gebhart/patrepeval huggingface dataset:
Fatal Meningitis from Shiga Toxin–Producing Escherichia coli in 2 Full-Term Neonates, France (2023)

We report fatal meningitis in 2 neonates in France caused by Shiga toxin 1-producing Escherichia coli. Virulence factors capsular K1 antigen and salmochelin were present in both strains, potentially representing a new hybrid pathotype. Clinicians should remain aware of emerging pathotypes and design therapeutic strategies for neonatal E. coli infections.
Microstructural characterization of propylene–butene‐1 copolymer using temperature rising elution fractionation (1998)

Propylene–butene-1 copolymer (PBC) prepared with a titanium catalyst system was fractionated by temperature rising elution fractionation (TREF) over a temperature range of 5–80°C. PBC was shown to have a wide composition distribution ranging between 12–47 mol % of butene-1. Most of the fractions showed nearly the same crystallinity regardless of the butene-1 content. However, the solubility of the crystalline parts, which turned out to be the driving force for the fractionation, varied over the butene-1 content. Evidence that PBC shows isomorphism was obtained by the analysis of fractionated polymers, using 13C nuclear magnetic resonance spectrometry, X-ray diffraction, differential scanning calorimetry, and gel permeation chromatography. © 1998 John Wiley & Sons, Inc. J Appl Polym Sci 68: 1493–1501, 1998
Cyclic GMP modulates depletion-activated Ca2+ entry in pancreatic acinar cells (1993)

In the pancreatic acinar cell, hormonal stimulation causes a rise in the intracellular free Ca2+ concentration by activating the inositol 1,4,5-trisphosphate-mediated release of Ca2+ from intracellular stores (Berridge, M. J., and Irvine, R. F. (1989) Nature 341, 197-205). The released Ca2+ is, for the most part, extruded from the cell, necessitating a mechanism for Ca2+ entry and reloading of intracellular Ca2+ stores (Putney, J. W., Jr. (1990) Cell Calcium 11, 611-624; Rink, T. J. (1990) FEBS Lett. 268, 381-385). However, neither the mechanism of depletion-activated Ca2+ entry nor the signal that activates it is known. We report here that a sustained inward current of depletion-activated Ca2+ entry can be measured in pancreatic acinar cells using patch-clamp recording methods. Furthermore, the current can be blocked by an inhibitor of guanylyl cyclase, can be reactivated by 8-bromo-cGMP after inhibition, and can be activated in the absence of Ca2+ depletion by perfusing the cell with cGMP, but not cAMP. Intracellular perfusion with 1,3,4,5-inositol tetrakisphosphate did not activate an inward current, whereas perfusion with 2,4,5-inositol trisphosphate did activate an inward current. We conclude that cGMP may be an intracellular messenger that regulates depletion-activated Ca2+ entry.
Enantiomerically pure copper(I) and zinc(II) complexes of a novel C3-symmetric polypyrazole ligand (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEnantiomerically pure copper(I) and zinc(II) complexes of a novel C3-symmetric polypyrazole ligandChristopher J. Tokar, Peter B. Kettler, and William B. TolmanCite this: Organometallics 1992, 11, 8, 2737–2739Publication Date (Print):August 1, 1992Publication History Published online1 May 2002Published inissue 1 August 1992https://pubs.acs.org/doi/10.1021/om00044a001https://doi.org/10.1021/om00044a001research-articleACS PublicationsRequest reuse permissionsArticle Views365Altmetric-Citations56LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
The Depression Anxiety Stress Scale 8-Items Expresses Robust Psychometric Properties as an Ideal Shorter Version of the Depression Anxiety Stress Scale 21 Among Healthy Respondents From Three Continents (2022)

To examine the cultural limitations and implications in the applicability of the Depression Anxiety Stress Scale 8-items (DASS-8)-a shortened version of the DASS-21 recently introduced in an Arab sample-this study evaluated its psychometric properties, including measurement invariance, among healthy subjects from the United States, Australia, and Ghana. Confirmatory factor analysis revealed good fit of the DASS-8 relative to a 12-item version (DASS-12). Both the DASS-8 and the DASS-12 were invariant at all levels across genders, employment status, and students vs. non-students. The DASS-8/DASS-12 also expressed invariance at the configural and metric levels across all countries, albeit scalar invariance was not maintained due to misspecification of the factor loadings in the Ghanian sample. Mann-Whitney U test revealed significantly lower levels of mental symptomatology on the DASS measures among Ghanian students than in English-speaking respondents (both students and non-students). The DASS-8 expressed excellent internal consistency (coefficient alpha = 0.89), good convergent validity-noted by high values of item-total correlations (<i>r</i> = 0.87 to 0.88), good predictive validity-indicated by significantly strong correlation with the DASS-21 and its subscales (<i>r</i> = 0.95 to 0.80), and adequate discriminant validity-indicated by heterotrait-monotrait ratio of correlations <0.85. The DASS-8 correlated with the Internet Gaming Disorder-9, the Adult attention-deficit/hyperactivity disorder Self-Report Scale, and the Individualism and Collectivism Scale/Culture Orientation Scale at the same level as the DASS-21 and the DASS-12, denoting its adequate criterion validity. The DASS-8 can be used as a brief alternative to the DASS-21 to screen for mental symptomatology in English-speaking and African cultures. However, the same scores on the DASS-8 and the DASS-12 may not always indicate the same level of symptom severity in subjects from different countries. Further inter-cultural evaluations of the DASS-8 are needed.
Exploiting points-to maps for de-/serialization code generation (2013)

Serialization code generators for C++ have restrictions on the implementation of dynamic arrays and void/function pointers. If the target program is not implemented with these restrictions, developers have to manually change the source code to facilitate serialization code generation. Unfortunately, such changes hamper the benefits of code generation, and they are not localized. This paper presents the de-/serialization code generator Ser++ that does not restrict the implementation of these pointer types and, hence, eliminates the need to adapt the source code for serialization code generation.
Mechanochemical Preparation of Materials with Enhanced Characteristics for Lithium Batteries (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
Norepinephrine-Induced DNA Damage in Ovarian Cancer Cells (2020)

Multiple studies have shown that psychological distress in epithelial ovarian cancer (EOC) patients is associated with worse quality of life and poor treatment adherence. This may influence chemotherapy response and prognosis. Moreover, although stress hormones can reduce cisplatin efficacy in EOC treatment, their effect on the integrity of DNA remains poorly understood. In this study, we investigated whether norepinephrine and epinephrine can induce DNA damage and modulate cisplatin-induced DNA damage in three EOC cell lines. Our data show that norepinephrine and epinephrine exposure led to increased nuclear γ-H2AX foci formation in EOC cells, a marker of double-strand DNA breaks. We further characterized norepinephrine-induced DNA damage by subjecting EOC cells to alkaline and neutral comet assays. Norepinephrine exposure caused DNA double-strand breaks, but not single-strand breaks. Interestingly, pre-treatment with propranolol abrogated norepinephrine-induced DNA damage indicating that its effects may be mediated by β-adrenergic receptors. Lastly, we determined the effects of norepinephrine on cisplatin-induced DNA damage. Our data suggest that norepinephrine reduced cisplatin-induced DNA damage in EOC cells and that this effect may be mediated independently of β-adrenergic receptors. Taken together, these results suggest that stress hormones can affect DNA integrity and modulate cisplatin resistance in EOC cells.
Comparative Phenotypic and Genotypic Analysis of Edwardsiella Isolates from Different Hosts and Geographic Origins, with Emphasis on Isolates Formerly Classified as E. tarda, and Evaluation of Diagnostic Methods (2017)

<i>Edwardsiella</i> spp. are responsible for significant losses in important wild and cultured fish species worldwide. Recent phylogenomic investigations have determined that bacteria historically classified as <i>Edwardsiella tarda</i> actually represent three genetically distinct yet phenotypically ambiguous taxa with various degrees of pathogenicity in different hosts. Previous recognition of these taxa was hampered by the lack of a distinguishing phenotypic character. Commercial test panel configurations are relatively constant over time, and as new species are defined, appropriate discriminatory tests may not be present in current test panel arrangements. While phenobiochemical tests fail to discriminate between these taxa, data presented here revealed discriminatory peaks for each <i>Edwardsiella</i> species using matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) methodology, suggesting that MALDI-TOF can offer rapid, reliable identification in line with current systematic classifications. Furthermore, a multiplex PCR assay was validated for rapid molecular differentiation of the <i>Edwardsiella</i> spp. affecting fish. Moreover, the limitations of relying on partial 16S rRNA for discrimination of <i>Edwardsiella</i> spp. and advantages of employing alternative single-copy genes <i>gyrB</i> and <i>sodB</i> for molecular identification and classification of <i>Edwardsiella</i> were demonstrated. Last, <i>sodB</i> sequencing confirmed that isolates previously defined as typical motile fish-pathogenic <i>E. tarda</i> are synonymous with <i>Edwardsiella piscicida</i>, while atypical nonmotile fish-pathogenic <i>E. tarda</i> isolates are equivalent to <i>Edwardsiella anguillarum</i> Fish-nonpathogenic <i>E. tarda</i> isolates are consistent with <i>E. tarda</i> as it is currently defined. These analyses help deconvolute the scientific literature regarding these organisms and provide baseline information to better facilitate proper taxonomic assignment and minimize erroneous identifications of <i>Edwardsiella</i> isolates in clinical and research settings.
Refinement of the Superstructure of C-Type Gallium Tris(metaphosphate), Ga(PO3)3 (1998)

Single crystals of Ga(PO3)3 were grown in polyphosphoric acid melts by heating a mixture of Ga2O3 and H3PO4 (350 °C, 7 d). The compound belongs to the series of metaphosphates MIII(PO3)3 forming the C-type structure (monclinic, Cc, Z = 12, a = 13.0058(21), b = 18.915(3), c = 9.3105(15) Å, β = 126.900(11), 5348 independent reflections (I > 0); 354 variables; 39 atoms in asymetric unit; R1 = 0.048, wR2 = 0.1034). The structure is characterized by a superstructure with tripled monoclinic b-axis. Three crystallographically independent GaIIIO6 octahedra (d¯(Ga–O) = 1.950 Å) are linked by 1∞(PO3)– chains. Verfeinerung der Überstruktur von C-Typ Gallium-tris(metaphosphat) Einkristalle von Ga(PO3)3 wurden in Polyphosphorsäureschmelzen aus Ga2O3 und H3PO4 gezüchtet (620 K, 7 d). Die Verbindung gehört zu einer Serie von Metaphosphaten MIII(PO3)3, welche den sogenannten C-Strukturtyp (z. B.: C–Al(PO3)3) ausbilden. Charakteristisches Strukturmerkmal ist eine Überstruktur mit Verdreifachung der monoklinen b-Achse. Drei kristallographisch unabhängige GaIIIO6 Oktaeder (d¯(Ga–O) = 1.950 Å) werden durch 1∞(PO3)– verknüpft.
A new instrument for endoscopic release of the ulnar nerve in the cubital tunnel-a cadaveric investigation (2002)

Ulnar nerve entrapment within the cubital tunnel is a common clinical condition. Traditionally, nerve releases have been performed utilizing a long incision on the medial side of the elbow leaving a long scar, usually with some damage to the cutaneous nerves around the elbow and associated morbidity, plus, on the average, a three-to-four day stay in the hospital, With endoscopic techniques, improved results should be possible with one small incision on the postero-medial side of the arm and a much more aesthetic result. This should be possible as an out-patient surgical procedure with decreased overall morbidity. Early mobilization after endoscopic surgery could also aid in an earlier return to work, resulting in a substantial reduction in health care costs. Safe endoscopic release of the ulnar nerve in the cubital tunnel at the elbow with a single 1.5 centimeter incision is possible thus eliminating many problems associated with the commonly used open release procedure. The newly developed technique with associated instrumentation for this surgical procedure was proven to be feasible under the in vitro conditions of this investigation.
The Use of Electrolyte Additives to Improve the High Temperature Resilience of Li-Ion Cells (2008)

As part of our continuing efforts to develop advanced electrolytes to improve the performance of lithium-ion cells, especially over wide temperature ranges, we have investigated a number of electrolyte additives, which were incorporated into multi-component electrolyte formulations with the intent of improveing the high temperature resilience. In the present work, we have investigated two Lewis base electrolyte additives developed at URI (1), namely dimethyl acetamide (DMAC) and N-methyl pyrrolidinone (NMP), which have been compared with other previously reported additives (i.e., vinylene carbonate, VC, and vinyl ethylene carbonate, VEC). These Lewis base stabilizing agents have been found to reversibly bind with PF5, preventing LiPF6 and carbonate solvents from undergoing decomposition at high temperature. These additives have been incorporated into a previously developed electrolyte consisting of LiPF6 dissolved in a ternary mixture of carbonates (2). It was determined that cells containing the electrolytes with the additives far outperformed the baseline solution with respect to the extent of capacity retention observed when subjected to high temperatures, with DMAc and VC yielding the best results
Risk factor analysis of kyphotic malalignment after cervical intramedullary tumor resection in adults (2017)

OBJECTIVE A number of studies have reported that surgery for cervical intramedullary tumors via the posterior approach can result in postoperative sagittal malalignment of the cervical spine; however, the risk factors remain unclear. The purpose of this study was to investigate the changes in cervical spinal alignment after surgery for cervical intramedullary tumors in adults and to elucidate the risk factors for cervical spinal sagittal misalignment. METHODS Data for the period from April 2001 to December 2011 for all adults who had undergone surgery for cervical intramedullary spinal cord tumors at a single institution were retrospectively analyzed to determine the postoperative changes in cervical spine alignment. Patients younger than 20 years of age and those who required postoperative radiotherapy were excluded from the study. Patients were divided into 2 groups according to tumor location: upper tumor (U) group, in which the central region of the tumor was above the C-5 level; and lower tumor (L) group, in which the central region of the tumor was at or below the C-5 level. Changes in alignment of the cervical spine were measured on plain lateral radiographs. Data on atrophy of the deep extensor muscles (DEMs), tumor location, detachment of the DEMs from the C-2 spinous process, the C2-7 angle before surgery, patient age at surgery, tumor histology, patient sex, tumor size, and number of laminae affected were reviewed for each patient, and the correlation of each of these factors with cervical spinal malalignment was evaluated using statistical analysis. RESULTS The 54 adults eligible for analysis had a mean age of 49.1 years. Ependymoma was the most common cervical intramedullary tumor (63.0%) in this series. In the tumor location U group, the kyphotic angle of the C2-7 spinal segments increased after surgery (-5.8° ± 2.8°). In contrast, in the L group, the C2-7 lordotic angle increased after surgery (6.4° ± 2.6°). In the univariate analysis, atrophy of the DEMs, detachment of the DEMs from the C-2 spinous process, and an upper cervical location of the tumor were identified as factors significantly correlated with the development of cervical spinal kyphosis after surgery. Multiple linear regression analysis revealed the following as risk factors for kyphotic change of the cervical spine after surgery: 1) atrophy of the DEMs after surgery (β = -0.54, p < 0.01), and 2) detachment of the DEMs from the C-2 spinous process (β = -0.37, p < 0.01). CONCLUSIONS Atrophy of the DEMs after surgery and detachment of the DEMs from the C-2 spinous process are directly related to the risk of cervical spinal kyphosis after surgery for cervical intramedullary tumors in adults. Therefore, preservation of the DEMs, especially those attached to the C-2 spinous process, is important for the prevention of kyphotic malalignment of the cervical spine after surgery for intramedullary tumors.
Antioxidant Grain Passivation for Air‐Stable Tin‐Based Perovskite Solar Cells (2018)

Tin-based perovskites with excellent optoelectronic properties and suitable band gaps are promising candidates for the preparation of efficient lead-free perovskite solar cells (PSCs). However, it is challenging to prepare highly stable and efficient tin-based PSCs because Sn<sup>2+</sup> in perovskites can be easily oxidized to Sn<sup>4+</sup> upon air exposure. Here we report the fabrication of air-stable FASnI<sub>3</sub> solar cells by introducing hydroxybenzene sulfonic acid or its salt as an antioxidant additive into the perovskite precursor solution along with excess SnCl<sub>2</sub> . The interaction between the sulfonate group and the Sn<sup>2+</sup> ion enables the in situ encapsulation of the perovskite grains with a SnCl<sub>2</sub> -additive complex layer, which results in greatly enhanced oxidation stability of the perovskite film. The corresponding PSCs are able to maintain 80 % of the efficiency over 500 h upon air exposure without encapsulation, which is over ten times longer than the best result reported previously. Our results suggest a possible strategy for the future design of efficient and stable tin-based PSCs.
Medical Plant and Human Health (2012)

1.1 Primary healthcare and traditional medicine Primary Health Care (PHC) is the key to the development of a national health policy based on practical, scientifically sound and socially acceptable methods and technology made universally acceptable to individuals and families in the community and through their full participation and at a cost that the community and the country can afford, in order to maintain, at every stage of their development, in the spirit of self-reliance and self determination. It is the first level of contact for the individual, family and the community within the national health care system, bringing health care as close as possible to where people live and work and thus constitutes the first element of a continuing health care process (WHO, 1978a). A health system, based on primary health care was adopted as the means of achieving the goal of health for all. Most developing countries of the world, for which the scheme was designed, have failed to seriously implement it up till this moment. Traditional Medicine is defined by the World Health Organization (WHO, 1978a) as the sum total of knowledge or practices whether explicable or inexplicable, used in diagnosing, preventing or eliminating a physical, mental or social disease which may rely exclusively on past experience or observations handed down from generation to generation, verbally or in writing. It also comprises therapeutic practices that have been in existence often for hundreds of years before the development of modern scientific medicine and are still in use today without any documented evidence of adverse effects. The explicable form of Traditional Medicine can be described as the simplified, scientific and the direct application of plant, animal or mineral materials for healing purposes and which can be investigated, rationalized and explained scientifically.
Privatization and Share Supply in Emerging Markets (2004)

Abstract The chapter considers domestic politics and share supply on emerging market stock exchanges. It argues that since the 1980s, states have created new exchanges not as vehicles to raise capital, but to reserve a role for local capital as it disengages from active management of the firm. Thus the state and the market do not act in opposition to each other; rather, the state creates a local market to allow its citizens access to ownership of local firms despite the fact that control of many of these firms lies overseas. The operative goal of the sale is thus corporate control, combined with revenue, and not just revenue alone. Structures respond to a myriad of domestic political concerns.
Supplementary material : Cost-effectiveness analysis of strategies using new immunological diagnostic tests of latent tuberculosis infection before TNF-blockers therapy (2018)

La Presse Medicale - In Press.Proof corrected by the author Available online since samedi 24 fevrier 2018
Electrochemical Applications of Silica-Based Organic−Inorganic Hybrid Materials (2001)

A comprehensive overview is presented on the implication of silica-based organic−inorganic hybrid materials in electrochemical science. It involves composite materials of both class I (weak bonds between the organic and inorganic components) and class II (strong chemical bonds). Starting with a description of the common designs of electrodes modified with these hybrids, the review then reports their applications in the various fields of electrochemistry, illustrating the diversity of the organically modified silicates used for this purpose. The mild chemical conditions allowed by the sol−gel process provide very versatile access to these electrochemical devices. They have found many applications in electroanalysis, including preconcentration associated with voltammetric detection, permselective coatings, electrochemical sensors, electrocatalysis, and detectors for chromatography. They were also applied as redox and conducting polymers, as solid polymer electrolytes for batteries, for the design of spectroelectrochemical and electro-chemiluminescence devices, and in the field of electrochemical biosensors.