gebhart/patrepeval huggingface dataset:
Abstract 21036: Subablative Therapeutic Ultrasound Reduces Mitral and Tricuspid Annular Dimension: Preclinical Evaluation of the ReCor Device (2010)

Background: We hypothesized that Therapeutic Ultrasound(TU) from the ReCor device could result in a reduction in mitral annular(MA) and tricuspid annular(TA) dimension with potential application in...
Real-Time Action Recognition With Deeply Transferred Motion Vector CNNs (2018)

The two-stream CNNs prove very successful for video based action recognition. However the classical two-stream CNNs are time costly, mainly due to the bottleneck of calculating optical flows. In this paper, we propose a two-stream based real-time action recognition approach by using motion vector to replace optical flow. Motion vectors are encoded in video stream and can be extracted directly without extra calculation. However directly training CNN with motion vectors degrades accuracy severely due to the noise and the lack of fine details in motion vectors. In order to relieve this problem, we propose four training strategies which leverage the knowledge learned from optical flow CNN to enhance the accuracy of motion vector CNN. Our insight is that motion vector and optical flow share inherent similar structures which allows us to transfer knowledge from one domain to another. To fully utilize the knowledge learned in optical flow domain, we develop deeply transferred motion vector CNN. Experimental results on various datasets show the effectiveness of our training strategies. Our approach is significantly faster than optical flow based approaches and achieves processing speed of 390.7 frames per second, surpassing real-time requirement. We release our model and code to facilitate further research.
A Simple and Efficient Surgical Technique for Subungual Exostosis (2001)

Subungual exostosis is a benign osteochondral tumor usually involving the distal phalanx of the great toe. The lesion most frequently occurs in the second and third decades of life and is rare before the age of 10 years. There are few reports of its occurrence in children, and most of them advocate partial or complete nail excision to treat this lesion successfully. We report our experience with six children and adolescents using a simple surgical technique that involves approaching the exostosis under the nail to preserve nail coverage. Rapid recovery and excellent cosmetic appearance were achieved immediately after the operation.
Sequential and coordinated action of phytochromes A and B during Arabidopsis stem growth revealed by kinetic analysis (1999)

Photoreceptor proteins of the phytochrome family mediate light-induced inhibition of stem (hypocotyl) elongation during the development of photoautotrophy in seedlings. Analyses of overt mutant phenotypes have established the importance of phytochromes A and B (phyA and phyB) in this developmental process, but kinetic information that would augment emerging molecular models of phytochrome signal transduction is absent. We have addressed this deficiency by genetically dissecting phytochrome-response kinetics, after having solved the technical issues that previously limited growth studies of small Arabidopsis seedlings. We show here, with resolution on the order of minutes, that phyA initiated hypocotyl growth inhibition upon the onset of continuous red light. This primary contribution of phyA began to decrease after 3 hr of irradiation, the same time at which immunochemically detectable phyA disappeared and an exclusively phyB-dependent phase of inhibition began. The sequential and coordinated actions of phyA and phyB in red light were not observed in far-red light, which inhibited growth persistently through an exclusively phyA-mediated pathway.
Simple and Efficient Reduction of Aromatic Nitro Compounds Using Recyclable Polymer‐Supported Formate and Magnesium. (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
Ginkgolide B Regulates CDDP Chemoresistance in Oral Cancer via the Platelet-Activating Factor Receptor Pathway (2021)

The platelet-activating factor receptor (PAFR) is a key molecule that participates in intracellular signaling pathways, including regulating the activation of kinases. It is involved in cancer progression, but the detailed mechanism of its chemosensitivity is unknown. The purpose of the current study was to elucidate the mechanism regulating cisplatin (CDDP) sensitivity through PAFR functions in oral squamous cell carcinoma (OSCC). We first analyzed the correlation between PAFR expression and CDDP sensitivity in seven OSCC-derived cell lines based upon cell viability assays. Among them, we isolated 2 CDDP-resistant cell lines (Ca9-22 and Ho-1-N-1). In addition to conducting PAFR-knockdown (si<i>PAFR</i>) experiments, we found that ginkgolide B (GB), a specific inhibitor of PAFR, enhanced both CDDP chemosusceptibility and apoptosis. We next evaluated the downstream signaling pathway of PAFR in si<i>PAFR</i>-treated cells and GB-treated cells after CDDP treatment. In both cases, we observed decreased phosphorylation of ERK and Akt and increased expression of cleaved caspase-3. These results suggest that PAFR is a therapeutic target for modulating CDDP sensitivity in OSCC cells. Thus, GB may be a novel drug that could enhance combination chemotherapy with CDDP for OSCC patients.
[Advantages of intravascular ultrasound--preliminary experience in patients with peripheral and renal vascular disease]. (1993)

Intravascular ultrasound (IVUS) is a new method in which endovascular images are obtained from a catheter inserted into an artery. We uses IVUS during PTA of iliac and renal artery, and examined its effectiveness. Three layers are well defined in normal arterial wall. Calcified deposits are recognized as a combination of strong echo and acoustic shadow. The absolute cross sectional area of patent lumen and atherosclerotic plaque can be calculated. IVUS is very effective for the assessment of PTA. The increased caliber of arteries following PTA is caused by the over stretching of the media rather than the compression of atheroma.
[Modern cosmetic agents and evidence of their function]. (1990)

Fluorometers modified by quartz light conductors allow the recording of the skin-intrinsic fluorescence. Signals assigned to the aromatic amino acids permit a prognosis concerning the sensitivity of untreated skin to light and the sunscreen factor to be expected after the application of UV filters. We discuss the microdistribution and skin penetration of UV filters and describe the utilization of the image analysis technique both for the count and size determination of fluorescent sebaceous glands and for the quantification of the effects of antiperspirants. Based both on the selective increase of efficacy of deodorant soaps, analytically controlled, and on the differences of the deodorizing effects found in various test groups, we discuss the possibilities of improving deodorants.
Analytically Useful Spectra Excited in an Atmospheric Pressure Active Nitrogen Afterglow (1984)

An atmospheric pressure active nitrogen (APAN) discharge has been utilized for producing characteristic molecular emissions from nonmetallic species introduced into the afterglow region of the discharge. The addition of inorganic S-, P-, B-, CI-, and Br-containing compounds into the afterglow has resulted in the formation of excited S 2 , PN, BO, NCI, and NBr species, respectively. Intense molecular Br 2 emission and I 2 emission, as well as atomic I emission, have also been observed. Preliminary analytical utilization of the molecular or atomic emissions observed revealed that the APAN afterglow may serve as a potentially useful detector for the aforementioned elements.
The Future of Organic Chemistry–an Essay (2012)

This chapter contains sections titled: Introduction The Field of Organic Chemistry Will Broaden Conclusion
INDIRECT DETECTION METHODS FOR CAPILLARY SEPARATIONS (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTINDIRECT DETECTION METHODS FOR CAPILLARY SEPARATIONSEdward S. Yeung and Werner G. KuhrCite this: Anal. Chem. 1991, 63, 5, 275A–282APublication Date (Print):March 1, 1991Publication History Published online30 May 2012Published inissue 1 March 1991https://pubs.acs.org/doi/10.1021/ac00005a721https://doi.org/10.1021/ac00005a721research-articleACS PublicationsRequest reuse permissionsArticle Views147Altmetric-Citations96LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Techniques for estimating blood pressure variation using video images (2015)

It is important to know about a sudden blood pressure change that occurs in everyday life and may pose a danger to human health. However, monitoring the blood pressure variation in daily life is difficult because a bulky and expensive sensor is needed to measure the blood pressure continuously. In this study, a new non-contact method is proposed to estimate the blood pressure variation using video images. In this method, the pulse propagation time difference or instantaneous phase difference is calculated between two pulse waves obtained from different parts of a subject's body captured by a video camera. The forehead, left cheek, and right hand are selected as regions to obtain pulse waves. Both the pulse propagation time difference and instantaneous phase difference were calculated from the video images of 20 healthy subjects performing the Valsalva maneuver. These indices are considered to have a negative correlation with the blood pressure variation because they approximate the pulse transit time obtained from a photoplethysmograph. However, the experimental results showed that the correlation coefficients between the blood pressure and the proposed indices were approximately 0.6 for the pulse wave obtained from the right hand. This result is considered to be due to the difference in the transmission depth into the skin between the green and infrared light used as light sources for the video image and conventional photoplethysmogram, respectively. In addition, the difference in the innervation of the face and hand may be related to the results.
A prediction-based link availability estimation for routing metrics in MANETs (2005)

A Mobile Ad hoc Network (MANET) is a collection of wireless mobile terminals that are able to dynamically form a temporary network without any aid from fixed infrastructure or centralized administration. One critical issue for routing in MANETs is how to select reliable paths that can last as long as possible since terminal mobility may cause radio links to be broken frequently. To solve this problem, a criterion that can judge path reliability is needed. The reliability of a path depends on the number of links and the reliability of each link constituting the path. Many routing metrics in terms of number of links have been proposed, such as the shortest path routing. However, how to measure link availability or reliability in order to find more reliable paths has not been addressed adequately in the literature. (By a link being available, we mean that the radio quality of the link satisfies the minimum requirement for successful communication. Link availability is used to measure probability or degree that a link is available. The terms availability and reliability are used interchangeable in this paper.) This paper first introduces a prediction-based link availability estimation to quantify the link reliability. This quantity makes use of some instantly available information and also considers the dynamic nature of link status in order to properly reflect the link reliability. Then, this quantity has been further used to develop routing metrics for path selection in terms of path reliability to improve routing performances. The proposed schemes have been investigated through computer simulation.
A 64 min single-chip voice recorder/player using embedded 4 bit/cell flash memory (2002)

A system-on-chip prototype implements a full integration of a 64-minute digital voice recorder/player embedding a 4 bit/cell multilevel digital flash memory. A speech coder/decoder (8 to 40 kbps), an MCU and an 8 Mcell/32 Mb multilevel flash memory with fully digital on-chip BIST solution are integrated in a 0.5 /spl mu/m embedded flash technology. The system features a modular architecture allowing full reuse and mix-and-match of its IP building blocks. The chip counts 13M transistors at 225 mm/sup 2/ area.
Comparison of plasma clearance of exogenous creatinine, exo-iohexol, and endo-iohexol over a range of glomerular filtration rates expected in cats (2009)

The study investigated plasma clearance of exogenous creatinine (PECCT), exo-iohexol (PexICT) and endo-iohexol (PenICT) in six healthy cats, four cats with chronic kidney disease (CKD) and six hyperthyroid (HT) cats to assess potential differences in glomerular filtration rate (GFR) measurement over a wide range of GFR values. The PECCT, PexICT and PenICT were performed in a combined protocol. There was a significant difference between PexICT and PenICT and PECCT in healthy cats. Differences between clearance techniques are suggested to be correlated to range in GFRs and should be taken into account when GFR is measured.
Shaping and Slotting High-Q Spherical Resonators for Suppression of Higher Order Modes (2019)

This paper proposes two methods to improve the spurious-free stopband range for high-quality-factor spherical resonators and a new family of shaped spherical resonators are presented. Geometrical shaping of the proposed resonators is realized by symmetrically squeezing a spherical cavity and further opening a rectangular slot in each squeezed area. The higher order modes of the resonator are first tuned spectrally farther away from the dominant mode by the squeezing, and then are suppressed by the slotting. X-band resonator prototypes are designed, and 3-D printed by using a metallic selective laser melting technique. Quality factors of the fabricated resonators are further improved by vibration grinding process. The experiment validates effective suppression of the first higher order mode and indicates potential applications of the proposed resonators in bandpass filters to extend the spurious-free stopband bandwidths.
Burkholderia graminis sp. nov., a rhizospheric Burkholderia species, and reassessment of [Pseudomonas] phenazinium, [Pseudomonas] pyrrocinia and [Pseudomonas] glathei as Burkholderia (1998)

In a survey of soil and wheat or maize rhizoplane bacteria isolated using a medium containing azelaic acid and tryptamine as sole carbon and nitrogen sources, respectively, a large proportion of Burkholderia-like bacteria were found. Among them, a homogeneous group of strains was identifiable based on phenotypic properties, fatty acid composition, DNA-DNA hybridizations and 16S rDNA sequences. According to molecular data, this group belongs to the genus Burkholderia but its weak similarity to previously described species suggests that it belongs to a novel species. Closest 16S rDNA phylogenetic neighbours of this species are Burkholderia caryophylli and two previously named Pseudomonas species which clearly appear to be part of the Burkholderia genus and were thus named Burkholderia glathei comb. nov. and Burkholderia phenazinium comb. nov. Strains of the new species are oxidase- and catalase-positive, produce indole and gelatinase, and use L-xylose, lactose, rhamnose, trehalose, D-lyxose, L-arabitol, xylitol and D-raffinose as sole carbon source. This novel taxon is named Burkholderia graminis. In the course of this study, [Pseudomonas] pyrrocinia also proved to be a member of the Burkholderia genus.
Unveiling the molecular crosstalk in a human induced pluripotent stem cell‐derived cardiac model (2019)

In vitro cell-based models that better mimic the human heart tissue are of utmost importance for drug development and cardiotoxicity testing but also as tools to understand mechanisms related with heart disease at cellular and molecular level. Besides, the implementation of analytical tools that allow the depiction and comprehensive understanding of the molecular mechanisms of the crosstalk between the different cell types is also relevant. In this work, we implemented a human cardiac tissue-like in vitro model, derived from human-induced pluripotent stem cell (hiPSC), and evaluated the relevance of the cell-cell communication between the two of the most representative cell populations of the human heart: cardiomyocytes (hiPSC-CM) and endothelial cells (hiPSC-EC). We observed that heterotypic cell communication promotes: (a) structural maturation of hiPSC-CM and (b) deposition of several extracellular matrix components (such as collagens and fibronectin). Overall, the toolbox of analytical techniques used in our study not only enabled us to validate previous reports from the literature on the importance of the presence of hiPSC-EC on hiPSC-CM maturation, but also bring new insights on the molecular mechanisms involved in the communication between these two cell types when cocultured in vitro.
Astrocytic theory of working memory (2014)

Figure A Simulated firing activity of a cortical neuron before, during and after the presentation of a stimulatory cue (purple bar). B The same cue induces persistent firing activity in presence of astrocyte-mediated synaptic facilitation for more than 10 seconds (red shade). C Astrocyte-mediated facilitation results in bistability of synaptic release. D Synaptic release enhanced by the astrocyte may outlast the stimulatory cue as long as the astrocyte is kept active by the very synaptic stimuli impinging on the astrocyte. E The resulting neuronal firing statistics is more irregular in presence of the astrocyte, as marked by (F) a coefficient of variation (CV) larger than 1 after presentation of the cue (purple shade).
Isolation and sequence of cDNA encoding a cytochrome P-450 from an insecticide-resistant strain of the house fly, Musca domestica. (1989)

A cDNA expression library from phenobarbital-treated house fly (Musca domestica) was screened with rabbit antisera directed against partially purified house fly cytochrome P-450. Two overlapping clones with insert lengths of 1.3 and 1.5 kilobases were isolated. The sequence of a 1629-base-pair (bp) cDNA was obtained, with an open reading frame (nucleotides 81-1610) encoding a P-450 protein of 509 residues (Mr = 58,738). The insect P-450 protein contains a hydrophobic NH2 terminus and a 22-residue cysteine-containing fragment near the COOH terminus that is known to bind the heme; both of these features have been found in the more than five dozen vertebrate P-450 proteins of which the sequences are presently known. Interestingly, the termination codon UAA may be contained in a putative polyadenylylation signal (AAUAAA) of the mRNA. This P-450 protein exhibits the most similarity (27% amino acid positional identity) with mammalian proteins of the P450III family but qualifies as a member of another family, which we propose to designate the P450VI gene family. This cDNA and deduced protein sequence should provide important information in the study of evolution of the P-450 gene superfamily, as well as provide an important probe for studying the regulation of insect P-450 and understanding the molecular genetics of insecticide resistance.
Long-term results after nailing in situ of slipped upper femoral epiphysis (1998)

We reviewed the radiological and clinical long-term results after the nailing in situ of slipped upper femoral epiphysis in 59 hips in 43 patients. The displacement of the epiphysis had been measured as the ‘slipping angle’ before operation and related to the results at follow-up at a mean of 30.9 years (27 to 34). The mean age at follow-up was 44.2 years (39 to 50). Radiographic re-examination of 41 hips with slipping angles of ≤30° at the time of operation showed that eight (20%) had developed mild osteoarthritis and one had severe changes. For 18 hips with slipping angles ranging from 31 to 50° at surgery six (33%) had mild osteoarthritis and three had severe changes. The differences did not quite achieve statistical significance (p = 0.09). Clinical re-examination of the 41 hips with slipping angles of ≤30° showed fair or poor results (Harris hip score &lt; 90) in three (7%). In the 18 hips with slipping of 31 to 50°, four had fair or poor results (22%) (p= 0.13). We conclude that nailing in situ for slipping of ≤30°, using one thin nail, can give excellent long-term results. At present we recommend that hips with slips ranging from 31 to 50° should also be nailed in situ, but further long-term studies are required, especially on the choice between nailing in situ and corrective osteotomy for slips in excess of 50°.
Evaluating the Impact of 3-Dimensional Laparoscopic Imaging on the Surgical Team Using Subjective Multidimensional Assessment Tools (2019)

Gabrielli, Mauricio MD, MSc; Jung, James J. MD; Saun, Tomas MD; Grantcharov, Teodor MD, PhD, FACS Author Information
Candidate Antigens for Q Fever Serodiagnosis Revealed by Immunoscreening of a Coxiella burnetii Protein Microarray (2008)

Q fever is a widespread zoonosis caused by Coxiella burnetii. Diagnosis of Q fever is usually based on serological testing of patient serum. The diagnostic antigen of test kits is formalin-fixed phase I and phase II organisms of the Nine Mile reference strain. Deficiencies of this antigen include (i) potential for cross-reactivity with other pathogens; (ii) an inability to distinguish between C. burnetii strains; and (iii) a need to propagate and purify C. burnetii, a difficult and potentially hazardous process. Consequently, there is a need for sensitive and specific serodiagnostic tests utilizing defined antigens, such as recombinant C. burnetii protein(s). Here we describe the use of a C. burnetii protein microarray to comprehensively identify immunodominant antigens recognized by antibody in the context of human C. burnetii infection or vaccination. Transcriptionally active PCR products corresponding to 1,988 C. burnetii open reading frames (ORFs) were generated. Full-length proteins were successfully synthesized from 75% of the ORFs by using an Escherichia coli-based in vitro transcription and translation system (IVTT). Nitrocellulose microarrays were spotted with crude IVTT lysates and probed with sera from acute Q fever patients and individuals vaccinated with Q-Vax. Immune sera strongly reacted with approximately 50 C. burnetii proteins, including previously identified immunogens, an ankyrin repeat-domain containing protein, and multiple hypothetical proteins. Recombinant protein corresponding to selected array-reactive antigens was generated, and the immunoreactivity was confirmed by enzyme-linked immunosorbent assay. This sensitive and high-throughput method for identifying immunoreactive C. burnetii proteins will aid in the development of Q fever serodiagnostic tests based on recombinant antigen.