gebhart/patrepeval huggingface dataset:
The trephiners of Blanche Bay, New Britain, their instruments and methods (1938)

Journal Article The trephiners of Blanche Bay, New Britain, their instruments and methods Get access Isadore Brodsky Isadore Brodsky Department of Surgery, University of Sydney Search for other works by this author on: Oxford Academic Google Scholar British Journal of Surgery, Volume 26, Issue 101, July 1938, Pages 1–9, https://doi.org/10.1002/bjs.18002610102 Published: 05 December 2005
Clot Retention - A Simple New Method of Evacuation with Out Toomey's or Ellick's: A Clinical (2015)

Background: The purpose of this clinical study was to assess whether our new method of clot evacuation is useful and better compared to conventional methods clot retention in the urinary bladder is a most common problem in surgical and non-surgical cases. Based our experience of 122 cases managed in 26 years. We discuss some guide lines which make this a safer and easier to perform. Materials and Methods: During the period of June 1990 to June 2015, 122 cases of clot retention were treated. The nonsurgical causes are upper tract bleeding, drug-induced bleeding, post-traumatic bleeding, and hemato-chyluria. The Surgical causes are the most common is post transurethral resection of the prostate bleeding. Results: On reviewing the cases 115 males and 7 cases for females, it was found this method very simply and does not require any evacuator or syringe. This method easily adoptable and acceptable and no training are required. Conclusion: Clot retention in the urinary bladder is the most common problem in surgical and non-surgical cases. Our technique of simple Venky’s Suction and Nelton’s catheter will help without any extra expenditure.
Localization of substance P-like immunoreactivity within the monkey retina. (1982)

Substance P (SP)--like immunoreactivity has been localized to distinct retinal cell populations in the primate Macaca nemestrina by means of immunohistochemical techniques with a well-characterized monoclonal antiserum directed to SP. The specificity of the immunoreactive staining was established by absorption of the antiserum with 10 micro M synthetic SP. Specific SP-like immunoreactivity was observed within varicose processes located in the outer plexiform layer, inner nuclear layer (INL), and in three bands within the inner plexiform layer (IPL). SP-immunoreactive somata were located in the proximal INL, IPL, and ganglion cell layer. These studies have thus identified SP-containing amacrine cells, interstitial amacrine cells, and displayed amacrine cells. In addition, these studies suggest the existence of SP-containing interplexiform cells and perhaps ganglion cells.
A Convenient Route to Aryl Trifluoromethyl Sulfones by Fluoride-Catalyzed Cross-Coupling of Arenesulfonyl Fluorides with (Trifluoromethyl)trimethylsilane and (Trifluoromethyl)trimethylstannane (1990)

Trifluoromethylsulfonyl substituted aromatic compounds 3a-d are prepared from the corresponding sulfonyl fluorides 1a-d by reacting with (trifluoromethyl)trimethylsilane (or-stannane) in the presence of a base under mild conditions in high yields.
An Integrated Approach To Music Boundary Detection. (2009)

[TODO] Add abstract here.
Axis-dependent carrier polarity in polycrystalline NaSn2As2 (2021)

Transverse thermoelectric devices consist of only one thermoelectric material, unlike conventional longitudinal thermoelectric devices that require two types of thermoelectric materials with p- and n-type polarities. However, scalable synthesis of materials that demonstrate axis-dependent carrier polarity, which is a prospective component to demonstrate the transverse thermoelectric device, is challenging. This paper reports that polycrystalline NaSn2As2, which was prepared by using uniaxial hot pressing, displayed axis-dependent carrier polarity. The preferred orientation of the sample was confirmed through x-ray diffraction measurements. Seebeck coefficient measurements indicate that carrier polarity depends on the measurement direction, which is consistent with recently reported results on single crystals of NaSn2As2. Given that our sample preparation procedure is readily scalable, the present work shows the possibility for preparing transverse thermoelectric devices using polycrystalline NaSn2As2 with a preferred orientation.
Guidelines for Developing Amide-Based Hydrogen Storage Materials (2005)

An effective method for developing amide-based high-performance hydrogen storage materials is to prepare appropriate combinations of amides and hydrides. We have proposed that a mixture of an amide with a low decomposition temperature and a hydride showing rapid reaction to ammonia would be an appropriate combination. According to this proposal, the mixture of Mg(NH2)2 (Mg amide) and LiH (Li hydride) was investigated. The dehydriding temperature of the mixture of Mg(NH2)2 and 4·LiH is lower than that of the mixture of LiNH2 (Li amide) and 2·LiH. A method for preventing ammonia release is increasing the LiH ratio in the mixtures, which results in a reduction in the amount of desorbed hydrogen. The homogeneous dispersion between Mg(NH2)2 and LiH might be also an important factor for preventing ammonia release.
Star-shaped D–π–A oligothiophenes with a tris(2-methoxyphenyl)amine core and alkyldicyanovinyl groups: synthesis and physical and photovoltaic properties (2016)

We report a series of D–π–A star-shaped oligomers with a tris(2-methoxyphenyl)amine core and alkyldicyanovinyl groups.
The Expression Patterns and Clinical Significance of microRNAs in Liver Diseases and Hepatocellular Carcinoma (2012)

MicroRNAs (miRNAs) are approximately 22-nucleotide noncoding RNAs that constitute silencers of target gene expression and have emerged as key regulatory molecules of mammalian cell functions. Aberrant miRNA expression promotes pathologic conditions including hepatocellular carcinoma (HCC) and a variety of precancerous liver diseases, especially chronic hepatitis B and C, and liver cirrhosis. miRNAs may contribute to HCC development by acting as oncogenes or tumor suppressors. Specific alterations of miRNA expression have also been related to clinical features of HCC, such as stage, differentiation, prognosis, and response to adjuvant therapy. miRNA signatures may help define molecular profiles of liver diseases as biomarkers, and allow classification of different stages of cirrhosis and HCC progression. Either miRNAs, or anti-miRNA oligonucleotides (antagomirs) could be used for in vivo modulation of miRNA actions, and thus have significant potential in molecularly targeted therapy.
Design and fabrication of large fiber-mode-matched three-dimensional adiabatic tapered couplers for integrated optics (2010)

We presented the design and fabrication of fiber-mode-matched three-dimension (3D) tapered couplers for efficient coupling light from fibers to photonic integrated circuits (PICs). The 3D adiabatic taper was made by SU8 and the structure was designed by beam propagation method (BPM). Measuring waveguide transmission with this 3D taper, we observed that the coupling efficiency was improved by 12 dB. The misalignment tolerance can be around 5 μm.
Software-directed power-aware interconnection networks (2005)

Interconnection networks have been deployed as the communication fabric in a wide range of parallel computer systems. With recent technological trends allowing growing quantities of chip resources and faster clock rates, there have been prevailing concerns of increasing power consumption being a major limiting factor in the design of parallel computer systems, from multiprocessor SoCs to multi-chip embedded systems and parallel servers. To tackle this, power-aware networks must become inherent components of single-chip and multi-chip system.On the hardware design side, while there has been some recent interconnection network power reduction research, especially targeted towards communication links, the techniques presented are ad hoc and are not tailored to the application running on the network. We show that with these ad hoc techniques, power savings and corresponding impact on network latency vary significantly from one application to the next -- in many cases network performance can suffer severely. On the software side, extensive research on compile-time optimization has produced parallelizing compilers that can efficiently map an application onto hardware for high performance. However, research into power-aware parallelizing compilers is in its infancy; none addressed communication power.In this paper, we take the first steps towards tailoring applications' communication needs at run-time for low power. We propose software techniques that extend the flow of a parallelizing compiler in order to direct run-time network power optimization. We target network links, the dominant power consumer in these systems, allowing DVS instructions extracted during static compilation to orchestrate link voltage and frequency transitions for power savings during application runtime. Concurrently, a hardware online mechanism measures network congestion levels and adapts these off-line DVS settings to optimize network performance. Our simulations show that link power consumption can be greatly reduced by up to 76.3%, with a minor increase in network latency in the range of 0.23 to 6.78% across a number of benchmark suites running on three existing parallel architectures, from very fine-grained single-chip to coarse-grained multi-chip architectures.
V−V Energy Transfer from Highly Vibrationally Excited Molecules through Transition Dipole Coupling:  A Quantitative Test on Energy Transfer from SO2 (v ≫ 0) to SF6(31) (2000)

Time-resolved Fourier transform IR emission spectroscopy has been used to monitor the population distribution of both the energy giving molecules and the energy receiving molecules during collisional quenching of highly vibrationally excited SO2 by bath-gas SF6. The change in population of the SF6 v3 = 1 level measured as a function of time is compared with that calculated based on the transition dipole coupling model with the transition dipole of highly excited SO2 extracted from its IR emission spectra. The excellent agreement indicates that long-range interaction through transition dipole coupling is responsible for the vibration to vibration energy transfer from the highly excited molecules.
Ondansetron use is associated with lower COVID-19 mortality in a Real-World Data network-based analysis (2021)

ABSTRACT Objective The COVID-19 pandemic generated a massive amount of clinical data, which potentially holds yet undiscovered answers related to COVID-19 morbidity, mortality, long term effects, and therapeutic solutions. The objective of this study was to generate insights on COVID-19 mortality-associated factors and identify potential new therapeutic options for COVID-19 patients by employing artificial intelligence analytics on real-world data. Methods A Bayesian statistics-based artificial intelligence data analytics tool (bAIcis®) within Interrogative Biology® platform was used for network learning, inference causality and hypothesis generation to analyze 16,277 PCR positive patients from a database of 279,281 inpatients and outpatients tested for SARS-CoV-2 infection by antigen, antibody, or PCR methods during the first pandemic year in Central Florida. This approach generated causal networks that enabled unbiased identification of significant predictors of mortality for specific COVID-19 patient populations. These findings were validated by logistic regression, regression by least absolute shrinkage and selection operator, and bootstrapping. Results We found that in the SARS-CoV-2 PCR positive patient cohort, early use of the antiemetic agent ondansetron was associated with increased survival in mechanically ventilated patients. Conclusions The results demonstrate how real world COVID-19 focused data analysis using artificial intelligence can generate valid insights that could possibly support clinical decision-making and minimize the future loss of lives and resources.
Cloning and analysis of the rat gamma-glutamyltransferase gene. (1990)

We have isolated and characterized a complete structural gene encoding the enzyme gamma-glutamyltransferase ((5-glutamyl)-peptide:amino acid 5-glutamyltransferase; EC 2.3.2.2). The gene contains 8 exons and spans approximately 12 kilobases. Ras-transformed rat liver epithelial cells and rat kidney express RNAs which differ in length by approximately 0.3 kilobase pair. Comparison of the genomic sequence with kidney gamma GT cDNA sequence indicates that the first exon is noncoding, and nuclease protection and primer extension data have identified a potential kidney transcription start site (defined as +1) for this exon. The site is not associated with a TATA box, but there are two CCAAT boxes (-136 and -599) and two sites (-101 and -746) containing the consensus sequences to which the transcription factor SP1 is known to bind. There is also a sequence at -453 (TGTGGTTG) that is highly homologous to the core sequence (TGTGG(T)3-5G) of SV40 and polyoma viral enhancers.
Biophysical Characterization of Peptides and Their Interaction with Lysenin Nanopores (2017)

Translocation of single molecules through biological nanopores provides valuable information about the physical and chemical structure of analytes. Such nanopores have been envisioned as tools for sequencing, biosensing, or characterization of biological interactions. However, many biological nanopores have limitations in regard to undesirable interactions with analytes, difficult insertion, and low transport potential. To overcome these issues, we examined lysenin, a pore-forming protein from the earthworm E. foetida, which self-inserts 3 nm diameter pores into lipid membranes containing sphingomyelin. In this work, we investigated translocation of peptides through lysenin channels. The first peptide we studied, WWHPC, can manifest as a monomer or dimer. Our other peptide, HMWWM, occurs only as a monomer. By using the resistive pulse technique, lysenin is able to distinguish between these two forms. In conclusion, these results show that lysenin can be used as a single molecule biosensor and for single molecule characterization.
Kinematics and timing of Tertiary extension in the western Lake Mead region, Nevada: Reply (1995)

Research Article| August 01, 1995 Kinematics and timing of Tertiary extension in the western Lake Mead region, Nevada: Reply Ernest M. Duebendorfer; Ernest M. Duebendorfer 1Department of Geology, P.O. Box 4099, Northern Arizona University, Flagstaff, Arizona 86011 Search for other works by this author on: GSW Google Scholar David A. Simpson David A. Simpson 2Department of Geoscience, University of Nevada, Las Vegas, Nevada 89154 Search for other works by this author on: GSW Google Scholar Author and Article Information Ernest M. Duebendorfer 1Department of Geology, P.O. Box 4099, Northern Arizona University, Flagstaff, Arizona 86011 David A. Simpson 2Department of Geoscience, University of Nevada, Las Vegas, Nevada 89154 Publisher: Geological Society of America First Online: 20 Feb 2019 Online Issn: 1943-2674 Print Issn: 0016-7606 Geological Society of America GSA Bulletin (1995) 107 (8): 990–994. https://doi.org/10.1130/GSAB-v107-p990 Article history First Online: 20 Feb 2019 Cite View This Citation Add to Citation Manager Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Get Permissions Search Site Citation Ernest M. Duebendorfer, David A. Simpson; Kinematics and timing of Tertiary extension in the western Lake Mead region, Nevada: Reply. GSA Bulletin 1995;; 107 (8): 990–994. doi: https://doi.org/10.1130/GSAB-v107-p990 Download citation file: Ris (Zotero) Refmanager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentBy SocietyGSA Bulletin Search Advanced Search Abstract Çakir and Aydin raise three general points in the opening paragraph of their Discussion to which we would like to respond directly. First, Çakir and Aydin state that we overlooked age relations among various structures in the region and that we misrepresented their model. Second, Çakir and Aydin challenge the applicability of the kinematic analysis technique of Marrett and Allmendinger (1990) that we employed in our study. Finally, Çakir and Aydin claim that we propose a model that is inconsistent with our own arguments. Following a brief discussion of these main points, we key our response to each individual point that they raise in their Discussion. This content is PDF only. Please click on the PDF icon to access. First Page Preview Close Modal You do not have access to this content, please speak to your institutional administrator if you feel you should have access.
Shape evolution of perovskite LaFeO3 nanostructures: a systematic investigation of growth mechanism, properties and morphology dependent photocatalytic activities (2013)

Shape evolution of nanostructured LaFeO3 with fascinating morphologies like cubes, rods and spheres was successfully synthesized by a facile and environmentally friendly hydrothermal process. Tuning the morphologies was achieved using different surfactants. The prepared samples were systematically characterized using X-ray diffraction, micro-Raman spectroscopy, scanning electron microscopy and high-resolution transmission electron microscopy for structural, morphological and chemical composition analysis by X-ray photoelectron spectroscopy. The optical properties of prepared samples were studied employing UV-Vis diffusion reflectance analysis. Brunauer–Emmett–Teller measurement reveals a large surface area for all the prepared nanostructures. Most importantly, the visible-light photocatalytic activities of the three LaFeO3 nanostructures were evaluated by photocatalytic decolorization of Rhodamine B in aqueous solution. The enhanced photocatalytic activity of LaFeO3 nanospheres compared to other nanostructures and commercial Degussa P25 TiO2 can be ascribed to high specific surface area, pore size distribution and the smaller particle size. The underlying growth mechanism responsible for the formation of LaFeO3 nanostructures is also discussed. The results from this study illustrate the morphology-dependent photocatalytic performance of LaFeO3.
On the Frequency Dispersion in DBF SAR and Digital Scalloped Beamforming (2020)

Digital beamforming (DBF) with Scan-On-Receive (SCORE) in elevation is a powerful technique for spaceborne synthetic aperture radar (SAR) to achieve high-resolution wide-swath (HRWS) images. DBF in spaceborne SAR should be implemented in real-time to reduce the volume of the downloaded data. Current digital beamformers in SAR systems usually use phase shift instead of a time delay network to ensure real-time implementation. However, conventional phase shift DBF SAR with narrow array bandwidth is not applicable for broadband signals. The beam steering deviation as a function of frequency is obvious for signals with large fractional bandwidth, which appears as a phenomenon of frequency dispersion. If the signal bandwidth is wider than the array bandwidth, frequency dispersion can significantly deteriorate the signal-to-noise ratio (SNR) and must be well relieved. This article analyzes the frequency dispersion in DBF SAR and proposes an innovative DBF-SCORE scheme with specially designed scalloped beam. The proposed digital scalloped beamforming (DSBF) scheme is effective in relieving the influence of frequency dispersion in DBF SAR. Theoretical analysis and simulation results validate the effectiveness of the proposed scheme. The proposed DSBF scheme gives practical solution to the problem of frequency dispersion in broadband DBF SAR, which makes DBF-SCORE a more practical technique for future spaceborne HRWS SAR.
A Preclinical Evaluation towards the Clinical Application of Oxygen Consumption Measurement by CERMs by a Mouse Chimera Model (2019)

We have developed an automated device for the measurement of oxygen consumption rate (OCR) called Chip-sensing Embryo Respiratory Measurement system (CERMs). To verify the safety and the significance of the OCR measurement by CERMs, we conducted comprehensive tests using a mouse model prior to clinical trials in a human in vitro fertilization (IVF) program. Embryo transfer revealed that the OCR measured by CERMs did not compromise the full-term development of mice or their future fertility, and was positively correlated with adenosine triphosphate (ATP) production and the mitochondrial membrane potential (ΔΨm), thereby indirectly reflecting mitochondrial oxidative phosphorylation (OXPHOS) activity. We demonstrated that the OCR is independent of embryo morphology (the size) and number of mitochondria (mitochondrial DNA copy number). The OCR correlated with the total cell numbers, whereas the inner cell mass (ICM) cell numbers and the fetal developmental rate were not. Thus, the OCR may serve as an indicator of the numbers of trophectoderm (TE) cells, rather than number or quality of ICM cells. However, implantation ability was neither correlated with the OCR, nor the embryo size in this model. This can probably be attributed to the limitation that chimeric embryos contain non-physiological high TE cells counts that are beneficial for implantation. CERMs can be safely employed in clinical IVF owing to it being a safe, highly effective, non-invasive, accurate, and quantitative tool for OCR measurement. Utilization of CERMs for clinical testing of human embryos would provide further insights into the nature of oxidative metabolism and embryonic viability.
Automatic prosody generation using suprasegmental unit selection (1998)

Text-to-Prosody systems based on the use of prosodic databases extracted from natural speech will be a key point for further development of new Text-to-Speech systems. This paper
AKR1C3 Expression in T and B Acute Lymphoblastic Leukemia/Lymphoma for Clinical Use as a Biomarker (2021)

Abstract Objectives: To investigate aldo–keto reductase 1C3 (AKR1C3) expression in T and B acute lymphoblastic leukemia/lymphoma (ALL) patients. Methods: Three commercial antibodies were evaluated for AKR1C3 immunohistochemistry (IHC) staining performance: Polyclonal Thermofisher scientific (Clone#PA523667), rabbit monoclonal Abcam [EPR16726] (ab209899) and Sigma/Millipore anti-AKR1C3 antibody, mouse monoclonal, clone NP6.G6.A6, purified from hybridoma cell culture. Initial optimization was performed on cell line controls: HCT116 (negative control); genetically modified cell line HCT116 with AKR1C3 overexpression; Nalm and TF1 cell lines. Twenty normal bone marrows from archival B and T-ALL patient samples were subsequently examined. AKR1C3 expression levels in these samples were evaluated by immunohistochemistry, Protein Wes and quantitative RT-PCR. Results: Sigma/Millipore Anti-AKR1C3 antibody (mouse monoclonal, clone NP6.G6.A6) showed higher specificity compared to rabbit polyclonal antibody by immunohistochemistry. H-score was used to quantify percent of nuclear immunoreactivity for AKR1C3 with varying disease involvement. T-ALL samples had a higher H-score (172-190) compared to B-ALL cases (H-score, 30-160). The AKR1C3 expression in peripheral blood by Protein Wes and RT-qPCR showed concordance in relapsed/refractory and/or minimal residual T-ALL cases. Conclusions: Sigma/Millipore Anti-AKR1C3 antibody and mouse monoclonal, clone NP6.G6.A6 can be used to aid in AKR1C expression of T-ALL and in cases of relapsed/refractory and/or minimal residual disease.