gebhart/patrepeval huggingface dataset:
Absorption Of NMR Signals At High Frequencies In Physiological Phantoms (1984)

In magnetic resonance (MR) imaging, improved signal to noise ratio (S/N) can be achieved with higher magnetic field strength. Such improvement, however, will be limited eventually by the absorption of the radiofrequency (rf) within the patient. Radiofrequency propagation into an infinite cylinder of physiological dielectric properties has been calculated at frequencies from 1 to 100 MHz for a concentric single loop antenna. The amplitude of the rf wave at the center of the phantom can be either enhanced or attenuated depending on the dielectric properties of the phantom. Measurements performed at 25 MHz in a 28-cm diameter cylindrical phantom of 154 mM saline show an attenuation of 16% and a phase shift of 57° which agree well with the calculations for this medium.
Nonauditory Effects of Noise on Behavior and Health (1981)

This article presents an overview of research and theory on the nonauditory effects of noise on human behavior and health. Laboratory and naturalistic research on the effects of noise on human performance, interpersonal behavior, annoyance, cognitive development, and mental and physical health are reviewed. The review includes studies of children as well as adults, and the discussion emphasizes the relevance of this research for predicting the effect of noise in community and industrial settings. Noise effects are viewed as determined by variations in psychological characteristics of a situation as well as the physical parameters of the sound. Predictability and controllability of a noise, its meaning for the respondent and its degree of interference with auditory communication are factors that mediate the effects of noise across a variety of outcome measures.
Nanocristaux fluorescents et magnétiques bioactivables pour le suivi de récepteurs biologiques et le ciblage de membranes (2007)

Communication orale
Gas Chromatographic and Mass Spectrometric Analysis of Samples from a Clandestine Laboratory Involved in the Synthesis of Ecstacy from Sassafras Oil (1991)

Journal Article Gas Chromatographic and Mass Spectrometric Analysis of Samples from a Clandestine Laboratory Involved in the Synthesis of Ecstacy from Sassafras Oil Get access F.T. Noggle, Jr., F.T. Noggle, Jr. Alabama Department of Forensic Sciences, Wire Road, Auburn, Alabama 36830 Search for other works by this author on: Oxford Academic PubMed Google Scholar C. Randall Clark, C. Randall Clark Department of Pharmacal Sciences, School of Pharmacy, Auburn University, Auburn, Alabama 36849 Search for other works by this author on: Oxford Academic PubMed Google Scholar Jack DeRuiter Jack DeRuiter Department of Pharmacal Sciences, School of Pharmacy, Auburn University, Auburn, Alabama 36849 Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Chromatographic Science, Volume 29, Issue 4, April 1991, Pages 168–173, https://doi.org/10.1093/chromsci/29.4.168 Published: 01 April 1991 Article history Received: 17 October 1990 Revision received: 25 January 1991 Published: 01 April 1991
Experience from large scale use of the EuroGenomics custom SNP chip in cattle (2018)

International audience
Invitation to embarrassingly parallel computing (2008)

A surprising number of physical systems problems are well suited to “embarrassingly parallel" computations which do not require complicated algorithms or specialized hardware. As faculty and students at small institutions, we are readily incorporating parallel computing in diverse levels of our curricula and are embracing the opportunity to utilize high performance computing to do cutting edge research. We describe three typical examples: spatiotemporal patterns of one-way coupled oscillators, ray-tracing in curved spacetime, and solar escape as a three-body problem.
Sitostanol ester margarine in dietary treatment of children with familial hypercholesterolemia. (1995)

In familial hypercholesterolemia (FH) the lowering of serum cholesterol levels should be started in childhood in order to prevent coronary artery disease later in life. However, treatment of children is problematic. We studied the effects of sitostanol (3 g/day) ester dissolved in rapeseed oil margarine as a hypocholesterolemic agent in one homozygous and 14 heterozygous children with FH maintained on a low cholesterol diet for 6 weeks, using a double-blind crossover design. Absorption and synthesis of cholesterol were evaluated by measuring serum plant sterol and cholesterol precursor proportions to cholesterol by gas-liquid chromatography. The compliance was good, and the children could not distinguish by taste the two margarines without and with sitostanol ester. Sitostanol margarine significantly reduced serum total, intermediate density (IDL), and low density lipoprotein (LDL) cholesterol by 11, 26, and 15%, respectively, and increased HDL/LDL cholesterol ratio by 27%. The proportions of serum delta 8-cholestenol, lathosterol, and desmosterol were significantly increased by 36, 19, and 18%, and those of serum cholestanol, campesterol, and sitosterol were significantly decreased by 9, 42 and 29%, respectively, suggesting that cholesterol absorption was decreased and synthesis was compensatorily increased. High basal precursor sterol proportions predicted a high decrease in LDL cholesterol levels. In conclusion, partial replacement of normal dietary fat consumption by sitostanol ester margarine appears to be an effective and safe hypocholesterolemic treatment in children with FH.
Non-ideal polymerization. A new analysis and its application to vinyl chloride (1970)

A new method is presented for analyzing non-ideal polymerizations in which retardation by degradative chain transfer and primary termination participate. It involves the measurement of reaction rates ω over a wide range of rates of primary radical formation ∮. The properties of the plot of log ω against log ∮ are described; its experimental realization enables the kinetic parameters to be evaluated. This approach offers the possibilities of separating the non-ideal components and allowing their contributions to be assessed, and does not require a knowledge of the rate of the unretarded reaction. The method has been applied to the polymerization of vinyl chloride in three solvents, with initiation by AZDN (thermal and photochemical) and by the Mn2(CO)10+ CCI3COOEt system (photochemical). Non-ideality decreases in the order chlorobenzene, tetrahydrofuran, ethylene dichloride; in each case the kinetic parameters have been calculated. Primary termination is significant at higher rates of initiation by AZDN; with manganese carbonyl initiation it is much less. Our treatment is shown to offer a satisfactory explanation of results obtained by other workers. The geometric mean assumption does not agree well with our observations, particularly those on polymer molecular weights.
The circular RNA Ataxia-telangiectasia mutated ( cATM ) regulates oxidative stress in smooth muscle cells in expanding abdominal aortic aneurysms (2022)

ABSTRACT An abdominal aortic aneurysm (AAA) is a pathological widening of the aortic wall characterized by loss of smooth muscle cells (SMCs), extracellular matrix degradation, and local inflammation. This condition is often asymptomatic until rupture occurs, leading to high morbidity and mortality rates. Diagnosis is often accidental, and for now, the only available treatment option remains surgical intervention. Circular RNAs (circRNAs) are RNA loops that originated from backsplicing, which have received increasing attention as a novel class of functional non-coding RNAs contributing to cardiovascular physiology and disease. Their high structural stability, combined with a remarkable enrichment in body fluids, make circRNAs promising disease biomarkers. We aimed to investigate the contribution of circRNAs to AAA pathogenesis and their potential application as biomarkers for AAA diagnosis. Combined circRNA array and quantitative real-time PCR analysis revealed the presence of differentially expressed circular transcripts stemming from AAA-relevant gene loci . Among these, the circRNA to the Ataxia-telangiectasia mutated gene (c ATM ) was upregulated in human AAA tissue specimens, in AAA patient-derived SMCs, and serum samples collected from aneurysm patients. In control primary aortic SMCs, c ATM increased upon angiotensin II stimulation, while its silencing triggered apoptosis. Furthermore, doxorubicin could induce cATM expression, supporting a link with acute stress response in SMCs. Constitutively higher c ATM expressing AAA patient-derived SMCs were less vulnerable to oxidative stress-induced cell death and survival pathways enriched when compared to control SMCs. Taken together, this data supports the role of cATM in adapting SMCs to oxidative stress in the vascular AAA micromilieu. This molecular signature provides an additional parameter to be included in procedures for AAA screening in combination with already established practices.
Allergic Asthma : What Have We Learned from the Mouse Model? (2005)

Despite advances and introduction of new and effective anti-asthma therapies, including inhaled corticosteroids and leukotriene modifiers, the mortality and morbidity of asthma is still a worldwide concern. Moreover, asthma is a complex disease (more likely a syndrome) in terms of varied pathogenesis and a marked clinical and pathological heterogeneity. To overcome the clinical limitations in investigating and unraveling this complexity, animal models have been utilized. In many ways, these models have contributed to the clarification of some of the pathogenesis and identified new therapeutic targets for drug development. We have characterized a number of such mouse models of allergic airway inflammation and altered airway function, defining the role of various cells and factors such as mast cells, interleukin (IL)-13 and CD8 + T cells in the development of airway hyperresponsiveness (AHR) and allergic airway inflammation. In these models we demonstrated that mast cells play a role in the development of AHR through stimulation of immunoglobulin receptors (FcRs). Histamine, a potent chemical mediator secreted by mast cells, was shown to contribute to the development of AHR and airway allergic inflammation. In addition, IL-13 was shown to play a critical role in these allergic responses in the lung. To date, CD8 + T cells have not been recognized as much as CD4 + T cells in the pathogenesis of allergic disorders. However, we have recently shown that CD8 + T cells, particularly allergen-primed CD8 + T cells, were potent inducers of IL-13, AHR and allergic airway inflammation. Furthermore, a subset of CD8 + T cells (T effector ; Teff) was shown to be important in the development of AHR, allergic inflammation and IL-13. Although further investigations are necessary to fully understand the complex interactions between these inflammatory cells, mediators, cytokines and chemokines, these findings provide new insights into the initiation and persistence of asthma and hopefully will lead to new therapeutic strategies for the treatment of asthma.
Rovibrational state-selected study of H2+ (X,ν+=0–17, N+=1)+Ar using the pulsed field ionization-photoelectron-secondary ion coincidence scheme (2003)

A high-resolution pulsed field ionization photoelectron-secondary ion coincidence (PFI-PESICO) method has been developed for absolute cross section measurements of state-selected ion–molecule reactions. Employing this new PFI-PESICO scheme, we have measured rovibrational-state-selected absolute cross sections for the reaction of H2+(X,ν+=0–17, N+=1)+Ar at the center-of-mass collision energies of 1.1 and 2.4 eV. The ν+=17 state is the second to the last vibrational level of H2+(X), which lies a mere 0.03 eV below the H2+(X) dissociation limit. The absolute cross sections observed for the formation of Ar+ and ArH+ [σv+(Ar++ArH+)] from H2+(X,ν+=0–4, N+=1) are consistent with previous experiments, exhibiting strong enhancement of the reaction cross section for ν+=2. However, the σv+(Ar++ArH+) values for H2+(X,ν+=5–14, N+=1)+Ar are found to be nearly constant. The drop in σv+(Ar++ArH+) observed for H2+(X,ν+=15–17, N+=1)+Ar is attributed to the further dissociation of product ArH+.
Role of ultrasonography in outcome prediction in subclinical hypothyroid patients treated with levothyroxine (2010)

Progression to overt hypothyroidism and the associated adverse effects on lipid metabolism and the cardiovascular system are major concerns for patients diagnosed with subclinical hypothyroidism (SCH). No consensus regarding the clinical parameters associated with prognosis for this mild thyroid dysfunction has yet been established, although elevation of serum anti-thyroid peroxidase antibody (TPOAb) and decreased or heterogeneous echogenicity (diffuse thyroid disease, DT) on ultrasonography (US) are commonly observed. We investigated the value of ultrasonographic examination compared to the measurement of serum TPOAb and anti-thyroglobulin antibody (TgAb) for the evaluation of levothyroxine treatment on SCH. We analyzed 204 SCH patients who initially underwent thyroid ultrasonography and were given a low dose of levothyroxine for a mean of 6.94 months. Outcome was determined by the normalization or sustained elevation of serum TSH, and evaluated according to the presence of DT on subsequent US and serum TPOAb or TgAb. Sustained TSH elevation after levothyroxine replacement was more frequent in patients who initially showed DT on US, regardless of thyroid autoantibody level. Ultrasonographic morphology had a higher negative predictive value (81.8%) compared with the absence of TPOAb (73.9%) or TgAb (73.7%) and a similar positive predictive value (48.9%) to that of thyroid autoantibodies (46.8% for TPOAb and 50.0% for TgAb) in the outcome prediction of SCH. Thyroid US may provide valuable information on the course of SCH, and DT pattern can serve as a prognostic factor when combined with other known parameters.
Effects of carbon monoxide on the brain may be mediated by nitric oxide (1996)

Carbon monoxide (CO) is known to be a toxic molecule due to the high affinity of hemoglobin for it. However, it has recently been shown that low doses of CO may play a physiological role. The aim of the present study was to examine processes occurring in the brain during exposure to 1,000 parts per million CO that result in an increase in cerebral blood flow (CBF) but are not accompanied by changes in oxidation metabolism. This study was carried out in awake rats with the multiprobe assembly developed in this laboratory for the simultaneous continuous measurement of CBF, intramitochondrial NADH redox levels, direct current potential, and extracellular concentrations of K+, Ca2+, and H+ as well as the electrocorticogram. Exposure to 1,000 parts per million CO in air resulted in an increased CBF without any concomitant changes in any of the other metabolic or ionic parameters measured. This indicates that tissue hypoxia was not the trigger for this vasodilation. Injection of N omega-nitro-L-arginine (L-NNA), a nitric oxide synthase inhibitor, before exposure to CO effectively blocked the increase in CBF that was observed when the animal was exposed to CO without prior injection of L-NNA. Furthermore, electrocorticographic depression was observed after the combined treatment of L-NNA and CO. In conclusion, exposure to relatively low doses of CO apparently does not have a deleterious effect on oxidative metabolism because the increase in CBF after this exposure is sufficient to prevent changes in oxidative metabolism, as indicated by the fact that NADH levels remained constant. This protective autoregulatory effect may be mediated by nitric oxide.
Investigation in Spatial-Temporal Domain for Face Spoof Detection (2018)

This paper focuses on face spoofing detection using video. The purpose is to find out the best scheme for this task in the end-to-end learning manner. We investigate 4 different types of structure to fully exploit the raw data in its spatial-temporal domain, which are the pure CNN, CNN with 3D convolution, CNN+LSTM and CNN+Conv-LSTM. Moreover, another stream built on optical flow is also used, and with a proper fusion method, it can improve the accuracy. In experiments, we compare schemes on the raw data in single stream and fusion methods with optical flow in two streams. The performance are not only given within each dataset, but also measured across different datsets, which is crucial to avoid the overfitting.
Effects of ultraviolet radiation on intercellular communication in V79 Chinese hamster fibroblasts (1994)

The effects of ultraviolet (UV) radiation on gap junctional intercellular communication (GJIC) in V79 Chinese hamster fibroblasts were studied by means of a dye transfer assay. Intercellular communication was shown to be altered by UVB (297/302 nm) and UVA (365 nm) radiation, the effect depending on the wavelength of exposure and time between irradiation and microinjection of the dye in the dye transfer assay. Exposure to 297/302 nm radiation induced a reduction in intercellular communication 6 min after exposure. Incubation of the cells post-irradiation reversed the inhibition of GJIC. From 2 to 24 h after exposure an increase in GJIC over the control cells was seen, with a maximum at 8 h post-irradiation. UVA (365 nm) radiation, on the other hand, induced an increase in the intercellular communication 6 min after irradiation. Incubation of the cells post-irradiation led to a decrease in the number of communicating cells, with a minimum seen 4 h after exposure. The reduction in communication observed after exposure to UVB and UVA was not correlated with similar modifications in the gap junction protein connexin43 as found when exposing the cells to the tumour promoter 12-O-tetradecanoyl-phorbol-13-acetate. For the higher fluences of UVA, a decrease in immunorecognizable connexin43 was seen, concomitant with a markedly increased background of higher mol. wt compounds. This may be due to UVA-induced crosslinking of connexin43. No correlation was found between changes in communication induced by UV radiation and levels of cyclic AMP.
Practical Aspects of Converting Ingot to Billet (2005)

Abstract This article describes the presses, transportation equipment, and manufacturing processes associated with cogging. It discusses the practical and metallurgical issues encountered during the conversion of ingot to billet. The article explains the use of numerical modeling as part of the continuing efforts to reduce the cost and time associated with developing new cogging sequences, increase the yield, make the processes more robust, and increase the quality of the produced product.
ChemInform Abstract: REAKTIVATOREN DER ACETYLCHOLINESTERASE 8. MITT. ABBAUREAKTIONEN AN CARBONSAEUREESTERN DER N‐METHOXY‐PYRIDINIUM‐CARBALDEHYDOXIME (1975)

Abstract Die 2‐ bzw. 4‐substituierten N‐Methoxypyridiniumcarbaldehydoximderivate (I) werden in Gegenwart von NaOH zu den Nitrilen (II) oxidiert, die auch aus den Aldoximen (III) mit Acetanhydrid in alkalischer Lösung erhalten werden.
Top−Down Approach for the Preparation of Colloidal Carbon Nanoparticles (2004)

Certain polyoxometalate anions strongly chemisorb on the surface of carbon black aggregates. Together with an ultrasound treatment, this adsorption constitutes the driving force for the splitting of initially big carbon particles into smaller units. The negative charge generated at the particle surface favors the formation of a colloidal suspension and allows the controlled generation of carbon nanoparticles.
On archiving architecture documents (2005)

This paper presents a novel perspective on archiving architecture documents in large organizations. Designing and architecting a system deals with modeling the high level structure of a system in terms of views, architectural patterns and styles. Aspects such as knowledge management and archiving of architecture work done on artifacts of software projects challenge the large organizations. Knowledge management in such organizations depends on how well the company preserves the knowledge acquired on projects and how well the company provides the facilities to retrieve that architectural knowledge. The main issue in identification of the architecture documents is how we annotate these documents while storing in the repository. We have identified an approach on how these architecture documents can be annotated with architecture properties, and provided a comprehensive search design on the architecture documents already stored in the database. We describe how this perspective offers a good solution on archiving architecture documents and outlines various issues worthy of further exploration.
High-Performance Spirulina–Bismuth Biohybrids for Enhanced Computed Tomography Imaging (2020)

The aqueous synthesis of pure bismuth nanoparticles (Bi NPs) is still challenging due to oxidative decomposition and hydrolytic instability, especially in aqueous media. This study reports the fabrication of novel high Bi content biohybrids in the presence of Spirulina platensis (SP) microalgae as biotemplate for enhanced computed tomography (CT) imaging. Rectangular microrods coated with a high content of metal Bi NPs were obtained via an one-pot chemical reduction method with minimally involved reagents in aqueous media, which could be converted to hollow microrod materials after calcination. The effect of the molar ratio of NaBH4 as a reducing agent and bismuth nitrate on the nature and morphology of the target biohybrids was fully investigated. Increasing the molar ratio of NaBH4/Bi led to the conversion of Bi2O3 to metal Bi NPs with the same morphology. The resultant biohybrid showed high physiological stability, suitable antioxidant activity, long circulation time, low toxicity, and natural degradability. Also, hemocompatibility assay revealed minor hemolytic activity of the final biohybrids. X-ray attenuation measurements and in vivo animal tests with both oral administration and intravenous injection of the biohybrid showed high CT contrast efficacy compared with those of conventional CT contrast agents. In summary, the prepared biohybrids could serve as a promising CT probe for both a functional gastrointestinal (GI) tract and intravenous injection.
Biomechanical Effect of Ferrule on Incisors Restored with a Fiberglass Post and Lithium-Disilicate Ceramic Crown after Thermal Cycling and Fatigue Loading. (2018)

The NFe group showed increased root dentin strain after the aging process. The Fe group revealed higher fracture resistance, lower stress concentration on root dentin and fewer catastrophic fractures.
Superconducting Power Cable Application in DC Electric Railway Systems (2013)

A superconducting power cable is a prospective application of high-temperature superconductors. Although power cables using Bi2223 or YBCO wires have been developed in the world so far mainly for utility grid application, we focus attention on railway application of a superconducting power cable. We have studied how to introduce superconducting power cables effectively and economically to a dc electric railway. Numerical analysis models based on the MATLAB-Simulink are constructed for a dc electric feeder system of singe- and double-track railways. Tractive force and train resistance characteristics are modeled. Energy saving by the superconducting power cable is investigated with the influences of the number of substations, the train operation interval, etc., taken into account. The results show that the superconducting power cables can improve regeneration rate and system energy saving, and reduce the substation capacity very effectively. It will be also an advantage that if the transportation capacity of a railway line needs to be increased, the introduction of superconducting cables could achieve it without changing the existing substations along the line.