gebhart/patrepeval huggingface dataset:
Human tissue adrenergic receptors are not predictive of responses to epinephrine in vivo (1989)

To test the hypotheses that adrenergic receptor and adenylate cyclase characteristics of easily accessible circulating cells reflect those of relatively inaccessible extravascular catecholamine target tissues in a subtype-specific fashion and that these characteristics predict responses to catecholamines in vivo, we studied 22 normal humans. Adrenergic receptors and their linked adenylate cyclase systems were measured in mononuclear leukocytes (MNL; beta 2), platelets (alpha 2), skeletal muscle membranes (beta 2), and fat cells (B1 and alpha 2) and compared with the responses to stepped, intravenous epinephrine infusions in vivo. MNL beta 2-adrenergic receptor densities (but not antagonist affinities) were correlated (r = 0.627; P less than 0.01) with skeletal muscle beta 2-adrenergic densities. However, other adrenergic receptor characteristics and basal and maximally stimulated adenosine 3',5'-cyclic monophosphate (cAMP) contents of MNL and all adrenergic receptor characteristics and cAMP contents of platelets were unrelated to the corresponding measurements in skeletal muscle and fat. Furthermore, there were no consistent relationships between tissue adrenergic receptor-adenylate cyclase characteristics and the chronotropic, diastolic depressor, lipolytic, ketogenic, glycemic, or glycogenolytic-glycolytic responses to epinephrine in vivo. Thus the data support the hypothesis that adrenergic receptor densities on circulating cells reflect those of extravascular target tissues in a subtype-specific fashion. On the other hand, the data do not support the hypothesis that physiological interindividual variation of adrenergic receptor characteristics is of sufficient magnitude to alter sensitivity to epinephrine in vivo.
Quinine improves the results of intensive chemotherapy in myelodysplastic syndromes expressing P glycoprotein: results of a randomized study. (2006)

We designed a randomized trial of IC with or without quinine, an agent capable of reverting the multidrug resistance (mdr) phenotype, in patients aged < or = 65 years with high risk MDS. Patients were randomized to receive Mitoxantrone 12 mg/m2/d d2-5 + AraC 1 g/m2/12 h d1-5, with (Q+) or without (Q-) quinine (30 mg/kg/day). 131 patients were included. PGP expression analysis was successfully made in 91 patients and 42 patients (46%) had positive PGP expression. In PGP positive cases, 13 of the 25 (52%) patients who received quinine achieved CR, as compared to 3 of the 17 (18%) patients treated with chemotherapy alone (p = 0.02). In PGP negative cases, the CR rate was 35% and 49%, respectively in patients who received quinine or chemotherapy alone (difference not significant). In the 42 PGP positive patients, median Kaplan-Meier (KM) survival was 13 months in patients allocated to the quinine group, and 8 months in patients treated with chemotherapy alone (p = 0.01). In PGP negative patients, median KM survival was 14 months in patients allocated to the quinine group, and 14 months in patients treated with chemotherapy alone. Side effects of quinine mainly included vertigo and tinnitus that generally disappeared with dose reduction. Mucositis was significantly more frequently observed in the quinine group. No life threatening cardiac toxicity was observed. In conclusion, results of this randomized study show that quinine increases the CR rate and survival in PGP positive MDS cases treated with IC. The fact that quinine had no effect on the response rate and survival of PGP negative MDS suggests a specific effect on PGP mediated drug resistance rather than, for instance, a simple effect on the metabolism of Mitoxantrone and/or AraC.
Etude des protocoles de découverte de service dans le cadre des réseaux adhoc (2007)

This document present the state of the art regarding Service Discovery protocols in general in a first part. The second part show how they can fit within the frame of adhoc networks
Perspectivas teóricas y modelos interpretativos para el estudio del síndrome de quemarse por el trabajo (1999)

"En este estudio se justifica la necesidad de estudiarel síndrome de quemarse por el trabajo. Desde unaperspectiva psicosocial, el síndrome de quemarse se conceptualizacomo un proceso en el que intervienen elementoscognitivo-aptitudinales (baja realización personal en eltrabajo), emocionales (agotamiento emocional) y actitudinales(despersonalización). Con base en esta conceptualizaciónse presenta una taxonomía que integra diferentes modeloselaborados para explicar la etiología y consecuenciasdel síndrome (modelos explicativos). En esta taxonomía sedistingue un primer grupo de modelos desarrollados en elmarco de la teoría sociocognitiva del yo, un segundo grupode modelos elaborados desde las teorías del intercambiosocial y finalmente se considera un tercer grupo de modeloselaborados desde la teoría organizacional. El trabajoconcluye con la presentación de los estudios realizados pornuestro equipo de investigación y sugerencias de cara a estudiosfuturos."
Surface thermodynamic properties of synthetic hydrotalcite compounds (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSurface thermodynamic properties of synthetic hydrotalcite compoundsZ. Li, R. F. Giese, and C. J. van OssCite this: Langmuir 1994, 10, 1, 330–333Publication Date (Print):January 1, 1994Publication History Published online1 May 2002Published inissue 1 January 1994https://pubs.acs.org/doi/10.1021/la00013a049https://doi.org/10.1021/la00013a049research-articleACS PublicationsRequest reuse permissionsArticle Views257Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A Highly Available Software Defined Fabric (2014)

Existing SDNs rely on a collection of intricate, mutually-dependent mechanisms to implement a logically centralized control plane. These cyclical dependencies and lack of clean separation of concerns can impact the availability of SDNs, such that a handful of link failures could render entire portions of an SDN non-functional. This paper shows why and when this could happen, and makes the case for taking a fresh look at architecting SDNs for robustness to faults from the ground up. Our approach carefully synthesizes various key distributed systems ideas -- in particular, reliable flooding, global snapshots, and replicated controllers. We argue informally that it can offer high availability in the face of a variety of network failures, but much work needs to be done to make our approach scalable and general. Thus, our paper represents a starting point for a broader discussion on approaches for building highly available SDNs.
Evidence of Correlation between Catalyst Particles and the Single-Wall Carbon Nanotube Diameter: A First Step towards Chirality Control (2012)

Controlling the structure of single-wall carbon nanotubes during their synthesis by chemical vapor deposition remains a challenging issue. Here, using a specific synthesis protocol and ex situ transmission electron microscopy, we perform a statistical analysis of the structure of the tubes and of the catalyst particles from which they grow. We discriminate two nucleation modes, corresponding to different nanotube-particle junctions, that occur independently of the particle size. With the support of tight binding calculations, we show that a direct control of the nanotube diameter by the particle can only be achieved under growth conditions close to thermodynamic equilibrium.
Tangible user interfaces: Tools to examine, assess, and treat dynamic constructional processes in children with developmental coordination disorders (2006)

Article Tangible user interfaces: Tools to examine, assess, and treat dynamic constructional processes in children with developmental coordination disorders was published on July 1, 2006 in the journal International Journal on Disability and Human Development (volume 5, issue 3).
The ensemble Kalman filter and its relations to other nonlinear filters (2015)

The Ensemble Kalman filter (EnKF) is a standard algorithm in oceanography and meteorology, where it has got thousands of citations. It is in these communities appreciated since it scales much better with state dimension n than the standard Kalman filter (KF). In short, the EnKF propagates ensembles with N state realizations instead of mean values and covariance matrices and thereby avoids the computational and storage burden of working on n × n matrices. Perhaps surprising, very little attention has been devoted to the EnKF in the signal processing community. In an attempt to change this, we present the EnKF in a Kalman filtering context. Furthermore, its application to nonlinear problems is compared to sigma point Kalman ilters and the particle ilter, so as to reveal new insights and improvements for high-dimensional filtering algorithms in general. A simulation example shows the EnKF performance in a space debris tracking application.
A Psychophysical Experiment Evaluating the Color Accuracy of Several Multispectral Image Capture Techniques. (2003)

A paired comparison psychophysical experiment was performed to evaluate the quality of several imaging techniques. Images rendered for an LCD were compared with twoand three-dimensional objects viewed in a multisource light booth. The test images were a combination of different spectral capture and image reconstruction techniques estimating spectral reflectance factor transformed into colorimetric images by imposing an illuminant and observer, in this case simulated daylight (6800K) and incandescent (2700K) for the 1931 CIE observer. Some images were also transformed directly to colorimetry. To compare the color accuracy with conventional RGB imaging, color-managed images from a typical consumer camera were included in the experiment. All image types captured using the research-grade camera performed very well, regardless of the illuminant, number of channels, or transformation method. A set of colorimetric images captured using previously optimized filters performed as well as the multispectral images. The commercial-grade images proved to be inferior to those created with the research-grade system, as expected.
Planar UWB phase shifter using parallel coupled lines combined with short-ended stubs and impedance transformer (2015)

An ultra-wideband (UWB) phase shifter with wide range of differential phase shift is proposed. To achieve this performance, the design uses quarter wavelength parallel coupled lines combined with short-ended stub structure and an impedance transformer. The value of the differential phase can be adjusted through varying the coupling coefficient of the coupled lines along with the length and impedance of the short-ended stubs and transformer. The theory of operation for the proposed designs is explained. To validate the theory, two phase shifters are designed to realize 90° and 180° differential phase across the band 3.1-10.6 GHz with less than ±11° differential phase imbalance and less than 1.2 dB insertion loss.
Combined script and page orientation estimation using the Tesseract OCR engine (2009)

This paper proposes a simple but effective algorithm to estimate the script and dominant page orientation of the text contained in an image. A candidate set of shape classes for each script is generated using synthetically rendered text and used to train a fast shape classifier. At run time, the classifier is applied independently to connected components in the image for each possible orientation of the component, and the accumulated confidence scores are used to determine the best estimate of page orientation and script. Results demonstrate the effectiveness of the approach on a dataset of 1846 documents containing a diverse set of images in 14 scripts and any of four possible page orientations.A C++ implementation of this work will be made available in a future release of the open-source Tesseract OCR engine [1].
CLINICAL COMPARISON OF CHEMICAL PEELING, DERMABRASION, AND 5-FU FOR SENILE KERATOSES (1970)

SPIRA, MELVIN M.D.; FREEMAN, ROBERT M.D.; ARFAI, PARVIZ M.D.; GEROW, FRANK J. M.D.; HARDY, BARON S. M.D. Author Information
Data for Heuristic Optimization of Electric Vehicles’ Charging Configuration Based on Loading Parameters (2020)

This dataset includes multiple files related to optimization of electric vehicles to minimize overloading in low voltage grids by varying the locations available to charge the EVs. The data include lognormally sampled hourly sorted scenarios across 11 charging locations for a stochastics-based Monte Carlo simulation. This simulation runs through 2 million scenarios based on actual probabilities to incorporate most possible situations. It also includes samples from normally distributed household electricity use scenarios based on agent-based modeling. The article includes the test grid parameters for simulation, which were used to create a benchmark grid in DigSilent Powerfactory software, as well as intermediate outputs defining worst case scenarios when electric vehicles were charged and results from three different optimization approaches involving a reduction in voltage drops, cable overloading and total line losses. The outputs from the benchmark grid were used to train a machine learning algorithm, the weights and codes for which are also attached. This trained network acted as the grid for subsequent iterative optimization procedures. Outputs are presented as a comparison between pre-optimization and post-optimization scenarios. The above dataset and procedure were repeated while varying the number of EVs between 0 and 100 in increments of 20, data for which are also attached. The data article supports a related submission titled “Minimization of Overloading Caused by Electric Vehicle (EV) Charging in Low Voltage Networks”.
An approach for utilizing known terrain and land feature data in estimation of the clutter covariance matrix (2002)

The secondary data for estimation of the clutter covariance matrix in space-time adaptive processing (STAP) is normally obtained from range rings in the vicinity of the test range ring. The assumption is that near-by range rings are representative. However, this is not always true. A clutter model is developed and the condition necessary for obtaining a good estimate of the clutter covariance matrix are discussed. A theoretical basis for choosing reference rings which contain clutter patches that are equivalent to one or two patches within the test range ring is provided. A proposal for using a priori map data to classify clutter patches based upon the type of features contained within them is presented. It is conjectured that patches with equivalent classifications will have representative radar returns. An application to post Doppler radar processing is presented.
(Invited) Tunnel-Barrier Rectifiers for Optical Nantennas (2016)

We present comprehensive experimental and theoretical work on tunnel-barrier rectifiers comprising double (Nb 2 O 5 -Al 2 O 3 ) and triple (Ta 2 O 5 -Nb 2 O 5 -Al 2 O 3 ) insulator configurations engineered to enhance low-voltage nonlinearity. The key rectifier properties, asymmetry, nonlinearity and responsivity have been assessed from current-voltage measurements. A superior low-voltage asymmetry (12 at 0.1 V) and responsivity (5 A/W at 0.2 V) for MIIIM rectifiers have been observed. The results demonstrate enhanced rectification by atomically multi-layering tunnel barriers in cascaded and non-cascaded MIIIM arrangements, for inclusion in optical nantennas.
Characterization of factors mediating oviposition site choice by Culex tarsalis. (1995)

Fermented infusions of organic matter were tested for their effects on Culex tarsalis oviposition. Bermuda grass infusion and polluted water collected from a natural oviposition site (La Brea tar pits, CA) enhanced oviposition rates, but an alfalfa infusion and water from a 2nd natural oviposition site (Prado Basin, CA) did not. Bermuda grass infusion was fractionated by dialysis and filter sterilization. Crude Bermuda grass infusion, and fractions of the infusion containing large molecules (> 12,000 daltons), particulates, and microorganisms significantly increased oviposition rates compared to distilled water controls. The fraction containing small molecules was no better than a distilled water control, suggesting that small molecules are not involved in oviposition stimulation in this species. However, using the egg raft counting bioassay, the possibility that the small molecules fraction contained oviposition attractants could not be ruled out. Overall, our experiments suggest that results obtained with the egg raft counting bioassay, which has been used frequently to screen for oviposition attractants, should be interpreted with caution. High oviposition rates in this bioassay may be due to responses to factors such as nonvolatile, contact oviposition stimulants rather than to volatile attractants.
Molecular model of the cyclic GMP-binding domain of the cyclic GMP-gated ion channel (1992)

The structure of the cyclic GMP-binding domain of the cyclic GMP-gated ion channel from bovine retinal rod photoreceptors has been modeled by analogy to the crystal structure of the homologous cyclic AMP-binding domain of catabolite gene activator protein (CAP). The modeled cyclic GMP-binding domain has a three-residue deletion and a five-residue insertion between beta strands compared to CAP. The major interactions of the ion channel with cyclic GMP are similar to those observed for cyclic AMP bound to CAP and predicted for cGMP bound to the cGMP-dependent protein kinase: Gly 543 and Glu 544 make hydrogen-bond interactions with the ribose 2'-OH, Arg 559 forms an ion pair with the charged phosphate oxygen, and Thr 560 forms hydrogen-bond interactions with an exocyclic phosphate oxygen and with the 2-amino group of cGMP. Three additional potential interactions were predicted from the model structure. Ile 545 O and Ser 546 OH form hydrogen-bond interactions with an exocyclic phosphate oxygen, and Phe 533 may interact with the aromatic ring of cGMP. This model is in agreement with both the analogue binding experiments and the mutational analysis of Thr 560.
Adaptive document layout (2004)

How to automatically reformat, resize, and paginate electronic text and graphics so documents look as good on displays of any size as they do on paper.
ShapeMate: A virtual Tape Measure (2013)

We introduce ShapeMate, a framework for human body shape estimation and classification for on-line fashion applications. Given a single image of a subject our framework is able to simultaneously estimate detailed 3D human body shape and compute foreground segmentation with minimal user input. Once the body shape has been estimated, various semantic parameters are extracted for garment size and style recommendation. Preliminary results demonstrate that a single image holds enough information for accurate shape classification.
Differential usage of the CXC chemokine receptors 1 and 2 by interleukin‐8, granulocyte chemotactic protein‐2 and epithelial‐cell‐derived neutrophil attractant‐78 (1998)

The inflammatory response is mediated by a family of chemotactic cytokines, designated chemokines. The receptor usage of the CXC chemokine granulocyte chemotactic protein-2 (GCP-2) was compared with that of interleukin-8 (IL-8) and epithelial-cell-derived neutrophil attractant-78 (ENA-78). Chemokine activities were evaluated by measurement of intracellular calcium increase and by chemotaxis and binding assays, using CXC chemokine receptor (CXCR)-transfected cell lines. GCP-2 was equally potent at inducing a rise in [Ca2+]i in both CXCR1-transfected and CXCR2-transfected cells (minimal effective concentration 3 nM). IL-8 augmented the [Ca2+]i more efficiently in CXCR1-transfectants than in CXCR2-transfectants, whereas for ENA-78, threefold higher concentrations were necessary to obtain a calcium response in CXCR1-transfected cells than in CXCR2-transfectants. GCP-2 desensitized the calcium increase induced by IL-8 in both CXCR1-transfected and CXCR2-transfected cells, but ENA-78 only affected the IL-8-induced calcium response in CXCR2-transfectants. The half-maximal effective concentrations for migration of CXCR2-transfectants in response to GCP-2 and ENA-78 were similar (0.1 nM), whereas GCP-2 was tenfold more potent than ENA-78 on CXCR1-transfectants. Half-maximal migration of CXCR1-transfected and CXCR2-transfected cells was obtained with IL-8 at concentrations of no more than 0.01 nM. Radiolabeled IL-8 could efficiently be displaced from CXCR2 by IL-8, GCP-2 and ENA-78. In contrast, only IL-8 and GCP-2 but not ENA-78, competed for 125I-IL-8 binding to CXCR1. From these data, it can be concluded that, in addition to IL-8, GCP-2, but not ENA-78, efficiently binds to both CXCR1 and CXCR2. The differential receptor usage of the structurally related ELR+ CXC chemokines GCP-2 and ENA-78 is indicative of a different role in inflammatory reactions.
Polar Transmembrane-based Amino Acids in Presenilin 1 Are Involved in Endoplasmic Reticulum Localization, Pen2 Protein Binding, and γ-Secretase Complex Stabilization (2011)

γ-Secretase is composed of the four membrane proteins presenilin, nicastrin, Pen2, and Aph1. These four proteins assemble in a coordinated and regulated manner into a high molecular weight complex. The subunits constitute a total of 19 transmembrane domains (TMD), with many carrying important amino acids involved in catalytic activity, interaction with other subunits, or in ER retention/retrieval of unassembled subunits. We here focus on TMD4 of presenilin 1 (PS1) and show that a number of polar amino acids are critical for γ-secretase assembly and function. An asparagine, a threonine, and an aspartate form a polar interface important for endoplasmic reticulum retention/retrieval. A single asparagine in TMD4 of PS1 is involved in a protein-protein interaction by binding to another asparagine in Pen2. Intriguingly, a charged aspartate in TMD4 is critical for γ-secretase activity, most likely by stabilizing the newly formed complex.
Zero Autocorrelation Waveforms: A Doppler Statistic and Multifunction Problems (2006)

Constant amplitude zero autocorrelation (off the dc component) waveforms are constructed. These are called CAZAC waveforms. In the d-dimensional case they consist of N vectors, where N is given, and N is generally greater than d. The constructions are algebraic and have been implemented in user friendly software. They have the added feature that they are a spanning set for all d-dimensional signals. As such, and for N large, they are numerically stable in the presence of machine imperfections and they give good signal reconstruction in the presence of various noises. The one dimensional case provides effective thresholding to compute Doppler shifts