gebhart/patrepeval huggingface dataset:
Dissipative production of a maximally entangled steady state (2013)

Entangled states are a key resource in fundamental quantum physics, quantum cryp-tography, and quantum computation [1].To date, controlled unitary interactions applied to a quantum system, so-called "quantum gates", have been the most widely used method to deterministically create entanglement [2]. These processes require high-fidelity state preparation as well as minimizing the decoherence that inevitably arises from coupling between the system and the environment and imperfect control of the system parameters. Here, on the contrary, we combine unitary processes with engineered dissipation to deterministically produce and stabilize an approximate Bell state of two trapped-ion qubits independent of their initial state. While previous works along this line involved the application of sequences of multiple time-dependent gates [3] or generated entanglement of atomic ensembles dissipatively but relied on a measurement record for steady-state entanglement [4], we implement the process in a continuous time-independent fashion, analogous to optical pumping of atomic states. By continuously driving the system towards steady-state, the entanglement is stabilized even in the presence of experimental noise and decoherence. Our demonstration of an entangled steady state of two qubits represents a step towards dissipative state engineering, dissipative quantum computation, and dissipative phase transitions [5-7]. Following this approach, engineered coupling to the environment may be applied to a broad range of experimental systems to achieve desired quantum dynamics or steady states. Indeed, concurrently with this work, an entangled steady state of two superconducting qubits was demonstrated using dissipation [8].
Korea-U.S. FTA and the Gaesong Industrial Complex: Conflict and Issues (2007)

미국과의 자유무역협정(FTA) 협상 과정에서 논의된 개성공단 생산제품의 한국산 원산지 인정문제는 본질상 남북관계와 대북정책에 대한 한미간 입장 차이의 조정문제이다. 개성공단 문제는 원산지 관련 관세문제이며, 핵심은 북한이 테러지원국에서 해제되고 적성국교역법의 대상에서 벗어나는 정치적 문제이다. 북미 관계가 정상화되고 북한이 국제사회의 일원으로서 WTO 가입국가가 되면 개성공단 제품은 정상관세로 수출될 수 있을 것이다. 따라서 경제적 주고받기를 계산하는 자유무역협정 협상과정에서 이 문제를 지나치게 고집할 경우 미국의 양보를 얻기 위해 우리가 보다 큰 경제적 손실을 감수해야 할 가능성이 농후하다. 이러한 상황에서 한-미 FTA에서 개성공단 제품의 한국산 인정에 과연 가장 높은 정책적 우선순위를 두는 것이 타당한 지 재고해 볼 필요가 있다. 무리한 접근은 결국 국익에 부담이 된다는 점에서 더욱 그러하다. 개성공단 문제는 한미간 신뢰의 증진과 더불어 대북정책 조정을 위한 별도의 채널을 통해 지속적으로 논의할 필요가 있다.
Energy Storage in Electrochemical Cells with Molten Sb Electrodes (2012)

An energy-storage concept is proposed using molten Sb as the fuel in a reversible solid-oxide electrochemical cell (SOEC). Because both Sb and Sb2O3 are liquids at typical SOEC operating temperatures, it is possible to flow Sb from an external tank and use it as the fuel under fuel-cell conditions and then electrolyze Sb2O3 during recharging. This concept was tested using a button cell with a Sc-stabilized zirconia electrolyte at 973 K by measuring the impedances under fuel-cell and electrolyzer conditions for a range of stirred Sb-Sb2O3 compositions. The Sb-Sb2O3 electrode impedances were found to be on the order of 0.15 Ωcm2 for both fuel-cell and electrolyzer conditions, for compositions up to 30% Sb and 70% Sb2O3. The open circuit voltages (OCV) were 0.75 V, independent of oxygen composition. Some features of using molten Sb as an energy-storage medium are discussed.
Intracellular cholesterol biosynthesis in enchondroma and chondrosarcoma (2019)

Enchondroma and chondrosarcoma are the most common benign and malignant cartilaginous neoplasms. Mutations in isocitrate dehydrogenase 1 and 2 (IDH1/2) are present in the majority of these tumors. We performed RNA-seq analysis on chondrocytes from Col2a1Cre;Idh1LSL/+ animals and found that genes implied in cholesterol synthesis pathway were significantly upregulated in the mutant chondrocytes. We examined the phenotypic effect of inhibiting intracellular cholesterol biosynthesis on enchondroma formation by conditionally deleting SCAP (sterol regulatory element-binding protein cleavage-activating protein), a protein activating intracellular cholesterol synthesis, in IDH1 mutant mice. We found fewer enchondromas in animals lacking SCAP. Furthermore, in chondrosarcomas, pharmacological inhibition of intracellular cholesterol synthesis significantly reduced chondrosarcoma cell viability in vitro and suppressed tumor growth in vivo. Taken together, these data suggest that intracellular cholesterol synthesis is a potential therapeutic target for enchondromas and chondrosarcomas.
Fluorescence Resonance Energy Transfer-Based HIV-1 Virion Fusion Assay (2004)

The fluorescence resonance energy transfer (FRET)-based HIV-1 virion fusion assay exploits the incorporation of beta-lactamase-Vpr chimeric proteins into HIV-1 virions and their subsequent delivery into the cytoplasm of target cells as a marker of fusion. This transfer can be monitored by the enzymatic cleavage of the CCF2-AM dye, a fluorescent substrate of beta-lactamase (BlaM), loaded into the target cells. BlaM cleavage of the beta-lactam ring in CCF2-AM prevents the FRET between the coumarin and fluorescein moieties of the dye. This cleavage changes the fluorescence emission spectrum of CCF2-AM from green (520 nm) to blue (447 nm), and thus permits detection of fusion by fluorescence microscopy, flow cytometry, or UV photometry. This assay is simple and rapid to perform, and exhibits high sensitivity and specificity. Importantly, it can be applied to study HIV-1 virion fusion in primary cells and can be combined with immunostaining for subset discrimination in heterogeneous target cell populations. Finally, the assay can also be adapted to study fusion mediated by the envelope proteins from other viruses through the construction of HIV-1 pseudotypes.
[Acne-pustulosis-hyperostosis-osteitis syndrome. Results of a national survey. 85 cases]. (1987)

The authors report the data collected by a national investigation organized by the French Society of Rheumatology, concerning the osteo-articular manifestations of severe acne, palmo-plantar pustulosis and primary thoracic and peripheral hyperostosis. This investigation collected 85 case-reports including 13 severe acne, 44 PPP and 28 hyperostosis without the dermatitis mentioned above. From this investigation, it appears that dermatological and osseous pictures described under various denominations, present common characteristics and transition forms justifying their common study under the acronym SAPHO (Syndrome Acne-Pustulosis-Hyperostosis-Osteitis). The bony involvement, especially anterior thoracic, but also vertebral and even peripheral seems to be the common denominator between these diseases. It realizes a true rheumatoid inflammatory osteitis, osseous counterpart of synovial and cartilagenous affections in inflammatory rheumatoid diseases. This group has rather loose connections with common psoriasis and slightly more definite relationships with primary ankylosing spondylarthritis. These clinical and immunogenetic connections occur also through bony involvement.
Rabbit Monoclonal Antibody Specifically Recognizing a Linear Epitope in the RBD of SARS-CoV-2 Spike Protein (2021)

To date, SARS-CoV-2 pandemic has caused more than 188 million infections and 4.06 million deaths worldwide. The receptor-binding domain (RBD) of the SARS-CoV-2 spike protein has been regarded as an important target for vaccine and therapeutics development because it plays a key role in binding the human cell receptor ACE2 that is required for viral entry. However, it is not easy to detect RBD in Western blot using polyclonal antibody, suggesting that RBD may form a complicated conformation under native condition and bear rare linear epitope. So far, no linear epitope on RBD is reported. Thus, a monoclonal antibody (mAb) that recognizes linear epitope on RBD will become valuable. In the present study, an RBD-specific rabbit antibody named 9E1 was isolated from peripheral blood mononuclear cells (PBMC) of immunized rabbit by RBD-specific single B cell sorting and mapped to a highly conserved linear epitope within twelve amino acids <sup>480</sup>CNGVEGFNCYFP<sup>491</sup> on RBD. 9E1 works well in Western blot on S protein and immunohistochemistry on the SARS-CoV-2 infected tissue sections. The results demonstrated that 9E1 can be used as a useful tool for pathological and functional studies of SARS-CoV-2.
Histopathologic and Radiologic Assessment of Chemotherapeutic Response in Ewing's Sarcoma: A Review (2012)

Ewing's sarcoma is a highly malignant tumor that metastasizes rapidly and is thus associated with a low survival rate. The intensification of chemotherapy has been shown to improve the overall survival of patients with Ewing's sarcoma. However, intensified chemotherapy can lead to increased toxicity or even the development of secondary malignancies. The stratification of patients with Ewing's sarcoma into "good" and "poor" responders may help guide the administration of progressively more intensified chemotherapy. Thus, an accurate assessment of the chemotherapeutic response, as well as the extent of chemotherapy-induced tumor necrosis, is critical for avoiding potential treatment-related complications in these patients. This paper reviews the methods currently used to evaluate chemotherapeutic response in Ewing's sarcoma, focusing specifically on histopathologic and imaging analyses, and discusses novel therapies and imaging methods that may help improve the overall survival of these patients.
Improved Gender Classification Using Nonpathological Gait Kinematics in Full-Motion Video (2015)

In this paper, we exploit nonpathological gait kinematics to improve gender classification from motion information using large-scale datasets with subjects moving in a less controlled environment. Dynamic motion features are extracted from motion capture data using principal component analysis. Features are further refined in the time and spatial domain by exploiting gait phase cycles and significant body part indicators obtained from analyzing nonpathological gait kinematics. Classification is performed using support vector machine with a radial basis function. Experimental testing with a dataset of 49 subjects reveals that human gender classification rates are improved from 73% to 93% using leave-one-out cross validation.
COAL AND BIOMASS GASIFICATION FOR SNG PRODUCTION (2016)

Within the production of synthetic natural gas - basically methane-from solid feed stock such as coal or biomass the major conversion step is gasification, generating a product gas containing a mixture of permanent and condensable gases, as well as solid residues. The gasification step can be conducted in different atmospheres and using different reaction agents. This chapter discusses the role of gasification for the overall substitute natural gas (SNG) process, and the basic thermodynamic aspects within gasification. The gasification process is a series of different conversions involving both homogeneous and heterogeneous reactions. The basic steps from solid fuel to product gas are drying, pyrolysis, and gasification. From a technological viewpoint, there basically exist three different gasification reactor types that are used at large scale: fixed bed reactors, entrained flow reactors, and fluidized bed reactors. Coal is mainly used in entrained flow gasification or fixed bed units, whereas biomass gasification is mostly done in fluidized bed reactors. © 2016 by John Wiley &amp; Sons, Inc. All rights reserved.
Characteristics of Impactful Computational Contributions to The Journal of Physical Chemistry C (2020)

ADVERTISEMENT RETURN TO ISSUEEditorialNEXTCharacteristics of Impactful Computational Contributions to The Journal of Physical Chemistry CA. N. AlexandrovaA. N. AlexandrovaUniversity of California, Los AngelesMore by A. N. Alexandrovahttp://orcid.org/0000-0002-3003-1911, Z.-P. LiuZ.-P. LiuFudan UniversityMore by Z.-P. Liuhttp://orcid.org/0000-0002-2906-5217, J. R. SchmidtJ. R. SchmidtUniversity of Wisconsin-MadisonMore by J. R. Schmidthttp://orcid.org/0000-0002-1438-117X, W. F. Schneider*W. F. SchneiderUniversity of Notre DameMore by W. F. Schneiderhttp://orcid.org/0000-0003-0664-2138, and G. C. SolomonG. C. SolomonUniversity of CopenhagenMore by G. C. Solomonhttp://orcid.org/0000-0002-2018-1529Cite this: J. Phys. Chem. C 2020, 124, 25, 13509–13510Publication Date (Web):June 25, 2020Publication History Published online25 June 2020Published inissue 25 June 2020https://pubs.acs.org/doi/10.1021/acs.jpcc.0c04150https://doi.org/10.1021/acs.jpcc.0c04150editorialACS PublicationsCopyright © 2020 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views6032Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (530 KB) Get e-AlertscloseSUBJECTS:Computational modeling,Electronic structure,Materials,Physical chemistry,Theoretical models Get e-Alerts
Clinical characteristics of loss-of function mutations in TBK1 in Belgian FTD and ALS patients (2015)

Frontiers Events is a rapidly growing calendar management system dedicated to the scheduling of academic events. This includes announcements and invitations, participant listings and search functionality, abstract handling and publication, related events and post-event exchanges. Whether an organizer or participant, make your event a Frontiers Event!
Potassium Bromide as Space Holder for Titanium Foam Preparation (2013)

Titanium (Ti) alloy foam was prepared by using potassium bromide (KBr) as space holder with percentage between 20 to 40 wt.%. In this work, the potential of KBr as a new space holder was determined. The Ti alloy powder and space holder were first manually mixed before being compacted using hydraulic hand press. The green compacts were then sintered at temperature of 1160°C, 1200°C and 1240°C in a tube furnace. The microstructure of the Ti alloy foams were observed by Scanning Electron Microscope (SEM). It was revealed that the porosity content in the Ti foam was in the range of 16% to 31% and density in the range of 1.5 g/cm 3 to 2.6 g/cm 3 . Moreover, the pore size of the titanium alloy foam is in the range of 187μm to 303μm. Although the sintering temperatures were found incapable of promoting overall densification to the Ti alloy foam, 1200°C was denoted to be the maximal temperature for promoting maximal porosity to the Ti alloy foam. Nonetheless, KBr was proven to be suitable as space holder for Ti foam preparation as referred to its stability and insolubility in the Ti alloy.
1,2-Substituted 4-(1H)-Quinolones: Synthesis, Antimalarial and Antitrypanosomal Activities in Vitro (2014)

A diverse array of 4-(1H)-quinolone derivatives bearing substituents at positions 1 and 2 were synthesized and evaluated for antiprotozoal activities against Plasmodium falciparum and Trypanosoma brucei rhodesiense, and cytotoxicity against L-6 cells in vitro. Furthermore, selectivity indices were also determined for both parasites. All compounds tested showed antimalarial activity at low micromolar concentrations, with varied degrees of selectivity against L-6 cells. Compound 5a was found to be the most active against P. falciparum, with an IC50 value of 90 nM and good selectivity for the malarial parasite compared to the L-6 cells. Compound 10a, on the other hand, showed a strong antitrypanosomal effect with an IC50 value of 1.25 µM. In this study side chain diversity was explored by varying the side chain length and substitution pattern on the aliphatic group at position-2 and a structure-antiprotozoal activity study revealed that the aromatic ring introduced at C-2 contributed significantly to the antiprotozoal activities.
Reconfigurable behavior of CdTe quantum dots at terahertz frequencies employing UV excitation (2017)

We report the synthesis and characterization of cadmium-telluride (CdTe) quantum dots (QDs) and their performance at Terahertz frequencies employing THz time-domain spectroscopy (THZ-TDS). The data was analyzed using a combination of Fast Fourier Transform (FFT) and effective medium theory to obtain the optical characteristics of the aforementioned CdTe QDs. Additionally, we performed similar measurements while exposing the QDs to a UV excitation with a wavelength of 302 nm and observed a noticeable variation in both the real and imaginary components in the index of refraction that could prove crucial in the demonstration of reconfigurable devices operating in the THz regime.
Long-Term Effects of Radiofrequency, Infrared, and Gas-Plasma Treatments on Alfalfa Seed (1983)

ABSTRACT SAMPLES from three commercial alfalfa, Medicago sativa L., seed lots were subjected to a series of exposures to radiofrequency, infrared, and gas-plasma electrical treatments in 1962 and tested for germination during the subsequent 19-yr period. Radiofrequency and infrared treatments were applied to 27 alfalfa seed lots in 1965, and samples from these experiments were tested three times during the 16-yr period following treatment. Substantial reductions in hard-seed percentages and corresponding increases in normal seedling germination were achieved in all seed lots as determined by tests immediately after treatment. Effectiveness of the three kinds of treatment was about the same. Hard-seed contents of untreated samples diminished gradually for natural reasons in storage at 4 C and 50% relative humidity, but at the end of the long-term storage periods, treated samples of some lots still had significantly lower percentages of hard seed and higher normal germination counts than did untreated samples of the same seed lots. Because these treatmentswhen given at proper exposuresproduced no detrimental effects, even in long-term storage, they offer an alternative to mechanical scarification for reducing hard-seed contents in alfalfa seed
Renal Damage Susceptibility and Autoregulation in <i>Rf-1</i> and <i>Rf-5</i> Congenic Rats (2005)

The Rf-5 QTL does not show any direct effect. The Rf-1 QTL carries one or more genes impairing renal autoregulation and influencing renal damage susceptibility. Whether these are the same genes remains to be established.
Non-clinical development of ozanezumab: a humanised antibody targeting the amino terminus of neurite outgrowth inhibitor A (Nogo-A) (2015)

Ozanezumab (GSK1223249) is a humanised, Fc-disabled, monoclonal antibody (mAb) which targets the amino terminus of Neurite Outgrowth Inhibitor A (Nogo-A) which is currently being developed for the treatment of amyotrophic lateral sclerosis (ALS).
Differential effects of STAT proteins on growth hormone-mediated IGF-I gene expression (2014)

Growth hormone (GH) plays a key role regulating somatic growth and in controlling metabolism and other physiological processes in humans and other animal species. GH acts by binding to the extracellular part of its transmembrane receptor, leading to induction of multiple intracellular signal transduction pathways that culminate in changes in gene and protein expression. A key agent in GH-stimulated growth is the latent transcription factor signal transducer and activator of transcription (STAT) 5B, one of four STAT proteins induced by the GH receptor in cultured cells and in vivo. As shown by genetic and biochemical studies, GH-activated STAT5B promotes transcription of the gene encoding the critical growth peptide, insulin-like growth factor-I (IGF-I), and natural null mutations of STAT5B in humans lead to growth failure accompanied by diminished IGF-I expression. Here we have examined the possibility that other GH-activated STATs can enhance IGF-I gene transcription, and thus potentially contribute to GH-regulated somatic growth. We find that human STAT5A is nearly identical to STAT5B in its biochemical and functional responses to GH but that STAT1 and STAT3 show a weaker profile of in vitro binding to STAT DNA elements from the IGF-I gene than STAT5B, and are less potent inducers of gene transcription through these elements. Taken together, our results offer a molecular explanation for why STAT5B is a key in vivo mediator of GH-activated IGF-I gene transcription and thus of GH-regulated somatic growth.
Limited fine hand use after stroke and its association with other disabilities (2008)

Limited fine hand use is common after acute stroke. Our results suggest that, with time after stroke, upper extremity movements and self-care become less dependent on fine hand use and fine hand use becomes less dependent on touch function, although no ultimate conclusions can be drawn on causality.
A CMOS IC for portable EEG acquisition systems (1998)

We present a monolithic low-power, low-noise analog front-end electroencephalogram acquisition system. It draws only 500 /spl mu/A from a standard 9-V battery, making it suitable for use in portable systems. Although fabricated in a standard CMOS technology, by using current feedback techniques it achieves a common mode rejection ratio of 100 dB while the total input noise referred to input is kept below 1.5 /spl mu/V (rms).
The Potentiometric Studies on the Effects of Various Functional Groups in Disiloxane as an Anion-Selective Ionophore (2005)

The potentiometric responses for various anions are investigated with membrane electrode (membrane 1) based on 1,3-diethyl-1,3-dihydroxy-1,3-bis(2-dimethylaminomethyl ferrocenyl) disiloxane. The nitrate ion-selective electrode based on compound 1 gave a good Nernstian response of 58.18 mV per decade for nitrate with the detection limit of −e5.66 of log [NO3−e]. Compound 1 has all those functional groups and the other two compounds have less functional group of ferrocenyl or ferrocenyl and hydroxide, respectively. Even though, potentiometric response to anions was excellent at pH 5, the selectivity pattern for all three membrane electrode based on series of disiloxane is almost like Hofmeister sequence at pH 5. However, the membrane electrode 1-3 exhibited very different response to anions at pH 7. In this pH, NH2 is not protonated and ionophore may act as neutral carrier. Hydrogen bond may enhance the responsibility to hydrogen acceptors and intramolecular electro-active site may increase the permeability of analyte to ionophore in membrane.