gebhart/patrepeval huggingface dataset:
Interplay of alloying and ordering on the electronic structure ofGaxIn1−xPalloys (2008)

In this work, we extend the study of the electronic structure of disordered and ordered ${\text{Ga}}_{x}{\text{In}}_{1\ensuremath{-}x}\text{P}$ alloys from the focus of most previous effort, $x\ensuremath{\sim}0.5$, to the whole composition range, $0&lt;x&lt;1$, using an improved empirical pseudopotential method with a supercell approach that employs a sufficiently large supercell size of $\ensuremath{\sim}28\text{ }000$ atoms---a size needed to realistically model disordered and partially ordered alloys. This study provides insights into the underlying physics of the alloy system in two important phases---disordered and CuPt ordered---and the interplay of alloying and ordering effects. It also offers much-needed guidance for the optimal use of ordering phenomenon in a range of applications including telecommunications, photovoltaics, and solid-state lighting. Critical-point energies, interband transition matrix elements, and optical anisotropy are calculated for both the disordered and ordered phases. The deviation of the wave function of an alloy state from that of a virtual-crystal state is analyzed using a spectral function. The implications of such deviation are examined explicitly for the above-mentioned properties. Unusual ordering effects are revealed in the indirect-band-gap composition region of the alloy. The connection and distinction between the ordered and disordered structures are discussed. An often-used perturbation theory, known as ``a quasicubic model,'' is found to be reasonably accurate for predicting the anisotropy of the interband transition but inadequate for predicting the intensity variation with varying order parameter.
ChemInform Abstract: Hybrid Anthracyclines from a Genetically Engineered Streptomyces galilaeus Mutant. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Prevalence of retinal vein occlusion in the Australian National Eye Health Survey (2017)

These data suggest that retinal vein occlusion is relatively uncommon in the non-Indigenous Australians aged 50 years and over and Indigenous Australians aged 40 years and over. Similar to previous Australian and international reports, the prevalence of retinal vein occlusion rose sharply with age.
Fenofibrate in cancer: mechanisms involved in anticancer activity (2015)

<ns4:p> <ns4:bold>Objective:</ns4:bold> To review the mechanisms of anti-cancer activity of fenofibrate (FF) and other Peroxisome Proliferator Activator Receptor α (PPARα) agonists based on evidences reported in the published literature. </ns4:p> <ns4:p> <ns4:bold>Methods:</ns4:bold> We extensively reviewed the literature concerning FF as an off target anti-cancer drug. Controversies regarding conflicting findings were also addressed. </ns4:p> <ns4:p> <ns4:bold>Results:</ns4:bold> The main mechanism involved in anti-cancer activity is anti-angiogenesis through down-regulation of Vascular Endothelial Growth Factor (VEGF), Vascular Endothelial Growth Factor Receptor (VEGFR) and Hypoxia Inducible factor-1 α (HIF-1α), inhibition of endothelial cell migration, up-regulation of endostatin and thrombospondin-1, but there are many other contributing mechanisms like apoptosis and cell cycle arrest, down-regulation of Nuclear Factor Kappa B (NF-kB) and Protein kinase B (Akt) and decrease of cellular energy by impairing mitochondrial function. Growth impairment is related to down-regulation of Phospho-Inositol 3 Kinase (PI3K)/Akt axis and down-regulation of the p38 map kinase (MAPK) cascade. A possible role should be assigned to FF stimulated over-expression of Tribbles Homolog-3 (TRIB3) which inhibits Akt phosphorylation. Important anti-cancer and anti-metastatic activities are due to down-regulation of MCP-1 (monocyte chemotactic protein-1), decreased Metalloprotease-9 (MMP-9) production, weak down-regulation of adhesion molecules like E selectin, intercellular adhesion molecules (ICAM) and Vascular Endothelial Adhesion Molecules (VCAM), and decreased secretion of chemokines like Interleukin-6 (IL-6), and down-regulation of cyclin D-1. There is no direct link between FF activity in lipid metabolism and anticancer activity, except for the fact that many anticancer actions are dependent from PPARα agonism. FF exhibits also PPARα independent anti-cancer activities. </ns4:p> <ns4:p> <ns4:bold>Conclusions:</ns4:bold> There are strong evidences indicating that FF can disrupt growth-related activities in many different cancers, due to anti-angiogenesis and anti-inflammatory effects. Therefore FF may be useful as a complementary adjunct treatment of cancer, particularly included in anti-angiogenic protocols like those currently increasingly used in glioblastoma. There are sound reasons to initiate well planned phase II clinical trials for FF as a complementary adjunct treatment of cancer. </ns4:p>
Photochemistry of ruthenium complexes. Ligand isomerization via orbitally different excited states (1971)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhotochemistry of ruthenium complexes. Ligand isomerization via orbitally different excited statesDavid G. Whitten and Phoebe P. ZarnegarCite this: J. Am. Chem. Soc. 1971, 93, 15, 3776–3777Publication Date (Print):July 1, 1971Publication History Published online1 May 2002Published inissue 1 July 1971https://doi.org/10.1021/ja00744a042RIGHTS & PERMISSIONSArticle Views224Altmetric-Citations46LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (288 KB) Get e-Alerts Get e-Alerts
Channel Norm-Based User Scheduler in Coordinated Multi-Point Systems (2009)

In this paper, we address the problem of user scheduling in downlink coordinated multi-point transmission (CoMP) systems, where multiple users are selected and then served with zero forcing beamformer simultaneously by several cooperative base stations (BSs). To reduce the enormous overhead led by obtaining full channel state information at the transmitter, a low-feedback user scheduling method called channel norm-based user scheduler (NUS), is proposed by exploiting the asymmetric channel feature of CoMP systems. Simulation results show that the channel norm provides sufficient information for user scheduling when each BS has one antenna, where the performance gap between the NUS and the greedy user selection (GUS) is negligible with respect to both the cell average throughput and the cell edge throughput. When each BS has multiple antennas, NUS is inferior to GUS, but still significantly outperforms the uncoordinated systems.
Development and Validation of a Polygenic Risk Score for Stroke in the Chinese Population (2021)

This study provides Class I evidence that metaPRS is predictive of stroke risk.
Contention-aware admission control for ad hoc networks (2005)

An admission control algorithm must coordinate between flows to provide guarantees about how the medium is shared. In wired networks, nodes can monitor the medium to see how much bandwidth is being used. However, in ad hoc networks, communication from one node may consume the bandwidth of neighboring nodes. Therefore, the bandwidth consumption of flows and the available resources to a node are not local concepts, but related to the neighboring nodes in carrier-sensing range. Current solutions do not address how to perform admission control in such an environment so that the admitted flows in the network do not exceed network capacity. In this paper, we present a scalable and efficient admission control framework - contention-aware admission control protocol (CACP) - to support QoS in ad hoc networks. We present several options for the design of CACP and compare the performance of these options using both mathematical analysis and simulation results. We also demonstrate the effectiveness of CACP compared to existing approaches through extensive simulations.
Control of Vascular Permeability and Vascular Smooth Muscle in the Respiratory Tract by Multiple Neuropeptides (1988)

Recent evidence suggests that a population of primary afferent neurons which terminate in the upper and lower airways contains several coexisting peptides. Thus, substance P was found to coexist with at least three structurally related tachykinins, viz. neurokinin A, neuropeptide K and an eledoisin-like peptide. Furthermore, calcitonin gene-related peptide which is structurally not related to tachykinins is also present in the same neurons which innervate a variety of peripheral tissues. Substance P, neurokinin A, eledoisin-like peptide and calcitonin gene-related peptide can simultaneously be released from central and peripheral branches of primary sensory neurons, whereas a release of neuropeptide K could not be demonstrated. Local inflammatory mediators like bradykinin or histamine also released multiple peptides in the airways and caused vascular protein leakage which is partly dependent on intact sensory nerves. In experimental animals, tachykinins as well as calcitonin gene-related peptide caused vasodilatation, whereas tachykinins but not calcitonin gene-related peptide caused an increase in vascular protein leakage. In humans, intranasally administered substance P (but not calcitonin gene-related peptide) lead to nasal obstruction as measured by rhinomanometry, and to secretion. It is suggested that activation of peripheral endings of perivascular primary sensory neurons causes vasodilatation and increase in vascular protein leakage by simultaneous action of several neuropeptides including tachykinins and calcitonin gene-related peptide.
Determination of theω→π+π−Decay Amplitude from Photoproduction (1971)

Interference between ${\ensuremath{\rho}}^{0}$ and $\ensuremath{\omega}$ photoproduced from carbon, aluminum, and lead has been studied in the $2\ensuremath{\pi}$ decay mode. The branching ratio $\frac{(\ensuremath{\omega}\ensuremath{\rightarrow}2\ensuremath{\pi})}{(\ensuremath{\omega}\ensuremath{\rightarrow}3\ensuremath{\pi})}$ is 2.8 \ifmmode\pm\else\textpm\fi{} 0.6%. The phase difference between the decay amplitudes $\ensuremath{\omega}\ensuremath{\rightarrow}2\ensuremath{\pi}$ and ${\ensuremath{\rho}}^{0}\ensuremath{\rightarrow}2\ensuremath{\pi}$ is 63\ifmmode^\circ\else\textdegree\fi{} \ifmmode\pm\else\textpm\fi{} 16\ifmmode^\circ\else\textdegree\fi{}.
Incorporation and distribution of benzoquinone into liposomes containing amphilic zinc(II) porphyrin as studied by the quenching of the excited state (1991)

The amphiphilic porphinato zinc(II), i.e.[5, 10, 15,20-tetra{α,α,α,α,-o-[2′,2′-dimethyl-20′-((2″-trimethyl-ammonio) ethyl) phosphonatoxy octaneamido]phenyl}porphinato]zinc(II) complex (abbreviated to ZnP), was embedded in the liposomes of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC). The electron-transfer reaction from the excited state of the liposome-embedded ZnP to benzoquinone (BQ) added to the outer aqueous phase has been studied. Electron transfer occurred from both the triplet and the singlet excited states. The study of the singlet lifetime shows that the fluorescence is quenched statically, indicating the incorporation of BQ into the liposomes. Stepwise incorporation of BQ into the quenching sphere around ZnP was proposed to explain the quenching behaviour and, by calculation, the equilibrium constant of the incorporation was correlated with the relative emission yield. The equilibrium constant for the incorporation of BQ into the quenching sphere around ZnP was obtained from the quenching experiments and the distribution of BQ in the quenching sphere is presented.
Design of radial basis function network as classifier in face recognition using eigenfaces (2002)

In this paper we investigate alternative designs of a radial basis function network acting as classifier in a face recognition system. The inputs to the RBF network are the projections of a face image over the principal components. A database of 250 facial images of 25 persons is used for training and evaluation. Two RBF designs are studied: the forward selection and the Gaussian mixture model. Both designs are also compared to the conventional Euclidean and Mahalanobis classifiers. A set of experiments evaluates the recognition rate of each method as a function of the number of principal components used to characterize the image samples. The results of the experiments indicate that the Gaussian mixture model RBF achieves the best performance while allowing less neurons in the hidden layer. The Gaussian mixture model approach shows also to be less sensitive to the choice of the training set.
Temozolomide in the treatment of children with newly diagnosed diffuse intrinsic pontine gliomas: a report from the Children's Oncology Group (2011)

An open-label phase II study (ACNS0126) testing the efficacy of chemoradiotherapy with temozolomide (TMZ) followed by adjuvant TMZ was conducted by the Children's Oncology Group. During the period from July 6, 2004 through September 6, 2005, 63 children with newly diagnosed diffuse intrinsic pontine glioma (DIPG) were enrolled in the study. All patients received TMZ at a dosage of 90 mg/m(2)/day for 42 days to a dose of 59.4 Gy. Four weeks following irradiation, TMZ was given at a dosage of 200 mg/m(2)/day for 5 days every 28 days, for a total of 10 cycles. The primary objective of the statistical analysis was to determine whether the current treatment produced a 1-year event-free survival (EFS) rate higher than the historical baseline of 21.9% observed in CCG-9941. The mean 1-year EFS (± standard deviation) was 14% ± 4.5%, compared with 21.9% ± 5% for CCG-9941. The P value of the test of comparison of 1-year EFS, based on a 1-sided, 1-sample test of proportions, was .96. There was no evidence that temozolomide produced a 1-year EFS rate higher than 21.9%. The mean 1-year OS (± standard deviation) was 40% ± 6.5%, compared with 32% ± 6% for CCG-9941. The median time to death was 9.6 months. Chemoradiotherapy with TMZ followed by adjuvant TMZ is not more effective than previously reported regimens for the treatment of children with DIPG.
Design and characterization of an all-cryogenic low phase-noise sapphire K-band oscillator for satellite communication (2003)

An all-cryogenic oscillator consisting of a frequency-tunable sapphire resonator, a high-temperature superconducting filter and a pseudomorphic high electron-mobility transistor amplifier was designed for the K-band frequency range. The high quality factor of the resonator above 1 000 000 and the low amplifier phase noise of approximately -133 dBc/Hz at a frequency offset of 1 kHz from the carrier, gave oscillator phase-noise values superior to quartz-stabilized oscillators at the same carrier frequency for offset frequencies higher than 100 Hz. In addition to low phase noise, the oscillator possesses mechanical and electrical frequency tunability. We have implemented a two-step electrical tuning arrangement consisting of a varactor phase shifter integrated within the amplifier circuit (fine tuning by 5 kHz) and a dielectric plunger moved by a piezomechanical transducer inside the resonator housing (coarse tuning by 50 kHz). This tuning range is sufficient for phase locking and for electronic compensation of temperature drifts occurring during operation of the device employing a miniaturized closed-cycle Stirling-type cryocooler.
Overlapping Linear Quadtrees and Spatio-Temporal Query Processing (2000)

In this paper, indexing in spatio-temporal databases by using the technique of overlapping is investigated. Overlapping has been previously applied in various access methods to combine consecutive structure instances into a single structure, without storing identical sub-structures. In this way, space is saved without sacrificing time performance. A new access method, overlapping linear quadtrees is introduced. This structure is able to store consecutive historical raster images, a database of evolving images. Moreover, it can be used to support query processing in such a database. Five such spatio-temporal queries along with the respective algorithms that take advantage of the properties of the new structure are introduced. The new access method was implemented and extensive experimental studies for space efficiency and query processing performance were conducted. A number of results of these experiments are presented. As far as space is concerned, these results indicate that, in the case of similar consecutive images, considerable storage is saved in comparison to independent linear quadtrees. In the case of query processing, the results indicate that the proposed algorithmic approaches outperform the respective straightforward algorithms, in most cases. The region data sets used in experiments were real images of meteorological satellite views and synthetic random images with specified aggregation.
Antibodies to immunoglobulin heavy chain variable regions protect helper cells from specific suicide by radiolabeled antigen (1980)

The antigen-binding receptor of helper T cells was studied by radioactive antigen-caused suicide in vitro. Purified antibodies to immunoglobulin variable regions, obtained from sera of rabbits immunized with isolated VH and VL fragments of mouse myeloma proteins (MOPC 315, XRPC 25), were used to inhibit the binding of radiotoxic antigen. Anti-VH, but not anti-V lambda or anti-V chi inhibited suicide of carrier-primed cells.
3D Vehicle Trajectory Extraction Using DCNN in an Overlapping Multi-Camera Crossroad Scene (2021)

The 3D vehicle trajectory in complex traffic conditions such as crossroads and heavy traffic is practically very useful in autonomous driving. In order to accurately extract the 3D vehicle trajectory from a perspective camera in a crossroad where the vehicle has an angular range of 360 degrees, problems such as the narrow visual angle in single-camera scene, vehicle occlusion under conditions of low camera perspective, and lack of vehicle physical information must be solved. In this paper, we propose a method for estimating the 3D bounding boxes of vehicles and extracting trajectories using a deep convolutional neural network (DCNN) in an overlapping multi-camera crossroad scene. First, traffic data were collected using overlapping multi-cameras to obtain a wide range of trajectories around the crossroad. Then, 3D bounding boxes of vehicles were estimated and tracked in each single-camera scene through DCNN models (YOLOv4, multi-branch CNN) combined with camera calibration. Using the abovementioned information, the 3D vehicle trajectory could be extracted on the ground plane of the crossroad by calculating results obtained from the overlapping multi-camera with a homography matrix. Finally, in experiments, the errors of extracted trajectories were corrected through a simple linear interpolation and regression, and the accuracy of the proposed method was verified by calculating the difference with ground-truth data. Compared with other previously reported methods, our approach is shown to be more accurate and more practical.
Computer-Aided Design and Optimization of a Redundant Robotic System for Automated Fiber Placement Process (2017)

This paper proposes a comprehensive methodology for the computer-aided design and optimization of a robotic workcell for the automated fiber placement. The robotic cell, comprising of a 6-axis industrial manipulator and an actuated positioner, is kinematically redundant with respect to the considered task. An efficient optimization technique for managing these kinematic redundancies is proposed. The robot/positioner motion planning and robotic cell layout design in a CAD environment are presented. To confirm validity of the developed methodology, experimental results are presented that deal with automation of thermoplastic fiber placement process.
Comparison of Hydrogels for the Development of Well-Defined 3D Cancer Models of Breast Cancer and Melanoma (2020)

Bioprinting offers the opportunity to fabricate precise 3D tumor models to study tumor pathophysiology and progression. However, the choice of the bioink used is important. In this study, cell behavior was studied in three mechanically and biologically different hydrogels (alginate, alginate dialdehyde crosslinked with gelatin (ADA-GEL), and thiol-modified hyaluronan (HA-SH crosslinked with PEGDA)) with cells from breast cancer (MDA-MB-231 and MCF-7) and melanoma (Mel Im and MV3), by analyzing survival, growth, and the amount of metabolically active, living cells via WST-8 labeling. Material characteristics were analyzed by dynamic mechanical analysis. Cell lines revealed significantly increased cell numbers in low-percentage alginate and HA-SH from day 1 to 14, while only Mel Im also revealed an increase in ADA-GEL. MCF-7 showed a preference for 1% alginate. Melanoma cells tended to proliferate better in ADA-GEL and HA-SH than mammary carcinoma cells. In 1% alginate, breast cancer cells showed equally good proliferation compared to melanoma cell lines. A smaller area was colonized in high-percentage alginate-based hydrogels. Moreover, 3% alginate was the stiffest material, and 2.5% ADA-GEL was the softest material. The other hydrogels were in the same range in between. Therefore, cellular responses were not only stiffness-dependent. With 1% alginate and HA-SH, we identified matrices that enable proliferation of all tested tumor cell lines while maintaining expected tumor heterogeneity. By adapting hydrogels, differences could be accentuated. This opens up the possibility of understanding and analyzing tumor heterogeneity by biofabrication.
Utility of the Wavelet Transform for LAI Estimation Using Hyperspectral Data (2013)

We employed the discrete wavelet transform to refl ectance spectra obtained from hyperspectral data to improve estimation of LAI in temperate forests. We estimated LAI for 32 plots across a range of forest types in Wisconsin using hemispherical photography. Plot spectra were extracted from AVIRIS data and transformed into wavelet features using the Haar wavelet. Separately, subsets of spectral bands and the Haar features selected by a genetic algorithm were used as independent variables in linear regressions. Models using wavelet coeffi cients explained the most variance for both broadleaf plots (R 2 = 0.90 for wavelet features versus R 2 = 0.80 for spectral bands) and all plots independent of forest type (R 2 = 0.79 for wavelet features vs. R 2 = 0.58 for spectral bands). The forest-type specifi c models were better than the models using all plots combined. Overall, wavelet features appear superior to band refl ectances alone for estimating temperate forest LAI using hyperspectral data.