gebhart/patrepeval huggingface dataset:
OPC UA for plug & produce: Automatic device discovery using LDS-ME (2017)

Current manufacturing and production are changing more and more into a flexible and adaptable factory layout that requires rapid changeover and short reconfiguration times of machines. Additionally the setup time for new devices should be as short as possible. In this paper we propose a hierarchical architecture for a multi-level Plug & Produce system and evaluate the proposed structure using open source OPC UA implementations for easy integration of new devices into an existing system. Aside from the requirements for such a system, basic concepts of the OPC UA Discovery Service Set are described and different open source OPC UA implementations for C/C++ and Java are compared.
QoE-Driven Channel Allocation and Handoff Management for Seamless Multimedia in Cognitive 5G Cellular Networks (2016)

Cognitive radio (CR) is among the promising solutions for overcoming the spectrum scarcity problem in the forthcoming fifth-generation (5G) cellular networks, whereas mobile stations are expected to support multimode operations to maintain connectivity to various radio access points. However, particularly for multimedia services, because of the time-varying channel capacity, the random arrivals of legacy users, and the on-negligible delay caused by spectrum handoff, it is challenging to achieve seamless streaming leading to minimum quality of experience (QoE) degradation. The objective of this paper is to manage spectrum handoff delays by allocating channels based on the user QoE expectations, minimizing the latency, providing seamless multimedia service, and improving QoE. First, to minimize the handoff delays, we use channel usage statistical information to compute the channel quality. Based on this, the cognitive base station maintains a ranking index of the available channels to facilitate the cognitive mobile stations. Second, to enhance channel utilization, we develop a priority-based channel allocation scheme to assign channels to the mobile stations based on their QoE requirements. Third, to minimize handoff delays, we employ the hidden markov model (HMM) to predict the state of the future time slot. However, due to sensing errors, the scheme proactively performs spectrum sensing and reactively acts handoffs. Fourth, we propose a handoff management technique to overcome the interruptions caused by the handoff. In such a way that, when a handoff is predicted, we use scalable video coding to extract the base layer and transmit it during a certain interval time before handoff occurrence to be shown during handoff delays, hence providing seamless service. Our simulation results highlight the performance gain of the proposed framework in terms of channel utilization and received video quality.
Entanglement without indistinguishability: Routing of coupling-induced path-entangled photon pairs (2017)

Realizing an on-chip reconfigurable source of path-entangled photons is of critical importance for the advancement of quantum information processing and networking. Achieving this goal has proven challenging to date. We present an on-chip scheme for the deterministic creation of co-propagating or counter-propagating path-entangled photon pairs that can be routed in multiple configurations by tuning a classical parameter. The simplest manifestation of this approach makes use of two \textit{coupled} waveguides: a \textit{nonlinear} waveguide that produces photon pairs via spontaneous parametric downconversion from an externally incident unguided optical pump, and an auxiliary \textit{linear} waveguide. Although the photon pairs are born in only one waveguide, which alone cannot create path-entanglement, linear coupling over an extended length to the passive waveguide introduces unexpected indistinguishability that induces path-entanglement. Tuning of the classical pump spatial profile allows routing the photon pairs over all possible configurations. The proposed device is a building block for future quantum-optical networks.
Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy (2013)

Primary open angle glaucoma (POAG) is one of the main causes of irreversible blindness worldwide. The pathogenesis of POAG is still unclear. Alteration and sclerosis of trabecular meshwork with changes in aqueous humor molecular composition seem to play the key role. Increased intraocular pressure is widely known to be the main risk factor for the onset and progression of the disease. Unfortunately, the early diagnosis of POAG still remains the main challenge. In order to provide insight into the patho-physiology of glaucoma, here we report a shotgun proteomics approach to tears of patients with POAG naïve to therapy. Our proteomics results showed 27 differential tear proteins in POAG vs. CTRL comparison (25 up regulated proteins in the POAG group and two unique proteins in the CTRL group), 16 of which were associated with inflammatory response, free radical scavenging, cell-to-cell signaling and interaction. Overall the protein modulation shown in POAG tears proves the involvement of biochemical networks linked to inflammation. Among all regulated proteins, a sub-group of 12 up-regulated proteins in naïve POAG patients were found to be down-regulated in medically controlled POAG patients treated with prostanoid analogues (PGA), as reported in our previous work (i.e., lipocalin-1, lysozyme C, lactotransferrin, proline-rich-protein 4, prolactin-inducible protein, zinc-alpha-2-glycoprotein, polymeric immunoglobulin receptor, cystatin S, Ig kappa chain C region, Ig alpha-2 chain C region, immunoglobulin J chain, Ig alpha-1 chain C region). In summary, our findings indicate that the POAG tears protein expression is a mixture of increased inflammatory proteins that could be potential biomarkers of the disease, and their regulation may be involved in the mechanism by which PGA are able to decrease the intraocular pressure in glaucoma patients.
Linear Interference Cancellation for Downlink Map Reception in IEEE 802.16E (2006)

Next generation wireless systems, such as the IEEE 802.16e specification, are designed to provide great flexibility in scheduling radio resources on a per frame basis. Such flexibility, coupled with the need to maintain good quality of service (QoS) for cell-edge users can, however, lead to significant control channel overhead especially when using low code rates to maintain cell edge coverage. It is shown here that in interference-limited scenarios dual antenna mobile stations (MS) equipped with interference cancellation (IC) receivers can significantly alleviate this problem. In this study, the performance of a linear MMSE IC receiver is evaluated both at the link level and at the network level. It is shown that a practical IC receiver can achieve link performance gains in the range of 2.5-14 dB over a maximal ratio combining (MRC) receiver in single interferer dominant conditions. Performance at the network level is evaluated using the well-known EESM method to model the link-level performance for OFDM systems, and the introduction of IC receivers at the MS is shown to increase control channel coverage by 10-24% at low codeword repetition factors
Immune activation in HIV/HCV-infected patients is associated with low-level expression of liver expressed antimicrobial peptide-2 (LEAP-2) (2013)

Our data suggests that HCV and HIV infections are associated with decreased expression of LEAP-2 in colonic tissue. This may represent a key mechanism for enhanced microbial translocation and immune activation in HIV/HCV-infected patients.
Improved Sulfur-Reacting Microcoulometric Cell for Gas Chromatography. (1966)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTImproved Sulfur-Reacting Microcoulometric Cell for Gas Chromatography.D. F. Adams, G. A. Jensen, J. P. Steadman, R. K. Koppe, and T. J. RobertsonCite this: Anal. Chem. 1966, 38, 8, 1094–1096Publication Date (Print):July 1, 1966Publication History Published online1 May 2002Published inissue 1 July 1966https://pubs.acs.org/doi/10.1021/ac60240a045https://doi.org/10.1021/ac60240a045research-articleACS PublicationsRequest reuse permissionsArticle Views19Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Smooth patchy control Lyapunov functions (2006)

A smooth patchy control Lyapunov function for a nonlinear system consists of an ordered family of smooth local control Lyapunov functions, whose open domains form a locally finite cover of the state space of the system, and which satisfy a decrease condition when the domains overlap. We prove that such a control Lyapunov function exists for any asymptotically controllable nonlinear system. We also show a construction, based on such a Lyapunov function, of a stabilizing hybrid feedback that is robust to measurement noise
Informal carers of the dementing elderly: A study of relationships (1991)

The role of informal carers in the UK has been a cause of considerable concern recently and has been highlighted by the Government's legislation of 1988 ( 1 ).
Patterns of laccase and peroxidases in coarse woody debris of Fagus sylvatica, Picea abies and Pinus sylvestris and their relation to different wood parameters (2015)

Lignin and its degradation, particularly in forest ecosystems, play a major role in the global carbon cycle. Filamentous fungi equipped with extracellular oxidoreductases (oxidative enzymes), i.e., laccase, manganese-dependent peroxidases and several other peroxidases, are the key players in the bioconversion of lignin. In particular, for coarse woody debris (CWD), this process is poorly understood and the activities of laccase and peroxidases have never been studied on a large field scale. We investigated the activities of these enzymes in 701 samples of Fagus sylvatica, Picea abies and Pinus sylvestris CWD across three regions in Germany and analyzed their dependence on pH, water content, wood density, total lignin, organic extractives, metals, watersoluble lignin fragments and fungal species richness. Respective enzyme activities were present in 79 % of all samples, and the activities were highly variable and more frequent in F. sylvatica than in coniferous wood. Logistic regressions and correlations between enzyme activities and the variables revealed that the fungal community structure and the amount of water-soluble lignin fragments are most important determinants, and that the prevalent acidic pH in CWD is suitable to facilitate laccase and manganese peroxidase activities. Concentrations of metals (manganese, copper, iron) were sufficient to ensure synthesis and functioning of relevant enzymes. Based on this large field study, we conclude that laccase and peroxidases in CWD are highly relevant for lignin degradation, but the variable pattern of their secretion is the result of a complex array of wood parameters and the fungal community structure, which could only partly be resolved.
Reliability differentiation in energy efficient optical networks with shared path protection (2013)

Energy and resource efficiency are two contrasting objectives to optimize in dynamic and survivable optical networks. Known solutions for improving the energy efficiency include the use of the shared path-protection (SPP) mechanism and of a low power consuming mode (i.e., sleep) for protection resources. On the other hand, resource efficiency can be improved by introducing the concept of Differentiated Reliability (DiR) which can be combined with SPP in order to match the level of provisioned protection resources to the reliability requirements for each specific demand. This paper assesses the energy efficiency of the DiR concept combined with SPP and sleep mode support. A multi-objective optimization algorithm is proposed with the intent of jointly optimizing the energy and resource efficiency when dynamically establishing lightpaths with specific reliability levels. Simulation results show that when the proposed multi-objective cost function is properly tuned, not only the SPP-based DiR approach reduces the blocking probability but it is also able to save power for any network load. By enabling sleep mode additional power savings can be achieved at low loads, leading to an overall saving of up to 25%.
White Light Effects on the mRNA for the Light-Harvesting Chlorophyll a/b-Protein in Lemna gibba L. G-3 (1981)

Translation products of poly(A) mRNA isolated from Lemna gibba L. G-3 include a major polypeptide of 32,000 daltons which is immunoprecipitated by antiserum to chlorophyll a/b-protein from Chlamydomonas. This 32,000 dalton polypeptide represents a precursor to the light-harvesting chlorophyll a/b-protein of molecular weight 28,000 found in the thylakoid membranes of Lemna gibba. The amount of this translatable mRNA decreases relative to other translatable mRNAs when green plants grown in continuous white light are placed in darkness. This decrease occurs rapidly. The most rapid decline occurs during the first day; after 4 days of darkness, only a low level of this mRNA can be detected by in vitro translation. When the plants are returned to white light there is an increase in the relative level of this mRNA which can be easily detected within two hours. The in vivo synthesis of this protein has been assayed under the different light conditions. The light effects on the in vivo synthesis of the chlorophyll a/b-protein reflect the light effects on the translatable mRNA for the polypeptide. The results indicate that light induced changes in the synthesis, processing, or degradation of chlorophyll a/b-protein mRNA could account for the light-induced changes observed in the effective synthesis rates for the chlorophyll a/b-protein in vivo.
What makes them tick? (2015)

Real success of projects and people is one of the great drivers to make one's bosses and management really tick. There are so many factors that influence the perception of success, which go far beyond sheer expression of success through sales figures. This chapter presents the discovery of important elements to win the support of one's superiors for their important project. It discusses about the need for an optimal project mix as a crucial and decisive element for the decision going in one's way. The chapter suggests that instilling a feeling of sentiment in the decision-maker's mood can often be a great, almost subliminal element to make the dice fall one's way. It also discusses the parallels of group dynamics in companies with TV reality shows and suggested that one not only recognize such dynamics, but become an expert in playing them in one's favor.
Antihypercholesterolemic activity of .BETA.-sitostanol in rabbits. (1981)

The antihypercholesterolemic activity of beta-sitosterol and beta-sitostanol was compared in male rabbits given a cholesterol-supplemented diet. beta-Sitosterol and beta-sitostanol were fed to these rabbits at the 0.5% level with cholesterol (0.5% and 0.2% in experiments I and II, respectively). The serum cholesterol level tended to be lower in rabbits fed beta-sitostanol than in the animals fed beta-sitosterol even in experiment I. The beta-sitostanol exhibited a significantly greater hypocholesterolemic activity in experiment II, LDL-cholesterol being decreased markedly. The liver cholesterol decreased in both groups of rabbits to a similar extent. beta-Sitostanol prevented more effectively the formation of dietary cholesterol-induced atheroma in the abdominal aorta than beta-sitosterol. It is most likely, together with the data reported previously on rats, that the hypocholesterolemic activity of beta-sitostanol results from the significantly greater inhibitory effect on the intestinal absorption of cholesterol than that of beta-sitosterol.
Fast Iterative-Interpolated DFT Phasor Estimator Considering Out-of-Band Interference (2022)

For interpolated discrete Fourier transform (IpDFT)-based phasor estimators, the out-of-band interference (OOBI) test is among the most challenging ones. The typical iterative-interpolated DFT (i-IpDFT) phasor estimator utilizes a two-step iterative framework to eliminate the effects of the negative frequency and OOBI. However, the speed of estimation is limited by the adopted frequency estimator and the redundant iterations. To this end, this article proposes a fast i-IpDFT (FiIpDFT) method for the phasor estimation of an OOBI contaminated signal, which utilizes the three-point IpDFT (I3pDFT) technique. The proposed method first applies a noniterative frequency, amplitude, and phase estimator to eliminate the negative frequency interference. Then, a straightforward formula and two-stop criterion are introduced to reduce the computational burden of the OOBI elimination process. The accuracy and effectiveness of the proposed FiIpDFT method are validated by simulations. These are designed, under steady and dynamic conditions, according to the requirements of the Standard IEC/IEEE 60255-118-1.
Applications of optical coherence tomography to cardiac and musculoskeletal diseases: bench to bedside? (2007)

Selected historical aspects of the transition of optical coherence tomography (OCT) research from the bench to bedside are focused on. The primary function of the National Institutes of Health (NIH) is to improve the diagnosis and treatment of human pathologies. Therefore, research funded by the NIH should have a direct envisioned pathway for transitioning bench work to the bedside. Ultimately, to be successful, this work must be accepted by physicians and by the general science community. This typically requires robustly validated hypothesis-driven research. Work that is not appropriately compared to the current gold standard or does not address a specific pathology is unlikely to achieve widespread acceptance. I outline OCT research in the musculoskeletal and cardiovascular systems, examining the rapid transition from bench to bedside and look at initial validated hypothesis-driven research data that suggested clinical utility, which drove technology development toward specific clinical scenarios. I also consider the time of initial funding compared to when it was applied in patients with clinical pathologies. Finally, ongoing bench work being performed in parallel with clinical studies is examined. The specific applications examined here are identifying unstable coronary plaque and the early detection of osteoarthritis, the former was brought to the bedside primarily through a commercial route while the latter through NIH-funded research.
Direct costs of chronic obstructive pulmonary disease among managed care patients (2010)

Direct costs of COPD-related care for commercially insured patients are driven by hospital stays with or without ICU care. Exacerbation prevention resulting in reduced need for inpatient care could lower costs.
Clinical efficacy of doxifluridine and correlation to in vitro sensitivity of anticancer drugs in patients with colorectal cancer. (2003)

5'-DFUR sensitivity test results and TP values may predict the clinical effects of this drug in colorectal cancer.
Quantum and semi-classical transport in RTDs using NEMO 1-D (2003)

NEMO 1-D has been developed primarily for the simulation of resonant tunneling diodes, and quantitative and predictive agreements with experimental high performance, high current density devices have been achieved in the past.
Conventional Electron Diffraction Pattern Analysis for Crystallographic Orientation of Crystalline Domains in a Nd-Fe-Co-B-Ga Powder Particle (1994)

Crystallographic orientation of fine crystalline domains in magnet powder of Nd-Fe-Co-B-Ga produced by the hydrogenation-decompositlon-desorption-recombination (HDDR) method has been examined from their conventional selected area electron diffraction patterns. It was found that the c- and a-axes of domains (Nd2Fe14B-type: P42mnm) are aligned within 45° in solid angle, respectively. The correlated alignment of c-axes accounts for the magnetic anisotropy of the magnet powder.
c-Jun Reprograms Schwann Cells of Injured Nerves to Generate a Repair Cell Essential for Regeneration (2012)

The radical response of peripheral nerves to injury (Wallerian degeneration) is the cornerstone of nerve repair. We show that activation of the transcription factor c-Jun in Schwann cells is a global regulator of Wallerian degeneration. c-Jun governs major aspects of the injury response, determines the expression of trophic factors, adhesion molecules, the formation of regeneration tracks and myelin clearance and controls the distinctive regenerative potential of peripheral nerves. A key function of c-Jun is the activation of a repair program in Schwann cells and the creation of a cell specialized to support regeneration. We show that absence of c-Jun results in the formation of a dysfunctional repair cell, striking failure of functional recovery, and neuronal death. We conclude that a single glial transcription factor is essential for restoration of damaged nerves, acting to control the transdifferentiation of myelin and Remak Schwann cells to dedicated repair cells in damaged tissue.
Bordetella pertussis Respiratory Tract Infection in the Mouse: Pathophysiological Responses (1980)

The influence of living Bordetella pertussis on the induction and duration of pathophysiological reactions in mice infected intranasally with graded doses of culture was studied. Lethally infected mice showed loss of body weight, spleen atrophy, pronounced hypothermia and hypoglycemia, and highly elevated levels of leukocytes and serum immunoreactive insulin. Sublethally infected mice showed normal weight gain, practically normal temperature, spleen enlargement, lesser pronounced hypoglycemia, lower but significantly elevated levels of leukocytes and serum immunoreactive insulin, and histamine sensitization. Intensity of each reaction was related to the degree of lung infectivity. Hypothermia and leukocytosis were highly correlated. Concentration of serum immunoreactive insulin was closely related to the level of leukocytosis but not to the level of glucose. The strain and age of mice significantly affected the degree and duration of the reactions. The results suggest that the intranasally infected mouse may provide a useful model for investigations on whooping cough.