gebhart/patrepeval huggingface dataset:
Flight planning for stereo radar mapping (1975)

The configuration of La ions of La(2)@C(80) in the [80]fullerene cage was investigated by use of quantum chemical calculations. We found that the D(3)(d)() configuration is the global minimum in total energy, being more stable by 1.9 kcal/mol than the D(2)(h)() configuration, which has been considered to be the most stable. The potential energy surface calculation clarified that La ions travel between 10 equivalent D(3)(d)() positions through D(2)(h)() positions and consequently form pentagonal dodecahedral trajectory, which is in good agreement with the previous synchrotron radiation structural study. The experimental and theoretical investigation of the Raman spectrum revealed that the symmetry of molecular vibration is dramatically reduced simply by encapsulation of two La ions, and resulting vibrational modes were successfully assigned. The Raman peak at 163 cm(-)(1) was interpreted as the in-phase synchronously coupled mode of the [80]fullerene cage elongation and the La-La stretching, rather than a conventional and naive assignment as a metal-to-cage vibration mode.
Survival Analysis of Irish Amyotrophic Lateral Sclerosis Patients Diagnosed from 1995–2010 (2013)

Our analysis explored the strengths and weaknesses of Cox proportional hazard and Royston-Parmar flexible parametric methods. By including time varying components we were able to gain deeper understanding of the dataset. Variation in survival between time periods appears to be due to missing data in the first time period. The use of age as timescale to account for confounding by age resolved breaches of the proportional hazards assumption, but in doing so may have obscured deficiencies in the data. Our study demonstrates the need to test for, and fully explore, breaches of the Cox proportional hazards assumption. Royston-Parmar flexible parametric modeling proved a powerful method for achieving this.
β-m-Hydroxyphenylserine and β-p-Hydroxyphenylserine1 (1953)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTβ-m-Hydroxyphenylserine and β-p-Hydroxyphenylserine1William A. BolhoferCite this: J. Am. Chem. Soc. 1953, 75, 18, 4469–4473Publication Date (Print):September 1, 1953Publication History Published online1 May 2002Published inissue 1 September 1953https://pubs.acs.org/doi/10.1021/ja01114a022https://doi.org/10.1021/ja01114a022research-articleACS PublicationsRequest reuse permissionsArticle Views246Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Multifunctional Au-ZnO Plasmonic Nanostructures for Enhanced UV Photodetector and Room Temperature NO Sensing Devices (2014)

In this study we report the enhancement of UV photodetection and wavelength tunable light induced NO gas sensing at room temperature using Au-ZnO nanocomposites synthesized by a simple photochemical process. Plasmonic Au-ZnO nanostructures with a size less than the incident wavelength have been found to exhibit a localized surface plasmon resonance (LSPR) that leads to a strong absorption, scattering and local field enhancement. The photoresponse of Au-ZnO nanocomposite can be effectively enhanced by 80 times at 335 nm over control ZnO. We also demonstrated Au-ZnO nanocomposite's application to wavelength tunable gas sensor operating at room temperature. The sensing response of Au-ZnO nancomposite is enhanced both in UV and visible region, as compared to control ZnO. The sensitivity is observed to be higher in the visible region due to the LSPR effect of Au NPs. The selectivity is found to be higher for NO gas over CO and some other volatile organic compounds (VOCs), with a minimum detection limit of 0.1 ppb for Au-ZnO sensor at 335 nm.
Rectal biopsy as an aid to cancer control in ulcerative colitis. (1967)

EDITORIAL COMMENT This is a very important paper as it provides the clinician with a new method of identifying patients with total colitis who may be particularly exposed to the risk of carcinoma. Rectal biopsies of flat mucosa may demonstrate a certain cellular pattern which has been shown to be particularly associated with carcinoma.
Expansion joints subjected to extreme movement conditions - the particular challenges (2007)

&lt;p&gt;The paper gives a brief introduction into the world of large bridge expansion joints, their special needs and the particular challenges they present.&lt;/p&gt; &lt;p&gt;A special focus is given to the experience gained when designing, manufacturing, shipping and installing modular expansion joints for the Run Yang Bridge, China’s largest and the world’s third largest suspension bridge. With its 27 cells, the larger of the bridge’s modular expansion joints facilitates longitudinal movement of 2,160mm, at the time the largest ever installed, anywhere in the world.&lt;/p&gt;
海蛇舞动，海浪显“能” (2009)

从远处看，它们只不过像海平面上细细的红线，很容易隐没在波涛汹涌的大西洋碧浪中。但走近些看这些漂浮在葡萄牙近海由一家英国公司历时10年时间制造的140米长的管子，其重要性就显而易见了。它们是探求清洁能源全新领域的开始。
Long-term estimates of ambient air pollution and perturbations in the peripheral blood transcriptome in a large Dutch twin cohort (2020)

Background/Aim Studying the internal exposome has the potential to provide insight into the biological pathways through which air pollutants affects disease risk. In this study we linked long-term estimates for seven air pollutants and their elemental composition to transcriptomics data collected in the Dutch Twin Register (NTR) cohort. In addition to standard regression techniques we exploited the twin design by comparing gene expression among pairs of monozygotic and dizygotic twins. Replication of findings will be conducted in the Dutch NESDA cohort. Methods In both discovery (NTR, n= 2438) and replication (NESDA, n= 2341) cohorts, long-term land use regression model estimates were generated for nitrogen oxides (NO2, NOx), particulate matter (PM2.5 (including elemental composition), PM2.5abs, PM10, PMcoarse), and ultrafine particles (UFP). Other covariates were assessed using geospatial methods or questionnaires. Gene expression was assessed using Affymatrix U219 arrays (n=44,241 probes). Multi-variable univariate mixed-effect models were used to assess the association between these air pollutants and the transcriptome. Functional analysis was conducted using DAVID (v6.8). Results In the NTR cohort long-term exposure to PM2.5 (and few of the other pollutants) was associated with 374 transcripts (Benjamini- Hochberg p&lt;0.05). Elemental Copper and Sulphur in PM2.5 significantly contributed to this signal. Associations were stronger among residents of less urban areas, with lower exposure levels, and weaker among men. Results were robust in a series of sensitivity analyses. Genes most significantly differentially expressed were ZNF791, BTBD1 and OSBPL8 (upregulated), and WIPF2 (downregulated). We observed strong evidence for enrichment of phosphoprotein and alternative splicing pathways. Twin-only models did not yield strong associations. Replication analyses in the NESDA cohort are ongoing. Conclusions Results from our analyses in the NTR cohort suggest a distinct PM2.5 signal in the peripheral blood transcriptome, primarily occurring in phosphoprotein and alternative splicing pathways.
Comparative evaluation of surface deposits on high water content hydrogel contact lens polymers. (1990)

Twenty soft contact lens wearers were fit with a high water content, non-HEMA (ofilcon A) lens (Durasoft 4; Wesley-Jessen) on the test eye. Patients subsequently wore one of the following four lenses on the same eye: a high-water content non-HEMA (surfilcon A) lens (Permaflex 74; CooperVision); a modified mid-water content HEMA (bufilcon A) lens (Hydrocurve Elite; Sola/Barnes-Hind); a low-water content HEMA (polymacon) lens (O4; Bausch & Lomb); or a low-water content non-HEMA (crofilcon A) lens (CSI; Sola/Barnes-Hind). All lenses were worn on a daily wear basis for one month and then evaluated with the scanning electron microscope (SEM). The amount of surface deposition was measured in terms of the area of lens covered by deposit as visualized on a standard series of SEM photographs. When control was obtained for patient, eye, technique, care system, and wearing time, similar amounts of deposit were found on the two high water content soft lenses. A significantly greater amount of deposit was found on the non-HEMA high water content ofilcon A lens compared to the mid-water content modified HEMA material. However, when the patient's tendency to produce "heavy" or "light" deposits on a soft lens surface is taken into account, then for the lighter depositors the high water content non-HEMA material was found to be as acceptable as the low water content HEMA and non-HEMA materials. But for heavy depositors the high water content non-HEMA material is not recommended.
Personalizable edge services for web accessibility (2006)

Web Content Accessibility guidelines by W3C [29] provide several suggestions for Web designers on how to author Web pages in order to make them accessible to everyone. In this context, we are proposing the use of edge services as an efficient and general solution to promote accessibility and breaking down the digital barriers that inhibit users with disabilities to actively participate to any aspect of our society.To this aim, we present in this paper PAN: Personalizable Accessible Navigation, that is a set of edge services designed to improve Web pages accessibility, developed and deployed on top of a programmable intermediary framework [8].The characteristics and the location of the services, i. e. provided by intermediaries, as well as the personalization and the opportunities to select multiple profiles make PAN a platform that is especially suitable in accessing the Web seamlessly also from mobile terminals.
Camera calibration and orientation for PCB jet printing inspection (2020)

Abstract To assess the quality of printed solder joints in the jet printing of printed circuit boards, a calibrated camera is used to reconstruct the solder volume via photogrammetry as a specific task of computer vision. This requires a procedure for calibration and orientation determination due to restrictions within the image acquisition process. We herein consider a novel application area called an ultra-close range normal case photogrammetry , where a camera acquires small objects at small operating distances and fields of depth. Because the camera cannot rotate or translate in the z-direction, we propose and evaluate four calibration procedures in terms of their capability in a normal case calibration within the ultra-close range. To set up an optimal calibration pipeline, a three-dimensional (3D) calibration field is used for single and multi-image calibrations. To enhance the accuracy and to simplify the assignment of 3D coordinates to the detected markers, we propose a geometry-based estimation of the lens model to undistort the image points. Close-range applications utilize spacer rings and extension tubes to enlarge the magnification and reduce the operating distance. We also examine the influence of these extensions on the intrinsics of the camera and the reconstruction result. Additionally, we demonstrate the dependence of the accuracy on the lens model in terms of radial and tangential distortions and the number of distortion coefficients regarding the reprojection error $$\epsilon _{repro}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msub> <mml:mi>ϵ</mml:mi> <mml:mrow> <mml:mi>repro</mml:mi> </mml:mrow> </mml:msub> </mml:math> . Finally, we provide recommendations for a lens configuration for ultra-close range normal case calibrations and measurements, based on the calibration and reconstruction results, which are evaluated by the 2D reprojection error $$\epsilon _{repro}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msub> <mml:mi>ϵ</mml:mi> <mml:mrow> <mml:mi>repro</mml:mi> </mml:mrow> </mml:msub> </mml:math> and the 3D reconstruction error $$\epsilon _{recon}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msub> <mml:mi>ϵ</mml:mi> <mml:mrow> <mml:mi>recon</mml:mi> </mml:mrow> </mml:msub> </mml:math> obtained from a second independent calibration field.
Nitric Oxide–Releasing Aspirin Derivative, NCX 4016, Promotes Reparative Angiogenesis and Prevents Apoptosis and Oxidative Stress in a Mouse Model of Peripheral Ischemia (2004)

Pretreatment with the new oral NO-releasing aspirin derivative stimulates reparative angiogenesis and prevents apoptosis and oxidative stress, thereby alleviating the consequences of supervening arterial occlusion.
Peripheral blood progenitor cell collections in multiple myeloma: predictors and management of inadequate collections (1996)

Thirty-seven patients with previously treated multiple myeloma (MM) underwent peripheral blood progenitor cell (PBPC) collection following high-dose cyclophosphamide and GM-CSF or sequential IL-3 and GM-CSF. Patients with an inadequate collection were considered for a second or third collection. 25 patients underwent subsequent autotransplant. The only variable predictive of CFU-GM yield was the extent of prior melphalan therapy. All repeat collections were unsuccessful and patients infused with an autograft obtained from multiple sets of collections had a high incidence of delayed engraftment. We conclude that melphalan should be avoided or PBPC collection performed early in the disease course in patients who are potential transplant candidates.
High-conversion-efficiency widely-tunable all-fiber optical parametric oscillator (2007)

A high-conversion-efficiency widely-tunable all-fiber optical parametric oscillator is described. It is based on modulation instability in the normal dispersion regime near the fiber's zero-dispersion wavelength. A 40 m long dispersion-shifted fiber is used in a synchronously pumped ring cavity. We demonstrate continuous sideband tuning from 1300 to 1500 nm and 1600 to 1860 nm by tuning the pump wavelength between 1532 and 1556 nm. Internal conversion efficiencies of up to 40% are achieved.
Chapitre second. L'industrialisation régionale dans les années 1950 - 1964 (1980)

A) - Contrastes et déséquilibres inter-régionaux 1) - Pour répondre aux besoins d'une population en augmentation rapide et pour rétablir l'équilibre financier extérieur, il est nécessaire de créer des emplois et d'accroître la production des biens exportables. Après 1945, l'industrialisation du pays est l'un des objectifs prioritaires de la politique économique des pouvoirs publics. Cependant, le développement de l'industrie ne constitue pas seulement un problème de nature macro-économique et...
Boronate Probes as Diagnostic Tools for Real Time Monitoring of Peroxynitrite and Hydroperoxides (2012)

Boronates, a group of organic compounds, are emerging as one of the most effective probes for detecting and quantifying peroxynitrite, hypochlorous acid, and hydrogen peroxide. Boronates react with peroxynitrite nearly a million times faster than with hydrogen peroxide. Boronate-containing fluorogenic compounds have been used to monitor real time generation of peroxynitrite in cells and for imaging hydrogen peroxide in living animals. This perspective highlights potential applications of boronates and other fluorescent probes to high-throughput analyses of peroxynitrite and hydroperoxides in toxicological studies.
Turbulence Effects in Tilting Pad Journal Bearings: A Review (2022)

This paper reviews the current knowledge on turbulence effects in tilting pad journal bearings. Turbulence is becoming increasingly important in the design of hydrodynamic bearings due to the trend to increase power density in turbomachines and consequently the operating speeds of the hydrodynamic bearings. Turbulence has a series of effects on the bearing performance which may be beneficial or detrimental, depending on the operating conditions. The main turbulence models are recalled and a historical overview on the evolution of numerical simulations of turbulent flow in tilting pad journal bearings is presented. The two broad simulation strategies used are the generalized Reynolds equation and computational fluid dynamics. The main experimental works are then reviewed, and a unified comparison of these works is provided. Novel results on the critical Reynolds number in a tilting pad journal bearing are reported. Much emphasis is given on the experimental evidence for laminar-to-turbulent transition. The evidence used in the literature is reviewed and its reliability is discussed. Lastly, some future research directions are suggested.
Texture synthesis for 3D shape representation (2003)

Considerable evidence suggests that a viewer's perception of the 3D shape of a polygonally-defined object can be significantly affected (either masked or enhanced) by the presence of a surface texture pattern. However, investigations into the specific mechanisms of texture's effect on shape perception are still ongoing and the question of how to design and apply a texture pattern to a surface in order to best facilitate shape perception remains open. Recently, we have suggested that, for anisotropic texture patterns, the accuracy of shape judgments may be significantly affected by the orientation of the surface texture pattern anisotropy with respect to the principal directions of curvature over the surface. However, it has been difficult, until this time, to conduct controlled studies specifically investigating the effect of texture orientation on shape perception because there has been no simple and reliable method for texturing an arbitrary doubly curved surface with a specified input pattern such that the dominant orientation of the pattern everywhere follows a predefined directional vector field over the surface, while seams and projective distortion of the pattern are avoided. In this paper, we present a straightforward and highly efficient method for achieving such a texture and describe how it can potentially be used to enhance shape representation. Specifically, we describe a novel, efficient, automatic algorithm for seamlessly synthesizing, from a sample 2D pattern, a high resolution fitted surface texture in which the dominant orientation of the pattern locally follows a specified vector field over the surface at a per-pixel level and in which seams, projective distortion, and repetition artifacts in the texture pattern are nearly completely avoided. We demonstrate the robustness of our method with a variety of texture swatches applied to standard graphics data sets and we explain how our method can be used to facilitate research in the perception of shape from texture.
Rapid Screening for 31 Mutations and Polymorphisms in the Cystic Fibrosis Transmembrane Conductance Regulator Gene by Luminex® xMAP™ Suspension Array (2005)

A suspension array hybridization assay is described for the detection of 31 mutations and polymorphisms in the cystic fibrosis transmembrane conductance regulator (CFTR) gene using Luminex xMAP technology. The Luminex xMAP system allows simultaneous detection of up to 100 different targets in a single multiplexed reaction. Included in the method are the procedures for design of oligonucleotide capture probes and PCR amplification primers, coupling oligonucleotide capture probes to carboxylated microspheres, hybridization of coupled microspheres to oligonucleotide targets, production of targets from DNA samples by multiplexed PCR amplification, and detection of PCR-amplified targets by direct hybridization to probe-coupled microspheres. Mutation screening with the system is rapid, requires relatively few sample manipulations, and provides adequate resolution to reliably genotype the 25 CFTR mutations and 6 CFTR polymorphisms contained in the ACMG/ACOG/NIH-recommended core mutation panel for general population CF carrier screening.
Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. (1986)

We have examined the incidence and size of infarction after occlusion of different portions of the rat middle cerebral artery (MCA) in order to define the reliability and predictability of this model of brain ischemia. We developed a neurologic examination and have correlated changes in neurologic status with the size and location of areas of infarction. The MCA was surgically occluded at different sites in six groups of normal rats. After 24 hr, rats were evaluated for the extent of neurologic deficits and graded as having severe, moderate, or no deficit using a new examination developed for this model. After rats were sacrificed the incidence of infarction was determined at histologic examination. In a subset of rats, the size of the area of infarction was measured as a percent of the area of a standard coronal section. Focal (1-2 mm) occlusion of the MCA at its origin, at the olfactory tract, or lateral to the inferior cerebral vein produced infarction in 13%, 67%, and 0% of rats, respectively (N = 38)...
Antiacanthamoebic properties of natural and marketed honey in Pakistan (2016)

Objective: To determine antiacanthamoebic activity of natural and marketed honey samples. Methods: Natural honey samples were collected directly from the bee hive and marketed honey samples were purchased from the local market in Karachi, Pakistan. Both honey samples were tested for their flavonoid content (quercetin equivalent per gram of the extract) and phenolic content (gallic acid equivalent per gram). Furthermore, their antioxidant activity was determined by measuring 2,2-diphenyl-1-picrylhydrazyl. Using amoebistatic and amoebicidal assays, the effects of honey samples were tested against growth and viability of Acanthamoeba parasites. Results: Natural honey exhibited potent amoebistatic and amoebicidal effects, in a concentration-dependent manner. Honey-treated Acanthamoeba castellanii showed loss of acanthopodia, following which amoebae detached, rounded up, reduced in size, decreased in cytoplasmic mass and they were observed floating in the culture medium. Importantly, honey-treated amoebae did not revive when inoculated in fresh growth medium, however, glycerol-treated amoebae exhibited viable trophozoite and active growth. In contrast, marketed honey samples varied in their efficacy against Acanthamoeba castellanii. The proportion of flavonoid, as determined by quercetin measurements and the proportion of phenolic, as determined by gallic acid measurements was higher in natural honey compared with marketed honey. Similarly, the antioxidant activity, as determined by 2,2-diphenyl-1-picrylhydrazyl scavenging activity was higher in natural honey vs. marketed honey. Conclusions: This study shows that natural honey has antiacanthamoebic properties and possesses higher flavonoid, phenolic and antioxidant properties compared with the marketed honey. These findings are of concern to the public, health officials, and to the manufacturers regarding production of honey for medical applications.