gebhart/patrepeval huggingface dataset:
Optimum Model Selecting Tool of Pneumatic System (2002)

In designing pneumatic systems, how to select matched models which meet requirements easily, swiftly and appropriately becomes increasingly important from the point of view to reduce the designing time and cost.In this paper, an optimum model selection tool for pneumatic systems named Pneumatic Model Selection Program (PMSP) will be introduced. If a user inputs some requirements, the program automatically selects matched models such as cylinder, valve, speed controller, piping and shock absorber. If the user inputs a circuit and part number of components, the program calculates. the dynamic performance of the system and indicates various characteristics such as full stroke time, stroke end velocity and air consumption. Besides, the user can also calculate the cushion ability of the cylinder and the condensation probability of the system by using this program.
Distance Protection Performance in AC Power System With Back-to-Back Converter Interface (2019)

In renewables and asynchronous interconnection, converter interface plays a pertinent role for appropriate integration to the power grid. Nevertheless, implementation of these power electronic based converters introduces technical challenges considering an AC power system. In this study, the effects of converter interface on protection devices, specifically distance protection relays, have been investigated. An evaluation of the efficacy of these distance relays is performed considering abnormal conditions on the AC grid system interfaced with power electronic converters. Further, a three different case scenario is presented for a back-to-back converter that has been designed on MATLAB Simulink based on AL-FADHLI substation. Based on this investigation and observations, it can be emphasized that during a faulty condition, if the converters are the predominant power source at the interfacing point, the distance protection relays are negatively affected. Apart from this, no other associated technical complications are noticed to have an impact on the performance of these protection relays.
GENERAL DYNAMIC MATHEMATICAL MODELING OF HETEROGENEOUS ZIEGLER-NATTA AND METALLOCENE CATALYZED COPOLYMERIZATION WITH MULTIPLE SITE TYPES AND MASS AND HEAT TRANSFER RESISTANCES (1995)

Homogeneous and heterogeneous Ziegler-Natta catalyzed copolymerizations are described by a novel dynamic mathematical model that considers the presence of multiple catalytic site types and mass and heat transfer effects on polymerization rate and polymer properties. Soluble catalysts are regarded as a special case of the general modelling where only one or two site types are present and mass and heat transfer resistances are considered negligible. The Stockmayer bivariate distribution will be used to predict distributions of chain length and chemical composition of copolymer products.
Potentia Hazards of Combination Immunotherapy in the Treatment of Experimental Septic Shock (1996)

Using an actual infection model of Pseudomonas aeruginosa sepsis in neutropenic rats, the potential utility of a combination anticytokine approach for the treatment of sepsis was tested. A dimeric tumor necrosis factor binding protein (TNF-BP) consisting of two soluble recombinant human TNF type 1 receptors linked with polyethylene glycol was used with recombinant human interleukin-1 receptor antagonist (IL-1ra). Despite having levels of bacteremia and endotoxemia similar to the control group (survivors, 0/18), 30% of IL-1ra-treated animals survived (P < .05); 31% of TNF-BP-treated animals survived (P < .01). Unexpectedly, the combination of IL-1ra plus TNF-BP proved to be uniformly fatal (survivors, 0/20). Endotoxin (P < .0001) and bacteremia (P < .01) levels were >10-fold higher than levels in animals treated with IL-1ra alone, TNF-BP alone, or placebo. Disseminated microabscesses in major organs were found in animals treated with combination immunotherapy. Combination anticytokine therapy may exacerbate systemic infection and worsen outcome in experimental sepsis.
The effects of sterilisation on the properties of calcium sulphate hemihydrate (1973)

Abstract Plaster of Paris has been recommended as a suitable bone substitute material. In this project both calcined and autoclaved plasters have been prepared and the effects of sterilisation on their properties determined. Samples of plaster suitable for use in animal experimentation have been prepared.
Wavefront shaping based on three-dimensional optoacoustic feedback (2015)

Wavefront shaping techniques have recently evolved as a promising tool to control the light distribution in optically-scattering media. These techniques are based on spatially-modulating the phase of an incident light beam to create positive interference (focusing) at specific locations in the speckle pattern of the scattered wavefield. The optimum phase distribution (mask) of the spatial light modulator that allows focusing at the target location(s) is determined iteratively by monitoring the light intensity at such target. In this regard, optoacoustic (photoacoustic) imaging may provide the convenient advantage of simultaneous feedback information on light distribution in an entire region of interest. Herein, we showcase that volumetric optoacoustic images can effectively be used as a feedback mechanism in an iterative optimization algorithm allowing controlling the light distribution after propagation through a scattering sample. Experiments performed with absorbing microparticles distributed in a three-dimensional region showcase the feasibility of enhancing the light intensity at specific points. The advantages provided by optoacoustic imaging in terms of spatial and temporal resolution anticipate new capabilities of wavefront shaping techniques in biomedical optics.
A comparative study of the photocatalytic properties of CuS nanotubes and nanoparticles by hydrothermal method (2017)

Copper sulfide nanotubes and nanoparticles have been successfully synthesized by a hydrothermal process at 160 °C for 10 h, employing copper chloride (CuCl 2 ·2H 2 O) and thioacetamide as starting materials, polyethylene glycol 400 as surfactant. The products are characterized by X-ray power diffraction, scanning electron microscopy, UV–vis spectroscopy and fluorescence spectroscopy, respectively. The results show that both CuS nanotubes and nanoparticles belong to the hexagonal phase CuS and the morphologies of the products are greatly influenced by the surfactant, reactant molar concentration and reactant molar ratio. The photocatalytic properties of the CuS nanotubes and nanoparticles have been evaluated via photocatalytic degradation of organic dye and reduction of aqueous Cr (VI) under UV light irradiation. The CuS nanotubes with smooth inside and coarse outside present higher photocatalytic performance than the CuS nanoparticles.
Calorimetric study of protein transitions in human erythrocyte ghosts (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCalorimetric study of protein transitions in human erythrocyte ghostsWilliam M. Jackson, John Kostyla, John H. Nordin, and John F. BrandtsCite this: Biochemistry 1973, 12, 19, 3662–3667Publication Date (Print):September 1, 1973Publication History Published online1 May 2002Published inissue 1 September 1973https://pubs.acs.org/doi/10.1021/bi00743a014https://doi.org/10.1021/bi00743a014research-articleACS PublicationsRequest reuse permissionsArticle Views57Altmetric-Citations47LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Comparing conceptual modeling techniques (2008)

The empirical literature comparing entity relationship and object-oriented modeling techniques, while vibrant, has often yielded equivocal findings. This review employs Norman's (1986) Theory of Action to distinguish between model creation and comprehension studies, and applies and extends the theoretical framework proposed by Gemino and Wand (2004) to highlight and detail several issues that may need further exploration if consistent results in this stream are to be realized. Specifically, this paper explores why and how issues of ontological foundation, training, equivalence of conceptual models, and modeling practices may result in differences between alternative modeling techniques. A comprehensive picture of this literature is provided and a number of potential avenues for future research are proposed.
A Novel Hydrolytic Activity of Tri-Functional Geranylgeranyl Pyrophosphate Synthase in Haematococcus pluvialis (2018)

Under environmental stresses, Haematococcus pluvialis accumulates large amounts of carotenoids. Scale of carotenoid biosynthesis depends on availability of geranylgeranyl pyrophosphate (GGPP) precursor, which is supplied by GGPP synthase (GGPPS) through sequential 1'-4 condensation of three isopentenyl pyrophosphates (IPPs) into dimethylallyl pyrophosphate (DMAPP). Using IPP and DMAPP as substrates, a tri-functional HpGGPPS was identified in this study to promiscuously synthesize allylic prenyl pyrophosphates (PPPs), e.g. C10 geranyl pyrophosphate (GPP), C15 farnesyl pyrophosphate (FPP), and C20 GGPP. Intriguingly, HpGGPPS can utilize GPP or FPP as a single substrate to synthesize GGPP by hydrolyzing the allylic PPP substrate into C5 IPP. Transcription of HpGGPPS and key carotenogenesis genes, morphological transformation, and carotenoid biosynthesis were differentially induced by environmental stresses, while HpGGPPS's products were low in vivo, implying that most of PPP flux had been shunted into carotenoid biosynthesis. Hydrolyzing allylic PPP intermediates into C5 building blocks by promiscuous HpGGPPS may be a fail safe for carotenoid accumulation against environmental stress.
Methods to Advance Technology of Proton Exchange Membrane Fuel Cells (1988)

Proton exchange membrane (PEM) fuel cells showing promise of a high level of performance have, up to the present time, used electrodes containing a high platinum loading (4 mg/cm2). We report improvements in performance of PEM fuel cells utilizing electrodes with only one‐tenth of this platinum loading by (i) extension of the three‐dimensional reaction zone by incorporation of a proton conductor (Nafion) into the electrode structure; (ii) optimization of the amount of Nafion impregnated into the electrode structure; (iii) hot‐pressing the impregnated electrodes to the Nafion membrane at 120°C and 50 atm; (iv) optimal humidification of reactant gases at a temperature above that of the cell (5°C for or air and 10°–15°C for ); and (v) operation at elevated temperatures and pressures. The performance of the cells was analyzed from measurements of cell potential vs. current density and of cell potential at constant current density vs. time. Cyclic voltammetry proved to be a useful tool to ascertain the electrochemically active area of the electrodes.
Final report on the APMP comparison of capacitance at 10 pF: APMP.EM-K4.1 (2009)

A comparison of capacitance at 10 pF was conducted between thirteen participating laboratories from the Asia-Pacific region. Measurements were made between 2004 and 2006. The behaviour of the travelling artefact was consistent with a steady linear drift at a rate of approximately 0.1 ?F/F per year. Despite the wide range of capabilities within the region, the results showed good agreement between all but one of the participating laboratories. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
Supplementary Figures S1-S5 from Sarsaparilla (<i>Smilax Glabra</i> Rhizome) Extract Inhibits Cancer Cell Growth by S Phase Arrest, Apoptosis, and Autophagy via Redox-Dependent ERK1/2 Pathway (2023)

&lt;p&gt;Supplementary Figures S1-S5. Figure S1. SW shows good anticancer activity among 6 fractions from SGR. A, flow chart for preparation of SW from sarsaparilla. Figure S2. SW inhibits cancer cell growth. A, MTT screening with 11 cell lines to evaluate the growth inhibitory effect of SW. B, colony formation of AGS, HT-29, H1299, T24, PG, HepG2 and PC3 cells treated with indicated concentrations of SW. Figure S3. A, left, pictures of H22 allografts in PBS-, CTX- (80 mg/kg once a week) and SW-treated (72.7 mg once a day) groups. Figure S4. SW-induced oxidative stress is unrelated to H2O2 or NO. A, DCFH-DA labeling of intracellular ROS in SW- or solvent-treated AGS and HT-29 cells. Figure S5. ERK is downstream of GSH/GSSG imbalance upon SW treatment. A, U0126 inhibited SW-induced ERK1/2 phosphorylation. B, the effect of U0126 on SW-induced GSH/GSSG imbalance. Columns, mean; bars, SD.&lt;/p&gt;
ABAD: A Potential Therapeutic Target for A&#946;-Induced Mitochondrial Dysfunction in Alzheimers Disease (2009)

Amyloid-beta-peptide (Abetabinding to mitochondrial Abeta-binding alcohol dehydrogenase (ABAD) enzyme triggers a series of events leading to mitochondrial dysfunction characteristic of Alzheimer's disease (AD). Thus this interaction may represent a novel target for treatment strategy against AD. In this review we summarize current findings regarding the ABAD-Abeta interaction, namely structural and biophysical data, available inhibitors and more recent data from proteomic studies.
Insights Into the Aqueous History of Mars from Acid-Sulfate Weathered Phyllosilicates (2016)

Phyllosilicates on Mars are thought to have formed during Mars' earliest Noachian geologic era (approx. 4.1-3.7 Ga). Sulfate formation, on the other hand, requires more acidic conditions which are thought to have occurred later during Mars' Hesperian era (approx. 3.7-3.0 Ga). Therefore, regions on Mars where phyllosilicates and sulfates are found in close proximity to each other provide evidence for the aqueous conditions during this global transition. Both phyllosilicates and sulfates form in the presence of water and thus give clues to the aqueous history of Mars and its potential for habitability. Phyllosilicates that formed during the Noachian era would have been weathered by the prevailing acidic conditions that define the Hesperian. Therefore, the purpose of this study is to characterize the alteration products of acid-sulfate weathered phyllosilicates in laboratory experiments, focusing on the Fe/Mg-smectites commonly identified on Mars. We also compare our results to observations of phyllosilicates and sulfates on Mars in regions such as Endeavour Crater and Mawrth Vallis to understand the formation process of sulfates and constrain the aqueous history of these regions.
Derivation of Diverse Hormone-Releasing Pituitary Cells from Human Pluripotent Stem Cells (2016)

Human pluripotent stem cells (hPSCs) provide an unlimited cell source for regenerative medicine. Hormone-producing cells are particularly suitable for cell therapy, and hypopituitarism, a defect in pituitary gland function, represents a promising therapeutic target. Previous studies have derived pituitary lineages from mouse and human ESCs using 3D organoid cultures that mimic the complex events underlying pituitary gland development in vivo. Instead of relying on unknown cellular signals, we present a simple and efficient strategy to derive human pituitary lineages from hPSCs using monolayer culture conditions suitable for cell manufacturing. We demonstrate that purified placode cells can be directed into pituitary fates using defined signals. hPSC-derived pituitary cells show basal and stimulus-induced hormone release in vitro and engraftment and hormone release in vivo after transplantation into a murine model of hypopituitarism. This work lays the foundation for future cell therapy applications in patients with hypopituitarism.
Characteristics of the aragonite - calcite transistion in bivalve shells (2012)

Bivalves and gastropods contain both, calcite and aragonite within their shells (e.g.Checa &amp; Rodriguez-Navarro 2005, Checa et al. 2009). The transition between these phases is neither interlinked nor gradual, it is abrupt and occurs within a spatial range of one to two microns. &#13;\nWe have investigated in the shell of the modern oyster Crassosstrea gigas the transition zone between the calcite and the aragonite portion of the shell with TEM (Fig.1) and high-resolution EBSD (Fig. 2). Adult oyster shells are composed mainly of calcite. However, there are small areas within the shell where aragonite is present, shell portions where the muscles (the two adductor muscles, the Quenstedt muscles and the pedal muscles) are attached to the skeleton. Thus, the presence of aragonite at these skeletal parts is required for the overall function of the shell. &#13;\n
In vivo glycosylation suppresses the aggregation of amyloidogenic hen egg white lysozymes expressed in yeast (2001)

The mutant hen egg white lysozymes Ile55Thr and Asp66His, corresponding to human amyloidogenic mutant lysozymes Ile56Thr and Asp67His, respectively, were secreted in Saccharomyces cerevisiae . The amyloidogenic mutants (I55T and D66H) of hen egg white lysozymes were remarkably less soluble than that of the wild‐type protein. To enhance the secretion of these mutants, we constructed the glycosylated amyloidogenic lysozymes (I55T/G49N and D66H/G49N) having the N ‐glycosylation signal sequence (Asn‐X‐Ser) by the substitution of glycine with asparagine at position 49. The secretion of these glycosylated mutant proteins is greatly increased in S. cerevisiae , compared with that of non‐glycosylated type. Both the glycosylated mutants retained about 40% enzymatic activity when incubated at pH 7.4 for 1 h at the physiological temperature of 37°C whereas the non‐glycosylated proteins eventually lost all activity under these conditions. These results suggest that the glycosylated chains could mask the β‐strand of amyloidogenic lysozymes from the intermolecular cross‐β‐sheet association, thus improving the solubility of amyloidogenic lysozymes.
High-volume-manufacturing (HVM) of BVA&#x2122; enabled advanced package-on-package (PoP) (2015)

Bond-Via-Array (BVA™) technology has been developed to address the high density interconnect requirements of the next generation of package-on-package (PoP) solutions. This technology, while utilizing conventional assembly processes and equipment, can provide more than 1000 interconnections between the memory and the logic packages when stacked in a PoP format within a standard PoP package footprint. The vertical interconnections are achieved by utilizing well established wire-bond equipment and processes. An array of free-standing wire-bonds is formed along the periphery of the logic package to form electrical connections to the topside memory package. In this paper, key assembly process steps including free standing vertical wire-bond formation, film assist molding and fine-pitch PoP stacking will be described along with the results from manufacturing and reliability studies conducted in cooperation with 3 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">rd</sup> party equipment vendors to validate HVM readiness.
The Spirobenzylisoquinoline Alkaloids (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Spirobenzylisoquinoline AlkaloidsRuth Marie Preisner and Maurice ShammaCite this: J. Nat. Prod. 1980, 43, 3, 305–318Publication Date (Print):May 1, 1980Publication History Published online1 July 2004Published inissue 1 May 1980https://pubs.acs.org/doi/10.1021/np50009a001https://doi.org/10.1021/np50009a001research-articleACS PublicationsRequest reuse permissionsArticle Views246Altmetric-Citations34LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Tribocorrosion : application of biotribocoorosion testing protocol (2013)

International audience
Robust motion control based on projection plane in multi-degrees-of-freedom manipulator (2002)

This paper describes a novel approach to robust motion control of redundant manipulator by projection planes. In the proposed approach, the robust controller based on work space observer is employed in the selectable projection plane. Then, an adequate selection of projection planes makes it possible to simplify the controller without deteriorating the tip motion response and to obtain the desired motion in the null space of manipulator. This is one of the remarkable features of the proposed approach. The validity of the proposed controller is confirmed by several numerical simulations.
Hierarchical control of series elastic actuators through control Lyapunov functions (2014)

This paper addresses the control design problem of stabilizing both joint-angle and spring-torque control objectives in robots with series elastic actuators (SEAs). The proposed method is a hierarchical control scheme which employs rapidly exponentially stabilizing control Lyapunov functions (RES-CLFs) to obtain controllers for each tier in the scheme. The main result of the paper demonstrates that for a proper choice of controller parameters, applying the proposed controller to the SEA control system results in simultaneous exponential stability of the joint-angle and the spring-torque control objectives. Furthermore, it is shown that for a locally exponentially stable periodic orbit in the zero dynamics of the control system considered, the controller renders a corresponding orbit in the full SEA dynamics locally exponentially stable.
New basic linear algebra methods for simulation on GPUs (2011)

We have used Graphics Processing Units (GPUs) to accelerate the solution of the types of equations typically encountered in dynamic system simulators. Compared to commercial matrix solvers that run on a CPU, we realized speedups ranging from 5 (for system size ≈ 700) to 460 (for system size ≈ 5800). While calculation time for the commercial matrix solver increased with matrix size ≈ O(N)2.3, our new GPU-based Preconditioned Generalized Minimal Residual (PGM-RES) technique yielded scaling as ≈ O(N)1.2. A significant component of this performance was achieved by development of new Basic Linear Algebra routines for the NVIDIA Tesla GPU that directly address characteristics typical of matrices that describe the time domain response of naturally-coupled dynamic systems.