gebhart/patrepeval huggingface dataset:
A comparative study of helical sense and twisting power in low-molar-mass and polymeric chiral nematics (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA comparative study of helical sense and twisting power in low-molar-mass and polymeric chiral nematicsSushil Krishnamurthy and Shaw H. ChenCite this: Macromolecules 1992, 25, 18, 4485–4489Publication Date (Print):August 1, 1992Publication History Published online1 May 2002Published inissue 1 August 1992https://pubs.acs.org/doi/10.1021/ma00044a005https://doi.org/10.1021/ma00044a005research-articleACS PublicationsRequest reuse permissionsArticle Views64Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Outcome after Hemorrhagic Shock in Trauma Patients (1998)

Hemorrhage-induced hypotension in trauma patients is predictive of high mortality (54%) and morbidity. The requirement for large volumes of crystalloid was associated with increased mortality.
[Lymphocyte receptors that regulate the immune-response--the key to the management of antitumor immunity]. (2015)

Tumor uses various mechanisms to "escape" from immune surveillance including the important role of dysregulation of interaction of signals from corresponding co-stimulatory and co-inhibitory receptors (so-called "control points immunity"-- immune "checkpoints") modulating T-cell activation process. A creation of targeted drugs impacting on immune "checkpoints"" is a new promising trend in modern oncoimmunology. This review is devoted to a brief characterization of some receptors of immune competent cells (such as activation and inhibitor), which play a crucial role in the interaction of the immune system and tumors as well as targeted drugs acting on them for therapeutic purpose.
Designerly Ways of Teaching and Learning : A Course Structure for Interaction Design (2012)

Society´s use of increasingly complex information technology is, in a long-term perspective, shaped by the way we train our future designers and developers of information systems. By preparing stud ...
Application of continual injection liquid‐phase microextraction method coupled with liquid chromatography to the analysis of organophosphorus pesticides (2009)

A liquid-phase microextraction coupled with LC method has been developed for the determination of organophosphorus pesticides (methidation, quinalphos and profenofos) in drinking water samples. In this method, a small amount (3 microL) of isooctane as the acceptor phase was introduced continually to fill-up the channel of a 1.5 cm polypropylene hollow fiber using a microsyringe while the hollow fiber was immersed in an aqueous donor solution. A portion of the acceptor phase (ca. 0.4 microL) was first introduced into the hollow fiber and additional amounts (ca. 0.2 microL) of the acceptor phase were introduced to replenish at intervals of 3 min until set end of extraction (40 min). After extraction, the acceptor phase was withdrawn and transferred into a 2 mL vial for a drying step prior to injection into a LC system. Parameters that affect the extraction efficiency were studied including the organic solvent, length of fiber, volume of acceptor and donor phase, stirring rate, extraction time, and effect of salting out. The proposed method provided good enrichment factors of up to 189.50, with RSD ranging from 0.10 to 0.29%, analyte recoveries of over 79.80% and good linearity ranging from 10.0 to 1.25 mg/L. The LOD ranged from 2.86 to 82.66 microg/L. This method was applied successfully to the determination of organophosphorus pesticides in selected drinking water samples.
20/40 or Better Visual Acuity After Optic Neuritis: Not as Good as We Once Thought (P1.323) (2015)

Objective: We examined vision-specific QOL scores in an MS cohort among the specific sub-group of patients with history of ON and high-contrast VA of 20/40 or better in both eyes. Background: It has been reported that patients with acute optic neuritis (ON) have good visual recovery, with return of high-contrast visual acuity (VA) to 20/40 or better in 95[percnt] of affected eyes. Vision-specific quality of life (QOL), however, is reduced among overall cohorts of patients with history of ON, even years following the acute event. Methods: Participants in an ongoing collaborative study of MS visual outcomes completed 25-Item National Eye Institute Visual Functioning Questionnaire (NEI-VFQ-25) and 10-Item Neuro-Ophthalmic Supplement, as well as VA and low-contrast letter acuity (LCLA) testing. Spectral-domain optical coherence tomography (SD-OCT) was performed to determine peripapillary retinal nerve fiber layer thickness (RNFL) and macular ganglion cell+inner plexiform layer thickness (GCL+IPL). Results: Analyses of data from 247 patients with MS (age 47.1±11.6 years) showed that among those with a history of ON (n=128), vision-specific QOL scores were reduced compared to disease-free controls even among the sub-group with VA 20/40 or better in both eyes (n=106, p<0.001 for NEI-VFQ-25 composite and 10-Item Supplement, linear regression, accounting for age). Specifically, NEI-VFQ-25 scores were 83.6±14.7 (compared to 98.4±1.8 for controls), with Supplement scores 73.8±17.9 (vs. 96.8±4.9 for controls). Those with greater binocular LCLA had better QOL scores (2.5[percnt]: p=0.02; 1.25[percnt]: p=0.006, accounting for age). Eyes in this sub-group had significant thinning of the RNFL (79.8 vs. 93.0 microns for controls, p<0.001) and GCL+IPL (69.7 vs. 80.4 microns, p<0.001, accounting for age and within-patient, inter-eye correlations). Conclusions: Even when VA is 20/40 or better, patients with a history of acute ON are left with clinically meaningful reductions in vision-specific QOL, and manifest significant degrees of retinal axonal and neuronal loss.
Trichlorogermane, a New Superacid in Organic Chemistry (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
Network coding based multipath TCP (2012)

Multipath TCP (MPTCP) suffers from the degradation of goodput in the presence of diverse network conditions on the available subflows. The goodput can even be worse than that of one regular TCP, undermining the advantage gained by using multipath transfer. In this work, we propose a new multipath TCP protocol, namely NC-MPTCP, which introduces network coding (NC) to some but not all subflows traveling from source to destination. At the core of our scheme is the mixed use of regular and NC subflows. Thus, the regular subflows deliver original data while the NC subflows deliver linear combinations of the original data. The idea is to take advantage of the redundant NC data to compensate for the lost or delayed data in order to avoid receive buffer becoming full. We design a packet scheduling algorithm and a redundancy estimation algorithm to allocate data among different subflows in order to optimize the overall goodput. We also give a guideline on how to choose the NC subflows among the available subflows. We evaluate the performance of NC-MPTCP through a NS-3 network simulator. The experiments show that NC-MPTCP achieves higher goodput compared to MPTCP in the presence of different subflow qualities. And in the worst case, the performance of NC-MPTCP is close to that of one regular TCP.
Oncogenic Activity of Epidermal Growth Factor Receptor Kinase Mutant Alleles Is Enhanced by the T790M Drug Resistance Mutation (2007)

Activating mutations in the epidermal growth factor receptor (EGFR) characterize a subset of non-small cell lung cancers (NSCLC) with extraordinary sensitivity to targeted tyrosine kinase inhibitors (TKI). A single secondary EGFR mutation, T790M, arising in cis with the primary activating mutation, confers acquired resistance to these drugs. However, the T790M mutation is also detected in the absence of drug selection, suggesting that it may provide a growth advantage. We show here that although T790M alone has only a modest effect on EGFR function, when combined with the characteristic activating mutations L858R or del746-750, it results in a dramatic enhancement of EGFR activity. The double mutants show potent ligand-independent receptor autophosphorylation associated with altered cellular phenotypes, soft agar colony formation, and tumorigenesis in nude mice. The significant gain-of-function properties of these double mutants may explain their initial presence before drug selection and their rapid selection as the single drug resistance mutation during therapy with gefitinib/erlotinib, and suggests that they may contribute to the adverse clinical course of TKI-resistant NSCLC.
Electrochemical treatment of wastewaters (1994)

Electrochem. treatment of wastewater with the application of Ti/SnO2 anode for enhanced oxidn. of org. compds. is described. [on SciFinder (R)]
Scapular dyskinesis and SICK scapula syndrome following surgical treatment of type III acute acromioclavicular dislocations (2012)

Retrospective study, Level IV.
[Introduction of mass psychology in animals to pharmacology. 6. Mutural relation in simultaneity convulsion and non-convulsin in E1-mice]. (1970)

1) El-マウスの痙攣発症に関するマウスの2者または3者の相互関係を多数例について整理したところその不発作率と同調率の間に一定の関係が存在することがわかった． 2) この関係に対し，一般薬理作用の全く認められない微量の中枢作用薬物を予め投与しておいた場合の影響を調べた．その結果中枢興奮剤を与えた場合には同調性が多くなり，逆に中枢抑制剤を与えた場合には不発作率が大きく同調性が少なくなった． 3) amphetamine投与によって2～3者関係特に2者関係はいずれも正常範囲から外れ，しかもある一定の範囲に収束することが明らかとなった．
Elastolytic Metalloproteinases Produced by Human Mononuclear Phagocytes: Potential Roles in Destructive Lung Disease (1994)

Mononuclear phagocytes have the capacity to produce an array of MMPs. Several of these proteinases are capable of degrading insoluble elastin, an important component for the structural stability of the lung. Matrilysin is a low molecular weight proteinase with a broad substrate specificity produced at highest levels in in vitro differentiated monocytes. The 92-kD gelatinase is a major product of human alveolar macrophages that is also an elastase. The most newly described member of the MMP family is human macrophage metalloelastase. This enzyme is also expressed in alveolar macrophages derived from cigarette smokers. Determining the contribution of these and other elastolytic proteinases to the pathogenesis of emphysema is a focus of ongoing research.
Correlation Matrix Memories (1972)

A new model for associative memory, based on a correlation matrix, is suggested. In this model information is accumulated on memory elements as products of component data. Denoting a key vector by q <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">(p)</sup> , and the data associated with it by another vector x <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">(p)</sup> , the pairs (q <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">(p)</sup> , x <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">(p)</sup> ) are memorized in the form of a matrix {see the Equation in PDF File} where c is a constant. A randomly selected subset of the elements of M <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">xq</inf> can also be used for memorizing. The recalling of a particular datum x <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">(r)</sup> is made by a transformation x <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">(r)</sup> =M <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">xq</inf> q <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">(r)</sup> . This model is failure tolerant and facilitates associative search of information; these are properties that are usually assigned to holographic memories. Two classes of memories are discussed: a complete correlation matrix memory (CCMM), and randomly organized incomplete correlation matrix memories (ICMM). The data recalled from the latter are stochastic variables but the fidelity of recall is shown to have a deterministic limit if the number of memory elements grows without limits. A special case of correlation matrix memories is the auto-associative memory in which any part of the memorized information can be used as a key. The memories are selective with respect to accumulated data. The ICMM exhibits adaptive improvement under certain circumstances. It is also suggested that correlation matrix memories could be applied for the classification of data.
The Chen Shui-Bian Administrations Mainland Policy: Toward a Modus Vivendi or Continued Stalemate? (2002)

This article discusses the main elements of the Chen Shui-bian administration's cross-Strait policy, analyzes the policy's key domestic and international determinants, and offers a preliminary assessment on the policy. Chen's crossStrait policy adheres to Taiwan's "economic security" approach to national security. Whereas the previous Lee administration sought to safeguard national security by reducing economic dependence on the mainland, Chen's policy strives to normalize cross-Strait economic relations as an important pillar to peace and stability in the Taiwan Strait. Although Chen has accelerated his political maturation, his China policy continues to be constrained by various factors (most importantly, the PRC's insistence on a "one China" precondition for cross-Strait talks) and has succeeded more in reducing tensions and maintaining the status quo than in reaching a modus vivendi with the mainland. A benign stalemate without imminent military threat has ensued. Diplomatic setbacks, electoral considerations, and growing frustration with Beijing's spuming of his good will led Chen to move toward to a hardened position, such as his "Taiwan and China, each side is a country across the Taiwan Strait" formula in August 2002.
Global interconnect trade-off for technology over memory modules to application level (2003)

In this paper we show how to exploit energy-delay trade-offs that exist due to the variation of the technology parameters for the implementation of interconnect wires. We also evaluate how these trade-offs can be propagated to the memory module level, so we can minimise the power consumption of the entire memory organisation (i.e., memories and connections between them). Our approach is that at future technology nodes the delay problem can be handled at the application level, so given any delay slack obtained at that level, we can exploit it to make the switching on the interconnect wires slower and thus less energy consuming. In this way, we have shown that for real-life applications the power consumption at future technology nodes can be reduced by about 34%, when compared to the option provided by the ITRS roadmap. This is achieved by, instead of using the very fast and power hungry wires, selectively using slower and thinner interconnect wires while still meeting the application real-time constraints.
The allosteric interaction between D-galactose and the Escherichia coli galactose repressor protein. (1994)

The Escherichia coli galactose repressor protein (GalR) inhibits transcription of the gal operon upon binding to two operator sites (1-7). This DNA binding activity is inhibited when D-galactose or D-fucose binds to GalR (8-14). Fluorescence spectroscopy was used to characterize the single tryptophan of GalR and to investigate the interaction between galactose and GalR. Fluorescence quenching experiments place both tryptophan residues of the GalR dimer in similar, solvent-exposed locations. Galactose is shown to enhance the intrinsic tryptophan fluorescence of GalR, the source of which is not explained by a change in decay times, but is due to an increase in the pre-exponential factor of the longest of the three fluorescence decay times. It is shown that the beta-anomer of D-galactose is the likely form that binds to GalR. An increase in pH from 6.3 to 9.5 causes the equilibrium association constant (K alpha) describing the galactose-GalR interaction to decrease 10-fold. The interaction is cooperative below pH 9.5. Over the pH range of 6.3 to 9.5, the tryptophan solvent exposure of GalR increases. Galactose binding also induces an increase in exposure. These results, and others presented in this paper, show that both pH and galactose cause global alterations in the structure of GalR.
Selectively Catalyzed Oxidation of Benzyl Alcohol by Fe<sup>III</sup>–TAML/Hydrogen Peroxide (2015)

Benzyl alcohol was selectively oxidized to benzaldehyde with iron (III) complexed to tetra amido macrocyclic ligands (Fe III –TAML) as catalyst and 30% H 2 O 2 as oxidant. The effect of reaction temperature, reaction time, solvent, amount of catalyst and oxidant on the reaction of catalyzed oxidation of benzyl alcohol were explored. The conversion and selectivity of this oxidation reaction were calculated from calibrated GC yields of benzyl alcohol and benzaldehyde. When oxidation reaction was conducted under the conditions: solvent NMMO: ethanol = 1: 1, n (H 2 O 2 ): n (benzyl alcohol) = 2, n (catalyst): n (benzyl alcohol) = 1%, temperature 80 ̊C and reaction time 60 minutes, the conversion was 91.23% and the selectivity was 90.12%.
An Infrared Spectrophotometric Analysis for Natural Rubber in Guayule Shrubs (1982)

Abstract An accurate assay of rubber content in guayule plant tissues is essential to any genetic improvement or bioregulator program. The simpler, more rapid and less expensive the assay, the better. The several methods of rubber assay that have been used have various limitations. Earlier methods for assaying rubber content in guayule are described in two USDA reports. These are principally gravimetric methods which are tedious and relatively nonselective. One of the better ones consists in bromination of the guayule double bonds, precipitation from solution, collection, drying, and weighing the crystalline rubber bromide. This bromide method is more selective for rubber in the presence of resins than the gravimetric methods where rubber is weighed directly. For multiple and repetitive analyses, it is time consuming and somewhat unpleasant due to the recommended excess of bromine. A gravimetric method reported by Tysdal in 1951 was modified recently. The method consists of grinding guayule shrub in an efficient blender with aqueous alcohol saturated with salt. The resulting slurry is screened to recover resinous rubber particles, which are dried and weighed. Precision is considered adequate for distinguishing plants of widely differing rubber content but not for detecting incremental changes. Another rubber assay of merit is the photometric method of Traub. This volumetric method depends upon a controlled precipitation of rubber particles from solution and the determination of rubber quantity by photometric measurement of the resulting turbidity. It is being used with some modifications on a guayule breeding project at the Los Angeles State and County Arboretum Research Laboratory. The principal improvement consists in extracting the rubber from the plant tissue by homogenizer milling in solvent rather than lengthy soxhlet extractions.
Identification of a T-helper cell epitope on the rotavirus VP6 protein (1997)

In this work, we have studied the T-helper (Th)-cell response against rotavirus, in a mouse model. Adult BALB/c mice were inoculated parenterally with porcine rotavirus YM, and the Th-cell response from spleen cells against the virus and two overlapping fragments of the major capsid protein VP6 (VP6(1-192) and VP6(171-397)) were evaluated in vitro. The Th cells recognized the YM virus and the two protein fragments, suggesting that there are at least two Th-cell epitopes on the VP6 molecule. To study the specificity of Th cells against VP6 at the clonal level, we established two Th-cell hybridomas cross-reactive for the VP6 protein of rotavirus strains YM and SA11. Both hybridomas recognized the VP6(171-397) polypeptide, and a synthetic peptide comprising the amino acids 289 to 302 (RLSFQLVRPPNMTP) of YM VP6 in the context of the major histocompatibility complex class II IEd molecule. The Th-cell hybridomas recognized rotavirus VP6 in a highly cross-reactive fashion, since they could be stimulated by eight different strains of rotavirus, including the murine rotavirus EDIM, that represent five G serotypes and at least two subgroups. The amino acid sequence of the VP6 epitope is highly conserved in most group A rotavirus strains sequenced so far. On the other hand, it was found that Th cells specific for the VP6 epitope may constitute an important proportion of the total polyclonal Th-cell response against rotavirus YM in spleen cells. These results demonstrate that VP6 can be a target for highly cross-reactive Th cells.
Reaction of Bone to Methacrylate after Hip Arthroplasty (1974)

Twenty-eight bone specimens containing the implant beds of partial and total hip arthroplasties were studied. All cases of infection of the prosthesis bed and of pathological fractures due to metastasis were excluded. There was necrosis around the acrylic cement (up to three weeks postoperatively), followed by repair of the implant bed (up to two years postoperatively), and finally by bone remodeling (after completion of the repair). Microscopic acrylic pearls were found in the implant bed, documenting possible harmful alterations of the cement surface. Early and late loosening of the prosthesis may be associated with characteristic changes of the implant bed.
Moving with the Times – A New A level Further Mathematics Unit: Further Pure Mathematics with Technology (FPT) (2013)

Mathematics in Education and Industry (MEI) celebrate 50 years of existence in 2013. Over that time much has changed in the world of education, but MEI continue to play its part in being innovative in developing support for the teaching and learning of mathematics. In this article a new A level module that utilizes computer algebra systems is introduced. Its development and the wider implications for this use of technology are given.
Are we using enough listeners? no! — an empirically-supported critique of interspeech 2014 TTS evaluations (2015)

Tallying the numbers of listeners that took part in subjective evaluations of synthetic speech at Interspeech 2014 showed that in more than 60% of papers conclusions are based on listening tests with less than 20 listeners. Our analysis of Blizzard 2013 data shows that for a MOS test measuring naturalness a stable level of significance is only reached when more than 30 listeners are used. In this paper, we set out a list of guidelines, i.e., a checklist for carrying out meaningful subjective evaluations. We further illustrate the importance of sentence coverage and number of listeners by presenting changes to rank order and number of significant pairs by re-analysing data from the Blizzard Challenge 2013.