gebhart/patrepeval huggingface dataset:
The development of solar-assisted gas-fired appliances: phase ii. Final report dec 80-nov 81 (1981)

An evaluation of applying solar assistance to commercial laundry drying and supermarket dehumidification was accomplished. The laundry drying project included experimental evaluation of the transient and steady-state characteristics of the hot air produced by an air-heating solar collector; experimental evaluation of the performance characteristics of a gas-fired laundry dryer as affected by varying the inlet air temperature and humidity; and an assessment of the characteristics of commercial laundries in relation to the potential commercialization of the solar-assisted dryer concept. The supermarket dehumidification project included an assessment of the relative latent and sensible cooling requirements as a function of geographic location; typical design studies of the performance and cost effectiveness of desiccant dehumidification systems in this application; and the incremental effectiveness of solar assistance to desiccant regeneration. In both projects, the solar-assist feature is, at best, marginally cost effective, including incentives, in the near term; however, the gas-fired only desiccant dehumidification concept is shown to be a potentially attractive alternative to vapor compression dehumidification with a potential for widespread application.
[Detection and analysis of SARS coronavirus-specific antibodies in sera from non-SARS children]. (2003)

No SARS coronavirus-specific antibody are present in the sera of non-SARS children.
Cofilin, a protein in porcine brain that binds to actin filaments and inhibits their interactions with myosin and tropomyosin (1984)

Cofilin, a 21 000 molecular weight protein of porcine brain, reacts stoichiometrically with actin in a 1:1 molar ratio. Upon binding of cofilin, the fluorescence of pyrene-labeled actin under polymerizing conditions is changed into the monomer form, irrespective of whether cofilin is added to actin before or after polymerization. Cofilin decreases the viscosity of actin filaments but increases the light-scattering intensity of the filaments. The centrifugation assay and the DNase I inhibition assay demonstrate that cofilin binds to actin filaments in a 1:1 molar ratio of cofilin to actin monomer in the filament and that cofilin increases the monomeric actin to a limited extent (up to 1.1-1.5 microM monomer) in the presence of physiological concentrations of Mg2+ and KCl. Cofilin is also able to bind to monomeric actin, as demonstrated by gel filtration. Electron microscopy showed that actin filaments are shortened and slightly thickened in the presence of cofilin. No bundle formation was observed in the presence of various concentrations of cofilin. The gel point assay using an actin cross-linking protein and the nucleation assay also suggested that cofilin shortens the actin filaments and hence increases the filament number. Cofilin blocks the binding of tropomyosin to actin filaments. Tropomyosin is dissociated from actin filaments by the binding of cofilin to actin filaments. Cofilin was found to inhibit the superprecipitation of actin-myosin mixtures as well as the actin-activated myosin ATPase. All these results suggest that cofilin is a new type of actin-associated protein.
Evidence of Systemic Dissemination ofChlamydia pneumoniaevia Macrophages in the Mouse (1998)

Chlamydia pneumoniae has been postulated to cause systemic disease by infection of monocytes/macrophages and spread via the blood or lymphatics. To investigate how C. pneumoniae disseminates, the ability of the organism to infect murine macrophages in vivo and whether infection can be transferred via macrophages were determined. C. pneumoniae was detected by direct plating, isolation, and polymerase chain reaction in alveolar macrophages from intranasally inoculated mice and peritoneal macrophages from intraperitoneally inoculated mice. C. pneumoniae were also detected in peripheral blood mononuclear cells, but not plasma, of intranasally and intraperitoneally inoculated mice. When alveolar or peritoneal macrophages were adoptively transferred by intraperitoneal injection from infected to uninfected mice, C. pneumoniae DNA was detected by polymerase chain reaction in lung, thymus, spleen, and/or abdominal lymph nodes. These results demonstrate the ability of C. pneumoniae to infect macrophages in vivo and to disseminate systemically via infected macrophages by hematogenous and lymphatic routes.
High energy product of MnBi by field annealing and Sn alloying (2019)

Permanent-magnet materials are one cornerstone of today’s technology, abundant in disk drives, motors, medical equipment, wind generators, and cars. A continuing challenge has been to reconcile high permanent-magnet performance with low raw-material costs. This work reports a Mn-Bi-Sn alloy exclusively made from inexpensive elements, exhibiting high values of Curie-temperature, magnetization, anisotropy, coercivity, and energy product. The samples are produced by field annealing of rapidly quenched Sn-containing MnBi alloys, where the improvement of the magnetic properties is caused by the substitutional occupancy of the 2c sites in the hexagonal NiAs structure by Sn. The substitution modifies the electronic structure of the compound and enhances the magnetocrystalline anisotropy, thereby improving the coercivity of the compound. The energy product reaches 114 kJ/m3 (14.3 MGOe) at room temperature and 86 kJ/m3 (10.8 MGOe) at 200 °C; this value is similar to that of the Dy-free Nd2Fe14B and exceeds that of other rare-earth-free permanent-magnet bulk alloys, as encountered in automotive applications.
Transcranial Magnetic Stimulation Predicts Functional Recovery after Botulinum Toxin Treatment in Stroke Patients (2013)

Spasticity is a disabling stroke complication. Despite the ascertained efficacy of botulinum toxin A (BoNT-A) in reducing spasticity, only few patients improve in upper limb active function and it is not possible on clinical basis to predict the response to treatment (1). Motor-evoked potential (MEP) recording after transcranial magnetic stimulation (TMS) of motor cortex may provide noninvasive evaluation of central motor pathways (2). We performed a prospective study in 14 chronic stroke patients with upper limb spasticity to assess the efficacy of TMS to predict upper limb functional response to one-time injections of BoNT-A. MEP findings were correlated with the change in the Action Research Arm Test (ARAT) score at one-month. Twelve patients (85·7%) had a reduction of spasticity and five of these patients (35·7%) also improved in the ARAT score. The presence of MEP in the affected hand had a positive predictive power of 57·1% and a negative predictive power of 85·7% of a functional improvement; thus, it is very unlikely that patients who have no MEP in affected hand respond to BoNT-A. These results confirm that BoNT-A reduces spasticity in stroke patients, and in some of them can also improve upper limb function. TMS may be useful in selecting the patients that are more likely to improve in upper limb function because it is more specific than clinic evaluation in assessing corticospinal pathway responsible for fine manipulatory finger movements (3). Fioravante Capone, Paolo Profice, Fabio Pilato, Anna Rita Bentivoglio, Tamara Ialongo, Raffaella Di Giacopo, Federico Ranieri, and Vincenzo Di Lazzaro* Institute of Neurology, Campus BioMedico University, Rome, Italy Fondazione Alberto Sordi – Research Institute for Ageing, Rome, Italy Department of Neurosciences, Universita Cattolica, Rome, Italy CeRiN (Center for Neurocognitive Rehabilitation), CIMeC (Center for Mind/Brain Sciences), University of Trento, Rome, Italy
Spatiospectral and picosecond spatiotemporal properties of a broad area operating channeled-substrate-planar laser array (1991)

Spatiospectral and spatiotemporal properties of an eight-element channeled-substrate-planar laser array are investigated in both cw and pulsed operating conditions. The closely spaced CSP array with strong optical coupling between array elements is characterized by a broad area laserlike operation determined by its spatial mode spectra. The spatiotemporal evolution of the near and far field exhibits complex dynamic behavior in the picosecond to nanosecond domain. Operating parameters for the laser device have been experimentally determined. These results provide important information for the evaluation of the dynamic behavior of coherent semiconductor laser arrays.
Localization of White Spotting Locus in Boxer Dogs on CFA20 by Genome-Wide Linkage Analysis with 1500 SNPs (2007)

New techniques allow fast genotyping of large numbers of single-nucleotide polymorphisms (SNPs) of the genome. These techniques are used to map disorders with complex inheritance patterns and require large study groups. Linkage analysis of monogenetic traits exploits close family relationships between relatively small numbers of cases and controls. Linkage studies are typically performed with a set of microsatellite markers spaced at 10 cM. We were interested to test whether SNP typing could be applied in genome-wide linkage analysis because of the speed of the procedure. White spotting in Boxer dogs was chosen as a model because it is a semidominant trait, allowing the assignment of locus genotypes to each phenotyped dog. A set of just more than 1500 SNPs were typed in 5 families with heterozygous parents and offspring that included 11 white, 6 brown, and 19 spotted dogs. Multipoint linkage analysis was performed and a LOD score of 12.1 was obtained on canine chromosome 20. The CFA20 region was the only region with a positive LOD score. The gene MITF, coding for a transcription factor implicated in Waardenburg syndrome in humans, is located in the region close to a SNP that is in apparent linkage disequilibrium with the white spotting locus. Thus, MITF is a likely candidate for involvement in white spotting in boxers. We conclude that SNPs, spaced at an average distance of 1.6 Mb, are highly informative in linkage analysis of monogenic traits and are a powerful alternative to microsatellite markers.
Sequence and Expression of Thai Rosewood -Glucosidase/ -Fucosidase, a Family 1 Glycosyl Hydrolase Glycoprotein (2000)

Dalcochinin-8'-O-beta-glucoside beta-glucosidase (dalcochinase) from the Thai rosewood (Dalbergia cochinchinensis Pierre) has aglycone specificity for isoflavonoids and can hydrolyze both beta-glucosides and beta-fucosides. To determine its structure and evolutionary lineage, the sequence of the enzyme was determined by peptide sequencing followed by PCR cloning. The cDNA included a reading frame coding for 547 amino acids including a 23 amino acid propeptide and a 524 amino acid mature protein. The sequences determined at peptide level were found in the cDNA sequence, indicating the sequence obtained was indeed the dalcochinase enzyme. The mature enzyme is 60% identical to the cyanogenic beta-glucosidase from white clover glycosyl hydrolase family 1, for which an X-ray crystal structure has been solved. Based on this homology, residues which may contribute to the different substrate specificities of the two enzymes were identified. Eight putative glycosylation sites were identified, and one was confirmed to be glycosylated by Edman degradation and mass spectrometry. The protein was expressed as a prepro-alpha-mating factor fusion in Pichia pastoris, and the activity of the secreted enzyme was characterized. The recombinant enzyme and the enzyme purified from seeds showed the same K(m) for pNP-glucoside and pNP-fucoside, had the same ratio of V(max) for these substrates, and similarly hydrolyzed the natural substrate, dalcochinin-8'-beta-glucoside.
Sustainable jute fiber reinforced polylactic acid composite: Thermochemical and thermomechanical characteristics (2023)

The necessity of utilizing biodegradable and naturally sourced materials is rising all over the world. The preferred composite today are mostly sustainable but compatibility issues between the matrix and fiber still requires further investigation. The study presents development of Jute fiber (JF) reinforced Polylactic acid (PLA) composite with Fusabond (FB) as an interfacial modifier by using extrusion. The addition of interfacial modifier enhanced the thermomechanical and thermochemical properties of resultant composite. The improvement in elastic modulus and tensile strength is evident when 30%JF with 3%FB was utilized. The DMA result shows that the addition of Fusabond as interfacial modifier in jute fiber reinforced polylactic acid composite improves the storage modulus and enhances the toughness by reducing tanδ peak. Furthermore, SEM micrograph demonstrates the improvement in interfacial suitability between jute fiber and polylactic acid matrix when Fusabond is added. The X-ray tomography result shows when jute fiber content is 30% in PLA matrix higher degree of anisotropy is achieved which is 29%.
High-performance strain-compensated InGaAs-GaAsP-GaAs (/spl lambda/=1.17 μm) quantum well diode lasers (2001)

This letter reports studies on highly strained and strain-compensated InGaAs quantum-well (QW) active diode lasers on GaAs substrates, fabricated by low-temperature (550/spl deg/C) metal-organic chemical vapor deposition (MOCVD) growth. Strain compensation of the (compressively strained) InGaAs QW is investigated by using either InGaP (tensile-strained) cladding layer or GaAsP (tensile-strained) barrier layers. High-performance /spl lambda/=1.165 μm laser emission is achieved from InGaAs-GaAsP strain-compensated QW laser structures, with threshold current densities of 65 A/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> for 1500-μm-cavity devices and transparency current densities of 50 A/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . The use of GaAsP-barrier layers are also shown to significantly improve the internal quantum efficiency of the highly strained InGaAs-active laser structure. As a result, external differential quantum efficiencies of 56% are achieved for 500-μm-cavity length diode lasers.
Further characterization of pigment‐producing Malassezia strains (2004)

Reference as well as field strains of Malassezia furfur (30), M. sympodialis (49), M. globosa (52), M. obtusa (one), M. restricta (one), M. slooffiae (seven), and M. pachydermatis (373) were investigated for their ability to produce pigment and fluorochromes when tryptophan (Trp) is offered as the main nitrogen source. Only the M. furfur strains produced pigment on a pigment-inducing medium (p-medium). Remarkably, the optical activity of Trp was not significant for pigment synthesis. Other nitrogen sources that are structurally similar to Trp (gramine, tryptamine, serotonin) did not induce pigment formation. All lipophilic non-furfur species failed to grow and to form pigment on this agar. However, growth of all lipid-dependent species was achieved on a modified Dixon agar in which peptone had been substituted by an equal amount of l-Trp. Here, too, the M. furfur colonies were characterized by rapidly developing dark brown halos. Furthermore, about 11% of the M. pachydermatis strains tested produced pigment formation on the p-medium, which was enhanced by addition of d-glucose. In contrast to M. furfur, pigment formation occurred after a markedly longer incubation time (4 weeks unlike 3-5 days) with a lower yield and limited color spectrum (thin layer chromatography, TLC). The UV filter pityriacitrine recently described for M. furfur was also demonstrated for M. pachydermatis by extraction, high-performance liquid chromatography (HPLC) analysis with co-elution and mass spectroscopy. The phenotypic feature of pigment formation in some strains of M. pachydermatis may confirm recent molecular-genetic findings suggesting a relationship between some strains of M. pachydermatis and M. furfur.
Range Extension Autonomous Driving for Electric Vehicle Based on Optimization of Velocity Profile in Consideration of Direct Yaw Moment (2016)

Intelligent Transport System (ITS) has been intensively studied in the last decade to solve environmental and energy problem by improving traffic flow. Along with the development of ITS and autonomous driving technologies, vehicle velocity will be decided by ITS. In this paper, range extension autonomous driving (READ) system which minimizes consumption energy for electric vehicle (EV) is proposed. The proposed method optimizes velocity profile and direct yaw moment simultaneously in consideration of cornering. The effectiveness of the proposed method is verified by simulations and experiments.
Surface Properties of Elastomeric Polypropylenes Studied with Atomic Force Microscopy (2008)

The energy dissipated between tip and sample during dynamic atomic force microscopy (AFM) is a sensitive measure of local surface properties. We mapped the surface properties of crystalline and amorphous regions in thin films of different kinds of elastomeric polypropylene (ePP) with 10 nm lateral resolution. The dissipated energy as a function of the amplitude setpoint displays discriminative shapes for both polymer regions. Differences in the shape as well as in the maximum amount of dissipated energy are interpreted as different amounts of amorphous material on top of crystalline regions. Indentation experiments at different amplitude setpoints resulted in indentation depths of the AFM tip up to 11 nm, on both crystalline and amorphous regions. This and the change of dissipated energy upon wet chemical etching indicate that crystalline regions are covered by an up to 10 nm thick amorphous layer.
Chondrogenesis of Infrapatellar Fat Pad Derived Adipose Stem Cells in 3D Printed Chitosan Scaffold (2014)

Infrapatellar fat pad adipose stem cells (IPFP-ASCs) have been shown to harbor chondrogenic potential. When combined with 3D polymeric structures, the stem cells provide a source of stem cells to engineer 3D tissues for cartilage repair. In this study, we have shown human IPFP-ASCs seeded onto 3D printed chitosan scaffolds can undergo chondrogenesis using TGFβ3 and BMP6. By week 4, a pearlescent, cartilage-like matrix had formed that penetrated the top layers of the chitosan scaffold forming a 'cap' on the scaffold. Chondrocytic morphology showed typical cells encased in extracellular matrix which stained positively with toluidine blue. Immunohistochemistry demonstrated positive staining for collagen type II and cartilage proteoglycans, as well as collagen type I. Real time PCR analysis showed up-regulation of collagen type II, aggrecan and SOX9 genes when IPFP-ASCs were stimulated by TGFβ3 and BMP6. Thus, IPFP-ASCs can successfully undergo chondrogenesis using TGFβ3 and BMP6 and the cartilage-like tissue that forms on the surface of 3D-printed chitosan scaffold may prove useful as an osteochondral graft.
Oil-water-rock wettability measurement (1981)

The recovery of oil depends on the wettability of the system, with more oil recovered from water-wet than from intermediate or oil-wet systems. Oil trapped in water-wet systems is in the form of small isolated pockets, while oil in oil-wet systems generally can be traced throughout the system. A quantitative method for the determination of wettability has been developed, based on the thermodynamic properties of capilliary systems. The test can be used to determine the physical and chemical relationships existing in oil-water-rock systems. A small amount of the polar extract from any crude oil will produce a large change in the wettability of a saturated mineral oil-water-rock system, making it more oil wetting. This changes the water-oil distributions within the pores by displacement of water from the small pores by oil and displacement of the adsorbed (hydrogen bonded) monolayer of water from the rock surface. The result is a decrease in production by waterflood.
Paecilomyces variotii xylanase production, purification and characterization with antioxidant xylo-oligosaccharides production (2021)

Paecilomyces variotii xylanase was, produced in stirred tank bioreactor with yield of 760 U/mL and purified using 70% ammonium sulfate precipitation and ultra-filtration causing 3.29-fold purification with 34.47% activity recovery. The enzyme purity was analyzed on sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) confirming its monomeric nature as single band at 32 KDa. Zymography showed xylan hydrolysis activity at the same band. The purified enzyme had optimum activity at 60 °C and pH 5.0. The pH stability range was 5-9 and the temperature stability was up 70 °C. Fe<sup>2+</sup>and Fe<sup>3+</sup> exhibited inhibition of xylanase enzyme while Cu<sup>2+</sup>, Ca<sup>2+</sup>, Mg<sup>2+</sup> and Mn<sup>2+</sup> stimulated its activity. Mercaptoethanol stimulated its activity; however, Na<sub>2</sub>-EDTA and SDS inhibited its activity. The purified xylanase could hydrolyze beechwood xylan but not carboxymethyl cellulose (CMC), avicel or soluble starch. Paecilomyces variotii xylanase K<sub>m</sub> and V<sub>max</sub> for beechwood were determined to be 3.33 mg/mL and 5555 U/mg, respectively. The produced xylanase enzyme applied on beech xylan resulted in different types of XOS. The antioxidant activity of xylo-oligosaccharides increased from 15.22 to 70.57% when the extract concentration was increased from 0.1 to 1.5 mg/mL. The enzyme characteristics and kinetic parameters indicated its high efficiency in the hydrolysis of xylan and its potential effectiveness in lignocellulosic hydrolysis and other industrial application. It also suggests the potential of xylanase enzyme for production of XOS from biomass which are useful in food and pharmaceutical industries.
NMR Imaging of High-Amylose Starch Tablets. 2. Effect of Tablet Size (2002)

Carbohydrate polymers are widely used for pharmaceutical applications such as the controlled release of drugs. The swelling and water mobility in high-amylose starch tablets are important parameters to be determined for these applications. They have been studied at different time intervals by nuclear magnetic resonance imaging (NMRI) after the immersion of the samples in water. These tablets have a hydrophilic matrix, which swells anisotropically and forms a hydrogel in water. NMRI shows clearly the anisotropy of the water penetration and the swelling along the radial and axial dimensions of the tablets. Empirical relationships are established to describe the kinetics of water penetration and swelling of the tablets. Results show that water uptake and tablet swelling strongly depend on the size of the tablets. Gravimetric measurements of water uptake were also performed in comparison with the NMRI results.
The Development of an Ecologically Valid Test for Assessing Patients with a Dysexecutive Syndrome (1998)

(1998). The Development of an Ecologically Valid Test for Assessing Patients with a Dysexecutive Syndrome. Neuropsychological Rehabilitation: Vol. 8, Assessment of Attention and Executive Function. Guest Editor: J. Crawford, pp. 213-228.
Brief but Efficient: Acute HIV Infection and the Sexual Transmission of HIV (2004)

Empirical biological data strongly support the hypothesis that sexual transmission by acutely infected individuals has a disproportionate effect on the spread of HIV-1 infection. Acute hyperinfectiousness may, in part, explain the current pandemic in heterosexual individuals.
GM-CSF co-expressing DNA/MVA vaccine, prevention of acquisition by two series of SIVE660 challenges followed by a series of SIV251 challenges (2012)

Methods Following the initial 12 challenges, 5 uninfected rhesus were monitored for one year, boosted with 1x10 pfu of MVA/SIV239, and re-challenged 6 months later with 12 weekly rectal doses of SIVE660. The resulting four uninfected macaques were held an additional 6 months and challenged with 12 weekly rectal doses of SIV251. Avidity of Env-specific IgG was determined using a NaSCN elution ELISA. Per exposure efficacy was estimated using a leaky effects model.