gebhart/patrepeval huggingface dataset:
Polarity-dependent memory switching and behavior of Ag dendrite in Ag-photodoped amorphous As2S3 films (1976)

High cyclical reproducibility in polarity-dependent switching and memory function was obtained. Switching and memory effect seem to occur when both electrodes (Mo and Ag) are bridged by Ag dendrite which originates as the result of Ag photodoping. The combination of Ag electrode and another kind of electrode material may be responsible for the polarity-dependent switching and memory by the help of appropriate voltage shapes. Behavior of Ag dendrite was observed in relation to the similar electrical characteristics in a modified device structure. No thermal effects may be contained in the functional processes. Temperature dependence and frequency characteristics of the device resistances are measured and found to support the existence of the Ag dendrite and its role in the function in the original device. Switching transients in addition to the durability show the availability of the device in the compatibility with the magnetic core memory.
Chip-integrated bias circuits for MMIC (1999)

The work that forms the basis of this report deals with bias circuits for MMIC amplifiers. The task was concentrated on bias for low noise amplifiers with pHEMT and MESFET, and power amplifiers ...
Ultra-wide band Spiral shaped small Antenna for the Biomedical Telemetry (2006)

In this paper, the ultra-wide band spiral shaped small antenna for the implantable micro systems is proposed. Among these implantable systems, the capsule endoscope system operates inside the human body. The human body tissues which have effects on the antenna propagation characteristics are considered. To transmit the diagnostic real-time image data of high resolution at high speed, the system with larger bandwidth is needed. Thus, the bandwidth enhancement of the antenna is needed. To encase the system in the capsule module and to obtain ultra-wide band characteristics, the small sized spiral antenna is designed. The proposed antenna has the bandwidth of 400-510 MHz for VSWR<2 and the fractional bandwidth of 24.1 %. The antenna has the omni-directional radiation pattern and the size of 10.5 mm in diameter and 3 mm in height. Therefore, it is apparent that the proposed antenna provides the ultra-wideband characteristics at the biomedical frequency band and can be utilized to the UWB systems for the biomedical telemetry.
Age-Dependent Influence of Intrinsic and Extrinsic Motivations on Construction Worker Performance (2020)

The increasing sophistication and complexity of construction technology have also increased workers' physical risk and psychological stress. This study examined the relationships between health risks, work motivation, and productivity as perceived by construction workers. A hypothetical model of worker perceptions, and the psychological factors influencing these perceptions, was developed. A total of 324 construction workers at a Japanese construction company participated in the study and were divided into two groups: younger (45 years of age and below) and older adults (46 years of age and above). Data were collected using a questionnaire. The differences between the age groups were analyzed with regard to their perceptions of health risks, motivation, work skills, and productivity. Both younger and older workers were affected by intrinsic motivations and extrinsic motivations, but the effect of these motivations on work performance differed depending on age. Higher health risks are anticipated to affect the work motivation and productivity perceptions of older workers. The proposed model and findings of this study contribute to understanding worker motivations and have important implications for labor management of construction projects. By addressing construction workers' intrinsic (e.g., interest) and extrinsic (e.g., reward) motivations, it is possible to sustainably improve project productivity.
Configurable isolation (2007)

High availability is an increasingly important requirement for enterprise systems, often valued more than performance. Systems designed for high availability typically use redundant hardware for error detection and continued uptime in the event of a failure. Chip multiprocessors with an abundance of identical resources like cores, cache and interconnection networks would appear to be ideal building blocks for implementing high availability solutions on chip. However, doing so poses significant challenges with respect to error containment and faulty component replacement. Increasing silicon and transient fault rates with future technology scaling exacerbate the problem. This paper proposes a novel, cost-effective, architecture for high availability systems built from future multi-core processors. We propose a new chip multiprocessor architecture that provides configurable isolation for fault containment and component retirement, based upon cost-effective modifications to commodity designs. The design is evaluated for a state-of-the-art industrial fault model and the proposed architecture is shown to provide effective fault isolation and graceful degradation even when the failure rate is high.
Elevated Skp2 Protein Expression in Human Prostate Cancer (2002)

The F-box protein Skp2 (Fbl1) is a positive regulator of G1-S transition and promotes ubiquitin-mediated proteolysis of the cyclin-dependent kinase inhibitor p27. Its overexpression has been implicated in cell transformation and oncogenesis in both in vitro and in vivo models. In this study, we investigated its role in human prostate cancer progression. Immunohistochemical analysis was performed on formalin-fixed paraffin sections of 622 radical prostatectomy specimens, 74 prostatic intraepithelial neoplasm specimens, as well as in 4 normal prostate organ donors assembled into tissue microarrays. We found that both luminal and basal epithelial cells in normal prostate had very low Skp2 levels, but Skp2 levels and labeling frequency increased dramatically in both premalignant lesions of prostatic intraepithelial neoplasm ( P = 0.0252) and in prostate cancer ( P = 0.0037). The Skp2 labeling frequency in cancer was positively correlated with preoperative serum prostate-specific antigen level ( P = 0.0499) and Gleason score ( P = 0.0002), whereas the Skp2 index was positively correlated with extraprostatic extension ( P = 0.0454), clinical stage ( P = 0.0170), as well as Gleason score ( P = 0.0002). Kaplan-Meier analysis revealed that a higher Skp2 labeling index (>10) was a significant predictor of shorter biochemical recurrence-free survival time after radical prostatectomy ( P < 0.0363, log-rank test). An inverse correlation of Skp2 was observed with both its biochemical target p27 expression in prostate cancer ( P = 0.0003) and with its putative negative regulator, the PTEN tumor suppressor protein ( P = 0.0444). These data suggest that induction of Skp2 may be causally linked with decreased levels of p27 in prostate cancer and implicate PTEN in the regulation of Skp2 expression in vivo , as previous tissue culture experiments have suggested.
Progressive coding of 3-D graphic models (1998)

Based on state-of-the-art graphic-simplification techniques and progressive image-coding schemes, we propose a new hierarchical three-dimensional graphic-compression scheme in this research. This scheme progressively compresses an arbitrary polygonal mesh into a single bitstream. Along the encoding process, every output bit contributes to the reduction of coding distortion, and the contribution of bits decreases according to their order of position in the bitstream. At the receiver end, the decoder can stop at any point while giving a reconstruction of the original model with the best rate-distortion tradeoff. A series of models of continuous varying resolution can thus be constructed from the single bitstream. This property, which is referred to as the embedding property since the coding of a coarser model is embedded in the coding of a finer model, can be widely used in robust error control, progressive transmission and display, level-of-detail control, etc. It is demonstrated by experiments that an acceptable quality level can be achieved at a compression ratio of 20 to 1 for several test graphic models.
The Relationship between Utterances and "Involvement" in Conversational Dialogue (2006)

The performance of a non-task-oriented conversational dialogue system greatly depends on whether it can generate high involvement during conversation with users. In this paper, we clarify the types of utterances concerning involvement in human-human conversational dialogue. First, we define Dialogue Acts(DAs) and Rhetorical Relations(RRs), and propose a method for measuring ``Involvement''. Next, we show that the inter-annotator agreement on these tag schemes is quite high. Finally, we investigate the relationship between DAs/RRs and Involvement. We found that affective utterances and cooperative utterances are significant to generate high involvement in conversational dialogue.
COUPLING OF FUNCTIONAL MOLECULES ONTO LIGNIN MODEL COMPOUND DIBENZODIOXOCIN (2009)

Laccase-mediated grafting of functional
molecules presents an eco-friendly
approach to functionalise lignocellulose
materials. In this study functional
molecules in the form of reactive
phenolic amines, hydrophobicity
enhancing fluorophenols and selected
wood preservatives were successfully
coupled onto lignin model compound dibenzodioxocin as demonstrated by
HPLC analysis. This work therefore
presents for the first time a model for
functionalizing lignocellulose using the
lignin model dibenzodioxocin
Primary Total Hip Arthroplasty for Legg-Calvé-Perthes Syndrome: 20 Year Follow-Up Study. (2018)

Our findings support the use of THA for the treatment of OA in patients with LCPS, bearing in mind the potentially lower survival rate at 20 years as compared those treated with THA for primary OA. Further studies are needed to identify the possible causes of the high rate of cortical hypertrophy seen in this patient population.Level of Evidence: IV Therapeutic.
Raman study of SrBi2Ta2O9thin films (1999)

Abstract Thin films of SrBi2Ta2O9 (SBT) were deposited on Si using Sol-Gel technique. The thicknesses of the films 200 nm (SBT2) and 400 nm (SBT4), respectively. SEM were studies showed most of the grains in the film are smaller than 0.1 μ. FTIR reflectivity measurements of the samples showed bands around 1260, 936(for SBT2), 955(for SBT4), 770, 600 cm−1. Micro Raman spectra shows bands corresponding to the SBT materials, but some frequency shifts and broadening were observed. Particularly, the band around 818 cm−1, which corresponds to a stretching of the TaO6 octahedron, was found to change from 785 to 827 cm−1. This change seems to be related to the Ta-O bond length.
Reversible Social Self-Sorting of Colloidal Cell-Mimics with Blue Light Switchable Proteins (2018)

Toward the bottom-up assembly of synthetic cells from molecular building blocks, it is an ongoing challenge to assemble micrometer sized compartments that host different processes into precise multicompartmental assemblies, also called prototissues. The difficulty lies in controlling interactions between different compartments dynamically both in space and time, as these interactions determine how they organize with respect to each other and how they work together. In this study, we have been able to control the self-assembly and social self-sorting of four different types of colloids, which we use as a model for synthetic cells, into two separate families with visible light. For this purpose we used two photoswitchable protein pairs (iLID/Nano and nHagHigh/pMagHigh) that both reversibly heterodimerize upon blue light exposure and dissociate from each other in the dark. These photoswitchable proteins provide noninvasive, dynamic, and reversible remote control under biocompatible conditions over the self-assembly process with unprecedented spatial and temporal precision. In addition, each protein pair brings together specifically two different types of colloids. The orthogonality of the two protein pairs enables social self-sorting of a four component mixture into two distinct families of colloidal aggregates with controlled arrangements. These results will ultimately pave the way for the bottom-up assembly of multicompartment synthetic prototissues of a higher complexity, enabling us to control precisely and dynamically the organization of different compartments in space and time.
MEMS-based arrays of micro ion traps for quantum simulation scaling. (2006)

In this late-start Tier I Seniors Council sponsored LDRD, we have designed, simulated, microfabricated, packaged, and tested ion traps to extend the current quantum simulation capabilities of macro-ion traps to tens of ions in one and two dimensions in monolithically microfabricated micrometer-scaled MEMS-based ion traps. Such traps are being microfabricated and packaged at Sandia's MESA facility in a unique tungsten MEMS process that has already made arrays of millions of micron-sized cylindrical ion traps for mass spectroscopy applications. We define and discuss the motivation for quantum simulation using the trapping of ions, show the results of efforts in designing, simulating, and microfabricating W based MEMS ion traps at Sandia's MESA facility, and describe is some detail our development of a custom based ion trap chip packaging technology that enables the implementation of these devices in quantum physics experiments.
The Use of Animal Models for Rheumatoid Arthritis (2007)

Rheumatoid arthritis (RA) is a description of classical symptoms that can be grouped together to be recognized as a common entity. However, the disease is more heterogeneous and is likely composed of many different, distinct diseases. This heterogeneity is of two types. First, the disease can be classified into several subtypes, and second, the underlying cause of each disease group may be attributable to different genetic and environmental factors, each contributing to a distinct disease phenotype. This is an important starting point when discussing animal models for RA. Thus, there is not one model for RA. There are, and must be, several different models with different symptoms and different pathogenic mechanisms, controlled by different genes.
Synthese von optisch aktiven und racemischen 3‐Alkyl‐tetrahydrofuranen (1972)

Abstract Es wird eine allgemeine Herstellungsmethode von 2‐Alkyl‐1,4‐butandiolen 3 und deren Umwandlung zu den entsprechenden 3‐Alkyl‐tetrahydrofuranen 6 beschrieben: Ausgangsprodukte sind die 2‐Alkyl‐allylalkohole 1 , deren Hydroformylierung in Gegenwart von Rhodium‐Katalysatoren praktisch isomerisierungsfrei verläuft. Die Darstellung von (+) (3S, 1′S)‐ und (−) (3R, 1′S)‐3‐(1′‐Methylpropyl)‐tetrahydrofuran 6 d erfolgt nach dem hier beschriebenen Verfahren; die optische Reinheit der beiden Diastereomeren 6 d wurde bestimmt.
Biliary neopterin for differentiation between liver allograft rejection and viral graft infection (1992)

Differential diagnosis between rejection and infection of a liver graft still represents a major problem. Rising concentrations of neopterin in serum or urine sensitively indicate rejection or infectious complications after renal, cardiac or bone marrow transplantation [3]. Neopterin has been shown to be even more sensitive when measured locally, e.g. in the pancreatic juice of patients after pancreas allotransplantation [1]. In the present study, we measured urinary and, for the first time, biliary neopterin concentrations in nine liver allograft recipients during the early post-transplant period.
Characterization of the SecB protein, a chaperone that facilitates protein secretion in Escherichia coli (2007)

NOTE: Text or symbols not renderable in plain ASCII are indicated by [...]. Abstract is included in .pdf document. It has become increasingly clear that in Escherichia coli, most exported proteins are translocated either posttranslationally or late in their synthesis, and that a component of the export apparatus, SecB, facilitates the export of a subset of the secreted proteins by maintaining them in an export-competent, unfolded form. In an effort to understand how SecB functions as an antifolding factor, we mapped and characterized the sites of SecB interaction in the outer membrane protein LamB. We found that the interaction of SecB with LamB was dependent on the LamB signal sequence as well as on a region in the mature LamB protein. The simplest interpretation of these findings is that SecB binds to both the LamB signal sequence and a mature region in LamB, and that this interaction promotes the antifolding activity of SecB. Given the fact that several heat-shock proteins have also been shown to function as antifolding factors, we wanted to investigate whether heat-shock proteins might act in a manner analogous to SecB in facilitating the export process. We found that induction of the heat-shock response could substitute for SecB function (SecB is not a heat-shock protein), and that a basal level of heat-shock proteins was necessary for the cell to survive in the absence of SecB protein. These results suggested that heat-shock proteins might indeed be involved in the secretory process and function in a manner similar to that of SecB. In an attempt to identify these proteins, suppressors of a secB null mutation were isolated and characterized. Not unexpectedly, most of these suppressors mapped to the rpoH locus. Since rpoH encodes [...], the heat-shock transcription factor, it is likely that these suppressors affect the synthesis levels of heat-shock proteins, which can substitute for SecB function. The remaining suppressors did not map to any known heat-shock or export genes, and potentially represent unidentified heat-shock proteins or export factors that act in a manner similar to SecB in facilitating the export process in E. coli.
Fabrication of an Anode‐Supported Gadolinium‐Doped Ceria Solid Oxide Fuel Cell and Its Operation at 550°C (2005)

Ce 0.9 Gd 0.1 O 2− x (CGO) layers were deposited onto nonconductive porous NiO–CGO supports by electrophoretic infiltration, and then compacted by isostatic pressing to achieve a high packing density of the deposited layer. The bilayers were sintered to give dense CGO layers at 1290°C in air. A fuel cell comprising an La 0.6 Sr 0.4 Co 0.2 Fe 0.8 O 3− x cathode, a 10‐μm CGO electrolyte, and a Ni–CGO anode was tested at 550°C with humidified 10% H 2 and air. The cell showed an open circuit voltage of 0.86 V and delivered a steady current of about 470 mA/cm 2 at a terminal voltage of 0.24 V.
Conformation and Aggregation of Selectively PEGylated and Lipidated Gastric Peptide Hormone Human PYY3–36 (2018)

The gastric peptide hormone human PYY<sub>3-36</sub> is a target for the development of therapeutics, especially for treatment of obesity. The conformation and aggregation behavior of PEGylated and lipidated derivatives of this peptide are examined using a combination of fluorescence dye assays, circular dichroism (CD) spectroscopy, analytical ultracentrifugation (AUC) measurements, small-angle X-ray scattering (SAXS) and cryogenic-transmission electron microscopy (cryo-TEM). The behavior of two PYY<sub>3-36</sub> derivatives lipidated (with octyl chains) in different positions is compared to that of two derivatives with PEG attached at different residues and to that of the native peptide. We find that, unexpectedly, PYY<sub>3-36</sub> forms amyloid fibril structures above a critical aggregation concentration. Formation of these structures is suppressed by PEGylation or lipidation. PEGylation significantly reduces the (reversible) loss of α-helix content observed on heating PYY<sub>3-36</sub>. The PEG conjugates form mainly monomeric structures in solution- coiled-coil formation, and other aggregation presumably being sterically hindered by swollen PEG chains. However, some small aggregates are detected by AUC. In complete contrast, both of the two lipidated peptides show the formation of spherical micelle-like structures which are small oligomeric aggregates. Our findings show that PEGylation and lipidation are complementary strategies to tune the conformation and aggregation of the important gastric peptide hormone human PYY<sub>3-36</sub>.
Supplementary material from "The Williams syndrome prosociality gene GTF2I mediates oxytocin reactivity and social anxiety in a healthy population" (2017)

The neurohormone oxytocin plays a central role in human social behaviour and cognition, and oxytocin dysregulation may contribute to psychiatric disorders. However, genetic factors influencing individual variation in the oxytocinergic system remain poorly understood. We genotyped 169 healthy adults for a functional polymorphism in GTF2I (<i>general transcription factor II-I</i>), a gene associated with high prosociality and reduced social anxiety in Williams syndrome, a condition reported to involve high oxytocin levels and reactivity. Participants’ salivary oxytocin levels were measured before and after watching a validated empathy-inducing video. Oxytocin reactivity, defined as pre- to post-video percentage change in salivary oxytocin, varied substantially and significantly between individuals with different GTF2I genotypes, with, additionally, a trend towards an interaction between genotype and sex. Individuals with more oxytocin-reactive genotypes also reported significantly lower social anxiety. These findings suggest a model whereby GTF2I has a continuum of effects on human sociality, from the extreme social phenotypes and oxytocin dysregulation associated with gene deletion in Williams syndrome, to individual differences in oxytocin reactivity and sociality associated with common polymorphisms in healthy populations.
Objective and Subjective Evaluation of Head-Related Transfer Function Filter Design (1999)

In this paper, the problem of modeling head-related transfer functions (HRTFs) is addressed. Traditionally, HRTFs are approximated in real-time applications using minimumphase reconstruction and various digital filter design techniques, yielding FIR or IIR structures. In this work, binaural auditory modeling has been applied to HRTF analysis and filter design methods have been compared from the auditory perception point of view. This paper presents applicable perceptually valid filter design techniques and discusses listening test results for localization and timbre degradation. 1 Introduction The rapidly growing field of 3-D audio is dependent on accurate and correctly reproduced binaural hearing cues. These cues are embodied in head-related transfer functions (HRTFs) that describe the free-field transmission to a point in the human ear canal [1, 2]. This work focuses on the desired accuracy of HRTF representations in binaural synthesis. Progress in research of filter design for 3...
An overview of automatic speaker recognition technology (2002)

In this paper we provide a brief overview of the area of speaker recognition, describing applications, underlying techniques and some indications of performance. Following this overview we will discuss some of the strengths and weaknesses of current speaker recognition technologies and outline some potential future trends in research, development and applications.