gebhart/patrepeval huggingface dataset:
Dynamic Imaging of Current Conduction in Dielectric Films by Emission Microscopy (1987)

Real time images of the dielectric breakdown were shown in a movie produced by Emission Microscopy. We show that a faint light is emitted during current conduction through dielectric films. Current flows through a large area in an undamaged oxide. Upon breakdown the current flow immediately constricts into a tiny point. Current flow at asperities dances around between multiple asperities. This behavior can be understood as a result of electron trapping and detrapping in the vicinity of poly asperities. Emission Microscopy is the only known technique for viewing current localization at asperities. It is also the most sensitive and the fastest technique for locating oxide defects in VLSI products.
Study on 3D-MEMS Optical Switch Module (2014)

MEMS 23D MEMS 2.1 2 3D MEMS MEMS
Vascular Endothelial Growth Factor -- Its Role in Retinal Vascular Proliferation (1994)

The blood vessels of the human retina do not normally grow after birth. All postnatal neovascularization in this tissue is therefore pathologic, arising as a complication of diseases such as diabetes, sickle cell disease, and retinal-vein occlusion. The new vessels lack the barrier function of the normal retinal circulation and permit extravascular leakage of blood components. Because of their extremely thin endothelium, these vessels are fragile and can easily rupture, causing hemorrhage into the vitreous cavity. New retinal vessels are surrounded by fibroblasts or glial cells that may proliferate extensively as the disease progresses. The tough, contractile bands and membranes . . .
Evaluation of Anticonvulsant Action of Nebivolol in Albino Mice (2023)

Background: Epilepsy is a disorder of brain function indicating periodic and unpredictable occurrence of seizures. Hypertension is the main cause of intracerebral hemorrhage which is a triggering factor for development of epilepsy. Nebivolol, a β-blocker is an anti-hypertensive drug, could decrease the glutaminergic transmission with addition of antioxidant property as a contributing factor may possibly provide anticonvulsant effect. Aim and Objective: The aim of the study was to study the anticonvulsant effect of Nebivolol in Albino mice. Materials and Methods: An either sex of Albino mice weighing between 18 and 22 g were used. Forty-eight animals (n = 48) were divided into eight groups with six in each group; four groups each for maximal electroshock (MES) and pentylenetetrazole (PTZ) models, respectively. Hind Limb Flexion, Hind Limb Extension, Clonus, and Postictal Depression were observed using MES model, Seizure latency and Duration of seizures were observed using PTZ model. Results: Nebivolol showed anticonvulsant effect with MES convulsions at both 0.25 mg/kg and 0.5 mg/kg but this effect is not equivalent to that of phenytoin in the present study. In terms of duration of tonic hind limb flexion and post-ictal depression, Nebivolol 0.5 mg/kg dose has comparable results to that of phenytoin. In PTZ model, Nebivolol decreased the seizure duration but did not delay the seizure onset, which were comparable to the standard Diazepam. Conclusion: Nebivolol may possibly be beneficial in treating generalized tonic clonic seizures and absence seizures. However, more extended studies are needed to prove the anticonvulsant effect of Nebivolol and enable its use in clinical practice.
Data for: Green and facile preparation of hydrophobic bioplastics from tea waste (2021)

Data for: Green and facile preparation of hydrophobic bioplastics from tea waste
The actin-based motility of intracellularListeria monocytogenesis not controlled by small GTP-binding proteins of the Rho- and Ras-subfamilies (1999)

In this study, we analyzed whether the actin-based motility of intracellular Listeria monocytogenes is controlled by the small GTP-binding proteins of the Rho- and Ras-subfamilies. These signalling proteins are key regulatory elements in the control of actin dynamics and their activity is essential for the maintenance of most cellular microfilament structures. We used the Clostridium difficile toxins TcdB-10463 and TcdB-1470 to specifically inactivate these GTP-binding proteins. Treatment of eukaryotic cells with either of these toxins led to a dramatic breakdown of the normal actin cytoskeleton, but did not abrogate the invasion of epithelial cells by L. monocytogenes and had no effect on the actin-based motility of this bacterial parasite. Our data indicate that intracellular Listeria reorganize the actin cytoskeleton in a way that circumvents the control mechanisms mediated by the members of the Rho- and Ras-subfamilies that can be inactivated by the TcdB-10463 and TcdB-1470 toxins.
Pointer Analysis (Dagstuhl Seminar 13162) (2013)

This report documents the program and the outcomes of Dagstuhl Seminar 13162 ``Pointer Analysis''. The seminar had 27 attendees, including both pointer analysis experts and researchers developing clients in need of better pointer analysis. The seminar came at a key point in time, with pointer analysis techniques acquiring sophistication but still being just beyond the edge of wide practical deployment. The seminar participants presented recent research results, and identified key open problems and future directions for the field. This report presents abstracts of the participants' talks and summaries of the breakout sessions from the seminar.
Highly concurrent shared storage (2002)

Switched system-area networks enable thousands of storage devices to be shared and directly accessed by end hosts, promising databases and file systems highly scalable, reliable storage. In such systems, hosts perform access tasks (read and write) and management tasks (storage migration and reconstruction of data on failed devices.) Each task translates into multiple phases of low-level device I/Os, so that concurrent host tasks accessing shared devices can corrupt redundancy codes and cause hosts to read inconsistent data. Concurrent control protocols that scale to large system sizes are required in order to coordinate on-line storage management and access tasks. In this paper we identify, the tasks that storage controllers must perform, and propose an approach which allows these tasks to be composed from basic operations-called base storage transactions (BSTs)-such that correctness requires only the serializability of the BSTs and not of the parent tasks. We present highly scalable distributed protocols which exploit storage technology trends and BST properties to achieve serializability while coming within a few percent of ideal performance.
Field Tests of Industrial Boilers Cofiring Hazardous Wastes (1984)

Thirteen field emission tests have been performed on eight industrial boilers cofired with conventional fuels and hazardous wastes. The U.S. Environmental Protection Agency (EPA) sponsored the tests to evaluate the effectiveness of industrial boilers for hazardous waste thermal destruction while recovering useful energy. Five initial tests were made on a wide range of waste type/boiler design combinations to quantify emissions representative of current industry practices. For the second series of tests, boilers firing waste streams spiked with a mixture of carbon tetrachloride, chlorobenzene, and trichlorethylene were tested to extend the data base for chlorinated wastes and facilitate intrasource comparisons. Principal organic hazardous constituents (POHC's) in the flue gas were quantified using two extractive sampling trains. Volatile compounds were absorbed on two Tenax traps in the volatile organic sampling train (VOST). Semivolatile compounds were absorbed on XAD-2 sorbent in a modified Method 5 train. The sampling protocol also included continuous monitor measurement of stack O2, CO, CO2, NOX and total hydrocarbons; extractive train samples of HC1; and grab samples of the conventional and waste fuels and ash streams. Post-test analyses of the inlet fuels and the outlet stream samples were done with gas chromatography/mass spectrometry to quantify the destruction and removal efficiency of POHC's. Results for the thirteen tests are discussed in this paper. Specie destruction and removal efficiency (DRE) ranged from 99.5 to >99.999 percent. The mass weighted destruction efficiency for all RCRA Appendix VIII compounds was 99.998 percent. Products of incomplete combustion (PIC's) were observed in concentrations one order of magnitude greater than measured POHC breakthrough.
Vergence Dynamics Predict Fixation Disparity (2001)

The neural origin of the steady-state vergence eye movement error, called binocular fixation disparity, is not well understood. Further, there has been no study that quantitatively relates the dynamics of the vergence system to its steady-state behavior, a critical test for the understanding of any oculomotor system. We investigate whether fixation disparity can be related to the dynamics of opponent convergence and divergence neural pathways. Using binocular eye movement recordings, we first show that opponent vergence pathways exhibit asymmetric angle-dependent gains. We then present a neural model that combines physiological properties of disparity-tuned cells and vergence premotor cells with the asymmetric gain properties of the opponent pathways. Quantitative comparison of the model predictions with our experimental data suggests that fixation disparity can arise when asymmetric opponent vergence pathways are driven by a distributed disparity code.
Structural Transitions of the Metal-Oxide Nodes within Metal–Organic Frameworks: On the Local Structures of NU-1000 and UiO-66 (2016)

In situ pair distribution function (PDF) analyses and density functional theory (DFT) computations are used to probe local structural transitions of M6O8 nodes found in two metal organic frameworks (MOFs), NU-1000 and UiO-66, for M = Zr, Hf. Such transitions are found to occur without change to the global framework symmetry at temperatures within a range relevant to many potential MOF applications. For the particular M6(O)8 nodes studied here, the observed distortions can be mapped to polymorphic forms known for bulk ZrO2. In the MOF framework, however, node distortions are found to occur at substantially lower temperature than analogous distortions in bulk ZrO2 owing to the nanoscale nature of the former.
Electro fluido dynamic techniques to design instructive biomaterials for tissue engineering and drug delivery (2015)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Vincenzo Guarino, Rosaria Altobelli, Valentina Cirillo, Luigi Ambrosio; Electro fluido dynamic techniques to design instructive biomaterials for tissue engineering and drug delivery. AIP Conf. Proc. 17 December 2015; 1695 (1): 020004. https://doi.org/10.1063/1.4937282 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
CAN YOU STILL HEAR ME IN THE BACK OF THE ROOM? (2000)

This forum article is the first in a series on lessons learned and best practices in civil engineering education. The intent of the series is to reinforce good practices, describe new developing practices, and provide a forum for what works well and what does not. This article focuses on the principle of active learning. A good teacher cannot motivate simply by being a subject matter expert and guiding the direction of the learner. A good teacher must also teach, breaking down the material into easily understood pieces and presenting how the material is used, why it is important, and where to go from there. A very small percentage of college undergraduates are highly motivated active learners. The vast majority require at least some direction, an occasional or frequent push, and lost of encouragement. In an active learning environment, students are engaged in the material, actively listening, notetaking, and questioning the teacher and students beside them. There is an energy or slight tension in the room, conveying the material is tough, exciting, and important. Although there may be a great deal of time spent on presentation, the instructor interacts with the students. There is great rapport between the instructor and the students, but it is related to the material at hand and not frivolous. The instructor attempts to make abstractions concrete through illustrations or examples and to keep students involved through a variety of techniques. The best way for instructors to keep students from being bored by a subject is to show them that they are not bored by it. Material should be carefully prepared, but the method of delivery should appear spontaneous, as if the teacher were having the thoughts and presenting that material for the first time.
WE‐G‐211‐03: Development of Ultrasound Imaging Equipment (2012)

1. Describe features of the first commercially available ultrasound scanners. 2. Identify the relationship between technological developments in radar and emergence of ultrasound as a modality 3. Explain the significance of a high large channel count in beamforming 4. Contrast echo acquisition and processing in a modern scanner with first generation devices.
[Basic diagnostics of sleep disorders: possibilities of the family physician]. (2007)

Many sleep disorders can be definitively diagnosed using basic diagnostics in the family practice. Important elements of the diagnosis are the patient's general medical history and acquiring a description of the current phenomenology of the disorder. The use of sleep diaries and information provided by a third party are also helpful. For chronic sleep disorders, patient habits that are not in line with the rules of good sleep hygiene should be regarded as potential perpetuating causes of the disorder. In some cases, simple test procedures can also be useful. The identification or the exclusion of a primary physical or mental disease whose symptom may be the sleep disorder (example: insomnia for underlying depression) is important. In some cases, referral to a specialist or to a sleep medicine centre is necessary.
Prototype of Multiplex Bead Assay for Quantification of Three Serum Biomarkers for In Vitro Diagnosis of Endometriosis (2016)

Endometriosis is a very common disease, affecting 10% of women in the reproductive age. To date, a significant delay between onset of the symptoms and definitive diagnosis is caused by the lack of a reliable non-invasive diagnostic test. Recently, the potential value as diagnostic markers for endometriosis of three proteins (Zn-alpha2-glycoprotein, serum albumin, and complement C3 precursor), has been showed. In this article, we have defined the experimental conditions for the development of a multiplex bead array assay for rapid and simultaneous quantification of these three biomarkers in the serum of patients with endometriosis. Finally, pivotal experiments on a small cohort of patients have confirmed the diagnostic value of this assay. J. Cell. Physiol. 231: 2622-2627, 2016. © 2016 Wiley Periodicals, Inc.
Light Material Interactions in Energy Conversion (Final Report) (2019)

The scientific vision of the “Light-Material Interactions in Energy Conversion” Energy Frontier Research Center (LMI-EFRC) is embodied in our mission statement: ‘to tailor the morphology, complex dielectric structure, and electronic properties of matter so as to sculpt the flow of sunlight and heat, enabling light conversion to electrical energy with unprecedented efficiency’. Founded in 2009, the LMI-EFRC has become a national resource for fundamental optical principles and phenomena relevant to solar energy conversion, addressing new scientific opportunities that enable efficient utilization of the entire visible and infrared solar resource. The LMI-EFRC is directed by Prof. Ralph Nuzzo and centered at its lead institution, the California Institute of Technology. The Center is an integrated and collaborative partnership of research leaders in photonics and photonic materials, comprising 14 faculty investigators that span six academic departments at five institutions, including Profs. Harry Atwater, Andrei Faraon, Nathan Lewis, and Austin Minnich at Caltech; Profs. Ralph Nuzzo, Paul Braun and John Rogers at the University of Illinois at Urbana-Champaign; Prof. Jennifer Lewis at Harvard University; Profs. Mark Brongersma, Jennifer Dionne, and Shanhui Fan at Stanford University; and Profs. Paul Alivisatos, Eli Yablonovitch, and Xiang Zhang at Lawrence Berkeley National Laboratory. The Center is organized into four research groups (RGs) that address scientific themes related to light-matter interactions, with each team spanning multiple institutional partners and designed to meet our scientific objectives. Notable project outcomes that address the LMI Mission and 2014-2018 goals include: RG1 “New Light Management Mechanisms” demonstrated tunable and active nanostructured patterned surfaces (‘metasurfaces’) for control of light absorption, reflection, and propagation. RG2 “Solar Spectrum Control and Conversion” developed colloidal nanocrystals with designer optical properties for fundamental studies of solar spectrum control and conversion. RG3 “Thermal Photon Harvesting” established photonic design principles to harness and control thermal photons in novel conversion systems. RG4 “Programmable Assembly of Photonic and Electronic Architectures” developed powerful new methods for light- and matter-based additive fabrication of electronic and photonic architectures.
Process, space and software development support (1995)

Over the past five years we have been actively investigating support frameworks for collaborative software development. Our goal has been the development of an open framework for support of collaborative work activities which provides active guidance and help to the user and allows for dynamic modification of collaboration protocols as work situations evolve. In this position paper we outline our current thinking on support frameworks for the collaborative efforts of teams of software developers. We postulate that a space-based metaphor for collaborative systems opens the door to the design and construction of families of next-generation software process environments which are open in that many different kinds of processes can be specified significantly more flexible than existing systems in their affordances for evolution of process models, and provide integrated support for both formal and informal collaborative activities of their users.
Hydrophobic hydration affects growth of clathrate hydrate: insight from an NMR relaxometric and calorimetric study (2019)

Water tightly bound to the kinetic inhibitors of tetrahydrofuran hydrate and natural gas hydrate has a relaxation time scale of sub-milliseconds. The amounts of such water are related to the inhibition time before rapid growth of the hydrate crystals and the hydrophobic hydration effect of the inhibitors.
Sensory Nerve Conduction and Somatosensory Evoked Potentials of the Trigeminal Nerve in Horses with Idiopathic Headshaking (2013)

This study confirms involvement of the trigeminal nerve hyperexcitability in the pathophysiology of disease. Further, results might support a functional rather than a structural alteration in the sensory pathway of the trigeminal complex that can be seasonal. The horse could serve as a natural animal model for humans with idiopathic trigeminal neuralgia.
M apping of protein:protein contact surfaces by hydrogen / deuterium exchange, followed by on-line high-performance liquid chromatography-electrospray ionization fourier-transform (2002)

For protein complexes too large, uncrystallizable / insoluble, or low concentration for conventional X-ray diffraction or 2 nuclear magnetic resonance analysis, the contact surface(s) may be mapped by comparing H / H exchange rate (and thus 2 solvent accessibility) of backbone amide hydrogens in free vs. complexed protein(s). The protein is first exposed to H O, 2 allowed to exchange for each of several reaction periods, and then digested with pepsin. The extent and rate of H / H 2 exchange is determined by measuring the increase in mass with H / H exchange period for each of the peptides. Here, we present an experimental protocol that combines rapid (to minimize back-exchange) HPLC front-end separation with ultrahigh-resolution mass analysis (needed to distinguish the isotopic distributions of dozens of peptides simultaneously). The method is used to study the assembled human immunodeficiency virus type capsid protein (CA) and its soluble form.  2002 Elsevier Science B.V. All rights reserved.
Characteristics of the Chemotactic Activity of Heparin Cofactor II Proteolysis Products (1990)

The physiological function of the serpin (serine proteinase inhibitor) heparin cofactor II (HCII) is not well understood. A role for HCII as an inhibitor of thrombin in the presence of dermatan sulfate and heparin has been proposed. Neutrophils (PMN) are the major cellular component of acute inflammation. HCII can be proteolytically inactivated by cathepsin G (CG) and elastase (LE), which are released by stimulated PMN. We have recently shown that reaction products of HCII with CG and LE are potent chemotaxins for PMN. Monocytes (monos) appear later in the course of inflammation than do PMN. They differentiate into macrophages in the tissues and participate in healing of damaged tissue and initiating immune responses. We found that the proteolysis products of HCII were chemotactic for monocytes in a fashion similar to their effects on PMN. At 10(-8) to 10(-9) M, the chemotactic activity of HCII proteolysis products was comparable to that of 10(-8) M N-formyl-Met-Leu-Phe (fMLP). The chemotactic activity of HCII-proteinase reaction products is mediated by a different mechanism than that of alpha 1 proteinase inhibitor (alpha 1 PI)-LE complexes or fMLP. Our data suggest that chemotactic activity generated by proteolysis of HCII is not due to the conformational change induced by cleavage of the exposed loop near the reactive site nor by release of the reactive site peptide. We also compared the effects of HCII reaction products and fMLP on expression of Mac-1 and p150,95 adhesive proteins. Mac-1 has been implicated in mono adhesion and chemotaxis and as a potential initiator of coagulation. The surface expression of Mac-1 was not increased above control levels by incubation of leukocytes with HCII digests, even though fMLP did increase surface Mac-1. Proteolysis products of HCII could play a role in the initial influx of PMN into a thrombus, and in the transition from acute to chronic inflammation, or to granulation and healing.