gebhart/patrepeval huggingface dataset:
The role graph model and conflict of interest (1999)

We describe in more detail than before the reference model for role-based access control introduced by Nyanchama and Osborn, and the role-graph model with its accompanying algorithms, which is one way of implementing role-role relationships. An alternative role insertion algorithm is added, and it is shown how the role creation policies of Fernandez et al. correspond to role addition algorithms in our model. We then use our reference model to provide a taxonomy for kinds of conflict. We then go on to consider in some detail privilege-privilege and and role-role conflicts in conjunction with the role graph model. We show how role-role conflicts lead to a partitioning of the role graph into nonconflicting collections that can together be safely authorized to a given user. Finally, in an appendix, we present the role graph algorithms with additional logic to disallow roles that contain conflicting privileges.
ChemInform Abstract: New Cannabinoid‐Like Chromane and Chromene Derivatives from Rhododendron anthopogonoides. (2012)

Abstract Anthopogocyclolic acid (I) and anthopogochromenic acid (II) are isolated along with 5 related compounds which are known as synthetic analogues of cannabinoids.
Solid-state chemistry of inorganic materials VIII : symposium held November 29-December 3, Boston, Massachusetts, U.S.A. (2011)

Part I. Novel Synthetic Methods: 1. Superconducting parent compound Pr2CuO4 achieved by special post-reduction Hideki Yamamoto 2. Controlled hydrothermal synthesis of complex mixed oxides using solution redox chemistry Richard Walton 3. Building 3D materials from adjustable 2D-units towards the design of new bi-based compounds Marie Colmont Part II. Poster Session: Solid State Chemistry of Inorganic Materials VIII: 4. Growth of ruthenium and ruthenium oxide nanoplates Lamartine Meda 5. Synthesis of layered titanate micro/nano-materials for efficient pollutant treatment in aqueous media Yuxin Tang 6. Thermodynamic aspects of transition metals doped ZnO David Sedmidubsky 7. The true nature of conducting proton in perovskite ceramic membrane Aneta Slodczyk 8. Thermodynamics of oxygen chemistry on PbTiO3 and LaMnO3 (001) surfaces Ghanshyam Pilania 9. The effect of boron on processing and phosphorescence behavior of SrAl4O7 (SA2) co-doped with Eu2+ and Dy3+ Cleva Ow-Yang 10. pO2 stability of Ba0.5Sr0.5Co0.8Fe0.2O3-delta Stefan Wagner Part III. Thermoelectrics and Related Materials: 11. Thermoelectric properties of new thallium tellurides Holger Kleinke Part IV. Poster Session: Solid State Inorganic Materials Chemistry - VIII: 12. DLC-coated substrate for infrared absorption spectroscopy in supercritical water Takuji Ube 13. Two-step sintering process for lutetium oxide transparent ceramics Xiaomei Guo 14. Low temperature phase diagram of NH3BH3 Bertil Sundqvist 15. Growth and characterization of shape-controlled single crystals by a micro-pulling-down method Yuui Yokota 16. Correlation between deep-level defects and current collapses in AlGaN/GaN hetero-structures probed by steady-state photo-capacitance spectroscopy Yoshitaka Nakano 17. Deep-level characterization of free-standing HVPE-grown GaN substrates: using transparent conductive polyaniline schottky contacts Yoshitaka Nakano 18. Hydrogen atom adsorption on aluminum clusters: an electronic structures density functional study Thi Viet Bac Phung Part V. Poster Session: Solid State Inorganic Materials Chemistry VIII: 19. Synthesis and characterization of indium oxide doped hematite xIn2O3(1-x)alpha-Fe2O3 solid solution Monica Sorescu 20. Periodically ordered mesoporous Co3O4/heteropoly acid composite frameworks for catalytic applications Gerasimos Armatas 21. Preparation of protonated titanate nanotube films with an extremely large wetting contrast Yuekun Lai Part VI. Wide-Band-Gap Semiconductors and Catalytic Materials: 22. A DFT and HRTEM study of MoS2/Co: locating promoters in catalytic nanostructures Manuel Ramos Part VII. Porous Materials and Metal-Organic Frameworks: 23. Covalently interconnected and separated vanadosilicate shells Allan Jacobson.
Review of the clinical trials activity of the soft tissue and bone sarcoma group of the european organization for research and treatment of cancer (1988)

Despite the low incidence of sarcomas, the Soft Tissue and Bone Sarcoma Group has established itself as one of the more active cooperative groups of the European Organization for Research and Treatment of Cancer. Performing over a 10 yr period three phase III protocols (total entry 750 patients), three randomized phase II studies (464 patients), a pilot combination study (185 patients), and 12 phase II studies (406 patients). The new randomized phase III protocol for advanced soft-tissue sarcoma will provide an interesting test of the validity of the current membership policy, which has not discouraged the participation of enthusiastic new members. For extremity sarcomas, improved surgical techniques have increased the number of patients retaining functional limbs but have maintained excellent rates of local control. However, systemic metastasis remains a significant problem and presents a challenge for future adjuvant studies.
Pharmacokinetics of Biosynthetic and Pituitary Human Growth Hormones in Rats (1988)

The pharmacokinetics of biosynthetic and pituitary human growth hormones (B-hGH and P-hGH) was compared in rats. Normal and hypophysectomized male and female rats were subcutaneously and intramuscularly injected with 100 micrograms/kg B-hGH and P-hGH and intravenously with 60 micrograms/kg B-hGH and P-hGH. A statistically significantly smaller distribution volume and a slower metabolic clearance rate (MCR) was found for B-hGH compared to P-hGH. A statistically significantly smaller distribution volume and MCR was found for hypophysectomized rats compared to normal rats. The plasma half lives were estimated to be about 3-7 min. (alpha 1/2) and 29 min. (beta 1/2). The plasma levels of hGH were higher after subcutaneous compared to intramuscular administration. The data imply that an extensive local degradation took place at the subcutaneous and intramuscular injection sites. Comparative tissue distribution studies were performed with radioiodinated B-hGH and P-hGH. No differences were observed between the growth hormones. It was found that most of the labelled TCA precipitable material was cleared through the liver. The females cleared relatively more through the liver than the males, while the males cleared relatively more through the kidneys.
Antiplatelet Agents (2010)

Abstract In addition to their life‐sustaining role in hemostasis and wound healing, platelets play a central role in the pathogenesis of coronary artery, cerebrovascular, and peripheral vascular diseases. Under pathologic conditions such as rupture of an atherosclerotic plaque, the platelet activation mechanism and coagulation mechanism synergize in the formation of an occlusive thrombus leading to ischemic disorders such as acute coronary syndrome and stroke. Antiplatelet agents are the mainstay of pharmacological approach for the treatment of ischemic vascular disorders. Platelets have multiple cell‐surface receptors that, upon activation by specific ligands, trigger a cascade of cellular events resulting in the activation of the integrin glycoprotein (GP) IIb/IIIa receptors. Activated GP IIb/IIIa receptors cross‐link with fibrinogen causing platelet to aggregate. Aggregated platelets get trapped by fibrin meshwork, produced by the proteolysis of fibrinogen by thrombin. Cell‐surface platelet receptors have been the target of antiplatelet therapy. For example, aspirin, the most widely used antiplatelet agent, inhibit the biosynthesis of thromboxane A 2 , the endogenous agonist that activates thromboxane receptors. The ADP antagonists such as clopidogrel and ticlopidine inhibit ADP‐mediated activation of purinergic P2Y 12 receptors. Glycoprotein IIb/IIIa antagonists such as abciximab, eptifibatide, and tirofiban inhibit GP IIb/IIIa receptors, which involve the final common pathway of platelet aggregation. Phosphodiesterase inhibitors are less widely used antiplatelet agents that potentiate intracellular cyclic AMP levels. Promising newer antiplatelet agents such as thrombin receptor antagonists with reduced bleeding liability, third‐generation thienopyridine ADP antagonists with improved potency and reversible ADP antagonists are at advanced stage of development.
SEIZURE SEMIOLOGY, NEUROIMAGING PROFILE AND INTELLECTUAL OUTCOME IN CHILDREN WITH TUBEROUS SCLEROSIS COMPLEX (2006)

Objectives: To determine whether seizure prototype, interictal electroencephalograms (EEGs) and tubers burden as seen with magnetic resonance imaging (MRI) are predictive of degree of seizure control and intellectual outcome in children with tuberous sclerosis complex (TSC).
The MDR genes (1998)

P-glycoprotein is a member of a small gene family. Humans have two genes, MDR1 and MDR3, while mice and hamsters have three each, mdr1, mdr2, and mdr3 in mice and pgp1, pgp2 and pgp3 in hamsters. Of these, only MDR1 in humans, mdr1 and mdr3 (mdr1a and mdr1b) in mice and pgp1 and pgp2 in hamsters can confer the multidrug resistance phenotype (Chin et al, 1989; Ng et al., 1989).
Modeling of Failure Mechanisms Using the True Stress-Strain Response of Polymeric Foam Materials (2011)

Abstract Polymeric foams are widely used in various engineering applications. Understanding and quantitative modeling of foam load-displacement behavior is important for design and development of engineering structures with foams. In this paper we analyze three main micro-mechanisms of foam macroscopic deformation and failure using stress-true- strain diagram of loading cycle. Specifically, connection between 1) large reversible deformation and buckling, 2) large elasto-plastic deformation and 3) brittle fracture of individual cell structural elements on one side and macroscopic foam behavior on the other is discussed. Identification of specific micro-mechanism responsible for macroscopic behavior foam is suggested on the basis of detailed analysis of unloading part of stress-true strain diagram, i.e., strain recovery process.
Tricyclohexylphosphine Complexes of Ruthenium, Rhodium, and Iridium and Their Reactivity Toward Gas Molecules (1982)

Single-stage syntheses from commercially available chlorides and spectroscopic characterization are given for several tricyclohexylphosphine (PCy3) complexes of ruthenium [HRuCl(CO)(PCy3)2, Ru(CO)3(PCy3)2], rhodium [HRhCl2(PCy3)2, trans-RhCl(CO)(PCy3)2], and iridium [HIrCl2(PCy3)2, trans-IrCl(CO)(PCy3)2]. The iridium (I) precursor [IrCl(C8H14)2]2 has been used to yield HIrCl2(PCy3)2(dma) (dma = oxygen-bonded N,N'-dimethylacetamide), H2IrCl(PCy3)2, and deuterated derivatives, HIr(OH)Cl(CH3CN)(PCy3)2, IrCl(C6H5CN)-(PCy3)2, and IrCl(PCy3)2O2. Further data are presented on previously reported complexes such as containing a coordinated cyclohexenyl ring and M(COD)Cl(PCy3)(M = Rh and Ir; COD = 1,5-cyclooctadiene). The carbonyls H2IrCl(CO)-(PCy3)2 and two isomers of HIrCl2(CO)(PCy3)2 are characterized also. Attempts to isolate PCy3 complexes containing CO2 were unsuccessful.
Behaviour of prestressed bolts on overlapping friction steel connections for tubular wind towers (2014)

Behaviour of prestressed bolts on overlapping friction steel connections for tubular wind towers
Constructing a “Native” Oxyfluoride Layer on Fluoride Particles for Enhanced Upconversion Luminescence (2018)

Abstract The efficiency and tenability of upconversion fluorescence are correlated closely to the structure of host materials. Herein, an oxyfluoride layer grown in situ on fluoride‐based upconversion crystals through a high‐temperature air annealing is employed to synthesize stable lattice‐mismatch NaYF 4 :Yb 3+ /Er 3+ @YOF:Yb 3+ /Er 3+ core/shell architecture with greatly enhanced upconversion luminescence. Such a “native” oxyfluoride layer suppresses the surface quenching and modulates the phonon energy of host materials. Consequentially, the upconversion emitting intensity of NaYF 4 :Yb 3+ /Er 3+ increases over ≈25 times after covering a “native” YOF layer. The luminescence red/green ratio is manipulated from ≈1.3 to ≈11.2. By incorporating NaYF 4 :Yb 3+ /Er 3+ @YOF:Yb 3+ /Er 3+ into the TiO 2 photoanode of dye‐sensitized solar cells (DSSCs), the photon–electron conversion efficiency of DSSCs increases by ≈17.1% due to the improved near‐infrared photon harvest. This work provides a novel core/shell construction route toward high‐efficiency upconversion systems.
Multiscale, multifunction diffractive structures wet etched into fused silica for high-laser damage threshold applications (1998)

We combined functionalities of two diffractive optics with almost 100x lateral and vertical scale-length difference onto a single fused-silica surface. Fine-scale (2-mum-period) gratings for beam sampling were printed in photoresist by interference lithography and transferred to the substrate by a hydrofluoric acid etch. Subsequently, 115-mum-linewidth stairstep gratings for color separation at focus were proximity printed and wet etched in a two-mask process. Line shapes of the lamellar sampling grating are remarkably preserved following etching of the much deeper color separation grating structures with this nominally isotropic etch process. Model simulations of isotropic etching of topographical features show good agreement with the measured shape evolution of the sampling grating profiles, and the simulations reveal the sensitivity of the final feature shape to its initial aspect ratio. As a rule of thumb, lamellar grating profiles can be etched approximately 0.08A(-2) times their modulation depth, where A is their initial aspect ratio (height/width), before they evolve into a cusplike shape and begin to lose height.
Detailed characterization of gamma delta T cells within the organs in mice: classification into three groups. (1993)

gamma delta T cells are known to localize preferentially in the epithelial regions and the hepatic sinusoids, and exhibit highly restricted V gene usage depending on their location. In the present study, gamma delta T cells in mice were further characterized in terms of their expression of the interleukin-2 receptor beta-chain (IL-2R beta), CD4 and CD8, and CD8 alpha and beta. This experiment was arranged to investigate whether gamma delta T cells have different properties depending on the organs and how gamma delta T cells are different from extrathymic alpha beta T cells, i.e. alpha beta T cells in the liver and intraepithelial lymphocytes in the intestine, in terms of the above phenotypes. Three-colour immunofluorescence tests using monoclonal antibodies revealed that gamma delta T cells can be classified into three groups: gamma delta T cells of the liver type are all IL-2R beta+, are comprised of double-negative (DN) CD8-CD4- and single-positive CD8+ (no CD4+) cells, and express CD8 alpha+ beta-; gamma delta T cells of the thymus type are a mixture of IL-2R beta+ and IL-2R beta-, are mainly DN, and express CD8 alpha+ beta+ if they carry CD8 antigens; and gamma delta T cells of the intestine type are also IL-2R beta+ or IL-2R beta-, are all CD8+, and express CD8 alpha+ beta-. gamma delta T cells in the spleen of normal mice are of the thymus type, while gamma delta T cells in the spleen of athymic nude mice seem to be of the liver type. All these properties of gamma delta T cells resemble those of extrathymic alpha beta T cells rather than regular alpha beta T cells of thymic origin. The present results reveal that gamma delta T cells and other extrathymic alpha beta T cells have many properties in common as primitive lymphocytes in phylogenetic development.
Rearrangement of 1,2,4-triazin-3-ones to imidazolin-2-ones and of cinnolin-3-one to oxindole (1971)

Amination of cinnolin-3-one with hydroxylamine-O-sulphonic acid gives 2-aminocinnolin-3-one which undergoes a novel rearrangement to oxindole; similar treatment of 1,2,4-triazine-3-ones gives high yields of the analogous ring-contracted products, imidazolin-2-ones, directly.
Short Collagen Fibers Provide Control of Contraction and Permeability in Fibroblast-Seeded Collagen Gels (2004)

Tissue engineering may allow for the reconstruction of breast, facial, skin, and other soft tissue defects in the human body. Cell-seeded collagen gels are a logical choice for creating soft tissues because they are biodegradable, mimic the natural tissue, and provide a three-dimensional environment for the cells. The main drawback associated with this approach, however, is the subsequent contraction of the gel by the constituent cells, which severely reduces permeability, initiates apoptosis, and precludes control of the resulting shape and size of the construct. In this study, type I collagen gels were seeded with fibroblasts and cast either with or without the addition of short collagen fibers. Gel contraction was monitored and permeability was assessed after 7 and 14 days in culture. The addition of short collagen fibers both significantly limited contraction and increased permeability of fibroblast-seeded collagen gels. The addition of short collagen fibers had no detrimental effect on cell proliferation, and there were a high number of viable fibroblasts in gels with fibers and gels without fibers. Gels containing short collagen fibers demonstrated permeabilities that were 100 to 1000 times greater than controls and also closely maintained their casting dimensions (never less than 96% of original). By limiting contraction and maintaining permeability, the incorporation of short collagen fibers should enable the creation of larger constructs by allowing for greater nutrient diffusion, and permit the creation of more complicated shapes during gel casting.
Short Note: Linearization of the eikonal equation (1994)

Abstract Seismic traveltime tomography is a nonlinear inverse problem wherein an unknown slowness model is inferred from the observed arrival times of seismic waves. Nonlinearity arises because the raypath connecting a given source and receiver depends on the slowness. Specifically, if L(s) designates a raypath through the slowness model s between two fixed endpoints, then the path integral for traveltime t(s)=∫L(s)s dl is a nonlinear functional of s because it does not, in general, satisfy the superposition condition (i.e., t(s1, + s2) ≠ t(s1), + t(s2) where s1 and s2 are two different slowness models). The tomographic inverse problem can be solved after linearizing the traveltime expression about a known slowness model s0. This linearized expression is usually obtained by appealing to Fermat's principle (e.g., Nolet, 1987). Alternately, the required relation can be rigorously derived via ray-perturbation theory (Snieder and Sambridge, 1992). The purpose of this note is to present a straightforward derivation of the same result by linearizing the eikonal equation for traveltimes. Wenzel (1988) adopts this approach, but his method of proof cannot be generalized to heterogeneous 3-D media. A full 3-D treatment is given here. The proof is remarkably simple, and thus it is quite possible that others have discovered it previously.
On the reported attempts to radically improve the performance of the steam methane reforming reactor (1996)

Abstract Steam reforming of light hydrocarbons is a key step for producing hydrogen and syngas for important processes in the petroleum and petrochemical industries. Since the establishment of the SMR process in 1930, research and development have led to improved catalyst performance and improved reactor tube materials. Since about 1970, new reactor configurations have been considered. The authors critically review recent attempts to radically improve the SMR reactor performance, analyze the areas of improvement and the suitability of proposed configurations for different reforming applications.
Exercise-induced electrocardiographic changes after treadmill exercise testing in healthy children: A comprehensive study (2021)

Diastolic time decreased more than systolic time with exercise and systolic time to diastolic time increased with exercise. Hodges' and Fridericia's formulas resulted in the longest and shortest QT and QoT, JT, and JTP, respectively. Thus, using a single value as the cut-off for long QT syndrome can lead to under or over-diagnosis. Nomograms incorporating data on age, heart rate, and heart rate correction formula are indispensable for accurate long QT diagnosis. Furthermore, gender differences in ventricular repolarization parameters are not generally present in 5 to 14-year-old healthy children. The lack of U wave in this study may implicate the need for more careful investigation in the presence of U wave in the treadmill exercise testing of healthy children.
Genetics in Sjögren's syndrome: where we are and where we go. (2019)

Sjögren's syndrome is a complex autoimmune disease that involves dysregulation of immune responses that preferentially target exocrine glands. Systemic manifestations vary and may involve nearly every organ system. Genetic studies to date are in their infancy relative to other autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis, each with more than 100 genetic associations now established. However, recent work in SS has successfully established associations that shed light on pathophysiology and implicate aberrant innate and adaptive immune responses. In this review, we provide an overview of genetic approaches used to identify risk variants in SS, discuss major findings and their relevance to SS, and describe the future directions that are likely to lead to understanding fundamental causes of this disease and new opportunities for improving clinical care.
Nanotubes de Carbone : Systèmes pour la limitation optique (2004)

Annick Loiseau, Président du Jury<br />François Hache, Rapporteur<br />Serge Lefrant, Rapporteur<br />Richard Hollins, Examinateur<br />Didier Riehl, Examinateur<br />Eric Anglaret, Directeur de thèse
Effect of Polyvinyl Alcohol Ligands on Supported Gold Nano-Catalysts: Morphological and Kinetics Studies (2021)

The effect of polyvinyl alcohol (PVA) stabilizers and gold nanoparticles supported on active carbon (AuNPs/AC) was investigated in this article. Polymers with different molecular weights and hydrolysis degrees have been synthesized and used, like the stabilizing agent of Au nano-catalysts obtained by the sol-immobilization method. The reduction of 4-nitrophenol with NaBH<sub>4</sub> has been used as a model reaction to investigate the catalytic activity of synthesized Au/AC catalysts. In addition, we report several characterization techniques such as ultraviolet-visible spectroscopy (UV-Vis), dynamic light scattering (DLS), X-ray diffraction (XRD), transmission electron microscopy (TEM), and X-ray photoelectron spectroscopy (XPS) in order to correlate the properties of the polymer with the metal nanoparticle size and the catalytic activity. A volcano plot was observed linking the catalytic performance with hydrolysis degree and the maximum of the curve was identified at a value of 60%. The Au:PVA-60 weight ratio was changed in order to explain how the amount of the polymer can influence catalytic properties. The effect of nitroaromatic ring substituents on the catalytic mechanism was examined by the Hammett theory. Moreover, the reusability of the catalyst was investigated, with little to no decrease in activity observed over five catalytic cycles. Morphological and kinetic studies reported in this paper reveal the effect of the PVA polymeric stabilizer properties on the size and catalytic activity of supported gold nanoparticles.