gebhart/patrepeval huggingface dataset:
Clinical applications of antineutrophil cytoplasmic antibody testing (2003)

Recent findings demonstrate that the combined use of indirect immunofluorescence tests and solid phase assays to detect antineutrophil cytoplasmic antibody directed against myeloperoxidase and proteinase 3 can minimize the occurrence of false-positive antineutrophil cytoplasmic antibody results. Furthermore, the yield of antineutrophil cytoplasmic antibody testing can be improved by the use of a well-standardized test, adherence to published guidelines, and restricting the use of the tests to clinical situations with a rather high pretest probability for antineutrophil cytoplasmic antibody-associated vasculitides. However, treatment decisions should be based on the clinical presentation of the patient and histologic findings and not on the results of antineutrophil cytoplasmic antibody testing alone.
Segregation and Exchange Properties of Alkylammonium Ions in a Smectite and Vermiculite (1973)

Abstract X-ray diffraction analysis of mixed alkylammonium-exchanged smectite revealed segregation of different ion species into randomly ordered layers. Vermiculite, however, showed segregation into crystallites, a behavior attributed to clay inhomogeneity. Ion segregation is explained by the hydration properties of cations as well as the energy requirements of layer expansion. Quaternary ammonium ions of different size were used to exchange ethylammonium-clays, and the effectiveness, as well as steric hindrance, of cation size in ion exchange was demonstrated. Layer charge density was related to the degree of ease of large cation adsorption. Basal spacing in suspension was found to be important in determining the preference of vermiculite for certain cations, while more freely-expanding, lower layer charge smectite did not demonstrate this phenomenon.
Crystal and molecular structures of the nickel and cobalt dichlorobis(diarsine)metal monochlorides (1972)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCrystal and molecular structures of the nickel and cobalt dichlorobis(diarsine)metal monochloridesPaula K. Bernstein, Gordon A. Rodley, Richard. Marsh, and Harry B. GrayCite this: Inorg. Chem. 1972, 11, 12, 3040–3043Publication Date (Print):December 1, 1972Publication History Published online1 May 2002Published inissue 1 December 1972https://pubs.acs.org/doi/10.1021/ic50118a033https://doi.org/10.1021/ic50118a033research-articleACS PublicationsRequest reuse permissionsArticle Views66Altmetric-Citations19LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
The CXCL16 A181V Mutation Selectively Inhibits Monocyte Adhesion to CXCR6 but Is Not Associated With Human Coronary Heart Disease (2011)

CXCL16-mediated cell adhesion plays at best a modest role in CHD, and the scavenging and chemotactic properties of the chemokine are more likely to be more important in disease pathogenesis.
Two-photon absorption and anisotropic transient energy transfer in BaTiO_3 with 1-psec excitation (1990)

We use a cross-polarized pump–probe technique and 1-psec pulses at 596 nm to measure a two-photon absorption coefficient of 0.1 cm/GW in BaTiO3. A long-lived absorption is also observed and is shown to be consistent with free-carrier absorption and charge redistribution between two separate impurity levels. We also observe an anisotropic transient energy-transfer process in which the p-polarized pump is scattered into the s-polarized probe. The energy transfer occurs when the c axis of the crystal is oriented along a grating vector equal to the difference between the pump- and probe-wave vectors.
Efficient stereo with multiple windowing (2002)

We present a new, efficient stereo algorithm addressing robust disparity estimation in the presence of occlusions. The algorithm is an adaptive, multi-window scheme using left-right consistency to compute disparity and its associated uncertainty. We demonstrate and discuss performances with both synthetic and real stereo pairs, and show how our results improve on those of closely related techniques for both robustness and efficiency.
Low-carbohydrate diets containing plant-derived fat but not animal-derived fat ameliorate heart failure (2023)

Cardiovascular disease (CVD) is a global health burden in the world. Although low-carbohydrate diets (LCDs) have beneficial effects on CVD risk, their preventive effects remain elusive. We investigated whether LCDs ameliorate heart failure (HF) using a murine model of pressure overload. LCD with plant-derived fat (LCD-P) ameliorated HF progression, whereas LCD with animal-derived fat (LCD-A) aggravated inflammation and cardiac dysfunction. In the hearts of LCD-P-fed mice but not LCD-A, fatty acid oxidation-related genes were highly expressed, and peroxisome proliferator-activated receptor α (PPARα), which regulates lipid metabolism and inflammation, was activated. Loss- and gain-of-function experiments indicated the critical roles of PPARα in preventing HF progression. Stearic acid, which was more abundant in the serum and heart of LCD-P-fed mice, activated PPARα in cultured cardiomyocytes. We highlight the importance of fat sources substituted for reduced carbohydrates in LCDs and suggest that the LCD-P-stearic acid-PPARα pathway as a therapeutic target for HF.
Neuropathic pain: a practical guide for the clinician (2006)

Neuropathic pain, caused by various central and peripheral nerve disorders, is especially problematic because of its severity, chronicity and resistance to simple analgesics. The condition affects 2%-3% of the population, is costly to the health care system and is personally devastating to the people who experience it. The diagnosis of neuropathic pain is based primarily on history (e.g., underlying disorder and distinct pain qualities) and the findings on physical examination (e.g., pattern of sensory disturbance); however, several tests may sometimes be helpful. Important pathophysiologic mechanisms include sodium-and calcium-channel upregulation, spinal hyperexcitability, descending facilitation and aberrant sympathetic-somatic nervous system interactions. Treatments are generally palliative and include conservative nonpharmacologic therapies, drugs and more invasive interventions (e.g., spinal cord stimulation). Individualizing treatment requires consideration of the functional impact of the neuropathic pain (e.g., depression, disability) as well as ongoing evaluation, patient education, reassurance and specialty referral. We propose a primary care algorithm for treatments with the most favourable risk-benefit profile, including topical lidocaine, gabapentin, pregabalin, tricyclic antidepressants, mixed serotonin-norepinephrine reuptake inhibitors, tramadol and opioids. The field of neuropathic pain research and treatment is in the early stages of development, with many unmet goals. In coming years, several advances are expected in the basic and clinical sciences of neuropathic pain, which will provide new and improved therapies for patients who continue to experience this disabling condition.
PRELIMINARY CLINICAL EVALUATION OF A Re-186 LABELED ANTI-CEA F(abʼ)2 ANTIBODY FRAGMENT AS A POTENTIAL RADIOIMMUNOTHERAPY AGENT. (1988)

Hanelin, L.; Schroff, R.; Fer, M.; Weiden, P.; Breitz, H.; Fisher, D.; Abrams, P.; Axworthy, D.; Ratliff, B.; Vanderheyden, J-L; Appelbaum, J.; Fritzberg, A. Author Information
Long‐term outcome in desbuquois dysplasia: A follow‐up in four adult patients (2003)

Desbuquois dysplasia is a rare chondrodysplasia characterized by short stature, joint laxity, and specific radiographic findings. We report the natural history of four patients (three boys and one girl) with Desbuquois dysplasia ages 16-22 years. The mean height in adulthood was 114 cm (-8.5 SD) with progressive deceleration of the growth curve from birth (-4 SD) to adulthood. Obesity was noted consistently and facial abnormalities were still present but less obvious than in childhood. Three of four patients had mental retardation of varying degree. Hyperlaxity was persistent but limited motion of various joints was also noted. Orthopedic complications included coxa vara or valga (3/4), scoliosis (3/4), marked lordosis (3/4), and ambulatory difficulties (3/4). Surgical treatment was necessary for all four patients, involving large joints, spine and hands. Other complications included acute open-angle glaucoma secondary to a congenital malformation of the angle in one case. In addition to consistent radiological findings, elevated greater trochanter, generalized osteoporosis especially of the spine, scoliosis and/or lordosis, wide metaphyses, flat epiphyses, and coxa vara or valga were part of the natural history of the disorder. Our study emphasizes the care of older patients with Desbuquois dysplasia.
Quality and Extent of Locum Tenens Coverage in Pediatric Surgical Practices (2015)

The prevalence and quality of locum tenens coverage in pediatric surgery have not been determined. An Internet-based survey of American Pediatric Surgical Association members was conducted: 1) practice description; 2) use and frequency of locum tenens coverage; 4) whether the surgeon provided such coverage; and 5) Likert scale responses (strongly disagree, disagree, neutral, agree, strongly agree) to statements addressing its acceptability and quality (two × five contingency table and χ(2) analyses, significance at P < 0.05). Three hundred sixteen of 1163 members (27.2% response rate) responded. One-fourth (24.1%) used a locum tenens regularly. Reasons were long-term inability to recruit a full-time surgeon (35.2%) and short-term vacancies (32.4%). One-fifth (20.4%) did locum tenens work; one-fourth (27.0%) plan to do so in the future. Two-thirds (64.2%) believe that surgical care in a locum tenens situation does not provide the same level of care as a full-time community-based surgeon. Most support locum tenens for short-term coverage (87.3%) and recruitment problems (72.1%), but not long-term vacancies (38.8%; P < 0.001) or permanent coverage (27.0%; P < 0.001). locum tenens coverage is an established feature of pediatric surgery. Most view it as a stopgap solution to the surgical workforce shortage.
Immunoassayable insulin in carcinoma of the cervix associated with hypoglycemia (1973)

Immunoassayable insulin was elevated in the plasma and in the primary and metastatic lesions of a patient with carcinoma of the cervix. The release of insulin from the tumor tissue could have been the important factor in precipitating acute episodes of hypoglycemia in this patient.
<title>Nonlinear optic in-situ diagnostics of a crystalline film in molecular-beam-epitaxy devices</title> (1991)

A new method of film structure in situ monitoring is proposed for MBE (molecular beam epitaxy) and MOCVD technologies. It is based on the analysis of second harmonic (SH) radiation induced in a growing film irradiated by a laser beam. SH intensity measurement versus angle of polarization plane of the incident light and versus film thickness provides the in situ information about film crystal quality, presence of polycrystal component, and crystallographic axes orientation. This method can be complementary to the well-known technique of fast electron diffraction (RHEED) and is supposed to be especially suitable for research groups since it allows a correlation between technological and crystallographic parameters to be quickly determined.© (1991) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Facial Expression Detection using Filtered Local Binary Pattern Features with ECOC Classifiers and Platt Scaling (2010)

We outline a design for a FACS-based facial expression recognition system and describe in more detail the implementation of two of its main components. Firstly we look at how features that are useful from a pattern analysis point of view can be extracted from a raw input image. We show that good results can be obtained by using the method of local binary patterns (LPB) to generate a large number of candidate features and then selecting from them using fast correlation-based filtering (FCBF). Secondly we show how Platt scaling can be used to improve the performance of an error-correcting output code (ECOC) classifier.
Impact of aging mechanism on model simulated carbonaceous aerosols (2012)

Carbonaceous aerosols including organic carbon and black carbon have significant implications for both climate and air quality. In the current global climate or chemical transport models, a fixed hydrophobic-to-hydrophilic conversion lifetime for carbonaceous aerosol (τ) is generally assumed, which is usually around one day. We have implemented a new detailed aging scheme for carbonaceous aerosols in a chemical transport model (GEOS-Chem) to account for both the chemical oxidation and the physical condensation-coagulation effects, where τ is affected by local atmospheric environment including atmospheric concentrations of water vapor, ozone, hydroxyl radical and sulfuric acid. The updated τ exhibits large spatial and temporal variations with the global average (up to 11 km altitude) calculated to be 2.6 days. The chemical aging effects are found to be strongest over the tropical regions driven by the low ozone concentrations and high humidity there. The τ resulted from chemical aging generally decreases with altitude due to increases in ozone concentration and decreases in humidity. The condensation-coagulation effects are found to be most important for the high-latitude areas, in particular the polar regions, where the τ values are calculated to be up to 15 days. When both the chemical aging and condensation-coagulation effects are considered, the total atmospheric burdens and global average lifetimes of BC, black carbon, (OC, organic carbon) are calculated to increase by 9% (3%) compared to the control simulation, with considerable enhancements of BC and OC concentrations in the Southern Hemisphere. Model evaluations against data from multiple datasets show that the updated aging scheme improves model simulations of carbonaceous aerosols for some regions, especially for the remote areas in the Northern Hemisphere. The improvement helps explain the persistent low model bias for carbonaceous aerosols in the Northern Hemisphere reported in literature. Further model sensitivity simulations focusing on the continental outflow of carbonaceous aerosols demonstrate that previous studies using the old aging scheme could have significantly underestimated the intercontinental transport of carbonaceous aerosols.
Characteristics of Edge-Emitting Bragg Reflection Waveguide Lasers (2010)

We demonstrate experimentally the stable continuous-wave (CW) single-mode operation of Bragg reflection waveguide (BRW) lasers from 10 to 100°C. The threshold characteristics, quantum efficiency, gain, and self-heating characteristics are investigated in detail. Threefold enhancement in the optical confinement is achieved using these BRW structures for a core width two times that of their edge-emitting total internal reflection counterparts. The device shows also the high gain and characteristic temperature (~197 K) under CW operation from 10 to 100°C. The mode stability is analyzed by the calculated mode reflection spectrum, injection-current-dependent lasing spectrum, and near-field patterns.
Diagnosis and Management of Pulmonary Arterial Hypertension: Implications for Respiratory Care (2006)

Pulmonary arterial hypertension (PAH) is a pathological condition of the small pulmonary arteries. PAH is characterized histopathologically by vasoconstriction, vascular proliferation, in situ thrombosis, and remodeling of all 3 levels of the vascular walls. These pathologic changes result in progressive increases in the mean pulmonary-artery pressure and pulmonary vascular resistance, which, if untreated, leads to right-ventricular failure and death. PAH can be associated with multiple conditions or risk factors (eg, collagen vascular diseases, liver disease, human immunodeficiency virus, congenital heart disease, or ingestion of certain medications or toxins) or it can be idiopathic. Up to 10% of the idiopathic cases are familial. Regardless of the etiology, the clinical presentation, histopathologic lesions, and response to therapy are all similar. Early in the disease process, the signs and symptoms of PAH are often subtle and nonspecific, making diagnosis challenging. Patients most often present with progressively worsening dyspnea and fatigue. An extensive evaluation is indicated to diagnose PAH, decipher its etiology, and determine long-term treatment goals. Transthoracic echocardiogram is an excellent screening tool to evaluate PAH, but every patient requires a right-side heart catheterization to help stage the disease and guide therapy. Prior to a decade ago, clinicians were only able to offer symptomatic therapy to this challenging group of patients. Earlier diagnosis, rapidly advancing understanding of the pathogenesis, and an increasing number of treatment options have changed the course of PAH, which was once thought to be invariably fatal.
Effect of Diffuser and Volute on Turbocharger Centrifugal Compressor Stability and Performance: Experimental Study (2011)

Engine downsizing is potentially one of the most effective strategies being explored to improve fuel economy. A main problem of downsizing using a turbocharger is the small range of stable functioning of the turbocharger centrifugal compressor at high boost pressures. Several techniques were studied to increase the compressor operating range without sacrificing the compressor efficiency. This paper presents the effect of delaying diffuser stability on the compressor performance and surge line. Two different techniques were investigated, these are grooved and pinched diffuser. Moreover, the effect on retracting volute tongue on compressor performance is also studied. Pinched diffuser shifted surge line to low flow rates, while dropping pressure through compressor. On the other hand, some interesting results were obtained when using grooved diffuser, these are pressure increase at high flow rates, and choke line shift to high flow rates. While retracting volute tongue was interesting in improving compressor efficiency, and pressure lines at high speed.
Design of novel multi-band printed dipole antennas fed by a modified microstrip ring hybrid (2013)

In this paper, novel printed dipole antennas fed from end to end are presented for multiple wireless services. Unlike conventional dipole antenna fed from the center, two dipole arms integrated with a modified three-port microstrip ring hybrid, whose sum port is opened, can achieve the model of end-to-end-fed dipole antenna. Because the phase difference and magnitude ratio of signals from two output ports of ring hybrid vary from frequency to frequency, balanced and unbalanced signals can excite dipole antenna with different resonance modes. Dual-band and multi-band novel printed dipole antennas which have simple geometries and can be directly fabricated on PCB board with single microstrip feed are constructed and tested. Proposed antennas are suitable for many wireless communication application, such as WLAN 2.4/5.2GHz, WiMAX 2.6/3.5GHz, ISM band, DCS1800, PCS1900, and UMTS cellular system, etc.
Changes in Cardiometabolic Risk Among Obese Older Adults After a 12-Month Exercise and Diet Intervention (2020)

Obesity imposes risk to cardiometabolic health; however, intentional weight loss in obese older adults remains controversial. Using data from the CROSSROADS Study (clinicaltrials.gov #NCT00955903), this ancillary study investigated effects of exercise with and without intentional weight loss on changes in cardiometabolic risk assessed by four risk-scoring tools. Participants (n = 134, 39% male, 23% African American, 70.2 ± 4.7 y) were randomized to exercise (n = 48), exercise + nutrient-dense weight maintenance diet (n = 44), or exercise + nutrient-dense caloric restriction of 500 kcals/day (n = 42). The following risk scores were calculated using baseline and 12-month data: Framingham risk assessment, Cardiometabolic Disease Staging (CMDS), metabolic syndrome classification by the International Diabetes Federation (IDF), and metabolic syndrome classification by the National Cholesterol Education Program's Adult Treatment Panel (ATP III). Generalized Estimating Equations were employed to determine differences between groups with ethnicity, sex, and age as covariates. Group-time interaction was not significant in application of IDF or ATPIII. Group-time interaction was significant for Framingham and CMDS (P = 0.005 and 0.041, respectively). Upon post-hoc analysis, significant within-group improvements in Framingham scores were observed for exercise + weight maintenance (P < 0.001, r = −1.682) and exercise + weight loss (P = 0.020, r = −0.881). In analysis of between-group differences in Framingham scores, a significant decrease was observed in the exercise + weight maintenance group (P = 0.001, r = −1.723) compared to the exercise group. For CMDS, the exercise + weight loss group had significant within-group improvements (P = 0.023, r = - 0.102). For between-group differences in CMDS, the exercise + weight loss group showed significant risk score reduction (P = 0.012, r = −0.142) compared to the exercise group. Risk assessment by Framingham and CMDS showed greater sensitivity to change in cardiometabolic risk factors. Results suggest obese older adults can lower cardiometabolic risk by engaging in exercise + weight maintenance or exercise + weight loss by moderate caloric restriction. R01AG033094 NIA, K07AG043588 NIA, P30DK056336 NIDDK.