gebhart/patrepeval huggingface dataset:
Conformal Factor Persistence for Fast Hierarchical Cone Extraction (2017)

This paper presents a new algorithm for the fast extraction of hierarchies of cone singularities for conformal surface parameterization. Cone singularities have been shown to greatly improve the distortion of such parameterizations since they locally absorb the area distortion. Therefore, existing automatic approaches aim at inserting cones where large area distortion can be predicted. However, such approaches are iterative, which results in slow computations, even often slower than the actual subsequent parameterization procedure. This becomes even more problematic as often the user does not know in advance the right number of needed cones and thus needs to explore cone hierarchies to obtain a satisfying result. Our algorithm relies on the key observation that the local extrema of the conformal factor already provide a good approximation of the cone singularities extracted with previous techniques, while needing only one linear solving where previous approaches needed one solving per hierarchy level. We apply concepts from persistent homology to organize very efficiently such local extrema into a global hierarchy. Experiments demonstrate the approximation quality of our approach quantitatively and report time-performance improvements of one order of magnitude, which makes our technique well suited for interactive contexts.
Anisotropic material properties of fused deposition modeling ABS (2002)

Rapid Prototyping (RP) technologies provide the ability to fabricate initial prototypes from various model materials. Stratasys Fused Deposition Modeling (FDM) is a typical RP process that can fabricate prototypes out of ABS plastic. To predict the mechanical behavior of FDM parts, it is critical to understand the material properties of the raw FDM process material, and the effect that FDM build parameters have on anisotropic material properties. This paper characterizes the properties of ABS parts fabricated by the FDM 1650. Using a Design of Experiment (DOE) approach, the process parameters of FDM, such as raster orientation, air gap, bead width, color, and model temperature were examined. Tensile strengths and compressive strengths of directionally fabricated specimens were measured and compared with injection molded FDM ABS P400 material. For the FDM parts made with a 0.003 inch overlap between roads, the typical tensile strength ranged between 65 and 72 percent of the strength of injection molded ABS P400. The compressive strength ranged from 80 to 90 percent of the injection molded FDM ABS. Several build rules for designing FDM parts were formulated based on experimental results.
Damage to porous SiCOH low- k dielectrics by O, N and F atoms at lowered temperatures (2020)

Abstract Information on the degradation of porous organosilicate glasses (OSGs) by active radicals and atoms is of high importance for their integration as low- k dielectrics in the next generation of ultra large scale integration (ULSI) production. The films’ degradation is caused by depletion of coverage of the pore surface methyl. OSG samples with differing porosities and pore sizes were treated by O, N, and F atoms at lowered temperatures (down to −45 °С) downstream of O 2 , N 2 , and SF 6 inductively coupled plasma discharges, respectively. It has been shown that lowering the temperature reduces film degradation. In the case of O atoms, this reduction is insignificant, while the effect is much more noticeable for F atoms. In addition, an accumulation of F atoms forms a fluorocarbon layer during F atom treatment. The accumulated fluorine can interact with surface Si atoms, giving rise to film etching. The film degradation under O and F atoms increases with pore size and porosity, due to deeper atom penetration. In the case of N atoms, even a small temperature reduction essentially decreases OSG degradation, while –CH 3 modification is less clear in the cases of O and F atoms. Density functional theory and ab initio molecular dynamics simulations of reaction mechanisms show that atom reactions with surface Si–CH 3 groups are the initial stages of OSG degradation. Subsequent mechanisms include branched reaction pathways with the formation, modification, and destruction of different surface groups. In the cases of O and F atoms, these reactions lead to the formation of H x CО and CF x bonds. For the direct reaction of N( 4 S) atoms with –СН 3 groups, significant activation energy is required. Under downstream plasma conditions, –СН 3 groups are destroyed in reactions with metastable particles, and first of all, with metastable atoms N( 2 D), N( 2 P) and molecules , which are also produced inside the pores in the surface recombination of nitrogen atoms.
Electrical Conduction in Glass Ceramics Containing Metal Nanodispersoids (2003)

Silver particles of diameters ranging from 3.4 to 25.8 nm have been grown within a glass ceramic by controlling the morphology of the crystalline phase. The fractal dimension of the crystal phase has a marked effect on the particle diameter. The DC electrical resistivity of the glass–ceramic metal nanocomposites has been measured over the temperature range from 100 to 300 K. A variable-range hopping conduction between localized states generated by silver nanoparticles within the glass determines the resistivity behavior in the temperature range from 235 to 333 K. Electrical resistivity in the range from 110 to 235 K arises due to the contribution of both large and small metallic particles (∼3 nm) in a percolative configuration. The smaller particles show semiconducting behavior due to a quantum size effect. In the specimen containing 25.8-nm-median-diameter nanoparticles of silver, the resistivity arises through an electron tunnelling mechanism.
Suspension of sand due to wave groups (1991)

Field observations of the suspension of sand near the seabed under shoaled waves in the nearshore region are presented and discussed with regard to the influence of wave groups. Sand is found to be suspended at both the incident wave frequency and at lower frequencies corresponding to wave groups. These limited observations indicate the likelihood that wave groups result in higher concentrations of suspended sand than randomly distributed waves of similar heights.
Polygenic Contribution in Individuals With Early-Onset Coronary Artery Disease (2018)

These results suggest a significant polygenic contribution in individuals presenting with EOCAD, which could be more prevalent than familial hypercholesterolemia. Determination of the polygenic risk component could be included in the diagnostic workup of patients with EOCAD.
Structure and Properties of a Human Non-pancreatic Phospholipase A2 (1989)

We have purified a human non-pancreatic phospholipase A2 that is present in platelets and is enriched in rheumatoid synovial fluid. The enzyme is calcium-dependent, has a pH optimum of 8-10, and shows a striking preference for substrate presented in the form of Escherichia coli membranes. In the E. coli phospholipase A2 assay the phospholipase exhibits an apparent specific activity of 300 mumol/mg/min. Using oligonucleotide probes based on amino-terminal sequence data, we cloned the corresponding human gene from a genomic DNA library and expressed the gene in animal cells. The protein was secreted from the cells in an active form. The deduced amino acid sequence of the human protein consists of 124 amino acids, contains structural features common to all known phospholipase A2s, and has a half-cystine pattern that is characteristic of the snake venom group II enzymes.
A lab-scale Rich-Quench-Lean (RQL) combustor for stability and soot investigations (2018)

This study sought to characterize the soot emissions from a model rich-quench-lean (RQL) combustor, with special emphasis on the effect of dilution jet location and flow rate. The burner consisted of axial injection of ethylene, primary and secondary swirling air streams, and four dilution (quenching) radial air jets located at a variable distance downstream. A scanning mobility particle sizer (SMPS) was used in conjunction with a centrifugal particle mass analyzer (CPMA). The SMPS provided information on particle size distribution (PSD) and particle number (PN) and the CPMA provided mass characteristics of the emitted particles. For a constant global fuel-to-air ratio, increasing the proportion of air injected through the quenching jets resulted in fewer particles emitted and smaller mean particle sizes. The same trends were established in moving the injection point closer to the inlet of the combustion chamber. Introducing air into the secondary swirling flow had only a minor effect compared to the major changes observed with the use of quenching air. Depending on the condition, the mean particle size was in the range 20-50 nm and an optimum quenching jet location and flow rate was found, where the total mass and the mean particle size were a minimum. The results are useful for validating turbulent combustion models and highlight the large sensitivity of combustor-out soot emissions to the air flow split and dilution jet location.
Subspace Averaging for Source Enumeration in Large Arrays (2018)

Subspace averaging is proposed and examined as a method of enumerating sources in large linear arrays, under conditions of low sample support. The key idea is to exploit shift invariance as a way of extracting many subspaces, which may then be approximated by a single extrinsic average. An automatic order determination rule for this extrinsic average is then the rule for determining the number of sources. Experimental results are presented for cases where the number of array snapshots is roughly half the number of array elements, and sources are well separated with respect to the Rayleigh limit.
Membrane currents in human intercostal muscle at varied extracellular potassium (1984)

Hyperpolarizing and depolarizing square steps were imposed on the membrane potential of excised human intercostal muscle fibers by means of a 3-microelectrode voltage clamp. The steady-state amplitudes of the membrane currents inducing such steps were investigated as a function of the membrane potential, while the muscle was bathed in solutions varying in potassium content (Ke = 1, 3.5, 7, 20, and 60 mM). At all potassium concentrations, the membrane acted as a rectifier, both in the inward- and outward-going directions. Inward currents were much reduced when Ke was lowered from 3.5 to 1 mM, and were increased when Ke was raised beyond 3.5 mM. The delayed outward current was reduced when Ke was increased from 3.5 mM to 7 mM and higher potassium concentration. The results were qualitatively similar to those reported for rat skeletal muscle.
TrAp: a tree approach for fingerprinting subclonal tumor composition (2013)

Revealing the clonal composition of a single tumor is essential for identifying cell subpopulations with metastatic potential in primary tumors or with resistance to therapies in metastatic tumors. Sequencing technologies provide only an overview of the aggregate of numerous cells. Computational approaches to de-mix a collective signal composed of the aberrations of a mixed cell population of a tumor sample into its individual components are not available. We propose an evolutionary framework for deconvolving data from a single genome-wide experiment to infer the composition, abundance and evolutionary paths of the underlying cell subpopulations of a tumor. We have developed an algorithm (TrAp) for solving this mixture problem. In silico analyses show that TrAp correctly deconvolves mixed subpopulations when the number of subpopulations and the measurement errors are moderate. We demonstrate the applicability of the method using tumor karyotypes and somatic hypermutation data sets. We applied TrAp to Exome-Seq experiment of a renal cell carcinoma tumor sample and compared the mutational profile of the inferred subpopulations to the mutational profiles of single cells of the same tumor. Finally, we deconvolve sequencing data from eight acute myeloid leukemia patients and three distinct metastases of one melanoma patient to exhibit the evolutionary relationships of their subpopulations.
Optimized strategy for integrated traffic and transit signal control (2008)

This paper proposes a unique and innovative approach to integrate transit signal priority control into a traffic adaptive signal control strategy. The proposed strategy was named OSTRAC (Optimized Strategy for integrated TRAffic and TRAnsit signal Control). The cornerstones of OSTRAC include an online microscopic traffic f low prediction model and a Genetic Algorithm (GA) based traffic signal timing module. A sensitivity analysis was conducted to determine the critical GA parameters. The developed traffic f low model demonstrated reliable prediction results through a test. OSTRAC was evaluated by comparing its performance to three other signal control strategies. The evaluation results revealed that OSTRAC efficiently and effectively reduced delay time of general traffic and also transit vehicles.
Design for assembly, resource and motion planning in the Robcad Open System Environment (ROSE) (1992)

info:eu-repo/semantics/published
Polymorphisms in the CYP1A1 gene are associated with prostate cancer risk (2003)

CYP1A1 is likely to play an important role in the etiology of CaP through its function in activating environmental procarcinogens and catalyzing the oxidative metabolites of estrogens. To test the hypothesis that genetic polymorphisms in the CYP1A1 gene may be associated with the risk for CaP, we compared the allele, genotype and haplotype frequencies of 3 SNPs (3801T>C, 2455A>G and 2453C>A) of CYP1A1 among 159 HPC probands, 245 sporadic CaP cases and 222 unaffected men. Two SNPs (3801T>C and 2455A>G) were each individually associated with CaP risk when the allele and genotype frequencies were compared between CaP patients and unaffected controls. Furthermore, a combined SNP analysis using a haplotype approach revealed an even stronger association in Caucasians. Specifically, 4 major haplotypes (T-A-C, C-A-C, C-G-C and T-A-A) accounted for 99.8% of all observed haplotypes. These 4 haplotypes correspond to the previously described nomenclature (CYP1A1*1A, CYP1A1*2A, CYP1A1*2B and CYP1A1*4). The frequencies of these 4 haplotypes were significantly different among CaP patients and controls. The haplotype T-A-C (CYP1A1*1A) was significantly associated with increased risk for CaP, and the haplotype C-A-C (CYP1A1*2A) was significantly associated with decreased risk for CaP. These findings suggest that genetic polymorphisms in CYP1A1 may modify the risk for CaP.
Synthesis and Biological Evaluation of Phenylacetyl Derivatives Having Low Central Nervous System Permeability as Potent and Selective M2 Muscarinic Receptor Antagonists. (1998)

A series of phenylacetyl derivatives containing the 5,10-dihydro-11H-dibenzo[b,e,][1,4]diazepin-11-one or 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one skeleton was prepared and evaluated for their binding affinities to muscarinic receptors in vitro and for antagonism of bradycardia, salivation and tremor in vivo. Among them, compounds 56 and 66 had high affinity for M2 muscarinic receptors in the heart (pKi = 8.7 and 8.9, respectively) with low affinity for M3 muscarinic receptors in the submandibular gland. A structure-activity relationship (SAR) study suggested that the high M2 selectivity over the M3 muscarinic receptors of 56 may be attributed to the direction of the carboxamide carbonyl group. In in vivo studies, 56 and 66 antagonized oxotremorine-induced bradycardia in rats on both intravenous and oral administration, and their heart rate increasing effect in dogs with nocturnal bradycardia was about 3-fold greater than that of AF-DX 116. Furthermore, they had almost no influence on oxotremorine-induced tremor in mice, presenting no evidence of central transfer.
Adsorptions of Iso- and Terephthalaldehydes on 3-Aminopropyl-Functionalized SBA-15 with Various Loadings (2013)

Abstract Isophthalaldehyde and terephthalaldehyde (m- and p-benzenedialdehydes, respectively) are adsorbed on 3-aminopropyl-functionalized SBA-15 with loadings of 1.1, 1.4, 1.5, and 1.8 mmol g−1. The data are analyzed by fitting with Langmuir adsorption isotherms. For both isomers, the adsorption capacity gradually increases with increasing loading. In contrast, in the adsorption of the m-isomer, the Langmuir constant considerably increases with loading (by a factor of 8.6), while the increase is limited in the case of p-isomer (by a factor of 1.6). This large difference, which is due to structural isomerism of adsorbate, can be explained by the ease of matching of the two aldehyde functions to 3-aminopropyl groups densely populated on the surface. The adsorption model is supported by the results of IR spectroscopy.
Immunization with outer membrane protein A from Salmonella enterica serovar Enteritidis induces humoral immune response but no protection against homologous challenge in chickens (2012)

Vaccination of poultry is one promising strategy to mitigate Salmonella infection in poultry and, in turn, humans as well. We evaluated the efficacy of outer membrane protein A (OmpA) as a novel vaccine candidate against Salmonella in poultry. Native OmpA purified from Salmonella enterica serovar Enteritidis was mixed with adjuvant and administered intramuscularly to 41-d-old chicks. The vaccinated birds showed no decrease in cecal excretion and tissue colonization compared with the unvaccinated birds after oral challenge with 10(9) cfu of the homologous strain at 28 d postimmunization. However, this vaccination induced an increased level of serum anti-OmpA IgG. Similar results were obtained in the replication experiments using a recombinant OmpA with single and double doses. For the development of more effective component vaccines for avian salmonellosis, the vaccine efficacy of outer membrane proteins other than OmpA and route of immunization other than parenteral administration should be evaluated with regard to protection and immune responses, including mucosal IgA.
Effects of Multi-Stage Coupling and Disk Flexibility on Mistuned Bladed Disk Dynamics (2001)

The effects of disk flexibility and multi-stage coupling on the dynamics of bladed disks with and without blade mistuning are investigated. Both free and forced responses are examined using finite element representations of example single- and two-stage rotor models. The reported work demonstrates the importance of proper treatment of interstage (stage-to-stage) boundaries in order to yield adequate capture of disk-blade modal interaction in eigenfrequency veering regions. The modified disk-blade modal interactions resulting from interstage-coupling-induced changes in disk flexibility are found to have a significant impact on (a) tuned responses due to excitations passing through eigenfrequency veering regions, and (b) a design’s sensitivity to blade mistuning. Hence, the findings in this paper suggest that multi-stage analyses may be required when excitations are expected to fall in or near eigenfrequency veering regions or when the sensitivity to blade mistuning is to be accounted for. Conversely, the observed sensitivity to disk flexibility also indicates that the severity of unfavorable structural interblade coupling may be reduced significantly by re-designing the disk(s) and stage-to-stage connectivity. The relatively drastic effects of such modifications illustrated in this work indicate that the design modifications required to alleviate veering-related response problems may be less comprehensive than what might have been expected.
An ACE2-IgG4 Fc Fusion Protein Demonstrates Strong Binding to All Tested SARS-CoV-2 Variants and Reduced Lung Inflammation in Animal Models of SARS-CoV-2 and Influenza (2022)

G921 data are consistent with both antiviral and anti-inflammatory modes of action. G921 is a novel approach for the prevention and treatment of COVID-19 and possible other diseases characterized by deficiency of ACE2.
Taxidermie : la mort dans l’art (2015)

info:eu-repo/semantics/published
Radiographic Image‐Enhancing Agents (2005)

This chapter contains section titled: Conventional Radiography Cardiovascular System Central Nervous System Gastrointestinal System Hepatobiliary System Monocytes and Macrophages Renal System Reproductive System Computed Tomography (CT) Radiography Image-Enhancing Agents Cardiovascular System Central Nervous System Gastrointestinal System Hepatic System Inflammation and Sepsis Lymph Nodes and Lymphatics Neoplasia Renal System Respiratory System Technique Fluoroscopic Imaging
The mutual exclusion problem for unreliable processes: Preliminary report (1976)

Cons,ider;, proces.ses operating asynchronously in parallel, each of whiCh maintains I single &amp;quot;special &amp;quot; variable whichc&amp;quot;n be read (but not written). by the other proce$ses ~ All coordination between processes is to.be accomplished by means of the execution. 6.f. &amp;quot;the primitive operations of a process (ll reading another process&amp;apos;s spedalvariable, and.(2)&amp;apos; seUing.its own spedal variable to ·some. value. A process may &amp;quot;die &amp;quot; at any time,. when its spedal variable is (automatically) set to a special &amp;quot;dead &amp;quot; value. A dead process may revive.. Reading a special variable which is being simultaneously written returns either the old or the new value. Each process may be in a certain &amp;quot;critical &amp;quot; state (which it leaves if it dies). We present a coordination &amp;apos; scheme with the following proper,jies. a time. (1) At most one process is ever in its critical state at (2) If a process wants to enter its critical state, it may do so before any other process enters itscrttical state more than once. (3) The special variables are bounded in value. (4) Some process wanting to (!nter its critical state can always make progress to that g.oal. By the definition of the problem, no process can prevent another from entering its critical state by repeatedly failing and restarting. I n the case of two processes, what makes our solution of particular interest is its remarkable simpli~ity when compared with the extant solutions to this problem. Our n-process solution uses the two-process solution as a subroutine. and is not quite as. elegant as the two-process solution.
Physicochemical properties and isomerization activity of chlorinated Pt/Al2O3 catalysts (1986)

Alumina-supported platinum catalysts with various metal contents have been prepared and chlorinated by CCl4 at 473 and 573 K. Their acidity has been measured by pyridine adsorption and catalytic activity in n-butane isomerization. The state of platinum has been followed by infrared spectroscopy, whereas the modifications of the dispersion were measured by electron microscopy and by H2–O2 titrations.The presence of metal in chlorinated alumina produces only small changes in acidity but a great enhancement in isomerization activity for samples chlorinated at 573 K. After chlorination, platinum is oxidized to platinum chloride, which reacts with AlCl3 to produce the PtCl2·2AlCl3 complex. This complex is mobile on the support and agglomerates in large particles. During the isomerization of n-butane, platinum is reduced in the metallic state leading to very low metal dispersion. Very small platinum clusters are also present, they are able to perform the hydrogenation of butenes and to decrease the coke formation. Thus ageing is limited in comparison with pure alumina. The possible role of HCl leading to superacid species is also discussed.
Prostaglandin E2 involvement in mammalian female fertility: ovulation, fertilization, embryo development and early implantation (2018)

It has been shown that PGE2 positively affects different stages of female fertility. Therefore, PGE2 should be taken into consideration when optimizing reproduction in infertile females. We suggest that in clinical practice, the administration of non-steroidal anti-inflammatory drugs, which are PGE2 synthesis inhibitors, should be reasonable and limited in infertile women. Additionally, assessments of PGE2 protein and receptor expression levels should be taken into consideration.