gebhart/patrepeval huggingface dataset:
Design of an optimal controller for a discrete-time system subject to previewable demand (1985)

This paper is concerned with a method of designing a type one servomechanism for a discrete-time system subject to a time-varying demand and an unmeasurable constant disturbance. It is assumed that the time-varying demand is previewable in the sense that some finite future as well as present and past values of the demands are available at each time. A controller with state feedback plus integral and preview actions is derived by applying a linear quadratic integral (LQI) technique due to Tomizuka and Rosenthal (1979). It is shown under the stabilizability and detectability conditions that the closed-loop system achieves a complete regulation in the presence of small perturbations in system parameters, eliminating the effect of disturbance. An example of power plant control is presented to show the flexibility of the design method and the effectiveness of the preview action for improving the transient responses of the closed-loop system.
LRP5 regulates human body fat distribution by modulating adipose progenitor biology in a dose- and depot-specific fashion (2015)

Summary Common variants in WNT pathway genes have been associated with bone mass and fat distribution, the latter predicting diabetes and cardiovascular disease risk. Rare mutations in the WNT co-receptors LRP5 and LRP6 are similarly associated with bone and cardiometabolic disorders. We investigated the role of LRP5 in human adipose tissue. Subjects with gain-of-function LRP5 mutations and high bone mass had enhanced lower-body fat accumulation. Reciprocally, a low bone mineral density-associated common LRP5 allele correlated with increased abdominal adiposity. Ex vivo LRP5 expression was higher in abdominal versus gluteal adipocyte progenitors. Equivalent knockdown of LRP5 in both progenitor types dose-dependently impaired β-catenin signaling and led to distinct biological outcomes: diminished gluteal and enhanced abdominal adipogenesis. These data highlight how depot differences in WNT/β-catenin pathway activity modulate human fat distribution via effects on adipocyte progenitor biology. They also identify LRP5 as a potential pharmacologic target for the treatment of cardiometabolic disorders. © 2015 The Authors.
Self-assembling of InAs nanocrystals on GaAs: The effect of electronic coupling and embedded gold nanoparticles on the photoluminescence (2006)

In As ∕ Zn Se core/shell nanoparticles (NP) were self-assembled on GaAs substrates using different organic molecules of varying length and properties as linkers. The molecules provide control over the coupling and tunneling properties between the substrate and the nanocrystals. By coadsorbing of gold NP on the GaAs substrate, enhancement of the photoluminescence from the InAs NP was achieved. The enhancement factor was found to depend on the properties of the organic linkers.
Highly Transparent, Flexible, and Thermally Stable Superhydrophobic ORMOSIL Aerogel Thin Films (2011)

We report preparation of highly transparent, flexible, and thermally stable superhydrophobic organically modified silica (ORMOSIL) aerogel thin films from colloidal dispersions at ambient conditions. The prepared dispersions are suitable for large area processing with ease of coating and being directly applicable without requiring any pre- or post-treatment on a variety of surfaces including glass, wood, and plastics. ORMOSIL films exhibit and retain superhydrophobic behavior up to 500 °C and even on bent flexible substrates. The surface of the films can be converted from superhydrophobic (contact angle of 179.9°) to superhydrophilic (contact angle of <5°) by calcination at high temperatures. The wettability of the coatings can be changed by tuning the calcination temperature and duration. The prepared films also exhibit low refractive index and high porosity making them suitable as multifunctional coatings for many application fields including solar cells, flexible electronics, and lab on papers.
The spectrum of cutaneous lesions in rheumatoid arthritis: a clinical and pathological study of 43 patients (2003)

The cutaneous manifestations of RA are varied and encompass a number of entities, some of which define the dominant clinical features, such as the rheumatoid papule or subcutaneous cords, while others allude to the histopathology, i.e. rheumatoid neutrophilic dermatosis. We propose a more simplified classification scheme using the adjectival modifiers of "rheumatoid-associated" and then further categorizing the lesion according to the dominant reaction pattern. Three principal reaction patterns are recognized, namely extravascular palisading granulomatous inflammation, interstitial and/or subcuticular neutrophilia and active vasculopathy encompassing lymphocyte-dominant, neutrophil-rich and granulomatous vasculitis. In most cases, an overlap of the three reaction patterns is seen. Co-factors for the vascular injury that we believe are integral to the skin lesions of RA include RF, anti-endothelial antibodies of IgA class, anti-Ro and anticardiolipin antibodies.
Wnt/β-catenin signaling pathway in cutaneous tumors: an update (2011)

The abnormal activation of Wnt/β-catenin signaling pathway is usually and closely related to the occurrence and development of cutaneous tumors.There are various factors causing the abnormality of this pathway, such as deregulated expression of secreted Wnt protein, mutations of proteins involved in this pathway or regulatory molecules in bypass pathway, viral infection, interaction with other pathways, and so on.In addition, the tumorigenic mechanisms of this pathway and its biologcal effects on tumors are considered to be tissue-specific.However, the types and tissue origins of cutaneous tumors are various.Therefore, exploring the disparities and tissue specificity of Wnt pathway in cutaneous tumors will provide a guide to the targeted therapy of tumors.

Key words: 
Skin neoplasms; Beta catenin; Wnt proteins; Signal transduction
Texture-Independent Long-Term Tracking Using Virtual Corners (2015)

Long-term tracking of an object, given only a single instance in an initial frame, remains an open problem. We propose a visual tracking algorithm, robust to many of the difficulties that often occur in real-world scenes. Correspondences of edge-based features are used, to overcome the reliance on the texture of the tracked object and improve invariance to lighting. Furthermore, we address long-term stability, enabling the tracker to recover from drift and to provide redetection following object disappearance or occlusion. The two-module principle is similar to the successful state-of-the-art long-term TLD tracker; however, our approach offers better performance in benchmarks and extends to cases of low-textured objects. This becomes obvious in cases of plain objects with no texture at all, where the edge-based approach proves the most beneficial. We perform several different experiments to validate the proposed method. First, results on short-term sequences show the performance of tracking challenging (low textured and/or transparent) objects that represent failure cases for competing the state-of-the-art approaches. Second, long sequences are tracked, including one of almost 30 000 frames, which, to the best of our knowledge, is the longest tracking sequence reported to date. This tests the redetection and drift resistance properties of the tracker. Finally, we report the results of the proposed tracker on the VOT Challenge 2013 and 2014 data sets as well as on the VTB1.0 benchmark, and we show relative performance of the tracker compared with its competitors. All the results are comparable with the state of the art on sequences with textured objects and superior on non-textured objects. The new annotated sequences are made publicly available.
Spindle Cell Carcinoma Arising in a Mammary Hamartoma (2022)

乳腺の紡錘細胞癌は全乳癌の0.1～0.2％と稀で，化学療法抵抗性や早期遠隔再発などで予後不良とする報告が多い．取扱い規約は比較的予後の良い線維腫症様化生癌も含めているが，WHO分類は両者を区別している．乳腺過誤腫は「breast in breast」と称され，乳腺良性腫瘍の5％未満の稀な腫瘍である．過誤腫に発生した乳癌の報告は24例と少なく，組織型は乳管癌16（浸潤13，非浸潤3），小葉癌6（浸潤4，非浸潤2），両者の併存1で，特殊型は粘液癌の1例のみであった．
Enabling services in broadband access (2007)

The paper describes functions to enable services over a broadband access network. A service plane is introduced to embed such functions in the access network. Examples for multimedia delivery are given. (2 pages)
IETool y Cmap Tools: Ambiente interactivo para el desarrollo de habilidades argumentativas (2003)

Este articulo presenta las experiencias adquiridas en tres anos de desarrollo y uso de Interactive Environtment Tool (IETool) y su interaccion con Cmap Tools, del Institute for Human and Machine Cognition, en dos cursos de pregrado en Ingenieria de Sistemas de la Universidad EAFIT. IETool es una plataforma tipo foro donde se trabajan en forma asincronica interacciones entre los miembros de un grupo de personas (estudiantes y profesores) alrededor de una actividades propuestas de aprendizaje. Estas actividades tienen como objetivo el fomentar el contraste de las ideas, la confrontacion, el consenso, el control y la autorregulacion de los diferentes procesos por parte de los integrantes; ademas, exige la produccion de relaciones organizadas entre los que aprenden, los que ensenan y los objetos de conocimiento, de forma que se pueda asegurar el reconocimiento de las habilidades que se ponen al servicio del aprendizaje a partir de los motivos, planes, acciones, operaciones, control y regulacion sobre la actividad. El programa Cmap Tools se utilizo como herramienta de desarrollo de mapas conceptuales que se usaron como organizadores y representadores del conocimiento, que facilitaban a los estudiantes identificar los conceptos claves a comprender durante el desarrollo del curso.
Cone-beam reconstruction from a variable-radius, planar source trajectory (2009)

In this paper, we present a practical Feldkamp-like algorithm for flat-panel cone-beam reconstruction from a planar source trajectory with varying radius. Along with the reconstruction, our algorithm simultaneously recovers the shape of the field-of-view, which can be of complex structure in variable-radius geometries. Numerical results of our algorithm are presented for a short-scan rectangular acquisition geometry as well a full-scan flower-shape geometry. Evaluation was carried out using simulated data of the FORBILD head phantom.
RNA Sequencing Analysis of Intracranial Aneurysm Walls Reveals Involvement of Lysosomes and Immunoglobulins in Rupture (2016)

For rupture of intracranial aneurysms, we identified the lysosome pathway as a new pathway and found further evidence for the role of the immune response. Our results also point toward a role for immunoglobulins in the pathogenesis of aneurysms. Immune-modifying drugs are, therefore, interesting candidate treatment strategies in the prevention of aneurysm development and rupture.
Abstract 11974: The Prognosis of Patients With the Long-Term Cardiac Rehabilitation: The Large Cohort Study of Long-Term Cardiac Rehabilitation Among Patients With Cardiovascular Disease (L-CREAM Study) (2018)

Introduction: The cardiac rehabilitation (CR) is strongly recommended for patients with cardiovascular diseases, but there are few studies of the long-term exercise training and no large-scale cons...
Medium Voltage DC Bus Enabled by Series Connection of SiC Mosfet Based Three Port DC-DC Converters (2019)

This paper presents development of Medium Voltage(MV) DC bus using series connection of Modular DC-DC Converter blocks. The MVDC bus is developed using Three Port Triple Active Bridge(TAB) DC-DC converter, which integrate Renewable Energy Sources(RES) and Energy Storages(ES). The TAB DC-DC converter units are three port high frequency transformer isolated phase shifted converters which integrate RES and ES with an output dc bus. Multiple of this DC-DC converter output dc buses can be connected in series to obtain a Medium Voltage DC Bus. The three port TAB converters for this series connection of converters, use 1200V & 1700V SiC Mosfets as switching devices with a three port high frequency transformer providing galvanic isolation among the three ports. In this paper, two laboratory prototypes of the three port TAB converters are connected in series to demonstrate MVDC bus(>2kV). Three port TAB converter, Gate Drivers for TAB converters, Three Port High Frequency transformer, along with independent power & voltage control for three port TAB Converter is discussed here in this paper with experimental verification.
Sensor management for PRF selection in the track-before-detect context (2012)

We consider the pulse repetition frequency (PRF) selection problem for target tracking in the context of track-before-detect. Two sensor management criteria are proposed for solving the PRF selection problem. From the information theoretic class, a Kullback-Leibler divergence based criterion is employed and from the task based class, a criterion that is based on the covariance matrix of the posterior density. The proposed sensor management criteria succeed in resolving the ambiguities, avoid choosing a PRF that would place the target in a blind zone and they both produce an unexpected but interesting aspect in the results. That is, they can prevent ambiguities from reappearing due to the motion model without being explicitly designed to handle this unpredicted problem.
Bit Error Probability of SM-MIMO Over Generalized Fading Channels (2012)

In this paper, we study the performance of spatial modulation (SM) multiple-input–multiple-output (MIMO) wireless systems over generic fading channels. More precisely, a comprehensive analytical framework to compute the average bit error probability (ABEP) is introduced, which can be used for any MIMO setup, for arbitrary correlated fading channels, and for generic modulation schemes. It is shown that, when compared with state-of-the-art literature, our framework 1) has more general applicability over generalized fading channels, 2) is, in general, more accurate as it exploits an improved union-bound method, and, 3) more importantly, clearly highlights interesting fundamental trends about the performance of SM, which are difficult to capture with available frameworks. For example, by focusing on the canonical reference scenario with independent identically distributed Rayleigh fading, we introduce very simple formulas that yield insightful design information on the optimal modulation scheme to be used for the signal constellation diagram, as well as highlight the different roles played by the bit mapping on the signal and spatial constellation diagrams. Numerical results show that, for many MIMO setups, SM with phase-shift-keying (PSK) modulation outperforms SM with quadrature-amplitude modulation (QAM), which is a result never reported in the literature. In addition, by exploiting asymptotic analysis, closed-form formulas of the performance gain of SM over other single-antenna transmission technologies are provided. Numerical results show that SM can outperform many single-antenna systems and that, for any transmission rate, there is an optimal allocation of the information bits onto spatial and signal constellation diagrams. Furthermore, by focusing on the Nakagami- <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">$m$</tex></formula> fading scenario with generically correlated fading, we show that fading severity plays a very important role in determining the diversity gain of SM. In particular, the performance gain over single-antenna systems increases for fading channels less severe than Rayleigh fading, whereas it gets smaller for more severe fading channels. In addition, it is shown that the impact of fading correlation at the transmitter is reduced for less severe fading. Finally, analytical frameworks and claims are substantiated through extensive Monte Carlo simulations.
A Digital Signal Processing Instrument for Real-Time Phase Noise Measurement (2008)

A digital-signal-processing-based instrument for phase noise measurement on sinusoidal signals is described. It incorporates a special hardware architecture, which is made up of a core digital signal processor that is connected to a data acquisition board, and takes advantage of a new measurement procedure based on a quadrature demodulation scheme, which has been proposed by the authors. Thanks to an optimized implementation of this procedure, the instrument exploits all its hardware resources to achieve high performance and real-time operation. For input frequencies of up to some hundreds of kilohertz, the instrument proves to be capable both of updating phase noise power spectrum while seamlessly capturing the analyzed signal into its memory and of granting frequency resolution as good as a few units of hertz.
Test Study on Dynamic Mechanical Property of Jointed Rock Mass (2013)

Failure modes of jointed rock mass with different joint dip angle, joint center continuity degree, joint sets, load strain ratio and joint filling width under SHPB test are studied with model tests. The results show that failure modes and dynamic strength of jointed rock mass are much related to joint geometry. To rock mass with a single joint, its strength and failure mode are greatly controlled by the joint dip angle. The dynamic strength of the samples with joint dip angle 0° and 90°, whose failure modes are both tensile failure, is 90% and 71% of that of intact one, respectively. The dynamic strength of the samples with joint dip angle 60° is nearly zero. The dynamic strength of the samples with joint dip angle 30° and 45°, whose failure modes are mainly shear failure with partly tensile failure, is 50% and 18% of that of intact ones, respectively. The dynamic strength of the samples with 1/4, 1/2 and 4/5 joint center continuity degree is 95%, 74% and 28% of that of intact one, respectively. The dynamic strength of the samples with 1, 2 and 3 sets of joints is 54%, 23% and 10% of that of intact one, respectively. The dynamic strength of the intact and jointed samples both increases with load strain ratio, and the sensitivity to load strain ratio of the former is much higher than that of the latter, whose failure mode becomes more complicated accordingly. With increase of joint fillings width, the samples dynamic strength decreases gradually, but its failure mode does not change.
Self-propagating high-temperature synthesis of nano-TiC x particles with different shapes by using carbon nano-tube as C source (2011)

With using the carbon nano-tube (CNT) of high chemical activity, nano-TiCx particles with different growth shapes were synthesized through the self-propagating high temperature in the 80 wt.% metal (Cu, Al, and Fe)-Ti-CNT systems. The growth shapes of the TiCx particles are mainly octahedron in the Cu- and Al-Ti-CNT systems, while mainly cube- and sphere-like in the Fe-Ti-CNT system.
Longitudinal neuropsychological outcomes in treatment-resistant depression following bed nucleus of the stria terminalis-area deep brain stimulation: a case review (2018)

Studies have demonstrated the effectiveness of deep brain stimulation (DBS) as a treatment modality for psychiatric conditions. We present a case reviewing the longitudinal neuropsychological performance outcomes following bed nucleus of the stria terminalis-area (BNST) DBS in a patient with treatment-resistant depression (TRD). The cognitive safety of DBS is well documented for various targets, however cognitive outcomes of BNST-area DBS have not been extensively reported for patients with TRD. Neuropsychological assessment was conducted pre- and post-DBS. Twelve months following DBS, augmented general cognitive performance was observed with significant changes in specific domains.
A POÉTICA VISUAL DE PHILIPPE GENTY (2017)

Philippe Genty iniciou a sua carreira como marionetista, nos anos 60, na Franca. Com o passar do tempo, sob influencia da psicanalise e do contato com outras praticas teatrais e artisticas, o seu trabalho evoluiu para um teatro pautado na imagem e na materialidade: com formacao em design grafico e estabelecendo um constante dialogo com outras linguagens, Genty concebe espetaculos em que a presenca humana, a luz, a musica, a danca, o espaco, a materia (papeis, tecidos, plasticos, etc.), assim como objetos, manequins e marionetes, se somam para criar poesias cenicas autorais e autobiograficas. A presente pesquisa de doutoramento analisa a poetica visual de Philippe Genty, mergulhando nas entrelinhas de um processo poetico-pessoal e analisado suas tessituras dramaturgicas, por meio de um conjunto de obras que datam mais de 50 anos de atividade artistica. Os materiais utilizados para a pesquisa, alem de textos teoricos, compoem-se de videos de espetaculos, documentarios, projetos de espetaculos escritos por Genty, textos autobiograficos, criticas de espetaculos, fotografias e entrevistas realizadas em pesquisa de campo no ano de 2016, na Franca. Um dos pontos discutidos na tese e o elemento humano como materialidade da cena - entendido a partir de uma concepcao antes plastica do que dramatica – e como esse elemento pode perturbar o espaco da representacao, uma vez que, nos espetaculos analisados, ocorre um deslocamento de funcao e significado da presenca humana: Genty dilui o carater de individualidade, multiplicando-o em duplos que ora sao manequins, ora sao personagens hibridos – humanos travestidos de manequins, ora sao individuos duplicados – atuantes travestidos como duplos, colocando o humano em relacao de igualdade com os outros elementos da representacao.
Drug-Loaded and Superparamagnetic Iron Oxide Nanoparticle Surface-Embedded Amphiphilic Block Copolymer Micelles for Integrated Chemotherapeutic Drug Delivery and MR Imaging (2011)

We report on the fabrication of organic/inorganic hybrid micelles of amphiphilic block copolymers physically encapsulated with hydrophobic drugs within micellar cores and stably embedded with superparamagnetic iron oxide (SPIO) nanoparticles within hydrophilic coronas, which possess integrated functions of chemotherapeutic drug delivery and magnetic resonance (MR) imaging contrast enhancement. Poly(ε-caprolactone)-b-poly(glycerol monomethacrylate), PCL-b-PGMA, and PCL-b-P(OEGMA-co-FA) amphiphilic block copolymers were synthesized at first by combining ring-opening polymerization (ROP), atom transfer radical polymerization (ATRP), and post- modification techniques, where OEGMA and FA are oligo(ethylene glycol) monomethyl ether methacrylate and folic acid-bearing moieties, respectively. A model hydrophobic anticancer drug, paclitaxel (PTX), and 4 nm SPIO nanoparticles were then loaded into micellar cores and hydrophilic coronas, respectively, of mixed micelles fabricated from PCL-b-PGMA and PCL-b-P(OEGMA-co-FA) diblock copolymers by taking advantage of the hydrophobicity of micellar cores and strong affinity between 1,2-diol moieties in PGMA and Fe atoms at the surface of SPIO nanoparticles. The controlled and sustained release of PTX from hybrid micelles was achieved, exhibiting a cumulative release of ~61% encapsulated drugs (loading content, 8.5 w/w%) over ~130 h. Compared to that of surfactant-stabilized single SPIO nanoparticles (r(2) = 28.3 s(-1) mM(-1) Fe), the clustering of SPIO nanoparticles within micellar coronas led to considerably enhanced T(2) relaxivity (r(2) = 121.1 s(-1) mM(-1) Fe), suggesting that hybrid micelles can serve as a T(2)-weighted MR imaging contrast enhancer with improved performance. Moreover, preliminary experiments of in vivo MR imaging were also conducted. These results indicate that amphiphilic block copolymer micelles surface embedded with SPIO nanoparticles at the hydrophilic corona can act as a new generation of nanoplatform integrating targeted drug delivery, controlled release, and disease diagnostic functions.