gebhart/patrepeval huggingface dataset:
A New Maximum Power Tracking Method of Photovoltaic Power Generator Taking Frequency Characteristics of Solar Cell Module into Consideration. (1992)

Photovoltaic power can be generated even in small size installation, In a residential photovoltaic system the solar cell module array is mounted on the roof. In this case the controller for the maximum power tracking is required to be compact because the space of the control installation is not easily obtainable. For this reason the development of the high frequency operating controller is essential. However the e-i characteristics of the solar array at the frequency have hysteresis. In such frequency region the conventional controller based on no hysteresis can not be responsible for control of the power system. Therefore, it is necessary to develop a now control method to track the maximum power point of the solar array at the high frequency.
A measurement laboratory on geographic network for remote test experiments (2000)

A remote laboratory for teaching purposes in the field of measuring experiments was activated. Students can access automatic measuring setups and instruments via a geographic network and directly carry out real experiments. This laboratory has been devised on the basis of de-facto networking standards so that students are required to use only a simple commercial Internet Web browser. Moreover, a concurrence of more users on the same measuring setup is allowed. The remote laboratory concept allows measuring resources located at different geographically remote sites to be utilized by a wide distribution of students. In this way, a more complete educational proposal can be economically offered by several geographically remote laboratories specialized in different measuring fields.
In-Pixel Aperture CMOS Image Sensor for 2-D and 3-D Imaging (2018)

This paper presents a CMOS image sensor with the in-pixel aperture technique for single-chip 2-D and 3-D imaging. In conventional image sensors, the aperture is located at the camera lens. However, in the proposed image sensor, the aperture is integrated on the CMOS image sensor chip and is formed at a metal layer of the CMOS image sensor (CIS) process. A pixel array of the image sensor is composed of the W, R, B and PA pixels (W pixel with integrated metal aperture) for extracting color and depth information. While the image of the W pixel becomes blurred with increasing distance from a focused object, the image of the PA pixel maintains the sharpness. Therefore, the depth image can be obtained using the depth from the defocus method. The size of the pixel, which is based on a four-transistor active pixel sensor with pinned photodiode, is 2.8 μm × 2.8 μm. A prototype of the proposed image sensor was fabricated using the 0.11-μm CIS process and its performance was evaluated.
Mechanical Design and Development of Compact Linear Nanopositioning Flexure Stages with Centimeter-Level Travel Range and Nanometer-Level Resolution (2017)

Nanopositioning techniques present an important capability to support the state-of-the-art synchrotron radiation instrumentation research for the APS operations and upgrade project. To overcome the performance limitations of precision ball-bearing-based or roller-bearing-based linear stage systems, two compact linear nanopositiioning flexure stages have been designed and developed at the APS with centimeter-level travel range and nanometer-level resolution for x-ray experimental applications. The APS T8-54 linear flexure stage is designed to perform a precision wire scan as a differential aperture for the 3-D diffraction microscope at the APS sector 34, and the APS T8-56 linear flexure stage is designed for a horizontal sample scanning stage for a hard x-ray microscope at the APS sector 2. Both linear flexure stages are using a similar improved deformation compensated linear guiding mechanism which was developed initially at the APS for the T8-52 flexural linear stage *. The mechanical design and finite element analyses of the APS T8-54 and T8-56 flexural stages, as well as its initial mechanical test results with laser interferometer are described in this paper.
Poly(ethylene glycol)-lysine dendrimers for targeted delivery of nitric oxide (2006)

Abstract We have synthesized dendrimers of the amino-acid lysine bound to a central poly(ethylene glycol) (PEG) core, and then formed multiple diazeniumdiolate nitric oxide (NO) donors on the lysine residues. NO release from these materials occurred for up to 60 days under physiological conditions. These materials display the ability to regulate vascular cell proliferation and inhibit platelet adhesion to thrombogenic surfaces. When modified with a targeting ligand specific for inflamed endothelium (Sialyl Lewis X), we were able to demonstrate binding of fluorescently-labeled dendrimers to endothelial cells activated by interleukin 1β (IL-1β). Keywords: NITRIC OXIDEDENDRIMERTARGETED DRUG DELIVERYDIAZENIUMDIOLATESIALYL LEWIS X
Long-term blockade of vascular endothelial growth factor receptor-2 aggravates the diabetic renal dysfunction associated with inactivation of the Akt/eNOS-NO axis (2010)

Long-term selective blockade of VEGFR-2 by dRK6 had deleterious renal effects, and this was associated with downregulation of the Akt/eNOS-NO axis in db/db mice. Short-term VEGFR-2 blockade did not improve the renal phenotypes and the albuminuria. These findings suggest that VEGF-A-VEGFR-2 inhibition, regardless of how long it may be, does not ameliorate diabetic nephropathy in type 2 diabetes.
Phase Ib study of TSPP (thymidilate synthase poly-epitope peptide) vaccine in combination with GOLFIG chemoimmuno-burst in advanced colon cancer patients: Results from the TSPP/VAC-1/c trial. (2012)

e13098 Background: TSPP is a poly-epitope peptide anticancer vaccine able to generate a thymidylate syntase (TS) specific T cell response with antitumor activity in preclinical models, expecially when used in sequential combination with 5-FU. TS is in fact involved in DNA replication and is the major pharmacological target of fluoropyrimidines whose activity leads in turn to TS upregulation. On these basis we designed a phase Ib trial where we investigated the safety and the immunobiological activity of TSPP + GOLFIG (Gemcitabine + FOLFOX-4 + GM-CSF + IL-2) regimen. Methods: TSPP/VAC-1 (Eudract 2009-016897-33) is a monocentric dose finding Phase Ib trial. 12 pretreated metastatic colon cancer patients were enrolled between April and November 2011. All of them received biochemotherapy according to the GOLFIG regimen biweekly and TSPP (on day 7) diluted in motanide ISA720 (1:1) at the dosage of 100 (3 patients), 200 (3 patients) and 300 ug (6 patients). Results: No life-threatening adverse events were observed. Grade 3 leucopenia (2 cases), thrombocitopenia (3 cases), anemia (3 cases), nausea/vomiting (2 cases), and dyarrhea (4 cases) along with 3 cases of oxaliplatin reaction were recorded. Fever and flu-like symptoms were common along cytokine administration. An IFN-gamma ELISPOT assay recorded an increase in TS specific CTL precursors in 3/6 evaluable patients; it was also observed an increase in lymphocytes, eosinophils, terminal effector memory and central memory T cells and in both c-ANCA and p-ANCA (P= 0.02) in the peripheral blood and a significant reduction in inflammatory markers (LDH, CRP and ESR). Quality of life analysis revealed a general improvement in patients’health state along the treatment. 1 partial response, 6 disease stabilizations and 2 progessions of disease were recorded. TSPP Maximal Tolerated Dose was not reached, while the Optimal Biological Dose was identified at 300 ug. Conclusions: Our results suggest that the GOLFIG + TSPP vaccine combination is safe and immunologically active and deserves to be evaluated in a further phase II trial.
Computed Tomography of the Heart Using Thallium-201 in Children (1979)

Thallium-201 emission computed tomography (ECT) was performed in 3 pediatric patients in whom conventional scintigraphy was normal but there was a strong clinical suspicion of myocardial disease. Abnormalities in the distribution of myocardial perfusion appeared sharply. Single photon ECT provides a three dimensional reconstruction which results in greater enhancement since activity in overlying structures does not interfere. Its widespread use is limited only by the cost of the imaging device.
Immediate and Early Loading of Chemically Modified Implants in Posterior Jaws: 3‐Year Results from a Prospective Randomized Multicenter Study (2011)

Changes in crestal bone level occurred mostly during the first 5 months postloading. After this bone remodeling period, crestal bone level was stable up to 36 months. Implants with a chemically modified surface are safe and predictable for immediate and early loading in the posterior maxilla and mandible.
Extraglomerular origin of the mesangial cell after injury. A new role of the juxtaglomerular apparatus. (1997)

We investigated the origin of the glomerular mesangial cell, a smooth muscle-like cell that provides structural support in the glomerulus. Injection of anti-Thy 1 antibody that binds the Thy 1 antigen on rat mesangial cells eliminated (> 95%) the mesangial population at 20-28 h, while Thy 1-positive cells in the juxtaglomerular apparatus (JGA) were sequestered from the circulation and survived. Single pulse labeling with [3H]thymidine at 36 h labeled Thy 1-positive cells in the JGA and hilus. Serial biopsies demonstrated the progressive migration (5-15 micron/d) and proliferation of these mesangial reserve cells until the entire glomerulus was repopulated. The regenerating mesangial population expressed contractile and migratory proteins preferentially at the leading edge of the migratory front. Single as well as multiple pulse labeling with [3H]thymidine confirmed that the entire mesangial cell repopulation originated from only a few mesangial reserve cells. These reserve cells resided in the extraglomerular mesangium in the JGA and were not renin-secreting cells, macrophages, smooth muscle cells, or endothelial cells. These studies document mesangial cell migration in the anti-Thy 1 model of mesangial proliferative glomerulonephritis and provide evidence for a new role for the juxtaglomerular apparatus in the maintenance of the mesangial cell population.
Comparative Studies on Dehydrogenative Polymerization of Coniferyl Alcohol by Laccases and Peroxidases. Part 1. Preliminary Results (1996)

Article Comparative Studies on Dehydrogenative Polymerization of Coniferyl Alcohol by Laccases and Peroxidases. Part 1. Preliminary Results was published on January 1, 1996 in the journal Holzforschung (volume 50, issue 1).
Role of type A and Type B MAO in the metabolism of epinephrine in rat brain (1981)

Three different catecholamines appear to be neurotrans-mitters in brain: dopamine, norepinephrine and epinephrine. Dopamine and norepinephrine have been extensively studied as brain neurotransmitters during the past two decades. Less work has been done on brain epinephrine, which became a focus of attention only after Hokfelt et al (1974) showed that the epinephrine-forming enzyme, norepinephrine N-methyltransferase (EC 2.1.1.28), was present in rat brain in discrete tracts of neurons. These neurons presumably make and use epinephrine as their neurotransmitter and were suggested to have specific functions separate from those of dopamine and norepinephrine neurons (Hokfelt et al, 1974). Since then, various drug effects on brain epinephrine neurons have been described, including an increase in epinephrine concentration in rat brain following monoamine oxidase (MAO) inhibition (Fuller et al, 1979; Fuller et al, 1980; Scatton and Bartholini, 1980).
Stand-off hyperspectral imaging with a turn-key Mid-IR QCL dual-comb spectrometer for trace explosives detection (2021)

The identification of explosives residue and other harmful materials in field is a key problem to solve for world safety. Here we present a point-by-point imaging technique based on stand-off dual-comb spectroscopy carried out with QCL frequency combs using a fast scanning technique to provide hyperspectral images with species specific absorption spectra.
Survival of <i>Bifidobacterium animalis</i> DN-173 010 in the Faecal Microbiota after Administration in Lyophilised Form or in Fermented Product – A Randomised Study in Healthy Adults (2007)

The survival of Bifidobacterium animalis strain DN-173 010 was assessed after its ingestion in a fermented product or in a lyophilised form. Twelve healthy subjects were included in a randomised, open study with 2 parallel groups. The composition and activities of the faecal microbiota were monitored before (10-day baseline step), during (1-week product administration step) and after (10-day follow-up step) the ingestion of 1 of the 2 products. A colony immunoblotting method, fluorescent in situ hybridisation with group-specific DNA probes, and temporal temperature gradient gel electrophoresis using group-specific primers were carried out to compare survival of B. animalis strain DN-173 010 after ingestion of the 2 products, together with analyses of enzyme activities and faecal metabolites. At the end of the supplementation step, the mean number of B. animalis DN-173 010 quantified by immunodetection in the faeces of 5 of 6 subjects in each treatment group was >/=10(8) colony-forming units/g faeces. These numbers corresponded to an average survival of 22% for the lyophilised form and 20% for the fermented product. At the same step, the PCR temporal temperature gradient gel electrophoresis profiles showed a double band corresponding to the B. animalis DN-173 010 pattern for 11 subjects. No major modification was observed during the trial in either the dominant members of the faecal microbiota assessed by fluorescent in situ hybridisation or their activities. In conclusion, we show that the lyophilised form of B. animalis DN-173 010 survives transit and could represent a more convenient form to administer for long-term clinical trials.
Recombinant human BMP9 (RhBMP9) in comparison with rhBMP2 for ridge augmentation following tooth extraction: An experimental study in the Beagle dog (2018)

Within the limitations of the present study, rhBMP9 sites demonstrated higher bone-inducing potential in combination with DBBM than rhBMP2. While rhBMP9s failed to demonstrate a clear dose-response relationship to the outcomes, future studies are necessary to evaluate the appropriate dose and carrier systems.
Alveolar macrophage-derived chemotactic factor: kinetics of in vitro production and partial characterization. (1980)

Alveolar macrophages are the initial phagocytic cells that encounter foreign material and particulates deposited in the terminal airways. We have examined a mechanism by which these cells, after phagocytic challenge, may control or amplify the inflammatory response in lung parenchyma. Normal human alveolar macrophages (AM) were studied from eight subjects. With in vitro culture, AM produced and released two substances into culture media which have potent chemoattractant activity for blood polymorphonuclear granulocytes (PMN) and negligible activity for mononuclear cells. Release of these factors is maximally stimulated by aggregated human immunoglobulin (Ig)G or zymosan particles; however, simple adhesion of the macrophages to plastic surfaces is also sufficient to stimulate release of these chemotactic substances. The larger substance (10,000 daltons) is immunologically distinct from C5a and interacts with a different PMN membrane receptor than that known to exist for formyl-methionyl-leucyl-phenylalanine. Its chemotactic activity is sensitive to the enzymatic effect of trypsin. Although producing a single elution peak on gelfiltration chromatography, electrofocusing in polyacrylamide gels yielded five peaks of radioactivity. Chemotactic activity was localized to a fraction with a pI = 5.0. The smaller molecular weight substance has been less well characterized. Thus, the human AM can produce at least two factors which attract PMN and this capability may augment the local inflammatory response in the lung.
Fellow eye vitrectomy for proliferative diabetic retinopathy in an inner city population (2013)

Approximately a third of fellow eyes required diabetic vitrectomy within 3 years of primary eye vitrectomy. Primary eye surgical indication and younger age were significant predictors of need for fellow eye surgery.
Novel RNA-binding activity of MYF5 enhancesCcnd1/Cyclin D1mRNA translation during myogenesis (2016)

Skeletal muscle contains long multinucleated and contractile structures known as muscle fibers, which arise from the fusion of myoblasts into multinucleated myotubes during myogenesis. The myogenic regulatory factor (MRF) MYF5 is the earliest to be expressed during myogenesis and functions as a transcription factor in muscle progenitor cells (satellite cells) and myocytes. In mouse C2C12 myocytes, MYF5 is implicated in the initial steps of myoblast differentiation into myotubes. Here, using ribonucleoprotein immunoprecipitation (RIP) analysis, we discovered a novel function for MYF5 as an RNA-binding protein which associated with a subset of myoblast mRNAs. One prominent MYF5 target was Ccnd1 mRNA, which encodes the key cell cycle regulator CCND1 (Cyclin D1). Biotin-RNA pulldown, UV-crosslinking and gel shift experiments indicated that MYF5 was capable of binding the 3' untranslated region (UTR) and the coding region (CR) of Ccnd1 mRNA. Silencing MYF5 expression in proliferating myoblasts revealed that MYF5 promoted CCND1 translation and modestly increased transcription of Ccnd1 mRNA. Accordingly, overexpressing MYF5 in C2C12 cells upregulated CCND1 expression while silencing MYF5 reduced myoblast proliferation as well as differentiation of myoblasts into myotubes. Moreover, MYF5 silencing reduced myogenesis, while ectopically restoring CCND1 abundance partially rescued the decrease in myogenesis seen after MYF5 silencing. We propose that MYF5 enhances early myogenesis in part by coordinately elevating Ccnd1 transcription and Ccnd1 mRNA translation.
A framework for MT and multilingual NLG systems based on uniform lexico-structural processing (2000)

In this paper we describe an implemented framework for developing monolingual or multilingual natural language generation (NLG) applications and machine translation (MT) applications. The framework demonstrates a uniform approach to generation and transfer based on declarative lexico-structural transformations of dependency structures of syntactic or conceptual levels ("uniform lexico-structural processing"). We describe how this framework has been used in practical NLG and MT applications, and report the lessons learned.
Controlled Assembly of Micrometer-Sized Spheres:  Theory and Application (2007)

Site-selective assembly of 5 microm amine-functionalized glass spheres from aqueous suspensions onto gold surfaces patterned with carboxylic acid and methyl-terminated thiols has been achieved through the introduction of a variable tilt flow cell. In situ microscope imaging has been employed to study the four phases of assembly independently, and the relative roles of electrostatic attraction and capillary emersion have been explored. In contradiction to the commonly recognized electrostatic assembly model, detailed theoretical analysis and experimental evidence are presented to support a mechanism where patterning occurs at the point of meniscus contact. Control of pattern quality is demonstrated through the comparison of results obtained from a variety of experiments, and the best conditions for the assembly of monolayer features are identified. Finally, evidence for the extension of this assembly method to the production of singlet sphere arrays is discussed.
TMOD-03. GLIOMAPDOX: A MOLECULARLY DIVERSE LIBRARY OF DIRECT-FROM-PATIENT ORTHOTOPIC GLIOMA XENOGRAFTS RECAPITULATES INTRATUMOR HETEROGENEITY (2018)

8mg/day for 5 days, whereupon mice were sacrificed and eyes removed and fixed in 4% PFA. Retinas were then extirpated, stained with Fn antibody and DAPI, mounted, and imaged by scanning laser confocal microscopy. z-stacks were collected and penetration distance assessed. 3-color images were generated for localization of pGBM cells, FNMA and DAPI. Additionally experiments were performed in the presence of Dex and either FUD fragment, an inhibitor of FNMA, or iii-11C control peptide. RESULTS: We show that Dex significantly reduces z-axis penetration of pGBM cells into mouse retina, that Dex treatment significantly alters the morphology of dispersal of injected pGBM cells within the x,y plane, that without Dex, the presence of fibronectin increases dispersal, that Dex treatment activates FNMA by pGBM cells leading to containment of the tumor mass, and that Dex-mediated activation of FNMA is fibronectin dose-dependent. Moreover, treatment with FUD but not iii-11C restores ability of tumor cells to disperse. Interestingly, dispersal inhibition could be achieved at Dex doses as low as 1mg/day. CONCLU-SION: Our study defines a role for fibronectin as a facilitator of pGBM dispersal and Dex-mediated activation of FNMA as an inhibitor of that process.
AlGaN/GaN Heterostructure Field-Effect Transistors on 4H-SiC Substrates with Current-Gain Cutoff Frequency of 190 GHz (2008)

We report on state-of-the-art AlGaN/GaN heterostructure field-effect transistor (HFET) technology in the scope of millimeter-wave applications. 60-nm-long-gate HFETs having 4- and 6-nm-thick Al0.4Ga0.6N barrier layers and SiN passivation layers formed by catalytic chemical vapor deposition (Cat-CVD) were fabricated on 4H-SiC substrates. Both structures had low sheet resistances of 200–220 Ω/sq that were due to not only high mobilities of 1900–2000 cm2/(V·s) but also high electron densities of (1.4-1.7)×1013 cm-2, which were provided by the high-Al-composition barrier layers and the Cat-CVD SiN. The devices with the 4- and 6-nm-thick barriers had maximum drain current densities of 1.4 and 1.6 A/mm and peak extrinsic transconductances of 448 and 424 mS/mm, respectively. Maximum fT and fmax reached 190 and 251 GHz, respectively.
Attenuation of Microwave Acoustic Surface Waves Due to Gas Loading (1972)

Experimental measurements of microwave acoustic surface-wave attenuation due to propagation at the boundary of a solid and a monatomic gas are presented. Data illustrate attenuation as a function of frequency, molecular weight, pressure, and temperature. Experimental results are compared to both an approximate and a continuum mechanical theory. For the frequencies of interest (500–2500 MHz) the approximate theory gives better agreement with experiment. A summary of data of attenuation due to air loading at 1 GHz is presented for a number of low-loss acoustic surface-wave substrates. Of practical interest is the fact that microwave acoustic surface-wave delay lines and other signal-processing devices must be encapsulated in either helium or vacuum if minimum insertion loss is desired.
The process of homelessness: an event history analysis of length of stay for the Groningen shelter accommodation (2010)

This study explores the process of shelter exits for homeless individuals and for different shelter types in the public shelter system in the city of Groningen in the Netherlands. Individualised administrative data from the Groningen Homelessness Monitor (2003–2006) are used for estimating a Weibull hazard rate regression model. Results show that the different shelter types fit adequately with their policy purposes : lengths of stay in emergency shelter accommodation appear to be shorter than in supportive housing accommodation and clients tend to remain longest in guest houses. The results also indicate that the use of day shelters, as well as demographic variables such as age, gender and nationality, are associated with a differentiated likelihood of continuing homelessness. The results of this study in the Dutch context are compared with research on the process of homelessness in the United States, and finally the implications of these findings and future directions for research on the process of homelessness are discussed.