gebhart/patrepeval huggingface dataset:
Expression of a rice homeobox gene causes altered morphology of transgenic plants. (1993)

We have isolated a cDNA clone encoding a homeobox sequence from rice. DNA sequence analysis of this clone, which was designated as Oryza sativa homeobox 1 (OSH1), and a genomic clone encoding the OSH1 sequence have shown that the OSH1 gene consists of five exons and encodes a polypeptide of 361 amino acid residues. Restriction fragment length polymorphism analysis has shown that OSH1 is a single-copy gene located near the phytochrome gene on chromosome 3. Introduction of the cloned OSH1 gene into rice resulted in altered leaf morphology, which was similar to that of the maize morphological mutant Knotted-1 (Kn1), indicating that OSH1 is a rice gene homologous to the maize Kn1 gene. RNA gel blot analysis has shown that the gene is primarily expressed in the shoot apices of young rice seedlings. This finding is supported by results of transformation experiments in which the 5' flanking region of the gene directed expression of a reporter gene in the shoot apex, particularly in stipules, of transgenic Arabidopsis. To elucidate the biological function of the OSH1 gene product, the coding region was introduced into Arabidopsis under the control of the cauliflower mosaic virus 35S promoter. Almost all transformants showed abnormal morphology. The typical phenotype was the formation of clumps of abundant vegetative and reproductive shoot apices containing meristems and leaf primordia, which did not form elongated shoots. Some transformants with a less severe phenotype formed elongated shoots but had abnormally shaped leaves and flowers with stunted sepals, petals, and stamens. The abnormal phenotypes were inherited, and the level of expression of the introduced OSH1 correlates with the severity of the phenotype. These findings indicate that the abnormal morphologies of the transgenic plants are caused by the expression of the OSH1 gene product and, therefore, that OSH1 is related to the plant development process.
ExerTrack—Towards Smart Surfaces to Track Exercises (2020)

The concept of the quantified self has gained popularity in recent years with the hype of miniaturized gadgets to monitor vital fitness levels. Smartwatches or smartphone apps and other fitness trackers are overwhelming the market. Most aerobic exercises such as walking, running, or cycling can be accurately recognized using wearable devices. However whole-body exercises such as push-ups, bridges, and sit-ups are performed on the ground and thus cannot be precisely recognized by wearing only one accelerometer. Thus, a floor-based approach is preferred for recognizing whole-body activities. Computer vision techniques on image data also report high recognition accuracy; however, the presence of a camera tends to raise privacy issues in public areas. Therefore, we focus on combining the advantages of ubiquitous proximity-sensing with non-optical sensors to preserve privacy in public areas and maintain low computation cost with a sparse sensor implementation. Our solution is the ExerTrack, an off-the-shelf sports mat equipped with eight sparsely distributed capacitive proximity sensors to recognize eight whole-body fitness exercises with a user-independent recognition accuracy of 93.5% and a user-dependent recognition accuracy of 95.1% based on a test study with 9 participants each performing 2 full sessions. We adopt a template-based approach to count repetitions and reach a user-independent counting accuracy of 93.6%. The final model can run on a Raspberry Pi 3 in real time. This work includes data-processing of our proposed system and model selection to improve the recognition accuracy and data augmentation technique to regularize the network.
Are Standard Human Coagulation Tests Suitable in Pigs and Calves During Extracorporeal Circulation? (2001)

The thrombogenicity of membrane oxygenators as well as clotting parameters profiles, using standard human clotting tests, was analyzed in calves and pigs during 6 h perfusion. Three calves and 3 pigs were connected to extracorporeal circulation with standard heparinization. Blood samples were taken for coagulation variables throughout perfusion, and oxygenators were examined for clot deposits at the end of the experiment. Two out of 3 oxygenators of the calf group presented clot deposits while none in the pig group did. Baseline coagulation variables of pigs showed values similar to those of humans while neither extrinsic nor intrinsic pathways could be activated in calves with standard human coagulation tests. The calf model, in conclusion, was confirmed to be a difficult model for the testing of extracorporeal circulation device resistance to thrombus formation, which is, however, not reflected by standard human coagulation tests. The pig model is a better model in which both coagulation pathways could be activated with standard human coagulation tests.
Electrochemistry (1980)

Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued.
Modulation of Structural Protein Content of the Myotendinous Junction Following Eccentric Contractions (2000)

The objective of this study was to test the hypothesis that vinculin and talin, two cytoskeletal proteins of the myotendinous junction (MTJ), would be up-regulated following damaging eccentric contractions. Mouse plantar flexor muscles were submitted in situ to three 5 min periods of eccentric contractions. Talin and vinculin content, in vitro contractile properties and MTJ histology were examined at 0, 3, 7, 14, and 28 days post-exercise. The eccentric protocol led to significant decreases in maximum tetanic tension at 0, 3, and 7 days post-protocol. Histological examination did confirm that tissue damage was present at the MTJ where talin and vinculin are highly concentrated. In the type I soleus muscle talin content increased slightly at 7 days post-eccentric protocol compared to SHAM. In the type II plantaris muscle eccentric contraction led to an increase for vinculin and talin contents that was 2-3 fold higher than in the soleus; these significant changes were still present 28 days postexercise. These results show that eccentric contractions can trigger intense protein synthesis activity at the MTJ most likely related to myofibrillogenesis associated with MTJ remodeling.
Tartan: A retrieval-based socialbot powered by a dynamic finite-state\n machine architecture (2018)

This paper describes the Tartan conversational agent built for the 2018 Alexa\nPrize Competition. Tartan is a non-goal-oriented socialbot focused around\nproviding users with an engaging and fluent casual conversation. Tartan's key\nfeatures include an emphasis on structured conversation based on flexible\nfinite-state models and an approach focused on understanding and using\nconversational acts. To provide engaging conversations, Tartan blends\nscript-like yet dynamic responses with data-based generative and retrieval\nmodels. Unique to Tartan is that our dialog manager is modeled as a dynamic\nFinite State Machine. To our knowledge, no other conversational agent\nimplementation has followed this specific structure.\n
Application of decision tree in classifying mangrove natural reserve SPOT image (2008)

It is a good result to classify Zhangjiangkou National Mangrove Reserve SPOT image by means of decision tree and to resolve the difficulty to divide Mangrove and fruit trees by traditional supervised method.
Interleukin-10 Suppresses Tissue Factor Expression in Lipopolysaccharide-Stimulated Macrophages via Inhibition of Egr-1 and a Serum Response Element/MEK-ERK1/2 Pathway (2005)

Atherosclerosis is considered to be an inflammatory disease. Tissue factor (TF), a prothrombotic molecule expressed by various cell types within atherosclerotic plaques, is thought to play an essential role in thrombus formation after atherosclerotic plaque rupture. Recent studies suggest that the antiinflammatory cytokine interleukin-10 (IL-10) has many antiatherosclerotic properties. Therefore, the effects of IL-10 on TF expression in response to inflammation were investigated. Mouse macrophages were stimulated with lipopolysaccharide (LPS) in the presence or absence of IL-10. Pretreatment with IL-10 resulted in a 50% decrease in TF mRNA expression and TF promoter activity. Binding of early growth response gene-1 (Egr-1) to the consensus DNA sequence, a key transcriptional activator of TF expression in response to inflammation, and the expression of Egr-1 mRNA were also inhibited by IL-10. This inhibition was independent of the induction of suppressor of cytokine signaling protein-3 by IL-10. Macrophages that had been transfected with luciferase reporter constructs containing the murine Egr-1 5'-flanking sequence exhibited reduced reporter gene activity in response to LPS stimulation with IL-10 pretreatment. Studies with deletion constructs of the Egr-1 promoter identified the proximal serum response element SRE3 as a potential regulatory site for the IL-10 mediated suppression of Egr-1 expression. Furthermore, activation of the upstream signal-transduction elements, such as mitogen-activated protein kinase kinase (MEK) 1/2, extracellular signal-regulated kinase 1/2, and Elk-1 were also inhibited by IL-10 pretreatment. Taken together, these results demonstrate a pathway for the IL-10 mediated inhibition of TF expression during inflammation and may explain the antiatherosclerotic effects of IL-10.
Successful Treatment with Peginterferon alfa-2b of HBeAg-positive HBV Non-Responders to Standard Interferon or Lamivudine (2006)

Peg-IFN alpha2b is effective in approximately one-third of patients who failed to respond to previous treatment with standard IFN or lamivudine. High serum ALT level at baseline of Peg-IFN alpha2b therapy was the best predictor for response in these patients.
5 Total synthesis of the major phytocannabinoids (2023)

As presented in the previous chapters, the cannabis plant is rich in a variety of constituents belonging to many different chemical classes. The most important and characteristic class, specific to cannabis, is the cannabinoids. While a few naturally occurring cannabinoids are abundant in the plant materials, especially Δ9-tetrahydrocannabinol and cannabidiol, other cannabinoids are present in small quantities. Synthesis of cannabinoids, like most other natural products, has been one of the methods used for structure elucidation. However, synthesis is also used to produce large supply of natural products that might not be feasible by isolation from plant material. This chapter is dedicated to methods used to synthesize the major cannabinoids that could be used for product development efforts of these cannabinoids. The synthetic routes offer alternative methods to secure drug supply of these cannabinoids. Only examples of synthetic methods are given, with no intention to provide exhaustive coverage of all literature procedures.
Several key technologies in particle-in-cell (PIC) simulation software (2007)

In current particle-in-cell (PIC) simulation software, the most important parts are several key technologies. In this paper, we discuss some technologies based on Yee-grid model and time-leapfrog model. Firstly, we induce 3-D electromagnetic discrete algorithm formulae, which include the centered-difference algorithm formulae, time-biased algorithm formulae and high-Q algorithm formulae. The application range of these electromagnetic discrete algorithms is also analyzed. Secondly, we discuss the phenomenological description technology used in emission simulations and induce the formulae which represent how to set the charge of macro particles in explosive emission. The charge-conserving algorithm used to calculate current which is produced by the particle moving and the weight algorithm used to calculate Lorentz force are also discussed. Thirdly, the ways to realize the common boundary conditions including the ideal conductor, port boundary, absorption boundaries and metal strut are discussed. The way to calculate the absorption coefficient of the absorption boundary is described in detail. The formulae of the metal strut's current and inductance under two-dimensional and three-dimensional coordinates in different orientation in space are induced and realized using finite-difference time-domain (FDTD) method. Then, the iterative process under main FDTD iteration of metal strut is given. At last, the correctness of these technologies is proved by computer simulation on the Vavilov-Cherenkov radiation (VCR) in 2-D photonic crystal. The results show that the THz radiation is excited by electron bunches in photonic crystal.
Molecular Genetics of Populations of Intracellular Bacteria: The Spotted Fever Group Rickettsiae (1990)

The population structure of tick-borne rickettsiae show the following characteristics: (1) the amount of genetic differentiation between strains within subpopulations is very small. (2) The evolution of the subpopulations does not fit into models based on either host or geographic similarities, suggesting the need for more information on the frequency of vertical versus horizontal transmission of strains between hosts. (3) The species are highly clonal, with little evidence of genetic exchange between populations. (4) The dominant class of genetic change is single-nucleotide point mutation. No evidence for major rearrangements was observed. (5) Differentiation between species of the spotted fever group is equivalent to that seen between local strains of E. coli.
Development of Temperature-Stable RF Filters on Composite Substrates Based on a Single Crystal LiTaO3 Layer on Silicon (2019)

In this paper, we present a new generation of substrates which address the demand for versatile intermediate-to-large-band surface acoustic wave devices and provides a unique solution for temperature-stable filter with excellent spectral qualities. The Piezoelectric-On-Insulator (POI) layer structure provides a breakthrough solution for addressing modern filter challenges on an extended range of specification. An implementation example is presented for a GPS filter at 1.575 GHz exhibiting a TCF smaller than 10 ppm.K <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-1</sup> .
Geophysical constraints on the properties of a subglacial lake in northwest Greenland (2021)

Abstract. In this study, we report the results of an active-source seismology and ground-penetrating radar survey performed in northwestern Greenland at a site where the presence of a subglacial lake beneath the accumulation area has previously been proposed. Both seismic and radar results show a flat reflector approximately 830–845 m below the surface, with a seismic reflection coefficient of −0.43 ± 0.17, which is consistent with the acoustic impedance contrast between a layer of water and glacial ice. Additionally, in the seismic data we observe an intermittent lake bottom reflection arriving between 14–20 ms after the lake top reflection, corresponding to a lake depth of approximately 10–15 m. A strong coda following the lake top and lake bottom reflections is consistent with a package of lake bottom sediments although its thickness and material properties are uncertain. Finally, we use these results to conduct a first-order assessment of the lake origins using a one-dimensional thermal model and hydropotential modeling based on published surface and bed topography. Using these analyses, we narrow the lake origin hypotheses to either anomalously high geothermal flux or hypersalinity due to local ancient evaporite. Because the origins are still unclear, this site provides an intriguing opportunity for the first in situ sampling of a subglacial lake in Greenland, which could better constrain mechanisms of subglacial lake formation, evolution, and relative importance to glacial hydrology.
The Dynamics of a Hooke's Joint Gyroscope with Non-Orthogonal Flexure Axes (1978)

The dynamical characteristics of a Hooke's joint gyroscope with non-orthogonal flexure axes are described. The natural frequencies of the gyroscope are shown to vary with the amount of non-orthogonality present, but the tuning conditions and the conditions for the suppression of drift resulting from twice spin speed angular vibration are shown to be independent of non-orthogonality. For both the tuned and untuned cases, the response to an applied rate of turn has been assessed and errors arising from flexure axis non-orthogonality are identified.
Modifiable lifestyle factors that could reduce the incidence of colorectal cancer in New Zealand. (2016)

If obesity, alcohol consumption, smoking and consumption of red and processed meats could be reduced, and physical activity could be increased among New Zealanders, it would reduce the risk of colorectal cancer considerably.
Outcomes of Rapid Defibrillation by Security Officers after Cardiac Arrest in Casinos (2000)

Rapid defibrillation by nonmedical personnel using an automated external defibrillator can improve survival after out-of-hospital cardiac arrest due to ventricular fibrillation. Intervals of no more than three minutes from collapse to defibrillation are necessary to achieve the highest survival rates.
Short-term noise annoyance and electrodermal response as a function of sound-pressure level, cognitive task load, and noise sensitivity. (2021)

The results suggest that noise annoyance depends on the primary activity the listener is engaged in. They demonstrate that phasic skin conductance responses may serve as an objective correlate of the degree of annoyance experienced. Finally, noise sensitivity is once more shown to augment annoyance ratings in an additive fashion.
Ultra Stable Camera Platforms (1963)

Stable Camera Platforms remove excessive camera motion, thereby preventing image blur while holding the camera steady and positioned in space to a desired attitude. The various cost factors involved in stable camera platform design are discussed.
Catheter-based renal denervation versus intensified medical treatment in patients with resistant hypertension: Rationale and design of a multicenter randomized study-PRAGUE-15 (2014)

KatetrovĂĄ renĂĄlnĂ­ denervace (RDN) byla povaĹžovĂĄna za nadÄjnou metodu pro lĂŠÄbu rezistentnĂ­ hypertenze a poÄet vĂ˝konĹŻ se celosvÄtovÄ stĂĄle navyĹĄoval. Doposud byly publikovĂĄny s rozdĂ­lnĂ˝mi vĂ˝sledky pouze dvÄ randomizovanĂŠ studie, kterĂŠ hodnotĂ­ efekt tĂŠto intervence oproti medikamentĂłznĂ­ lĂŠÄbÄ. Proto jsou nutnĂŠ dalĹĄĂ­ peÄlivÄ designovanĂŠ srovnĂĄvacĂ­ studie. Studie PRAGUE-15 byla navrĹžena jako otevĹenĂĄ prospektivnĂ­ randomizovanĂĄ multicentrickĂĄ studie srovnĂĄvajĂ­cĂ­ ĂşÄinek RDN s intenzifikovanou medikamentĂłznĂ­ lĂŠÄbou u pacientĹŻ s rezistentnĂ­ hypertenzĂ­. Pacienti randomizovanĂ­ do medikamentĂłznĂ­ vÄtve budou uĹžĂ­vat v lĂŠÄbÄ spironolacton, pokud k tomu nebudou ĹžĂĄdnĂŠ kontraindikace. PrimĂĄrnĂ­ cĂ­lovĂ˝ ukazatel studie byl stanoven jako zmÄna hodnot systolickĂŠho a diastolickĂŠho tlaku bÄhem 24hodinovĂŠho ambulantnĂ­ho monitorovĂĄnĂ­ krevnĂ­ho tlaku (ABPM) mezi vstupnĂ­ hodnotou a ĹĄestimÄsĂ­ÄnĂ­ kontrolou. V tomto ÄlĂĄnku popisujeme design a metodiku studie. ZĂĄsadnĂ­ pro tuto studii je hodnocenĂ­ zmÄn krevnĂ­ho tlaku pomocĂ­ ABPM, nezĂĄvislĂŠ hodnocenĂ­ a uĹžĂ­vĂĄnĂ­ spironolactonu v medikamentĂłznĂ­ lĂŠÄbÄ.
SSF loads and controllability during assembly (1993)

The Orbiter Primary Reaction Control System (PRCS) pulse width and firing frequency is restricted to prevent excessive loads in the Space Station Freedom (SSF). The feasibility of using the SSF Control Moment Gyros (CMG) as a secondary controller for load relief is evaluated. The studies revealed the CMG not only reduced loads but were useful for other SSF functions: vibration suppression and modal excitation. Vibration suppression lowers the g level for the SSF micro-g experiments and damps the low frequency oscillations that cause crew sickness. Modal excitation could be used for the modal identification experiment and health monitoring. The CMG's reduced the peak loads and damped the vibrations. They were found to be an effective multi-purpose ancillary device for SSF operation.
Autoxidation of the indolic neurotoxin 5,6-dihydroxytryptamine (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAutoxidation of the indolic neurotoxin 5,6-dihydroxytryptamineSatendra Singh, Jen Fon Jen, and Glenn DryhurstCite this: J. Org. Chem. 1990, 55, 5, 1484–1489Publication Date (Print):March 1, 1990Publication History Published online1 May 2002Published inissue 1 March 1990https://pubs.acs.org/doi/10.1021/jo00292a020https://doi.org/10.1021/jo00292a020research-articleACS PublicationsRequest reuse permissionsArticle Views96Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts