gebhart/patrepeval huggingface dataset:
Integrated Capture and Conversion of CO2 to Methanol in a Post‐Combustion Capture Solvent: Heterogeneous Catalysts for Selective CN Bond Cleavage (Adv. Energy Mater. 46/2022) (2022)

Heterogeneous Catalysts In article number 2202369, Robert A. Dagle, David J. Heldebrant, and co-workers identify a catalytic system for selective C-N cleavage to produce methanol from captured CO2 via the IC3M platform. Integrated capture and conversion of CO2 to materials (IC3M) is an adaptable platform technology, which integrates solvent-based capture and catalytic conversion to produce CO2-derived chemicals.
Is radiotherapy the missing link to enhancing the outcomes in non-small cell lung cancer patients treated with immunotherapy? (2018)

Abstract: Significant improvements in outcomes for locally advanced and metastatic non-small cell lung cancer (NSCLC) have been seen with increased use of immune checkpoint inhibitors (ICIs), and their role in the treatment of early-stage NSCLC is a subject of active investigation. Mounting evidence from preclinical and clinical trials involving immunotherapy for NSCLC has demonstrated the importance of understanding the tumor microenvironment (TME) and the host anti-tumor response. Incorporation of radiation, specifically in hypofractionated regimens, may potentiate the anti-tumor response stimulated by ICIs and thereby improve the efficacy of immunotherapy for these patients. Additional studies are in progress to determine the optimal sequence, dose, fractionation, and duration of combination therapy.
Supplementary Figure 1 from Validation of Biomarkers That Complement CA19.9 in Detecting Early Pancreatic Cancer (2023)

&lt;p&gt;Supplementary Figure 1. Scatter plots of AGR2, SYCN and REG1B in the training and validation cohorts. AGR2 (A,B), REG1B (C,D) and SYCN (E,F) for training and validation cohorts respectively. Black horizontal lines represent the medians. PDAC=pancreatic ductal adenocarcinoma.&lt;/p&gt;
Microparticules : de la génération de plasmine à la standardisation d'un biomarqueur émergeant (2010)

Les microparticules (MP) sont des vesicules qui resultent du bourgeonnement des membranesdes cellules activees ou apoptotiques. Leur capacite a vectoriser des systemes fonctionnelsexprimes par leurs cellules d’origine nous a conduit a explorer, la generation de plasmine aleur surface. Dans un premier travail, nous montrons que les MP derivees de cellulesendotheliales (MPE) sont des surfaces catalytiques capables d’activer le plasminogene par lesysteme de l’urokinase et de son recepteur (uPA/uPAR). Les MPE agissent comme desvecteurs de plasmine constituant une nouvelle voie dans la regulation des activitesproteolytiques de l’endothelium. Dans un second travail, nous avons montre que l’uPA porteepar les cellules ou par les MPE est specifiquement impliquee dans un mecanismereconnaissance du plasminogene lie a une autre surface biologique generant de la plasmine insitu avec une grande efficacite. Dans un troisieme travail, nous montrons que cette activitefibrinolytique est detectable sur les MP extraites de la circulation sanguine, ou elle est plusspecifiquement portee par les sous populations endotheliales et leucocytaires. Cette activitequi est dependante de l’uPA mais aussi de l’activateur tissulaire du plasminogene, estmodulee dans des pathologies cardiovasculaires et auto-immunes. Dans une seconde partie, lapertinence de la mesure des MP comme biomarqueur en pratique clinique nous a amene anous focaliser sur leurs methodes d’analyse. En effet, a l’heure actuelle, l’evaluation dubenefice apporte par les MP est limitee par un manque de standardisation des methodologies.Dans ce travail, nous presentons une nouvelle strategie de standardisation de la cytometrie enflux (CMF) et son evaluation dans le cadre d’une etude multicentrique utilisant des microbillesfluorescentes calibrees en taille. Enfin, nous discutons dans une revue les limitesactuelles de la CMF et les strategies ou ameliorations technologiques permettant de lesdepasser.
Pseudomonas aeruginosa ExoS Induces Intrinsic Apoptosis in Target Host Cells in a Manner That is Dependent on its GAP Domain Activity (2018)

Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen that causes serious infections in immunocompromised individuals and cystic fibrosis patients. ExoS and ExoT are two homologous bifunctional Type III Secretion System (T3SS) virulence factors that induce apoptosis in target host cells. They possess a GTPase Activating Protein (GAP) domain at their N-termini, which share ~76% homology, and an ADP-ribosyltransferase (ADPRT) domain at their C-termini, which target non-overlapping substrates. Both the GAP and the ADPRT domains contribute to ExoT's cytotoxicity in target epithelial cells, whereas, ExoS-induced apoptosis is reported to be primarily due to its ADPRT domain. In this report, we demonstrate that ExoS/GAP domain is both necessary and sufficient to induce mitochondrial apoptosis. Our data demonstrate that intoxication with ExoS/GAP domain leads to enrichment of Bax and Bim into the mitochondrial outer-membrane, disruption of mitochondrial membrane and release of and cytochrome c into the cytosol, which activates initiator caspase-9 and effector caspase-3, that executes cellular death. We posit that the contribution of the GAP domain in ExoS-induced apoptosis was overlooked in prior studies due to its slower kinetics of cytotoxicity as compared to ADPRT. Our data clarify the field and reveal a novel virulence function for ExoS/GAP as an inducer of apoptosis.
Abstract 1902: Comparison of 256×0.5mm and 64×0.5mm Multidetector Computed Tomography Image Quality and Accuracy in a Custom-Designed, Motion-Simulating Phantom of Coronary Artery Stenosis (2007)

There is a high incidence of SLIL, LTIL, and TFC articular disc disruptions in the cadaveric model. Large ligament and TFC articular disc disruptions without wrist arthrosis are very common.
Revisiting epidemic network evolution with a new representation (2016)

This study revisits the test problem of evolving a network that gives the contact structure of a population so as to maximize the length of epidemics based on the network. A novel feature of the study is to use a new representation for network evolution. The representation consists of a sequence of editing commands that modify a starting network to specify a final network evaluated for its epidemic properties. The representation is parametrized by specifying the probability each editing command will be generated in initial populations and during mutation. The original work on long-epidemic networks required a sophisticated type of evolutionary algorithm, the restarting-recentering evolutionary algorithm, to obtain high-fitness results. Use of the new representation permits superior results and obtains them using a simpler type of evolutionary algorithm. A second novel result is the introduction of a new type of tournament selection, useful for at least some types of evolution that use stochastic fitness functions.
Waveguide resonators and filters (2000)

The purpose of this paper is to investigate a novel class of waveguide resonator structures using periodic metal septa for use at microwave, mm-wave, submm-wave and terahertz frequencies. Its aim is to show that this type of resonator can be easily realized with a single metal insert within circular, ridged and rectangular waveguide. One type of resonator which used quarter-wavelength metallic septa was employed. The simulated results for air-filled metal pipe rectangular and ridged waveguide resonator and filter structures using periodic metallic septa are presented. (3 pages)
Induced pluripotent stem cells derived from a patient with autosomal dominant familial neurohypophyseal diabetes insipidus caused by a variant in the AVP gene (2016)

Autosomal dominant familial neurohypophyseal diabetes insipidus (adFNDI) is caused by variants in the arginine vasopressin (AVP) gene. Here we report the generation of induced pluripotent stem cells (iPSCs) from a 42-year-old man carrying an adFNDI causing variant in exon 1 of the AVP gene using lentivirus-mediated nuclear reprogramming. The iPSCs carried the expected variant in the AVP gene. Furthermore, the iPSCs expressed pluripotency markers; displayed in vitro differentiation potential to the three germ layers and had a normal karyotype consistent with the original fibroblasts. This iPSC line is useful in future studies focusing on the pathogenesis of adFNDI.
Effect of Traverse Speed Variation on Microstructural Properties and Corrosion Behavior of Friction Stir Welded WE43 Mg Alloy Joints (2023)

The growing demand for Magnesium in the automotive and aviation industries has enticed the need to improve its corrosive properties. In this study, the WE43 magnesium alloys were friction stir welded (FSW) by varying the traverse speed. FSW eliminates defects such as liquefication cracking, expulsion, and voids in joints encountered frequently in fusion welding of magnesium alloys. The microstructural properties were scrutinized using light microscopy (LM) and scanning electron microscopy (SEM). Additionally, the elemental makeup of precipitates was studied using electron dispersive X-ray spectroscopy (EDS). The electrochemical behavior of specimens was evaluated by employing potentiodynamic polarization tests and was correlated with the microstructural properties. A defect-free weldment was obtained at a traverse and rotational speed of 100 mm/min and 710 rpm, respectively. All weldments significantly improved corrosion resistance compared to the base alloy. Moreover, a highly refined microstructure with redistribution/dissolution of precipitates was obtained. The grain size was reduced from 256 µm to around 13 µm. The corrosion resistance of the welded sample was enhanced by 22 times as compared to the base alloy. Hence, the reduction in grain size and the dissolution/distribution of secondary-phase particles within the Mg matrix are the primary factors for the enhancement of anti-corrosion properties.
Acceleration of a Feature Selection Algorithm Using High Performance Computing (2020)

Feature selection is a subfield of data analysis that is on reducing the dimensionality of datasets, so that subsequent analyses over them can be performed in affordable execution times while keeping the same results. Joint Mutual Information (JMI) is a highly used feature selection method that removes irrelevant and redundant characteristics. Nevertheless, it has high computational complexity. In this work, we present a multithreaded MPI parallel implementation of JMI to accelerate its execution on distributed memory systems, reaching speedups of up to 198.60 when running on 256 cores, and allowing for the analysis of very large datasets that do not fit in the main memory of a single node.
Efficient and Reliable Lock-Free Memory Reclamation Based on Reference Counting (2008)

We present an efficient and practical lock-free method for semiautomatic (application-guided) memory reclamation based on reference counting, aimed for use with arbitrary lock-free dynamic data structures. The method guarantees the safety of local as well as global references, supports arbitrary memory reuse, uses atomic primitives that are available in modern computer systems, and provides an upper bound on the amount of memory waiting to be reclaimed. To the best of our knowledge, this is the first lock-free method that provides all of these properties. We provide analytical and experimental study of the method. The experiments conducted have shown that the method can also provide significant performance improvements for lock-free algorithms of dynamic data structures that require strong memory management.
Feasibility of Assessing Liver Lipid by Proton Magnetic Resonance Spectroscopy in Healthy Normal and Overweight Prepubertal Children (2010)

These preliminary data suggest that (1)H-MRS obtained in a standard pediatric clinical environment may be used to determine IHL in healthy normal and overweight prepubertal youth. This noninvasive technique may prove useful in identifying early markers of the metabolic syndrome in at-risk youth.
A HOLISTIC MULTI-METHODOLOGY FOR SUSTAINABLE RENOVATION (2018)

A review of the barriers for building renovation has revealed a lack of methodologies, which can promote sustainability objectives and assist various stakeholders during the design stage of building renovation/retrofitting projects. The purpose of this paper is to develop a Holistic Multi-methodology for Sustainable Renovation, which aims to deal with complexity of renovation projects. It provides a framework through which to involve the different stakeholders in the design process to improve group learning and group decision-making, and hence make the building renovation design process more robust and efficient. Therefore, the paper discusses the essence of multifaceted barriers in building renovation regarding cultural changes and technological/physical changes. The outcome is a proposal for a multi-methodology framework, which is developed by introducing, evaluating and mixing methods from Soft Systems Methodologies (SSM) with Multiple Criteria Decision Making (MCDM). The potential of applying the proposed methodology in renovation projects is demonstrated through a case study.
Electrochemical investigation and capacitance properties of a novel electrodeposited ordered mesoporous cobalt hydroxide films (2012)

The present work explored a novel, simple and low cost electrochemical route for the investigation of ordered mesoporous cobalt hydroxide films electrodeposited onto gold substrate from cobalt acetate in pluronic lyotropic liquid crystal (P84). This method produces thin films of cobalt hyhdroxid mesostructures on gold substrate by combination of potentiostatic and voltammetric electrodeposition techniques. The prepared nanomaterials were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM) and x-ray diffraction (XRD). Electrochemical capacitance properties of cobalt hydroxide films were evaluated via cyclic voltammetry method. The film showed maximum specific capacitance of 727 F/g in 1 M sodium hydroxide electrolyte at scan rate of 5 mV/s. This indicates the potential application of cobalt films in electrochemical supercapacitors.

	 

	Key words: Electrodeposition, mesostructures, electrochemical measurements, specific capacitance, supercapacitors.
CHAUSSEES 1977 - METHODES ET EXPERIENCES FRANCAISES POUR LA CREATION DE CARACTERISTIQUES ANTIDERAPANTES, ELEVEES A LA CONSTRUCTION DE REVETEMENTS EN BETON (1977)

COMMUNICATION PRESENTEE AU COLLOQUIUM ON SURFACE CHARACTERISTICS OF CONCRETE PAVEMENTS, LONDRES, SEPTEMBRE 1977. L'AUTEUR PASSE BRIEVEMENT EN REVUE LES PROCEDES EMPLOYES JUSQU'A MAINTENANT EN FRANCE ET A L'ETRANGER POUR DONNER AUX COUCHES DE ROULEMENT DES CARACTERISTIQUES ANTIDERAPANTES CONVENABLES EN TRAITANT LE BETON IMMEDIATEMENT APRES MISE EN OEUVRE. LES PROCEDES BRITANNIQUES, FRANCAIS ET BELGE EN COURS DE RECHERCHE OU DEVELOPPEMENT SONT DECRITS ET LEUR COMPORTEMENT SOUS TRAFIC EST ANALYSE. UNE ETUDE SUCCINCTE CONSTITUANT L'EBAUCHE D'UN PROJET DE RECHERCHE SUR L'INFLUENCE DES CONSTITUANTS DU MORTIER SUR LA REGENERATION DE LA MICRORUGOSITE EST DONNEE ET COMMENTEE. L'AUTEUR CONCLUT QUE : - LA MACRORUGOSITE DE LA COUCHE DE ROULEMENT NE PEUT PAS APPARAITRE OU ETRE MAINTENUE PAR L'USURE DIFFERENTIELLE ENTRE LE MORTIER ET LES GRANULATS MOYENS ET GROS MEME S'ILS SONT TRES DURS. LA MACRORUGOSITE DOIT DONC ETRE CREEE PAR TRAITEMENT DU BETON FRAIS SANS REDUIRE LA RESISTANCE A L'USURE DE LA SURFACE. - LA MICRORUGOSITE DEVRAIT DURER SI L'USURE EST EXTREMEMENT BASSE (CAS DE GRANULATS POUR GRAVILLONS ENROBES QUI DOIVENT AVOIR UN CPA ELEVE ET UN LOS ANGELES BAS) OU SE REGENERER SI L'USURE EST BASSE (CAS DES MORTIERS DE BETON ROUTIER).
PLASMA EXPANDERS (1952)

There is no substitute for blood. Medical officers in World War II who had sufficient amounts of blood and plasma available used four times as much blood as plasma in patients with a deficiency of blood volume. At present, there is no substance available that can assume the many functions that a good preparation of whole blood is now known to have. Interest in substances that act as poor substitutes for blood or as satisfactory substitutes for plasma occurs periodically during times of impending national emergency. The problem of whole blood and plasma logistics for our military forces as well as for our civilian population will be an extremely difficult one in the event major atomic disasters occur as a part of war. Our hope for preventing and combating shock in the great multitude of casualties that will inevitably follow such a disaster lies in plasma expanders, which are capable
[Medical therapy for menstrual migraine]. (1996)

A menstrual migraine occurs in approximately 7-10 % of women suffering from migraine. The migraine occurs from 2 days before until 3 days after the end of the menstrual period. The choice of treatment depends on the duration of the attack, which ranges from 3 to 7 days. An attack of up to 3 days duration should be treated with acetylsalicylic acid, ergotamine tartrate or naproxen, each in combination with an antiemetic (domperidone, metoclopramide). If there is no response, sumatriptan can be administered orally (25-100 mg) or subcutaneously (6 mg). In the attacks continue for more than 3 days, short-term prophylaxis with naproxen or the application of an estrogen-containing patch is indicated. Neither ovulation inhibitors nor traditional migraine prophylaxis has an influence on menstrual migraine. Patients should keep a headache diary. Short-term prophylaxis with ergotamine tartrate or tamoxifen is obsolete.
Endogenous Histamine in Cultured Bovine Adrenal Chromaffin Cells (1993)

Histamine releases catecholamines and opioids in primary cultured bovine adrenal medullary (BAM) chromaffin cells. We have studied whether histamine is synthesized and localized in BAM cells, and whether it can be released upon activation with secretagogues. In BAM cells histamine is immunohistochemically co-localized with tyrosine hydroxylase in 45 +/- 8% of all cells. Only histamine immunoreactivity was observed in 8 +/- 2% of all BAM cells. No mast-cell-like cells were observed in our system. Histamine can be released from BAM cells by high potassium (56 mM K+) in a calcium-dependent manner. Compound 48/80 did not release histamine from BAM cells but nicotine caused a dose-dependent liberation of the amine. Cultured BAM cells have histidine decarboxylase activity which is inhibited by alpha-fluoromethylhistidine. These results indicate that endogenous histamine is synthesized, stored and released in BAM chromaffin cells in vitro.
Mechanism of Hydrocracking. Reactions of Paraffins and Olefins (1964)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMechanism of Hydrocracking. Reactions of Paraffins and OlefinsH. L. Coonradt and W. E. GarwoodCite this: Ind. Eng. Chem. Process Des. Dev. 1964, 3, 1, 38–45Publication Date (Print):January 1, 1964Publication History Published online1 May 2002Published inissue 1 January 1964https://pubs.acs.org/doi/10.1021/i260009a010https://doi.org/10.1021/i260009a010research-articleACS PublicationsRequest reuse permissionsArticle Views3000Altmetric-Citations224LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
A 900-MHz Direct Delta-Sigma Receiver in 65-nm CMOS (2010)

Direct delta-sigma receiver architecture is introduced for wireless communication systems, such as LTE or WiMax. Architecture is based on direct downconversion, delta-sigma feedback that is up-converted to RF, and N-path filtering technique. Hence, the core receiver functions including channel selection filtering are embedded to a RF ADC with excellent linearity performance. This is achieved by transforming narrow-band filtering partially to RF injecting feedback into the input of the second amplifier stage, hence relieving requirements of the most critical subsequent stages. A 900-MHz direct delta-sigma receiver prototype occupies an active area of 1.2 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> in 65-nm CMOS. The receiver for low-band cellular operations achieves NF of 2.3 and 6.2 dB in conventional and delta-sigma modes, respectively, and out-of-band IIP3 up to +4 dBm when the delta-sigma loop is active. The chip consumes 80 mW from a 1.2-V supply.
Negative Regulation by HLA-DO of MHC Class II-Restricted Antigen Processing (1997)

HLA-DM is a major histocompatibility complex (MHC) class II-like molecule that facilitates antigen processing by catalyzing the exchange of invariant chain-derived peptides (CLIP) from class II molecules for antigenic peptides. HLA-DO is a second class II-like molecule that physically associates with HLA-DM in B cells. HLA-DO was shown to block HLA-DM function. Purified HLA-DM-DO complexes could not promote peptide exchange in vitro. Expression of HLA-DO in a class II+ and DM+, DO- human T cell line caused the accumulation of class II-CLIP complexes, indicating that HLA-DO blocked DM function in vivo and suggesting that HLA-DO is an important modulator of class II-restricted antigen processing.
Numerical Investigation of Various geometries of Steam cracking furnace tubes for reduced fouling rate (2019)

International audience
Kirk-Othmer concise encyclopedia of chemical technology (1999)

An authoritative l300-page condensation of the Third Edition of the Kirk-Othmer Encyclopedia of Chemical Technology (25 volumes plus supplement volume). Approximately 1,100 articles were abridged and condensed from the original and reviewed by the author and other experts for accuracy. Cross references, index, extensive tables, charts, and general references.