gebhart/patrepeval huggingface dataset:
Nonsense Mutation at Codon 63 of the BRCA1 Gene in Japanese Breast Cancer Patients (1998)

The involvement of abnormalities of the BRCA1 gene in breast cancers in Japanese patients without any family history of this cancer was investigated by polymerase chain reaction-based single-strand conformation polymorphism analysis of the DNA sequences corresponding to the zinc finger domain (exons 2, 3 and 5) and the binding domain with Rad51 (exon 11) of the BRCA1 protein. An identical nonsense mutation at codon 63 (TTA to TAA) was found in 2 of 56 (3.5%) breast cancers from independent patients. The nucleotide change was also detected in the DNAs from non-cancerous tissues of both patients and therefore was a germline mutation. One of the patients was a member of a pedigree involving 3 ovarian cancer and 1 gastric cancer patients, while the other patient had no family history of malignancy. The same germline mutation at codon 63 was reported in four other independent Japanese pedigrees with frequent breast cancer, but not in such families in other countries. These observations suggest that the mutation commonly originated from a single Japanese ancestor. No other mutation of the BRCA1 gene was observed in the samples analyzed in this study. A low incidence of germline mutation and the absence of somatic mutation suggest that the aberration of the BRCA1 gene is involved only in a subset of Japanese breast cancers.
Microsporidia: Occurrence, Fate and Methodologies (2003)

Abstract Microsporidia Spores Water Sampling Detection Methods
Strong oxide-oxide interactions in silica-supported magnetite catalysts. 2. The core/shell nature of the interaction (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStrong oxide-oxide interactions in silica-supported magnetite catalysts. 2. The core/shell nature of the interactionCarl R. F. Lund and J. A. DumesicCite this: J. Phys. Chem. 1982, 86, 1, 130–135Publication Date (Print):January 1, 1982Publication History Published online1 May 2002Published inissue 1 January 1982https://pubs.acs.org/doi/10.1021/j100390a027https://doi.org/10.1021/j100390a027research-articleACS PublicationsRequest reuse permissionsArticle Views294Altmetric-Citations34LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Living carbocationic polymerization. XLVII. Polyisobutylene-containing block copolymers by sequential monomer addition. 5. Synthesis, characterization, and select properties of poly(p-tert-butylstyrene-b-isobutylene-b-p-tert-butylstyrene) (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLiving carbocationic polymerization. XLVII. Polyisobutylene-containing block copolymers by sequential monomer addition. 5. Synthesis, characterization, and select properties of poly(p-tert-butylstyrene-b-isobutylene-b-p-tert-butylstyrene)J. P. Kennedy, N. Meguriya, and B. KeszlerCite this: Macromolecules 1991, 24, 25, 6572–6577Publication Date (Print):December 1, 1991Publication History Published online1 May 2002Published inissue 1 December 1991https://doi.org/10.1021/ma00025a004RIGHTS & PERMISSIONSArticle Views171Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (562 KB) Get e-Alerts Get e-Alerts
To prevent neurodegeneration (2011)

Neurodegenerative diseases are characterized by progressive dysfunction and death of neurons in specific areas of the nervous system. Loss of neurons is often associated with multiple stresses such as abnormal aggregation of misfolded proteins, deficiency of protein degradation system, mitochondrial dysfunction and excessive oxidative products. HDAC6 has recently been suggested to be an integral factor that copes with these stresses. In this mini-review, we summarize our current understanding of how HDAC6 promotes inclusion formation, facilitates autophagic degradation of protein aggregates and dysfunctional mitochondria. Finally, the possibility for HDAC6 to be a potential preventional and therapeutical target of some neurodegenerative diseases is put forward.
Optimized Chemical Stability and Electrochemical Performance of LiFePO[sub 4] Composite Materials Obtained by ZnO Coating (2008)

An improved electrode performance is achieved in materials of different origin by a simple coating procedure. samples were prepared by a conventional ceramic synthesis. Mössbauer data evidenced that heating above with carbon should be avoided to limit the amount of iron phosphide impurities. The ceramic sample was compared to a commercial sample differing in particle size and porous system. ZnO precipitation of a ca. films on the particles surface of both phosphate samples resulted in a protection vs electrolyte hydrolysis product that limits iron dissolution during lithium battery operation. As a consequence, capacity retention improves significantly at different rates.
Electrical and optical response of depleting carrier in active PIN silicon waveguide (2015)

Change in refractive index and corresponding change in optical properties like propagation loss, group index and dispersion in active PIN silicon waveguide with and without photonic crystal core are investigated by changing doping concentration. This investigation sets a bound on doping density which is utilized to change effective refractive index for various applications like modulation, switching, dispersion compensation, slowing light and so on. Influences of depleting carriers on junction capacitance and reverse current behaviors are also investigated for same waveguides. This sets a benchmark for the design and selection of appropriate waveguide for various applications in silicon photonics platform.
Analysis of sparsely sampled phased array antenna for advanced Doppler radar (2014)

This paper documents the study of a sparsely sampled phased array antenna used for an avalanche radar in VDLS. The fully populated array of 144 elements (16 × 9) is analysed and some of the prominent result are tabulated in this paper findings. The thinning method is based on the previous knowledge of the iterative method compiled by the author. It is shown that with the right thinning of the antenna elements, the beampattern of the phased array antenna could be controlled to give the desired pattern to the designer.
Movement control algorithms for realization of fault-tolerant ad hoc robot networks (2004)

Autonomous and semi-autonomous mobile multirobot systems require a wireless communication network in order to communicate with each other and collaboratively accomplish a given task. A multihop communications network that is self-forming, self-healing, and self-organizing is ideally suited for such mobile robot systems that exist in unpredictable and constantly changing environments. However, since every node in a multihop (or ad hoc) network is responsible for forwarding packets to other nodes, the failure of a critical node can result in a network partition. Hence, it is ideal to have an ad hoc network configuration that can tolerate temporary failures while allowing recovery. Since movement of the robot nodes is controllable, it is possible to achieve such fault-tolerant configurations by moving a subset of robots to new locations. In this article we propose a few simple algorithms for achieving the baseline graph theoretic metric of tolerance to node failures, namely, biconnectivity. We formulate an optimization problem for the creation of a movement plan while minimizing the total distance moved by the robots. For one-dimensional networks, we show that the problem of achieving a biconnected network topology can be formulated as a linear program; the latter lends itself to an optimal polynomial time solution. For two-dimensional networks the problem is much harder, and we propose efficient heuristic approaches for achieving biconnectivity. We compare the performance of the proposed algorithms with each other with respect to the total distance moved metric using simulations.
Proactive esophageal cooling protects against thermal insults during high-power short-duration radiofrequency cardiac ablation (2022)

Proactive esophageal cooling significantly reduces temperatures and the resulting fraction of damage in the esophagus during HPSD ablation. These findings offer a mechanistic rationale explaining the high degree of safety encountered to date using proactive esophageal cooling, and further underscore the fact that temperature monitoring is inadequate to avoid thermal damage to the esophagus.
A coelectroporation method for the isolation of cryptic plasmids from Lactococcus lactis (2001)

The method facilitates the isolation of cryptic plasmids, helps in assigning functions to unknown plasmids and allows construction of food-grade lactococcal strains with new combinations of wild-type plasmids.
Probabilistic learning of salient patterns across spatially separated, uncalibrated views (2004)

We present a solution to the problem of tracking intermittent targets that can overcome long-term occlusions as well as movement between camera views. Unlike other approaches, our system does not require topological knowledge of the site or labelled training patterns during the learning period. The approach uses the statistical consistency of data obtained automatically over an extended period of time rather than explicit geometric calibration to automatically learn the salient reappearance periods for objects. This allows us to predict where objects may reappear and within how long. We demonstrate how these salient reappearance periods can be used with a model of physical appearance to track objects between spatially separate regions in single and separated views.
Electron Microscopy Characterization of Pd-Ce Interaction on α-Al2O3 Support (2008)

Extended abstract of a paper presented at Microscopy and Microanalysis 2008 in Albuquerque, New Mexico, USA, August 3 – August 7, 2008
Recovery of Campylobacter Species from Homosexual Men (1988)

Journal Article Recovery of Campylobacter Species from Homosexual Men Get access Barbara E. Laughon, Barbara E. Laughon Search for other works by this author on: Oxford Academic PubMed Google Scholar Andrew A. Vernon, Andrew A. Vernon Search for other works by this author on: Oxford Academic PubMed Google Scholar Dolph A. Druckman, Dolph A. Druckman Search for other works by this author on: Oxford Academic PubMed Google Scholar Robin Fox, Robin Fox Search for other works by this author on: Oxford Academic PubMed Google Scholar Thomas C. Quinn, Thomas C. Quinn Search for other works by this author on: Oxford Academic PubMed Google Scholar B. Frank Polk, B. Frank Polk Search for other works by this author on: Oxford Academic PubMed Google Scholar John G. Bartlett John G. Bartlett Search for other works by this author on: Oxford Academic PubMed Google Scholar The Journal of Infectious Diseases, Volume 158, Issue 2, August 1988, Pages 464–467, https://doi.org/10.1093/infdis/158.2.464 Published: 01 August 1988 Article history Received: 02 November 1987 Revision received: 03 March 1988 Published: 01 August 1988
Surface Modification and Characterization of Perovskite-Type Mixed Ionic-Electronic Conductors (2004)

Surface modification effects have been investigated for perovskite-type mixed ionic-electronic conductors. As the mixed conducting oxides show both ionic and electronic conductivity, these can be applied as oxygen permeable membranes. We have coated surfaces of the perovskite-type mixed conductors, LaSrCoFeO3 and LaSrGaFeO3, with LaSrCoO3 and investigated the effects on oxygen permeability. Enhanced oxygen permeability was achieved when the LaSrGaFeO3 membrane was surface-modified with LaSrCoO3. However, there was no effect on oxygen permeability of LaSrCoFeO3 even when the surface of which was modified. The morphological factors related with electrochemical reactions have also been discussed
Rapid, Heterogeneous Biocatalytic Hydrogenation and Deuteration in a Continuous Flow Reactor (2020)

Abstract The high selectivity of biocatalysis offers a valuable method for greener, more efficient production of enantiopure molecules. Operating immobilised enzymes in flow reactors can improve the productivity and handling of biocatalysts, and using H 2 gas to drive redox enzymes bridges the gap to more traditional metal‐catalysed hydrogenation chemistry. Herein, we describe examples of H 2 ‐driven heterogeneous biocatalysis in flow employing enzymes immobilised on a carbon nanotube column, achieving near‐quantitative conversion in &lt;5 min residence time. Cofactor recycling is carried out in‐situ using H 2 gas as a clean reductant, in a completely atom‐efficient process. The flow system is demonstrated for cofactor conversion, reductive amination and ketone reduction, and then extended to biocatalytic deuteration for the selective production of isotopically labelled chemicals.
Impact of sample size on principal component analysis ordination of an environmental data set: effects on eigenstructure (2016)

Abstract In this study, we used bootstrap simulation of a real data set to investigate the impact of sample size (N = 20, 30, 40 and 50) on the eigenvalues and eigenvectors resulting from principal component analysis (PCA). For each sample size, 100 bootstrap samples were drawn from environmental data matrix pertaining to water quality variables (p = 22) of a small data set comprising of 55 samples (stations from where water samples were collected). Because in ecology and environmental sciences the data sets are invariably small owing to high cost of collection and analysis of samples, we restricted our study to relatively small sample sizes. We focused attention on comparison of first 6 eigenvectors and first 10 eigenvalues. Data sets were compared using agglomerative cluster analysis using Ward’s method that does not require any stringent distributional assumptions.
Link Homophily in the Application Layer and its Usage in Traffic Classification (2010)

We address the following questions. Is there link homophily in the application layer traffic? If so, can it be used to accurately classify traffic in network trace data without relying on payloads or properties at the flow level? Our research shows that the answers to both of these questions are affirmative in real network trace data. Specifically, we define link homophily to be the tendency for flows with common IP hosts to have the same application (P2P, Web, etc.) compared to randomly selected flows. The presence of link homophily in trace data provides us with statistical dependencies between flows that share common IP hosts. We utilize these dependencies to classify application layer traffic without relying on payloads or properties at the flow level. In particular, we introduce a new statistical relational learning algorithm, called Neighboring Link Classifier with Relaxation Labeling (NLC+RL). Our algorithm has no training phase and does not require features to be constructed. All that it needs to start the classification process is traffic information on a small portion of the initial flows, which we refer to as seeds. In all our traces, NLC+RL achieves above 90% accuracy with less than 5% seed size; it is robust to errors in the seeds and various seed-selection biases; and it is able to accurately classify challenging traffic such as P2P with over 90% Precision and Recall.
Fast and efficient vertical handoffs in wireless overlay networks (2005)

Mobile IP is used to keep track of location information and make the data available to the mobile device anytime, anywhere. It designed to address the macromobility management problem, it does not address microlevel mobility issues such as handoff latency and packet loss. In this paper, we propose a fast and efficient handoff scheme to handle the movements of mobile nodes among a different wireless network technologies. Our scheme combines: (a) A hierarchical mobility management architecture to hide mobility of mobile nodes within the foreign domain from the home agent, (b) The use of multicast as the packet forwarding mechanism from the getaway foreign agent to the base stations, (c) The use of our proposed virtual cells in order to reduce the upward vertical handoff latency and disruption as much as possible. Our design is based on the Internet protocol (IP) and is compatible with the mobile IP standard (MIP). We also present simulation results showing that our handoff scheme is very fast and avoid packet loss.
Structure of Cooked Spaghetti of Durum and Bread Wheats (2003)

Abstract The structure of cooked spaghetti of durum and bread wheats was studied using low voltage scanning electron microscopy, and light microscopy applying different staining methods. Central, intermediate and external regions, and four zones along the external region of cooked spaghetti strands, were characterized in unprecedented detail. Changes in structure of starch granules from core to surface portrayed the successive stages in starch gelatinization, and possible starch retrogradation in the external region. Pronounced changes in shape of starch granules commenced in the intermediate region, while apparent internal changes dominated in the external region. Spaghetti of bread wheats differed from that of durum wheats by the larger size and higher extent of fusions and retrogradation of starch, and less amounts and continuity of intervening proteins. The significance of a high protein concentration for pasta production from bread wheats was emphasized. Furthermore, the relevance of a small size of the large starch granules was inferred.
Stereo vision VLSI processor based on a recursive computation algorithm (2003)

Stereo vision is a well-known method for three-dimensional instrumentation. A major issue of stereo vision is to establish reliable correspondence between images. This paper presents a high-speed corresponding matching algorithm based on recursive SAD (sum of absolute differences) computation. Since the recursive SAD computation can be performed in parallel and have regular data dependencies, the proposed algorithm is well suitable for VLSI implementation. A VLSI processor architecture based on area-time minimization is also discussed to achieve highly-parallel processing and a simple interconnection network among processing elements.
Tilted wave interferometry for testing large surfaces (2018)

Measuring large surfaces interferometrically is a straight forward established technology, as long as they are concave and spherical. The situation chnages completely if aspheres and freeforms have to be measured. The application of a Tilted Wave Interferometer opens up possibilities to measure large concave surfaces of any shape without compensation optics. For the investigation of large convex aspheres, it is necessary to make use of stitching methods. Due to the freeform capability of the Tilted Wave Interefrometer, it is possible to acquire larger subapertures compared to null interferometers. Therefore measurement and computation time are reduced.
Employing a Single-Screw Expander in an Organic Rankine Cycle with Liquid Flooded Expansion and Internal Regeneration (2017)

Positive displacement expanders are proven to be cost-effective in the low to medium power range for Organic Rankine Cycle (ORC) systems. Among the different types of volumetric expanders, the screw-type presents a favorable combination of relatively high internal volume ratio (up to 7) and isentropic efficiency (up to 80%) with respect to the optimal pressure ratio at which sub-critical ORCs operate. In particular, single-screw expanders have shown some potential due to their symmetric and balanced configuration that decreases the loads on the bearings. A comprehensive characterization of this type of machine with two working fluids, i.e., SES36 and R245fa, has been carried out in a previous work [1]. Based on the experimental work, friction losses and internal leakages were found detrimental to the expander performance. As the expander requires lubrication during operation, flooded expansion can be beneficial to reduce such losses as well as to improve the expansion process toward a quasi-isothermal behavior. A thermodynamic cycle model has been developed to evaluate the potential improvements on the thermodynamic performance of organic Rankine cycle with flooded expansion and internal regeneration. A semi-empirical model of the expander is included which accounts for the effects of internal volume ratio. The results from the cycle model have used to design an ORC test setup with an independent lubricant oil loop and internal regeneration. The new test rig will be used validate the trends obtained with the cycle model and to further characterize the single-screw expander. The working fluid employed is R1233zd(E) as a replacement for R245fa.