gebhart/patrepeval huggingface dataset:
Transport properties of branched graphene nanoribbons (2008)

The electronic transport properties of three-terminal graphene nanoribbon T-junctions are investigated using a quantum tight binding molecular dynamics scheme. The transport properties are found to depend very sensitively on the geometric features of the branches of the junctions. This dependence is even more pronounced than the corresponding dependence in the case of T-shaped single wall carbon nanotubes. This is attributed to the strong dependence of the conductivity of the nanoribbons on their chirality, width, and length. An additional factor that influences the conductivity of the T-junction nanoribbons is associated with the junction itself, i.e., the way the branches are interconnected.
Data-driven Approach on Human-like Walking and Running Based on Passive Dynamical Mechanism (2018)

In this research, we are going to verify how deep reinforcement learning and anomaly detection etc, which are drawing attention in the field of artificial intelligence, can be utilized. In particular, we accumulate know-how in application to real walking and running machines. In this paper, we report some results of preliminary experiments.
La place des transmissions orales dans la continuité des soins (2017)

Au cours des differents stages que j’ai ete amene a realiser au cours de ma formation, j’ai pu assister et participer a un moment important de l’organisation du travail entre deux equipes soignantes : le temps des transmissions orales. J’ai ete surpris par la quantite d’informations concernant les patients qui etaient echangees durant ce moment, et a quel point cette pratique avait un impact important sur la continuite des soins. Je me suis rendu compte que si les transmissions orales avaient pour but d’aider l’infirmiere dans l’organisation de son travail, elles pouvaient parfois etre source d’erreur. Je me suis demande quels moyens utilisaient les infirmieres pour realiser des transmissions orales de qualite permettant une prise en charge efficace des patients. J’ai ainsi cherche a savoir si les infirmieres utilisaient une methodologie pour organiser les informations qu’elles donnaient a l’oral. La methodologie de classement dite MTVED (Maladie, Therapeutiques, Vecu, Environnement et Developpement) est utilisee pour la redaction ecrite des macrocibles de syntheses de prise en charge des patients. J’ai emis l’hypothese que l’utilisation de cette methodologie comme un support de classement des informations permettait aux infirmieres de realiser des transmissions orales de qualite. J’ai decide de realiser une etude de type qualitative, en realisant des entretiens avec des infirmieres d’une unite de soins afin de connaitre leur point de vue sur les transmissions orales et confronter mon hypothese a la realite travail. J’ai realise ces entretiens aupres de cinq infirmieres dans un service de medecine. J’ai ensuite effectue un travail de retranscription et d’analyse de ces donnees. Je me suis rendu compte que si toutes les infirmieres interrogees connaissaient la methodologie MTVED une seule disait la trouver pertinente en tant que support pour les transmissions orales. Mais en analysant plus profondement les propos, j’ai pu mettre en lumiere le fait qu’elles s’appuient toutes en partie sur cette methodologie sans s’en rendre compte. Je ne peux donc pas completement affirmer mon hypothese. Pour cela il me faudrait realiser une etude plus large et eventuellement creer un outil de support pour les transmissions orales base sur cette macrocible afin de le teste r dans un service de soins
Research on optimal Traditional Chinese Medicine treatment of knee ostarthritis with data mining algorithms (2012)

At present, more and more patients suffering from knee OA (Ostarthritis) are treated with complementary and alternative medicine, such as herbal drugs, herbal patches, acupuncture and manipulation etc, as an effective therapy. However, traditional statistical methods data gathered from randomized controlled trials (RCT) which were considered as the golden standard for therapy effectiveness failed to confirm those therapies efficacy. Whether we can accurately predict these therapeutic effects on the basis of a prospective, five-center, parallel-group, randomized controlled trial by means of other innovative ways is the question. According to this question, our team adopted several commonly used data mining algorithms to study it, such as KNN (k-Nearest Neighbor algorithm), j48 (decision tree), ANN (Artificial Neural Network). By means of modeling analysis of the patients' Traditional Chinese Medicine (TCM) symptoms questionnaire, Western Ontario and McMaster Universities Index of OA (WOMAC) total score and SF-36 assessment to predict the therapeutic effect which a patient can achieve after adopting one of those TCM therapies. Then we comprehensively analysed the effect and characteristic of every therapy schedule.
An expert system for process monitoring, diagnostics and control (VLSI and ULSI circuits) (2002)

An expert system for monitoring VLSI and ULSI integrated circuit process parameters which is based on the concepts of the charge-capacitance method is described. The process parameters determined are oxide leakage current, impedance to establish electric contact quality, oxide layer thickness, semiconductor doping profile, oxide fixed charge density, interface trap density, semiconductor band bending, and threshold voltage of a MOSFET. Instrumentation and measurement are discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Hepatitis B vaccination of newborn infants in rural China: evaluation of a village-based, out-of-cold-chain delivery strategy (2007)

Timely administration of the first dose of HepB vaccine was improved by communication and training activities, and by out-of-cold-chain storage of vaccine and administration at the village level, especially among children born at home.
Compensation for EUV multilayer defects within arbitrary layouts by absorber pattern modification (2011)

According to the ITRS roadmap, mask defects are among the top technical challenges to introduction of extreme ultraviolet (EUV) lithography into production. Making a multilayer defect-free extreme ultraviolet (EUV) blank is not possible today, and is unlikely to happen in the next few years. This means that EUV must work with multilayer defects present on the mask. The method proposed by Luminescent is to compensate effects of multilayer defects on images by modifying the absorber patterns. The effect of a multilayer defect is to distort the images of adjacent absorber patterns. Although the defect cannot be repaired, the images may be restored to their desired targets by changing the absorber patterns. This method was introduced in our paper at BACUS 2010, which described a simple pixel-based compensation algorithm using a fast multilayer model. The fast model made it possible to complete the compensation calculations in seconds, instead of days or weeks required for rigorous Finite Domain Time Difference (FDTD) simulations. In this paper the method is extended from one-dimensional to two-dimensional patterns by formulating the problem with level-set methods. Since only the top layer profile is measurable a multi-layer growth model is applied to infer the location of the defect and how it distorts the multi-layer reflector. The fast image model is applied to determine how these assumptions influence accuracy of the compensation method.
Next-generation sequencing of formalin-fixed, paraffin-embedded tumor biopsies: navigating the perils of old and new technology to advance cancer diagnosis (2013)

Formalin-fixed, paraffin-embedded (FFPE) tumor biopsies are a primary pathological specimen for oncology diagnostics. Hundreds of millions of such biopsies exist, and the method for creating them p...
Envelope Fluctuation Statistics of Filtered PSK and Other Digital Modulations (1979)

Radio signals derived using constant-envelope digital modulations (e.g., PSK, FSK and variations thereon) are impervious to the nonlinear characteristics of high-power RF amplifiers such as TWT's. However, constant-envelope modulations that must be heavily filtered to meet spectrum emission requirements, or intrinsically spectrumefficient modulations such as Quadrature Partial Response Signaling (QPRS), exhibit envelope fluctuations that render them vulnerable to amplifier nonlinearities. This paper describes a study, based on the use of Monte Carlo computer simulations, of the RF envelope variations associated with different digital modulations. Simulations and statistical analyses of these variations have been conducted for both filtered PSK and QPRS. The PSK category includes such special cases as Staggered Quaternary PSK (SQPSK); Minimum Shift Keying (MSK); <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">L</tex> -ary PSK with cosine rolloff shaping (divided equally between transmitter and receiver); and linear phase modulation using shaped (nonrectangular) baseband pulses. The primary fluctuation measure used in the study is the dynamic range, in decibels, between the 10th and 90th percentiles of the RF envelope. This quantity, <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">D</tex> , is presented for the various modulations considered and for various types of transmit filtering, with filter bandwidth-to-symbol rate ratio treated as a variable. The numerical results show the tradeoff between envelope constancy and spectrum efficiency among the most widely used digital radio approaches. For QPRS modulations, <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">D</tex> is typically in the range 11-16 dB; for heavily filtered PSK modulations, the range of <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">D</tex> lies roughly 6 dB lower, but other sources of distortion are more prominent.
Experimental Study on the Cutting Performance of TiC-Based Nanocomposite Ceramic Tools in Turning 40Cr Steel (2011)

TiC-based ceramic cutting tools with three different particle size levels of Al 2 O 3 additives were fabricated and tested. Theses tool materials were identified as TA, TA10A5 and TA30A5 respectively in this study. Another commercial cutting material identified as LT55 was used in this study as baseline to investigate cutting performance by comparing the flank wear size. The experimental results showed that multi-scale nanocomposite ceramic tool TA10A5 had much better wear resistance than the other tools when turning at a lower speed. The wear mechanisms were mainly adhesive wear in the rake face. While cutting at a higher speed, the breakage failure occurred for the tools TA10A5 and TA30A5.
Acquisition of historical knowledge from encyclopedic texts (1997)

Automatic acquisition of historical knowledge from encyclopedic texts involves addressing three issues in the field of artificial intelligence: natural language understanding, knowledge representation, and knowledge acquisition. Semantic interpretation, a component of natural language understanding, is responsible for the construction of logical forms from syntactic relations produced by the parser. Nominalized verbs, or nominalizations, contribute the same knowledge as their verbal counterparts, and behave like their verbal forms in that they license prepositional phrases. The nominalizations found in these texts are often ambiguous. Unlike previous treatments of nominalizations which skirted the ambiguity issue, the problems of choosing between the verbal and non-verbal senses of nominalizations and handling the polysemy of the nominalized verb were addressed head on.
Another key principle for semantic interpretation is the the creation of verbal knowledge, in the form of verb meaning (VM) rules and verbal concepts. Both of these constructs require a hierarchy of concepts to specify selectional restrictions. Over 220 new VM rules and 140 new verbal concepts were written, covering a wide range of relations. Testing of the system with this verbal knowledge and its supporting ontology showed that the correct sense of the verb and the correct attachment and meaning for prepositional phrases were determined more than 90% of the time.
An investigation into how to recognize semantic connections between sentences and how to use those connections to acquire implicit knowledge was performed. Temporal connections are particularly important because they provide a foundation for acquiring other, more challenging relations such as causal connections. Representations of temporal and causal relations are presented along with methods for automatically acquiring them.
These algorithms were tested on articles of the electronic version of the World Book Encyclopedia. An application was created which accepts questions about historical figures and using knowledge acquired from encyclopedic articles, answers them. This application, called SNOWY-BIOS, was tested on ninety-one different English questions. The answers produced by the system were compared against answers produced by two human subjects using the same version of the encyclopedia. Recall and precision scores of 54% and 85% respectively were found when compared against the humans' performance.
The Expression of the Kallikrein Gene Family in the Rat Pituitary: Oestrogen Effects and the Expression of an Additional Family Member in the Neurointermediate Lobe (1989)

Abstract Using a series of oligonucleotide probes (18 to 21 mers) specific for members of the rat kallikrein/tonin gene family (PS, S1, S2, S3, K1, P1), we have shown by Northern blot analysis that the oestrogen-dependent kallikrein gene expressed in the male and female rat anterior pituitary is true kallikrein (PS). In addition, we have demonstrated that oestrogen treatment may also induce PS gene expression in the male and female rat neurointermediate lobe. None of the other five rat arginyl-esteropeptidase genes so far described (S1, S2, S3, K1, P1) was found to be expressed in the anterior pituitary or neurointermediate lobe under these conditions. However, the demonstration of an additional hybridization signal in the male neurointermediate lobe using a relatively non-specific PS gene probe suggests the expression of another, as yet uncharacterized, kallikrein gene family member in this tissue.
Reconstitution of endogenous interferon a by recombinant interferon in hairy cell leukemia. (2000)

Recombinant human IFN alpha (rhIFN-alpha) plays an important role in the treatment of hairy cell leukemia (HCL). However, the mechanisms leading to its beneficial effect are not completely clarified, and there is no information on IFN-alpha gene expression in this disease. Therefore, we investigated the pattern of IFN-alpha gene expression and protein production in HCL and their potential regulation by rhIFN-alpha. Blood samples from 10 patients with HCL and 8 healthy donors (HD) were investigated. Expression of IFN-alpha mRNA was assessed by reverse transcription-PCR analysis in peripheral blood mononuclear cells (PBMCs) under basal conditions and on induction with rhIFN-alpha and polyionosinic-polycytidylic acid [poly(I.C)]. IFN-alpha concentrations in plasma and culture supernatants were measured by immunoassays, and intracellular IFN-alpha was evaluated by fluorescence-activated cell sorting analysis. Results showed that, in contrast to blood samples from HDs, freshly isolated PBMCs from un treated HCL patients did not express IFN-alpha mRNA, whereas IFN-alpha transcripts were found in patients who were under rhIFN-alpha therapy Plasma of untreated patients contained no, or extremely low levels of IFN-alpha as compared with plasma of treated patients and HDs. Ex vivo treatment of PBMCs with rhIFN-alpha or poly(I.C) resulted in a remarkable up-regulation of IFN-alpha at the mRNA and protein level. In HCL, however the amounts of IFN-alpha protein remained less than in HD. Inhibition of IFN-alpha transcription was found after exposure of PBMCs to serum fron untreated patients. Finally, a reduced capacity to produce IFN-alpha was found within B- cell, T-cell, and monocyte compartments in HCL patients which could be enhanced by rhIFN-alpha. The results demonstrate the ability, of rhIFN-alpha to up-regulate the expression of IFN-alpha gene and protein production and suggest that priming the production of endogenous IFN-alpha is a critical step in the mechanism of action of rhIFN-alpha in HCL.
Manta: Rapid detection of structural variants and indels for clinical sequencing applications (2015)

ABSTRACT Summary We describe Manta, a method to discover structural variants and indels from next generation sequencing data. Manta is optimized for rapid clinical analysis, calling structural variants, medium-sized indels and large insertions on standard compute hardware in less than a tenth of the time that comparable methods require to identify only subsets of these variant types: for example NA12878 at 50x genomic coverage is analyzed in less than 20 minutes. Manta can discover and score variants based on supporting paired and split-read evidence, with scoring models optimized for germline analysis of diploid individuals and somatic analysis of tumor-normal sample pairs. Call quality is similar to or better than comparable methods, as determined by pedigree consistency of germline calls and comparison of somatic calls to COSMIC database variants. Manta consistently assembles a higher fraction of its calls to basepair resolution, allowing for improved downstream annotation and analysis of clinical significance. We provide Manta as a community resource to facilitate practical and routine structural variant analysis in clinical and research sequencing scenarios. Availability Manta source code and Linux binaries are available from http://github.com/sequencing/manta . Contact csaunders@illumina.com Supplementary information Supplementary data are available at Bioinformatics online.
A consistent and accurateab initioparametrization of density functional dispersion correction (DFT-D) for the 94 elements H-Pu (2010)

The method of dispersion correction as an add-on to standard Kohn-Sham density functional theory (DFT-D) has been refined regarding higher accuracy, broader range of applicability, and less empiricism. The main new ingredients are atom-pairwise specific dispersion coefficients and cutoff radii that are both computed from first principles. The coefficients for new eighth-order dispersion terms are computed using established recursion relations. System (geometry) dependent information is used for the first time in a DFT-D type approach by employing the new concept of fractional coordination numbers (CN). They are used to interpolate between dispersion coefficients of atoms in different chemical environments. The method only requires adjustment of two global parameters for each density functional, is asymptotically exact for a gas of weakly interacting neutral atoms, and easily allows the computation of atomic forces. Three-body nonadditivity terms are considered. The method has been assessed on standard benchmark sets for inter- and intramolecular noncovalent interactions with a particular emphasis on a consistent description of light and heavy element systems. The mean absolute deviations for the S22 benchmark set of noncovalent interactions for 11 standard density functionals decrease by 15%-40% compared to the previous (already accurate) DFT-D version. Spectacular improvements are found for a tripeptide-folding model and all tested metallic systems. The rectification of the long-range behavior and the use of more accurate C(6) coefficients also lead to a much better description of large (infinite) systems as shown for graphene sheets and the adsorption of benzene on an Ag(111) surface. For graphene it is found that the inclusion of three-body terms substantially (by about 10%) weakens the interlayer binding. We propose the revised DFT-D method as a general tool for the computation of the dispersion energy in molecules and solids of any kind with DFT and related (low-cost) electronic structure methods for large systems.
Determination of Loudspeaker Driver Parameters Using a System Identification Technique (1987)

A time-domain method for measuring the parameters of linear models of loudspeaker drivers is described. The loudspeaker is excited by a low-pass filtered square-wave voltage or current input. In addition to voltage and current, the cone displacement is measured and recorded by a personal computer. From these data the parameters are estimated by system identification techniques, in particular the least-squares and the instrumental-variable algorithms
A Sensorless Rotor Temperature Estimator for Induction Machines Based on a Current Harmonic Spectral Estimation Scheme (2008)

This paper proposes a sensorless rotor temperature estimator for small- to medium-sized mains-fed induction machines. With measurements obtained only from voltage and current sensors, the proposed estimator can capture the rotor temperature online. The rotor speed is first extracted from the stator current harmonic spectrum based on the estimated rotor slot and eccentricity harmonic frequencies. Then the inductances are estimated according to the induction machine equivalent circuit developed from the rotor flux field orientation. The stator winding resistance at ambient temperature is the only motor parameter needed as input in this stage. Once the inductances are obtained, they are fed into the rotor resistance estimation algorithm to yield an estimate of the rotor resistance. Finally, the rotor temperature is calculated from the linear relationship between the temperature and rotor resistance. The experimental results from different motors are shown to validate the proposed algorithms. The whole scheme is efficient and reliable and is therefore suitable for implementation in a motor overload protection relay to provide thermal protection against rotor overheating.
Calcium carbonate microparticles used as a gene vector for delivering p53 gene into cancer cells (2012)

Calcium carbonate (CaCO(3) ) microparticles were for the first time used for efficient delivery of p53 gene to transfect human cancer cells HeLa. CaCO(3) microparticles (2-4 μm) absorbed pEGFP-C1-p53 (expressing GFP-P53 fusion protein) to transfect HeLa cells. Flow cytometer (FCM) was used to evaluate the gene transfection efficiency in HeLa cells, which were stably transduced with a green fluorescent protein gene. In this study, CaCO(3) delivering pEGFP-C1-p53 could transfect about 5% of the tumor cells in culture. However, the efficiency of tumor cell apoptosis was surprisingly up to 80%. Meanwhile, the results of MTT assay and crystal violet staining showed that the CaCO(3) microparticles had low cytotoxicity. These findings showed that CaCO(3) microparticles were perspective to be used as new vectors for gene therapy.