gebhart/patrepeval huggingface dataset:
Design for Conveying Piping of SCGP Pulverized Coal (2006)

Process flow was introduced for pulverized coal preparation and feed conveying system in coal gasification technology,in combination with project construction experience,the piping design gists were discussed for pulverized coal preparation,pressurization and feeding systems,relative matters to be noticed were indicated in piping design.
Least squares image matching for oblique images based on non-fixed initial patch (2014)

Welcome to the WIT Press eLibrary - the home of the Transactions of the Wessex Institute collection, providing on-line access to papers presented at the Institute's prestigious international conferences and from its State-of-the-Art in Science & Engineering publications.
Underlay CR-NOMA Relaying Networks over Non-Homogeneous Generalized Fading Channels (2020)

In this paper, we studied a decode-and-forward underlay cognitive radio non-orthogonal multiple access (CR-NOMA) relaying system over non-homogeneous generalized alpha-mu fading channels. We derived accurate analytical expressions in closed form of the outage probability (OP) for two secondary end-users (E1 and E2). We considered three special cases of the alpha-mu statistical model. Moreover, we evaluated the impact of several system and fading parameters on the OP performance of the considered CR-NOMA. We also obtained simplified closed-form approximations to gain useful insights on the system performance. Finally, the analysis is verified by the good agreement with Monte Carlo simulations.
Simultaneous Estimation of Withaferin A and Z-Guggulsterone in Marketed Formulation by RP-HPLC (2015)

A simple, rapid, precise and accurate high-performance liquid chromatography (HPLC) method was developed for simultaneous estimation of withaferin A and Z-guggulsterone in a polyherbal formulation containing Withania somnifera and Commiphora wightii. The chromatographic separation was achieved on a Purosphere RP-18 column (particle size 5 µm) with a mobile phase consisting of Solvent A (acetonitrile) and Solvent B (water) with the following gradients: 0-7 min, 50% A in B; 7-9 min, 50-80% A in B; 9-20 min, 80% A in B at a flow rate of 1 mL/min and detection at 235 nm. The marker compounds were well separated on the chromatogram within 20 min. The results obtained indicate accuracy and reliability of the developed simultaneous HPLC method for the quantification of withaferin A and Z-guggulsterone. The proposed method was found to be reproducible, specific, precise and accurate for simultaneous estimation of these marker compounds in a combined dosage form. The HPLC method was appropriate and the two markers are well resolved, enabling efficient quantitative analysis of withaferin A and Z-guggulsterone. The method can be successively used for quantitative analysis of these two marker constituents in combination of marketed polyherbal formulation.
Mise en evidence d'un processus d'agrégation par filtration de solutions aqueuses d'hydroxyéthylcellulose (1985)

Les propriétés de filtrabilité des solutions d'hydroxyéthylcellulose à travers les milieux poreux dépendent essentiellement de leur concentration et de la température. Des mesures de diffusion de la lumière montrent que dans certaines conditions de concentration et de porosité des filtres, la filtration peut induire une agrégation thermoréversible des chaînes qui n'est que partiellement à l'origine des phénomènes de colmatage. Les agrégats dont la proportion est très faible sont très compacts et proviennent probablement d'une association interchaine de type cellulosique par l'intermédiaire des motifs anhydroglucose non substitués.
Synthesis, Chiral Resolution, and Absolute Configuration of C2‐Symmetric, Chiral 9,9′‐Spirobifluorenes (2014)

Abstract Racemic 2,2′‐, 2,2′,7,7′‐, and 2,2′,3,3′‐substituted 9,9′‐spirobifluorenes were synthesised and successfully resolved by HPLC on a Chiralpak IA stationary phase on both analytical and semipreparative scales. Their absolute configurations were determined by comparison of their specific optical rotations with literature data or by comparison of retention times with independently prepared enantiopure material. These compounds are versatile C 2 ‐symmetric building blocks for the formation of more sophisticated cleft‐like, chiral molecular architectures.
A haptic display for tactile and kinesthetic feedback in a CHAI 3D palpation training scenario (2015)

Robot-assisted minimally invasive surgery generally prevents the use of an important diagnostic tool in medicine: palpation. There are various approaches to reestablish the haptic feedback for the surgeon, including tactile displays and haptic input devices. We present a novel haptic display that features seven pins mounted on compression springs that can be pre-loaded with servo motors. Each pin has a stroke of 10 mm and a maximum counterforce of 1.1 N. An additional force of 0.7 N per pin can be applied with the motors. This technique allows for simultaneous stimulation of kinesthetic as well as tactile perception. The control of the haptic display has been implemented in the open-source haptics library CHAI 3D. We extended the framework with a multi interaction point tool to represent the hardware. This eventually lead to a palpation training program where bodies with multiple adjustable parameters encapsulated in a virtual soft tissue can be simulated. We evaluated this software in a user study with 15 participants in order to demonstrate the usability of the haptic display. With 90 % of successful hits, we are confident that sensible haptic feedback can be generated with the presented device. Furthermore, we are currently extending the scope of the haptic display to make use of a novel capacitive tactile proximity sensor in exploration scenarios.
Progress in the characterization of synthetic (supramolecular) polymers by analytical ultracentrifugation (2006)

Analytical ultracentrifugation (AUC) is the leading technique for determining the molar mass, state of association in solution, and association constants of biological macromolecules. Even though it is little used for supramolecular polymers, this technique has already been shown to represent one of the best options in the characterization of these systems. The use of supramolecular assemblies in the field of nanotechnology requires the arrangement of such systems on surfaces, from solution. Therefore, the control and investigation of solution properties is of major importance. In this contribution we highlight the applicability and advantages of using AUC by presenting a summary of the results of the past few years on the characterization of various types of synthetic polymers and supramolecular polymer systems.
Zoonotic infections with avian influenza A viruses and vaccine preparedness: a game of "mix and match" (2014)

Various direct avian-to-human transmissions of influenza A virus subtypes upon exposure to infected poultry have been previously observed in the past decades. Although some of these strains caused lethal infections, the lack of sustained person-to-person transmission has been the major factor that prevented these viruses from causing new pandemics. In 2013, three (A/H7N9, A/H6N1, and A/H10N8) novel avian influenza viruses (AIVs) yet again breached the animal-human host species barrier in Asia. Notably, roughly 20% of the A/H7N9-infected patients succumbed to the zoonotic infection whereas two of three A/H10N8 human infections were also lethal. Thus, these events revived the concerns of potential pandemic threats by AIVs in the horizon. This article reviews the various human incursions with AIV variants and provides insight on how continued circulation of these viruses poses perpetual challenge to global public health. As the world anticipates for the next human pandemic, constant vigilance for newly emerging viruses in nature is highly encouraged. With the various numbers of AIVs demonstrating their capacity to breach the animal-human host interface and apparent limitations of current antivirals, there is a need to broaden the selection of pre-pandemic vaccine candidate viruses and development of novel alternative therapeutic strategies.
Full-Field Calcium K-Edge X-ray Absorption Near-Edge Structure Spectroscopy on Cortical Bone at the Micron-Scale: Polarization Effects Reveal Mineral Orientation (2016)

Here, we show results on X-ray absorption near edge structure spectroscopy in both transmission and X-ray fluorescence full-field mode (FF-XANES) at the calcium K-edge on human bone tissue in healthy and diseased conditions and for different tissue maturation stages. We observe that the dominating spectral differences originating from different tissue regions, which are well pronounced in the white line and postedge structures are associated with polarization effects. These polarization effects dominate the spectral variance and must be well understood and modeled before analyzing the very subtle spectral variations related to the bone tissue variations itself. However, these modulations in the fine structure of the spectra can potentially be of high interest to quantify orientations of the apatite crystals in highly structured tissue matrices such as bone. Due to the extremely short wavelengths of X-rays, FF-XANES overcomes the limited spatial resolution of other optical and spectroscopic techniques exploiting visible light. Since the field of view in FF-XANES is rather large the acquisition times for analyzing the same region are short compared to, for example, X-ray diffraction techniques. Our results on the angular absorption dependence were verified by both site-matched polarized Raman spectroscopy, which has been shown to be sensitive to the orientation of bone building blocks and by mathematical simulations of the angular absorbance dependence. As an outlook we further demonstrate the polarization based assessment of calcium-containing crystal orientation and specification of calcium in a beta-tricalcium phosphate (β-Ca3(PO4)2 scaffold implanted into ovine bone. Regarding the use of XANES to assess chemical properties of Ca in human bone tissue our data suggest that neither the anatomical site (tibia vs jaw) nor pathology (healthy vs necrotic jaw bone tissue) affected the averaged spectral shape of the XANES spectra.
Human Sulfotransferases and Their Role in Chemical Metabolism (2005)

Sulfonation is an important reaction in the metabolism of numerous xenobiotics, drugs, and endogenous compounds. A supergene family of enzymes called sulfotransferases (SULTs) catalyze this reaction. In most cases, the addition of a sulfonate moiety to a compound increases its water solubility and decreases its biological activity. However, many of these enzymes are also capable of bioactivating procarcinogens to reactive electrophiles. In humans three SULT families, SULT1, SULT2, and SULT4, have been identified that contain at least thirteen distinct members. SULTs have a wide tissue distribution and act as a major detoxification enzyme system in adult and the developing human fetus. Nine crystal structures of human cytosolic SULTs have now been determined, and together with site-directed mutagenesis experiments and molecular modeling, we are now beginning to understand the factors that govern distinct but overlapping substrate specificities. These studies have also provided insight into the enzyme kinetics and inhibition characteristics of these enzymes. The regulation of human SULTs remains as one of the least explored areas of research in the field, though there have been some recent advances on the molecular transcription mechanism controlling the individual SULT promoters. Interindividual variation in sulfonation capacity may be important in determining an individual's response to xenobiotics, and recent studies have begun to suggest roles for SULT polymorphism in disease susceptibility. This review aims to provide a summary of our present understanding of the function of human cytosolic sulfotransferases.
280 W output power single-ended amplifier using single-die GaN-FET for W-CDMA cellular base stations (2005)

A single-ended amplifier using a single-die GaN-FET was successfully developed for W-CDMA cellular base-station systems. The developed amplifier delivers a peak saturated output power of 280 W with a linear gain of 12.6 dB at a drain voltage of 48 V under 2.15 GHz 3GPP W-CDMA signal input. It is believed that the 280 W output power is the record output power in sigle-ended amplifiers at 2 GHz band. A high drain efficiency of 29% is also obtained at 8 dB power back off from the saturated output power.
Enhancement of spontaneous killer cytotoxicity by soluble factor. (1980)

Two-stage stimulation of SK activity of normal human peripheral blood lymphocytes by soluble factors was demonstrated. The first stage was initiated by factors present in supernatant derived from normal B-LCL cultures. Only cell lines which could induce SK activity in culture in an MLR-type reaction had the capacity to produce the active factor. Supernatant factor required adherent cells to cause SK augmentation. The interaction of adherent cells plus supernatant factor resulted in the production of a second soluble factor which stimulated an increase in SK activity in responding lymphocyte populations. This second stage involved a different soluble factor which acted directly on the non-SK, Fc-negative lymphocyte population, and within 3 hr. Data obtained using antisera to interferon (IF) indicated that IF is a component of the second soluble factor, and not of the supernatant factor derived from the B-LCL.
Efficient optical modeling of spontaneous emission in a cylindrically layered nanostructure (2007)

We present an efficient optical model to study spontaneous emission in a cylindrically layered nanostructure. The total emission power of an emitter in the nanostructure is efficiently calculated. A formula is derived to calculate the lateral-surface emission power. As examples of practical interest, spontaneous emission properties, including radiative transition rate of the emitter, the assignment of the emission to lateral-surface emission and waveguided emission, are comprehensively studied at the first time for an isolated ZnO nanowire and a ZnO/SiO(2) nanocable.
High resolution mass spectrometry. Bufadienolides—II. (1972)

Abstract Complete low resolution mass spectra and high resolution data for selected important peaks are presented and discussed for a series of naturally occurring 14β, 15β‐epoxybufadienolides (toad poisons) and their derivatives. The compounds examined were resibufogenin, marinobufagin, cinobufagin, desacetylcinobufagin, cinobufotalin, desacetylcinobufotalin and resibufagin, and the derivatives were 11α‐hydroxyresibufogenin, 3β‐acetoxymarinobufagin, 3‐ketocinobufagin, 3β‐acetoxy‐16β‐desacetylcinobufagin, 3β‐acetoxy‐16‐ketocinobufagin, resibufaginol, 14α‐artebufogenin and 3β‐suberyloxyresibufogenin methyl ester. The relatively unsaturated 2‐pyrone group of C‐17β has been used as an integral label to distinguish (from elemental composition data) ions containing it from those arising in other parts of the molecule that do not, and the spectra are interpreted in terms of structural ‘ion types’.
Comparison of Cytoreductive Surgery and Resection of Isolated Peritoneal Metastases in Patients with Peritoneal Metastases from Colorectal Cancer: A Retrospective Study (2023)

Cytoreductive surgery was not superior in providing long-term survival benefits for colorectal cancer peritoneal metastases; however, cytoreductive surgery provided a higher complete resection rate even in patients with a high peritoneal cancer index (6 points or higher).
Automatic evolution tracking for tennis matches using an HMM-based architecture (2005)

Creating a cognitive vision system which infers high-level semantic information from low-level feature and event information for a given type of multimedia content is a problem attracting many researchers' attention in recent years. In this work, we address the problem of automatic interpretation and evolution tracking of a tennis match using standard broadcast video sequences as input data. The use of a hierarchical structure consisting of hidden Markov models is proposed. This takes low-level events as its input and produce an output where the final state indicates if the point is to be awarded to one player or another. Using ground-truth data as input for the classifier described, the points are always correctly awarded to the players. Even when modifying the ground-truth data with errors randomly inserted in it and use it as input for the proposed system, the system performance degraded gracefully
Late extensive intravenous administration of N-acetylcysteine can reverse hepatic failure in acetaminophen overdose (2010)

Acetaminophen is a commonly used analgesic and has been shown to be a main cause of drug-induced liver failure. N-acetylcysteine (NAC) should be employed as the antidote in case of acetaminophen poisoning within the first 8-10 hours. Oral administration of NAC is universally recommended and due to the adverse effects, the intravenous administration of the agent is reserved for patients with oral intolerance and severe complications. We here report an 18-year-old man with severe liver failure due to a huge ingestion of acetaminophen, who was taken into the Loghman Hakim Hospital Poison Center 72 hours after attempted suicide. Regarding the poor prognostic clues as his level of consciousness and impaired liver functions, an extensive intravenous regimen of NAC was started. The patient survived the condition with an additional intravenous administration of NAC past the first 72 hours of treatment. We discuss that even in late phases of intoxication; high-dose intravenous NAC can serve a substantial improvement.
Identification of specific EP receptors responsible for the hemodynamic effects of PGE2 (1999)

To identify the E-prostanoid (EP) receptors that mediate the hemodynamic actions of PGE2, we studied acute vascular responses to infusions of PGE2 using lines of mice in which each of four EP receptors (EP1 through EP4) have been disrupted by gene targeting. In mixed groups of males and females, vasodepressor responses after infusions of PGE2 were significantly diminished in the EP2 -/- and EP4 -/- lines but not in the EP1 -/- or EP3 -/- lines. Because the actions of other hormonal systems that regulate blood pressure differ between sexes, we compared the roles of individual EP receptors in males and females. We found that the relative contribution of each EP-receptor subclass was strikingly different in males from that in females. In females, the EP2 and EP4 receptors, which signal by stimulating adenylate cyclase, mediate the major portion of the vasodepressor response to PGE2. In males, the EP2 receptor has a modest effect, but most of the vasodepressor effect is mediated by the phospholipase C-coupled EP1 receptor. Finally, in male mice, the EP3 receptor actively opposes the vasodepressor actions of PGE2. Thus the hemodynamic actions of PGE2 are mediated through complex interactions of several EP-receptor subtypes, and the role of individual EP receptors differs dramatically in males from that in females. These differences may contribute to sexual dimorphism of blood pressure regulation.
Ectopic relapse of IgG4-related disease presenting as IgG4-related sclerosing cholecystitis (2018)

There are 2 major types of IgG4-related cholecystitis, a diffuse wall thickening type and a mass formation type. It is sometimes difficult to differentiate IgG4-related cholecystitis with gallbladder cancer.Corticosteroid (CS) is effective for induction of remission; however, we sometimes encounter disease relapse after reduction of CS dose. We should be mindful that some patients may relapse with new organ involvements even if the primary site and serum IgG4 level are well controlled.
Economic and Nonproliferation Analysis Framework for Assessing Reliable Nuclear Fuel Service Arrangements (2010)

Nuclear power is now broadly recognized as an essential technology in national strategies to provide energy security while meeting carbon management goals. Yet a long standing conundrum remains: how to enable rapid growth in the global nuclear power infrastructure while controlling the spread of sensitive enrichment and reprocessing technologies that lie at the heart of nuclear fuel supply and nuclear weapons programs. Reducing the latent proliferation risk posed by a broader horizontal spread of enrichment and reprocessing technology has been a primary goal of national nuclear supplier policies since the beginning of the nuclear power age. Attempts to control the spread of sensitive nuclear technology have been the subject of numerous initiatives in the intervening decades sometimes taking the form of calls to develop fuel supply and service assurances to reduce market pull to increase the number of states with fuel cycle capabilities. A clear understanding of what characteristics of specific reliable nuclear fuel service (RNFS) and supply arrangements qualify them as 'attractive offers' is critical to the success of current and future efforts. At a minimum, RNFS arrangements should provide economic value to all participants and help reduce latent proliferation risks posed by the global expansion of nuclear power.more » In order to inform the technical debate and the development of policy, Pacific Northwest National Laboratory has been developing an analytical framework to evaluate the economics and nonproliferation merits of alternative approaches to RNFS arrangements. This paper provides a brief overview of the economic analysis framework developed and applied to a model problem of current interest: full-service nuclear fuel leasing arrangements. Furthermore, this paper presents an extended outline of a proposed analysis approach to evaluate the non-proliferation merits of various RNFS alternatives.« less
Additional Structure in Bond Graph Modeling (1987)

In this paper, we investigate additional structure that might be put on bond graphs in order that (1) all bond graphs have physical realization and (2) all physical realizations have bond graphs. In particular, restrictions are proposed for the allowed forms for the constitutive laws and the modulation of elements. This added structure is proposed to ensure the existence of a unique energy state function, passivity of sourceless models, ensure unique solutions to the model equations, and preserve the signal or information nature of modulation.
An Activity-Dependent Neurotrophin-3 Autocrine Loop Regulates the Phenotype of Developing Hippocampal Pyramidal Neurons before Target Contact (2001)

Neurotrophin-3 (NT-3), its cognate receptor trkC, and voltage-gated calcium channels are coexpressed by embryonic pyramidal neurons before target contact, but their functions at this stage of development are still unclear. We show here that, in vitro, anti-NT-3 and anti-trkC antibodies blocked the increase, and NT-3 reversed the decrease in the number of calbindin-D(28k)-positive pyramidal neurons induced by, respectively, calcium channel activations and blockades. Similar results were obtained with single-neuron microcultures. In addition, voltage-gated calcium channel inhibition downregulates the extracellular levels of NT-3 in high-density cultures. Moreover, electrophysiological experiments in single-cell cultures reveal a tetrodotoxin-sensitive spontaneous electrical activity allowing voltage-gated calcium channel activation. The mouse NT-3 (-/-) mutation decreases by 40% the number of developing calbindin-D(28k)-positive pyramidal neurons, without affecting neuronal survival, both in vitro and in vivo. Thus, present results strongly support that an activity-dependent autocrine NT-3 loop provides a local, intrinsic mechanism by which, before target contact, hippocampal pyramidal-like neurons may regulate their own differentiation, a role that may be important during early CNS differentiation or after adult target disruption.