gebhart/patrepeval huggingface dataset:
Prevalence of selected infectious disease agents in stray cats in Catalonia, Spain (2016)

This study documents that shelter cats in Catalonia are exposed to many infectious agents with clinical and zoonotic significance, and that flea control is indicated for cats in the region.
Bioremediation of hydrocarbon pollution using biosurfactant producing oil degrading bacteria (2002)

A study was undertaken to investigate the distribution of biosurfactant producing, oil degrading bacteria in the oil-contaminated environment. Among 32 oildegrading bacterial isolates 80% exhibited biosurfactant production. They belonged to the genera A4icrococcus, Bacillus, Cotynebacterium, Flavobacterium, Pseudomonas, Acinetobacter, Moroxella and jlavobacterium, They emulsified xylene, benzene, hexane, crude oil, kerosene, gasoline, diesel and olive oil for various degrees. The first five of the above had highest emulsification activity and crude oil degradation ability and therefore were selected for the preparation of mixed consortium for bioremediation studies, Close inspection of the most efficient culture Pseudomonas sp, DS10-129 showed a maximum of 7.5 gl-l rhamnolipid type biosurfactant which resulted in surface tension reduction in the culture broth from 68mN m“’ to 29mN m-l at 84 h incubation. Mass spectrometry examination revealed the presence of both mono and dirhamnolipids (both Rha-Clo-CIOand Rha-Rha-Clo-C1o),The biosurfactant producing isolates had a broad spectrum of emulsification activity with a range of hydrocarbon compounds. The potential of their use in oil bioremediation is discussed.
Phase Partitioning Methods for I/O Cache Optimization (2012)

System designers face large challenges in the storage hierarchy when putting new optimizations into practice. We consider a recent storage cache optimization, designed to reduce cache requirements and boost I/O performance, which adapts to individual program behavior. This scheme leverages a quantum-based design, and we observe that the choice of time quanta has a significant effect on performance and overheads. Accordingly, intelligent designs must judiciously select re-optimization points. We therefore develop new phase detection schemes that identify valued re-optimization points through interaction models between applications and this caching technique. We evaluate online and offline variants in the context of enterprise I/O workloads and observe hit-rate gains over 20% for a range of cache sizes.
Glycosylation deficiency of lipopolysaccharide-binding protein and corticosteroid-binding globulin associated with activity and response to treatment for rheumatoid arthritis (2020)

This study enables to observe that glycosylation changes of CBG and LBP are related to RA disease activity and its response to treatment.
Adaptive torque control of electro-rheological fluid brakes used in active knee rehabilitation devices (2006)

This paper describes the development of an adaptive nonlinear PI torque control for electro-rheological fluid (ERF) based variable resistance brakes that are used in compact and portable rehabilitation devices. The electrorheologic fluid (ERF) brake concepts are introduced and previous work performed with a non-linear PI control on ERFs is tested and analysed. The response of ERF brake systems to this non-linear PI torque control, that utilizes an inverse model, is enhanced through the addition of two key components, a step logic function and an adaptable B-spline based algorithm. The description of each is provided along with tests verifying their effectiveness. In addition, the controller's response to disturbances is provided. The effectiveness of the control is validated through testing on two different electro-rheological fluid based brakes
Effect of dopants in the spin-on glass layer on the bandgap shift in GaAs/AlGaAs and InGaAs/AlGaAs intermixed quantum wells (2005)

Impurity free vacancy disordering (IFVD) is induced in both GaAs/AlGaAs and InGaAs/AlGaAs QWs using undoped, Ga-doped and P-doped spin-on glass encapsulant layers. IFVD has been studied for different annealing and pre-baking temperatures, using low temperature photoluminescence (PL). The P-doped and undoped silica layers behave similarly in promoting IFVD, inducing large energy shifts. The Ga-doped silica layer suppresses IFVD, which is explained by the reduction of Ga outdiffusion from the QW structure into the oxide layer.
Regulation of multidrug resistance 1 expression by CDX2 in ovarian mucinous adenocarcinoma (2016)

Epithelial ovarian cancer is an aggressive gynecological malignancy with a high mortality rate. Resistance against chemotherapeutic agents often develops in ovarian cancer patients, contributing to high recurrence rates. The multidrug resistance 1 (MDR1/ABCB1) gene encodes P-glycoprotein, which affects the pharmacokinetic properties of anticancer agents. We previously reported that the Caudal-related homeobox transcription factor CDX2 transcriptionally regulates MDR1 expression in colorectal cancer. CDX2 is a factor that influences cancer cell differentiation, malignancy, and cancer progression. We hypothesized that profiling of CDX2 and MDR1 expression could be an effective strategy for predicting anticancer drug resistance. We studied the expression of these factors in clinical samples from ovarian cancer patients. We found that endogenous MDR1 expression was positively associated with CDX2 expression in ovarian mucinous adenocarcinoma. Using ovarian mucinous adenocarcinoma cell lines, we also observed decreased MDR1 expression following inhibition of CDX2 by RNA interference. In addition, CDX2 overexpression in MN-1 cells, which display low endogenous CDX2, resulted in upregulation of MDR1 expression. CDX2 induced MDR1-dependent resistance to vincristine and paclitaxel, which was reversed by treatment with the MDR1-specific inhibitor verapamil. Our findings show that CDX2 promotes upregulation of MDR1 expression, leading to drug resistance in ovarian mucinous adenocarcinoma. Therefore, our study demonstrates the potential of novel chemotherapy regimens based on CDX2 status and MDR1 expression in ovarian mucinous adenocarcinoma.
Fabrication and performance of 40-60 MHz annular arrays (2004)

The fabrication and performance of miniature high frequency (40-60 MHz) annular arrays is described. The arrays were fabricated using photolithography to define the electrode pattern, and ultrasonic wire bonding to make electrical contacts. The transducers were 2 mm in diameter with seven equal area elements and a centre frequency of 50 MHz. A -6 dB two-way beam width of 75 microns was found at f/2. The radiation pattern decreased smoothly to less than -60 dB at a distance of 550 microns.
N-Methyl-N,N,N-trioctylammonium chloride as a novel and green corrosion inhibitor for mild steel in an acid chloride medium: electrochemical, DFT and MD studies (2017)

In the present work, <italic>N</italic>-methyl-<italic>N</italic>,<italic>N</italic>,<italic>N</italic>-trioctylammonium chloride (Aliquat 336) has been evaluated as a green and novel corrosion inhibitor for mild steel in a 1 M HCl solution.
The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease (2017)

Abstract Chronic graft-versus-host disease (GVHD) is the leading cause of late, nonrelapse mortality and disability in allogeneic hematopoietic cell transplantation recipients and a major obstacle to improving outcomes. The biology of chronic GVHD remains enigmatic, but understanding the underpinnings of the immunologic mechanisms responsible for the initiation and progression of disease is fundamental to developing effective prevention and treatment strategies. The goals of this task force review are as follows: •Summarize the current state of the science regarding pathogenic mechanisms of chronic GVHD and critical knowledge gaps. •Develop working hypotheses/overriding concepts for chronic GVHD development. •Define the usefulness of current preclinical models to test working hypotheses and ultimately discover and develop new therapeutic strategies. •Identify shortcomings of preclinical models, and define criteria for the creation of additional models to address these limitations. This document is intended as a review of our understanding of chronic GVHD biology and therapies resulting from preclinical studies, and as a platform for developing innovative clinical strategies to prevent and treat chronic GVHD.
The Bone Morphogenetic Proteins Antagonist Noggin Inhibits Membranous Ossification (2001)

Bone morphogenetic proteins (BMPs) are expressed and secreted during fracture repair. Although they are likely to be required for this process, little is known about their physiological role in bone regeneration. Noggin is a protein that specifically binds and inactivates several BMPs. It plays fundamental roles during early embryonal development and limb morphogenesis by this BMP-inactivating activity. This study shows that Noggin can modify bone formation in vivo in the adult animal and, thus, indirectly, that BMP signaling is indispensable in this process. A noggin mutein (hNgdeltaB2-Fc) engineered so as to display increased bioavailability was used. Bilateral titanium bone chambers were inserted in 70 rats, and side comparisons for bone formation in the chambers were done. The hNgdeltaB2-Fc had no effect on total amount of tissue formed in the chamber but decreased the amount of bone compared with both buffer controls and a control made up of an Fc-tagged IL-6Ralpha protein, which had no effects of its own. Also, wild-type noggin inhibited bone formation. Thus, endogenous BMP signaling is necessary for normal bone regeneration.
The systems of the active rigidity and their application in transport machine (2018)

The current state in the field of designing of mechanical systems is characterized by the application of an exhaustively complete set of traditional ways to increase rigidity, that contains the further growth of their principal specifications. Use of high-strength materials only aggravates a problem as their work is supposed at more high tensions, and, therefore, and larger sizes of elastic deformations. At the same time the modern breakthrough technologies in the field of automatic control allow to solve problems, the bound to a slackness of mechanical systems means of operating control of geometrical deviations and fluctuations, and their fissile suppression.
A Church-Rosser theorem for graph grammars (1975)

article Free Access Share on A Church-Rosser theorem for graph grammars Author: Barry K. Rosen IBM Thomas J. Watson Research Center, Yorktown Heights, New York IBM Thomas J. Watson Research Center, Yorktown Heights, New YorkView Profile Authors Info & Claims ACM SIGACT NewsVolume 7Issue 3Summer 1975 pp 26–31https://doi.org/10.1145/1008343.1008344Online:01 July 1975Publication History 14citation177DownloadsMetricsTotal Citations14Total Downloads177Last 12 Months4Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
A suburethral sling procedure with polytetrafluoroethylene for the treatment of genuine stress incontinence in patients with low urethral closure pressure (1989)

One indication for suburethral sling procedures has been recurrent genuine stress incontinence after previous incontinence surgery. Patients with low urethral closure pressures (20 cm H2O or less) in association with genuine stress incontinence are at particular risk for failure of standard anti-incontinence procedures. Urodynamic evaluation was used to select 17 patients with genuine stress incontinence and low urethral closure pressures for surgical treatment with a sling procedure using polytetrafluoroethylene. The technique of the procedure, cure rate, and postoperative complications were assessed. An 85% subjective and objective cure rate was found on urodynamic testing three months postoperatively. Complications included wound seroma, urinary tract infection, and urinary retention.
WebCon: design and modeling of database driven hypertext applications (2003)

As the Web has evolved from its origins as a simple delivery mechanism to a platform for complex applications, the connection of databases and the Web has become more and more important. The design process for a database driven hypertext application is usually divided into modeling of the database and modeling of the hypertext structure. In most of these applications information content is stored within the database, while the hypertext structure is located outside the database system in flat files. This leads to inconsistencies, labor-consuming maintenance and unsatisfying scalability. We present the WebCon approach which uses a traditional data model for storing both the application domain and the hypertext structure. A special repository is introduced for handling meta data which describes the hypertext structure of an application. We implemented a set of universal templates for creating HTML pages out of database contents based on the WebCon repository. The main benefits of WebCon are scalability, high consistency, easy maintenance and rapid prototyping.
Epinephrine Infusion in the Evaluation of Unexplained Cardiac Arrest and Familial Sudden Death (2012)

Epinephrine challenge provoked abnormalities in a substantial proportion of patients, most commonly a prolonged QT interval. Exercise and genetic testing replicated the diagnosis suggested by the epinephrine response in a small proportion of patients. Epinephrine infusion combined with exercise testing and targeted genetic testing is recommended in the workup of suspected familial sudden death syndromes. Clinical Trial Registration- URL: http://www.clinicaltrials.gov. Unique identifier: NCT00292032.
Bi2Mn4O10: a new mullite-type anode material for lithium-ion batteries (2018)

The low specific capacity of graphite limits the further increase of the energy density of lithium-ion batteries and their widespread applications. Exploring new anode materials is the key issue. Herein, a new mullite-type compound Bi2Mn4O10 is designed and synthesized. The Bi2Mn4O10/C composite delivers a high reversible specific capacity of 846 mA h g-1 (more than twice that of graphite), and exhibits a high capacity retention of 100% after 300 cycles at 600 mA g-1, which is reported for the first time. The high specific capacity originates from the combination of the conversion reaction and alloying-dealloying reaction, which has been confirmed by the ex situ XRD, IR, SEM and TEM studies. In addition, the unique nanocomposite generated during the charge-discharge process provides excellent cycling stability. This work proves that Bi2Mn4O10/C is a potential anode material for advanced lithium-ion batteries.
The Impact of Computer and Imaging Technology on Stereotactic Surgery (1987)

Computers, particularly medical imaging techniques, have created a renaissance in stereotactic surgery. Human stereotaxis was primarily developed and performed beginning in the 1940s for functional disorders. Interest waned in the 1960s following the introduction of L-dopa until computer-based three-dimensionally precise tomographic modalities (specifically computed tomography) were introduced beginning in the mid-1970s as a routine diagnostic aid. New image-compatible hardware and instrumentation were introduced along with techniques and associated software for relating points and volumes appearing on these diagnostic images into stereotactic space. This paper reviews the computer and imaging technology that has led to this renaissance and discusses some of the important features of a computer-interactive stereotactic system.
Practical homomorphic encryption: A survey (2014)

Cloud computing technology has rapidly evolved over the last decade, offering an alternative way to store and work with large amounts of data. However data security remains an important issue particularly when using a public cloud service provider. The recent area of homomorphic cryptography allows computation on encrypted data, which would allow users to ensure data privacy on the cloud and increase the potential market for cloud computing. A significant amount of research on homomorphic cryptography appeared in the literature over the last few years; yet the performance of existing implementations of encryption schemes remains unsuitable for real time applications. One way this limitation is being addressed is through the use of graphics processing units (GPUs) and field programmable gate arrays (FPGAs) for implementations of homomorphic encryption schemes. This review presents the current state of the art in this promising new area of research and highlights the interesting remaining open problems.
Peace and the New World Order (1999)

Abstract With the end of World War II in sight, Republicans in Spain began to concert their efforts to engage international support for their cause. In the United States, Rep. John Coffey had tried unsuccessfully before to get Congress on record in support of an immediate break with Francisco Franco. With the Yalta Conference imminent, the new United States Secretary of State, Edward Stettinius, had many considerations to bear in mind in relation to future policy towards Spain, though little time to consider any of them. The main difficulty in formulating a coherent post-war foreign policy towards Spain which would be acceptable to public opinion arose from war-time propaganda run by the Office of War Information. As peace approached, little underlined the differences in Spanish policy between Britain and the United States more clearly than their diametrically opposed requirements of Argentina.
Field Application of a New Cleanable and Damage Tolerant Downhole Screen (1995)

ABSTRACT This paper describes an alternative technology to conventional wire wrapped and prepacked screens. In this new screen, multiple and independent layers of a permeable stainless steel composite material are sandwiched between a perforated base pipe and an external armored cage. Advantages of this design include: 1) even extreme mechanical deformations do not affect the screen's sand retention; 2) an all-metallic construction eliminates the deficiencies common to prepacked screens (loose sand packing, eccentric prepack annulus, chemical incompatibilities with resin coatings, cracking of resin coated prepacks); 3) its compact construction results in a small OD that extends its range down to small diameters for through tubing gravel packs and gravel pack repairs. These advantages have been substantiated by laboratory tests and field installations. The results of these tests are presented in this paper.
Morphine Potentiates the Gastroulcerogenic Effect of Indometacin in Rats (1985)

Morphine potentiated the ulcerogenic activity of indometacin in a dose-dependent manner when administered subcutaneously (2.5-7.5 mg/kg). However, in the case of intracerebroventricular administration, morphine failed to exert any potentiating action. Atropine (0.5 mg/kg, s.c.) and cimetidine (12.5-25 mg/kg, s.c.) decreased the ulcerogenic activity of indometacin, and the combination of indometacin/morphine in about the same degree. However, the reduced ulcerogenic activity of indometacin after atropine or cimetidine treatment could still be enhanced by morphine if it was added to the combination of indometacin/atropine or indometacin/cimetidine. Since the potentiating action of morphine was completely blocked by naloxone (1 mg/kg), this action of morphine might be mediated via opiate receptors.
Monitoring of velocity and pressure fields within an axial turbine (2010)

In the framework of the consortium of R&D on hydraulic machines launched by the LAMH (Hydraulic Machines Laboratory of Laval University) in November 2007, a five holes unsteady pressure probe using embedded pressure sensors has been developed. Such probe allows us to obtain the unsteady static pressure, total pressure and the three flow velocity components. This paper aims to present this new five holes unsteady pressure probe, used and results for a propeller turbine.
Tubacin Kills Epstein-Barr Virus (EBV)-Burkitt Lymphoma Cells by Inducing Reactive Oxygen Species and EBV Lymphoblastoid Cells by Inducing Apoptosis (2009)

Tubacin is a small molecule inhibitor of histone deacetylase 6 and blocks aggresome activity. We found that Epstein-Barr virus (EBV)-positive Burkitt lymphoma (BL) cells were generally killed by lower doses of tubacin than EBV-transformed lymphoblastoid cells (LCLs) or EBV-negative BL cells. Tubacin induced apoptosis of LCLs, which was inhibited by pretreatment with a pancaspase inhibitor but not by butylated hydroxyanisole, which inhibits reactive oxygen species. In contrast, tubacin killed EBV-positive BL cells in a caspase-3-independent pathway that involved reactive oxygen species and was blocked by butylated hydroxyanisole. Previously, we showed that bortezomib, a proteasome inhibitor, induces apoptosis of EBV LCLs and that LCLs are killed by lower doses of bortezomib than EBV-positive BL cells. Here we found that the combination of bortezomib and tubacin acted in synergy to kill EBV-positive BL cells and LCLs. Tubacin or the combination of bortezomib and tubacin did not induce EBV lytic replication. These findings suggest that the combination of a proteasome inhibitor and an HDAC6 inhibitor may represent a useful strategy for the treatment of certain EBV-associated B cell lymphomas.
Nitroglycerin as a Provocative Agent (1968)

IT IS RELATIVELY seldom that the physician has an opportunity to witness an attack of cluster headache (Horton's syndrome). Consequently, the diagnosis generally is based on anamnestic data supplied by the patient. A definite method for provoking an attack would therefore be of value, from both the diagnostic-therapeutic and the pathophysiological aspects, to establish the mechanism of the actual headache. Horton<sup>1-3</sup>showed that subcutaneous injection of histamine can elicit an attack, and reported positive results in 69% of his cases. The corresponding incidence in Peters' series was 75%.<sup>4</sup>Several authors have, however, doubted the value of the histamine test. Thus, Gardner et al<sup>5</sup>found that a typical attack could be precipitated only in the occasional case, and Friedman and Mikropoulos<sup>6</sup>were not convinced of the specificity or value of the test. Although nitroglycerin has been mentioned as a provocative agent in connection with Horton's syndrome,
Bacillus Calmette Guérin (BCG) activates lymphocyte to promote autophagy and apoptosis of gastric cancer MGC-803 cell (2018)

Bacillus Calmette Guérin (BCG) has a potential anti-tumor effect on gastric cancer. However, the mechanism is still unclear. In this study, we investigated the effect of BCG on gastric cancer cell line MGC-803 and studied the potential cooperation of BCG and lymphocyte in determining the final fate of cancer cells. After treatment with BCG, the cell viability was significantly inhibited in a dosage-dependent manner. Flow cytometry assay showed the apoptosis rates were significantly increased by BCG. Using western blot assay, results showed that BCG increased cleaved-caspase-3, LC-3BII and Atg-3. After cocultured with BCG and lymphocyte, the apoptosis rates, the levels of cleaved-caspase-3, and the protein levels of LC-3BII and Atg-3 were significantly increased compared with BCG or lymphocytes alone groups. ELISA detection found that BCG induced secretion of interferon gamma (IFNg) from lymphocytes. BCG with IFNg also increased levels of cleaved-caspase-3, LC-3BII and Atg-3. Taken together, BCG promotes lymphocyte immunocompetence to induce cell apoptosis and autophagy in MGC-803 cells, might through inducing release of IFNg from peripheral blood lymphocytes.