gebhart/patrepeval huggingface dataset:
Percutaneous Implantation of the Left Ventricular Partitioning Device for Chronic Heart Failure: A Pilot Study with 1-Year Follow-Up (2010)

Our data indicate that VPD implantation is safe and feasible, and that VPD implantation improves LV haemodynamics and functional capacity in the 12 months following the procedure.
A Liposomal Contrast Agent Preliminary Communication (1988)

Iopamidol-carrying liposomes were studied as potential hepatosplenographic contrast agents. Large unilamellar vesicles (0.3-1 mu) prepared from phosphatidylcholine:Dipalmotylphosphatidic acid (PC:DPPA) 9:1 and 300 MgI/mL iopamidol solution showed favorable entrapment measured as mg entrapped iodine/mg lipids (I/L). The effect of extrusion through polycarbonate membranes on liposome characteristics and in vivo distribution was investigated. Extrusion above the transition temperature of lipids reduced the average size and size distribution and increased the I/L ratio. Distribution studies of extruded and nonextruded liposomes in rats demonstrated different behavior of the preparations; extruded liposomes showed higher spleen uptake than did unextruded, while liver uptake was comparable; lung entrapment, observed with unextruded particles, was almost eliminated with extruded liposomes. Preliminary imaging studies in rats were carried out at a dose of 250 mgI/kg; typical computed tomography (CT) scans of the liver demonstrated contrast enhancement of greater than or equal to 60 HU from 90' up to 240' after injection.
The Smart Room: a 100 Mb/s integrated optical access point transceiver for indoor visible light communication (2011)

Recent developments in visible light communication (VLC) technology have solidified utilizing light-emitting diodes (LEDs) for not only illumination, but also optical wireless communication. This paper presents a novel optical access point transceiver that features addressable arrays of LEDs and photodetectors. The transmitter array enables combined illumination control and serial data transmission for an array of 16 LEDs producing an aggregate data rate of 100 Mb/s. The receiver consists of a 16-element array of broadband receiver channels. Designed in a 0.5 &mu;m CMOS process to enable miniaturization and VLC system integration, the transceiver is capable of processing multiple user requests.
Prémios, distinções e outras competições (2014)

Este artigo reflete criticamente sobre a problemática da excelência no contexto do ensino secundário português.
Full-Color Fluorescent Display Devices Using a Near-UV Light-Emitting Diode (1996)

Full-color fluorescent display devices are demonstrated using a near-UV (n-UV) light-emitting diode (LED) and various fluorescent films. ZnS:Ag (blue), ZnS:Cu,Al (green) and ZnCdS:Ag (red) powdered fluors and mixtures of them are dispersed in poly-vinyl-alcohol aqueous solutions, and fluorescent films are prepared by spin coating the suspensions to glass slides. The n-UV light emitted from a blue LED with a high injection current is irradiated onto the films, and the three primary colors and white color are easily obtained.
Pulse and Temperature Control of Thermal Ink Jet Printheads Without a Heater Passivation Layer (2008)

One of the ways to improve the heating efficiency of a heater is to eliminate the passivation layer of the heater by using TaSiO for the heater material, whereby the heater surface becomes thermally oxidized. Rapid boiling of water occurs at around 300&#xB0;C; therefore, it is necessary for the fabrication condition of the oxidation layer to correspond to a temperature higher than the boiling temperature. In a pulse drive during printing, it is also necessary to keep the heat at a temperature lower than that of thermal oxidization to prevent deterioration. As a result of observing the generation of bubbles and measuring the heater temperature, it was confirmed that within the range of heating velocity in this experiment, boiling starts at around 300&#xB0;C, and it was also possible to understand pulse control in thermal ink jet printheads to maintain the heater at an appropriate temperature.
X-Ray Diffraction data from Recombinant sperm whale myoglobin, source of 4PNJ structure (2017)

Single pulse (SASE) Free Electron Laser data collected from unexposed P6 sperm whale myoglobin crystals mounted in grids
Polymeric Foam by Photoinitiated Polymerization of Trimethylolpropanetriacrylate: Initiator and Solvent Effects (1995)

A comprehensive examination of the preparation of polymeric foam via the photopolymerization of trimethylolpropanetriacrylate, TMPTA, was undertaken. Foam properties such as uniformity, shrinkage, density, microstructure, physical integrity, and machinability were measured as a function of initiator, solvent, and processing conditions. The photopolymerization rate of TMPTA in poly(oxyethylene[4]) lauryl ether, or Brij 30, and glycol ethers is enhanced using active photoinitiators such as benzoinethylether and 2,2-dimethoxy-2-phenylacetophenone. The properties of the TMPTA foams were identical for all photoinitiators examined. The properties of the TMPTA foams were dramatically changed when a co-solvent was employed. The co-solvents were triethyleneglycol dimethyl ether and triethyleneglycol monomethyl ether. The use of co-solvents leads to greater shrinkage and a higher than expected foam density. Unlike foams prepared in Brij 30, foams prepared using glycol ethers possess good physical properties and can be machined into cylinders with a smooth surface finish.
A method of improving angle precision of conical scan LFMCW radar (2008)

In conical scan LFMCW radar, the precision of angle measurement is limited when traditional processing method is used. And in order to use this conical scan LFMCW signal in closed-loop tracking radar, one must improve the angle precision. According to analyzing the causes of angle measurement error, a method of improving the angle measurement precision is presented. Simulation results are given to verify the validity of this method.
High power and high temperature operation of 1.5 mu m wavelength strained-layer InGaAs/InGaAsP SIPBH lasers (2002)

It is demonstrated that high performance lasers can be obtained not only with compressively strained quantum wells (QWs) but also with tensile strained QWs. In addition to low threshold current (density) and high power operation, the tensile strained multiple quantum well semi-insulating planar buried heterostructure (MQW SIPBH) lasers show excellent high temperature operation (up to 140 degrees C). Compressively strained MQW SIPBH lasers are found to operate CW at record low threshold current values (0.8 mA) and record high output power (325 mW). It is concluded that both the band structure modifications induced by the strain and the quantum confinement. as well as the effective current confinement by means of semi-insulating InP, result in very high performance strained-layer MQW-SIPBH lasers.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Cavitation inception and damage effects in liquid mercury exposed to a high-energy pulsed proton beam. (2011)

The Oak Ridge National Laboratory Spallation Neutron Source (SNS) employs a high-energy proton beam incident on a liquid mercury target to generate short bursts of neutrons. Concomitant with neutron production is the rapid heating of the mercury, resulting in the formation of acoustic shock waves and the nucleation of cavitation bubbles. The subsequent collapse of these bubbles may result in the premature erosion of the target’s steel walls. We report on a multi-pronged effort to both understand and address the problem by (1) inhibiting cavitation inception using bubble injection, (2) analyze cavitation and cavitation cloud dynamics using passive noise diagnostics, and (3) mitigating vessel wall damage using surface modification techniques. [Work supported by the ORNL Spallation Neutron Source, which is managed by UT-Battelle, LLC, under Contract No. DE-AC05-00OR22725 for the U.S. Department of Energy.]
Development of textile-reinforced carbon fibre aluminium composites manufactured with gas pressure infiltration methods (2009)

Purpose: The aim of his paper is to show potential of textile-reinforced carbon fibre aluminium composite with advantage of the lightweight construction of structural components subjected to thermo-mechanical stress. Design/methodology/approach: The manufacture of specimens of the carbon fibre-reinforced aluminium was realised with the aid of an advanced differential gas pressure infiltration technique, which was developed at
Magnetostrictive Ultrasonic Delay Lines for a PCM Communication System (1960)

A servo-operated delay-line pad and a temperature-compensated delay-line memory, both magnetostrictively driven at 1.5 mc, have been used in an experimental PCM communication system.1 The delay-line pad automatically compensates for external delay changes as small as plus or minus 8 mμsec at a rate of 75 mμsec second. The delay-line memory stores 192 bits which are available serially with an access time of 125 μsec. Both applications use the same basic delay lines which consist of a length of 0.003-inch diameter supermendur wire, two tiny solenoids, and a supporting structure.
PHP (2001)

Php stands for php hypertext preprocessor (A recursive abbreviation typical of Unix-world shenanigans). PHP is a script programming language for HTML pages. The code embedded in an HTML file is executed by the server. (The Active Server Pages of Microsoft also follow this plan.)
Monoclonal antibodies to streptococcal group A carbohydrate. I. A dominant idiotypic determinant is located on Vk. (1982)

In an effort to better define the antibody repertoire to streptococcal group A carbohydrate (GAC), somatic cell hybrids were prepared from A/J mice immunized with streptococcal vaccine. Most antibodies were IgG3K and IgMK, while 2 of 26 antibodies were lambda type. Each of the IgG3 antibodies had a distinct isoelectric point consistent with previous estimates of clonal repertoires of approximately 200. IEF analysis of the L chains, however, showed that about half of the antibodies produce a common L chain, called VK1GAC, previously identified in A/J anti-GAC serum antibodies. Additional support for the structural similarity of these L chains was gained by developing an idiotype antiserum to VK1GAC. All proteins with the common L chain spectrotype react strongly with anti-VK1GAC. Thus, it appears that anti-GAC antibodies are composed of H chains bearing a few VH regions pairing with a few L chains.
Regulation of luminescence by cyclic AMP in cya-like and crp-like mutants of Vibrio fischeri (1989)

Mutants of Vibrio fischeri MJ-1 (wild type) apparently deficient in adenylate cyclase (cya-like) or cyclic AMP receptor protein (crp-like) were isolated and characterized. Compared with MJ-1, the mutants produced low levels of luminescence and luciferase. Addition of cyclic AMP restored wild-type levels of luminescence and luciferase in the cya-like mutant but not in the crp-like mutant. The results are consistent with the hypothesis that in V. fischeri cyclic AMP and cyclic AMP receptor protein are required for induction of the luminescence system.
Transient benign osteopetrosis in a calf persistently infected with bovine virus diarrhoea virus (2005)

A two-day-old Simmental calf was admitted suffering from a fracture of the right femur. The radiographs showed striking changes in all bones, evident as alter-noting zones of dense and less dense tissue (bone-in-bone) in the right femur and striped densities in the vertebral bodies. A stainless steel plate was used to repair the fracture, which healed well. The calf developed normally but was diagnosed as persistently infected with bovine virus diarrhoea (BVD) virus. It was kept in isolation and examined physically and radiographically during the following 13 months. The radiographic changes diminished during the first three months and at 13 months were barely visible. The animal was euthanatized, and immunohistochemistry revealed BVD virus antigen in numerous tissues. The radiographic abnormalities seen in this case are similar to those of the transient form of osteopetrosis in humans. Osteopetrosis in humans is currently thought to have a genetical cause, whereas it appears to be associated with viral disease in animals.
BREWSTER WINDOW AND WINDOWLESS RESONANT SPECTROPHONES FOR INTRACAVITY OPERATION - eScholarship (2012)

LBL-l0877 Preprint Submitted to Applied Physics BREWSTER WINDOW AND WINDOWLESS RESONANT SPECTROPHONES FOR INTRACAVITY OPERATION Robert Gerlach and Nabil M. Amer JUL April 1980 TWO-WEEK LOAN COpy This IS a Library Circulating Copy which may be borrowed for two weeks, a personal cOPYy Tech. Info, Division y Ext 6782, Prepared for the U.S. Department of Energy under Contract W-7405-ENG-48
Uncertainty evaluation of image-based tumour control probability models in radiotherapy of prostate cancer using a visual analytic tool (2018)

Functional imaging techniques provide radiobiological information that can be included into tumour control probability (TCP) models to enable individualized outcome predictions in radiotherapy. However, functional imaging and the derived radiobiological information are influenced by uncertainties, translating into variations in individual TCP predictions. In this study we applied a previously developed analytical tool to quantify dose and TCP uncertainty bands when initial cell density is estimated from MRI-based apparent diffusion coefficient maps of eleven patients. TCP uncertainty bands of 16% were observed at patient level, while dose variations bands up to 8 Gy were found at voxel level for an <i>iso</i>-TCP approach.
Polymerisation-related changes in THz transmission in SU8 and polystyrene (2006)

THz TDS was used to study the effects of polymerisation on THz transmission in SU8 and polystyrene. SU8 samples, spun onto a THz-transparent polyethelene substrate, were cross-linked to varying degrees using different UV exposure times. Variations in THz absorption and refractive index were observed as a function of the exposure times. Polystyrene samples were prepared as monodispersed powders with varying molecular weights. Variations of the THz refractive index with molecular weight were observed and analysed using the Claussius-Mosotti equation for the dielectric constant.
Efficacy of Vafidemstat in Experimental Autoimmune Encephalomyelitis Highlights the KDM1A/RCOR1/HDAC Epigenetic Axis in Multiple Sclerosis (2022)

Lysine specific demethylase 1 (LSD1; also known as KDM1A), is an epigenetic modulator that modifies the histone methylation status. KDM1A forms a part of protein complexes that regulate the expression of genes involved in the onset and progression of diseases such as cancer, central nervous system (CNS) disorders, viral infections, and others. Vafidemstat (ORY-2001) is a clinical stage inhibitor of KDM1A in development for the treatment of neurodegenerative and psychiatric diseases. However, the role of ORY-2001 targeting KDM1A in neuroinflammation remains to be explored. Here, we investigated the effect of ORY-2001 on immune-mediated and virus-induced encephalomyelitis, two experimental models of multiple sclerosis and neuronal damage. Oral administration of ORY-2001 ameliorated clinical signs, reduced lymphocyte egress and infiltration of immune cells into the spinal cord, and prevented demyelination. Interestingly, ORY-2001 was more effective and/or faster acting than a sphingosine 1-phosphate receptor antagonist in the effector phase of the disease and reduced the inflammatory gene expression signature characteristic ofEAE in the CNS of mice more potently. In addition, ORY-2001 induced gene expression changes concordant with a potential neuroprotective function in the brain and spinal cord and reduced neuronal glutamate excitotoxicity-derived damage in explants. These results pointed to ORY-2001 as a promising CNS epigenetic drug able to target neuroinflammatory and neurodegenerative diseases and provided preclinical support for the subsequent design of early-stage clinical trials.
When Energy Trading meets Blockchain in Electrical Power System: The State of the Art (2019)

With the rapid growth of renewable energy resources, the energy trading began to shift from centralized to distributed manner. Blockchain, as a distributed public ledger technology, has been widely adopted to design new energy trading schemes. However, there are many challenging issues for blockchain-based energy trading, i.e., low efficiency, high transaction cost, security &amp; privacy issues. To tackle with the above challenges, many solutions have been proposed. In this survey, the blockchain-based energy trading in electrical power system is thoroughly investigated. Firstly, the challenges in blockchain-based energy trading are identified. Then, the existing energy trading schemes are studied and classified into three categories based on their main focus: energy transaction, consensus mechanism, and system optimization. And each category is presented in detail. Although existing schemes can meet the specific energy trading requirements, there are still many unsolved problems. Finally, the discussion and future directions are given.
Essential Role of Insulin Receptor Substrate 1 (IRS-1) and IRS-2 in Adipocyte Differentiation (2001)

To investigate the role of insulin receptor substrate 1 (IRS-1) and IRS-2, the two ubiquitously expressed IRS proteins, in adipocyte differentiation, we established embryonic fibroblast cells with four different genotypes, i.e., wild-type, IRS-1 deficient (IRS-1(-/-)), IRS-2 deficient (IRS-2(-/-)), and IRS-1 IRS-2 double deficient (IRS-1(-/-) IRS-2(-/-)), from mouse embryos of the corresponding genotypes. The abilities of IRS-1(-/-) cells and IRS-2(-/-) cells to differentiate into adipocytes are approximately 60 and 15%, respectively, lower than that of wild-type cells, at day 8 after induction and, surprisingly, IRS-1(-/-) IRS-2(-/-) cells have no ability to differentiate into adipocytes. The expression of CCAAT/enhancer binding protein alpha (C/EBPalpha) and peroxisome proliferator-activated receptor gamma (PPARgamma) is severely decreased in IRS-1(-/-) IRS-2(-/-) cells at both the mRNA and the protein level, and the mRNAs of lipoprotein lipase and adipocyte fatty acid binding protein are severely decreased in IRS-1(-/-) IRS-2(-/-) cells. Phosphatidylinositol 3-kinase (PI 3-kinase) activity that increases during adipocyte differentiation is almost completely abolished in IRS-1(-/-) IRS-2(-/-) cells. Treatment of wild-type cells with a PI 3-kinase inhibitor, LY294002, markedly decreases the expression of C/EBPalpha and PPARgamma, a result which is associated with a complete block of adipocyte differentiation. Moreover, histologic analysis of IRS-1(-/-) IRS-2(-/-) double-knockout mice 8 h after birth reveals severe reduction in white adipose tissue mass. Our results suggest that IRS-1 and IRS-2 play a crucial role in the upregulation of the C/EBPalpha and PPARgamma expression and adipocyte differentiation.
The subcutaneous route to insulin dependent diabetes therapy (2001)

Discusses closed-loop and partially closed-loop control strategies for insulin delivery and measuring glucose concentration. The authors review the subcutaneous closed- and partially closed-loop strategies that have been proposed and tested in recent years for insulin-dependent diabetes therapy. Focus is on control, modeling, and information technology aspects, and future directions of research are also outlined. This survey complements earlier reviews concerning control approaches and application of computers in diabetes care.
Systematische Identifizierung und Öffnen von Engpässen im späten Sterol-Stoffwechsel der Hefe (2002)

No translation.
Gas phase chemistry of technetium and rhenium oxychlorides (2000)

The chloride and oxychloride chemistry of the group 7 elements Tc and Re was investigated in order to develop an experimental approach to a gas chemical characterisation of bohrium (Bh, element 107). In thermochromatography experiments with trace amounts of 101,104 Tc and 183,184 Re the formation of one volatile compound was observed in O 2 /HCl containing carrier gas, which was attributed to MO 3 Cl (M = Tc, Re). From the measured deposition temperatures the adsorption enthalpies on quartz surfaces ΔH ads (TcO 3 Cl) = -51 ± 3 kJ/mol and ΔH ads (ReO 3 Cl) = -62 ± 3 kJ/mol were evaluated. The sublimation enthalpies were derived using an empirical correlation between Δ H ads and ΔH subl : ΔH subl (TcO 3 Cl) = 49±10 kJ/mol and ΔH subl (ReO 3 Cl) = 67±10 kJ/mol. A fast gas chemical separation technique for highly volatile compounds of short-lived isotopes based on isothermal gas solid adsorption chromatography (OLGA-principle) was developed. With a modified OLGA device, model studies with the short-lived nuclides 106,107,108 Tc and 169,170,174,176 Re were carried out in preparation of an experimental gas chemical investigation of bohrium (Bh, element 107). Separation times of less than 3 s were achieved. A good separation of the oxychlorides of group 7 elements from chloride and oxychloride compounds of 152-155 Er, 151-154 Ho (as models for actinide elements), 98-101 Nb, 99-102 Zr (as models for light transactinide elements), 218 Po, and 214 Bi was accomplished in this chemical system.
Acoustic-Elastic Scattering Predictions and Experimental Verifications via Water Tank Experiments (2004)

Abstract : We are beginning a new series of laboratory acoustic experiments that will examine the detailed physics of acoustic-elastic scattering. These experiments will measure up-scattered acoustic waves, down-scattered elastic waves, and scattered interface waves from edges and embedded objects using a variety of is sensors. One of our goals is to verify a density-contrast hypothesis upon which the Wedge Assemblage numerical rough-interface scattering model is based and which is applicable to many sector acoustic environments. We are predicting some of these experimental results with calculations using fin finite difference (FD) codes that are designed for 2 and 3-D acoustic and 2-D elastic environments.
RET-Mediated Cell Adhesion and Migration Require Multiple Integrin Subunits (2010)

Our data are the first to show that multiple integrin subunits contribute to cell adhesion and migration downstream of RET, suggesting that coordinated signaling through these pathways is important for cell interactions with the microenvironment during tumor invasion and progression.
An innovative simulation model for the operations of a multipurpose seaport: a case study from Port of Wilmington, USA (2017)

The analysis of potential operating problems in a port facility is an enduring theoretical and practical problem. Because of the complexity of the problem, many existing methods have difficulties in providing a fast and reliable analysis of potential operating problems in a multipurpose port facility. In this study, a simulation model is developed to overcome this difficulty by analysing the operation of a multipurpose regional seaport in Delaware, USA. The model is implemented to identify the possible bottlenecks and optimise the operation of the port. The results of the simulation model are used to choose the optimal change in the significant elements (ship turnaround time, waiting time for bulk cargoes, containers, and trucks) of the terminal's operation.