gebhart/patrepeval huggingface dataset:
A distributed interference-aware load balancing algorithm for LTE multi-cell networks (2012)

Within a cellular wireless network the unbalanced user load among cells, together with Inter-Cell-Interference (ICI), constitute major factors responsible for poor overall performance. In the current work, a novel decentralized algorithm for Load Balancing in the downlink is suggested. Two are the major novelties in the analysis. (A) The algorithm is based on the solution of a mixed integer optimization problem solved using Lagrangian but not Linear Programming relaxation, which allows the solution to be binary for the user assignment variables. (B) Its implementation is based on exchange of certain prices among base stations and allows each of them to make choices individually without the aid of a central controller. The cell handover parameters are further adequately adjusted to enforce cell-edge users to migrate to their optimal base station. The algorithm aims at optimally balancing the load, while at the same time guaranteeing low levels of ICI. Its performance is evaluated through simulations, which illustrate the improvements provided on aggregate system utility.
Fabrication of a Nanosize Pattern Embedded Plastic Chip via an Injection Molding Method for Application to an Optical Biosensor (2010)

Abstract We demonstrate a commercialized injection molding method for nano patterning of polymethyl methacrylate (PMMA) for the purpose of mass production of a label-free optical biosensor chip. Scanning electron microscope (SEM) images clearly show uniform nanopattern transfer on the plastic chip fabricated by an injection molding method. A uniformly deposited silicon nitride layer having a high refractive index by a plasma enhanced chemical vapor deposition (PECVD) technique is also observed. A unique characterization method is described wherein optical resonance reflection is used accurately and quickly to characterize the geometrical sensor structure. The authors anticipate that this robust method will provide an excellent means of producing an optical resonance reflection biosensor (ORRB).
Congenital anomalies and early neonatal mortality: A tertiary hospital study. (2022)

Background: The prevalence of congenital anomalies at birth is underestimated in developing countries due to the unavailability of perinatal diagnostic tests or accurate medical records. The prevalence of congenital defects may help to establish a baseline, track changes over time, and uncover etiological clues. Objectives: This study aims to evaluate the prevalence and types of major congenital anomalies in one of the main referral tertiary centers in Baghdad, highlighting the parent and neonatal characteristics and assessing the mortality rate in this group of patients. Patients and Methods: A prospective cohort study was conducted in Baghdad Teaching Hospital during the period between May 2017 and May 2018. Total deliveries were 6553, all live neonates with congenital anomalies were included regardless of their gestational age or birth weight. The patient's hospital notes were reviewed for the patient's characteristics, parentage, maternal chronic disease, and drug history, and other study parameters. The early neonatal outcome was assessed within 7 days of the delivery. Results: The prevalence of congenital malformations was 21.5 per 1000 birth with the highest frequent anomaly affecting the nervous system (41.1%) followed by multiple syndromic malformations (12.8%) and digestive system (11.3%). The mean maternal age was 27.8 (±7.8) ranging from 14-47. The rate of diseased mothers was 18.4%, only half of them were on regular medications. Out of a total of 399 early neonatal death during the study period, death due to congenital malformations constituted 19.8%. Congenitally deformed patients died at a rate of 56%, which was significantly associated with gestational age and neonatal birth weight. Conclusion: The prevalence of congenital abnormalities has increased in the same hospital over the last decade. Mortality rate of these patients is high and associated with gestational age and birth weight. It is critical to test for congenital malformations early in pregnancy, particularly for high-risk parents with advanced age, consanguinity, and history of congenital anomalies.
ChemInform Abstract: Phorbazoles A‐D, Novel Chlorinated Phenylpyrrolyloxazoles from the Marine Sponge Phorbas aff. clathrata. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Supplementary Table 1 from An Essential Requirement for the SCAP/SREBP Signaling Axis to Protect Cancer Cells from Lipotoxicity (2023)

&lt;p&gt;PDF File - 92K, Gene set enrichment analysis on the ten most statistically significant down-regulated metabolic pathways in SCAP loss-of-function cells.&lt;/p&gt;
Endovascular embolization of pterygoid arteriovenous malformation presented with cerebral intraparenchymal hemorrhage (2008)

【目的】稀な疾患である翼突筋部動静脈奇形の症例を経験したので，その治療経過を報告する．【方法】左被殻出血の病因検索中，主に顎動脈を流入動脈とする左翼突筋部動静脈奇形を認めた．血管撮影では左海綿静脈洞および左下錐体静脈洞が流出路の一部となっていたが，皮質静脈への逆流など，動静脈奇形が脳出血の病因であると強く示唆する所見はなかった．【結果】２回にわたる血管内塞栓術を行い，動静脈奇形を完全閉塞しえた．塞栓に際しては脳神経の栄養血管や内頸-外頸動脈の潜在的吻合に留意し，必要に応じて液体塞栓物質とコイルを使い分けることで合併症を避けることができた．【結論】頭蓋外，硬膜外に存在する頭頸部領域動静脈奇形の流出路として頭蓋内静脈系への逆行性流出路が形成されることがある．頭頸部領域動静脈奇形の血管内治療においては，頭蓋底部の血管解剖を理解したうえで血管撮影を読影し，慎重に塞栓を行う必要がある．
Improvements on the Properties of the In Situ MgB<sub>2</sub>/Fe Tapes Annealed by Spark Plasma Sintering Technique (2007)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
IMAGE CYTOMETRY FOR DNA ANALYSIS IN ENDOMETRIAL CARCINOMA CORRELATED WITH OTHER PROGNOSTIC PARAMETERS (1995)

We evaluated by static cytometry DNA ploidy parameters in 30 stage I-IV endometrial carcinomas and correlated these data with standard clinical-pathological features and disease-free period. We observed a direct correlation between either non-diploid DNA content and deeper myometrial invasion (p<0.02) or D.I.greater than or equal to 1.2 and M2-M3 tumors (p<0.009). The Kaplan Meier survival curves illustrate a more rapid relapse of disease associated with non-diploidy, high 5cExR, high level of proliferation and D.I.greater than or equal to 1.2. while Cox regression model gave relative hazards for disease recurrence of 4, 6, 3.7 and 2.1 for non-diploidy, D.I.greater than or equal to 1.2, high 5cExR and high level of proliferation respectively. This prospective study confirmed the prognostic value of DNA Index, and its usefulness in clinical practice especially in stage I cases, otherwise characterised by favourable standard prognostic factors, is discussed.
Dye structure–optical property correlations in near-infrared fluorescent core-shell silica nanoparticles (2009)

In this paper we report on dye structure–optical property correlations for a range of near-infrared emitting (NIR, 650–900 nm) fluorescent dyes in a 9–14 nm diameter core-shell silica particle architecture (C dots), including Cy5, Alexa Fluor 700, DY730, Alexa Fluor 750, and DY780. For each dye an apparent per-dye enhancement in fluorescence is observed over free dye in aqueous solution ranging from 1.2× to 6.6×, highlighting the versatility of the silica encapsulation approach. For the Cy5 and DY730 dye/particle sample pairs photobleaching was undertaken and revealed that the particles photobleach slower than the dyes. For a particular NIR dye series with identical chemical backbone, DY730, DY731, DY732, and DY734, we demonstrate that with increasing number of sulfonated substituent groups the per-dye brightness enhancement decreases. Finally, we show that in special cases, like Cy5, brightness enhancement of dyes in dots over free dye may be a combination of effects from dye conjugation chemistry and immobilization in the silica matrix. These results provide powerful design criteria for next generation optical probes for applications ranging from bioimaging to security.
Personalized Health and the Coronavirus Vaccines --Do Individual Genetics Matter? (2021)

This article assesses the role of recipient genetics to COVID-19 vaccine responses. Vaccines represent preventative interventions suitable to an immunogenetic perspective to predict how human variability will influence their safety and efficacy. The genetic polymorphism among individuals within any population can make possible that the immunity elicited by a vaccine is variable in length and strength. The same immune challenge (either virus or vaccine) could provoke partial, complete or even failed protection for some individuals treated under the same conditions. We review genetic variants and mechanistic relationships among chemokines, chemokine receptors, interleukins, interferons, interferon receptors, toll-like receptors, histocompatibility antigens, various immunoglobulins and major histocompatibility complex antigens. These are the targets for variation among macrophages, dendritic cells, Natural Killer cells, T- and B- lymphocytes, and complement. The acute nature of vaccine reactogenicity is reminiscent of the time course of adverse drug reaction mediated by the immune system. The variety of technology platforms (mRNA, viral vectors) utilized currently to produce vaccines against SARS-CoV-2 infections may each also trigger genetically distinct immune reactogenic profiles. With biobanking of recipient genomic DNA and serum immunoprofiling, global COVID-19 vaccinations could launch a new era of research and clinical translation in personalized health.
Primary Culture and Characterization of Enamel Organ Epithelial Cells (1998)

The cells of the enamel organ are programmed by signals such as growth factors and extracellular matrix components to differentiate and form dental enamel. To study how the enamel organ epithelial cells control enamel development, we have begun to characterize a primary porcine enamel organ epithelial cell culture system. The unerupted molars of 3 month old pigs were isolated, the cells were digested into a single cell suspension and grown in media either with or without serum. Expression of amelogenin and ameloblastin mRNA was monitored by RT PCR, and protein secretion was identified by immunohistochemistry. Cells grown in MEM formed a mixed cell population of epithelial- and fibroblast-like cells which grew past confluence, formed nodules, mineralized, and expressed low levels of amelogenin and ameloblastin protein. In LHC-9 media, which is selective for epithelial cells, the cells did not grow past confluence but secreted amelogenin and ameloblastin proteins more strongly. Cell viability was maintained in both serum-free and serum-containing media. However, in the serum-free media, cell proliferation proceeded slowly. Although cells grown in MEM mineralized, the mixed cell population may make studies of specific ameloblast-like cells more difficult. However, cells grown in a culture media selective for epithelial cells will require modifications such as cell immortalization to allow long term studies of cell regulation and interaction. In summary, we have established an enamel organ epithelial cell culture system which will enable us to study the role of ameloblasts in enamel matrix formation, ameloblast regulation, as well as cell-matrix interactions. Selection of specific culture conditions will depend on the questions being addressed in individual studies.
Positive nickel patch tests do not intensify positive reactions to adjacent patch tests with dichromate (2000)

The possible interference of neighbouring allergic patch-test reactions is still an open question. In this study, we investigated whether there is a distance-related mutual modification of neighbouring allergic patch-test reactions to nickel sulfate and potassium dichromate. We used a double-blind multicentre study design with randomized attachment of special TRUE Tests with 1, 3 and 7 cm distance between nickel sulfate and potassium dichromate patches. 589 patients with a history of nickel allergy (523 female, 66 male) were tested, with a mean age of 35 years. A log-linear modelling approach was used for statistical assessment of the relation between the distance separating neighbouring patch tests with nickel and dichromate and the reactions to the allergens. Non-reproducibility coefficients were compared by the generalized version of Fisher's exact test for arbitrary 2-dimensional contingency tables. For the left side of the back, virtually no differences (p=0.70) were found in the reaction patterns obtained for the 3 distances separating nickel and dichromate patch tests. On the right side of the back, the number of reactions to dichromate patches with only 1 cm distance from moderate/strong nickel reactions was lower than the number of positive dichromate tests at larger distances from nickel tests (on the border of statistical significance: p= 0.05). Corresponding side-related results were obtained for subgroups of patients with and without a history of atopic dermatitis. The non-reproducibility of reactions to dichromate was not significantly related to the distance between neighbouring tests. Our data argue against a "spillover" effect of strong/moderate nickel reactions, but indicate that such reactions may, under certain conditions, attenuate adjacent reactions to an unrelated allergen. In the case of future verification, this will have implications for the interpretation of patch tests.
Tear Film–Oriented Diagnosis and Tear Film–Oriented Therapy for Dry Eye Based on Tear Film Dynamics (2018)

In December 2010 and January 2012, 3% diquafosol sodium ophthalmic solution and 2% rebamipide ophthalmic suspension, respectively, appeared first in Japan as prescription drugs for the treatment of dry eye (DE). Since then, not only the diagnosis and treatment but also the understanding of the pathophysiology of DE have greatly advanced, and a new concept of layer-by-layer diagnosis and treatment for DE, respectively termed "tear-film-oriented diagnosis" (TFOD) and "tear-film-oriented therapy" (TFOT) was born. This new concept is currently in the process of expanding from Japan to other Asian countries. TFOD is the method used for the differential diagnosis of DE, which includes aqueous-deficiency DE (ADDE), decreased wettability DE (DWDE), and increased evaporation DE (IEDE), through the dynamics of tear film (TF) and breakup patterns (BUPs) after the eye is opened. BUPs and/or each diagnosed DE subtype are/is able to distinguish the insufficient components of the ocular surface that are responsible for each BUP in a layer-by-layer fashion. Aqueous fluid, membrane-associated mucins (especially MUC16), and the lipid layer and/or secretory mucins must be insufficient in ADDE, DWDE, and IEDE, respectively, and this allows for a layer-by-layer treatment to be proposed for each BUP via the supplementation of the insufficient components, using the topical therapy currently available. In Japan, TF breakup is regarded as a visible core mechanism for DE, and an abnormal breakup time (i.e., ≤5 seconds) and symptoms are currently used for the diagnosis of DE. Therefore, TFOD and TFOT could be an ideal and practical pathway for clinicians to manage DE.
A biomimetic vision-based hovercraft accounts for bees’ complex behaviour in various corridors (2014)

Here we present the first systematic comparison between the visual guidance behaviour of a biomimetic robot and those of honeybees flying in similar environments. We built a miniature hovercraft which can travel safely along corridors with various configurations. For the first time, we implemented on a real physical robot the 'lateral optic flow regulation autopilot', which we previously studied computer simulations. This autopilot inspired by the results of experiments on various species of hymenoptera consists of two intertwined feedback loops, the speed and lateral control loops, each of which has its own optic flow (OF) set-point. A heading-lock system makes the robot move straight ahead as fast as 69 cm s(-1) with a clearance from one wall as small as 31 cm, giving an unusually high translational OF value (125° s(-1)). Our biomimetic robot was found to navigate safely along straight, tapered and bent corridors, and to react appropriately to perturbations such as the lack of texture on one wall, the presence of a tapering or non-stationary section of the corridor and even a sloping terrain equivalent to a wind disturbance. The front end of the visual system consists of only two local motion sensors (LMS), one on each side. This minimalistic visual system measuring the lateral OF suffices to control both the robot's forward speed and its clearance from the walls without ever measuring any speeds or distances. We added two additional LMSs oriented at +/-45° to improve the robot's performances in stiffly tapered corridors. The simple control system accounts for worker bees' ability to navigate safely in six challenging environments: straight corridors, single walls, tapered corridors, straight corridors with part of one wall moving or missing, as well as in the presence of wind.
Longitudinal Changes in Hurricane Hazard Perception (1990)

Hurricane hazard perception data, periodically collected over a twelve year period from the same sample of Lower Florida Keys residents, were analyzed to determine what changes in hazard perception and mitigation behavior had occurred. Contrary to hypotheses that hazard concerns decline with length of residence in hazard zones, overall perceptions that both hurricane winds and flooding are problems facing local residents have increased. Awareness of the hurricane threat remains high, with two-thirds of the residents stating that it is likely that the area will experience a damaging hurricane within the next ten years, even though a major hurricane has not occurred within the area for nearly three decades.
Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 and -2 in Type 2 Diabetes (2004)

Cardiovascular risk reduction therapy in diabetic patients reduces vascular events (1) by retarding atherosclerosis and improving vascular reactivity. Matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) are integral to the vascular changes of atheroma, and MMP-9 and TIMP-1 are raised in diabetes (2). We hypothesized that global risk reduction of intensified diabetes and cardiovascular risk management in type 2 diabetes would be associated with reductions in circulating markers of extracellular matrix turnover, namely MMP-9, TIMP-1, and TIMP-2.

### Cross-sectional study

Eighty-six patients with type 2 diabetes (3) and treated hypertension with serum creatinine <120 mmol/l were recruited from local clinics (Table 1). Of these, 46% ( n = 36) had a clinical history of cardiovascular disease. Data from these patients were compared with 49 healthy control subjects. Ethical approval and informed consent were obtained.

### Interventional study

Sixty-five of the recruited diabetic patients (of whom 36 had cardiovascular disease) consented to intensified diabetes and cardiovascular risk management therapy. This consisted of 3 monthly consultations, lifestyle advice, and adjusting oral hypoglycemia therapy to achieve HbA 1c 25 kg/m 2 or added second-line in lean patients, who received initial treatment with gliclazide MR (30 mg o.d.) and vice versa. Insulin could be started if HbA 1c remained >7.0% despite …
Searching with numbers (2003)

A large fraction of the useful Web is comprised of specification documents that largely consist of (attribute name, numeric value) pairs embedded in text. Examples include product information, classified advertisements, resumes, etc. The approach taken in the past to search these documents by first establishing correspondences between values and their names has achieved limited success because of the difficulty of extracting this information from free text. We propose a new approach that does not require this correspondence to be accurately established. Provided the data has "low reflectivity", we can do effective search even if the values in the data have not been assigned attribute names and the user has omitted attribute names in the query. We give algorithms and indexing structures for implementing the search. We also show how hints (i.e., imprecise, partial correspondences) from automatic data extraction techniques can be incorporated into our approach for better accuracy on high reflectivity data sets. Finally, we validate our approach by showing that we get high precision in our answers on real data sets from a variety of domains.
zoo: S3 Infrastructure for Regular and Irregular Time Series (2005)

zoo is an R package providing an S3 class with methods for indexed totally ordered observations, such as discrete irregular time series. Its key design goals are independence of a particular index/time/date class and consistency with base R and the "ts" class for regular time series. This paper describes how these are achieved within zoo and provides several illustrations of the available methods for "zoo" objects which include plotting, merging and binding, several mathematical operations, extracting and replacing data and index, coercion and NA handling. A subclass "zooreg" embeds regular time series into the "zoo" framework and thus bridges the gap between regular and irregular time series classes in R.
Complexity-reduced digital predistortion for subcarrier multiplexed radio over fiber systems transmitting sparse multi-band RF signals (2013)

A novel multi-band digital predistortion (DPD) technique is proposed to linearize the subcarrier multiplexed radio-over-fiber (SCM-RoF) system transmitting sparse multi-band RF signal with large blank spectra between the constituent RF bands. DPD performs on the baseband signal of each individual RF band before up-conversion and RF combination. By disregarding the blank spectra, the processing bandwidth of the proposed DPD technique is greatly reduced, which is only determined by the baseband signal bandwidth of each individual RF band, rather than the entire bandwidth of the combined multi-band RF signal. Experimental demonstration is performed in a directly modulated SCM-RoF system transmitting two 64QAM modulated OFDM signals on 2.4GHz band and 3.6GHz band. Results show that the adjacent channel power (ACP) is suppressed by 15dB leading to significant improvement of the EVM performances of the signals on both of the two bands.
Biomedical Sensing with Free-Standing Complementary Supercell Terahertz Metasurfaces (2020)

We present a free-standing terahertz metasurface supercell that consists of four complementary mirrored asymmetric split-rectangular resonators. The quality factor of the excited resonance of this supercell has been significantly improved by 250% when compared to its counterpart nonmirrored supercell. The mirroring of the resonators leads to an enhanced out-of-phase oscillating current in each neighboring resonators of the supercell. In turn, this leads to a suppression of the dipole moments and its corresponding scattered fields. Moreover, this design can be realized by utilizing a simple laser machining technique. Furthermore, we numerically evaluate the performance of this design as a label-free biosensor for thin-film analytes and biomolecules such as double-stranded DNA and single-stranded RNA viruses. A sensitivity level of 1.14 × 105 nm/refractive index unit (RIU) can be achieved using this design. Therefore, this design has the potential to be used as an effective label-free biomedical sensor for in-situ detection of various biomolecules.