gebhart/patrepeval huggingface dataset:
Born Effective Charges and Piezoelectric Coefficients of BiXO3 (2009)

We have calculated the Born effective charges and piezoelectric coefficients of BiXO3 in various crystals by first-principles methods. Results suggest that there is a difference between the tetragonal and the rhombohedral phases in the electric state in BiXO3, and the covalency between the bismuth and surrounding oxygen of the rhombohedral phase is stronger than that of the tetragonal phase. The calculated Born effective charges and piezoelectric coefficients suggest that the covalency between bismuth and oxygen is important for the piezoelectric response in the rhomboherdal phase, but in the tetragonal phase, the covalency between the B-site cation and oxygen is important for the piezoelectric response. In the R3c symmetry, the piezoelectric coefficients are largest, suggesting that the counter rotation of oxygen around the [111] direction in the R3c symmetry is effective for the hybridization between bismuth and oxygen.
Worst Case Analysis of Age of Information in a Shared-Access Channel (2019)

Freshness of status update packets is essential for enabling a wide range of Internet of Things (IoT) applications. In this paper, we consider a status update system in which various sensors are assigned to transmit status update packets of a physical process to a desired destination. We consider that the sensors share a wireless channel and contend for the channel access based on a carrier sense multiple access (CSMA) method. We study freshness of the status update system at the destination using the age of information (AoI) metric. To this end, we analyze the worst case average AoI for each sensor in the CSMA-based system. Numerical results show that the AoI in the CSMA-based system may dramatically increase when the number of sensors increases. Moreover, we observe that the contention window size and the packet arrival rate must be optimized since they have a critical role in the performance of the system.
Effects of Electrical Stimulation in Tinnitus Patients: Conventional Versus High-Definition tDCS (2018)

TDCS and HD tDCS resulted in a clinically significant improvement in TFI in 32% of the patients, with the 3 stimulation positions having similar results. Future research should focus on long-term effects of electrical stimulation.
Upper limb EMG artifact rejection in motor sensitive BCIs (2010)

Motor imagery-based brain computer interface (BCI) technologh has mototor rehabilitation as one of its main fields of application. The use of a BCI as a neuroprosthetic for paralyzed limb motor restoration implies normally absence of muscle activity. It is still an open question whether residual motor activity in healthy individuals or in patients causes a bias in the modulation of a motor imagery-based BCI control signal. Although the influence of electromyographical (EMG) activity in necka nd cranial muscles upon BCI has been studied, not much has been said concerning the revelance of EMG activity arising from arm muscles. We therefore used a hand motor imagery-based BCI system paradigm designed for motor rehabilitation coupling a BCI with an online driven robotic orthosis to compare different EMG activity detection methods regarding their influence in the resulting analysis of neurophysiological signals. Fourteen healthy subjects underwent four sessions in which they were asked to perform motor imagery task alone (receiving no feedback), motor imagery with (visual and proprioceptive)feedback, active movement, passive movement and rest. Six different EMG feature extraction methods were calculated and three different data time windows were used for muscle activity threshold definition. Three different electrode spatial distributions were utilized for removing the EMG artifacts: a) coming from all the electrodes on the arms, b) just the ones placed on the imagery side and c) just the ones on the healthy arm. We compared the different EMG rejection methods by calculating the number of trials deemed artifact-free by each method. In this paper we demonstrate that different EMG artifact removal methods lead to distinct partitions of the total available data, thus yielding different influence of the method used to remove EMG artifacts on task related artifacts regarding number of trials contaminated and the differences in trials rejected using the different methods.
Natural and Synthetic Huperzine A: Effect on Cholinergic Function in Vitro and in Vivoa (1993)

Huperzine A has been shown to be useful in the treatment of symptoms of dementia of the Alzheimer type. Our initial attempts to synthesize (-)Huperzine A resulted in the racemic mixture of (+/-)Huperzine A. We have therefore compared the in vitro and in vivo effects of (+/-)Huperzine A with those of (-)Huperzine A in rats. The results indicate a similar biological mechanism of action between the two, but that the racemic mixture of (+/-)Huperzine A has a weaker biological activity than the natural product (-)Huperzine A, presumably due to the presence in the mixture of (+)Huperzine A, which is considerably less potent than the (-)isomer.
Heritability and genetic variance estimation of Osteosarcoma (OSA) in Irish Wolfhound, using deep pedigree information (2021)

The results of this study indicate that OSA in the Irish Wolfhound is highly heritable, and support the need for future research investigating associated genetic mutations.
A Kinetic Model for the Action of the Inorganic Pyrophosphatase from Bakers' Yeast. The Activating Influence of Magnesium Ions (1972)

A systematic analysis of the kinetics of the crystallized inorganic pyrophosphatase from bakers' yeast is presented. The complications arising from the existence of various complexes between magnesium and pyrophosphate are obviated to a large extent by choosing the free metal Mg2+ and the 1:1 complex of magnesium and pyrophosphate as the concentration variables. Out of a great number of possible kinetic models the one best fitting the experimental data was selected by computer model fitting. It is an equilibrium model in which magnesium acts as an activator and the 1:1 complex of magnesium and pyrophosphate is the substrate. It has been shown that from the two possible species of the 1:1 complex at pH 7.2 either the unprotonated form is the true substrate or the unprotonated and protonated forms together are alternative substrates. Spectroscopic binding studies support the conclusions drawn from the kinetics.
Circulating 25‐hydroxyvitamin D, vitamin D binding protein and risk of advanced and lethal prostate cancer (2018)

We previously found that higher total 25-hydroxyvitamin D [25(OH)D] levels were associated with lower risk of lethal prostate cancer. However, the relationships of bioavailable 25(OH)D and vitamin D binding protein (VDBP) with risk of advanced and lethal prostate cancer are unclear. In a prospective case-control study of 156 pairs of advanced prostate cancer cases and controls, we directly measured prediagnostic circulating 25(OH)D and VDBP and calculated bioavailable 25(OH)D using a validated formula. We examined the association of bioavailable 25(OH)D and VDBP levels with risk of advanced and lethal prostate cancer and whether total 25(OH)D levels interacted with VDBP levels to affect the risk. Conditional logistic models were used to calculate odds ratios (ORs) and 95% confidence intervals (CIs). Compared to total 25(OH)D (p<sub>trend</sub> = 0.02), bioavailable 25(OH)D levels were not more strongly associated with risk of advanced prostate cancer (p<sub>trend</sub> = 0.14). Although VDBP levels were not associated with risk of advanced prostate cancer (p<sub>trend</sub> = 0.16), we observed an interaction between total 25(OH)D levels and VDBP levels in relation to risk of advanced prostate cancer (p<sub>interaction</sub> = 0.03). Compared to those with total 25(OH)D levels below the median and VDBP levels above the median (at highest risk), men with both levels above the median had a multivariable-adjusted OR of 0.31 (95% CI, 0.15-0.65) for advanced prostate cancer. We observed similar results when we restricted the analyses to 116 lethal prostate cancer cases and their controls. Our data suggest that VDBP levels may modify the association between total 25(OH)D levels and risk of advanced and lethal prostate cancer.
Multicell High-Temperature High-Shear Capillary Viscometer (1986)

A commercial High-Temperature High-Shear Capillary Viscometer (HTHS) has been designed and developed to meet the needs of the anticipated HTHS specification which may be included in the SAE Viscosity Classification J300 for engine oils. It is intended specifically for measuring the viscosity of engine oils. The viscometer can be used for other temperatures and shear rates and for liquids other than engine oils.
Alpha Particles Play a Relatively Minor Role in Magnetized Target Fusion Systems (2002)

Two problems related to alpha particle physics in magnetized target fusion (MTF) systems are briefly discussed. First, we evaluate the pressure and density of alpha particles under the assumption that they are perfectly confined and have a classical slowing-down distribution. It turns out that because of a comparatively low plasma temperature in MTF systems, the relative pressure and density of alpha particles are more than an order of magnitude less than in fusion reactors based on ITER-type tokamaks. Therefore, one may expect that even in the extreme case of a perfect confinement of alpha particles, their presence will have a much weaker (than in the case of tokamaks) effect on plasma stability and transport. Second, we discuss the kinetics of plasma burn under the opposite extreme assumption that all the alpha particles are instantaneously lost, without leaving any energy in a plasma. It turns out that even in this case, the plasma energy yield in batch-burn systems is only weakly affected by burnout effects.
Chiral Recognition of D‐Kyotorphin by Lipidic Membranes: Relevance Toward Improved Analgesic Efficiency (2006)

D-Kyotorphin (D-KTP), the most potent isomer of the endorphin-like dipeptide kyotorphin (KTP), is a good drug candidate for the treatment of chronic pain and is thought to be involved in receptor-mediated processes. According to the "membrane catalysis" model, ligands interact with membrane lipids to attain high local concentrations in the receptor vicinity and to adopt the necessary conformation for docking. Therefore, the interaction and recognition of D-KTP by membranes is potentially important to its increased analgesic effect. In spite of the neutral net charge of D-KTP at pH 7.4, fluorescence spectroscopy reveals that the interaction with large unilamellar vesicles is more extensive than was observed for KTP. The tyrosine residue interacts extensively with rigid membranes, with a location and well-defined orientation in the bilayer. This suggests not only that D-KTP meets the structural constraints needed for receptor-ligand interaction in a manner similar to that of KTP, but also that the stronger membrane interaction and ability to discriminate rigid membrane domains might contribute to its improved analgesic effect.
A Novel Open‐Loop Tracking Strategy for Photovoltaic Systems (2013)

This paper approaches a dual-axis equatorial tracking system that is used to increase the photovoltaic efficiency by maximizing the degree of use of the solar radiation. The innovative aspect in the solar tracker design consists in considering the tracking mechanism as a perturbation for the DC motors. The goal is to control the DC motors, which are perturbed with the motor torques whose computation is based on the dynamic model of the mechanical structure on which external forces act. The daily and elevation angles of the PV module represent the input parameters in the mechanical device, while the outputs transmitted to the controller are the motor torques. The controller tuning is approached by a parametric optimization process, using design of experiments and response surface methodology techniques, in a multiple regression. The simulation and experimental results demonstrate the operational performance of the tracking system.
Rate Constants for the Gas-Phase Reactions of OH Radicals with a Series of C6−C14Alkenes at 299 ± 2 K (2009)

Rate constants for the gas-phase reactions of OH radicals with the C(6)-C(14) 2-methyl-1-alkenes and the C(6)-C(10) trans-2-alkenes have been measured at 299 +/- 2 K and atmospheric pressure of air using a relative rate technique. The rate constants obtained (in units of 10(-11) cm(3) molecule(-1) s(-1)) were as follows: 2-methyl-1-pentene, 5.67 +/- 0.21; 2-methyl-1-hexene, 6.50 +/- 0.11; 2-methyl-1-heptene, 6.71 +/- 0.21; 2-methyl-1-octene, 7.02 +/- 0.16; 2-methyl-1-nonene, 7.28 +/- 0.21; 2-methyl-1-decene, 7.85 +/- 0.26; 2-methyl-1-undecene, 7.85 +/- 0.21; 2-methyl-1-dodecene, 7.96 +/- 0.26; 2-methyl-1-tridecene, 8.06 +/- 0.37; trans-2-hexene, 6.08 +/- 0.26; trans-2-heptene, 6.76 +/- 0.32; trans-2-octene, 7.23 +/- 0.21; trans-2-nonene, 7.54 +/- 0.16; and trans-2-decene, 7.80 +/- 0.26, where the indicated errors are two least-squares standard deviations and do not include the uncertainty associated with the rate constant for the reference compound alpha-pinene. Our data show that the rate constants for the reactions of OH radicals with 2-methyl-1-alkenes and trans-2-alkenes increase with increasing carbon number, suggesting that this is in part due to H-atom abstraction from the C-H bonds of the alkyl substituent groups. Combined with previous literature data for the reactions of OH radicals with a series of 1-alkenes, we propose that the increase in rate constant with increasing carbon number is due to H-atom abstraction from the C-H bonds of the alkyl substituent groups and to enhancement of the rate constant for OH radical addition to the C=C bond, which increases with carbon number of a C(n)-alkyl substituent group up to a maximum at approximately C(8).
Vascular endothelial growth factor (VEGF) expression is a prognostic factor for radiotherapy outcome in advanced carcinoma of the cervix (2000)

The aim of the study was to evaluate VEGF expression in tumour biopsies as a prognostic factor for radiotherapy outcome in advanced carcinoma of the cervix. A retrospective study was carried out on 100 patients. Pre-treatment tumour VEGF expression was examined immunohistochemically in formalin-fixed, paraffin-embedded biopsies using a widely available commercial antibody. A semi-quantitative analysis was made using a scoring system of 0, 1, 2, and 3, for increasing intensity of staining. High VEGF expression was associated with a poor prognosis. A univariate log rank analysis found a significant relationship with overall survival (P = 0.0008) and metastasis-free survival (P = 0.0062), but not local control (P = 0.23). There was no correlation between VEGF expression and disease stage, tumour differentiation, patient age, or tumour radiosensitivity (SF2). In a Cox multivariate analysis of survival VEGF expression was the most significant independent prognostic factor (P = 0.001). After allowing for VEGF only SF2 was a significant prognostic factor (P = 0.003). In conclusion, immunohistochemical analysis of VEGF expression is a highly significant and independent prognostic indicator of overall and metastasis-free survival for patients treated with radiotherapy for advanced carcinoma of the cervix. It is also a rapid and easy method that could be used in the clinical setting, to identify patients at high risk of failure with conventional radiotherapy who may benefit from novel approaches or chemoradiotherapy.
When is a global health program global? (2014)

Editors' Note: Dr. Chin and authors Aarli and Abramsky discuss the lack of resources but surplus of enthusiasm with regard to neurology education in sub-Saharan Africa. Dr. Chow, an anesthesiologist, referencing “Education Research: Changing practice: Residents' adoption of the atraumatic lumbar puncture needle,” discusses his own educational initiative in teaching …
Supplementary Figure 3 from TGF-β Receptor II Loss Promotes Mammary Carcinoma Progression by Th17-Dependent Mechanisms (2023)

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ChemInform Abstract: Novel Diphosphite Derived from D‐gluco‐Furanose Provides High Regio‐ and Enantioselectivity in Rh‐Catalyzed Hydroformylation of Vinyl Arenes. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Stepwise method based on Wiener estimation for spectral reconstruction in spectroscopic Raman imaging (2017)

Raman spectroscopy has demonstrated great potential in biomedical applications. However, spectroscopic Raman imaging is limited in the investigation of fast changing phenomena because of slow data acquisition. Our previous studies have indicated that spectroscopic Raman imaging can be significantly sped up using the approach of narrow-band imaging followed by spectral reconstruction. A multi-channel system was built to demonstrate the feasibility of fast wide-field spectroscopic Raman imaging using the approach of simultaneous narrow-band image acquisition followed by spectral reconstruction based on Wiener estimation in phantoms. To further improve the accuracy of reconstructed Raman spectra, we propose a stepwise spectral reconstruction method in this study, which can be combined with the earlier developed sequential weighted Wiener estimation to improve spectral reconstruction accuracy. The stepwise spectral reconstruction method first reconstructs the fluorescence background spectrum from narrow-band measurements and then the pure Raman narrow-band measurements can be estimated by subtracting the estimated fluorescence background from the overall narrow-band measurements. Thereafter, the pure Raman spectrum can be reconstructed from the estimated pure Raman narrow-band measurements. The result indicates that the stepwise spectral reconstruction method can improve spectral reconstruction accuracy significantly when combined with sequential weighted Wiener estimation, compared with the traditional Wiener estimation. In addition, qualitatively accurate cell Raman spectra were successfully reconstructed using the stepwise spectral reconstruction method from the narrow-band measurements acquired by a four-channel wide-field Raman spectroscopic imaging system. This method can potentially facilitate the adoption of spectroscopic Raman imaging to the investigation of fast changing phenomena.
Tratamento cirúrgico da comunicação interventricular e rotura da parede livre do ventrículo esquerdo após infarto agudo do miocárdio e da disjunção atrioventricular após troca da valva mitral, empregando o dispositivo de isolamento ventricular (DIV):: estudo experimental (1997)

A rotura de parede livre do ventrículo esquerdo (VE) e a comunicação interventricular (CIV) por rotura de septo são dois eventos catastróficos que podem complicar a evolução do infarto agudo do miocárdio (IAM). A oportunidade do tratamento cirúrgico, o acesso à CIV e a técnica cirúrgica ideal para o tratamento desta complicação são muito discutidos na literatura (1-5). Os resultados, porém, são quase unânimes: alta taxa de mortalidade. A rotura da parede posterior do ventrículo esquerdo pós troca da valva mitral (disjunção atrioventricular) não é uma complicação rara, sendo quase sempre fatal (6, 7). O objetivo de nosso trabalho é discutir a alternativa de tratamento cirúrgico destas graves lesões, sem o manuseio direto do músculo cardíaco friável, necrozado. Desenvolvemos e testamos em animais (carneiros) o dispositivo de isolamento ventricular (DIV). No período de 12/7/95 a 10/1/96, operamos 12 carneiros adultos para o implante do DIV. No primeiro período de aprendizado da técnica de implante e de desenvolvimento da prótese, operamos 7 animais, sem sucesso. No segundo período operamos 5 animais, já com o DIV completamente desenvolvido e com a técnica cirúrgica já padronizada; obtivemos sucesso com todos os animais, sobrevivendo com bom débito cardíaco, constatado ao ecocardiograma e à ventriculografia. Após 20 dias de sobrevida, os animais foram submetidos a ventriculografia e ecocardiografia. Observamos o completo isolamento da cavidade ventricular com o emprego do DIV, obtendo o tratamento provisório destas graves lesões.
Vorlesung Materialflusslehre am 17.01.2012, Teil 1 (2012)

Vorlesung Materialflusslehre im Wintersemester 2011/2012
Integrated Passive Devices and Switching Circuit Design for a 3D DC/DC Converter up to 60 V (2019)

This work presents the design and test of a switched-cap 3D DC/DC converter able to work up to 60[Formula: see text]V. The switches and the control circuits are integrated single-chip in a high-voltage (HV) MOS technology, and the passive devices are stacked on top of the chip. As an innovation versus the state-of-the-art, the work first presents the design of integrated passive devices, based on through silicon vias (TSV) MOS-compatible technology, which are suitable for switching converter applications up to 60[Formula: see text]V. Then, the implementation and experimental characterization of the switched-cap 3D DC/DC is proposed, with the silicon TSV capacitors stacked on top of the 0.35[Formula: see text][Formula: see text]m HV-MOS die. Compared with the state-of-the-art, the proposed 3D DC/DC converter is a compact circuit, able to directly regulate a wide input voltage range (from 6[Formula: see text]V to 60[Formula: see text]V) to a 5[Formula: see text]V, 2[Formula: see text]W output. Hence, it is suitable to supply low-power loads, such as control units and/or sensors, directly from the 48[Formula: see text]V power line available in hybrid vehicles or telecom and networking systems.