gebhart/patrepeval huggingface dataset:
The Radius of PSR J0740+6620 from NICER with NICER Background Estimates (2022)

Abstract We report a revised analysis for the radius, mass, and hot surface regions of the massive millisecond pulsar PSR J0740+6620, studied previously with joint fits to NICER and XMM-Newton data by Riley et al. (2021) and Miller et al. (2021). We perform a similar Bayesian estimation for the pulse-profile model parameters, except that instead of fitting simultaneously the XMM-Newton data, we use the best available NICER background estimates to constrain the number of photons detected from the source. This approach eliminates any potential issues in the cross-calibration between these two instruments, providing thus an independent check of the robustness of the analysis. The obtained neutron star parameter constraints are compatible with the already published results, with a slight dependence on how conservative the imposed background limits are. A tighter lower limit causes the inferred radius to increase, and a tighter upper limit causes it to decrease. We also extend the study of the inferred emission geometry to examine the degree of deviation from antipodality of the hot regions. We show that there is a significant offset to an antipodal spot configuration, mainly due to the non-half-cycle azimuthal separation of the two emitting spots. The offset angle from the antipode is inferred to be above 25° with 84% probability. This seems to exclude a centered-dipolar magnetic field in PSR J0740+6620.
Ultra-High Speed Optical Packet Switching System and Related Technologies (2007)

We propose and experimentally demonstrate a prototype 160 Gbit/s/port colored optical packet switch with all-optical multiple label processor and high-speed optical switch. As related technologies, arrayed burst mode Tx./Rx., 10 GbE/optical packet converter, and a novel transient response suppressed EDFA are also proposed and experimentally demonstrated.
The physiological role of the lymphoid system, 3. Leucophilic gamma-globulin and the phagocytic activity of the polymorphonuclear leucocyte. (1967)

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
Incorporating the Strength Provided by Subgrade Stabilization in the Flexible Pavement Design Procedures (2017)

Abstract Chemical stabilization has been successfully used to treat weak subgrade soil by permanently changing its physical and chemical properties, such as reducing plasticity and increasing stiffness and load bearing capacity, so it can serve as a construction platform during constructions and provide long-term structural stability. The Ohio Department of Transportation (ODOT) has adopted a policy to globally stabilize the subgrade for new construction. However, the strength provided by subgrade stabilization has not been incorporated into the design procedures for flexible pavement. Therefore, in this study, the impact of subgrade stabilization on the stiffness and performance of pavement layers was investigated. In situ testing, including the falling weight deflectometer (FWD) and the portable seismic pavement analyzer (PSPA), was performed on 20 pavement sections within the state of Ohio to evaluate pavement sections constructed with stabilized subgrade. Backcalculation of pavement layers’ moduli was carried out on the FWD data collected. Finite element analysis was performed using ABAQUS to validate the pavement layers’ stiffness obtained from backcalculation. The validated layer moduli were used to determine structural numbers and layer coefficients of pavement layers. The result was used to investigate the effect of subgrade stabilization on pavement design procedures. Significant reduction in the pavement thickness and distress was obtained as a result of incorporating subgrade stabilization into pavement design procedures.
Identification and Analysis of cDNA Clones Complementary to Abundant Oocyte-Specific Transcripts of Drosophila Melanogaster (1983)

Two hundred and fifty eDNA clones from a library derived from late stage egg chamber (stages 11-14) poly A+ RNA from Drosophila melanogaster were screened by colony and dot hybridization procedures. Six clones were shown to be complementary to maternally transmitted poly A+ RNA present during embryonic development. Hybridizations with 5'-32P-poly A+ mRNA probes isolated from 0-2 hr, 8-10 hr, and 18-20 hr embryos revealed that poly A+ RNA transcripts complementary to all six clones were present in all of the embryonic stages examined. Hybridizations with poly A+ RNA prepared from purified mitochondria and from tumorous female sterile (fes) mutant abdomens indicated that messages for five of the six clones were associated with the mitochondrial fraction. Clone cDml2 hybridized only to messages present in late stage egg chambers and embryonic stages, but not to messages associated with mitochondria or adult males. Characterization of the clones has shown that the respective eDNA inserts range from 440 to 625 bp in length. Clone cDml2 contains a 625 bp insert and restriction sites for both BamHI and Psti. The stage and tissue specificity of the mRNA complementary to this clone suggests this message or its translation product is a key ooplasmic component that may be necessary for embryonic development.
Integer Programming Formulation for Grouping Clusters in Ferry-assisted DTNs (2012)

Communication among isolated networks (clusters) in delay tolerant networks (DTNs) can be supported by a message ferry, which collects bundles from clusters and delivers them to a sink node. When there are lots of distant static clusters, multiple message ferries and sink nodes will be required. In this paper, we aim to make groups each of which consists of physically close clusters, a sink node, and a message ferry. Our main objective is minimizing the overall mean delivery delay of bundles in consideration of both offered load of clusters and distance between clusters and their sink nodes. We first model this problem as a nonlinear integer programming, based on the knowledge obtained in our previous work. Because it might be hard to solve this problem directly, we take two-step optimization approach based on linear integer programming, which yields an approximate solution of the problem. Through numerical results, we show the two-step optimization approach works well.
Use of dilatometer to screen refractory raw materials (2021)

Abstract Sudden shortage of a particular raw material due to freight disruptions, competitive market, and COVID restrictions have frequently forced the refractory industry to rapidly develop alternative formulations using available low‐cost materials. These alternative ingredients might cursorily appear to have similar total impurity content, but the presence of certain impurity combinations depending on the refractory type can produce more fluid liquid phase at high temperature, thereby drastically reducing hot strength. Undetected by the commonly used X‐ray fluorescence (XRF) analysis, the low‐cost material might differ in mineral‐phase content, whose phase transformations during firing might create excessive expansion producing warpage of the refractory along with a high porosity reducing strength and corrosion resistance. Finally, those cheap raw materials might have similar sieve analysis to that of the standard ingredient but might have much lower tapped density, which would introduce detrimental porosity into the resulting refractory. Hence, time‐consuming trials are often performed. Dilatometer studies on pressed or cast samples in a single test can identify reaction temperatures of spinel or mullite formation, which expand during firing, along with the amount of expansion and exact times at which firing needs to be done. It can also compare relative shrinkage due to liquid‐phase formation among impure raw materials like recycled grogs or low‐grade ores. Finally, dilatometric step scan is shown as a fast technique to prepare in‐house, low‐cost reactive spinel powder, which can also work for mullite.
Mechanisms of Cell Cycle Control Revealed by a Systematic and Quantitative Overexpression Screen in S. cerevisiae (2008)

Regulation of cell cycle progression is fundamental to cell health and reproduction, and failures in this process are associated with many human diseases. Much of our knowledge of cell cycle regulators derives from loss-of-function studies. To reveal new cell cycle regulatory genes that are difficult to identify in loss-of-function studies, we performed a near-genome-wide flow cytometry assay of yeast gene overexpression-induced cell cycle delay phenotypes. We identified 108 genes whose overexpression significantly delayed the progression of the yeast cell cycle at a specific stage. Many of the genes are newly implicated in cell cycle progression, for example SKO1, RFA1, and YPR015C. The overexpression of RFA1 or YPR015C delayed the cell cycle at G2/M phases by disrupting spindle attachment to chromosomes and activating the DNA damage checkpoint, respectively. In contrast, overexpression of the transcription factor SKO1 arrests cells at G1 phase by activating the pheromone response pathway, revealing new cross-talk between osmotic sensing and mating. More generally, 92%-94% of the genes exhibit distinct phenotypes when overexpressed as compared to their corresponding deletion mutants, supporting the notion that many genes may gain functions upon overexpression. This work thus implicates new genes in cell cycle progression, complements previous screens, and lays the foundation for future experiments to define more precisely roles for these genes in cell cycle progression.
A Review on the Use of Sodium Triacetoxyborohydride in the Reductive Amination of Ketones and Aldehydes (2007)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
CHROMOSOMAL LOCALIZATION OF REPETITIVE DNA IN THE NEWT, TRITURUS (1972)

The repetitive DNA sequences of the newt, Triturus viridescens, have been studied by nucleic acid hybridization procedures. Complementary RNA was synthesized enzymatically from unfractionated newt DNA. This RNA hybridized strongly to the centromeric regions of both somatic and lampbrush chromosomes It also bound to other loci scattered along the lengths of the chromosomes The amplified ribosomal DNA in the multiple oocyte nucleoli was demonstrated by in situ hybridization
Receiver-Based Auralization of Broadband Aircraft Flyover Noise Using the NASA Auralization Framework (2018)

The NASA Auralization Framework (NAF) consists of a set of dynamic link libraries (DLLs) to facilitate auralization of aircraft noise. Advanced capabilities for synthesis, propagation, and external interfaces are provided by the NAF Advanced Plugin Libraries (APL); a separate set of DLLs that are made accessible through the NAFs plugin architecture. In the typical time domain use case, the sound is first synthesized at the source location based on a source noise definition, and is then propagated in the time domain to a receiver on or near the ground. Alternatively, it may be desirable to synthesize the sound at the receiver, after it has been propagated in the frequency domain, e.g., when the source definition is inaccessible or when alternative propagation methods are needed. Receiver-based auralization requires three new developments in the NAF APL: a component plugin to interpolate the propagated noise spectra as a function of time for input to sound synthesis, and a path finder and path traversal plugin to calculate the effects of the differential propagation path length between the direct and ground reflected rays. This paper describes those developments and demonstrates their use in the auralization of broadband flyover noise.\n
Lossy filter synthesis of L-band planar filters using novel software (2011)

Lossy synthesis techniques are used to synthesize high performance filters using resonators with a finite Q. With these techniques a transmission response of a lossless filter with lowest possible roll-off is obtained, except for an overall constant additional insertion loss. The out-of band performance is not affected. These types of filters are useful in receiver architectures where the filter can be placed following an amplifying stage and some increase in insertion loss can be tolerated without affecting the noise figure. Due to the lower resonator Q that can be employed, low cost and compact filters (such as microstrip filters) can be realized.
Hence this work presents the synthesis and design of two planar lossy filters. Both filters have been designed using microstrip technology, with center frequencies of 1 GHz and 1.6 GHz, and bandwidth of 36 MHz and 80 MHz, respectively. Both filters exhibit a flat in-band response with an insertion loss of 10 dB and 7.5 dB, respectively. The topologies obtained from the synthesis result in a 4th and a 6th order filters at 1 GHz and 1.6 GHz, respectively. Both topologies present a uniform Q distribution throughout the networks, this is all the resonators of the filter are equal to 200 and 290, respectively. In contrast with conventional filter networks, where all the couplings are reactive, lossy filters require some of the couplings to be resistive. The main difference between the two filters presented is the type of frequency response. While the filter at 1 GHz synthesizes a response with a stopband 10 dB return loss, the filter at 1.6 GHz synthesizes a purely reflective response in the stopband.
The presentation will also show details of the software package that has been written to synthesize filters following various forms of pre-distortion, classical (no-loss considered in the synthesis) and lossy filter synthesis. This software obtains the coupling matrix of several network topologies for a given response and allows performing rotations on them to find the desired topology. Additionally, the software allows to evaluate the effect of loss in the networks resulting from the synthesis, even in those cases where the synthesis results in an ideal lossless network (i.e., classical and pre-distortion synthesis).
ChemInform Abstract: Synthetic Methods and Reactions. Part 176. Trimethylsilyl Iodide Catalyzed Reductive Coupling of Aldehydes (I) with Tertiary Alkoxytrimethylsilanes (II) to Crowded Unsymmetrical Ethers (III). (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Physical simulation of containment coupling with EMD and solid dam on thin strip continuous casting with twin rolls (2006)

A model for investigating the containment of molten metal puddle in a twin-roll caster with electromagnetic dam(EMD) coupled with a solid dam was established. The magnetic flux density distribution of electromagnetic field along the yoke surface was measured.The results show that EMD coupled with inside-ferromagnetodam is the best method among the electromagnetic field coupled with vinyl chloride dam,outside-ferromagnetodam,or without any solid dam,which can enhance the height of molten metal about 3.3 times than that without any solid dam.The containment height of molten metal increases linearly with increasing current.The fluctuation on the surface of molten metal was also analyzed.
Just-In-Time Classifiers for Recurrent Concepts (2013)

Just-in-time (JIT) classifiers operate in evolving environments by classifying instances and reacting to concept drift. In stationary conditions, a JIT classifier improves its accuracy over time by exploiting additional supervised information coming from the field. In nonstationary conditions, however, the classifier reacts as soon as concept drift is detected; the current classification setup is discarded and a suitable one activated to keep the accuracy high. We present a novel generation of JIT classifiers able to deal with recurrent concept drift by means of a practical formalization of the concept representation and the definition of a set of operators working on such representations. The concept-drift detection activity, which is crucial in promptly reacting to changes exactly when needed, is advanced by considering change-detection tests monitoring both inputs and classes distributions.
SHORT COMMUNICATION Archaeal Life on Tangkuban Perahu- Sampling and Culture Growth in Indonesian Laboratories (2012)

The aim of the expedition to Tangkuban Perahu, West Java was to obtain archaeal samples from the solfatara fields located in Domas crater. This was one of the places, where scientists from the University of Regensburg Germany had formerly isolated Indonesian archaea, especially Thermoplasma and Sulfolobus species but not fully characterized. We collected five samples from mud holes with temperatures from 57 to 88 oC and pH of 1.5-2. A portion of each sample was grown at the University of Regensburg in modified Allen’s medium at 80 oC. From four out of five samples enrichment cultures were obtained, autotrophically on elemental sulphur and heterotrophically on sulfur and yeast extract; electron micrographs are presented. In the laboratories of Universitas Indonesia the isolates were cultured at 55-60 oC in order to grow tetraetherlipid synthesizing archaea, both Thermoplasmatales and Sulfolobales. Here, we succeeded to culture the same type of archaeal cells, which had been cultured in Regensburg, probably a Sulfolobus species and in Freundt’s medium, Thermoplasma species. The harvested cells are documented by phase contrast microscope equipped with a digital camera. Our next steps will be to further
The Nonlinearity Coefficient - Predicting Overfitting in Deep Neural Networks. (2018)

For a long time, designing neural architectures that exhibit high performance was considered a dark art that required expert hand-tuning. One of the few well-known guidelines for architecture design is the avoidance of exploding gradients, though even this guideline has remained relatively vague and circumstantial. We introduce the nonlinearity coefficient (NLC), a measurement of the complexity of the function computed by a neural network that is based on the magnitude of the gradient. Via an extensive empirical study, we show that the NLC is a powerful predictor of test error and that attaining a right-sized NLC is essential for optimal performance. 
The NLC exhibits a range of intriguing and important properties. It is closely tied to the amount of information gained from computing a single network gradient. It is tied to the error incurred when replacing the nonlinearity operations in the network with linear operations. It is not susceptible to the confounders of multiplicative scaling, additive bias and layer width. It is stable from layer to layer. Hence, we argue that the NLC is the first robust predictor of overfitting in deep networks.
Separation devices based on forced coincidence response of fluid-filled pipes (1992)

A separation process based on the acoustic radiation force created in stationary fields produced by a forced coincidence excitation at ultrasonic frequencies of fluid-filled pipes has been developed. The efficacy of this method for the collection and manipulation of fine secondary phases in flowing suspensions will be compared to equivalent operations in stationary fields generated in acoustic interferometer chambers operated without coincidence effects. The basis for the axial translation of the phases concentrated at the pressure nodes to either end of the cell as a result of an applied periodic sweep in the driving frequency will be examined.
Peroxisome biogenesis and the formation of multivesicular peroxisomes during tombusvirus infection: a role for ESCRT?This review is one of a selection of papers published in the Special Issue on Plant Cell Biology. (2006)

Peroxisomes are highly dynamic organelles with regard to their metabolic functions, shapes, distribution, movements, and biogenesis. They are also important as sites for the development of some viral pathogens. It has long been known that certain members of the tombusvirus family recruit peroxisomes for viral RNA replication and that this process is accompanied by dramatic changes in peroxisome morphology, the most remarkable of which is the extensive inward vesiculation of the peroxisomal boundary membrane leading to the formation of a peroxisomal multivesicular body (pMVB). While it is unclear how the internal vesicles of a pMVB form, they appear to serve in effectively concentrating viral membrane-bound replication complexes and protecting nascent viral RNAs from host-cell defences. Here, we review briefly the biogenesis of peroxisomes and pMVBs and discuss recent studies that have begun to shed light on how components of the tombusvirus replicase exploit the molecular mechanisms involved in peroxisome membrane protein sorting. We also address the question of what controls invagination and vesicle formation at the peroxisomal membrane during pMVB biogenesis. We propose that tombusviruses exploit protein constituents of the class E vacuolar protein-sorting pathway referred to as ESCRT (endosomal sorting complex required for transport) in the formation of pMVBs. This new pMVB–ESCRT hypothesis reconciles current paradigms of pMVB biogenesis with the role of ESCRT in endosomal multivesicular body formation and the ability of enveloped RNA viruses, including HIV, to appropriate the ESCRT machinery to execute their budding programme from cells.
Human Transferrin Receptor Gene as a Marker Gene for MR Imaging (2001)

ETR+ tumors internalize the MR imaging probe through the action of transferrin receptor in amounts that can be detected with MR imaging.
CCR5Δ3259537-G/A Promoter Polymorphism Is Associated with Low Translational Efficiency and the Loss ofCCR5Δ32Protective Effects (2007)

We have recently demonstrated that the CCR5Delta32 protein interacts with CCR5 and CXCR4 and down-modulates their cell surface expression. We have also reported the absence of detectable expression of the truncated CCR5Delta32 protein in four out of six human immunodeficiency virus-infected (HIV(+)) CCR5(-/-) individuals. To explain the defect in protein expression in these samples, we cloned and sequenced the promoter regions of the six HIV(+) individuals. We have identified several polymorphisms in the CCR5Delta32 promoter region, but these polymorphisms were not associated with significant differences in mRNA levels. Coupled in vitro transcription/translation and polyribosome analysis demonstrated a strong association between a variant genotype designated CCR5Delta32 59537-A/A and a low translation efficiency. Protein analysis indicated that the peripheral blood mononuclear cells from two of the HIV(+) CCR5(-/-) individuals carrying the CCR5Delta32 59537-A/A variant expressed trace amounts of CCR5Delta32 protein compared to the individuals carrying the CCR5Delta32 59537-G/G genotype. The results imply that the absence of CCR5Delta32 protein in two HIV(+) individuals is due to a genetic defect in the translation of the protein. Together, these results highlight the importance of the CCR5Delta32 protein as an HIV suppressive factor and provide further insight into the mechanism of the protective effect of the CCR5Delta32 mutation.