gebhart/patrepeval huggingface dataset:
The Enterprise model for developing distributed applications (1993)

Enterprise is a programming environment for designing, coding, debugging, testing, monitoring, profiling, and executing programs for distributed hardware. Developers using Enterprise do not deal with low-level programming details such as marshalling data, sending/receiving messages, and synchronization. Instead, they write their programs in C, augmented by new semantics that allow procedure calls to be executed in parallel. Enterprise automatically inserts the necessary code for communication and synchronization. However, Enterprise does not choose the type of parallelism to apply. The developer is often the best judge of how parallelism can be exploited in a particular application, so Enterprise lets the programmer draw a diagram of the parallelism using a familiar analogy that is inherently parallel: a business organization, or enterprise, which divides large tasks into smaller tasks and allocates assets to perform those tasks. These assets correspond to techniques used in most large-grained parallel programs; pipelines, master/slave processes, divide-and-conquer, and so on,and the number and kinds of assets used determine the amount of parallelism.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Anti-human immunodeficiency virus effects of dextran sulfate are strain dependent and synergistic or antagonistic when dextran sulfate is given in combination with dideoxynucleosides (1990)

The effects of three molecular weight ranges of dextran sulfate on five different human immunodeficiency virus (HIV) isolates (from patients with acquired immunodeficiency syndrome), alone and in combination with dideoxynucleosides, were investigated in vitro. The higher the molecular weight range of dextran sulfate, the more potent the activity as assessed by a quantitative syncytium formation assay. Although all five HIV isolates had similar susceptibilities to the inhibitory effects of dideoxynucleosides, the two clinical isolates of HIV (HIV type 1 [HIV-1] TM and SP) exhibited a pattern of reduced susceptibility to dextran sulfate when compared with the two cloned isolates (HIV-1 WMF and HIV-2 ROD) and a prototype laboratory strain (HIV-1 IIIB). In combination with dideoxynucleosides, the high-molecular-weight range of dextran sulfate (500,000) resulted in an antagonistic response directed against the two clinical isolates of HIV (HIV-1 TM and SP) when the antiviral concentrations of dextran sulfate were in the ineffective range. Additive or synergistic effects were seen with the other three HIV isolates and all five HIV isolates when the low-molecular-weight range of dextran sulfate (8,000) was used. The results of these studies raise issues on the impact of drug-resistant strains on disease progression and the use of dextran sulfate in combination with nucleoside analogs for the clinical management of HIV disease.
Monitoring of binder removal from injection molded ceramics using air-coupled ultrasound at high temperature (1999)

A pair of capacitance-type air-coupled ultrasonic transducers have been constructed that were capable of operating in air at temperatures of 500 to 600 degrees C. These devices were then used to monitor the pyrolytic removal of organic binder from injection molded silicon nitride ceramic components using air-coupled ultrasound inside a furnace at elevated temperatures. Through-thickness waveforms were obtained in the ceramic and compared with simultaneous measurements of the mass of the sample. Both the ultrasonic velocity and signal amplitudes could be used to monitor the change in mass of the injection molded ceramic, and other phenomena (such as softening and redistribution of the binder) were observed.
Postnatal Changes in the Aorta of Howler Monkeys (Alouatta Caraya) (1966)

Journal Article Postnatal Changes in the Aorta of Howler Monkeys (Alouatta Caraya) Get access Cesar A. Maruffo, M.D., Cesar A. Maruffo, M.D. Search for other works by this author on: Oxford Academic PubMed Google Scholar Manuel R. Malinow, M.D. Manuel R. Malinow, M.D. 2Oregon Regional Primate Research CenterBeaverton, Oregon Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Gerontology, Volume 21, Issue 1, January 1966, Pages 119–123, https://doi.org/10.1093/geronj/21.1.119 Published: 01 January 1966
Accelerating Science Impact through Big Data Workflow Management and Supercomputing (2016)

The Large Hadron Collider (LHC), operating at the international CERN Laboratory in Geneva, Switzerland, is leading Big Data driven scientific explorations. ATLAS, one of the largest collaborations ever assembled in the the history of science, is at the forefront of research at the LHC. To address an unprecedented multi-petabyte data processing challenge, the ATLAS experiment is relying on a heterogeneous distributed computational infrastructure. To manage the workflow for all data processing on hundreds of data centers the PanDA (Production and Distributed Analysis)Workload Management System is used. An ambitious program to expand PanDA to all available computing resources, including opportunistic use of commercial and academic clouds and Leadership Computing Facilities (LCF), is realizing within BigPanDA and megaPanDA projects. These projects are now exploring how PanDA might be used for managing computing jobs that run on supercomputers including OLCF’s Titan and NRC-KI HPC2. The main idea is to reuse, as much as possible, existing components of the PanDA system that are already deployed on the LHC Grid for analysis of physics data. The next generation of PanDA will allow many data-intensive sciences employing a variety of computing platforms to benefit from ATLAS experience and proven tools in highly scalable processing.
A 2w, 4 GHz GaAsFET Amplifier for Radio Relay Applications (2005)

A 2W, 4 GHz GaAsFET amplifier has been developed with performance suitable for replacement of the close-spaced triode transmitter amplifier in the 4 GHz radio relay systems (TD-2 and TD-3D). The amplifier produces a minimum of 21dB of gain using three stages, with a single GaAsFET in each stage.
A Coalescent Model of Ancestry for a Rare Allele (2000)

In disequilibrium mapping from data on a rare allele, interest may focus on the ancestry of a random sample of current descendants of a mutation. The mutation is assumed to have been introduced into the population as a single copy a known time ago and to have reached a given copy number within the population. Theory has been developed to describe the ancestral distribution under arbitrary patterns of population expansion. Further results permit convenient realization of the ancestry for a random sample of copies of a rare allele within populations of constant size or within populations growing or shrinking at constant exponential rate. In this article, we present an efficient approximate method for realizing coalescence times under more general patterns of population growth. We also apply diagnostics, checking the age of the mutation. In the course of the derivation, some additional insight is gained into the dynamics of the descendants of the mutation.
ON MIRANDESE LANGUAGE RESOURCES FOR TEXT-TO-SPEECH (2014)

This paper aims at describing the major components of the first Text-to-Speech (TTS) system ever built for Mirandese, [1] a minority language spoken in the Northeast of Portugal. Both language resources development (corpus, textnormalization rules, annotated lexicon, phone sets and recordings) and the TTS (Statistical Parameter Synthesis) system are documented here.
SITE SELECTION PLAN AND INSTALLATION GUIDELINES FOR A NATIONWIDE DIFFERENTIAL GPS SERVICE (1997)

This document focuses on the concept, configuration,operation, and performance of a nationwide differential Global Positioning System (DGPS) service. It presents the general requirement for DGPS broadcast site selection, and the recommended locations of broadcast sites. The object is to complete nationwide coverage of the DGPS correction signal. The document also describes the equipment that is required for broadcast site operations as well as the basic operation of the equipment.
Acoustic Source Localization Using Time Delay Estimation (2007)

The angular location of an acoustic source can be estimated by measuring an acoustic direction of incidence based solely on the noise produced by the source. Methods for determining the direction of incidence based on sound intensity, the phase of cross-spectral functions, and cross-correlation functions are available. In this current work, we implement Dominant Frequency SElection (DFSE) algorithm. Direction of arrival (DOA) estimation usingmicrophone arrays is to use the phase information present in signals from microphones that are spatially separated. DFSE uses the phase diﬀerence between the Fourier transformedsignals to estimate the direction ofarrival (DOA)and is implemented using a three-element ’L’ shaped microphone array, linear microphone array, and planar 16-microphone array. This method is based on simply locating the maximum amplitude from each of the Fourier transformed signals and thereby deriving the source location by solving the set of non-linear least squares equations. For any pair of microphones, the surface on whichthe time diﬀerence ofarrival (TDOA) is constant is a hyperboloidoftwo sheets. Acoustic source localization algorithms typically exploit this fact by grouping all microphones into pairs, estimating the TDOA of each pair, then ﬁnding the point where all associated hyperboloids most nearly intersect. We make use of both closed-form solutions and iterative techniques to solve for the source location.Acoustic source positioned in 2-dimensional plane and 3-dimensional space have been successfully located.
The pressure dependence of tunnelling of coupled pairs of methyl groups in lithium acetate dihydrate (1992)

The pressure dependence of tunnelling of coupled pairs of methyl groups in lithium acetate dihydrate has been investigate using the neutron scattering spectrometer IRSIS. Methyl tunnelling spectra recorded at a temperature of 5 K and pressures up to 9.5 kbar, reveal structure which has been attributed to coupling. The data, which extend an earlier investigation by Heidemann et al. (1987) have been fitted to a time-independent Hamiltonian, and the fit parameters include the potential barriers of the individual methyl groups and the coupling potential between them. The magnitudes of both parameters increase with increasing pressure and their pressure dependence has been analyzed to provide information on the inter-molecular forces.
Mitochondrial Damage Mediates Genotoxicity of Arsenic in Mammalian Cells (2005)

Arsenic is an important environmental carcinogen that affects millions of people worldwide through contaminated water supplies. For decades, arsenic was considered a nongenotoxic carcinogen. Using the highly sensitive A(L) mutation assay, we previously showed that arsenic is, indeed, a potent gene and chromosomal mutagen and that its effects are mediated through the induction of reactive oxygen species. However, the origin of these radicals and the pathways involved are not known. Here we show that mitochondrial damage plays a crucial role in arsenic mutagenicity. Treatment of enucleated cells with arsenic followed by rescue fusion with karyoplasts from controls resulted in significant mutant induction. In contrast, treatment of mitochondrial DNA-depleted (rho(0)) cells produced few or no mutations. Mitochondrial damage can lead to the release of superoxide anions, which then react with nitric oxide to produce the highly reactive peroxynitrites. The mutagenic damage was dampened by the nitric oxide synthase inhibitor, N(G)-methyl-L-arginine. These data illustrate that mitochondria are a primary target in arsenic-induced genotoxic response and that a better understanding of the mutagenic/carcinogenic mechanism of arsenic should provide a basis for better interventional approach in both treatment and prevention of arsenic-induced cancer.
A very long chain fatty acid responsive transcription factor, MYB93 , regulates lateral root development in Arabidopsis (2023)

Lateral roots (LRs) are critical to root system architecture development in plants. Although the molecular mechanisms by which auxin regulates LR development have been extensively studied, several additional regulatory systems are hypothesized to be involved. Recently, the regulatory role of very long chain fatty acids (VLCFAs) has been shown in LR development. Our analysis showed that LTPG1 and LTPG2, transporters of VLCFAs, are specifically expressed in the developing LR primordium (LRP), while the number of LRs is reduced in the ltpg1/ltpg2 double mutant. Moreover, late LRP development was hindered when the VLCFA levels were reduced by the VLCFA synthesis enzyme mutant, kcs1-5. However, the details of the regulatory mechanisms of LR development controlled by VLCFAs remain unknown. In this study, we propose a novel method to analyze the LRP development stages with high temporal resolution using a deep neural network and identify a VLCFA-responsive transcription factor, MYB93, via transcriptome analysis of kcs1-5. MYB93 showed a carbon chain length-specific expression response following treatment of VLCFAs. Furthermore, myb93 transcriptome analysis suggested that MYB93 regulated the expression of cell wall organization genes. In addition, we also found that LTPG1 and LTPG2 are involved in LR development through the formation of root cap cuticle, which is different from transcriptional regulation by VLCFAs. Our results suggest that VLCFA is a regulator of LRP development through transcription factor-mediated regulation of gene expression and the transportation of VLCFAs is also involved in LR development through root cap cuticle formation.
Development of an I/M Short Emissions Test for Buses (1992)

&lt;div class="htmlview paragraph"&gt;Emissions from existing diesel-powered urban buses are increasingly scrutinized as local, state, and federal governments require enforcement of more stringent emission regulations and expectations. Currently, visual observation of high smoke levels from diesel-powered equipment is a popular indicator of potential emission problems requiring tune-up or engine maintenance. It is important that bus inspection and maintenance (I/M) operations have a quality control “test” to check engine emissions or diagnose the engine state-of-tune before or after maintenance. Ideally, the “emission test” would be correlated to EPA transient emissions standards, be of short duration, and be compatible with garage procedures and equipment.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;In support of developing a useful “short-test,” equipment was designed to collect samples of raw exhaust over a short time period for gaseous and particulate emissions. These samples are collected over two short test cycles using 30-second sampling intervals, while the bus engine is operated in a specified manner with the brakes locked and transmission in “Drive.” Concentrations of CO, NO&lt;sub&gt;x&lt;/sub&gt;, and O&lt;sub&gt;2&lt;/sub&gt; are determined using a portable emissions analyzer. Particulate concentrations or smoke levels are assessed by reading the light reflectance of the sample filter (this filter may also be weighed for quantitative determinations). Ideally, “short-test emission factors” can be used to estimate EPA transient cycle emissions of CO, NO&lt;sub&gt;x&lt;/sub&gt;, and particulate as derived for a 1986 DDC 6V92-TA in this work. Additional correlation work to include other engine families is dependent on continued industry interest.&lt;/div&gt;
Design of non-cytotoxic 6,7-dihydroxycoumarin-5-carboxylates with antibiofilm activity against Staphylococcus aureus and Candida albicans (2023)

The 6,7-dihydroxycoumarin-5-carboxylates DHCou and 4-Me-DHCou have been synthesized <i>via</i> five-step route including a propargyl-Claisen rearrangement as key step. The compounds show antibiofilm activity against <i>Stapylococcus aureus</i> and <i>Candida albicans</i> but lack the cytotoxic activity of parent 6,7-dihydroxycoumarines such as esculetin and 4-methylesculetin.
Multiagent Architecture Combined with a Multicontract Protocol for FMS Control (2001)

This paper describes a new Multiagent architecture for control of flexible manufacturing. In this architecture, agents coordinate their actions following a new negotiation protocol used for scheduling and rescheduling of tasks. The proposed protocol, MultiContract-Net, is an innovation of Contract-Net protocol enabling several tasks to be negotiated concurrently in real time with optimal results. Thus, the multicontract-Net protocol enables both dynamic task allocation and optimization of opportunities provided by manufacturing flexibility by handling knowledge uncertainty characterizing the negotiation process. This paper stresses the efficiency of distributed implementation.
Polysomnography in obese children with a history of sleep‐associated breathing disorders (1993)

We hypothesized that obese children with a history of breathing difficulty during sleep would demonstrate (1) evidence of complete and partial obstructive sleep apnea (OSA) with hypercarbia and/or hypoxemia; and (2) correlation between symptoms, degree of obesity, adenoid and tonsil size, and polysomnography (PSG) results. We evaluated 32 obese children [% ideal body weight (IBW), 196 +/- 45%] with a sleep history questionnaire, airway radiographs, electrocardiograms (ECG), and PSG. By history, we found snoring (100%), difficulty breathing (59%), sweating (44%), restlessness (53%), arousals (41%), apnea (50%), worsening with upper respiratory infection (URI) (81%), hypersomnolence (59%), and mouth breathing (59%). We found adenoid and/or tonsil enlargement on 75% of airway x-ray pictures. ECGs were abnormal in 5 patients. Among all patients, mean sleep study oxyhemoglobin saturation (SaO2) was 85 +/- 16% and mean end-tidal CO2 (PetCO2) was 51 +/- 7 torr; 84% had paradoxical inward movement of the chest on inspiration, 59% had OSA, and 66% had partial OSA. In those with > or = 200% IBW and adenotonsillar enlargement, elevated PetCO2 and the presence of hypoxemia (SaO2 < 90%) for > or = 5% of the total sleep time (TST) were correlated, unlike in patients of similar weight but without adenotonsillar enlargement. Individuals symptoms did not correlate with the severity of PSG abnormalities. By discriminant analysis, using three variables (IBW, presence of adenotonsillar tissue, and presence of > or = 5 symptoms), we could predict PSG abnormalities with up to 81% reliability. Our findings indicate that in obese children, particularly those with %IBW > or = 200 and adenotonsillar hypertrophy, with sleep-disordered breathing evaluation by polysomnography should be considered.
89Zr-Labeled Dextran Nanoparticles Allow in Vivo Macrophage Imaging (2011)

Tissue macrophages play a critical role both in normal physiology and in disease states. However, because of a lack of specific imaging agents, we continue to have a poor understanding of their absolute numbers, flux rates, and functional states in different tissues. Here, we describe a new macrophage specific positron emission tomography imaging agent, labeled with zirconium-89 ((89)Zr), that was based on a cross-linked, short chain dextran nanoparticle (13 nm). Following systemic administration, the particle demonstrated a vascular half-life of 3.9 h and was found to be located primarily in tissue resident macrophages rather than other white blood cells. Subsequent imaging of the probe using a xenograft mouse model of cancer allowed for quantitation of tumor-associated macrophage numbers, which are of major interest in emerging molecular targeting strategies. It is likely that the material described, which allows the visualization of macrophage biology in vivo, will likewise be useful for a multitude of human applications.
Tissue pulsatility imaging: Ultrasonic measurement of strain due to perfusion (2006)

Over each cardiac cycle perfused tissues expand and relax by a fraction of a percent as blood rapidly accumulates in the arterial vasculature during systole and then slowly drains through the venous vasculature during diastole. Tissue pulsatility imaging (TPI) is a variation on ultrasonic tissue strain imaging that estimates tissue perfusion from this natural, cyclic tissue expansion and relaxation. TPI is derived in principle from plethysmography, a century-old technology for measuring gross tissue volume change from a whole limb or other isolatable body part. With TPI, the plethysmographic signal is measured from hundreds or thousands of sample volumes within an ultrasound image plane to characterize the local perfusion throughout a body part. TPI measures tissue strain over the cardiac cycle and parametrizes the signal in terms of its amplitude and shape. The amplitude of the strain waveform is correlated with perfusion, and the shape of the waveform is correlated with vascular resistance. Results will be presented from the leg showing the change in the TPI signals as the muscles recover from exercise, from breast tumors, and from the brain as blood flow changes in response to visual stimulation. [Work supported in part by NIH 1-R01EB002198-01 and NIH N01-CO-07118.]
Selective Laser Sintering 3D Printing of Orally Disintegrating Printlets Containing Ondansetron (2020)

The aim of this work was to explore the feasibility of using selective laser sintering (SLS) 3D printing (3DP) to fabricate orodispersable printlets (ODPs) containing ondansetron. Ondansetron was first incorporated into drug-cyclodextrin complexes and then combined with the filler mannitol. Two 3D printed formulations with different levels of mannitol were prepared and tested, and a commercial ondansetron orally disintegrating tablet (ODT) product (Vonau<sup>®</sup> Flash) was also investigated for comparison. Both 3D printed formulations disintegrated at ~15 s and released more than 90% of the drug within 5 min independent of the mannitol content; these results were comparable to those obtained with the commercial product. This work demonstrates the potential of SLS 3DP to fabricate orodispersible printlets with characteristics similar to a commercial ODT, but with the added benefit of using a manufacturing technology able to prepare medicines individualized to the patient.
A miniaturized long-life acoustic transmitter for animal tracking in marine environments (2020)

Marine and hydrokinetic (MHK) energy devices are early-stage technologies and their impacts to ocean life and environment are largely unknown, which consequently limits the progress of deploying these devices at commercial scale. Optical and acoustic imaging have been the primary technologies for monitoring marine animals' behavior at existing or potential MHK sites. However, these technologies lack the ability to identify individual animals, which makes them less useful in identifying protected species as well as studying the animals' long-term behavior. Implantable acoustic transmitters with unique identification codes could be used as a complementary technology. To minimize effects of transmitter implantation on the tagged animals and study them for longer durations, it is desired that the implanted transmitter be as small and light as possible and can last for as long as possible. To date, the smallest acoustic transmitters suitable for marine animal tracking have relatively short service life and detection range (up to 200 m), In this report, we introduce a new miniaturized acoustic transmitter which operates at 208.3 kHz. It offers a smaller dry weight (0.45 g), a significantly longer service life (140 days at a 5-second ping rate) as well as a greater detection range than the existing commercial counterparts, which will help obtain more comprehensive movement and behavioral information of animals around MHK energy devices.
Obituary : J.L.Styan 1923 - 2002 (2003)

I f you want to get to know Shakespeare, the last thing you want is to hear a lecture about him. If someone is hungry, you do not thrust a cookbook into his hands and say, 'Read page 20; you'll love the part about roast beef and baked potato'.