gebhart/patrepeval huggingface dataset:
EFFECTS OF ANTIBIOTIC THERAPY ON THE APPEARANCE OF THE ABNORMAL MICTURITION REFLEX AFTER SPINAL CORD INJURY IN RATS (2008)

You have accessJournal of Urology1 Apr 2008EFFECTS OF ANTIBIOTIC THERAPY ON THE APPEARANCE OF THE ABNORMAL MICTURITION REFLEX AFTER SPINAL CORD INJURY IN RATS Dong Broqueres-You, Delphine Behr-Roussel, Stephanie Oger, Pierre Denys, Laurent Alexandre, and Francois A Giuliano Dong Broqueres-YouDong Broqueres-You , Delphine Behr-RousselDelphine Behr-Roussel , Stephanie OgerStephanie Oger , Pierre DenysPierre Denys , Laurent AlexandreLaurent Alexandre , and Francois A GiulianoFrancois A Giuliano View All Author Informationhttps://doi.org/10.1016/S0022-5347(08)61020-4AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "EFFECTS OF ANTIBIOTIC THERAPY ON THE APPEARANCE OF THE ABNORMAL MICTURITION REFLEX AFTER SPINAL CORD INJURY IN RATS." The Journal of Urology, 179(4S), pp. 348–349 © 2008 by American Urological AssociationFiguresReferencesRelatedDetails Volume 179Issue 4SApril 2008Page: 348-349 Advertisement Copyright & Permissions© 2008 by American Urological AssociationMetricsAuthor Information Dong Broqueres-You More articles by this author Delphine Behr-Roussel More articles by this author Stephanie Oger More articles by this author Pierre Denys More articles by this author Laurent Alexandre More articles by this author Francois A Giuliano More articles by this author Expand All Advertisement PDF downloadLoading ...
A Robust Metal‐Organic Framework with Scalable Synthesis and Optimal Adsorption and Desorption for Energy‐Efficient Ethylene Purification (2023)

Abstract Adsorptive separation is an energy‐efficient alternative, but its advancement has been hindered by the challenge of industrially potential adsorbents development. Herein, a novel ultra‐microporous metal‐organic framework ZU‐901 is designed that satisfies the basic criteria raised by ethylene/ethane (C 2 H 4 /C 2 H 6 ) pressure swing adsorption (PSA). ZU‐901 exhibits an “S” shaped C 2 H 4 curve with high sorbent selection parameter (65) and could be mildly regenerated. Through green aqueous‐phase synthesis, ZU‐901 is easily scalable with 99 % yield, and it is stable in water, acid, basic solutions and cycling breakthrough experiments. Polymer‐grade C 2 H 4 (99.51 %) could be obtained via a simulating two‐bed PSA process, and the corresponding energy consumption is only 1/10 of that of simulating cryogenic distillation. Our work has demonstrated the great potential of pore engineering in designing porous materials with desired adsorption and desorption behavior to implement an efficient PSA process.
Ultrasound‐mediated therapies using oil and perfluorocarbon‐filled nanodroplets (2006)

Abstract Over the past decade, nanotechnology has emerged as a research tool with applications in virtually all areas of science ranging from the computer industry to biotechnology. With respect to the latter, nanoparticles, or solid nanometer‐sized bodies, have been incorporated into biotechnology as drug‐delivery agents. We have developed a novel variant of the biotechnology, however, designing targeted, oil and perfluorocarbon‐filled, malleable nanodropets that are able to carry therapeutics selectively to areas of disease. In order to help facilitate delivery, we have combined this technology with ultrasound to aid and enhance the delivery of drug payloads via these nanodroplets, thereby increasing effective delivery of therapeutic and minimizing systemic toxicity effects. Drug Dev. Res. 67:42–46, 2006. © 2006 Wiley‐Liss, Inc.
Application of nanotechnology in agriculture, postharvest loss reduction and food processing: food security implication and challenges (2021)

Ensuring food security in developing countries is highly challenging due to low productivity of the agriculture sector, degradation of natural resources, high post farming losses, less or no value addition, and high population growth. Researchers are striving to adopt newer technologies to enhance supply to narrow the food demand gap. Nanotechnology is one of the promising technologies that could improve agricultural productivity via nano fertilizers, use of efficient herbicides and pesticides, soil feature regulation, wastewater management, and pathogen detection. It is equally beneficial for industrial food processing with enhanced food production with excellent market value, elevated nutritional and sensing property, improved safety, and better antimicrobial protection. Nanotechnology can also reduce post-farming losses by increasing the shelf life with the aid of nanoparticles. However, further investigation is required to solve the safety and health risks associated with the technology.
Structural evolution of an organic/inorganic oxide glass studied by differential scanning calorimetry and mechanical spectroscopy (1992)

Organic/inorganic 3-(trimethoxysilyl)propyl methacrylate/SiO 2 based glass was synthesized by sol-gel process. One objective of the present work was to study the evolution of microstructure and mechanical properties during transformation from hybrid alcogel to hybrid glass. Results of measurements about physical properties have been obtained by mechanical tests. Microstructural investigation methods such as DSC and Mechanical Spectroscopy were used to get more informations about molecular network behaviour with thermal treatments. This paper shows that physical properties depend on time because of relaxation effects. These ones have to be measured with a well controlled synthesis chemistry to reach a defined structural state.
Performance of the Wideband Massive Uplink MIMO with One-Bit ADCs (2016)

Analog-to-digital converters (ADCs) consume a significant part of the total power in a massive MIMO base station. One-bit ADCs are one way to reduce power consumption. This paper presents an analysis of the spectral efficiency of single-carrier and OFDM transmission in massive MIMO systems that use one-bit ADCs. A closed-form achievable rate is derived for a wideband system with a large number of channel taps, assuming linear channel estimation and symbol detection. Quantization results in two types of error in the symbol detection. The circularly symmetric error becomes Gaussian in massive MIMO and vanishes as the number of antennas grows. The amplitude distortion, which severely degrades the performance of OFDM, is caused by variations in received interference energy between symbol durations. As the number of channel taps grows, the amplitude distortion vanishes and OFDM has the same performance as single-carrier transmission. A main conclusion of this paper is that wideband massive MIMO systems work well with one-bit ADCs.
Interaction of Metal Bis(Phosphane) Fragments with Phosphirene and Phosphirane Complexes (1987)

Abstract Different types of interactions of platinum, palladium and nickel complexes with phosphirene and phosphirane rings are presented and discussed.
3D interactive tractography-informed resting-state fMRI connectivity (2015)

In the past decade, the fusion between diffusion magnetic resonance imaging (dMRI) and functional magnetic resonance imaging (fMRI) has opened the way for exploring structure-function relationships in vivo. As it stands, the common approach usually consists of analysing fMRI and dMRI datasets separately or using one to inform the other, such as using fMRI activation sites to reconstruct dMRI streamlines that interconnect them. Moreover, given the large inter-individual variability of the healthy human brain, it is possible that valuable information is lost when a fixed set of dMRI/fMRI analysis parameters such as threshold values are assumed constant across subjects. By allowing one to modify such parameters while viewing the results in real-time, one can begin to fully explore the sensitivity of structure-function relations and how they differ across brain areas and individuals. This is especially important when interpreting how structure-function relationships are altered in patients with neurological disorders, such as the presence of a tumor. In this study, we present and validate a novel approach to achieve this: First, we present an interactive method to generate and visualize tractography-driven resting-state functional connectivity, which reduces the bias introduced by seed size, shape and position. Next, we demonstrate that structural and functional reconstruction parameters explain a significant portion of intra- and inter-subject variability. Finally, we demonstrate how our proposed approach can be used in a neurosurgical planning context. We believe this approach will promote the exploration of structure-function relationships in a subject-specific aspect and will open new opportunities for connectomics.
Streaming End-to-end Speech Recognition For Mobile Devices (2018)

End-to-end (E2E) models, which directly predict output character sequences given input speech, are good candidates for on-device speech recognition. E2E models, however, present numerous challenges: In order to be truly useful, such models must decode speech utterances in a streaming fashion, in real time; they must be robust to the long tail of use cases; they must be able to leverage user-specific context (e.g., contact lists); and above all, they must be extremely accurate. In this work, we describe our efforts at building an E2E speech recognizer using a recurrent neural network transducer. In experimental evaluations, we find that the proposed approach can outperform a conventional CTC-based model in terms of both latency and accuracy in a number of evaluation categories.
Combination of evidence in rough set theory (2002)

Studies the knowledge refinement resulting from the accumulation of evidence in rough set theory. Some of the important and practical issues, such as the use of different sample spaces, are discussed. This new concept of evidence accumulation broadens the framework of rough sets for the further development of intelligent information systems.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Morphology and Growth of Arthrospira platensis during Cultivation in a Flat-Type Bioreactor (2021)

<i>Arthrospira platensis</i> (AP) is a cyanobacterium with a high economic value and is nowadays one of the most important industrially cultivated microalgae. Knowledge of its growth is essential for the understanding of its physiology and yield. The growth of AP biomass occurs through two mechanisms: (1) propagation by fragmentation of trichomes, and (2) the trichomes are extended by binary fission until they reach their mature status. These phases are visualized by live cell light and laser scanning microscopy, demonstrating the different phases of AP growth.
When, how, and what cell source for hematopoietic cell transplantation in first complete remission adult acute lymphoblastic leukemia? (2012)

Abstract Adult acute lymphoblastic leukemia (ALL) is a heterogeneous disease affected by many patient- and disease-related factors, including age, immunologic subtype, and clinical, genetic, and molecular features. Allogeneic hematopoietic cell transplantation (HCT) has occupied an increasing therapeutic role as a result of significant improvements in supportive care and histocompatibility testing. ALL Philadelphia chromosome–negative patients formerly excluded now are considered HCT candidates and survival rates with alternative donors may approach those obtained with matched-related donors. Reduced-intensity conditioning rather than myeloablative conditioning appears to provide comparable patient outcome results although these observations have not been validated in prospective studies. Improved tools can identify patients thought to be in remission based on morphology but who have active disease at the molecular or immunophenotypic level (minimal residual disease). Using B-cell antigen panels, clone-specific immunoglobulins, or T-cell receptor rearrangements to detect positivity at thresholds of at least 1 in 104 cells, such patients may be taken to HCT. The ongoing advances in conventional therapy intensity, however, now yield improved results and ongoing reassessment of the place of HCT needs to be continued; every effort should be made to enroll eligible patients in clinical trials.
Synthesis of a 99mTc-labeled substance P derivative for detection of glioblastoma tumors (2012)

Background and Aims: Malignant gliomas are the most common primary brain tumors in adults with a high mortality risk and still associated with a poor prognosis despite advances in medical sciences. Neurokinin1 receptors (NK1R) are over expressed in all malignant glioma stages including astrocytomas (grade I/II/IIII) and glioblastoma (grade IV). The distribution density of NK1R correlates with the degree of malignancy as well. Substance P (SP) is a member of tachykinin family neuropeptides with specific affinity for NK1R. This study investigated the labeling of a SP analog with 99mTc for imaging of NK1R positive tissues. Methods: A modified derivative of SP was designed and synthesized using a standard F-moc strategy. The crude peptide was purified by semi-preparative RP-HPLC method and then characterized by analytical HPLC and LC/Mass. The purified peptide was labeled with 99mTc on its specified conjugation site. Labeling yield and radiochemical analysis were performed by ITLC and HPLC methods equipped with a gamma detector. The stability of radiopeptide was checked in the presence of human serum at 37 oC in 24 h periods. Biodistribution of radiopeptide was studied on normal mice and the NK1R binding internalization and externalization rates were studied in human glioblastoma cell lines. Results: A labeling yield of >95% was obtained and peptide conjugate showed good stability in human serum in vitro. An acceptable specific binding to cell lines was observed (15 ± 60 % at 4 h). In vivo distribution studies in normal mice showed a low uptake in bone, liver, blood and muscles. A high uptake was occurred in kidneys, intestine, colon and salivary glands. Conclusions: This study could promote the peptide receptor radiation therapy (PRRT) for Gliobelastomas by 186/188Re or 131I labeled SP analogs in the future.
Merging Source and Shared Trees Multicast in MPLS Networks (2006)

Multicast and MPLS are two complementary technologies. Merging MPLS and multicast technologies can acquire two advantages: multicast saving bandwidth and MPLS supporting high-speed, QoS and traffic engineering, VPN. Implementation of MPLS multicast has two key expectations: how to construct multicast tree over MPLS domain and how to enhance multicast scalability. In this paper, we design a scalable MPLS multicast algorithm. The algorithm uses tunneling technology and branching nodes technology, which can merge source and shared trees multicast in MPLS networks. Using tunneling technology to implement multipoint-to-multipoint (MP2MP) shared-tree multicast can solve one of the difficulties of MPLS multicast: MP2MP label distribution. Using branching nodes technology can reduce multicast forwarding state in routers and enhance multicast scalability. We also evaluate our proposal in terms of scalability and efficiency and present some simulation results based on NS-2
Andere Abkürzungen (2007)

No AccessBeständigkeit von KunststoffenSep 2007Andere AbkürzungenGottfried Wilhelm Ehrenstein, Sonja PongratzGottfried Wilhelm Ehrenstein, Sonja Pongratzhttps://doi.org/10.3139/9783446411494.007SectionsAboutPDF ToolsAdd to FavoritesDownload CitationTrack CitationsCopy LTI LinkPDF key 'share (en)' returned an object instead of string.FacebookTwitterEmailLinkedIn previous chapternext chapter FiguresReferencesRelatedDetails 2007Pages: 886-888Print ISBN: 978-3-446-21851-2eISBN: 978-3-446-41149-4 Copyright & Permissions© 2007 Carl Hanser Verlag GmbH & Co. KGPDF downloadLoading ...
Treatment with Thyrotropin-Releasing Hormone (TRH) in Patients with Traumatic Spinal Cord Injuries (1995)

Numerous preclinical studies have demonstrated that posttraumatic treatment of spinal cord injury (SCI) with thyrotropin-releasing hormone (TRH) or TRH analogs improves long-term behavioral recovery. The purpose of the present study is to provide preliminary data regarding the safety and potential efficacy of TRH in patients with acute SCI. A total of 20 patients with SCI were classified by clinical examination into complete and incomplete injury groups within 12 h of trauma and randomly assigned in double-blinded fashion to treatment with either TRH (0.2 mg/kg intravenous bolus followed by 0.2 mg/kg/h infusion over 6 h) or vehicle (equal volume physiological saline) placebo. A variety of physiological variables were followed during treatment. Clinical examination included motor and sensory testing, as well as assigning a Sunnybrook score based upon level of function. Patients were examined at 24 h, 72 h, 1 week, 1 month, 4 months, and 12 months after injury. TRH infusions were well tolerated. There appeared to be no discernible treatment effect in patients with complete injuries although data were available from only six such patients at 4 months. For the incomplete injury group, a total of 6 treated and 5 placebo patients had 4-month evaluations. TRH treatment was associated with significantly higher motor, sensory, and Sunnybrook scores than placebo treatment. Because of patients lost to subsequent follow-up, 12-month data were not highly informative. These observations must be interpreted with considerable caution because of the small patient numbers, but together with extensive animal studies they support the need for a larger multicenter clinical trial of TRH.
Study of the electrospray ionization tandem mass spectrometry of sildenafil derivatives (2002)

A detailed analysis of the product ion spectrum generated from the protonated molecule of sildenafil (Viagra(R)) under multiple tandem mass spectrometry (ESI-MS(n)) conditions using an ion-trap mass spectrometer is reported. Molecular composition data of the fragment ions were obtained with the aid of comparisons of the multiple tandem mass spectra of eight sildenafil derivatives in two series, the structures of which are identical except for some substituted alkyl groups. Attempts have been made to provide rational pathways for the formation of the fragment ions from these protonated sildenafil derivatives. The structure-fragmentation relationships will facilitate the characterization of the structures of other sildenafil analogs.
A random walk model that accounts for space occupation and movements of a large herbivore (2021)

Animal movement has been identified as a key feature in understanding animal behavior, distribution and habitat use and foraging strategies among others. Large datasets of invididual locations often remain unused or used only in part due to the lack of practical models that can directly infer the desired features from raw GPS locations and the complexity of existing approaches. Some of them being disputed for their lack of biological justifications in their design. We propose a simple model of individual movement with explicit parameters, based on a two-dimensional biased and correlated random walk with three forces related to advection (correlation), attraction (bias) and immobility of the animal. These forces can be directly estimated using individual data. We demonstrate the approach by using GPS data of 5 red deer with a high frequency sampling. The results show that a simple random walk template can account for the spatial complexity of wild animals. The practical design of the model is also verified for detecting spatial feature abnormalities and for providing estimates of density and abundance of wild animals. Integrating even more additional features of animal movement, such as individuals' interactions or environmental repellents, could help to better understand the spatial behavior of wild animals.
The Generalized Pairs Plot (2012)

This article develops a generalization of the scatterplot matrix based on the recognition that most datasets include both categorical and quantitative information. Traditional grids of scatterplots often obscure important features of the data when one or more variables are categorical but coded as numerical. The generalized pairs plot offers a range of displays of paired combinations of categorical and quantitative variables. A mosaic plot, fluctuation diagram, or faceted bar chart may be used to display two categorical variables. A side-by-side boxplot, stripplot, faceted histogram, or density plot helps visualize a categorical and a quantitative variable. A traditional scatterplot is suitable for displaying a pair of numerical variables, but options also support density contours or annotating summary statistics such as the correlation and number of missing values, for example. By combining these, the generalized pairs plot may help to reveal structure in multivariate data that otherwise might go unnoticed in the process of exploratory data analysis. Two different R packages provide implementations of the generalized pairs plot, gpairs and GGally. Supplementary materials for this article are available online on the journal web site.
Proposition pour la modélisation d'applications ubiquitaires (2006)

National audience
Enzymatic Syntheses of Selenium-Containing Tryptophan Analogs Using Tryptophan Synthase and Their Bioincorporation into Lignin Peroxidase (2024)

Abstract Not Provided
Structural requirements of steroidal agonists of transient receptor potential melastatin 3 (TRPM3) cation channels (2013)

Our data demonstrate that nifedipine and pregnenolone sulphate act at different binding sites when activating TRPM3. The latter activates TRPM3 by binding to a chiral and thus proteinaceous binding site, as inferred from the differential effects of the enantiomers. The double bond between position C5 and C6 of pregnenolone sulphate is not strictly necessary for the activation of TRPM3 channels, but a negative charge at position C3 of the steroid is highly important. These results provide a solid basis for understanding mechanistically the rapid chemical activation of TRPM3 channels.
Robust tracking of human hand postures for robot teaching (2011)

To enable the creation of manual interaction databases, aiding the replication of dexterous capabilities with anthropomorphic robot hands by utilizing information about how humans perform complex manipulation tasks, requires the capability to record and analyze large amounts of manual interaction sequences. For this goal we have studied and compared three mappings from captured human hand motion data to a simulated model, which allow for robust and accurate real-time hand posture tracking. We evaluate the effectiveness of these mappings and discuss their pros and cons in various real-world scenarios. The first method is based on data glove data and aims for direct gaging of hand joints. The other two methods utilize a VICON motion tracking system which monitors markers placed on all finger segments. Here we compare two approaches: a direct computation of hand postures from angles between adjacent markers and an iterative inverse kinematics approach to optimally reproduce fingertip positions. For a quantitative evaluation, we employ a “calibration objects” technique to obtain a reliable ground truth of task-relevant hand posture data.
Multi-task learning for boosting with application to web search ranking (2010)

In this paper we propose a novel algorithm for multi-task learning with boosted decision trees. We learn several different learning tasks with a joint model, explicitly addressing the specifics of each learning task with task-specific parameters and the commonalities between them through shared parameters. This enables implicit data sharing and regularization. We evaluate our learning method on web-search ranking data sets from several countries. Here, multitask learning is particularly helpful as data sets from different countries vary largely in size because of the cost of editorial judgments. Our experiments validate that learning various tasks jointly can lead to significant improvements in performance with surprising reliability.