gebhart/patrepeval huggingface dataset:
Cross-linking of the dermo-epidermal junction of skin regenerating from keratinocyte autografts. Anchoring fibrils are a target for tissue transglutaminase. (1996)

Since transglutaminases create covalent gamma-glutamyl-epsilon-lysine cross-links between extracellular matrix proteins they are prime candidates for stabilizing tissue during wound healing. Therefore, we studied the temporo-spatial expression of transglutaminase activity in skin regenerating from cultured epithelial autografts in severely burned children by the specific incorporation of monodansylcadaverine into cryostat sections from skin biopsies obtained between 5 d to 17 mo after grafting. The dansyl label was subsequently immunolocalized in the epidermis, dermal connective tissue, and along the basement membrane. Incubation of cryosections of normal and regenerating skin with purified tissue transglutaminase confirmed the dermo-epidermal junction and the papillary dermis as targets for this enzyme and revealed that in regenerating skin transamidation of the basement membrane zone was completed only 4-5 mo after grafting. Immunoelectron microscopy revealed that three distinct regions on the central portion of anchoring fibrils were positive for monodansylcadaverine in normal skin which were negative during the initial phase of de novo formation of anchoring fibrils in regenerating skin. Biochemically, we identified collagen VII as potential substrate for tissue transglutaminase. Thus, tissue transglutaminase appears to play an important role not only in cross-linking of the papillary dermis but also of the dermo-epidermal junction in particular.
Population-Based Risk for Complications After Transthoracic Needle Lung Biopsy of a Pulmonary Nodule: An Analysis of Discharge Records (2011)

Department of Veterans Affairs and National Cancer Institute.
TU‐C‐134‐01: Nuclear Medicine Advances in Instrumentation: PET/MRI Technical Design Challenges & Innovations (2013)

PET/MR is an exciting new addition to the suite of commercially available hybrid imaging technologies. Although, there has been continued research on the integration of PET and MR since the initial demonstration of the proof‐of‐concept in the mid‐1990' s, it is only more recently that hybrid PET/MR systems have become a clinical reality. A number of different PET/MR integration designs were explored and crucial technological advancements were necessary before commercialization of clinical PET/MR systems became a reality. Learning Objectives: 1. Present the historical development of PET/MR systems 2. Overview of PET/MR image formation, artifacts, and clinical applications 3. Design considerations, challenges, and technological advancements for clinical implementation of PET/MR
The temperature and pressure dependence of viscosity and volume for two reference liquids (2015)

The new quantitative elastohydrodynamics has resulted in rapid advances in understanding concentrated contact lubrication behaviour by employing real transport properties. A key component of this revolution has been the use of reference liquids. In this paper, two liquids, a triester and a perfluoropolyether, which are under consideration as possible viscosity standards are characterised to 1 GPa for conditions relevant to tribology. Two correlations are provided for interpolation and data smoothing, and an explanation for difficulties encountered with free volume theory is offered. The perfluoropolyether is only appropriate as a reference liquid when an identical lot is available. Copyright © 2015 John Wiley & Sons, Ltd.
A Synergetic Micromechanics Model For Fiber Reinforced Composites (2011)

Composite materials show heterogeneity at different length scales. hence concurrent multiscale analysis is the only reliable method to analyze them. But unfortunately there is no concurrent multi-scale strategy that is efficient, and accurate while addressing all kinds of problems. This lack of reliability is partly because there is no micro-mechanical model which inherently keeps all relevent global information with it. This thesis tries to fill this gap. The
presented micro-mechanical model not only homogenizes the micro-structure but also keeps the global information with it. Most of the micro-mechanical models in the literature extract the Representative Volume Element (RVE) from the continuum for analysis which results in loss of information and accuracy. In the present approach also, the RVE has been extracted
from the continuum but with the major difference that all the macro/meso-scopic parameters are accounted for. Five macro/meso-scopic one dimensional parameters have been defined which completely define the effect of continuum. 11 for one dimensional stretch, _1 for torsion, __ (_ = 2, 3) for bending and _33 for uniform pressurization due to the presence
of the continuum. Further, the above macro/meso-scopic parameters are proven, by the asymptotic, theory to be constant at a cross section but vary, in general, over the length of the fiber. Hence, the analysis is valid for any location and is not restricted to any local domain.
Three major problems have been addressed:
• Homogenization and analysis of RVE without any defects
• Homogenization and analysis of RVE with fiber-matrix de-bonding
• Homogenization and analysis of RVE with radial matrix cracking.
Variational Asymptotic Method (VAM) has been used to solve the above mentioned problems
analytically. The results have been compared against standard results in the literature and
against 3D FEA.
At the end, results for “Radial deformation due to torsion” problem will be presented
which was solved “accidentally.”
OBSERVATION OF COMBINATION BANDS INVOLVING INTERMOLECULAR VIBRATIONS OF N$_2$O-N$_2$, N$_2$O-OCS AND N$_2$O-CO$_2$ COMPLEXES USING AN EXTERNAL CAVITY QUANTUM CASCADE LASER (2013)

Author Institution: Department of Physics and Astronomy, University of Calgary, 2500 University Dr., N.W., Calgary, Alberta T2N 1N4, Canada; National Research Council of Canada, Ottawa, Ontario, K1A 0R6, Canada
SALL1 expression in the human pituitary-adrenal/gonadal axis (2002)

SALL1 was originally identified on the basis of its DNA sequence homology to the region-specific homeotic gene Sal, in Drosophila melanogaster, which acts as a downstream target of hedgehog/tumor growth factor-beta-like decapentaplegic signals. The SALL1 gene has been associated with the Townes-Brocks Syndrome (TBS), a disorder characterized by multiorgan dysgenesis including renal and genital malformations. In this study, SALL1 message production was evaluated in association with the tissue localization of the protein product of SALL1, p140. SALL1 protein expression was observed in various adult and fetal tissues which elaborate reproductive endocrine hormones. The p140 was localized in specific microanatomic sites of the pituitary, adrenal cortex and the placenta. In the human pituitary, SALL1 protein expression was limited to the adenohypophysis, where it colocalized to those cells producing GH and the gonadotropins, LH and FSH. SALL1 expression was also found in most of the fetal and adult adrenal cortex in addition to the trophoblastic cells of the placenta. This pattern of expression complements prior studies demonstrating p140 in testicular fetal Leydig cells, adult Leydig and Sertoli cells, and granulosa cells of the ovary. The SALL1 protein was also shown here to be highly expressed in trophoblast tumors, which overproduce sex hormones. The expression patterns of SALL1 at multiple levels of the reproductive endocrine axis and the phenotypic effects associated with TBS suggest that SALL1 may have an important role in the interaction of the pituitary-adrenal/gonadal axis during reproduction.
Treatment of Schizoaffective Disorder and Schizophrenia With Mood Symptoms (1999)

Empirical data suggest that both groups of patients are best treated by optimizing antipsychotic treatment and that atypical antipsychotics may prove to be most effective. Adjunctive antidepressants may be useful for patients with major depression who are not acutely ill. Careful longitudinal assessment is required to ensure identification of primary mood disorders.
Effects of Halothane on the Phrenic Nerve Responses to Carbon Dioxide Mediated by Carotid Body Chemoreceptors in Vagotomized Dogs (1997)

The phrenic nerve response to an acute, severe carbon dioxide stimulus was dose dependently depressed by surgical doses of halothane. The observed responses to carbon dioxide infusion were mediated by the CBCRs because they were eliminated by CBCR denervation. These results suggest that the CBCR transduction and central transmission of the carbon dioxide signal in terms of inspiratory excitatory drive are not abolished at surgical levels of halothane anesthesia.
Comparing (stochastic-selection) ab initio multiple spawning with trajectory surface hopping for the photodynamics of cyclopropanone, fulvene, and dithiane (2021)

Ab Initio Multiple Spawning (AIMS) simulates the excited-state dynamics of molecular systems by representing nuclear wavepackets in a basis of coupled traveling Gaussian functions, called trajectory basis functions (TBFs). New TBFs are spawned when nuclear wavepackets enter regions of strong nonadiabaticity, permitting the description of non-Born-Oppenheimer processes. The spawning algorithm is simultaneously the blessing and the curse of the AIMS method: it allows for an accurate description of the transfer of nuclear amplitude between different electronic states, but it also dramatically increases the computational cost of the AIMS dynamics as all TBFs are coupled. Recently, a strategy coined stochastic-selection AIMS (SSAIMS) was devised to limit the ever-growing number of TBFs and tested on simple molecules. In this work, we use the photodynamics of three different molecules-cyclopropanone, fulvene, and 1,2-dithiane-to investigate (i) the potential of SSAIMS to reproduce reference AIMS results for challenging nonadiabatic dynamics, (ii) the compromise achieved by SSAIMS in obtaining accurate results while using the smallest average number of TBFs as possible, and (iii) the performance of SSAIMS in comparison to the mixed quantum/classical method trajectory surface hopping (TSH)-both in terms of its accuracy and computational cost. We show that SSAIMS can accurately reproduce the AIMS results for the three molecules considered at a much cheaper computational cost, often close to that of TSH. We deduce from these tests that an overlap-based criterion for the stochastic-selection process leads to the best agreement with the reference AIMS dynamics for the smallest average number of TBFs.
Benzamidine Derivatives (1949)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBenzamidine DerivativesEllis K. FieldsCite this: J. Am. Chem. Soc. 1949, 71, 4, 1495–1496Publication Date (Print):April 1, 1949Publication History Published online1 May 2002Published inissue 1 April 1949https://pubs.acs.org/doi/10.1021/ja01172a505https://doi.org/10.1021/ja01172a505research-articleACS PublicationsRequest reuse permissionsArticle Views168Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Biological nitrogen fixation by pulse crops on the semiarid Canadian Prairie (2016)

Pulses play a significant role in nitrogen cycling as they fix atmospheric N2 through symbiosis. However, it is unknown whether there are differences in the ability of biological nitrogen fixation (BNF) among pulse species and individual cultivars. Here we quantified the BNF ability of selected pulse cultivars and determined the effect on crop yield. A total of 25 species-cultivar combinations of chickpea (Cicer arietinum L.), dry bean (Phaseolus vulgaris L.), faba bean (Vicia faba L.), field pea (Pisum sativum L.), and lentil (Lens culinaris Medik.) were tested in 2008-2010. Pulses had a higher BNF in the wetter 2010 and lower in the drier 2009. In 2010, faba bean and chickpea had highest BNF at 106 kg N ha-1, followed by lentil, field pea and dry bean at 87, 69 and 12 kg N ha-1, respectively. Across years, field pea had most stable BNF ability, fixing 55 kg N ha-1 with an average seed yield of 2418 kg ha-1. There are large differences in BNF and yield among cultivars within a species and the magnitude of the difference varied with years. Large genetic variability in BNF and yield suggest the possibility that pulse cultivars with a higher N2-fixing ability and seed yield can be developed through selection of N2-fixing trait.
Cholinergic receptor activation on epithelia protects against cytokine‐induced barrier dysfunction (2015)

Acetylcholine acts on muscarinic receptors on epithelial cells to maintain epithelial barrier function under inflammatory conditions.
Multi-colour FISH in oesophageal adenocarcinoma—predictors of prognosis independent of stage and grade (2014)

Cell signal number of the ERBB2 and ZNF217 loci showed independence from tumour stage and differentiation grade. The prognostic value of multi-colour FISH-assays is applicable to EAC and is superior to single markers.
Localisation in vitro par cytométrie en image à balayage laser (CIBL) des sites d'accrochage de toxine de Bacillus thuringiensis chez les insectes (1994)

La cytométrie en image à balayage laser (CIBL) permet de localiser et de quantifier la fluorescence au niveau tissulaire. Des observations préliminaires ont été réalisées sur des sections histologiques de larves de lépidoptères afin de mettre en évidence, après immunomarquage en fluorescence, la distribution des sites d'accrochage des toxines de B. thuringiensis. Les premiers résultats montrent que, si le marquage visualisé (et quantifié) se trouve bien au niveau des microvillosités, il n'est pas continu. Il serait préférentiellement localisé dans des zones précises de l'intestin moyen de l'insecte.
Sol–gel coating of inorganic nanostructures with resorcinol–formaldehyde resin (2013)

A general sol-gel process has been developed to form a coating of resorcinol-formaldehyde (RF) resin on inorganic nanostructures of various compositions and morphologies. The RF shell can be conveniently converted into carbon through high temperature carbonization under an inert atmosphere.
Observation Modelling for Vision-Based Target Search by Unmanned Aerial Vehicles (2015)

Unmanned Aerial Vehicles (UAVs) are playing an increasing role in gathering information about objects on the ground. In particular, a key problem is to detect and classify objects from a sequence of camera images. However, existing systems typically adopt an idealised model of sensor observations, by assuming they are independent, and take the form of maximum likelihood predictions of an object's class. In contrast, real vision systems produce output that can be highly correlated and corrupted by noise. Therefore, traditional approaches can lead to inaccurate or overconfident results, which in turn lead to poor decisions about what to observe next to improve these predictions.To address these issues, we develop a Gaussian Process based observation model that characterises the correlation between classifier outputs as a function of UAV position. We then use this to fuse classifier observations from a sequence of images and to plan the UAV's movements. In both real and simulated target search scenarios, we show that this can achieve a decrease in mean squared detection error of up to 66% relative to existing state-of-the-art methods.
Mind the gap! tailoring sol–gel ceramic mesoporous coatings on labile metal–organic frameworks through kinetic control (2021)

Kinetic control allows for the synthesis of mesoporous silica shells on top of labile ZIF-8 cores without compromising MOF stability.
A Case Study on Using Data Mining for University Curricula (2012)

In former work, the authors developed a modeling system for university learning processes, which aims at evaluating and refining university curricula to reach an optimum of learning success in terms of best possible best possible grade point average (GPA). This is performed by applying an Educational Data Mining (EDM) technology to former students curricula and their degree of success (GPA) and thus, uncovering golden didactic knowledge for successful education. We shifted strategy from an "eager" strategy of holding an explicit model towards a "lazy" strategy of mining with data, which is really available, holds empirically, and is not a result of "guesses" about the students' general characteristics. In particular, we utilize the educational history of the students and vocational ambitions for student modeling.
Unexpected Specificity of Interspecies Cobamide Transfer from Geobacter spp. to Organohalide-Respiring Dehalococcoides mccartyi Strains (2012)

Dehalococcoides mccartyi strains conserve energy from reductive dechlorination reactions catalyzed by corrinoid-dependent reductive dehalogenase enzyme systems. Dehalococcoides lacks the ability for de novo corrinoid synthesis, and pure cultures require the addition of cyanocobalamin (vitamin B(12)) for growth. In contrast, Geobacter lovleyi, which dechlorinates tetrachloroethene to cis-1,2-dichloroethene (cis-DCE), and the nondechlorinating species Geobacter sulfurreducens have complete sets of cobamide biosynthesis genes and produced 12.9 ± 2.4 and 24.2 ± 5.8 ng of extracellular cobamide per liter of culture suspension, respectively, during growth with acetate and fumarate in a completely synthetic medium. G. lovleyi-D. mccartyi strain BAV1 or strain FL2 cocultures provided evidence for interspecies corrinoid transfer, and cis-DCE was dechlorinated to vinyl chloride and ethene concomitant with Dehalococcoides growth. In contrast, negligible increase in Dehalococcoides 16S rRNA gene copies and insignificant dechlorination occurred in G. sulfurreducens-D. mccartyi strain BAV1 or strain FL2 cocultures. Apparently, G. lovleyi produces a cobamide that complements Dehalococcoides' nutritional requirements, whereas G. sulfurreducens does not. Interestingly, Dehalococcoides dechlorination activity and growth could be restored in G. sulfurreducens-Dehalococcoides cocultures by adding 10 μM 5',6'-dimethylbenzimidazole. Observations made with the G. sulfurreducens-Dehalococcoides cocultures suggest that the exchange of the lower ligand generated a cobalamin, which supported Dehalococcoides activity. These findings have implications for in situ bioremediation and suggest that the corrinoid metabolism of Dehalococcoides must be understood to faithfully predict, and possibly enhance, reductive dechlorination activities.
Evidence for fluxionality in solid tetracobalt dodecacarbonyl (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEvidence for fluxionality in solid tetracobalt dodecacarbonylBrian E. Hanson and Edward C. LisicCite this: Inorg. Chem. 1986, 25, 6, 715–716Publication Date (Print):March 1, 1986Publication History Published online1 May 2002Published inissue 1 March 1986https://pubs.acs.org/doi/10.1021/ic00226a001https://doi.org/10.1021/ic00226a001research-articleACS PublicationsRequest reuse permissionsArticle Views75Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
DHIs validation for Amauligak oil field, Canadian Beaufort Sea (1989)

The giant Amauligak field is a three-way fault bounded block situated in the eastern area of the Beaufort Sea known as the growth fault sector. The Amauligak structure was triggered by a major synsedimentary fault trending northeast-southwest. Interbedded sands and shales of the Oligocene Kugmallit Sequence (Pullen delta front) form the core of the structure. A strong amplitude anomaly was recognized on older seismic data in the crestal area of the structure at the top of the Kugmallit Sequence-Pullen unconformity level. Recent (1986) exploration three-dimensional data reveal diverse DHIs including: bright spots, phase change, shadow zone and flat spot, all associated with a large gas cap. Interpretation of seismic data and interactive seismic modeling suggest that a combination of structural, stratigraphic, and hydrodynamic factors are responsible for the aspect and distribution of DHIs at the Amauligak field. Although the gas/liquid contact is seismically mappable over the field, the nature of the downdip liquid remained unknown. To overcome this ambiguity, highly deviated wells were drilled to investigate the reservoir above and below the edge of the amplitude anomaly.
Multi-template Scale-Adaptive Kernelized Correlation Filters (2015)

This paper identifies the major drawbacks of a very computationally efficient and state-of-the-art-tracker known as the Kernelized Correlation Filter (KCF) tracker. These drawbacks include an assumed fixed scale of the target in every frame, as well as, a heuristic update strategy of the filter taps to incorporate historical tracking information (i.e. simple linear combination of taps from the previous frame). In our approach, we update the scale of the tracker by maximizing over the posterior distribution of a grid of scales. As for the filter update, we prove and show that it is possible to use all previous training examples to update the filter taps very efficiently using fixed-point optimization. We validate the efficacy of our approach on two tracking datasets, VOT2014 and VOT2015.