gebhart/patrepeval huggingface dataset:
Hebbian synapses in cortical and hippocampal pathways (1998)

Use-dependent alterations in synaptic efficacy are believed to form the basis for such complex brain functions as learning and memory and significantly contribute to the development of neuronal networks. The algorithm of synapse modification proposed by Hebb as early as 1949 is the coincident activation of pre- and postsynaptic neurons. The present review considers the evolution of experimental protocols in which postsynaptic cell depolarization through the recording microelectrode was used to reveal the manifestation of Hebb-type plasticity in the synaptic inputs of the neocortex and hippocampus. Special attention is focused on the inhibitory control of the Hebb-type plasticity. Disinhibition within the local neuronal circuits is considered to be an important factor in Hebbian plasticity, contributing to such phenomena as priming, primed burst potentiation, hippocampal theta-rhythm and cortical arousal. The role of various transmitters (acetylcholine, norepinephrine, gamma-amino-butyric acid) in disinhibition is discussed with a special emphasis on the brain noradrenergic system. Possible mechanisms of Hebbian synapse modification and their modulation by memory enhancing substances are considered. It is suggested that along with their involvement in disinhibition processes these substances may control Hebb-type plasticity through intracellular second messenger systems.
Effects of Prostaglandins and the Autonomic Nervous System on the Vasodilatory Properties of Nitroglycerin in Conscious Dogs (1990)

This study was designed to assess the respective roles of prostaglandins and the autonomic nervous system in the responses to nitroglycerin (NTG) in conscious dogs. In vivo, NTG (1, 10, and 100 micrograms/kg i.v.) induced dose-dependent decreases in blood pressure and increases in heart rate and cardiac output. Coronary and carotid blood flows increased simultaneously, whereas responses in renal blood flow were biphasic, i.e., an initial decrease was followed by an increase above control at 10 and 100 micrograms/kg. NTG responses were not changed by indomethacin but were affected by chlorisondamine alone or in combination with indomethacin; tachycardia was abolished, and increases in cardiac output after 10 and 100 micrograms/kg were reduced by 26 and 32%, respectively, after ganglionic blockade and by 19 and 32%, respectively, after chlorisondamine plus indomethacin. In addition, increases in carotid blood flow in doses of 100 micrograms/kg were reduced by 88% after chlorisondamine and 83% after chlorisondamine plus indomethacin. Finally, in the presence of chlorisondamine plus indomethacin, NTG induced a more pronounced hypotension associated with a more pronounced renal vasodilation at the highest dose. Independent of indomethacin pretreatment, NTG in vitro induced a dose-dependent relaxation of the carotid, coronary, and renal arteries. Depending on the vascular bed, the reflex and local controls of circulation are affected differently by NTG.
[The pectoralis major flap: anatomic basis and indications in head and neck cancer surgery]. (2005)

Reconstruction by pectoralis major flap is scarce in our practice. The improvement of the results goes through the indications choice and the acquisition of more efficient technical stools.
End-to-end data integrity for file systems: a ZFS case study (2010)

We present a study of the effects of disk and memory corruption on file system data integrity. Our analysis focuses on Sun's ZFS, a modern commercial offering with numerous reliability mechanisms. Through careful and thorough fault injection, we show that ZFS is robust to a wide range of disk faults. We further demonstrate that ZFS is less resilient to memory corruption, which can lead to corrupt data being returned to applications or system crashes. Our analysis reveals the importance of considering both memory and disk in the construction of truly robust file and storage systems.
Supplementary Figure 1 from SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness (2023)

&lt;p&gt;FDM induces a stable increase in hERG current in a Sig1R-dependent manner but does not alter channel maturation&lt;/p&gt;
Access control method using electromyogram signal for consumer electronics system security (2021)

As the Internet of Things (IoT) technology develops, Consumer Electronics (CE) is equipped with network function, providing convenience to users. However, since they are connected to each other by network, hacking allows access to a variety of devices, and existing user recognition methods used to control the CE information has vulnerable security. In this paper, we proposed a CE access control method using Convolutional Neural Network-Long Short-Term Memory (CNN-LSTM) based Electromyogram (EMG) signal. EMG signal is preprocessed with a digital filter and then converted into a spectrogram, and the user is recognized using the designed CNN-LSTM. To verify the possibility of proposed CE access control method, the experiment was performed using Ninapro DB2. As a result of the experiment, twenty users showed 99.2% accuracy. In addition, experiment result showing 1.1% higher performance compared to the existing user recognition method using CNN. Therefore, possibility of CE access control using EMG signal of user was confirmed.
Flexible authentication of XML documents (2001)

XML is increasingly becoming the format of choice for information exchange, in critical areas such as government, finance, healthcare and law, where integrity is of the essence. As this trend grows, one can expect that documents (or collections thereof) may get quite large, and clients may wish to query for specific segments of these documents. In critical applications, clients must be assured that they are getting complete and correct answers to their queries. Existing methods for signing XML documents cannot be used to establish that an answer to a query is complete. A simple approach has a server processing queries and certifying answers by digitally signing them with an on-line private key; however, the server, and its on-line private key, would be vulnerable to external hacking and insider attacks. We propose a new approach to signing XML documents which allows untrusted servers to answer certain types of path queries and selection queries over XML documents without the need for trusted on-line signing keys. This approach enhances both the security and scalability of publishing information in XML format over the internet. In addition, it provides greater flexibility in authenticating parts of XML documents, in response to commercial or security policy considerations.
Endoscopic optical coherence tomography with a micromachined mirror (2003)

This paper presents experimental results of an endoscopic optical tomographic (EOCT) imaging system based on a micromachined mirror. Due to the use of the micromachined mirror, the endoscopic OCT system is highly suitable for non-invasive imaging diagnosis of a wide variety of inner organs. Ex-vivo imaging of rabbit bladder was performed. The microstructures of the bladder walls could be delineated with a traverse resolution of 20 /spl mu/m and an axial resolution of 10 /spl mu/m. The results have demonstrated the potential of EOCT for early diagnosis of bladder cancer and precise guiding of excisional biopsy.
Knowledge based genetic algorithm for dynamic route selection (2002)

Addresses the problem of selecting a route to a given destination on a road map under a dynamic environment. The proposed solution uses a genetic algorithm adopting viral infection. The method is to use the viruses as domain-specific knowledge. A part of an arterial road is regarded as a virus. We generate a population of viruses in addition to a population of routes. Crossover and infection determine the optimal combination of viruses. When traffic congestion changes during driving, an alternative route can be generated using the viruses and other routes in the population in the shortest time. Experiments using actual road maps show that the infection method is effective for this problem.
Account-sharing: a legitimate alternative to unlawful circumvention for the purposes of achieving content portability? (2012)

This article discusses the issue of content portability by providing copies to others. Since in many cases circumvention of digital rights management (DRM) is the only way forward in order to achieve content portability, the question arises whether it is similarly unlawful to share the account information, thus allowing the content to be accessed by a third party. For the purposes of this work content portability refers to the ability to play a work on several devices, to share files and to time-, space- or format-shift files. Therefore, this article concentrates on the private copying exception, which can be considered as the common denominator behind the aforementioned acts, in the context of which it is examined whether account-sharing can constitute an alternative legitimate option to unlawful circumvention of DRMs applied to works. To the extent this examination covers both USA and European developments in the area of anti-circumvention legislation interpretation it can be considered comparative. However, the main focus of this article is European law and its main purpose is to show that the sharing of account information in order to achieve content portability does not fall foul of the European anti-circumvention legislation and, thus, contribute to the wider dialogue for the development of a more balanced European digital copyright law.
Intraoral Pressure Measurement during Mastication of Kelp. (2001)

Masticatory pressure caused by chewing with molars was measured using a multiple-point sheet sensor. The sensor system is useful to directly indicate masticatory force and contact area with various subjects. Mastication of kelp snack, which is difficult to cut in several chewing strokes and thus seems to be a good food for masticatory training, was analyzed. Peak force, contact area at peak, peak pressure, duration, cycle time and impulse were highly varied among subjects, but were not influenced by the breaking force of the kelp. The experimental results show that humans did not change their masticatory pattern at least during the first several chews of the kelp samples which are difficult to cut with teeth. In the first chew, masticatory pressure is lower and duration and cycle time are longer than the following several chews. This suggests that subjects are afraid of an unknown sample texture. Individual peak force in mastication was independent of the contact area, but highly correlated with the peak pressure. Subjects with a high impulse value, corresponding to a large amount of work in mastication, had a high masticatory force, but did not show long duration.
Upper Gastrointestinal Bleeding From Leukemic Gastric Implants (2002)

Figure 1 A 23-year-old woman admitted with an acute myelogenous leukemic blast crisis, developed thrombocytopenia, melena, and anemia. An esophagogastroduodenoscopy was performed, revealing an erythematous, friable mucosa with multiple white plaques lining the entire gastric mucosa. A small feeding tube was in place
PocketSUMMIT: small-footprint continuous speech recognition (2007)

We present PocketSUMMIT, a small-footprint version of our SUMMIT continuous speech recognition system. With portable devices becoming smaller and more powerful, speech is increasingly becoming an important input modality on these devices. PocketSUMMIT is implemented as a variable-rate continuous density hidden Markov model with diphone context-dependent models. We explore various Gaussian parameter quantization schemes and find 8:1 compression or more is achievable with little reduction in accuracy. We also show how the quantized parameters can be used for rapid table lookup. We explore firstpass language model pruning in a finite-state transducer (FST) framework, as well as FST and n-gram weight quantization and bit packing, to further reduce memory usage. PocketSUMMIT is currently able to run a moderate vocabulary conversational speech recognition system in real time in a few MB on current PDAs and smart phones. Index Terms: speech recognition, small footprint, parameter quantization, finite-state transducer
Peer-produced privacy protection (2013)

Privacy risks have been addressed through technical solutions such as Privacy-Enhancing Technologies (PETs) as well as regulatory measures including Do Not Track. These approaches are inherently limited as they are grounded in the paradigm of a rational end user who can determine, articulate, and manage consistent privacy preferences. This assumes that self-serving efforts to enact privacy preferences lead to socially optimal outcomes with regard to information sharing. We argue that this assumption typically does not hold true. Consequently, solutions to specific risks are developed - even mandated - without effective reduction in the overall harm of privacy breaches. We present a systematic framework to examine these limitations of current technical and policy solutions. To address the shortcomings of existing privacy solutions, we argue for considering information sharing to be transactions within a community. Outcomes of privacy management can be improved at a lower overall cost if peers, as a community, are empowered by appropriate technical and policy mechanisms. Designing for a community requires encouraging dialogue, enabling transparency, and supporting enforcement of community norms. We describe how peer production of privacy is possible through PETs that are grounded in the notion of information as a common-pool resource subject to community governance.
Deep Learning for Survival Analysis: A Review (2023)

The influx of deep learning (DL) techniques into the field of survival analysis in recent years has led to substantial methodological progress; for instance, learning from unstructured or high-dimensional data such as images, text or omics data. In this work, we conduct a comprehensive systematic review of DL-based methods for time-to-event analysis, characterizing them according to both survival- and DL-related attributes. In summary, the reviewed methods often address only a small subset of tasks relevant to time-to-event data - e.g., single-risk right-censored data - and neglect to incorporate more complex settings. Our findings are summarized in an editable, open-source, interactive table: https://survival-org.github.io/DL4Survival. As this research area is advancing rapidly, we encourage community contribution in order to keep this database up to date.
Cadmium Telluride Gamma Camera (1979)

A small 4 cm X 4 cm prototype CdTe gamma camera has been constructed which demonstrates sensitivity and spacial resolution superior to the standard Anger camera. The camera is based on an array of linear solid state detectors contained within a laminar collimator which confines the field of view to one dimension. The array is rotated stepwise through 180° and data from each position recorded and computer processed. This technique leads to a major enhancement in sensitivity relative to the multihole collimator. Clinical images have been obtained and a larger CdTe camera is planned.
Chronic electronic cigarette exposure in mice induces features of COPD in a nicotine-dependent manner (2016)

Exposure to inhaled nicotine-containing e-cigarette fluids triggered effects normally associated with the development of COPD including cytokine expression, airway hyper-reactivity and lung tissue destruction. These effects were nicotine-dependent both in the mouse lung and in human airway cells, suggesting that inhaled nicotine contributes to airway and lung disease in addition to its addictive properties. Thus, these findings highlight the potential dangers of nicotine inhalation during e-cigarette use.
Genotropic theories of aging: an overview. (1980)

We have considered a rather wide-ranging number of genotropic theories of aging, defined as those which specify genomic alterations as the key to the understanding of the mechanisms of senescence. The fifteen ideas we have discussed are listed in Table 1, which divides them, in a rather arbitrary fashion, into two broad classes--those which emphasize modifications in gene structure and those which emphasize modifications in gene expression. It seems probable that no single one of these ideas will emerge as "the" underlying mechanism of aging, but that many of them will prove to have some credence. The aging process most certainly is under highly polygenic controls. In the case of human beings, I have made crude estimates [33] based upon a analysis of the phenotypes of known or suspected alleles at 2,336 genetic loci and the assumption of an upper limit for man of 100,000 informational loci, that anywhere from about 70-7000 genes could in fact be involved. This should not discourage us from pursuing a search for those loci which may be of profound importance to human aging as it ordinarily occurs in most human beings. In my opinion, however, the most pressing short-term need for biomedical gerontologists is to discover biochemical genetic reasons to explain why certain individuals seem especially prone to one or another of the age-related debilities, such as cancer, the various forms of arteriosclerosis, diabetes mellitus, osteoporosis, osteoarthritis, senile cataracts and senile dementia. Therefore, in my view, the future of progress in geriatric medicine is likely to be closely coupled to progress in medical genetics and genetic pathology.
Measurement of attack-Release Times in Compression Hearing Aids (1978)

A system for measurement of attack-release times in hearing aids with automatic-gain-control circuitry is described, with a view toward implementing that portion of the ANSI S3.22-1976 Standard in which parameters for these measurements are specified. Signal generation is accomplished by using a phased-array loudspeaker arrangement designed to produce transient-free pulsed acoustic sinusoids. Output waveforms are captured by a commercial transient recorder, and are displayed in either an oscilloscopic or graphic mode. A specific means of calculating attack and release times is recommended whereby variously shaped output waveforms are amenable to the basic protocol outlined in the ANSI Standard.
SiC/SiC Composites for Applications Above 2600 F (2004)

Using data from panels with 2D woven architectures,t his presentation describes progress in identifying advanced constituent materials and processes for achieving a high conductivity SiC/SiC composite system with long-term structural life under oxidizing conditions at 2600 degrees F. A key factor for this progress is the development of approaches at NASA GRC that allow the constituent SiC fiber and SiC matrix to display high thermal conductivity, high creep-rupture resistance and high microstructural stability at temperatures above 3000 degree F. Another important factor is the avoidance of free silicon in the SiC matrix, thereby providing the composites with the capability for extended service above the silicon melting point (2550 degrees F). The effects of utilizing various materials and processes for the SiC matrix are presented and discussed.
Multi-modal Agents for Business Intelligence (2021)

Given their installation on nearly a billion consumer devices around the world, consumers clearly enjoy using voice-driven assistants such as Alexa, Siri and Google Home, and find it compelling to interact with AI agents as quasi-human entities. Inevitably, people who are accustomed to using voice-driven assistants at home and in the car will expect to use such technologies in the workplace. What form will this take? Simple extrapolations from consumer space (e.g. running meetings or presentations) promise only modest value. I propose that AAMAS and the AI research community should pursue a bolder vision in which software agents act as quasi-human collaborators on core business intelligence tasks that entail analyzing data, diagnosing problems, and making decisions. Moreover, these business intelligence agents should communicate multi-modally, i.e. they must understand and employ speech complemented by non-verbal behaviors such as pointing, eye gaze, and facial expression. I outline requisite agent, MAS and AI technologies and pose several fundamental research challenges raised by this vision.
Biochemical and Physiological Regulation of Cardiac Myocyte Contraction by Cardiac-Specific Myosin Light Chain Kinase (2013)

Cardiac-specific myosin light chain kinase (cMLCK) is the kinase predominantly responsible for the maintenance of the basal level of phosphorylation of cardiac myosin light chain 2 (MLC2), which it phosphorylates at Ser-15. This phosphorylation repels the myosin heads from the thick myosin filament and moves them toward the thin actin filament. Unlike smooth muscle cells, MLC2 phosphorylation in striated muscle cells appears to be a positive modulator of Ca(2+) sensitivity that shifts the Ca(2+)-force relationship toward the left and increases the maximal force response and thus does not initiate muscle contraction. Recent studies have revealed an increasing number of details of the biochemical, physiological, and pathophysiological characteristics of cMLCK. The combination of recent technological advances and the discovery of a novel class of biologically active nonstandard peptides will hopefully translate into the development of drugs for the treatment of heart diseases.
Characterization of Metallic and Bimetallic Nanoparticles by Off-Axis Electron Holography (2014)

Journal Article Characterization of Metallic and Bimetallic Nanoparticles by Off-Axis Electron Holography Get access Jesús Cantú-Valle, Jesús Cantú-Valle Department of Physics and Astronomy, University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas 78249, United States Search for other works by this author on: Oxford Academic Google Scholar Francisco Ruiz-Zepeda, Francisco Ruiz-Zepeda Department of Physics and Astronomy, University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas 78249, United States Search for other works by this author on: Oxford Academic Google Scholar Ulises Santiago, Ulises Santiago Department of Physics and Astronomy, University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas 78249, United States Search for other works by this author on: Oxford Academic Google Scholar Fernando Mendoza-Santoyo, Fernando Mendoza-Santoyo Department of Physics and Astronomy, University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas 78249, United States Search for other works by this author on: Oxford Academic Google Scholar Miguel Jose-Yacaman, Miguel Jose-Yacaman Department of Physics and Astronomy, University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas 78249, United States Search for other works by this author on: Oxford Academic Google Scholar Arturo Ponce Arturo Ponce Department of Physics and Astronomy, University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas 78249, United States Search for other works by this author on: Oxford Academic Google Scholar Microscopy and Microanalysis, Volume 20, Issue S3, 1 August 2014, Pages 290–291, https://doi.org/10.1017/S1431927614003171 Published: 27 August 2014