gebhart/patrepeval huggingface dataset:
Constrained Layer Damping of Initially Stressed Composite Beams Using Finite Elements (1992)

This paper presents the development of an efficient finite element model for the analysis of laminated composite beams treated by a constrained viscoelastic layer. The formulation presented includes the ability to model a structure about preloaded con figurations. Since most of the damping ability is due to the shearing of the viscoelastic layer, the model is designed to represent this aspect accurately. An offset beam, shear- deformable element, which is specially suited for modeling such laminated beams is pre sented. The viscoelastic layer is modeled by using two-dimensional plane finite elements which are compatible with the beam elements. In case of a structure with initial load, the final equations are linearized so that first increment of motion, the part due to the initial load is linear, and the second, the part due to the dynamic load is linearized. System damping and tip displacement are compared with existing approximate results and experi mental data whenever possible. Results confirm that dynamic response is substantially im proved by use of such damping treatments, and give some useful information regarding de signing a structure for high damping using constrained damping treatments.
Direct molecular weight determination of resin‐bound oligopeptides using 252 Cf plasma‐desorption mass spectrometry (1991)

Plasma-desorption mass spectrometry is proved to be capable of the direct molecular weight determination of totally protected resin-bound oligopeptides. The molecular weight measured is the molecular weight of the fully protected oligopeptide including the molecular weight of the linker, which connects the oligopeptide and the polystyrene resin. This method makes it possible to check the success of (a step in) the synthesis of a peptide before its deprotection or cleaving from the resin. This can make it a strong tool in the analysis of resin-bound oligopeptides.
Trends in low power low voltage d.c./d.c. converters (2000)

New integrated circuits are demanding very low supply voltages (1.5 V, 1.2 V, ...) with a very high quality. Low supply voltages allow for reducing the power consumption and increasing the integration density as well as the operation speed of the integrated circuits. Powering properly these new electronics loads is not a trivial question at all. New dynamic response specifications affect dramatically the design of the power supply. Topology selection does not depend only on size and efficiency considerations but also on its dynamic response.Size, efficiency and dynamic response are strongly related (Fig. 1). Critical issues in the design of low voltage power sup-plies are the topology selection, switching frequency, efficiency, dynamic response, packaging, input voltage, transformer design, etc. Design of these new power supplies is very complex, and all these aspects should be considered together Design of the transformer becomes very critical when auxiliary windings are needed to drive the Synchronous Rectifiers. Modern technologies are necessary to couple properly all the windings.Topologies used in the last years to supply low voltage circuits (forward with active clamp, half bridge with complementary control) are not the best option now, because their dynamic response is not good enough to supply properly the new loads.Topologies that drive symmetrically the transformer (classical half bridge, push pull) are a better option, but new techniques to implement self-driven synchronous rectification are necessary. Two possible solutions for powering the new IC are analyzed in this paper, and validated with experimental results.
Characterization of inflammatory mediator release from purified human lung mast cells. (1986)

The release of inflammatory mediators (histamine, PGD2, TxB2, and LTC4) from purified human lung mast cells was characterized by kinetic and anti-IgE dose-response parameters. The relative rate of mediator release was histamine greater than PGD2 = TxB2 greater than LTC4, with one half maximal release occurring at approximately 2, 5, and 10 min, respectively. In 2 experiments, stimulation with anti-IgE caused significant quantities of platelet-activating factor (PAF) to appear rapidly (2 min) in the cell pellet; cell-associated PAF declined to low levels by 45 min. The optimal concentration of anti-IgE for the release of the arachidonate cyclooxygenase metabolites PGD2 and TxB2 (0.3 microgram/ml) was 10- to 30-fold less than that required for the release of histamine and LTC4 (3 to 10 micrograms/ml), suggesting that these release processes may have differential IgE Fc receptor cross-linking requirements. At optimal histamine release, the magnitude of the release of each arachidonate metabolite was found to correspond to the magnitude of histamine release, however, suggesting that the 2 processes are linked either in series or in parallel.
A Knowledge-Based Method for Innovative Design for Additive Manufacturing Supported by Modular Ontologies (2018)

Additive manufacturing (AM) offers significant opportunities for product innovation in many fields provided that designers are able to recognize the potential values of AM in a given product development process. However, this may be challenging for design teams without substantial experience with the technology. Design inspiration based on past successful applications of AM may facilitate application of AM even in relatively inexperienced teams. While designs for additive manufacturing (DFAM) methods have experimented with reuse of past knowledge, they may not be sufficient to fully realize AM's innovative potential. In many instances, relevant knowledge may be hard to find, lack context, or simply unavailable. This design information is also typically divorced from the underlying logic of a products' business case. In this paper, we present a knowledge based method for AM design ideation as well as the development of a suite of modular, highly formal ontologies to capture information about innovative uses of AM. This underlying information model, the innovative capabilities of additive manufacturing (ICAM) ontology, aims to facilitate innovative use of AM by connecting a repository of a business and technical knowledge relating to past AM products with a collection of knowledge bases detailing the capabilities of various AM processes and machines. Two case studies are used to explore how this linked knowledge can be queried in the context of a new design problem to identify highly relevant examples of existing products that leveraged AM capabilities to solve similar design problems.
Organic energy devices from ionic liquids and conducting polymers (2016)

The interaction of ionic liquids and conducting polymers were studied, and organic electronic devices fabricated using this new insight.
[Posterior guidance of the mandible as a neuromuscular assigned dimeric joint chain]. (1991)

Measurements of the mandible's movements which take its six degrees of freedom into account show that the conventional concept of a condylar hinge axis does not hold: on principle the structure of motion of the condylar hinge axis is not different from that of the incisal edge. The spaces of movement which are related to the condylar hinge axis and the incisal edge are factually enforced by a hinge axis of the neuromuscular system. This neuromuscular hinge axis cannot directly be related to anatomical structures although in the sagittal-vertical plane it reduces the number of the degrees of freedom from three to two.
Switching of Sox9 expression during musculoskeletal system development (2020)

The musculoskeletal system, which comprises muscles, tendons, and bones, is an efficient tissue complex that coordinates body movement and maintains structural stability. The process of its construction into a single functional and complex organization is unclear. SRY-box containing gene 9 (Sox9) is expressed initially in pluripotent cells and subsequently in ectodermal, endodermal, and mesodermal derivatives. This study investigated how Sox9 controls the development of each component of the musculoskeletal system. Sox9 was expressed in MTJ, tendon, and bone progenitor cells at E13 and in bone at E16. We detected Sox9 expression in muscle progenitor cells using double-transgenic mice and myoblastic cell lines. However, we found no Sox9 expression in developed muscle. A decrease in Sox9 expression in muscle-associated connective tissues, tendons, and bones led to hypoplasia of the cartilage and its attachment to tendons and muscle. These results showed that switching on Sox9 expression in each component (muscle, tendon, and bone) is essential for the development of the musculoskeletal system. Sox9 is expressed in not only tendon and bone progenitor cells but also muscle progenitor cells, and it controls musculoskeletal system development.
Fabrication and Characterization of Planar Plasmonic Substrates with High Fluorescence Enhancement (2010)

The use of plasmonic nanostructures for fluorescence signal amplification is currently a very active research field. The detection of submonolayers of proteins labeled with organic dyes is a widely used technique in surface-based immunoassays and DNA hybridization. There is a strong interest in the development of new optical and chemical methods to increase the signal from ultralow concentrations of dyes on the surface of sensor substrates. Herein, we have explored the possibility of using vacuum-deposited silver nanostructures on dielectric layers and silver mirrors as potential plasmonic substrates that effectively amplify fluorescence over a broad spectral range. By optimizing deposition parameters for dielectric layers and silver nanostructures and applying thermal annealing processes, we observed large fluorescence amplifications from three different dye-strept(avidin) conjugates: about 7-fold for a UV/blue dye AF350-Av, 49-fold for a blue-green dye AF488-SA, and up to 208-fold for red-emitting AF647-SA dye. The observed amplification factors for the ensemble of fluorophores are very promising for development of surface-based bioassays. These substrates can be prepared using simple vacuum deposition in which we circumvent using the expensive nanofabrication methods. In addition, unlike most nanofabrication methods, the present approach is appropriate for large scale fabrication of substrates with microscope slide surface area suitable for sensing applications.
Performance analysis of LDA, QDA and KNN algorithms in left-right limb movement classification from EEG data (2010)

Brain Computer Interface (BCI) improve the lifestyle of the normal people by enhancing their performance levels. It also provides a way of communication for the disabled people with their surrounding who are otherwise unable to physically communicate. BCI can be used to control computers, robots, prosthetic devices and other assistive technologies for rehabilitation. The dataset used for this study has been obtained from the BCI competition II 2003 databank provided by the University of Technology, Graz. After pre-processing of the signals from their electrodes (C3 & C4), the wavelet coefficients, Power Spectral Density of the alpha and the central beta band and the average power of the respective bands have been employed as features for classification. In one of the approaches we fed all the extracted features individually and in the other approach we considered all features together and submitted them to LDA, QDA and KNN algorithms distinctly to classify left and right limb movement. The aim of this study is to analyze the performance of linear discriminant analysis (LDA), quadratic discriminant analysis (QDA) and K-nearest neighbor (KNN) algorithms in differentiating the raw EEG data obtained, into their associative movement, namely, left-right movement. Also the importance of the feature vectors selected is highlighted in this study. The total set to feature vector comprising all the features (i.e., wavelet coefficients, PSD and average band power estimate) performed better with the classifiers without much deviation in the classification accuracy, i.e., 80%, 80% and 75.71% with LDA, QDA and KNN respectively. Wavelet coefficients performed best with QDA classifier with an accuracy of 80%. PSD vector resulted in superior performance of 81.43% with both QDA and KNN. Average band power estimate vector showed highest accuracy of 84.29% with KNN algorithm. Our approach presented in this paper is quite simple, easy to execute and is validated robustly with a large dataset.
Toward a unified view of electronic commerce (1998)

article Free Access Share on Toward a unified view of electronic commerce Authors: Frederick J. Riggins Georgia Institute of Technology, Atlanta Georgia Institute of Technology, AtlantaView Profile , Hyeun-Suk (Sue) Rhee Georgia Institute of Technology, Atlanta Georgia Institute of Technology, AtlantaView Profile Authors Info & Claims Communications of the ACMVolume 41Issue 10Oct. 1998pp 88–95https://doi.org/10.1145/286238.286252Published:01 October 1998Publication History 97citation2,735DownloadsMetricsTotal Citations97Total Downloads2,735Last 12 Months190Last 6 weeks12 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
The Perioperative Management of a Patient with Complex Single Ventricle Physiology and Pheochromocytoma (2005)

Pheochromocytoma is associated with intense physiologic effects of alpha- and beta-adrenergic stimulation from catecholamine secretion. Perioperative management for these patients includes alpha-adrenergic receptor blockade, intravascular volume replacement, and, if necessary, beta-adrenergic receptor blockade. Significant perioperative changes in preload and afterload, fluid status, heart rate and rhythm, and inotropy can occur and may be contrary to anesthetic management goals for patients with certain conditions of congenital heart disease. We report the perioperative management with doxazosin of a patient with single ventricle physiology and cavo-pulmonary and aorto-pulmonary lung perfusion who presented for resection of a pheochromocytoma.
MQTT based Wi-Fi communication between Microcontroller and FPGA (2021)

This paper explains the design, implementation, and application of communication between Microcontroller and FPGA using MQTT protocol. While there has been similar communication between the Microcontroller and FPGA using Bluetooth and RF modules, Wi-Fi modules can establish a larger network for communication, have larger coverage, and higher speed. Embedded systems using both the FPGA and microcontrollers bind the devices to performing specific functionalities, such cross-platform communication is not common. The use of microcontrollers in embedded systems is common because they are user friendly and comparatively easy to program. FPGA however involve parallel programming, increasing design complexity while increasing processing speed. FPGA can be used as central processing unit that improves system performance and frees up microcontrollers from cycle intensive tasks. In this project, the MSP432 microcontroller and BASYS3 FPGA board are made to communicate by using a MQTT protocol. A mobile application which acts as a MQTT. broker (server) is initialized at certain static IP address. The Wi-Fi module connected to the MSP432 generates an Access Point to which the Wi-Fi module at BASYS3 and the mobile phones connect to. This establishes a wireless network between the three devices. Messages are then exchanged using UART communication which sends or receives characters on pressing the onboard pushbuttons. Bidirectional messages are sent or received based on the publisher/subscriber mode of BASYS3 and MSP432 board.
Advantages of Slewing an Active Structure (1990)

The slewing control of an active flexible structure is considered by examin ing the equations of motion of an integrated actuator/structure system containing both the actuator and structure dynamics. These equations are derived using a Hamiltonian ap proach. The system under consideration is a slewing flexible structure, a thin aluminum beam, torque driven by an armature controlled DC electric motor and actuated by a piece- wise distributed piezoceramic actuator. An improvement in performance is gained by 1) including the effects of motor actuator and beam dynamic interaction and 2) using a piezo electric device, layered on the structure, for direct vibration suppression of the structural dynamics. A comparison is made using simulations, to point out the advantages of slewing an active structure versus slewing a passive structure. This presents a multi input slewing control problem which is implemented using a standard linear quadratic regulator control design.
Tritium recovery and separation from CTR plasma exhausts and secondary containment atmospheres (1974)

Pecent experimental successes have generated increased interest in the development of thermonuclear reactors as power sources for the future.This paper examines tritium containment problems posed by an operating CTR and sets forth some:processing, schemes currently being evaluated at the Oak Ridge National laboratory.An appreciation of the CTR tri.trum management problem can best be realized by recalling that : i tritium production rates for various fission reactors range from 2 x 10* to 9 x ISfi Ci/yr per 1000 MW(e).Present estimates of tritium production in a CTR blanket exceed 10 9 Ci/yr.for t>xe same level of power generation, and tritiuia process systems may handle 10 4 to 20 times that amount.V :Tritixun's high permeability through most materials: of construction at * high temperatures makes secondary contaixaaent mandatory for most piping. Processing of_these containment atmospheres will probably involve conversion .. M of the tritium to a nonpermeating form (T s 0) followed by trapping on con-.' ?venticnal beds of desiccant material.In a similar fashion, all purge streams ;| and process fluid vent gases will be subjcv-ud.lo tritium recovery prior to tmospheric release.c:. --1|Two tritium process systems'will be required, one to recover tritium .,^| produced by breeding in the blanket and another to recover uriburned tritium .'f in the plasma exhaust.Plasma exhaust processing will be unconventional since ;| the exhaust gas pressure will lie between lO" 3 and 10~9 torr.Treatment of 'I this gas strea-m will entail the removal of small quantities of protiuo and ~| from p i much larger deuterium-tritium mixture which will be recycled.j|
Synthesis of carbon‐14 labeled CI‐926 and CI‐927, new antihypertensives (1987)

Abstract 3‐[4‐]4‐(3‐Methylphenyl)‐1‐piperazinyl[butyl]‐2,4‐imidazolinedione, CI‐926 ( 1 ), and 3‐[4‐4‐(3‐ethoxyphenyl)‐1‐piperazinyl]butylamino‐5,5‐dimethyl‐2‐cyclohexen‐1‐one, CI‐927 ( 2 ) are new antihypertensive agents which have been carbon‐14 labeled in three steps starting from ethylene‐ 14 C 2 oxide ( 5 ). The overall radiochemical yields for 1 and 2 were 69% and 66% respectively. The specific activity for both compounds was initially 22.6 mCi/mmol before final dilution.
Squamous Cell Carcinoma Associated with Sarcoidosis in the Lung (1978)

A male patient, operated for squamous cell carcinoma of the lung, in whom sarcoidosis was discovered in the resected lung specimen, is reported. The increased association of sarcoidosis along with malignant diseases is discussed, as well as the various mechanisms probably responsible for this association.
Epidemiological analysis of pneumococcal strains isolated at Yangon Children’s Hospital in Myanmar via whole-genome sequencing-based methods (2021)

<i>Streptococcus pneumoniae</i> causes over one million deaths from lower respiratory infections per annum worldwide. Although mortality is very high in Southeast Asian countries, molecular epidemiological information remains unavailable for some countries. In this study, we report, for the first time, the whole-genome sequences and genetic profiles of pneumococcal strains isolated in Myanmar. We isolated 60 streptococcal strains from 300 children with acute respiratory infection at Yangon Children's Hospital in Myanmar. We obtained whole-genome sequences and identified the species, serotypes, sequence types, antimicrobial resistance (AMR) profiles, virulence factor profiles and pangenome structure using sequencing-based analysis. Average nucleotide identity analysis indicated that 58 strains were <i>S. pneumoniae</i> and the other 2 strains were <i>Streptococcus mitis</i>. The major serotype was 19F (11 strains), followed by 6E (6B genetic variant; 7 strains) and 15 other serotypes; 5 untypable strains were also detected. Multilocus sequence typing analysis revealed 39 different sequence types, including 11 novel ones. In addition, genetic profiling indicated that AMR genes and mutations spread among pneumococcal strains in Myanmar. A minimum inhibitory concentration assay indicated that several pneumococcal strains had acquired azithromycin and tetracycline resistance, whereas no strains were found to be resistant against levofloxacin and high-dose penicillin G. Phylogenetic and pangenome analysis showed various pneumococcal lineages and that the pneumococcal strains contain a rich and mobile gene pool, providing them with the ability to adapt to selective pressures. This molecular epidemiological information can help in tracking global infection and supporting AMR control in addition to public health interventions in Myanmar.
Innovative low cost fibre-reinforced concrete—Part I: Mechanical and durability properties (2012)

Adequate mechanical properties of concrete delay formation of cracks due to traffic load, temperature-induced thermal stresses, freeze-thaw damage, water infiltration, ageing effects, and so forth. With the progress of analysis, it became obvious that incorporation of rubber particles (5 percent of the total volume of aggregate) causes minimum reduction if correlation is done with the mixture containing the air entraining admixture only (Fig. 1).
From death receptor to reactive oxygen species and c‐Jun N‐terminal protein kinase: the receptor‐interacting protein 1 odyssey (2007)

Death receptors (DRs) are more than simple killers: they control cell growth, proliferation, and survival, thereby playing a pivotal role in immune and inflammatory responses. Some of these phenomena might be explained by aberrant reactive oxygen species (ROS) production and metabolism, which can lead to oxidative stress. A key signaling molecule of DR-initiated intracellular pathways, receptor-interacting protein 1 (RIP1), orchestrates a complex control of multiple responses and may link DR-associated signaling complexes to ROS production by mitochondria. Yet, RIP1 is also an important regulator of endogenous anti-oxidants and ROS scavenging enzymes, because it is required for nuclear factor kappaB activation that results in expression of anti-apoptotic and anti-oxidant proteins. Alteration of RIP1 function may result in ROS accumulation and abnormal c-Jun N-terminal protein kinase activation, affecting inflammatory responses, innate immunity, stress responses, and cell survival. These molecular mechanisms may be involved in neoplastic, autoimmune, neurodegenerative, inflammatory, and metabolic diseases.