gebhart/patrepeval huggingface dataset:
Shock of Vibration-based Technologies, Part I: Experimental Setup and Automated Identification (2015)

Feature extraction is essential in vibration-based Structural Health Monitoring (SHM). In this paper a special focus is on how features are extracted and conditioned. The first case is a numerical simulation study of a small test structure. The second case is an experimental case where two test subjects of a scaled wooden blade structure are investigated. In the experimental case the measurements are performed over a month in an environment with changing temperature and relative humidity. Two different damage types are made, with increasing severity of the damage. All methods dealing with vibration based SHM are using the changes in the dynamic behavior as an indicator for damage. In the test cases the modal parameters of the structure are used as features and are extracted using operational modal analysis (OMA) in a framework of modal tracking. This paper is part 1 of a series of 4 papers that present experimental SHM investigations with focus on value of detection and value of localization using statistical and physical methods for modal based SHM. doi: 10.12783/SHM2015/184
Immunization with Polyamine Transport Protein PotD Protects Mice against Systemic Infection with Streptococcus pneumoniae (2006)

The human pathogen Streptococcus pneumoniae contains genes for a putative polyamine ABC transporter which are organized in an operon and designated potABCD. Polyamine transport protein D (PotD) is an extracellular protein which binds polyamines and possibly other structurally related molecules. PotD has been shown to contribute to virulence in both a murine sepsis model and a pneumonia model with capsular type 3 pneumococci. The protective efficacy of recombinant PotD was evaluated by active immunization and intravenous challenge with capsular type 3 pneumococci in CBA/N mice. Immunized mice had 91.7% survival following lethal pneumococcal challenge, compared with 100% mortality in the control group. Immunized animals had high-titer anti-PotD antibodies following three immunizations with alum. Protection in a sepsis model was also seen after passive administration of rabbit antiserum raised against PotD (P < 0.004). These results suggest that antibodies to PotD confer protection against invasive pneumococcal disease and that this protein should be studied further as a potential vaccine candidate for protection against invasive pneumococcal infections.
Cholescintigraphy in patients with acute cholecystitis before and after percutaneous gallbladder drainage (1995)

The relief of increased gallbladder pressure and volume appears to be important for the re-establishment of gallbladder function.
Development of GIS-based spatial three-dimensional slope stability analysis system: 3DSlopeGIS (2004)

Based on a new IT technology-Geographic Information System (GIS), this paper presents a new slope analysis approach which can be used to identify the possible slope failure bodies from complicated topography. In a system, all slope-related spatial information (vector or raster dataset) are integrated; the study area is divided into Slope Unit which possesses approximate inclination; assuming the initial slip to be the lower part of an ellipsoid, the 3-D critical slip surface in the 3-D slope stability analysis is located by minimizing the 3-D safety factor using the Monte Carlo random simulation.The system 3DSlopeGIS has been validated based on the results of three cases study. Based on numerous times Monte Carlo simulation (30 millions per 1kre2 range), the possible slope failure bodies have been identified which is impossible by using transitional slope stability analyses.
NFV-VITAL: A framework for characterizing the performance of virtual network functions (2015)

Network Function Virtualization (NFV) brings a cloud service automation paradigm to demand-driven elastic flexing of infrastructure resources. Thus, it is essential to characterize the impact of hardware and virtualization options on the virtual network function (VNF) performance, and on the load on underlying infrastructure. In this paper, we present VNF characterization case studies with three sample open-source VNF platforms, the Clearwater IMS VNF and two intrusion detection system VNFs (Snort and Suricata). We demonstrate that VNF characterization is vital for optimizing VNF performance, as well as efficient utilization of infrastructure resources. We use the lessons learned from our case studies to design and implement a VNF characterization framework, NFV-VITAL, to characterize VNFs based on user preferences and available resources. We demonstrate how NFV-VITAL can automatically determine optimal configurations under different workloads with the three sample VNFs.
Image retrieval and perceptual similarity (2006)

Simple, low-level visual features are extensively used for content-based image retrieval. Our goal was to evaluate an image-indexing system based on some of the known properties of the early stages of human vision. We quantitatively measured the relationship between the similarity order induced by the indexes and perceived similarity. In contrast to previous evaluation approaches, we objectively measured similarity both for the few best-matching images and also for relatively distinct images. The results show that, to a large degree, the rank orders induced by the indexes predict the perceived similarity between images. The highest index concordance employing a single index was obtained using the chromaticity histogram. Combining different information sources substantially improved the correspondence with the observers. We conclude that image-indexing systems can provide useful measures for perceptual image similarity. The methods presented here can be used to evaluate and compare different image-retrieval systems.
vSocket: virtual socket interface for RDMA in public clouds (2019)

RDMA has been widely adopted as a promising solution for high performance networks, but is still unavailable for a large number of socket-based applications running in public clouds due to the following reasons. There is no available virtualization technique of RDMA that can meet the cloud's requirements. Moreover, it is cost prohibitive to rewrite the socket-based applications with the Verbs API. To address the above problems, we present vSocket, a software-based RDMA virtualization framework for socket-based applications in public clouds. vSocket takes into account the demands of clouds such as security rules and network isolation, so it can be deployed in the current public clouds. Furthermore, vSocket provides native socket API so that socket-based applications can use it without any modifications. Finally, to validate the performance gains, we implemented a prototype and compared it with current virtual network solutions against 1) basic network benchmarks and 2) the Redis, a typical I/O intensive application. Experimental results show that the latency of basic benchmarks can be reduced by 88% and the throughput of Redis is improved by 4 times.
Special Issue on Clusters and Computational Grids for Scientific Computing (2009)

International audience
A Totally Implanted Injection Port System for Blood Sampling and Chemotherapy Administration (1984)

We evaluated a totally implanted system consisting of a subcutaneous injection port connected to a silicone elastomer central venous catheter for vascular access, including blood drawing, in 35 patients with cancer. All patients lacked peripheral venous access sites and were undergoing aggressive chemotherapy programs. The cumulative duration of successful access exceeded 2,900 days (for individual patients: range, five to 203 days; median, 61 days). In no instance were infusions or injections unsuccessful. Blood-sampling attempts were successful 90% of the time. The system did not require flushing between uses, being filled with heparinized saline after each entry. There were no instances of irreversible catheter occlusion or shear and no system-related infections. Thus, this device appears to have advantages over other central venous catheters in terms of patient acceptance and lack of maintenance between uses.
Magnetically Recoverable CuFe2O4 Nanoparticles as Highly Active Catalysts for Csp3-Csp and Csp3-Csp3 Oxidative Cross-Dehydrogenative Coupling (2013)

This study probes the versatility of [metal] ferrite {[M]Fe<sub>2</sub>O<sub>4</sub>} nanoparticles as an effective catalyst platform for oxidative cross-dehydrogenative coupling (CDC) by comparing the reactivity of simple magnetite (Fe<sub>3</sub>O<sub>4</sub>) with that of the copper-substituted analogue, copper ferrite (CuFe<sub>2</sub>O<sub>4</sub>). In either case, the iron within the lattice enables magnetic recovery of the nanoparticles, simplifying the process of catalyst recycling. Both iron and copper effectively catalyze the CDC of two sp<sup>3</sup> carbons, while copper provides reactivity that iron cannot: activation of sp-hybridized carbons for coupling to sp<sup>3</sup> centers.
Effect of non-metallic inclusions and shrinkage cavities on the dynamic fracture toughness of a high-strength G42CrMo4 cast steel (2016)

The formation and clustering of non-metallic inclusions was investigated by applying a steel casting simulator. In a fully controlled atmosphere, the oxygen content of the steel melt was intentionally increased. At a specified level, the steel was deoxidized by pure aluminum. After the treatment, the melt was cooled down in the crucible. The effects of the inclusions and the cavities were determined by means of metallography, tensile tests, dynamic fracture toughness tests, and fractography. Metallographic results show that alumina particles have a strong tendency to aggregate at the walls of the crucible. Neglecting this aggregation, a relatively homogeneous distribution of alumina inclusions was observed. Furthermore, the solidified steel exhibited manganese sulphide inclusions and shrinkage cavities. The results of the tensile tests revealed a relatively low ductility. Fractographic examinations showed that both non-metallic inclusions and shrinkage cavities promoted ductile fracture. Results of dynamic fracture toughness tests revealed a relatively large scatter in the dynamic crack resistance. This was analogously attributed to the damaging effect of the non-metallic inclusions and the shrinkage cavities. Fractographic investigations showed that not only alumina inclusions but preferentially manganese sulphide inclusions affected the failure behavior of the investigated steel.
Removal of nucleus pulposus from the intervertebral disc – the use of chymopapain enhances mechanical removal with rongeurs: a laboratory study (2007)

Significantly more nucleus is removed using a bilateral than a unilateral approach; significantly more nucleus is removed if chymopapain is used in addition to rongeurs. A brush is useful in removing strands of nucleus loosened by chymopapain.
Methicillin-resistant Staphylococcus epidermidis in infection of hip arthroplasties (1994)

We investigated the incidence of cephalosporin-resistant bacteria in infected hip arthroplasties. Of 740 patients having hip replacement or related procedures performed over three years, 30 had positive bacteriological cultures from tissue removed at the time of surgery. In 18 of the 30 cultures Staphylococcus epidermidis was grown and 12 of these were methicillin-resistant. A prospective study of skin swabs taken from 100 consecutive patients at the time of admission for THR showed methicillin-resistant Staphylococcus epidermidis in 25. This cephalosporin-resistant organism was shown to be the commonest proven cause of infection, and its presence as a skin commensal raises important questions about current antibiotic prophylaxis for joint replacement.
A frequency‐based approach to locate common structure for 2D‐3D intensity‐based registration of setup images in prostate radiotherapy (2007)

In many radiotherapy clinics, geometric uncertainties in the delivery of 3D conformal radiation therapy and intensity modulated radiation therapy of the prostate are reduced by aligning the patient's bony anatomy in the planning 3D CT to corresponding bony anatomy in 2D portal images acquired before every treatment fraction. In this paper, we seek to determine if there is a frequency band within the portal images and the digitally reconstructed radiographs (DRRs) of the planning CT in which bony anatomy predominates over non-bony anatomy such that portal images and DRRs can be suitably filtered to achieve high registration accuracy in an automated 2D-3D single portal intensity-based registration framework. Two similarity measures, mutual information and the Pearson correlation coefficient were tested on carefully collected gold-standard data consisting of a kilovoltage cone-beam CT (CBCT) and megavoltage portal images in the anterior-posterior (AP) view of an anthropomorphic phantom acquired under clinical conditions at known poses, and on patient data. It was found that filtering the portal images and DRRs during the registration considerably improved registration performance. Without filtering, the registration did not always converge while with filtering it always converged to an accurate solution. For the pose-determination experiments conducted on the anthropomorphic phantom with the correlation coefficient, the mean (and standard deviation) of the absolute errors in recovering each of the six transformation parameters were Theta(x):0.18(0.19) degrees, Theta(y):0.04(0.04) degrees, Theta(z):0.04(0.02) degrees, t(x):0.14(0.15) mm, t(y):0.09(0.05) mm, and t(z):0.49(0.40) mm. The mutual information-based registration with filtered images also resulted in similarly small errors. For the patient data, visual inspection of the superimposed registered images showed that they were correctly aligned in all instances. The results presented in this paper suggest that robust and accurate registration can be achieved with intensity-based methods by focusing on rigid bony structures in the images while diminishing the influence of artifacts with similar frequencies as soft tissue.
An Image Analysis Resource for Cancer Research: PIIP—Pathology Image Informatics Platform for Visualization, Analysis, and Management (2017)

Pathology Image Informatics Platform (PIIP) is an NCI/NIH sponsored project intended for managing, annotating, sharing, and quantitatively analyzing digital pathology imaging data. It expands on an existing, freely available pathology image viewer, Sedeen. The goal of this project is to develop and embed some commonly used image analysis applications into the Sedeen viewer to create a freely available resource for the digital pathology and cancer research communities. Thus far, new plugins have been developed and incorporated into the platform for out of focus detection, region of interest transformation, and IHC slide analysis. Our biomarker quantification and nuclear segmentation algorithms, written in MATLAB, have also been integrated into the viewer. This article describes the viewing software and the mechanism to extend functionality by plugins, brief descriptions of which are provided as examples, to guide users who want to use this platform. PIIP project materials, including a video describing its usage and applications, and links for the Sedeen Viewer, plug-ins, and user manuals are freely available through the project web page: http://pathiip.org <i>Cancer Res; 77(21); e83-86. ©2017 AACR</i>.
Developmental Aspects of Contemporary Chemistry (1999)

The development of contemporary chemistry is surveyed, in an at- tempt at grasping philosophical consequences: first, chemical research has re- vealed a potentially endless diversity of matter, and an abysmal complexity of its organization at the molecular level. Second, we may conjecture from reflec- tions on some aspects of chemical reactivity that, owing to the limitations of human investigative means, reality is chemically unfathomable beyond a cer- tain limit. In some instances, this may impede our understanding of the func- tioning of natural systems in terms of molecular-structural organization. Third, the overall consistency of results obtained by applying different analyt- ical methods in order to establish molecular identity, along with the fact that we are able to interpret a great many different phenomena coherently in terms of molecular structure, indicates that matter - far from being something un- differentiated, easily moldable by the experiment, as anti-realistic views of sci- ence presuppose - really possesses a structure at the molecular level; a struc- ture that can be reorganized only according to a formal disposition inherent to matter itself.
Regio- and Stereoselective Synthesis of Multi-Alkylated Allylic Boronates through Three-Component Coupling Reactions between Allenes, Alkyl Halides, and a Diboron Reagent (2021)

Multisubstituted allylic boronates are attractive and valuable precursors for the rapid and stereoselective construction of densely substituted carbon skeletons. Herein, we report the first synthetic approach for differentially 2,3,3-trialkyl-substituted allylic boronates that contain a stereodefined tetrasubstituted alkene structure. Copper(I)-catalyzed regio- and stereoselective three-component coupling reactions between <i>gem</i>-dialkylallenes, alkyl halides, and a diboron reagent afforded sterically congested allylic boronates. The allylboration of aldehydes diastereoselectively furnished the corresponding homoallylic alcohols that bear a quaternary carbon. A computational study revealed that the selectivity-determining mechanism was correlated to the coordination of a boryl copper(I) species to the allene substrate as well as the borylcupration step.
SOLID PHASE EXTRACTION AND LC-MS/MS METHOD FOR QUANTIFICATION OF VENLAFAXINE AND ITS ACTIVE METABOLITE O-DESMETHYL VENLAFAXINE IN RAT PLASMA (2016)

A rapid, simple, sensitive LC-MS/MS method involving a least pretreatment process has been proposed for the quantitative assessment of venlafaxine (VEN) and O-desmethyl venlafaxine (ODV) using cetirizine as an internal standard. The method was validated over the range of 1.03 ng/mL to 453.50 ng/mL (venlafaxine) and 1.32 ng/mL to 585.21 ng/mL (O-desmethyl venlafaxine). The lowest limit of quantification for venlafaxine and O-desmethyl venlafaxine was found to be 1.03 ng/mL and 1.32 ng/mL, respectively. The solid phase extraction procedure provided reliable and reproducible recoveries of the drug as well as its active metabolite with no interference at their retention time. The recovery for all analyzed drugs was found to be in the range of 72.55% to 74.75%. The result indicates that the developed procedure could be considered suitable for carry out simultaneous preclinical pharmacokinetics studies for VEN and ODV.
Perceptual bit allocation for low rate coding of narrowband audio (2002)

In this work we consider adaptive bit allocation for perceptual coding of narrowband audio signals at low rates (down to 8 kbit/s). Two different strategies are used to shape the audible noise spectrum. In one approach, the quantization noise spectrum is shaped in parallel with the masking threshold curve. This way the noise is equally audible in different frequency bands. The other approach generates a flat noise spectrum above the masking threshold. The noise power is not equally distributed over the frequency range, hence it is audible to various extents at different frequencies.
Clinical Pathway Management of Tonsillectomy (2015)

The clinical pathway is being used increasingly as the standard hospital treatment policy for major disorders in Japan. Tonsillectomy accounts for most operations per year at many ear, nose, and throat facilities. Tonsillectomies accounted for 14.8% of 155 clinical pathway cases in the last 3 years at our hospital. The percentage of tonsil operations is second after ear surgery, at 18.4%, for the same number of nasal operations.Medical intern doctors usually perform tonsillectomies under the direction of senior doctors, and guidelines are needed to standardize hospital treatment and ensure safety against risks such as postoperative hemorrhage.It would also help to standardize team treatment to prevent preoperative infection in cooperation with health-care providers.
Eatty Acid Metabolism in Microorganisms Part I (1966)

The production of pimelic acid from azelaic acid by microorganisms was studied. About 100 strains of bacteria which were able to utilize azelaic acid as a sole carbon source were isolated from soil and other natural materials. Among these bacteria, several strains produced a large quantity of an organic acid (pimelic acid) from azelaic acid in their culture fluids during the cultivation. The acid was isolated from the culture fluid of strain A133 in crystalline form. The crystal was identified as pimelic acid by physico-chemical and biological methods. From the results of investigations on the morphological and physiological characters, the bacterial strain A133 was assumed to be Micrococcus sp.
Finite Element Analysis of Hillslope Variations in Surface Runoff (1990)

Watershed management decisions are aided through an accurate understanding of hydrologic processes. The finite element method applied to surface runoff with spatially variable hydraulic parameters provides the capability to accurately simulate surface runoff. Comparison of a finite element analysis to field measured values of flow depth and discharge on six hillslopes is reported.
Atomic Snapshots in O (n log n) Operations (1998)

The atomic snapshot object is an important primitive used for the design and verification of wait-free algorithms in shared-memory distributed systems. A snapshot object is a shared data structure partitioned into segments. Processors can either update an individual segment or instantaneously scan all segments of the object. This paper presents an implementation of an atomic snapshot object in which each high-level operation (scan or update) requires O(n log n) low-level operations on atomic read/write registers.