gebhart/patrepeval huggingface dataset:
Classification of Spectroscopically Encoded Resins by Raman Mapping and Infrared Hyperspectral Imaging (2006)

Barcoded resins (BCRs) were recently introduced as a potential platform for pre-encoded multiplexed synthesis, screening, and biomedical diagnostics. A key step toward the development of this strategy is the ability to rapidly interrogate and classify the BCRs in a high-throughput, noninvasive manner. Here, we describe a one-step strategy based on Raman mapping and Fourier transform infrared imaging to classify and spatially resolve randomly distributed BCRs. To illustrate this methodology, mixtures of up to 25 different BCRs were imaged and classified with 100% confidence. This strategy can be readily extended to a larger pool of resins, provided each BCR features a unique vibrational fingerprint (spectroscopic barcode). We have also established that reliable single-bead Raman spectra can be recorded in 10 ms, thus confirming that Raman mapping, in particular, could be a very fast method to classify the BCRs.
The Density and Surface Tension of Synthetic Turbine Engine Lubricants from 100 to 400F. (1972)

The report describes techniques for experimental determination of the density and surface tension of synthetic turbine engine lubrications over the temperature range 100-400 deg F. Density values are reported for 22 lubricants, and surface tension values for 19 lubricants. Least-squares analysis reveals how density and surface tension vary with temperature according to a general formula. Parameters are tabulated for each of the fluids studied. The significance of density and surface tension data for lubrication engineering is discussed. Examples are given in which lubricant behavior can be explained and understood in terms of these properties.
Fluid distribution effect on sonic attenuation in partially saturated limestones (1998)

Abstract Extensional and torsional wave-attenuation measurements are obtained at a sonic frequency around 1 kHz on partially saturated limestones using large resonant bars, 1 m long. To study the influence of the fluid distribution, we use two different saturation methods: drying and depressurization. When water saturation (Sw) is higher than 70%, the extensional wave attenuation is found to depend on whether the resonant bar is jacketed. This can be interpreted as the Biot-Gardner-White effect. The experimental results obtained on jacketed samples show that, during a drying experiment, extensional wave attenuation is influenced strongly by the fluid content when Sw is between approximately 60% and 100%. This sensitivity to fluid saturation vanishes when saturation is obtained through depressurization. Using a computer-assisted tomographic (CT) scan, we found that, during depressurization, the fluid distribution is homogeneous at the millimetric scale at all saturations. In contrast, during drying, heterogeneous saturation was observed at high water-saturation levels. Thus, we interpret the dependence of the extensional wave attenuation upon the saturation method as principally caused by a fluid distribution effect. Torsional attenuation shows no sensitivity to fluid saturation for Sw between 5% and 100%.
Effects of Nortriptyline on Heart Rate Variability in Panic Disorder Patients: A Preliminary Study Using Power Spectral Analysis of Heart Rate (1994)

Previous reports on heart rate variability suggest that, compared to controls, panic disorder patients have a higher relative mid-frequency (MF) (0.07-0.15 Hz) power in standing posture and that they also have a greater increase in standing MF power after the administration of yohimbine. We studied the effects of nortriptyline, a tricyclic antidepressant, on HR variability measures in 13 panic disorder patients before and after successful treatment. There was a highly significant increase in supine and standing HR (p = 0.00001) while there was a significant decrease of standing absolute and relative MF power (p = 0.009 and 0.0001 respectively). This uncontrolled preliminary study suggests a decrease in sympathetic activity related to nortriptyline treatment in addition to its anticholinergic effects.
ChemInform Abstract: Iron(II)‐1,2,4‐triazole Spin Transition Molecular Materials (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Gas contaminant effects in discharge-excited XeCl lasers (1991)

During the past decade, the number of excimer lasers used worldwide has steadily increased. The lasers have graduated from laboratory curiosities to production tools in industrial applications. Today, excimer laser users are becoming increasingly sensitive to operating costs and reliability. Gas lifetime is a key issue in achieving high performance and reduced operating costs.
Innovative Approaches to Verifying Demand Response of Water Heater Load Control (2005)

This study describes a pilot effort to measure load reductions from a residential electric water heater (EWH) load control program using low-cost statistically based measurement and verification (M&V) approaches. This field experiment is described within the larger framework of overcoming barriers to participation of noninterval metered customers in Demand Response (DR) Programs. We worked with PJM Interconnection and a Curtailment Service Provider (CSP) to collect hourly load data for two substations and several hundred households over six weeks of load control testing. The experimental design reflected constraints imposed by limited funding, manpower, equipment, and the routine operation of the load control system by the CSP. We analyzed substation- and premise-level data from these tests in an attempt to verify several "point estimates" taken from the hourly diversified demand curves used by the CSP to establish aggregate load reductions from their control program. Analysis of premise-level data allowed for provisional verification that the actual electric water heater load control impacts were within a -60 to +10% band of the estimated values. For sub-station level data, measured values of per-unit load impacts were generally lower than the CSP estimated values for Electric Cooperative #2, after accounting for confounding influences and operational test problems. Based on this experience we offer recommendations to ISO and utility DR program managers to consider before undertaking further development of alternatives to the conventional but costly program-wide load research approach.
Extended Particle Filter (EPF) for INS/GPS Land Vehicle Navigation Applications (2007)

Navigation comprises the integration of methodologies and systems for estimating the time varying position, velocity and attitude of moving objects. Navigation using integrated INS/GPS systems requires in general extensive evaluations of nonlinear equations involving double integration. Currently, integrated navigation systems are commonly implemented using Extended Kalman Filter (EKF) and most recently Unscented Kalman Filter (UKF). The EKF assumes linear process and measurement models while both the EKF and UKF approximate the noise models with Gaussian fits. This approximation is unrealistic for highly nonlinear systems, which is true for both EKF and UKF implementations. To overcome these limitations, Particle Filter (PF) was proposed lately since it is a non-parametric filter and hence it can easily deal with non-linearities and non-Gaussian noises. In this paper, an Extended Particle Filter (EPF) is developed as an alternative to the common EKF for land-vehicle navigation applications. Experimental GPS/INS datasets including dual frequency carrier phase GPS receiver data and inertial measurements from two different MEMSgrade Inertial Measuring Units (IMUs) installed on same vehicle are used to evaluate the proposed EPF technique. The performance of the developed EPF is compared to the performance of current estimation techniques such as the EKF. The comparison is the difference between the navigation errors of the two filters when GPS signals are available all the time and during GPS signal outages.
Hydrodehalogenation of alkyl halides catalyzed by a trichloroniobium complex with a redox active α-diimine ligand (2019)

A high-valent d<sup>0</sup> niobium(v) complex, (α-diimine)NbCl<sub>3</sub> (1), bearing a dianionic redox-active α-diimine ligand served as a catalyst for a hydrodehalogenation reaction of alkyl halides in the presence of PhSiH<sub>3</sub>. During the catalytic reaction, the redox-active α-diimine ligand allowed the complex to reversibly release and accept one-electron through switching its coordination mode between a dianionic folded form and a monoanionic planar one.
Poly‐cyclodextrin functionalized porous bioceramics for local chemotherapy and anticancer bone reconstruction (2013)

Abstract The progress in bone cancer surgery and multimodal treatment concept achieve only modest improvement in the overall survival, due to failure in clearing out residual cancer cells at the surgical margin and extreme side‐effects of adjuvant postoperative treatments. Our study aims to propose a new method based on cyclodextrin polymer (polyCD) functionalized hydroxyapatite (HA) for achieving a high local drug concentration with a sustained release profile and a better control of residual malignant cells via local drug delivery and promotion of the reconstruction of bone defects. PolyCD, a versatile carrier for therapeutic molecules, can be incorporated into HA (bone regeneration scaffold) through thermal treatment. The parameters of polyCD treatment on the macroporous HA (porosity 65%) were characterized via thermogravimetric analysis. Good cytocompatibility of polyCD functionalized bioceramics was demonstrated on osteoblast cells by cell vitality assay. An antibiotic (gentamicin) and an anticancer agent (cisplatin) were respectively loaded on polyCD functionalized bioceramics for drug release test. The results show that polyCD functionalization leads to significantly improved drug loading quantity (30% more concerning gentamicin and twice more for cisplatin) and drug release duration (7 days longer concerning gentamicin and 3 days longer for cisplatin). Conclusively, this study offers a safe and reliable drug delivery system for bioceramic matrices, which can load anticancer agents (or/and antibiotics) to reduce local recurrence (or/and infection). © 2014 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 102B: 1130–1139, 2014.
Investigation of non-negativity constraint on basis images in half-rotation data reconstruction in spectral CT (2016)

In conventional computed tomography (CT) reconstruction, a non-negativity constraint on the image values is often included. Such constraint reduces the feasible set in a constrained optimization problem and often results in faster search. In basis-material-based spectral CT reconstruction, the physical grounding for the non-negativity constraint of basis image values is no longer present. It is either not used [1] or relaxed to allow only small-magnitude negative values [2]. However, such constraint can still be applied as part of the decomposition model [3] and to reduce the feasible set and search space. We have developed an optimizationbased reconstruction method that integrates decomposition into reconstruction and allows for flexible spectral data acquisition [4], [5]. The non-negativity constraint was included in the previous reconstructions as it was part of the decomposition model for the phantom used. As we recently applied the method to half-plus-half rotation scans with a dual energy phantom containing iodine and calcium inserts, streak artifacts appeared in the images surrounding calcium inserts which also showed HU value biases. This has led us to re-evaluate the need for the non-negativity constraint in this particular problem and investigate its impact on the reconstruction in terms of visual comparison and bias evaluation.
Influence of Chamber Geometry and Operating Conditions on the Performance of Feedback-Free Fluidic Oscillators (2015)

The feedback free fluidic oscillator uses the unsteady nature of two colliding jets to create a single oscillating outlet jet with a wide sweep angle. These devices have the potential to provide additional combustion control, boundary layer control, thrust vectoring, and industrial flow deflection. The work presented in this paper uses two-dimensional computational fluid dynamics, CFD, to analyze the jet oscillation frequency over a range of operating conditions and to determine the effect that geometric changes in the oscillator design have on the frequency. In addition, microphone data gathered from six 3D printed fluidic oscillators is used to validate the CFD and correlate the 2D analysis to several different oscillator aspect ratios. Results presented in this paper illustrate the changes in jet oscillation frequency with gas type, gas temperature, operating pressure, pressure ratio across the oscillator, aspect ratio of the oscillator, and the frequency trends with various changes to the oscillator g...
Determination of glucuronic acid in serum by HPLC. (1998)

血清中のグルクロン酸をイオン対法を用いてHPLCで精度よく測定するための条件を種々検討し,最適分析条件を確立した.血清200μlを硫酸で酸分解し水酸化ナトリウムで中和した.更に3-メチル-1-フェニル-5-ピラゾロン(PMP)-メタノール溶液と水酸化ナトリウムを加えてPMP化した.次に硫酸で中和後,未反応試薬をクロロホルムで除去し,その水相の一定量をHPLC分析用試料とした.イオン対法を用いたことで,グルクロン酸と血液中に含まれるグルコースを分離することが可能となった.本法の検量線は5～50mg/lの範囲で直線性を示し,回収率は82～94%,相対標準偏差は日内変動で0.6～4.9%,日間変動で4.9～7.2%と良好であった.更に-20℃で30日間安定,2回の凍結・解凍にも安定であることが確認された.
Becoming Teacher Researchers One Moment at a Time (1999)

Power and Hubbard draw on the voices of teachers to offer a glimpse into the process of becoming teacher researchers.
Experiment on operating methods of an electric wheelchair for a system of detecting position and direction (2007)

In this paper, we propose a voice-controlled electric wheelchair with a system for detecting the position and direction. Thus far, we have studied systems that incorporated voice instructions with our indoor navigation equipment using RF tags. An operating method which is different in order to clarify the problem of the operation method of an existing wheelchair was measured in the same environment. We then evaluated the results from the viewpoint of the usability of each operation in order to determine the most suitable assisting operation. We found that it is very effective to memorize one of the possible stopping positions and the angles of rotations to desired directions, which could adequately assist the movement of a wheelchair.
X‐ray Scattering from Films of Semiconducting Polymers (2008)

A review of recent studies of X‐ray scattering from films of semiconducting polymers is presented with an emphasis on materials used for thin film transistors. Common types of scattering experiments are described with a focus on synchrotron X‐ray sources. The basic molecular packing structure and microstructural features of polycrystalline thin films of polythiophenes and polyfluorenes are described. The influence of processing conditions, such as thermal annealing, on the microstructure of these materials is outlined and example studies on polythiophenes are presented in detail. The microstructures of blends of these polymers and their co‐polymers are also discussed
Observing Clonal Dynamics across Spatiotemporal Axes: A Prelude to Quantitative Fitness Models for Cancer (2017)

The ability to accurately model evolutionary dynamics in cancer would allow for prediction of progression and response to therapy. As a prelude to quantitative understanding of evolutionary dynamics, researchers must gather observations of in vivo tumor evolution. High-throughput genome sequencing now provides the means to profile the mutational content of evolving tumor clones from patient biopsies. Together with the development of models of tumor evolution, reconstructing evolutionary histories of individual tumors generates hypotheses about the dynamics of evolution that produced the observed clones. In this review, we provide a brief overview of the concepts involved in predicting evolutionary histories, and provide a workflow based on bulk and targeted-genome sequencing. We then describe the application of this workflow to time series data obtained for transformed and progressed follicular lymphomas (FL), and contrast the observed evolutionary dynamics between these two subtypes. We next describe results from a spatial sampling study of high-grade serous (HGS) ovarian cancer, propose mechanisms of disease spread based on the observed clonal mixtures, and provide examples of diversification through subclonal acquisition of driver mutations and convergent evolution. Finally, we state implications of the techniques discussed in this review as a necessary but insufficient step on the path to predictive modelling of disease dynamics.
Vibration absorber for reduction of the in-plane vibration in an optical disk drive (2004)

A new type of vibration absorber is developed to reduce the in-plane vibration of the feeding deck system in an optical disk drive. In order to derive the equations of motion for the feeding deck system with the absorbers, a vibration model is established. After the frequency response function is obtained from the equations, the effects of absorber mass, stiffness and damping are analyzed. The material properties and shape of the vibration absorber are determined from the analysis results. For the purpose of verification, the performance of the absorber is investigated through experiments. The test results show that the proposed absorber is able to considerably reduce vibration in a wide range of spindle motor speeds.
Impact of aerodynamic modelling on seakeeping performance of a floating vertical axis wind turbine (2019)

Abstract This study focuses on the impact of the aerodynamic model on the dynamic response of a floating vertical axis wind turbine (VAWT). It compares a state‐of‐the‐art quasi‐steady double multiple streamtube (DMS) solver, a prescribed vortex wake (PVW), and a free vortex wake (FVW) solver. The aerodynamic loads acting on a bottom‐fixed VAWT and computed with the three aerodynamic solvers are compared, then the dynamic responses of the floating turbine in irregular waves and turbulent wind with the different aerodynamic solvers are compared. Differences are observed, particularly in the mean motions of the platform. Eventually, the aerodynamic damping computed by the solvers are estimated with aerodynamic simulations on the turbine with imposed surge and pitch motions. The estimated damping can then be correlated with the dynamic response amplitude of the VAWT. Substantial discrepancies are observed between the three solvers at high tip speed ratio, when the rotor is highly loaded. It is shown that the quasi‐steady DMS solver seems to give greater amplitude of motions for the floating VAWT because of strong rotor/wake interaction that are not correctly accounted for.
Mechanisms underlying the potential usefulness of the herbal preparation STW 5 in an experimental model of Crohn's disease (2016)

The herbal preparation STW 5 is a standardized multi-component mixture of hydro-alcoholic extracts of bitter candytuft, lemon balm, chamomile, caraway fruit, peppermint leaf, Angelica root, milk thistle, celandine herb, and licorice root. It has been used successfully clinically in functional dyspepsia [1] and irritable bowel syndrome [2]. We have reported earlier on its efficacy in experimental dextran sodium sulfate induced colitis as a model for ulcerative colitis [3]. The present study was conducted to investigate underlying mechanisms involved in its use in 2,4,6-trinitrobenzene sulfonic acid (TNBS) induced colitis as a model of Crohn's disease. Colitis was induced by instilling TNBS in the colon of male Wistar rats under light ether anesthesia. In a prophylactic setting STW 5 was given orally for 1 week before induction of colitis and continued for 3 days after. In a curative setting, STW 5 was given 48h after colitis induction daily orally for 1 week. Rats were sacrificed 24h after last treatment. Colonic tissue was assessed macroscopically while homogenates and serum samples were used to assess inflammatory and oxidative stress parameters. TNBS colitis led to severe ulcerative damage, inhibition of reduced glutathione and a rise in myeloperoxidase in colon homogenates. Relevant cytokines TNFα, IL-1β, ICAM-1 were elevated as well as LT-B4 and PGE2. Immuno-histochemical examination of colon sections showed a rise in calprotectin and IL-17A staining, both of which are reported to be relevant indicators for IBD in man. Pre-treatment with STW 5 reversed such effects in a comparable manner to sulfasalazine. In the curative setting, the preparation tended to normalize changes in reduced glutathione and myeloperoxidase and in ulcerative indices induced by TNBS. The findings lend good supportive evidence for the potential usefulness of STW 5 in Crohn's disease.
What's UP 3.0 : spontaneous social networking in challenged networks (2009)

International audience
Design of Nanohybrids from Well Defined NanoBuilding Blocks (2006)

Titanium-oxo clusters are employed as inorganic nanobuilding blocks in order to obtain new organic-inorganic hybrid materials. Nanobuilding blocks are well-defined preformed entities which allow a better control of the inorganic domains for the elaboration of hybrid nanocomposites. The oxo-alcoxo cluster Ti16O16(OEt)32 presents a shell of labile ethoxy groups which can be selectively exchanged with preservation of the oxo-core. Both the kinetics of the solvolysis and the number of substituted titanium atoms are strongly dependent on the nature of the reactants. The post-modification of the cluster lead to the elaboration of new oxo-alcoxo clusters Ti16O16(OEt)32- x(OR)x (R : alkyl, phenyl… groups) and when polymerizable ligands, such as methacrylate or styrenic ligands, are introduced at the surface of the nanobrick, new functional nanobuilding blocks can be obtained. These functional clusters are then copolymerized with organic monomers leading to 3D networks where the inorganic nano-fillers are covalently linked to the organic polymer and act as very effective nano-cross-linker. These nanobricks can be considered as good models to correlate the structure of hybrid materials and their physical properties especially their mechanical, thermal, and optical properties.
Bluetooth smart: An enabling technology for the Internet of Things (2015)

The past couple of years have seen a heightened interest in the Internet of Things (IoT), transcending industry, academia and government. As with new ideas that hold immense potential, the optimism of IoT has also exaggerated the underlying technologies well before they can mature into a sustainable ecosystem. While 6LoWPAN has emerged as a disruptive technology that brings IP capability to networks of resource constrained devices, a suitable radio technology for this device class is still debatable. In the recent past, Bluetooth Low Energy (LE) — a subset of the Bluetooth v4.0 stack — has surfaced as an appealing alternative that provides a low-power and loosely coupled mechanism for sensor data collection with ubiquitous units (e.g., smartphones and tablets). When Bluetooth 4.0 was first released, it was not targeted for IP-connected devices but for communication between two neighboring peers. However, the latest release of Bluetooth 4.2 offers features that makes Bluetooth LE a competitive candidate among the available low-power communication technologies in the IoT space. In this paper, we discuss the novel features of Bluetooth LE and its applicability in 6LoWPAN networks. We also highlight important research questions and pointers for potential improvement for its greater impact.