gebhart/patrepeval huggingface dataset:
Olfactory function and nasal nitric oxide (2007)

Olfactory function and nNO concentration correlate in chronic rhinosinusitis patients but not in healthy subjects. This suggests that both parameters do rather not directly influence each other but it might be the inflammatory processes found in chronic rhinosinusitis that affects olfaction and nNO. Nasal nitric oxide produced by the paranasal sinuses seems not to directly influence olfactory function.
Recursive parameter identification of constrained systems: an application to electrically stimulated muscle (1991)

In the application of real-time identification methods for diagnosis or adaptive control of biomedical systems, there is often known model information that is ignored. Constraints on the allowable values of parameters, which may be based on physical considerations, are often neglected because the information does "fit" easily into commonly used parameter-identification algorithms. In this paper a method of incorporating constraints on model parameters is developed. This method is applicable to most recursive parameter-identification algorithms. It enforces linear equality constraints on identified parameters. The use of this method for the real-time identification of autoregressive moving-average-type time series models, subject to parameter constraints, is described in detail. These constraints may be time varying. At each time step, the parameter estimate obtained by a recursive least squares estimator is orthogonally projected onto the constraint surface. This simple idea, when appropriately executed, enhances the output prediction accuracy of estimated parameters. Using constraint information in this way is important when we do not wish to destroy a "natural" parameterization of the model (by an initial projection to incorporate equality constraints), or when we cannot use a single initial model simplification (because the constraints are time varying or involve inputs and outputs). Because it improves output prediction at future times, this method is advantageous for use in predictive adaptive controllers. The use of this algorithm is demonstrated in the identification of electrically stimulated quadriceps muscles in paraplegic human subjects, using percutaneous intramuscular electrodes. The nonlinear steady-state force versus pulsewidth recruitment characteristic of the electrode-muscle system is identified simultaneously with the input-output muscle response dynamics, using a Hammerstein-type model. Knowledge of the recruitment curve's shape is translated into constraints on the identified parameters. This information improves the experimental predictive quality of the identified model.
Informal firms in Myanmar (2016)

Using survey data on informal firms in Myanmar, a number of issues related to firm-size,productivity, business environment, gender disparity and registration costs and benefits arediscussed. The findings suggest that informal firms in Myanmar are less productive thanformal sector firms but compare favorably with informal firms elsewhere. The education level of themanager is positively correlated with firm productivity but firm-size is not. Access to finance is the most commonly chosen top obstacle, especially by the relatively smaller firms. Few firms find any benefits from registration and particularly so in the relatively smaller cities outside Yangon.
Antibody fucosylation predicts disease severity in secondary dengue infection (2021)

Although antiviral antibodies generally confer protective functions, antibodies against dengue virus (DENV) are associated with enhanced disease susceptibility. Antibodies can mediate DENV infection of leukocytes via Fcγ receptors, likely contributing to dengue disease pathogenesis. To determine if this mechanism accounts for variable disease severity, we examined Fab and Fc structures of anti-DENV antibodies from patients before and after infection and with variable disease outcomes. Neither antibody titers nor neutralizing activity correlated with disease severity in DENV-infected populations. Rather, DENV infection induced a specific increase in immunoglobulin G1 (IgG1) afucosylation, and the levels of afucosylated IgG1 were predictive of dengue disease severity. Thus, the IgG1 fucosylation status represents a robust prognostic tool for dengue disease, highlighting the key role of the Fc glycan structure in dengue pathogenesis.
Optimum Training for MIMO BPSK Transmission (2018)

In this paper, we derive an analytical expression for the bit error rate (BER) of binary phase shift keying (BPSK) symbols transmitted over a multiple-input multiple-output (MIMO) system under channel estimation errors. In this wireless communications system, the receiver uses the linear minimum mean squared error (LMMSE) estimator to estimate the channel matrix. The error in this estimation affects the following estimation that is used to recover the transmitted symbols. It is shown that the channel estimation error is Gaussian and hence the convex Gaussian min-max theorem (CGMT) can be applied to analyze the error of the signal estimation stage and finally obtain an expression for the BER. We use the BER expression to obtain the optimal pilot power allocation under a total transmit energy constraint. Numerical results show close matching between theory and simulations.
P1–418: Early effects of naturally secreted Aβ on hippocampal synapses (2006)

In Alzheimer's disease amyloid β (Aβ) protein exists in various molecular forms, and eventually aggregates into insoluble plaques. Increasing evidence suggests that soluble oligomers of Aβ are responsible for distinct synaptic and cognitive deficits even before mature pathology has accumulated. Previously, it was shown that sub–nanomolar concentrations of Aβ, present in medium conditioned by CHO cells expressing APP V717F mutation (7PA2), can acutely inhibit hippocampal long–term potentiation (LTP) (Klyubin et al. 2005). When injected into the lateral ventricle of rats in vivo, these cell–derived soluble oligomers alter memory of a complex learned behavior (Cleary et al., 2005). Here we investigated the early effects of applying low concentrations of oligomeric Aβ on dendritic spine morphology and synaptic connections of hippocampal neurons. Cultured hippocampal neurons incubated for 1 hour with the CHO 7PA2 cells conditioned medium, containing defined concentrations of Aβ (4 to 80 pM), showed extensive changes in spine morphology and synaptic composition. Using high resolution imaging we found that in this short time interval dendritic spine number was reduced and remaining protrusions were significantly longer and thinner than those seen under control conditions. These changes were also monitored live in individual neurons using time–lapse microscopy. In addition to these morphological changes, synaptophysin clusters but not VGAT clusters were decreased in number and size suggesting that a change in the excitatory to inhibitory synapse ratio may accompany the morphological alterations of the postsynaptic dendritic spines. The rapidity of these synaptic morphological changes provides a structural correlate to the previously described rapid LTP inhibition (Klyubin et al., 2005). In addition, this approach allows us for the first time to monitor in living neurons the fate of single dendritic spines and synapses exposed to an extracellular increase of soluble cell–derived Aβ.
Profibrotic interleukin-33 is correlated with uterine leiomyoma tumour burden (2013)

No funding, no conflict of interest.
Early Hospital Discharge After Helicopter Transport of Pediatric Trauma Patients (2018)

Triage of pediatric trauma patients to HAA remains difficult. There remains potential for improvement, particularly as regards interhospital HAA overtriage, but well developed transfer protocols (such in-state protocols) may help.
Research on improving photovoltaic fault voltage support capability using virtual impedance (2021)

The network connection of photovoltaic power generation system is connected to the power grid through public connection points. If the grid side is short circuited, the system connected to the grid can cause serious accidents, such as shutting down the equipment due to sudden voltage changes. This document introduces virtual obstacles to modify the reference signal of voltage control link and play a role of voltage support during fault. The simulation and test of MATLAB / Simulink shall verify that the proposed control strategy allows the integrated photovoltaic grid system to successfully pass the network error.
Spring Forward, Fall Back [President's Message] (2023)

Welcome to a new year in CIS! You are reading this in the first issue of CIM for 2023, but I'm writing this message right as the US switches from Daylight Savings Time to Standard Time. The title of this article is how I was taught to remember which direction to turn the clocks in this biannual ritual. But it now reminds me to reflect a little on 2022 and then to spring forward in anticipation of the new year.
Catalytically Active Peptide–Gold Nanoparticle Conjugates: Prospecting for Artificial Enzymes (2020)

Abstract The self‐assembly of peptides onto the surface of gold nanoparticles has emerged as a promising strategy towards the creation of artificial enzymes. The resulting high local peptide density surrounding the nanoparticle leads to cooperative and synergistic effects, which result in rate accelerations and distinct catalytic properties compared to the unconjugated peptide. This Minireview summarizes contributions to and progress made in the field of catalytically active peptide–gold nanoparticle conjugates. The origin of distinct properties, as well as potential applications, are also discussed.
Analisi delle prestazioni di un gruppo integrato cogeneratore con motore a gas e pannelli fotovoltaici (2012)

Oggetto dello studio è l'analisi sperimentale e la modellazione di un gruppo elettrogeno a gas naturale in assetto cogenerativo, con possibilità di inseguimento del carico termico od elettrico, abbinato ad un impianto fotovoltaico e ad un sistema di accumulo elettrochimico. Esso rientra in un più ampio progetto riguardante la generazione distribuita, denominato Enerplan, condotto da AREA Science Park in collaborazione con il Dipartimento di Ingegneria Civile e Architettura dell'Università degli Studi di Trieste. L’indagine sperimentale ha riguardato il rilievo di numerosi dati funzionali ed il calcolo dei rendimenti elettrici e termici in diversi assetti operativi. Inoltre è stato realizzato un modello di simulazione utile per valutare le prestazioni tecnico-economiche del sistema integrato e per condurre analisi sul comportamento dinamico del sistema in presenza di diverse strategie di controllo.
Sequential Expression, Activity and Nuclear Localization of Prolyl Oligopeptidase Protein in the Developing Rat Brain (2010)

Prolyl oligopeptidase (POP) is a serine protease that hydrolyzes peptides shorter than 30-mer. Some evidence has recently been obtained that POP can generate protein-protein interactions and therefore participate in various physiological and pathological events. Several studies have reported that POP may be involved in neurogenesis since its activity increases during development and can be found in the nucleus of proliferating tissues. In cell cultures, POP has been shown to be localized in the nucleus, but only early in the development, since during maturation it is moved to the cytosol. We have now studied for the first time the expression of POP protein, its enzymatic activity and nuclear localization in vivo in the developing rat brain. We observed that enzymatic activity of POP is highest on embryonic day 18 while the protein amounts reach their peak at birth. Furthermore, POP is located in the nucleus only early in the development but is transferred to the cytosol already before parturition. Our in vivo results confirm the previous cell culture results supporting the role of POP in neurogenesis. A discordance of antenatal protein amounts and enzymatic activities is suggesting a tight regulation of POP activity and possibly even a nonhydrolytic role at that stage.
ChemInform Abstract: Synthesis of Novel Solid‐State Compounds in Supercritical Solvents: Preparation and Structure of K2Ag12Se7 in Supercritical Ethylenediamine. (1993)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Multicomponent oxide composites for carriers in catalytic applications (2021)

Abstract Binary, ternary, and quaternary composite oxides of rare earths (La and Ce) with one or more of aluminum, magnesium, and zirconium, prepared by coprecipitation are studied. Potential use is carrier in steam or dry reforming of hydrocarbons and ethanol. Individual components influence specific surface area, porosity, acidity, hydrothermal stability, and oxygen storage capacity (OSC) differently. Interaction effects between components further influence these properties resulting in unexpected trends. Alumina and magnesia form solid solutions with zirconia until 650℃. Magnesia imparts better hydrothermal stability to zirconia. Aluminum and magnesium form MgAl 2 O 4 spinel in ternary composites. Specific surface area varies linearly with alumina content. Alumina influences porosity, whereas magnesia influences pore diameter. The composites are mesoporous. Only binary composites present unimodal, pore size distribution. Composites containing alumina present type H2 isotherms while the remaining composites present H3 type isotherms. OSC increases over ZrO 2 /CeO 2 5.7 to 15.3 molar. Magnesia and alumina affect microstructure and hydrothermal stability in contrasting ways. Thermogravimetry indicates that ternary composites of zirconia with alumina or magnesia form through oxolation. Surface hydroxyls with varying acidity are seen by FTIR in as synthesized samples. Magnesia and zirconia influence acidity in opposite ways, which impacts deactivation in the decomposition of 2‐methyl‐3‐butyn‐2‐ol.
Features Distinguishing Epstein-Barr Virus Infections of Epithelial Cells and B Cells: Viral Genome Expression, Genome Maintenance, and Genome Amplification (2009)

Epstein-Barr virus (EBV) is associated with malignant diseases of lymphoid and epithelial cell origin. The tropism of EBV is due to B-cell-restricted expression of CD21, the major receptor molecule for the virus. However, efficient infection of CD21- epithelial cells can be achieved via transfer from EBV-coated B cells. We compare and contrast here the early events following in vitro infection of primary B cells and epithelial cells. Using sensitive, quantitative reverse transcription-PCR assays for several latent and lytic transcripts and two-color immunofluorescence staining to analyze expression at the single cell level, we confirmed and extended previous reports indicating that the two cell types support different patterns of transcription. Furthermore, whereas infection of B cells with one or two copies of EBV resulted in rapid amplification of the viral genome to >20 copies per cell, such amplification was not normally observed after infection of primary epithelial cells or undifferentiated epithelial lines. In epithelial cells, EBNA1 expression was detected in only ca. 40% of EBER+ cells, and the EBV genome was subsequently lost during prolonged culture. One exception was that infection of AGS, a gastric carcinoma line, resulted in maintenance of EBNA1 expression and amplification of the EBV episome. In contrast to B cells, where amplification of the EBV episome occurred even with a replication-defective BZLF1-knockout virus, amplification in AGS cells was dependent upon early lytic cycle gene expression. These data highlight the influence of the host cell on the outcome of EBV infection with regard to genome expression, amplification, and maintenance.
Microwave magnetoelectric coupling and ferromagnetic resonance frequency tuning of a Co₂MnSb/GaAs/PZN-PT heterostructure (2011)

A systematic study of electric-field-tuned ferromagnetic resonance (FMR) of a ferroelectric/ferromagnetic/semiconductor multiferroic heterostructure, consisting of a Co2MnSb epitaxial film grown on a GaAs substrate bonded to a lead zinc niobate-lead titanate crystal, is reported. The films, grown by pulsed laser deposition, were studied for their crystallographic structure, magnetocrystalline anisotropy, and magnetostrictive and ferromagnetic resonance properties. Ferromagnetic resonance measurements were carried out at X-band frequency under the application of electric fields with external magnetic fields applied along the [110], [100], [11̄0], and [001] directions of the Heusler film. Magnetic anisotropy fields were derived from the angular dependence of FMR measurements, yielding an in-plane fourth-order anisotropy constant K1=-150×103 erg/cm3 and a perpendicular second-order anisotropy constant K=12×103 erg/cm3. A theoretical model, which includes the effects of electric-field tuning, is presented to calculate the tunability of the ferromagnetic resonance frequency of the multiferroic heterostructure. The multiferroic heterostructure exhibits a frequency tuning of 450 MHz under the application of an electric field of 10 kV cm-1, corresponding to a magnetoelectric coupling coefficient of 8.8 Oe cm kV-1. This work explores the potential of electronically controlled multiferroic devices for use in microwave integrated circuits, while concomitantly establishing the basic theoretical foundation allowing for the calculation of microwave tunability for this and other heterostructures. © 2011 American Physical Society.
Biosynthetic Microcin J25 Exerts Strong Antibacterial, Anti-Inflammatory Activities, Low Cytotoxicity Without Increasing Drug-Resistance to Bacteria Target (2022)

Multidrug resistant (MDR) bacterial infection has emerged, raising concerns about untreatable infections, and posing the highest health risks. Antimicrobial peptides (AMPs) are thought to be the best remedy for this problem. Here, we showed biosynthetic microcin J25 (MccJ25) exhibited excellent bactericidal activity against standard and clinically relevant veterinary MDR strains with high stability, no cytotoxicity, and no increase in drug resistance. Analysis of antimicrobial mechanism possessed by sensitive enterotoxigenic <i>Escherichia coli</i> (ETEC) based on electron microscopy and Sytox Green methods was carried out. Results showed excellent activity against ETEC was due to permeabilizing bacterial membranes and strong affinity. MccJ25 exhibited high endotoxin-neutralizing activity in both <i>in vivo</i> and <i>in vitro</i> environments, and mice exposed to lipopolysaccharide (LPS) showed decreased plasma LPS levels and improved survival after administration of MccJ25. In an LPS-treated mouse septicemia model, MccJ25 treatment significantly alleviated inflammatory responses by inhibiting proinflammatory factor secretion and expression. In a mouse <i>E. coli</i> infection model, administration of MccJ25 effectively improved host defense against clinically source cocktail of multidrug-resistant <i>E. coli</i> strains induced intestinal inflammation and bacteria dissemination. Results of studies on anti-inflammatory mechanisms showed that MccJ25 downregulated nuclear factor kappa B kinase and mitogen-activated protein kinase, thereby reducing the production of toll-like receptor 4, myeloid differentiation factor 88 and decreasing the key proinflammatory cytokines. These findings clarify MccJ25 may be an ideal antibacterial/antiendotoxic drug candidate that has the potential to further guide the development of anti-inflammatory and/or antimicrobial agents in the war against MDR bacterial infection.
Supplemental Table 4 from Nitrated Polycyclic Aromatic Hydrocarbon (Nitro-PAH) Signatures and Somatic Mutations in Diesel Exhaust-Exposed Bladder Tumors (2023)

&lt;p&gt;specific TP53 mutations and ever diesel&lt;/p&gt;
Improving layer 3 handoff delay in IEEE 802.11 wireless networks (2006)

In this paper we will analyze the many components of a L3 hand-off and will introduce a novel algorithm for reducing the L3 hand-off time. We will introduce the concept of Temporary IP address (TEMP_IP) as a way to resume communication immediately after the handoff while waiting for the DHCP server to assign us a new IP address (NEW_IP). We will show how, with our approach, it is possible to reduce the L3 handoff latency to values that in some cases allow us to have seamless VoIP sessions.
Two stage classifierfor Arabic Handwritten Character Recognition (2015)

In this paper we will present a two phase method for isolated Arabic handwritten character recognition system. The new method combines two levels based on two classifiers, a public and a private according to the similar features among characters. In the first level, we built a public classifier to deal with all character groups, each group contains characters with overlapped feature. The public classifier classifies the characters in the SUST-ARG dataset (Sudan University for Sciences and Technology Arabic Recognition Group) to specified groups. In the second level, we created a private classifier for each group to recognize and classify the characters within a group. The system was applied to 34 Arabic characters and achieved 78.79% recognition rate for the tested dataset within the first level of the grouping model and achieved 93% recognition rate for the tested dataset using the two level models.
Respiratory rate variability in sleeping adults without obstructive sleep apnea (2016)

Characterizing respiratory rate variability (RRV) in humans during sleep is challenging, since it requires the analysis of respiratory signals over a period of several hours. These signals are easily distorted by movement and volitional inputs. We applied the method of spectral analysis to the nasal pressure transducer signal in 38 adults with no obstructive sleep apnea, defined by an apnea-hypopnea index <5, who underwent all-night polysomnography (PSG). Our aim was to detect and quantitate RRV during the various sleep stages, including wakefulness. The nasal pressure transducer signal was acquired at 100 Hz and consecutive frequency spectra were generated for the length of the PSG with the Fast Fourier Transform. For each spectrum, we computed the amplitude ratio of the first harmonic peak to the zero frequency peak (H1/DC), and defined as RRV as (100 - H1/DC) %. RRV was greater during wakefulness compared to any sleep stage, including rapid-eye-movement. Furthermore, RRV correlated with the depth of sleep, being lowest during N3. Patients spent most their sleep time supine, but we found no correlation between RRV and body position. There was a correlation between respiratory rate and sleep stage, being greater in wakefulness than in any sleep stage. We conclude that RRV varies according to sleep stage. Moreover, spectral analysis of nasal pressure signal appears to provide a valid measure of RRV during sleep. It remains to be seen if the method can differentiate normal from pathological sleep patterns.
Research on essential safety performance for interleaving magnetics buck converter (2011)

In order that the maximum released energy of the output short circuit is less to meet the essential safety requirements in the buck converter,the paper proposes that magnetic integration technique is applied to the interleaving buck converter.By properly designing the channel number N and duty cycle D,the circuit can achieve rather ideal output current ripple.Taking two-interleaving magnetics buck converter for example,the reverse coupling integration between inductance and inductance can reduce the single channel output current ripple,which may reduce the maximum released energy of the output short circuit and improve the transient response speed of the circuit.These are beneficial to the realization of essential safety.The interleaving magnetics buck converter is simulated in MATLAB and experimented.Finally,the result proves the correctness of the proposed method.