gebhart/patrepeval huggingface dataset:
100 Suns and the Nuclear Sublime (2005)

Essay| August 01 2005 100 Suns and the Nuclear Sublime: An Interview With Michael Light Robert Hirsch Robert Hirsch Robert Hirsch is the author of Exploring Color Photography: From the Darkroom to the Digital Studio; Seizing the Light: A History of Photography; and Photographic Possibilities: The Expressive Use of Ideas, Materials & Processes, Second Edition. Hirsch’s latest installation, Manifest Destiny: Dreaming the American West is on view at CEPA Gallery in Buffalo, NY through September 5, 2005. Search for other works by this author on: This Site PubMed Google Scholar Afterimage (2005) 33 (1): 24–29. https://doi.org/10.1525/aft.2005.33.1.24 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Robert Hirsch; 100 Suns and the Nuclear Sublime: An Interview With Michael Light. Afterimage 1 August 2005; 33 (1): 24–29. doi: https://doi.org/10.1525/aft.2005.33.1.24 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAfterimage Search This content is only available via PDF. © 2005 by The Regents of the University of California2005 Article PDF first page preview Close Modal You do not currently have access to this content.
Analysis of the probability density of the detection signal in an optical coherent system from measurement results using DFB laser diodes (1995)

Abstract This article presents the analysis of the probability density of the envelope of the intermediate‐frequency signal in an optical coherent system. The electrical components were replaced by idealized numerical models, in order to be able to compare the results with theoretical results from the literature. The results from this work agree well with numerical calculations. A numerical simulation will be given in this article. The results make it possible to give much better statements about the statistical properties of laser phase noise. © 1995 John Wiley &amp; Sons, Inc.
Clocking and circuit design for a parallel I/O on a first-generation CELL processor (2005)

A parallel I/O is integrated on a first-generation CELL processor in 90nm SOI CMOS. A clock-tracking architecture suppresses reference jitter to achieve 6.4Gbit/s/link operation at 21.6mW/Gbit/s. SOI effects on analog circuits, in particular high-speed receivers, are addressed to achieve a receiver sensitivity of /spl plusmn/12mV at 6.4Gbit/s with BER <10/sup -14/ measured using 7b PRBS data.
Influence of Pyrolysis Operating Conditions on Bio-Oil Components: A Microscale Study in a Pyroprobe (2011)

A fast pyrolysis process has emerged as one of the techniques to produce transportation fuels using various biomass types that are regionally important. It is well understood that high heating rates, very small particles with low mass transfer limitations, and moderate operating temperatures are essential for obtaining high yield of liquid from the fast pyrolysis process. However, how the heating rates and operating temperatures would influence individual compounds in the liquid obtained from the fast pyrolysis process has not been studied in detail. Therefore, a microscale pyrolysis study was performed by changing different parameters (biomass type, filament heating rate, and final pyrolysis temperature) to understand the influence of these operating parameters on each compound formed during the process. Two biomass types (pine wood and switchgrass) were selected for this study: (i) pine wood was selected because of its availability in the southeastern region of the United States, and (ii) switchgrass was chosen because it has been identified as one of the bioenergy crops in the United States. Pyrolysis temperatures were changed from 450 to 750 °C in increments of 50 °C, whereas the heating rates selected were 50, 100, 500, 1000, and 2000 °C/s. Twenty-eight bio-oil compounds were quantified in each experimental condition. This study found that phenols and toluene concentrations increased with the increase in pyrolysis temperature irrespective to the biomass type. On the other hand, the change in the yield of ketones, furans, and guaiacols with the change in pyrolysis temperature depended on the type of biomass. The effect of filament heating rate on bio-oil yield was not statistically significant because the biomass heating rate was almost constant irrespective of different filament heating rates.
Supplemental tables and legend from Transplantation of iPS-Derived Tumor Cells with a Homozygous MHC Haplotype Induces GRP94 Antibody Production in MHC-Matched Macaques (2023)

&lt;p&gt;Table S1: Virus vectors used in the present study, Table S2: Primer sets for RT-PCR, Table S3: List of the predicted peptides according to the results of LC-MS/MS, and supplemental figure legends&lt;/p&gt;
Dosimetric analysis of the use of CBCT in diagnostic radiology: sinus and middle ear (2014)

The use of cone beam computed tomography (CBCT) in diagnostic radiology departments is increasing. Several discussions arise whether with the CBCT application, some multi-slice CT (MSCT) examinations can be replaced by it. High hopes are set regarding the dosimetric aspects of CBCT: are patient doses in between those of conventional X-rays and MSCT? In this study, effective dose and organ doses were evaluated for two non-dental CBCT examinations: sinus and middle ear. A comparison with the dose obtained with a MSCT protocol was performed. Moreover, the sinus examination was also compared with the dose obtained by projection radiography (RX). Effective doses were estimated from thermoluminescent detector dose measurements in an anthropomorphic phantom and were compared against Monte Carlo simulations. Results show that the effective dose for the sinus examination is more than three times higher with MSCT than with CBCT and about five times lower with RX compared with CBCT, whereas for the middle ear examination, the effective dose obtained with MSCT is almost six times higher than that of CBCT. Finally, a sensitivity study on the size and position of the CBCT field of view showed the influence of these two factors on the dose received by the patient.
Profiling of circulating microRNAs in children with recent onset of type 1 diabetes (2017)

Type 1 diabetes (T1D) is an autoimmune disease that is clinically silent until the majority of β cells are destroyed. There is an unmet need for reliable and cost-effective biomarkers to predict and diagnose diabetes at an early stage. A number of stable microRNAs (miRNAs) have been reported in serum and plasma and are now being investigated as biomarkers of different diseases. We measured the levels of 745 miRNAs in sera of children with recent-onset T1D and age-matched controls using locked nucleic acid-enhanced (LNA-enhanced) quantitative PCR profiling. Thirty-five miRNAs were significantly different between the groups, and 27 miRNAs were elevated in T1D. Good discriminating power was obtained for 6 miRNAs (miR-454-3p, miR-222-3p, miR-144-5p, miR-345-5p, miR-24-3p, and miR-140-5p), which were not elevated at later stages of diabetes. In silico pathway analysis, based on inferred miRNA target genes, associated glycosaminoglycan biosynthesis as well as PI3K/Akt, MAPK, and Wnt signaling pathways with early stages of T1D. Among the 27 upregulated miRNAs in T1D, 2 miRNAs significantly correlated with hemoglobin A1c (HbA1c), as did 5 of 8 downregulated miRNAs. A total of 134 miRNAs significantly correlated with HbA1c when stratifying hyperglycemia-induced miRNAs from T1D-specific miRNAs. In conclusion, we have identified a serum miRNA pattern of recent-onset T1D and signaling pathways that may be involved in its pathogenesis.
Evaluation of Engineering Surfaces by Diffraction Pattern Analysis (1984)

This paper highlights a new, noncontact technique to assess the differences in surface characteristics of components machined by shaping, milling, turning, grinding processes. The method suggested here is a laboratory analysis based on the process of intensity Fourier Transformation taking place on the surface under test. The results are analyzed by using an in-process microprocessor system to evaluate the surface characteristics immediately.
Stability analysis of large DC solid-state power systems for space (2000)

The purpose of this paper is to present an assessment of the stability analysis of large DC solid-state power systems which are used in spacecraft, such as the International Space Station (ISS) and other satellites. This paper will address the fundamental problems faced in the stability studies of these systems, both prior to, and after, their implementation. Furthermore, a brief description of the type of system, definitions of large-signal and small-signal stability which are applicable to these types of systems, methods of system modeling and simulation, concept of negative impedance instability, and recommendations on methods of stability analysis for these systems will be given.
Artificial Egg Stalks Made of a Recombinantly Produced Lacewing Silk Protein (2012)

Rigid threads: Lacewings protect their eggs from predators by laying them on small stalks (see picture). The stalks have good mechanical properties and, unlike most other silks, a cross β structure. An artificial egg stalk was produced using a designed recombinant variant of a sequenced lacewing egg stalk protein, and it attained 90 % of the tensile strength of a natural egg stalk.
Continuous Transdermal Dopaminergic Stimulation in Advanced Parkinson's Disease (2001)

The objective of the study was to determine the safety and efficacy of increasing doses of Rotigotine CDS in patients with advanced Parkinson's disease. The development of motor complications in Parkinson's disease has been linked to intermittent stimulation of dopamine receptors. Continuous, noninvasive, dopaminergic stimulation has not been available to date. Rotigotine CDS is a lipid-soluble D2 dopamine agonist in a transdermal delivery system that could fill this void. This inpatient study consisted of a 2-week dose escalation phase followed by a 2-week dose maintenance phase at the highest dose (80 cm2). Each individual's L-Dopa dose was back-titrated as feasible. The primary outcome measure was L-Dopa dose, and secondary outcome measures included early morning "off"-L-Dopa Unified Parkinson's Disease Rating Scale motor scores by a blinded evaluator and motor fluctuation data obtained from patient diaries ("on" without dyskinesia, "on" with dyskinesia, and "off"). Seven of 10 subjects provided data that could be evaluated. There were two administrative dropouts, and one individual was eliminated from the study because of recrudescence of hallucinations. The median daily L-Dopa dose decreased from 1,400 to 400 mg (p = 0.018, Wilcoxon test). Unified Parkinson's Disease Rating Scale motor scores were unchanged. Although diary variables improved in most individuals, only the reduction in "off" time attained statistical significance. Adverse effects were mild and consisted mainly of dopaminergic side effects and local skin reactions. The data suggest that Rotigotine CDS is an effective treatment for advanced Parkinson's disease and permits patients to substantially lower L-Dopa doses without loss of antiparkinsonian efficacy. Full-scale controlled clinical trials are warranted. In addition to potential therapeutic benefits, this drug can be used to test the hypothesis that continuous dopaminergic stimulation from the initiation of Parkinson's disease therapy will limit the development of motor complications.
Editorial: Smelly Fumes: Volatile-Mediated Communication between Bacteria and Other Organisms (2016)

Volatiles are small (<300 Da), smelly molecules emitted by all organisms. They have very diverse roles for the producing organism (e.g., as infochemicals or antimicrobial compounds) and fulfill important ecosystem functions. While the importance of plant volatiles has been recognized for more than 30 years, research on microbial volatiles attracted attention only in the last decades. This special issue focuses on several new findings and recent developments in the field of microbial (fungal and bacterial) volatiles, their biological functions and chemical identification, which are highlighted in this editorial.
The Energy Band Gap of AlxGa1-xN (2002)

Combining experimental measurements with an analysis of sample strain, we have determined the "unstrained" energy band gap, Eg, of AlxGa1-xN for 0 ≤x ≤1. Care was taken to grow films with narrow (00.2) and (10.2) X-ray diffraction rocking curve widths, to insure low residual strain in the samples. This is significant because, even for our high quality AlxGa1-xN thin films, residual strain shifts the fitted band gap bowing parameter significantly. For AlxGa1-xN random alloys on GaN films deposited on sapphire, the strain-corrected band gap dependence on alloy composition is fit well by a bowing parameter of b = 0.70 ±0.05. In contrast, AlxGa1-xN films deposited directly on sapphire had much higher X-ray line-widths and their Eg's are not fit well by one value of the bowing parameter. This suggests that material quality may be a significant reason for the large range of bowing parameters reported in the literature.
A Coupled Airflow and Energy Simulation Program for Indoor Thermal Environmental Studies (2000)

Design of a thermally comfortable indoor environment requires detailed information about distribution of air velocity, air temperature, relative humidity, and mean radiant temperature and about the heating/cooling load in a space. This research has developed a coupled airflow and energy simulation program to calculate simultaneously the distributions of indoor airflow and thermal comfort and heating/cooling load. The coupled program can take the nonuniform distributions of indoor airflow and heating/cooling load into account. The program can also provide thermal and fluid boundary conditions normally needed for room airflow calculation. This paper demonstrates the program’s capacity by applying the program to study the thermal environment in a house and an atrium. The coupled flow-and-energy program is recommended for the design of radiative, convective, and hybrid heating and cooling systems.
Joint analysis of vocal tract length and temporal information for robust speech recognition (2013)

This paper presents a joint analysis approach to address the acoustic feature normalization for robust speech recognition. The variations in acoustic environments and speakers are the major challenge for speech recognition. The conventional normalizations of these two variations are separately processed, applying the speaker normalization with an assumption of a noise free condition and applying the noise compensation with an assumption of speaker independency, and thus resulting in a suboptimal performance. The proposed joint analysis approach simultaneously considers the vocal tract length normalization and averaged temporal information of cepstral features. In a data-driven manner, the Gaussian mixture model is used to estimate the conditional parameters in the joint analysis. Experimental results show that the proposed approach achieves a substantial improvement.
Hardness, Toughness, and Brittleness: An Indentation Analysis (1979)

The ratio H/K c , wjere His hardness (resistance to deformation) and K c . is toughness (resistance to fracture), is proposed as an index of brittleness. Indentation mechanics provides the scientific basis for this proposal. The analysis, developed in terms of a model contact system, indicates that all materials are more susceptible to deformation in small‐scale loading events and to fracture in large‐scale events. By normalizing the characteristic dimensions of the two competing processes and the contact load in terms of appropriate functions of H and K c a universal deformation/fracture diagram can be constructed. From this diagram the mechanical response of any material of known hardness and toughness may be predicted for any prospective in‐service contact loading conditions. The concept offers a simple approach to materials classification for design purposes.
Biosynthesis of a novel C30 carotenoid in Bacillus firmus isolates (2012)

It could be shown that the C30 4,4'-diapolycopene-dioate derivatives protect pigmented B. firmus from peroxidative reactions. Under oxidative conditions, this can be an ecological advantage over nonpigmented (=noncarotenogenic) strains that are equally abundant.
Intelligent, automated red team emulation (2016)

Red teams play a critical part in assessing the security of a network by actively probing it for weakness and vulnerabilities. Unlike penetration testing - which is typically focused on exploiting vulnerabilities - red teams assess the entire state of a network by emulating real adversaries, including their techniques, tactics, procedures, and goals. Unfortunately, deploying red teams is prohibitive: cost, repeatability, and expertise all make it difficult to consistently employ red team tests. We seek to solve this problem by creating a framework for automated red team emulation, focused on what the red team does post-compromise - i.e., after the perimeter has been breached. Here, our program acts as an automated and intelligent red team, actively moving through the target network to test for weaknesses and train defenders. At its core, our framework uses an automated planner designed to accurately reason about future plans in the face of the vast amount of uncertainty in red teaming scenarios. Our solution is custom-developed, built on a logical encoding of the cyber environment and adversary profiles, using techniques from classical planning, Markov decision processes, and Monte Carlo simulations. In this paper, we report on the development of our framework, focusing on our planning system. We have successfully validated our planner against other techniques via a custom simulation. Our tool itself has successfully been deployed to identify vulnerabilities and is currently used to train defending blue teams.
Potent Induction of Envelope-Specific Antibody Responses by Virus-Like Particle Immunogens Based on HIV-1 Envelopes from Patients with Early Broadly Neutralizing Responses (2021)

It is generally accepted that an effective HIV-1 vaccine should be able to induce broad-spectrum neutralizing antibodies. Since most of these antibodies require long periods of somatic maturation in vivo , several groups are developing immunogens, based on the HIV envelope protein, that require complex and lengthy immunization protocols that would be difficult to implement in the general population.
Detecting and eliminating memory leaks using cyclic memory allocation (2007)

We present and evaluate a new technique for detecting and eliminating memory leaks in programs with dynamic memory allocation. This technique observes the execution of the program on a sequence oftraining inputs to find m-bounded allocation sites, which have the property that at any time during the execution of the program, the program accesses at most only the last m objects allocated at that site. If the difference between the number of allocated and deallocated objects from the site grows above m throughout the computation, there is a memory leak at that site. To eliminate the leak, the technique transforms the program to use cyclic memory allocation at that site: it preallocates a buffer containing m objects of the type allocated at that site, with each allocation returning the next object in the buffer. At the end of the buffer the allocations wrap back around to the first object. Cyclic allocationeliminates any memory leak at the allocation site -- the total amountof memory required to hold all of the objects ever allocated at the site is simply m times the object size. We evaluate our technique by applying it to several widely-used open source programs. Our results show that it is able to successfully detect and eliminate important memory leaks in these programs. Apotential concern is that the estimated bounds m may be too small, causing the program to overlay live objects in memory. Our results indicate that our bounds estimation technique is quite accurate in practice, providing incorrect results for only one of the 160 m-bounded sites that it identifies. To evaluate the potential impact of overlaying live objects, we artificially reduce the bounds at m-bounded sites and observe the resulting behavior. The resulting overlaying of live objects often does not affect the functionality ofthe program at all; even when it does impair part of the functionality, the program does not fail and is still able to acceptably deliver the remaining functionality.
Preface to Special Section on New Physical Design Techniques for the Next Generation of Integration Technology (2016)

No abstract available.
Silicon retina with correlation-based, velocity-tuned pixels (1993)

A functional two-dimensional silicon retina that computes a complete set of local direction-selective outputs is reported. The chip motion computation uses unidirectional delay lines as tuned filters for moving edges. Photoreceptors detect local changes in image intensity, and the outputs from these photoreceptors are coupled into the delay line, where they propagate with a particular speed in one direction. If the velocity of the moving edges matches that of the delay line, then the signal on the delay line is reinforced. The output of each pixel is the power in the delay line signal, computed within each pixel. This power computation provides the essential nonlinearity for velocity selectivity. The delay line architecture differs from the usual pairwise correlation models in that motion information is aggregated over an extended spatiotemporal range. As a result, the detectors are sensitive to motion over a wide range of spatial frequencies. The design of functional one- and two-dimensional silicon retinas with direction-selective, velocity-tuned pixels is described. It is shown that pixels with three hexagonal directions of motion selectivity are approximately (225 mum)(2) in area in a 2-mum CMOS technology and consume less than 5 muW of power.
A subnanomolar fluorescent probe for protein kinase CK2 interaction studies (2012)

Up-regulation of an acidophilic protein kinase, CK2, has been established in several types of cancer. This cognition has made CK2 an important target for drug development for cancer chemotherapy. The characterization of potential drug candidates, determination of the structure and clarification of the functions of CK2 could be facilitated by the application of small-molecule fluorescent probes that bind to the active site of the enzyme with high affinity and selectivity. We have used a bisubstrate approach for the development of a highly potent inhibitor of CK2. 4,5,6,7-Tetrabromo-1H-benzimidazole was conjugated with peptides containing multiple aspartate residues via different linkers. The design of the inhibitors was by crystallographic analysis of the complex of an inhibitor with the catalytic subunit of the enzyme (CK2α). The inhibitory potency of the synthesized compounds was established in a kinetic assay that used thin layer chromatography for the measurement of the rate of phosphorylation of fluorescently labelled peptide 5-TAMRA-RADDSDDDDD. The most potent inhibitor, ARC-1502 (K(i) = 0.5 nM), revealed high selectivity for CK2α in a panel of 140 protein kinases. Labelling of ARC-1502 with PromoFluor-647 gave the fluorescent probe ARC-1504 that possessed subnanomolar affinity towards both CK2α and the holoenzyme. The probe was used in a fluorescence anisotropy-based binding assay to measure the concentration of CK2α and characterize non-labelled ligands binding to the active site of CK2α.