gebhart/patrepeval huggingface dataset:
Emotional Changes in the Process of Relief of Tension (1998)

(1) How subjective emotional changes occur in the process of the relief of tension and (2) whether these changes depend on the disposition of the tension-causing events were examined. Tension-causing events were classified into pleasant events and aversive ones. In order to rate emotion which subjects experienced at the tension-causing events, subjects were asked to draw curves on a questionnaire. The results showed that the levels of tension in both categories increased until the start of the event, decreased during the event and still further after the event. In the aversive events, the amplitude of the change was greater than that in the pleasant events. After aversive events were over, shifts toward opposite direction from tension to relaxation and from unpleasantness to pleasantness could be observed, while not in the favorable events. In conclusion, this study suggested that the emotional changes in the process of the relief of tension depend partly on the disposition of tension-causing events. The disposition of events influences to the amplitude and the shifts toward opposite direction of emotional changes.
A merged process for thick single-crystal Si resonators and BiCMOS circuitry (1999)

A simple process has been developed which combines thick single-crystal Si micromechanical devices with a bipolar complimentary metal-oxide-semiconductor (BiCMOS) integrated circuit process. This merged process allows the integration of Si mechanical resonators as thick as 11 /spl mu/m with any integrated circuit process with the addition of only a single masking step. The process does not require the use of Si on insulator wafers or any type of wafer bonding. The Si resonators were etched in an inductively coupled plasma source which allowed deep trenches to be fabricated with high aspect ratios and smooth sidewall surfaces. Clamped-clamped beam Si resonators that were 500 /spl mu/m long, 5 /spl mu/m wide, and 11 /spl mu/m thick have been fabricated and tested. A typical resonator had a resonance frequency of 28.9 kHz and a maximum amplitude of vibration at resonance of 4.6 /spl mu/m in air. The average measured resonance frequency across a 4-in-diameter Si wafer was within 0.5% of that predicted by theory. Working NMOS transistors were fabricated and tested on the same chip as the resonator with measured threshold voltages of 0.6 V and an output conductance of 2.0/spl times/10/sup -5/ /spl Omega//sup -1/ for a gate voltage of 4 V.
How Do PROMIS Scores Correspond to Common Physical Abilities? (2021)

The visual explanation of PROMIS scores provided by this study may help new users of the PROMIS understand the instrument, feel empowered to incorporate it into their practices, and use it as a tool for counseling patients about their scores.
Terrain classification for terrain parameter estimation based on a dynamic testing system (2015)

Purpose – This paper aims to gain the real-time terrain parameters of the battlefield for the evaluation of military vehicle trafficability. In military missions, improvements in vehicle mobility have the potential to greatly increase the military operational capacity, in which vehicle trafficability plays a significant role. Design/methodology/approach – In this framework, an online terrain parameter estimation method based on the Gauss-Newton algorithm is proposed to estimate the primary terrain mechanical parameters. Good estimation results are indicated, unless the initial values involved are properly selected. Correspondingly, a method of terrain classification is then presented to contribute to the selection of the initial values. This method uses the wavelet packet transform technique for feature extraction and adopts the support vector machine algorithm for terrain classification. Once the terrain type is identified, advices can be given on the initial value selection referring to the empirical terrain parameters. Findings – On the basis of a dynamic testing system suitable for real military vehicles, the proposed algorithms are validated. High estimation accuracy of the terrain parameters is indicated on sandy loam, and good classification performance is demonstrated on four tested terrains. Originality/value – The presented algorithm outperforms the existing methods, which not only realizes the online terrain parameter estimation but also develops the estimation accuracy. Moreover, its effectiveness is confirmed by real vehicle tests in practice.
PSR Enhancement Through Super Gain Boosting and Differential Feed-Forward Noise Cancellation in a 65-nm CMOS LDO Regulator (2013)

This paper presents a 65-nm CMOS low-dropout (LDO) regulator employing a super gain amplifier (SGA) and differential feed-forward noise cancellation to maximize the power supply rejection (PSR). The SGA in the error amplifier is augmented by a positive feedback current mirror, and this SGA boosts the loop gain through local negative feedback. With 1.2 V supply voltage, the LDO regulator has a 200 mV drop-out voltage and the ability to handle a maximum 25 mA load current. The measurement results show a -47 dB PSR ratio of up to 10 MHz and dc load regulation under 1 mV for full load current change.
Sgtα: a novel independent regulator of steroid hormone receptors (567.8) (2014)

Steroid hormone receptors (SHRs) are essential for the regulation of developmental, reproductive, and physiological homeostasis in eukaryotes. SHRs belong to the nuclear receptor superfamily, and comprise the androgen (AR), glucocorticoid (GR), progesterone (PR), mineralocorticoid (MR), and estrogen receptors (ER). Understanding the regulation of SHRs is critical for the development of novel therapeutic strategies for SHR‐mediated diseases. Heat shock protein (Hsp) 90/70 kDa assembly is essential for the dynamic chaperone complex that directs SHRs folding. A recently identified cochaperone, human small glutamine‐rich TPR‐containing protein alpha (SGTα), has been shown to negatively regulate AR by retaining AR in the cytoplasm. Using functional yeast and mammalian reporter assays, we have demonstrated that SGTα can also regulate GR and PR. Interestingly, when co‐expressed with immunophilin FKBP52, a positive regulator of the same receptors, SGTα continues to abrogate receptor activity. Another TPR‐containing protein present in yeast, CPR7, can positively regulate AR. Thus, we assessed the effects SGTα has in a yeast model system using a CPR7 deletion strain. We observed the same pattern seen with FKBP52, suggesting that the regulation by SGTα is not solely based on its TPR domain. Future studies aim to determine the role for SGTα at the transcriptional level. Grant Funding Source : Supported by the NIH/SCORE grant from the NIGMS (1SC1GM084863) and COURI
The thin blue line: a review and discussion of aseptic technique and postprocedural infections in rodents. (2000)

A basic tenet of animal welfare philosophy is that pain and distress must be minimized whenever possible without interfering with the goals of the research. Aseptic technique during surgical procedures is essential to prevent pain and distress associated with post-procedural infections. However, many investigators have found that applying the aseptic techniques used for large animal and human surgery is not always practical when performing surgery on small rodents. Furthermore, the efficacy of some of these techniques for preventing post-procedural infections has been questioned. This review examines what is known about the development of postprocedural infections in animals and humans and the methods used to prevent them. Detection of postprocedural infections in rodents can be difficult unless objective measurements of physiologic indices are made. These measurements should be used experimentally to assess the relative benefits of various methods for preventing postprocedural infections. Measures of contamination, such as quantitative bacterial cultures, also can be used; however, they do not reliably predict infection rates. Much of the dogma about decontamination of skin and hair prior to surgery is not supported by valid experimental evidence. Hair removal may not be necessary. Alcohol may in fact be a better disinfectant than is often credited. Draping should be used when it contributes to the maintenance of the sterile field, but when it does not, modification of surgical technique may provide more protection from infection than the drape does. The contribution of surgical technique to the prevention of postprocedural infections is probably equal to that of aseptic technique. Further research needs to be done to assess various aseptic techniques for use in rodent surgery.
Optimal Power Flow of Multiple Energy Carriers (2007)

This paper presents an approach for combined optimization of coupled power flows of different energy infrastructures such as electricity, gas, and district heating systems. A steady state power flow model is presented that includes conversion and transmission of an arbitrary number of energy carriers. The couplings between the different infrastructures are explicitly taken into account based on the new concept of energy hubs. With this model, combined economic dispatch and optimal power flow problems are stated covering transmission and conversion of energy. A general optimality condition for optimal dispatch of multiple energy carriers is derived, and the approach is compared with the standard method used for electrical power systems. Finally, the developed tools are demonstrated in examples
Interaction et interactivité (2017)

L’analyse des différentes formes historiques de communication avec les ordinateurs montre que l’apparition de l’écran et de l’image interactive a ancré une relation plus manipulatoire, incarnée et dynamique. Rétrospectivement, deux principaux régimes d’interactivité sont aujourd’hui bien repérables. D’un côté, l’effectuation correspond à une modalité instrumentale et distanciée typique des hypermédias, du web et des interfaces des logiciels productifs. De l’autre, l’instanciation concerne l’immersion active à travers un avatar dans un environnement simulé 3D temps réel (jeux vidéo, métavers). Avec la mise en réseau des humains et des ordinateurs, la question de l’interaction resurgit au‐ delà de la relation humain‐machine. Une nouvelle articulation conceptuelle est proposée grâce aux notions d’ethnométhode et de technométhode pour revisiter interaction et interactivité. Il en résulte à la fois des perspectives de recherches appliquées et une bonne compréhension rétrospective des confusions théoriques restées nombreuses à ce sujet.
Chemical Modification of Sweet Potato β-amylase by Mal-mPEG to Improve Its Enzymatic Characteristics (2018)

The sweet potato β-amylase (SPA) was modified by 6 types of methoxy polyethylene glycol to enhance its specific activity and thermal stability. The aims of the study were to select the optimum modifier, optimize the modification parameters, and further investigate the characterization of the modified SPA. The results showed that methoxy polyethylene glycol maleimide (molecular weight 5000, Mal-mPEG5000) was the optimum modifier of SPA; Under the optimal modification conditions, the specific activity of Mal-mPEG5000-SPA was 24.06% higher than that of the untreated SPA. Mal-mPEG5000-SPA was monomeric with a molecular weight of about 67 kDa by SDS-PAGE. The characteristics of Mal-mPEG5000-SPA were significantly improved. The K<sub>m</sub> value, V<sub>max</sub> and <i>Ea</i> in Mal-mPEG5000-SPA for sweet potato starch showed that Mal-mPEG5000-SPA had greater affinity for sweet potato starch and higher speed of hydrolysis than SPA. There was no significant difference of the metal ions' effect on Mal-mPEG5000-SPA and SPA.
Neanderthal and Denisova tooth protein variants in present-day humans (2017)

Environment parameters, diet and genetic factors interact to shape tooth morphostructure. In the human lineage, archaic and modern hominins show differences in dental traits, including enamel thickness, but variability also exists among living populations. Several polymorphisms, in particular in the non-collagenous extracellular matrix proteins of the tooth hard tissues, like enamelin, are involved in dental structure variation and defects and may be associated with dental disorders or susceptibility to caries. To gain insights into the relationships between tooth protein polymorphisms and dental structural morphology and defects, we searched for non-synonymous polymorphisms in tooth proteins from Neanderthal and Denisova hominins. The objective was to identify archaic-specific missense variants that may explain the dental morphostructural variability between extinct and modern humans, and to explore their putative impact on present-day dental phenotypes. Thirteen non-collagenous extracellular matrix proteins specific to hard dental tissues have been selected, searched in the publicly available sequence databases of Neanderthal and Denisova individuals and compared with modern human genome data. A total of 16 non-synonymous polymorphisms were identified in 6 proteins (ameloblastin, amelotin, cementum protein 1, dentin matrix acidic phosphoprotein 1, enamelin and matrix Gla protein). Most of them are encoded by dentin and enamel genes located on chromosome 4, previously reported to show signs of archaic introgression within Africa. Among the variants shared with modern humans, two are ancestral (common with apes) and one is the derived enamelin major variant, T648I (rs7671281), associated with a thinner enamel and specific to the Homo lineage. All the others are specific to Neanderthals and Denisova, and are found at a very low frequency in modern Africans or East and South Asians, suggesting that they may be related to particular dental traits or disease susceptibility in these populations. This modern regional distribution of archaic dental polymorphisms may reflect persistence of archaic variants in some populations and may contribute in part to the geographic dental variations described in modern humans.
Freezing of Enkephalinergic Functions by Multiple Noxious Foci: A Source of Pain Sensitization? (2009)

We have concluded that in addition to the concept of a diffuse control of the transmission of nociceptive signals through the dorsal horn, there is a diffuse control of the modulation of this transmission. The "freezing" of Met-enkephalinergic functions represents a potential source of central sensitization in the spinal cord, notably in clinical situations involving multiple painful foci, e.g. cancer with metastases, poly-traumatism or rheumatoid arthritis.
Spheres in an Euclidean space (2007)

Let M be an n-dimensional orientable compact hypersurface in an (n + 1)-dimensional Euclidean space R n+1 , n ≥ 2. If the gradient ∇α of the mean curvature α and the scalar curvature S of the hypersurface M satisfy the inequality Sk0 ≤ n(n − 1)k0α 2 − (n − 1) �∇ α� 2 where k0 is the infimum of the sectional curvatures of the hypersurface, then it is shown that α is a constant and M is the sphere in S n (α).
Neue Strategien in der Prävention der aktinischen Keratose: Eine kritische Literaturanalyse (2016)

Aktinische Keratose (AK) - epidermale dysplastische Läsionen nach chronischer Exposition gegenüber Sonneneinstrahlung - ist bei Personen mit hellerer Haut sehr verbreitet; die chronische Langzeit-UV-Exposition ist hierbei der Hauptrisikofaktor. Angesichts der Alterung der Bevölkerung ist zu erwarten, dass die Prävalenz der AK weiter steigen wird. AK kann zu nicht-melanomatösem Hautkrebs (NMSC) progredieren und stellt ein relevantes Problem der öffentlichen Gesundheit dar. Sechs führende Dermatologen aus Deutschland mit Spezialisierung auf AK und NMSC kamen zusammen, um über das Wesen der Erkrankung sowie die Präventions- und Behandlungsstrategien zu diskutieren, die dem Dermatologen heute zur Verfügung stehen. Während kosmetische Sonnenschutzmittel einen wesentlichen Bestandteil der Sonnenschutzstrategien darstellen, sind sie nicht ausreichend, wenn bereits Schädigung eingetreten ist. Neu entwickelte Produkte aus der Kategorie der Medizinprodukte bieten auch DNA-reparierende Eigenschaften zusätzlich zum UV-Schutz mit hohem Lichtschutzfaktor. Für die adjuvante Behandlung der AK in verschiedenen Risikostufen wurde ein Algorithmus entwickelt. Für Patienten mit niedrigem bis mittlerem Risiko wird reiner Sonnenschutz empfohlen. Für Patientengruppen mit hohem bis sehr hohem Risiko wird die ganzjährige Anwendung von Medizinprodukten empfohlen, die sehr hohen Lichtschutz mit Korrektur von Lichtschäden (durch DNA-Reparaturenzyme) kombinieren.
Δ40 Isoform of p53 Controls β-Cell Proliferation and Glucose Homeostasis in Mice (2011)

These data indicate a significant and novel role for Δ40p53 in β-cell proliferation with implications for the development of age-dependent diabetes.
Le récepteur plaquettaire de l'ADP nouvellement identifié : P2Y12 (2002)

La plaquette possede deux recepteurs de l'ADP, P2Y1 et P2Y12 appartenant a la famille des recepteurs couples aux G proteines. Ce n'est qu'en 2001 que P2Y12 a ete clone ce qui a permis de mieux connaitre les interactions des plaquettes avec l'ADP. Le gene codant pour P2Y12 est situe sur le chromosome 3. La distribution cellulaire du recepteur etudiee par Northern blot et hybridation in situ a montre sa presence dans la lignee megacaryocyto-plaquettaire et aussi au niveau du cerveau. Ce nouveau gene identifie presente peu d'homologie avec le gene codant pour P2Y1 (19 %) mais beaucoup plus avec le recepteur UDP-glucose (44 %). Le recepteur est compose de 342 acides amines. La sequence est fortement conservee entre l'homme et la souris. L'organisation genomique est similaire pour les deux especes : le cadre de lecture est code par 1 seul exon, la partie 5' non traduite contient au moins deux introns dont un se situe juste en amont du codon d'initiation. Alors que le changement de forme et l'initiation de l'agregation sont sous la dependance de P2Y1, P2Y12 est implique dans la stabilisation des agregats. Les voies de signalisation associees a P2Y12 incluent une inhibition de l'adenylate cyclase par la voie de Gialpha2 et l'activation des PI-3 kinases impliquees dans l'irreversibilite de l'agregation. P2Y12 est reconnu de maniere formelle comme etant la cible des traitements anti-agregants de la classedes thienopyridines. La seconde categorie d'agents anti-agregant actuellement developpee contre ce recepteur correspond a des analogues de l'ATP. De nouveaux anti-agregants diriges contre cette cible seront produits dans l'avenir. Le fait que ces medicaments puissent etre utilises dans des situations aigues et chroniques de risque thrombotiques avec une bonne efficacite constitue un grand progres.
Comparison between CL-316243- and CGP-12177A-Induced Relaxations in Isolated Canine Ureter (2003)

We compared the effects of CL-316243, a selective beta(3)-adrenoceptor agonist, and CGP-12177A, a nonconventional partial beta-adrenoceptor agonist, on the KCl-induced contraction in the isolated canine ureter. CL-316243 concentration dependently relaxed the ureteral contraction, the pD(2) value being 7.75 +/- 0.11. This relaxation was competitively antagonized by the selective beta(3)-adrenoceptor antagonist SR58894A and by the nonselective beta-adrenoceptor antagonist bupranolol, their pA(2) values being 7.08 +/- 0.08 and 6.43 +/- 0.09, respectively. CGP-12177A concentration dependently reduced the KCl-induced contraction, the pD(2) value being 6.30 +/- 0.25. Even at 1 x 10(-5) mol/l, CGP-20712A (a selective beta(1)- adrenoceptor antagonist) did not shift the concentration-response curves for CL-316243 or CGP-12177A. SR58894A did not induce a parallel rightward shift in the concentration-response curve for CGP-12177A, but bupranolol did produce such a shift, pA(2) and slope values in the Schild plot being 7.15 +/- 0.77 and 0.60 +/- 0.15, respectively. Hence, the competition characteristics for SR58894A and bupranolol differed between the CL- 316243-induced and CGP-12177A-induced relaxations. Our results suggest that CGP-12177A produces ureteral relaxation in the dog via an atypical beta-adrenoceptor (possibly, an atypical site/state of the beta(3)-adrenoceptor) as well as via the typical beta(3)-adrenoceptor.
Relevance of the REPUSIL process for the production of LMA thulium-doped fibers (2016)

We report on a triple-clad LMA thulium-doped fiber laser with 18μm core diameter manufactured for the first time by REPUSIL process. The fiber provides a slope efficiency of 50.4 % at 0 °C with an excellent beam quality.
NMOS and CMOS polysilicon drive circuits for liquid crystal displays (1994)

A number of circuits that form the basic elements needed for integration of the drive circuits for active matrix LC displays have been investigated. The circuits have been fabricated using a low temperature polysilicon process and measurements have been made of the circuit performance. NMOS and CMOS circuits have been compared and while ratioed NMOS circuits have a poor performance in terms of speed and power, ratioless NMOS and CMOS circuit can both provide high-speed low-power operation.
Bridging the Visible: The Modulation of the Absorption by More than 450 nm (2010)

The coexistence of 18 isomers, identified by NMR spectroscopy and gathered into six states with very different absorption properties, is observed upon irradiation with selective wavelengths of a triphotochromic system joining two naphthopyran entities through a dithienylethene bridge. The sequential electronic coupling of photochromic groups resulted in an absorption behavior reaching far into NIR.
Uniform and Partially Uniform Redistribution Rules (2007)

This short paper introduces two new fusion rules for combining quantitative basic belief assignments. These rules although very simple have not been proposed in literature so far and could serve as useful alternatives because of their low computation cost with respect to the recent advanced Proportional Conflict Redistribution rules developed in the DSmT framework.
Corticosteroid, Platelet-Rich Plasma, and Ozone Injections for Sinus Tarsi Syndrome (2022)

Ozone, CLA, or PRP injections could provide clinically significant functional improvement for at least 6 months in patients with sinus tarsi syndrome.
Performance of delinquent and nondelinquent males on planning, attention, simultaneous, and successive cognitive processing tasks (1992)

This study compared the performance of 30 White adolescent males (M age = 15 years, 8 months; SD = 7 months) and 30 incarcerated White male delinquents (M age = 15 years, 6 months, SD = 8 months) on measures of planning, attention, simultaneous, and successive cognitive processes. Normal and delinquent samples did not differ on measures of planning, simultaneous, or successive processes, but did differ significantly in selective attention. The results help clarify previous equivocal findings of attention and planning deficiencies in delinquents and suggest that A. R. Luria's model of functioning may provide a useful perspective for conceptualization of this group's cognitive competence.
Forward Error Protection for low-delay packet video (2010)

We study different forward error correction (FEC) codes for packet video streaming over erasure channels with strict delay constraints. Our study includes traditional maximum distance separable (MDS) codes and streaming burst erasure codes with optimal delay performance. We develop a continuous-times model to calculate burst error correction capabilities of these codes with a delay constraint. Our analysis also incorporates Systematic Lossy Error Protection (SLEP) that achieves stronger error protection in exchange for a slight drop in video quality when error correction is needed. We provide simulation results for transmitting H.264/AVC encoded video over a bursty packet erasure channel and show that the combination of streaming erasure codes and SLEP greatly outperforms conventional MDS FEC for video streaming with a tight delay constraint.