gebhart/patrepeval huggingface dataset:
Synthesis and Photophysical Properties of Biaryl-Substituted Nucleos(t)ides. Polymerase Synthesis of DNA Probes Bearing Solvatochromic and pH-Sensitive Dual Fluorescent and 19F NMR Labels (2011)

The design of four new fluorinated biaryl fluorescent labels and their attachment to nucleosides and nucleoside triphosphates (dNTPs) by the aqueous cross-coupling reactions of biarylboronates is reported. The modified dNTPs were good substrates for KOD XL polymerase and were enzymatically incorporated into DNA probes. The photophysical properties of the biaryl-modified nucleosides, dNTPs, and DNA were studied systematically. The different substitution pattern of the biaryls was used for tuning of emission maxima in the broad range of 366-565 nm. Using methods of computational chemistry the emission maxima were reproduced with a satisfactory degree of accuracy, and it was shown that the large solvatochromic shifts observed for the studied probes are proportional to the differences in dipole moments of the ground (S(0)) and excited (S(1)) states that add on top of smaller shifts predicted already for these systems in vacuo. Thus, we present a set of compounds that may serve as multipurpose base-discriminating fluorophores for sensing of hairpins, deletions, and mismatches by the change of emission maxima and intensities of fluorescence and that can be also conviently studied by (19)F NMR spectroscopy. In addition, aminobenzoxazolyl-fluorophenyl-labeled nucleotides and DNA also exert dual pH-sensitive and solvatochromic fluorescence, which may imply diverse applications.
Enhanced Electrochromic Performance of Mesoporous Titanium Dioxide/Reduced Graphene Oxide Nanocomposite Film Prepared by Electrophoresis Deposition (2018)

A novel and scalable method combining surfactant template and electrophoresis deposition was used to prepare mesoporous titanium dioxide/reduced graphene oxide (TiO2/RGO) nanocomposite film with the assistance of sodium dodecyl benzene sulfonate using tetrabutyl titanate and graphene oxide (GO) as raw material. The electrochromic mechanism of TiO2/RGO nanocomposite film was investigated by XPS technique. The TiO2/RGO nanocomposite film showed that TiO2 nanocrystals can be anchored on the surface of RGO via chemical bonding such as Ti−O−C and Ti−C. The TiO2/RGO nanocomposite film exhibited shorter coloration/bleaching response times (3.9 s for coloration and 6.6 s for bleaching), higher coloration efficiency (34.9 cm2 C−1) and better coloration/bleaching cycle stability compared with pure TiO2 film. The electrochromic mechanism of TiO2/RGO nanocomposite film was accorded with valence transition model, and an island-bridge model was proposed to interpret the enhancement mechanism of electrochromic performance. This enhancement is mainly due to a larger specific surface area, higher electrical conductivity and better structural stability in TiO2/RGO nanocomposite film, which facilitates faster transport of Li+ ions and electrons, and longer coloration/bleaching cycle life. This work provides an effective approach and inspiration to improve the electrochromic performance of transition metal oxides, as well as explore other high-performance electrochromic materials.
A Study on Application of H Infinity Control Theory to an Electric-control Variable Displacement Pump. (2004)

H infinity control theory was applied to control of a variable displacement piston pump. Angle of the pump's swash plate was detected by means of a position sensor attached on a control piston. The position signal was fed back to a controller and a control input signal was added to a proportional flow control valve so that the control piston position follows the demanded signal. A control system for pump displacement was designed by applying H infinity control theory considering changes in pump speed and load pressure. The control system was examined experimentally on a test bench. Results demonstrated that the system shows stable and quick responses under different pump operating conditions.
Propagation of the mutual coherence function for an infinite plane wave through a turbid medium (1977)

By means of a series of Fourier and inverse Fourier transformations, and by recourse to simple physical arguments concerning statistical stationarity and isotropy and the linearity of the scattering process, we are able to show that the propagation of the mutual coherence function for a plane wave through a turbid medium is governed by a pair of linear, first-order, one-dimensional, simultaneous differential equations. A sample solution to the equation is presented, and it is shown from a limiting form of this solution how the turbidity parameters in the differential equation can be obtained from a single scattering analysis.
Whole Tumor Antigen Vaccines: Where Are We? (2015)

With its vast amount of uncharacterized and characterized T cell epitopes available for activating CD4⁺ T helper and CD8⁺ cytotoxic lymphocytes simultaneously, whole tumor antigen represents an attractive alternative source of antigens as compared to tumor-derived peptides and full-length recombinant tumor proteins for dendritic cell (DC)-based immunotherapy. Unlike defined tumor-derived peptides and proteins, whole tumor lysate therapy is applicable to all patients regardless of their HLA type. DCs are essentially the master regulators of immune response, and are the most potent antigen-presenting cell population for priming and activating naïve T cells to target tumors. Because of these unique properties, numerous DC-based immunotherapies have been initiated in the clinics. In this review, we describe the different types of whole tumor antigens that we could use to pulse DCs ex vivo and in vivo. We also discuss the different routes of delivering whole tumor antigens to DCs in vivo and activating them with toll-like receptor agonists.
A 100 &amp;#956;m Beamwidth ZnO on Si Convolver (1979)

convolver has been demonstrated. A 100 pm wide output top plate served to waveguide the acoustic beams. The acoustic beams themselves were excited by interdigital transducers that were the same width as the top p late. Operating the transducers at a center frequency of 125 MHz, the tuned delay line insertion loss was 26 dB, and the overall efficiency of the convolver was -44 dBm. This convolution efficiency is 11 dB better than any previous ZnO/Si convolver. A new monolithic ZnO/Si, Av/v waveguided
Verbesserung von Kunstharzbeschichtungen durch Nanopartikel mit maßgeschneiderter Oberflächenmodifizierung (2016)

Abstract Polymere Nanokomposite erfahren heutzutage zunehmende Bedeutung für die Erzeugung funktioneller Beschichtungen. Zu diesem Zweck werden maßgeschneiderte modifizierte Nanopartikel in eine Harzmatrix eingebracht und die Eigenschaften einer so erzeugten Beschichtung wesentlich verbessert. In dieser Arbeit wird der Zusammenhang der gesamten Prozesskette, von der Synthese bis zur Charakterisierung der Schichten, mit besonderem Blick auf die partikuläre Oberflächenchemie untersucht. Auf diese Weise kann dieser Einfluss aus einer Hand überprüft und Randeffekte weitgehend vermieden werden.
Synthesis and characterization of new soluble polyamides containing phthalimide pendent group (2001)

Abstract A dicarboxylic acid monomer, 5‐phthalimidoisophthalic acid, containing a phthalimide pendent group was prepared by the condensation of 5‐aminoisophthalic acid and phthalic anhydride in glacial acetic anhydride. The monomer was reacted with various aromatic diamines to produce polyamides using triphenyl phosphite and pyridine as condensing agents. These polyamides were produced with inherent viscosities of 0.64–1.14 dL · g −1 . All the polymers, characterized by wide‐angle X‐ray diffraction, revealed an amorphous nature resulting from the presence of the bulky pendent group. These polyamides exhibited excellent solubility in a variety of solvents such as N ‐ methyl‐2‐pyrrolidinone, N , N ‐dimethylacetamide (DMAc), N,N ‐dimethylformamide, dimethyl sulfoxide, pyridine, and cyclohexanone. These polyamides showed glass‐transition temperatures ( T g 's) between 247 and 273 °C (by DSC) and 248 and 337 °C (by a dynamic mechanical analyzer). The thermogravimetric analytic measurement revealed the decomposition temperature at 10% weight‐loss temperatures ( Td 10 ) ranging from 442 to 530 °C in nitrogen. The polyamides containing phthalimide groups exhibited higher T g and Td 10 values than those having no phthalimide groups. Transparent, tough, and flexible films of these polyamides could be cast from the DMAc solutions. These casting films had tensile strengths ranging from 81 to 126 MPa, elongations at break ranging from 7 to 13%, and tensile moduli ranging from 2.0 to 2.9 GPa. © 2001 John Wiley &amp; Sons, Inc. J Polym Sci A: Polym Chem 39: 1557–1563, 2001
Some Perspectives and Recent Findings in Shallow Water Acoustics (1972)

Shallow water acoustics has had in this country a long, though sporadic, history dating back to World War II, when the acoustic mine stimulated feverish activity in the subject. Yet, in spite of the impressive body of theory, model studies, and field data that has accumulated in subsequent years, many aspects of this most difficult branch of underwater acoustics are not understood. Many of its complications are due to the temporal and spatial variability of the shallow water medium and its boundaries. For example, we have found the transmission of shallow water sound to vary with direction and time at one location and to be different at apparently similar locations. Such variations make acoustic prediction difficult, and necessitate on-the-spot measurements at the place and time that data is required. To this end, we have developed and tried out at a number of coastal locations an airborne method of data collection using sonobuoys, explosive sound signals, and simple, portable recording equipment. The transmission results have been summarized by loss contour charts showing the transmission environment around a receiving point in shallow water.
Coordinated manipulator and spacecraft motion planning for free-floating space robots (2009)

This paper studies the coordinated manipulator and spacecraft motion planning for free-floating space robots (FFSR). The kinematics of the FFSR is analyzed based on momentum conservation law firstly. Then a nonholonomic motion planning, including requirements on spacecraft's orientation and end-effector's position is proposed using the chained form transformation and time-state control form. A planar FFSR with a 2 DOFs manipulator is selected to develop the algorithm. And simulation results illustrate that the position of the end-effector and the spacecraft orientation reach the desired state simultaneously. Finally, deficiencies of the method and prospects for the future are summarized.
Performance Improvement of a Combined Power and Cooling Cycle for Low Temperature Heat Sources Using Internal Heat Recovery and Scroll Expander (2019)

Abstract Low temperature heat sources inherently result in lower cycle efficiencies, which can be improved by means of combined power and cooling generation. In order to produce power and cooling, appropriate thermodynamic cycles and working fluids must be used. Goswami cycle is a combined cycle that produces power and refrigeration by using ammonia-water mixture for low temperature heat sources. In the present study, a scroll expander is modeled specifically for the cycle operating conditions and a theoretical investigation is conducted to determine the cycle performance. A scroll expander design suitable for the operating conditions improves the power output and thereby overall thermal efficiency. The scroll expander efficiency varied between 0.05 and 0.61 for the pressure ratio between 2.2 and 8.6, with a maximum efficiency of 0.697 achieved at a pressure ratio of about 4.4. An internal heat recovery from the rectifier is proposed along with a flow split in the strong solution and analyzed for overall cycle energy efficiency improvement. Internal heat recovery from the rectifier increased the first law effective efficiency and the effective exergy efficiency by 7.9% and 7.8%, respectively, over the basic configuration.
Beyond Wernicke's (2002)

Because no one has ever composed a glossary of psychiatry's numerous eponyms, the author collected eponymous signs and syndromes for a behavioral lexicon. Eponyms are included if they recall a real person, if they have special relevance to psychiatry, and if they describe an abnormal symptom or syndrome that we consider clinically important today, even if American physicians no longer favor the eponym. The author used MEDLINE and Campbell's Psychiatric Dictionary to locate candidates for the glossary. A brief definition and suggested reference accompany each entry.
Onboard Science and Applications Algorithm for Hyperspectral Data Reduction (2012)

An onboard processing mission concept is under development for a possible Direct Broadcast capability for the HyspIRI mission, a Hyperspectral remote sensing mission under consideration for launch in the next decade. The concept would intelligently spectrally and spatially subsample the data as well as generate science products onboard to enable return of key rapid response science and applications information despite limited downlink bandwidth. This rapid data delivery concept focuses on wildfires and volcanoes as primary applications, but also has applications to vegetation, coastal flooding, dust, and snow/ice applications. Operationally, the HyspIRI team would define a set of spatial regions of interest where specific algorithms would be executed. For example, known coastal areas would have certain products or bands downlinked, ocean areas might have other bands downlinked, and during fire seasons other areas would be processed for active fire detections. Ground operations would automatically generate the mission plans specifying the highest priority tasks executable within onboard computation, setup, and data downlink constraints. The spectral bands of the TIR (thermal infrared) instrument can accurately detect the thermal signature of fires and send down alerts, as well as the thermal and VSWIR (visible to short-wave infrared) data corresponding to the active fires. Active volcanism also produces a distinctive thermal signature that can be detected onboard to enable spatial subsampling. Onboard algorithms and ground-based algorithms suitable for onboard deployment are mature. On HyspIRI, the algorithm would perform a table-driven temperature inversion from several spectral TIR bands, and then trigger downlink of the entire spectrum for each of the hot pixels identified. Ocean and coastal applications include sea surface temperature (using a small spectral subset of TIR data, but requiring considerable ancillary data), and ocean color applications to track biological activity such as harmful algal blooms. Measuring surface water extent to track flooding is another rapid response product leveraging VSWIR spectral information.
Studies on the arbuscular mycorrhizal fungal association in some medicinal plant species of paithal hills, western ghats kannur district, kerala (2020)

In the present study to analyzed that the arbuscular mycorrhizal fungal spores in root colonization and spore population in rhizosphere soils samples in various medicinal at Paithal hills,Western Ghats of Kannur district, Kerala, India. Root and rhizosphere soil samples were collected during the month of August, 2018-March, 2019 from the surface to 30 cm depth as well as pH were also recorded. Totally 30 plant species belonging to 19 families were collected and identified. The present result showed arbuscular mycorrhizal spore population in the rhizosphere soil and root colonization of all the plant species. A total of 19 AM fungal spores were recovered from the rhizosphere soil samples in this study region. The Glomus was dominant had seen in rhizosphere soil samples in all the medicinal plant species. The maximum spore population was found in the rhizosphere soil samples of Mimosa pudica (590/100g of soil) which belongs to the family Mimosaceae and the lowest spore population was observed in the Terminalia bellirica 135/100g of soil) belongs to Combretaceae family. The highest 78 % AM fungal colonization was found in roots of Euphorbia hirta belongs to the family Euphorbiaceae. While the lowest 11 % AM fungal colonization was found in the root of Sida acuta belongs to the family Malvaceae.
Supplementary Figure 2 from Natural Human Plasmacytoid Dendritic Cells Induce Antigen-Specific T-Cell Responses in Melanoma Patients (2023)

&lt;p&gt;Supplementary Figure 2 PDF file - 46K, Supplementary Figure 2 Plasmacytoid DCs acquire CCL21-driven chemotactic ability upon activation&lt;/p&gt;
Thermo and salt responsive poly(ionic liquid)s. (2015)

Poly(ionic liquid)s are defined as ionic liquids which feature polymerizable groups in either the cation, the anion, or both. The aim of this study is to synthesize a tributylhexyl phosphonium sulfopropyl acrylate (PSPA) poly(ionic liquid) (PIL) hydrogel and characterise its temperature and salt concentration induced shrinking. The gels were polymerised in circular moulds and were hydrated in deionized water (DI water). The percent shrinking upon exposure to a stimulus was calculated using the formula: %s = (Ai- Af)/Ai x 100, where Ai is the initial area of the swollen hydrogel and Af is the final area of the hydrogel after the application of the stimulus.
Stroboscopic-Induced Seizure Discharges (1964)

In 1959 studies of conditioning factors in epilepsy were begun in our laboratory in animals with embedded electrodes.<sup>1-3</sup>While we were in the process of careful conditioning and deconditioning experiments in animals, a college student presented to the Neurology Clinic in the Student Health Division because of a grand mal convulsion which occurred while she was fixing her television for "flop-over." In the course of the electroencephalographic studies of this patient, an observation was made quite serendipitously that when vision was completely occluded in one eye, no paroxysmal disturbance and no clinical seizure could be produced by intermittent light stimulation although binocular stimulation evoked a myoclonic seizure and dysrhythmia. This serendipitous observation presented an ideal model for extinction trials, and these were accordingly undertaken. It was found that repeated monocular stimulation served as an extinction phenomenon.<sup>4</sup>This has afforded us the opportunity to extend our studies to the
The Tishchenko Reaction and Its Modifications in Organic Synthesis (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
Formaldehyde (2000)

Abstract Formaldehyde is a versatile, reactive substance, basic to the chemical industry because of its low cost and ease of production. It is manufactured by vapor‐phase oxidation of methanol using two principal processes. One method employs a pure silver catalyst and the other an iron molybdate catalyst. Several other processes are under development, but none have been commercialized. All processes are capital intensive, requiring integrated reaction, heat recovery, and purification systems to achieve optimum economic benefits. Formaldehyde is sold as concentrated, aqueous solutions, and may contain methanol to inhibit polymerization. It is also sold in alcohol solutions, which contain little water. Its principal uses are in the production of amino and phenolic resins, polyhydric alcohols, acetal resins, paraformaldehyde, and fertilizers. It reacts with numerous organic compounds in condensation‐type reactions, resulting in formation of one or more new carbon‐carbon bonds. In recent years, formaldehyde has come under increased scrutiny because of its potential negative health effects. It is an irritant to the eyes, nose, and throat, and is a suspected human carcinogen.
Determining the conformation of surface species by DNP enhanced solid-state NMR (2014)

International audience
Postprandial Lipemic Response Is Modified by the Polymorphism at Codon 54 of the Fatty Acid–Binding Protein 2 Gene (1998)

Polymorphism of the fatty acid-binding protein 2 (FABP2) gene has been shown to affect the affinity of intestinal FABP for fatty acids. This could cause changes in postprandial triglyceride metabolism. In the present study, postprandial lipemia was studied in normotriglyceridemic subjects with genetic variation in the FABP2 gene. Oral fat-loading tests were performed in 8 subjects homozygous for the Thr-encoding allele at codon 54 of the FABP2 gene and in 7 subjects homozygous for the Ala-encoding allele (wild type). There were no significant differences between these 2 groups in age, body mass index, fasting plasma triglyceride and cholesterol levels, or fasting glucose and insulin levels. The increase of plasma triglyceride concentration after the fat test meal was significantly greater in subjects who were homozygous for the Thr-54 allele (area under the response curve, 4.27+/-1.31 versus 2.49+/-1.18 mmol/L x h-1, P=0.04). The difference was seen in both chylomicron (2.51+/-0. 98 versus 1.41+/-0.74 mmol/L x h-1, P=0.03) and very low-density lipoprotein triglycerides (1.57+/-0.77 versus 0.99+/-0.40 mmol/L x h-1, P=0.04). Postprandial triglyceride response correlated with fasting triglycerides in the Ala-54 homozygotes (r=0.79, P=0.05) but not in the Thr-54 homozygotes (r=0.09), who showed a strong correlation between triglyceride and insulin responses (r=0.83, P=0. 02). With reservations related to a small number of subjects studied, these results indicate that the Thr-encoding allele of the FABP2 gene is associated with increased postprandial lipemia. The lipemic response was associated with postprandial insulin response, suggesting that in the Thr-54 homozygotes, altered postprandial lipemia may also modify insulin action or vice versa.
應用於IEEE 802.11a之突波抑制頻率合成器 (2012)

In wireless communication systems, the local oscillator (LO) plays an important role. The oscillator used in a RF transceiver is usually embedded in a phase-locked loop (PLL) system so as to achieve a stable and precise definition of the output frequency, and this system is called “frequency synthesizer”. Synthesizer design still remains one of the most challenging issues in RF systems because it must meet very stringent requirements such as: settling time, phase noise, reference spur, etc. To reach an appropriate compromise among these requirements, we have proposed a new architecture adopting the high-resolution phase error calibration circuits and automatic frequency control (AFC) circuits to achieve a fast locking, wide range, and low reference spur PLL. To satisfy the IEEE 802.11a WLAN standards in the 5 GHz bands, a dual-band PLL-based frequency synthesizer is designed and fabricated in TSMC 0.18-μm CMOS technology. The chip size is 0.92 mm × 0.83 mm. At 5.76 GHz, the measured output spur level is less than -63 dBc after the high-resolution phase error calibration circuits are active. Throughout the whole output frequency range, the measured reference spurs are suppressed by 5.6-6.7 dB with calibration. The synthesizer draws 16 mA from a 1.8-V power supply, and the measured phase noise is -104 dBc/Hz at an offset frequency of 1 MHz.