gebhart/patrepeval huggingface dataset:
Cytokine Release Ensuing Interaction Between Human Peripheral Blood Mononuclears and Epstein-Barr Virus Transformed B-CLL Cell Line (2020)

The noticeable increased production of inflammatory cytokines by PBMC following direct contact with EHEB cells and to a lesser degree with their supernatants implies the existence of an immune dialogue between these two types of cells. The results support the concept that not only leukemic cells, but also peripheral blood mononuclears could serve as a therapeutic target for B-CLL.
Fruit‐pollen‐latex cross‐reactivity: implication of profilin (Bet v 2) (1999)

Patients with allergy to plant-derived food and associated pollinosis showed a high frequency of IgE reactivity to Bet v 2, which may cause positive serum IgE determinations to latex and birch pollen due to the presence of cross-reactive epitopes. IgE reactivity to Bet v 2 may serve as an indicator of broad sensitization.
Determinationof the Thermoregulatory Specifications for Thermal Manikins (2011)

Triad person-clothing-environments set specific requirements in the development and optimization of products in the field of personal protective equipment that integrates into the transportation, living and working environments. The optimal balance in the triad as well the effectiveness of its relationship depends on the clothing, environments to which workers are exposed while performing their activities and on their performance. The aim of the present study was to determine the optimal combat clothing ensembles conducting hikes and guard duty during winter and summer months. During the trials, the subjects were instrumented to obtain skin and core temperatures, clothing microenvironment temperatures and humidity, as well as oxygen uptake and heart rate. In addition to providing data regarding thermal and evaporative resistances, the manikins also provided data for a numerical model of human temperature regulation, which was used to simulate the field trials. According to the given facts the relationship discussed in the paper is man-clothing-environment triad in terms of thermal comfort, requirements for the simulation of thermoregulation and the use of heat manikin.
Integration of cardiac and respiratory motion into MRI roadmaps fused with x‐ray (2013)

A method has been presented for creating dynamic 3D roadmaps that incorporate cardiac and respiratory motion. These roadmaps can be overlaid on live X-ray fluoroscopy to enhance image guidance for cardiac interventions.
Staticization and Associated Hamilton-Jacobi and Riccati Equations (2015)

The use of stationary-action formulations for dynamical systems allows one to generate fundamental solutions for classes of two-point boundary-value problems (TPBVPs). One solves for stationary points of the payoff as a function of inputs, a task which is significantly different from that in optimal control problems. Both a dynamic programming principle (DPP) and a Hamilton-Jacobi partial differential equation (HJ PDE) are obtained for a class of problems subsuming the stationary-action formulation. Although convexity (or concavity) of the payoff may be lost as one propagates forward, stationary points continue to exist, and one must be able to use the DPP and/or HJ PDE to solve forward to such time horizons. In linear/quadratic models, this leads to a requirement for propagation of solutions of differential Riccati equations past finite escape times. Such propagation is also required in (nonlinear) n-body problem formulations where the potential is represented via semiconvex duality.
Heterocycles, XXIV. Synthesis of Optically Pure 2,3-trans-5,7,3,4,5-Pentahydroxyflavan-3,4-diols and Comparison With Naturally Occurring Leucodelphinidis (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHeterocycles, XXIV. Synthesis of Optically Pure 2,3-trans-5,7,3,4,5-Pentahydroxyflavan-3,4-diols and Comparison With Naturally Occurring LeucodelphinidisMasayuki Onda, Shaoshun Li, Xian Li, Yoshihiro Harigaya, Hiroshi Takahashi, Hiromi Kawase, and Hitoshi KagawaCite this: J. Nat. Prod. 1989, 52, 5, 1100–1106Publication Date (Print):September 1, 1989Publication History Published online1 July 2004Published inissue 1 September 1989https://pubs.acs.org/doi/10.1021/np50065a029https://doi.org/10.1021/np50065a029research-articleACS PublicationsRequest reuse permissionsArticle Views328Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Investigation of pulsed non-melt laser annealing (NLA) of CIGS-based solar cells (2003)

Pulsed non-melt laser annealing (NLA) has been used to modify the near surface defect and related junction properties in the ClGS solar cells. CIGS films deposited on Mo/glass substrates were annealed by using a 248 nm line Kr excimer laser at selected laser energy densities and pulse number, and characterized by the dual beam optical modulation (DBOM), XRD, SEM, and Hall effect measurements. In addition, selected annealed CdS/CIGS films processed by NLA were fabricated into cells, and characterized by the photo I-V and Q-E measurements. The results suggest that low power (P/sub L/ < 50 mJ/cm/sup 2/) NLA treatment could increase the effective carrier lifetime, mobility, film grain size, and sheet resistance and lower the near-surface defect density in the films, thus improve the performance of CIGS cells.
Android Robot SAYA (2014)

This paper introduces the android robot SAYA and its applications. SAYA was developed to enable human beings and robots to communicate emotions. SAYA shows six basic facial expressions: surprise, fear, disgust, anger, sadness, and happiness. In order to improve the quality of facial expressions and its reality, the android robot which mimics a real human being was also developed. The suggested practical applications for SAYA are a receptionist and a remote teacher. The android robot SAYA is also serving as a simulated patient for medical interview training in psychiatric education.
OBSERVATIONS ON THE DYNAMICS OF THE BLADDER NECK 1 (1966)

SUMMARY
Protein synthesis, myosin ATPase activity and myofibrillar protein composition in hearts from tumour-bearing rats and mice (1989)

Growing rats and adult weight-stable mice bearing a transplantable methylcholanthrene-induced sarcoma were compared with animals with various states of malnutrition. Heart protein synthesis was measured in vivo. Myocardial RNA, myofibrillar protein composition and the Ca2+-activated ATPase activity in heavy chains of native myosin were measured. 'Fingerprints' were made from myosin by trypsin treatment to evaluate possible structural changes in the protein. Cardiac protein-synthesis rate was decreased by 20% in growing tumour-bearing rats, by 35% in protein-malnourished (rats) and by 47% in starved rats, compared with freely fed controls (P less than 0.05). Adult tumour-bearing mice showed no significant decrease in myocardial protein synthesis. Pair-weighed control mice had significantly depressed heart protein synthesis. Protein translational efficiency was maintained in both tumour-bearing rats and mice, but was decreased in several groups of malnourished control animals. The Ca2+-activated myosin ATPase activity was decreased in all groups of malnourished animals, including tumour-bearing mice and rats, without any evidence of a change in cardiac isomyosin composition. We conclude that loss of cardiac muscle mass in tumour disease is communicated by both depressed synthesis and increased degradation largely owing to anorexia and host malnutrition. Increased adrenergic sensitivity in hearts from tumour-bearing and malnourished animals is not communicated by increased Ca2+-activated ATPase activity. This may be down-regulated in all groups with malnutrition, without any observable alterations in the isomyosin profile.
Packet video for heterogeneous networks using CU-SeeMe (2002)

Software based desktop videoconferencing tools are developed to demonstrate techniques necessary for video delivery in heterogeneous packet networks. Pyramidal compression, congestion avoidance, end-to-end delivery, and predictive rate control results are presented.
Microlensig Binaries with Candidate Brown Dwarf Companions:The Astrophysical Journal (2012)

Brown dwarfs are important objects because they may provide a missing link between stars and planets, two populations that have dramatically different formation history. In this paper, we present the candidate binaries with brown dwarf companions that are found by analyzing binary microlensing events discovered during 2004 - 2011 observation seasons. Based on the low mass ratio criterion of q &lt;0.2, we found 7 candidate events, including OGLE-2004-BLG-035, OGLE-2004-BLG-039, OGLE-2007-BLG-006, OGLE-2007-BLG-399/MOA-2007-BLG-334, MOA-2011-BLG-104/OGLE-2011-BLG-0172, MOA-2011-BLG-149, and MOA-201-BLG-278/OGLE-2011-BLG-012N. Among them, we are able to confirm that the companions of the lenses of MOA-2011-BLG-104/OGLE-2011-BLG-0172 and MOA-2011-BLG-149 are brown dwarfs by determining the mass of the lens based on the simultaneous measurement of the Einstein radius and the lens parallax. The measured mass of the brown dwarf companions are (0.02 +/- 0.01) M_Sun and (0.019 +/- 0.002) M_Sun for MOA-2011-BLG-104/OGLE-2011-BLG-0172 and MOA-2011-BLG-149, respectively, and both companions are orbiting low mass M dwarf host stars. More microlensing brown dwarfs are expected to be detected as the number of lensing events with well covered light curves increases with new generation searches.
The use of effect sizes to characterize the nature of cognitive change in psychopharmacological studies: an example with scopolamine (2008)

Drug induced cognitive change is generally investigated using small sample sizes. In terms of null hypothesis significance testing (NHST) this can render a meaningful change non-significant, as a result of insufficient power in the statistical model. NHST leads to 'all or none' thinking, where a non-significant result is interpreted as an absence of change. An effect size calculation indicates the magnitude of change which has occurred post-intervention, and therefore whether a significant result is meaningful. We used a scopolamine challenge to demonstrate the usefulness of effect sizes. The aim of the study was to determine how effect sizes could describe the cognitive changes that occur following administration of subcutaneous scopolamine (s.c. scopolamine). Twenty four healthy young males (M = 32.6, sd = 4.5 years) were administered placebo and 0.2 mg, 0.4 mg & 0.6 mg of s.c. scopolamine using a 4-way crossover design. Memory, learning, psychomotor function, attention and executive function were assessed. Scopolamine significantly impaired performance on all tasks in a dose and time related manner. These results demonstrate the functionality of change scores to draw comparisons between different times and doses. This methodology overcomes the limitations of comparisons between studies using different tasks, doses and time at which cognitive functions are measured.
Engineered Cytochrome P450-Catalyzed Oxidative Biaryl Coupling Reaction Provides a Scalable Entry into Arylomycin Antibiotics (2022)

We report herein the first example of a cytochrome P450-catalyzed oxidative carbon-carbon coupling process for a scalable entry into arylomycin antibiotic cores. Starting from wild-type hydroxylating cytochrome P450 enzymes and engineered <i>Escherichia coli</i>, a combination of enzyme engineering, random mutagenesis, and optimization of reaction conditions generated a P450 variant that affords the desired arylomycin core <b>2d</b> in 84% assay yield. Furthermore, this process was demonstrated as a viable route for the production of the arylomycin antibiotic core on the gram scale. Finally, this new entry affords a viable, scalable, and practical route for the synthesis of novel Gram-negative antibiotics.
Insecticidal and Acaricidal Activities of Domestic Plant Extracts against Five Major Arthropod Pests (2002)

Methanol extracts from 420 samples of 173 plant species in 58 families were tested at 5000 ppm for their insecticidal and acaricidal activities against five economically important arthropod pests by spray method. The responses varied with arthropod pest species, plant species and plant tissue sampled. In a test with Nilaparvata lugens Stal, extracts from Zanthoxylum piperitum barks, Chamaecyparis obtusa leaf and Quercus salicina leaf showed potent insecticidal activity. With Plutella xylostella L., potent larvicidal activity was observed from extracts of Platycarya strobilacea wood, Meliosma myriantha barks, Sophora japonica leaf, Zanthoxylum piperitum barks, and Pinus thunbergii wood. Methanol extracts of Sophora japonica leaf and Zanthoxylum piperitum barks showed high insecticidal activity against Spodoptera litura. In a test with Tetranychus urticae Koch, extract from Carpinus coreana leaf, Firmiana simplex barks, Elaeagnus macrophylla leaf, Aralia elata leaf, Comus controversa barks and Chamaecyparis obtusa leaf exhibited strong acaricidal activity. As a naturally occurring pest control agent, Zanthoxylum piperitum barks could be useful as new insecticidal and acaricidal products against various arthropod pests.
A metallocene catalyst system for olefin polymerization using a heteropolyacid as the counter‐anion (1995)

Abstract Polymerization of ethylene and propene were conducted with bis(cyclopentadienylzirconium dichloride) (Cp 2 ZrCl 2 ) and ethylenebis(1‐indenyl)zirconium dichloride (Et(Ind) 2 ZrCl 2 ) combined with trialkylaluminium compounds using heteropolyacids as the counter‐anions, giving linear polyethylene and isotactic polypropene, respectively. No polymer was obtained when using Cp 2 Zr(CH 3 ) 2 instead of Cp 2 ZrCl 2 . The mechanism of the formation of active species is briefly discussed on the basis of these results.
Automated Homogeneous Immunoassay Analysis of Cotinine in Urine (2002)

A study was conducted to evaluate the performance comparison of a homogeneous enzyme immunoassay (EIA) designed to detect cotinine in urine and carbon monoxide (CO) breath measurements to determine smoking status. The clinical comparison was done using urine and breath specimens from 218 volunteers. Urine samples were analyzed by immunoassay and confirmed by gas chromatography-mass spectrometry (GC-MS). Breath carbon monoxide was determined by a commercial analyzer. Using cutoffs of 10 ppm for CO and 500 ng/mL for urinary cotinine, the relative sensitivity/specificity was 93.6%/74.0%. The positive predictive value was 86.8%, and the negative predictive value was 86.5%. However, comparison of the EIA to GC-MS showed a sensitivity/specificity of 96.2%/98.4% and a positive predictive value of 99.3%. The EIA was also evaluated non-clinically for precision, stability, recovery, and interferences. In addition, the non-clinical evaluation demonstrated coefficients of variation from 0.37 to 1.09% across cotinine concentrations ranging from 0 to 5000 ng/mL. The assay was found to be highly specific for cotinine and cross-reacted to a limited degree with 3-hydroxycotinine. Finally, multiple freeze-thaw cycles of urines containing cotinine showed no degradation of the drug in the specimen when tested in the EIA. Thus, the EIA tested is a rapid, lab-based test that can reliably determine cotinine levels and their relation to smoking status.
Characterization of New Races of Xanthomonas oryzae pv. oryzae in Mali Informs Resistance Gene Deployment (2019)

Bacterial leaf blight caused by <i>Xanthomonas oryzae</i> pv. <i>oryzae</i> represents a severe threat to rice cultivation in Mali. Characterizing the pathotypic diversity of bacterial populations is key to the management of pathogen-resistant varieties. Forty-one <i>X. oryzae</i> pv. <i>oryzae</i> isolates were collected between 2010 and 2013 in the major rice growing regions in Mali. All isolates were virulent on the susceptible rice variety Azucena; evaluation of the isolates on 12 near isogenic rice lines, each carrying a single resistance gene, identified six new races (A4 to A9) and confirmed race A3 that was previously reported in Mali. Races A5 and A6, isolated in Office du Niger and Sélingué, were the most prevalent races in Mali. Race A9 was the most virulent, circumventing all of the resistance genes tested. Xa3 controlled six of seven races (i.e., 89% of the isolates tested). The expansion of race A9 represents a major risk to rice cultivation and highlights the urgent need to identify a local source of resistance. We selected 14 isolates of <i>X. oryzae</i> pv. <i>oryzae</i> representative of the most prevalent races to evaluate 29 rice varieties grown by farmers in Mali. Six isolates showed a high level of resistance to <i>X. oryzae</i> pv. <i>oryzae</i> and were then screened with a larger collection of isolates. Based on the interactions among the six varieties and the <i>X. oryzae</i> pv. <i>oryzae</i> isolates, we characterized eight different pathotypes (P1 to P8). Two rice varieties, SK20-28 and Gigante, effectively controlled all of the isolates tested. The low association observed among races and pathotypes of <i>X. oryzae</i> pv. <i>oryzae</i> suggests that the resistance observed in the local rice varieties does not simply rely on single known <i>Xa</i> genes. <i>X. oryzae</i> pv. <i>oryzae</i> is pathogenically and geographically diverse. Both the races of <i>X. oryzae</i> pv. <i>oryzae</i> characterized in this study and the identification of sources of resistance in local rice varieties provide useful information to inform the design of effective breeding programs for resistance to bacterial leaf blight in Mali.
Route Recommendations for Intelligent Transportation Services (2019)

The accumulated large amount of mobility data and the ability to track moving people or objects have enabled us to develop advanced mobile recommendations, which are essential to recommend a sequence of locations to an individual user on the move. In this paper, we study a particular case of mobile recommendations, route recommendations to drivers, by utilizing vehicle GPS data. Specifically, we formulate a new Route Recommendation with Relaxed Assumptions (RR-RA) problem, the goal of which is to recommend a sequence of locations to a driver based on his current location in order to maximize his business success. To make our recommendation practical and scalable for real practice, we need to produce recommendation results in a timely fashion once a request emerges. Therefore, we propose an efficient algorithm to efficiently generate recommendations. Furthermore, we identify and address a destination-oriented route recommendation (DORR) problem. Without solving DORR problem, RR-RA alone does not work well in practice because drivers may encounter the destination constraint on a daily basis. We develop a dedicated and efficient algorithm for solving DORR problem. The package of solutions for both RR-RA and DORR problems provide a comprehensive approach for route recommendations to drivers. We evaluate our methods using both real-world GPS data and synthetic data, and demonstrate the effectiveness and efficiency of proposed methods with different evaluation metrics.
Development of a duplex PCR as screening tool for the detection of Crangon crangon bacilliform virus in the European brown shrimp Crangon crangon (2016)

The brown shrimp Crangon crangon is an important species ecologically and economically. Due to low landings of large animals (less than 2 % > 7cm) and a growing demand for living shrimps, C. crangon was identified as a candidate for aquaculture. However, in 2004, researchers found thatthis species could be infected with C. Crangon Bacilliform Virus, an intranuclear bacilliform virus mainly infecting the hepatopancreas. This virus,acting as an extra stress factor, could affect the health status of C. crangon reared in captivity, resulting in higher mortality. CCBV could therefore bethe reason why the life cycle of C. crangon was never closed in captivity. A screening tool for the detection of CCBV was developed in order toexamine the infection severity. The research focused on the optimization of a duplex PCR, which amplifies an internal amplification control geneand a viral gene. Once the duplex PCR was optimized with reared shrimp, a prevalence study was conducted with wild samples from several regionsof the Belgian Coast. Results indicate that the prevalence of CCBV is between 80 and 94 % in the examined populations. The high prevalence canindicate that the virus is transmitted from female to offspring. To confirm this hypothesis, more experiments are needed to determine how thisvirus is transmitted to the offspring. The development of a detection tool for CCBV offers the ability to rapidly and reliably screen wild and reared C.crangon and also transmission can be studied in more detail. This will enable us to select healthy and virus-free individuals, which will not onlycontribute to the rearing of this species, but also for research purposes, allowing us to use standardized bioassay tests.
Identification friend-or-foe (IFF) sensor uncertainties, ambiguities, deception and their application to the multi-source fusion process (2002)

The importance of quantifying and modeling sensor uncertainties associated with kinematic, attribute, and hybrid sensors and their effect on the data fusion process (Bayesian, Dempster-Shafer, etc.) has not been well described. This paper explores some of the characteristics and uncertainties associated with MK XII Identification Friend-or-Foe (IFF) including its limitations, inherent error sources, and robustness to jamming and interference. A general multi-source sensor fusion process is described using Non-Cooperative Target Recognition, electronic support measures and IFF dissimilar source inputs with specific attention placed on realizable IFF sensor systems and how they need to be characterized in order to understand and design an optimized and effective multi-source fusion process.
Functionalized α-cyclodextrins as potentiometric chiral sensors (1992)

Octylated cyclodextrins have been systhesized and characterized by mass spectrometry (+ fast atom bombardment, + field desorption) and 500 MHz 1H nuclear magnetic resonance spectroscopy. These highly lipophilic, enantiomerically pure molecules have been incorporated into solvent polymeric membranes and investigated as electrochemical sensors for chiral molecules incorporating aryl rings. Bis(1-butylpentyl) adipate (BBPA) and ortho-nitrophenyl octyl ether (o-NPOE) were used as plasticizers. Electrodes using BBPA as the plasticizer were stable and well defined with a limit of detection for ephedrine of –log[c]= 6.5. Interference from serum levels of Na+, K+ and Ca2+ is minimal; the best value obtained for –log kpot(the over-all selectivity coefficient) was 3.9 with BBPA as plasticizer and 1 × 10–3 mol dm–3 NH4Cl as inner filling solution. The electrodes were highly enantioselective in binding ephedrine (enantioselectivity kpot(+)/(–), 2.7). The o-NPOE-based electrodes, although enantioselective with minimal interference from serum levels of Na+, K+ and Ca2+, behaved in a time-dependent manner.