gebhart/patrepeval huggingface dataset:
Securing ad-hoc networks using IPsec (2005)

The use of IPSec for securing communication between nodes of wireless and mobile ad hoc networks has traditionally been considered difficult. We describe an IPSec-based architecture and implementation for ad hoc networks that can seamlessly handle node mobility and IP address change. The approach can he used for securing application traffic as well as configuration and mobility management protocol traffic. A certificate-based approach that aids dynamic key generation and distribution is used for creating security associations between nodes. Simple and backward compatible extensions to the IPSec and PKIX protocols that do not violate existing and proposed standards are described, and an existing implementation is discussed. Initial experimental evaluation reveals that the per-packet latency overhead at the end-host for using our proposed mechanisms is tolerable.
The road to Crohn's disease (2017)

A stress pathway directs the antimicrobial response to an enteric pathogen
Role of abnormal neutral endopeptidase-like activities inHyp mouse bone cells in renal phosphate transport (2002)

We investigated whether the absence of Phex (phosphate-regulating gene with homologies to endopeptidases on the X chromosome) in the Hyp mouse affects the expression and activity of neprilysin (NEP) and of endothelin-converting enzyme-like endopeptidase (ECEL1/DINE) in bone marrow stromal cells (BMSC) and osteoblasts (Ob). Total NEP-like activity was higher in Ob than in BMSC regardless of genotype, and Hyp cells showed higher activities than normal. Conditioned media (CM) from Hyp BMSC and Ob inhibited inorganic phosphate (P(i)) uptake by mouse proximal tubule cells, and incubating Hyp Ob with phosphoramidon prevented the production of the inhibitor of renal P(i) uptake. A linear relationship was observed between the NEP-like activity of Hyp and normal cells and the inhibition of P(i) uptake. NEP and ECEL1/DINE mRNA levels were higher in Hyp cells than in normal cells, and in situ hybridization of ECEL1/DINE confirmed higher levels of expression in the Hyp mouse than in normal cells. In conclusion, we observed a correlation between the inhibition of P(i) uptake by CM from Hyp cells and elevated NEP-like activities.
Nonaqueous synthesis of nanosilica in epoxy resin matrix and thermal properties of their cured nanocomposites (2005)

Abstract Nonaqueous synthesis of nanosilica in diglycidyl ether of bisphenol‐A epoxy (DGEBA) resin has been successfully achieved in this study by reacting tetraethoxysilane (TEOS) directly with DGEBA epoxy matrix, at 80 °C for 4 h under the catalysis of boron trifluoride monoethylamine (BF 3 MEA). BF 3 MEA was proved to be an effective catalyst for the formation of nanosilica in DGEBA epoxy under thermal heating process. FTIR and 29 Si NMR spectra have been used to characterize the structures of nanosilica obtained from this direct thermal synthetic process. The morphology of the nanosilica synthesized in epoxy matrix has also been analyzed by TEM and SEM studies. The effects of both the concentration of BF 3 MEA catalyst and amount of TEOS on the diameters of nanosilica in the DGEBA epoxy resin have been discussed in this study. From the DSC analysis, it was found that the nanosilica containing epoxy exhibited the same curing profile as pure epoxy resin, during the curing reaction with 4,4′‐diaminodiphenysulfone (DDS). The thermal‐cured epoxy–nanosilica composites from 40% of TEOS exhibited high glass transition temperature of 221 °C, which was almost 50 °C higher than that of pure DGEBA–DDS–BF 3 MEA‐cured resin network. Almost 60 °C increase in thermal degradation temperature has been observed during the TGA of the DDS‐cured epoxy–nanosilica composites containing 40% of TEOS. © 2005 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 44: 757–768, 2006
Editorial: Immunotherapy in renal cell carcinoma (2022)

This collection contains 10 reports published In Frontiers in Oncology between August 2020 and March 2022 broadly focused on the immunobiology of renal cell carcinoma (RCC), the impact of immunotherapy in the setting of RCC, and the identification of biomarkers that are prognostic of RCC patient outcomes and response to immunotherapy.
Performance Improvement of an Ad Hoc Network System for Wireless Data Service (2003)

this paper, we first evaluate the performance through simulations for data-link protocol and routing protocol of FRN to clarify its basic properties, and then we discover some problems that degrade the performance. Furthermore, we propose some performance improvement techniques. They are methods to set an adaptive system parameter or to improve its protocol statically. We simulate those techniques and show how they improve the system performance
Fibronectin involvement in granulation tissue and wound healing in rabbits. (1982)

This study describes the distribution of fibronectin and its association with reticulin fibers (type III collagen) and hyaluronic acid in shallow rabbit wounds. Linear incisions were made dorsally with a surgical blade. Animals were sacrificed and 1,2,3,4,5, and 8 day wounds were examined using peroxidase-antiperoxidase to localize affinity-purified antibodies to fibronectin. Tissue samples were also stained with hematoxylin and eosin in addition to silver stains for reticulin, and Alcian blue for hyaluronic acid. After wounding, the incision filled with a fibrin clot that stained positively for fibronectin. The underlying dermis and adjacent, unwounded dermis also contained fibronectin. Epidermal cells that migrate from the wound margin between the clot and the dermis were in direct association with fibronectin in these wound components. By 72 hr, epidermal continuity was reestablished. Early granulation tissue formation was apparent just below the epidermis 5 day wounds. Fibronectin was observed in the matrix surrounding individual fibroblasts and codistributed with reticulin fibers and hyaluronic acid in both 5 and 8 day wounds. Granulation tissue of 8 day wounds stained intensely for fibronectin and extended to a greater depth in the reticular dermis. Dense fibrillar networks of fibronectin and fibroblasts were aligned parallel to the epidermis, giving the granulation tissue a highly structured and organized appearance. Fibroblasts contained fibronectin and were surrounded by less fibronectin at the wound periphery than within the granulation tissue. These findings suggest that fibronectin may be important in the reconstruction of tissues during repair by functioning as an extracellular scaffold for migrating cells.
Splitting the solar radiation in direct and diffuse components; insights and constrains on the clearness-diffuse fraction representation (2017)

In many engineering applications, it is mandatory to know separately the solar radiation diffuse and direct components. Examples regard the assessment of the energy potentially exploitable by a system of solar thermal or photovoltaic panels and, in general, all the cases where it is necessary to calculate the radiative solar power collected by a surface. In fact, radiation components will differently project on the surface of interest and will weigh in a different manner, depending on the surface orientation, in the computation of the effective incident radiation. To perform this decomposition starting from data relative to a horizontal plane, two non-dimensional quantities, namely, the diffuse fraction, kd, and the clearness, kt, are usually put in mutual relation by correlating experimental data on a graphical ground rather than using physical considerations. In the present study, some insights are given on the shape of this correlation starting from geometric and physical considerations. It is shown that many results and graphs presented in literature have not physical meaning; rather they are simply artifacts due to geometrical or other constraints. These evidences open the way to a new approach to solar radiation decomposition founded on physical-based correlations.
The Solubility of Soaps and of Some Salts in Mixtures of Solvents, One of Which Is of Glycolic Type (1947)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Solubility of Soaps and of Some Salts in Mixtures of Solvents, One of Which Is of Glycolic TypeSanti R. PalitCite this: J. Am. Chem. Soc. 1947, 69, 12, 3120–3129Publication Date (Print):December 1, 1947Publication History Published online1 May 2002Published inissue 1 December 1947https://pubs.acs.org/doi/10.1021/ja01204a056https://doi.org/10.1021/ja01204a056research-articleACS PublicationsRequest reuse permissionsArticle Views1044Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Electrostatically-tuned Optical Filter Based on Silicon Bragg Reflectors (2006)

A tunable Fabry-Perot cavity composed of two Bragg mirrors is realized using enhanced deep reactive ion etching (DRIE) process. Filter tuning is achieved by moving one of the mirrors using a high resolution electrostatic actuator over SOI. Measured filter response in C&L bands is presented
Risk of Hemolytic Uremic Syndrome After Antibiotic Treatment of Escherichia coli O157:H7 Enteritis (2002)

Our meta-analysis did not show a higher risk of HUS associated with antibiotic administration. A randomized trial of adequate power, with multiple distinct strains of E coli O157:H7 represented, is needed to conclusively determine whether antibiotic treatment of E coli O157:H7 enteritis increases the risk of HUS.
Vertical Bipolar Transistor Test Structure for Measuring Minority Carrier Lifetime in IGBTs (2019)

Vertical PNP bipolar transistor test structures were fabricated, which can be integrated on the same wafer with functional IGBTs. Common-base current gain was measured by applying zero voltage to the leaky back side junction, from which minority carrier lifetime in the base region was extracted. The structure makes it possible to measure the lifetime after a real IGBT fabrication process flow, and to correlate it with the characteristics of IGBTs on the same wafer.
Test campaign of a ducted wind turbine in real operating conditions (2019)

Wind turbine installation worldwide has increased at unrested pace, as it represents a 100% clean energy with zero CO 2 and pollutant emissions. However, visual and acoustic impact of wind turbines is still a drawback, in particular in urban areas. This paper focuses on the performance evaluation of an innovative horizontal axis ducted wind turbine, installed in the harbour of Genova (Italy) in 2018: the turbine was designed in order to minimize visual and acoustic impacts and maximize electrical energy production, also during low wind speed periods. The preliminary study and experimental analyses, performed by the authors in a previous study, showed promising results in terms of energy production, compared to a traditional generator ( factor &gt;2.5 on power output). In the present paper, the test campaign on a scaled-up prototype, installed in the urban area of Genova, is performed, with a twofold objective: (i) comparison of the ducted innovative turbine with a standard one, in order to verify the increase in energy production; (ii) analysis of the innovative turbine for different wind speeds and directions, evaluating the influence of ambient conditions on performance. Finally, based on the obtained results, an improved setup is proposed for the ducted wind turbine, in order to further increase energy production mitigating its visual impact.
Design and Analysis of Drug Combination Experiments (2005)

In this paper we present and discuss a novel, simple and easy to implement parametric modeling approach to assess synergy. An extended three parameter log-logistic model is used to analyse the data and calculate confidence intervals of the interaction indices. In addition the model corrects for the bias due to plate-location effects. The analysis is performed with PROC NLMIXED and SAS-code is provided. The approach is illustrated using data coming from an oncology study in which the inhibition effect of a combination of two compounds is studied using 96-well plates and a fixed-ratio design.
Maritime autonomy in a box: Building a quickly-deployable autonomy solution using the Docker container environment (2016)

We present a method to dramatically reduce the level of effort and lead time required to take autonomy algorithms from initial development to field experiments when using shared assets. The method leverages the Docker containerization environment coupled with automatic configuration and deployment modules and a standardized autonomy framework. The result is a quickly-deployable, easily reconfigurable, and vehicle-agnostic autonomy solution for use when assets are shared and repeatedly re-baselining the system is necessary. For an initial implementation of the containerization system, we leverage the Mission-Oriented Operating Suite - Interval Programming autonomy framework.
Antioxidative, hypoglycaemic and hepatoprotective properties of five Vaccinium spp. berry pomace extracts (2019)

BACKGROUND: Berry pomaces contain biologically active substances and therefore may have considerable potential applications in food and pharmaceutical industries. However, there is a lack of studies on extracting these valuable products from berry pomaces. OBJECTIVE: This study aims to evaluate major constituents of five Vaccinium spp. berry pomace extracts and investigate their antioxidant, hypoglycaemic and hepatoprotective properties. METHODS: Total anthocyanin, procyanidin and polyphenol contents in berry residues were measured by spectrophotometric pH-differential, 4-dimethylaminocinnamaldehyde and Folin–Ciocalteu method, respectively. Identification and quantification of separate compounds were assessed by ultra-performance liquid chromatography and liquid chromatography-time-of-flight-masspectroscopy. Anti-hyperglycaemic properties of pomace extracts were evaluated based on inhibition of α-amylase and α-glucosidase activity. Extract hepatoprotective effects were estimated based on increased human hepatic cell line HepG2 viability in oxidative stress conditions. RESULTS: The extracts possessed strong antioxidant effects and efficacy for inhibiting the activities of enzymes involved in carbohydrate digestion and for protecting hepatic cells from oxidative damage. CONCLUSIONS: Hepatoprotective and hypoglycaemic properties of berry pomace extracts may be due to the presence of active polyphenols and their synergistic effects. Our results support the use of berry pomaces for designing standardised formulations for the prevention of chronic diseases associated with oxidative stress.
Clinical grade isolation of regulatory T cells from G-CSF mobilized peripheral blood improves with initial depletion of monocytes. (2015)

Clinical isolation of circulating CD4(+)CD25(+) regulatory T cells (Tregs) from peripheral blood mononuclear cells is usually performed by CD4(+) cell negative selection followed by CD25(+) cell positive selection. Although G-CSF mobilized peripheral blood (G-PBSC) contains a high number of Tregs, a high number of monocytes in G-PBSC limits Treg isolation. Using a small scale device (MidiMACS, Miltenyi) we initially demonstrated that an initial depletion of monocytes would be necessary to obtaina separation of CD4(+)CD25(+)FoxP3(+)CD127(-) cells from G-PBSC (G-Tregs) with a consistent purity >70% and inhibitory activity of T cell alloreactivity in-vitro. We then validated the same approach in a clinical scale setting by separating G-Tregs with clinically available antibodies to perform a CD8(+)CD19(+)CD14(+) cell depletion followed by CD25(+) cell selection (2-step process) or by adding an initial CD14(+) cell depletion (3-step process) using a CliniMACS column. The 3-step approach resulted in a better purity (81±12% vs. 35±33%) and yield (66% vs. 39%). Clinically isolated G-Tregs were also FoxP3(+)CD127(dim) and functionally suppressive in-vitro. Our findings suggest that a better and more consistent purity of Tregs can be achieved from G-PBSC by an initial single depletion of monocytes prior to selection of CD4(+)CD25(+) cells.
Toward Resilient Task Parallel PDE Solvers. (2018)

Abstract not provided.
Crashes and Fatalities Related to Driver Drowsiness/Fatigue (1994)

This report summarizes recent national statistics on the incidence and characteristics of crashes involving driver fatigue, drowsiness, or asleep-at-the-wheel. For the purposes of this report, these terms are considered synonymous. Principal data sources are the NHTSA General Estimates System (GES) and the Fatal Accident Reporting System (FARS), although these data files are acknowledged to have limitations for quantifying this type of crash causal factor. Most data provided are for the five-year period 1989-93. Findings from other studies of the incidence of drowsiness/fatigue in crashes are reviewed. Finally, overviews are provided of NHTSA programs underway to help provide better data to assess this traffic safety problem and, more importantly, to develop effective countermeasures.
Supplementary Table 1 from Breast Cancer Cells Isolated by Chemotaxis from Primary Tumors Show Increased Survival and Resistance to Chemotherapy (2023)

Supplementary Table 1 from Breast Cancer Cells Isolated by Chemotaxis from Primary Tumors Show Increased Survival and Resistance to Chemotherapy
Overtaking vehicles detection and localization for driver assistance (2014)

This paper proposed an effective overtaking vehicle detection and localization system based on wheel detection. Using the windshield-mounted camera, it can detect the vehicles in rear-view and side-view. It extracts the MB-LBP feature for the cascaded Adaboost classifiers. Differing from traditional approaches, our method can overcome the perspective variation of the wheels in the images. It can detect the wheels of different aspect rations with varying scales. After wheel detection, it can locate the overtaking vehicle by pairing the front/rear wheels. The experiments show that our system can identify and locate the vehicle appearing in side-view as well as in rear-view. The performance of wheel detector is demonstrated with the precision rate as 0.91 and recall rate as 0.96.
The Lithovac: New Suction Device for the Swiss Lithoclast (1995)

Minimal invasiveness characterizes modern stone therapy. Several years ago, we presented the Swiss Lithoclast, a ballistic system for endoscopic stone therapy. Its disintegrational power is superior to that of the other intracorporeal lithotripsy devices, and it has gained great recognition. Now, special probes (Lithovac) have been developed to combine lithotripsy with suction. These probes differ in width (1.6, 3.5, or 4 mm) and length depending on the intended location of use (kidney, ureter, bladder). The probes were tested in a standardized stone model. The variable suction energy counteracts the propulsive energy of the Lithoclast. Clinical experience could be gained with stones in the urinary bladder, Kock pouches, the ureter, and the kidney. There were no complications related to either the Lithoclast or the Lithovac. In staghorn stones, small (< 2 mm) pieces could be removed easily during lithotripsy. Fragments as large as 3.5 mm could be evacuated with the Lithovac after removing the Lithoclast probe. Using the suction, clear vision could be achieved (especially useful in struvite stones). In the ureter, a learning curve had to be overcome to balance fluid inflow and suction pressure. Otherwise, the ureter may collapse. However, this was possible in all patients. Using the single-shot mechanism, stones were broken up fast. The fragments could be dragged to the Lithoclast probe with the Lithovac. No pushback happened. In bladder and Kock pouch stones, suction may not be enough to hold the stone to the probe, but it is of great value to keep a small volume in the bladder/pouch and still have excellent visibility. The Lithovac is a useful tool in all endoscopic applications of the Lithoclast.
Using Freshwater Mussels as an Indicator for River Water Quality (2017)

Using the freshwater mussel to monitor water quality is a practical and advantageous way to use nature’s indicator species. River water quality is an important measurement that is constantly monitored for many purposes. The sampling involved with monitoring can be very costly and time-consuming. Using mussels as indicator species could save money and time. So, this project has been dedicated to exploring the applications and reality of using freshwater mussels to monitor river quality.
Sensors based on conductive polymers and their composites: a review (2019)

Abstract Conductive polymers (CPs) for sensors present numerous advantages such as high sensitivity, short response time, room temperature operation, and the possibility of tuning both chemical and physical properties by using different substituents. Therefore, sensors based on CPs and their composites have attracted much attention from researchers. The CPs used for sensors mainly consist of polyaniline, polypyrrole and poly(3,4‐ethylenedioxythiophene) etc. In this review, the fabrication, sensing performance, mechanism and perspectives of sensors based on CPs and their composites are thoroughly summarized. The CPs and their thin films were prepared under different polymerization conditions and used as various sensors. CP composites combine the advantages of CPs and other sensing materials such as carbonaceous materials, metal oxides, metals etc., and their sensors demonstrate a high sensing performance due to the synergistic effect of the components. Finally, the perspectives and development trends of sensors based on CPs and their composites are introduced. © 2019 Society of Chemical Industry
The Role of Protein Kinase D in Neurotensin Secretion Mediated by Protein Kinase C-α/-δ and Rho/Rho Kinase (2004)

Neurotensin (NT) is a gut peptide that plays an important role in gastrointestinal (GI) secretion, motility, and growth as well as the proliferation of NT receptor positive cancers. Secretion of NT is regulated by phorbol ester-sensitive protein kinase C (PKC) isoforms-alpha and -delta and may involve protein kinase D (PKD). The purpose of our present study was: (i) to define the role of PKD in NT release from BON endocrine cells and (ii) to delineate the upstream signaling mechanisms mediating this effect. Here, we demonstrate that small interfering RNA (siRNA) targeted against PKD dramatically inhibited both basal and PMA-stimulated NT secretion; NT release is significantly increased by overexpression of PKD. PKC-alpha and -delta siRNA attenuated PKD activity, whereas overexpression of PKC-alpha and -delta enhanced PKD activity. Rho kinase (ROK) siRNA significantly inhibited NT secretion, whereas overexpression of ROKalpha effectively increased NT release. Rho protein inhibitor C3 dramatically inhibited both NT secretion and PKD activity. In conclusion, our results demonstrate that PKD activation plays a central role in NT peptide secretion; upstream regulators of PKD include PKC-alpha and -delta and Rho/ROK. Importantly, our results identify novel signaling pathways, which culminate in gut peptide release.