gebhart/patrepeval huggingface dataset:
Effects of cell loss on the quality of service for MPEG video in ATM environment (2002)

In this paper, the impact of cell loss on the quality of service for MPEG video in ATM environment is investigated. It has been found that the consequence of the loss of video sequence header on picture quality can be tolerated even at a high cell loss ratio of 10/sup -3/. The loss of GOP and picture headers results in a picture loss ratio which is only slightly higher than the cell loss ratio due to the short lengths of those headers. The combined effect of GOP & picture header loss and slice loss, however, produces an errored picture ratio which renders the picture quality not easily accepted by the viewers, even if the cell loss ratio is maintained at a low level of 10/sup -6/. Thus, forward error correction schemes may be needed in the AAL to improve the picture quality expressed in terms of errored picture ratios.
A Mucosal Apposition Technique for Ureteroneocystostomy After Renal Transplantation in Cats (1996)

Renal transplantation is a successful treatment for terminal renal failure in cats. However, in the initial clinical study, there was a frequent occurrence of obstruction of the implanted ureter at the bladder wall or stoma. This resulted in the use of a modified "drop-in" technique that had proved effective in the prevention of obstruction in five normal cats. When applied to renal transplant recipients, ureteral obstruction was reduced, but continued to occur. The modified "drop-in" technique was abandoned and replaced with a technique that apposed the cut edge of the ureteral mucosa to the torn edge of the bladder mucosa. This technique is recommended as it has prevented ureteral obstruction in six successive cases. Prevention of ureteral obstruction, and the required corrective surgery, markedly reduces patient morbidity and mortality, length of hospitalization, and expense to the client.
Acquisition and rendering of transparent and refractive objects (2002)

This paper introduces a new image-based approach to capturing and modeling highly specular, transparent, or translucent objects. We have built a system for automatically acquiring high quality graphical models of objects that are extremely difficult to scan with traditional 3D scanners. The system consists of turntables, a set of cameras and lights, and monitors to project colored backdrops. We use multi-background matting techniques to acquire alpha and environment mattes of the object from multiple viewpoints. Using the alpha mattes we reconstruct an approximate 3D shape of the object. We use the environment mattes to compute a high-resolution surface reflectance field. We also acquire a low-resolution surface reflectance field using the overhead array of lights. Both surface reflectance fields are used to relight the objects and to place them into arbitrary environments. Our system is the first to acquire and render transparent and translucent 3D objects, such as a glass of beer, from arbitrary viewpoints under novel illumination.
Intensification of Ex Situ Bioremediation of Soils Polluted with Used Lubricant Oils: A Comparison of Biostimulation and Bioaugmentation with a Special Focus on the Type and Size of the Inoculum (2020)

Used lubricant oils (ULOs) strongly bind to soil particles and cause persistent pollution. In this study, soil microcosm experiments were conducted to model the <i>ex situ</i> bioremediation of a long term ULO-polluted area. Biostimulation and various inoculation levels of bioaugmentation were applied to determine the efficacy of total petrol hydrocarbon (TPH) removal. ULO-contaminated soil microcosms were monitored for microbial respiration, colony-forming units (CFUs) and TPH bioconversion. Biostimulation with inorganic nutrients was responsible for 22% of ULO removal after 40 days. Bioaugmentation using two hydrocarbon-degrader strains: <i>Rhodococcus quingshengii</i> KAG C and <i>Rhodococcus erythropolis</i> PR4 at a small inoculum size (10<sup>7</sup> CFUs g<sup>-1</sup> soil), reduced initial TPH concentration by 24% and 29%, respectively; the application of a higher inoculum size (10<sup>9</sup> CFUs g<sup>-1</sup> soil) led to 41% and 32% bioconversion, respectively. After 20 days, all augmented CFUs decreased to the same level as measured in the biostimulated cases, substantiating the challenge for the newly introduced hydrocarbon-degrading strains to cope with environmental stressors. Our results not only highlight that an increased number of degrader cells does not always correlate with enhanced TPH bioconversion, but they also indicate that biostimulation might be an economical solution to promote ULO biodegradation in long term contaminated soils.
Influence of the transducer geometry on the phase of the signal used for reducing second harmonic during ultrasound propagation (2008)

Ultrasound contrast harmonic imaging is one of the most used contrast detection method in common system used for diagnostic. Its success comes from the higher non linearity properties of ultrasound contrast agents compared to tissue. A way to further enhance agent to tissue ratio would be to locally suppress second harmonic that is generated due to non linear propagation in tissue. Reducing higher harmonics from surrounding medium is a challenge that has been previously studied. Christopher proposed to transmit inverted replica of back propagated signal, Krishnan, back propagated only second harmonic and added inverted replica of it to excitation, Shen proposed transmitting third harmonic to reduce the second harmonic. In our study, a custom made dual frequency phased array transducer, is used to transmit 2 different signals: the imaging signal and the Second Harmonic Reduction Signal (SHRS). In this paper we study the what is optimal phase Phi <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">SHRS</sub> <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> of SHRS needed to achieve a maximum 2 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">nd</sup> harmonic frequency reduction in a region of interest, depending upon the several properties of transducer apertures.We have observed that as the size of the transducer and focal distance changes, also the optimal phase of the signal used for reducing the 2 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">nd</sup> harmonic changes. If the phase of the signal is inappropriate, increase of the 2 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">nd</sup> harmonic can be observed rather than decrease.
850 nm hybrid vertical cavity laser integration for on-chip silicon photonics light sources (2017)

The realization of 850 nm hybrid III-V/dielectric VCSELs is reported in order to realize low power consumption integrated light sources for SiN waveguide circuits, which find applications both in short-reach optical communication and optical sensors.
Design and Test of a Superconducting Magnetic Energy Storage (SMES) Coil (2010)

This paper presents an SMES coil which has been designed and tested by University of Cambridge. The design gives the maximum stored energy in the coil which has been wound by a certain length of second-generation high-temperature superconductors (2G HTS). A numerical model has been developed to analyse the current density and magnetic field distribution and calculate the AC losses during the charge and discharge process of the coil. A cryostat has been designed and a test of the I-V curve measurement of the coil has been accomplished. In addition, the power electronics control of the SMES coil has been simulated.
Vasodilator treatment with hydralazine increases blood flow in mdx mice resistance arteries without vascular wall remodelling or endothelium function improvement (2005)

This study provides functional evidence that local blood flow could be improve by hydralazine in mdx mice despite a lack of vascular adaptation to flow. This study brings a new insight in the pathophysiology of dystrophin-related myopathies. Nevertheless, the consequences of an increased blood flow in non-adapted arteries remain unknown.
Synthesis of the Butatriene C4 Function: Methodology and Applications (2011)

International audience
Pudalovet al.Reply: (2004)

A Reply to the Comment by S. Das Sarma and E. H. Hwang.Received 6 April 2004DOI:https://doi.org/10.1103/PhysRevLett.93.269704
Development of a GalNAc-Tyrosine-Specific Monoclonal Antibody and Detection of Tyrosine O-GalNAcylation in Numerous Human Tissues and Cell Lines (2022)

Glycosylation is a vital post-translational modification involved in a range of biological processes including protein folding, signaling, and cell-cell interactions. In 2011, a new type of <i>O</i>-linked glycosylation was discovered, wherein the side-chain oxygen of tyrosine is modified with a GalNAc residue (GalNAc-Tyr). At present, very little is known about GalNAc-Tyr prevalence, function, or biosynthesis. Herein, we describe the design and synthesis of a GalNAc-Tyr-derived hapten and its use in generating a GalNAc-Tyr selective monoclonal antibody. The antibody, G10C, has an unusually high affinity (app <i>K</i><sub>D</sub> = 100 pM) and excellent selectivity for GalNAc-Tyr. We also obtained a crystal structure of the G10C Fab region in complex with 4-nitrophenyl-<i>N</i>-acetyl-α-d-galactosaminide (a small molecule mimic of GalNAc-Tyr) providing insights into the structural basis for high affinity and selectivity. Using this antibody, we discovered that GalNAc-Tyr is widely expressed in most human tissues, indicating that it is a ubiquitous and underappreciated post-translational modification. Localization to specific cell types and organ substructures within those tissues indicates that GalNAc-Tyr is likely regulated in a cell-specific manner. GalNAc-Tyr was also observed in a variety of cell lines and primary cells but was only present on the external cell surface in certain cancer cell lines, suggesting that GalNAc-Tyr localization may be altered in cancer cells. Collectively, the results shed new light on this under-studied form of glycosylation and provide access to new tools that will enable expanded biochemical and clinical investigations.
Opportunities for High Wind Energy Penetration (1997)

Wind power is today a mature technology, which at windy locations, is economically competitive to conventional power generation technologies. This and growing global environmental concerns have led governments to encourage and plan for wind energy development, a typical aim being 10% of electricity consumption. The successful operation of the three major power systems of Cape Verde, with a total wind energy penetration of about 15% since December 1994, demonstrates that power systems can be operated with high penetration of wind energy by adding simple control and monitoring systems only. Thorough analyses conclude that expanding to even above 15% wind energy penetration in the Cape Verde power systems is economical Worldwide, numerous locations with favorable wind conditions and power systems similar to the Capeverdean provide good opportunities for installing wind farms and achieving high wind energy penetration.
Are Radiology Technologists Satisfied with Their Work? A Cross-Sectional Study from Taif Hospitals (2020)

Background: Job satisfaction can affect workers’ behaviour, thereby influencing organisational performance. Workers with low levels of job satisfaction have negative attitudes toward their jobs and may cause depression and anxiety. Purpose: The main aim of this study is to measure the overall job satisfaction among radiographers in Taif city. Methods: This study used the Minnesota Scoring Questionnaire to measure job satisfaction. The data collection was conducted between September 2018 and April 2019 in all major hospitals in Taif. Results: This study revealed that the overall job satisfaction of radiographers was moderate. It is, however, higher among radiographers in armed forces hospitals compared with their counterparts in the Ministry of Health hospitals. The job satisfaction of male radiographers was greater than their female peers. Finally, job satisfaction was high in those who work in advanced modality departments. Conclusion: Job satisfaction is critical for healthcare workers. This study indicated that job satisfaction is moderate for radiographers in Taif hospitals. Factors affecting their satisfaction include the feel of independence and recognition.
Spatial Vision-Based Control of High-Speed Robot Arms (2006)

Industrial robots are known to execute given programs at high speed and at the same time with high repeatability. From non industrial scenarios as in (Nakabo et al., 2005) or (Ginhoux et al., 2004) we know that cameras can be used to execute high-speed motion even in those cases in which the desired path is not a priori given but online sensed. In general, such visual tracking tasks of following a randomly moving target by a camera are not accurate enough for industrial applications. But there the work-piece will scarcely move randomly. So in this chapter we concentrate on another type of visual ser-voing, in which the path that has to be followed is fixed in advance, but not given by a robot program. A robot-mounted camera is a universal sensor which is able to sense poses with high accuracy of typically less than a millimeter in the close-up range. At the same time with high shutter speed the robot may move fast, e.g. at 1 m/s. In contrast to expensive high-speed cameras, yielding a high frame rate of e.g. 1 kHz as in (Nakabo et al., 2005), we restrict on a standard CCIR camera, to meet the requirements of a cost-effective hardware. Off-the-shelf cameras are fundamental for the acceptance in industry. So an important feature of our method is an appropriate control architecture that tolerates low sampling rates of sensors. The camera is mounted at the robot arm and measures the work-piece pose (given by boundary lines) with respect to the tool center point (tcp) of the robot. More precisely, the camera is mounted laterally to provide enough space for a tool. So with constant moving sense we have a predictive sensor as in (Meta-Scout, 2006). With alternating moving sense the camera has to be tilted so that the corresponding nominal line point
Non-exhaustive search methods and their use in the minimization of Reed-Muller canonical expansions (1996)

Abstract A number of non-exhaustive search algorithms are presented. The methods are a 'classical' genetic algorithm, a tabu search, an evolutionary strategy and stochastically repeated nearest and steepest-ascent hill-climbing algorithms. They are then used to determine optimum and good polarities for Reed-Muller canonical expansions of Boolean functions, and comparisons are drawn between the relative e effectiveness of each method. Tabu search and nearest-ascent hill-climbers are found to be particularly appropriate for these problems.
The alternative carboxyl termini of avian cardiac and brain sarcoplasmic reticulum/endoplasmic reticulum Ca(2+)-ATPases are on opposite sides of the membrane. (1992)

The sarcoplasmic/endoplasmic reticulum slow-twitch or cardiac Ca(2+)-ATPase (SERCA2) is expressed as two forms (SERCA2a and SERCA2b) which vary at their extreme carboxyl termini. SERCA2a and SERCA2b are derived from alternatively spliced primary transcripts of the same gene. These two alternative carboxyl termini are highly conserved in mammals (Eggermont, J. A., Wuytack, F., De Jaegere, S., Nelles, L., and Casteels, R. (1989) Biochem. J. 260, 757-761; Lytton, J., and MacLennan, D. H. (1988) J. Biol. Chem. 263, 15024-15031) and birds (Campbell, A. M., Kessler, P. D., Sagara, Y., Inesi, G., and Fambrough, D. M. (1991) J. Biol. Chem. 266, 16050-16055). The topology of SERCA2a is believed to be identical to the fast-twitch Ca(2+)-ATPase (SERCA1) with 10 membrane-spanning domains. Based on hydropathy analysis, the extended carboxyl terminus of SERCA2b is predicted to span the endoplasmic reticulum (ER) membrane an additional (i.e. 11th) time. We have added the human c-myc epitope, a 10-amino acid sequence recognized by monoclonal antibody 9E10, onto the carboxyl termini of SERCA2a and SERCA2b to test whether or not their carboxyl termini are on the same side of the ER membrane. The added epitopes do not appear to disrupt topology as judged from unaltered Ca2+ transport. Immunocytochemical studies demonstrate that SERCA2a and SERCA2b have their carboxyl termini on opposite sides of the ER membrane; SERCA2a's is in the cytosol and SERCA2b's is in the ER lumen.
Data from A Phase I Trial of Regional Mesothelin-Targeted CAR T-cell Therapy in Patients with Malignant Pleural Disease, in Combination with the Anti–PD-1 Agent Pembrolizumab (2023)

&lt;div&gt;Abstract&lt;p&gt;Malignant pleural diseases, comprising metastatic lung and breast cancers and malignant pleural mesothelioma (MPM), are aggressive solid tumors with poor therapeutic response. We developed and conducted a first-in-human, phase I study of regionally delivered, autologous, mesothelin-targeted chimeric antigen receptor (CAR) T-cell therapy. Intrapleural administration of 0.3M to 60M CAR T cells/kg in 27 patients (25 with MPM) was safe and well tolerated. CAR T cells were detected in peripheral blood for &gt;100 days in 39% of patients. Following our demonstration that PD-1 blockade enhances CAR T-cell function in mice, 18 patients with MPM also received pembrolizumab safely. Among those patients, median overall survival from CAR T-cell infusion was 23.9 months (1-year overall survival, 83%). Stable disease was sustained for ≥6 months in 8 patients; 2 exhibited complete metabolic response on PET scan. Combination immunotherapy with CAR T cells and PD-1 blockade agents should be further evaluated in patients with solid tumors.&lt;/p&gt;Significance:&lt;p&gt;Regional delivery of mesothelin-targeted CAR T-cell therapy followed by pembrolizumab administration is feasible, safe, and demonstrates evidence of antitumor efficacy in patients with malignant pleural diseases. Our data support the investigation of combination immunotherapy with CAR T cells and PD-1 blockade agents in solid tumors.&lt;/p&gt;&lt;p&gt;&lt;i&gt;See related commentary by Aldea et al., p. 2674&lt;/i&gt;.&lt;/p&gt;&lt;p&gt;&lt;i&gt;This article is highlighted in the In This Issue feature, p. 2659&lt;/i&gt;&lt;/p&gt;&lt;/div&gt;
The University of Tokyo Atacama Observatory 6.5m telescope: On-sky performance evaluations of the mid-infrared instrument MIMIZUKU on the Subaru telescope (2020)

The Mid-Infrared Multi-field Imager for gaZing at the UnKnown Universe (MIMIZUKU) is developed as the first-generation mid-infrared instrument for the University of Tokyo Atacama Observatory (TAO) 6.5-m telescope. MIMIZUKU performs medium-band imaging and low-resolution spectroscopy in 2-38 microns and enables highest-spatial-resolution observations in the long-wavelength mid-infrared beyond 25 microns. In addition, MIMIZUKU has a unique opto-mechanical device called ‘Field Stacker’, which enables us to observe a distant (&lt;25 arcminutes) pair of target and reference objects simultaneously and improves accuracy of atmospheric calibration. This function is expected to improve photometric accuracy and quality of spectroscopic data even in the long-wavelength mid-infrared regions, where the atmospheric absorption is severe. In 2018, engineering observations of MIMIZUKU were carried out at the Subaru telescope, and its first-light was successfully achieved. In the engineering observations, the imaging and spectroscopic functions in the mid-infrared wavelengths (7.6-25 microns) were confirmed to be working almost as expected, although the sensitivity is still worse than the background-limited performance by a factor of a few due to high readout noise. The Field Stacker was also confirmed to be working as expected. It is confirmed that the photometric instability can be reduced to a few percent by using Field Stacker even when the atmospheric transmittance varies by 10% in time. It is also confirmed that spectroscopic observations can be performed not only in 10-micron band but also in 20-micron band, where the spectroscopic observations are difficult even at the Mauna Kea site. We report the results of these on-sky performance evaluations.
AAAI 2002 Workshops (2002)

The Association for the Advancement of Artificial Intelligence (AAAI) presented the AAAI-02 Workshop Program on Sunday and Monday, 28-29 July 2002 at the Shaw Convention Center in Edmonton, Alberta, Canada. The AAAI-02 workshop program included 18 workshops covering a wide range of topics in AI. The workshops were Agent-Based Technologies for B2B Electronic-Commerce; Automation as a Caregiver: The Role of Intelligent Technology in Elder Care; Autonomy, Delegation, and Control: From Interagent to Groups; Coalition Formation in Dynamic Multiagent Environments; Cognitive Robotics; Game-Theoretic and Decision-Theoretic Agents; Intelligent Service Integration; Intelligent Situation-Aware Media and Presentations; Meaning Negotiation; Multiagent Modeling and Simulation of Economic Systems; Ontologies and the Semantic Web; Planning with and for Multiagent Systems; Preferences in AI and CP: Symbolic Approaches; Probabilistic Approaches in Search; Real-Time Decision Support and Diagnosis Systems; Semantic Web Meets Language Resources; and Spatial and Temporal Reasoning.
The Lysine-specific Demethylase 1 Is Required for Cell Proliferation in Both p53-dependent and -independent Manners (2007)

The lysine-specific demethylase 1 (LSD1), a component of several histone deacetylase complexes, plays an important role in chromatin remodeling and transcriptional regulation. Here, we generated multiple cell lines in which LSD1 is inducibly expressed or knocked down and found that LSD1 is required for cell proliferation. In addition, we found that deficiency in LSD1 leads to a partial cell cycle arrest in G(2)/M and sensitizes cells to growth suppression induced by DNA damage or MDM2 inhibition in a p53-dependent manner. We also showed that LSD1 deficiency delays p53 stabilization induced by DNA damage, leading to a delayed induction of p21 and MDM2. Finally, we performed a microarray study and identified several novel LSD1 target genes, including S100A8, which encodes a calcium-binding protein, and DEK, a proto-oncogene. Taken together, we uncovered that LSD1 has a pro-oncogenic function by modulating pro-survival gene expression and p53 transcriptional activity.
Effect of bisacodyl on gut lavage cleansing for colonoscopy. (1987)

The effect of 10 mg oral bisacodyl (n = 19) or placebo (n = 26) on colon cleansing with polyethylene glycol electrolyte lavage solution was studied during colonoscopy. Patient tolerance was evaluated by questionnaire. During colonoscopy endoscopists graded adequacy of cleansing and subjective amounts of residual fluid and recorded the actual amount of fluid suctioned. Patient tolerance and adequacy of cleansing were not different between bisacodyl and placebo. There was no difference in subjective and measured residual fluid between the two groups. Compared to placebo, 10 mg oral bisacodyl does not influence adequacy of cleansing, patient tolerance, or residual fluid following polyethylene glycol electrolyte lavage solution for colonoscopy. This suggests that the beneficial cleansing effects with bisacodyl for barium enema may occur by mechanisms other than simple fluid evacuation.