gebhart/patrepeval huggingface dataset:
Multifeature object tracking using a model-free approach (2002)

In this paper we introduce a new model-free method for object tracking. The tracking is posed as a segmentation problem which we solve using the watershed algorithm. A framework is defined to compute the required topographic surface from distances to the predicted contour intensity, edges and motion edges. This multifeature tracking approach yields accurate results in the presence of object corners, image clutter and camera motion. Results on real sequences confirm the stability and robustness of the method. Objects are tracked over long sequences and in the presence of fast object motion.
Interleukin-1 signaling pathway as a therapeutic target in transthyretin amyloidosis (2014)

The present work highlights the relevance of the IL-1 signaling pathway in the pathophysiology of FAP. Our results bring to light the importance of non-amyloid targets in the therapeutic strategies for this disorder. Thus, we propose the use of Anakinra as a potential therapeutic agent for TTR-related amyloidosis.
P-383 A new function to detect and analyze activity status in paced patients (2003)

The aim of this study was to determine the impact of right heart dimensions on long term atria1 sensing stability (ASS) in VDD implanted patients@ts).
Deformation-tracking impedance control in interaction with uncertain environments (2013)

A deformation-tracking impedance control strategy is discussed for applications where a manipulator interacts with environments of unknown geometrical and mechanical properties, especially with stiffness comparable to a controlled robot stiffness. Based on force-tracking impedance controls, the deformation-tracking strategy allows the control of a desired deformation of the target environment, requiring the on-line estimation of the environment stiffness. An Extended Kalman Filter is used for the estimation of the environment because of measurement uncertainties and errors in compound interaction model. The tasks presented involve full body spatial interactions with a time-varying environment stiffness. The Extended Kalman Filter and the deformation-tracking impedance control are validated in simulation and with experiments. In particular, a cooperative assembly task is also performed with a human operator acting as varying environment, i.e. unpredictably changing the handling arm stiffness.
Irán. Cuatro años más de Ahmadineyad (2009)

Tras la orden de ratificacion de Ali Jamenei, guia supremo del pais, el candidato ultra renueva su mandato en medio de la polemica por fraude electoral
Shear strength of unchecked glued-laminated beams (1994)

The allowable stress in shear is derived from shear tests of small clear shear blocks, but the shear strength of shear blocks is much greater than the shear strength of larger beams. In this study, glued-laminated beams were tested to determine shear strength. These specimens were tested in the five-point bending test configuration. Shear blocks were cut from the beam after failure and tested for shear strength. From these tests, a relationship between shear strength and beam size was developed that uses American Society for Testing and Materials (ASTM) shear block strength as a basis. The recommended relationship is based on test results for a number of sizes of Douglas-fir and southern pine unchecked glued-laminated beams (...)
Physical and Instrumental Considerations in the Use of Lithium Phthalocyanine for Measurements of the Concentration of the Oxygen (1994)

The use of crystals of lithium phthalocyanine (LiPc) to measure the concentration of oxygen in vivo and in vitro by electron paramagnetic resonance leads to experimental constraints due to the very narrow EPR lines that may occur (as narrow as 11-13 mG in the absence of O2), distortions induced by the automatic frequency control system, anisotropy in the spectra (orientation-dependent linewidth is 11-17 mG in the absence of O2), microwave power saturation, and the effect of physiological motion. These constraints can be overcome if recognized. This article highlights the experimental and theoretical basis of these properties of the EPR signal of LiPc and suggests some technical solutions. It is most important to recognize that paramagnetic species such as LiPc present problems that are not commonly encountered in EPR spectroscopy.
Analyses of the DC-Link Current in Discontinuous Modulated Three-Phase Inverters (2006)

For reduction of the switching power losses developer of three-phase inverters thinks increasingly about discontinuous modulation strategies. This applies in particular for high power inverters such as for starter generator - or hybrid drive systems. The dc-link current of these discontinuous modulated voltage source inverter are analyzed in this paper. First the dc- and the rms-current of the dc-link circuit are calculated depending on the phase shift angle and the modulation factor. Afterwards the current harmonics of the dc-link circuit for a defined phase shift angle and modulation factor are determined. The calculations are verified by several circuit simulations.
Innovations in fixed-field accelerators: Design and simulation (2010)

The drive for higher beam power, high duty cycle, and reliable beams at reasonable cost has focused world attention on fixed-field accelerators, notably a broad class of accelerators termed Fixed-field Alternating Gradient accelerators, or FFAGs, (with cyclotrons considered a specific expression or sub-class of FFAGs). Recently, the concept of isochronous orbits has been explored and developed for the most general type of FFAG (termed nonscaling) using powerful new methodologies in fixed-field accelerator design. One application is high-intensity, in particular high-energy (GeV), proton drivers which encounter duty cycle and space-charge limits in the synchrotron and machine size concerns in the weakerfocusing cyclotrons. With isochronous orbits, FFAGs are capable of the high duty cycle, or CW operation, associated with cyclotrons. Further, their strong focusing enables smaller losses, and potential energy variability that are more typical of the synchrotron. With the cyclotron as the current industrial and medical standard, a competing CW FFAG, could potentially have broad impact on research, industrial, and medical accelerators and associated facilities. This paper reports on new advances in FFAG accelerator technology, design, and simulation, and also presents advanced tools developed for all fixed-field accelerators unique to the code COSY INFINITY[1].
Effect of ionization rates on dynamic recovery processes during electron-beam irradiation of 6H-SiC (2007)

The authors have investigated the effects of 200 and 300keV electron-beam irradiations on amorphization in 6H-SiC at 100 and 295K. Amorphization is induced by the accumulation of defects produced by direct atomic displacements. Dynamic recovery of these defects during irradiation, due to temperature increases and ionization effects, results in increases in the amorphization dose. By comparing with previous data for 2MeV electrons and 1.5MeV Xe ions, the results demonstrate that ionization-enhanced recovery in 6H-SiC dramatically increases above an ionization rate threshold.
Simultaneous segmentation and tree reconstruction of the airways for virtual bronchoscopy (2002)

During the last couple of years virtual endoscopic systems (VES) have emerged as standard tools that are nowadays close to be utilized in daily clinical practice. Such tools render hollow human structures, allowing a clinician to visualize their inside in an endoscopic-like paradigm. It is common practice that the camera of a virtual endoscope is attached to the centerline of the structure of interest, to facilitate navigation. This centerline has to be determined manually or automatically, prior to an investigation. While there exist techniques that can straightforwardly handle simple tube-like structures (e.g. colon, aorta), structures like the tracheobronchial tree still represent a challenge due to their complex branching. In these cases it is necessary to determine all branching points within the tree which is - because of the complexity - impractical to be accomplished in a manual manner. This paper presents a simultaneous segmentation/skeletonization algorithm that extracts all major airway branches and large parts of the minor distal branches (up to 7th order) using a front propagation approach. During the segmentation the algorithm keeps track of the centerline of the segmented structure and detects all branching points. This in turn allows the full reconstruction of the tracheobronchial tree.
ChemInform Abstract: The Synthesis of O‐Silyl Ketene Acetals from α‐Halo Esters. (1989)

Abstract The title compounds (III) are prepared from the α‐halo esters (Ia) ‐ (Ie) by reaction with sodium and chlorotrimethylsilane (II).
Proliferative glomerulonephritis and primary antiphospholipid syndrome. (2006)

Little is known regarding the association of primary antiphospholipid syndrome APLS and proliferative glomerulonephritis GN. We describe a biopsy-documented case with primary APLS and proliferative GN with no evidence of thrombotic microangiopathy TMA, and in the absence of other manifestations of systemic lupus erythematosus SLE. She presented initially with left popliteal deep venous thrombosis and nephrotic syndrome. Her first pregnancy at the age of 26 years resulted in intra-uterine fetal death at term. Two subsequent pregnancies ended up with miscarriages at 3 and 4 months of gestation. Urinalysis revealed glomerular red blood cells of 1.0000.000/ml and granular cast; proteinuria of 13.4 grams/24 hours, which was non-selective; hemoglobin 12 gm/dl, normal white blood cell and platelets; serum albumin 2.6 gm/dl; anti-nuclear antibody ANA and anti DNA were negative and complement levels normal. Lupus anticoagulant was positive leading to a diagnosis of primary APLS. The biopsy findings were consistent with membranoproliferative GN. She continued to have steroid-resistant proteinuria, but stable renal function after a 12-year follow up period. She had 2 pregnancies during this period and was delivered at term using caesarian section. She received heparin during the pregnancies. Later she developed hypertension easily controlled by atenolol. This case provides evidence that primary APLS can be associated with proliferative GN due to immune deposits and not only TMA as previously reported, and in the complete absence of SLE. Performing more renal biopsies in this group of patients may disclose a greater prevalence of proliferative GN and may help in devising a rationale for treatment.
Abstract 20609: Abnormalities of Mitochondrial Number and Function in Pediatric Idiopathic Dilated Cardiomyopathy (2014)

Introduction: Impaired mitochondrial energy production and substrate utilization have been implicated in the development of heart failure (HF) in adults. Little literature exists describing mitochondrial energetics in pediatric HF. We have previously shown that content of Cardiolipin (CL), a major mitochondrial membrane phospholipid, is depleted in both adult and pediatric idiopathic dilated cardiomyopathy (IDC), with preserved expression of mitochondrial-encodes genes. Similar CL changes occur in a rat model of HF with associated mitochondrial dysfunction that precedes myocardial dysfunction, which can be reversed by dietary interventions. Hypothesis: We hypothesize that mitochondrial dysfunction occurs in pediatric IDC. Methods: As a part of an on-going study a cross-sectional analysis of mitochondrial content and function was performed in left ventricle tissue from the University of Colorado Pediatric Heart Tissue Bank. Current contents: age 13-18: 11 IDC (64% male) and 13 NF (62% male). All NF are donor hearts with normal LVEF; all IDC specimens had LVEF &lt;30%. Results: We show lower mitochondrial copy number in pediatric IDC compared with NF controls (IDC: 44 vs NF: 24, P&lt;0.05), with paradoxical up-regulation of transcriptional co-activators, PGC1α and NRF1 (P&lt;0.01). This is in contrast to what has been shown in adult HF where PGC1α and NRF1 expression are unchanged. Electron transport chain (ETC) complex enzymatic activities were quantified in a sub-group of pediatric IDC samples, expressed as Z-scores relative to normative values in 18 NFs. Significantly decreased activities of complexes I, IV, and citrate synthase were found (Z-scores -2.2, -3.3 and -1.7 respectively), with a significant increase in complex III activity (Z-score 0.7, all P&lt;0.05). Conclusions: These results suggest impaired mitochondrial biogenesis occurs in pediatric HF by a unique mechanism from that seen in adults. Additionally, we show a very specific pattern of ETC dysfunction in pediatric IDC. Future studies will identify the how decreased mitochondrial copy number occurs in the context of PGC1α and NRF1 up-regulation and determine whether abnormalities in CL contribute to abnormalities in ETC activities.
Estimation of uncertainty in multivariate vibrational spectroscopy (1995)

The work reported illustrates an approach to the estimation of uncertainty in multivariate vibrational spectroscopic data. The definition and theory of uncertainty used is derived from the individual contributions to uncertainties. The approach adopted involves the characterization and modelling of random effects in infrared spectroscopic data. Spectral phenomena present in the data were described by models of uncertainty. These models were subsequently collated and used successfully for the predictions of sample concentrations, supplementing them with data on estimated uncertainty. Further, the selectivity of the data and the wavelength combination in terms of minimal and optimal sensors, were also calculated and shown to be influencing the uncertainty of concentration estimates. The relationship between selectivity and uncertainty was investigated and the dependence was shown to be an inverse linear function. Finally, the calibration approach employed was shown to be largely independent of the effects of smoothing.
Engineering Analysis of Shape Change in Zinc Secondary Electrodes: I . Theoretical (1976)

Shape change, the redistribution of active material over the zinc electrode surface as a result of cell cycling, is hypothesized to be caused by convective flows driven primarily by membrane pumping. A mathematical model is formulated based on the convective flow hypothesis for the zinc‐silver oxide secondary cell. The numerical solutions predict redistribution of zinc material over the zinc electrode, fluid flow rates, and variations of current distribution and cell potential with the number of cycles. These calculated results can be compared to experimental results. The results suggest that shape change can be eliminated if the convective flow in the zinc electrode compartment parallel to the electrode surface is stopped.
Prospective study of ultraviolet radiation exposure and risk of cancer in the United States (2012)

Ecologic studies have reported that solar ultraviolet radiation (UVR) exposure is associated with cancer; however, little evidence is available from prospective studies. We aimed to assess the association between an objective measure of ambient UVR exposure and risk of total and site-specific cancer in a large, regionally diverse cohort [450,934 white, non-Hispanic subjects (50-71 years) in the prospective National Institutes of Health (NIH)-AARP Diet and Health Study] after accounting for individual-level confounding risk factors. Estimated erythemal UVR exposure from satellite Total Ozone Mapping Spectrometer (TOMS) data from NASA was linked to the US Census Bureau 2000 census tract (centroid) of baseline residence for each subject. We used Cox proportional hazards models adjusted for multiple potential confounders to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for quartiles of UVR exposure. Restricted cubic splines examined nonlinear relationships. Over 9 years of follow-up, UVR exposure was inversely associated with total cancer risk (N = 75,917; highest versus lowest quartile; HR = 0.97, 95% CI = 0.95-0.99; p-trend < 0.001). In site-specific cancer analyses, UVR exposure was associated with increased melanoma risk (highest versus lowest quartile; HR = 1.22, 95% CI = 1.13-1.32; p-trend < 0.001) and decreased risk of non-Hodgkin's lymphoma (HR = 0.82, 95% CI = 0.74-0.92) and colon (HR = 0.88, 95% CI = 0.82-0.96), squamous cell lung (HR = 0.86, 95% CI = 0.75-0.98), pleural (HR = 0.57, 95% CI = 0.38-0.84), prostate (HR = 0.91, 95% CI = 0.88-0.95), kidney (HR = 0.83, 95% CI = 0.73-0.94) and bladder (HR = 0.88, 95% CI = 0.81-0.96) cancers (all p-trend < 0.05). We also found nonlinear associations for some cancer sites, including the thyroid and pancreas. Our results add to mounting evidence for the influential role of UVR exposure on cancer.
Critical roles for IL-4, IL-5, and eosinophils in chronic skin allograft rejection (1999)

C57BL/6 mice injected with the 145-2C11 anti-CD3 mAb and grafted with MHC class II disparate bm12 skin develop a chronic rejection characterized by interstitial dermal fibrosis, a marked eosinophil infiltrate, and an obliterative intimal vasculopathy. Because these changes occur in the absence of alloreactive antibodies, we examined the contribution of cytokines in their pathogenesis. Chronically rejected grafts showed a marked accumulation of both IL-4 and IL-5 mRNA. Mixed lymphocyte reaction experiments established that mice undergoing chronic rejection were primed for IL-4, IL-5, and IL-10 secretion. In vivo administration of anti-IL-4 mAb completely prevented allograft vasculopathy as well as graft eosinophil infiltration and dermal fibrosis. Injection of anti-IL-5 mAb or the use of IL-5-deficient mice as recipients also resulted in the lack of eosinophil infiltration or dermal fibrosis, but these mice did develop allograft vasculopathy. Administration of anti-IL-10 mAb did not influence any histologic parameter of chronic rejection. Thus, in this model, IL-4- and IL-5-mediated tissue allograft eosinophil infiltration is associated with interstitial fibrosis. IL-4, but not eosinophils, is also required for the development of obliterative graft arteriolopathy.
Monorail™ Piccolino catheter: A new rapid exchagne/ultralow profile coronary angioplasty system (1990)

The Monorail Piccolino coronary angioplasty balloon catheter (MBC) was evaluated on 118 patients at two centers. Technical success was achieved in 110 patients (93%). Time for catheter exchange and total fluoroscopy time were significantly lower for the Monorail catheter than with standard equipment (exchange time 97 vs. 170 seconds P less than .05 and fluoroscopy time 17 vs. 88 seconds P less than .001). The advantages of rapid exchange and the ability of utilize 2 Monorail balloon catheters through one 9F guiding catheter for simultaneous inflations allowed for maximal flexibility in treating patients with bifurcation lesions. The double wire approach utilizing one Monorail balloon catheter with a 7F guiding catheter was also technically successful. The Monorail Piccolino balloon catheter has unique features that allow for greater ease of operator use, rapid catheter exchange, and optimal angiographic visualization. It is felt that this catheter design provides distinct advantages over standard angioplasty equipment.
The Impact of Matrix Metalloproteinases and Their Tissue Inhibitors in Inflammatory Bowel Diseases (2012)

We demonstrated that serum antigen concentrations of MMP-9, TIMP-1 and TIMP-2 were significantly increased in patients with UC and CD compared to controls. Our results suggest that MMPs and TIMPs may contribute to the inflammatory and remodeling processes in IBD. Serum MMP-9 and TIMP-1 might be useful as additional biomarkers in the assessment of IBD activity.
Reliability for "Future" Devices (2008)

This article consists of a collection of slides from the author's conference presentation. Some of the specific areas/topics discussed include: Scaling (Density & Materials); Si Devices (Planar Devices: Classical, Fully depleted), (Non planar Devices: Non-Si Devices: Ge & III/V, and 1D devices); and a Summary.
Subclinical Cerebral Edema in Children With Diabetic Ketoacidosis Randomized to 2 Different Rehydration Protocols (2012)

ADC changes during DKA treatment (reflective of vasogenic CE) do not appear to be substantially affected by the rate of intravenous fluid administration.
Trait hostility and ambulatory blood pressure among traffic enforcement agents: The effects of stressful social interactions. (2009)

This study investigated the hypothesis that trait hostility is associated with heightened cardiovascular reactivity to potentially stressful social interactions but not to nonsocial activities in the workplace. Participants were 73 (39 women) New York City traffic enforcement agents (TEAs) who patrol the streets and issue summonses for vehicular and parking violations. During their patrols, TEAs face potentially stressful interactions when they encounter motorists and pedestrians who may be angry about receiving summonses. Mood and ambulatory blood pressure were initially measured when TEAs were recently hired and attending classes at the training academy (Time 1), and were subsequently assessed again once the TEAs began independently patrolling the city streets (Time 2). Random effects regression models yielded a significant interaction of hostility and work activity on ambulatory systolic blood pressure at Time 2. For those high in hostility, but not for those low in hostility, systolic blood pressure levels were higher while interacting with members of the public than during nonsocial work activities. The findings support the notion that situational factors affect the association of hostility to cardiovascular reactivity, and that interpersonal stressors in the workplace elicit cardiovascular activation among those high in hostility.
Accommodationists versus structuralists : some empirical evidence from Spain (1987-98) (1999)

The main purpose of the study is to test empirically the theoretical controversy between the so-called accommodationist and approaches in the context of the endogenous money hypothesis. The former is usually summarised as stating that the determination of the money supply is essentially both credit-driven and demand- determined. The information used for empirical testing corresponds to monetary time series data from the Spanish economy covering the period 1987-1998. It thus encompasses the period which stretches from the complete liberalisation of commercial banks deposit and lending rates in Spain up to the passing over of monetary policy management from the Bank of Spain to the European Central Bank. Direct Granger causality tests are then run between the monetary base, various money multipliers (using the M1, M2 and M3 definitions) and bank lending to the non-bank private sector for the period considered. Overall the results lend strong support for the structuralist approach since Granger causality is found to run predominantly from bank lending to the monetary base (and thus banks´ reserves) and the various money multipliers.
Model-based system assessment and trajectory optimization on aircraft level (2015)

The quantification of aircraft level benefits like the reduction of mass, drag, power offtake, and consequently fuel burn is a key aspect in assessing new technologies like green taxiing systems, electrical environmental control systems, and optimized aircraft trajectories. A basic means to determine these deltas is a detailed dynamic model of the aircraft containing the flight dynamics, kinematics, aerodynamics, engine behaviour and emissions as well as systems for ground operations. This paper shows the principles of this model-based approach and gives quantitative results with respect to fuel consumption, NOx and noise emission for two examples, a trajectory optimization case and an electric drive system for taxiing without main engines. This kind of model-based approach can be extended to the assessment of new technologies in a realistic, everyday operational situation, ultimately helping stakeholders in the decision whether adopting innovations in a specific operational case.