gebhart/patrepeval huggingface dataset:
Detection of Serum Antibodies to Psoroptic Mite Antigens in Rabbits Infested with Psoroptes Cuniculi or P. Ovis (Acari: Psoroptidae) by Enzyme-Linked Immunosorbent Assay and Immunodiffusion1 (1983)

Journal Article Detection of Serum Antibodies to Psoroptic Mite Antigens in Rabbits Infested with Psoroptes Cuniculi or P. Ovis (Acari: Psoroptidae) by Enzyme-Linked Immunosorbent Assay and Immunodiffusion Get access William F. Fisher William F. Fisher 2U.S. Livestock Insects Laboratory, ARS, USDA, P.O. Box 232, Kerrville, Texas 78028, USA. Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Medical Entomology, Volume 20, Issue 3, 26 May 1983, Pages 257–262, https://doi.org/10.1093/jmedent/20.3.257 Published: 26 May 1983
GMP Facilities for Manufacturing of Advanced Therapy Medicinal Products for Clinical Trials: An Overview for Clinical Researchers (2010)

To be able to produce advanced therapy medicinal products, compliance with regulatory standards while maintaining flexibility is mandatory. For this purpose, careful planning is vital in the design or upgrade of a facility. Similarly, extensive foresight is elemental to anticipate upcoming needs and requirements. Failing this may lead to the facility's in-ability to meet the demands. In this chapter we aimed to outline the current issues with regards to the European Union Directives (EUD) and the proposal for Advanced Therapies, which are of importance to cellular and gene therapy facilities in Europe. This chapter is an attempt to elucidate what the minimum requirements for GMP facilities for cell and gene therapy products are and what is considered necessary to comply with the regulations in Europe.
Reliability-aware thermal management for hard real-time applications on multi-core processors (2011)

Advances in chip-multiprocessor processing capabilities have led to an increased power consumption and temperature hotspots. Reducing the on-die peak temperature is important from the power reduction and reliability considerations. However, the presence of task deadlines constrain the reduction of peak temperature and thus complicates the determination of optimal speeds for minimizing the peak temperature. We formulate the determination of optimal speeds for minimizing the peak temperature of execution with task deadlines as a quasiconvex optimization problem. This formulation includes accurate power and thermal models with the leakage power dependency on temperature. Experiments demonstrate that our approach is very flexible in adapting to various scenarios of workload and deadline specifications. We obtained an 8°C reduction in peak temperature for a sample execution of benchmarks.
Status of a Tapered Element, Oscillating Microbalance-Based Continuous Respirable Coal Mine Dust Monitor (1996)

Abstract The Mine Safety and Health Administration, Department of Labor, requires coal mine operators to measure compliance with federal respirable dust exposure standards periodically using approved gravimetric samplers. However, the gravimetric approach, with its inherent delays, cannot provide dust concentration data quickly enough to allow on-site correction of inadequate dust control strategies or removal of personnel from harmful environments. Furthermore, alleged tampering with dust samples collected to determine compliance with standards prompted the Secretary of Labor to appoint a special Respirable Dust Task Group to study options to improve monitoring and control of respirable coal mine dust. The Mine Safety and Health Administration's Task Group recommended that the U.S. Bureau of Mines develop a fixed-site monitor that would provide continuous information to the mine worker and mine operator regarding dust levels and the status of compliance with the applicable respirable dust standard. In response to the Mine Safety and Health Administration's request, the U.S. Bureau of Mines is investigating several sensor technologies for continuously monitoring respirable coal mine dust. One of these technologies is the Rupprecht and Patashnick Co. tapered element, oscillating microbalance. The bureau is in the process of investigating the suitability of using this sensor in the high humidity and vibration environment of underground coal mines. Laboratory tests have indicated that, with modification, the sensor can meet the humidity and vibration requirements for underground coal mine use. Currently, the bureau is developing prototypes of a continuous dust monitor based on this technology. When available, these will be evaluated in underground coal mines.
Temperature effects in chromatic confocal distance sensors (2013)

We show, both theoretically and experimentally, the effect of changes in temperature on measurements of distance and displacement by a typical commercial chromatic confocal sensor. A temperature change of even 1°C can lead to an error which is larger than the specified absolute accuracy of the sensor. The dominant factor in this effect is the change of the refractive index of the optics with temperature. A correction procedure is described which yields high accuracy (better than 5 μm) over a temperature range from -5 to 55°C.
Il ruolo primario dell'indennizzo (L. 210/92) per un'adeguata campagna vaccinale in tempo di COVID-19 (2021)

Dall'introduzione della legge 210/92 con la previsione di un indennizzo per lesioni o menomazioni permanenti a seguito di una vaccinazione obbligatoria per legge, la Corte Costituzionale ha ampliato, con specifiche analisi caso per caso e decisioni, anche a eventi avversi derivanti da vaccinazioni soltanto raccomandate, come il vaccino anti-COVID 19. L'Autrice auspica il riconoscimento diretto dell'indennizzo da parte del giudice ordinario competente anche in assenza di pronuncia della Corte Costituzionale, vista l'innegabilità della funzione pubblica e socialmente utile di ogni vaccinazione raccomandata, che velocizzerebbe i tempi di ristoro e conforterebbe la popolazione restia a sottoporsi al vaccino in tempi di pandemia.
ChemInform Abstract: AMINOFUROXANE 1. MITT. SYNTH. UND STRUKTUR (1971)

Abstract Aus den amphi‐Glyoximen (I) können durch Behandlung mit wäßrigem Ammoniak und K‐ferricyanid in einer einzigen Operation die Furoxane (II) (50% Ausbeute) erhalten werden, die sich bei Temperaturen über 80°C quantitativ in die Isomeren (III) umlagern.
A wide-bandwidth W-band LNA in InP/Si BiCMOS technology (2014)

This paper presents the development of high-gain, wide-bandwidth, W-band LNA integrated circuits utilizing a novel 0.25 μm InP/Si BiCMOS process with Ft/Fmax of 330/270 GHz. A 4-stage microstrip LNA achieves a minimum NF of 5.7 dB at 92 GHz and remains less than 7.2 dB (6.4 dB avg.) across a 75-100 GHz bandwidth. The LNA also exhibits a peak gain of 27.7 dB, a 3-dB bandwidth of 18 GHz (80-98 GHz), gain > 20 dB over 75-110 GHz, while consuming only 19.2 mW of DC power from a 1.2V supply. Additionally, individual bias control for each device has been incorporated to vary gain, including a version with two 3-bit current steering DACs to control base currents. The 0.42 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> (w/o pads) LNA is suitable for many emerging W-band applications including radar, communications, and imaging and provides superior performance compared to published LNAs developed in available SiGe BiCMOS technologies.
A Polychromic, Fast Response Metallopolymer Gel Photonic Crystal with Solvent and Redox Tunability: A Step Towards Photonic Ink (P‐Ink) (2003)

A broadly wavelength tunable polyferrocenylsilane–silica composite photonic crystal with a fast response is presented. Polychromic variation in the reflection wavelength is effected via the swelling by solvent of a crosslinked redox‐active metallopolymer gel network incorporated in the voids of a planarized silica colloidal crystal film. The Figure demonstrates the fast mechanical response of the composite photonic crystals.
From "Selena Gomez" to "Marlon Brando" (2015)

Consider a user who submits a search query "Shakira" having a specific search goal in mind (such as her age) but at the same time willing to explore information for other entities related to her, such as comparable singers. In previous work, a system called Spark, was developed to provide such search experience. Given a query submitted to the Yahoo search engine, Spark provides related entity suggestions for the query, exploiting, among else, public knowledge bases from the Semantic Web. We refer to this search scenario as explorative entity search. The effectiveness and efficiency of the approach has been demonstrated in previous work. The way users interact with these related entity suggestions and whether this interaction can be predicted have however not been studied. In this paper, we perform a large-scale analysis into how users interact with the entity results returned by Spark. We characterize the users, queries and sessions that appear to promote an explorative behavior. Based on this analysis, we develop a set of query and user-based features that reflect the click behavior of users and explore their effectiveness in the context of a prediction task.
Enhancing Presence in Head-Mounted Display Environments by Visual Body Feedback Using Head-Mounted Cameras (2009)

A fully-articulated visual representation of a user in an immersive virtual environment (IVE) can enhance the user's subjective sense of feeling present in the virtual world. Usually this requires the user to wear a full-body motion capture suit to track real-world body movements and to map them to a virtual body model. In this paper we present an augmented virtuality approach that allows to incorporate a realistic view of oneself in virtual environments using cameras attached to head mounted displays. The described system can easily be integrated into typical virtual reality setups. Egocentric camera images captured by a video-see-through system are segmented in real-time into foreground, showing parts of the user's body, e. g., her hands or feet, and background. The segmented foreground is then displayed as inset in the user's current view of the virtual world. Thus the user is able to see her physical body in an arbitrary virtual world, including individual characteristics such as skin pigmentation and hairiness.
Elevations of Amniotic Fluid Macrophage Inflammatory Protein-1α Concentrations in Women During Term and Preterm Labor (1996)

Women in labor have significantly elevated AF concentrations of MIP-1 alpha, particularly if labor is associated with intrauterine infection. We suggest that MIP-1 alpha is involved in the physiology of normal labor and in the pathogenesis of infection-associated preterm labor.
Ultrafast Mid-infrared Non-Perturbative Nonlinear Optics in Polycrystalline Zinc Selenide (2018)

Strong-field MIR laser-solid interactions have recently generated great interest. Harmonic continuum was generated in ZnSe with MIR pulses. Power scaling of the harmonics was non-perturbative with conversion efficiency as high as 26%.
A Novel Gene Expression Control System and Its Use in Stable, High-Titer 293 Cell-Based Adeno-Associated Virus Packaging Cell Lines (2002)

Previous attempts to establish 293cell-based stable and high-titer adeno-associated virus (AAV) packaging cell lines were unsuccessful, primarily due to adenovirus E1-activated Rep gene expression, which exerts cytostatic and cytotoxic effects on the host cells. Control of the two large AAV Rep proteins (Rep78/68) was insufficient to eliminate the adverse effects, because of the leaky expression of the two small Rep proteins (Rep52/40). However, it was unsuccessful to control Rep52/40 gene expression since its promoter is located within the coding sequence of Rep78/68. To tightly regulate all four Rep proteins by using their own promoters, we have developed a novel gene control paradigm termed "dual splicing switch," which disrupts all four Rep genes by inserting into their shared coding region an intron that harbors transcription termination sequences flanked the LoxP sites. As a result, the structure and activities of the Rep gene promoters, both p5 and p19, are not affected; however, all of the Rep transcripts are prematurely terminated and the genes were inactivated. Removal of the terminator by Cre protein reactivates the transcription of all four Rep proteins derived from their own promoters. This switch system was initially tested in the lacZ gene and a 600-fold induction of beta-galactosidase activity was observed. Using the dual splicing switch strategy, we have subsequently established a number of AAV packaging cell lines from 293 cells, which showed a normal growth rate, high stability, and more importantly, high yields of AAV vectors. Such a gene control paradigm is also useful for other viruses, e.g., autonomous parvoviruses. Finally, the high-titer 293-based AAV packaging cell lines should greatly reduce the risk of wild-type adenovirus contamination and provide a scalable AAV vector production method for both preclinical and clinical studies.
Technologies toward thermal comfort-based and energy-efficient HVAC systems: A review (2009)

This paper reviews thermal comfort based control strategies for modern commercial buildings with heating, ventilating, and air-conditioning (HVAC) systems. In order to make HVAC systems more energy-efficient, better system operations and control algorithms for HVAC systems are demanded. Research conducted predominately within the last decade suggests that commercial building HVAC significantly influences the health, satisfaction, and productivity of the building occupants. This paper also projects the use of wireless sensor networks (WSNs) to enhance energy efficiency of HVAC systems as well as provides comfortable environment to assure occupants' productivities.
The current and future therapy of allergic conjunctivitis (1998)

A wealth of antiallergic drugs is available for ocular allergy, and many new drugs will soon be approved. Pharmaceutical companies frequently seek approval of anti-inflammatory drugs for allergic indications, because it is relatively easy to perform clinical trials for ocular allergy. Extremely safe drugs for mild to moderate degrees of allergic conjunctivitis include antihistamines, mast cell stabilizers, and nonsteroidal anti-inflammatory agents. Topical corticosteroids, preferably those with reduced side effects, are available for more severe forms of ocular allergy. The choice of an antiallergic drug may be guided by the indication for which the drug was approved. The ultimate selection will be made based on the patient's symptoms, the drug's availability, and its cost.
Cycloaddition Reactions of a Chromium–Chromium Quintuple Bond (2011)

Give me five! Addition of alkynes as well as dienes to a quintuply bonded dichromium complex was investigated and cycloaddition reactions were observed (see scheme). The structures of the obtained compounds indicate the reduction of the alkyne and diene ligands, an oxidation of the chromium atoms, as well as the decrease of the CrCr bond order. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Splitting Convolutional Neural Network Structures for Efficient\n Inference (2020)

For convolutional neural networks (CNNs) that have a large volume of input\ndata, memory management becomes a major concern. Memory cost reduction can be\nan effective way to deal with these problems that can be realized through\ndifferent techniques such as feature map pruning, input data splitting, etc.\nAmong various methods existing in this area of research, splitting the network\nstructure is an interesting research field, and there are a few works done in\nthis area. In this study, the problem of reducing memory utilization using\nnetwork structure splitting is addressed. A new technique is proposed to split\nthe network structure into small parts that consume lower memory than the\noriginal network. The split parts can be processed almost separately, which\nprovides an essential role for better memory management. The split approach has\nbeen tested on two well-known network structures of VGG16 and ResNet18 for the\nclassification of CIFAR10 images. Simulation results show that the splitting\nmethod reduces both the number of computational operations as well as the\namount of memory consumption.\n
Current strategies and challenges for the purification of stem cells (2011)

Abstract During the past decade, stem cell transplant has emerged as a novel therapeutic alternative for several diseases. If therapies are to be implemented in clinical settings, efficient scale‐up of stem cells isolation methodologies would be crucial. A brief, process‐oriented overview of the current most widely used technologies for stem cells separation is presented. This review classifies available methods into three broad categories: (1) isopycnic centrifugation, including density gradient and cell culture; (2) immunochemical, employing immune labeling; and (3) novel, tagless procedures. These groups are further subdivided into more specific techniques, highlighting their advantages and limitations. Particular cases in each category were selected to further compare the purification parameters of recovery, cell viability, purity, process time, and throughput. A particular focus on process scale‐up feasibility and the challenges of this rapidly emerging field are stated. Lastly, likely directions are suggested for the development of new proposals which will make stem cells purification more advantageous and viable for clinical use. Copyright © 2011 Society of Chemical Industry
Clot busters! Relief of gastric outlet obstruction after Roux-en-Y gastric bypass (2014)

Roux-en-Y gastric bypass (RYGB) is a highly effective surgical approach for the treatment of morbid obesity [1]. Postsurgical bleeding leading to intraluminal blood clot formation causes gastric outlet obstruction (GOO) at the site of the anastomosis, and is typically managed by laparotomy or surgical revision [1] [2]. Gastrojejunal clots causing GOO following laparoscopic RYGB occur in 3 % – 27 % of patients [2]. Endoscopic dilation of gastrojejunal obstruction provides an alternative to surgical revision, but symptomatic relief may require up to three dilations [3] [4]. We present a case series of three patients who developed intraluminal blood clots at the gastrojejunal anastomosis (GJA) within 72 hours of robotically assisted RYGB surgery.
Comparison of the Kato-Katz thick smear and McMaster egg counting techniques for monitoring drug efficacy against soil-transmitted helminths in schoolchildren on Pemba Island, Tanzania (2012)

The Kato-Katz thick smear technique is widely used to assess prevalence and intensity in soil-transmitted helminth (STH) control programmes, but its usefulness in monitoring anthelminthic drug efficacy needs to be validated and compared with other methods. A promising alternative is the McMaster egg counting technique. In the present study, the efficacy of single-dose albendazole against STH infections in 430 schoolchildren on Pemba Island was assessed using both the Kato-Katz and McMaster techniques. The study revealed comparable drug efficacy results for both methods and confirmed the potency of the McMaster technique as an alternative method for monitoring large-scale deworming programmes.
Nanotubular non-covalent macrocycle within non-covalent macrocycle assembly: (MeOH)12 encapsulated in a molecular clip cyclododecamer (2010)

A noncovalent macrocycle-within-noncovalent macrocycle assembly is formed from twelve molecules of (+/-)-1 and twelve molecules of MeOH in the solid state. The H-bonded (MeOH)(12) cyclododecamer assumes a crown-shaped geometry that has not previously been predicted theoretically or found experimentally.
A microprocessor-controlled speed regulator with instantaneous speed estimation for motor drives (1988)

A method for estimating instantaneous speed, suited for a microprocessor-based speed regulator for motor drives, and the characteristics of the speed control system are described. Features of the proposed method include the estimation of instantaneous speed at a real-time point using values of average speed detected by counting for a certain time the output pulses of an encoder as well as the estimated value as the speed feedback signal for the speed regulator. Since this method allows compensation to be made for the lag time of the feedback signal caused by detection of the mean value, it contributes to improved stability of the speed regulator. In particular, this provides a significant suppression of the vibrations that are generated in motor-driven machinery.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Ablation of Complex Fractionated Atrial Electrograms in Catheter Ablation for AF; Where have we been and where are we going? (2012)

Catheter ablation for persistent AF remains a challenge to the ablator as the disease is now outside the veins and cannot be tackled by pulmonary vein isolation alone. In this article we describe targeting complex fractionated atrial electrograms (CFAE) as a method to guide atrial substrate modification.
Classification of the acoustic environments using a psychoacoustic model (1999)

Complex digital hearing aid algorithms employ different signal processing stages, e.g., noise reduction and loudness control. Most of these stages are suitable only for special acoustic environments or need different parameter sets for different environments to assure optimum rehabilitation success. Future ‘‘intelligent’’ digital hearing aids should therefore incorporate a model of the acoustic environment to adapt the signal processing to the acoustic environment. In particular, the presence of a speech signal and of different types of ambient noise should be detectable. In this study, the perception model introduced by Dau et al. [J. Acoust. Soc. Am. 102, 2829–2919 (1996)], which was originally developed to model different psychoacoustical tasks, e.g., forward masking and modulation detection is used as a preprocessor for this type of classification algorithms. This approach seems promising, as the model includes a modulation frequency analysis which was shown to be a good estimator of speech activity [Ostendorf, Fortschritte der Akustik DAGA 98, Zürich]. First results on the classification accuracy using this model are presented.
Anti-idiotypic induced suppression of Sjögren's syndrome associated anti-La autoantibody secretion in vitro. (1988)

Peripheral blood mononuclear cells from patients with Sjögren's Syndrome spontaneously secrete autoantibodies to the La antigen when cultured in vitro. This paper reports that specific IgG autoantibody production in vitro is suppressed by pre-treatment of CD8+ enriched T cells with rabbit polyclonal antibodies to idiotypes borne by circulating autologous anti-La antibodies. Treatment of this T cell subpopulation with anti-idiotypes specific for circulating anti-La antibodies from other patients or for anti-DNA antibodies was without effect on anti-La antibody production. Similarly anti-La anti-idiotypes had no effect on the production of autoantibodies to other ribonucleoprotein antigens such as nRNP/Sm. These data show that CD8+ T cells are the main targets for anti-idiotypic control in vitro. We suggest that the relative deficit of these cells, plus a surfeit of CD4+ T cells at the site of the pathological lesion within the salivary gland permits localized production of autoantibodies. Thus, dysregulation of the idiotypic network could contribute to the pathogenesis of Sjögren's Syndrome.