gebhart/patrepeval huggingface dataset:
Hemodynamic Tandem Intracranial Lesions on Magnetic Resonance Angiography in Patients Undergoing Carotid Endarterectomy (2016)

In patients undergoing carotid endarterectomy, a significant number of preoperative TILs demonstrated hemodynamic components, which were reversed postoperatively. The presence of such components was distinctively associated with the postoperative incidence of new ischemic lesions.
Multi-region and single-cell sequencing reveal variable genomic heterogeneity in rectal cancer (2017)

Our results suggest each tumor possesses its own architecture, which may result in different diagnosis, prognosis, and drug responses. Remarkable ITH exists in the two patients we have studied, providing a preliminary impression of ITH in rectal cancer.
MARKET DECISION MAKING FOR ONLINE AUCTION SELLERS: PROFIT MAXIMIZATION OR SOCIALIZATION (2006)

The purpose of this investigation is to identify factors in the decision making processes used by online auction sellers to select their online auction sales channel. Examining these decision factors will aid in creating a model of online auction seller channel evaluation mechanisms including economic and social factors and may be used by online auction services and intermediaries to maximize their market potential by increasing the perceived value of the various economic or social factors influencing seller outlet selection. An exploratory survey analysis is used to identify the components that online seller’s use for online channel selection.
How Artificial Intelligence and Machine Learning Will Change Content Creation Methodologies (2017)

For almost 30 years, Digital Nonlinear Editing Systems (DNLEs) have functioned as a practical replacement for film and videotape editing. While DNLEs have progressed in their capabilities by offering increased video resolutions and visual effects, they have not fundamentally changed their operational constructs. Editors must still choose in and out points of shots and then methodically edit those shots into a cohesive sequencing. — Technology improvements in Artificial Intelligence (AI) and Machine Learning (ML) have the potential to profoundly impact how DNLE systems operate and, in turn, content creation methodologies will dramatically change. This paper will examine the effects of image recognition, natural speech processing, language recognition, cognitive metadata extraction, tonal analysis, and data and statistical integration on the creation of content.
Avelumab in Patients With Metastatic Colorectal Cancer (2023)

As demonstrated with other anti-PD-1/PD-L1 monoclonal antibodies, avelumab is not active in unselected patients with mCRC (ClinicalTrials.gov Identifier: NCT01772004).
Superiority of [68Ga]-DOTATATE PET/CT to Other Functional Imaging Modalities in the Localization of SDHB -Associated Metastatic Pheochromocytoma and Paraganglioma (2015)

[(68)Ga]-DOTATATE PET/CT showed a significantly superior detection rate to all other functional and anatomical imaging modalities and may represent the preferred future imaging modality in the evaluation of SDHB-related metastatic PHEO/PGL.
A NARROWBAND, CRYSTAL CONTROLLED BIOMEDICAL TELEMETRY SYSTEM (1972)

International Telemetering Conference Proceedings / October 10-12, 1972 / International Hotel, Los Angeles, California
Adaptive resistance to lorlatinib via EGFR signaling in ALK-rearranged lung cancer (2023)

Anaplastic lymphoma kinase (ALK)-tyrosine kinase inhibitors rarely elicit complete responses in patients with advanced ALK-rearranged non-small cell lung cancer (NSCLC), as a small population of tumor cells survives due to adaptive resistance. Therefore, we focused on the mechanisms underlying adaptive resistance to lorlatinib and therapeutic strategies required to overcome them. We found that epidermal growth factor receptor (EGFR) signaling was involved in the adaptive resistance to lorlatinib in ALK-rearranged NSCLC, activation of which was induced by heparin-binding EGF-like growth factor production via c-Jun activation. EGFR inhibition halted ALK-rearranged lung cancer cell proliferation by enhancing ALK inhibition-induced apoptosis via suppression of Bcl-xL. Xenograft models showed that the combination of EGFR inhibitor and lorlatinib considerably suppressed tumor regrowth following cessation of these treatments. This study provides new insights regarding tumor evolution due to EGFR signaling after lorlatinib treatment and the development of combined therapeutic strategies for ALK-rearranged lung cancer.
Extracting key phrases to disambiguate personal name queries in web search (2006)

Assume that you are looking for information about a particular person. A search engine returns many pages for that person's name. Some of these pages may be on other people with the same name. One method to reduce the ambiguity in the query and filter out the irrelevant pages, is by adding a phrase that uniquely identifies the person we are interested in from his/her namesakes. We propose an unsupervised algorithm that extracts such phrases from the Web. We represent each document by a term-entity model and cluster the documents using a contextual similarity metric. We evaluate the algorithm on a dataset of ambiguous names. Our method outperforms baselines, achieving over 80% accuracy and significantly reduces the ambiguity in a web search task.
The razorback CCD: A high-performance parallel input delay line architecture (1975)

An analog CCD delay line with multiple input taps which can be used singly to provide a selectable bit delay, or in parallel to perform delay-sum and multiplexing signal operations, will be covered. These taps are realized along the delay line with high transfer efficiency and large bandwidth.
Active network based management for QoS assured multicast delivered media (2002)

In this paper, we address the application specific management and monitoring of highly dynamic services. The target service is the multicasting of video streams to residential users over an ATM/ADSL access network. The high dynamicity is given by the frequent channel change operation performed in parallel by thousands of users. We approach the monitoring issue using the active network based paradigm, where code is dynamically deployed and executed in the network.
Evaluation of antimicrobial potential of some Indian medicinal plants against some pathogenic microbes (2011)

The aim of the study was to evaluate the antimicrobial property of five medicinal plants, viz. Ocimum basilicum Linn., Peltophorum ferrugineum (Decne) Benth., Phyllanthus fraternus Webster, Triumfetta rotundifolia Lam. and Ziziphus nummularia (Burm.f.) Wight & Arn. found in India. The plants were extracted using cold percolation method with different solvents (petroleum ether, acetone and methanol) against four Gram positive bacteria, four Gram negative bacteria and two fungi by agar well diffusion method. Micrococcus flavus and Proteus vulgaris were the most susceptible bacteria and Candida tropicalis was the most susceptible fungi among the screened microorganisms. Amongst the plants screened, P. ferrugineum showed best antibacterial activity in both acetone and methanol extracts.
Etude de nouveaux systèmes amorceurs photo/thermiques à base d'Aldéhydes pour la polymérisation sous air (2010)

Le sujet de la these a ete oriente vers trois axes majeurs : l'etude de la photochimie des aldehydes et de leur capacite a photoamorcer une polymerisation radicalaire, l'etude des aldehydes en tant qu'amorceurs thermiques, avec l'etude des interactions entre des aldehydes et des sels metalliques ou des sels d'iodonium et le developpement industriel de formulations (ex: peinture) reticulables via les systemes photochimique et/ou thermique developpe avec des aldehydes.Les aldehydes sont des photoamorceurs efficaces sous irradiation UV-B. De nombreux aldehydes, notamment les aromatiques, sont meilleurs sous air grâce au cycle de photo-oxydation. Le mecanisme general de la reaction a ete determine au cours de cette these. Les aldehydes sont egalement capables de sensibiliser les sels d'iodonium par transfert d'electron et/ou d'energie et/ou par FRPCP, et ainsi d'amorcer une polymerisation cationique. Tout au long de la these, de nombreuses applications industrielles ont vu le jour grâce a la recherche realisee sur les aldehydes et le systeme d'amorcage photo/thermique. Des applications ont egalement ete adaptees au nouveau systeme afin d'augmenter les performances du systeme amorceur precedent et d'en diminuer le cout.
New Broad-Spectrum Antibacterial Amphiphilic Aminoglycosides Active against Resistant Bacteria: From Neamine Derivatives to Smaller Neosamine Analogues (2016)

Aminoglycosides (AGs) constitute a major family of potent and broad-spectrum antibiotics disturbing protein synthesis through binding to the A site of 16S rRNA. Decades of widespread clinical use of AGs strongly reduced their clinical efficacy through the selection of resistant bacteria. Recently, conjugation of lipophilic groups to AGs generated a novel class of potent antibacterial amphiphilic aminoglycosides (AAGs) with significant improved activities against various sensitive and resistant bacterial strains. We have identified amphiphilic 3',6-dialkyl derivatives of the small aminoglycoside neamine as broad spectrum antibacterial agents targeting bacterial membranes. Here, we report on the synthesis and the activity against sensitive and resistant Gram-negative and/or Gram-positive bacteria of new amphiphilic 3',4'-dialkyl neamine derivatives and of their smaller analogues in the 6-aminoglucosamine (neosamine) series prepared from N-acetylglucosamine.
Expert Evaluation of Haptic Virtual Reality User Interfaces for Medical Landmarking (2022)

Three-dimensional (3D) models have widely been used in medical diagnosis and planning tasks. Haptic virtual reality (VR) interfaces implemented by using VR equipment and haptic devices have previously been proposed for these medical 3D manipulation tasks. They have been found to be faster and more accurate in a medical marking task with novel users, compared with the traditional 2D interaction technique that uses a mouse and a 2D display. In this study, we recruited medical experts who do the medical landmarking task as part of their daily work to examine the performance of haptic VR interfaces and to investigate experts’ user experience. There were no statistically significant differences between the haptic user interfaces and the mouse-based 2D interface in terms of task completion time and marking accuracy. Based on experts’ subjective data, haptic VR interfaces showed great potential for medical work because of the natural input methods and haptic feedback.
Registration evaluation of dynamic breast MR images (2005)

The interpretation of dynamic contrast-enhanced breast MR images is predicated on the assumption of minimal voxel movement during the time course of the image ac-quisition. Misalignment of the dynamic image sequence as a result of movement during image acquisition can lead to potentially misleading diagnostic conclusions. In this pa-per a new methodology is presented for assessing the de-gree of in-plane (intra-slice) movement in a dynamic image sequence. The method is demonstrated on data from six sub-jects. The conclusion is that the method makes it possible to quantitatively qualify the accuracy of computed enhance-ment curves and more importantly to identify unacceptably poor registration. 1.
Array privatization for parallel execution of loops (2014)

In recent experiments, array privatization played a critical role in successful parallelization of several real programs. This paper presents compiler algorithms for the program analysis for this transformation. The paper also addresses issues in the implementation.
An Interview with Dr. Charu Aggarwal, Winner of ACM SIGKDD 2022 Service Award (2022)

In recognition of outstanding professional services and contributions to the field of knowledge discovery and data mining, Charu Aggarwal, Ph.D. is the recipient of the 2022 ACM SIGKDD Service Award. Conferred annually on an individual or group, Dr. Aggarwal was honored for his years of service and many contributions that span publishing, programming, sponsorship and more in support of SIGKDD. Dr. Aggarwal is Distinguished Research Staff Member at IBM T. J. Watson Research Center and was the recipient of the 2019 SIGKDD Innovation Award. He sat down with SIGKDD Explorations to discuss how he first became involved with the KDD conference, the evolution of his volunteerism, the focus of his work at IBM, and his advice to those early in their careers.
Comparative Study between Equivalent Circuit and Recurrent Neural Network Battery Voltage Models (2021)

&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;Lithium-ion battery (LIB) terminal voltage models are investigated using two modelling approaches. The first model is a third-order Thevenin equivalent circuit model (ECM), which consists of an open-circuit voltage in series with a nonlinear resistance and three parallel RC pairs. The parameters of the ECM are obtained by fitting the model to hybrid pulse power characterization (HPPC) test data. The parametrization of the ECM is performed through quadratic-based programming. The second is a novel modelling approach based on long short-term memory (LSTM) recurrent neural networks to estimate the battery terminal voltage. The LSTM is trained on multiple vehicle drive cycles at six different temperatures, including −20°C, without the necessity of battery characterization tests. The performance of both models is evaluated with four automotive drive cycles at each temperature. The results show that both models achieve acceptable performance at all temperatures. However, the LSTM performs better in 92% of the cases, especially at lower temperatures, where it has as much as two-thirds lower error than the ECM approach.&lt;/div&gt;&lt;/div&gt;
Vein to Artery Grafts (1981)

Iliolumbar vein to iliac artery grafts were placed in 40 rats by microsurgical technique. Groups of animals were perfused with fixative at eight intervals between one and 20 weeks after operation, and sections of the graft and control arteries (the opposite iliacs) were analyzed microscopically. The revascularization of the graft by capillaries commenced within the first postoperative week. The level of vascularity (capillaries per cross-sectional mm2) increased during the first four weeks, maintained a constant level and declined after week 16. The grafts of the 17--20 week group were substantially less vascular than the earlier groups. Intimal thickening commenced at three to four weeks after operation, i.e. during the period of increasing graft vascularity. The mean intimal proportion of the graft was 14% at four to five weeks and at 17--20 weeks was 35% of the cross-sectional area of the graft wall. However, the actual thickness of the intima did not increase significantly with time, rather the whole graft wall tended to become thinner. At 17--20 weeks grafts which showed a high degree of intimal thickening had significantly fewer capillaries within their walls. Quantitative evidence is presented to suggest that the continued growth of the graft intima may not be supported by a similar increase in the number of vasa vasorum. Therefore, it is suggested that the reduced level of vascularity in grafts with hyperplastic intimae may form an ischemic basis for degenerative changes which are known to take place in some long-term grafts.
Functional and morphological evaluation of a low‐weight, monofilament polypropylene mesh for hernia repair (2002)

With more than 1 million implantations per year worldwide, mesh repair has become a standard procedure for the treatment of hernias. Apart from various technical problems, the type of material has been proven to be of considerable importance for the functional and histological outcome, particularly for long-term implantation. Whereas the advantageous application of low-weight, large-pore meshes based on multifilaments can be stated without doubt, it is still open whether similar results can be achieved on the basis of pure monofilaments. In the present study, a low-weight polypropylene mesh (LW) made purely of monofilaments was compared to a common heavy-weight polypropylene mesh (HW) in regard to the functional consequences and the tissue response. After implantation in rats as an inlay for 3--90 days, the abdominal-wall mobility of the implant region was recorded by 3D stereography, and the tensile strength of both the suture zone and the mesh was measured. The morphometry of the histological reaction in regard to the inflammatory infiltrate, the connective tissue, the number of granulocytes, macrophages, and fibroblasts served to reflect the tissue response. As parameters for the remodeling process at the interface the cellular activation was evaluated by TUNEL (DNA-strand breaks or apoptosis, respectively), Ki 67 (cell proliferation), and HSP 70 (cell stress). The measured tensile strength of the LW mesh confirmed a sufficient strength of the material-reduced mesh modification. After implantation the consecutive impairment of the abdominal-wall mobility was reduced compared to the HW mesh, concomitant to the reduced fibrotic level at the interface. At the end of the observation period the foreign-body reaction was significantly lowered for the LW mesh, almost reaching physiological values. In conclusion, these data confirm the improved biocompatibility of material-reduced mesh implants.
Structural and molecular analysis of a protective epitope of Lyme disease antigen OspA and antibody interactions (2016)

The murine monoclonal antibody LA-2 recognizes a clinically protective epitope on outer surface protein (OspA) of Borrelia burgdorferi, the causative agent of Lyme disease in North America. Human antibody equivalence to LA-2 is the best serologic correlate of protective antibody responses following OspA vaccination. Understanding the structural and functional basis of the LA-2 protective epitope is important for developing OspA-based vaccines and discovering prophylactic antibodies against Lyme disease. Here, we present a detailed structure-based analysis of the LA-2/OspA interaction interface and identification of residues mediating antibody recognition. Mutations were introduced into both OspA and LA-2 on the basis of computational predictions on the crystal structure of the complex and experimentally tested for in vitro binding and borreliacidal activity. We find that Y32 and H49 on the LA-2 light chain, N52 on the LA-2 heavy chain and residues A208, N228 and N251 on OspA were the key constituents of OspA/LA-2 interface. These results reveal specific residues that may be exploited to modulate recognition of the protective epitope of OspA and have implications for developing prophylactic passive antibodies.
Coordinated distributed moving horizon state estimation for linear systems based on prediction‐driven method (2017)

The distributed framework has been considered as one promising framework for the control of large‐scale systems. In this work, we propose a coordination algorithm for distributed moving horizon state estimators (MHEs) for discrete‐time linear systems composed of subsystems. In particular, the class of linear system we focus on is composed of several subsystems that interact with each other via their states. In the proposed coordinated distributed MHE (CDMHE) scheme, each subsystem is associated with a local MHE. In the design of a local MHE, a coordinating term is incorporated into its cost function which is determined by an upper‐layer coordinator. At each sampling time, a local MHE estimates its local state and system noise, and then sends them to the coordinator. The coordinator calculates a price vector based on information received from all the local MHEs and sends the price vector together with the calculated interaction estimates to each local MHE. The above steps are performed iteratively every sampling time. It is shown that the CDMHE scheme is able to achieve the estimation performance of the corresponding centralized design if convergence at each sampling time is ensured. A simulation study based on a chemical process is presented to illustrate the applicability and effectiveness of the proposed scheme. The cases with communication failures, and premature termination are also discussed.
ChemInform Abstract: Crystal Structure and Physical Properties of Ce3Pd6Sb5. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
P-ADRIP : un système multi-agent auto-organisateur pour la prévision du trafic routier (2022)

Evènement affilié à PFIA 2022
Nonlinear coupling of low n modes in PBX-M (1994)

In many of the medium and high beta discharges in PBX-M, low n modes (n=1-4) with different n numbers are observed. The prevalence of low n modes decreases with increasing n number. Furthermore, if two modes of different frequency and n number (ω1, and ω2; k1 and k2) are simultaneously present in the plasma, these modes interact non-linearly and create sidebands in frequency (ω2 ± ω1) and wavenumber (k2 ± k1 or n2 ± n1 and m2 ± m1). It has also been observed that if these fundamental modes, ω1/k1 and ω2/k2, contain strong harmonics, the harmonics also interact non-linearly, creating more non-linear products: kω2 ± lω1 and kk2 ± lk1, where k and l are integers describing the harmonics. These multiple three wave couplings on a given rational surface can create several modes of the same m and n numbers but of different phase velocities. The multiple perturbations of the rational surfaces can increase the plasma losses. In fact, a decrease in neutron rate and an enhanced loss of medium energy ions are observed during this three wave coupling interaction. Although the three wave coupling has been observed primarily in medium or high beta discharges, it is a more general plasma phenomenon because it also occurs occasionally at low β
Relationship of Field versus Laboratory Compaction to Hot- and Warm-Mixed Asphalt Rutting Performance (2021)

Rutting is a major distress for asphalt pavements. This paper examines the relationship of laboratory- and field-compaction methods to rutting performance based on aggregate packing characteristics. Four hot- and warm-mixed asphalts were produced and placed at full scale in test sections. Accelerated pavement testing (APT) to simulate military aircraft was utilized to assess mixture rutting performance. Cores from the test sections were used for laboratory testing. A plant-produced mixture was used for laboratory compaction of test specimens. Laboratory rut testing was conducted with the Asphalt Pavement Analyzer utilizing unique test conditions and with the Hamburg loaded wheel tracker under standard test conditions. Results indicated a large difference in performance between field- and laboratory-compacted test specimens: laboratory specimens performed much better than field-compacted ones. Aggregate microstructure analysis was performed for both field- and laboratory-compacted material using asphalt mixture imaging analysis software. Results indicated a large difference in aggregate packing as measured by total proximity zone length. The difference in aggregate packing was independent of bulk volumetric properties but had a large effect on mixture rutting performance.