gebhart/patrepeval huggingface dataset:
Technologies and Architectures of the Internet-of-Things (IoT) for Health and Well-being (2013)

The emerging technology breakthrough of the Internet-of-Things (IoT) is expected to offer promising solutions for food supply chain (FSC) and in-home healthcare (IHH), which may significantly contribute to human health and well-being. In this thesis, we have investigated the technologies and architectures of the IoT for these two applications as so-called Food-IoT and Health-IoT respectively. We intend to resolve a series of research problems about the WSN architectures, device architectures and system integration architectures. To reduce the time-to-market and risk of failure, business aspects are taken into account more than before in the early stage of technology development because the technologies and applications of IoT are both immature today. The challenges about enabling devices that we have addressed include: the WSN mobility and wide area deployment, efficient data compression in resource-limited wireless sensor devices, reliable communication protocol stack architecture, and integration of acting capacity to the low cost intelligent and interactive packaging (I2Pack). Correspondingly, the WAN-SAN coherent architecture of WSN, the RTOS-based and multiprocessor friendly stack architecture, the content-extraction based data compression algorithm, and the CDM-based I2Pack solution are proposed and demonstrated. At the system level, we have addressed the challenges about effective integration of scattered devices and technologies, including EIS and information integration architectures such as shelf-life prediction and real-time supply chain re-planning for the Food-IoT, and device and service integration architectures for the Health-IoT. Additionally, we have also addressed some challenges at the top business level, including the Value Chain Models and Value Proposition of the Food-IoT, and the cooperative ecosystem model of the Health-IoT. These findings are generic and not dependent on our proprietary technologies and devices. To be more generalized, we have demonstrated an effective research approach, the so-called Business-Technology Co-Design (BTCD), to resolve an essential challenge in nowadays research on the IoT -- the lack of alignment of basic technology and practical business requirements. We have shown its effectiveness by our design practice. It could be an instructive example of “the change of mindset” which is essential for the IoT research in the future.
Characterisation of Mcl‐1 cleavage during apoptosis of haematopoietic cells (2004)

Mcl-1 is essential for normal haematopoiesis, being required for lymphocyte development and maintenance. Its role in haematopoietic differentiation and development is associated with its function as an anti-apoptotic member of the Bcl-2 family of proteins although the underlining mechanism is poorly understood. We have characterized caspase cleavage of the Mcl-1 protein during apoptosis. Caspase cleavage resulted in the removal of the PEST regions from the protein and generation of a fragment containing the BH-1, -2 and -3 homology domains. Removal of the PEST regions did not appear to alter Mcl-1 stability, suggesting that these regions are not responsible for Mcl-1's short half-life. In addition, unlike cleavage of Bcl-2 and Bcl-X(L), which resulted in pro-apoptotic fragments, cleaved forms of Mcl-1 were unable to induce apoptosis. This novel regulation of Mcl-1 may have important implications not only for its role in apoptosis but also for the essential role it plays in the differentiation and development of haematopoietic cells.
Tooling geometry optimization for compensation of cure-induced distortions of a curved carbon/epoxy C-spar Part A Applied science and manufacturing (2014)

The respect of the manufacturing tolerances is a challenging issue due to the complex distortions caused by the curing process, being sometimes a major obstacle to an increasing use of composites in aeronautics. The cure-induced distortions are modeled and mitigated owing to the development of a computational mold compensation strategy. An in-house surrogate-based optimizer coupled to three-dimensional curing simulations, is used to iteratively alter the shape of the mold in order to minimize the discrepancy with respect to the nominal geometry. Two parametrization strategies are proposed and applied to a generic curved C-spar geometry. One strategy consists in the characterization of the major distortion modes caused by the curing process, and in the parametrization of the geometry to compensate for each mode. The other strategy is to select a number of control points which can move freely in space to find the optimal configuration. Each method performs well but in a different manner, and the optimal choice depends on the industrial specifications of the problem.
AN AESTHETIC ANTHROPOLOGICAL SURVEY OF THE HEIYI-ZHUANG (2003)

The artistic cultural customs of the minority Zhuang in black (the so called Heiyi Zhuang) are closely connected to their everyday life. The Heiyi Zhuang are still living in the stage of natural economy. The arduous living conditions force the people to rely greatly on the community. In order to survive and develop under the adverse natural circumstances, the Heiyi Zhuang has formed its unique national tradition, such as upholding the common interest of the community, exercising the rigorous system of marrying within the community. This is also reflected in their artistic and cultural customs. As an aesthetic ideology, the dance and folksong of the Heiyi Zhuang embody a concentrated reflection of their living situation and of the transcendence of the hardship of their life.
Commissioning a passive‐scattering proton therapy nozzle for accurate SOBP delivery (2009)

Proton radiotherapy centers that currently use passively scattered proton beams do field specific calibrations for a non-negligible fraction of treatment fields, which is time and resource consuming. Our improved understanding of the passive scattering mode of the IBA universal nozzle, especially of the current modulation function, allowed us to re-commission our treatment control system for accurate delivery of SOBPs of any range and modulation, and to predict the output for each of these fields. We moved away from individual field calibrations to a state where continued quality assurance of SOBP field delivery is ensured by limited system-wide measurements that only require one hour per week. This manuscript reports on a protocol for generation of desired SOBPs and prediction of dose output.
Shotgun proteomics of human bile in hilar cholangiocarcinoma (2011)

Abstract The need to find biomarkers for hepatobiliary diseases including cholangiocarcinoma (CCA) has led to an interest in using bile as a proximal fluid in biomarker discovery experiments, although there are inherent challenges both in its acquisition and analysis. The study described here greatly extends previous studies that have started to characterise the bile proteome. Bile from four patients with hilar CCA was depleted of albumin and immunoglobulin G and analysed by GeLC‐MS/MS. The number of proteins identified per bile sample was between 378 and 741. Overall, the products of 813 unique genes were identified, considerably extending current knowledge of the malignant bile proteome. Of these, 268 were present in at least 3 out of 4 patients. This data set represents the largest catalogue of bile proteins to date and together with other studies in the literature constitutes an important prelude to the potential promise of expression proteomics and subsequent validation studies in CCA biomarker discovery.
Corrections for X-Ray Polychromaticity Effects on Three-Dimensional Reconstruction (1976)

The effect of polychromaticity on the reconstruction of attenuation coefficients from X-ray transmissions is presented by computer simulations of two simple phantoms. The distortions resulting from different amounts of X-ray beam hardening along different paths can be reduced by an equivalent water path analysis and a two parameter energy independent analysis. The first method transforms the projected paths into equivalent (i.e., same total transmission) water path lengths. The second method uses two spectra to factor out the energy independent parts of the photoelectric and Compton coefficients. This solution also involves conversion into equivalent water path lengths.
Structural and electrical characterization of AuPtAlTi Ohmic contacts to AlGaN∕GaN with varying annealing temperature and Al content (2008)

The effect of varying annealing temperature and Al layer thickness on the structural and electrical characteristics of AuPtAlTi∕AlGaN∕GaN Ohmic contact structures has been systematically investigated. The relationship between annealing temperature, Al content, interfacial microstructure, surface planarity, and contact resistance is examined. In particular, the presence of a detrimental low temperature Pt–Al reaction is identified. This is implicated in both the requirement for a higher Al:Ti ratio than is required for related AuPdAlTi contact schemes and through the degraded temperature dependent resistance behaviour of the annealed AuPtAlTi contacts.
Demographic profile of patients seeking teleophthalmology consultations through e-Sanjeevani: Retrospective analysis of 5138 patients from North India (2022)

e-Sanjeevani is an effective way to provide teleconsultations to patients in remote locations. The majority of the patients seeking ophthalmology consultations can be managed conservatively. Patients requiring surgical intervention can be referred timely, thus avoiding any delay in treatment.
Toxicological and bioactivity evaluation of blackcurrant press cake, sea buckthorn leaves and bark from Scots pine and Norway spruce extracts under a green integrated approach (2021)

Aqueous extracts from blackcurrant press cake (BC), Norway spruce bark (NS), Scots pine bark (SP), and sea buckthorn leaves (SB) were obtained using maceration and pressurized hot water and tested for their bioactivities. Maceration provided the extraction of higher dry matter contents, including total phenolics (TPC), anthocyanins, and condensed tannins, which also impacted higher antioxidant activity. NS and SB extracts presented the highest mean values of TPC and antioxidant activity. Individually, NS extract presented high contents of proanthocyanidins, resveratrol, and some phenolic acids. In contrast, SB contained a high concentration of ellagitannins, ellagic acid, and quercetin, explaining the antioxidant activity and antibacterial effects. SP and BC extracts had the lowest TPC and antioxidant activity. However, BC had strong antiviral efficacy, whereas SP can be considered a potential ingredient to inhibit α-amylase. Except for BC, the other extracts decreased reactive oxygen species (ROS) generation in HCT8 and A549 cells. Extracts did not inhibit the production of TNF-alpha in lipopolysaccharide-stimulated THP-1 macrophages but inhibited the ROS generation during the THP-1 cell respiratory burst. The recovery of antioxidant compounds from these by-products is incentivized for high value-added applications.
Alternative Fuels on a Small High Speed Turbocharged D.I. Diesel Engine (1983)

&lt;div class="htmlview paragraph"&gt;The aim of this paper is to indicate what modifications are recommended in order to make a small light-duty d.i. diesel engine suitable for alternative fuels such as vegetable oil or gasoline diesel mixtures.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;The paper further gives performance charts and test results which indicate that good suitability can be obtained for alternative fuels.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;The authors believe that the light-duty d.i. diesel will rapidly became the most common car and tractor engine and that the multi-fuel suitability is an advantage in some markets as of today and will increasingly be so.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;The introduction of an inexpensive and reliable engine being able to run on a wide range of alternative fuels can be of major environmental, economical and political consequence.&lt;/div&gt;
The Tetraspanin CD53 Regulates Early B Cell Development by Promoting IL-7R Signaling (2019)

The tetraspanin CD53 has been implicated in B cell development and function. CD53 is a transcriptional target of EBF1, a critical transcription factor for early B cell development. Further, human deficiency of CD53 results in recurrent infections and reduced serum Igs. Although prior studies have indicated a role for CD53 in regulating mature B cells, its role in early B cell development is not well understood. In this study, we show that CD53 expression, which is minimal on hematopoietic stem and progenitor cells, increases throughout bone marrow B cell maturation, and mice lacking CD53 have significantly decreased bone marrow, splenic, lymphatic, and peripheral B cells. Mixed bone marrow chimeras show that CD53 functions cell autonomously to promote B lymphopoiesis. <i>Cd53<sup>-/-</sup></i> mice have reduced surface expression of IL-7Rα and diminished phosphatidylinositol 3 kinase and JAK/STAT signaling in prepro- and pro-B cells. Signaling through these pathways via IL-7R is essential for early B cell survival and transition from the pro-B to pre-B cell developmental stage. Indeed, we find increased apoptosis in developing B cells and an associated reduction in pre-B and immature B cell populations in the absence of CD53. Coimmunoprecipitation and proximity ligation studies demonstrate physical interaction between CD53 and IL-7R. Together, these data, to our knowledge, suggest a novel role for CD53 during IL-7 signaling to promote early B cell differentiation.
Silver Extraction for Pollution Control of Photographic Fixing Solution with Tetramethylthiuram Disulfide (1996)

Abstract Silver recovery from photographic fixing solutions can be performed by solvent extraction with thiuram disulfides. Tetramethylthiuram disulfide (TMTDS) was selected for further studies because it had the highest distribution ratio among the three extractants. Its selectivity for silver extraction from a thiosulfate medium and from an analytical photographic fixing solution were evaluated. A 1 : 1 silver(I)–TMTDS complex is formed. For a one-stage and one-hour silver(I) extraction process, a 96% recovery was obtained from an analytical fixing solution containing 1 g dm−3 silver(I), starting with a 0.02 M (1 M = mol dm−3) TMTDS solution. The possible extraction mechanism involves the reduction of TMTDS in the presence of thiosulfate ions, followed by chelation of the silver(I) with the reduced TMTDS. Effective stripping can be performed by using 3 M hydrochloric acid. By dilution of the fixing solution with water (1 : 1), and the use of 0.1 M TMTDS, recycling of the organic phase between the extraction and stripping stages for silver extraction can be achieved in a few times. The results for the analytical solutions were further shown to be applicable to a black and white photographic industrial solution.
Radial force of coronary stents: A comparative analysis (1999)

High radial force has become an essential feature of new coronary stents. These stents are expected to exhibit sufficient radial force and minimum radial recoil when deployed in atheromatous lesions of various morphologies. The aim of this study was to compare the radial force of 17 coronary stents in vitro (Anglodynamics, ACS Multilink, AVE Micro II and GFX, Bard XT, Biocompatibles PC, Cook GR II, Cordis Crossflex, Hexacath Freedom, Johnson & Johnson PS 153'PS 154, and Crown, Medtronic Wiktor and BeStent BEL-15, Saint-Come SC 1616, Scimed Nir 7 and 9). Two in vitro mechanical tests were performed to assess the stent radial force. The first test measured the deformation of coronary stents in a V-stand by using a deformation controlled by a dynamometer based on a longitudinal generatrix. The precision was of 1 micron. This comparative test highlighted the appreciable variation in behavior of the range of tested stents in terms of resistance to local compression. The line graphs obtained show a very small (and in some cases nonexistent) purely elastic behavior area in the stents, with this result reflecting a small (<0.4 Newtons) range of forces applied to all stents. Above this value, the stents did not return to their size before compression and the line graph remains approximately linear for a long period. It was therefore possible to distinguish between two families of stents on the basis of the presence or absence of this elastic area. In the second test, the stent was deployed in a 3.0-mm elastic tube and a pressure gradient created between the interior and exterior of the tube. The precision was of 50 microns. A typical line graph of the pressure-diameter relationship was recognizable for a given stent. No difference in behavior between the different coronary stents was noted up to 0.3 x 10(5) Pa; subsequently, after 0.3 x 10(5) Pa, sizable deformation differences were visible between the least resistant stent, the BeStent BEL-15, and the most resistant stent, the Crossflex.
Optimizing the pumping configuration for the power scaling of in-band pumped erbium doped fiber amplifiers (2012)

A highly efficient (~80%), high power (18.45 W) in-band, core pumped erbium/ytterbium co-doped fiber laser is demonstrated. To the best of our knowledge, this is the highest reported efficiency from an in-band pumped 1.5 µm fiber laser operating in the tens of watts regime. Using a fitted simulation model, we show that the significantly sub-quantum limit conversion efficiency of in-band pumped erbium doped fiber amplifiers observed experimentally can be explained by concentration quenching. We then numerically study and experimentally validate the optimum pumping configuration for power scaling of in-band, cladding pumped erbium doped fiber amplifiers. Our simulation results indicate that a ~77% power conversion efficiency with high output power should be possible through cladding pumping of current commercially available pure Erbium doped active fibers providing the loss experienced by the cladding guided 1535 nm pump due to the coating absorption can be reduced to an acceptable level by better coating material choice. The power conversion efficiency has the potential to exceed 90% if concentration quenching of erbium ions can be reduced via improvements in fiber design and fabrication.
Treatment of Staphylococcus aureus skin infection in vivo using rifampicin loaded lipid nanoparticles (2020)

We have previously reported on a novel nanoparticle formulation that was effective at killing <i>Staphylococcus aureus in vitro</i>. Here, we report for the first time, the antibacterial effects of a lipidic nano-carrier containing rifampicin (NanoRIF) which can be used to successfully treat Methicillin-Resistant <i>S. aureus</i> (MRSA) infection at a reduced antibiotic dosage compared to the free drug in a skin wound model in mice. The formulation used contains the lipid monoolein, a cationic lipid <i>N</i>-[1-(2,3-dioleoyloxy)propyl]-<i>N</i>,<i>N</i>,<i>N</i>-trimethylammonium methyl-sulfate (DOTAP) and the antibiotic. We have shown that rifampicin-loaded nanoparticles are more effective at treating infection in the skin wound model than the antibiotic alone. Cryo-TEM was used to capture for the first time, interactions of the formed nanoparticles with the cell wall of an individual bacterium. Our data strongly indicate enhanced binding of these charged nanoparticles with the negatively charged bacterial membrane. The efficacy we have now observed <i>in vivo</i> is of significant importance for the continued development of nanomedicine-based strategies to combat antibiotic resistant bacterial skin infections.
Exploiting SMART pass filter deactivation detection to minimize inappropriate subcutaneous implantable cardioverter defibrillator therapies: a real-world single-centre experience and management guide (2023)

To reduce the risk of IT, the cause of the SP deactivation should be investigated, and appropriate reprogramming, device, or lead modifications made. Utilizing the alert for SP deactivation and electrograms could pro-actively prevent IT.
GENVIEW: a portable source-level debugger for macrocell generators (1991)

An effective layout design method for VLSI macrocell is presented in this paper. The method describes a way to write, to test and to validate efficient Full-Custom generators and tilers. First, after a brief overview of the design methodology of tilers, the GENLIB C-library of procedural design functions is described. Second, GENVIEW, a portable and graphic layout debugger for the interactive testing of generators, is detailed.
Efficient coding and detection of ultra-long IDs for visible light positioning systems (2018)

Visible light positioning (VLP) is a promising technique to complement Global Navigation Satellite System (GNSS) such as Global positioning system (GPS) and BeiDou Navigation Satellite System (BDS) which features the advantage of low-cost and high accuracy. The situation becomes even more crucial for indoor environments, where satellite signals are weak or even unavailable. For large-scale application of VLP, there would be a considerable number of Light emitting diode (LED) IDs, which bring forward the demand of long LED ID detection. In particular, to provision indoor localization globally, a convenient way is to program a unique ID into each LED during manufacture. This poses a big challenge for image sensors, such as the CMOS camera in everybody's hands since the long ID covers the span of multiple frames. In this paper, we investigate the detection of ultra-long ID using rolling shutter cameras. By analyzing the pattern of data loss in each frame, we proposed a novel coding technique to improve the efficiency of LED ID detection. We studied the performance of Reed-Solomon (RS) code in this system and designed a new coding method which considered the trade-off between performance and decoding complexity. Coding technique decreases the number of frames needed in data processing, significantly reduces the detection time, and improves the accuracy of detection. Numerical and experimental results show that the detected LED ID can be much longer with the coding technique. Besides, our proposed coding method is proved to achieve a performance close to that of RS code while the decoding complexity is much lower.
Phonon Viscosity (1969)

The Boltzmann equation for thermal phonons in a dielectric crystal in the presence of a slowly varying but otherwise arbitrary, strain field is solved formally by expanding the phonon distribution function in terms of eigenfunctions of the collision operator. The macroscopic stress is then calculated in terms of the macroscopic strain and the phonon distribution function by using the quasiharmonic approximation. The resulting equation for the stress is of the same form as that given by thermoelasticity, except for the presence of an extra term which is linear in the strain rate. The coefficient of the strain rate in this term is identified with the phonon viscosity tensor, and a formal expression for this tensor is obtained.