gebhart/patrepeval huggingface dataset:
The (DD)E Complex Is Maintained by a Composite Fibrin Polymerization Site (1994)

The (DD)E complex is the major cross-linked fibrin degradation fragment. Structural components required for maintenance of the (DD)E complex were examined in order to better understand clot structure and the contribution of specific polypeptide chain segments in the process of polymerization. First, the (DD)E complex was reversibly dissociated by peptides derived from the alpha-chain NH2-terminus of fibrin having a minimal sequence of GPR (alpha 17-19). In addition, the complex was partially dissociated by peptide beta 40-54, while beta 50-55 and peptides derived from the fibrin beta-chain NH2-terminus had no effect. Second, monoclonal antibody (mAb) 1B6, specific for the alpha-chain NH2-terminus of fibrin, reacted rapidly with fragment E1, but did not recognize the corresponding epitope on the (DD)E complex. On the other hand, mAb 59D8, specific for GHRPL at the beta-chain NH2-terminus of fibrin, reacted with the (DD)E complex in a dose-dependent manner. Third, the (DD)E complex was irreversibly dissociated by proteolytic cleavage of fragment E1 by either thrombin, which removed GPR from the alpha-chain NH2-terminus, or Crotalus atrox protease III, which released beta 15-42. It has been concluded that fragment E1 contains a composite polymerization site consisting at least of residues alpha 17-19 and beta 20-49, which together maintain the (DD)E complex. These results illustrate that the complex is kept together by complementary binding sites which form a nucleus of linear fibrin polymerization sites. The (DD)E complex can thus be considered as a soluble model of fibrin clot.(ABSTRACT TRUNCATED AT 250 WORDS)
Integrating Models of Personality and Emotions into Lifelike Characters (1999)

. A growing number of research projects in academia and industry have recently started to develop lifelike agents as a new metaphor for highly personalised human-machine communication. A strong argument in favour of using such characters in the interface is the fact that they make humancomputer interaction more enjoyable and allow for communication styles common in human-human dialogue. Our earlier work in this area has concentrated on the development of animated presenters that show, explain, and verbally comment textual and graphical output on a window-based interface. Even though first empirical studies have been very encouraging and revealed a strong affective impact of our Personas [23], they also suggest that simply embodying an interface agent is insufficient. To come across as believable, an agent needs to incorporate a deeper model of personality and emotions, and in particular directly connect these two concepts. Introduction The German Research Centre for Artif...
Selectivities of .pi.- and .sigma.-succinimidyl radicals in substitution and addition reactions. Response to Walling, El-Taliawi and Zhao (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSelectivities of .pi.- and .sigma.-succinimidyl radicals in substitution and addition reactions. Response to Walling, El-Taliawi and ZhaoP. S. Skell, R. L. Tlumak, and S. SeshadriCite this: J. Am. Chem. Soc. 1983, 105, 15, 5125–5131Publication Date (Print):July 1, 1983Publication History Published online1 May 2002Published inissue 1 July 1983https://pubs.acs.org/doi/10.1021/ja00353a045https://doi.org/10.1021/ja00353a045research-articleACS PublicationsRequest reuse permissionsArticle Views439Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Magnetic resonance imaging of the coronary arteries (1999)

Magnetic resonance imaging of coronary arteries will visualize, besides the arteries, the myocardium, blood in the cavities and cardiac veins. This will hamper the application of projectional visualization techniques such as those used in conventional coronary angiography. Volume rendering, a different visualization technique, can be used to create a three-dimensional impression of a magnetic resonance data set on a two-dimensional surface. In this article, we will review the volume-rendering technique and anatomy of the coronary arteries and veins in the obtained images. Also we will discuss the relation between arteries and veins and the possible sites of confusion.
Measurements of the statistics of excess noise in separate absorption, grading and multiplication (SAGM) avalanche photodiodes (1984)

Measurements of the statistical distributions of excess noise as a function of avalanche gain and incident optical power are reported for SAGM avalanche photodiodes. The observed distributions are not Gaussian, but exhibit a ‘high-side’ tail which has consequences for the performance of these APDs in optical receivers.
Patient-specific changes in aortic hemodynamics is associated with thrombotic risk after fenestrated endovascular aneurysm repair with large diameter endografts (2022)

Patient-specific CFD simulation of fEVAR in juxtarenal aortic aneurysms demonstrated significant endograft diameter-dependent differences in aortic hemodynamics. A postoperative reduction in TAWSS and an increased RT correlated with future thrombotic events after large-diameter endograft implantation. Patient-specific simulation of hemodynamics provides a novel method for thrombotic risk stratification after fEVAR.
OP07.06: Mid‐trimester uterine and iliac artery Doppler in the prediction of placental insufficiency in chronic hypertensive women (2006)

To test the hypothesis that, in women with chronic hypertension before pregnancy, mid-trimester combined uterine and iliac Doppler artery is better than uterine artery alone in predicting the occurrence of pre-eclampsia or small-for-gestational-age (SGA) babies. Prospective study of 126 women with chronic hypertension who undergo color flow/pulsed Doppler imaging of both uterine and iliac arteries during the 20–24 weeks anomaly scan. Receiver operator characteristic (ROC) curves were created for uterine arteries notching, mean uterine and iliac arteries resistance index (RI) and pulsatility index (PI) individually or in combination. Comparison between area under ROC curves were made using Mann-Whitney U-tests. Thirty eight (30%) women developed pre-eclampsia and forty-two (33%) had SGA babies. For pre-eclampsia, areas under ROC curves were significantly higher using a ratio of mean uterine and iliac arteries RI than using mean uterine RI or notches or both (0.83 CI 95% [0.76–0.89] vs 0.62 CI 95% [0.56–0.69]; 0.67 CI 95% [0.58–0.75] and 0.68 CI 95% [0.59–0.76]; p < 0.01). For SGA babies, areas under ROC curves were also higher (0.84 CI 95% [0.76–0.92] vs 0.72 CI 95% [0.66–0.79]; 0.75 CI 95% [0.67–0.82] and 0.74 CI 95% [0.65–0.81]) in comparison to uterine artery parameter, however the difference did not reach statistical significance. Pre-eclampsia screening in chronic hypertensive patients using a combination of uterine and iliac artery Doppler is better than uterine artery Doppler alone. This may be due to reduced vascular compliance and increased impedance in women with chronic hypertension.
[Inflammation of the uterine corpus: endometritis]. (1990)

In industrialised countries endometritis is a problem which represents an increasing risk to personal health and to society. In almost all cases the inflammatory process which affects the uterine mucosa forms part of a more generalised infection which involves the entire internal genital system (PID). The most important problem associated with pelvic phlogosis is increased sterility, a greater number of ectopic pregnancies and chronic pelvic pain. In order to treat the symptoms of genito-pelvic infection, an early diagnosis and adequate medical therapy are indispensable. In this event it may be possible to prevent invalidating effects on fertility and chronic pelvic pain.
Microwave resonators with internal structure (2002)

Abstract If it is possible to divide a resonator in such a way that its specific modal electromagnetic fields are not disturbed, the resonant frequency of such a mode should change very little. On the other hand, the frequencies of other modes should change significantly. Hence, by using this approach, the spurious characteristics of the resonator can be controlled. Also, this division can be used as a means of improving the Q characteristic and the temperature behavior. In addition, it is possible to form a resonator by collecting many small particles. This is a concept for artificial media. By selection of particles and their assembly configuration, various resonant characteristics should become possible. In this paper, a method for improving the resonator characteristics by the above two dual methods is proposed. © 2002 Wiley Periodicals, Inc. Electron Comm Jpn Pt 2, 85(12): 38–48, 2002; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/ecjb.10058
Subwavelength microscope that uses frequency scanning for image reconstruction (2008)

A new principle of subwavelength imaging based on frequency scanning is considered. It is shown that it is possible to reconstruct the spatial profile of an external field exciting an array (or coupled arrays) of subwavelength-sized resonant particles with a frequency scan over the whole band of resonating array modes. During the scan it is enough to measure and store the values of the near field at one or at most two points. After the scan the distribution of the near field can be reconstructed with simple post-processing. The proposed near-field microscope has no moving parts.
Instrumentation for the Omnibus experiment in home energy conservation (1975)

In the Omnibus Experiment, residential energy consumption is being studied in thirty-two townhouses located at Twin Rivers, N.J. A report is given which enumerates the variables being monitored in the Omnibus study and presents the technical details of the instrumentation system used for measurement and data collection. Calibration for the instrumentation is discussed. A numerical example indicates how to convert raw field data into physical units. (GRA)
Reversed-Potential Halogen-Quenched Counters (1956)

First Page
Nanosecond-scale spectral diffusion in the single photon emission of a GaN quantum dot (2017)

Autocorrelation measurements are used to reveal the spectral diffusion time scale in the single photon emission of a GaN interface fluctuation quantum dot. Typical characteristic diffusion times of such QDs are revealed to be of nanosecond order. The excitation power dependence of the diffusion rate is also investigated, whereby an increase in the diffusion rate with increasing excitation power is observed. This result provides information on experimental conditions that will be required for the generation of indistinguishable photons.
Connectionist training of non-linear hidden Markov models for speech recognition (1991)

Neural networks and hidden Markov models (HMMs) are compared. It is shown that the conventional HMMs are equivalent to linear recurrent networks (LRNs) with time varying weights. Inspired by the nonlinear nature of nodes in the neural networks, nonlinearity is introduced into the HMMs. Accordingly, a connectionist training approach is proposed to train such nonlinear HMMs. The training is discriminative when the objective function is defined as the mutual information between the observed event and the Markov model. The introduction of nonlinearity allows one to view the HMMs in a broader perspective. For instance, the normalizing of forward probability can be interpreted as a kind of nonlinearity in a nonlinear HMM. The proposed training algorithm has been tested on a speaker-dependent isolated digit recognition problem; this test demonstrated that the discriminative power of the HMMs can be enhanced.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Chemical Nickel-Iron Films (1966)

Ferromagnetic films, useful for computer applications, have been deposited from a modified Brenner bath by chemical reduction using hypophosphite. The deposits contain about 25% iron, 1–0.5% phosphorus, small amounts of oxygen, carbon, etc. The balance is nickel. The films are well suited for memory applications because of their high creeping threshold and their fast coherent rotational switching. The effects of certain plating parameters on the properties, in particular on the magnetic properties, are discussed.
Development and validation of a CO2 gas cooler moving-boundary model. (2018)

This paper presents the development of a CO2 gas cooler model using the moving-boundary method. The model aims to separate the gas cooler into two regions: supercritical gas and supercritical liquid by means of the CoolProp thermophysical property library (Bell et al., 2014). The model uses the latest correlations for refrigerant and air-side heat transfer coefficients and pressure drops. The experimental results from Ge and Cropper (2009) are used for model validation. A total of at 36 operating conditions have been reported. The model predicted the gas cooler heating capacity within an MAE of ±4.7% and refrigerant side outlet temperature within ±3 K. The present moving-boundary model also showed an improved agreement compared to the segment-by-segment model proposed by Ge and Cropper (2009).
Mitos y construcción del imaginario nacional cotidiano (2003)

In Chile "la frontera" or border corresponded roughly to the Araucania, an area where the Mapuche Indians lived as well as settlers from the central zone and Europe. RESUMENLos grandes mitos fundadores de la nación los forjó la burguesía agraria del valle central en el recrudecimiento de su poder frente al pueblo que estaba al sur de la frontera.Entre ellos está el de la otredad del país, su carácter diferente respecto de los demás países latinoamericanos, la homogeneidad que diseñó un país blanco y reducido a la zona central, el carácter de cultura europea de nuestra identidad.El texto muestra las contradicciones de estas propuestas y agrega a la pluralidad del país el perfil del retornado así como se aproxima al mecanismo cultural que resulta del favor: el pituto.
Exploration of Methane Mitigation Efficacy Using &lt;i&gt;Asparagopsis&lt;/i&gt;-Derived Bioactives Stabilized in Edible Oil Compared to Freeze-Dried &lt;i&gt;Asparagopsis in Vitro&lt;/i&gt; (2022)

Asparagopsis oil products are of interest due to the stabilizing effects of the Asparagopsis-derived antimethanogenic bioactive compound bromoform (CHBr3). The objective of this in vitro series is to characterize antimethanogenic efficacy of freeze-dried Asparagopsis (FD-Asp) and Asparagopsis oil (Asp-Oil) and compare relative antimethanogenic response over time at multiple levels of CHBr3 delivery. Relative methane (CH4) emissions (mL/g) are based on in vitro apparent feed digested dry matter (IVDDM) after 24, 48, and 72 h of fermentation. CHBr3 contained in FD-Asp was included at 95, 191, and 286 mg/kg, and CHBr3 contained in Asp-Oil was included at 78, 117, and 175 mg/kg, to produce the Low, Mid, and High inclusions, respectively. Low FD-Asp had no significant impact on CH4 emissions, Mid FD-Asp demonstrated 91%, 44%, and 37% reductions, and the High FD-Asp demonstrated complete inhibition of CH4, after 24, 48, and 72 h of fermentation, respectively. Comparatively, Low Asp-Oil demonstrated a 46%, 28%, and 18% CH4 reduction, Mid Asp-Oil resulted in 99%, 92%, and 73% reductions, and the High Asp-Oil demonstrated complete inhibition of CH4 after 24, 48, and 72 h of fermentation, respectively. IVDDM and total volatile fatty acid (tVFA) production were not changed by the inclusion of FD-Asp and Asp-Oil. The results from this study show that Asparagopsis is not only a compelling CH4 mitigating feed supplement but is also able to be delivered in edible oil forms which will strengthen its applicability to on-farm use. This study is promising for the utility of Asp-Oil, and in vivo trials are essential to demonstrate the extent of efficacy of Asp-Oil in ruminant animals because FD-Asp has consistently demonstrated greater antimethanogenic efficacy in vivo compared to in vitro.
RHIC CHALLENGES FOR LOW ENERGY OPERATIONS (2007)

There is significant interest in RHIC heavy ion collisions at {radical}s =5-50 GeV/u, motivated by a search for the QCD phase transition critical point. The lowest energies are well below the nominal RHIC gold injection {radical}s = 19.6 GeV/u. There are several challenges that face RHIC operations in this regime, including longitudinal acceptance, magnet field quality, lattice control, and luminosity monitoring. We report on the status of work to address these challenges, including results from beam tests of low energy RHIC operations with protons and gold.
Loss of heterozygosity analysis in primary mammary tumors and lung metastases of MMTV-MTAg and MMTV-neu transgenic mice. (1997)

Loss of heterozygosity (LOH) analysis has been used in many types of human cancer to localize putative tumor suppressor genes important in carcinogenesis. However, this approach has only recently been applied to transgenic mouse tumor models, which offer greater opportunity for detailed molecular genetic analysis of tumor initiation and progression. To explore the possible role of secondary genetic events in transgenic mouse mammary tumor development, we performed microsatellite-based allelotypes on primary mammary adenocarcinomas and lung metastases arising in mice transgenic for the polyomavirus middle T antigen under the control of the mouse mammary tumor virus promoter/enhancer (MMTV-MTAg mice) and on primary mammary adenocarcinomas arising in mice transgenic for the neu proto-oncogene (MMTV-neu mice). We examined a total of 80 microsatellite loci distributed throughout the mouse genome for LOH and observed high rates of specific chromosomal loss but very low rates of background allelic loss in these tumors. For the MMTV-MTAg mice, no individual chromosomes showed rates of LOH significantly above the background rates. For MMTV-neu mice, markers on chromosome 4 showed LOH in 82% of mammary tumors, whereas markers on chromosome 3 showed loss in 29% of tumors. These data suggest that the middle T antigen transgenic mice do not undergo whole chromosome loss or large genomic deletions as common mechanisms of tumor formation and that chromosomes 3 and 4 may contain tumor suppressor gene loci that play important roles in the development of neu-mediated mouse mammary tumors.
CD45-Positive Cells of the Retina and Their Responsiveness to In Vivo and In Vitro Treatment with IFN-γ or Anti-CD40 (2003)

Retinal MG were readily identified as the most numerous population. A small population of cells with perivascular cell (PVC)-like properties was found. They were CD45(hi)11c(+), some had elevated MHC class II, and they were affected by anti-CD40 treatment in vivo. No conventional DCs were found, although there was a distinct DEC-205(+) population. Overall, the effects of IFN-gamma and anti-CD40 treatment were attenuated in the retina in vivo and also on CD45(+) cells in culture, compared with the control.
Evolution of isoprenyl diphosphate synthase-like terpene synthases in fungi (2020)

Terpene synthases (TPSs) and trans-isoprenyl diphosphate synthases (IDSs) are among the core enzymes for creating the enormous diversity of terpenoids. Despite having no sequence homology, TPSs and IDSs share a conserved "α terpenoid synthase fold" and a trinuclear metal cluster for catalysis, implying a common ancestry with TPSs hypothesized to evolve from IDSs anciently. Here we report on the identification and functional characterization of novel IDS-like TPSs (ILTPSs) in fungi that evolved from IDS relatively recently, indicating recurrent evolution of TPSs from IDSs. Through large-scale bioinformatic analyses of fungal IDSs, putative ILTPSs that belong to the geranylgeranyl diphosphate synthase (GGDPS) family of IDSs were identified in three species of Melampsora. Among the GGDPS family of the two Melampsora species experimentally characterized, one enzyme was verified to be bona fide GGDPS and all others were demonstrated to function as TPSs. Melampsora ILTPSs displayed kinetic parameters similar to those of classic TPSs. Key residues underlying the determination of GGDPS versus ILTPS activity and functional divergence of ILTPSs were identified. Phylogenetic analysis implies a recent origination of these ILTPSs from a GGDPS progenitor in fungi, after the split of Melampsora from other genera within the class of Pucciniomycetes. For the poplar leaf rust fungus Melampsora larici-populina, the transcripts of its ILTPS genes were detected in infected poplar leaves, suggesting possible involvement of these recently evolved ILTPS genes in the infection process. This study reveals the recurrent evolution of TPSs from IDSs since their ancient occurrence and points to the possibility of a wide distribution of ILTPS genes in three domains of life.