gebhart/patrepeval huggingface dataset:
PP.LB02.03 (2015)

Objective: Circadian pattern of BP is characterized by a nocturnal decrease of BP of 10–20% compared with diurnal BP (dipper). Subjects with nocturnal hypertension (>120/70) are at risk of systemic organ damage. Transversal clinical study of incident patients in our cardiovascular risk consultation office. To describe distribution of HBP classical pattern (dipper vs. non-dipper/riser) and nocturnal HBP(NHBP) with ABPM and to analyze clinical parameters associated with those patterns. Design and method: We collected data from all patients recently diagnosed with HBP, they were distributed according to classical pattern and also to NHBP. We gathered demographic characteristics of our population/albuminuria/BMI/DM/medication to treat HBP. Results: 96 patients (63% male, age 52.36 years SD:14.8); daily SBP 135.7 mmHg (SD:12.8), daily DBP 82 mmHg (SD:9.1); nocturnal SBP 126.0 mmHg (SD:16.12), nocturnal DBP nocturnal 72.4 mmHg (SD:9.9). 31% of dipper patients presented NHBP, which is considered a CV risk factor, however NHBP was undetected by the classical pattern classification. There were 27% classified as non dipper that did not have NHBP. According to the classical pattern: the presence of albuminuria (ACC > 30 mg/g) is associated with nondipper/riser pattern:(45.7% nondipper/riser vs. 20% dipper, p < 0.05).No differences were found in both groups in terms of BMI nor ongoing treatment with ACE inhibitors and ARBs. According to NHBP pattern yes/no: the presence NHBP is associated with higher prevalence of albuminuria(46%) compared with the absence of NHBP (16,1%;p < 0.05). Moreover patients with NHBP have a higher BMI than patients that do not have NHBP (75%vs.55.3%;p < 0.05). BMI was not a confounding factor, which is proven by the fact that 100% of patients with BMI < 25 presented albuminuria(p < 0.05). Regarding patients with BMI < 25,100% of the patients with NHBP presented albuminuria and only 28.6% of patients with non-dipper/riser pattern presented albuminuria. Conclusions: Stratification according to the presence of NHBP shows more association with albuminuria than the classical pattern does, which is more patent in patients with BMI < 25. Classification of patients using both methods can be discordant. Due to this, we should take into account the presence of NHBP as a cardiovascular risk factor whenever interpreting ABPM.
Effect of multiblade slurry saw induced damage on silicon solar cells (1978)

A correlation between the optimum etch loss and the depth of damage is established using wafers produced by the Multiblade Slurry (MBS) and the Internal Diameter (ID) saws. The observations are based on the measurement of the performance of solar cells fabricated on these wafers. Sample preparation and test results are described and the following conclusions are made: (1) the amount of silicon removal necessary for optimum solar cell performance coincides with the depth of saw-induced damage; (2) optimization of cell performance is not affected by the method of silicon removal; (3) sawing conditions should be optimized to minimize the extent of saw-induced damage; (4) the MBS saw is found to induce damage to a lesser extent; (5) since the extent of damage in MBS-sawn wafers is in the limit of etch loss required in texture etching, it is possible to achieve optimum improvement in cell performance by merely texture etching the surface of as-sawn wafers.
PREDOMINANCE OF ZOOGLOEA SP. DURING AEROBIC GRANULAR SLUDGE BIOFILMS DEVELOPMENT FOR WASTEWATER TREATMENT (2010)

Aerobic granular sludge (AGS) biofilm process is a sustainable technology for full biological nutrients removal (BNR) from municipal and agro-industrial wastewater, and for secondary clarification in single sequencing batch reactors (SBR). Fundamental research on the structure and dynamics of microbial communities inside AGS biofilms remains to be performed in addition to full-scale implementation, in order to link process conditions and reactor efficiency, and to tailor metabolic activities for stable treatment performance. Ten bubble column SBRs were run during three successive campaigns for (i) cultivating AGS, (ii) optimizing the AGS biofilm stability, and (iii) investigating process conditions favouring full BNR. Molecular ecology analyses on eubacterial communities performed during each first month of start-up revealed that optimally dense and fast-settling AGS biofilms were composed of 60-90% of Zoogloea sp. of the Î²-proteobacterial order Rhodocyclales, and of less than 20% of undesired Burkholderiales filamentous bulking heterotrophic bacteria. Zoogloea sp. was favourably selected by combining optimal process parameters: inoculum from a full BNR plant, 20Â°C, 60min- slow plug-flow anaerobic influent feeding regime, 0.018 m s-1 air superficial velocity, and settling time lower than 5 min. The application of a short settling phase induced a washout dynamics between the times of SBR inoculation and AGS nucleation. This low initial sludge retention time selected for a fast-settling biomass, but hampered the growth of relevant phosphorus-accumulating organisms, nitrifiers and denitrifiers. Organic carbon was fully removed, while phosphorus and nitrogen were not treated during the first 70 d. Zoogloea-like organisms can store soluble volatile fatty acids into intracellular polyhydroxyalcanoates (PHA). PHA-accumulating bacteria are expected to be denser and to settle faster than other species, and can stay in the AGS-SBR system during the initial washout dynamics. Zoogloea sp. can produce in addition extracellular polysaccharide polymers which could help to form and stabilize the early AGS biofilm structure.
The Interplay of Symbolic and Subsymbolic Processes in Anagram Problem Solving (2000)

Although connectionist models have provided insights into the nature of perception and motor control, connectionist accounts of higher cognition seldom go beyond an implementation of traditional symbol-processing theories. We describe a connectionist constraint satisfaction model of how people solve anagram problems. The model exploits statistics of English orthography, but also addresses the interplay of subsymbolic and symbolic computation by a mechanism that extracts approximate symbolic representations (partial orderings of letters) from subsymbolic structures and injects the extracted representation back into the model to assist in the solution of the anagram. We show the computational benefit of this extraction-injection process and discuss its relationship to conscious mental processes and working memory. We also account for experimental data concerning the difficulty of anagram solution based on the orthographic structure of the anagram string and the target word. ...
Echtzeitnachweis von Änderungen im Protein‐Wassernetzwerk während der Proteinfaltung mit Terahertz‐Absorptionsspektroskopie (2008)

Rasch umgesehen: Die kinetische Terahertz-Absorption (KITA) wird eingesetzt, um die Dämpfung und Phasenverschiebung eines elektrischen Terahertz-Feldes, das ein Protein während seiner Faltung transmittiert, aufzuzeichnen. Ein Vergleich mit Kleinwinkelröntgenstreuung, Fluoreszenz- und Circulardichroismusdaten belegt, dass KITA Umorientierungen der Solvatwasser-Protein-Wechselwirkungen in einer Frühphase von Proteinkollaps und Sekundärstrukturbildung detektiert. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
General discussion (1981)

G. C. Bond, W. M. H. Sachtler, O. Zahraa, R. Burch, J. J. Rooney, B. C. Gates, V. M. Gryaznov, V. Ponec, L. Guczi, Z. Paál, R. A. van Santen, G. Maire, P. B. Wells, H. Knözinger, J. Cunnigham, S. D. Jackson, M. W. Roberts, J. M. Thomas, A. P. G. Kieboom and V. M. Gryaznov, Faraday Discuss. Chem. Soc., 1981, 72, 79 DOI: 10.1039/DC9817200079
Skeletal Substitution as a Route to New Inorganic Heterocycles:  The Unexpected Replacement of Boron in a Borazine-like Environment (1997)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTSkeletal Substitution as a Route to New Inorganic Heterocycles: The Unexpected Replacement of Boron in a Borazine-like EnvironmentDerek P. Gates, Louise M. Liable-Sands, Glenn P. A. Yap, Arnold L. Rheingold, and Ian MannersView Author Information Department of Chemistry University of Toronto, 80 St. George Street Toronto, Ontario M5S 3H6, Canada Department of Chemistry and Biochemistry University of Delaware, Newark, Delaware 19716 Cite this: J. Am. Chem. Soc. 1997, 119, 5, 1125–1126Publication Date (Web):February 5, 1997Publication History Received24 September 1996Published online5 February 1997Published inissue 1 February 1997https://pubs.acs.org/doi/10.1021/ja9633427https://doi.org/10.1021/ja9633427rapid-communicationACS PublicationsCopyright © 1997 American Chemical SocietyRequest reuse permissionsArticle Views258Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Boron,Cations,Crystal structure,Molecular structure,Substitution reactions Get e-Alerts
Rewarding probabilistic hybrid automata (2013)

The joint consideration of randomness and continuous time is important for the formal verification of many real systems. Considering both facets is especially important for wireless sensor networks, distributed control applications, and many other systems of growing importance. Apart from proving the quantitative safety of such systems, it is important to analyze properties related to resource consumption (energy, memory, bandwidth, etc.) and properties that lie more on the economical side (monetary gain, the expected time or cost until termination, etc.). This paper provides a framework to decide such reward properties effectively for a generic class of models which have a discrete-continuous behaviour and involve both probabilistic as well as nondeterministic decisions. Experimental evidence is provided demonstrating the applicability of our approach.
Gene Therapy for Rett Syndrome: Prospects and Challenges (2015)

Rett syndrome (RTT) is a neurological disorder that affects females and is caused by lossof-function mutations in the X-linked gene MECP2. Deletion of Mecp2 in mice results in a constellation of neurological features that resemble those seen in RTT patients. Experiments in mice have demonstrated that restoration of MeCP2, even at adult stages, reverses several aspects of the RTT-like pathology suggesting that the disorder may be inherently treatable. This has provided an impetus to explore several therapeutic approaches targeting RTT at the level of the gene, including gene therapy, activation of MECP2 on the inactive X chromosome and read-through and repair of RTT-causing mutations. Here, we review these different strategies and the challenges of gene-based approaches in RTT.
Incentive mechanism for collective coordination in an urban intelligent transportation system using G-networks (2020)

Although the abilities of human beings as participants in urban traffic, when they take decisions and interact with the transportation infrastructure and other vehicles, have been greatly amplified by powerful portable devices and efficient human-machine interfaces, the intelligence of vehicle drivers and pedestrians and their possible pro-social behaviour such as helpfulness and sense of duty, have been excluded in previous studies of Intelligent Transportation Systems (ITS). Thus the robustness of an ITS has not been evaluated as a function of the likelihood that participants follow instructions. Moreover, much effort has been dedicated to the use of Artificial Intelligence, while in fact many tasks can be easily accomplished by road users in the system who use ordinary human intelligence. Hence, in this paper, we propose a reward mechanism to integrate the intelligence of human road users into a large-scale transportation system to improve the effectiveness and robustness of the system by introducing a transportation-related task publishing system which is assisted by a queueing network model. The experimental results show that the use of a reward mechanism can significantly improve the performance of the transportation system in terms of average travel time of vehicles and the average response time to various tasks.
An Introduction to Neurosurgery. (1971)

The author directs his attention to the needs of the younger surgeon beginning neurosurgical training or others associated with neurosurgery peripherally such as general house officers, neuroradiologists, neurologists, and pathologists. He admittedly does not attempt to be comprehensive but does cover all important aspects of the subject and provides a capsule view of conditions encountered frequently. Important areas are given expanded and up-to-date treatment, and modern trends in diagnosis including brain scanning and neuroradiology are amply covered. Points of practical interest to nonsurgeons such as diagnostic and postoperative problems are also stressed. Neurosurgical emergencies and other urgent procedures are presented in enough detail to be of value to other physicians who encounter such problems in a general surgical or emergency unit. Principle physiological processes useful in understanding signs and symptoms of intracranial problems are presented in a lucid and concise fashion. The treatment of more common conditions such as intracranial
Amphoterics in household detergents (1991)

Abstract Amphoteric surfactants are widely known for their extreme skin kindness, decreasing the irritation of otherwise irritant surfactants, especially anionics, giving low‐irritant shampoo ingredients. New high quality amphoteric compounds have been developed. These new amphoterics offer exciting possibilities in several new application areas. Considerable development work has been undertaken to investigate new detergent formulations based on these novel amphoterics. Because of the very low concentration of Ampholak 7TX, the formulations give most effective products with low biological load. Data concerning the increasingly important subject of biodegradability and toxicity are shown. This includes both primary and inherent biodegradability and toxicity of metabolites.
Weight Uncertainty in Neural Networks (2015)

We introduce a new, efficient, principled and backpropagation-compatible algorithm for learning a probability distribution on the weights of a neural network, called Bayes by Backprop. It regularises the weights by minimising a compression cost, known as the variational free energy or the expected lower bound on the marginal likelihood. We show that this principled kind of regularisation yields comparable performance to dropout on MNIST classification. We then demonstrate how the learnt uncertainty in the weights can be used to improve generalisation in non-linear regression problems, and how this weight uncertainty can be used to drive the exploration-exploitation trade-off in reinforcement learning.
Repeated Famotidine Administration Results in a Diminished Effect on Intragastric pH in Dogs (2016)

Continued administration of famotidine results in a diminished effect on intragastric pH in dogs. Caution is advised when recommending long-term, daily oral administration of famotidine to dogs.
Development of Highly Reactive Nanometer Fe-Based Catalysts for Coal Liquefaction (2008)

This paper describes research involving the liquefaction of coal and the removal of oxygen from coal product constituents. Subbituminous Coal and early stage coal liquefaction products contain a substantial fraction of hydroxy-substituted aromatic hydrocarbons (phenols). An important reaction for upgrading of coal-derived organic materials is to remove oxygen groups. This paper describes the hydro-deoxygenation of naphthols and the liquefaction of subbituminous Wyodak coal using a catalyst prepared by in-situ sulfidation of nanometer scale 6-line iron ferrihydrite. The FeS catalyst enables the conversion of naphthol in substantial yields to tetralin and naphthalene at 400 degrees C in 9,10-dihydrophenanthrene. The kinetics and procedures to observe coal liquefaction and hydro-deoxygenation, and the effects of in-situ sulfidation on conversion kinetics are described.
Biosynthesis of antifreeze polypeptides in the winter flounder (1986)

The precursor proteins for winter flounder antifreeze polypeptide (AFP) were isolated from liver using gel filtration chromatography and reverse-phase high-performance liquid chromatography. Two major pro-antifreezes (Mr 5000), corresponding to the precursors for AFP-6 and AFP-8, were characterized by amino acid analyses and automated Edman degradation. These precursors showed significant antifreeze activity. The pro-antifreezes were synthesized in the liver seasonally as demonstrated by immunoblotting and in vitro liver incorporation studies. No mature AFP were detected in liver, thus indicating that the processing of pro-antifreezes, including amidation of the C-termini, occurred mainly in the serum. The function(s) of the prosequences, if any, remain unclear.
Modeling, Implementation and simulation of virtual factory based on colored timed Petri net (2004)

The Real-time Colored Petri Net (RTCPN), a modification of traditional Colored Timed Petri net, is proposed to describe virtual factory. In RTCPN, firing discipline differs from traditional way in that the concept of time-enabled transition is introduced to implement real-time simulation. In this paper, we address how to describe virtual factory using RTCPN model. Combined with block diagram, the concept of virtual place is also proposed to model large-scale factory rapidly and conveniently. At last, a Java-built-in implementation of RTCPN tool is developed and a Printed-Circuit-Board factory is given to investigate time cost of developed tool. Concurrent feature of RTCPN is also discussed to decrease simulation time and improved results shows its effectiveness.
Automatic Infant Face Verification via Convolutional Neural Networks (2018)

In this paper, we investigate how convolutional neural networks (CNN) can learn to solve the verification task for faces of young children. One of the main issues of automatic face verification approaches is how to deal with facial changes resulting from aging. Since the facial shape and features change drastically during early childhood, the recognition of children can be challenging even for human observers. Therefore, we design CNNs that take two infant photographs as input and verify whether they belong to the same child. To specifically train our CNNs to recognize young children, we collect a new infant face dataset including 4,528 face images of 42 subjects in the age range of 0 to 6 years. Our results show an accuracy of up to 85 percent for face verification using our dataset with no overlapping subjects between the training and test data, and 72 percent in the FG-NET dataset for the age range from 0 to 4 years.
IgA-specific helper activity of T alpha cells in human peripheral blood. (1981)

A subpopulation of human T lymphocytes that express receptors of immunoglobulin A (T alpha cells) was separated by a FACS using FITC-conjugated human IgA myeloma protein in order to determine whether they have helper activity for in vitro immunoglobulin synthesis in comparison with a T alpha cell population separated by rosette formation using PTN-ORBC conjugated with MOPC-315 mouse IgA myeloma protein. FACS-separated T alpha cells have IgA specific helper activity, whereas rosette-separated T alpha cells have polyclonal helper activity for in vitro immunoglobulin synthesis in PWM-stimulated B cells. The polyclonal helper activity observed in rosette-separated T alpha cells might be due to contamination of non-T alpha cells in the T alpha cell fraction. It is concluded that purified T alpha cells in normal human peripheral blood show IgA-specific helper activity in vitro.
Tunneling Anisotropic Magnetoresistance Driven by Resonant Surface States: First-Principles Calculations on an Fe(001) Surface (2007)

Fully relativistic first-principles calculations of the Fe(001) surface demonstrate that resonant surface (interface) states may produce sizable tunneling anisotropic magnetoresistance in magnetic tunnel junctions with a single magnetic electrode. The effect is driven by the spin-orbit coupling. It shifts the resonant surface band via the Rashba effect when the magnetization direction changes. We find that spin-flip scattering at the interface is controlled not only by the strength of the spin-orbit coupling, but depends strongly on the intrinsic width of the resonant surface states.
Physical Signals May Affect Mesenchymal Stem Cell Differentiation via Epigenetic Controls (2017)

Marrow mesenchymal stem cells supply bone osteoblasts and adipocytes. Exercise effects to increase bone and decrease fat involve transfer of signals from the cytoplasm into the nucleus to regulate gene expression. We propose that exercise control of stem cell fate relies on structural connections that terminate in the nucleus and involve intranuclear actin structures that regulate epigenetic gene expression.
The conservative substitution Asp-645→Glu in lysosomal α-glucosidase affects transport and phosphorylation of the enzyme in an adult patient with glycogen-storage disease type II (1993)

Glycogen-storage disease type II (GSDII) is caused by the deficiency of lysosomal alpha-glucosidase (acid maltase). This paper reports on the analysis of the mutant alleles in an American black patient with an adult form of GSDII (GM1935). The lysosomal alpha-glucosidase precursor of this patient has abnormal molecular features: (i) the molecular mass is decreased, (ii) the phosphorylation is deficient and (iii) the proteolytic processing is impaired. Sequence analysis revealed four mutations leading to amino acid alterations: Asp-645-->Glu, Val-816-->Ile, Arg-854-->Stop and Thr-927-->Ile. By using allele-specific oligonucleotide hybridization on PCR-amplified cDNA we have demonstrated that the Arg-854-->Stop mutation is located in one allele that is not expressed, and that the other allele contains the remaining three mutations. Each of the mutations was introduced in wild-type cDNA and expressed in COS cells to analyse the effect on biosynthesis, transport and phosphorylation of lysosomal alpha-glucosidase. The Val-816-->Ile substitution appeared to have no significant effect in contrast with results [Martiniuk, Mehler, Bodkin, Tzall, Hirshhorn, Zhong and Hirschhorn (1991) DNA Cell Biol. 10, 681-687] and was therefore defined as a polymorphism. The Thr-927-->Ile substitution deleting one of the seven glycosylation sites was found to be responsible for the decrease in molecular-mass, but not for the deficient proteolytic processing and phosphorylation. It did not cause the enzyme deficiency either. The third mutation leading to the Asp-645-->Glu substitution was proven to account in full for the observed defects in transport, phosphorylation and proteolytic processing of the newly synthesized alpha-glucosidase precursor of the patient.