gebhart/patrepeval huggingface dataset:
Application of a Digital Twin Virtual Engineering Tool for Ground Vehicle Maintenance Forecasting (2022)

&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;The integration of sensors, actuators, and real-time control in transportation systems enables intelligent system operation to minimize energy consumption and maximize occupant safety and vehicle reliability. The operating cycle of military ground vehicles can be on- and off-road in harsh weather and adversarial environments, which demands continuous subsystem functionality to fulfill missions. Onboard diagnostic systems can alert the operator of a degraded operation once established fault thresholds are exceeded. An opportunity exists to estimate vehicle maintenance needs using model-based predicted trends and eventually compiled information from fleet operating databases. A digital twin, created to virtually describe the dynamic behavior of a physical system using computer-mathematical models, can estimate the system behavior based on current and future operating scenarios while accounting for past effects. In this manner, the collection of real-time data of the physical vehicle can be compared with the virtual counterpart to assess the likelihood of degraded operation and recommend maintenance. This paper creates a digital twin for an off-road tracked ground vehicle with an accompanying parameter database. A modular architecture enables different design reconfigurations to evaluate various chassis subsystems and vehicle-ground mobility interfaces. A preventive maintenance algorithm is applied to monitor the operating behavior of the vehicle. The prediction tool, operating in parallel with the digital twin, may use model-based and sensory signal condition indicators to monitor vehicle performance. A case study investigates two operating scenarios: a virtual wheeled suspension system is degraded; and a virtual tracked vehicle experiences missing trackpads, which subtly alter the performances. The numerical results will offer insight into the pathway to begin creating a digital twin-based maintenance forecasting strategy.&lt;/div&gt;&lt;/div&gt;
Performance Analysis of SIMO Space–Time Scheduling With Convex Utility Function: Zero-Forcing Linear Processing (2004)

In a multiple-antenna system, an optimized design across the link and scheduling layers is crucial toward fully exploiting the temporal and spatial dimensions of the communication channel. In this paper, based on discrete optimization techniques, we derive a novel analytical framework for designing optimal space-time scheduling algorithms with respect to general convex utility functions. We focus on the reverse link (i.e., client to base station) and assume that the mobile terminal has a single transmit antenna while the base station has n/sub R/ receive antennas. In order that our proposed framework is practicable and can be implemented with a reasonable cost in a real environment, we further assume that the physical layer involves only linear-processing complexity in separating signals from different users. As an illustration of the efficacy of our proposed analytical design framework, we apply the framework to two commonly used system utility functions, namely maximal throughput and proportional fair. We then devise an optimal scheduling algorithm based on our design framework. However, in view of the formidable time complexity of the optimal algorithm, we propose two fast practical scheduling techniques, namely the greedy algorithm and the genetic algorithm (GA). The greedy algorithm, which is similar to the one widely used in 3G1X and Qualcomm high-data-rate (HDR) systems (optimal when n/sub R/=1), exhibits significantly inferior performance when n/sub R/>1 as compared with the optimal approach. On the other hand, the GA is quite promising in terms of performance complexity tradeoff, especially for a system with a large number of users with even a moderately large n/sub R/. As a case in point, for a system with 20 users and n/sub R/=4, the GA is more than 36 times faster than the optimal while the performance degradation is less than 10%, making it an attractive choice in the practical implementation for real-time link scheduling.
Influence of NaCl concentration on the optical scattering properties of water-based aerosols (2023)

We present the characterization of several atmospheric aerosol analogs in a tabletop chamber and an analysis of how the concentration of NaCl present in these aerosols influences their bulk optical properties. Atmospheric aerosols (e.g., fog and haze) degrade optical signal via light-aerosol interactions causing scattering and absorption, which can be described by Mie theory. This attenuation is a function of the size distribution and number concentration of droplets in the light path. These properties are influenced by ambient conditions and the droplet's composition, as described by Köhler theory. It is therefore possible to tune the wavelength-dependent bulk optical properties of an aerosol by controlling droplet composition. We present experimentation wherein we generated multiple microphysically and optically distinct atmospheric aerosol analogs using salt water solutions with varying concentrations of NaCl. The results demonstrate that changing the NaCl concentration has a clear and predictable impact on the microphysical and optical properties of the aerosol.
Serotype identification of Actinobacillus pleuropneumoniae by arbitrarily primed polymerase chain reaction (1993)

Rapid and accurate determination of the Actinobacillus pleuropneumoniae serotype involved in a disease outbreak is important both in limiting the severity of an outbreak and for tracing the source of the infecting organism. This study describes the use of arbitrarily primed polymerase chain reaction (AP-PCR) as a rapid, precise, and genetically based procedure to identify A. pleuropneumoniae. AP-PCR amplification of bacterial genomic DNA results in specific DNA profiles, which can be used to differentiate currently recognized serotypes. This technique is especially useful for identifying previously nontypeable and serologically cross-reactive A. pleuropneumoniae field isolates. Consecutive passages of isolates on different media, freezing, and subsequent infection of pigs did not alter the AP-PCR genomic profile. We propose the use of M13 and T3-T7 oligodeoxynucleotide primers for diagnostic and epidemiological identification of A. pleuropneumoniae by AP-PCR techniques.
Fetal gene therapy (2001)

Fetal gene therapy has the potential to treat inherited genetic diseases in utero before significant organ damage has occurred. Rapidly expanding stem cell populations may be targeted and the introduction of transgenes to the fetus during development of the immune system could result in immune tolerance and facilitate repeat treatment postnatally. Genetic diseases such as cystic fibrosis, which are life-threatening and for which there are no currently acceptable treatments available, are suggested targets for this therapy.Ultrasound may be a safe method of delivering a therapeutic gene into the fetus, although most studies have used more invasive techniques, even in large animal models. Viral vectors currently offer the most potential. Adenovirus-based vectors are stable, independent of host cell replication, efficient at tissue infection and have been used as a ‘pathfinder’ to test routes of administration. Unfortunately, they are also highly immunogenic and other systems based on retrovirus or adeno-associated virus may offer advantages because of their lower immunogenicity and potential for permanent transgene expression.Our group is developing the fetal sheep model for the investigation of ultrasound-guided gene therapy in utero. This model is suitable since the sheep fetus is tolerant to manipulations, has a consistent gestation period and shows many similarities with human pregnancy. We have demonstrated significant transfection of the fetal liver and adrenal cortex after ultrasound-guided percutaneous injection of the umbilical vein with adenoviral vectors in the late gestation sheep. We are investigating and here discuss alternative routes of administration to target the fetus in early gestation via ultrasound-guided minimally invasive techniques.
Abstract 1676: Associations between hormone therapy with incident colorectal cancer by p53 protein expression in a population-based cohort of older women (2012)

Abstract Background: Cigarette smoking (CS) is an established colorectal cancer (CRC) risk factor. The p53 protein, encoded by the TP53 tumor suppressor gene that is commonly mutated in CRC, is important in cell cycle arrest needed to repair DNA damage or induce apoptosis to prevent tumor propagation. In this prospective cohort study, we examined CS-associated CRC risks by p53 protein expression level in the population-based Iowa Women's Health Study (IWHS). Methods: The IWHS recruited 41,836 randomly selected Iowa women, ages 55-69 years, with a valid driver's license at study entry (1986). CS and other exposure variables were assessed at baseline, by self-report. Incident CRC cases were ascertained by annual linkage with the Iowa Cancer Registry. Archived, paraffin-embedded tissue specimens were collected from 732 CRC cases diagnosed through 12/31/2002. CS was categorized by smoking status (never, current, former), average number of cigarettes per day (1-19, 20-39, &amp;gt; 40) and cumulative pack-years (1-19, 20-39, &amp;gt; 40). P53 protein expression was determined by immunohistochemistry on tissue microarrays. Tumor cores were scored by combining both staining intensity and percent of cells stained to determine negative, low or high p53 protein expression levels. Multivariate Cox regression models were fit to estimate relative risks (RRs) and 95% confidence intervals (CIs). Results: Of the 732 available CRC cases, 486 (66%) had complete CS and p53 data. Associations between CS and CRC subtypes defined by p53 expression level are shown in the Table. Conclusions: These data demonstrate no clear heterogeneity of CS with CRC subtypes defined by p53 expression levels among older women. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 103rd Annual Meeting of the American Association for Cancer Research; 2012 Mar 31-Apr 4; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2012;72(8 Suppl):Abstract nr 1676. doi:1538-7445.AM2012-1676
L’entreprise libérée au service d’un projet collectif et du travail collaboratif dans un cabinet de conseil en RH et SIRH : le cas d’HR Conseil (2018)

HR Conseil effectue une relecture du modèle de l’entreprise libérée et l’adapte ainsi à la structure d’un cabinet de conseil. Avec à sa tête, deux leaders libérateurs, la structure est imprégnée de valeurs libérées et d’une vision chiffrée, propre aux co-fondateurs. Sa hiérarchie aplatie favorise la proximité entre les collaborateurs à toutes les strates du cabinet. Le management privilégie la confiance et la responsabilisation des consultants. Fidèle aux valeurs de l’entreprise libérée, la confiance et la liberté accordées aux consultants poussent la prise d’initiative et la créativité.<br>Cependant, le cabinet fait face à certaines limites au modèle, en termes de hiérarchie et d’adhésion aux valeurs de la part des consultants. Malgré une organisation horizontale, la hiérarchie reste marquée : les liens de subordination subsistent et la strate managériale est très exploitée. Étant responsabilisés très rapidement, les consultants ont une approche individualisée du travail et de l’évolution en interne. Leur sentiment d’appartenance est faible à la structure globale. Le cabinet favorise le développement d’une culture de l’informel qui rend la communication et les logiques d’évolution individualistes à défaut de soutenir le projet collectif.<br>Le modèle organisationnel du cabinet, dans son management, sa culture de la débrouille individuelle plutôt que du projet commun et ses difficultés à créer un sentiment d’appartenance pousse les consultants à s’organiser entre eux. Les collaborateurs privilégient les groupes de pairs pour travailler comme pour s’informer. Le sentiment d’appartenance se crée au niveau de l’équipe plus qu’au niveau du cabinet au global. Au-delà du sentiment d’appartenance, c’est même une véritable loyauté qui se développe entre les membres d’une même équipe.<br>HR Conseil favorise la création d’un collectif de travail opérationnel, en attestent la satisfaction du client, la hausse du chiffre d’affaires et l’engagement des consultants. En s’inspirant du modèle de l’entreprise libérée, le cabinet permet l’organisation d’un travail de groupe, régi par les règles de l’intelligence collective et la proactivité des consultants du cabinet. Le cabinet propose une structure ouverte, en cohérence avec le métier de consultant, et effectue une relecture du modèle organisationnel de l’entreprise libérée, plutôt qu’en y adhérant complètement.
Ampliative medicament allergy: concomitant sensitivity to multiple medicaments including yellow soft paraffin, white soft paraffin, gentian violet and Span 20 (1982)

A patient developed multiple rare medicament contact allergies including sensitivities to gentian violet, yellow and white soft paraffin, and Span 20 (sorbitan monolaurate). Nickel sensitivity antedated these medicament allergies. The possibility that nickel sensitivity is a marker of predilection to develop multiple medicament allergies was tested. We were unable to demonstrate an increased incidence of nickel sensitivity in a group of patients with 2 or more medicament allergies.
Human Papillomavirus Type 16 E7 Oncoprotein Can Induce Abnormal Centrosome Duplication through a Mechanism Independent of Inactivation of Retinoblastoma Protein Family Members (2003)

The human papillomavirus type 16 (HPV-16) E7 oncoprotein rapidly induces centrosome duplication errors in primary human cells, thereby increasing the propensity for multipolar mitoses, which can lead to chromosome missegregation and aneuploidy. We analyzed a series of HPV-16 E7 mutants and demonstrate that this biological activity of the E7 oncoprotein is mediated by sequences encompassing the core pRB binding site but is independent of its ability to inactivate the retinoblastoma tumor suppressor protein pRB and the related pocket proteins p107 and p130. In addition, interaction of E7 with the S4 subunit of the 26S proteasome and dysregulation of cdc25A transcription are also dispensable for the induction of centrosome duplication errors. Consistent with these results, expression of HPV-16 E7 induces abnormal centrosome duplication in a cell line that lacks functional pRB and in mouse embryo fibroblasts that are deficient for pRB, p107, and p130. These results demonstrate that the molecular mechanism whereby HPV-16 E7 induces centrosome duplication errors is independent of its ability to inactivate pRB, p107, and p130 or to interact with the S4 proteasome subunit.
Sensor and open-phase fault detection and isolation for three-phase AC drives (2010)

This paper deals with an on-line fault detection and isolation method for three-phase AC drives. The method is based on the detection of the stator current positive- and negative-sequence fundamental components expressed in the stationary αβ reference frame. These components allow calculating two fault indices used for the detection and isolation of an open-phase fault and a sensor fault, i.e. a disconnected sensor. The decision criterion is based on the CUSUM algorithm. The method includes a phase locked-loop performing the frequency adaptation needed to achieve fault detection on a wide speed range and even during speed transient. An experimental validation of the proposed method showing its effectiveness is carried out. (6 pages)
Recent Advances in Trustworthy Explainable Artificial Intelligence: Status, Challenges and Perspectives (2021)

This is a survey paper on Explainable Artificial Intelligence (XAI).
ChemInform Abstract: 1,2,3‐Thiadiazoles with Unsaturated Side Chains ‐ Monomeric Building Blocks for Photoresists. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Male and female Cydia pomonella (Lepidoptera: Olethreutidae) larvae produce and respond to aggregation pheromone (2004)

Insect aggregation pheromones are defined as chemical substances produced by members of one or both sexes that induce members of both sexes to form aggregations (Borden 1984). Aggregation pheromones are typically emitted by and attract adult insects. Interestingly, larvae of the codling moth, Cydia pomonella L. (Lepidoptera: Olethreutidae), seeking pupation sites will aggregate in response to pheromone produced by cocoon-spinning conspecific larvae (Duthie et al. 2003). Such aggregations may be part of a mating strategy in which protandrous males are arrested by sex pheromone emanating from mature female pupae, thus allowing mating to ensue as soon as a female moth ecloses (Duthie et al. 2003). The cocoon-derived pheromone also attracts the specialist prepupal parasitoid Mastrus ridibundus Gravenhorst (Hymenoptera: Ichneumonidae), which “eavesdrops” on pheromonal communication of cocoon-spinning larvae (Jumean et al. 2004).
Gene Therapy Protocols (2008)

In Gene Therapy Protocols, Volumes 1 &amp; 2, internationally recognized investigators describe cutting-edge laboratory techniques for the study of Production and In Vivo Applications of Gene Transfer Vectors (Volume 1) and Design and Characterization of Gene Transfer Vectors (Volume 2). The field of gene therapy has undergone remarkable advances, promising to impact human healthcare significantly in the twenty-first century. Today’s technologies can deliver genetic material safely and effectively to cells to slow or halt the progression of disease, and to help repair or regenerate damaged or lost tissues. In this first volume of Gene Therapy Protocols: Production and In Vivo Applications of Gene Transfer Vectors, readers will find a comprehensive resource of current and emerging methods for the production of viral and non-viral gene transfer vectors, as well as detailed protocols for critical applications in stem cell biology, cancer, diabetes, HIV and tissue engineering. This first volume of the new and completely revised third edition of Gene Therapy Protocols will prove a necessary tool for graduate students and postdoctoral fellows and invaluable to basic and clinical researchers in both industry and academia
2P2-I23 Study of Effect That Haptic Sensibility Give to the Attribution of Own Actions to Self or Others (2008)

Human cognitive mechanisms have been studied for designing user-friendly interface. One of the key issues is the attribution of own actions to the intention of self or others. It is known that patients with schizophrenia who sometimes attribute their own actions to the intentions of others may perceive themselves as causing events which they do not in fact control, when they feel they are in voluntary movement. In this study, we design the experiment using a haptic device in order to investigate the difference of attribution of own actions when subjects lose haptic stimuli which would happen under normal circumstances. In the result, we show that haptic stimuli does not have implications for the attribution of own actions when anticipated actions happen, but influence it when actions happen with time delay.
A Multi-Well Review of Coiled Tubing Force Matching (2003)

Abstract To increase the predictability of successful coiled tubing operations, a review of recorded versus predicted weights was undertaken for several Statoil operated Norwegian platforms. Results from thirty-three wells were analysed and showed that a coefficient of friction of 0.24 was applicable in most wells. Additionally, it was confirmed that deviation complexity, production rates and direction of travel had no effect on the friction coefficient.
Mild and Stereoconvergent Palladium-Catalyzed Carbonyl Alkenation Reaction of α,β-Unsaturated Aldehydes (1998)

The addition of preformed ketone and ester enolates to α,β-unsaturated aldehydes 1 followed by in situ protection leads to the carbonates 3, 7, 8, 11, and 13. They are converted into sensitive functionalized dienes 4, 9, 12, and 14 by a smooth palladium-catalyzed elimination. Both syn- and anti-carbonates 7 and 8 lead to E-dienes 9 in a stereoconvergent manner.
Penicillium coffeae,a new endophytic species isolated from a coffee plant and its phylogenetic relationship toP. fellutanum, P. thiersiiandP. brocaebased on parsimony analysis of multilocus DNA sequences (2005)

Penicillium coffeae is described as a novel endophyte isolated from a Coffea arabica L. plant in Hawaii. The species is slow growing with short, vesiculate, monoverticillate conidiophores. Phylogenetic analysis using three loci shows that P. coffeae forms a strongly supported clade with P. fellutanum, P. charlesii, P. chermesinum, P. indicum, P. phoeniceum and P. brocae. Phenotypic ally these species are quite similar but can be distinguished. The EF-1α gene from P. fellutanum, P. charlesii, P. chermesinum and P. indicum lack introns, P. coffeae and P. phoeniceum have a previously unknown intron at codon 20 and P. brocae and P. thiersii isolates have a single intron at codon 26. The most parsimonious interpretation of intron changes on the strongly supported phylogenetic tree requires the gain of a novel intron at position 20 and loss of intron 26 to arrive at the current distribution of introns in this gene. This is one of only a few examples of intron gain in genes.
Occult intraocular foreign body masquerading as panuveitis: inductively coupled mass spectrometry and electrophysiologic analysis (2011)

Retained intraocular foreign bodies (IOFB) may rarely present as chronic uveitis, either with isolated anterior uveitis or with posterior segment inflammation. The heavy metals copper and iron may lead to both acute and chronic inflammatory processes resulting in severe inflammation, retinal degeneration, and resultant visual loss. Penetrating or perforating ocular injuries are easily recognizable in the majority of cases; however, a high index of suspicion is necessary to recognize an occult penetrating injury because of the severe visual impairment that can ensue. We describe an unusual case of a retained IOFB, which presented 6 months after a probable occult penetrating injury from metallic IOFB trauma. The severity of the patient's inflammation on presentation and retinal findings in the contralateral eye prompted further diagnostic testing including inductively coupled mass spectrometry of the IOFB and electrophysiologic testing. This rare clinical scenario, laboratory findings, and therapeutic considerations are presented.
Case of chronic‐phase chronic myelogenous leukemia with an abdominal hematopoietic tumor of leukemic clone origin (2004)

We report a 59-year-old man with chronic myelogenous leukemia (CML) in chronic phase who presented with a large abdominal tumor. Biopsy revealed proliferation of granulocytic-, erythroid-, and megakaryocytic-lineage cells in a retroperitoneal lymph node. The BCR/ABL fusion gene was detected on a paraffin-embedded tissue section of the lymph node by double-color fluorescence in situ hybridization, indicating an extramedullary hematopoietic tumor of CML origin. This patient has achieved a complete cytogenetic response for 19 months with imatinib mesylate (STI571; Gleevec), in association with the regression of the tumor. However, the development of an extramedullary tumor in chronic-phase CML generally indicates a poor prognosis, because it commonly consists of blast proliferation and is followed by blast crisis in the marrow within a few months. This case, therefore, points to the importance of histological examination of extramedullary tumors in CML for evaluation of disease status and for therapeutic decisions.