gebhart/patrepeval huggingface dataset:
Some results on biorthogonal-like functions for generalized Gabor expansions (2002)

Summary form only given. The decomposition and representation of signals in the joint time-frequency domain are increasingly useful in communication and information theory, and in signal processing. Given a countable collection of functions in the joint time-frequency domain, we may find another countable collection of joint time-frequency functions, such that any signal can be represented in terms of the two collections of functions. The associated technique is usually called the discrete Gabor transform or short-time Fourier transform, and is valid for both continuous-time and discrete-time signals. One of the collections of functions is defined by a synthesis function, and the other collection is defined by an analysis function. We show that: (1) the collection of biorthogonal-like functions are complete and, hence, the generalized Gabor expansion is well-defined; (2) the technique for addressing the existence of the collection of biorthogonal-like functions is simple, hence, more applicable in practice; and (3) the computation of analysis and synthesis functions is simple and very efficient for both continuous-time and discrete-time signals.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Synthesis of tris(aminomethyl)phosphine oxide and its carbon dioxide adduct from tetrakis(hydroxymethyl)phosphonium salts via their methyl carbamate derivatives (1981)

Tris(aminomethyl)phosphine oxide (6) can be synthesized from octakis(hydroxymethyl)diphosphonium sulfate (1b) in an overall yield of 54.6% via the methyl carbamate derivatives 2b, 3, and 4. On a preparative scale, the last step is complicated by the formation of a cyclic by-product 8 in amounts up to 20% of the total. The triamine 6 forms a 1:1 adduct (11) with carbon dioxide, whose structure, established by 1 H and 13 C nmr, consists of equimolar amounts of carbamate A and dicarbamate BC. The components A, B, and C can be separated by ion exchange. Thermolysis of 11 regenerates 6 smoothly, providing a convenient method for purifying the triamine.
Spontaneous Chiral Segregation in Bidimensional Films (1995)

We have monitored spontaneous chiral segregation in Langmuir films of a racemic mixture of $D$ and $L$ myristoyl-alanine. Following monolayer deposition, we observe first a strong chiral discrimination, followed at longer times by a spatial segregation between $D$ and $L$ domains. Evidence for discrimination has been obtained by surface pressure/area per molecule measurements, whereas segregation is inferred from optical observations using epifluorescence microscopy and from an analysis of the lattice symmetry using x-ray diffraction.
GNSS Antenna Arrays and RTK: The Effect of Carrier Phase Distortions Induced by Spatial Filtering on RTK Positioning (2022)

New GNSS applications demand resilience against radio interference and high position accuracy. Separately, these demands can be fulfilled by multi-antenna systems using spatial filtering and carrier phase positioning algorithms like Real Time Kinematics (RTK), respectively. However, combining these approaches encounters a severe issue: The spatial filtering induces a phase offset into the measured carrier phase leading to a loss of position accuracy. This paper presents a new approach to compensate the phase offset in a blind manner, i.e., without knowing the antenna array radiation pattern or the direction of arrival of the signals. The proposed approach is experimentally validated in two jamming scenarios. One includes a jammer with increasing power and the other includes a moving jammer. The results demonstrate that the approach successfully compensates for the phase offset and, hence, allows the combined use of RTK positioning and spatial filtering even under jamming.
Implementation of a Gigabit Per Second Millimetre Wave Transceiver on CMOS (2007)

Modern systems require transceivers that deliver gigabit speeds, are smaller in size, and have lower power consumption and cost. This motivates research to develop transceiver-on-chip and transceiver-in-a-package technologies. Recent advances in millimetre wave electronics have meant that significant portions of the system can now be integrated onto a single substrate or package. In order to achieve low costs and high digital integration CMOS is the process of choice as CMOS is the standard and a cost effective process for building digital circuits. Unfortunately compared to other much more expensive processes such as SiGe and GaAs, CMOS has greater process variability, lower carrier mobility constants, and smaller device breakdown voltages. This makes millimetre wave wireless transceiver on a chip design particularly challenging. In this paper we outline the development of a gigabit transceiver-on-chip using CMOS and outline the performance of the fabricated components.
Content-adaptive Temporal Search Range Control Based on Frame Buffer Utilization (2006)

Multiple reference frame selection adopted by the state-of-art H.264 video compression standard offers substantial performance gain. The temporal search range control, as a consequence, is crucial for maintaining the coding performance with minimum complexity. In this paper, we investigate the relationships between the reference frame buffer utilization and the optimal search range. A content-adaptive algorithm is proposed to control the search range dynamically during the encoding process. Experimental results show that our algorithm can rapidly adapt to the video characteristics and effectively reduce the complexity with negligible coding performance penalty.
The agronomic performance of ratoon and modified ratoon salibu in the multi-canopy rice cultivation system (2023)

Abstract The use of multi-canopy technology by intercropping and modified ratoon techniques called “salibu” in rice cultivation is expected to have the benefit the increasing yield potency through a vertical harvesting area and cropping index. The purpose of this study was to investigate rice growth and production by the modified ratoon salibu on a multi-canopy cropping system. The multi-canopy was performed by planting a short variety (Inpari 33 and Inpari 43) intercrop with a tall variety (IPB 9G). The short varieties were transplanted with growing space 4:1 with a distance of 30 to 15 cm, and the tall type was transplanted in between rows. After the main-crops were harvested, conventional and modified ratoon salibu were conducted and observed on growth and production. The performance of multi-canopy showed a higher yield compared to that of monoculture. The modified ratoon salibu technique was better than the conventional ratoon in most of the morphological and physiological traits, as well as for grain yield. Utilizing taller rice as intercropping for multi-canopy combined with modified ratoon salibu could be recommended for gaining the benefit of the cropping index as a land utilization strategy.
Body Mass Index as a Predictor of Complications After Operative Treatment of Acetabular Fractures (2005)

Body mass index is predictive of complications after operative treatment of acetabular fractures.
Cytoplasmic localization of a mutant M(r) 160,000 topoisomerase II alpha is associated with the loss of putative bipartite nuclear localization signals in a drug-resistant human lung cancer cell line. (1995)

Many clinically important antineoplastic agents exert their cytotoxicity through interaction with the M(r) 170,000 topoisomerase II alpha, an essential nuclear enzyme. Resistance to these agents has been associated frequently with either a decrease in the levels of topoisomerase II alpha or a qualitative change that alters the interaction of this enzyme with a drug or DNA. Using a VP-16-selected lung cancer cell line, H209/V6, we have identified a third resistance mechanism which involves an aberrant subcellular location of the topoisomerase II alpha isoenzyme. We have shown previously that H209/V6 cells express two topoisomerase II alpha mRNAs (6.1 and 4.8 kilobases) but only a single catalytically active protein which has a M(r) of 160,000 and is located primarily in the cytoplasm (Mirski et al., Cancer Res., 53: 4866-4873, 1993; Feldhoff et al., Cancer Res., 54: 756-762, 1994). In the present study we have determined that this mutant M(r) 160,000 topoisomerase II alpha is encoded by the shorter 4.8-kilobase mRNA. The sequencing of reverse transcriptase-PCR products from H209/V6 cells and subsequent Northern blot analyses showed that a sequence of 988 nucleotides from the 3'-coding and 3'-noncoding region of the normal topoisomerase II alpha is absent from the 4.8-kilobase mRNA. This shorter mRNA is predicted to encode a topoisomerase II alpha protein that no longer contains the 109 COOH-terminal amino acids of the normal enzyme but instead contains 34 new amino acids encoded by a sequence that was previously in the 3'-noncoding region of the mRNA. Confirmation that the COOH terminus of topoisomerase II alpha is no longer present in the M(r) 160,000 protein in H209/V6 cells was obtained by immunoblot analysis. Sequence analyses indicate that 3 putative bipartite nuclear localization signals in the M(r) 160,000 protein are disrupted or lost. Our results suggest that sequences within the COOH-proximal domain of human topoisomerase II alpha serve an important nuclear localization function.
High Endothelin-1 in the Airways of Preterm Infants Is Associated With Less Severe Respiratory Distress During the Early Postnatal Period (1997)

The association of high ET-1 in the airways with less severe respiratory distress in the early postnatal period may be attributable to effects of ET-1 on surfactant secretion or development of airway epithelium.
Adverse reactions to 1975 bivalent influenza vaccine in children. (1977)

A questionnaire survey was undertaken to investigate incidence and types of reactions to a bivalent, zonally purified, killed influenza vaccine administered to 155 children aged 1 to 18 years in 1975. Local or systemic reactions or both occurred in 42 children (27%). However, these reactions were not considered serious and should not constitute a major drawback to future influenza programs in children under 3 years of age.
Acoustic band structure of periodic elastic composites (1993)

We present the first full band-structure calculations for periodic, elastic composites. For transverse polarization of the vibrations we obtain a ``phononic'' band gap which extends throughout the Brillouin zone. A complete acoustic gap or a low density of states should have important consequences for the suppression of zero-point motion and for the localization of phonons, and may lead to improvements in transducers and in the creation of a vibrationless environment.
P4‐028: Developing Targeted Monoclonal Antibody Therapies to Detect and Reverse Cardiac Amyloidosis (2016)

Transthyretin (TTR, or prealbumin) is an abundant blood serum protein which normally forms soluble, stable tetrameric complexes. Under conditions which are not fully understood, the TTR tetramer structure dissociates into aggregation- and misfolding-prone monomers. These monomers aggregate and accumulate as amyloid fibrils and plaques (amyloidosis) throughout the body-particularly in the heart. TTR-related cardiac amyloidosis (TTR-CA) progresses through dysrhythmia and systolic heart failure, leading eventually to overall heart failure and death (Ruberg, 2012). Monoclonal antibodies (mAbs) which specifically recognize and bind to the disease-associated form of TTR via 'cryptotopes' have been developed. Cryptotopes are antigens which are normally deeply buried within a protein but exposed in its altered conformation. Understanding the mAbs mechanism of fibril inhibition is investigated. Four mAbs obtained from Prothena Biosciences (So. South Francisco) were subject to end-point immunogold and initial aggregation kinetics electron microscopy studies. Cryptotopes within pathological TTR misfolding intermediates and end-point insoluble TTR fibrils are exposed and effective mAb targets. Monoclonal antibodies targeting pathological protein conformations are potentially effective pharmacotherapies for preventing the progression of protein misfolding diseases using the exemplar of TTR amyloidosis. Ruberg, F. L., Berk, J. L. (2012). Transthyretin (TTR) cardiac amyloidosis. Circulation. 126(10): 1286-1300.
An Achilles' Heel in an Amyloidogenic Protein and Its Repair (2010)

Insulin fibrillation provides a model for a broad class of amyloidogenic diseases. Conformational distortion of the native monomer leads to aggregation-coupled misfolding. Whereas beta-cells are protected from proteotoxicity by hexamer assembly, fibrillation limits the storage and use of insulin at elevated temperatures. Here, we have investigated conformational distortions of an engineered insulin monomer in relation to the structure of an insulin fibril. Anomalous (13)C NMR chemical shifts and rapid (15)N-detected (1)H-(2)H amide-proton exchange were observed in one of the three classical alpha-helices (residues A1-A8) of the hormone, suggesting a conformational equilibrium between locally folded and unfolded A-chain segments. Whereas hexamer assembly resolves these anomalies in accordance with its protective role, solid-state (13)C NMR studies suggest that the A-chain segment participates in a fibril-specific beta-sheet. Accordingly, we investigated whether helicogenic substitutions in the A1-A8 segment might delay fibrillation. Simultaneous substitution of three beta-branched residues (Ile(A2) --> Leu, Val(A3) --> Leu, and Thr(A8) --> His) yielded an analog with reduced thermodynamic stability but marked resistance to fibrillation. Whereas amide-proton exchange in the A1-A8 segment remained rapid, (13)Calpha chemical shifts exhibited a more helical pattern. This analog is essentially without activity, however, as Ile(A2) and Val(A3) define conserved receptor contacts. To obtain active analogs, substitutions were restricted to A8. These analogs exhibit high receptor-binding affinity; representative potency in a rodent model of diabetes mellitus was similar to wild-type insulin. Although (13)Calpha chemical shifts remain anomalous, significant protection from fibrillation is retained. Together, our studies define an "Achilles' heel" in a globular protein whose repair may enhance the stability of pharmaceutical formulations and broaden their therapeutic deployment in the developing world.
Kinetic Evidence for an Acylpyridinium Intermediate in Hydrolysis of p-Nitrophenyl Alkanoates Catalyzed by a Polyamide with 4-(Dialkylamino)pyridine Groups (1996)

ADVERTISEMENT RETURN TO ISSUEPREVCommunication to the...Communication to the EditorNEXTKinetic Evidence for an Acylpyridinium Intermediate in Hydrolysis of p-Nitrophenyl Alkanoates Catalyzed by a Polyamide with 4-(Dialkylamino)pyridine GroupsShanghao Liu and Wilmer K. FifeView Author Information Department of Chemistry, Indiana University−Purdue University at Indianapolis, 402 N. Blackford Street, Indianapolis, Indiana 46202 Cite this: Macromolecules 1996, 29, 9, 3334–3336Publication Date (Web):April 22, 1996Publication History Received26 December 1995Revised4 March 1996Published online22 April 1996Published inissue 1 January 1996https://pubs.acs.org/doi/10.1021/ma9518971https://doi.org/10.1021/ma9518971rapid-communicationACS PublicationsCopyright © 1996 American Chemical SocietyRequest reuse permissionsArticle Views58Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Catalysts,Hydrolysis,Kinetic parameters,Organic reactions,Post-translational modification Get e-Alerts
Characterizing the traffic distribution in linear wireless sensor networks (2008)

In a multi-hop wireless sensor network (WSN), the traffic load is not evenly distributed over the nodes. For example, the sensors which are one hop away from the sink relay the whole network traffic. This imbalanced traffic distribution can degrade the network lifetime and functionality. Here, an analysis is proposed to characterize the traffic load distribution over a randomly deployed linear WSN. The effect of the number of nodes and their distribution over the network is taken into account and the results are verified through computer simulation.
A Method for Simultaneous Optimization of Blank Shape and Forming Tool Geometry in Sheet Metal Forming Simulations (2021)

This paper presents a numerical method for simultaneous optimization of blank shape and forming tool geometry in three-dimensional sheet metal forming operations. The proposed iterative procedure enables the manufacturing of sheet metal products with geometry fitting within specific tolerances (surface and edge deviations less than 0.5 or 1.0 mm, respectively) that prescribe the maximum allowable deviation between the simulated and desired geometry. Moreover, the edge geometry of the product is affected by the shape of the blank and by an additional trimming phase after the forming process. The influences of sheet metal thinning, edge geometry, and springback after forming and trimming are considered throughout the blank and tool optimization process. It is demonstrated that the procedure effectively optimizes the tool and blank shape within seven iterations without unexpected convergence oscillations. Finally, the procedure thus developed is experimentally validated on an automobile product with elaborated design and geometry which prone to large springback amounts owning to complex-phase advanced high strength steel material selection.
Rosiglitazone-Mediated Effects on Skeletal Muscle Gene Expression Correlate with Improvements in Insulin Sensitivity in Individuals with HIV-Insulin Resistance (2011)

Rosiglitazone, an agonist of peroxisome proliferator activated receptor (PPARγ), improves insulin sensitivity by increasing insulin-stimulated glucose uptake into muscle tissue. This study was undertaken to assess changes in expression of PPAR-regulated genes in muscle tissue following treatment of HIV-associated insulin resistance with rosiglitazone. Muscle gene expression was assessed in twenty-two seronegative HIV subjects (control), 21 HIV-infected individuals with normal insulin sensitivity (HIV-IS) and 19 HIV-infected individuals with insulin resistance (HIV-IR). A subset of the HIV-IR group (N = 10) were re-evaluated 12 weeks after treatment with 8 mg/d of rosiglitazone. The HIV-IR group's rosiglitazone-mediated improvement in insulin sensitivity was highly correlated with increased expression of PPARγ and carnitine palmitoyl transferase-1 (CPT-1), (r = 0.87, P < .001) and (r = 0.95, P < .001), respectively. The changes in PPARγ expression were also correlated with the changes in CPT1 expression (r = 0.75, P = .009). The results suggest that rosiglitazone; may have a direct effect on muscle tissue to improve insulin sensitivity.
Central anatomy of individual rapidly adapting low‐threshold mechanoreceptors innervating the “hairy” skin of newborn mice: Early maturation of hair follicle afferents (2001)

Adult skin sensory neurons exhibit characteristic projection patterns in the dorsal horn of the spinal gray matter that are tightly correlated with modality. However, little is known about how these patterns come about during the ontogeny of the distinct subclasses of skin sensory neurons. To this end, we have developed an intact ex vivo somatosensory system preparation in neonatal mice, allowing single, physiologically identified cutaneous afferents to be iontophoretically injected with Neurobiotin for subsequent histological analyses. The present report, centered on rapidly adapting mechanoreceptors, represents the first study of the central projections of identified skin sensory neurons in neonatal animals. Cutaneous afferents exhibiting rapidly adapting responses to sustained natural stimuli were encountered as early as recordings were made. Well-stained representatives of coarse (tylotrich and guard) and fine-diameter (down) hair follicle afferents, along with a putative Pacinian corpuscle afferent, were recovered from 2-7-day-old neonates. All were characterized by narrow, uninflected somal action potentials and generally low mechanical thresholds, and many could be activated via deflection of recently erupted hairs. The central collaterals of hair follicle afferents formed recurrent, flame-shaped arbors that were essentially miniaturized replicas of their adult counterparts, with identical laminar terminations. The terminal arbors of down hair afferents, previously undescribed in rodents, were distinct and consistently occupied a more superficial position than tylotrich and guard hair afferents. Nevertheless, the former extended no higher than the middle of the incipient substantia gelatinosa, leaving a clear gap more dorsally. In all major respects, therefore, hair follicle afferents display the same laminar specificity in neonates as they do in adults. The widely held misperception that their collaterals extend exuberant projections into pain-specific regions of the dorsal horn during early postnatal life is shown to have multiple, deep-rooted underpinnings.
Characterization of Stress Transfer from Process Induced Stressor Layer to Substrate in MOSFETs (2013)

The performance of electronic devices can be improved by applying stress to conduction channel to increase the carrier mobility. This can be achieved using contact etch stop layer (CESL). Its intrinsic stress is transmitted into the silicon substrate, inducing a strain in the conduction channel. This phenomenon results in an enhancement of about 8 % to 10 % of the channel electrical conductivity. Several techniques exist to characterize the stress. Currently, to obtain a high spatial resolution, the only possible solution to characterize the stress is to use TEM-based techniques. Dark-field electron holography has the advantage of producing strain maps that combine a nanometre-scale spatial resolution, a high sensitivity and a large field of view. As a consequence, this technique is employed in this paper to observe the deformation of silicon crystalline lattice in the transistor conduction channel.