gebhart/patrepeval huggingface dataset:
A Prospective Study of Surgically Treated Acetabular Fractures (1994)

Between November 1988 and March 1993, 101 patients with 102 fractures of the acetabulum were referred to the authors' institution. They included 31 both column; 25 transverse associated posterior wall; 16 anterior column associated posterior hemitransverse; 9 posterior wall; 7 posterior column associated posterior wall; 7 anterior column; 5 T shaped; and 2 transverse fractures. Thirteen fractures were excluded, leaving 89 patients with 89 operatively treated fractures available for followup. Postoperative radiographs were evaluated for adequacy of reduction and scored on a scale of 1-9 with 9 being perfect. Perfect or near perfect reduction was achieved in 82% of patients. A minimum of 1 year followup was available for 53 patients. Clinical results were assessed in terms of the patients' activities and included their ability to walk, range of motion and pain. Excellent results were achieved in 27 patients and an additional 16 had satisfactory results, for an overall 81% acceptable outcome. Radiographic evidence of posttraumatic osteoarthrosis was present in 40% of patients: mild in 10, moderate in 5, and severe in 5. Heterotopic ossification was Brooker Grade III and Grade IV in 1 patient each. These results indicate that operative treatment of acetabular fractures provides results that are superior to those achieved with nonoperative treatment.
Cloud Testing for Mobile Software Systems - Concept and Prototyping (2013)

This paper describes an approach for increasing the effectiveness of mobile software system testing. A Cloud Testing of Mobile Systems (CTOMS) framework is presented in the form of a cloud service that provides the ability to run tests on a variety of remote mobile devices. This framework is based on a heterogeneous networked system that connects operational computers, mobile devices, and databases with software applications. Our research focuses on building a concept and a prototype of CTOMS that supports testing Android mobile applications in the cloud. CTOMS allows multidirectional testing, providing the opportunities to test an application on different devices and/or operating system (OS) versions and new device models for their compatibility with the newest OS versions and the most popular applications. Another new aspect is to embed the test model, specifically the appropriate testing techniques for mobile development, within the framework. For users, this model will provide suggestions from CTOMS about the test methods, criteria, coverage, and possible test cases. These suggestions are based on available configurations, statistics, and resource constraints.
Association of proton pump inhibitors with survival in Veterans with non-small cell lung cancer receiving immunotherapy. (2021)

e18729 Background: Proton pump inhibitors (PPI) can disrupt the gut microbiome and thereby modulate response to immunotherapy in cancer patients. In a recently published post-hoc analysis of 757 non-small cell lung cancer (NSCLC) patients receiving atezolizumab pooled from two prospective trials, overall survival (OS) and progression-free survival were significantly lower among the 234 patients receiving PPI. We investigated the impact of PPI in a larger cohort of NSCLC patients treated with ICI within the Veterans Health Administration. Methods: We conducted a nested cohort study of Veterans who were diagnosed with NSCLC between 2010 &amp; 2018 and treated with ICI (immune checkpoint inhibitors). Exposure was defined as receipt of a PPI prescription within 90 days of an ICI infusion. Chi-square tests were used to compare characteristics of exposed versus unexposed Veterans. OS was measured from start of ICI. Cox proportional hazard multivariate (MV) regression was used to calculate hazard ratios (HR) corresponding to variables associated with OS. Results: We identified 3,634 Veterans receiving ICI with non-exclusive exposures to nivolumab (59.3%), pembrolizumab (35.1%), durvalumab (6.9%), and atezolizumab (3.3%). Their median age was 69, and a plurality had male gender (97.0%), white race (73.0%), comorbidity count ≥1 (60.4%), adenocarcinoma (47.8%), and stage IV disease at diagnosis (40.9%). In this nested cohort, 2,159 (59.4%) were exposed to PPI, predominantly omeprazole (1,264 or 85.6% of PPI group). Patients receiving PPI were more likely to be ≤71 years of age, to be white, to reside in rural areas, to have a higher comorbidity burden, to have adenocarcinoma histology, and to receive chemotherapy (all p≤0.04). On MV analysis, PPI use was not significantly associated with detriment in OS (HR 0.96 [0.89-1.04], p= 0.35). In the matched cohort analysis, median survival did not significantly differ between the 1,389 patients taking PPI and the 1,389 without PPI (median 10 versus 10 months, HR 0.98 [0.90-1.06], p= 0.59). Conclusions: In the largest analysis to date of concurrent PPI use in patients with NSCLC receiving ICI, there were no survival differences associated with concomitant PPI use. These results suggest that PPIs do not compromise ICI efficacy.
Particle-image velocimetry measurement errors when imaging through a transparent engine cylinder (2002)

When making particle-image velocimetry measurements through the quartz cylinder of a reciprocating engine, the particle images are aberrated. This work quantifies the practical field-of-view and the errors in the velocity measurements caused by those aberrations. Electro-optical image shifting was used to create a repeatable particle-image displacement distribution for 60 images. Ensemble averaging of these images is used to quantify the rms errors due to the shot-to-shot variation in (1) the particle-image fields, (2) the camera noise, (3) the variance in the correlation-peak detection and (4) the particle-image aberrations. These results demonstrate that the field-of-view is restricted to the centre 66 mm of the 86 mm inside-diameter cylinder due to decreased accuracy, decreased image-to-image precision and decreased displacement-peak detectability of the image-displacement correlation. The correlation-peak detectability was degraded by both particle-image aberrations and decreased transmission of the scattered light.
Forward error correcting for CDMA systems (2002)

Spread spectrum systems especially code division multiple access systems (CDMA) match very well with channel coding employing forward error correcting (FEC) methods. We will cover in this overview article some aspects of FEC channel coding in CDMA systems: CDMA/FEC systems can be viewed as concatenated schemes with inner and outer decoding. We will show how such a system can be improved by using a soft-in/soft-out decoder which transfers a soft decision from the inner to the outer decoder. Further improvement is gained by using another soft-in/soft-out decoder for the outer code. In an iteration the soft values of the outer code bits are then used as a priori values for the inner CDMA decoder/despreader. This can he supplemented by soft decoded bits from the other users' outer decoder similar to an interference cancellation scheme. Applications to the IS 95 system with Hadamard codes show a remarkable gain from the soft-output and from the iterations. 'Turbo' decoding of two and more dimensional product-like codes with iterative decoding using 'soft-in/soft-out' decoders achieves almost channel capacity. We extend this concept to CDMA systems with PN spreading sequences where FEC coding in one dimension is performed in the time direction and FEC coding in the other dimension is performed by a systematic code in the CDMA code direction. The parity bits of this code are transmitted by extra CDMA codes. The additional interference degradation caused hereby is outweighted by the extra FEC coding gain achieved by iterative decoding.
Adaptive optical beam steering and tuning system based on electrowetting driven fluidic rotor (2020)

Abstract Reconfigurable beam steering components are indispensable to support optical and photonic network systems operating with high adaptability and with various functions. Currently, almost all such components are made of solid parts whose structures are rigid, and hence their functions are difficult to be reconfigured. Also, optical concentration beam steering is still a very challenging problem compared to radio frequency/microwave steering. Here we show a watermill-like beam steering system that can adaptively guide concentrating optical beam to targeted receivers. The system comprises a liquid droplet actuation mechanism based on electrowetting-on-dielectric, a superlattice-structured rotation hub, and an enhanced optical reflecting membrane. The specular reflector can be adaptively tuned within the lateral orientation of 360°, and the steering speed can reach ~353.5° s −1 . This work demonstrates the feasibility of driving a macro-size solid structure with liquid microdroplets, opening a new avenue for developing reconfigurable components such as optical switches in next-generation sensor networks.
Multimedia edges: finding hierarchy in all dimensions (2001)

This paper describes a new unified representation for the information in a video. We reduce the dimensionality of the signal with either a singular-value decomposition (on the semantic and image data) or mel-frequency cepstral coefficients (on the audio data) and then concatenate the vectors to form a multi-dimensional representation of the video. Using scale-space techniques we find large jumps in the video's path, which we call edges. We use these techniques to analyze the temporal properties of the audio and image data in a video. This analysis creates a hierarchical segmentation of the video, or a table-of-contents, from the audio, semantic and image data.
EUR-ACE accreditation for chemical engineering in Spain: Current situation, lessons learned and challenges (2023)

The accreditation of engineering programmes is a subject of great interest in the last decades. However, most studies in the literature are focused on case studies or deal with the different levels of acceptance of the groups involved in the accreditation. There are two main approaches for the accreditation of engineering programmes, i.e., at national or international level. Whereas most developed countries have established national standards for the quality assurance of the university studies, international accreditation systems for engineering studies are limited to 3 alternatives. The interaction between national and international accreditation systems is poorly understood despite of their significance in the design and management of the programme. We aim to fill in this gap and provide useful guidance for universities aiming to apply for the EUR-ACE® label in their chemical engineering programmes (bachelor or master). In general, there is a high level of complementarity between the Spanish and EUR-ACE accreditation systems. However, there are still challenges. For instance, the ad hoc procedure proposed by the national accreditation agency in Spain does not fully consider chemical engineering as a traditional branch of engineering. In addition, the changes in the Spanish accreditation system might negatively impact the current ad hoc procedure for EUR-ACE accreditation for some universities. The incorporation of IChemE in the accreditation process would be an option to deal with this issue.
Detection of the Proto-oncogene eIF4E in Larynx and Hypopharynx Cancers (1999)

eIF4E in the surgical margins is an independent prognostic factor and its absence in surgical margins may predict long-term survival. Detecting eIF4E in the margins may improve survival by determining which patients would benefit from further resection or adjuvant therapy.
ANALYSIS AND COMPARISON OF SOME AUTOMATIC VEHICLE MONITORING SYSTEMS (1973)

In 1970 UMTA solicited proposals and selected four companies to develop systems to demonstrate the feasibility of different automatic vehicle monitoring techniques. The demonstrations culminated in experiments in Philadelphia to assess the performance capabilities of each system. The purpose of the report is to analyze and compare those different AVM systems and to answer some specific questions that appear on the FCC Docket No. 18302. These questions are on the performance comparisons of the AVM systems with respect to accuracy, bandwidth, update rate, and data transmission capability. In addition some general considerations on the different AVM systems have been made with respect to performance. (Author)\n
Manganese Doping in Cobalt Oxide Nanorods Promotes Catalytic Dehydrogenation (2020)

Heteroatom doping in nanomaterials can import new active sites and promote catalytic activity. Here we report that Mn-doped Co3O4 nanorods (Mnx-Co3O4) via substituting Mn3+ (t2g3-eg1) for Co3+ (t2g6-eg0) exhibit ∼100% yield for 4-methyl benzyl alcohol dehydrogenation catalysis at 60 °C and no decay (8 cycles), compared with only 1.4% of activity for bare Co3O4 catalysts. We characterize the fine structures of Mnx-Co3O4 at the atomic level and demonstrate that the superior catalytic performance is strongly related to the Mn3+-induced Jahn–Teller (J–T) effect, which is a geometric distortion that has generally been considered to be disadvantageous for applications. Experimental observations and theoretical calculations reveal that unsaturated Mn3+ with J–T distortion acts as an active site, and readily reacts with −OH groups of benzyl alcohol adsorbed nearby, simultaneously promoting dehydrogenation to directly yield benzaldehyde. Mnx-Co3O4 catalysts rapidly dehydrogenate alcohols into aldehydes/ketones for 19 reactions with >99.9% selectivity and 14 examples with >90.2% yield.
Clonal analysis of the relationship between class II MHC-restricted cytolysis and lymphokine secretion in murine L3T4+ T cells. (1991)

A panel of peptide-specific murine CD4+ T-cell clones was tested for lymphokine secretion, antigen-specific cytolysis and CD3-mediated cytolysis. The data indicated an imperfect correlation between Th1/Th2 status with regard to antigen-specific cytolysis but also indicated that all the clones were cytotoxic when stimulated with anti-CD3 antibody.
Removal of Vegetative Clippings Reduces Dissolved Phosphorus Loss in Runoff (2014)

Rainfall simulation was used to study the vegetative filter strip (VFS) conditions under which losses of total dissolved phosphorus (TDP) and dissolved reactive phosphorus (DRP) leaching occur. Boxes containing silt loam soil were planted with ryegrass and cut at two different intervals prior to simulated rainfall 14 days apart. Grass clippings were either removed or retained. During the second simulated rainfall, runoff TDP and DRP were greater for treatments cut the day before irrigation with clippings retained as compared to treatments cut the same day as irrigation with clippings retained. Removing clippings yielded the lowest mean TDP and DRP concentrations. Increasing the senesced vegetative surface area for contact with water, and the amount of time for leaching to occur, resulted in the greatest DRP loss. The VFS management implications should consider clipping removal or no or reduced mowing during the growing season followed by end-of-season removal to reduce DRP leaching losses.
HORMONAL AND NEURONAL PEPTIDES AND BEHAVIOR (1983)

Journal Article Hormonal and Neuronal Peptides and Behavior Get access D de Wied D de Wied Rudolf Magnus Institute for Pharmacology, Medical Faculty University of Utrecht, Vondellaan 6, 3521 GD Utrecht, The Netherlands Search for other works by this author on: Oxford Academic Google Scholar Acta Endocrinologica (Norway), Volume 104, Issue 2_Supplement_b, Aug 1983, Pages S20–S25, https://doi.org/10.1530/acta.0.103S020 Published: 01 August 1983
Poly(I:C)/Alum Mixed Adjuvant Priming Enhances HBV Subunit Vaccine-Induced Immunity in Mice When Combined with Recombinant Adenoviral-Based HBV Vaccine Boosting (2013)

The protein-vaccine HBSS1 with mixed poly(I:C)/alum adjuvant priming, followed by a rAdSS1 vaccine boost, maximises specific antibody and Th1-biased cellular immune responses. This regime might prove useful in the development of HBV therapeutic vaccines. Furthermore, this promising strategy might be applied to vaccines against other persistent infections, such as human immunodeficiency virus and tuberculosis.
Introduction of a Prognostic Decision Making in a Fault Tolerant Control Context (2018)

The paper deals with the design of an enhanced active Fault Tolerant Control (FTC) scheme based on the concept of supervisory control for uncertain Linear Time Invariant (LTI) systems. The improvement lies on the introduction of a Prognostic Decision Making (PDM) unit and a Virtual Fault Mechanism (VFM) in the supervisory FTC setup. The main purpose is to forecast the switching control thanks to the fault prediction to better mitigate the reconfiguration transients, while exponential stability is guaranteed by the dwell-time conditions. Since the diagnosis task is maintained in FTC setup to safely react to unforeseeable events, the solution proposes a structure where diagnosis, prognostic and accommodation tasks can work together in harmony. This work is applied to the academic aeronautical benchmark to highlight its potential. Copyright © 2018 IFAC
BestPeer: a self-configurable peer-to-peer system (2003)

We present BestPeer, a prototype P2P system that we have implemented at the National University of Singapore. BestPeer is a generic P2P system designed to serve as a platform on which P2P applications can be developed easily and efficiently. The network consists of two types of entities: a large number of computers (nodes), and a relatively fewer number of location independent global name lookup (LIGLO) servers. Each participating node runs the BestPeer (Java-based) software and will be able to communicate or share resources with any other nodes (i.e., peers) in the BestPeer network. Each node comprises two types of data: private data and sharable data. Nodes can only access peers' data that are sharable.
Abstract 13193: Prevalence of Late Gadolinium Enhancement Following Pediatric Heart Transplantation Increases With Time Since Transplantation (2022)

Introduction: Chronic graft failure in pediatric heart transplant recipients (PHT) is associated with myocardial fibrosis on explanted specimens. Cardiac magnetic resonance imaging (CMR) is a validated, non-invasive method to detect myocardial fibrosis via the presence of late-gadolinium enhancement (LGE). In adult heart transplant recipients, LGE is associated with increased risk of hospitalization and death. We describe LGE on CMR among PHT and its associations with clinical and graft characteristics. Methods: We performed a retrospective chart review of all PHT who underwent CMR over a 6-year period at a single center (81 CMR studies, 59 unique patients). Two independent reviewers assessed the presence and distribution of LGE using the AHA 17-segment model. Clinical history and CMR-derived volumetry/ejection fraction were obtained; differences between LGE+ and LGE- PHT were evaluated. Results: Mean age at CMR was 14.8±4.6y; mean time since transplant was 7.3±5.0y. CMR indication was routine surveillance (without active rejection or history of cardiac allograft vasculopathy) in 63% (51/81) of studies. LGE was present in 36% (29/81). LGE patterns included: posterior hinge-point 27% (22/81), lateral wall 15% (12/81), and extensive, involving &gt;4 AHA segments, 7% (6/81) (Figure). Reviewing initial CMR per PHT (n=59), LGE+ patients were older (17 vs. 13y; p=0.001), with greater time since transplant (8.3 vs. 5.7y; p= 0.041). They demonstrated increased indexed LV end-systolic volume (35 vs. 29 ml/m2; p=0.011) and decreased LV ejection fraction (56.2 vs 60.6%; p=0.015). There were no significant differences in history of moderate/severe rejection or cardiac allograft vasculopathy. Conclusions: LV LGE was seen in about a third of PHT patients, more commonly in older patients with longer time since transplantation. Grafts with LGE show remodeling with lower LV ejection fraction. CMR-derived LGE may improve surveillance of chronic graft failure in PHT.
Endogenous Gibberellins of Pine Pollen (1976)

Gibberellins A(1) and A(34) (possibly A(2)) were found as products of metabolism of 1,2-[(3)H]GA(4) during germination of Pinus attenuata pollen. The conversion from GA(4) to GA(1) and GA(34) occurred as hydroxylations at atoms C-13 and C-2 of the ent-gibberellane skeleton, respectively. Percentage interconversion of the GA(4) absorbed was in the range of 0.15 to 0.43% for GA(1) and 1.54 to 3.22% for GA(34). Identifications were made on a gas-liquid chromatograph with radioactive monitoring by comparison with standards.
Delay estimation in the presence of a tone jammer: two simple estimators (2003)

Two delay estimators that mitigate the effects of a tone jammer are presented. They are based on the phase interference extractor (PIE) and auxiliary-vector (AV) data detection principles. The estimators are analyzed by computer simulations and shown to tolerate more powerful jammers than the conventional correlator estimator does.
Intestinal villous M cells: An antigen entry site in the mucosal epithelium (2004)

M cells located in the follicle-associated epithelium of Peyer's patches (PP) are shown to be the principal sites for the sampling of gut luminal antigens. Thus, PP have long been considered the gatekeepers of the mucosal immune system. Here, we report a distinct gateway for the uptake of gut bacteria: clusters of non-follicle-associated epithelium-associated Ulex europaeus agglutinin (UEA)-1(+) cells, which we have designated intestinal villous M cells. Interestingly, villous M cells are developed in various PP [or gut-associated lymphoid tissue (GALT)]-null mice, such as in utero lymphotoxin beta receptor (LTbetaR)-Ig-treated, lymphotoxin alpha (LTalpha)(-/-), tumor necrosis factor/LTalpha(-/-), and inhibition of differentiation 2 (Id2)(-/-) mice. Intestinal villous M cells have been observed to take up GFP-expressing Salmonella, Yersinia, and Escherichia coli-expressing invasin, as well as gut bacterial antigen for subsequent induction of antigen-specific immune responses. Thus, the identified villous M cells could be an alternative and PP-independent gateway for the induction of antigen-specific immune responses by means of the mucosal compartment.
Understanding the Diffractive Bifocal Contact Lens (1993)

How a diffractive bifocal contact lens works is not intuitively obvious. This is because the diffractive bifocal operates by an unusual blend of refraction and interference. The present article seeks to clarify how it achieves its two focal powers. Most of this article, however, is devoted to the conceptually simpler case of diffraction gratings in order to develop an intuition for how a double focus is produced. Single slit, double slit, and multiple slit gratings are considered using two formalisms: Feynman's "arrow" method (also called phasors) and the Fourier method. When dealing with linear diffraction gratings we are interested in the light intensity in the focal plane. By a simple redefinition of variables, all of the mathematics for diffraction gratings can be applied to circular lenses. For this latter case instead of looking at the light intensity in the focal plane, we look at light intensity on the optic axis. The appearance of two focal points is a simple consequence of a combined interference and diffraction pattern. The goal of this article is to present an introduction to Fourier optics and an analysis of the bifocal contact lens in a reader-friendly manner.
Erratum to: Japanese traditional dietary fungus koji Aspergillus oryzae functions as a prebiotic for Blautia coccoides through glycosylceramide: Japanese dietary fungus koji is a new prebiotic (2016)

[This corrects the article DOI: 10.1186/s40064-016-2950-6.].