gebhart/patrepeval huggingface dataset:
Barriers to the implementation of point-of-care ultrasonography by physiotherapists in haemophilia treatment centres in Canada: a modified Delphi approach (2019)

Abstract Background In patients with haemophilia, evidence suggests that the physical examination alone is not sensitive enough to detect small amounts of blood within a joint. Attention has shifted to methods of improving the sensitivity of the physical examination through adding diagnostic modalities such as point-of-care ultrasonography (POC-US). Proficiency with the physical examination and understanding of the role of POC-US are important competencies for physiotherapists. Despite training, implementation of POC-US by physiotherapists in haemophilia treatment centres in Canada has been mixed. Aim Using a theory-based approach, the aim of the current study is to achieve expert consensus regarding the barriers to physiotherapy performed POC-US in haemophilia treatment centres in Canada using a modified Delphi approach. Materials and Methods Using the Knowledge-to-Action Framework and the Consolidated Framework for Implementation Research (CFIR), a modified Delphi approach was completed using the Modified BARRIERS Scale (MBS). Participants were blinded and consensus was reached over three rounds at the Canadian Hemophilia Society’s annual three-day conference. Results Twenty-two physiotherapists participated; 20 participants completed Round 1, and 21 completed Rounds 2 and 3. Four items of the MBS reached consensus: 1) The physiotherapist does not have time to read research related to POC-US; 2) The physiotherapist is isolated from knowledgeable colleagues with whom to discuss POC-US; 3) Administration will not allow POC-US implementation; 4) There is insufficient time on the job to implement new ideas. All four consensus items can be mapped to one domain of the CFIR: the inner setting. Conclusion The haemophilia treatment centre within a healthcare organisation appears to be an important target for addressing barriers to the implementation of physiotherapy performed POC-US.
Evaluatiekader benutting: aanpak en toepassingen (2010)

Het is van belang dat bij benuttingsmaatregelen inzichtelijk wordt wat de effecten ervan zijn op de doorstroming, veiligheid, leefbaarheid en het gedrag van weggebruikers. Daarnaast wordt inzicht in de (kosten)effectiviteit ook steeds belangrijker. Als de brede effecten van maatregelen goed bepaald worden, zijn investeringen in benutting beter te verantwoorden en kunnen in de operationele praktijk maatregelen effectiever worden ingezet. Deze bijdrage geeft een overzicht van de typen evaluaties die onderscheiden kunnen worden (van diepgaande effectanalyses tot expert judgement) en beschrijft deze. Verder wordt ingegaan op de stappen die voor het opzetten en uitvoeren van een (integrale) evaluatie nodig zijn. De mogelijke opzet van evaluaties wordt uitgewerkt aan de hand van een tweetal cases: de uitgebreide evaluatie van de Dynamax proeven en de quick scan evaluatie van de spitsstroken op de A12 tussen Gouda en Zoetermeer
Identification of stable genetic networks using convex programming (2008)

Gene regulatory networks capture interactions between genes and other cell substances, resulting in various models for the fundamental biological process of transcription and translation. The expression levels of the genes are typically measured in mRNA concentrations in micro-array experiments. In a so called genetic perturbation experiment, small perturbations are applied to equilibrium states and the resulting changes in expression activity are measured. This paper develops a novel algorithm that identifies a sparse stable genetic network that explains noisy genetic perturbation experiments obtained at equilibrium. Our identification algorithm can also incorporate a variety of possible prior knowledge of the network structure, which can be either qualitative, specifying positive, negative or no interactions between genes, or quantitative, specifying a range of interaction strength. Our method is based on a convex programming relaxation for handling the sparsity constraint, and therefore is applicable to the identification of genome-scale genetic networks.
The Multi-Media CD-Rom System for Educational Use (1987)

Recent market studies have shown CD-ROM systems to be gaining gradual acceptance in new applications in various fields.1)2) This acceptance is due to the CD-ROM system's great storage capacity, high data reliability cost effectiveness and ease of handling and delivery of media. One of the most suitable applications is in education / training in which electronic books and CAI materials are included.3)
The Effects of Solvents and Catalyst on the Decomposition of Peroxy-Benzoic Acid (1967)

過安息香酸(以下PBAと略す)の種々の溶媒中で窒素流通下の分解速度は反応初期においてはPBA濃度をこ関し1次であり,ぞの見掛けの分解速度定数(60℃)の順序は,ベンジルアルコール>シクロヘキサン>トルエン>ベンゼンで溶媒分子からの水素引き抜き難易の順序と一致する。分解の見掛けの活性化エネルギー(65～79℃)は,ベンゼン中29.1kcal/mol,トルエン中18.3kcal/molであった。空気流通下では酸素の抑制効果が現われ,PBAの分解速度(60～79℃)が窒素流通下の場合に比べて,ベンゼン1.75,トルエン0.97,シクロヘキサン33.4,ベンジルアルコール1.2倍おそくなることがわかった。またナフテン酸コバルト存在,窒素流通下のPBAの分解は各溶媒の場合でも著しく加速されるが,ベンゼン中では分解の進行とともに抑制効果がみられた。なおその分解初期のPBA分解の見掛けの活性化エネルギー(30～45℃)は15.1kcal/mol,トルエン中24.3kcal/molであり,無触媒の場合に比べて前者は活性化エネルギー,頻度因子の低下,後者は増加がみられた。空気流通下ではトルエン中の実験結果から著しき誘発分解が生起することを認めた。なおトルエン中のPBAの分解反応生成物について調べ,トルエン溶媒を例としてPBAの分解機構についてその分解速度および生成物組成より触媒,酸素効果その他の観点より考察し知見をえた。
Data from Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma (2023)

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; Activation of the phosphoinositide 3-kinase (PI3K)-AKT pathway has been implicated in melanoma based primarily on the prevalence of mutations in PTEN and NRAS. To improve our understanding of the regulation and clinical significance of the PI3K-AKT pathway in melanoma, we quantitatively measured the levels of phosphorylated AKT, its substrate GSK3α/β, and its negative regulator PTEN in clinical metastases. Results were compared with mutational status, clinical outcomes, and sites of metastasis.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; DNA and protein were isolated from dissected frozen melanoma metastases (&lt;i&gt;n&lt;/i&gt; = 96). Activating mutations of BRAF, NRAS, AKT, PIK3CA, and KIT were detected by mass spectroscopy genotyping. Phosphorylated AKT (Ser473 and Thr308), P-GSK3α/β, and PTEN protein expression were measured by reverse-phase protein array. A panel of human melanoma cells lines (&lt;i&gt;n&lt;/i&gt; = 58) was analyzed for comparison.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt; BRAF-mutant tumors had higher levels of P-AKT-Ser473 (&lt;i&gt;P&lt;/i&gt; = 0.01), P-AKT-Thr308 (&lt;i&gt;P&lt;/i&gt; = 0.002), and P-GSK3α/β (&lt;i&gt;P&lt;/i&gt; = 0.08) than NRAS-mutant tumors. Analysis of individual tumors showed that almost all tumors with elevated P-AKT had low PTEN levels; NRAS-mutant tumors had normal PTEN and lower P-AKT. Similar results were observed in melanoma cell lines. Stage III melanoma patients did not differ in overall survival based on activation status of the PI3K-AKT pathway. Brain metastases had significantly higher P-AKT and lower PTEN than lung or liver metastases.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusions:&lt;/b&gt; Quantitative interrogation of the PI3K-AKT pathway in melanoma reveals unexpected significant differences in AKT activation by NRAS mutation and PTEN loss, and hyperactivation of AKT in brain metastases. These findings have implications for the rational development of targeted therapy for this disease. (Clin Cancer Res 2009;15(24):7538–46)&lt;/p&gt;&lt;/div&gt;
Optimized Handling Stability Control Strategy for a Four In-Wheel Motor Independent-Drive Electric Vehicle (2019)

An optimized handling stability control strategy is put forward aiming at enhancing a four in-wheel independent-drive motors electric vehicle (4WIDEV) performance capable of handling and stability. The optimized control strategy is designed by a hierarchical control structure, which mainly includes vehicle motion controller and vehicle torque distribution controller. Lateral stability controller, in-vehicle motion controller, which yields the generalized force and generalized yaw moment required of the vehicle, is designed into two modes: an instability control mode and a continuous control mode, which mode is activated determining by stability judgment controller based on phase portraits of sideslip angle and yaw rate. When the vehicle state exceeds the stability envelope region, instability control mode based on envelope control is utilized by sliding mode control method, simultaneously controlling the two-vehicle states variables, whereas continuous control mode is performed with adaptive adjustment of the weight parameter according to pre-defined stability degree. The lateral stability controller with adaptive switching two modes exhibits excellent handling stability performance under normal driving conditions, especially under critical conditions, such as on low tire-road adhesion coefficient. The vehicle torque distribution controller assigns driving or regenerative braking torque to four wheels reasonably and efficiently to satisfy the generalized force and the generalize yaw moment acquired by the vehicle motion controller, which synchronously considers the motor output capability and tire friction ellipse constraints while maintains each wheel slip ratio within the stable range. The results in co-simulation experiments based on Carsim and MATLAB/Simulink verify the proposed control strategy, compared with other control strategies, and demonstrate the effective improvement 4WIDEV’s performance in terms of handling stability especially under critical conditions.
Low-power RT-level synthesis techniques: a tutorial (2005)

Power consumption and power-related issues have become a first-order concern for most designs and loom as fundamental barriers for many others. While the primary method used to date for reducing power has been supply voltage reduction, this technique begins to lose its effectiveness as voltages drop to below one volt and further reductions in the supply voltage begin to create more problems than are solved. Under these circumstances, the process of design and the automation tools required to support that process become the critical success factors. In the last decade, huge effort has been invested to come up with a wide range of design solutions that help solve the power dissipation problem for different types of electronic devices, components and systems. These techniques range from RTL power management and multiple voltage assignment, to power-aware logic synthesis and physical design, to memory and bus interface design. A number of representative low-power design techniques from this large set are explained. More precisely, basic techniques are described, that are applicable at RT-level and below, and have proved to hold good potential for power optimisation in practical design environments.
Fluid-pipeline-soil interaction at the seabed (2018)

In this thesis, two particular pipeline design issues on the fluid-structure-soil interaction spectrum are considered : (i) the on­ bottom stability and safe operation of subsea pipelines and cables, and (ii) predicting seabed trenching within the touchdown zone of risers connected to floating vessels. The first three chapters focus on pipeline-soil interaction with regard to the soil resistance available to prevent pipeline movement in various scenarios. The following two chapters explore the fluid mechanics around an oscillating two-dimensional cylinder representative of a riser near the seabed. In the final chapter, an experimental study on trenching beneath an oscillating cylinder is presented.
A new 111in‐bleomycin complex for combined radiotherapy and chemotherapy (1985)

Six days after tumor transplantation three daily intraperitoneal doses of 0.9% NaCl, bleomycin (BLM), or a new 111In-bleomycin complex (BLMC, 15 microCi/g body weight) were administered to glioma-bearing mice. After therapy, tumors in mice treated with 111In-BLMC were smaller than those treated with BLM. Sixteen days after the first injection tumor size for 111In-BLMC-treated mice was 560 (240-1,030) mm3, 1,980 (1,400-3,290) mm3 for BLM (P less than 0.025), and 4,830 (2,580-9,180) mm3 for NaCl (0.1 less than P less than 0.2). Thirteen days after tumor transplantation glioma-bearing mice received single intratumor injection of 0.9% NaCl, BLM, or 111In-BLMC (1.5 mCi, carried by 0.5 mg BLM/g tumor weight). The average tumor size for 111In-BLMC was smaller than that for BLM by a factor of 2.5-3.7. Host weights for these two groups were similar, and morphologic abnormalities were not found in kidney or liver.
FBK-HLT: A New Framework for Semantic Textual Similarity (2015)

This paper reports the description and performance of our system, FBK-HLT, participating in the SemEval 2015, Task #2 "Semantic Textual Similarity", English subtask. We submitted three runs with different hypothesis in combining typical features (lexical similarity, string similarity, word n-grams, etc) with syntactic structure features, resulting in different sets of features. The results evaluated on both STS 2014 and 2015 datasets prove our hypothesis of building a STS system taking into consideration of syntactic information. We outperform the best system on STS 2014 datasets and achieve a very competitive result to the best system on STS 2015 datasets.
Single-shot Characterization of sub-15fs Pulses with 40dB Dynamic Range (2011)

We present an extended version of the self-referenced spectral interferometry technique which allows for both spectral phase and intensity retrieval from a single-shot interferogram. Sub-15fs pulses are characterized by SRSI and feedback experiments demonstrate &gt;40dB dynamic range.
Cofacial assembly of partially oxidized metallomacrocycles as an approach to controlling lattice architecture in low-dimensional molecular solids. Synthesis and properties of cofacially joined silicon and germanium hemiporphyrazine polymers (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCofacial assembly of partially oxidized metallomacrocycles as an approach to controlling lattice architecture in low-dimensional molecular solids. Synthesis and properties of cofacially joined silicon and germanium hemiporphyrazine polymersCarl W. Dirk and Tobin J. MarksCite this: Inorg. Chem. 1984, 23, 25, 4325–4332Publication Date (Print):December 1, 1984Publication History Published online1 May 2002Published inissue 1 December 1984https://pubs.acs.org/doi/10.1021/ic00193a044https://doi.org/10.1021/ic00193a044research-articleACS PublicationsRequest reuse permissionsArticle Views147Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Data set for Transmit Antenna Subset Selection in Generalised Spatial Modulation Systems (2018)

Dataset supports: Mysore Rajashekar, R. et al (2018). Transmit Antenna Subset Selection in Generalised Spatial Modulation Systems. IEEE Transactions on Vehicular Technology.The existing literature on transmit antenna selection (TAS) aided spatial modulation (SM) systems extensively deals with the Euclidean distance (ED) based TAS owing to its high transmit diversity gain. In this paper, we consider the ED-TAS aided generalized spatial modulation (GSM) system that transmits multiple symbols in each channel use and characterise its attainable diversity gain. Secondly, we show that the minimum ED of the receive constellation does not grow beyond a certain point when the size of the signal set is sufficiently large, which facilitates low-complexity implementations of the ED-TAS aided SM system. Our numerical studies revealed that a signal-to-noise gain of about 8 dB is achievable by employing ED-TAS in the GSM system compared to its counterpart dispensing with ED-TAS.
Synthesis and acetolysis of the epimeric 7-tosyloxynorbornan-2-ones (1969)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and acetolysis of the epimeric 7-tosyloxynorbornan-2-onesPaul G. Gassman, James L. Marshall, and Joseph M. HornbackCite this: J. Am. Chem. Soc. 1969, 91, 21, 5811–5817Publication Date (Print):October 1, 1969Publication History Published online1 May 2002Published inissue 1 October 1969https://pubs.acs.org/doi/10.1021/ja01049a018https://doi.org/10.1021/ja01049a018research-articleACS PublicationsRequest reuse permissionsArticle Views38Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Using Mixed Reality and Machine Learning to Assist Caregivers in Nursing Home and Promote Well-being (2023)

The aging phenomenon in many of the developed countries all over the world, combined with the increase in life expectancy, has led to an increase in the number of elderly people resorting to nursing homes. In this context, the role of the caregiver is now a focus of increasing importance. The idea of ​​well-being combined with health and the provision of highly personalized quality care, requires a reengineering of the current concept/space of a nursing home. In this domain, Mixed Reality and Machine Learning have shown enormous potential to design new approaches to Information Systems to support caregiver activity. This redesign should be based on the empowerment of the caregiver and the facilitation of a more immersive support system for their activity and more suitable for a job that is in the field and not in the office, enabling them in real time with decision support information. This article, after an introduction to the reality of aging and the concept of the nursing home, makes a review of the state of the art of what has been the introduction of technology in nursing homes. As a contribution, this work proposes a model based on the combined use of Mixed Reality and Machine Learning, capable of redesigning the way caregivers are helped by empowering them.
Progressive retinal degeneration in a Dutch Shepherd. (2010)

Un chien militaire berger hollandais de l'armee francaise âge de deux ans a ete presente en consultation d'ophtalmologie a l'Ecole Nationale Veterinaire de Toulouse pour un deficit visuel se traduisant par une diminution de sa capacite operationnelle. A l'examen, l'animal montrait une mydriase anisocorique gauche associee a des lesions d'atrophie retinienne moderees sur l'œil droit, beaucoup plus severes sur l'œil gauche. Le chien presentait par ailleurs une degenerescence vitreenne debutante du cote gauche. L'examen echographique a confirme l'atteinte vitreenne tandis que l'electroretinographie a mis en evidence une atteinte fonctionnelle grave de la retine. L'examen histopathologique des globes oculaires, apres euthanasie de l'animal, a corrobore l'hypothese epidemio-clinique d'atrophie progressive de la neuroretine. Cette affection presumee hereditaire est, selon les auteurs, decrite pour la premiere fois chez le berger hollandais.
Tin-117m(4+)DTPA: pharmacokinetics and imaging characteristics in patients with metastatic bone pain. (1997)

Among the four potential bone pain palliation radionuclides, 117mSn(4+)DTPA demonstrates the highest bone uptake and retention. Some biokinetic and radionuclidic features of 117mSn(4+)DTPA are similar to other agents, but many features are different and unique and may make it an ideal bone pain palliation agent. Double-blind comparative studies are needed to determine its exact role in bone pain palliation.
Biolistic-mediated plasmid-free transformation for induction of hairy roots in tobacco plants (2017)

T-DNA of Ri-plasmid from Agrobacterium rhizogenes is able to trigger the hairy root syndrome in infected plants. This natural phenomenon is used to generate hairy root cultures predominantly only in dicotyledonous plants. We propose a new method of hairy roots induction without Agrobacterium-mediated transformation. The 5461 bp T-DNA region from A. rhizogenes A4 strain with all four rol genes was amplified using primers containing sequences for left and right T-DNA borders on their 3’-ends. This amplicon was used for direct transformation of tobacco leaf discs without A. rhizogenes and binary vectors. We showed the possibility of generation of hairy roots on tobacco leaf discs by biolistic transformation utilizing only rol genes amplicon.
Influence of the substrate temperature and deposition flux in the growth of a Bi thin film on the ten-fold decagonal Al-Ni-Co surface (2010)

We compare the growth of a Bi thin film on the ten-fold surface of the decagonal Al-Ni-Co quasicrystal at different substrate temperatures and fluxes using scanning tunneling microscopy (STM) and low energy electron diffraction (LEED). The growth at 29 K leads to the formation of a quasicrystalline monolayer, consistent with the results obtained at 300 K. Further deposition at low temperature produces pseudocubic islands with {100} surface orientation. The islands have two or four atomic layer heights. Both STM and LEED measurements reveal that there is a transition from the pseudocubic {100} film to the hexagonal {0001} surface orientation at coverage (θ) 4 < θ < 6 ML. The hexagonal domains are oriented along the high symmetry directions of the substrate. Growth at room temperature with different fluxes results in different island-height distributions. High flux predominantly produces islands of uniform four-layer high islands, whereas low flux yields islands of varying heights, yielding a rough film morphology. The two-layer high islands are found to be more stable at low temperature than at room temperature.
Wireless monitoring of an electric fleet hub (2011)

Lithium-ion battery packs are more prevalent in transportation applications. These batteries are typically characterized by their higher energy density and reduced need for maintenance. This paper will show how the intelligence needed for safe operation and long life of an electric vehicle's lithium-ion battery pack can be leveraged to provide a complete logistics solution that allows a fleet operator to accurately monitor true operations and maintenance costs.