gebhart/patrepeval huggingface dataset:
How bromate oscillators are controlled (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHow bromate oscillators are controlledPeter Ruoff, Margit Varga, and Endre KorosCite this: Acc. Chem. Res. 1988, 21, 9, 326–332Publication Date (Print):September 1, 1988Publication History Published online1 May 2002Published inissue 1 September 1988https://pubs.acs.org/doi/10.1021/ar00153a002https://doi.org/10.1021/ar00153a002research-articleACS PublicationsRequest reuse permissionsArticle Views198Altmetric-Citations29LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Vinylidene Homologation of Boronic Esters and its Application to the Synthesis of the Proposed Structure of Machillene (2019)

Alkenyl boronic esters are important reagents in organic synthesis. Herein, we report that these valuable products can be accessed by the homologation of boronic esters with lithiated epoxysilanes. Aliphatic and electron-rich aromatic boronic esters provided vinylidene boronic esters in moderate to high yields, while electron-deficient aromatic and vinyl boronic esters were found to give the corresponding vinyl silane products. Through DFT calculations, this divergence in mechanistic pathway has been rationalized by considering the stabilization of negative charge in the C-Si and C-B bond breaking transition states. This vinylidene homologation was used in a short six-step stereoselective synthesis of the proposed structure of machillene, however, synthetic and reported data were found to be inconsistent.
Influence of Renal Impairment on the Pharmacokinetics of Afatinib: An Open-Label, Single-Dose Study (2016)

Moderate-to-severe renal impairment had a minor influence on the pharmacokinetics of afatinib that was within the observed inter-individual variability, suggesting that afatinib treatment can be considered in this patient population. Registered at ClinicalTrials.gov as NCT02096718.
Laser-driven ion acceleration using isolated mass-limited spheres (2010)

We report on our experiments on laser-driven ion acceleration using fully isolated mass-limited spheres with a diameter down to 8 μm for the first time. Two-dimensional (2D) particle-in-cell (PIC) and hydro-code simulations were used to show that the pre-plasma at both the front and rear sides of the target strongly affect the efficiency of the ion acceleration. The mechanism of the plasma flow around mass-limited targets has not yet been identified for laser-driven ion acceleration. Our models indicate that this effect is the cause of the observed limitation to the ion-beam energy in both previous experiments and in our own.
A chemical model for phosphomutases: a dissociative thiophosphoryl transfer reaction proceeding with retention of configuration (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA chemical model for phosphomutases: a dissociative thiophosphoryl transfer reaction proceeding with retention of configurationPaul M. Cullis and Rajinder MisraCite this: J. Am. Chem. Soc. 1991, 113, 25, 9679–9680Publication Date (Print):December 1, 1991Publication History Published online1 May 2002Published inissue 1 December 1991https://pubs.acs.org/doi/10.1021/ja00025a047https://doi.org/10.1021/ja00025a047research-articleACS PublicationsRequest reuse permissionsArticle Views36Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Effectiveness of Digital Breast Tomosynthesis Compared With Digital Mammography (2016)

Digital breast tomosynthesis screening outcomes are sustainable, with significant recall reduction, increasing cancer cases per recalled patients, and a decline in interval cancers.
Supplementary Figure Legend from Parathyroid Hormone–Related Protein Drives a CD11b<sup>+</sup>Gr1<sup>+</sup> Cell–Mediated Positive Feedback Loop to Support Prostate Cancer Growth (2023)

&lt;p&gt;PDF file - 76K&lt;/p&gt;
Experimental Results of Rician K-Factor and Co-Polarization Ratio of 60 GHz Wireless Channel in an Underground Mine Gallery (2015)

In this work, experimental results of the Rician K-factor and the co-polarization ratio (CPR) are obtained and discussed from measurements conducted at 40 m CANMET underground mine gallery with Horn and Omnidirectional antennas with Horizontal (H) and Vertical (V) polarizations. These results suggest that the VV polarization offers a larger number of multipath components than the HH polarization, a correlation coefficient of about 0.86 between them, and an average CPR of about 6 dB. Furthermore, the average value of the Rician K-factor shows little or no difference between the HH and VV polarizations. The average CPR value remains around 6 dB. A correlation coefficient of multipath total power between HH and VV polarization is also found to be 0.8649.
Congenital amusics use a secondary pitch mechanism to identify lexical tones (2017)

Amusia is a pitch perception disorder associated with deficits in processing and production of both musical and lexical tones, which previous reports have suggested may be constrained to fine-grained pitch judgements. In the present study speakers of tone-languages, in which lexical tones are used to convey meaning, identified words present in chimera stimuli containing conflicting pitch-cues in the temporal fine-structure and temporal envelope, and which therefore conveyed two distinct utterances. Amusics were found to be more likely than controls to judge the word according to the envelope pitch-cues. This demonstrates that amusia is not associated with fine-grained pitch judgements alone, and is consistent with there being two distinct pitch mechanisms and with amusics having an atypical reliance on a secondary mechanism based upon envelope cues.
Role of the mitral valve in left ventricular assist device pathophysiology (2022)

Functional mitral regurgitation (MR) in the setting of heart failure results from progressive dilatation of the left ventricle (LV) and mitral annulus. This leads to leaflet tethering with posterior displacement. Contrary to common assumptions, MR often does not resolve with LVAD decompression of the LV alone. The negative impact of significant (moderate-severe) mitral regurgitation in the LVAD setting is becoming better recognized in terms of its harmful effect on right heart function, pulmonary vascular resistance and hospital readmissions. However, controversies remain regarding the threshold for intervention and management. At present, there are no consensus indications for the repair of significant mitral regurgitation at the time of LVAD implantation due to the conflicting data regarding potential adverse effects of MR on clinical outcomes. In this review, we summarize the current understanding of MR pathophysiology in patients supported with LVAD and potential future management strategies.
Devices and monitoring during neonatal ECMO: su rvey results (1990)

A survey of active ECMO centres regarding neonatal ECMO equipment and personnel was obtained by telephone interview in late summer 1989. Forty-seven of the centres in the USA listed in the Ann Arbor ELSO (Extracorporeal Life Support Organization) Registry at the time ( greater than 90%) were contacted and all participated. Nearly all use a roller pump, while less than 5% use a centrifugal pump. All programmes use a SciMed membrane oxygenator and 90% a SciMed heat exchanger. Heat exchanger water sources include the Gaymar T-pump (42%), Seabrook (25%) and Cincinnati Sub-Zero (23%) units. Eighty-seven per cent use a bladder box servo-regulated to the roller pump; these are most often custom-made (69%) but 13% of programmes use a commercially available (Seabrook) bladder box. Ten per cent use a pressure-regulated roller pump rather than a conventional (displacement) bladder box to detect decreases in venous return. Nearly 80% monitor circuit line pressures between the pump and patient. Seventeen per cent use an air bubble detector on the arterial side of the circuit. Only 10% use an arterial bubble trap and 6% an arterial line filter. Seventy-five per cent do not monitor gas line pressures into the membrane lung, but one-third do use a gas line pop-off valve to prevent elevated gas phase pressures. Seventy per cent reported use of continuous in-line measurement of mixed venous oxygen saturation; no programme reported any blood chemistries being monitored in line.(ABSTRACT TRUNCATED AT 250 WORDS)
Ethics and Privacy Implications of Using the Internet and Social Media to Recruit Participants for Health Research: A Privacy-by-Design Framework for Online Recruitment (2017)

Researchers, REBs, ethicists, students, and potential study participants are often unaware of the privacy risks of social media research recruitment and there is no official guidance. Our PbD framework for online health research recruitment is a resource for these wide audiences.
A Methodology for Accounting for Uneven Ride Height in Soft Suspensions with Large Lateral Separation (2009)

&lt;div class="htmlview paragraph"&gt;This study pertains to motion control algorithms using statistical calculations based on relative displacement measurements, in particular where the rattle space is strictly limited by fixed end-stops and a load leveling system that allows for roll to go undetected by the sensors. One such application is the cab suspension of semi trucks that use widely-spaced springs and dampers and a load leveling system that is placed between the suspensions, near the center line of the cab. In such systems it is possible for the suspension on the two sides of the vehicle to settle at different ride heights due to uneven loading or the crown of the road. This paper will compare the use of two moving average signals (one positive and one negative) to the use of one root mean square (RMS) signal, all calculated based on the relative displacement measurement. It will illustrate the advantage of using two moving average relative displacement signals for motion control application with concrete examples. If the nominal ride height is assumed to be the zero point of the relative displacement measurements, the two moving average signals are computed for both the positive and the negative portion independently. The highest value of the two is used for motion control. The results show that a clear distinction can be noticed between a high amplitude displacement signal and a low amplitude displacement with a high DC offset, two scenarios that may not be distinguishable using RMS calculations. The results suggest that the method that involves two moving averages is a better alternative to using one RMS calculation.&lt;/div&gt;
In vitro susceptibility of Plasmodium falciparum Welch field isolates to infusions prepared from Artemisia annua L. cultivated in the Brazilian Amazon (2012)

Artemisinin is the active antimalarial compound obtained from the leaves of Artemisia annua L. Artemisinin, and its semi-synthetic derivatives, are the main drugs used to treat multi-drug-resistant Plasmodium falciparum (one of the human malaria parasite species). The in vitro susceptibility of P. falciparum K1 and 3d7 strains and field isolates from the state of Amazonas, Brazil, to A. annua infusions (5 g dry leaves in 1 L of boiling water) and the drug standards chloroquine, quinine and artemisinin were evaluated. The A. annua used was cultivated in three Amazon ecosystems (várzea, terra preta de índio and terra firme) and in the city of Paulínia, state of São Paulo, Brazil. Artemisinin levels in the A. annua leaves used were 0.90-1.13% (m/m). The concentration of artemisinin in the infusions was 40-46 mg/L. Field P. falciparum isolates were resistant to chloroquine and sensitive to quinine and artemisinin. The average 50% inhibition concentration values for A. annua infusions against field isolates were 0.11-0.14 μL/mL (these infusions exhibited artemisinin concentrations of 4.7-5.6 ng/mL) and were active in vitro against P. falciparum due to their artemisinin concentration. No synergistic effect was observed for artemisinin in the infusions.
Development of high-temperature separation techniques for the chemical composition analysis of ethylene - methyl methacrylate block copolymers (2005)

Abstract Ethylene - methyl methacrylate block copolymers are semicrystalline polymers that dissolve in organic solvents only at high temperatures. Accordingly, microstructure analysis by solution methods must be conducted at temperatures above 130°C. For the analysis of block copolymers of different compositions several analytical techniques were used, including high-temperature size-exclusion chromatography (SEC), hyphenated SEC-FTIR, and CRYSTAF (crystallisation analysis fractionation). While SEC with refractive index detection indicated a certain multimodality of the samples, SEC coupled with FTIR revealed that the samples were chemically inhomogeneous and may contain homo- and copolymer fractions. The presence of polyethylene and poly(methyl methacrylate) homopolymers in the copolymer samples was confirmed by CRYSTAF analysis, when the total concentration as well as the carbonyl group distribution were monitored separately. Chromatographic separation of the different sample components was achieved when liquid chromatography at critical conditions (LC-CC) was used. For the first time, true high-temperature LC-CC methods were developed operating at a column temperature of 140°C. As the stationary phase, silica gel was used. Suitable mobile phases were binary mixtures of 1,2,4-trichlorobenzene or 1,2- dichlorobenzene with cyclohexanone. Using LC-CC, the samples were separated into the copolymer and the homopolymer fractions.
A G.711 Embedded Wideband Speech Coding for VoIP Conferences (2006)

This paper proposes a wideband speech coder in which a G.711 bitstream is embedded. This coder has an advantage over conventional coders in that it has a high interoperability with existing terminals so costly transcoding involving decoding and re-encoding can be avoided. We also propose a partial mixing method that effectively reduces the mixing complexity in multiple-point remote conferences. To reduce the complexity, we take advantage of the scalable structure of the bitstream and mix only the lower band of the signal. For the higher band, the main speaker location is selected among remote locations and is redistributed with the mixed lower-band signal. By subjective evaluations, we show that the speech quality can be maintained even when the speech signals are partially mixed.
Silicon Optical Phased Array with High-Efficiency Beam Formation over 180 Degree Field of View (2018)

Chip-scale optical phased arrays could enable compact beam steering and LIDAR for autonomous vehicles, precision robotics, and free-space optical communications. Because these applications demand wide angle beam steering as well as high optical power in the output beam, a natural design choice would be to space the array emitters at a half-wavelength pitch, as is common in radiofrequency phased arrays. Optical phased arrays, however, unlike RF phased arrays, have been limited by the tradeoff between field of view (i.e. angle steering) and beamforming efficiency (i.e. optical power in the output beam). This tradeoff exists because optical phased arrays rely on waveguides as emitters, which suffer from strong crosstalk when placed in close proximity relative to their mode size. Here we overcome these limitations and demonstrate a platform for optical phased arrays with 180° field of view, where more than 72 percent of the power is carried in a single diffraction-limited beam even when steered up to 60° off-axis. Our platform leverages high index-contrast, dispersion-engineered waveguides spaced one half-wavelength apart without incurring crosstalk.
ATS-PD: An Adaptive Testing System for Psychological Disorders (2016)

The clinical assessment of mental disorders can be a time-consuming and error-prone procedure, consisting of a sequence of diagnostic hypothesis formulation and testing aimed at restricting the set of plausible diagnoses for the patient. In this article, we propose a novel computerized system for the adaptive testing of psychological disorders. The proposed system combines a mathematical representation of psychological disorders, known as the "formal psychological assessment," with an algorithm designed for the adaptive assessment of an individual's knowledge. The assessment algorithm is extended and adapted to the new application domain. Testing the system on a real sample of 4,324 healthy individuals, screened for obsessive-compulsive disorder, we demonstrate the system's ability to support clinical testing, both by identifying the correct critical areas for each individual and by reducing the number of posed questions with respect to a standard written questionnaire.
Influence of acute stress on the triiodothyronine (T3) and serotonin content of rat's immune cells (2005)

Stress caused by 48 h food and water deprivation provoked significant changes in T3 and serotonin content of lymphocytes. The concentration of these hormones decreased in the last hour of stress. However, 48 h later there was no difference between the hormone content of immune cells of stressed and control animals. Since in earlier experiments three weeks after exposed to stress a significant difference between the control and stressed animals was found, this means that an imprinting-like phenomenon happened with consequences manifested later. The most sensitive cells to acute stress are lymphocytes, however the imprinting influences all types of of the immune cells.
Coatings Based on Brassylic Acid (An Erucic Acid Derivative) (1990)

Erucic acid, HOOC(CH2)11CH=CH(CH2)7CH3, can be economically obtained from rapeseed ana crambe abyssinica oils and is potentially a major source of industrial materials. It can be ozonized to brassylic acid, HOOC(CH2)11COOH, which is known to impart flexibility and moisture resistance to nylons. Here preliminary results of a study of brassylic acid as a monomer for polyester resin/melamine resin coatings are described. It is demonstrated that brassylic acid imparts good flexibility to such coatings. It is also shown that brassylic acid is polymorphic.
Endogenous and exogenous electric fields as modifiers of brain activity: rational design of noninvasive brain stimulation with transcranial alternating current stimulation (2020)

Synchronized neuronal activity in the cortex generates weak electric fields that are routinely measured in humans and animal models by electroencephalography and local field potential recordings. Traditionally, these endogenous electric fields have been considered to be an epiphenomenon of brain activity. Recent work has demonstrated that active cortical networks are surprisingly susceptible to weak perturbations of the membrane voltage of a large number of neurons by electric fields. Simultaneously, noninvasive brain stimulation with weak, exogenous electric fields (transcranial current stimulation, TCS) has undergone a renaissance due to the broad scope of its possible applications in modulating brain activity for cognitive enhancement and treatment of brain disorders. This review aims to interface the recent developments in the study of both endogenous and exogenous electric fields, with a particular focus on rhythmic stimulation for the modulation of cortical oscillations. The main goal is to provide a starting point for the use of rational design for the development of novel mechanism-based TCS therapeutics based on transcranial alternating current stimulation, for the treatment of psychiatric illnesses.
Accurate and rapid novel genetic diagnosis for detection of sentinel lymph node metastasis in breast cancer patients (2012)

Our results showed that the detection of CK19 and CEA mRNA using the TRC test is, an accurate and rapid method for detection of SLN metastasis and can be applied as an intraoperative molecular diagnosis in breast cancer patients.
Tracking Motion-Blurred Targets in Video (2006)

Many emerging applications require tracking targets in video. Most existing visual tracking methods do not work well when the target is motion-blurred (especially due to fast motion), because the imperfectness of the target's appearances invalidates the image matching model (or the measurement model) in tracking. This paper presents a novel method to track motion-blurred targets by taking advantage of the blurs without performing image restoration. Unlike the global blur induced by camera motion, this paper is concerned with the local blurs that are due to target's motion. This is a challenging task because the blurs need to be identified blindly. The proposed method addresses this difficulty by integrating signal processing and statistical learning techniques. The estimated blurs are used to reduce the search range by providing strong motion predictions and to localize the best match accurately by modifying the measurement models.
Firmware development and testing of the ATLAS Pixel Detector / IBL ROD card (2015)

The ATLAS Experiment is reworking and upgrading systems during the current LHC&#13;\nshut down. In particular, the Pixel detector has inserted an additional inner layer called the Insertable&#13;\nB-Layer (IBL). The Readout-Driver card (ROD), the Back-of-Crate card (BOC), and the&#13;\nS-Link together form the essential frontend data path of the IBL’s off-detector DAQ system. The&#13;\nstrategy for IBL ROD firmware development was three-fold: keeping as much of the Pixel ROD&#13;\ndatapath firmware logic as possible, employing a complete new scheme of steering and calibration&#13;\nfirmware, and designing the overall system to prepare for a future unified code version integrating&#13;\nIBL and Pixel layers. Essential features such as data formatting, frontend-specific error handling,&#13;\nand calibration are added to the ROD data path. An IBL DAQ test bench using a realistic front-end&#13;\nchip model was created to serve as an initial framework for full offline electronic system simulation.&#13;\nIn this document, major firmware achievements concerning the IBL ROD data path implementation,&#13;\ntest on the test bench and ROD prototypes, will be reported. Recent Pixel collaboration efforts&#13;\nfocus on finalizing hardware and firmware tests for the IBL. The plan is to approach a complete&#13;\nIBL DAQ hardware-software installation by the end of 2014.