gebhart/patrepeval huggingface dataset:
Synchronization of high‐order oscillators by observer design with application to hyperchaos‐based cryptography (1999)

The aim of this paper is to make a contribution in the context of both hyperchaos synchronization and cryptography. The approach illustrated herein, which exploits the concept of observer from system theory, is at first applied for synchronizing via a scalar signal two recent examples of high-order oscillators, characterized by several positive Lyapunov exponents. Successively, an example of hyperchaos-based cryptography is illustrated. The advantages of the proposed tool are discussed in detail. In particular, the utilization of both synchronization of complex dynamics and cryptography seems to make a contribution to the development of communication systems with higher security. Copyright © 1999 John Wiley & Sons, Ltd.
Circulating cell-free DNA as predictor of pathological complete response in locally advanced rectal cancer patients undergoing preoperative chemoradiotherapy (2022)

BackgroundThe watch and wait (W&W) strategy is proposed for patients with locally advanced rectal cancer (LARC) achieving clinical complete response (cCR) after neoadjuvant radiotherapy. cCR is only in partial concordance with pathological complete response (pCR) due to persisting viable tumour cells. The aim was to investigate circulating-free-deoxyribonucleic-acid (cfDNA) as a biomarker for prediction of pCR.Materials and methodsPatients treated with neoadjuvant radiotherapy for LARC, were included in a prospective biomarker study in Aarhus, Denmark from 2017 to 2020. Plasma cfDNA levels were analysed by a direct fluorescent assay (DFA). Surgical specimens were reviewed by pathologists to categorize response to cytotoxic therapy.ResultsIn total, 76 patients were included with plasma available at baseline (n = 70), mid therapy (n = 50), and end of therapy (n = 54). Higher cfDNA levels were observed in LARC patients compared with healthy subjects (p < 0.01). By ROC analysis (AUC: 0.87 (95% CI, 0.81–0.92)) the optimal cut-off was 0.71 ng/µL for differentiation between healthy subjects and LARC patients. Thirteen patients obtained pCR with a median cfDNA level of 0.57 ng/µL at end of therapy. Patients with cfDNA levels at end of therapy below the cut-off (p < 0.02) and ‘cfDNA responders’ with descending levels greater than the 75th percentile during therapy had a significantly higher chance of pCR (p < 0.01).ConclusionThis hypothesis generating study indicates that low cfDNA levels at end of treatment or ́cfDNA responderś might be associated with pCR. Quantification of cfDNA by the rapid and feasible DFA analysis could potentially facilitate personalized follow-up as a complementary tool to identify candidates for a W&W strategy.
Adsorption Behaviors and Mechanism of Single/Multi-Metals by Ion Exchange Resins (2019)

Adsorption of Fe(Ш), Co(II), Cu(II), Zn(II) and K(I) by strong acid resins, Dowex 50WX2 200-400 (H) and Amberlite IRP-69, was studied to investigate the adsorption behaviors and mechanism in single-metal and multi-metal systems. The results showed that 99.9% Fe(III) can be removed by Dowex 50WX2 200-400 (H) in 100 min ([Fe(Ш)] 40 mg/L, resin amount = 50 mg, pH = 3.0, 60℃). Mechanism studies revealed that Langmuir model and pseudo-second- order kinetic equation illustrate better fit for the adsorption of Fe(Ш). Furthermore, the investigations on multi-metal adsorption indicated that resins display a similar adsorption ratio for the same-valence metal ions (Co(II) = Cu(II) = Zn(II)), and a more selective adsorption for high-valence metal ions than low-valence metal ions (Fe(III) Co(II) K(I)). The above results can be used for the treatment of wastewater and the recovery of metals from the spent catalysts.
CO Fixation to Stable Acyclic and Cyclic Alkyl Amino Carbenes: Stable Amino Ketenes with a Small HOMO–LUMO Gap (2006)

Fix gebunden: Anders als cyclische Diaminocarbene reagieren stabile Alkylaminocarbene mit CO zu stabilen Ketenen (Schema oben). Im Unterschied zu den acyclischen Derivaten können cyclische Aminoketene der destabilisierenden n-π-Donorfunktion des freien N-Elektronenpaars nicht ausweichen, was zu einem Diradikalcharakter und ungewöhnlichen optischen (Schema unten und Photos von Kristallen) wie NMR-spektroskopischen Eigenschaften führt. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2001/2006/z600987_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
A Finite Element Analysis of Dynamically Loaded Journal Bearings in Mixed Lubrication (1998)

Modern high performance engines require bearings to operate under high temperature and heavy bad with complicated hading cycles. These severe conditions result in mainshaft and connecting rod bearings operating in an ever thin film lubrication regime. The effects of surface waviness, roughness and bearing housing deformation can no longer be neglected. To account for such effects a mixed elastohydrodynamic lubrication model for finite-long journal bearings has been developed. This model couples an average Reynolds equation for a particular longitudinal surface texture with an asperity-to-asperity contact model. The governing equations of the model were discretized by the finite element method. The resulting nonlinear equations were subsequently solved by a modified Newton-Raphson algorithm. Simulations have been performed for various waviness and roughness with both rigid and flexible bearing housings.
Protein engineering of domains in flavoprotein disulphide oxidoreductases: Contributions to folding and assembly (1996)

Conference Article| February 01 1996 Protein engineering of domains in flavoprotein disulphide oxidoreductases: Contributions to folding and assembly R. N. Perham; R. N. Perham * *To whom correspondence should be addressed. Search for other works by this author on: This Site PubMed Google Scholar B. Leistler; B. Leistler † Search for other works by this author on: This Site PubMed Google Scholar R. G. Solomon; R. G. Solomon 1Cambridge Centre for Molecular Recognition, Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge CB2 1QW, U.K. Search for other works by this author on: This Site PubMed Google Scholar P. Guptasarma P. Guptasarma 1Cambridge Centre for Molecular Recognition, Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge CB2 1QW, U.K. Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1996) 24 (1): 61–66. https://doi.org/10.1042/bst0240061 Article history Received: September 14 1995 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation R. N. Perham, B. Leistler, R. G. Solomon, P. Guptasarma; Protein engineering of domains in flavoprotein disulphide oxidoreductases: Contributions to folding and assembly. Biochem Soc Trans 1 February 1996; 24 (1): 61–66. doi: https://doi.org/10.1042/bst0240061 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1996 Biochemical Society1996 Article PDF first page preview Close Modal You do not currently have access to this content.
Ferromagnetic coupling and electron transfer in CoCu(ben)·3H2O[H4ben =NN′-bis(2-hydroxy-3-carboxybenzylidene)-1,2-diaminoethane] (1978)

The title heterobinuclear complex exhibits a very strong ferromagnetic coupling due to the orthogonality of the magnetic orbitals; it can also show the intramolecular electron transfer CoIICuII⇌ CoIIICuI.
A novel backward extrusion process through rotating die and open punch (2017)

In this study, a new method of backward extrusion through rotating die and open punch, named rotating backward extrusion (RBE), is proposed. In this new process, a torque is imposed on the die that drives billet rotating. The rotating billet was backward extruded with the use of the punch with end face groove. To investigate the capability of this process, the experiment and finite element (FE) analysis were carried out for AZ80 magnesium alloy used as experimental material. The effects of rotating speed on the effective strain and process load were analyzed. The effective strain of the final part and process load were compared for cup extrusion by both the conventional and the new process respectively. The results showed that the average effective strain through the processed sample was approximately higher in 3 times the value of the sample processed via the conventional backward extrusion. The reduction of process load is about 20% in maximum in comparison with the conventional backward extrusion process. This new process has proven to be promising for the hollow parts production because of lower process force and imposing higher effective strain. The potential for grain refinement and mechanical properties improvement are required to fully evaluate for the new process.
Viscosity of LiquidHe3-Bnear the Superfluid Transition (1978)

The normal-fluid viscosity of liquid $^{3}\mathrm{He}$-$B$ has been determined in the neighborhood of the superfluid transition using the torsional-oscillator technique of Andronikashvili. In the pressure range from 11.90 to 19.64 bars and for reduced temperatures $t\ensuremath{\equiv}\frac{T}{{T}_{c}}&gt;0.98$, the $B$-phase viscosity may be described by $\frac{\ensuremath{\eta}}{{\ensuremath{\eta}}_{c}}=1\ensuremath{-}[A{(1\ensuremath{-}t)}^{\frac{1}{2}}\ensuremath{-}B(1\ensuremath{-}t)]$, where ${\ensuremath{\eta}}_{c}$ is the value of the viscosity at the transition temperature. $A$ and $B$ have the values 6.3\ifmmode\pm\else\textpm\fi{}0.2 and 20.0\ifmmode\pm\else\textpm\fi{}1.0, respectively.
Defining Road and Rail Vehicles with a Low Environmental Footprint (2016)

Determining the environmental footprint of heavy vehicles and limiting this footprint is a complex task that requires the involvement of all stakeholders. The ongoing Ecovehicle project that is summarized in this paper demonstrates that the footprint of heavy vehicles can be quantified. It was shown that in each vehicle category there are those with a high total footprint indicating a large difference between vehicles in every category and a high potential for improvement. A recent study in Switzerland has calculated the external costs of the four modes of transport, to be over CHF 9’400 million for 2010. It was shown that most of these costs are not recovered. Considering the external cost of freight transport, the report shows that the freight traffic cost 7.1 Rp/tkm of which 4.4 Rp/tkm was internalized through the heavy vehicle fee (LSVA), implying in turn that 2.7 Rp/tkm was not recovered by the fee. The external cost of rail on the other hand was 2.8 Rp/tkm, air freight 7.6 Rp/tkm whereas the cost of ship transport on the Rhein was 0.5 Rp/tkm. Promoting ecofriendly vehicles however requires the introduction of incentives, and bonus-malus systems Europe wide. Data quality is of particular importance when comparing the environmental effects in different European countries. The data reported here, the external costs as well as the incentives discussed are from Switzerland however, the general conclusions can be extended to all modes of transport and other countries as the results are universal.
Measuring and modeling optical diffraction from subwavelength features (2001)

We describe a technique for studying scattering from subwavelength features. A simple scatterometer was developed to measure the scattering from the single-submicrometer, subwavelength features generated with a focused ion beam system. A model that can describe diffraction from subwavelength features with arbitrary profiles is also presented and shown to agree quite well with the experimental measurements. The model is used to demonstrate ways in which the aspect ratios of subwavelength ridges and trenches can be obtained from scattering data and how ridges can be distinguished from trenches over a wide range of aspect ratios. We show that some earlier results of studies on distinguishing pits from particles do not extend to low-aspect-ratio features.
Behaviour of environmentally aged PAH and PCB residues in soil. (2005)

Laboratory studies are useful for understanding the behavior of persistent organic pollutants (POPs) in soil, although such investigations do not always relate directly to field conditions. Outdoor lysimeter studies may be used to overcome this problem. This work aimed to investigate the behavior of two polycyclic aromatic hydrocarbons (PAHs) (fluoranthene and benzo[a]pyrene) and two polychlorinated biphenyls (PCBs; congeners 28 and 52) in soil, using lysimeters established in 1990 at the Agrosphere Institute (Forschungszentrum Julich GmbH, Germany). The two PAHs were in one lysimeter, and the PCBs were in a second lysimeter. A further aim of the study was to determine soil half-lives for each of the contaminants. The overall decline in PAH concentrations was considerably greater than for the PCBs over the 152 month study. The PCBs exhibited greater chemical extractability than the PAHs and were demonstrated to have migrated through the soil column to a greater extent than the PAHs. Loss of PCBs from surface soil was not considered to have been congener specific for the two PCB congeners in this study. The two PAHs varied in their extents of total loss and movement through the soil column. Soil half-lives were determined as 10.9 y for [12C]PCB 28, 11.2 yr for [12C]PCB 52, 2.7 yr for benzo[a]pyrene, and 32 d (phase 1) to 38 yr (phase 2) for fluoranthene. These are shown to disagree with some previous estimates of POP half-lives in soil, suggesting that previous studies underestimated persistence by 10-fold or more.
Postoperative Analgesia for Outpatient Arthroscopic Knee Surgery with Intraarticular Clonidine and/or Morphine (2000)

Both clonidine, an alpha(2) agonist, and morphine, an opioid agonist, provide enhanced patient analgesia after arthroscopic knee surgery when administered via the intraarticular (IA) route. Clonidine potentiates morphine analgesia in the animal model. We designed this study to determine whether clonidine or morphine results in better analgesia and whether their combination would provide superior analgesia to either drug alone. We evaluated 60 patients undergoing arthroscopic knee meniscus repair under local anesthesia with sedation. After surgery, patients were randomized into four IA groups: Group B received 30 mL 0.25% bupivacaine; Group BC received 30 mL 0.25% bupivacaine and clonidine 1 microg/kg; Group BM received 30 mL 0.25% bupivacaine and morphine 3 mg; and Group BCM received 30 mL 0.25% bupivacaine, clonidine 1 microg/kg, and morphine 3 mg. This study revealed a significant benefit from the individual IA administration of both clonidine and morphine. The combination of these drugs resulted in decreased postoperative pain and analgesic use, as well as an increased analgesic duration compared with either drug alone. We conclude that IA clonidine and morphine improved comfort compared with either drug alone in patients undergoing knee arthroscopy.
On eight new southern millipeds (1951)

The new millipeds described in the present paper were detected in the course of a study of a collection made by Hugh Hanson, now of the Arizona State College at Tempe, chiefly in June and July of 1947. With the exception of the type of Pseudotremia hansoni, which was taken at Pineville, Ky, the specimens were all taken near Gatlinburg, Tenn., in the Smoky Mts. I wish here to express my thanks to Mr. Hanson for the privilege of examining his interesting collection and for his patience
Smart Card Operating Systems: Past, Present and Future (2003)

Over the last twenty years, the software in smart cards has radically changed. This has happened for several reasons, smart card software was initially rigid and monolithic and has now become more flexible with a clear separation between ``operating system level&amp;apos;&amp;apos; and ``application level&amp;apos;&amp;apos; parts. What is more, application-level resources are now much more accessible (nearly to end user level). Nevertheless, smart cards have evolved separately from an ever more distributed ``outside world&amp;apos;&amp;apos;. This paper presents two contributions to next-generation smart card operating systems. The first, called CAMILLE, relies on the exo-kernel approach to obtain extensibility, without compromising security, raising making operating systems accessible to application designers. The second, called AWARE, reveals the mismatch between the smart card execution model and the role it is expected to play in distributed systems. We propose solutions that allow for multi-tasking and reactivity. Beyond these projects, there are a number of obstacles that need to be overcome before we can reach what might be the ultimate step in smart card operating system design. In conclusion, this paper presents current work around two related challenges, namely resource control and real-time operation.
Present issues on pharmacotherapy in older people (2018)

高齢者で薬物療法を安全かつ有効に実施することは非常に困難である．実際に，薬物動態の加齢変化やポリファーマシー（polypharmacy）を背景として，薬物有害事象（adverse drug events：広義の副作用．薬物アレルギー等確率的有害事象のほかに，薬効が強く出過ぎることによって起きる有害事象等薬物使用に関連した全ての有害事象）のリスクは高齢者ほど高く，残薬や処方の適正化という問題もある．特にポリファーマシー対策は喫緊の課題であり，「高齢者の安全な薬物療法ガイドライン2015」（日本老年医学会）をその対策に用いることができる．しかし，その内容には，まだ信頼性の高いエビデンスがない場合も多く，適用範囲と薬物の種類は定期的にupdateしていく必要がある．もう1つの課題は，高齢者の適切な薬物療法という考え方と上記ツールを普及・啓発することである．医療提供側はもとより，医療を受ける高齢者とその家族の理解がなければ適切な医療を提供し得ない．自治体を含めて地域包括ケアシステムに関わる全ての関係者が協力して啓発に努めていくべきである．
Fairness considerations in full-duplex MIMO interference channels (2015)

In this paper, we address the proportional fair (PF) issue of a K link full-duplex (FD) multiple-input multiple-output (MIMO) interference channel, where each link consists of two FD nodes exchanging information simultaneously. The nodes in each pair suffer from self-interference due to operating in FD mode, and inter-user interference from the nodes in other links due to simultaneous transmission from each link. The PF issue is important for networks with asymmetric topology and/or asymmetric traffic demands. We demonstrate that the proposed algorithm provides a good trade-off between sum achievable rate and rate distribution for asymmetric links, and moreover we show that the sum-rate achieved by FD mode is higher than the sum-rate achieved by baseline half-duplex (HD) schemes.
A Soft Interference Cancellation Inspired Neural Network for SC-FDE (2022)

Model-based estimation methods have been employed for the task of equalization since the beginning of digital communications. Due to the incredible success of data-driven machine learning approaches for many applications in different research disciplines, the replacement of model-based equalization methods by neural networks has been investigated recently. Incorporating model knowledge into a neural network is a possible approach for complexity reduction and performance enhancement, which is, however, very challenging. In this paper, we propose a novel neural network architecture for single carrier systems with frequency domain equalization inspired by a model-based soft interference cancellation scheme. We evaluate its bit error ratio performance in indoor frequency selective-environments and show that the proposed approach outperforms both model-based and data-driven state-of-the-art methods.
Empowering Device-to-Device Networks with Cross-Link Interference Management (2016)

Device-to-device (D2D) communications is an emerging service model that is currently under standardization by 3GPP. While D2D offloading has a great potential to relieve increasingly congested cellular networks, its benefits, however, come at a cost, namely interference. Most of the prevailing D2D designs conservatively avoid interference via either spectrum resource allocation or power control. These designs, however, do not exploit spatial degrees of freedom (DoF), which are inherently supported by multi-antenna devices. In this work, we present <inline-formula> <tex-math notation="LaTeX">$\sf {MD2D}$</tex-math></inline-formula> , a multiuser D2D system that embraces concurrent D2D transmissions, while leveraging MIMO techniques to actively eliminate interference across D2D pairs. <inline-formula><tex-math notation="LaTeX"> $\sf{MD2D}$</tex-math></inline-formula> has a systematic methodology that checks whether the antenna combination in a D2D network is capable of eliminating cross-pair interference and, thereby, ensuring interference-free concurrent transmissions. If the interference can be eliminated, then <inline-formula><tex-math notation="LaTeX">$\sf{MD2D}$</tex-math></inline-formula> applies a <i>bucket-based DoF assignment algorithm</i> to determine an effective antenna usage configuration that handles the interference. We evaluate our design via testbed experiments and large-scale simulations. The results show that, as compared to the traditional interference avoidance scheme, <inline-formula><tex-math notation="LaTeX">$\sf{MD2D}$</tex-math> </inline-formula> improves the throughput by 87.39 and 218.84 percent in a three-pair testbed and in large-scale simulations, respectively.
Investigation and current management of recurrent IVF treatment failure in the UK (2005)

The results of this survey suggest that there is considerable variation in the approach to investigation and management of recurrent IVF treatment failure in the UK, although in some areas (e.g. the definition) there was broad concordance. Not all of these approaches are evidence based.
The Histone Deacetylase Inhibitor Trichostatin A Promotes Totipotency in Cultured Pollen (2016)

The haploid multicellular male gametophyte of plants, the pollen grain, is a terminally differentiated structure whose function ends at fertilization. Unlike pollen grains, the immature gametophyte retains its capacity for totipotent growth when cultured in vitro. Haploid embryo production from cultured immature male gametophytes is a widely used plant breeding and propagation technique that was described nearly 50 years ago, but one that is poorly understood at the mechanistic level. Using a chemical approach, we show that the switch to haploid embryogenesis is controlled by the activity of histone deacetylases (HDACs). Blocking HDAC activity with trichostatin A (TSA) in cultured immature male gametophytes of Brassica napus leads to a large increase in the proportion of cells that switch from pollen to embryogenic growth. Embryogenic growth is enhanced by, but not dependent on, the high temperature stress that is normally used to induce haploid embryogenesis in B. napus. The immature male gametophyte of Arabidopsis thaliana, which is recalcitrant for haploid embryo development in culture, also forms embryogenic cell clusters after TSA treatment. TSA treatment of immature male gametophytes for as little as eight hours was accompanied by hyperacetylation of histones H3 and H4, and by the upregulation of genes involved in cell-cycle progression, the auxin pathway and cell wall catabolism pathways. We propose that the totipotency of the immature male gametophyte in planta is kept in check by an HDAC-dependent mechanism, and that high temperature or other stresses used to induce haploid embryo development in culture impinge on this HDAC-dependent pathway.