gebhart/patrepeval huggingface dataset:
de Haas–van Alphen oscillations in the quasi-two-dimensional organic conductorκ−(ET)2Cu(NCS)2: The magnetic breakdown approach (2002)

We present both experimental data and an analytic theory for the de Haas--van Alphen (dHvA) effect in the two-dimensional organic single-crystal conductor $\ensuremath{\kappa}\ensuremath{-}(\mathrm{ET}{)}_{2}\mathrm{Cu}(\mathrm{NCS}{)}_{2}.$ We show that the magnetization oscillation pattern and the fast Fourier transform (FFT) spectrum of our measurements are well described theoretically within the coherent magnetic breakdown (MB) model for a two-dimensional Fermi surface consisting of two open sheets and closed pockets connected by magnetic breakdown centers. The spectrum of Landau quantized energy levels changes substantially due to the MB. Landau bands develop whose bandwidth and relative distance between them oscillate in inverse magnetic field. These oscillations explain the observed fine structure of the magnetization pattern at fields above the MB field with the occurrence of ``forbidden'' frequencies in the FFT spectrum.
The Influence of the EU on Smart Sanctions Imposed on Russia and Their Effect on Russian Financial Institutions (2019)

Beginning in early 2014, the EU imposed and extended a range of smart sanctions on Russia concerning Russian involvement in destabilizing Ukraine and the violation of Ukraine’s territorial integrity. The EU imposed extra restrictive measures for Russian financial institutions to increase the cost of smart sanctions imposed on Russia. Thus, the paper analyses the impact of smart sanctions on Russian financial institutions. This was done through regression analyses with a dataset that covers 6 sanctioned and 31 non-sanctioned Russian banks. Sanctioned banks are identified by examining the EU’s and the US’s sectoral sanctions lists and those associated with individuals on theEU’s restrictive measures lists and the specially designated nationals lists of the US. The regression results suggest that after facing smart sanctions, sanctioned banks or banks associated with sanctioned individuals are less profitable compared with non-sanctioned banks. Furthermore, content analysis of annual reports of sanctioned banks reflects the vulnerability of the Russian banking sector towards smart sanctions; which curbed the financial position of Russian banks. Thus, smart sanctions on Russia appears to be “smart” in targeting the Russian financial institutions.
Melatonin in the duodenal lumen is a potent stimulant of mucosal bicarbonate secretion (2003)

Melatonin, originating from intestinal enterochromaffin cells, mediates vagal and sympathetic neural stimulation of the HCO secretion by the duodenal mucosa. This alkaline secretion is considered the first line of mucosal defense against hydrochloric acid discharged from the stomach. We have studied whether luminally applied melatonin stimulates the protective secretion and whether a melatonin pathway is involved in acid-induced stimulation of the secretion. Rats were anaesthetized (Inactin) and a 12-mm segment of proximal duodenum with an intact blood supply was cannulated in situ. Mucosal HCO secretion (pH-stat) and the mean arterial blood pressure were continuously recorded. Luminal melatonin at a concentration of 1.0 micro m increased (P < 0.05) the secretion from 7.20 +/- 1.35 to 13.20 +/- 1.51 micro Eq/cm/hr. The MT2 selective antagonist luzindole (600 nmol/kg, i.v.) had no effect on basal HCO secretion, but inhibited (P < 0.05) secretion stimulated by luminal melatonin. Hexamethonium (10 mg/kg i.v. followed by continuous i.v. infusion at a rate of 10 mg/kg/hr), abolishes neurally mediated rises in secretion and also inhibited (P < 0.05) the stimulation by luminal melatonin. Exposure of the lumen to acid containing perfusate (pH 2.0) for 5 min increased (P < 0.05) the HCO secretion from 5.85 +/- 0.82 to 12.35 +/- 1.51 micro Eq/cm/hr, and luzindole significantly inhibited (P < 0.05) this rise in secretion. The study thus demonstrates that luminal melatonin is a potent stimulant of duodenal HCO secretion and, furthermore, strongly suggests melatonin as an important mediator of acid-induced secretion.
Structural basis of HLA‐DO inhibition of HLA‐DM catalyzed peptide exchange on MHC class II (2011)

HLA‐DO (DO) is a non‐polymorphic, non‐classical MHC class II that is known to inhibit MHC class II peptide loading mediated by DM. The mechanism of inhibition by DO as well as the interactions between DO and DM remain unknown. Here, we present the 3D structure of the DM and DO complex determined by x‐ray crystallography at 3.2 Å resolution which is also the first resolved structure of DO. DO exhibits close structural similarity to the MHC class II molecule. The crystal complex shows DO residues mainly at the N‐terminal side of the α1 peptide‐binding groove interact with DM residues located at a concave surface. Some interactions are also observed involving DO residues from the IgG‐like domain. DM concave surface includes an acidic patch where residues in and surrounding this acidic patch and residues in the IgG‐like domain interact with DO. Interestingly, the interaction surface on DM to DO is spatially close to DM's interaction surface for DR that was suggested by molecular modeling and mutagenesis studies. The novel structure of the DM/DO complex presented here provides an insight on the possible mechanism of inhibition of DO on DM as well as the mechanism of how DM catalyzes peptide loading to peptide free DR.
Heparán sulfatos, amiloidosis y neurodegeneración (2017)

This study suggests that the fine structures of heparan sulphates, their localisation in cells and tissues, together with their local concentration, may regulate the amyloidosis processes. The advances made in the understanding of this area of glyconeurobiology will make it possible to improve the understanding of the cell and molecular mechanisms underlying the neurodegenerative process.
Preface: Cerebral Cortex Has Come of Age (1991)

In recent years, many new cortical areas have been identified in the macaque monkey. The number of identified connections between areas has increased even more dramatically. We report here on (1) a summary of the layout of cortical areas associated with vision and with other modalities, (2) a computerized database for storing and representing large amounts of information on connectivity patterns, and (3) the application of these data to the analysis of hierarchical organization of the cerebral cortex. Our analysis concentrates on the visual system, which includes 25 neocortical areas that are predominantly or exclusively visual in function, plus an additional 7 areas that we regard as visual-association areas on the basis of their extensive visual inputs. A total of 305 connections among these 32 visual and visual-association areas have been reported. This represents 31% of the possible number of pathways if each area were connected with all others. The actual degree of connectivity is likely to be closer to 40%. The great majority of pathways involve reciprocal connections between areas. There are also extensive connections with cortical areas outside the visual system proper, including the somatosensory cortex, as well as neocortical, transitional, and archicortical regions in the temporal and frontal lobes. In the somatosensory/motor system, there are 62 identified pathways linking 13 cortical areas, suggesting an overall connectivity of about 40%. Based on the laminar patterns of connections between areas, we propose a hierarchy of visual areas and of somatosensory/motor areas that is more comprehensive than those suggested in other recent studies. The current version of the visual hierarchy includes 10 levels of cortical processing. Altogether, it contains 14 levels if one includes the retina and lateral geniculate nucleus at the bottom as well as the entorhinal cortex and hippocampus at the top. Within this hierarchy, there are multiple, intertwined processing streams, which, at a low level, are related to the compartmental organization of areas V1 and V2 and, at a high level, are related to the distinction between processing centers in the temporal and parietal lobes. However, there are some pathways and relationships (about 10% of the total) whose descriptions do not fit cleanly into this hierarchical scheme for one reason or another. In most instances, though, it is unclear whether these represent genuine exceptions to a strict hierarchy rather than inaccuracies or uncertainities in the reported assignment.
Efficacy of Helicobacter pylori eradication therapies: a single centre observational study (2001)

Helicobacter pylori eradication rates can be maximised by using ranitidine bismuth citrate-clarithromycin-amoxicillin containing triple therapy, followed by bismuth and nitroimidazle containing second-line therapy, with third line combinations directed by sensitivity testing. Proton pump inhibitor-clarithromycin-metronidazole combinations should be avoided.
Actionneur tubulaire à réluctance variable pour assistance circulatoire médicale (2011)

National audience
Pressure-gain combustion (2015)

AccessScience is an authoritative and dynamic online resource that contains incisively written, high-quality educational material covering all major scientific disciplines. An acclaimed gateway to scientific knowledge, AccessScience is continually expanding the ways it can demonstrate and explain core, trustworthy scientific information that inspires and guides users to deeper knowledge.
Safety and Efficacy of Small Bowel Examination by Capsule Endoscopy for Patients before Liver Transplantation (2017)

<i>Background and Aims</i>. Gastrointestinal surveillance is a requirement prior to liver transplantation (LT), but small intestine examination is not generally undertaken. The aim of the present study was to evaluate the safety and efficacy of capsule endoscopy (CE) for patients with end-stage liver disease. <i>Methods</i>. 31 patients who needed LT were enrolled, and 139 patients who underwent CE over the same period of time acted as controls. <i>Results</i>. Frequency of successful achievement of evaluation of the full length of the small bowel, the mean gastric transit time, and the mean small bowel transit time were not significantly different between the two groups. Abnormalities in the small bowel were found in 26 patients. Comparative analysis revealed that history of EV rupture, history of EV treatment, red color sign of EV, and presence of PHG or HCC were significantly associated with patients with >2 two such findings (high score group). <i>Conclusions</i>. Small bowel examination by CE in patients before liver transplantation could be performed safely and is justified by the high rate of abnormal lesions detected particularly in patients with history of EV therapy or bleeding, red color sign, and presence of PHG or HCC. This study was registered in the UMIN Clinical Trial Registry (UMIN 000008672).
Research on Dynamic Characteristics of Gauge Change Bogies (2018)

Gauge change bogies have been extensively developed to solve the problem of different railway track gauges (narrow, standard, broad) among countries. This paper summarizes the different kinds of the gauge change bogies over the world. And the gauge change bogies are classified into two types, which are the bogie with independently rotating wheels and the one with traditional wheelsets, by referring to the patterns of the relatively rotation of the vehicle wheels. In this study, according to the performance characteristics of these two kinds of gauge change bogies, the dynamic characteristics between them are compared and analyzed by using SIMPACK simulation software based on vehicle dynamics theory.
Dopamine/Serotonin Receptor Ligands. 16. Expanding Dibenz[d,g]azecines to 11- and 12-Membered Homologues. Interaction with Dopamine D1−D5 Receptors (2007)

Oxygenated 7-methyl-5,6,7,8,9,14-hexahydrodibenz[d,g]azecines are potent dopamine receptor antagonists, preferentially at D1/D5. We synthesized the hydroxylated, methoxylated, and chlorinated 11-membered and 12-membered homologues of these 10-membered heterocycles. Their affinities for the human cloned D1-D5 receptors (radioligand binding) and functionalities (calcium assay) were measured. Enlarging the dibenzazecines to the corresponding dibenzazacycloundecenes and dibenzazacyclododecenes generally maintains the high antagonistic affinity for D1/D5 but also leads to a compound with a clozapine-like binding profile due to additional affinity for D4.
A Play to Be Performed: Excerpts from the Gertrude Stein Symposium at New York University (2002)

Research Article| May 01 2002 A Play to Be Performed: Excerpts from the Gertrude Stein Symposium at New York University Bevya Rosten; Bevya Rosten Search for other works by this author on: This Site Google Anne-Marie Levine; Anne-Marie Levine Search for other works by this author on: This Site Google Catharine Stimpson; Catharine Stimpson Search for other works by this author on: This Site Google Richard Howard; Richard Howard Search for other works by this author on: This Site Google Wendy Steiner; Wendy Steiner Search for other works by this author on: This Site Google Maria Irene Fornes; Maria Irene Fornes Search for other works by this author on: This Site Google Mac Wellman; Mac Wellman Search for other works by this author on: This Site Google Al Carmines; Al Carmines Search for other works by this author on: This Site Google Richard Foreman; Richard Foreman Search for other works by this author on: This Site Google Charles Bernstein; Charles Bernstein Search for other works by this author on: This Site Google ... Show more Jane Bowers Jane Bowers Search for other works by this author on: This Site Google Theater (2002) 32 (2): 3–25. https://doi.org/10.1215/01610775-32-2-3 Cite Icon Cite Share Icon Share Twitter Permissions Search Site Citation Bevya Rosten, Anne-Marie Levine, Catharine Stimpson, Richard Howard, Wendy Steiner, Maria Irene Fornes, Mac Wellman, Al Carmines, Richard Foreman, Charles Bernstein, Jane Bowers; A Play to Be Performed: Excerpts from the Gertrude Stein Symposium at New York University. Theater 1 May 2002; 32 (2): 3–25. doi: https://doi.org/10.1215/01610775-32-2-3 Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search Books & JournalsAll JournalsTheater Search Advanced Search The text of this article is only available as a PDF. © 2002 by Yale School of Drama/Yale Repertory Theatre2002 Article PDF first page preview Close Modal Issue Section: Articles You do not currently have access to this content.
Post-polymerisation modification of poly(3-hydroxybutyrate) (PHB) using thiol–ene and phosphine addition (2023)

Post modification of biodegradable polyesters as biodegradable dispersants.
Autoradiographic mapping of dopamine‐D2/D3 receptor stimulated [35S]GTPγS binding in the human brain (2005)

Agonist stimulated [35S]guanosine 5'-gamma-thiotriphosphate ([35S]GTPgammaS) binding autoradiography was established for the examination of dopamine-D2/D2 receptors in human brain sections. The distribution of G proteins activated by dopamine-D2/D3 receptors was studied in whole hemisphere cryosections. Dopamine stimulated [35S]GTPgammaS binding in brain regions with high densities of dopamine D2-like receptors, i.e. putamen (23 +/- 2%, mean +/- SEM,% stimulation over basal binding), caudate (20 +/- 0%) and substantia nigra (22 +/- 2%), but also in regions with lower receptor densities such as amygdala (17 +/- 8%), hippocampus (16 +/- 6%), anterior cingulate (13 +/- 3%), and thalamus (12 +/- 2%). Dopamine stimulated [35S]GTPgammaS binding to significantly higher levels in the dorsal than in the ventral part of the striatum. Dopamine caused low or very low stimulation in all cortical areas. Raclopride, a selective D2/D3 receptor antagonist, potently inhibited dopamine stimulated [35S]GTPgammaS binding, whereas R(+)-7-chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride (SCH23390), a selective D1 antagonist, did not block the [35S]GTPgammaS binding response stimulated by dopamine. Hence, the stimulatory effect of dopamine was primarily mediated by D2/D3 receptors. Quinpirole stimulated [35S]GTPgammaS binding in the same regions as dopamine. The maximal level of stimulation induced by dopamine and quinpirole was not significantly different. The present study demonstrates that agonist stimulated [35S]GTPgammaS binding autoradiography could be a suitable technique for the examination of dopamine-D2/D3 receptors in the human brain. This functional assay could provide useful new information about dopamine receptor/G protein coupling in the postmortem human brain, and reveal possible disease related alterations of the interaction between D2/D3 receptors and G proteins.
Comparison of the Gas-phase Basicities and Relative Methylation Nucleophilicities of Carbonyl-containing Compounds (1996)

The gas-phase basicities and relative methylation nucleophilicities of a series of simple cyclic carbonyl-containing compounds were evaluated in order to understand the low reactivities of some barbiturates and anti-convulsants in the gas phase. The gas-phase basicities were determined by the bracketing method, and the relative methylation nucleophilicities were characterized by monitoring ion–molecule reactions with CH3OCH2+ ions from dimethyl ether. Heats of formation were calculated for the protonated and methylated structures in order to estimate the favored sites of protonation and methylation. As shown in this paper, the positions of the carbonyl groups have a striking effect on the relative gas-phase basicities and methylation rates within a related series of compounds. For those compounds with two carbonyl groups in 1,2 positions, the methylation efficiency is enhanced by a factor of 100 over those compounds with two carbonyl groups in the 1,3 or 1,4 positions. This large difference is attributed to the variation in molecular dipole moments of the three cyclohexanediones and the relative positions of the two carbonyl groups. Cyclohexane-1,2-dione has the greatest dipole moment, leading to the highest interaction energy with the CH3OCH2+ reactant, and has the capability for cooperative interaction during the attack on CH3OCH2+ and subsequent rapid methyl cation transfer between the two carbonyl groups, thus enhancing the reaction rate and product stability. The order of gas-phase basicities is also strongly influenced by the number and positions of the carbonyl groups and the presence of a nitrogen atom in the ring. For example, glutarimide, which has two carbonyl groups surrounding a nitrogen atom in the ring, has a gas-phase basicity that is about 10 kcal mol-1 less than that of cyclohexane-1,3-dione. This result is attributed to the restriction of partial hydrogen-bond formation between the two carbonyl groups in glutarimide because of increased planarity of the ring due to the nitrogen atom.
High-Performance and Energy-Effcient Memory Scheduler Design for Heterogeneous Systems (2018)

When multiple processor cores (CPUs) and a GPU integrated together on the same chip share the off-chip DRAM, requests from the GPU can heavily interfere with requests from the CPUs, leading to low system performance and starvation of cores. Unfortunately, state-of-the-art memory scheduling algorithms are ineffective at solving this problem due to the very large amount of GPU memory traffic, unless a very large and costly request buffer is employed to provide these algorithms with enough visibility across the global request stream. Previously-proposed memory controller (MC) designs use a single monolithic structure to perform three main tasks. First, the MC attempts to schedule together requests to the same DRAM row to increase row buffer hit rates. Second, the MC arbitrates among the requesters (CPUs and GPU) to optimize for overall system throughput, average response time, fairness and quality of service. Third, the MC manages the low-level DRAM command scheduling to complete requests while ensuring compliance with all DRAM timing and power constraints. This paper proposes a fundamentally new approach, called the Staged Memory Scheduler (SMS), which decouples the three primary MC tasks into three significantly simpler structures that together improve system performance and fairness. Our evaluation shows that SMS provides 41.2% performance improvement and fairness improvement compared to the best previous state-of-the-art technique, while enabling a design that is significantly less complex and more power-efficient to implement.
Conversion of the maltogenic α-amylase Novamyl into a CGTase (2000)

Novamyl is a thermostable five-domain maltogenic alpha-amylase that shows sequence and structural homology with the cyclodextrin glycosyltransferases (CGTases). Comparing X-ray crystal structures of Novamyl and CGTases, two major differences in the active site cleft were observed: Novamyl contains a loop insertion consisting of five residues (residues 191-195) and the location of an aromatic residue known to be essential to obtain an efficient cyclization reaction. To convert Novamyl into a cyclodextrin (CD)-producing enzyme, the loop was deleted and two substitutions, F188L and T189Y, were introduced. Unlike the parent Novamyl, the obtained variant is able to produce beta-CD and showed an overall conversion of starch to CD of 9%, compared with CGTases which are able to convert up to 40%. The lower conversion compared with the CGTase is probably due to additional differences in the active site cleft and in the starch-binding E domain. A variant with only the five-residue loop deleted was not able to form beta-CD.
3D measurement of flexible objects by robust motion stereo (2007)

We propose a novel three-dimensional measurement approach of flexible cables for factory automation applications, such as cable handling, connecter insertion without conflicts with cables by using robotic arms. The approach is based on motion stereo with a vision sensor. To solve stereo correspondence problem efficiently, feature point extraction from cables and a robust texture matching based feature tracking is applied. Additionally, by using stability analysis of the feature point tracking, defective feature points can be rejected and stable 3-D shape reconstruction is achieved. In our experiments, shapes of arch-like cables have been measured to an accuracy of 5 mm. It is enough to find connecters without conflicts with the cables.
Role of Saliva in Blood-Feeding by Arthropods (1987)

Although the insect circulatory system is involved in a multitude of vital physiological processes, it has gone grossly understudied. This review highlights this critical physiological system by detailing the structure and function of the circulatory ...Read More