gebhart/patrepeval huggingface dataset:
Linéarisation des amplificateurs de puissance micro ondes utilisant une technique de prédistorsion numérique adaptative (2004)

Techniques de linéarisation numériques -- Présentation des articles intégrés dans la thèse -- Experimental implementation and validation of an adaptive digital predistortion technique -- A new adaptive predistortion technique using software-defined radio and DSP technologies suitable for base station 3G power amplifiers.
Hybrid adaptive learning control of nonlinear system (2005)

A hybrid adaptive learning control for nonlinear dynamical systems is proposed. Feedforward multilayer neural networks are used to construct a controller. Parameters of the neural networks are adjusted by a dynamic backpropagation algorithm and a genetic algorithm. The genetic algorithm manages to escape local minima and reach the neighborhood of the global minimum on the squared error surface. The dynamic backpropagation algorithm is used to search the global minimum from its neighborhood. Computer simulations show that the tracking control performance of nonlinear dynamical systems can be enhanced by the proposed method.
Diffusion in mesoporous materials and polymers swelling: a transient calorimetric approach (2008)

The diffusion of water and benzene has been followed by DSC using the thermoporosimetry (TPM) approach. The diffusion of water has been observed during the drying of a water impregnated mesoporous silica gel at 40 degrees C under dry air. It was found that the confinement affects the evaporation rate of water. The diffusion of benzene has been observed during the drying and the swelling of a cross linked PDMS sample. The mesh size distributions (MSD) of the elastomer, during swelling and drying, have been calculated at various times using the TPM formalism. Extrapolating the mean mesh size of the polymeric network, it was found that the dry polymer has an average mesh of about 2.5 nm.
Evaluation of a new mechanical atherectomy system (TRAC) in normal canine coronary arteries (1993)

These results demonstrate that it is feasible and relatively safe to introduce and operate the new TRAC mechanical atherectomy system in the normal coronary arteries of a beating dog heart.
CISTICERCOSIS: DANO CEREBRAL IRREVERSIBLE (1988)

EL FECALISMO AL AIRE LIBRE ES UNO DE LOS FACTORES QUE CONTRIBUYEN A LA PROLIFERACION DE LA CISTICERCOSIS, POR LO CUAL -AFIRMO LA DOCTORA ANA FLISSER, DEL IIB DE LA UNAM, DURANTE EL XII CONGRESO INTERNACIONAL DE MEDICINA TROPICAL Y MALARIA- ES NECESARIO QUE LAS INSTITUCIONES DE SALUD VINCULEN ESFUERZOS CON LAS DEPENDENCIAS ENCARGADAS DE PROPORCIONAR SERVICIOS BASICOS A LA POBLACION.
Expert Panel Discussion among Psoriasis and Psychodermatology Specialists: How Best to Manage Depressed Psoriasis Patients with Brodalumab (2019)

Psoriasis patients with comorbid depression represent a common therapeutic challenge for dermatologists. Depressed patients often require the practicing dermatologist to go outside of their comfort zone, and the FDA’s labeling of medications such as brodalumab have further complicated an already difficult-to-treat patient population. A multi-disciplinary work-group consisting of a board-certified psychiatrist, a licensed clinical psychologist, and multiple dermatologists was convened to formulate practical recommendations for the evaluation and treatment of this at-risk population. How to broach the subject of depression and when to refer patients for formal evaluation were discussed. The expert panel also produced a consensus statement regarding the use of brodalumab in patients with both psoriasis and depression.
HER2 YVMA drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy (2009)

Mutations in the HER2 kinase domain have been identified in human clinical lung cancer specimens. Here we demonstrate that inducible expression of the most common HER2 mutant (HER2(YVMA)) in mouse lung epithelium causes invasive adenosquamous carcinomas restricted to proximal and distal bronchioles. Continuous expression of HER2(YVMA) is essential for tumor maintenance, suggesting a key role for HER2 in lung adenosquamous tumorigenesis. Preclinical studies assessing the in vivo effect of erlotinib, trastuzumab, BIBW2992, and/or rapamycin on HER2(YVMA) transgenic mice or H1781 xenografts with documented tumor burden revealed that the combination of BIBW2992 and rapamycin is the most effective treatment paradigm causing significant tumor shrinkage. Immunohistochemical analysis of lung tumors treated with BIBW2992 and rapamycin combination revealed decreased phosphorylation levels for proteins in both upstream and downstream arms of MAPK and Akt/mTOR signaling axes, indicating inhibition of these pathways. Based on these findings, clinical testing of the BIBW2992/rapamycin combination in non-small cell lung cancer patients with tumors expressing HER2 mutations is warranted.
A Verilog preprocessor for representing datapath components (2002)

Describes research leading to the generation of a preprocessor for the Verilog hardware description language. The function of this preprocessor is to support repeated feature instances in a Verilog description for a digital system. Repeated features most commonly occur in the description of datapaths, where iterative structures like adders, multipliers and muxes are the basic building blocks. Citations from Verilog users and industry organizations in support of inclusion of a repeated feature syntax are given. Several syntaxes for describing repeated features are presented. From these proposals, a single syntax for support of repeated feature instances is selected. A preprocessor is described that will parse the extended Verilog and translate it to supported Verilog. The challenges in the generation of the preprocessor are given. The paper concludes with a status report on the preprocessor and thoughts for future development.
Chiral Auxiliaries and Ligands in Asymmetric Synthesis (1995)

Enantiomerically Pure Chiral Auxiliaries. Chiral Reagents. Chiral Catalysis and Catalysts Bearing Chiral Ligands. Asymmetric Deprotonations and Protonations. Alkylations and Related Reactions. Additions to C=O and C=N Double Bonds. Additions to Carbon--Carbon Double Bonds. Additions to Double Bonds Bearing Heteroatoms Oxidations of Sulfides and Selenides. Cycloadditions. Sigmatropic Rearrangements. Transition Metal Catalyzed Reactions. References. Index.
Dynamic modeling of ph electrodes (1978)

Abstract A mathematical model for the dynamic behavior of the pH glass electrode is presented. The model results from a description of ionic transport in an assumed stagnant boundary layer around the electrode surface. Documented information regarding the characteristics and operation of the glass electrode and the mechanism of pH measurements is combined with dynamic mass balances in an attempt to describe its transient response. New experimental results are presented which indicate both the validity of the model and that double layer effects are also contributors to the dynamic response. One of the interesting features of the model is that it predicts that if an electrode is subjected to a step change from a solution of a strong acid at a given pH to another solution of the same acid at the same pH but containing a salt of that acid, a transient response will result. This effect has been observed experimentally and is due to the differences in the diffusivities of the various ionic species present in the solutions.
ChemInform Abstract: MERCURY IN ORGANIC CHEMISTRY. 31. PREPARATION OF ALLENIC AND PROPARGYLIC ORGANOMERCURIC HALIDES (1984)

Abstract Aus den Propargyl: halogeniden (I) entstehen die Chlormercuri‐Derivate (II), aus (III) werden die isomeren Allene (IV)‐ erhalten, aus dem Alkin‐halogenid (V) entsteht gleichfalls ein Allenyl‐Derivat (VI).
Control design of a STATCOM with Energy Storage System for stability and power quality improvements (2009)

This paper presents a robust control scheme for a static synchronous compensator (STATCOM) coupled with a battery energy storage system (BESS) for improving the dynamic oscillations damping and the transmission power quality in electric power systems. The presented STATCOM/BESS controls both reactive and active power injection/absorption to/from the power system. It is investigated the performance of a supplementary damping controller (SDC) added to the reactive power control scheme. The SDC is designed by a robust control technique structured in the form of linear matrix inequalities (LMIs). The main objectives, from the application viewpoint, are the improvements of the damping of oscillations in tie-lines (precisely, voltage and active power flow oscillations which are related to the presence of inter-area oscillations mode), and also, the minimization of their peak values during transients. The tests were realized in a two-area four-machine power system, and the results show the proposed control scheme presents a good performance for several different operating points.
Supplementary Figure 2 from SOX9 Defines Distinct Populations of Cells in SHH Medulloblastoma but Is Not Required for Math1-Driven Tumor Formation (2023)

&lt;p&gt;S2. Math1CrePtchlox/Ptchlox;Math1 GFP mice display GFP expression in the majority of tumour cells&lt;/p&gt;
A reflective color STN‐LCD with a single polarizer and double retardation films (1999)

Abstract— A reflective color STN‐LCD with a single polarizer and double retardation films has been investigated. The double retardation films arranged in front of the LC layer enabled the LCD to contain reflective electrodes inside the panel. This configuration achieves a bright image with no parallax. A new construction of a reflective STN‐LCD with a single polarizer has been developed by means of our own method in which the color difference Δ E * as the optimizing parameter has been used. Further, RGB color filters have been newly designed for our reflective LCD, and an aluminum (Al) layer has been introduced as a reflective electrode. As a result, we have realized a 7.8‐in.‐diagonal reflective color STN‐LCD (640 × 480) which has 15% reflectance, 14:1 contrast ratio, 4096‐color capability, and sufficient color gamut. It has been confirmed that the single‐polarizer reflective color STN‐LCD has sufficient performance for mobile business tools. We believe that it will be a key device for this application.
Total Synthesis of Natural and Unnatural Lamellarins with Saturated and Unsaturated D-Rings (2006)

Twenty-eight natural and unnatural lamellarins with either a saturated or an unsaturated D-ring were synthesized according to our developed synthetic route. The key step involved the Michael addition/ring closure (Mi-RC) of the benzyldihydroisoquinoline and alpha-nitrocinnamate derivatives, which provided the 2-carboethoxypyrrole intermediates in moderate to good yields (up to 78% yield). Subsequent hydrogenolysis/lactonization furnished lamellarins with a saturated D-ring in excellent yields (up to 93% yield). DDQ oxidation of the saturated lamellarin acetates led directly to the corresponding unsaturated analogues in 54-95% yield. In addition, only two steps in our developed strategy require column chromatography.
Reliability-Based Framework for Damage Prognosis of Adhesively-Bonded Joints in Composite UAV Wings (2010)

The extensive use of lightweight composite materials in unmanned aerial vehicles (UAVs) drastically increases the sensitivity to both fatigue- and impact-induced damage of their critical structural components. The skin-to-spar adhesive joints are considered one of the most fatigue sensitive subcomponents of a lightweight composite UAV wing with the damage progressively evolving from the wing root. Therefore, a system capable of monitoring these joints, assessing the structural integrity of the wing, identifying a condition-based maintenance, and predicting the remaining life (damage prognosis) is ultimately needed. In contribution to this goal, the paper presents the theoretical development of a novel probabilistic methodology for predicting the remaining service life of adhesively-bonded joints in composite UAV wings. Non-destructive evaluation techniques and Bayesian inference are used to (i) assess the current state of damage and, (ii) update the probability distribution of the damage extent at various locations. A probabilistic model for future aerodynamic loads—turbulence and maneuver induced—and a mechanics-based damage model for the adhesive interfaces are then used to propagate damage through the joints. Combined local (e.g., exceedance of a critical damage size) and global (e.g., exceedance of the flutter instability boundary) failure criteria are finally employed to compute the probability of failure at future times by abstracting the UAV wing as a series system. ∆
Electrochemical Switching of Photoelectrochemical Processes at CdS QDs and Photosystem I-Modified Electrodes (2012)

Photoactive inorganic CdS quantum dots (QDs) or the native photosystem I (PSI) is immobilized onto a pyrroloquinoline quinone (PQQ) monolayer linked to Au electrodes to yield hybrid relay/QDs (or photosystem) assemblies. By the electrochemical biasing of the electrode potential, the relay units are retained in their oxidized PQQ or reduced PQQH(2) states. The oxidized or reduced states of the relay units dictate the direction of the photocurrent (anodic or cathodic). By the cyclic biasing of the electrode potential between the values E ≥ -0.05 V and E ≤ -0.3 V vs Ag quasi-reference electrode (Ag QRE), retaining the relay units in the oxidized PQQ or reduced PQQH(2) states, the photocurrents are respectively switched between anodic and cathodic values. Different configurations of electrically switchable photoelectrochemical systems are described: (i) the PQQ/CdS QDs/(triethanolamine, TEOA) or PQQ/PSI/(ascorbic acid/dichlorophenolindophenol, DCPIP) systems, leading to anodic photocurrents; (ii) the PQQ/CdS QDs (or PSI)/(flavin adenine dinucleotide) systems, leading to cathodic photocurrents; (iii) the PQQ/CdS QDs (or PSI)/(O(2)) switchable systems, leading to cyclic anodic/cathodic switching of the photocurrents.
PANI–LDPE composites: Effect of blending conditions (2008)

Abstract A composite based on polyaniline (PANI) and low density polyethylene (LDPE) with electrical conductivity was developed. Polyaniline was polymerized by chemical oxidation and doped with dodecyl‐benzene‐sulfonic acid (DBSA). PANI–LDPE composites were prepared via melt blending and the films were obtained by compression molding. The influence of three variables of the blending (temperature, [PANI], rotor speed) on conductivity, microstructure and mechanical properties of the composites was studied by means of statistical tools and a 2 3 experimental design. The results show that the PANI concentration is the most influential variable, which mainly affects the conductivity and the elongation at break of the composites. These changes are related to the microstructure of the composites. Statistically, the other variables don't show significant influence on conductivity and mechanical properties in the studied range. POLYM. COMPOS., 2009. © 2008 Society of Plastics Engineers.
A robust registration method for real-time ultrasound image fusion with pre-acquired 3D dataset (2011)

In recent years real-time ultrasound (US) image fusion with pre-acquired 3D dataset has become widely used in both diagnosis and image-guided interventions. The accuracy of a US image fusion system heavily depends on the image registration method. However, the registration procedure of this application is inevitably interfered by possible outliers in the corresponding point pairs. This is either caused by image feature difference between two modalities or by tissue shifting and deformation of patient body between two imaging studies. While traditional methods often ignore the position error of registration points, we present a random sample consensus-based algorithm to reduce the impact of outliers and improve the robustness. To evaluate our algorithm, a simulation study is carried out, and the new method is compared with state-of-the-art, least square (LS) method. It is shown that our new method is comparable with LS method under non-outlier condition, but it performs significantly better when outliers exist.
PNAS-2: A Novel Gene Probably Participating in Leukemogenesis (2006)

Based on the preliminary data, we suggest that the PNAS-2 gene functions as an anti-apoptotic gene and probably participates in leukemogenesis.
The 2D-S (Stereo) Probe: Design and Preliminary Tests of a New Airborne, High-Speed, High-Resolution Particle Imaging Probe (2006)

Abstract The design, laboratory calibrations, and flight tests of a new optical imaging instrument, the two-dimensional stereo (2D-S) probe, are presented. Two orthogonal laser beams cross in the middle of the sample volume. Custom, high-speed, 128-photodiode linear arrays and electronics produce shadowgraph images with true 10-μm pixel resolution at aircraft speeds up to 250 m s−1. An overlap region is defined by the two laser beams, improving the sample volume boundaries and sizing of small (&amp;lt;∼100 μm) particles, compared to conventional optical array probes. The stereo views of particles in the overlap region can also improve determination of three-dimensional properties of some particles. Data collected by three research aircraft are examined and discussed. The 2D-S sees fine details of ice crystals and small water drops coexisting in mixed-phase cloud. Measurements in warm cumuli collected by the NCAR C-130 during the Rain in Cumulus over the Ocean (RICO) project provide a test bed to compare the 2D-S with 2D cloud (2D-C) and 260X probes. The 2D-S sees thousands of cloud drops &amp;lt;∼150 μm when the 2D-C and 260X probes see few or none. The data suggest that particle images and size distributions ranging from 25 to ∼150 μm and collected at airspeeds &amp;gt;100 m s−1 by the 2D-C and 260X probes are probably (erroneously) generated from out-of-focus particles. Development of the 2D-S is in its infancy, and much work needs to be done to quantify its performance and generate software to analyze data.
Retinal Degeneration 3 (RD3) Protein Inhibits Catalytic Activity of Retinal Membrane Guanylyl Cyclase (RetGC) and Its Stimulation by Activating Proteins (2011)

Retinal membrane guanylyl cyclase (RetGC) in the outer segments of vertebrate photoreceptors is controlled by guanylyl cyclase activating proteins (GCAPs), responding to light-dependent changes of the intracellular Ca(2+) concentrations. We present evidence that a different RetGC binding protein, retinal degeneration 3 protein (RD3), is a high-affinity allosteric modulator of the cyclase which inhibits RetGC activity at submicromolar concentrations. It suppresses the basal activity of RetGC in the absence of GCAPs in a noncompetitive manner, and it inhibits the GCAP-stimulated RetGC at low intracellular Ca(2+) levels. RD3 opposes the allosteric activation of the cyclase by GCAP but does not significantly change Ca(2+) sensitivity of the GCAP-dependent regulation. We have tested a number of mutations in RD3 implicated in human retinal degenerative disorders and have found that several mutations prevent the stable expression of RD3 in HEK293 cells and decrease the affinity of RD3 for RetGC1. The RD3 mutant lacking the carboxy-terminal half of the protein and associated with Leber congenital amaurosis type 12 (LCA12) is unable to suppress the activity of the RetGC1/GCAP complex. Furthermore, the inhibitory activity of the G57V mutant implicated in cone-rod degeneration is strongly reduced. Our results suggest that inhibition of RetGC by RD3 may be utilized by photoreceptors to block RetGC activity during its maturation and/or incorporation into the photoreceptor outer segment rather than participate in dynamic regulation of the cyclase by Ca(2+) and GCAPs.
Isoquinoline and peripheral-type benzodiazepine binding in gliomas: implications for diagnostic imaging. (1988)

Binding of the isoquinoline PK 11195 and of the benzodiazepines Ro5-4864 and flunitrazepam was compared in glioma cells and tissues. In human and rat glioma cell cultures [3H]PK 11195 bound with higher affinity (Kd = 14.01 and 15.76 nM, respectively) than either Ro5-4864 (Ki = 1200 and 84.9 nM, respectively) or flunitrazepam (Ki greater than 10,000 and = 848 nM, respectively). Autoradiograms of postmortem human brain sections containing glioma revealed that [3H]PK 11195 bound specifically to intact tumor cells and not to cells of normal cerebral cortex or necrotic areas of the tumor. Total [3H]Ro5-4864 or [3H]flunitrazepam binding to these sections was indistinguishable from nonspecific binding, and regions of tumor and normal brain could not be delineated. These results support the use of radiolabeled PK 11195 for clinical trials of imaging human gliomas by positron emission tomography.
Nonlinear model predictive control of glucose concentration in subjects with type 1 diabetes (2004)

A nonlinear model predictive controller has been developed to maintain normoglycemia in subjects with type 1 diabetes during fasting conditions such as during overnight fast. The controller employs a compartment model, which represents the glucoregulatory system and includes submodels representing absorption of subcutaneously administered short-acting insulin Lispro and gut absorption. The controller uses Bayesian parameter estimation to determine time-varying model parameters. Moving target trajectory facilitates slow, controlled normalization of elevated glucose levels and faster normalization of low glucose values. The predictive capabilities of the model have been evaluated using data from 15 clinical experiments in subjects with type 1 diabetes. The experiments employed intravenous glucose sampling (every 15 min) and subcutaneous infusion of insulin Lispro by insulin pump (modified also every 15 min). The model gave glucose predictions with a mean square error proportionally related to the prediction horizon with the value of 0.2 mmol L(-1) per 15 min. The assessment of clinical utility of model-based glucose predictions using Clarke error grid analysis gave 95% of values in zone A and the remaining 5% of values in zone B for glucose predictions up to 60 min (n = 1674). In conclusion, adaptive nonlinear model predictive control is promising for the control of glucose concentration during fasting conditions in subjects with type 1 diabetes.
Urban Surface Water Management (1989)

Fundamentals of Urban Surface Water Management. The Hydrologic Cycle in the Urban Environment. Techniques for Hydrologic Analyses. Floodplain Hydraulics. Stormwater Facility Hydraulics. Computation of Average Annual Monetary Flood Damage. Nonpoint--Source Pollution Load Techniques. Planning and Designing Detention/Retention Facilities. Sedimentation Basin Design. Computer Modeling. Management Measures. Preparation of a Master Plan. Appendices. Index.