gebhart/patrepeval huggingface dataset:
The effect of magnetization transfer on functional MRI signals (1997)

A magnetization transfer (MT)-prepared echo-planar imaging (EPI) pulse sequence was developed to study motor cortex activation, using a finger tapping paradigm. MT weighting resulted in a reduction of both the activated area and, in the majority of activated pixels, the functional MRI signal, regardless of the correlation coefficient threshold used in generating the activation map. The magnetization transfer ratio (MTR) was higher during task activation than during rest. Because the MT effect is strongly tissue-dependent, these results support the hypothesis that incorporation of MT into functional MRI will help to understand the origin of the functional MRI signal.
Non-rigid registration of cardiac MR: application to motion modelling and atlas-based segmentation (2003)

Three-dimensional (3D) and four-dimensional (4D) imaging of the heart is a rapidly developing area of research in medical imaging. Recent advances in development of MR imaging for fast spatio-temporal cardiac imaging have led to an increased interest in the use of MR imaging for functional analysis of the cardiovascular system. Segmentation of left and right ventricle and modelling of myocardial motion provide important information for quantitative functional analysis. In this paper we show how non-rigid registration techniques can be used to solve these problems in cardiac MR images.
Ethylbenzene removal under mesophilic conditions in a multiple-stage biofilter with macadamia nutshells as carrier material (2011)

A biofilter was used to treat air polluted with ethylbenzene. Macadamia nutshells, which are a cheap waste product in Thailand, were chosen as the packing material for the biofilter. The moisture content (6.6 w%), water holding capacity (16.8 w%), nutshell density (1.3 g ml-1) and organic content (78.0 w%) of the macadamia nutshell were measured. The biofilter was operated during 5 months, in which several inlet loads (IL), empty bed residence times (EBRT) and temperatures (T) were applied. At a T of 303 ± 2 K removal efficiencies (RE) higher than 90 % were obtained for IL lower than 95 g m-3 h-1 and 85 g m-3 h-1 at EBRTs of 150 and 90 s, respectively. The estimated yield coefficient, determined from the carbon dioxide production, resulted in 0.79 g dry biomass per g of ethylbenzene (EB) degraded. The results illustrate that a biofilter with macadamia nutshells as carrier material is a good option for air treatment at temperatures from 298 to 308 K. In the mesophilic area, the performance of the biofilter will higher with a higher temperature.
Neutron Stimulated Emission Computed Tomography (NSECT) for Early Detection of Breast Cancer (2006)

Neutron stimulated emission computed tomography (NSECT) is being developed as a non-invasive spectroscopic technique to determine element concentrations in the human body. We have implemented an NSECT system that uses a beam of high-energy neutrons to identify element concentrations in tissue and create 2-dimensional maps of elemental distribution through a single non-invasive tomographic scan. Neutrons scatter inelastically with atomic nuclei in tissue, causing them to emit characteristic gamma photons. These gamma photons are detected and identified using an energy-sensitive gamma detector. By measuring the energy and number of emitted gamma photons, the system can determine the elemental composition of the target tissue. NSECT has the advantage of being able to detect breast cancer at very early stages compared to anatomic screening techniques, as it detects changes in trace element concentrations in the breast, which usually occur before anatomical features such as tumors and micro-calcifications appear. The tomographic scanning system eliminates the need for breast compression and patient disrobing. The system design can be made portable by using a commercially available portable neutron source with a gamma detector. From our preliminary results, NSECT shows significant promise in early diagnosis of breast cancer. It has the potential to evolve into an easily accessible screening modality and diagnostic technique for breast cancer, which can detect and identify malignant tissue in the breast and generate a two-dimensional image through a single non-invasive tomographic scan. Patient dose levels from NSECT are comparable to those of screening mammography. Efforts are under way to achieve the micro-gram sensitivity required for in-vivo trace element detection in the breast at the lowest possible patient dose levels. Our final goal is to implement a portable, low-dose tomographic screening system for breast cancer which does not require breast compression or invasive biopsies.
Memory allocation for low-power real-time embedded microcontroller: a case study (2022)

Memory allocation of instructions and data can affect the program execution speed. This paper tests various memory-intensive benchmarks under different memory allocations on a Cortex-M4-based microcontroller and solves the allocation problem using integer linear programming.
Bayesian Wideband Spectrum Segmentation for Cognitive Radios (2009)

A novel approach for wideband spectrum segmentation is proposed. The proposed method, called segmented periodogram, is based on the posterior expectation of the piece-wise flat realizations of the underlying signal spectrum, which is obtained through the simulated samples drawn from the joint posterior using the reversible jump Markov chain Monte Carlo (RJMCMC) technique. The segmented periodogram is a coarse description of the spectrum, which can be further utilized to obtain desired spectral parameters. The proposed framework is suitable for cognitive radios (CRs) as it allows the use of knowledge built from past experiences in the form of marginal densities as prior initializations in future calculations.
High power low non-linearity Erbium Ytterbium co-doped fiber amplifier pumped by wavelength-multiplexed high power 1480 nm laser diodes (2000)

We demonstrate that an Erbium Ytterbium co-doped fiber amplifier pumped at 1480 nm has high efficiency and very low non-linearity. We used only eight pump lasers and achieved more than 30 dB gain and 760 mW total output of eight channels without generating any significant four-wave mixing.
Genetic analysis of conservation and variation of lipooligosaccharide expression in two L8-immunotype strains of Neisseria meningitidis (2001)

Neisseria meningitidis strains A1 and M978 both express the lipooligosaccharide (LOS) L8 immunotype [Gu et al., J. Clin. Microbiol. 30 (1992) 2047–2053]. Under different growth conditions, strain A1 did not change its LOS profile whereas strain M978 produced variable LOS profiles on SDS–PAGE. To understand the genetic basis of LOS conservation and variation, their lgt locus encoding glycosyltransferases responsible for the biosynthesis of the α-chain of LOS was analyzed. Strain A1 possessed only two genes, lgtA and lgtH, at the lgt locus. The lgtA gene was inactivated due to a frameshift mutation; thus strain A1 expressed only L8 LOS. In contrast, strain M978 contained five genes lgtZ, lgtC, lgtA, lgtB and lgtE at this locus, thus it had a potential to express L1, L3,7 in addition to the L8 LOS. The data showed that strain A1 is a better reference strain for the L8 immunotype because of the stability of L8 LOS expression resulting from its unique lgt locus. In addition, these two strains had two new genetic organizations, lgtAH and lgtZCABE, compared to the reported gene organization at the lgt locus in N. meningitidis.
Improving Storage Performance with Non-Volatile Memory-based Caching Systems (2017)

University of Minnesota Ph.D. dissertation. April 2017. Major: Computer Science. Advisor: David Du. 1 computer file (PDF); ix, 104 pages.
Extraction of metal ions with N,N-disubstituted amides (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTExtraction of metal ions with N,N-disubstituted amidesJames S. Fritz and Gene M. OrfCite this: Anal. Chem. 1975, 47, 12, 2043–2045Publication Date (Print):October 1, 1975Publication History Published online1 May 2002Published inissue 1 October 1975https://pubs.acs.org/doi/10.1021/ac60362a008https://doi.org/10.1021/ac60362a008research-articleACS PublicationsRequest reuse permissionsArticle Views188Altmetric-Citations34LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Importance of Surfactant Quantity and Quality on Growth Regime of Iron Oxide Nanoparticles (2020)

This study shows the influence of selected nonstandard surfactants on the growth and properties of magnetite nanoparticles. Particles were obtained using thermally decomposed iron (III) acetylacetonate in an organic environment. For synthesis, three different concentrations (4, 8, and 16 mmol) of tested surfactants were used. Five types of each long-chain carboxylic acid and amines were selected for stabilization of nanoparticles. Nanoparticles were characterized by X-ray diffraction, transmission electron microscopy, and infrared spectroscopy. Magnetic properties of the nanoparticles were tested by conventional room temperature Mössbauer spectroscopy with and without external magnetic field. TEM images clearly showed that application of tertiary amines causes the nanoparticles to form nanoflowers, in contrast to other compounds, which do not show such growth. Influence of surfactant amount on growth regime depends on the nature of the substances. Mössbauer spectroscopy confirms differences in magnetic core composition as a result of the surfactant amount present in synthetic procedure.
Interferences in the chemiluminescent measurement of NO and NO2 emissions from combustion systems (1976)

Two factors which may affect the quantification of NO and NO2 concentrations when using chemiluminescent analysis are investigated. The first is the dependence of the chemiluminescent intensity on competing third body quenching reactions. Relative quenching efficiencies are determined as a function of third body concentration for six different species which are common products of combustion. A mathematical expression is derived which allows calculation of the actual concentration of NO given the indicated concentration of NO and the concentrations of the important third bodies. An example calculation is presented. The second factor which is investigated involves the conversion of low molecular weight nitrogen containing species, other than NO2, in commercial NOx converters. Conversion efficiencies for six species were determined using a commercial stainless steel catalyst at 923 K.
Laser annealing study of the grain size effect in polycrystalline silicon Schottky diodes (1982)

Laser annealing is used to controllably vary the grain size of polycrystalline silicon films. The properties of Schottky diodes formed in such layers are studied experimentally by I-V and C-V measurements and interpreted in the framework of the grain boundary trapping model for polycrystalline silicon. For large grained material (grain size ≊10 μm) nearly ideal Schottky diode characteristics with a diode factor n close to unity are found. As deposited, fine grained material is fully depleted at the doping levels employed and yields a p-i-n diode behavior characterized by n=2. Observation of this regime without series resistance limitations is possible by using a buried n+ layer as the back contact of the diodes. Reverse currents of the diodes are inversely proportional to the grain size, as expected for generation at grain boundary traps.
Book Reviews (1988)

This book is a thorough and detailed text on the optical design of astronomical telescopes.
Nonequilibrium distribution at finite noise intensity (2003)

The non-equilibrium distribution in dissipative dynamical systems with unstable limit cycle is analyzed in the next-to-leading order of the small-noise approximation of the Fokker-Planck equation. The noise-induced variations of the non-equilibrium distribution are described in terms of topological changes in the pattern of optimal paths. It is predicted that singularities in the pattern of optimal paths are shifted and cross the basin boundary in the presence of finite noise. As a result the probability distribution oscillates at the basin boundary. Theoretical predictions are in good agreement with the results of numerical solution of the Fokker-Planck equation and Monte Carlo simulations.
Biomaterials (2014)

Explores Biomedical Science from a Unique PerspectiveBiomaterials: A Basic Introduction is a definitive resource for students entering biomedical or bioengineering disciplines. This text offers a detailed exploration of engineering and materials science, and examines the boundary and relationship between the two. Based on the author's course lectur
Cloning, characterization, and functional expression of cDNAs encoding glucose transporter proteins from the human parasite Schistosoma mansoni. (1994)

The blood-dwelling adult form of the parasitic worm, Schistosoma mansoni, consumes prodigious quantities of host glucose following its transport across the tegument. Immunologic or pharmacologic targeting of the relevant transporter proteins might form the basis of a schistosome control strategy. Here we report the isolation and characterization of three different full-length cDNAs whose predicted protein sequences show a high degree of sequence and structural similarity to the facilitated diffusion transporter proteins of other animals, plants, and bacteria. Functional expression of two cDNAs has been achieved by injection of Xenopus oocytes with in vitro derived sense strand RNA. Injected oocytes have a significantly increased ability to take up radiolabeled glucose analogues over controls. S. mansoni glucose transporters expressed in oocytes exhibit stereospecificity for D-glucose, have relaxed specificity for different hexoses, exhibit sodium independence, and are markedly inhibited by phloretin and cytochalasin B. These two transporters, expressed in oocytes, have a Km for 3-O-methylglucose of 1.3 and 2 mM. A third glucose transporter homologue cDNA appears to derive from a recent pseudogene. Both of the functional S. mansoni glucose transporter genes are expressed in larval and adult male and female schistosomes.
A generalized graphical model to specify A/D resolution from receiver front-end (2012)

The conventional way to define the specifications of each block in the wireless receiver (RX) chain is budget link. It excludes the analog baseband and analog-to-digital converter (ADC) generally. Based on the budget link methodology, this paper presents a new generalized graphical model (GGM) to analyze the specifications of ADC on both noise and linearity aspects, which also establish a bridge between wireless standard and hardware performance estimation. Using such method, the ADC's requirement could be optimized from the wireless receiver (RF) front end. Meanwhile it enables the trade-off between the RF and ADC. The ADC's main specifications such as signal-to-noise ratio (SNR) and signal-to-distortion ratio (SDR) are emphasized in this paper. The demonstrated capability of this method is illustrated by deriving the main specifications of a Bluetooth receiver.
Differential 9-cis-Retinoic Acid-dependent Transcriptional Activation by Murine Retinoid X Receptor α (RXRα) and RXRβ (1996)

The 9-cis-retinoic acid (9cRA)-inducible enhancer of the rat cellular retinol-binding protein type II gene (CRBP II) was shown to be differentially regulated by the murine retinoid X receptor alpha (RXR alpha) as compared with RXR beta. Transient transfection assays performed in NIH 3T3 fibroblast cells demonstrated that RXR alpha yielded a high level of 9cRA-dependent transcription of a reporter gene linked to the CRBP II enhancer, when compared with RXR beta. This effect was cell type-dependent, since both receptors elicited comparable transcriptional activation of the same reporter in P19 embryonal carcinoma cells. To further explore the structural determinants responsible for the differences between these two receptors, a series of chimeric receptor constructs were made. Co-transfection assays utilizing these chimeras demonstrated that both the N terminus and the hinge region connecting the DNA binding domain with the ligand binding domain of RXR alpha were responsible for the high level of 9cRA-dependent transcription observed in NIH 3T3 cells, Furthermore, the hinge region of RXR alpha was shown to be necessary to repress, in the absence of hormone, the transcriptional activation function located in the N-terminal domain of RXR alpha. These results stress the importance of functional links between different RXR domains and suggest an RXR subtype and cell type-dependent specificity in the control of the 9cRA response.
Characterization of an E1A-CBP Interaction Defines a Novel Transcriptional Adapter Motif (TRAM) in CBP/p300 (1999)

The adenovirus E1A protein subverts cellular processes to induce mitotic activity in quiescent cells. Important targets of E1A include members of the transcriptional adapter family containing CBP/p300. Competition for CBP/p300 binding by various cellular transcription factors has been suggested as a means of integrating different signalling pathways and may also represent a potential mechanism by which E1A manipulates cell fate. Here we describe the characterization of the interaction between E1A and the C/H3 region of CBP. We define a novel conserved 12-residue transcriptional adapter motif (TRAM) within CBP/p300 that represents the binding site for both E1A and numerous cellular transcription factors. We also identify a sequence (FPESLIL) within adenovirus E1A that is required to bind the CBP TRAM. Furthermore, an E1A peptide containing the FPESLIL sequence is capable of preventing the interaction between CBP and TRAM-binding transcription factors, such as p53, E2F, and TFIIB, thus providing a molecular model for E1A action. As an in vivo demonstration of this model, we used a small region of CBP containing a functional TRAM that can bind to the p53 protein. The CBP TRAM binds p53 sequences targeted by the cellular regulator MDM2, and we demonstrate that an MDM2-p53 interaction can be disrupted by the CBP TRAM, leading to stabilization of cellular p53 levels and the activation of p53-dependent transcription. Transcriptional activation of p53 by the CBP TRAM is abolished by wild-type E1A but not by a CBP-binding-deficient E1A mutant.
Das geschriebene und das mündliche Evangelium (1961)

(Vorlesung, gehalten auf dem 1. Pastoralkolleg des Bundes der Synoden vom 18. 7. — 21. 7. 1961 in Sao Leopoldo).
Intracellular protein catabolism: evidence for sequestration of proteins into an intermediate-filament fraction before lysosomal degradation. (1986)

Iodinated [125I] glycolytic enzymes (lactate dehydrogenase, pyruvate kinase and glyceraldehyde phosphate dehydrogenase) and bovine serum albumin have been erythrocyte microinjected or scrape loaded into confluent 3T3-L1 cells. The glycolytic enzymes are rapidly (within 30 min) sequestered into a form which is inextractable with sequential treatments with digitonin, Triton X-100 and potassium iodide. Bovine serum albumin is readily extractable by digitonin. Glycolytic enzymes are degraded relatively slowly (t1/2's 124-330 h) by a lysosomal mechanism inhibitable by NH4Cl (50-91%), 3-methyl adenine (62-70%) and leupeptin (47-80%). Bovine serum albumin is degraded relatively rapidly (t1/2 17-20 h) by a non-lysosomal mechanism. Nycodenz density gradient fractionation of homogenates of 3T3-L1 cells after microinjection shows that [125I]-lactate dehydrogenase sediments in a dense fraction containing nuclei (DNA) and lacking cytosolic, lysosomal, plasma membrane or mitochondrial marker enzymes. The [125I]-enzyme is not released from this fraction by the sequential detergent/salt fractionation described above. Analysis of the detergent/salt inextractable residue by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulphate and 2-mercaptoethanol shows nuclear histones and vimentin. [125I]-lactate dehydrogenase does not enter the polyacrylamide gel in the absence of 2-mercaptoethanol. Importantly endogenous proteins are found in the residue in the presence of leupeptin. The data suggest that sequestration of proteins into a nuclear-intermediate filament fraction may precede lysosomal degradation. Iodinated [125]-Sendai virus HN and F membrane glycoproteins in reconstituted Sendai virus envelope (RSVE) have been fused with growing HTC cells. HN and F are rapidly internalised (within 5 h) to assume a perinuclear distribution before lysosomal degradation. HN and F proteins are either extractable predominantly with triton X-100 or are inextractable by the treatments described above. Nycodenz fractionation of HTC cell homogenates after RSVE-cell fusion shows that HN and F sediment predominantly as a dense peak, enriched in DNA and free from the markers indicated above, and a less dense peak enriched in lysosomal marker enzymes. HN and F proteins translocate from the dense to the less dense peak and are degraded lysosomally (t1/2 av. 70 h). Leupeptin slows the translocation. The detergent/salt inextractable residue is enriched in nuclear histones and vimentin. The data suggest that Sendai viral membrane glycoproteins are sequestered into a nuclear-intermediate filament fraction before lysosomal degradation.(ABSTRACT TRUNCATED AT 400 WORDS)
Controlling the Degree of Esterification of Citrus Pectin for Demanding Applications by Selection of the Source (2017)

Analyzed by a quantitative method based on diffuse reflectance infrared Fourier transform spectroscopy, pectins extracted from different regions (outer skin, peel, and waste) of citrus fruits (red orange, lemon, and grapefruit) via microwave-assisted hydrodiffusion show significant variations. All polymers obtained are low-methoxyl pectins, with high contents in galacturonic acid regions. The degree of esterification (DE) of pectin extracted from different regions increases in the order waste < peel < outer skin for red orange, inverting for lemon. Thus, the pectins with the lowest DE are those extracted from red orange waste and lemon outer skin (∼25%). These findings open the route to nutraceutical- and pharmaceutical-grade pectins from citrus, in which the source fruit and its regions may be chosen, according to the desired DE.