gebhart/patrepeval huggingface dataset:
A Survey of Visualization Systems for Network Security (2011)

Security Visualization is a very young term. It expresses the idea that common visualization techniques have been designed for use cases that are not supportive of security-related data, demanding novel techniques fine tuned for the purpose of thorough analysis. Significant amount of work has been published in this area, but little work has been done to study this emerging visualization discipline. We offer a comprehensive review of network security visualization and provide a taxonomy in the form of five use-case classes encompassing nearly all recent works in this area. We outline the incorporated visualization techniques and data sources and provide an informative table to display our findings. From the analysis of these systems, we examine issues and concerns regarding network security visualization and provide guidelines and directions for future researchers and visual system developers.
LoadAtomizer: A locality and I/O load aware task scheduler for MapReduce (2012)

Data-intensive computing systems like MapReduce and Dryad have emerged as a framework for leveraging computing resources of a cluster. I/O bottlenecks need to be eased to improve performance in data-intensive computing systems. State-of-the-art frameworks for data-intensive computing have tackled the issue with a data locality based task scheduling policy. However, locality-aware scheduling does not always work good to mitigate I/O bottlenecks when different I/O characteristic jobs run concurrently. This paper presents LoadAtomizer, a locality and I/O load aware task scheduler for MapReduce. LoadAtomizer mitigates the I/O bottlenecks of a cluster with locality and I/O load aware map task assignment and storage selection. LoadAtomizer quickly assigns a slave a map task whose input data is stored in a lightly loaded storage and commands the slave to read the input data from the storage. LoadAtomizer maintains the load information of storages and the network with a topology-aware load tree. A topology-aware load tree enables LoadAtomizer to select quickly a lightly loaded storage that a slave can access through a lightly loaded network path. Experimental results demonstrated that our prototype of LoadAtomizer shortened completion time of multiple jobs by up to 18.6 %.
Photonic crystal heterostructure laser (2005)

High-Q photonic crystal heterostructure laser cavities were fabricated and characterized. Good agreement was obtained between the numerical predictions and the experimental lasing data.
Encoding movies and data in DNA storage (2016)

Focusing on error-correction methods and codes, a systems level design is presented for encoding movies and digital information in DNA storage. A source of data (e.g., movies, audio) is compressed, efficiently encoded with redundant information, modulated, and stored in multiple DNA oligonucleotide strands. The goal is to decode the source from the DNA reliably even in the presence of diverse errors introduced by DNA synthesis, PCR amplification, and DNA sequencing processes.
Human dermal mast cells contain and release tumor necrosis factor alpha, which induces endothelial leukocyte adhesion molecule 1. (1991)

Tumor necrosis factor alpha (TNF-alpha) is a proinflammatory cytokine that mediates endothelial leukocyte interactions by inducing expression of adhesion molecules. In this report, we demonstrate that human dermal mast cells contain sizeable stores of immunoreactive and biologically active TNF-alpha within granules, which can be released rapidly into the extracellular space upon degranulation. Among normal human dermal cells, mast cells are the predominant cell type that expresses both TNF-alpha protein and TNF-alpha mRNA. Moreover, induction of endothelial leukocyte adhesion molecule 1 expression is a direct consequence of release of mast cell-derived TNF-alpha. These findings establish a role for human mast cells as "gatekeepers" of the dermal microvasculature and indicate that mast cell products other than vasoactive amines influence endothelium in a proinflammatory fashion.
Nanoparticle Technology for the Production of Functional Materials (2005)

The nanoparticle technology, relating to the preparation, characterization, processing, and applications of nano-sized particles, plays an increasingly important role in the emerging nano-technology. Although the nanoparticles have many unique functional properties superior to the coarser particles, they also suffer from dispersion and stability problems because of their strong cohesiveness and high specific surface areas. To make the best use of nanoparticles and solve their application problems, the development of nanomaterial processing techniques is essential.New chemical synthesis methods for producing nano-sized oxides particles in the gas phase and producing biocompatible polymeric nano-composite particles in the solution phase were elucidated in the paper. In addition, mechanical breakdown method (e.g. nano-grinding) was briefly discussed. Furthermore, newly developed dry particle processing systems for making high performance nanocomposites as well as their applications in Fuel Cells, Drug Delivery Systems, and Cosmetics were introduced.
Abstract 11663: The Features of Hypertensive Heart Failure With Preserved Ejection Fraction Assessed by 3-Dimensional Speckle Tracking Echocardiography With Novel Software (2014)

Background: Left ventricular (LV) pressure overload causes hypertrophy (LVH), which leads to reduced LV relaxation and compliance and results in heat failure with preserved ejection fraction (HFpEF...
Anisotropy of Magnetoresistance in HoB12 (2017)

We present results of precision measurements of magnetoresistance of isotopically pure Ho 11 B12 at low temperatures 2 10 K in magnetic field up to 80 kOe of different orientation to the crystal axes. The data obtained revealed strong anisotropy of magnetoresistance and allowed us to reconstruct magnetic H-T phase diagrams for main crystallographic directions H [001], [110], and [111]. Analysis of magnetoresistance derivatives allowed to conclude in favor of two main magnetoresistance contributions. Among of them the negative quadratic component is attributed to charge carriers scattering on a magnetic clusters of Ho 3+ ions (4f component) and positive linear one may be explained in terms of scattering on a spin density waves (5d component).
SPAG17 Is Required for Male Germ Cell Differentiation and Fertility (2018)

<i>Spag17</i> encodes a protein present in the axoneme central pair complex of motile cilia and flagella. A mutation in this gene has been reported to be associated with infertility caused by defects in sperm motility. Here, we report that <i>Spag17</i> knockout mice are infertile because of a severe defect in spermatogenesis. The histological evaluation of testis sections from mutant mice revealed seminiferous tubules with spermatogenesis arrested at the spermatid stage and cell debris in the cauda epididymis. The few sperm collected from the cauda epididymis were immotile and displayed abnormal tail and head morphology. Immunofluorescence analysis of <i>Spag17</i> knockout germ cells showed spermatids with abnormally long manchette structures and morphological defects in the head. Electron microscopy showed altered manchette microtubules, reduced chromatin condensation, irregular nuclear shape, and detached acrosomes. Additionally, the transport of proteins (Pcdp1 and IFT20) along the manchette microtubules was disrupted in the knockout elongating spermatids. Our results show for the first time that <i>Spag17</i> is essential for normal manchette structure, protein transport, and formation of the sperm head and flagellum, in addition to its role in sperm motility.
Properties of Polycaprolactam Polyethyleneimine Graft Copolymers (1972)

Abstract Caprolactum has been grafted onto polyethyleneimine. The mechanical properties of the resulting polycaprolactam polyethyleneimine graft copolymers were studied as a function of the number average molecular weight in the polycaprolactam side chain and compared to those of linear nylon 6.
Effect of particle size on the ferroelectric behaviour of tetragonal and rhombohedral Pb(ZrxTi1-x)O3ceramics and powders (1995)

The effect of particle size on the structure and ferroelectric behaviour of PZT powders and ceramics with bulk tetragonal and rhombohedral compositions is reported. To our knowledge, this is the first report of particle size effects for the rhombohedral PZT composition. It is pointed out that, below a certain critical size, the formation of ferroelectric domains is not energetically favourable. As a result, the ferroelectric transition may be suppressed due to depolarization and/or elastic energy contributions.
YXQN Reduces Alzheimer’s Disease-Like Pathology and Cognitive Decline in APPswePS1dE9 Transgenic Mice (2017)

Alzheimer's disease (AD) is the world's most common form of dementia, in which aggregation of amyloid-β (Aβ) is the hallmark. Unfortunately, few medicines have succeeded to completely cure AD. Yangxue Qingnao (YXQN) is a Chinese traditional medicine, and its pharmacological effect is improving cerebral blood flow. In this study, we firstly demonstrated that YXQN reduced AD-like pathology and cognitive impairment in APPswePS1dE9 (APP/PS1) mice with 2 months administration. Our data showed that YXQN substantially ameliorated behavioral defects in 10-month old APP/PS1 mice using Morris Water Maze and Y-maze tests, in which the cognitive ability of YXQN high-dose group approaches to wild type mice. Next, we focused on the brain pathological alterations in the YXQN group by three experiments, including thioflavin-S, congo-red, and Aβ-immunohistochemistry staining. The results demonstrated that the high-dose of YXQN dramatically suppressed amyloid plaques in the hippocampus and cortex of APP/PS1 mice, which showed a 47-72% reduction in plaque deposits, relative to the vehicle group. In addition, our data verified that YXQN decreased the cerebral amyloid load by attenuating β-secretase BACE1 and γ-secretase PS1 in the pathological processing of APP, and promoting the level of α-secretase ADAM10 in the physiological processing of APP to generate more sAPPα, which combats amyloidosis formation, and also carries out neurotropic and neuroprotective effect. Taken together, our results strongly suggest that YXQN could be a potential medicine for AD, and provide new evidence for further AD drug research and development.
ChemInform Abstract: Organometallics in Synthesis. Main Group Elements (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Conformational change of the coronavirus peplomer glycoprotein at pH 8.0 and 37 degrees C correlates with virus aggregation and virus-induced cell fusion (1990)

We have obtained biochemical and electron microscopic evidence of conformational changes at pH 8.0 and 37 degrees C in the coronavirus spike glycoprotein E2 (S). The importance of these changes is reflected in the loss of virus infectivity, the aggregation of virions, and increased virus-induced cell fusion at the same pH. Coronavirus (MHV-A59) infectivity is exquisitely sensitive to pH. The virus was quite stable at pH 6.0 and 37 degrees C (half-life, approximately 24 h) but was rapidly and irreversibly inactivated by brief treatment at pH 8.0 and 37 degrees C (half-life, approximately 30 min). Virions treated at pH 8.0 and 37 degrees C formed clumps and large aggregates. With virions treated at pH 8.0 and 37 degrees C, the amino-terminal peptide E2N (or S1) was released from virions and the remaining peptide, E2C (S2), was aggregated. Viral spikes isolated from detergent-treated virions also aggregated at pH 8.0 and 37 degrees C. Loss of virus infectivity and E2 (S) aggregation at pH 8.0 and 37 degrees C were markedly enhanced in the presence of dithiothreitol. On the basis of the effects of dithiothreitol on the reactions of the peplomer, we propose that release of E2N (S1) and aggregation of E2C (S2) may be triggered by rearrangement of intramolecular disulfide bonds. The aggregation of virions and the isolated E2 (S) glycoprotein at pH 8.0 and 37 degrees C or following treatment with guanidine and urea at pH 6.0 and 37 degrees C indicate that an irreversible conformational change has been induced in the peplomer glycoprotein by these conditions. It is interesting that coronavirus-induced cell fusion also occurred under mildly alkaline conditions and at 37 degrees C. Some enveloped viruses, including influenza viruses and alphaviruses, show conformational changes of spike glycoproteins at a low pH, which correlates with fusion and penetration of those viruses in acidified endocytic vesicles. For coronavirus MHV-A59, comparable conformational change of the spike glycoprotein E2 (S) and cell fusion occurred at a mildly alkaline condition, suggesting that coronavirus infection-penetration, like that of paramyxoviruses and lentiviruses, may occur at the plasma membrane, rather than within endocytic vesicles.
An Analysis of Cache Awareness for Interactive Selective Rendering (2008)

Interactive high-fidelity rendering is one of the major goals of computer graphics. Algorithms based on ray tracing are usually\nused to drive high-fidelity renderers. While ray tracing is often thought to be impractical for real time performance, recent\nalgorithmic advances in the field have led to the development of interactive ray tracers which leverage the performance of\nmodern parallel systems and cache awareness to obtain real-time rates for moderately complex scenes using Whitted-style ray\ntracing. Another method used for accelerating ray tracing is the use of selective rendering where only the pixels that need to be\ncomputed are traced and the remainder are computed by other means such as interpolation. The choice of which pixels to render\nmay depend on a number of factors, from simple ones that just compare the radiance values of the rays within a certain area and\nshoot further rays recursively if the difference in radiance is above a certain threshold, to more complex ones based on visual\nattention. Selective rendering algorithms may not be perfectly compatible with current interactive ray tracing techniques since\nselective rendering methods tend to be naturally incoherent, and the computation of rays at a stride may result in expensive\ncache misses. In this paper we analyse the effect of selective rendering on interactive ray tracing and hint at possible solutions\nthat would allow selective rendering to be compatible with interactive rendering methods to further improve rendering speeds.
Targeted Capture and Heterologous Expression of the Pseudoalteromonas Alterochromide Gene Cluster in Escherichia coli Represents a Promising Natural Product Exploratory Platform (2014)

Marine pseudoalteromonads represent a very promising source of biologically important natural product molecules. To access and exploit the full chemical capacity of these cosmopolitan Gram-(-) bacteria, we sought to apply universal synthetic biology tools to capture, refactor, and express biosynthetic gene clusters for the production of complex organic compounds in reliable host organisms. Here, we report a platform for the capture of proteobacterial gene clusters using a transformation-associated recombination (TAR) strategy coupled with direct pathway manipulation and expression in Escherichia coli. The ~34 kb pathway for production of alterochromide lipopeptides by Pseudoalteromonas piscicida JCM 20779 was captured and heterologously expressed in E. coli utilizing native and E. coli-based T7 promoter sequences. Our approach enabled both facile production of the alterochromides and in vivo interrogation of gene function associated with alterochromide's unusual brominated lipid side chain. This platform represents a simple but effective strategy for the discovery and biosynthetic characterization of natural products from marine proteobacteria.
Multi-user dynamic proofs of data possession using trusted hardware (2013)

In storage outsourcing services, clients store their data on a potentially untrusted server, which has more computational power and storage capacity than the individual clients. In this model, security properties such as integrity, authenticity, and freshness of stored data ought to be provided, while minimizing computational costs at the client, and communication costs between the client and the server. Using trusted computing technology on the server's side, we propose practical constructions in the provable data possession model that provide integrity and freshness in a dynamic, multi-user setting, where groups of users can update their shared files on the remote, untrusted server. Unlike previous solutions based on a single-user, single-device model, we consider a multi-user, multi-device model. Using trusted hardware on the server helps us to eliminate some of the previously known challenges with this model, such as forking and rollback attacks by the server. We logically separate bulk storage and data authentication issues to different untrusted remote services, which can be implemented either on the same or different physical servers. With only minor modifications to existing services, the bulk storage component can be provided by large-scale storage providers such as Google, CloudDrive, DropBox, and a smaller specialized server equipped with a trusted hardware chip can be used for providing data authentication. Our constructions eliminate client-side storage costs (clients do not need to maintain persistent state), and are suitable for situations in which multiple clients work collaboratively on remotely stored, outsourced data.
Cannabinoides: ¿posibles agentes antitumorales? (1999)

Loa cannabinoides, componentes activos del Cannabis sativa L., actuan en el organismo imitando a unos compuestos endogenos los endocannabinoides – mediante la activacion de receptores especificos situados en la superficie de las celulas. Ejercen efectos sintomaticos en pacientes con cancer. Por ejemplo, mejoran las nauseas y los vomitos provocados por la quimioterapia, estimulan el apetito y disminuyen el dolor. Ademas, los cannabinoides inhiben el crecimiento de los tumores en experimentos realizados en animales de laboratorio. Lo hacen modulando rutas claves de senalizacion celular, lo que da lugar a acciones antitumorales tales como la muerte por apoptosis de las celulas neoplasicas y la inhibicion de la angiogenesis del tumor. Es de destacar que parece ser que los cannabinoides son agentes antineoplasicos selectivos, ya que pueden matar a las celulas del tumor sin afectar perceptiblemente a la viabilidad de las celulas normales. Basandonos en estos resultados preclinicos, hemos llevado a cabo un estudio clinico piloto con ∆-tetrahidrocannabinol (THC) en pacientes con glioblastoma multiforme recidivante. El perfil de seguridad del THC, junto con su posible accion inhibidora del crecimiento de las celulas neoplasicas, pueden fijar las bases para futuros ensayos dirigidos a evaluar la posible actividad antitumoral de los cannabinoides. Palabras claves: cannabinoide, receptor, tumor, cancer, apoptosis, angiogenesis, terapia experimental, ensayo clinico.
Ruled Surfaces of Finite Type Gauss Map in $S^3$ (1999)

In this paper we showed that ruled surfaces of finte type Gauss map in are totally geodesic or products of two plane circles.
Immunotherapy and Checkpoint Inhibitors in Recurrent and Metastatic Head and Neck Cancer (2016)

Immune surveillance is well recognized as an important mechanism to prevent development or progression of head and neck cancers. Head and neck cancer cells can escape the immune system through multiple mechanisms including development of tolerance in T cells and inhibition of T-cell–related pathways, generally referred to as checkpoint inhibitors. This article highlights advances in immuno-oncology treatment approaches in recurrent and metastatic head and neck squamous cell carcinoma. Clinical trials are discussed in detail, with an emphasis on response dynamics, oncologic efficacy, safety, and tolerability of checkpoint inhibitors. In addition, developing concepts and ongoing studies in this setting are also reviewed.
Isolation from Lysogens v1 (2015)

This is a protocol from: Stedman,K. M., K. Porter, and M. L. Dyall-Smith. 2010. Chapter 6:The isolation of viruses infecting Archaea.Manual of Aquatic Viral Ecology. Waco, TX:American Society of Limnology and Oceanography. doi:10.4319/mave.2010.978-0-9845591-0-7 Please see the published manuscript for additional information.
In Vivo Imaging of Mammalian Cochlear Blood Flow Using Fluorescence Microendoscopy (2006)

Fluorescence microendoscopy permits visualization of cochlear microcirculation with micron-scale optical resolution and determination of blood flow velocities through analysis of video sequences.
Laboratory Quantification of Bone Marrow Concentrate Components in Unilateral Versus Bilateral Posterior Superior Iliac Spine Aspiration (2020)

Mesenchymal Stem Cells (MSCs) from Bone Marrow Concentrate (BMC) have emerged as a promising treatment for degenerative musculoskeletal pathologies, such as Osteoarthritis (OA). Many aspiration techniques have been described in the literature with little consensus on optimal methodology. This study aimed to compare MSC quantity in unilateral versus bilateral Posterior Superior Iliac Spine (PSIS) bone marrow aspirate concentrations. Patients with unilateral knee OA seeking treatment with intraarticular BMC were recruited and randomized to a unilateral PSIS Bone Marrow Aspiration (BMA) or a bilateral PSIS BMA of equal total volumes. BMA and BMC samples underwent laboratory analysis of Colony Forming Unit-Fibroblasts (CFU-fs) as a marker for MSCs, for quantification of Total Nucleated Cell (TNC) count, and CD-34 positivity, in addition to other metrics. Data from 26 patients were analyzed.Mean total CFU-fs were 1.9 times higher in the bilateral group (n=13) versus the unilateral group (n=13); 42,912 versus 23,038, respectively (p=0.17). The median number of CFU-fs cultured from 1 ml of BMC in the bilateral cohort was 33% higher than the unilateral group (2477 versus 1860 CFU-fs/ml, respectively (p=0.23). Despite the difference in CFU-fs, the TNC counts were similar between the two groups. This descriptive study suggests a lower volume; multisite draw-technique for BMA increases the absolute number of CFU-fs, and therefore the correlated MSC count. Due to the limited statistical power, these data will need to be further evaluated with a larger patient dataset and correlated with patient outcomes data to determine clinical significance. Keywords: Bone marrow aspiration technique; Bone marrow concentrate; Quantitative analysis; Mesenchymal stem cell.
Mass Spectrometric Characterization of Full-length Rat Selenoprotein P and Three Isoforms Shortened at the C Terminus (2002)

Selenoprotein P is an abundant extracellular glycoprotein. Its mRNA contains 10 UGAs in an open reading frame terminated by a UAA. This predicts that full-length selenoprotein P will contain 10 selenocysteine residues. Full-length selenoprotein P and three smaller isoforms that have identical N termini have been demonstrated. Selenoprotein P was purified from rat plasma, and the four isoforms were separated by heparin chromatography and SDS-PAGE. Mass spectrometric peptide analysis of the full-length isoform verified 357 of its 366 predicted amino acid residues, including its C terminus and all 10 selenocysteines. The C termini of the smaller isoforms were characterized by mass spectrometry. The shortened isoforms terminated where the second, third, and seventh selenocysteine residues were predicted to be. This suggests that all isoforms arise from the same mRNA and that the UGAs that specify the second, third, and seventh selenocysteines in full-length selenoprotein P can alternatively serve to terminate translation, producing the shorter isoforms.