gebhart/patrepeval huggingface dataset:
Molecular aggregation of solid aromatic polymers. II. Mechanical properties of aromatic polyimide film (1982)

Abstract Molecular aggregation of the aromatic polyimide poly(4,4′‐oxydiphenylene‐pyromellitimide) is influenced by the initial imidization temperature and by cold drawing. The effect of molecular aggregation in polyimides on their mechanical properties has been investigated. The density of a polyimide in which molecular aggregation gives an amorphous state is increased slightly by cold drawing. On the other hand, if molecular aggregation leads to a heterogeneous two‐phase structure, the density is decreased by cold drawing. With increasing initial imidization temperature, the α absorption peak in dynamic tensile measurements becomes broader and smaller, and shifts to a higher temperature. From analysis of correlations between molecular aggregation and mechanical properties, it is concluded that the mode of molecular motion corresponding to the α dispersion in polyimide is a long‐range cooperative motion of the main chain which is associated with the glass transition.
Production of Transgenic Mice (2003)

The term "transgenic " has been used since the beginning of the 1980s to define animals that had incorporated foreign DNA into their genome ( ,).Currently, transgenic animals include various species such as fish,poultry,rats,rabbits,pigs, sheep,goats,cattle,and mice ( ,).Mice remain the preferred system for exploring new trends in transgenic research mainly because they are easy to maintain,have short generations (, , wk on average),and produce large numbers of progeny (eight on average).Although gene transfer into mice can be achieved by several methods,such as retroviral infection,embryonic stem (ES)cell transfer or cell/embryo aggregation, the direct microinjection of purified DNA into the male pronucleus of fertilized mouse oocytes has been the most widely used technique for generating transgenic mice,with a rate of 5–30%of the pups born harboring the transgene ().Several books and review articles have discussed many aspects of this technology,and they provide good references for further readings ( –11).
TRIDNT: The Trust-Based Routing Protocol with Controlled Degree of Node Selfishness for MANET (2011)

In Mobile ad-hoc network, nodes must cooperate to achieve the routing purposes. Node misbehaviour due to selfish or malicious intention could significantly degrade the performance of MANET because most existing routing protocols in MANET are aiming at finding most efficiency path.
Optimizing Publish/Subscribe Systems with Congestion Handling (2008)

Despite its success, the Internet suffers from major shortcomings. Nowadays there is lot of attention toward changing the Internet architecture, in different layers to cope to challenges of high traffic demands and new types of applications. One of the architectural alternatives is changing client-server communication paradigm of original Internet to a Publish/subscribe communication paradigm. Since studying this new paradigm as well as any other architectural changes toward future Internet, should be done on top of TCP/IP stack, studying and experimenting of this new paradigm has been done over overlay networks. Overlay networks are new approach of academia to study and implement all kind of new services that are not possible or are difficult to be implemented on Internet network layer. The new paradigm itself faces some difficulties. The goal of this thesis was to look at congestion problem of publish/subscribe paradigm; Design and test a system to address congestion handling requirements of publish/subscribe systems and some of their Quality of service requirements with respect to congestion situation. The results of the design are evaluated against the given requirements. Different design alternatives are introduced and analyzed in order to rationalize the design. A reference implementation is developed as a proof of concept. The outcome of the design meets the requirements. The new model increases the control over the congestion and some quality of service requirements on a given pub/sub system. The work brought up some future work items on testing new models for better congestion management and also testing other Quality of service requirements.
Three-dimensional US of the fetus. Work in progress. (1994)

The technique has the potential for recording complete anatomic studies for review and visualization of detail that is difficult to perceive on conventional US scans.
Synthesis of the mixed lithium–magnesium, mixed amide (R,R/S,S)-[{LiMg(TMP)[CH2Si(Me)2N(SiMe3)]}2]: a conformationally-locked structure of five fused rings inducing two stereogenic nitrogen centres (2000)

Reaction of the magnesium amide Mg(TMP)2 with the lithium amide LiHMDS is accompanied by an unexpected, sterically-promoted hydrogen transfer/amine elimination process, to yield the novel title compound which is the first such heterometallic composition to contain a heteroleptic amide ligand set.
Transcriptional mapping of rabies virus in vivo. [UV radiation] (1978)

Synthesis of the proteins of rabies virus was studied in hamster cell infected with uv-irradiated virus. The uv target size of genes L, N, M/sub 1/, and M/sub 2/ was measured during primary transcription. Except for N, the target size of the remaining genes was considerably larger than that of their physical sizes. The data fit the hypothesis that four genes occupy a single transcriptional unit and that transcription of rabies virus proceeds in the order N, M/sub 1/, M/sub 2/, and L.
Study of wideband propagation in millimetric band (2006)

A complete wideband radio channel sounding campaign performed at 38.95 GHz is presented in this paper. A sounder based on correlation of pseudorandom maximal length sequences has been used, but introducing some novelties in the classical scheme of this kind of sounders. Different antenna pattern and polarization have been combined with three groups of environments, indoor, outdoor and indoor-outdoor, to increase the variability of the channel characterization obtained. Wideband estimated parameters achieved show qualitatively good expectative for the use of high data rate applications in this frequency band even in indoor conditions.
Cell lineage study in the liver using retroviral mediated gene transfer. Evidence against the streaming of hepatocytes in normal liver. (1994)

The fate of normal hepatocytes in adult rat liver was studied after genetic labeling using the Escherichia coli beta-galactosidase gene coupled to a nuclear localization signal. The marker gene was introduced by direct in vivo retroviral-mediated gene transfer into hepatocytes 24 hours after partial hepatectomy. Analysis of beta-galactosidase expression in the liver at various time after gene transfer revealed that labeled hepatocytes were distributed throughout the entire lobule with a predominance in the periportal and mediolobular regions. Long-term experiments demonstrated that division of hepatocytes did occur as was revealed by the increasing number of beta-galactosidase-positive cells in isolated clusters. There was no evidence for the participation of stem cells in this process. Moreover, we found that after more than 1 year, the pattern of distribution of positive cells within the lobule was not modified. This suggests that hepatocytes do not migrate from the portal space to the perivenous region, as has been previously hypothesized.
Facial Expression Recognition Using ALGBP-TOP (2013)

Human-computer interaction (HCI) is the most application of automatic facial expression recognition. In this paper, a dynamic texture-based approach is considered to recognize the facial expressions. The local binary patterns in three orthogonal planes (LBP-TOP) are represented to combine motion and appearance of texture. Our proposed algorithm based on the average Gabor filters and LBP-TOP (that is called ALGBP-TOP) features is recognized facial expressions. We evaluate our proposed algorithm on the Cohn-Kanade facial expression database that obtains an acceptable recognition accuracy of 94.42% by using the ALGBP-TOP features.
Supplementary Figure 5 from Suppression of Nonhomologous End Joining Repair by Overexpression of HMGA2 (2023)

Supplementary Figure 5 from Suppression of Nonhomologous End Joining Repair by Overexpression of HMGA2
Tailoring the highest occupied molecular orbital level of poly(N-vinylcarbazole) hole transport layers in organic multilayer heterojunctions (2016)

We report the tailoring of the electronic structure of poly(N-vinylcarbazole) (PVK) using a mixture layer of polyaniline:poly(p-styrenesulfonic acid) (PANI:PSS) in organic multilayer PVK/PANI:PSS/poly(3,4-ethylenedioxythiophene):PSS heterojunctions. The overall electronic structure of the PVK overlayer was systematically down-shifted while the work function of PANI:PSS increased as a function of the PSS-to-PANI weight ratio for the ratio range from 1 to 11 in the PANI:PSS film. The down-shift in the highest occupied molecular orbital of PVK markedly reduced the hole injection barrier from PVK to quantum-dot (QD) layers in QD-light emitting diode (QD-LED) structures, resulting in superior electrical and electroluminescent characteristics for QD-LEDs. The influences of PANI:PSS thickness on the electronic structure of PVK and the performance of QD-LEDs are also discussed.
Synthesis and Pharmacological Activity of 4-Amino-5-chloro-2-methoxy-N-[(2S,4S)-1-ethyl-2-hydroxymethyl-4-pyrrolidinyl]benzamide (TKS159) and Its Optical Isomers. (1999)

Of 4-amino-5-chloro-2-methoxy-N-(1-ethyl-2-hydroxymethyl-4- pyrrolidinyl)benzamide, four optical isomers, (2S,4S)-1 (TKS159), (2S,4R)-25, (2R,4S)-26 and (2R,4R)-27, were prepared from optically active 4-amino-1-ethyl-2-hydroxymethylpyrrolidine di-p-toluenesulfonate [(2S,4S)-14, (2S,4R)-17, (2R,4S)-20 and (2R,4R)-23, respectively]. The requisites, (2S,4S)-14, (2S,4R)-17, (2R,4S)-20 and (2R,4R)-23, were prepared from a commercially available trans-4-hydroxy-L-proline. The absolute configurations of (2S,4S)-1 (TKS159), (2S,4R)-25, (2R,4S)-26 and (2R,4R)-27 were spectroscopically determined. Of the benzamide derivatives, four optical isomers, (2S,4S)-1, (2S,4R)-25, (2R,4S)-26 and (2R,4R)-27, showed a relatively potent affinity for 5-hydroxytryptamine 4 (5-HT4) receptors in a radioligand binding assay ([3H]GR113808). The activities of 25-27 were less effective than that of 1 for the gastric emptying of a phenol red semisolid meal in rats. All this suggests that the most potent of the isomers was 4-amino-5-chloro-2-methoxy-N-[(2S,4S)-1-ethyl-2- hydroxymethyl-4-pyrrolidinyl]benzamide (1).
Detection of stochastic waves in plasma monolayer crystals from video images (2000)

The motion of dust particles confined in plasma monolayer crystals is analyzed from video images, under conditions dominated by dust-neutral collisions. In these crystals, dust-neutral collisions will act as a random driving force, exciting phonons with a stochastic nature. The phonons are investigated using standard statistical tools, including both single- and multiparticle correlation functions. Single-particle correlations as obtained from the velocity autocorrelation function yield oscillations in a very narrow frequency band. Similar behaviors have previously been reported for strongly coupled one-component plasmas, and for trapped Brownian particles. Spatial correlations in the crystal lattice are studied from multiparticle correlation functions, suggesting an average wavelength slightly larger than the dimension of the crystal. Throughout the crystal, the dust velocity amplitude and polarization vary significantly, with the main variation in the radial direction out of the crystal center. This suggests the observed wave feature is a standing wave with a stochastic amplitude, dominated by its lowest eigenfrequency.
Sudoxicam and related N-heterocyclic carboxamides of 4-hydroxy-2H-1,2-benzothiazine 1,1-dioxide. Potent nonsteroidal antiinflammatory agents (1972)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSudoxicam and related N-heterocyclic carboxamides of 4-hydroxy-2H-1,2-benzothiazine 1,1-dioxide. Potent nonsteroidal antiinflammatory agentsJoseph G. Lombardino and Edward H. WisemanCite this: J. Med. Chem. 1972, 15, 8, 848–849Publication Date (Print):August 1, 1972Publication History Published online1 May 2002Published inissue 1 August 1972https://pubs.acs.org/doi/10.1021/jm00278a016https://doi.org/10.1021/jm00278a016research-articleACS PublicationsRequest reuse permissionsArticle Views276Altmetric-Citations79LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Formation and Reactivity of Novel Pyranosidic Nicholas Oxocarbenium Ions: Access to C‐Ketosides and Branched‐Chain C‐Ketosides. (2006)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Acute Drug and Toxin Induced Pancreatitis (1985)

Hepatotoxic agents can be classified into those that are intrinsic toxins and those that provoke idiosyncratic reactions in the host. Idiosyncratic reactions may be the direct result of hypersensitivity or be secondary to a toxic metabolite of the drug. There is no evidence that acute drug-induced pancreatitis can lead to chronic pancreatitis. Management strategies are discussed.
Harnessing Intelligent Agent Technology to "Superteach" Reasoning (2006)

After briefly explaining our ultimate educational goal with respect to reasoning (to “superteach ” reasoning), and our theoretical foundation, we give an overview of some of our attempts to build and harness intelligent agents in order to reach this goal. We end with coverage of the Slate system, which inherits its power from lessons learned in connection with the engineering of its more primitive predecessors.
[Stress-induced alteration of the anticonflict effect of anxiolytics]. (2003)

The influence of stress of various etiology (prolonged isolation, anavoidable electrostimulation, paradoxical sleep deprivation, transport stress) on the activity of anxiolytics (tranquilizers) in the conflict situation was studied in inbreed white male rats. It was established that the anticonflict effect of highly effective anxiolytics decreases under the action of stress, the activity of gidazepam remains unchanged, while the drugs of moderate efficacy loose their activity. The degree of changes and the rate of restoration of the initial activity depends on the efficacy of anxiolytics, the strength and duration of stress, and on the duration of drug administration after stress. The possible mechanism of this phenomenon can be the stress-induced activation of the endogenous system of anxiogenic ligands.
New Cassane-Type Diterpenes of Caesalpinia crista from Myanmar (2005)

Seven new cassane-type diterpenes, caesalpinin MF-ML (1-7), and a new norcassane-type diterpene, norcaesalpinin MD (8), have been isolated from the CH2Cl2 extract of seed kernels of Caesalpinia crista from Myanmar, together with sixteen known cassane-type diterpenes, 7-acetoxybonducellpin C, caesaldekarin e, caesalmin C, caesalmin G, 2-acetoxycaesaldekarin e, zeta-caesalpin, caesalpinin D, caesalpinin E, caesalpinin F, caesalpinin H, caesalpinin I, caesalpinin J, caesalpinin K, caesalpinin M, caesalpinin N, and caesalpinin O. The structures of the isolated compounds were elucidated by the use of spectroscopic techniques.
Protein penetration as a tool for the investigation of langmuir films derived from erythrocytes (1980)

Study of lipid bilayers by such techniques as the formation of black lipid membranes shows that these structures have a low mechanical strength and stability as compared with naturally occurring biomembranes. Nevertheless it is generally believed that the major structural components of membranes are the phospholipids and that the proteins which reside in them largely consist of enzymes. This experiment was designed to test the hypothesis that there exists a non-lipid component in some membranes which makes a considerable cont~bution to their mechanical coherence and stability. It was decided to study erythrocyte membranes as there exist well-known techniques for their isolation and for the removal of extrinsic proteins, such as spectrin, which are attached to them. We used such purified membranes as a starting point for the preparation of Langmuir films. We then injected watersoluble proteins beneath these layers and studied the effects of protein penetration on their isotherms. The behaviour of these monolayers was quite different from that of monolayers prepared from various mixtures of lipids alone. Experiments described below show that the additions component which brings about this difference is a protein.
Influence of Different Conditioning Methods on Force and Fatigue Resistance in Chronically Stimulated Skeletal Muscles (1996)

A study was undertaken to compare different conditioning methods for the transformation of latissimus dorsi muscle into a fatigue resistant one for application in circulatory assist. In ten sheep four electrodes were sutured to the epineurium of the left thoracodorsal nerve for indirect electrical stimulation of the latissimus dorsi muscle. In six sheep a "carousel stimulation," a special multichannel stimulation, in combination with a recently developed conditioning protocol was used for muscle conditioning (multichannel method). In four sheep, a conventional stimulation protocol using single channel stimulation was applied for transformation of the muscle (single channel method). The final experiments were carried out when fatigue resistance was obtained. The maximum tetanic forces at different preloads were determined and fatigue resistance was tested during 20 minutes of continuous stimulation. Both conditioning patterns led to fatigue-free chronic stimulation. Muscles conditioned by multichannel stimulation exhibited between 20% and 33% less force than the contralateral unconditioned muscles, whereas in the single channel group this loss was between 32% and 43%. Thus, the multichannel method revealed relatively superior in preserving muscle force for chronic stimulation.
NVG training developments in The Netherlands (2007)

The rapid recovery from the postural and ocular motor asymmetries produced by unilateral vestibular damage (vestibular compensation) has been presented as an example of plasticity in the central nervous system. A recent model (J. Neurophysiol., 51 (1984) 242-259) has identified the fibers joining the two vestibular nuclei in the brainstem (the vestibular commissures) as the site of the plastic changes. We report that in guinea pigs, compensation of postural symptoms still occurs after sectioning these commissural fibers. We suggest that a number of mechanisms may be responsible for vestibular compensation, including some which are independent of the vestibular commissures.
Water-Soluble Organometallic Compounds. 6.1Synthesis, Spectral Properties, and Crystal Structures of Complexes of 1,3,5-Triaza-7-phosphaadamantane with Group 10 Metals (1997)

The syntheses of a variety of group 10 metal complexes of the water-soluble phosphine triazaphosphaadamantane (PTA) are described. Treatment of Ni(NO3)2 with NaNO2 and PTA provides the nitrosyl complex [Ni(NO)(PTA)3]NO3 (1). Complex 1 is soluble in water, DMSO, and CH3CN but insoluble in THF, acetone, or hydrocarbons. X-ray crystallography shows the nitrosyl ligand to be coordinated in a near linear mode (∠Ni−N−O = 171.5(4)°) with a Ni−N bond length of 1.653(4) Å. Concordantly, the υ(NO) vibration in H2O occurs at 1830 cm-1. The series of zerovalent M(PTA)4 (M = Ni, Pd, Pt) complexes, 2, 3, and 6 have been prepared in good yields by several procedures: (i) the ligand exchange reaction of Ni(cod)2 with PTA; (ii) the reduction of PdCl2 or PtCl2 with hydrazine in the presence of PTA; and (iii) the ligand exchange reaction of Pt(PPh3)4 with PTA. All three derivatives are very water soluble (0.30 M) and resistant to PTA dissociation in solution at ambient temperature. Complexes 2, 3, and 6 can be crystallized from 0.10 M HCl to afford the nitrogen-protonated derivatives, [M(PTAH)4]Cl4. These salts were characterized by X-ray crystallography and shown to exist as slightly distorted tetrahedra with one nitrogen atom of each PTA ligand protonated. The M−P bond lengths are shorter than those found in related derivatives containing poorer electron-donating and/or sterically more encumbering phosphine ligands. The cis-MCl2(PTA)2 (M = Pd and Pt) derivatives, 4 and 7, were obtained by the metathesis reaction of (NH4)2PdCl4 or K2PtCl4 with PTA in refluxing ethanol. When the palladium reaction was carried out in a large excess of PTA, formation of the zerovalent Pd(PTA)4 complex occurred via the intermediacy of the [Pd(PTA)3Cl]+ cation as indicated by 31P NMR and mass spectrometry. The X-ray structures of the Pd(II) and Pt(II) derivatives, cis-PdCl2(PTA)2 and [cis-PtCl2(PTAH)2]Cl2, revealed these to exist as slightly distorted square planar complexes where the P−M−P angles are expanded to 94.4°. The platinum derivative, which contains the nitrogen protonated PTA ligands, displays an extensive array of hydrogen bonding and electrostatic interactions involving water, PTA, and HCl.
Assembly of Outer Membrane β-Barrel Proteins: the Bam Complex (2011)

The major class of integral proteins found in the outer membrane (OM) of E. coli and Salmonella adopt a β-barrel conformation (OMPs). OMPs are synthesized in the cytoplasm with a typical signal sequence at the amino terminus, which directs them to the secretion machinery (SecYEG) located in the inner membrane for translocation to the periplasm. Chaperones such as SurA, or DegP and Skp, escort these proteins across the aqueous periplasm protecting them from aggregation. The chaperones then deliver OMPs to a highly conserved outer membrane assembly site termed the Bam complex. In E. coli, the Bam complex is composed of an essential OMP, BamA, and four associated OM lipoproteins, BamBCDE, one of which, BamD, is also essential. Here we provide an overview of what we know about the process of OMP assembly and outline the various hypotheses that have been proposed to explain how proteins might be integrated into the asymmetric OM lipid bilayer in an environment that lacks obvious energy sources. In addition, we describe the envelope stress responses that ensure the fidelity of OM biogenesis and how factors, such as phage and certain toxins, have coopted this essential machine to gain entry into the cell.