gebhart/patrepeval huggingface dataset:
Qualität von Mistelextrakten: Ist die Vergleichbarkeit der marktgeführten Präparate möglich? (1999)

Wässrige Extrakte der Europäischen Mistel (Viscum album L.) werden seit den 20er Jahren als Injektionslösungen in der Behandlung von Krebserkrankungen eingesetzt. Die Anwendung der Mistelextrakte ist begründet auf Beobachtungen von Rudolf Steiner. Mit diesen Beobachtungen wurden die ersten Erkenntnisse der anthroposophischen Therapierichtung geschaffen. Die Anwendung der anthroposophischen Mistelpräparate erfolgt auf der Grundlage der Beurteilung des umfassenden und einheitlichen Menschenbildes der einzelnen Patienten. Abweichungen des Menschenbildes, die bei Krebserkrankten auftreten, sind unter der Viscumtherapie zu beheben und die einzelnen Faktoren des Menschenbildes sind wieder mit dem harmonischen Gesamtbild in Einklang zu bringen [1, 2].
[Antithrombotic therapy of atrial fibrillation]. (2000)

Atrial fibrillation is a major source of stroke. During the past decade, large trials demonstrated the efficacy of anticoagulation and, to a lesser extent, aspirin in primary and secondary prevention of stroke in high risk patients with atrial fibrillation. In this article we reviewed the results of these studies and we present the current guidelines for the antithrombotic treatment of atrial fibrillation.
High‐dose hydroxocobalamin achieves biochemical correction and improvement of neuropsychiatric deficits in adults with late onset cobalamin C deficiency (2019)

Cobalamin C (<i>cblC</i>) deficiency is the most common inborn error of intracellular cobalamin metabolism caused by pathogenic variant(s) in <i>MMACHC</i> and manifests with methylmalonic acidemia, hyperhomocysteinemia, and hypomethioninemia with a variable age of presentation. Individuals with late-onset <i>cblC</i> may be asymptomatic until manifesting neuropsychiatric symptoms, thromboembolic events, and renal disease. Although hydroxocobalamin provides a foundation for therapy, optimal dose regimen for adult patients has not been systematically evaluated. We report three adult siblings with late-onset <i>cblC</i> disease, and their biochemical and clinical responses to high-dose hydroxocobalamin. The 28-year-old proband presented with severe psychosis, progressive neurological deterioration, and deep venous thrombosis complicated by a pulmonary embolism. MRI studies identified lesions in the spinal cord, periventricular white matter, and basal ganglia. Serum homocysteine and methylmalonic acid levels were markedly elevated. Hydroxocobalamin at standard dose (1 mg/day) initially resulted in partial metabolic correction. A regimen of high-dose hydroxocobalamin (25 mg/day) together with betaine and folic acid resulted in rapid and sustainable biochemical correction, resolution of psychosis, improvement of neurological functions, and amelioration of brain and spinal cord lesions. Two siblings who did not manifest neuropsychiatric symptoms or thromboembolism achieved a satisfactory metabolic control with the same high-dose regimen. Hydroxocobalamin injection was then spaced out to 25 mg weekly with good and sustainable metabolic control. All three patients are compound heterozygotes for c.271dupA p.Arg91LysfsX14 and c.389A > G p.Tyr130Cys. This study highlights the importance of evaluating intracellular cobalamin metabolism in adults with neuropsychiatric manifestations and/or thromboembolic events, and demonstrates that high-dose hydroxocobalamin achieves rapid and sustainable metabolic control and improvement in neuropsychiatric outcomes in adults with late-onset <i>cblC</i> disease.
Containerization: For Over-the-Air Programming of Field Deployed Internet-of-Energy Based on Cost Effective LPWAN (2020)

Containerization is widely investigated as a secure and lightweight virtualization solution. They have outclassed the traditional virtual machines (VMs) architecture in the cloud because of having built-in capabilities to provide platform-as-a-service (PaaS) to the edge devices. Containers consume less hardware resource, scalable and provide faster patch times, thus they have been suggested as a solution for more practical and real-time virtualization resource in energy utilities. Containers can be used as a replacement for VMs because the main feature of the modern cloud architecture, i.e. workloads are able to utilize shared hardware resources that are provided across all data-center nodes for any purpose. This article reviews the implementation architecture of the containers for energy sector applications, i.e. next-generation substation automation systems. Moreover, we analysed the power consumed by the edge devices, based on the low power wide area network (LPWAN), for over-the-air programming through containers. In addition, we studied the success factors of containers, by considering specific used-cases and explain the benefits of using containers over traditional VMs.
Practical and Highly Stereoselective Technology for Preparation of Enantiopure Sulfoxides and Sulfinamides Utilizing Activated and Functionally Differentiated N‐Sulfonyl‐1,2,3‐oxathiazolidine‐2‐oxide Derivatives. (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
Pulmonary vasodilatory action of endogenous atrial natriuretic factor in rats with hypoxic pulmonary hypertension. Effects of monoclonal atrial natriuretic factor antibody. (1992)

We administered ascitic fluid containing atrial natriuretic factor (ANF) monoclonal antibody to rats after 3 weeks of exposure to hypoxia while the rats were still hypoxic. In additional chronically hypoxic rats, we infused synthetic rat ANF. In conscious chronically instrumented rats, after a bolus dose of 5 micrograms i.v. ANF, pulmonary arterial pressure fell significantly from 26.5 +/- 2 to 21 +/- 2 mm Hg (p less than 0.01), reaching its nadir at 5 minutes without change of systemic arterial pressure, cardiac output, or heart rate. Pulmonary arterial pressure increased gradually from 26 +/- 4 to 34 +/- 4 mm Hg within 30 minutes (p less than 0.05) after acute administration of ANF monoclonal antibody and decreased transiently to return to baseline within 15 minutes after infusion of control ascitic fluid containing monoclonal antibody against an apolipoprotein. Cardiac output and heart rate remained unchanged after both ANF monoclonal antibody and control ascitic fluid. In normoxic rats, acute administration of ANF monoclonal antibody did not cause significant changes in pulmonary arterial pressure, cardiac output, or heart rate. Rats receiving weekly intravenous injections of ANF monoclonal antibody that were started before initiation of exposure to hypoxia experienced significantly aggravated pulmonary hypertension and right ventricular hypertrophy compared with rats receiving repeated infusions of control ascitic fluid. However, there was no significant difference in small pulmonary arterial wall thickness or percentage of muscularized arteries at the alveolar duct level. These results suggest that endogenous ANF attenuates hypoxic pulmonary hypertension by decreasing pulmonary vascular tone.
Detection chain and electronic readout of the QUBIC instrument (2020)

The Q and U Bolometric Interferometer for Cosmology (QUBIC) Technical Demonstrator (TD) aiming to shows the feasibility of the combination of interferometry and bolometric detection. The electronic readout system is based on an array of 128 NbSi Transition Edge Sensors cooled at 350mK readout with 128 SQUIDs at 1K controlled and amplified by an Application Specific Integrated Circuit at 40K. This readout design allows a 128:1 Time Domain Multiplexing. We report the design and the performance of the detection chain in this paper. The technological demonstrator unwent a campaign of test in the lab. Evaluation of the QUBIC bolometers and readout electronics includes the measurement of I-V curves, time constant and the Noise Equivalent Power. Currently the mean Noise Equivalent Power is ~ 2 x 10<sup>-16</sup>W= p &radic;Hz
Prospective urodynamic evaluation of the efficacy of prostatic balloon dilatation (1992)

Abstract In order to evaluate the ability of transurethral prostatie balloon dilatation (TUPBD) to effectively treat prostatic obstruction, 18 men (aged 53–77 years) with obstructive small prostate glands were evaluated with symptom scores and urodynamic studies before and 6 and 12 months after TUPBD utilizing the endoscopically placed Advanced Surgical Intervention 75F balloon. After TUPBD, 81% of men reported some improvement in their symptoms with statistical significance (P &lt;.05) at 6 and 12 months after the procedure. The mean non‐invasive peak flow rate did not change significantly after TUPBD. Although the mean maximum voiding pressure (Pv max) and the maximum detrusor pressure at peak flow (Pq max) were reduced at 6 and 12 months postoperatively, the changes were found to be statistically insignificant (P &gt;.05). In addition, the use of Abrams and Griffiths pressure‐flow nomogram revealed a “non‐obstructive” pressure‐flow study in only one patient at 6 and 12 after TUPBD. Although TUPBD results in some symptomatic improvement, on pressure‐flow analysis the majority of men remain obstructed at 6 and 12 months after the procedure.
Self-Mixing Laser Sensor for Large Displacements: Signal Recovery in the Presence of Speckle (2012)

Laser self-mixing (SM) sensors are successfully used to measure displacement in the absence of speckle. However, speckle deforms the SM signal rendering it unusable for standard displacement extraction techniques. This article proposes a new signal-processing technique, based on tracking the signal envelope, to remedy this problem. Algorithm was successfully employed to measure long-range displacements (25 mm), in the presence of speckle and the lateral movement of the target, both causing severe corruption of the SM signal. It therefore enabled the use of the sensor on noncooperative targets without the need for sensor positioning and/or alignment. The results have been obtained for SM signals in which the envelope amplitude is varied by a factor of 28, without the loss of interferometric fringes. The use of this technique effectively removes the need for opto/electro-mechanical components traditionally used to measure long-range displacement in the presence of speckle.
Using Technology as a Tool to Enhance Teaching and Learning (1999)

Successful school program innovation must incorporate technology as a tool to enhance teaching and learning. West Junior High School integrates technology into the curriculum to complement and enhance its mission to help all learners explore and attain results that only a technology-rich, student-centered learning environment can offer.
Soft, skin-interfaced microfluidic systems with integrated immunoassays, fluorometric sensors, and impedance measurement capabilities (2020)

Soft microfluidic systems that capture, store, and perform biomarker analysis of microliter volumes of sweat, in situ, as it emerges from the surface of the skin, represent an emerging class of wearable technology with powerful capabilities that complement those of traditional biophysical sensing devices. Recent work establishes applications in the real-time characterization of sweat dynamics and sweat chemistry in the context of sports performance and healthcare diagnostics. This paper presents a collection of advances in biochemical sensors and microfluidic designs that support multimodal operation in the monitoring of physiological signatures directly correlated to physical and mental stresses. These wireless, battery-free, skin-interfaced devices combine lateral flow immunoassays for cortisol, fluorometric assays for glucose and ascorbic acid (vitamin C), and digital tracking of skin galvanic responses. Systematic benchtop evaluations and field studies on human subjects highlight the key features of this platform for the continuous, noninvasive monitoring of biochemical and biophysical correlates of the stress state.
An Improved Method for Critical Focus of Motion-Picture Optical Printers (1971)

The LogEtronics, Inc., Focatron Image Sharpness Meter, when used as a tool to determine optimum focus on motion-picture optical printers, yields accurate results in a simple and efficient manner. The Focatron unit was tested and found successful in an Eastman Kodak Co. motion-picture laboratory where high quality requirements exist. This unit proved particularly useful during daily printer changeovers and provided the operators with a convenient and simple method to afford daily printer focus checks.
Recent advances in alkoxy radical-promoted C–C and C–H bond functionalization starting from free alcohols (2019)

Direct functionalization of inert C(sp3)-C(sp3) and C(sp3)-H bonds represents one of the most valuable synthetic tactics, yet large obstacles remain in terms of reactivity and selectivity. Alkoxy radicals enable C-C bond scission via β-C elimination and C(sp3)-H bond cleavage through a hydrogen atom transfer (HAT) process, thus providing an efficient method to address these problems. In view of atom- and step-economy, the direct use of abundant alcohols as alkoxy radical precursors in radical transformations is of high synthetic value. This feature article summarizes our recent achievements in (a) C(sp3)-C(sp3) bond cleavage via ring-opening of cycloalkanols and (b) site-specific C(sp3)-H functionalization of unprotected aliphatic alcohols, along with the reconstruction of various new chemical bonds, e.g. C-halogen, C-C, C-N, C-S, and C-Se bonds.
Purification and primary structure of novel lipid transfer proteins from germinated lentil (Lens culinaris) seeds (2007)

A subfamily of eight novel lipid transfer proteins designated as Lc-LTP1-8 was found in the lentil Lens culinaris. Lc-LTP2, Lc-LTP4, Lc-LTP7, and Lc-LTP8 were purified from germinated lentil seeds, and their molecular masses (9268.7, 9282.7, 9121.5, 9135.5 daltons) and complete amino acid sequences were determined. The purified proteins consist of 92-93 amino acid residues, have four disulfide bonds, and inhibit growth of Agrobacterium tumefaciens. Total RNA was isolated from germinated lentil seeds, RT-PCR and cloning were performed, and the cDNAs of six LTPs were sequenced. Precursor 116-118-residue proteins with 24-25-residue signal peptides were found, and two of them are purified proteins Lc-LTP2 and Lc-LTP4.
Proposal and Initial Study for Animal Crowdsourcing (2014)

We focus on animals as a resource of processing capability in crowdsourcing and propose an Animal Crowdsourcing (we call it "Animal Cloud”, too) that resolves problems with cooperation between computers and human or animals. This paper gives an overview of Animal Crowdsourcing and reports on the interim results of our learning experiments using rats (Long-Evans rats) to verify the feasibility of Animal Crowdsourcing.
Measurement of interspin distances by EPR (2008)

The determination of electron–electron interspin distances by continuous wave (CW) and pulsed EPR is reviewed for the period from late 2003 to early 2008. Papers that provide new methodology are highlighted. The wide range of applications is summarized in tables.
Characterization of t-loop formation by TRF2 (2020)

T-loops are thought to hide telomeres from DNA damage signaling and DSB repair pathways. T-loop formation requires the shelterin component TRF2, which represses ATM signaling and NHEJ. Here we establish that TRF2 alone, in the absence of other shelterin proteins can form t-loops. Mouse and human cells contain two isoforms of TRF2, one of which is uncharacterized. We show that both isoforms protect telomeres and form t-loops. The isoforms are not cell cycle regulated and t-loops are present in G1, S, and G2. Using the DNA wrapping deficient TRF2 Topless mutant, we confirm its inability to form t-loops and repress ATM. However, since the mutant is also defective in repression of NHEJ and telomeric localization, the role of topological changes in telomere protection remains unclear. Finally, we show that Rad51 does not affect t-loop frequencies or telomere protection. Therefore, alternative models for how TRF2 forms t-loops should be explored.
Deep Freezing of Boar Semen II. Effects of Method of Dilution, Glycerol Concentration, and Time of Semen-Glycerol Contact on Survival of Spermatozoa (1973)

Five factorial experiments were conducted to examine the effects of glycerol concentration and processing procedures prior to freezing on the revival of boar spermatozoa upon thawing.
Hexameric Aggregates in Crystalline (Pentamethylcyclopentadienyl)gallium(I) at 200 K (1997)

A hexameric cluster with only weak metal–metal bonding is found in crystalline (pentamethylcyclopentadienyl)gallium(I). A shell of η5-C5Me5 ligands encloses a near-octahedral Ga6 array with unusually long Ga…︁Ga distances (407.3 and 417.2 pm, see picture on the right).
Benchmarking and management of fugitive dust emissions from surface-mine haul roads (2002)

Dust generation from haul roads is a problem for most surface coal-mining operations and especially those in semi-arid and arid areas. For these mines, which rarely have optimally designed and maintained roads, classifying different levels of dustiness, quantifying the impact on safety and assigning priorities within the constraints of limited capital and manpower are problematic. Techniques have now been developed for the description of fugitive dust emissions associated with ultra-heavy mine haul trucks running on unpaved mine haul roads. Benchmarks are established as five degrees of 'dust defect' for trucks travelling at 40 km/h, and computer models are used to assess the likely dustiness of haul roads as a function of surface loading of fines, traffic types and volume, together with various material parameters. For a typical South African Highveld colliery haul road reapplication intervals for water spraying were found to vary from 33 to 63 minutes for rear-dump trucks and from 21 to 41 minutes for bottom-dump trucks between summer and winter operation. The models can be applied, in conjunction with the results of quantitative exposure profiling, in management and mitigation strategies for water-based spraying.
Nonlinear optical response of silica and hyybrid silica/silicon disc micro resonators (2009)

In this paper a bistable operation of silica micro disc resonators and hybrid ones made of silica/silicon has been investigated experimentally. It has been found, that in a hybrid silica/silicon micro resonators a bistability effect has an opposite sign in comparison with a silica disc micro resonator. The bistable behavior of silica micro resonators caused by a thermal nonlinearity exhibits transmission spectrum shift into a longer wavelength region.
GHz-drive Magnetic Thin-film Inductor Using CoNbZr Film. (2000)

Thin-film inductors with micro-patterned CoNbZr films for impedance-matching elements in a 1-GHz-drive mobile communication handsets application have been demonstrated for the first time. Narrow slit trains along the easy axis direction and a square spiral coil control the ferromagnetic resonance frequency through changes in shape anisotropy energy and magnetostatic energy. Inductance increased by 18% compared with the air core inductor, while Q was almost the same.
On Using the Shot Noise in SIS Tunnel Junctions for Characterizing IF Amplifiers (1995)

The IF amplifier in SIS heterodyne mixers can represent a major contribution to the receiver noise. Achieving quantum limited performance of SIS receivers will require accurate measurement and characterization of this noise contribution. A standard method for in situ characterization of the IF amplifier uses the shot noise from the SIS tunnel junction biased above the gap voltage as a calibrated noise source. This provides an accurate measurement of the IF amplifier noise and gain for source impedances equal to the normal state resistance of the junction, Rn . This paper describes an extension of this technique to determine the 2-port noise and gain parameters of the IF amplifier by using the junction as a noise source over its full dc bias range. Measuring the IF output power over the full bias range (with no LO applied) samples the IF amplifier response for source impedances ranging from zero to > 10R. The IF amplifier characteristics are obtained by fitting the measurements to a six parameter model of the IF amplifier system. Although there is insufficient data to accurately determine the standard noise and gain parameters, the contribution from the IF system to the receiver noise is accurately determined. This method of characterizing the IF system references the noise and gain parameters to the plane of the tunnel junction and includes the effect of the circuitry between the junction and the IF amplifier. This is particularly useful for receivers which don't use standard 50 ohm amplifiers with cooled isolators. This paper describes the IF noise and gain model together with the fitting procedure. Examples of this technique applied to the receivers used on the Owens Valley Radio Observatory millimeter array are presented. These receivers include mixers with integrated IF transformers and mixers with integrated HEMT amplifiers.
International symposium on Flying Insects and Robots, Book of Abstracts (2007)

Keywords: Flying Robots ; Flying Insects ; Mechatronics ; Miniaturization ; Aerodynamics ; Aerial Robotics Note: The book contains all invited and peer-reviewed contributions presented at the conference Reference LIS-BOOK-2007-001 URL: http://fir.epfl.ch/ Record created on 2007-09-17, modified on 2017-05-10
Augmentation of Image Compression System and Security Exploiting Random Permutation (2016)

In valuable circumstance encryption should be performed before the image compression. In case encryption is not performed then there might be the potential outcomes of taking the information. Thusly we have proposed structure where encryption is done going before the image compression. Here we have considered both the sorts of weight - Lossless and Lossy weight. Weight is done in the estimate territory where experts make sense of the desire screw up of each pixel then encryption is associated on them by sporadic stage. Gauge range gives the strange condition of security. A vast part of the current ETC courses of action incite basic discipline on the weight efficiency. In this paper we are proposing another strategy named as Improvising Image weight System by Random Permutation. where weight is associated on the bundles of encoded image. So image got at the recipient end has each one of the properties of one of a kind image. Here, the estimation missteps are changed by perfect worth trade standard. Furthermore, the host image is divided into different pixel subsets and the colleague information of a subset is continually embedded into the estimation botches in the accompanying subset. A Recipient can adequately remove the embedded puzzle data and recover the primary substance in the subsets with an inverse solicitation. Thusly, an extraordinary reversible data disguising execution is expert.