gebhart/patrepeval huggingface dataset:
In vivo photoacoustic imaging of major blood vessels in the pancreas and liver during surgery (2019)

Abdominal surgeries carry considerable risk of gastrointestinal and intra-abdominal hemorrhage, which could possibly cause patient death. Photoacoustic imaging is one solution to overcome this challenge by providing visualization of major blood vessels during surgery. We investigate the feasibility of in vivo blood vessel visualization for photoacoustic-guided liver and pancreas surgeries. In vivo photoacoustic imaging of major blood vessels in these two abdominal organs was successfully achieved after a laparotomy was performed on two swine. Three-dimensional photoacoustic imaging with a robot-controlled ultrasound (US) probe and color Doppler imaging were used to confirm vessel locations. Blood vessels in the in vivo liver were visualized with energies of 20 to 40 mJ, resulting in 10 to 15 dB vessel contrast. Similarly, an energy of 36 mJ was sufficient to visualize vessels in the pancreas with up to 17.3 dB contrast. We observed that photoacoustic signals were more focused when the light source encountered a major vessel in the liver. This observation can be used to distinguish major blood vessels in the image plane from the more diffuse signals associated with smaller blood vessels in the surrounding tissue. A postsurgery histopathological analysis was performed on resected pancreatic and liver tissues to explore possible laser-related damage. Results are generally promising for photoacoustic-guided abdominal surgery when the US probe is fixed and the light source is used to interrogate the surgical workspace. These findings are additionally applicable to other procedures that may benefit from photoacoustic-guided interventional imaging of the liver and pancreas (e.g., biopsy and guidance of radiofrequency ablation lesions in the liver).
Investigation of lactic acid bacterial strains for meat fermentation and the product's antioxidant and angiotensin‐I‐converting‐enzyme inhibitory activities (2016)

In the lactic acid bacteria (LAB) strains screened from our LAB collection, Lactobacillus (L.) sakei strain no. 23 and L. curvatus strain no. 28 degraded meat protein and tolerated salt and nitrite in vitro. Fermented sausages inoculated strains no. 23 and no. 28 showed not only favorable increases in viable LAB counts and reduced pH, but also the degradation of meat protein. The sausages fermented with these strains showed significantly higher antioxidant activity than those without LAB or fermented by each LAB type strain. Angiotensin-I-converting-enzyme (ACE) inhibitory activity was also significantly higher in the sausages fermented with strain no. 23 than in those fermented with the type strain. Higher ACE inhibitory activity was also observed in the sausages fermented with strain no. 28, but did not differ significantly from those with the type strain. An analysis of the proteolysis and degradation products formed by each LAB in sausages suggested that those bioactivities yielded fermentation products such as peptides. Therefore, LAB starters that can adequately ferment meat, such as strains no. 23 and no. 28, should contribute to the production of bioactive compounds in meat products.
Progress on the development and introduction of isdn in the linea ut (2005)

The technical solutionsfor theprogressive introduction ofthe ISDM ca pabilifies in die LINEA UT switching system are pre sented. Thepresent implementation conforms to the requirements of the Italian Initial ISDN Service, promoted by SIP; this first JS,DN release constitutes an important milestone for the further developments required by the large scale ISDN deployment of the subsequent commercial diffusion. The LINEA UT evolution through the commercialup to the matureISDNphaseis envisaged preserving the already installed exchanges.
SEA TRIALS OF THE ONE-HUNDRED-TON OIL RECOVERY VESSEL FOR BANTRY BAY (1978)

The vessel Bay Skimmer has an oa length of 68 ft, a displacement of 100 tons, and a total HP of 500. It utilizes the dynamic inclined plane principle for oil collection, harvests oil up to 3 knots, and has a top speed of 8-10 knots. The paper presents the results of builder's trials and sea trials, and the scaling of oil recovery performance for two oil recovery ships of 500 and 750 tons displacement. General arrangements are given. Order from NSFI as No. 17118.
Improved Voltage and Cycling for Li+ Intercalation in High‐Capacity Disordered Oxyfluoride Cathodes (2015)

<b>New high-capacity intercalation cathodes</b> of Li<sub>2</sub>V <i><sub>x</sub></i> Cr<sub>1-<i>x</i></sub> O<sub>2</sub>F with a stable disordered rock salt host framework allow a high operating voltage up to 3.5 V, good rate performance (960 Wh kg<sup>-1</sup> at ≈1 C), and cycling stability.
End-stage differentiation of neutrophil granulocytes in vivo is accompanied by up-regulation of p27kip1 and down-regulation of CDK2, CDK4, and CDK6 (2003)

The in vivo expression profiles of cell-cycle proteins regulating G1-to-S-phase transition were determined in three neutrophil precursor populations from human bone marrow: myeloblasts (MBs) and promyelocytes (PMs); myelocytes (MCs) and metamyelocytes (MMs); and band cells (BCs) and segmented neutrophil cells (SCs) and in mature polymorphonuclear neutrophils (PMNs) from peripheral blood. Complete cell-cycle arrest was observed in BCs/SCs and PMNs. Cyclins D1, D2, and D3 were found to be down-regulated during granulopoiesis, whereas a slight increase of cyclin E was seen. In contrast, cyclin-dependent kinase (CDK)2, -4, and -6 were down-regulated from the MC/MM stages and onward. The transcript levels of CDK2, -4, and -6 were concurrently down-regulated. As the only CDK inhibitor, p27kip1 protein and mRNA expression were up-regulated in MCs/MMs and reached peak levels in PMNs. Protein expression of retinoblastoma protein and the related pocket proteins p107 and p130 was down-regulated from the MC/MM stages and onward. This is the first report to describe expression levels of cell-cycle proteins during granulopoiesis in vivo, and it strongly contrasts the observations made in cell-culture systems in vitro.
Role of Dendritic Cell Targeting in Venezuelan Equine Encephalitis Virus Pathogenesis (2020)

The initial steps of Venezuelan equine encephalitis virus (VEE) spread from inoculation in the skin to the draining lymph node have been characterized. By using green fluorescent protein and immunocytochemistry, dendritic cells in the draining lymph node were determined to be the primary target of VEE infection in the first 48 h following inoculation. VEE viral replicon particles, which can undergo only one round of infection, identified Langerhans cells to be the initial set of cells infected by VEE directly following inoculation. These cells are resident dendritic cells in the skin, which migrate to the draining lymph node following activation. A point mutation in the E2 glycoprotein gene of VEE that renders the virus avirulent and compromises its ability to spread beyond the draining lymph blocked the appearance of virally infected dendritic cells in the lymph node in vivo. A second-site suppressor mutation that restores viral spread to lymphoid tissues and partially restore virulence likewise restored the ability of VEE to infect dendritic cells in vivo.
Cyanuric Chloride Derivatives. II. Substituted Melamines (1951)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCyanuric Chloride Derivatives. II. Substituted MelaminesDonald W. Kaiser, Jack T. Thurston, James R. Dudley, Frederic C. Schaefer, Ingenuin Hechenbleikner, and Dagfrid Holm-HansenCite this: J. Am. Chem. Soc. 1951, 73, 7, 2984–2986Publication Date (Print):July 1, 1951Publication History Published online1 May 2002Published inissue 1 July 1951https://pubs.acs.org/doi/10.1021/ja01151a002https://doi.org/10.1021/ja01151a002research-articleACS PublicationsRequest reuse permissionsArticle Views1996Altmetric-Citations78LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Task‐related changes in degree centrality and local coherence of the posterior cingulate cortex after major cardiac surgery in older adults (2017)

Cardiac surgery patients showed postoperative increases in working memory load-associated degree centrality and local coherence of the dPCC that were inversely associated with postoperative global cognitive outcomes and independent of perioperative cerebrovascular damage.
Magnetic Coil Suppression of Extrafoveal Visual Perception Using Disappearance Targets (1996)

We used magnetic brain stimulation with a butterfly coil over the occipital lobes to study extrafoveal visual field effects in six subjects. The visual test pattern was a grid of asterisks around a central fixation point, and the target was the disappearance of one asterisk for a single frame of the video monitor. Using single magnetic pulses at stimulator outputs of 55-95%, we noted robust interference effects at latencies < or = 100 ms, peaking at approximately 50-90 ms. Suppression of visual perception occurred with both transverse and sagittal alignments of the coil. When the coil was moved laterally over either occipital lobe, perception of target disappearance was consistently suppressed in the contralateral visual field. Movement of the coil rostrally produced consistent suppression in the lower and middle field, but preferential suppression of the upper field could not be obtained. This altitudinal asymmetry may be correlated with the anatomy of the occipital lobe in relation to the scalp surface.
Separation of timescales in a two-layered network (2012)

We investigate a computer network consisting of two layers occurring in, for example, application servers. The first layer incorporates the arrival of jobs at a network of multi-server nodes, which we model as a many-server Jackson network. At the second layer, active servers at these nodes act now as customers who are served by a common CPU. Our main result shows a separation of time scales in heavy traffic: the main source of randomness occurs at the (aggregate) CPU layer; the interactions between different types of nodes at the other layer is shown to converge to a fixed point at a faster time scale; this also yields a state-space collapse property. Apart from these fundamental insights, we also obtain an explicit approximation for the joint law of the number of jobs in the system, which is provably accurate for heavily loaded systems and performs numerically well for moderately loaded systems. The obtained results for the model under consideration can be applied to thread-pool dimensioning in application servers, while the technique seems applicable to other layered systems too.
Optics in 2013 (2013)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text Robert D. Guenther, Nicholas J. Frigo, Dmitry Dylov, Carlos López-Mariscal, Alessandro Restelli, Yanina Shevchenko, and Zuleykhan Tomova, "Optics in 2013," Optics & Photonics News 24(12), 24-25 (2013) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
A Multi-agent System to Manage Workflows. (2002)

The aim of this study was to estimate genetic parameters for growth traits in Mexican Nellore cattle. A univariate animal model was used to estimate (co)variance components and genetic parameters. The traits evaluated were birth weight (BW), weaning weight (WW), and yearling weight (YW). Models used included the fixed effects of contemporary groups (herd, sex, year, and season of birth) and age of dam (linear and quadratic) as a covariate. They also included the animal, dam, and residual as random effects. Phenotypic means (SD) for BW, WW, and YW were 31.4 (1.6), 175 (32), and 333 (70) kg, respectively. Direct heritability, maternal heritability, and the genetic correlation between additive direct and maternal effects were 0.59, 0.17, and -0.90 for BW; 0.29, 0.17, and -0.90 for WW; and 0.24, 0.15, and -0.86 for YW, respectively. The results showed moderate direct and maternal heritabilities for the studied traits. The genetic correlations between direct and maternal effects were negative and high for all the traits indicating important tradeoffs between direct and maternal effects. There are significant possibilities for genetic progress for the growth traits studied if they are included in a breeding program considering these associations.
Crystallographic evidence for the proposed host behaviour of ptilomycalin A (1996)

P. J. Murphy, H. L. Williams, D. E. Hibbs, M. B. Hursthouse and K. M. A. Malik, Chem. Commun., 1996, 445 DOI: 10.1039/CC9960000445
Technical analysis on future challenges and opportunities in live P2P streaming (2014)

This paper presents a technical analysis on live P2P streaming techniques. The paper provides an overview on existing P2P solutions with more focus on solutions proposed for Dynamic Adaptive Streaming over HTTP (DASH). DASH is currently the state of the art protocol for adaptive streaming. The paper highlights the gains and challenges of live P2P streaming and discusses how P2P streaming serves as an attractive solution for video streaming and broadcasting in high density traffic. The paper describes in deeper detail some of the recently introduced techniques for live P2P video streaming and discusses how clients share their downloaded content in more efficient ways thus offloading content servers and communication networks. This paper illustrates the various challenges associated with P2P video streaming and provides a comparison between existing solutions.
Transient Health Shocks and Agricultural Labor Demand in Rice-producing Households in Mali (2006)

Malaria and other transient illnesses have been recognized as factors constraining economic development in tropical countries. The purpose of this paper is to determine the direct and the indirect impact of transient illness shocks, caused primarily by malaria but also including other tropical illness, on family labor use in irrigated rice production in Mali. Family labor is the most important factor of production used in rice production in Mali and transient illness shocks may negatively impact labor supply, production and hence household welfare derived from agricultural income and consumption. Two labor demand models are estimated to determine whether illness does indeed reduce labor supply: one where the dependent variable only includes family labor and a second that combines family and hired labor. These models can be used to test two sets of hypotheses on the relationship between illness and labor supply. First, we hypothesize that short-term transient illness shocks affect household labor supply implying that intrahousehold coping mechanisms are not wholly effective. Secondly, we hypothesize that hired labor markets are ineffective in mitigating illness shocks. We find that direct and indirect health shocks reduce the effective supply of labor and that neither household nor market supply of labor can mitigate these shocks.
A Guideline to Establish DGPS Reference Station Requirements (2007)

After Selective Availability (SA) was turned off, the rate of change with time of the DGPS common errors (atmospheric delay, satellite orbit and clock error) became quite slow. This inevitably leads to a requirement to modify various configurations of DGPS correction message broadcasting, and reference station (RS) managers need to examine the characteristics of GPS measurement errors with SA-off. GPS error sources are temporally and spatially decorrelated, so the DGPS user position accuracy is varied by the baud-rate of the RS, the distance between the user and the station, and the noise statistics of the receiver. We identify the minimum and maximum size of correction data, interval time, the coverage range and the baud-rate that are required to maintain the existing DGPS service. Moreover, the compatibility and accuracy can be assessed to meet the users' requirements without measurements being needed. The results in this paper are used in the study and testing for the redesign of United States Coast Guard (USCG) RS. We hope that our study will be a great help in determining the flexible factors of both the RS and the user.
A modified quadrupole mass spectrometer with custom RF link rods driver for remote operation (1973)

A commercial quadrupole residual gas analyzer system has been upgraded for operation at extended cable lengths. Operation inside a vacuum chamber for the standard quadrupole nude head is limited to approximately 2 m from its externally located rf/dc generator because of the detuning of the rf oscillator circuits by the coaxial cable reactance. The advance of long distance remote operation inside a vacuum chamber for distances of 45 and 60 m was made possible without altering the quadrupole's rf/dc generator circuit by employing an rf link to drive the quadrupole rods. Applications of the system have been accomplished for in situ space simulation thermal/vacuum testing of sophisticated payloads.
Cloning and characterization of a cDNA encoding transformation-sensitive tropomyosin isoform 3 from tumorigenic human fibroblasts. (1988)

We isolated a cDNA clone from the tumorigenic human fibroblast cell line HuT-14 that contains the entire protein coding region of tropomyosin isoform 3 (Tm3) and 781 base pairs of 5'- and 3'-untranslated sequences. Tm3, despite its apparent smaller molecular weight than Tm1 in two-dimensional gels, has the same peptide length as Tm1 (284 amino acids) and shares 83% homology with Tm1. Tm3 cDNA hybridized to an abundant mRNA of 1.3 kilobases in fetal muscle and cardiac muscle, suggesting that Tm3 is related to an alpha fast-tropomyosin. The first 188 amino acids of Tm3 are identical to those of rat or rabbit skeletal muscle alpha-tropomyosin, and the last 71 amino acids differ from those of rat smooth muscle alpha-tropomyosin by only 1 residue. Tm3 therefore appears to be encoded by the same gene that encodes the fast skeletal muscle alpha-tropomyosin and the smooth muscle alpha-tropomyosin via an alternative RNA-splicing mechanism. In contrast to Tm4 and Tm5, Tm3 has a small gene family, with, at best, only one pseudogene.
ChemInform Abstract: STEREOCHEMICAL COURSE OF THE CHEMICAL AND CATALYTIC REDUCTION OF 11‐OXO‐5α,14β‐CHOLEST‐8‐EN‐3β‐OL. SYNTHESIS OF 8α,9α,14β‐, 8α,9β,14β‐, AND 8β,9α,14β‐STEROIDS (1979)

Abstract Die Reduktion des Oxo‐Steroids (II) zu (I) bzw. (III) und (IV) sowie zahlreiche Folgereaktionen werden beschrieben.
Characterization and development of photoactivatable fluorescent proteins for single-molecule–based superresolution imaging (2014)

Photoactivatable fluorescent proteins (PAFPs) have been widely used for superresolution imaging based on the switching and localization of single molecules. Several properties of PAFPs strongly influence the quality of the superresolution images. These properties include (i) the number of photons emitted per switching cycle, which affects the localization precision of individual molecules; (ii) the ratio of the on- and off-switching rate constants, which limits the achievable localization density; (iii) the dimerization tendency, which could cause undesired aggregation of target proteins; and (iv) the signaling efficiency, which determines the fraction of target-PAFP fusion proteins that is detectable in a cell. Here, we evaluated these properties for 12 commonly used PAFPs fused to both bacterial target proteins, H-NS, HU, and Tar, and mammalian target proteins, Zyxin and Vimentin. Notably, none of the existing PAFPs provided optimal performance in all four criteria, particularly in the signaling efficiency and dimerization tendency. The PAFPs with low dimerization tendencies exhibited low signaling efficiencies, whereas mMaple showed the highest signaling efficiency but also a high dimerization tendency. To address this limitation, we engineered two new PAFPs based on mMaple, which we termed mMaple2 and mMaple3. These proteins exhibited substantially reduced or undetectable dimerization tendencies compared with mMaple but maintained the high signaling efficiency of mMaple. In the meantime, these proteins provided photon numbers and on-off switching rate ratios that are comparable to the best achieved values among PAFPs.
Remotely reprogrammable sensors for structural health monitoring (2004)

Wireless sensors can improve our ability to monitor critical civil infrastructure, including highways &amp;amp; bridges. We have previously reported on highly miniaturized, wireless strain, acceleration, and inclination sensing systems capable of providing low &amp;amp; high speed data update rates. Signal conditioning, multiplexing, A/D conversion, processing, amplifying, data logging, and bi-directional wireless communications are fully integrated. Each node includes a unique address (RFID), allowing a single base station to orchestrate data collection from thousands of distinct sensing nodes. In order to enhance these capabilities, we have produced a new base station with remote cellular telephone interface. This allows access to the sensing network from anywhere where cellular communications are available. Key operating parameters such as triggering, data sampling rates, data sampling duration, continuous streaming duration, and number of active channels may all be programmed remotely. The base station can issue broadcast commands, such as “wake up, begin data logging, or “go back to sleep”. Node specific commands include “download data from node, remove offsets from a node’s channel, increase gain on a node’s channel”. These capabilities allow a remote sensing network to be deployed in the field and remotely adapted over time to meet the customer’s unique SHM requirements.