gebhart/patrepeval huggingface dataset:
Prevalence and risk factors of Strongyloides stercoralis infection among Orang Asli schoolchildren: new insights into the epidemiology, transmission and diagnosis of strongyloidiasis in Malaysia (2019)

This cross-sectional study aimed to determine the prevalence and risk factors of S. stercoralis infection among 1142 Orang Asli primary schoolchildren in six different states of Peninsular Malaysia. Fecal samples were examined using direct smear, formalin-ether sedimentation (FES), agar plate culture (APC) and PCR techniques. Overall, 15.8% of the children were found to be infected with S. stercoralis. The prevalence was 0.2, 1.3, 15.2 and 13.7% by direct smear, FES, APC and PCR, respectively. Multivariate analysis showed that an age of >10 years, being male, belonging to a Proto-Malay tribe, belonging to the Senoi tribe, indiscriminate defecation, using an unimproved water source for drinking water and not wearing shoes when outside were the significant risk factors of infection among these children. In conclusion, we provide new evidence on the occurrence of S. stercoralis in Malaysia to show that there is a relatively high prevalence of infection among Orang Asli schoolchildren. Therefore, the use of specific methods for detecting S. stercoralis should be considered when screening these children for intestinal parasites. Moreover, prevention and control measures specific to S. stercoralis should be integrated into the intestinal parasitic infections control programme in Malaysia.
New Trends in Location-Based Services Technology (2022)

Location-Based Services are constantly evolving with the passage of time due to the advancement in technology. The current paper has presented new trends in Location-Based Services technology. The localization infrastructure for LBS includes LBS Indoor Systems, LBS Satellite Systems, LBS GPS System
A system to detect cerebral aneurysms in multimodality angiographic data sets (2014)

The authors present an automatic system to detect cerebral aneurysms in multimodal angiographic data sets. The system proved as a suitable computer-aided detection tool to help radiologists find cerebral aneurysms.
Testing of a Full-Scale Staged Combustor Operating With a Synthetic Liquid Fuel (1983)

The staged rich-lean gas turbine engine combustion system has been the subject of numerous investigations directed at substantiating the capability of burning nitrogen bearing fuels without producing high emissions of nitric oxides. Many tests conducted to evaluate the potential of this combustion system when operating with coal-derived liquid fuels have been conducted using subscale burners because of the high cost and limited quantities of fuel available (e.g., (1–3). Questions arise as to the applicability of the subscale test findings when predicting the capabilities of full scale devices. In order to evaluate the efficacy of applying subscale results to large scale devices, a program was undertaken to test a 25-cm dia staged rich-lean combustor having similar characteristics to a previously tested 12.5-cm dia combustor and to identify areas where scale effects prove to be critical.
Impaired Function of the Tonoplast-Localized Sucrose Transporter in Rice, OsSUT2, Limits the Transport of Vacuolar Reserve Sucrose and Affects Plant Growth (2011)

Physiological functions of sucrose (Suc) transporters (SUTs) localized to the tonoplast in higher plants are poorly understood. We here report the isolation and characterization of a mutation in the rice (Oryza sativa) OsSUT2 gene. Expression of OsSUT2-green fluorescent protein in rice revealed that OsSUT2 localizes to the tonoplast. Analysis of the OsSUT2 promoter::β-glucuronidase transgenic rice indicated that this gene is highly expressed in leaf mesophyll cells, emerging lateral roots, pedicels of fertilized spikelets, and cross cell layers of seed coats. Results of Suc transport assays in yeast were consistent with a H(+)-Suc symport mechanism, suggesting that OsSUT2 functions in Suc uptake from the vacuole. The ossut2 mutant exhibited a growth retardation phenotype with a significant reduction in tiller number, plant height, 1,000-grain weight, and root dry weight compared with the controls, the wild type, and complemented transgenic lines. Analysis of primary carbon metabolites revealed that ossut2 accumulated more Suc, glucose, and fructose in the leaves than the controls. Further sugar export analysis of detached leaves indicated that ossut2 had a significantly decreased sugar export ability compared with the controls. These results suggest that OsSUT2 is involved in Suc transport across the tonoplast from the vacuole lumen to the cytosol in rice, playing an essential role in sugar export from the source leaves to sink organs.
Modeling Spontaneous Emission Control in Photonic Crystals by Ferromagnetic Resonance (2013)

The radiation dynamics of a magnetic dipole located inside a photonic crystal has been considered as an analogue for optical emission of a point-like emitter in such a crystal. We have experimentally realized this situation by fixing a single crystal yttrium iron garnet (YIG) sphere of 1.7 mm diameter inside a photonic crystal consisting of dielectric alumina rods. These rods form a woodpile structure of size 16 × 6 × 6 cm3 . The photonic crystal shows a band gap at microwave frequencies between 12.9 and 14.3 GHz as calculated and verified from the transmission characteristics of the crystal. The radiation feedback of the YIG sphere was probed by ferromagnetic resonance experiments covering a large frequency range from 8 to 17 GHz. Whereas outside the band gap the radiation-induced linewidth amounts up to 30 Oe, it is almost completely suppressed inside the gap. From the full analysis of linewidth and resonance shift, we could clearly prove the non-Markovian character of the radiation dynamics at the edges of the gap as expected from theory. The experimental control of spontaneous emission, as realized in our experiment, is a very promising step towards future optical applications in low threshold lasers, highly efficient light emitting diodes or photovoltaic solar modules.
Las cinco mentes de un directivo (2004)

El articulo se cuestiona que es y que significa pensar como un directivo. Para ello se plantea la presente confusion existente entre mentalidad de gerente y liderazgo, que, segun los autores, es la mayor causa de problemas en la gestion de empresas. Para los autores, en el desarrollo de la mentalidad de un directivo se han de gestionar los siguientes puntos basicos: gestionar el yo o la mentalidad reflexiva; gestionar las organizaciones o la mentalidad analitica; gestionar el contexto o la mentalidad mundana; gestionar las relaciones o la mentalidad de colaboracion; y por ultimo gestionar el cambio o la mentalidad de la accion. Este es el universo que los autores desarrollan en el articulo.
Assessing Cytochrome P450 and UDP-Glucuronosyltransferase Contributions to Warfarin Metabolism in Humans (2009)

As a step toward exploring a targeted metabolomics approach to personalized warfarin (Coumadin) therapy, we developed a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method capable of quantifying specific enantiomeric (R and S) contributions of warfarin (WAR) and the corresponding hydroxywarfarins (OH-WAR) and glucuronides (-GLUC) generated by cytochrome P450s (CYP) and UDP-glucuronosyltransferases (UGTs), respectively. Evaluation of quality control samples and three commercially available human samples showed that our analytical approach has the ability to measure 24 unique WAR metabolites in human urine. Evaluation of the human data also provides new insights for evaluating WAR toxicity and begins characterizing important UGT metabolic pathways responsible for WAR detoxification. Data revealed the significance of specific metabolites among patients and the corresponding enzymatic capacity to generate these compounds, including the first report of direct WAR glucuronidation. On the basis of total OH-WAR levels, (S)-7-OH-WAR was the predominant metabolite indicating the significance of CYP2C9 in WAR metabolism, although other CYP2C enzymes also contributed to clearance of this isomer. (R)-WAR hydroxylation to OH-WARs was more diverse among the patients as reflected in varying contributions of CYP1A2 and multiple CYP2C enzymes. There was wide variation in the glucuronidation of WAR and the OH-WARs with respect to the compounds and patients. 6- and 7-OH-WAR were primarily (>70%) excreted as glucuronides unlike 4'-OH-WAR and 8-OH-WAR. For all patients, UGT1A1 is likely responsible for 6-O-GLUC production, although UGT1A10 may also contribute in one patient. 7-O-GLUC levels reflected contributions from potentially five different UGT1A enzymes. In all cases, WAR, 4'-OH-WAR, 8-OH-WAR, and the corresponding glucuronides were minor metabolites with respect to the others. Taken together, these data suggest that both P450 and UGT reactions contribute to the generation of excretable products in human urine, thereby generating complex metabolic networks.
Organic reactions in aqueous media - with a focus on carbon-carbon bond formation (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOrganic reactions in aqueous media - with a focus on carbon-carbon bond formationChao Jun. LiCite this: Chem. Rev. 1993, 93, 6, 2023–2035Publication Date (Print):September 1, 1993Publication History Published online1 May 2002Published inissue 1 September 1993https://pubs.acs.org/doi/10.1021/cr00022a004https://doi.org/10.1021/cr00022a004research-articleACS PublicationsRequest reuse permissionsArticle Views6776Altmetric-Citations1155LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Evaluating nanoscale molecular homogeneity in extreme ultraviolet resists with nanoprojectile secondary ion mass spectrometry (2022)

Characterizing chemical changes in photoresists during fabrication processes is critical to understanding how nanometric defects contribute to film stochastics. We used nanoprojectile secondary ion mass spectrometry (NP-SIMS) to evaluate the nanoscale homogeneity of components in positive-tone extreme ultraviolet resists. NP-SIMS was operated in the event-by-event bombardment/detection mode, where a suite of individual gold nanoprojectiles separated in time and space stochastically bombard the surface. Each impact ejects secondary ions from a volume 10 to 15 nm in diameter and up to 10 nm in depth allowing for analysis of colocalized moieties with high spatial resolution. Individual partially exposed extreme ultraviolet resists were analyzed after light exposure, postexposure bake, and development. Results showed an expected increase in protonated quencher versus exposure dose, while after development, we observed increased abundance in the remaining film. The latter, we attribute to poor solubility in the developing solvent. Examining the photoacid generator (PAG), we found decreased PAG cation abundance versus exposure dose in the exposed films, likely due to photodecomposition of the PAG cation. Moreover, after the development, we observed decreased homogeneity of PAG ions, which we attribute to preferential extraction caused by ion-exchange interactions with the developer. We found that the insoluble moieties persisting on the surface after the development were relatively rich in the protecting group, likely due to uneven deprotection of the polymer. Overall, NP-SIMS allows to characterize the resist at the nanoscale and identify conditions that lead to defect formation.
Single mode fiber MT-RJ SFF transceiver module using optical sub assembly with a new shielded silicon optical bench (2002)

Recently, strong demands for compactness and drastic cost reduction of optical transceivers are arising. Small Form Factor (SFF) optical transceivers are expected to meet these demands. The new conceptual optical module based on v-grooved silicon optical bench (SiOB) technology, that enables a passive alignment of optical fibres and optical devices is also expected to reduce the cost drastically. MT-RJ SFF optical transceivers require this new packaging technique because the distance between input and output optical axes is shorter than conventional transceivers. However, crosstalk between a transmitter and a receiver is a big issue to be solved because the distance between optical axes of the Laser diode (LD) and the Photo diode (PD) is only 0.75 mm. Especially, it is difficult to reduce the crosstalk in a SiOB because large electromagnetic coupling exists due to the conductivity of a silicon substrate. In this paper, a newly developed, low crosstalk optical sub assembly (OSA) with a single mode fiber MT-RJ receptacle and the SFF transceiver module using it are reported. We have analyzed a mechanism of electrical crosstalk in a SiOB and developed a shield structure to reduce it. The crosstalk in the OSA with shielded SiOB was reduced over 20 dB compared to the unshielded SiOB.
Supplementary Figure 2 from Temozolomide-Mediated Radiosensitization of Human Glioma Cells in a Zebrafish Embryonic System (2023)

Supplementary Figure 2 from Temozolomide-Mediated Radiosensitization of Human Glioma Cells in a Zebrafish Embryonic System
Supplemental Figure 1 from Measurement of Ovarian Tumor Immune Profiles by Multiplex Immunohistochemistry: Implications for Epidemiologic Studies (2023)

&lt;p&gt;Supplemental Figure 1 provides representative images from the T cell panel for high-grade serous, endometrioid, clear cell, and mucinous tumors.&lt;/p&gt;
Reticular Chemistry: Occurrence and Taxonomy of Nets and Grammar for the Design of Frameworks (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
Incidence and management of myelosuppression in patients with chronic- and accelerated-phase chronic myeloid leukemia treated with omacetaxine mepesuccinate (2015)

Omacetaxine mepesuccinate (Synribo) is an inhibitor of protein synthesis indicated for the treatment of patients with chronic- or accelerated-phase chronic myeloid leukemia (CML) with resistance and/or intolerance to two or more tyrosine kinase inhibitors. Myelosuppression is the most common and clinically significant toxicity experienced by patients treated with omacetaxine. Here, we further examine the patterns of hematologic toxicity observed in clinical trials and describe the approach to management as well as resolution of events. Omacetaxine-related myelosuppression typically occurs more frequently during induction cycles. In general, the myelosuppression observed with omacetaxine treatment is manageable and reversible, and long-term administration is feasible. Careful monitoring, dose delays and reduction in administration days, and appropriate supportive care are critical for successful management of hematologic toxicity. Concerns regarding myelosuppression, observed with many cancer treatments, should not prevent eligible patients from receiving omacetaxine, particularly CML patients with unsatisfactory responses to multiple lines of prior treatment.
Treating Vaginal Laxity Using Nonablative Er:YAG Laser: A Retrospective Case Series of Patients From 2.5 Years of Clinical Practice (2020)

The results have confirmed that patients suffering from vaginal laxity can be effectively treated using the nonablative Er:YAG IntimaLase procedure without adverse effects. Mitsuyuki M, Štok U, Hreljac I. Treating Vaginal Laxity Using Nonablative Er:YAG Laser: A Retrospective Case Series of Patients From 2.5 Years of Clinical Practice. Sex Med 2020;8:265-273.
<title>Imaging of human colon carcinoma thin sections by FT-IR microspectrometry</title> (1998)

FTIR microspectroscopic maps of unstained colon carcinoma thin sections were obtained on a conventional IR microscope equipped with an automatic x, y stage, or alternatively by using a MCT focal plane array detector system. IR data were analyzed by different image re-assembling techniques. One main goal of the present study was to test the influence of different spectra data compression approaches on the quality of the FTIR images. The images, re-assembled by Principal component analysis (PCA) on the basis of spectral information available from the fingerprint region exhibited an excellent image contrast confirming standard histo- pathological examinations. The second approach included a systematic search for spectral windows which were supposed to contain the relevant information, necessary for spectra classification and identification. Data from these spectral windows were analyzed by an ANN and output data were utilized for image construction. In contrast to the PCA approach, the image contrast was lower although the main morphological structures were exactly classified. From the spectroscopic point of view, the spectral feature selection method delivered useful information which could be discussed in terms of structural alternations upon carcinogenesis.
B cell– and T cell–intrinsic regulation of germinal centers by thymic stromal lymphopoietin signaling (2023)

Long-lived and high-affinity antibodies are derived from germinal center (GC) activity, but the cytokines that regulate GC function are still being identified. Here, we show that thymic stromal lymphopoietin (TSLP) signaling regulates the GC and the magnitude of antigen-specific antibody responses. Both GC B cells and T follicular helper (T<sub>FH</sub>) cells up-regulate the expression of surface TSLP receptor (TSLPR), but cell-specific loss of TSLPR results in distinct effects on GC formation and antibody production. TSLPR signaling on T cells supports the retention of antigen-specific B cells and T<sub>FH</sub> differentiation, whereas TSLPR in B cells regulates the generation of antigen-specific memory B cells. TSLPR in both cell types promotes interferon regulatory factor 4 (IRF4) expression, which is important for efficient GC activity. Overall, we identified a previously unappreciated cytokine regulator of GCs and identified how this signaling pathway differentially regulates B and T cell responses in the GC.
Complete Genome Sequence of an Avian Polyomavirus Strain First Isolated from a Pigeon in China (2019)

Avian polyomavirus can infect multiple bird species and cause inflammatory disease with high mortality in young psittacine birds. In this study, we sequenced and analyzed an avian polyomavirus isolated from a pigeon in China, strain APV-P, which is closely related to a polyomavirus in psittacine birds.
Adenomatous polyposis coli protein contains two nuclear export signals and shuttles between the nucleus and cytoplasm (2000)

Mutational inactivation of the adenomatous polyposis coli (APC) tumor suppressor initiates most hereditary and sporadic colon carcinomas. Although APC protein is located in both the cytoplasm and the nucleus, the protein domains required to maintain a predominantly cytoplasmic localization are unknown. Here, we demonstrate that nuclear export of APC is mediated by two intrinsic, leucine-rich, nuclear export signals (NESs) located near the amino terminus. Each NES was able to induce the nuclear export of a fused carrier protein. Both APC NESs were independently able to interact with the Crm1 nuclear export factor and substitute for the HIV-1 Rev NES to mediate nuclear mRNA export. Both APC NESs functioned within the context of APC sequence: an amino-terminal APC peptide containing both NESs interacted with Crm1 and showed nuclear export in a heterokaryon nucleocytoplasmic shuttling assay. Also, mutation of both APC NESs resulted in the nuclear accumulation of the full-length, approximately 320-kDa APC protein, further establishing that the two intrinsic APC NESs are necessary for APC protein nuclear export. Moreover, endogenous APC accumulated in the nucleus of cells treated with the Crm1-specific nuclear export inhibitor leptomycin B. Together, these data indicate that APC is a nucleocytoplasmic shuttle protein whose predominantly cytoplasmic localization requires NES function and suggests that APC may be important for signaling between the nuclear and cytoplasmic compartments of epithelial cells.
Silver-titania/polyurethane composite nanofibre mat for chemical and biological warfare protection (2013)

The silver-titania nanoparticles with various silver contents were prepared by introducing the silver onto titania surface. Presence of silver was confirmed by various analyses. Compared to neat titania nanoparticle, the silver-titania nanoparticle exhibits better visible light photocatalytic degradation of methylene blue. Loading of silver onto titania leads to an enhancement of the visible light photocatalytic activity. The nanoparticles show good antimicrobial activities against E. coli. It is due to the loaded silver with excellent antimicrobial activity. Next, the silver-titania spreaded polyurethane composite nanofibre mat (CNM) for protection layer of protective clothing material was prepared using simultaneous process of electrospinning and electrospray. The electrosprayed silver-titania nanoparticles are well dispersed on the surface of polyurethane nanofibres. Compared to neat polyurethane nanofibre mat, the CNM shows a better photocatalytic degradation of dimethyl methylphosphonate (DMMP) under visible light and UV-A irradiation for 60 min. The CNM shows good antimicrobial activities against S. aureus.
Correction: Folate Receptor-α (FOLR1) Expression and Function in Triple Negative Tumors (2015)

The tenth author’s name is spelled incorrectly. The correct name is: Alvaro Moreno-Aspitia.

The Academic Editor field is missing from the published paper. The name of the Academic Editor is: Aamir Ahmad, Wayne State University School of Medicine, United States.
Image Synthesis with a Convolutional Capsule Generative Adversarial Network- Dataset (2019)

<strong>Dataset of 152 two-photon images (512x512) of axons with segmentation labels. </strong> We combined data from two published sources (Bass et al., 2017; Canty et al., 2018) to get 152 (512×512) 2D images (produced from 3D image stacks), and manually produced the corresponding labels. These images were collected using in-vivo two-photon microscopy from the mouse somatosensory cortex. To generate the 2D images, we used a max projection over the 3D stack. The labels are binary segmentation maps of the axons. This dataset is split into a train (132 images) and test (20 images) sets. The raw 2D images of axons are in /original folder, and the segmentation labels are in /mask folder. <strong>Please cite the following paper when using this dataset:</strong> Bass, C., Dai, T., Billot, B., Arulkumaran, K., Creswell, A., Clopath, C., De Paola, V., and Bharath, A. A., 2019. “Image synthesis with a convolutional capsule generative adversarial network,” <em>Medial Imaging with Deep Learning.</em> <strong>This dataset was complied from the following publications:</strong><br> Bass, C., Helkkula, P., De Paola, V., Clopath, C. and Bharath, A.A., 2017. Detection of axonal synapses in 3D two-photon images. PloS one, 12(9), p.e0183309.<br> Canty, A.J., Jackson, J.S., Huang, L., Trabalza, A., Bass, C., Little, G. and De Paola, V., 2018. Single-axon-resolution intravital imaging reveals a rapid onset form of Wallerian degeneration in the adult neocortex. <em>bioRxiv</em>, p.391425.