gebhart/patrepeval huggingface dataset:
Medical Prescription Recognition using Machine Learning (2021)

Admittedly, because of how busy doctors are nowadays, they tend to scribble unreadable prescribed medicines which leads to the problem of misinterpreting medicine names. Patients are sometimes curious to know information about their prescribed medicines before purchasing them. Recently, developers have been searching for a method to address this problem efficiently but, no technique leads to full recognition of medicine names due to the bad handwriting of doctors and its variety so that leads us to machine learning where the system will learn various types of handwritings for the same medicine to be able to recognize new handwritings. This paper proposed a system that presents a solution for both the pharmacist and the patient through a mobile application that recognizes handwritten medicine names and returns a readable digital text of the medicine and its dose. The System identifies the medicines' names and the doses for the collected data set with some, pre-processing techniques like image subtraction, noise reduction, and image resizing. After that, the pre-processed images will undergo some processing as it will be classified and feature extracted through Convolutional Neural Network and finally Optical Character Recognition technique applied on the medicines with low accuracy in the post-processing phase to identify their names by comparing the result with the dataset containing all the medicines. This will help in diminishing the instances of distortion of medication names assisting pharmacists in limiting their doubts. The proposed system tested on different real cases, and accuracy has reached 70% using (CNN) model.
Proposal for a privacy policy manager as architecture for a new privacy-enhancing platform (2017)

Refinement of the legal framework that balancesthe protection and usage of personal data in online and offline services has been discussed globally. On the other hand, because of information asymmetry between users and service providers and bounded rationality of users, the existing notice-and-consent mechanism (Solove’s privacy self-management model) has proven inadequate in itseffectiveness. This research contributes to solvingthe abovementioned issues usinga complementary technical system(named Privacy Policy Manager). The Privacy Policy Manager creates users’privacy policies based on theirpreferences and supports them incontrollingdata disclosure and data usage in accordance with thesepolicies.
Keeping it simple (2020)

With its focus on simplicity, nature and the beauty to be found in the old and imperfect, how might the wisdom of wabi sabi inform the environment we create for children in our setting?
Unclassified (2009)

The wideband global SATCOM (WGS) system is currently operational in the Pacific Ocean using WGS1 (175E). GBS traffic is supported in that theater today using the digital video broadcast by satellite (DVB-S) and operates using terminals originally designed for operation using the UHF follow-on satellite (UFO8). These terminals can now operate over WGS1 and UFO8. GBS is planned to migrate to the joint IP modem (JIPM) in 2010. The JIPM will use the second generation DVB-S2 which represents a quantum leap in capability over DVB-S in terms of its power and bandwidth efficiency. Further, the JIPM allows hub-spoke operation between a control center at a Teleport and the remote terminals equipped with a remote modem. This paper will address the data rate performance of GBS terminals using the current DVB-S and the JIPM DVB-S2 over WGS1 (175E), WGS2 (60E) and WGS3 (12W). First, a reference link is defined based on the next generation receive terminal (NGRT). Next, data rates will be determined for the reference link based on measured WGS1 data. Finally, global availability maps will be determined for the reference link when operating over WGS1, WGS2, and WGS3 using WGS Ka-band beams.
NEO-BULK SHIP SYSTEM CONCEPT STUDIES (1972)

The neo-bulk concept design studies were organized into three tasks: (1) a computer design study of state-of-the-art neo-bulk shipping characteristics and costs for a broad range of parameters; (2) a limited investigation of the economics of selected neo-bulk ship concepts in operation at the time of the study; and (3) a study of developmental system concepts, such as tug-barge systems and barge carriers, in which the propulsion plant and crew are maintained at a high utilization level compared with the cargo-carrying portion of the system. The study concludes with a proposal for specialized products carriers to be considered for neo-bulk service.
Evidence that nitric oxide mechanisms regulate small intestinal motility in humans (1999)

These observations suggest that NO mechanisms play a role in the regulation of fasting small intestinal motor activity in humans.
Long-wavelength waveguide multiple-quantum-well (MQW) optical modulator with 30:1 on/off ratio (1986)

Large on/off ratio optical modulation of long-wavelength light propagating along the plane of InGaAs/InAlAs multiple-quantum-well (MQW) structures grown by molecular beam epitaxy (MBE) is obtained for the first time. These waveguide MQW optical modulators have a modulation on/off ratio of 30:1 (15 dB) at a driving voltage as low as 9 V, and a capacitance-limited pulse response of 280 ps (FWHM). This measurement is the first step in achieving faster and higher extinction ratio devices.
Immunologic Evaluation of Patients with Cefotetan-Induced Anaphylaxis (2015)

Cefotetan is a commonly prescribed second-generation cephalosporin that acts against a wide range of bacteria. However, cefotetan-induced hypersensitivity has rarely been reported. We report 2 cases of cefotetan-induced anaphylaxis with immunologic evaluation. The first case was a 70-year-old asthmatic woman who had dyspnea and hypotension during administration of cefotetan, in which high serum-specific IgE to cefotetan-human serum albumin (HSA) conjugate was detected by enzyme-linked immunosorbent assay. The second case was a 63-year-old asthmatic woman who complained of chest tightness and dyspnea during cefotetan infusion, in which high serum-specific IgG1 and IgG4 with no serum specific IgE to cefotetan-HSA conjugate was detected. The basophil activation test using basophils from the patient showed a significant up-regulation of CD63 with the addition of anti-IgG4 antibody compared with that in non-atopic healthy controls. In conclusion, cefotetan can induce anaphylaxis, which may involve both IgE- and IgG4-mediated responses in the pathogenic mechanism.
A simplified Bethesda system for reporting thyroid cytopathology using only four categories improves intra‐ and inter‐observer diagnostic agreement and provides non‐overlapping estimates of malignancy risks (2011)

Our previous study utilizing the 2008 NCI six-category system (also known as The Bethesda System) for reporting thyroid fine-needle aspirations (FNA) identified considerable overlap in diagnosis and in assigned malignancy risk estimates for the "follicular lesion of undetermined significance (FLUS)" and "follicular neoplasm (FN)" categories and for the "suspicious for malignancy (Susp)" and "malignant" categories. We proposed a simplified Bethesda System for reporting thyroid FNAs that provided four non-overlapping, statistically significant, and more clinically relevant diagnostic categories: unsatisfactory, benign, FLUS/FN, and Susp/malignant. In the current study, six cytopathologists participated in a blinded retrospective review of 60 thyroid FNAs and kappa statistics were utilized to compare the intra- and inter-observer diagnostic agreements obtained using the six-category and the simplified four-category schemes. Surgical follow-up was used to determine which scheme provided more discrete malignancy risk estimates. Use of the simplified four-category scheme significantly improved intra- and inter-observer diagnostic agreement levels, significantly increased the sensitivity of FNA for a diagnosis of carcinoma in the subsequently resected thyroid glands, and provided non-overlapping malignancy risk estimates for each diagnostic category.
MS2Analyzer: A Software for Small Molecule Substructure Annotations from Accurate Tandem Mass Spectra (2014)

Systematic analysis and interpretation of the large number of tandem mass spectra (MS/MS) obtained in metabolomics experiments is a bottleneck in discovery-driven research. MS/MS mass spectral libraries are small compared to all known small molecule structures and are often not freely available. MS2Analyzer was therefore developed to enable user-defined searches of thousands of spectra for mass spectral features such as neutral losses, m/z differences, and product and precursor ions from MS/MS spectra in MSP/MGF files. The software is freely available at http://fiehnlab.ucdavis.edu/projects/MS2Analyzer/ . As the reference query set, 147 literature-reported neutral losses and their corresponding substructures were collected. This set was tested for accuracy of linking neutral loss analysis to substructure annotations using 19 329 accurate mass tandem mass spectra of structurally known compounds from the NIST11 MS/MS library. Validation studies showed that 92.1 ± 6.4% of 13 typical neutral losses such as acetylations, cysteine conjugates, or glycosylations are correct annotating the associated substructures, while the absence of mass spectra features does not necessarily imply the absence of such substructures. Use of this tool has been successfully demonstrated for complex lipids in microalgae.
Treating Angina Pectoris By Acupuncture Therapy (2013)

Acupuncture therapy on PC 6 (Neiguan) has a therapeutic effect on cardiac and chest ailments including angina pectoris. Additional beneficial acupuncture points are PC 4 (Ximen), HT 7 (Shenmen point), PC 7 (Daling point), PC 5 (Jianshi point), PC 3 (Quze point), CV 17 (Danzhong point), CV 6 (Qihai point), BL 15 (Xinshu point), L 20 (Pishu point), BL 17 (Geshu point), BL23 (Shenshu point), B18 (Ganshu point), HT 5 (Tongli point), and ST36 (Zusanli point). Acupuncture not only quickly relieve the symptoms of acute angina pectoris, but also improve nitroglycerine's therapeutic effects. Therefore, it is an efficient simple therapeutic method used for emergency and for regular angina treatment. Review of studies on acupuncture therapy has shown effectiveness were between 80% to 96.2% that are almost as effective as conventional drug regimen. When compared with conventional medical treatment, the acupuncture therapy shows the obvious advantage of lacking, adverse side effects commonly associated with the Western anti-anginal drugs such as 1) Nitroglycerine (headache-63% with nitroglycerine patch and 50% with spray; syncope-4%; and dizziness-8% with patch; hypotension-4% with patch; and increased angina 2% with patch). 2) Isosorbide mononitrate (dizziness-3 to 5%; nausea/vomiting-2 to 4% and other reactions including hypotension, and syncope even with small doses). 3) Propranolol (bradycardia, chest pain, hypotension, worsening of AV conduction disturbance, Raynaud's syndrome, mental depression, hyperglycemia, etc.). Many conventional anti-anginal medications cause inter-drug reactions with other medications the patients taking for other diseases. Whereas, acupuncture therapy does not pose such an interference with patient's medications. Nevertheless, surgery is still the treatment of choice when acupuncture or conventional drug therapy fails. Combination of conventional drug therapy and acupuncture would considerably decrease the frequency and the required dosage of drug taking, thereby decreasing the unpleasant side effects of the drug therapy.
Beetle-Swarm Evolution Competitive Algorithm for Bridge Sensor Optimal Placement in SHM (2019)

In structural heath monitoring (SHM), for the sake of optimizing the bridge sensor placement, a beetle-swarm evolution competitive algorithm is proposed with the group evolutionary competition mechanism introducing into beetle antennae search optimization (BAS). This paper uses high-dimensional dynamic coverage coding to initialize the beetle's location as binary codes, which avoids that the original BAS can only solve the continuous optimization problem, and ensures the dispersion of effective information in individuals, so that the coding rules are consistent with the actual coverage density for bridge sensors. In the process of evolutionary, horizontal mutation, crossover, phagocytosis and elimination among individuals are added to improve the diversity of individual evolution, which may avoid the algorithm falling into local optimum, and make the excellent individuals tend to be better. Lastly, the example analysis of Ha-Qi bridge shows that beetle-swarm evolution competitive algorithm has fast convergence speed and global optimization ability, and it is suitable for solving the sensor placement optimization for large bridge.
Surface Precipitation of Highly Porous Hydrotalcite-like Film on Al from a Zinc Aqueous Solution (2006)

A hydrotalcite-like film has been successfully deposited on an Al-bearing glass substrate based on an interface reaction between an Al layer and a zinc aqueous solution. The film selectively grew on the Al surface but not on the glass surface. The film on Al was composed of layered nanosheets of a hydrotalcite-like compound containing Al and Zn. Comparably, deposits on the plastic surface and precipitates in solution were wurzite-type ZnO with various morphologies depending upon the preparation conditions. At low supersaturation degrees, single crystals and superstructures of Zn-Al hydrotalcite were also obtained. This porous hydrotalcite film has a potential application as catalyst supports, environmental materials, or matrixes for hydrotalcite-based nanocomposite films. Using Al as a reaction interface makes it easy to coat porous hydrotalcites on a series of matrix materials varying in shapes and properties, which is important for achieving practical applications. In addition, the method developed should be widely applicable to other systems for the preparation of porous or oriented hydrotalcite-like thin films by an appropriate combination of divalent/trivalent solution-substrate systems.
0717 Peer-intervention Can Reduce Health Disparities In Patients With Obstructive Sleep Apnea (2020)

Abstract Introduction In patients with obstructive sleep apnea (OSA), adherence to continuous positive airway pressure (CPAP) therapy is a major problem. Moreover, up to 20% of patients with suspected OSA who are referred to sleep study testing do not adhere to such diagnostic work-up. Although, peer-driven intervention with an interactive voice response system (PDI-IVR) can improve CPAP adherence, whether such an intervention can improve adherence to sleep study testing is unknown. Also, there remain health disparities with greater levels of CPAP nonadherence disproportionately affecting individuals of lower socioeconomic status. We aimed to determine whether PDI-IVR can improve adherence to sleep study testing and CPAP adherence in a lower income population. Methods We performed a prospective, randomized, parallel group, controlled trial wherein patients with suspected OSA were randomly assigned to receive PDI-IVR or provided with educational information regarding OSA and CPAP therapy (attention-control group) while both groups received usual care. The PDI-IVR interactions aimed at promoting adherence to sleep study testing and in patients diagnosed with OSA the peer-intervention was focused on improving CPAP adherence. In the PDI-IVR group, trained peers (peer-buddies) with OSA were paired with randomized patients over a 6-month period combined with an ability to meet in-person, email, text message, or phone an inter-disciplinary team of providers. Results In this pilot study, there were 63 patients (48.4 ± 12.5 years; 30 men) who were randomized to intervention (n=31) and attention-control (n=32) arms. There were 36 peer-buddies who mentored the patients in the intervention group. Intention to treat analysis revealed that failure to undergo sleep study testing was 15.6% of patients in the attention-control arm and 9.7% in the PDI-IVR arm (P=0.7). Per protocol analysis revealed that failure to undergo sleep study testing was 18.4% of patients in the attention-control arm and 4% in the PDI-IVR arm (P=0.13). At 6 months, CPAP adherence was greater in PDI-IVR arm (290 ± 45 min [SE]) than attention-control arm (181 ± 43 min; P=0.01). Conclusion In a lower income population, PDI-IVR improved CPAP adherence with a tendency for better adherence to sleep-study testing. Peer-intervention can reduce sleep health disparities. Support HL138377
Structural Features of the Maize sus1 Gene and Protein (1994)

Genomic clones, cDNA clones, and protein of the maize (Zea mays L.) Suc synthase1 (sus1) gene were isolated and sequenced. Termini (5' and 3') of the transcribed unit were identified. The SUS1 protein was purified from tissue culture cells as a phosphorylated protein. The overall structure of sus1 is virtually identical with that of the paralogous gene, shrunken1 (sh1); however, the last intron of sh1 is missing in sus1. This intron bears much sequence similarity with the adjacent exon, suggesting that the intron arose from an internal duplication. Although the placement of the other 14 introns is identical in both genes, the introns exhibit markedly greater differences in size and sequence relative to that shown by the exons. An explanation for the differential rate of divergence of exons and introns is selection pressure for gene function. Additionally, comparisons of coding regions of plant sucrose synthases show that sh1-like and sus1-like genes can be found in all monocots so far analyzed. These latter observations point to an important role played by both genes in this group of plants.
Thermal Cycling Absorption Process—A New Way to Separate Hydrogen Isotopes (2015)

The thermal cycling absorption process (TCAP) is a semi-continuous chromatographic process for hydrogen isotope separation developed at the Savannah River Technology Center (SRTC) of the Savannah River Site (SRS) to support the tritium production and recycling operations for the national defense program. Hydrogen has three isotopes—protium, deuterium, and tritium. Among these, protium is known as normal hydrogen. Deuterium and tritium are heavier isotopes and are used in weapon systems. Deuterium and tritium fuse to form helium plus a free neutron, then releasing huge amounts of energy (1.7 trillion joules per mole). This is the source of energy for boost weapons. Fusion also serves another vital national interest—energy security. The prob-lem is that the separation process required to supply tritium is costly, cumbersome, and ineffi-cient. The TCAP method is compact, safer, and more efficient and an important technology for supporting the weapons program as well as for future fusion reactor fuel processing.
An empirical investigation of fault types in space mission system software (2010)

As space mission software becomes more complex, the ability to effectively deal with faults is increasingly important. The strategies that can be employed for fighting a software bug depend on its fault type. Bohrbugs are easily isolated and removed during software testing. Mandelbugs appear to behave chaotically. While it is more difficult to detect these faults during testing, it may not be necessary to correct them; a simple retry after a failure occurrence may work. Aging-related bugs, a sub-class of Mandelbugs, can cause an increasing failure rate. For these faults, proactive techniques may prevent future failures. In this paper, we analyze the faults discovered in the on-board software for 18 JPL/NASA space missions. We present the proportions of the various fault types and study how they have evolved over time. Moreover, we examine whether or not the fault type and attributes such as the failure effect are independent.
Developmental Expression of Src-Related Tyrosine Kinases in the Mouse Testis (2010)

An increase in protein tyrosine phosphorylation occurs during sperm capacitation in numerous species. The involvement of Src-related tyrosine kinases in this phenomenon has been demonstrated using different inhibitors specifically targeting this family of enzymes. In mammals, this group of nonreceptor tyrosine kinases is made up of 8 members with similar SRC homology domain 3 (SH3) and SH2 domains. Although some members of this group of enzymes can compensate for one another, showing some redundancy, each is unique and may perform specific functions during male germ cell development. To further characterize the importance of Src-related tyrosine kinases in the events leading to proper sperm formation, and because no inhibitor affecting a single gene product exists, expression of Src, Yes1, Fyn, Lyn, Lck, Hck, Blk, and Fgr was assessed by real-time polymerase chain reaction in developing mouse testes and in enriched populations of mouse spermatogenic cells, revealing distinct expression profiles for each kinase during testis development and in isolated male germ cells. Immunolocalization of SRC, LYN, and HCK in adult mouse testes as well as in mature spermatozoa further confirmed differential localization of these kinases during spermatogenesis. Although mRNA levels of these latter kinases were higher in spermatogonia and spermatocytes than in spermatids, protein levels were highest in spermatids, suggesting delayed transcript translation. Taken together, these results clearly show an uneven expression of each kinase in different spermatogenic cells, indicating that each member may play a different role during spermatogenesis, in addition to highlighting the complexity of Src-related kinase expression regulation in male germ cells. Furthermore, differential localization of these tyrosine kinases in mature spermatozoa also suggests a specific role for each member in sperm function and integrity.
Ion channels induced by the prion protein (2012)

Prion diseases comprise a group of rapidly progressive and invariably fatal neurodegenerative disorders for which there are no effective treatments. While conversion of the cellular prion protein (PrP(C)) to a β-sheet rich isoform (PrP(Sc) ) is known to be a critical event in propagation of infectious prions, the identity of the neurotoxic form of PrP and its mechanism of action remain unclear. Insights into this mechanism have been provided by studying PrP molecules harboring deletions and point mutations in the conserved central region, encompassing residues 105-125. When expressed in transgenic mice, PrP deleted for these residues (Δ105-125) causes a spontaneous neurodegenerative illness that is reversed by co-expression of wild-type PrP. In cultured cells, Δ105-125 PrP confers hypersensitivity to certain cationic antibiotics and induces spontaneous ion channel activity that can be recorded by electrophysiological techniques. We have utilized these drug-hypersensitization and current-inducing activities to identify which PrP domains and subcellular locations are required for toxicity. We present an ion channel model for the toxicity of Δ105-125 PrP and related mutants and speculate how a similar mechanism could mediate PrP(Sc)-associated toxicity. Therapeutic regimens designed to inhibit prion-induced toxicity, as well as formation of PrP(Sc) , may prove to be the most clinically beneficial.
[Transanal resection of large sessile rectal polyps]. (1996)

Transanal resection of large rectal adenomas is a safe and effective method of treatment. However, the high recurrence requires frequent endoscopy.