gebhart/patrepeval huggingface dataset:
GP attitudes to male reproductive and sexual health education and promotion. A qualitative study. (2003)

A total of 27 GPs from four Victorian divisions of general practice (three metropolitan and one rural) participated in three focus groups. Key themes from the data were identified after analysis of the data by three researchers. General practitioners indicated that a clinical demand for men's health services needed to be generated in order for GPs to be interested in professional development. They suggested community education providing general information to men about sexual and reproductive health issues and emphasising the importance of accessing their GP for health checks. However, due to a lack of information for GPs about some areas of male sexual and reproductive health, e.g., androgen deficiency and male infertility, a case based practical approach to GP education was recommended. General practitioners also requested concrete information, current specialist recommendations and details of locally available services working in men's health.
Effect of tauroursodeoxycholic acid on biliary lipid composition. A dose-response study. (1995)

Tauroursodeoxycholic acid has been proposed for the treatment of hepatobiliary disease, but data on the enrichment of biliary tauroursodeoxycholic acid pool and on changes of biliary lipids after administration of the compound are scarce. We studied the composition of biliary lipids in a series of 33 patients with radiolucent stones, before and after treatment with tauroursodeoxycholic acid, 3.5 - 16.6 mg/kg/day for 4 - 6 weeks. Duodenal bile was collected with the Entero-Test after gallbladder contraction. Tauroursodeoxycholic acid administration produced the following dose-dependent effects: a linear decrease of cholesterol saturation (r = 0.59, p < 0.001); a non-linear increase of the percent of ursodeoxycholic acid in bile (r = 0.59, p < 0.001); a non-linear increase of the fraction of ursodeoxycholate conjugated with taurine. At the dose of 11 mg/kg per day, cholesterol saturation was 80%, ursodeoxycholic acid represented about 45% of biliary bile acids, and about half of UDCA was conjugated with taurine. Biliary bile acids were repeatedly measured in 6 patients during long-term treatment with 9.7 - 12.1 mg/kg. The fraction of tauroursodeoxycholic acid decreased progressively from 67.6% +/- 10.5 to 29.1% +/- 5. Tauroursodeoxycholic acid is as effective as ursodeoxycholic acid on a molar basis in reducing biliary cholesterol saturation and in enriching bile with ursodeoxycholate. Moreover, tauroursodeoxycholic acid administration is associated with higher concentrations of tauroconjugates in the bile than those previously reported by feeding the free bile acid.
Problems (1999)

Ismor Fischer, Ice B. Risteski, Michael H. Brill, Western Maryland College Problems Group, Jiro Fukuta, Michael McGeachie, Stan Wagon, Ira Rosenholtz, 1996 MathCamp Students, Seth Zimmerman, Erwin Just, John Christopher, Marty Getz, Dixon Jones, Benjamin G. Klein, Arthur L. Holshouser, Roger Zarnowski, Charles Diminnie, Homer White, Robert Bailey, Gao Peng, Ken Richardson, Problems, Mathematics Magazine, Vol. 72, No. 2 (Apr., 1999), pp. 148-155
Germplasm Screening Using DNA Markers and Genome-Wide Association Study for the Identification of Powdery Mildew Resistance Loci in Tomato (2022)

Powdery mildew (PM), caused by <i>Oidium</i> spp. in tomato, is a global concern that leads to diminished yield. We aimed to evaluate previously reported DNA markers linked to powdery mildew resistance (PMR) and identify novel quantitative trait loci (QTLs) for PMR through a genome-wide association study in tomato. Sequencing analysis of the internal transcribed spacer (ITS) of a PM strain (PNU_PM) isolated from Miryang, Gyeongnam, led to its identification as <i>Oidium neolycopersici</i>. Thereafter, a PM bioassay was conducted for a total of 295 tomato accessions, among which 24 accessions (4 <i>S. lycopersicum</i> accessions and 20 accessions of seven wild species) showed high levels of resistance to PNU_PM. Subsequently, we genotyped 11 markers previously linked to PMR in 56 accessions. PMR-specific banding patterns were detected in 15/22 PMR accessions, while no such bands were observed in the powdery mildew-susceptible accessions. The genome-wide association study was performed using TASSEL and GAPIT, based on the phenotypic data of 290 accessions and 11,912 single nucleotide polymorphisms (SNPs) obtained from the Axiom<sup>®</sup> Tomato SNP Chip Array. Nine significant SNPs in chromosomes 1, 4, 6, 8, and 12, were selected and five novel QTL regions distinct from previously known PMR-QTL regions were identified. Of these QTL regions, three putative candidate genes for PMR were selected from chromosomes 4 and 8, including two nucleotide binding site-leucine rich repeat class genes and a receptor-like kinase gene, all of which have been identified previously as causative genes for PMR in several crop species. The SNPs discovered in these genes provide useful information for understanding the molecular basis of PMR and developing DNA markers for marker-assisted selection of PMR in tomato.
Impact of COVID-19-Mediated Olfactory Loss on Quality of Life (2022)

QoL appears to be impaired in patients with long-lasting COVID-19 olfactory disorders several months after overcoming acute symptoms, even if olfaction has normalized. However, the impairment is not more pronounced than in patients with other postviral olfactory disorders of the same duration.
A new cross-linking strategy: protein interaction reporter (PIR) technology for protein–protein interaction studies (2010)

Chemical cross-linking coupled with mass spectrometry, an emerging approach for protein topology and interaction studies, has gained increasing interest in the past few years. A number of recent proof-of-principle studies on model proteins or protein complex systems with improved cross-linking strategies have shown great promise. However, the heterogeneity and low abundance of the cross-linked products as well as data complexity continue to pose enormous challenges for large-scale application of cross-linking approaches. A novel mass spectrometry-cleavable cross-linking strategy embodied in Protein Interaction Reporter (PIR) technology, first reported in 2005, was recently successfully applied for in vivo identification of protein-protein interactions as well as actual regions of the interacting proteins that share close proximity while present within cells. PIR technology holds great promise for achieving the ultimate goal of mapping protein interaction network at systems level using chemical cross-linking. In this review, we will briefly describe the recent progress in the field of chemical cross-linking development with an emphasis on the PIR concepts, its applications and future directions.
Thyroid-Specific Expression of Cholera Toxin A1 Subunit Causes Thyroid Hyperplasia and Hyperthyroidism in Transgenic Mice* (1997)

Thyroid cell growth and function are regulated by hormones and growth factors binding to cell surface receptors that are coupled via G proteins, Gs and Gq, to the adenylyl cyclase and phospholipase C signal transduction systems, respectively. Activating mutations of the TSH receptor and G alpha s have been documented in subsets of thyroid neoplasms. To test the oncogenic potential of activated G alpha s in transgenic mice, we used the cholera toxin A1 subunit that constitutively activates G alpha s and used the rat thyroglobulin gene promoter for targeting this transgene (TGCT) to thyroid follicular cells. Three (M1392, F1358, and F1286) of six founders identified were able to transmit the transgene to their offspring and thyroid glands from these mice contained elevated levels of cAMP. Concentrations of serum thyroxine were elevated as early as 2 months of age (M 1392 and F 1286). F1358 mice were euthyroid until 8 months of age, at which time they developed hyperthyroidism. All three TGCT lines developed thyroid hyperplasia independent of their thyroxine levels. DNA image analysis of thyroid follicular cells from both the hyper and euthyroid mice showed that DNA index and "S+G2/M" phase were increased compared with normal, changes similar to that seen in poor prognosis human carcinomas. These data suggest that the G alpha s-adenylyl cyclase-cAMP pathway has an important role in thyroid hyperplasia and the transgenic mouse models reported herein will allow further examination of the role of this pathway in thyroid oncogenesis.
Weak Ion–Molecule Interactions in the Gas Phase: A High-Pressure Mass Spectrometry and Computational Study of Chloride–Alkane Interactions (2013)

High-pressure mass spectrometric equilibrium experiments and electronic structure calculations have been carried out to investigate the energetics of the interactions of chloride ion with a series of normal alkanes and cycloalkanes in the gas phase. The structures of the complexes obtained from the electronic structure calculations provide considerable insight into the nature of the interaction between the negatively charged ion and the alkanes, which has the character of a purely ion-induced dipole interaction. The structural information also shows how the charged species affect the confirmation of the normal alkanes.
Normal mode analysis of diffusion in multicomponent electrolyte solutions. 1. Nonassociating electrolytes (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNormal mode analysis of diffusion in multicomponent electrolyte solutions. 1. Nonassociating electrolytesPierre Turo, Louisiane Orcil, Marius Chemla, and Reginald MillsCite this: J. Phys. Chem. 1982, 86, 20, 4062–4067Publication Date (Print):September 1, 1982Publication History Published online1 May 2002Published inissue 1 September 1982https://pubs.acs.org/doi/10.1021/j100217a035https://doi.org/10.1021/j100217a035research-articleACS PublicationsRequest reuse permissionsArticle Views57Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
High-Speed Optical Vector and Matrix Operations Using a Semiconductor Laser (2013)

Using induced transient dynamics of a standard telecommunication laser, we perform optical computation at high data rates. Employing time-multiplexing, we emulate a nonlinear photonic network via a single laser diode. Based on the induced dynamics of the network, a machine learning technique is implemented. We compute the multiplication of a scalar with a vector, vector dot and cross products, and the multiplication of a matrix and a vector, using the same system. Information is injected all-optically at a rate of 5 GSamples/s, allowing for up to 5·10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">8</sup> operations per second.
Standardized Uptake Value Ratio-Independent Evaluation of Brain Amyloidosis (2016)

The assessment of in vivo18F images targeting amyloid deposition is currently carried on by visual rating with an optional quantification based on standardized uptake value ratio (SUVr) measurements. We target the difficulties of image reading and possible shortcomings of the SUVr methods by validating a new semi-quantitative approach named ELBA. ELBA involves a minimal image preprocessing and does not rely on small, specific regions of interest (ROIs). It evaluates the whole brain and delivers a geometrical/intensity score to be used for ranking and dichotomic assessment. The method was applied to adniimages 18F-florbetapir images from the ADNI database. Five expert readers provided visual assessment in blind and open sessions. The longitudinal trend and the comparison to SUVr measurements were also evaluated. ELBA performed with area under the roc curve (AUC) = 0.997 versus the visual assessment. The score was significantly correlated to the SUVr values (r = 0.86, p < 10-4). The longitudinal analysis estimated a test/retest error of ≃2.3%. Cohort and longitudinal analysis suggests that the ELBA method accurately ranks the brain amyloid burden. The expert readers confirmed its relevance in aiding the visual assessment in a significant number (85) of difficult cases. Despite the good performance, poor and uneven image quality constitutes the major limitation.
Quality Characteristics of Sulgidduk Containing Added Tomato Powder (2008)

The purpose of this study was to determine the most desirable mixture ratio of tomato powder to rice flour for the preparation of tomato Sulgidduk(Sulgidduk containing tomato powder). The moisture contents of samples ranged from 38% to 42%. The L-value decreased, while a- and b-values increased, with increasing amounts of added tomato powder. Also, the pH of samples decreased with increasing amounts of tomato powder. In the mechanical evaluation of physical properties, hardness, adhesiveness, cohesiveness and springiness decreased with increasing tomato powder content. And throughout the storage period, gumminess and chewiness decreased. Based on sensory evaluations, the tomato power intensified the color, flavor, sweetness and sourness of the Sulgidduk. The sample containing 6% tomato powder had the highest softness, moistness, chewiness and the overall-acceptability scores. Consequently, the addition of 6% tomato powder to the rice flour was determined to be the best formula for tomato Sulgidduk in terms of the sensory qualities such as softness, moistness, chewiness and overall-acceptability.
Laser Probe Investigation of Guided Acoustic Interface Waves in Differentially Poled Ceramics (1981)

Transition zones between regions of opposite polarization in differentially poled piezoceramics are demonstrated as suitable waveguide structures for the propagation of acoustic interface waves. A heterodyne laser probe has been implemented in a study of these interface waves, and measurements of the acoustic field distribution relative to the transition zone have been made. Finally, the interface wave is shown to possess the analytical form developed by Maerfeld and Tournois [11 in the case where the transition zone is very narrow compared to acoustic wavelength.
Frequency comparisons of Sr, Yb, and Hg based optical lattice clocks and their applications (2015)

We report recent progress of optical lattice clocks with strontium, ytterbium and mercury atoms with an emphasis on their synchronous frequency comparison inside a laboratory and inter-laboratories connected by a phase-stabilized fiber link.
Study of Free Electron Laser(FEL) using the Electron Storage Ring "NIJI-IV". (1993)

We have constructed a racetrack-type compact electron storage ring "NIJI-IV " for UV FEL . The ring has a hexagonal configuration with two 7.25 m-long straight sections, though its circumference is 29.6 m. A 6.3 m optical klystron (OK) for high FEL gain was installed in one of the long straight sections. The experimental setup for FEL lasing was started at the end of April 1992. The setup on the ring with the OK and the cavity mirror alignment have been completed. The FEL lasings using the NIJI-IV were accomplished at 595^-589 nm on August 18 , 1992 and at 488 nm on September 18, 1992. The final development target is stable FEL lasing in the UV range .
Conditional QTL Mapping of Sedimentation Volume on Seven Quality Traits in Common Wheat (2013)

To evaluate the possible genetic interrelationships between flour components and the sedimentation volume (SD), a doubled haploid (DH) population comprising 168 lines were used to identify the conditional quantitative trait loci (QTLs) for SD in three environments. Ten additive QTLs and 15 pairs of epistatic QTLs were detected for SD through unconditional and conditional QTL mapping. Three major additive QTLs were detected for SD conditioned on the seven quality traits. Two additive QTLs were found to be independent of these traits. Three additive QTLs were suppressed by three of the seven traits because of non-detection in unconditional mapping. Three pairs of epistatic QTLs were completely affected by the seven traits because of detection in unconditional mapping but no-detection in conditional mapping. Twelve pairs of epistatic QTLs were detected in conditional mapping. Our results indicated that conditional mapping could contribute to a better understanding of the interdependence of different and closely correlated traits at the QTL molecular level, especially some minor QTLs were found. The conditional mapping approach provides new insights that will make it possible to avoid the disadvantages of different traits by breeding through molecular design.
Synthesis and evaluation of liquid amine-terminated polybutadiene rubber and its role in epoxy toughening (2005)

Epoxy resin is widely used for coatings, adhesives, castings, electrical insulation materials, and other applications. However, unsolved problems still remain in its applications. The main problem is low toughness: cured epoxy resin is rather brittle, with poor resistance to the propagation of cracks derived from the internal stress generated by shrinkage in the cooling process from cure temperature to room temperature. The objective of this study was to improve the flexibility and toughness of diglycidyl ether of bisphenol A based epoxy resin with a liquid rubber. For this purpose, amine-terminated polybutadiene (ATPB) was synthesized. The product was characterized by Fourier transform infrared and NMR spectroscopy and elemental analysis. ATPB-modified epoxy networks were made by curing with an ambient-temperature curing agent, triethylene tetramine. We varied the epoxy/liquid rubber compositions to study the effect of toughener concentration on the impact and thermal properties. Higher mechanical properties were obtained for epoxy resins toughened with 1 phr ATPB. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 96: 2446–2453, 2005
Efficacy and Safety of Nebivolol in Elderly Heart Failure Patients with Impaired Renal Function: Insights from the SENIORS Trial (2009)

Nebivolol is safe and has a similar effect in elderly HF patients with mild or moderate renal impairment.
Cytotoxic T-cell epitopes in HIV/SIV infection (1993)

From the Laboratoire d'Immunologie et d'Oncologie des Maladies Retrovirales, Unité INSERM U152, Institut Cochin de Génétique Moléculaire, Paris, France *Infectious Disease Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
0D-2D and 1D-2D Semiconductor Hybrids Composed of All Inorganic Perovskite Nanocrystals and Single-Layer Graphene with Improved Light Harvesting (2022)

In this study, inorganic cesium lead iodide (CsPbI<sub>3</sub>) perovskite nanoparticles (PNPs) and perovskite nanowires (PNWs) with single-layer graphene (SLG) are combined to obtain 0D–2D PNP–SLG and 1D–2D PNW–SLG hybrids with improved light harvesting. Time-resolved single-nanostructure photoluminescence studies of PNPs, PNWs, and related hybrids reveal (i) quasi-two-state photoluminescence blinking in PNPs, (ii) highly polarized photoluminescence emitted by PNWs and (iii) efficient interfacial electron transfer between perovskite nanostructures and SLG in both PNP–SLG and PNW–SLG hybrids. Thus, doping of poorly absorbing, highly conductive SLG with perovskite nanocrystals and nanowires provides a simple, yet efficient path to obtain hybrids with increased light-harvesting properties for potential utilization in the next-generation photodetectors and photovoltaic devices, including polarization sensitive photodetectors.
Spectral and temporal modulation features for phonetic recognition (2009)

Recently, the modulation spectrum has been proposed and found to be a useful source of speech information. The modulation spectrum represents longer term variations in the spectrum and thus implicitly requires features extracted from much longer speech segments compared to MFCCs and their delta terms. In this paper, a Discrete Cosine Transform (DCT) analysis of the log magnitude spectrum combined with a Discrete Cosine Series (DCS) expansion of DCT coefficients over time is proposed as a method for capturing both the spectral and modulation information. These DCT/DCS features can be computed so as to emphasize frequency resolution or time resolution or a combination of the two factors. Several variations of the DCT/DCS features were evaluated with phonetic recognition experiments using TIMIT and its telephone version (NTIMIT). Best results obtained with a combined feature set are 73.85% for TIMIT and 62.5% for NTIMIT. The modulation features are shown to be far more important than the spectral features for automatic speech recognition and far more noise robust.
Improved yield models for fault-tolerant memory chips (1993)

Several improvements in the method of yield modeling for memory chips with redundancy are described. First, a direct method of translating defect-monitor data to memory-chip fault eliminates the need for yield-model formulas. This makes possible the accurate modeling of the faults that can be fixed with redundant circuits or other fault-tolerance techniques. A second improvement results from the use of separate frequency distributions for different failure mechanisms instead of the multivariate distributions used until now. The yields of array islands with their own redundant word and bit lines are combined using a new yield formula. Examples of the use of this technique for dynamic-random-access-memory (DRAM) chips are given. A simplified pragmatic approximation technique that appears to be in good agreement with experimental data is also discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Feminism, Fiction and Contract Theory: Trollope's He Knew He Was Right (1994)

Anthony Trollope wrote He Knew He Was Right from November 1867 to June 1868, years during which a bill to grant property rights to married women under common law was being fiercely debated in both Parliament and the press. The first Married Women's Property Act passed in 1870.1 As an editor and writer for popular periodicals, and as a politician manque who actually stood for Parliament in No vember 1868, Trollope was certain to have been familiar with argu ments on both sides of this issue. He Knew He Was Right, an explora tion of male authority and women's rights within marriage—core is sues in arguments over married women's property—is Trollope's timely contribution to this debate. I attempt to make explicit the na ture of this contribution by showing how He Knew He Was Right in tersects with the broader cultural discourse of contract, which informs Victorian Feminist arguments, and which was central to an ideal of married love.