gebhart/patrepeval huggingface dataset:
Automatic swing control in relaxation oscillators (1998)

An automatic swing control (ASC) feedback is presented for relaxation voltage-controlled oscillators (VCO's). The ASC feedback maintains the oscillation swing at a constant level by dynamically adjusting the threshold voltage of the oscillator. The feedback mechanism provides a very wide linear frequency range and pushes saturation in the frequency characteristic of the oscillator to higher frequencies. As a result, operation close to the maximum achievable frequency, set by the inherent delay of the oscillation loop, becomes practically possible. Also, the sensitivity of the VCO frequency characteristic to process and temperature variations is reduced. These features make the ASC oscillator particularly suitable for autorate operation in serial-digital video applications. A detailed description of the design and experimental results of a trimmable VCO are given in this paper. It is shown that the frequency range is increased from 20-500 to 20-800 MHz when the ASC feedback is applied. In addition, statistical data from more than 1000 samples from several batches before and after trimming are provided. The results confirm the manufacturability of the ASC feedback approach. The implementations were done in a semicustom 14-GHz bipolar process.
Non-apoptotic signaling through Fas activates Akt and promotes T cell differentiation through Caspase-8 (2017)

Abstract The TNF receptor Fas (CD95, TNFRSF6) is known for inducing apoptosis in primary cells via binding with Fas ligand (FasL) and activation of caspase-8 through the adapter protein FADD. In addition, recent research showed that the apoptotic signaling requires palmitoylation of Fas near its transmembrane region to localize on the lipid rafts. Fas palmitoylation-defective mutant is unable to induce apoptosis in primary cells but continues to enhance T cell differentiation into effector memory cells (CD44hiCD62Llo), indicating that Fas can also trigger non-apoptotic signaling in primary T cells. Fas non-apoptotic signaling has unexpected roles in modulating T cell tumor immunotherapy and autoimmunity (Klebanoff et al. 2016; Cruz et al. 2016). We have investigated the signaling pathways underlying non-apoptotic Fas signaling in T cells. Co-stimulation with oligomerized Fas Ligand activates Akt and ribosomal S6 protein phosphorylation, and Fas induced T cell differentiation is blocked by Akt or mTOR inhibitors. Further studies showed that T cells from RIP3−/− and Caspase-8−/− double deficient mice, but not mice deficient in RIP3, were refractory to Fas-induced differentiation, indicating that Caspase 8 is essential for Fas non-apoptotic signaling. Similar results were obtained with FADD. Our findings suggest that in addition to apoptotic functions, Fas also promotes non-apoptotic signaling via Caspase-8 and induces T cell differentiation by activating the Akt pathway. These results reveal a common role for Caspase-8 in non-apoptotic and apoptotic functions of Fas, with potentially different caspase-8 substrates mediating these diverse functions of a single receptor.
The Effect of Proton Pump Inhibitors on Bone Formation in a Rat Spinal Arthrodesis Model (2019)

N/A.
A second-order magnetocaloric model substance for standardization purposes. (2015)

Magneto Caloric Materials (MCM’s) are the working fluids (refrigerants) of magnetic heating/heat pumping, cooling/refrigeration and energy conversion. Physically they exhibit the magnetocaloric effect. The technologies applying these materials are coming increasingly into the focus of interest, and first approaches of magnetic refrigerators, e.g. wine coolers, etc., to refrigeration markets have been recently announced. The physical modeling of devices operating with the Magneto Caloric Effect (MCE) is often very cumbersome, because the experimental material data sets are incomplete or slightly erroneous, so that the obtained numerical results do not even fulfill energy conservation laws. In this article a phenomenological approach of modeling second-order magnetocaloric material properties is proposed, which allows highest accuracy in numerous kinds of numerical simulation processes. The presented model substance is also ideal for standardization purposes of physical modeling and numerical simulations of the operation of magnetic heaters, refrigerators and energy conversion machines.
Composite to Metal Joints for the ARPA Man-Rated Demonstration Article (1995)

The design, analysis and testing of composite-to-metal joints for the ARPA Man-Rated Demonstration Article are discussed. The first is a composite-to-titanium sphere joint designed to react sphere membrane stress with block compression loading. A series of uniaxial compression tests to simulate this joint assembly was conducted. Test results successfully demonstrated the ability of the joint to withstand block compression loading even in the presence of assembly fitup gaps. A polymer shimming material (Hysol EA9394) was also evaluated as a means to fill potential fitup gaps and was found to effectively reduce stress concentrations resulting from the gaps. The second joint discussed is one between 120-degree segments that make up a stiffener ring for a ringstiffened composite cylinder. Joint design includes Hysol EA9394, boltedon titanium splice plates, and bondedon thermoset flange straps. 2D joint tests, single stiffener tests, and sub-scale ring-stiffened cylinder hydrostatic tests to validate the joint design are described.
Prediction of metachronous multiple primary cancers following the curative resection of gastric cancer (2013)

Patients at high risk of developing metachronous MPC after curative resection of GC were identified. Individual risk of developing metachronous MPC could be predicted by a novel nomogram. Further external validation with independent patient cohorts is required to improve the accuracy of prediction.
Deep Learning in Human Activity Recognition with Wearable Sensors: A Review on Advances (2021)

Mobile and wearable devices have enabled numerous applications, including activity tracking, wellness monitoring, and human--computer interaction, that measure and improve our daily lives. Many of these applications are made possible by leveraging the rich collection of low-power sensors found in many mobile and wearable devices to perform human activity recognition (HAR). Recently, deep learning has greatly pushed the boundaries of HAR on mobile and wearable devices. This paper systematically categorizes and summarizes existing work that introduces deep learning methods for wearables-based HAR and provides a comprehensive analysis of the current advancements, developing trends, and major challenges. We also present cutting-edge frontiers and future directions for deep learning-based HAR.
Optic Disc Identification Methods for Retinal Images (2014)

Presented are the methods proposed by authors to identify and model the optic disc in colour retinal images. The first three our approaches localized the optic disc in two steps: a) in the green component of RGB image the optic disc area is detected based on texture indicators and pixel intensity variance analysis; b) on the segmented area the optic disc edges are extracted and the resulted boundary is approximated by a Hough transform. The last implemented method identifies the optic disc area by analysis of blood vessels network extracted in the green channel of the original image. In the segmented area the optic disc edges are obtained by an iterative Canny algorithm and are approximated by a circle Hough transform.
Mesomorphic Schiff's Bases Derived from p-Acetozyl-, p-n-Butyl-, and p-n-Butozy-Anilines (1972)

Abstract This note describes thirty-three new Schiff's bases which for structural reasons(1) were expected to show nematic phases of low thermal stability. In summary, the following trends seem apparent from the data listed in Tables 1, 2 and 3 for the [pacute]-acetoxy-, [pacute]-n-butyl- and [pacute]-n-butoxy anils, respectively.
Comparison of Different Calibration Techniques by Laser Induced Breakdown Spectroscopy in Bakery Products&nbsp; (2020)

<title>Abstract</title> Laser induced breakdown spectroscopy (LIBS) is a rapid optical spectroscopy technique for elemental determination, which has been used for quantitative analysis in many fields. However, the calibration involving atomic emission intensity and sample concentration, is still a challenge due to physical-chemical matrix effect of samples and fluctuations of experimental parameters. To overcome these problems, various chemometric data analysis techniques have been combined with LIBS technique. In this study, LIBS was used to show its potential as a routine analysis for Na measurements in bakery products. A series of standard bread samples containing various concentrations of NaCl (0.025%–3.5%) was prepared to compare different calibration techniques. Standard calibration curve (SCC), artificial neural network (ANN) and partial least square (PLS) techniques were used as calibration strategies. Among them, PLS was found to be more efficient for predicting the Na concentrations in bakery products with an increase in coefficient of determination value from 0.961 to 0.999 for standard bread samples and from 0.788 to 0.943 for commercial products.
An empirically derived short form of the Hypoglycaemia Fear Survey II (2016)

The short form of the Hypoglycaemia Fear Survey II is an important first step in more efficiently measuring fear of hypoglycaemia. Future prospective studies are needed for further validity testing and exploring the survey's applicability to different populations.
Staphylococcal Infection of a Starr–Edwards Prosthesis, with Fatal Obstruction of the Mitral Valve (1965)

IN recent years there has been increasing use of artificial cardiac valves such as the ball valve described by Starr and Edwards¶ in 1961. This report describes a patient with a Starr—Edwards prosthesis who died from occlusion of the mitral valve by thrombus and bacterial vegetations eleven months after operation.Case ReportA 46-year-old woman was admitted to the Johns Hopkins Hospital for evaluation of fever on July 15, 1963. Twenty-three years previously mitral stenosis had been diagnosed, and in 1956 valvulotomy was performed. Five years later cardiac failure recurred, and atrial fibrillation developed. A markedly stenotic mitral valve was . . .
Discovery of a Potent, Selective, and Brain-Penetrant Small Molecule that Activates the Orphan Receptor GPR88 and Reduces Alcohol Intake (2018)

The orphan G-protein-coupled receptor GPR88 is highly expressed in the striatum. Studies using GPR88 knockout mice have suggested that the receptor is implicated in alcohol seeking and drinking behaviors. To date, the biological effects of GPR88 activation are still unknown due to the lack of a potent and selective agonist appropriate for in vivo investigation. In this study, we report the discovery of the first potent, selective, and brain-penetrant GPR88 agonist RTI-13951-33 (6). RTI-13951-33 exhibited an EC<sub>50</sub> of 25 nM in an in vitro cAMP functional assay and had no significant off-target activity at 38 GPCRs, ion channels, and neurotransmitter transporters that were tested. RTI-13951-33 displayed enhanced aqueous solubility compared to (1 R,2 R)-2-PCCA (2) and had favorable pharmacokinetic properties for behavioral assessment. Finally, RTI-13951-33 significantly reduced alcohol self-administration and alcohol intake in a dose-dependent manner without effects on locomotion and sucrose self-administration in rats when administered intraperitoneally.
Technology insertion problems and solutions for aging avionics systems (2002)

As military budgets shrink, military contractors are under increasing pressure to produce high performance, low cost systems. For new weapons systems, this pressure generally has meant exploiting the economies of scale of standardized, military-approved microprocessor chips. As currently-deployed systems age, an equally great need exists to tap these same economies of scale to extend the useful lives of older defense systems in a cost-effective manner. This paper discusses the design methodology used to upgrade the radar system aboard a tactical fighter plane. In particular, it will concentrate on those techniques used to provide hardware flexibility while meeting the design goal of form, fit, and functional compatibility with the currently fielded radar system.
From farm to fork: lipid oxidation in fish products. A review (2016)

Lipid oxidation is a very complex and important event threatening the quality of foods especially of those containing highly unsaturated fats. Fish are the main source of polyunsaturated fatty acids that, unfortunately, are highly susceptible to degradation process, such as oxidation. Fish supply chain generally involves many steps and each of them together with their interaction might play a central role in muscle quality maintenance. From this review emerged that antioxidants supplementation diet can play a central role to limit the detrimental effects of stress (pre-slaughter or at killing) and storage. In this sense, lycopene shows the best antioxidant activity during stressful conditions while α-tocopherol acts preferentially in long-term frozen storage. Stress just before or at slaughter can greatly threaten flesh quality both immediately and after storage by inducing numerous metabolic pathways, that often involve the production of very reactive molecular species, such as hydroperoxides. A common operation such as bleeding can significantly reduce both reactive molecules and haemoglobin (Hb), which is recognised as a great pro-oxidant. Temperature and duration are two critical points of storage phase which has to be considered even by consumers. Frozen storage at very low temperatures (−30 °C, −40 °C) confirms to be the best storage practise. Finally, cooking can compromise aromatic profile of cooking fillets. Thus, feeding antioxidant, reducing stress both during pre-slaughter practise and at killing, good storage practises, if associated with an appropriate cooking method (low temperature, short time) seems to be the clues for preserving the fragile lipid fraction from farm to fork.
Neuro-Ophthalmic Literature Review (2017)

Doctor…what about my double vision?"
UWB/LiDAR Fusion For Cooperative Range-Only SLAM (2019)

We equip an ultra-wideband (UWB) node and a 2D LiDAR sensor a.k.a. 2D laser rangefinder on a mobile robot, and place UWB beacon nodes at unknown locations in an unknown environment. All UWB nodes can do ranging with each other thus forming a cooperative sensor network. We propose to fuse the peer-to-peer ranges measured between UWB nodes and laser scanning information, i.e., range measured between robot and nearby objects/obstacles, for simultaneous localization of the robot, all UWB beacons and LiDAR mapping. The fusion is inspired by two facts: 1) LiDAR may improve UWB-only localization accuracy as it gives a more precise and comprehensive picture of the surrounding environment; 2) on the other hand, UWB ranging measurements may remove the error accumulated in the LiDAR-based SLAM algorithm. Our experiments demonstrate that UWB/LiDAR fusion enables drift-free SLAM in real-time based on ranging measurements only.
Monitoring of Photodegradation Process of Various Benzothiazoles by HPLC and UV Spectrometry: Application of LC-MS in Photoproduct Identification (2009)

Abstract A simple gradient elution reverse-phase liquid chromatography method, together with UV spectrometry, was used for monitoring of the photodegradation process of various benzothiazoles. A combination of liquid chromatography (LC) with a photodiode array detector (PDA) and an electrospray ionization mass spectrometry detector (ESI-MS) was further used for identification of photoproducts. Separation was accomplished on a Hypersil ODS column with acetonitrile-water gradient at detection wavelength of 255 nm. Formic acid or ammonium acetate were used as additives in the positive or negative mode of ionization with the ESI-MS detector.
Association between historically high frequencies of neural tube defects and the humanT homologue of mouseT (Brachyury) (2000)

The human T developmental gene has been implicated in the etiology of neural tube defects (NTDs) on the basis both of mouse studies of its homologue, T (Brachyury), and of allelic association in a Caucasian population. We have investigated the frequency of the T allelic variant TIVS7-2 in 218 Irish NTD case-parent triads. This population showed the same trend as previously reported, with an excess of the TIVS7-2 allele among cases. Log-linear modeling of case and maternal genotypic effects within families indicated that TIVS7-2 was elevated in cases (relative risk, RR = 1.36) but not in mothers (RR = 0.91). The TIVS7-2 allele is markedly associated with cases born before 1980 (RR = 2.09; CI = 1.23-3.55; corrected p = 0.030), but not with more recent cases (RR = 0.92). Cases carrying a TIVS7-2 allele did not show any increased tendency to be homozygous for the thermolabile variant of the folate-dependent enzyme 5,10-methylene tetrahydrofolate reductase, which is an established genetic risk factor for NTDs. Since the incidence of NTDs has declined markedly in Ireland over the last few decades, we suggest that the T-associated risk is potentiated by nutritional or environmental risk factor(s), the impact of which have been diminishing over time.
ICA fusion approach based on fuzzy using in eddy current pulsed thermography (2016)

Eddy current pulsed thermography (ECPT) has been applied for a wide range of conductive materials. The enhancement of thermography to detect the defects is also important. This paper proposes an independent component analysis (ICA) fusion method based fuzzy algorithm to process the thermography ima ges. In ICA, three kinds of contrast function are applied to obtain the different ICs respectively. Then, the corresponding fused ICs are obtained by the fuzzy fusion algorithm. Meanwhile, the kurtosis of each ICs before and after fusion are computed to evaluate the performance of the proposed method. In addition, an experiment is utilized to show the benefits of the proposed ICA fusion method.
Zinc Protoporphyrin Past, Present, and Futurea (1987)

The course of zinc protoporphyrin research has progressed at an increasingly rapid pace on several fronts. A variety of biochemical and clinical evidence viewed in toto now suggests that ferrochelatase catalyzes zinc protoporphyrin formation in states of relative iron-deficient erythropoiesis and in lead-inhibited iron metabolism. Furthermore, a redefinition of the relationship of zinc protoporphyrin to certain other parameters of iron status has been made based upon changes during the earliest states of iron depletion. These clinical studies show that the zinc protoporphyrin level and the ferritin level vary in concert but that changes in the percent transferrin saturation and in the hematocrit results are less consistent. Thus zinc protoporphyrin and ferritin are closely linked metabolically such that iron-deficient erythropoiesis becomes an initial manifestation of iron depletion. The measurement and expression of results as mumoles zinc protoporphyrin/mole heme have improved the quality of results, partly by the elimination of the assumed hematocrit designed into existing instruments. Other refinements in hematofluorometry technology have permitted exploration of the potentially extensive applications of zinc protoporphyrin measurements for lead surveillance and diagnosis, blood banking, pediatrics, obstetrics, sports medicine, and other clinical situations where a very sensitive, cost-effective indication of iron status is required.
<title>Optical properties of metallophthalocyanines in solution and in a sol-gel matrix</title> (1997)

The sol-gel method is convenient for preparing amorphous transparent oxides with a wide range of optical properties including laser action, optical gain, phosphorescence, SHG and other non-linear effects. The sol-gel method was used to produce sol-gel samples using metallophthalocyanines. From metallophthalocyanines we used Cu (II) phthalocyanine (beta) - form, Ni (II) phthalocyaninetetrasulfonic acid, tetrasodium salt, Cu (II) 3,10,17,24-tetra-tert-butyl-1,8,15,22-tetrakis (dimethylamino)-29H, 31H-phthalocyanine, Zn 1,4,8,11,15,18,22,25-octabutoxy- 29H,31H-phthalocyanine Ni (II) 5,9,14,18,23,27,32,36-octabutoxy- 2,3-napthalocyanine and Cu (II) 5,9,14,18,23,27,32,36-octabutoxy-2,3-napthalocyanine. In our paper we report and discuss the results obtained from the measurements of the index of refraction using the prism coupling technique, absorption spectra and non-linear transmission measurements using picosecond laser pulses. The absorption spectras of Cu, Zn and Ni phthalocyanines in solution and sol-gel matrix showed decomposition. We found optical limiting after 0.2 J/cm<SUP>2</SUP> in Ni (II) phthalocyaninetetrasulfonic acid, tetrasodium salt solution; glass samples showed no optical limiting. The mean of the index of refraction measured for all the (beta) -Cu phthalocyanine samples was 1.42. No birefringency was found.
Bromide Alkoxides of Tantalum (1967)

Abstract Reactions of tantalum pentaalkoxides (ethoxide, isopropoxide and tertiarybutoxide with acetyl bromide give the products: Ta(OEt) 4 Br; Ta(OEt) 3 Br 2 ; Ta(OEt) 2 Br 3 · MeCO 2 Et; Ta(OEt)Br 4 · MeCO 2 Et; Ta(OPr 1 ) 4 Br; Ta(OPr 1 ) 3 Br 2 ; Ta(OPr 1 ) 2 Br 3 · MeCO 2 Pr 1 ; TaOBr 3 . MeCo 2 Pr 1 ; Ta(OBu t ) 4 Br and TaOBr 3 · MeCO 2 Bu t . These products were found to be viscous liquids or solids. All these bromide alkoxides except the tertiarybutoxide derivatives were found to be soluble in benzene. The tetraalkoxide monobromide derivatives could either be distilled or sublimed unchanged under reduced pressure. The tetraalkoxide monobromide derivative was found to be dimeric in boiling benzene.
Reactions of (Triphenylphosphine)gold(I) Enolates and Homoenolates (1988)

Abstract Some reactions of (triphenylphosphine)gold(I) enolates and homoenolates, which are respectively prepared by the reaction of trimethylsilyl ethers of enols and cyclopropanols with (triphenylphosphine)gold(I) chloride in the presence of cesium fluoride, are described. The aldol reaction of (triphenylphosphine)gold(I) enolates with carbonyl compounds is efficiently promoted by Lewis acids such as titanium tetrachloride and diethylaluminum chloride to produce β-hydroxy carbonyl compounds. (Triphenylphosphine)gold(I) enolate reacts with phenyl acetylene to afford (triphenylphosphine)gold(I) phenylacetylide in good yield. Reaction of (benzoylmethyl)(triphenylphosphine)gold(I) (3a) with chlorotrimethylsilane produces α-(trimethylsilyloxy)styrene and (triphenylphosphine)gold(I) chloride, which is the reverse of the formation of 3a. Gold(I) enolate undergoes an isocyanide insertion reaction into the linkage of carbon and gold. (2-Benzoylethyl)(triphenylphosphine)gold(I) reacts with 2-methyl-2-propanethiol to afford (triphenylphosphine)gold(I) t-butyl sulfide together with propiophenone.