gebhart/patrepeval huggingface dataset:
Droplet Combustion Experiments Aboard the International Space Station (2014)

This paper summarizes the first results from isolated droplet combustion experiments performed on the International Space Station (ISS). The long durations of microgravity provided in the ISS enable the measurement of droplet and flame histories over an unprecedented range of conditions. The first experiments were with heptane and methanol as fuels, initial droplet droplet diameters between 1.5 and 5.0 m m, ambient oxygen mole fractions between 0.1 and 0.4, ambient pressures between 0.7 and 3.0 a t m and ambient environments containing oxygen and nitrogen diluted with both carbon dioxide and helium. The experiments show both radiative and diffusive extinction. For both fuels, the flames exhibited pre-extinction flame oscillations during radiative extinction with a frequency of approximately 1 H z. The results revealed that as the ambient oxygen mole fraction was reduced, the diffusive-extinction droplet diameter increased and the radiative-extinction droplet diameter decreased. In between these two limiting extinction conditions, quasi-steady combustion was observed. Another important measurement that is related to spacecraft fire safety is the limiting oxygen index (LOI), the oxygen concentration below which quasi-steady combustion cannot be supported. This is also the ambient oxygen mole fraction for which the radiative and diffusive extinction diameters become equal. For oxygen/nitrogen mixtures, the LOI is 0.12 and 0.15 for methanol and heptane, respectively. The LOI increases to approximately 0.14 (0.14 O 2/0.56 N 2/0.30 C O 2) and 0.17 (0.17 O 2/0.63 N 2/0.20 C O 2) for methanol and heptane, respectively, for ambient environments that simulated dispersing an inert-gas suppressant (carbon dioxide) into a nominally air (1.0 a t m) ambient environment. The LOI is approximately 0.14 and 0.15 for methanol and heptane, respectively, when helium is dispersed into air at 1 atm. The experiments also showed unique burning behavior for large heptane droplets. After the visible hot flame radiatively extinguished around a large heptane droplet, the droplet continued to burn with a cool flame. This phenomena was observed repeatably over a wide range of ambient conditions. These cool flames were invisible to the experiment imaging system but their behavior was inferred by the sustained quasi-steady burning after visible flame extinction. Verification of this new burning regime was established by both theoretical and numerical analysis of the experimental results. These innovative experiments have provided a wealth of new data for improving the understanding of droplet combustion and related aspects of fire safety, as well as offering important measurements that can be used to test sophisticated evolving computational models and theories of droplet combustion.
Should You Accept a Friends Request From Your Mother? And Other Filipino Dilemmas (2012)

Abstract: This paper uses the concept of ‘cutting the network’ derived from the work of Marilyn Strathern to examine the relationship between two kinds of social network, that of kinship and the system of friends constructed on social networking sites. Specifically the material comes from a study of Filipina domestic workers and nurses in the UK and their relationship to their left behind children in the Philippines. A bilateral system of kinship can lead to a proliferation of relatives, while the use of the Friendster social networking site can lead to a proliferation of friends. It is when these two systems clash following the request by one's mother to become a friend that the constraints and problems posed by both systems comes into view. Cases show that it is possible to use social networking sites to help mothers become close friends for their absent children, but more commonly the increasing presence of actual mothers through new media disrupts the relationships that children had developed for themselves to a idealised projection of motherhood.
Enhanced photoelectrochemical performance of internally porous Au-embedded α-Fe2O3 photoanodes for water oxidation (2017)

We report internally porous Au-embedded hematite on FTO using CTAB. Incorporation of Au and CTAB synergistically improved the photocurrent of hematite by 63% at 1.23 V<sub>RHE</sub> in 1 M NaOH under standard illumination conditions. The performance enhancement is due to the increased donor density and optical properties of internally porous networks and plasmonic absorption of hematite.
Modulation of glycosphingolipid metabolism significantly improves hepatic insulin sensitivity and reverses hepatic steatosis in mice # (2009)

Pharmacological lowering of glycosphingolipids with the iminosugar AMP-DNM is a promising approach to restore insulin signaling and improve glucose homeostasis as well as hepatic steatosis.
Is Vegas-Style Solitaire Fair? (2001)

When stationary phase Escherichia coli K12 trp (amber) cells were exposed to UV doses ranging from 180-540 J m(-2), we found that we could not recover any induced Trp+ revertants unless the irradiated cultures were first supplied with the Muc+ mutation-enhancing IncP plasmid pKM101 (by conjugation). We also found that the numbers of UV-induced Trp+ revertants recovered from pKM101+ cultures varied quite dramatically depending upon which of several commonly-used carbon sources were present in the post-irradiation plating medium, e.g., there were always significantly fewer revertants on minimal glucose plates than on minimal glycerol plates. More importantly, there were also fewer UV-induced revertants on glycerol + glucose plates than on 'glycerol-only' plates. We then tested two glucose-related compounds which are known to depress intracellular cyclic AMP (cAMP) levels even more effectively than glucose (glucose-6-phosphate and the non-utilisable methyl-alpha-D-glucopyranoside) and found that they too were able to exert powerfully antimutagenic effects in UV-treated pKM101-containing bacteria. Taken together, these results provide strong additional support for our working hypothesis that at least one component of the mutational pathway which operates in UV-irradiated pKM101-containing cells is extremely sensitive to classical cAMP-mediated catabolite repression.
SQL Injection: Modes of attack, defence, and why it matters (2002)

SQL injection attacks represent a serious threat to any database-driven site. The methods behind an attack are easy to learn and the damage caused can range from considerable to complete system compromise. Despite these risks an incredible number of systems on the internet are susceptible to this form of attack. Not only is it a threat easily instigated, it is also a threat that, with a little common-sense and forethought, can be almost totally prevented. This paper will look at a selection of the methods available to a SQL injection attacker and how they are best defended against.
Feasibility Analysis of Gob-Side Entry Retaining in Steep Coal Seam (2013)

It's one of the key factors of utilizing the technology of gob-side entry retaining in steep coal seam that safely and effectively prevent caving rock blocks from rushing into the gob-side entry by sliding downwards along levels. Considering steep coal seam, mining process in fully-mechanize face is numerically simulated, the stress and deformation process of roof strata is analyzed, the difficulty of utilizing the technology is considered, which all are combined with practice in steep working face in Lvshuidong Mine. The feasibility analysis of utilizing the technology of gob-side entry retaining in steep coal seam is obtained.
Low-temperature MOCVD of chromium carbonitride coatings from tetrakis(diethylamido)chromium and pyrolysis mechanism of this single-source precursor (1998)

Amorphous chromium carbonitride coatings with a low nitrogen content (3–8 at%) were deposited by low-pressure MOCVD in the temperature range 573–793 K using Cr(NEt2)4 as single-source precursor. This poor nitrogen incorporation is in agreement with the trends predicted by thermochemical calculations. XPS data, resistivity measurements and annealing experiments suggest that the films grown at 573 K are contaminated by organic species due to incomplete elimination of the ligands. The films deposited at higher temperature crystallize upon annealing at 873 K to form an orthorhombic ternary chromium carbonitride phase. The major volatile by-products of the MOCVD reaction were analyzed by 1H and 13C NMR. Their amount and the quasi-equimolar EtN=CHMe/HNEt2 ratio suggest that most of the NEt2 ligands are removed by a stepwise mechanism which probably occurs with other diethylamido complexes of transition metals when they are used as single-source precursors in MOCVD. The incorporation of the metalloid elements in the film is discussed in comparison with recent literature data. © 1998 John Wiley & Sons, Ltd.
Letters: When EVs age (1996)

ADVERTISEMENT RETURN TO ISSUEPREVDepartmentsNEXTLetters: When EVs ageDonald H. StedmanCite this: Environ. Sci. Technol. 1996, 30, 12, 517APublication Date (Web):June 7, 2011Publication History Published online7 June 2011Published inissue 1 November 1996https://pubs.acs.org/doi/10.1021/es962489vhttps://doi.org/10.1021/es962489vresearch-articleACS PublicationsRequest reuse permissionsArticle Views19Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ECC-1 Cells: A Well-Differentiated Steroid-Responsive Endometrial Cell Line with Characteristics of Luminal Epithelium1 (2006)

Endometrial cancer cell lines have provided a valuable model to study endometrial epithelial cells in vitro. Since the first development of HEC1B over 35 yr ago, many different cell lines have been isolated and described. One valuable cell line that maintains hormone responsiveness and unique stability over time is the ECC-1 cell line, developed originally by the late P.G. Satyaswaroop. In this study, we investigated some of the properties of these cells and present their salient characteristics. Like Ishikawa cells, ECC-1 cells maintain both estrogen receptors (ESR1 [ER alpha] and ESR2 [ER beta]), progesterone receptors (PR A and B; PGRs), and androgen receptors (ARs), along with the p160 steroid receptor coactivators NCOA1 (formerly SRC1), NCOA2 (formerly TIF2), and NCOA3 (formerly AIB1). The karyotype of these cells is abnormal, with multiple structural rearrangements in all cells analyzed. Unlike Ishikawa cells that express glandular epithelial antigens, ECC-1 cells maintain a luminal phenotype, with expression of KRT13 (cytokeratin 13) and KRT18 (cytokeratin 18). Apparent differences in the regulation of ESR2 also were evident in ECC-1 cells compared to Ishikawa cells. Like other endometrial cell lines, ECC-1 cells express the steroid receptor coactivators and exhibit epidermal growth factor-stimulated expression of known luminal proteins thought to be involved in implantation, including the hyaluronate receptor CD44 and SPP1 (formerly osteopontin) and CD55 (decay-accelerating factor). These characteristics appear to be stable and persistent over multiple cell passages, making this well-differentiated cell line an excellent choice to study endocrine and paracrine regulation of endometrial epithelium in vitro.
Circuit Design for Discrete‐Time Delta‐Sigma ADCs (2017)

This chapter examines circuits for switched-capacitor sigma-delta analog-to-digital converters (ADCs), using a simple low-speed 1-bit second-order modulator to illustrate the primary design considerations. An ADC having a bandwidth of 1 kHz could be used as an on-chip voltage monitor or as part of a low-speed calibration engine. The designer should ensure that the amplifier has enough input common-mode range to accommodate such errors. The folding connection between the output of the differential pair and the source of the opposite-polarity cascodes provides a wide input common-mode range, while the cascaded current sources in the output legs provide a high output impedance and hence high opamp gain. Behavioral modeling can be used to quantify the distortion resulting from a given gain curve, but it is more direct, and usually easier, to rely on transistor-level simulations of the amplifier in the context of the modulator. The second amplifier can be a scaled-down version of the first amplifier. The capacitors in the second stage are so much smaller than those in the first stage that a scaling factor of 10x appears reasonable.
ChemInform Abstract: Vicarious Nucleophilic Substitution of Hydrogen Proceeding via Heterocyclic Ring Opening. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A Multicenter Study of Antifungal Use and Species Distribution and Antifungal usceptibilities of Candida Isolates in South Korea (2020)

Background: Candidiasis control should include monitoring the epidemiology and resistance to various antifungal agents. In this study, the researchers investigated the Candida species recovered from clinical specimens at particular geographic areas or hospitals. Objective: The present study is geared toward the evaluation of antifungal drug usage at Korean hospitals in 2016. It is also essential that species distribution and antifungal susceptibilities of Candida isolates should be looked into to provide important data that can help devise therapeutic strategies to control the disease. Methods: Systemic antifungal agent usage over a one-year period was investigated at 10 Korean hospitals. Identification and antifungal susceptibility tests were performed on clinical isolates of the Candida species, which were collected over a three-month period. Results: The total antifungal usage in each hospital ranged from 7.7 to 158.9 defined daily doses (DDDs) per 1,000 patient days. Fluconazole was most commonly used (37.1%), followed by amphotericin B (30.6%), itraconazole (9.7%), echinocandins (8.8%), voriconazole (7.5%), and posaconazole (6.3%), respectively. Among 274 Candida isolates, C. albicans was the most frequently recovered (51.1%), followed by C. glabrata (15.7%), C. tropicalis (15.0%), and C. parapsilosis (13.5%), respectively. Through the application of either species-specific clinical breakpoints or epidemiological cutoff values to Candida isolates, the non-susceptibility rates to fluconazole, voriconazole, amphotericin B, and micafungin were found in 20.7%, 5.6%, 0%, and 0% of isolates, respectively. Conclusion: This nationwide multicenter study showed that total antifungal use varied considerably according to each hospital. Non-susceptibility to fluconazole should be further monitored, considering the drug's frequent use in Korea.
Metal–Ligand Cooperation by Aromatization–Dearomatization: A New Paradigm in Bond Activation and “Green” Catalysis (2011)

In view of global concerns regarding the environment and sustainable energy resources, there is a strong need for the discovery of new, green catalytic reactions. For this purpose, fresh approaches to catalytic design are desirable. In recent years, complexes based on "cooperating" ligands have exhibited remarkable catalytic activity. These ligands cooperate with the metal center by undergoing reversible structural changes in the processes of substrate activation and product formation. We have discovered a new mode of metal-ligand cooperation, involving aromatization-dearomatization of ligands. Pincer-type ligands based on pyridine or acridine exhibit such cooperation, leading to unusual bond activation processes and to novel, environmentally benign catalysis. Bond activation takes place with no formal change in the metal oxidation state, and so far the activation of H-H, C-H (sp(2) and sp(3)), O-H, and N-H bonds has been demonstrated. Using this approach, we have demonstrated a unique water splitting process, which involves consecutive thermal liberation of H(2) and light-induced liberation of O(2), using no sacrificial reagents, promoted by a pyridine-based pincer ruthenium complex. An acridine pincer complex displays unique "long-range" metal-ligand cooperation in the activation of H(2) and in reaction with ammonia. In this Account, we begin by providing an overview of the metal-ligand cooperation based on aromatization-dearomatization processes. We then describe a range of novel catalytic reactions that we developed guided by these new modes of metal-ligand cooperation. These reactions include the following: (1) acceptorless dehydrogenation of secondary alcohols to ketones, (2) acceptorless dehydrogenative coupling of alcohols to esters, (3) acylation of secondary alcohols by esters with dihydrogen liberation, (4) direct coupling of alcohols and amines to form amides and polyamides with liberation of dihydrogen, (5) coupling of esters and amines to form amides with H(2) liberation, (6) selective synthesis of imines from alcohols and amines, (6) facile catalytic hydrogenolysis of esters to alcohols, (7) hydrogenolysis of amides to alcohols and amines, (8) hydrogenation of ketones to secondary alcohols under mild hydrogen pressures, (9) direct conversion of alcohols to acetals and dihydrogen, and (10) selective synthesis of primary amines directly from alcohols and ammonia. These reactions are efficient, proceed under neutral conditions, and produce no waste, the only byproduct being molecular hydrogen and/or water, providing a foundation for new, highly atom economical, green synthetic processes.
Simultaneous video and thermal imaging of cryogen spray cooling (2000)

In order to understand better the dynamic interaction of cryogen spray cooling of skin, video and thermal images were obtained simultaneously. The cryogen spurt was applied either to skin phantoms (gelatin, 70% water by mass) or in vivo human skin; imaging was performed with a CCD camera (30 frames per second) and a high-speed infrared camera (100 - 850 frames per second). Acquired thermal images were compared to visible images, and a time sequence of different events (ice formation, ice temperature changes, etc.) was developed and used as an input into computer models to provide a more realistic estimation of cryogen spray cooling dynamics. Ice formation, which was present for durations on the order of seconds, had the greatest effect on the theoretical temperature distribution.
Distinct molecular forms of human T cell receptor gamma/delta detected on viable T cells by a monoclonal antibody. (1988)

A second type of TCR molecule has been identified on human and murine T lymphocytes, which involves the protein products of the gamma and delta genes. T lymphocytes bearing this receptor may constitute a separate cell lineage with a distinct immune function. We have produced an mAb, which specifically detects human TCR-gamma/delta in native as well as denatured states, this in contrast to previously used anti-gamma chain peptide sera, which only reacted with denatured protein. The receptor occurs in different molecular forms, with or without interchain disulphide bonds, in which a delta chain may or may not be detected by cell surface iodination. The mAb is reactive with all these receptor forms. Therefore, this antibody could be used to determine the expression of TCR-gamma/delta on viable human T lymphocytes. In normal individuals, TCR-gamma/delta was found on a subset composing 2-7% of CD3+ lymphocytes in peripheral blood and 0.1-1.0% in thymus. The majority of these cells do not express the CD4 or CD8 antigens, although a significant percentage of CD8+ cells was found. TCR-gamma/delta+ cells in peripheral blood are resting lymphocytes, as judged by ultrastructural analysis. T cell clones with different receptor types can display MHC-nonrestricted cytolytic activity, which is shown to be induced by the culture conditions, most likely by growth factors such as IL-2. This strongly suggests that TCR-gamma/delta does not play a role in target cell recognition in MHC-nonrestricted cytotoxicity. The anti-TCR-gamma/delta antibody can specifically induce cytotoxic activity in clones expressing the receptor, but in addition inhibit growth factor induced cytotoxicity, which indicates a regulatory role of the TCR-gamma/delta/CD3 complex in MHC-nonrestricted cytotoxicity.
Azabicyclo Compounds—XI. A study of the fragmentation processes of quinuc‐lidine and some of its derivatives (1972)

Abstract The mass spectra of quinuclidine, all the ring position deuterated analogues and some methyl homologues have been measured. Plausible mechanistic interpretations of principal fragment ions are discussed, in the case of quinuclidine, with the help of deuteration in all the ring positions.
Accumulation of high-molecular-weight amylose in Alzheimer's disease brains (2004)

Although most of the glucose metabolized in the brain is taken up from the blood, glucose derived from glycogen stores is increasingly implicated in both normal brain function and injury repair. An impaired glucose metabolism is one of the features of Alzheimer's disease (AD) entailing a reduction in glucose transporters and the uptake of glucose as well as alterations in the specific activity of glycolytic enzymes. Here we report that AD brains accumulate amylose, the unbranched alpha(1,4)-linked glucose polymer that is resistant to degradation by glycolytic enzymes. Neutral polysaccharides harvested from postmortem brains were purified with hydrazinolysis, ion exchange, and sizing chromatography and subjected to NMR spectroscopy, GC, GC-MS, and methylation analysis. Five percent of the polysaccharides (50 micro g [0.3 micro mol]/g wet weight brain tissue) consisted of amylose with molecular weights exceeding 600,000 Da. There is no evidence for 1,6-branching, indicating that the polymer is not a form of high-molecular-weight glycogen. By GC analysis, the glucose content of the AD brains was almost three times greater than that of the age-matched control brains. A synthesis of amylose in AD brains at the expense of glycogen would compromise glucose metabolism and enhance neural degeneration.
Natural Product Evodiamine with Borate Trigger Unit: Discovery of Potent Antitumor Agents against Colon Cancer (2020)

In order to improve the antitumor potency of the natural product evodiamine, novel boron-containing evodiamine derivatives were designed by incorporating boronic acid and boronate as trigger units. Boronate derivative <b>13a</b> could be triggered by reactive oxygen species (ROS) in the HCT116 colon cancer cell line and showed excellent antitumor activity <i>in vitro</i> and <i>in vivo</i>. It induced apoptosis in HCT116 cancer cells in a dose-dependent manner and cell growth arrest at the G2 phase.