gebhart/patrepeval huggingface dataset:
Kinetics of sodium ion-induced calcium(2+) release in calcium(2+) loaded cardiac sarcolemmal vesicles: determination of initial velocities by stopped-flow spectrophotometry (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTKinetics of sodium ion-induced calcium(2+) release in calcium(2+) loaded cardiac sarcolemmal vesicles: determination of initial velocities by stopped-flow spectrophotometryMasaaki Kadoma, Jeffrey Froehlich, John Reeves, and John SutkoCite this: Biochemistry 1982, 21, 8, 1914–1918Publication Date (Print):April 13, 1982Publication History Published online1 May 2002Published inissue 13 April 1982https://pubs.acs.org/doi/10.1021/bi00537a033https://doi.org/10.1021/bi00537a033research-articleACS PublicationsRequest reuse permissionsArticle Views32Altmetric-Citations25LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Power Microtransformer on Silicon Embedded into PCB (2021)

In this work, a feasibility concept for packaging microtransformer devices with integrated magnetic core fabricated on silicon wafers is presented. For packaging, the embedding technology into PCBs is applied. The microtransformer chips with size of 2.5 mm x 2.0 mm are embedded into PCB package with a size of 3.3 mm x 3.0 mm. The profile height of 0.45 mm is achieved for microtransformer devices which were removed from silicon substrate. Electrical test of packaged devices show the reduction of parasitic effects and improvement of electrical performances.
Extracts fromBlighia sapida (Koenig) Produce Neutropenia and Thrombocytopenia in Mice (1996)

Neutrophil and platelet counts were significantly lowered (p<0.05) in mice treated with aqueous and lipid extracts of the unripe fruit of Blighia sapida. The percentage reduction in neutrophil and platelet counts relative to the controls for the aqueous and lipid (data in parentheses) extracts were 63.4% (59.3%) and 37.46% (32.44%) respectively after 6 weeks of treatment. The significant reduction in neutrophil and platelet numbers suggests that these extracts may be useful in disease conditions where these two blood parameters are elevated, for example chronic myeloid leukaemia, essential thrombocythaemia and polycythaemia.
Extension of the theory of the disk parametric array (1977)

In an earlier paper [J. C. Lockwood, J. Acoust. Soc. Am. 56, 1293–1294 (1974)], Lockwood analyzed a parametric acoustic array, the primary field of which is a thin disk of cylindrically spreading waves. This primary wavefield is perfectly collimated in one coordinate direction and omnidirectional in another, thus is a first step in a treatment of the fan beam. He assumes that finite-amplitude attenuation is not significant. The present paper extends Lockwood's analysis to the case of a sector of the disk; that is where the primary wavefield is no longer omnidirectional in one coordinate direction, but has a beamwidth less than 2π. Also, a taper function appropriate to cylindrical spreading is introduced to account for significant finite-amplitude attenuation.
Multi-environment QTL analysis of plant and flower morphological traits in tetraploid rose (2018)

Rose morphological traits such as prickles or petal number are influenced by a few key QTL which were detected across different growing environments-necessary for genomics-assisted selection in non-target environments. Rose, one of the world's most-loved and commercially important ornamental plants, is predominantly tetraploid, possessing four rather than two copies of each chromosome. This condition complicates genetic analysis, and so the majority of previous genetic studies in rose have been performed at the diploid level. However, there may be advantages to performing genetic analyses at the tetraploid level, not least because this is the ploidy level of most breeding germplasm. Here, we apply recently developed methods for quantitative trait loci (QTL) detection in a segregating tetraploid rose population (F<sub>1</sub> = 151) to unravel the genetic control of a number of key morphological traits. These traits were measured both in the Netherlands and Kenya. Since ornamental plant breeding and selection are increasingly being performed at locations other than the production sites, environment-neutral QTL are required to maximise the effectiveness of breeding programmes. We detected a number of robust, multi-environment QTL for such traits as stem and petiole prickles, petal number and stem length that were localised on the recently developed high-density SNP linkage map for rose. Our work explores the complex genetic architecture of these important morphological traits at the tetraploid level, while helping to advance the methods for marker-trait exploration in polyploid species.
A Family Of Pou-Domain And Pit-1 Tissue-Specific Transcription Factors In Pituitary And Neuroendocrine Development (1990)

Macrophage polarization refers to how macrophages have been activated at a given point in space and time. Polarization is not fixed, as macrophages are sufficiently plastic to integrate multiple signals, such as those from microbes, damaged tissues, and ...Read More
Large Scale, Analytical Method for Isolating Basal Lateral Plasma Membranes from Rat Duodenum (1979)

A procedure is described for obtaining large amounts of basal lateral plasma membranes from the rat duodenal epithelium. The yield is approximately 50%, and the purification factor is 18; preparations from 25 rats routinely contain 100 mg of protein. The procedure depends on mild homogenization with a nitrogen cavitation bomb, followed by removal of brush borders by sedimentation in a weak centrifugal field. Basal lateral membranes in the resulting supernatant are partially purified by differential centrifugation in a medium which approximates their equilibrium density, and then further purified by equilibrium density gradient centrifugation in a high capacity zonal rotor. Brush border membranes may be isolated from the 450 x g pellet. Since both brush border and basal lateral membranes may be isolated from the same homogenate, this preparative procedure is suitable for such analytical purposes as determinations of distribution of enzyme activities between the two surfaces of the epithelium. The large scale of the isolation procedure makes it an appropriate starting point for purification of specific basal lateral membrane components.
LINE SWITCHING INSTALLATION FOR THE DRIVE OF THE TRANSRAPID 06 (1981)

The drive of the vehicle TRANSRAPID 06 is a synchronous long stator motor. The stator winding is divided into partitions which are fed with energy by two inverter groups by line cable. A line switching installation activates the single sections of the motor by the forward motion of the vehicle. The line switching logic controls and supervises the switching points. Vacuum interrupters realize the switching of sections.
Excitation dynamics of micro-structured atmospheric pressure plasma arrays (2010)

Abstract\nThe spatial dynamics of the optical emission from an array of 50 times 50 individual micro cavity plasma devices are investigated. The array is operated in argon and argon-neon mixtures close to atmospheric pressure with an AC voltage. The optical emission is analysed with phase and space resolution. It has been found that the emission is not continuous over the entire AC period, but occurs once per half period. Each of the observed emission phases shows a self-pulsing of the discharge, with several bursts of emission of fixed width and repetition rate. The number of emission bursts depends on applied voltage and frequency. Spatially resolved measurements prove that the emission bursts are formed by overlapping emission pulses from single discharge cavities. Intensity differences between positive and negative half-wave can be interpreted through spatially resolved measurements of single discharge cavities.
Thermally Stable Antireflective Coatings Based on Nanoporous Organosilicate Thin Films (2007)

Thermally stable nanoporous organosilicate thin films were realized by the microphase separation of pore-generating polymers mixed with an organosilicate matrix to be antireflective coatings (ARCs), for which a thin film with a refractive index (n) of 1.23 for zero reflection is required. The refractive index of such nanoporous organosilicate films can be tuned from 1.39 down to 1.23 by incorporating nanopores within the films. With a nanoporous single layer with n approximately 1.23, the light transmittance of the glass above 99.8% was achieved in the visible range (lambda approximately 550 nm). To overcome the limitation on the narrow wavelength for high transmittance imposed by a single antireflective nanoporous thin film, bilayer thin films with different refractive indices were prepared by placing a high refractive index layer with a refractive index of 1.45 below the nanoporous thin film. UV-vis transmittance of a glass coated with the bilayer films was compared with nanoporous single-layer films and it is demonstrated that the novel broadband antireflection coatings in a wide range of visible wavelength can be easily obtained by the organosilicate bilayer thin films described in this study. Also, ARCs developed in this study demonstrate excellent AR durability owing to the hydrophobic nature of the organosilicate matrix.
Ventilatory responses to hypercapnia and hypoxia in relatives of patients with the obesity hypoventilation syndrome (2000)

There is no evidence of impaired ventilatory chemoresponsiveness in first degree relatives of patients with OHS compared with age and BMI matched control subjects.
Space-charge trapping and conduction in LDPE, HDPE and XLPE (2001)

The mechanisms of charge injection, transport and trapping in low-density, high-density and cross-linked polyethylene (LDPE, HDPE and XLPE) are investigated in this paper through charging-discharging current measurements and space-charge observations. The conductivity of LDPE is much larger than that of XLPE and HDPE. The threshold for space-charge accumulation and that for a space-charge-limited current mechanism, coinciding for the same material, are almost identical for LDPE and HDPE, while the threshold of XLPE is higher. However, HDPE accumulates more charge than the other two materials. The depolarization space-charge turves and the conduction current versus field characteristics indicate that the mobility of LDPE is larger than that of XLPE and HDPE, which supports the significant difference in conductivity. The lower mobility, as well as the nature, depth and density of trap sites, can explain the difference in space-charge accumulation and thresholds.
Scalable NMR spectroscopy with semiconductor chips (2014)

State-of-the-art NMR spectrometers using superconducting magnets have enabled, with their ultrafine spectral resolution, the determination of the structure of large molecules such as proteins, which is one of the most profound applications of modern NMR spectroscopy. Many chemical and biotechnological applications, however, involve only small-to-medium size molecules, for which the ultrafine resolution of the bulky, expensive, and high-maintenance NMR spectrometers is not required. For these applications, there is a critical need for portable, affordable, and low-maintenance NMR spectrometers to enable in-field, on-demand, or online applications (e.g., quality control, chemical reaction monitoring) and co-use of NMR with other analytical methods (e.g., chromatography, electrophoresis). As a critical step toward NMR spectrometer miniaturization, small permanent magnets with high field homogeneity have been developed. In contrast, NMR spectrometer electronics capable of modern multidimensional spectroscopy have thus far remained bulky. Complementing the magnet miniaturization, here we integrate the NMR spectrometer electronics into 4-mm(2) silicon chips. Furthermore, we perform various multidimensional NMR spectroscopies by operating these spectrometer electronics chips together with a compact permanent magnet. This combination of the spectrometer-electronics-on-a-chip with a permanent magnet represents a useful step toward miniaturization of the overall NMR spectrometer into a portable platform.
Inhibition sites in F1-ATPase from bovine heart mitochondria (2005)

High-resolution crystallographic studies of a number of inhibited forms of bovine F1-ATPase have identified four independent types of inhibitory site: the catalytic site, the aurovertin B-binding site, the efrapeptin-binding site and the site to which the natural inhibitor protein IF1 binds. Hitherto, the binding sites for other inhibitors, such as polyphenolic phytochemicals, non-peptidyl lipophilic cations and amphiphilic peptides, have remained undefined. By employing multiple inhibition analysis, we have identified the binding sites for these compounds. Several of them bind to the known inhibitory sites. The amphiphilic peptides melittin and synthetic analogues of the mitochondrial import pre-sequence of yeast cytochrome oxidase subunit IV appear to mimic the natural inhibitor protein, and the polyphenolic phytochemical inhibitors resveratrol and piceatannol compete for the aurovertin B-binding site (or sites). The non-peptidyl lipophilic cation rhodamine 6G acts at a separate unidentified site, indicating that there are at least five inhibitory sites in the F1-ATPase. Each of the above inhibitors has significantly different activity against the bacterial Bacillus PS3 alpha3beta3gamma subcomplex compared with that observed with bovine F1-ATPase. IF1 does not inhibit the bacterial enzyme, even in the absence of the epsilon-subunit. An understanding of these inhibitors may enable rational development of therapeutic agents to act as novel antibiotics against bacterial ATP synthases or for the treatment of several disorders linked to the regulation of the ATP synthase, including ischaemia-reperfusion injury and some cancers.
Supplementary Figure S6 from Maltotriose Conjugation to a Chlorin Derivative Enhances the Antitumor Effects of Photodynamic Therapy in Peritoneal Dissemination of Pancreatic Cancer (2023)

&lt;p&gt;Correlation between the fluorescence intensities and the dose of Mal3-chlorin or the number of cells.&lt;/p&gt;
A comparison of sound localisation techniques using cross-correlation and spiking neural networks for mobile robotics (2011)

This paper outlines the development of a cross-correlation algorithm and a spiking neural network (SNN) for sound localisation based on real sound recorded in a noisy and dynamic environment by a mobile robot. The SNN architecture aims to simulate the sound localisation ability of the mammalian auditory pathways by exploiting the binaural cue of interaural time difference (ITD). The medial superior olive was the inspiration for the SNN architecture which required the integration of an encoding layer which produced biologically realistic spike trains, a model of the bushy cells found in the cochlear nucleus and a supervised learning algorithm. The experimental results demonstrate that biologically inspired sound localisation achieved using a SNN can compare favourably to the more classical technique of cross-correlation.
Studies on the physiology of bolting and flowering in Raphanus sativus L. II Annual rhythm in readiness to flower in Japanese radish, cultivar ‘Wase-shijunichi’ (1976)

Journal Article Studies on the physiology of bolting and flowering in Raphanus sativus L. II Annual rhythm in readiness to flower in Japanese radish, cultivar ‘Wase-shijunichi’ Get access Keun Chang Yoo, Keun Chang Yoo Horticultural Laboratory, Faculty of Agriculture, Kyushu UniversityFukuoka 820, Japan Search for other works by this author on: Oxford Academic Google Scholar Shunpei Uemoto Shunpei Uemoto Horticultural Laboratory, Faculty of Agriculture, Kyushu UniversityFukuoka 820, Japan Search for other works by this author on: Oxford Academic Google Scholar Plant and Cell Physiology, Volume 17, Issue 4, August 1976, Pages 863–865, https://doi.org/10.1093/oxfordjournals.pcp.a075345 Published: 01 August 1976 Article history Received: 25 November 1975 Published: 01 August 1976
Cardiac angiotensin II type I and type II receptors are increased in rats submitted to experimental hypothyroidism (2007)

This study assessed the behaviour of angiotensin II (Ang II) receptors in an experimental hypothyroidism model in male Wistar rats. Animals were subjected to thyroidectomy and resting for 14 days. The alteration of cardiac mass was evaluated by total heart weight (HW), right ventricle weight (RVW), left ventricle weight (LVW), ratio of HW, RVW and LVW to body weight (BW) and atrial natriuretic factor (ANF) expression. Cardiac and plasma Ang II levels and serum T3 and T4 were determined. The mRNA and protein levels of Ang II receptors were investigated by RT-PCR and Western blotting, respectively. Functional analyses were performed using binding assays. T3 and T4 levels and the haemodynamic parameters confirmed the hypothyroid state. HW/BW, RVW/BW and LVW/BW ratios and the ANF expression were lower than those of control animals. No change was observed in cardiac or plasma Ang II levels. Both AT1/AT2 mRNA and protein levels were increased in the heart of hypothyroid animals due to a significant increase of these receptors in the RV. Experiments performed in cardiomyocytes showed a direct effect promoted by low thyroid hormone levels upon AT1 and AT2 receptors, discarding possible influence of haemodynamic parameters. Functional assays showed that both receptors are able to bind Ang II. Herein, we have identified, for the first time, a close and direct relation of elevated Ang II receptor levels in hypothyroidism. Whether the increase in these receptors in hypothyroidism is an alternative mechanism to compensate the atrophic state of heart or whether it may represent a potential means to the progression of heart failure remains unknown.
Fundamental Properties and Optimal Gains of a Steady-State Velocity Measured &lt;i&gt;α&lt;/i&gt;-&lt;i&gt;β&lt;/i&gt; Tracking Filter (2014)

This paper clarifies the steady-state properties and performance of an α-β filter for moving target tracking using both position and velocity measurements. We call this filter velocity measured α-β (VM-α-β) filter. We first derive the stability condition and steady-state predicted errors as fundamental properties of the VM-α-β filter. The optimal gains for representative motion models are then derived from the Kalman filter equations. Theoretical and numerical analyses verify that VM-α-β filters with these optimal gains realize more accurate tracking than conventional α-β filters when the filter gains are relatively large. Our study reveals the conditions under which the predicted errors of the VM-α-β filters are less than those of conventional α-β filters. Moreover, numerical simulations clarify that the variance of the tracking error of the VM-α-β filters is approximately 3/4 of that of the conventional α-β filters in realistic situations, even when the accuracy of the position/velocity measurements is the same.
EXTERNAL QUALITY MEASUREMENTS REVEAL INTERNAL PROCESSES (2003)

With the present developments in CA technology it becomes possible to fine tune the storage conditions to the specific needs of the product. This generates the need to know the exact quality conditions of the product before storage starts. By measuring the initial quality we can determine these conditions optimally. At present the most likely candidates to assess the initial quality with fast and non-destructive measurements are colour, chlorophyll fluorescence, and maybe NIR spectroscopy. Two examples are presented where initial colour measurements on all products in a batch can be shown to be indicative for the keeping quality of that batch. The first example focuses on how initial colour measurements using a 3CCD video camera can be utilised to predict the keeping quality of a batch of cucumbers where colour itself is regarded as the most important quality attribute. The second example focuses on how colour measurements can be used to predict the keeping quality of a batch of strawberries where the ability to suppress a Botrytis cinerea infection is the most important quality attribute. Furthermore, attention is given to the use of modulated chlorophyll fluorescence imaging as a possible initial quality indicator for rose leafy stem cuttings. The level of inhomogeneity in the quantum yield of photochmistry od PSII of leaves of rose cuttings may be an indictor of the capability of the cutting to recover from severance, and to form roots and generate regrowth
System Issues and Tradeoffs Associated with Syngas Production and Combustion (2008)

The purpose of this article is to provide an overview of the basic technology of coal gasification for the production of syngas and the utilization of that syngas in power generation. The common gasifier types, fixed/moving bed, fluidized bed, entrained flow, and transport, are described, and accompanying typical product syngas compositions are shown for different coal ranks. Substantial variation in product gas composition is observed with changes in gasifier and coal feed type. Fuel contaminants such as sulfur, nitrogen, ash, as well as heavy metals such as mercury, arsenic, and selenium, can be removed to protect the environment and downstream processes. A variety of methods for syngas utilization for power production are discussed, including both present (gas turbine and internal combustion engines) and future technologies, including oxy-fuel, chemical looping, fuel cells, and hybrids. Goals to improve system efficiencies, further reduce NOx emissions, and provide options for CO2 sequestration require advancements in many aspects of IGCC plants, including the combustion system. Areas for improvements in combustion technology that could minimize these tradeoffs between cost, complexity, and performance are discussed.