gebhart/patrepeval huggingface dataset:
A SIP-SHIM6-based solution providing interdomain service continuity in IMS-based networks (2012)

Nowadays, wireless networks are largely deployed, and the number of smart phones has boomed, as well as data transfer via mobile phones. This has resulted in the emergence of multihoming, which allows the user to enjoy the best access for each application. The context of our work is mobile multihomed terminals in a heterogeneous environment. We propose a solution for interdomain mobility management with end-to-end service continuity of communication. For this purpose, we combine a multihoming protocol (SHIM6), which ensures a seamless network change, with the IMS architecture, which allows the establishment of multimedia sessions with quality of service. Our proposal enables a mobile terminal to change its access network seamlessly, without any application disruption. To achieve this, we implement a P-SIP inside the terminal to manage the signaling procedures. The proposed scheme can manage the interdomain mobility of a terminal in two modes: reactive and proactive. A testbed allows us to show the feasibility of our approach and the obtained gain by reducing considerably the handover delay and thus, the data loss.
[Hemostatic potential during the development of post-mastectomy edema]. (1990)

The work deals with the study of the mosaic character of the hemostatic potential, connected with the development of a localized pathological process, taking postmastectomy edema in illustration. It is shown that this condition is an example of the manifestation of the RASK system mosaics in one organism in pathology. It should be pointed out that the degree of the development of the local DVS syndrome changes significantly some of the RASK system parameters at the level of the whole organism. This is evidence that normalization of the microcirculatory processes in the edematous extremity will be an important measure in complex treatment of postmastectomy edema. It will considerably lower the risk of general disorders of the RASK system. Parameters determined in the blood collected from the extremity on the side of the operation will serve as controls of the efficacy of the applied therapeutic measures.
New reflow process for indium bump (1997)

A new reflow method for indium bump of hybridized HgCdTe IRFPA is proposed using H<SUB>2</SUB> plasma. Twenty micrometer height indium bump is easily achieved with this method. In the new method, H<SUB>2</SUB> plasma makes the indium bump surface clean with removing the oxidized indium by H radical chemical reaction. Simultaneously, H<SUB>2</SUB> plasma increases the temperature of indium bump above 160 degrees Celsius. This sphere shaped bump is easily deformed plastically with relatively small force. Force of 2 g/bump changes the 20 micrometer height bump to 10 micrometer. The flip-chip bonding technique using the new reflow method is characterized with shear strain strength measurement. It is found that bonding reliability can be improved owing to increased height and smooth surface.
Simple Scaling Law for Rotational-Energy Transfer inNa2*-Xe Collisions (1978)

We have measured the thermally averaged rate constants for rotationally inelastic collisions of ${\mathrm{Na}}_{2}$* and Xe for six values of initial angular momentum ${j}_{0}$ and for changes in $j$ up to 30. We propose a new scaling law which fits all these rates within 20%. This scaling law implies that ${m}_{j}$ is conserved in the collision, and shows that the square of the $T$ matrix has a power-law dependence on the energy transferred. These results suggest the importance of dynamical effects in rotationally inelastic collisions.
A Comparative Study of the Processing and Properties of Natural and Synthetic Polyisoprene Rubber Latex (1970)

Abstract A comparison of natural polyisoprene latex with that of synthetic polyisoprene latex included latex properties, raw latex films, compound stability and processing, prevulcanization, vulcanizate properties, foam rubber, dipping, and adhesives. A number of differences were seen between the two latexes. It is obvious that synthetic polyisoprene latex is a very different latex to its natural counterpart. In many properties in the wet and dry state, raw or vulcanized, the synthetic latex shows inferior properties to that of natural latex. The unique combination of the polyisoprene rubber phase and the stabilizing system of protein/fatty acid soap in natural rubber latex concentrate make it superior in processing and properties to the synthetic polyisoprene latex. Many of the published claims for the synthetic material failed to receive experimental support in this study.
Engineering CRISPR/Cas9 to mitigate abundant host contamination for 16S rRNA gene-based amplicon sequencing (2020)

Our Cas-16S-seq can efficiently remove abundant host contamination without a bias for 16S rRNA gene-based amplicon sequencing, thereby enabling deeper bacterial community profiling with a low cost and high flexibility. Thus, we anticipate that this method would be a useful tool for plant microbiomics. Video Abstract.
TMEM16A Protein: A New Identity for Ca2+-Dependent Cl− Channels (2010)

Ca(+)-dependent Cl⁻ channels (CaCCs) play a variety of physiological roles in different organs and tissues, including transepithelial Cl⁻ secretion, smooth muscle contraction, regulation of neuronal excitability, and transduction of sensory stimuli. The recent identification of TMEM16A protein as an important component of CaCCs should allow a better understanding of their physiological role, structure-function relationship, and regulatory mechanisms.
The rotation of mouse myoblast nuclei is dependent on substrate elasticity (2017)

The complex interplay of biochemical signaling and mechanical traction forces regulate the position of cellular nuclei. Although the phenomenon of nuclear rotation has been observed for many years, the influence of substrate elasticity was unknown. We discovered another layer of complexity to this phenomenon: nuclear rotation is dependent on substrate elasticity. Nuclear rotation is drastically reduced on physiologically relevant stiffnesses. Here, we studied nuclear rotation in mouse C2C12 myoblasts cultured on soft substrates designed to mimic resting tissue (∼26 kPa) and on hard glass substrates. We examined the roles of the actin and microtubule cytoskeleton on the presence and dynamics of nuclear rotation in these two different microenvironments. We demonstrated the clear dependence of nuclear rotation dynamics on matrix stiffness. These results will have important implications for the design of future studies of nuclear rotation and our understanding of the phenomenon as a whole. Unnaturally, hard substrates do not only fail to mimic the in vivo microenvironment, but can also induce cellular processes that would not normally occur in the natural cellular environment.
Plant-Pathogen Interactions in Plant Biotechnology (1999)

Pl a n t s can interact with a diversity of micro-organisms with both detri­mental and beneficial outcomes. Many pathogenic microbial infections result in plant disease, but often the plant is able to recognize and resist the attack by limiting its spread. Plant diseases cause enormous and often dev­ astating losses for agriculture and human nutrition. The damage occurs when pathogenic microbes overcome the plant’s defenses.
Red Sm:KGd(WO4)2 laser at 649 nm (2023)

We report on the first laser operation of a Sm<sup>3+</sup>-doped monoclinic KGd(WO<sub>4</sub>)<sub>2</sub> double tungstate crystal in the red spectral range. Pumped by a frequency-doubled optically pumped semiconductor laser (2ω-OPSL) at 479.1 nm, the 0.8 at. % Sm:KGd(WO<sub>4</sub>)<sub>2</sub> laser generated an output power up to 17.6 mW at 649.1 nm (the <sup>4</sup>G<sub>5/2</sub> → <sup>6</sup>H<sub>9/2</sub> transition) with a slope efficiency of 16.9%, a laser threshold down to 29 mW and a linear polarization. The laser exhibited a self-pulsing behavior, delivering µs-long pulses with a repetition rate of a few kHz. The polarized spectroscopic properties of Sm<sup>3+</sup> ions were determined as well.
Sharing in God�s surprise: The place and role of the Department of Science of Religion and Missiology at the University of Pretoria (2009)

During the centenary year of the University of Pretoria (2008), the Department of Science of Religion and Missiology took stock of its activities during the past 55 years, since the first professor in Missiology, H.D.A. du Toit, was appointed. In his wake a number of missiologists followed � C.W.H. Boshoff, D. Crafford, P.G.J. Meiring, J.J. Kritzinger, P.J. van der Merwe, A.S. van Niekerk and C.J.P. Niemandt � each of whom has contributed to the formation of hundreds of ministers and missionaries, as well as to the development of missiology and science of religion in South Africa through their research and writings. In this article, the place of missiology among the other theological disciplines at the University of Pretoria is discussed, together with an analysis of the nature and the mandate of missiology and science of religion in South Africa in our day. This article discusses five specific challenges to missiology at the beginning of the third millennium, namely to maintain its theological �roots�; to operate in close relationship with the church; to focus on our African context; to concentrate on a relevant agenda; and to develop a responsible methodology. Attention is given to some of the more important publications by members of the Department.
ChemInform Abstract: THERMAL DEOXYGENATION OF SYN‐15,16‐DIOXO‐1,6:8,13‐BISMETHANO(14)ANNULENE TO THE PYRENE ISOMER AZULENO(2,1,8‐IJA)AZULENE (DICYCLOHEPTA(CD,GH)PENTALENE) (1985)

Abstract Aus dem Dion (I), das thermisch bis 500°C stabil ist, entstehen bei der Strömungsthermolyse zwischen 500 und 600°C das Azuleno‐azulen (II) und Anthracen (III).
Electrical properties of back-gated n -layer graphene films (2007)

We present results of room temperature studies of the electrical characteristics of back-gated ultrathin graphite films prepared by mechanical transfer of thin sections of Highly Oriented Pyrolytic Graphite (HOPG) to a Si/SiO<sub>2</sub> substrate. The films studied were quite thin, exhibiting only a few graphene layers (<i>n</i>). Films with thickness in the range 1 < <i>n</i> < 20 were studied, where <i>n</i> has been deduced by Atomic Force Microscopy (AFM) z-scans. The <i>n</i> value deduced by AFM z-scan data was correlated with the <i>n</i> value deduced by Raman scattering data. We discuss at some length, the issue of whether or not Raman scattering can provide a standalone measure of n<i></i>. Electrical contacts were made to a few of the low <i>n</i> (<i>n</i> = 1,2,3) graphene films. Most graphene films exhibited a nearly symmetric resistance (R) anomaly vs. gate voltage <i>(V<sub>G</sub>)</i> in the range 25 <i>< V<sub>G</sub></i> < 110 V; some films exhibited as much as a factor of ~50 decrease in <i>R</i> (relative to the maximum R) with changing VG. An interesting low bias shoulder on the negative side of the resistance peak anomaly was also observed. The devices were fabricated with a lithography free process.
SUN-333 Expression of Type 2 Somatostatin Receptors and Low Tumor Markers of Aggressiveness Correlate with Positive 68Ga-DOTATATE Findings in Ectopic ACTH-Producing Tumors (2019)

Background: Ectopic ACTH Syndrome (EAS) is caused by over production of ACTH from non-pituitary neuroendocrine tumors (NET). Tumor localization is challenging; lesions are often < 1 cm in diameter or slow growing so that they are not seen on thin-cut CT or FDG-PET. The use of functional imaging such as 68Ga-DOTATATE PET/CT (DOTATATE) and 6 mCi Octreoscan (OCT) takes advantage of somatostatin receptor expression on these NETs [1-3]. Here, we studied the type 2 somatostatin receptor (SSTR2) expression in ectopic ACTH-producing tumors by immunohistochemistry (IHC) and correlated it with DOTATATE and OCT findings. Methods: All 17 patients (pts) had anatomic and functional imaging and histologic confirmation of EAS. IHC of tumors included evaluation of ACTH, SSTR2 and Ki67; pancreatic tissue islets were the positive SSTR2 control. An experienced research pathologist scored positive staining by the distribution of staining throughout the tumor (diffuse or patchy/focal), the % of cells that were positive (as 1 – 30%, >30-<60% or >60%), and staining intensity (as 1-3). We correlated the IHC findings with imaging (positive or negative in tumor site) and aggressiveness markers in the area of greatest IHC staining, defined as the Ki67 index (<3%, >3-20%, or >20% positive), mitotic count in 10-25 high power fields (HPF), or presence of tumor necrosis or metastasis. Results: The median age at diagnosis was 50 ± 12 years, 65% were females (n:11/17), median tumor size 9 mm (range 4-67 mm). Tumor was identified by DOTATATE in 13/16 pts and by OCT in 3/17. All 17 resected tumors stained for ACTH. Tumor type and location included 11 pulmonary NETs (64%), and 1 each of pulmonary tumorlets, appendiceal NET, ovarian teratoma, mediastinal NET, pheocromocytoma and a NET in a lymph node with unknown primary. Ten tumors had 3+ SSTR2 staining in >75% cells; DOTATATE was positive for all, OCT detected only 3. Four tumors had 0 – 1% of SSTR2 positive cells; DOTATATE was positive in 2 and OCT in none. Three tumors had <10, <25 and 50% staining and 1-2+ intensity; DOTATATE detected 1 and OCT none. Both scans were negative in a mediastinal NET with necrosis, Ki67 >20%, 25 mitoses/10 HPF and <1% SSTR2+ cells, and a metastatic ovarian teratoma with Ki67 21%, mitotic count 21/10HPF and <25% SSTR2+ cells. Conclusions: Most EAS tumors in our cohort were small, expressed SSTR2, and lacked markers of aggressiveness. Strong SSTR2 expression correlated with positive 68Ga-DOTATATE findings in 100% of cases but only 33% of OCT cases. Negative or limited SSTR2 receptor distribution was associated with 43% rate of DOTATATE positivity. Further investigation is needed into expression of other SSTRs to understand this finding. We speculate that positive imaging is a complex reflection of tumor size, SSTR expression, and malignancy potential.
Simultaneous bidirectional pam-6 wired link with adaptive pre-emphasis and trellis coding (2005)

This work presents a novel design for a simultaneous bidirectional multilevel wireline transmission system with adaptive pre-emphasis and trellis coded modulation. The incorporation of a trellis encoder and a Viterbi decoder provides coding gain to offset the loss of SNR caused by the multilevel pulse amplitude modulation. Furthermore, the feedback loop inherent in a simultaneous bidirectional link provides a natural opportunity to use adaptive pre-emphasis to compensate for channel characteristics. Our simulation results demonstrate the effectiveness of this approach.
CURRENT SURGICAL TECHNIQUES: Surgery for hyperparathyroidism (1996)

Management of parathyroid disease remains primarily surgical. In experienced hands, cure rates of 95% to 98% for primary hyperparathyroidism can be expected. Knowledge of embryology and experience with the pertinent anatomy is of paramount importance in achieving a consistently high success rate. Preoperative localization and the extent of surgery (unilateral vs bilateral) are the main areas of controversy. New developments include a rapid bioassay that allows for intraoperative determination of parathyroid hormone levels. This procedure may help the surgeon determine when the hyperactive gland has been removed. Although localization studies are imperative in secondary procedures, their role in primary exploration is controversial. If one is willing to consider a unilateral exploration as adequate, then preoperative studies will contribute to the success of that procedure. The the cost-benefit ratio, however, has not been proven to be favorable. Ultimately, surgical preference and expertise determine the treatment options.
LED as transmitter and receiver in POF - based bidirectional communication systems (2018)

Light emitting diodes (LED) can be used not only as light sources but also as light detectors similar to photodiodes. This property will here be used to extend a commercial plastic optical fiber (POF) based one directional communication system to a bidirectional communication system with the possibility to work in half duplex mode. It will be shown that this approach can generally simplify essentially the optical setup of bidirectional optical communication systems. Furthermore, the transmission of light energy via POF will be utilized to provide a node in an optical communication system with electrical energy. Such power over optical fiber system makes a node in the communication system independent of the access to external electrical power supply. The system performance will be discussed in dependence of the electro optical properties of POF based communication systems.
Mathematical background (2005)

Correlation filter theory relies heavily on concepts and tools from the fields of linear algebra and probability theory. Matrices and vectors provide succinct ways of expressing operations on discrete (i.e., pixelated) images, manipulating multiple variables and optimizing criteria that depend on multiple parameters. A vector representation also facilitates parallel operations on a set of constants or variables. Thus linear algebra provides powerful tools for digitally synthesizing and analyzing correlation filters.
miR-221-3p Regulates VEGFR2 Expression in High-Risk Prostate Cancer and Represents an Escape Mechanism from Sunitinib In Vitro (2020)

Downregulation of miR-221-3p expression in prostate cancer (PCa) predicted overall and cancer-specific survival of high-risk PCa patients. Apart from PCa, miR-221-3p expression levels predicted a response to tyrosine kinase inhibitors (TKI) in clear cell renal cell carcinoma (ccRCC) patients. Since this role of miR-221-3p was explained with a specific targeting of VEGFR2, we examined whether miR-221-3p regulated VEGFR2 in PCa. First, we confirmed VEGFR2/KDR as a target gene of miR-221-3p in PCa cells by applying Luciferase reporter assays and Western blotting experiments. Although VEGFR2 was mainly downregulated in the PCa cohort of the TCGA (The Cancer Genome Atlas) database, VEGFR2 was upregulated in our high-risk PCa cohort (<i>n</i> = 142) and predicted clinical progression. In vitro miR-221-3p acted as an escape mechanism from TKI in PC3 cells, as displayed by proliferation and apoptosis assays. Moreover, we confirmed that Sunitinib induced an interferon-related gene signature in PC3 cells by analyzing external microarray data and by demonstrating a significant upregulation of miR-221-3p/miR-222-3p after Sunitinib exposure. Our findings bear a clinical perspective for high-risk PCa patients with low miR-221-3p levels since this could predict a favorable TKI response. Apart from this therapeutic niche, we identified a partially oncogenic function of miR-221-3p as an escape mechanism from VEGFR2 inhibition.
Matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometric imaging of synthetic polymer sample spots prepared using ionic liquid matrices (2014)

Ionic liquid matrices can be used to overcome segregation, a typical drawback of conventional MALDI dried-droplet preparations. Homogeneous sample spots are easy to prepare, stable in the MS vacuum and, thereby, improve the reproducibility of MALDI.
COMPUTER SIMULATION METHOD FOR CRACK GROWTH USING INTERFACE ELEMENT EMPLOYING LENNARD-JONES TYPE POTENTIAL FUNCTION (1999)

The phenomena of crack propagation and interface debonding can be regarded as formation of new surface. Thus, it is quite natural to model these problems by introducing the mechanism of surface formation. The authors proposed a method in which the formation of new surface is represented by interface element based on the interface potential energy. The general idea of the interface element and its application to peeling test of bonded plates, push-out test of fiber in matrix, dynamic crack propagation and ductile tearing of steel plate are presented.
Review of Recent Eduinformatics Research (2019)

In 2018, we introduced “Eduinformatics,” a new field of education that combined both education and informatics. This article reviews recent eduinformatics research and considers the status and direction of future work in this particular field of education.
Self-Healing Cloud Services in Private Multi-Clouds (2018)

As clouds continue to dominate as the de facto means of consuming shared computing resources, cloud providers are required to ensure that their services always meet or exceed service level agreements in terms of availability, reliability, scalability, performance etc every hour, day and year. These challenging requirements are even exacerbated when it comes to multi-cloud environments. In the era of automation and continuous cost reductions, using humans to manually test and trigger corrective actions when needed in order to fulfill these service level agreements is considered cumbersome and too expensive. In order to thrive, cloud service providers need a solution which is efficient, cheaper to deploy and easy to operate. This paper introduces a distributed container based solution for testing and self-healing of cloud resources. The proposed solution is based on a containerized multi-agent architecture which leverages Elasticsearch, Logstash, Kibana (ELK) stack and uses a rule-based self-healing algorithm implemented using Drools rule engine and Spring Boot framework. Preliminary tests show that the solution meets its target objectives in terms of maintaining service level agreements, lowering deployment costs, high performance and operability.
Alcohol's impact upon glycobiology. (1997)

This report reviews and illustrates ways in which some of the problems linked to excessive alcohol intake may develop from alcohol-induced alterations of eukaryotic cell surface molecules. Alcohol is the number one drug of abuse in the US, affecting at least 15 million Americans and causing annual losses of more than $80 billion and 100,000 lives. An estimated 20-40% of all persons admitted to general hospitals have alcohol-related problems and are often undiagnosed alcoholics being treated for the consequences of their drinking. Chronic alcohol-related cirrhosis of the liver is the ninth leading cause of death in the US, with over 28,000 deaths annually. Alcohol has harmful effects on almost every organ system in the body, producing cardiovascular disorders, liver disease, neuropathological illness and fetal injury. The etiologic mechanisms for these effects of alcohol is a research area of considerable importance to the National Institute for Alcohol Abuse and Alcoholism.
Capacity Enhancement for Irregular Reconfigurable Intelligent Surface-Aided Wireless Communications (2020)

Reconfigurable intelligent surface (RIS) is an emerging technology to improve the spectral efficiency of wireless communication systems. However, the increase of RIS elements results in the non-negligible overhead of channel estimation and channel feedback, as well as the high complexity of beam design. Therefore, how to improve the system capacity with a limited number of RIS elements becomes a challenge. In this paper, we propose a brand new irregular RIS structure to enhance the capacity of RIS-aided wireless communications. The key idea is to irregularly configure a given number of RIS elements on an enlarged surface, which provides extra degrees of freedom and spatial diversity compared with the classical regular RIS. For the proposed irregular RIS-aided communication, we then formulate the joint topology and beamforming design problem to maximize the system capacity. Accordingly, we propose a joint optimization framework with low complexity to alternately optimize the RIS topology and the corresponding beamforming design. Finally, simulation results demonstrate that the proposed irregular RIS with a limited number of RIS elements can significantly enhance the system capacity compared with the traditional regular RIS.