gebhart/patrepeval huggingface dataset:
Automated Tool Chain for Evaluation of Real World Tests Developed and Applied in eCoMove and interactIVe (2013)

This work summarizes the main design characteristics of an automated tool chain to analyze measurement data from real world field trials in order to validate different aspects and functionalities of assistance systems. The highly flexible and adaptable data format as well as corresponding steps in information processing are presented. The approach described is applied in the European research projects eCoMove and interactIVe and hence is adaptable to different requirements on data analysis. As real world test may acquire confidential measurement data the approach ensures that these do not end up in validation results provided to project partners.
Noncoherent turbo decoding (2002)

We propose a new turbo code noncoherent detection scheme based on a novel a-priori probability processor (APP). Using this method, many turbo encoders can be used without a change in the code or in the modulation, and without a significant change in the structure of the iterative decoder. Simulation results of this method are presented for various phase noise levels. We show a degradation of 0.7 dB from the coherent detection of the same codes.
Pathophysiology of cancer cachexia (2000)

Cancer cachexia is a frequent complication observed in patients with malignant tumors. Although several decades have passed since the first focus on the metabolic dysfunction's associated with cancer, few effective therapeutic interventions have been successfully introduced into the medical armamentarium. The present study thoroughly reviews the basic pathophysiology of cancer cachexia and the treatment options already investigated in that field. Experimental and clinical studies were evaluated individually in order to clarify the intricate alterations observed in tumor-bearing patients. The difficulties in introducing sound and effective nutritional support or metabolic manipulation to reverse cancer cachexia are outlined in this review.
In Situ Formation of an Oxygen-Evolving Catalyst in Neutral Water Containing Phosphate and Co 2+ (2008)

The utilization of solar energy on a large scale requires its storage. In natural photosynthesis, energy from sunlight is used to rearrange the bonds of water to oxygen and hydrogen equivalents. The realization of artificial systems that perform "water splitting" requires catalysts that produce oxygen from water without the need for excessive driving potentials. Here we report such a catalyst that forms upon the oxidative polarization of an inert indium tin oxide electrode in phosphate-buffered water containing cobalt (II) ions. A variety of analytical techniques indicates the presence of phosphate in an approximate 1:2 ratio with cobalt in this material. The pH dependence of the catalytic activity also implicates the hydrogen phosphate ion as the proton acceptor in the oxygen-producing reaction. This catalyst not only forms in situ from earth-abundant materials but also operates in neutral water under ambient conditions.
Model-Based Load Characteristics Analysis of the Multi-Dimensional Force Sensor (2019)

As an important component of force feedback device, multi-dimensional force sensor has been widely used in haptic device, prosthetic hand and other devices. In a given application, the multi-dimensional force sensor is always coupled with a load by the screw thread, which may result in a totally different dynamic behavior from a bare force sensor. It is the key data for deeply understanding the dynamic performance to have information about the structural distribution of stiffness and mass of the multi-dimensional force sensor. To address this need, the approach of model-based load characteristic analysis of the multi-dimensional force sensor is presented in this paper. Dynamic behavior of the force sensor in a given load is described by a lumped mass model consists of spring-mass-damper elements and characterized by the model parameters that describe the dynamic correlation distribution of mass, stiffness, and damping. The main purpose of the proposed approach is the description of the load characteristics of the multi-dimensional force sensor, independent of the given mechanical environment, which provides a certain theoretical reference for the calculation of the load capacity of the force sensor.
Glucose-6-Phosphate Dehydrogenase Deficiency: An Etiology for Idiopathic Priapism? (2007)

G6PD deficiency offers an explanation for idiopathic priapism. The medical condition generates a pathophysiologic milieu consistent with aberrant NO signaling and heightened oxidative stress in the penis.
Cross-Cultural User-Experience Design: What? So What? Now What? (2005)

 Modern technology and commerce permit global distribution of products, services  User diversity: Ever increasing variety of group demographics and individual needs/wants  Traditional user-interface design and usability disciplines: Improve performance and productivity  User-experience (UX) design issues: Even more complex and challenging  Culture analysis offers a way to understand, even measure, differences and similarities of UX Aaron Marcus and Associates, Inc., www.AMandA.com, 4 AM+A
Supplementary Figure from Intronic <i>Cis-</i>Element DR8 in <i>hTERT</i> Is Bound by Splicing Factor SF3B4 and Regulates <i>hTERT</i> Splicing in Non–Small Cell Lung Cancer (2023)

Supplementary Figure from Intronic &lt;i&gt;Cis-&lt;/i&gt;Element DR8 in &lt;i&gt;hTERT&lt;/i&gt; Is Bound by Splicing Factor SF3B4 and Regulates &lt;i&gt;hTERT&lt;/i&gt; Splicing in Non–Small Cell Lung Cancer
Variations in the magneto-optic coupling coefficient in a bismuth-lutetium-iron-garnet film (1996)

Magnetostatic wave-optical interactions are studied in the transverse geometry using a [BiLu]/sub 3/Fe/sub 5/O/sub 12/ film. Non-monotonic variations in the magneto-optic coupling coefficient are observed as we increase the input microwave power at a fixed frequency. Similar variations are also seen in the transmitted microwave signal, though the features appear at higher power levels. The non-monotonic behavior is due to a shift in the microwave passband with increasing power. Density plots are used to correlate the two sets of data over a 350 MHz region. The discrepancy in power levels associated with a feature in the line plots is a consequence of the different curvatures of the two density plots.
Hopfield neural network based algorithms for image restoration and reconstruction. II. Performance analysis (2000)

For pt. I see ibid., vol.48, no.7, p.2105-18 (2000). In this paper, we analyze four typical sequential Hopfield (1982) neural network (HNN) based algorithms for image restoration and reconstruction, which are the modified HNN (PK) algorithm, the HNN (ZCVJ) algorithm with energy checking, the eliminating-highest-error (EHE) algorithm, and the simulated annealing (SA) algorithm. A new measure, the correct transition probability (CTP), is proposed for the performance of iterative algorithms and is used in this analysis. The CTP measures the correct transition probability for a neuron transition at a particular time and reveals the insight of the performance at each iteration. The general properties of the CTP are discussed. Derived are the CTP formulas of these four algorithms. The analysis shows that the EHE algorithm has the highest CTP in all conditions of the severity of blurring, the signal-to-noise ratio (SNR) of a blurred noisy image, and the regularization term. This confirms the result in many previous simulations that the EHE algorithms can converge to more accurate images with much fewer iterations, have much higher correct transition rates than other HNN algorithms, and suppress streaks in restored images. The analysis also shows that the CTPs of all these algorithms decrease with the severity of blurring, the severity of noise, and the degree of regularization, which also confirms the results in previous simulations. This in return suggests that the correct transition probability be a rational performance measure.
Cervicogenic Headache (2022)

Abstract This chapter focuses on cervicogenic headache, a secondary headache disorder in which pain is referred to the head from a source in the cervical spine. It can be challenging to diagnose, in part because neck pain may not be a prominent part of the presentation. One diagnosis which should not be missed is dissection of the vertebral or internal carotid arteries, which can present with neck pain and/or headache. Lesions in the posterior cranial fossa should be eliminated as well. Diagnostic imaging of the cervical spine may be helpful in some cases, although is often not necessary in diagnosing cervicogenic headache. For probable cervicogenic headache, or in circumstances in which diagnostic blocks are not an option, exercises with or without manual therapy seem to be the best options among conservative therapy. Pharmacological treatments are not well established, but neuropathic pain medications, tricyclic antidepressants, and muscle relaxants have been employed.
Inter-subunit interactions drive divergent dynamics in mammalian and Plasmodium actin filaments (2018)

Cell motility is essential for protozoan and metazoan organisms and typically relies on the dynamic turnover of actin filaments. In metazoans, monomeric actin polymerises into usually long and stable filaments, while some protozoans form only short and highly dynamic actin filaments. These different dynamics are partly due to the different sets of actin regulatory proteins and partly due to the sequence of actin itself. Here we probe the interactions of actin subunits within divergent actin filaments using a comparative dynamic molecular model and explore their functions using Plasmodium, the protozoan causing malaria, and mouse melanoma derived B16-F1 cells as model systems. Parasite actin tagged to a fluorescent protein (FP) did not incorporate into mammalian actin filaments, and rabbit actin-FP did not incorporate into parasite actin filaments. However, exchanging the most divergent region of actin subdomain 3 allowed such reciprocal incorporation. The exchange of a single amino acid residue in subdomain 2 (N41H) of Plasmodium actin markedly improved incorporation into mammalian filaments. In the parasite, modification of most subunit-subunit interaction sites was lethal, whereas changes in actin subdomains 1 and 4 reduced efficient parasite motility and hence mosquito organ penetration. The strong penetration defects could be rescued by overexpression of the actin filament regulator coronin. Through these comparative approaches we identified an essential and common contributor, subdomain 3, which drives the differential dynamic behaviour of two highly divergent eukaryotic actins in motile cells.
A stable tRNA-like molecule is generated from the long noncoding RNA GUT15 in Arabidopsis (2018)

The Arabidopsis GUT15 RNA belongs to a class of noncoding RNAs that are expressed from the intergenic regions of protein-coding genes. We show that the RNA polymerase II transcribed GUT15 transcript serves as a precursor for two stable RNA species, a tRNA-like molecule and GUT15-tRF-F5, which are both encoded by the final intron in the GUT15 gene. The GUT15-encoded tRNA-like molecule cannot be autonomously transcribed by RNA polymerase III. However, this molecule contains a CCA motif, suggesting that it may enter the tRNA maturation pathway. The GUT15-encoded tRNA-like sequence has an inhibiting effect on the splicing of its host intron. Moreover, we demonstrate that the canonical tRNA genes nested within introns do not affect the splicing patterns of their host protein-coding transcripts.
A robust spring-like lamellar VO/C nanostructure for high-rate and long-life potassium-ion batteries (2020)

A unique spring-like lamellar VO/C nanostructure exhibits excellent stability and outstanding rate capability for potassium-ion batteries.
10W reliable operation of 808nm broad-area diode lasers by near-field distribution control in a multistripe contact geometry (2007)

High-power diode lasers operating at 808 nm and consisting of a multiple ridge-waveguide structure have been fabricated. Lasers with this structure show a more stable far and near field pattern in comparison to conventional single stripe broad area lasers. A reliable continuous wave operation at room temperature over 8000 h at 8 W and 800 h at 10 W has been achieved with 200 &mgr;m stripe width devices.
ABCA3 Expression in AML Blast Cells: Association with Poor Disease Outcome and Intracellular Drug Sequestration. (2006)

Abstract Analysing the intrinsic drug efflux capacity of leukemic stem cell with the side population (SP) phenotype, we recently found the intracellular ABC transporter ABCA3 expressed in blast cells from patients with acute myeloid leukaemia (AML). Here we extend our observations to a larger cohort of AML samples and addressed the role of ABCA3 for cytostatic drug resistance. Applying quantitative RT/PCR (Taqman), we detected significant levels of ABCA3 in 59 of 92 blast cell samples from 58 pediatric and 34 adult patients with AML. The expression of ABCA3 correlated positively (coefficient 0.83) with the expression of CD34, while there was no association with the acquisition of markers for myeloid and monocytic maturation. As for disease outcome analysed by univariate analysis, we found a significantly worse outcome in both event free survival (p=0.048) and overall survival (p=0.034) for the patients with high-level ABCA3 expression. Functionally, the expression of ABCA3 was restricted to the cytoplasm in the AML blast cells, and co-localisation studies revealed an association with endosomal markers. Ectopic expression of ABCA3 augmented the lysosomal compartment in HEK 293 cells, and enhanced intracellular anthracyclin sequestration into vesicles of the endosomal system. Correspondingly, we observed a significant reduction of cytostatic efficacy from anthracyclins in stably ABCA3 expressing HEK293 cells compared to the parental cell line. In conclusion, we found the intracellular transporter ABCA3 expressed in the blast cells of most patients with AML, and elevated ABCA3 levels associated with poor disease outcome. Functional data revealed intracellular anthracyclin sequestration by ABCA3, suggesting a role of ABCA3 for drug resistance in patients with AML.
Nonreciprocal broken ray transforms with applications to fluorescence imaging (2018)

Broken ray transforms (BRTs) are typically considered to be reciprocal, meaning that the transform is independent of the direction in which a photon travels along a given broken ray. However, if the photon can change its energy (or be absorbed and re-radiated at a different frequency) at the vertex of the ray, then reciprocity is lost. In optics, non-reciprocal BRTs are applicable to imaging problems with fluorescent contrast agents. In the case of x-ray imaging, problems with single Compton scattering also give rise to non-reciprocal BRTs. In this paper, we focus on tomographic optical fluorescence imaging and show that, by reversing the path of a photon and using the non-reciprocity of the data function, we can reconstruct simultaneously and independently all optical properties of the medium (the intrinsic attenuation coefficients at the excitation and the fluorescence frequency and the concentration of the contrast agent). Our results are also applicable to inverting BRTs that arise due to single Compton scattering.
Perspectives transfusionnelles des cellules souches: le modèle des globules rouges de culture (2010)

Dans un contexte de difficulte chronique d’approvisionnement en produits sanguins, l’interet de disposer de sources complementaires de globules rouges pour la transfusion sanguine est evident. La mise au point de molecules chimiques ou naturelles qui remplaceraient l’hemoglobine se revele difficile. Le sang artificiel est encore hors d’atteinte. Ainsi, au lieu de remplacer ce que fait la nature, pourquoi ne pas la copier ? Pour ces raisons, tenter de generer des globules rouges dans un laboratoire, fait sens. Nous decrivons ici les recherches en cours qui permettront la generation massive d’hematies humaines a partir de cellules souches hematopoietiques et pluripotentes. Nous faisons le point sur l’etat de l’art de ce concept, evoquons les obstacles a surmonter pour passer du modele de laboratoire a la clinique, et analysons les indications possibles a moyen et long termes. Si elle aboutit, cette nouvelle approche pourrait etre un progres considerable en matiere de transfusion.
Accelerated life studies of polyimide film under electrical and thermal multistress (2003)

Accelerated life studies on a high-temperature polyimide film (Kapton) were conducted under simultaneous electrical and thermal stress at 60 Hz and 400 Hz. The breakdown strength and the aging characteristics were obtained at test temperatures of 23 degrees C, 100 degrees C and 200 degrees C. The two-parameter Weibull distribution was used in the evaluation of the experimental data. The experimental results show that electrical aging, by increasing the applied voltage or the applied frequency, is the mechanism responsible for failure under these conditions, and that thermal aging is not a major degradation factor for the Kapton film in the applied temperature range, particularly at the higher frequency of 400 Hz. Several theoretical models were considered to obtain the best approximation to the experimental data. The analysis shows that present physical models cannot take into account acceleration of aging with the applied frequency.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Experimental and Numerical 3-D Investigations of the Flow Field Behind the Trailing Edge of a Cooled Turbine Guide Vane (1996)

Experimental investigations have been carried out to analyze the hot gas flow and cooling gas flow in the direct vicinity of the trailing edge of a modern gas turbine vane, with cooling gas ejection through the trailing edge. The investigations were performed in one of the institute’s test turbines. The experimental set-up is designed to establish variable blowing ratios between cooling gas mass flow and hot gas mass flow. An alternative density ratio between hot gas and cooling gas was established by the use of CO2 instead of air as the cooling gas for cold test runs. The experimental investigations have been carried out for different radial positions. The measurement plane was located 0.2mm to 0.5mm downstream of the trailing edge (trailing edge width 1.6mm). Local regions of high anisotropic turbulence were detected in the mixing zone. For low blowing ratios, the trailing edge pressure side in the tip vicinity was found to be subjected to direct hot gas contact. The trailing edge ejection has an influence of at least one chordlength in axial direction. The experimental investigations were accompanied by 3-D Navier-Stokes computational simulations. The calculated velocity distributions were found to be quite consistent with the experimental results. The calculated flow angles differed locally from the measurements. This may be due to the turbulence model employed.
Authorization mechanism for MQTT-based Internet of Things (2016)

This paper presents the design and implementation of an authorization mechanism for MQTT-based Internet of Things (IoT). The design is based on OAuth 1.0a, which is an open authorization standard for web applications. Some redesign and modification have been made to the based framework to fit it within the MQTT environment. Several considerations are taken into account, including limited node resources, lack of node's user interface, and key/secret distribution and management. The design is implemented on a real MQTT-based IoT service platform and demonstrated that it works as intended. Authorization delay and message overhead are minimal. Security issues are analyzed along with discussion for future work.
Suppression of Delayed‐type Hypersensitivity and Hemolysis Induced by Previously Photooxidized Psoralen: Effect of Fluence Rate and Psoralen Concentration (1997)

The kinetics of the formation of biologically active psoralen photooxidation (POP) products were analyzed by the biological effects produced. Effects of the UV light fluence rate and psoralen concentration during the preirradiation were investigated to assess the yield of POP products, which were active in vivo (inducing suppression of delayed-type hypersensitivity [DTH] reaction to sheep red blood cells) and in vitro (altering the human erythrocyte membrane permeability). It was shown that the reciprocity law of the irradiation fluence rate and time was not valid in the case of POP-induced hemolysis and DTH suppression. Immunosuppressive POP products were more efficiently formed at low fluence rate (20.8 W/m2), whereas POP hemolysins were more efficiently produced at a high fluence rate (180 W/m2) of UV light. The yield of immunosuppressive POP products was enhanced in dilute psoralen solutions, while the POP hemolysins yield increased with increasing psoralen concentration. A kinetic scheme for psoralen photoproduct formation was proposed. Kinetic analysis showed that a labile intermediate was produced as the result of excitation of psoralen. This intermediate was either converted to a stable immunosuppressive POP product, or two intermediates combined to form a POP hemolysin. It is proposed that PUVA therapy conditions are more favorable for the formation of immunosuppressive rather than membrane-damaging psoralen photooxidation products.
Construction of lactose-utilizing Xanthomonas campestris and production of xanthan gum from whey (1990)

Xanthomonas campestris pv. campestris possesses a low level of beta-galactosidase and therefore is not able to grow and produce significant amounts of xanthan gum in a medium containing lactose as the sole carbon source. In this study, a beta-galactosidase expression plasmid was constructed by ligating an X. campestris phage phi LO promoter with pKM005, a ColE1 replicon containing Escherichia coli lacZY genes and the lpp ribosome-binding site. It was then inserted into an IncP1 broad-host-range plasmid, pLT, and subsequently transferred by conjugation to X. campestris 17, where it was stably maintained. The lacZ gene under the control of the phage promoter was expressed at a high level, enabling the cells to grow in a medium containing lactose. Production of xanthan gum in lactose or diluted whey by the engineered strain was evaluated, and it was found to produce as much xanthan gum in these substrates as the cells did in a medium containing glucose.
Real time task manager for communications and control in multicar platoons (2003)

Present and future automated intelligent vehicle/highway systems (IVHS) require cooperation and communication between vehicles on the road. An IVHS system can be divided into four layers of control. The regulation layer executes control algorithms that actuate throttle, braking, and/or steering. The regulation layer receives commands from the platoon layer which plans maneuvers such as merging vehicles into a platoon, splitting a platoon of vehicles, and lane changes. The link layer may assign a platoon speed and size. This layer and a higher layer, the network layer, are implemented in roadside computers. The focus of this paper is on the regulation and platoon layers. A protocol is proposed to allow the exchange of messages by vehicles performing co-operative maneuvers. The protocol assumes that all of the interacting vehicles have access to a single radio channel. Data is transmitted in frames that are divided into two channels: a synchronous channel used for round robin transmissions or receptions of data, and a contention channel used to exchange messages of the platoon layer. The synchronous channel is used to transmit or receive speed and acceleration of each vehicle between its neighbors. The test and implementation of the protocol on an automatically controlled platoon to maintain longitudinal control is described. This paper presents another design of a communication task for multicar platoons and a C-language implementation.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>