gebhart/patrepeval huggingface dataset:
Purification, characterization and cDNA cloning of bovine brain diacylglycerol lipase (1988)

Conference Article| June 01 1988 Purification, characterization and cDNA cloning of bovine brain diacylglycerol lipase AKHLAO A. FAROOQUI; AKHLAO A. FAROOQUI *Department of Physiological Chemistry, University, Columbus, OH 43210, U.S.A. Search for other works by this author on: This Site PubMed Google Scholar SHIYUAN CHENG; SHIYUAN CHENG *Department of Physiological Chemistry, University, Columbus, OH 43210, U.S.A. Search for other works by this author on: This Site PubMed Google Scholar KOTTIL RAMMOHAN; KOTTIL RAMMOHAN †Department of Neurology, College of Medicine, University, Columbus, OH 43210, U.S.A. Search for other works by this author on: This Site PubMed Google Scholar PAPACHAN KOLATTUKUDY; PAPACHAN KOLATTUKUDY ‡Biotechnology Center, The Ohio State University, Columbus, OH 43210, U.S.A. Search for other works by this author on: This Site PubMed Google Scholar LLOYD A. HORROCKS LLOYD A. HORROCKS *Department of Physiological Chemistry, University, Columbus, OH 43210, U.S.A. Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1988) 16 (3): 293–294. https://doi.org/10.1042/bst0160293 Article history Received: October 20 1987 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation AKHLAO A. FAROOQUI, SHIYUAN CHENG, KOTTIL RAMMOHAN, PAPACHAN KOLATTUKUDY, LLOYD A. HORROCKS; Purification, characterization and cDNA cloning of bovine brain diacylglycerol lipase. Biochem Soc Trans 1 June 1988; 16 (3): 293–294. doi: https://doi.org/10.1042/bst0160293 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1988 Biochemical Society1988 Article PDF first page preview Close Modal You do not currently have access to this content.
Analysis of Transcription Factor mRNAs in Identified Oxytocin and Vasopressin Magnocellular Neurons Isolated by Laser Capture Microdissection (2013)

The oxytocin (Oxt) and vasopressin (Avp) magnocellular neurons (MCNs) in the hypothalamus are the only neuronal phenotypes that are present in the supraoptic nucleus (SON), and are characterized by their robust and selective expression of either the Oxt or Avp genes. In this paper, we take advantage of the differential expression of these neuropeptide genes to identify and isolate these two individual phenotypes from the rat SON by laser capture microdissection (LCM), and to analyze the differential expression of several of their transcription factor mRNAs by qRT-PCR. We identify these neuronal phenotypes by stereotaxically injecting recombinant Adeno-Associated Viral (rAAV) vectors which contain cell-type specific Oxt or Avp promoters that drive expression of EGFP selectively in either the Oxt or Avp MCNs into the SON. The fluorescent MCNs are then dissected by LCM using a novel Cap Road Map protocol described in this paper, and the purified MCNs are extracted for their RNAs. qRT-PCR of these RNAs show that some transcription factors (RORA and c-jun) are differentially expressed in the Oxt and Avp MCNs.
Pharmacological study of BRS, a new bicarbonated Ringer's solution, in haemorrhagic shock dogs (2005)

These results suggest that BRS is a suitable perioperative solution for metabolic acidosis and serum electrolyte balance among RS tested.
Solution-Phase Parallel Synthesis of a Multisubstituted Cyclic Imidate Library (2013)

The solution-phase parallel synthesis of a diverse 71-member library of multisubstituted cyclic imidates is described. The key intermediates, 3-iodomethylene-containing cyclic imidates, are readily prepared in good to excellent yields by the palladium/copper-catalyzed cross-coupling of various o-iodobenzamides and terminal alkynes, followed by electrophilic cyclization with I2. These cyclic imidates were further functionalized by palladium-catalyzed Suzuki-Miyaura, Sonogashira, carbonylative amidation, and Heck chemistry using sublibraries of commercially available building blocks.
A Counter-Intuitive Condition for the Wrap Reinforcement of Aluminum-Rigidized Tubes (2002)

An attractive and straightforward means to improve the deployment characteristics and the performance of aluminum-rigidized tubes is hoop reinforcement via chord (filament) wound onto the tube. This wrap, among other advantages, (a) may prevent the unduly domination of aluminum laminate plastification during rigidization by the hoop stresses and (b) may continue to stiffen the tube wall after rigidization for improved structural performance. While the advantages of the filament wrap during the rigidization are obvious and easily demonstrable, its contribution to the performance of the deployed strut are not well understood. One of the many details on which this contribution critically depends, the elasto-plastic interaction between the aluminum laminate wall and the reinforcing wrap, is in the focus of the present paper. In particular, it is shown via a simple model that this interaction plays a critical role in defining whether the wrap can directly contribute to the deployed performance at all. A counter-intuitive conclusion of the study is that an unduly high filament stiffness can effectively eliminate any direct reinforcing effect of the rigidized tube by the wrap if certain additional conditions apply. This work complements a paper by Lichodziejewski et al. which summarizes practical and experimental aspects of the technology 1 .
Investigation of Proviral Load in Individuals Infected with Human T-Lymphotropic Virus Type II (1995)

Human T-lymphotrophic virus type II (HTLV-II) has not yet been associated with any disease. Little is known about the proviral loads of HTLV-II in vivo and its relationship, if any, to lack of pathogenicity. We determined the HTLV-II proviral copy number in peripheral blood lymphocyte (PBL) samples from 49 HTLV-II-infected individuals, of whom 25 were coinfected with human immunodeficiency virus type 1 (HIV-1). The HTLV-II copy numbers were determined by polymerase chain reaction (PCR) amplification of end-point dilutions of PBL lysates, followed by hybridization to a 32P-labeled HTLV-II-specific probe. The proviral copy number for the 49 samples ranged from < 0.02 to 200 per 1000 PBLs; 6% had < 0.02, 16% had 0.02, 20% had 0.2, 18% had 2, 31% had 20, and 8% had 200 copies per 1000 PBLs. The distributions of HTLV-II copy numbers in the coinfected and singly infected subgroups were not significantly different (Wilcoxon rank sum, p = 0.24). In the coinfected subgroup, there was no significant correlation between the HTLV-II proviral load and the counts of CD4-positive lymphocytes or CD8-positive lymphocytes (Spearman Coefficient = 0.26, p = 0.20; = 0.091, p = 0.67, respectively). Our data demonstrate the presence of a wide range of viral loads in HTLV-II-infected individuals. The high viral loads (> or = 20 copies/1000 lymphocytes) detected in 39% of our samples suggest that the low pathogenicity of HTLV-II is not related to the presence of low viral loads in the infected subjects. Our data from the HIV-1 coinfected individuals show no apparent effect of HIV-1 on HTLV-II proviral loads.
Numerical Simulation of Excimer Laser Cleaning of Film and Particle Contaminants (2013)

Laser cleaning is a promising surface preparation technique for applications in high value manufacturing industries. However, understanding the effects of laser processing parameters on various types of contaminants and substrates, is vital to achieve the required cleaning efficacy and quality. In this paper, a two-dimensional transient numerical simulation was carried out to study the material ablation characteristics and substrate thermal effects in laser cleaning of aerospace alloys. Element birth and death method was employed to track the contaminant removal on the surface of the material. The result shows that contaminant ablation increases with laser power and number of pulses. The finite element method (FEM) model is capable enough to predict the optimum number of pulses and laser power required to remove various contaminants. Based on the simulation results, the mechanism of the excimer laser cleaning is proposed. Thus, the use of numerical simulation can be faster and cheaper method of establishing the optimum laser cleaning window and reducing the number of experimental tests.
Intakes of coffee, tea, milk, soda and juice and renal cell cancer in a pooled analysis of 13 prospective studies (2007)

Specific beverage intake may be associated with the risk of renal cell cancer through a diluting effect of carcinogens, alterations of hormone levels, or other changes in the renal tubular environment, but few prospective studies have examined these associations. We evaluated the associations between coffee, tea, milk, soda and fruit and vegetable juice intakes and renal cell cancer risk in a pooled analysis of 13 prospective studies (530,469 women and 244,483 men). Participants completed a validated food-frequency questionnaire at baseline. Using the primary data, the study-specific relative risks (RRs) were calculated and then pooled using a random effects model. A total of 1,478 incident renal cell cancer cases were identified during a follow-up of 7-20 years across studies. Coffee consumption was associated with a modestly lower risk of renal cell cancer (pooled multivariate RR for 3 or more 8 oz (237 ml) cups/day versus less than one 8 oz (237 ml) cup/day = 0.84; 95% CI = 0.67-1.05; p value, test for trend = 0.22). Tea consumption was also inversely associated with renal cell cancer risk (pooled multivariate RR for 1 or more 8 oz (237 ml) cups/day versus nondrinkers = 0.85; 95% CI = 0.71-1.02; pvalue, test for trend = 0.04). No clear associations were observed for milk, soda or juice. Our findings provide strong evidence that neither coffee nor tea consumption increases renal cell cancer risk. Instead, greater consumption of coffee and tea may be associated with a lower risk of renal cell cancer. (c) 2007 Wiley-Liss, Inc.
Small-area, high-radiance c.w. InGaAsP l.e.d.s emitting at 1.2 to 1.3 μm (1977)

Double-heterostructure InP/lnGaAsP/lnP high-radiance l.e.d.s have been fabricated by liquid-phase epitaxy on the &lt;IIIB&gt; face of commercially available InP substrates. The best small-area l.e.d.s had a useful external power efficiency of 1.5% and a 900 Å-wide emission spectrum centred at 1.23 μm. emitting ∼3 mW into the air at 100 mA and 2 V; essentially similar results were obtained with devices operating al 1.30 μm.
Échangeurs de chaleur - Définitions et architecture générale (1994)

Tous ces auteurs font partie du Groupement pour la Recherche sur les Échangeurs Thermiques (GRETh) L’échangeur d’énergie thermique est un des instruments clé du thermicien ou de l’énergéticien, que son but soit la fabrication d’un produit dont l’élaboration passe par un ensemble de cycles où varient
Estimating collection size with logistic regression (2007)

Collection size is an important feature to represent the content summaries of a collection, and plays a vital role in collection selection for distributed search. In uncooperative environments, collection size estimation algorithms are adopted to estimate the sizes of collections with their search interfaces. This paper proposes heterogeneous capture (HC) algorithm, in which the capture probabilities of documents are modeled with logistic regression. With heterogeneous capture probabilities, HC algorithm estimates collection size through conditional maximum likelihood. Experimental results on real web data show that our HC algorithm outperforms both multiple capture-recapture and capture history algorithms.
Parameterizing total storm conduction currents in the Community Earth System Model (2016)

Abstract Electrified clouds are known to play a major role in the Global Electric Circuit. These clouds produce upward currents which maintain the potential difference between Earth's surface and the upper atmosphere. In this study, model output from two simulations of the Community Earth System Model (CESM) are compared with conduction currents and other data derived from the Tropical Rainfall Measuring Mission (TRMM) satellite, including both the Lightning Imaging Sensor and Precipitation Radar. The intention is to determine CESM's skill at representing these microphysical and dynamical properties of clouds. Then, these cloud properties are used to develop a model parameterization to compute conduction currents from electrified clouds. Specifically, we evaluate the ability of global mean convective mass flux, ice water path, and convective precipitation to represent conduction current sources. Parameterizations using these variables yield derived global mean currents that agree well with the geographical patterns of TRMM currents. In addition, comparing the diurnal variations of modeled global mean current to the observed diurnal variations of electric potential gradient, root‐mean‐square (RMS) errors range between 6.5% and 8.1%, but the maximum occurs 4 to 6 h early in all three variables. Output currents derived from the model variables generally match well to the currents derived from TRMM, and the total global current estimates agree well with past studies. This suggests that cloud parameters are well suited for representing the global distribution and strength of currents in a global model framework.
Structure–Activity Studies on the Fluorescent Indicator in a Displacement Assay for the Screening of Small Molecules Binding to RNA (2012)

A series of xanthone and thioxanthone derivatives with aminoalkoxy substituents were synthesized as fluorescent indicators for a displacement assay in the study of small-molecule-RNA interactions. The RNA-binding properties of these molecules were investigated in terms of the improved binding selectivity to the loop region in the RNA secondary structure relative to 2,7-bis(2-aminoethoxy)xanthone (X2S) by fluorimetric titration and displacement assay. An 11-mer double-stranded RNA and a hairpin RNA mimicking the stem loop IIB of Rev response element (RRE) RNA of HIV-1 mRNA were used. The X2S derivatives with longer aminoalkyl substituents showed a higher affinity to the double-stranded RNA than the parent molecule. Introduction of a methyl group on the aminoethoxy moiety of X2S effectively modulated the selectivity to the RNA secondary structure. Methyl group substitution at the C1' position suppressed the binding to the loop regions. Substitution with two methyl groups on the amino nitrogen atom resulted in reducing the affinity to the double-stranded region by a factor of 40%. The effect of methyl substitution on the amino nitrogen atom was also observed for a thioxanthone derivative. Titration experiments, however, suggested that thioxanthone derivatives showed a more prominent tendency of multiple binding to RNA than xanthone derivatives. The selectivity index calculated from the affinity to the double-stranded and loop regions suggested that the N,N-dimethyl derivative of X2S would be suitable for the screening of small molecules binding to RRE.
A Trust and Reputation based Anti-SPIM Method (2008)

Instant Messaging (IM) service is a killer application in the Internet. Due to the problem of IM spam (SPIM), building an effective anti-spim method is an important research topic. At present, most of anti-spim solutions are based on email-spam prevention techniques, which are not directly applicable to anti-spim. We present a new anti-spim method SpimRank, which integrates trust and reputation mechanisms with black-list technique. SpimRank also tracks user's historical action to deal with spim attacks in nearly real time, which is applicable to IM environment.
Modulating Electrical Performances of In2O3 Nanofiber Channel Thin Film Transistors via Sr Doping (2019)

Abstract Although In 2 O 3 nanofibers (NFs) are considered as one of the fundamental building blocks for future electronics, the further development of these NFs devices is still seriously hindered by the large leakage current, low on/off current ratio ( I on / I off ), and large negative threshold voltage ( V TH ) due to the excess carriers existed in the NFs. A simple one‐step electrospinning process is employed here to effectively control the carrier concentration of In 2 O 3 NFs by selectively doping strontium (Sr) element to improve their electrical device performance. The optimal devices (3.6 mol% Sr doping concentration) can yield the high field‐effect mobility (μ fe ≈ 3.67 cm 2 V −1 s −1 ), superior I on / I off ratio (≈10 8 ), and operation in the energy‐efficient enhancement‐mode. High‐κ Al 2 O 3 thin films can also be employed as the gate dielectric to give the gate voltage greatly reduced by 10× (from 40 to 4 V) and the μ fe substantially increased by 4.8× (to 17.2 cm 2 V −1 s −1 ). The electrospun E‐mode Sr‐In 2 O 3 NF field‐effect transistors (NFFETs) can as well be integrated into full swing of inverters with excellent performances, further elucidating the significant advance of this electrospinning technique toward practical applications for future low‐cost, energy‐efficient, large‐scale, and high‐performance electronics.
An electrically and magnetically responsive nanocomposite of GdPO4·H2O/P3HT/PLGA with electrical stimulation for synergistically enhancing the proliferation and differentiation of pre-osteoblasts (2019)

The electric–magnetic responsive nanocomposite GdPO<sub>4</sub>·H<sub>2</sub>O/P3HT/PLGA could enhance MRI signals, and synergistically accelerate proliferation and osteogenic differentiation upon electrical stimulation.
Study of Energy Deposition and Activation for the LINAC4 Dump (2008)

This document provides estimates of energy deposition and activation for the dump of the future LINAC4 accelerator. Detailed maps of power density deposited in the dump are given, allowing to perform further thermo mechanical studies. Residual dose rates at a few cooling times for different irradiation scenarios have been calculated. Moreover, the air activation has been evaluated and doses to the reference population group and to a worker intervening in the cave at the shutdown have been predicted. Calculations were performed with the Monte Carlo particle transport and interaction code FLUKA.
Quality of Transmission and Protection Schemes in Hybrid WDM Optical Networks (2006)

Many investigations have been carried out in the field of path protection and restoration in WDM optical networks. Most of these studies neglect the impact of physical layer impairments on routing and wavelength assignment strategies, and more specifically on protection strategies. Actually, an optical signal undergoes throughout its route many transmission impairments. In the absence of 3R regenerators at intermediate nodes, transmission impairments are accumulated at the receivers side and translated in Bit Error Rate (BER). In this paper, we investigate a dedicated path protection scheme under physical layer constraints. Given a set of traffic demands and a network topology, our objective is to minimize the number of 3R regenerators required to ensure the quality of transmission (QoT) on both primary and backup paths. According to the adopted policy (1+1 or 1:1 ), we propose two protection classes. In the case of 1+1 protection, we assume that the same QoT is required on both primary and backup paths whilst in the case of 1:1 protection, we tolerate a higher BER on backup paths. QoT is evaluated in considering four physical layer impairments, namely chromatic dispersion, polarization mode dispersion, nonlinear phase shift and amplified spontaneous emission. In our numerical simulations, we consider two admissible BER: 10&#8722;9 for the primary paths and 10&#8722;6 for the backup paths.
Resiliency of the Multiscale Retinex Image Enhancement Algorithm (1998)

The multiscale retinex with color restoration (MSRCR) continues to prove itself in extensive testing to be a very versatile automatic image enhancement algorithm that simultaneously provides dynamic range compression, color constancy, and color rendition. However, issues remain with regard to the resiliency of the MSRCR to different image sources and arbitrary image manipulations which may have been applied prior to retinex processing. In this paper we define these areas of concern, provide experimental results, and, examine the effects of commonly occurring image manipulations on retinex performance. In virtually all cases the MSRCR is highly resilient to the effects of both the image-source variations and commonly encountered prior image-processing. Significant artifacts are primarily observed for the case of selective color channel clipping in large dark zones in an image. These issues are of concern in the processing of digital image archives and other applications where there is neither control over the image acquisition process, nor knowledge about any processing done on the data beforehand.
Effect of Applying Electromagnetic Force on Falling Behaviour of Molten Metal Film (1987)

In order to obtain a uniform and stable molten metal film, the shape control function induced by high frequency magnetic field is utilized.Firstly, the falling behaviour of liquid film shaped by a slit nozzle was observed in a water-model experiment by use of a high speed VTR. The falling liquid is classified into two regions. Namely, one is denoted as the film flow region appearing in the middle part of the falling liquid and the other as the channel flow region appearing in both sides of the film flow region. The width of the film flow region decreased continuously with increase in the falling distance. A mathematical model predicting the falling behaviour of the liquid film is developed on the basis of hydrodynamics and is verified by the water-model experiment.Then, the effect of magnetic field on the falling molten-metal film is studied by the mathematical model taking into account the magnetic pressure induced by magnetic field.