gebhart/patrepeval huggingface dataset:
AED-Net: An Abnormal Event Detection Network (2019)

It has long been a challenging task to detect an anomaly in a crowded scene. In this paper, a self-supervised framework called the abnormal event detection network (AED-Net), which is composed of a principal component analysis network (PCAnet) and kernel principal component analysis (kPCA), is proposed to address this problem. Using surveillance video sequences of different scenes as raw data, the PCAnet is trained to extract high-level semantics of the crowd’s situation. Next, kPCA, a one-class classifier, is trained to identify anomalies within the scene. In contrast to some prevailing deep learning methods, this framework is completely self-supervised because it utilizes only video sequences of a normal situation. Experiments in global and local abnormal event detection are carried out on Monitoring Human Activity dataset from University of Minnesota (UMN dataset) and Anomaly Detection dataset from University of California, San Diego (UCSD dataset), and competitive results that yield a better equal error rate (EER) and area under curve (AUC) than other state-of-the-art methods are observed. Furthermore, by adding a local response normalization (LRN) layer, we propose an improvement to the original AED-Net. The results demonstrate that this proposed version performs better by promoting the framework’s generalization capacity.
ChemInform Abstract: A New and Versatile Diamide—Diamine Donor Ligand Set in Early Transition Metal Chemistry. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Performance and Safety Characteristics of Sanyo NiCd Cells (2002)

NiCd batteries are widely used for high drain applications like power tools and also in other portable equipment like cameras, PCs, etc. NASA and Dreamtime Holdings, Inc. worked together to have the capability of a High Definition TV (HDTV) on the ISS and Space Shuttle. The Sanyo HD camcorder was used on the STS 105 fight in July, 2001 . The camcorder used two versions of a NiCd battery. One was a cOlnmercial off-the-shelf Sony BP90 battery pack that had Sanyo NiCd D cells. The other was a modified battery (FBP-90) made by Frezzi Energy, which also had the same Sanyo NiCd D cells. The battery has 10 NiCd D cells in series to form a 12 V pack with 5.0 Ah capacity. Our current study involved the perforn1ance and abuse tests on the Sanyo NiCd 5.0 Ah D cells. The best combination of charge/discharge current rate is 0.3C for charge and 1/2e for discharge within 200 cycles. No significant changes in capacity were observed in 200 cycles. The cell also showed capability of 5C (25.0A) high rate discharge. In overcharge and overdischarge tests, all tested cells passed the tests without venting. In imbalance tests, the battery pack could be charged and discharged only at relatively low current. At charge current of 1.0A or less, the imbalanced cells in the battery pack displayed relatively high temperatures during charge or discharge. The cells functioned normally during internal short and no mishap occurred during external short. Cells passed exposure tests at 80 C and no leakage till 150 C during heat-tovent tests.
Artificial Cell Therapy: New Strategies for the Therapeutic Delivery of Live Bacteria (2005)

There has been rapid growth in research regarding the use of live bacterial cells for therapeutic purposes. The recognition that these cells can be genetically engineered to synthesize products that have therapeutic potential has generated considerable interest and excitement among clinicians and health professionals. It is expected that a wide range of disease modifying substrates such as enzymes, hormones, antibodies, vaccines, and other genetic products will be used successfully and will impact upon health care substantially. However, a major limitation in the use of these bacterial cells is the complexity of delivering them to the correct target tissues. Oral delivery of live cells, lyophilized cells, and immobilized cells has been attempted but with limited success. Primarily, this is because bacterial cells are incapable of surviving passage through the gastrointestinal tract. In many occasions, when given orally, these cells have been found to provoke immunogenic responses that are undesirable. Recent studies show that these problems can be overcome by delivering live bacterial cells, such as genetically engineered cells, using artificial cell microcapsules. This review summarizes recent advances in the therapeutic use of live bacterial cells for therapy, discusses the principles of using artificial cells for the oral delivery of bacterial cells, outlines methods for preparing suitable artificial cells for this purpose, addresses potentials and limitations for their application in therapy, and provides insight for the future direction of this emergent and highly prospective technology.
Abstract 17900: A Common Single Nucleotide Polymorphism Associated With Atrial Fibrillation Modulates Symptomatic Response To Antiarrhythmic Drug Therapy (2010)

Introduction: Recent genome wide association studies have identified 3 loci, on chromosomes 4q25 (near PITX2), 16q22 (in ZFHX3), and 1q21 (in KCNN3), that associate with either typical or lone atri...
Aerodynamic effects of compressibility for wind turbines at high tip speeds (2018)

In the present work two dimensional airfoil computations are used to investigate the effects of compressibility in the tip region of large scale wind turbines of 20 MW+ size. In the past application of incompressible CFD solvers have been wide spread for wind turbine aerodynamics, due to their efficiency and robustness at the near incompressible conditions experienced near the rotor center. With the increasing size of modern wind turbines and the desire to approach high tip speeds, the incompressible assumption might be violated in the tip region of the turbine. To investigate the effects of compressibility and the possibility of correcting incompressible flow solutions using explicit compressibility corrections, a CFD study of 2D airfoil aerodynamics at conditions of a large scale wind turbine is performed. The present study show that classical compressibility corrections can be successfully applied as a post-processing step to incompressible solutions, reducing the error in the predicted lift and drag to within a few percent for attached flow conditions where viscous effects are limited at Mach numbers upto 0.3.
Differentially Expressed Proteins of Mesenchymal Stem Cells Derived from Human Cord Blood (hUCB) during Osteogenic Differentiation (2008)

Multipotent mesenchymal stem cells (MSCs) derived from human umbilical cord blood (hUCB) represent promising candidates for the development of future cellular therapy strategies. MSCs have been found to be able to differentiate into various tissues. One of the primary limitations in our understanding of the biology of human MSCs is the absence of prospective markers required for the monitoring of lineage-specific differentiation. hUCB-derived MSCs have been found to have significantly greater osteogenic potential. In this study, we focused on proteins that were differentially expressed during osteogenic differentiation of hUCB-MSCs. And we analyzed the protein expression inherent to osteogenic differentiation by two-dimensional gel electrophoresis, ESI-Q-TOF, and Western blotting. Eleven differentially expressed spots were observed between the two groups (before and after differentiation) on the 2-DE map. These might also be proved as useful cytosolic biomarker proteins for osteogenesis, and might be employed in quality control of osteoblasts in cell-therapy applications.
Stability of Hingeless Rotors in Hover Using Three‐Dimensional Unsteady Aerodynamics (1991)

U.S. Army Research Office as part of the Center of Excellence in Rotary Wing Aircraft Technology, contranct numbers DAAG29-82-K-0094 and DAAL3-88-C-0003, monitored by Dr. Robert Singlcton.
A Parallel-Data-Free Speech Enhancement Method Using Multi-Objective Learning Cycle-Consistent Generative Adversarial Network (2020)

Recently, deep neural networks (DNNs) have become the mainstream strategy for speech enhancement task because it can achieve the higher speech quality and intelligibility than the traditional methods. However, these DNN-based methods always need a large number of parallel corpus consisting of clean speech and noise to produce noisy data for the training of the DNN in order to improve the generalization of the network. As a result, this implies that many noisy speech signals that are collected in real environment cannot be used to train the DNN because of the lack of corresponding clean speech and noise. Additionally, as we know, noise varies with the time and scenario, so we cannot obtain parallel speech and noise due to infinite noise data and some limited speech data. Thus, the network training with unparallel speech and noise data is essential for the generalization of the network. To address this problem, we propose a novel parallel-data-free speech enhancement method, in which the cycle-consistent generative adversarial network (CycleGAN) and multi-objective learning are employed. Our method is also able to make best use of the benefits of multi-objective learning. On the training stage, we utilize two different encoders to encode the features of clean speech and noisy speech, respectively. Then, two forward generators are immediately used to predict the ideal time-frequency (T-F) mask and log-power spectrum (LPS) of clean speech. Two inverse generators are applied to map the magnitude spectrum (MS) and LPS of noisy speech, respectively. In addition, four discriminators are used to distinguish the real speech features from the generated features. Two encoders, four generators and four discriminators are simultaneously trained by using adversarial, identity-mapping, latent similarity and cycle-consistent loss. On the test stage, we directly utilize the forward generators and encoders to acquire the enhanced speech. The experimental results indicate that the proposed approach is able to achieve the better speech enhancement performance than the reference methods. Moreover, the proposed method is also effective to improve speech quality and intelligibility when the networks are trained under the parallel data.
Selective Optical Imaging for Detection of Bacterial Biofilms in Tissues (2023)

The TB staining method demonstrates significant potential as an effective imaging technique for the identification of fluorescing and non-fluorescing biofilms on tissues and in wounds. This approach could lead to improved precision in surface-based treatments and better patient outcomes.
One influenza virus particle packages eight unique viral RNAs as shown by FISH analysis (2012)

Influenza A virus possesses a segmented genome of eight negative-sense, single-stranded RNAs. The eight segments have been shown to be represented in approximately equal molar ratios in a virus population; however, the exact copy number of each viral RNA segment per individual virus particles has not been determined. We have established an experimental approach based on multicolor single-molecule fluorescent in situ hybridization (FISH) to study the composition of viral RNAs at single-virus particle resolution. Colocalization analysis showed that a high percentage of virus particles package all eight different segments of viral RNAs. To determine the copy number of each RNA segment within individual virus particles, we measured the photobleaching steps of individual virus particles hybridized with fluorescent probes targeting a specific viral RNA. By comparing the photobleaching profiles of probes against the HA RNA segment for the wild-type influenza A/Puerto Rico/8/34 (PR8) and a recombinant PR8 virus carrying two copies of the HA segment, we concluded that only one copy of HA segment is packaged into a wild type virus particle. Our results showed similar photobleaching behaviors for other RNA segments, suggesting that for the majority of the virus particles, only one copy of each RNA segment is packaged into one virus particle. Together, our results support that the packaging of influenza viral genome is a selective process.
MAS1 Receptor Trafficking Involves ERK1/2 Activation Through a β-Arrestin2–Dependent Pathway (2017)

The MAS1 receptor (R) exerts protective effects in the brain, heart, vessels, and kidney. R trafficking plays a critical function in signal termination and propagation and in R resensitization. We examined MAS1R internalization and trafficking on agonist stimulation and the role of β-arrestin2 in the activation of ERK1/2 (extracellular signal-regulated kinase 1/2) and Akt after MAS1R stimulation. Human embryonic kidney 293T cells were transfected with the coding sequence for MAS1R-YFP (MAS1R fused to yellow fluorescent protein). MAS1R internalization was evaluated by measuring the MAS1R present in the plasma membrane after agonist stimulation using a ligand-binding assay. MAS1R trafficking was evaluated by its colocalization with trafficking markers. MAS1R internalization was blocked in the presence of shRNAcaveolin-1 and with dominant negatives for Eps15 (a protein involved in endocytosed Rs by clathrin-coated pits) and for dynamin. After stimulation, MAS1R colocalized with Rab11-a slow recycling vesicle marker-and not with Rab4-a fast recycling vesicle marker-or LysoTracker-a lysosome marker. Cells transfected with MAS1R showed an increase in Akt and ERK1/2 activation on angiotensin-(1-7) stimulation, which was blocked when the clathrin-coated pits pathway was blocked. Suppression of β-arrestin2 by shRNA reduced the angiotensin-(1-7)-induced ERK1/2 activation, whereas Akt activation was not modified. We conclude that on agonist stimulation, MAS1R is internalized through clathrin-coated pits and caveolae in a dynamin-dependent manner and is then slowly recycled back to the plasma membrane. MAS1R induced Akt and ERK1/2 activation from early endosomes, and the activation of ERK1/2 was mediated by β-arrestin2. Thus, MAS1R activity and density may be tightly controlled by the cell.
A new method of measuring static field distribution using modified Fourier NMR imaging (1985)

A new method for mapping the static magnetic field of NMR imagers is presented. The method uses a conventional Fourier imaging pulse-sequence with the exception that the time interval between the 90 degrees and 180 degrees pulses does not equal that between the 180 degrees pulse and spin-echo formation. In images obtained from the pulse sequence, the difference between those two time intervals causes phase shifts that depend on the static magnetic field distribution. Thus, the information on the field distribution can be extracted from these phase shifts. This method is quicker and more easily implemented than the method proposed by Maudsley et al. (1979, 1983, 1984).
An EOG-based wheelchair robotic arm system for assisting patients with severe spinal cord injuries (2019)

The EOG-based HMI can provide sufficient precision control to integrate a wheelchair and a robotic arm into a system which can help patients with SCIs to accomplish a self-drinking task. (ChiCTR1800019764).
Utility of Transesophageal Echocardiogram Surveillance after Watchman Device Placement (2022)

Background: In atrial fibrillation patients undergoing left atrial appendage occlusion with a Watchman device, surveillance imaging with a transesophageal echocardiogram (TEE) is typically performed at 45 days and 1 year to evaluate for device-related thrombus (DRT) and peri-device leak (PDL) before cessation of oral anticoagulation. The incidence of these complications is relatively low, and the ideal timing and duration of surveillance is unknown. We sought to evaluate the incidence of DRT and PDL after Watchman placement at 45 days and 1 year to determine the necessity of surveillance TEEs. Methods: We retrospectively analyzed 361 patients who received a Watchman device between January 2016 and January 2020. Baseline clinical and echocardiographic data, post-procedure antithrombotic therapy and surveillance echocardiographic data were collected from the NCDR LAAO Registry. Nested backward variable elimination regression was performed to derive independent predictors of the composite outcome of DRT and PDL. Results: A total of 286 patients who had post-procedure TEEs were included in the analysis. At 45 days, 9 patients had DRT (3.2%) and 44 patients had PDL (15.0%). At 1 year, 5 patients had DRT (5.6%) and 8 patients had PDL (8.9%). All DRT at 45 days was treated with continued anticoagulation while no change in protocol occurred with PDL. All DRT at 1 year occurred in new patients without prior thrombus. A history of prior transient ischemic attack (TIA) and thromboembolism were significantly associated with DRT or PDL at 1 year. Conclusions: We identified several patients with device-related complications at 45 days and 1 year despite appropriate device sizing and adequate use of antithrombotic therapy. The incidence of DRT increased from 45 days to 1 year and occurred in patients without prior thrombus. These findings highlight the importance of surveillance imaging and suggest the potential need for extended surveillance in select patients.
Effect of Mn doping on the magnetic properties of the post‐annealed Fe48Pt52‐C composite films (2011)

Abstract (Fe 48 Pt 52 ) 1– x Mn x ‐C composite films with different x were fabricated using magnetron sputtering and post‐annealing at 550 °C. Proper Mn doping can improve the ordering of the face‐centered tetragonal (fct) FePt grains. The lattice constant ratio ( c / a ) first decreases, then increases with the increasing x . At x = 2.1%, the minimum c / a of 0.964 and the maximum ordering degree of 0.96 were obtained. All of the films are hard ferromagnetic. The maximum room‐temperature coercivity of the films is 7.5 kOe at x = 2.1% and 10‐kOe field, and the coercivity decreases from 13.3 kOe at 20 K to 10.1 kOe at 300 K under a 90‐kOe field. The reversal mechanism of the films is the coexistence of the domain wall motion and Stoner–Wolhfarth (S‐W) rotation modes.
Principles of Chemical and Biological Sensors. Vol. 150. Chemical Analysis:  A Series of Monographs on Analytical Chemistry and Its Applications By Dermot Diamond (Dublin City University, Dublin, Ireland). John Wiley & Sons, Inc.:  New York. 1998. xxvii + 334 pp. $89.00. ISBN 0-471-54619-4. (1999)

ADVERTISEMENT RETURN TO ISSUEPREVBook ReviewPrinciples of Chemical and Biological Sensors. Vol. 150. Chemical Analysis: A Series of Monographs on Analytical Chemistry and Its Applications By Dermot Diamond (Dublin City University, Dublin, Ireland). John Wiley & Sons, Inc.: New York. 1998. xxvii + 334 pp. $89.00. ISBN 0-471-54619-4.Zeev RosenzweigView Author Information University of New OrleansCite this: J. Am. Chem. Soc. 1999, 121, 27, 6522Publication Date (Web):June 5, 1999Publication History Published online5 June 1999Published inissue 1 July 1999https://doi.org/10.1021/ja985737rCopyright © 1999 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views137Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (13 KB) Get e-AlertsSUBJECTS:Bioengineering and biotechnology,Biotechnology,Chemical engineering and industrial chemistry,Sensors Get e-Alerts
KÁNARA (NORTH KÁNARA) (2012)

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Generative Adversarial Network for Radar Signal Synthesis (2019)

A major obstacle in ultra-wideband radar based approaches for object detection concealed on human body is the difficulty in collecting high quality radar signal data. Generative adversarial networks (GAN) have shown promise in synthesizing data for image and audio processing. This paper proposes the design of a GAN for application in radar signal generation. Data collected using the Finite-Difference Time-Domain (FDTD) method on three concealed object classes (no object, large object, and small object) are used as training data. A GAN is trained to generate radar signal samples for each class. The proposed GAN is capable of synthesizing the radar signal data which is indistinguishable from the training data by qualitative analysis performed by human observers.
Axiparabola: a long-focal-depth, high-resolution mirror for broadband high-intensity lasers (2019)

Diffraction puts a fundamental limit on the distance over which a light beam can remain focused. For about 30 years, several techniques to overcome this limit have been demonstrated. Here, we propose a reflective optics, namely, the axiparabola, that allows to extend the production of "diffraction-free" beams to high-peak-power and broadband laser pulses. We first describe the properties of this aspheric optics. We then analyze and compare its performances in numerical simulations and in experiments. Finally, we use it to produce a plasma waveguide that can guide an intense laser pulse over 10 millimeters.
Platelet-mediated proteolytic down regulation of the anticoagulant activity of protein S in individuals with haematological malignancies (2012)

The natural anticoagulant protein S contains a so-called thrombin- sensitive region (TSR), which is susceptible to proteolytic cleavage. We have previously shown that a platelet-associated protease is able to cleave protein S under physiological plasma conditions in vitro . The aim of the present study was to investigate the relation between platelet-associated protein S cleaving activity and in vivo protein S cleavage, and to evaluate the impact of in vivo protein S cleavage on its anticoagulant activity. Protein S cleavage in healthy subjects and in thrombocytopenic and thrombocythaemic patients was evaluated by immunological techniques. Concentration of cleaved and intact protein S was correlated to levels of activated protein C (APC)-dependent and APC-independent protein S anticoagulant activity. In plasma from healthy volunteers 25% of protein S is cleaved in the TSR. While in plasma there was a clear positive correlation between levels of intact protein S and both APC-dependent and APC-independent protein S anticoagulant activities, these correlations were absent for cleaved protein S. Protein S cleavage was significantly increased in patients with essential thrombocythaemia (ET) and significantly reduced in patients with chemotherapy-induced thrombocytopenia. In ET patients on cytoreductive therapy, both platelet count and protein S cleavage returned to normal values. Accordingly, platelet transfusion restored cleavage of protein S to normal values in patients with chemotherapy-induced thrombocytopenia. In conclusion, proteases from platelets seem to contribute to the presence of cleaved protein S in the circulation and may enhance the coagulation response in vivo by down regulating the anticoagulant activity of protein S.