gebhart/patrepeval huggingface dataset:
Biomechanics of the Ageing Foot and Ankle: A Mini-Review (2014)

Foot pain is highly prevalent in older people and has a significant detrimental impact on mobility and quality of life. In recent years, there has been increased interest in exploring the biomechanical factors that may contribute to the development of foot disorders and the associated impairment of mobility in this age group. Studies have shown that with advancing age, there is a general tendency for the foot to exhibit increased soft tissue stiffness, a decreased range of motion, decreased strength and a more pronated posture as well as to function in a more pronated position with reduced joint mobility and less efficient propulsion when walking. These changes may contribute to the development of foot pain, impair performance in functional weight-bearing activities and increase the risk of falls. However, plantar pressure analysis technology has considerable potential to assist in optimising the design of interventions to redistribute load away from high-pressure areas, thereby alleviating foot symptoms and improving mobility in older people.
White Matter Injury After Subarachnoid Hemorrhage (2015)

SAH causes BBB disruption and consequent injury in white matter. MMP-9 plays an important role in those pathologies and could be a therapeutic target for SAH-induced white matter injury.
Effect of SiO<sub>2</sub> and SiO<sub>2</sub>/SiN<sub><italic>x</italic></sub> Passivation on the Stability of Amorphous Indium-Gallium Zinc-Oxide Thin-Film Transistors Under High Humidity (2015)

We studied the environmental stability of amorphous indium-gallium-zinc-oxide (a-IGZO) thin-film transistors (TFTs) with single-layer (SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> ) and bilayer (SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> /SiN <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</sub> ) passivation under high-humidity (80%) storage. During the 30 days of investigation, all single-layer passivated TFTs showed negative turn-ON voltage shifts (AVON), the size of which increased with storing time. The negative A VON is attributed to donor generation inside the active a-IGZO caused by the diffusion of ambient hydrogen/water molecules passing through the SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> passivation layer. The X-ray photoelectron spectroscopy depth profile for the SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> passivated structures confirms that the concentration of oxygen vacancies, which is initially larger at the a-IGZO/SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> interface, compared with the bulk a-IGZO, decreases after 30 days of storage under high humidity. This can be explained as the passivation of oxygen vacancies by diffused hydrogen. On the other hand, all bilayer passivated TFTs showed good air stability at room temperature and high humidity (80%).
Superanalysis of Optimum Combining with Application to Femtocell Networks (2012)

A femtocell technology-towards the deployment of small-cell networks-is a key enabler for improving indoor coverage and throughput per network area at a low cost in future wireless networks. However, these small-cell networking inevitably increases cochannel interference due to aggressive (even uncontrolled) reuse of spectral resources. One of the attractive approaches to alleviating the cochannel interference is a multiple-antenna technique for which accurately characterizing the effects of interference is crucial but challenging. To elucidate this important problem, we analyze the performance of interference rejection diversity combining, often called the optimum combining, in an uplink two-tier femtocell network. Specifically, we consider that a single-antenna femtocell user (transmitter) communicates with a closed femtocell access point (receiver) with multiple antennas in the presence of single-antenna cochannel interferers from co-tier (femtocells) and cross-tier (macrocell) networks. We introduce a new mathematical methodology to analyze the average symbol error probability of optimum combining diversity systems in Rayleigh fading, accounting for multiple unequal-power interferers, each is spatially correlated across receiving antennas. The analysis resorts to the so-called Berezin's supermathematics that treats both commuting and Grassmann anticommuting variables on an equal footing. This powerful supermathematical framework enables us to quantify the cross- and co-tier interference effects in terms of interference power heterogeneity and spatial correlation.
Effects of a Take‐Home Drug Prevention Program on Drug‐Related Communication and Beliefs of Parents and Children (1991)

Five hundred and eleven fourth, fifth, and sixth grade students and their parents from six schools in northwest Arkansas participated in this study. Students were blocked on school and grade level, then assigned randomly by class to either the intervention Keep A Clear Mind (KACM) program or a waiting list control. KACM students received four weekly correspondence lessons designed to be completed at home with a parent. KACM students reported significantly less perceived peer use of alcohol, tobacco, and marijuana, as well as significantly less peer pressure susceptibility to experiment with cigarettes. Mothers in the KACM program reported significantly more recent and frequent communication with their children about refusing drugs, and significantly greater discussions with their children regarding how to resist peer pressure to use alcohol, tobacco, and marijuana. Intervention program fathers reported significantly more communication with their children concerning how to resist peer pressure to drink alcohol and use tobacco, and significantly greater motivation to help their children avoid drug use. No significant differences were found between groups on student intentions to use drugs. These data suggest a print medium that emphasizes parent-child activities holds promise for accessing families and enhancing drug prevention communication.
Method of Resource Estimation Based on QoS in Edge Computing (2018)

With the development of Internet of Things, the number of network devices is increasing, and the cloud data center load increases; some delay‐sensitive services cannot be responded to timely, which results in a decreased quality of service (QoS). In this paper, we propose a method of resource estimation based on QoS in edge computing to solve this problem. Firstly, the resources are classified and matched according to the weighted Euclidean distance similarity. The penalty factor and Grey incidence matrix are introduced to correct the similarity matching function. Then, we use regression‐Markov chain prediction method to analyze the change of the load state of the candidate resources and select the suitable resource. Finally, we analyze the precision and recall of the matching method through simulation experiment, validate the effectiveness of the matching method, and prove that regression‐Markov chain prediction method can improve the prediction accuracy.
Glycotranscriptome study reveals an enzymatic switch modulating glycosaminoglycan synthesis during B‐cell development and activation (2011)

B-cell fate and responses are modulated by soluble mediators and direct cellular interactions. Migration properties also vary during differentiation, commitment and activation. In many cells, modulation of responses to stimuli involves cell surface glycans, whose architecture depends on the simultaneous expression of multiple enzymes. By looking at the glycosylation-related gene expression patterns among B-cell populations, we determined in this study that the strongest variations were observed for CSGalNAcT-1 and EXTL1. These are enzymes involved in the biosynthesis of alternative forms of glycosaminoglycans (GAGs), namely chondroitin sulfate and heparan sulfate, respectively. These two enzymes showed inverse fluctuations in progenitors, resting B cells and activated B cells, suggesting a developmentally regulated switch between chondroitin and heparan sulfate synthesis. To explore whether these variations contributed to optimal B-cell differentiation, we overexpressed EXTL1 in the B-cell lineage of transgenic mice, yielding a partial differentiation blockade at the pro-B to pre-B transition. In the periphery, this defect was almost fully compensated for in vivo, with normal-size B-cell compartments and normal serum immunoglobulin levels in the transgenic EXTL1 mice. The peripheral B cells from EXTL1 transgenics were only affected with regard to their in vitro responses to polyclonal activation, showing reduced proliferation. Together the data suggest that despite their low amounts in lymphocytes, the heparan sulfate chains decorating the endogenous GAGs appear to be regulators of B-cell physiology.
Synthesis and Electronic Structure of Reduced Bis(imino)pyridine Manganese Compounds (2011)

Abstract The synthesis and electronic structure of reduced aryl‐substituted bis(imino)pyridine manganese compounds have been explored. Stirring a THF slurry of [( iPr PDI)MnCl 2 ] { iPr PDI = 2,6‐(2,6‐ i Pr 2 –C 6 H 3 N=CMe) 2 C 5 H 3 N} with excess Na and catalytic (0.5 mol‐%) naphthalene furnished the bis(THF) compound [( iPr PDI)Mn(THF) 2 ]. Performing the reduction with excess Na(Hg) in toluene furnished the bis(chelate) manganese compound [( iPr PDI) 2 Mn]. For both compounds, a combination of EPR spectroscopy, magnetic measurements and metrical parameters determined from X‐ray diffraction established high‐spin Mn II compounds with reduced, redox‐active bis(imino)pyridine ligands. Substitution of the THF ligands with carbon monoxide yielded [( iPr PDI)Mn(CO) 2 ], a low‐spin Mn I , d 6 compound with an experimentally observed bis(imino)pyridine‐centred radical. Oxidation and reduction of this compound furnished [( iPr PDI)Mn(CO) 3 ] + and [( iPr PDI)Mn(CO) 2 ] – , respectively, and provided a series of three manganese carbonyl compounds over three oxidation states. Elucidation of the electronic structure of these compounds established that oxidation events within the series are ligand‐ rather than manganese‐based, most likely a result of the stable low‐spin Mn I , d 6 electron configuration imparted by the strong‐field carbonyl ligands.
Time-Dependent Fracture-Interference Effects in Pad Wells (2014)

Summary Hydraulic fracturing in shale formations induces microseismic events in a region we refer to as the microseismic volume. Many of these microseismic events are signatures of failure in the formation that are believed to be a result of induced unpropped (IU) fractures beyond the primary propped fracture. Areally extensive microseismicity may be evidence that these IU fractures occur and extend spatially beyond the propped fracture during pumping in many unconventional reservoirs. We present evidence that these fractures close over time after pumping is stopped and that this closure of IU fractures can have a significant impact on stress interference between fractures. To illustrate these effects, microseismic and radioactive-tracer data are presented for four laterals drilled and fractured from a single pad. Two wells on this pad were fractured with the consecutive-fracturing sequence, and the other two wells were fractured with the zipper-fracturing sequence. Geomechanical simulations were performed to model the pad scenario and explain the microseismic and tracer observations, with emphasis on the two different fracturing sequences. Our simulations show that the opening of the IU fractures results in significant temporary changes to the stress field in the rock. One consequence of this is that later fracture stages tend to propagate into the open-fracture networks of IU fractures created earlier because of stress reorientation. This can lead to inefficient usage of fluid, proppant, and capital because the region that is being stimulated has already been stimulated by the previous stage. By analyzing the net pressure, radioactive-tracer data, and microseismic data from the four-well pad, we show that these IU fractures close over time because the fracture fluid leaks off. This reduces the stress shadow, and subsequent induced fractures are no longer subjected to the significantly altered stresses, allowing for more-efficient fracture-network coverage by subsequent fractures in a horizontal well. On the basis of the data presented and computer simulations, we propose the idea of maximizing the time between fracturing in the microseismic volume of a recently fractured region (within operational constraints). The time required for the IU fractures to close can be estimated from our models and varies on the basis of the reservoir and fluid properties from several hours to days. One example of how this is accomplished in practice is zipper fractures. However, our work suggests that there also may be other fracture-sequencing strategies for accomplishing this.
Binding of Staphylococcus aureus by human serum spreading factor in an in vitro assay (1986)

Human serum spreading factor, an animal cell adhesion-promoting glycoprotein, bound Staphylococcus aureus in an assay in which association of bacteria to protein-precoated microtiter wells was quantitated. Interaction of human serum spreading factor with S. aureus suggests that this protein may play a role in host defenses and in the invasiveness and pathogenicity of microbial infections.
Applications of Automated High Resolution Strain Mapping in TEM on the Study of Strain Distribution in MOSFETs (2014)

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Additional enhancement in surface-enhanced Raman scattering due to excitation geometry (2011)

It is well known that surface-enhanced Raman scattering (SERS) substrates based on metal island films exhibit higher levels of enhancement when excited through a transparent base material than when excited directly through air. However, to our knowledge, the origin of this enhancement has never been satisfactorily explained. An initial suggestion that the additional enhancement was due to a 'nearest layer effect' cannot account for the observation of additional enhancement for monolayer adsorbates. In this paper, finite difference time domain (FDTD) modelling is presented to show that the electric field intensity in between metal particles at the interface is higher for 'far-side' excitation. This is reasonably consistent with the observed enhancement for silver islands on SiO2. The modelling results are in agreement with a simple physical model based on Fresnel reflection at the interface. This suggests that the additional enhancement is due to a near-field enhancement of the electric field due to the phase shift at the dielectric interface, when the light passes from the higher to the lower region of refractive index.
Comparing the Characteristics of Microglia Preparations Generated Using Different Human iPSC-Based Differentiation Methods to Model Neurodegenerative Diseases (2022)

As the resident immune cells of the healthy nervous system, homeostatic microglia can rapidly become activated in response to injury/disease. Dysregulated microglia activation is a hallmark of nervous system disorders including neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and Alzheimer's disease. The elucidation of the biological and pathological roles of microglia has recently benefitted from the development of microglia-like cells using human induced pluripotent stem cell (iPSC)-based approaches. The success of iPSC-derived microglia preparations as a disease-relevant model system depends on their representation of the <i>in vivo</i> spatial and temporal heterogeneity of microglia under pathological conditions. Little is currently known about the potential of human iPSC-derived microglia generated using different methods for the study of neurodegenerative diseases. We compared the transcriptomes of human iPSC-derived microglia generated using two frequently used <i>in vitro</i> differentiation methods to determine whether separate strategies can generate microglia with distinct transcriptional signatures <i>in vitro</i>. We show that microglia derived using different differentiation methods display distinct maturation characteristics after equivalent times in culture. We also reveal that iPSC-derived microglia preparations generated using these two methods are composed of different subpopulations with transcriptomic signatures resembling those of <i>in vivo</i> regionally distinct microglia subtypes, specifically white-matter and gray-matter microglia. These findings highlight the need to better characterize the subtype composition of each microglia preparation prior to its use to model neurodegenerative diseases.
Development of novel surface modified poly (vinylidene fluoride ‐ co ‐ hexafluoropropylene) (PVDF ‐ HFP) membrane contactor for CO2 absorption (2016)

The ever increasing industrial activities worldwide are the ma in culprits for the greenhouse gases like carbon dioxide (CO 2 ) that cause global warming. Various methods were suggested to curb the production of CO2 , and the latest technology is the utilization of the flexibility of membranes in gas-liquid contactors. The principal aim of this study is to fabricate a surface modified poly (vinylide ne fluoride-co-hexafluoropropylene) (PVDF-HFP) by blending surface modifying macromolecules (SMM) in the polymer dope. Lithium chloride ( LiCl) was employed as pore-forming agent. The surface modified PVDF-HFP showed large pore size, higher effective surface porosity and overall porosity, critical water entry pressure and contact angle than plain PVDF-HFP. Moreoever, the surface modified PVDF-HFP showed a maximum CO 2 flux of 6.74 x 10 -4 mol/m 2 .s, which was nearly 38% higher than that of the control plain PVDF-HFP.
Co-editors’ Messages (2010)

1. Bernard Nusbaum, MD (drnusbaum{at}yahoo.com) 1. Coral Gables, Florida </br>![][1]</img> It seems that, within our ranks, the original skeptics of low level laser therapy (LLLT) (including myself) are gradually jumping the fence and recognizing that there may be, in fact, a beneficial
A mouse model of heart failure with preserved ejection fraction due to chronic infusion of a low subpressor dose of angiotensin II (2015)

Heart failure (HF) with preserved ejection fraction (HFpEF) is a clinical syndrome of HF symptoms associated with impaired diastolic function. Although it represents ∼50% of patients with HF, the mechanisms of disease are poorly understood, and therapies are generally ineffective in reducing HF progression. Animal models of HFpEF not due to pressure or volume overload are lacking, therefore limiting in-depth understanding of the pathophysiological mechanisms and the development of novel therapies. We hypothesize that a continuous infusion of low-dose angiotensin II (ATII) is sufficient to induce left ventricular (LV) diastolic dysfunction and HFpEF, without increasing blood pressure or inducing LV hypertrophy or dilatation. Osmotic pumps were implanted subcutaneously in 8-wk-old male mice assigned to the ATII (0.2 mg·kg(-1)·day(-1)) or volume-matched vehicle (N = 8/group) for 4 wk. We measured systolic and diastolic arterial blood pressures through a tail-cuff transducer, LV dimensions and ejection fraction through echocardiography, and LV relaxation through pulsed-wave Doppler and LV catheterization. Myocardial fibrosis and cardiomyocyte cross-sectional area were measured. ATII infusion had no effects on systemic arterial blood pressure. ATII induced significant impairment in LV diastolic function, as measured by an increase (worsening) in LV isovolumetric relaxation time, myocardial performance index, isovolumetric relaxation time constant, and LV end-diastolic pressure without altering LV dimensions, mass, or ejection fraction. Chronic infusion of low-dose ATII recapitulates the HFpEF phenotype in the mouse, without increasing systemic arterial blood pressure. This mouse model may provide insight into the mechanisms of HFpEF.
Research on Flower Image Classification Based on Transfer Learning (2023)

Due to the high similarity between flowers, it is difficult to identify them if they do not have the corresponding biological knowledge when classifying varieties manually. Given the above problems, to improve the accuracy and efficiency of flower classification, this paper proposes a migration parameter pre-training and fine-tuning VGG16 model based on the ImageNet data set to solve this problem. In this paper, the grid coverage enhancement method enhances the flower classification data set to expand the training sample data. The model uses the migration learning pre-training and fine-tuning method to improve network stability and accelerate network convergence. The results of comparative experiments show that the performance of the improved model has been significantly improved, and the result is better on the flower image data set, which has specific practical value.
Neutralization kinetics for polonium-218 [Erratum to document cited in CA108(24):210537e] (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNeutralization kinetics for polonium-218 [Erratum to document cited in CA108(24):210537e]Kai Dee Chu and Philip K. HopkeCite this: Environ. Sci. Technol. 1989, 23, 3, 368Publication Date (Print):March 1, 1989Publication History Published online1 May 2002Published inissue 1 March 1989https://pubs.acs.org/doi/10.1021/es00180a017https://doi.org/10.1021/es00180a017research-articleACS PublicationsRequest reuse permissionsArticle Views29Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts