gebhart/patrepeval huggingface dataset:
Reactions of Olefin Polymerization Activators with Complexed Pentamethylcyclopentadienyl Ligands:  Abstraction of Tetramethylfulvalene (1998)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTReactions of Olefin Polymerization Activators with Complexed Pentamethylcyclopentadienyl Ligands: Abstraction of TetramethylfulvaleneWilliam J. Evans, Kevin J. Forrestal, Mohammad A. Ansari, and Joseph W. ZillerView Author Information Department of Chemistry University of California, Irvine Irvine, California 92697-2025 Cite this: J. Am. Chem. Soc. 1998, 120, 9, 2180–2181Publication Date (Web):February 20, 1998Publication History Received2 September 1997Published online20 February 1998Published inissue 1 March 1998https://pubs.acs.org/doi/10.1021/ja973058vhttps://doi.org/10.1021/ja973058vrapid-communicationACS PublicationsCopyright © 1998 American Chemical SocietyRequest reuse permissionsArticle Views315Altmetric-Citations39LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information SUBJECTS:Alkyls,Hydrocarbons,Lewis acids,Ligands,Olefin polymerization Get e-Alerts
The role of Raf-1 in radiation resistance of human hepatocellular carcinoma Hep G2 cells (2004)

Development of radiation resistance is one of the major reasons that cancer cells do not respond to radiotherapy and the mechanism for resistance is still not clear. Two sublines of human hepatocellular carcinoma Hep G2 cells were established from cells that survived two different irradiation regimes, 2 Gy for 10 days or 10 Gy for 2 days, respectively. Using MTT assay, the radiation conditioned cells were found to be more resistant to gamma-irradiation and have a greater extent of potentially lethal damage repair (PLDR) for radiation than the parent cells. By Western blot analysis, the radiation-conditioned cells were found to overexpress Raf-1 which is known to regulate the radiation resistance of cells. Inhibition of Raf-1 expression by antisense oligonucleotides increased the radiation sensitivity of the radiation-conditioned cells while inhibitors of Ras (L744,832), PI3K (LY294002) and p38 (SB203580) had no effect. Moreover, antisense Raf-1 oligonucleotides also decreased the radiation induced PLDR capacity of the radiation conditioned cells. It is therefore suggested that Raf-1 may induce radiation resistance through an increase in radiation induced PLDR capacity in Hep G2 cells.
Static and Dynamic Mechanical Behavior of Hydroxyapatite-Polyacrylic Acid Composites Under Simulated Body Fluid (2006)

In this work, we have investigated mechanical response of hydroxyapatite/polyacrylic composites under dry, wet and simulated body fluid conditions. Hydroxyapatite (HAP) is mineralized under two conditions; one, in presence of polyacrylic acid (in situ HAP), second, in absence of polyacrylic acid (ex situ HAP). Further, in situ and ex situ HAP are mixed with polyacrylic acid to make HAP/PAAc composites. Interfacial interactions between PAAc and HAP have been studied using photoacoustic Fourier transform infrared spectroscopy (PAS-FTIR). The mechanical response of the composites under wet condition is studied by soaking composite samples in simulated body fluid (SBF). Under wet conditions, SBF and water weaken the HAP-HAP interface significantly. PAS-FTIR data suggests that PAAc attaches to HAP through the dissociated carboxylate groups. The water and SBF soaked samples showed creep-like behavior and exhibit large residual strain after unloading. Loading under different strain rates has significant effect on mechanical properties of these composites. Both in situ and ex situ 70:30 composites exhibit highest elastic modulus at strain rate of 0.01 sec-1. XRD study indicates formation of Ca2P2O7 phase in ex situ composite after soaking in SBF and water for 3 hours, whereas in situ composites showed presence of only hydroxyapatite phase after soaking in SBF and water for same duration of time.
Robot pose estimation in unknown environments by matching 2D range scans (1994)

We develop two algorithms to register a range scan to a previous scan so as to compute relative robot positions in an unknown environment. The first algorithm is used on matching tangent lines defined on two scans and minimizing a distance function. The second algorithm iteratively establishes correspondences between points in the two scans and then solves the point-to-point least-squares problem to compute the relative pose. Our methods avoid the use of localized features. They work in curved environments and can handle partial occlusions.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Endoscopic ligation of oesophageal varices compared with injection sclerotherapy in primary biliary cirrhosis (2000)

EVL significantly reduced the adverse effects associated with EIS at the initial session in primary biliary cirrhotic patients.
Neutralization of cholera toxin with nanoparticle decoys for treatment of cholera (2018)

Diarrheal diseases are a major cause of morbidity and mortality worldwide. In many cases, antibiotic therapy is either ineffective or not recommended due to concerns about emergence of resistance. The pathogenesis of several of the most prevalent infections, including cholera and enteroxigenic Escherichia coli, is dominated by enterotoxins produced by lumen-dwelling pathogens before clearance by intestinal defenses. Toxins gain access to the host through critical host receptors, making these receptors attractive targets for alternative antimicrobial strategies that do not rely on conventional antibiotics. Here, we developed a new nanotechnology strategy as a countermeasure against cholera, one of the most important and prevalent toxin-mediated enteric infections. The key host receptor for cholera toxin, monosialotetrahexosylganglioside (GM1), was coated onto the surface of polymeric nanoparticles. The resulting GM1-polymer hybrid nanoparticles were shown to function as toxin decoys by selectively and stably binding cholera toxin, and neutralizing its actions on epithelial cells in vitro and in vivo. Furthermore, the GM1-coated nanoparticle decoys attenuated epithelial 3',5'-cyclic adenosine monophosphate production and fluid responses to infection with live Vibrio cholera in cell culture and a murine infection model. Together, these studies illustrate that the new nanotechnology-based platform can be employed as a non-traditional antimicrobial strategy for the management of enteric infections with enterotoxin-producing pathogens.
Virus Adaptation and Selection Following Challenge of Animals Vaccinated against Classical Swine Fever Virus (2019)

Vaccines against classical swine fever have proven very effective in protecting pigs from this deadly disease. However, little is known about how vaccination impacts the selective pressures acting on the classical swine fever virus (CSFV). Here we use high-throughput sequencing of viral genomes to investigate evolutionary changes in virus populations following the challenge of naïve and vaccinated pigs with the highly virulent CSFV strain "Koslov". The challenge inoculum contained an ensemble of closely related viral sequences, with three major haplotypes being present, termed A, B, and C. After the challenge, the viral haplotype A was preferentially located within the tonsils of naïve animals but was highly prevalent in the sera of all vaccinated animals. We find that the viral population structure in naïve pigs after infection is very similar to that in the original inoculum. In contrast, the viral population in vaccinated pigs, which only underwent transient low-level viremia, displayed several distinct changes including the emergence of 16 unique non-synonymous single nucleotide polymorphisms (SNPs) that were not detectable in the challenge inoculum. Further analysis showed a significant loss of heterogeneity and an increasing positive selection acting on the virus populations in the vaccinated pigs. We conclude that vaccination imposes a strong selective pressure on viruses that subsequently replicate within the vaccinated animal.
Supplementary methods from Activating Mutations in <i>Pik3ca</i> Contribute to Anal Carcinogenesis in the Presence or Absence of HPV-16 Oncogenes (2023)

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Biological effects of 2-oxoglutarate with particular emphasis on the regulation of protein, mineral and lipid absorption/metabolism, muscle performance, kidney function, bone formation and cancerogenesis, all viewed from a healthy ageing perspective state of the art--review article. (2008)

The fact that men and women are living longer than they have ever done before is something in which we can all rejoice. However, the process of ageing is associated with changes in skeletal, muscular, gastrointestinal, neural hormonal and metabolic processes that seriously affect an individual's performance and quality of life. Indeed, such changes can be contributory to a loss of independence in the elderly. This state-of-the art address highlights the main changes found to occur with ageing whilst simultaneously reporting findings of in vivo and in vitro studies designed to elucidate the potential of the Krebs cycle intermediate - alpha-ketoglutaric acid (AKG) in protecting elderly body systems from failing and degradation. The topics of paramount importance include impaired bone structure and strength, amino acid and mineral absorption, muscle performance, as well as highlighting the role of Krebs cycle intermediates in the debilitating changes that occur with end-stage renal failure and the regulation of the lipid metabolism. Finally, focus will be given to the role of 2-oxoglutarate as a potent protective factor in connection with the development of malignant cells in the body.
Genetic Difference in Susceptibility and Fatality of Three Strains of Mice Experimentally Infected with Neodiplostomum seoulense (2000)

The genetic influence on host susceptibility to Neodiplos- tomum seoulense infection and fatality of the host was studied in 3 inbred strains of mice (BALB/c (H-2d), C3H/He (H-2k), and C57BL/6 (H-2b)). The survival of the mice, worm expulsion kinetics, worm size, number of eggs produced per day (EPD), and number of uterine eggs were observed from day 1 to day 40 postinfection (PI) with 100 or 200 metacercariae per mouse. Infection with N. seoulense was highly lethal to all 3 strains of mice, but the lethality was dose-dependent and varied according to the genetic backgrounds of the mice. The C3H/He mice exhibited the highest mortality, the lowest worm burdens and EPD, and the quickest expulsion of worms. It is suggested that different genetic backgrounds of mice appear to affect the host's capacity to expel N. seoulense and the fatality of the hosts themselves.
Rebound and overshoot of donor‐specific antibodies to human leukocyte antigens (HLA) during desensitization with plasma exchanges in hematopoietic progenitor cell transplantation: A case report (2021)

Unexpected and rapid increases of a DSA can occur despite the use of current desensitization approaches. This is problematic when conditioning has already started, as such increases are unlikely to be overcome by TPE or other interventions for desensitization. Overshoot of DSA in HPC transplantation has rarely been reported. Its cause remains unclear and can include underlying disease, immunotherapy, chemotherapy, or TPE.
Piezoelectric transformer-based DC/DC converter with improved burst-mode control (2013)

This paper proposed a new control strategy of piezoelectric transformer based DC-DC converter in burst-mode operation. Burst-mode control is adopted for achieving output voltage regulation and for enabling the converter to operate at constant switching frequency as well as to keep a good efficiency at light load conditions. However, in practice, the piezoelectric transformer (PT) cannot stop instantly to vibrate due to its high quality factor. The delay in the output voltage change, resulting from this behavior influences the accuracy of the regulation. This paper proposes a control strategy to make the piezoelectric transformer can stop more quickly so as to enhance the accuracy of burst-mode control. The proposed method only modifies the control signal of the burst-mode driving circuit.
ICS teaching module: Ambulatory urodynamic monitoring (2015)

The clinical role of AUM is still controversial. The scientific evidence on the usefulness of AUM is still limited but the ICS Urodynamics Committee recommends its use as a second line diagnostic tool when office laboratory urodynamics have failed to achieve a diagnosis. AUM has been showed to be more sensitive than laboratory urodynamics in diagnosing detrusor overactivity but the level of evidence for this measurement is not high. This manuscript summarizes the evidence and provides practice recommendations on AUM for teaching purposes in the framework of an ICS teaching module. Neurourol. Urodynam. 36:364-367, 2017. © 2015 Wiley Periodicals, Inc.
Prostate Cancer Awareness Week, 1992: a summary of key findings. (1993)

Prostate Cancer Awareness Week was begun in 1989 to investigate whether men could be recruited to participate in free prostate cancer screening. Initially designed to raise public awareness of "the ignored male disease", it has become the largest single cancer screening program in the United States. In 1992, more than 500,000 men were examined by digital rectal examination (DRE) and more than half of these also by measuring prostate-specific antigen (PSA). Although the populations examined have been generally better educated than the national average, predominantly white, and typically (> 40%) experiencing some symptom of prostate disease, adherence to annual prostate examinations remains low among successive cohorts of participants. Prostate cancers detected through this program exhibit a more favorable stage distribution than the national average. From 1989 through 1992, many cancers were detected by using the effective combination of DRE and PSA testing, which resulted in more stage A disease being diagnosed and fewer stage B, C, and D tumors. Data from 1992 suggest that increasing sophistication is possible with PSA test results, and age-specific PSA reference ranges have been developed.
El misterio del capital. Por qué el capitalismo triunfa en Occidente y fracasa en el resto del mundo (2016)

En “El misterio del capital” De Soto argumenta que la base del capitalismo, de la generacion de riqueza y de la reduccion de la pobreza se encuentra en el reconocimiento y la adecuada proteccion de los derechos de propiedad. La obra se escribio con el trasfondo de la desintegracion de la URSS y el proceso descolonizador, aunque ha recobrado vigencia con la crisis financiera de 2008 y sus secuelas. En este articulo se repasan los principales argumentos de esta obra.
Energy Harvester with a Dynamic Magnifier (2011)

Conventional energy harvester typically consists of a piezoelectric element, which is sandwiched between a proof mass and a base subjected to sinusoidal excitation. The resulting relative motion between the proof mass and the base produces a mechanical strain in the piezoelectric element, which is converted into electrical power by virtue of the direct piezoelectric effect. In this study, harvester is provided with a dynamic magnifier consisting of a spring-mass system which is placed between the piezoelectric element and the moving base. The main function of the dynamic magnifier, as the name implies, is to magnify the strain experienced by the piezo-element in order to amplify the electrical power output of the harvester. With proper selection of the design parameters of the magnifier, the harvested power can be dramatically enhanced and the effective bandwidth of the harvester can be improved. The theory governing the operation of this class of energy harvesters with dynamic magnifier (EHDM) is developed using the Lagrangian dynamics approach. Numerical examples are presented to illustrate the performance characteristics of the EHDM in comparison with the conventional energy harvesters. The obtained results demonstrate the feasibility of the EHDM as a simple and effective means for enhancing the magnitude and spectral characteristics of conventional harvesters.
Intercarrier interference in MIMO OFDM (2003)

We examine multicarrier transmission over time-varying channels. We first develop the model for such a transmission scheme and focus particularly on OFDM-based schemes. We analyze the impact of time-variation within a transmission block which could arise both from Doppler spread of the channel and from synchronization errors. We propose a time-domain approach to mitigate the effects of such time-variations. This approach reduces to the familiar single-tap frequency-domain equalizer when the channel is block time-invariant. We also develop this in the context of multiple transmit and receive antennas and specialize the receiver to space-time block-coded systems. Finally we provide numerical results.
Error correction for Moiré based creep measurement system (2014)

Due to the high temperatures and stresses present in the high-pressure section of a gas turbine, the airfoils experience creep or radial stretching. Nowadays manufacturers are putting in place condition-based maintenance programs in which the condition of individual components is assessed to determine their remaining lives. To accurately track this creep effect and predict the impact on part life, the ability to accurately assess creep has become an important engineering challenge. One approach for measuring creep is using moiré imaging. Using pad-print technology, a grating pattern can be directly printed on a turbine bucket, and it compares against a reference pattern built in the creep measurement system to create moiré interference pattern. The authors assembled a creep measurement prototype for this application. By measuring the frequency change of the moiré fringes, it is then possible to determine the local creep distribution. However, since the sensitivity requirement for the creep measurement is very stringent (0.1 micron), the measurement result can be easily offset due to optical system aberrations, tilts and magnification. In this paper, a mechanical specimen subjected to a tensile test to induce plastic deformation up to 4% in the gage was used to evaluate the system. The results show some offset compared to the readings from a strain gage and an extensometer. By using a new grating pattern with two subset patterns, it was possible to correct these offset errors.
The role of kinetic instabilities in formation of the runaway electron current after argon injection in DIII-D (2018)

Here, kinetic instabilities in the MHz range driven by runaway electrons (REs) have been observed for the rst time during the current quench in disruptions triggered by massive injection of argon in DIII-D. These instabilities are well-correlated with intermittent RE losses in the beginning of runaway electron current formation. The runaway current phase is not observed when the power of instabilities exceeds a threshold. Novel measurements of the RE distribution function during the current quench indicate that the instabilities appear when RE energy (<em>E</em><sub>RE</sub>) exceeds 2.5{3 MeV, the number of modes grows linearly with <em>E</em><sub>RE</sub>, and their frequencies lie in the range 0.1–3 MHz, below the ion cyclotron frequency. Possible plasma waves exciting by REs in this region are proposed. Increase of the amount of injected argon decreases the <em>E</em><sub>RE</sub> and increases the success rate of the runaway current formation, while increase of the pre-disruption plasma current acts in the opposite direction. No dependence on the pre-disruption core electron temperature is found.
Instrument response measurements of ion mobility spectrometers in situ: maintaining optimal system performance of fielded systems (2005)

Ion Mobility Spectroscopy (IMS) is the most widespread detection technique in use by the military for the detection of chemical warfare agents, explosives, and other threat agents. Moreover, its role in homeland security and force protection has expanded due, in part, to its good sensitivity, low power, lightweight, and reasonable cost. With the increased use of IMS systems as continuous monitors, it becomes necessary to develop tools and methodologies to ensure optimal performance over a wide range of conditions and extended periods of time. Namely, instrument calibration is needed to ensure proper sensitivity and to correct for matrix or environmental effects. We have developed methodologies to deal with the semi-quantitative nature of IMS and allow us to generate response curves that allow a gauge of instrument performance and maintenance requirements. This instrumentation communicates to the IMS systems via a software interface that was developed in-house. The software measures system response, logs information to a database, and generates the response curves. This paper will discuss the instrumentation, software, data collected, and initial results from fielded systems.
Investigating the oxidation mechanism of tantalum nanoparticles at high heating rates (2017)

Reduced diffusion length scales and increased specific surface areas of nanosized metal fuels have recently demonstrated increased reaction rates for these systems, increasing their relevance in a wide variety of applications. The most commonly employed metal fuel, aluminum, tends to oxidize rapidly near its melting point (660 °C) in addition to undergoing a phase change of the nascent oxide shell. To further expand on the understanding of nanosized metal fuel oxidation, tantalum nanoparticles were studied due to their high melting point (3017 °C) in comparison to aluminum. Both traditional slow heating rate and in-situ high heating rate techniques were used to probe the oxidation of tantalum nanoparticles in oxygen containing environments in addition to nanothermite mixtures. When oxidized by gas phase oxygen, the oxide shell of the tantalum nanoparticles rapidly crystallized creating cracks that may attribute to enhanced oxygen diffusion into the particle. In the case of tantalum based nanothermites, oxide shell crystallization was shown to induce reactive sintering with the metal oxide resulting in a narrow range of ignition temperatures independent of the metal oxide used. The oxidation mechanism was modeled using the Deal-Grove model to extract rate parameters, and theoretical burn times for tantalum based nanocomposites were calculated.
Measurement of the J/{Psi} elastic photoproduction from 100 GeV to 400 GeV in the experiment E687 at Fermilab (1990)

In the present paper we give the experimental measurement of the cross section per nucleon for the elastic J/{psi} photoproduction in six energy intervals from 100 GeV to 450 GeV; the overall d{sigma}/dt differential cross section, as well as an estimate of the coherent diffractive photoproduction off the Be nucleus. We will finally compare the energy dependence of our measured cross sections with the predictions of the PGF Model.