gebhart/patrepeval huggingface dataset:
Indicadores del estado nutricional de larvas de rodaballo Scophthalmus maximus (L., 1758) (1998)

Se han analizado diferentes indicadores del estado nutricional de larvas de rodaballo Scophthalmus maximus (L., 1758) alimentadas de hasta 53 días de edad y se han comparado con los de otras larvas sometidas a condiciones de inanición. Los indicadores estudiados fueron longitud, peso seco, condición relativa larvaria, diámetro del otolito, histología digestiva de las larvas, contenido en ácidos grasos, ácido ascórbico, RNA, DNA Y proteínas. Los procesos de inanición se llevaron a cabo a los 3, 9, 16, 23 Y 27 días de edad y los análisis de estas larvas fueron comparados con los de larvas alimentadas de las mismas edades. Durante las primeras 24 horas de inanición, las goticulas lipídicas en las células epiteliales desaparecen por completo del intestino. Después, la condición relativa disminuye aproximadamente el 5% por día y el diámetro relativo del otolito se incrementa en el 5% por día. Se producen también disminuciones en el peso seco, el contenido proteico, los niveles de ácidos grasos 18:1Ω-9, 20:5Ω-3 (EPA) y los de otros ácidos grasos altamente insaturados (Ω-3 HUFA), y en la relación RNA/DNA. Sin embargo, la mayoría de los indicadores investigados muestran una alta variación, incluso entre las distintas experiencias de cultivo realizadas, por lo que se concluye que las gotículas de lípidos en las células epiteliales del intestino, la condición relativa y el diámetro relativo del otolito son las únicas variables que pueden ser útiles para detectar un proceso de inanición en larvas de rodaballo.
Optical properties of a liquid crystal with small ordinary and extraordinary refractive indices and small optical anisotropy (2014)

Abstract Optical properties of a nematic liquid crystal with small refractive index and small birefringence were studied. The ordinary and extraordinary refractive indices and birefringence were measured as functions of temperature by using an Abbe refractometer and wedge nematic cells. From values of these indices the nematic orientational order parameter was calculated by using several methods and corresponding mathematical models. Kuczyński et al. method was found to be suitable for determining the order parameter also for materials featuring small ordinary refractive index, with unknown density.
SOS Regulation of the Type III Secretion System of EnteropathogenicEscherichia coli (2007)

Genomes of bacterial pathogens contain and coordinately regulate virulence-associated genes in order to cause disease. Enteropathogenic Escherichia coli (EPEC), a major cause of watery diarrhea in infants and a model gram-negative pathogen, expresses a type III secretion system (TTSS) that is encoded by the locus of enterocyte effacement (LEE) and is necessary for causing attaching and effacing intestinal lesions. Effector proteins encoded by the LEE and in cryptic prophage are injected into the host cell cytoplasm by the TTTS apparatus, ultimately leading to diarrhea. The LEE is comprised of multiple polycistronic operons, most of which are controlled by the global, positive regulator Ler. Here we demonstrated that the LEE2 and LEE3 operons also responded to SOS signaling and that this regulation was LexA dependent. As determined by a DNase I protection assay, purified LexA protein bound in vitro to a predicted SOS box located in the divergent, overlapping LEE2/LEE3 promoters. Expression of the lexA1 allele, encoding an uncleavable LexA protein in EPEC, resulted in reduced secretion, particularly in the absence of the Ler regulator. Finally, we obtained evidence that the cryptic phage-located nleA gene encoding an effector molecule is SOS regulated. Thus, we demonstrated, for the first time to our knowledge, that genes encoding components of a TTSS are regulated by the SOS response, and our data might explain how a subset of EPEC effector proteins, encoded in cryptic prophages, are coordinately regulated with the LEE-encoded TTSS necessary for their translocation into host cells.
Data compression using antidictionaries (2000)

We give a new text-compression scheme based on forbidden words ("antidictionary"). We prove that our algorithms attain the entropy for balanced binary sources. They run in linear time. Moreover, one of the main advantages of this approach is that it produces very fast decompressors. A second advantage is a synchronization property that is helpful to search compressed data and allows parallel compression. The techniques used in this paper are from information theory and finite automata.
Delirium etiology subtypes and their effect on six-month function and cognition in older emergency department patients (2018)

Delirium is heterogeneous and different etiologies may have different prognostic implications. Furthermore, the effect of these delirium etiologies on outcome may be dependent on the patient's pre-illness functional status and cognition.
Experimental investigation of the abnormal vibration of the electric locomotive (2016)

This paper presents the results of a detailed experimental investigation of the abnormal vibration of the electric locomotive. A locomotive suffered from serious vibration problem was chosen for the test and its normal operations kept unchanged during the test. The wheel out-of-roundness (OOR) and vibrations of key components including the axle box, the bogie frame and the car body were measured before and after wheel re-profiling. The measured OOR results indicate that the wheels exhibit the OOR with orders 12 to 22 before re-profiling, i.e. with the center wavelengths of 200-315 mm in 1/3 octave bands. The wheel polygonal wear cannot be absolutely removed by the wheel re-profiling. The 16th-19th order OOR becomes to be dominant after re-profiling. The vibration test results show that the axle box, the bogie frame and the car body vibrate with the same dominant frequency before re-profiling. The dominant frequency of the vibration is approximately equal to the passing frequency of a polygonal wheel. The vibrations are significantly reduced after re-profiling. The wheel polygonal wear is the root cause of the abnormal vibration.
Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism (2007)

Idiopathic hypogonadotropic hypogonadism (IHH) due to defects of gonadotropin-releasing hormone (GnRH) secretion and/or action is a developmental disorder of sexual maturation. To date, several single-gene defects have been implicated in the pathogenesis of IHH. However, significant inter- and intrafamilial variability and apparent incomplete penetrance in familial cases of IHH are difficult to reconcile with the model of a single-gene defect. We therefore hypothesized that mutations at different IHH loci interact in some families to modify their phenotypes. To address this issue, we studied 2 families, one with Kallmann syndrome (IHH and anosmia) and another with normosmic IHH, in which a single-gene defect had been identified: a heterozygous FGF receptor 1 (FGFR1) mutation in pedigree 1 and a compound heterozygous gonadotropin-releasing hormone receptor (GNRHR) mutation in pedigree 2, both of which varied markedly in expressivity within and across families. Further candidate gene screening revealed a second heterozygous deletion in the nasal embryonic LHRH factor (NELF) gene in pedigree 1 and an additional heterozygous FGFR1 mutation in pedigree 2 that accounted for the considerable phenotypic variability. Therefore, 2 different gene defects can synergize to produce a more severe phenotype in IHH families than either alone. This genetic model could account for some phenotypic heterogeneity seen in GnRH deficiency.
ChemInform Abstract: TRICOORDINATE HYPERVALENT SULFUR COMPOUNDS (1977)

Abstract Aus dem Imidazolthion (I) wird durch Bromierung (Brz, CHCIZ, 0°C) das Disulfid (II) erhalten, das bei weiterer Bromierung unter gleichen Bedingungen das stabile Sulfuran (IIIa) liefert (monoklin, P2, /C, Z=8).
Synchronization in chaotic systems (1990)

Certain subsystems of nonlinear, chaotic systems can be made to synchronize by linking them with common signals. The criterion for this is the sign of the sub-Lyapunov exponents. We apply these ideas to a real set of synchronizing chaotic circuits.
Evaluation of different DNA sampling techniques for the application of the real-time PCR method for the quantification of cyanobacteria in water (2006)

Application of quantitative genotype analysis in cyanobacteria from freeze-dried samples collected during recent and past sampling programmes.
Year-Long Trend in Glycated Hemoglobin Levels in Patients with Type 2 Diabetes during the COVID-19 Pandemic (2021)

It has been suggested that the coronavirus disease 2019 (COVID-19) pandemic has had a negative impact on glycemic control in patients with type 2 diabetes mellitus (T2DM). However, no study has examined yearly trends in glycated hemoglobin (HbA1c) levels after the start of the COVID-19 outbreak. Here, we performed a retrospective analysis of HbA1c concentrations during the early period of the COVID-19 outbreak (COVID-19 cohort) and then compared the yearly trend in the mean HbA1c level, along with fluctuations in HbA1c levels, with those during previous years (non-COVID-19 cohorts). We observed that the mean HbA1c level in patients with T2DM increased during the first 6 months of the COVID-19 outbreak. After 6 months, HbA1c levels in the COVID-19 cohort returned to levels seen in the non-COVID-19 cohorts. The data suggest that vulnerable patients with T2DM should be monitored closely during the early period of a pandemic to ensure they receive appropriate care.
Adobe Premiere Pro CS3 Classroom in a Book (2007)

Watch out, Final Cut Pro. For the first time in five years, Adobe Premiere Pro, Adobe's flagship digital video editing application, is once again available for both Macintosh and Windows users. This project-based book covers not just the basics of working with audio, creating transitions, and producing titles, but also all that's new in Premiere Pro: the ability to build Blu-ray Disc, DVD, and Flash projects with Adobe Encore CS3 (now included with Premiere Pro CS3); Adobe OnLocation CS3, which lets on-the-road users record footage directly to their computer disk--removing the need to capture video to tape later. Readers will enjoy learning to create slow-motion effects with Time Remapping, and will get up to speed on Premiere's new editing tools. What's more, users can compress their finished video for delivery to the latest handheld devices, such as mobile phones, iPods, PSPs, smartphones, and more. Best of all, the book's accompanying DVD includes real footage that you can practice on.
Novel technique for generating macrophage foam cells for in vitro reverse cholesterol transport studies (2013)

Generation of foam cells, an essential step for reverse cholesterol transport studies, uses the technique of receptor-dependent macrophage loading with radiolabeled acetylated LDL. In this study, we used the ability of a biologically relevant detergent molecule, lysophosphatidylcholine (lyso-PtdCho), to form mixed micelles with cholesterol or cholesteryl ester (CE) to generate macrophage foam cells. Fluorescent or radiolabeled cholesterol/lyso-PtdCho mixed micelles were prepared and incubated with RAW 264.7 or mouse peritoneal macrophages. Results showed that such micelles were quite stable at 4°C and retained the solubilized cholesterol during one month of storage. Macrophages incubated with cholesterol or CE (unlabeled, fluorescently labeled, or radiolabeled)/lyso-PtdCho mixed micelles accumulated CE as documented by microscopy, lipid staining, labeled oleate incorporation, and by TLC. Such foam cells unloaded cholesterol when incubated with HDL but not with oxidized HDL. We propose that stable cholesterol or CE/lyso-PtdCho micelles would offer advantages over existing methods.
Headache and Methemoglobinemia (2019)

The case highlights the need to broaden the formulated differential diagnosis of an acute onset severe holocranial headache and pay careful attention to other signs and symptoms that may provide hints on potential mechanism(s) for secondary headaches. We provide justification for the need to incorporate "Headache attributed to Methemoglobinemia" as a subtype under the section "Headache attributed to hypoxia and/or hypercapnia" of the International Classification of Headache Disorders to support clinical decision making.
Laser-Based In-Exhaust Gas Sensor for On-Road Vehicles (2022)

&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;A novel laser-absorption gas sensing apparaOn-vehicle Testing at VERtus capable of measuring NO directly within vehicle exhaust was developed and tested. The sensor design was enabled by key advances in the construction of optical probes that are sufficiently compact for deployment in real-world exhaust systems and can survive the harsh, high-temperature, and strongly vibrating environment typical of exhaust streams. Prototype test campaigns were conducted at high-temperature flow facilities intended to simulate exhaust gas conditions and within the exhaust of vehicles mounted on a chassis dynamometer. Results from these tests demonstrated that the sensor prototype is fundamentally free of cross-interference with competing species in the exhaust stream, can achieve a 1 ppmv NO detection limit, and can be operated across the full range of thermodynamic conditions expected for typical vehicle exhausts. These features address the key technological drawbacks associated with electrochemical NO&lt;sub&gt;x&lt;/sub&gt; sensors widely used in current aftertreatment systems while enabling an on-board diagnostic capable of determining NO&lt;sub&gt;x&lt;/sub&gt; output at the tailpipe at a level of accuracy comparable to laboratory-grade instrumentation. Broadly, this novel sensor provides high-quality emissions data needed to help vehicle manufacturers develop powertrains and aftertreatment systems that meet future, more stringent emissions regulations.&lt;/div&gt;&lt;/div&gt;
Electrostatic Potential Maps on Molecular Surfaces Using Least Squares Reconstruction (2023)

Biomolecular surface electrostatic potential maps (EPMs) are routinely used to infer biological function, binding sites, and qualitative guidance (and subsequent quantitative assessment) of the geometric and electrostatic properties of receptor-drug complexes. A major challenge in Poisson-Boltzmann (PB) modeling and generation of EPMs is accurately accounting for the dielectric discontinuity at the molecular surface and associated jump in normal electrostatic field. One option for accommodating such solutions is to develop a surface conforming grid such that no element or mesh edge intersects the molecular surface. Given the complex shapes of biomolecules, unstructured tetrahedral grids are usually necessary to develop such grids. Here an alternate approach is presented that first develops an adaptive Cartesian grid with no attempt to align it with the molecular surface. Next each mesh edge that intersects the surface is processed by identifying the intersection point and then using a least squares-based reconstruction (LSR) method to estimate the surface potentials and their gradients. The LSR incorporates the analytical surface matching constraints, satisfies the PBE locally, accounts for surface curvature, and is combined with the finite difference scheme used at off-surface points to solve the PB equation. This results in a global set of equations that solves the governing equations at all interior and exterior points, and couples then at the edge intersection points. The LSR is implemented in the adaptive Cartesian grid PB solver (from herein called CPB) and applied to a variety of biomolecular systems ranging from small to very large-scale (e.g., viruses) assemblies to compute electrostatic energies, forces, and high-quality estimates of the surface EPM. Using LSR within CPB allows additional memory savings and proper visualization and rationalization of electrostatic complementarity/recognition features of protein-drug and nucleic acid-ligand complexes, with the latter requiring inclusion of nonlinear screening effects. In addition to detailing the LSR method, the article provides several recommendations for producing accurate, reliable, and reproducible biomolecular EPMs. The importance of performing grid convergence tests to ensure converged predictions is emphasized along with the need to properly account for nonlinear effects in highly charged systems and provide sufficient details of the biomolecular geometry, grid size, environmental conditions, and choice of contour levels to facilitate comparison against other EPM generation software.
Enhanced Beat Wave Saturation Amplitude in an Ionizing Plasma (1987)

The excitation of a plasma wave by two laser beams, whose frequency difference is near the plasma frequency, is studied in a plasma with a density that is slowly increasing with time due to ongoing ionization as appropriate for experiments done in laser breakdown plasmas. Numerical integration of the relativistic equation for the evolution of the wave amplitude reveals that for a rate of increase of the plasma density of approximately 1017 cm-3/ns at a laser intensity I = 1014 W/cm2, the wave amplitude can rise considerably above the relativistic saturation limit of Rosenbluth and Liu which was obtained for a plasma of constant density. This increase in plasma density compensates the reduction in plasma frequency caused by the relativistic electron mass increase when the wave amplitude is large. The frequency and phase excursions of the plasma wave are reduced for an optimum time increasing density. We find that moderate damping can stabilize both the amplitude and the phase of the plasma wave with respect to the pump.
S75 | CyanoMetDB | Comprehensive database of secondary metabolites from cyanobacteria (2021)

This is the collection associated with list S75 CyanoMetDB Comprehensive database of secondary metabolites from cyanobacteria on the NORMAN Suspect List Exchange. https://www.norman-network.com/nds/SLE/ CyanoMetDB is a comprehensive database of secondary metabolites from cyanobacteria manually curated from primary references described in Jones et al (2021), DOI: 10.1016/j.watres.2021.117017 (preprint DOI: 10.1101/2020.04.16.038703) <em><strong>Contents: </strong></em> Original database: CyanoMetDB_WR_Feb2021.csv and CyanoMetDB_WR_Feb2021.xlsx <br> Reference information (only) expanding Ref entries in database: CyanoMetDB_References_v02_WR_Feb2021.csv and CyanoMetDB_References_v02_WR_Feb2021.xlsx <br> MetFrag local CSV file (original database abridged and reformatted for use in MetFrag): CyanoMetDB_MetFrag_Feb2021.csv <br> Additional files for matching InChIKeys (rapid suspect flagging): CyanoMetDB_v02_InChIKeys.txt<br> DTXSIDs for CompTox LIST use only: CyanoMetDB_v02_DTXSIDs.txt Changes in versions are documented in the changelog file: CyanoMetDB_WR_changelog.txt <br> NOTE: several "names" fields contain special characters, please use CSV name column entries with caution (refer to "*_CSV columns for plain text forms). Original entries with special characters are in the respective XLSX files.
Dicamba Absorption and Translocation as Influenced by Formulation and Surfactant (1985)

Absorption and translocation of 14 C-dicamba (3,6-dichloro- o -anisic acid) in seven salt formulations were determined 60 h after application to leaves of soybean [ Glycine max (L.) Merr. ‘Williams’] grown in nutrient solution. The dimethylamine (DMA) formulation was consistently absorbed and retained in the plant in amounts equal to or greater (46% of recovered 14 C) than other formulations (which averaged 19% of recovered 14 C) when applied without surfactant. Absorption and subsequent retention of the DMA formulation in the plant was least affected of all formulations by the addition of a surfactant. With a surfactant, absorption of the DMA, monoethanolamine (MEA), and inorganic salt formulations was similar (&gt;75% of recovered 14 C). Addition of seven surfactants to the K-salt of dicamba increased both the amount of 14 C absorbed by 35 to 56% and the amount recovered in the plant. All surfactants except one enhanced absorption of the K-salt of dicamba to a similar degree. Dicamba exhibited predominantly symplastic translocation with the majority of 14 C being recovered in the new second trifoliolate leaves and nutrient solution. As much as 66% of the radioactivity absorbed through the leaves was exuded by roots into the nutrient solution 60 h after leaf treatment.
[Occurrence of AmpC-positive Klebsiella pneumoniae strains in patients with haematological malignancies]. (2008)

All AmpC-positive isolates were false-susceptible to at least one of the tested third-generation cephalosporins. In one patient, clinically apparent infection caused by this strain was documented. The reported results suggest the possibility of occurrence of AmpC-beta-lactamases in K. pneumoniae strains with clinical significance.
Long-Term Protection from Myocardial Ischemic Events in a Randomized Trial of Brief Integrin ??3 Blockade with Percutaneous Coronary Intervention (1998)

TOPOL, ERIC J.; FERGUSON, JAMES J.; WEISMAN, HARLAN F.; TCHENG, JAMES E.; ELLIS, STEPHEN G.; KLEIMAN, NEAL S.; IVANHOE, RUSSELL J.; WANG, ANN L.; MILLER, DAVID P.; ANDERSON, KEAVEN M.; CALIFF, ROBERT M. FOR THE EPIC INVESTIGATOR GROUP Author Information
Layers of interacting dynamic networks: Motivation and theory (2013)

We propose a framework for modeling two interacting network dynamics, that is promising as a representation of infrastructural dynamics modulated by underlying environmental uncertainties. Specifically, we propose using a stochastic automaton network known as the influence model to capture the evolution of discrete-valued environmental uncertainty statuses. The environmental-uncertainty process is viewed as driving a linear network model that captures an infrastructural dynamics of interest. This two-layer hybrid network model is shown to permit low-computation statistical (moment) analysis of meshed environmental and infrastructure dynamics.
Nascent zeolite frameworks grown from amorphous gels – identification and prospects for crystal engineering (2010)

Abstract From the standpoint of designing microporous frameworks with desired pore diameter and dimensionality, and, especially, the optimization of crystal habit, the crystal engineering of new zeolites must be based on concepts/procedures different from those appropriate for the design of organic crystals. This is because the structure building units proposed by Barrer and co-workers are probably not instrumental for framework construction, thus eliminating the important ‘synthon’ approach used for the construction of innovative organic solids. With some variant of the Flanigen model for crystal growth via one SiO 2 unit at a time, the best approach to zeolite crytal growth engineering appears to occur indirectly via structure directing agents that can also be modified to influence the emergent crystal habit. Prospects for identifying frameworks emerging from synthesis gels are also discussed in this review, revealing that the use of radial distribution functions is less informative than for the analysis of silicate glasses.
Supplementary Table S1 from Prevalence, Long-term Development, and Predictors of Psychosocial Consequences of False-Positive Mammography among Women Attending Population-Based Screening (2023)

&lt;p&gt;Summary of the Swedish Consequences of Screening - Breast Cancer (COS-BC) questionnaire.&lt;/p&gt;