gebhart/patrepeval huggingface dataset:
Adaptive Autocorrelation Approach for Fingerprint-based Distance Dependent Positioning Algorithms in WLAN Indoor Areas (2011)

This paper addresses the adaptive autocorrelation approach for the fingerprinting-based distance dependent positioning algorithms (DDPAs) in wireless local area network (WLAN) indoor environment. As far as we know, although the DDPAs, like nearest neighbor (NN), K nearest neighbors (KNN) and weighted KNN (WKNN) algorithms, have been widely utilized for the indoor and outdoor location based services (LBS), the guarantee of location accuracy and precision has always been one of the significant compelling problems. Therefore, in response to this challenging task, the expected errors and associated confidence probabilities are mathematically deduced by the assumptions of logarithmic attenuation model and Gaussian distributions of received radio signal strength (RSS) at the receiver. However, because of the non line of sight (NLOS) property, time-varying interference and multipath effect, the measured radio strength varies a lot in the real-world indoor environment. Therefore, in order to fill this gap, a novel adaptive autocorrelation preprocessing approach is utilized to eliminate the singular strength from the original prestored radio map and improve the matching accuracy of DDPAs. Finally, compared with traditional DDPAs without adaptive autocorrelation preprocessing, the feasibility and effectiveness of the adaptive autocorrelation-based DDPAs are verified by approximately decreasing the average errors from 1.13m to 0.75m.
The role of genetics in shellfish restoration (2006)

Restoration of shellfish populations is becoming an increasingly common practice worldwide, as natural fisheries succumb to pressures of overharvesting, habitat loss or degradation, and challenges from invasive competitors and pathogens. Primary genetic concerns relevant to shellfish restoration projects are reviewed, using the cupped oysters Crassostrea gigas and Crassostrea virginica as case studies. Molecular genetic tools can be used to delineate the geographic distribution of germ plasm diversity at the species and intraspecific levels, enabling more informed selection of genetic material for hatchery breeding and production. Maintenance of genetic variability and prevention of excessive inbreeding in hatchery stocks may be facilitated by the use of genetic markers for regular pedigree monitoring. The effect of hatchery supplementation on the effective population size of a recipient wild population (Ryman-Laikre effect) is reviewed in light of the population biology of bivalve molluscs, and appears to be minimal. Deployment of selected enhancement stocks may be a valuable tool for improvement of degraded wild populations, reversing the negative effects of generations of selective harvesting. Molecular genetic tools can be used effectively to monitor restoration programs, when the discriminatory power of the marker(s) is high and high-throughput scoring methods currently available are used.
Intracellular trafficking and endocytosis of CXCR4 in fetal mesenchymal stem/stromal cells (2014)

We conclude that constitutive endocytosis is implicated in the regulation of CXCR4 membrane expression, and suggest a novel pharmacological strategy to enhance migration of systemically-transplanted cells.
Effects of feature type and multiple scanners on brain metastasis stereotactic radiosurgery outcome prediction (2022)

The prediction of brain metastasis (BM) response to stereotactic radiosurgery could assist clinicians when choosing BM treatments. This study investigates the prediction of in-field progression, out-of-field progression, and 1-year overall survival (OS) endpoints using a machine learning classifier. It also investigates the effect of feature type and magnetic resonance imaging (MRI) scanner variability on classifier performance. The study data set consisted of <i>n</i> = 110 BMs across 91 patients for which endpoints, seven clinical features, and MRI scans were available. 635 radiomic features were extracted from the MRI for the BM region-of-interest (ROI) and a 5mm BM ROI dilation. A 1000-iteration bootstrap experimental design was used with a random forest classifier to provide area under the receiver operating characteristic curve (AUC) estimates. This experimental design was used for multiple endpoints, groups of features, and data partitioning by scanner model. In-field progression, out-of-field progression, and 1-year OS were predicted with respective AUC estimates of 0.70, 0.57 and 0.66. For all endpoints, clinical and/or radiomic features from the BM ROI provided optimal performance. MR scanner variability was found to decrease classifier AUC in general, though pre-processing methods were found to counteract this effect for some scanner models. This study shows that in-field progression, out-of-field progression, and 1-year OS can all be predicted to some degree, with in-field progression being predicted most accurately. The effects of scanner variability indicate that more diverse data sets and robust methods to account for scanner variability are required before clinical translation.
Réponse du champignon Alternaria brassicicola à l'effet fongitoxique de la camalexine, principale phytoalexine d'Arabidopsis thaliana. (2009)

Texte non communiqué
Single mode dispersive waves and soliton microcomb dynamics (2017)

Dispersive-wave scattering from dissipative Kerr solitons is induced by spatial-mode interactions within a high-Q micro-resonator. A limiting case, single-mode dispersive waves, are observed and their interaction with the soliton causes hysteretic behavior.
Co-solvent solubilization of some poorly-soluble antidiabetic drugs (2009)

Co-solvent solubilization approach has been used to enhance the solubility of seven antidiabetic drugs: gliclazide, glyburide, glipizide, glimepiride, repaglinide, pioglitazone, and roziglitazone. Solubility in water, phosphate buffer (pH 7.4), six co-solvent solutions prepared in water as well as phosphate buffer (pH 7.4) and pH-solubility profile of various drugs have been determined at 25 degrees C. Aqueous solubility of various drugs was found to be less than 0.04 mg/mL. Solubility of gliclazide, glipizide and repaglinide increased by 3-6 times by using phosphate buffer (pH 7.4) as solvent. Solubility enhancement by pH modification was not sufficient. Significant enhancement in solubility could be achieved by the use of co-solvents. The combined effect of co-solvent and buffer was synergistic and enormous increase in solubility of sulfonylureas and repaglinide could be achieved. In the case of glitazones, however, co-solvent alone caused significant enhancement; the presence of buffer had negative effect on the solubilization potential of the co-solvents. Up to 763, 316, 153, 524, 297, 792 and 513 times increase in solubility could be achieved in the case of gliclazide, glyburide, glimepiride, glipizide, repaglinide, pioglitazone and rosiglitazone, respectively.
Réalisation d'un filtre étroit dans l'infrarouge thermique en technologie nanophotonique. Rapport final. (2017)

National audience
Cover Picture: Hybrid Microstructures from Aligned Carbon Nanotubes and Silica Particles (Small 8‐9/2005) (2005)

The cover picture illustrates new possibilities for integrating nanostructures of different dimensionalities into larger‐scale architectures. The foreground collage shows hybrid microstructures of vertically aligned carbon nanotubes, grown by chemical vapor deposition on close‐packed assemblies of silica microparticles; such an assembly is depicted in the background. For more information, please read the Communication “Hybrid Microstructures from Aligned Carbon Nanotubes and Silica Particles” by G. Ramanath and co‐workers on page 823 ff.
PyNTA: An Open Source Software Application for Live Particle Tracking (2019)

We introduce PyNTA, a modular instrumentation software for live particle tracking. By using the multiprocessing library of Python and the distributed messaging library pyZMQ, PyNTA allows users to acquire images from a camera at close to maximum readout bandwidth while simultaneously performing computations on each image on a separate processing unit. This publisher/subscriber pattern generates a small overhead and leverages the multi-core capabilities of modern computers. We demonstrate capabilities of the PyNTA package on the featured application of nanoparticle tracking analysis. Real-time particle tracking on megapixel images at a rate of 50 Hz is presented. Reliable live tracking reduces the required storage capacity for particle tracking measurements by a factor of approximately 103, as compared with raw data storage, allowing for a virtually unlimited duration of measurements
Effect of Noncanonical Amino Acids on Protein–Carbohydrate Interactions: Structure, Dynamics, and Carbohydrate Affinity of a Lectin Engineered with Fluorinated Tryptophan Analogs (2018)

Protein-carbohydrate interactions play crucial roles in biology. Understanding and modifying these interactions is of major interest for fighting many diseases. We took a synthetic biology approach and incorporated noncanonical amino acids into a bacterial lectin to modulate its interactions with carbohydrates. We focused on tryptophan, which is prevalent in carbohydrate binding sites. The exchange of the tryptophan residues with analogs fluorinated at different positions resulted in three distinctly fluorinated variants of the lectin from Ralstonia solanacearum. We observed differences in stability and affinity toward fucosylated glycans and rationalized them by X-ray and modeling studies. While fluorination decreased the aromaticity of the indole ring and, therefore, the strength of carbohydrate-aromatic interactions, additional weak hydrogen bonds were formed between fluorine and the ligand hydroxyl groups. Our approach opens new possibilities to engineer carbohydrate receptors.
Controlled Growth of 15R-SiC Single Crystals by the Modified Lely Method (2000)

Bulk single crystals of the 15R-polytype of SiC have been grown by the sublimation physical-vapor-transport technique. 15R-SiC crystal growth was stabilized on a 15R-SiC seed using near-thermal-equilibrium growth conditions and a stoichiometric SiC sublimation source material. The polarity of the seed surface is shown to be an important factor in preparation of the 15R-polytype. The dual seed method (simultaneous growth on the Si- and C-face) was employed to demonstrate that 15R-polytype growth occurred only on the Si-face, while 6H- and 4H-polytype growth occurred on the C-face. The incorporation of nitrogen donors and boron acceptors was also shown to be a function of seed polarity, with nitrogen incorporation on the C-face two times that on the Si-face, and boron incorporation on the C-face one-half that on the Si-face.
SIMULTANEOUS EXPOSURE USING 532 AND 860 nm LASERS FOR VISIBLE LESION THRESHOLDS IN THE RHESUS RETINA (2006)

The growth of commercially available, simultaneous multi-wavelength laser systems has increased the likelihood of possible ocular hazard. For example, many systems utilize frequency multiplying methods to produce combinations of visible, near-infrared, and ultraviolet wavelengths. Unfortunately, very little data exists to substantiate the current methods for estimating hazards from simultaneous lasing. To properly assess the retinal hazards from these wavelengths, the retinal effects of 10-s laser irradiation from 532 and 860 nm were determined in non-human primates for four different relative dosage combinations of these wavelengths. This pair of wavelengths represents the typical problem of a visible-wavelength laser combined with an in-band, infrared wavelength that is not as well focused at the retina-a situation difficult to address. To add confidence to the experimental results obtained, a theoretical thermodynamic model was developed to predict the minimal damage threshold for simultaneous wavelengths at 1 h post exposure. The new model calculations and the data obtained are compared with results from one currently accepted method of predicting relative exposure limits from multi-wavelength systems. In addition, the current ANSI-Z136-2000 standard was used to compute the combined MPEs for comparison with measured visible lesion thresholds. A total of 12 eyes were exposed using four different ratios of power levels (532/860 power rations) to determine the contribution to the damage levels from each wavelength. The experimental data were analyzed using probit analysis at both 1-h and 24-h post exposure to determine the minimum-visible-lesion (MVL) thresholds at ED50 values, and these thresholds at 24 h varied from 5.6 mW to 17 mW total intraocular power.
La valutazione economica delle prestazioni tecniche dei componenti dell'involucro edilizio: i serramenti (2007)

Una corretta progettazione dell’involucro edilizio, alla luce del DLgs del 19 agosto 2005 “Attuazione della Direttiva 2002/91/CE relativa al rendimento energetico nell’edilizia” e del DPCM del 05/12/1997, “Determinazione dei requisiti acustici passivi degli edifici”, deve coinvolgere una valutazione economica-prestazionale delle caratteristiche termofisiche ed acustiche dei singoli elementi che lo compongono.&#13;\nIn particolare i serramenti, che costituiscono gli elementi “deboli” dell’involucro, devono rispettare, dal 1/1/2006, i valori di trasmittanza termica per le chiusure traparenti, compresi di infissi, in funzione della Zona Climatica, definiti nell’ Allegato C del D.Lgs 192/05, il quale, introduce nuovi limiti più restrittivi a partire dal 1/1/2008 e successivamente dal 1/1/2010; mentre il DPCM del 05/12/1997 definisce un indice di valutazione dell’isolamento acustico di facciata, D2m,nT,w, il cui valore è fortemente influenzato dalla presenza di serramenti, che molto spesso ne penalizzano l’efficienza.&#13;\n Il presente lavoro ha per oggetto lo studio globale delle prestazioni termiche ed acustiche dei serramenti di un edificio a schiera, ad uso civile abitazione, di prossima realizzazione.&#13;\nSecondo la norma UNI EN 12207 del 2000, che stabilisce cinque classi, 0, 1, 2, 3 e 4, di permeabilità all’aria (e sostitusce la UNI 7979 dove erano invece previste tre classi, A1, A2, A3 di permeabilità all’aria) e la UNI 11173 del 2005, si è condotto lo studio di quattro casi di serramenti analizzandone le prestazioni globali. La UNI 11173 del 2005 stabilisce, inoltre, le classi minime di permeabilità all’aria da rispettare in funzione di: zona di vento, altezza dell’edificio, zona climatica, classi di rugosità del terreno.
Classification of hand movements by using artificial neural network (2012)

In this study, a home-made four channel sEMG amplifier circuit was designed for measuring EMG signals. The recorded sEMG signals were filtered with a band pass filter and afterwards wavelet based filtering was applied to remove unwanted noises. As a second step the recorded and denoised signals' features were extracted. For classification of motions 8 time domain and 2 frequency domain features were used. There is no reduction applied to the features for artificial neural network (ANN) classification while the features were reduced in two dimension using by Diffusion Map for fuzzy classification. Lastly, seven different motions were classified by ANN and Gustafson Kessel algorithm. Also, their classification performances were compared.
Can imputation in a European country be improved by local reference panels? The example of France (2022)

Abstract France has a population with extensive internal fine-structure; and while public imputation reference panels contain an abundance of European genomes, there include few French genomes. Intuitively, using a ‘study specific panel’ (SSP) for France would therefore likely be beneficial. To investigate, we imputed 550 French individuals using either the University of Michigan imputation server with the Haplotype Reference Consortium panel, or in-house using an SSP of 850 whole-genome sequenced French individuals. With approximate geo-localization of both our target and SSP individuals we are able to pinpoint different scenarios where SSP-based imputation would be preferred over server-based imputation or vice-versa. We could also show to a high degree of resolution how the proximity of the reference panel to a target individual determined the accuracy of both haplotype phasing and genotype imputation. Previous comparisons of different strategies have shown the benefits of combining public reference panels with SSPs. Getting the best out of both resources simultaneously is unfortunately impractical. We put forward a pragmatic solution where server-based and SSP-based imputation outcomes can be combined based on comparing posterior genotype probabilities. Such an approach can give a level of imputation accuracy markedly in excess of what could be achieved with either strategy alone.
Antibody response to an autogenous vaccine and serologic profile for Streptococcus suis capsular type 1/2. (2002)

An autogenous vaccine was developed, using sonicated bacteria, with a strain of Streptococcus suis capsular type 1/2. The objectives of this study were to evaluate the antibody response following vaccination and to assess the changes in antibody levels in pigs from a herd showing clinical signs of S. suis capsular type 1/2 infection in 6- to 8-week-old pigs. An enzyme-linked immunosorbent assay using the vaccine antigen was standardized. Results from a preliminary study involving 2 control and 4 vaccinated 4-week-old pigs indicated that all vaccinated pigs produced antibodies against 2 proteins of 34 and 43 kDa, respectively, and, in 3 out of 4 vaccinated pigs, against the 117-kDa muramidase-released protein. For the serologic profile, groups of 30 pigs from the infected herd were blood sampled at 2, 4, 6, 8, and 10 weeks of age. The lowest antibody level was observed between weeks 6 and 8, presumably corresponding to a decrease in maternal immunity. A marked increase was seen at 10 weeks of age, shortly after the onset of clinical signs in the herd. For the vaccination field trial, newly weaned, one-week-old piglets were divided into 2 groups of 200 piglets each (control and vaccinated); blood samples were collected from 36 piglets in each group at 2-week intervals for 12 weeks. A significant increase (P < 0.05) in antibody response was observed 4 weeks following vaccination and the level of antibodies stayed high until the end of the experiment. In the control group, the increase was only observed at 13 weeks of age, probably in response to a natural infection. The response to the vaccine varied considerably among pigs and was attributed, in part, to the levels of maternal antibodies at the time of vaccination. No outbreak of S. suis was observed in the control or vaccinated groups, so the protection conferred by the vaccine could not be evaluated.
Iron Deposition in the Brain After Aneurysmal Subarachnoid Hemorrhage (2022)

After SAH, iron deposits in the cortical gray matter in a pattern that reflects proximity to the brain surface and thrombus and is related to cognitive outcome. These observations support therapeutic manoeuvres which prevent the permeation of hemoglobin into the cortex after SAH.
Endovascular Treatment for Acute Ischemic Stroke in Octogenarians Compared with Younger Patients: A Meta-Analysis (2013)

Formal meta-analysis showed that octogenarians are less likely to achieve functional independence and have higher rates of mortality and intracerebral hemorrhage following endovascular treatment for ischemic stroke compared with younger patients. Decisions regarding endovascular treatment of elderly patients should be individualized until randomized controlled trials are available.
Hormonal induction and antihormonal inhibition of tracheary element differentiation in Zinnia cell cultures (1988)

Mechanically isolated mesophyll cells of Zinnia elegans L. cv Envy differentiate to tracheary elements when cultured in inductive medium containing sufficient auxin and cytokinin. Tracheary element differentiation was induced by the three auxins (alpha-naphthaleneacetic acid, indole-3-acetic acid, and 2,4-dichlorophenoxyacetic acid) and four cytokinins (6-benzyladenine, kinetin, 2-isopentenyladenine and zeatin) tested. Tracheary element formation is inhibited or delayed if the inductive medium is supplemented with an anticytokinin, antiauxin, or inhibitor of auxin transport.
SCAI Expert Consensus Statement on Percutaneous Coronary Intervention Without On-Site Surgical Backup (2023)

Although once considered high-risk and below the standard of care, percutaneous coronary intervention (PCI) without on-site surgical backup has been performed with acceptable outcomes since the 1980s.1 An initial consensus document on PCI without surgery on site (no-SOS) was published by Society for Cardiovascular Angiography & Interventions (SCAI) in 2007 and updated in 2014.2,3 The 2014 document summarized new literature, reviewed existing guidelines and other publications related to PCI with no-SOS, and recommended best practices and requirements for facilities performing PCI with no-SOS.
Heptaprenyl pyrophosphate synthetase from Bacillus subtilis. (1980)

Heptaprenyl pyrophosphate synthetase was detected in partially purified extracts of Bacillus subtilis.The enzyme catalyzed the synthesis of all-trans ( $6 prenyl pyrophosphate from isopentenyl pyrophosphate and farnesyl or geranylgeranyl pyrophosphate, but it did not catalyze a reaction between isopentenyl pyrophosphate and either dimethylallyl or geranyl pyrophosphate.The enzyme reaction proceeded with an elimination of 2-pro-R hydrogen of isopentenyl pyrophosphate without accumulation of any prenyl pyrophosphate shorter than CS5.The molecular weight of the enzyme was estimated by gel filtration to be 45,000.Michaelis constants for isopentenyl, farnesyl, and geranylgeranyl pyrophosphate were 12.8, 13.3, and 8.3 p ~, respectively.
Performance of an Adaptive Threshold Receiver in a Dynamic Optical Burst-Switched Network (2008)

We compare the performance of a digital receiver operating with both a fixed and adaptive decision threshold in response to gain transients arising from network operation of an optically gain-clamped erbium-doped fiber amplifier. An optical burst switching link, based on a recirculating transmission loop, is used to study the effect of transients accumulated across a number wavelength-routing nodes linked by amplified fiber spans where bursts are added and dropped at each node. The use of an adaptive threshold reduces the amount of optical feedback required by a factor of 6 and, in some cases, allows for unclamped operation.
Tolterodine, a new antimuscarinic agent: as effective but better tolerated than oxybutynin in patients with an overactive bladder (1998)

Tolterodine 2 mg twice daily is effective and well tolerated in the treatment of bladder overactivity. Tolterodine was better tolerated than oxybutynin, particularly with respect to the frequency and intensity of dry mouth, but had comparable clinical efficacy. The superior tolerability of tolterodine therefore allows more patients to remain on effective therapy than the current most commonly prescribed agent for the treatment of the overactive bladder.