gebhart/patrepeval huggingface dataset:
Comparing Deep Learning strategies for paired but unregistered multimodal segmentation of the liver in T1 and T2-weighted MRI (2021)

We address the problem of multimodal liver segmentation in paired but unregistered T1 and T2-weighted MR images. We compare several strategies described in the literature, with or without multi-task training, with or without pre-registration. We also compare different loss functions (cross-entropy, Dice loss, and three adversarial losses). All methods achieved comparable performances with the exception of a multi-task setting that performs both segmentations at once, which performed poorly.
The Ethaline Effect on Feruloyl Esterase Activity (2019)

In recent years, extractions using natural deep eutectic. [...]
Polynuclear Complexes of the Pendent-Arm Ligand 1,4,7-Tris(acetophenoneoxime)-1,4,7-triazacyclononane (2002)

The ligand 1,4,7-tris(acetophenoneoxime)-1,4,7-triazacyclononane (H(3)L) has been synthesized and its coordination properties toward Cu(II), Ni(II), Co(II), and Mn(II) in the presence of air have been investigated. Copper(II) yields a mononuclear complex, [Cu(H(2)L)](ClO(4)) (1), cobalt(II) and manganese(II) ions yield mixed-valence Co(III)(2)Co(II) (2a) and Mn(II)(2)Mn(III) (4) complexes, whereas nickel(II) produces a tetranuclear [Ni(4)(HL)(3)](2+) (3) complex. The complexes have been structurally, magnetochemically, and spectroscopically characterized. Complex 3, a planar trigonal-shaped tetranuclear Ni(II) species, exhibits irregular spin-ladder. Variable-temperature (2-290 K) magnetic susceptibility analysis of 3 demonstrates antiferromagnetic exchange interactions (J = -13.4 cm(-1)) between the neighboring Ni(II) ions, which lead to the ground-state S(t) = 2.0 owing to the topology of the spin-carriers in 3. A bulk ferromaganetic interaction (J = +2 cm(-1)) is prevailing between the neighboring high-spin Mn(II) and high-spin Mn(III) ions leading to a ground state of S(t) = 7.0 for 4. The large ground-state spin value of S(t) = 7.0 has been confirmed by magnetization measurements at applied magnetic fields of 1, 4 and 7 T. A bridging monomethyl carbonato ligand formation occurs through an efficient CO(2) uptake from air in methanolic solutions containing a base in the case of complex 4.
[A comparative study of the effect of Zoladex treatment versus orchiectomy in patients with advanced prostatic cancer]. (1996)

The study entered sixty patients with advanced carcinoma of the prostate that were treated and followed-up by the authors. The median age was 70.3 years (range 58-83 years). In all patients a prostatic carcinoma has been morphologically proven. Orchiectomy was performed in 27 of them. Conservative treatment with Zoladex-monotherapy was applied in 21 patients and a combination of orchiectomy plus Zoladex-in 12 of the remaining. All patients were followed-up for the period of 3 months. Subjective and objective parameters were evaluated at 2, 4, 8 and 12 weeks during the treatment. Positive response to treatment was reported in 76% of the patients from the group of orchiectomy alone, 72% among the patients in the group of Zoladex depot and up to 80% in patients treated with orchiectomy plus Zoladex. The average time to achieve positive response was stated to be seven weeks for orchiectomy and Zoladex as a monotherapy and six weeks for the combination therapy.
Age Invaders: Inter-generational Mixed Reality Family Game (2006)

This paper introduces Age Invaders (AI), a novel interactive inter-generation social-physical game which allows the elderly to play harmoniously together with children in physical space while parents can participate in the game play in real time remotely through the internet
Olive Leaf extract: Olea europaea (2005)

A current buzzword among CM users is seen as a cure-all for anything from the common cold to arthritis, asthma and eczema. Lesley Braun attempts to discern efficacy behind the popularity.
Cytokines Maintain Lymphocyte Homeostasis through the Activity of Cdc25A (B56) (2007)

Abstract Homeostasis of the peripheral immune system is maintained through signals transduced by cytokines like interleukin-7 (IL-7). In the absence of IL-7 cells undergo apoptosis, while excess IL-7 leads to proliferation. The mechanisms by which IL-7 regulates these processes are poorly understood. We observed that expressing an anti-apoptotic protein (BCL-2) or inhibiting a pro-apoptotic protein (BAX) prevented cell death but did not support growth. Using cytokine-dependent lymphocytes, we found that the G1-to-S phase progression was not solely dependent on the synthesis of cyclin dependent kinases (cdks) and cyclins or the inactivation of inhibitors. Rather it was the removal of inhibitory phosphorylations on cdks by a phosphatase, Cdc25A, which primarily transduced cytokine-mediated growth signals. Cytokine deprivation lead to cell cycle arrest by inducing the activity of p38 MAPK, which destabilized Cdc25A. Inhibiting p38 or expressing a mutant Cdc25A, in which p38 target sites were mutated, promoted cell cycling independent of a cytokine signal. Cells expressing the Cdc25A mutant, in the absence of cytokines, actively synthesized DNA, expressed hyperphosphorylated Rb protein, maintained glucose uptake and did not undergo apoptosis, even in the presence of p27. Cdc25A is a novel transducer of cytokine-mediated growth signals and regulation of its activity is a means by which IL-7 controls proliferation.
Electrocrystallization of phase I, CuTCNQ (TCNQ= 7, 7, 8, 8-tetracyanoquinodimethane), on indium tin oxide and boron-doped diamond electrodes (2006)

The electrochemical reduction of TCNQ to TCNQ•- in acetonitrile in the presence of [Cu(MeCN)4]+ has been undertaken at boron-doped diamond (BDD) and indium tin oxide (ITO) electrodes. The nucleation and growth process at BDD is similar to that reported previously at metal electrodes. At an ITO electrode, the electrocrystallization of more strongly adhered, larger, branched, needle-shaped phase I CuTCNQ crystals is detected under potential step conditions and also when the potential is cycled over the potential range of 0.7 to −0.1 V versus Ag/AgCl (3 M KCl). Video imaging can be used at optically transparent ITO electrodes to monitor the growth stage of the very large branched crystals formed during the course of electrochemical experiments. Both in situ video imaging and ex situ X-ray diffraction and scanning electron microscopy (SEM) data are consistent with the nucleation of CuTCNQ taking place at a discrete number of preferred sites on the ITO surface. At BDD electrodes, ex situ optical images show that the preferential growth of CuTCNQ occurs at the more highly conducting boron-rich areas of the electrode, within which there are preferred sites for CuTCNQ formation.
Unidirectionality of semiconductor ring lasers: theory and experiment (2003)

Integrated semiconductor ring lasers are designed to achieve unidirectional operation with S-crossover waveguides or retro-reflectors. Greater than 20dB unidirectionality is demonstrated both theoretically and experimentally.
Monocular Total Capture: Posing Face, Body, and Hands in the Wild (2018)

We present the first method to capture the 3D total motion of a target person from a monocular view input. Given an image or a monocular video, our method reconstructs the motion from body, face, and fingers represented by a 3D deformable mesh model. We use an efficient representation called 3D Part Orientation Fields (POFs), to encode the 3D orientations of all body parts in the common 2D image space. POFs are predicted by a Fully Convolutional Network (FCN), along with the joint confidence maps. To train our network, we collect a new 3D human motion dataset capturing diverse total body motion of 40 subjects in a multiview system. We leverage a 3D deformable human model to reconstruct total body pose from the CNN outputs by exploiting the pose and shape prior in the model. We also present a texture-based tracking method to obtain temporally coherent motion capture output. We perform thorough quantitative evaluations including comparison with the existing body-specific and hand-specific methods, and performance analysis on camera viewpoint and human pose changes. Finally, we demonstrate the results of our total body motion capture on various challenging in-the-wild videos. Our code and newly collected human motion dataset will be publicly shared.
New efficacy of LTRAs (montelukast sodium): it possibly prevents food-induced abdominal symptoms during oral immunotherapy (2014)

The findings from this retrospective study suggest that the administration of LTRAs is useful for the prevention of adverse allergic reactions such as abdominal pain during OIT.
Poder de mercado das exportações brasileiras de carne bovina in natura para a União Europeia no período 1995-2008 (2009)

The European Union is the main market of the exporting sector of beef from Brazil, which is characterized by protectionist practices that distort the market equilibrium. Moreover, the Brazilian exports of fresh beef to the EU have suffered continuous declines. From this context, the main objective of this paper is to measure the market power of Brazil’s exports of fresh beef to the EU in the period from 1995 to 2008. The study uses the New Empirical Industrial Organization (NEIO) approach based on a system of supply and demand. The estimated value obtained for the parameter of market power was 0.8205, which is much closer to the Cournot-Nash solution (oligopoly). This result is consistent with information form trade in the European market, given the low number of competing countries, a fact which shows evidence of strong barriers to enter/exit from this sector.Key words: beef, European Union, NEIO, market power.
Metabolic engineering of Corynebacterium glutamicum for the production of cis, cis-muconic acid from lignin (2018)

Our findings open the door to valorize lignin, the second most abundant polymer on earth, by metabolically engineered C. glutamicum for industrial production of MA and potentially other chemicals.
Direct access colonoscopy service for bowel cancer screening produces a positive financial benefit for patients and local health districts (2018)

The introduction of DACS in the public system in Australia is of financial benefit to patients and to the local health service provider. It is likely to produce health benefits to non-screening patients, by means of freeing consultations to be used for other indications.
Diagnosi di nuovi Artropodi trovati in Sardegna (1) (1883)

(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Single gold atoms stabilized on nanoscale metal oxide supports are catalytic active centers for various reactions (2015)

Key recent findings that demonstrate that single‐gold atom sites stabilized on various oxide supports by –O bonds are the unique catalytic sites for a number of reactions, including the water‐gas shift reaction, methanol partial oxidation and steam reforming reactions, and the selective dehydrogenation of ethanol are summarized herein. Atomic dispersion of gold on various metal oxides was followed with aberration‐corrected high angle annular dark field/scanning transmission microscopy imaging and x‐ray absorption spectroscopy (XANES/EXAFS). Gold nanoparticles and subnanometer clusters are active only through their interfacial atoms directly interacting with the support, hence if present, they entail precious metal waste. From a design perspective, the important feature in these supported catalysts is the creation of many single‐site gold species anchored on the oxide support to maximize activity. Atomic gold‐centered catalyst designs afford 100% atom efficiency, and more importantly, have distinct product selectivity, different from that of extended metal surfaces. Novel experimental synthesis methods of atomically dispersed Au catalysts are discussed, which pave the way for the efficient use of precious metals, broadening the application of properly designed gold and other precious metals (Pt, Pd) to different reactions in energy conversion and green chemicals production. © 2015 American Institute of Chemical Engineers AIChE J , 62: 429–439, 2016
Tobramycin in Bone Cement (1983)

In this prospective clinical study, ten patients were treated by revision of total hip arthroplasties utilizing tobramycin-impregnated bone cement. After the operation, serum, urine, and wound suction drainage concentrations of tobramycin were determined serially by radioimmunoassay. Although high local wound concentrations, 5.7 micrograms/ml, were maintained for as long as 48 hours, serum concentration never reached even normal therapeutic ranges (greater than 2.0 micrograms/ml). There were no immediate postoperative infections; all patients are pain-free and ambulate without external support two years after surgery. One patient who had had a preoperative infection was successfully treated for late manifestation of infection 24 months after revision. Based on the evidence obtained in this study, tobramycin in bone cement is currently acceptable for clinical use.
Nuclear proteomic changes linked to soybean rust resistance (2010)

Soybean rust, caused by the fungus Phakopsora pachyrhizi, is an emerging threat to the US soybean crop. In an effort to identify proteins that contribute to disease resistance in soybean we compared a susceptible Williams 82 cultivar to a resistant Williams 82 inbred isoline harboring the Rpp1 resistance gene (R-gene). Approximately 4975 proteins from nuclear preparations of leaves were detected using a high-throughput liquid chromatography-mass spectrometry method. Many of these proteins have predicted nuclear localization signals, have homology to transcription factors and other nuclear regulatory proteins, and are phosphorylated. Statistics of summed spectral counts revealed sets of proteins with differential accumulation changes between susceptible and resistant plants. These protein accumulation changes were compared to previously reported gene expression changes and very little overlap was found. Thus, it appears that numerous proteins are post-translationally affected in the nucleus after infection. To our knowledge, this is the first indication of large-scale proteomic change in a plant nucleus after infection. Furthermore, the data reveal distinct proteins under control of Rpp1 and show that this disease resistance gene regulates nuclear protein accumulation. These regulated proteins likely influence broader defense responses, and these data may facilitate the development of plants with improved resistance.
Naive-Deep Face Recognition: Touching the Limit of LFW Benchmark or Not? (2015)

Face recognition performance improves rapidly with the recent deep learning technique developing and underlying large training dataset accumulating. In this paper, we report our observations on how big data impacts the recognition performance. According to these observations, we build our Megvii Face Recognition System, which achieves 99.50% accuracy on the LFW benchmark, outperforming the previous state-of-the-art. Furthermore, we report the performance in a real-world security certification scenario. There still exists a clear gap between machine recognition and human performance. We summarize our experiments and present three challenges lying ahead in recent face recognition. And we indicate several possible solutions towards these challenges. We hope our work will stimulate the community's discussion of the difference between research benchmark and real-world applications.
Palmitoylation of p59fyn is reversible and sufficient for plasma membrane association. (1997)

Members of the Src family of protein tyrosine kinases are localized to subspecialized regions of the plasma membrane. Herein we show that the N-terminal SH4 region of the Src family member p59fyn (Fyn) is both necessary and sufficient for targeting of Fyn and heterologous proteins to the plasma membrane and detergent-insoluble subdomains. Attachment of the first 16 amino acids of Fyn to a normally cytosolic protein, beta-galactosidase, resulted in distinct plasma membrane localization of the chimeric protein. Mutation of the palmitoylation site (cysteine-3) within Fyn16-beta-galactosidase or wild-type Fyn abrogated plasma membrane localization, resulting in redistribution of the mutant proteins into intracellular membranes. Substitution of the SH4 motif within Fyn with heterologous sequences from other palmitoylated proteins (G alpha o and GAP43) revealed that the presence of palmitate is sufficient to direct plasma membrane localization independent of surrounding amino acid sequences and myristate. Palmitoylated Fyn chimeras were also enriched in the Triton X-100-resistant matrix, whereas nonpalmitoylated forms of these proteins were detected in the detergent-soluble fraction. The palmitate moiety on Fyn exhibited a half-life of 1.5-2 h. In contrast, the half-life of the polypeptide backbone was 8 h, indicating that palmitoylation is a reversible modification. These studies establish that the palmitoylated SH4 sequence of Fyn can be used to specifically target proteins to the plasma membrane in a reversible manner.
Conformational and configurational studies on N-(substituted phenyl)pyranosylamine derivatives by high-resolution nuclear magnetic resonance spectroscopy (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTConformational and configurational studies on N-(substituted phenyl)pyranosylamine derivatives by high-resolution nuclear magnetic resonance spectroscopyLin Wang, Tai Shun Lin, and Alan C. SartorelliCite this: J. Org. Chem. 1983, 48, 17, 2891–2897Publication Date (Print):August 1, 1983Publication History Published online1 May 2002Published inissue 1 August 1983https://pubs.acs.org/doi/10.1021/jo00165a020https://doi.org/10.1021/jo00165a020research-articleACS PublicationsRequest reuse permissionsArticle Views65Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Identifying compartment-specific non-HLA targets after renal transplantation by integrating transcriptome and “antibodyome” measures (2009)

We have conducted an integrative genomics analysis of serological responses to non-HLA targets after renal transplantation, with the aim of identifying the tissue specificity and types of immunogenic non-HLA antigenic targets after transplantation. Posttransplant antibody responses were measured by paired comparative analysis of pretransplant and posttransplant serum samples from 18 pediatric renal transplant recipients, measured against 5,056 unique protein targets on the ProtoArray platform. The specificity of antibody responses were measured against gene expression levels specific to the kidney, and 2 other randomly selected organs (heart and pancreas), by integrated genomics, employing the mapping of transcription and ProtoArray platform measures, using AILUN. The likelihood of posttransplant non-HLA targets being recognized preferentially in any of 7 microdissected kidney compartments was also examined. In addition to HLA targets, non-HLA immune responses, including anti-MICA antibodies, were detected against kidney compartment-specific antigens, with highest posttransplant recognition for renal pelvis and cortex specific antigens. The compartment specificity of selected antibodies was confirmed by IHC. In conclusion, this study provides an immunogenic and anatomic roadmap of the most likely non-HLA antigens that can generate serological responses after renal transplantation. Correlation of the most significant non-HLA antibody responses with transplant health and dysfunction are currently underway.
A performance evaluation of the software-implemented fault-tolerancecomputer (1986)

The results of a performance evaluation of the Software-Implemented Fault-Tolerance (SIFT) computer system conducted in the NASA Avionics Integration Research Laboratory are presented. The essential system functions are described and compared to both earlier design proposals and subsequent design improvements. Using SIFT's specimen task load, the executive tasks, such as reconfiguration, clock synchronization, and interactive consistency, are found to consume significant computing resources. Together with other system overhead (e.g., voting and scheduling), the operating system overhead is in excess of 60%. The authors propose specific design changes that reduce this overhead burden significantly.
Cell-type-specific transactivation of the parathyroid hormone-related protein gene promoter by the human T-cell leukemia virus type I (HTLV- I) tax and HTLV-II tax proteins (1993)

The human T-cell leukemia virus type I (HTLV-I) and HTLV-II Tax proteins are potent transactivators of viral and cellular gene expression. Using deletion mutants, the downstream parathyroid hormone- related protein (PTHrP) promoter is shown to be responsive to both HTLV- I and HTLV-II Tax as well as the AP1/c-jun proto-oncogene. Transactivation of PTHrP by Tax was seen in T cells but not in B-cell lines or fibroblasts. A carboxy terminal Tax deletion mutant was deficient in transactivation of both the PTHrP and IL2R alpha promoters but not the HTLV-I long terminal repeat (LTR). Exogenous provision of NFkB rescued IL2R alpha expression but not the PTHrP promoter. Thus, HTLV-I Tax, HTLV-II Tax, and c-jun transactivate PTHrP and may contribute to the pathogenesis of hypercalcemia in adult T-cell leukemia.
Generic Patch Inference (2008)

A key issue in maintaining Linux device drivers is the need to update drivers in response to evolutions in Linux internal libraries. Currently, there is little tool support for performing and documenting such changes. In this paper we present a tool, spdiff, that identifies common changes made in a set of pairs of files and their updated versions, and extracts a generic patch performing those changes. Library developers can use our tool to extract a generic patch based on the result of manually updating a few typical driver files, and then apply this generic patch to other drivers. Driver developers can use it to extract an abstract representation of the set of changes that others have made. Our experiments on recent changes in Linux show that the inferred generic patches are more concise than the corresponding patches found in commits to the Linux source tree while being safe with respect to the changes performed in the provided pairs of driver files.