gebhart/patrepeval huggingface dataset:
Devils in Art: Florence from the Middle Ages to the Renaissance (1997)

Florence has one remarkable distinction, apart from the honour of having given birth to the Renaissance. It has the largest and most terrible image of Satan in all of Europe. First published in 1997, this book has had several reprints due the success which it goes on having, so much so that it is now being reprinted for the 4th time in an updated and improved edition with new photos to further illustrate the fascinating image of a character ever present in Italian paintings. This books considers the meaning and the evolution of the Devil in Medieval and Renaissance Art in Florence, and by means of a careful analysis of the surviving works of art of the period, it pays attention to the least significant artefacts as well as to pictorial works of great importance and beauty.
Using Leader-Based Communication to Improve the Scalability of Single-Round Group Membership Algorithms (2005)

Sigma, the first single-round group membership (GM) algorithm, was recently introduced and demonstrated to operate consistently with theoretical expectations in a simulated WAN environment. Sigma achieved similar quality of membership configurations as existing algorithms but required fewer message exchange rounds. We now consider Sigma in terms of scalability. Sigma involves all-to-all (A2A) type of communication among members. A2A protocols have been shown to perform worse than leader-based (LB) protocols in certain networks, due to greater message overhead and higher likelihood of message loss. Thus, although LB protocols often involve additional communication steps, they can be more efficient in practice, particularly in fault-prone networks with large numbers of participating nodes. In this paper, we present Leader-Based Sigma, which transforms the original all-to-all version into a more scalable centralized communication scheme, and discuss the rounds vs. messages tradeoff involved in optimizing GM algorithms for deployment in large-scale, fault-prone dynamic network environments.
Shadow Identification using Colour Ratios (2000)

In this paper we present a comprehensive method for identifying probable shadow regions in an image. Doing so is relevant to computer vision, colour constancy, and image reproduction, specifically dynamic range compression. Our method begins with a segmentation of the image into regions of the same colour. Then the edges between the regions are analyzed with respect to the possibility that each is due to an illumination change as opposed to a material boundary. We then integrate the edge information to produce an estimate of the illumination field.
Clinical Validation of a Handheld Assistive Device for Tremor (S53.005) (2013)

OBJECTIVE: To demonstrate the effectiveness of a handheld device on reducing tremor, using Active Cancellation of Tremor (ACT) technology.
1 Einleitung (2020)

Erstmals widmet sich ein Buch dem Thema „Beschallung im Kino“. Der Autor erläutert komplexe Zusammenhänge gut verständlich und mit vielen Abbildungen die Schritte zur optimalen Beschallung im Kinosaal. Es geht auf alle relevanten Aspekte wie Raumakustik, Lautsprecher, Verstärker, Tonformate sowie die dafür notwendigen Grundlagen ein. Es ist DIE Pflichtlektüre für alle, die sich beruflich oder privat für ‚guten Ton im Kino‘ interessieren.
Sources of error in UV radiation measurements (2001)

Increasing commercial, scientific, and technical applications involving ultraviolet (UV) radiation have led to the demand for improved understanding of the performance of instrumentation used to measure this radiation. There has been an effort by manufacturers of UV measuring devices (meters) to produce simple, optically filtered sensor systems to accomplish the varied measurement needs. We address common sources of measurement errors using these meters. The uncertainty in the calibration of the instrument depends on the response of the UV meter to the spectrum of the sources used and its similarity to the spectrum of the quantity to be measured. In addition, large errors can occur due to out-of-band, non-linear, and non-ideal geometric or spatial response of the UV meters. Finally, in many applications, how well the response of the UV meter approximates the presumed action spectrum needs to be understood for optimal use of the meters.
Combined factor VII/protein C deficiency results in intrauterine coagulopathy in mice (2000)

To determine whether an additional loss of the coagulation factor VII (FVII) gene influenced the coagulopathy observed in protein C gene-deficient (PC(-/-)) embryos and neonates, we crossed mice doubly heterozygous for the factor VII (FVII(+/-)) and protein C (PC(+/-)) genes to produce offspring possessing the 9 predicted genotypic combinations. FVII(-/-)/PC(-/-) embryos, although present at their expected Mendelian frequency, displayed a phenotype that had not been observed in either the FVII or PC singly deficient embryos. At E12.5 days postcoitum (dpc), FVII(-/-)/PC(-/-) embryos demonstrated an intra- and extravascular coagulopathy that progressed with substantial concomitant hemorrhage and peripheral edema by E17.5dpc, resulting in mortality immediately after birth. FVII(+/-)/PC(-/-) embryos showed a less severe phenotype, suggesting a gene dosage effect. The lack of rescue of PC(-/-) embryos and neonates and augmented coagulopathy resulting from an additional heterozygous or homozygous FVII deficiency are probably due to increased factor Xa and thrombin generation, resulting from loss of FVIIa-dependent tissue factor pathway inhibitor function and the absence of control at the levels of factors Va and VIIIa. The presence of fibrin in embryos in the absence of fetal FVII suggests that significant clot-generating potential exists outside of the embryonic factor VII-dependent pathway.
Query Steering for Interactive Data Exploration (2013)

± ABSTRACT Traditional DBSMs are suited for applications in which the structure, meaning and contents of the database, as well as the questions to be asked are already well understood. There is, however, a class of applications that we will collectively refer to as Interactive Data Exploration (IDE) applications, in which this is not the case. IDE is a key ingredient of a diverse set of discovery-oriented applications we are dealing with, including ones from scientific computing, financial analysis, evidence-based medicine, and genomics. The need for effective IDE will only increase as data are being collected at an unprecedented rate. IDE is fundamentally a multi-step, non-linear process with imprecise end-goals. For example, data-driven scientific discovery through IDE often requires non-expert users to iteratively interact with the system to make sense of and to identify interesting patterns and relationships in large, amorphous data sets. To make the most of the increasingly available complex and big data sets, users would need an expert who would be able to effectively and efficiently them through the data space. Having a human assistant is not only expensive but also unrealistic. Thus, it is essential that we automate this task. We propose systems be augmented with an automated database navigator (DBNav) service that assists as a guide to facilitate IDE. Just like a car navigation system that offers advice on the routes to be taken and display points of interest, DBNav would similarly steer the user towards interesting trajectories through the data, while highlighting relevant features. Like any good tour guide, DBNav should consider many kinds of information; in particular, it should be sensitive to a user's goals and interests, as well as common navigation patterns that applications exhibit. We sketch a general data navigation framework and discuss some specific components and approaches that we believe belong to any such system.
A Similarity Measure for Text Classification and Clustering (2013)

Measuring the similarity between documents is an important operation in the text processing field. In this paper, a new similarity measure is proposed. To compute the similarity between two documents with respect to a feature, the proposed measure takes the following three cases into account: a) The feature appears in both documents, b) the feature appears in only one document, and c) the feature appears in none of the documents. For the first case, the similarity increases as the difference between the two involved feature values decreases. Furthermore, the contribution of the difference is normally scaled. For the second case, a fixed value is contributed to the similarity. For the last case, the feature has no contribution to the similarity. The proposed measure is extended to gauge the similarity between two sets of documents. The effectiveness of our measure is evaluated on several real-world data sets for text classification and clustering problems. The results show that the performance obtained by the proposed measure is better than that achieved by other measures.
Hexakis(PCP-Platinum and -Ruthenium) Complexes by the Transcyclometalation Reaction and Their Use in Catalysis (2002)

Hexakis(PCP-pincer) complexes [C6{PtBr(PCP)}6] (5d) and [C6{RuCl(PCP)(PPh3)}6] (5e) were synthesized via the transcyclometalation (TCM) procedure. Mixing the hexakis(PCHP-arene) ligand 7 with six equivalents of [PtBr(NCN)] (1a) or [RuCl(NCN)(PPh3)] (1b), respectively, resulted in the selective metalation of all PCP-ligand sites and the concomitant formation of six equivalents of the NCHN-arene ligand. This procedure was found to be superior over existing metalation procedures. In addition, hexakisruthenium complex 5e was applied as homogeneous catalyst in the hydrogen transfer reactions of cyclohexanone, acetophenone and benzophenone to the corresponding alcohols. In these reactions, the activity per ruthenium center of 5e was found to be of the same order of magnitude as that of the mononuclear analogue [RuCl(PCP)(PPh3)] 3b, indicating that all ruthenium centers act as independent catalytic sites.
Phenotypic and molecular states of IDH1 mutation-induced CD24-positive glioma stem-like cells (2022)

Mutations in IDH1 and IDH2 drive the development of gliomas. These genetic alterations promote tumor cell renewal, disrupt differentiation states, and induce stem-like properties. Understanding how this phenotypic reprogramming occurs remains an area of high interest in glioma research. Previously, we showed that IDH mutation results in the development of a CD24-positive cell population in gliomas. Here, we demonstrate that this CD24-positive population possesses striking stem-like properties at the molecular and phenotypic levels. We found that CD24 expression is associated with stem-like features in IDH-mutant tumors, a patient-derived gliomasphere model, and a neural stem cell model of IDH1-mutant glioma. In orthotopic models, CD24-positive cells display enhanced tumor initiating potency compared to CD24-negative cells. Furthermore, CD24 knockdown results in changes in cell viability, proliferation rate, and gene expression that closely resemble a CD24-negative phenotype. Our data demonstrate that induction of a CD24-positive population is one mechanism by which IDH-mutant tumors acquire stem-like properties. These findings have significant implications for our understanding of the molecular underpinnings of IDH-mutant gliomas.
Cell sorting with combined optical tweezers and microfluidic chip technologies (2010)

Sorting of specific target cells is an important process in biotechnological research and clinical medicine. This paper proposes a methodology that integrates optical tweezers and microfluidic chip technologies to realize the automatic cell sorting in a continuous flow environment. In the proposed system, cells are driven through the region of interest, and the digital image processing technique is utilized to recognize the target cells. The optical tweezers are used to move the cells selected by image processing to the desired area. In order to move the target cells to the collection reservoir more quickly and reduce the cell-cell interactions (e.g., clustering or jamming), the motion of optical tweezers is further investigated. The relationship between the laser power and the cell maximal escape velocity has been studied to achieve the robust cell sorting with lower power. The idea of multi-trap parallel processing is proposed to achieve high throughput without losing the purity. Utilizing the proposed cell sorter, we can collect rare cells from a sample of primary tissue without expansion, with less damage and higher accuracy.
Infections in patients with aplastic anemia (2003)

Infections remain a major cause of death in patients with AA. Bacterial infections, especially those caused by gram-positive cocci, constitute the main cause of IE. Invasive mold infections, however, are the major cause of death in this patient population.
3868Different prognostic impacts of residual coronary stenosis after percutaneous coronary intervention by left ventricular systolic function in patients with ischemic heart failure (2017)

marked depression of LV systolic function. This was attributed to aggravation of septal function. Future studies should investigate if a similar load dependency is present in hypertensive patients with LBBB and during right ventricular pacing which similar to LBBB, causes abnormal septal motion.
Accounting for source effects in the ShakeMap procedure: the 2000 Tottori and the 2008 Miyagi earthquakes (2013)

Real-time seismology has made significant improvements in recent years, with source parameters now available within a few tens of minutes after an earthquake. It is likely that this time will be further reduced, in the near future, by means of increased efficiency in real-time transmission, increasing data coverage and improvement of the methodologies. In this context, together with the development of new ground motion predictive equations (GMPEs) that are able to account for source complexity, the generation of strong ground motion shaking maps in quasi-real time has become ever more feasible after the occurrence of a damaging earthquake. However, GMPEs may not reproduce reliably the ground motion in the near-source region where the finite fault parameters have a strong influence on the shaking.
Preparation of Synthetic Titania Slag Relevant to the Industrial Smelting Process Using an Induction Furnace (2021)

A high titania slag that is used as a feedstock for TiO2 manufacturing is obtained by ilmenite smelting (FeO.TiO2). The composition of the slag obtained by smelting is dependent on the composition of the mineral used for slag preparation, i.e., ilmenite in our study. At the laboratory scale, ilmenite slags are mostly obtained by using ilmenite as the raw material. An easy and simple way would be to prepare the synthetic slag using the individual components and heating them to high temperature in a furnace. The titania slag has a high oxidizing nature and requires an inert atmosphere to prevent oxidation of the slag as well as the molybdenum crucible. This paper describes the preparation of synthetic ilmenite slag using an induction furnace and the study of the composition and the phases formed in the slag. X-ray powder diffraction (XRD), scanning electron microscopy (SEM), and inductively coupled plasma-optical emission spectroscopy (ICP-OES) were used as analytical techniques for studying the slag. A comparison between obtained synthetic slag and industrial ilmenite slag was performed to test the possibility of preparing slags in the laboratory as per the required composition. The slags show similar phase formation as obtained in industrial ilmenite slags, which means that the synthetic slags are identical to the industrial slags.
Combined Antibacterial Effects of Goat Cathelicidins With Different Mechanisms of Action (2018)

Being essential components of innate immune system, animal antimicrobial peptides (AMPs) also known as host-defense peptides came into sharp focus as possible alternatives to conventional antibiotics due to their high efficacy against a broad range of MDR pathogens and low rate of resistance development. Mammalian species can produce a set of co-localized AMPs with different structures and mechanisms of actions. Here we examined the combined antibacterial effects of cathelicidins, structurally diverse family of host-defense peptides found in vertebrate species. As a model we have used structurally distinct cathelicidins expressed in the leukocytes of goat <i>Capra hircus</i>. The recombinant analogs of natural peptides were obtained by heterologous expression in bacterial system and biological activities as well as the major mechanisms of antibacterial action of the peptides were investigated. As the result, the marked synergistic effect against wide panel of bacterial strains including extensively drug-resistant ones was observed for the pair of membranolytic α-helical amphipathic peptide ChMAP-28 and Pro-rich peptide mini-ChBac7.5Nα targeting a bacterial ribosome. ChMAP-28 was shown to damage the outer bacterial membrane at sub-inhibitory concentrations that could facilitate Pro-rich peptide translocation into the cell. Finally, resistance changes under a long-term continuous selective pressure of each individual peptide and the synergistic combination of both peptides were tested against <i>Escherichia coli</i> strains. The combination was shown to keep a high activity after the 26-days selection experiment in contrast to mini-ChBac7.5Nα used alone and the reference antibiotic polymyxin B. We identified the point mutation leading to amino acid substitution V102E in the membrane transport protein SbmA of the mini-ChBac7.5Nα-resistant strain obtained by selection. The experiments revealed that the presence of sub-inhibitory concentrations of ChMAP-28 restored the activity of mini-ChBac7.5Nα against this strain and clinical isolate with a weak sensitivity to mini-ChBac7.5Nα. The obtained results suggest a potential medical application of synergistic combinations of natural cathelicidins, which allows using a lower therapeutic dose and minimizes the risk of resistance development.
Effects of simvastatin on the angiogenesis of colonic carcinoma xenograft in nude mice (2010)

Objective To investigate the effects of simvastatin on the angiogenesis of colonic carcinoma xenografts in nude mice. Methods Twelve female athymic mice inoculated with human colonic cancer cell line colo-320 subcutaneously were randomly divided into two groups. The treatment group were administrated with simvastatin orally at a dose of 10 mg/kg. The control group were given the same volume of PBS. After 28 days tumor volume were recorded. C-fos, VEGF expression and microvascular density (MVD) of the xenograft tissue were detected by immunohistochemical staining. Results The volume of grafting tumour in treatment group (1.29±0.14)cm3 were significantly lower than those in control group (2.07±0.18)cm3 (P<0.05). C-fos,VEGF and MVD were 2.8±0.7,2.7±0.9,12.7±1.1 in carcinoma tissues treated with simvastatin, which were lower than those(5.8±1.7,4.7±1.5,20.7±1.5,respectively) in control group (P<0.05). Conclusions Simvastatin may suppress angiogenesis of colonic carcinoma xenografts in nude mice via inhibiting C-fos and reducing the expression of VEGF.

Key words: 
Simvastatin ;  Colonic carcinoma ;  Angiogenesis ;
Family planning: humanism and science. (1968)

The author used to believe that social workers had built in resistances to suggesting family planning for clients. Today, however, this is not longer so because of the 1967 resolution on the National Association of Social Workers. There is however, serious concern about furnishing contraceptives or family planning information to the unmarried minor. The author contents that physicians and social workers both have to help youth in the confused area of premarital sexual relations. The abortion problem should involve the same professions. The author argues that a) every woman over 40 should have the right to make up her mind about being pregnant and continuing so, and b) every girl of 17 or less should be allowed an abortion if she is pregnant out of wedlock.
Learning to predict rare events in event sequences (1998)

Learning to predict rare events from sequences of events with categorical features is an important, real-world, problem that existing statistical and machine learning methods are not well suited to solve. This paper describes timeweaver, a genetic algorithm based machine learning system that predicts rare events by identifying predictive temporal and sequential patterns. Timeweaver is applied to the task of predicting telecommunication equipment failures from 110,000 alarm messages and is shown to outperform existing learning methods. Introduction An event sequence is a sequence of timestamped observations, each described by a fixed set of features. In this paper we focus on the problem of predicting rare events from sequences of events which contain categorical (non-numerical) features. Predicting telecommunication equipment failures from alarm messages is one important problem which has these characteristics. For AT&amp;amp;T, where most traffic is handled by 4ESS switches, the specific ...
Effects of feeding factors on dairy performance and milk fatty acid composition in cows and goats (2014)

Conferencia invitada presentada al Proceedings of the 16th AAAP Animal Science Congress Vol. I. (Gadjah Mada University, Yogyakarta, Indonesia, 10-14 noviembre 2014).
Differential expression of cytoskeletal regulatory factors in the adolescent prefrontal cortex: Implications for cortical development (2016)

The prevalence of depression, anxiety, schizophrenia, and drug and alcohol use disorders peaks during adolescence. Further, up to 50% of "adult" mental health disorders emerge in adolescence. During adolescence, the prefrontal cortex (PFC) undergoes dramatic structural reorganization, in which dendritic spines and synapses are refined, pruned, and stabilized. Understanding the molecular mechanisms that underlie these processes should help to identify factors that influence the development of psychiatric illness. Here we briefly discuss the anatomical connections of the medial and orbital prefrontal cortex (mPFC and OFC, respectively). We then present original findings suggesting that dendritic spines on deep-layer excitatory neurons in the mouse mPFC and OFC prune at different adolescent ages, with later pruning in the OFC. In parallel, we used Western blotting to define levels of several cytoskeletal regulatory proteins during early, mid-, and late adolescence, focusing on tropomyosin-related kinase receptor B (TrkB) and β1-integrin-containing receptors and select signaling partners. We identified regional differences in the levels of several proteins in early and midadolescence that then converged in early adulthood. We also observed age-related differences in TrkB levels, both full-length and truncated isoforms, Rho-kinase 2, and synaptophysin in both PFC subregions. Finally, we identified changes in protein levels in the dorsal and ventral hippocampus that were distinct from those in the PFC. We conclude with a general review of the manner in which TrkB- and β1-integrin-mediated signaling influences neuronal structure in the postnatal brain. Elucidating the role of cytoskeletal regulatory factors throughout adolescence may identify critical mechanisms of PFC development. © 2016 Wiley Periodicals, Inc.