gebhart/patrepeval huggingface dataset:
Poly(silaethylene): A Novel Analog of Polyethylene (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPoly(silaethylene): A Novel Analog of PolyethyleneL. V. Interrante, H.-J. Wu, T. Apple, Q. Shen, B. Ziemann, D. M. Narsavage, and K. SmithCite this: J. Am. Chem. Soc. 1994, 116, 26, 12085–12086Publication Date (Print):December 1, 1994Publication History Published online1 May 2002Published inissue 1 December 1994https://pubs.acs.org/doi/10.1021/ja00105a072https://doi.org/10.1021/ja00105a072research-articleACS PublicationsRequest reuse permissionsArticle Views146Altmetric-Citations33LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Effect of maternal age on incidences of apoptotic and proliferative cells in trophoblasts of full-term human placenta (2001)

Advanced maternal age is known to be a risk factor for various kinds of obstetric complications, including placental dysfunction. As a first step towards determining the maternal age-related changes in placental, as well as trophoblastic function, we examined the incidences of apoptotic and proliferative cells in trophoblasts of placentae from women of various ages using the TUNEL method and immunohistochemistry for Ki-67 antigen. Tissue sections were collected from the placentae of healthy mothers with normal delivery of healthy babies so that the placental cell kinetics maintaining normal pregnancy and delivery could be studied. The TUNEL-positive cells of the placenta were syncytiotrophoblasts with clustering of nuclei and the TUNEL-positive index of these cells varied from 0.28-1.2%. This index revealed a significant inverse correlation with maternal age. In contrast, the Ki-67-positive index of mononuclear trophoblasts of the placenta ranged between 1.2-2.8% and showed a positive correlation with maternal age. Many of the apoptotic cells of placental villi expressed the pro-apoptotic Bak protein, but were negative for expression of the anti-apoptotic Bcl-2 protein. These results suggest that trophoblasts have higher proliferative activity in older mothers, with a normal process of pregnancy and delivery. The Bcl-2 family proteins could be important for the regulation of trophoblastic apoptosis, although the cellular and molecular mechanisms mediating maternal age-related changes of the placenta remain to be determined.
Sora Identity: Secure, Digital Identity on the Blockchain (2018)

Digital identity is the cornerstone of a digital economy. However, proving identity remotely is difficult to do. To complicate things further, identity is usually not a global, absolute construct, but the information shared with different parties differs, based on the relationship to the user. Therefore, a viable solution for digital identity should enable users to have full control over their personal information and share only the information that they wish to share with each service. Blockchain technology can help to realize a self-sovereign identity that puts the user in control of her information, by enabling a decentralized way to handle public key infrastructure. In the current contribution, we present the Sora identity system, which is a mobile app that utilizes blockchain technology to create a secure protocol for storing encrypted personal information, as well as sharing verifiable claims about personal information.
The Relationship Between the Pharmaceutical Properties and Dispensing of a Fine Granule. The Examination of the Evaluation Method for Dispensing of a Fine Granule. (1995)

Formulations were established to evaluate the dispensing characteristics of fine granules.The formulations were prepared mainly according to “the Standard Formula for Fine Granules” established by the Particulate Preparation and Designing Group of the Society of Powder Technology of Japan. Granulation was performed either by agitating granulation, fluidized-bed granulation or extrusion granulation. The dispensing characteristics were comprehensively assessed on the basis of “average weight”, “coefficient of variation”, “weight loss”, and “time for dividing”, as well as “operativeness” based on a sensory test by pharmacists.As the results, it was observed that the dispensing characteristics of fine granules might greatly depend on the granulation method, the amount of binders, the size of bulk materials and the shape of the fine granules. In was also observed that content uniformity of a fine granule, i. e., relationship between its particle size and content, was closely related to the granulation procedure employed.
The systems of insulation and a methodology for assessing the durability (2016)

Formation of effective insulation possible only taking into account features of the insulation layer in the construction and use of high quality materials, preserving their characteristics as in the early stages of operation, and for the entire billing period. The operational stability of the heat-insulating material is determined not only by its properties, but also the ability to withstand long-term operating loads without a significant change in properties. Processing load on the heater may be divided into three groups: the load during transportation and storage, loading and mounting load during operation. Methodology for assessing the properties of insulation products includes two main components: the installation for testing and test methods, as well as the methodology for assessing the operational stability. The methodology of the accelerated testing and forecasting durability tested for mineral wool products laminating, corrugating and volume-oriented structure. The test results give good agreement with the methods recommended by the building codes. Accelerated test plates on the compressibility and compressive strength at 10% deformation after exposure to boiling water over the useful spending for operational control properties of materials, as well as when examining the state of the exploited mineral wool insulation in buildings and heat piping
Un consortium, des consortia (2016)

« Participation, communaute», ce sont par ces mots que debute la definition de « consortium » a la page 406 de l’edition de 1934 du Dictionnaire Latin - Francais de Felix Gaffiot. Ces deux notions peuvent constituer une approche finalement efficace: un consortium est un groupe porte vers l’action. Tenter de caracteriser ce modele d’organisation dans notre milieu professionnel revele l’inscription de nos institutions au sein d’un paysage et d’une communaute documentaires favorables a l’associa...
Abstract 3387: ctDNA dynamics in early stage node negative lung cancers (2023)

Abstract Introduction: Patients with early-stage lung cancers have a high risk of relapse and death even after curative surgery. Detection of circulating tumour DNA (ctDNA) in plasma perioperatively is associated with shorter recurrence free survival (RFS). ctDNA-Lung-Detect is an investigator-initiated prospective study of ctDNA detection and association with RFS in patients with early stage non-small cell lung cancer (NSCLC). Methods: Patients with clinically staged T&amp;lt;4cm N0 NSCLC planned for surgical resection at the Princess Margaret/University Health Network underwent ctDNA assessment before and after surgery (~1 month and 1 year). ctDNA minimal residual disease (MRD) was detected using the highly sensitive and specific tumor-informed Residual Disease and Recurrence (RaDaR®, Inivata, Cambridge, UK) assay, which can track up to 48 tumor-specific variants in plasma. Results: Since August 2021, 64 eligible patients were enrolled (Table 1). One had isolated metastasis from a remote non-lung primary and subsequently excluded; another had their preoperative sample missed but was included. Preoperative ctDNA was detected in 15/62 (23.8%) patients and 1/63 (1.6%) post-operatively at the 1-month landmark timepoint (occult N2 disease found at surgery). All but one (93.3%) had ctDNA clearance with surgical resection. Two patients have recurred radiographically and in plasma at 1 year post-operatively, 1/15 with preoperative ctDNA detected (6.7%) and 1/47 without preoperative ctDNA detected (2.1%). Patients with higher T stage, tumor size, squamous histology, and without actionable driver alterations were more likely to have ctDNA detected at any timepoint. Conclusions: In patients with early stage NSCLC (small node negative tumors), 24% have detectable ctDNA pre-operatively. Surgical resection led to ctDNA clearance in 93% of cases. Our results support ongoing testing beyond the initial MRD landmark. Assessment of the impact on RFS post resection is ongoing. Citation Format: Jamie Feng, Tom Waddell, Kazuhiro Yasufuku, Andrew Pierre, Shaf Keshavjee, Jonathan Yeung, Marcelo Cypel, Laura Donahoe, Elliot Wakeam, Marc de Perrot, Jennifer Law, Alexandra Salvarrey, Lisa W. Le, Jennifer Lister, Michael Cabanero, Ming Tsao, Christodoulos Pipinikas, Karen Howarth, Natasha Leighl. ctDNA dynamics in early stage node negative lung cancers [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 3387.
AppSealer: Automatic Generation of Vulnerability-Specific Patches for Preventing Component Hijacking Attacks in Android Applications (2014)

Component hijacking is a class of vulnerabilities commonly appearing in Android applications. When these vul- nerabilities are triggered by attackers, the vulnerable apps can exfiltrate sensitive information and compromise the data integrity on Android devices, on behalf of the attackers. It is often unrealis- tic to purely rely on developers to fix these vulnerabilities for two reasons: 1) it is a time-consuming process for the developers to confirm each vulnerability and release a patch for it; and 2) the developers may not be experienced enough to properly fix the problem. In this paper, we propose a technique for automatic patch generation. Given a vulnerable Android app (without source code) and a discovered component hijacking vulnerability, we automatically generate a patch to disable this vulnerability. We have implemented a prototype called AppSealer and evaluated its efficacy on apps with component hijacking vulnerabilities. Our evaluation on 16 real-world vulnerable Android apps demon- strates that the generated patches can effectively track and mitigate component hijacking vulnerabilities. Moreover, after going through a series of optimizations, the patch code only represents a small portion (15.9% on average) of the entire program. The runtime overhead introduced by AppSealer is also minimal, merely 2% on average.
Blood Flow Restriction Therapy After Knee Surgery: Indications, Safety Considerations, and Postoperative Protocol (2018)

Blood flow restriction (BFR) training involves occluding venous outflow while maintaining arterial inflow by the application of an extremity tourniquet after surgery. BFR ultimately reduces oxygen delivery to muscle cells, similar to an anaerobic environment, and allows patients to exercise with low resistance and stimulates muscle hypertrophy and strength using heavy resistance. Thus orthopaedic surgeons and physical therapists are incorporating this type of training into their postoperative rehabilitation protocols, particularly after injuries or surgical procedures about the knee joint. The purpose of this Technical Note is to describe a BFR clinical application technique and to report on the indications, safety considerations, and postoperative knee surgery rehabilitation protocols for BFR.
Compact and 10-Gb/s $\times$ 12-Channel Optical Transmitter for Optical Interconnection With High Heat-Dissipation Capability Using Alumina Substrates (2009)

A compact 10-Gb/s times 12-channel optical transmitter was developed for very short-reach optical interconnections. The 10-Gb/s/ch operations were achieved without employing the heat pipes or heat sinks typically required to keep vertical-cavity surface-emitting lasers at a low temperature under 85degC. Alumina ceramic substrates with high heat dissipation capability are incorporated in order to maintain the low temperature operation. The optical transmitter is designed to be as compact as a standard mechanically transferable (MT) optical connector. To enhance usability, the transmitter can be directly connected with the MT-type optical connector with guide pins assembled in the alumina substrate. The compactness and usability of the optical module is effective in intrabox and interbox optical interconnections.
Quantum Field Theory of Inelastic Diffraction. I. Low-Order Perturbation Theory (1971)

Following the definition of the model Hamiltonian, a quantum field theory of inelastic electron scattering from a single-crystal solid is formulated. The interaction of the incident electron with the ion cores is described by the rigid-ion model. The electron-plasmon interaction is described using the random-phase-approximation analysis for jellium. The excitation of both surface and bulk modes is considered explicitly. The electron propagators are renormalized via the electron-electron interactions. Attention is focused on relating diffraction phenomena in the elastic electron-lattice scattering to the differential inelastic cross section. The "surface" conservation laws of energy and momentum parallel to the surface are a consequence of our model of the solid. The vestige of momentum conservation normal to the surface causes a new diffraction phenomenon, "sideband diffraction," in the case of the excitation of a bulkloss mode. This phenomenon should be observable experimentally in the inelastic angular profiles associated with the excitation of bulk plasmons. The general features of both one-step and two-step inelastic diffraction are described in the simplest (kinematical) approximation. The qualitative features associated with the model predictions for the two-step process are in agreement with experimental measurements of differential inelastic cross sections.
ChemInform Abstract: Formal Inverse Sonogashira Reaction: Direct Alkynylation of Arenes and Heterocycles with Alkynyl Halides (2010)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Bone lesions in hairy cell leukemia a case report and response of bone pains to steroids (1984)

An unusual case of hairy cell leukemia is reported. The patient experienced severe bone pains at the sites of the bone lesions caused by infiltration by hairy cells documented histologically. The pains were resistant to various analgesics. Administration of corticosteroids resulted in prompt, full, and sustained response despite the persistence of bone lesions radiographically.
Surgical residents’ opinions on international surgical residency in Flanders, Belgium (2021)

The majority of surgical residents consider an international rotation as educationally beneficial, even though they are rarely undertaken. Our survey shows that in order to facilitate foreign rotations, Flemish universities and governmental institutions will have to alleviate the regulatory, logistical and financial constraints.
Hydrophilus piceus L. (Coleoptera: Hydrophilidae) devouring froglet (1969)

(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Activation of N, P, and A1 in patients and cadavers using radiation from the medical accelerator (1986)

The present work demonstrates that it is possible to monitor the activity of N and P following photoactivation of an anthropomorphic phantom, a patient, and five cadavers. Analysis of the annihilation peak in the spectra revealed the presence of N and P. A strong /sup 28/Al photopeak at 1.78 MeV due to neutron activation was identified in four cadavers and verified according to its half-life (T/sub 1/2/ = 2.30 min). The irradiation of the cadvers in the liver, lung, and skull always yielded the /sup 28/Al photopeak. Any possibility of inducing /sup 28/Al activity through (n,..cap alpha..) reaction of P was excluded. No Al contamination was found in the materials used to preserve the cadaver. The measured spectra with HP-Ge detector provided precision for N of about 2%, and for P 15%. Using NaI detector the precisions improved to 1% and 5% respectively. The quality of the deconvolution was evaluated using the low Chi- squares values, comparing the time integrals with the total number of counts in the peak, and inspection of the residual spectra. 12 refs., 3 figs., 2 tabs.
NO 2 sensitive Au gate metal–oxide–semiconductor capacitors (2001)

Au gate metal-oxide-semiconductor capacitors are sensitive to NO2 in air up to 200 ppm, depending on operating temperature (100 °C to 200 °C), gate thickness (50 to 900 nm), and morphology. In the absence of catalytic properties or lattice diffusivity, a model invoking molecular surface adsorption and grain boundary diffusion is proposed, which quantitatively describes the transient and steady state response of the devices. Sensitivity is given by the arrival of the diffusing species to the gate–dielectric interface, where capacitive coupling of the adsorbed molecules induces work function changes, which shift the flat band voltage positively, opposite that observed for H2 with Pd gates, consistently with an oxidizing, rather than reducing, character.
Hydroxyapatite Nanocrystals as Bone Tissue Substitute (2003)

Abstract The sections in this article are Overview Introduction Biogenic Hydroxyapatite: Bone and Teeth Biomimetic Hydroxyapatite: Porous and Substituted Apatites Biologically Inspired Hydroxyapatite: HA –Collagen Composites and Coatings Functionalized Hydroxyapatite: HA Nanocrystals – Bioactive Molecules Conclusion and Future Challenges Acknowledgments
DECODING COMPLEXITY IN BIOMOLECULAR RECOGNITION OF DNA I-MOTIFS (2023)

DNA i-motifs (iMs) are non-canonical C-rich secondary structures implicated in numerous cellular processes. Though iMs exist throughout the genome, our understanding of iM recognition by proteins or small molecules is limited to a few examples. We designed a DNA microarray containing 10,976 genomic iM sequences to examine the binding profiles of four iM-binding proteins, mitoxantrone, and the iMab antibody. iMab microarray screens demonstrated that pH 6.5, 5% BSA buffer was optimal, and fluorescence was correlated with iM C-tract length. hnRNP K broadly recognizes diverse iM sequences, favoring 3-5 cytosine repeats flanked by thymine-rich loops of 1-3 nucleotides. Array binding mirrored public ChIP-Seq datasets, in which 35% of well-bound array iMs are enriched in hnRNP K peaks. In contrast, other reported iM-binding proteins had weaker binding or preferred G-quadruplex (G4) sequences instead. Mitoxantrone broadly binds both shorter iMs and G4s, consistent with an intercalation mechanism. These results suggest that hnRNP K may play a role in iM-mediated regulation of gene expression <i>in vivo</i>, whereas hnRNP A1 and ASF/SF2 are possibly more selective in their binding preferences. This powerful approach represents the most comprehensive investigation of how biomolecules selectively recognize genomic iMs to date.
Clinical effects of the fetal estrogen estetrol in a multiple-rising-dose study in postmenopausal women (2016)

Estetrol in a dose range of 2-40mg per day improved vaginal cytology and vasomotor symptoms in postmenopausal women. Endometrial proliferation occurred with the 10mg dose. Estetrol seems a safe and suitable candidate to develop further for hormone therapy.
Radiolabeled sucrose covalently linked to protein. A device for quantifying degradation of plasma proteins catabolized by lysosomal mechanisms. (1979)

A general method is described for assessing the degradation of proteins metabolized by lysosomal mechanisms. The method depends on the lysosomal trapping of sucrose which is covalently bound to the protein of interest and thus caried into the lysosome with it. The validity of the method was demonstrated in vitro in studies of the catabolism of low density lipoprotein (LDL) by cultured fibroblasts. Sucrose-derivatized LDL was not distinguished from 125I-LDL by fibroblasts, either in terms of surface binding or rate of uptake. 14C from [14C]sucrose-LDL accumulated in the cells as predicted; very little appeared in the trichloroacetic acid-soluble fraction of the medium (2% of total uptake). 14C-labeled metabolites in the cells (modal apparent Mr = 1000-2000) were separated from undegraded LDL by gel filtration. LDL degradation calculated from the 14C metabolites accumulating intracellularly was in excellent agreement with that calculated from paired studies using 125I-LDL. Finally, the validity of the method was demonstrated in vivo using asialofetuin, a protein previously shown to be selectively taken up and degraded by the liver. In principle, the method described should be applicable to the study of the sites of degradation of any of the plasma proteins.
THE SUN FLAP CLOSURE (2004)

Plastic and Reconstructive Surgery 113(4):p 1288-1289, April 1, 2004. | DOI: 10.1097/01.PRS.0000110801.87800.72
Correction: Hybrid Adeno-Associated Viral Vectors Utilizing Transposase-Mediated Somatic Integration for Stable Transgene Expression in Human Cells (2020)

[This corrects the article DOI: 10.1371/journal.pone.0076771.].
Thermal Synthesis of Silver Nanoplates Revisited: A Modified Photochemical Process (2014)

The well-known photochemical and thermal methods for silver nanoplate synthesis have been generally regarded as two parallel processes without strong connections. Here we report a surprising finding that both visible light and ambient O2, which are critically important in the photochemical process, also play determining roles in the thermal synthesis. By designing a series of control experiments, we reveal that the typical thermal synthesis is essentially a modified photochemical synthesis coupled with the unique redox properties of H2O2. Light irradiation and dissolved O2 are found to be essential for initiating the formation of nanoplates, but the continued growth of nanoplates is supported by the oxidative etching and subsequent reduction of Ag due to H2O2. O2 resulting from the catalytic decomposition of H2O2 etches small nanoparticles to produce Ag(+) ions, which are then reduced back to Ag(0) by anions of H2O2 to support the growth of nanoplate seeds. The involvement of H2O2 in the reaction significantly speeds up the nanoplate formation process. These findings not only greatly improve our understanding of the unique functions of H2O2 in the thermal synthesis, but also bridge the two well established synthesis processes with a unified mechanism, and significantly enhance the reproducibility of the thermal synthesis of Ag nanoplates by identifying the critical importance of ambient light and O2.