gebhart/patrepeval huggingface dataset:
Effect of Vaccination with Carrier Protein on Response to Meningococcal C Conjugate Vaccines and Value of Different Immunoassays as Predictors of Protection (2002)

In order to plan for the wide-scale introduction of meningococcal C conjugate (MCC) vaccine for United Kingdom children up to 18 years old, phase II trials were undertaken to investigate whether there was any interaction between MCC vaccines conjugated to tetanus toxoid (TT) or a derivative of diphtheria toxin (CRM(197)) and diphtheria-tetanus vaccines given for boosting at school entry or leaving. Children (n = 1,766) received a diphtheria-tetanus booster either 1 month before, 1 month after, or concurrently with one of three MCC vaccines conjugated to CRM(197) or TT. All of the MCC vaccines induced high antibody responses to the serogroup C polysaccharide that were indicative of protection. The immune response to the MCC-TT vaccine was reduced as a result of prior immunization with a tetanus-containing vaccine, but antibody levels were still well above the lower threshold for protection. Prior or simultaneous administration of a diphtheria-containing vaccine did not affect the response to MCC-CRM(197) vaccines. The immune responses to the carrier proteins were similar to those induced by a comparable dose of diphtheria or tetanus vaccine. The results also demonstrate that, for these conjugate vaccines in these age groups, both standard enzyme-linked immunosorbent assays and those that measure high-avidity antibodies to meningococcal C polysaccharide correlated equally well with assays that measure serum bactericidal antibodies, the established serological correlate of protection for MCC vaccines.
Sustainable Homecare Monitoring System by Sensing Electricity Data (2017)

The ageing of the population has raised the interest in homecare monitoring systems and assisted living in recent years. Most studies pursue non-intrusiveness and scalability to meet the requirements of this ever-growing community. Nonetheless, they are still limited by the technique: wearables need to be carried and sensor networks imply installation. This work presents new solutions to monitor elderlies by using one single sensor: the smart meter or another similar device. This enables a new level of scalability and non-intrusiveness. Likewise, a non-intrusive load monitoring algorithm has been devised to infer the pattern usage of daily used appliances from the total power consumption. These usage patterns have been modeled using Gaussian mixture models and the Dempster-Shafer Theory to create an activity monitoring system that triggers alarms, whenever the subject has deviated from their normal routine.
The Application of Different Tripping Techniques to Determine the Characteristics of the Turbulent Boundary Layer Over a Flat Plate (2017)

In the present study, the optimal two-dimensional (2D) tripping technique for inducing a naturally fully developed turbulent boundary layer in wind tunnels has been investigated. Various tripping techniques were tested, including wires of different diameters and changes in roughness. Experimental measurements were taken on a flat plate in a wind tunnel at a number of locations along the flat plate and at a variety of flow speeds using hot-wire anemometry to measure the boundary layer resulting from each tripping method. The results have demonstrated that to produce a natural turbulent boundary layer using a 2D protuberance, the height of the trip must be less than the undisturbed boundary layer thickness. Using such a trip was shown to reduce the development length of the turbulent boundary layer by approximately 50%. This was shown to hold true for all Reynolds numbers investigated (Rex=1.2×105−1.5×106). The present study provides an insight into the effect of the investigated trip techniques on the induced transition of a laminar boundary layer into turbulence.
Community-Acquired Urinary Tract Infection byEscherichia coliin the Era of Antibiotic Resistance (2018)

Urinary tract infections (UTIs) caused by <i>Escherichia coli (E. coli)</i> are the most common types of infections in women. The antibiotic resistance of <i>E. coli</i> is increasing rapidly, causing physicians to hesitate when selecting oral antibiotics. In this review, our objective is to ensure that clinicians understand the current seriousness of antibiotic-resistant <i>E. coli</i>, the mechanisms by which resistance is selected for, and methods that can be used to prevent antibiotic resistance.
Dense Polytetrafluoroethylene Membrane versus Titanium Mesh in Vertical Ridge Augmentation: Clinical and Histological Results of a Split-mouth Prospective Study (2021)

Both d-PM and TM can be used to augment atrophic localized ridges vertically. The outcome of bone regeneration seems to be impaired by exposure of the device. How to cite this article: Maiorana C, Fontana F, Rasia dal Polo M, <i>et al</i>. Dense Polytetrafluoroethylene Membrane versus Titanium Mesh in Vertical Ridge Augmentation: Clinical and Histological Results of a Split-mouth Prospective Study. J Contemp Dent Pract 2021;22(5):465-472.
The Wolfsberg Anti‐Money Laundering Principles (2001)

On 30th October, 2000, a new initiative to combat money laundering was unveiled. What differentiates this initiative from many of the existing initiatives is that it has been put forward by the private sector. Eleven banks signed a set of principles known as the Wolfsberg Anti‐Money Laundering Principles (the ‘Wolfsberg Principles’). The Wolfsberg Principles are a non‐binding set of best practice guidelines governing the establishment and maintenance of relationships between private bankers and clients. Over the past decade much has been written about money laundering, the problems it creates for the economic, political and social institutions of countries, and the need to combat the phenomenon. Most initiatives to date have been public sector led by governments and their regulatory and law enforcement agencies, or by government representatives acting through international forms such as the Financial Action Task Force (FATF) and the Basel Committee of Bank Supervisors. Consequently, most initiatives have focused on enacting new criminal laws, implementing reporting requirements, and developing codes of best practice. The fact that the private sector has taken the initiative to establish the Wolfsberg Principles is therefore worthy of closer analysis. As Dr Peter Eigen, the Chairman of Transparency International, observed on the release of the Wolfsberg Principles, ‘This is a unique event — few would expect the leading anti‐corruption organisation and the leading banks to be standing on the same platform’. The following article examines the Wolfsberg Principles in order to identify the various strengths and weaknesses of each. First, however, it is worth noting in brief the background to the Wolfsberg Principles and the regulatory paradigm within which they are to operate.
Abnormal VIII: von Willebrand factor patterns in the plasma of patients with the hemolytic-uremic syndrome (1984)

Plasma VIII:von Willebrand factor antigen (VIII:vWF) levels were elevated approximately two- to eightfold in seven patients (three adults and four children) during acute episodes of thrombocytopenia, renal failure, and hemolytic anemia (the hemolytic-uremic syndrome, HUS). In all seven patients, there was an alteration in plasma VIII:vWF patterns during these acute HUS episodes, so that the largest VIII:vWF forms were relatively decreased. Plasma VIII:vWF multimer patterns returned to normal, or nearly to normal, as platelet counts returned to preexisting levels, even in the patients whose recovery of renal function was incomplete and whose plasma VIII:vWF antigen level remained above normal. The sister of one of the HUS patients had a similar clinical prodrome (gastroenteritis) that was not followed by thrombocytopenia or renal failure and was not accompanied by an elevated level or abnormal forms of plasma VIII:vWF. These results suggest that an alteration in VIII:vWF metabolism, distribution, or interaction with platelets is associated with acute HUS episodes. In contrast to patients with chronic relapsing thrombotic thrombocytopenic purpura, none of the HUS patients (either during or after the acute HUS episodes) had a defect in the conversion of unusually large VIII:vWF multimers derived from endothelial cells to the VIII:vWF forms found in normal plasma.
Construction and Evaluation of an Optical Medium Voltage Transducer Module Aimed at a 132 kV Optical Voltage Sensor for WAMPAC Systems (2022)

This paper reports on the construction and characterization of an optical voltage transducer module for applications in the field of wide-area monitoring, protection, and control (WAMPAC). The optical medium voltage transducer (MVT) module was designed to be combined with a capacitive voltage divider (CVD) to form a voltage sensor intended for 132 kV high voltage (HV) networks. The MVT module comprises a combination of a piezoelectric transducer (PZT) and a fiber Bragg grating (FBG) as a core optical sensing element. Changes in the input voltage across the PZT translate into strain being detected by the FBG. The resultant FBG peak wavelength can be calibrated in terms of the input voltage to obtain a precise voltage measurement. The module was experimentally evaluated in the laboratory, and its performance was assessed based on the requirements specified by the IEC standards for electronic voltage transformers and low power voltage transformers. The results of accuracy tests demonstrate that the MVT module is free from hysteresis, within the experimental error, and is capable of simultaneously meeting the requirements for 0.1 metering and 1P protection classes specified by the IEC 60044-7 and IEC 61869-11 standards.
313.5: Meeting Packed Red Blood Cell Requirement for the Transmedics Organ Care System (OCS) Liver Transplantation Trial (PROTECT Trial) At Henry Ford Hospital (2022)

Introduction: In January 2016, HFHS Transplant Institute began the PROSPECT trial, an interventional trial studying normothermic preservation of the donated liver before transplant using the Liver Organ Care System (OCSTM). The Henry Ford Hospital Transfusion Service (TS) provided the required packed red blood cells (PRBC). Background: The TransMedics (OCSTM) liver trial was an international, randomized trial studying the intervention of a portable liver system to preserve donor livers for transplant. The system utilizes an oxygenated blood-based perfusate mixed with nutrient solution in normothermic perfusion for organ preservation. The TS provided PRBC needed for the study, final PRBC used dictated by the condition and size of the retrieved liver. TS study goal was to secure proper transfusion needs for liver perfusion while also adhering to blood inventory management. Methods: Organ procurement candidates for the PROTECT trial were selected based on pre-determined conditions and consented according to that protocol. Once the patient was consented and the liver transplantation was scheduled, the PROTECT trial team notified the TS,and 5 units of group O Positive, leukoreduced PRBC less than 10 days old were selected, and placed inside a temperature-controlled packaging container along with a remote temperature monitoring device. The container was then transported with the procurement team to the harvesting location. Once the insulated container was returned to the TS, the temperature-monitoring device information was uploaded to verify that the returned PRBC have been stored within their proper temperature limits. Results: The TS support for the PROTECT trial at HFHS occurred from January 2016 until September 2021. The table below shows the activity related to this trial. - Issued Utilized Returned Wasted PRBC units 240 132 104 4 In summary, 29/48 study events used 4 units; 3/48 study events used 5 units; on 15/48 events the organ harvesting was cancelled; all units returned had an acceptable temperature range and returned to the available inventory. For one study event, 4 PRBC were spiked in preparation for use in the perfusate prior to the event being cancelled. These PRBC were discarded and deemed wasted. Conclusions: During the PROTECT trial no PRBCs were wasted due to inappropriate storage conditions. The joint use of a temperature-controlled container and remote temperature monitoring device allowed for the appropriate return of unused PRBCs to the TS blood inventory, thus avoiding any wastage. Only 3/48 events used 5 units, the\us issuing 4 PRBC to meet the OCS™ support may suffice, further decreasing the risk for wastage of any PRBC units. After receiving FDA in September 2021, alternatives to maintain the required PRBC temperature should be addressed to minimize wastage at this time of limited blood availability for the support of the TransMedics Organ Care System (OCSTM) for liver organ perfusion.
Application of Radio-Frequency Discharged Plasma Produced in Closed Magnetic Neutral Line for Plasma Processing (1994)

A new plasma processing method is presented. Use of plasma produced in a closed magnetic neutral line is essential and the merit is easily illustrated in principle with a preliminary experimental result. This method is considered to be useful for many kinds of plasma processing.
Novel Applications of Neural Networks in Speech Technology Systems: Search Space Reduction and Prosodic Modeling (2009)

Abstract Neural networks (NNs) have been extensively used in speech technology systems. In this paper, we present two novel applications of NNs in speech recognition and text-to-speech systems. The prosodic modeling is one of the most important tasks for developing a new text-tospeech synthesizer, especially in a female-voice high-quality restricted-domain system. Our double objective is to get accurate predictors for both the fundamental frequency (FO) curve and phoneme duration by minimizing the model estimation error in a Spanish text-to-speech system, by means of a neural network estimator, which has proved to be an excellent tool for the modeling. The resulting system predicts prosody with very good results (for duration: 15.5 ms in RMS and a correlation factor of 0.8975; for F0: 19.80 Hz in RMS and a relative RMS error of 0.43) that clearly improves our previous rule-based system.
Correlation Between Sea Urchin Sperm Respiratory Rates and Cyclic AMP Concentrations as a Function of Cell Dilution1 (1978)

The adenosine 3′,5′-monophosphate (cyclic AMP) levels and respiration rates of Strongylocentrotus purpuratus and Lytechinus pictus sea urchin sperm were estimated after various degrees of cell dilution. Dilution of L. pictus sperm caused substantial increases in both sperm cyclic AMP levels and respiratory rates. In contrast to L. pictus sperm, cyclic AMP levels and respiratory rates were elevated only slightly by dilution of S. purpuratus sperm. These results provide evidence for a positive relationship between endogenous cyclic AMP levels and respiratory rates in sea urchin spermatozoa.
Repression of the Human Papillomavirus E6 Gene Initiates p53-Dependent, Telomerase-Independent Senescence and Apoptosis in HeLa Cervical Carcinoma Cells (2004)

Cervical cancer cells express high-risk human papillomavirus (HPV) E6 and E7 proteins. When both HPV oncogenes are repressed in HeLa cervical carcinoma cells, the dormant p53 and retinoblastoma (Rb) tumor suppressor pathways are activated, and the cells undergo senescence in the absence of apoptosis. When the E6 gene is repressed in cells that continue to express an E7 gene, the p53 pathway, but not the Rb pathway, is activated, and both senescence and apoptosis are triggered. To determine the role of p53 signaling in senescence or apoptosis after repression of HPV oncogenes, we introduced a dominant-negative allele of p53 into HeLa cells. Dominant-negative p53 prevented senescence and apoptosis when E6 alone was repressed but did not inhibit senescence when both E6 and E7 were repressed. To determine whether reduced telomerase activity was involved in senescence or apoptosis after E6 repression, we generated HeLa cells stably expressing an exogenous hTERT gene, which encodes the catalytic subunit of telomerase. Although these cells contained markedly elevated telomerase activity and elongated telomeres, hTERT expression did not prevent senescence and apoptosis when E6 alone was repressed. These results demonstrate that when the Rb tumor suppressor pathway is inactivated by the E7 protein, E6 repression activates p53 signaling, which in turn is required for growth inhibition, senescence, and apoptosis. Thus, sustained inactivation of the p53 pathway by the E6 protein is required for maintenance of the proliferative phenotype of HeLa cervical carcinoma cells.
Enantioselective reduction of ketones with triethoxysilane catalyzed by chiral bis-oxazoline titanium complexes (1999)

Chiral bis-oxazoline titanium complexes [Ti(BOX)2X2] prepared from C2 chiral bis-oxazolines, BuLi and titanium salts, catalyze the enantiosective reduction of ketones in the presence of triethoxysilane.
Contributions of Inter- and Intraband Excitations to Electron Heat Capacity and Electron-Phonon Coupling in Noble Metals (2009)

This work examines the effects of photonically induced interband excitations from the d-band to states at the Fermi energy on thermophysical properties in noble metals. The change in the electron population in the d-band and the conduction band causes a change in electron heat capacity and electron-phonon coupling factor, which in turn impacts the evolution of the temperature after pulse absorption and electron thermalization. Expressions for heat capacity and electron-phonon coupling factor are derived for electrons undergoing both inter- and intraband transitions. In noble metals, due to the large d-band to Fermi energy separation, the contributions to electron heat capacity and electron-phonon coupling factor of intra- and interband transitions can be separated. At high absorbed laser fluences and pulse energies greater than the interband transition threshold, the interband and intraband contributions to thermophysical properties differ.
Color Restoration of RGBN Multispectral Filter Array Sensor Images Based on Spectral Decomposition (2016)

A multispectral filter array (MSFA) image sensor with red, green, blue and near-infrared (NIR) filters is useful for various imaging applications with the advantages that it obtains color information and NIR information simultaneously. Because the MSFA image sensor needs to acquire invisible band information, it is necessary to remove the IR cut-offfilter (IRCF). However, without the IRCF, the color of the image is desaturated by the interference of the additional NIR component of each RGB color channel. To overcome color degradation, a signal processing approach is required to restore natural color by removing the unwanted NIR contribution to the RGB color channels while the additional NIR information remains in the N channel. Thus, in this paper, we propose a color restoration method for an imaging system based on the MSFA image sensor with RGBN filters. To remove the unnecessary NIR component in each RGB color channel, spectral estimation and spectral decomposition are performed based on the spectral characteristics of the MSFA sensor. The proposed color restoration method estimates the spectral intensity in NIR band and recovers hue and color saturation by decomposing the visible band component and the NIR band component in each RGB color channel. The experimental results show that the proposed method effectively restores natural color and minimizes angular errors.
TEMPORARY BARRIERS USED IN CONSTRUCTION ZONES (1980)

In and around highway construction zones, delineation devices as well as barriers are used to control and restrict the flow of traffic. The need for positive, containing barriers was recognized by the Federal Highway Administration (FHWA). The FHWA further recognized that many temporary barrier devices were being used without documented performance. Accordingly, four temporary barriers were selected for crash test evaluation: (1) 25x25 cm(10x10) timber barrier; (2) W-beam/barrel barrier; (3) Type X curb; (4) Stacked timber barrier. These barriers were subjected to controlled impacts with full size 2040-kg (4500-lb) cars impacting at angles from 7 to 15 degrees at speeds from 56 km/h (35 mph) to 90 km/h (56 mph). Results indicate the first and third barrier designs had minimal redirection/containment capacity, and performance was judged to be poor. The W-beam/barrel concept performed well during a 72 km/h (45 mph), 15-deg angle impact, but performance was unsatisfactory for 55 mph (88 km/h), 15-deg angle. The stacked timber barrier provided smooth redirection for both 35 mph (56 km/h) and 50 mph (80 km/h) impacts. (FHWA)
Sliding‐mode position control of medium‐stroke voice coil motor based on system identification observer (2015)

This study presents the performance improvement in the position control of a medium‐stroke voice coil motor (VCM) using a sliding‐mode controller (SMC) with a system identification observer (SIO). The proposed VCM is developed with a full stroke of 24 mm, and its non‐linear electro‐magneto‐mechanical characteristics are analysed by the three‐dimensional finite element method. A least‐squares‐based SIO is introduced into the VCM control system prior to the position regulation of the SMC in order to achieve a shorter rise time of 29 ms and a smaller steady‐state error of &lt;±2 μm under a square‐wave excitation of 20 mm amplitude and 0.5 Hz frequency. An experimental verification between the SMC and a traditional proportion–integral–differential controller is carried out. The results demonstrate improved dynamic and static tracking responses in the SMC under load‐free, frequency‐varying operations.
Quan les dones van trencar les cotilles literàries (2018)

A proposit de l'apariacio de dones escriptores a Catalunya i a Espanya abans de la guerra civil espanyola.
Supplementary Figure S5 from Identification of Rare High-Avidity, Tumor-Reactive CD8<sup>+</sup> T Cells by Monomeric TCR–Ligand Off-Rates Measurements on Living Cells (2023)

&lt;p&gt;Supplementary Figure S5. Impact of rapid association on-rates on cell surface dissociation kinetics by reversible NTAmers.&lt;/p&gt;
Publisher Correction: Non-invasive assessment of hepatic mitochondrial metabolism by positional isotopomer NMR tracer analysis (PINTA) (2018)

The originally published version of this Article contained an error in Equation 30, which was inadvertently introduced during the production process. This has now been corrected in the PDF and HTML versions of the Article.