gebhart/patrepeval huggingface dataset:
Watermelon mosaic virus reported for the first time in Poland (2009)

Watermelon mosaic virus (WMV) is a member of the genus Potyvirus (family Potyviridae) and consists of flexuous, filamentous particles, approximately 750 nm long. The virus can cause economically important diseases in several horticultural crops, mostly cucurbits and legumes, resulting in quality and yield losses. WMV can experimentally infect more than 170 plant species belonging to 27 families, including many weeds that can host the virus between crops. The geographical occurrence of the virus is patchy and depends on climatic conditions. So far in Europe it has been only detected in southern countries, i.e. Croatia, France, Italy and Slovakia (Desbiez et al., 2007). In 2008, fifteen samples of zucchini plants with mosaic symptoms on the leaves were collected from three fields in Poland. All samples were analyzed by DAS-ELISA with commercial antisera for the detection of WMV, Zucchini yellow mosaic virus (ZYMV) and Papaya ringspot virus (PRSV) (DSMZ, Braunschweig, Germany). WMV was found in every sample tested. There were no positive reactions using antisera to ZYMV and PRSV. WMV in samples testing positive by ELISA was confirmed by RT-PCR. Total RNA was extracted by a phenol-chloroform method from fresh, infected zucchini leaves. RNA samples were tested for the presence of WMV using specific primers designed to amplify a fragment of the coat protein gene (Sharifi et al., 2008). PCR products were cloned into the pGEM-T Easy Vector (Promega) and sequenced. Sequences were compared to data available in GenBank. An 822-nt amplicon was obtained (GenBank Accession No. FJ628395). This had 98% nt sequence identity with WMV sequences from China and Korea (EF127832 and AB369278, respectively) and only 93% nucleotide sequence identity with WMV sequences from France and Pakistan (AY437609 and AB127934, respectively) (Desbiez & Lecoq, 2008). This is the first report of the natural occurrence of WMV in Poland.
Photoinduced energy transfer between water-soluble CdTe quantum dots and aluminium tetrasulfonated phthalocyanine (2007)

Thiol stabilized CdTe quantum dots (QDs) synthesized in aqueous phase were used as energy donors to aluminium tetrasulfonated phthalocyanine (AlTSPc) through fluorescence resonance energy transfer (FRET). Energy transfer occurred from the QDs to AlTSPc upon photoexcitation of the QDs. An enhancement in efficiency of energy transfer with the nature of the carboxylic thiol stabilizers on the QDs was observed. The results showed that for enhanced FRET to occur, the donor–acceptor distance has to be lower than the critical distance. The quenching constant K as well as the binding constant kb values were calculated suggesting strong interaction of the QDs with the AlTSPc. Study of the photophysics of AlTSPc in the presence of the QDs revealed a high triplet state yield, hence the possibility of using QDs in combination with phthalocyanines as photosensitizers in photodynamic therapy. The triplet state lifetimes of AlTSPc in the presence of the QDs were calculated and the lifetime in the presence of CdTe capped with 3-mercaptopropionic acid (MPA) was found to be the longest. MPA capped QD in a mixture with AlTSPc resulted in long triplet lifetime and high triplet yield of the latter, and high energy transfer efficiency, hence was found to be most suitable as a potential candidate for photodynamic therapy of cancer studies.
Stability analysis on the DC Power Distribution System of More Electric Aircraft (2008)

The local DC power distribution system (PDS) of a more electric aircraft is one of the cores of the electric power transmission. Generally, the PDS is made up of small power subsystems designed on their own stand-alone operation. But the interaction between the subsystems (sources and loads) induces some problems of stability. This paper compares the different stability behaviours of two load models: resistive load and constant power load. Some tests for the two load models at different operating points are carried out and the results are compared. The small signal theory and the impedance criterion GMPM (gain margin phase margin) are used to analyse the stability of each system. At conclusion, some statements are expressed to contribute to such electric interconnected systems stability.
Phase-Equilibrium Properties of System Carbon Dioxide-Hydrogen Sulfide (1953)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhase-Equilibrium Properties of System Carbon Dioxide-Hydrogen SulfideJames A. Bierlein and Webster B. KayCite this: Ind. Eng. Chem. 1953, 45, 3, 618–624Publication Date (Print):March 1, 1953Publication History Published online1 May 2002Published inissue 1 March 1953https://pubs.acs.org/doi/10.1021/ie50519a043https://doi.org/10.1021/ie50519a043research-articleACS PublicationsRequest reuse permissionsArticle Views789Altmetric-Citations121LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Transport properties of carrier-injected DNA (2003)

We have studied electric properties of carrier-injected deoxyribonucleic acid (DNA) molecules. First, a current (ICA) through a single DNA molecule was measured by the two-probe dc method with varying a distance between a cathode and an anode (dCA). The ICA–dCA curve showed that the current rapidly decreased with increasing dCA (ICA≲0.1 nA for dCA≳6 nm) according to a hopping model. Next, we measured electric properties of DNA injected carriers by two methods; a field effect transistor (FET) arrangement and a chemical doping. In the FET arrangement, we set three electrodes on a single DNA molecule as source, drain, and gate electrodes with a source–drain distance (dDS)∼20 nm. When a voltage was applied to the gate, the source–drain current (IDS) could be detected to be 0.5–2 nA. This showed that charge injection with the FET arrangement would yield a carrier transportation through DNA at least dDS∼20 nm. In order to flow a current through DNA over a distance ∼100 μm, we synthesized the DNA-acceptor cross-linked derivatives (DACD). In the structure of DACD, DNA molecules, which were attached acceptor molecules at guanine sites specifically, were cross-linked by linker molecules. We can modulate the carrier concentration in DACD with changing a guanine–cytosine pair content (pGC) in a DNA double strand. We measured the current–voltage curves of DACD for various pGC. The conductivity of DACD increased nonlinearly with an increase in pGC. We explained this behavior using a percolation model, so that a two-dimensional conductive network would form in DACD.
A patient-specific algorithm for the detection of seizure onset in long-term EEG monitoring: possible use as a warning device (1997)

During long-term electroencephalogram (EEG) monitoring of epileptic patients, a seizure warning system would allow patients and observers to take appropriate precautions. It would also allow observers to interact with patients early during the seizure, thus revealing clinically useful information. We designed patient-specific classifiers to detect seizure onsets. After a seizure and some nonseizure data are recorded in a patient, they are used to train a classifier. In subsequent monitoring sessions, EEG patterns have to pass this classifier to determine if a seizure onset occurs. If it does, an alarm is triggered. Extreme care has been taken to ensure a low false-alarm rate, since a high false-alarm rate would render the system ineffective. Features were extracted from the time and frequency domains and a modified nearest-neighbor (NN) classifier was used. The system reached an onset detection rate of 100% with an average delay of 9.35 a after onset. The average false-alarm rate was only 0.02/h. The method was evaluated in 12 patients with a total of 47 seizures. Results indicate that the system is effective and reasonably reliable. Computation load has been kept to a minimum so that real-time processing is possible.
Inside Cover: Room Temperature Magnetic Detection of Spin Switching in Nanosized Spin‐Crossover Materials (Angew. Chem. Int. Ed. 4/2013) (2013)

Spin transitions in nanosized materials can be detected using a highly sensitive hybrid sensor, which combines anisotropic magnetoresistive and planar Hall effects. In their Communication on page 1185 ff., F. Terki, C. G. Kim, A. Bousseksou, and co-workers describe a prototype of the sensor and discuss its use for nanoscale magnetic measurements around room temperature. The picture shows an artistic view of the sensor, on which nanoparticles of a ferrous spin-crossover complex have been deposited.
Epidermal growth factor accelerates renal tissue repair in a model of gentamicin nephrotoxicity in rats (1992)

Epidermal growth factor (EGF) is a potent mitogen for renal tubular cells that possess specific high-affinity binding sites for this polypeptide. However, actual function of EGF within the kidney remains to be elucidated. We evaluated the effect of exogenous EGF administration on the rate of tubular regeneration in an experimental model of gentamicin (GT) nephrotoxicity. Female Sprague-Dawley rats were anesthetized, and a miniosmotic pump filled with mouse EGF or saline was implanted subcutaneously. Twenty-four hours later, GT (40 mg.kg-1 x 12 h-1 ip) was given for 4 and 8 days. Groups of treated animals and controls were killed either the day after cessation of treatment (days 5 and 9) or 4 and 8 days after the end of 8-day GT administration (days 12 and 16). Cortical GT levels of groups killed at days 5, 9, 12, and 16 were similar in animals infused with saline or EGF. Serum creatinine levels were significantly higher in GT-treated animals infused with EGF or saline and killed at days 9 and 12 compared with saline-treated animals infused with EGF or saline alone (P < 0.01). Blood urea nitrogen (BUN) also increased as a result of GT administration. However, in animals receiving GT and EGF and killed at day 16, mean BUN level was significantly lower (P < 0.01) compared with rats dosed with GT alone. In treated rats, the extent of tubular regeneration, evaluated by the rate of [3H]thymidine incorporation into renal cortical DNA or by the frequency of S-phase cells (histoautoradiography), was increased in a dose- and time-dependent fashion.(ABSTRACT TRUNCATED AT 250 WORDS)
Image quality improvement in Fresnel zone aperture-based lensless camera with ptychography-inspired reconstruction (2021)

To overcome the resolution and noise limits in Fresnel zone aperture-based lensless cameras, two types of multi-shot imaging are proposed. Simulated results show these methods successfully suppress the effect of sensor noise and diffraction.
Identification of 1H-NMR Spectra of Xyloglucan Oligosaccharides: A\n Comparative Study of Artificial Neural Networks and Bayesian Classification\n Using Nonparametric Density Estimation (2020)

Proton nuclear magnetic resonance (1H-NMR) is a widely used tool for chemical\nstructural analysis. However, 1H-NMR spectra suffer from natural aberrations\nthat render computer-assisted automated identification of these spectra\ndifficult, and at times impossible. Previous efforts have successfully\nimplemented instrument dependent or conditional identification of these\nspectra. In this paper, we report the first instrument independent\ncomputer-assisted automated identification system for a group of complex\ncarbohydrates known as the xyloglucan oligosaccharides. The developed system is\nalso implemented on the world wide web (http://www.ccrc.uga.edu) as part of an\nidentification package called the CCRC-Net and is intended to recognize any\nsubmitted 1H-NMR spectrum of these structures with reasonable signal-to-noise\nratio, recorded on any 500 MHz NMR instrument. The system uses Artificial\nNeural Networks (ANNs) technology and is insensitive to the instrument and\nenvironment-dependent variations in 1H-NMR spectroscopy. In this paper,\ncomparative results of the ANN engine versus a multidimensional Bayes'\nclassifier is also presented.\n
Implementing a Cell-Centered, Agent-Based Framework with Flexible Environment Granularities using MASON and VTK (2016)

Many mechanistic explanations of cell-level phenomena exist from an observer perspective, yet explanations gathered from a cell's perspective could offer new insights. Agent-based modeling techniques are adept at modeling from an agent's perspective. We implement a framework that utilizes a non-traditional off-lattice environment, in 2- and 3-dimensions, using MASON and VTK, with an aim to help increase mechanistic understanding of biological phenomena. We discuss numerous technical considerations and algorithms that were adapted for the framework, and we demonstrate basic cell behavior for biological cells. As the demand for biomimetic models grows, the demand for new methods, such as the presented Delaunay and Voronoi off-lattice environment, also grows. Our implementation of the Delaunay and Voronoi off-lattice framework aims to help meet that need.
Relation between Irofulven (MGI-114) systemic exposure and tumor response in human solid tumor xenografts. (2002)

Irofulven is a novel, small molecular weight semisynthetic compound, derived from a family of mushroom toxins known as illudins. This DNA alkylating agent has a chemical structure unlike any other chemotherapeutic agent in clinical use. The molecule is currently being studied in several Phase I, II, and III trials. The objectives of this study were to evaluate the antitumor activity of Irofulven in a panel of 20 pediatric solid tumor xenografts and to relate the Irofulven systemic exposure, defined as area under the concentration time curve, to the antitumor dose associated with tumor regression in the tumor models. Irofulven was administered i.v. daily for 5 days with courses repeated every 21 days for a total of three cycles. The minimum effective dose of Irofulven causing objective regression (> or =50% volume regression) of advanced tumors was determined for each of 19 of 20 independently derived tumor models (12 brain tumors, 4 neuroblastomas, and 4 rhabdomyosarcomas). At the maximum tolerated dose for three cycles of treatment (4.6 mg/kg/day) objective regressions were determined in 14 of 18 tumor lines (78%). However, the dose-response relationship was acute. At 2 mg/kg only 3 of 15 tumors tested demonstrated objective regressions, and in 3 additional tumors volume regressions were not achieved at a higher dose level (3 mg/kg), hence were not additionally tested. After administering the maximum tolerated dose (tolerated for one or two cycles of treatment) of Irofulven, 7 mg/kg, to mice bearing sensitive and resistant human tumors plasma concentration-time profiles were determined. Tumors were highly sensitive to Irofulven, but the systemic exposure required for a significant rate of objective response in this panel of tumors is in excess of that achievable in patients at tolerable doses, using this schedule of drug administration.
Suppression of Blue Mold Symptom Development in Satsuma Mandarin Fruits Treated by Low-Intensity Blue LED Irradiation (2015)

Blue mold (Penicillium italicum) is a major postharvest pathogen of citrus. Here, we investigated the mitigating effect of blue light-emitting diode (LED) irradiation on blue mold in satsuma mandarin (Citrus unshiu Marc.) fruit after harvesting. We examined the growth and development of blue mold subjected to blue LED irradiation of two different intensities in vitro. High-intensity blue LED with an emission peak of 465 nm and fluency of 80 µmol·m−2·s−1, and low-intensity blue LED with an emission peak of 465 nm and fluency of 8 µmol·m−2·s−1 significantly reduced the growth of P. italicum. In addition, wounded fruits inoculated with P. italicum were irradiated with high- and low-intensity blue LED for 6 days and changes in blue mold symptoms were monitored. The results indicate that not only high-intensity, but also low-intensity blue LED treatment significantly reduced blue mold symptoms in fruit; the most pronounced inhibitory effect was exerted on P. italicum sporulation. These results show that treatment with low-intensity blue LED irradiation is sufficient to reduce blue mold symptom development and is a promising safe approach to control postharvest spoilage in mandarin fruit.
Risk of Incident Diabetes With Intensive-Dose Compared With Moderate-Dose Statin Therapy (2011)

In a pooled analysis of data from 5 statin trials, intensive-dose statin therapy was associated with an increased risk of new-onset diabetes compared with moderate-dose statin therapy.
Active Disturbance Rejection Control for Permanent Magnetic Toroidal Motor (2018)

The mathematical model for permanent magnetic toroidal motor is established in this paper, which based on the analysis of the structural features and the principle of electromagnetic transmission. The corresponding state equation is derived from the mathematical model. In order to improve the disturbance rejection ability, an active disturbance rejection controller for speed loop and current loop is designed. The controller is applied to perturbation analysis about the performance of the motor under a constant load and a load of a triangle wave respectively. And the control system is built in Simulink for simulation experiment, which achieves a good control effect.
Sporophytic control of pollen tube growth and guidance in grasses (2010)

Pollen tube growth and guidance in the female tissues of flowering plants is a long-studied and anatomically well-described process. A large number of gene products and chemical compounds involved have been identified in the last 20 years, and some underlying molecular mechanisms including self-incompatibility in the Brassicaceae, Solanaceae and Papaveraceae are now well understood. However, the largest part of the pollen tube pathway inside the transmitting tract towards the ovule harbouring the female gametophyte still requires intensive investigations. Especially in the economically most import plant family, the Poaceae or grasses, progamic pollen tube development is barely understood. Using maize as a model, we propose to divide pollen tube germination, growth and guidance towards the female gametophyte into five distinct phases. The model is adapted from Arabidopsis thaliana, taking anatomical differences and novel genetic and cellular studies into consideration. With the exception of Phase V, all phases seem to be under sporophytic control in grasses.
Ka-band Technologies for Small Spacecraft Communications via Relays and Direct Data Downlink (2016)

As the scientific capabilities and number of small spacecraft missions in the near Earth region increase, standard yet configurable user spacecraft terminals operating in Ka-band are needed to lower mission cost and risk and enable significantly higher data return than current UHF or S-band terminals. These compact Ka-band terminals are intended to operate with both the current and next generation of Kaband relay satellites and via direct data communications with near Earth tracking terminals. This presentation provides an overview of emerging NASA-sponsored and commercially provided technologies in software defined radios (SDRs) and transceivers and electronically steered antennas that will expand the use of NASA's common Ka-band frequencies: 22.55-23.15 GHz for forward data or uplink; and 25.5-27.0 GHz for return data or downlink. Data rates as high as 100s Mbps are possible via relays and over 1 Gbps via direct data downlink. Reductions in mass, power and volume come from integration and software definition of multiple radio functions, operations in Ka-band, high efficiency amplifiers and receivers, and compact, flat and vibration free electronically steered narrow beam antennas that cover up to 120 degrees field of regard. One of the technologies described in the presentation, the software defined near Earth space transceiver (SD-NEST) is intended to be compliant with NASA's space telecommunications radio system (STRS) standard for communications waveforms and hardware interoperability.
Silicone-based encapsulation of a cell culture measurement device under physiological conditions (2009)

Impedance measurement with interdigitated electrode structures (IDES) is suitable for monitoring concentration and proliferation of adherent biological cells [1]. In some applications [2] the sensor interface has to be operated in the humid environment where the cells are cultivated. There, the combination of the ambient humidity with ionic contaminations of the electronic components causes a drift in the sensor signals. We present an encapsulation based on polydimethylsiloxane (PDMS), a silicone, which reduces humidity-induced drift of the sensor signals to values clearly below 1%. Affection of the cell culture media or the cell culture by gas emission of the cured PDMS was not observed.
MRTFA augments megakaryocyte maturation by enhancing the SRF regulatory axis (2018)

Serum response factor (SRF) is a ubiquitously expressed transcription factor that binds DNA at CArG (CC[A/T]<sub>6</sub>GG) domains in association with myocardin-family proteins (eg, myocardin-related transcription factor A [MRTFA]) or the ternary complex factor family of E26 transformation-specific (ETS) proteins. In primary hematopoietic cells, knockout of either SRF or MRTFA decreases megakaryocyte (Mk) maturation causing thrombocytopenia. The human erythroleukemia (HEL) cell line mimics the effects of MRTFA on Mk maturation, and MRTFA overexpression (MRTFA<sup>OE</sup>) in HEL cells enhances megakaryopoiesis. To identify the mechanisms underlying these effects, we performed integrated analyses of anti-SRF chromatin immunoprecipitation (ChIP) and RNA-sequencing data from noninduced and phorbol ester (12-<i>O</i>-tetradecanoylphorbol-13-acetate [TPA])-induced HEL cells, with and without MRTFA<sup>OE</sup> We found that 11% of genes were upregulated with TPA induction, which was enhanced by MRTFA<sup>OE</sup>, resulting in an upregulation of 25% of genes. MRTFA<sup>OE</sup> increased binding of SRF to genomic sites and enhanced TPA-induced expression of SRF target genes. The TPA-induced genes are predicted to be regulated by SRF and ETS factors, whereas those upregulated by TPA plus MRTFA<sup>OE</sup> lack ETS binding motifs, and MRTFA<sup>OE</sup> skews SRF binding to genomic regions with CArG sites in regions relatively lacking in ETS binding motifs. Finally, ChIP-polymerase chain reaction using HEL cells and primary human CD34<sup>+</sup> cell-derived subpopulations confirms that both SRF and MRTFA have increased binding during megakaryopoiesis at upregulated target genes (eg, <i>CORO1A</i>). We show for the first time that MRTFA increases both the genomic association and activity of SRF and upregulates genes that enhance primary human megakaryopoiesis.