gebhart/patrepeval huggingface dataset:
Nonlinear distortion free fiber-based chirped pulse amplification with self-phase modulation up to 2π (2007)

We demonstrate the removal of 2pi radians of self-phase modulation (SPM) in a fiber-based chirped pulse amplification (CPA) system. Compensation of SPM distortion is achieved in the time domain by using a LiNbO(3) electro-optic phase modulator to emulate a negative nonlinear index of refraction. By synthesizing the drive waveform to the phase modulators with two RF frequencies that are phase-locked to the repetition rate of the seed laser, we achieve large phase compensations using cost-effective narrow band electronics. Our technique is simple, robust and can be readily integrated into existing fiber CPA systems.
Resistive heating of a shape memory composite: analytical, numerical and experimental study (2021)

Abstract This work investigates in detail the Joule resistive heating phenomenon of electroactive shape memory composites (SMC) when an electric current is injected at constant power. The SMC is a covalent poly( ϵ -caprolactone) network filled with 3 wt% of multiwall carbon nanotubes. The resistive heating of the SMC is studied by means of surface temperature measurements, analytical formulas and a coupled 3D thermo-electric numerical model. Analytical expressions are derived for the 2D temperature distribution within a parallelepipedic SMC, either with constant or linearly-dependent electrical resistivity. These analytical expressions can be used to investigate the influence of geometrical and material parameters in the steady-state temperature and its distribution across the sample. The results also allow one to identify the parameters that are crucial for predicting the temperature rise due to resistive heating: the temperature dependence of the resistivity has little effect on the steady-state temperature, whereas the thermal conductivity plays a significant role. The time-dependent temperature is shown to be related to the particular temperature dependence of heat capacity. Furthermore, the presence of external objects (clamps or grips) used during the shape memory cycle must be taken into consideration for a certain temperature to be reached since they result in a lower steady-state temperature and a slower resistive heating phenomenon. With the findings presented in this work, accurate resistive heating can be predicted for a SMC upon the injection of an electric current at constant power.
Decreased adipose tissue oxygenation associates with insulin resistance in individuals with obesity (2020)

BACKGROUNDData from studies conducted in rodent models have shown that decreased adipose tissue (AT) oxygenation is involved in the pathogenesis of obesity-induced insulin resistance. Here, we evaluated the potential influence of AT oxygenation on AT biology and insulin sensitivity in people.METHODSWe evaluated subcutaneous AT oxygen partial pressure (pO2); liver and whole-body insulin sensitivity; AT expression of genes and pathways involved in inflammation, fibrosis, and branched-chain amino acid (BCAA) catabolism; systemic markers of inflammation; and plasma BCAA concentrations, in 3 groups of participants that were rigorously stratified by adiposity and insulin sensitivity: metabolically healthy lean (MHL; n = 11), metabolically healthy obese (MHO; n = 15), and metabolically unhealthy obese (MUO; n = 20).RESULTSAT pO2 progressively declined from the MHL to the MHO to the MUO group, and was positively associated with hepatic and whole-body insulin sensitivity. AT pO2 was positively associated with the expression of genes involved in BCAA catabolism, in conjunction with an inverse relationship between AT pO2 and plasma BCAA concentrations. AT pO2 was negatively associated with AT gene expression of markers of inflammation and fibrosis. Plasma PAI-1 increased from the MHL to the MHO to the MUO group and was negatively correlated with AT pO2, whereas the plasma concentrations of other cytokines and chemokines were not different among the MHL and MUO groups.CONCLUSIONThese results support the notion that reduced AT oxygenation in individuals with obesity contributes to insulin resistance by increasing plasma PAI-1 concentrations and decreasing AT BCAA catabolism and thereby increasing plasma BCAA concentrations.TRIAL REGISTRATIONClinicalTrials.gov NCT02706262.FUNDINGThis study was supported by NIH grants K01DK109119, T32HL130357, K01DK116917, R01ES027595, P42ES010337, DK56341 (Nutrition Obesity Research Center), DK20579 (Diabetes Research Center), DK052574 (Digestive Disease Research Center), and UL1TR002345 (Clinical and Translational Science Award); NIH Shared Instrumentation Grants S10RR0227552, S10OD020025, and S10OD026929; and the Foundation for Barnes-Jewish Hospital.
Wine tourism: Winery visitation in the wine appellations of Ontario (2011)

This study explores various factors that encourage travel to wineries in the Ontario viticultural regions of the Niagara Peninsula, Prince Edward County, Pelee Island and Lake Erie North Shore. A convenience sample of 1309 visitors at 19 wineries revealed that the winery experience was not the primary purpose of the trip for a majority of the visitors but was a major influencer in their decision to travel to the regions. Planning typically began within three weeks of departure when friends, family and local websites provided the principal sources of information. Differences were observed among the four regions in demographic profile, motivations, influencers and consumption behavior. Proprietary tasting events and comprehensive wine tour packages including fine dining and overnight accommodation were suggested products that would attract more visitors whose on-site purchases were critical to the success of many operations.
Supplementary Table 3 from WNT16B Is a New Marker of Cellular Senescence That Regulates p53 Activity and the Phosphoinositide 3-Kinase/AKT Pathway (2023)

Supplementary Table 3 from WNT16B Is a New Marker of Cellular Senescence That Regulates p53 Activity and the Phosphoinositide 3-Kinase/AKT Pathway
Mandibular Vascular Malformations (1994)

Two cases of intraosseous vascular anomalies of the mandible--including surgical treatment and 10-year follow-up--are reported. Early aggressive resection not only resulted in resolution of symptoms and restoration of facial symmetry but also exhibited significant osseous regeneration without grafting.
Immunohistochemical staining for diagnosis of cutaneous mastocytosis (2016)

International audience
Diurnal Rhythms of Luteinizing Hormone, Follicle-Stimulating Hormone, and Testosterone Secretion before the Onset of Male Puberty1 (1999)

To investigate hormonal change before the onset of male puberty, we measured LH and FSH in serum samples drawn every 20 min for 24 h and measured testosterone hourly for 24 h. Forty-six boys (32 prepubertal and 14 pubertal) of short stature, between 4.4-19.3 yr of age, participated in this study. LH and FSH were measured using a time-resolved immunofluorometric assay, and testosterone was measured using high sensitivity RIA capable of detecting a testosterone concentration of 0.01 ng/mL. Diurnal rhythms of LH, FSH, and testosterone were apparent in all subjects, including those aged 4-5 yr. Serum LH and FSH concentrations showed night-day variation in a pulsatile fashion. The serum testosterone concentration was elevated at early morning in all subjects. Mean 24-h LH, FSH, and testosterone concentrations of prepubertal subjects who did not attain puberty for at least 3 yr were 0.10 U/L, 0.63 U/L, and 0.06 ng/mL, respectively, whereas those of prepubertal subjects who attained puberty within 1 yr (0.54 U/L, 1.68 U/L, and 0.10 ng/mL, respectively) were significantly higher. Furthermore, mean 24-h LH, FSH, and testosterone concentrations increased with developing puberty. All of the 46 subjects showed positive cross-correlation between the LH and testosterone time series. The mean lag time from the LH to the testosterone time series in the prepubertal subjects who attained puberty within 1 yr (4.7 +/- 2.4 h, mean +/- SD) was shorter than that in the prepubertal subjects who attained puberty after at least 3 yr (7.3 +/- 2.2 h). This lag time decreased with developing puberty, plateauing at 1.4 +/- 0.9 h at midpuberty. Thus, the diurnal rhythms of LH, FSH, and testosterone already exist at 4-5 yr of age; serum LH, FSH, and testosterone levels increase before the onset of puberty; and a time delay is observed between the LH and testosterone time series that decreases before the onset of puberty.
Conducting Polymer with Metal Oxide for Electrochemical Capacitor: Poly(3,4-ethylenedioxythiophene) RuO[sub x] Electrode (2001)

Electrodes made by depositing ruthenium oxide on conducting poly(3,4-ethylenedioxythiophene) (PEDT) were studied for their electrochemical and impedance properties. In acidic electrolytes the composite electrodes exhibited large capacitance due to contributions from the double-layer capacitance and the faradaic capacitance. Optimization of the thickness of the conducting polymer film and the amount of ruthenium deposition was found necessary to realize large specific capacitance. The specific capacitance based on the combined mass of was 420 F/g, and the specific capacitance based on the mass of was 930 F/g. The energy storage density of a capacitance cell constructed with a pair of electrodes reached 27.5 Wh/kg when the cell was charged to 1.0 V. The impedance analysis of the composite electrode revealed that both the double-layer capacitance and the pseudocapacitance originating from both PEDT and contribute to large specific capacitance. © 2001 The Electrochemical Society. All rights reserved.
A New Approach to Filtering Glaucoma Surgery (1966)

Research Articles| March 24 2010 A New Approach to Filtering Glaucoma Surgery R.L.H. Sampimon R.L.H. Sampimon Utrecht Search for other works by this author on: This Site PubMed Google Scholar Ophthalmologica (1966) 151 (6): 637–644. https://doi.org/10.1159/000304930 Article history Published Online: March 24 2010 Content Tools Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation R.L.H. Sampimon; A New Approach to Filtering Glaucoma Surgery. Ophthalmologica 1 June 1966; 151 (6): 637–644. https://doi.org/10.1159/000304930 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsOphthalmologica Search Advanced Search This content is only available via PDF. 1966Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Article PDF first page preview Close Modal You do not currently have access to this content.
Sharing Data on the Aquileia Heritage: Proposals for a Research Project. (2011)

Basic ideas are presented of a multi-national research project to share data about the Roman city of Aquileia employing the Information and Communication Technologies (ICT). A Consortium is proposed to manage the project, adopting the Open-source approach to the software design. The Consortium proposes a common vision of the data which we detail in the paper. There results a shared vocabulary of terms and meanings, as well as standard metadata formats to encode, classify and exchange data from whatever source. A federated system of computer resources realizes and supports the project. We also discuss the results to be realistically expected in short time of a low-cost, joint research effort.
Catalytic Synthesis of Conjugated Azopolymers from Aromatic Diazides (2021)

Conjugated polymers containing main chain azoarene repeat units are synthesized by a dinickel catalyzed N=N coupling reaction of aromatic diazides. The polymerization exhibits broad substrate scope and is compatible with heterocycles commonly featured in high performance organic materials, including carbazole, thiophene, propylenedioxythiophene (ProDOT), diketopyrrolopyrrole (DPP), and isoindigo. Copolymerizations can be carried out using monomer mixtures, and monoazide chain stoppers can be used to install well-defined end groups. Azopolymers possess unique properties owing to the functionality of the azo linkages. For example, protonation at nitrogen results in LUMO lowering and red-shifted absorption bands. Additionally, N=N bonds possess low-lying π* levels, allowing azopolymers to be reversibly reduced under mild conditions.
An umbilical data-acquisition system for measuring pressures between the foot and shoe (1990)

We have developed an umbilical data-acquisition system for measuring pressures between the foot and shoe during walking. It consists of pressure sensors in the insoles of shoes, amplifier circuits, umbilical cables, an analog-to-digital converter, and a graphics display card in an IBM PC for real-time data collection and display. The applied pressure on a sensor decreases its resistance, which causes the output voltage of the amplifier circuit to increase. We attach seven sensors to the surface of each insole of a pair of extra-depth shoes and calibrate all the sensors in the insole before and after each test using a load cell as a reference. The IBM PC samples the outputs from the sensor and the load cell and stores a piecewise linear lookup table for use in compensation for the nonlinearity of the sensor. On the PC's graphics display, two programs provide displays of foot pressures as real-time bar graphs or as analog pressure versus time curves.
Can We Rescue Thermal Wall Shear Stress Sensing? (2011)

The use of single flush-mounted thin-films for thermal sensing of wall shear stress fluctuations in turbulent flows has seen a decline, in spite of their non-intrusiveness, and the availability of microfabrication technologies to create very small films. The limitations of such single-element sensors are quite severe—their spatial resolution is not determined by their size alone, but modified by substrate heat conduction which creates variations in the effective sensor size (heat exchange area), dependent on strength and timescale of the fluctuations. Here a two-element design is investigated—with the hot-film sensor element surrounded by an electrically isolated guard heater film maintained at the same temperature as the sensor, but controlled by a separate anemometer circuit. Numerical studies are used to examine such guard heater designs over a range of shear stress values. The results show that if the sensor film center-location is biased towards the downstream end (75% and 65% of guard-heater length for water and air, respectively), with an appropriately-sized guard heater, 95% of the total heat generated in the sensing film can be transferred directly to the fluid, for strong turbulent fluctuations (Peclet number Pe &gt; 8000) when the working fluid is water.
Realizing semiconductivity by a large bandgap tuning in Bi4Ti3O12 via inserting La1-xSrxMnO3 perovskite layers (2017)

Bismuth layer structured Aurivillius oxides have long been considered as traditional ferroelectric dielectrics, and they are feasible platforms incubating magnetic, ferroelectric, photonic, microwave, etc. properties for many important applications. It has been a longstanding challenge to achieve a certain charge carrier concentration and to narrow the bandgap in such transition metal complex oxides, yet realizing that semiconductivity is necessary for potential integration functions such as junctions in oxide optoelectronic devices. By inserting La1-xSrxMnO3 into the typical Bi4Ti3O12 ferroelectric host, we demonstrate semiconductivity and large bandgap tuning in Bi4Ti3O12-La1-xSrxMnO3 (0.3 ≤ x ≤ 0.7) solid solutions, in which a minimum resistivity value of ρ = 5021 Ω·cm and an optical bandgap value of Eg = 1.97 eV are obtained. Soft X-ray absorption spectra provide Mn and Ti charge valence states, indicating an almost constant Mn3.2+ state and an increase towards Ti4+ when raising the La/Sr ratio.
Characterization of substituted piperazines able to reverse MDR inEscherichia colistrains overexpressing resistance-nodulation-cell division (RND) efflux pumps (2021)

Piperazine derivatives are good candidates as inhibitors of RND efflux pumps. They decreased the activity of RND pumps by mixed mechanisms of action. Small structural differences among the molecules can be critical in defining their behaviour.
Influence of High Energy Ball Mill Technology on Cube Texture Formation of Ni-8at.%W Alloy Substrates for YBCO-Coated Conductors (2014)

Ni8W alloy ingots were prepared by SPS technic, followed by homogenizing, cold rolling and recrystallization annealing. The influence of ball milling on cold rolling and cube texture formation of Ni8W alloy substrates was investigated during the course of preparation. Finally, high quality cube-textured Ni8W alloy substrates were successfully obtained using this powder metallurgy process, and characterized by electron backscatter diffraction technic. It indicated that the cube texture fraction was as high as 90% (&lt;10 o ) when it annealed at 1350°C for 2 h.
Markov model prediction of I/O requests for scientific applications (2002)

Given the increasing performance disparity between processors and storage devices, exploiting knowledge of spatial and temporal I/O requests is critical to achieving high performance, particularly on parallel systems. Although perfect foreknowledge of I/O requests is rarely possible, even estimates of request patterns can potentially yield large performance gains. This paper evaluates Markov models to represent the spatial patterns of I/O requests in scientific codes. The paper also proposes three algorithms for I/O prefetching. Evaluation using I/O traces from scientific codes shows that highly accurate prediction of spatial access patterns, resulting in reduced execution times, is possible.
Biomass Conversion to Hydrocarbon Fuels Using the MixAlcoTMProcess (2013)

The MixAlco<sup>TM<sup/> process converts biomass to hydrocarbons (e.g., gasoline) using the following generic steps: pretreatment, fermentation, descumming, dewatering, thermal ketonization, distillation, hydrogenation, oligomerization and saturation. This study describes the production of bio-gasoline from chicken manure and shredded office paper, both desirable feedstocks that do not require pretreatment. Using a mixed culture of microorganisms derived from marine soil, the biomass was fermented to produce a dilute aqueous solution of carboxylate salts, which were subsequently descummed and dried. The dry salts were thermally converted to raw ketones, which were distilled to remove impurities. Using Raney nickel catalyst, the distilled ketones were hydrogenated to mixed secondary alcohols ranging from C3 to C12. Using zeolite HZSM-5 catalyst, these alcohols were oligomerized to hydrocarbons in a plug -flow reactor. Finally, these unsaturated hydrocarbons were hydrogenated to produce a mixture of hydrocarbons that can be blended into commercial gasoline.
THE CONTRIBUTION OF RADIOTHERAPY TO THE TREATMENT OF MALIGNANT TUMORS (1984)

Effects of cytotoxic agent, hormone, hypoxic cell sensitizer, and radiation protector combined with radiation therapy in cancer management were analysed. The results were as follows : 1) An increase in response was seen in 25% or more of tumor nodules given radiotherapy combined with misonidazole, anoxic cell sensitizer, compared with radiotherpy alone. But the drug was also found to be neurotoxic and peripheral neuropathy.2) Evidence has been given that Amifostine may protect the mucosal damage from radiation when Amifostine prior to irradiation was administrated to patients with tumor in the head and neck or in the pelvis.3) There were no difference between five year survival of radiotherapy alone and with chemotherapy for patients with stage I Non-Hodgkin lymphoma. Chemotherapy following radiotherapy for patients with stage II was more effective treatment method than radiotherapy alone.4) Radiotherapy for patients with prostate cancer was performed to control only primary site.The success rates of local control were over 80%.The near future holds extensive promise for a combination of radiation therapy, cytotoxic chemotherapy, hormone therapy, hypoxic cell sensitizer, and radiation protectors. All of these when used in the appropriate circumstances may yield significant improvements in the therapeutic ratio and in the long-tern control of tumors.
Transition‐Metal‐Free Synthesis of N‐Hydroxy Oxindoles by an Aza‐Nazarov‐Type Reaction Involving Azaoxyallyl Cations (2016)

A novel transition-metal-free method to construct N-hydroxy oxindoles by an aza-Nazarov-type reaction involving azaoxyallyl cation intermediates is described. A variety of functional groups were tolerated under the weak basic reaction conditions and at room temperature. A one-pot process was also developed to make the reaction even more practical. This method provides alternative access to oxindoles and their biologically active derivatives.
Collagen‐Reinforced Electrospun Silk Fibroin Tubular Construct as Small Calibre Vascular Graft (2012)

None of the replacements proposed in the literature for small-calibre blood vessels (SCBV) fully satisfies the stringent requirements that these grafts have to fulfil. Here, an electrospun silk fibroin tubular construct is hybridized with type I collagen gel to produce a biomimetic SCBV graft with physiologically relevant compliance and burst pressure and optimal cytocompatibility. The hybridization of the two polymers results in the formation of a nanofibrillar hydrated matrix, where the collagen gel enhances the mechanical properties of the SF tubular construct and improves the early response of the material to in vitro cell adhesion and proliferation.
Cross-Entropy-Based Antenna Selection for Spatial Modulation (2016)

Euclidean distance optimized antenna selection (EDAS) can significantly improve the bit-error-rate (BER) performance of spatial modulation (SM) systems. However, the exhaustive search over all possible antenna subsets leads to inherently high-search complexity. In this letter, a cross-entropy-based antenna selection (CEAS) scheme is proposed, by formulating the antenna selection problem in SM as a combinatorial optimization one. Simulation results show that the proposed CEAS scheme achieves considerable reduction in search complexity, while approaching the optimal performance of exhaustive search.