gebhart/patrepeval huggingface dataset:
Remote Multilinear Compressive Learning With Adaptive Compression (2021)

Multilinear compressive learning (MCL) is an efficient signal acquisition and learning paradigm for multidimensional signals. The level of signal compression affects the detection or classification performance of an MCL model, with higher compression rates often associated with lower inference accuracy. However, higher compression rates are more amenable to a wider range of applications, especially those that require low operating bandwidth and minimal energy consumption such as Internet of Things (IoT) applications. Many communication protocols provide support for adaptive data transmission to maximize the throughput and minimize energy consumption. By developing compressive sensing and learning models that can operate with an adaptive compression rate, we can maximize the informational content throughput of the whole application. In this article, we propose a novel optimization scheme that enables such a feature for MCL models. Our proposal enables the practical implementation of adaptive compressive signal acquisition and inference systems. Experimental results demonstrated that the proposed approach can significantly reduce the amount of computations required during the training phase of remote learning systems but also improve the informational content throughput via adaptive-rate sensing.
Measured dose response in an in vivo rabbit model of ischaemic preconditioning (1998)

Reinhardt, C. P.; Dickson, E. W.; Coakley, S. J.; Renzi, F. P.; Marcel, R.; Becker, R. C. Author Information
Drilling Fluid Density and Hydraulic Drag Reduction With Glass Bubble Additives (2017)

This study concentrates on the use of materials known as hollow glass spheres, also known as glass bubbles, to reduce the drilling fluid density below the base fluid density without introducing a compressible phase to the wellbore. Four types of lightweight glass spheres with different physical properties were tested for their impact on rheological behavior, density reduction effect, survival ratio at elevated pressures, and hydraulic drag reduction effect when mixed with water-based fluids. A Fann75 high pressure high temperature (HPHT) viscometer and a flow loop were used for the experiments. Results show that glass spheres successfully reduce the density of the base drilling fluid while maintaining an average of 0.93 survival ratio, the rheological behavior of the tested fluids at elevated concentrations of glass bubbles is similar to the rheological behavior of conventional drilling fluids and hydraulic drag reduction is present up to certain concentrations. All results were integrated into hydraulics calculations for a wellbore scenario that accounts for the effect of temperature and pressure on rheological properties, as well as the effect of glass bubble concentration on mud temperature distribution along the wellbore. The effect of drag reduction was also considered in the calculations.
Molecular design based on inclusion chemistry. Synthesis, characterization, and crystal structures of a new family of lacunar Schiff base complexes with promise as broad-range host molecules (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMolecular design based on inclusion chemistry. Synthesis, characterization, and crystal structures of a new family of lacunar Schiff base complexes with promise as broad-range host moleculesDorai. Ramprasad, Wang Kan. Lin, Kenneth A. Goldsby, and Daryle H. BuschCite this: J. Am. Chem. Soc. 1988, 110, 5, 1480–1487Publication Date (Print):March 1, 1988Publication History Published online1 May 2002Published inissue 1 March 1988https://pubs.acs.org/doi/10.1021/ja00213a020https://doi.org/10.1021/ja00213a020research-articleACS PublicationsRequest reuse permissionsArticle Views157Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Optics for Engineers (2011)

The field of optics has become central to major developments in medical imaging, remote sensing, communication, micro- and nanofabrication, and consumer technology, among other areas. Applications of optics are now found in products such as laser printers, bar-code scanners, and even mobile phones. There is a growing need for engineers to understan
Outcomes based on age in the phase III METEOR trial of cabozantinib versus everolimus in patients with advanced renal cell carcinoma (2019)

BackgroundCabozantinib improved progression-free survival (PFS), overall survival (OS) and objective response rate (ORR) compared with everolimus in patients with advanced renal cell carcinoma (RCC) after prior antiangiogenic therapy in the phase III METEOR trial (NCT01865747). Limited data are available on the use of targeted therapies in older patients with advanced RCC.MethodsEfficacy and safety in METEOR were retrospectively analysed for three age subgroups: <65 (n = 394), 65–74 (n = 201) and ≥75 years (n = 63).ResultsPFS, OS and ORR were improved with cabozantinib compared with everolimus in all age subgroups. The PFS hazard ratios (HRs) were 0.53 (95% confidence interval [CI]: 0.41–0.68), 0.53 (95% CI: 0.37–0.77) and 0.38 (95% CI: 0.18–0.79) for <65, 65–74 and ≥75 years, respectively, and the OS HRs were 0.72 (95% CI: 0.54–0.95), 0.66 (95% CI: 0.44–0.99) and 0.57 (95% CI: 0.28–1.14). The ORR for cabozantinib versus everolimus was 15% vs 5%, 21% vs 2% and 19% vs 0%, respectively. No significant differences were observed in PFS or OS with age as a categorical or continuous variable. Grade III/IV adverse events (AEs) were generally consistent across subgroups, although fatigue, hypertension and hyponatraemia occurred more frequently in older patients treated with cabozantinib. Dose reductions to manage AEs were more frequent in patients receiving cabozantinib than in those receiving everolimus. Dose reductions and treatment discontinuation due to AEs were more frequent in older patients in both treatment groups.ConclusionsCabozantinib improved PFS, OS and ORR compared with everolimus in previously treated patients with advanced RCC, irrespective of age group, supporting use in all age categories. Proactive dose modification and supportive care may help to mitigate AEs in older patients while maintaining efficacy.
The Wisconsin/GSFC Hale-Bopp Observing Campaign (1997)

From September 1996 to April 1997, we conducted an extensive campaign of observations of several atomic (O, C, H), ionic (H_2O(+) ), and molecular (OH, C_2, C_3, CN, NH_2) emissions from Comet Hale-Bopp, using a variety of telescopes (McMath-Pierce, WHAM, Burrel-Schmidt, WIYN, PBO, WISP), instruments (imagers, Fabry-Perot and grating spectrometers, polarimeters), and data formats (spectra, images, datacubes). We will present an overview of the observations, and highlight early results, some of which will be presented in detail in poster papers at this meeting.
Eine Neuentwicklung der trägerfreien kontinuierlichen Elektrophorese. Zur Trennung hochmolekularer und grobdisperser Teilchen (1964)

Article Eine Neuentwicklung der trägerfreien kontinuierlichen Elektrophorese. Zur Trennung hochmolekularer und grobdisperser Teilchen was published on January 1, 1964 in the journal Biological Chemistry (volume 338, issue Jahresband).
Spatially Resolved Quantum Nano-Optics of Single Photons Using an Electron Microscope (2013)

We report on the experimental demonstration of single-photon state generation and characterization in an electron microscope. In this aim we have used low intensity relativistic (energy between 60 and 100 keV) electrons beams focused in a ca. 1 nm probe to excite diamond nanoparticles. This triggered individual neutral nitrogen-vacancy centers to emit photons which could be gathered and sent to a Hanbury Brown-Twiss intensity interferometer. The detection of a dip in the correlation function at small time delays clearly demonstrates antibunching and thus the creation of nonclassical light states. Specifically, we have also demonstrated single-photon states detection. We unveil the mechanism behind quantum states generation in an electron microscope, and show that it clearly makes cathodoluminescence the nanometer scale analog of photoluminescence. By using an extremely small electron probe size and the ability to monitor its position with subnanometer resolution, we also show the possibility of measuring the quantum character of the emitted beam with deep subwavelength resolution.
Mouse and Human CD1d-Self-Lipid Complexes Are Recognized Differently by Murine Invariant Natural Killer T Cell Receptors (2016)

Invariant natural killer T (iNKT) cells recognize self-lipids presented by CD1d through characteristic TCRs, which mainly consist of the invariant Vα14-Jα18 TCRα chain and Vβ8.2, 7 or 2 TCRβ chains with hypervariable CDR3β sequences in mice. The iNKT cell-CD1d axis is conserved between humans and mice, and human CD1d reactivity of murine iNKT cells have been described. However, the detailed differences between the recognition of human and mouse CD1d bound to various self-lipids by mouse iNKT TCRs are largely unknown. In this study, we generated a de novo murine iNKT TCR repertoire with a wider range of autoreactivity compared with that of naturally occurring peripheral iNKT TCRs. Vβ8.2 mouse iNKT TCRs capable of recognizing the human CD1d-self-lipid tetramer were identified, although such clones were not detectable in the Vβ7 or Vβ2 iNKT TCR repertoire. In line with previously reports, clonotypic Vβ8.2 iNKT TCRs with unique CDR3β loops did not discriminate among lipids presented by mouse CD1d. Unexpectedly, however, these iNKT TCRs showed greater ligand selectivity toward human CD1d presenting the same lipids. Our findings demonstrated that the recognition of mouse and human CD1d-self-lipid complexes by murine iNKT TCRs is not conserved, thereby further elucidating the differences between cognate and cross-species reactivity of self-antigens by mouse iNKT TCRs.
LABORATORY DIAGNOSIS OF RESPIRATORY DISEASES: PCR VERSUS SEROLOGY (2001)

We present a comparison between serology and genetic detection of three bacterial pathogens causing lower respiratory tract infection (LRI). We evaluated serology and PCR for the detection of Mycoplasma pneumoniae, Bordetella pertussis and Chlamydia pneumoniae from 1712 nasopharyngeal and serum samples. For 856 nasopharyngeal samples, average PCR time was 7.2 days, the parallel serum samples was 13 days. Automated extraction of nucleic acids reduces average PCR time to 6.7 days.
Direct semi-blind design of serial linear equalizers for doubly-selective channels (2004)

Recently, serial linear equalizers (SLEs) and serial decision feedback equalizers (SDFEs) have been proposed to mitigate the doubly-selective channel effects. To design the SLE/SDFE and to model the doubly-selective channel, a so-called finite impulse response basis expansion model (FIR-BEM) is used. Initially, the FIR-BEM coefficients of the SLE/SDFE were designed based on the exact knowledge of the FIR-BEM coefficients of the doubly-selective channel. In practice, we can use a direct SLE/SDFE design procedure, which avoids an intermediate channel estimation step. In this paper, we describe this idea for the SLE and focus on direct semi-blind design of the FIR- BEM coefficients of the SLE. Simulation results demonstrate the validity of the proposed approach.
Simple Estimation Method for Life Expectancy of Optical Disks Using Resampling Statistical Analysis (2008)

In this paper, we present and discuss a simple estimation method for the life expectancy of optical disks using resampling (bootstrap) statistical analysis in order to roughly estimate the lifetime of archival-grade disks. The performance of this method was examined experimentally using the Eyring acceleration test with four stress conditions. Results demonstrated the capability of this bootstrap analysis for estimating life expectancy compared with conventional statistical analysis using the Eyring acceleration test.
Dependency-Based Word Embeddings (2014)

While continuous word embeddings are gaining popularity, current models are based solely on linear contexts. In this work, we generalize the skip-gram model with negative sampling introduced by Mikolov et al. to include arbitrary contexts. In particular, we perform experiments with dependency-based contexts, and show that they produce markedly different embeddings. The dependencybased embeddings are less topical and exhibit more functional similarity than the original skip-gram embeddings.
EMPREENDEDORISMO E ENGENHARIA: ESTUDO DE CASO DA DISCIPLINA DE EMPREENDEDORISMO DO CURSO DE ENGENHARIA DE PRODUÇÃO DO ISECENSA (2015)

Dado o historico e vocacao dos Institutos Superiores de Ensino do Centro Educacional Nossa Senhora Auxiliadora (ISECENSA) na educacao, formacao e preparacao de grandes profissionais para o mercado de trabalho e em conformidade com a urgencia de modelos praticos de empreendedorismo no cenario regional, nacional e internacional, bem como da importância do empreendedor como agente economico efetivo e criativo, este trabalho tem por objetivo demonstrar a importância da adocao como disciplina obrigatoria do curso de graduacao em Engenharia de Producao da referida instituicao de uma disciplina especificamente focada no tema acerca do empreendedorismo que tem como nome Topicos III, do empreendedor e do processo de inovacao. Segundo DRUCKER (1998), empreendedorismo e um comportamento e nao um traco da personalidade. Portanto esta pesquisa demonstrara os grandes beneficios e fara um breve relato da instituicao e do tema empreendedorismo e seu ator principal, o empreendedor. Com o intuito de despertar no aluno caracteristicas como criatividade, capacidade de gestao e espirito inovador, tendo como base os conhecimentos obtidos ao longo do curso. Como procedimento metodologico adotado, em funcao dos objetivos, foi concebido como uma pesquisa exploratoria e descritiva. As pesquisas exploratorias, segundo GIL (1995), sao desenvolvidas com objetivo de proporcionar visao geral, de tipo aproximativo, acerca de determinado fato. Portanto, os resultados que se esperam sao as implantacoes de inovacoes tecnologicas por meio de projetos de pesquisa que o ISECENSA oferece ao aluno e os cursos de extensao, proporcionando aos alunos de Engenharia de Producao um diferencial significante na formacao academica, na insercao profissional alem de contribuir positivamente para o desenvolvimento de organizacoes. Palavras Chave: Empreendedorismo, Engenharia de Producao, ISECENSA
Methyl isocyanate inhalation induces tissue factor-dependent activation of coagulation in rats (2018)

Methyl isocyanate (MIC) is a highly toxic industrial chemical causing acute lethality after inhalation. The objective of this study was to determine whether alterations in hemostasis also occur in the immediate hours after exposure. Male rats were exposed to MIC (125-500 ppm) by nose-only vapor inhalation for 30 min. Arterial O<sub>2</sub> saturation was monitored prior to exposure, and hourly thereafter. Rats were euthanized at 1, 2, 4, and 8 hr and plasma analyzed for recalcification clotting time, tissue factor (TF) activity, and protein levels. Hypoxemia, as assessed by pulse oximetry, was an early feature of MIC inhalation. In contrast to sham or low (125 ppm) concentrations, 250 and 500 ppm MIC caused significant declines in blood oxygen saturation (% SpO<sub>2</sub>) at 1 hr, which remained at deficit during the postexposure period. Commensurate with hypoxemia, plasma clotting time was significantly accelerated 1 hr after MIC inhalation (sham treatment: 955 ± 62.8 s; 125 ppm MIC: 790 ± 62 s; 250 ppm: 676 ± 28.0 s; 500 ppm: 581 ± 175 s). This procoagulant effect was transient, with no difference observed between sham and all MIC groups by 8 hr. Similarly, elevated TF activity and protein were detected in plasma 1 hr after MIC inhalation, each of which showed a progressive decline back to control levels at later timepoints. This study demonstrates that MIC inhalation resulted in hypoxemia and transient hypercoagulability of blood. Accelerated clotting occurred rapidly and was likely due to intravascular TF, which initiates the extrinsic coagulation pathway.
Enhanced cerebral bioenergetics with dietary ketosis in Mild Cognitive Impairment (2014)

BACKGROUND: Metabolic disturbance is associated with risk for neurodegeneration, and cerebral glucose hypometabolism is prominent in Alzheimer's disease (AD). Ketone metabolism can compensate for glucose hypometabolism and confers other benefits pert
Analyse de l'écriture manuscrite cursive et caractère bâton (2016)

International audience
Reminiscences on influential papers (2005)

article Share on Reminiscences on influential papers Author: Kenneth A. Ross View Profile Authors Info & Claims ACM SIGMOD RecordVolume 34Issue 3September 2005pp 111–113https://doi.org/10.1145/1084805.1084831Published:01 September 2005Publication History 0citation124DownloadsMetricsTotal Citations0Total Downloads124Last 12 Months1Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
A contractor's viewpoint and recommendations (1974)

Speaking as a contractor specialising in landslide prevention and remedial work, some 50% of the soil movement problems on which we are called upon to carry out remedial works, need never have happened, had the average man in the street sought out and taken advice from people more experienced in soil engineering, or in the building of retaining walls.
Lipoxin A4 and aspirin‐triggered 15‐epi‐LXA4 inhibit tumor necrosis factor‐α‐initiated neutrophil responses and trafficking: novel regulators of a cytokine—chemokine axis relevant to periodontal diseases (1999)

The impact of lipoxin A4 (LXA4) and aspirin-triggered-lipoxins (ATL) was investigated in tumor necrosis factor (TNF alpha)-initiated neutrophil (PMN) responses in vitro and in vivo using LX analogs that are metabolically more stable. At nanomolar levels, the LXA4 and ATL analog 15 R/S-methyl-LXA4 each blocked TNF alpha-stimulated IL-1 beta release by isolated human PMN in vitro. These LXA4-ATL actions were time- and concentration-dependent. The TNF alpha-induced IL-1 beta gene expression was also regulated by 15 R/S-methyl-LXA4. In addition, 15 R/S-methyl-LXA4 added to murine air pouches dramatically inhibited TNF alpha-stimulated leukocyte trafficking in vivo, as well as altered the appearance of both macrophage inflammatory peptide-2 and IL-1 beta and concomitantly stimulated IL-4 in pouch exudates. These findings from in vitro and in vivo experiments indicate that both LXA4 and ATL are regulators of TNF alpha-directed neutrophil actions and stimulate IL-4 in exudates and thus regulate mediators that are held to play an important role in the pathogenesis of periodontal disease.
Studies on Medicinal Plant Resources of the Himalayas: GC-MS Analysis of Seed Fat of Chyuri (Diploknema butyracea) from Nepal (2012)

a B S t r a c t chyuri (Diploknema butyracea (r oxburgh) H. J. lam) is widely used in nepal for its medicinal properties and as a source of chyuri ghee (fat) extracted from the seeds. the main purpose of the present study was the gc-MS analysis of fatty acids in seed fat of chyuri after acidic methanolysis. Palmitic acid methyl ester (1), linoleic acid methyl ester (2), oleic acid methyl ester (3) and steric acid methyl ester (4) were identified as the main components. Ethnomedicinal use and distribution of chyuri in nepal is also discussed.
Managing the effects of multiple stressors on aquatic ecosystems under water scarcity. The GLOBAQUA project (2014)

Water scarcity is a serious environmental problem in many European regions, and will likely increase in the near future as a consequence of increased abstraction and climate change. Water scarcity exacerbates the effects of multiple stressors, and thus results in decreased water quality. It impacts river ecosystems, threatens the services they provide, and it will force managers and policy-makers to change their current practices. The EU-FP7 project GLOBAQUA aims at identifying the prevalence, interaction and linkages between stressors, and to assess their effects on the chemical and ecological status of freshwater ecosystems in order to improve water management practice and policies. GLOBAQUA assembles a multidisciplinary team of 21 European plus 2 non-European scientific institutions, as well as water authorities and river basin managers. The project includes experts in hydrology, chemistry, biology, geomorphology, modelling, socio-economics, governance science, knowledge brokerage, and policy advocacy. GLOBAQUA studies six river basins (Ebro, Adige, Sava, Evrotas, Anglian and Souss Massa) affected by water scarcity, and aims to answer the following questions: how does water scarcity interact with other existing stressors in the study river basins? How will these interactions change according to the different scenarios of future global change? Which will be the foreseeable consequences for river ecosystems? How will these in turn affect the services the ecosystems provide? How should management and policies be adapted to minimise the ecological, economic and societal consequences? These questions will be approached by combining data-mining, field- and laboratory-based research, and modelling. Here, we outline the general structure of the project and the activities to be conducted within the fourteen work-packages of GLOBAQUA.
PHF6 Expression Levels Impact Human Hematopoietic Stem Cell Differentiation (2020)

Transcriptional control of hematopoiesis involves complex regulatory networks and functional perturbations in one of these components often results in malignancies. Loss-of-function mutations in <i>PHF6</i>, encoding a presumed epigenetic regulator, have been primarily described in T cell acute lymphoblastic leukemia (T-ALL) and the first insights into its function in normal hematopoiesis only recently emerged from mouse modeling experiments. Here, we investigated the role of PHF6 in human blood cell development by performing knockdown studies in cord blood and thymus-derived hematopoietic precursors to evaluate the impact on lineage differentiation in well-established <i>in vitro</i> models. Our findings reveal that <i>PHF6</i> levels differentially impact the differentiation of human hematopoietic progenitor cells into various blood cell lineages, with prominent effects on lymphoid and erythroid differentiation. We show that loss of PHF6 results in accelerated human T cell development through reduced expression of <i>NOTCH1</i> and its downstream target genes. This functional interaction in developing thymocytes was confirmed <i>in vivo</i> using a <i>phf6</i>-deficient zebrafish model that also displayed accelerated developmental kinetics upon reduced <i>phf6</i> or notch1 activation. In summary, our work reveals that appropriate control of <i>PHF6</i> expression is important for normal human hematopoiesis and provides clues towards the role of <i>PHF6</i> in T-ALL development.