gebhart/patrepeval huggingface dataset:
Abstract LB-323: Self-reported sleep duration and subsequent risk of colorectal cancer in two large cohorts of women and men (2012)

Abstract Background: Short sleep duration was associated with an increased risk of colorectal adenomas in a recent report. To date, no data are available on the relationship between sleep duration and colorectal cancer risk. Method: We prospectively followed 76,368 women aged 40 to 73 years in the Nurses’ Health Study and 28,676 men aged 41 to 79 years in the Health Professionals Follow-up Study who reported their habitual sleep duration in the mid-1980s. We used Cox proportional hazards regression models to estimate multivariable relative risks (MV RRs) and 95% confidence intervals (CIs) adjusting for known risk factors (dietary and non-dietary) for colorectal cancer. Results: A total of 1,925 incident colorectal cancer cases (1,264 in women and 661 in men) were documented during up to 22 years of follow-up. The median of sleep duration was 7 hours in both cohorts and was used as the reference group. In both age-adjusted and the multivariate models, long sleep duration (i.e., at least 9 hours of sleep) was significantly positively associated with risk of colorectal cancer in men (MV RR=1.49; 95%CI: 1.10, 2.03) but not in women (MV RR=1.10; 95%CI: 0.85, 1.43). However, for the same comparison (i.e., at least 9 hours vs. 7 hours of sleep), among overweight (body mass index at least 25 kg/m2) individuals, we found significant positive associations for both men (MV RR=2.66; 95%CI: 1.81, 3.90) and women (MV RR=1.42; 95%CI: 1.01, 1.99). Short sleep duration (i.e., 5 hours or less of sleep) was not associated with colorectal cancer risk in either men (MV RR=0.65; 95%CI: 0.33, 1.28) or women (MV RR=1.14; 95%CI: 0.88, 1.48). Results were essentially unchanged when we excluded cases occurred in the first 4 years of follow-up. In addition, the association was not significantly modified by physical activity, alcohol consumption, endoscopy screening, family history of colorectal cancer, menopausal status, or shift work (women only). Conclusion: These prospective data from two large cohorts suggest that overweight men and women with a sleep duration of 9 or longer hours had a significantly increased risk of developing colorectal cancer when compared to those with 7 hours of sleep, which cannot be explained by known risk factors or reverse causality. The potential mechanisms behind this association deserve further investigation. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 103rd Annual Meeting of the American Association for Cancer Research; 2012 Mar 31-Apr 4; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2012;72(8 Suppl):Abstract nr LB-323. doi:1538-7445.AM2012-LB-323
Band alignment at metal/organic and metal/oxide/organic interfaces (2008)

Charge injection at metal/organic interfaces dictates the performance, lifetime, and stability of organic electronic devices. We demonstrate that interface dipole theory, originally developed to describe Schottky contacts at metal/semiconductor interfaces, can also accurately describe the injection barriers in real organic electronic devices. It is found that theoretically predicted hole injection barriers for various archetype metal/organic and metal/oxide/organic structures are in excellent agreement with values extracted from experimental transport measurements. Injection barriers at metal/organic and metal/oxide/organic interfaces can therefore be accurately predicted based on the knowledge of only a few fundamental material properties of the oxide and organic layers.
Cyclic GMP phosphodiesterase from bovine retina Amino acid sequence of the α‐subunit and nucleotide sequence of the corresponding cDNA (1987)

The alpha-subunit primary structure of cyclic GMP phosphodiesterase has been determined by parallel analysis of the protein amino acid sequence and the corresponding cDNA nucleotide sequence. The enzyme alpha-subunit contains 858 amino acid residues, its N-terminal amino group being acetylated. The partial primary structure of the enzyme beta-subunit has also been elucidated. A significant homology has been found between the alpha- and beta-subunits of cGMP phosphodiesterase.
48.5: Roll‐to‐Roll Manufacturing Process for Full Color Electrophoretic Film (2006)

Abstract We report the process development work on roll‐to‐roll fabrication of EPD film that enables the making of full color EPD display. Through the incorporation of inkjet printing process, Microcup® web can be printed with colored fluids to form designated color pattern at sub pixel level. Existing roll‐to‐roll Microcup® EPD manufacturing process can be modified to accommodate the printing step and the processes can be coordinated in such to prevent the mixing of different colored fluids during web processing.
A highly sensitive and nonradioactive mutation detection method based on vertical gradient temperature single-strand conformation polymorphism (2001)

The single-strand conformation polymorphism (SSCP) method is widely used for mutation detection. The sensitivity of the method depends on several factors, most importantly on the temperature at which electrophoresis of single-stranded DNA (ssDNA) takes place. The temperature has a profound effect on the folded conformation of ssDNA. The temperature factor is predominantly determined empirically in conventional SSCP, which can be very tedious especially when a large number of different DNA samples need to be screened. We have devised a novel SSCP method based on a vertical gradient temperature (VGT), which automatically subjects ssDNA to various temperatures in the same electrophoresis. The theory behind VGT-SSCP protocol is that when ssDNA is subjected to run in a wide range of gradient temperature, it will automatically acquire optimal resolution at an optimal temperature to distinguish between the wild type and the mutant type ssDNA. The sensitivity level of mutation detection of VGT-SSCP depends on whether the corresponding optimal secondary structure of a mutant DNA strand is within the preset gradient temperature range. In summary, the VGT-SSCP is a simple and robust nonradioactive method that is more sensitive than constant-temperature SSCP in detecting unknown mutations.
A Brief History of the Graphic Novel (2018)

The main visual device used in a comic book or graphic novel is a sequential array of images. As a visual communicative device, the sequential array of images has a long history. We see it in prehistoric cave art, the wall art of ancient Egyptian tombs, comic strips in newspapers, and most recently the digitally promulgated graphic novel, among other instances. As a visual narrative it is both impactful and highly recognisable. This is because it reduces the amount of information needed to communicate a succinct message using abstract iconography. This iconography evolved over the millennia until it formed its own lexicon and lingua franca within its media genre. Most recently, its conventions can now be relied on to communicate complex stories using digital media and the internet. This paper reviews the literature on the origins of the comic book art form, its current state and possible future directions. It provides an argument for the efficiency and enjoyment of this art form as a method for communicating information visually.//////document is a "live" template and already defines the components of your paper [title, text, heads, etc.] in its style sheet.
Synthesis of amino-.beta.-lactams by the photolytic reaction of imines with pentacarbonyl[(dibenzylamino)carbene]chromium(0) (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of amino-.beta.-lactams by the photolytic reaction of imines with pentacarbonyl[(dibenzylamino)carbene]chromium(0)Christian Borel, Louis S. Hegedus, Jurg Krebs, and Yoshitaka SatohCite this: J. Am. Chem. Soc. 1987, 109, 4, 1101–1105Publication Date (Print):February 1, 1987Publication History Published online1 May 2002Published inissue 1 February 1987https://pubs.acs.org/doi/10.1021/ja00238a018https://doi.org/10.1021/ja00238a018research-articleACS PublicationsRequest reuse permissionsArticle Views682Altmetric-Citations76LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Effects of systemic administration of methylprednisolone on residual hearing in an animal model of cochlear implantation (2010)

CT scans confirmed that the array was well positioned in tested animals. From days 3 to 21, a hearing loss of about 30 dB on all frequencies was observed in the implanted nontreated group. This hearing loss remained stable during the whole follow-up period. Compared with implanted nontreated animals, the hearing threshold shift decreased by 12 dB in animals treated with methylprednisolone.
Optical extinction and scattering cross sections of plasmonic nanoparticle dimers in aqueous suspension (2016)

Absolute extinction and scattering cross sections for gold nanoparticle dimers were determined experimentally using a chemometric approach involving singular-value decomposition of the extinction and scattering spectra of slowly aggregating gold nanospheres in aqueous suspension. Quantitative spectroscopic data on plasmonic nanoparticle assemblies in liquid suspension are rare, in particular for particles larger than 40 nm, and in this work we demonstrate how such data can be obtained directly from the aggregating suspension. Our method can analyse, non invasively, the evolution of several sub-populations of nanoparticle assemblies. It may be applied to other self-assembling nanoparticle systems with an evolving optical response. The colloidal systems studied here are based on 20, 50 and 80 nm gold nanospheres in aqueous solutions containing sodium lipoate. In these systems, the reversible dimerisation process can be controlled using pH and ionic strength, and this control is rationalised in terms of DLVO theory. The dimers were identified in suspension by their translational and rotational diffusion through scattering correlation spectroscopy. Moreover, their gigadalton molecular weight was measured using electrospray charge-detection mass spectrometry, demonstrating that mass spectrometry can be used to study nanoparticles assemblies of very high molecular mass. The extinction and scattering cross sections calculated in the discrete-dipole approximation (DDA) agree very well with those obtained experimentally using our approach.
Gezielte Herstellung von Porensystemen mit definierten Eigenschaften (1975)

Abstract Bei der Herstellung poröser Festkörper können drei Prinzipien unterschieden werden: Aggregation bzw. Vernetzung, Subtraktion und Rekristallisation. Die Bildung des Porensystems wird dabei zum einen von substanzspezifischen zum anderen von verfahrensspezifischen Faktoren bestimmt. Bei Kenntnis der Wirkung und Wichte dieser Faktoren lassen sich die Parameter der Hohlraumstruktur reproduzierbar und systematisch variieren. Dies wird anhand der Herstellungsverfahren folgender Produkte demonstriert: synthetische Zeolithe, Aktivkohle, poröses Glas, poröses Siliciumdioxid, poröses Thoriumoxid, Membranfilter, Styrol‐Divinylbenzol‐Copolymere. Im Hinblick auf den Einsatz poröser Adsorbentien müssen die Kenngrößen der Hohlraumstruktur auf die Effektivität des jeweiligen Prozesses optimiert werden. In diese Optimierung müssen auch die Form und die Größenverteilung der porösen Teilchen miteinbezogen werden.
The relationship between albuminuria and hypercholesterolemia (2003)

Increasing albuminuria is associated with continuous, and graded increase in the odds of high serum TC and LDL cholesterol levels. Our results call for future follow-up studies to confirm if albuminuria precedes the development of hypercholesterolemia.
Treatment of Facial Hypopigmented Scars by the Laser Hole Technique Using a Nonfractional Carbon Dioxide Laser in Asians (2018)

The laser hole technique using a nonfractional carbon dioxide laser may be an excellent option for simultaneously treating the color and texture of superficial or thin hypopigmented facial scars in Asians.
Human pancreatic amylase is encoded by two different genes (1988)

Journal Article Human pancreatic amylase is encoded by two different genes Get access Peter C. Groot, Peter C. Groot Search for other works by this author on: Oxford Academic PubMed Google Scholar Maria J. Bleeker, Maria J. Bleeker Search for other works by this author on: Oxford Academic PubMed Google Scholar Jan C. Pronk, Jan C. Pronk Search for other works by this author on: Oxford Academic PubMed Google Scholar Fré Arwert, Fré Arwert Search for other works by this author on: Oxford Academic PubMed Google Scholar Willem H. Mager, Willem H. Mager 1Department of Biochemistry, Vrije Universiteit, de Boelelaan 1083, 1081 HV Amsterdam, The Netherlands Search for other works by this author on: Oxford Academic PubMed Google Scholar Rudi J. Planta, Rudi J. Planta 1Department of Biochemistry, Vrije Universiteit, de Boelelaan 1083, 1081 HV Amsterdam, The Netherlands Search for other works by this author on: Oxford Academic PubMed Google Scholar Aldur W. Eriksson, Aldur W. Eriksson Search for other works by this author on: Oxford Academic PubMed Google Scholar Rune R. Frants Rune R. Frants Search for other works by this author on: Oxford Academic PubMed Google Scholar Nucleic Acids Research, Volume 16, Issue 10, 25 May 1988, Page 4724, https://doi.org/10.1093/nar/16.10.4724 Published: 25 May 1988 Article history Accepted: 09 April 1988 Published: 25 May 1988
Binary synthesis (2007)

Recent high-level synthesis approaches and C-based hardware description languages attempt to improve the hardware design process by allowing developers to capture desired hardware functionality in a well-known high-level source language. However, these approaches have yet to achieve wide commercial success due in part to the difficulty of incorporating such approaches into software tool flows. The requirement of using a specific language, compiler, or development environment may cause many software developers to resist such approaches due to the difficulty and possible instability of changing well-established robust tool flows. Thus, in the past several years, synthesis from binaries has been introduced, both in research and in commercial tools, as a means of better integrating with tool flows by supporting all high-level languages and software compilers. Binary synthesis can be more easily integrated into a software development tool-flow by only requiring an additional backend tool, and it even enables completely transparent dynamic translation of executing binaries to configurable hardware circuits. In this article, we survey the key technologies underlying the important emerging field of binary synthesis. We compare binary synthesis to several related areas of research, and we then describe the key technologies required for effective binary synthesis: decompilation techniques necessary for binary synthesis to achieve results competitive with source-level synthesis, hardware/software partitioning methods necessary to find critical binary regions suitable for synthesis, synthesis methods for converting regions to custom circuits, and binary update methods that enable replacement of critical binary regions by circuits.
International technology transfer : issues and policy options (1979)

Technology is a vital part of the development process, a necessary input into all activity. Because of the historical domination of research and development by developed countries, a very large part of the technology used is transferred from developed countries. The transfer raises four major issues: those of the costs of the transfer, the appropriateness of products and techniques which are transferred, the effects of the transfer on learning and technological development in LDCs, and the effects on independence. The paper considers the consequence of the transfer and the range of policies that might be adopted, nationally and internationally, in relation to each of these issues. It is argued that the appropriate policies will vary according to the stage of development of each country, its technological capacity and its own objectives. However, in general it is concluded that an active technology policy is called for if the costs associated with technology transfer are to be reduced and the benefits increased.
Primary structures of six antimicrobial peptides of rabbit peritoneal neutrophils. (1985)

Six microbicidal peptides, NP-1, NP-2, NP-3a, NP-3b, NP-4, and NP-5, from rabbit peritoneal neutrophils were characterized. As a family, the peptides were 32-34 residues in length, were cystine- and arginine-rich, and each contained three intramolecular disulfide bonds. Within their sequences, the six peptides shared 11-residue positions, which included the six half-cystines contained in each peptide. NP-1 and NP-2 differed by a single residue and were identical in their respective sequences to MCP-1 and MCP-2, the peptide analogs from rabbit alveolar macrophages. NP-4 and NP-5 were homologous in 27 of their residues, but NP-3a and NP-3b shared little more than the 11-residue backbone common to all members of this peptide family.
Evaluation of transdermal permeability of pentoxifylline gel: in vitro skin permeation and in vivo microdialysis using Wistar rats. (2007)

The aim of the present work was to evaluate the transdermal permeability of pentoxifylline gel in vitro and in vivo. Gel was prepared with carbomer 934 as the base, and the Wistar rat was chosen as an animal model. The effects of percutaneous enhancers on the transdermal permeability of pentoxifylline gel were investigated by in vitro permeation experiments. Cumulative permeation at different times was determined by HPLC. 3% Azone and 5% propylene glycol were used as collaborative enhancers in an optimal formulation. Topical concentrations at different times were measured by microdialysis in vivo. The transdermal process of pentoxifylline fits to a zero-order kinetic equation, and its release profile remains of the zero-order despite the addition of enhancers. In addition, a good in-vitro-in-vivo correlation was achieved.
A new convexity measure for polygons (2004)

Abstract-Convexity estimators are commonly used in the analysis of shape. In this paper, we define and evaluate a new convexity measure for planar regions bounded by polygons. The new convexity measure can be understood as a "boundary-based" measure and in accordance with this it is more sensitive to measured boundary defects than the so called "area-based" convexity measures. When compared with the convexity measure defined as the ratio between the Euclidean perimeter of the convex hull of the measured shape and the Euclidean perimeter of the measured shape then the new convexity measure also shows some advantages-particularly for shapes with holes. The new convexity measure has the following desirable properties: 1) the estimated convexity is always a number from (0, 1], 2) the estimated convexity is 1 if and only if the measured shape is convex, 3) there are shapes whose estimated convexity is arbitrarily close to 0, 4) the new convexity measure is invariant under similarity transformations, and 5) there is a simple and fast procedure for computing the new convexity measure.
A system architecture for intelligent implantable biotelemetry instruments (2003)

A system architecture for intelligent implantable biotelemetry instruments is presented. The system consists of a modular chip set interconnected by a synchronous serial bus. A user-programmable microprocessor controls all functions, including data acquisition, actuator control and telemetry. Data acquisition is performed by an eight-channel conditioning chip with programmable gain, bandwidth, and sampling rates. An advanced telemetry unit allows bidirectional communication of both data and commands, while providing an error-detection scheme to ensure integrity.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Fluorescence fluctuations analysis in nanoapertures: physical concepts and biological applications (2008)

During the past years, nanophotonics has provided new approaches to study the biological processes below the optical diffraction limit. How single molecules diffuse, bind and assemble can be studied now at the nanometric level, not only in solutions but also in complex and crowded environments such as in live cells. In this context fluorescence fluctuations spectroscopy is a unique tool since it has proven to be easy to use in combination with nanostructures, which are able to confine light in nanometric volumes. We review here recent advances in fluorescence fluctuations' analysis below the optical diffraction limit with a special focus on nanoapertures milled in metallic films. We discuss applications in the field of single-molecule detection, DNA sequencing and membrane organization, and underscore some potential perspectives of this new emerging technology.
A Method for Fast Digital Image Stabilization (2008)

A fast digital image stabilization method based on morphological edge matching is proposed. Firstly, morphological edge detection and matching is used to estimate the local movement vectors calculated by logical correlation operator instead of pixel-wise gray arithmetic operators, the computation cost is greatly reduced. Secondly, in order to remove the undesired displacement due to several undesired conditions, the exclude decision is made to judge whether the local movement vector is desired or not, and finally global movement vector is obtained by weighted median to further enhance there liability. Experiments show that this method is fast and efficient for image stabilization.
First Quasi-Single-Mode Transmission over Transoceanic Distance using Few-mode Fibers (2015)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text F. Yaman, S. Zhang, Y. Huang, E. Ip, J. D. Downie, W. A. Wood, A. Zakharian, S. Mishra, J. Hurley, Y. Zhang, I. B. Djordjevic, M. Huang, E. Mateo, K. Nakamura, T. Inoue, Y. Inada, and T. Ogata, "First Quasi-Single-Mode Transmission over Transoceanic Distance using Few-mode Fibers," in Optical Fiber Communication Conference Post Deadline Papers, OSA Technical Digest (online) (Optica Publishing Group, 2015), paper Th5C.7. Export Citation BibTex Endnote (RIS) HTML Plain Text Get Video Citation alert Save article