gebhart/patrepeval huggingface dataset:
Generation of immunocompatible cardiac myocytes for heart repair (2011)

Background Repair of myocardia with stem cell derived cardiomyocytes (SC-CM) is becoming increasingly realistic, although major obstacles still exist, including immunorejection of the grafts. Expression of MHC class I (MHC-I) molecules by grafted cells is the main reason for rejection. Downregulation of MHC molecules in SC-CM should reduce the immunogenicity of these cells. Results Cardiomyocytes were derived from mouse embryonic SC (CorAt) in which puromycin resistance gene was driven by a cardiac-specific promoter. CorAt formed beating cardiomyocytes and expressed cardiac specific proteins. The effect of inflammatory stimuli on the expression of MHC-I molecules was mimicked by IFN-gamma treatment. MHC-I expression was reduced by RNA interference against beta2-microglobulin (light chain) as measured by qPCR. Transduction of CorAt with anti-beta2-microglobulin shRNA lentivirus led to a lowered activation of cognate T-cells when MHC-I downregulated CorAt were used as targets. Similar results were obtained with W19 fibroblasts, confirming that analogous strategy can be used for a variety of cells. Conclusions The CorAT cells were effective in the repair of ischemic myocardia of syngeneic mice. Making these cells immunocompatible with allo- or xenogeneic recipients offers a reliable source of ESC-CM for small rodents and can be extended to ESC of large mammals for human heart repair.
Group management for mobile Ad Hoc networks (2005)

Mobile ad hoc networks (MANET) offer a convenient basis toward realization of pervasive computing, due to its ease of deployment and inherent support for anytime, anywhere network access for mobile users. However, the development of applications over such networks is faced by the challenge of network dynamics attributed to node mobility and the scalability issue. Group management poses as a promising paradigm to ease the development of distributed applications for dynamic, mobile networks. Specifically, group management makes transparent the failures due to node mobility and assembles mobile nodes to meet target functional and non-functional properties. Various network-level grouping schemes over MANET have been investigated over the last couple of years. In this paper, we introduce the design and implementation of a generic group service for MANET, defined with respect to the various attributes of relevance. Generic group management is further demonstrated with its support of scalable service discovery in MANET.
Velocity Field Measurements Over A Lex/Delta Wing By Triple Axis Hot-Film Anemometry (2003)

연장된 앞전을 갖는 삼각날개 위에서 시위방향의 여러 위치에서 3축 hot 필름 풍속계를 사용하여 속도장 데이터를 획득하였다. 속도장 데이터는 받음각 24도와 32도에 대하여 중심 시위선을 기준으로 한 레이놀즈수 <TEX>$1.76{\times}10^6$</TEX>에서 날개면에 수직한 유동단면에서 측정하였다. 3축 hot 필름 프로브에 의한 세 가지 속도 성분을 측정함으로써 연장된 앞전을 갖는 삼각날개에서의 와류장을 정량적으로 분석할 수 있었다. 날개 와류와 LEX 와류는 평균 축방향 속도가 국소 최고 속도를 갖는 영역에 존재하였다. 아울러, 앞전 근처의 날개면 위에서 주와류와 반대 방향으로 회전하는 이차와류의 생성을 관찰할 수 있었다. 측정 프로브의 유동장에의 삽입은 와류 중심 위치에 크게 영향을 주지 않음을 알 수 있었다. Velocity data were acquired at a series of stations in the chordwise direction above a delta wing with leading edge extension, using a triple axis hot film anemometry. Surveys normal to planform yield velocity field data at incidence angle of 24<TEX>$^{\circ}$</TEX>and 32<TEX>$^{\circ}$</TEX>at a centerline chord Reynolds number of <TEX>$1.76{\times}10^6$</TEX>. Experimental results of velocity measurements of mean velocity of three components gave a confidence to quantitative investigate the vortical flow field over a LEX-delta wing with this probe. The present experiments indicated the existence of both wing and LEX vortex where the local mean axial velocity is maximum. It also shown the development of secondary vortex of opposite sign of rotating above the wing surface near the leading edge. The insertion of probe across the flow field was found to have little influence on the position of the vortex core.
Gentamicin loading of calcium phosphate implants: implications for cranioplasty (2019)

Out of the three materials studied, only CaP could be loaded with gentamicin. An initial loading concentration of 400 μg/ml appears to establish an effective gentamicin concentration, possibly translating into a clinical benefit in cranioplasty.
Ingreso y alimentación de la población en el México del siglo XX (2001)

Aun cuando estamos comenzando el tercer milenio, el ser humano se sigue debatiendo entre la abundancia de alimentos y el reparto desigual de los mismos. Los patrones alimentarios experimentan cambios acordes a las tendencias globalizadoras, controlados por grandes corporaciones alimentarias que homogeneizan las formas de produccion y los habitos de consumo. El siglo XX engendro en este renglon un conflicto de intereses de mercado. Por un lado, estan las potencias agricolas que manipulan los precios y la existencia de los alimentos disponibles, y por el otro, los paises pobres dependientes de los suministros externos, lo que incide directamente en su economia y soberania internas, y los ha mantenido en un estado latente de desnutricion, que en casos como Mexico, afecta a mas de la mitad de sus habitantes. 
El consumo de alimentos es una variable necesaria para medir las asimetrias sociales si estas se originan por una distribucion inequitativa de la riqueza. Una relativa estabilidad en el ingreso permite diversificar la alimentacion, mejores posibilidades nutricionales y un incremento en la calidad de la dieta. El perfil alimentario de la poblacion tiene una amplia relacion con las posibilidades del ingreso, aunque no necesariamente un nivel economico alto determina una alimentacion adecuada
An interactive speech coding tool using LabVIEW&#x2122; (2011)

Code Excited Linear Prediction (CELP) is a closed-loop analysis-by-synthesis speech coding algorithm that has been standardized in Federal Standard-1016. Variants of the CELP algorithm form the core of many speech coding standards that exist today. In this paper, we discuss the development of an interactive speech coding tool in National Instruments LabVIEW™ software for the Federal Standard-1016 CELP algorithm. A brief description of the speech coding algorithm and the features of the LabVIEW speech coding tool are presented. Illustrations demonstrating the use of the interactive software tool in analyzing the speech coding algorithm are provided. This tool can be used to teach the various modules of the CELP based speech coders to undergraduate and graduate students.
Genital herpes evaluation by quantitative TaqMan PCR: correlating single detection and quantity of HSV-2 DNA in cervicovaginal lavage fluids with cross-sectional and longitudinal clinical data (2010)

Single qPCR measurement of HSV DNA in CVL fluids of women with chronic HSV-2 infection provided useful information for assessing GH in the setting of infrequent sampling of specimens. Observed positive correlation of the presence and quantity of HSV-2 DNA with the presence of active and more severe course of HSV-2 infection may have clinical significance in the evaluation and management of HSV-2 infected patients.
Re: Spermatogonial Stem Cell Preservation and Transplantation: From Research to Clinic (2013)

No AccessJournal of UrologyAdult Urology1 Jan 2014Re: Spermatogonial Stem Cell Preservation and Transplantation: From Research to Clinic Craig NiederbergerMD Craig NiederbergerCraig Niederberger More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2013.10.015AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Re: Spermatogonial Stem Cell Preservation and Transplantation: From Research to Clinic." The Journal of Urology, 191(1), p. 182 © 2014 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 191Issue 1January 2014Page: 182Supplementary Materials Advertisement Copyright & Permissions© 2014 by American Urological Association Education and Research, Inc.MetricsAuthor Information Craig Niederberger More articles by this author Expand All Advertisement Loading ...
Aerosol Formation from Gaseous Air Pollutants (1960)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAerosol Formation from Gaseous Air PollutantsManfred Prager, Edgar Stephens, and William ScottCite this: Ind. Eng. Chem. 1960, 52, 6, 521–524Publication Date (Print):June 1, 1960Publication History Published online1 May 2002Published inissue 1 June 1960https://pubs.acs.org/doi/10.1021/ie50606a034https://doi.org/10.1021/ie50606a034research-articleACS PublicationsRequest reuse permissionsArticle Views64Altmetric-Citations25LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Conserved Fungal LysM Effector Ecp6 Prevents Chitin-Triggered Immunity in Plants (2010)

Multicellular organisms activate immunity upon recognition of pathogen-associated molecular patterns (PAMPs). Chitin is the major component of fungal cell walls, and chitin oligosaccharides act as PAMPs in plant and mammalian cells. Microbial pathogens deliver effector proteins to suppress PAMP-triggered host immunity and to establish infection. Here, we show that the LysM domain-containing effector protein Ecp6 of the fungal plant pathogen Cladosporium fulvum mediates virulence through perturbation of chitin-triggered host immunity. During infection, Ecp6 sequesters chitin oligosaccharides that are released from the cell walls of invading hyphae to prevent elicitation of host immunity. This may represent a common strategy of host immune suppression by fungal pathogens, because LysM effectors are widely conserved in the fungal kingdom.
Two-photon and three-photon absorption coefficients of InSb (1986)

The two-photon absorption coefficient β of intrinsic InSb and the three-photon absorption coefficient γ of doped InSb were measured with high-intensity picosecond CO2 laser pulses. The picosecond duration permitted the determination of the multiphoton absorption coefficients without interference from carrier recombination and diffusion. Moreover, free-carrier absorption was made use of explicitly to enhance the absorption of the laser beam, permitting a more accurate measurement of these coefficients. The values of β and γ were found to be 2.5 cm/MW and 0.2 cm3/MW2, respectively. These values are compared with theoretical calculations in the literature.
Increased expression of the ubiquitin – proteasome pathway in murine myotubes by proteolysis-inducing factor (PIF) is associated with activation of the transcription factor NF-κB (2003)

Proteolysis-inducing factor (PIF), isolated from a cachexia-inducing murine tumour, has been shown to stimulate protein breakdown in C(2)C(12) myotubes. The effect was attenuated by the specific proteasome inhibitor lactacystin and there was an elevation of proteasome 'chymotrypsin-like' enzyme activity and expression of 20S proteasome alpha-subunits at concentrations of PIF between 2 and 16 nM. Higher concentrations of PIF had no effect. The action of PIF was attenuated by eicosapentaenoic acid (EPA) (50 microM). At a concentration of 4 nM, PIF induced a transient decrease in IkappaBalpha levels after 30 min incubation, while no effect was seen at 20 nM PIF. The level of IkappaBalpha, an NF-kappaB inhibitory protein, returned to normal after 60 min. Depletion of IkappaBalpha from the cytosol was not seen in myotubes pretreated with EPA, suggesting that the NF-kappaB/IkappaB complex was stabilised. At concentrations between 2 and 8 nM, PIF stimulated an increased nuclear migration of NF-kappaB, which was not seen in myotubes pretreated with EPA. The PIF-induced increase in chymotrypsin-like enzyme activity was also attenuated by the NF-kappaB inhibitor peptide SN50, suggesting that NF-kappaB may be involved in the PIF-induced increase in proteasome expression. The results further suggest that EPA may attenuate protein degradation induced by PIF, at least partly, by preventing NF-kappaB accumulation in the nucleus.
Discovering Unmapped Molecular Targets for Novel Covalent Drugs (2022)

Covalent drugs are molecules that irreversibly bind to specific, targeted sites in the body. They work to inhibit the disease-causing functions of certain proteins by preventing them from interacting with other substances. This is a highly promising field of drug development and the focus of Dr Mikail Abbasov from Cornell University, New York, USA. By creating and utilising new technologies and through collaborative research, Dr Abbasov has mapped novel molecular targets for potential covalent drugs to treat ailments ranging from cancer to autoimmune diseases.
Transformation of aluminium fractions and phosphorus availability in acid soils as the result of microbes and ameliorant addition (2020)

Soil acidity and problems related to aluminium (Al) toxicity are usually limiting factors for soil use in agriculture. Problems with acid soils can be overcome by liming. Another potential way to overcome problems of acid soils is to utilize young coal enriched with sulfate-reducing bacteria (SRB) or Acidithiobacillus ferrooxidans . The purpose of this study was to assess the utilization of coal enriched with SRB or A. ferrooxidans as an alternative ameliorant to provide transformation of aluminium fractions and phosphorus availability in acid soils. There were two acid soils (Ultisols) studied with differences in the content of exchangeable Al. Al fraction was differentiated into exchangeable Al (Al-exch), crystalline Al (Al-dithionite), non-crystalline Al (Al-o), organic Al bound (Al-p), non-crystalline inorganic Al (Al-po), as low or medium complex with organic matter (Al-Cu), highly stabilized Al complex with organic matter (Al-pCu). The results showed that for acid soils from Jasinga West Java and Lebak Banten, coal or lime ameliorant, microbial A. ferrooxidans or sulfate-reducing bacteria (SRB) and coal or lime ameliorant enriched with A. ferrooxidans or sulfate-reducing bacteria (SRB) significantly affected the value of Al fraction. Coal or lime ameliorant enriched with A. ferrooxidans could reduce the Al fraction content in acid soils. Coal or lime ameliorant enriched with SRB could increase the availability of P in acid soil from Jasinga West Java with the distribution of Al-pCu &gt; Al-dhitionite &gt; Al-po &gt; Al-exch &gt; Al-Cu fraction. Coal or lime ameliorant enriched with SRB could increase the availability of P in acid soil from Lebak Banten with the distribution of Al-pCu &gt; Al-po &gt; Al-dhitionite &gt; Al-Cu&gt; Al-exch
Bioinformatics analysis of epitope-based vaccine design against the novel SARS-CoV-2 (2020)

B-cell epitopes on spike protein and T-cell epitopes within nucleocapsid protein were identified and recommended for developing a protective vaccine against SARS-CoV-2.
Enhancement of Refractive Index Sensitivity by Bending a Core-Offset In-Line Fiber Mach–Zehnder Interferometer (2019)

We proposed a bent core-offset in-line fiber Mach-Zehnder interferometer for refractive index (RI) sensing. It was fabricated by the splicing method and consists of a standard single-mode fiber sandwiched between two core-offset joints, with a core-offset distance of about 6 μm. The RI sensing performance of this so-obtained interferometer was evaluated and compared with that of straight ones. Straight interferometers exhibited a relatively low sensitivity (15.326 nm/RIU), inadequate for RI measurements. However, this sensitivity was greatly improved by simply bending them into U-shaped probes. The RI sensitivity was enhanced as the curvature radius was reduced; the highest sensitivity (358.039 nm/RIU) was achieved with an interferometer having a length of 30 mm and a bend radius of 16.42 mm. Hence, the experimentally confirmed high sensitivity of our proposed sensor, combined with its simple and compact structure, easy fabrication, and low cost, makes it a promising candidate for RI sensing applications.
Effect of batch extraction conditions on yield of soluble solids from rooibos tea (1988)

Summary Extraction of soluble solids from rooibos tea (Aspalathus linearis) was investigated by single stage batch extraction. The effect of extraction temperature, extract: tea mass ratio and flow rate of water on extract concentration and yield of soluble solids was determined. Extract concentration and yield increased linearly with increase in temperature from 23 to 90°C. Increasing the mass ratio from 5:1 to 10:1 decreased extract concentration, but increased yield. Both extract concentration and yield decreased with an increase in flow rate from 0.1 to 0.2 m 3 /hr. The water‐soluble solid content of rooibos tea leaf was 21.74%, 75.1% of which was extracted at 90°C, mass ratio 10:1 and flow rate 0.1 m 3 /hr.
Statistical approach to X-ray CT imaging and its applications in image analysis. II. A new stochastic model-based image segmentation technique for X-ray CT image (1992)

For pt.I, see ibid., vol.11, no.1, p.53.61 (1992). Based on the statistical properties of X-ray CT imaging given in pt.I, an unsupervised stochastic model-based image segmentation technique for X-ray CT images is presented. This technique utilizes the finite normal mixture distribution and the underlying Gaussian random field (GRF) as the stochastic image model. The number of image classes in the observed image is detected by information theoretical criteria (AIC or MDL). The parameters of the model are estimated by expectation-maximization (EM) and classification-maximization (CM) algorithms. Image segmentation is performed by a Bayesian classifier. Results from the use of simulated and real X-ray computerized tomography (CT) image data are presented to demonstrate the promise and effectiveness of the proposed technique.
The Impact of Relative Standards on the Propensity to Disclose (2012)

Two sets of studies illustrate the comparative nature of disclosure behavior. The first set investigates how divulgence is affected by signals about others’ readiness to divulge, and shows a “herding” effect: Survey respondents are more willing to divulge sensitive information when told that previous respondents have made sensitive disclosures (Study 1A). We provide evidence of the process underlying this effect and rule out alternative explanations, by showing that information on others’ propensity to disclose affects respondents’ discomfort associated with divulgence (Study 1B), but not their interpretation of the questions (Study 1C). The second set of studies investigates how divulgence is affected by the order in which inquiries of varying intrusiveness are made, and suggests that divulgence is anchored by the initial questions in a survey; people are particularly likely to divulge when questions are presented in decreasing order of intrusiveness, and less likely when questions are presented in increasing order (Study 2A). We show that the effect arises by affecting people’s judgments of the intrusiveness of the inquiries (Study 2B). The effect is altered when, at the outset of the study, privacy concerns are primed (Study 2C), and when subjects are made to consider the relative intrusiveness of a different set of questions (Study 2D). This research helps to understand how consumers’ propensity to disclose is affected by continual streams of requests for personal information, and by the equally unavoidable barrage of personal information about others.
Two cases of intravascular papillary endothelial hyperplasia. (2000)

Intravascular papillary endothelial hyperplasia (IPEH) is a benign vascular lesion resembling hemangioma It rarely occurs in the oral mucosa and is histologically characterized by the papillary proliferation of endothelial cells during thrombus organization.We report two cases of IPEH on the lower lip and the tongue. Because the lesion grows gradually, surgical excision is the treatment of choice.
ESTUDIO TÉCNICO, MORFOLÓGICO Y COMPOSITIVO DE LAS CAPAS PICTÓRICAS CONTEMPORÁNEAS SOBRE TABLERO CONTRACHAPADO (2015)

[EN] Abstract\nSince the mid 20th century art production is marked by a great creative diversity and the new technological and innovative proposals. As a result of this creative process, the artist endorses many completely new materials, usually no directly related to traditional techniques. They are fre-quent art crafts including wood products as substrates for acrylic and vinyl paint layers. Neverthe-less, the scientific literature shows very few studies for characterization of their relationships, di-mensional stability and durability. Based on the state-of-the-art, this doctoral thesis focuses on the study of plywood boards as substrate for acrylic and polyvinyl acetate paint layers (PVAc) against accelerated aging tests, both natural and artificial as well. Thus, the main objective is to study the influence of plywood on the acrylic and vinyl paint layers by analyzing changing processes of de-gradation, discoloration and dimensional stability that occurs with contemporary artworks. Fourier Transform Infrared Spectroscopy (FTIR) has been sued for the characterization of a wide range of representative samples. Furthermore, tests have been conducted to study the most relevant mechani-cal properties of the samples as well as of the paint layers. Degradation processes of painted and not paints samples have been also carried out. To do this, both natural and artificial accelerated aging natural tests have been developed in the labs. Thus, the research has been oriented to analyses indi-vidually and combined degradation parameters acting on the natural or artificial surface degradation, such as aging effects of light, temperature and relative humidity.\nIn the chemical composition of the coloured paints, the synthetic resins are mainly styrene-acrylic and polyvinyl acetate for the undercoats, as well as acrilicato-butyl methacrylate (BA-MMA), with specific degradation processes such as bond cleavage or formation of metal soaps. Moreover, this study has also addressed the degradative effects of light on acrylic painting surfaces. This research was performed using aggressive wave lengths and tests with artificial xenon light or even natural sunlight. The portion of ultraviolet UVB and UVA lamps has been also used in the lab. The results obtained indicate that the plywood substrate does not significantly influence the degradation effects, quite the opposite that occurs with the kind of primer. The research has also evaluated the thermo-hygrometric effects, characterizing fatigue and dimensional stability of the samples, as well as the deformations depending on the primer type used. The results of this analysis suggest that, on a support of plywood, gesso primers are more stable and rigid than latex primers, mainly depending on humidity and temperature. These two parameters affect significantly both the hygroscopic and the dimensional fatigue of the samples.