gebhart/patrepeval huggingface dataset:
Nutzung von ZfP-Daten bei der Nachrechnung von Brücken - Beispiel Regenbrücke Roding (2020)

Im Laufe des Lebenszyklus einer Brucke kann es erforderlich sein, diese hinsichtlich der Tragfahigkeit neu zu bewerten. Ursachlich hierfur sind beispielsweise sich andernde Einwirkungen, wie steigende Verkehrslasten oder auch neuere Erkenntnisse, die beim ursprunglichen Bauwerksentwurf noch nicht berucksichtigt wurden. Die aufgefuhrten Ursachen treten hierbei meisten nach mehreren Jahrzehnten der Nutzung des Bauwerkes auf.
In Deutschland findet eine planmasige Neubewertung fur Bruckenbauwerken des Bundes und der Lander auf Basis der im Mai 2011 eingefuhrten Nachrechnungsrichtline statt. Neben der Neubewertung zur Gewahrleistung der Zuverlassigkeit im laufenden Betrieb ist es insbesondere im Rahmen des Abbruches von Bauwerken wichtig Resttragfahigkeiten beurteilen zu konnen.
Die Zuverlassigkeit der Berechnungsergebnisse hangt insbesondere von der Anzahl und von der Qualitat der einbezogenen Informationen ab. Durch die Anwendung von zerstorungsfreien Prufmethoden konnen quantitative Informationen gesammelt werden, die fur die Beurteilung der Tragwerke sowohl relevant als auch ausreichend genau sind. Die gemessenen Daten konnen explizit in probabilistische Berechnungsmodelle fur die Nachrechnung einer Brucke einfliesen. Dadurch wird das Modell sukzessive an die Realitat angenahert — in anderen Worten: zugescharft. Die Zuverlassigkeit der Ergebnisse der Nachrechnung steigt.
In diesem Beitrag wird an einem konkreten Beispiel der gegenwartige Stand von Technik und Forschung fur ausgewahlte Fragstellungen gezeigt. Im Rahmen der erstellten Abbruchstatik einer vorgespannten Brucke aus Beton wurden Ergebnisse der zerstorungsfreien Prufung verwendet, um Spanngliedlagen fur eine Beprobung zu detektieren. Daruber hinaus wurden die Messergebnisse mit wissenschaftlichen Methoden (Phasenauswertung) ausgewertet, um den Zustand der Verpressung der Spannglieder beurteilen zu konnen. Weiterhin werden die gewonnenen Messdaten der zerstorungsfreien Prufung verwendet, um den Nachweis zu erbringen, dass auf deren Grundlage eine zuverlassigere Beurteilung der Tragfahigkeit des Bauwerkes erfolgen kann. Hierfur werden die ersten Ergebnisse der Voruntersuchungen fur den Biegenachweis der vorgespannten Brucke prasentiert.
Supplementary Table S2 from Modulation of Activation-Loop Phosphorylation by JAK Inhibitors Is Binding Mode Dependent (2023)

&lt;p&gt;PDF file - 111K, Overview of phosphopeptides detected by mass-spectrometry following treatment of SET-2 cells with different JAK inhibitors. Changes in phosphopeptide abundance following JAK inhibitor treatment versus DMSO vehicle control treatment in the different experiments are displayed as log2 ratios calculated from duplicate runs. No value = not detected.&lt;/p&gt;
Pharmacological treatment and other predictors of treatment outcomes in previously untreated patients with schizophrenia: results from the European Schizophrenia Outpatient Health Outcomes (SOHO) study (2005)

The present study aimed to compare health outcomes and tolerability according to antipsychotic medication (olanzapine, risperidone or an oral typical antipsychotic) after 6 months of treatment in a group of 919 schizophrenic patients who had never previously been treated with antipsychotics. Demographic and clinical predictors of outcome were also identified. Data were extracted from the Schizophrenia Outpatient Health Outcomes (SOHO) study, a prospective, observational study of schizophrenia treatment in 10 European countries. Patients who initiated olanzapine were more likely to have a clinical response than those in the risperidone cohort, and had a greater improvement in quality of life than patients in the risperidone or typical antipsychotic cohorts. High negative and depression symptom scores at baseline and the presence of extrapyramidal symptoms at baseline predicted a worse clinical response, whereas hostile behaviour, paid employment and substance abuse predicted a better clinical outcome. The olanzapine cohort gained more weight than patients in the risperidone cohort, but no significant difference in weight gain was observed between olanzapine and the oral typical antipsychotic cohort. The results should be interpreted conservatively due to the observational study design.
Effects of Toceranib Phosphate on Systolic Blood Pressure and Proteinuria in Dogs (2016)

Toceranib phosphate treatment might result in increased systolic blood pressures in dogs. Systemic hypertension should be considered a potential adverse effect of this drug in dogs. Systemic hypertension and proteinuria were detected at clinically relevant frequencies in the dogs with cancer before antineoplastic therapies suggesting that monitoring of these variables might be warranted in this population.
Data Mining to Generate Adverse Drug Events Detection Rules (2011)

Adverse drug events (ADEs) are a public health issue. Their detection usually relies on voluntary reporting or medical chart reviews. The objective of this paper is to automatically detect cases of ADEs by data mining. 115,447 complete past hospital stays are extracted from six French, Danish, and Bulgarian hospitals using a common data model including diagnoses, drug administrations, laboratory results, and free-text records. Different kinds of outcomes are traced, and supervised rule induction methods (decision trees and association rules) are used to discover ADE detection rules, with respect to time constraints. The rules are then filtered, validated, and reorganized by a committee of experts. The rules are described in a rule repository, and several statistics are automatically computed in every medical department, such as the confidence, relative risk, and median delay of outcome appearance. 236 validated ADE-detection rules are discovered; they enable to detect 27 different kinds of outcomes. The rules use a various number of conditions related to laboratory results, diseases, drug administration, and demographics. Some rules involve innovative conditions, such as drug discontinuations.
Microwave‐Assisted Solvent‐Free Synthesis of trans‐Cinnamic Acids Using Lithium Chloride as Catalyst. (2004)

Abstract For Abstract see ChemInform Abstract in Full Text.
The synthesis of specialty narratives from co-citation clusters (1986)

A method is described for generating reviews or synopses of scientific fields called specialty narratives. The raw data for the narrative are the Science Citation Index and selected texts from the published scientific literature. The review process is modeled as a walk through a co-citation network using a quasi-minimal spanning tree path and a depth-first search method. Text for the narrative is derived from a statistical analysis of passages which cite the core (highly cited) documents in the cluster. A method is devised for selecting the passage which is most representative of the citing passages for a specific core document using shared content words. This is called the consensus passage. Transitions between nodes in the network are derived from an analysis of co-citing contexts, which reveal why the concepts represented by the documents are associated. The final specialty narrative consists of consensus passages ordered by the tree search, and connected to one another by transitional sentences. The method is applied to a co-citation cluster in the field of cancer virology, and the resulting specialty narrative is described in relation to the structure of the original co-citation map. Implications of the procedure for the cognitive processes involved in reviewing a field, and the extension of the method to other fields and higher level maps of science are discussed. © 1986 John Wiley & Sons, Inc.
Regular performance feedback may be key to maintain good quality DKA management: results from a five-year study (2019)

Based on these results, we recommend regular audit and feedback is required to sustain improvements in DKA management.
Stochastic Optimal Energy Dispatch (1981)

This paper presents a useful algorithm to incorporate the effects of uncertain system parameters into optimal power dispatch. This method employs the multivariate Gram-Charlier series as means of modeling the probability density function (p.d.f.) which characterizes the uncertain parameters. The proposed method is a direct ettelilob of existing techniques: therefore, minimal additional computation effort is necessary. Potential applications include the calculation of probabilistic parameters (eg., probability, expectation) relating to power dispatch. An example of such a parameter the probability of a bus voltage out of range during optimal dispatch. A practical example is pursued to demonstrate the usefulness of the method.
Cobalt-Catalyzed Acceptorless Alcohol Dehydrogenation: Synthesis of Imines from Alcohols and Amines (2013)

A cobalt catalyst has been developed for the acceptorless dehydrogenation of alcohols and applied to synthesize imines from alcohols and amines. Deuterium labeling studies suggest that the reaction proceeds by an initial reversible alcohol dehydrogenation step involving a cobalt hydride intermediate.
Interplay of VIP and nitric oxide in regulation of the descending relaxation phase of peristalsis (1993)

Involvement of vasoactive intestinal peptide (VIP) and nitric oxide (NO) in neurally induced relaxation was examined in smooth muscle from rat colon. Relaxation induced by field stimulation or radial stretch (i.e., descending relaxation phase of the peristaltic reflex) was accompanied by VIP release and NO production. NG-nitro-L-arginine (L-NNA) abolished NO production in both preparations but only partly inhibited VIP release (45 +/- 8% at 8 Hz and 59 +/- 10% at 10 g stretch) and relaxation (62 +/- 5% and 35 +/- 6%); the effect of L-NNA was reversed by L-arginine but not D-arginine. The pattern implied that NO production normally acts to enhance VIP release. In addition, VIP induced relaxation and stimulated NO production in muscle strips and isolated colonic muscle cells: L-NNA abolished NO production but only partly inhibited relaxation (58 +/- 6%); oxyhemoglobin had no effect. The effect of L-NNA on relaxation was reversed by L-arginine but not by D-arginine. The protein kinase A inhibitor (R)-p-adenosine 3',5'-cyclic phosphorothioate [(R)-p-cAMPS] and the protein kinase G inhibitor KT5823 inhibited VIP-induced relaxation by 76 +/- 5 and 35 +/- 4%, respectively; a combination of the two inhibitors abolished relaxation. (R)-p-cAMPS blocked the direct relaxant effect of VIP, whereas KT5823 blocked the indirect effect of VIP mediated by NO.(ABSTRACT TRUNCATED AT 250 WORDS)
Miniaturized Devices for Free Space Quantum Key Distribution; in Your Pocket and in Space (2019)

Quantum Key Distribution (QKD) is a method of generating physically secure links over a quantum channel guarateed by the laws of physics rather than mathematical complexity. There exists commercial QKD systems which are designed for integration into data centres and as such are large and expensive. We have developed a miniaturized source which is suitable for integration into novel applications.
The Theil Index in Sequences of Nested and Hierarchic Grouping Structures: Implications for the Measurement of Inequality through Time with Data Aggregated at Different Levels of Industrial Classification (2000)

This paper deepens and extends the conclusion by Conceição and Galbraith [2000] that, under some very general conditions, the dynamics of overall inequality can be captured using only the between sector component of the Theil index. This paper explores the fractal properties of the Theil index, and presents a more compelling empirical illustration. The fractal property of the Theil index results directly from its characteristic of perfect decomposability, which allows for the separation of inequality into between- and a within-groups components, provided that the groups are mutually exclusive and completely
Linear RF Polar Modulated SiGe Class E and F Power Amplifiers (2006)

Two fully-integrated linearized polar modulated class E and F power amplifiers (PA) with switch-mode supply modulation are presented. The PAs are implemented in a 0.18/spl mu/m SiGe BiCMOS process and can be used to transmit varying envelope RF signals operating at 870-920MHz. The class E PA gives a peak output power of 26.4dBm and a maximum efficiency of 62%. The class F PA gives peak output power of 23dBm with 53 % drain efficiency. When using delta modulation to control the switch-mode supply, the class F and E polar amplifiers give ACPRs for an EDGE input waveform (at 400kHz offset) of -46dBc and -37.7dBc respectively.
Optimization of neural network architecture for classification of radar jamming FM signals (2017)

The purpose of this study is to investigate several artificial Neural Network (NN) architectures in order to design a cognitive radar system capable of optimally distinguishing linear Frequency-Modulated (FM) signals from bandlimited Additive White Gaussian Noise (AWGN). The goal is to create a theoretical framework to determine an optimal NN architecture to achieve a Probability of Detection (PD) of 95% or higher and a Probability of False Alarm (PFA) of 1.5% or lower at 5 dB Signal to Noise Ratio (SNR). Literature research reveals that the frequency-domain power spectral densities characterize a signal more efficiently than its time-domain counterparts. Therefore, the input data is preprocessed by calculating the magnitude square of the Discrete Fourier Transform of the digitally sampled bandlimited AWGN and linear FM signals to populate a matrix containing N number of samples and M number of spectra. This matrix is used as input for the NN, and the spectra are divided as follows: 70% for training, 15% for validation, and 15% for testing. The study begins by experimentally deducing the optimal number of hidden neurons (1-40 neurons), then the optimal number of hidden layers (1-5 layers), and lastly, the most efficient learning algorithm. The training algorithms examined are: Resilient Backpropagation, Scaled Conjugate Gradient, Conjugate Gradient with Powell/Beale Restarts, Polak-Ribiére Conjugate Gradient, and Variable Learning Rate Backpropagation. We determine that an architecture with ten hidden neurons (or higher), one hidden layer, and a Scaled Conjugate Gradient for training algorithm encapsulates an optimal architecture for our application.
Identification of novel chondroitin proteoglycans in Caenorhabditis elegans : embryonic cell division depends on CPG-1 and CPG-2 (2006)

Vertebrates produce multiple chondroitin sulfate proteoglycans that play important roles in development and tissue mechanics. In the nematode Caenorhabditis elegans, the chondroitin chains lack sulfate but nevertheless play essential roles in embryonic development and vulval morphogenesis. However, assignment of these functions to specific proteoglycans has been limited by the lack of identified core proteins. We used a combination of biochemical purification, Western blotting, and mass spectrometry to identify nine C. elegans chondroitin proteoglycan core proteins, none of which have homologues in vertebrates or other invertebrates such as Drosophila melanogaster or Hydra vulgaris. CPG-1/CEJ-1 and CPG-2 are expressed during embryonic development and bind chitin, suggesting a structural role in the egg. RNA interference (RNAi) depletion of individual CPGs had no effect on embryonic viability, but simultaneous depletion of CPG-1/CEJ-1 and CPG-2 resulted in multinucleated single-cell embryos. This embryonic lethality phenocopies RNAi depletion of the SQV-5 chondroitin synthase, suggesting that chondroitin chains on these two proteoglycans are required for cytokinesis.
ChemInform Abstract: Chemo‐ and Regioselective Conversion of Epoxides to Carbonyl Compounds in 5 M Lithium Perchlorate‐Diethyl Ether Medium. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
The secondary resistome of multidrug-resistant Klebsiella pneumoniae (2017)

Klebsiella pneumoniae causes severe lung and bloodstream infections that are difficult to treat due to multidrug resistance. We hypothesized that antimicrobial resistance can be reversed by targeting chromosomal non-essential genes that are not responsible for acquired resistance but essential for resistant bacteria under therapeutic concentrations of antimicrobials. Conditional essentiality of individual genes to antimicrobial resistance was evaluated in an epidemic multidrug-resistant clone of K. pneumoniae (ST258). We constructed a high-density transposon mutant library of >430,000 unique Tn5 insertions and measured mutant depletion upon exposure to three clinically relevant antimicrobials (colistin, imipenem or ciprofloxacin) by Transposon Directed Insertion-site Sequencing (TraDIS). Using this high-throughput approach, we defined three sets of chromosomal non-essential genes essential for growth during exposure to colistin (n = 35), imipenem (n = 1) or ciprofloxacin (n = 1) in addition to known resistance determinants, collectively termed the "secondary resistome". As proof of principle, we demonstrated that inactivation of a non-essential gene not previously found linked to colistin resistance (dedA) restored colistin susceptibility by reducing the minimum inhibitory concentration from 8 to 0.5 μg/ml, 4-fold below the susceptibility breakpoint (S ≤ 2 μg/ml). This finding suggests that the secondary resistome is a potential target for developing antimicrobial "helper" drugs that restore the efficacy of existing antimicrobials.
Critical control of competition between metallic ferromagnetism and charge/orbital correlation in single crystals of perovskite manganites (2003)

The transition between a ferromagnetic metal and an insulator with short-range charge/orbital correlation has been investigated for the manganites ${R}_{0.55}{\mathrm{Sr}}_{0.45}{\mathrm{MnO}}_{3}$ $[R=\mathrm{Sm},$ Eu, Gd, and ${\mathrm{Sm}}_{1\ensuremath{-}y}{\mathrm{Gd}}_{y}$ $(0&lt;~y&lt;~1)]$. The phase diagram as a function of the averaged radius of perovskite A-site cations is entirely modified from the prototypical bicritical phase diagram, e.g., for ${\mathrm{Pr}}_{0.55}({\mathrm{Ca}}_{1\ensuremath{-}y}{\mathrm{Sr}}_{y}{)}_{0.45}{\mathrm{MnO}}_{3}$ with the competition between the ferromagnetic metal and charge/orbital-ordered insulator. Larger randomness via the local lattice distortion in ${R}_{0.55}{\mathrm{Sr}}_{0.45}{\mathrm{MnO}}_{3}$ enhances the phase fluctuation between ferromagnetic metal and charge/orbital-ordered insulator and suppresses their long-range orders.
Leptin Promotes the Development of Mouse Preimplantation Embryos in Vitro (2002)

Leptin acts as a modulator of diverse reproductive functions, and recent studies have implicated involvement of leptin in the early embryo development in mammal. The aim of this study was to investigate the expression of leptin and its receptor (OB-R) in mouse oocyte and preimplantation embryo, and to examine whether leptin influenced the early embryo development. Leptin mRNA was detected in blastocyst and hatched blastocyst, and two splice variants of OB-R (OB-Ra and OB-Rb) mRNAs were detected in oocytes, 1-cell, 2-cell, morula, blastocyst, and hatched blastocyst. As for the origin of leptin, both leptin mRNA and protein were identified in the oviduct epithelium and endometrium of pregnant mouse. In the pregnant mouse, the levels of leptin in uterine fluid were higher than those in nonpregnant mouse. Addition of leptin to embryo culture media promotes the development from 2-cell stage embryos to the blastocysts, fully expanded blastocysts and hatched blastocysts. This effect was neutralized by an antibody against the extracellular domain of OB-R. Leptin significantly increased the total cell number of blastocysts, and the effect was preferentially observed in the trophectoderm. These findings raise the possibility of a paracrine/autocrine leptin signaling system regulating the development of mouse preimplantation embryo.
Electrolytic systems and methods for making metal halides and refining metals (2023)

Disclosed are electrochemical cells and methods for producing a halide of a non-alkali metal and for electrorefining the halide. The systems typically involve an electrochemical cell having a cathode structure configured for dissolving a hydrogen halide that forms the halide into a molten salt of the halogen and an alkali metal. Typically a direct current voltage is applied across the cathode and an anode that is fabricated with the non-alkali metal such that the halide of the non-alkali metal is formed adjacent the anode. Electrorefining cells and methods involve applying a direct current voltage across the anode where the halide of the non-alkali metal is formed and the cathode where the non-alkali metal is electro-deposited. In a representative embodiment the halogen is chlorine, the alkali metal is lithium and the non-alkali metal is uranium.
Electric field effect on the phase diagram of a bent-core liquid crystal (2013)

We have investigated the effects of a low frequency electric field on the thermotropic behavior of a nematogenic bent-core liquid crystal by means of X-ray diffraction. We have determined for the first time the 2D phase diagram of the bent-core mesogen over an extended temperature-field (T, E) space. The results show that the electric field strongly affects both the mesophase sequence and the transition temperatures of the sample. An extraordinary field-induced shift of the nematic–isotropic phase transition is found, which has neither any experimental counterpart in conventional calamitic LCs, nor can be explained by the presently available theories. The phase diagram points out the existence of exotic phase transitions driven by either electric field or temperature along specific paths in the (T, E) space. In particular, the isothermal field-induced transition from the NCybC to the NCybA phase represents a breakthrough in the interpretation of previous XRD experimental results. These experimental findings provide further strong support of the now widely accepted cybotactic cluster picture of the nematic phase of bent-core mesogens.
Expressing Certainty of a Mobile Robot with Artificial Subtle Expressions (2013)

In this paper, h-ASE(hesitation-based Artificial Subtle Expression) as a novel implementation of ASE is described, in which a robot expresses confidence in its advice to a human. Confidence in advice is one of robot's useful internal states, and it is an important goal to develop a practical and inexpensive methodology to correctly express it. To achieve this goal, we propose h-ASE in which a robot slowly hesitates by turning to a human before giving advice with low confidence. We conducted experiments to verify the effectiveness of h-ASE and investigate the influences of two independent variables, time-delay and slow-motion, with participants. As a result, we obtained promising results which shows the time-delay factor significantly contributed to h-ASE than the slow-motion factor.
Jumping Gall Wasp, California Jumping Gall Wasp, Jumping Oak Gall, Flea Seeds Neuroterus saltatorius Edwards (Insecta: Hymenoptera: Cynipidae) (2017)

Includes: Introduction - Synonymy - Distribution - Description - Life Cycle - Hosts - Ecology - Damage - Management - Selected References&#x0D; Also available on the Featured Creatures website at http://entnemdept.ufl.edu/creatures/trees/Neuroterus_saltatorius.htm