gebhart/patrepeval huggingface dataset:
Boosting multi-socket cache-coherency with low-latency silicon photonic interconnects (2015)

Speed-up in computing systems today is most often accomplished by increasing parallelism in both hardware and software. Parallel applications residing wholly on a single multi-core chip generally utilize implicit inter-thread communication via shared memory managed by cache-coherency mechanisms. However, increasing parallelism by creating coherent domains across many chips poses new challenges. In this work, we illustrate the sensitivity of various applications on a theoretical four-socket system to the latency of their coherency traffic, and show that current solutions, such as Quick Path Interconnect (QPI) and HyperTransport (HT), could benefit greatly from a lower latency communication medium. Then, we propose a silicon photonic inter-chip network that achieves very low-latency and falls within a reasonable power budget.
TinyLTS: Efficient network-wide Logging and Tracing System for TinyOS (2011)

Logging and tracing are important methods to gain insight into the behavior of sensor network applications. Existing generic solutions are often limited to nodes with a direct serial connection and do not provide the required efficiency for network-wide logging. Instead, this is often realized by application-specific subsystems developed for custom logging statements. In this paper, we present TinyLTS - a generic and efficient Logging and Tracing System for TinyOS. TinyLTS consists of a compiler extension that separates dynamic from static information at compile time, a declarative solution for inserting logging statements, an extensible framework for flexible storing and transmitting of logging data and a frontend for recombining dynamic and static information. Our system provides concise yet expressive programming abstractions for the developer combined with efficiency comparable to custom solutions.
Supporting intercultural collaboration with dynamic feedback systems (2009)

Intercultural collaboration is often hampered by the manner in which teams communicate, or fail to com-municate, their ideas, concerns, and feelings. Computer-mediated communication and the virtual nature of collaboration tend to exacerbate such communication issues into problems of conversation dominance, misattribution, and group conflict. New communication tools have the potential to mitigate some of these problems by augmenting individuals' and team's awareness of their communication inputs and processes. We explore how such feedback affects the communication content, attention distribution, and affective states of Chinese and American collaborators engaged in a creative de-sign task. We describe our tool, present preliminary findings from an ongoing lab experiment, and discuss next steps in our research regarding ways of detecting the impact of real-time conversation feedback in inter-cultural collaboration environments.
Transient Pig Motion Through Non-Isothermal Gas and Liquid Pipelines (2000)

Simulation of the dynamics of pigs moving through non-isothermal pipelines is presented. The differential mass, linear momentum and energy equations were numerically solved by a finite difference numerical scheme, for compressible flow through pipelines. The fluid flow equations were combined with an equation representing a force balance on the pig. Pressure forces developed due to flow through by-pass holes in the pig, pig acceleration and pig/pipe contact forces were considered. A stick/slip model was developed to account for the distinct friction regimes that prevail depending on whether the pig is stopped or in motion. An adaptive grid technique was employed to account for the moving pig. Heat losses to the ambient play an important role in the fluid temperature distribution. However, for the test cases conducted, the temperature variations caused virtually no effect on the pig dynamics.
Medical Care for Tuberculosis-HIV-Coinfected Patients in Russia with Respect to a Changeable Patients’ Structure (2022)

To date, tuberculosis (TB) remains the primary cause of mortality in human immunodeficiency virus (HIV) patients in Russia. Since the beginning of 2000, a sharp change in the HIV patients' structure, to the main known risk factors for HIV infection has taken place in Russia. The transmission of HIV through injectable drug use has begun to decline significantly, giving way to the prevalence of sexual HIV transmission today. These changes may require adjustments to organizational approaches to anti-TB care and the treatment of HIV-positive patients. Our study is aimed at identifying changes in TB-HIV coinfection patients' structures in 2019 compared to 2000. Based on the results obtained, our goal was to point out the parameters that need to be taken into account when developing approaches to improve the organization of TB control care for people with HIV infection. We have carried out a cross-sectional, retrospective, epidemiological study using government TB registry data from four regions in two federal districts of Russia in 2019. The case histories of 2265 patients from two regions with high HIV prevalence, which are part of the Siberian Federal District of Russia, and 89 patient histories from two regions of low HIV prevalence, which are part of the Central Federal District of Russia, were analyzed. We found that parenteral transmission (69.4%) remains the primary route of HIV transmission among the TB-HIV coinfected. The unemployed of working age without disability account for 80.2% of all coinfected people, while the formerly incarcerated account for 53.7% and the homeless account for 4.1%. Those with primary multidrug-resistant TB (MDR-TB) comprise 56.2% of HIV-TB patients. When comparing the incidence of coinfection with HIV among TB patients, statistically significant differences were obtained. Thus, the chances of coinfection increased by 4.33 times among people with active TB (95% CI: 2.31; 8.12), by 2.97 times among people with MDR-TB (95% CI: 1.66; 5.32), by 5.2 times in people with advanced processes in the lungs, including destruction, (95% CI: 2.78; 9.7), as well as by 10.3 times in the case of death within the first year after the TB diagnosis (95% CI: 2.99; 35.5). The absence of data for the presence of TB during preventive examination was accompanied by a decrease in the chances of detecting coinfection (OR 0.36; 95% CI: 0.2; 0.64). We have identified the probable causes of the high incidence of TB among HIV-infected: HIV-patient social maladaptation usually results in delayed medical care, leading to TB treatment regimen violations. Furthermore, self-administration of drugs triggers MDR-TB within this group. Healthcare providers should clearly explain to patients the critical importance of immediately seeking medical care when initial TB symptoms appear.
LONG-TERM FOLLOWUP OF NEOADJUVANT HORMONE THERAPY BEFORE RADICAL PROSTATECTOMY: MEMORIAL SLOAN-KETTERING CANCER CENTER RESULTS (2009)

The functional outcome of a nerve-sparing radical prostatectomy (RP) depends on the knowledge of autonomic nerve distribution in correlation to the prostate.Recent literature has focused predominantly on the anterior prostate; this study evaluates the nerve distribution on the entire prostate, using a two-dimensional approach.From 17 non-nerve-sparing (NS) RP specimens, 77 whole mounted serial sections were immunostained with PGP9.5 and analyzed.Each prostate half was divided into 12 sectors (three levels: apex, mid-part, base; four courses: anterior, anterolateral, posterolateral, posterior).The extracapsular nerves were counted and classified by size (>200 μm or ≤200 μm).Approximately two-thirds of the nerves were located in the posterolateral while 26.3/27.0% were located in the anterior and anterolateral. In the anterolateral, along the base–apex direction, the nerves decreased whereas they increased in the posterior. In the anterior, the highest counts were found in the mid-prostate. PGP 9.5 stain helps to determine the extracapsular nerve distribution, however, it does not allow a functional allocation.The nerve course expands from the base in the mid-part to the anterior sector, before it narrows towards the apex in the posterior lateral and posterior sectors. Therefore, it is recommended that the surgeon focus on nerve preservation in particular at the apex, starting in the anterior at the mid section as well as the common posterolateral course.
Calibrating electro-optic sampling systems (2002)

We apply frequency-domain impedance mismatch corrections to a temporal electro-optic sampling system and use it to characterize the magnitude and phase response of a photoreceiver that is physically far removed from the point where the voltage waveforms are measured. We identify and evaluate additional sources of measurement uncertainty.
Latency, thermal stability, and identification of an inhibitory compound of mirolysin, a secretory protease of the human periodontopathogen Tannerella forsythia (2021)

Mirolysin is a secretory protease of <i>Tannerella forsythia</i>, a member of the dysbiotic oral microbiota responsible for periodontitis. In this study, we show that mirolysin latency is achieved by a "cysteine-switch" mechanism exerted by Cys23 in the N-terminal profragment. Mutation of Cys23 shortened the time needed for activation of the zymogen from several days to 5 min. The mutation also decreased the thermal stability and autoproteolysis resistance of promirolysin. Mature mirolysin is a thermophilic enzyme and shows optimal activity at 65 °C. Through NMR-based fragment screening, we identified a small molecule (compound (cpd) <b>9</b>) that blocks promirolysin maturation and functions as a competitive inhibitor (<i>K</i><sub>i</sub> = 3.2 µM), binding to the S1' subsite of the substrate-binding pocket. Cpd <b>9</b> shows superior specificity and does not interact with other <i>T. forsythia</i> proteases or Lys/Arg-specific proteases.
State-Based Encoding of Large Asynchronous Controllers (2018)

State encoding is one of the fundamental problems in the synthesis of asynchronous controllers. The requirement for a correct hazard-free implementation imposes severe constraints on the way encoding signals can be inserted in the specification of a controller. Even though some specification formalisms, such as burst-mode machines or signal transition graphs, enable the specification of behaviors at the event level, the state encoding methods that provide the best good-quality solutions work at the state level. This imposes a severe limitation on the size of the controllers that can be handled by these methods. This paper proposes a method to solve the encoding problem for large asynchronous controllers using state-based methods. It is based on an iterative process of projection and re-composition that reduces the size specification by hiding signals, partially solves the encoding problem at the state level, and re-composes the original specification using a synchronous product. The process iterates until all encoding conflicts have been solved. The method is proved to preserve the behavior of the specification (branching bisimilarity) and shown to be capable of providing good-quality solutions for controllers of more than 100 signals and 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">6</sup> states.
Comparative Analysis for the Measurement of Head Accelerations in Ice Hockey Helmets Using Non-Accelerometer Based Systems (2014)

Head impact research involving accelerometer-based sensors in sports helmets has been well documented over the past decade. Practical methods for using accelerometer arrays present significant power management issues and a requirement for high-resolution data during direct head impact injury. The objective of this study was to investigate a reliable and affordable method for measuring direct head impacts for large-scale populations by using electromechanically activated force switches instead of accelerometers. An embedded microprocessor and software algorithm captured and calculated voltage activation of the force switches between 80–100 KHz. Laboratory studies conducted on a monorail drop tower using a magnesium headform demonstrated the ability to correlate headform acceleration to algorithm-reported acceleration. Impacts were performed on hockey helmets at 2.0, 2.5, and 3.0 m/s for an aggregate percent difference of 8.9 % at the front, front boss, side, rear boss, and rear impact locations, respectively. The use of force switch sensors affixed to sports helmets is viable at monitoring direct helmet impacts. The sensors produced reliable reported linear accelerations on a monorail drop tower.
Abstract 2375: Rapid unbiased enrichment (negative selection) of circulating non-hematopoietic tumor cells directly from whole blood (2012)

Abstract There is increasing interest in analyzing circulating non-hematopoietic tumor cells (CTC) in peripheral blood to evaluate disease progression or response to treatment; however, CTC enrichment is required prior to most analytic procedures. The ideal enrichment method would be rapid, permit a high recovery of viable CTC, and would be independent of the expression of specific epithelial cell surface markers, since CTCs in the peripheral blood may be undergoing EMT (epithelial mesenchymal transition) and may not express epithelial markers. RosetteSep™ CD45 depletion of hematopoietic cells directly from whole blood meets these criteria. However, RosetteSep™ enrichment of CTC involves density gradient centrifugation, which entails careful layering of the sample over the density gradient medium and careful pipetting to remove the enriched cells after centrifugation. Centrifugation must be performed with the brake off to avoid disturbing the enriched cell layer, further lengthening the process. SepMate™, a centrifugation tube with a specialized insert, was developed to minimize mixing of the sample with the density gradient medium, thus allowing rapid layering of the sample on the density gradient medium and easy pouring off of the enriched cells after centrifugation. We compared CTC enrichment using RosetteSep™ and the standard tubes and protocol with RosetteSep™ using SepMate™ tubes and reduced cocktail incubation and spin times on 5 donor whole blood samples seeded with ∼1% CAMA cells. Purity of viable (PI negative) CTC obtained with SepMate™ with RosetteSep™ was 85 ± 7%; purity of CTC obtained with RosetteSep™ alone was 91 ± 5% (no significant difference, paired t test, p=0.050). Purity of CTC obtained with density gradient centrifugation only (no RosetteSep™), either with or without SepMate™, was 4 ± 2%. There was no significant difference in the recovery of enriched CTC under any of the conditions tested (RosetteSep™ ± SepMate™, SepMate™ alone, density gradient separation alone, Tukey-Kramer test, p&amp;gt;0.05). CTC enrichment was accomplished in &amp;lt;40 min using SepMate™ with RosetteSep™. Simplifying the layering and layer removal step makes the entire process easily scalable to processing multiple samples simultaneously. Utilizing this method, CTCs can be enriched directly from whole blood without bias regarding their surface antigen expression. Large samples can be rapidly volume-reduced in preparation for detailed examination in a microfluidic device. Finally, enriched CTC are not labeled with antibodies or beads; there is nothing to interfere with subsequent further enrichment, culture, or evaluation. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 103rd Annual Meeting of the American Association for Cancer Research; 2012 Mar 31-Apr 4; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2012;72(8 Suppl):Abstract nr 2375. doi:1538-7445.AM2012-2375
Underwater scattering targets made of polystyrene foam (1992)

A versatile method is described of casting expandable polystyrene beads in small quantities for laboratory use as surface scattering targets. The method requires no specialized equipment and does not require careful process control. The making of one such target is described, a four-period sawtooth wedge grating. Backscattering was measured and compared favorably with a one-dimensional Fresnel–Kirchhoff model.
Topical Treatment With Liposomal Sodium Copper Chlorophyllin Complex in Subjects With Facial Redness and Erythematotelangiectatic Rosacea: Case Studies. (2015)

Physicians are often presented with patients complaining of facial redness and difficult to control rosacea. The water soluble sodium copper chlorophyllin complex has been shown to have anti-oxidant, anti-inflammatory, and anti-bacterial activities in vitro and anti-redness, pore reduction, and anti-acne activities in pilot clinical studies. In these case studies, the safety and efficacy of a topical gel containing a liposomal suspension of sodium copper chlorophyllin complex was assessed in subjects with facial redness and erythematotelangiectatic rosacea.
Tau Positron Emission Tomographic Imaging in the Lewy Body Diseases (2016)

Patients with Lewy body disease manifest a spectrum of tau pathology. Cortical aggregates of tau are common in patients with DLB and in PD-impaired patients, even in those without elevated amyloid levels. When present, tau deposition is associated with cognitive impairment. These findings support a role for tau copathology in the Lewy body diseases.
Self-supervised Representation Learning for Speech Processing (2022)

Hung-yi Lee, Abdelrahman Mohamed, Shinji Watanabe, Tara Sainath, Karen Livescu, Shang-Wen Li, Shu-wen Yang, Katrin Kirchhoff. Proceedings of the 2022 Conference of the North American Chapter of the Association for Computational Linguistics: Human Language Technologies: Tutorial Abstracts. 2022.
DESIGN OF STABLE 3D RECURSIVE DIGITAL FILTERS USING 3-VARIABLE VERY STRICTLY HURWITZ POLYNOMIAL (2000)

In this paper, methods for generating 3-variable Very Strictly Hurwitz Polynomials (VSHP's) are presented. It is shown that the derived 3-variable VSHP's could be used to design stable three-dimensional digital filters satisfying prescribed magnitude specifications.
Bainite in Steels (2019)

This is the third edition of the book, much expanded to include and incorporate important developments in the subject over the last fifteen years. The book represents a comprehensive treatise on all aspects of the bainite transformation, from the choreography of atoms during the phase change to length scales that are typical of engineering applications. The alloy design that emerges from this explains the role of solute additions, and the pernicious effects of impurities such as hydrogen. The picture presented is self-consistent and therefore is able to guide the reader on the exploitation of theory to the design of some of the most exciting steels, including the world’s first bulk nanostructured metal.
Phonon scattering cross section of polydispersed spherical nanoparticles (2006)

An approximate analytical solution is proposed to estimate the phonon scattering cross section of polydispersed spherical nanoparticles. Using perturbation of the Hamiltonian due to differences in mass and bond stiffness between a host medium and a spherical nanoparticle, an analytical solution is obtained for the scattering cross section in the Rayleigh limit when the size parameter approaches zero. In the geometrical scattering limit, when the size parameter approaches infinity, the van de Hulst approximation for anomalous diffraction is used to estimate the scattering cross section as a function of acoustic impedance mismatch between the host medium and the spherical nanoparticle. Finally, these two limiting cases are bridged by a simple expression to estimate the scattering cross section for intermediate values of the size parameter. Using this, the scattering cross section for a polydispersed distribution of spherical nanoparticles was also estimated as a function of the parameters defining the statistical size distribution.
A Study of the Mean Southerly Wind-Maximum in Low Levels Associated with a Period of Summer Precipitation in the Middle West (1954)

A low-level jet in southerly winds is described making use of a mean cross-section for a 48-hour period when the pattern was nearly stationary. The period is that of heavy rains in Kansas which were associated with the Kaw (Kansas) River and Kansas City floods in July, 1951. Most of the moisture carried into the area of heavy precipitation, was transported in the low-level jet.
Urine High-Sensitivity Troponin I Predict Incident Cardiovascular Events in Patients with Diabetes Mellitus (2020)

In patients with diabetes mellitus (DM), incident cardiovascular (CV) events are associated with poor long-term outcomes. Serum high-sensitivity troponin I (hs-TnI) is widely used to diagnose and predict outcomes in patients with acute coronary syndrome, however, few studies have investigated the accuracy of urine hs-TnI as a predictor for incident CV events in patients with DM. The enrolled participants included patients with DM. Fresh urine hs-TnI levels were measured. Medical records of enrolled patients were used to determine the number of incident CV events prospectively for 3 months. The study cohort comprised 378 participants. We observed significantly higher levels of urine hs-TnI in those with than without subsequent incident CV events. The multivariate logistic regression analysis using different models consistently showed that urine hs-TnI > 4.10 pg/mL was an independent factor predictive of incident CV events. The ROC-AUC analysis revealed that the optimal cutoff value for urine hs-TnI for predicting incident CV events was 1.55 pg/mL and the area was 0.611 (<i>p</i> = 0.027). A single measurement of urinary hs-TnI, collected easily and non-invasively, may be an acceptable biomarker for predicting subsequent incident CV events in patients with DM.
Teledentistry: An Appraisal of Google Play Store Applications (2023)

Abstract Objectives M-health technology facilitates and equips us with the required medical-related information and knowledge. This research work aims to provide an overview of m-health apps related to dentistry on the Google Play Store. Materials and Methods This widely used official smartphone platform was screened for the most widely available apps by putting the Medical Subject Headings (MeSH) and keywords “teledentistry, dentistry, and dental” and the resultant apps were evaluated for the number of downloads, ratings, release date, and number of reviews. Results The apps were categorized depending upon their applicability into different subgroups, which include patient education apps, dentist appointment apps, kid's apps, undergraduate apps, graduates and general dentist apps, postgraduate dentist apps, commercial and social networking apps, and other miscellaneous apps. The engagement of the users was evaluated in all the categories and the applicability of apps in respective categories was evaluated. The study concluded that despite plentiful apps in each category, the engagement of individuals with the m-health apps related to dentistry is relatively low. However, few creative apps in each category showed bright prospects for productivity and engagement. Conclusion Centralization and appropriately supervised apps with quality information by some official health care platforms can enhance the effectiveness and prepare this platform for the future of dentistry in the world of semantic web and blockchain.
Selective host–guest interaction of single-walled carbon nanotubes with functionalised fullerenes (2004)

Exohedrally functionalised fullerenes have been inserted in single-walled carbon nanotubes (SWNTs) with the aid of supercritical carbon dioxide to form peapods; C(61)(COOEt)(2) are encapsulated in SWNTs in high yield, whereas C(61)(COOH)(2) aggregate via hydrogen bonding to form a supramolecular complex, which sterically hinders encapsulation and causes it to adhere to the exterior surface of the SWNTs.