gebhart/patrepeval huggingface dataset:
Electric Field Enhancement in 3-D Tapered Helix Antenna for Terahertz Applications (2014)

A tapered helix monopole as a part of a rectenna for the detection of terahertz radiation is proposed. The antenna consists of a truncated conical helix extruded from a planar spiral and in a nanometric metallic whisker connected to one of its edges. The whisker faces a semiconductor substrate constituting the antenna ground plane. The structure is designed to be combined with a rectifying junction, realized just below the whisker base, which produces the direct conversion of terahertz electromagnetic field into dc current. The figure of merit of the structure is the electric field enhancement factor at the metallic whisker/semiconductor interface. Numerical full-wave simulations show that, for the tapered helix monopole, the field enhancement factor value can be higher than 26 000, which is approximately one order of magnitude greater than previously reported values in the literature. Detailed description of the fabrication process and investigation of antenna performances for different values of geometrical parameters are presented.
Regionalism in the Canadian Community, 1867-1967: Canadian Historical Association, Centennial Seminars (1971)

Regionalism in the Canadian Community, 1867–1967: Canadian Historical Association, Centennial Seminars Get access Regionalism in the Canadian Community, 1867–1967: Canadian Historical Association, Centennial Seminars. Edited by Wade Mason. (Toronto: University of Toronto Press, 1969. x, 300 p. Illustrations, tables, index. $8.50.) Robert Hett Robert Hett University of Alberta Search for other works by this author on: Oxford Academic Google Scholar Western Historical Quarterly, Volume 2, Issue 2, April 1971, Pages 197–198, https://doi.org/10.2307/967756 Published: 01 April 1971
Optical lens-microneedle array for percutaneous light delivery (2016)

The limited penetration depth of light in skin tissues is a practical bottleneck in dermatologic applications of light-induced therapies, including anti-microbial blue light therapy and photodynamic skin cancer therapy. Here, we demonstrate a novel device, termed optical microneedle array (OMNA), for percutaneous light delivery. A prototype device with a 11 by 11 array of needles at a spacing of 1 mm and a length of 1.6 mm was fabricated by press-molding poly-(lactic acid) (PLA) polymers. The device also incorporates a matched microlens array that focuses the light through the needle tips at specific points to achieve an optimal intensity profile in the tissue. In experiments done with bovine tissues, the OMNA enabled us to deliver a total of 7.5% of the input photons at a wavelength of 491 nm, compared to only 0.85% without the device. This 9-fold enhancement of light delivery was close to the prediction of 10.8 dB by ray-tracing simulation and is expected to increase the effective treatment depth of anti-microbial blue light therapy significantly from 1.3 to 2.5 mm in human skin.
Estimating camera response functions using probabilistic intensity similarity (2008)

We propose a method for estimating camera response functions using a probabilistic intensity similarity measure. The similarity measure represents the likelihood of two intensity observations corresponding to the same scene radiance in the presence of noise. We show that the response function and the intensity similarity measure are strongly related. Our method requires several input images of a static scene taken from the same viewing position with fixed camera parameters. Noise causes pixel values at the same pixel coordinate to vary in these images, even though they measure the same scene radiance. We use these fluctuations to estimate the response function by maximizing the intensity similarity function for all pixels. Unlike prior noise-based estimation methods, our method requires only a small number of images, so it works with digital cameras as well as video cameras. Moreover, our method does not rely on any special image processing or statistical prior models. Real-world experiments using different cameras demonstrate the effectiveness of the technique.
Palliative care (continuing education credit). (1992)

Care of the dying patient provides one of the most challenging areas of nursing practice. An understanding of the skills, principles and range of palliative care can enable practitioners to maximise the quality of life of those with advanced cancer and other progressive illnesses.
Meropenem-vaborbactam: a critical positioning for the management of infections by Carbapenem-resistant Enterobacteriaceae (2022)

Coupling of meropenem with the cyclic boronate derivative varobactam enhances considerably the in vitro intrinsic activity of meropenem against isolates producing KPC (<i>Klebsiella pneumoniae-</i>producing carbapenemase). The drug has linear elimination and the ratio of the area under the curve of the free drug to the minimum inhibitory concentration is the main pharmacodynamics variable determining bacterial clearance. Meropenem-vaborbactam is currently approved for the management of complicated urinary tract infections including acute pyelonephritis, complicated intraabdominal infections, and hospital-acquired pneumonia including ventilator-associated pneumonia.
A Guideline for the Optimum Fin Width Considering Hot-Carrier and NBTI Degradation in MuGFETs (2011)

Considering both hot-carrier and negative-bias-temperature-instability (NBTI) degradations, a guideline for the optimum fin width in p-channel multiple-gate MOSFETs (p-MuGFETs) has been suggested. From the different dependences of the fin width on both hot-carrier and NBTI degradations in p-MuGFETs, the optimum fin width has been extracted empirically to maximize the device lifetime. The optimum fin width increases as the stress temperature increases. When the fin width is narrower than the optimum fin width, the device lifetime is dominantly determined by NBTI degradation. However, when the fin width is wider than the optimum fin width, the device lifetime is determined by hot-carrier degradation. Considering both hot-carrier and NBTI degradations, the tradeoff between fin width and fin number has been discussed.
Simba Survey Toward High-Mass Star Forming Regions in the Southern Hemisphere (2006)

We summarize the results of a 1.2-mm dust continuum emission survey toward 146 IRAS point-sources, selected from the CS(2-1) survey of Bronfman et al. (1996), thought to be associated with young massive stars. The survey, carried out using the SIMBA Bolometer at the SEST in La Silla, is sensitive to detection of cores of at least 40 solar masses at a typical distance of 5 kpc. Regions of ∼;15′×10′ were mapped with angular resolution of 24″ toward each IRAS source, detecting 1.2-mm emission in all observed regions. Half of the maps show the presence of two or more 1.2 mm sources. The 1.2-mm cores associated with the IRAS sources have typically radii of 0.4 pc, masses of 4×103 M ⊙, luminosities of 2 × 105 L ⊙ and temperatures of 32 K. We have detected, in a handful of regions, 1.2-mm sources with no counterparts in the IRAS and MSX surveys, which we suggest correspond to cold, massive starless cores.
Comparative Evaluation of Microbiota Engraftment Following Fecal Microbiota Transfer in Mice Models: Age, Kinetic and Microbial Status Matter (2019)

The intestinal microbiota and its functions are intricately interwoven with host physiology. Colonizing rodents with donor microbiota provides insights into host-microbiota interactions characterization and the understanding of disease physiopathology. However, a better assessment of inoculation methods and recipient mouse models is needed. Here, we compare the engraftment at short and long term of genetically obese mice microbiota in germ-free (GF) mice and juvenile and adult specific pathogen free (SPF) mice. We also tested the effects of initial microbiota depletion before microbiota transfer. In the present work, donor microbiota engraftment was better in juvenile SPF mice than in adult SPF mice. In juvenile mice, initial microbiota depletion using laxatives or antibiotics improved donor microbiota engraftment 9 weeks but not 3 weeks after microbiota transfer. Microbiota-depleted juvenile mice performed better than GF mice 3 weeks after the microbiota transfer. However, 9 weeks after transfer, colonized GF mice microbiota had the lowest Unifrac distance to the donor microbiota. Colonized GF mice were also characterized by a chronic alteration in intestinal absorptive function. With these collective results, we show that the use of juvenile mice subjected to initial microbiota depletion constitutes a valid alternative to GF mice in microbiota transfer studies.
TapirXLA: Embedding Fork-Join Parallelism into the XLA Compiler in TensorFlow Using Tapir (2019)

This work introduces TapirXLA, a replacement for TensorFlow's XLA compiler that embeds recursive fork-join parallelism into XLA's low-level representation of code. Machine-learning applications employ a variety of technologies to improve performance, including compiler technology. But compilers in machine-learning frameworks lack a deep understanding of parallelism, causing them to lose performance by missing optimizations on parallel computation. This work studies how Tapir, a compiler intermediate representation (IR) that embeds parallelism into a mainstream compiler IR, can be incorporated into a compiler for machine learning to remedy this problem. TapirXLA modifies the XLA compiler in TensorFlow to employ the Tapir/LLVM compiler to optimize low-level parallel computation. TapirXLA encodes the parallelism within high-level TensorFlow operations using Tapir's representation of fork-join parallelism. Furthermore, TapirXLA exposes to the compiler implementations of linear-algebra library routines whose parallel operations are encoded using Tapir's representation. We compared the performance of TensorFlow using TapirXLA against TensorFlow using an unmodified XLA compiler. On four neural-network benchmarks, TapirXLA speeds up the parallel running time of the network by a geometric-mean multiplicative factor of 30% to 100%, across four CPU architectures.
TLR9 is up-regulated in human and murine NASH: pivotal role in inflammatory recruitment and cell survival (2017)

Our novel clinical data and studies in overnutrition models, including those with diabetes and metabolic syndrome, clarify TLR9 as a pro-inflammatory trigger in NASH. This response is mediated via M1-macrophages and neutrophil chemotaxis.
Visual Linguistic Analysis of Political Discussions: Measuring Deliberative Quality (2015)

This article reports on a Digital Humanities research project which is concerned with the automated linguistic and visual analysis of political discourses with a particular focus on the concept of deliberative communication. According to the theory of deliberative communication as discussed within political science, political debates should be inclusive and stakeholders participating in these debates are required to justify their positions rationally and respectfully and should eventually defer to the better argument. The focus of the article is on the novel interactive visualizations that combine linguistic and statistical cues to analyze the deliberative quality of communication automatically. In particular, we quantify the degree of deliberation for four dimensions of communication: Participation, Respect, Argumentation and Justification, and Persuasiveness. Yet, these four dimensions have not been linked within a combined linguistic and visual framework, but each single dimension helps determining the degree of deliberation independently from each other. Since at its core, deliberation requires sustained and appropriate modes of communication, our main contribution is the automatic annotation and disambiguation of causal connectors and discourse particles.
Thermally Activated Delayed Fluorescence Emitters for Deep Blue Organic Light Emitting Diodes: A Review of Recent Advances (2018)

Organic light-emitting diodes offer attractive perspectives for the next generation display and lighting technologies. The potential is huge and the list of potential applications is almost endless. So far, blue emitters still suffer from noticeably inferior electroluminescence performances in terms of efficiency, lifespan, color quality, and charge injection/transport when compared to that of the other colors. Emitting materials matching the NTSC standard blue of coordinates (0.14, 0.08) are extremely rare and still constitutes the focus of numerous academic and industrial researches. In this context, we review herein the recent developments on highly emissive deep-blue thermally activated delayed fluorescence emitters that constitute the third-generation electroluminescent materials.
A flagellar sheath protein of Helicobacter pylori is identical to HpaA, a putative N-acetylneuraminyllactose-binding hemagglutinin, but is not an adhesin for AGS cells (1997)

The gene encoding a 29-kDa flagellar sheath protein was cloned and found to be similar to hpaA, reported to encode an N-acetylneuraminyllactose-binding fibrillar hemagglutinin (D. G. Evans, T. K. Karjalainen, D. J. Evans, Jr., D. Y. Graham, and C. H. Lee, J. Bacteriol. 175:674-683, 1993). The transcriptional start was mapped by primer extension from Helicobacter pylori mRNA, indicating an active consensus promoter at a location different from that suggested by Evans et al. Immunogold labelling of the flagellar sheath with a monoclonal antibody to HpaA was demonstrated in four strains, contrary to previous reports of a surface (D. G. Evans, T. K. Karjalainen, D. J. Evans, Jr., D. Y. Graham, and C. H. Lee, J. Bacteriol. 175:674-683, 1993) or a cytoplasmic (P. W. O'Toole, L. Janzon, P. Doig, J. Huang, M. Kostrzynska, and T. J. Trust, J. Bacteriol. 177:6049-6057, 1995) locale. Agglutination of erythrocytes and adherence to AGS cells by a delta hpaA mutant were no different from those of the parent strain, confirming a recent finding of O'Toole et al.
Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma (2022)

ABSTRACT Lymphocytes play a key role in immune surveillance of tumors, but our understanding of the spatial organization and physical interactions that facilitate lymphocyte anti-cancer functions is limited. Here, we used multiplexed imaging, quantitative spatial analysis, and machine learning to create high-definition maps of tumor-bearing lung tissues from a Kras/p53 (KP) mouse model and human resections. Networks of directly interacting lymphocytes (‘lymphonets’) emerge as a distinctive feature of the anti-cancer immune response. Lymphonets nucleate from small T-cell clusters and incorporate B cells with increasing size. CXCR3-mediated trafficking modulates lymphonet size and number, but neoantigen expression directs intratumoral localization. Lymphonets preferentially harbor TCF1+/PD1+ progenitor CD8 T cells involved in responses to immune checkpoint blockade (ICB). Upon treatment of mice with ICB therapy or a neoantigen-targeted vaccine, lymphonets retain progenitor and gain cytotoxic CD8 T-cell populations, likely via progenitor differentiation. These data show that lymphonets create a spatial environment supportive of CD8 T-cell anti-tumor responses.
MedB-1 model from Dynamic Mathematical Modeling of IL13-Induced Signaling in Hodgkin and Primary Mediastinal B-Cell Lymphoma Allows Prediction of Therapeutic Targets (2023)

MedB-1 model from Dynamic Mathematical Modeling of IL13-Induced Signaling in Hodgkin and Primary Mediastinal B-Cell Lymphoma Allows Prediction of Therapeutic Targets
Uptake of cadmium is diminished in transfected mouse NIH/3T3 cells enriched for metallothionein. (1992)

To determine the relationship between cellular uptake of cadmium and content of metallothionein, we measured uptake of 109Cd in cells that differed in content of metallothionein (MT). MT cells were derived from NIH/3T3 cells by transfection with a plasmid containing the genome of bovine papilloma virus and the mouse metallothionein-I gene, driven by the promotor for the glucose-regulated protein of 78 kDa. Control cells were similarly transfected with bovine papilloma virus-based plasmids with the gene for metallothionein inverted and thus separated from the promoter (TM), or deleted, along with the promoter (BPA). The number of copies of bovine papilloma virus-based plasmids was similar in MT, TM, and BPA cells, approximately 100 per cell. MT cells were more than 10 times more resistant to the lethal effect of cadmium than were the control cells. Synthesis of metallothionein was 15-fold greater in the MT cells than in the TM or BPA cells. The uptake of 109Cd by the cells enriched in metallothionein was 4-fold less than by the control cells. These data suggest that an increased content of metallothionein may protect some cells from the toxic effects of cadmium, in part, by diminishing uptake of the metal.
Simultaneous, common‐volume lidar observations and theoretical studies of correlations among Fe/Na layers and temperatures in the mesosphere and lower thermosphere at Boulder Table Mountain (40°N, 105°W), Colorado (2013)

Abstract Simultaneous and common‐volume observations of Fe density, Na density, and temperatures in the mesosphere and lower thermosphere were made for 12 nights with an Fe Boltzmann lidar and a Na Doppler lidar at the Table Mountain Lidar Facility (40.13°N, 105.24°W) near Boulder, Colorado, in August and September 2010. We derive the correlations among temporal variations of Fe/Na densities and temperatures, eliminating the covariance bias via computing the cross correlations between Fe (Na) density and Na (Fe) temperature perturbations. The Fe‐Na density correlation is positive below the Fe layer peak and above the Na peak where the Fe/Na density gradients have the same signs but becomes negative in between the Fe and Na peaks where the gradients are opposite. The large correlation between temperature and density fluctuations is positive on the layer bottomside but negative on the topside with the transitions occurring near the layer peaks. The relative Fe/Na variances reach minimum near the layer peaks but rapidly increase and exceed the relative temperature variance significantly toward edges. These observations can be largely reproduced by theoretically modeling the metal layer responses to the wave‐induced perturbations only through dynamic processes with a Gaussian stationary density distribution. These results suggest that the dynamic effects (mainly the vertical displacement) induced by gravity waves or tides dominate the observed short‐term density and temperature variations over a night. We explain the Fe/Na gradient difference observed at the bottomside via the chemical “shelf” around 80 km for reactive chemicals and the Fe/Na layer height difference.
CVD Diamond for Electronic Devices and Sensors (2009)

Series Preface. Preface. List of Contributors. Basic Properties, Defects and Impurities, Surface properties and Synthesis. 1 Basic Properties of Diamond: Phonon Spectra, Thermal Properties, Band Structure ( Gordon Davies ). 2 Transport Properties of Electrons and Holes in Diamond ( Jan Isberg ). 3 Point Defects, Impurities and Doping ( Alison Mainwood ). 4 Surface Conductivity of Diamond ( Lothar Ley ). 5 Recent Progress in the Understanding of CVD Growth of Diamond ( J.E. Butler, A. Cheesman and M. N. R. Ashfold ). 6 Heteroepitaxial Growth ( M. Schreck ). Radiation Sensors. 7 Detectors for UV and Far UV Radiation ( Alan T. Collins ). 8 Diamond Radiation Sensors for Radiotherapy ( Mara Bruzzi ). 9 Radiation Sensors for High Energy Physics Experiments ( H. Kagan and W. Trischuk ). 10 CVD-Diamond Detectors for Experiments with Hadrons, Nuclei, and Atoms ( E. Berdermann and M. Ciobanu ). 11 Neutron Detectors ( G. Verona-Rinati ). Active Electronic Devices. 12 High-Power Switching Devices ( Jan Isberg ). 13 H-Terminated Diamond Field-Effect Transistors ( Makoto Kasu ). 14 Doped Diamond Electron Devices ( E. Kohn and A. Denisenko ). 15 Optoelectronic Devices Using Homoepitaxial Diamond p - n and p - i - n Junctions ( Toshiharu Makino and Hiromitsu Kato ). Electrochemical and Biological Sensors. 16 Biofunctionalization of Diamond Surfaces: Fundamentals and Applications ( J. A. Garrido ). 17 Diamond Electrochemical Sensors ( John S. Foord ). Micro-Electro-Mechanical Systems. 18 CVD Diamond MEMS ( J. Kusterer and E. Kohn ). Superconductivity in CVD Diamond. 19 Superconductivity in Diamond ( Yoshihiko Takano ). Index.
The Effect of Hydrostatic Pressure on the Rate of Inactivation of Cypridina Luciferase by Specific Antibody (1966)

Summary High pressures, on the order of 1000 atmospheres, were found to have a retarding effect on the rate of inactivation of the enzyme, Cypridina luciferase, by rabbit antibody. The volume change of activation ranged from 9–12 ml/mole at 25.0°C. This small volume change has been interpreted to mean that (a) compensating volume changes are involved or (b) little conformational change takes place in the process of inactivation and that the combining site or sites are readily accessible, instead of being deeply imbedded in the molecules.
USE OF A JUVENILE HORMONE ANALOGUE AGAINST THE FALL WEBWORM, HYPHANTRIA CUNEA (1973)

Administration of 0.1–100 μg of ethyl 11‐chloro‐3,7,11‐trimethyl‐2‐dodecenoate to last‐instar larvae of Hyphantria cunea that have not initiated cocoon spinning induces development of superlarvae and larval‐pupal intermediates. The superlarvae continue feeding and a few of them eventually pupate, but all the intermediates die soon after ecdysis. Spraying of 0.0005–0.5% emulsions of the compound affects the development of Hyphantria under field conditions. As many as 80% of the insects fail to pupate after spraying with 0.5% emulsion and nearly 60% of the insects are affected after spraying 0.05% emulsion. The treatment of larvae with the juvenile hormone analogue seems to have little effect on the development of parasites of Hyphantria. Zusammenfassung VERWENDUNG EINES JUVENILHORMON‐AN ALOGS GEGEN HYPHANTRIA CUNEA Ein Bio‐Analog des Juvenilhormons der Insekten, der 11‐Chloro‐3,7,11‐trimetbyl‐dodec‐2‐en‐karbonsäure‐äthylester verhindert die Umwandlung von Hyphantria ‐Raupen zu Puppen. Die mit 0,1–100 μg der Substanz behandelten Raupen häuten sich entweder zu Riesenraupen eines überzähligen Larvenstadiums oder zu verschiedenen Mischformen zwischen Raupe und Puppe. Je früher im letzten Larvenstadium die Substanz angewendet wird, desto mehr larvale und weniger pupale Merkmale weisen die Tiere nach der Häutung auf; Applikation der Substanz nach dem Einsetzen des Spinnens beeinflußt die Puppenhäutung nicht mehr. Die Mischformen gehen nach der Häutung bald ein, die Riesenraupen aber leben und fressen noch lange Zeit nach der Verpuppung der Kontrolltiere und einige von ihnen häuten sich schließlich zu entwicklungsfähigen Puppen. Bespritzung der Raupen mit 0,0005–0,5%igen Emulsionen der Substanz unter Feldbedingungen (1500 Liter per Hektar Obstgarten) bewirkte ihre Entwicklung in derselben Weise. Die Fraßperiode wurde in einigen Fällen verlängert, aber die Zahl der Puppen war immer reduziert. Die Wirksamkeit der Behandlung wurde entweder im Prozent der morphologisch beeinflußten Tiere (100% = die bis zur Häutung lebenden Tiere) oder in Prozent der nicht‐verpuppten Tiere (nach Abbott gerechnet, 100% = alle Tiere im Versuch) ausgedrückt. Sie erreichte mehr als 80% im Falle der 0,5% igen Emulsion und etwa 60% im Falle der 0,05%‐igen Emulsion. Die Entwicklung der Tachinen in den Raupen und der Befall der Puppen durch parasitische Hymenopteren schien durch den Eingriff nicht beeinflußt.