gebhart/patrepeval huggingface dataset:
Structure and optical properties of cadmium sulfide superclusters in zeolite hosts (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructure and optical properties of cadmium sulfide superclusters in zeolite hostsNorman Herron, Ying Wang, Mike M. Eddy, Galen D. Stucky, Dave E. Cox, Karin Moller, and Thomas BeinCite this: J. Am. Chem. Soc. 1989, 111, 2, 530–540Publication Date (Print):January 1, 1989Publication History Published online1 May 2002Published inissue 1 January 1989https://doi.org/10.1021/ja00184a021RIGHTS & PERMISSIONSArticle Views884Altmetric-Citations360LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (1 MB) Get e-Alerts Get e-Alerts
Integration of an ISFET with a porous microelectrode for application to protein characterization (2002)

This paper describes a way of dynamic buffer capacity measurement to characterize proteins, using a coulometric sensor-actuator system. The sensor-actuator is made by integrating an ISFET (ion-sensitive field effect transistor) with a porous microelectrode. Lysozyme and ribonuclease were studied. The results show that the buffer capacity of proteins is both a function of pH and their concentrations. The characters of studied proteins can be distinguished each other from measured curves.
Autonomous Parachute‐Based Precision Delivery Systems (2016)

Abstract Introduction of a ram‐air parafoil possessing the steering and rate‐of‐descent control authority sparked a great interest of using them for autonomous precision payload delivery. A technological revolution of 1990s enabled the usage of relatively inexpensive powerful computer and miniature sensors including Global Positioning System receiver as a part of airborne guidance unit, processing all available data and producing corrective commands in real time. This chapter presents the current state of the art in aerial precision payload delivery starting from the concept of operations and key performance requirements and continuing with an overview of a variety of different‐weight systems that were developed and fielded within the Joint Precision Airdrop System program led by the US Army and US Air Force. Compared to uncontrolled round parachutes, these systems allowed reducing a touchdown error by an order of magnitude. The chapter further describes key elements of modeling of controlled parachute systems and designing guidance, navigation, and control architecture for them. The chapter concludes with presenting some latest developments and cost‐effective alternatives involving traditional parachutes with added limited control authority.
Exceptionally Stable and Efficient Solid Supported Hoveyda-Type Catalyst (2015)

The ammonium tagged Hoveyda-type catalyst bearing sterically enlarged N-heterocyclic carbene ligand was synthesized and supported on SBA-15. The obtained heterogeneous olefin metathesis catalyst forms unprecedentedly stable Ru-methylidenes and provides products of ring-closing and cross metathesis with turnover numbers (TONs) up to 35 000 and turnover frequencies (TOFs) up to 1590 min–1. The catalyst proved to be truly recyclable and effective in a continuous flow mode.
Automatic Stem Mapping by Merging Several Terrestrial Laser Scans at the Feature and Decision Levels (2013)

Detailed up-to-date ground reference data have become increasingly important in quantitative forest inventories. Field reference data are conventionally collected at the sample plot level by means of manual measurements, which are both labor-intensive and time-consuming. In addition, the number of attributes collected from the tree stem is limited. More recently, terrestrial laser scanning (TLS), using both single-scan and multi-scan techniques, has proven to be a promising solution for efficient stem mapping at the plot level. In the single-scan method, the laser scanner is placed at the center of the plot, creating only one scan, and all trees are mapped from the single-scan point cloud. Consequently, the occlusion of stems increases as the range of the scanner increases, depending on the forest's attributes. In the conventional multi-scan method, several scans are made simultaneously inside and outside of the plot to collect point clouds representing all trees within the plot, and these scans are accurately co-registered by using artificial reference targets manually placed throughout the plot. The additional difficulty of applying the multi-scan method is due to the point-cloud registration of several scans not being fully automated yet. This paper proposes a multi-single-scan (MSS) method to map the sample plot. The method does not require artificial reference targets placed on the plot or point-level registration. The MSS method is based on the fully automated processing of each scan independently and on the merging of the stem positions automatically detected from multiple scans to accurately map the sample plot. The proposed MSS method was tested on five dense forest plots. The results show that the MSS method significantly improves the stem-detection accuracy compared with the single-scan approach and achieves a mapping accuracy similar to that achieved with the multi-scan method, without the need for the point-level registration.
Light Alters the NH3 vs N2H4 Product Profile in Iron‐catalyzed Nitrogen Reduction via Dual Reactivity from an Iron Hydrazido (Fe=NNH2) Intermediate (2023)

Abstract Whereas synthetically catalyzed nitrogen reduction (N 2 R) to produce ammonia is widely studied, catalysis to instead produce hydrazine (N 2 H 4 ) has received less attention despite its considerable mechanistic interest. Herein, we disclose that irradiation of a tris(phosphine)borane (P 3 B ) Fe catalyst, P 3 B Fe + , significantly alters its product profile to increase N 2 H 4 versus NH 3 ; P 3 B Fe + is otherwise known to be highly selective for NH 3 . We posit a key terminal hydrazido intermediate, P 3 B Fe=NNH 2 , as selectivity‐determining. Whereas its singlet ground state undergoes protonation to liberate NH 3 , a low‐lying triplet excited state leads to reactivity at N α and formation of N 2 H 4 . Associated electrochemical and spectroscopic studies establish that N 2 H 4 lies along a unique product pathway; NH 3 is not produced from N 2 H 4 . Our findings are distinct from the canonical mechanism for hydrazine formation, which proceeds via a diazene (HN=NH) intermediate and showcase light as a tool to tailor selectivity.
Formulation of polyurea with improved flame retardant properties (2013)

This article addresses the flame retardancy of polyurea using three different sulfonate salts, sodium diphenylamine-4-sulfonate, 3-(1-pyridinio)-1-propane sulfonate, and ammonium sulfamate, and their combination with some conventional flame retardants. Cone calorimetry and thermogravimetry are used for the evaluation of the flame retardancy and thermal stability. Among the sulfonate salts, ammonium sulfamate shows the best flame retardancy both alone and in combination. The conventional additives that have been used include ammonium polyphosphate, expandable graphite, aluminum diethylphosphinate, melamine polyphosphate, and a chloroalkylphosphonate, as binary and ternary mixtures at 15 wt.% total loading. The nonsulfur-containing binary system exhibits higher ignition time and better flame and smoke resistance than do the ternary mixtures.
pyGeno: A Python package for precision medicine and proteogenomics (2016)

pyGeno is a python package mainly intended for precision medicine applications that revolve around genomics and proteomics. It integrates reference sequences and annotations from Ensembl, genomic polymorphisms from the dbSNP database and data from next-gen sequencing into an easy to use, memory-efficient and fast framework, therefore allowing the user to easily explore subject-specific genomes and proteomes. Compared to a standalone program, pyGeno gives the user access to the complete expressivity of python, a general programming language. Its range of application therefore encompasses both short scripts and large scale genome-wide studies.
Selective and sensitive determination of lactose in low-lactose dairy products with HPAEC-PAD (2017)

The demand for low lactose dairy products is increasing and more different lactose free food is commercially available. The level of lactose in these products decreased during the last years and nowadays a concentration of <0.01% is generally accepted as "lactose free". For the determination of the lactose concentrations in these dairy products a sensitive analysis method is needed. We developed a method for the determination of low concentrations of lactose in a wide range of dairy products. A simple sample preparation with dilution, centrifugation and ultrafiltration is efficient for the isolation of lactose from the sample matrix. In this paper, a new HPAEC-PAD analysis on a CarboPac PA100 column gives a good separation of lactose from the other saccharides. This separation in combination with the PAD detector yields a selective and sensitive method for the quantification at the desired concentrations of lactose in low lactose dairy products.
Ferromagnetic FePt/Au Core/Shell Nanoparticles Prepared by Solvothermal Annealing (2016)

We report a novel multistep process for the preparation of monodisperse ferromagnetic FePt/Au core/shell nanoparticles. Disordered face-centered cubic (fcc) FePt nanoparticles were first synthesized by a polyol method. FePt/Au core/shell superparamagnetic nanoparticles were then produced via a reductive decomposition of gold acetate in the presence of the FePt seed nanoparticles. The FePt/Au core/shell nanoparticles were annealed in benzyl ether using an autoclave reactor at a temperature of 470°C for 3 h at 7 MPa (1000 psi). Morphological, structural, and magnetic characterization of the FePt/Au core/shell nanoparticles was performed before and after the solvothermal annealing. The annealed monodisperse FePt/Au nanoparticles transformed from a disordered superparamagnetic fcc to a partially ordered ferromagnetic L1 <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> phase with a coercivity up to 2.8 kOe at room temperature.
A Mixed-Methods Trial of Broad Band Noise and Nature Sounds for Tinnitus Therapy: Group and Individual Responses Modeled under the Adaptation Level Theory of Tinnitus (2017)

<b>Objectives:</b> A randomized cross-over trial in 18 participants tested the hypothesis that nature sounds, with unpredictable temporal characteristics and high valence would yield greater improvement in tinnitus than constant, emotionally neutral broadband noise. <b>Study Design:</b> The primary outcome measure was the Tinnitus Functional Index (TFI). Secondary measures were: loudness and annoyance ratings, loudness level matches, minimum masking levels, positive and negative emotionality, attention reaction and discrimination time, anxiety, depression and stress. Each sound was administered using MP3 players with earbuds for 8 continuous weeks, with a 3 week wash-out period before crossing over to the other treatment sound. Measurements were undertaken for each arm at sound fitting, 4 and 8 weeks after administration. Qualitative interviews were conducted at each of these appointments. <b>Results:</b> From a baseline TFI score of 41.3, sound therapy resulted in TFI scores at 8 weeks of 35.6; broadband noise resulted in significantly greater reduction (8.2 points) after 8 weeks of sound therapy use than nature sounds (3.2 points). The positive effect of sound on tinnitus was supported by secondary outcome measures of tinnitus, emotion, attention, and psychological state, but not interviews. Tinnitus loudness level match was higher for BBN at 8 weeks; while there was little change in loudness level matches for nature sounds. There was no change in minimum masking levels following sound therapy administration. Self-reported preference for one sound over another did not correlate with changes in tinnitus. <b>Conclusions:</b> Modeled under an adaptation level theory framework of tinnitus perception, the results indicate that the introduction of broadband noise shifts internal adaptation level weighting away from the tinnitus signal, reducing tinnitus magnitude. Nature sounds may modify the affective components of tinnitus via a secondary, residual pathway, but this appears to be less important for sound effectiveness. The different rates of adaptation to broadband noise and nature sound by the auditory system may explain the different tinnitus loudness level matches. In addition to group effects there also appears to be a great deal of individual variation. A sound therapy framework based on adaptation level theory is proposed that accounts for individual variation in preference and response to sound. <b>Clinical Trial Registration:</b> www.anzctr.org.au, identifier #12616000742471.
Evidence for strong mutation bias towards, and selection against, T/U content in SARS-CoV2: implications for attenuated vaccine design (2020)

ABSTRACT Large-scale re-engineering of synonymous sites is a promising strategy to generate attenuated viruses for vaccines. Attenuation typically relies on de-optimisation of codon pairs and maximization of CpG dinculeotide frequencies. So as to formulate evolutionarily-informed attenuation strategies, that aim to force nucleotide usage against the estimated direction favoured by selection, here we examine available whole-genome sequences of SARS-CoV2 to infer patterns of mutation and selection on synonymous sites. Analysis of mutational profiles indicates a strong mutation bias towards T with concomitant selection against T. Accounting for dinucleotide effects reinforces this conclusion, observed TT content being a quarter of that expected under neutrality. A significantly different mutational profile at CDS sites that are not 4-fold degenerate is consistent with contemporaneous selection against T mutations more widely. Although selection against CpG dinucleotides is expected to drive synonymous site G+C content below mutational equilibrium, observed G+C content is slightly above equilibrium, possibly because of selection for higher expression. Consistent with gene-specific selection against CpG dinucleotides, we observe systematic differences of CpG content between SARS-CoV2 genes. We propose an evolutionarily informed gene-bespoke approach to attenuation that, unusually, seeks to increase usage of the already most common synonymous codons. Comparable analysis of H1N1 and Ebola finds that GC3 deviated from neutral equilibrium is not a universal feature, cautioning against generalization of results.
Effect of Temperature on the Life History of the Mealybug <I>Paracoccus marginatus</I> (Hemiptera: Pseudococcidae) (2008)

Effect of temperature on the life history of the mealybug Paracoccus marginatus Williams & Granara de Willink (Hemiptera: Pseudococcidae) was investigated in the laboratory. P. marginatus was able to develop and complete its life cycle at 18, 20, 25, and 30 +/- 1 degrees C. At 15, 34, and 35 degrees C, the eggs hatched after 27.5, 5.9, and 5.5 d of incubation, respectively, but further development of the first-instar nymphs was arrested. No eggs hatched at 37 degrees C. The developmental time for egg to adult was the longest at 18 degrees C for both males and females. Approximately 80-90% of the eggs survived between 20 and 30 degrees C. The highest fecundity was at 25 degrees C with each female producing an average of 300 eggs. Adult longevity, and preoviposition and oviposition periods increased with decreasing temperature up to 25 degrees C. The proportion of females was approximately 42% at 25 degrees C and was between 70 and 80% at 18, 20, and 30 degrees C. Adult males and females required 303.0 and 294.1 degree-days (DD), respectively, to complete their development. The estimated minimum temperature thresholds for the adult males and females were 14.5 and 13.9 degrees C, respectively. For adult males, the estimated optimum and maximum temperature thresholds were 28.7 and 31.9 degrees C; and for adult females, they were 28.4 and 32.1 degrees C, respectively. The ability of P. marginatus to develop, survive, and reproduce successfully between 18 and 30 degrees C suggests that it has the capability to develop and establish in areas within this temperature range.
New modelling approaches to predict wood properties from its cellular structure: image-based representation and meshless methods (2015)

Abstract Key message The real tissue structure, including local anisotropy directions, is defined from anatomical images of wood. Using this digital representation, thermal/mass diffusivity and mechanical properties (stiffness, large deformation, rupture) are successfully predicted for any anatomical pattern using suitable meshless methods. Introduction Wood, an engineering material of biological origin, presents a huge variability among and within species. Understanding structure/property relationships in wood would allow engineers to control and benefit from this variability. Several decades of studies in this domain have emphasised the need to account simultaneously for the phase properties and the phase morphology in order to be able to predict wood properties from its anatomical features. This work is focused on the possibilities offered by meshless computational methods to perform upscaling in wood using actual tissue morphologies obtained by microscopic images. Methods After a section devoted to the representation step, the digital representation of wood anatomy by image processing and grid generation, the papers focuses on three meshless methods applied to predict different macroscopic properties in the transverse plane of wood (spruce earlywood, spruce latewood and poplar): Lattice Boltzmann Method (LBM) allows thermal conductivity and mass diffusivity to be predicted, Material Point Method (MPM) deals with rigidity and compression at large deformations and peridynamic method is used to predict the fracture pathway in the cellular arrangement. Results This work proves that the macroscopic properties can be predicted with quite good accuracy using only the cellular structure and published data regarding the cell wall properties. A whole set of results is presented and commented, including the anisotropic ratios between radial and tangential directions.
Computing consistent normals and colors from photometric data (2003)

We present a method for computing normals and colors from multiple sets of photometric data that are consistent with each other and an underlying lower resolution mesh. Normals are computed by locally adjusting the light source intensities using data from the underlying mesh. Colors are derived from the photometric calculations, and are adjusted by a global color registration, analogous to global geometric registration.
Multiple-α index profiles (1979)

A new class of index profiles is analyzed. These profiles afford new degrees of freedom in profile design, which make it possible to obtain maximum bandwidth over an extended range of wavelengths or at several different wavelengths. A method is developed for calculating pulse dispersion vs wavelength for this generalized class of index profiles.
Semlog: a multiparadigm programming language for knowledge engineering (1988)

SEMLOG is a strongly typed programming language that carefully blends important language features from three programming paradigms: object-oriented, logic, and functional programming. The result is a multiparadigm high-level language that meets the diverse needs of representing domain knowledge. The language provides powerful primitives for effectively representing: domain objects and their attributes, the taxonomic arrangement of domain objects, the interrelationships between domain objects, and rules for making decisions. But more importantly, because the language is strongly typed, these diverse forms of knowledge can be represented without compromising the integrity of the knowledge base.
Impact of reboxetine plus oxybutynin treatment for obstructive sleep apnea on cardiovascular autonomic modulation (2023)

The combination of noradrenergic (reboxetine) plus antimuscarinic (oxybutynin) drugs (reb-oxy) reduced obstructive sleep apnea (OSA) severity but no data are available on its effects on cardiac autonomic modulation. We sought to evaluate the impact of 1-week reb-oxy treatment on cardiovascular autonomic control in OSA patients. OSA patients were randomized to a double-blind, crossover trial comparing 4 mg reboxetine plus 5 mg oxybutynin to a placebo for OSA treatment. Heart rate (HR) variability (HRV), ambulatory blood pressure (BP) monitoring (ABPM) over 24 h baseline and after treatment were performed. Baroreflex sensitivity was tested over beat-to-beat BP recordings. 16 subjects with (median [interquartile range]) age 57 [51-61] years and body mass index 30 [26-36]kg/m<sup>2</sup> completed the study. The median nocturnal HR was 65 [60-69] bpm at baseline and increased to 69 [64-77] bpm on reb-oxy vs 66 [59-70] bpm on placebo (p = 0.02). The mean 24 h HR from ABPM was not different among treatment groups. Reb-oxy administration was not associated with any modification in HRV or BP. Reb-oxy increased the baroreflex sensitivity and did not induce orthostatic hypotension. In conclusion, administration of reb-oxy did not induce clinically relevant sympathetic overactivity over 1-week and, together with a reduction in OSA severity, it improved the baroreflex function.
TORC1 Suppression Predicts Responsiveness to RAF and MEK Inhibition in BRAF- Mutant Melanoma (2013)

RAF and MEK (mitogen-activated or extracellular signal-regulated protein kinase kinase) inhibitors are effective in treating patients with BRAF-mutant melanoma. However, most responses are partial and short-lived, and many patients fail to respond at all. We found that suppression of TORC1 activity in response to RAF or MEK inhibitors, as measured by decreased phosphorylation of ribosomal protein S6 (P-S6), effectively predicted induction of cell death by the inhibitor in BRAF-mutant melanoma cell lines. In resistant melanomas, TORC1 activity was maintained after treatment with RAF or MEK inhibitors, in some cases despite robust suppression of mitogen-activated protein kinase (MAPK) signaling. In in vivo mouse models, suppression of TORC1 after MAPK inhibition was necessary for induction of apoptosis and tumor response. Finally, in paired biopsies obtained from patients with BRAF-mutant melanoma before treatment and after initiation of RAF inhibitor therapy, P-S6 suppression predicted significantly improved progression-free survival. Such a change in P-S6 could be readily monitored in real time by serial fine-needle aspiration biopsies, making quantitation of P-S6 a valuable biomarker to guide treatment in BRAF-mutant melanoma.
Histomorphometric and biochemical effect of various hyaluronans on early osteoarthritis. (1998)

In quantitative evaluation of this short term study using the OA model, native HA-80 and HA-CL presented a superior cartilage protective effect compared to the other native HA.