gebhart/patrepeval huggingface dataset:
Cognitive deficits in multiple sclerosis correlate with changes in fronto-subcortical tracts (2008)

Cognitive function and diffusion tensor imaging were assessed in a group of 12 patients with early relapsing—remitting multiple sclerosis (disease duration ≤3 years), and mild clinical disability (expanded disability status scale ≤2), as well as in 12 control subjects. Patients showed impairment in immediate logical memory and delayed recall with the Rey auditory verbal learning test. No significant differences in classical executive tests were observed. In contrast, differences were found for specific executive tests including IOWA Gambling Task, multiple errands test hospital version (MET) and Hotel Task, as well as in Paced-Auditory Serial Addition Test (PASAT). Significant correlation was found between PASAT performance and FA measures ( r = 0.64, P = 0.03), the apparent diffusion coefficients and the MET ( r = 0.72, P = 0.01), as well as in one subtask of Hotel ( r = -0.68, P = 0.02). Thus, executive deficits can best be appreciated at early stages of MS when a more specific battery of tests is used for patient evaluation. In this series, test failures observed correlated with changes in fronto-subcortical fiber tracts. Multiple Sclerosis 2008; 14: 364—369. http://msj.sagepub.com
Hollow-cathode electron source with a fast gas valve (2002)

In this paper the parameters of a hollow-cathode electron source and generated electron beam are presented. A gas-puff valve is used to provide a sharp pressure gradient between the cathode cavity and the accelerating gap. Parameters of a He gas and the plasma inside the cathode and the accelerating gap studied by electrical and optical diagnostics for different gas pressure and an amplitude of the discharge current are presented. It was found that the operation of the HC is characterized by a negative anode potential fall and that the plasma density and temperature do not exceed 5/spl times/10/sup 12/ cm/sup -3/ and 14 eV, respectively. Parameters of the electron beam for different discharge current and anode grid cell sizes are presented. It was shown that efficient electron beam generation with an amplitude of the beam current up to 300 A does not lead to significant increase of the plasma potential. The results of the simulation of the HC operation agree with the obtained data.
Accountable Internet of Things? Outline of the IoT databox model (2017)

© 2017 IEEE. This paper outlines the IoT Databox model as a means of making the Internet of Things (IoT) accountable to individuals. Accountability is a key to building consumer trust and mandated in data protection legislation. We briefly outline the 'external' data subject accountability requirement specified in actual legislation in Europe and proposed legislation in the US, and how meeting requirement this turns on surfacing the invisible actions and interactions of connected devices and the social arrangements in which they are embedded. The IoT Databox model is proposed as an in principle means of enabling accountability and providing individuals with the mechanisms needed to build trust in the IoT.
Advanced Coolant Temperature Control Study With Integrated Thermal Management System Valve (2021)

Objective of the vehicle thermal management system is to achieve precise coolant temperature control that ensures operation of the combustion engine in the region with the maximum thermal efficiency. In this study it is achieved by a combined effect of coolant temperature control algorithm that is operating an advanced electronic valve with one input and three outputs that balances distribution of the coolant flow between the heat source and sink components. The objective is to present an application of a nonlinear model predictive control (NMPC) approach for coolant temperature control. It is a simulation study to quantify benefits of precise coolant temperature control with the possible inclusion of preview information.
Preferential synthesis of the 78-Kd glucose-regulated protein in glucocorticoid-treated S49 mouse lymphoma cells (1992)

To investigate the mechanism of glucocorticoid-induced lymphocytolysis, we used two-dimensional gel electrophoresis to analyze the effect of dexamethasone on the synthesis of individual proteins in S49 mouse lymphoma cells. We found that synthesis of a 78-Kd protein is preferentially maintained following dexamethasone treatment, at a time when the synthesis of most other cellular proteins is decreased. Synthesis of this protein could also be induced by tunicamycin, suggesting that it might be the 78-Kd glucose-regulated protein (GRP78). The identity of the 78-Kd protein with GRP78 was confirmed by limited chymotryptic mapping and immunoprecipitation analysis. Preferential synthesis of GRP78 in dexamethasone-treated cells was not secondary to alterations in the glycosylation of cellular proteins. Significantly, steady-state levels of GRP78 mRNA were unchanged following dexamethasone treatment. Preferential synthesis of GRP78 in glucocorticoid-treated S49 cells may reflect the unique property of GRP78 mRNA to be translated under conditions that interfere with the translation of most other cellular mRNAs. GRP78 is a highly conserved protein that is essential for cell viability. Preferential synthesis of GRP78 may be a protective response to metabolic events that interfere with normal mRNA translation in glucocorticoid-treated mouse lymphoma cells.
A Chronic Toxicity Study of the Ground Root Bark of Capparis erythrocarpus (Cappareceae) in Male Sprague-dawley Rats (2013)

The safety evaluation of Capparis erythrocarpus (CE) on chronic administration at 18 and 180 mg kg(-1) body weight for 6 months was investigated in male Sprague-Dawley rats. The effects of CE on certain serum biochemical, haematological, urine and histopathological determinations were used as indices of organ specific toxicity. Also the effects of CE on rat blood clotting time and pentobarbital-induced sleeping time were determined. Results indicate that CE had no effect on urine, haematological and serum biochemical indices at termination of treatment with the exception of serum ALT level which was significantly (p < 0.05) attenuated in a dose-dependent fashion (21-35%). There were also no differences in blood clotting time and pentobarbital-induced sleeping time between CE-treated and control animals. Histopathological studies showed that CE did not adversely affect the morphology of the liver, kidney and heart tissues. However, lungs of CE-treated animals showed slight but insignificant inflammatory response in alveolar areas and Clara cell hyperplasia without the thickening of alveolar septa and bronchiolar epithelial wall. Organ weights were not adversely affected by CE treatment. There were significant (p < 0.05) changes in weight of CE-treated animals with duration of treatment compared to control. These results suggest that there is no organ specific toxicity associated with chronic administration of CE in rats and its ability to reduce body weight may be useful for slimming in obese persons.
ChemInform Abstract: Activation and Synthetic Applications of Thiostannanes. A New Method for Synthesis of Thio‐ and Selenoglycosides. (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
X Chromosome-Linked IRAK-1 Polymorphism Is a Strong Predictor of Multiple Organ Failure and Mortality Postinjury (2014)

The IRAK1 polymorphism is a strong independent predictor of MOF and mortality postinjury and represents a common variant with prognostic potential. These data demonstrate the importance of TLR signaling postinjury and supports that a genetic mechanism may drive sex outcome differences postinjury.
NRF2 Blockade Suppresses Colon Tumor Angiogenesis by Inhibiting Hypoxia-Induced Activation of HIF-1α (2011)

Transcription factor NRF2 is an important modifier of cellular responses to oxidative stress. Although its cytoprotective effects are firmly established, recent evidence suggesting important roles in cancer pathobiology has yet to be mechanistically developed. In the current study, we investigated the role of NRF2 in colon tumor angiogenesis. Stable RNAi-mediated knockdown of NRF2 in human colon cancer cells suppressed tumor growth in mouse xenograft settings with a concomitant reduction in blood vessel formation and VEGF expression. Similar antiangiogenic effects of NRF2 knockdown were documented in chick chorioallantoic membrane assays and endothelial tube formation assays. Notably, NRF2-inhibited cancer cells failed to accumulate HIF-1α protein under hypoxic conditions, limiting expression of VEGF and other HIF-1α target genes. In these cells, HIF-1α was hydroxylated but pharmacological inhibition of PHD domain-containing prolyl hydroxylases was sufficient to restore hypoxia-induced accumulation of HIF-1α. Mechanistic investigations demonstrated that reduced mitochondrial O(2) consumption in NRF2-inhibited cells was probably responsible for HIF-1α degradation during hypoxia; cellular O(2) consumption and ATP production were lower in NRF2 knockdown cells than in control cells. Our findings offer novel insights into how cellular responses to O(2) and oxidative stress are integrated in cancer cells, and they highlight NRF2 as a candidate molecular target to control tumor angiogenesis by imposing a blockade to HIF-1α signaling.
Wide bandwidth measurement of complex permittivity of liquids using coplanar lines (2001)

A technique for measurement of complex permittivity of dielectric materials, using coplanar waveguide cells is presented. A complete solution of the forward and inverse problems, based on a quasi-TEM propagation model, is given. Unlike other methods, our method allows solution of the inverse problem without the use of iterative or graphical techniques. The model accounts for the various discontinuities along the line. Several advantages result from this approach. Measurement over a broad frequency range is possible, limited only by dispersive effects. It is suitable for solids not amenable to machining for cavity measurements, and there need not be any contact.
Association of subchondral bone texture on magnetic resonance imaging with radiographic knee osteoarthritis progression: data from the Osteoarthritis Initiative Bone Ancillary Study (2018)

• Subchondral bone MRI texture analysis is a promising knee osteoarthritis imaging biomarker. • In this study, subchondral bone texture was associated with knee osteoarthritis progression. • This demonstrates predictive and concurrent validity of MRI subchondral bone texture analysis. • This method may be useful in clinical trials with interventions targeting bone.
Detection of trace nitrogen in bulk argon using proton transfer reactions (1998)

Atmospheric pressure chemical ionization mass spectrometry (APCI-MS) is being routinely used to quantify trace impurities in bulk gases used in the manufacture of semiconductor devices. APCI-MS has been successfully applied for the quantification of ppt (ng/Kg) levels of O2, H2O, CO2 and CH4 in Ar, N2 and He and trace N2 in He. However it has not been successfully used to quantify ppt levels of N2 in Ar due to unfavorable rate constant for the charge transfer reaction between Ar+ and N2. We report here the detection of ppt levels of N2 in Ar by adding a few percent of purified H2 into the ionization source of the mass spectrometer. The addition of H2 results in a plasma dominated by protonated ions and the detection of trace N2 is facilitated by favorable proton transfer reactions to produce N2H+. Our experimental results indicate statistical detection limits below 50 ppt.
Diameter Credit Control Interoperability Test Suite (2009)

This document describes a collection of test cases to be used for
Diameter Credit Control application interoperability testing.
A model for the Escherichia coli FtsB/FtsL/FtsQ cell division complex (2011)

The two models obtained for the FtsB/FtsL/FtsQ complex were stable and thus compatible with the in vivo periplasmic complex structure. Although the hexameric model 2:2:2 has features that indicate that this is the most plausible structure, the ternary complex 1:1:1 cannot be discarded. Both models could be further stabilized by the binding of the other proteins of the divisome. The bioinformatics modelling of this kind of protein complex, whose function is mainly structural, provide useful information. Experimental results should confirm or reject these models and provide new data for future bioinformatics studies to refine the models.
ChemInform Abstract: Chromium‐Substituted Aluminophosphate‐5: A Recyclable Catalyst for the Selective Oxidation of Secondary Alcohols. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Dry reforming of methane over a Ni/Al2O3 catalyst in a coaxial dielectric barrier discharge reactor (2011)

A coaxial double dielectric barrier discharge (DBD) reactor is developed for plasma-catalytic conversion of CH 4 and CO 2 into syngas and other valuable products. A supported metal catalyst (Ni/Al 2 O 3 ) reduced in a methane discharge is fully packed into the discharge region. The influence of the Ni/Al 2 O 3 catalyst packed into the gas gap on the electrical characteristics of the discharge is investigated. The introduction of the catalyst pellets leads to a transition in discharge behaviour from a typical filamentary microdischarge to a combination of spatially limited microdischarges and a predominant surface discharge on the catalyst surface. It is also found that the breakdown voltage of the CH 4 /CO 2 discharge significantly decreases when the reduced catalyst is fully packed in the discharge area. Conductive Ni active sites dispersed on the catalyst surface contribute to the expansion of the discharge and enhancement of charge transfer. In addition, plasma-catalytic dry reforming of CH 4 is carried out with the reduced Ni/Al 2 O 3 catalyst using a mixing ratio of CH 4 /CO 2 = 1 and a total flow rate of 50 ml min −1 . An increase in H 2 selectivity is observed compared with dry CH 4 reforming with no catalyst, while the H 2 /CO molar ratio significantly increases from 0.84 to 2.53 when the catalyst is present.
Thin minimal rim width at Bruch&rsquo;s membrane opening is associated with glaucomatous paracentral visual field loss (2017)

Thin minimal BMO-MRW may represent a new structural biomarker associated with early glaucomatous paracentral VF loss.
Promoting axonal regeneration in the central nervous system by enhancing the cell body response to axotomy (2002)

Neurons projecting into the peripheral nervous system (PNS) regenerate their axons after injury, in contrast to those confined to the central nervous system (CNS). Both neuronal and nonneuronal factors contribute to the lack of CNS regeneration. In this review we concentrate on the differential gene expression response to axotomy in PNS vs. CNS neurons. In general CNS neurons fail to up-regulate or sustain the expression of regeneration-associated proteins (RAGs), including trophic factors and their receptors. The presumed lack of trophic support of axotomized CNS neurons provided the rationale for the exogenous application of trophic factors, either to the lesion site or to the cell bodies. Here, we review our data on the application of trophic factors to rubrospinal and corticospinal neurons. Cell body treatment of axotomized rubrospinal neurons with brain-derived neurotrophic factor (BDNF) reversed atrophy, increased GAP-43 and Talpha-1 tubulin mRNA expression, and promoted axonal regeneration into peripheral nerve grafts. Importantly, BDNF cell body treatment was still effective in the chronic setting, i.e., when initiated 1 year after injury, but BDNF had no effect when applied to the chronic spinal cord injury site. The ability to promote regeneration in chronically injured neurons will hopefully contribute to the development of treatment strategies for chronic spinal injuries.
Effects of in vitro prepared immune complexes on rat adipose tissue lipoprotein lipase. (1989)

The possibility that circulating immune complexes (IC) could modify lipoprotein lipase (LPL) activity or release was explored in in vitro systems. IC were precipitated at antibody-Ag equivalence by using specific rabbit antisera and Ag from inactivated rubella virus and hemagglutinins from purified whole virions from three prototype strains of influenza (A/Brazil, A/Bangkok, and B/Singapore) as well as from a combined diphtheria and tetanus toxoid adsorbed with inactivated pertussis. After resolubilization, these IC were exposed to delipidated homogenates of rat epididymal fat pads before assay for LPL activity. LPL activity was stimulated two- to three-fold by the presence of 20 to 40 micrograms IC protein. This effect is not caused by the individual components of the IC because neither the specific Ag nor the individual antisera had any significant effect on LPL activity. With the rubella IC, a greater stimulatory effect was seen with increase in IC protein. With the influenza and diphtheria, pertussis, tetanus (DPT) IC, however, inhibition occurred when IC protein exceeded the amount of protein used for the LPL assay. C did not appear to be involved because IC prepared with heated antisera had similar effects. When intact rat epididymal fat pads were exposed to the rubella, influenza, or DPT IC, LPL activity recovered in the suspension medium was increased in each instance compared with pads exposed to a comparable amount of albumin. These findings may have implications for specific lipid changes that may occur during the immediate post-infectious period following rubella, influenza, or infections with the several bacteria whose Ag were present in the DPT IC used in these studies.
Joint network-channel code optimization for wireless sensor networks (2013)

Abstract Optimization of sensor network architecture in order to improve the overall system performance at the end processing station is an important challenge. A lot of architectures have been designed to optimize the bit error rate. Conventionally, this optimization is done by inserting relays between sensors and destination. These relays insert redundant information by mixing the incoming streams from sensor nodes, hence creating parity check information which is very useful to help decode the transmit information from sensors. The goal is to combine network and channel coding to match network on graph to code on graph, and this is called adaptive network coded cooperation (ANCC). Compared to the previous works in the field, we propose a new transmit protocol based on the use of beamforming technique which is very efficient in terms of throughput and is fully compatible with the physical network coding (PNC) principles. Furthermore, we propose a distributed coding scheme where the relay, the destination, and the sensors are all equipped with repeat accumulate (RA) channel code structures. The relay has a special RA structure to suit the need of the PNC multiple access channel.
Velvet-Noise Feedback Delay Network (2020)

Artificial reverberation is an audio effect used to simulate the acoustics of a space while controlling its aesthetics, particularly on sounds recorded in a dry studio environment. Delay-based methods are a family of artificial reverberators using recirculating delay lines to create this effect. The feedback delay network is a popular delay-based reverberator providing a comprehensive framework for parametric reverberation by formalizing the recirculation of a set of interconnected delay lines. However, one known limitation of this algorithm is the initial slow build-up of echoes, which can sound unrealistic, and overcoming this problem often requires adding more delay lines to the network. In this paper, we study the effect of adding velvet-noise filters, which have random sparse coefficients, at the input and output branches of the reverberator. The goal is to increase the echo density while minimizing the spectral coloration. We compare different variations of velvet-noise filtering and show their benefits. We demonstrate that with velvet noise, the echo density of a conventional feedback delay network can be exceeded using half the number of delay lines and saving over 50% of computing operations in a practical configuration using low-order attenuation filters.
Early-phase [18F]PI-2620 tau-PET imaging as a surrogate marker of neuronal injury (2020)

Early-phase imaging of [<sup>18</sup>F]PI-2620 can serve as a surrogate biomarker for neuronal injury. Dynamic imaging or a dual time-point protocol for tau-PET imaging could supersede additional [<sup>18</sup>F]FDG-PET imaging by indexing both the distribution of tau and the extent of neuronal injury.
CAN WE USE TWITTER FOR EDUCATIONAL ACTIVITIES (2008)

Abstract: Twitter is the most popular microblogging application, with almost one million users called twitterers, who can send and receive messages via the web, SMS, instant messaging clients, and by third party applications. Posts are limited to 140 text characters in length. With a solid experience in using Web2.0 technologies in education, the authors are trying to provide arguments for using Twitter as microblogging platform / social network in education, underlining its advantages, but also possible bad points. The article presents too an application related to the Romanian Twitosphere and a Romanian microblogging platform, already used in education.
DCT based multiple hashing technique for robust audio fingerprinting (2009)

Audio fingerprinting techniques should successfully perform content-based audio identification even when the audio files are slightly or seriously distorted. In this paper, we present a novel audio fingerprinting technique based on combining fingerprint matching results for multiple hash tables in order to improve the robustness of hashing. Multiple hash tables are built based on the discrete cosine transform (DCT) which is applied to the time sequence of energies in each sub-band. Experimental results show that the recognition errors are significantly reduced compared with Philips Robust Hash (PRH) under various distortions.
AIROX nuclear fuel recycling and waste management (1993)

This report discusses the AIROX process which is a dry pyrochemical process developed by Atomic International for recycling LWR spent fuels which would retain most of the fission-product inventory in reconstituted fuel assemblies. The process would: (1) avoid the generation of high-level liquid waste streams, (2) recycle fertile U-238, unburned U-235, and unburned transuranics, and, (3) in principle, allow extended burnup to about 120 MWd/kg via three or four recycles. In this study: (1) prior AIROX studies were reviewed, (2) a preconceptual design and cost estimate of an AIROX plant were developed, (3) types and amounts of wastes that would be generated were calculated, and (4) further R&D needs for the AIROX process were identified.
Localization by fluorescence in situ hybridization (FISH) of human mitochondrial polymerase γ (POLG) to human chromosome band 15q24→q26, and of mouse mitochondrial polymerase γ (<i>Pol</i><i>g</i>) to mouse chromosome band 7E, with confirmation by direct sequence analysis of bacterial artificial chromosomes (BACs) (1997)

Cloned cDNAs for the human mitochondrial DNA polymerase gamma (POLG) were identified by homology with the yeast mitochondrial DNA polymerase catalytic subunit (MIP). Fluorescence in situ hybridization (FISH) of human and mouse bacterial artificial chromosomes (BACs), hybridized by radioactively labeled POLG cDNAs, mapped to human chromosome band 15q24-->q26, as well as to mouse chromosome band 7E. Direct sequencing of the BAC DNA without subcloning confirmed the presence of both human POLG and mouse mitochondrial DNA polymerase gamma (Polg) in the respective BACs.