gebhart/patrepeval huggingface dataset:
Active CO2 reservoir management for sustainable geothermal energy extraction and reduced leakage (2013)

Abstract Subsurface storage space is gaining recognition as a commodity for industrial and energy recovery operations. Geologic carbon dioxide (CO 2 ) sequestration (GCS), wherein supercritical CO 2 is injected into subsurface storage space, is under broad development in sedimentary reservoirs – particularly for hydrocarbon production, which uses supercritical CO 2 as part of a carbon capture utilization and sequestration (CCUS) scheme. A novel CCUS operation is presented whereby we investigate the staged deployment of a coupled geothermal energy extraction (GEE)‐GCS operation in geothermal sedimentary reservoirs that re‐circulates extracted fluids. We identify sedimentary resources of the continental USA that have significant temperature at depths suitable for GCS. To predict the impact of a GEE‐GCS operation, a reservoir‐scale semi‐analytical model is used to simulate brine and CO 2 migration through existing leakage pathways. With the goal of integrating GEE and GCS, a well‐site design exercise is undertaken, where we develop an idealized configuration for CO 2 and brine production/reinjection wells. Results show potential geothermal sedimentary reservoirs suitable for GEE deployment exist in the continental USA; however the characteristics of each site should be investigated through a first stage GEE‐operation to determine GCS capacity. Our active CO 2 reservoir management simulations demonstrate a decrease in injection and reservoir overpressures, a reduced migration of CO 2 within the reservoir during active injection/extraction, and a reduced risk of brine and CO 2 migration. With the use of the developed concentric‐ring well pattern, we demonstrate the longevity of thermal productivity from an ideal GEE site, while providing sufficient CO 2 storage volume and trapping to act as a sequestration operation. © 2013 Society of Chemical Industry and John Wiley &amp; Sons, Ltd
Reaction-diffusion model for pattern formation inE. coliswarming colonies with slime (2005)

A new experimental colonial pattern and pattern transition observed in E. coli MG1655 swarming cells grown on semisolid agar are described. We present a reaction-diffusion model that, taking into account the slime generated by these cells and its influence on the bacterial differentiation and motion, reproduces the pattern and successfully predicts the observed changes when the colonial collective motility is limited. In spite of having small nonhyperflagellated swarming cells, under these experimental conditions E. coli MG1655 can very rapidly colonize a surface, with a low branching rate, thanks to a strong fluid production and a locally incremented density of motile, lubricating cells.
One-dimensional comparison of Wiener filtering and Richardson-Lucy methods for sectioned restoration of space-variant digital images (2002)

One-dimensional sections of digital images with space-variant blurs from an uncorrected optical system are restored using Wiener filtering and the Richardson-Lucy method. The simulated blur is from a single-lens optical system configured at moderate focal-length-to-aperture ratio (f#) and near-infinite conjugate. The sections are taken over a range of field-angle displacements from on-axis to approximately 15-deg off-axis. The results identify a range of field angles over which Wiener filtering is useful for sectioned restoration of blurred images from an optical system with significant point-spread-function space-variance. The results also establish a field angle range over which an iterative restoration method such as Richardson-Lucy would be necessary to accommodate point-spread-function space-variance.
Past Rifampicin Dosing Determines Rifabutin Resistance of Helicobacter pylori (2009)

Although RFB might be a potential candidate component of a new H. pylori eradication regimen following the first- or second-line failure, it should be used after examining a past history of RFP treatment.
Novel flat-panel display made of amorphous SiN:H/SiC:H thin-film LED (1993)

A novel flat-panel display made of hydrogenated amorphous silicon nitride and silicon carbide Thin Film LED (TFLED) has been developed. The a-SiN:H and a-SiC:H were prepared by a glow discharge plasma CVD technique. The emission colors can be obtained from red, yellow, green to white-blue. The amorphous TFLED can be fabricated as a large area on any foreign substrate. Any emission pattern can be obtained by designing the pattern of the internal thin film electrodes. A series of technical data on the preparation of the a-SiN:H/a-S:C:H TFLED is presented. Some new ideas of the utilizations of the developed TFLED in optoelectronic functional devices are presented and described.
Quaternary structure of influenza virus hemagglutinin after acid treatment (1986)

Hemagglutinin (HA), a trimeric spike glycoprotein of influenza virus, mediates fusion between the viral envelope and the membrane of an endosome during virus entry. Fusion is triggered by low pH, which induces an irreversible conformational change in the protein. Several studies have indicated that intersubunit contacts along the trimer interfaces may be broken during this alteration. To determine whether HA dissociates into individual subunits as a consequence of the conformational change, we used velocity gradient sedimentation in the presence of Triton X-100. We also determined the resistance of acid-treated HA to dissociation by sodium dodecyl sulfate, a property of the HA trimer. At pH 7.0, isolated HA sedimented as a 9S trimer and gave the characteristic trimer pattern after sodium dodecyl sulfate-polyacrylamide gel electrophoresis. After acidification the HA remained trimeric irrespective of whether it was exposed to acid in intact virus particles or in solubilized form. Only when very low concentrations of HA were acidified did a fraction dissociate to dimers and monomers. In contrast, the water-soluble ectodomain fragment of HA (BHA) readily dissociated under a variety of conditions. Negative-stain electron microscopy supported the notion that HA molecules in virus particles do not dissociate upon acidification and may form larger oligomeric structures in the plane of the viral membrane. Taken together, the results suggested that it is the trimeric HA, or higher-order structures thereof, that are active in the acid-induced fusion reaction. Further, the results emphasized the role of the transmembrane anchors of HA in preventing dissociation of the trimer.
Apoptosis Occurs via the Ceramide Recycling Pathway in Human HaCaT Keratinocytes (2006)

Keratinocytes contain abundant ceramides compared to other cells. However, studies on these cells have mainly focused on the barrier function of ceramide, while their other roles, such as those in apoptosis or cell cycle arrest, have not been well addressed. In this study, we investigated the apoptosis-inducing effect of exogenously added cell-permeable ceramides in HaCaT keratinocytes. We found that N-hexanoyl sphingosine (C6-ceramide) induced apoptosis efficiently through the accumulation of long chain ceramides. On the other hand, N-acetyl sphingosine (C2-ceramide) induced neither apoptosis nor accumulation of long chain ceramides. We also found that exogenously added C6-ceramide was hydrolyzed to sphingosine and then reacylated in long chain ceramides (ceramide recycling pathway), but that C2-ceramide was not hydrolyzed and thus not recycled. We propose that this is the basis for the chain length-specific heterogeneity observed in ceramide-induced apoptosis in these cells. These results also imply that keratinocytes utilize exogenous sphingolipids or ceramides to coordinate their own ceramide compositions.
Resonance energy transfer between fluorescent BSA protected Au nanoclusters and organic fluorophores (2013)

Bovine serum albumin (BSA) protected nanoclusters (Au and Ag) represent a group of nanomaterials that holds great promise in biophysical applications due to their unique fluorescence properties and lack of toxicity. These metal nanoclusters have utility in a variety of disciplines including catalysis, biosensing, photonics, imaging and molecular electronics. However, they suffer from several disadvantages such as low fluorescence quantum efficiency (typically near 6%) and broad emission spectrum (540 nm to 800 nm). We describe an approach to enhance the apparent brightness of BSA Au clusters by linking them with a high extinction donor organic dye pacific blue (PB). In this conjugate PB acts as a donor to BSA Au clusters and enhances its brightness by resonance energy transfer (RET). We found that the emission of BSA Au clusters can be enhanced by a magnitude of two-fold by resonance energy transfer (RET) from the high extinction donor PB, and BSA Au clusters can act as an acceptor to nanosecond lifetime organic dyes. By pumping the BSA Au clusters using a high extinction donor, one can increase the effective brightness of less bright fluorophores like BSA Au clusters. Moreover, we prepared another conjugate of BSA Au clusters with the near infrared (NIR) dye Dylight 750 (Dy750), where BSA Au clusters act as a donor to Dy750. We observed that BSA Au clusters can function as a donor, showing 46% transfer efficiency to the NIR dye Dy750 with a long lifetime component in the acceptor decay through RET. Such RET-based probes can be used to prevent the problems of a broad emission spectrum associated with the BSA Au clusters. Moreover, transferring energy from BSA Au clusters to Dy750 will result in a RET probe with a narrow emission spectrum and long lifetime component which can be utilized in imaging applications.
A Recursive Approach to Partially Blind Calibration of a Pollution Sensor Network (2019)

Distributed, low-cost sensor networks have become a widely used tool to aid in the interpolation of atmospheric measurements between regulatory grade monitoring stations, referred to as Golden Standards (GS). However, the quality of the data from these sensor networks can be questioned, especially in poorly correlated environments. Sensors can be individually calibrated in a laboratory environment before deployment of the network, but this approach is unfeasible for large networks. To overcome these shortcomings, we propose a novel online, autonomous approach to sensor calibration, by leveraging the ground truth measurements of the GS to calibrate neighboring nodes of the sensor network using a Recursive Least-Squares technique. Our algorithm percolates this calibration through the network such that every connected node will converge towards its ideal linear calibration. The algorithm outperforms a pre-deployment laboratory calibration and provides good tracking of quickly-changing environmental stimulus, which is known to change the inherent sensor calibration. Experimental results show a 45% improvement in estimated measurement error when compared to measurements corrected using a laboratory calibration.
Prostaglandins and Prostaglandin Intermediates. XVII [1]. Synthesis of the Main Metabolite of the PGF2α Analogue Cloprostenol (1986)

Abstract The δ‐lactone 5 , the main metabolite of the PGF 2α analogue cloprostenol, is prepared in four steps from the homologous γ‐lactone 1 in an overall yield of 42% by conversion into the γ‐lactol 3 , which is olefinated with diethyl 1‐cyano‐1‐dimethylamino‐methylphosphonate to the cyano enamine 4 and finally hydrolyzed under various conditions. The described reaction sequence represents an example for the general possibility of the ring enlargement of γ‐lactones to δ‐lactones.
Shortening Osteotomy for Treatment of Metacarpophalangeal Joint Deformity (2002)

The results of a new subcapital shortening osteotomy for correction of metacarpophalangeal joint deformity in patients with rheumatoid arthritis of the hands are presented. Seven patients (16 joints) were followed up for a mean of 33.5 months. The mean shortening of the metacarpal bone was 4.6 mm (range, 4-8 mm), and seven joints had additional intrinsic release. Only four (25%) joints held the correction of the deformity; all other joints had recurrence of palmar subluxation with or without additional ulnar drift. The range of motion of the joints with preserved correction after surgery was 80 degrees compared with 28 degrees of the joints with recurrent deformity. The possible mechanism of failure was analyzed. The results of the current series suggest that subcapital shortening osteotomy may not be indicated for treatment of severe metacarpophalangeal joint deformity in patients with rheumatoid arthritis.
OIL SPILL SORBENTS: TESTING PROTOCOL AND CERTIFICATION LISTING PROGRAM (1993)

ABSTRACT Environment Canada's Emergencies Engineering Division is spearheading a program in conjunction with the Canadian General Standards Board that would see the development of a certification and listing program in addition to a national standard for the testing of sorbent materials. Funding for this program is provided by Environment Canada (EC), Canadian Coast Guard (CCG), Marine Spill Response Corporation (MSRC), U.S. Coast Guard (USCG), and U.S. Minerals Management Service (MMS). The test methods are based upon those defined by the American Society for Testing and Materials and previous test methods developed by Environment Canada for our series of reports entitled Selection Criteria and Laboratory Evaluation of Oil Spill Sorbents. This series, which was started in 1975, encompasses a number of commercially available oil spill sorbents tested with different petroleum products and hydrocarbon solvents. The testing program will categorize the sorbents according to their operating characteristics. The main categories are oil spills on water, oil spills on land, and industrial use. The characteristics we will be evaluating with the new test protocols include initial and maximum sorption capacities, water pickup, buoyancy, reuse potential, retention profile, disintegration (material integrity), and ease of application and retrieval. In the near future we plan to incorporate changes to the test that would involve increasing our list of test liquids to encompass spills in an industrial setting, in addition to testing sorbent booms and addressing the disposal problem.
The Safety of Amphotericin B Lipid Complex in Patients With Prior Severe Intolerance to Liposomal Amphotericin B (2012)

The tolerability of amphotericin B lipid complex in patients with previous severe infusion reactions to liposomal amphotericin B is unclear. We reviewed the charts of 40 such patients at a tertiary care cancer center and found that amphotericin B lipid complex administration was uneventful in 34 patients (85% [95% confidence interval, 69%-93%]).
Candidate gene analysis of watermelon stripe pattern locus ClSP ongoing recombination suppression (2021)

Abstract Stripe pattern is an important commodity trait in watermelon, displaying diverse types. In this study, two segregating populations were generated for genetic mapping the single dominant locus ClSP , which was finally delimited to a 611.78 Kb interval with suppression of recombination. According to polymorphism sites detected among genotypes, four discrete haploblocks were characterized in this target region. Based on reference genomes, 81 predicted genes were annotated in the ClSP interval, including seven transcription factors namely as candidate No1-No7. Meanwhile, the ortholog gene of cucumber ist responsible for the irregular stripes was considered as candidate No8. Strikingly, gene structures of No1-No5 completely varied from their reference descriptions and subsequently re-annotated. Notably, the adjacent distribution candidates No2 and No3, as well as No4 and No5, were confirmed to derive from longer transcripts designated as No2_3 and No4_5, respectively. Sequence analysis demonstrated the third polymorphism in CDS of re-annotated No4_5 resulting in truncated proteins in non-stripe plants. Furthermore, only No4_5 was down-regulated in non-stripes relative to stripes contrast to other candidates. Transcriptome analysis identified 356 DEGs between striped and non-striped peels, with genes involved in photosynthesis and chloroplast development down-regulated in non-stripes but calcium ion binding related genes up-regulated. Additionally, 38 DEGs were annotated as transcription factors, with the majority up-regulated in non-stripes, such as ERFs and WRKYs. This study not only contributes to a better understanding of the molecular mechanisms underlying watermelon stripe development, but also provides new insight into the genomic structure of ClSP locus and valuable candidates.
Kriz olgularında aile içinde yaşanan şiddet (1997)

Özet: Aile içindeki şiddetin daha çok kadınlara yönelik olduğu hem yapılan çalışmalarda hem de klinik uygulamalarda gözlenmektedir.Çalışmalarda şiddeti uygulayan ve şiddete maruz kalanların be lirli bir takım özelliklere sahip oldukları da belirtil
Dual roles for the trimeric G protein Go in asymmetric cell division in Drosophila (2006)

During asymmetric division, a cell polarizes and differentially distributes components to its opposite ends. The subsequent division differentially segregates the two component pools to the daughters, which thereby inherit different developmental directives. In Drosophila sensory organ precursor cells, the localization of Numb protein to the cell's anterior cortex is a key patterning event and is achieved by the combined action of many proteins, including Pins, which itself is localized anteriorly. Here, a role is described for the trimeric G protein Go in the anterior localization of Numb and daughter cell fate specification. Go is shown to interact with Pins. In addition to a role in recruiting Numb to an asymmetric location in the cell's cortex, Go transduces a signal from the Frizzled receptor that directs the position in which the complex forms. Thus, Go likely integrates the signaling that directs the formation of the complex with the signaling that directs where the complex forms.
The genetic basis of antibody production: The dominant anti‐arsonate idiotype response of the strain a mouse (1982)

Immunization of the A strain of mice with the hapten p-azophenylarsonate (Ars) results in an immune response in which approximately 50% of the anti-Ars antibodies share cross-reactive idiotypic determinants (IdCR). A gene or genes linked to the heavy chain constant region locus is required for the production of this idiotype. The expressed VH gene from a hybridoma cell line which expresses the IdCR has been cloned. DNA hybridization studies utilizing the VH gene have revealed that there are many related genes in both idiotype-producing and idiotype-nonproducing strains of mice. However, under stringent hybridization conditions, only a single band of 6.4 kb is present in Eco R1-digested A strain DNA. Strains of mice which are phenotypically idiotype-negative either lack this band completely or possess a much weaker one at this position. Utilizing DNA from Igh recombinant strains of mice, it has been shown that the VH locus controlling idiotype expression contains the structural gene information for the idiotype-positive heavy chains. It has also been shown that DNA at this locus appears to be sufficient for the production of the cross-reactive idiotype. Utilizing a DNA probe derived from regions flanking the structural gene has confirmed the relatedness of V genes in a variety of mouse strains and revealed a significant degree of polymorphism at the Igh locus.
Program Committee Members (2007)

In this paper we consider incomplete data sets, i.e., data sets with missing attribute values. Two different types of missing attribute values are studied: lost and do not care. Furthermore, three definitions of approximations are discussed: singleton, subset, and concept. Theoretically, singleton approximations should not be used in data mining since concepts approximated by singleton approximations are not definable. However, we conducted a number of experiments on 44 different incomplete data sets using all three approximation definitions and our results show that none of these approximations is superior to the other.
The Medial Axis of a Union of Balls. (2000)

We present an algorithm for computing the exact interior medial axis of a union of balls in IR d . Our algorithm combines the simple characterization of this medial axis given by Attali and Montanvert with the combinatorial information provided by Edelsbrunner&amp;apos;s -shape. This leads to a very simple algorithm, which we implement in IR 3 . 1 Introduction There is considerable interest, in mesh generation, computer graphics, computer vision and medical imaging, in describing the shape of an object by its medial axis. But computing the medial axis of a three-dimensional object is dicult in general; it can be done for simple polyhedra using exact arithmetic and computational algebra [4]. Attali and Montanvert [1] showed that, in contrast, the medial axis of a three-dimensional union of balls has a simple structure. A union of balls, as the name suggests, is the union U of a set of balls B = fB 1 ; B 2 : : : Bn g in IR d . This is an important special case, since any three-dimension...
Nuclear material detection techniques (2008)

Illicit nuclear materials represent a threat for the safety of the American citizens, and the detection and interdiction of a nuclear weapon is a national problem that has not been yet solved. Alleviating this threat represents an enormous challenge to current detection methods that have to be substantially improved to identify and discriminate threatening from benign incidents. Rugged, low-power and less-expensive radiation detectors and imagers are needed for large-scale wireless deployment. Detecting the gamma rays emitted by nuclear and fissionable materials, particularly special nuclear materials (SNM), is the most convenient way to identify and locate them. While there are detectors that have the necessary sensitivity, none are suitable to meet the present need, primarily because of the high occurrence of false alarms. The exploitation of neutron signatures represents a promising solution to detecting illicit nuclear materials. This work presents the development of several detector configurations such as a mobile active interrogation system based on a compact RF-Plasma neutron generator developed at LBNL and a fast neutron telescope that uses plastic scintillating-fibers developed at the University of New Hampshire. A human-portable improved Solid-State Neutron Detector (SSND) intended to replace pressurized <sup>3</sup>He-tubes will be also presented. The SSND uses an ultra-compact CMOS-SSPM (Solid-State Photomultiplier) detector, developed at Radiation Monitoring devices Inc., coupled to a neutron sensitive scintillator. The detector is very fast and can provide time and spectroscopy information over a wide energy range including fast neutrons.
Time-resolved X-ray diffraction at NERL (2001)

For ultrafast material analyses, we constructed the time-resolved X-ray diffraction system utilizing ultrashort X-rays from laser-produced plasma generated by the 12-TW–50-fs laser at the Nuclear Engineering Research Laboratory. Ultrafast transient changes in laser-irradiated GaAs crystals were observed as X-ray diffraction patterns. Experimental results were compared with numerical analyses.
Abstract 16096: Snf1-Related Kinase Inhibits Cell Proliferation Through Upregulated Calcyclin Binding Protein and Reduced Beta-Catenin Signaling (2011)

Introduction: Snf1-related kinase (SNRK) is a mammalian serine-threonine kinase with sequence similarity to the AMP-activated kinase alpha subunit. SNRK localizes to the cytoplasm and nucleus, howe...