gebhart/patrepeval huggingface dataset:
Enabling pervasive mobile applications with the FM radio broadcast data system (2010)

Many existing electronic devices lack data connectivity but carry an FM radio receiver. Such devices include media players, vehicular audio systems, low-end mobile phones, and mobile phones whose owners cannot afford data plans. We observe that the highly available FM radio data system (RDS) provides a low-rate digital broadcast channel that is specific to the radio station an FM receiver tunes to. While RDS is mainly intended for delivering simple information about the station and current program, we argue that it can be employed to enable a broad range of new applications and enhance existing ones. In this position paper, we discuss a number of applications that can be enabled or enhanced by RDS, and analyze the challenges evolved. We then present RDS-Link, a protocol to efficiently transfer broadcast data over RDS, and characterize its performance under real-life settings.
Paramagnetic metal and oxygen species observed with Rh/γ-Al2O3 and Rh/ZrO2. Dependence on the decarbonylation temperature of [Rh4(CO)12] on alumina and zirconia supports (1986)

Paramagnetic metal and oxygen species observed when alumina-(or zirconia-supported rhodium, Rh/γ-Al2O3(ZrO2), is obtained by the decarbonylation of [Rh4(CO)12]-Al2O3(ZrO2) are discussed as a function of the decarbonylation temperature (250–600 °C) and the method of decarbonylation (pyrolysis in vacuo or reduction in an H2 stream). On vacuum-pyrolysed samples, RhP(T)/γ-Al2O3, RhII formal centres are stable only after decarbonylation at 250 °C; contact with O2 produces [RhIIIn–O2]˙–(n= 1,2) and Al3+—O2–, with an increasing amount of Al3+—O–2 as the decarbonylation temperature increases. RhP(T)/ZrO2 does not show paramagnetic species before contact with O2: the treatment with O2 stabilizes both [Rh2III—O2]˙– and Zr4+—O–2 centres at a decarbonylation temperature of 250 °C, while essentially Zr4+—O2– alone is formed at higher temperature. On H2 reduced samples, RhH(T)/γ-Al2O3, formal RhO centres formed in the decarbonylation temperature range 250–500 °C, while no paramagnetic species were observed on RhH(T)/ZrO2. Contact with O2 shows behaviour of RhH(T)/γ-Al2O3(ZrO2) very similar to that of RhP(T)/γ-Al2O3(ZrO2). The stability of the Rh—O2 bond is a function of the metal positive charge and it is related to the decarbonylation temperature. The strength of the interaction between O2– and the support acidic centres, Al3+ and Zr4+, is always high in γ-Al2O3-supported samples, and dramatically increases in ZrO2-supported samples on increasing the decarbonylation temperature. Different pathways of electron transfer can explain the observed behaviour of Rh/ZrO2.
Reference and Interpretive Ranges for α1-Antitrypsin Quantitation by Phenotype in Adult and Pediatric Populations (2012)

Laboratory evaluation of α(1)-antitrypsin (A1AT) deficiency involves measurement of circulating A1AT protein (quantitation) and characterization of A1AT genetic polymorphisms (phenotyping or genotyping). This study compared adult and pediatric A1AT reference ranges in patients with nondeficiency alleles and examined A1AT concentrations in multiple other phenotypes. A1AT phenotype and quantitation were retrospectively collected on adult (n = 21,444) and pediatric (n = 2,469) samples that were submitted for laboratory evaluation of A1AT deficiency. The 95% reference ranges for normal adult and pediatric populations with the M/M phenotype were determined to be 100 to 273 mg/dL (18.4-50.2 μmol/L) and 93 to 251 mg/dL (17.1-46.2 μmol/L), respectively (P < .0001). Decreased concentrations of A1AT correlated with heterozygosity and homozygosity for the S and Z alleles in both the adult and pediatric groups. Other rare alleles, such as I, were also associated with decreased concentrations of A1AT, particularly in the context of a Z allele, and may warrant monitoring for symptoms of deficiency.
1H-NMR: A New Detector for liquid Chromatography (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT1H-NMR: A New Detector for liquid ChromatographyH. C. DornCite this: Anal. Chem. 1984, 56, 6, 747A–758APublication Date (Print):May 1, 1984Publication History Published online29 May 2012Published inissue 1 May 1984https://pubs.acs.org/doi/10.1021/ac00270a798https://doi.org/10.1021/ac00270a798research-articleACS PublicationsRequest reuse permissionsArticle Views151Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Cooperation of GBP and LVQ networks for optical character recognition (2003)

One way to solve the real-world optical character recognition (OCR) problems is described. The strategy chosen was to introduce a neural character recognition box into a classical OCR product. The authors recall the different steps involved in the OCR process. Some of the problems arising in the design of a database for the training of neural networks on OCR and recognition are discussed. They tested several multilayer perceptron architectures, using strong constraints and shared weights, and showed that the cooperation between the generalised backpropagation (GBP) and LVQ algorithms resulted in better performance on real-world databases than classical techniques. The speedup of the total recognition process is considered.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Extension and application of the “enzyme test bench” for oxygen consuming enzyme reactions (2013)

Within industrial process development, powerful screening techniques are required to select the optimal biocatalyst regarding such process characteristics as cost effectiveness, turnover number or space time yield. Conventional measurement of the initial enzyme activity, which is the established high throughput screening technique, disregards the long-term stability of an enzyme. A new model based technique called "enzyme test bench" was recently presented before by our group which addresses this issue. It combines the high throughput screening approach with an extensive enzyme characterization, focusing especially on the long-term stability. The technique is based on modeling enzyme activation and deactivation as temperature dependent reactions in accordance with the Arrhenius law. Controlling these reactions by tailor made temperature profiles, the slow long-term deactivation effects are accelerated and characterizing models are parameterized. Thus, the process properties of an enzyme can be predicted and included into the screening procedure. Moreover, the optimum process temperature as function of the envisaged operation time can be found by these means. In this work, the technique is extended to the important class of oxygen consuming reactions. For this aim, a suitable assay and a defined oxygen supply were established. This extended technique was applied to characterize and to optimize a complex, multi-stage laccase-mediator system (LMS). For the variation and optimization of the enzyme to mediator to substrate ratio, experiments in microtiter plates were performed. Predictions from this high throughput characterization were compared to long-term experiments in a RAMOS device (Respiration Activity Monitoring System), a technique for on-line monitoring of the oxygen transfer rate in shake flasks. Within the limits of the model validity, the enzyme test bench predictions are in good agreement with the long-term experiments.
Increased mRNA expression of the B1 and B2 bradykinin receptors and antinociceptive effects of their antagonists in an animal model of neuropathic pain (2000)

We examined the role of B1 and B2 bradykinin receptors in promoting neuropathic hypersensitivity following peripheral nerve injury. Forty eight-hours following chronic constriction injury to a rat sciatic nerve there was an increased expression of B2 receptor mRNA in the lumbar dorsal root ganglia ipsilateral to the site of nerve injury. At 14 days following surgery there was also an ipsilateral increase of B1 receptor mRNA as well as a contralateral increased expression of B2 receptor mRNA. Increased expression of both receptors also coincided with analgesic effects of their antagonists. While HOE-140, a potent B2 receptor antagonist was analgesic at both time points tested, the B1 receptor antagonist des-Arg9, [Leu8]-BK had an analgesic effect only at 14 days. The results support the concept that peripheral nerve injury is associated with local inflammation and that bradykinin, acting on both of its receptors promotes pain hypersensitivity.
Author response: Spatial alanine metabolism determines local growth dynamics of Escherichia coli colonies (2021)

An investigation of spatiotemporal metabolic differentiation during colony biofilm growth of E. coli revealed that alanine is cross-fed between spatially segregated subpopulations within the colony, to support cellular growth in an otherwise nutrient-deprived region of the colony.
Abstract 16997: Polymorphic Ventricular Tachycardia: Torsade De Pointes or Purkinje Fiber Triggered Polymorphic Ventricular Tachycardia? (2018)

Introduction: Purkinje Fiber triggered polymorphic ventricular tachycardia (Purkinje VT) is often misidentified as torsade de pointes ventricular tachycardia (TdP), While TdP is almost always responsive to IV magnesium, correcting electrolytes and removing offending QT prolonging drugs, Purkinje VT is not amenable to this treatment, is usually refractory to anti-arrhythmic drug treatment and is best managed by ablation of Purkinje fiber triggers. Methods: We compared the clinical and electrocardiographic features of Purkinje VT to TdP to determine distinguishing features. Results: Since June 2015, we identified 11 patients (pts) with Purkinje VT and compared them to 11 patients with TdP. Ten of the 11 Purkinje VT pts were male vs 1 of 11 TdP pts (p &lt; 0.005). The LVEF was 22.4 ± 7.2 % in the Purkinje VT pts vs.39.8 ±10.4 % in the TdP pts (p &lt;0.005). Both the QTc (0.46 ± 0.05 vs. 0.62 ± 0.09 sec) and the coupling interval from the last normal complex to the first VT complex (0.35 ± 0.06 vs. 0.53 ± 0.08 sec) were shorter in the Purkinje VT pts than in the TdP pts (p &lt;0.0001 for both). Although the QTc was significantly longer in the TdP pts, 4 of the 11 Purkinje VT patients had QTc intervals ≥ 500 msec. All the Purkinje VT pts had frequent PVCs triggering the PMVT vs 5 of 11 pts with TdP who had PVC of the same morphology as the first complex of torsade preceding the TdP (p &lt;0.05). Patients with Purkinje VT were more likely to be in cardiogenic shock (6 of 11 vs 0 of 11) and to present with VT storm (7 of 11 vs 1 of 11) than pts with TdP (p &lt;0.05 for both). In addition, Pts with Purkinje VT were more likely to have associated episodes of rapid monomorphic VT (9 of 11 vs 2 of 11) than those with TdP (p &lt;0.01) Conclusions: Purkinje VT is distinguished from TdP by a short coupling interval, a relatively shorter QTc and the obligatory presence of triggering. PVCs. Pts with Purkinje VT are more likely to present with VT storm, cardiogenic shock and to have associated episodes of monomorphic VT/VFlutter than pts with TdP.
Covid-19 automated diagnosis and risk assessment through Metabolomics and Machine-Learning (2020)

ABSTRACT COVID-19 is still placing a heavy health and financial burden worldwide. Impairments in patient screening and risk management play a fundamental role on how governments and authorities are directing resources, planning reopening, as well as sanitary countermeasures, especially in regions where poverty is a major component in the equation. An efficient diagnostic method must be highly accurate, while having a cost-effective profile. We combined a machine learning-based algorithm with instrumental analysis using mass spectrometry to create an expeditious platform that discriminate COVID-19 in plasma samples within minutes, while also providing tools for risk assessment, to assist healthcare professionals in patient management and decision-making. A cross-sectional study with 728 patients (369 confirmed COVID-19 and 359 controls) was enrolled from three Brazilian epicentres (São Paulo capital, São Paulo countryside and Manaus) in the months of April, May, June and July 2020. We were able to elect and identify 21 molecules that are related to the disease’s pathophysiology and 26 features to patient’s health-related outcomes. With specificity &gt;97% and sensitivity &gt;83% from blinded data, this screening approach is understood as a tool with great potential for real-world application.
A nanobody-based fluorescent reporter reveals human α-synuclein in the cell cytosol (2020)

Aggregation and spreading of α-Synuclein (αSyn) are hallmarks of several neurodegenerative diseases, thus monitoring human αSyn (hαSyn) in animal models or cell cultures is vital for the field. However, the detection of native hαSyn in such systems is challenging. We show that the nanobody NbSyn87, previously-described to bind hαSyn, also shows cross-reactivity for the proteasomal subunit Rpn10. As such, when the NbSyn87 is expressed in the absence of hαSyn, it is continuously degraded by the proteasome, while it is stabilized when it binds to hαSyn. Here, we exploit this feature to design a new Fluorescent Reporter for hαSyn (FluoReSyn) by fusing NbSyn87 to fluorescent proteins, which results in fluorescence signal fluctuations depending on the presence and amounts of intracellular hαSyn. We characterize this biosensor in cells and tissues to finally reveal the presence of transmittable αSyn in human cerebrospinal fluid, demonstrating the potential of FluoReSyn for clinical research and diagnostics.
Targeting DNA Repair Proteins: A Promising Avenue for Cancer Gene Therapy (2006)

Enhanced DNA repair in many cancer cells can be correlated to the resistance to cancer treatment, and thus contributes to a poor prognosis. Ionizing radiation and many anti-cancer drugs induce DNA double-strand breaks (DSBs), which are usually regarded as the most toxic types of DNA damages. Repair of DNA DSBs is vital for maintaining genomic stability and hence crucial for survival and propagation of all cellular organisms. Therefore, reducing the capacity of cancer cells to repair DSBs could sensitize tumors to radio/chemotherapy. Many investigators have used gene therapy strategies to down-regulate or inactivate proteins involved in the repair of DSBs in order to reduce the survival of cancer cells. Herein, are reviewed several protein candidates that have been targeted by different gene therapy approaches. Results obtained from in vitro and in vivo experiments are presented and discussed in the perspective of potential gene therapy clinical trials.
Detecting energy-greedy anomalies and mobile malware variants (2008)

Mobile users of computation and communication services have been rapidly adopting battery-powered mobile handhelds, such as PocketPCs and SmartPhones, for their work. However, the limited battery-lifetime of these devices restricts their portability and applicability, and this weakness can be exacerbated by mobile malware targeting depletion of battery energy. Such malware are usually difficult to detect and prevent, and frequent outbreaks of new malware variants also reduce the effectiveness of commonly-seen signature-based detection. To alleviate these problems, we propose a power-aware malware-detection framework that monitors, detects, and analyzes previously unknown energy-depletion threats. The framework is composed of (1) a power monitor which collects power samples and builds a power consumption history from the collected samples, and (2) a data analyzer which generates a power signature from the constructed history. To generate a power signature, simple and effective noise-filtering and data-compression are applied, thus reducing the detection overhead. Similarities between power signatures are measured by the χ2-distance, reducing both false-positive and false-negative detection rates. According to our experimental results on an HP iPAQ running a Windows Mobile OS, the proposed framework achieves significant (up to 95%) storage-savings without losing the detection accuracy, and a 99% true-positive rate in classifying mobile malware.
Combined Hapto-Visual and Auditory Rendering of Cultural Heritage\n Objects (2020)

In this work, we develop a multi-modal rendering framework comprising of\nhapto-visual and auditory data. The prime focus is to haptically render point\ncloud data representing virtual 3-D models of cultural significance and also to\nhandle their affine transformations. Cultural heritage objects could\npotentially be very large and one may be required to render the object at\nvarious scales of details. Further, surface effects such as texture and\nfriction are incorporated in order to provide a realistic haptic perception to\nthe users. Moreover, the proposed framework includes an appropriate sound\nsynthesis to bring out the acoustic properties of the object. It also includes\na graphical user interface with varied options such as choosing the desired\norientation of 3-D objects and selecting the desired level of spatial\nresolution adaptively at runtime. A fast, point proxy-based haptic rendering\ntechnique is proposed with proxy update loop running 100 times faster than the\nrequired haptic update frequency of 1 kHz. The surface properties are\nintegrated in the system by applying a bilateral filter on the depth data of\nthe virtual 3-D models. Position dependent sound synthesis is incorporated with\nthe incorporation of appropriate audio clips.\n
A bi-axial vacuum-packaged piezoelectric MEMS mirror for smart headlights (2020)

This paper presents a 2D MEMS mirror for smart headlights, combing high-Q vacuum package with AR (Anti Reflecting)-coating, piezoelectric driving and Lissajous scanning. While the vacuum package protects the MEMS device and the AR-coating suppresses parasite reflections from the glass lid, the AlN-based piezoelectric actuators are robust against shock and vibration in harsh environment, comparing to fragile capacitive finger structures. This gimbal-less MEMS mirror with a large circular aperture (diameter = 5.5 mm) utilizes Lissajous scanning possessing two perpendicular torsion modes with frequencies of f<sub>x</sub> = 2.26 kHz, f<sub>y</sub> = 2.30 kHz fulfilling high light density and large total optical scanning angles of 55°, 30° at ± 40 V<sub>AC</sub>. A 2D projection of 50° x 20° was realized, where the angle loss comparing to the 1D testing arose from pincushion distortion, whose effect was severely reduced by the redesign run. Due to the great long-term stability of AlN and protection of vacuum packages, the MEMS mirror also shows a good reliability. This paper will describe and discuss the design, fabrication and characterization results of this MEMS mirror.
Magnetic and conductive graphene papers toward thin layers of effective electromagnetic shielding (2014)

We demonstrate a simple approach for fabricating novel free-standing magnetic and conductive graphene hybrid papers that present great potential as thin layers with effective shielding performance.
Plasma surface modification of polymers (1980)

Thin plasma polymerization films are discussed from the viewpoint of simplicity in production stages. The application of selective, absorbent films and films used in selective permeability was tested. The types of surface modification of polymers discussed are: (1) plasma etching, (2) surface coating by plasma polymerized thin films, and (3) plasma activation surface graft polymerization.
Measurement of interface potential change and space charge region across metal/organic/metal structures using Kelvin probe force microscopy (2004)

We report on high-resolution potential measurements across complete metal/organic molecular semiconductor/metal structures using Kelvin probe force microscopy in inert atmosphere. It is found that the potential distribution at the metal/organic interfaces is in agreement with an interfacial abrupt potential changes and the work function of the different metals. The potential distribution across the organic layer strongly depends on its purification. In pure Alq3 the potential profile is flat, while in nonpurified layers there is substantial potential bending probably due to the presence of deep traps. The effect of the measuring tip is calculated and discussed.
Developing a Half-Cladding Semiconductor Photonic Device Structure for Surface Transmission of Light Waves (2011)

A control of the light-wave properties is critical issue in developing attractive photonic devices. In conventional photonic devices such as semiconductor waveguide light sources, complicated techniques were required to fabricate the high-aspect-ratio artificial periodic structures that help controlling the light-wave properties. This is because the conventional photonic devices are constructed with thick cladding layers for an optical confinement. In this paper, we propose and fabricate a half-cladding semiconductor light source as an attractive photonic device structure. We successfully demonstrated a light emission from the light source under current injection at room temperature. With a half-cladding structure, the total thickness between the device surface and the top of the active layer is on the sub-µm scale. Controlling the light-wave properties should therefore be possible with artificial surface microstructures fabricated by a low aspect ratio process sequence.
Accurate Position Control for Hydraulic Servomechanisms (2019)

Accurate Position Control for Hydraulic Servomechanisms Manuel Pencelli, Renzo Villa, Alfredo Argiolas, Gianni Ferretti, Marta Niccolini, Matteo Ragaglia, Paolo Rocco and Andrea Maria Zanchettin Pages 250-257 (2019 Proceedings of the 36th ISARC, Banff, Canada, ISBN 978-952-69524-0-6, ISSN 2413-5844) Abstract: A common problem when operating heavy hydraulic machines consists in the inability of performing accurate motion. In the last few years the development of non-linear control techniques and the production of increasingly more accurate and cheaper hydraulic drives induced a steadily growing interest towards the development of controlled hydraulic systems. Clearly, this interest is also motivated by the possibility to exploit the huge power density, which is an intrinsic feature of hydraulic systems. This paper specifically focuses on the development of several position control schemes, whose aim is to guarantee accurate motion of a standalone hydraulic servomechanism. By relying on an experimentally validated mathematical model of the servomechanism itself, different control schemes have been synthesized and the resulting control performances have been verified and compared together. Keywords: Hydraulic systems, Hydraulic actuators, Motion Control DOI: https://doi.org/10.22260/ISARC2019/0034 Download fulltext Download BibTex Download Endnote (RIS) TeX Import to Mendeley