gebhart/patrepeval huggingface dataset:
Catalogue of Additions to the Manuscripts in the British Museum: Plays submitted to the Lord Chamberlain 1824–1851. [London], The Trustees of the British Museum, 1964. Pp. x + 359. 10 × 6½ in £3. 17 s . 6 d . Catalogue of Additions to the Manuscripts in the British Museum: Plays submitted to the Lord Chamberlain 1824–1851. [London], The Trustees of the British Museum, 1964. Pp. x + 359. 10 × 6½ in £3. 17 s . 6 d . (1965)

Catalogue of Additions to the Manuscripts in the British Museum: Plays submitted to the Lord Chamberlain 1824–1851. [London], The Trustees of the British Museum, 1964. Pp. x + 359. 10 × 6½ in £3. 17s. 6d. Get access Catalogue of Additions to the Manuscripts in the British Museum: Plays submitted to the Lord Chamberlain 1824–1851. [London], The Trustees of the British Museum, 1964. Pp. x + 359. 10 × 6½ in £3. 17s. 6d. Michael Slater Michael Slater Search for other works by this author on: Oxford Academic Google Scholar The Library, Volume s5-XX, Issue 4, December 1965, Pages 333–335, https://doi.org/10.1093/library/s5-XX.4.333 Published: 01 December 1965
Supplementary File S1 from Interactions with Fibroblasts Are Distinct in Basal-Like and Luminal Breast Cancers (2023)

Supplementary File S1 from Interactions with Fibroblasts Are Distinct in Basal-Like and Luminal Breast Cancers
Iron and Nitrate Supply to Oregon Coastal Waters: Physical Mechanisms and Biological Response (2001)

Abstract : Iron and nitrate concentrations were measured at high-resolution underway in surface waters and in vertical profiles off the Oregon coast in July, 1999. Surface Fe and N (nitrate + nitrite) concentrations measured by flow injection analysis ranged from < 0.3 to 20 nmol 1(exp -1) and < 0.1 to 30 mu-mol 1(exp -1), respectively. Total dissolvable Fe concentrations, measured in unfiltered, acidified samples in surface waters and in vertical profiles, ranged from < 0.3 to 300 nmol 1(exp -1). Our observations indicate two dominant sources of Fe to Oregon coastal waters: Slope or shelf sediments, and the Columbia River. Sedimentary iron, largely in the particulate form, appears to be added to surface waters through wind-induced vertical mixing during strong winds; through thickening of the bottom mixed layer during relaxation or downwelling-favorable wind conditions; and by outcropping of shelf bottom-waters during upwelling events. The existence of multiple iron sources and the generally high (total) iron concentrations may explain why the distribution of phytoplankton - measured both remotely (by SeaWiFS) - and underway (by in-vivo fluorescence) - appeared to be driven primarily by physical dynamics, and was not obviously linked to the distribution of iron. Nevertheless, at some offshore stations where underway Fe was < 0.3 nmol 1(exp -1), underway measurements of the physiological state of phytoplankton by Fast Repetition Rate fluorometry were consistent with mild iron-stress.
Antiviral Nucleosides (1997)

Abstract: This article provides an overview of the field of nucleoside antiviral agents in so far as they have some level of current interest. It considers compounds in a number of structural classes: conventional nucleoside analogues, acyclics, carbocyclics, thio, heterosubstituted and those having "unnatural" L stereochemistry. In addition, it deals with important derivative subclasses such as phosphonate mimics of nucleotides. We indicate the current•status of leading compounds, which in many cases is clinical evaluation, and position with regard to licensing, and reflect the current level and style of activities within each particular class. Our other major objective has been to incorporate a review of the major publications appearing in the last two years in the area of antiviral nucleosides. This includes both biological and clinical studies as well as the more significant advances in synthetic approaches to compounds in all classes. We refer extensively throughout to other relevant review articles which have covered particular areas -of investigation or have dealt in depth with a single compound.
Ultrasonically induced necrosis through the rib cage based on adaptive focusing: ex vivo experiments (2004)

Ex vivo experiments have been conducted through excised lamb rib cages, with bone, cartilage, muscle and skin. The ribs were placed between a hydrophone and a programmable sparse array made of 200 high power transducers working at 1 MHz central frequency. First, adaptive focusing through ribs has been experimentally studied at low power. Without any correction, the pressure fields in the focal plane were affected by both inhomogeneous attenuation and phase distortion and three main effects were observed: a mean 2 mm shift of the main lobe, a mean 1.25 mm spreading in the half width of the main lobe and up to 20 dB increase in the secondary lobe level. Three adaptive focusing techniques were tested with continuous waves: phase shift, time reversal and time reversal coupled with amplitude compensation. We show that time reversal is more appropriate, as it minimizes the heating of the ribs by naturally sonicating between the ribs. It is also shown that a non invasive technique could be implemented by using the imaging capabilities of the therapeutic array.
Beat frequency of cilia from sites of purulent infection. (1986)

Mucociliary clearance depends on the interaction between cilia and mucus; it is delayed in the presence of purulent secretions. Nasal mucociliary clearance was examined by the saccharin method and nasal ciliary beat frequency by a photometric technique. Four groups were studied: normal controls, patients with bronchiectasis without nasal symptoms, patients with chronic mucopurulent sinusitis alone, and patients with chronic mucopurulent sinusitis and bronchiectasis. Nasal mucociliary clearance was prolonged in infected patients. Cilia obtained from the site of purulent secretions were found to beat more slowly in vitro (mucopurulent sinusitis 12.1 Hz, mucopurulent sinusitis and bronchiectasis 11.6 Hz), than those obtained from normal controls (14.3 Hz) and from patients with bronchiectasis alone (13.6 Hz). The cause of the ciliary slowing seemed most likely to be the release of host factors during the inflammatory response, rather than the particular organism isolated. Ciliary slowing may contribute to the observed delay of mucociliary clearance in conditions in which purulent secretions are present.
Migration Patterns of Nonspecifically Activated Versus Nonactivated Nonhuman Primate T Lymphocytes: Preferential Homing of Activated Autologous CD8+ T Cells in the Rectal Mucosa (2008)

Adoptive cell transfer may be a successful strategy in anticancer therapy and its therapeutic efficiency depends on the access of transferred cells to the tumor site and their persistence in vivo. Nevertheless, the migration properties of autologous in vitro-activated T cells in primates are largely unknown. Here, we established the long-term tracking of T-cell migration into various compartments of rhesus macaques as a preclinical model for the evaluation of T-cell–based immunotherapy. Peripheral blood mononuclear cells from 3 to 4 rhesus macaques were activated with anti-CD3/anti-CD28 or not, labeled with carboxyfluorescein diacetat succinimidyl ester, and reinjected intravenously into the donor animals. Blood samples, lymph node biopsies, and mucosal biopsies (duodenum, rectum) were collected at various time points and analyzed by flow cytometry for the presence of the reinjected T cells. We demonstrate that nonspecific in vitro activation changes the in vivo migratory behavior of T cells and provokes a preferential migration of CD8+ T cells to the rectum. Nonspecifically activated transferred CD4+ T cells were found in much lower frequencies at this site and also in other compartments. Thus, our results indicate an imbalanced distribution of autologous CD8+ and CD4+ T cells in various compartments that is more apparent when T cells are activated before the transfer. The migratory behavior of in vitro-expanded, autologously transferred T cells can, therefore, influence the clinical outcome of adoptive cell transfer.
Large-Scale Biometric Identification: Challenges and Solutions (2007)

In addition to law enforcement applications, many civil applications will require biometrics-based identification systems and a large percentage is predicted to rely on fingerprints as an identifer. Even though fingerprint as a biometric has been used in many identification applications, mostly these applications have been semi-automatic. The results of such systems often require to be validated by human experts. With the increased use of biometric identification systems in many realtime applications, the challenges for large-scale biometric identification are significant both in terms of improving accuracy and response time. In this paper, we briey review the tools, terminology and methods used in large-scale biometrics identification applications. The performance of the identification algorithms need to be significantly improved to successfully handle millions of persons in the biometrics database matching thousands of transactions per day.
Microbending loss in a single-mode fiber in the pure-bend loss regime (1982)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text S. K. Yao, C. K. Asawa, and G. F. Lipscomb, "Microbending loss in a single-mode fiber in the pure-bend loss regime," Appl. Opt. 21, 3059-3060 (1982) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Restless legs syndrome in Parkinson's disease (2009)

We aimed to investigate the prevalence of restless legs syndrome (RLS) according to essential diagnostic criteria, and to explore potential associations with clinical features, especially motor fluctuations, in a cohort of 113 patients with idiopathic Parkinson's disease (PD). Twenty-eight (24%) fulfilled essential diagnostic criteria for RLS. They were younger (63.1 +/- 8.6 vs. 68.8 +/- 9.0 years; P = 0.004), had an earlier onset of PD (54.1 +/- 9.5 vs. 59.2 +/- 10.3 years; P = 0.018), and received lower levodopa equivalent doses (578.4 +/- 382.2 vs. 779.1 +/- 459.6 mg/day; P = 0.04) than patients with PD who scored negative for RLS. In 23 patients (82%), RLS symptom onset was after PD onset (mean interval, 4.5 +/- 3.7 years). The majority (n = 17, 61%) who scored positive for RLS reported that the urge to move the legs and unpleasant sensations were associated with wearing off, raising the possibility of RLS mimics in fluctuating patients with PD.
Optimal control of vortex shedding using low-order models. Part II?model-based control (1999)

In Part I, an approach to deriving low-order models suitable for use in the development of active control strategies for separated flows was presented. The methodology proposed was applied to a numerical simulation of the incompressible, unsteady wake flow behind a circular cylinder at Re=100, with control action achieved via cylinder rotation. The resulting low-order models were found to predict the flows in four open-loop test cases with sufficient fidelity to justify their application in model-based control of the vortex-shedding flow. In Part II, optimal control theory is used to implement the model-based control, and data from numerical simulations of the controlled flow are presented. It is found that the level of wake unsteadiness can be reduced, even when the low-order model is reset on the basis of limited flow field information. The degree of reduction is dependent on the accuracy of the low-order model, and ways of refining it in the light of control simulations are considered. However, results from two straightforward approaches to this problem suggest that it is easy to ‘over-tune’ the model, resulting in less successful control. Copyright © 1999 John Wiley & Sons, Ltd.
Supplementary Legends from AKT Inhibition Promotes Nonautonomous Cancer Cell Survival (2023)

&lt;p&gt;Supplementary figures and datasets legends&lt;/p&gt;
Minimizing Moments of AoI for Both Active and Passive Users through Second-Order Analysis (2023)

In this paper, we address the optimization problem of moments of Age of Information (AoI) for active and passive users in a random access network. In this network, active users broadcast sensing data while passive users only receive signals. Collisions occur when multiple active users transmit simultaneously, and passive users are unable to receive signals while any active user is transmitting. Each active user follows a Markov process for their transmissions. We aim to minimize the weighted sum of any moments of AoI for both active and passive users in this network. To achieve this, we employ a second-order analysis to analyze the system. Specifically, we characterize an active user's transmission Markov process by its mean and temporal process. We show that any moment of the AoI can be expressed a function of the mean and temporal variance, which, in turn, enables us to derive the optimal transmission Markov process. Our simulation results demonstrate that this proposed strategy outperforms other baseline policies that use different active user transmission models.
Abstract PO-265: The intersection of sexual orientation with race and ethnicity in cervical cancer screening: Results from the National Health Interview Survey (2022)

Abstract Objectives: Cervical cancer screening is recommended for those with a cervix aged 21-65, with specific timelines dependent on individual risk. Persons belonging to sexual minority (SM) groups may experience greater risk factors for cancer while also being less likely to participate in cancer screening. We compared cervical cancer screening rates by sexual orientation, as well as intersectional analyses with race/ethnicity. Methods: Data from the NHIS years 2015 and 2018, were used to examine cervical cancer screening disparities. Biologic females without history of hysterectomy, ages 21-65 years, who reported sexual orientation and Pap testing history were included. Demographic, health, and cervical cancer screening characteristics were examined using descriptive statistics. Multivariable logistic regression models explored Pap testing rates by sexual orientation alone and with race/ethnicity (non-Hispanic (NH) white, NH Black, Hispanic), adjusting for age, partner status, education, health insurance, and poverty status. Results: SM participants (N=874) were younger, less likely to be living with a partner, had lower income, were less likely to have a medical clinic they go to for regular care, and more likely to delay their medical care due to costs, when compared to heterosexual counterparts (N=17,733). SM persons had significantly reduced odds of ever undergoing Pap testing (OR: 0.57, CI: 0.44-0.74) when compared to heterosexual persons. When considering the intersection of sexual orientation and race/ethnicity, heterosexual Hispanic, SM NH white, and SM Hispanic participants all had reduced odds of ever undergoing Pap testing when compared to NH white heterosexual participants. There were no significant differences observed between heterosexual and SM participants of NH Black or white identities. Conclusions: Participants identifying as SM were significantly less likely to have ever undergone a Pap test when compared to heterosexual participants. When stratifying by race/ethnicity, disparities remained for most participants identifying as SM. These results demonstrate a need for continued effort to increase Pap testing among the SM community. Further research is needed to further examine roles of systemic discrimination and other key drivers of these disparities. Citation Format: Ashley E. Stenzel, Gabriela Bustamante, Courtney Sarkin, Katherine Harripersaud, Patricia Jewett, Deanna Teoh, Rachel I. Vogel. The intersection of sexual orientation with race and ethnicity in cervical cancer screening: Results from the National Health Interview Survey [abstract]. In: Proceedings of the AACR Virtual Conference: 14th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2021 Oct 6-8. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2022;31(1 Suppl):Abstract nr PO-265.
The influence of malrotation and femoral component material on patellofemoral wear during gait (2011)

Complications involving the patellofemoral joint, caused by malrotation of the femoral component during total knee replacement, are an important cause of persistent pain and failure leading to revision surgery. The aim of this study was to determine and quantify the influence of femoral component malrotation on patellofemoral wear, and to determine whether or not there is a difference in the rate of wear of the patellar component when articulated against oxidised zirconium (OxZr) and cobalt-chrome (CoCr) components. An in vitro method was used to simulate patellar maltracking for both materials. Both rates of wear and changes in height on the patellar articular surface were measured. The mean rates of wear measured were very small compared to standard tibiofemoral wear rates. When data for each femoral component material were pooled, the mean rate of wear was 0.19 mm3/Mcycle (sd 0.21) for OxZr and 0.34 mm3/Mcycle (sd 0.335) for CoCr. The largest change in height on each patella varied from -0.05 mm to -0.33 mm over the different configurations. The results suggest that patellar maltracking due to an internally rotated femoral component leads to an increased mean patellar wear. Although not statistically significant, the mean wear production may be lower for OxZr than for CoCr components.
Effect of age on susceptibility to Salmonella Typhimurium infection in C57BL/6 mice (2009)

Ageing is associated with a decline in immune function, which predisposes the elderly to a higher incidence of infections. Information on the mechanism of the age-related increase in susceptibility to Salmonella enterica serovar Typhimurium (S. Typhimurium) is limited. In particular, little is known regarding the involvement of the immune response in this age-related change. We employed streptomycin (Sm)-pretreated C57BL/6 mice to develop a mouse model that would demonstrate age-related differences in susceptibility and immune response to S. Typhimurium. In this model, old mice inoculated orally with doses of 3 x 10(8) or 1 x 10(6) c.f.u. S. Typhimurium had significantly greater S. Typhimurium colonization in the ileum, colon, Peyer's patches, spleen and liver than young mice. Old mice had significantly higher weight loss than young mice on days 1 and 2 post-infection. In response to S. Typhimurium infection, old mice failed to increase ex vivo production of IFN-gamma and TNF-alpha in the spleen and mesenteric lymph node cells to the same degree as observed in young mice; this was associated with their inability to maintain the presence of neutrophils and macrophages at a 'youthful' level. These results indicate that Sm-pretreated C57BL/6 old mice are more susceptible to S. Typhimurium infection than young mice, which might be due to impaired IFN-gamma and TNF-alpha production as well as a corresponding change in the number of neutrophils and macrophages in response to S. Typhimurium infection compared to young mice.
Architectures for intelligent control systems: The science of autonomous intelligence (2002)

This new area of engineering (AICS), endeavor, architectures for intelligent control systems, has generated a number of often controversial results and directions. It is rooted in control theory, artificial intelligence, computer architectures, software engineering as well as in psychology, biology, linguistics, and other disciplines. A question arises: is this a science, or just an intersection of different scientific technologies and techniques? The author views AICS as a science, albeit not a typical one.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Correlation of Ultra-low Shear Rate Viscosity and Dynamic Barite Sag in Invert-Emulsion Drilling Fluids (1999)

The occurrence of barite sag has been a well recognized, but poorly understood phenomenon in the drilling industry. Problems such as lost circulation, well control and stuck pipe have resulted from the occurrence of barite sag. The financial impact of barite sag on drilling costs, usually resulting from rig-time lost while circulating and conditioning the mud system, is not trivial. There are reported incidences where recurring barite sag problems have resulted in the loss of drilling projects.Although originally thought to occur under static conditions, barite sag is now recognized to occur more readily under dynamic, low shear rate conditions. Industry experts have offered a variety of measuring parameters, based upon empirical data, that only partially correlate with the occurrence of barite sag. The prediction of barite sag in dynamic flow has created an engineering challenge.The effect of shear rate on dynamic barite sag, for invert-emulsion muds, has been studied and quantified using new and advanced technology. A new field viscometer, capable of measuring viscosity at shear rates of 0.0017 s-1, and an eccentric well-bore hydraulics model were used to develop and understand this relationship. Changes in mud weight as a function of shear rate, hole angle, annular velocity and eccentricity correlate with ultra-low shear rate viscosity.Based upon experimental results, field technology has been developed to predict the potential for barite sag of invert-emulsion muds and to provide remedial measures through ultra-low shear rate viscosity modification. The efficacy of using traditional rheological measurements as indicators of barite sag potential are addressed.
Carbon and oxygen role for thermally induced microdefect formation in silicon crystals (1979)

Thermally induced microdefect formation phenomena are investigated in connection with oxygen and carbon in silicon crystals by using x-ray diffraction, infrared absorption, and etching/optical microscope observation techniques. In order to investigate the carbon and oxygen role for microdefect formation, oxygen-diffused floating-zone-grown silicon crystals, containing various carbon contents, are thermally treated. As a result, it is ascertained that the coexistence of both carbon and oxygen is necessary for the microdefect formation. It is also determined that the critical oxygen concentration for microdefect introduction by the heat treatment is about (5–6) ×1017 cm−3.
Oxygen etching of thick MoS2films (2014)

Oxygen annealing of thick MoS2 films results in randomly oriented and controllable triangular etched shapes, forming pits with uniform etching angles. These etching morphologies differ across the sample based on the defect sites situated on the basal plane surface, forming numerous features in different bulk sample thicknesses.
Plasma Levels of Atrial Natriuretic Peptide in Primary Aldosteronism and Essential Hypertension (1986)

Plasma levels of atrial natriuretic peptide (ANP) were measured in 9 patients with primary aldosteronism and 41 patients with essential hypertension (class I or II by WHO classification) using a specific and sensitive RIA. The mean plasma ANP concentration in patients with primary aldosteronism (mean +/- SEM, 67.1 +/- 10.8 pg/ml; n = 9) was significantly higher than that in healthy normotensive subjects (37.9 +/- 1.4 pg/ml; n = 108) or patients with essential hypertension (38.5 +/- 2.8 pg/ml; n = 41). During treatment with spironolactone, plasma levels of ANP declined in 6 of the 7 patients with primary aldosteronism, but no change occurred in the remaining patient who had cardiac enlargement of unknown etiology. The mean plasma ANP concentration in patients with essential hypertension, on the other hand, was not significantly different from that in normal subjects. These results indicate that plasma ANP levels are elevated in patients with primary aldosteronism, probably due to volume expansion, whereas no abnormality in ANP secretion exists in patients with uncomplicated essential hypertension.