gebhart/patrepeval huggingface dataset:
Evaluation of in-hospital NT-proBNP changes in heart failure patients to identify the six-month clinical response following cardiac resynchronization therapy. (2014)

N-terminal pro β-type natriuretic peptide (NT-proBNP) is a valuable marker for monitoring the response to treatment in patients with heart failure. Based on the clinically observed improvement of heart failure symptoms early after cardiac resynchronization therapy (CRT), we sought to investigate whether CRT induce any significant reduction in the plasma level of NT-proBNP in three days after implantation and whether it is correlated with patients' response at six months. In this prospective study, 21 consecutive patients with severe heart failure (New York Heart Association class 3.19±0.40) who underwent CRT were enrolled. Being alive, no hospitalization due to decompensated heart failure, and improvement of at least one NYHA functional class at six months were classified as clinical responsiveness. The plasma level of NT-proBNP was measured before, three days, and six months after CRT. Clinical evaluation, echocardiographic study, and six-minute walking test were performed before and six months after the procedure. At six months' follow-up, 16 (76.2%) patients were responders. The plasma level of NT-proBNP at three days after CRT increased almost equally in both responder and non-responder groups of patients (∆NT-proBNP was 40.94±135.74 vs. 54.80±88.98); however, at six months' follow-up, the NT-proBNP changes statistically differed across the two groups of patients (P=0.005). According to our findings, NT-proBNP percent deviation from baseline to three days after CRT appears to be not correlated with the patients' clinical response after six months, which was incongruent to the patients' clinical improvement after CRT.
COLORADO MEDIAN BARRIER END TREATMENT TESTS (1981)

Two median barrier end treatment designs (type 3G and 3 F) were submitted by the Colorado Department of Highways (CDH) to the Texas Transportation Institute (TTI). After analysis and evaluation, TTI tested the type 3F end treatment design with four crash tests, modifying the design in the process. The final design was deemed acceptable for use on an experimental basis in areas where W-beam guardrails meet in the middle of divided highways. (FHWA)
Diffraction radiation by a charge sheet moving past a conducting wedge (2002)

The diffraction radiation is calculated for a charge sheet moving past a conducting wedge at the speed of light. The two-dimensional problem is analyzed in the time domain using the conical flow method which has been developed for supersonic aerodynamics. The method transforms the wave problem into a two-dimensional potential problem which subsequently is solved by conformal mapping. Field lines are shown for different geometries.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Blood DNA Methylation and Aging: A Cross-Sectional Analysis and Longitudinal Validation in the InCHIANTI Study (2020)

Changes in DNA methylation have been found to be highly correlated with aging in humans, but causes or consequences of these changes are not understood. We characterized the DNA methylomes of several hundred people in the Invecchiare in Chianti study to identify DNA sites in which percent methylation was systematically different with age. Then, we tested the hypothesis that changes of percent methylation in the same DNA sites occur longitudinally for the same DNA sites in the same subjects. We identified six differentially methylated regions in which percent methylation showed robust longitudinal changes in the same direction. We then describe functions of the genes near these differentially methylated regions and their potential relationship with aging, noting that the genes appear to regulate metabolism or cell type specificity. The nature of transcription factor binding sites in the vicinity of these differentially methylated regions suggest that these age-associated methylation changes reflect modulation of two biological mechanisms: the polycomb repressive complex 2, a protein complex that trimethylates histone H3 on lysine 27, and the transcriptional repressor CCCTC-binding factor or CTCF, both of which are regulators of chromatin architecture. These findings are consistent with the idea that changes in methylation with aging are of adaptive nature.
[Aortorenal bypass with autologous saphenous vein in Takayasu arteritis-induced renal artery stenosis: an analysis of 33 cases]. (2011)

ARB using the autologous saphenous vein graft is safe, effective and durable for treating TARAS.
Enhanced Flow Cytometry-Based Bead Immunoassays Using Metal Nanostructures (2009)

While the principle of fluorescence enhancement of metal nanostructures is well-known, the utility of this effect in practical methodologies used in analytical laboratories remains to be established. In this work, we explore the advantage of fluorescence enhancement for flow cytometry. We report the observation of metal-enhanced fluorescence emission of fluorophores located on the surface of silica beads coated with nanostructured silver, suitable for flow cytometry detection. The fluorescence enhancement was investigated using a model AlexaFluor 430 IgG immunoassay and AlexaFluor 430 labeling. Approximately 8.5-fold and 10.1-fold higher fluorescence intensities at 430 nm excitation were, respectively, observed from silvered approximately 400 nm and 5 microm silica beads deposited on glass as compared to the control sample. The 400 nm and 5 microm beads were compatible with the flow cytometry readout, although lower enhancement factors of 3.0 and 3.7 were obtained. We show that such values are consistent with less favorable overlap of the plasmon resonance in silver nanostructures with 488 nm excitation wavelength used in the flow cytometry experiment. We, thus, demonstrated that the silvered silica beads are able to provide intensified fluorescence signals in flow cytometry which can improve the sensitivity of flow cytometry-based bioassay systems.
The Caspase Selective Inhibitor EP1013 Augments Human Islet Graft Function and Longevity in Marginal Mass Islet Transplantation in Mice (2008)

Our data suggest that EP1013 therapy will markedly reduce the islet mass required in clinical islet transplantation, improving insulin independence rates following single-donor infusion.
Novel viruses of the family Partitiviridae discovered in Saccharomyces cerevisiae (2023)

It has been 49 years since the last discovery of a new virus family in the model yeast Saccharomyces cerevisiae. A large-scale screen to determine the diversity of double-stranded RNA (dsRNA) viruses in S. cerevisiae has identified multiple novel viruses from the family Partitiviridae that have been previously shown to infect plants, fungi, protozoans, and insects. Most S. cerevisiae partitiviruses (ScPVs) are associated with strains of yeasts isolated from coffee and cacao beans. The presence of partitiviruses was confirmed by sequencing the viral dsRNAs and purifying and visualizing isometric, non-enveloped viral particles. ScPVs have a typical bipartite genome encoding an RNA-dependent RNA polymerase (RdRP) and a coat protein (CP). Phylogenetic analysis of ScPVs identified three species of ScPV, which are most closely related to viruses of the genus Cryspovirus from the mammalian pathogenic protozoan Cryptosporidium parvum. Molecular modeling of the ScPV RdRP revealed a conserved tertiary structure and catalytic site organization when compared to the RdRPs of the Picornaviridae. The ScPV CP is the smallest so far identified in the Partitiviridae and has structural homology with the CP of other partitiviruses but likely lacks a protrusion domain that is a conspicuous feature of other partitivirus particles. ScPVs were stably maintained during laboratory growth and were successfully transferred to haploid progeny after sporulation, which provides future opportunities to study partitivirus-host interactions using the powerful genetic tools available for the model organism S. cerevisiae.
Uncooled infrared bolometer arrays operating in a low to medium vacuum atmosphere: performance model and tradeoffs (2007)

In this paper we present a comprehensive calculational model for the noise equivalent temperature difference (NETD) of infrared imaging systems based on uncooled bolometer arrays. The NETD model is validated and benchmarked using published performance data of state-of-the-art uncooled infrared bolometer arrays. The calculational model is used to evaluate possible infrared sensor and system design tradeoffs that allow optimization for low-cost infrared systems with improved reliability and lifetime, while still achieving a NETD of about 150 mK, required for pedestrian injury mitigation systems. We propose an approach in which high performance crystalline semiconductor materials with very low 1/f-noise properties and a temperature coefficient of resistance (TCR) of 3 %/K are used as thermistor material for the bolometers. The resulting increased bolometer performance can be used to operate the infrared imaging arrays in a vacuum atmosphere with increased gas pressure while still achieving useful NETD levels. The proposed calculational model suggests that a NETD on the order of 150 mK can be reached with uncooled infrared bolometer arrays operating in vacuum pressures on the order of 6 mbar. Such specifications for the bolometer vacuum package dramatically simplify wafer-level vacuum packaging and ease long-term reliability issues, contributing to lowering the vacuum packaging and thus, the overall infrared imaging chip costs.
Highly precise multi-cathode pulsed-DC sputtering employing digital processing–application to layer–by–layer synthesis of cubic (Er 0.1 Y 0.9 ) 2 Zr 2 O 7 thin film (2021)

Abstract A digitally processed DC reactive sputtering (DPDRS) system employing field-programmable gate-array has been developed. In this report, atomically precise pulsed-DC sputtering of a metal oxide compound, cubic (Er 0.1 Y 0.9 ) 2 Zr 2 O 7 (c-EYZO), is demonstrated by using DPDRS. An alternating process of pulsed metal sputtering and reactive gas pulsing was applied in order to realize layer-by-layer reactive sputtering. The pulsed metal sputtering separated from the oxidation process results in a stable and high deposition rate of c-EYZO at 1.9 μ m h −1 , which corresponds to 1.56 nm/cycle. By adjusting the deposition rate to the d-spacing of 0.26 nm corresponding to the (200) diffraction, layer-by-layer synthesis of a highly oriented c-EYZO thin film showing the d-spacing was achieved. X-ray diffraction and photoluminescence measurements indicate drastic improvement of the crystalline properties and the emission properties due to the layer-by-layer synthesis. It is expected that DPDRS enables arbitrarily designed atomically precise deposition of the metal oxide compound synthesis.
MuIT: An End-to-End Multitask Learning Transformer (2022)

We propose an end-to-end Multitask Learning Transformer framework, named MulT, to simultaneously learn multiple high-level vision tasks, including depth estimation, semantic segmentation, reshading, surface normal estimation, 2D keypoint detection, and edge detection. Based on the Swin transformer model, our framework encodes the input image into a shared representation and makes predictions for each vision task using task-specific transformer-based decoder heads. At the heart of our approach is a shared attention mechanism modeling the dependencies across the tasks. We evaluate our model on several multitask benchmarks, showing that our MulT framework outperforms both the state-of-the art multitask convolutional neural network models and all the respective single task transformer models. Our experiments further highlight the benefits of sharing attention across all the tasks, and demonstrate that our MulT model is robust and generalizes well to new domains. Our project website is at https://ivrl.github.io/MulT/.
Cardiomyopathy and its Various Causes Among KP Population (2019)

Background: Cardiomyopathy is an anatomic and pathological abnormality resulting in mechanical and electrical instability of the heart. It's among the leading causes of mortality and morbidity secondary to cardiac issues Objective: To determine the burden of cardiomyopathy and its different types among population of KPK. Material & Methods: This retrospective descriptive study was conducted in a private cardiology clinic from January 2018 to March 2018. Clinical and echo data from January 2015 to December 2017 was reviewed. Patients with diagnosed cardiomyopathy on echo were included in the study. Demographic data with comorbid conditions and echo data was recorded in a predesigned proforma. Data was analyzed in SPSS 20.0 with mean ± SD for continuous variables and frequency (%ages) for categorical variables. Chi-square test was applied to look for significance of disease burden with p=0.05 as significant. Results: A total of 2422 patients with mean age of 55±17.1 years were enrolled in the study, of which 46% were males, 60% were diabetic and 49% were hypertensive while 50% were suffering from depression. ICM was the leading cause of CMP among our population having a frequency of 55%, followed by post-myocarditis CMP and peripartum CMP having a frequency of 11% and 10% respectively. VHD accounted for 6% cases among CMP and HOCM 7%. Rest of CMPs were quite rare. Conclusion: CMP poses a significant disease burden in our society with ICM being the leading cause, followed by postmyocarditis CMP and peripartum CMP.
Motor unit number estimation and neuromuscular fidelity in 3 stages of sarcopenia (2016)

Unlike MU number estimates, strength and MU stability differed across groups and related to degree of sarcopenia. Muscle Nerve 55: 676-684, 2017.
Monoclonal antibody detection of heparin-binding proteins on sperm corresponds to increased fertility of bulls. (1996)

A monoclonal antibody (M1) was produced against seminal fluid heparin-binding proteins (HBP) from a vasectomized bull. In the first part of this study, the presence of HBP in sperm or seminal fluid was determined for 53 bulls with an ELISA using M1. Bulls (8 to 18 per pasture) were bred to 1,114 cows at ratios of 1 bull:25 cows. Bulls with detectable HBP on sperm membranes were 11 percentage points more fertile than bulls with undetectable HBP in sperm membranes. In the second part of this study, three sperm, membrane HBP approximately 30, 24, and 21.5 kDa were identified with Western blots using M1. Santa Gertrudis bulls (n = 64) were bred to 1,354 Santa Gertrudis cows in groups with 2 to 11 bulls. Bulls with those three HBP (Group A) or a single 30-kDa HBP (Group B) in sperm membranes had the greatest fertility, ranging from 74.4 to 89.9% (mean = 81.5%) of the palpated cows that were pregnant. Bulls with the 21.5- and 30-kDa HBP (i.e., the 24-kDa HBP was absent; Group C) had a reduced fertility of 61.3%. Bulls without detectable HBP (Group D) resulted in 41.9% of 186 cows palpated pregnant. Bulls in Groups A and B were more (P < .01) fertile than all other groups. In conclusion, the presence of HBP in sperm membranes was indicative of the fertility potential of bulls.
Maintaining Subsurface Drip Irrigation Systems (2004)

Make sure your system contains a flow meter and a couple of pressure gauges—one gauge before the filters and another after the filters. Give these devices a quick inspection every day. They indicate whether the system is working properly. A low pressure reading on a pressure gauge means that a part is leaking or a pipe is broken. A difference in pressure between the filters may mean the system is not being backflushed properly and that the filters need to be cleaned.
An Open-Source Python Library for Modeling LETID and LID in Silicon Solar Cells and Wafers (2023)

This poster demonstrates an (in development) open-source software library, written in python, to aid in modeling and understanding light- and elevated temperature-induced degradation (LETID) and boron-oxygen light-induced degradation (B-O LID) in silicon solar cells and wafers. We discuss the underlying equations and necessary input parameters for constructing realistic models. We demonstrate several use cases for the library, including modeling LETID progression in scenarios like indoor, accelerated tests and outdoor field deployment. We also demonstrate using the library to model B-O LID, and we demonstrate using the library to model degradation in passivated wafers, rather than solar cells.
Rolling Stochastic Optimization based operation of distribution systems with PVs and Energy Storages (2014)

This paper presents a novel framework for stochastic optimal operation of Energy Storage (ES) systems in coordination with Renewable Energy Resources (RERs) in three-phase unbalanced distribution systems. An efficient three-phase unbalanced Distribution Optimal Power Flow (DOPF) is formulated that can be used for both radial and meshed networks. Mathematical optimization models for ESs are developed and integrated in the DOPF formulation. Then, two stochastic operation methods, Fixed-Window Iterative and Rolling Stochastic Optimization methods, are employed to optimally schedule the operation of resources in distribution networks with uncertainties in demand and RER outputs. The proposed optimization model can also be employed to analyze the effects of integrating RERs and ESs into distribution systems. Some relevant simulation results are presented and discussed to highlight the effectiveness of the proposed method to optimally operate distribution systems with ES and RERs. Presented results show that considerable power loss reductions could be achieved with optimal operation of ESs even in the presence of uncertainties.
Interactions of Endoglucanases with Amorphous Cellulose Films Resolved by Neutron Reflectometry and Quartz Crystal Microbalance with Dissipation Monitoring (2012)

A study of the interaction of four endoglucanases with amorphous cellulose films by neutron reflectometry (NR) and quartz crystal microbalance with dissipation monitoring (QCM-D) is reported. The endoglucanases include a mesophilic fungal endoglucanase (Cel45A from H. insolens), a processive endoglucanase from a marine bacterium (Cel5H from S. degradans ), and two from thermophilic bacteria (Cel9A from A. acidocaldarius and Cel5A from T. maritima ). The use of amorphous cellulose is motivated by the promise of ionic liquid pretreatment as a second generation technology that disrupts the native crystalline structure of cellulose. The endoglucanases displayed highly diverse behavior. Cel45A and Cel5H, which possess carbohydrate-binding modules (CBMs), penetrated and digested within the bulk of the films to a far greater extent than Cel9A and Cel5A, which lack CBMs. While both Cel45A and Cel5H were active within the bulk of the films, striking differences were observed. With Cel45A, substantial film expansion and interfacial broadening were observed, whereas for Cel5H the film thickness decreased with little interfacial broadening. These results are consistent with Cel45A digesting within the interior of cellulose chains as a classic endoglucanase, and Cel5H digesting predominantly at chain ends consistent with its designation as a processive endoglucanase.
Glucosinolates in Broccoli Stored under Controlled Atmosphere (1995)

Content of total and individual glucosinolates were determined in, `Marathon' broccoli florets (Brassica olerucea L. var. italica stored 7 days at 10C under air, 0.5% O 2 , 0.5% O 2 + 20% CO 2 or 20% CO 2 atmosphere, followed by transfer to air for 2 days. `Marathon' broccoli contained glucoraphanin, glucobrassicin, neoglucobrassicin, glucoiberin, 4-methoxyglucobrassicin, progoitrin, glucoalyssin, and gluconasturtiin. The methylssulfinylalkylglucosinolates (glucoiberin and glucoraphanin) and the indol-3-ylmethylglucosinolates (glucobrassicin, neoglucobrassicin and 4-methoxyglucobrassicin) accounted for 78% and 20% of the total content, respectively, in freshly harvested broccoli. CA treatment and storage time had no significant effect on the relative content of these two groups of glucosinolates. Freshly harvested broccoli contained 47 μmol glucosinolate/g dry weight. The total glucosinolate content increased 42% and 21% during 7 days storage under air and 0.5% O 2 + 20% CO 2 , respectively, as compared to freshly harvested broccoli, and decreased 15% in broccoli stored under 20% CO 2 . Treatment with 20% CO 2 in the absence of 0, resulted in visible CO, injury and water soaking of the tissue. Aeration had no significant effect on total glucosinolate content but reduced the glucobrassicin content 35% in broccoli stored 7 days under 0.5% O 2 + 20% CO 2 or 20% CO 2 atmosphere. In contrast, the 4-methoxyglucobrassicin content increased during storage under low O 2 atmosphere and increased further after transfer to air.
Accessmonkey (2007)

This paper proposes the Accessmonkey Framework for collaborative web accessibility improvement. The goal of the system is to provide a common platform on which end users and developers can create, share and use scripts that specify accessibility improvements. We propose browser plugins that will automatically retrieve user scripts from a common repository and apply helpful transformations to pages visited by users. End user interfaces will allow anyone to create and share new improvements and developer interfaces will allow content creators to edit and save changes scripts make to web content. Accessmonkey seeks to enable those most impacted by web accessibility challenges to directly and independently improve them. This work is being pursued with close consultation and participation by blind web users.
Intramural duodenal hematoma: an unusual complication after esophagogastroduodenoscopy in an adolescent (2022)

Intramural duodenal hematoma: an unusual complication after esophagogastroduodenoscopy in an adolescent Fig.
A case of retroperitoneal liposarcoma extending through the inguinal canal to the thigh and lesser trochanter (2023)

Treatment strategies for huge retroperitoneal liposarcomas are important to balance antitumor efficacy and postoperative quality of life.
On the road to behavior-based integration (2004)

Integration of autonomous object-oriented systems requires the integration of object structure and object behaviour. Research in federated information systems has so far mainly addressed integration of object structure. The integration of object behaviour carries with it the promise to finally move integration tools beyond the state of the art at which they have (roughyl) existed for the better part of a decade, and we are embarked on a project that examines this problem in terms of object life cycles. The topic is also increasing in actuality since it also applies to the integration of business processes, which is typically required when companies merge or enter into consumer-producer relationships, and results can be expected to naturally extend to the arena of web services. Ultimately, the goal will be to define consistency criteria for behaviour integration and apply them in integration tools that guide the definition of global behavioural views upon autonomous object-oriented systems.