gebhart/patrepeval huggingface dataset:
(Invited) Development on Self-Assembly Technique for Arrangement of Chemically Synthesized FePt Nanoparticles (2011)

This paper reviews our study of bit patterned media (BPM) using L10 (face centered tetragonal)-FePt nanoparticles. For the practical use of L10-FePt nanoparticles to BPM, some breakthroughs are required: a highly ordered two-dimensional array of nanoparticles on a substrate, a controlled orientation of the axis of easy magnetization in vertical direction on a substrate. Previously, we reported about the achievement for uniformity FePt nanoparticles by controlling chemical synthesis conditions. Moreover, we confirmed the selective chemical interaction Pt in the surface of FePt nanoparticles and SH group with (3-mercaptopropyl)tri-methoxysilane (MPTMS). This study presented a new hybrid technique combining the selective chemical bonding and a substrate with a geometrical grid in order to control the array of FePt nanoparticles with uniform direction of their magnetization. We succeed in preparing uniform array of nanoparticles on geometrical grid with size of 200 nm square prepared using ultraviolet nanoimprint lithography (UV-NIL).
Prolongation and shortening of action potentials by electrical shocks in frog ventricular muscle (1994)

Effects of electrical shocks on myocardium are important for defibrillation. We measured effects of shocks (5 ms, 1-40 V/cm) in isolated frog ventricular strips. We recorded contraction strength and intracellular action potential (AP) with a shock-voltage cancellation technique to allow recordings immediately after shocks. Shocks of > or = 5 V/cm produced a dose- and latency-dependent prolongation of the AP ongoing during the shock. Stronger shocks of 28-40 V/cm decreased the duration, maximum diastolic potential, amplitude, and maximum rate of rise of the phase zero depolarization of paced APs that began after the shock. The contraction strength increased 43 and 59% during the 10 s after the stronger shocks. The transmembrane potential was shifted toward 0 mV immediately after the stronger shocks. We concluded that weak or strong shocks prolong the AP ongoing during the shock, whereas sufficiently strong shocks also shorten APs that begin after the shock. AP prolongation and shortening may be important for defibrillation and acceleration of tachycardia after failed cardioversion shocks.
Wafer Scale Synthesis and High Resolution Structural Characterization of Atomically Thin MoS2 Layers (2014)

Synthesis of atomically thin MoS 2 layers and its derivatives with large‐area uniformity is an essential step to exploit the advanced properties of MoS 2 for their possible applications in electronic and optoelectronic devices. In this work, a facile method is reported for the continuous synthesis of atomically thin MoS 2 layers at wafer scale through thermolysis of a spin coated‐ammonium tetrathiomolybdate film. The thickness and surface morphology of the sheets are characterized by atomic force microscopy. The optical properties are studied by UV–Visible absorption, Raman and photoluminescence spectroscopies. The compositional analysis of the layers is done by X‐ray photo­emission spectroscopy. The atomic structure and morphology of the grains in the polycrystalline MoS 2 atomic layers are examined by high‐angle annular dark‐field scanning transmission electron microscopy. The electron mobilities of the sheets are evaluated using back‐gate field‐effect transistor configuration. The results indicate that this facile method is a promising approach to synthesize MoS 2 thin films at the wafer scale and can also be applied to synthesis of WS 2 and hybrid MoS 2 ‐WS 2 thin layers.
Absorption rapide de liquide dans un réseau capillaire uniforme (2017)

Affiche présentée dans le cadre du Colloque de l'ARC, «Des racines et des ailes pour la recherche collégiale», dans le cadre du 85e Congrès de l’Acfas, Université McGill, Montréal, les 8 et 9 mai 2017.
ChemInform Abstract: High Activation of Carbonyl Groups with Bidentate Lewis Acid Catalysts (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
COMPARISON OF DNA EXTRACTION PROTOCOLS ON FROZEN STORED BLOOD SAMPLES (2014)

Two major obstacles encountered when extracting DNA from a large number of samples are the cumbersome methods of deproteinising cell digest with the hazardous-toxic organic solvent (phenol and chloroform) and incomplete recovery of aqueous phase leading to loss of DNA. Phenol-Chlorof9rm extraction is compared with high salt deproteinisation procedure. Materials and Methods From deoni cattle of Maharastra region. 10 ml blood was collected in heparinised veacutainer (Becton- Dikison, USA). The blood samples were stored at-200C until processed. Eighteen samples were thawed in water at ambient, temperature. Thawed samples were decanted in 50-ml sterile polypropylene centrifuge tube and double volume of lysis solution (0.17 MN4HCl). added mixed well, centrifuged and supernatant removed. Repeated this step again. The white pallet was re-suspended in 54 ml SE buffer (75mM/NaCl 2mM EDTA) with proteinase-K 20 mg/ml (Boehringer Mannheim, Germany) and 20 % SDS at a final concentration of 0.2 mg/ml and 1 %. respectiely. The tubes were incubated in water-bath at 600C over night with periodical shaking. Six samples were randomly allotted to three different protocols for DNA extraction. Protocol I- (Meniatis et al., 1982): Added equal volume of phenol: chloroform: isoamyl (25:24:1) to the samples. Mixed thoroughly and centrifuged. Aqueous phase was saved and to the 1/10 volume of 3 M sodium acetate was added. DNA was precipitated by adding equal volume of
Ergonomic Evaluation and Design of Handheld Medical Devices (2006)

Ergonomic principles can play an important role in the evaluation and design of handheld medical devices. Traditionally, the process involves identifying gaps between worker capacities and the requirements of the task and tool, with the ultimate goals of preventing pain and disability, and improving productivity. Ergonomic analysis entails measurement of factors that affect the demands as people interact with equipment to achieve one or more goals. The elements of the interaction between humans and machines includes objectives, machine components, human components, and interactions between the human, machine, and an environment, which collectively provide a framework for understanding what people do and why. The goals include why the system exists and what the user, customer, employer, investor, or other concerned party wishes to derive from the system. For example, the objective for a system of measuring a patient’s blood pressure might be: “Measure blood pressure with an error less than ±5 mm Hg 90% of the time.”
Decoding climate adaptation governance: A sociotechnical perspective of U.S. airports (2021)

Inadequate governance is considered a major barrier for implementing policy, particularly those concerning global and complex challenges such as climate change adaptation. Literature in adaptation policy point to the lack of methods that monitor and assess how decision-making takes place and by whom. Based on a review of over 200 policy documents, this article benchmarks for the first time, the current airport climate adaptation regime in the United States and applies a sociotechnical system framework to scrutinize institutional capacity to address climate change impacts. An innovative policy review system is designed to decode how airport policies create conditions to use climate data as decision-relevant information and produce adaptation actions. Potential climate-cognizant policies are identified and characterized based on their target, timescale, and governance mode. Review results show that the assumption of climate stationarity is widespread. However, there is high potential for technical and, especially, organizational airport policies to incorporate climate science and adaptation pathways. Results also uncover governance barriers related to institutional path-dependence that include: (1) conflicting rationales between adaptation and reliability values, and (2) overpowering technical policies and market governance. These barriers perpetuate scale-mismatch between airport policies and expected impacts from climate change. Finally, we highlight the latent capacity for collaborative governance to advance adaptation regimes in airports and other multiscalar complex infrastructure systems. Our proposed methods and review results identify pathways to enhance institutional capacity for designing and operationalizing transformative adaptation policies.
Simulation of fluorine implant effects in metal-gate FD-SOI and MuGFET (2007)

Fluorine (F) implantation creates negative charges at the Si/SiOa interface in FDSOI transistors[l]. This paper describes simulati n of the influence of F Implant on Threshold Voltage(Vth) for Metal Gate FDSOI and MuGFETs using FEMLAB. The origin of the large Vth shift observed in planar FDSOI due to is the creation of negative charge states in the BOX by the F implant. F implant is a suitable approach for planar FDSOI SoC integration with single work function (WF) metal gate, but NOT for MuGFETs.
Hépatite C : le traitement (1999)

En France, l’histoire naturelle de l’hepatite chronique C est mieux connue, avec une augmentation previsible de la mortalite imputable a cette epidemie pendant les vingt prochaines annees [1, 2]. L’amelioration spectaculaire de l’efficacite des traitements ces dix dernieres annees et l’augmentation du depistage laissent cependant esperer que ces previsions seront reduites a la baisse. L’hepatite C est une maladie potentiellement grave et les traitements dont on dispose sont efficaces grâce a deux acquisitions therapeutiques recentes. L’emergence de la bitherapie, d’une part, qui permet une remission virologique prolongee chez presque la moitie des patients et les met theoriquement a l’abri de la cirrhose et de ses complications. D’autre part, la constatation, meme chez les non-repondeurs, d’un ralentissement de la vitesse de progression de la fibrose sous interferon qui permet theoriquement de retarder la constitution de la cirrhose qui demeure l’element pejoratif de la maladie. Les benefices attendus du traitement sont, pour la cirrhose, une reduction de moitie de l’incidence annuelle et pour le CHC une reduction des deux tiers. Les patients necessitant imperativement un traitement sont ceux susceptibles d’avoir une evolution fibrosante, ceux ayant des manifestations extrahepatiques genantes et ceux qui peuvent transmettre le virus. En pratique, l’indication therapeutique est indiscutable a partir d’un score de fibrose F2. Pour les scores moins eleves l’indication se discute en fonction de certains criteres (duree depuis la contamination, âge du patient, immunosuppression, manifestations extrahepatiques, professions de sante, toxicomanes avec conduites contaminatrices, prostitution). L’evolution future des traitements et l’avenement de nouvelles molecules ayant un meilleur rapport benefice/risque inciteront peut-etre a traiter tous les sujets infectes pour eliminer les reservoirs de virus.
Noninvasive Prenatal Diagnostic Assay for the Detection of β‐Thalassemia (2006)

The development of a noninvasive method for detection of beta-thalassemia in the population of Cyprus is based on the detection of paternally inherited single nucleotide polymorphisms (SNPs) as well as beta-thalassemia (beta-thal) mutations. We selected 11 informative SNPs for the Cypriot population linked to the beta-globin locus. Two different approaches were used: allele-specific polymerase chain reaction (AS-PCR) and the arrayed primer extension (APEX) method. The AS-PCR approach is being standardized, and the method was applied in two families. The paternally inherited allele was noninvasively detected with the AS-PCR approach on maternal plasma. Some preliminary tests were performed with the APEX method on genomic DNA of parents carrying the beta-thal mutation.
Clinical activity and cardiac tolerability of non-pegylated liposomal doxorubicin in breast cancer: a synthetic review. (2012)

Anthracycline-containing regimens have demonstrated significant disease-free and overall survival benefits in the adjuvant setting and also provide palliative benefit in metastatic disease. . Over the past two decades, an increasing proportion of patients have been exposed to adjuvant anthracyclines with concomitant reduction in their use for palliation, as a result of concerns regarding efficacy and cumulative anthracycline-associated cardiotoxicity, as well as the availability of other systemic chemotherapeutic options. This report reflects the consensus view of a meeting of oncologists, pharmacologists and cardiologists held in Florence, Italy, on April 30, 2010. The objectives of the meeting were to review the role and limits of conventional anthracyclines in the treatment of breast cancer, to provide recommendations for the use of novel anthracycline formulations, such as non-pegylated liposomal doxorubicin (NPLD), and to identify potential future indications for NPLD that warrant further research.
Emergence of Heptazine-Based Graphitic Carbon Nitride within Hydrogel Nanocomposites for Scarless Healing of Burn Wounds (2020)

Graphitic carbon nitride (gCN) has only recently experienced a renaissance in a myriad of domains despite existing as a long-established material described in the chemical literature. Notwithstanding the upturn, their conventional synthesis at extremely high temperatures yielding limiting compositions stands in the way of achieving a paradigm shift in gCN fabrication. With the ultimate goal of surpassing these hurdles, we utilize N-doped carbon nanosheets (N-CNS) as a filler in free-radical-mediated aqueous copolymerization. By dispersing N-CNS in a polymer matrix, high-performance mechanically robust composites could be developed and tailored to individual applications. As-synthesized hydrogel nanocomposite systems are used to decode the balance for emulating evolutionary accomplishments of nature’s nanocomposites like the “abalone’s nacre”. At a lower concentration (0.05%), N-CNS disperse homogeneously and interact intimately with the polymer matrix forming an “interphase” zone around individual nanofillers dramatically affecting the mobility of polymer chains to yield sheet architectures. On increasing the filler concentration (0.3%), the intercalation phenomenon gets perturbed due to an intrinsically oriented aggregation of nanofiller giving rise to a surge in entropy that leads to conspicuous buckling and tubular aggregates. At the interfacial regime, the poly(acrylic acid) domains come in closer proximity to the hydrophobic cages of N-CNS, and a nanoconfinement effect exerts high pressure manifesting acid-catalyzed condensation of melamine units to form, for the first time, quasi-two-dimensional heptazine-gCN (h-gCN) within hydrogel nanocomposites. Polymer properties are enhanced by the addition of N-CNS through complex interfacial interactions and the unique distributions of internanofiller distances. Endowed with mechanical properties that closely mimic natural skin and combined with the repurposed drug “losartan”, these hydrogel nanocomposites offer scarless healing of second-degree burns.
Studies on α-ANP and its effect on blood pressure in chronic hemodialysis patients (1989)

維持透析患者26名を対象として透析日及び非透析臼の2回にわたり血漿α-ANP (ヒト心房性Na利尿ペプタイド), 血漿レニン活性 (PRA) を測定し, 平均血圧 (MAP), 体重増加率との関係を検討し, 血圧調節への影響についで考察した.Dry weightの3%以内の体重増加例では血漿α-ANP濃度はほぼ正常を示したが, 3%以上の体重増加例では明らかに体重増加量に比例した上昇を示した (p=0.662, P<0.001).しかしながら, 体重増加による血圧上昇との比較では血圧上昇抑制効果は認められず, この結果はPRA 2.5ng/ml/hr以上の高レニン血漿例においても, PRA 2.5ng/ml/hr未満の非高レニン血漿例における比較でも同様であった.
A new method to support in-home mobile devices supervision (2007)

Recently, there have been numerous researches into domestic technologies to design the pervasive smart home. For home networks, we believe that ubiquitous computing requires a global-scale system that is zero-conf, self-managed and self- controlled. The emergence of different home automation technologies especially the wireless ones has introduced new challenges for home management. In the home, several appliances such a TV, a PC, a camcorder etc. can interoperate through the use of the UPnP architecture. With UPnP, devices can announce their presence, distribute information about their services, and send or respond to various control commands from other devices. Although the UPnP architecture leverages existing standards such as TCP/IP, HTTP and XML, it cannot directly handle scenarios where an UPnP device becomes mobile. Mobility brings new requirements and is becoming a key characteristic. In this paper we propose a system level architecture to provide mobility support to UPnP in-home devices.
Multi-Order Quasi-Phase Matching for Generation of Pure Heralded Single Photons (2022)

We experimentally demonstrate multi-order quasi-phase-matching conditions for spectral shaping of photon pairs produced by spontaneous parametric downconversion. Incorporated with a group-velocity matching condition, our multi-order quasi-phase-matching scheme generates single photons high spectral purity.
Delineation of a lactococcal conjugation system reveals a restriction‐modification evasion system (2023)

Plasmid pUC11B is a 49.3-kb plasmid harboured by the fermented meat isolate Lactococcus lactis subsp. lactis UC11. Among other features, pUC11B encodes a pMRC01-like conjugation system and tetracycline-resistance. In this study, we demonstrate that this plasmid can be conjugated at high frequencies to recipient strains. Mutational analysis of the 22 genes encompassing the presumed pUC11B conjugation cluster revealed the presence of several genes with essential conjugation functions, as well as a gene, trsR, encoding a putative transcriptional repressor of this conjugation cluster. Furthermore, plasmid pUC11B encodes an anti-restriction protein, TrsAR, which facilitates higher conjugation frequencies when pUC11B is transferred into recipient strains containing Type II or Type III RM systems. These findings demonstrate how RM mechanisms can be circumvented when they act as a biological barrier for conjugation events.
Low-Temperature Drop-on-Demand Reactive Silver Inks for Solar Cell Front-Grid Metallization (2016)

Formation of high-conductivity metal contacts at low temperatures expands optoelectronic device opportunities to include thermally sensitive layers, while reducing expended thermal budget for fabrication. This includes high-efficiency silicon heterojunction solar cells with intrinsic amorphous silicon layers. Efficiencies of these cells are limited by series resistance; the primary cause of this is the relatively high resistivity of the low-temperature silver paste used to form front-grid metallization. In this paper, we report the formation of highly conductive features by drop-on-demand printing of reactive silver ink (RSI) at a low temperature of 78 °C, resulting in media resistivities of 3-5 μΩ·cm. When used as a front grid on a silicon heterojunction solar cell, RSI fingers give cell series resistance of 1.8 Ω·cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> (without optimization of the process), which is impressively close to 1.1 Ω·cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> for our commercially available screen-printed low-temperature silver paste metallization. We present here the promising first results of RSI as metallic finger for photovoltaics, which upon optimization of design parameters has the potential to outperform the screen-printed low-temperature silver paste counterpart.
The Natural Cytotoxicity Receptor 1 Contribution to Early Clearance of Streptococcus pneumoniae and to Natural Killer-Macrophage Cross Talk (2011)

Natural killer (NK) cells serve as a crucial first line of defense against tumors, viral and bacterial infections. We studied the involvement of a principal activating natural killer cell receptor, natural cytotoxicity receptor 1 (NCR1), in the innate immune response to S. pneumoniae infection. Our results demonstrate that the presence of the NCR1 receptor is imperative for the early clearance of S. pneumoniae. We tied the ends in vivo by showing that deficiency in NCR1 resulted in reduced lung NK cell activation and lung IFNγ production at the early stages of S. pneumoniae infection. NCR1 did not mediate direct recognition of S. pneumoniae. Therefore, we studied the involvement of lung macrophages and dendritic cells (DC) as the mediators of NK-expressed NCR1 involvement in response to S. pneumoniae. In vitro, wild type BM-derived macrophages and DC expressed ligands to NCR1 and co-incubation of S. pneumoniae-infected macrophages/DC with NCR1-deficient NK cells resulted in significantly lesser IFNγ levels compared to NCR1-expressing NK cells. In vivo, ablation of lung macrophages and DC was detrimental to the early clearance of S. pneumoniae. NCR1-expressing mice had more potent alveolar macrophages as compared to NCR1-deficient mice. This result correlated with the higher fraction of NCR1-ligand(high) lung macrophages, in NCR1-expressing mice, that had better phagocytic activity compared to NCR1-ligand(dull) macrophages. Overall, our results point to the essential contribution of NK-expressed NCR1 in early response to S. pneumoniae infection and to NCR1-mediated interaction of NK and S. pneumoniae infected-macrophages and -DC.
Induced Pluripotent Stem Cell Labeling Using Quantum Dots (2013)

Induced pluripotent stem (iPS) cells have received remarkable attention as the cell sources for clinical applications of regenerative medicine including stem cell therapy. Additionally, labeling technology is in high demand for tracing transplanted cells used in stem cell therapy. In this study, we used quantum dots (QDs), which have distinct fluorescence abilities in comparison with traditional probes, as the labeling materials and investigated whether iPS cells could be labeled with QDs with no cytotoxicity. iPS cells could not be labeled with QDs alone but required the use of cell-penetrating peptides such as octaarginine (R8). No significant cytotoxicity to iPS cells was confirmed by up to 8 nM QDs, and the iPS cells labeled with QDs maintained their undifferentiated state and pluripotency. These data suggest that QDs can be used for fluorescence labeling of iPS cells.