gebhart/patrepeval huggingface dataset:
Fabrication of large-area metal nanoparticle arrays by nanosphere lithography for localized surface plasmon resonance biosensors (2011)

The localized surface plasmon resonance (LSPR) phenomenon that is characteristic of gold and silver nanoparticles has applications in areas such as portable and remote chemical and biological sensing. However, fabrication of metal nanoparticle arrays with high uniformity and repeatability, at a reasonable cost, is difficult. Nanosphere lithography (NSL) has been used to produce inexpensive nanoparticle arrays, through the use of monolayers of self-assembled microspheres as a deposition mask. However, lack of control over the location and size of the arrays, as well as poor uniformity over large areas, limits its use to research purposes. Here, we present large-area fabrication of nanoparticle arrays through both convective self-assembly NSL (CSANSL) and our new method, geometrically confined NSL (GCNSL). In GCNSL, microsphere assembly is confined to geometric patterns defined in photoresist. We show that 400nm polystyrene microspheres can be assembled inside of large arrays of photoresist trenches from 4-20μm in width and 500μm in length, with high uniformity, repeatability, and quality. Compared to CSANSL, GCNSL allows precise patterning of nanoparticle arrays for use in practical LSPR sensing devices, while still remaining inexpensive.
Over-expression of fibroblast growth factor receptor 3 in human hepatocellular carcinoma (2005)

Over-expression of FGFR3 may play an important role in liver carcinogenesis. FGFR3 may be an ideal candidate as a molecular marker in the diagnosis of HCC and a potential therapeutic target.
Product code optimization for determinate state LDPC decoding in robust image transmission (2006)

We propose a novel scheme for error-resilient image transmission. The proposed scheme employs a product coder consisting of low-density parity check (LDPC) codes and Reed-Solomon codes in order to deal effectively with bit errors. The efficiency of the proposed scheme is based on the exploitation of determinate symbols in Tanner graph decoding of LDPC codes and a novel product code optimization technique based on error estimation. Experimental evaluation demonstrates the superiority of the proposed system in comparison to recent state-of-the-art techniques for image transmission.
[Screening of Bacillus proteases with plasmin and activator types of action on fibrin]. (1991)

Forty cultures of aerobic sporogenic bacteria were screened for the plasmin and activator action of bacillar proteases on fibrin. The microorganisms were grown in chemically defined and complex potato-peptone media. Some active cultures were found to produce enzymes with both plasmin and activator types of action. The following organisms exerted the highest activity of the plasmin type; Bacillus macerans PI, strain P3, B. licheniformis 125 and B. firmus. The most active enzymes with the activator type of action were produced by B. macerans PI, Bacillus sp. 21P-7-1, strain 21P-7-2 and B. licheniformis 125.
Time-Resolved Interventional Cardiac C-arm Cone-Beam CT: An Application of the PICCS Algorithm (2011)

Time-resolved cardiac imaging is particularly interesting in the interventional setting since it would provide both image guidance for accurate procedural planning and cardiac functional evaluations directly in the operating room. Imaging the heart in vivo using a slowly rotating C-arm system is extremely challenging due to the limitations of the data acquisition system and the high temporal resolution required to avoid motion artifacts. In this paper, a data acquisition scheme and an image reconstruction method are proposed to achieve time-resolved cardiac cone-beam computed tomography imaging with isotropic spatial resolution and high temporal resolution using a slowly rotating C-arm system. The data are acquired within 14 s using a single gantry rotation with a short scan angular range. The enabling image reconstruction method is the prior image constrained compressed sensing (PICCS) algorithm. The prior image is reconstructed from data acquired over all cardiac phases. Each cardiac phase is then reconstructed from the retrospectively gated cardiac data using the PICCS algorithm. To validate the method, several studies were performed. Both numerical simulations using a hybrid motion phantom with static background anatomy as well as physical phantom studies have been used to demonstrate that the proposed method enables accurate reconstruction of image objects with a high isotropic spatial resolution. A canine animal model scanned in vivo was used to further validate the method.
Nitration Studies. XIV. Effects of Peroxides, Ultraviolet Irradiation, and Silent Electric Discharge in the Vapor Phase Nitration of Hydrocarbons1 (1961)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNitration Studies. XIV. Effects of Peroxides, Ultraviolet Irradiation, and Silent Electric Discharge in the Vapor Phase Nitration of Hydrocarbons1G. BRYANT BACHMAN and NORMAN W. STANDISHCite this: J. Org. Chem. 1961, 26, 2, 570–574Publication Date (Print):February 1, 1961Publication History Published online1 May 2002Published inissue 1 February 1961https://pubs.acs.org/doi/10.1021/jo01061a069https://doi.org/10.1021/jo01061a069research-articleACS PublicationsRequest reuse permissionsArticle Views77Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Three Dimensional Solution of Internal Flows using a Cell Vertex Finite Volume Method (1992)

Abstract : The numerical solutions of internal three dimensional Euler flows have been obtained, using a cell vertex finite volume method. The solver which has been developed, has been applied to a wide range of subsonic, transonic and supersonic test cases among which are the Ni-bump channel, the supersonic wedge cascade and the Squire and Winter 90 deg bend channel. A second order accurate, one step Lax-Wendroff scheme has been used to solve the unsteady equations, discretized in strong conservation form. Characteristic boundary conditions have been used along with appropriate artificial viscosity and smoothing models. The results illustrate the established flow symmetry in a subsonic Ni-bump channel, the shock - boundary interaction in transonic and supersonic Ni-channels and wedge cascade and finally, the secondary flow within a 90 deg bend channel. Despite the wide range in the Mach number and the diversity of flow geometries which have been tested, close agreement have been obtained with available analytical and numerical results associated with these test cases.
P3651Risk of death and cardiovascular events among patients presenting with acute coronary syndrome: the evolving role of cystatin C, NGAL and galectin-3 as prognostic biomarkers (2017)

with Lx-PAD(+)/CAS(-), 122 (17%) patients with Lx-PAD(-)/CAS(+), and 514 patients with CAD alone. There was significant deference in age (788 vs. 7511 vs. 7010 vs. 6512, p<0.001) and the prevalence of diabetes mellitus (61% vs. 52% vs. 41% vs. 35%, p<0.001) between these groups. In the coronary angiography, there were significant difference in disease severity between these groups (Figure During the median 4-year follow-up, there were 54 incidents of allcause death. Compared with the patients CAD alone, as a reference groups, patients with Lx-PAD(+)/CAS(+) and Lx-PAD(+)/CAS(-) had two to four-fold higher increase in the risk of death (hazard ratio [HR], 3.56; 95% confidence interval [CI], 1.68-7.27; p=0.001 and HR, 2.41; 95% CI, 1.06-5.12; p<0.05, respectively), whereas the presence of CAS does not increase the risk of death (Figure The freedom from all-cause death stratified across the presence or the absence of extra-cardiac disease is shown (Figure
Use of Traditional and Genetically Modified Probiotics in Human Health: What Does the Future Hold? (2018)

Advances in recombinant technology (e.g., genetic engineering) and in the understanding of the human immune system have led to prodigious advances in the development of novel delivery systems for mucosal administration (1 , 2). The administration of therapeutic molecules through mucosal routes offers several important advantages over conventional strategies (i.e., systemic injection) such as reduction of secondary effects, easy administration, and the possibility to modulate both systemic and mucosal immune responses (3). Moreover, it is important for molecules of health interest that exert their effects at mucosal surfaces, the gastrointestinal tract (GIT), for example, to be delivered directly to the appropriate site. Nonetheless, a major disadvantage of the mucosal route of administration is that the actual amount of protein to be administered needs to be large due to the very small quantities of protein that survive degradation at mucosal surfaces such as the GIT (1 , 3).
Online subscriptions with anonymous access (2008)

Online privacy is an increasingly important problem, as many services are now offered in a digital form. Privacy (or the lack thereof) is of a special concern in subscriptions to large data repositories with heterogeneous information, where the service provider can easily profile its users and sell that information to third parties. In this work we present the design and implementation of a system that closely resembles the current practice of subscriptions to many services such as newspapers, digital libraries, music collections, etc., but at the same time offers anonymous access to the service. As with current practice, in our solution a user subscribes to the service obtaining access to it for a certain period of time, at the end of which the subscription expires.
Escola de enfermagem da Universidade Federal de Minas Gerais: setenta anos de existência (2003)

The subject of this text is to show some events, happenings and aspects related to the history of the School of Nursing of the Federal University of Minas Gerais, that is celebrating its seventieth anniversary in 2003. It is divided in two large periods: one, from the creation of the school, in 1933, until 1968, and the other, from 1968 to the present days.
Modeling buffer layer IGBTs for circuit simulation (1995)

The dynamic behavior of commercially available buffer layer IGBTs is described. It is shown that buffer layer IGBTs become much faster at high voltages than nonbuffer layer IGBTs with similar low voltage characteristics. Because the fall times specified in manufacturers' data sheets do not reflect the voltage dependence of switching speed, a new method of selecting devices for different circuit applications is suggested. A buffer layer IGBT model is developed and implemented into the Saber circuit simulator, and a procedure is developed to extract the model parameters for buffer layer IGBTs. It is shown that the new buffer layer IGBT model can be used to describe the dynamic behavior and power dissipation of buffer layer IGBTs in user-defined application circuits. The results of the buffer layer IGBT model are verified using commercially available IGBTs.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
A Comprehensive and Modular Stochastic Modeling Framework for the Variability-Aware Assessment of Signal Integrity in High-Speed Links (2017)

This paper presents a comprehensive and modular modeling framework for stochastic signal integrity analysis of complex high-speed links. Such systems are typically composed of passive linear networks and nonlinear, usually active, devices. The key idea of the proposed contribution is to express the signals at the ports of each of such system elements or subnetworks as a polynomial chaos expansion. This allows one to compute, for each block, equivalent deterministic models describing the stochastic variations of the network voltages and currents. Such models are synthesized into SPICE-compatible circuit equivalents, which are readily connected together and simulated in standard circuit simulators. Only a single circuit simulation of such an equivalent network is required to compute the pertinent statistical information of the entire system, without the need of running a large number of time-consuming electromagnetic circuit cosimulations. The accuracy and efficiency of the proposed approach, which is applicable to a large class of complex circuits, are verified by performing signal integrity investigations of two interconnect examples.
Stabilization of Oil-in-Water Emulsions by Colloidal Particles Modified with Short Amphiphiles (2008)

Emulsions stabilized through the adsorption of colloidal particles at the liquid-liquid interface have long been used and investigated in a number of different applications. The interfacial adsorption of particles can be induced by adjusting the particle wetting behavior in the liquid media. Here, we report a new approach to prepare stable oil-in-water emulsions by tailoring the wetting behavior of colloidal particles in water using short amphiphilic molecules. We illustrate the method using hydrophilic metal oxide particles initially dispersed in the aqueous phase. The wettability of such particles in water is reduced by an in situ surface hydrophobization that induces particle adsorption at oil-water interfaces. We evaluate the conditions required for particle adsorption at the liquid-liquid interface and discuss the effect of the emulsion initial composition on the final microstructure of oil-water mixtures containing high concentrations of alumina particles modified with short carboxylic acids. This new approach for emulsion preparation can be easily applied to a variety of other metal oxide particles.
Computer-interfaced digital counter-analogue data acquisition system and demonstration of signal-to-noise enhancement methods (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTComputer-interfaced digital counter-analogue data acquisition system and demonstration of signal-to-noise enhancement methodsQing Xu , J. N. Demas , and Marvin Grubb Cite this: J. Chem. Educ. 1989, 66, 8, A199Publication Date (Print):August 1, 1989Publication History Received3 August 2009Published online1 August 1989Published inissue 1 August 1989https://doi.org/10.1021/ed066pA199Request reuse permissionsArticle Views64Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (3 MB) Get e-Alertsclose Get e-Alerts
Scintillation of Light from Distant Objects due to Anisotropic and Non-Kolmogorov Turbulence (2013)

Abstract : Observations at AMOS and elsewhere suggest that turbulence is sometimes non-isotropic and non-Kolmogorov in nature. Such turbulence can produce different jitter, wavefront error, and scintillation than expected from isotropic Kolmogorov turbulence. These differences can impact the design of sensor systems that must see through this atypical turbulence. Quantitative definitions are provided for anisotropic turbulence and non-Kolmogorov turbulence. Using previously developed analyses and with extensive simulations for a plane wave, corresponding to light from a satellite or star, results are presented that parametrically show how scintillation differs from that of standard Kolmogorov turbulence, under a variety of conditions. Also included are conditions appropriate for observations of sources on Mauna Loa as seen at AMOS.
Ophthalmoscopic findings in subacute sclerosing panencephalitis. (1973)

4. Deter-ioration of reading skills and school performance 5. Oedema of the optic disc (papilloedema or papillitis) 6. Optic atrophy or temporal pallor 7. Nystagmus or other abnormal ocular movrements 8.
Developing a Mobile App for Young Adults with Nonsuicidal Self-Injury: A Prototype Feedback Study (2022)

Nonsuicidal self-injury (NSSI) affects approximately 13% of young adults. Though evidence-based treatments for NSSI exist, most young adults do not receive treatment. Digital interventions can provide access to evidence-based treatments for NSSI at scale. Further, preliminary research suggests the acceptability, feasibility, and potential efficacy of digital interventions for NSSI. To date, however, there are few publicly available digital interventions developed specifically for young adults who engage in NSSI. The aim of this study was to solicit young adults' impressions of early app prototypes to identify ways of improving interactive features and content needs. Building on a prior interview study which explored young adults' self-management of NSSI and their use of technology in self-management, this study involved three waves of iterative app prototype feedback sessions with 10 young adults with past month NSSI. In general, participants responded favorably and provided feedback to augment the app to better meet their needs, including adding new features and functionality as well as increasing opportunities for personalization. We discuss two key design challenges related to the roles of tracking and temporality in digital interventions for NSSI, and then frame design considerations related to these challenges within the lived informatics model.
Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 2nd – 4th, 2021, Italy) (2022)

Advances in immune checkpoint and combination therapy have led to improvement in overall survival for patients with advanced melanoma. Improved understanding of the tumor, tumor microenvironment and tumor immune-evasion mechanisms has resulted in new approaches to targeting and harnessing the host immune response. Combination modalities with other immunotherapy agents, chemotherapy, radiotherapy, electrochemotherapy are also being explored to overcome resistance and to potentiate the immune response. In addition, novel approaches such as adoptive cell therapy, oncogenic viruses, vaccines and different strategies of drug administration including sequential, or combination treatment are being tested. Despite the progress in diagnosis of melanocytic lesions, correct classification of patients, selection of appropriate adjuvant and systemic theràapies, and prediction of response to therapy remain real challenges in melanoma. Improved understanding of the tumor microenvironment, tumor immunity and response to therapy has prompted extensive translational and clinical research in melanoma. There is a growing evidence that genomic and immune features of pre-treatment tumor biopsies may correlate with response in patients with melanoma and other cancers, but they have yet to be fully characterized and implemented clinically. Development of novel biomarker platforms may help to improve diagnostics and predictive accuracy for selection of patients for specific treatment. Overall, the future research efforts in melanoma therapeutics and translational research should focus on several aspects including: (a) developing robust biomarkers to predict efficacy of therapeutic modalities to guide clinical decision-making and optimize treatment regimens, (b) identifying mechanisms of therapeutic resistance to immune checkpoint inhibitors that are potentially actionable, (c) identifying biomarkers to predict therapy-induced adverse events, and (d) studying mechanism of actions of therapeutic agents and developing algorithms to optimize combination treatments. During the Melanoma Bridge meeting (December 2nd-4th, 2021, Naples, Italy) discussions focused on the currently approved systemic and local therapies for advanced melanoma and discussed novel biomarker strategies and advances in precision medicine as well as the impact of COVID-19 pandemic on management of melanoma patients.
Wrapping cytochrome c around single-wall carbon nanotube: engineered nanohybrid building blocks for infrared detection at high quantum efficiency (2015)

Biomolecule cytochrome c (Cty c), a small molecule of a chain of amino acids with extraordinary electron transport, was helically wrapped around a semiconductive single-wall carbon nanotube (s-SWCNT) to form a molecular building block for uncooled infrared detection with two uniquely designed functionalities: exciton dissociation to free charge carriers at the heterojunction formed on the s-SWCNT/Cty c interface and charge transport along the electron conducting chain of Cty c (acceptor) and hole conducting channel through s-SWCNT (donor). Such a design aims at addressing the long-standing challenges in exciton dissociation and charge transport in an SWCNT network, which have bottlenecked development of photonic SWCNT-based infrared detectors. Using these building blocks, uncooled s-SWCNT/Cyt c thin film infrared detectors were synthesized and shown to have extraordinary photoresponsivity up to 0.77 A W(-1) due to a high external quantum efficiency (EQE) in exceeding 90%, which represents a more than two orders of magnitude enhancement than the best previously reported on CNT-based infrared detectors with EQE of only 1.72%. From a broad perspective, this work on novel s-SWCNT/Cyt c nanohybrid infrared detectors has developed a successful platform of engineered carbon nanotube/biomolecule building blocks with superior properties for optoelectronic applications.