gebhart/patrepeval huggingface dataset:
Supplementary Figure 8 from KAT6B Is a Tumor Suppressor Histone H3 Lysine 23 Acetyltransferase Undergoing Genomic Loss in Small Cell Lung Cancer (2023)

&lt;p&gt;Supplementary Figure 8. Effect of KAT6B shRNA-mediated depletion in ATM expression and H2AX phosphorylation&lt;/p&gt;
WILLINGNESS-TO-PAY FOR VALUE ADDED BRED HEIFER CHARACTERISTICS (2003)

Willingness-to-Pay for Value Added Bred Heifer CharacteristicsThe cattle industry has developed a value based marketing system to meet changing consumer demand.However, cattle producer's management decisions are hindered because of their inability to source breeding stock of known quality.In 1997 The University of Missouri Department of Animal Science and College of Veterinary Medicine established a quality based bred heifer production program to educate and assist producers in enhancing the quality of bred heifers to be retained back into the herd or to be sold through the market place.Producers who participate in the Missouri Show-Me-Select Replacement Heifer Program follow a production protocol that ensures both quality and health requirements are met throughout the development of the calf into a bred heifer.Since the inception of this program 7,684 heifers have sold through sanctioned Show-Me-Select sales with gross receipts of $6,947,512.Program heifers typically sell at a price premium to non-program heifers.Yet, little is known about which quality
An Insight into the Features of the OAO-C Thermal Design (1973)

The Orbiting Astronomical Observatory (OAO)-C was successfully launched into 400-nautical mile circular orbit on August 21, 1972. For this spacecraft, a unique sensitivity approach to the thermal design was developed which resulted in a predictal design—the merits of which should be considered for application on future spacecra. The OAO-C is also serving as a test bed for the evaluation of thermal control hardware. To provide flight data for space program applications, experiments for a new coating and four different heat pipe designs are on this spacecraft. The data derived from OAO-C will be extremely valuable for such future programs as the Large Space Telescope (LST) and the Earth Observation Satellite (EOS). This paper will describe the detailed of the sensitivity design approach and thermal control hardware. For all aspects discussed, a comparison of pertinent analysis, ground test data, and flight data [1] will be given.
Aspekty ekstrakcji autorów na podstawie metadanych dokumentów (2011)

Prezentacja opisuje rozwiązanie kwestii braku powiązania autor-dzieło (kontrybucja). Omówione zostaje elastycznie rozszerzalne narzędzie służące do przeprowadzenia odzyskiwania w/w połączenia z wykorzystaniem metadanych. Opisano kolejne etapy działania narzędzia, jak również proponowane kierunki rozwoju.
Hybrid Beamforming Designs for Massive MIMO Millimeter-Wave Heterogeneous Systems (2017)

Network densification through the deployment of small cells along the coverage area of a macro-cell, employing massive multiple input multiple output (MIMO) and millimeter-wave (mmWave) technologies, is a key approach to enhancing the network capacity and coverage of future systems. For ultra-dense mmWave heterogeneous scenarios with a massive number of users, one should address both inter- and intra-tier interferences contrary to the low-density scenarios, where the network is mainly noise limited. Therefore, this paper proposes low complex hybrid analog-digital receive and transmit beamforming techniques for ultra-dense uplink massive MIMO mmWave heterogeneous systems to efficiently mitigate these interferences. At the small cells, the hybrid analog-digital receive beamforming/equalizer is computed in a distributed fashion, where the analog processing is performed at the small cell base stations or access points and the digital part at a central unit for joint processing. To optimize the analog part of the hybrid equalizer and the precoders used at the user terminals, we consider as a metric the distance relative to the fully digital counterpart induced by the Frobenius norm. In the optimization problem, apart from the analog constraints usually considered in the homogeneous systems, we further impose the constraints inherent to the distributed nature of the access points. To cancel the inter-tier interference, the digital parts of the precoders employed at the small cell user terminals are designed so that this interference resides in a low-dimensional subspace at the macro base station. The results show that the performance of the proposed hybrid analog-digital precoder/equalizer scheme is close to the fully digital counterpart and is able to efficiently remove both inter- and intra-tier interferences.
Synthesis and evaluation of constrained peptide analogues related to the N-terminal region of human growth hormone. (1992)

The synthesis and incorporation of two different isomeric gamma-lactam structures into peptide analogues related to hGH [6-13] are described. These peptide analogues and the corresponding aspartimide analogue have been tested for hypoglycemic activity with the intravenous insulin tolerance test. One lactam structure is of the type developed by Freidinger and co-workers, while the isomeric gamma-lactam structure represents a new constrained synthon for use in peptide synthesis. We have found that the hGH [6-13] peptide analogue incorporating the Freidinger lactam was more potent and longer lasting than the aspartimide peptide analogue. The hGH [6-13] peptide analogue incorporating the new gamma-lactam has diminished hypoglycemic activity. The relative biological activities of the three peptide analogues and the possible conformational implications at the physiological site of action are discussed.
Capacity of Multi-Antenna Gaussian Channels (1995)

We investigate the use of multiple transmitting and/or receiving antennas for single user communications over the additive Gaussian channel with and without fading. We derive formulas for the capacities and error exponents of such channels, and describe computational procedures to evaluate such formulas. We show that the potential gains of such multi-antenna systems over single-antenna systems is rather large under independence assumptions for the fades and noises at different receiving antennas.
A self-healing network with an economical spare-channel assignment (2002)

With the advent of networking technologies intelligent network elements, such as the digital cross-connect system (DCS), will make it possible to dynamically reconfigure a network for restoration purposes. Both restoration control of DCSs and spare-channel design issues are presented, and how they work together so that a fast and economical SONET self-healing network is obtained. In order to achieve fast restoration, a distributed control mechanism that is applicable to both line and path restoration is proposed. The proposed method allows the shared use of spare channels for various failure scenarios, including multiple failure cases, so that the efficient use of spare channels can be achieved. A linear-programming-based scheme is proposed to obtain spare-channel assignment, where a network-flow technique is used. Through a simulation study, a fast and economical self-healing network is verified.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Synthese und Eigenschaften von 6‐Desoxy‐6‐halogen‐Derivaten der L‐Ascorbinsäure (1980)

Synthesis and Properties of 6‐Deoxy‐6‐halogeno‐Derivatives of L ‐Ascorbic Acid 6‐Deoxy‐6‐chloro‐, ‐6‐bromo‐, ‐6‐iodo‐ and ‐6‐fluoro derivatives of L ‐ascorbic acid have been synthesized and characterized. The physiological properties of the chloro derivative have been investigated. It shows a high antiscurvy activity. The chloro‐ and bromo‐derivatives have been reduced to the corresponding deoxy compound, which is an interesting chiral intermediate for the preparation of rare ω‐deoxy sugars.
Structural, magnetic and magneto-transport properties of Pt-alloyed MnBi thin films (2010)

The structural, magnetic and magneto-transport properties of highly c-axis oriented Mn55−xPtxBi45 (x=0, 1.5, 3, and 4.5) thin films have been investigated. The coercivity of the Pt-alloyed thin films increases and the saturation magnetization decreases as the Pt concentration increases. The anisotropy field Ho increases as a function of Pt concentration, too but the coercivity increases more rapidly than the anisotropy field. This indicates an enhanced domain-wall pinning, caused by increased interstitial disorder due to the occupancy of regular Mn sites by Pt. The same mechanism explains the reduced magnetization. All samples exhibit a large extraordinary Hall effect with anomalous Hall coefficient about an order of magnitude larger than the ordinary Hall coefficient.
Initial assessment of a new approach for laser: tandem GMA welding (2012)

Recently a large number of research and development has been made regarding the use of Laser in welding operations, turning this process into an important tool for a variety of applications. Although it is possible to use Laser as a unique source of heat to promote union of materials, the combination of the beam provided by a Laser system with an arc welding process has become largely studied and applied in the so called hybrid welding. Generally, the final result of such combination is an increase in the weld penetration depth, width and welding travel speed. Despite all these facts, there are many issues still requiring further research and development concerning the use of hybrid welding using Laser and arc welding, including more comprehensive understanding on the various welding phenomena involved and the exploitation of new combinations. This paper describes a new approach for hybrid welding combining LBW with Tandem GMAW (Laser beam placed between the Tandem GMAW wires). The first view on such hybrid process variation is described and some basic aspects regarding its performance are discussed. The Laser beam had a positive effect on the aspect of the weld beads produced and a 10 mm inter-wire distance showed to be the most appropriate among the distances tried. Key words: hybrid welding, LBW, tandem GMAW.
Inducible Ribosomal RNA Methylation in Streptomyces lividans, Conferring Resistance to Lincomycin (1989)

Streptomyces lividans TK21 possesses inducible ribosomal RNA methylase activity that confers high-level resistance to lincomycin and lower levels of resistance to certain macrolides. The methylase gene (designated lrm) is inducible by erythromycin and other macrolides and also by celesticetin (a lincosamide) but not by lincomycin. The lrm enzyme monomethylates the N 6-amino group of adenosine at position 2058 within 23S-like ribosomal RNA.
Design of Switched Reluctance Motors and Development of a Universal Controller for Switched Reluctance and Permanent Magnet Brushless DC Motor Drives (2001)

Switched Reluctance Machines (SRMs) are receiving significant attention from industries in the last decade. They are extremely inexpensive, reliable and weigh less than other machines of comparable power outputs. Although the design principles of the machine are available as a concatenation of many different sources, the need for a unified, step-by-step design procedure from first principles of electromagnetics is an absolute requirement. This dissertation discusses a procedure that can be applied by engineers with a basic background in electromagnetics. Subsequent to the design of the machine, existing finite element software can do the analysis of the machine. However, this is a laborious process and the need for an analytical method is preferable to verify the design procedure before the final verification by finite elements. The analytical procedure as well as a procedure to calculate iron losses is also developed in this dissertation. A prototype machine has been developed as an example of the design process and an existing prototype is analyzed to verify the analysis procedure. The similarities between the SRM and the Permanent Magnet Brushless DC Machine (PMDBC) beg the consideration of the development of a converter that can be used to drive either machine. One such converter has been developed in this dissertation. The design of the drive for both the machines is seen to be very similar. As a consequence, a universal controller that can be used to operate both machines has been developed and implemented with a DSP. Simulations and experimental correlation for both drives have been presented.
Calculation of subaperture aspheric departure in lattice design for subaperture stitching interferometry (2010)

We demonstrate a method to solve the main problem involved in lattice design for subaperture stitching interferometry. That is calculation of the aspheric departure of a subaperture whose location is given arbitrarily. The simulated measurement data with unknown phase values are transformed into the global model frame, which satisfy the nominal surface equation. Then the phase values can be solved and used to calculate the aspheric departure with piston, tilts, and power removed. Accordingly, the subaperture lattice is determined with preferred interferometer parameters.
miR-125b Functions as a Key Mediator for Snail-induced Stem Cell Propagation and Chemoresistance (2012)

Chemoresistance is a major obstacle in cancer treatment. Our previous studies have shown that miR-125b plays an important role in chemoresistance. Here we report a novel mechanism that up-regulation of miR-125b through Wnt signaling by Snail enriches cancer stem cells. Overexpression of Snail dramatically increases the expression of miR-125b through the Snail-activated Wnt/β-catenin/TCF4 axis. Snail confers chemoresistance by repressing Bak1 through up-regulation of miR-125b. Restoring the expression of Bak1 or depleting miR-125b re-sensitizes Snail-expressing cancer cells to Taxol, indicating that miR-125b is critical in Snail-induced chemoresistance. Moreover, overexpression of miR-125b significantly increases the cancer stem cell population (CD24-CD44+), while depletion of miR-125b or rescue of the expression of Bak1 increases the non-stem cell population (CD24+CD44+) in Snail-overexpressing cells. These findings strongly support that miR-125b functions as a key mediator in Snail-induced cancer stem cell enrichment and chemoresistance. This novel mechanism for Snail-induced stem cell propagation and chemoresistance may have important implications in the development of strategies for overcoming cancer cell resistance to chemotherapy.
Le choix des matières plastiques (1972)

Les utilisateurs de matières plastiques éprouvent souvent beaucoup de difficultés à se retrouver dans la terminologie usitée dans le langage des plastiques et davantage encore à faire un choix parmi ceux-ci. Ceci d’autant plus qu’ils n’ont pas reçu de formation scolaire sur ces matériaux (les écoles d’ingénieurs n’abordent ce sujet que sous l’optique de la macrochimie et les écoles d’architectes n’ont pas encore atteint ce stade !) et que, de plus, volontairement ou non, on confond souvent les familles et les marques commerciales, ce qui accroît la confusion du non-spécialiste. Or, il n’existe qu’une vingtaine de familles plastiques actuellement développées ; le choix demeure donc encore facile si l’on sait opérer un classement fonctionnel de ces différentes matières. C’est ce que nous allons essayer de montrer.
A Virtual Over-the-Air Method for 5G Massive MIMO Base Station Testing With Flexible Virtual Probes (2019)

Massive multiple-input-multiple-output (MIMO) is known as a large-scale antenna technology and has been enabled for the fifth generation (5G) mobile communication systems. The over-the-air (OTA) testing of massive MIMO antenna system has attracted a lot of attention in terms of evaluating the radio performance of a 5G base station (BS). As a promising OTA test methodology, the sectored multi-probe anechoic chamber (MPAC) setup is employed for the performance testing of massive MIMO BS. However, the system cost and installation are still an issue to be considered in practice (e.g., the anechoic chamber and multiple probes), though it can accurately reconstruct the flexible propagation channels by channel emulation methods. This paper proposes a virtual OTA test framework for the performance testing of massive MIMO BS on the basis of MPAC setups. As an alternative, the proposed virtual OTA test system adopting the concept of virtual probes solves the inconveniences and limitations of the actual probe installation in MPAC setups. The BS array responses to the actual probes of MPAC setups are generated in a phase matrix for the virtual probes. First, in this paper, the system description of virtual OTA testing is given. Then, the emulation method of spatial clusters is presented for the virtual OTA testing. Finally, simulations are performed with good channel emulation accuracy.
Enantio‐ and Diastereoselective Construction of α,α‐Disubstituted α‐Amino Acids for the Synthesis of Biologically Active Compounds. (2006)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Effect of Montage on the Analgesic Response to Percutaneous Neuromodulation Therapy (2001)

The analgesic response to percutaneous neuromodulation therapy (PNT) is influenced by the location, frequency, and duration of electrical stimulation. We evaluated the effect of different patterns of stimulation (montages) on the acute analgesic response to PNT when applied at the same dermatomal levels in 72 consenting patients with low back pain. All of the patients received a standardized montage (I) and three alternative montage (II–IV) patterns according to a randomized, single-blinded, crossover study design. All of the PNT treatments were administered at identical alternating stimulation frequencies of 15 and 30 Hz for a period of 30 min, three times per week for two consecutive weeks, with 1 wk “off” between each modality. Pretreatment assessments included the health status survey short form (SF-36) questionnaire, as well as visual analog scale scores for pain, physical activity, and quality of sleep (with 0 = the best to 10 = the worst). The pain visual analog scale was repeated 5–10 min after each treatment session. The daily oral analgesic usage was recorded in a patient diary. All four montages produced significant improvements in pain (42%–64%), physical activity (35%–51%), and quality of sleep (28%–46%), as well as 23% to 47% reductions in the daily oral analgesic usage. However, Montage II was significantly more effective than the standard (Montage I) and the other two montages studied. These data suggest that the pattern of stimulation (i.e., montage) can influence the acute analgesic response to PNT. Implications With electroanalgesic techniques such as percutaneous neuromodulation therapy, the pattern of the electrical stimulation can influence the acute analgesic response even when identical stimuli are administered at the same dermatomal levels.
Nucleation and Growth of Cobalt Films on NaCl. I. Effects of Evaporation Rate and Surface Morphology (1971)

Cobalt thin films, which are stable in both the f.c.c. and h.c.p. structures, nucleate and grow through a process of coalescence and recrystallization when deposited on clean NaCl substrates (i.e., free of gaseous contamination) at 350 °C in much the same manner as other f.c.c. metals deposited on NaCl. Cobalt nuclei are stable in four distinct orientations characterized by having (001), (00.1), (211), or (110) planes of the nuclei parallel to the substrate; in each case the close-packed directions in the plane of the nucleus are parallel to the close-packed directions in the substrate. The final crystal structure and orientation of the films is dependent upon changes occurring during film growth as a result of coalescence and recrystallization phenomena. These are governed by evaporation rate and nucleation rate, the latter being determined by the number of preferred adsorption sites on the substrate (small cleavage steps), other deposition conditions remaining the same. When there is little time during growth for coalescence and recrystallization in the discontinuous films (at high evaporation and nucleation rates), films containing abnormally large hexagonal grains having a (00.1) fibre texture in a matrix of smaller grains having the four preferred orientations of the initial nuclei result. When coalescence and recrystallization in the discontinuous films occur, the final continuous film is epitaxial. Dünne Kobaltschichten, die sowohl in der k.f.z. als auch in der h.d.p.-Struktur stabil sind, bilden Keime und wachsen durch einen Koaleszenzprozeß und Rekristallisation, wenn sie auf saubere NaCl-Substrate (d. h. frei von Gaskontamination) bei 350 °C aufgebracht werden, in ganz derselben Weise, wie andere k.f.z.-Metalle, die auf NaCl aufgebracht werden. Kobaltkeime sind bei vier verschiedenen Orientierungen stabil, die dadurch charakterisiert sind, daß die (001)-, (00.1)-, (211)-oder (110)-Ebenen der Keime parallel zum Substrat liegen. In jedem Fall sind die dichtgepackten Richtungen in der Keimebene parallel zu den dichtgepackten Richtungen im Substrat. Die endgültige Kristallstruktur und- orientierung der Schichten hängt von Änderungen ab, die während des Schichtwachstums als Ergebnis von Koaleszenz- und Rekristallisationseffekten auftreten. Diese werden durch die Aufdampfrate und Keimbildungsrate gesteuert, die letztere wird durch die Zahl der bevorzugten Adsorptionsplätze auf dem Substrat (kleine Spaltstufen) bestimmt, wobei die anderen Aufdampfbedingungen die gleichen bleiben. Wenn wenig Zeit während des Wachstums für Koaleszenz und Rekristallisation in den diskontinuierlichen Schichten vorhanden ist (bei hohen Aufdampf- und Keimbildungsraten) ergeben sich Schichten, die anomal große, hexagonale Kristallite mit einer (00.1) Fibertextur in einer Matrix von kleineren Kristalliten, die die vier bevorzugten Orientierungen der ursprünglichen Keime besitzen, enthalten. Wenn Koaleszenz und Rekristallisation in diskontinuierlichen Schichten auftreten, ist die endgültige kontinuierliche Schicht epitaxial.