gebhart/patrepeval huggingface dataset:
Analysis of dual-task elderly gait using wearable plantar-pressure insoles and accelerometer (2014)

Dual-task gait allows assessment of impaired executive function and mobility control in older individuals, which are risk factors of falls. This study investigated gait changes in older individuals due to the addition of a cognitive load, using wearable pressure-sensing insole and tri-axial accelerometer measures. These wearable sensors can be applied at the point-of-care. Eleven elderly (65 years or older) individuals walked 7.62 m with and without a verbal fluency cognitive load task while wearing FScan 3000E pressure-sensing insoles in both shoes and a Gulf Coast X16-1C tri-axial accelerometer at the pelvis. Plantar-pressure derived parameters included center of force (CoF) path and temporal measures. Acceleration derived measures were descriptive statistics, Fast Fourier Transform quartile, ratio of even-to-odd harmonics, and maximum Lyapunov exponent. Stride time, stance time, and swing time all significantly increased during dual-task compared to single-task walking. Minimum, mean, and median CoF stance velocity; cadence; and vertical, anterior-posterior, and medial-lateral harmonic ratio all significantly decreased during dual-task walking. Wearable plantar pressure-sensing insole and lower back accelerometer derived-measures can identify gait differences between single-task and dual-task walking in older individuals and could be used in point-of-care environments to assess for deficits in executive function and mobility impairments.
Self-assembling peptides as immunomodulatory biomaterials (2023)

Self-assembling peptides are a type of biomaterial rapidly emerging in the fields of biomedicine and material sciences due to their promise in biocompatibility and effectiveness at controlled release. These self-assembling peptides can form diverse nanostructures in response to molecular interactions, making them versatile materials. Once assembled, the peptides can mimic biological functions and provide a combinatorial delivery of therapeutics such as cytokines and drugs. These self-assembling peptides are showing success in biomedical settings yet face unique challenges that must be addressed to be widely applied in the clinic. Herein, we describe self-assembling peptides' characteristics and current applications in immunomodulatory therapeutics.
Let’s be sincere about eliminating systemic racism (2020)

I admit that I have many biases about different things, which are feelings and perceptions that result mainly from my early formative years. These mostly unconscious biases are deeply ingrained in me and are very difficult to change, but I make a conscious effort to successfully control and mitigate their effects by reading extensively, participating in training sessions, and engaging in deep introspection. These efforts are successful because I am truly sincere about my desire to eliminate, to the extent possible, these biases from my persona. I am not authentically unbiased, meaning I was not born and raised without biases, but I am truly sincere about changing my attitudes concerning my implicit or unconscious biases. Do people need to be authentically unbiased to fight against prejudice and racism, or is sincerity, accompanied by appropriate actions, enough? In my opinion, being sincere, managing your biases, and redirecting your actions accordingly can
The 2000 Olympic Games of protein structure prediction; fully automated programs are being evaluated vis-à-vis human teams in the protein structure prediction experiment CAFASP2 (2000)

In this commentary, we describe two new protein structure prediction experiments being run in parallel with the CASP experiment, which together may be regarded as the 2000 Olympic Games of structure prediction. The first new experiment is CAFASP, the Critical Assessment of Fully Automated Structure Prediction. In CAFASP, the participants are fully automated programs or Internet servers, and here the automated results of the programs are evaluated, without any human intervention. The second new experiment, named LiveBench, follows the CAFASP ideology in that it is aimed towards the evaluation of automatic servers only, while it runs on a large set of prediction targets and in a continuous fashion. Researchers will be watching the 2000 protein structure prediction Olympic Games, to be held in December, in order to learn about the advances in the classical 'human-plus-machine' CASP category, the fully automated CAFASP category, and the comparison between the two.
Fully coupled numerical analysis of high frequency induction heating and warm sheet metal forming (2015)

The present study aims to develop a warm forming process for an aluminum alloy sheet to reduce weight of an electric housing part. Considering that the target product is produced through a series of metal forming processes using a progressive die, high frequency induction heating is proposed to heat a specific drawing punch locally and rapidly, out of a series performed using a progressive die. To validate the effect of the induction heating on the formability improvement of aluminum alloys, a fully coupled numerical simulation is proposed: (i) finite element (FE) analyses for the multi‐stage deep drawing processes are performed to predict formability at each stage; (ii) electrostatic‐thermal coupled FE analysis is performed to predict the temperature rise of the drawing punch; and (iii) thermo‐mechanical coupled analysis is conducted to investigate the effect of induction heating on the formability change. Through the proposed coupled simulation, it is proven that the drawing punch can be efficiently heated without a significant increase in cycle time, and the corresponding drawing process using aluminum alloys can be successfully performed without forming failure.
Front Cover: Cell‐Free Protein Synthesis in Bifunctional Hyaluronan Microgels: A Strategy for In Situ Immobilization and Purification of His‐Tagged Proteins (ChemSystemsChem 3/2020) (2020)

The Front Cover is provided by the Thiele group at Leibniz IPF Dresden (Germany). The image shows a microgel hosting cell-free synthesis of green fluorescent protein. Despite its open, membrane-free nature, the multifunctional microgel is also able to trap proteins inside its polymer matrix. More information can be found in the Article by J. Thiele and co-workers.
Impacts of Next-Generation Concepts of Military Operations on Human Effectiveness (2001)

Innovations in information technology have revolutionized business practices over the past decade. Commensurate changes in military practices have been much slower in coming. There now appears to be broad agreement, however, that a revolution in military affairs may be at hand. This article reviews these overall trends and their implications for military operations, particularly in terms of likely impacts on human effectiveness in general, and human decision making in particular.
Band widths and gaps from the Tran-Blaha functional: Comparison with many-body perturbation theory (2013)

For a set of ten crystalline materials (oxides and semiconductors), we compute the electronic band structures using the Tran-Blaha [Phys. Rev. Lett. 102, 226401 (2009)] (TB09) functional. The band widths and gaps are compared with those from the local-density approximation (LDA) functional, many-body perturbation theory (MBPT), and experiments. At the density-functional theory (DFT) level, TB09 leads to band gaps in much better agreement with experiments than LDA. However, we observe that it globally underestimates, often strongly, the valence (and conduction) band widths (more than LDA). MBPT corrections are calculated starting from both LDA and TB09 eigenenergies and wave functions. They lead to a much better agreement with experimental data for band widths. The band gaps obtained starting from TB09 are close to those from quasiparticle self-consistent $GW$ calculations, at a much reduced cost. Finally, we explore the possibility to tune one of the semiempirical parameters of the TB09 functional in order to obtain simultaneously better band gaps and widths. We find that these requirements are conflicting.
Excitons in a II-VI semiconductor microcavity in the strong-coupling regime (1995)

Microcavities which contain Zn-Cd-Se quantum wells as the resonant medium have been fabricated and tested at blue-green wavelengths. We see clear evidence of coupled-mode behavior at the n=1 heavy-hole exciton in both angle and temperature tuning experiments, with anticrossing (vacuum-Rabi) splittings approaching 20 meV. The exciton-cavity interaction is consistent with predictions by theory in the strong-coupling regime, and illustrates the impact of the large oscillator strength available in II-VI compounds.
Incorporating Model-Specific Score Distribution in Speaker Verification Systems (2008)

<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> It has been shown that the authentication performance of a biometric system is dependent on the models/templates specific to a user. As a result, some users may be more easily recognized or impersonated than others. The various categories of users have been characterized by Doddington <etal/> (1988). We refer to this unbalanced performance across users as the Doddington's zoo effect. In the context of fusion, we argue that this effect is system-dependent, i.e., a user model that is easily impersonated (a lamb) in one system may be easily recognized in another system (a sheep). While in principle, a fusion system could be trained to cope with the changing animal behavior of users from system to system, the lack of training data makes it impossible. We believe that one major cause of the Doddington's zoo effect is the variation of class conditional scores from one speaker model to another. We propose a two-level fusion framework that effectively realizes a fusion classifier adapted to each user. First, one applies a <emphasis emphasistype="boldital">client-specific</emphasis> (or model-specific) score normalization procedure to each of the system outputs to be combined. Then, one feeds the resulting normalized outputs to a fusion classifier (common to all users) as input to obtain a final combined score. Two existing model-specific score normalization procedures are considered in this framework, i.e., F- and Z-norms. In addition to them, a novel score normalization method called model-specific log-likelihood ratio (MS-LLR) is also proposed. While Z-norm is impostor-centric, i.e., it makes use of only the impostor score statistics, F-norm and the proposed MS-LLR are client-impostor centric, i.e., they consider both the client and impostor score statistics simultaneously. Our findings based on the XM2VTS and the NIST2005 databases show that when client-impostor centric normalization procedures are used to implement the proposed two-level fusion framework, the res</para>
Synthesis and physiological properties of some heterocyclic‐aromatic sulphides and sulphones. I. Synthesis of some aryl‐pyridyl sulphides (1961)

Abstract The preparation of some aryl‐pyridyl sulphides with potential acaricidal properties is described. In the compounds synthesized the benzene nucleus is substituted with a para ‐chlorine atom or with three chlorine atoms in positions 2, 4 and 5. Position 5 in the pyridine nucleus is either unsubstituted or carries a chlorine substituent. From a few aryl‐pyridyl sulphides the corresponding N‐oxides have been prepared.
Über Fluoromethoxoborate (1968)

Abstract Es wird über Darstellung und Eigenschaften von Fluoromethoxoboraten M[BF n (OCH 3 ) 4‐n ] (M = Na, K; n = 1, 2, 3) berichtet. Die thermische Zersetzung dieser Fluoroborate verläuft bei n = 1 unter Bildung von Fluorid und Borsäureester, bei den fluorreicheren Verbindungen bildet sich Fluorid, Tetrafluoroborat und Borsäureester. Die als Zwischenverbindungen auftretenden Fluoroborsäureester sind nur in Spuren im flüchtigen Zersetzungsprodukt enthalten.
Testing Changes in Communities for the Stochastic Block Model (2018)

We propose and analyze the problems of \textit{community goodness-of-fit and two-sample testing} for stochastic block models (SBM), where changes arise due to modification in community memberships of nodes. Motivated by practical applications, we consider the challenging sparse regime, where expected node degrees are constant, and the inter-community mean degree ($b$) scales proportionally to intra-community mean degree ($a$). Prior work has sharply characterized partial or full community recovery in terms of a "signal-to-noise ratio" ($\mathrm{SNR}$) based on $a$ and $b$. For both problems, we propose computationally-efficient tests that can succeed far beyond the regime where recovery of community membership is even possible. Overall, for large changes, $s \gg \sqrt{n}$, we need only $\mathrm{SNR}= O(1)$ whereas a naïve test based on community recovery with $O(s)$ errors requires $\mathrm{SNR}= Θ(\log n)$. Conversely, in the small change regime, $s \ll \sqrt{n}$, via an information-theoretic lower bound, we show that, surprisingly, no algorithm can do better than the naïve algorithm that first estimates the community up to $O(s)$ errors and then detects changes. We validate these phenomena numerically on SBMs and on real-world datasets as well as Markov Random Fields where we only observe node data rather than the existence of links.
ATP-Binding Cassette Transporters, Atherosclerosis, and Inflammation (2014)

Although recent genome-wide association studies have called into question the causal relationship between high-density lipoprotein (HDL) cholesterol levels and cardiovascular disease, ongoing research in animals and cells has produced increasing evidence that cholesterol efflux pathways mediated by ATP-binding cassette (ABC) transporters and HDL suppress atherosclerosis. These differing perspectives may be reconciled by a modified HDL theory that emphasizes the antiatherogenic role of cholesterol flux pathways, initiated in cells by ABC transporters. ABCA1 and ABCG1 control the proliferation of hematopoietic stem and multipotential progenitor cells in the bone marrow and hematopoietic stem and multipotential progenitor cell mobilization and extramedullary hematopoiesis in the spleen. Thus, activation of cholesterol efflux pathways by HDL infusions or liver X receptor activation results in suppression of hematopoietic stem and multipotential progenitor cell mobilization and extramedullary hematopoiesis, leading to decreased production of monocytes and neutrophils and suppression of atherosclerosis. In addition, macrophage-specific knockout of transporters has confirmed their role in suppression of inflammatory responses in the arterial wall. Recent studies have also shown that ABCG4, a close relative of ABCG1, controls platelet production, atherosclerosis, and thrombosis. ABCG4 is highly expressed in megakaryocyte progenitors, where it promotes cholesterol efflux to HDL and controls the proliferative responses to thrombopoietin. Reconstituted HDL infusions act in an ABCG4-dependent fashion to limit hypercholesterolemia-driven excessive platelet production, thrombosis, and atherogenesis, as occurs in human myeloproliferative syndromes. Activation of ABC transporter-dependent cholesterol efflux pathways in macrophages, hematopoietic stem and multipotential progenitor cells, or platelet progenitors by reconstituted HDL infusion or liver X receptor activation remain promising approaches to the treatment of human atherothrombotic diseases.
Nmr studies on the presence of domain structures in polysaccharides (1987)

Abstract A variety of nmr transient techniques demonstrate the absence of domain structures in powders of α‐ and β‐cyclodextrins, dextran B512F, and their “deuterated” analogs where deuterium replaces exchangeable protons. Cyclodextrins and dextran are inferred to be homogeneously ordered and disordered one‐phase systems, respectively. We show how erroneous results concerning the presence and sizes of rigid and mobile domains can be reached from the interpretations of two‐component free induction decays and spin–lattice relaxation behavior of polysaccharides. In our approach, we have measured 1 H free induction decays and lineshapes, and 1 H spin–lattice and dipolar relaxation times, in addition to using Goldman–Shen experiments and 13 C cross‐polarization magic‐angel sample spinning. Self‐consistent nmr results are suggested as essential means to corroborate conclusions concerning domain structures in biopolymers.
Synchronous Occurrence of Chronic Myeloid Leukemia and Mantle Cell Lymphoma (2017)

Chronic myeloid leukemia (CML) and mantle cell lymphoma (MCL) are hematologic malignancies that originate from different oligopotent progenitor stem cells, namely, common myeloid and lymphoid progenitor cells, respectively. Although blastic transformation of CML can occur in the lymphoid lineage and CML has been related to non-Hodgkin lymphoma on transformation, to our knowledge, de novo and synchronous occurrence of CML and MCL has not been reported. Herein, we report the first case of synchronous CML and MCL in an otherwise healthy 38-year-old man. Potential etiologies and pathological relationships between the two malignancies are explored, including the possibility that the downstream effects of BCR-ABL may link it to an overexpression of cyclin D1, which is inherent to the etiology of MCL.
Isolation and partial characterization of the entire human proα I(II) collagen gene (1985)

Using a cDNA probe specific for the bovine Type II procollagen, a series of overlapping genomic clones containing 45 kb of contiguous human DNA have been isolated. Sequencing of a 54 bp exon, number 29, provided direct evidence that the recombinant clones bear human Type II collagen sequences. Localization of the 5' and 3' ends of the gene indicated that the human Type II collagen gene is 30 kb in size. This value is significantly higher than that of the homologous avian gene. The segregation of a polymorphic restriction site in informative families conclusively demonstrated that the Type II gene is found in a single copy in the human haploid genome. Finally, sequencing of a triple helical domain exon has confirmed that a rearrangement leading to the fusion of two exons occurred in the pro alpha 1(I) gene, following the divergence of the fibrillar collagens.
Computational analysis of electric field distribution in dual-layered phase-change disc (2003)

We developed a Finite-Difference Time Domain (FDTD) Method based simulator that can analyze Dual-Layered phase-change disc structure. Because of a substrate thickness error, it is necessary to consider spherical aberration. The electric field distributions have been calcuated on Single-Layered and Dual-Layered phase-change discs. We found differences between the electic distributions focused on a groove and on a land. These calculation results can explain the corresponding experimental results clearly.
Soil Bulk Density Analysis in Three Dimensions by Computed Tomographic Scanning (1982)

Abstract Current soil bulk densitometric techniques lack the precision to detect three‐dimensional changes in density in a nondestructive manner. The x‐ray transmission computed tomography (CT) scanner was evaluated as a tool to determine soil bulk density. This scanner is an advanced tool in diagnostic radiology used to obtain a nondestructive cross‐sectional representation of the human body. Typical accuracy and precision for CT scanners are known for materials like human tissue with a linear attenuation coefficient near water. Machine response was evaluated near the upper limit of the measurement range where denser materials, such as soil, are located. Scanner analyses of soil and glass bead‐air filled sphere samples that varied in bulk density from 0.14 to 1.64 g/cm 3 revealed that a positive linear response occurred with increasing density. For the Metea sandy loam soil (Arenic Hapludalfs), this CT scanner was found to have precision in the order of 19 mg/cm 3 . Spatial resolution or the ability to distinguish between two objects in the scanning plane was found to range from 1.25 by 1.25 by 2 mm 3 to 6.4 mm in diameter by 2 mm. The greater resolution was obtained when density within the sample varied greatly. Errors in data can occur as a result of certain machine artifacts; however, many of these can be avoided by relatively simple methods. It was concluded that the CT scanner can be used to determine soil bulk density with good three‐dimensional spatial resolution. This is a potentially promising tool for research in the areas of compaction, soil management, and cultivation.
Fast Evaluation of 69 Basal Cell Carcinomas With Ex Vivo Fluorescence Confocal Microscopy (2013)

We herein propose, describe, and validate FCM criteria for BCC diagnosis. Fluorescence confocal microscopy is an attractive alternative to histopathologic analysis of frozen sections during Mohs surgery because large areas of freshly excised tissue can be assessed in real time without the need for tissue processing while minimizing labor and costs.
Reversing the collision-avoidance handshake in wireless networks (1999)

Article Free Access Share on Reversing the collision-avoidance handshake in wireless networks Authors: J. J. Garcia-Luna-Aceves Computer Engineering Department, Baskin School of Engineering, University of California, Santa Cruz, California Computer Engineering Department, Baskin School of Engineering, University of California, Santa Cruz, CaliforniaView Profile , Asimakis Tzamaloukas Computer Engineering Department, Baskin School of Engineering, University of California, Santa Cruz, California Computer Engineering Department, Baskin School of Engineering, University of California, Santa Cruz, CaliforniaView Profile Authors Info & Claims MobiCom '99: Proceedings of the 5th annual ACM/IEEE international conference on Mobile computing and networkingAugust 1999 Pages 120–131https://doi.org/10.1145/313451.313516Online:01 August 1999Publication History 37citation589DownloadsMetricsTotal Citations37Total Downloads589Last 12 Months12Last 6 weeks9 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Generation of tailored subsurface zones in steels containing metastable austenite by adaptive machining and validation by eddy current testing (2020)

Abstract In order to withstand high mechanical and tribological loads, it is important that the components not only have a high core ductility but also a hard surface. Typically, a suitable microstructure is created by heat treatment processes before the workpiece is machined. However, these processes are time and energy consuming and can lead to component distortion. It would therefore be of great advantage if no additional heat treatment process would be required to produce a hardened subsurface zone. Since turning is often already integrated as a machining process in production lines, it would be advantageous to create a hardened subsurface within this process. As there is no possibility to measure the hardness directly during the turning process, a soft sensor was developed to determine the properties of the subsurface directly during the machining process. Steels with metastable austenite are of particular interest in this context, as metastable austenite can be converted into martensite by deformation. The amount of martensite produced in the subsurface can be adjusted provided that suitable turning parameters can be found. For this purpose, a process parallel material removal simulation was used to determine the actual conditions governing the process. It was found that there is a correlation between the martensite content and the amplitude of the 3 rd harmonic of eddy current testing. Therefore, an eddy current sensor accompanying the process can be used as a basis for controlling the turning process for tailored martensite volume content adjustment.