gebhart/patrepeval huggingface dataset:
Transverse dynamics of slender piezoelectric bimorphs with resistive-inductive electrodes (2016)

This paper presents and compares a one-dimensional (1D) bending theory for piezoelectric thin beam-type structures with resistive-inductive electrodes to ANSYS<TEX>$^{(R)}$</TEX> three-dimensional (3D) finite element (FE) analysis. In particular, the lateral deflections and vibrations of slender piezoelectric beams are considered. The peculiarity of the piezoelectric beam model is the modeling of electrodes in such a manner that is does not fulfill the equipotential area condition. The case of ideal, perfectly conductive electrodes is a special case of our 1D model. Two-coupled partial differential equations are obtained for the lateral deflection and for the voltage distribution along the electrodes: the first one is an extended Bernoulli-Euler beam equation (second-order in time, forth order in space) and the second one the so-called Telegrapher's equation (second-order in time and space). Analytical results of our theory are validated by 3D electromechanically coupled FE simulations with ANSYS<TEX>$^{(R)}$</TEX>. A clamped-hinged beam is considered with various types of electrodes for the piezoelectric layers, which can be either resistive and/or inductive. A natural frequency analysis as well as quasi-static and dynamic simulations are performed. A good agreement between the extended beam theory and the FE results is found. Finally, the practical relevance of this type of electrodes is shown. It is found that the damping capability of properly tuned resistive or resistive-inductive electrodes exceeds the damping performance of beams, where the electrodes are simply linked to an optimized impedance.
Lack of the t(2;5) or other mutations resulting in expression of anaplastic lymphoma kinase catalytic domain in CD30+ primary cutaneous lymphoproliferative disorders and Hodgkin's disease (1996)

The t(2;5) (p23;q35) chromosomal translocation has been found in a high proportion of lymph node-based CD30+ large cell lymphomas of T-cell lineage. This translocation is believed to result in the expression of a fusion protein containing the catalytic domain of anaplastic lymphoma kinase (ALK) under the control of the promoter for nucleophosmin, a nucleolar phosphoprotein. Expression of ALK activity, which does not normally occur in lymphocytes, is postulated to be involved in the pathogenesis of lymphomas bearing the t(2;5) translocation. Several primary cutaneous lymphoproliferative disorders and Hodgkin's disease are also known to contain CD30+ large lymphoid cells. To determine the role of the t(2;5) translocation in these diseases, we developed a DNA-based polymerase chain reaction (PCR)/Southern blot assay to detect this translocation at the genomic level in lymphomatoid papulosis (14 cases), primary cutaneous CD30+ large cell lymphoma of T-lineage (10 cases) and Hodgkin's disease (13 cases). Two cases of pityriasis lichenoides were also studied. The t(2;5) translocation was not present in any of these specimens. To determine if some other somatic mutation might have resulted in inappropriate expression of ALK catalytic domain, we devised an RNA-based reverse transcriptase-PCR assay to detect transcripts encoded by this ALK region. None were found in the six additional cases of lymphomatoid papulosis that were studied. In aggregate, these results strongly suggest that inappropriate expression of ALK is not involved in the pathogenesis of these CD30+ lymphoproliferative disorders, and that lymph node-based CD30+ large cell lymphoma is a disease that is biologically distinct from skin-based CD30+ lymphoproliferative disorders and Hodgkin's disease. Using methods developed for this report, we also cloned and sequenced the t(2;5) genomic junctional sequences present in the SUP-M2 and SU-DHL-1 cell lines. These intron sequences will be useful for mapping t(2;5) breakpoint clusters.
[Cytotoxicity and mutagenicity studies of T-3761]. (1995)

We investigated cytotoxicity and mutagenicity of T-3761. The mutagenicity was evaluated using reverse mutation test with bacteria, chromosome aberration test with cultured cells and micronucleus test with mice. The following results were obtained. 1. Cytotoxicity test: The cell growth was examined using Chinese hamster (V79) cells. The 50% inhibition doses of T-3761 for cell growth (ID50) were 490 micrograms/ml (cultured for 24 hours) and 220 micrograms/ml (cultured for 48 hours). The inhibitory effect of T-3761 was 2-4 times lower than those of ciprofloxacin or norfloxacin and approximately equal to cephalothin. 2. Reverse mutation test with bacteria: The preincubation method with Salmonella typhimurium TA100, TA98, TA1535, TA1537 and Escherichia coli WP2 uvrA, and the induced mutation frequency (IMF) test with Salmonella typhimurium TA100, TA98 were performed. The number of revertant colonies were not increased in any strains treated with T-3761 in the presence or absence of S9 mix. 3. Chromosome aberration test: V79 cells were treated with 50-200 micrograms/ml of T-3761 for 24 or 48 hours, and were treated with 400-3,200 micrograms/ml of T-3761 for 6 hours with S9 mix. The number of cells showing chromosomal aberrations were not increased in any conditions tested for T-3761. 4. Micronucleus test: The male ICR mice were given a single (500-5,000 mg/kg) or five consecutive (150-1,500 mg/kg) oral administration of T-3761. The number of polychromatic erythrocytes with micronuclei were not increased at any dosage groups of T-3761. From these results, it is concluded that T-3761 has low cytotoxicity, and has no mutagenicity.
CPS: beyond usability (2014)

Wireless implantable medical devices (IMDs) are cyber-physical systems that deliver life-saving treatments to cardiac patients with dangerous heart conditions. Current access control models for these systems are insufficient; more security is necessary. In response to this problem, the technical security community has investigated new directions for improving security on these resource-constrained devices. Defenses, however, must not only be technically secure; in order to be deployable, defenses must be designed to work within the needs and constraints of their relevant application spaces. Designing for an application space---particularly a specialized one---requires a deep understanding of the stakeholders, their values, and the contexts of technology usage. Grounding our work in value sensitive design (VSD), we collaborated as an interdisciplinary team to conduct three workshops with medical providers for the purpose of gathering their values and perspectives. The structure of our workshop builds on known workshop structures within the human-computer interaction (HCI) community, and the number of participants in our workshops (N=24) is compatible with current practices for inductive, exploratory studies. We present results on: what the participants find important with respect to providing care and performing their jobs; their reactions to potential security system concepts; and their views on what security system properties should be sought or avoided due to side effects within the context of their work practice. We synthesize these results, use the results to articulate design considerations for future technical security systems, and suggest directions for further research. Our research not only provides a contribution to security research for an important class of cyber-physical systems (IMDs); it also provides an example of leveraging techniques from other communities to better explore the landscape of security designs for technologies.
A Choices Hypervisor on the ARM Architecture (2006)

Choices is an object oriented operating system that runs on the x86 and ARM architectures. The aim of this project is to build a hypervisor using Choices on the ARM architecture. In this project we aim to build a hypervisor on the QEMU emulator emulating the ARM7 architecture using a VMX approach. We have selected as guest operating system a small Linux image. The primary goal of the system is to emulate the sensitive instructions of the ARM architecture using VMX like instructions in the hypervisor. We have identified the sensitive instructions for the ARM architecture. We have also put in place a mechanism by which QEMU traps on sensitive instruction to the hypervisor. In future, we will proceed to implement the validation and emulation of the sensitive instructions in Choices while extending QEMU with the necessary VMX instructions. 1.
Building-in-Briefcase (BiB) (2014)

A building's environment has profound influence on occupant comfort and health. Continuous monitoring of building occupancy and environment is essential to fault detection, intelligent control, and building commissioning. Though many solutions for environmental measuring based on wireless sensor networks exist, they are not easily accessible to households and building owners who may lack time or technical expertise needed to set up a system and get quick and detailed overview of environmental conditions. Building-in-Briefcase (BiB) is a portable sensor network platform that is trivially easy to deploy in any building environment. Once the sensors are distributed, the environmental data is collected and communicated to the BiB router via TCP/IP protocol and WiFi technology which then forwards the data to the central database securely over the internet through a 3G radio. The user, with minimal effort, can access the aggregated data and visualize the trends in real time on the BiB web portal. Paramount to the adoption and continued operation of an indoor sensing platform is battery lifetime. This design has achieved a multi-year lifespan by careful selection of components, an efficient binary communications protocol and data compression. Our BiB sensor is capable of collecting a rich set of environmental parameters, and is expandable to measure others, such as CO2. This paper describes the power characteristics of BiB sensors and their occupancy estimation and activity recognition functionality. Our vision is large-scale deployment of BiB in thousands of buildings, which would provide ample research opportunities and opportunities to identify ways to improve the building environment and energy efficiency.
White kidney bean extract as a nutraceutical: effects on gut microbiota, alpha-amylase inhibition, and user experiences (2023)

White kidney bean extract (WKBE) is a nutraceutical often advocated as an anti-obesity agent. The main proposed mechanism for these effects is alpha-amylase inhibition, thereby slowing carbohydrate digestion and absorption. Thus, it is possible that WKBE could impact the gut microbiota and modulate gut health. We investigated the effects of supplementing 20 healthy adults with WKBE for 1 week in a randomised, placebo-controlled crossover trial on the composition of the gut microbiota, gastrointestinal (GI) inflammation (faecal calprotectin), GI symptoms, and stool habits. We conducted <i>in vitro</i> experiments and used a gut model system to explore potential inhibition of alpha-amylase. We gained qualitative insight into participant experiences of using WKBE via focus groups. WKBE supplementation decreased the relative abundance of <i>Bacteroidetes</i> and increased that of <i>Firmicutes</i>, however, there were no significant differences in post-intervention gut microbiota measurements between the WKBE and control. There were no significant effects on GI inflammation or symptoms related to constipation, or stool consistency or frequency. Our <i>in vitro</i> and gut model system analyses showed no effects of WKBE on alpha-amylase activity. Our findings suggest that WKBE may modulate the gut microbiota in healthy adults, however, the underlying mechanism is unlikely due to active site inhibition of alpha-amylase.
Intelligent Control and Security of Fog Resources in Healthcare Systems via a Cognitive Fog Model (2020)

There have been significant advances in the field of Internet of Things (IoT) recently, which have not always considered security or data security concerns: A high degree of security is required when considering the sharing of medical data over networks. In most IoT-based systems, especially those within smart-homes and smart-cities, there is a bridging point (fog computing) between a sensor network and the Internet which often just performs basic functions such as translating between the protocols used in the Internet and sensor networks, as well as small amounts of data processing. The fog nodes can have useful knowledge and potential for constructive security and control over both the sensor network and the data transmitted over the Internet. Smart healthcare services utilise such networks of IoT systems. It is therefore vital that medical data emanating from IoT systems is highly secure, to prevent fraudulent use, whilst maintaining quality of service providing assured, verified and complete data. In this article, we examine the development of a Cognitive Fog (CF) model, for secure, smart healthcare services, that is able to make decisions such as opting-in and opting-out from running processes and invoking new processes when required, and providing security for the operational processes within the fog system. Overall, the proposed ensemble security model performed better in terms of Accuracy Rate, Detection Rate, and a lower False Positive Rate (standard intrusion detection measurements) than three base classifiers (K-NN, DBSCAN, and DT) using a standard security dataset (NSL-KDD).
Shifts in archaeal communities associated with lithological and geochemical variations in subsurface Cretaceous rock (2003)

Subsurface microbial community structure in relation to geochemical gradients and lithology was investigated using a combination of molecular phylogenetic and geochemical analyses. Discreet groundwater and substratum samples were obtained from depths ranging from 182 to 190 m beneath the surface at approximately 10-cm intervals using a multilevel sampler (MLS) that straddled Cretaceous shale and sandstone formations at a site in the southern San Juan Basin in New Mexico. DNA and RNA were extracted directly from quartzite sand substratum loaded into individual cells of the MLS and colonized in situ. Polymerase chain reaction (PCR)-mediated T-RFLP analysis of archaeal rRNA genes (rDNA) in conjunction with partial sequencing analysis of archaeal rDNA libraries and quantitative RNA hybridization with oligonucleotide probes were used to probe community structure and function. Although total microbial populations remained relatively constant over the entire depth interval sampled, significant shifts in archaeal populations, predominantly methanogens, were observed. These shifts coincided with the geochemical transition from relatively high methane (26 mM), low sulphate (< 3 mg l(-1)) conditions in the region adjacent to the organic matter-rich shale to relatively low-methane (< 0.5 mM), high-sulphate (48 mg l(-1)) conditions in the organic-poor sandstone beneath the shale. These results indicated that active, phylogenetically diverse archaeal communities were present in the subsurface Cretaceous rock environment at this site and that major archaeal clades shifted dramatically over scales of tens of centimetres, corresponding to changes in the lithology and geochemical gradients.
Improving User-Insurance Communication on Accident Reports (2014)

This paper presents an easy to use methodology and system for insurance companies targeting at managing traffic accidents reports process. The main objective is to facilitate and accelerate the process of creating and finalizing the necessary accident reports in cases without mortal victims involved. The diverse entities participating in the process from the moment an accident occurs until the related final actions needed are included. Nowadays, this market is limited to the consulting platforms offered by the insurance companies.
Design rules for strong electro-optic materials (2020)

Abstract The explosive rise of silicon photonics has led to renewed interest in the electro-optic (EO) or Pockels effect due to its potential uses in many next generation device applications. To find materials with a strong EO response in thin film form, which are essential for low power and small footprint devices, one needs to find a general design rule for strong Pockels materials. To elucidate what makes the Pockels effect strong, we study the effect in LiB 3 O 5 (LBO) and CsB 3 O 5 (CBO) and use these materials as prototypical examples of where conventional wisdom breaks down. We find the Pockels tensor components to be extremely small in both materials, despite the large degree of anharmonicity in the crystals, which has been used as a proxy for the presence of nonlinear electronic effects. We relate the lack of EO response to the large optical phonon frequencies (despite the relatively large Raman susceptibility) in LBO and to the small Raman susceptibility (despite the low phonon frequencies) in CBO, respectively. We shed light on the underlying physical phenomena behind the Raman susceptibility, which we find to be intimately linked to the electron–phonon coupling strength of the near-edge electronic states, and identify a route to discovering new strong EO materials.
Self-adaptive Canny operator edge detection technique (2007)

When edge detection is performed using a Canny algorithm,the gradient image should be processed with non-maximum module suppression and then double thresholds evaluated to detect edges.However,the double thresholds are greatly affected by personal experience.Experiments show that the results of edge detection for different images are obviously different if the identical threshold is employed,which restricted the use of Canny algorithm in practice.To solve this problem,an algorithm is proposed which can adaptively determine the double thresholds based on gradient histogram and minimum interclass variance.With this algorithm,it can self-adaptively calculate the double thresholds for different images without the necessity to setup any parameter artificially.Fuzzy algorithm is adopted to choose edge pixels.Theory and experiments show that the algorithm is effective and correct.
Evolutionary Relationships of the Dutch Elm Disease Fungus Ophiostoma novo‐ulmi to Other Ophiostoma Species Investigated by Restriction Fragment Length Polymorphism Analysis of the rDNA Region (2000)

Restriction fragment length polymorphisms (RFLPs) in the ribosomal RNA gene (rDNA) region were used to assess relationships between the Dutch elm disease fungi Ophiostoma novo‐ulmi and Ophiostoma ulmi , the recently described Himalayan Dutch elm disease pathogen, Ophiostoma himal‐ulmi , the morphologically similar sapstain fungi, Ophiostoma piceae and Ophiostoma quercus , and several Ophiostoma species from hardwood trees, including Ophiostoma stenoceras and Ophiostoma proliferum . A distance matrix and cluster analysis indicated that the rDNA region of O. himal‐ulmi is more closely related to those of O. novo‐ulmi and O. ulmi than to those of O. piceae and O. quercus and is more distantly related to O. stenoceras and the other Ophiostoma species, which formed a separate clade. The rDNA region of O. quercus was found to be at least as closely related to that of O. novo‐ulmi and O. ulmi as it is to that of O. piceae . The implications of these results for the evolution of the Dutch elm disease fungi are discussed.
Circular economy in the building and construction sector: A scientific evolution analysis (2021)

The building industry is responsible for considerable environmental impacts due to its consumption of resources and energy, and the production of wastes. Circular Economy (CE), a new paradigm can significantly improve the sustainability of this sector. This paper performs a quantitative scientific evolution analysis of the application of CE in the building sector to detect new trends and highlight the evolvement of this research topic. Around 7000 documents published 2005 to 2020 at Web of Science and Scopus were collected and analyzed. The bibliometric indicators, network citation, and multivariate statistical analysis were obtained using Bibliometrix R-package and VOSviewer. The co-occurrence analysis showed five keyword-clusters, in which the three main ones are: (i) energy and energy efficiency in buildings; (ii) recycling, waste management and alternative construction materials; (iii) sustainable development. The analysis showed that researchers pay close attention to “sustainability”, “energy efficiency”, “life cycle assessment”, “renewable energy”, and “recycling” in the past five years. This paper highlights that (i) the development and use of alternative construction materials; (ii) the development of circular business models; (iii) smart cities, Industry 4.0 and their relations with CE, are the current research hotspots that may be considered as potential future research topics.
Modelling and analysis of the crush zone of a typical Australian passenger train (2012)

In this paper, a three-dimensional nonlinear rigid body model has been developed for the investigation of the crashworthiness of a passenger train using the multibody dynamics approach. This model refers to a typical design of passenger cars and train constructs commonly used in Australia. The high-energy and low-energy crush zones of the cars and the train constructs are assumed and the data are explicitly provided in the paper. The crash scenario is limited to the train colliding on to a fixed barrier symmetrically. The simulations of a single car show that this initial design is only applicable for the crash speed of 35 km/h or lower. For higher speeds (e.g. 140 km/h), the crush lengths or crush forces or both the crush zone elements will have to be enlarged. It is generally better to increase the crush length than the crush force in order to retain the low levels of the longitudinal deceleration of the passenger cars.
Méthode mathématique de détermination de la zone de transition aérobie - anaérobie lors d'une épreuve d'effort triangulaire. (1991)

International audience
Exchange-Mediated Transport in Battery Electrolytes: Ultrafast or Ultraslow? (2022)

Understanding the mechanisms of charge transport in batteries is important for the rational design of new electrolyte formulations. Persistent questions about ion transport mechanisms in battery electrolytes are often framed in terms of vehicular diffusion by persistent ion-solvent complexes versus structural diffusion through the breaking and reformation of ion-solvent contacts, i.e., solvent exchange events. Ultrafast two-dimensional (2D) IR spectroscopy can probe exchange processes directly via the evolution of the cross-peaks on picosecond time scales. However, vibrational energy transfer in the absence of solvent exchange gives rise to the same spectral signatures, hiding the desired processes. We employ 2D IR on solvent resonances of a mixture of acetonitrile isotopologues to differentiate chemical exchange and energy-transfer dynamics in a comprehensive series of Li<sup>+</sup>, Mg<sup>2+</sup>, Zn<sup>2+</sup>, Ca<sup>2+</sup>, and Ba<sup>2+</sup> bis(trifluoromethylsulfonyl)imide electrolytes from the dilute to the superconcentrated regime. No exchange phenomena occur within at least 100 ps, regardless of the ion identity, salt concentration, and presence of water. All of the observed spectral dynamics originate from the intermolecular energy transfer. These results place the lower experimental boundary on the ion-solvent residence times to several hundred picoseconds, much slower than previously suggested. With the help of MD simulations and conductivity measurements on the Li<sup>+</sup> and Zn<sup>2+</sup> systems, we discuss these results as a continuum of vehicular and structural modalities that vary with concentration and emphasize the importance of collective electrolyte motions to ion transport. These results hold broadly applicable to many battery-relevant ions and solvents.