of KOR in health and diseases. We have previously developed two <sup>11</sup>C-labeled antagonist radiotracers with high affinity and selectivity toward KOR. What is limiting their wide applications is the short half-life of <sup>11</sup>C. Herein, we report the synthesis of a first <sup>18</sup>F-labeled KOR antagonist radiotracer and the initial PET imaging study in a nonhuman primate.
Directional Crystallizing Si Films with a Fundamental Continuous Wave Yttrium Aluminum Garnet Laser (Zone Melting for Film) (2005)

To form large-grained polycrystalline-silicon (poly-Si) films on glass substrates, we propose a new lateral crystallization method, zone melting for film, which uses a high-power fundamental continuous wave yttrium aluminum garnet (CW-YAG) laser and an absorption layer. The laser's infrared light is changed into thermal energy at the absorption layer and heats the amorphous Si (a-Si) film. Next, the Si film is zone-melted and solidified in one direction with a scanning laser beam. By this method, columnar structured Si films were successfully formed with scanning velocities from 400 to 1000 mm/s. Very large typical grains of 1 or 2 µm by few hundreds of µm were obtained on both glass and quartz substrates, and the long axes of the grains were almost parallel to the laser scanning direction. Textures were also observed in these columnar structured Si films. Recombination carrier lifetimes of these films were several times longer than those of conventional low-temperature-processed poly-Si films.