gebhart/patrepeval huggingface dataset:
Sesteralterin and Tricycloalterfurenes A–D: Terpenes with Rarely Occurring Frameworks from the Marine-Alga-Epiphytic Fungus Alternaria alternata k21-1 (2017)

A new sesterterpene, sesteralterin (1), four new meroterpenes, tricycloalterfurenes A-D (2-5), and a known meroterpene, TCA-F (6), were obtained from the culture extract of an Alternaria alternata strain (k21-1) isolated from the surface of the marine red alga Lomentaria hakodatensis. The structures and relative/absolute configurations of these compounds were identified by spectroscopic analyses, mainly including 1D/2D NMR, ECD, and mass spectra and quantum chemical calculations. Compound 1 represents the first nitidasane sesterterpene naturally produced by fungi, and 2-5 feature a tetrahydrofuran unit rarely occurring in tricycloalternarenes. Compounds 1-6 were assayed for inhibition of the growth of four marine plankton and one marine alga-pathogenic bacterium.
Mechanism of Proton Transfer in [FeFe]-Hydrogenase from Clostridium pasteurianum (2011)

[FeFe]-Hydrogenases are complex metalloproteins that catalyze the reversible reduction of protons to molecular hydrogen utilizing a unique diiron subcluster bridged to a [4Fe4S] subcluster. Extensive studies have concentrated on the nature and catalytic activity of the active site, yet relatively little information is available concerning the mechanism of proton transport that is required for this activity. Previously, structural characterization of [FeFe]-hydrogenase from Clostridium pasteurianum indicated a potential proton transport pathway involving four residues (Cys-299, Glu-279, Ser-319, and Glu-282) that connect the active site to the enzyme surface. Here, we demonstrate that substitution of any of these residues resulted in a drastic reduction in hydrogenase activity relative to the native enzyme, supporting the importance of these residues in catalysis. Inhibition studies of native and amino acid-substituted enzymes revealed that Zn(2+) specifically blocked proton transfer by binding to Glu-282, confirming the role of this residue in the identified pathway. In addition, all four of these residues are strictly conserved, suggesting that they may form a proton transport pathway that is common to all [FeFe]-hydrogenases.
Direct Myocardial Revascularization without Cardiopulmonary Bypass (1985)

The authors present their experience with 160 patients who underwent coronary artery saphenous vein bypass revascularization without cardiopulmonary bypass. The distal sutures were performed with interruption of the coronary flow without any devices for perfusion of the coronary artery: the proximal sutures were made with tangential clamping of the aorta. Vessels most frequently revascularized were the anterior descending and the distal right coronary artery. Out of 597 patients who underwent bypass surgery in this period, this technique could be employed in 160 cases (26.8%). Hospital mortality was 3.1% (5/160) and perioperative myocardial infarction as determined by daily EKGs and CKMB occurred in 4 patients (2.5%). Control hemodynamic studies were performed in 41 of the 160 patients (25.6%) with a patency rate of 83.9% in the 62 grafts restudied. We conclude that direct myocardial revascularization can be performed safely without major difficulties and with efficient anastomoses. The main advantages of the technique are that it does not require the use of extracorporeal circulation and, consequently, the use of any blood, as well as its low cost due to shorter hospitalization periods.
Advanced high definition 50 to 60 Hz standard conversion (1988)

The authors present an advanced method of performing standard conversion from 50 to 59.94 Hz at a high quality level. The starting point of this work is based on the European proposal of a unique world production standard based on 50 Hz (1152 active lines, 50 Hz, 1:1) and the desire to promote programmes produced according to this standard for use in high definition television (HDTV) in countries with both 50 and 59.94 Hz field rates.
Theoretical Studies of the Photolytic Decomposition of Vinyl Bromide at 193 nm (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTheoretical Studies of the Photolytic Decomposition of Vinyl Bromide at 193 nmGilbert J. Mains, Lionel M. Raff, and Samuel A. AbrashCite this: J. Phys. Chem. 1995, 99, 11, 3532–3539Publication Date (Print):March 1, 1995Publication History Published online1 May 2002Published inissue 1 March 1995https://pubs.acs.org/doi/10.1021/j100011a021https://doi.org/10.1021/j100011a021research-articleACS PublicationsRequest reuse permissionsArticle Views92Altmetric-Citations20LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
The Nature of Enhanced Natural Killer Lymphocyte Cytotoxicity During Anesthesia and Surgery in Patients with Benign Disease and Cancer (1984)

This study was instituted to determine the mechanism of enhanced natural killer (NK) lymphocyte activity during surgery. Natural cytotoxicity of whole blood to K562 target cells was assayed before anesthesia and during anesthesia and surgery in patients with benign and malignant gastrointestinal disease. Those patients with benign conditions and localized primary tumors showed enhanced NK lymphocyte cytotoxicity during surgery (p less than 0.025 and p less than 0.0025, respectively) but not patients with disseminated tumors. In patients with localized tumors, enhancement of NK lymphocyte cytotoxicity was an interferon-independent phenomenon but appeared to be related to a significant rise in the percentage of cells bearing the Leu 7 monoclonal antibody marker for NK cells (p less than 0.02). Exogenous leukocyte interferon caused further enhancement of NK cytotoxicity in patients with benign disease and some cancer patients. Enhancement of NK lymphocyte activity during surgery may be of significance in reducing tumor metastases by stimulation of natural cytotoxic mechanisms to circulating tumor emboli.
An omni-RGB+D camera rig calibration and fusion using unified camera model for 3D reconstruction (Withdrawal Notice) (2017)

International audience
Rapid, parallel path planning by propagating wavefronts of spiking\n neural activity (2012)

Efficient path planning and navigation is critical for animals, robotics,\nlogistics and transportation. We study a model in which spatial navigation\nproblems can rapidly be solved in the brain by parallel mental exploration of\nalternative routes using propagating waves of neural activity. A wave of\nspiking activity propagates through a hippocampus-like network, altering the\nsynaptic connectivity. The resulting vector field of synaptic change then\nguides a simulated animal to the appropriate selected target locations. We\ndemonstrate that the navigation problem can be solved using realistic, local\nsynaptic plasticity rules during a single passage of a wavefront. Our model can\nfind optimal solutions for competing possible targets or learn and navigate in\nmultiple environments. The model provides a hypothesis on the possible\ncomputational mechanisms for optimal path planning in the brain, at the same\ntime it is useful for neuromorphic implementations, where the parallelism of\ninformation processing proposed here can fully be harnessed in hardware.\n
Quantitative Seismic Attributes for Fractured Reservoir Characterisation (2010)

It is a considerable challenge to effectively produce from heterogeneous fractured reservoirs in a&lt;br&gt;complex structural setting. In this Middle Eastern onshore field the production comes mainly from&lt;br&gt;fractured igneous intrusive and metamorphic basement rocks and an overlying clastic formation. This&lt;br&gt;partially eroded and therefore heterogeneously distributed clastic formation can also have significant&lt;br&gt;fracturing. The presence of this clastic formation has a big impact on production of the drilled wells but&lt;br&gt;unfortunately it is below seismic resolution and therefore cannot be conventionally mapped on seismic.&lt;br&gt;The aim of this study was to detect fractured zones and to describe the distribution of the clastic&lt;br&gt;formation using seismic attributes calibrated to well information. A 400km2, high fold, wide-azimuth&lt;br&gt;seismic data set was acquired to provide an optimum illumination of the complex reservoir structure.&lt;br&gt;Azimuthal anisotropy from the wide-azimuth seismic survey proves to be one of the main productivity&lt;br&gt;indicators in this reservoir. Well production is quantitatively correlated with anisotropy intensity. In&lt;br&gt;some wells additional matrix porosity contributing to production is present in the heterogeneous&lt;br&gt;sandstone layer above the basement. The partially eroded sandstone layer can be detected with&lt;br&gt;seismic inversion. Therefore we find that a combination of these seismic attributes provides a powerful&lt;br&gt;tool to describe this complex reservoir. The attributes are used for well planning and reservoir modelling.
Non-Destructive Optical Characterization Tools (2008)

Fourier transform theory is one of the most widely
used tools in physical sciences to retrieve vital
information about various physical phenomena. In
general, because a Fourier transform is a complex
quantity, both its phase and magnitude are required
for a unique representation of the function of
interest. However, in many applications, only the
magnitude of the Fourier transform can be measured,
and a direct measurement of its phase is rather
difficult. This constitutes a fundamental limitation
in many fields, since the function of interest cannot
be recovered uniquely from its Fourier transform
magnitude measurement alone.
In this book, a special family of functions, so
called the minimum-phase functions, for which the
Fourier transform phase can be recovered from the
Fourier transform magnitude alone, is discussed. We
apply this concept to several important fields of
physics, and show in each case that with a simple
magnitude spectrum measurement and data processing,
we can recover the function of interest
unambiguously. In all cases, this approach has led to
significant breakthroughs, as well as simpler and
faster measurements and processing.
Application du procédé OM-CVD aux revêtements de céramiques sur acier : dépôts basse température de carbure de chrome à partir de bis (arene) chrome (1988)

En utilisant le procede de depot chimique a partir d'une phase gazeuse basse pression, des films de carbure de chrome ont ete obtenus entre 300 et 550**(o)c sur des substrats d'aciers, par pyrolyse du bis (isopropylbenzene) chrome (dcc) dans un reacteur a paroi chaude. La cinetique de croissance et la structure des depots ont ete etudies en fonction de la temperature. Le mecanisme de croissance a ete discute a partir de ces resultats. Des essais de corrosion en mode potentiodynamique, des tests de rayures et des mesures de microdurete ont permis de mettre en evidence les excellentes resistances a la corrosion et les bonnes proprietes mecaniques des films etudies
High-Dimensional Gaussian Graphical Model Selection: Walk Summability and Local Separation Criterion (2012)

We consider the problem of high-dimensional Gaussian graphical model selection. We identify a set of graphs for which an efficient estimation algorithm exists, and this algorithm is based on thresholding of empirical conditional covariances. Under a set of transparent conditions, we establish structural consistency (or sparsistency) for the proposed algorithm, when the number of samples n=omega(J_{min}^{-2} log p), where p is the number of variables and J_{min} is the minimum (absolute) edge potential of the graphical model. The sufficient conditions for sparsistency are based on the notion of walk-summability of the model and the presence of sparse local vertex separators in the underlying graph. We also derive novel non-asymptotic necessary conditions on the number of samples required for sparsistency.
Fire Resistant Study for Long Span Beams Made of FR 490 Steels (2016)

Building could be severely influenced by fire and it can be demolished so that the major structural elements such as columns and beams required to be coated by fire protection materials according to each condition. Especially, a steel framed building regarded as a weaken structures when the building is engulfed with a severe fire condition. Therefore, the fire resistant steel (FR 490) has been developed to improve the structural properties of an ordinary structural steels at high temperature. Generally, the fire resistance of structural beam built with a structural steel can be measured by horizontal furnace using a standard testing method by each nation’s standard. However, the real length of the beam showed the tendency longer than that of the horizontal furnace. Therefore, it is considered more important to know the real fire resistant performance of structural beams. In this paper, to evaluate the fire resistant performance of long span beams made of the FR 490, the fire engineering method is done using not only materials properties at high temperatures but a heat transfer, a stress theory. The results showed that as the length of beams are longer, the maximum load bearing capacities at high temperatures are lower and the deflections are increased.\n
New Light-Weight Crypto Algorithms for RFID (2007)

The authors propose a new block cipher, DESL (DES Lightweight extension), which is strong, compact and efficient. Due to its low area constraints DESL is especially suited for RFID(Radio Frequency Identification) devices. DESL is based on the classical DES (Data Encryption Standard) design, however, unlike DES it uses a single S-box repeated eight times. This approach makes it possible to considerably decrease chip size requirements. The S-box has been highly optimized in such a way that DESL resists common attacks, i.e., linear and differential cryptanalysis, and the Davies-Murphy-attack. Therefore DESL achieves a security level which is appropriate for many applications. Furthermore, we propose a light-weight implementation of DESL which requires 45% less chip size and 86% less clock cycles than the best AES implementations with regard to RFID applications. Compared to the smallest DES implementation published, our DESL design requires 38% less transistors. Our 0.18 <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">μm</i> DESL implementation requires a chip size of 7392 transistors (1848 gate equivalences) and is capable to encrypt a 64-bit plaintext in 144 clock cycles. When clocked at 100 kHz, it draws an average current of only 0.89 <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">μ</i> A. These hardware figures are in the range of the best eSTREAM streamcipher candidates, comprising DESL as a new alternative for ultra low-cost encryption
Study on Treatment of Slaughter Waste Water by IMBR Added Powdered Activated Carbon (2009)

The integrated membrane bioreactor(IMBR)was applied for treatment of slaughter waste water.The removal efficiencies of CODcr,BOD5 and [NH3-N] were investigated.The results show that the IMBR may achieve better removal efficiencies of CODcr,BOD5 and [NH3-N].The removal efficiencies of CODcr,BOD5 and [NH3-N] in the combined process are 95.45%,95.9% and 89.97% respectively.The effluent CODcr is 49.7 mg·L-1 and [NH3-N] is less than 10 mg·L-1.Meeting the first and second class criteria specified in integrated waste water discharge standard(GB 8978—1996).
Wheelchair push-ups: measuring pressure relief frequency. (1985)

Ischial pressure sores (PS) are a long-recognized complication of wheelchair confinement, yet teaching spinal-cord patients to establish lift-off behavior habitually and permanently remains a challenge. A new device was developed to record automatically and continuously the wheelchair lift-off behavior of spinal-cord injured patients. Data from seven patients who used the device for between 768 and 1800 hours each are reported. The device was used to monitor longitudinally the behavioral compliance of each individual with prescribed lift-off intervals using standard teaching procedures. Wide variability between patients and within patients over time was found. Experimental interventions including the use of an electronic timer and written and oral feedback of the previous day's data also varied in their effectiveness. Data from one patient who developed a pressure sore while being monitored suggest that there is no simple relationship between lift-off intervals and PS formation.
Time-Varying Signals Recovery Via Graph Neural Networks (2023)

The recovery of time-varying graph signals is a fundamental problem with numerous applications in sensor networks and forecasting in time series. Effectively capturing the spatiotemporal information in these signals is essential for the downstream tasks. Previous studies have used the smoothness of the temporal differences of such graph signals as an initial assumption. Nevertheless, this smoothness assumption could result in a degradation of performance in the corresponding application when the prior does not hold. In this work, we relax the requirement of this hypothesis by including a learning module. We propose a Time Graph Neural Network (TimeGNN) for the recovery of time-varying graph signals. Our algorithm uses an encoder-decoder architecture with a specialized loss composed of a mean squared error function and a Sobolev smoothness operator. TimeGNN shows competitive performance against previous methods in real datasets.
경제교육과 경제행위의 합리성 : 실험경제학 방법 (2005)

본고에서는 실험경제학의 도구를 이용하여 경제교육이 각 개인의 합리적 의사결정에 미치는 영향을 분석하였다. 이를 위해 우선 실험경제학의 매몰비용실험과 무임승차실험을 이용하여 경제교육이 개인적 합리성과 사회적 합리성에 미치는 영향을 고찰하였다. 두 가지 경제실험에서 밝혀진 주요결과는 다음과 같다. 첫째, 매몰비용 회피지수는 개인적 합리성을 판단하는 지표로서 적합하며, 이러한 매몰비용 회피지수는 중등사회과 주전공 교사집단과 부전공 교사집단간에 유의미한 차이가 있다. 둘째, 무임승차지수는 사회적 합리성을 판단하는 지표로서 적합하며, 중등 사회과 교사들의 무임승차지수는 0.54 정도이다. 셋째, 개인적 합리성과 사회적 합리성간에는 음(-)의 상관관계가 존재한다. 넷째, 경제학을 12학점 이상 이수한 집단은 다른 비교집단에 비해 개인적 합리성은 높으나 사회적 합리성은 낮은 것으로 나타났다.
Fucose-specific conjugation of hydrazide derivatives to a vascular-targeting monoclonal antibody in IgG format (2012)

We describe a method that enables specific and efficient conjugation of hydrazide-moieties to an IgG targeting the tumor neovasculature. The resulting chemically defined, homogeneous hydrazone-linked IgG conjugates remain immunoreactive and have a half-life of approximately 18 hours at physiological pH and temperature suitable for localized delivery of toxic drugs.
Smart Nanogels for Biomedical Applications (2020)

Chapter 22 Smart nanogels are one of the most important innovations that have emerged in the field of nanomedicine and biomedical applications. In recent advances in the applications of biomaterials, nanogels have emerged as novel candidates for drug delivery, biosensing, imaging, tissue engineering, and targeted delivery of bioactive compounds. The present chapter gives a basic understanding of the hydrogels and introduces the nanoparticle form of hydrogels known as “Nanogels.” Nanogels have synergistic properties due to their interpenetrating networks as well as nanoscale properties such as small size and high surface-to-volume ratio. These hybrid materials exhibit high drug loading, are capable of crossing strong barriers and are also highly biocompatible. In brief, this chapter describes the basic synthetic methodology and characterization techniques of nanogels. It also discusses the natural and synthetic polymers deployed for the synthesis of nanogels. Moreover, it highlights the important literature reported for the biomedical applications of nanogels.
Silicon modulator based on interleaved capacitors in subwavelength grating waveguides (2016)

Modulators based on free-carrier plasma dispersion effect has attracted a lot of attention in the recent years. Particularly, a lot of effort is dedicated nowadays into optimizing carrier accumulation silicon modulators. In this work a novel structure of carrier accumulation modulator is proposed and analyzed. The structure is based on interleaved capacitors in a periodic segmented waveguide such as SubWavelength Gratings (SWG) waveguides. This new structure overcomes the major limitation of carrier accumulation structures, which is the limited overlap of the optical mode with the region where the carrier accumulation takes place. The analysis of this novel structure is presented in detail from the optical and the electrical point of view. Furthermore, the procedure to analyze and extract the modulator performance is also presented. Values of modulation efficiency and loss below 0.5Vcm and 5 dB respectively were obtained for the proposed modulator.
Studies on Polypeptides. XXIX. Synthetic Peptides Related to the N-Terminus of Bovine Pancreatic Ribonuclease A (Positions 1-7)1-4 (1965)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStudies on Polypeptides. XXIX. Synthetic Peptides Related to the N-Terminus of Bovine Pancreatic Ribonuclease A (Positions 1-7)1-4Klaus Hofmann, Ralph Schmiechen, Robert D. Wells, Yecheskel Wolman, and Noboru YanaiharaCite this: J. Am. Chem. Soc. 1965, 87, 3, 611–619Publication Date (Print):February 1, 1965Publication History Published online1 May 2002Published inissue 1 February 1965https://pubs.acs.org/doi/10.1021/ja01081a039https://doi.org/10.1021/ja01081a039research-articleACS PublicationsRequest reuse permissionsArticle Views195Altmetric-Citations41LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts