gebhart/patrepeval huggingface dataset:
Strengthening the Environment for Islamic Finance in Hong Kong – A Regulatory Analysis (2023)

This contribution deals with fiscal sustainability understood as “avoiding an excessive increase in government liabilities – a burden on future generations – while ensuring that the government can deliver the necessary public services, including the necessary safety net in times of hardship, and to adjust policy in response to new challenges”. The article aims the analysis of the legal framework for fiscal rules at the level of the EU and the national level in France and Poland. The research problem is to answer the question of how and whether the French and Polish regulations meet the international regulations in the field of fiscal sustainability. According to the research hypothesis, both countries only partially meet the EU requirements. The article is based on the detailed desk research method requiring analysis of the literature, statistical data, and EU and national legal regulations. The general conclusion is that both countries do not fully comply with EU commitments regarding fiscal rules.
Blueberry Varieties for Florida (1969)

Blueberries are native to eastern North America. They are one of the few crop plants that originated here. The rabbiteye blueberry (Vaccinium ashei) occurs mostly in certain river valleys in northern Florida and southeastern Georgia. The highbush blueberry (Vaccinium corymbosum) is native in the eastern third of the United States and southeastern Canada. Florida is rich in other native Vaccinium species. The woods and swamps of Florida are populated with at least eight wild blueberry species. No area of the state lacks wild blueberries, except where soil pH is above 6.0. This document is HS967, one of a series of the Department of Horticultural Sciences, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida. Original publication date: March 2004. &#x0D; https://edis.ifas.ufl.edu/hs215
Green synthesis, characterization and anticancer activity of luminescent gold nanoparticles capped with apo-α-lactalbumin (2015)

A green synthesis was developed to prepare protein coated gold nanoparticles (NPs) where apo-α-lactalbumin was used as reducing and stabilizing agent. The NPs are luminescent and non-toxic to normal cells but more toxic to MCF-7 cells over HeLa.
Phase I and pharmacokinetics (PK) of combined erbB1 and erbB2 blockade with OSI-774 (erlotinib; E) and trastuzumab (T) in combination with weekly paclitaxel (P) in patients (pts) with advanced solid tumors (2005)

2000 Background: Co-expression of erbB1 and erbB2 receptors confers a growth advantage in erbB2 overexpressing (+) cancers. Specifically, co-expression alters the normal rapid internalization and inactivation of erbB1, slows dissociation of the erbB1 ligand-receptor complex and degradation of the active receptor. Co-targeting both receptors together may offer a therapeutic advantage over targeting erbB2 alone, especially in T refractory solid tumors. A phase I and PK study was launched to determine the toxicity and recommended dose of continuous daily oral E in patients with erbB2 + cancers along with weekly P and T, especially since T improves survival in combination with chemotherapy. Methods: Eligible pts were treated with escalating doses of E and weekly T IV (2 mg/kg/wk) along with weekly P (starting at 80 mg/m2). MUGA scans were performed at baseline and every 2 cycles (8 weeks). Two schedules- 3 out of 4 weeks and continuous weekly P and T were explored. Results: To date, 16 pts [Breast (14), Colon (1) and Ovary (1)] have received 54 courses [median 2; range 1–13] in 4 cohorts, with E at doses of 50 (n=3), 100 (n=9) and 150 mg (n=4) PO daily for 28-days and P at doses of 80 - 90 mg/m2 weekly for 3 out of 4 weeks. Pts were women with median age -54 yrs [range- 37–75] and PS 0 (4), PS 1 (11) and PS 2 (1). 9 pts received prior T therapy. Dose limiting grade (gr) 3 diarrhea and gr 3 dermatitis was seen in 1 pt at 100 mg of E and 80 mg/m2of P. Other toxicities included gr 2 diarrhea, skin rash, fatigue, neutropenia and alopecia. Significant asymptomatic drop in LVEF was noted in 1 pt after 3 courses, with rapid recovery upon stopping T. One complete and two partial responses have been seen in pts with breast cancers that have failed prior T therapy. Two breast cancer pts experienced stable disease lasting 13 and 6 courses, respectively. Preliminary PK data does not suggest a clinically relevant interaction between the 3 agents. Conclusions: E combined with T and P provides a well-tolerated, targeted therapy with impressive anti-tumor activity in T-refractory breast carcinoma. Dose escalation continues on the continuous dosing schedule. Author Disclosure Employment or Leadership Consultant or Advisory Role Stock Ownership Honoraria Research Funding Expert Testimony Other Remuneration OSI
A trial to assess the efficacy and tolerability of Hyalofill-F in non-healing venous leg ulcers (2003)

This study was sponsored by Fidia Advanced Biopolymers, Italy.
Effets de l'inclinaison naturelle du tronc sur le contrôle de l'équilibre orthostatique, l'initiation de la marche et la marche (2009)

Ce memoire a pour objectif d'etudier les effets de l'inclinaison naturelle du tronc dans le plan sagittal sur le controle de la posture orthostatique, l'initiation de la marche et la marche. Des sujets en bonne sante sont classes en groupes, en mesurant l'angle de leur tronc par rapport a la verticale et en utilisant le modele clinique de Sohier et Haye (1989). Deux etudes preliminaires ont precise la methodologie. Pour l'etude du controle postural, les moments articulaires a la cheville, a la hanche et en L5 ainsi que la position anteroposterieure (AP) du centre de masse du haut du corps par rapport aux hanches permettent d'expliquer les differences de regulation posturale observees entre les groupes, quelle que soit la classification. L'etude de l'initiation de la marche presente les moments articulaires du membre d'appui a la cheville, au genou, a la hanche et en L5 au cours de l'execution du premier pas. Bien que les parametres spatiotemporels, la dynamique du tronc et la composante AP de la force de reaction au sol soient similaires entre les groupes, ces moments presentent des caracteristiques specifiques a l'inclinaison du tronc. L'etude de la phase d'appui de la marche montre que les moments articulaires des membres inferieurs et en L5 sont affectes par l'inclinaison naturelle du tronc et qu'il existe des asymetries entre les membres inferieurs en fin de phase d'appui, quelle que soit la classification. En conclusion, ce memoire montre les effets de l'inclinaison naturelle du tronc sur les trois tâches motrices etudiees. En l'absence de systeme d'analyse gestuelle, le modele clinique apparait etre une alternative interessante a la classification experimentale.
Radial flow hepatocyte bioreactor using stacked microfabricated grooved substrates (2007)

Bioartificial liver (BAL) devices with fully functioning hepatocytes have the potential to provide temporary hepatic support for patients with liver failure. The goal of this study was to optimize the flow environment for the cultured hepatocytes in a stacked substrate, radial flow bioreactor. Photolithographic techniques were used to microfabricate concentric grooves onto the underlying glass substrates. The microgrooves served to protect the seeded hepatocytes from the high shear stresses caused by the volumetric flow rates necessary for adequate convective oxygen delivery. Finite element analysis was used to analyze the shear stresses and oxygen concentrations in the bioreactor. By employing high volumetric flow rates, sufficient oxygen supply to the hepatocytes was possible without an integrated oxygen permeable membrane. To implement this concept, 18 microgrooved glass substrates, seeded with rat hepatocytes cocultured with 3T3-J2 fibroblasts, were stacked in the bioreactor, creating a channel height of 100 microm between each substrate. In this bioreactor configuration, liver-specific functions (i.e., albumin and urea synthesis rates) of the hepatocytes remained stable over 5 days of perfusion, and were significantly increased compared to those in the radial flow bioreactor with stacked substrates without microgrooves. This study suggests that this radial flow bioreactor with stacked microgrooved substrates is scalable and may have potential as a BAL device in the treatment of liver failure.
Structural studies of codeinone reductase reveal novel insights into aldo-keto reductase function in benzylisoquinoline alkaloid biosynthesis (2021)

Benzylisoquinoline alkaloids (BIAs) are a class of specialized metabolites with a diverse range of chemical structures and physiological effects. Codeine and morphine are two closely related BIAs with particularly useful analgesic properties. The aldo-keto reductase (AKR) codeinone reductase (COR) catalyzes the final and penultimate steps in the biosynthesis of codeine and morphine, respectively, in opium poppy (Papaver somniferum). However, the structural determinants that mediate substrate recognition and catalysis are not well defined. Here, we describe the crystal structure of apo-COR determined to a resolution of 2.4 Å by molecular replacement using chalcone reductase as a search model. Structural comparisons of COR to closely related plant AKRs and more distantly related homologues reveal a novel conformation in the β1α1 loop adjacent to the BIA-binding pocket. The proximity of this loop to several highly conserved active-site residues and the expected location of the nicotinamide ring of the NADP(H) cofactor suggest a model for BIA recognition that implies roles for several key residues. Using site-directed mutagenesis, we show that substitutions at Met-28 and His-120 of COR lead to changes in AKR activity for the major and minor substrates codeinone and neopinone, respectively. Our findings provide a framework for understanding the molecular basis of substrate recognition in COR and the closely related 1,2-dehydroreticuline reductase responsible for the second half of a stereochemical inversion that initiates the morphine biosynthesis pathway.
Multiparalleling of IGBT inverters for high output power (1998)

The use of IGBT inverters for variable speed drives has gained tremendous popularity in recent times, because of the many advantages offered by this technology. Excellent control performance, high reliability and high efficiency as well as low cost and easy maintenance are the most important benefits. The output power of IGBT inverters in the low voltage range, however, is limited to some hundred kW using the IGBTs available today. To increase the output power of IGBT inverters, the method of paralleling complete inverter units provides an advantageous solution. In this paper, a multiparallel system is presented, which allows up to eight IGBT inverters to be connected in parallel and which offers many very advantageous features. An extremely high output power of some MW can be achieved in the low voltage range.
A MU-MIMO CQI Estimation Method for MU-MIMO UEs in LTE Systems (2012)

This paper addresses a method to estimate the multi user channel quality indicator (CQI) from the reported rank 1 single user CQI in LTE systems. We investigate the relationship between the multi user CQI and the channel condition. Based on that, we propose an updating mechanism where the estimated multi user CQI is varied according to the reported channel condition i.e. the rank 1 single user CQI. System performance of the proposed scheme is compared with the conventional fixed offset single user CQI estimation. System level simulation results show the efficiency of our proposed scheme with respect to both the enhancement in the system level performance and uplink overhead reduction. Using the statistic metrics derived from the system level simulation, we highlight the importance of having an accurate multi-user CQI estimation. The results illustrate how the multi user CQI information influence the packet scheduling and link adaptation decisions and ultimately the overall system performance.
SiC/Mg multilayer coatings for SCORE coronagraph: long term stability analysis (2011)

SiC/Mg multilayers have been used as coatings of the Sounding-rocket CORonagraphic Experiment (SCORE) telescope mirrors launched during the NASA HERSCHEL program. This materials couple has been largely studied by researchers since it provides higher performances than a standard Mo/Si multilayer; the SCORE mirrors show in fact a peak reflectance of around 40% at HeII 30.4 nm. Nevertheless, long term stability of this coating is an open problem. A study on the aging and stability of this multilayer has been carried on. SiC/Mg multilayer samples characterized by different structural parameters have been deposited. They have been measured just after deposition and four years later to verify degradation based on natural aging. Experimental results and analysis are presented.
Generalized weighted crosstalk for DWDM systems with cascaded wavelength-selective switches (2012)

A generalized method for estimating penalties from spectrally-shaped crosstalk in cascaded multi-port WSS networks is derived, incorporating effects of ASE, signal filtering, and crosstalk filtering. Experiments in a 4-WSS cascade validate the proposed methodology.
Progress in aggregation‐induced emission‐active fluorescent polymeric hydrogels (2021)

Abstract Aggregation‐induced emission (AIE)‐active fluorescent polymeric hydrogels (FPHs) are the marriage of AIE‐active materials and polymeric hydrogels. Different from the widely studied AIE‐active materials that are primarily used in solution or dry solid state, they feature a three‐dimensional crosslinked polymer network that can absorb water without dissolving. Consequently, they are known to bear many advantageous properties such as soft wet nature, tissue‐like mechanical strength, biocompatibility, biomimetic self‐healing feature, facilely tailored structure, as well as responsive fluorescence and volume/shape changes, thus representing a promising category of luminescent materials with many frontier uses. This Review is intended to give a systematic summary of the recent progress in this young but flourishing research area, with particular focus on their design and preparation. Current challenges and future outlooks in this field are also discussed in order to attract new interests and inspire more efforts.
How Durable Is Total Pancreatectomy and Intraportal Islet Cell Transplantation for Treatment of Chronic Pancreatitis? (2019)

This represents the first and largest series to examine long-term outcomes (10 years or more) in TPIAT patients. In our series, this dual procedure produced durable pain relief and sustained islet graft function, even past 10 years postoperatively.
Efficacy and feasibility of the submuscular implantation technique for an implantable cardiac electrical device. (2014)

We consider that the novel method of sub-pectoralis major muscle device implantation described here minimizes the risk of the skin breakdown and improves the patient's quality of life.
Puig i Cadafalch (J.). La géographie et les origines du premier art roman. 1935 (1935)

M. A. Puig i Cadafalch (J.). La géographie et les origines du premier art roman. 1935. In: Bulletin Monumental, tome 94, n°2, année 1935. p. 267.
Antimicrobial and Antifouling Hydrogels Formed In Situ from Polycarbonate and Poly(ethylene glycol) via Michael Addition (2012)

A novel class of antimicrobial cationic polycarbonate/PEG hydrogels are designed and synthesized by Michael addition chemistry. These hydrogels demonstrate strong broad-spectrum antimicrobial activities against various clinically isolated multidrug-resistant microbes. Moreover, they exhibit nonfouling properties and prevent the substrate from microbial adhesion. These antimicrobial and antifouling gels are promising materials as catheter coatings and wound dressings to prevent infections.
Fault analysis based on innovative watertight model method (2017)

This paper, presents a novel method to evaluate the fault seal properties from a watertight model, obtained directly from seismic data using a dense grid of horizon patches. The watertight geological model is obtained from a set of faults and a grid of numerous horizon patches computed for each seismic polarity. In this approach, any change made to stratigraphic or structural units can be directly applied to the model. The objective is to define levels of reservoir at a very fine scale and understand their juxtaposition onto the fault plane to identify potential leakage. We have compared various fault properties using a relative geological time model and the watertight model. Whereas the relative geological time allows computing the vertical throw at a seismic sample resolution, the watertight model allows superimposing the reservoir levels across the fault at various scales and therefore obtaining an Allan diagram. This was applied on a North Sea case study, where the sealing properties could be characterized in the Jurassic level, despite the poor data quality. These properties could be at a later stage integrated in a geocellular grid for reservoir simulation applications. Presentation Date: Wednesday, September 27, 2017 Start Time: 9:20 AM Location: 350D Presentation Type: ORAL
Microphone array system for speech enhancement in a motorcycle helmet (2005)

In this report a real case study of the sound environment within a helmet while driving motorcycle is investigated. A solution to perform speech enhancement is proposed for the purpose of mobile speech communication. A microphone array, mounted onto the face shield in front of the user&amp;apos;s mouth, is used to capture the spatio-temporal properties of the acoustic wave ¯eld inside the helmet. The power of the spatially spread noise within the helmet is small when standing still while it may heavily exceed the power of the speech when driving at high speeds. This will result in dramatically reduced speech intelligibility in the communication channel. The highly dynamic noise level imposes a challenge for existing speech enhancement solutions. We propose a subband adaptive system for speech enhancement which consists of a soft constrained beamformer in cascade with a signal-to-noise ratio dependent single microphone solution. The beamformer make use of a calibration signal gathered in the actual environment from the speaker&amp;apos;s position. This calibration procedure e±ciently captures the acoustical properties in the environment. Evaluation of the beamformer and the single microphone algorithm, both as either parts by them selves and as a cascaded structure, together with the optimal subband Wiener solution is presented. It is shown that a cascaded combination of the calibrated subband beamforming technique together with the single channel solution outperforms either one by it self, and provides near optimal results at all noise levels.
The Power of Proofs-of-Possession: Securing Multiparty Signatures against Rogue-Key Attacks. (2007)

Multiparty signature protocols need protection against rogue-key attacks, made possible whenever an adversary can choose its public key(s) arbitrarily. For many schemes, provable security has only been established under the knowledge of secret key (KOSK) assumption where the adversary is required to reveal the secret keys it utilizes. In practice, certifying authorities rarely require the strong proofs of knowledge of secret keys required to substantiate the KOSK assumption. Instead, proofs of possession (POPs) are required and can be as simple as just a signature over the certificate request message. We propose a general registered key model, within which we can model both the KOSK assumption and in-use POP protocols. We show that simple POP protocols yield provable security of Boldyreva’s multisignature scheme [11], the LOSSW multisignature scheme [28], and a 2-user ring signature scheme due to Bender, Katz, and Morselli [10]. Our results are the first to provide formal evidence that POPs can stop rogue-key attacks.
Base-composition profiles for ubiquitous and tissue-specific genes with and without start CpG islands (2011)

<b>Copyright information:</b>Taken from "Promoter features related to tissue specificity as measured by Shannon entropy"Genome Biology 2005;6(4):R33-R33.Published online 29 Mar 2005PMCID:PMC1088961.Copyright © 2005 Schug et al.; licensee BioMed Central Ltd. Data is for human genes; similar patterns were observed in mouse. Ubiquitous genes with a CpG island; tissue-specific genes with a CpG island; ubiquitous genes with no CpG island; and tissue-specific genes with no CpG island. Note differences in upstream C+G content, peak sizes at TATA box (-35 bp) and initiator positions, and downstream C versus G differences.
Transient, powerful pressures are generated in the brain by a rotational acceleration impulse to the head (2005)

A rotational acceleration impulse to a head, as occurs at traffic accidents, sport injuries, assaults and falls, induces a diffuse brain damage that eventually could result in persistent neuropsychiatric deficits and neurodegeneration. Emphasis has been concentrated on the relative motion of the brain inside the skull during head impact, whereas less attention has been paid to whether intracranial pressure changes are generated and, if so, the implications thereof. In the present experimental study we investigated in an animal model system, based on rabbits, if a sagittal, anterior-posterior rotational acceleration of a head generated intracranial pressure changes, recorded by fibre optic pressure sensors, inserted ipsilaterally in the parieto-temporal and the occipital lobes. Two levels of rotational acceleration were used in the experiments; one higher, corresponding to the threshold limit for moderate diffuse brain injury, and one lower, close to being noninjurious. Several pressure recordings were performed in each rabbit at the two acceleration levels. The pressure recordings invariably revealed the same general characteristics of rapid, positive and negative pressures within the brain, with variations in amplitude and duration, lasting for up to 10 ms. A major finding was the generation of powerful negative pressures, as low as 0.3 bars in absolute pressure. The most prominent difference in amplitudes of the negative peak pressures between the two applied acceleration levels was demonstrated at the parieto-temporal location. The presented pressure recordings are the first to disclose the generation of transient, powerful intracerebral pressures at rotational acceleration of the head, which must be considered in studies of brain injury generation and distribution as well as prevention.
Efficacy and safety of autologous peripheral blood stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia (2017)

Trial registration number UMIN000026445.