gebhart/patrepeval huggingface dataset:
A method for identification of overlapping single echoes: application to NDE tests (2003)

A method is proposed for identifying single echoes in a multiple echo which is the sum of overlapping similar echoes. The final aim is to give for each single echo two pertinent items of information: the weighting factor and the time-delay estimate. The model developed is based on the computation of the complex envelope which is derived from the analytic signal associated with the received signal. The model uses information regarding both amplitude and phase variations with regards to time. Experimental signals obtained during NDE tests of a metallic block with artificial defects are used to verify the theoretical model. The results show good agreement with theory.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Application of Multifractal Analysis on Medical Images (2008)

This paper shows results of computer analysis of images in the purpose of finding differences between medical images in order of their classifications in terms of separation malign tissue from normal and benign tissue. The diagnostics of malign tissue is of the crucial importance in medicine. Therefore, ascertainment of the correlation between multifractals parameters and chaotic cells could be of the great appliance. This paper shows the application of multifractal analysis for additional help in cancer diagnosis, as well as diminishing. of the subjective factor and error probability.
Cell stiffness under small and large deformations measured by optical tweezers and atomic force microscopy: effects of actin disruptors CK-869 and jasplakinolide (2020)

Abstract Cytoskeleton-disrupting drugs can have different effects on cell mechanics at different deformation scales. We therefore applied two complementary indentation techniques to study the effects of two actin-disrupting drugs on cellular stiffness of human umbilical vein endothelial cells. Optical tweezers were used to probe the cortical stiffness at small deformations, and atomic force microscopy was used to probe the bulk cell stiffness at larger deformations. The first drug studied was CK-869, which is an inhibitor of the actin branching complex Arp2/3, and has not been analysed yet in terms of mechanical effects. A significant decrease in cell stiffness upon treatment with CK-869 was measured with both techniques, which implies that actin branching is important for cell mechanics at small and large deformations. The second drug studied was jasplakinolide, for which ambiguous effects on cell mechanics have been reported. In line with previous studies, we found that jasplakinolide caused significant cell stiffening at large deformations but slight cell softening under small deformations. This result implies that jasplakinolide has different effects on different levels of actin organization.
Asynchronous waveform generating device for use in an electronic musical instrument (1994)

First Page
Estimation for Models Defined by Conditions on Their L-Moments (2016)

This paper extends the empirical minimum divergence approach for models, which satisfy linear constraints with respect to the probability measure of the underlying variable (moment constraints) to the case where such constraints pertain to its quantile measure (called here semiparametric quantile models). The case when these constraints describe shape conditions as handled by the L-moments is considered, and both the description of these models as well as the resulting nonclassical minimum divergence procedures are presented. These models describe neighbourhoods of classical models used mainly for their tail behavior, for example, neighborhoods of Pareto or Weibull distributions, with which they may share the same first L-moments. The properties of the resulting estimators are illustrated by simulated examples comparing maximum likelihood estimators on Pareto and Weibull models to the minimum chi-square empirical divergence approach on semiparametric quantile models, and others.
Debugging sequential circuits using Boolean satisfiability (2005)

Logic debugging of today's complex sequential circuits is an important problem. In this paper, a logic debugging methodology for multiple errors in sequential circuits with no state equivalence is developed. The proposed approach reduces the problem of debugging to an instance of Boolean satisfiability. This formulation takes advantage of modern Boolean satisfiability solvers that handle large circuits in a computationally efficient manner. An extensive suite of experiments with large sequential circuits confirm the robustness and efficiency of the proposed approach. The results further suggest that Boolean satisfiability provides an effective platform for sequential logic debugging.
Hot Tearing in Al-Mg-Si Alloys with Minor Additions of Cu or Mn (2011)

A study of the influence of minor additions of copper or manganese on hot tear susceptibility in Al-Mg-Si alloys has been conducted. Testing was carried out using a laboratory scale hot tearing rig and the results were validated using an analysis of cast house cracking scrap data for 6060 and 6063 extrusion billet alloys. Mn content was found to have a strong influence on hot tearing rates.
A case of duplication of the stomach found at the pre-operative ultrasound examination. (1990)

42歳女性で超音波検査により発見された胃重複症の1例を経験したので報告する.超音波検査, computed tom Ography (以下CT) 検査で肝左葉下方, 胃小弯側に接して境界明瞭な球状の嚢胞を認めた.上部消化管造影, 胃内視鏡検査では噴門部小弯に3×3cmの表面平滑でなだらかな隆起があり, 胃壁外性腫瘤で胃内腔との交通はなかった.手術所見では腫瘤は胃壁小弯と連続しており, 胃壁を一部含めて摘出した.摘出標本では径4cmの嚢胞で膿汁様液が充満していた.病理組織学的には粘膜, 筋層, 衆膜の層構造を呈していた.粘膜上皮は多列円柱上皮で杯細胞もみられた.筋層の一部は胃壁の筋層と連続していた.胃内腔との交通はなかった.今後超音波検査, CT検査で発見される腹腔内襲胞では本疾患も念頭におくべきである.
Reviving a Drug for Tuberculosis? (2017)

A compound called SMARt-420 renders ethionamide-resistant strains of Mycobacterium tuberculosis fully susceptible. This compound inhibits a hitherto unknown repressor of a molecule necessary for ethionamide activation.
A message-based fault diagnosis procedure (1986)

A new diagnostic message protocol that provides fault diagnosis capabilities for the communications in a distributed system environment is described. The protocol is designed to operate in conjunction with a standard end-to-end communication protocol and uses special messages to determine the system fault state. A diagnosis message is represented using a test dependency model that is derived from the system topology. These messages are used by an adaptive strategy designed to achieve specific objectives such as reduced testing cost. Using the test dependency model, a general purpose algorithm is developed for generating these strategies based on an information theory criterion. Specific properties of the protocol are discussed, and several examples of strategies for a distributed system topology are provided.
New Coordination Modes for Modified Schiff Base Ti(IV) Complexes and Their Control over Lactone Ring-Opening Polymerization Activity (2018)

A series of eight new bis(alkoxy)bis(phenoxy-imine)titanium(IV) catalysts, coordinated by Schiff base ligands derived from o-vanillin (2-hydroxy-3-methoxybenzaldehyde), show good activity and control for the ring-opening polymerization of ε-caprolactone and ω-pentadecalactone. The new complexes are easily prepared in two high-yield steps from commercial reagents. The new ligands can all adopt two different coordination modes, depending on the steric bulk on the imine: a six-membered N-O chelate and/or a five-membered O-O chelate. The complexes show three different structures, depending on the ligand coordination mode: type A (N-O:N-O), type B (N-O:O-O), and type C (O-O:O-O). In all cases, the structures were confirmed in solution using variable temperature NMR spectroscopy and in the solid state using X-ray crystallography. The complex structure influences the polymerization rate, with the catalytic activities decreasing in the order: type C > type B > type A for both monomers. Overall, the work demonstrates potential to use these new ligands to access particular coordination modes, which allows enhancement of catalytic activity.
Activating cellulose via its reversible reaction with CO2 in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene for the efficient synthesis of cellulose acetate (2015)

Reversible reaction of cellulose with CO<sub>2</sub> in DMSO/DBU results in a derivative dissolution of cellulose, which can be applied for the efficient acetylation of cellulose to afford cellulose acetates with degrees of substitution from 1.78–2.89.
A Hexokinase II Derived-Cell Penetrating Peptide Targets the Mitochondria and Triggers Apoptosis in Cancer Cells (2016)

Most cancers are characterized by a high rate of glycolysis and overexpression of mitochondrial-bound isoforms of hexokinase, an enzyme that phosphorylates glucose in an ATP-dependent manner and this commences the first committed step in glucose metabolism. Type II hexokinase (HK II) plays a paramount role in metabolic reprogramming in tumors and its association with the voltage dependent anion channel (VDAC), a major channel for transport of metabolites and ions across the mitochondrial membrane, inhibits apoptosis in cancer cells and is therefore an important therapeutic target. A peptide corresponding to the mitochondrial membrane-binding N-terminal domain of HK II (pHK II) can potentially compete with the endogenous protein for binding to mitochondria and trigger apoptosis. In vitro studies in HeLa cells showed that coupling of pHK II to a short penetration accelerating sequence (Pas: FFLIPKG) enhances the peptide's intracellular delivery and cytosolic release, followed by localization to the mitochondria. Cell viability assays revealed that pHK II-pas was considerably more effective in inhibiting cell growth compared to pHK II alone. Moreover, pHK II-pas displayed an enhanced ability to deplete cellular ATP levels and induce apoptosis. Mitochondrial function analysis showed that exposure to pHK II-pas peptide resulted in a significant decrease in glycolytic capacity and glycolytic reserve, as well as basal oxygen consumption rate (OCR), spare respiratory capacity, and ATP turnover. Importantly, these effects were correlated with HK II release from mitochondria. Thus, the mode of action of pHK II-pas involves release of the HK II protein from the mitochondrial membrane resulting in loss of mitochondrial membrane potential, decreased cellular ATP levels and finally apoptosis. Our results underline the potential of the pHK II-pas cell-penetrating peptide (CPP) as an innovative and effective anti-tumor therapeutic strategy.
Induced pluripotent stem cell–derived cardiomyocytes in studies of inherited arrhythmias (2013)

The discovery of the genetic basis of inherited arrhythmias has paved the way for an improved understanding of arrhythmogenesis in a wide spectrum of life-threatening conditions. In vitro expression of mutations and transgenic animal models have been instrumental in enhancing this understanding, but the applicability of results to the human heart remains unknown. The ability to differentiate induced pluripotent stem cells (iPSs) into cardiomyocytes enables the potential to generate patient-specific myocytes, which could be used to recapitulate the features of inherited arrhythmias in the context of the patient's genetic background. Few studies have been reported on iPS-derived myocytes obtained from patients with heritable arrhythmias, but they have demonstrated the applicability of this innovative approach to the study of inherited arrhythmias. Here we review the results achieved by iPS investigations in arrhythmogenic syndromes and discuss the existing challenges to be addressed before the use of iPS-derived myocytes can become a part of personalized management of inherited arrhythmias.
Investigation of the Effect of a Humid Air System on Diesel NOx and PM Emissions of a Small Diesel Engine (2011)

&lt;div class="section abstract"&gt;The effects of humid air on the performance of a naturally aspired three-cylinder diesel engine with low sulfur diesel fuel have been investigated. The additions of the humidity to intake air were performed with a variable steam generator using distilled water, where the relative humidity levels of the intake air were changed from the ambient conditions of 65% to 75% and 95% levels. The tests were performed at two approximate engine output brake horse powers (BHP) of 5.9, and 8.9. Results showed approximately 3.7% and 22.5% reduction in NO&lt;sub&gt;x&lt;/sub&gt; emissions when the relative humidity of the air was increased from 65% (the ambient relative humidity) to 75% and 95% respectively. The addition of the humidity results in increases in the CO, CO₂, and particulate matter (PM), by approximately 3.7, 3.55, 14.9 percents at 5.9 BHP and 22, 2.8, and 9.3 percents at 8.9 BHP. There was no change in the brake specific fuel consumption (BSFC) at 5.9 BHP and about 2.7 increase in the BSFC at 8.9 BHP. Results indicate that for both mobile and stationary diesel engines, humid air system is a viable option for attaining significant reductions in NO&lt;sub&gt;x&lt;/sub&gt; emissions.&lt;/div&gt;
The Effect of Rhizosphere Soil and Root Tissues Amendment on Microbial Mineralisation of Target 14 C-Hydrocarbons in Contaminated Soil (2016)

The effect of rhizosphere soil or root tissues amendments on the microbial mineralisation of hydrocarbons in soil slurry by the indigenous microbial communities has been investigated. In this study, rhizosphere soil and root tissues of reed canary grass (Phalaris arundinacea), channel grass (Vallisneria spiralis), blackberry (Rubus fructicosus) and goat willow (Salix caprea) were collected from the former Shell and Imperial Industries (ICI) Refinery site in Lancaster, UK. The rates and extents of 14C–hydrocarbons (naphthalene, phenanthrene, hexadecane or octacosane) mineralisation in artificially spiked soils were monitored in the absence and presence of 5% (wet weight) of rhizosphere soil or root tissues. Respirometric and microbial assays were monitored in fresh (0 d) and pre–incubated (28 d) artificially spiked soils following amendment with rhizosphere soil or root tissues. There were significant increases (P < 0.001) in the extents of 14C–naphthalene and 14C–phenanthrene mineralisation in fresh artificially spiked soils amended with rhizosphere soil and root tissues compared to those measured in unamended soils. However, amendment of fresh artificially spiked soils with rhizosphere soil and root tissues did not enhance the microbial mineralisation of 14C–hexadecane or 14C–octacosane by indigenous microbial communities. Apart from artificially spiked soil systems containing naphthalene (amended with reed canary grass and channel grass rhizosphere) and hexadecane amended with goat willow rhizosphere, microbial mineralisation of hydrocarbons was further enhanced following 28 d soil–organic contaminants pre–exposure and subsequent amendment with rhizosphere soil or root tissues. This study suggests that organic chemicals in roots and/or rhizosphere can enhance the microbial degradation of petroleum hydrocarbons in freshly contaminated soil by supporting higher numbers of hydrocarbon–degrading populations, promoting microbial activity and/or enhancing bioavailability of organic contaminants.
R-Functions in Boundary Value Problems in Mechanics (1995)

Described are the concepts and applications of the R-functions theory in continuum mechanics boundary value problems which model fields of different physical natures. With R-functions there appears the possibility of creating a constructive mathematical tool which incorporates the capabilities of classical continuous analysis and logic algebra. This allows one to overcome the main obstacle which hinders the use of variational methods when solving boundary value problems in domains of complex shape with complex boundary conditions, this obstacle being connected with the construction of so-called coordinate sequences. In contrast to widely used methods of the network type (finite difference, finite and boundary elements), in the R-functions method all the geometric information present in the boundary value problem statement is reduced to analytical form, which allows one to search for a solution in the form of formulae called solution structures containing some indefinite functional components. A method of constructing solution structures satisfying the required conditions of completeness has been developed. The structural formulae include the left-hand sides of the normalized equations of the boundaries of the domains or their regions being considered, thus allowing one to change the solution structure expeditiously when changing the geometric shape. Given in the work is a definition of the basic class of R-functions, solution with their help of the inverse problem of analytical geometry (construction of equations of specified configurations); generalization of the Taylor-Hermite formulae for functional spaces in which points are represented by lines and surfaces; and construction of solution structures of some types of boundary value problems. Shown are the solutions of a number of concrete problems in these application fields with the use of the RL language and POLYE system.
Fabbed to Sense: Integrated Design of Geometry and Sensing Algorithms for Interactive Objects (2016)

Task-specific tangible input devices, like video game controllers, improve user speed and accuracy in input tasks compared to the more general-purpose touchscreen or mouse and keyboard. However, while modifying a graphical user interface (GUI) to accept mouse and keyboard inputs for new and specific tasks is relatively easy and requires only software knowledge, tangible input devices are challenging to prototype and build.Rapid prototyping digital fabrication machines, such as vinyl cutters, laser cutters, and 3D printers, now permeate the design process for such devices. Using these tools, designers can realize a new tangible design faster than ever. In a typical design process, these machines are not used to create the interaction in these interactive product prototypes: they merely create the shell, case, or body, leaving the designer to, in an entirely separate process, assemble and program electronics for sensing a user's input. What are the most cost-effective, fast, and flexible ways of sensing rapid-prototyped input devices? In this dissertation, we investigate how 2D and 3D models for input devices can be automatically generated or modified in order to employ standard, off-the-shelf sensing techniques for adding interactivity to those objects: we call this ``fabbing to sense.''We describe the capabilities of modern rapid prototyping machines, linking these abilities to potential sensing mechanisms when possible. We plunge more deeply into three examples of sensing/fabrication links: we build analysis and design tools that help users design, fabricate, assemble, and \\emph{use} input devices sensed through these links. First, we discuss Midas, a tool for building capacitive sensing interfaces on non-screen surfaces, like the back of a phone. Second, we describe Lamello, a technique that generates lasercut and 3D printed tine structures and simulates their vibrational frequencies for training-free audio sensing. Finally, we present Sauron, a tool that automatically modifies the interior of 3D input models to allow sensing via a single embedded camera. We demonstrate each technique's flexibility to be used for many types of input devices through a series of example objects.
A Hardware-Oriented Method for Evaluating Complex Polynomials (2007)

A hardware-oriented method for evaluating complex polynomials by solving iteratively a system of linear equations is proposed. Its implementation uses a digit-serial iterations on simple and highly regular hardware. The operations involved are defined over the reals. We describe a complex-to-real transform, a complex polynomial evaluation algorithm, the convergence conditions, and a corresponding design and implementation. The latency and the area are estimated for the radix-2 case. The main features of the method are: the latency of about m cycles for an m-bit precision; the cycle time independent of the precision; a design consisting of identical modules; and a digit-serial connections between the modules. The number of modules, each roughly corresponding to serial-parallel multiplier without a carry-propagate adder, is 2(n + I) for evaluating an n-th degree complex polynomial. The method can also be used to compute all successive integer powers of the complex argument with the same latency and a similar implementation cost.
Pyrolytic laser assisted chemical vapor deposition of Al from dimethylethylamine-alane: Characterization and a new two-step writing process (1994)

We describe pyrolytic laser assisted chemical vapor deposition of Al from dimethylethylamine-alane with 514-nm radiation from an Ar ion laser. High purity Al lines with resistivity close to bulk Al are reported for a range of operating conditions. The relationship between operating parameters and materials properties of the deposited lines is delineated. Results from deposition on different substrates, Pt, Au, W, and Si, provide insight into thermal and nucleation effects in the laser writing process. Based on the observed nucleation behavior, we demonstrate a two-step fast writing process involving fast laser nucleation of lines, followed by selective chemical vapor deposition of Al on the nucleated pattern.
Development of specifications for the superpave simple performance tests (2009)

This study describes the development and establishment of a proposed Simple Performance Test (SPT) specification in order to contribute to the asphalt materials technology in the state of Michigan. The properties and characteristic of materials, performance testing of specimens, and field analyses are used in developing draft SPT specifications. These advanced and more effective specifications should significantly improve the qualities of designed and constructed hot mix asphalt (HMA) leading to improvement in pavement life in Michigan. The objectives of this study include the following: 1) using the SPT, conduct a laboratory study to measure the parameters including the dynamic modulus terms (E*/sinϕ and E*) and the flow number (Fn) for typical Michigan HMA mixtures, 2) correlate the results of the laboratory study to field performance as they relate to flexible pavement performance (rutting, fatigue, and low temperature cracking), and 3) make recommendations for the SPT criteria at specific traffic levels (e.g. E3, E10, E30), including recommendations for a draft test specification for use in Michigan. The specification criteria of dynamic modulus were developed based upon field rutting performance and contractor warranty criteria.