gebhart/patrepeval huggingface dataset:
Molecular Epidemiology of Group B Streptococcus Colonization in Egyptian Women (2022)

(1) Background: <i>Streptococcus agalactiae</i> or Group B Streptococcus (GBS) causes severe neonatal infections with a high burden of disease, especially in Africa. Maternal vaginal colonization and perinatal transmissions represent the common mode of acquiring the infection. Development of an effective maternal vaccine against GBS relies on molecular surveillance of the maternal GBS population to better understand the global distribution of GBS clones and serotypes. (2) Methods: Here, we present genomic data from a collection of colonizing GBS strains from Ismailia, Egypt that were sequenced and characterized within the global JUNO project. (3) Results: A large proportion of serotype VI, ST14 strains was discovered, a serotype which is rarely found in strain collections from the US and Europe and typically not included in the current vaccine formulations. (4) Conclusions: The molecular epidemiology of these strains clearly points to the African origin with the detection of several sequence types (STs) that have only been observed in Africa. Our data underline the importance of continuous molecular surveillance of the GBS population for future vaccine implementations.
Parameterization of IR cooling in a middle atmosphere dynamics model: 1. Effects on the zonally averaged circulation (1982)

A computationally efficient two‐stream parameterization of IR cooling is developed for a middle atmosphere dynamics model. The parameterization combines the monochromatic feature of an emissivity formulation with the computational simplicity of a single spatial integral to evaluate the monochromatic transfer equation. Our calculations show strong radiative control of the mesopause region (radiative relaxation rate &gt; [5 days] −1 ) and the need for substantial deceleration of the mean zonal winds (∼40 m s −1 day −1 ) Calculated temperatures show good agreement in the summer hemisphere where planetary wave activity is negligible, but in the polar night of the winter hemisphere they are ∼30°K too cold which suggests planetary wave heating must make up the deficit. With observed ozone densities our globally averaged radiative equilibrium temperatures in the 65–75 km region are too cold and an additional heat source ∼1°K day −1 is required.
Finite-difference time-domain analysis of photonic nanojets from liquid-crystal-containing microcylinder (2013)

The photonic nanojet (PNJ) from a microcylinder with liquid crystals (LCs) showing tangential molecular alignment inside the microcylinder has been numerically analyzed on the basis of the finite-difference time-domain method. By introducing a small degree of birefringence, the characteristics of the PNJ, such as propagation length and polarization state, can be drastically changed. The azimuth angle and the ellipticity of the elliptically polarized PNJ obtained from the LC microcylinder changes within the propagation lengths in the micrometer range even in the isotropic matrix, which might be attributed to the jet like spatial profile of the PNJ. By using LC microcylinders or microspheres, we may obtain a rich variety of PNJs with unique polarization characteristics, which might open a new avenue for the development of novel optical devices with electrical tunability.
Consumption of High‐Oleic Peanuts Reduces LDL Cholesterol in Golden Syrian Hamsters (2010)

The Florida‐07 peanut contains more oleic acid vs. standard peanut strains. Consumption of oleic acid, a major constituent of olive oil, may favorably influence blood lipid levels. To determine if consumption of high‐oleic peanuts improved lipid metabolism standard rodent diets were modified to provide either high‐oleic acid utilizing the F‐07 peanut or the AP‐3 peanut containing lower levels of oleic acid. Two peanut‐free, high‐ and low‐oleic control diets were prepared using non‐peanut products (olive and corn oil). Male Golden Syrian Hamsters (n=8/group) were provided free access to diets for 33.5 days and diets were removed 36 h prior to termination of the study. ANOVA indicated a significant reduction in LDL‐cholesterol levels in hamsters consuming peanuts (1.34±0.38 vs. 1.68±0.26 mmol/L; P&lt;0.05); further, hamsters consuming high levels of oleic acid from peanuts had lower LDL‐cholesterol compared to hamsters consuming the same level of oleic acid in a non‐peanut diet (1.26±0.39 vs. 1.72±0.13 mmol/L; P&lt;0.05). Our data indicate beneficial effects of consumption of oleic acid and the possibility that a non‐oleic acid component of peanut may help reduce LDL levels.
Serological cross-reactions between Mycoplasma genitalium and Mycoplasma pneumoniae (1984)

The recently discovered mycoplasma species Mycoplasma genitalium was isolated from urethral specimens from men with nongonococcal urethritis (Tully et al., Lancet i:1288-1291, 1981). In a previous report (K. Lind, Lancet ii:1158-1159, 1982), prominent serological cross-reactions were demonstrated between this mycoplasma and M. pneumoniae. In the present study, the two mycoplasma species were compared more extensively. In classical mycoplasma medium without thallium acetate, M. genitalium grew more slowly than M. pneumoniae did but finally formed similar amounts of acetic acid and lactic acid from glucose. Although their colonies on solid medium were indistinguishable, transmission electron microscopy showed that the flask-formed cells of M. genitalium (especially their necks) were shorter than those of M. pneumoniae. The two species were distinct since DNA hybridization showed only 1.8% homology in base sequences, and sodium dodecyl sulfate-polyacrylamide gel electrophoresis revealed significantly different profiles of the two strains. However, considerable similarities were found in their antigenic reactions in various serological tests. The presence of common or closely related antigens was demonstrated in the two species with rabbit immune sera in complement fixation test with chloroform-methanol-extracted antigens by an indirect immunofluorescence test on microcolonies, and by metabolism inhibition and growth inhibition tests. Cross-reactions were also demonstrated by crossed immunoelectrophoresis. The role of M. genitalium as a human pathogen in the genital tract has not been assessed. If serological tests are to be used in this assessment, caution must be exercised due to the extensive cross-reactions demonstrated. Some of the species-specific antigens which we have demonstrated would be appropriate for use in such tests and would help to circumvent problems caused by cross-reactions.
Programmable Hash Functions from Lattices: Short Signatures and IBEs with Small Key Sizes. (2016)

Driven by the open problem raised by Hofheinz and Kiltz [34], we study the formalization of lattice-based programmable hash function PHF, and give two types of constructions by using several techniques such as a novel combination of cover-free sets and lattice trapdoors. Under the Inhomogeneous Small Integer Solution ISIS assumption, we show that any non-trivial lattice-based PHF is collision-resistant, which gives a direct application of this new primitive. We further demonstrate the power of lattice-based PHF by giving generic constructions of signature and identity-based encryption IBE in the standard model, which not only provide a way to unify several previous lattice-based schemes using the partitioning proof techniques, but also allow us to obtain a new short signature scheme and a new fully secure IBE scheme with keys consisting of a logarithmic number of matrices/vectors in the security parameter $$\kappa $$. Besides, we also give a refined way of combining two concrete PHFs to construct an improved short signature scheme with short verification keys from weaker assumptions. In particular, our methods depart from the confined guessing technique of Bohl et al. [8] that was used to construct previous standard model short signature schemes with short verification keys by Ducas and Micciancio [24] and by Alperin-Sheriff [6], and allow us to achieve existential unforgeability against chosen message attacks EUF-CMA without resorting to chameleon hash functions.
Obesity‐related Polymorphisms and Their Associations With the Ability to Regulate Fat Oxidation in Obese Europeans: The NUGENOB Study (2009)

Both obesity and insulin resistance have been related to low fat oxidation rates, which may be genetically determined. The association between variation in fat oxidation rates among obese subjects and genotype was studied for 42 common single-nucleotide polymorphisms (SNPs) in 26 candidate genes for fat oxidation, insulin resistance, and obesity, including FTO. Energy expenditure (EE) and fat oxidation were measured with indirect calorimetry during fasting and 3 h after a high fat load containing 95 energy% of fat (60% saturated fat, energy content 50% of estimated resting EE) in 722 obese subjects (541 women, 181 men) from 8 European centers. After adjustment for center and gender, -178 A>C CD36 (rs2232169) (P = 0.02), -22510 C>G SLC6A14 (women, rs2011162) (P = 0.03), and T690S C>G PCSK1 (rs6235) (P = 0.02) were related to a reduced fat oxidation, whereas 17 C>G SREBF1 (17 C>G) (P = 0.01) was related to increased fat oxidation in the fasting state. The ability to increase fat oxidation after a high fat load was increased in subjects with -174 G>C IL6 (rs1800795) (P = 0.01). Effect sizes range from 1.1 to 3.1% differences in fat oxidation (expressed as % of EE). FTO rs9939609 was not related to fat oxidation. At the same time, the results are not adjusted for multiple testing, thus none of the associations can be considered statistically significant. The results should therefore only be considered as leads to new hypotheses about effects of specific genetic polymorphisms on fasting and postprandial fat oxidation.
Autoantibody synthesis in the central nervous system of patients with paraneoplastic syndromes (1990)

We measured the activity of 2 highly specific autoantibodies (anti-Yo associated with paraneoplastic cerebellar degeneration and anti-Hu associated with paraneoplastic sensory neuronopathy-encephalomyelitis) in simultaneously procured samples of serum and CSF of 18 patients. We also measured the effect of plasma exchange on autoantibody activity in serum and CSF of 6 patients. In 11 patients with paraneoplastic cerebellar degeneration, the CSF/serum ratio of anti-Yo antibody varied between 0.74 and 63, with 8 of 11 patients having ratios substantially greater than 1. In 7 patients with paraneoplastic sensory neuronopathy-encephalomyelitis, the CSF/serum ratio of anti-Hu antibody varied from 0.6 to 44, with 6 of 7 patients having ratios greater than 1. Plasmapheresis reduced the level of the autoantibody in serum without affecting that in the CSF in 5 of 6 patients. These data indicate that autoantibodies in paraneoplastic syndromes are produced in the CNS. This is consistent with the hypothesis of autoimmunity as the pathogenic mechanism. Plasmapheresis failed to effectively remove the antibody from the CNS.
PARP-1 deregulation in multiple sclerosis (2019)

Given the importance of PARP-1 in inflammatory processes, its upregulation in multiple sclerosis lymphocyte populations suggests a potential role in the immune pathogenesis of multiple sclerosis. Strikingly higher PARP-1 expression in progressive multifocal leukoencephalopathy cases suggests its involvement in progressive multifocal leukoencephalopathy disease pathomechanisms. These results further support the value of PARP-1 inhibitors as a potential novel therapeutic strategy for multiple sclerosis and natalizumab-associated progressive multifocal leukoencephalopathy.
Editorial for January 2009 (2009)

ADVERTISEMENT RETURN TO ISSUEEditorialNEXTEditorial for January 2009George C. SchatzCite this: J. Phys. Chem. B 2009, 113, 1, 1Publication Date (Web):January 2, 2009Publication History Published online2 January 2009Published inissue 8 January 2009https://pubs.acs.org/doi/10.1021/jp810597khttps://doi.org/10.1021/jp810597keditorialACS PublicationsCopyright © 2009 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views672Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (42 KB) Get e-AlertscloseSUBJECTS:Physical chemistry Get e-Alerts
THE EFFECT OF DRYING TEMPERATURE ON THE MECHANO-SORPTIVE BEHAVIOR OF RED OAK LUMBER (1994)

ABSTRACT Matched units of 3.2 cm thick red oak lumber were dried simultaneously in a steam heated and dehumidification kiln. The two pairs of runs are designated Set I and Set II. The objective was to compare the mechano-sorptive behavior and board shrinkages while using the recommended U.S. Forest Products Laboratory schedule with the steam kiln and comparatively low temperature drying in the dehumidification kiln. Drying rates in Set I and Set II were comparable for the two kilns up to approximately 450 hours, which illustrated the dependence of the drying rate on the relative humidity of the kiln air rather than its temperature. Subsequently, the stepwise increases in dry bulb temperature for the steam kiln were accompanied by accelerated drying. Less compression set developed in the interior mechano-sorptive slices for the dehumidification kiln runs. On an average, the maximum compression set for the core slices from the dehumidification kiln was about S0% of that for core slices from the steam heated kiln. Simultaneously the surface slices from the dehumidification kiln developed more tension set than those from the steam heated kiln. Board width shrinkage at the end of drying, at the same average moisture content, was greatest for the steam kiln. The greater shrinkage is attributed to greater compression set due to the higher drying temperatures. These results support McMillen)s explanation for the effect of drying temperatures upon sets and the shrinkage of red oak lumber.
Data from Detection of Hepatocellular Carcinoma Using Glycomic Analysis (2023)

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; Hepatocellular carcinoma (HCC) represents an increasing health problem in the United States. Serum α-fetoprotein, the currently used clinical marker, is elevated in only ∼60% of HCC patients; therefore, the identification of additional markers is expected to have significant public health impact. The objective of our study was to quantitatively assess N-glycans originating from serum glycoproteins as alternative markers for the detection of HCC.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; We used matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for quantitative comparison of 83 N-glycans in serum samples of 202 participants (73 HCC cases, 77 age- and gender-matched cancer-free controls, and 52 patients with chronic liver disease). N-glycans were enzymatically released from serum glycoproteins and permethylated before mass spectrometric quantification.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt; The abundance of 57 N-glycans was significantly altered in HCC patients compared with controls. The sensitivity of six individual glycans evaluated for separation of HCC cases from population controls ranged from 73% to 90%, and the specificity ranged from 36% to 91%. A combination of three selected N-glycans was sufficient to classify HCC with 90% sensitivity and 89% specificity in an independent validation set of patients with chronic liver disease. The three N-glycans remained associated with HCC after adjustment for chronic viral infection and other known covariates, whereas the other glycans increased significantly at earlier stages of the progression of chronic viral infection to HCC.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusion:&lt;/b&gt; A set of three identified N-glycans is sufficient for the detection of HCC with 90% prediction accuracy in a population with high rates of hepatitis C viral infection. Further evaluation of a wider clinical utility of these candidate markers is warranted.&lt;/p&gt;&lt;/div&gt;
Faculty Opinions recommendation of Evidence that rice and other cereals are ancient aneuploids. (2003)

Detailed analyses of the genomes of several model organisms revealed that large-scale gene or even entire-genome duplications have played prominent roles in the evolutionary history of many eukaryotes. Recently, strong evidence has been presented that the genomic structure of the dicotyledonous model plant species Arabidopsis is the result of multiple rounds of entire-genome duplications. Here, we analyze the genome of the monocotyledonous model plant species rice, for which a draft of the genomic sequence was published recently. We show that a substantial fraction of all rice genes ( approximately 15%) are found in duplicated segments. Dating of these block duplications, their nonuniform distribution over the different rice chromosomes, and comparison with the duplication history of Arabidopsis suggest that rice is not an ancient polyploid, as suggested previously, but an ancient aneuploid that has experienced the duplication of one-or a large part of one-chromosome in its evolutionary past, approximately 70 million years ago. This date predates the divergence of most of the cereals, and relative dating by phylogenetic analysis shows that this duplication event is shared by most if not all of them. PMID: 12953120
Spread of Carbapenem-Resistant Acinetobacter baumannii Global Clone 2 in Asia and AbaR-Type Resistance Islands (2013)

In this surveillance study, we identified the genotypes, carbapenem resistance determinants, and structural variations of AbaR-type resistance islands among carbapenem-resistant Acinetobacter baumannii (CRAB) isolates from nine Asian locales. Clonal complex 92 (CC92), corresponding to global clone 2 (GC2), was the most prevalent in most Asian locales (83/108 isolates; 76.9%). CC108, or GC1, was a predominant clone in India. OXA-23 oxacillinase was detected in CRAB isolates from most Asian locales except Taiwan. blaOXA-24 was found in CRAB isolates from Taiwan. AbaR4-type resistance islands, which were divided into six subtypes, were identified in most CRAB isolates investigated. Five isolates from India, Malaysia, Singapore, and Hong Kong contained AbaR3-type resistance islands. Of these, three isolates harbored both AbaR3- and AbaR4-type resistance islands simultaneously. In this study, GC2 was revealed as a prevalent clone in most Asian locales, with the AbaR4-type resistance island predominant, with diverse variants. The significance of this study lies in identifying the spread of global clones of carbapenem-resistant A. baumannii in Asia.
ChemInform Abstract: REGIO‐ AND STEREOSELECTIVITY OF THE METAL‐INDUCED RING OPENING OF DI‐ AND TETRAMETHYLSPIRO(2.4)HEPTA‐4,6‐DIENES (1985)

Abstract Die Regio‐ und Stereoselektivität der metallinduzierten Ringöffnung der methylsubstituierten Spiro[2.4]hepta‐4,6‐diene (I)‐(III) mit Ni‐, Mo‐ und Fe‐carbonylen wird untersucht.
A novel distributed feedback laser diode structure for an optical wavelength tunable filter (1997)

We have studied the effects of introducing phaseshifts in the active section of a m phaseshift-controlled DFB wavelength tunable filter on tuning range, peak power transmissivity and side-mode suppression ratio (SMSR). The analysis indicates that when the filter wavelength tuning range is 22.1 Å for the grating coupling coefficient while maintaining almost constant transmissivity (gain) of more than 35 dB. The filter SMSR ranges from 11.1 to 25.4 dB. The results for asymmetric values of and are also given.
The effect of distributed exchange parameters on magnetocaloric refrigeration capacity in amorphous and nanocomposite materials (2012)

The temperature dependent magnetization of nanocomposite alloys has been fit with a modified Handrich-Kobe equation with an asymmetric exchange fluctuation parameter combined with the Arrott-Noakes equation. The two equations of state are combined to calculate the entropy change in the magnetocaloric effect associated with the ferromagnetic to paramagnetic phase transformation. The complete fit for the M(T) of (Fe70Ni30)88Zr7B4Cu nanocomposite powder is accomplished by combining the two theories. We investigate the broadening of the second-order transition arising from asymmetric exchange parameters and resulting from the fluctuations of interatomic spacing found in an amorphous matrix and the asymmetric dependence of exchange energy on interatomic spacing. The magnetic entropy curve revealed extra broadening with a refrigeration capacity (RC) value of 135 J/kg at 5 T, which is comparable to (Fe76Cr8-xMoxCu1B15) ribbons, which have a RC value of 180 J/kg for the same applied field. Broadening of the magnetic entropy can lead to larger RC values and a wider working temperature range, making nanocomposite alloys promising for magnetocaloric applications.
A Study on Enterprise and Government Information Security Enhancement with Information Security Management System (2011)

According to the development of IT technology, life itself is becoming the change to Knowledge-based systems or information-based systems. However, the development of IT technology, the cyber attack techniques are improving. And DDoS a crisis occurs frequently, such as cyber terrorism has become a major data leakage. In addition, the various paths of attack from malicious code entering information in the system to work for your company for loss and damage to information assets is increasing. In this environment, the need to preserve the organization and users of information assets to perform ongoing inspections risk management processes within the organization should be established. Processes and managerial, technical, and physical systems by establishing an information security management system should be based. Also, we should be introduced information security product for protecting internal assets from the threat of malicious code incoming to inside except system and process establishment. Therefore we proposed enterprise and government information security enhancement scheme through the introduction of information security management system and information security product in this paper.
Lektion 5: Doppelschneckenextruder (2017)

No AccessTechnologie der ExtrusionDec 2017Lektion 5: DoppelschneckenextruderHelmut Greif, Andreas Limper, Gordon FattmannHelmut Greif, Andreas Limper, Gordon Fattmannhttps://doi.org/10.3139/9783446436947.005SectionsAboutPDF ToolsAdd to FavoritesDownload CitationTrack CitationsCopy LTI LinkPDF key 'share (en)' returned an object instead of string.FacebookTwitterEmailLinkedIn previous chapternext chapter FiguresReferencesRelatedDetails 2017Pages: 51-62Print ISBN: 978-3-446-43693-0eISBN: 978-3-446-43694-7 Copyright & Permissions© 2017 Carl Hanser Verlag GmbH & Co. KGPDF downloadLoading ...