gebhart/patrepeval huggingface dataset:
Digital Oil Model Development and Verification (2021)

Abstract Advances in digital technologies have the potential to enhance model predictive capability and redefine its boundaries at various scale. Digital oil with accurate representation of atomistic components is a powerful tool to analyze both macroscopic properties and microscopic phenomena of crude oil under any thermodynamic conditions. Digital oil model presented in this paper is the key input in molecular chemistry modeling for designing chemical enhanced oil recovery formulation. Hence, it is constructed based on a fit-for purpose strategy focusing in oil components that have large contribution to microemulsion stability. Complete crude oil composition could comprise over 100,000 components. Lengthy simulation time is required to simulate all crude oil components which is impratical, despite the challenges to identify all crude oil components experimentally. Therefore, we established a practical experimental strategy to identify key crude oil components and constructed the digital oil model based on surrogate components. The surrogate components are representative molecules of the volatiles, saturates, aromatics and resins. Two-dimensional digital oil model, with aromaticity on one axis, and the size of the molecules on the other axis was constructed. We developed algorithm to integrate nuclear magnetic resonance response with architecture of the molecular structure. A group contribution method was implemented to ensure reliable representation of the molecular structure. We constructed the digital oil models for a field in Malaysia Basin. We validated the physical properties of the digital oil model with properties measured from experiment, predicted from molecular dynamics simulation and calculated from quantitative property-property relationship method. Good agreement was obtained from the validation, with less than 5% and 13% variance in crude density and Equivalent Alkane Carbon Number respectively, indicating that the molecular characteristic of the digital oil model was captured correctly. We adopted the digital oil model in molecular chemistry modeling to gain insights into microemulsion formation in chemical enhanced oil recovery formulation design. Digital oil is a robust tool to make predictions when information cannot be extracted from experimental data alone. It can be extended for engineering applications involving processing, safety, hazard, and environmental considerations.
A peptide corresponding to the N‐terminal 13 residues of T4 lysozyme forms an α‐helix (1993)

Solid-phase methods have been used to synthesize LYS(1-13), a peptide corresponding to the first 13 residues of T4 lysozyme. 2D 1H NMR techniques were used to investigate its solution structure in the presence of SDS micelles. The identification of numerous medium-range NOESY crosspeaks and several slowly exchanging NH protons indicated the presence of an alpha-helical structure. This was confirmed by simulated annealing calculations performed using XPLOR.
Distributed Task Allocation for Visual Sensor Networks: A Market-Based Approach (2010)

This work in progress presents a novel distributed task allocation method for visual sensor networks based on a computational market. Our proposed method automatically adapts the QoS levels of the individual tasks, depending on the resource requirements and the user-defined interest level of the service. Therefore, we define virtual commodity markets, where decentralized producer agents sell resource shares of nodes and communication links. Producer agents adapt their unit prices for resources depending on the demand for the individual resources. In this paper we discuss two pricing models: adjusted linear pricing and rate adaptive pricing. To allocate resources required for executing a task, a task allocation agent requests a number of offers from different producer agents. Task allocation agents use the received interest levels, which correspond to the virtual money, to lease resource shares for a specific time.
Comparison of single dose netilmicin with a five-day course of co-trimoxazole for uncomplicated urinary tract infections. (1984)

Women with uncomplicated urinary tract infections were randomly allocated to either a single 150 mg intramuscular dose of netilmicin or a standard five-day course of oral co-trimoxazole. Twenty-one of 22 were cured with netilmicin and all 20 with co-trimoxazole. No patient treated with netilmicin developed any side effects or obvious toxicity. Following co-trimoxazole one woman developed a severe skin rash and another nausea. Netilmicin is another drug which is highly effective when used in a single dose regimen for the treatment of uncomplicated urinary tract infections. There are many advantages of this approach to the management of a common clinical problem.
BMP-2 Dose-Response and Release Studies in Functionally Graded HAp (2006)

Hydroxyapatite (HAp) has been used as a biomaterial for hard tissues. Critical characteristics of biomaterials will include surface geometry, hydrophobicity and hydrophilicity, crystallinity, biodegradation rates, and release pharmacokinetics (PK) of incorporated molecules such as BMP-2. Optimizing BMP-2 for clinical application may be dependent on localized sustained release from biomaterials. We forcused on in vivo local BMP-2 PK and bone induction in two ceramics systems, based on different surface structures. The functionally graded apatites (fg-HAp) was designed by the step-wise calcinations and partial dissolution-precipitation methods. We estimated the in vivo release profile of 125I-labeled BMP-2 from fg-HAp and the dose response of bone induction by BMP-2 in the back subcutis histologically. Bulk-HAp (b-HAp) by only the step-wise calcinations was prepared as a control. The amount of BMP-2 remaining in the fg-HAp at 1 day after implantation was 83.8%, while that was 34.6% in the b-HAp. Moreover, ectopic bone formation were found surely in the fg-HAp/BMP-2 (0.5μg) system at 3 weeks, not in the b-HAp/BMP-2 system. By using fg-HAp, it is likely that an extremely low dose of BMP-2 is enough to enhance bone induction if BMP-2 is appropriately delivered to the site of action.
Pathology to define epidermal margin and depth of surgical debridement of diabetic foot ulcers (2008)

Balu Chandrasekaran, Eashwar MS; Golinko, Michael MD, MA; Vukelic, Sasa MD; Joffe, Renata MD; Stojanidovic, Olivera MD; Tomic-Canic, Marjana PhD; Brem, Harold MD, FACS Author Information
<i>myc2-322B</i> exhibits enhanced root JA responses in a NINJA-dependent manner. (2015)

&lt;p&gt;&lt;i&gt;JGP&lt;/i&gt; expression in 5-do seedlings of WT (A), &lt;i&gt;myc2-322B&lt;/i&gt; (B, &lt;i&gt;m2-322B&lt;/i&gt;) and &lt;i&gt;ninja-1 myc2-322B&lt;/i&gt; (C, &lt;i&gt;n-1 m2-322B&lt;/i&gt;). Note the constitutive reporter activity stained in blue (Scale bars = 0.5 mm). (D) qRT-PCR of basal &lt;i&gt;JAZ10&lt;/i&gt; expression in 5-do roots of &lt;i&gt;myc2-322B&lt;/i&gt;, &lt;i&gt;ninja-1&lt;/i&gt; (&lt;i&gt;n-1&lt;/i&gt;), &lt;i&gt;ninja-1 myc2-322B&lt;/i&gt; (&lt;i&gt;n-1 m2-322B&lt;/i&gt;), &lt;i&gt;ninja-2 myc2-322B&lt;/i&gt; (&lt;i&gt;n-2 m2-322B&lt;/i&gt;), &lt;i&gt;ninja-1 myc2-322B/+&lt;/i&gt; (&lt;i&gt;n-1 m2-322B/+&lt;/i&gt;) and &lt;i&gt;ninja-2 myc2-322B/+&lt;/i&gt; (&lt;i&gt;n-2 m2-322B/+&lt;/i&gt;). &lt;i&gt;JAZ10&lt;/i&gt; transcript levels were normalized to those of &lt;i&gt;UBC21&lt;/i&gt; and displayed relative to the expression of unwounded WT samples, which are set to 1. Bars represent the means of three biological replicates (±SD), each containing a pool of ~60 roots. Complete qRT-PCR data are in &lt;a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1005300#pgen.1005300.s027" target="_blank"&gt;S1 File&lt;/a&gt;. (E) Root length quantification of WT and 7-do mutant lines. Data are the means (±SD) from 20–48 plants. Primary root meristem cell number (F) and box plot summary of cortex-cell length (G) in 5-do seedlings of WT and mutant lines grown in control conditions, and of WT grown in presence of 25 μM MeJA (n = 10). Letters above bars and box plots (E-G) indicate statistically significant differences between samples as determined by Tukey’s HSD tests (P &lt; 0.01).&lt;/p&gt;
Transfer of Pectobacterium chrysanthemi (Burkholder et al. 1953) Brenner et al. 1973 and Brenneria paradisiaca to the genus Dickeya gen. nov. as Dickeya chrysanthemi comb. nov. and Dickeya paradisiaca comb. nov. and delineation of four novel species, Dickeya dadantii sp. nov., Dickeya dianthicola sp. nov., Dickeya dieffenbachiae sp. nov. and Dickeya zeae sp. nov. (2005)

A collection of 75 strains of Pectobacterium chrysanthemi (including all biovars and pathovars) and the type strains of Brenneria paradisiaca (CFBP 4178(T)) and Pectobacterium cypripedii (CFBP 3613(T)) were studied by DNA-DNA hybridization, numerical taxonomy of 121 phenotypic characteristics, serology and 16S rRNA gene-based phylogenetic analyses. From analysis of 16S rRNA gene sequences, it was deduced that P. chrysanthemi strains and B. paradisiaca CFBP 4178(T) formed a clade distinct from the genera Pectobacterium and Brenneria; therefore, it is proposed to transfer all the strains to a novel genus, Dickeya gen. nov. By DNA-DNA hybridization, the strains of P. chrysanthemi were distributed among six genomic species: genomospecies 1 harbouring 16 strains of biovar 3 and four strains of biovar 8, genomospecies 2 harbouring 16 strains of biovar 3, genomospecies 3 harbouring two strains of biovar 6 and five strains of biovar 5, genomospecies 4 harbouring five strains of biovar 2, genomospecies 5 harbouring six strains of biovar 1, four strains of biovar 7 and five strains of biovar 9 and genomospecies 6 harbouring five strains of biovar 4 and B. paradisiaca CFBP 4178(T). Two strains of biovar 3 remained unclustered. Biochemical criteria, deduced from a numerical taxonomic study of phenotypic characteristics, and serological reactions allowed discrimination of the strains belonging to the six genomic species. Thus, it is proposed that the strains clustered in these six genomic species be assigned to the species Dickeya zeae sp. nov. (type strain CFBP 2052(T)=NCPPB 2538(T)), Dickeya dadantii sp. nov. (type strain CFBP 1269(T)=NCPPB 898(T)), Dickeya chrysanthemi comb. nov. (subdivided into two biovars, bv. chrysanthemi and bv. parthenii), Dickeya dieffenbachiae sp. nov. (type strain CFBP 2051(T)=NCPPB 2976(T)), Dickeya dianthicola sp. nov. (type strain CFBP 1200(T)=NCPPB 453(T)) and Dickeya paradisiaca comb. nov., respectively.
Hybrid Finite-Element Method for Discretizing Cylindrically Symmetric Parts in Electrotechnical Models (2006)

When the geometry, the excitations and the boundary conditions of an electrotechnical model feature a transversal or cylindrical symmetry, the electromagnetic fields are known to preserve this symmetry. Then, the model is commonly discretized by a 2D cartesian or axisymmetric finite-element (FE) mesh respectively. In many models, however, only parts of the geometry are symmetric. Then, the electromagnetic fields are in general not symmetric and a full 3D model is required. In this paper, such partially symmetric model parts are discretized by a hybrid FE method in order to reduce the problem size and to improve the simulation efficiency.
Faculty Opinions recommendation of Genetic variants of CC chemokine genes in experimental autoimmune encephalomyelitis, multiple sclerosis and rheumatoid arthritis. (2010)

Multiple sclerosis (MS) is a complex disorder of the central nervous system, causing inflammation, demyelination and axonal damage. A limited number of genetic risk factors for MS have been identified, but the etiology of the disease remains largely unknown. For the identification of genes regulating neuroinflammation we used a rat model of MS, myelin oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis (EAE), and carried out a linkage analysis in an advanced intercross line (AIL). We thereby redefine the Eae18b locus to a 0.88 Mb region, including a cluster of chemokine genes. Further, we show differential expression of Ccl2, Ccl11 and Ccl11 during EAE in rat strains with opposite susceptibility to EAE, regulated by genotype in Eae18b. The human homologous genes were tested for association to MS in 3841 cases and 4046 controls from four Nordic countries. A haplotype in CCL2 and rs3136682 in CCL1 show a protective association to MS, whereas a haplotype in CCL13 is disease predisposing. In the HLA-DRB1* 15 positive subgroup, we also identified an association to a risk haplotype in CCL2, suggesting an influence from the human leukocyte antigen (HLA) locus. We further identified association to rheumatoid arthritis in CCL2, CCL8 and CCL13, indicating common regulatory mechanisms for complex diseases. PMID: 19865101
Comparison of Physical-Layer and Application-Layer Diversity for Video Streaming Over Wireless Rayleigh Fading Channels (2006)

In this paper, we compare the performance of the diversity approach at the application layer and that at the physical layer for H.264/AVC encoded streaming video transmission in a wireless system with two independent channels. The application layer diversity is achieved by using multiple description source coding, while the physical layer diversity is obtained by channel coding over the two channels. Numerical results show that PHY layer diversity always outperforms the application layer diversity.
A multistatic microwave radar sensor for short range anticollision warning (2000)

An adequate radar technology for the detection and localization of obstacles before, behind and on the sides of a moving car is of primary importance to realize on-board devices able to perform different tasks such as parking, stop and go, and pre-alarm of the frontal air-bags. In these situations, the radar must acquire the position of the obstacles located at short distances from the car. This acquisition must be carried out with high radial and angular resolution; the former needs large radio frequency bandwidth, the latter requires large antennas and this means that the investigation area of the radar is certainly in the near field of the antenna. It is for this reason that traditional anti-collision systems based on phase array antennas prove to be unsuited to perform these tasks in the short range. The solution that we are proposing is based on several independent microwave radar sensors with wide angle of view connected to a central processing unit able to define the position and the relative velocity of the nearest obstacles. This prototype works in the 13.4-14 GHz frequency range at low power (16 dBm cirp) in accordance with the ETSI and CEPT/ERC Recommendations and it has been realized with microstrip technology so that thanks to its reduced size each device can be embedded easily in a bumper.
Synthesizing Energy Consumption Data Using a Mixture Density Network Integrated with Long Short Term Memory (2019)

Smart cities comprise multiple critical infrastructures, two of which are the power grid and communication networks, backed by centralized data analytics and storage. To effectively model the interdependencies between these infrastructures and enable a greater understanding of how communities respond to and impact them, large amounts of varied, real-world data on residential and commercial consumer energy consumption, load patterns, and associated human behavioral impacts are required. The dissemination of such data to the research communities is, however, largely restricted because of security and privacy concerns. This paper creates an opportunity for the development and dissemination of synthetic energy consumption data which is inherently anonymous but holds similarities to the properties of real data. This paper explores a framework using mixture density network (MDN) model integrated with a multi-layered Long Short-Term Memory (LSTM) network which shows promise in this area of research. The model is trained using an initial sample recorded from residential smart meters in the state of Florida, and is used to generate fully synthetic energy consumption data. The synthesized data will be made publicly available for interested users.
A Fluid-Solid-Growth Solver for Cardiovascular Modeling (2023)

We implement full, three-dimensional constrained mixture theory for vascular growth and remodeling into a finite element fluid-structure interaction (FSI) solver. The resulting "fluid-solid-growth" (FSG) solver allows long term, patient-specific predictions of changing hemodynamics, vessel wall morphology, tissue composition, and material properties. This extension from short term (FSI) to long term (FSG) simulations increases clinical relevance by enabling mechanobioloigcally-dependent studies of disease progression in complex domains.
Management of the postoperative pediatric cardiac surgical patient (2011)

The practice of pediatric cardiac intensive care has evolved considerably over the last several years. These efforts are the result of a collaborative effort from all subspecialties involved in the care of pediatric patients with congenital heart disease. Discoveries and innovations that are representative of this effort include the extension of cerebral oximetry from the operating room into the critical care setting; mechanical circulatory devices designed for pediatric patients; and surgery in very low birth weight neonates. Advances such as these impact postoperative management and make the field of pediatric cardiac intensive care an exciting, demanding, and evolving discipline, necessitating the ongoing commitment of various disciplines to pursue a greater understanding of disease processes and how to best go about treating them.
Synthesis and Morphological Behavior of Silicon-Containing Triblock Copolymers for Nanostructure Applications (1998)

We report the synthesis of high molecular weight triblock copolymers of the type ABA and BAB, where A is polyisoprene (PI) and B is poly(pentamethyldisilylstyrene) (P(PMDSS)), respectively. The volume fraction of the minority component (PI) for the ABA copolymer was 0.33, while that for the BAB copolymer was 0.23. The synthesis procedure of the P(PMDSS) blocks corresponded to that of polystyrene (PS), and low polydispersity with targeted compositions were achieved. The morphology of the triblock copolymers was characterized by transmission electron microscopy (TEM) and digital Fourier transform patterns. From TEM and diffraction analysis, the ABA polymer exhibited the double gyroid cubic morphology, while the BAB polymer showed a P(PMDSS) spherical domain morphology. The double gyroid morphology is the first to be reported in a silicon-containing block copolymer and consists of two three-dimensionally continuous, interpenetrating but nonintersecting networks of PI in a matrix of P(PMDSS)). Preliminary oxidative studies using ozone or O2-RIE on the tricontinuous phase show that nanoporous structures can be generated.
Synthesis and antibacterial activity of some new fused chromenes (2007)

A new class of pyrano [3,4-c]chromene, benzo[c]chromene, chromeno[3,4-c]pyridine and chromeno[4,3-c]pyrazole has been prepared from 3-benzoyl-2H-chromen-2-one 1. Most of the chromene derivatives showed moderate to high antibacterial activity as compared to the starting material 1.
Circuit level technique for mitigating effects of NBTI for wide fan-in domino logic circuits using supply voltage tuning (2015)

Transistor ageing has been a major problem as far as nanometre technology is concerned which leads to performance degradation and reliability issues. Ageing in pMOS transistor takes place due to Negative bias temperature instability (NBTI) which is a major threat in reliability as Iscale down the transistor geometries aggressively in our quest for low power and high performance. Overcoming ageing effect requires additional power expense, which in turn aggravates the power and heating problem. I propose an adaptive supply voltage (ASV) scheme as an arguably power efficient approach for variation resilience since it attempts to allocate power resources only where the negative effect of ageing is strong. Upon implementing the proposed approach on a host of domino logic circuits which include Current comparison domino (CCD) Ihave mitigated the rise in delay problem by suitably allocating a supply voltage so that the delay specifications are continuously met even after a lifespan of 10 years of operation at the expense of very low power headroom. Simulations have been performed using the BSIM4v4.7 model & 32 nm predictive technology model in SILVACO EDA tool at a frequency of 2 GHz and nominal supply voltage of 0.9V. The proposed approach has been implemented on 32 bit & 64 bit OR gates and also on 32 bit comparator and the results have been noteworthy.
A connectionist model of path integration with and without a representation of distance to the starting point (1998)

Path integration (dead reckoning) is the process by which animals use self-generated movement information to continuously update a representation of their position relative to some starting point. This allows them to return to this point, even in the absence of exteroceptive positional information. Path integration is a bicoordinate process: Both distance and direction to (or from) the starting point have to be maintained in the representation. Recent theoretical work based on neurobiological observations seems to lead to the conclusion that, in rodents at least, path integration is map based, implying a geocentered (earthbound) coordinate system. The present paper discusses, as a word of caution, the opposite notion that path integration in an impoverished, single-coordinate egocentered (animal-bound) polar coordinate system could account for some rather puzzling behavioral data previously recorded on hamsters. This admittedly strange position hinges on observations made on connectionist models of path integration that were developed to simulate the homing behavior of hamsters.
Linearization stability results and active measurements for the Einstein-scalar field equations (2014)

We study the Einstein equations coupled with the scalar field equations, $\hbox{Ein}(g)=T$, $T=T(g,ϕ)+F^1$, and $\square_gϕ^\ell-m^2ϕ^\ell= F^2$, where the sources $F=(F^1, F^2)$ correspond to perturbations of the physical fields which we control. Here $ϕ=(ϕ^\ell)_{\ell=1}^L$ and $(M,g)$ is a 4-dimensional globally hyperbolic Lorentzian manifold. The sources $F$ need to be such that the fields $(g,ϕ,F)$ satisfy the conservation law $\hbox{div}_g(T)=0$. If $(g_ε,ϕ_ε)$ solves the above equations, $\dot g=\partial_εg_ε|_{ε=0}$, $\dotϕ=ϕ_ε|_{ε=0}$, and $f=(f^1,f^2)= \partial_εF_ε|_{ε=0}$ solve the linearized Einstein equations and the linearized conservation law $$ \frac 12 \hat g^{pk}\hat \nabla_p f^1_{kj}+ \sum_{\ell=1}^L f^2_\ell \, \partial_j\hatϕ_\ell=0, $$ where $\hat g= g_ε|_{ε=0}$ and $\hat ϕ= ϕ_ε|_{ε=0}$. Then $(\hat g,\hat ϕ)$ and $f$ have the linearization stability property. Here ask the converse: If $\dot g$, $\dot ϕ$, and $f$ solve the linearized Einstein equations and the linearized conservation law, are there $F_ε=(F^1_ε,F^2_ε)$ and $(g_ε,ϕ_ε)$ depending on $ε\in [0,ε_0)$, $ε_0&gt;0$, such that $(g_ε,ϕ_ε)$ solves the Einstein-scalar field equations and the conservation law. When $\hat g$ and $\hat ϕ$ vary enough and $L\geq 5$, we prove a microlocal version of this: When $Y\subset M$ is a 2-surface and $(y,η)\in N^*Y$, there is $f$ that is a conormal distibutions wrt. the surface $Y$ with a given principal symbol at $(y,η)$ such that $(\hat g,\hat ϕ)$ and $f$ have the linearization stability property.