gebhart/patrepeval huggingface dataset:
Purification and properties of a low-redox-potential tetraheme cytochrome c3 from Shewanella putrefaciens (1996)

Shewanella putrefaciens is a facultatively anaerobic bacterium in the gamma group of the proteobacteria, capable of utilizing a wide variety of anaerobic electron acceptors. An examination of its cytochrome content revealed the presence of a tetraheme, low-redox-potential (E'o = -233 mV), cytochrome c-type cytochrome with a molecular mass of 12,120 Da and a pI of 5.8. The electron spin resonance data indicate a bis-histidine coordination of heme groups. Reduction of ferric citrate was accompanied by oxidation of the cytochrome. The biochemical properties suggested that this protein was in the cytochrome c3 group, which is supported by N-terminal sequence data up to the first heme binding site.
Vibrating reed study of a magnetically reversible region in Nb and NbSe2 (1992)

Vibrating reed measurements of the flexural resonances of thin cantilevered Nb foils and NbSe2 single crystals reveal extended regions of temperature T and magnetic field H for reversible flux line (FL) motion. The peak temperature ('irreversibility line') of the reciprocal quality factor 1/Q is found to be independent of frequency for 5*102<f<5*104 Hz, implying that the time scale of FL pinning is extremely T- and H-dependent. Extended regions of magnetic reversibility are therefore not restricted to high-Tc or extremely anisotropic materials, and depend upon sample orientation with respect to the applied field.
Competition between Al2O3 atomic layer etching and AlF3 atomic layer deposition using sequential exposures of trimethylaluminum and hydrogen fluoride (2017)

The thermal atomic layer etching (ALE) of Al<sub>2</sub>O<sub>3</sub> can be performed using sequential and self-limiting reactions with trimethylaluminum (TMA) and hydrogen fluoride (HF) as the reactants. The atomic layer deposition (ALD) of AlF<sub>3</sub> can also be accomplished using the same reactants. This paper examined the competition between Al<sub>2</sub>O<sub>3</sub> ALE and AlF<sub>3</sub> ALD using in situ Fourier transform infrared (FTIR) vibrational spectroscopy measurements on Al<sub>2</sub>O<sub>3</sub> ALD-coated SiO<sub>2</sub> nanoparticles. The FTIR spectra could observe an absorbance loss of the Al-O stretching vibrations during Al<sub>2</sub>O<sub>3</sub> ALE or an absorbance gain of the Al-F stretching vibrations during AlF<sub>3</sub> ALD. The transition from AlF<sub>3</sub> ALD to Al<sub>2</sub>O<sub>3</sub> ALE occurred versus reaction temperature and was also influenced by the N<sub>2</sub> or He background gas pressure. Higher temperatures and lower background gas pressures led to Al<sub>2</sub>O<sub>3</sub> ALE. Lower temperatures and higher background gas pressures led to AlF<sub>3</sub> ALD. The FTIR measurements also monitored AlCH<sub>3</sub>* and HF<sup>*</sup> species on the surface after the TMA and HF reactant exposures. The loss of AlCH<sub>3</sub>* and HF<sup>*</sup> species at higher temperatures is believed to play a vital role in the transition between AlF<sub>3</sub> ALD at lower temperatures and Al<sub>2</sub>O<sub>3</sub> ALE at higher temperatures. The change between AlF<sub>3</sub> ALD and Al<sub>2</sub>O<sub>3</sub> ALE was defined by the transition temperature. Higher transition temperatures were observed using larger N<sub>2</sub> or He background gas pressures. This correlation was associated with variations in the N<sub>2</sub> or He gas thermal conductivity versus pressure. The fluorination reaction during Al<sub>2</sub>O<sub>3</sub> ALE is very exothermic and leads to temperature rises in the SiO<sub>2</sub> nanoparticles. These temperature transients influence the Al<sub>2</sub>O<sub>3</sub> etching. The higher N<sub>2</sub> and He gas thermal conductivities are able to cool the SiO<sub>2</sub> nanoparticles more efficiently and minimize the size of the temperature rises. The competition between Al<sub>2</sub>O<sub>3</sub> ALE and AlF<sub>3</sub> ALD using TMA and HF illustrates the interplay between etching and growth and the importance of substrate temperature. Background gas pressure also plays a key role in determining the transition temperature for nanoparticle substrates.
Adaptive IRC algorithm to overcome inter-cell interference in uplink LTE system (2011)

The effect of noise can be effectively overcome using maximal ratio combining (MRC) algorithm as uplink detection algorithm without interference or in weak interference, but the performance is poor under the strong interference. And noise can be overcome by using interference rejection combining (IRC) algorithm under the strong interference, but noise can't be eliminated on condition that there is no interference. The advantages of two algorithms are combined very well in improved algorithm which is proposed in this paper. The switchover of these two algorithms is changed adaptively by judging the strength of interference. Using MRC algorithm without interference or in weak interference and using IRC algorithm in strong interference, the error rate will be reduced, thus performance of system will be improved.
61.5: LED‐Based Light‐Recycling Light Sources for Projection Displays (2006)

Abstract LED‐based light sources utilizing novel light‐recycling cavities have been developed that have small output etendue. A portion of the light emitted by the LED source is recycled back to the LEDs to enhance both the average brightness of the source and the brightness of the cavity output. Experimentally, we have achieved brightness enhancement factors of approximately 1.3x–2.0x.
Rapid and Efficient Differentiation of Rodent Neural Stem Cells into Oligodendrocyte Progenitor Cells (2019)

Oligodendrocyte progenitor cells (OPCs) may have beneficial effects in cell replacement therapy of neurodegenerative disease owing to their unique capability to differentiate into myelinogenic oligodendrocytes (OLs) in response to extrinsic signals. Therefore, it is of significance to establish an effective differentiation methodology to generate highly pure OPCs and OLs from some easily accessible stem cell sources. To achieve this goal, in this study, we present a rapid and efficient protocol for oligodendroglial lineage differentiation from mouse neural stem cells (NSCs), rat NSCs, or mouse embryonic stem cell-derived neuroepithelial stem cells. In a defined culture medium containing Smoothened Agonist, basic fibroblast growth factor, and platelet-derived growth factor-AA, OPCs could be generated from the above stem cells over a time course of 4-6 days, achieving a cell purity as high as ∼90%. In particular, these derived OPCs showed high expandability and could further differentiate into myelin basic protein-positive OLs within 3 days or alternatively into glial fibrillary acidic protein-positive astrocytes within 7 days. Furthermore, transplantation of rodent NSC-derived OPCs into injured spinal cord indicated that it is a feasible strategy to treat spinal cord injury. Our results suggest a differentiation strategy for robust production of OPCs and OLs from rodent stem cells, which could provide an abundant OPC source for spinal cord injury.
Changes in Phospholipid Composition of Erythrocyte Membrane in Alzheimer’s Disease (2012)

These changes in erythrocyte phospholipids may reflect changes induced by oxidative stress, indicating the presence of high oxidative stress in the peripheral blood of AD patients.
Towards Gene Therapy of Postoperative Adhesions: Fiber and Transcriptional Modifications Enhance Adenovirus Targeting towards Human Adhesion Cells (2013)

Postoperative abdominal/pelvic peritoneal adhesions are a major source of morbidity (bowel obstruction, infertility, ectopic gestation as well as chronic pelvic pain) in women. In this study, we screened various transduction and transcription modifications of adenovirus (Ad) to identify those that support maximal Ad-mediated gene delivery to human adhesion fibroblasts, which in turn would enhance the efficacy of this novel treatment/preventative strategy for postoperative adhesions. We transduced primary cultures of human peritoneal adhesion fibroblasts with fiber-modified Ad vectors Ad5-RGD-luc, Ad5-Sigma-luc, Ad5/3-luc and Ad5-CAV2-luc as well as transcriptional targeting viruses Ad5-survivin-luc, Ad5-heparanase-luc, Ad5-mesothelin (MSLN)-CRAd-luc and Ad5-secretory leukoprotease inhibitor (SLPI)-luc, and compared their activity to wild-type Ad5-luc. At 48 h, luciferase activity was measured and normalized to the total protein content in the cells. Among the fiber-modified Ad vectors, Ad5-Sigma-luc and among the transcriptional targeting modified Ad vectors, Ad5-MSLN-CRAd-luc showed significantly increased expression levels of luciferase activity at 5, 10 and 50 plaque forming units/cell in adhesion fibroblast cells compared with wild-type Ad5-luc (p < 0.05). Specific modifications of Ad improve their gene delivery efficiency towards human peritoneal adhesion fibroblasts. Developing a safe localized method to prevent/treat postoperative adhesion formation would have a major impact on women health.
Differences in the Incidence of Congestive Heart Failure by Ethnicity (2008)

The higher risk of incident CHF among African Americans was related to differences in the prevalence of hypertension and diabetes mellitus as well as socioeconomic status. The mechanisms of CHF also differed by ethnicity; interim myocardial infarction had the least influence among African Americans, and left ventricular mass increase had the greatest effect among Hispanic and white participants.
SYSTEMATIZATION OF CRINICAL INFORMATION AND APPLICATION OF ADVANCED INFORMATION TECHNOLOGY TO MEDICAL SAFETY (2003)

ミッションプログラム医療安全研究グループにおいては, 日々の診療で膨大に発生する各種の診療情報から, 情報処理技術の適用により医学的知見を抽出し, その知識を国内で共有化する為の汎用的な手法について研究を行っている. 研究にあたっては, 倫理面に配慮された適切な情報収集・管理手法によって得られた実際の診療情報を, 医学と工学, それぞれの専門家が共同で体系化することにより, 臨床的に有用な知見を得るにいたっている. これらの医学的成果及びその普及手段としての技術的成果を併せて報告する.
Gas Composition Support Aids for Space Vehicle Compartments Based on CO2 Hydrogenation, H2O Electrolysis, CO2 Removal and Concentration (1995)

&lt;div class="htmlview paragraph"&gt;Consideration is given to Gas Composition Support Aids (GCSA) for habitable space station based on CO&lt;sub&gt;2&lt;/sub&gt; removal and concentration, CO&lt;sub&gt;2&lt;/sub&gt; hydrogenation, water electrolysis&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;by the example of Life Support System Module (LSSM) of the International Space Station Alpha Russian Segment.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;Using Life Support System Module, for the first time an attempt was made to integrate the process of oxygen recovery from CO&lt;sub&gt;2&lt;/sub&gt; based on Sabatier reaction into a common processing cycle with the aim to use it in real flight conditions.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;The article describes the problems to be solved by means of an interaction of the above subsystems; the principles of systems and control interaction developed; the problems that arose during development of a given technological process; also mention was made of the points that are to be settled during development and conduct of tests.&lt;/div&gt;
Localization of biological sources with arrays of superconducting gradiometers (1986)

It is shown that a planar array of superconducting gradiometers with integrated dc SQUID’s fabricated with a lithographic technique is suitable in the study of biomagnetic fields. The comparisons were made between this kind of array and one made of traditional second-order gradiometers. These comparisons were made solving the inverse problem with both arrays. The localization procedure is described in the paper, considering also the effect of noise. The magnetic field generator was simulated using the simple current dipole model. Arrays of planar integrated gradiometers should permit the construction of multichannel systems for real time localization of the sources responsible for biomagnetic signals.
Ushering along B cells to neutralize HIV (2019)

Progress in staged immunizations designed to elicit a vaccine response is reported
Treatment with extracellular HSP70/HSC70 protein can reduce polyglutamine toxicity and aggregation (2005)

The accumulation of insoluble protein aggregates is a feature of neurodegenerative disease. Overexpression of Heat Shock Protein 70 (HSP70) can protect cells with protein aggregates from apoptosis. Another trait of HSP70 is its ability to cross the plasma membrane. Therefore, we purified a preparation of HSP70/HSC70 from bovine muscle and used it in a model of Huntington's disease. Human neuroblastoma SK-N-SH cells were transfected with huntington exon 1 with short (25) or long (103) CAG trinucleotide repeats coupled to green flourescent protein (GFP). Cells transfected with the long polyCAG repeat had insoluble protein aggregates and died through apoptosis. Biotinylated HSP70/HSC70 incorporated into the culture medium appeared inside the cells within 3-6 h of incubation. This incorporation correlated with a reduction in apoptotic cells by 40-50%. Confocal microscopy revealed that labelled internalized HSP70/HSC70 co-localized with the polyglutamine inclusions. The measurement of the number and size of inclusions showed that HSP70/HSC70 was able to reduce both these parameters. A filter trap assay and immunoblotting demonstrated that the introduction of HSP70/HSC70 also decreased protein aggregation. Together with earlier data on the effects of exogenously administered HSP70/HSC70 on cultured cells and on animals, these data show that preparations based on HSP70 may have some potential as therapies for a variety of neurodegenerative pathologies.
Multiobjective intelligent computer-aided design (1991)

A methodology for multiobjective intelligent computer-aided design (MICAD) of large-scale systems is proposed. The proposed MICAD methodology partitions the knowledge base required for the design system to include a progressively acquired preferential component captured using a decision theoretic model and an a priori acquired operational component that can be represented using a wide range of artificial intelligence and expert systems techniques. User preferences are employed to personalize the search for improved designs and dynamic acquisition of those preferences enables the systems, to some extent, to mimic and conform to different users, decision-making styles, and design goals. The primary emphasis is the decision theoretic treatment of user preference in a general search strategy and design domain. The construction of the operational knowledge base is demonstrated to be an opportunity for application of existing artificial intelligence techniques.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Dynamics of stiff-chain polymers in isotropic solution: zero-shear viscosity of rodlike polymers (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDynamics of stiff-chain polymers in isotropic solution: zero-shear viscosity of rodlike polymersTakahiro Sato and Akio TeramotoCite this: Macromolecules 1991, 24, 1, 193–196Publication Date (Print):January 1, 1991Publication History Published online1 May 2002Published inissue 1 January 1991https://pubs.acs.org/doi/10.1021/ma00001a030https://doi.org/10.1021/ma00001a030research-articleACS PublicationsRequest reuse permissionsArticle Views248Altmetric-Citations37LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Obesity in Schizophrenia: What can be Done About it? (2004)

Obesity is a common problem for people with schizophrenia, with an estimated 40-60% of this population being obese or overweight. Obesity among the mentally ill may contribute to adverse medical and psychological consequences as well as medication non-compliance and poorer quality and enjoyment of life. This review discusses the issues related to obesity in schizophrenia and the role of pharmacological and behavioural treatments in the reduction of obesity and maintenance of gains.
K-OPLS package: Kernel-based orthogonal projections to latent structures for prediction and interpretation in feature space (2008)

The properties of the K-OPLS method are well suited for analysis of biological data, which in conjunction with the availability of the outlined open-source package provides a comprehensive solution for kernel-based analysis in bioinformatics applications.
Photoaligning and photopatterning technology: applications in displays and photonics (2016)

The advantages of LC photoalignment technology in comparison with common “rubbing” alignment methods tend to the continuation of the research in this field. Almost all the criteria of perfect LC alignment are met in case of azo-dye layers. Nowadays azo-dye alignment materials can be already used in LCD manufacturing, e.g. for the alignment of monomers in LCP films for new generations of photonics and optics devices. Recently the new application of photoaligned technology for the tunable LC lenses with a variable focal distance was proposed. New optically rewritable (ORW) liquid crystal display and photonics devices with a light controllable structure may include LC E-paper screens, LC lenses with a variable focal distance etc. Fast ferroelectric liquid crystal devices (FLCD) are achieved through the application of nano-scale photo aligning (PA) layers in FLC cells. The novel photoaligned FLC devices may include field sequential color (FSC) FLC with a high resolution, high brightness, low power consumption and extended color gamut to be used for PCs, PDAs, switchable goggles, and new generation of switchable 2D/3D LCD TVs, as well as photonics elements.
Delivering Your Transit Message Cost Effectively (2007)

Small agencies with limited marketing budgets can use low-cost or free media to extend their message when it comes to announcing new or changed service. This article provides some suggestions for how to frame a promotion campaign and possible outlets for it. The media options are important, because different messages work better in different formats. The budget should be drawn up ahead of time to better assess which options are the most desired. Using free marketing advice such as marketing classes at local colleges or universities is one way to reduce costs. Other outreach projects like speaking engagements, events at community centers and promotions should be included in the campaign.
Densely Sulfophenylated Segmented Copoly(arylene ether sulfone) Proton Exchange Membranes (2011)

Segmented copoly(arylene ether sulfone) membranes having densely sulfonated pendent phenyl blocks were synthesized by the coupling reaction of phenoxide-terminated oligomers with bis(4-hydroxyphenyl) sulfone and decafluorobiphenyl (DFBP), followed by postpolymerization sulfonation of the blocks containing pendent phenyl substituents. The coupling reaction was conducted at relatively low temperature by utilizing highly reactive DFBP to prevent any possible trans-etherification that would randomize the hydrophilic–hydrophobic sequences. Segmented copolymer molecular weights were reasonably high, as determined by viscosity measurements. Postsulfonation occurred selectively on the pendent phenyl substituent to yield hydrophilic blocks that were highly sulfonated in regular sequence on the linked phenyl rings. The resulting polymers gave transparent, flexible, and tough membranes by solution casting. Morphological observation by transmission electron microscopy (TEM) and atomic force microscopy (AFM) showed that the high local concentration and regular sequence of pendent sulfonic acid groups within the hydrophilic blocks enhanced nanophase separation between the hydrophobic and hydrophilic blocks. A comparison of copolymers with similar ion exchange capacities (IECs) indicated that proton conductivity and water uptake were strongly influenced by the hydrophilic block sequence lengths. Proton conductivity and water uptake increased with increasing block length, even at low relative humidity (RH). The ionomer membrane with X20Y20 (X and Y refer to the number of hydrophilic and hydrophobic repeat units, respectively) and 1.82 mequiv/g of IEC had a proton conductivity of 3.6 × 10–2 S/cm at 80 °C and 50% RH, which is comparable to that of perfluorinated ionomer (Nafion) membrane (4.0 × 10–2 S/cm).
Designing adaptive middleware for reuse (2004)

Today's software component technology does not support safe deployment of real-time and multimedia applications. We propose <i>platform managed</i> deployment configuration and dynamic adaptation to enable component middleware to exploit adaptive components. An example of a remote video binding shows how alternate configurations are compared using error prediction functions to select the best for the current deployment environment.
Mechanism of formation of 4-hydroxy-5-methyl-3(2H)-furanone, a component of beef flavor, from Amadori products (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMechanism of formation of 4-hydroxy-5-methyl-3(2H)-furanone, a component of beef flavor, from Amadori productsKevin B. Hicks and Milton S. FeatherCite this: J. Agric. Food Chem. 1975, 23, 5, 957–960Publication Date (Print):May 1, 1975Publication History Published online1 May 2002Published inissue 1 May 1975https://pubs.acs.org/doi/10.1021/jf60201a005https://doi.org/10.1021/jf60201a005research-articleACS PublicationsRequest reuse permissionsArticle Views180Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts