gebhart/patrepeval huggingface dataset:
Fast Semantic Attribute-Role-Based Access Control (ARBAC) (2013)

expressive power to ensure logical consistency. We used a modified Attribute-Role-Based Access Control (ARBAC) security model and an OWL ontology with additional rules in a logic programming framework to express access policy, going beyond the limitations of previous attempts in this vein, and then optimized with bit-vectors the runtime policy checking inference. We focused on three aspects: expressivity, adaptability, and efficiency. We developed two implementations: one that transforms the policy model instance into a logic programming execution environment that includes rules; and a second that transforms the model instance into Java data structures, that in turn are optimized via a bit-encoding. In both cases, the prototype was embedded in a Java program that interfaces with external services, e.g., obtaining identity and access tokens (and their specific attribute information) from the authentication service.
Flexible and washable conductive textile achieved by screen printing for smart fabric applications (2013)

providing many different functions. 2. Well established technology in textile. 3. Straight forward and low cost. 4. Versatility of design especially for fine geometries. 5. Ease of fabrication of multi-layer functional devices. • Electrical interconnections (e.g. fabric PCB, left) • Functional electronic elements (e.g. fabric heater, right) 1. Reduce the usage of the expensive silver paste. 2. Improve the reproducibility. 3. Provide protection underneath conductive tracks.
Skin rejuvenation using cosmetic products containing growth factors, cytokines, and matrikines: a review of the literature (2016)

Skin aging is primarily due to alterations in the dermal extracellular matrix, especially a decrease in collagen I content, fragmentation of collagen fibrils, and accumulation of amorphous elastin material, also known as elastosis. Growth factors and cytokines are included in several cosmetic products intended for skin rejuvenation because of their ability to promote collagen synthesis. Matrikines and matrikine-like peptides offer the advantage of growth factor-like activities but better skin penetration due to their much smaller molecular size. In this review, we summarize the commercially available products containing growth factors, cytokines, and matrikines for which there is evidence that they promote skin rejuvenation.
Indexing emails and email threads for retrieval (2005)

Electronic mail poses a number of unusual challenges for the design of information retrieval systems and test collections, including informal expression, conversational structure, variable document granularity (e.g., messages, threads, or longer-term interactions), a naturally occuring integration between free text and structural metadata, and incompletely characterized user needs. This paper reports on initial experiments with a large collection of public mailing lists from the World Wide Web consortium that will be used for the TREC 2005 Enterprise Search Track. Automatic subject-line threading and removal of duplicated text were found to have little effect in a small pilot study. Those observations motivated development of a question typology and more detailed analysis of collection characteristics; preliminary results for both are reported.
Protein adsorption on polyurethane catheters modified with a novel antithrombin‐heparin covalent complex (2006)

Highly anticoagulant covalent antithrombin-heparin complex (ATH) was covalently grafted onto polyurethane catheters to suppress adsorption/activation of procoagulant proteins and enhance adsorption/activation of anticoagulant proteins for blood compatibility. Consistency of catheter coating was demonstrated using immunohistochemical visualization of ATH. The ability of the resulting immobilized ATH heparin chains to bind antithrombin (AT) from plasma, as measured by binding of (125)I-radiolabeled AT, was greater than that for commercially-available heparin-coated catheters, and much greater than for uncoated catheters. Complementary measurements of antifactor Xa (FXa) activity and plasma protein binding were also performed. Both ATH-coated and heparin-coated catheters demonstrated functional binding of exogenous AT. However, the ATH-coated catheters gave a trend towards elevated anti- FXa activities/AT binding ratios, consistent with the higher active pentasaccharide content in starting ATH. Western blot analysis of proteins adsorbed to catheters after incubation with rabbit plasma established protein binding profiles that showed AT and albumin as major plasma proteins adsorbed to ATH-coated catheters, while AT and altered forms of fibrinogen were major plasma protein species adsorbed to heparinized catheters.
Endoclips as a Novel Treatment for Massive Rectal Bleeding Following Prostate Biopsy (2008)

Purpose: Transrectal ultrasound (TRUS)- guided systematic sextant needle biopsy of the prostate is considered a safe and common modality of detecting prostate cancer. However, massive rectal bleeding requiring emergent intervention has not been documented or readily described. Methods: A 52 year old male underwent a prostate biopsy. The patient was then taken to the recovery room. While in recovery, the patient had 2 large bloody bowel movements. Results: Within minutes, a large bed pan was filled with bright red blood. An emergent sigmoidoscopy was then performed. Immediately, copious red blood with clots were identified. Two centimeters proximal to the dentate line, a pulsatile arterial jet of blood was seen. Seven milliliters of epinephrine was injected to this area, and the bleeding slowed to gain visibility. Two endoclips were then placed on the biopsy site and hemostasis was achieved. The patient was then sent to interventional radiology to ensure complete hemostasis. Conclusion: In one review of 5802 prostate biopsies, not a single episode of massive rectal bleeding was described. However, in another review of the literature, Strate, Oleary, et. al did describe 17 case reports of severe rectal bleeding. According to them, the most frequently applied method of bleeding control was balloon tamponade. Brullet, Guervara, et. al only report one case of life-threatening bleeding. However, none of these authors described the use of endoclips as a primary intervention to obtain hemostasis. In our case, once the bleeding vessel was identified, endoclips were placed directly on the pulsating artery, and direct visual hemostasis was obtained. We suggest that colonoscopy with the use of endoclips to obtain hemostasis is an effective and novel approach for treatment of massive rectal bleeding following prostate biopsy.Figure: The angiogram proved that there was no active rectal bleeding following endoscopic endoclip placement on left middle and inferior hemorrhoidal arteries.
Interactions of nucleic acids with fluorescent dyes: spectral properties of condensed complexes. (1990)

Interaction of cations with nucleic acids (NA) often results in condensation of the product. The driving force of aromatic cation-induced condensation is the cooperative interaction between ligand and single-stranded (ss) NA. This type of reaction is highly specific with regard to the primary and secondary structure of NA, and results in destabilization of the latter. The spectral properties of fluorescent intercalating and non-intercalating ligands [acridine orange, pyronin Y(G), DAPI, Hoechst 33258, and Hoechst 33342]-NA complexes were studied in both the relaxed and condensed form. The changes in absorption, excitation, and fluorescence emission spectra and fluorescence yield that followed the condensation were examined. Although some of these effects can be explained by changes in solvation of the fluorophore and its interaction with NA bases and the solvent, the overall effect of condensation on spectral properties of the complex is unpredictable. In particular, no correlation was found between these effects and the ds DNA binding mode of these ligands. Nevertheless, the spectral data associated with polymer condensation can yield information about the composition and structure of NA and can explain some nonspecific interactions of these probes.
Liquid‐liquid‐phase Synthesis of exo‐Vinylene Carbonates from Primary Propargylic Alcohols: Catalyst Design and Recycling (2020)

Abstract A straight‐forward approach to separate catalyst from the exo ‐vinylene carbonate (EVC) products of the carboxylative cyclisation of primary propargylic alcohols has been developed. The liquid‐liquid phase synthesis utilises lipophilic silver(I) carboxylate salts and N,N ‐dioctyl modified phosphine (FatPhos) ligands to enhance catalyst solubility in non‐polar solvents. Following simple liquid‐liquid phase separation, EVCs relevant as monomers for poly(urethane) and poly(carbonate) synthesis were isolated in the non‐miscible polar phase in good yields. In situ reaction monitoring by ReactIR gave insights into the reaction kinetics and informed the conditions used to afford good EVC selectivity. Under optimised conditions, silver leaching into the product phase was very minor as confirmed by ICP‐MS. Furthermore, a protocol for catalyst recycling by liquid‐liquid separation was demonstrated, with modest loss of catalytic activity over 3 runs.
Conception d'une antenne adaptée à un RADAR GPR pour une utilisation sur un tunnelier ". (2013)

International audience
Areas of Attention for Image Captioning (2017)

We propose “Areas of Attention”, a novel attentionbased model for automatic image captioning. Our approach models the dependencies between image regions, caption words, and the state of an RNN language model, using three pairwise interactions. In contrast to previous attentionbased approaches that associate image regions only to the RNN state, our method allows a direct association between caption words and image regions. During training these associations are inferred from image-level captions, akin to weakly-supervised object detector training. These associations help to improve captioning by localizing the corresponding regions during testing. We also propose and compare different ways of generating attention areas: CNN activation grids, object proposals, and spatial transformers nets applied in a convolutional fashion. Spatial transformers give the best results. They allow for image specific attention areas, and can be trained jointly with the rest of the network. Our attention mechanism and spatial transformer attention areas together yield state-of-the-art results on the MSCOCO dataset.
Monitoring of actuation conditions in a micro-turbo-generator (2013)

This paper presents the theory and implementation of an integrated sensing technique for the real-time measurement of applied actuation conditions in a micro-turbo-generator. The device is composed of a microturbine rotor with magnetic components and a stator with planar coils for electromagnetic induction. While the rotor is actuated with pressurized nitrogen, the induced voltages are extracted to generate and deliver electrical power as well as to monitor the pneumatic actuation parameters. It is demonstrated that the rotor speed, applied gas flow rate, and pressure show repeatable high linearity with respect to voltage frequency and amplitude in different devices. Sensitivity values of 83 Hz/krpm, 140 Hz/slm, and 1428 Hz/psi together with R <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> values larger than 0.97 are achieved. The integrated sensing technique presented in this paper will eliminate the need for external sensing components in continuous device screening, and lead to closed-loop control for autonomous tuning of desired operating conditions in rotary microgenerators.
Model for the development of a low cost thermal mass flow meter (2012)

Se presenta el modelo matematico para el desarrollo de un medidor de flujo masico. Su principio de operacion esta basado en una relacion entre el flujo de calor suministrado a la seccion de prueba y la diferencia de temperaturas entre la entrada y la salida. Un modelo numerico del comportamiento termico y fluido-dinamico del medidor termico de flujo masico es desarrollado; las ecuaciones gobernantes dentro del tubo (continuidad, momentum y energia) junto con la ecuacion de la energia en la pared del tubo y el aislante han sido resueltas iterativamente y de una forma segregada. El estudio parametrico desarrollado con el modelo numerico incluye el diametro, longitud del tubo asi como la potencia suministrada al sistema; con los resultados numericos obtenidos y tomando en cuenta algunas restricciones sobre el sistema, el diseno final se obtuvo y se construyo. Se llevo a cabo un procedimiento de pruebas para mostrar la factibilidad tecnica de sistema y se encontro un error en la medicion de flujo de ±0.55%. En relacion con el costo de construccion, los errores de las mediciones experimentales son aceptables si se comparan con algunos de los medidores comerciales mas comunmente usados de mayor precio
Synthesis, Biological and In Silico Studies of Griseofulvin and Usnic Acid Sulfonamide Derivatives as Fungal, Bacterial and Human Carbonic Anhydrase Inhibitors (2023)

Carbonic anhydrases (CAs, EC 4.2.1.1) catalyze the essential reaction of CO<sub>2</sub> hydration in all living organisms, being actively involved in the regulation of a plethora of patho-/physiological conditions. A series of griseofulvin and usnic acid sulfonamides were synthesized and tested as possible CA inhibitors. Since β- and γ- classes are expressed in microorganisms in addition to the α- class, showing substantial structural differences to the human isoforms they are also interesting as new antiinfective targets with a different mechanism of action for fighting the emerging problem of extensive drug resistance afflicting most countries worldwide. Griseofulvin and usnic acid sulfonamides were synthesized using methods of organic chemistry. Their inhibitory activity, assessed against the cytosolic human isoforms hCA I and hCA II, the transmembrane hCA IX as well as β- and γ-CAs from different bacterial and fungal strains, was evaluated by a stopped-flow CO<sub>2</sub> hydrase assay. Several of the investigated derivatives showed interesting inhibition activity towards the cytosolic associate isoforms hCA I and hCA II, as well as the three γ-CAs and <i>Malassezia globosa</i> (MgCA) enzyme. Six compounds (<b>1b</b>-<b>1d</b>, <b>1h, 1i</b> and <b>1j</b>) were more potent than AAZ against hCA I while five (<b>1d</b>, <b>1h</b>, <b>1i</b>, <b>1j</b> and <b>4a</b>) showed better activity than AAZ against the hCA II isoform. Moreover, all compounds appeared to be very potent against MgCA with a Ki lower than that of the reference drug. Furthermore, computational procedures were used to investigate the binding mode of this class of compounds within the active site of human CAs.
An above-knee prosthesis with a system of energy recovery: a technical note. (1995)

Knee flexion to 24 degrees during early stance transforms kinetic energy into potential energy of a total center of mass (TCM) position. Flexion is controlled by the musculoligamentous apparatus. Reproduction of such flexion in a new single-axis prosthesis knee unit has minimized the metabolic energy cost to the patient by a more favorable use of gravity acting upon the prosthetic segments and the body as well as of inertia. Potential energy is stored in the spring shock absorber of the knee unit. The coefficient of energy recovery increased by 30% in comparison with a conventional above-knee prosthesis. Energy costs to the patient decrease an average of 35% during gait with the new prosthesis. The same amount of unloading during walking is typical of an intact limb. The knee unit mechanism has a link set on the axle, thus providing two joints with a common axis: a) the main joint for knee flexion to 70 degrees during swing phase and flexion to 135 degrees during sitting; b) the second joint for bending at the beginning of stance phase. Compared with conventional units, gait with the new unit displays several functional advantages: 1) normal knee kinematics with movement of a TCM along a trajectory that contributes to an easy rollover of the foot and smooth and continuous translation of the body; 2) shock absorption during early stance prevents impact from the anterior brim of the socket; 3) at mid-stance, the increase of the TCM position accumulates potential energy that results in a significant increase of the push-off force; 4) during rapid gait, the unit provides adequate resistance to knee flexion; 5) location of the joint axis in front of the line of gravity loads the prosthesis in standing, making possible unimpeded carrying of the prosthesis over the support, the lengths of the prosthetic and the intact limb being equal; in addition, it facilitates flexion before the beginning of the swing phase. Production of the units began in 1992.
Rapid high‐resolution electrophoresis of multimeric von Willebrand Factor using a thermopiloted gel apparatus (2003)

Rapid and highly reproducible nonreducing agarose gel electrophoresis (NRAGE) of von Willebrand Factor (vWF) multimers was performed using a thermostated minigel apparatus that monitors and precisely controls internal gel temperature. The substitution of lithium dodecyl sulfate (LiDS) for sodium dodecyl sulfate (SDS) allowed electrophoresis to be performed below the 16 degrees C Krafft point of SDS and facilitated NRAGE of vWF over the entire range of 0-35 degrees C. Internal gel temperature was regulated by a thermocouple probe inserted directly into the gel during electrophoresis which interfaced with a thermopilot that continually measures and adjusts temperature to within +/- 0.5 degrees C. At 10 degrees C operative temperature, NRAGE at 1.5% agarose concentration was completed in 20 min at 250 V. Electrophoresis could be performed in only 10 min at 500 V, but at such high voltages, localized temperature fluctuations as much as 6 degrees C resulted in perturbation of banding patterns in those vicinities. In the optimized method, both high molecular weight multimers and proteolytic fragments of vWF were separable suggesting clinical applicability of this system for the diagnosis of von Willebrand Disease and thrombotic thrombocytopenic purpura.
High-field Zeeman contribution to the trion binding energy (2002)

We examine the role of the Zeeman interaction in determining the bound states of the trion at magnetic fields up to 50 T. Polarization-sensitive photoluminescence measurements on the singlet state of the positively charged trion ${(X}^{+})$ in GaAs quantum wells demonstrate a 60% enhancement of the g factor compared to that of the neutral exciton ${(X}_{0})$ in the same sample. This leads to a situation in very high fields where the Zeeman splitting of ${X}^{+}$ is sufficiently large to determine whether a state is bound or not, and so calls for a re-examination of what is meant by the binding energy of few particle systems.
The tubB alpha-tubulin gene is essential for sexual development in Aspergillus nidulans. (1991)

The filamentous fungus Aspergillus nidulans has two genes encoding alpha-tubulin, tubA and tubB. Mutational analysis of tubA has demonstrated that the tubA gene is essential for mitosis and nuclear migration. In this study we have deleted the tubB gene by replacing it with a selectable marker and have named this new allele tubB delta. The results demonstrate that the tubB gene is not required for vegetative growth or asexual reproduction, nor is it required for the initiation or early stages of sexual differentiation. Deletion of tubB, however, completely prevents ascosporogenesis, because tubB delta strains produce no sexual spores when self-crossed. These strains produce viable ascospores when outcrossed to tubB+ strains, indicating that the tubB delta mutation is recessive. We have studied the cytology of sexual development in wild-type strains and in the tubB mutant and have observed that tubB delta. strains develop normally to the stage of ascus formation. However, only a single nuclear mass is observed in the tubB delta ascus, indicating that either the two zygotic haploid nuclei are blocked in karyogamy or that karyogamy occurs but the resulting diploid nucleus is subsequently blocked in meiosis I.
Sparse Structure-Based Channel Estimation for Uplink SCMA System (2017)

To fully utilize the performance gain of sparse code multiple access (SCMA) system, the channel state information of multiusers must be obtained at the base station. However, conventional channel estimation approach causes significant training overhead as the number of active users becomes large. In this paper, we propose a channel estimation scheme for the uplink SCMA system to reduce the training overhead, which is based on the unstructured channel estimator (UCE). However, it is ineffective in terms of the resource usage to apply the UCE scheme to the SCMA system directly since the data detection requires only channel information on the nonzero subcarriers of the SCMA codeword. Thus, we introduce a sparse pilot structure where the location of nonzero pilot symbols correspond to the location of nonzero symbols in the SCMA codeword and provide an optimal pilot allocation scheme for the sparse pilot structure, which can achieve the mean square error lower bound. In addition, we consider the codebook reuse scenario to support more users with the existing SCMA codebooks. While the codebook reuse can help realize the massive connectivity, it has a problem that interference on each resource grows irregularly, which in turn leads to overwhelming training overhead. To solve this problem, we propose a channel estimation approach to reduce interference per subcarrier uniformly by the weight-regularization (WR) algorithm, and apply the optimal pilot allocation and least squares algorithm. The puncturing channel information by the WR algorithm can be obtained by a minimum mean square error (MMSE) interpolator or a combined interpolator. Analytical results and simulations shows effectiveness of the proposed channel estimators.
A Multipath Transmission System for Information-Centric Networking Based on Standalone Name Resolution (2023)

Information-Centric Networking (ICN) essentially supports multipath transmission. However, current multipath schemes in ICN either necessitate major network infrastructure updates or necessitate specific network settings for terminal devices. To solve these problems, we propose MPTS-ICN, a multipath transmission system for ICN that realizes end-to-end multipath transmission. Taking the ICN architecture based on the standalone name resolution approach as a basis, MPTS-ICN is easier to implement and deploy than other ICN multipath schemes. Moreover, we have extended the original network layer protocol to support multipath data transmission in ICN. To set up concurrent transmission multipath efficiently, we propose a heuristic algorithm for the selection of multipath service nodes. Extensive experimental comparisons with existing data transmission methods show that in bandwidth-constrained scenarios, MPTS-ICN outperforms the best-route method by 83.6% and the ECMP method by 79.7% in average flow completion time.
Supplementary Figure 5 from T-Cell Exhaustion Signatures Vary with Tumor Type and Are Severe in Glioblastoma (2023)

&lt;p&gt;Immune checkpoint and cytokine expression on human GBM CD4+ TIL&lt;/p&gt;