gebhart/patrepeval huggingface dataset:
An evaluation method for college library Website based on evolutionary neural network (2012)

Library website is the window showing the service of modern college library. It is very important to evaluate the library website and improve its quality. In this study, the evaluation index system of library website is established firstly. Then, an intelligent method to evaluate college library website based on evolutionary neural network is proposed. An evaluation model of evolutionary neural network for college library website is founded. The illustrational results show that we can realize a fast and accurate evaluation for college library website by this method. It gives a beneficial academic reference to promote the construction quality of library website.
Optimum DCT-Based Multicarrier Transceivers for Frequency-Selective Channels (2006)

We derive on the impulse response and input signal of a frequency-selective finite impulse response channel to be diagonalized by the DCT into parallel, decoupled, and memoryless subchannels. We show how these conditions can be satisfied in a practical multicarrier transceiver through a novel design of the guard sequence and the front-end prefilter. This DCT-based design results in complete elimination of interblock and intercarrier interference without channel knowledge at the transmitter and at the same guard sequence overhead, compared with DFT-based multicarrier transceivers. Extensions to multi-input multi-output frequency-selective channels are also described. Finally, we present numerical examples from wireline and wireless communications scenarios to illustrate the viability and practicality of the DCT as a modulation/demodulation basis for baseband and passband signaling over frequency-selective channels.
Highly-dispersed Ta-oxide catalysts prepared by electrodeposition in a non-aqueous plating bath for polymer electrolyte fuel cell cathodes (2012)

The Ta-oxide cathode catalysts were prepared by electrodeposition in a non-aqueous solution. These catalysts showed excellent catalytic activity and have an onset potential of 0.92 V(RHE) for the oxygen reduction reaction (ORR). The highly-dispersed Ta species at the nanometer scale on the carbon black was an important contributor to the high activity.
BRAF Mutations in Low-Grade Serous Ovarian Cancer and Response to BRAF Inhibition (2018)

<i>BRAF</i> mutations are not uncommon in patients with LGSC and should be routinely tested, because BRAF inhibitors can be an effective treatment for these patients. The results highlight the need for targeted treatment in this rare tumor type, and a prospective study is needed to formally assess the response rate and clinical benefit.
OLED-on-CMOS based bidirectional microdisplay for near-to-eye and sensor applications (2011)

This paper presents a bidirectional OLED microdisplay with a monochrome 320×240 display and a nested image sensor with 160×120 pixels in 0.35 μm CMOS for near-to-eye and sensor applications.
Growth-controlled cubic zirconia microstructure in zirconia–titania nanolaminates (2002)

Zirconia microstructure selection (phase and crystallographic orientation) was studied in sputter-deposited multilayer films consisting of nanocrystalline ZrO2 and amorphous TiO2. The goal was to understand the mechanism for ZrO2 microstructure selection as a function of nanolaminate architecture (number of interfaces and ZrO2 and TiO2 layer thickness) in a growth regime of limited surface diffusion. The results show that there are two competing paths that ZrO2 microstructure can follow in a ZrO2–TiO2 nanolaminate. One path depends upon geometric shadowing resulting in the formation of a columnar morphology within a ZrO2 layer. This path leads to cubic (220) growth as an intermediate microstructure, and ultimately to the formation of cubic (200) crystallites spanning several bilayers. In this case, ZrO2 renucleation within a layer is suppressed. The second path depends upon renucleation within a ZrO2 layer, involving first tetragonal (111) formation, and then the transformation of tetragonal (111) to monoclinic(11-1)-(111), consistent with a finite crystal size effect. The establishment and maintenance of a columnar morphology (and hence, the suppression of renucleation events), ultimately leads to cubic (200) growth, and is consistent with a growth-controlled microstructure selection mechanism. This mechanism appears to strongly depend upon the existence and planar quality of the TiO2 growth–restart surfaces.
Akt Inhibits the Orphan Nuclear Receptor Nur77 and T-cell Apoptosis (2001)

Akt is a common mediator of cell survival in a variety of circumstances. Although some candidate Akt targets have been described, the function of Akt is not fully understood, particularly because of the cell type- and context-dependent apoptosis regulation. In this study, we demonstrate that one of the mechanisms by which Akt antagonizes apoptosis involves the inhibition of Nur77, a transcription factor implicated in T-cell receptor-mediated apoptosis. It has been suggested that Akt phosphorylates Nur77 directly, but whether Akt suppresses biological functions of Nur77 remains unknown. We found that Akt inhibited the DNA binding activity of Nur77 and stimulated its association with 14-3-3 in a phosphorylation site-dependent manner. Moreover, we found that expression of Akt suppressed Nur77-induced apoptosis in fibroblasts and activation-induced cell death of T-cell hybridomas. The inhibition of Nur77 by Akt suggests a mechanism that explains how T-cell receptor activation can promote survival in some instances even when Nur77 is induced. Collectively, these results may suggest that Akt is a negative regulator of Nur77 in T-cell apoptosis.
Towards a framework for evaluation of energy consumption, sustainability and associated food quality in the European cold chain (2011)

sponsorship: European Union FP7/2007-2013
From real-time attention assessment to “with-me-ness” in human-robot interaction (2016)

Measuring “how much the human is in the interaction” - the level of engagement - is instrumental in building effective interactive robots. Engagement, however, is a complex, multi-faceted cognitive mechanism that is only indirectly observable. This article formalizes with-me-ness as one of such indirect measures. With-me-ness, a concept borrowed from the field of Computer-Supported Collaborative Learning, measures in a well-defined way to what extent the human is with the robot over the course of an interactive task. As such, it is a meaningful precursor of engagement. We expose in this paper the full methodology, from real-time estimation of the human's focus of attention (relying on a novel, open-source, vision-based head pose estimator), to on-line computation of with-me-ness. We report as well on the experimental validation of this approach, using a naturalistic setup involving children during a complex robot-teaching task.
Wire-suspended dynamical system: stability analysis by tension-closure (2005)

Based on the linear complementarity formulation of a unilaterally inextensible wire model, the behavior of motion and stability of wire-suspended dynamical systems is addressed in this paper. The concept of tension properness is developed to determine kinematical motion property, particularly the instantaneous degrees-of-freedom. Further, motion determinacy in spite of tension indeterminacy is proven. The notion of tension closure is described to help analyze the stability behavior of wire-suspended dynamical systems. By analyzing the maximal closure-domain of relative tension closure, one can assess the stability behavior of wire-suspended systems qualitatively as well as somewhat quantitatively. Some numerical examples and simulations will clarify and corroborate the theoretical results of this paper.
Slice WIM (2011)

We present Slice WIM, a method for overview+detail visualization of volume datasets that explores the potential of new interfaces made possible by a virtual reality (VR) environment made of two display surfaces: an interactive multi-touch table, and a stereoscopic display wall. Slice WIM displays a miniature version of the 3D dataset within a head-tracked stereoscopic view such that it appears to float directly above the multi-touch table. Multi-touch gestures on the table are then used to navigate through the dataset and to set slices (cutting planes) through the data. Leveraging the unique table+wall hardware setup, horizontal slices through the data are projected (like a shadow) down onto the table surface, providing a useful 2D data overview to complement the 3D views as well as a data context for interpreting 2D multi-touch gestures made on the table. We demonstrate several strategies for interacting with 2D "shadow slices" on the table surface as a method for controlling the WIM and exploring volumetric datasets. Applications of the interface to explore two different volume datasets are presented, and design decisions and limitations are discussed along with feedback from both casual users and domain scientists.
Pretreatment nomogram predicting the long-term risk of metastatic progression of prostate cancer after radical prostatectomy (2005)

4545 Background: Biochemical recurrence as an endpoint for predictive models has been criticized as patients with a rising prostate specific antigen (PSA) level after definitive local therapy are not all at risk of dying from prostate cancer or suffering morbidity from recurrent disease. We have developed a preoperative nomogram that predicts the risk of metastatic disease after radical prostatectomy (RP). Methods: Between 1983 and 2002, 4590 consecutive patients with clinically localized prostate cancer underwent RP with (N=727) or without (N=3863) neoadjuvant androgen deprivation therapy (ADT). Information was obtained from a prospective database. The median follow-up for patients free of metastases was 61 months. Using Cox proportional hazards regression analysis, the disease characteristics and clinical follow-up were modeled to predict the probability of remaining free of metastases. The predictive accuracy of the nomogram was internally validated by means of bootstrapping. Results: Metastases developed in 209 patients (4.5%) overall, 95 of who received prior salvage ADT. The overall 13-year metastasis-free probability was 88% (95% confidence interval, 86–90). Significant variables in the multivariable model included pre-biopsy PSA (P=.0003), primary (P.0001) and secondary (P.0001) biopsy Gleason grade, clinical stage (P.0001), year of treatment (P=.0001) and neoadjuvant ADT (P=.002). Neoadjuvant ADT was an adverse predictor of metastatic progression (hazard ratio 1.7). The model was accurate and discriminating with a concordance index of 0.79. Conclusions: A preoperative nomogram has been developed that can be used to predict the 13-year probability of metastatic progression among men with clinically localized prostate cancer treated by RP. The nomogram is a useful tool for patient counseling and to identify high-risk patients for investigational neoadjuvant therapy. The adverse prognostic significance of neoadjuvant ADT for subsequent metastatic progression is an intriguing finding of our nomogram. Potentially, neoadjuvant ADT may diminish the response of prostate cancer to ADT when it is administered for progressive disease. No significant financial relationships to disclose.
ABSORPTIONS- UND STREUVERHALTEN BIOLOGISCHER GEWEBE BEZÜGLICH DER MONOCHROMATISCHEN OPTISCHEN STRAHLUNG (1979)

Article ABSORPTIONS- UND STREUVERHALTEN BIOLOGISCHER GEWEBE BEZÜGLICH DER MONOCHROMATISCHEN OPTISCHEN STRAHLUNG was published on January 1, 1979 in the journal Biomedical Engineering / Biomedizinische Technik (volume 24, issue s1).
Tuning the 1D–2D dimensionality upon ligand exchange in silver thiolate coordination polymers with photoemission switching (2023)

Silver nanoparticles are known and widely used for their antimicrobial activities. Nevertheless, once they are released into the natural or biological environments, they can become toxic with time, because of the dissolution of some Ag(I) ions that can then react with thiol-based molecules, such as glutathione and/or compete with copper proteins. These assumptions are based on the high affinity of the soft acid Ag(I) and the soft base thiolates and the exchange reactions that are involved in complex physiological media. Here we synthesized and fully characterized two new 2D silver thiolate coordination polymers (CPs) that exhibit a reversible 2D-to-1D structural transformation in the presence of an excess of thiol molecules. This dimensionality change induces also a switch of the yellow emission of the Ag-thiolate CP. This study highlights that these highly stable silver-thiolate CPs, in basic, acidic and oxidant media can undergo a complete dissolution-recrystallization mechanism upon thiol exchange reactions.
Genome-wide dynamic transcriptional profiling in clostridium beijerinckii NCIMB 8052 using single-nucleotide resolution RNA-Seq (2012)

The results from this work provided insights for further C. beijerinckii strain improvement employing system biology-based strategies and metabolic engineering approaches.
Intermediate atypical carcinoma (IAC): A discrete subtype of metastatic castration-resistant prostate cancer (mCRPC) suggesting that treatment-associated small cell/neuroendocrine prostate cancer (t-SCNC) may evolve from mCRPC adenocarcinoma (adeno)—Results from the SU2C/PCF/AACR West Coast Prostate Cancer Dream Team (WCDT). (2020)

158 Background: A subset of mCRPC patients (pts) that develop resistance to next-gen androgen signaling inhibitors are subsequently found to harbor t-SCNC. We have undertaken a longitudinal prospective biopsy (bx) study to clinically and molecularly characterize these pts. Methods: Eligible pts underwent an image-guided mCRPC bx at one of 5 WCDT centers. Tissue was both frozen and formalin fixed/paraffin embedded (FFPE). FFPE tissue was used for targeted next generation sequencing (NGS) and independent pathologic review by 3 pathologists. Frozen specimens underwent laser capture micro-dissection prior to RNA sequencing (seq). Machine learning was used to derive histology-specific expression signatures. Linear Discriminant Analysis (LDA) was applied to the RNA seq data from the first 131 bx using 3 observed histologic subtypes as labels to test for an intermediate subtype. Results: Of 391 mCRPC metastasis (53% bone, 26% node, 12% liver, 9% other soft tissue), 295(75%) yielded cancer. Overall, 89% of the bx contained a single histologic subtype: pure adeno in 156(53%); pure t-SCNC in 35(12%). A novel morphologically distinct subtype, IAC, with features of both tSCNC and adeno was seen in 72(24%). Samples comprised of two subtypes made up 32(11%) of all bx. Overall, 50(17%) of bx had a t-SCNC component. TP53 and/or RB1 loss of function variants were significantly more frequent in t-SCNC. NGS revealed no difference between adeno and IAC. LDA classified IAC as intermediate between adeno and t-SCNC 93% of the time, across 100 bootstrap replicates, significantly better than the 33% expected by chance (p &lt;10 −17 ). Conclusions: Nearly half of mCRPC bx exhibit non-adeno features with t-SCNC found in 17%. IAC is a reproducible mCRPC histologic subtype found in 24% of bx, with a gene expression signature that is intermediate to adeno and t-SCNC, and targeted NGS results similar to adeno. Understanding the role of IAC in disease evolution and resistance is critical for improving outcomes in mCRPC. Clinical trial information: NCT02432001.
ChemInform Abstract: Calculations of Solvation Free Energies in Chemistry and Biology. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A Review of Single-Mode Fiber Optofluidics (2015)

We review the field we describe as “single-mode fiber optofluidics” which combines the technologies of microfluidics with single-mode fiber optics for delivering new implementations of well-known single-mode optical fiber devices. The ability of a fluid to be easily shaped to different geometries plus the ability to have its optical properties easily changed via concentration changes or an applied electrical or magnetic field offers potential benefits such as no mechanical moving parts, miniaturization, increased sensitivity, and lower costs. However, device fabrication and operation can be more complex than in established single-mode fiber optic devices.
Remotely sensed plant height input to cotton growth model in GIS framework (2004)

The ability to predict yield in advance of harvest would be of great benefit to producers in terms of risk management and overall profitability. Crop growth models have proven to be useful, but they are not suited to use on a site-specific basis. Remote sensing provides site-specific data, but alone it is lacking in utility for producers. However, together these two technologies can conceivably provide for site-specific prediction of yield. A computer interface between the Arcview GIS (geographic information system) and the cotton growth model, Gossym, was developed to allow the model to accept inputs and provide predictive outputs on a site-specific basis. The relationship between remote-sensing data and cotton plant height was studied, and a means to input remote-sensing-based plant-height estimates to Gossym was implemented in the GIS interface. Based on this research, it appears to be reasonable to use remote-sensing data to estimate plant height, and then to use the estimate as real-world feedback to improve Gossym’s yield predictions. The results of this work facilitate the entire process of combining remote-sensing data with the cotton growth model, Gossym, in a GIS framework.
Behavioral signal processing for understanding (distressed) dyadic interactions (2011)

The expression and experience of human behavior manifestations are complex and are characterized by individual and contextual heterogeneity. Many domains rely on interpreting behavior -- especially those that are distressed and atypical -- through the available signals, both overt e.g., audio-visual data and covert e.g., heart rate. This paper describes the recent developments in behavioral signal processing aimed at understanding dyadic interactions in couple therapy.
Breast epithelial proliferation in postmenopausal women evaluated through fine-needle-aspiration cytology (2001)

We conclude that the FNA biopsy technique is feasible for studying proliferation not only in young, normally cycling women but also in the postmenopausal breast.
Characterization of the Particle Size and Polydispersity of Dicumarol Using Solid-State NMR Spectroscopy (2017)

A variety of particle sizes of a model compound, dicumarol, were prepared and characterized in order to investigate the correlation between particle size and solid-state NMR (SSNMR) proton spin-lattice relaxation (<sup>1</sup>H T<sub>1</sub>) times. Conventional laser diffraction and scanning electron microscopy were used as particle size measurement techniques and showed crystalline dicumarol samples with sizes ranging from tens of micrometers to a few micrometers. Dicumarol samples were prepared using both bottom-up and top-down particle size control approaches, via antisolvent microprecipitation and cryogrinding. It was observed that smaller particles of dicumarol generally had shorter <sup>1</sup>H T<sub>1</sub> times than larger ones. Additionally, cryomilled particles had the shortest <sup>1</sup>H T<sub>1</sub> times encountered (8 s). SSNMR <sup>1</sup>H T<sub>1</sub> times of all the samples were measured and showed as-received dicumarol to have a T<sub>1</sub> of 1500 s, whereas the <sup>1</sup>H T<sub>1</sub> times of the precipitated samples ranged from 20 to 80 s, with no apparent change in the physical form of dicumarol. Physical mixtures of different sized particles were also analyzed to determine the effect of sample inhomogeneity on <sup>1</sup>H T<sub>1</sub> values. Mixtures of cryoground and as-received dicumarol were clearly inhomogeneous as they did not fit well to a one-component relaxation model, but could be fit much better to a two-component model with both fast-and slow-relaxing regimes. Results indicate that samples of crystalline dicumarol containing two significantly different particle size populations could be deconvoluted solely based on their differences in <sup>1</sup>H T<sub>1</sub> times. Relative populations of each particle size regime could also be approximated using two-component fitting models. Using NMR theory on spin diffusion as a reference, and taking into account the presence of crystal defects, a model for the correlation between the particle size of dicumarol and its <sup>1</sup>H T<sub>1</sub> time was proposed.
Oxidation of tertiary amine buffers by copper(II) (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOxidation of tertiary amine buffers by copper(II)Fengjiang Wang and Lawrence M. SayreCite this: Inorg. Chem. 1989, 28, 2, 169–170Publication Date (Print):January 1, 1989Publication History Published online1 May 2002Published inissue 1 January 1989https://pubs.acs.org/doi/10.1021/ic00301a001https://doi.org/10.1021/ic00301a001research-articleACS PublicationsRequest reuse permissionsArticle Views565Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Incidence of HCV induced—Esophageal varices in Egypt (2017)

Esophageal varices is one of the most important comorbidity related liver cirrhosis, patients usually presented with hematemesis, melena, or both, ultimately 20% is the mortality during the first attack, hence we aimed to investigate the incidence of such esophageal varices related chronic Hepatitis C virus (HCV) in randomized Egyptian population.One thousand eighteen Egyptian patients, aged between 17 and 58 years, positive for Hepatitis C virus genotype 4 (HCV-4) by enzyme linked immunosorbent assay Ab and HCV RNA-polymerase chain reaction were screened for the presence of esophageal varices.Incidence of esophageal varices was 62.3%; 635 patients, those with large Esophageal varices (LEVs) was 47.4%; 301 patients. Model for end-stage liver disease (MELD) score has not been significantly improved post variceal band ligation (VBL). Using 2D U/S was useful for EVs prediction.Incidence of esophageal varices in HCV Egyptian patients still high, valuable knowledge would be helpful in clinical field have been discovered by data mining computational intelligent analysis using in practical medicine to improve overall health care.