gebhart/patrepeval huggingface dataset:
Induction of fibrinolytic activity in HeLa cells by phorbol myristate acetate. Tissue-type plasminogen activator antigen and mRNA augmentation require intermediate protein biosynthesis. (1985)

The highly increased fibrinolytic activity of HeLa cells, treated with the tumor promoting phorbol ester, phorbol myristate acetate (PMA), correlates with equally increased levels of tissue-type plasminogen activator (t-PA) antigen in the conditioned media of these cells and concomitantly increased steady state levels of t-PA-specific mRNA. The effect of PMA on t-PA mRNA levels is completely blocked by pretreatment of the cells with the inhibitor of translation, cycloheximide, indicating that it requires the biosynthesis of at least one protein intermediate. In contrast, mRNA of the oncogene product c-myc can be induced for a brief period immediately following serum starvation in the presence and absence of PMA, and in the presence of cycloheximide. Our results suggest that increased t-PA biosynthesis in HeLa cells, probably through an increased rate of translation of the t-PA gene, forms part of the "late" events of the pleiotropic response to tumor promoters.
A Switchless Multiband Impedance Matching Technique Based on Multiresonant Circuits (2013)

In a number of applications, a matching network capable of providing specified impedances at different frequencies is necessary. In this brief, we present a novel technique for switchless multiband impedance matching networks based on multiresonant circuits. To illustrate this, simulation results of dual-band and triband networks are also presented. In addition, a dual-band impedance matching network has been implemented and evaluated. The dual-band impedance matching network presents two specified impedances, one at 433 MHz and the other at 915 MHz with 0.82 and 0.20 dB of insertion losses, respectively.
A run-time word-level reconfigurable coarse-grain functional unit for a VLIW processor (2002)

Nowadays, new DSP applications are offering combined and flexible multimedia and telecom services. VLIW processor architectures, which include dedicated but inflexible functional units, are usually tuned to a single specific application. In order to accelerate a wide range of applications, we propose a VLIW processor containing a novel run-time reconfigurable functional unit (RC-FU). Only a few hundred bits and few cycles are necessary to configure a new coarse-grain operation on the RC-FU unit. After reconfiguring its internal datapath and micro-program, the RC-FU can execute a number of look-alike DSP functions, such as 8-point DCT or 4-point FFT. The RC-FU itself is a VLIW processor and the configuration contexts are generated using a high-level synthesis tool. The proposed RC-FU provides high processing power and can be efficiently tuned to the requirements of a variety of DSP applications.
Effect of Various Encapsulating Materials on the Stability of Probiotic Bacteria (2009)

Ten probiotic bacteria, including Lactobacillus rhamnosus, Bifidobacterium longum, L. salivarius, L. plantarum, L. acidophilus, L. paracasei, B. lactis type Bl-04, B. lactis type Bi-07, HOWARU L. rhamnosus, and HOWARU B. bifidum, were encapsulated in various coating materials, namely alginate, guar gum, xanthan gum, locust bean gum, and carrageenan gum. The various encapsulated probiotic bacteria were studied for their acid and bile tolerance. Free probiotic organisms were used as a control. The acid tolerance of probiotic organisms was tested at pH 2 over a 2-h incubation period. Bile tolerance was tested with taurocholic acid over an 8-h incubation period. The permeability of the capsules was also examined using a water-soluble dye, 6-carboxyflourescin (6-CF). The permeability was monitored by measuring the amount of 6-CF released from the capsules during a 2-w storage period. Results indicated that probiotic bacteria encapsulated in alginate, xanthan gum, and carrageenan gum survived better (P < 0.05) than free probiotic bacteria, under acidic conditions. When free probiotic bacteria were exposed to taurocholic acid, viability was reduced by 6.36 log CFU/mL, whereas only 3.63, 3.27, and 4.12 log CFU/mL was lost in probiotic organisms encapsulated in alginate, xanthan gum, and carrageenan gum, respectively. All encapsulating materials tested released small amounts of 6-CF; however, alginate and xanthan gum retained 22.1% and 18.6% more fluorescent dye than guar gum. In general, microcapsules made of alginate, xanthan gum, and carrageenan gum greatly improved the survival of probiotic bacteria when exposed to acidic conditions and bile salts.
Adaptive Antenna Systems (1967)

A system consisting of an antenna array and an adaptive processor can perform filtering in both the space and frequency domains, thus reducing the sensitivity of the signal-receiving system to interfering directional noise sources. Variable weights of a signal processor can be automatically adjusted by a simple adaptive technique based on the least-mean-squares (LMS) algorithm. During the adaptive process an injected pilot signal simulates a received signal from a desired “look” direction. This allows the array to be “trained” so that its directivity pattern has a main lobe in the previously specified look direction. At the same time, the array processing system can reject any incident noises, whose directions of propagation are different from the desired look direction, by forming appropriate nulls in the antenna directivity pattern. The array adapts itself to form a main lobe, with its direction and bandwidth determined by the pilot signal, and to reject signals or noises occurring outside the main lobe as well as possible in the minimum mean-square error sense. Several examples illustrate the convergence of the LMS adaptation procedure to the corresponding Wiener-optimum solutions. Rates of adaptation and misadjustments of the solutions are predicted theoretically and checked experimentally. Substantial reductions in noise reception are demonstrated in computer-simulated experiments. The techniques described in this paper are applicable to signal-receiving arrays for use over a wide range of frequencies.
Displaced Filtering for Patterned Displays (2000)

This paper describes the filtering used in Microsoft ClearType. ClearType is a software system that enhances the resolution and readability of fonts on displays that contain a repeating pattern of addressable colored sub-pixels. The filtering in ClearType is based on a perceptual model of human vision. The perceptual model leads to an optimization technique for finding the best output values. The results of the optimization can be approximated by pre-filtering each color channel of an input image and then sampling each filtered color image at the spatial locations of the same colored sub-pixels in the display. We refer to this filtering followed by displaced sampling as RGB decimation. RGB decimation eliminates the phase error caused by standard anti-aliasing. A further approximation of the optimal filter yields RGB decimation with displaced box filters. Fourier analysis demonstrates that both the optimization technique and the displaced box filter suppress frequencies that contribute most to color fringing in unfiltered displaced sampling.
Mechanical spectrum analyzer in silicon using micromachined accelerometers with time-varying electrostatic feedback (2004)

Capacitive accelerometers with electrostatic force feedback are widely employed, because of performance and robustness. The force feedback acts as a means for electronic modulation of the spring constant of the suspension. Commonly, the electrostatic feedback is employed for null-based acceleration measurement. A suitable electrostatic time-varying actuation could instead be used to make the accelerometer selectively sensitive to a coherent mechanical frequency component. By sweeping the frequency of the drive voltage over a selected range, the mechanical spectrum is analyzed in the mechanical domain. The resulting spectrum analyzer features many advantages compared to conventional techniques for condition monitoring of mechanical machines. An inverted pendulum type of accelerometer structure has been fabricated in silicon using micromachining techniques and operated using electrostatic momentum feedback.
In Situ Neutron Diffraction Study on the Mechanical Behavior of an Ultra-Fine-Grained Steel (2006)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
Laparoscopic-Assisted Intraperitoneal Chemotherapy for Patients with Scirrhous Gastric Cancer (2005)

IPC effectiveness may correlate with elevation of gene expression of inflammatory cytokines, such as IL-2 and IL-6 in the peritoneal cavity after IPC. However, the prognostic benefits of IPC for SGC patients remain unclear.
Experimental observation of TiN12+ cluster and theoretical investigation of its stable and metastable isomers (2015)

TiN <sub><i>n</i></sub><sup>+</sup> clusters were generated by laser ablation and analyzed experimentally by mass spectrometry. The results showed that the mass peak of the TiN<sub>12</sub><sup>+</sup> cluster is dominant in the spectrum. The TiN<sub>12</sub><sup>+</sup> cluster was further investigated by photodissociation experiments with 266, 532 and 1064 nm photons. Density functional calculations were conducted to investigate stable structures of TiN<sub>12</sub><sup>+</sup> and the corresponding neutral cluster, TiN<sub>12</sub>. The theoretical calculations found that the most stable structure of TiN<sub>12</sub><sup>+</sup> is Ti(N<sub>2</sub>)<sub>6</sub><sup>+</sup> with <i>O</i><sub>h</sub> symmetry. The calculated binding energy is in good agreement with that obtained from the photodissociation experiments. The most stable structure of neutral TiN<sub>12</sub> is Ti(N<sub>2</sub>)<sub>6</sub> with <i>D</i><sub>3d</sub> symmetry. The Ti-N bond strengths are greater than 0.94 eV in both Ti(N<sub>2</sub>)<sub>6</sub><sup>+</sup> and its neutral counterpart. The interaction between Ti and N<sub>2</sub> weakens the N-N bond significantly. For neutral TiN<sub>12</sub>, the Ti(N<sub>3</sub>)<sub>4</sub> azide, the N<sub>5</sub>TiN<sub>7</sub> sandwich structure and the N<sub>6</sub>TiN<sub>6</sub> structure are much higher in energy than the Ti(N<sub>2</sub>)<sub>6</sub> complex. The DFT calculations predicted that the decomposition of Ti(N<sub>3</sub>)<sub>4</sub>, N<sub>5</sub>TiN<sub>7</sub>, and N<sub>6</sub>TiN<sub>6</sub> into a Ti atom and six N<sub>2</sub> molecules can release energies of about 139, 857, and 978 kJ mol<sup>-1</sup> respectively.
Membrane filter method for isolation and characterization of thermophilic bacteria. (1981)

Wehave reported the isolation of various thermophilic bacteria from extreme environments such as hot springs1* and hot compost samples.2) During growth experiments for the isolated thermophiles we find difficulties in growing them on agar plates at high temperature about 70C. It was often encountered that even dense cell suspension samples from their log phase growth cultures formed no colonies on agar plates, or if any, muchfewer colonies than expected from total cell number. The troubles are likely due to unusual physical conditions on agar plates at high temperature that is, for example, quick evaporation of moisture which is unfavorable for thermophiles to grow and form colonies. Colony forming efficiency can be improved by several methods such as water vapor saturation,3)
Response characteristics of ion selective electrodes based on dinonylnaphthalenesulfonic acid (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTResponse characteristics of ion selective electrodes based on dinonylnaphthalenesulfonic acidCharles R. Martin and Henry. FreiserCite this: Anal. Chem. 1980, 52, 3, 562–564Publication Date (Print):March 1, 1980Publication History Published online1 May 2002Published inissue 1 March 1980https://doi.org/10.1021/ac50053a042Request reuse permissionsArticle Views160Altmetric-Citations64LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (424 KB) Get e-Alertsclose Get e-Alerts
Sad Macs, Bombs, and Other Disasters: And What to Do about Them (1993)

From the Publisher:
Here is the most comprehensive 911 disaster relief Mac reference available. Designed to restore order quickly, Sad Macs, Bombs, and Other Disasters provides solutions to hundreds of problems with a Symptom Index listing every error message and major problem, as well as self-contained Fix-It sections that delve into the details of the most important and useful techniques for solving problems. . . . the hardware and software troubleshooting guide that ought to ship with every Mac.--Andy Ihnatko, MacUser.
The importance of the interpretation of urine catecholamines is essential for the diagnosis and management of patient with dopamine-secreting paraganglioma (2005)

Phaeochromocytoma or paraganglioma that exclusively secretes dopamine is very rare. This case illustrates its atypical presentation and the importance of interpretative reporting for urine catecholamines leading to the diagnosis and subsequent management of a patient with this condition. We report a 71-year-old Chinese woman with a large dopamine-secreting paraganglioma. She presented with low back pain for six months. On examination, a right abdominal mass was palpable incidentally. Her blood pressure was normal throughout. Serial 24-h urine collections for catecholamines showed enormous elevation of urine dopamine excretion to 80.7 micromol/day (normotensive:<2.6 m mol/day). However, the daily excretions of urine adrenaline and noradrenaline, as well as their metabolites were within their respective reference intervals. Good communication between chemical pathologists and physicians prompted the arrangement of the whole body 131I-meta-iodobenzylguanidine (MIBG) scintigraphy, which showed a large signal in the right upper quadrant of the abdomen corresponding to a large extra-adrenal tumour detected by both ultrasonography and computerized tomography (CT) of the abdomen. Histological section of the tumour tissue revealed paraganglioma, which stained positive for chromogranin and neuron-specific enolase. After four months, the patient presented with chest symptoms and CT of the thorax revealed multiple nodules. Lung metastases were suspected. However, follow-up urine catechola- mine and dopamine excretions were again within their respective normotensive reference intervals. A second MIBG scintigraphy was performed, but no specific uptake at either the thorax or the abdomen could be demonstrated. Fine-needle aspiration cytology using the thoracoscopic technique was performed and immunochemical staining of the biopsy specimen showed the presence of non- small-cell carcinoma of the lung.
Beyond ExaBricks: GPU Volume Path Tracing of AMR Data (2022)

Adaptive Mesh Refinement (AMR) is becoming a prevalent data representation for scientific visualization. Resulting from large fluid mechanics simulations, the data is usually cell centric, imposing a number of challenges for high quality reconstruction at sample positions. While recent work has concentrated on real-time volume and isosurface rendering on GPUs, the rendering methods used still focus on simple lighting models without scattering events and global illumination. As in other areas of rendering, key to real-time performance are acceleration data structures; in this work we analyze the major bottlenecks of data structures that were originally optimized for camera/primary ray traversal when used with the incoherent ray tracing workload of a volumetric path tracer, and propose strategies to overcome the challenges coming with this.
New Insights Towards Aging Resistant Li-ion Polymer Batteries For Wide Temperature Applications (2016)

A wide interest is mounting towards polymer electrolytes, due to their application in energy efficient rechargeable batteries, photo-electrochemical cells, electrochromics, and supercapacitors. Polymer electrolytes exhibit unique advantages such as mechanical integrity, wide variety of fabrication methods in desirable size and shape, possibility to fabricate an intimate electrode/electrolyte interface and adapt to a lightweight, leak-proof construction, and economic packaging structure. In this communication, we offer a summary of our recent results regarding the synthesis, physico-chemical and electrochemical characterization of solid polymer electrolytes (SPEs) based on different monomers/oligomers (methacrylic and/or ethylene oxide based) with specific amounts of lithium salt, plasticizers and/or fillers. Profoundly ion conducting (σ &gt; 10-4 S cm-1 at 20 °C), electrochemically stable (&gt; 5 V vs. Li), self-standing, robust and tack-free SPEs are successfully prepared via a rapid and easily up-scalable process including a light and/or thermally induced polymerization step. The resulting crosslinking allows the incorporation of high amounts of plasticisers (e.g., RTILs) and lithium salt (based on TFSI- anion), leading to a material with remarkable morphological characteristics in terms of homogeneity and mechanical abusability under highly stressful conditions. Lab-scale Li-polymer cells assembled show stable charge/discharge characteristics without any capacity fading at C/5 current regime (&gt; 130 mAh g-1 in LiFePO4/Li configuration and &gt; 150 mAh g-1 in TiO2/Li configuration even @ 20 °C). The overall performance of the SPEs postulates the possibility of effective implementation in the next generation of safe, durable and high energy density secondary all-solid Li-ion polymer batteries working at ambient and/or sub-ambient temperatures
Magnetic and mechanical properties of micromachined strontium ferrite/polyimide composites (1997)

In this work, strontium ferrite/polyimide composite thin films are fabricated and characterized for micromachining applications. The application of these materials in microelectronics and micromachining dictates the use of different polymers than those previously used for conventional plastic magnets due to fabrication compatibility constraints. The material investigated here consists of magnetically anisotropic strontium ferrite particles suspended in a benzophenone tetracarboxylic dianhydride-oxydianiline/metaphenylene diamine polyimide matrix. Magnetic mechanical, and processability properties of these composites are investigated for a strontium ferrite loading range of 55%-80% by volume. Intrinsic coercivity H/sub ci/ residual magnetic flux density B/sub r/ and maximum energy product (BH)/sub max/ have been determined. For an 80% by-volume concentration loading of ferrite, H/sub ci/ of 318 kA/m B/sub r/, approaching 0.3 T, and (BH)/sub max/ of 11900 T/spl middot/A/m have been achieved. Biaxial Young's modulus and residual stress are determined using a slightly modified in situ load/deflection technique. The biaxial Young's modulus increases with increasing the magnetic powder loading. The materials have been deposited and patterned using two techniques: (1) screen-printing and (2) spin-casting, followed by photolithography. Finally, a simple magnetic microactuator made with those materials has been fabricated and tested, which demonstrates the usefulness of those materials to micromachining.
Human B cells accumulate immunoglobulin V gene somatic mutations in a cell contact-dependent manner in cultures supported by activated T cells but not in cultures supported by CD40 ligand (1999)

The acquisition of somatic mutations in the rearranged immunoglobulin V regions in B cells occurs within the tightly regulated microenvironment of a germinal centre. The precise mechanism responsible for turning on the mutational process is unknown. To dissect the role of different components of the germinal centre in this mechanism, we have used in vitro cultures of normal human IgD+ peripheral blood B lymphocytes co-cultured with activated CD4+ T cells, or with resting CD4+ T cells, or with CD40 ligand and IL-4. We observed that if the cultures included activated CD4+ T cells, then up to 100% of VH transcripts on day 14 were somatically mutated. Transcripts were found to carry from one to 36 substitutions (median five). In contrast, in the absence of activated T cells, transcripts contained only background levels of somatic mutation irrespective of the presence of resting T cells or CD40 ligand and IL-4. Cell-cell contact was required for mutation because mutations were not detected when B cells were separated from activated T cells by a membrane.
Optimized Nanostructured Lipid Carriers Integrated into in situ Nasal Gel for Enhancing Brain Delivery of Flibanserin [Retraction] (2023)

[This retracts the article DOI: 10.2147/IJN.S258791.].
Synergistic Interaction and Binding Efficiency of Tetracaine Hydrochloride (Anesthetic Drug) with Anionic Surfactants in the Presence of NaCl Solution Using Surface Tension and UV–Visible Spectroscopic Methods (2022)

Surfactants are ubiquitous materials that are used in diverse formulations of various products. For instance, they improve the formulation of gel by improving its wetting and rheological properties. Here, we describe the effects of anionic surfactants on an anesthetic drug, tetracaine hydrochloride (TCH), in NaCl solution with tensiometry and UV-visible techniques. Various micellar, interfacial, and thermodynamic parameters were estimated. The outputs were examined by using different theoretical models to attain a profound knowledge of drug-surfactant mixtures. The presence of attractive interactions among drug and surfactant monomers (synergism) in mixed micelle was inferred. However, it was found that sodium dodecyl sulfate (SDS) showed greater interactions with the drug in comparison to sodium lauryl sarcosine (SLS). The binding of the drug with surfactants was monitored with a spectroscopic technique (UV-visible spectra). The results of this study could help optimize the compositions of these mixed aggregates and find the synergism between monomers of different used amphiphiles.
Phosphazenes (2006)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.