gebhart/patrepeval huggingface dataset:
Cytogenetic Studies in Human Cells ExposedIn Vitroto GSM-900 MHz Radiofrequency Radiation Using R-Banded Karyotyping (2010)

It is important to determine the possible effects of exposure to radiofrequency (RF) radiation on the genetic material of cells since damage to the DNA of somatic cells may be linked to cancer development or cell death and damage to germ cells may lead to genetic damage in next and subsequent generations. The objective of this study was to investigate whether exposure to radiofrequency radiation similar to that emitted by mobile phones of second-generation standard Global System for Mobile Communication (GSM) induces genotoxic effects in cultured human cells. The cytogenetic effects of GSM-900 MHz (GSM-900) RF radiation were investigated using R-banded karyotyping after in vitro exposure of human cells (amniotic cells) for 24 h. The average specific absorption rate (SAR) was 0.25 W/kg. The exposures were carried out in wire-patch cells (WPCs) under strictly controlled conditions of temperature. The genotoxic effect was assessed immediately or 24 h after exposure using four different samples. One hundred metaphase cells were analyzed per assay. Positive controls were provided by using bleomycin. We found no direct cytogenetic effects of GSM-900 either 0 h or 24 h after exposure. To the best of our knowledge, our work is the first to study genotoxicity using complete R-banded karyotyping, which allows visualizing all the chromosomal rearrangements, either numerical or structural.
Photogrammetry and Remote Sensing (2002)

At last year"s ILMF meeting, three key issues facing the industry were noted: i) recruitment; ii) training; iii) development of standards and best practices.In 2004, the Applied Geomatics Research Group embarked on a market research
Mobility Prediction for Multimedia Services (2006)

Advances in technology have enabled a proliferation of mobile devices and a broad spectrum of novel and out breaking solutions for new applications and services. In the present, more and more people and companies are demanding mobile access to multimedia services such as real-time rich media. Today, it is necessary to be able to predict adaptation behaviour which concerns and addresses not only the mobile usage or the infrastructure availability, but the service quality especially the continuity of service. Our chapter provides insight to new challenges of mobile multimedia services and applications: Wifi indoor positioning system adapted to heterogeneous building, static and learning mobility prediction, predictive handover policy for multimedia cache management, mobile multimedia guide (such as museum), and network scalability.
Flexural Strengthening of Reinforced Concrete Beam- Column Joints Using Innovative Anchorage System (2017)

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2P021 Evaluation of protein complex model using molecular dynamics simulation with the solution theory in the energy representation(01A. Protein: Structure,Poster) (2013)

In order to understand the mechanism of hydrolysis of GTP in the Hras-GTP complex, we study the structures of Hras-GTP and GDP complexes in water solvent by molecular dynamics (MD) simulations. We evaluated the potential parameters and the atomic charges around Mg2+ in Hras-GTP and GDP complexes by quantum chemical calculations. We performed MD simulations of the Hras-GTP and GDP complexes in water solvent using parameters of AMBER03 and our parameters around Mg2+. We found that the angular distribution of water around GTP is different from the distribution around GDP. We proposed that this difference of causes the difference of hydrolyzability between GTP and GDP.
Verification-Purpose Operating System for Microprocessor System-Level Functions (2010)

Microprocessor system-level functions that provide hardware support for software are difficult to verify on FPGA prototypes. Traditional FPGA verification involves running a general-purpose operating system such as Linux. However, such a GPOS is difficult to control, and debug is inefficient. The verification-purpose operating system, on the other hand, simplifies debug and is easy to control. VPOS also significantly increases coverage over that of GPOS approaches.
Cryogenic Hydrogen System for a Spallation Neutron Source in J-PARC (2008)

Through the collaboration of the Japan Atomic Energy Agency and High Energy Accelerator Research Organization, the Japan Proton Accelerator Research Complex (J-PARC) has been constructed. The prime purpose is to use the various secondary particle beams such as neutrons, mesons and neutrinos produced in proton-nucleus reactions. One of the facilities that has already been completed is a materials and life-science experimental facility (MLF) where materials and biological structures are analyzed by neutron beam-scattering experiments. In the MLF, a spallation neutron source that provides a high-intensity pulse neutron with low-order meV energy for scattering experiments has been completed, and has successfully produced the desired neutrons. Neutrons produced by spallation reaction have high-order MeV energy, and the high-energy neutron is then transformed to meV-order energy by passing it through a supercritical hydrogen moderator. Therefore, a cryogenic hydrogen system is equipped in the spallation neutron source system. This paper describes the first operation results of the cryogenic hydrogen system.
Formation of N‐Pyroglutamyl Peptides from N‐Glu andN‐Gln Precursors in Aplysia Neurons (1999)

Matrix-assisted laser desorption/ionization with time-of-flight mass spectrometry is used to examine the formation of N-pyroglutamate (pGlu) in single, identified neurons from Aplysia. Six pGlu peptides are identified in the R3-14 and the R15 neurons that result from in vivo processing of peptides containing either Glu or Gln at their respective N-termini. Moreover, we show that Glu-derived pGlu is not a sample collection or measurement artifact. The pGlu peptides are detected in isolated cell bodies, regenerated neurites in culture, interganglionic connective nerves, cell homogenates, and collected releasates. We also demonstrate that R3-14 cells readily convert a synthetic N-Glu peptide to its pGlu analogue, indicating the presence of novel enzymatic activity.
Enhancing the Output Performance of Triboelectric Nanogenerator via Grating‐Electrode‐Enabled Surface Plasmon Excitation (2019)

Abstract The surface charge density and the output impedance of triboelectric nanogenerators (TENGs) are two critical factors for TENGs to speed up their commercialization, so it is important to explore unique methods to reduce the output impedance and increase the surface charge density. Here, an approach is demonstrated to effectively boost the output performance of TENG while reducing the output impedance of TENGs by utilizing grating‐electrode‐enabled surface plasmon excitation. A sustainable and enhanced output performance of about 40 µA (short‐circuit current) and 350 V (peak‐to‐peak voltage at a resistance of 10 MΩ) is produced via grating‐coupled surface plasmon resonance on the TENG with the aluminum grating electrode in the line density of 600 lines mm −1 , and it delivers a peak output power of 3.6 mW under a loading resistance of 1 MΩ, giving over 4.5‐fold enhancement in output power and a 75% reduction in the output impedance. Finally a self‐powered ultrasonic ranging system is utilized to verify the capability of the TENG in powering portable electrics.
Formation and Physical Properties of Yogurt (2010)

Yogurt gels are a type of soft solid, and these networks are relatively dynamic systems that are prone to structural rearrangements. The physical properties of yogurt gels can be qualitatively explained using a model for casein interactions that emphasizes a balance between attractive (e.g., hydrophobic attractions, casein cross-links contributed by calcium phosphate nanoclusters and covalent disulfide cross-links between caseins and denatured whey proteins) and repulsive (e.g., electrostatic or charge repulsions, mostly negative at the start of fermentation) forces. Various methods are discussed to investigate the physical and structural attributes of yogurts. Various processing variables are discussed which influence the textural properties of yogurts, such as total solids content, heat treatment, and incubation temperatures. A better understanding of factors contributing to the physical and structural attributes may allow manufacturers to improve the quality of yogurt.
Pancreatic Cystic Neoplasms: Imaging Surveillance for Pancreatic and Extra-Pancreatic Malignancy (2009)

Matsushita, Mitsunobu MD; Ikeura, Tsukasa MD; Shimatani, Masaaki MD; Uchida, Kazushige MD; Takaoka, Makoto MD; Nishio, Akiyoshi MD; Okazaki, Kazuichi MD Author Information
Plasmonic crystal based solid substrate for biomedical application of SERS (2014)

Surface Enhanced Raman Spectroscopy is a powerful analytical technique that combines the excellent chemical specificity of Raman spectroscopy with the good sensitivity provided by the enhancement of the signal observed when a molecule is located on (or very close to) the surface of suitable nanostructured metallic materials. The availability of cheap, reliable and easy to use SERS substrates would pave the road to the development of bioanalytical tests that can be used in clinical practice. SERS, in fact, is expected to provide not only higher sensitivity and specificity, but also the simultaneous and markedly improved detection of several targets at the same time with higher speed compared to the conventional analytical methods. Here, we present the SERS activity of 2-D plasmonic crystals made by polymeric pillars embedded in a gold matrix obtained through the combination of soft-lithography and plasma deposition techniques on a transparent substrates. The use of a transparent support material allowed us to perform SERS detection from support side opening the possibility to use these substrates in combination with microfluidic devices. In order to demonstrate the potentialities for bioanalytical applications, we used our SERS active gold surface to detect the oxidation product of apomorphine, a well-known drug molecule used in Parkinson’s disease which has been demonstrated being difficult to study by traditional HPLC based approaches.
High definition cardiac perfusion PET using a new F-18 imaging agent (BMS747158) (2010)

151 Objectives HD-PET technology improves spatial resolution and signal-to-noise on reconstructed PET images (IEEE TMI 2006:25:7:907-921) but the thermal path of the positron emitted by rubidium limits its benefits in Rb-82 perfusion images. To evaluate its full potential for high-resolution cardiac imaging, we evaluated HD-PET with myocardial perfusion images obtained with a new F-18 based agent (BMS-747158). Methods Images of 15 patients recruited at Cedars-Sinai Medical Center as part of the Phase II clinical trial for a new F-18 perfusion agent were acquired on a 4-ring Siemens Biograph-64. Static and 8-bin ECG-gated images were generated using standard reconstruction (SR - 2D Attenuation Weighted Ordered Subsets Expectation Maximization) and HD-PET. We computed the wall/cavity contrast and contrast-to-noise ratio (CNR), and maximum to defect contrast. Wall thickness at three different levels of heart (basal, mid, apical), wall motion, wall thickening and ejection fraction (EF) were also estimated with automatic quantification. Results HD-PET showed significant contrast change compared to SR (+32.3±17.9%, p Conclusions Perfusion studies with a new F-18 agent show significantly improved image resolution, contrast and contrast-to-noise with HD-PET reconstruction as compared with the standard reconstruction technique
Asymmetric bagging and random subspace for support vector machines-based relevance feedback in image retrieval (2006)

Relevance feedback schemes based on support vector machines (SVM) have been widely used in content-based image retrieval (CBIR). However, the performance of SVM-based relevance feedback is often poor when the number of labeled positive feedback samples is small. This is mainly due to three reasons: 1) an SVM classifier is unstable on a small-sized training set, 2) SVM's optimal hyperplane may be biased when the positive feedback samples are much less than the negative feedback samples, and 3) overfitting happens because the number of feature dimensions is much higher than the size of the training set. In this paper, we develop a mechanism to overcome these problems. To address the first two problems, we propose an asymmetric bagging-based SVM (AB-SVM). For the third problem, we combine the random subspace method and SVM for relevance feedback, which is named random subspace SVM (RS-SVM). Finally, by integrating AB-SVM and RS-SVM, an asymmetric bagging and random subspace SVM (ABRS-SVM) is built to solve these three problems and further improve the relevance feedback performance.
Design, Simulation and Fabrication of A Novel MEMS Based Pulsometer (2018)

A novel pulsometer was successfully developed using microelectromechanical systems (MEMS) based silicon-on-glass (SOG) technology for biomedical applications. The sensor was modelled and simulated in COMSOL Multiphysics for pressures ranging from 0 to 40 mmHg. The capability of the fabricated pulsometer to detect movements in x and z-axis directions was investigated. The simulation results demonstrated displacement changes as high as of 98% and 36% in the x and z-axis directions, respectively for 40 mmHg, which correspond to typical radial blood pressure (rBP) on the wrist. In addition, an average capacitance change of 1 nF was experimentally obtained in the x-axis direction, from -5 V to 5 V. The response of the pulsometer is analyzed and presented in this paper.
Evidence that extracellular components function in adherence of Actinobacillus actinomycetemcomitans to epithelial cells (1993)

Extracellular microvesicles and a highly proteinaceous polymer associated with a leukotoxin-producing strain, Actinobacillus actinomycetemcomitans SUNY 75, were shown to increase adherence of other weakly adherent A. actinomycetemcomitans strains to KB epithelial cells.
Current Status of Metal–Organic Framework Membranes for Gas Separations: Promises and Challenges (2011)

Metal–organic frameworks (MOFs) are hybrid organic–inorganic nanoporous materials that exhibit regular crystalline lattices with relatively well-defined pore structures. Chemical functionalization of the organic linkers in the structures of MOFs affords facile control over pore size and chemical/physical properties, making MOFs attractive for a variety of industrial applications including membrane-based gas separations. A wealth of reports exists discussing the synthesis and applications of MOFs; however, relatively few reports exist discussing MOF membranes. This disparity owes to challenges associated with fabricating films of MOF materials, including poor substrate–film interactions, moisture sensitivity, and thermal/mechanical instability. Since even nanometer-scale cracks and defects can affect the performance of a membrane for gas separation, these challenges are particularly acute for the fabrication of MOF membranes. Here, we review recent progress on MOF membranes with an emphasis on their fabrication techniques, challenges involved in membrane synthesis, reported strategies to address these challenges (issues), and gas separation performance. Finally, we conclude with our perspectives on future research directions in this area.
Immune Checkpoint Inhibitors for Non-Small-Cell Lung Cancer with Brain Metastasis : The Role of Gamma Knife Radiosurgery (2020)

GKS with ICI showed no favorable OS outcome in treating brain metastasis from NSCLC. However, GKS with ICI did not increase the risk of complications. Furthermore, compared with ICI alone, GKS with ICI may be associated with a reduced incidence of LMS. Further understanding of the mechanism, which remains unknown, may help improve the quality of life of patients with brain metastasis.
Comments on orbital steering (2009)

Molecular orbital theory has been applied to explore the potential energy surface for several bimolecular reactions. The results of these calculations can be used to assess the rate accelerations that might be achieved in similar optimally oriented reactions. Several of the reactions studied (e.g., CH3O− + H2NCHO) are bimolecular counterparts of intermediate steps in enzyme catalysis (e.g., serine proteinase activity). In these cases the importance of “orbital steering” as a vehicle for enzyme catalysis is assessed.
127 ESTIMATION OF TIEXPONENTIAL COMPONENTS IN T2 RELAXATION USING ALAN R. BLEIER (1986)

SANDCR, TAMAS; JOLESZ, FERENC A.; RUENZEL, PAUL W.; Adams, Douglass F. Author Information
Pathophysiologie, évaluation et traitement médical de l’incontinence fécale (2002)

L’incontinence fécale est un problème fréquent en pratique médicale mais souvent sous-estimé et mal traité. Cet artiele revoit l’épidémiologie, les mécanismes pathophysiologiques et les approaches diagnostiques des patients souffrant d’incontinence fécale. De plus, je ferai une synthèse des traitements médicaux de l’incontinence fécale. Une anamnèse systématique et une étude de la morphologie et de la physiologie anorectales permet souvent de mettre en évidence les mécanismes pathogéniques sous-jacents et d’orienter le traitement.
Commutation Torque Ripple Reduction in Brushless DC Motor Drives Using a Single DC Current Sensor (2004)

This paper presents a comprehensive study on reducing commutation torque ripples generated in brushless DC motor drives with only a single DC-link current sensor provided. In such drives, commutation torque ripple suppression techniques that are practically effective in low speed as well as high speed regions are scarcely found. The commutation compensation technique proposed here is based on a strategy that the current slopes of the incoming and the outgoing phases during the commutation interval can be equalized by a proper duty-ratio control. Being directly linked with deadbeat current control scheme, the proposed control method accomplishes suppression of the spikes and dips superimposed on the current and torque responses during the commutation intervals of the inverter. Effectiveness of the proposed control method is verified through simulations and experiments.
Experimental investigation of thermal conductivity coefficient and heat exchange between fluidized bed and inclined exchange surface (2009)

The paper presents experimental research of thermal conductivity coefficients of the siliceous sand bed fluidized by air and an experimental investigation of the particle size influence on the heat transfer coefficient between fluidized bed and inclined exchange surfaces. The measurements were performed for the specific fluidization velocity and sand particle diameters d p=0.3, 0.5, 0.9 mm. The industrial use of fluidized beds has been increasing rapidly in the past 20 years owing to their useful characteristics. One of the outstanding characteristics of a fluidized bed is that it tends to maintain a uniform temperature even with nonuniform heat release. On the basis of experimental research, the influence of the process's operational parameters on the obtained values of the bed's thermal conductivity has been analyzed. The results show direct dependence of thermal conductivity on the intensity of mixing, the degree of fluidization, and the size of particles. In the axial direction, the coefficients that have been treated have values a whole order higher than in the radial direction. Comparison of experimental research results with experimental results of other authors shows good agreement and the same tendency of thermal conductivity change. It is well known in the literature that the value of the heat transfer coefficient is the highest in the horizontal and the smallest in the vertical position of the heat exchange surface. Variation of heat transfer, depending on inclination angle is not examined in detail. The difference between the values of the relative heat transfer coefficient between vertical and horizontal heater position for all particle sizes reduces by approximately 15% with the increase of fluidization rate.
Supplementary Figure from Covalent ERα Antagonist H3B-6545 Demonstrates Encouraging Preclinical Activity in Therapy-Resistant Breast Cancer (2023)

Supplementary Figure from Covalent ERα Antagonist H3B-6545 Demonstrates Encouraging Preclinical Activity in Therapy-Resistant Breast Cancer
Monolithic laser integrated Mach-Zehnder modulator InP PICs for high-speed optical networks (2016)

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Nanomechanical analysis of bone tissue engineering scaffolds (2006)

Copolymers of (2-hydroxyethyl methacrylate) (HEMA) and methacrylamide monomers conjugated with amino acids were synthesized and crosslinked with ethylene glycol dimethacrylate. The resulting library of copolymers was mineralized in vitro using two distinct methods. In the first mineralization method, the copolymers were polymerized in the presence of a sub-micron hydroxyapatite (HA) suspension. In the second method, copolymers were mineralized with HA using a urea-mediated process. The mechanical properties of all of the copolymers, both mineralized and not, were determined using nanoindentation under both load and displacement control. A power law fit to the initial unloading curve was used to determine a reduced elastic modulus for each material. Between 30 and 300 indentations were performed on each material, and ANOVA analysis was run to determine the statistical significance of differences in modulus between samples. Using nanoindentation, the 22 different samples had reduced modulus values ranging from 840 MPa to 4.14 GPa. Aspartic acid-methacrylate (Asp-MA) copolymers were not distinguishable from the pHEMA control material. Polymerization in the presence of HA created a more uniform material than the urea method of mineralization. Several challenges and solutions encountered in the nanomechanical testing of soft, heterogeneous materials are discussed. These results demonstrate that with proper experimental design, the mechanical properties of tissue engineering scaffold materials based on polymer-ceramic composite materials can be determined using small samples and nanoindentation techniques.
Indicizzazione di sequenze video attraverso l'analisi dell'audio sottostante (2000)

In questo lavoro viene proposto un approccio innovativo all'indicizzazione di sequenze video basato sull'analisi dello stream audio sottostante. I metodi implementati permettono di segmentare l'audio in un insieme di classi immagine con elevato contenuto semantico. Ciò consente di individuare situazioni altamente significative solamente informazioni estratte attraverso l'elaborazione del segnale audio. Per far questo è stato sviluppato un algoritmo di segmentazione dell'audio in quattro classi omogenee (silenzio, voce, musica, rumore) basato sull'analisi di semplici caratteristiche temporali e frequenziali.
Wavelength stabilized single-mode lasers by coupled micro-square resonators (2003)

Wavelength stabilized single-mode lasers were realized by on-chip coupling of a ridge waveguide laser with two micro-ring resonators. The micro-ring resonators were fabricated by deeply etching to achieve high lateral optical confinement and to allow small ring diameters in the range between 20-60 μm. A square-like ring geometry with 45/spl deg/ facets was used to improve design control and side-wall quality. By using micro rings with two different diameters of 50 and 60 μm, a free spectral range of about 18 nm could be obtained which allow a stable single-mode operation with a side-mode suppression ratio of more than 40 dB and a continuous-wave output power of 30 mW per facet at room temperature.