gebhart/patrepeval huggingface dataset:
Reaction of tertiary aliphatic amines with 2,4-dinitrobenzenesulfenyl chloride (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReaction of tertiary aliphatic amines with 2,4-dinitrobenzenesulfenyl chlorideVincent J. Traynelis and James N. RieckCite this: J. Org. Chem. 1973, 38, 25, 4339–4341Publication Date (Print):December 1, 1973Publication History Published online1 May 2002Published inissue 1 December 1973https://pubs.acs.org/doi/10.1021/jo00964a028https://doi.org/10.1021/jo00964a028research-articleACS PublicationsRequest reuse permissionsArticle Views37Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Kinetic Effects of Terbium Ions on Muscarinic Acetylcholine Receptors of Murine Neuroblastoma Cells (1984)

Preincubation of murine neuroblastoma cells (clone N1E-115) with terbium chloride resulted in a significant potentiation of carbachol-mediated increase in cyclic GMP formation. This effect was accompanied by a shift of the peak response from 30 s to 120 s and a 6-fold decrease in carbachol concentration producing half-maximal responses, in addition to a significant increase in the Hill coefficient. Terbium ions also caused a significant decrease in the affinity and an increase in the maximum binding of [3H]quinuclidinyl benzilate to muscarinic receptors, the change in affinity being mainly due to a decrease in the association rate. Preincubation of cells with 1 mM carbachol for 4 h (the desensitized state of the muscarinic receptor) resulted in a decrease in the ability of terbium to alter [3H]quinuclidinyl benzilate binding. The effects of terbium reported here might be due to its affecting muscarinic receptor-effector coupling, which is considered to be lost upon receptor desensitization.
Detection and quantitation of thymidylate synthase mRNA in human colon adenocarcinoma cell line resistant to 5-fluorouracil by competitive PCR. (1998)

This PCR technique is applicable for detecting TS mRNA, and the TS mRNA level was found to be increased 1.5-fold (as detected by northern blot analysis) and 4-fold (measured by competitive PCR), leading to enhanced TS catalytic activity in C1/FU in contrast to its parent cell line, C1; thus accounting for one possible resistant mechanism to FU.
Beam Diagnostics Report for the Thermal Test Conducted on 3/9/2016 (2016)

The thermal test OTR data revealed several issues with the beam focus and the target window itself. The oxidation of the target window and the prominence of a scratch across the center of the window makes it impossible to accurately measure the beam profile and size.
A Corpus-based Study on use of Copular Verbs by Chinese School Children Learning English in China (2011)

i-manager's Journal on Future Engineering and Technology, i-manager's Journal on Software Engineering, i-manager's Journal on Electrical Engineering, i-manager's Journal on Electronics Engineering, i-manager's Journal of Educational Technology, i-manager's Journal on Educational Psychology, i-manager's Journal on School Educational Technology, i-manager's Journal on English Language Teaching, i-manager's Journal on Mechanical Engineering, i-manager's Journal on Civil Engineering, i-manager's Journal on Embedded Systems, i-manager's Journal on Information Technology, i-manager's Journal on Structural Engineering, i-manager's Journal on Communication Engineering and Systems, i-manager's Journal on Wireless Communication Networks, i-manager's Journal on Instrumentation and Control Engineering, i-manager's Journal on Circuits and Systems, i-manager's Journal on Digital Signal Processing, i-manager's Journal on Power Systems Engineering, i-manager's Journal on Computer Science, i-manager's Journal on Material Science, i-manager's Journal on Cloud Computing, i-manager's Journal on Image Processing, i-manager's Journal on Mobile Applications and Technologies, i-manager's Journal on Pattern Recognition, i-manager's Journal on Mathematics, i-manager's Journal on Management, i-manager's Journal on Nursing, i-manager's Journal on Physical Sciences, i-manager's Journal on Chemical Sciences, i-manager's Journal on Economics & Commerce , i-manager's Journal on Humanities & Social Sciences, i-manager's Journal on Life Sciences , i-manager's Journal on Construction Management, i-manager's Oyla , ,India best Journal Publication Website,World Best Plication SIte,Free atrticle published website,Journal Publised,Published Journal,Research Paper Published,indian research paper publications,how to published your article/research paper in india for free,journal’s instructions for authors
Entity resolution (2012)

This tutorial brings together perspectives on ER from a variety of fields, including databases, machine learning, natural language processing and information retrieval, to provide, in one setting, a survey of a large body of work. We discuss both the practical aspects and theoretical underpinnings of ER. We describe existing solutions, current challenges, and open research problems.
Oxidative Coupling Reactions Mediated by MoCl5 Leading to 2,2′‐Cyclolignans: The Specific Role of HCl. (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
Hysteretic behavior of a belt tensioner: modelling and experimental investigation (2005)

International audience
Study of Co(or Ni)-Mo Oxide Phase Transformation and Hydrodesulfurization Catalysts by Raman Microprobe Equipped with New Cells (1982)

Heating cells used in optical microscopy are adapted to a laser Raman microprobe to an under air study of the solid phase transformation of cobalt and nickel molybdates in which the molybdenum atoms are in tetrahedral oxygen environment ([a] phase) or in octahedral environment ([b] phase). In each case, the Co or Ni environment is octahedral. In the second part of this paper, a newly designed controlled-atmosphere and temperature cell is described. It permits the study of several problems particularly those related to the reactivity of Co or Ni-Mo-γ-Al 2 O 3 hydrodesulfurization catalysts. Results on (1) sulfidation of the oxide precursor form catalysts by a H 2 -H 2 S mixture, (2) interaction with a model sulfided molecule: thiophene, and (3) pyridine chemisorption are reported.
Versuche mit der abortauslösenden Lipopolysaccharid‐Fraktion aus Brucella abortus (1961)

Zusammenfassung Am isolierten Meerschweinchenuterus wurde mit Hilfe von Oxytocin die uteruskontrahierende Wirksamkeit eines Lipopolysaccharids (Endotoxin) aus Brucella abortus beobachtet. Dieses Lipopolysaccharid bewirkt beim tragenden Meerschweinchen und Kaninchen Verwerfen, jedoch besteht eine individuell unterschiedliche Empfindlichkeit. Auf die mögliche Bedeutung des hormonalen Status der Tiere wird hingewiesen. Diese Ergebnisse führen zur Postulierung einer neuen Theorie, die den Abortvorgang bei der Bang'schen Krankheit näher erklären kann. Summary Studies on lipopolysaccharide fractions of Brucella abortus which produce abortion With the help of oxytocin the effect on uterine contraction of a lipopolysaccharide (endotoxin) from Brucella abortus was studied on the isolated guinea pig uterus. This lipopolysaccharide produces abortion in pregnant guinea pigs and rabbits but with differing susceptibility of individual animals. The possible importance of the hormonal status of the animals is mentioned. These findings suggest a new hypothesis which comes nearer to explaining abortion in Bang's Disease. Résumé Expëriences sur la fraction abortive (lipo‐polysaccharide) extraite de B. abortus Sur l'utérus de cobaye isolé on observa à l'aide d'oxytocine l'action contractive d'un lipo‐polysaccharide (endotoxine) extrait de Brucella abortus. Ce lipo‐polysaccharide provoque chez le cobaye gravide ou le lapin des avortements, mais il existe des différences de sensibilité individuelles. L'auteur signale l'importance possible de l'état hormonal des animaux. Ces résultats incitent à formuler une nouvelle théorie susceptible d'expliquer l'avortement dans la maladie de Bang. Resumen Ensayos con la fracción lipopolisacárida abortógena de Brucella abortus En el útero aislado de cobaya se observó con ayuda de oxitocina la actividad úterocontractora de un lipopolisacárido (endotoxina) de Brucella abortus. Este lipopolisacárido produce aborto en el cobaya hembra o coneja gestantes, aunque existe una sensibilidad individualmente diferente. Se hace referencia a la posible importancia del estado hormónico de los animales. Estos resultados conducen a la postulación de una nueva teoría, que puede explicar en detalle el proceso abortivo en la enfermedad de Bang.
Guided wave mode conversion phenomenon in composite materials: numerical and experimental study (2019)

In this paper results of numerical and experimental analysis of S0/A0 elastic wave mode conversion phenomenon at various discontinuities in glass fibre reinforced polymer (GFRP) panels are presented. Analysis of S0/A0 mode conversion effect at Teflon inserts simulating delamination and impact damage with energies 5 J, 10 J and 15 J is conducted. In the case of Teflon inserts circular inserts with the same diameters located at different depth and inserts with various shapes located at the same depth were investigated. Numerical analysis is based on the time domain spectral element method (SEM). SEM computational algorithm is adapted for parallel calculation using graphic processor units (GPUs). Numerical model takes also into account the influence of material damping. Numerical results are compared with experimental results based on full wavefield measurements using scanning laser Doppler vibrometry (SLDV). It is shown that based on the effects of S0/A0 mode conversion it is possible to detect the damage and determine its shape and size. In the research, auxiliary Non-Destructive Testing (NDT) method is also utilised. The aim of its application is to indicate the depth of discontinuity and to prove that delamination was created in the case of impact damage. The auxiliary method is based on terahertz spectroscopy (THz) where the analysis of propagation of electromagnetic waves in the terahertz band is conducted. The THz spectroscopy is a useful technique for damage assessment in the dielectric materials.
Uses of the nonlinear optical loop mirror (1992)

The nonlinear optical loop mirror is a fiber-based Sagnac interferometer. The device can be made from standard communications fiber and couplers and is extremely stable. The most useful version, for all-optical switching, is the two- wavelength loop mirror as illustrated in Fig. 1. The loop coupler is a 50:50 splitter and can be made to be broadband. The two couplers inside the loop couple the optical switch in and out of the loop. This arrangement achieves two functions; it effectively separates the optical circuits of the switch and signal beams and it makes the switch power available for re-use.
The metabolism of inositol 1,3,4-trisphosphate to inositol 1,3-bisphosphate. (1987)

We previously demonstrated a pathway for the metabolism of inositol 1,3,4-trisphosphate (Ins(1,3,4)P3) to inositol 3,4-bisphosphate (Ins(3,4)P2) in calf brain extracts. Inositol polyphosphate 1-phosphatase, a Mg2+-dependent, lithium ion-inhibited enzyme, specifically hydrolyzes Ins(1,3,4)P3 to Ins(3,4)P2 and Ins(1,4)P2 to Ins 4-P (Inhorn, R. C., Bansal, V. S., and Majerus, P. W. (1987) Proc. Natl. Acad. Sci. U.S.A. 84, 2170-2174). Now we have found an alternative pathway for the metabolism of Ins(1,3,4)P3 in crude calf brain extracts. Along this pathway, Ins(1,3,4)P3 is first converted to Ins(1,3)P2 which is further hydrolyzed to Ins 1-P. This pathway involves a 4-phosphatase and a 3-phosphatase which do not require Mg2+ and are not inhibited by lithium ions. A similar 4-phosphatase also degrades Ins(3,4)P2 to Ins 3-P. Three different inositol bisphosphates formed from calf brain supernatant are each further metabolized by a separate enzyme. The three inositol monophosphates, i.e. Ins 1-P, Ins 3-P, and Ins 4-P, are converted to inositol by inositol monophosphate phosphatase (Ackermann, K. E., Gish, B. G., Honchar, M. P., and Sherman, W. R. (1987) Biochem. J. 242, 517-524).
Routing Heterogeneous Traffic in Delay Tolerant Satellite Networks (2022)

Delay Tolerant Networking (DTN) has been proposed as a new architecture to provide efficient store-carry-and-forward data transport in satellite networks. Since these networks relay on scheduled contact plans, the Contact Graph Routing (CGR) algorithm can be used to optimize routing and data delivery performance. However, in spite of the various improvements that have been made to CGR, there have been no significant proposals to prioritize traffic with different quality of service requirements. In this work we propose adaptations to CGR that allow performance improvements when sending traffic with different latency constraints, and develop a linear programming optimization model that works as a performance upper bound. The simulation results of the proposed schemes are promising and open the debate on other ways to improve performance while meeting the particular needs of heterogeneous traffic.
Development of a complementary PET/MR dual-modal imaging probe for targeting prostate-specific membrane antigen (PSMA) (2015)

The combination of using Positron Emission Tomography (PET) and computed tomography (CT) in clinical practice is now the norm. With advances in technology, the next step would be to develop combined PET and Magnetic Resonance (MR) dual-imaging. In this article, the authors described their positive study on the development of a dual-modal PET/MR imaging probe using a prostate cancer model.
Application of active disturbance rejection controller in wheeled mobile robot servo system (2014)

In wheeled mobile robot servo system, active disturbance rejection control (ADRC) technology is introduced and such controller is designed. It aims at solving the problems including complex external disturbances, changeful model parameters, contradiction between rapidity and overshoot as well as conventional control strategies depending heavily on high precise object model. For parameter tuning, the article presents an intelligent method based on the fusion of genetic algorithm and improved particle swarm optimization. The subsequent simulations prove ADRC performs better than PID control whether in static state with parameter perturbations and square wave disturbances or dynamic state of tracking sinusoidal reference signals. Experiments indicate that ADRC has a good robustness.
Cytocompatibility and 3D biodistribution with oxidized nanographene assessed by digital holographic microscopy (2021)

Nano graphene-based materials offer interesting physicochemical and biological properties for biotechnological applications due to their small size, large surface area and ability to interact with cells/tissues. Among carbon-based nanomaterials, graphene oxide is one of the most used in biological field. There is an increasing interest in shedding light on the interaction mechanisms of nanographene oxide (nGO) with cells. In fact, the effects on human health of GO, and its toxicological profile, are still largely unknown. Here we show that, by minimizing the oxidation degree of GO, its toxicity is significantly reduced in NIH 3T3 cells. Moreover, we show that mild oxidation of graphene nanoplatelets produces nGO particles, which are massively internalized into the cell cytoplasm. MTT(3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide) assay was performed to analyze cell viability. Transmission electron microscopy (TEM) analysis was performed to evaluate nGO internalization mechanism into the cytoplasm under different oxidation degree and concentrations. For the first time, we evaluated quantitatively, the cell volume variation after nGO internalization in live fibroblasts through a label-free digital holography (DH) imaging technique and in quasi-real-time modality, thus avoiding the time-consuming and detrimental procedures usually employed by electron-based microscopy. In conclusion, here we have demonstrated that DH can be a viable tool to visualize and display 3D distributions of nano graphene oxide (nGO) uptake by fibroblast cells. DH opens the route for high-throughput investigation at single cell level for understanding how in different conditions nanoparticles aggregates distribute inside the cells.
Oxidative modification of brain proteins in Alzheimer's disease and models thereof: role of amyloid beta-peptide (1- 42) and insights from redox proteomics (2007)

Click to launch & play an online audio visual presentation by Prof. D. Allan Butterfield on Oxidative modification of brain proteins in Alzheimer's disease and models thereof: role of amyloid beta-peptide (1- 42) and insights from redox proteomics, part of a collection of multimedia lectures.
Indoor fading distributions for GPS-based pseudolite signals (2007)

During the past few years, accurate positioning of terminals has received much attention in wireless communication. One reason is that of the requirement for emergency call positioning imposed by the authorities. The positioning algorithms based on the Navstar satellites have limitations in the indoor environment because the signal experiences severe attenuation in the indoor environment. The characteristics of the indoor propagation is still not well understood. In many cases, it is assumed that with the deployment of pseudolites, indoor navigation can show better performance. In this paper we analyze the indoor channel propagation using pseudolites, based on the measurement data collected in different scenarios.
Evidence for a Role of Topoisomerase II in the Ca2+-Dependent Basal Level Expression of the Rat Prolactin Gene (1988)

The PRL gene is expressed at a high basal level in rat pituitary tumor GH3 cells, and this basal level enhancement of PRL gene expression is maintained through a Ca2+-calmodulin-dependent mechanism. We have now examined whether the enzyme, DNA topoisomerase II, which has been shown to be phosphorylated by a Ca2+-calmodulin-dependent protein kinase, plays a role in the Ca2+-calmodulin-dependent basal level enhancement of PRL gene expression. The topoisomerase II inhibitor, novobiocin, at concentrations in the range of 35-140 microM, effectively blocked the ability of Ca2+ to increase PRL mRNA levels. Examination of the effects of novobiocin on the levels of protein synthesis, glucose-regulated protein (GRP) 78 mRNA, histone 3 mRNA, and 18S ribosomal RNA indicated that the drug selectivity inhibited PRL gene expression. Two other topoisomerase II inhibitors, m-AMSA and VM26, also diminished the Ca2+-induced levels of PRL mRNA at concentrations (100-400 nM) that did not lower total mRNA levels. We then examined whether topoisomerase II interacted nonrandomly with DNA from the 5' transcribed and 5'-flanking region of the rat PRL gene by in vitro mapping of topoisomerase II DNA cleavage sites. In initial assays with a 10.5 kilobase (kb) PRL genomic DNA fragment containing 3.5 kb of 5'-transcribed DNA and 7 kb of 5'-flanking DNA, we detected 4 major cleavage sites in the following regions: site 1, +1500 to +1600; site 2, +1 to -100; site 3, -1200 to -1300; and site 4, -2900 to -3000.(ABSTRACT TRUNCATED AT 250 WORDS)
Dewpoint Corrosion Resistance of Ni-Based High Performance Alloys (1997)

Abstract Recently, a new corrosion resistant Ni-Cr-Mo-Ta alloy, MAT-21, alloy T, was developed with improved corrosion resistance to sulfuric acid dewpoint corrosion which occurs in fossil fuel-fired power plants. Under conditions simulating acid dewpoint corrosion in waste incinerator flue gases, alloy T, which was composed of 19% chromium, 19% molybdenum, 1.8% tantalum and the balance nickel, was compared with the conventional Ni-based high performance alloys such as alloys C-276, 686 and 59. The corrosion tests showed that alloy T had excellent corrosion resistance to acid dewpoint corrosion in waste incinerators. The general and localized corrosion resistance behavior of alloys T, C-276, 686 and 59 was tested in different candidate solutions such as sulfuric acid and hydrochloric acid solutions, sulfuric-hydrochloric acid mixtures, hydrofluoric acid solutions in low concentrations, and the Green Death solution. Among these alloys, alloy T was the most resistant in these tests in the laboratory. Moreover, the corrosion resistance of welded joints of alloy T did not degrade in the as-welded condition.
Compact Millimeter-Wave CMOS Wideband Three-Transmission-Zeros Bandstop Filter Using a Single Coupled-Line Unit (2016)

This brief presents the design and implementation of millimeter-wave ultra-wide bandstop filter (BSF) using a standard 0.18-μm CMOS technology. The BSF configuration consists of a single coupled-line resonator shorted at the middle, which operates as not only a resonant element but also an open stub. The BSF realizes three transmission zeros in the stopband that results in sharp skirt selectivity. The overall width of the filter is less than the width of a 50-Ω line and occupies a compact area of 0.0066λ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">g</sub> × 0.443λ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">g</sub> , where λ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">g</sub> is the guided wavelength at 60 GHz. Explicit design equations are derived analytically using lossless transmission model. A prototype wideband BSF with a 3-dB bandwidth of 110% at 60 GHz is realized on a thin-film microstrip structure. The impact of several CMOS process parameters on the designed filter is also examined.
A high protein (HP) diet results in moderate renal and hepatic damage but improves body size, glucose handling and haptoglobin levels in diet‐induced obese rats (2013)

HP diets may aid in weight control and glucose handling, but also can cause minor damage to healthy kidneys. Since obesity itself increases renal damage, the additive effects of obesity and an HP diet were investigated in diet‐induced obese rats. Obesity‐prone and ‐resistant rats were given a high fat diet for 12 wk to induce obesity, followed by either HP [35 en%, ad libitum (AL)] or normal protein [35 en%, NP, either AL or pair‐weighed (PW)] for 8 wk. Obese rats given HP compared to NP diets AL consumed more feed but gained less weight. Renal enlargement in the HP compared to NP AL rats accompanied by higher proteinuria compared to NP AL and PW rats, and hepatic enlargement and elevated serum alanine aminotransferase in HP compared to PW NP rats indicated potential minor renal and hepatic damage. However, in addition to less weight gain, HP compared to NP AL rats also had lower blood glucose levels, homeostatic model assessment2 (HOMA2) scores and lower haptoglobin levels. Thus, the potential risks of HP feeding on minor renal and hepatic damage in obesity should be evaluated against the potential benefits on weight loss, glucose handling and inflammation. Grant Funding Source : CIHR 196330