gebhart/patrepeval huggingface dataset:
Size-controllable APTS stabilized ruthenium(0)nanoparticlescatalyst for the dehydrogenation of dimethylamine–borane at room temperature (2011)

Dimethylamine-borane, (CH(3))(2)NHBH(3), has been considered as one of the attractive materials for the efficient storage of hydrogen, which is still one of the key issues in the "Hydrogen Economy". In a recent communication we have reported the synthesis and characterization of 3-aminopropyltriethoxysilane stabilized ruthenium(0) nanoparticles with the preliminary results for their catalytic performance in the dehydrogenation of dimethylamine-borane at room temperature. Herein, we report a complete work including (i) effect of initial [APTS]/[Ru] molar ratio on both the size and the catalytic activity of ruthenium(0) nanoparticles, (ii) collection of extensive kinetic data under non-MTL conditions depending on the substrate and catalyst concentrations to define the rate law of Ru(0)/APTS-catalyzed dehydrogenation of dimethylamine-borane at room temperature, (iii) determination of activation parameters (E(a), ΔH(#) and ΔS(#)) for Ru(0)/APTS-catalyzed dehydrogenation of dimethylamine-borane; (iv) demonstration of the catalytic lifetime of Ru(0)/APTS nanoparticles in the dehydrogenation of dimethylamine-borane at room temperature, (v) testing the bottlability and reusability of Ru(0)/APTS nanocatalyst in the room-temperature dehydrogenation of dimethylamine-borane, (vi) quantitative carbon disulfide (CS(2)) poisoning experiments to find a corrected TTO and TOF values on a per-active-ruthenium-atom basis, (vii) a summary of extensive literature review for the catalysts tested in the catalytic dehydrogenation of dimethylamine-borane as part of the results and discussions.
Quantitative Analyses of SHG Endomicroscopy Images of Cervical Collagen Network for Detecting Preterm Birth in Mouse Models (2018)

SHG endomicroscopy imaging performed on cervical collagen is described. Subsequent image analyses quantify the morphological differences between normal and preterm pregnancy mice cervical tissue images.
Maturation enhances fluid shear-induced activation of eNOS in perfused ovine carotid arteries (2005)

The present study tests the hypothesis that age-dependent increases in endothelial vasodilator capacity are due to maturational increases in endothelial nitric oxide (NO) synthesis and release. Intact 4-cm carotid artery segments taken from term fetal lambs and nonpregnant adult sheep were perfused by using a closed system that enabled independent control of flow and inflow pressure and facilitated complete recovery of all NO released. Fluid shear stress induced a graded release of NO (in nmol NO x min x cm(-2) of luminal surface area) that was significantly greater in adult (890 +/- 140) than in fetal (300 +/- 40) carotid arteries at corresponding values of shear stress (5.9 +/- 0.3 dyn/cm2) but was independent of inflow pressure in both age groups. These age-related differences in NO release were not attributable to corresponding differences in endothelial NO synthase (eNOS) abundance, as eNOS protein levels (in ng of eNOS/cm2 of luminal surface area) were similar in adult (14 +/- 2) and fetal (12 +/- 1) arteries. Adult (80 +/- 15) and fetal (89 +/- 32) levels of eNOS mRNA (in 10(6) copies/cm2 of luminal surface area) were also similar. However, when NO release was normalized relative to the associated mass of eNOS protein to estimate eNOS-specific activity in situ, this value (in nmol NO x microg of eNOS(-1) x min(-1)) was significantly greater in adult (177 +/- 44) than in fetal (97 +/- 36) arteries when the endothelium was maximally activated by A-23187. Similarly, the slope of the relation between fluid shear stress and estimated eNOS-specific activity (in nmol NO x microg of eNOS(-1) x min(-1) per dyn/cm2) was also significantly greater in adult (6.8 +/- 0.1) than in fetal (2.9 +/- 0.1) arteries, which suggests that eNOS may be more sensitive to or more efficiently coupled to activating stimuli in adult compared with fetal arteries. We conclude that maturational increases in endothelial vasodilator capacity are attributable to age-dependent increases in NO release secondary to elevated eNOS-specific activity and involve more efficient coupling between endothelial activation and enhancement of eNOS activity in adult compared with fetal arteries.
On the Processes of the Charge Transfer in the Electrical Conducting Polymer Materials (2013)

The analysis of charge transfer processes in the electrical conducting solid polymer systems has been carried out. The processes in these systems are divided to two types. The first type is the process of charge transfer between electrodes and particles while the second onethe process of the charge transfer between conductive particles. The description of medium is carried out using Green temperature functions of polarization operators for the molecular medium. It permits taking into account the effects of frequency and space dispersion. The analytical expressions for kinetic parameters of the charge transfer processes from electrodes to particles and between particles in condensed matter have been obtained. The comparison of the general theoretical dependence of the current in electric conducting polymer composites (ECPC) on the average distance between conducting particles with analogical dependence for some real ECPC are presented in the paper.
ChemInform Abstract: REAGENTS AND SYNTHETIC METHODS. 14. A FACILE SYNTHESIS OF CARBOXYLIC ACID BROMIDES AND ESTERS UNDER NEUTRAL CONDITIONS VIA REACTION OF THE TRIMETHYLSILYL ESTERS WITH TRIPHENYLPHOSPHINE DIBROMIDE (1983)

Abstract Carbonsäuren (I) werden durch Umsetzung mit Triphenylphosphin‐dibromid (II) direkt oder über ihre Silylester (IV) rasch und schonend in Säurebromide (III) übergeführt.
Supervised class-specific dictionary learning for image classification (2016)

The employed dictionary plays a vital role in sparse representation based classification (SRC). Dictionary learning (DL) for classification proposed in previous work learns a dictionary by utilizing the original training samples and has shown satisfying classification accuracy when performing image classification. This paper proposes a novel supervised dictionary learning framework for classification, called supervised class-specific dictionary learning (SCDL), in which a class-specific dictionary (i.e., the atoms in the dictionary have relations with class labels) is learnt by using training samples with class labels. With this learnt dictionary, as well as the representation residual, the representation coefficients are also discriminative. And we then present a classification scheme corresponding to this SCDL model by utilizing these two discriminative cues. Experimental results have validated that the proposed SCDL obtains competitive classification accuracy compared with the existing state-of-the-art image classification methods.
HDAC-6 inhibition ameliorates the early neuropathology in a mouse model of Krabbe disease (2023)

Overall, our results support that ACY-738 has a neuroprotective effect in KD and should be considered as an add-on therapy combined with strategies targeting metabolic correction.
Electrical transport properties of Si-doped hexagonal boron nitride epilayers (2013)

The suitability of Si as an n-type dopant in hexagonal boron nitride (hBN) wide bandgap semiconductor has been investigated. Si doped hBN epilayers were grown via in-situ Si doping by metal organic chemical vapor deposition technique. Hall effect measurements revealed that Si doped hBN epilayers exhibit n-type conduction at high temperatures (T &amp;gt; 800 K) with an in-plane resistivity of ∼12 Ω·cm, electron mobility of μ ∼ 48 cm2/V·s and concentration of n ∼ 1 × 1016 cm−3. Temperature dependent resistivity results yielded a Si energy level in hBN of about 1.2 eV, which is consistent with a previously calculated value for Si substitutionally incorporated into the B sites in hBN. The results therefore indicate that Si is not a suitable dopant for hBN for room temperature device applications.
Effective learning strategies for real‐time image‐guided adaptive control of multiple‐source hyperthermia applicators (2010)

Based on the analysis presented herein, obtaining a unique global optimal heating vector for a multiple-source applicator within the constraints of real-time clinical hyperthermia treatments and thermal ablative therapies appears attainable using partial reconstruction with minimum norm least-squares method with supplemental equations. One way to supplement equations is the inclusion of a method of model reduction.
Genetic Variation in Sodium-Dependent Vitamin C TransportersSLC23A1andSLC23A2and Risk of Advanced Colorectal Adenoma (2008)

Previous observational studies suggest that vitamin C may reduce risk of colorectal cancer. Vitamin C transport is facilitated by membrane bound sodium-dependent transporters, SVCT1 (encoded by SLC23A1) and SVCT2 (encoded by SLC23A2). To investigate if common genetic variants in these two genes are associated with risk of colorectal tumor development, we conducted a case-control study of 656 Caucasian advanced distal colorectal adenoma cases and 665 Caucasian sigmoidoscopy-negative controls nested within the screening arm of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. The analysis of common single nucleotide polymorphisms in SLC23A1 revealed no association. For SLC23A2, overall, there was no association with haplotypes, but two SNPs located in intron 8 and exon 11 could be associated (odds ratio = 0.49, 95% confidence interval = 0.25-0.95 for haplotype G-C vs. haplotype C-C). The findings should be confirmed in follow-up studies, and further investigation is required to probe the functional basis of this finding.
Evaluating the Service Life of Thermoplastic Pavement Markings: Stochastic Approach (2018)

The study applied the Markov chain (MC) model that uses a transition matrix to transmit the probability of monitored pavement markings being in one service life state then changing into another service life state over a time interval. The service life prediction by MC models were then compared with those from linear models, testing if there were any clear advantages of using one model over the other in terms of predicting longevity of the marking retroreflectivity. The retroreflectivity data were collected by monitoring the coefficient of dry retroreflective luminance for 2 years using a handheld retroreflectometer. Using the MC model, the study found that the pavement marking retroreflectivity (PMR) degradation follows an exponential curve trend whereby the degradation rates decrease as the time increases. Significant differences were found in the deterioration of the markings based on the colors (white or yellow) and line type (center, lane line, or edge line). White thermoplastic edge lines on two-lane roadways were found to have a better performance (low deterioration rates) compared with the same lines on four-lane highways. Based on the transition probability matrix (TPM), it was observed that retroreflectivity is in an excellent or good state for a short period of time (54% probability) but is in a fair or poor state for a longer time (92% probability), suggesting the trend has a higher degradation rate at the beginning and a lower rate near the failure state. Keeping the minimum failure states at 150 and 100 mcd/m2/lx for white and yellow markings, respectively, the service life of white markings was found to be approximately 4 years (49.5 months) and it was found to be about 2.4 years (29 months) for yellow markings. The MC model findings were compared with those obtained through linear regression, which showed that white thermoplastic pavement markings take approximately 3.5 years (42 months) to deteriorate to failure state level, while yellow thermoplastics take about 2.1 years (25 months). The study concluded that there is a clear difference between the prediction using MC models compared with linear models, with MC models being more cost effective in terms of maintenance and replacement scheduling due to a longer life prediction.
Preparation and optimization of chlorophene-loaded nanospheres as controlled release antimicrobial delivery systems (2014)

Chlorophene-loaded nanospheres with various formulation parameters were evaluated. The optimal formulation was found at 0.1% w/v of poloxamer 407, 15 mL of ethyl acetate and 20% initial chlorophene loading that provided the suitable size (179 nm), the highest loading content (19.2%), encapsulation efficiency (88.0%) and yield (91.6%). Moreover, encapsulation of chlorophene in nanospheres was able to prolong and sustain drug release over one month. Chlorophene-loaded nanospheres were effective against Staphylococcus aureus (S. aureus) and Candida albicans (C. albicans), the main cause of hospital-acquired infections. Chlorophene-loaded nanospheres were effective against S. aureus (>46 µg/mL) and C. albicans (>184 µg/mL). These nanospheres appeared to have profound effect on the time-dependent hemolytic activity due to gradual release of chlorophene. At the concentration of 46 µg/mL, nearly no HRBC hemolysis in 24 h compared to 80% of hemolysis from free drug. In conclusion, polymeric nanospheres were successfully fabricated to encapsulate chlorophene which can eliminate inherent toxicity of drugs and have potential uses in prolonged release of antimicrobial.
Integrity Risk-Based Model Predictive Control for Mobile Robots (2019)

This paper presents a Model Predictive Controller (MPC) that uses navigation integrity risk as a constraint. Navigation integrity risk accounts for the presence of faults in localization sensors and algorithms, an increasingly important consideration as the number of robots operating in life and mission-critical situations is expected to increase dramatically in near future (e.g. a potential influx of self-driving cars). Specifically, the work uses a local nearest neighbor integrity risk evaluation methodology that accounts for data association faults as a constraint in order to guarantee localization safety over a receding horizon. Moreover, state and control-input constraints have also been enforced in this work. The proposed MPC design is tested using real-world mapped environments, showing that a robot is capable of maintaining a predefined minimum level of localization safety while operating in an urban environment.
Properties of Metalorganic Precursors for Chemical Vapor Deposition of Oxide Superconductors (1990)

In an attempt to improve the reproducibility of chemical vapor deposition of YBaCuO films from metalorganic compounds, we have investigated some properties of several metal β-diketonates by means of thermogravimetric analysis and mass spectroscopy. The results suggest that Ba-compounds should be vaporized under a reduced pressure of as low as 1 Torr. The vaporizing temperature becomes 180°C, being separated from the decomposition temperature of 250°C. Mass spectra of several metal β-diketonates have been obtained for the first time by paying much attention to the vaporizing temperature and ionization voltage.
Autophagy induction by histone deacetylase inhibitors inhibits HIV type 1. - eScholarship (2015)

Histone deacetylase inhibitors (HDACi) are being evaluated in a shock-and-kill therapeutic approach to reverse human immunodeficiency virus type-1 (HIV) latency from CD4(+) T cells. Using this approach, HDACi have induced HIV RNA synthesis in latently infected cells from some patients. The hope is that the increase in viral production will lead to killing of the infected cell either by the virus itself or by the patient's immune system, a sterilizing cure. Although administered within the context of combination antiretroviral therapy, the infection of bystander cells remains a concern. In this study, we investigated the effect of HDACi (belinostat, givinostat, panobinostat, romidepsin, and vorinostat) on the productive infection of macrophages. We demonstrate that the HDACi tested do not alter the initial susceptibility of macrophages to HIV infection. However, we demonstrate that HDACi decrease HIV release from macrophages in a dose-dependent manner (belinostat < givinostat < vorinostat < panobinostat < romidepsin) via degradation of intracellular HIV through the canonical autophagy pathway. This mechanism involves unc-51-like autophagy-activating kinase 1 (ULK1) and the inhibition of the mammalian target of rapamycin and requires the formation of autophagosomes and their maturation into autolysosomes in the absence of increased cell death. These data provide further evidence in support of a role for autophagy in the control of HIV infection and suggest that careful consideration of off-target effects will be essential if HDACi are to be a component of a multipronged approach to eliminate latently infected cells.
DCS Tx filters using AlN resonators with iridium electrodes (2010)

In this paper we present the design, fabrication technology, and characterization of BAW filters for the Digital Cellular System (DCS) Tx-band at 1.75 GHz. The filters are fabricated with AlN-based solidly mounted resonators (SMR) using iridium electrodes, in an attempt to increase the effective electromechanical coupling factor of the BAW devices and achieve the bandwidth requirements of DCS filters. The design and optimization of the filters is performed with a simulation tool that uses a circuit model to compute the filter frequency response. Tx filters with balanced inputs and outputs and different topologies are designed and fabricated. The experimental filter response is compared with the simulations to determine the suitability of each design. DCS bandwidth requirements are fulfilled by using Ir/AlN/Ir stacks.
Complete Chloroplast Genome Sequence of a Black Spruce (Picea mariana) from Eastern Canada (2020)

Here, we present the chloroplast genome sequence of black spruce (<i>Picea mariana</i>), a conifer widely distributed throughout North American boreal forests. This complete and annotated chloroplast sequence is 123,961 bp long and will contribute to future studies on the genetic basis of evolutionary change in spruce and adaptation in conifers.
A Proposal on the New Genotyping of Sacbrood viruses for the Definition of korean Sacbrood Virus (kSBV) (2017)

한국형 낭충봉아부패병 바이러스는 2009년 국내에 발생하여, 현재 국내 토봉의 99% 이상을 소멸시킨 주요 원인으로 추정되고 있다. 본 연구는 보고된 낭충봉아부패병 바이러스(SBV) 32종의 전체 염기서열을 비교 분석하여, 2,100 염기 부근에 특징적인 결실들(deletions)을 발견하였으며, 이에 기반으로 SBV의 유전자형을 제안하게 되었다. 제안된 유전자형에 의한 분류에서, 각 SBV의 지역성 및 범지역성, 감염특성 등에 유관함을 볼 수 있었다. 아울러, 제안된 이 유전자형은, 검역과 이후의 침임에 대한 방호를 위하여, kSBV의 기원도 바로 암시하고 있음을 우리는 잘 인식하고 있다.
The Snap! toolkit : a model for pluggable monitoring (2000)

Thesis (S.M.)--Massachusetts Institute of Technology, School of Architecture and Planning. Program in Media Arts and Sciences, 2000.
Uncoupling of the recBC ATPase from DNase by DNA Crosslinked with Psoralen (1972)

Exonucleolytic cleavage of DNA by the recBC DNase is accompained by a DNA-dependent ATP hydrolysis that ceases when the DNA that has been digested to a limit. On the other hand, DNA that has been crosslinked by 4,5',8-trimethylpsoralen in the presence of 360-nm light remains an effective cofactor in the ATPase reaction, but is resistant to digestion by the enzyme. Psoralentreated DNA is degraded by pancreatic DNase, micrococcal nuclease, and Escherichia coli B restriction enzyme, but not by Neurospora crassa nuclease, suggesting that crosslinking did not grossly distort the duplex structure of the DNA. The psoralen-DNA is not a potent inhibitor, but competes with single-stranded DNA from bacteriophage fd for the recBC DNase to roughly the same extent as does normal duplex DNA. DNA treated with psoralen in the dark, exposed to 360-nm light in the absence of psoralen, or treated with the intercalating agents ethidium bromide, 9-aminoacridine, ICR-191, or actinomycin D, responds to the enzyme no differently from untreated DNA. However, DNA crosslinked with mitomycin C or nitrogen mustard behaves similarly to psoralen-treated DNA. The relationship of these findings to models for the function and control of the recBC ATPase and nuclease, and the advantages of psoralen as a DNA crosslinking agent, are discussed.
Analytical chemistry at the Games of the XXIIIrd Olympiad in Los Angeles, 1984. (1987)

The equipment, methods, logistics, and results of doping-control analyses for the 1984 Los Angeles Olympic Games are discussed in this article. Within 15 days, 1510 different urine specimens underwent 9440 screening analyses by a combination of gas chromatography, gas chromatography-mass spectrometry, "high-performance" liquid chromatography, and radioimmunoassay. These tests covered more than 200 different drugs and metabolites, including psychomotor stimulants, sympathomimetic amines, central nervous system stimulants, narcotic analgesics, and anabolic steroids. The results are summarized by class of drug. Less than 2% of the samples were found to contain a banned drug.
CDH Diagnosed at 2 to 12 Months of Age–Treatment and Results (1989)

A treatment program for late-diagnosed CDH included skin traction, arthrography, tenotomy of adductor and psoas tendons, and immobilization of the hips in the “frog leg” position with a plaster cast for 8–12 weeks, followed by an abduction frame until the acetabular dysplasia normalized. Follow-up of 40 children with nonteratological CDH performed 2–12 years after diagnosis revealed 38 normal hips and 2 patients with coxa magna, one of whom had intermittent hip pain.
Theoretical determination of the pressure dependence of the electronic and the optical properties of fccC60 (1992)

The electronic, optical, and structural properties of fcc ${\mathrm{C}}_{60}$ crystal are studied as a function of cell volume by means of first-principles local-density calculations. The calculated equilibrium volume, bulk modulus, and the pressure-versus-volume relation are in good agreement with experimental measurements. Changes in the band structure, density of states, bonding pattern, dielectric constant, and optical spectrum with pressure are analyzed and discussed. It is found that the band gap and the absorption threshold energy decrease with increasing pressure while the static dielectric constant increases with increasing pressure. The charge-density map shows that at a pressure of 13 GPa covalent bonding between C atoms in different ${\mathrm{C}}_{60}$ molecules may form and metallization of ${\mathrm{C}}_{60}$ at ultrahigh pressure is unlikely. These results are in line with some very recent experimental observations.
Increased NIH 3T3 fibroblast functions on cell culture dishes which mimic the nanometer fibers&nbsp;of natural tissues (2015)

Traditional flat tissue cell culture dishes have consisted of polystyrene treated with plasma gases for growing, subculturing, and studying cell behavior in vitro. However, increasingly it has been observed that mimicking natural tissue properties (such as chemistry, three-dimensional structure, mechanical properties, etc) in vitro can lead to a better correlation of in vitro to in vivo cellular functions. The following studies compared traditional NIH 3T3 fibroblasts' functions on XanoMatrix scaffolds to standard tissue culture polystyrene. Results found significantly greater fibroblast adhesion and proliferation on XanoMatrix cell culture dishes which mimic the nanoscale geometry of natural tissue fibers with true, tortuous fiber beds creating a robust, consistent, and versatile growth platform. In this manner, this study supports that cell culture dishes which mimic features of natural tissues should be continually studied for a wide range of applications in which mimicking natural cellular functions are important.