gebhart/patrepeval huggingface dataset:
Mouse monoclonal antibodies to human epithelial differentiation antigens expressed on the surface of ovarian carcinoma ascites cells. (1987)

Four different human epithelial differentiation antigens (MT179, MW162, MW207, and MX35) have been defined by mouse monoclonal antibodies obtained from mice immunized with either an ovarian carcinoma cell line or fresh ovarian carcinoma cells. In an attempt to identify tissue-specific antigens restricted to ovarian epithelial cells, sections of a benign ovarian cyst were used as the initial target for screening hybridoma supernatants. The distribution of the antigens detected by these monoclonal antibodies was determined on frozen sections of 24 normal tissues and on 103 cultured cell lines of various histological types. In spite of the method used to select these monoclonal antibodies, they all reacted to some degree with normal epithelial cells in tissues other than ovary. All antibodies were unreactive with nonepithelial cells in frozen sections. These antibodies also reacted with frozen sections of most or all fresh ovarian carcinomas and benign ovarian cysts. All antibodies were unreactive with ABH, Lewis blood group-related antigens and appeared to be different in specificity from previously described well-characterized antigens of ovarian carcinoma cells. MW162 was characterized as a high-molecular-weight mucin-like molecule, and the determinant recognized is probably carbohydrate in nature. MW207 was identified as a Mr 37,000 protein. These monoclonal antibodies and 24 other previously derived antibodies that react with epithelial differentiation antigens were tested for reactivity with the surface of fresh ovarian carcinoma ascites cells and for nonreactivity with normal mesothelial cells. This assay was designed to select monoclonal antibodies that might be effective agents for i.p. therapy or radioimmunodetection of human ovarian carcinoma. Five antibodies with the desired specificity were selected; these were the four new antibodies described herein and MH99, which was characterized previously and recognizes a glycoprotein having Mr 38,000 and 29,000 subunits. The degree of heterogeneity of antigen expression on ascites carcinoma cell was dependent on the particular antigen being examined and was related to the biochemical nature of the antigen. In particular, most ABH and Lewis blood group-related antigens showed a striking degree of heterogeneity.
<title>Fiber optic sensing at Strathclyde: from ropes to eyes</title> (2002)

This paper briefly outlines some of the on-going research work in fiber optic sensor technology at the University of Strathclyde. Five principal themes are identified including two in distributed sensing examining liquid detection and mechanical strain detection, a highly multiplexed system for the detection of methane gas and two specialized point measurement systems, one to detect the presence of drugs in the eye and the other to facilitate the non-contact assessment of the mechanical properties of materials. These examples, whilst not exhaustive, represent the cross section of activities on-going at Strathclyde and the diversity of applications within which the group has become involved. The work described here is all current though some has been established for several years. Within it are contributions from several members of the Group and it includes interactions with many external organizations who are acknowledged within the paper.
Increase in brain-derived neurotrophic factor expression in early crack cocaine withdrawal (2013)

Recent reports suggest that brain-derived neurotrophic factor (BDNF) could be a biomarker for relapse, drug craving and withdrawal severity. In particular, elevated BDNF levels among former cocaine users have been associated with higher rates of relapse in 90 d. However, no data are available on BDNF levels at baseline and during crack cocaine withdrawal. This study evaluated BDNF among crack cocaine users during inpatient treatment, before and after withdrawal, vs. healthy controls. Clinical correlates with changes in BDNF levels were also assessed. Serum BDNF was evaluated in 49 male crack users on the first and last days of hospitalization and in 97 healthy controls. Serum BDNF was assayed using a sandwich ELISA kit. BDNF levels were significantly lower upon admission when compared to controls, even after adjustment for age, length of inpatient treatment, number of crack rocks used in the last 30 d, years of crack use and interaction between the latter two variables. At discharge, BDNF levels between patients and controls were similar. Number of crack rocks used in the last 30 d and years of crack use were inversely correlated with the outcome. Our findings show that BDNF levels increase during early crack cocaine withdrawal, at an inverse correlation with number of crack rocks used in the last 30 d and years of crack use.
NADH dehydrogenase deficiency results in low respiration rate and improved aerobic growth of Zymomonas mobilis (2008)

The respiratory chain of the ethanol-producing bacterium Zymomonas mobilis is able to oxidize both species of nicotinamide cofactors, NADH and NADPH. A mutant strain with a chloramphenicol-resistance determinant inserted in ndh (encoding an NADH : CoQ oxidoreductase of type II) lacked the membrane NADH and NADPH oxidase activities, while its respiratory D-lactate oxidase activity was increased. Cells of the mutant strain showed a very low respiration rate with glucose and no respiration with ethanol. The aerobic growth rate of the mutant was elevated; exponential growth persisted longer, resulting in higher biomass densities. For the parent strain a similar effect of aerobic growth stimulation was achieved previously in the presence of submillimolar cyanide concentrations. It is concluded (i) that the respiratory chain of Z. mobilis contains only one functional NAD(P)H dehydrogenase, product of the ndh gene, and (ii) that inhibition of respiration, whether resulting from a mutation or from inhibitor action, stimulates Z. mobilis aerobic growth due to redirection of the NADH flux from respiration to ethanol synthesis, thus minimizing accumulation of toxic intermediates by contributing to the reduction of acetaldehyde to ethanol.
ChemInform Abstract: Novel Route to Hydroxy(keto)ethylene Dipeptide Isosteres Through the Reaction of N‐BOC‐β‐lactams with Enolates. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Optical pumping in nitrogen-doped GaP (1975)

We report on the results of optical-pumping experiments in GaP doped with the isoelectronic impurity nitrogen. In the first experiment we have measured the saturation of absorption at the $A$ bound exciton as a function of pump intensity, using as the pump a pulsed dye laser tuned to the $A$ line. The observed saturation behavior is in quantitative accord with a simple three-level system involving the $A$ and $B$ bound-exciton level and the N ground state. The second experiment involves measuring the absorption at the $A$ line with a weak probe (a tunable dye laser) while the crystal is being pumped with an intense pump dye laser tuned above the indirect gap. In this case also the absorption saturates with increasing pump power and we can infer approximately 10% efficiency for the capture of excitons at N impurities. In this second experiment, a simple model predicts an amplification by a factor of 8.5 but none is observed. We conclude from these measurements that, when pumped above the indirect gap, the dominant excited state of N impurities in our crystal is a single electron trapped at N. We believe that this is caused by the presence of other impurities in the crystal and is not an intrinsic limitation of the system.
Prevalence of hyperuricemia in adolescents from 2000 to 2019 in Asia: A meta-analysis (2020)

Abstract Background : Studies of the prevalence of hyperuricemia in adolescents have been limited to specific areas and the prevalence in Asia is unknown. Objectives : This study was to determine the prevalence of hyperuricemia in adolescents in Asia from 2000 to 2019. Data sources : A comprehensive search was conducted to identify all relevant cross-sectional studies in Pubmed, Embase, and Cochrane library databases. Study eligibility criteria : “hyperuricemia” and “adolescent” were the two critical inclusion criteria. Participants, and interventions : Adolescents; Study appraisal and synthesis methods : Two reviewers independently extracted data and assessed study quality using STROBE check list. Extracted information included the first author, study year, country, publication year, sample size, number of cases, and age of onset. Heterogeneity among studies was evaluated using the Q test and quantified using the I 2 statistic. Subgroup analyses were performed to identify the source of the heterogeneity. The possibility of publication bias was assessed using Egger’s test. Results : The meta-analysis included 11 articles. The pooled prevalence of hyperuricemia in adolescents in Asia was 15.4% (95% CI 9.5-21.2%) and the prevalence of adolescents in Taiwan was higher than that in mainland China. The prevalence in coastal areas was higher than that in inland areas. The prevalence of men was higher than that of women. After excluding the high prevalence study in Taiwan, the prevalence of adolescents has been increasing year by year. Publication bias was observed but the results did not change after a trim and fill test, indicating that the impact of this bias was likely insignificant. Limitations: The diagnostic criteria for hyperuricemia for adolescents varied among the studies; some studies used their own cut-off values for hyperuricemia in adolescents. Conclusions and implications of key findings: Hyperuricemia prevalence in adolescents is high and continues to increase. The prevalence varies with geography, gender, and time. Effective measures should be taken to prevent any further increase in the incidence of adolescent hyperuricemia. Systematic review registration number : Not applicable.
Improving speech intelligibility in noise by SII-dependent preprocessing using frequency-dependent amplification and dynamic range compression (2013)

In this contribution, a new preprocessing algorithm to improve speech intelligibility in noise is proposed, which maintains the signal power before and after processing. The proposed AdaptDRC algorithm consists of two timeand frequency-dependent stages, which are both functions of the estimated SII. The first stage applies a timeand frequency-dependent amplification, while the second stage applies a timeand frequency-dependent dynamic range compression (DRC). Experiments with a competing speaker (CS) and a speech-shaped noise (SSN) show an increase in speech intelligibility for a wide range of SNRs for four different objective measures that are correlated with speech intelligibility. Listening tests conducted within the framework of the Hurricane Challenge with 175 subjects confirm these findings and show improvements of up to 20.5% in intelligibility for SSN and 12.3% for CS.
Using Windows NT for real-time applications: experimental observations and recommendations (2002)

Windows NT was not designed as a real time operating system, but market forces and the acceptance of NT in industrial applications have generated a need for achieving real time functionality with NT. As its use for real time applications proliferates, based on an experimental evaluation of NT, we quantitatively characterize the obstacles placed by NT. As a result of these observations, we provide a set of recommendations for users to consider while building real time applications on NT. These are validated by the use of NT for a prototype application involving real time control that includes multimedia information processing. The results of the above study should provide system designers with guidelines, as well as insight, into the design of an architecture based on NT for supporting applications with components having real time constraints.
Colon Cancer Screening Practices Following Genetic Testing for Hereditary Nonpolyposis Colon Cancer (HNPCC) Mutations (2004)

Genetic testing may motivate increased colonoscopic screening among HNPCC mutation carriers. Increased efforts may be needed to assess patients' family histories of colon cancer and provide appropriate referrals for genetic counseling and testing to target colonoscopic screening to high-risk individuals.
Intra-Ring Variations and Interrelationships for Selected Wood Anatomical and Physical Properties of Thuja Occidentalis L. (2019)

Intra-ring variation in wood density and tracheid anatomical properties and wood property interrelationships were investigated in Thuja occidentalis L. Samples were taken from three stands in Abitibi–Témiscamingue, Quebec, Canada. The structure of T. occidentalis wood is simple, homogeneous and uniform, which is desirable for wooden structures that require wood uniformity. From early- to latewood, cell and lumen diameter decreased, while cell wall thickness increased. These changes led to an increase of the cell wall proportion. Wood ring density and width interrelationships were weaker in mature wood compared to juvenile wood. Earlywood density is the more important in determining mature wood density than latewood density and proportion. Earlywood density explains 92% and 89% of the variation in juvenile and mature wood density, respectively. The negative relationship between ring density and width, although significant, was low and tends to weaken with increasing tree age, thus providing the opportunity for silvicultural practices to improve both growth and wood density. Ring width was positively and strongly correlated to early- and latewood width, but negatively correlated to tracheid length and latewood proportion. Accordingly, increases in ring width produce smaller tracheids and wider earlywood without a corresponding increase in latewood. Practical implications of the results are discussed.
Multicast network connection architecture (1995)

IBM Networking BroadBand Services (NBBS) is a comprehensive networking architecture designed for high-speed networks. To meet the demands of multicast communication applications, e.g., video on demand, software distribution, and video conferencing, NBBS multicast services provide support for efficient best-effort and guaranteed quality-of-service (QOS) multipoint network connections. The NBBS multicast services consist of set management services and multicast network connection services. Set management services provide the ability to create and manage groups of users who are interested in participating in multicast activities. Multicast network connection services use the group membership information provided by set management services to support multiple network connections per group and to provide supporting services such as nondisruptive path switching, path preemption, and bandwidth management. The multicast network connection services support the multicast signaling requirements defined by the asynchronous transfer mode user-to-network interface (ATM UNI) specifications. This paper gives an overview of the NBBS multicast connection services. Set concepts are introduced, an overview of set management protocols is given, and the value of set management services in establishing multicast network connections is explained. Finally, multicast network connection protocols that establish, maintain, and terminate multicast network connections are described.
LASER ION PRODUCTION AS THE INJECTOR FOR CANCER THERAPY SYNCHROTRON (2002)

Ion production by focusing high-power short-pulse laser is investigated as an injector for pulse synchrotron dedicated for cancer therapy. Combination of phase rotation and electron beam cooling is proposed as the scheme to reduce the energy spread and make acceptance matching with the synchrotron. Threshold power per pulse to realize target normal sheath acceleration and conversion efficiency of laser-power to ion energy need still further experimental investigation with precise control of pre-pulse
Prospective development and validation of a liquid immune profile-based signature (LIPS) to predict response of patients with recurrent/metastatic cancer to immune checkpoint inhibitors (2021)

NCT03453892.
Effect of surface treatment of printed Ag Schottky contacts on n-GaN epitaxial layers using Ag nanoink: Two dimensional characterization by scanning internal photoemission microscopy (2018)

We report the basic electrical characteristics of Ag Schottky contacts printed on n-GaN epitaxial wafers using Ag nanoink with surface treatment using HCl or an organic solvent. The Ag Schottky contacts treated with HCl showed better current–voltage characteristics and a larger Schottky barrier height than those treated with the organic solvent. Scanning internal photoemission microscopy revealed that the HCl-treated samples exhibited a higher uniformity owing to their higher wettability to the Ag nanoink and electrodes than the organic-solvent-treated samples. These results indicate that the removal of surface oxide layers using HCl is effective even though the GaN surface is printed and annealed in air.
Environmental and Agronomic Implications of Water Table and Nitrogen Fertilization Management (2002)

Nitrate (NO3-) pollution of surface and subsurface waters has become a major problem in agricultural ecosystems. Field trials were conducted from 1996 to 1998 at St-Emmanuel, Quebec, Canada, to investigate the combined effects of water table management (WTM) and nitrogen (N) fertilization on soil NO3- level, denitrification rate, and corn (Zea mays L.) grain yield. Treatments consisted of a combination of two water table treatments: free drainage (FD) with open drains at a 1.0-m depth from the soil surface and subirrigation (SI) with a design water table of 0.6 m below the soil surface, and two N fertilizer (ammonium nitrate) rates: 120 kg N ha(-1) (N120) and 200 kg N ha(-1) (N200). Compared with FD, SI reduced NO3(-)-N concentrations in the soil profile by 37% in spring 1997 and 2% in spring 1998; and by 45% in fall 1997 and 19% in fall 1998 (1 mg NO3(-)-N L(-1) equals approximately 4.43 mg NO3- L(-1)). The higher rate of N fertilization resulted in greater levels of NO3(-)-N in the soil solution. Denitrification rates were higher in SI than in FD plots, but were unaffected by N rate. The N200 rate produced higher yields than N120 in 1996 and 1997, but not 1998. Corn yields in SI plots were 7% higher than FD plots in 1996 and 3% higher in 1997, but 25% lower in 1998 because the SI system was unable to drain the unusually heavy June rains, resulting in waterlogging. These findings suggest that SI can be used as an economical means of reducing NO3- pollution without compromising crop yields during normal growing seasons.
Selective-Ultratrace Detection of Metal Ions with SERS (1991)

We report the results from experiments involving the detection of metal ions with a Surface-Enhanced Raman Spectroscopic indicator (SERS indicator). Comparisons of metals showed that the SERS effect can be used to selectively detect metal ions according to their ionic radius. We determined a resolving power for separating the alkaline earth series. The results indicate that the resolving power of the SERS approach is superior to that of absorption spectroscopy. Quantitatively, under our experimental conditions, we found a detection limit of 270 ppb for Pb 2+ and 85 ppb for Cu 2+ with the indicator Eriochrome Black T.
Embracing Novel Technologies in Dentistry and Orthodontics (2020)

https://deepblue.lib.umich.edu/bitstream/2027.42/153991/1/56th volume CF growth series FINAL 02262020.pdf
Auditory Noise Associated With MR Procedures: A Review (2000)

This review article discusses the various types of acoustic noise produced during the operation of MR systems, describes the characteristics of the acoustic noise, and presents information regarding noise control techniques. In addition, the problems related to acoustic noise for patients and healthcare workers are discussed.
Prothymosin α: Efficient sequence determination by experimental and theoretical capillary electrophoretic support (1997)

A rapid and efficient primary structure elucidation of prothymosin (ProT alpha) and its enzymatic fragments was performed by a combination of matrix-assisted laser desorption ionization mass spectrometry (MALDI), automatic N-terminal Edman degradation, and the available theoretical predictions of electrophoretic mobility in capillary electrophoresis (CE) as a basis suggesting active sites of ProT alpha in the different bioassays.
Circuits and System Design of RF Polar Transmitters Using Envelope-Tracking and SiGe Power Amplifiers for Mobile WiMAX (2010)

This paper discusses the circuits and system design methodology of a highly-efficient wideband RF polar transmitter (TX) using the envelope-tracking (ET) technique for mobile WiMAX applications. Monolithic power amplifiers (PAs) are designed and fabricated in IBM 0.18 <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex Notation="TeX">$\mu{\rm m}$</tex></formula> SiGe BiCMOS technology, and a linear-assisted switch-mode envelope amplifier is applied to modulate the PA supply voltage to form the core of the RF polar TX. Nonlinearities caused by bandwidth limitation of the envelope amplifier and timing misalignment have been investigated. When driven by WiMAX 64QAM 8.75 MHz signals, the overall PAE of our ET-based polar TX system reaches 30.5% at 17 dBm average output power, while also meeting the stringent WiMAX linearity specs without using any predistortion. When the decresting algorithm using the soft limiter is applied to the baseband, the overall PAE increases to 33%, at the expense of a higher EVM of 4.9%. Based on measurement results, our ET-based polar TX system has demonstrated excellent efficiency with good linearity for high peak-to-average ratio (PAR) broadband signals when compared with the recent literature on state-of-the-arts polar TX designs.
Vyhodnocení vlastností tlakové vlny v lidském těle při různých excitacích. (2013)

Tato práce se zabývá problematikou měření rychlosti šíření pulzní vlny v lidském těle pomocí metody vícekanálové celotělové bioimpedance, která byla vyvinuta na ÚPT AV ČR,v.v.i. Hodnocení rychlosti šíření pulzní vlny může poskytnout důležité informace o stavu poddajnosti vyšetřovaných cév, což je jedním ze základních parametrů vypovídajícím o jejich fyziologickém stavu. Vyšetřování stavu cévního řečiště je v rámci včasné diagnostiky velmi důležité, protože jeho patologické stavy jsou hlavním přispěvatelem ke vzniku kardiovaskulárních chorob a následné úmrtnosti. Práce se věnuje teoretickému rozboru problematiky, následně jsou rozebrány dosud dostupné metody hodnocení stavu cévního řečiště využívající měření rychlosti šíření pulzní vlny a hlavní část práce tvoří problematika měření pomocí vícekanálové celotělové bioimpedance. V rámci této práce byl navrhnut a naprogramován protokol, který sumarizuje a vizualizuje získané informace a v současnosti slouží jako výstup z experimentálního měření pomocí této metody. Datový soubor pro statistické zpracování pozůstává z hodnot rychlostí šíření pulzní vlny u 35 zdravých dobrovolníků a následně jsou vyhodnoceny vlastnosti pulzní vlny při různých excitacích.