gebhart/patrepeval huggingface dataset:
Preliminary exploration of the measurement of walking speed for the apoplectic people based on UHF RFID (2015)

The number of the apoplectic people is increasing while population aging is quickening its own pace. The precise measurement of walking speed is very important to the rehabilitation guidance of the apoplectic people. The precision of traditional measuring methods on speed such as stopwatch is relatively low, and high precision measurement instruments because of the high cost cannot be used widely. What's more, these methods have difficulty in measuring the walking speed of the apoplectic people accurately. UHF RFID tag has the advantages of small volume, low price, long reading distance etc, and as a wearable sensor, it is suitable to measure walking speed accurately for the apoplectic people. In order to measure the human walking speed, this paper uses four reader antennas with a certain distance to reads the signal strength of RFID tag. Because RFID tag has different RSSI (Received Signal Strength Indicator) in different distances away from the reader, researches on the changes of RSSI with time have been done by this paper to calculate walking speed. The verification results show that the precise measurement of walking speed can be realized by signal processing method with Gaussian Fitting-Kalman Filter. Depending on the variance of walking speed, doctors can predict the rehabilitation training result of the apoplectic people and give the appropriate rehabilitation guidance.
Quantum State Transfer and Entanglement Distribution among Distant Nodes in a Quantum Network (1997)

We propose a scheme to utilize photons for ideal quantum transmission between atoms located at spatially separated nodes of a quantum network. The transmission protocol employs special laser pulses that excite an atom inside an optical cavity at the sending node so that its state is mapped into a time-symmetric photon wave packet that will enter a cavity at the receiving node and be absorbed by an atom there with unit probability. Implementation of our scheme would enable reliable transfer or sharing of entanglement among spatially distant atoms.
Repetitive Transcranial Magnetic Stimulation-Induced Changes in Sensorimotor Coupling Parallel Improvements of Somatosensation in Humans (2006)

Repetitive transcranial magnetic stimulation (rTMS) is an established technique for non-invasive stimulation of human cortex. Although studies have shown an influence of rTMS on single cortical regions and on simple behavioral response patterns, its influences on the dynamics of task-related activity in cortical networks have not been characterized. We provide such a characterization by showing that 5 Hz rTMS over primary somatosensory cortex (SI) induces a reconfiguration of activity patterns in a sensorimotor network, comprising the stimulated region and ipsilateral primary motor cortex (MI). These plastic changes endure for up to 120 min and are correlated with behavioral improvement in discrimination. Dynamic causal modeling showed that this reconfiguration could be explained by an rTMS-induced increase in SI excitability (self-connection) and an increase in the effective connectivity from SI to MI. Thus, our data demonstrate that rTMS can temporarily induce behaviorally relevant reorganization within a complex cortical network underlying human somatosensory experience.
Structure-activity relationship of 1-desamino-8-D-arginine vasopressin as an antiproliferative agent on human vasopressin V2 receptor-expressing cancer cells (2014)

The synthetic nonapeptide 1‑desamino‑8‑D‑arginine vasopressin (dDAVP) can reduce tumor cell growth through agonist action on the vasopressin V2 receptor. A structure‑antiproliferative activity relationship analysis of dDAVP was performed using the alanine scanning technique on the aggressive MDA‑MB‑231 human breast carcinoma cell line. The results from this analysis demonstrated that the amino acids located at the loop of dDAVP are important for the antiproliferative activity of dDAVP, highlighting the key role of the N‑terminal region of the peptide in the interaction with the tumor cell surface receptor. The findings from this study present novel strategies for designing improved compounds with enhanced stability for cancer therapy.
Non binary LDPC codes over the binary erasure channel: Density evolution analysis (2008)

In this paper we present a thorough analysis of non binary LDPC codes over the binary erasure channel. First, the decoding of non binary LDPC codes is investigated. The proposed algorithm performs ldquoon-the flyrdquo decoding, i.e. it starts decoding as soon as the first symbols are received, which generalizes the erasure decoding of binary LDPC codes. Next, we evaluate the asymptotical performance of ensembles of non binary LDPC codes, by using the density evolution method. Density evolution equations are derived by taking into consideration both the irregularity of the bipartite graph and the probability distribution of the graph edge labels. Finally, infinite-length performance of some ensembles of non binary LDPC codes for different edge label distributions are shown.
Apolipoprotein B metabolism in subjects with deficiency of apolipoproteins CIII and AI. Evidence that apolipoprotein CIII inhibits catabolism of triglyceride-rich lipoproteins by lipoprotein lipase in vivo. (1986)

Previous data suggest that apolipoprotein (apo) CIII may inhibit both triglyceride hydrolysis by lipoprotein lipase (LPL) and apo E-mediated uptake of triglyceride-rich lipoproteins by the liver. We studied apo B metabolism in very low density (VLDL), intermediate density (IDL), and low density lipoproteins (LDL) in two sisters with apo CIII-apo AI deficiency. The subjects had reduced levels of VLDL triglyceride, normal LDL cholesterol, and near absence of high density lipoprotein (HDL) cholesterol. Compartmental analysis of the kinetics of apo B metabolism after injection of 125I-VLDL and 131I-LDL revealed fractional catabolic rates (FCR) for VLDL apo B that were six to seven times faster than normal. Simultaneous injection of [3H]glycerol demonstrated rapid catabolism of VLDL triglyceride. VLDL apo B was rapidly and efficiently converted to IDL and LDL. The FCR for LDL apo B was normal. In vitro experiments indicated that, although sera from the apo CIII-apo-AI deficient patients were able to normally activate purified LPL, increasing volumes of these sera did not result in the progressive inhibition of LPL activity demonstrable with normal sera. Addition of purified apo CIII to the deficient sera resulted in 20-50% reductions in maximal LPL activity compared with levels of activity attained with the same volumes of the native, deficient sera. These in vitro studies, together with the in vivo results, indicate that in normal subjects apo CIII can inhibit the catabolism of triglyceride-rich lipoproteins by lipoprotein lipase.
The proteasome inhibitor bortezomib affects osteoblast differentiation in vitro and in vivo in multiple myeloma patients (2007)

The proteasome inhibitor bortezomib may increase osteoblast-related markers in multiple myeloma (MM) patients; however, its potential osteoblastic stimulatory effect is not known. In this study, we show that bortezomib significantly induced a stimulatory effect on osteoblast markers in human mesenchymal cells without affecting the number of osteoblast progenitors in bone marrow cultures or the viability of mature osteoblasts. Consistently we found that bortezomib significantly increased the transcription factor Runx2/Cbfa1 activity in human osteoblast progenitors and osteoblasts without affecting nuclear and cytoplasmatic active beta-catenin levels. Consequently a stimulatory effect of bortezomib on bone nodule formation was also demonstrated in osteoblast progenitors. These in vitro observations were confirmed in vivo by the finding of a significant increase in the number of osteoblastic cells x mm(2) of bone tissue and in the number of Runx2/Cbfa1-positive osteoblastic cells that was observed in MM patients who responded to bortezomib. Our in vitro and in vivo observations support the hypothesis that a direct stimulatory effect on bone formation process could occur during bortezomib treatment.
Anaerobic Oxidation of Ethene Coupled to Sulfate Reduction in Microcosms and Enrichment Cultures (2013)

Ethene is considered recalcitrant under anaerobic conditions, but biological reduction to ethane and oxidation to CO2 have been reported; however, little is known about these processes or the organisms carrying them out. In this report we describe sulfate dependent ethene consumption in microcosms prepared with sediments from a freshwater canal. A first dose of 0.6 mmol/L ethene was consumed within 77 days, and a second dose was largely consumed twelve days later. Material from this microcosm was transferred into growth medium with ethene as the only electron donor (except for trace amounts of vitamins) and sulfate as the electron acceptor. Four doses of ethene were consumed at increasing rates, and the cultures have been transferred at least eight times in this medium. Conversion of [(14)C]ethene primarily to (14)CO2 was demonstrated in fifth and sixth generation cultures, as well as production of sulfide in other cultures, confirming the ethene/sulfate couple. Ovoid cells 1-2 μm in diameter were found in cultures containing ethene and sulfate, and quantitative PCR showed large increases in bacterial 16S rRNA gene copy number. Over half of a 16S rRNA gene clone library from a sixth-generation culture was a phylotype with a sequence ca. 90% identical with a clade of Deltaproteobacteria that includes Desulfovirga adipica and several Syntrophobacter spp. These studies have solidified the concept that deficits in mass balances for chloroethene fate in sulfate reducing zones of contaminated groundwater sites may be due to ethene oxidation, and suggest a unique phylotype is involved in this process.
Impact of rituximab therapy for treatment of acute humoral rejection (2009)

Addition of rituximab improved the outcomes of PP treatment of antibody mediated rejection episodes.
Rice Starch–Based Sponge for Use as Topical Hemostatic Agent (2019)

The topical hemostatic agents in surgery are biomaterials that very important for surgeons to stop bleeding in the complicated areas. Currently available hemostatic agents are often expensive, ineffective or raise safety concerns. Synthetic rice starch-based sponge was an inexpensive and promising alternative. In this study, we synthesized and characterized a new hemostatic agent from rice starch and investigated their use as a hemostatic material. The rice starch-based sponge having interconnected pore were synthesized via blending of the rice starch and additive of carboxymethylcellulose (CMC), polyvinyl alcohol (PVA), and glycerol in hot water, freezing and drying by vacuum sublimation with enlarged porosity and rapid swelling behavior. Characteristics of the final products were then investigated by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and scanning electron microscopy (SEM-EDS). In vivo studies using 4 rabbits with liver injury showed rice starch-based sponge blood aggregate formation as well as bulk blood coagulation inhibition. The biocompatibility tests showed that this sponge is safe and effective after follow-up for at least 6 months of animal and clinical trial.
Degrading Mechanism on Hydrogen Absorbing-Desorbing Cycle Durability of V- and Ti-Cr-Based BCC-Type Solid Solutions (2005)

V- and Ti-Cr-based solid solutions with body-centered cubic (BCC) type structure were investigated on hydrogen absorbing-desorbing cycle durability by using H2 without and with 10ppm CO (Hereafter they are expressed as H2 and CO/H2, respectively.). The solid solutions showed excellent cycle durability even after 1,000 cycles of hydrogen absorption and desorption under H2 atmosphere. On the other hand, the capacities decreased rapidly during hydrogen absorbing-desorbing cycles in the beginning of the tests under CO/H2 one. The solutions were not disproportionate though the stable monohydride phase increased, that is, stored hydrogen increased gradually. It was observed that not only microscopic pulverization but also nanoscopically fine-grained crystallization occurred in degraded particles. It is considered that the impurity CO influences bulk structure as an intrinsic factor as well as surface area as an extrinsic factor as regarded as ever. This causes the degradation of the cycle capacities.
ChemInform Abstract: ISOLATION AND CHARACTERIZATION OF PYRIMIDINE‐PSORALEN‐PYRIMIDINE PHOTODIADDUCTS FROM DNA (1983)

Abstract Die Psoralenderivate (I) vermögen mit DNA Diaddukte zu bilden, die zur Verknüpfung zweier DNA‐Stränge fuhren.
NPM1 Deletion Is Associated with Gross Chromosomal Rearrangements in Leukemia (2010)

NPM1/5q35 deletion is a consistent event in MDS/AML with a 5q-/-5 in complex karyotypes. NPM1 deletion and NPM1 exon 12 mutations appear to be mutually exclusive and are associated with two distinct cytogenetic subsets of MDS and AML.
Beyond Politics (2017)

Private sector action provides one of the most promising opportunities to reduce the risks of climate change, buying time while governments move slowly or even oppose climate mitigation. Starting with the insight that much of the resistance to climate mitigation is grounded in concern about the role of government, this books draws on law, policy, social science, and climate science to demonstrate how private initiatives are already bypassing government inaction in the US and around the globe. It makes a persuasive case that private governance can reduce global carbon emissions by a billion tons per year over the next decade. Combining an examination of the growth of private climate initiatives over the last decade, a theory of why private actors are motivated to reduce emissions, and a review of viable next steps, this book speaks to scholars, business and advocacy group managers, philanthropists, policymakers, and anyone interested in climate change.
A8404 Anti-inflammatory activity of secreted APE1/Ref-1 in vascular endothelial cells (2018)

Objectives: Apurinic apyrimidinic endonuclease 1/Redox factor-1 (APE1/Ref-1) is a multifunctional protein that plays a DNA repair and redox regulation with secretory activity. The aim of this study was to evaluate the biological role of extracellular APE1/Ref-1 in human cultured endothelial cells. Methods: Intracellular acetylation is induced by the incubation of trichostatin A, secreted APE1/Ref-1 is quantified with sandwich ELISA. Results: During treatment of trichostatin A in culture, a time-dependent increase in secreted APE1/Ref-1 was confirmed. Trichostatin A significantly suppressed vascular cell adhesion molecule-1 expression in response to TNF-α. The acetyl moiety of acetylated-APE1/Ref-1 was rapidly removed based on the removal kinetics. Additionally, recombinant human APE1/Ref-1 with reducing activity induced a conformational change in rhTNF-α receptor 1 by thiol-disulfide exchange. Following treatment with the neutralizing anti-APE1/Ref-1 antibody, inflammatory signals via the binding of TNF-α to TNFR1 were remarkably recovered, leading to up-regulation of reactive oxygen species generation and VCAM-1. Conclusion: Furthermore, rhAPE1/Ref-1 inhibited VCAM-1 expression in interleukin-1β-stimulated endothelial cells, and inhibited inducible nitric oxide synthase. These results strongly indicate that anti-inflammatory effects in TNF-α-stimulated endothelial cells by acetylation are tightly linked to secreted APE1/Ref-1, which inhibits inflammatory cytokines binding to its receptors.
Fabricação de tijolos modulares de solo-cimento por prensagem manual com e sem adição de sílica ativa (2003)

\n Neste trabalho, por meio de uma metodologia experimental foram analisados vários aspectos de tijolos modulares compostos por misturas binárias e ternárias de solo-cimento e solo cimento-sílica produzidos em prensa manual modelo SAHARA, com a finalidade de se obter parâmetros e diretrizes que visam um melhor desempenho do material. Realizaram-se ensaios em corpos-de-prova cilíndricos de maneira acessória no decorrer do trabalho, o que resultou no suporte para fundamentação de diversas avaliações sobre as composições de traços utilizados na fabricação dos tijolos. Foram executados painéis de parede com o objetivo de verificar o comportamento da alvenaria em relação à resistência à compressão e à deformabilidade das paredes, possibilitando correlações com os resultados dos ensaios de prismas, tijolos e argamassa de assentamento. As contribuições da pesquisa permitem relacionar a tecnologia da fabricação de tijolos de solo-cimento com o contexto de construção sustentável e o aproveitamento de resíduos industriais, além de sistematizar informações para a elaboração de um projeto tecnológico com os tijolos modulares\n
Cholesterol crystallization in model biles: effects of bile salt and phospholipid species composition (2001)

Cholesterol in human bile is solubilized in micelles by (relatively hydrophobic) bile salts and phosphatidylcholine (unsaturated acyl chains at sn-2 position). Hydrophilic tauroursodeoxycholate, dipalmitoyl phosphatidylcholine, and sphingomyelin all decrease cholesterol crystal-containing zones in the equilibrium ternary phase diagram (van Erpecum, K. J., and M. C. Carey. 1997. Biochim. Biophys. Acta. 1345: 269-282) and thus could be valuable in gallstone prevention. We have now compared crystallization in cholesterol-supersaturated model systems (3.6 g/dl, 37 degrees C) composed of various bile salts as well as egg yolk phosphatidylcholine (unsaturated acyl chains at sn-2 position), dipalmitoyl phosphatidylcholine, or sphingomyelin throughout the phase diagram. At low phospholipid contents [left two-phase (micelle plus crystal-containing) zone], tauroursodeoxycholate, dipalmitoyl phosphatidylcholine, and sphingomyelin all enhanced crystallization. At pathophysiologically relevant intermediate phospholipid contents [central three-phase (micelle plus vesicle plus crystal-containing) zone], tauroursodeoxycholate inhibited, but dipalmitoyl phosphatidylcholine and sphingomyelin enhanced, crystallization. Also, during 10 days of incubation, there was a strong decrease in vesicular cholesterol contents and vesicular cholesterol-to-phospholipid ratios (approximately 1 on day 10), coinciding with a strong increase in crystal mass. At high phospholipid contents [right two-phase (micelle plus vesicle-containing) zone], vesicles were always unsaturated and crystallization did not occur. Strategies aiming to increase amounts of hydrophilic bile salts may be preferable to increasing saturated phospholipids in bile, because the latter may enhance crystallization.
Optimization of biogas residue mixed with livestock manure co-composting using response surface methodology. (2012)

According to principal components analysis,a comprehensive evaluation function was built with WSC/WSN,E4/E6,NH4+-N/NO3--N,GI,and the comprehensive evaluation value F used for the assessment of co-compost maturity was obtained on the basis of this evaluation function.In order to get the optimal proportion of biogas residue mixed with livestock manure co-composting,choosing F value as the response value and amount of biogas residue,pig manure,and chicken manure as the three factors,fifteen composting experiments were designed using Box-Behnken,and a second order polynomial equation was established.The results showed,the significant differences between the response value F and livestock manure amount was as follows: chicken manure﹥biogas residue﹥pig manure.Linear term of chicken manure amount and quadratic term of anaerobic digestion residue amount both reached extremely significant level(P0.01).Interaction term of biogas residue amount,chicken manure amount and quadratic term of chicken manure amount reached significant level(P0.05).The optimized proportion of co-compost was: the biogas residue amount 5.83kg,the pig manure amount 7.95kg,and the chicken manure amount 7.54kg.Therefore,it is reasonable that response surface method was used for optimization of material proportion of co-compost.
Effectiveness of Repair Methods of Corroded Bridge Cables (2009)

&lt;p&gt;Cables and hangers of old suspension bridges and stays of cable-stayed bridges often suffer from steel corrosion. It is important to repair them by proper methods so that corrosion does not progress further. In this paper six repair methods were proposed and applied to cable specimens. Then, the specimens were exposed to the severe corrosion environments and effectiveness of the proposed repair methods was compared. Two different types of test cables were used in this study.&lt;/p&gt;&lt;p&gt;The first test group used parallel wire strand cables consisting of 19 non-galvanized steel wires. This aimed at the main cables of suspension bridges. Six repair methods were applied to these cables: coating with zinc or epoxy resin paint or zinc powder paste, filling with epoxy resin or oil, and dehumidification method, and so on. Then the specimens were wrapped with wet gauze and kept at 40oC for 15 months. By investigating mass loss due to corrosion and appearance during this period, effectiveness of six repair methods was compared. As for the surface wires the dehumidification method was the most effective followed by the epoxy resin paint and filling, the zinc powder paste, and the zinc and epoxy resin paint. The oil filling was not very effective compared with other repair methods.&lt;/p&gt;&lt;p&gt;The second group test used spiral strand cables consisting of seven galvanized steel wires. This test aimed at hangers of suspension bridges and stays of cable-stayed bridges. The same repair methods and corrosion acceleration methods were used as the first test. By investigating mass loss due to corrosion and appearance of both inside and surface wires during the 16 month period, the proposed six repair methods were all very effective compared with no repair strands.&lt;/p&gt;&lt;p&gt;This study proves that, even if a cable is corroded, proper repair works are effective in preventing further corrosion.&lt;/p&gt;
Heterogeneous Integration for HPC and Data Centers (2019)

Abstract Invited Session on HETEROGENEOUS INTEGRATION ROADMAP - Heterogeneous Integration for HPC and Data Centers. This TWG focuses on the system-level implications related to performance, power management, security, power distribution issues and others
Self-Modulation Instability of Electron Beams in Plasma Channels of Variable Length (2019)

The self-modulation instability (SMI) of long (in respect to the plasma wavelength) charged particle beams passing through plasma enables the use of currently existing high energy charged particle beams as drivers for plasma wakefield accelerators. At the Photo Injector Test facility at DESY in Zeuthen (PITZ) the SMI of electron beams is studied *, **. An enhanced experimental setup includes a plasma channel of variable length which allows to investigate in details the development stages of the SMI by measuring the instability growth rate and phase velocity as a function of propagation distance in the plasma. In this contribution we present the experimental setup improvements, first measurement results and supporting beam dynamics simulations.