gebhart/patrepeval huggingface dataset:
Further evidence for the stimulation of rat brain dopamine receptors by ergometrine (1974)

Journal Article Further evidence for the stimulation of rat brain dopamine receptors by ergometrine Get access G N Woodruff, G N Woodruff Department of Physiology and Biochemistry, University of Southampton, Medical & Biological Sciences Building, Bassett Crescent East, Southampton SO9 3TU, UK Search for other works by this author on: Oxford Academic Google Scholar A O Elkhawad, A O Elkhawad Department of Physiology and Biochemistry, University of Southampton, Medical & Biological Sciences Building, Bassett Crescent East, Southampton SO9 3TU, UK Search for other works by this author on: Oxford Academic Google Scholar A R Crossman A R Crossman Department of Physiology and Biochemistry, University of Southampton, Medical & Biological Sciences Building, Bassett Crescent East, Southampton SO9 3TU, UK Search for other works by this author on: Oxford Academic Google Scholar Journal of Pharmacy and Pharmacology, Volume 26, Issue 6, June 1974, Pages 455–456, https://doi.org/10.1111/j.2042-7158.1974.tb09313.x Published: 12 April 2011 Article history Received: 18 January 1974 Published: 12 April 2011
A shallow-trench-isolation flash memory technology with a source-bias programming method (2002)

A flash memory cell with a self-aligned shallow-trench isolation structure and a novel source-bias programming method has been developed. Using a shallow-trench technology to form field isolation between the memory cells results in high-voltage parasitic transistor characteristics and enables the isolation structure to be fabricated at low temperature, which leads to high endurance. By applying a positive bias to the source terminal during programming, the programming speed is maintained even for short-channel-length memory cells with a low drain-source breakdown voltage.
A 3D virtual environment for social telepresence (2002)

We examine OnLive Traveler as a case study. Traveler is a clientserver application allowing real-time synchronous communication between individuals over the Internet. The Traveler client interface presents the user with a shared virtual 3D world, in which participants are represented by avatars. The primary mode of communication is through multi-point, full duplex voice, managed by the server. Our design goal was to develop a virtual community system that emulates natural social paradigms, allowing the participants to sense a tele-presence, the subjective sensation that remote users are actually co-located within a virtual space. Once this level of immersive "sense of presence" and engagement is achieved, we believe an enhanced level of socialization, learning, and communication are achievable. We examine a number of very specific design and implementation decisions that were made to achieve this goal within platform constraints. We also will detail some observed results gleaned from the virtual community userbase, which has been online for several years
Patient Perceptions in Mast Cell Disorders (2018)

Understanding experiences, perceptions, and perspectives of patients with a mast cell disorder (MCD), including cutaneous mastocytosis, systemic mastocytosis, mast cell activation syndromes, and hereditary α-tryptasemia, is an important aspect of successful care, treatment, and informed development of novel therapies. This article reviews existing studies and presents new data on MCD patient perceptions regarding medical care, symptoms, allergies/sensitivities, triggers, future health/disease progression, treatment, impact on daily living, quality of life, support needs, and concerns regarding possible familial disease. Discussion includes aspects affecting the MCD community that require further consideration and development.
Improving Performance by Doping Gadolinium Into the Indium-Tin–Oxide Electrode in HfO2-Based Resistive Random Access Memory (2016)

This letter investigates the characteristics of doping gadolinium (Gd) in an indium-tin-oxide (ITO) electrode in HfO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> -based resistive random access memory (RRAM). Identical bottom electrodes and insulators were made but then capped by either pure ITO or a Gd:ITO top electrode. Doping Gd in the ITO electrode produces lower operation currents in both high-resistance state (HRS) and low-resistance state (LRS) as well as enlarging the memory window. This excellent performance suggests a remarkable potential to improve RRAM applications. Schottky emission mechanism dominates both HRS and LRS according to current fitting results, and is confirmed by temperature effect experiments. The resistive switching behavior of the Gd:ITO device is explained by our model and is also confirmed by material analysis and electrical measurements. Furthermore, reliability tests verify the Gd:ITO device's capability to perform data storage as a nonvolatile memory.
Antibody to Immunoglobulin G and Polyethylene Glycol Augment Cyclic Adenosine Monophosphate Production by TSH Receptor Antibody Bound to Porcine Thyroid Cells (2004)

Anti-immunoglobulin G (IgG) augments cyclic adenosine monophosphate (cAMP) production by thyroid-blocking antibody (TBAb) bound to porcine thyroid cells (PTC). This is described as a conversion phenomenon. We reported the effect of polyethylene glycol (PEG) to augment thyroid-stimulating antibody (TSAb) activity in a PTC assay. In the present experiment we examined the effect of anti-immunoglobulin G (IgG) and PEG on cAMP production from TBAb or TSAb bound to PTC. TBAb bound to PTC was separated from unbound TBAb by centrifugation after a first incubation (0.5 hour at 37 degrees C) of TBAb-IgG with PTC. TBAb bound to PTC were incubated with anti-human (h)IgG or hIgG fragments [F(ab')(2), Fc, Fd, H chain or L-chain] for 4 hours at 37 degrees C in the second incubation. Anti-IgG or anti-IgG fragments increased cAMP production. No conversion was caused by protein A, protein L, or PEG (5%). PEG did not augment cAMP production by these IgG antibodies. PEG augmented cAMP production during incubation of TSAb-IgG bound to PTC, but anti-IgG did not. PEG significantly augmented cAMP production by coincubation of TSAb-IgG bound to PTC and the unbound TSAb-IgG (obtained from the first incubation). A similar augmentative effect of PEG was also observed in experiments using TSAb-F(ab')(2) and TSAb-Fab. cAMP production by PTC bound by both TBAb- and TSAb-IgG was increased by co-incubation with anti-IgG, but was not increased by PEG. In conclusion, anti-IgG specifically increased cAMP production from TBAb bound to PTC (conversion phenomenon) and PEG specifically increased cAMP production by TSAb bound to PTC. Different mechanisms enhance cAMP production by TSAb and conversion of TBAb.
Naming the Dead - Confronting the Realities of Rapid Identification of Degraded Skeletal Remains. (2004)

The Armed Forces DNA Identification Laboratory (AFDIL) is one of the leading laboratories in the world for the processing of degraded skeletal remains. Extended efforts have been made to develop protocols and standards that will hold up to the intense scrutiny of both the scientific world and the U.S. legal system. Presented in this paper are the specifics of the in-house systems and procedures that have allowed AFDIL to streamline the processing of degraded skeletal remains and family references for mitochondrial DNA (mtDNA) analysis. These include the development of our in-house bioinformatics systems by which every package and sample that passes through the laboratory is tracked; protocols designed specifically for both questioned and reference samples; and the difficulties inherent in this type of organization. Two case studies presented involve one of ancient remains and one on the recent event of September 11, 2001. Finally, future directions available to both AFDIL and the DNA analysis community as a whole are discussed.
Staphylococcus epidermidis recovered from indwelling catheters exhibit enhanced biofilm dispersal and “self-renewal” through downregulation of agr (2012)

Collectively, these data reveal the role of agr system in long-term biofilm development and pathogenesis during Se caused indwelling devices-related relapsed infection.
Ehrlichia chaffeensisInfection of Sika Deer, Japan (2009)

To determine whether Ehrlichia chaffeensis exists in Japan, we used PCR to examine blood from sika deer in Nara, Japan. Of 117 deer, 36 (31%) were infected with E. chaffeensis. The E. chaffeensis 16S rRNA base and GroEL amino acid sequences from Japan were most closely related to those of E. chaffeensis Arkansas.
Severe hypoxia affects exercise performance independently of afferent feedback and peripheral fatigue (2012)

To test the hypothesis that hypoxia centrally affects performance independently of afferent feedback and peripheral fatigue, we conducted two experiments under complete vascular occlusion of the exercising muscle under different systemic O(2) environmental conditions. In experiment 1, 12 subjects performed repeated submaximal isometric contractions of the elbow flexor to exhaustion (RCTE) with inspired O(2) fraction fixed at 9% (severe hypoxia, SevHyp), 14% (moderate hypoxia, ModHyp), 21% (normoxia, Norm), or 30% (hyperoxia, Hyper). The number of contractions (performance), muscle (biceps brachii), and prefrontal near-infrared spectroscopy (NIRS) parameters and high-frequency paired-pulse (PS100) evoked responses to electrical muscle stimulation were monitored. In experiment 2, 10 subjects performed another RCTE in SevHyp and Norm conditions in which the number of contractions, biceps brachii electromyography responses to electrical nerve stimulation (M wave), and transcranial magnetic stimulation responses (motor-evoked potentials, MEP, and cortical silent period, CSP) were recorded. Performance during RCTE was significantly reduced by 10-15% in SevHyp (arterial O(2) saturation, SpO(2) = ∼75%) compared with ModHyp (SpO(2) = ∼90%) or Norm/Hyper (SpO(2) > 97%). Performance reduction in SevHyp occurred despite similar 1) metabolic (muscle NIRS parameters) and functional (changes in PS100 and M wave) muscle states and 2) MEP and CSP responses, suggesting comparable corticospinal excitability and spinal and cortical inhibition between SevHyp and Norm. It is concluded that, in SevHyp, performance and central drive can be altered independently of afferent feedback and peripheral fatigue. It is concluded that submaximal performance in SevHyp is partly reduced by a mechanism related directly to brain oxygenation.
Experimental demonstration of multiple Fano resonances appearing due to the interaction of plasmonic mode with waveguide modes in a mirrored array of split-ring resonators (2022)

Abstract This work demonstrates the first experimental observation of multiple Fano resonances in the terahertz range in a system based on an array of mirror-symmetric split-ring resonators deposited on low-loss and low-refractive index polytetrafluoroethylene (PTFE) substrate. For the first time, selective surface activation induced by laser technology has been used to deposit a copper layer on a PTFE substrate with the further application of standard mask lithography for metasurface manufacturing.
In-Process Measurement and Workpiece-Referred Form Accuracy Control (6th Report) (1998)

In the previous reports, the author proposed a new system, named the Workpiece-Referred Form Accuracy Control System (WORFAC), and confirmed an effectiveness of this method. In the 3rd to 5th reports, this method was applied to the cylindrical turning by an ordinary, lathe and it was found that the WORFAC is useful to improve the cutting accuracy of ordinary lathe and that the simulation and experiment are well consistent. In this report, the WORFAC is applied to face turning and obtained following results : (1) The offset of a sensor in the cutting direction can be heaped up and it may cause to make some errors. It can be avoided if the cutting control is started at the time when a sensor and a tool reach on the same concentric circle on the workpiece surface. (2) Let xs, yg are two dimensional offsets of the sensor from the cutting point on the workpiece surface as xg for the feed direction. The form accuracy is getting better as yg is bigger for the area of xg>yg. (3) At the area of yg≥xg being yg smaller, the form is better. The best position is yg=xg.
Tumor‐inhibiting platinum(II) complexes with aminoalcohol ligands: Comparison of the mode of action by capillary electrophoresis and electrospray ionization‐mass spectrometry (2003)

Capillary electrophoresis (CE) was used as an assay for studying the interaction of (SP-4-2)-bis[(R)-(-)-2-aminobutanol)dichloroplatinum(II) (1) and (SP-4-2)bis(4-aminobutanol)dichloroplatinum(II) (2) with guanosine 5'-monophosphate (GMP). CE kinetic measurements carried out at two physiological pH levels indicated that upon increasing the pH, 1 showed an appreciable change in binding behavior, with the rate of binding increased for more than 10 times as expressed by apparent half-life values of GMP (6.1 and 62.2 h at pH 6.0 and 7.4, respectively). The rate of GMP binding for 2 remained comparatively less affected by pH (half-lives of 8.5 and 10.6 h, respectively). Regardless of the nature of platinum complex and pH, the reaction with GMP tends to be decelerated at increased chloride concentrations in solution, this effect being particularly pronounced when changing from 4 mM (intracellular level) to 100 mM (extracellular level). The kinetic differences of platinum complexes were characterized in terms of the respective GMP-adducts structure, independently identified by means of off-line electrospray ionization-mass spectrometry. Also addressed was the interpretation of binding behavior as based on the structural features of the intact complexes, namely differing inclination to intramolecular chelation.
Ischemic mitral valve regurgitation grade II-III: correction in patients with impaired left ventricular function undergoing simultaneous coronary revascularization. (2001)

Both MV repair and replacement preserving subvalvular apparatus in patients with impaired LV function offered acceptable outcome in terms of morbidity and survival. Surgical correction of grade II-III MVR in patients with impaired LV function should be taken into consideration as it provides better survival and improves LV function.
Striped‐pattern deterioration and morphological analysis of injection molding comprising polypropylene/ethylene–α‐olefin rubber blends. II. Influence of heating (2007)

Abstract Unique deterioration with a striped pattern caused by thermal heating is reported for injection molding comprising polypropylene/ethylene–α‐olefin rubber blends. This stripe is due to the formation of glossy and cloudy parts in alternation approximately perpendicular to the flow direction of the molten resin. On the surface of the cloudy part, a number of micro‐objects appear. They have a dome shape about 10 μm in diameter and 2 μm height. Some experimental evidence indicates that the objects are composed of the rubber contained in the blends. On the other hand, only a few objects appear in the glossy region after heating. This is the reason that the stripe with the micro‐objects (migrating rubber to the surface) is examined in terms of a higher order structure of injection molding with laser scanning microscopy, wide‐angle X‐ray scattering, and microhardness (Martens hardness). Consequently, we have concluded that this thermally deteriorated stripe depends on periodic changes in the crystallinity along the flow direction. The evidence indicates that a snakelike flow occurs during the injection process of the molding. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci 2008
A review of environmental assessment for greenhouse gas-intensive projects (1998)

Currently the Bank operational policies require that a project have its greenhouse gas (GHG emissions, fully assessed, and taken into account in project design, and selection. However, it is suspected that very few projects have GHG emissions analysis in the project environmental assessment. Concerns about the suspected low rate of compliance, made evaluators question whether the importance of GHG emissions abatement practice was underestimated, or if the Bank did not provide the appropriate for project-level GHG emissions analyses. These questions led to this study. To this end, the objectives of the study are to: 1. determine the compliance rate of GHG-intensive projects to those policies; 2. investigate the reasons for apparent non-compliance; 3. gather suggestions from operational staff to improve the level of compliance; and, 4. establish specific recommendations. The methodology sued was to document review, and interviews. The study suggests that to encourage compliance in the GHG analysis, the Bank should: disseminate more scientific, and statistical research, showing the correlation between global GHG emissions, and individual project activities; develop guidelines for GHG emissions analysis at the project operation level; train staff to ensure consistency; and, disseminate examples of high-quality GHG emissions analyses.
Treatment of chronic HCV infection in compensated and decompensated cirrhosis (2004)

Abstract Currently, we are faced with an increasing number of patients with HCV‐induced end‐stage liver disease. Per year, up to 4% of the patients with compensated cirrhosis develop complications subsequently leading to a substantial decrease in survival. Decompensated liver cirrhosis due to hepatitis C is the leading indication for liver transplantation (OLT). However, reinfection of the graft is common with an accelerated course of the disease in many patients. Depending on the disease stage, the aims of antiviral therapy may differ between patients with HCV‐induced liver cirrhosis. Antiviral therapy can reverse the extent of fibrosis. Even without viral clearance, the incidence of hepatocellular carcinoma is lowered by interferon. In naïve patients with compensated HCV‐induced cirrhosis, sustained virological responses can be achieved in up to 50% of the cases. Retreatment of non‐responders may clear the virus in about 10% of the patients. Though elimination of HCV prior to OLT is certainly desirable, treatment is often limited by severe cytopenia and decompensation of liver function. Of the eligible patients 20% sustain viral clearance after OLT.
Session 4 ‐ Markets, Media and Meanings Simon Roberts (Intel, Ireland), Curator: Lead Type, Dead Type: New Patterns of Local News Production and Consumption (2009)

Newspapers are in trouble. Steep declines in circulation and advertising revenue have forced outright closures, reductions in force, cessation of print in favor of web only editions and frantic searches for additional sources of revenue and audience. In this paper, we report results from an interview study focused on everyday news consumption practices. Our study indicates there are many design opportunities for local news creation and distribution at interface/interaction, infrastructure and strategy levels.
A direct competitive enzyme-linked immunosorbent assay for rapid detection of anilofos residues in agricultural products and environmental samples (2012)

A direct competitive enzyme-linked immunosorbent assay (dc-ELISA) was developed to measure anilofos levels in agricultural and environmental samples. The ELISA was developed using rabbit polyclonal antibodies against a hapten-protein conjugate of anilofos-bovine serum albumin. The limit of detection was 0.1 μg L(-1), and there was no cross-reactivity with other related pesticides or structurally similar compounds. The matrix effects of rice (aromatic rice, white rice, brown rice), corn, barley, wheat and soil were measured and removed by extraction and dilution with phosphate buffered saline with 0.05% Tween-20. For water samples (tap water and river water), the matrix effects were also removed by dilution with phosphate buffered saline with Tween-20. The detection limits for anilofos in authentic samples (aromatic rice, white rice, brown rice, corn, barley, wheat, soil, tap water and river water) were 2, 2, 2, 3, 2, 2, and 2 μg kg(-1), and 0.5 and 1 μg L(-1), respectively . The anilofos recovery ranged from 81.0-116.0% with a coefficient of variation of 1.7-9.0%. The method was validated using GC, and the results showed good correlation with the dc-ELISA data (r(2) = 0.9795). Forty-two cereal samples were randomly collected from different supermarkets and analyzed using the developed dc-ELISA. No anilofos was found in these products. The developed immunoassay is suitable for rapid quantitation of anilofos residues.
INDUCTION OF α-AMYLASE OF BACILLUS STEAROTHERMOPHILUS BY MALTODEXTRINS (1963)

Welker, N. E. (Western Reserve University, Cleveland, Ohio) and L. Leon Campbell. Induction of alpha-amylase of Bacillus stearothermophilus by maltodextrins. J. Bacteriol. 86:687-691. 1963.-Technical-grade maltose contained 3.5% glucose, 0.5% maltotriose, and 2.5% of the higher molecular weight maltodextrins. The first five homologues (maltose being the first in the series) of the maltodextrin series were isolated and purified. Each member of the series was found to be chromatographically pure. The physical and chemical properties were determined. It was shown that the contaminating maltodextrins found in technical grade maltose were linear (1-4 linked) polymers of glucose, ranging from maltotriose to maltohexaose. The addition of maltose, maltotriose, maltohexaose, maltopentaose, and maltotetraose (all at 10(-4)m) to cultures growing in a chemically defined medium resulted in a stimulation in the differential rate of alpha-amylase synthesis by 1.2, 1.6, 1.9, 2.3, and 3.0 times that of the sucrose control, while glucose had no effect. The induction data indicate that Bacillus stearothermophilus 1503-4 is a partial constitutive strain with respect to alpha-amylase synthesis.
Nanograssed Zigzag Structures To Promote Coalescence-Induced Droplet Jumping (2019)

To increase the efficiency of jumping-droplet condensation, this study proposes a hierarchical superhydrophobic surface that promotes coalescence-induced jumping. Inspired by the phenomenon in which a growing droplet moves spontaneously within a superhydrophobic V structure, we fabricated nanograssed zigzag structures on the surface to induce the spontaneous motion of condensed droplets. The direction of the motion was parallel to the surface, so the condensed droplets easily coalesced on it. Compared with a conventional nanograssed superhydrophobic surface, the proposed surface increased the frequency of coalescence-induced jumping by ≥17 times and increased the cumulative volume of jumping droplets by ∼1.8 times. The proposed surface has great potential to increase the efficiency of applications such as water- and energy-harvesting and cooling systems that exploit jumping-droplet condensation.