gebhart/patrepeval huggingface dataset:
Interference Coordination in Multiple Antenna Based LTE-Advanced Heterogeneous Systems (2013)

With picocells deployed in the coverage of a macrocell in heterogeneous networks (HetNets), the macrocell evolved NodeB (MeNB) may receive interference signals from the picocell users, which results in more severe co-channel interference (CCI) problem in the uplink. In this paper, the spatial uplink interference coordination is investigated in multiple antenna systems, according to which the receiver coding matrix is generated by MeNB to mitigate the CCI from picocell users. Two interference coordination (IC) schemes are proposed based on whether the receiver coding matrix is full rank or not, named as full coding (IC-FC) and part coding (IC-PC), respectively. The application of the proposed schemes is discussed in single picocell and multiple picocell scenarios. The CCI can be totally canceled in single picocell scenario, and an algorithm is developed in multiple picocell networks to mitigate the most severely interfering picocell. Link level and system level simulations are applied, and it is shown that significant performance gain is achieved by our proposed schemes over traditional IC receivers.
2-, 3-, and 4-(.alpha.,.alpha.,.beta.,.beta.-Tetrafluorophenethyl)benzylamines. A new class of antiarrhythmic agents (1977)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT2-, 3-, and 4-(.alpha.,.alpha.,.beta.,.beta.-Tetrafluorophenethyl)benzylamines. A new class of antiarrhythmic agentsMarcia E. Christy, C. Dylion Colton, Mary Mackay, William H. Staas, Julia B. Wong, Edward L. Engelhardt, Mary L. Torchiana, and Clement A. StoneCite this: J. Med. Chem. 1977, 20, 3, 421–430Publication Date (Print):March 1, 1977Publication History Published online1 May 2002Published inissue 1 March 1977https://pubs.acs.org/doi/10.1021/jm00213a021https://doi.org/10.1021/jm00213a021research-articleACS PublicationsRequest reuse permissionsArticle Views354Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
THE IMPACT OF PRENATAL DIAGNOSIS ON THE LONG-TERM OUTCOME OF CHILDREN WITH CONGENITAL HEART DISEASE (2005)

Purpose: Congenital heart defects represent one of the major causes of infant morbidity and mortality. Intrauterine identification of congenital heart defects allows optimal postnatal management of the neonates including delivery in a tertiary centre permitting immediate early interventions. However the impact of prenatal diagnosis on the long-term outcome of these infants is still under debate.
Two-photon tomography using on-chip quantum walks (2016)

We present an approach to quantum tomography based on first expanding a quantum state across extra degrees of freedom and then exploiting the introduced sparsity to perform reconstruction. We formulate its application to photonic circuits and show that measured spatial photon correlations at the output of a specially tailored discrete-continuous quantum walk can enable full reconstruction of any two-photon spatially entangled and mixed state at the input. This approach does not require any tunable elements, so it is well suited for integration with on-chip superconducting photon detectors.
Impact of Massively Parallel Computation on Protein Structure Determination (2020)

For the past two decades, an important paradigm in protein chemistry has been the assertion that a biologically active protein is at thermodynamic equilibrium and therefore adopts its minimum free energy structure. Although some evidence now suggests that not all proteins conform to this notion, it is true often enough to remain an important guiding principle in structure determination, whether by direct computation or by the computationally assisted approaches of diffraction and resonance. Among the difficulties in predicting structure from sequence are the lack of a useful potential function incorporating the influence of solvent and the inability to sample the phase space efficiently or even to determine whether a free energy minimum is, in fact, the global minimum. These problems are general. Although they are greatly mitigated by experimental information, they become increasingly severe as empirical constraints are reduced. We review the difficulties involved in the general problem of protein structure prediction and discuss the impact of increased computer power in the context of new approaches to solvation and parallel algorithm design. A general focus of our discussion is the need to understand the theoretical basis for effective theories and to accommodate in numerical methods the interplay of different temporal and spatial scales.
On Physical Adsorption (1955)

Calculations of the energies of interaction between a gas and a solid surface have hitherto not been definitively compared with experimental results, because of difficulty in evaluating the contributions that make up the measured heat of adsorption. Methods described in previous papers provide a means of analyzing experimental data in terms of the adsorptive potential of the gas with respect to the most frequent patch of the surface. The adsorptive potential thus obtained is made up of the dispersion interactions plus an energy term due to interaction between the dipole of the adsorbate and the electric field of the substrate. For the inert gases adsorbed by graphite enough information is now available for calculation of the necessary quantities. The results derived from experiment are compared with calculations of the dispersion energies using potential functions of different degrees of approximation. Crowell's approximation of the lattice sum, in which the graphite lattice is treated as a set of planes of continuous structure and uniform density, when applied to a 6-8-10-12 potential function, is found to correspond most closely to the observed values.
The Role of Cortical Modularity in Tactile Information Processing: An Approach to Measuring Information Processing Deficits in Autism (2013)

The Role of Cortical Modularity in Tactile Information Processing: An Approach to Measuring Information Processing Deficits in Autism
The fused multiply-add instruction leads to algorithms for extended-precision floating point: applications to java and high-performance computing (1999)

Portability in Java requires that all architectures produce the same result for a particular floating-point calculation. Conceptually, the best defnition for this result is the correctly rounded value of the infinitely precise result. Although this is likely an unattainable goal in general, it should be striven for when attainable with reasonable performance. Although many architectures implement IEEE double-precision arithmetic in hardware, providing the correctly rounded result for the basic operations (+,-,*,/) with good performance, most do not provide hardware support for extended precison arithmetic. The performance and accuracy of the resulting software implementations can be poor.Many machines provide a double-precision fused multiply-add (FMA) instruction that computes d = a * b + c with d correctly rounded. Using the FMA instruction, higher performance algorithms for extended-precision arithmetic can be divised. We present examples of such algorithms for the basic operations, +,-,*,/. The algorithms always compute the exact result for each of the operations. This contributes to the Java goal of portability by providing a large Spectrum of architectures on which it is possible to efficiently implement correctly rounded extended precision floating point. The FMA is also valuable in large-scale computation of linear algebra problems, where the accumulation of dot products is a basic operation. Performing this accumulation in extended precision greatly increases the size of problem that may be solved before roundoff error becomes a limiting factor. It also produces a much faster way, over just using IEEE arithmetic, of doing the more accurate computation.Given two integers a and b, there exist unique integers q and r such that a = bq + r with 0 ≤ r < b. In number theory, this lemma is the computational basis for proving the Fundamental Theorem of Arithmetic.Note that a = bq + r has the same form as the FMA. The exact nature of the FMA and this lemma allow us to define multiplication and division of IEEE numbers exactly. Furthermore, the FMA instruction provides a much faster way to perform these exact computations. Thus, we will demonstrate a clear need for Java to accept the FMA as a standard instruction.Finally, we demonstrate the accuracy of the algorithms on example problems (matrix multiplication, 2 × 2 determinant, complex multiplication, and triangle area calculation), for which existing computer arithmetic gives completely inaccurate results in certain instances.
HyperGCN: A New Method For Training Graph Convolutional Networks on Hypergraphs (2019)

In many real-world networks such as co-authorship, co-citation, etc., relationships are complex and go beyond pairwise associations. Hypergraphs provide a flexible and natural modeling tool to model such complex relationships. The obvious existence of such complex relationships in many real-world networks naturally motivates the problem of learning with hypergraphs. A popular learning paradigm is hypergraph-based semi-supervised learning (SSL) where the goal is to assign labels to initially unlabelled vertices in a hypergraph. Motivated by the fact that a graph convolutional network (GCN) has been effective for graph-based SSL, we propose HyperGCN, a novel way of training a GCN for SSL on hypergraphs based on tools from sepctral theory of hypergraphs. We demonstrate HyperGCN's effectiveness through detailed experimentation on real-world hypergraphs for SSL and combinatorial optimisation and analyse when it is going to be more effective than state-of-the art baselines. We have made the source code available.
Pain reducing effect of three types of transcutaneous electrical nerve stimulation in patients with chronic pain: a randomized crossover trial (2004)

Transcutaneous electrical nerve stimulation (TENS) is a frequently applied therapy in chronic pain although evidence for effectiveness is inconclusive. Several types of TENS, based on different combinations of frequency, pulse duration and intensity, exist. The precise mechanism of action and the relevance of combinations of stimulus parameters are still unclear. To compare the effectiveness of three types of TENS we conducted a randomized, single blinded crossover trial. Patients received two times a 2-week period of daily TENS treatment, separated by a washout period of 2 weeks. In total, 180 chronic pain patients were randomized into three groups. In group 1, high frequency, low intensity TENS (HFT) was compared with high frequency, high intensity TENS (HIT). In groups 2 and 3, HFT and HIT were compared with a control TENS (COT). The order of applying the different modalities of TENS in each group was also randomized. Primary outcome was the patient's overall assessment of effectiveness and pain reduction (VAS). No differences were found in patient's assessment or pain reducing effect between the three groups, indicating no superiority of one type of TENS. In total, 56% continued TENS after the 2-week treatment period. At 6 months, 42% of all patients still used TENS. We concluded that there were no differences in effectiveness for the three types of TENS used in this study. Because no placebo group was included, no definite conclusions on effectiveness of TENS in general in the treatment of chronic pain could be made.
One-step construction of unsymmetrical thioureas and oxazolidinethiones from amines and carbon disulfide via a cascade reaction sequence (2019)

A concise and versatile method for the construction of unsymmetrical thioureas and oxazolidinethiones from amines and carbon disulfide has been achieved in DMSO without addition of extra reagents. The present protocol is compatible with various secondary amines and primary amines, and suitable for intermolecular and intramolecular reactions. Diverse unsymmetrical thioureas and oxazolidinethiones were efficiently obtained in good to excellent yields <i>via</i> a cascade reaction sequence.
The evolution of care improves outcome in blunt thoracic aortic injury: A Western Trauma Association multicenter study (2017)

Therapeutic/care management, level III.
Synthesis and Ligand-Based Mixed Valency ofcis-andtrans-CrIII(X4SQ)(X4Cat)(L)n(X = Cl and Br,n= 1 or 2) Complexes:  Effects of Solvent Media on Intramolecular Charge Distribution and Ligand Dissociation of CrIII(X4SQ)3 (2002)

The treatment of Cr(III)(X(4)SQ)(3) (SQ = o-semiquinonate; X = Cl and Br) with acetonitrile affords trans-Cr(III)(X(4)SQ)(X(4)Cat)(CH(3)CN)(2) (X = Cl (1) and Br (2)). In the presence of 2,2'-bipyridine (bpy) or 3,4,7,8-tetramethyl-1,10-phenanthrene (tmphen), the reaction affords Cr(III)(X(4)SQ)(X(4)Cat)(bpy).nCH(3)CN (X = Cl, n = 1 (3); X = Br, n = 0.5 (4)) or Cr(III)(X(4)SQ)(X(4)Cat)(tmphen) (X = Cl (5) and Br (6)), respectively. All of the complexes show a ligand-based mixed-valence (LBMV) state with SQ and Cat ligands. The LBMV state was confirmed by the presence of the interligand intervalence charge-transfer band. Spectroscopic studies in several solvent media demonstrate that the ligand dissociation included in the conversion of Cr(III)(X(4)SQ)(3) to 1-6 occurs only in solvents with relatively high polarity. On the basis of these results, the effects of solvent media were examined and an equilibrium, Cr(III)(X(4)SQ)(3) <--> Cr(III)(X(4)BQ)(X(4)SQ)(X(4)Cat) (BQ = o-benzoquinone), is proposed by assuming an interligand electron transfer induced by solvent polarity.
Conditional Depletion of Airway Progenitor Cells Induces Peribronchiolar Fibrosis (2010)

Colocalization of proliferation and cell type-specific markers demonstrate that Clara cells are critical airway progenitor cells. Continuous depletion of Clara cells resulted in persistent squamous metaplasia, lack of normal reepithelialization, and peribronchiolar fibrosis. Induction of proliferation in subepithelial fibroblasts supports the concept that chronic epithelial depletion caused peribronchiolar fibrosis.
Formulation of an Aqueous Titania Suspension and its Patterning with Ink‐Jet Printing Technology (2011)

We present a general protocol for processing cost‐beneficial, environmentally benign aqueous‐type suspensions containing metal‐oxide nanostructured particles, and their patterning with piezoelectric ink‐jet printing technology. The critical issues relevant to ink‐jet printing are the preparation and stabilization of nanosized particles in a fluid and adjusting its physical properties to the values appropriate for a particular ink‐jet printer mechanism. We discuss and illustrate, on a model titania system, the processing of a highly stable, colloidal, water‐based suspension containing particles not bigger than 570 nm, prepared by a ball‐milling process. For the ink‐jet printing experiments, the surface tension and the viscosity of the suspension were modified by the addition of a small amount of the appropriate non‐ionic amphiphiles and glycerol. The formation of droplets, their positioning on the substrate, and the shape and uniformity of the dots on the substrate are discussed and correlated with the fluid properties via the inverse Ohnesorge number Z . It was shown successfully that uniform, regular‐shaped TiO 2 dots with a diameter of 30 μm and a good positioning accuracy on Si/SiO 2 substrates could be obtained by jetting a fluid with Z values of 5 and 9 using a piezoelectric ink‐jet printer with a nozzle diameter of 21 μm operating at an amplitude of 13 V and a frequency of 5 kHz.
Fault-Tolerant Routing Mechanism in 3D Optical Network-on-Chip Based on Node Reuse (2019)

The three-dimensional Network-on-Chips (3D NoCs) has become a mature multi-core interconnection architecture in recent years. However, the traditional electrical lines have very limited bandwidth and high energy consumption, making the photonic interconnection promising for future 3D Optical NoCs (ONoCs). Since existing solutions cannot well guarantee the fault-tolerant ability of 3D ONoCs, in this paper, we propose a reliable optical router (OR) structure which sacrifices less redundancy to obtain more restore paths. Moreover, by using our fault-tolerant routing algorithm, the restore path can be found inside the disabled OR under the deadlock-free condition, i.e., fault-node reuse. Experimental results show that the proposed approach outperforms the previous related works by maximum 81.1 percent and 33.0 percent on average for throughput performance under different synthetic and real traffic patterns. It can improve the system average optical signal to noise ratio (OSNR) performance by maximum 26.92 percent and 12.57 percent on average, and it can improve the average energy consumption performance by 0.3 percent to 15.2 percent under different topology types/sizes, failure rates, OR structures, and payload packet sizes.
Measurement of power supply noise tolerance of self-timed processor (2009)

We have compared the power supply noise tolerance of a synchronous processor and a self-timed processor fabricated using 0.18mum CMOS. We have designed the self-timed processor using the same RTL as the synchronous processor, and translated it into a netlist with DCVSL circuits and completion logic trees. We have demonstrated the synchronous processor shows an error rate of 9.3% for the worst power supply noise in case of 10% timing margin design. On the other hand, the self-timed processor shows 40% speed degradation, but no error, for the same power supply noise.
Antenna switching based on the relation between the relative location of array elements for high resolution 2-D DOA estimation (2014)

This paper presents a method of synthesizing covariance matrix elements of array input signal based on the relation between the relative location of array elements for high resolution 2-D Direction-Of-Arrival (DOA) estimation. Antenna array generally has the same number of array elements and receiver modules which often leads large receiver hardware cost. The authors have already studied a way of antenna switching to reduce receiver cost based on the relation between the absolute location of array elements, but the receiver cost is still large and needs to be further reduced. In this paper, we propose a method of DOA estimation from sparse data by synthesizing array covariance matrix elements, via antenna switching based on the relation between the relative location of array elements. Performance of the proposed approach is evaluated in detail through computer simulation.
Abstract 4420: Small-molecule inhibition of Wee1 kinase by AZD1775 selectively sensitizes human papilloma virus (HPV)-associated cervical cancer to DNA-damaging therapies (2019)

Abstract Objective: Wee1 regulate G2-M checkpoint of cell-cycle Inhibition of Wee1 promotes cell mitosis without DNA repair in cases with TP53 deficiency Since human papillomavirus (HPV) E6 involves the inactivation of p53, we aimed to evaluate effects of Wee1 inhibitor on cervical cancer. Material and Methods: Expression level of Wee1 in cervical cancer was evaluated using Oncomine Cervical cancer cell lines, Caski (HPV16+), SiHa (HPV16+) and C33A (HPV-, P53 mut) and LNCap (HPV-, P53 wt, prostate cancer) were used. After exposure to either Wee1 inhibitor (AZD1775), cisplatin, or both, cell surviving rate was evaluated by MTT assay and expression levels of Wee1 and cell cycle related proteins were evaluated by western blotting cell cycle status in cell lines were observed by flow cytometry. Results: High expression of Wee1 in cervical cancer was clinically observed among ten cancer species. Stepwise treatment of AZD1775 promoted significant cell death induction, compared with exposure to cisplatin alone in HPV-positive cells (Caski and Siha); however no effect on cell death in HPV-negative cells (C33A and LNCap). In addition, expression level of pCDC2 was reduced after exposure to AZD1775, indicating induction of cell mitosis without DNA repair. Conclusion: Our results indicate the therapeutic potential of cervical cancer treatment by Wee1 inhibition. Synergistic effect of Wee1 inhibition with conventional treatments (CCRT or chemotherapy) may be a new strategy to improve the prognosis in cervical cancer. Citation Format: Osamu Kobayashi, Yuji Ikeda, Yuki Okuma, Nobuki Hayashi, Takahiro Nakajima, Mikiko Asai-Sato, Kei Kawana. Small-molecule inhibition of Wee1 kinase by AZD1775 selectively sensitizes human papilloma virus (HPV)-associated cervical cancer to DNA-damaging therapies [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 4420.