gebhart/patrepeval huggingface dataset:
BIORESIST: a lithographic approach for the patterning of cells in tissue engineering applications (2004)

Due to the involvement of organic solvents and strong bases in the pattern development process, conventional lithography, a technique that has been well-developed and widely used in the semiconductor industry, is not suitable for direct cell and protein patterning. In order to address this issue, we recently developed a biocompatible chemically amplified photoresist, BIORESIST, with which patterns can be generated without involving any harsh chemical treatment. Such a BIORESIST contains tert-butoxycarbonyl (<i>t</i>-BOC) protecting groups. <i>In vitro</i> cell culture study has shown that the <i>t</i>-BOC protected BIORESIST and its carboxyl-substituted counter-part interact very differently with cells. The former is non-cell adhesive, while the latter not only keeps cell attached, but also supports cell proliferation. This unique property prompted us to generate patterns (25 &mu;m L/S) with this BIORESIST with no wet development involved. Rat fibroblast cells were cultured on the patterned surfaces. The results demonstrated that cells were strongly aligned along the patterns and attached exclusively to the adhesive region as opposed to a random appearance on the plain control surface after 24 hr of incubation. With this BIORESIST, the scalability aspect of conventional lithography could be well applied for cell patterning.
Mixed sparse representation for approximated observation-based compressed sensing radar imaging (2018)

Recently, compressed sensing (CS) has been applied in synthetic aperture radar (SAR). A framework of mixed sparse representation (MSR) has been proposed for reconstructing SAR images due to the complicated ground features. The existing method decomposes the image into the point and smooth components, where the sparse constraint is directly applied to the smooth components. This makes it difficult to tackle the complex-valued SAR images, since the phase angles of SAR images are always stochastic. A magnitude-phase separation MSR method is proposed for CS-SAR imaging based on approximated observation. Compared to the existing method, the proposed method has better reconstruction ability, because it only imposes the sparse constraint on the magnitude of the smooth components, and therefore, the phase angles are still stochastic. Furthermore, owing to the inherent low memory requirement of approximated observation, the proposed method requires much less memory cost. In the simulation and experimental results, the proposed method deals with the complex-valued SAR images effectively and demonstrates superior performance over the chirp scaling algorithm and the existing MSR method.
Fermentation (1954)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFermentationDavid Perlman and Charles KrollCite this: Ind. Eng. Chem. 1954, 46, 9, 1809–1826Publication Date (Print):September 1, 1954Publication History Published online1 May 2002Published inissue 1 September 1954https://doi.org/10.1021/ie50537a029Request reuse permissionsArticle Views196Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (3 MB) Get e-Alerts
Functional activity of vasopressin analog desglycinamide-arginine-vasopressin (2006)

Original and published data on the functional activity of neurohypophyseal hormone vasopressin and its analog DGAVP were analyzed with a particular focus on the pattern of the peptide effect on the hemostatic system. The effects of the natural hormone and its synthetic analog on some indices of coagulation and fibrinolysis were compared. The effects of the peptides on the behavioral responses as well as on memory processes of animals are analyzed.
Data Validation and Interpretation (2007)

Abstract In this chapter, the technical analytical value of a test result is distinguished from the diagnostic value. The analytical procedure is validated technically in order to provide information on the technical uncertainty of a test result. This validation process follows globally accepted protocols and recommendations, which are cited in this chapter (Internet links are given). The diagnostic value relies primarily on biological uncertainties, on the position of a cutoff limit for two populations from different sources to distinguish between the test results and on other factors, which are described systematically. Models and discussions about how to interpret data are primarily found in the literature, which deals with diagnostic screening tests for medical applications. However, the rules are generally valid in all fields of data interpretation in analytical chemistry. This is the message given in this chapter.
Real-Time Simulation of Electrical Vehicle Motor Drives on a PC Cluster (2003)

This paper presents a real-time motor drive simulator capable to accurately simulate a double IGBT bridge inverter connected to an induction motor through an interphase transformer. The simulator also includes a DClink model with regeneration capability and two choppers. The paper will detail the implementation of the model and simulation results and timing. The whole system, with external I/O IGBT fiber optic gate signals, executes in real-time at 80 µs time step under the RT-Lab real-time distributed simulation software on a PCcluster composed of 3 Pentium processors running at 1 GHz. The same model, but this time with only one bridge and no interphase transformer, runs in real-time at 65 µs time step.
Development of the murine and human immune system: differential effects of immunotoxicants depend on time of exposure. (2000)

Fetal and early postnatal life represent critical periods in vertebrate immune system development. Disruption of such development by perinatal immunotoxic chemical exposure has been widely described in experimental animal models. The resultant inhibited postnatal immune responses in such animals are often more dramatic and persistent than those after exposure during adult life. Further, recent reports suggest that prenatal exposure to immunotoxicants may exacerbate postnatal aberrant immune responses (e.g., hypersensitivity disorders and autoimmune disease) in genetically predisposed rodents. Limited information is available regarding the possibility of inhibited postnatal immune capacity in humans as a result of developmental immunotoxicant exposure. The multifactorial nature of hypersensitivity and autoimmune responses will further complicate the elucidation of possible relationships between chemical exposure during ontogeny of the human immune system and immune-mediated disease later in life. Taken together, however, the available animal data suggest the potential for altered postnatal immune function in humans exposed to immunotoxicants (e.g., environmental chemicals and therapeutic agents) during fetal and/or early postnatal life.
Extraction de composants purs et démélange linéaire bayésiens en imagerie hyperspectrale (2009)

International audience
Towards a fracture criterion based on time-scale analysis (2009)

Dans le cadre de la reproduction d’accident&#13;\n sur sujet humain post mortem il est souvent impossible de déterminer l’instant&#13;\n d’apparition d’une lésion. L'objectif de l’étude est de caractériser les signaux&#13;\n transitoires correspondant aux fractures à partir d’enregistrements piezoelectriques&#13;\n afin de pister leur apparition à l’aide d’une analyse temps fréquence. Les résultats&#13;\n présentent la partie préliminaire de l’étude sur le thorax et les fractures de&#13;\n cote.
Complexity scalable audio coding algorithm based on wavelet packet decomposition (2002)

In this paper, a complexity scalable audio coding algorithm based on wavelet packet decomposition is proposed. The incomplete wavelet packet decomposition with the property of complexity scalability to the signals is described in this paper. The zerotree coding of the coefficients is implemented which uses the characteristics of human ears and the self-similarity among different subbands wavelet coefficients. This algorithm cannot only be used to achieve transparent quality reconstruction audio at low bit rate, but also enable to support complexity scalable coding and multirate scalable coding. Audio encoding and decoding can be realized in real-time utilizing this algorithm on computers with different levels of computational power. The experimental results indicate that this algorithm is of practical value to the real-time multimedia applications.
Impact Factor and Other Journal Metrics (2013)

I have always wondered whether the impact factor was a reasonable metric to describe the journal performance of Optical Engineering. This month, I have had some pretty good discussions with SPIE staff and some of the other SPIE journal editors about the topic.
Design of a role-based trust-management framework (2005)

We introduce the RT framework, a family of role-based trust management languages for representing policies and credentials in distributed authorization. RT combines the strengths of role-based access control and trust-management systems and is especially suitable for attribute-based access control. Using a few simple credential forms, RT provides localized authority over roles, delegation in role definition, linked roles, and parameterized roles. RT also introduces manifold roles, which can be used to express threshold and separation-of-duty policies, and delegation of role activations. We formally define the semantics of credentials in the RT framework by presenting a translation from credentials to Datalog rules. This translation also shows that this semantics is algorithmically tractable.
Sequence analysis of canine LINE-1 elements and p53 gene in canine transmissible venereal tumor (2002)

LINEs (long interspersed nuclear elements or long interspersed repeated DNA elements) contains two open reading frames (ORFs), ORF1 and ORF2. We analysed the ORF2 located in the 5' region to the first exon of oncogene c-myc in canine transmissible venereal tumor (TVT) cell. We also showed the transcription activation was induced by this TVT-LINE sequence using CAT assay. To identify the mutation of tumor suppressor gene, sequence analysis of p53 from TVT cell was performed. We identified the point mutation of 964 nucleotide (T-C) resulting in the change of amino acid (Phe-Ser) of p53 tumor suppressor protein.
Performance of Thermal Swing Honeycomb VOC Concentrators. (1998)

A honeycomb laminate was formed with ceramic fiber paper and was then heat-treated. It was impregnated with a dispersion of high silica zeolite, inorganic binder and silica sol, and was dried to get a honeycomb rotor of adsorbent for the VOC concentrating rotor.The removal efficiency of the rotors, which were installed in a testing unit and user’s actual units, was examined for several variables, such as the rotation speed, the face velocity of desorption air, the effect of VOC concentration ratio, f, on the fractional removal of the rotors etc. The result showed that the optimal rotation speed of the VOC concentrating rotor was expressed by a nondimensional number, UR(f•noptL = 450, and that the rotor removed more than 90% of the VOCs laden in the process gas stream with its concentration ratio of 10 times in the desorption gas stream with the suitable combinations of the variables mentioned above.
Long-term outcomes with neoadjuvant chemotherapy with or without stereotactic body radiation therapy in patients with borderline resectable and locally advanced pancreatic adenocarcinoma. (2021)

443 Background: Patients (pts) withborderline resectable pancreatic cancer (BRPC) or locally advanced pancreatic cancer (LAPC) are at high risk of margin positive resection with upfront surgery. Pre-operative stereotactic body radiation therapy (SBRT) may help sterilize vascular margins, but its additive benefit beyond multi-agent chemotherapy (CTX) is unclear. We report on long-term outcomes from a high-volume institution of BRPC/LAPC pts who were reviewed by a multidisciplinary team and explored after either multi-agent CTX alone or multi-agent CTX followed by SBRT. Methods: Consecutive BRPC/LAPC pts diagnosed 2011-2016 who underwent resection following CTX alone or CTX followed by 5-fraction SBRT (CTX-SBRT) were retrospectively reviewed. Baseline demographic, clinical, and treatment factors were compared between cohorts, and survival analysis was conducted to compare pathologic and survival outcomes. Results: Of 199 pts, 77 received CTX alone and 122 received CTX-SBRT. There was no significant difference between cohorts in age, gender, performance status, tumor location, CA19-9 at diagnosis, or post-CTX CA19-9 values (all p &gt; 0.05). The CTX-SBRT cohort had a higher proportion of pts with LAPC as compared to the CTX cohort (53% vs 22%, p&lt; 0.001). Modified FOLFIRINOX (mFFX) was administered to 55% of pts, while 70% of pts received either mFFX or gemcitabine/abraxane, with no difference between cohorts. Duration of CTX was longer in the CTX-SBRT cohort as compared to the CTX cohort (median 4.6 vs. 2.9 mos, p= 0.03), but adjuvant CTX was not given as often in the CTX-SBRT arm (60.4% vs. 86.4%, p= &lt; 0.001). Notably, 30% of the CTX cohort also received adjuvant chemoradiation. Pathologic response was significantly improved in the CTX-SBRT cohort vs the CTX cohort, specifically negative margins (92% vs 70%, p&lt; 0.001), node negative (59% vs. 42%, p&lt; 0.001), and pathologic complete response (7% vs. 0%, p= 0.02). On multivariable analysis, after controlling for prognostic factors, CTX-SBRT remained significantly associated with margin negative resection ( p&lt; 0.001). Despite having more advanced stage and less adjuvant therapy administration in the CTX-SBRT cohort, there was no significant difference in overall survival after surgery (median OS: 24.6 vs. 22.2 mo, p= 0.79), local progression free survival (14.0 vs. 13.6 mo, p= 0.33), or distant metastasis free survival (16.4 vs. 11.8 mo, p= 0.33). Conclusions: Despite more advanced disease at presentation, BRPC/LAPC pts treated with CTX-SBRT were more likely to undergo margin negative resection and experienced similar survival outcomes, as compared to CTX alone. More data are needed to refine which patients benefit from neoadjuvant SBRT and how RT administration can be optimized to impact survival outcomes.
Improving Grid Fault Tolerance by Optimal Control of FACTS Devices (2007)

One of the most promising applications of the family of power electronic devices called Flexible AC Transmission System devices is to better regulate power flow in transmission grids. In particular, the Unified Power Flow Controller (UPFC) is the best choice for complete power flow control. By selecting proper installation locations and control techniques, UPFCs may be able to prevent the “domino effect, ” where a single fault leads to a widespread blackout. Due to installation costs, it is hoped that only a small number of devices will be needed to effectively regulate a large grid, however, selecting the optimal number of devices, identifying the best possible installation locations, and finding a technique for coordinated control of these device are still active areas of research. In this paper we provide empirical evidence that common optimization techniques may be used to identify control settings for UPFCs. The evidence indicates that the optimization techniques lend themselves to real-time use, as well as use during the planning phase to identify the best possible installation locations for UPFCs.
Broadband HBT Doherty Power Amplifiers for Handset Applications (2010)

A Doherty power amplifier for IEEE 802.16e mobile worldwide interoperability for microwave access (m-WiMAX) is fully integrated on a 1.2 × 1.2 × mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> die using a 2-μm InGaP/GaAs hetero-junction bipolar transistor (HBT) process. The direct input power dividing technique is employed on the chip. Broadband input and output matching techniques are used for broadband Doherty operation, and their effects are analyzed. A peaking amplifier 1.5 times larger than a carrier amplifier delivers high efficiency for m-WiMAX signal with a 9.6-dB crest factor and an 8.75-MHz bandwidth (BW). The PA with a supply voltage of 3.4 V has an EVM of 2.3% and a PAE of 31.5% at an output power of 24.75 dBm as well as an operating frequency of 2.6 GHz. A PAE over 30.3% and an output power of greater than 24.6 dBm with an EVM less than 3.15% and a gain variation of 0.2 dB are achieved across 2.5-2.7 GHz without any assisting linearization technique. After compensating AM-AM and AM-PM nonlinearity using a digital feedback predistortion algorithm, the PA exhibits a PAE of over 27% and an output power of over 23.6 dBm across 2.2-2.8 GHz while maintaining an EVM below 2.7%.
Hybrid Pre-Coding Based on Minimum SMSE Considering Insertion Loss in mmWave Communications (2019)

Hybrid pre-coding design is a promising research direction in large antenna array millimeter wave (mmWave) systems. The insertion loss is an inherent and significant feature of hybrid pre-coding, resulting in lower energy efficiency and inferior bit error rate (BER) performance. This paper takes the minimum sum-mean-square-error (Min-SMSE) considering the insertion loss as the optimization objective function, which aims at increasing the sum-rate and improving the BER performance. Then a hybrid pre-coding is designed based on this criterion with an adaptive overlapped subarray (OSA) architecture. It is proved that the optimization problem is non-convex. Thus, we decompose the optimization problem into two sub-optimum ones. One is to design the digital pre-coding based on the Min-SMSE criterion under the equivalent channel condition. The other one is to design the analog pre-coding based on the simplified Min-SMSE with the insertion loss objective function. Theoretical analyses of the proposed scheme are conducted, including the upper bound of the average BER, the lower bound of the average sum-rate, and the computational complexity. Simulation results show that our proposed scheme outperforms three representative hybrid pre-coding schemes with different architectures in both BER and sum-rate, when the numbers of the phase shifters and combiners are relatively small.
Erkennbarkeit und Vermeidbarkeit von ungebremsten Motorrad-Kurvenunfällen (2021)

In den letzten 15 Jahren sank die Zahl der Getöteten im Straßenverkehr sehr stark und erreichte seit 2004 stets neue Tiefststände – die Zahl der getöteten Zweiradfahrer hingegen stagniert seit einigen Jahren auf ihrem Niveau. Der Fragestellung, ob und wenn ja wie Fahrdynamikregelsysteme auch für Motorräder darstellbar sind und einen Effekt der Unfallzahlensenkung hervorrufen können, wird in dieser Arbeit nachgegangen. Aus einer auf Expertenbefragung und Auswertung einer Unfalldatenbank basierenden Analyse des Unfallgeschehens von Motorrädern leiten sich ungebremste Kurvenunfälle als potentiell vermeidbar durch zukünftige Fahrdynamikregelsysteme ab. Für diese Unfallklassen von Motorrädern sind keine Methoden der Erkennung und Beeinflussung bekannt. Die beiden denkbaren Grundszenarien ungebremster Kurvenunfälle – Erreichen der Kraftschlussgrenze durch negativen Reibwertsprung und durch Erhöhen des Kraftschlussbedarfs – wurden mittels Fahrversuch hinsichtlich besonderer Erkennungsmerkmale untersucht. Spätestens mit Beginn des Gleitens an beiden Rädern zeigt sich in allen nachgestellten Unfällen eine kurveneindrehende Schwimmwinkelgeschwindigkeit (oder auch Gierratenüberhöhung). Zusätzlich rollt („kippt“) das Fahrzeug zum Kurveninneren hin. Die Auswertung der Schwimmwinkelgeschwindigkeit erweist sich als geeignetes Kriterium zur Erkennung dieser Fahrsituationen, das auch bei hochdynamischen Fahrmanövern wie VDA-Spurwechsel und rennstreckenähnlicher Fahrten eine hinreichend hohe Erkennungsschwelle zur Vermeidung von „false positive“-Fehlern besitzt. Zur Stabilisierung der Rollbewegung ist eine Erhöhung von Seitenkraft oder Rollmoment erforderlich. Erhöhen des Rollmomentes ist physikalisch erreichbar durch Verwendung von Stabilisierungskreiseln. Technisch anwendbar für typische Einspurfahrzeuge ist diese Methode nicht, dazu sind die Energien und Massen zu groß. Das Erhöhen der Radlast durch aktive Fahrwerke beansprucht mindestens in gleichem Maße den Querkraftschluss und kann daher auch nicht zur Stabilisierung verwendet werden. Da die Gierstabilisierung mit einer Beeinflussung der Seitenkraftdifferenz auskommt, ist eine Beeinflussung des Gierdrehung durch Manipulation von Reifenlängsschlupf oder Schräglauf mit dem Ziel einer Schwimmwinkelbegrenzung. Mit dieser Methode können High-sider-Unfälle (wie sie bei Reibwertsprüngen hoch-niedrig-hoch entstehen) potentiell vermieden werden. Diese Unfälle sind jedoch nur eine Teilmenge der avisierten 4-8% der Motorradunfälle.
Treatment of neurogenic scapular winging: a systematic review on outcomes after nonsurgical management and tendon transfer surgery (2022)

A substantial part of nonsurgically managed patients with scapular winging seem to have persistent complaints, which should be part of the information provided to patients. Data pooling demonstrated significant improvements in shoulder function, pain scores, and shoulder scores after tendon transfer surgery, but higher quality evidence is needed to allow for more robust recommendations and guide clinical decision-making on when to perform such functional surgery.
Harmonic contents in induced EMF and Electromagnetic Torque in mass produced sinusoidal PM brushless machines (2012)

This research provides a detailed finding of the harmonic contents in the induced voltage and developed torque in permanent magnet synchronous motors due to electromagnetic origins. Two fractional slot PM topologies are investigated to analyze the harmonic contents that is influenced by motor slot/pole and winding configurations. The research also points out the various sources responsible for producing harmonics through mathematical models as they appear in induced voltage and developed torque. The theory is presented by analytical formulas and finite element based modeling. Both analytical and FE based modeling are verified by building some motors of both topologies. Various practical build issues originated from both rotor and stator such as magnet placement and property variations and winding arrangements are considered. The research shows the sensitivities of different motor topologies under manufacturing tolerances for mass production.