gebhart/patrepeval huggingface dataset:
Iowa Greenhouse Applicators' Preceptions and Use of Personal Protective Equipment (1994)

A mail survey of Iowa greenhouse pesticide applicators was conducted in 1992 to establish benchmark data concerning use of personal protective equipment (PPE), safety attitudes, and experience with pesticide-related illness symptoms before the implementation of the Worker Protection Standard for Agricultural Pesticides. A 72% response rate provided 185 observations revealing that 79% were employees of firms, but the remaining 21% were self-employed. Hypotheses of difference in use of P PE between the self-employed and employees of firms were not confirmed except with relation to use of regular work gloves, disposable coveralls, and boots. Applicators' clothing was reported to meet pesticide label requirements. Few applicators reported acute or chronic health effects associated with pesticide use, and no differences we refound between the employees and the self-employed. Most (72%) employees decided when to replace their uniforms. This' study demonstrated that greenhouse applicators want further information about PPE and need education about its laundering and storage.
Nitrile hydratase from a thermophilic Bacillus smithii (1998)

A novel thermophilic Bacillus smithii strain SC-J05-1, isolated from a hot spring, had the ability of hydrating nitrile to form amide. The nitrile hydratase was purified to homogeneity from the microbial cells of SC-J05-1 and was characterized. The enzyme was a 130-kDa protein composed of two different subunits (25.3 kDa and 26.8 kDa) and contained cobalt ions. This enzyme had the optimal temperature of 40°C and was stable up to 50°C. The optimal pH was in the alkaline region higher than pH 10.
Mechanism of neuroprotection by donepezil pretreatment in rat cortical neurons chronically treated with donepezil (2008)

Previously, we showed that in rat cortical neurons, chronic donepezil treatment (10 microM, 4 days) up-regulates nicotinic receptors (nAChR) and makes neurons more sensitive to the neuroprotective effect of donepezil. Here we examined the mechanism of donepezil-induced neuroprotection in neurons chronically treated with donepezil. The mechanism of neuroprotection was examined under different conditions of exposure to glutamate, acute and moderate, that induce cell death associated with necrotic and apoptotic cell death, respectively. Concomitant treatment with antagonists of nAChRs but not muscarinic receptors inhibited donepezil pretreatment-induced neuroprotection against acute glutamate treatment-induced death. Donepezil pretreatment prevented acute glutamate- and ionomycin-induced neurotoxicity, but not S-nitrosocysteine-induced neurotoxicity, suggesting that donepezil protects neurons via nAChR at levels before nitric oxide synthase activation against acute glutamate neurotoxicity. Concomitant treatment with antagonists of nAChR or phosphatidylinositol 3-kinase (PI3K) signaling inhibitors significantly inhibited neuroprotection against moderate glutamate neurotoxicity and decreased the phosphorylation level of Akt. Neuroprotection was also inhibited by treatment with inhibitor of mitogen-activated protein kinase (MAPK) kinase. These results suggest that donepezil protects neurons against moderate glutamate neurotoxicity via nAChR-PI3K-Akt and MAPK signaling pathways. This study provides novel insight into the mechanism of donepezil-induced neuroprotection that involves nAChR up-regulation.
Recombinant music: using the computer to explore musical style (1991)

A research project called Experiments in Musical Intelligence (EMI) is discussed. One subprogram of EMI is an expert system that uses pattern recognition processes to create recombinant music, i.e. music written in the styles of various composers by means of a contextual recombination of elements in the music of those composers. This EMI subprogram separates and analyzes musical pitches and durations and then mixes and recombines the patterns of these pitches and durations so that while each new composition is different, it substantially conforms to the style of the original. The fundamental problems in building a program to produce effective recombinant music are identified. The three steps used by the EMI program are discussed. They are: pattern matching for characteristics of the composer's style, analyzing each component for its deep hierarchical musical function, and reassembling the parts sensitively with a technique drawn from natural-language processing. Some examples of EMI's output are examined.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Bit-Interleaved Multiple Access: Improved Fairness, Reliability, and Latency for Massive IoT Networks (2023)

Internet of Things (IoT) networks require massive connections in dense areas. Therefore, a resource-efficient multiple access scheme seems inevitable to enable immense connectivity where multiple devices have to share the same resource block (RB). Nonorthogonal multiple access (NOMA) has been considered as the strongest candidate in recent years. However, in this article, by considering the practical implementation, we first provide a true power allocation (PA) constraint with finite alphabet inputs for conventional downlink NOMA and demonstrate that it cannot support massive connections in practical systems. To this end, we propose the bit-interleaved multiple access (BIMA) scheme in downlink IoT networks. The proposed BIMA scheme implements bitwise multiaccess interleaving and deinterleaving at the transceiver ends and there are no strict PA constraints, unlike conventional NOMA, thus allowing a high number of devices in the same RB. We provide a comprehensive analytical framework for BIMA by investigating all key performance indicators (KPIs) to present both information-theoretic [i.e., ergodic capacity (EC) and outage probability (OP)] and finite alphabet inputs [i.e., bit error rate (BER)] performance metrics with both instantaneous and statistical channel ordering. In addition, we define Jain’s fairness index and proportional fairness index (PFI) in terms of all KPIs. Based on the extensive computer simulations, we reveal that BIMA outperforms conventional NOMA significantly, with a performance gain of up to 20–30 dB in terms of KPIs in some scenarios. In other words, compared to conventional NOMA schemes, the same KPIs are met in BIMA with 20–30 dB less transmit power, which is quite promising for energy-limited use cases. Moreover, this performance gain becomes greater when more IoT devices are supported. BIMA provides a full diversity order for all IoT devices and enables the implementation of an arbitrary number of devices and modulation orders, which is crucial for IoT networks where a huge number of devices should be supported in a single RB in dense areas. In addition to the overall performance gain, BIMA guarantees a fairness system where none of the devices gets a severely degraded performance and the sum-rate is shared in a fair manner among devices. It guarantees QoS satisfaction for all devices. Finally, we provide an intense complexity and latency analysis for BIMA and demonstrate that it provides lower latency compared to conventional NOMA receivers, since it allows parallel computation at the receivers and no iterative operations are required. We show that compared to conventional NOMA receivers, BIMA reduces latency by up to 350% for specific IoT devices and 170% on average.
An innovative, safe and sterile sigmoid access (ISSA) for NOTES (2007)

The transcolonic approach using an innovative guide tube is feasible and safe. The technique described offers mentionable advantages and therefore reduces the known shortcomings of NOTES. However, further studies are needed to approve our results of an initial evaluation.
ChemInform Abstract: Supramolecular Transport of Metal Ammine and Amine Complexes Through Chloroform Membranes by the Natural Ionophore Lasalocid A. The Selective Enantiomeric Transport of Chiral Metal Complexes (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Hepatocyte Transplantation in Man (1993)

Recent advances in liver transplantation have caused a serious shortage of donor livers, and a consensus on determining brain death has not been reached by the medical community in several countries, including Japan. To overcome these circumstances, hepatocellular transplantation (HCTX) has been attempted because HCTX requires no vascular anastomosis and donor hepatocytes are easy to obtain from living donors, and easy to preserve for a long time. In many experimental studies on HCTX some promising findings have been obtained, but clinically there has been little progress. Our success with survival of autotransplanted monkey hepatocytes and the development of a preparation of human hepatocytes has renewed interest in clinical HCTX. A multipuncture perfusion method or collagenase perfusion via the umbilical vein enables us to obtain approximately 1 × 108 hepatocytes from partially resected liver (60 g). The clinical trial of HCTX into the spleen was performed in 10 patients in Japan. A CT image, taken 1 mo after HCTX, showed a low density area corresponding to the inoculated site, which suggested that the transplanted hepatocytes survived and possessed hepatocellular function. One patient who sustained hepatic encephalopathy and massive ascites has now returned to work 11 mo after HCTX and hepatic artery ligation. However, there were no definite findings for functional support of damaged livers by HCTX in the spleen. We will review our experiments on HCTX, and describe the current and future aspects of HCTX.
ChemInform Abstract: NEUE SYNTHESE VON PYRAZOLO(4,3‐C)PYRIDINEN ALS STRUKTUR‐ANALOGA VON PURINBASEN‐ANTAGONISTEN (1971)

Abstract Pyrazolylaldehyde, wie z.B. (I),werden nach Knoevenagel und Doebner mit Malonsäure (II) zu den Derivaten (III) (78 bzw. 75% Ausbeute) kondensiert, die über die entsprechenden Azide bei 75°C in die Isocyanate (IV) übergeführt werden.
Artrorisi astragalo-calcaneare: endortesi riassorbibile (2010)

Artrorisi astragalo-calcaneare, endortesi riassorbibile, per il trattamento del piede piatto del bambino
Honeypot forensics for system and network SIEM design (2013)

International audience
Hepatic micrometastases in the rat: ferrite-enhanced MR imaging. (1988)

A rat tumor model was used to evaluate the ability of ferrite-enhanced magnetic resonance (MR) imaging to demonstrate hepatic metastases smaller than 1 cm. Twenty-eight rat livers were inoculated with 5 X 10(5) mammary carcinoma cells and imaged with a 0.6-T MR system. Non-enhanced and ferrite-enhanced images were analyzed and correlated with autopsy findings for each rat. Lesion detection rates correlated closely with cancer-to-liver contrast-to-noise ratios. Ferrite-enhanced MR imaging demonstrated significantly more lesions than non-enhanced imaging (P less than .05) and decreased the threshold size for lesion detectability (less than 2 mm). Ferrite also enabled more accurate measurements of the lesions (r = .96).
GB: A New Grid-Based Binding Approach for High-Level Synthesis (2005)

This paper describes a new approach to connectivity binding for high-level synthesis, The new approach is based on deriving geometric communication information from a state graph. The derived information is used to produce bindings that lead to efficient communication structures in the final layouts. It is important because routing may account for a significant portion of the layout area and long communication lines tend to lead to longer machine state cycle times. It becomes even more critical us feature sizes are reduced. The heuristics in this paper use a new grid-based binding approach that produces quulity results on the commonly run benchmarks in only a few tenths of a second of CPU time on a Sun 41490. The work presented in [his paper also has an impact on research in partitioning and in bringing useful information from higher levels of abstraction down to final layout.
Finding the order in complexity: The electronic structure of 14-1-11 zintl compounds (2021)

Yb14MnSb11 and Yb14MgSb11 have rapidly risen to prominence as high-performing p-type thermoelectric materials. However, the fairly complex crystal structure of A14MX11 Zintl compounds renders the interpretation of the electronic band structure obscure, making it difficult to chemically guide band engineering and optimization efforts. In this work, we delineate the valence-balanced Zintl chemistry of A14MX11 compounds using the molecular orbital theory. By analyzing the electronic band structures of Yb14MgSb11 and Yb14AlSb11, we show that the conduction band minimum is composed of either an antibonding molecular orbital originating from the (Sb3)7– trimer or a mix of atomic orbitals of A, M, and X. The singly degenerate valence band is comprised of non-bonding Sb pz orbitals primarily from the Sb atoms in the (MSb4)m– tetrahedra and of isolated Sb atoms distributed throughout the unit cell. Such a chemical understanding of the electronic structure enables strategies to engineer electronic properties (e.g., the bandgap) of A14MX11 compounds.
Risk of metastatic disease using [18F]PSMA-1007 PET/CT for primary prostate cancer staging (2021)

Metastatic disease according to [<sup>18</sup>F]PSMA-1007 PET/CT was associated with ISUP grade and PSA level. This is the largest study using [<sup>18</sup>F]PSMA-1007 PET/CT to confirm a positive correlation of PSA level, ISUP grade and stage with primary prostate tumour SUVmax.
Id2 Collaborates with Id3 To Suppress Invariant NKT and Innate-like Tumors (2017)

Inhibitor of DNA binding (Id) proteins, including Id1-4, are transcriptional regulators involved in promoting cell proliferation and survival in various cell types. Although upregulation of Id proteins is associated with a broad spectrum of tumors, recent studies have identified that Id3 plays a tumor-suppressor role in the development of Burkitt's lymphoma in humans and hepatosplenic T cell lymphomas in mice. In this article, we report rapid lymphoma development in <i>Id2</i>/<i>Id3</i> double-knockout mice that is caused by unchecked expansion of invariant NKT (iNKT) cells or a unique subset of innate-like CD1d-independent T cells. These populations began to expand in neonatal mice and, upon malignant transformation, resulted in mortality between 3 and 11 mo of age. The malignant cells also gave rise to lymphomas upon transfer to <i>Rag</i>-deficient and wild-type hosts, reaffirming their inherent tumorigenic potential. Microarray analysis revealed a significantly modified program in these neonatal iNKT cells that ultimately led to their malignant transformation. The lymphoma cells demonstrated chromosome instability along with upregulation of several signaling pathways, including the cytokine-cytokine receptor interaction pathway, which can promote their expansion and migration. Dysregulation of genes with reported driver mutations and the NF-κB pathway were found to be shared between <i>Id2</i>/<i>Id3</i> double-knockout lymphomas and human NKT tumors. Our work identifies a distinct premalignant state and multiple tumorigenic pathways caused by loss of function of Id2 and Id3. Thus, conditional deletion of <i>Id2</i> and <i>Id3</i> in developing T cells establishes a unique animal model for iNKT and relevant innate-like lymphomas.
Occurrence and Phenotypic Characterization of Yersinia ruckeri Strains with Biofilm-Forming Capacity in a Rainbow Trout Farm (2002)

The presence of Yersinia ruckeri in a French fish farm was investigated. Y. ruckeri was isolated mainly from algae and sediment samples rather than from water. Twenty-two Y. ruckeri isolates were obtained, and three strains were distinguished by enterobacterial repetitive intergenic consensus PCR amplification. These strains were able to adhere to solid supports. This characteristic was correlated with flagellum-mediated motility. Killing experiments showed that sessile cells were more resistant to oxolinic acid than their planktonic counterparts. Our results demonstrate that surface colonization of fish farm tanks by Y. ruckeri biofilms is a potential source of recurrent infection for extended periods of time.
Assessment by molecular mechanics of the preferred conformations of the sixteen C(4)–C(6) and C(4)–C(8) linked dimers of (+)-catechin and (–)-epicatechin with axial or equatorial dihydroxyphenyl substituents at C(2) (1987)

The molecular mechanics program MM2 has been employed for a conformational analysis of 16 dimers of (+)-catechin and/or (–)-epicatechin that have axial dihydroxyphenyl substituents at C(2). Monomer units are linked by 4α–6, 4α–8, 4β–6, and 4β–8 interflavan bonds. There is a two-fold rotation about the bond between monomer units, as has previously been shown to be the case for dimers with equatorial dihydroxyphenyl substituents at C(2). The exact value of the dihedral angle at the local minima is influenced by the stereochemistry at both C(3) and C(4) of the unit that is bonded through C(4). Heterocyclic rings occupy a range of conformations that parallel those seen when the substituents at C(2) occupy equatorial positions. Variations in the heterocyclic ring conformations are obtained by co-ordinated motion of C(2) and C(3) with respect to the mean plane of the fused atomic ring system.
Detection of Privilege Escalation for Linux Cluster Security (2005)

Cluster computing systems can be among the most valuable resources owned by an organization. As a result, they are high profile targets for attackers, and it is essential that they be well-protected. Although there are a variety of security solutions for enterprise networks and individual machines, there has been little research focused specifically on securing cluster systems despite their great importance. NVisionCC is a multifaceted security solution for cluster systems built on the Clumon cluster monitoring infrastructure developed at the National Center for Supercomputing Applications. This paper describes an NVisionCC component designed to detect unauthorized privilege escalation. This component enables security monitoring software to detect an entire class of attacks in which an authorized local user of a cluster is able to improperly elevate process privileges by exploiting some software vulnerability. Detecting this type of attack is one of many facets in an all-encompassing cluster security solution.
Recent progress in synthesis for testability (2002)

Describes recent work involving the automatic synthesis of VLSI circuits with testability considerations. The first put of this paper explores the potential for logic synthesis to allow designers to more comprehensively test circuits while simultaneously diminishing the need for fault simulation and automatic test pattern generation. Logic optimization procedures can be used to produce circuits that are completely testable for single stuck-at faults. Testing for faults such as multiple stuck-at faults, gate delay faults and path delay faults is a greater challenge, but logic synthesis and optimization procedures can produce circuits that have high degrees of testability under these models as well. For each of these fault models test vectors can be produced as a by-product of the synthesis process and vector minimization algorithms can be used in the place of fault simulation to reduce the size of the test vector sets. The second part of the paper considers the difficult problem of synthesizing sequential circuits with high degrees of single stuck-at fault coverage without incurring the area and performance penalty of scan registers. Initial results at combining synthesis for testability approaches with register-transfer level automatic test-pattern generation to produce vector sets that give complete single stuck-at fault coverage without the use of scan.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Programming by Refinement, as Exemplified by the SETL Representation Sublanguage (1979)

“Pure” SETL is a language of very high level allowing algorithms to be programmed rapidly and succintly. SETL's representation sublanguage adds a system of declarations which allow the user of the language to control the data structures that will be used to implement an algorithm which has already been written in pure SETL, so as to improve its efficiency. Ideally no rewriting of the algorithm should be necessary. The facilities provided by the representation sublanguage and the run-time data structures that it can generate are described; based on this a heuristic which uses some of the methods of global program analysis and which should be capable of selecting an acceptably efficient representation automatically is given.
Assessing Distraction Potential of Augmented Reality Head-Up Displays for Vehicle Drivers (2019)

The proposed methods can be applied by designers of in-vehicle AR HUD interfaces and be leveraged by designers of AR user interfaces in general.
Risk of Aneurysm Recurrence in Patients With Clipped Cerebral Aneurysms (2001)

This study shows that the annual rate of de novo aneurysm formation is relatively high (0.89%) and that the cumulative risk becomes significant after 9 years. In consideration of the fatality rate of SAH, follow-up angiography may be indicated for patients with clipped aneurysms 9 to 10 years after surgery.
Clases lógicas y colectivas: ¿Dos modos de organización jerárquica? (1989)

ResumenTras analizar los principios estructurales inherentes a las posibles formas de organización jerárquica de lo real, se pasa a comprobar empíricamente las diferencias de ejecución en tareas de inclusión, que se pueden encontrar en nuestros escolares, cuando la naturaleza de las relaciones parte-todo implícitas en las mismas se presenta bajo la forma de colecciones (referentes de nombres colectivos) o de clases (referentes de nombres genéricos). Los resultados no parecen evidenciar diferencias significativas en la resolución de problemas que impliquen jerarquización de relaciones (inclusión).
Integration of heparin-binding protein and interleukin-6 in the early prediction of respiratory failure and mortality in pneumonia by SARS-CoV-2 (COVID-19) (2020)

Abstract Purpose Recent publications on the probable role of heparin-binding protein (HBP) as a biomarker in sepsis prompted us to investigate its diagnostic and prognostic performance in severe COVID-19 Methods HBP and IL-6 were measured by immunoassays at admission and on day 7 in 178 patients with pneumonia by SARS-CoV-2. Patients were classified into non-sepsis and sepsis as per the Sepsis-3 definitions and were followed-up for the development of severe respiratory failure (SRF) and for outcome. Results were confirmed by multivariate analyses. Results HBP was significantly higher in patients classified as having sepsis and was negatively associated with the oxygenation ratio and positively associated with creatinine and lactate. Logistic regression analysis evidenced admission HBP more than 18 ng/ml and IL-6 more than 30 pg/ml as independent risk factors for the development of SRP. Their integration prognosticated SRF with respective sensitivity, specificity, positive predictive value and negative predictive 59.1%, 96.3%, 83.9% and 87.8%. Cox regression analysis evidenced admission HBP more than 35 ng/ml and IL-6 more than 30 pg/ml as independent risk factors for 28-day mortality. Their integration prognosticated 28-day mortality with respective sensitivity, specificity, positive predictive value and negative predictive 69.2%, 92.7%, 42.9% and 97.5%. HBP remained unchanged over-time course. Conclusion A prediction score of the disposition of patients with COVID-19 is proposed taking into consideration admission levels of IL-6 and HBP. Using different cut-offs the score may predict the likelihood for SRF and for 28-day outcome.