gebhart/patrepeval huggingface dataset:
Facts Controllers in Power Transmission and Distribution (2009)

About the Book: The emerging technology of Flexible AC Transmission System (FACTS) enables planning and operation of power systems at minimum costs, without compromising security. This is based on modern high power electronic systems that provide fast controllability to ensure ''flexible'' operation under changing system conditions. This book presents a comprehensive treatment of the subject by discussing the operating principles, mathematical models, control design and issues that affect the applications. The concepts are explained often with illustrative examples and case studies. In partic
Detecting and Counting Oysters (2021)

Oysters are an essential species in the Chesapeake Bay living ecosystem. Oysters are filter feeders and considered the vacuum cleaners of the Chesapeake Bay that can considerably improve the Bay's water quality. Many oyster restoration programs have been initiated in the past decades and continued to date. Advancements in robotics and artificial intelligence have opened new opportunities for aquaculture. Drone-like ROVs with high maneuverability are getting more affordable and, if equipped with proper sensory devices, can monitor the oysters. This work presents our efforts for videography of the Chesapeake bay bottom using an ROV, constructing a database of oysters, implementing Mask R-CNN for detecting oysters, and counting their number in a video by tracking them.
In-vivo use of SIVmac239 with a reversing stop codon in the SIV nef gene (2020)

This letter is in response to a request from the Editor to provide additional information for readers on how the variant of SIV with a stop codon in the SIV nef gene used in the in-vivo studies published in 2015 [1] and 2017 [2] was created and the rationale for its use. The SIVmac239 stock used in these studies was created by assembling the two plasmids obtained from the NIH AIDS Reagent and Reference Program (p239SpSp5′ and p239Sp3′) according to the instructions provided by the submitter, Dr Desrosiers. The plasmid coding for the 3′-end of the virus constitutes a stop codon in nef that consistently reverts to an open genotype within 2 weeks postinfection in vivo but not in vitro. However, the virus stock created is highly replication-competent and pathogenic in rhesus macaques, leading to AIDS in 12–18 months, comparable with the original description of this molecular clone [3]. Of note, SIVmac239 with nef open is extremely virulent and often leads to uncontrolled acute viral replication and the death of many animals within 6 months postinfection without the ability of these animals to mount an antiviral adaptive immune response. Such a hypervirulent disease course is not representative of conventional human HIV infection. Acknowledgements Conflicts of interest There are no conflicts of interest.
Intricate structure of the interphase chromocenter revealed by the analysis of a factor involved in species formation (2018)

ABSTRACT In higher eukaryotes centromeres often coalesce into a large intranuclear domain called the chromocenter. Chromocenters are important for the organization of pericentric heterochromatin and a disturbance of their formation results in an upregulation of repetitive elements and causes defects in chromosome segregation. Mutations in the gene encoding for the centromere associated Drosophila speciation factor HMR show very similar phenotypes suggesting a role of HMR in chromocenter architecture and function. We performed confocal and super resolution microscopy as well as proximity based biotinylation experiments of HMR and its associated protein HP1a to generate a molecular map of HMR and HP1a bound chromatin. Our work reveals an intricate internal structure of the centromeric chromatin region, which suggests a role of HMR in separating heterochromatin from centromeric chromatin.
Data from Significant Association of Oncogene YAP1 with Poor Prognosis and Cetuximab Resistance in Colorectal Cancer Patients (2023)

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; Activation of YAP1, a novel oncogene in the Hippo pathway, has been observed in many cancers, including colorectal cancer. We investigated whether activation of YAP1 is significantly associated with prognosis or treatment outcomes in colorectal cancer.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; A gene expression signature reflecting YAP1 activation was identified in colorectal cancer cells, and patients with colorectal cancer were stratified into two groups according to this signature: activated YAP1 colorectal cancer (AYCC) or inactivated YAP1 colorectal cancer (IYCC). Stratified patients in five test cohorts were evaluated to determine the effect of the signature on colorectal cancer prognosis and response to cetuximab treatment.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt; The activated YAP1 signature was associated with poor prognosis for colorectal cancer in four independent patient cohorts with stage I–III disease (total &lt;i&gt;n&lt;/i&gt; = 1,028). In a multivariate analysis, the impact of the YAP1 signature on disease-free survival was independent of other clinical variables [hazard ratio (HR), 1.63; 95% confidence interval (CI), 1.25–2.13; &lt;i&gt;P&lt;/i&gt; &lt; 0.001]. In patients with stage IV colorectal cancer and wild-type KRAS, IYCC patients had a better disease control rate and progression-free survival (PFS) after cetuximab monotherapy than did AYCC patients; however, in patients with KRAS mutations, PFS duration after cetuximab monotherapy was not different between IYCC and AYCC patients. In multivariate analysis, the effect of YAP1 activation on PFS was independent of KRAS mutation status and other clinical variables (HR, 1.82; 95% CI, 1.05–3.16; &lt;i&gt;P&lt;/i&gt; = 0.03).&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusions:&lt;/b&gt; Activation of YAP1 is highly associated with poor prognosis for colorectal cancer and may be useful in identifying patients with metastatic colorectal cancer resistant to cetuximab. &lt;i&gt;Clin Cancer Res; 21(2); 357–64. ©2014 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;
Efficient Beamforming Designs for IRS-Aided DFRC Systems (2023)

This short tutorial presents several ideas for designing dual function radar communication (DFRC) systems aided by intelligent reflecting surfaces (IRS). These problems are highly nonlinear in the IRS parameter matrix, and further, the IRS parameters are subject to non-convex unit modulus constraints. We present classical semidefinite relaxation based methods, low-complexity minorization based optimization methods, low-complexity Riemannian manifold optimization methods, and near optimal branch and bound based methods.
Explication of object-oriented databases (1998)

The growing use of Object-Oriented Databases (OODBs) has necessitated the inclusion of OODBs in introductory database courses. Typically, such an analysis is conducted after the explication of the dominant industry standard: the Relational Database model (RDB). Like the RDB model, the OODB model can be easily motivated. Unlike the RDB model, an established data model with defined normal forms, the OODB model cannot be easily evaluated for "goodness". We address this deficiency by examining the criteria of coupling and cohesion in database design. This approach affords the instructor the ability to better present OODBs as well as the opportunity to re-emphasize critical software engineering concepts.
Uncertainty reduction in integrated control: Confronting model predictions with information from on-line data (2005)

Over the past 10-15 years WWTP control system performance has improved significantly by increased usage of on-line WWTP data. It is now time to extend the intensive use of on-line data to the sewer system, where on-line data can be used within control of both sewer and WWTP. A generic methodology for exploiting on-line sewer system data - as discussed in this paper - have revealed that these data seem as useful for good control as on-line WWTP data. Also, the integrated approach where sewer data are used for WWTP control and vice versa has proven successful and valuable. The critical step in using on-line sewer system data is to select sufficiently efficient methods for data reduction and information extraction. An approach to this is proposed, where on-line data are evaluated to distinguish between the stable dry weather situations and clear rain situations. This approach allows a fast identification of the catchment area and rainflows, for example in pumping stations. The use of the developed methods indicates that PST data provide more reliable information on the actual rain distribution than rain gauges.
Improved differentiation between knees with cartilage lesions and controls using 7T relaxation time mapping (2015)

T1<sub>ρ</sub> imaging at 7T has been established as a viable imaging method for the differentiation of degenerated cartilage despite previous concerns over specific absorption rate and imaging time. The potential increased sensitivity of T1<sub>ρ</sub> and T2 imaging at 7T may be useful for future studies in the development of OA.
ChemInform Abstract: 4‐(4,6‐Dimethoxy‐1,3,5‐triazin‐2‐yl)‐4‐methyl‐morpholinium Chloride: An Efficient Condensing Agent Leading to the Formation of Amides and Esters. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Radiation in Adolescent Idiopathic Scoliosis Management: Estimated Cumulative Pre-Operative, Intra-Operative, and Post-Operative Exposure (2022)

III, retrospective study.
Antihypertensive 2-amino-4(3H)-quinazolinones (1968)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAntihypertensive 2-amino-4(3H)-quinazolinonesHans J. Hess, Timothy H. Cronin, and Alexander ScriabineCite this: J. Med. Chem. 1968, 11, 1, 130–136Publication Date (Print):January 1, 1968Publication History Published online1 May 2002Published inissue 1 January 1968https://pubs.acs.org/doi/10.1021/jm00307a028https://doi.org/10.1021/jm00307a028research-articleACS PublicationsRequest reuse permissionsArticle Views1053Altmetric-Citations153LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The Role of Hypertonic Saline in Ablative Radiofrequency of the Sacroiliac Joint: Observational Study of 40 Patients (2022)

Bipolar RFA treatment of the sacroiliac joint with the use of a hypertonic saline solution appears to improve the success of the method and its durability. We are inclined to believe that the use of hypertonic saline may significantly increase the lesion area and result in a greater effect on the sensory branches.
Metabolic Disposition of Cytembena in Rats and Dogs (1977)

1. The metabolic disposition of cytembena (sodium cis-3-p-methoxybenzoyl-3-bromoacrylate)labelled at both carbonyl carbon atoms was studied in rats and dogs. 2. Rats excreted over 70% and dogs excreted over 50% of the radioactive dose in 24 h. Most of the radioactivity was found in urine. Kidney retained the highest level of radioactivity after 24 h. Renal cortex was responsible for the observed high retention. Both species exhibited similar tissue distribution and urinary metabolic patterns. 3. Cytembena was metabolized by demethylation catalysed by microsomes and by debromination and double bond saturation catalysed by the 100,000 g supernatant fraction in the presence of glutathione and NADPH. Tentative structures of the metabolites identified by mass spectrometry and the probable metabolic pathway of cytembena are presented,
Quality Control for Products Supplied with Warranty (1998)

A batch of products is to be supplied to customers with warranty. The units in the batch are either defective or nondefective, with different lifetime distributions. The defect rate—the proportion of defects in the batch—is itself a random variable, known only in terms of its distribution. We develop a sequential quality control procedure that exploits the knowledge of the defect distribution gained through inspection, and strikes an optimal balance between the inspection repair cost and the warranty cost. We identify a simple threshold policy, and we prove its optimality for a very general class of warranty cost functions without imposing any restrictions on the type of distributions involved. The key to optimality is that the warranty cost, as a function of the number of inspected units and the conditional defect index, satisfies a so-called K-submodularity property, which is a strengthening of the usual notion of submodularity.
Studies on rancidification of ground poppy-seed (2002)

To estimate the quality deterioration caused by lipid peroxidation in stored ground poppy-seed samples, the kinetic behaviour of different biochemical parameters characteristic of lipid peroxidation was studied and compared with flavour deterioration. It was found that the probability of rapid deterioration of samples is low when the change in AC values (the ratio of the values at the time of measurement and at the beginning of investigation) for peroxide values is a linear function of storage time and when lipoxygenase activity is low. When the kinetics is immediately non-linear and high activity of lipoxygenases is detected, the possibility of rapid quality deterioration can be anticipated.
Circulating miRNAs as Biomarkers for CYP2B6 Enzyme Activity (2020)

The CYP2B6 gene is highly polymorphic and its activity shows wide interindividual variability. However, substantial variability in CYP2B6 activity remains unexplained by the known CYP2B6 genetic variations. Circulating, cell-free micro RNAs (miRNAs) may serve as biomarkers of hepatic enzyme activity. CYP2B6 activity in 72 healthy volunteers was determined using the disposition of efavirenz as a probe drug. Circulating miRNA expression was quantified from baseline plasma samples. A linear model consisting of the effects of miRNA expression, genotype-determined metabolizer status, and demographic information was developed to predict CYP2B6 activity. Expression of 2,510 miRNAs were quantified out of which 7 miRNAs, together with the CYP2B6-genotypic metabolizer status and demographics, was shown to be predictive markers for CYP2B6 activity. The reproducibility of the model was evaluated by cross-validation. The average Pearson's correlation (R) between the predicted and observed maximum plasma concentration (C<sub>max</sub> ) ratios of efavirenz and its metabolite-8-OH efavirenz using the linear model with all features (7 miRNA + metabolizer status + age + sex + race) was 0.6702. Similar results were also observed using area under the curve (AUC) ratios (Pearson correlation's R = 0.6035). Thus, at least 36% (R<sup>2</sup> ) of the variability of in vivo CYP2B6 activity was explained using this model. This is a significant improvement over the models using only the genotype-based metabolizer status or the demographic information, which explained only 6% or less of the variability of in vivo CYP2B6 activity. Our results, therefore, demonstrate that circulating plasma miRNAs can be valuable biomarkers for in vivo CYP2B6 activity.
Use of Computational Methods to Aid in Transport Modeling. (2021)

Abstract not provided.
Diversity techniques for OFDM based WLAN systems (2003)

This paper presents different spatial diversity techniques that can be employed in an OFDM based WLAN system to improve the system performance. We present some results obtained by simulation when a HIPERLAN/2 transceiver is employed.
AgroNIT: Innovating Precision Agriculture (2022)

Major global concerns considering food production include, not only meeting the increasing food demand but also meeting challenges that put significantly less strain on the environment, safeguard food quality and prevent wastage. To address the erstwhile challenges, the AgroNIT testbed has been designed to provide common access to facilities and services fostering the development and the validation through experimentation of novel cultivation practices, as well as to enable the digital transformation of Agriculture by applying advanced cultivation methods with digital tools and connected machinery. In this paper, we describe how AgroNIT brings emerging digital technologies to the disposal of farmers and scientists in order to advance agriculture practices in multi-fold dimensions: From improving production yield to minimizing the crops' environmental footprint and the effective management of fertilizers and pesticides to the optimization of the irrigation processes tailored to the needs of each crop cultivar. In AgroNIT smart decision support systems provide real-time AI-generated consultancy to farmers by relying on sensors that automate field measurements collection. Furthermore, agricultural scientists have access to a large repository of data measurements and novel data analytic services, being able to design, apply – along with the farmers – and validate new cultivation protocols. We provide examples demonstrating specific experiments and we show how the AgroNIT testbed benefits both farmers and agricultural scientists, thus enabling next-generation precision agriculture.
A novel frequency compensation technique for low-voltage low-dropout regulator (2003)

A novel frequency compensation technique for low-voltage low-dropout regulator (LDR) is presented. The proposed technique, called pole-control frequency compensation (PCFC), provides faster loop response and does not require a large filtering capacitor. Both theoretical analysis and simulation show that the stability of the LDR using PCFC is independent of the load current, temperature and equivalent series resistance of the filtering capacitor. LDRs are well suited to portable equipment such as cellular phones, pagers and personal digital assistants.
Partition Coefficients of Proteins in Poly(ethylene glycol) + Dextran + Water at 298 K (1996)

The partition coefficients of lysozyme and bovine serum albumin in poly(ethylene glycol) + dextran + water at 298.15 K are reported. The investigation focuses on the variation of protein coefficients with pH and total polymer concentration at constant temperature and constant polymer molecular weight. In addition, liquid−liquid equilibrium for the water polymer systems at different total polymer concentration as well as the difference in density between the top and bottom phases has been measured.
Storing semistructured data with STORED (1999)

Systems for managing and querying semistructured-data sources often store data in proprietary object repositories or in a tagged-text format. We describe a technique that can use relational database management systems to store and manage semistructured data. Our technique relies on a mapping between the semistructured data model and the relational data model, expressed in a query language called STORED. When a semistructured data instance is given, a STORED mapping can be generated automatically using data-mining techniques. We are interested in applying STORED to XML data, which is an instance of semistructured data. We show how a document-type-descriptor (DTD), when present, can be exploited to further improve performance.
Towards Fingerprint Presentation Attack Detection Based on Short Wave Infrared Imaging and Spectral Signatures (2018)

Biometric verification systems are currently being deployed in numerous large-scale andeveryday applications. Among other vulnerabilities, presentation attacks directed to thesensor (e.g., using a face mask or a gummy finger) pose a severe security threat. To preventsuch attacks, presentation attack detection (PAD) techniques have been proposed in thelast decade. For the particular case of fingerprint recognition, most approaches are basedon conventional optical or capacitive sensors, acquiring a single image, and which can thusdetect only a limited number of materials used to fool the sensor.In this paper we propose a PAD algorithm based on normalised spectral signaturesextracted from ShortWave InfraRed (SWIR) images captured at four different wavelengths.It has been shown that the information contained in the selected SWIR wavelengths canhelp to discriminate skin from other materials. The extracted features are classified usinga Support Vector Machine (SVM), thereby yielding a fast real-time performance which canbe implemented on almost any application. The experimental evaluation shows that allbut one material considered can be detected, including unknown materials (i.e., not usedto train the classifier).
Intensive immunoablation and autologous blood stem cell transplantation in patients with refractory rheumatoid arthritis: the University of Nebraska experience. (2001)

Two patients with severe rheumatoid arthritis (RA) were treated with high dose chemotherapy and autologous blood stem cell transplantation. Hematopoietic stem cells mobilized readily with cyclophosphamide and granulocyte-colony stimulating factor. Both patients achieved an American College of Rheumatology (ACR) 50% response before starting high dose therapy. The transplantation regimen included 200 mg/kg cyclophosphamide and 6 doses of equine antithymocyte globulin. Transplantation was well tolerated and both patients recovered neutrophils on day 7 post-transplant. At one month post-transplant both patients had an ACR response of 80%. Both individuals relapsed at 6 months and responded well to a combination of disease modifying antirheumatic drugs that was previously ineffective. At 12 months ACR responses were 80% and 60%, respectively. The first patient developed a flare at 18 months when she was found to be hypothyroid; she regained an 80% ACR response at 24 months with therapy of hypothyroidism. The second patient progressed relentlessly 15 months post-transplant. Immunological reconstitution showed a continuous inversion of the ratio of CD4 and CD8 lymphocytes with a predominant expansion of memory T cells.