gebhart/patrepeval huggingface dataset:
Web Mining and Knowledge Discovery of Usage Patterns (2001)

Web mining is a very hot research topic which combines two of the activated research areas: Data Mining and World Wide Web. The Web mining research relates to several research communities such as Database, Information Retrieval and Artificial Intelligence. Although there exists quite some confusion about the Web mining, the most recognized approach is to categorize Web mining into three areas: Web content mining, Web structure mining, and Web usage mining. Web content mining focuses on the discovery/retrieval of the useful information from the Web contents/data/documents, while the Web structure mining emphasizes to the discovery of how to model the underlying link structures of the Web. The distinction between these two categories isn&amp;apos;t a very clear sometimes. Web usage mining is relative independent, but not isolated, category, which mainly describes the techniques that discover the user&amp;apos;s usage pattern and try to predict the user&amp;apos;s behaviors.
Wireless Communication in Orienteering (2005)

Orienteering is a popular competition where the participants have to pass by a number of control points in numerical order, and in the fastest time, in order to win. In the current competitions of orienteering, it is very difficult for the public to follow the race due to the fact that these competitions are carried out in forests. In this project, we apply ad-hoc network to this scenario so that the control points send the information of each participant to a main server, in a multihop way, in order to show the information to the public. The goals are to save power and decrease the delay. This project studies the main MAC protocols for ad-hoc, and compares both of the main branches: contention-based and TDMA, by measuring the sleeping time and the delay in different networks, always with the orienteering scenario in mind. Even though TDMA reaches better efficiency, because of being simpler, a final solution based on contention-based has been implemented that works
Cationic surface active agents as fabric softeners (1978)

Abstract Rinse cycle, wash cycle, and dryer type softeners are reviewed and their compositions discussed. Ashland’s conclusions are: (a) Rinse cycle softeners give the best performance from a softening and anti‐static point of view. They are, however, less convenient to use since they must be introduced into the final rinse, (b) Wash cycle softeners are convenient to use, but higher use levels are necessary to impart adequate softening and anti‐static properties making their use more expensive. They also tend to decrease the cleaning properties of the detergent used, (c) Dryer type softeners are convenient to use, but they impart less softening because of nonuniform deposition of softener on the fabric. The anti‐static properties, on the other hand, imparted by these softeners are very good.
A Network-Based Method to Assess the Statistical Significance of Mild Co-Regulation Effects (2013)

Recent development of high-throughput, multiplexing technology has initiated projects that systematically investigate interactions between two types of components in biological networks, for instance transcription factors and promoter sequences, or microRNAs (miRNAs) and mRNAs. In terms of network biology, such screening approaches primarily attempt to elucidate relations between biological components of two distinct types, which can be represented as edges between nodes in a bipartite graph. However, it is often desirable not only to determine regulatory relationships between nodes of different types, but also to understand the connection patterns of nodes of the same type. Especially interesting is the co-occurrence of two nodes of the same type, i.e., the number of their common neighbours, which current high-throughput screening analysis fails to address. The co-occurrence gives the number of circumstances under which both of the biological components are influenced in the same way. Here we present SICORE, a novel network-based method to detect pairs of nodes with a statistically significant co-occurrence. We first show the stability of the proposed method on artificial data sets: when randomly adding and deleting observations we obtain reliable results even with noise exceeding the expected level in large-scale experiments. Subsequently, we illustrate the viability of the method based on the analysis of a proteomic screening data set to reveal regulatory patterns of human microRNAs targeting proteins in the EGFR-driven cell cycle signalling system. Since statistically significant co-occurrence may indicate functional synergy and the mechanisms underlying canalization, and thus hold promise in drug target identification and therapeutic development, we provide a platform-independent implementation of SICORE with a graphical user interface as a novel tool in the arsenal of high-throughput screening analysis.
Fast robust subject‐independent magnetoencephalographic source localization using an artificial neural network (2004)

We describe a system that localizes a single dipole to reasonable accuracy from noisy magnetoencephalographic (MEG) measurements in real time. At its core is a multilayer perceptron (MLP) trained to map sensor signals and head position to dipole location. Including head position overcomes the previous need to retrain the MLP for each subject and session. The training dataset was generated by mapping randomly chosen dipoles and head positions through an analytic model and adding noise from real MEG recordings. After training, a localization took 0.7 ms with an average error of 0.90 cm. A few iterations of a Levenberg-Marquardt routine using the MLP output as its initial guess took 15 ms and improved accuracy to 0.53 cm, which approaches the natural limit on accuracy imposed by noise. We applied these methods to localize single dipole sources from MEG components isolated by blind source separation and compared the estimated locations to those generated by standard manually assisted commercial software.
Influence of Chemical Structure on Hydration and Gas Transport Mechanisms of Sulfonated Poly(aryl ether ketone) Membranes (2012)

This work reports the influence of the chemical structure of two sulfonated poly(aryl ether ketone)s (SPAEK) on the hydration and gas transport mechanism of thin membranes made thereupon. For this purpose, two sulfonated poly(aryl ether ketone)s having the same ionic exchange capacity (IEC) but bearing a different repartition of the sulfonic acid groups along the polymer backbone were prepared. These polymers were synthesized by direct copolymerization of two specific sulfonated precursors, bisphenol AF and 4,4′-difluorobenzophenone. The morphology of the membranes was studied by transmission electron microscopy, and the thermal properties of the ionomers were determined from differential scanning calorimetry and thermogravimetric analyses. A detailed analysis of the water sorption isotherms and kinetics was performed. The gas transport properties were also determined for He, H₂, and CO₂ in the full range of water activity. From the detailed analysis of the water sorption isotherm and of the relative contributions of the Fickian diffusion and relaxation phenomena, a water sorption mechanism was proposed in relation with the SPAEK architectures and polymers’ chain mobility. This mechanism allowed explaining the different evolution of the gas transport properties observed as a function of the gas nature and hydration rate.
Abstract B029: Phenylacetaldehyde induces apoptosis through endoplasmic reticulum stress and potentiates the effect of 5-FU treatment in colorectal cancer (2022)

Abstract Introduction: Phenylacetaldehyde (PAA), a product of phenylalanine metabolism, is generated by microbiota and has demonstrated anticancer properties in breast cancer. As intestinal homeostasis is influenced by the gut microbiome, we investigated the effect of PAA on colorectal cancer (CRC). Methods: Serum PAA levels and feces microbiota from a test cohort of 30 CRC patients and 30 healthy control patients were analyzed by targeted GC-MS/MS and metagenomic sequencing. A validation cohort of 75 CRC patients and 53 healthy control patients was analyzed for PAA levels in serum. CRC cell lines and CRC-patient-derived organoids were cultured and treated with PAA alone or in combination with 5-fluorouracil (5-FU), then evaluated for viability, proliferation, cell cycle distribution, and cell death in vitro. The effect of PAA alone or in combination with 5-FU on tumor growth was also tested in vivo. We identified the mechanisms induced by PAA treatment using RNA sequencing, western blot, immunostaining, and ROS quantification assay. Results: PAA levels were significantly decreased in the circulation of CRC patients compared to healthy controls in our study population and the validation cohort. Metagenomic sequencing indicated the bacteria that positively correlated with PAA levels were significantly more abundant in healthy controls; while bacteria that negatively correlated with PAA were more abundant in CRC. In vitro, PAA inhibited the viability and colony formation of CRC cell lines as well as human-derived organoids in a concentration-dependent manner. Mechanistically, PAA treatment induced a P53-dependant G1 cell cycle arrest and cell death in HCT116 and RKO cell lines. An investigation by RNA sequencing and immunoblotting showed that PAA inhibits CRC by inducing endoplasmic reticulum stress-induced autophagy accompanied by downregulation in PI3K/AKT/mTOR and ERK pathways by generating reactive oxygen species. When combined with 5-FU, PAA enhanced the potency of 5-FU on viability, cell death, and cell cycle arrest by inducing DNA damage and tumor growth. Conclusions: The bacteria metabolite PAA increased CRC cell death by endoplasmic reticulum stress-induced autophagy and downregulation of the PI3K/AKT/mTOR and ERK pathways. PAA also potentiated the chemotherapeutic efficacy of 5-FU through induction of DNA damages. These findings warrant further exploration of PAA as a potential CRC biomarker and novel therapeutic agent. Citation Format: Sylvain J. Ferrandon, Cheng Kong, Joseph Fedro, Rami James Nabil Aoun, Zeneng Wang, Chureeporn Chitchumroonchokchai, Huanlong Qin, Steven Clinton, Matthew F. Kalady. Phenylacetaldehyde induces apoptosis through endoplasmic reticulum stress and potentiates the effect of 5-FU treatment in colorectal cancer [abstract]. In: Proceedings of the AACR Special Conference on Colorectal Cancer; 2022 Oct 1-4; Portland, OR. Philadelphia (PA): AACR; Cancer Res 2022;82(23 Suppl_1):Abstract nr B029.
Minorization-based Low-Complexity Design for IRS-Aided ISAC Systems (2023)

A low-complexity design is proposed for an integrated sensing and communication (ISAC) system aided by an intelligent reflecting surface (IRS). The radar precoder and IRS parameter are computed alternatingly to maximize the weighted sum signal-to-noise ratio (SNR) at the radar and communication receivers. The IRS design problem has an objective function of fourth order in the IRS parameter matrix, and is subject to highly non-convex unit modulus constraints. To address this challenging problem and obtain a low-complexity solution, we employ a minorization technique twice; the original fourth order objective is first surrogated with a quadratic one via minorization, and is then minorized again to a linear one. This leads to a closed form solution for the IRS parameter in each iteration, thus reducing the IRS design complexity. Numerical results are presented to show the effectiveness of the proposed method.
The Saccharomyces cerevisiae bud-neck proteins Kcc4 and Gin4 have distinct but partially-overlapping cellular functions (2003)

In the budding yeast S. cerevisiae, Swe1 delays the onset of mitosis by phosphorylation and inactivation of the cyclin-dependent kinase Cdc28, thereby relaying the morphogenetic signal to the cell cycle. Hsl1/Nik1, Kcc4 and Gin4 are structurally homologous protein kinases that localize to the bud neck and negatively regulate Swe1 by phosphorylation. We report here that Kcc4 and Gin4 have partially overlapping but essentially distinct cellular functions. Deletion of KCC4 had a similar effect to GIN4 deletion, causing moderate defects in bud formation at stationary phase; overexpression of Kcc4 inhibited cell growth. KCC4 showed functional interaction with GIN4 in cdc28 mutants, and both Kcc4 and Gin4 proteins physically interacted with Swe1 in vitro. However, unlike gin4delta cells, kcc4Delta cells were not elongated but multi-budded at stationary phase, and showed resistance to 0.04% SDS and 0.003% calcofluor white. In light of the observation that Kcc4 and Gin4 specifically associate with distinct septin proteins, we propose that the observed functional distinction between Kcc4 and Gin4 is due to differences in septin association partners.
Space time frequency coding for dual polarization MIMO in hybrid mobile satellite system (2013)

在一个单个频率网络(SFN ) 操作模式的混合活动卫星系统逐渐地正在变得吸引人。卫星部件(SC ) 和陆上的部件(TC ) 的联合答应服务(QoS ) 的更好的质量。多媒体广播了并且多点传送服务(MBMS ) 被期望在这种系统被占优势。几空间频率(SF ) 或时间(圣) 编码的空间被建议了由于反向的连接和全向的传播的缺乏提高系统性能。然而，他们主要与仅仅一 SC 和一 TC 考虑系统并且没能充分利用可得到的差异。这份报纸论述一个新奇方法认识到双极化多重输入由使用空间时间频率(STF ) 的多重产量(MIMO ) 传播代码。理论分析和模拟显示 STF 代码的应用程序能戏剧性地改进系统性能。更高的差异获得能由于 SC 和 TC 的合作传播被完成，当编码获得能被再使用在 SC 或 TC 之间的 STF 代码提高时。就算一些连接被失去，它能仍然适当地工作并且得益于 STF 代码。相对继电器能在编码获得导致降级直到 0.5 dB。
Event‐related potential and functional MRI measures of face‐selectivity are highly correlated: A simultaneous ERP‐fMRI investigation (2010)

Abstract A face‐selective neural signal is reliably found in humans with functional MRI and event‐related potential (ERP) measures, which provide complementary information about the spatial and temporal properties of the neural response. However, because most neuroimaging studies so far have studied ERP and fMRI face‐selective markers separately, the relationship between them is still unknown. Here we simultaneously recorded fMRI and ERP responses to faces and chairs to examine the correlations across subjects between the magnitudes of fMRI and ERP face‐selectivity measures. Findings show that the face‐selective responses in the temporal lobe (i.e., fusiform gyrus—FFA) and superior temporal sulcus (fSTS), but not the face‐selective response in the occipital cortex (OFA), were highly correlated with the face‐selective N170 component. In contrast, the OFA was correlated with earlier ERPs at about 110 ms after stimulus‐onset. Importantly, these correlations reveal a temporal dissociation between the face‐selective area in the occipital lobe and face‐selective areas in the temporal lobe. Despite the very different time‐scale of the fMRI and EEG signals, our data show that a correlation analysis across subjects may be informative with respect to the latency in which different brain regions process information. Hum Brain Mapp, 2010. © 2010 Wiley‐Liss, Inc.
Effects of an Occupational Therapy Program on Functional Outcomes in Older Stroke Patients (2006)

Our results show that patients with stroke who received occupational therapy had a greater level of independence in activities of daily living over a period of 8 weeks than patients who did not.
How to Manage Opioid-Related Constipation in Individuals With Chronic Nonmalignant Pain Syndromes (2020)

Brenner, Darren M. MD1; Barrett-Englert, Meghan MD, MS2; Cash, Brooks D. MD3 Author Information
Condenser Tube Examination Using Acoustic Pulse Reflectometry (2009)

Acoustic pulse reflectometry (APR) has been applied extensively to tubular systems in research laboratories for purposes of measuring input impedance, bore reconstruction, and fault detection. Industrial applications have been mentioned in the literature, though they have not been widely implemented. Academic APR systems are extremely bulky, often employing source tubes of 6 m in length, which limits their industrial use severely. Furthermore, leak detection methods described in the literature are based on indirect methods, by carrying out bore reconstruction and finding discrepancies between the expected and reconstructed bore. In this paper we describe an APR system designed specifically for detecting faults commonly found in industrial tube systems: leaks, increases in internal diameter caused by wall thinning, and constrictions. The system employs extremely short source tubes, in the order of 20 cm, making it extremely portable, but creating a large degree of overlap between forward and backward propagating waves in the system. A series of algorithmic innovations enable the system to perform the wave separation mathematically, and then identify the above faults automatically with a measurement time on the order of 10 s per tube. We present several case studies of condenser tube inspection, showing how different faults are identified and reported.
Evaluation of plasma melter technology for verification of high-sodium content low-level radioactive liquid wastes: Demonstration test No. 4 preliminary test report (1995)

This document provides a preliminary report of plasma arc vitrification testing by a vendor in support of the Hanford Tank Waste Remediation System Low-Level Waste (LLW) Vitrification Program. Phase I test conduct included 26 hours (24 hours steady state) of melting of simulated high-sodium low-level radioactive liquid waste. Average processing rate was 4.9 kg/min (peak rate 6.2 kg/min), producing 7330 kg glass product. Free-flowing glass pour point was 1250 C, and power input averaged 1530 kW(e), for a total energy consumption of 19,800 kJ/kg glass. Restart capability was demonstrated following a 40-min outage involving the scrubber liquor heat exchanger, and glass production was continued for another 2 hours. Some volatility losses were apparent, probably in the form of sodium borates. Roughly 275 samples were collected and forwarded for analysis. Sufficient process data were collected for heat/material balances. Recommendations for future work include lower boron contents and improved tuyere design/operation.
Nonmyeloablative Unrelated Donor Hematopoietic Cell Transplantation to Treat Patients with Poor-Risk, Relapsed, or Refractory Multiple Myeloma (2007)

The purpose of this study was to determine long-term outcome of unrelated donor nonmyeloablative hematopoietic cell transplantation (HCT) in patients with poor-risk multiple myeloma. A total of 24 patients were enrolled; 17 patients (71%) had chemotherapy-refractory disease, and 14 (58%) experienced disease relapse or progression after previous autologous transplantation. Thirteen patients underwent planned autologous transplantation followed 43-135 days later with unrelated transplantation, whereas 11 proceeded directly to unrelated transplantation. All 24 patients were treated with fludarabine (90 mg/m(2)) and 2 Gy of total body irradiation before HLA-matched unrelated peripheral blood stem cell transplantation. Postgrafting immunosuppression consisted of cyclosporine and mycophenolate mofetil. The median follow-up was 3 years after allografting. One patient experienced nonfatal graft rejection. The incidences of acute grades II and III and chronic graft-versus-host disease were 54%, 13%, and 75%, respectively. The 3-year nonrelapse mortality (NRM) was 21%. Complete responses were observed in 10 patients (42%); partial responses, in 4 (17%). At 3 years, overall survival (OS) and progression-free survival (PFS) rates were 61% and 33%, respectively. Patients receiving tandem autologous-unrelated transplantation had superior OS and PFS (77% and 51%) compared with patients proceeding directly to unrelated donor transplantation (44% and 11%) (PFS P value = .03). In summary, for patients with poor-risk, relapsed, or refractory multiple myeloma, cytoreductive autologous HCT followed by nonmyeloablative conditioning and unrelated HCT is an effective treatment approach, with low NRM, high complete remission rates, and prolonged disease-free survival.
Microporous polymeric materials (2004)

Microporous materials are solids that contain interconnected pores of molecular dimensions (i.e. <2 nm). Such materials possess large surface areas, typically 300-1500 m2 g−1, and are of great technological importance for adsorption and heterogeneous catalysis1. There are two main classes of microporous materials widely used in industry: crystalline zeolites (aluminosilicates) and activated carbons. In the past decade, there has been an intense effort to optimize the porosity of these materials for various applications2, 3. However, it is recognized that the design of entirely new microporous materials would open up exciting opportunities for fundamental research and industrial applications3.
Maximum-likelihood extremum seeking control of microalgae cultures (2021)

This paper proposes a model-free extremum seeking control (ESC) approach to optimize the productivity of continuous cultures of microalgae, considering the dilution rate and the light intensity as manipulated variables, and the biomass concentration as single measurement. The resulting two-input single-output optimization problem is first solved using a recursive least-squares strategy based on the representation of the process by a Hammerstein block-oriented model. In order to face the presence of noise on the regressor variables (input and output signals), the problem is then reformulated as a maximum-likelihood estimation problem, which is solved on a moving horizon. Simulation results demonstrate the method performance.
The status of stability theory for deterministic systems (1966)

This paper attempts to summarize and place in perspective some of the recent contributions to stability theory. The major emphasis is on work which relates closely to applications in control, circuit theory, and aerospace systems. The frequency domain stability criteria for nonlinear and time-varying feedback loops are discussed in some detail. A large number of references describing both theoretical developments and applications are included.
A Matched Filter For Communicating With Chaos (2011)

In conventional communication systems, a matched filter provides optimal receiver performance in the presence of noise. As such, matched filters are highly desirable, yet they are practical only when a relatively small number of known basis functions are used to represent information. For communications using chaotic waveforms, the unpredictable and nonrepeating nature of chaos suggests the basis functions are uncertain and ever changing, which would preclude the use of a simple matched filter. Consequently, it is widely accepted that the performance of chaos communications lags that of conventional, no chaotic systems. In this paper, we show this assumption is not necessarily true. We describe a simple, low‐dimensional chaotic oscillator that admits an exact analytic solution containing a single fixed basis function. The solution is written as the linear convolution of a symbol sequence and the basis function, similar to how conventional communications waveforms are usually represented. Despite the linear nature of the solution, waveform returns sampled at regular switching times are conjugate to a shift map, proving the oscillator is chaotic. A matched filter for the basis function is defined and used to extract symbolic information from the chaotic wave‐form. Its performance in additive white Gaussian noise is comparable to that of binary phase‐shift keying (BPSK). The oscillator and its matched filter have potential application in Hayes‐type chaos communications where a message signal is encoded in the symbolic dynamics via small perturbation control. The discovery of a practical matched filter for chaos finally provides a coherent receiver to complement this elegant encoding scheme.