gebhart/patrepeval huggingface dataset:
Clinical research of postpartum hemorrhage hysterectomy (2013)

Objective To analyze the clinical data of patients with postpartum hemorrhage hysterectomy,and to explore the eptimal timing of surgery for hysterectomy.Methods Retrospectively analyzed the clinical data of 31 hysterectomy patients in ten years which from January 2002 to December 2011.Results In the 31 patients,placental factor was the leading cause of hysterectomy(51.61％),and the second factor was uterine contraction atony(25.9％).Blood loss was about 1000-6000 ml,the mean blood loss was 4130 ml.All 31 patients were given blood transfusion,the blood transfusion was 800-3800 ml,the average blood transfusion was 2280 ml.Conclusions Hysterectomy is an important measure to treat severe postpartum bleeding and to rescue maternal life; master the operation chance has a vital significance to decrease postoperative complication and reduce maternal mortality.

Key words: 
Postpartum hemorrhage; Hysterectomy; Uterine atony; Operation time
Solvatochromism of novel donor–π–acceptor type pyridinium dyes in halogenated and non-halogenated solvents (2009)

Donor–π–acceptor type pyridinium dyes that have been newly synthesized showed bathochromic shift of the absorption band with decreasing dielectric constant (εr) of solvent (negative solvatochromism), and the bathochromic shifts in halogenated solvents were larger than those in non-halogenated solvents of similar εr values. The influences of halogenated solvents on the large bathochromic shifts are studied on the basis of 1H NMR measurements, semi-empirical molecular calculations (AM1 and INDO/S using the SCRF Onsager model), and absorption spectral measurements of the dyes adsorbed on nanocrystalline TiO2 film immersed in solvents.
Rapid FPGA delay characterization using clock synthesis and sparse sampling (2010)

This paper introduces a set of novel techniques for rapid post-silicon characterization of FPGA timing variability. The existing built-in self-test (BIST) methods work by incrementing the clock frequency until timing failures occur within the combinational circuit-under-test (CUT). A standing challenge for industrial adoption of post-silicon device profiling by this method is the time required for the characterization process. To perform rapid and accurate delay characterization, we introduce a number of techniques to rapidly scan the CUTs while changing the clock frequency using off-chip and on-chip clock synthesis modules. We next find a compact parametric representation of the CUT timing failure probability. Using this representation, the minimum number of frequency samples is determined to accurately estimate the delay for each CUT within the 2D FPGA array. After that, we exploit the spatial correlation of the delays across the FPGA die to measure a small subset of CUT delays from an array of CUTs and recover the remaining entries with high accuracy. Our implementation and evaluations on Xilinx Virtex 5 FPGA demonstrate that the combination of the new techniques reduces the characterization timing overhead by at least three orders of magnitude while simultaneously reducing the required storage requirements.
Levels of Thermostable Direct Hemolysin Production by Vibrio parahaemolyticus Strains Carrying both tdh and trh Genes (1997)

One hundred and twenty-five strains of Vibrio parahaemolyticus carrying both the tdh and trh genes were selected from the strains isolated from the travelers with diarrhea by an hybridization test using polynucleotide probes. The levels of TDH produced by these strains and the association between the TDH levels and related characteristics in these strains were analyzed. The TDH level varied greatly from strain to strain, but none of the levels was as high as that of the typical Kanagawa phenomenon-positive strains. The strains were classified into "TDH producer" (18 strains), "Low-level TDH producer" (85 strains), and "No TDH producer" (22 strains) based on the results of a modified Elek test and the hemolysis assay on Wagatsuma agar. The highest TDH level achieved by the "TDH producer" was twofold lower than that of the Kanagawa phenomenon-positive strains as assayed by the RPLA method. All strains possessed the toxR gene. The trh1 and trh2 genes were detected in, respectively, 105 and 20 strains, and no correlation existed between the type of the trh gene and the levels of TDH produced. Considerable restriction fragment length polymorphism was observed with the tdh gene-bearing HindIII DNA fragment in different strains, but it was not related with the TDH level.
LLNL Underground-Coal-Gasification Project. Quarterly progress report, July-September 1981 (1981)

We have continued our laboratory studies of forward gasification in small blocks of coal mounted in 55-gal drums. A steam/oxygen mixture is fed into a small hole drilled longitudinally through the center of the block, the coal is ignited near the inlet and burns toward the outlet, and the product gases come off at the outlet. Various diagnostic measurements are made during the course of the burn, and afterward the coal block is split open so that the cavity can be examined. Development work continues on our mathematical model for the small coal block experiments. Preparations for the large block experiments at a coal outcrop in the Tono Basin of Washington State have required steadily increasing effort with the approach of the scheduled starting time for the experiments (Fall 1981). Also in preparation is the deep gasification experiment, Tono 1, planned for another site in the Tono Basin after the large block experiments have been completed. Wrap-up work continues on our previous gasification experiments in Wyoming. Results of the postburn core-drilling program Hoe Creek 3 are presented here. Since 1976 the Soviets have been granted four US patents on various aspects of the underground coal gasification process. These patents are described here, and techniques of special interest are noted. Finally, we include ten abstracts of pertinent LLNL reports and papers completed during the quarter.
Isolation ofPaenibacillussp. and Assessment of its Potential for Enhancing Mineral Weathering (2012)

One mineral-solubilizing bacterial strain designated KT was isolated from a soil in Henan Province, China. The full-length 16S rRNA gene sequence showed 95.2 to 96.7% similarity to the bacteria of the genus Paenibacillus, indicating that the strain KT belonged to the genus Paenibacillus. The potential of this strain to release potassium from silicate minerals was investigated using a potassium-bearing rock as the sole source of potassium to support its growth. After inoculation for 7 days, the concentrations of water-soluble Al, Ca and Fe released from the potassium-bearing rock in active bacterial culture were higher than those from the control with autoclaved inoculum, but the concentration of water-soluble K in active bacterial culture was similar to that in the control. The concentrations of HNO3-extractable Al, Ca, Fe and K from the bacterial culture were also higher than those in the control. These results showed strain KT was able to release potassium from potassium-bearing rock. These results have important implications for extraction of potassium from rocks to support plant growth.
Rearranged EML4-ALK fusion transcripts sequester in circulating blood platelets and enable blood-based crizotinib response monitoring in non-small-cell lung cancer (2015)

Platelets are a valuable source for the non-invasive detection of EML4-ALK rearrangements and may prove useful for predicting and monitoring outcome to crizotinib, thereby improving clinical decisions based on radiographic imaging alone.
Designing coupled free-form surfaces (2010)

The problem of designing optical systems that contain free-form surfaces is a challenging one, even in the case of designing a single surface. Here we present a method for the coupled design of two free-form reflective surfaces that will have a prescribed distortion. On one hand, the method can be described using traditional vectors and matrices, which we do, but it is motivated by viewing the problem in the language of distributions from differential geometry and makes use of the exterior differential systems, which we relegate to an appendix. Example applications are given to the design of a mirror pair that increases the field of view of an observer, a similar mirror pair that also rotates the observer's view, and a pair of mirrors that give the observer a traditional panoramic strip view of the scene.
Enhancement of In Vivo Anticancer Effects of Cisplatin by Incorporation Inside Single-Wall Carbon Nanohorns (2008)

Cisplatin (CDDP) was incorporated inside single-wall carbon nanohorns with holes opened (SWNHox) by a nanoprecipitation method that involved dispersion of CDDP and SWNHox in a solvent followed by the solvent evaporation. The incorporated CDDP quantity increased from the previously reported value of 15 to 46%, and the total released quantity of CDDP also increased from 60 to 100% by changing the solvent from dimethylformamide to water. Concurrently, in vitro anticancer efficiency of CDDP@SWNHox increased to 4-6 times greater than that of the intact CDDP. In vivo, CDDP@SWNHox intratumorally injected to transplanted tumors of mice suppressed the tumor growth more than the intact CDDP. We observed that CDDP@SWNHox adhered to the cell surfaces in vitro and stayed within the tumor tissues in vivo. Therefore, we think that the CDDP released from SWNHox realized high concentrations locally at the cells in vitro and in the tissues in vivo and could efficiently attack the tumor cells. We also found that SWNHox itself had an in vivo anticancer effect, which might increase the anticancer activities of CDDP@SWNHox.
Diffraction of partially coherent X-rays and the crystallographic phase problem (2001)

This paper proposes a new physical method for the partial solution of the crystallographic phase problem by illuminating the crystal with an X-ray beam of limited coherence. The diffraction spots broaden and, if the coherence length of the incident beam is small enough in all three dimensions, the diffraction pattern becomes continuous. Independent information about the structure is then available both at the Bragg angles and at angles that do not satisfy the Bragg conditions. Under certain conditions, the total information is sufficient to solve the crystal structure ab initio. Two prescriptions for producing X-ray beams with limited coherence are given.
Low-divergence laser structures for cost-effective fiber coupling applications (2000)

We report on the design of lasers using waveguide engineering to achieve low divergence emission with high butt-coupling efficiency to single-mode (SMF) and multimode fiber (MMF). A tolerant design principle is introduced for achieving low-divergence normal to the junction using a single epitaxial growth step. The design method is compatible with a wide range of material systems and is demonstrated using a 980-nm laser structure. The full-width half-maximum of the beam is reduced from more than 32/spl deg/ to 21/spl deg/. Direct butt-coupling losses are improved from -10 dB to near -3 dB for ridge waveguide to SMF coupling, while broad area devices coupled to MMF showed coupling efficiencies of >75%.
Lipiodolization for unresectable hepatocellular carcinoma: An analysis of 205 patients using univariate and multivariate analysis (1994)

Since 1982 we have developed and successfully performed lipiodolization on 205 patients with unresectable hepatocellular carcinoma. The 1-, 2-, 3-, 4-, and 5-year survival rates were 55.6%, 31.7%, 16.3%, 8.7%, and 2.9%, respectively, while the median survival was 413 days, and 20 patients survived longer than 3 years after the first lipiodolization. Our study demonstrated that the factors for a comparatively good prognosis were as follows: patient older than 50 years, nodular type hepatocellular carcinoma < 5 cm in diameter, negative tumor invasion of portal vein, < 10 intrahepatic metastases, serum alpha-fetoprotein level < 400 ng/ml, and Okuda stage I. Lipiodolization did not cure hepatocellular carcinoma. It did, however, in this study, achieve a prolongation of the patient's survival.
Antibodies bound to lipid haptens in model membranes diffuse as rapidly as the lipids themselves. (1979)

A pattern photobleaching method has been used to measure the rates of lateral diffusion of fluorescent-labeled specific anti-nitroxide IgG bound with both combining sites to nitroxide-containing phospholipids in liposomal membranes composed of dimyristoyl phosphatidylcholine at 28 degrees C ("fluid"), dipalmitoyl phosphatidylcholine at 32 degrees C ("Solid"), and dipalmitoyl phosphatidylcholine containing 15 or 25 mol% cholesterol ("solid" or "fluid," respectively, at 32 degrees C). The diffusion coefficients of the bound immunoglobulin were found to be the same as those of fluorescent-labeled phospholipids in each case even though these diffusion coefficients range from 10(-11) to 10(-8) cm2/sec. Hapten-containing liposomal membranes of the type studied here have previously been shown to elicit a number of antibody-dependent immune responses. Therefore, this work indicates that membrane-bound but otherwise freely diffusing antibodies are sufficient for these reponses.
Substrate Requirements for Secondary Cleavage by HIV-1 Reverse Transcriptase RNase H (2002)

During and after minus-strand DNA synthesis, human immunodeficiency virus 1 (HIV-1) reverse transcriptase (RT) degrades the RNA genome. To remove RNA left after polymerization, the RT aligns to cut 18 nucleotides in from the 5' RNA end. The enzyme then repositions, making a secondary cut 8 nucleotides from the RNA 5' end. Transfer of the minus strong stop DNA during viral replication requires cleavage of template RNA. Removal of the terminal RNA segment is a special case because the RNA-DNA hybrid forms a blunt end, shown previously to resist cleavage when tested in vitro. We show here that the structure of the substrate extending beyond the RNA 5' end is an important determinant of cleavage efficiency. A short single-stranded DNA extension greatly stimulated the secondary cleavage. Annealing an RNA segment to the DNA extension was even more stimulatory. Recessing the DNA from a blunt end by even one nucleotide caused the RT to reorient its binding, preventing secondary cleavage. The presence of the cap at the 5' end of the viral RNA did not improve the efficiency of secondary cleavage. However, NC protein greatly facilitated the secondary cut on the blunt-ended substrate, suggesting that NC compensates for the unfavorable substrate structure.
Retrieval of temperature and pressure using broadband solar occultation: SOFIE approach and results (2010)

Abstract. Measurement of atmospheric temperature as a function of pressure, T(P), is key to understanding many atmospheric processes and a prerequisite for retrieving gas mixing ratios and other parameters from solar occultation measurements. This paper gives a brief overview of the solar occultation measurement technique followed by a detailed discussion of the mechanisms that make the measurement sensitive to temperature. Methods for retrieving T(P) using both broadband transmittance and refraction are discussed. Investigations using measurements of broadband transmittance in two CO2 absorption bands (the 4.3 and 2.7 μm bands) and refractive bending are then presented. These investigations include sensitivity studies, simulated retrieval studies, and examples from SOFIE.
Radical isomerization during Grignard reagent formation. A quantitative treatment (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRadical isomerization during Grignard reagent formation. A quantitative treatmentJohn F. Garst, John E. Deutch, and George M. WhitesidesCite this: J. Am. Chem. Soc. 1986, 108, 9, 2490–2491Publication Date (Print):April 1, 1986Publication History Published online1 May 2002Published inissue 1 April 1986https://pubs.acs.org/doi/10.1021/ja00269a083https://doi.org/10.1021/ja00269a083research-articleACS PublicationsRequest reuse permissionsArticle Views311Altmetric-Citations40LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Peptides – A source of acrylamide? (2008)

It is commonly accepted that the neurotoxic acrylamide 2 is mainly formed from asparagine (Asn) and a carbonyl compound, e.g. glucose, by a multi-step process (Maillard reaction) during the preparation of food at temperatures exceeding 120°C [1]. Besides this, an alternative route of formation in model studies was found which may contribute to the formation of 2 during baking [2, 3]. We found that thermal degradation of alanine and phenylalanine containing peptides e.g. 1 yielded both 2 and cinnamic amide (3) by a sequence of electrocyclic processes (domino reaction [4]) without the further involvement of a reducing sugar.
D esulforhopalus (2019)

Abstract De.sul.fo.rho'pa.lus. L. pref. de , from; L. neut. n. sulfur , sulfur; Gr. neut. n. rhopalus , cudgel; N.L. masc. n. Desulforhopalus , cudgel‐formed sulfate reducer. Cells are oval‐to‐rod shaped with rounded ends, 1.5–1.8 µm × 3–5 µm. Longer cells occur in the stationary phase. Cells may contain gas vesicles. Occur singly, in pairs, or short chains. Spore formation is not observed. Stain Gram‐negative and nonmotile. Strictly anaerobic, having both a respiratory and a fermentative type of metabolism. Chemoorganoheterotrophs, using propionate, lactate, pyruvate, ethanol, and 1‐propanol as electron donors and carbon sources. Organic substrates are incompletely oxidized to acetate and CO 2 . Chemolithoheterotrophic growth occurs with H 2 as the electron donor in the presence of acetate as carbon source only for D. vacuolatus . Sulfate, sulfite, and thiosulfate serve as terminal electron acceptors and are reduced to H 2 S. Nitrate is reduced to ammonia only by D. singaporensis . In the absence of an external electron acceptor, growth occurs by fermentation of pyruvate. D. singaporensis can grow by fermentation of 2‐aminoethansulfonate (taurine) and by disproportionation of sulfite in the presence of acetate. All species are able to grow in simple defined media containing a reductant. Some species require the vitamins pyridoxamine, nicotinate, and 4‐aminobenzoate for growth. The optimal pH range for growth is 6.8–7.2. At least 5 g NaCl and 1 g MgCl 2 ·6H 2 O per liter are required for growth. Desulfoviridin is absent. The genus Desulforhopalus contains two described species. One species is mesophilic with the optimal temperature range for growth is 20–30°C and another species is moderately psychrophilic with optimal temperature around 18–19°C and the maximum growth temperature 24°C. Occur in the upper part of anoxic marine or brackish sediment. DNA G + C content (mol%) : 48.4–50.6 (LC, genome). Type species : Desulforhopalus vacuolatus Isaksen and Teske 1999, 935 VP (Effective publication: Isaksen and Teske 1996, 167). Taxonomic and Nomenclature Notes According to the List of Prokaryotic names with Standing in Nomenclature (LPSN), the taxonomic status of the genus Desulforhopalus is: correct name (last update, February 2025) * . LPSN classification: Bacteria / Pseudomonadati / Pseudomonadota / Deltaproteobacteria / Desulfobacterales / Desulfobulbaceae / Desulforhopalus The genus Desulforhopalus can also be recovered in the Genome Taxonomy Database (GTDB) as g__Desulforhopalus (version v220) ** . GTDB classification: d__Bacteria / p__Desulfobacterota / c__Desulfobulbia / o__Desulfobulbales / f__Desulfocapsaceae / g__Desulforhopalus * Meier‐Kolthoff et al. ( 2022 ). Nucleic Acids Res , 50 , D801 – D807 ; DOI: 10.1093/nar/gkab902 ** Parks et al. (
Reaction rates by foil activation (EMC and CFRMF) (1974)

G-protein-coupled receptors represent main targets of several clinically relevant drugs, playing nowadays a leading part for further drug discovery process. Trace amine-associated receptor's family (TAARs) assumed an intriguing role as druggable target in medicinal chemistry, being TAAR1 the most investigated. Indeed, related ligands proved to be intertwined in several circuits involved in pathological pathways or therapeutic routes. Herein, we highlight relevant efforts in the search of novel agonists, focusing on responsiveness featured by different chemotypes toward rodent and human TAAR1, in order to explore species-specificity preferences. We also discuss the main strategies guiding so far the design of new TAAR1 agonists, giving a perspective of the structure-based methodologies aimed at deriving new insights for more potent and selective derivatives.
Separation of fine crackles from vesicular sounds by a nonlinear digital filter (1989)

Crackles are discontinuous adventitious sounds, and their separation is an important process in the analysis of lung sounds. In order to separate the crackles from vesicular sounds automatically, we used a nonlinear digital filter which was designed to separate nonstationary from stationary signals. We applied this filter to the lung sounds recorded from six patients with pulmonary fibrosis. The separation was satisfactory enough to make this method useful in clinical medicine.
Compounds in the pyrrolo[3′,4′:4,5] pyrrolo[3,4‐b]indole series (1978)

Abstract Compounds in the new pyrrolo[3′,4′:4,5]pyrrolo[3,4‐ b ]indole series have been produced by an imide cyclization of appropriate derivatives of pyrrolo[3,4‐ b ]indole.
Use of Sense Marking for Improving WordNet Coverage (2014)

WordNet is a crucial resource that aids in several Natural Language Processing (NLP) tasks.The WordNet development activity for 18 Indian languages has been initiated in INDIA by the IndoWordNet 1 consortium using the expansion approach with the Hindi WordNet developed by IIT Bombay, as the source.After linking 20K synsets, it was decided that each of these languages should find the coverage of their respective language WordNets by using sense marker tool released by IIT Bombay.The sense marking activity mainly helped in validation of WordNet and improving the WordNet coverage.In this paper, the various effects that sense marking activity had on the Konkani 2 language Word-Net development are presented.