gebhart/patrepeval huggingface dataset:
Memory efficacious pattern matching intrusion detection system (2013)

In today's web-enabled world, the communications happening over the network is intensifying at a capacious rate. Not all communications are credible and malpractice can arise anywhere, anytime. If the normal traffic is slightly modified to delude the intrusion detection system, then the traditional systems might not be able to discern the same effectively. Thus, a system that could detect and ferret out the novel attacks has been proposed. Since any number of users can use a web page, maintaining the availability of the resources and allocating them to the active users as per their need is very essential. The multi-thread concept is used to share the resources that each client can use. Attribute Selection Algorithm is used as the feature extraction algorithm in weka, to yield those relevant features pertaining to the user's request and helps in achieving a more accurate result. Memory efficiency is brought in with the cascading binary search tree. The patterns are efficiently stored and hence the search for the presence of an attack is accomplished effectively. An Intrusion Detection System which is memory efficient and effective enough in detecting attacks and reducing the false positives is thus proposed.
ChemInform Abstract: 2‐(Heteroatom‐Substituted)methyl Penems. Part 4. Oxygen Derivatives. (1990)

Abstract Reaction of the penem (I) with the carboxylic acids (II) yields the 2‐(acyloxymethyl) penems (III).
Applications of computational intelligence in optical networks (2011)

Computational intelligence techniques have appeared as efficient alternatives to solve complex problems, such as in multimodal and multidimensional spaces and optimization of multi-objective problems. These approaches are generally bio-inspired and many algorithms have been proposed in recent years. In this last decade, some efforts have been carried in order to demonstrate that these techniques can be useful to tackle tough problems in optical networks. This paper presents a review of some applications of computational intelligence in optical networking, such as in the impairment-aware routing and wavelength assignment, regenerator placement and physical topology design.
Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAP-K2) as an Antiinflammatory Target: Discovery and in Vivo Activity of Selective Pyrazolo[1,5-a]pyrimidine Inhibitors Using a Focused Library and Structure-Based Optimization Approach (2012)

A novel class of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2) inhibitors was discovered through screening a kinase-focused library. A homology model of MAPKAP-K2 was generated and used to guide the initial SAR studies and to rationalize the observed selectivity over CDK2. An X-ray crystal structure of a compound from the active series bound to crystalline MAPKAP-K2 confirmed the predicted binding mode. This has enabled the discovery of a series of pyrazolo[1,5-a]pyrimidine derivatives showing good in vitro cellular potency as anti-TNF-α agents and in vivo efficacy in a mouse model of endotoxin shock.
MPSoC Architecture for Macro Blocks Line Partitioning of H.264/AVC Encoder (2014)

Using multiprocessor technology is an interesting solution for reducing the processing time of complex video encoders such as H.264/Advanced Video Coding (AVC). This paper details different levels of parallelism presented in related works for H.264/AVC encoder. An efficient Macro Blocks Line level parallelism for the intra prediction encoding chain of H.264/AVC for High Definition (HD) video is proposed. It is implemented on MPSoC architecture using an open and free platform for virtual prototyping named SoCLib. Comparing to related works, the proposed partitioning meets strongly the size of required memory constraint and provides an interesting speed-up. The proposed architecture is based on three processors and ensures a reduced circuit area. Experimental results reveal a run time saving of about 59.8% in terms of processing speed, compared to a classical execution based on a single CPU, without affecting the quality of the reconstructed video. Using multiprocessor technology is an interesting solution for reducing the processing time of complex video encoders such as H.264/Advanced Video Coding (AVC). This paper details different levels of parallelism presented in related works for H.264/AVC encoder. An efficient Macro Blocks Line level parallelism for the intra prediction encoding chain of H.264/AVC for High Definition (HD) video is proposed. It is implemented on MPSoC architecture using an open and free platform for virtual prototyping named SoCLib. Comparing to related works, the proposed partitioning meets strongly the size of required memory constraint and provides an interesting speed-up. The proposed architecture is based on three processors and ensures a reduced circuit area. Experimental results reveal a run time saving of about 59.8% in terms of processing speed, compared to a classical execution based on a single CPU, without affecting the quality of the reconstructed video.
Betriebsfestigkeit und Zuverlässigkeit von komplexen und intelligenten Strukturen (2003)

Abstract Die Betriebsfestigkeit und Zuverlässigkeit einer Konstruktion ist nur durch sorgfältige Bemessung zu erreichen. Dabei sind die aus den Einsatzprofilen stammenden unterschiedlichen Anforderungen an die Festigkeit der Bauteile zu berücksichtigen. Um einerseits alle Einflüsse aus Belastung, Werkstoff, Herstellungsprozess, örtlicher Geometrie zu erfassen und andererseits Forderungen bezüglich der Konkurrenzfähigkeit zu erfüllen, muss der Konstrukteur effiziente Methoden anwenden, mit denen Betriebsfestigkeit und Zuverlässigkeit gewährleistet werden. Heute steht im Entwicklungsprozess einer Konstruktion die Verringerung der Markteinführungszeit im Vordergrund. Dies erfordert den vermehrten Einsatz numerischer Methoden (Simulation des dynamischen Systemverhaltens, der Bauteileigenschaften und der örtlichen Spannungen), um den Aufwand der experimentellen Vorgehensweise für Optimierung und Nachweis zu reduzieren. In Zukunft werden immer mehr Konstruktionsteile von mechatronischen und sogar multifunktionalen Komponenten ersetzt. Kenntnisse des Systemverhaltens sowie der gegenseitigen Beeinflussung von elektronischer Steuerung und mechanischem Verhalten sind erforderlich, um die Zuverlässigkeit dieser Entwicklung zu bewerten.
An Ultrasonic-EMG Transducer for Biodynamic Research (1978)

This note describes a newly developed single-element muscle action potential/motion transducer. The transcuer was specially designed for speech research. Techniques for use of the transducer are described. Sample data are presented illustrating the capability of the transducer, and applications of the device are discussed.
From Th-Rhabdophane to Monazite-Cheralite Solid Solutions: Thermal Behavior of Nd1–2xThxCaxPO4·nH2O (x = 0–0.15) (2019)

The synthesis and thermal behavior of Nd1–2xThxCaxPO4·nH2O (x = 0–0.15) solid solutions crystallizing in the rhabdophane structure type were studied by combining in situ high-temperature powder X-ray diffraction (HT-PXRD), thermogravimetric analysis, and dilatometry techniques. The samples prepared under hydrothermal conditions (T = 110 °C, t = 4 days) were found to follow the same dehydration process as the NdPO4·0.667H2O end-member. The temperature of maximum dehydration rate slightly increased from 210 ± 3 °C to 214 ± 3 °C with the Ca–Th coupled substitution rate. In parallel, the evolution of the unit cell parameters was also monitored by collecting in situ HT-PXRD data. The phase transition into the monazite-type structure occurred at a higher temperature (from 650 to 850 °C) and was correlated to a temperature of maximum linear shrinkage rate increasing from 693 ± 1 °C to 762 ± 1 °C with the Ca–Th content. Therefore, the process of conversion leading to the stabilization of Nd1–2xThxCaxPO4 was successfully achieved.
Strong viral associations with SLE among Filipinos (2017)

Filipino patients with SLE have elevated prevalence and concentrations of antibodies against EBV, CMV, HSV-1 and HSV-2 antigens, along with altered anti-EBNA-1 specificities. EBV reactivation is more common among Filipino patients with SLE compared with healthy Filipinos and may contribute to SLE pathogenesis in this population.
Translational strategy using multiple nuclear imaging biomarkers to evaluate target engagement and early therapeutic efficacy of SAR439859, a novel selective estrogen receptor degrader (2020)

In our preclinical studies, dose-dependent inhibition of FES tumoral uptake confirmed target engagement of SAR439859 to ERα. FES-PET thus appears as a relevant imaging biomarker for measuring non-invasively the impact of SAR439859 on tumor estrogen receptor occupancy. This study further validates the use of FLT-PET to directly visualize the anti-proliferative tumor effect of the palbociclib CDK 4/6 inhibitor alone and in combination with SAR439859.
Message from the editor- in-chief - Special issue: modulation, coding, and signal processing in wireless networks (2005)

Presents the editorial for this issue of the publication.
In Vitro Evaluation of Lipid Matrices for the Development of a Sustained-Release Sulfamethazine Bolus for Lambs (1996)

The aim of this study is the development of a high-density bolus to be given to lambs in order to release sulfamethazine during 4 days after a single oral administration. The suitability of 12 lipid matrix formulations was assessed in order to maintain the integrity of the tablet even after complete dissolution of the active substance. The influence of both nature and concentration of the lipid excipient on the in vitro release of sulfamethazine was investigated. The influences of the granulation method and of the compression force were assessed on a formulation containing taining Cutinaδ HR as a binding and sustained-release agent. Finally, stability tests showed that the in vitro release characteristics remain unchanged during storage.
La grotte de Casamène à Besançon (Doubs) gisement du Paléolithique moyen (1975)

Petrequin Pierre, Piningre Jean-François, Urlacher J. P., Petiot Robert, Prat François. La grotte de Casamène à Besançon (Doubs) gisement du Paléolithique moyen. In: Gallia préhistoire, tome 18, fascicule 2, 1975. pp. 359-399.
Deep k-Means: Re-Training and Parameter Sharing with Harder Cluster Assignments for Compressing Deep Convolutions (2018)

The current trend of pushing CNNs deeper with convolutions has created a pressing demand to achieve higher compression gains on CNNs where convolutions dominate the computation and parameter amount (e.g., GoogLeNet, ResNet and Wide ResNet). Further, the high energy consumption of convolutions limits its deployment on mobile devices. To this end, we proposed a simple yet effective scheme for compressing convolutions though applying k-means clustering on the weights, compression is achieved through weight-sharing, by only recording $K$ cluster centers and weight assignment indexes. We then introduced a novel spectrally relaxed $k$-means regularization, which tends to make hard assignments of convolutional layer weights to $K$ learned cluster centers during re-training. We additionally propose an improved set of metrics to estimate energy consumption of CNN hardware implementations, whose estimation results are verified to be consistent with previously proposed energy estimation tool extrapolated from actual hardware measurements. We finally evaluated Deep $k$-Means across several CNN models in terms of both compression ratio and energy consumption reduction, observing promising results without incurring accuracy loss. The code is available at this https URL
Bacterial Biofilms on Implanted Suture Material Are a Cause of Surgical Site Infection (2014)

Bacterial biofilms on implanted suture material can manifest as persistent surgical site infections that require complete removal of the underlying foreign body substrata for resolution.
Radiation Environment of Mangrove Pneumatophores in Brackish Water. (1996)

The pneumatophores of Avicennia and Sonneratia species photosynthesize and the photosynthetically generated O2 is used for the respiration in the roots in subsoil. To understand the radiation environment of the pneumatophores, we measured solar radiation on the vertical surface (Rv) in the water with dye films. The Rv averaged over the daytime at a depth of 30 cm was similar to the light compensation points in the pneumatophores. From this result, it can be supposed that the photosynthesis nearly compensated the respiration at a depth of 30 cm and supplied O2 to the roots in subsoil at shallower places, even when the pneumatophores were submerged in the daytime.
Labeling of Extracellular Vesicles for Monitoring Migration and Uptake in Cartilage Explants (2021)

Extracellular vesicles (EVs) are used in different studies to prove their potential as a cell-free treatment due to their cargo derived from their cellular source, such as platelet lysate (PL). When used as treatment, EVs are expected to enter the target cells and effect a response from these. In this research, PL-derived EVs have been studied as a cell-free treatment for osteoarthritis (OA). Thus, a method was set up to label EVs and test their uptake on cartilage explants. PL-derived EVs are labeled with the lipophilic dye PKH26, washed twice through a column, and then tested in an in vitro inflammation-driven OA model for 5 h after particle quantification by nanoparticle tracking analysis (NTA). Hourly, cartilage explants are fixed, paraffined, cut into 6 µm sections to mount on slides, and observed under a confocal microscope. This allows verification of whether EVs enter the target cells (chondrocytes) during this period and analyze their direct effect.
GSS for presentation support (2000)

Supercharging the audience through simultaneous discussions during presentations.
Serious infections in a population‐based cohort of 86,039 seniors with rheumatoid arthritis (2012)

Seniors with RA have significant morbidity related to serious infections, which exceeds previous reports among younger RA populations. Rural residence, higher comorbidity, markers of disease severity, and previous infection were associated with serious infections in seniors with RA. Our results emphasize that many RA drugs may increase the risk of infection, but glucocorticoids appear to confer a particular risk.
Long-term Outcomes of Lyme Disease (2000)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
The aromatic nature of residue 66 of the 11‐kDa subunit of ubiquinol‐cytochrome c oxidoreductase of the yeast Saccharomyces cerevisiae is important for the assembly of a functional enzyme (1994)

Transformation of multi- and single-copy plasmids carrying a mutated version (LTN2, region 66-YWYWW-70 replaced by SASAA) of QCR8, the gene encoding the 11-kDa subunit ubiquinol-cytochrome c oxidoreductase of Saccharomyces cerevisiae, to a QCR8(0) strain indicated the importance of this aromatic region for the assembly of a functional enzyme. Sequencing of plasmids giving spontaneous restoration of growth to some colonies among the single-copy LTN2 transformants showed that changing the sequence SASAA into the sequence FASAA could, to a large extent, overcome the observed assembly defect, indicating the importance of the aromatic nature of residue 66.
Synthesis, growth and characterization of single crystals of pure and thiourea doped L‐glutamic acid hydrochloride (2006)

Abstract L(+)Glutamic acid hydrochloride [HOOC (CH 2 ) 2 CH(NH 2 ) COOH·HCl], a monoamino dicarboxylic acid salt of L‐Glutamic acid was synthesized and the synthesis was confirmed by FTIR analysis. Solubility of the material in water was determined. Pure and Thiourea doped L‐Glutamic acid hydrochloride crystals were grown by low temperature solution growth using solvent evaporation technique. XRD, UV‐Vis‐NIR analyses were carried out for both pure and thiourea doped crystals. The crystals were qualitatively analyzed by EDAX analysis and the presence of thiourea was confirmed. The cell parameters of L‐Glutamic acid hydrochloride have been determined as a = 5.151 Å, b = 11.79 Å, c = 13.35 Å by X‐ray diffraction analysis and it crystallizes in orthorhombic space group P2 1 2 1 2 1 . UV‐Vis‐NIR spectra analysis showed good optical transmission in the entire visible region for both pure and doped crystals. Micro hardness of both pure and doped crystals has been determined using Vickers micro hardness tester. The SHG efficiencies of both pure and doped crystals were determined using Kurtz powder test and pure L‐Glutamic acid hydrochloride crystal was found to possess better efficiency than thiourea doped L‐Glutamic acid hydrochloride crystals. (© 2007 WILEY‐VCH Verlag GmbH &amp; Co. KGaA, Weinheim)
“Oh, it is you, is it?”: Closing the Door on Reasonable Resistance to Unlawful Police Entry in Indiana (2013)

For over a century, Indiana residents could lawfully resist police officers who tried to enter their homes illegally. 1On May 12, 2011, in Barnes v. State, 2 the Indiana Supreme Court parted from the common law and stripped Hoosiers of their right to reasonably resist unlawful police entries. 3 The court granted a petition for rehearing on September 20, 2011, and "restated" its holding: Hoosiers can reasonably resist, but battery on a police officer is not reasonable resistance. 4 Then, on March 20, 2012, Governor Mitch Daniels signed into law a bill "reaffirming the long standing right of a citizen to protect his or her home against unlawful intrusion." 5Homeowners may use "reasonable force" to prevent unlawful police entry, but the statute does not define "reasonable force." 6 This Note argues that the Indiana Supreme Court blocked any effective means to resist unlawful police home entry when it prohibited Hoosiers from resisting with force that would constitute battery.The Indiana General Assembly was correct to codify the common-law castle doctrine.But the revised statute does not remedy the court's limitation of reasonable resistance because it does not define "reasonable force."Without any guidance from the legislature, the level of resistance that is reasonable to prevent unlawful police entry will be left to the judiciary.
A self-aligned 1-&#181;m-channel CMOS technology with retrograde n-well and thin epitaxy (1985)

A six-mask 1-µm CMOS process with many self-aligned features is described. It uses a thin p-type epitaxial layer on a p <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">+</sup> substrate and a retrograde n-well. Self-aligned TiSi <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> is formed on n <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">+</sup> and p <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">+</sup> diffusions to reduce the sheet resistance and to make butted source contacts. It is shown that n <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">+</sup> poly-gated p-channel devices can be properly designed with low threshold magnitudes and good turn-off characteristics. With a 5-V supply, the minimum gate delay of unloaded CMOS ring oscillators is 150 ps/stage. Furthermore, it is demonstrated that this CMOS technology is latchup free since the holding voltage for latchup is higher than 5 V.
UAV-Based Thermal Imagery for Detecting Varietal Differences in Cotton (2021)

Earth and Space Science Open Archive Presented WorkOpen AccessYou are viewing an older version [v1]Go to new versionUAV-Based Thermal Imagery for Detecting Varietal Differences in CottonAuthorsSebastianCallejaiDEmmanuelGonzaleziDDukePauliSee all authors Sebastian CallejaiDCorresponding Author• Submitting AuthorUniversity of ArizonaiDhttps://orcid.org/0000-0001-9401-4494view email addressThe email was not providedcopy email addressEmmanuel GonzaleziDUniversity of ArizonaiDhttps://orcid.org/0000-0002-3021-9842view email addressThe email was not providedcopy email addressDuke PauliUniversity of Arizonaview email addressThe email was not providedcopy email address
DMAP-assisted sulfonylation as an efficient step for the methylation of primary amine motifs on solid support (2017)

Several multistep strategies were developed to ensure single methylation of amines on solid support. These strategies rely on the introduction of the <i>o</i>-NBS protecting/activating group as a key step. We found that the state-of-the-art strategies fail for the methylation of several primary amine motifs, largely due to inefficient sulfonylation. Here we show that using the superior nucleophilic base DMAP instead of the commonly used base collidine as a sulfonylation additive is essential for the introduction of the <i>o</i>-NBS group to these amine motifs. DFT calculations provide an explanation by showing that the energy barrier of the DMAP intermediate is significantly lower than the one of the collidine. We demonstrate that using DMAP as a sole additive in the sulfonylation step results in an overall effective and regioselective <i>N</i>-methylation. The method presented herein proved highly efficient in solid-phase synthesis of a somatostatin analogue bearing three <i>N</i><sup>α</sup>-methylation sites that could not be synthesized using the previously described state-of-the-art methods.
A RIS/PACS simulator with web-based image distribution and display system for education (2004)

As PACS and related imaging technologies become more common in the healthcare setting, better methods are needed for training radiologists, allied healthcare and IT providers to understand and use them effectively. We presented a PACS Simulator in 2002 and a RIS integrated PACS Simulator in 2003. In this presentation we integrate a web-based image distribution and display system with the Simulator to complete the simulation of clinical PACS workflow. The Simulator consists of RIS Simulator, modality Simulator, DICOM gateway, PACS controller, clinical viewing workstations, PACS monitor system and a web server. The addition web server distributes images to browser-based display clients for display and manipulation using web technology. Using this Simulator, trainees can: (1) Observe RIS/PACS operation with web image distribution, component by component, (2) Trace image data flow through each component, (3) Query, retrieve and review images at web display clients, (4) Induce failure in a component to observe its impact on the entire RIS/PACS operation. The Simulator has been developed as a stand-alone tool for trainees to understand RIS/PACS concept and appreciate RIS/PACS workflow with hands-on experience. The Simulator has been applied in many training classes, and the addition of web server will significantly improve its training value.