gebhart/patrepeval huggingface dataset:
Abstract 276: The Impact of Ventricular Assist Devices on Blood Product Utilization for Cardiac Transplantation (2011)

Purpose: Ventricular assist device (VAD) support as a bridge to cardiac transplantation has introduced device-related complications to cardiac surgery. Specifically, therapeutic anticoagulation in newer generational devices is a primary challenge. The purpose of this study was to examine whether blood product utilization and mortality significantly differ for VAD patients compared to non-VAD (NVAD) patients following cardiac transplantation. Methods: From 2004-2010, 76 patients underwent cardiac transplantation at a single institution. Patients were stratified by VAD presence at transplantation: VAD patients (n=40, age: 50.8±11.0 years) vs. NVAD patients (n=36, age: 48.6±12.3 years). The primary outcomes of interest were blood product transfusion requirements and 30-day mortality. Results: Preoperative patient characteristics were similar for VAD and NVAD patients. NVAD patients presented with higher median preoperative creatinine levels compared to VAD patients (1.3 [1.10-1.58] vs. 1.1 [0.93-1.38], P=0.01). In addition, more NVAD patients required preoperative ACE-inhibitor therapy (P&lt;0.001). Preoperative warfarin therapy was expectedly more common among VAD patients (P&lt;0.001). Importantly, VAD patients accrued higher intra-operative transfusion of all blood products (all P&lt;0.001) as well as higher postoperative packed red blood cell transfusions (P=0.04) compared to NVAD patients (Table). 30-day mortality was not significantly different between groups (7.5% vs. 8.3%, P&gt;0.99). Conclusions: VAD support and the inherent requirement for anti-coagulation have significantly increased blood product utilization for cardiac transplantation. Despite these requirements, mortality rates remain similar to that of NVAD patients undergoing transplantation. Further study to define an optimal preoperative anticoagulation strategy for VAD patients may help to decrease the future resuscitative burden for cardiac transplantation.
Rational Design of Right-Handed Heterogeneous Peptidomimetics as Inhibitors of Protein–Protein Interactions (2020)

Peptidomimetics have gained great attention for their function as protein-protein interaction (PPI) inhibitors. Herein, we report the design and investigation of a series of right-handed helical heterogeneous 1:1 α/Sulfono-γ-AA peptides as unprecedented inhibitors for p53-MDM2 and p53-MDMX. The most potent helical heterogeneous 1:1 α/Sulfono-γ-AA peptides were shown to bind tightly to MDM2 and MDMX, with <i>K</i><sub>d</sub> of 19.3 and 66.8 nM, respectively. Circular dichroism spectra, 2D-NMR spectroscopy, and the computational simulations suggested that these helical sulfono-γ-AA peptides could mimic the critical side chains of p53 and disrupt p53/MDM2 PPI effectively. It was noted that these 1:1 α/Sulfono-γ-AA peptides were completely resistant to proteolytic degradation, boosting their potential for biomedical applications. Furthermore, effective cellular activity is achieved by the stapled 1:1 α/Sulfono-γ-AA peptides, evidenced by significantly enhanced p53 transcriptional activity and much more induced level of MDM2 and p21. The 1:1 α/Sulfono-γ-AA peptides could be an alternative strategy to antagonize a myriad of PPIs.
The Role of the Adrenal Gland in Ethanol-Induced Triglyceride Mobilization (1984)

The effect of a large ethanol (ETOH) dose (4.8 g/kg) on triglyceride (TG) levels of plasma, brain and liver was studied in the rat. TG levels were measured in fasted male rats treated with ETOH or after ETOH and tetraethylammonium treatment in intact rats. The levels of TG were also measured after treatment with ETOH and dexamethasone (DXM) in adrenalectomized rats. Plasma TG levels significantly increased in the nonadrenalectomized and adrenalectomized rats by one- and twofold respectively. Brain TG levels increased significantly when intact animals were placed under either stress or when they were treated with ETOH and stress simultaneously. The adrenalectomized rats showed a similar response when they were treated with ETOH and DXM simultaneously. The liver TG levels were significantly different from control in all treated animals. The ETOH-treated adrenalectomized rats' TG levels were significantly less than control. This study suggests that stress and the adrenal gland play important roles in ETOH-induced TG levels in the rat.
An Equal Protection Analysis of Restrictive Abortion Laws: Affirmative Steps to Protect Woman's Liberty (1990)

This Note is a response to the United States Supreme Court's Continuing erosion of the fundamental right to privacy, which was held in Roe v. Wade to encompass a woman's decision to terminate her Pregnancy. Roe v. Wade focused solely on the fourteenth amendments due process clause2 as the source of the abortion right. This Note will argue that this important right should also be grounded in the fourteenth amendment's equal protection clause.
Calibration with Many Variables (1993)

Multivariate calibration involves the use of an estimated relationship between a multivariate response vector Y and an explanatory vector X to predict unknown X in future from further observed responses. With modern instrumentation the dimension of the response vector may be very large (of the order 1000) and yet the number of observations small. Under such circumstances standard approaches to calibration give rise to non-unique predictors of future X. To obtain a unique estimator it is necessary to impose additional structure. We investigate various approaches to dimension reduction to do this. Areas of application are the food and chemical industries
Waypointing and social tagging to support program navigation (2006)

As the "software space" of source code, documentation, models, and other programming artifacts continue to grow in size and complexity, programmers face the challenge of navigating this space, as well as documenting and sharing their journeys for other developers and future successors. Current navigational structures are either closely tied to the semantics of the software or are constructed in a constrained top-down fashion to match the architecture or requirements of the system. In this paper, we introduce the notion of combining waypoints from geographical positioning and social tagging from shared bookmark systems to allow programmers to create shared, tagged points in software space. We report preliminary progress on our prototype (tagSEA), and discuss our future plans.
Versatile laser and optical amplifier for ultrafast imaging (2018)

Photonic technologies revolutionize optical imaging, from source generation to signal detection. Here we report MHz broadband swept sources for ultrafast imaging modalities. Their performance can be enhanced by broadband and sensitive fiber optical parametric amplifier.
Behaviour of isolated rat and human red blood cells upon hypotonic-dialysis encapsulation of carbonic anhydrase and dextran. (1996)

Rat and human carrier red blood cells (RBCs) were prepared by hypotonic-dialysis encapsulation. The standard conditions used for encapsulation were 80 mOsm/kg for 60 min. The encapsulation behaviour of rat and human RBCs was studied using radiolabelled carbonic anhydrase and fluorescently labelled dextran. Both markers are incorporated to slightly greater extents by human than by rat RBCs by hypotonic treatment. Cell recovery of rat and human RBCs loaded with either carbonic anhydrase or fluorescent dextran accounted for 49% and 80% respectively. The cellular integrity of the loaded cells was revealed by the presence of fluorescence labelling in rat and human RBCs. Fluorescence studies showed an increase of size dispersion in loaded rat and human RBCs, giving cellular volume variations in both types of cells resulting from the encapsulation procedure. Two loaded cell populations were evident in both species, one with high fluorescence content and another with background staining. Apparently the proportion of high fluorescently labelled loaded cells was higher in the case of the human RBCs. A reduced level of fluorescence labelling was observed in rat and human RBC membranes, which indicates a process of adsorption of dextran to the membranes.
The 30-kDa and 38-kDa antigens from Mycobacterium tuberculosis induce partial maturation of human dendritic cells shifting CD4+ T cell responses towards IL-4 production (2013)

Together our data indicate that 30-kDa and 38-kDa Mtb antigens induced only partial DC maturation shifting immune responses towards a Th2 profile.
Improved Positioning Precision using a Multi-rate Multi-sensor in Industrial Motion Control Systems (2023)

Industrial motion control systems, e.g. pick-andplace tasks in semiconductor manufacturing equipment, require precise positioning for achieving high machine throughput. Linear encoders are the standard industrial sensors used for position feedback due to their relatively low cost, high resolution, and high operating frequency. The challenge is that the linear encoders measure the positions at the points-ofcontrol of the equipment, e.g. motors, and not at the points-ofinterest, e.g. pick-and-place positions. The coupling between a point-of-control and the point-of-interest is affected by external disturbances such as mechanical misalignment of the product, friction, and warping of the material, and linear encoders fail to sense these disturbances. Vision-based sensing is a potential alternative to achieve robust sensing and high-precision control. However, vision processing has a long computational delay and affects the machine throughput. In this paper, we propose a multi-rate multi-sensor fusion approach to improve the positioning accuracy of industrial motion control systems with different points-of-control and points-of-interest. We present a multi-rate Kalman filter with bias correction to fuse accurate but slow and delayed vision sensor data with fast but less accurate linear encoder data for highprecision position control. We validate the proposed method in an evaluation framework by considering an industrial case study of a semiconductor die-bonding machine. A design-space exploration is done to evaluate the performance of the proposed solution with respect to various relevant design parameters. The effectiveness of the proposed solution depends on the type of disturbances and vision processing delay. For the parameter range under consideration, we achieve a positioning accuracy of 1μm.
InGaP/GaAs Heterojunction Bipolar Transistors with an Ultra-High Carbon-Doped Base (p=1.5×1021cm-3) (1995)

In 0.5 Ga 0.5 P/GaAs heterojunction bipolar transistors (HBTs) having a heavily carbon (C)-doped GaAs base with an ultra-high hole concentration of 1.5×10 21 cm -3 were successfully fabricated by metalorganic molecular beam epitaxy (MOMBE) for the first time. Tertiarybutylphosphine (TBP), elemental In and elemental Ga were used as source materials for the growth of In 0.5 Ga 0.5 P emitter and trimethylgallium (TMG) and elemental arsenic ( As 4 ) for the growth of GaAs base. Abrupt change of composition was obtained at the heterointerface between InGaP emitter and heavily C-doped GaAs base, suggesting no defect formation due to heavy doping in the base. Small signal current gain ( h fe ) of 16 and DC current gain ( h FE ) of 12 were obtained for devices with a base thickness of 15 nm despite the ultra-high doping in the base layer. To our knowledge, this is the first report on the InGaP/GaAs HBTs with an ultra-high C-doped base layer.
Defining trust evidence (2011)

research-article Share on Defining trust evidence: research directions Authors: Claire Vishik View Profile , Anand Rajan View Profile , Chris Ramming View Profile , David Grawrock View Profile , Jesse Walker View Profile Authors Info & Claims CSIIRW '11: Proceedings of the Seventh Annual Workshop on Cyber Security and Information Intelligence ResearchOctober 2011 Article No.: 66Pages 1https://doi.org/10.1145/2179298.2179373Published:12 October 2011Publication History 2citation227DownloadsMetricsTotal Citations2Total Downloads227Last 12 Months21Last 6 weeks3 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my Alerts New Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Harmonisation and Dosimetric Quality Assurance in Individual Monitoring for External Radiation (2001)

The current situation amongst Member States is that there are widely differing national requirements for dosimetric services and for dosemeter performance. It is clear that with the free movement of workers within the European Union (EU) and the requirements for individual dosimetry given in Council Directive 96/29 EURATOM, a degree of harmonisation of requirements and procedures of EU Member States would be desirable. A EURADOS action group, made up of members from each of the EU Member States plus Switzerland, was set up with the overall objectives of consolidating within the EU the quality of individual monitoring using personal dosemeters and assisting movement towards harmonised procedures. An outline of the work of the action group is given and the term 'harmonisation' is discussed.
Improvement of InGaP/GaAs heterointerface quality by controlling AsH3 flow conditions (1999)

Heterointerfaces between disordered InGaP on GaAs, whose conduction band offset, ΔEc, is 0.2 eV, can be improved and have less interface charges by controlling the AsH3 cover time and flow rate at the growth interval from GaAs to InGaP by metalorganic chemical vapor deposition. A small AsH3 cover of 5 cc (0.05 min with 100 cc/min) creates a low interface charge density, σ, of 6.4×1010 cm−2. Extending the AsH3 cover to only 25 cc increases σ by one order, even though AsH3 is purged by PH3 for a rather long time after being covered. Interface charges are confirmed to be donors whose energy level is near the conduction band edge. These results show that excess As on the GaAs surface enhances the formation of donor-like defects in the InGaP layer. An As-poor GaAs surface is essential in order to achieve high-quality InGaP/GaAs heterointerfaces.
Silicon and Silicon Alloys, Chemical and Metallurgical (2000)

Abstract Silicon is a low density element having nonmetallic characteristics. The production of silicon from silica is discussed as is silicon refining technology. The primary uses of silicon are in the chemical, aluminum, and electronics industries. Silicon is the chemical precursor of silicones, a versatile, fast‐growing market, and of advanced ceramics such as silicon nitride. Silicon forms an integral part of the aluminum parts industry; aluminum–silicon alloys are readily cast. Silicon is also important to aluminum production. Silicon forms alloys with a large number of metallic elements. Many of these alloys are of utmost importance to the production and refining of irons and steels. The most prevalent are the ferrosilicons, production of which is discussed.
Determining Difficulty of Questions in Intelligent Tutoring Systems. (2009)

Plants survive against myriad environmental odds while remaining rooted to a single spot. The time scale over which plant cells can respond to environmental cues is seldom appreciated. Fluorescent protein-assisted live imaging of peroxisomes reveals that they respond within seconds of exposure to hydrogen peroxide and hydroxyl radicals by producing dynamic extensions called peroxules. Observations of the Arabidopsis flu mutant and treatments with xenobiotics eliciting singlet oxygen and superoxide reactive oxygen species suggest that the observed responses are specific for hydroxyl radicals. Prolonged exposure to hydroxyl radicals inhibits peroxule extension, and instead causes motile and spherical peroxisomes in a cell to become immotile and elongate several-fold. Expression of photo-convertible EosFP-PTS1 demonstrates that vermiform peroxisomes result from rapid stretching of individual peroxisomes, while the subsequent 'beads-on-a-string' morphology results from differential protein distribution within an elongated tubule. Over time, the beads in elongated peroxisomes also extend peroxules randomly before undergoing asynchronous, asymmetrical fission. Peroxule extension does not appear to involve cytoskeletal elements directly, but is closely aligned with and reflects the dynamics of ER tubules. Peroxisomal responses reveal a rapidly invoked subcellular machinery that is involved in recognition of hydroxyl stress thresholds, and its possible remediation locally through extension of peroxules or globally by increasing peroxisome numbers. A matrix protein retro-flow mechanism that supports peroxisome-ER connectivity in plant cells is suggested.
HARC-New Hybrid Method with Hierarchical Attention Based Bidirectional Recurrent Neural Network with Dilated Convolutional Neural Network to Recognize Multilabel Emotions from Text (2021)

We present a modern hybrid paradigm for managing tacit semantic awareness and qualitative meaning in short texts. The main goals of this proposed technique are to use deep learning approaches to identify multilevel textual sentiment with far less time and more accurate and simple network structure training for better performance. In this analysis, the proposed new hybrid deep learning HARC model architecture for the recognition of multilevel textual sentiment that combines hierarchical attention with Convolutional Neural Network (CNN), Bidirectional Gated Recurrent Unit (BiGRU), and Bidirectional Long Short-Term Memory (BiLSTM) outperforms other compared approaches. BiGRU and BiLSTM were used in this model to eliminate individual context functions and to adequately manage long-range features. Dilated CNN was used to replicate the retrieved feature by forwarding vector instances for better support in the hierarchical attention layer, and it was used to eliminate better text information using higher coupling correlations. Our method handles the most important features to recover the limitations of handling context and semantics sufficiently. On a variety of datasets, our proposed HARC algorithm solution outperformed traditional machine learning approaches as well as comparable deep learning models by a margin of 1%. The accuracy of the proposed HARC method was 82.50 percent IMDB, 98.00 percent for toxic data, 92.31 percent for Cornflower, and 94.60 percent for Emotion recognition data. Our method works better than other basic and CNN and RNN based hybrid models. In the future, we will work for more levels of text emotions from long and more complex text.
Dual Antiplatelet Therapy With Clopidogrel and Aspirin in Symptomatic Carotid Stenosis Evaluated Using Doppler Embolic Signal Detection (2005)

In patients with recently symptomatic carotid stenosis, combination therapy with clopidogrel and aspirin is more effective than aspirin alone in reducing asymptomatic embolization. Doppler MES detection is a feasible method to evaluate the efficacy of antiplatelet therapy in multicenter studies.
Privacy-Preserving Proof of Storage for the Pay-As-You-Go Business Model (2019)

Proof of Storage (PoS) enables a cloud storage provider to prove that a client's data is intact. However, existing PoS protocols are not designed for the pay-as-you-go business model in which payment is made based on both storage volume and duration. In this paper, we propose two PoS protocols suitable for the pay-as-you-go storage business model. The first is a time encapsulated Proof of Retrievability (PoR) protocol that ensures retrievability of the original file upon successful auditing by a client. Considering the large size of outsourced data, we then extend the protocol to a privacy-preserving public auditing protocol which allows a third party auditor to audit outsourced data on behalf of its clients without sacrificing the privacy of the data or the timestamp (i.e., time of storage). We formalize the definition, system model and security model of the proposed PoS system and prove the security of the proposed protocols by a sequence of games in the algebraic group model with a random oracle. We analyze the performance of the protocols both theoretically and experimentally and show that the protocols are practical.
Temperature-aware routing in 3D ICs (2006)

3D integrated circuits (3D ICs) provide an attractive solution for improving circuit performance. Such solutions must be embedded in an electrothermally-conscious design methodology, since 3D ICs generate a significant amount of heat per unit volume. In this paper, we propose a temperature-aware 3D global routing algorithm with insertion of "thermal vias" and "thermal wires" to lower the effective thermal resistance of the material, thereby reducing chip temperature. Since thermal vias and thermal wires take up lateral routing space, our algorithm utilizes sensitivity analysis to judiciously allocate their usage, and iteratively resolve contention between routing and thermal vias and thermal wires. Experimental results show that our routing algorithm can effectively reduce the peak temperature and alleviate routing congestion.
899: Investigation of High Intensity Focused Ultrasound Ablation in Isolated Kidneys by MRI- (2007)

You have accessJournal of UrologyModerated Poster 26, Monday, May 21, 2007, 1:00 - 3:00 pm1 Apr 2007899: Investigation of High Intensity Focused Ultrasound Ablation in Isolated Kidneys by MRI- Axel Haecker, Kristina Peters, Peter Alken, Maurice S. Michel, and Jürgen Jenne Axel HaeckerAxel Haecker More articles by this author , Kristina PetersKristina Peters More articles by this author , Peter AlkenPeter Alken More articles by this author , Maurice S. MichelMaurice S. Michel More articles by this author , and Jürgen JenneJürgen Jenne More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)31127-3AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "899: Investigation of High Intensity Focused Ultrasound Ablation in Isolated Kidneys by MRI-." The Journal of Urology, 177(4S), pp. 298–299 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 177Issue 4SApril 2007Page: 298-299 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Axel Haecker More articles by this author Kristina Peters More articles by this author Peter Alken More articles by this author Maurice S. Michel More articles by this author Jürgen Jenne More articles by this author Expand All Advertisement PDF downloadLoading ...
New magnetic configuration in paramagnetic phase of HoCo2 (2012)

X-ray magnetic circular dichroism (XMCD) measurements on HoCo2 reveal the inversion of Co moment at temperatures higher than the critical temperature, Tc, showing that the net magnetization under a field of the Ho and Co sublattices remain antiparallel even above Tc. The Ho moment also changes its orientation to align antiparallel to the applied field at high temperature giving rise to a new magnetic configuration in the paramagnetic regime. Transverse susceptibility (TS) and small angle neutron scattering (SANS) measurements performed above Tc indicate the existence of sizable magnetic short-range correlated regions in HoCo2. First principles calculations based on spin polarized local-density approximation, LSDA+U havebeen performed to obtain insights on the origin of the short-range correlated volume.