gebhart/patrepeval huggingface dataset:
TIGR in Iraq and Afghanistan: Network-adaptive distribution of media rich tactical data (2009)

The Tactical Ground Reporting (TIGR) system provides a unique multimedia patrol preparation and debriefing tool tailored to the needs of the patrol leader, and is used by all U.S. Army brigades in Iraq and Afghanistan. The distribution of data from geographically dispersed patrols requires network awareness and policy flexibility. The TIGR system utilizes an application overlay on to the tactical network that is tailored to the distribution of rich media. This architecture results in the theater-wide replication of compressed reports and meta-data, while the storage of full-quality media is distributed to the node closest to where the media was created. Thumbnail and other compressed media representations are replicated according to policy to meet soldier needs. Full-quality media can be accessed on demand from any location in the network. Network utilization is controlled by a policy-based content subscription system, a priority queuing mechanism, and the discrete scheduling of network traffic. In this paper, we focus on the requirements for media rich tactical applications, detail a system that meets those requirements, and discuss experiences using TIGR in theater.
The value of monitoring amended reports in cytopathology quality programs: A biennial review (2022)

Studying amendment reports is an underrecognized and valuable quality assurance tool. Amendments can help provide information about types of errors, monitor laboratory processes, and help guide quality improvement endeavors.
SOC CMOS technology for personal internet products (2003)

Worldwide demand for Personal Internet Products is increasing rapidly, and will shape the directions of CMOS technology in the years ahead. Personal Internet Products are loosely defined in this paper as communication, computing and consumer products, which are enabled by the Internet: cell phones, PDAs, WLANs, Internet audio/video, ADSL, cable modems etc. Personal Internet Products are based on Digital Signal Processing (DSP) and analog functionality. They are made accessible to billions of people around the globe by intense focus on cost through SOC integration. In the Internet Age, Moore's Law will continue to be a technology imperative for the semiconductor industry. But SOC integration will be an additional technology imperative that drives down the cost of Personal Internet Product to mass market levels. SOC integration for Personal Internet Products requires the integration of analog, power analog, RF and memory onto the digital baseband processor, which is fabricated in high density, high performance, low cost digital CMOS technology. This paper describes the challenges and some of the solutions to achieve this vision.
miR‑4295 promotes cell proliferation, migration and invasion of osteosarcoma through targeting interferon regulatory factor 1 (2020)

Osteosarcoma (OS) is the most common form of primary malignant bone tumor. Despite encouraging progress in the treatment of OS, the survival rate for patients with OS has remained unchanged over the past 40 years. It has been established that miRNA plays a crucial regulatory role in the progression and development of OS. To explore the potential association of miRNAs with OS, bioinformatics techniques were used to screen for differentially expressed miRNA genes in OS in the Gene Expression Omnibus database. In the GSE70367 database, it was revealed that miR-4295 expression was abnormally elevated in the expression of OS cells. To characterize the potential function of miR-4295 in OS, the expression levels of miR-4295 in 30 samples of OS and adjacent normal tissues was examined. The results revealed that the expression of miR-4295 was significantly increased in OS tissues compared with the paired normal tissues. Moreover, the expression levels of miR-4295 in OS cell lines (MG-63 and Saos-2) were significantly higher compared with those in the normal human mesenchymal stem cells. In addition, miR-4295 was associated with OS cell proliferation, migration and invasion. Furthermore, it was demonstrated that the expression of interferon regulatory factor (IRF)1, a tumor suppressor, was regulated by miR-4295 directly in OS cells. Taken together, the present results revealed that miR-4295 may act as a tumor activator by targeting IRF1 during the progression of OS. Investigating miR-4295 may provide novel insight into the mechanisms of OS metastasis, and inhibition and targeting miR-4295 may be a novel therapeutic strategy for the treatment of OS.
Abstract 118: Assembly of the Nlrp3 Inflammasome Regulates NET Formation and is Promoted by the Vimentin Intermediate Filament Cytoskeletal System (2019)

Neutrophils and neutrophil extracellular traps (NETs) play a pivotal role in innate immunity and inflammation, thus significantly contributing to the development and progression of autoimmune diseases and thrombo-occlusive disorders. One of the major signaling eventsduring the innate immune response and inflammation is the secretion of the pro-inflammatory cytokines IL-1ß and IL-18 after inflammasome activation. The most prominent inflammasome in the innate immune system is composed of the NLR Family Pyrin Domain-Containing 3 (NLRP3) protein. Although the NLRP3 inflammasome is highly expressed in neutrophils, nothing is known about its possible role in NET formation (NETosis). Neutrophil stimulation with nigericin, a K + ionophore and a well-known activator of the NLRP3 inflammasome, results in assembly of the NLRP3 inflammasome, observed as ASC/speck formation, and subsequent NETosis. To investigate the contribution of the NLRP3 inflammasome in NETosis, MCC950 was used to inhibit NLRP3 signaling. This resulted insignificantly decreased NET formation in both murine and human neutrophils after activation with nigericin and monosodium urate crystals (MSU) or ionomycin, a common NETosis stimulant. Since NLRP3 activation in macrophages is significantly promoted by the vimentin intermediate filament network, we investigated NET formation in vimentin null mice. Neutrophils from vimentin null mice show a significant decrease in NETosis after stimulation with nigericin, MSU, or ionomycin, as well as a reduction in the assembly of ASC/speck compared to neutrophils from wild-type mice. Taken together, our results demonstrate that the NLRP3 inflammasome activation plays an important role in the process of NETosis and may, in part, explain why many diseases aggravated by NETs are also accompanied by increased activation of NLRP3 inflammasome.
A phase II, single-arm study of AS1411 in metastatic renal cell carcinoma (RCC). (2010)

4590 Background: AS1411 is a DNA aptamer that targets nucleolin. Although normally present in the nucleolus, nucleolin is overexpressed and shows localization to the plasma membrane in renal and other cancer cells. A dose-escalating phase I trial of AS1411 monotherapy reported 1 complete response (CR) and 1 partial response (PR) among 12 patients with advanced RCC. A randomized phase II trial in AML reported increased CR rates when AS1411 was added to high-dose cytarabine. Methods: This phase II single-arm study evaluated AS1411 monotherapy in patients with metastatic, predominantly clear cell, RCC who had failed, or shown intolerance to, ≥1 prior treatment, including a tyrosine kinase inhibitor. AS1411 was administered at 40 mg/kg/day CI days 1-4 of a 28 day cycle for 2 cycles. Response evaluation using RECIST occurred every 8 weeks from the start of therapy until disease progression (performed by investigators and by an independent radiologist). The primary endpoint was response rate (CR+PR); progression-free survival (PFS), duration of response, and safety were secondary endpoints. Pharmacokinetic (PK) analysis was performed. Results: 35 patients were enrolled and treated; the median no. prior therapies was 2 (range 1-7). 33 completed 2 cycles of treatment. Independent response assessment indicated 1 PR (3%) and 21 cases of stable disease (SD; 60%); investigator assessment indicated 1 PR (3%) and 12 SD (34%). The patient achieving a PR exhibited a decreased sum of unidimensional target lesion measurements of ≥ 80%, and remains in PR at 5.9 months. Independently assessed median PFS was 3.9 months. No ≥ grade 4 adverse events were recorded; fatigue and constipation were the most common grade 1-3 adverse events occurring in 29% and 34% of patients, respectively. No other toxicity was observed in more than 10% of patients. PK analysis demonstrated a median steady-state plasma concentration of 21 μ g/mL, which is similar to the IC50 concentration identified for renal cancer cell lines in vitro. Conclusions: AS1411 has activity in RCC with minimal toxicity; PFS was comparable to that seen with active agents in the refractory setting. Further studies are needed to determine the optimal dosing and scheduling for this novel therapeutic. Author Disclosure Employment or Leadership Position Consultant or Advisory Role Stock Ownership Honoraria Research Funding Expert Testimony Other Remuneration Antisoma Antisoma
Guidance on radiation dose limits for the lens of the eye: overview of the recommendations in NCRP Commentary No. 26 (2017)

Purpose: This review summarizes the conclusions and recommendations of the new National Council on Radiation Protection and Measurements (NCRP) Commentary No. 26 guidance on radiation dose limits for the lens of the eye. The NCRP addressed radiation protection principles in respect to the lens of the eye, discussed the current understanding of eye biology and lens effects, reviewed and evaluated epidemiology, and assessed exposed populations with the potential for significant radiation exposures to the lens while suggesting monitoring and protection practices.Conclusions: Radiation-induced damage to the lens of the eye can include the loss of clarity resulting in opacification or clouding several years after exposure. The impact is highly dependent on the type of radiation, how the exposure of the lens was delivered, the genetic susceptibilities of the individual exposed, and the location of the opacity relative to the visual axis of the individual. The preponderance of epidemiological evidence suggests that lens damage could occur at lower doses than previously considered and the NCRP has determined that it is prudent to reduce the recommended annual lens of the eye occupational dose limit from an equivalent dose of 150 mSv to an absorbed dose of 50 mGy. Significant additional research is still needed in the following areas: comprehensive evaluation of the overall effects of ionizing radiation on the eye, dosimetry methodology and dose-sparing optimization techniques, additional high quality epidemiology studies, and a basic understanding of the mechanisms of cataract development.
Technology reviews: Dynamic curtain wall systems (1992)

We present a representative review of existing, emerging, and future technology options in each of five hardware and systems areas in envelope and lighting technologies: lighting systems, glazing systems, shading systems, daylighting optical systems, and dynamic curtain wall systems. The term technology is used here to describe any design choice for energy efficiency, ranging from individual components to more complex systems to general design strategies. The purpose of this task is to characterize die state of the art in envelope and lighting technologies in order to identify those with promise for advanced integrated systems, with an emphasis on California commercial buildings. For each technology category, the following activities have been attempted to the extent possible: Identify key performance characteristics and criteria for each technology. Determine the performance range of available technologies. Identify the most promising technologies and promising trends in technology advances. Examine market forces and market trends. Develop a continuously growing in-house database to be used throughout the project. A variety of information sources have been used in these technology characterizations, including miscellaneous periodicals, manufacturer catalogs and cut sheets, other research documents, and data from previous computer simulations. We include these different sources in order to best show the type and variety of data available, however publication here does not imply our guarantee of these data. Within each category, several broad classes are identified, and within each class we examine the generic individual technologies that fall into that class.
Verbal learning and memory in patients with dementia with Lewy bodies or Parkinson's disease with dementia (2009)

This study compared verbal learning and memory in patients with autopsy-confirmed dementia with Lewy bodies (DLB) and patients with Parkinson's disease with dementia (PDD). A total of 24 DLB patients, 24 PDD patients, and 24 normal comparison participants were administered the California Verbal Learning Test. The three groups were matched on demographic variables, and the two patient groups were matched on the Mattis Dementia Rating Scale. The results indicated that DLB patients recalled less information than PDD patients on all but one recall measure and displayed a more rapid rate of forgetting. In contrast, the PDD patients committed a greater percentage of perseveration errors than the DLB patients. The two groups did not differ in the percentage of recall intrusion errors or any measures of recognition. A discriminant function analysis (DFA) using short-delay cued recall, percentage of perseveration errors, and List B recall differentiated the DLB and PDD groups with 81.3% accuracy. The application of the DFA algorithm to another sample of 42 PDD patients resulted in a 78.6% correct classification rate. The results suggest that, despite equivalent levels of general cognitive impairment, patients with DLB or PDD exhibit a different pattern of verbal learning and memory deficits.
Ferroelectric-driven tunable magnetism in ultrathin platinum films (2020)

Electric control of magnetism in magnetoelectric (ME) multiferroics is expected to have a significant impact on a wide range of technological applications. Here, we predict the modulation of magnetism in ultrathin platinum films due to the ferroelectric polarization of the ${\mathrm{BaTiO}}_{3}$ substrate, which along with biaxial strain changes the density of states at the Fermi energy. We demonstrate that both the magnitude and direction of the magnetization depend strongly on the polarization direction and/or strain. This leads to an unprecedented ME effect involving a giant change of magnetocrystalline anisotropy under polarization switching due to the large spin-orbit coupling of Pt. These findings pave the way of an alternative strategy for the design of nonvolatile and ultralow power spintronics and magnetic memory storage devices.
Hydrogen‐Induced Failure in ZnO Multilayer Ceramic Chip Varistors with a Zinc Phosphate Passivation Layer (2008)

Zinc oxide multilayer ceramic chip varistors (MLVs) with a zinc phosphate passivation layer were studied using electrochemical hydrogen charging, in which hydrogen was deposited on the termination electrodes of MLVs through the electrolysis of water in 0.01 m NaOH solution. The properties of the MLVs remained stable during the first stage of electrochemical hydrogen charging, except that the capacitance was increased slightly. Then a second stage appeared in which the properties of the MLVs were quickly and greatly degraded. The zinc phosphate passivation layer was found to be responsible for producing the first stable stage of electrochemical hydrogen charging. A passivation layer is of great importance to prevent hydrogen‐induced failure for MLVs in service.
Some identities of Laguerre polynomials arising from differential equations (2016)

In this paper, we derive a family of ordinary differential equations from the generating function of the Laguerre polynomials. Then these differential equations are used in order to obtain some properties and new identities for those polynomials.
Simultaneous spin and charge transport in gated Si devices (2011)

Recent advances in the development of techniques for electrical injection and detection of spin-polarized electrons in silicon have aroused intensive research on exploiting devices and circuits that utilize the spin degree of freedom [1–3] as well as electron charge in this dominant material of the semiconductor integrated circuits industry.
Central nicotinic acetylcholine receptor involved in Ca2+‐calmodulin‐endothelial nitric oxide synthase pathway modulated hypotensive effects (2010)

These results suggest that the nAChR-Ca(2+) -calmodulin-eNOS-NO signalling pathway, but not nNOS, plays a significant role in central BP regulation, and neither the ERK1/2 nor Akt signalling pathway are significantly involved in the activation of eNOS by nAChRs in the NTS.
DETECTION OF TRANSGENES IN APPLE ROOTSTOCKS USING ANCHORED PCR (2003)

ISHS XXVI International Horticultural Congress: Biotechnology in Horticultural Crop Improvement: Achievements, Opportunities and Limitations DETECTION OF TRANSGENES IN APPLE ROOTSTOCKS USING ANCHORED PCR
Computational Study on Sensing Properties of Pd‐Decorated Phosphorene for Detecting Acetone, Ethanol, Methanol, and Toluene—A Density Functional Theory Investigation (2021)

Abstract Late reports on the application of black phosphorene for gas sensing have raised great attention to this remarkable 2D material. In this regard, the sensing behavior of phosphorene toward a group of volatile organic compounds (VOCs) is scrutinized. The studied gas molecules are acetone, ethanol, methanol, and toluene as main members of VOCs, along with CO 2 and H 2 O gas molecules. The adsorption of the gases on the pristine and Pd‐decorated phosphorene is studied by employing first‐principles density functional theory (DFT) combined with non‐equilibrium Green's function (NEGF). It is divulged that the selected molecules are weakly adsorbed upon the pristine phosphorene, but after decoration with Pd atom, the adsorption energy, and net charge transfer are improved. It is discovered based on the moderate adsorption energy and large charge transfer for acetone on the Pd‐decorated phosphorene that it can be a suitable sensor for acetone detection. Additionally, recovery time of 2.57 s at the temperature of 350 K, and under ultraviolet (UV) light is achieved after decoration for detection of acetone. Therefore, the authors' theoretical investigations help to better understand the adsorption mechanism of Pd‐decorated phosphorene as a gas sensor and provide a facile approach to broaden its application in industrial, medical, and environmental monitoring.
Texture development and superconducting properties of YBa2Cu3Oxthin films prepared by a solution process in low oxygen partial pressure (2001)

YBa2Cu3Ox (YBCO) thin films on single crystal LaAlO3 substrates were prepared from a trifluoroacetate (TFA) precursor heat treated in a low oxygen partial pressure argon atmosphere. The purpose of the study was to explore the possibility of forming high-purity, epitaxial YBCO films at heat treatment temperatures and oxygen partial pressures low enough to allow the TFA process to be adapted to metallic substrates. The formation of a superconducting YBCO phase was confirmed by measuring the critical temperature (Tc) inductively. In-plane texture and c-axis alignment of the films were determined from x-ray phi scans and omega scans, respectively. Raman microspectroscopy was used to interrogate grain connectivity, oxygen stoichiometry, c-axis verticality with respect to the substrate, and second phase formation. The optimum heat treatment temperature was found to be near 750 °C in an argon atmosphere, the equivalent oxygen partial pressure, which was about 10-5 atm. The full-width half-maxima (FWHMs) of the YBCO (113) phi and (005) omega scans for a sample prepared at 750 °C were about 0.6 and 0.5°, respectively, which indicates that the film was epitaxial. This film showed a sharp superconducting transition at 91 K and an inductive critical current density of 1.3 MA cm-2 at 77 K. The ability to form high-quality YBCO films under the conditions used is consistent with the thermodynamic predictions that the optimal heat treatment temperature decreases as oxygen partial pressure decreases. The results of this study define YBCO formation conditions for TFA-based precursors that may be suitable for application on metallic substrates.
P. 로웰(P. Lowell)의 여행기에 나타난 개화기 조선에 대한 시선과 표상 (2017)

본고에서는 개화기 조선을 방문한 서양인 기록물을 서양의 동양에 대한 인식 체계가 반영된 문화적 산물로 주목하고, 퍼시벌 로웰(Percival Lowell)의 조선 기행문을 분석하여 텍스트 속에 나타난 조선에 대한 외부자로서의 시선과 인식을 탐색하였다. 로웰은 1883년 조미통상수호조약을 계기로 미국에 파견된 보빙사를 보좌한 외국인으로서, 그 임무 수행의...
Sublingual misoprostol versus standard surgical care for treatment of incomplete abortion in five sub-Saharan African countries (2012)

This study has been registered at clinicaltrials.gov as NCT00466999 and NCT01539408.
SoftMAC: layer 2.5 MAC for VoIP support in multi-hop wireless networks (2005)

In this paper, we present the challenges in supporting VoIP services over multi-hop wireless networks using commercial IEEE 802.11 MAC DCF hardware, and propose a novel software solution, called Layer 2.5 SoftMAC. Our proposed SoftMAC resides between the 802.11 MAC layer and IP layer to coordinate the real-time and best-effort packet transmission among neighboring nodes in a multi-hop wireless network. To effectively support VoIP services, our SoftMAC architecture employs three key mechanisms: 1) distributed admission control for regulating the load of real time-traffic, 2) rate control for minimizing the impact of best-effort traffic on real-time traffic, and 3) non- preemptive priority queueing for providing high priority service to VoIP traffic. To evaluate the efficacy of these mechanisms, we conduct extensive simulations using the network simulator NS2. We also implement our proposed SoftMAC as a Windows Network Driver Interface Specification (NDIS) driver over Network Interface Card (NIC) driver, and build a multi-hop wireless network testbed with 32 wireless nodes equipped with 802.11 a/b/g combo cards. Our evaluation and testing results demonstrate the effectiveness of our proposed software solution.
Long‐term fluctuations in volcanic activity: implications for future environmental impact (2009)

Abstract Acidic crater lakes at persistently active volcanoes act as both an index and a moderator of volcanic processes. A catastrophic drop in lake level can therefore lead to serious local environmental damage. In the early 1990s, the crater lake at Poás volcano, Costa Rica diminished, and acid aerosols erupted with devastating consequences for local health, environment and economy. The first indications of this event can be retrospectively identified to have started from 1985, on the basis of our unique 20‐year data time series, which provides evidence for the shallow intrusion of magma. New data presented in this article show similar trends and we conclude that Poás has now entered another active period with renewed intrusion. Severe environmental damage in this region is expected within the next few years if the current trend continues.
Surface Protection and Selective Masking during Diffusion in Silicon (1957)

An apparatus is described for the vapor‐solid diffusion of donors and acceptors into silicon at atmospheric pressure. It consists essentially of a fused silica tube extending through one or more controlled temperature zones. A gas such as nitrogen carries the vapors from the heated impurity element or one of its compounds past the heated silicon.