gebhart/patrepeval huggingface dataset:
Unsupervised categorisation approaches for technical support automated agents (2007)

In this paper we describe an unsupervised approach for the automated categorisation of utterances into predefined categ ories of symptoms (or problems) within the framework of a technical support automated agent. The utterance classification is pe rformed based on an iterative K-means clustering method. In order to improve the lower accuracy typical of unsupervised algorithms, we have analysed two different enhancements of the classification algorithm. The first method exploits the affin ity among words by automatically extracting classes of semantically equivalent terms. The second approach consists of a disambiguation technique based on a new criterion to estimate the relevance of terms for the classification. An analysis of the results of an experimental evaluation performed on a corpus of 34848 utterances concludes the paper. Index Terms: automated agents, automated categorisation, unsupervised learning, related words, term relevance.
Ultrafast electronic dynamics in laser-excited crystalline bismuth (2013)

Femtosecond spectroscopy is applied to study transient electronic processes in bismuth. The components with relaxation times of 1 ps, 7 ps, and ∼1 ns are detected in the photoinduced reflectivity response of the crystal. To facilitate assignment of the observed relaxation to the decay of particular excited electronic states, we use pump pulses with central wavelengths ranging from 400 to 2300 nm. Additionally, we examine the variation of parameters of coherent A1g phonons upon the change of excitation and probing conditions. Data analysis reveals significant wavevector dependence of electron-hole and electron-phonon coupling strength along Γ-T direction of the Brillouin zone.
Video query processing in the VDBMS testbed for video database research (2003)

The increased use of video data sets for multimedia-based applications has created a demand for strong video database support, including efficient methods for handling the content-based query and retrieval of video data. Video query processing presents significant research challenges, mainly associated with the size, complexity and unstructured nature of video data. A video query processor must support video operations for search by content and streaming, new query types, and the incorporation of video methods and operators in generating, optimizing and executing query plans. In this paper, we address these query processing issues in two contexts, first as applied to the video data type and then as applied to the stream data type. We first present the query processing functionality of the VDBMS video database management system as a framework designed to support the full range of functionality for video as an abstract data type. We describe two query operators for the video data type which implement the rank-join and stop-after algorithms. As videos may be considered streams of consecutive image frames, video query processing can be expressed as continuous queries over video data streams. The stream data type was therefore introduced into the VDBMS system, and system functionality was extended to support general data streams. From this viewpoint, we present an approach for defining and processing streams, including video, through the query execution engine. We describe the implementation of several algorithms for video query processing expressed as continuous queries over video streams, such as fast forward, region-based blurring and left outer join. We include a description of the window-join algorithm as a core operator for continuous query systems, and discuss shared execution as an optimization approach for stream query processing.
MITOSIS AND CYTOKINESIS IN THE PRASINOPHYCEAE. I. MANTONIELLA SQUAMATA (MANTON AND PARKE) DESIKACHARY (1981)

Mitosis in Mantoniella squamata (Manton and Parke) Desikachary, a small scale‐covered green monad, is presented. Organelle replication precedes nuclear division and begins with the replication of the chloroplast. As the chloroplasts separate, the Golgi and flagellar apparatuses divide. The discoid microbody enlarges and becomes ‘V'‐shaped, with the arms extending toward depressions in the pyrenoid stalks of the chloroplasts. At prophase, microtubules produced by an amorphous microtubule organizing center enter the nucleus via polar fenestre. The nuclear membrane remains intact. As the chloroplasts migrate further apart, the spindle pole‐to‐pole distance increases. By metaphase, daughter‐cell lobes are discernible as a cleavage furrow, which appears as early as prophase, and begins to incise the cell. A single Golgi apparatus is situated near the spindle pole; the flagellar apparatus lies adjacent to the pole. The cleavage furrow continues to constrict the cell, resulting in a narrowing isthmus containing the elongate microbody, nucleus and a rootlet system connecting the basal bodies of the daughter flagella. At telophase, no extra‐nuclear microtubular systems other than the previously observed rootlet are present and the nuclei remain separated from each other. In cells undergoing multiple divisions to produce more than two daughter cells, the orientation of organelles changes somewhat, with the basal bodies and the Golgi apparatus separating daughter nuclei prior to the onset of cytokinesis. The mechanics of mitosis in Mantoniella are compared with other green monads and the evolutionary implications discussed.
USOC Coaching Education Department/Sport Performance Division: “What We Do” (2010)

We would
86Y-Labeled Albumin-Binding Fibroblast Activation Protein Inhibitor for Late-Time-Point Cancer Diagnosis (2022)

Fibroblast activation protein inhibitor (FAPI) is a novel quinoline-based radiopharmaceutical that has theranostic potential, yet the limited tumor retention hinders late-time diagnosis and radionuclide treatment. This study synthesized four albumin-binding FAPIs (TE-FAPI-01 to 04) and evaluated their in vitro stability, binding affinity, in vivo biodistribution, and tumor uptake with <sup>68</sup>Ga, <sup>86</sup>Y, and <sup>177</sup>Lu labeling, aiming to select the best molecule that has favorable pharmacokinetics to extend the blood circulation and tumor uptake in FAP-expressing tumors. All TE-FAPIs were stable in saline and plasma and displayed high FAP-binding affinity, with IC<sub>50</sub> values ranging from 3.96 to 34.9 nmol/L. The capabilities of TE-FAPIs to be retained in circulation were higher than that of FAPI-04, and TE-FAPI-04 displayed minimum physiological uptake in major organs compared with other molecules. TE-FAPI-03 and TE-FAPI-04 exhibited persistent tumor accumulation, with tumor radioactivity 24 h after administration of 2.84 ± 1.19%ID/g and 3.86 ± 1.15%ID/g for <sup>177</sup>Lu-TE-FAPI-03 and <sup>177</sup>Lu-TE-FAPI-04, respectively, both of which outperformed <sup>177</sup>Lu-FAPI-04 (0.34 ± 0.07%ID/g). TE-FAPI-04 was recognized as the albumin-binding FAPI with the most favorable pharmacokinetics and imaging performance. The enhanced circulation half-life and tumor uptake of TE-FAPI-04 aided the theranostics of malignant tumors and warrant further clinical investigations.
Development and Validation of an Open-Source Real-Time Freehand 3-Dimensional Ultrasound Navigation System for Liver Surgery with GPGPU Acceleration (2009)

To achieve longterm survival after resection of liver tumors, accurate resection margins are essential. Image guided surgery with navigational support has the potential to increase surgical accuracy significantly, thus making the operation more reliable. In this article we describe an image guided navigation system for liver surgery. Our platform uses GPU acceleration to display in real-time reconstructed 3-dimensional freehand ultrasound volumes in combination with tracked surgical instruments. We evaluated the accuracy and the performance of our system on a phantom study. The results of our study demonstrate that our image guided navigation system has the potential to introduce significant improvements in the field of liver surgery.
Sensitivity Analysis in Bayesian Networks: From Single to Multiple Parameters (2012)

Previous work on sensitivity analysis in Bayesian networks has focused on single parameters, where the goal is to understand the sensitivity of queries to single parameter changes, and to identify single parameter changes that would enforce a certain query constraint. In this paper, we expand the work to multiple parameters which may be in the CPT of a single variable, or the CPTs of multiple variables. Not only do we identify the solution space of multiple parameter changes that would be needed to enforce a query constraint, but we also show how to find the optimal solution, that is, the one which disturbs the current probability distribution the least (with respect to a specific measure of disturbance). We characterize the computational complexity of our new techniques and discuss their applications to developing and debugging Bayesian networks, and to the problem of reasoning about the value (reliability) of new information.
CCDC 1842078: Experimental Crystal Structure Determination (2018)

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
Multiple Linkage Disequilibrium Mapping Methods to Validate Additive Quantitative Trait Loci in Korean Native Cattle (Hanwoo) (2015)

The efficiency of genome-wide association analysis (GWAS) depends on power of detection for quantitative trait loci (QTL) and precision for QTL mapping. In this study, three different strategies for GWAS were applied to detect QTL for carcass quality traits in the Korean cattle, Hanwoo; a linkage disequilibrium single locus regression method (LDRM), a combined linkage and linkage disequilibrium analysis (LDLA) and a BayesCπ approach. The phenotypes of 486 steers were collected for weaning weight (WWT), yearling weight (YWT), carcass weight (CWT), backfat thickness (BFT), longissimus dorsi muscle area, and marbling score (Marb). Also the genotype data for the steers and their sires were scored with the Illumina bovine 50K single nucleotide polymorphism (SNP) chips. For the two former GWAS methods, threshold values were set at false discovery rate <0.01 on a chromosome-wide level, while a cut-off threshold value was set in the latter model, such that the top five windows, each of which comprised 10 adjacent SNPs, were chosen with significant variation for the phenotype. Four major additive QTL from these three methods had high concordance found in 64.1 to 64.9Mb for Bos taurus autosome (BTA) 7 for WWT, 24.3 to 25.4Mb for BTA14 for CWT, 0.5 to 1.5Mb for BTA6 for BFT and 26.3 to 33.4Mb for BTA29 for BFT. Several candidate genes (i.e. glutamate receptor, ionotropic, ampa 1 [GRIA1], family with sequence similarity 110, member B [FAM110B], and thymocyte selection-associated high mobility group box [TOX]) may be identified close to these QTL. Our result suggests that the use of different linkage disequilibrium mapping approaches can provide more reliable chromosome regions to further pinpoint DNA makers or causative genes in these regions.
Snake bite in Nigeria. (2001)

Four families of venomous snakes are found in Nigeria--Viperidae, Elapidae, Colubridae and Actraspididae but three species carpet viper (Echis ocellatus), black-necked spitting cobra (Naja nigricollis) and puff adder (Bitis arietans), belonging to the first two families, are the most important snakes associated with envenoming in Nigeria. The incidence of bites has been reported as 497 per 100,000 population per year with a 12 percent natural mortality, with Echis ocellatus accounting for at least 66 percent in certain foci. Bites occur more often while victims were farming, herding or walking although the spitting cobra may bite victims who roll upon it in their sleep. Carpet viper venom contains a prothrombin activating procoagulant, haemorrhagin and cytolytic fractions which cause haemorrhage, incoagulable blood, shock and local reactions/ necrosis. The spitting cobra bite manifests with local tissue reaction and occassionally with bleeding from the site of bite, but no classic neurotoxic feature has been observed except following Egyptian cobra (N. haje) bites. Cardiotoxicity and renal failure may occassionally occur following bites by the carpet viper and the puff adder. In the laboratory, haematological and other features are noted and immunodiagnosis has a role in species identification. Immobilisation of the bitten limb is probably the single most important first aid measure. Antivenom should be used cautiously when indicated. As only 8.5 percent of snake bite victims attend hospitals in Nigeria, health education should be the main preventive measure, mean-while, the study of immunisation of occupationally predisposed individuals in endemic areas should be intensified. A new Fab fragment antivenom specific to Nigerian Echis ocellatus was investigated clinically, just as the local herbs-Aristolochia spp, Guiera spp and Schummaniophyton spp are investigated experimentally.
A cytotoxic peptide from a marine sponge exhibits ion channel activity through vectorial‐insertion into the membrane (2010)

A cytotoxic peptide, polytheonamide B (pTB), from marine sponge was examined for cytotoxic spectrum and specific activity to mammalian cells was demonstrated. pTB is composed of alternative D- and L-amino acid residues throughout the 48-mer peptide. This suggests the formation of a β-helix similar to gramicidin channels. Planar bilayer experiments revealed that pTB forms monovalent cation-selective channels, being compatible with the inner pore diameter of ∼4Å for a β-helical structure. pTB penetrated vectorially into the membrane, formed a channel by means of a single molecule, and remained in the membrane. These functional properties may account for specific cytotoxic activity.
Organization and function of transmitter release sites at the neuromuscular junction (2013)

The neuromuscular junction is known as a strong and reliable synapse. It is strong because it releases an excess of chemical transmitter, beyond what is required to bring the postsynaptic muscle cell to threshold. Because the synapse can sustain suprathreshold muscle activation during short trains of action potentials, it is also reliable. The presynaptic mechanisms that lead to reliability during short trains of activity have only recently been elucidated. It appears that there are relatively few calcium channels in individual active zones, that channels open with a low probability during action potential stimulation and that even if channels open the resulting calcium flux only rarely triggers vesicle fusion. Thus, each synaptic vesicle may only associate with a small number of calcium channels, forming an unreliable single vesicle release site. Strength and reliability of the neuromuscular junction emerge as a result of its assembly from thousands of these unreliable single vesicle release sites. Hence, these synapses are strong while at the same time only releasing a small subset of available docked vesicles during each action potential, thus conserving transmitter release resources. This prevents significant depression during short trains of action potential activity and confers reliability.
Cross sections for the Ar-L X-ray emission in collisions of He+, Ne+and Ar+ions with Ar atoms (1974)

Ar-L X-ray production cross sections for collisions of He+, Ne+ and Ar+ ions of energies between 100 keV and 1 MeV with Ar atoms have been measured. The results are in good agreement with comparable cross section data.
Chemical Reactions and Processes under Flow Conditions (2009)

Pharmaceutical and fine chemical products are typically synthesised batchwise which is an anomaly since batch processes have a series of practical and economical disadvantages. On the contrary, flow continuous processes present a series of advantages leading to new ways to synthesise chemical products. Flow processes - * enable control reaction parameters more precisely (temperature, residence time, amount of reagents and solvent etc.), leading to better reproducibility, safer and more reliable processes * can be performed more advantageously using immobilized reagents or catalysts * improve the selectivity and productivity of the process and possibly even the stability of the catalyst * offer opportunities for heat exchange and energy conservation as well as an easy separation and recycling of the reactants and products by adequate process design * achieve multistep syntheses by assembling a line of reactors with minimum or no purification in between two reaction steps * can be assured by facile automation * scale-up can be easily conducted by number-up With all the new research activity in manufacturing chemical products, this comprehensive book is very timely, as it summarises the latest trends in organic synthesis. It gives an insight into flow continuous processes, outlining the basic concepts and explaining the terminology of, and systems approach to, process design dealing with both homogeneous and heterogeneous catalysis and mini- or micro-reactors. The book contains case studies, extensive bibliographies and reference lists in each chapter to enable the reader to grasp the contents and to go on to more detailed texts on specific subjects if desired. The book is written by both organic chemists and engineers giving a multidisciplinary vision of the new tools and methodologies in this field. It is essential reading for organic chemists (in industry or academia) working alongside chemical engineers or who want to undertake chemical engineering projects. It will also be of interest for chemical engineers to see how basic engineering concepts are applied in modern organic chemistry.
A Survey of Soft Tissue Tumor-Like Lesions of Oral Cavity: A Clinicopathological Study (2008)

Background and Objective: Different mechanisms may lead to the development of soft tissue tumor-like lesions in the oral cavity. Many of these lesions can be identified as specific entities on the basis of their histopathological features and are divided into fibrous, vascular, and giant cell types. The purpose of this study was to establish the relative prevalence of the different histopathological aspects of biopsies of oral soft tissue tumor-like lesions at School of Dentistry, Kerman Univ. Med. Sci. Materials and Methods: Documents and records of 260 patients with localized lesions of oral tissues diagnosed from March 1996 to March 2004 were reviewed. The lesions were classified into either fibrous or soft hemorrhagic lesions. Clinical data regarding age, gender, location, and treatment of lesions were obtained for each case. Data included in the present retrospective study were analyzed by SPSS statistical software (13.5) using t- test and chi-square tests. Results: A total of 260 surgical specimens of lesions of the oral cavity presented clinically were studied; 143 cases (55%) had fibrous lesions and 117 cases (45%) had soft hemorrhagic lesions. The fibrous lesions included 91 cases (63.6%) of gingival lesions, whereas 98 cases (83.76%) of the soft hemorrhagic lesions had gingival lesions. The patients were simultaneously treated by excisional biopsy and elimination of the chronic irritant. Conclusion: Oral lesions are often detected by dental professionals, surgeons and ENT specialists. Knowledge of the frequency and presentation of the most common oral lesions is beneficial in developing a clinical impression of such lesions encountered in practice.
Evolution of the Taste of a Bitter Camembert Cheese during Ripening: Characterization of a Matrix Effect (2001)

The objective of this study was to characterize the effect of ripening on the taste of a typically bitter Camembert cheese. The first step was to select a typically bitter cheese among several products obtained by different processes supposed to enhance this taste defect. Second, the evolution of cheese taste during ripening was characterized from a sensory point of view. Finally, the relative impact of fat, proteins, and water-soluble molecules on cheese taste was determined by using omission tests performed on a reconstituted cheese. These omission tests showed that cheese taste resulted mainly from the gustatory properties of water-soluble molecules but was modulated by a matrix effect due to fat, proteins, and cheese structure. The evolution of this matrix effect during ripening was discussed for each taste characteristic.
A measurement distribution framework for cooperative navigation using multiple AUVs (2010)

In recent years underwater survey and surveillance missions with more than a single Autonomous Underwater Vehicle (AUV) have become more common thanks to more reliable and cheaper platforms, as well as the addition of remote command and control communications using, for example, the WHOI acoustic modem. However cooperative navigation of AUVs has thus far been limited to a single AUV supported by a dedicated surface vehicle with access to GPS. In this paper a scalable and modular framework is presented in which any number of vehicles can broadcast, forward and acknowledge range, dead-reckoning, feature and GPS measurements so that the full fleet of AUVs can navigate and cooperate in a consistent and accurate manner. The approach is independent of the resultant application-such as recursive state estimation or full pose optimization. Trade-offs between the number of vehicles, the condition of the communication channel and rate at which updates are available are also discussed. Finally performance is illustrated in a realistic experiment.
High-Density Linkage Map Construction and Mapping of Salt-Tolerant QTLs at Seedling Stage in Upland Cotton Using Genotyping by Sequencing (GBS) (2017)

Over 6% of agricultural land is affected by salinity. It is becoming obligatory to use saline soils, so growing salt-tolerant plants is a priority. To gain an understanding of the genetic basis of upland cotton tolerance to salinity at seedling stage, an intra-specific cross was developed from CCRI35, tolerant to salinity, as female with Nan Dan (NH), sensitive to salinity, as the male. A genetic map of 5178 SNP markers was developed from 277 F<sub>2:3</sub> populations. The map spanned 4768.098 cM, with an average distance of 0.92 cM. A total of 66 QTLs for 10 traits related to salinity were detected in three environments (0, 110, and 150 mM salt treatment). Only 14 QTLs were consistent, accounting for 2.72% to 9.87% of phenotypic variation. Parental contributions were found to be in the ratio of 3:1, 10 QTLs from the sensitive and four QTLs from the resistant parent. Five QTLs were located in A<sub>t</sub> and nine QTLs in the D<sub>t</sub> sub-genome. Moreover, eight clusters were identified, in which 12 putative key genes were found to be related to salinity. The GBS-SNPs-based genetic map developed is the first high-density genetic map that has the potential to provide deeper insights into upland cotton salinity tolerance. The 12 key genes found in this study could be used for QTL fine mapping and cloning for further studies.