gebhart/patrepeval huggingface dataset:
Facilities for Automotive Gas Turbine Ceramic Components (1997)

The first part of this paper describes the test facility to characterize the catalytic combustor. The combustion chamber is a LPP combustor (Lean Premixed Prevaporised), made of preheater, premix duct, catalytic part and after burner. Each component will be validated separately for the required conditions (steady state and transient conditions). All the measurements and data acquisition are described. The second part deals with the test facility for the hot spin test of the ceramic wheel. The base of the test bench is a modified turbocharger (maximum rotating speed: 125000 r.p.m.). With this configuration it will be possible to test the ceramic radial wheel within the AGATA specifications; in this case the compressor is used like a brake. The last part is devoted to two ceramic heat exchanger test rigs: the first rig is to evaluate the themomechanical stresses on the samples; the second rig to assess the performance compared to the AGATA specifications and to duplicate the transient and thermal shock conditions. In this program the heat exchanger is fixed.
Portable, unobtrusive garbage collection for multiprocessor systems (1994)

We describe and prove the correctness of a new concurrent mark-and-sweep garbage collection algorithm. This algorithm derives from the classical on-the-fly algorithm from Dijkstra et al. [9]. A distinguishing feature of our algorithm is that it supports multiprocessor environments where the registers of running processes are not readily accessible, without imposing any overhead on the elementary operations of loading a register or reading or initializing a field. Furthermore our collector never blocks running mutator processes except possibly on requests for free memory; in particular, updating a field or creating or marking or sweeping a heap object does not involve system-dependent synchronization primitives such as locks. We also provide support for process creation and deletion, and for managing an extensible heap of variable-sized objects.
A Generalization of Sampling Without Replacement from a Finite Universe (1952)

Abstract This paper presents a general technique for the treatment of samples drawn without replacement from finite universes when unequal selection probabilities are used. Two sampling schemes are discussed in connection with the problem of determining optimum selection probabilities according to the information available in a supplementary variable. Admittedly, these two schemes have limited application. They should prove useful, however, for the first stage of sampling with multi-stage designs, since both permit unbiased estimation of the sampling variance without resorting to additional assumptions.
Eye Movements and Reading Speed in Macular Disease: Influence of Fixation Clusters (2015)

International audience
Half-Bridge Boost Rectifier as Powr Factor Corrector-Electronic Baht (2000)

A low cost and high power factor electronic ballast is presented in this paper. The proposed topology is based on a single power stage, which integrates the power factor corrector (PFC) and the lamp driver stages. The ballast is obtained by integrating the half bridge Boost converter, operating as both rectifier and PFC stage, and the half bridge LC resonant inverter as lamp ballast. The lamp power regulation against line voltage variations is achieved by frequency control. Theoretical analysis and experimental results have been obtained for 26 watts compact fluorescent lamp operating at variable frequency when the input voltage changes from +lo% and -15%.
Repetitive Microstimulation Alters the Cortical Representation of Movements in Adult Rats (1990)

In order to examine the effects of repetitive stimulation on functional cortical organization, standard intracortical microstimulation (ICMS) techniques were used to generate maps of movement representations in motor cortex of rat. After identification of caudal and rostral forelimb fields and adjacent vibrissae and neck fields, one or more representational borders were defined in greater detail. Then a microelectrode was introduced into one of these representational fields, and ICMS current pulses were delivered at a rate of 1/sec for 1 to 3 hr. Following repetitive ICMS, significant changes in movement representations were observed using current levels that were either suprathreshold or subthreshold for evoking the site-specific movement. Electromyographic activity could be evoked at suprathreshold and near-threshold current levels, but not at the subthreshold current levels used here. Significant border shifts ranged from 210 to 670 microns. In each case in which shifts occurred, there appeared to be expansion of the movement represented at the repetitively stimulated site. The effects were progressive and reversible. These results suggest that at least under these unusual experimental circumstances, large representational changes can be generated very rapidly within motor cortex in the absence of any evident peripheral feedback.
Clinical Recruitment Stumbles on a Logo (2003)

A push by the Department of Health and Human Services (HHS) to approve all publications centrally has got clinical researchers hopping mad at one HHS agency, the National Institutes of Health (NIH). Since last fall, according to government scientists, NIH has canceled patient recruitment ads, costing an extra $81,000 and triggering a significant drop in calls from people interested in volunteering.
γ-Lactam analogues of penicillanic and carbapenicillanic acids (1983)

J. E. Baldwin, M. F. Chan, G. Gallacher, P. Monk and K. Prout, J. Chem. Soc., Chem. Commun., 1983, 250 DOI: 10.1039/C39830000250
The discovery of (2S,3S)-cis-2-(diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine as a novel, nonpeptide substance P antagonist. [Erratum to document cited in CA117(5):48289n] (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleThe discovery of (2S,3S)-cis-2-(diphenylmethyl)-N-[(2-methoxyphenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine as a novel, nonpeptide substance P antagonist. [Erratum to document cited in CA117(5):48289n]John A. Lowe III, Susan E. Drozda, R. Michael Snider, Kelly P. Longo, Stevin H. Zorn, Jean Morrone, Elisa R. Jackson, Stafford McLean, Dianne K. Bryce, and Cite this: J. Med. Chem. 1992, 35, 25, 4768Publication Date (Print):December 1, 1992Publication History Published online1 May 2002Published inissue 1 December 1992https://pubs.acs.org/doi/10.1021/jm00103a022https://doi.org/10.1021/jm00103a022research-articleACS PublicationsRequest reuse permissionsArticle Views46Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Effect of Copper on Expression of Functional Genes and Proteins Associated with Bradyrhizobium diazoefficiens Denitrification (2022)

Nitrous oxide (N<sub>2</sub>O) is a powerful greenhouse gas that contributes to climate change. Denitrification is one of the largest sources of N<sub>2</sub>O in soils. The soybean endosymbiont <i>Bradyrhizobium diazoefficiens</i> is a model for rhizobial denitrification studies since, in addition to fixing N<sub>2</sub>, it has the ability to grow anaerobically under free-living conditions by reducing nitrate from the medium through the complete denitrification pathway. This bacterium contains a periplasmic nitrate reductase (Nap), a copper (Cu)-containing nitrite reductase (NirK), a <i>c</i>-type nitric oxide reductase (cNor), and a Cu-dependent nitrous oxide reductase (Nos) encoded by the <i>napEDABC, nirK, norCBQD</i> and <i>nosRZDFYLX</i> genes, respectively. In this work, an integrated study of the role of Cu in <i>B. diazoefficiens</i> denitrification has been performed. A notable reduction in <i>nirK</i>, <i>nor,</i> and <i>nos</i> gene expression observed under Cu limitation was correlated with a significant decrease in NirK, NorC and NosZ protein levels and activities. Meanwhile, <i>nap</i> expression was not affected by Cu, but a remarkable depletion in Nap activity was found, presumably due to an inhibitory effect of nitrite accumulated under Cu-limiting conditions. Interestingly, a post-transcriptional regulation by increasing Nap and NirK activities, as well as NorC and NosZ protein levels, was observed in response to high Cu. Our results demonstrate, for the first time, the role of Cu in transcriptional and post-transcriptional control of <i>B. diazoefficiens</i> denitrification. Thus, this study will contribute by proposing useful strategies for reducing N<sub>2</sub>O emissions from agricultural soils.
High-performance advanced filter bank analog-to-digital converter for universal RF receivers (2002)

The advanced filter bank analog-to-digital converter (AFB ADC) is a breakthrough approach to very high-speed, high-resolution analog-to-digital conversion which improves the speed of conversion by up to six times the state-of-the-art by using a parallel array of individual converters (patent pending). The AFB ADC uses multirate filter bank signal processing to improve performance. Because of its unique architecture, the AFB ADC is continuously upgradeable as new analog-to-digital converter chips become available, thereby maintaining its performance advantage. This paper describes the architecture and provides hardware prototype results for a 12-bit, 80 MSa/s system for use in a universal, software-reconfigurable radio frequency (RF) receiver for cellular, satellite, or military communications. A 14-bit, 325 MSa/s system is currently being developed.
Supplementary Figure 1 from Using Digital Pathology to Understand Epithelial Characteristics of Benign Breast Disease among Women Undergoing Diagnostic Image-Guided Breast Biopsy (2023)

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Measurement of temperature and water vapor concentration at gas turbine combustor exit by Raman scattering (1999)

Raman scattering method is applied to the measurement of the temperature profile and the water vapor concentration profile at the exit of an actual gas turbine combustor. The temperature is determined by the intensity ratio of N{sub 2} Anti-Stokes to N{sub 2} Stokes. The water vapor concentration is obtained by the intensity ratio of H{sub 2}O Stokes to N{sub 2} Stokes. At first the accuracy can be assured and increased by the calibration test in the preliminary experiments. Then these measurements have been conducted in an actual can-type methane-fueled combustor of gas turbine. The test facilities are designed for making the optical measurement possible in the high pressure and high temperature condition using the structure of double windows. The results obtained here can prove that this optical method is useful for the application of measuring the temperature and the water vapor concentration in the actual gas turbine combustor.
Improving the broke recirculation strategy in a newsprint mill (2004)

HEET BREAKS are a major disturbance in the newsprint process and cause costly paper machine downtime. Fluctuations in the pulp furnish can upset the stability of a paper machine and are one of the causes of breaks. These fluctuations can be the result of the broke recirculation strategy applied at the mill. Specifically, sudden changes to the broke ratio can induce considerable variations in the properties of the mixed pulp at the paper machine headbox [7]. Broke recirculation strategies can be quantified and explored by the application of simulation-based optimization. This technique is increasingly being used in other applications, and has been shown to yield significant economic benefits at low investment cost and little disturbance to the actual process [3,6]. This study focuses on developing a dynamic simulation of the papermaking section of an integrated newsprint mill, and using an objective function to quantify fluctuations at the headbox. Direct search optimization was then applied to identify opportunities for improving the broke recirculation strategy at the mill. The overall goal was to reduce headbox variability caused by adjustments in the broke ratio.
EasyGuide™ Neuro, ein neues System zur bildgeführten Planung, Simulation und Navigation in der Neurochirurgie (1995)

Article EasyGuide™ Neuro, ein neues System zur bildgeführten Planung, Simulation und Navigation in der Neurochirurgie was published on January 1, 1995 in the journal Biomedical Engineering / Biomedizinische Technik (volume 40, issue s1).
Direct Access to Multifunctionalized Norcamphor Scaffolds by Asymmetric Organocatalytic Diels–Alder Reactions (2015)

Abstract A general organocatalytic cross‐dienamine activation strategy to produce chiral multifunctionalized norcamphor compounds having a large diversity in substitution pattern is presented. The strategy is based on a Diels–Alder reaction of an amino‐activated cyclopentenone reacting with most common classes of electron‐deficient olefins, such as nitro‐, ester‐, amide‐, and cyano‐substituted olefins, chalcones, conjugated malononitriles, CF 3 ‐substituted enones, and fumarates. The corresponding norcamphor derivatives are formed in good yield, excellent enantioselectivities, and with complete diastereoselectivity. Furthermore, it is demonstrated that quaternary stereocenters and spiro norcamphor compounds can be formed with high stereoselectivity. The present development provides a simple, direct, and efficient approach for the preparation of important norcamphor scaffolds.
The Features of the Stress-Reaction to Repetitive Nanosecond Microwave Pulses (2018)

The effect of nanosecond repetitive pulsed microwaves on the possibility of triggering a stress response of laboratory mice was investigated. The exposure was carried out every day once per a day during the 5 days' period (4000 pulses per session) with repetition rates of 8, 13, 16 and 22 pulses per second. The source of radiation was a laboratory pulse generator based on a magnetron MI-505 with a carrier frequency of 10 GHz, a pulse duration at half the power level of 100 ns, an output peak power of 180 kW, an electric field strength of 1.5 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> V/cm, a peak power density of 1.5 × 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> kW/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . It was found that repeated exposure alters the level of corticosterone in the blood serum. The effect depends on the frequency of repetition of microwave pulses. Possible mechanisms of the effect of radiation on the level of corticosterone are considered.
A MicroRNA Signature in Acute Coronary Syndrome Patients and Modulation by Colchicine (2020)

The levels of specific miRNAs elevated in ACS returned to levels similar to control individuals following colchicine. These miRNAs may mediate ACS (via inflammatory pathways) or increase post-ACS risk, and could be potentially used as biomarkers of treatment efficacy.
Architecture simplications for an improved performance RAKE receiver (2002)

A new architecture for a RAKE receiver using n samples per chip period is studied in order to find the best trade-off between the achievable performance and the complexity of a receiver for direct-sequence code division multiple access system for mobile radio. The architecture of this n-oversampled RAKE receiver is described as well as a means of reducing complexity based on a proper selection of the coefficients of the estimated channel impulse response. Simulation results on bit-error-rate (BER) at the output of the 4-oversampled RAKE as a function of E/sub s//N/sub o/ are presented for an indoor channel for binary phase shift keying (BPSK) and quadrature phase shift keying (QPSK). For comparison purposes, simulation results for two more conventional RAKE receivers using one sample per chip period and selecting either arbitrarily or dynamically the sampling instant are also given. For the 4-oversampled RAKE, significant reduction of the complexity with respect to the case of the processing of all paths is achieved.
Fetal Neuroprotective Strategies: Therapeutic Agents and Their Underlying Synaptic Pathways (2021)

Synaptic signaling is integral for proper brain function. During fetal development, exposure to inflammation or mild hypoxic-ischemic insult may lead to synaptic changes and neurological damage that impairs future brain function. Preterm neonates are most susceptible to these deleterious outcomes. Evaluating clinically used and novel fetal neuroprotective measures is essential for expanding treatment options to mitigate the short and long-term consequences of fetal brain injury. Magnesium sulfate is a clinical fetal neuroprotective agent utilized in cases of imminent preterm birth. By blocking N-methyl-D-aspartate receptors, magnesium sulfate reduces glutamatergic signaling, which alters calcium influx, leading to a decrease in excitotoxicity. Emerging evidence suggests that melatonin and N-acetyl-L-cysteine (NAC) may also serve as novel putative fetal neuroprotective candidates. Melatonin has important anti-inflammatory and antioxidant properties and is a known mediator of synaptic plasticity and neuronal generation. While NAC acts as an antioxidant and a precursor to glutathione, it also modulates the glutamate system. Glutamate excitotoxicity and dysregulation can induce perinatal preterm brain injury through damage to maturing oligodendrocytes and neurons. The improved drug efficacy and delivery of the dendrimer-bound NAC conjugate provides an opportunity for enhanced pharmacological intervention. Here, we review recent literature on the synaptic pathways underlying these therapeutic strategies, discuss the current gaps in knowledge, and propose future directions for the field of fetal neuroprotective agents.
Stationary Plasma Thruster Plume Emissions (1994)

The emission spectrum from a xenon plasma produced by a Stationary Plasma Thruster provided by the Ballistic Missile Defense Organization (BMDO) was measured. Approximately 270 individual Xe I, Xe II, and XE III transitions were identified. A total of 250 mW of radiated optical emission was estimated from measurements taken at the thruster exit plane. There was no evidence of erosion products in the emission signature. Ingestion and ionization of background gas at elevated background pressure was detected. The distribution of excited states could be described by temperatures ranging from fractions of 1 eV to 4 eV with a high degree of uncertainty due to the nonequilibrium nature of this plasma. The plasma was over 95 percent ionized at the thruster exit plane. Between 10 and 20 percent of the ions were doubly charged. Two modes of operation were identified. The intensity of plasma emission increased by a factor of two during operation in an oscillatory mode. The transfer between the two modes of operation was likely related to unidentified phenomena occurring on a time scale of minutes.
ChemInform Abstract: DIE ADDITION VON N‐CHLOR‐URETHANEN AN ENOLAETHER IN GEGENWART VON CR(II)‐CHLORID ALS KATALYSATOR, DIE SYNTHESE VON N‐ALKOXYCARBONYL‐DERIVATEN AUS 2‐AMINOZUCKERN SOWIE ALPHA‐AMINO‐KETONEN UND ‐ALDEHYDEN (1971)

Abstract Die beiden N‐Chlor‐urethane (IIa) und (IIb) reagieren mit Dihydropyran (I) in Methanol über die Zwischenstufen (III) zu den Addukten (IV)‐(VI).
On Parameter Estimation of Ricean Fading MIMO Channel: Correlated Signals and Spatial Scattering (2006)

The purpose of this paper is to account for estimating the MIMO channel parameters in the presence of stochastically correlated signals, spatial scattering and Ricean fading. A parametric framework based on the second-order statistic is developed herein. As manipulated a few of reduced parameterizations, we derive an explicit form of the array covariance matrix, an alternative expression of the Cramer-Rao bound (CRB), and two asymptotically efficient estimators. Numerical simulation is conducted to demonstrate the estimation possibility of three important parameters in wireless communication, such as the nominal direction, the angular spread and the generalized Rice factor. It appears that for a large number of temporal snapshots, the performance of both estimators can attain the CRB, while the asymptotic maximum likelihood estimator outperforms the weighted least squares criterion in non-asymptotic region.
Homogenous Iron-Catalysed Deuteration of Electron-Rich Arenes and Heteroarenes (2022)

Abstract Deuterated organic molecules are of interest for many applications ranging from mechanistic investigations in basic organic and physical chemistry to the development of new pharmaceuticals. Thus, methodologies for isotope-labelling reactions continue to be important. Here, a convenient methodology for hydrogen/deuterium exchange reactions in electron-rich arenes is reported using simple iron salts and deuterium oxide as isotope source.
Synthetic Inhibitors of DNA Topoisomerase I and II. (1999)

A new type of synthetic inhibitor of DNA topoisomerase I and II was examined and several of these derivatives exhibited strong dual activity against these enzymes. This series of compounds showed high cytotoxic activities against cancer cells, but only a limited number of compounds showed any noticeable activity in an in vivo test against murine P388. Non-specific toxicity was observed in the in vivo tests.
CAVER Analyst 1.0: graphic tool for interactive visualization and analysis of tunnels and channels in protein structures (2014)

CAVER Analyst is a multi-platform software written in JAVA. Binaries and documentation are freely available for non-commercial use at http://www.caver.cz.
Arabic Alphabets Sign Language Dataset (ArASL) (2018)

A new dataset consists of 54,049 images of ArSL alphabets performed by more than 40 people for 32 standard Arabic signs and alphabets. The number of images per class differs from one class to another. Sample image of all Arabic Language Signs is also attached. The CSV file contains the Label of each corresponding Arabic Sign Language Image based on the image file name.
Differences in the Impact of Pneumococcal Serotype Replacement in Individuals With and Without Underlying Medical Conditions (2018)

These findings could help to predict the impact of next-generation PCVs in specific risk groups.
Structurally embedded photoconductive silicon bowtie antenna (1998)

We report the generation of 1.5-3.0-GHz electromagnetic radiation by a photoconductive bowtie antenna in a continuous-wave (CW) mode. The semiconductor bowtie element was made of silicon, and activated by a semiconductor laser beam delivered through a novel light waveguide system. We observed for the first time of our knowledge the VSWR resonance and a near copper-performance (<5 dB) with the optical power density as low as 1.0 W/cm/sup 2/. Further reduction of the optical power requirement is possible and will be tentatively presented with the aim of achieving the goal of less than 0.1 W/cm/sup 2/.