gebhart/patrepeval huggingface dataset:
Novel inorganic oxide pillared .gamma.-zirconium phosphate formed by intercalation of octameric siloxanes (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNovel inorganic oxide pillared .gamma.-zirconium phosphate formed by intercalation of octameric siloxanesThierry Cassagneau, Deborah J. Jones, and Jacques RoziereCite this: J. Phys. Chem. 1993, 97, 34, 8678–8680Publication Date (Print):August 1, 1993Publication History Published online1 May 2002Published inissue 1 August 1993https://pubs.acs.org/doi/10.1021/j100136a002https://doi.org/10.1021/j100136a002research-articleACS PublicationsRequest reuse permissionsArticle Views191Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Biologics in inflammatory bowel disease: what are the data? (2015)

Management with biologics in IBD patients is well validated by high-quality clinical trials.
Use of 3-Dimensional Printing at the Point-of-Care to Manage a Complex Wound in Hemifacial Necrotizing Fasciitis: A Case Report (2022)

Abstract Background: Complex facial wounds can be difficult to stabilize due to proximity of vital structures. We present a case in which a patient-specific wound splint was manufactured using computer assisted design and three-dimensional printing at the point-of-care to allow for wound stabilization in the setting of hemifacial necrotizing fasciitis. We also describe the process and implementation of the United States Food and Drug Administration Expanded Access for Medical Devices Emergency Use mechanism. Case Presentation: A 58-year-old female presented with necrotizing fasciitis of the neck and hemiface. After multiple debridements, she remained critically ill with poor vascularity of tissue in the wound bed and no evidence of healthy granulation tissue and concern for additional breakdown towards the right orbit, mediastinum, and pretracheal soft tissues, precluding tracheostomy placement despite prolonged intubation. A negative pressure wound vacuum was considered for improved healing, but proximity to the eye raised concern for vision loss due to traction injury. As a solution, under the Food and Drug Administration’s Expanded Access for Medical Devices Emergency Use mechanism, we designed a three-dimensional printed, patient-specific silicone wound splint from a CT scan, allowing the wound vacuum to be secured to the splint rather than the eyelid. After five days of splint-assisted vacuum therapy, the wound bed stabilized with no residual purulence and developed healthy granulation tissue, without injury to the eye or lower lid. With continued vacuum therapy, the wound contracted to allow for safe tracheostomy placement, ventilator liberation, oral intake, and hemifacial reconstruction with a myofascial pectoralis muscle flap and a paramedian forehead flap one month later. She was eventually decannulated and at six-month follow-up has excellent wound healing and periorbital function. Conclusions: Patient-specific, three-dimensional printing is an innovative solution that can facilitate safe placement of negative pressure wound therapy adjacent to delicate structures. This report also demonstrates feasibility of point-of-care manufacturing of customized devices for optimizing complex wound management in the head and neck, and describes successful use of the United States Food and Drug Administration’s Expanded Access for Medical Devices Emergency Use mechanism.
ZB-06, a vaginal film containing an engineered human contraceptive antibody (HC4-N), demonstrates safety and efficacy in a phase 1 postcoital test and safety study (2023)

A single dose of the ZB-06 film applied before intercourse was safe and met efficacy surrogate benchmarks of excluding progressively motile sperm from ovulatory cervical mucus. These data indicate that ZB-06 is a viable contraceptive candidate warranting further development and testing.
Local Area Network Technology Applied to Automotive Electronic Communications (1985)

The purpose of this paper is to provide a tutorial on the current uses of digital communications in General Motors (GM) vehicle products. Existing GM vehicle communication systems are reviewed, their characteristics are described, and the future development trends of such systems are discussed. Long-term development of automotive digital communications will require a more complete understanding of the technologies applied. Local area network technology is proving to be very effective in lowering the cost of communication in land-based systems, due to the rapid growth and development of low-cost computing and data storage. Vehicle designers are now applying many of these same technologies to reduce the life cycle costs of increasingly complex electrical/electronic systems.
La distraction ostéogénique en chirurgie orthopédique de la mandibule (2005)

Distraction osteogenesis is a bone creating procedure that can contribute materially to the treatment of Class II dento-skeletal disorders where the mandible is under-sized. Still, the serious commitments this treatment demands and the unpredictability of its occlusal results oblige practitioners to pinpoint precisely the indications for its use. We now believe that distraction osteogenesis can beneficially be employed for: 1--Adults with Class II malocclusions, a small mandible, and a lack of harmony between tooth and jaw size. This bone growing technique makes it possible to treat these patients without the extraction of premolars that would have been necessary in the traditional preparation for orthognathic surgery. 2--Patients whose mandibles are diminished in size in the area of the symphasis. Distraction osteogenesis of this anterior segment is the only way they can be treated without reduction of tooth structure or excessive labial tipping of teeth. 3--Some patients with short, or moderately short rami. We do not, at this time, believe that distraction osteogenesis is indicated for the treatment of any other kind of dento-facial deformity. But, in the future, improvement of surgical techniques and the miniaturization of appliances will doubtless extend its scope.
Entropy-Based Dynamic Graph Embedding for Climate Change Detection (2020)

Abstract Climate change is a severe problem caused by abnormal climate events. The existing methods for detecting climate changes utilize statistical models to analyze the atmospheric temperature, but a climate event commonly comprises multiple meteorological data. To detect climate changes using meteorological data, we propose a novel dynamic graph embedding model based on graph entropy called EDynGE. A climate event is denoted as a graph, in which the nodes indicate meteorological data and edges indicate the correlation between nodes. Graph entropy measures the information of the climate event, and the EDynGE model clusters graphs based on graph entropy. We conducted experiments on real meteorological data. The results showed that the number of days of abnormal climate events has increased by 304.5 days in the past 30 years.
P1‐153: The relationship between olfactory identification and memory and Abeta burden in Alzheimer's disease, mild cognitive impairment and healthy aging: A PIB‐PET study (2008)

Olfactory deficits as well as increased Beta-amyloid (Aβ) burden are well documented in people with mild cognitive impairment (MCI) and both may be predictive of Alzheimer's disease (AD). Although olfactory deficits are associated with neuropathology in medial temporal lobe structures, research has not clarified whether the accumulation of Aβ in areas central to olfactory processing is directly related to the observed olfactory deficits in AD and MCI. This is the first study to explore whether olfactory identification and memory are related to in vivo measures of Aβ burden using PIB PET in MCI, AD, and healthy elderly (HC) participants. Eleven HC, 17 MCI, and 14 AD participants performed unirhinal olfactory identification and memory tests and completed a neuropsychological battery and PIB PET scanning. AD patients performed worse on olfactory identification than people with MCI, who performed worse than HCs. Aβ burden in people with AD was greater than in people with MCI, and this was greater than in HCs. Olfactory memory did not differ across the groups. A significant correlation between PIB binding in areas central to olfaction and olfactory identification on the left nostril (r= –.38) was eliminated once diagnostic status was controlled in a multiple regression analysis. Similarly, there was no difference in olfactory identification abilities between participants who were PIB positive and those who were PIB negative once diagnosis was controlled. Both Aβ and olfactory identification performance discriminated between the groups, and a relationship was evident between the two factors. This relationship appears to be mediated by diagnostic status, however, raising the possibility that any contribution made by amyloid deposition towards AD-related olfactory identification deficits is indirect in nature.
A Novel Technique of Vacuum-assisted Wound Closure That Functions as a Delayed Primary Closure. (2007)

﻿Contaminated midline abdominal wounds are often left open and allowed to close via secondary intention to prevent surgical site infections. Negative pressure wound therapy (NPWT) devices have decreased time of healing by secondary intention when compared to the prior standard of moist dressings. The authors report a modification of NPWT that utilizes the unique characteristics of the negative pressure system to achieve delayed primary closure while preventing surgical site infections by continuously draining the wound effluent.
Lubrication Enhancement for UHMWPE Sliding Contacts through Surface Texturing (2014)

Considered a self-lubricating, abrasion-resistant biomaterial, ultra-high-molecular-weight polyethylene (UHMWPE) has become the most common acetabular cup material used in artificial hip joints. Artificial hip joints exist primarily in the boundary and mixed regimes, which can lead to premature failure due to surface wear, debris generation, and subsequent osteolysis. The tendency of failure due to the generation of wear debris has turned the hip problem into a complex tribological challenge with a focus on abrasion-resistant surfaces. Surface texturing in the form of microdimples has been shown in other applications to provide enhanced wear resistance through the trapping of wear debris and through the enhancement of fluid pressures to levels that promote mixed- to full-film lubrication even at low speeds. The objective of this investigation is to explore the potential for surface texturing of UHMWPE sliding contacts in enhancing the lubrication regimes present in total hip replacements. Surface textures were created using a mechanical micromachining process, and experiments were conducted on a pin-on-disk tribometer under lubricated conditions present in the hip for textured and untextured samples. Results show that the surface textures were able to reduce friction by up to 50% over that observed with untextured UHMWPE samples, with evidence that suggests a regime shift from boundary lubrication to mixed and full-film lubrication as the primary mechanism for friction reduction.
Crystal and molecular structure of thalidomide, N-(α-glutarimido)-phthalimide (1971)

Crystals of the N-(α-glutarimido)-derivative of phthalimide (Thalidomide), C13H10N2O4, are monoclinic, space group P21/n, with a= 8·233 (1), b= 10·070(2), c= 14·865(2)Å, β= 102·53(2)°, and Z= 4. The structure has been determined by direct methods using diffractometer data; full-matrix least-squares refinement has reduced R to 0·053 for 1855 observed reflections, which were corrected for absorption. The phthalimide residue is significantly non-planar, while the glutarimido-moiety approximates a half-chair conformation; the central N–C bond is equatorial. The angle between the mean phthalimide and glutarimido-planes is 81°. Pairs of centrosymmetrically related molecules form hydrogen-bonded dimers through N–H ⋯ O contacts of 2·928 Å between glutarimido-residues.
Convex Optimization for Spring Design of Parallel Elastic Actuators (2022)

Elastic actuation can improve human-robot interaction and energy efficiency for wearable robots. Previous work showed that the energy consumption of series elastic actuators can be a convex function of the series spring compliance. This function is useful to optimally select the series spring compliance that reduces the motor energy consumption. However, series springs have limited influence on the motor torque, which is a major source of the energy losses due to the associated Joule heating. Springs in parallel to the motor can significantly modify the motor torque and therefore reduce Joule heating, but it is unknown how to design springs that globally minimize energy consumption for a given motion of the load. In this work, we introduce the stiffness design of linear and nonlinear parallel elastic actuators via convex optimization. We show that the energy consumption of parallel elastic actuators is a convex function of the spring stiffness and compare the energy savings with that of optimal series elastic actuators. We analyze robustness of the solution in simulation by adding uncertainty of 20% of the RMS load kinematics and kinetics for the ankle, knee, and hip movements for level-ground human walking. When the winding Joule heating losses are dominant with respect to the viscous losses, our optimal PEA designs outperform SEA designs by further reducing the motor energy consumption up to 63%. Comparing to the linear PEA designs, our nonlinear PEA designs further reduced the motor energy consumption up to 31%. From our convex formulation, our global optimal nonlinear parallel elastic actuator designs give two different elongation-torque curves for positive and negative elongation, suggesting a clutching mechanism for the final implementation. In addition, the different torque-elongation profiles for positive and negative elongation for nonlinear parallel elastic actuators can cause sensitivity of the energy consumption to changes in the nominal load trajectory.
Quantum vortex dynamics in two-dimensional neutral superfluids (2010)

We derive an effective action for the vortex-position degree of freedom in a superfluid by integrating out condensate phase- and density-fluctuation environmental modes. When the quantum dynamics of environmental fluctuations is neglected, we confirm the occurrence of the vortex Magnus force and obtain an expression for the vortex mass. We find that this adiabatic approximation is valid only when the superfluid droplet radius $R$, or the typical distance between vortices, is very much larger than the coherence length $\ensuremath{\xi}$. We go beyond the adiabatic approximation numerically, accounting for the quantum dynamics of environmental modes and capturing their dissipative coupling to condensate dynamics. For the case of an optical-lattice superfluid, we demonstrate that vortex motion damping can be adjusted by tuning the ratio between the tunneling energy $J$ and the on-site interaction energy $U$. We comment on the possibility of realizing vortex-Landau-level physics.
Simultaneous image fusion and denoising with adaptive sparse representation (2014)

In this study, a novel adaptive sparse representation (ASR) model is presented for simultaneous image fusion and denoising. As a powerful signal modelling technique, sparse representation (SR) has been successfully employed in many image processing applications such as denoising and fusion. In traditional SR‐based applications, a highly redundant dictionary is always needed to satisfy signal reconstruction requirement since the structures vary significantly across different image patches. However, it may result in potential visual artefacts as well as high computational cost. In the proposed ASR model, instead of learning a single redundant dictionary, a set of more compact sub‐dictionaries are learned from numerous high‐quality image patches which have been pre‐classified into several corresponding categories based on their gradient information. At the fusion and denoising processes, one of the sub‐dictionaries is adaptively selected for a given set of source image patches. Experimental results on multi‐focus and multi‐modal image sets demonstrate that the ASR‐based fusion method can outperform the conventional SR‐based method in terms of both visual quality and objective assessment.
Repetitive learning control: a Lyapunov-based approach (2002)

In this paper, a learning-based feedforward term is developed to solve a general control problem in the presence of unknown nonlinear dynamics with a known period. Since the learning-based feedforward term is generated from a straightforward Lyapunov-like stability analysis, the control designer can utilize other Lyapunov-based design techniques to develop hybrid control schemes that utilize learning-based feedforward terms to compensate for periodic dynamics and other Lyapunov-based approaches (e.g., adaptive-based feedforward terms) to compensate for nonperiodic dynamics. To illustrate this point, a hybrid adaptive/learning control scheme is utilized to achieve global asymptotic link position tracking for a robot manipulator.
Contributions of Individual Nucleotides to Tertiary Binding of Substrate by a Pneumocystis carinii Group I Intron (2000)

Pneumocystis carinii is a mammalian pathogen that infects and kills immunocompromised hosts such as cancer and AIDS patients. The LSU rRNA precursor of P. carinii contains a conserved group I intron that is an attractive drug target because humans do not contain group I introns. The oligonucleotide r(AUGACU), whose sequence mimics the 3'-end of the 5'-exon, binds to a ribozyme derived from the intron with a K(d) of 5.2 nM, which is 61000-fold tighter than expected from base-pairing alone [Testa, S. M., Haidaris, G. C., Gigliotti, F., and Turner, D. H. (1997) Biochemistry 36, 9379-9385]. Thus, oligonucleotide binding is enhanced by tertiary interactions. To localize interactions that give rise to this tertiary stability, binding to the ribozyme has been measured as a function of oligonucleotide length and sequence. The results indicate that 4.3 kcal/mol of tertiary stability is due to a G.U pair that forms at the intron's splice junction. Eliminating nucleotides at the 5'-end of r(AUGACU) does not affect intron binding more than expected from differences in base-pairing until r((___)ACU), which binds much more tightly than expected. Adding a C at the 5'- or 3'-end that can potentially form a C-G pair with the target has little effect on binding affinity. Truncated oligonucleotides were tested for their ability to inhibit intron self-splicing via a suicide inhibition mechanism. The tetramer, r((__)GACU), retains similar binding affinity and reactivity as the hexamer, r(AUGACU). Thus oligonucleotides as short as tetramers might serve as therapeutics that can use a suicide inhibition mechanism to inhibit self-splicing. Results with a phosphoramidate tetramer and thiophosphoramidate hexamer indicate that oligonucleotides with backbones stable to nuclease digestion retain favorable binding and reactivity properties.
Compressive image sensor technique with sparse measurement matrix (2016)

This paper presents compressive image sensor techniques based on sparse measurement matrices. Existing compressive sensing (CS) CMOS image sensors use dense random measurement matrices, which face the challenges of excessive hardware overhead and large signal swing requirement. The sparse measurement matrices proposed in this paper dramatically simplify the circuit implementation and relax the signal swing requirement. The validity of the proposed sparse measurement matrices is justified and their performances are compared with results reported in literature as well as results obtained using dense random measurement matrices in our own study. Circuit techniques to implement CS image sensors based on sparse measurement matrices are discussed and a 250×250 Pixel image sensor with a compression rate of 250/62 is designed using a 0.13 μm CMOS technology. Circuit simulation shows that the image sensor can achieve a peak signal to noise ratio of 31.7dB.
A Satisficing Bi-Directional Model Transformation Engine using Mixed Integer Linear Programming. (2013)

The use of model transformation in software engineering has increased significantly during the past decade, with the ability to rapidly transform models and ensure consistency between those models being a key property of Model Driven Architecture. However, these approaches can be applied to a wide variety of different model types and some of these models and associated transformations require different semantics than those popularised by current model transformation tools. Specifically, current relational model transformation languages typically prioritise matching relation patterns in the source model over creating a target model that is compliant with its meta-model. In this paper we describe a relational model transformation engine implemented as a series of Mixed Integer Linear Programs (MILP). This engine has a key novel feature; it prioritises target model compliance with its meta-model by considering multiple interpretations of applying the transformation specification in order to ensure a correct target model is generated. In this paper the MILP transformation engine and the representations it uses are described, followed by the results of applying it to examples of varying complexity.
Influence of alternansucrase-derived oligosaccharides and other carbohydrates on α-galactosidase and α-glucosidase activity in Bifidobacterium adolescentis (2007)

Fundamental knowledge of enzyme activity in Bifidobacterium may aid in the design of more effective prebiotics and may also help identify enzyme indicators of metabolic activity when assessing influence within the intestine.