gebhart/patrepeval huggingface dataset:
Heteronuclear Hexaplatinum Cluster Complexes:  Structure as a Function of Electron Count (1998)

The 84-electron hexaplatinum cluster complex [Pt(6)(&mgr;-CO)(6)(&mgr;-dppm)(3)], 1, dppm = Ph(2)PCH(2)PPh(2), reacts in a 1:2 molar ratio with either 0-electron metalloligands LM(+) (L = Ph(3)P, M = Cu, Ag, Au; L = iPr(3)P, M = Au) or InX(3) (X = Cl, Br) or 2-electron metalloligands Tl(+) and Hg to give the corresponding 84-electron clusters [Pt(6)(&mgr;(3)-ML)(2)(&mgr;-CO)(6)(&mgr;-dppm)(3)](2+) or [Pt(6)(&mgr;(3)-InX(3))(2)(&mgr;-CO)(6)(&mgr;-dppm)(3)] or 88-electron clusters [Pt(6)(&mgr;(3)-Tl)(2)(&mgr;-CO)(6)(&mgr;-dppm)(3)](2+) and [Pt(6)(&mgr;(3)-Hg)(2)(&mgr;-CO)(6)(&mgr;-dppm)(3)], respectively. The mercury cluster is oxidized by CH(2)I(2) to give the known 86-electron cluster [Pt(6)(&mgr;(3)-HgI)(2)(&mgr;-CO)(6)(&mgr;-dppm)(3)]. Reaction of 1 with [Ir(CO)(4)](-) occurs in a 1:1 ratio only to give the 98-electron anionic cluster [Pt(6){&mgr;(3)-Ir(CO)(2)}(&mgr;-CO)(6)(&mgr;-dppm)(3)](-), which reacts with [Ph(3)PAu](+) to give [Pt(6){&mgr;(3)-Ir(CO)(2)}(&mgr;(3)-AuPPh(3))(&mgr;-CO)(6)(&mgr;-dppm)(3)]. The new cluster complexes are characterized by NMR and IR spectroscopies, and [Pt(6)(&mgr;(3)-AuPiPr(3))(2)(&mgr;-CO)(6)(&mgr;-dppm)(3)](2+) is also characterizedby an X-ray structure determination.
Dynamic behavior of SRAM data retention and a novel transient voltage collapse technique for 0.6V 32nm LP SRAM (2011)

A novel transient voltage collapse (TVC) technique is presented to enable low-voltage operation in SRAM. By dynamically switching off the PMOS during write operations with a collapsed supply voltage below the data retention voltage, a minimum operating voltage (V <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">ccmin</inf> ) of 0.6V is demonstrated in a 32nm 12-Mb low-power (LP) SRAM. Data retention failure of unselected cells is mitigated by controlling the duration of voltage collapse. Circuit-process co-optimization is critical to ensure robust circuit design margin of TVC technique.
Liver fat imaging—a clinical overview of ultrasound, CT, and MR imaging (2018)

Hepatic steatosis is a frequently encountered imaging finding that may indicate chronic liver disease, the most common of which is non-alcoholic fatty liver disease. Non-alcoholic fatty liver disease is implicated in the development of systemic diseases and its progressive phenotype, non-alcoholic steatohepatitis, leads to increased liver-specific morbidity and mortality. With the rising obesity epidemic and advent of novel therapeutics aimed at altering metabolism, there is a growing need to quantify and monitor liver steatosis. Imaging methods for assessing steatosis range from simple and qualitative to complex and highly accurate metrics. Ultrasound may be appropriate in some clinical instances as a screening modality to identify the presence of abnormal liver morphology. However, it lacks sufficient specificity and sensitivity to constitute a diagnostic modality for instigating and monitoring therapy. Newer ultrasound techniques such as quantitative ultrasound show promise in turning qualitative assessment of steatosis on conventional ultrasound into quantitative measurements. Conventional unenhanced CT is capable of detecting and quantifying moderate to severe steatosis but is inaccurate at diagnosing mild steatosis and involves the use of radiation. Newer CT techniques, like dual energy CT, show potential in expanding the role of CT in quantifying steatosis. MRI proton-density fat fraction is currently the most accurate and precise imaging biomarker to quantify liver steatosis. As such, proton-density fat fraction is the most appropriate noninvasive end point for steatosis reduction in clinical trials and therapy response assessment.
IMPACT OF ACTIVITY ON OUTCOME AFTER TOTAL HIP ARTHROPLASTY IN YOUNG PATIENTS (2000)

s of Scientific Papers and Posters Presented at the Annual Meeting of the Association of Academic Physiatrists
Charge Passing off-Axis through a Cylindrical Resonator with Beam Pipes (1985)

A charge is considered which passes off-axis through a cylindrical resonator with two semi-infinite beam pipes. In the pipe region the fields are represented by the source fields plus a continuous spectrum of waveguide modes and in the resonator region by an infinite, discrete set of resonator modes. Matching the fields at the common interface yields a set of linear equations for the expansion coefficients. The involved integrals are solved with the residuum calculus, where the poles are located so that only waves travelling away from the resonator region are taken into account. By truncating the system, numerical results were derived for the longitudinal and transverse impedance which, contrary to periodic systems, also have real parts due to radiation into the pipes.
Determination of the secondary structure of proteins by laser Raman spectroscopy (1976)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDetermination of the secondary structure of proteins by laser Raman spectroscopyJ. L. Lippert, D. Tyminski, and P. J. DesmeulesCite this: J. Am. Chem. Soc. 1976, 98, 22, 7075–7080Publication Date (Print):October 1, 1976Publication History Published online1 May 2002Published inissue 1 October 1976https://pubs.acs.org/doi/10.1021/ja00438a057https://doi.org/10.1021/ja00438a057research-articleACS PublicationsRequest reuse permissionsArticle Views2307Altmetric-Citations214LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A simple gene set-based method accurately predicts the synergy of drug pairs (2016)

Here we proposed a novel and simple method to predict and investigate drug synergy, and validated its efficacy to accurately predict synergistic drug combinations and to comprehensively explore their underlying mechanisms. The method is widely applicable to expression profiles of other drug treatments and is expected to accelerate the realization of precision cancer treatment.
ECMO in COVID-19—prolonged therapy needed? A retrospective analysis of outcome and prognostic factors (2021)

VV ECMO support for COVID-19-induced ARDS is justified if initiated early and at an experienced ECMO center. Prolonged ECMO therapy might be required in those patients. Although no relevant predictive factors for the duration of ECMO support were found, the decision to stop therapy should not be made dependent of the length of ECMO treatment.
Channel occupancy-based user association in IEEE 802.11 wireless LANs (2009)

It is usually possible to associate with more than one Access Point (AP) in IEEE 802.11 Wireless LANs. AP selection is a crucial issue because the performance achieved by a user heavily depends on the AP selected. A received signal strength (RSS)-based association mechanism is specified by the IEEE 802.11 standard. However, this does not consider the channel conditions and AP load, which leads to a low throughput and a low user transmission rate. An alternative to using the RSS is to exploit the airtime metric, which provides users with information on how busy the channel is, but the results of our simulations show that the airtime metric cannot indicate the exact status of the channel. In this paper, we present a new association framework using channel occupancy in order to provide users with exact channel status information of APs. Via the proposed scheme, users can compare the achievable throughput provided by each AP and select the best AP. We validate our proposed association method via simulation results, which show that the throughput improvement of the method is worthy of notice.
Enzyme Assay for Identification of Pectin and Pectin Derivatives, Based on Recombinant Pectate Lyase (2001)

A simple method was developed for fast identification of pectin, based on a recombinant endopectate lyase cloned from Aspergillus niger. When pectin was demethylated and treated with pectate lyase, beta-elimination occurred, resulting in a double bond between C-4 and C-5 in the galacturonic acid residue of the released nonreducing end. The formation of double bonds produced an increase in light absorption, which was detected at 235 nm. The assay was tested on pectin of different origins (apple, orange, sugar beet, sunflower, celery, lemon), pectin derivatives (amidated pectin), and speciality types such as low molecular weight and low %DE (degree of esterification, percentage of galacturonic acid groups esterified with methanol) pectin. The highest response was given by pectate (pectin with %DE< 5) and the lowest by pectin extracted from sugar beet. No other gums (carboxymethylcellulose, carrageenan, locust bean gum, tragacanth, gellan, tamarind, xanthan, amylogum, sodium alginate, or agar) gave any response. Members of IPPA (International Pectin Producers Association) have evaluated the validity of the assay in a ring test. All members of the Association were able to identify pectin from other gums in a blind test. The method can replace more laborious and ambiguous identification tests which exist today.
Growth factor-induced gene expression: the ups and downs of c-fos regulation. (1990)

Many growth factor-inducible immediate-early genes, including c-fos, encode transcription factors that are believed to propagate the mitogenic signal by activating a program of gene expression critical for cell proliferation. This review summarizes work aimed at elucidating the molecular mechanisms by which a growth factor-induced signal effects a change in gene expression. In the case of c-fos, both the activation and repression of transcription are mediated by the serum response element, a dyad symmetrical sequence found upstream of the c-fos gene. This element binds a complex of proteins, a component(s) of which may be the target of the growth factor-induced signal. Recent progress made towards understanding the roles of these factors in the regulation of c-fos transcription will be described.
Online performance evaluation of motor imagery BCI with augmented-reality virtual hand feedback (2010)

The online performance of a motor imagery-based Brain-Computer Interface (MI-BCI) influences its effectiveness and usability in real-world clinical applications such as the restoration of motor control. The online performance depends on factors such as the different feedback techniques and motivation of the subject. This paper investigates the online performance of the MI-BCI with an augmented-reality (AR) 3D virtual hand feedback. The subject experiences the interaction with 3D virtual hands, which have been superimposed onto his real hands and displayed on the computer monitor from a first person point-of-view. While performing motor imagery, he receives continuous visual feedback from the MI-BCI in the form of different degrees of reaching and grasping actions of the 3D virtual hands with other virtual objects. The AR feedback is compared with the conventional horizontal bar feedback on 8 subjects, of whom 7 are BCI-naïve. The subjects found the AR feedback to be more engaging and motivating. Despite the higher mental workload involved in the AR feedback, their online MI-BCI performance compared to the conventional horizontal bar feedback was not affected. The results provide motivation to further develop and refine the AR feedback protocol for MI-BCI.
Validation of the 30 Second Asthma Test™ as a Measure of Asthma Control (2007)

The results support the use of The 30 Second Asthma Test as a brief screening tool for asthma control.
Electrospray Ionization/Mass Spectrometric Analyses of Human Promonocytic U937 Cell Glycerolipids and Evidence That Differentiation Is Associated with Membrane Lipid Composition Changes That Facilitate Phospholipase A2 Activation (2000)

Upon differentiation, U937 promonocytic cells gain the ability to release a large fraction of arachidonate esterified in phospholipids when stimulated, but the mechanism is unclear. U937 cells express group IV phospholipase A(2) (cPLA(2)), but neither its level nor its phosphorylation state increases upon differentiation. A group VI PLA(2) (iPLA(2)) that is sensitive to a bromoenol lactone inhibitor catalyzes arachidonate hydrolysis from phospholipids in some cells and facilitates arachidonate incorporation into glycerophosphocholine (GPC) lipids in others, but it is not known whether U937 cells express iPLA(2). We confirm that ionophore A23187 induces substantial [(3)H]arachidonate release from differentiated but not control U937 cells, and electrospray ionization mass spectrometric (ESI/MS) analyses indicate that differentiated cells contain a higher proportion of arachidonate-containing GPC species than control cells. U937 cells express iPLA(2) mRNA and activity, but iPLA(2) inhibition impairs neither [(3)H]arachidonate incorporation into nor release from U937 cells. Experiments with phosphatidate phosphohydrolase (PAPH) and phospholipase D (PLD) inhibitors coupled with ESI/MS analyses of PLD-PAPH products indicate that differentiated cells gain the ability to produce diacylglycerol (DAG) via PLD-PAPH. DAG promotes arachidonate release by a mechanism that does not require DAG hydrolysis, is largely independent of protein kinase C, and requires cPLA(2) activity. This may reflect DAG effects on cPLA(2) substrate state.
The role of the LGN on the spatial frequency dependence of surround suppression in V1: Investigations using a computational model (2005)

Using a large scale model of macaque V1, we have shown (Wielaard & Sajda 2003, 2005) how only local short-range (<0.5 mm) connections within V1 can mediate surround suppression and account for a large fraction of the magnitude of suppression seen experimentally. In our model surround suppression arises from one of three mechanisms: (A) an increase in cortical inhibition, (B) a decrease in cortical excitation, or (C) both of these simultaneously. It is known that LGN neurons exhibit both classical and extraclassical surround suppression, with classical surround suppression observed at lower spatial frequencies. This leaves open the question of whether the unexplained fraction of suppression seen in our model could be inherited from the LGN or instead requires considering long-range lateral connections and/or extrastriate feedback. Using our model, we consider the effect of classical LGN surround suppression on suppression in V1 cortical neurons, in particular by measuring the distribution of the suppression index at spatial frequencies that are a quarter of those typically used to optimally drive cortical neurons. We find that at these lower spatial frequencies, nearly all of the classical surround suppression of LGN cells is transferred to V1 cells, either via direct LGN input into the cell and/or suppression of recurrent cortico-cortical excitation. We also see that at these low spatial frequencies, the prevalence of the cortical mechanisms for surround suppression is shifted in favor of mechanisms B and C, which rely on the reduction of excitation. This shift occurs at the expense of mechanism A, which relies on direct inhibition. Our model thus predicts 1) a substantial increase in V1 surround suppression is possible by sufficiently lowering the stimulus spatial frequency and 2) that ultimately the magnitude of surround suppression seen in V1 neurons is explainable by considering only the short-range cortical connections and the LGN input.
Seismic Behavior of Corroded RC Bridges: Review and Research Gaps (2016)

Chloride-induced corrosion and its effect on structural and seismic performance of reinforced concrete (RC) structures have been the topic of several research projects in past decades. This literature review summarizes the state of the art by presenting a brief description of chloride-induced corrosion, its main characteristics and influencing factors, a summary of experimental published data, and existing corrosion-induced deterioration models together with numerical and experimental methods used to evaluate corroded RC bridge pier. This literature review highlights the need for reliable deterioration models for RC structures and appropriate analysis methods are needed for design of new structures or assessment of existing civil engineering structures especially in seismic areas.
Tracing Patterns of Chloroplast Evolution in Euglenoids: Contributions from Colacium vesiculosum and Strombomonas acuminata (Euglenophyta) (2013)

The chloroplast genomes of two photosynthetic euglenoids, Colacium vesiculosum Ehrenberg (128,889 bp), and Strombomonas acuminata (Schmarda) Deflandre (144,167 bp) have been sequenced. These chloroplast genomes in combination with those of Euglena gracilis, Eutreptia viridis, and Eutreptiella gymnastica provide a snapshot of euglenoid chloroplast evolution allowing comparisons of gene content, arrangement, and expansion. The gene content of the five chloroplast genomes is very similar varying only in the presence or absence of, rrn5, roaA, psaI, psaM, rpoA, and two tRNAs. Large gene rearrangements have occurred within the C. vesiculosum and S. acuminata chloroplast genomes. Most of these rearrangements represent repositioning of entire operons rather than single genes. When compared with previously sequenced genomes, C. vesiculosum and S. acuminata chloroplast genomes more closely resemble the E. gracilis chloroplast genome in size of the genome, number of introns, and gene order than they do those of the Eutreptiales. Overall, the chloroplast genomes of these five species show an evolutionary trend toward increased intron number, a decrease in gene density, and substantial rearrangement of gene clusters.
Statistical Methods to Assessing Responses Over Time in Bioassays with Mixtures (1999)

Journal Article Statistical Methods to Assessing Responses Over Time in Bioassays with Mixtures Get access Haiganoush K. Preisler, Haiganoush K. Preisler 1 1USDA Forest Service, PSW Research Station, 800 Buchanan St. West Annex, Albany, CA 94710 Search for other works by this author on: Oxford Academic PubMed Google Scholar Jacqueline L. Robertson, Jacqueline L. Robertson 2 2Optimum, 1007 B Street., Petaluma, CA 94952 Search for other works by this author on: Oxford Academic PubMed Google Scholar Kelli Hoover, Kelli Hoover 3 3Department of Entomology, 501 ASI Bldg. Pennsylvania State University, University Park, PA 16802 Search for other works by this author on: Oxford Academic PubMed Google Scholar Bill F. McCutchen Bill F. McCutchen 4 4DuPont Ag Products, Stine-haskell Research Center, P.O. Box 30, Elkton Rd., Newark, DE 19714 Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Economic Entomology, Volume 92, Issue 3, 1 June 1999, Pages 598–603, https://doi.org/10.1093/jee/92.3.598 Published: 01 June 1999
Chip-based super-resolution structured illumination microscopy (Conference Presentation) (2020)

Fluorescence microscopy is an indispensable tool in biology and medicine, fuelling many breakthrough discoveries in a wide set of sub-domains. Yet, the resolution is intrinsically restricted by the diffraction limit. The last two decades have witnessed the emergence of several super-resolution fluorescence microscopy techniques that are breaking this limit (cfr. Nobel Prize in Chemistry 2014). Structured illumination microscopy (SIM) is one of such techniques that has gained much popularity and is available in commercial systems. In SIM, a biological sample is illuminated by a spatially structured light field — a sinusoidal interference pattern — which causes normally inaccessible high-resolution information to be encoded into the observed image due to the Moiré effect. Typically, the illumination patterns are generated by a grating or SLM and focused onto the sample through an objective lens to excite the fluorophores. Next, the fluorescence is transmitted to the imager through the same lens. Multiple images are taken under certain illumination patterns and used to reconstruct a single super-resolved image. However, making use of free space optics, state-of-the-art SIM systems require multiple bulky and precision optical components that give these systems the drawbacks of high cost and cumbersome size. In this talk, a structured illumination microscopy system based on a photonic integrated circuit (PIC) is presented. The unique properties of photonic integrated circuits allow us to create truly innovative microscopy systems that have the potential to go well beyond the current state-of-the-art: higher resolution due to the use of high refractive index materials, easier alignment with on-chip illumination light path, large field of view, a compact form factor resulting from on-chip integration, and lower cost due to compatibility with CMOS chip fabrication.
Vibrational Relaxation in Liquid Dibromomethane (1966)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Joseph L. Hunter, Henry D. Dardy; Vibrational Relaxation in Liquid Dibromomethane. J. Chem. Phys. 1 May 1966; 44 (9): 3637–3638. https://doi.org/10.1063/1.1727278 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioThe Journal of Chemical Physics Search Advanced Search |Citation Search
AES as Error Correction: Cryptosystems for Reliable Communication (2022)

In this paper, we show that the Advanced Encryption Standard (AES) cryptosystem can be used as an error-correcting code to obtain reliability over noisy communication and data systems. Moreover, we characterize a family of computational cryptosystems that can potentially be used as well performing error correcting codes. In particular, we show that simple padding followed by a cryptosystem with uniform or pseudo-uniform outputs can approach the error-correcting performance of random codes. We empirically contrast the performance of the proposed approach using AES as error correction with that of Random Linear Codes and CA-Polar codes and show that in practical scenarios, they achieve almost the same performance. Finally, we present a modified counter mode of operation, named input plaintext counter mode, in order to utilize AES for multiple blocks while retaining its error correcting capabilities.
Actinomycin and DNA transcription. (1985)

Recent advances in understanding how actinomycin binds to DNA have suggested its mechanism of action. Actinomycin binds to a premelted DNA conformation present within the transcriptional complex. This immobilizes the complex, interfering with the elongation of growing RNA chains. The model has a number of implications for understanding RNA synthesis.