gebhart/patrepeval huggingface dataset:
Interacting mobile IP and SIP for efficient mobility support in all IP wireless networks (2004)

Next-generation mobility support can be achieved by jointly applying mobile IP (MIP) and the session initiation protocol (SIP) in all IP wireless networks. Though a full integration of both protocols proves to be most cost-effective in the long run, a prompt deployment necessitates an efficient hybrid MIP-SIP architecture for the current stage where MIP and SIP coexist separately. Traditional hybrid MIP-SIP schemes operate MIP and SIP independently, which result in significant redundant costs. This paper investigates interactions between MIP and SIP to maximise their complementary powers for more efficient mobility support while keeping their physical entities intact. The desired interactions are identified in mobility procedures including location update, session setup and handoff. Two different schemes are proposed to establish such interactions. The analysis demonstrates that both schemes outperform traditional hybrid MIP-SIP schemes in terms of lower handoff delay and lower signalling overhead. The proposed schemes are applicable to both MIPv4 and MIPv6, though MIPv6 is emphasised.
Caecal Rupture in Psychotic Patients (1974)

Simple Oxygen-failure Safety Device SIR,-I was concerned to note that the oxygen-failure safety device reported by Drs.H
Messung der Bioimpedanz bei Dialysepatienten zur Bestimmung der Wassermenge in den einzelnen Flüssigkeitsräumen des Körpers (2009)

Article Messung der Bioimpedanz bei Dialysepatienten zur Bestimmung der Wassermenge in den einzelnen Flüssigkeitsräumen des Körpers was published on January 1, 1998 in the journal Biomedical Engineering / Biomedizinische Technik (volume 43, issue s1).
Total knee arthroplasty in severe haemophilic patients under continuous infusion of clotting factors (2011)

Therapeutic study, Level IV.
A Simple Reverse Transcriptase PCR Melting-Temperature Assay To Rapidly Screen for Widely Circulating SARS-CoV-2 Variants (2021)

The increased transmission of SARS-CoV-2 variants of concern (VOC), which originated in the United Kingdom (B.1.1.7/alpha), South Africa (B1.351/beta), Brazil (P.1/gamma), the United States (B.1.427/429 or epsilon), and India (B.1.617.2/delta), requires a vigorous public health response, including real-time strain surveillance on a global scale. Although genome sequencing is the gold standard for identifying these VOCs, it is time-consuming and expensive. Here, we describe a simple, rapid, and high-throughput reverse transcriptase PCR (RT-PCR) melting-temperature (<i>T<sub>m</sub></i>) screening assay that identifies the first three major VOCs. RT-PCR primers and four sloppy molecular beacon (SMB) probes were designed to amplify and detect the SARS-CoV-2 N501Y (A23063T) and E484K (G23012A) mutations and their corresponding wild-type sequences. After RT-PCR, the VOCs were identified by a characteristic <i>T<sub>m</sub></i> of each SMB. Assay optimization and testing was performed with RNA from SARS-CoV-2 USA WA1/2020 (wild type [WT]), B.1.1.7, and B.1.351 variant strains. The assay was then validated using clinical samples. The limit of detection for both the WT and variants was 4 and 10 genomic copies/reaction for the 501- and 484-codon assays, respectively. The assay was 100% sensitive and 100% specific for identifying the N501Y and E484K mutations in cultured virus and in clinical samples, as confirmed by Sanger sequencing. We have developed an RT-PCR melt screening test for the major VOCs that can be used to rapidly screen large numbers of patient samples, providing an early warning for the emergence of these variants and a simple way to track their spread.
Begleitverletzungen bei distaler Radiusfraktur (2013)

Verletzungen des distalen Radius mit Verkürzung und Verkippung führen nicht selten zu einer Mitverletzung von stabilisierenden Bandstrukturen – insbesondere des Discus triangularis (TFC) und des skapholunären Bandes. Neben diesen begleitenden Weichteilverletzungen dürfen Frakturen der Handwurzelknochen nicht übersehen werden. Gerade der jüngere Patient, dessen Frakturursache meist auf einer hohen Krafteinwirkung beruht, ist da gefährdet, und es muss auf eine Skaphoidfraktur oder eine, als Maximalvariante, Fraktur in Kombination mit Luxation geachtet werden. Eine ausbleibende bzw. verspätete Versorgung dieser Begleitverletzungen führt zu funktionellen Defiziten. Diese Verletzungen erfordern häufig eine differenzierte klinische, radiologische oder arthroskopische Diagnostik. Neben einer möglichst anatomischen Wiederherstellung des distalen Radius müssen daher die Verletzungen des distalen Radioulnargelenks (DRUG), des Discus triangularis (TFC) und der wichtigen Band- bzw. Knochenstrukturen beachtet werden. Das funktionelle Ergebnis ergibt sich daher aus der anatomischen Wiederherstellung des distalen Radius einschließlich seiner unmittelbaren Begleitstrukturen.
A Highly Specific and Sensitive Radioimmunoassay of Caerulein, An Analogue of Cholecystokinin-8 (1988)

Abstract A highly specific and sensitive competitive radioimmunoassay was developed for caerulein (CLN), an analogue of cholecystokinin-8 (CCK-8), in plasma and brain. Antiserum was produced in rabbit by immunization with Nδ-[CLN-(1-6)]-ornithine amide conjugated with bovine serum albumin by the glutaraldehyde method. Nα-[CLN-(1-6)]-lysine amide was labelled with 125I-Bolton & Hunter reagent and used as a labelled antigen after purification by high-performance liquid chromerography. This assay was highly specific for CLN, and cross reactivities for other related peptides, CCK-4, CCK-8, gastrin-I, and gastrin-(14–17), were not observed (<0.01%). The limits of determination in biological specimens after CLN administration were 11 pg/ml in human plasma and rat plasma and 80 pg/g in rat brain. This study showed that the slight structure difference between hapten and 125I-labelled antigen is important to the assay performance.
First record of Lingulodinium polyedrum (Dinophyceae) resting cysts in coastal sediments from the Inner Sea of Chiloé, Los Lagos Region, southern Chile (~41°-43°S) (2011)

Quistes de resistencia del dinoflagelado potencialmente toxico Lingulodinium polyedrum (Stein) Dodge son registrados por primera vez en sedimentos costeros del Mar Interior de Chiloe. Se entrega informacion de abundancia, distribucion, descripcion y fotomicrografias de la especie. Se confirma la presencia de L. polyedrum en aguas costeras del sur de Chile.
A novel mellitin‐derived peptide nanoparticle delivery system for STAT3 siRNA mediated killing of B16 melanoma cells (2012)

Exogenously delivered siRNA has the potential to form a new class of cancer therapeutics based on sequence specific silencing of oncogene expression. Previous work has shown that the transcription factor, Signal Transducer and Activator of Transcription 3 (STAT3), is constitutively activated in the B16 melanoma cell line and mediates resistance to apoptosis by driving expression of anti‐apoptotic genes. In this study, we sought to establish the efficacy of novel peptide‐based siRNA delivery agents derived from the bee‐venom component, melittin, for STAT3 knockdown in B16 cells. Modifications to melittin (GIGAVLKVLTTGLPALISWIKRKRQQ) include truncation of its N‐terminus to reduce cytotoxicity and addition of basic residues to its C‐terminus to improve electrostatic binding to siRNA. The resulting peptide, p5RHH (VLTTGLPALISWIRRRHRRHC), complexes siRNA to form a nanoparticle delivery system, and mediates sequence specific knockdown of GFP in B16‐GFP cells. Confocal microscopy reveals that Cy3 labeled oligonucleotides are taken up by cells with diffuse cytoplasmic staining after 2 hours. Notably, p5RHH‐mediated transfection of 50nM STAT3 siRNA reduces B16 viability by 25% without vector associated cytotoxicity. These results indicate that p5RHH is a high efficiency, low toxicity siRNA transfection agent with implications for cancer therapy. Supported by Sigma‐Aldrich Predoctoral Fellowship.
ChemInform Abstract: NUCLEOPHILIC ADDITION OF THIOLS TO ACETYLENES IN LIQUID AMMONIA (1983)

Abstract Während Acetylen selbst in flüssigem Ammoniak nicht mit Thiolen (II) reagiert, addieren monosubstituierte Acetylene (Ia)‐(Id) mit Elektronenakzeptor‐Gruppen ohne Katalysator in Abhängigkeit von den aktivierenden Gruppen l ‐ 2 Moleküle (II).
Blocking of targeted microRNAs from next-generation sequencing libraries (2015)

Highly abundant microRNAs (miRNAs) in small RNA sequencing libraries make it difficult to obtain efficient measurements of more lowly expressed species. We present a new method that allows for the selective blocking of specific, abundant miRNAs during preparation of sequencing libraries. This technique is specific with little off-target effects and has no impact on the reproducibility of the measurement of non-targeted species. In human plasma samples, we demonstrate that blocking of highly abundant hsa-miR-16-5p leads to improved detection of lowly expressed miRNAs and more precise measurement of differential expression overall. Furthermore, we establish the ability to target a second abundant miRNA and to multiplex the blocking of two miRNAs simultaneously. For small RNA sequencing, this technique could fill a similar role as do ribosomal or globin removal technologies in messenger RNA sequencing.
Memory system support for image processing (2003)

Image processing applications tend to access their data non-sequentially and reuse that data infrequently. As a result, they tend to perform poorly on conventional memory systems due to high cache and TLB miss rates and are particularly sensitive to the growing latency of main memory. We analyze the memory performance of three image processing algorithms (volume rendering, image warping and image filtering) on both a conventional memory system and on the Impulse memory system. The Impulse memory system allows application software to control how, when, and where data are loaded into a conventional processor cache. It does this by letting software configure how the memory controller interprets the physical addresses exported by the processor, which enables an application to dynamically change how data are fetched. Sparse data can be accessed densely, which improves both cache and TLB utilization, and memory latency is hidden by prefetching data within the memory controller. We find that for these image processing codes, using an Impulse memory system yields speedups of 40% to 226% over an otherwise identical machine with a conventional memory system.
New strategies for addressing the diversity–validity dilemma with big data. (2023)

The diversity-validity dilemma is one of the enduring challenges in personnel selection. Technological advances and new techniques for analyzing data within the fields of machine learning and industrial organizational psychology, however, are opening up innovative ways of addressing this dilemma. Given these rapid advances, we first present a framework unifying analytical methods commonly used in these two fields to reduce group differences. We then propose and demonstrate the effectiveness of two approaches for reducing group differences while maintaining validity, which are highly applicable to numerous big data scenarios: iterative predictor removal and multipenalty optimization. Iterative predictor removal is a technique where predictors are removed from the data set if they simultaneously contribute to higher group differences and lower predictive validity. Multipenalty optimization is a new analytical technique that models the diversity-validity trade-off by adding a group difference penalty to the model optimization. Both techniques were tested on a field sample of asynchronous video interviews. Although both techniques effectively decreased group differences while maintaining predictive validity, multipenalty optimization outperformed iterative predictor removal. Strengths and weaknesses of these two analytical techniques are also discussed along with future research directions. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
Poly(ethylene glycol)-block-poly(N-vinylformamide) Copolymers Synthesized by the RAFT Methodology (2003)

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTPoly(ethylene glycol)-block-poly(N-vinylformamide) Copolymers Synthesized by the RAFT MethodologyLianjun Shi, Toby M. Chapman, and Eric J. BeckmanView Author Information Department of Chemical and Petroleum Engineering and Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15261 Cite this: Macromolecules 2003, 36, 7, 2563–2567Publication Date (Web):March 11, 2003Publication History Received12 September 2002Revised20 January 2003Published online11 March 2003Published inissue 1 April 2003https://pubs.acs.org/doi/10.1021/ma025670zhttps://doi.org/10.1021/ma025670zbrief-reportACS PublicationsCopyright © 2003 American Chemical SocietyRequest reuse permissionsArticle Views2890Altmetric-Citations79LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Copolymerization,Copolymers,Monomers,Radical polymerization,RAFT polymerization Get e-Alerts
Compounding of MWCNTs with PS in a Twin‐Screw Extruder with Varying Process Parameters: Morphology, Interfacial Behavior, Thermal Stability, Rheology, and Volume Resistivity (2012)

Abstract 1, 2, 3, 5, and 7.5 wt% MWCNTs are incorporated into PS in a twin‐screw extruder at varying speeds, throughputs and extruder barrel temperatures. Increased SME at enhanced processing speeds seems to have the single largest effect in enhancing dispersion. A relative evaluation of PS/MWCNT interactions indicate an interfacial layer growth of 24% for 2 wt% MWCNT at 1100 rpm compared to 18% growth at 500 rpm. Raman analysis does not show an MWCNT peak shift but a constant increase in FWHM is observed irrespective of the MWCNT content. A significant enhancement of thermal stability occurs up to 2 wt% MWCNT loading while 1–2 wt% shows the rheological threshold. The volume resistivity decreases dramatically in a 2 wt% sample processed at 1100 rpm compared to those processed at 500 rpm. magnified image
Root-to-shoot Translocation of Alkaloids is Dominantly Suppressed in Nicotiana alata (2012)

In tobacco (Nicotiana tabacum), nicotine and related pyridine alkaloids are produced in the root, and then transported to the aerial parts where these toxic chemicals function as part of chemical defense against insect herbivory. Although a few tobacco transporters have been recently reported to take up nicotine into the vacuole from the cytoplasm or into the cytoplasm from the apoplast, it is not known how the long-range translocation of tobacco alkaloids between organs is controlled. Nicotiana langsdorffii and N. alata are closely related species of diploid Nicotiana section Alatae, but the latter does not accumulate tobacco alkaloids in the leaf. We show here that N. alata does synthesize alkaloids in the root, but lacks the capacity to mobilize the root-borne alkaloids to the aerial parts. Interspecific grafting experiments between N. alata and N. langsdorffii indicate that roots of N. alata are unable to translocate alkaloids to their shoot system. Interestingly, genetic studies involving interspecific hybrids between N. alata and N. langsdorffii and their self-crossed or back-crossed progeny showed that the non-translocation phenotype is dominant over the translocation phenotype. These results indicate that a mechanism to retain tobacco alkaloids within the root organ has evolved in N. alata, which may represent an interesting strategy to control the distribution of secondary products within a whole plant.
The National Kidney Registry: transplant chains--beyond paired kidney donation. (2009)

The National Kidney Registry (NKR) has facilitated more than 100 transplants at 24 centers in the past 2 years and the numbers are rapidly increasing. The NKR has inherent capability for rapid change as innovations are developed and incorporated in the approach to matching donors and recipients in transplant chains. Kidneys are shipped with geotracking devices utilizing existing OPO procedures whenever patients are willing to accept them. This reduces the need for donor travel and increases the geographic area where matches can be made. Out-of-sequence transplants can be performed to improve logistics. Matching software is designed to facilitate chain transplantation and incorporates metrics that help transplant centers develop strategies to improve the chances that their patients can be transplanted. Daily match runs and close attention to repairing broken chains have been critical to growing the number of transplants that can be facilitated. A number of new innovations are expected to increase the opportunities for patients and their potential living donors.
Processing Time Aware Resource Allocation in Software Defined RANs (2019)

Computational elasticity concepts represent a quite promising area when it comes to virtualization and cloudification of radio access networks (C-RAN), especially within the context of 5G network architectures. The intention of such concepts is the provision of graceful degradation of quality of service (QoS) metrics under circumstances of scarcity of computational resources in virtualized networks. In this paper, we propose a new dynamic resource allocation strategy for the air interface that takes into account the computational resource utilization of virtualized network functions (VNFs) within the downlink transmission chain in terms of processing time requirements. The viability of the proposed concept is confirmed by an exemplary performance study addressing a typical deployment scenario within a software defined radio access network (SD-RAN).
Plerixafor is safe and efficacious for mobilization of peripheral blood stem cells in pediatric patients (2016)

Our findings suggest that plerixafor use in children is safe and efficacious for the mobilization of autologous PBSCs in subjects with relapsed malignancies or requiring stem cells for multiple transplants.
The pathology and mineral content of lungs in cases of mesothelioma in the United Kingdom in 1976. (1980)

A study was made of 93 cases of mesothelioma who died in 1976 in the United Kingdom. Lung tissue was available for mineral fibre analysis from 86 of these cases, and also from 29 cases of cerebrovascular disease and 27 cases of bronchial carcinoma, matched for place of death, age and sex with the mesothelioma cases. It was observed that: (1) mesothelioma patients had more amphibole fibres in their lungs than did control cases; (2) chrysotile fibres were not present in greater numbers in the mesothelioma patients than in the control cases; (3) four of the mesothelioma cases had no amphibole fibres in their lungs; two of these had chrysotile fibres, and the other two had no asbestos fibres; and (4) 30 cases of mesothelioma had no chrysotile fibres in their lungs.
Performance of FOC IM drive in SVM controlled five-level diode-clamped inverter (2012)

Multilevel inverters provide cost-effective solution in the medium voltage energy market. These converters synthesize the output voltage waveform from several steps of dc input source which approaches to sinusoidal waveform and minimizes the harmonic distortions. This paper discusses the features of 5-level diode-clamped inverter. The application of diode clamped multilevel inverter in Field-Oriented-Control (FOC) scheme of induction motor drive using space vector control scheme is explained. The performance of the scheme is evaluated in terms of ripple contents in torque, speed and total harmonic distortion in the current drawn by the motor.
A nonverbal signal in voices of interview partners effectively predicts communication accommodation and social status perceptions. (1996)

Derivations from nonverbal communications accommodation theory are tested, and this knowledge is extended both theoretically and methodologically. Fast fourier transform and statistical analysis of a low-frequency nonverbal signal-in voices from 25 dyadic interviews between a talk show host and his guests revealed voice convergence between partners. Correlation coefficients from comparisons of partners' voice spectra and factor analysis of the correlation matrix showed that lower status partners accommodated their voices to higher status partners via the nonverbal signal. Student ratings of the social status of the same talk show host and guests were correlated with factor loadings, thereby providing convergent validity of the nonverbal signal as a predictor of social status perceptions and accommodation.
MicroRNA profiling of rats with ochratoxin A nephrotoxicity (2014)

The abrogation of miRNA maturation process suggests a new target of OTA toxicity. Moreover, the identification of the differentially expressed miRNAs provides us a molecular insight into the nephrtoxicity of OTA.
Act Globally, Think Locally: Systems Biology Addresses the PDZ Domain (2010)

ADVERTISEMENT RETURN TO ISSUEPREVAddition, Retraction...Addition, Retraction, CorrectionORIGINAL ARTICLEThis notice is a correctionAct Globally, Think Locally: Systems Biology Addresses the PDZ DomainMark R. SpallerCite this: ACS Chem. Biol. 2010, 5, 7, 713Publication Date (Web):June 17, 2010Publication History Received4 June 2010Published online17 June 2010Published inissue 16 July 2010https://pubs.acs.org/doi/10.1021/cb100162shttps://doi.org/10.1021/cb100162scorrectionACS PublicationsCopyright © 2010 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views723Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (47 KB) Get e-AlertscloseSUBJECTS:Genomics,Rodent models,Systems biology Get e-Alerts