gebhart/patrepeval huggingface dataset:
A Combined Model- and Learning-Based Framework for Interaction-Aware Maneuver Prediction (2016)

This paper presents a novel online-capable interaction-aware intention and maneuver prediction framework for dynamic environments. The main contribution is the combination of model-based interaction-aware intention estimation with maneuver-based motion prediction based on supervised learning. The advantages of this framework are twofold. On one hand, expert knowledge in the form of heuristics is integrated, which simplifies the modeling of the interaction. On the other hand, the difficulties associated with the scalability and data sparsity of the algorithm due to the so-called curse of dimensionality can be reduced, as a reduced feature space is sufficient for supervised learning. The proposed algorithm can be used for highly automated driving or as a prediction module for advanced driver assistance systems without the need of intervehicle communication. At the start of the algorithm, the motion intention of each driver in a traffic scene is predicted in an iterative manner using the game-theoretic idea of stochastic multiagent simulation. This approach provides an interpretation of what other drivers intend to do and how they interact with surrounding traffic. By incorporating this information into a Bayesian network classifier, the developed framework achieves a significant improvement in terms of reliable prediction time and precision compared with other state-of-the-art approaches. By means of experimental results in real traffic on highways, the validity of the proposed concept and its online capability is demonstrated. Furthermore, its performance is quantitatively evaluated using appropriate statistical measures.
ChemInform Abstract: Substituted Thiol Derivatives of Vinyl Sulfone Dyes. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Geographic Object-Based Image Analysis – Towards a new paradigm (2013)

The amount of scientific literature on (Geographic) Object-based Image Analysis - GEOBIA has been and still is sharply increasing. These approaches to analysing imagery have antecedents in earlier research on image segmentation and use GIS-like spatial analysis within classification and feature extraction approaches. This article investigates these development and its implications and asks whether or not this is a new paradigm in remote sensing and Geographic Information Science (GIScience). We first discuss several limitations of prevailing per-pixel methods when applied to high resolution images. Then we explore the paradigm concept developed by Kuhn (1962) and discuss whether GEOBIA can be regarded as a paradigm according to this definition. We crystallize core concepts of GEOBIA, including the role of objects, of ontologies and the multiplicity of scales and we discuss how these conceptual developments support important methods in remote sensing such as change detection and accuracy assessment. The ramifications of the different theoretical foundations between the <i>'</i>per-pixel paradigm<i>'</i> and GEOBIA are analysed, as are some of the challenges along this path from pixels, to objects, to geo-intelligence. Based on several paradigm indications as defined by Kuhn and based on an analysis of peer-reviewed scientific literature we conclude that GEOBIA is a new and evolving paradigm.
Intradermal administration of DNA vaccine targeting Omicron SARS-CoV-2 via pyro-drive jet injector provides the prolonged neutralizing antibody production via germinal center reaction (2023)

Emerging SARS-CoV-2 Omicron variants are highly contagious with enhanced immune escape mechanisms against the initially approved COVID-19 vaccines. Therefore, we require stable alternative-platform vaccines that confer protection against newer variants of SARS-CoV-2. We designed an Omicron B.1.1.529 specific DNA vaccine using our DNA vaccine platform and evaluated the humoral and cellular immune responses. SD rats intradermally administered with Omicron-specific DNA vaccine via pyro-drive jet injector (PJI) thrice at 2-week intervals elicited high antibody titers against the Omicron subvariants as well as the ancestral strain. Indeed, the Omicron B.1.1.529-specific antibody titer and neutralizing antibody were higher than that of other strains. Longitudinal monitoring indicated that anti-spike (ancestral and Omicron) antibody titers decreased toward 30 weeks after the first vaccination dose. However, neutralization activity remained unaltered. Germinal center formation was histologically detected in lymph nodes in rats immunized with Omicron DNA vaccine. Ancestral spike-specific immune cell response was slightly weaker than Omicron spike-specific response in splenocytes with Omicron-adapted DNA vaccine, evaluated by ELISpot assay. Collectively, our findings suggest that Omicron targeting DNA vaccines via PJI can elicit robust durable antibody production mediated by germinal center reaction against this new variant as well as partially against the spike protein of other SARS-CoV-2 variants.
Epidemiology of rubella infection and genotyping of rubella virus in Cote d’Ivoire, 2012‐2016 (2018)

Rubella is a contagious disease caused by the rubella virus (RuV) that can lead to serious birth defects when women are infected in early pregnancy. This study aimed to describe the epidemiology and genetic diversity of rubella viruses in Cote d'Ivoire (CIV). Blood or oral fluid samples collected from suspected measles cases were first tested for the presence of measles specific IgM antibodies by enzyme-linked immunosorbent assay (ELISA). All measles IgM negative or indeterminate samples were tested for rubella IgM antibody using ELISA. Rubella-IgM-positive samples were tested by real-time reverse transcription polymerase chain reaction (RT-PCR) for the presence of rubella virus RNA. Real-time RT-PCR-positive RNA samples were used as template to amplify the 739 nt region used for rubella genotyping. PCR-positive samples were sequenced and phylogenetic analysis performed. Between 2012 and 2016, 4121 serums and 126 oral fluids were collected through the measles surveillance system. Of these, 3823 and 108 respectively were measles IgM negative or indeterminate. Subsequent testing for rubella found that 690 of 3823 (18%) serum samples and 25 of 108 (23%) oral fluid samples were rubella IgM-positive. The 739 nt segment of the E1 glycoprotein gene was amplified and sequenced for two serums and seven oral fluids samples. Phylogenetic analysis showed that the rubella viruses from CIV belonged to genotypes 1G (eight samples) and 2B (one sample). Rubella virus genotype 2B was found in CIV for the first time. These data contribute to baseline information on rubella virus strains found in CIV before the introduction of rubella vaccine.
High expression of cyclooxygenase‐2 in macrophages of human colonic adenoma (1999)

Cyclooxygenase (COX)-2 is a possible molecular target for suppression of colon carcinogenesis by non-steroidal anti-inflammatory drugs (NSAIDs). However, the expression of COX-2 in human colonic tumors during the adenoma-carcinoma sequence has not been elucidated. In the present study, we examined immuno-histochemically the expression and localization of the COX-2 protein in human colonic adenomas and cancers. Twelve human colonic adenomas and 9 advanced cancers were studied. Immunoreactive COX-2 was predominantly and strongly expressed in sub-epithelial interstitial cells broadly present in the surface area of adenomas. The staining pattern of macrophages was similar to that observed for COX-2 in adenomas. Adjacent normal colonic mucosa was negative for COX-2 expression. In contrast, COX-2 was relatively weakly expressed in both tumor cells and interstitial cells in advanced colon cancers. In conclusion, the target of NSAIDs in preventing colon carcinogenesis may be the COX-2 expressed in interstitial cells, possibly macrophages, of colonic adenomas. Int. J. Cancer 83:470–475, 1999. © 1999 Wiley-Liss, Inc.
Phenomenological Study of the Effect of Microstructural Evolution on the Thermal Fatigue Resistance of Pb-Free Solder Joints (2011)

Unlike SnPb solders, the thermal fatigue reliability of the Sn-Ag-Cu (SAC) solders is believed to be influenced significantly by both the initial and evolving microstructures. This paper presents a phenomenological study of the relationship between the initial SAC solder joint microstructure, the evolving microstructure, and the thermal fatigue performance measured by accelerated temperature cycling (ATC). To reflect the board assemblies that are in field use, commercial surface mount components with multiple geometries and materials and from different package assemblers were joined to the board with different lead free SAC alloys. The initial microstructures of the board level solder joints were altered in a variety of ways including: 1) varying the solder joint cooling rate; 2) varying the number of solder reflow exposures; and 3) exposure to different isothermal temperature exposures. In all cases the solder joint microstructure was exposed to one or more of these treatments prior to exposure to temperature cycling. In addition, some of the test boards were exposed to different cycling dwell times to determine if the microstructural evolution that occurred during ATC testing effected the respective characteristic lifetimes of the joints. The microstructural evolution was tracked and characterized with optical metallography and scanning electron microscopy. These results could have practical implications in terms of limiting the ability to develop acceleration factors and effective strain-based models for predicting Pb-free solder joint life.
5-GHz Obstructed Vehicle-to-Vehicle Channel Characterization for Internet of Intelligent Vehicles (2018)

Powered by the Internet of Things, the vehicular ad-hoc networks are expected to evolve into the Internet of Intelligent Vehicles in which each vehicle can be much more efficient in various vehicular and transportation applications. In order to realize this vision, a seamless low-latency and ultrareliable vehicle-to-vehicle (V2V) communication network is required. Thus, it is of importance to characterize the V2V channels in various realistic environments, especially when the line-of-sight between transmitter (Tx) and receiver (Rx) is obstructed. In this paper, we characterize obstructed V2V channels in the 5-GHz band through measurement-calibrated ray-tracing (RT) simulations. To begin, the main objects in the real world are divided into two groups: 1) the small-scale structures (e.g., lampposts, traffic signs, etc.) and 2) the large-scale structures (such as buildings and ground). Then, we integrate the radar cross sections of the small-scale structures into our RT simulator through a framework based on high frequency prediction techniques. For the large-scale structures, we calibrate the electromagnetic and scattering parameters of the large-scale structures through V2V channel measurements. After such integration and calibration, extensive RT simulations for V2V channels with Tx and Rx located on vehicles traveling in the opposite or same direction are realized with various antenna deployments in urban and open space environments, with and without sloped terrain. Based on the RT results, we characterize the path loss, shadow fading, and delay spread of the channel for each case, and show agreement with measured results in the literature for all these channel characteristics.
BER Analysis of Three-Phase XOR-and-Forward Relaying Using Alamouti STBC (2012)

In this paper we investigate the performance of two-way relaying that uses Alamouti space-time block code (STBC) and network coding. In this scheme, two nodes use Alamouti STBC to transmit their symbols to the relay consecutively in two phases. The relay detects and demodulates the transmitted symbols from the nodes, and then uses the bitwise-XOR operation to combine the detected bits. Then the relay modulates and broadcasts the XORed bits to the nodes using Alamouti STBC. In this paper, the bit error rate of the proposed scheme is derived for an uncorrelated Rayleigh fading channel with perfect channel estimation at receivers.
Human capability assessment (1982)

Contents: E.A. Fleishman, Introduction. M.D. Dunnette, Critical Concepts in the Assessment of Human Capabilities. D.A. Bownas, N.G. Peterson, Skill and Task Structure and Performance Acquisition. F.A. Muckler, Evaluating Productivity. I.L. Goldstein, V.M. Buxton, Training and Human Performance. L.F. Schoenfeldt, Intra-individual Variability in Performance. B.M. Bass, Individual Capability, Team Performance, and Productivity. J.E. Hunter, F.L. Schmidt, Fitting People into Jobs: The Impact of Personnel Selection on National Productivity.
Modeling of Calcium Leaching from Cement Hydrates Coupled with Micro-Pore Formation (2006)

A computational system for predicting the long-term degradation of cement hydrates due to calcium leaching is presented. The leaching of calcium ions from hardened cement hydrates is simulated as the multi-phase equilibrium of calcium in solid and liquid phases and their transport is formulated on the basis of thermodynamics. The time-dependent properties of cement hydrates associated with hydration, pore-structure development, and moisture transport are evaluated by integrating calcium leaching and statistical models of chemo-physics. The proposed model delivers reasonable predictions of calcium leaching in high-performance concrete with a low water-to-cement ratio as self-curing takes place.
Optimizing static calendar queues (2000)

The calendar queue is an important implementation of a priority queue that is particularly useful in discrete event simulators. We investigate the performance of the static calendar queue that maintains N active events. The main contribution of this article is to prove that, under reasonable assumptions and with the proper parameter settings, the calendar queue data structure will have constant (independent of N ) expected time per event processed. A simple formula is derived to approximate the expected time per event. The formula can be used to set the parameters of the calendar queue to achieve optimal or near optimal performance. In addition, a technique is given to calibrate a specific calendar queue implementation so that the formula can be applied in a practical setting.
Synthesis of Distributed Design Problems (2006)

Integrating autonomous disciplines into a complex system design problem amenable to solution presents a major challenge in realistic multidisciplinary design. We propose a linguistic approach to problem description, formulation, and solution we call reconfigurable multidisciplinary synthesis (REMS). REMS comprises an abstract language and a collection of processes that provide a means for dynamic reasoning about complex design problems in a range of contexts, spanning tasks from error checking and derivative computation to formulation and reformulation of multidisciplinary design problem statements.
Defect Modeling Using Fault Tuples (2006)

Fault tuples represent a defect modeling mechanism capable of capturing the logical misbehavior of arbitrary defects in digital circuits. To justify this claim, this paper describes two types of logic faults (state transition and signal line faults) and formally shows how fault tuples can be used to precisely represent any number of faults of this kind. The capability of fault tuples to capture misbehaviors beyond logic faults is then illustrated using many examples of varying degree of complexity. In particular, the ability of fault tuples to modulate fault controllability and observability is examined. Finally, it is described how fault tuples can and have been used to enhance testing tasks such as fault simulation, test generation, and diagnosis, and enable new capabilities such as interfault collapsing and application-based quality metrics
Epidemiology of Bovine Pestiviruses Circulating in Italy (2021)

Pestiviruses are widespread and economically important pathogens of cattle and other animals. <i>Pestivirus A</i> (formerly known as Bovine viral diarrhea virus 1, BVDV-1), <i>Pestivirus B</i> (Bovine viral diarrhea virus 2, BVDV-2), and <i>Pestivirus H</i> (HoBi-like pestivirus, HoBiPeV) species are infecting primarily cattle. Like other RNA viruses, pestiviruses are characterized by a high degree of genetic variability. This high rate of variability is revealed by the existence of a number of viral subgenotypes within each species. In cattle, the highest number of pestivirus subgenotypes has been documented in European countries, particularly in Italy. The aim of this review is to report an up-to-date overview about the genetic diversity of pestiviruses in Italian cattle herds. All three bovine pestiviruses species have been identified in cattle population with variable frequency and geographical distribution. The genetic diversity of Italian pestiviral strains may have diagnostic and immunological implications, affecting the performance of diagnostic tools and the full cross-protection elicited by commercially available vaccines. Implementation and strengthening of coordinated approaches for bovine pestivirus control in Italy are recommended. Therefore, it would be extremely important to increase control and restriction measures to the trade of cattle and biological products of bovine origin, including those containing fetal bovine serum.
FcγRIa–γ-chain complexes trigger antibody-dependent cell-mediated cytotoxicity (ADCC) in CD5+ B cell/macrophage IIA1.6 cells (1998)

Most receptors for immunoglobulins exist as multi-subunit complexes, with unique ligand binding alpha-chains, combined with accessory signalling (gamma-, beta-, or zeta-) chains. The myeloid class I receptor for IgG (FcgammaRIa) has been shown to be dependent on the FcR gamma-chain for surface expression in vivo. In this study we assess the capacity of FcgammaRIa-gamma-chain complexes expressed in IIA1.6 cells to trigger phagocytosis and ADCC. An intact immunoreceptor tyrosine-based activation motif (ITAM) signalling motif proved essential for triggering of biological function via the FcgammaRIa receptor complex. Both the FcR gamma-chain and the FcgammaRIIa-ITAM proved active in directing phagocytosis of Staphylococcus aureus and ADCC of erythrocytes, triggered by the FcgammaRIa complex. The capacity of FcgammaRIa to trigger phagocytic and cytolytic activity by IIA1.6 cells, both considered 'professional phagocyte' functions, motivated us to re-evaluate the cell lineage and developmental stage of IIA1.6 cells. Although originally described as mouse B lymphocytes, the IIA1.6 cells proved positive for non-specific esterase activity and expressed the CD5 antigen. These combined characteristics place the IIA1.6 cells within a unique CD5+ B cell/macrophage lineage, optimally suited for cell biological analyses of phagocyte receptors.
Biodegradable hyaluronic acid-based, nitric oxide-releasing nanofibers for potential wound healing applications (2021)

Nitric oxide (NO) is one of the smallest gas molecules with pharmaceutical and potential wound therapeutic effects due to its ability to regulate inflammation and eradicate bacterial infections. Recently, NO-releasing synthetic polymer-based nanofibers have become promising candidates for wound healing due to their facile functionalisation, tunable mechanical properties, and large effective surface areas. However, synthetic polymer-based nanofibers suffer from poor degradability in the physiological milieu, which restricts their use in <i>in vivo</i> applications. In this study, we developed biodegradable and nitric oxide-releasing nanofibers for potential wound healing applications. We synthesised dual-functionalised hyaluronic acid (HA) containing methacrylate groups and <i>N</i>-diazeniumdiolate (NONOate)-NO donor groups and capable of forming crosslinked, electrospun nanofibers, with an effective NO payload, through an electrospinning process and photoinitiated polymerisation. Nuclear magnetic resonance, Fourier transform infrared spectroscopy, and ultraviolet-visible spectroscopy confirmed the successful synthesis of the functionalised HA. Control over both the NO donor and HA concentrations allowed for the preparation of NO-releasing, HA-based nanofibers of varying diameters (240-490 nm), NO payloads (10-620 nmol mg<sup>-1</sup>), maximum amounts of NO released (160-8920 ppb mg<sup>-1</sup>), and NO release durations (1.5-20.2 h). Moreover, the NO-releasing nanofibers had good biodegradability and potential wound healing effects without any observed cytotoxicity. The biodegradable and NO-releasing HA-based nanofibers developed in this study have the potential application in wound healing.
Target direction estimation by MIMO radar using root-MUSIC with minimum redundancy array (2016)

Multiple-Input Multiple-Output (MIMO) radar which applies MIMO communication technology in the radar has attracted attention as a kind of high-resolution radar. In this paper, target direction is estimated by applying the MUSIC method to the minimum redundancy MIMO radar which has been used as the adaptive beamforming array. Furthermore, the Root-MUSIC method which has been limited to the uniform array is applied to the minimum redundancy array to reduce the computational load in the direction estimation.
Responsiveness of the Foot Function Index, AOFAS Clinical Rating Systems, and SF-36 after Foot and Ankle Surgery (2006)

This study demonstrated increased responsiveness of foot and ankle specific outcomes tools compared to the SF-36. However, the Bodily Pain sub-scale and Physical Component Summary scale of the SF-36 had levels of responsiveness approaching those of the FFI and AOFAS Systems after foot and ankle surgery. This suggests that the SF-36 may be used alone to monitor the outcomes in these patients without sacrificing adequate sensitivity to clinical change.
Isomeric Amino Alcohols from the Reaction of Styrene Oxide with Benzylamine (1952)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIsomeric Amino Alcohols from the Reaction of Styrene Oxide with BenzylamineColin L. Browne and Robert E. LutzCite this: J. Org. Chem. 1952, 17, 9, 1187–1193Publication Date (Print):September 1, 1952Publication History Published online1 May 2002Published inissue 1 September 1952https://pubs.acs.org/doi/10.1021/jo50009a002https://doi.org/10.1021/jo50009a002research-articleACS PublicationsRequest reuse permissionsArticle Views160Altmetric-Citations21LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts