gebhart/patrepeval huggingface dataset:
Steric and Hydrophobic Control Over Sequence-Defined Peptide Templates to Modulate the Properties of Polydiacetylene Nanomaterials (2022)

Precision control over molecular structure-function correlations in adaptive conjugated polymers such as polydiacetylene (PDA) is rarely demonstrated in completely aqueous environments due to solvent incompatibility, yet critical for realizing their biomedical applications. For PDAs, the chromogenic transitions that are key to their stimuli-responsiveness depend on the conformation and electronic structure of the π-conjugated backbone, which can be influenced by the nature of flanking, solubilizing groups that guide the topochemical polymerization of PDAs. Here, we investigate the dependence of amphiphilic polydiacetylene properties based on the characteristic contributions of amino acids that comprise the peptide segments serving as a biomimetic template for diacetylene polymerization in water. While sequence engineering has long been used as an effective approach to tune the function of peptide- or protein-based materials, it remains elusive how the interplay between steric effects and hydrophobicity at the residue level can impact the assembly behavior and the bulk properties of the resulting materials from hierarchically ordered 1-D nanostructures. We leverage the strict geometric requirements needed to topochemically polymerize diacetylenes bearing hexameric peptide moieties to systematically probe the impact of molecular volume and polarity changes brought by dipeptide substitution domains to the assembly behavior, photophysics, electrical properties, and biocompatibility of peptide-PDA assemblies. From a series of peptide-diacetylene monomers with systematically varied sequence, we show that steric contributions predominate the resulting photophysical properties, but the trends in the formation of higher order assemblies comprising the film bioscaffolds are distinct from the trends in PDA electronic structure changes driven by the peptide templates due to the combined impact of sterics and hydrophobicity. This work demonstrates how sequence-tunable, biomimetic interactions can be used as a synthetic handle to rationally tune PDA properties across length scales.
8-channel hyperfine WDm demultiplexer using a virtually-imaged phased-array (VIPA) (2004)

We demonstrate an 8-channel hyperfine wavelength demultiplexer at 1.55 /spl mu/m using a virtually-imaged phased-array spectral disperser, with channel spacings /spl sim/ 3 GHz (24 pm) and minus;3 dB channel bandwidths of /spl sim/ 0.75 GHz (6 pm).
Synthesis and Polymerization of Methyl α-Fluroacrylate (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and Polymerization of Methyl α-FluroacrylateCharles U. Pittman, Mitsuru Ueda, Kiyoshi Iri, and Yoshio ImaiCite this: Macromolecules 1980, 13, 5, 1031–1036Publication Date (Print):September 1, 1980Publication History Published online1 May 2002Published inissue 1 September 1980https://pubs.acs.org/doi/10.1021/ma60077a002https://doi.org/10.1021/ma60077a002research-articleACS PublicationsRequest reuse permissionsArticle Views446Altmetric-Citations36LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Model predictions of ozone changes (1985)

The predictions of several one-dimensional models were examined for a number of prescribed scenarios in steady-state or time-dependent approximations. A small number of two-dimensional steady-state calculations for a limited number of scenarios were compared with the results of one-dimensional models. The sensitivity of the calculated predictions to the values of input parameters were examined in order to assess recognized uncertainties in these predictions.
A study of variance in measurements of tank-treading frequency in populations of normal human red cells. (1983)

The statistical variance in rheoscopic measurements of tank-treading frequency ( TTF ) of normal human red cells has been investigated and the sources of this variance analyzed. Experiments were designed to expose the influence of donor, the stability of a donor's cells over a 2-month period, storage time from venipuncture to testing, cell age, applied shear rate and variations in the rheoscope gap due to trial-to-trial manipulation. The results show that the TTF varies linearly with applied shear rate within the range 20 to 180 s-1 and is strongly dependent on cell age. The slope of the TTF characteristic is not significantly different in cells taken from different, but hematologically normal adults nor does it change significantly over time in a particular donor. TTF measurements may be useful in distinguishing rheologically abnormal cell populations which differ from normal cells by at least 10%.
Optimal Context Quantization in Lossless Compression of Image Data Sequences (2004)

In image compression context-based entropy coding is commonly used. A critical issue to the performance of context-based image coding is how to resolve the conflict of a desire for large templates to model high-order statistic dependency of the pixels and the problem of context dilution due to insufficient sample statistics of a given input image. We consider the problem of finding the optimal quantizer Q that quantizes the K-dimensional causal context Ct = (Xt-t1,Xt-t2,...,X t-tK) of a source symbol Xt into one of a set of conditioning states. The optimality of context quantization is defined to be the minimum static or minimum adaptive code length of given a data set. For a binary source alphabet an optimal context quantizer can be computed exactly by a fast dynamic programming algorithm. Faster approximation solutions are also proposed. In case of m-ary source alphabet a random variable can be decomposed into a sequence of binary decisions, each of which is coded using optimal context quantization designed for the corresponding binary random variable. This optimized coding scheme is applied to digital maps and alpha-plane sequences. The proposed optimal context quantization technique can also be used to establish a lower bound on the achievable code length, and hence is a useful tool to evaluate the performance of existing heuristic context quantizers.
A Defected Ground Structure (DGS) for Reducing the Mutual Coupling of Dual Polarized Microstrip Antennas (2018)

Here, we present a novel defected ground structure (DGS) to reduce the mutual coupling between the dual polarized microstrip antenna elements. The DGS is composed by the line slot and the parasitic stub on the line slot, both of which are arranged vertically to the current respectively. The proposed DGS is small in size and simple in structure. DGS disturbs the electromagnetic field distribution between the antennas, and has the function of spatial filtering. The simulation results indicate that -19dB and -24dB mutual coupling reduction between dual polarized microstrip antenna elements are achieved.
Stichwortverzeichnis (2021)

You have accessMasing Handbuch QualitätsmanagementAug 2021StichwortverzeichnisTilo Pfeifer, Robert SchmittTilo Pfeifer, Robert Schmitthttps://doi.org/10.3139/9783446466210.bmSectionsAboutPDF ToolsAdd to FavoritesDownload CitationTrack CitationsCopy LTI LinkPDF ShareFacebookTwitterEmailLinkedIn previous chapter FiguresReferencesRelatedDetails 2020Pages: 1079-1091Print ISBN: 978-3-446-46230-4eISBN: 978-3-446-46621-0 Copyright & Permissions© 2021 Carl Hanser Verlag GmbH & Co. KGPDF DownloadLoading ...
Coupling model interpretation of dielectric relaxation of poly(vinyl acetate) near T g (1987)

Recent dielectric relaxation measurements on poly(vinyl acetate), PVAc, by Nozaki and Mashimo (NM) have demonstrated temperature and frequency dependences for well-annealed samples near the glass transition temperature Tg which cannot be explained by conventional theories or concepts. NM concluded that a new concept has to be introduced to interpret the dielectric behavior of PVAc near Tg. We demonstrate that the coupling model of relaxation is able to provide this new concept and can quantitatively describe the dielectric behavior at all temperatures. NM have carried out dielectric relaxation measurements between T=84.77 and 26.85 °C on a PVAc sample with Tg=31 °C. The samples were carefully annealed at each temperature to ensure that it is in equilibrium. NM found that the asymmetric dielectric loss curves become broader as temperature is lowered toward Tg with the most significant changes occurring near Tg. Furthermore the frequency of maximum loss fm was found to be described by the WLF equation (expected to be valid on the basis of free volume models) only at high temperatures. Extrapolation of the WLF curve to the glass transition region deviates significantly from the measurements. All of these phenomena are expected by the coupling model. The model predicts a relation between the shape of the dielectric loss curves and properties of the relaxation time. We demonstrate that the temperature dependence of fm is quantitatively predicted at all temperatures, including the deviations from WLF behavior near Tg. The same coupling model was previously shown to resolve several other problems in polymer physics near Tg.
Design and Comparison of High-Reliable Radiation-Hardened Flip-Flops Under SMIC 40nm Process (2016)

With the need for fast and low-power radiation-hardened processors, advanced technology process is applied to obtain both high performance as well as high reliability. However, scaling down of the size of the transistor makes the transistor sensitive to outside disturbances, such as soft error introduced by the strikes of the cosmic neutron beams. Besides aerospace applications, such reliability should also be taken into consideration for the sub-100[Formula: see text]nm CMOS designs to ensure the robustness of the circuit. In such circumstances, several radiation-hardened flip-flops are designed and simulated under SMIC 40[Formula: see text]nm process. Simulation results show that with five aspects (performance, power, area, PVT variation and reliability) taken into consideration, TSPC-based DICE and TMR combined architecture has the best soft-error robustness in comparison with other radiation-hardened flip-flops, and the critical charge of such architecture is 490[Formula: see text]fC, which is 12.5X higher than the traditional unhardened flip-flop.
Aging, microglial cell priming, and the discordant central inflammatory response to signals from the peripheral immune system (2008)

Recent studies suggest that activation of the peripheral immune system elicits a discordant central (i.e., in the brain) inflammatory response in aged but otherwise healthy subjects compared with younger cohorts. A fundamental difference in the reactive state of microglial cells in the aged brain has been suggested as the basis for this discordant inflammatory response. Thus, the aging process appears to serve as a "priming" stimulus for microglia, and upon secondary stimulation with a triggering stimulus (i.e., peripheral signals communicating infection), these primed microglia release excessive quantities of proinflammatory cytokines. Subsequently, this exaggerated cytokine release elicits exaggerated behavioral changes including anorexia, hypersomnia, lethargy, decreased social interaction, and deficits in cognitive and motor function (collectively known as the sickness behavior syndrome). Whereas this reorganization of host priorities is normally adaptive in young subjects, there is a propensity for this response to be maladaptive in aged subjects, resulting in greater severity and duration of the sickness behavior syndrome. Consequently, acute bouts of cognitive impairment in elderly subjects increase the likelihood of poor self-care behaviors (i.e., anorexia, weight loss, noncompliance), which ultimately leads to higher rates of hospitalization and mortality.
Consistency maintenance in real-time collaborative graphics editing systems (2002)

Real-time collaborative graphics editing systems allow a group of users to view and edit the same graphics document at the same time from geographically dispersed sites connected by communication networks. Consistency maintenance in the face of concurrent accesses to shared objects is one of the core issues in the design of these types of systems. In this article, we propose an object-level multiversioning approach to consistency maintenance in real-time collaborative graphic editors. This approach is novel in achieving intention preservation and convergence, in preserving the work concurrently produced by multiple users in the face of conflict, and in minimizing the number of object versions for conflict resolution. Major technical contributions of this work include a formal specification of a unique combined effect for an arbitrary group of conflict and compatible operations, a distributed algorithm for incremental creation of multiple object versions, a consistent object identification scheme for multiple object versions, and a convergent layering scheme for overlapping objects. All algorithms and schemes presented in this article have been implemented in an Internet-based GRACE (graphics collaborative editing) system.
Pulse-Width Modulation Neuron Implemented by Single Positive-Feedback Device (2021)

Positive-feedback (PF) device and its operation scheme to implement pulse width modulation (PWM) function was proposed and demonstrated, and the device operation mechanism for implementing PWM function was analyzed. By adjusting the amount of the charge stored in the n- floating body (Qn), the potential of the floating body linearly changes with time. When Qn reaches to a threshold value (Qth), the PF device turns on abruptly. From the linear time-varying property of Qn and the gate bias dependency of Qth, fully functionable PWM neuron properties including voltage to pulse width conversion and hard-sigmoid activation function were successfully obtained from a single PF device. A PWM neuron can be implemented by using a single PF device, thus it is beneficial to extremely reduce the area of a PWM neuron circuit than the previously reported one.
Prediction of Pocket-Portable and Implantable Glucose Enzyme Electrode Performance from Combined Species Permeability and Digital Simulation Analysis (1994)

Development of enzyme electrode sensors can be facilitated by the use of computer simulation modeling techniques. In this work, the model accounts for contacting solution effects, changes in species diffusion and partition coefficients across multiple membrane layer interfaces, cofactor limitation effects, enzyme loading, enzyme kinetics and decay, and other variations in electrode layer geometry. Experimentally determined single species membrane permeabilities are included in the digital simulations to predict the performance characteristics of a multilayered glucose oxidase based enzyme electrode. Information obtained includes range of sensor linearity under different substrate and cofactor concentration combinations, sensor time response and output as permeability parameters and enzyme loading are varied, sensor washout and interference effects, and prediction of decay of sensor enzyme concentration and resultant estimated sensor lifetime as a function of contacting solution conditions and sensor permeability.
Hepatopulmonary syndrome: Use of extracorporeal life support for life-threatening hypoxia following liver transplantation (2008)

Hepatopulmonary syndrome is an uncommon complication of nonacute liver failure, and in rare cases, hypoxia may be the presenting sign of liver dysfunction. The condition, once thought to be a contraindication, is improved in most cases by transplantation. There is a significant risk of postoperative, hypoxia-related morbidity and mortality in patients with hepatopulmonary syndrome. We present a case of life-threatening hypoxia following liver transplantation for liver failure and associated hepatopulmonary syndrome, with successful management using extracorporeal membrane oxygenation.
Capsaicin‐induced cardioprotection is driven by its hypothermic effect (1154.1) (2014)

Objective. We hypothesized that cardioprotective properties of topical capsaicin (CAP) application are related to its hypothermic effect. Methods. Anesthetized rats received CAP cream or vehicle (VCL) applied 15‐30 minutes before a 30‐minute coronary artery occlusion followed by 2‐hour reperfusion. At the end of the protocol, hearts were excised and the area at risk (AR), area of necrosis (AN) and infarct size (AN/AR) were measured. In additional set of animals, hearts were excised at the end of CAP/VCL application, and used for Western Blot assay of p‐Akt and p‐Erk1/2. Results. CAP cream produced a rapid decrease in pre‐occlusion core temperature, ranging from 0.22 to 1.78°C, with a median reduction of 0.97°C. In a CAP subgroup with a temperature decrease of &gt; 0.97°C, AN/AR was decreased by 31% (from 56±4% in the VCL group to 38±4% in the CAP group, p&lt;0.05). In the CAP subgroup with temperature decrease &lt; 0.97°C no difference in the infarct size was observed. CAP induced an increase in p‐Akt and p‐Erk1/2. Phosphorylation of downstream p70S6 was unaffected. Levels of p‐Akt‐ and p‐Erk1/2 did not correlate with temperature at pre‐occlusion. Conclusion. In the current study we for the first time demonstrated that cardioprotective effect of capsaicin might be related to mild hypothermia, caused by its topical application. Salvage kinase pathway appears not to be critical for the cardioprotective effects of capsaicin.
Fresh meat color (1973)

This review presents a critical evaluation of the recent developments in the study of fresh meat color. Importance of color as a primary quality attribute deciding the consumer acceptance of fresh meats, is pointed out. The stability of myoglobin pigment, essential for the maintenance of fresh meat color, is examined in the light of 3‐dimensional structure of the molecule. The dynamic and reversible nature of color cycle involving constant oxygenation, oxidation, and reduction is emphasized. Oxygenation and oxidation are discussed on the basis of thermodynamic principles. The factors affecting fresh meat color are examined. The enzymic and nonenzymic metmyoglobin reducing systems are discussed in relation to fresh meat color. A full discussion on the inter‐relationship between lipid and pigment oxidation is presented. Recent developments on the methodology of color measurement are traced, pointing out the advantages and limitations of various methods.
Ca18.75Li10.5[Al39N55]:Eu2+—Supertetrahedron Phosphor for Solid-State Lighting (2016)

Highly efficient red-emitting luminescent materials deliver the foundation for next-generation illumination-grade white light-emitting diodes (LEDs). Recent studies demonstrate that the hardly explored class of nitridoaluminates comprises intriguing phosphor materials, e.g., Sr[LiAl3N4]:Eu2+ or Ca[LiAl3N4]:Eu2+. Here, we describe the novel material Ca18.75Li10.5[Al39N55]:Eu2+ with highly efficient narrow-band red emission (λem ≈ 647 nm, full width at half-maximum, fwhm ≈ 1280 cm–1). This compound features a rather uncommon crystal structure, comprising sphalerite-like T5 supertetrahedra that are composed of tetrahedral AlN4 units that are interconnected by additional AlN4 moieties. The network charge is compensated by Ca2+ and Li+ ions located between the supertetrahedra. The crystal structure was solved and refined from single-crystal and powder X-ray diffraction data in the cubic space group Fd3̅m (No. 227) with a = 22.415(3) Å and Z = 8. To verify the presence of Li, transmission electron microscopy (TEM) investigations including electron energy-loss spectroscopy (EELS) were performed. Based on the intriguing luminescence properties, we proclaim high potential for application in high-power phosphor-converted white LEDs.
DER EINFLUSS DES ALTERS AUF DIE SICHERHEIT VON KRAFTFAHRZEUGREIFEN (1985)

AUFGRUND PHYSIKALISCHER UND CHEMISCHER PROZESSE UNTERLIEGEN KRAFTFAHRZEUGREIFEN EINER ALTERUNG, WODURCH DIE FUNKTIONSTUECHTIGKEIT BEEINTRAECHTIGT WERDEN KANN. REIFEN, DIE AELTER ALS 10 JAHRE SIND, SOLLTEN NUR DANN VERWENDET WERDEN, WENN SIE VORHER STAENDIG UNTER NORMALEN BEDINGUNGEN IM EINSATZ WAREN. REIFEN AN WOHNWAGEN ALTERN BESONDERS SCHNELL, SO DASS DIESE SCHON NACH SECHS, SPAETESTENS ACHT JAHREN AUSGETAUSCHT WERDEN SOLLTEN. ZU BERUECKSICHTIGEN IST FERNER, DASS DIE SOGENANNTEN NEUREIFEN OFTMALS EIN JAHR ODER MEHRERE JAHRE ALT SIND, BIS SIE ZUM VERKAUF ANGEBOTEN WERDEN. BERICHTET WIRD UEBER DEN REIFENAUFBAU, DIE REIFENBEANSPRUCHUNG, DIE BEEINFLUSSUNG DER WERKSTOFFEIGENSCHAFTEN DURCH DIE ZEIT SOWIE DURCH MECHANISCHE UND THERMISCHE BEANSPRUCHUNGEN, SCHUTZMITTEL WERDEN DEN REIFEN BEIGEGEBEN, UM DIE ABHAENGIGKEIT DER WERKSTOFFEIGENSCHAFTEN DURCH ZEITEINFLUESSE SOWIE THERMISCHE UND MECHANISCHE BEANSPRUCHUNGEN SO GERING WIE MOEGLICH ZU HALTEN. UEBERALTERTE REIFEN KOENNEN GEWEBEBRUECHE UND GUERTELSEPARATIONEN AUFWEISEN.
Work hardening of dispersion-hardened crystals (1966)

Abstract A new theory of work hardening in dispersion-hardened single crystals—by which we mean soft crystals containing hard non-deforming particles of a second phase—is described. It is based on the fact that, if the particles do not deform plastically, and the interface between particle and matrix does not fracture, then secondary slip must occur locally round each particle when the crystal is deformed, even though the crystal may appear to deform by ‘single slip’. The density of secondary dislocations rises steeply with strain, and acts as a forest impeding the movement of primary glide dislocations. The theory predicts a relation between stress and strain (eqn. (9)) which is in good agreement with experimental results. Fracture of the particle-matrix interface, and the importance of the strength of this interface, are discussed.