gebhart/patrepeval huggingface dataset:
Patient-specific electro-anatomical modeling of cochlear implants using deep neural networks (2022)

Cochlear implants (CIs) are considered the standard-of-care treatment for profound sensory-based hearing loss. After CI surgery, an audiologist will adjust the CI processor settings for CI recipients to improve overall hearing performance. However, this programming procedure can be long and may lead to suboptimal outcomes due to the lack of objective information. In previous research, our group has developed methods that use patient-specific electrical characteristics to simulate the activation pattern of auditory nerves when they are stimulated by CI electrodes. However, estimating those electrical characteristics require extensive computation time and resources. In this paper, we proposed a deep-learning-based method to coarsely estimate the patient-specific electrical characteristics using a cycle-consistent network architecture. These estimates can then be further optimized using a limited range conventional searching strategy. Our network is trained with a dataset generated by solving physics-based models. The results show that our proposed method can generate high-quality predictions that can be used in the patient-specific model and largely improves the speed of constructing models.
Editorial Nanosensors for Defense and Security (2008)

The 59 articles in this special issue focus on nanosensors for defense and security.
Clinical impact of laparoscopic surgery and adhesion prevention material for prevention of small bowel obstruction (2022)

Laparoscopic surgery helps to reduce SBO incidence only in colorectal surgery, and possibly in gastroduodenal surgery. APM does not reduce SBO after abdominal surgery.
Moves towards Authentic Freedom. Church and State in Switzerland, and Beyond (2015)

Many of the Swiss Cantons have regulated the relations between church and state by establishing, in their public law, corporations at the levels of the municipality and of the canton. The role and the rights of these corporations, especially obligatory membership in them, is the object of ongoing political and legal debate. Both on the side of the courts and of the church, the present system has come under scrutiny, while the corporation representatives and also a majority of the population seem intent on maintaining it. This paper explains and examines the presently valid church-state relations, focusing on the Canton of Zurich, and looks at the suggestions for reform elaborated by an experts’ commission instituted by the Conference of Swiss Bishops. In conclusion, it presents some more general reflections on the challenges to individual and corporative religious freedom today, in Switzerland and beyond.
Understanding the Effect of DISI Injector Deposits on Vehicle Performance (2012)

&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;Combustion in direct injection spark ignition (DISI) engines is strongly influenced by the in-cylinder charge motion. The charge motion depends both on the injection strategy as well as the geometry of the combustion chamber/air intake system and the physical location of the injectors (side mounted vs. centrally mounted).&lt;/div&gt;&lt;div class="htmlview paragraph"&gt;For boosted and downsized DISI engines, many manufacturers are favouring a single late injection or a split injection strategy. This has the advantage of creating high levels of turbulence which leads to faster combustion and improved thermodynamic efficiency. Furthermore the charge cooling offers enhanced knock resistance, thereby allowing more spark advance. The calibration of such engines is critical: the prize of greater thermodynamic efficiency must be balanced against the risks of charge inhomogeneity, namely excessive particulate emissions and poor drivability.&lt;/div&gt;&lt;div class="htmlview paragraph"&gt;A bench mounted four cylinder turbo DISI was operated with a fuel designed to promote injector fouling. After making the injectors dirty under normal driving conditions, a progressive increase in injection duration was observed, combined with deterioration in combustion efficiency. Normal operation using a fuel with detergent additive was found to be able to restore the performance of the engine.&lt;/div&gt;&lt;/div&gt;
Reconstructing ancestral gene content by coevolution (2009)

Inferring the gene content of ancestral genomes is a fundamental challenge in molecular evolution. Due to the statistical nature of this problem, ancestral genomes inferred by the maximum likelihood (ML) or the maximum-parsimony (MP) methods are prone to considerable error rates. In general, these errors are difficult to abolish by using longer genomic sequences or by analyzing more taxa. This study describes a new approach for improving ancestral genome reconstruction, the ancestral coevolver (ACE), which utilizes coevolutionary information to improve the accuracy of such reconstructions over previous approaches. The principal idea is to reduce the potentially large solution space by choosing a single optimal (or near optimal) solution that is in accord with the coevolutionary relationships between protein families. Simulation experiments, both on artificial and real biological data, show that ACE yields a marked decrease in error rate compared with ML or MP. Applied to a large data set (95 organisms, 4873 protein families, and 10,000 coevolutionary relationships), some of the ancestral genomes reconstructed by ACE were remarkably different in their gene content from those reconstructed by ML or MP alone (more than 10% in some nodes). These reconstructions, while having almost similar likelihood/parsimony scores as those obtained with ML/MP, had markedly higher concordance with the coevolutionary information. Specifically, when ACE was implemented to improve the results of ML, it added a large number of proteins to those encoded by LUCA (last universal common ancestor), most of them ribosomal proteins and components of the F(0)F(1)-type ATP synthase/ATPases, complexes that are vital in most living organisms. Our analysis suggests that LUCA appears to have been bacterial-like and had a genome size similar to the genome sizes of many extant organisms.
Incidence of tonsillar cancer in northern Sweden: Impact of human papilloma virus (2015)

The incidence rate of tonsillar cancer is increasing worldwide. The current study identifies a parallel increase in the incidence of tonsillar cancer, human papilloma virus (HPV) and p16 expression among a population from northern Sweden, a sparsely populated area, confirming the strong association between p16 and HPV infection in tonsillar tissue. Data from the Swedish Cancer Registry was assessed to identify cases of tonsillar cancer in the northern territorial area of Sweden. HPV DNA was extracted from paraffin embedded diagnostic biopsies and detected by polymerase chain reaction using general primers Gp5+/6+ and CpI/IIG. Expression of p16 was identified by immunochemistry. Patients were grouped into urban or rural residence categories. A total of 214 cases were identified, comprising 155 (72.4%) men and 59 (27.6%) women, and 65 of these patients, who presented between 2000 and 2012, were analyzed. The overall median age for the analyzed patients was 58 years; 48 (74%) were males (median age, 57.5 years) and 17 (26%) were females (median age, 65 years). Of the 65 specimens, 59 (91%) were positive for HPV, and 62 (95%) expressed p16. The incidence of tonsillar cancer in the cohort demonstrated a 2-fold increase between 1990 and 2013; specifically, a 2.7-fold increase was observed in men whilst the female group exhibited only a small increase. These findings demonstrate a strong association between p16 expression and HPV infection in tonsillar malignancies. The incidence of HPV-positive tonsillar cancer has increased in recent years, even in sparsely populated regions, as demonstrated in northern Sweden.
Comparison of Lateral Resolution of Fine Stripes Beryllium and Boron Implanted by Focused Ion Beam in Si-Doped AlGaAs/GaAs Multiquantum Wells (1987)

Using impurity controlled Al–Ga intermixing in Si-doped Multi-Quantum Wells (MQW), a highly anisotropic Be diffusion after Focused Ion Beam (FIB) implantation and thermal annealing was measured by Auger Al profiles analysis, with a Be lateral diffusion dependent on the scan speed of ion beam. Then, after the demonstration of Al–Ga intermixing suppression by Boron FIB implantation, an improved lateral pattern resolution was obtained with Boron implantation in Si-doped MQW.
PKI based Encryption for Document Sharing, Optimized Storage, and Proof of Existence in the Cloud (2015)

PKI based Encryption for Document Sharing, Optimized Storage, and Proof of Existence in the Cloud
The NRPB radon personal dosimetry service (1988)

A radon personal dosemeter has been developed. The dosemeter is simple, cheap, robust, disposable and indelibly numbered. The operation principle is that of a radon diffusion chamber, which principle has been established both experimentally and theoretically. The dosemeter is an enclosure which excludes radon progeny and detritus whilst allowing access of radon gas. The alpha particles from the decay of radon gas, and from radon progeny, which are, in the main, plated out on the detector and on the dosemeter walls, are registered in a piece of poly allyl diglycol carbonate (PADC). The number of alpha particle tracks recorded is proportional to the time integral of the radon gas concentration external to the dosemeter. Since December 1986, NRPB has been offering a dosimetry service approved by the appropriate UK authorities.
An efficient extension of the zero-crossing technique to measure frequency of noisy signals (2012)

The paper contains a proposal for the estimation of the frequency of a sine signal corrupted by zero-mean additive white gaussian noise. The method resorts to the histogram of the time intervals between adjacent zero-crossing samples. Validation has been carried out for various noise levels and results show that the relative error is much less than other algorithms for frequency estimation. Performances are also compared to those of numeric counters. The method can be easily implemented of low cost devices and is computationally very efficient.
Templating Assembly of Multifunctional Hybrid Colloidal Spheres (Adv. Mater. 20/2012) (2012)

3D hybrid colloidal spheres with integrated functions and collective properties are fabricated by X. Yan, Y. Li, and co-workers on page 2663 using a variety of common, inorganic nano-objects as building blocks in association with polyelectrolyte encapsulation through a facile template strategy. This simple and controllable strategy is suited to the design and fabrication of functional colloidal spheres, thereby allowing the development of new multifunctional hybrid materials.
Mitochondrial DNA cytochrome b gene variation reveals different largemouth bass genealogies (1996)

A mitochondrial DNA character set based on cytochrome b gene variations is described that may be used in conjunction with established nuclear gene differences to assess largemouth bass Micropterus salmoides population structure and dynamics. Alignment of known cytochrome b sequences revealed two regions where the functional constraints of the molecule appear to be sufficiently reduced to allow several amino acid substitutions. Restriction analysis was used to probe nucleotide variation within one of these evolutionary hotspots, resulting in the discovery of fixed largemouth bass subspecific cytochrome b haplotypes. Application of two molecular character sets, one founded on fixed allelic variation in nuclear genes and the other on mtDNA cytochrome b diversity, revealed that in several Texas populations, where the Florida subspecies was introduced into extant populations of northern largemouth bass, hybridization was evident. The direction of the introgression vector could be determined through the combination of both character Sets.
Supplementary Table S1. from Target Identification in Small Cell Lung Cancer via Integrated Phenotypic Screening and Activity-Based Protein Profiling (2023)

&lt;p&gt;Cell viability screen in SCLC cells against Roche published kinase inhibitor set&lt;/p&gt;
Development of a 3D Printed, Bioengineered Placenta Model to Evaluate the Role of Trophoblast Migration in Preeclampsia (2016)

Preeclampsia (PE) is a leading cause of maternal and perinatal morbidity and mortality. Current research suggests that the impaired trophoblastic invasion of maternal spiral arteries contributes significantly to the development of PE. However, the pathobiology of PE remains poorly understood, and there is a lack of treatment options largely due to ineffective experimental models. Utilizing the capability of bioprinting and shear wave elastography, we developed a 3D, bioengineered placenta model (BPM) to study and quantify cell migration. Through BPM, we evaluated the effect of epidermal growth factor (EGF) on the migratory behavior of trophoblast and human mesenchymal stem cells. Our results demonstrate a positive correlation between cell migration rates and EGF concentration. These results indicate that a feasible <i>ex vivo</i> placental model can be bioprinted to examine cellular, molecular, and pharmacologic interactions. In addition, EGF clearly affects the celluar migration, a potential therapeutic agent to treat preeclampsia. We envision that our <i>ex vivo</i> tissue modeling approach can be readily transferred to study other normal biologic and abnormal pathologic processes such as fibroblast migration in wound healing and stem cell homing.
Field emission properties of nano-layered carbon lateral edge emitters (2011)

Summary form only given. In this presentation, field emission properties of nano layered carbon (NLC) lateral edge emitters will be presented. During this study, the diamond like carbon films were fabricated with pulse laser deposition process using a 1.8 joule Q-switched Nd:YAG laser. The number of nano layers was varied from 4 to 16. The thickness was varied from 2.5nm to 10nm. These NLC emitter layers were patterned into triode edge emitters using standard photolithography process and their field emission properties were studied under high vacuum conditions. Identical emitters were fabricated on substrates of different thermal conductivities to study the thermal heating effects. Under optimum conditions, single tip currents as high as 200 micro-amps have been measured.
The Springboard: How Storytelling Ignites Action in Knowledge-Era Organizations (2000)

Preface Sighting the Springboard Story Telling a Story that Rings True Communicating a Vision Getting Inside an Idea A Tale of Two Stories Co-Creating the Same Story Another Mode of Knowing Crafting the Springboard Story Performing the Springboard Story Building Up the Springboard Story Embodying the Idea in a Story The Medusa's Stare Appendices Bibliography
The synthesis of the epoxide and some other possible metabolites of precocene I (1984)

The synthesis of precocene I epoxide, 3,4-epoxy-7-methoxy-2,2-dimethylchroman (8), is described. This compound is the highly reactive metabolite responsible for the biological effects of the precocenes. The syntheses of some other oxygenated derivatives of precocene I, which are themselves possible metabolites, are also described.
Preface (1985)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text Anthony J. Devaney, "Preface," J. Opt. Soc. Am. A 2, 1902-1903 (1985) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
ACS Applied Engineering Materials: A New Journal for Applied Materials Research (2022)

ADVERTISEMENT RETURN TO ISSUEEditorialNEXTACS Applied Engineering Materials: A New Journal for Applied Materials ResearchJessica D. Schiffman*Jessica D. SchiffmanDepartment of Chemical Engineering, University of Massachusetts Amherst, Amherst, Massachusetts 01003-9303, United States*Email: [email protected]More by Jessica D. Schiffmanhttps://orcid.org/0000-0002-1265-5392Cite this: ACS Appl. Eng. Mater. 2023, 1, 1, 1–2Publication Date (Web):September 15, 2022Publication History Received2 September 2022Published online15 September 2022Published inissue 27 January 2023https://pubs.acs.org/doi/10.1021/acsaenm.2c00098https://doi.org/10.1021/acsaenm.2c00098editorialACS PublicationsCopyright © 2022 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views11444Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (4 MB) Get e-AlertscloseSUBJECTS:Biomaterials,Interfaces,Macromolecules,Materials,Materials science Get e-Alerts
NMR Metabolome-Based Classification of Cymbopogon Species: a Prospect for Phyto-equivalency of its Different Accessions Using Chemometric Tools (2022)

Abstract Cymbopogon species are widely distributed worldwide and known for their high essential oil content with potential commercial and medicinal benefits justifying for their inclusion in food and cosmetics. Most species received scant characterization regarding their full complement of bioactive constituents necessary to explain their medicinal activities. In this study, the metabolite profiles of 5 Cymbopogon species, C . citratus , C . flexuosus , C . procerus , C . martini , and C . nardus , were characterized via NMR-based metabolomics. The results of 13 shoot accessions revealed the identification and quantification of 23 primary and secondary metabolites belonging to various compound classes. Multivariate analyses were used for species classification, though found not successful in discrimination based on geographical origin. Nevertheless, C . citratus was found particularly enriched in neral, geranial, ( E )-aconitic acid, isoorientin, and caffeic acid as the major characterizing metabolites compared to other species, while an unknown apigenin derivative appeared to discriminate C . martini . The high essential oil and phenolic content in C . citratus emphasizes its strong antioxidant activity, whereas ( E )-aconitic acid accounts for its traditional use as insecticide. This study affords the first insight into metabolite compositional differences among Cymbopogon species. Moreover, antimicrobial, insecticidal, antidiabetic, and antioxidant compounds were identified that can be utilized as biomarkers for species authentication.
Micro Jet Engine Oil Consumption Measurement Technique (2009)

Oil consumption of micro gas turbine engines plays a significant role with regards to their practical application in aerospace. In this context an oil consumption measurement device has been developed on behalf of Daimler AG for the application to vehicle turbo chargers. This device has been used to measure the oil consumption of an own design micro jet engine of 400 N thrust. The design of the device is based on the principle of gravimetric weighting. In the past, volumetric principles have been applied to engine oil consumption measurements. Technical advances in the field of piezoelectricity have improved the accuracy of gravimetric weighting in such a way that today its accuracy is comparable to volumetric gauging. Moreover, unlike volumetric gauging gravimetric weighting is not influenced by the density or the amount of emulsified gas in the oil. Hence, application of gravimetric weighting represents a more robust and more efficient way to evaluate oil consumption in micro gas turbine engines. Unlike non-conventional measurement strategies like emission measurement and tracer techniques, gravimetric weighting allows very simple and convenient oil consumption measurements [3]. The device was validated using defined laboratory measurements. Experimental results are shown.
Block Matching Algorithm based on RANSAC Algorithm (2010)

A new type of real-time image stabilization system is introduced in present paper. RANSAC Algorithm is used in the system. The accuracy and speed of image stabilization is improved effectively. A low-cost and high-performance solution of real-time digital image stabilization system is given in this paper. Video stabilization working principle is discussed and the moving image mathematical model is set up. The RANSAC Algorithm can reduce the amount of calculation and the error rate of block matching. Simulation of the real-time image stabilization system is accomplished. The result shows the new model is effective; the power SNR of the video is raised about 8–10dB.
Phoneme recognition in continuous speech (2005)

An algorithm for phoneme recognition in continuous speech is presented. A continuous matching process is employed to bypass the segmentation problem. A large set of standard patterns is used to solve the allophonic variation problem. Also, a hierarchical recognition algorithm is proposed to realize feasible matching in a real time. In the first stage of the hierarchical recognition algorithm, vowels in speech are spotted. To optimize accuracy in vowel spotting, each standard pattern is carefully selected, constraints on the "phoneme chain" of continuous speech are utilized, and partial standard pattern matching is employed for detailed phoneme analysis. The second stage recognizes consonants between vowels. Experimental results show a 91% vowel recognition rate and 80% consonant recognition rate for a specified speaker.
Shape bottlenecks and conservative flow systems [medical image analysis] (1996)

Proposes an alternative to mathematical morphology to analyze complex shapes. This approach aims mainly at the detection of shape bottlenecks which are often of interest in medical imaging because of their anatomical meaning. The detection idea consists in simulating the steady state of an information transmission process between two parts of a complex object in order to highlight bottlenecks as areas of high information flow. This information transmission process is supposed to have a conservative flow which leads to the well-known Dirichlet-Neumann problem. This problem is solved using finite differences, over-relaxation and a raw to fine implementation. The method is applied to the detection of main bottlenecks of brain white matter network, namely corpus callosum, anterior commissure and brain stem.