gebhart/patrepeval huggingface dataset:
Delayed onset of paralysis and slowed tumor growth following in situ placement of recombinant human bone morphogenetic protein 2 within spine tumors in a rat model of metastatic breast cancer (2012)

This study shows that the local administration of rhBMP-2 (15 μg, 10 μl of 1.5-mg/ml solution) in a rat spine tumor model of breast cancer not only fails to stimulate local tumor growth, but also decreases local tumor growth and delays the onset of paresis in rats. This preclinical experiment is the first to show that the local placement of rhBMP-2 in a spine tumor bed may slow tumor progression and delay associated neurological decline.
Physical Layer Measurements for an 802.11 Wireless Mesh Network Testbed (2011)

Physical layer measurements for an infrastructure 802.11 Multichannel MultiBand Wireless Mesh Network testbed are described. Each wireless router node design consists of a Linux processor with multiple 802.11b/g transceivers operating in the 5 GHz band for backhauling, and multiple 802.11 transceivers in the 2.4 GHz band for end-user service. Each transceiver consists of a MAC and base-band processor (BBP) in addition to a radio. A Linux-based device driver has been modified to adjust the physical layer parameters. The 802.11 standard specifies three orthogonal channels, 1, 6, and 11. The routers can be programmed to implement any static mesh binary tree topology by assigning orthogonal frequency-division multiplexing (OFDM) channels to network edges. The routers can be programmed to implement any general mesh communication topology by using a time division multiple access (TDMA) frame schedule, and assigning OFDM channels to network edges within each TDMA frame. Preliminary measurements of co-channel interference and the signal to interference and noise (SINR) ratio for the network testbed are presented, using omni-directional antenna and the 802.11b operation mode. This data can be used to optimize the performance of large infrastructure Wireless Mesh networks using 802.11 technology. Index Terms—wireless mesh network; 802.11; co-channel in- terference; noise; SINR;
Optical activity based on macromolecular asymmetry (1985)

Optically active isotactic polychloral was prepared in which the optical activity comes exclusively from molecular asymmetry (i.e., helical conformation). Molecular asymmetry requires a high conformational energy barrier for the polymer backbone, and an asymmetric initiator to induce a predominance of one helical screw-sense. Polychloral meets the criteria. Asymmetric initiators used to obtain optically active polychloral include tetramethyl ammonium (+)- or (−)-0-acetylmandelate, tetramethylammonium (+)- or (−)-0-methylmandelate, the lithiumalkoxides of methyl (+)- or (−)-mandelate, lithium cholesten-3β-oxide, lithium cholestan-3β-oxide, and lithium (+)- or (−)-2-octanoxide. Using the above initiators at 0.5 mol %, a maximum specific rotation of [α] D25 = 5000 was obtained for polychloral. Errors in specific rotation were typically ±7%.
Performance Gains for Rotary Steerable Through Specialized Bit Design (2005)

This paper presents an updated matched drilling approach that significantly improves directional control by selecting appropriate bit side cutting aggressiveness to the rotary steerable system (RSS). This reduces vibrations and makes directional control easier. By reducing the wasted drilling energy that is consumed in downhole vibrations, directional control and penetration rates on field studies of several runs in deepwater Brazil were improved. The paper traces the application process of selecting bit features for a push-the-bit rotary steerable application by assessing active versus passive gauge cutters, geological conditions, anomalies, and objectives. The timeline for bit design, manufacture, and field application explains how an oil company was able to drill wells that previously had presented directional difficulties. The findings of the paper are based on an evaluation of PDC rotary steerable bits by a directional company that ranked bit stability and dogleg generation as two key criteria for performance. The recommendation shows the bit design that performs best in the field conditions observed and the use of measurement-while-drilling mechanical measurements to improve the evaluation process.
Follow-up after abortion. (1969)

on this subject provoked a disappointingly short correspondence.Like
Generation of Thiolsulfinates/Thiolsulfonates by Electrooxidation of Thiols on Silicon Surfaces for Reversible Immobilization of Molecules (2003)

This work describes a method for immobilization of biomolecules on surfaces via electrooxidation of surface thiols by generating thiolsulfinates/thiolsulfonates that display a high reactivity toward free thiols in molecules. This is done by applying a potential difference between a platinum cathode and a thiol-derivatized silicon surface as the anode, through a buffer solution. X-ray photoelectron spectroscopy data showed that the amount of thiolsulfinates/thiolsulfonates was voltage dependent. When a potential difference of 1.0 V was applied between the silicon surface and the platinum electrode for 1 min, about 80% of the thiols were converted to thiolsulfonates/thiolsulfinates. The results of comparative chronoamperometric experiments, using a three-electrode potentiostatic setup, indicate that the thiols are oxidized electrochemically at +0.6 V versus Ag/AgCl. This indicates the presence of a direct electrochemical oxidation of the thiols on the silicon surface rather than an oxidation of the thiols by, for example, oxygen formed during the oxidation of water. Peptides containing thiol groups were subsequently covalently bound to the surface through disulfide bonds involving 25% of the thiolsulfinates/thiolsulfonates, which indicates a fully saturated surface coverage with peptide molecules. It was possible to release 40% of the peptides using dithiothreitol. When a voltage was applied to such a surface for a second time, additional thiolsulfinates/thiolsulfonates were formed. This method, used together with nanosized electrodes or a scanning probe microscope tip as a counter electrode, will allow a spatially controlled immobilization of biomolecules on surfaces at the nanometer scale.
Relationship between admission serum sodium concentration and clinical outcomes in patients hospitalized for heart failure: an analysis from the OPTIMIZE-HF registry (2007)

Hyponatraemia in hospitalized patients with heart failure is relatively common and is associated with longer hospital stays and higher in-hospital and early post-discharge mortality. Re-admission rates were equally high in patients with or without hyponatraemia.
Wetting behavior of selected crude oil/brine/rock systems. Topical report, March 1, 1995--March 31, 1996 (1996)

Previous studies of crude oil/brine/rock (COBR) and related ensembles showed that wettability and its effect on oil recovery depend on numerous complex interactions. In the present work, the wettability of COBR ensembles prepared using Prudhoe Bay crude oil, a synthetic formation brine, and Berea Sandstone was varied by systematic change in initial water saturation and length of aging time at reservoir temperature (88 C). All displacement tests were run at ambient temperature. Various degrees of water wetness were achieved and quantified by a modified Amott wettability index to water, the relative pseudo work of imbibition, and a newly defined apparent advancing dynamic contact angle. Pairs of spontaneous imbibition (oil recovery by spontaneous imbibition of water) and waterflood (oil recovery vs. pore volumes of water injected) curves were measured for each of the induced wetting states. Several trends were observed. Imbibition rate, and hence water wetness, decreased with increase in aging time and with decrease in initial water saturation. Breakthrough recoveries and final oil recovery by waterflooding increased with decrease in water wetness. Correlations between water wetness and oil recovery by waterflooding and spontaneous imbibition are presented.
Highly Loaded LPC Blade and Non Axisymmetric Hub Profiling Optimization for Enhanced Efficiency and Stability (2011)

The present contribution fits into the frame of the ongoing 7th Framework European Project DREAM (valiDation of Radical Engine Architecture systeMs). One of its main themes targets the development of contra-rotating open rotors with variable pitch blades which are known to provide 10 to 15% fuel burn reduction but are noisier than high by-pass turbofans. More specifically, the present research was conducted in the frame of work package 3.4 lead by Techspace Aero, dedicated for one part to the design of a high speed booster adapted to open rotor configurations, and for the second part, from which this paper is issued, to the investigation of 3D geometries to improve LPC efficiency. A reference rotor blade has first been designed, with high loading, especially at hub. To improve its efficiency, a backward sweep has then been applied as it tends to unload midspan sections. However, this performance gain came at the price of severe stall margin degradation, the criticality of the hub region being increased. Based on 1.5 stage 3D RANS simulations, automated surrogate-assisted optimization has then been exploited to respectively evaluate the potential benefit of tailored 2D contouring and 3D hub profiling a posteriori applied to the swept rotor blade and of joint 3D hub profiling and sweep optimization of the unswept baseline rotor blade. The potential benefit of 3D profiling will be demonstrated while the joint 3D profiling and blade stacking optimization shed light on the achievable interesting 3D effects combinations.
Heterodyne detection of parametric interaction in a single-mode fiber (1986)

Parametric amplification through four-wave mixing of three interacting beams in an optical fiber has been intensively investigated in recent years.1 It has been shown that large amplification values and large frequency shifts may be obtained. We study the parametric interaction which occurs between a carrier and the sidebands of a weakly modulated signal propagating in a single-mode optical fiber. We show that the gain for the sidebands depends strongly on the relative phase between the two sidebands and linearly on the pump power and interaction length.
178: Adenosine Receptors-Mediated Regulation of Micturition Reflex in Urethane-Anesthized Rats (2006)

You have accessJournal of UrologyDiscussed Poster, Sunday, May 21, 2006, 9:00 am - 12:00 pm1 Apr 2006178: Adenosine Receptors-Mediated Regulation of Micturition Reflex in Urethane-Anesthized Rats Yukio Hayashi, Kouichi Takimoto, Vickie Erickson, Sara Bacvinskas, Michael B. Chancellor, William C. de Groat, and Naoki Yoshimura Yukio HayashiYukio Hayashi More articles by this author , Kouichi TakimotoKouichi Takimoto More articles by this author , Vickie EricksonVickie Erickson More articles by this author , Sara BacvinskasSara Bacvinskas More articles by this author , Michael B. ChancellorMichael B. Chancellor More articles by this author , William C. de GroatWilliam C. de Groat More articles by this author , and Naoki YoshimuraNaoki Yoshimura More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)32445-5AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "178: Adenosine Receptors-Mediated Regulation of Micturition Reflex in Urethane-Anesthized Rats." The Journal of Urology, 175(4S), p. 58 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 175Issue 4SApril 2006Page: 58 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Yukio Hayashi More articles by this author Kouichi Takimoto More articles by this author Vickie Erickson More articles by this author Sara Bacvinskas More articles by this author Michael B. Chancellor More articles by this author William C. de Groat More articles by this author Naoki Yoshimura More articles by this author Expand All Advertisement PDF DownloadLoading ...
An Intelligent Power Electronic System for Secondary Use Batteries (2022)

This paper presents a plug-and-play power electronic system for integration of multiple energy storage system technologies. The system uses a communication and control architecture with individual developed modules to support scaling to larger systems for the electric grid. An optimization framework is also presented to demonstrate the functionality of the system. This system is shown to work in hardware with a constructed testbed to demonstrate different use cases and systems. Results are presented for a full efficiency cycle test.
Is Organic Chemistry Really Growing Exponentially? (2021)

Abstract In terms of molecules and specific reaction examples, organic chemistry features an impressive, exponential growth. However, new reaction classes/types that fuel this growth are being discovered at a much slower and only linear (or even sublinear) rate. The proportion of newly discovered reaction types to all reactions being performed keeps decreasing, suggesting that synthetic chemistry becomes more reliant on reusing the well‐known methods. The newly discovered chemistries are more complex than decades ago and allow for the rapid construction of complex scaffolds in fewer numbers of steps. We study these and other trends in the function of time, reaction‐type popularity and complexity based on the algorithm that extracts generalized reaction class templates. These analyses are useful in the context of computer‐assisted synthesis, machine learning (to estimate the numbers of models with sufficient reaction statistics), and identifying erroneous entries in reaction databases.
Gearbox fault diagnosis using vibration and current information fusion (2016)

This paper proposes a novel vibration and current information fusion-based fault diagnostic method for drivetrain gearboxes. First, two multiclass support vector machines (SVMs) are designed to output the probabilities of different fault (or health condition) classes according to the input features extracted from a vibration signal and a current signal collected from the condition monitoring system, respectively. The Dempster-Shafer (D-S) theory is then applied to fuse the probabilistic outputs of two SVMs to get the final fault diagnostic result. Experiments are conducted for a gearbox with different types of fault, where a gearbox vibration signal and a generator current signal are collected to prove the effectiveness of the proposed method. Results show that the proposed method is more robust and reliable than the traditional methods of using a single sensor or a single type of sensor for gearbox fault diagnosis.
High speed VCSEL-based links for use in data centers and HPC (2016)

This tutorial will cover the use and application of directly modulated Vertical Cavity Surface Emitting Lasers (VCSELs), high speed direct detection receivers and multi-mode fiber for data centers and High Performance Computing (HPC) applications. Topics will include packaging, advances in modulation performance to 71 Gb/s and 50 Gb/s high temperature operation to 90C, higher fiber bandwidth density using multi-core multimode fiber and Short Wavelength Division Multiplexing (SWDM) using extended window single fiber. Other topics will include the use of equalization to extend the bit rate and the use of CMOS to lower the link power consumption.
Missing Baryons and the Warm-Hot Intergalactic Medium (2008)

Stars and gas in galaxies, hot intracluster medium, and intergalactic photo-ionized gas make up at most half of the baryons that are expected to be present in the universe. The majority of baryons are still missing and are expected to be hidden in a web of warm-hot intergalactic medium. This matter was shock-heated during the collapse of density perturbations that led to the formation of the relaxed structures that we see today. Finding the missing baryons and thereby producing a complete inventory of possibly the only detectable component of the energy-mass budget of the universe is crucial to validate or invalidate our standard cosmological model.
Clinical and Serological Findings of COVID-19 Participants in the Region of Makkah, Saudi Arabia (2022)

Makkah in Saudi Arabia hosts the largest annual religious event in the world. Despite the many strict rules enacted, including Hajj cancellation, city lockdowns, and social distancing, the region has the second highest number of new COVID-19 cases in Saudi Arabia. Public health interventions that identify, isolate, and manage new cases could slow the infection rate. While RT-PCR is the current gold standard in SARS-CoV-2 identification, it yields false positive and negative results, which mandates the use of complementary serological tests. Here, we report the utility of serological assays during the acute phase of individuals with moderate and severe clinical manifestations of SARS-CoV-2 (COVID19). Fifty participants with positive RT-PCR results for SARS-CoV-2 were enrolled in this study. Following RT-PCR diagnosis, serum samples from the same participants were analyzed using in-house ELISA (IgM, IgA, and IgG) and microneutralization test (MNT) for the presence of antibodies. Of the 50 individuals analyzed, 43 (86%) showed a neutralizing antibody titer of ≥20. Univariate analysis with neutralizing antibodies as a dependent variable and the degree of disease severity and underlying medical conditions as fixed factors revealed that patients with no previous history of non-communicable diseases and moderate clinical manifestation had the strongest neutralizing antibody response "Mean: 561.11". Participants with severe symptoms and other underlying disorders, including deceased individuals, demonstrated the lowest neutralizing antibody response. Anti-spike protein antibody responses, as measured by ELISA, showed a statistically significant correlation with neutralizing antibodies. This reinforces the speculation that serological assays complement molecular testing for diagnostics; however, patients' previous medical history (anamnesis) should be considered in interpreting serological results.
Time Survey of Triage Emergency Department Patients during Rush and Non-Rush Periods (2007)

Study Objective: The aims of this study were to analysis the relationship between the various severity triage levels and time expenditure in an emergency department (ED). This involved the analysis of time expended on the different triage level patients during rush or non-rush periods. Materials and Methods: The medical records of 400 patients were collected from the ED at the Mackay Memorial Hospital and retrospectively reviewed. The subjects were divided into different stages based on their progress through the ED. Recorded data included triage assessment, the different times expended at the different stages of treatment in the ED including triage assessment, registration, doctor's attendance and laboratory data examination and the arrival/departure times ofr the patients. Results: When the study groups were compared, there were significant differences between triage levels 1 patients compared to triage level 2 and 3 patients (p＜0.05) for all treatment stage times other than triage/ registration and the wait for initial physician attendance. In addition, overall, triage/registration and waiting for attendance times did not differ between the rush and non-rush periods. However, Level 1 triage patients took longer for all other timings during rush periods compared to non-rush periods (p＜0.05). Furthermore, level 2 and 3 triage patients took longer for triage and registration during rush periods compared to non-rush periods (p＜0.05). Conclusion: Typically, triage level 1 patients are more complex and require a longer diagnostic times than either level 2 or level 3 patients. Although disease/injury severity determines treatment priority, no such discrimination is used in less severe cases. This study indicates that level 1 cases use up much more time than level 2 and 3 for both doctor and laboratory examinations, but there is no increase in the waiting time for doctors during rush periods. Triage level 2 or 3 patients seem to have similar times for most activities except registration whether the ED is busy or not. It can therefore be concluded that improving procedures or setting up a team specifically for patients who are severely injured and who arrive during a busy periods may be helpful and reduce the risk of any delay in treatment of these patients, which is very important to every ED physician.
MPPT Algorithms for Magnus Effect Wind Turbine Control System (2020)

In this paper, wind energy is considered as a promising trend for the development of alternative energy. The physical implementation of a wind generator based on the Magnus effect is explained, as well as its mathematical model. The relationship between the rotation speed of the blades of a wind generator, the rotation speed of the rotor of the generator and wind speed is considered. The influence of the parameters on the mechanical power coefficient is evaluated. Algorithms for tracking the maximum power point and the effect of mechanical power coefficient on the amount of generated power are considered. Changes in the mechanical power coefficient during mathematical modelling under various conditions are analyzed.
Enhancing blood compatibility of biodegradable polymers by introducing sulfobetaine (2011)

Novel biodegradable polycaprolactone containing N,N'-bis (2-hydroxyethyl) methylamine ammonium propane sulfonate (PCL-APS) was synthesized by ring-opening polymerization. The resulting polymers were characterized by nuclear magnetic resonance spectrum (NMR), Fourier transform infrared (FTIR) spectroscopy, gel permeation chromatograph (GPC), differential scanning calorimetry (DSC), and water contact angle (WCA). These measurements showed that the APS unit was introduced into polymers. The hydrolysis of PCL-APS was evaluated by soaking the polymer membranes in a pH = 3.20 acid solution. The rate of weight loss was increased with the content of APS increasing in polymer. The compatibility of polymers were evaluated by platelet adhesion, hemolytic test, and activated partial thromboplastic time (APTT) and prothrombin time (PT) experiments. Results showed that adhered platelets deceased after introducing sulfobetaine as compared to the control PCL, little hemolysis took place on PCL-APS, and APTT of PCL-APS polymers was prolonged than that of control PCL. Therefore, polycaprolactone containing sulfobetaine is a promising biodegradable polymer with good blood compatibility.
The Role of ARX in Human Pancreatic Endocrine Specification (2015)

The in vitro differentiation of human embryonic stem cells (hESCs) offers a model system to explore human development. Humans with mutations in the transcription factor Aristaless Related Homeobox (ARX) often suffer from the syndrome X-linked lissencephaly with ambiguous genitalia (XLAG), affecting many cell types including those of the pancreas. Indeed, XLAG pancreatic islets lack glucagon and pancreatic polypeptide-positive cells but retain somatostatin, insulin, and ghrelin-positive cells. To further examine the role of ARX in human pancreatic endocrine development, we utilized genomic editing in hESCs to generate deletions in ARX. ARX knockout hESCs retained pancreatic differentiation capacity and ARX knockout endocrine cells were biased toward somatostatin-positive cells (94% of endocrine cells) with reduced pancreatic polypeptide (rarely detected), glucagon (90% reduced) and insulin-positive (65% reduced) lineages. ARX knockout somatostatin-positive cells shared expression patterns with human fetal and adult δ-cells. Differentiated ARX knockout cells upregulated PAX4, NKX2.2, ISL1, HHEX, PCSK1, PCSK2 expression while downregulating PAX6 and IRX2. Re-expression of ARX in ARX knockout pancreatic progenitors reduced HHEX and increased PAX6 and insulin expression following differentiation. Taken together these data suggest that ARX plays a key role in pancreatic endocrine fate specification of pancreatic polypeptide, somatostatin, glucagon and insulin positive cells from hESCs.