gebhart/patrepeval huggingface dataset:
Guidelines for the verification and validation of expert system software and conventional software: User`s manual. Volume 7 (1995)

This report provides a step-by-step guide, or user manual, for personnel responsible for the planning and execution of the verification and validation (V&V), and developmental testing, of expert systems, conventional software systems, and various other types of artificial intelligence systems. While the guide was developed primarily for applications in the utility industry, it applies well to all industries. The user manual has three sections. In Section 1 the user assesses the stringency of V&V needed for the system under consideration, identifies the development stage the system is in, and identifies the component(s) of the system to be tested next. These three pieces of information determine which Guideline Package of V&V methods is most appropriate for those conditions. The V&V Guideline Packages are provided in Section 2. Each package consists of an ordered set of V&V techniques to be applied to the system, guides on choosing the review/evaluation team, measurement criteria, and references to a book or report which describes the application of the method. Section 3 presents details of 11 of the most important (or least well-explained in the literature) methods to assist the user in applying these techniques accurately.
Anthraquinones from a Marine-Derived Streptomyces spinoverrucosus (2012)

Four new anthraquinone analogues including galvaquinones A-C (1-3) and an isolation artifact, 5,8-dihydroxy-2,2,4-trimethyl-6-(3-methylbutyl)anthra[9,1-de][1,3]oxazin-7(2H)-one (4), were isolated from a marine-derived Streptomyces spinoverrucosus based on activity in an image-based assay to identify epigenetic modifying compounds. The structures of 1-4 were elucidated by comprehensive NMR and MS spectroscopic analysis. Galvaquinone B (2) was found to show epigenetic modulatory activity at 1.0 μM and exhibited moderate cytotoxicity against non-small-cell lung cancer (NSCLC) cell lines Calu-3 and H2887.
Fabrication of hierarchical MXene-based AuNPs-containing core–shell nanocomposites for high efficient catalysts (2017)

MXene is a new type of layered two-dimensional transition metal carbide materials differing from graphene, demonstrating intriguing chemical/physical properties. Here the chemical modification of MXene and next fabrication of core–shell MXene–[email protected](PEI/PAA)n composites have been investigated. The obtained MXene-based composites were treated with gold nanoparticles to form MXene–[email protected](PEI/PAA)n@AuNPs nanocomposites, and their catalytic properties for nitro-compounds were studied. The prepared nanocomposites demonstrated good catalytic activity and reproducibility, showing potential applications in composite catalysts and environmental fields.
Factors associated with using an interbody fusion device for low-grade lumbar degenerative versus isthmic spondylolisthesis: a retrospective cohort study (2021)

Although the demographic and patient characteristics associated with interbody device utilization differed between cohorts, similar proportions of patients attained clinically meaningful improvement at 1 year after surgery.
Cytosolic protein concentration is the primary volume signal for swelling-induced [K-Cl] cotransport in dog red cells. (1992)

Chloride-dependent K transport ([K-Cl] cotransport) in dog red cells is activated by cell swelling. Whether the volume signal is generated by a change in cell configuration or by the dilution of some cytosolic constituent is not known. To differentiate between these two alternatives we prepared resealed ghosts that, compared with intact red cells, had the same surface area and similar hemoglobin concentration, but a greatly diminished volume. Swelling-induced [K-Cl] cotransport was activated in the ghosts at a volume (20 fl) well below the activation volume for intact cells (70 fl), but at a similar hemoglobin concentration (30-35 g dry solids per 100 g wet weight). Ghosts made to contain 40% albumin and 60% hemoglobin showed activation of [K-Cl] cotransport at a concentration of cell solids similar to intact cells or ghosts containing only hemoglobin. [K-Cl] cotransport in the resealed ghosts became quiescent at a dry solid concentration close to that at which shrinkage-induced Na/H exchange became activated. These results support the notion that the primary volume sensor in dog red cells is cytosolic protein concentration. We speculate that macromolecular crowding is the mechanism by which cells initiate responses to volume perturbation.
Feasibility of a Fully Implanted, Nickel Sized and Shaped Tibial Nerve Stimulator for the Treatment of Overactive Bladder Syndrome with Urgency Urinary Incontinence (2018)

The implantable neuromodulation device was a safe and effective treatment of urgency urinary incontinence associated with overactive bladder syndrome with a significant reduction or resolution of symptoms and no significant safety concerns.
Fieldable Fourier transform spectrometer (2004)

The infrared sensors group at the Pacific Northwest National Laboratory (PNNL) is focused on the science and technology of remote and in-situ chemical sensors for detecting proliferation and countering terrorism. To support these vital missions, PNNL is developing frequency-modulation techniques for remote probing over long optical paths by means of differential-absorption light detecting and ranging (LIDAR). This technique can easily monitor large areas, or volumes, that could only be accomplished with a large network of point sensors. Recently, PNNL began development of a rugged frequency-modulation differential-abosrption LIDAR (FM-DIAL) system to conduct field experiments. To provide environmentla protection for the system and facilitate field deployments and operations, a large, well insulated, temperature controlled trailer was specified and acquired. The trailer was outfitted with a shock-mounted optical bench, an electronics rack, a liquid nitrogen Dewar, and a power generator. A computer-controlled gimbal-mounted mirror was added to allow the telescope beam to be accurately pointed in both the vertical and horizontal plane. This turned out to be the most complicated addition, and is described in detail. This paper provides an overview of the FM-DIAL system and illustrates innovative solutions developed to overcome several alignment and stability issues encountered in the field.
P4‐348: Evp‐6124: Safety, Tolerability And Cognitive Effects Of A Novel A7 Nicotinic Receptor Agonist In Alzheimer's Disease Patients On Stable Donepezil Or Rivastigmine Therapy (2009)

Approved symptomatic therapies for Alzheimer's disease (AD) provide modest relief. In the future, it is likely that symptomatic treatments will be utilized with AD modifying therapies, the development of which are currently a primary focus of research. The nicotinic a-7 receptor agonist may be an attractive drug candidate to potentially improve cognition in Alzheimer's disease patients either as a stand-alone therapy or in combination with other symptomatic treatments. EVP-6124 is a novel, potent, and selective alpha7 nicotinic receptor agonist. EVP-6124 has an excellent brain to plasma ratio and has shown excellent efficacy and potency in a number of animal models of cognition. Four clinical studies in healthy normal human subjects have been completed with EVP 6124. EVP-6124 exhibited linear kinetics over the range of 1 to 180mg and demonstrated a half-life suitable for once daily dosing. EVP 6124 appears to be safe and well-tolerated for up to 21 days as measured by adverse events, vital signs, continuous cardiac monitoring, physical examination, and clinical laboratory evaluations. In addition, in normal volunteers, EVP-6124 demonstrated pro-cognitive effects (CogState testing) in various cognitive domains including executive function. The safety and efficacy of EVP-6124 was assessed in a Phase 1b study of 48 mild to moderate AD patients 60-80 years of age, on stable donepezil or rivastigmine therapy. Patients were dosed with placebo or two different doses of EVP-6124 (0.3 or 1.0mg/d) for 28 days. Cognitive effects were measured by CogState computerized cognitive testing and a subset of NTB scales (category fluency, Trails A and B). EVP-6124 appeared to be safe and well tolerated with no significant adverse events reported more frequently in treated versus placebo patients; there were no SAEs reported. Subjects exposed to EVP-6124 in addition to donepezil or rivastigmine showed an increase in cognitive function, primarily in the domains of non-verbal learning, memory, and executive function. These data suggest that EVP-6124 administered to AD subjects on cholinesterase inhibitor therapies, may have a potential benefit. Larger phase II studies are currently being initiated in both Alzheimer's disease and schizophrenia.
Secure Combinatorial Optimization simulating DFS tree-based Variable Elimination (2006)

We report on two periapical lesions of endodontic origin detected in the maxillary bone of the same patient, whose echographic examination was used to address a tentative differential diagnosis between a granuloma and a cystic lesion. The patient on whom two periapical lesions were diagnosed with clinical and conventional radiographic findings and scheduled for endodontic surgery, was also examined using echography and color power doppler at the site of the lesions. The lesions were echographically described in each case according to a scheme from a previous work. A tentative differential diagnosis between a cystic lesion and a granuloma was made. One lesion was described as a cyst, the other as a granuloma. After surgical excision, the lesions were examined under light microscopy. In both cases the two echographic diagnoses were confirmed by the histopathologic examination.
Should Molluscum Be Treated? (1980)

Major textbooks of pediatrics1-7 and dermatology8-11 as well as special editions on pediatric dermatology12 suggest that molluscum contagiosum requires treatment in infants and children. Pricking the surface of the lesion and expressing the contents is the most frequently recommended therapy1,4-7,9,11 but curettage is also frequently suggested.2-4,6,7,10 Podophyllin, Cantharone, trichloroacetic acid, benzoyl peroxide gels, phenol, glacial acetic acid, liquid nitrogen cryotherapy, surgical excision, oral tetracycline, and thiosemicarbazol are suggested in one or another of these references as alternative measures.
1P2-R02 Comparison and evaluation of unified laundry folding method and human laundry folding method (2015)

In this study, we aim to deal with the laundries by two robot arms and a camera. We evaluated how folds laundry in the unified method in comparison with folding by human. As a result, a good condition which is used the laundry by human is the fewer number of folding. And a good condition which is put away the laundry by human is the smaller laundry. The size of laundry which is folded by unified method is about 12.5 to 25% of the original size after folding the square.
Experiences of junior public health nurses in delivery of maternal healthcare services to tribal women in Kerala (2013)

The JPHNs serving in tribal areas overcame various constraints in service delivery like hilly terrain, limited public transport facilities, long hours spent in travelling, cultural and language barriers by putting in extra effort, time and personal money to fulfill their responsibilities. It is suggested that the JPHNs be given compensatory off to complete records and extra remuneration to cover their out of pocket expenditure on travelling to difficult areas.
The synthesis of aqueous-dispersible anatase TiO2nanoplatelets (2009)

Aqueous well-dispersed and phase-pure anatase TiO(2) truncated octahedron nanoplatelets (NPLs) were prepared via controlled hydrolysis of titanium tetrachloride (TiCl(4)) in ethylene glycol at 240 degrees C. Two shapes, square and hexagon, were observed by microscopy, exactly corresponding to the truncated octahedron NPLs. Ethylene glycol was found to produce water in situ that reacts with TiCl(4) to produce TiO(2) and HCl-the latter promoting TiO(2) colloid peptization. TiO(2) truncated octahedron NPLs are formed under the stabilizing action of ethylene glycol thermolysis derivatives, such as aldehydes. Crystal growth of the TiO(2) NPLs was affected by the reaction temperature that determines the water production rate and HCl-assisted peptization. TGA and FT-IR results showed approximately 1.2% ethylene glycol thermolysis derivatives are attached to the surface of the TiO(2) NPLs, which prevents their agglomeration, hence making them easily dispersible in aqueous media. HR-TEM and SAED results showed that the TiO(2) NPLs are well crystallized and that the SAED patterns of the single TiO(2) NPL changes with its size and shape. XRD patterns showed that the TiO(2) NPLs are phase-pure anatase and the percentage of the [101] plane in the TiO(2) NPLs to be only 18%-a structural feature that renders the TiO(2) NPLs with enhanced UV absorption and reactivity properties.
Test set compaction for combinational circuits (2003)

Test set compaction for combinational circuits is studied. Two active compaction methods, forced pair-merging and essential fault pruning, are developed to reduce a given test set. Together these two methods, the compacted test size is smaller than known best results by more than 20% and is only 20% larger than the established lower bound.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Synthesis and Structures of Hydrazinoalanes and Hydrido(hydrazino)aluminates⋆ (1998)

Several monomeric dimethylaluminium hydrazide ether adducts Et2O/THF × Me2AlNR–NR′R′′ (5–7) were obtained by deprotonating the respective hydrazines with nBuLi, followed by reaction with Me2AlCl. The hydrazines Ph(H)N–N(SiMe3)2 and tBu(H)N–N(H)SiMe3 react with LiAlH4 in the presence of either ether or THF with the formation of dimeric lithium hydrazino(hydrido)aluminates, e.g. 8 and 9. Their structures depend on the number of acidic hydrogen atoms bonded to the nitrogen atoms of the starting hydrazine. The hydrazine Ph(H)N–N(SiMe3)2 (1) reacts with LiAlH4 to form monometallated LiAlH3[(Ph)N–N(SiMe3)2] × 2 Et2O (8) with elimination of one equivalent of H2. The molecule is dimeric and features an (AlHLiH)2 eight-membered ring. In contrast, the reaction of tBu(H)N–N(H)SiMe3 with LiAlH4 in the presence of THF leads to the formation of dimeric 2 THF × LiAlH2[(tBu)N–N(SiMe3)] (9) with a central (AlNN)2 six-membered ring. A dimeric aluminium hydrazide 10 was obtained by allowing tBu(Li)N–N(H)SiMe3 to react with Me2AlCl in a hexane/toluene solution. The structure of 10 features a six-membered Al2N4 ring in chair conformation.
Novel modification of cyanate ester by epoxidized polysiloxane (2007)

Abstract A novel modification of cyanate ester (CE) resin by epoxidized polysiloxane (E‐Si) has been developed, and the modified system is coded as CE/E‐Si. E‐Si was prepared by the reactions among octamethylcyclotetrasiloxane, hexamethyldisiloxane, (3‐aminopropyl)‐methyldiethoxysilane, and diglycidyl ether of bisphenol‐A resin. Six formulations were designed to evaluate the effect of the weight ratio between CE and E‐Si on performance parameters. Results reveal that the addition of E‐Si in CE resin cannot only significantly decrease the curing temperature of the CE resin but also improve the water resistance and toughness of original CE resin. Moreover, these positive effects increase with the increase of E‐Si concentration in CE/E‐Si systems. Thermal property investigation shows that the glass‐transition temperature and initial degradation temperature of CE/E‐Si systems are lower than that of original CE resin. For the flexural properties of the CE/E‐Si systems, the E‐Si concentration in the system exists a threshold, that is, when the E‐Si concentration is smaller than the threshold, original CE and CE/E‐Si systems have similar flexural properties, whereas when the E‐Si concentration is higher than the threshold, CE/E‐Si systems have lower flexural properties than original CE resin. All these changes of properties are closely correlated to the structure alteration from neat CE to CE/E‐Si networks. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci 2007
Genetic Aspects of Longevity in Angus and Hereford Cows (1988)

Thirty years and 23 yr of life history data from a Hereford herd in Arizona and an Angus herd in Wyoming, respectively, were analyzed. Longevity averaged 4.21 +/- .06 for years from first calving to disposal (FST), 7.40 +/- .06 for years from birth to disposal (AGE) and 3.46 +/- .06 for lifetime number of calves weaned (NUM) in Herefords and 4.49 +/- .13 (FST), 6.68 +/- .12 (AGE) and 3.66 +/- .11 (NUM) in Angus. In the Hereford herd, heritability estimates for traits measuring longevity, estimated from daughter-dam regression and paternal half-sib analyses, ranged from .16 to .26. In the Angus herd, heritability estimates from daughter-dam regression ranged from .03 to .05. In the Hereford herd, genetic correlations of birth weight and weaning weight with longevity, from daughter-dam regression, were negative and generally of low magnitude, whereas genetic correlations between weaning condition score and longevity were positive and moderate. Analogous estimates from paternal half-sib analyses all were positive and moderate to high. Phenotypic correlations between early life traits and longevity traits in Herefords all were near zero. In the Angus herd, curves for age-specific survivorship and age-specific survival rate varied markedly among sires. This study suggested the existence of moderate genetic variation for longevity traits in beef cattle. None of the traits expressed early in life that were examined would, however, be reliable predictors of genetic or phenotypic merit for longevity.
Collective transport of arbitrarily shaped objects using robot swarms (2022)

Abstract Out-of-the-box swarm solutions powering industrial logistics will need to adapt to the tasks at hand, coordinating in a distributed manner to transport objects of different sizes. This work designs and evaluates a collective transport strategy to move large and arbitrarily shaped objects in warehouse environments. The strategy uses a decentralized recruitment and decision-making process, ensuring that sufficient robots are in place for a coordinated, safe lift and transport of the object. Results show robots having no prior knowledge about the object’s size and shape were successfully able to transport them in simulation.
Visualization of a Covalent Intermediate between Microsomal Epoxide Hydrolase, but not Cholesterol Epoxide Hydrolase, and their Substrates (1997)

Mammalian soluble and microsomal epoxide hydrolases have been proposed to belong to the family of alpha/beta-hydrolase-fold enzymes. These enzymes hydrolyse their substrates by a catalytic triad, with the first step of the enzymatic reaction being the formation of a covalent enzyme-substrate ester. In the present paper, we describe the direct visualization of the ester formation between rat microsomal epoxide hydrolase and its substrate. Microsomal epoxide hydrolase was precipitated with acetone after brief incubation with [1-(14)C]epoxystearic acid. After denaturing SDS gel electrophoresis the protein-bound radioactivity was detected by fluorography. Pure epoxide hydrolase and crude microsomes showed a single radioactive signal of the expected molecular mass that could be suppressed by inclusion of the competitive inhibitor 1,1,1-trichloropropene oxide in the incubation mixture. In a similar manner, 4-fluorochalcone-oxide-sensitive binding of epoxystearic acid to rat soluble epoxide hydrolase could be demonstrated in rat liver cytosol. Under similar conditions, no covalent binding of [26-(14)C]cholesterol-5alpha,6alpha-epoxide to microsomal proteins or solubilized fractions tenfold enriched in cholesterol epoxide hydrolase activity could be observed. Our data provide definitive proof for the formation of an enzyme-substrate-ester intermediate formed in the course of epoxide hydrolysis by microsomal epoxide hydrolase, show no formation of a covalent intermediate between cholesterol epoxide hydrolase and its substrate under the same conditions as those under which an intermediate was shown for both microsomal and soluble epoxide hydrolases and therefore indicate that the cholesterol epoxide hydrolase apparently does not act by a similar mechanism and is probably not structurally related to microsomal and soluble epoxide hydrolases.
Hemophilia A and B: molecular and clinical similarities and differences (2019)

Hemophilia A and B are rare X-linked bleeding disorders caused by mutations in the genes encoding coagulation factor VIII (FVIII) and factor IX (FIX). Hemophilia A (HA) is more common than hemophilia B (HB), with a prevalence of one in 5,000 male live births compared to one in 30,000, respectively.[
Resource Allocation Schemes for Revenue Maximization in Multicast D2D Networks (2017)

Mobile users' service satisfaction plays a vital role in improving the revenue of telecom companies. When user data demands are uniform, satisfying the user requests is much easier than when demands are diverse. Yet, in a multicast scenario, each user may wish to view the same multicast data at different bit rates based on their own device capacities or resolutions. In this paper, we consider device-to-device (D2D) multicast users who may demand the multicast data at various rates, and in return, they offer different profits (revenue) to the telecom operator. Moreover, users may have different channel qualities from the base station, which will also affect the data rates. We show that satisfying the user requests to maximize the profit becomes NP-hard when the resource blocks are limited, and propose a greedy heuristic and two approximation algorithms to solve this problem. Besides, we consider an alternative objective of maximizing the number of satisfied users and propose a greedy heuristic algorithm for this variant. Our simulation results demonstrate that the proposed algorithms offer higher profit, throughput, and satisfy more users than the other candidate algorithms.
Semantic Signatures for Example-Based Linguistic Metaphor Detection (2013)

Metaphor is a pervasive feature of human language that enables us to conceptualize and communicate abstract concepts using more concrete terminology. Unfortunately, it is also a feature that serves to confound a computer’s ability to comprehend natural human language. We present a method to detect linguistic metaphors by inducing a domainaware semantic signature for a given text and compare this signature against a large index of known metaphors. By training a suite of binary classifiers using the results of several semantic signature-based rankings of the index, we are able to detect linguistic metaphors in unstructured text at a significantly higher precision as compared to several baseline approaches. 1
Measurement of Pulse Front Distortion Caused by Aberrations Using Spectral Interferometry (2010)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation K. Mecseki, A. P. Kovács, Z. L. Horváth; Measurement of Pulse Front Distortion Caused by Aberrations Using Spectral Interferometry. AIP Conference Proceedings 16 April 2010; 1228 (1): 190–196. https://doi.org/10.1063/1.3426050 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search