gebhart/patrepeval huggingface dataset:
Synthesis of chirally deuteriated phthalimido-propanols and evaluation of their absolute stereochemistry (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of chirally deuteriated phthalimido-propanols and evaluation of their absolute stereochemistryP. C. Prabhakaran, Steven J. Gould, Gary R. Orr, and James K. CowardCite this: J. Am. Chem. Soc. 1988, 110, 17, 5779–5784Publication Date (Print):August 1, 1988Publication History Published online1 May 2002Published inissue 1 August 1988https://pubs.acs.org/doi/10.1021/ja00225a032https://doi.org/10.1021/ja00225a032research-articleACS PublicationsRequest reuse permissionsArticle Views977Altmetric-Citations29LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
First-Principles Mechanistic Study of the Initial Growth of SrO by Atomic Layer Deposition on TiO2-Terminated SrTiO3 (001) (2020)

Perovskite oxides with a high dielectric constant such as SrTiO3 have received much attention as alternative dielectrics for next generation semiconductor devices. The growth of SrTiO3 thin films by atomic layer deposition (ALD) is commonly achieved by alternating deposition cycles of SrO and TiO2. However, the underlying reaction mechanisms remain rather poorly understood despite their importance in optimizing the ALD process for desired film properties. In this work, we investigate the adsorption and reaction of Sr(Cp)2 as a Sr precursor and H2O as an oxidizer on TiO2-terminated SrTiO3 (001) using dispersion-corrected density functional theory calculations. The adsorption energy of Sr(Cp)2 is predicted to be Eads = −2.70 eV at low coverage and its magnitude decreases only by 0.16 eV until the surface is fully saturated at 0.25 monolayer (ML) coverage. The Sr(Cp)2 adsorption on the first adsorption layer is found to be much weaker, yielding Eads = −1.11 eV. The significant difference in Eads can contribute favorably to single-layer SrO growth on the TiO2-terminated surface. In addition, the low saturation coverage of 0.25 ML may suggest that at least four successive cycles of Sr(Cp)2 dose would be required to form a single SrO layer. Our calculations also demonstrate that the kinetics and energetics of Sr(Cp)2 decomposition depend strongly on H2O coverage and the resulting Sr atoms may hardly undergo surface diffusion at typical ALD temperatures (< 300 °C). Our work highlights that a deeper understanding of surface chemistry evolution during the ALD process still needs to be developed to better predict and control the growth behavior and resulting properties of SrTiO3 thin films, warranting further systematic investigation.
Charge transfer at oxygen/zirconia interface at elevated temperatures: Part 6 Work function measurements (2005)

The present paper considers the application of the high temperature Kelvin probe for measurements of changes in work function (WF) of oxide materials during surface reactions at elevated temperatures and in controlled gas phase environments. The method is based on the determination of work function changes from measurements of the contact potential difference (CPD) between the Pt reference electrode and the studied specimen of a metal oxide. Experimental data on work function changes are reported for yttria-stabilised cubic zirconia (10 mol-%Y2O3) during oxidation and reduction experiments at 1173 K. It was found that changes in CPD exhibit good stability with time (2 mV drift over 15 h). The reproducibility of CPD changes during successive oxidation and reduction experiments remains within 0·5 mV. Good agreement was revealed between the obtained experimental data and the theoretical model describing the effect of oxygen partial pressure on the WF of both zirconia and the Pt electrode.
Navy Laser Radar Overview (1983)

The U.S. Navy is pursuing the use of CO 2 laser radar technology for a variety of applications. Rather than attempt to describe the specifics of these applications and rapidly get into classification problems, three major areas which support the uses of the technology will be described. Critical areas include componentry, signatures, and airborne imaging sensors. Under the componentry area a manufacturing technology program for CO 2 waveguide lasers will be described. For the signatures part of this discussion a Navy built and operated van installation (Navy Active Target Signatures (NATS) System) will be described. Finally some results from a flight test conducted on a UH-IN helicopter of an imaging sensor will be reviewed.
Advance concepts in conveyer controls for coal ash-handling systems (1983)

The electromechanical relays and timers used for coal ash-handling conveyer systems were replaced by programmable controllers that reduced the size and complexity of utility control panels as well as improving the on-time startup of new conveyers. Customers requested further improvements in the microcomputer systems that would detect individual valve faults, monitor water consumption, and monitor line and pump wear as reliable remote input-output systems became available for distributed control. Hierarchial control adds high-speed communications. Users can choose between total redundancy and a redundancy supervisor system for back-up. 4 figures. (DCK)
Waveguide Slot Array with Wide Frequency Scanning (2020)

A linear waveguide slot antenna with a frequency scanning sector of 180° is proposed and studied. The antenna represents a rectangular metal waveguide filled with a two-layer dielectric with periodic steps of thickness in one layer and periodic triple transverse slots in the wide wall of the waveguide. A scanning sector of 180° is reached with the aid of two scanning regimes that employ the fundamental (zero) and minus first spatial harmonics. Such a waveguide slot antenna is characterized by a high antenna aperture efficiency in almost entire frequency scanning sector.
XI.—The Pharmacological Action of Harmaline. (1910)

Harmaline is one of two alkaloids found in the seeds of Peganum Harmala , a strong-smelling herbaceous plant belonging to the order of Rutaceæ. This plant grows to a height of from 1 to 3 feet, is much branched, and profusely covered with leaves. It is found wild in S. Europe, Asia Minor, Egypt, Arabia, N.W. India, and Siberia. It is the Πήγανον ἄγριον (wild rue) of Dioscorides, Πήγανον being the name still applied in Greece to several species of Ruta.
Access and Metro Network Convergence for Flexible End-to-End Network Design [Invited] (2017)

This paper reports on the architectural, protocol, physical layer, and integrated testbed demonstrations carried out by the DISCUS FP7 consortium in the area of access&#x2013;metro network convergence. Our architecture modeling results show the vast potential for cost and power savings that node consolidation can bring. The architecture, however, also recognizes the limits of long-reach transmission for low-latency 5G services and proposes ways to address such shortcomings in future projects. The testbed results, which have been conducted end-to-end, across access&#x2013;metro and core, and have targeted all the layers of the network from the application down to the physical layer, show the practical feasibility of the concepts proposed in the project.
Giving Attention to the Unexpected: Using Prosody Innovations in\n Disfluency Detection (2019)

Disfluencies in spontaneous speech are known to be associated with prosodic\ndisruptions. However, most algorithms for disfluency detection use only word\ntranscripts. Integrating prosodic cues has proved difficult because of the many\nsources of variability affecting the acoustic correlates. This paper introduces\na new approach to extracting acoustic-prosodic cues using text-based\ndistributional prediction of acoustic cues to derive vector z-score features\n(innovations). We explore both early and late fusion techniques for integrating\ntext and prosody, showing gains over a high-accuracy text-only model.\n
Features of femtosecond laser pulses interaction with nematic liquid crystals (2005)

We investigate the features of femtosecond laser pulses interaction with pure and dye-doped nematic liquid crystals. For femtosecond laser pulses interacting with dye-doped nematic liquid crystal we found the distinction between the efficiency of liquid crystal director reorientation in comparison to the continuous wave irradiation. The mechanisms responsible for such distinction associated with changes of intermolecular forces under two-photon absorption and light induced changes of anchoring conditions are discussed.
Rhodium‐Catalyzed ortho Acylation of Aromatic Carboxylic Acids (2013)

Neue Richtung: Die Carboxygruppe von Benzoesäuren steuert deren ortho-Acylierung mit Carbonsäureanhydrid in Gegenwart eines Rhodiumkatalysators (siehe Schema; cod=Cyclo-1,5-octadien). Diese ortho-Acylierung bildet eine Ergänzung zu der meta-Selektivität von Friedel-Crafts-Reaktionen. Die Produkte können durch Protodecarboxylierung in Arylketone überführt werden.
Comparison of Cox and Gray’s survival models in severe sepsis* (2004)

We confirm that many of the important predictors of mortality in severe sepsis are nonproportional and find that Gray's model seems best suited for modeling survival in this condition.
Bornova Misketi Şarabının Aroma Maddeleri Üzerine bir Araştırma (1997)

Bu çalışma Bornova misketinden elde edilen bir şarabın aroma maddeleri incelenmiştir. Şaraptaki aroma maddeleri Ambberlit XAD-2 reçinesi ile ekstrakte edilmiş ve analizler gaz kromatografisinde gerçekleştirilmiştir. Aroma maddelerinin tanısında gaz kromatografisi-kütle spektrometresi kullanılmıştır. Yapılan analizleri göre şarapta 3 adet 6 karbonlu bileşik, 17 adet terpenol, 12 adet alkol, 15 adet ester, 1 adet lakton, 4 adet karbonil bileşiği, 4 adet asit, 13 adet fenol, 1 adet azotlu bileşik ve 2 adet 13 karbonlu norizoprenoid olmak üzere toplam 72 adet serbest aroma maddesi ile 3 adet 6 karbonlu bileşik, 21 adet terpenol, 7 adet yüksek alkol, 1 adet karbonil bileşiği, 7 adet fenol ve 3 adet 13 karbonlu norizoprenoid olmak üzere toplam 42 adet bağlı aroma maddesi bulunduğu belirlenmiştir. Öte yandan, misket şarabına tipik aromasını kazandıran, serbest özellikteki terpen bileşikleri miktarı 2216 mg/l olarak saptanmıştır.
M/EEG source reconstruction based on Gabor thresholding in the source space (2011)

International audience
Current issues in the management of paediatric viral hepatitis (2009)

Viral hepatitis poses important problems for children. In preschoolers, hepatitis A virus (HAV) infection frequently causes acute liver failure. Vaccinating toddlers against HAV in countries with high endemicity is expected to decrease mortality. HAV vaccine demonstrates efficacy (comparable to immunoglobulin) as post-exposure prophylaxis. A recently developed vaccine against hepatitis E virus (HEV) may benefit fetal health, because pregnant women are most prone to acute liver failure as a result of HEV. Hepatitis B vaccine continues to demonstrate value and versatility for preventing serious liver disease. With chronic infection, undetectable levels of serum HBV DNA complement e-seroconversion as the preferred outcome measure; suppressed viral load correlates with long-term complications better than HBeAg status. Among Taiwanese children, low pretreatment HBV DNA (<2 x 10(8) copies/ml) strongly predicted response to interferon-alpha. Future paediatric studies must incorporate HBV DNA levels. The rationale for routine treatment of immunotolerant hepatitis B during childhood remains uncertain. Any treatment of chronic hepatitis B in childhood requires consideration of the risks and benefits. Childhood hepatitis C virus (HCV) infection results mainly from mother-to-infant transmission. Babies of HCV-infected women should be tested for serum HCV RNA at 1 month of age. If negative, confirmatory anti-HCV antibody testing may be performed between 12 and 15 months of age. Children with chronic hepatitis C may develop progressive fibrosis/cirrhosis, particularly in the setting of obesity and insulin resistance. Treatment of children chronically infected with genotype 2 or 3 is highly successful: combination therapy of pegylated interferon-alpha and ribavirin is well tolerated and superior to pegylated interferon-alpha alone.
Quadriwave lateral shearing phase imaging of EUV masks (2020)

We present a phase imaging technique for measuring the phase of EUV masks. In this technique we use a Quadriwave Zone Plate (QZP) to superpose four laterally separated copies of the complex amplitude function in the image plane, causing them to interfere onto a detector. By changing the scanning angle, we can control the relative phase between these images, which allows us to extract two orthogonal derivative phases directly, and then subsequently reconstruct the phase of the EUV mask. If the region of interest contains a reference region such as a clear field, the phase can be extracted from the derivative phases directly. Simulations and an experiment are performed to demonstrate the method accuracy.
Weighted least-squares estimation of phase errors for SAR/ISAR autofocus (1999)

A new method of phase error estimation that utilizes the weighted least-squares (WLS) algorithm is presented for synthetic aperture radar (SAR)/inverse SAR (ISAR) autofocus applications. The method does not require that the signal in each range bin be of a certain distribution model, and thus it is robust for many kinds of scene content. The most attractive attribute of the new method is that it can be used to estimate all kinds of phase errors, no matter whether they are of low order, high order, or random. Compared with other methods, the WLS estimation is optimal in the sense that it has the minimum variance of the estimation error. Excellent results have been obtained in autofocusing and imaging experiments on real SAR and ISAR data.
Chirped Laser Dispersion Spectroscopy for Remote Sensing of Methane at 1.65µm – Analysis of System Performance (2013)

A chirped laser dispersion spectroscopy system, operating at 1.65µm to target atmospheric methane, is presented. A discussion of the long-term stability, sensitivity, and long open-path integrated measurements is provided.
Site Conversion of Methoxy Species on ZrO2 (1997)

The site conversion of some bridged (b-) methoxy species to the terminal ones on ZrO2 was directly observed by infrared spectroscopy between 523 and 623 K, accompanied by thermal decomposition of coadsorbed formate species. The observed site conversion was interpreted in terms of methoxy migration on the ZrO2 surface, which was previously supposed to occur in the H/D isotope exchange reaction of both methoxy groups with b-OD groups.
The use of escitalopram beyond major depression: pharmacological aspects, efficacy and tolerability in anxiety disorders (2007)

Escitalopram, the active (S)-enantiomer of citalopram, has been approved in many countries throughout the world for the treatment of depression and anxiety disorders. It is more potent and selective than citalopram in inhibiting serotonin re-uptake in the CNS, and less potent than various other selective serotonin re-uptake inhibitors in relation to other transporter proteins and receptors: in particular, it is six times less potent than citalopram in binding to the histamine H1 and muscarinic receptors. Escitalopram has favourable pharmacokinetics: it is rapidly absorbed, has a bioavailability of 80% and is not affected by food intake. It has little potential for drug interactions: it has low protein binding and, as it is metabolised by three CYP isozymes, any impairment in the activity of one is unlikely to have a significant effect on metabolic clearance. Caution is necessary only when it is coadministered with drugs metabolised by CYP2D6, such as metoprolol, or administered to the elderly or patients with severe hepatic or renal impairment. The multiple-dose pharmacokinetics of oral escitalopram are proportional at a range of doses including its therapeutic doses. Escitalopram is approved for the treatment of a number of anxiety disorders. It seems to be well tolerated and induces few or no discontinuation symptoms, and may be considered a first-line agent for the pharmacotherapy of obsessive–compulsive disorder, generalised anxiety disorder, panic disorder and social phobia. Further studies are needed to define its activity in impulse control disorders.
Symmetrical Biphasic TENS Waveform for Treatment of Back Pain (1987)

A TENS using an experimental, symmetrical biphasic waveform was used to treat 65 back pain patients. The control was conventional high rate Transcutaneous Electrical Nerve Stimulator (TENS) administered every other day in a 5-day crossover study. Visual analog scales were used to evaluate pain before and after treatment. Daily patient interviews were used to compare the length of carryover pain relief after treatment. The carryover pain relief with the new waveform was found to be longer, p < 0.01. Patients preferred the new waveform over the conventional TENS, p < 0.05. The new waveform pain relief was greater, but was not statistically significant, p = 0.07. The sensation of the new waveform in its present form was judged slightly less pleasant by some patients.
GAN-Sec: Generative Adversarial Network Modeling for the Security Analysis of Cyber-Physical Production Systems (2019)

Cyber-Physical Production Systems (CPPS) will usher a new era of smart manufacturing. However, CPPS will be vulnerable to cross-domain attacks due to the interactions between the cyber and physical domains. To address the challenges of modeling cross-domain security in CPPS, we are proposing GAN-Sec, a novel conditional Generative Adversarial Network based modeling approach to abstract and estimate the relations between the cyber and physical domains. Using GAN-Sec, we are able to determine if various security requirements such as confidentiality, availability, and integrity are met. We provide a security analysis of an additive manufacturing system to demonstrate the applicability of GAN-Sec.
Mesoporous silica supported ytterbium as catalyst for synthesis of 1,2‐disubstituted benzimidazoles and 2‐substituted benzimidazoles (2018)

The benzimidazole ring is an important pharmacophore in contemporary drug discovery. Thus, effort to identifying new compounds containing benzimidazole scaffolds have gained much attention in recent years. In the present study, MCM‐41 type mesoporous silica with large pore ( l ‐MSN) supported ytterbium was successfully prepared by wet impregnation method. Among rare earth metal salts, ytterbium triflate has already been widely investigated as a catalyst in organic synthesis but less toxic ytterbium oxide has yet to be explored. Relatively high abundance and low cost of ytterbium with respect to many catalytically active metals (e.g. Pd, Au, Ru, Ir, Pt) offer an opportunity to develop sustainable catalysts for organic conversions. The catalyst has been characterized by various techniques including nitrogen adsorption, FT‐IR, TEM, SEM, EDX technique and elemental mapping. The obtained materials exhibit high surface area and a narrow distribution of mesoporosity. The catalytic performance of the Yb@ l –MSNs was tested by synthesis of 1,2‐disubstituted benzimidazoles and 2‐substituted benzimidazoles through the coupling of aldehydes with o ‐phenylenediamine. The catalyst resulted in excellent yields in short reaction times and the reaction showed tolerance toward both electron‐donating and electron‐withdrawing functional groups at room temperature. A particularly interesting finding was the solvent selectivity of this reaction; namely, 1,2‐disubstituted benzimidazoles generated as major product in water‐ethanol, while the 2‐substituted benzimidazoles was generated exclusively in non‐polar solvents like toluene.
Multiwavelets in ℝ n with an Arbitrary Dilation Matrix (2003)

We present an outline of how the ideas of self-similarity can be applied to wavelet theory, especially in connection to wavelets associated with a multiresolution analysis of $${\mathbb{R}^n} $$ allowing arbitrary dilation matrices and no restrictions on the number of scaling functions.
Single Nanoparticle Growth from Nanoparticle Tracking Analysis: From Monte Carlo Simulations to Nanoparticle Electrogeneration (2018)

Abstract By scrutinizing the trajectory of individual nanoparticles (NPs) in solution, NP tracking analysis (NTA) allows sizing individual NPs and providing meaningful complementary information to single NP electrochemistry. Herein, a model is developed to extend NTA to allow dynamic NP sizing and to analyze the kinetics of growth of NPs in solution. Interpreting the NP trajectories as scaled Brownian motion, Monte Carlo simulations produce stochastic trajectories of growing NPs (under diffusion‐controlled growth). These trajectories are grounds for determining a strategy to estimate the growth parameters of individual NPs from the time evolution analysis of the mean square displacement (MSD) curves. In particular, we evaluate the accuracy and precision of the parameter estimates from MSD analysis. In addition, the strategy is illustrated to depict the homogeneous electrosynthesis of silver NPs from the oxidation of a sacrificial Ag ultramicroelectrode (UME) in Fe 2+ solution.
Antibacterial evaluation of Copaifera langsdorffii oleoresin and its isolated compounds against multiresistant bacteria (2014)

The present work aimed to evaluate the antibacterial activities of the Copaifera langsdorffii oleoresin and its isolated compounds to contribute to the development of drugs that can avoid the bacterial growth underlying multiresistant and other bacterial diseases. ent-Copalic acid (1) was the most promising agent against the majority of the tested bacteria, with Minimal Inhibitory and Bactericidal Concentrations (MIC and MBC) values ranging from 6.25 to 31.25 µg mL-1. Kinetic studies revealed that 1, at their MBC values, eliminates all the tested bacteria within 24h of incubation. Inhibition of bacterial growth starts to decrease after 12h of incubation and the bactericidal potential of 1 becomes evident between 18 and 24h. Compound 1 displayed Minimum Inhibitory Concentrations of Biofilm (MICB50) ranging from 62.5 to 2000 µg mL-1 against all tested bacteria. It is possible to conclude that, among all the tested compounds, the diterpene 1 was the most active, especially against Gram-positive multiresistant bacteria and represents a potential drug to treat infections caused by multiresistant bacteria both in the planktonic and sessile mode.