gebhart/patrepeval huggingface dataset:
A Search for Tritium Production in Electrolytically Deuterided Palladium (1991)

A search for anomalous heat generation and tritium production that could be associated with cold fusion in electrolytically deuterided palladium was carried out for > 180 days. Ten cathodes were mounted in electrolytic cells with LiOD and LiOH electrolytes and galvanostatically charged at current densities between 15 and 348 mA/cm2. Most of the electrolytic cells were closed to the external environment; in all cells, the gases evolved during electrolysis were internally recombined using platinum recombination catalysts mounted in the cells. Tritium concentration assays using a liquid scintillation analyzer were performed on aliquots of electrolyte taken from some cells. No increase in tritium concentration was observed in the closed cells; in the partially open cells, small fluctuations in tritium concentration were observed, but these can be attributed to systematic errors.
The role of MucodyneR in reducing the need for surgery in patients with persistent otitis media with effusion (2000)

operative intervention or not. Of the 28 patients with resolved OME, 17 were in the Mucodyne group and 11 in the placebo group. Although it appeared that patients treated with Mucodyne were 1.68 times more likely to undergo resolution of OME than patients receiving placebo, this did not reach statistical significance. [Risk ratio of 1.68 (95% C.I., 0.74-3.37)]. chi2 test (df = 162) = 2.24 (P = 0.134). The absolute risk difference in the study was 8.5% (95% C.I., -3-20). We cannot exclude the possibility that Mucodyne is as beneficial as a 20% additional resolution of OME, or as harmful as a 3% decrease in the resolution of OME.
Estados Unidos e o Direito Internacional dos Conflitos Armados: a negação da herança de Lieber (2004)

Partindo-se das influencias do denominado “Código Lieber”, o presente artigo analisa a atual situação dos Estados Unidos, no que se refere ao direito internacional.
Analyzing cache performance for video servers (2002)

Video on demand (VOD) is expected to become one of the most important and successful services to be offered on emerging technologies. There is not just an interest in the delivery of digital video for home entertainment purposes, but there are also several educational and commercial benefits from this service. However, for this service to become viable, it is important that the video servers meet the demanding data rates and real time performance requirements imposed by video. Interval caching has been proposed as a cost effective way of improving the throughput of a server, but all previous studies on interval caching have used simulation. With numerous parameters and their complex interplay affecting the performance of interval caching, it is infeasible to consider a full factorial experiment with simulation. The paper presents an analytical model for interval caching on video servers. The model has been extensively validated over a range of client requests, video data and server parameters. In addition, the model has been generalized to accommodate variable lengths of video data stored at the server. Using this model, the impact of different parameters has been studied on the performance of interval caching scheme.
Defective Translocation of PKCε in EtOH‐Induced Inhibition of Mg2+ Accumulation in Rat Hepatocytes (2010)

Translocation of PKCepsilon isoform to the hepatocyte membrane is essential for Mg(2+) accumulation to occur. Both acute and chronic ethanol administrations inhibit Mg(2+) accumulation by specifically altering PKCepsilon translocation to the cell membrane.
Effect of Chronic Restraint Stress on Human Colorectal Carcinoma Growth in Mice (2013)

Stress alters immunological and neuroendocrinological functions. An increasing number of studies indicate that chronic stress can accelerate tumor growth, but its role in colorectal carcinoma (CRC) progression is not well understood. The aim of this study is to investigate the effects of chronic restraint stress (CRS) on CRC cell growth in nude mice and the possible underlying mechanisms. In this study, we showed that CRS increased the levels of plasma catecholamines including epinephrine (E) and norepinephrine (NE), and stimulated the growth of CRC cell-derived tumors in vivo. Treatment with the adrenoceptor (AR) antagonists phentolamine (PHE, α-AR antagonist) and propranolol (PRO, β-AR antagonist) significantly inhibited the CRS-enhanced CRC cell growth in nude mice. In addition, the stress hormones E and NE remarkably enhanced CRC cell proliferation and viability in culture, as well as tumor growth in vivo. These effects were antagonized by the AR antagonists PHE and PRO, indicating that the stress hormone-induced CRC cell proliferation is AR dependent. We also observed that the β-AR antagonists atenolol (ATE, β1- AR antagonist) and ICI 118,551 (ICI, β2- AR antagonist) inhibited tumor cell proliferation and decreased the stress hormone-induced phosphorylation of extracellular signal-regulated kinases-1/2 (ERK1/2) in vitro and in vivo. The ERK1/2 inhibitor U0126 also blocked the function of the stress hormone, suggesting the involvement of ERK1/2 in the tumor-promoting effect of CRS. We conclude that CRS promotes CRC xenograft tumor growth in nude mice by stimulating CRC cell proliferation through the AR signaling-dependent activation of ERK1/2.
Mathematical Modeling and Simulation of Bubble Column Reactor for Aerial Liquid Phase Cyclohexane Oxidation (2010)

Cyclohexane oxidation is an important but complex commercial reaction, wherein the desired product, K‐A oil appears as an intermediates of the reaction sequence. A mathematical model has been developed for the bubble column reactor operating under isothermal conditions. The mass and energy model equations consisted of stiff ODEs. The model was applied to describe the behavior of bubble column reactor for aerial liquid phase cyclohexane oxidation. Effect of initial substrate concentration, catalyst loading and temperature was studied and discussed in detail. Conclusions were presented at the end of the study.
Elevation of fumarase attenuates hypertension and can result from a nonsynonymous sequence variation or increased expression depending on rat strain (2017)

The activity of fumarase, an enzyme in the tricarboxylic acid cycle, is lower in Dahl salt-sensitive SS rats compared with SS.13<sup>BN</sup> rats. SS.13<sup>BN</sup> rats have a Brown Norway (BN) allele of fumarase and exhibit attenuated hypertension. The SS allele of fumarase differs from the BN allele by a K481E sequence variation. It remains unknown whether higher fumarase activities can attenuate hypertension and whether the mechanism is relevant without the K481E variation. We developed SS-TgFh1 transgenic rats overexpressing fumarase on the background of the SS rat. Hypertension was attenuated in SS-TgFh1 rats. Mean arterial pressure in SS-TgFh1 rats was 20 mmHg lower than transgene-negative SS littermates after 12 days on a 4% NaCl diet. Fumarase overexpression decreased H<sub>2</sub>O<sub>2</sub>, while fumarase knockdown increased H<sub>2</sub>O<sub>2</sub> Ectopically expressed BN form of fumarase had higher specific activity than the SS form. However, sequencing of more than a dozen rat strains indicated most rat strains including salt-insensitive Sprague-Dawley (SD) rats had the SS allele of fumarase. Despite that, total fumarase enzyme activity in the renal medulla was still higher in SD rats than in SS rats, which was associated with higher expression of fumarase in SD. H<sub>2</sub>O<sub>2</sub> can suppress the expression of fumarase. Renal medullary interstitial administration of fumarase siRNA in SD rats resulted in higher blood pressure on the high-salt diet. These findings indicate elevation of total fumarase activity attenuates the development of hypertension and can result from a nonsynonymous sequence variation in some rat strains and higher expression in other rat strains.
From Reactive Latexes to Core-Shell Polymer Nanoparticles for Functional Water-Borne Coatings: Surface Characterization and Stability (2007)

Polymeric hybrid materials have recently attracted great interest due to their advantageous\nperformance relative to the non-hybrid counterparts. Typical hybrid materials contain a compact\ninorganic phase bonded (often covalently) with an organic phase, which may be phase-segregated or\ndispersed at a molecular level. Recently, hybrids containing polyhedral oligosilsesquioxanes (POSS)\neither covalently bonded to or simply dispersed in the polymer matrix have been the subject of\nincreasing attention. This is due to the potentially interesting properties associated with the unique\nstructure of the POSS cage, a nanoparticle with silica-like inorganic core (SiO1.5)n (n = 8, 10, 12) and\nan outer shell of covalently bonded hydrocarbon or organofunctional groups. These organophilic\nPOSS derivatives can be incorporated into virtually any polymer and, depending on the specific\npolymer-POSS interaction, provide the polymer matrix with enhanced or new application properties.\nCopolymerization of monofunctional or multifunctional POSS derivatives is an effective way of\nachieving a good dispersion of the POSS moieties, and a wide variety of synthetic routes have been\nproposed, mainly based on solution or melt processing. On the other hand, the synthesis of POSScontaining\ncopolymers by hetherophasic polymerization has received much less attention.\nWe had previously described the first example of the synthesis of hybrid POSS-acrylic copolymer\nlatexes by miniemulsion polymerization.1 In the present investigation the thermal, mechanical and\nsurface properties of the nanocomposite latex films at increasing POSS loadings have been evaluated.\nSemi-IPN structures were also produced by photopolymerization of monomer-swollen latex films as a\nmeans to further investigate the microgel structure and mechanical properties of the material.
First-line paclitaxel and cisplatin in patients with advanced squamous-cell carcinoma of the esophagus (2007)

15157 Objectives: To evaluate response rate, survival and toxicities of paclitaxel/cisplatin combination in patients with advanced or metastatic squamous-cell carcinoma of the esophagus. Methods: Thirty-nine patients with definite measurable indices and no prior chemotherapy were enrolled. Patients were treated with paclitaxel 175 mg/m 2 by 2-hour infusion day 1 and cisplatin 75 mg/m 2 infusion day 1. Treatment was repeated every 21 days. Results: Thirty-nine patients were enrolled. 35 patients were eligible to be evaluated for response. The overall response rate was 48.6% (95% confidence interval [CI], 0.31∼0.65) with complete and partial response rates of 2.8% and 45.7%, respectively. The median time to progression(TTP) was 7 months, and median survival time of all patients was 13 months. There was a significant difference in median overall survival between the patients who had received responding versus those who had not (p = 0.006). Median survival was 17 (95% CI, 11.9–22.0) and 10 months (95% CI, 7.6–12.35) for responding patients and non-responding patients, respectively. The 1-yr survival probability was 39%. Relief of dysphagia and pain were observed in 86.2% of the all patients. The most common toxicities were neutropenia and alopecia. There were no grade 4 clinical toxicities and treatment-related deaths were recorded in all patients. Conclusions: Paclitaxel and cisplatin is a promising treatment for patients with squamous-cell carcinoma of the esophagus. The toxicity of this regimen is within acceptable range. No significant financial relationships to disclose.
Rapid method for the purification of bovine thrombin and the inhibition of the purified enzyme with phenylmethylsulfonyl fluoride (1971)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRapid method for the purification of bovine thrombin and the inhibition of the purified enzyme with phenylmethylsulfonyl fluorideRoger L. LundbladCite this: Biochemistry 1971, 10, 13, 2501–2506Publication Date (Print):June 1, 1971Publication History Published online1 May 2002Published inissue 1 June 1971https://pubs.acs.org/doi/10.1021/bi00789a012https://doi.org/10.1021/bi00789a012research-articleACS PublicationsRequest reuse permissionsArticle Views366Altmetric-Citations223LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Compression Performances of Computer Vision Based Coding (2004)

This paper presents new results in the field of very low bitrate codir~g and cornpression usirig 3D iriforrnations. Contrary to prior art in model-based coding where 3D models have to be known, the 3D models are automatically computed from the original video sequence. The camera parameters and the scene content are supposed unknown and the video sequence is processed on the fly. A stream of 3D models is then extracted and compressed, using adapted compression techniques. \Ve finally show results of the proposed compression scheme, and show the efficiency of these approach.
DPC materials and corrosion environments. (2014)

After an exposition of the materials used in DPCs and the factors controlling material corrosion in disposal environments, a survey is given of the corrosion rates, mechanisms, and products for commonly used stainless steels. Research needs are then identified for predicting stability of DPC materials in disposal environments. Stainless steel corrosion rates may be low enough to sustain DPC basket structural integrity for performance periods of as long as 10,000 years, especially in reducing conditions. Uncertainties include basket component design, disposal environment conditions, and the in-package chemical environment including any localized effects from radiolysis. Prospective disposal overpack materials exist for most disposal environments, including both corrosion allowance and corrosion resistant materials. Whereas the behavior of corrosion allowance materials is understood for a wide range of corrosion environments, demonstrating corrosion resistance could be more technically challenging and require environment-specific testing. A preliminary screening of the existing inventory of DPCs and other types of canisters is described, according to the type of closure, whether they can be readily transported, and what types of materials are used in basket construction.
Compaction of Metal-Ceramic Powder Mixtures. Part.2 (2017)

In the second part of paper are presented the old and new compression equations that describe the densification mechanism of one phase (metal/ceramic) powders or two-phase metal-ceramic powders during compaction and also the effect of ceramic particles additions in metallic matrix quantified by densification equations or compaction models. We studied the applicability of compaction models on different metal-ceramic powder mixtures for better understanding the possibilities and limitations of metal-ceramic powder compaction.
Consecuencias éticas del naturalismo deweyano (1992)

Two naturally occurring tropane alkaloids, anisodamine and scopolamine, structurally dissimilar in one OH group, are well established as muscarinic acetylcholine receptor (mAChR) antagonists in clinic and basic research. However, experimental evidence for central effects of anisodamine is limited and conflicting compared with that of scopolamine. In the present study, Morris water maze test, long-term potentiation (LTP) recording and receptor radioligand binding assays were used to explore the disparity in neuropsychopharmacological influences of anisodamine versus scopolamine and possible mechanisms. Anisodamine, at 10-40-fold higher doses than those of scopolamine, did not produce any spatial cognitive deficits as scopolamine, but tended to improve cognition at the repeated high doses. LTP in vivo was then adopted to predict BBB permeability of the muscarinic antagonists following systemic drug administration. Contrary to scopolamine, anisodamine did not influence the formation of LTP in the CA(1) region of rat hippocampus at 40-fold higher dose than that of scopolamine. Additionally, receptor radioligand binding assays (RRLBA) revealed that the binding affinity of anisodamine to mice brain mAChR was much lower than that of scopolamine. The findings suggested that anisodamine did not impair cognition nor depress LTP primarily due to its poor BBB permeability. This work enlarged knowledge of structure-activity relationship among tropane alkaloids, meanwhile providing evidence for more reasonable drug prescription in clinic.
A survey and taxonomy of distributed certificate authorities in mobile ad hoc networks (2011)

Certificate authorities (CAs) are the main components of PKI that enable us for providing basic security services in wired networks and Internet. But, we cannot use centralized CAs, in mobile ad hoc networks (MANETs). So, many efforts have been made to adapt CA to the special characteristics of MANETs and new concepts such as distributed CAs (DCAs) have been proposed that distribute the functionality of CA between MANET nodes. In this article, we study various proposed DCA schemes for MANET and then classify these schemes according to their internal structures and techniques. Finally, we propose the characteristics of an ideal DCA system that can be used to verify the completeness of any DCA scheme. This classification and taxonomy identify the weakness and constraints of each scheme, and are very important for designing more secure, scalable, and high performance DCA systems for MANETs and other networks.
Robust Self-Calibrating nCPMG Acquisition: Application to Body Diffusion-Weighted Imaging (2017)

This paper demonstrates a robust diffusion-weighted single-shot fast spin echo (SS-FSE) sequence in the presence of significant off-resonance, which includes a variable-density acquisition and a self-calibrated reconstruction as improvements. A non-Carr-Purcell-Meiboom-Gill (nCPMG) SS-FSE acquisition stabilizes both the main and parasitic echo families for each echo. This preserves both the in-phase and quadrature components of the magnetization throughout the echo train. However, nCPMG SS-FSE also promotes aliasing of the quadrature component, which complicates reconstruction. A new acquisition and reconstruction approach is presented here, where the field-of-view is effectively doubled, but a partial k-space and variable density sampling is used to improve scan efficiency. The technique is presented in phantom scans to validate SNR and robustness against rapidly varying object phase. In vivo healthy volunteer examples and the clinical cases are demonstrated in abdominal imaging. This new approach provides comparable SNR to previous nCPMG acquisition techniques as well as providing more uniform apparent diffusion coefficient maps in phantom scans. In vivo scans suggest that this method is more robust against motion than previous approaches. The proposed reconstruction is an improvement to the nCPMG sequence as it is auto-calibrating and is justified to accurately treat the signal model for the nCPMG SS-FSE sequence.
Compositional Analysis of a Terpolymer Photoresist by Raman Spectroscopy (1982)

The trend towards miniaturization in microstructure fabrication has created a demand for improved methods of production. The preceding paper (1) detailed one of the areas of research in this area, development of a deep UV-degradable photo-resist and presented a likely candidate, poly(methyl methacrylate-co-3- oximino-2-butanone methacrylate-co-methacrylonitrile) (P(M-OM-CN)). While all of the results to date are encouraging, the exact composition of the terpolymer samples tested has been unknown. That information should be obtained in order to take full advantage of this resist. These polymers are especially resistant to the standard methods of analysis. Elemental analysis can be plagued by inaccuracies that arise from difficulties in determining low percentages of nitrogen and from residual solvent or monomers present in the polymers. UV spectrophotometry is useless because only the 3-oximino-2-butanone moiety yields a distinct UV spectrum. Pmr (proton magnetic resonance) spectroscopy has problems with overlapping absorptions. Only methyl methacrylate and the α-keto-oxime
Evidence for postmeiotic genetic activity in pollen of Cucurbita species (1979)

Investigation of postmeiotic expression of genes in pollen has been complicated by the reduced size and morphology of this developmental stage. This has necessitated the application of either colorimetric tests to pollen physiology or polygenic analyses of pollen tube growth rates.The first of these is of limited applicability and the second is cumbersome. In the present paper we demonstrate the application of microelectrophoresis to single pollen grains of Cucurbita species, thus providing direct examination of gametophytic gene products. The system promises to be of relatively widespread applicability and is technically straightforward.
Deep beamforming networks for multi-channel speech recognition (2016)

Despite the significant progress in speech recognition enabled by deep neural networks, poor performance persists in some scenarios. In this work, we focus on far-field speech recognition which remains challenging due to high levels of noise and reverberation in the captured speech signals. We propose to represent the stages of acoustic processing including beamforming, feature extraction, and acoustic modeling, as three components of a single unified computational network. The parameters of a frequency-domain beam-former are first estimated by a network based on features derived from the microphone channels. These filter coefficients are then applied to the array signals to form an enhanced signal. Conventional features are then extracted from this signal and passed to a second network that performs acoustic modeling for classification. The parameters of both the beamforming and acoustic modeling networks are trained jointly using back-propagation with a common cross-entropy objective function. In experiments on the AMI meeting corpus, we observed improvements by pre-training each sub-network with a network-specific objective function before joint training of both networks. The proposed method obtained a 3.2% absolute word error rate reduction compared to a conventional pipeline of independent processing stages.