gebhart/patrepeval huggingface dataset:
Indium Oxide Thin-Film Transistors Fabricated by RF Sputtering at Room Temperature (2010)

Thin-film transistors (TFTs) were fabricated using an indium oxide (In <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> ) thin film as the n-channel active layer by RF sputtering at room temperature. The TFTs showed a thickness-dependent performance in the range of 48-8 nm, which is ascribed to the total carrier number in the active layer. Optimum device performance at 8-nm-thick In <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> TFTs had a field-effect mobility of 15.3 cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> · V <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-1</sup> · s <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-1</sup> , a threshold voltage of 3.1 V, an ON-OFF current ratio of 2.2 × 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">8</sup> , a subthreshold gate voltage swing of 0.25 V · decade <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-1</sup> , and, most importantly, a normally OFF characteristic. These results suggest that sputter-deposited In <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> is a promising candidate for high-performance TFTs for transparent and flexible electronics.
Hydrogen Gas Pressure Characteristics in the snubber using CFD simulation (2007)

Hydrogen is the most promising future fuel. The compression system is one of the most important parts of hydrogen economy fuel system. To remove / lessen the pressure pulsation created during compression, snubber- a pressure pulsation damper is used. An experiment was done to investigate snubber performance and to investigate pressure characteristics in the snubber. CFD analysis was applied to find out pressure inside the snubber; as numerical analysis was same as experimental data. Initially pressure was not uniformly distributed but it was almost same except some points inside the snubber after the certain time.
Gene expression profiling in the Cynomolgus macaque Macaca fascicularis shows variation within the normal birth range (2011)

These differences in gene expression levels between animals in the upper and lower percentiles of the normal birth weight range may point towards early life metabolic adaptations that in later life result in differences in disease risk.
Role of Rab GDP dissociation inhibitor α in regulating plasticity of hippocampal neurotransmission (2000)

Rab GDP dissociation inhibitor alpha (Rab GDIalpha) is a regulator of the Rab small G proteins implicated in neurotransmission, and mutations of Rab GDIalpha cause human X-linked mental retardation associated with epileptic seizures. In Rab GDIalpha-deficient mice, synaptic potentials in the CA1 region of the hippocampus displayed larger enhancement during repetitive stimulation, which was apparently opposite to the phenotype of Rab3A-deficient mice. Furthermore, the Rab GDIalpha-deficient mice showed hypersensitivity to bicuculline, an inducer of epileptic seizures. These results suggest that Rab GDIalpha plays a specialized role in Rab3A recycling to suppress hyperexcitability via modulation of presynaptic forms of plasticity.
1,1′-OXALYLDIIMIDAZOLE, A NEW REAGENT FOR ACTIVATION OF CARBOXYLIC ACID (1983)

Abstract Carboxylic acids and their salts are converted into the 1-acylimidazoles by the title reagent. This reaction is applied for esterification of fatty acids.
Chemometrics (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChemometricsSteven D. BrownSteven D. BrownMore by Steven D. BrownCite this: Anal. Chem. 1990, 62, 12, 84–101Publication Date (Print):June 15, 1990Publication History Published online1 May 2002Published inissue 15 June 1990https://pubs.acs.org/doi/10.1021/ac00211a008https://doi.org/10.1021/ac00211a008research-articleACS PublicationsRequest reuse permissionsArticle Views309Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Robotique évolutionniste: conception orientée vers le comportement (2010)

The goal of this research is to develop a behavior oriented design methodology dedicated to mobile and autonomous robotics. The sought design methodology should start from what is known, i.e. a description of the mission to be fulfilled. Noticing that animals have a high level of autonomy that would provide to robots the ability to fulfill numerous missions, we have focused our search, in the frame of the animat approach, on the main mechanism that has built and designed living creatures: natural selection. One of the features of natural selection, is that it only takes into account the result, i.e. the ability to transmit the genes. In an artificial context, such an algorithm will take into account the ability to solve the given task. We have focused our research on the scaling problem in terms of the complexity of behaviors exhibited by evolved neuro-controllers – both structure and parameters of a neural network being generated by the evolutionary algorithm. A study on modularity has revealed us the importance of the selection pressure definition, leading to a so called exaptation approach. We propose then the use of a multi-objective scheme in which the fitness function rewarding task achievement is associated to objectives that may be independent from this goal. In this “multi-objectivization” context and besides work on exaptation, our contributions are the following: * multi-objective incremental approach: each sub-task is associated to a separate objective. It is then neither necessary to weight them, nor to choose a resolution order, nor to decide when to switch from one task to another; * behavior diversity: an objective measuring the mean distance in the space of behaviors to the rest of the population is used to maintain a high diversity in this space. This approach has led to very efficient results, even with the most simple neural network encodings; * transferability: a transferability objective is maximized to facilitate the transfer from simulation to reality without any significant performance loss. In the perspective of designing more cognitive controllers and in the frame of the ANR EvoNeuro project, we have proposed a methodological approach relying on neurosciences and consisting in generating neural networks close to models developed in this research field. On the basis of a specific neural network encoding, we have generated neural networks exhibiting simple action selection or working memory abilities. The goal of this project is to generate neural network showing other cognitive abilities studied in computational neuroscience while relying on their evaluation protocol and then applying these results in a robotic context. In this project, we have also developed a multi-objective analysis method allowing neuroscientists to compare and analyze their own models on the basis of a multi-objective optimization.
DOTAREM (DOTA)–Gold-Nanoparticles: Design, Spectroscopic Evaluation to Build Hybrid Contrast Agents to Applications in Nanomedecine (2022)

We proved that DOTA IN-CTL AuNPs have several advantages: i) Biological efficacy on three cell lines: MIA PaCa-2 (human pancreatic cancer cell line), TIB-75 (murine liver cell line) and KKU-M213 (cholangiocarcinoma cell line); ii) high stability, and no-toxicity; iii) high efficiency as a PPT agent. The study conducted on MRI in vitro and in vivo models will be suitable for diagnosis and therapy.
Percutaneous absorption: interfacial transfer kinetics (1979)

Abstract A new rotating diffusion cell is described in which a solute diffuses through a rotating filter. The transport of the solute to both sides of the filter is controlled by the rotation. The filter is filled with an organic phase. The rate of transfer of the solute through the filter is determined by the transport and by the kinetics of the interfacial transfer reactions. Since the transport is controlled the rate constant for the transfer reaction can be measured. Results for eleven different systems are reported and it is found that the rate constants are all smaller than 10−4 ms−1.
Effect of circadian clock mutations on DNA damage response in mammalian cells (2012)

The circadian clock is a global regulatory mechanism that confers daily rhythmicity on many biochemical and physiological functions, including DNA excision repair in mammalian organisms. Here, we investigated the effect of the circadian clock on the major DNA damage response pathways by using mouse cell lines mutated in genes encoding proteins in the positive (Bmal1, CLOCK) or negative (Cry 1/2, Per 1/2) arms of the transcription-translation feedback loop that generates the circadian clock. We find that cells mutated in these genes are indistinguishable from wild-type in their response to UV, ionizing radiation and mitomycin C. We conclude that either the majority of DNA damage response reactions are not controlled by the circadian clock or that, even if such a control exists at the organism level, it is supplanted by homeostatic control mechanisms at the cellular level in tissue culture. We suggest that caution must be exercised in extrapolating from experiments in tissue culture to whole animals with respect to the effect of the circadian clock on cellular response to DNA damaging agents.
Environment Simulation for the Development, Evaluation and Verification of Underlying Algorithms for Automated Driving (2016)

Algorithms for situation interpretation and prediction in traffic environments are essential in order to face automated driving challenges successfully. At the same time it is hardly possible to guarantee the functionality of such algorithms in every imaginable situation. In order to cope with such problems, the common approach in practice is to apply exhaustive and time consuming evaluation in real traffic situations. In this contribution a driving environment simulation is presented that is suited for the simulation of various highway scenarios and the generation of simulation data comparable to the output of a physical sensor data fusion architecture in real highway situations. The simulation models the dynamics of traffic flow augmented with a data based model to account for perception uncertainties. Finally a sample traffic scenario and the generated simulation output is presented.
Supplementary Table 1 and 2 from Cetuximab Resistance in Head and Neck Cancer Is Mediated by EGFR-K<sub>521</sub> Polymorphism (2023)

&lt;p&gt;Supplementary Table 1 Patient characteristics including EGFRK521 allele frequency. Supplementary Table 2 Characteristics and sequencing data of squamous cell carcinoma cell lines.&lt;/p&gt;
Infrared reflectivity and electronic states in perovskite-type oxides La1-xSrxFeO3and La1-xSrxCoO3 (1987)

Optical phonon spectra are investigated by infrared reflectivity measurements for La1-xSrxFeO3 (x=0, 0.1, 0.25 and 0.4) and La1-xSrxCoO3 (x=0, 0.02 and 0.1). Using the phonon parameters determined by Kramers-Kronig and oscillator analysis, the effective charges and the electron-phonon coupling constants are evaluated for each phonon mode. On the basis of these results, the chemical bonding and the electronic band structure of these materials are discussed. It is found that the bonding in LaCoO3 is covalent and that it is not affected by the Sr substitution. However, the bonding in LaFeO3 is rather ionic and the Sr substitution increases the degree of the covalency in this material.
A New Procedure for Stable Quantification of Endotoxin in Dialysate Fluid Using Limulus Reagent (1994)

For reliable determination of endotoxin, the activation of enzymes in lysate before measurement should be prevented, and the authors have designed a new procedure to effect this by dissolving the enzymes in lysate in a buffer solution of low pH. A given amount of the enzymes in lysate was dissolved in a lower pH buffer solution (pH 6.1-6.3) and the substrate was dissolved in a higher pH buffer solution (pH 8.0). After standing for 0-24 hr, both solutions were mixed with the sample solution. Data on blank absorbance and calibration line slope obtained by the new procedure were compared with those obtained by the conventional procedure. In the conventional procedure, blank absorbance increased with standing time, reaching approximately seven times the initial value in 24 hr, whereas in the improved procedure, it increased by 1.5 times at a standing time of 3 hr, after which it was independent of standing time. The change in slope of the calibration line with standing time was more gradual in the improved procedure than in the conventional procedure. The authors conclude that the activation of enzymes in lysate can be prevented by dissolving the enzymes in a buffer solution of low pH, and that this procedure is effective for long-term monitoring of endotoxin concentration.
Metallo-Aldehyde Enolates via Enal Hydrogenation:  Catalytic Cross Aldolization with Glyoxal Partners As Applied to the Synthesis of 3,5-Disubstituted Pyridazines (2004)

Aldehyde enolates generated through rhodium-catalyzed enal hydrogenation are subject to electrophilic trapping by exogenous glyoxal partners to afford beta-hydroxy-gamma-keto-aldehyde products, which upon exposure to hydrazine afford 3,5-disubstituted pyridazines in moderate yield in a two-step, one-pot sequence.
GROWTH HORMONE MODULATION OF ARGININE‐INDUCED GLUCAGON RELEASE: STUDIES OF ISOLATED GROWTH HORMONE DEFICIENCY AND ACROMEGALY (1978)

Plasma glucagon and insulin responses to L-arginine were compared in normal controls and patients with isolated growth hormone deficiency and acromegaly. Patients with isolated growth hormone deficiency were characterized by high plasma glucagon response and low plasma insulin response, whereas acromegalic patients showed exaggerated plasma glucagon response and almost normal insulin response. These results suggest that growth hormone is probably required for optimum function of the islets, and since hyperglucagonaemia was observed in both growth hormone deficiency and acromegaly, metabolic disturbances stemming from the respective primary diseases may affect glucagon secretion.
Interleukin 8 in Behçet's Disease (1994)

Activated peripheral polymorphonuclear leukocytes (PMNs) and infiltration of PMNs into the lesions are characteristic findings of Behçet's disease (BD). A variety of cytokines, including interleukin 8 (IL-8), have been shown to activate PMNs. To investigate the role of IL-8 in the development of BD lesions, IL-8 production in vivo and in vitro was examined in 25 BD patients. IL-8 levels measured by ELISA in the non stimulated culture supernatants of peripheral mononuclear cells (MNCs) were higher in patients with active BD than in those with inactive BD or normal controls. Without LPS stimulation, IL-8 mRNA expression in incubated MNCs detected by Northern blot analysis was higher in active BD patients than in controls. Polarization assay confirmed the accelerated activity of PMN isolated from patients with active BD. However, these PMNs did not respond to IL-8 as strongly as to FMLP (an exogenous stimulator); a possible reason is that the PMNs of these patients are constantly exposed to IL-8 in vivo. Immunohistochemically, MNCs, endothelial cells and fibroblasts in BD lesions were positively stained by anti-IL-8 antibody. These data indicate that the production of IL-8 may be accelerated in inactive BD and that IL-8 may play an important role in the pathogenesis of BD.
Flexible fluoropolymer filled protective coatings (1991)

Metal oxide films such as SiO2 are known to provide an effective barrier to the transport of moisture as well as gaseous species through polymeric films. Such thin film coatings have a tendency to crack upon flexure of the polymeric substrate. Sputter co-deposition of SiO2 with 4 to 15 percent fluoropolymers was demonstrated to produce thin films with glass-like barrier properties that have significant increases in strain to failure over pure glass films which improves their tolerance to flexure on polymeric substrates. Deposition techniques capable of producing these films on polymeric substrates are suitable for durable food packaging and oxidation/corrosion protection applications.
Numerical simulation of contraction flow for viscoelastic fluids at high Weissenberg number by the streamline‐upwind finite element method (1993)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Yoshifumi Kuwano, Toshihisa Kajjwara, Kazumori Funatsu; Numerical simulation of contraction flow for viscoelastic fluids at high Weissenberg number by the streamline‐upwind finite element method. J. Rheol. 1 May 1993; 37 (3): 566. https://doi.org/10.1122/1.550431 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentThe Society of RheologyJournal of Rheology Search Advanced Search |Citation Search
A monoanionic pentadentate ligand platform for scandium–pnictogen multiple bonds (2021)

A new monoanionic pentadentate ligand is designed to accommodate Sc = E bonds (E = N, P). The imido complex is stable enough to isolate and characterize, and reacts rapidly with CO<sub>2</sub>. The phosphinidene, on the other hand, is highly reactive and induces C-C bond cleavage to yield a phosphido-pyridyl complex which also undergoes rapid reacton with CO<sub>2</sub>.
Dipotassium Hydrogen Phosphate-Catalyzed Synthesis of Dialkyl 2-(4-Fluoro-Phenoxy)-2-Butendioates From Stabilized Phosphorus Ylides in Solvent-Free Conditions (2007)

Protonation of the highly reactive 1:1 intermediates, produced in a reaction between triphenylphosphine and dialkyl acetylenedicarboxylates, by 4-fluorophenol leads to vinyltriphenylphosphonium salts, which undergo a Michael addition reaction with a conjugate base to produce dialkyl 2-(4-fluoro-phenoxy)-3-(triphenylphosphoranylidene)butanedioates. Dipotassium hydrogen phosphate powder was found to catalyze the conversion of dialkyl 2-(4-fluoro-phenoxy)-3-(triphenylphosphoranylidene)butanedioates to dialkyl 2-(4-fluoro-phenoxy)-2-butenedioates in solvent-free conditions under microwave (0.5 KW, 3 min) and thermal (90°C, 60 min) conditions.
Multi-access fading channels: delay-limited capacities (2002)

We consider the multi-access, white-noise, fading channel, and introduce a notion of delay-limited capacity, which is the maximum rate achievable with delay independent of how slow the fading is. We characterize the delay-limited capacity region and the associated optimal power allocation schemes. We show that successive decoding is optimal, and the optimal decoding order and power allocation can be found explicitly as a function of the fading states; this is a consequence of an underlying polymatroid structure that we exploit.
FDA approved drugs as potential Ebola treatments (2015)

<ns3:p> In the search for treatments for the Ebola Virus, multiple screens of FDA drugs have led to the identification of several with promising <ns3:italic>in vitro</ns3:italic> activity. These compounds were not originally developed as antivirals and some have been further tested in mouse <ns3:italic>in vivo</ns3:italic> models. We put forward the opinion that some of these drugs could be evaluated further and move into the clinic as they are already FDA approved and in many cases readily available. This may be important if there is a further outbreak in future and no other therapeutic is available. </ns3:p>
Susceptibility of various human tissues to transformation in vivo with human papillomavirus type 11 (1987)

Human papillomaviruses (HPVs) are associated with proliferative lesions in a variety of human epithelial types. In some cases, the associations are highly specific in that a certain papillomavirus type may infect only one human epithelial cell phenotype. In other cases, one papillomavirus apparently infects several tissue types and not others. Further, HPV replication capacity varies considerably in different epithelia. Due to the lack of a suitable method, it has not been possible, until now, to define the role of the host cell phenotype in determining the outcome of infection with an HPV. We recently developed a system in which human epithelium was exposed to HPV-II and transplanted to athymic mice. Cervix and skin grafts developed into typical condylomata. We now test the hypothesis that the outcome of infection of diverse epithelial types with a single human papillomavirus is largely determined by the phenotype of the original epithelial cell. For example, skin obtained from a number of disparate sites from a single patient varied dramatically in its capacity for morphological transformation with HPV-II. Skin from penis was highly susceptible, but skin from abdomen did not transform. Vocal cord from 3 children and 2 adults responded to HPV-II infection by producing typical laryngeal papillomata. A variety of tissues were obtained from II donor infants and infected with HPV-II. Foreskin and cervical tissues of these children were transformed at a frequency of 100%. Vocal cord was transformed at an incidence of 88% and urethra at 73%. Only 37% of esophagus samples were transformed and both abdominal skin and urinary bladder from the same infants were totally resistant to morphological transformation. In a separate study, ureteral tissues from a child and an adult were completely resistant to HPV-II infection. Papillomavirus replication was readily detected as capsid antigen in foreskin, cervix, and urethra, but was poorly expressed in morphologically-transformed esophagi and vocal cords. In the last two tissues HPV-II DNA and RNA were demonstrated in cells by in situ hybridization techniques. We conclude that the epithelial cell phenotype is a major determinant of HPV-II infection, controlling both morphological transformation and viral replication.