gebhart/patrepeval huggingface dataset:
Reliable Tabbing Process for Si Thin-Film Solar Cells Using Ultrasonic Bonding (2010)

Tab ribbons are used to conduct current from Si thin-film solar cells to the junction box, where a reliable connection with low contact resistance is required. Ultrasonic bonding is a room-temperature process that can create stronger and more reliable bonds with lower contact resistance at a lower consumable cost. Two types of ribbons (Al ribbon and Al-clad Cu ribbon) with different sizes were ultrasonically bonded on four different Si thinfilm solar panels. The cell structure, metallization layer, and surface conditions and their influence on the ultrasonic bonds were investigated. The process parameters and several bondtool configurations were systematically studied. Bond quality was evaluated mechanically by a 90° bond peel test and electrically by measuring contact resistance. Potential cell damage was inspected by microscope and monitored by measuring the open circuit voltage (Voc) and short circuit current (Isc) of the panel. Robust, reliable bonds were demonstrated by 800 temperature cycles, 1000 hours damp heat, and accelerated lifetime tests. A 16-month accelerated lifetime test showed that the modules with ultrasonically-bonded tab ribbons passed four combined cycles, while four other commercial thin-film modules failed within 1.5 combined cycles.
TMOD-14. INNOVATIVE 3D MODEL FOR THE ESTABLISHMENT OF PRIMARY PAEDIATRIC LOW-GRADE GLIOMA (LGG) CULTURES: NEW PLATFORM FOR ADVANCED PRECLINICAL STUDIES OF INNOVATIVE AND IMMUNOTHERAPEUTIC APPROACHES (2019)

Solid tumours are characterized by a high structural complexity that is difficult to reproduce with common bidimensional (2D) systems. We developed an innovative fibrin-based hydrogel 3D model and tested it as platform to establish primary LGG cultures, otherwise difficult to maintain owing to the activation of senescence pathways. To date, 37 samples were cultured in both 2D and 3D platforms (19 astrocytomas and 18 gangliogliomas), with an average culture duration of 177+13 days, showing that the 3D-culture enables the stabilization of LGG. Whereas in the 2D-culture the cells showed overtime a significant reduction in the average culture days between each passage (average P1-P3:35+6 days; P3-P6: 29+5; >P6: 17+5), suggesting the selection of a peculiar clone, in the 3D-setting, we observed a more regular growth (average P1-P3:44+5 days; P3-P6: 64+20;>P6: 48+16). Cell lines identity was confirmed by short tandem repeats (STRs) and the immunohistochemical characterization (H&E, Ki67, tumour and differentiation markers) in 3D cultures revealed phenotype, cellular organization and proliferative rates closer to those observed in the onset samples, as compared to the 2D. We then analyzed the methylation profile and preliminary results suggest that the 2D lines evolve towards different lineages. The analysis of cell senescence using ß-galactosidase assay revealed a lower senescence in the 3D cultures (3D:12,28%+4,3% of the cells vs 2D:50,69%+18,46%; p=0,008). Lastly, we evaluated the responses to radiotherapy by MTS assay, and showed that 2D-cultured cells are more sensitive to treatment than 3D (2D: untreated, 0,0232+0,023, 160 Gy 0,089+0,025; 3D: untreated 0,235+0,09, 160 Gy 0,169+0,08), suggesting an overestimation of the efficacy of such treatment by the 2D-setting, therefore reducing the predictive power. The response to chemotherapy and more innovative approaches (i.e. Oncolytic Adenovirus) is currently under evaluation, the preliminary results confirming a similar finding. Overall, the 3D-culture offers an innovative platform for biological and therapeutic studies.
Strain‐induced fetal type II epithelial cell differentiation is mediated via cAMP‐PKA‐dependent signaling pathway (2006)

The signaling pathways by which mechanical forces modulate fetal lung development remain largely unknown. In the present study, we tested the hypothesis that strain‐induced fetal type II cell differentiation is mediated via cAMP signaling pathway. Freshly isolated E19 fetal type II epithelial cells were cultured on collagen‐coated silastic membranes and exposed to mechanical strain for varying intervals, to simulate mechanical forces in utero. Unstretched samples were used as controls. Mechanical strain activated heterotrimeric G‐protein α s subunit, cAMP and the transcription factor CREB. Moreover, adenylate cyclase 5 and CREB genes were also mechanically induced. In contrast, components of the PKA‐independent (Epac) pathway, including Rap‐1 or B‐Raf, were not phosphorylated by strain. The addition of forskolin to unstretched E19 monolayers markedly upregulated expression of the type II cell differentiation marker surfactant protein‐C (SP‐C), whereas the Epac agonist 8‐pCPT‐2′‐O‐Me‐cAMP had no effect. Incubation of E19 cells with PKA inhibitors significantly decreased strain‐induced CREB phosphorylation and SP‐C mRNA expression. In conclusion, these studies indicate that cAMP‐PKA‐dependent signaling pathway is activated by force in fetal type II cells and participates in strain‐induced fetal type II cell differentiation. This work was supported by National Institutes of Health Grants RR‐018728 and Parker B. Francis.
TSPO: functions and applications of a mitochondrial stress response pathway (2015)

The mitochondrial outer membrane protein TSPO (translocator protein) lies in a privileged position at the interface between mitochondrion and cytosol. Since the initially discovery, nearly forty years ago, it has generated major interest among various disciplines of modern experimental and applied biomedicine. The focused meeting we have organized aimed at summarizing the state of the art knowledge on TSPO and the discipline-based segregated concepts that have made this an exciting and active field of science. The scientists who have generously contributed the event have agreed to generate a special issue here published--stemmed from the discussion of the vent. This consists in a series of contributions via which the know-how is shared aiming to inspire current and future endeavours to validate and accelerate the impact of TSPO science in human pathophysiology and clinical applications.
Close relationship of RNase P RNA in Gemmata and anammox planctomycete bacteria (2007)

The relationship of RNase P RNA from anammox bacteria 'Candidatus Brocadia anammoxidans' and 'Candidatus Kuenenia stuttgartiensis' with that from other Planctomycetes was investigated. Newly identified rnpB gene sequences were aligned against existing planctomycete RNase P RNA sequences and secondary structures deduced by a comparative approach. Deduced secondary structures were similar in both anammox bacteria and both possessed an insert within the P13 helix analogous to that present in all Gemmata isolates. Phylogenetic analysis also revealed a possible relationship between the RNase P RNA molecules of the two anammox organisms and the genus Gemmata.
Energy Savings Using Wake-Up Receivers - An Analysis of Optimal Designs (2019)

With increasing number of wirelessly connected devices having limited energy resources, energy efficient solutions become more and more important. Many studies have addressed schemes where low-power wake-up receivers are used to improve energy efficiency in networks with low traffic intensity (per node) and demands on availability. One such scheme is the duty-cycled wake-up receiver medium access (DCW-MAC) scheme, for which we have detailed understanding of achievable energy savings. In this paper we combine these with recent bounds on the characteristics of optimal low-power receiver designs. What we find is that network energy savings are always achievable with optimally designed wake-up receivers. Moreover, potential network energy savings increase as wake-up receiver power consumption decreases, despite the associated degradation in performance. The lowest network energy consumption, for this type of network, is reached for wake-up receivers pushed to the limit of functioning.
The discriminatory power of MALDI-TOF mass spectrometry to differentiate between isogenic teicoplanin-susceptible and teicoplanin-resistant strains of methicillin-resistantStaphylococcus aureus (2006)

To explore the discriminatory power of matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) for detecting subtle differences in isogenic isolates, we tested isogenic strains of Staphylococcus aureus differing in their expression of resistance to methicillin or teicoplanin. More important changes in MALDI-TOF MS spectra were found with strains differing in methicillin than in teicoplanin resistance. In comparison, very minor or no changes were recorded in pulsed-field gel electrophoresis profiles or peptidoglycan muropeptide digest patterns of these strains, respectively. MALDI-TOF MS might be useful to detect subtle strain-specific differences in ionizable components released from bacterial surfaces and not from their peptidoglycan network.
Towards Federated Learning at Scale: System Design (2019)

Federated Learning is a distributed machine learning approach which enables model training on a large corpus of decentralized data. We have built a scalable production system for Federated Learning in the domain of mobile devices, based on TensorFlow. In this paper, we describe the resulting high-level design, sketch some of the challenges and their solutions, and touch upon the open problems and future directions.
Mimo Generalized Decorrelating Discrete-Time Rake Receiver (2005)

Publication in the conference proceedings of EUSIPCO, Antalya, Turkey, 2005
Heart rate variability -based recovery during sleep compared to movement analysis,subjective ratings and cortisol awakening responses (2006)

unknown accessibility
Effect of deoxyguanosine on lymphopoiesis in the developing thymus rudiment in vitro: Application in the production of chimeric thymus rudiments (1982)

On the basis of reports that deoxyguanosine is selectively toxic for adult T lymphocytes, the usefulness of this compound in the production of lymphocyte-depleted embryonic thymus rudiments in an in vitro organ culture system was investigated. The results showed that a period of exposure to deoxyguanosine causes depletion of the lymphoid cells while the stromal elements continue to survive, with many of the cells showing an epithelial morphology and expression of I region products of the major histocompatibility complex (MHC). When associated with either fetal liver or another thymus fragment as a source of T cell precursors in transfilter experiments, these "empty" thymuses become recolonized, enabling the production of chimeric thymus with stromal and lymphoid cells of different haplotypes. In combination with functional assays, this system offers an entirely in vitro approach to questions relating to the repertoire potential of T cell precursors from different sources and the role of the thymus in tolerance and MHC restriction.
Tuning the composition of conductive thermoplastics for stiffness switching and electrically activated healing (2019)

We introduce a class of stiffness-tuning polymer composites and carefully examine the influence of electrical activation and temperature on stiffness for a wide range of use cases. The composites are composed of a polycaprolactone matrix embedded with a percolating network of acetylene carbon black or multi-walled carbon nanotubes. This work builds on previous efforts with thermally activated stiffness-switching composites, which can enable reliable, high-switching-ratio stiffness-switching devices that are stiff in the passive state and are not confined to specific geometries or layouts. Here, we systematically investigate the effects of filler type, filler concentration, and matrix polymer molecular weight on the critical properties of the stiffness-switching material. Using these parameters, we develop a composition selection guide, which we use to construct three different stiffness-switching applications: a highly extensible stiffness-switching tendon, a large area moldable sheet, and an electrically healable mechanical fuse.
Investigation of the Therapeutic Potential of FES in Improving Hand Function in Children with Cerebral Palsy (1992)

42 5.1.3Ground Electrode Size 44 5.1.4Stimulator 45 5.1.5Simulator Variable Settings 47 5.2 CP Subjects Involved with this Research 54 5.2.1 Medical History 54 5.3 D.S. 56 5.3.1 Treatment 57 5.3.2Measurements 61 5.4 C.R. 66 5.4.1 Treatment 66 5.4.2Measurements 69 5.5 M.E.71 5.5.1 Treatment 71 5.5.2Measurements 72 VI.Data 74 6.1 Display Methods 74 6.2 D.S. 76 6.2.1 Range of Motion 76 6.2.2 Grip and Pinch Strengths 78 6.2.3 Dexterity Tests 80 6.3 C.R. 94 6.3.1 Range of Motion 94 6.3.2Grip and Pinch Strengths 98 6.3.3Dexterity Tests 101 6.4
Location of Lignin-Bonded Pectic Polysaccharides (1991)

Abstract The hypothesis that galactose and arabinose pectic substances are disributed with lignin throughout wood cell walls was tested by analyzing a high-yield loblolly pine kraft pulp that had been separated into middle-lamella-rich and secondary-wall-rich fractions. The fractions were first treated with a polysaccharidase enzyme mixture to obtain "enzyme lignins." The structures of the galactose and arabinose oligomers remaining attached to the lignin were determined by methylation analysis. The 1→4 linked galactose structure, characteristic of pectic materials, was present in significant amounts in the middle-lamella-rich fraction, but to only a very small extent in the secondary-wall-rich fraction. In contrast, the pectic arabinan 1→5 linked structure was a significant proportion of the arabinose from both fractions. The 1→5 linked arabinose structure can arise from a linkage of arabinoxylan to lignin through the 5 position of the arabinose substituent as well as from pectic structures. After partial acid hydrolysis, approximately half the remaining arabinose in the secondary-wall-rich fraction was attached as monomeric units to lignin through the 5 position.
Targeted Elimination of Tumorigenic Human Pluripotent Stem Cells Using Suicide-Inducing Virus-like Particles (2018)

Sensitization to prodrugs via transgenic expression of suicide genes is a leading strategy for the selective elimination of potentially tumorigenic human pluripotent stem cells (hPSCs) in regenerative medicine, but transgenic modification poses safety risks such as deleterious mutagenesis. We describe here an alternative method of delivering suicide-inducing molecules explicitly to hPSCs using virus-like particles (VLPs) and demonstrate its use in eliminating undifferentiated hPSCs in vitro. VLPs were engineered from Qβ bacteriophage capsids to contain enhanced green fluorescent protein (EGFP) or cytosine deaminase (CD) and to simultaneously display multiple IgG-binding ZZ domains. After labeling with antibodies against the hPSC-specific surface glycan SSEA-5, EGFP-containing particles were shown to specifically bind undifferentiated cells in culture, and CD-containing particles were able to eliminate undifferentiated hPSCs with virtually no cytotoxicity to differentiated cells upon treatment with the prodrug 5-fluorocytosine.
Comparison of the Three Algorithms for Concreteness Rating Estimation of English Words (2022)

The paper compares three algorithms for concreteness rating estimation of English words.To train and test the models, we used a number of freely available dictionaries containing concreteness ratings.A feedforward neural network is employed as a regression model.Pre-trained fastText vectors, data on co-occurrence of target words with the most frequent ones, and data on co-occurrence of target words with functional words are used as input data by the considered algorithms.One of the three algorithms was proposed for the first time in this article.We provide detailed explanations of which combinations with functional words are the most informative in terms of concreteness ratings estimation for English words.Although the rest two algorithms have already been used for estimation of concreteness ratings, we consider possible ways to update them and improve the results obtained by a neural network.Thuswise, we use stochastic Spearman's correlation coefficient as a criterion for stopping of training.All three algorithms provided good results.The best value of Spearman's correlation coefficient between the value of the concreteness rating and its estimate was 0.906, which exceeds the values achieved in previous works.
An object-oriented methodology for knowledge base/database coupling (1992)

article Free Access Share on An object-oriented methodology for knowledge base/database coupling Authors: Kunihiko Higa Georgia Institute of Technology, Atlanta Georgia Institute of Technology, AtlantaView Profile , Mike Morrison Univ. of Arizona, Tucson Univ. of Arizona, TucsonView Profile , Joline Morrison Univ. of Arizona, Tucson Univ. of Arizona, TucsonView Profile , Olivia R. Liu Sheng Univ. of Arizona, Tucson Univ. of Arizona, TucsonView Profile Authors Info & Claims Communications of the ACMVolume 35Issue 6June 1992pp 99–113https://doi.org/10.1145/129888.129895Published:01 June 1992Publication History 18citation715DownloadsMetricsTotal Citations18Total Downloads715Last 12 Months31Last 6 weeks9 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Structure of complexes between bromine trifluoride and Lewis acids (1970)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructure of complexes between bromine trifluoride and Lewis acidsKarl O. Christe and Carl J. SchackCite this: Inorg. Chem. 1970, 9, 10, 2296–2299Publication Date (Print):October 1, 1970Publication History Published online1 May 2002Published inissue 1 October 1970https://pubs.acs.org/doi/10.1021/ic50092a018https://doi.org/10.1021/ic50092a018research-articleACS PublicationsRequest reuse permissionsArticle Views119Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Clinical efficacy of the acyclic nucleoside phosphonate 9-(2-phosphonylmethoxypropyl)-2,6-diaminopurine (PMPDAP) in the treatment of feline immunodeficiency virus-infected cats (2012)

In in vitro studies, the acyclic nucleoside phosphonate 9-(2-phosphonylmethoxypropyl)-2,6-diaminopurine (PMPDAP) inhibited the replication of feline immunodeficiency virus (FIV). No information about its clinical efficacy is available so far. The aim of this prospective placebo-controlled, double-blinded study was to evaluate the antiviral efficacy of PMPDAP in cats naturally infected with FIV. Twenty cats were randomly assigned to two treatment groups receiving either PMPDAP (25 mg/kg) or placebo twice per week subcutaneously for 6 weeks. The general health status (Karnofsky's score), clinical signs, laboratory, immunological, and surrogate parameters were evaluated. No significant differences were found between PMPDAP- and placebo-treated cats, although cats treated with PMPDAP showed a tendency for improvement in their Karnofsky's score and clinical signs. Haematological side effects were noted in the PMPDAP-treated cats. Thus, PMPDAP may be an option in treating cats if it becomes available for veterinarians, but side effects have been monitored.
Fourier-transform pulse shaping using a single chirped fiber Bragg grating (2009)

A Fourier-transform pulse shaper using a single linearly chirped fiber Bragg grating (LCFBG) is proposed and investigated. The LCFBG in the system performs three functions: temporally stretching the input pulse, shaping the pulse spectrum, and compressing the spectrum-shaped pulse. The impulse response of the entire system is equal to the Fourier transform of grating reflection spectral function. By appropriately designing the grating reflection response, a temporal optical waveform in the sub-picosecond regime can be accurately synthesized.
ChemInform Abstract: An Efficient Synthesis of Methyl Esters of Heterocyclic α,β‐Didehydro‐α‐amino Acid Derivatives. (2011)

Abstract A simple and general method for the selective esterification of the title amino acids without destruction of the C=C bond is presented.
Pumps (2000)

Abstract Pumps are used in a wide range of industrial applications in the chemical processing industries. Pumping equipment varies widely in terms of pump type, size, and materials of construction. The two principal pump types, kinetic, which is mainly centrifugal, and positive displacement, are presented and basic operating parameters such as capacity, head, power, efficiency, and specific speed are defined. Fundamentals of operation are discussed, selection guidelines given, and examples of pump applications and reliability concerns provided. Pump auxiliaries such as couplings and seals, as well as effects of cavitation, recirculation, internal hydraulic forces, wear, and corrosion, are described. Cost approximation methodology is presented along with a list of manufacturers.
Model selection in meta-analytical framework for prototype-based clustering (2007)

THE microarray technology allows biologists and doctors to measure the expression of severalthousand of genes in parallel. Each microarray chip uses up to 50,000 probes to measure these expressions, generating a huge amount of data to analyze. The high cost of microarray experiments and the coexistence of different microarray technologies make difficult the generation of datasets with large number of samples. In addition to the high feature-to-sample ratio, these data are characterized
Important food sources of fructose-containing sugars and adiposity: A systematic review and meta-analysis of controlled feeding trials (2023)

Energy control and food sources mediate the effect of fructose-containing sugars on adiposity. The evidence provides a good indication that excess energy from sugars (particularly SSBs at high doses ≥20%E or 100 g/d) increase adiposity, whereas their removal decrease adiposity. Most other food sources had no effect, with some showing decreases (particularly fruits at lower doses ≤10%E or 50 g/d). This trial was registered at clinicaltrials.gov as NCT02558920 (https://clinicaltrials.gov/ct2/show/NCT02558920).