gebhart/patrepeval huggingface dataset:
Sex-Specific Associations of Maternal Gestational Glycemia with Hormones in Umbilical Cord Blood at Delivery (2016)

<b>Background</b> Few studies have examined sex-specific associations of maternal gestational glycemia with cord blood hormones, which might predict later health. <b>Methods</b> In 976 women without pre-existing diabetes in the Project Viva cohort, we used linear regression to examine associations of maternal gestational glycemia with cord hormone concentrations, adjusted for maternal characteristics and stratified by infant sex. <b>Results</b> A total of 6.1% of women had gestational diabetes mellitus (GDM), 8.8% isolated hyperglycemia, 3.2% gestational impaired glucose tolerance, and 81.9% were normoglycemic. In boys, compared with infants of normoglycemic mothers, infants of GDM mothers had higher cord levels of IGF-2 (β 35.55 ng/mL; 95% CI: 2.60, 68.50), IGFBP-3 (111.2 ng/mL; 5.53, 216.8), insulin (4.66 uU/mL; 2.38, 6.95), C-peptide (0.46 ng/mL; 0.25, 0.67), and leptin (3.51 ng/mL; 1.37, 5.64), but lower IGF-1 (-6.71 ng/mL; -12.7, - 0.76, adjusted for IGFBP-3). In girls, GDM offspring had higher cord blood levels of IGF-1 adjusted for IGFBP-3 (12.45 ng/mL; 4.85, 20.04). Boys, but not girls, of mothers with abnormal glucose tolerance but not GDM also had higher levels of some hormones. <b>Conclusion</b> GDM was associated with growth factors and adipokines in cord blood from boys, but only IGF-1 in girls. These findings suggest sex differences in responses to fetal overnutrition.
Dielectric Properties at Microwave Frequencies of Epoxy Undergoing Cure (1991)

It is well known that the kinetics and the reaction mechanism of epoxy curing determine the final network morphology and ultimately the physical properties of the epoxy resin. In recent years, the introduction of microwave processing of thermosetting materials has prompted the need for comprehensive microwave dielectric data, necessary to properly interpret the cure mechanism induced by electromagnetic radiation. In situ measurements at 2.45 GHz of the complex dielectric constant of an epoxy formulation undergoing thermal cure have been compared with theoretical predictions, based on changes in the dipole concentration and the changes in the relaxation time of the epoxy matrix with extent of cure. It has been shown that the rate of decrease of the dielectric constant primarily reflects the rate of crosslinking within the resin.
La sentence arbitrale du 25 février 1967 rendue par Edward Hambro dans l'affaire de l'immunité d'impôt des employés de l'Euratom travaillant au Royaume-Uni dans le cadre du Projet Dragon (1970)

Salmon Jean. La sentence arbitrale du 25 février 1967 rendue par Edward Hambro dans l'affaire de l'immunité d'impôt des employés de l'Euratom travaillant au Royaume-Uni dans le cadre du Projet Dragon. In: Annuaire français de droit international, volume 16, 1970. pp. 446-452.
Smoothing clickthrough data for web search ranking (2009)

Incorporating features extracted from clickthrough data (called clickthrough features) has been demonstrated to significantly improve the performance of ranking models for Web search applications. Such benefits, however, are severely limited by the data sparseness problem, i.e., many queries and documents have no or very few clicks. The ranker thus cannot rely strongly on clickthrough features for document ranking. This paper presents two smoothing methods to expand clickthrough data: query clustering via Random Walk on click graphs and a discounting method inspired by the Good-Turing estimator. Both methods are evaluated on real-world data in three Web search domains. Experimental results show that the ranking models trained on smoothed clickthrough features consistently outperform those trained on unsmoothed features. This study demonstrates both the importance and the benefits of dealing with the sparseness problem in clickthrough data.
Robust Resampling Detection in Digital Images (2012)

To create convincing forged images, manipulated images or parts of them are usually exposed to some geometric operations which require a resampling step. Therefore, detecting traces of resampling became an important approach in the field of image forensics. In this paper, we revisit existing techniques for resampling detection and design some targeted attacks in order to assess their reliability. We show that the combination of multiple resampling and hybrid median filtering works well for hiding traces of resampling. Moreover, we propose an improved technique for detecting resampling using image forensic tools. Experimental evaluations show that the proposed technique is good for resampling detection and more robust against some targeted attacks.
ChemInform Abstract: The Synthesis of Angularly Fused Tricyclic Compounds via Tandem Ring Closing Metathesis Reactions. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Optimized holographic optical traps (2005)

Holographic optical traps use the forces exerted by computer-generated holograms to trap, move and otherwise transform mesoscopically textured materials. This article introduces methods for optimizing holographic optical traps' efficiency and accuracy, and an optimal statistical approach for characterizing their performance. This combination makes possible real-time adaptive optimization.
Azbel Phenomenology and Simple Simulations (1999)

Even an author who complains about the age of her coauthors is likely to reach their age; and finally we will all die. Death is unavoidable also for animals and plants as well as bacteria (provided we define the splitting of a bacterial cell into two cells as the death of the parent cell). And most Olympic records are held by athletes younger than the present authors. Thus physical fitness (as opposed to scientific wisdom) decreases with age during human adulthood, while the probability q to die within the next year increases. For computer simulations, the latter effect, the increase of mortality q with age a, is particularly suitable to define ageing, compared e.g. to studies of beauty.
Adaptive One-Bit Compressive Sensing with Application to Low-Precision Receivers at mmWave (2015)

Multiple input multiple output (MIMO) systems employing large antenna arrays are the basic architecture for millimeter wave (mmWave) systems. Due to the higher bandwidths to be used at mmWave, the corresponding sampling rates of high-resolution analog-to-digital converters (ADCs) are also very high, so that ADCs become the most power hungry devices in the reception chain. One solution is to employ low resolution, i.e. one-bit, ADCs. We develop an adaptive one-bit compressed sensing scheme that can be used at low-resolution mmWave receivers for channel estimation. The simulation results show that the adaptive one-bit compressed sensing scheme outperforms the fixed one in the context of mmWave channel estimation.
Multipolar complexes–II The self association of ‐NO2 ‐CN and ‐COCN polar groups (1969)

Abstract Fluorine nuclear magnetic resonance (F‐NMR) has been used to determine dissociation constants for multipolar complexes formed by several p ‐substituted fluorobenzenes in CCl 4 and cyclohexane at 25°. Data in CCl 4 were also obtained at −20°. The results are interpreted in simplified terms as dipole‐dipole interactions which lead to a complex of net zero dipole moment. Although the dissociation constants are not of high accuracy, the values obtained do indicate that both polarity and steric effects are important in the presumed multipolar complexes.
Blockchain Economies: The Crowd as the Market Maker (2016)

This chapter contains sections titled: Understanding Decentralized Peer-to-Peer Exchange, Value Creation and Capture in Decentralized Exchange, Some Challenges and Opportunities
Effects of OP-1206 (Prostaglandin E1) on Nerve-Conduction Velocity in the Dog Cauda Equina Subjected to Acute Experimental Compression (1996)

The effect of OP-1206, a prostaglandin E1 derivative, on cauda equina function was analyzed in a model for acute cauda equina compression in the dog. An inflatable balloon was placed under the lamina of the seventh lumbar vertebra in the dog and muscle action potential area (MAP area) and nerve-conduction velocity (NCV) were monitored during 2 h of compression and 1.5 h of recovery. OP-1206 was infused systemically at three concentrations. Only the highest concentration (30 ng/kg/min) of OP-1206 could prevent the reduction in NCV. However, this concentration had no similar effect on the MAP area. The data suggest the potential therapeutic use of prostaglandin E1 analogues for the future treatment of intermittent claudication.
L'Irrésistible Désir de naissance (1986)

Cette édition numérique a été réalisée à partir d’un support physique, parfois ancien, conservé au sein du dépôt légal de la Bibliothèque nationale de France, conformément à la loi n° 2012-287 du 1er mars 2012 relative à l’exploitation des Livres indisponibles du XXe siècle.
Elongational Flow of Solutions of Rodlike Micelles (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElongational Flow of Solutions of Rodlike MicellesRobert K. Prud'homme and Gregory G. WarrCite this: Langmuir 1994, 10, 10, 3419–3426Publication Date (Print):October 1, 1994Publication History Published online1 May 2002Published inissue 1 October 1994https://pubs.acs.org/doi/10.1021/la00022a010https://doi.org/10.1021/la00022a010research-articleACS PublicationsRequest reuse permissionsArticle Views402Altmetric-Citations78LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Aminopeptidase activities of Propionibacterium freudenreichii dairy isolates (2002)

Abstract – This study was undertaken to achieve more information on the aminopeptidase activities expressed in Propionibacterium freudenreichii strains naturally occurring in milk and dairy products. Fifty four strains belonging to both subspecies freudenreichii and shermanii were analyzed for activity towards different amino acyl β-naphthylamide (βNA) derivatives. The ability to efficiently hydrolyze aminoterminal leucine was common to all the isolates, with notably high activities for five strains. Proline iminopeptidase activity was generally expressed. Accordingly, PCR targeted to the P. freudenreichii ATCC 9617 prolyl iminopeptidase encoding gene (pip) demonstrated its presence in all but three strains. Activity towards Lys- and Arg-βNA was less expressed and strain-dependent. The X-prolyl-dipeptidyl aminopeptidase activity was relatively low in absence of NaCl. It increased in presence of 3 % NaCl only toward Phe-Pro-βNa and not toward Gly-Pro-βNA. The substrate Glu-βNA was not cleaved by any strain. Findings suggest that the adventitious P. freudenreichii strains may have a significant and variable effect on secondary proteolysis of hard cheeses, being a possible factor of organoleptic differences. Key words: Propionibacterium freudenreichii, aminopepdidases activity, adventitious strains.
Abnormal Resting-State Functional Connectivity in Patients with Chronic Fatigue Syndrome: Results of Seed and Data-Driven Analyses (2015)

Although altered resting-state functional connectivity (FC) is a characteristic of many chronic pain conditions, it has not yet been evaluated in patients with chronic fatigue. Our objective was to investigate the association between fatigue and altered resting-state FC in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Thirty-six female subjects, 19 ME/CFS and 17 healthy controls, completed a fatigue inventory before undergoing functional magnetic resonance imaging. Two methods, (1) data driven and (2) model based, were used to estimate and compare the intraregional FC between both groups during the resting state (RS). The first approach using independent component analysis was applied to investigate five RS networks: the default mode network, salience network (SN), left frontoparietal networks (LFPN) and right frontoparietal networks, and the sensory motor network (SMN). The second approach used a priori selected seed regions demonstrating abnormal regional cerebral blood flow (rCBF) in ME/CFS patients at rest. In ME/CFS patients, Method-1 identified decreased intrinsic connectivity among regions within the LFPN. Furthermore, the FC of the left anterior midcingulate with the SMN and the connectivity of the left posterior cingulate cortex with the SN were significantly decreased. For Method-2, five distinct clusters within the right parahippocampus and occipital lobes, demonstrating significant rCBF reductions in ME/CFS patients, were used as seeds. The parahippocampal seed and three occipital lobe seeds showed altered FC with other brain regions. The degree of abnormal connectivity correlated with the level of self-reported fatigue. Our results confirm altered RS FC in patients with ME/CFS, which was significantly correlated with the severity of their chronic fatigue.
Targeting the Multidrug Transporter Ptch1 Potentiates Chemotherapy Efficiency (2018)

One of the crucial challenges in the clinical management of cancer is resistance to chemotherapeutics. Multidrug resistance (MDR) has been intensively studied, and one of the most prominent mechanisms underlying MDR is overexpression of adenosine triphosphate (ATP)-binding cassette (ABC) transporters. Despite research efforts to develop compounds that inhibit the efflux activity of ABC transporters and thereby increase classical chemotherapy efficacy, to date, the Food and Drug Administration (FDA) has not approved the use of any ABC transporter inhibitors due to toxicity issues. Hedgehog signaling is aberrantly activated in many cancers, and has been shown to be involved in chemotherapy resistance. Recent studies showed that the Hedgehog receptor Ptch1, which is over-expressed in many recurrent and metastatic cancers, is a multidrug transporter and it contributes to the efflux of chemotherapeutic agents such as doxorubicin, and to chemotherapy resistance. Remarkably, Ptch1 uses the proton motive force to efflux drugs, in contrast to ABC transporters, which use ATP hydrolysis. Indeed, the "reversed pH gradient" that characterizes cancer cells, allows Ptch1 to function as an efflux pump specifically in cancer cells. This makes Ptch1 a particularly attractive therapeutic target for cancers expressing Ptch1, such as lung, breast, prostate, ovary, colon, brain, adrenocortical carcinoma, and melanoma. Screening of chemical libraries have identified several molecules that are able to enhance the cytotoxic effect of different chemotherapeutic agents by inhibiting Ptch1 drug efflux activity in different cancer cell lines that endogenously over-express Ptch1. In vivo proof of concept has been performed in mice where combining one of these compounds with doxorubicin prevented the development of xenografted adrenocortical carcinoma tumors more efficiently than doxorubicin alone, and without obvious undesirable side effects. Therefore, the use of a Ptch1 drug efflux inhibitor in combination with classical or targeted therapy could be a promising therapeutic option for Ptch1-expressing cancers.
Distributed Learning for Vehicle Routing Decision in Software Defined Internet of Vehicles (2020)

With the increasing number of vehicles, the traffic congestion is becoming more and more serious. In order to alleviate such a problem, this article considers transmission and inference delay of cloud centralized computing in the software defined Internet of Vehicles (SDIoV), and builds a new SDIoV architecture based on edge intelligence, for supporting real-time vehicle routing decision through distributed multi-agent reinforcement learning model. Then, a software defined device collaboration optimization method is designed to improve the efficiency of distributed training. Combined with multi-agent reinforcement learning, a distributed-learning-based vehicle routing decision algorithm (DLRD) is proposed to adaptively adjust vehicle routing online. The performed simulations show that the DLRD can successfully realize real-time routing decision for vehicles and alleviate traffic congestion with the dynamic changes of the road environment.
ChemInform Abstract: CHROMCHALKOGENIDE 5. MITT. MISCHKRISTALLBLDG. IN DEN SYST. CO(1‐X)NI(X)CR2S4 UND CO(1‐X)CU(X)CR2S4 (1973)

Abstract Durch Zusammensintern der Elemente bzw. der binären Sulfide wurde die gegenseitige Mischbarkeit in den Systemen CoCrz S4‐NiCr2 S4, CuCr 2 S 4 ‐NiCr2S4 und CoCr 2 S 4 ‐CuCr2S4 untersucht.
Noninvasive Assessment of Hepatic Triglyceride Content in Humans With 13C Nuclear Magnetic Resonance Spectroscopy (1996)

Hepatic lipid content was assessed noninvasively in 15 patients with hepatic steatosis by 13C nuclear magnetic resonance (NMR) spectroscopy, and compared in a double-blind fashion with histological grading and morphometric quantitation of fat in liver biopsies taken within 2 weeks of the study. The lipid content in the liver biopsies was expressed as the volume fraction of total parenchyma occupied by fat. Hepatic triglyceride content was determined by comparing the 13C NMR signal intensity in vivo with the signal intensity obtained from a lipid phantom of known concentrations. There was an approximately 30-fold increase in the 13C NMR signals of the saturated carbons (methyl/methylene [CH2]n) region of hepatic triglycerides from patients with grade 4 steatosis compared with those with grade 0, yielding a good dynamic range for measuring hepatic triglyceride content. The correlation coefficient between the morphometric and 13C NMR techniques was 0.89 (P < .01). These studies demonstrate that 13C NMR spectroscopy can be used to noninvasively assess hepatic triglyceride content in humans. This method may be clinically useful for diagnosis and follow-up of patients with hepatic steatosis.
Journal of Medicinal Chemistry (1968)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTJournal of Medicinal ChemistryCite this: Anal. Chem. 1968, 40, 2, 169APublication Date (Print):February 1, 1968Publication History Published online22 May 2012Published inissue 1 February 1968https://doi.org/10.1021/ac60258a860RIGHTS & PERMISSIONSArticle Views55Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (476 KB) Get e-Alerts Get e-Alerts
Adaptive Modeling of Non-rigid Assembly Orientation Processes in a Statistical CAT Simulation (2015)

One of the most common uses for Computer Aided Tolerancing (CAT) in the passenger car industry is body design, which universalized, consists of non-rigid assembly processes. There are a number of theoretical approaches to model the joining behavior of assemblies with elastic FEM approaches combined with statistical computation. On the other hand the rising complexity of today's body-in-white production chain makes simplifications inevitable when fast results for tolerance optimization are required. Multiple use-cases representing different scenarios are analyzed. The scenarios vary in the stiffness of the involved components, the joining environment and the general geometrical set-up. Comparing mass production measurement data with simulation output reveals the limits of CAT simulations in certain cases. One of those cases is where so-called geo-stations improve the dimensional output quality of assemblies compared to the single parts. To account for this phenomenon an adaptive approach to model geo-stations in different ways is presented, i.e. as an entity either provoking an additional influence of deviation or supplying geometrical correction. A matrix is used to suggest the appropriate kind of modeling depending on the deduced parameters.
FORUM Mechanisms of Hepatotoxicity (2001)

This review addresses recent advances in specific mechanisms of hepatotoxicity. Because of its unique metabolism and relationship to the gastrointestinal tract, the liver is an important target of the toxicity of drugs, xenobiotics, and oxidative stress. In cholestatic disease, endogenously generated bile acids produce hepatocellular apoptosis by stimulating Fas translocation from the cytoplasm to the plasma membrane where self-aggregation occurs to trigger apoptosis. Kupffer cell activation and neutrophil infiltration extend toxic injury. Kupffer cells release reactive oxygen species (ROS), cytokines, and chemokines, which induce neutrophil extravasation and activation. The liver expresses many cytochrome P450 isoforms, including eth-anol-induced CYP2E1. CYP2E1 generates ROS, activates many tox-icologically important substrates, and may be the central pathway by which ethanol causes oxidative stress. In acetaminophen toxicity, nitric oxide (NO) scavenges superoxide to produce peroxynitrite,
Dye-Sensitized Nonstoichiometric Strontium Titanate Core–Shell Photocathodes for Photoelectrosynthesis Applications (2021)

A core-shell approach that utilizes a high-surface-area conducting core and an outer semiconductor shell is exploited here to prepare p-type dye-sensitized solar energy cells that operate with a minimal applied bias. Photocathodes were prepared by coating thin films of nanocrystalline indium tin oxide with a 0.8 nm Al<sub>2</sub>O<sub>3</sub> seeding layer, followed by the chemical growth of nonstoichiometric strontium titanate. Films were annealed and sensitized with either a porphyrin chromophore or a chromophore-catalyst molecular assembly consisting of the porphyrin covalently tethered to the ruthenium complex. The sensitized photoelectrodes produced cathodic photocurrents of up to -315 μA/cm<sup>2</sup> under simulated sunlight (AM1.5G, 100 mW/cm<sup>2</sup>) in aqueous media, pH 5. The photocurrent was increased by the addition of regenerative hole donors to the system, consistent with slow interfacial recombination kinetics, an important property of p-type dye-sensitized electrodes.