gebhart/patrepeval huggingface dataset:
Mouillage à l'échelle nanométrique : effet des forces à longue portée et des hétérogénéités du substrat (2003)

Alors que les phenomenes de mouillage aux petites echelles connaissent un regain d'interet soit theorique soit experimental en vue de nouvelles applications, leur comprehension reste encore limitee. Dans ce contexte, ce travail a porte sur l'etude du mouillage de gouttes d'alcanes de taille nanometrique sur de surfaces modeles realisees par auto-assemblage de monocouches organiques. Cela a demande la mise au point d'une nouvelle technique de Microscopie a Force Atomique (AFM) en mode non-contact permettant d'imager, avec peu d'artefacts, des gouttes de taille variable condensees directement sur des surfaces solides. Nous avons montre ainsi que l'angle de mouillage des alcanes sur des surfaces silanisees, faiblement heterogenes, diminue sensiblement a partir de sa valeur macroscopique lorsque la taille des gouttes devient submicronique. Dans ce systeme, regi par des interactions a longue portee purement dispersives, la tension de ligne est theoriquement trop faible pour etre responsable de l'effet observe. Nous avons donc suppose que les heterogeneites chimiques mesoscopiques du substrat affectent l'angle de mouillage lorsque la taille des gouttes devient suffisamment petite. Ce scenario a ete valide par des simulations numeriques basees sur un modele simplie de la distribution de defauts du substrat. Des experiences similaires, realisees sur des substrats differents (monocouches d'alcanethiols auto-assembles sur or et de chaines alkyles greffees sur silicium), ont aussi mis en evidence l'effet dominant des heterogeneites physico-chimiques faibles du solide sur le mouillage aux petites echelles. Finalement, pour illustrer ulterieurement les potentialites de la technique AFM ici developpee, nous avons etudie le mouillage de surfaces nano-structurees et la mouillabilite locale de la surface du cheveu.
Ca2+activation of myofilaments from transgenic mouse hearts expressing R92Q mutant cardiac troponin T (2001)

The functional consequences of the R92Q mutation in cardiac troponin T (cTnT), linked to familial hypertrophic cardiomyopathy in humans, are not well understood. We have studied steady- and pre-steady-state mechanical activity of detergent-skinned fiber bundles from a transgenic (TG) mouse model in which 67% of the total cTnT in the heart was replaced by the R92Q mutant cTnT. TG fibers were more sensitive to Ca(2+) than nontransgenic (NTG) fibers [negative logarithm of half maximally activating molar Ca(2+) (pCa(50)) = 5.84 +/- 0.01 and 6.12 +/- 0.01 for NTG and TG fibers, respectively]. The shift in pCa(50) caused by increasing the sarcomere length from 1.9 to 2.3 microm was significantly higher for TG than for NTG fibers (DeltapCa(50) = 0.13 +/- 0.01 and 0.29 +/- 0.02 for NTG and TG fibers, respectively). The relationships between rate of ATP consumption and steady-state isometric tension were linear, and the slopes were the same in NTG and TG fibers. Rate of tension redevelopment was more sensitive to Ca(2+) in TG than in NTG fibers (pCa(50) = 5.71 +/- 0.02 and 6.07 +/- 0.02 for NTG and TG fibers, respectively). We concluded that overall cross-bridge cycling kinetics are not altered by the R92Q mutation but that altered troponin-tropomyosin interactions could be responsible for the increase in myofilament Ca(2+) sensitivity in TG myofilaments.
Fabrication of Bentonite–Silica Sand/Suspended Waste Palm Leaf Composite Membrane for Water Purification (2020)

In this study, a method for fabricating tubular ceramic membranes via extrusion using economical and locally available bentonite-silica sand and waste palm leaves was developed as a tool for conducting the necessary task of purifying water polluted with oil and suspended solid materials produced via various industrial processes. The developed tubular ceramic membranes were found to be highly efficient at separating the pollutants from water. The properties of the fabricated membrane were evaluated via mechanical testing, pore size distribution analysis, and contact angle measurements. The water contact angle of the fabricated membrane was determined to be 55.5°, which indicates that the membrane surface is hydrophilic, and the average pore size was found to be 66 nm. The membrane was found to demonstrate excellent corrosion resistance under acidic as well as basic conditions, with weight losses of less than 1% in each case. The membrane surface was found to be negatively charged and it could strongly repulse the negatively charged fine bentonite particles and oil droplets suspended in the water, thereby enabling facile purification through backwashing. The obtained ceramic membranes with desirable hydrophilic properties can thus serve as good candidates for use in ultrafiltration processes.
α1-Proteinase Inhibitor, α1-Antichymotrypsin, and α2-Macroglobulin Are the Antiapoptotic Factors of Vascular Smooth Muscle Cells (2001)

Serum depletion induces cell death. Whereas serum contains growth factors and adhesion molecules that are important for survival, serum is also likely to have antiapoptotic factor(s). We show here that the plasma proteinase inhibitors alpha1-proteinase inhibitor, alpha1-antichymotrypsin, and alpha2-macroglobulin function as critical antiapoptotic factors for human vascular smooth muscle cells. Cell survival was assured when serum-free medium was supplemented with any one or all of the above serine proteinase inhibitors. In contrast, the cells were sensitive to apoptosis when cultured in medium containing serum from which the proteinase inhibitors were removed. The antiapoptotic effect conferred by the proteinase inhibitors was proportional to proteinase inhibitory activity. Without proteinase inhibitors, the extracellular matrix was degraded, and cells could not attach to the matrix. Cell survival was dependent on the intact extracellular matrix. In the presence of the caspase inhibitor z-VAD, the cells detached but did not die. The activity of caspases was elevated without proteinase inhibitors; in contrast, caspases were not activated when medium was supplemented with one of the proteinase inhibitors. In conclusion, the plasma proteinase inhibitors prevent degradation of extracellular matrix by proteinases derived from cells. Presumably an intact cell-matrix interaction inhibits caspase activation and supports cell survival.
Dual pH‐ and thermal‐responsive nanocomposite hydrogels for controllable delivery of hydrophobic drug baicalein (2018)

Abstract Hydrogels have been widely used as mild biomaterials due to their bio‐affinity, high drug loading capability and controllable release profiles. However, hydrogel‐based carriers are greatly limited for the delivery of hydrophobic payloads due to the lack of hydrophobic binding sites. Herein, nano‐liposome micelles were embedded in semi‐interpenetrating poly[( N ‐isopropylacrylamide)‐ co ‐chitosan] (PNIPAAm‐ co ‐CS) and poly[( N ‐isopropylacrylamide)‐ co ‐(sodium alginate)] (PNIPAAm‐ co ‐SA) hydrogels which were responsive to both temperature and pH, thereby establishing tunable nanocomposite hydrogel delivery systems. Nano‐micelles formed via the self‐assembly of phospholipid could serve as the link between hydrophobic drug and hydrophilic hydrogel due to their special amphiphilic structure. The results of transmission and scanning electron microscopies and infrared spectroscopy showed that the porous hydrogels were successfully fabricated and the liposomes encapsulated with baicalein could be well contained in the network. In addition, the experimental results of response release in vitro revealed that the smart hydrogels showed different degree of sensitiveness under different pH and temperature stimuli. The results of the study demonstrate that combining PNIPAAm‐ co ‐SA and PNIPAAm‐ co ‐CS hydrogels with liposomes encapsulated with hydrophobic drugs is a feasible method for hydrophobic drug delivery and have potential application prospects in the medical field. © 2018 Society of Chemical Industry
Setting Up COTS-Based Software Product Lines (2007)

A software product line is a set of software-intensive systems sharing a common, managed set of features that satisfy the specific needs of a particular market segment or mission and are developed from a common set of core assets in a prescribed way (Clements and Northrop, 2001). Many organizations that deal in wide areas of operation, from consumer electronics, telecommunications, and avionics to information technology, are using software product lines practice, because it deals with effective utilization of software assets (Ahmed and Capretz, 2007). Although software product line is gaining popularity due to economical impacts, there has not been a great deal of research in establishing appropriate models for developing software product line from COTS. By having controlled variability and in satisfying the market demands a product line can be built around a set of COTS by analyzing the products to determine the common and variable features
ACCURACY OF CONTINUOUS JUGULAR BULB VENOUS OXIMETRY DURING INTRACRANIAL PROCEDURES (1994)

Gunn, H MD; Matta, B F MB, FRCA; Lam, A M MD, FRCPC; Mayberg, T S MD Author Information
Adrenal Metastasis From Hepatocellular Carcinoma: Radiofrequency Ablation Combined With Adrenal Arterial Chemoembolization in Six Patients (2009)

The combination therapy described is a safe multidisciplinary therapeutic option that can lengthen survival among patients with adrenal metastasis from hepatocellular carcinoma.
AN ENVIRONMENTALLY BENIGN SOYBEAN DERIVED FUEL AS A BLENDING STOCK OR REPLACEMENT FOR HOME HEATING OIL (2001)

The use of bio-derived materials both as fuels and/or as blending stocks becomes more attractive as the price of middle distillate fuels, especially home heating oil, continues to rise. Historically, many biomass and agricultural derived materials have been suggested. One of the most difficult problems encountered with home heating oil is that of storage stability. High maintenance costs associated with home heating oil are, in large part, because of this stability problem. In the present research, Soygold, a soybean derived fuel, was added in concentrations of 10%-20% to both a stable middle distillate fuel and an unstable home heating oil. Fuel instability in this article will be further related to the organo-nitrogen compounds present. The soy-fuel mixtures proved stable, and the addition of the soy liquid enhanced both the combustion properties, and dramatically improved the stability of the unstable home heating oil.
Characterization of underground cellars in the Duero Basin by GNSS, LIDAR and GPR techniques (2013)

The underground cellars of the Duero River basin are part of spread and damaged agricultural landscape which is in danger of disappearing. These architectural complexes are allocated next to small towns. Constructions are mostly dug in the ground with a gallery down or barrel strait through which you access the cave or cellar. This wider space is used to make and store wine. Observation and detection of the winery both on the outside and underground is essential to make an inventory of the rural heritage. Geodetection is a non-invasive technique, suitable to determinate with precision buried structures in the ground. The undertaken works include LIDAR survey techniques, GNSS and GPR obtained data. The results are used to identify with centimetric precision construction elements forming the winery. Graphic and cartographic obtained documents allow optimum visualization of the studied field and can be used in the reconstruction of the place.
Large‐Scale Traveling Atmospheric and Ionospheric Disturbances Observed in GUVI With Multi‐Instrument Validations (2022)

This study presents multi-instrument observations of persistent large-scale traveling ionosphere/atmospheric disturbances (LSTIDs/LSTADs) observed during moderately increased auroral electrojet activity and a sudden stratospheric warming in the polar winter hemisphere. The Global Ultraviolet Imager (GUVI), Gravity field and steady-state Ocean Circulation Explorer, Scanning Doppler Imaging Fabry-Perot Interferometers, and the Poker Flat Incoherent Scatter Radar are used to demonstrate the presence of LSTIDs/LSTADs between 19 UT and 5 UT on 18-19 January 2013 over the Alaska region down to lower midlatitudes. This study showcases the first use of GUVI for the study of LSTADs. These novel GUVI observations demonstrate the potential for the GUVI far ultraviolet emissions to be used for global-scale studies of waves and atmospheric disturbances in the thermosphere, a region lacking in long-term global measurements. These observations typify changes in the radiance from around 140 to 180 km, opening a new window into the behavior of the thermosphere.
Prolog for Programmers (1985)

This book is an introduction to PROLOG, its use and implementation, assumes the reader has some programming experience and relates the unconventional PROLOG constructs to the programming methods and techniques used in, say, PASCAL, thus helping to cross the psychological barrier between the two approaches. The book is practically oriented but avoids irritating the more sophisticated reader with the boring repetitions of obvious, elementary methods and procedures found in many introductory level texts. The version of PROLOG used is almost identical to the widely accepted Edinburgh PROLOG (the few differences are documented). The book includes: an introduction to PROLOG; programming techniques in PROLOG; the principles of implementing PROLOG systems; a description of a PROLOG interpreter for small computers (written in PASCAL and PROLOG) with complete listings; two case studies in PROLOG applications (a planning program by D.H.D. Warren and an implementation of Sequel-like database query language) with complete listings; a short overview of some important PROLOG dialects.
Clinical Trials Update from the American College of Cardiology Meeting: CARE-HF and the Remission of Heart Failure, Women’s Health Study, TNT, COMPASS-HF, VERITAS, CANPAP, PEECH and PREMIER (2005)

This article provides information and a commentary on landmark trials presented at the American College of Cardiology meeting held in March 2005, relevant to the pathophysiology, prevention and treatment of heart failure. All reports should be considered as preliminary data, as analyses may change in the final publication. CARE-HF showed that Cardiac Re-synchronisation Therapy, administered in addition to expert pharmacological management, reduced all cause mortality and CV hospitalisation in patients with moderate or severe heart failure and cardiac dyssynchrony. The Women's Health Study showed no benefit of vitamin E supplementation or aspirin in the primary prevention of CV disease. The TNT study showed that reducing LDL cholesterol to levels lower than currently recommended, produced a 22% reduction in the incidence of major cardiovascular events. In COMPASS, an implantable device that continuously monitors intra-cardiac pressures was shown to be safe and to improve care in patients with chronic heart failure. Tezosentan failed to show benefit in patients with acute heart failure in the VERITAS study. The CANPAP study failed to show a benefit of continuous positive airway pressure on mortality and heart transplantation in heart failure patients with central sleep apnoea. EECP therapy improved exercise capacity but had no effect on peak VO2 in heart failure patients in the PEECH study. In the PREMIER study the matrix metalloproteinase inhibitor PG-116800 failed to prevent LV remodelling following myocardial infarction.
Rendezvous Protocols and Dynamic Frequency Hopping Interference Design for Anti-Jamming Satellite Communication (2013)

Abstract : Cognitive radio technology combines high re-configurability with intelligent spectrum management and adaptation, which materializes into a highly agile and spectrally efficient platform for communications. In fact, cognitive radio technology enables the use of opportunistic spectrum access of the underutilized portions of the assigned spectrum. The benefit of such technology and capabilities for military satellite communications is not well understood. This project studies the properties of new algorithms for frequency hopping, a key component in cognitive radio technology. Methods from game theory and hybrid systems theory are employed for the analytical study, while computer simulations are used to validate these findings.
Amyloids: From molecular structure to mechanical properties (2013)

Many proteins of diverse sequence, structure and function self-assemble into morphologically similar fibrillar aggregates known as amyloids. Amyloids are remarkable polymers in several respects. First of all, amyloids can be formed from proteins with very different amino acid sequences; the common denominator is that the individual proteins constituting the amyloid fold predominantly into a β-sheet structure. Secondly, the formation of the fibril occurs through non-covalent interactions between primarily the β-sheets, causing the monomers to stack into fibrils. The fibrils are remarkably robust, considering that the monomers are bound non-covalently. Finally, a common characteristic of fibrils is their unbranched, straight, fiber-like structure arising from the intertwining of the multiple β-sheet filaments. These remarkably ordered and stable nanofibrils can be useful as building blocks for protein-based functional materials, but they are also implicated in severe neurodegenerative diseases. The overall aim of this article is to highlight recent efforts aimed at obtaining insights into amyloid proteins on different length scales. Starting from molecular information on amyloids, single fibril properties and mechanical properties of networks of fibrils are described. Specifically, we focus on the self-assembly of amyloid protein fibrils composed of peptides and denatured model proteins, as well as the influence of inhibitors of fibril formation. Additionally, we will demonstrate how the application of recently developed vibrational spectroscopic techniques has emerged as a powerful approach to gain spatially resolved information on the structure–function relation of amyloids. While spectroscopy provides information on local molecular conformations and protein secondary structure, information on the single fibril level has been developed by diverse microscopic techniques. The approaches to reveal basic mechanical properties of single fibrils like bending rigidity, shear modulus, ultimate tensile strength and fracture behavior are illustrated. Lastly, mechanics of networks of amyloid fibrils, typically forming viscoelastic gels are outlined, with a focus on (micro-) rheological properties. The resulting fundamental insights are essential for the rational design of novel edible and biodegradable protein-based polymers, but also to devise therapeutic strategies to combat amyloid assembly and accumulation during pathogenic disorders.
The Fractal Geometry of Nature. (1984)

...a blend of erudition (fascinating and sometimes obscure historical minutiae abound), popularization (mathematical rigor is relegated to appendices) and exposition (the reader need have little knowledge of the fields involved) ...and the illustrations include many superb examples of computer graphics that are works of art in their own right. Nature
Highly Conductive, Flexible, Polyurethane‐Based Adhesives for Flexible and Printed Electronics (2012)

Abstract Flexible interconnects are one of the key elements in realizing next‐generation flexible electronics. While wire bonding interconnection materials are being deployed and discussed widely, adhesives to support flip‐chip and surface‐mount interconnections are less commonly used and reported. A polyurethane (PU)‐based electrically conductive adhesive (ECA) is developed to meet all the requirements of flexible interconnects, including an ultralow bulk resistivity of ≈1.0 × 10 −5 Ω cm that is maintained during bending, rolling, and compressing, good adhesion to various flexible substrates, and facile processing. The PU‐ECA enables various interconnection techniques in flexible and printed electronics: it can serve as a die‐attach material for flip‐chip, as vertical interconnect access (VIA)‐filling and polymer bump materials for 3D integration, and as a conductive paste for wearable radio‐frequency devices.
Differentiation of Clover Rhizobium Isolated from Biosolids‐Amended Soils with Varying pH (1997)

Abstract Metal contamination may alter the diversity of microbes residing in soil. The genetic structure and phenotypic characteristics of clover Rhizobium isolated from contaminated and control soils were compared. Plant infection and symbiotic competence tests were used for phenotypic characterization. Variation across isolates in fingerprint patterns determined with primers for repetitive extragenic palindromic (REP) sequences and the polymerase chain reaction (PCR) were used for genetic characterization. Two phenotypic groups of effective and ineffective isolates were identified using the symbiotic effectiveness test. Soil pH was the primary factor influencing this phenotypic characteristic. Effective isolates were associated with higher soil pH and ineffective isolates were associated with lower soil pH regardless of soil metal content. The isolates were genetically diverse. The variation of isolates from the different soils overlapped, indicating that neither the heavy metals nor the low soil pH resulted in the selection of a single genotype. Isolates from the most heavily contaminated soils were more variable than isolates from control soils. Soil pH, and not heavy metal content, was important in the selection of rhizobia that formed ineffective N 2 ‐fixing symbioses.
<title>An on-the-ground simulator of autonomous docking and spacecraft servicing for research and education</title> (2004)

On-orbit spacecraft servicing has become a realistic and promising space mission. The Autonomous Docking and Spacecraft Servicing Simulator (AUDASS), introduced in this paper, is a research facility for on-the-ground testing of proximity navigation, docking and satellite servicing technologies and for the experimental verification of dynamics models and control laws. Moreover, the test-bed constitutes a valuable educational tool for the university students directly involved in its design and exploitation. This paper presents the current status of the on-going development of the AUDASS simulator and reports the results of some preliminary tests. The AUDASS system consists of two independent robotic vehicles, a chaser and a target. The vehicles float, via air pads, on a polished granite table providing a frictionless support for the simulation in 2-D of the micro-gravity dynamics. The introduction of the paper provides a wide overview of the on-going research efforts to make autonomous docking and servicing of spacecraft a reality.