gebhart/patrepeval huggingface dataset:
Inhibitory effects of ambient levels of solar UV‐A and UV‐B radiation on growth of cv. New Red Fire lettuce (1998)

The influence of solar UV‐A and UV‐B radiation at Beltsville, MD, USA, on growth of Lactuca sativa L. (cv. New Red Fire lettuce) was examined during early summer of 1996 and 1997. Plants were grown from seed in plastic window boxes covered with Llumar to exclude UV‐A and UV‐B, polyester to exclude UV‐B, or tefzel (1996) or teflon (1997) to transmit UV‐A and UV‐B radiation. After 31–34 days, plants grown in the absence of solar UV‐B radiation (polyester) had 63 and 57% greater fresh weight and dry weight of tops, respectively, and 57, 72 and 47% greater dry weight of leaves, stems and roots, respectively, as compared to those grown under ambient UV‐B (tefzel or teflon). Plants protected from UV‐A radiation as well (Llumar) showed an additional 43 and 35% increase, respectively, in fresh and dry weight of tops and a 33 and 33% increase, respectively, in dry weight of leaves and stems, but no difference in root biomass over those grown under polyester. Excluding ambient UV‐B (polyester) significantly reduced the UV absorbance of leaf extracts at 270, 300 and 330 nm (presumptive flavonoids) and the concentration of anthocyanins at 550 nm as compared to those of leaf extracts from plants grown under ambient UV‐A and UV‐B. Additional removal of ambient UV‐A (Llumar) reduced the concentration of anthocyanins, but had no further effect on UV absorbance at 270, 300 or 330 nm. These findings provide evidence that UV‐B radiation is more important than UV‐A radiation for flavonoid induction in this red‐pigmented lettuce cultivar. Although previous workers have obtained decreases in lettuce yield under enhanced UV‐B, this is the first evidence for inhibitory effects of solar UV‐A and UV‐B radiation on lettuce growth.
Erratum: “Atomic layer deposition of high purity Ga2O3 films using liquid pentamethylcyclopentadienyl gallium and combinations of H2O and O2 plasma” [J. Vac. Sci. Technol. A 38, 022412 (2020)] (2021)

First Page
A compact solution for ion beam therapy with laser accelerated protons (2014)

The recent advancements in the field of laser-driven particle acceleration have made Laser-driven Ion Beam Therapy (L-IBT) an attractive alternative to the conventional particle therapy facilities. To bring this emerging technology to clinical application, we introduce the broad energy assorted depth dose deposition model which makes efficient use of the large energy spread and high dose-per-pulse of Laser Accelerated Protons (LAP) and is capable of delivering homogeneous doses to tumors. Furthermore, as a key component of L-IBT solution, we present a compact iso-centric gantry design with 360° rotation capability and an integrated shot-to-shot energy selection system for efficient transport of LAP with large energy spread to the patient. We show that gantry size could be reduced by a factor of 2–3 compared to conventional gantry systems by utilizing pulsed air-core magnets.
Abstract 18730: Effects of Maternal Prenatal Psychosocial Stress on Early Childhood Hemodynamic Responses: A Chinese Experience (2014)

Introduction: Prenatal psychosocial stress (PPS) manifesting, as anxiety (PA) and/or depression (PD), is common during human pregnancy. There are few studies in humans on long-term consequences of such stress on offspring, particularly for the cardiovascular system. Hypothesis: Maternal PPS in pregnancy altered the stress response of healthy full-term offspring during early childhood. Methods: 216 Chinese pregnant women (71, 72 and 73 during the first, second and third trimesters, respectively) underwent validated structured questionnaire-based PPS and serum cortisol level assessments. Offspring, were subjected to a 10-minute-video stress challenge at ages 7-9 years; resting and post-stress heart rate (rHR,sHR )and blood pressure (rBP, sBP) were measured. Results: The children of mothers who had experienced PPS, particularly anxiety, exhibited greater stress hemodynamic responses independently of child gender or pregnant trimesters (Table1 ). There were significant bivariate correlations between maternal cortisol and children’s resting and stress hemodynamic parameters (all P Multiple regression analyses were undertaken, separately for each trimester, with children’s hemodynamic responses as the dependent variable and including levels of PA and PD (absent, mild, moderate and severe), maternal cortisol and gender as independent variables. Effects of PA were more consistent (all P Conclusion: The results suggest a long-term influence of PA on the cardiovascular response to stress of their offspring, which might contribute to later development of cardiovascular disease later as has been documented for other prenatal influences.
Effects of Inorganic Salts on Tissue Permeability (1976)

Inorganic solutes are shown to alter the permeability of root and leaf tissues. Experiments with beet root tissues reveal that CaCl(2) decreases leakage of betacyanin from the tissue, that (NH(4))(2)SO(4) increases leakage, and that each salt can relieve the effects of the other. A comparison of cations and anions shows a range of effects with the various solutes. Experiments with Rumex obtusifolius L. leaf discs reveal that whereas CaCl(2) defers the development of senescence, (NH(4))(2)SO(4) hastens senescence and increases the leakage of materials out of the leaf discs. The solute effect on Rumex obtusifolius L. is prevented by gibberellin. CaCl(2) can relieve the (NH(4))(2)SO(4) effect. The results are interpreted as indicating that the inorganic solutes may serve to alter the permeability of membranes through alterations of interactions between water and macromolecules in the tissues; the interpretation is consistent with the evidence for opposite effects of Ca and NH(4), the effective concentrations being about 10(-3)m, and the reversibility of the effects of one solute by another of opposite stabilization-destabilization effect.
Cysteine in the triple-helical domain of one allelic product of the alpha 1(I) gene of type I collagen produces a lethal form of osteogenesis imperfecta. (1984)

We studied tissue and cultured skin fibroblasts from a newborn with the lethal perinatal form of osteogenesis imperfecta born to a mother with the Marfan syndrome and her unrelated husband. Dermis from the infant was thinner and fibril diameter smaller than control; dermal fibroblastic cells had dilated endoplasmic reticulum. His fibroblasts in culture synthesized two different species of pro alpha 1(I) chains in about equal quantity. One chain was normal, the other contained cysteine within the triple-helical portion of the COOH-terminal cyanogen bromide peptide alpha 1(I)CB6. Molecules which contained two copies of the mutant chain formed alpha 1(I)-dimers linked through interchain disulfide bonds. Molecules which contained either one or two mutant chains were delayed in secretion and underwent excessive lysyl hydroxylation and hydroxylysyl glycosylation of all chains in the molecule, probably as a result of delayed triple-helix formation. Molecules containing either one or two copies of the mutant chain melted at 38 degrees C instead of 41 degrees C. The most likely explanation for these findings is that a cysteine is substituted for a glycine in the triple-helical domain of the products of one of the alpha 1(I) alleles. Such a substitution would interfere with triple-helix formation and stability and thus explain 1) the decreased melting temperature, 2) the increased post-translational modification, 3) the altered rate of secretion and accumulation of intracellular material, 4) the increased intracellular degradation of newly synthesized collagen, and 5) the decreased collagen production. Since neither parental cell strain produced the same mutant chain, the findings are best explained by a new mutation in one of the alpha 1(I) genes. The role of the uncharacterized "Marfan" gene in modifying the phenotype in this patient is unclear.
Active Interrogation Using Electronic Neutron Generators for Nuclear Safeguards Applications (2008)

Active interrogation, a measurement technique which uses a radiation source to probe materials and generate unique signatures useful for characterizing those materials, is a powerful tool for assaying special nuclear material. The most commonly used technique for performing active interrogation is to use an electronic neutron generator as the probe radiation source. Exploiting the unique operating characteristics of these devices, including their monoenergetic neutron emissions and their ability to operate in pulsed modes, presents a number of options for performing prompt and delayed signature analyses using both photon and neutron sensors. A review of literature in this area shows multiple applications of the active neutron interrogation technique for performing nuclear nonproliferation measurements. Some examples include measuring the plutonium content of spent fuel, assaying plutonium residue in spent fuel hull claddings, assaying plutonium in aqueous fuel reprocessing process streams, and assaying nuclear fuel reprocessing facility waste streams to detect and quantify fissile material. This paper discusses the historical use of this technique and examines its context within the scope and challenges of next-generation nuclear fuel cycles and advanced concept nuclear fuel cycle facilities.
Microcomputer-based interactive tracking of blood cells at biomaterial surfaces (1989)

A microcomputer-based system for analyzing the motion of human platelets and leukocytes at synthetic surfaces from a sequence of video frames on tape is described. The software is designed to provide convenient interaction with an operator to reduce the burden of manual analysis. In addition, the system computes and stores the cell movement data on disk for subsequent statistical analysis. Measurement include the number and nature of cell-to-surface collisions, residence times, and distances traveled.
Synthesis and Solution Properties of Loose Polymer Brushes Having Polyimide Backbone and Methylmethacrylate Side Chains (2012)

Abstract Summary: Graft‐copolymers with polyimide backbone and PMMA side chains are synthesized by ATRP of methylmethacrylate on the polyimide macroinitiator. The obtained copolymers, macroinitiator, and cleaved side chains are investigated by 1 H NMR, SEC, static and dynamic light scattering, sedimentation, and viscosimetry in solutions. The synthesized copolymer is relatively loose polymer brushes: the average distance between grafted PMMA chains is ∼11 nm (4 repeat units of the backbone). The hydrodynamic and conformational characteristics of graft‐copolymers change on passage from ethylacetate to chloroform due to difference in the thermodynamic quality of the solvents with respect to the copolymer components. The backbone is characterized more extended conformation than individual polyimide macromolecule.
WHITE COAT HYPERTENSION IS CHARACTERIZED BY A SIGNIFICANT INCREASE IN THE 24-HOUR MEAN OF AMBULATORY PULSE PRESSURE (2004)

: Tuesday, June 15, 2004: POSTER SESSIONS: Poster Session 22: BP Measurements and Hemodynamics
The role of quality control in biotechnology: an analytical perspective (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe role of quality control in biotechnology: an analytical perspectiveR. L. Garnick, N. J. Solli, and P. A. PapaCite this: Anal. Chem. 1988, 60, 23, 2546–2557Publication Date (Print):December 1, 1988Publication History Published online1 May 2002Published inissue 1 December 1988https://doi.org/10.1021/ac00174a004RIGHTS & PERMISSIONSArticle Views1176Altmetric-Citations126LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (2 MB) Get e-Alertsclose Get e-Alerts
Intraneural Steroid Injection as a Complication in the Management of Carpal Tunnel Syndrome A Report of Three Cases (1990)

Steroid injection can provide symptomatic relief in patients with carpal tunnel syndrome (CTS). Its role should be limited to a diagnostic aid in cases in which symptoms are atypical, a temporizing agent in patients with severe symptoms either who are awaiting surgery or in whom spontaneous remission might be expected, and as a definitive treatment in patients who do not desire surgery. Injection should be performed using proper technique by physicians skilled in carpal tunnel surgery. A soluble preparation of dexamethasone is recommended. Immediate paresthesia in the median nerve distribution or exacerbation of symptoms beyond 48 hours following injection is suspect for inadvertent nerve injury; therefore, early surgical decompression is indicated.
0.1% RGN-259 (Thymosin ß4) Ophthalmic Solution Promotes Healing and Improves Comfort in Neurotrophic Keratopathy Patients in a Randomized, Placebo-Controlled, Double-Masked Phase III Clinical Trial (2022)

We determined the efficacy and safety of 0.1% RGN-259 ophthalmic solution (containing the regenerative protein thymosin ß4) in promoting the healing of persistent epithelial defects in patients with Stages 2 and 3 neurotrophic keratopathy. Complete healing occurred after 4 weeks in 6 of the 10 RGN-259-treated subjects and in 1 of the 8 placebo-treated subjects (<i>p</i> = 0.0656), indicating a strong efficacy trend. Additional efficacy was seen in the significant healing (<i>p</i> = 0.0359) with no recurrent defects observed at day 43, two weeks after cessation of treatment, while the one healed placebo-treated subject at day 28 suffered a recurrence at day 43. The Mackie classification disease stage improved in the RGN-259-treated group at Days 29, 36, and 43 (<i>p</i> = 0.0818, 0.0625, and 0.0467, respectively). Time to complete healing also showed a trend towards efficacy (<i>p</i> = 0.0829, Kaplan-Meier) with 0.1% RGN-259. RGN-259-treated subjects had significant improvements at multiple time points in ocular discomfort, foreign body sensation, and dryness which were not seen in the placebo group. No significant adverse effects were observed. In summary, the use of 0.1% RGN-259 promotes rapid healing of epithelial defects in neurotrophic keratopathy, improves ocular comfort, and is safe for treating this challenging population of patients.
BASELINE LABORATORY PARAMETER MODIFICATIONS ARE ASSOCIATED TO THE TRAINING RATE IN AMATEUR AND ELITE ATHLETES (2012)

Objective: The goal was to observe the physiological adaptation to different levels of physical activity vs sedentary subjects. Design: We have evaluated the effect of different training rate on the modification of the basal levels of hormonal, biochemical and haematological parameters in elite and amateur men and women performing sport activity as well as on sedentary controls. Partecipants: One hundred fifty-three subjects were enrolled in this study and divided In three categories according to the level of weekly sport training and activity. Blood Samples were obtained in rest condition for all the subjects. Results: Data obtained show that some haematochemical and endocrine parameters seems to be persistently modified and that exercise-induced changes depend on gender and on the rate of training. In particular, modification of leukocyte population percentages and reduction of glucose levels characterises both woman and men athletes. An increase of creatinkinase (CK),due to skeletal muscle hypertrophy was observed in highly trained men and women. In the group of amateur women, the CK increase was accompanied by an increase in aspartate-amino-transferase (AST) and alanine-amino-transferase (ALT). Gender and training rate specific endocrine adaptation (increase of thyroid-stimulating-hormone, estradiol and testosterone for men and decrease of cortisol and free-thyroxine for woman) profile was also identified. Conclusion: All together these data strongly suggest that the screening of blood parameters in athletes may be useful to establish a baseline to monitor the physiological/metabolic challenge arising from training
[Microcystic adenoma of the pancreas]. (1995)

Microcyst adenomas of the pancreas are rare tumours with characteristic cysts lining the cubic and cylindric epithelia with a clear cytoplasm rich in glycogen. Unlike, mucinous cyst adenomas, there is no tendency toward malignancy. We report a case in a 58-year-old woman and emphasize the importance of precise pre- or per-operative diagnosis in order to avoid excessive exeresis for benign tumour. Certain authors propose abstention and follow up.
Beta-blockade in the ischemic reperfused working rabbit heart: dissociation of beta-adrenergic blocking and protective effects. (1990)

The cardioprotective effects of the beta-blocking drugs (dl-nebivolol, d-nebivolol, propranolol, atenolol, dilevalol and pindolol) were tested in the isolated working rabbit heart. The effects of l-nebivolol, having little beta-adrenoceptor blocking activity, were also studied. The hearts were subjected to 25 min ischemia, followed by 30 min of reperfusion. In solvent-treated hearts, ischemia resulted in a considerable loss of function. The mean functional recovery of one of the most sensitive parameters, i.e. aortic flow, was only 6%. Pretreatment either with dl-nebivolol, d-nebivolol, l-nebivolol or propranol significantly improved cardiodynamic function. Recovery after pretreatment with atenolol, dilevalol and pindolol (less than 10 mg/l) was not significantly improved when compared to solvent-treated hearts. The results suggest that the protective effects of some beta-blockers are most probably not related to beta-adrenoceptor blocking activity.
Molecular cloning, expression and chromosome location of the human pelota gene PELO (2000)

The pelota gene of Drosophila melanogaster encodes a protein that was found to be included in cell cycle regulation. Mutations were found to result in spermatogenic arrest, female sterility and disturbances in the patterning of the eye. Here we describe the cloning of the human pelota cDNA (PELO) that encodes a 385-amino-acid protein. Southern blot and fluorescence in situ hybridization analyses revealed that PELO is present as a single copy gene in the human genome and is localized on chromosome 5q11.2. Northern blot analysis revealed the presence of a 1.6-kb transcript in all tissues studied and an additional 2.0-kb transcript in testis.
Transformer Networks for Predictive Group Elevator Control (2022)

We propose a Predictive Group Elevator Scheduler by using predictive information of passengers arrivals from a Transformer based destination predictor and a linear regression model that predicts remaining time to destinations. Through extensive empirical evaluation, we find that the savings of Average Waiting Time (AWT) could be as high as above 50% for light arrival streams and around 15% for medium arrival streams in afternoon down-peak traffic regimes. Such results can be obtained after carefully setting the Predicted Probability of Going to Elevator (PPGE) threshold, thus avoiding a majority of false predictions for people heading to the elevator, while achieving as high as 80% of true predictive elevator landings as early as after having seen only 60% of the whole trajectory of a passenger.
Die kombinierte Leber- und Pankreaskopfresektion zur Behandlung des fortgeschrittenen zentralen Gallengangskarzinoms (2002)

Um die Resektionsrate bei der Operation fortgeschrittener Stadien des zentralen Gallengangskarzinoms zu erhöhen, wurde ein Konzept entwickelt, das neben der rechtsseitigen Trisegmentektomie die Resektion der extrahepatischen Gallenwege, die regionale Lymphadenektomie zusammen mit der Pankreaskopfresektion vorsieht und damit sowohl die Anatomie der Gallenwege als auch das Wachstumsverhalten dieser Tumoren berücksichtigt. Das eigene Krankengut umfasst insgesamt 6 Patienten (4 Bismuth Typ III, 2 Bismuth Typ IV). Bei 5 der drei Männer und drei Frauen gelang eine R0-Resektion, wobei in zwei Fällen die Pfortader und einmal die A. hepatica mitreseziert werden mussten. Die drei Patienten, bei denen präoperativ eine Gallengangsableitung durchgeführt worden war, entwickelten nach der Operation septische Komplikationen. Neben der chirurgischen Versorgung einer Antikoagulantienblutung aus der Pankreas-Resektionsfläche musste ein rechtsseitiger Pleuraerguss bei 4 Patienten drainiert werden. Wenn auch keine Spitalsletalität zu verzeichnen war, so hat doch nur eine Patientin längerfristig rezidivfrei überlebt. Aus dieser kleinen Serie würden wir schließen wollen, dass dieses doch recht aufwändige Konzept wohl chirurgisch machbar ist, aber ohne effiziente Zusatzmaßnahmen das Überleben von Patienten mit einem fortgeschrittenen Gallengangskarzinom nur in Einzelfällen verlängern dürfte.
Binary star orbits from speckle interferometry. 5: A combined speckle/spectroscopic study of the O star binary 15 Monocerotis (1993)

We report on the discovery of a speckle binary companion to the O7 V (f) star 15 Monocerotis. A study of published radial velocities in conjunction with new measurements from Kitt Peak National Observatory (KPNO) and IUE suggests that the star is also a spectroscopic binary with a period of 25 years and a large eccentricity. Thus, 15 Mon is the first O star to bridge the gap between the spectroscopic and visual separation regimes. We have used the star's membership in the cluster NGC 2264 together with the cluster distance to derive masses of 34 and 19 solar mass for the primary and secondary, respectively. Several of the He I line profiles display a broad shallow component which we associate with the secondary, and we estimate the secondary's classification to be O9.5 Vn. The new orbit leads to several important predictions that can be tested over the next few years.