gebhart/patrepeval huggingface dataset:
Non-analytic object recognition using the Hough transform with the matching technique (1994)

By using the combination of the Hough and the contour sequence matching techniques, the authors suggest a new algorithm of scale and rotation invariant for pattern recognition. In the proposed algorithm, the conventional four-dimensional Hough space is replaced by a two-dimensional one. Because of the significant reduction of memory requirement, the authors can provide a much faster and more efficient generalised Hough algorithm. In order to enhance the performance of the Hough transform, they also suggest a new peak searching technique on the Hough space to achieve an accurate location of the detected objects.
Carcinogenesis in rats by substituted dialkylnitrosamines given by gavage. (1992)

A number of nitrosamines that have been studied by administration to rats as solutions in drinking water have been examined by gavage administration of similar doses, for assessment of the role of pharmacokinetics in organ-specific carcinogenesis. Methylnitrosoethylamine was more effective as a liver carcinogen by gavage than in drinking water and gave rise to tumors of the lung and nasal mucosa by the former route, but not the latter. By gavage, methylnitroso-2-oxopropylamine and methylnitroso-2-hydroxypropylamine induced mainly tumors of the esophagus, as they did when given to rats in drinking water, but the potency was greater by gavage. At a higher dose rate (85 micromoles per week) methylnitrosohydroxypropylamine induced a high incidence of mesenchymal tumors of the kidney and lung tumors, in addition to esophageal tumors, but methylnitrosooxopropylamine did not. The tobacco-specific carcinogen NNK induced tumors of the liver, and to a lesser extent, of the lung and nasal mucosa when given by gavage to rats, as it did by other routes of administration. The similarly basic nitrosamine methylnitroso-N, N-dimethylaminoethylamine was equally potent, whether administered by gavage or in drinking water to rats, and gave rise only to tumors of the esophagus. The cyclic nitrosamine nitrosomorpholine was equally effective by gavage and in drinking water, but induced in rats more esophageal tumors by gavage in addition to a high incidence of liver tumors. Its 2-hydroxy derivative, a postulated metabolic intermediate of nitrosodiethanolamine, was a very much weaker carcinogen than either the latter or nitrosomorpholine, and induced low incidences of liver and lung tumors toward the end of the lifespan of the rats.
Broadly Neutralizing Antibodies and the Development of Vaccines (2015)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Iron sensitizes keratinocytes and fibroblasts to UVA-mediated matrix metalloproteinase-1 through TNF-α and ERK activation (2010)

Oestrogen deficiency is regarded as the main causative factor in postmenopausal skin ageing and photoageing. While women after menopause experience low levels of oestrogen because of cease of ovarian function, they are also exposed to high levels of iron as a result of cessation of menstruation. In this study, we investigated whether this increase in iron presents a risk to the postmenopausal skin. Because of the lack of appropriate animal models to closely mimic the low oestrogen and high iron conditions, we tested the hypothesis in a high iron and low oestrogen culture model. Here, we showed that primary human dermal fibroblasts exposed to iron did not affect the baseline levels of matrix metalloproteinase-1 (MMP-1) activity. However, the iron-exposed fibroblasts were sensitized to UVA exposure, which resulted in a synergistic increase in MMP-1. UVA activated the three members of MAPK family: ERKs, p38, and JNKs. Additional activation of ERKs by iron contributed to the synergistic increases. Primary normal human epidermal keratinocytes (NHEK) did not respond to iron or UVA exposure as measured by MMP-1, but produced tumor necrosis factor-alpha (TNF-α) in the media, which then stimulated MMP-1 in fibroblasts. Our results indicate that iron and UVA increase MMP-1 activity in dermal fibroblasts not only directly through ERK activation but also by an indirect paracrine loop through TNF-α released by NHEK. We conclude that in addition to oestrogen deficiency, increased iron as a result of menopause could be a novel risk factor by sensitizing postmenopausal skin to solar irradiation.
Relationship between parent mood and resilience and child health outcomes in pediatric asthma. (2019)

Higher parent-reported QOL and mood were significantly associated with better parent report of child asthma SFDs. Although parent resilience was associated with parent mood, it did not moderate the relationship to child SFDs. Future research is warranted to better understand the unique contribution of resilience in families with children with asthma. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
Comparative analysis of EpCAM high-expressing and low-expressing circulating tumour cells with regard to their clonal relationship and clinical value (2023)

Our data indicate that EpCAM low-expressing CTCs could be used as a valuable tumour surrogate material-although they may be prognostically less relevant than EpCAM high-expressing CTCs-and have particular benefit if no CTCs are detected using EpCAM-dependent technologies.
Alternating copolymerizations of styrene and acrylic monomers initiated with carbanions in the presence of ZnCl2 (1978)

Abstract On electrochemical initiation of alternating copolymerizations of styrene–acrylonitrile (AN) and styrene–diethyl fumarate (DEF) in the presence of ZnCl 2 , radical anions of AN–ZnCl 2 and DEF–ZnCl 2 complexes produced at the cathode were assumed to initiate copolymerization. In analogy with the cathode‐initiated copolymerization, the radical anions of AN–ZnCl 2 and DEF–ZnCl 2 , generated with the carbanions such as sodium naphthalene, disodium α‐methylstyrene tetramer dianion, and butyllithium, were also found to produce alternating copolymers of styrene–AN and styrene–DEF. On the contrary, no polymers were obtained from methyl methacrylate (MMA)–styrene and methacrylonitrile (MAN)–styrene in the presence of ZnCl 2 either with carbanions or by electrochemical reduction. Styrene–MAN–ZnCl 2 yielded an alternating copolymer with carbanions upon introduction of oxygen.
Helicobacter pylori-induced STAT3 activation and signalling network in gastric cancer (2014)

H. pylori infection triggers the activation of STAT3 and de-regulates multitude of tumorigenic genes which may contribute to the initiation and progression of gastric cancer.
Privacy-Preserving Deep Learning Based on Multiparty Secure Computation: A Survey (2021)

Deep learning (DL) has demonstrated superior success in various of applications, such as image classification, speech recognition, and anomalous detection. The unprecedented performance gain of DL largely depends on tremendous training data, high-performance computation resources, and well-designed model structures. However, privacy concerns raise from such necessities. First, as the training data are usually distributed among multiple parties, directly exposing and collecting such large amount of data could violate the laws especially for private information, such as personal identities, medical records, and financial profiles. Second, locally deploying advantageous computation resources is costly for individual party having partial data. Third, direct release of well-trained model parameters threatens the information about training data or the intellectual property of model owners. Therefore, individual party prefers outsourcing computation (data) in a secure way to powerful cloud servers such as Microsoft Azure, and how to enable the cloud servers to perform DL algorithms without revealing data owners&#x2019; private information and model owners&#x2019; valuable parameters is emerging as an urgent task, which is termed as privacy-preserving (outsourcing) DL. In this article, we review the state-of-the-art researches in privacy-preserving DL based on multiparty secure computation with data encryption and summarize these techniques in both training phase and inference phase. Specifically, we categorize the techniques with respect to the linear and nonlinear computations, which are the two basic building blocks in DL. Following a comprehensive overview of each research scheme, we present primary technical hurdles needed to be addressed and discuss several promising directions for future research.
A very low complexity block turbo decoder composed of extended Hamming codes (2002)

This paper presents a very low complexity block turbo decoder composed of extended Hamming codes. New efficient complexity reduction algorithms are proposed including simplifying the extrinsic information computation and soft inputs updating algorithm. For performance evaluation, [eHamming (32,26,4)]/sup 2/ and [eHamming (64,57,4)]/sup 2/ block turbo code transmitted over an AWGN channel using BPSK modulation are considered. Extra 0.3 dB to 0.4 dB coding gain is obtained if compared with the scheme proposed in Pyndiah et al., (1996), and the hardware overhead is negligible. The complexity of our new block turbo decoder is about ten times less than that of the near-optimum block turbo decoder with a performance degradation of only 0.5 dB. Other schemes such as reduction of test patterns in the Chase algorithm and memory saving techniques are also presented.
Blind separation of signal and multipath interference for synthetic aperture sonar (2003)

Multipath interference is a major source of noise for synthetic aperture sonar systems operating in shallow water. Motivated by this problem, we present an iterative algorithm for blindly separating the signal from the multipath interference that uses differences in the temporal coherence properties of the signal and multipaths caused by sea surface roughness to estimate the optimum filter weights. The filter weights are estimated by minimizing the circular variance of the phase differences between overlapping vertical phase centers. An important advantage of this approach is that signal-free training data and accurate array calibration information are not needed. Experimentally we show that the blind separation performance is competitive with high resolution angle of arrival estimation and compares favorably to the Cramer-Rao lower bound predicted error.
Robotic Arm Comprising Two Bending Segments (2010)

The figure shows several aspects of an experimental robotic manipulator that includes a housing from which protrudes a tendril- or tentacle-like arm 1 cm thick and 1 m long. The arm consists of two collinear segments, each of which can be bent independently of the other, and the two segments can be bent simultaneously in different planes. The arm can be retracted to a minimum length or extended by any desired amount up to its full length. The arm can also be made to rotate about its own longitudinal axis. Some prior experimental robotic manipulators include single-segment bendable arms. Those arms are thicker and shorter than the present one. The present robotic manipulator serves as a prototype of future manipulators that, by virtue of the slenderness and multiple- bending capability of their arms, are expected to have sufficient dexterity for operation within spaces that would otherwise be inaccessible. Such manipulators could be especially well suited as means of minimally invasive inspection during construction and maintenance activities. Each of the two collinear bending arm segments is further subdivided into a series of collinear extension- and compression-type helical springs joined by threaded links. The extension springs occupy the majority of the length of the arm and engage passively in bending. The compression springs are used for actively controlled bending. Bending is effected by means of pairs of antagonistic tendons in the form of spectra gel spun polymer lines that are attached at specific threaded links and run the entire length of the arm inside the spring helix from the attachment links to motor-driven pulleys inside the housing. Two pairs of tendons, mounted in orthogonal planes that intersect along the longitudinal axis, are used to effect bending of each segment. The tendons for actuating the distal bending segment are in planes offset by an angle of 45 from those of the proximal bending segment: This configuration makes it possible to accommodate all eight tendons at the same diameter along the arm. The threaded links have central bores through which power and video wires can be strung (1) from a charge-coupled-device camera mounted on the tip of the arms (2) back along the interior of the arm into the housing and then (3) from within the housing to an external video monitor.
Coherent photoproduction of π[sup +] from [sup 3]He with CLAS at Jefferson Lab (2011)

We have measured the differential cross section for the γ3He→π+t reaction. This reaction was studied using the CEBAF Large Acceptance Spectrometer (CLAS) at Jefferson Lab. Real photons produced with the Hall‐B bremsstrahlung tagging system in the energy range from 0.5 to 1.55 GeV were incident on a cryogenic liquid 3He target. The differential cross sections for the γ3He→π+t reaction were measured as a function of photon‐beam energy and pion‐scattering angle. Theoretical predictions to date cannot explain the large cross sections except at backward angles, showing that additional components must be added to the model.
Estimation of surface normal vectors based on 3D scanning from heating approach (2012)

The Scanning From Heating is a 3D scanning approach initially developed to realise 3D acquisition of transparent or specular surfaces. A laser source is used to create a local heating point. An infrared camera is used to observe the IR radiation emitted by the scene. The 2D coordinates of the heated point are computed in the 2D image of the camera. Knowing the parameters of the system (which are obtained by a previous calibration), the 3D coordinates of the point are computed using triangulation method. In this article we will present an extension of this technique. We propose here to analyse the shape of the hot spot observed by the IR camera, and, from the analysis to determine information on the local orientation of the surface at each measured point.
Measurements of Intensity Dynamics at the Periphery of the Nucleus (2019)

The aim of this chapter is to learn how to construct a workflow for measuring the fluorescence intensity localized to the nuclear envelope. For this purpose, the nucleus image is segmented to create a mask along the nuclear rim. The reader will learn a typical technique for automatically delineating the segmented area by post-processing using the mathematical morphology algorithm, and how to loop that piece of ImageJ macro and iterate through multiple image frames to measure changes in fluorescence intensity over time. This chapter is also a good guide for learning how to convert ImageJ macro commands recorded by the Command Recorder to a stand-alone ImageJ macro.
Security Policy Management for Handheld Devices (2003)

The adoption of wireless technologies and handheld devices is becoming widespread in business, industry, and government organizations. The use of handheld devices introduces new risks to existing enterprise computing resources. Therefore, organizations require new strategies to mitigate the security risks associated with the integration of wireless technologies into existing computing environments. In this paper, we describe a framework for managing user privileges on handheld devices. Our framework aims at assisting enterprise security officers in creating, distributing, and enforcing group and individual security policies for Personal Digital Assistants, and helping users to automatically comply with their organization’s security policy. Details of a proof-of-concept implementation of the framework are also provided
The Levels of Trace Elements in Australian Export Steaming Coals (1990)

Data on the concentration levels of a comprehensive range of trace elements as well as natural radionuclides has been obtained on 87 representative samples of Australian export steaming coals. The results confirm the relatively low concentrations of most trace elements, particularly those of environmental concern, compared to overseas coals. The data is intended to enhance the environmental acceptability of Australian steaming coals in export markets.
Pensiones en Chile: ¿Qué Hubiese Ocurrido sin la Reforma de 1981? (2006)

Este documento discute qué hubiese ocurrido en la economía chilena si no se hubiera realizado la reforma de pensiones de 1981. El énfasis de la discusión se pone en la sustentabilidad fiscal del sistema de pensiones, su grado de cobertura, niveles de pensiones y su impacto en la acumulación de capital, empleo y PIB. Para realizar esta discusión, este documento realiza ejercicios de simulación de un modelo macroeconómico. Los resultados de nuestro ejercicio se pueden clasificar en tres categorías: (a) situación financiera del sistema de reparto, (b) situación del sistema de pensiones en términos de cobertura y pensiones y (c) efectos macroeconómicos. Nuestras simulaciones indican que el sistema mostraba altos y crecientes déficits desde el año 2000 en adelante. La discusión relativa a la cobertura de pensiones y el monto de las pensiones trae ciertos resultados a destacar. En primer lugar la cobertura de beneficios es cercana al 40% en el largo plazo, y una fracción muy significativa recibe pensiones mínimas. Más aún, nuestros resultados muestran que el monto de las pensiones promedio que se obtienen en el sistema son relativamente modestas. En relación a los impactos macroeconómicos, el trabajo encuentra impactos a partir de los cambios en decisiones de ahorro de los hogares.
Detection and Classification of SPLCV Isolates in the U.S. Sweetpotato Germplasm Collection via a Real-Time PCR Assay and Phylogenetic Analysis (2011)

The United States Department of Agriculture-Agricultural Research Service sweetpotato (Ipomoea batatas) germplasm collection contains accessions that were initially collected from various countries worldwide. These materials have been maintained and distributed as in vitro plantlets since the mid-1980s. The status of viral infection by the emerging Sweet potato leaf curl virus (SPLCV) and other Begomovirus spp. in this germplasm has yet to be determined. In order to minimize the potential distribution of virus-infected clones, all accessions in the collection were tested for SPLCV using a real-time polymerase chain reaction assay. In total, 47 of 701 accessions of in vitro plantlets tested positive for SPLCV. The presence of SPLCV detected in these materials was confirmed via biological indexing using the indicator plants I. nil and I. muricata. Symptoms appeared more rapidly on I. muricata than on I. nil. Nucleotide polymorphisms among the isolates were evaluated by sequencing the AV1 coat protein gene from 24 SPLCV-infected accessions. The results revealed that the SPLCV isolates shared high sequence identity. Ten nucleotide substitutions were identified, most of which were synonymous changes. Phylogenetic analysis was conducted on those 24 SPLCV isolates in combination with six described SPLCV species and various SPLCV strains from GenBank to evaluate the relationships among viral species or strains. The results from this analysis indicated that most of the AV1 genes derived from previously classified SPLCV species clustered together, some of which formed well-supported monophyletic clades, further supporting the current taxonomy. Overall, identification of SPLCV-infected germplasm will allow approaches to be employed to eliminate the virus from the collection and limit the distribution of infected materials.
Holistic multi-resource allocation for multicore real-time virtualization (2019)

This paper presents vC2M, a holistic multi-resource allocation framework for real-time multicore virtualization. vC2M integrates shared cache allocation with memory bandwidth regulation to mitigate interferences among concurrent tasks, thus providing better timing isolation among tasks and VMs. It reduces the abstraction overhead through task and VCPU release synchronization and through VCPU execution regulation, and it further introduces novel resource allocation algorithms that consider CPU, cache, and memory bandwidth altogether to optimize resources. Evaluations on our prototype show that vC2M can be implemented with minimal overhead, and that it substantially improves schedulability over existing solutions.
A Sall4 mutant mouse model useful for studying the role of Sall4 in early embryonic development and organogenesis (2007)

SALL4 is a homologue of the Drosophila homeotic gene spalt, a zinc finger transcription factor, required for inner cell mass proliferation in early embryonic development. It also interacts with other transcription factors to control the development of the anorectal region, kidney, heart, limbs, and brain. Truncating mutations in SALL4 cause Okihiro syndrome, manifest as Duane anomaly, radial ray defects and sensorineural and conductive deafness. We report the characterization of a novel murine Sall4 null allele created by bacterial recombineering in ES cells. Homozygous mutant mice exhibit early embryonic lethality. Heterozygous mutant mice recapitulate phenotypic features of Okihiro syndrome including deafness, lower anogenital tract abnormalities, renal hypoplasia, anencephaly, Hirschprung's disease, and skeletal defects. This phenotype shows important differences in cardiac and ear manifestations to previously characterized Sall4 mutant alleles and should prove useful for the investigation of the influence of modifier alleles and protein interactions on the transcriptional regulatory function of Sall4.
Direct processing of clinically relevant large volume samples for the detection of sexually transmitted infectious agents from urine on a microfluidic device (2012)

Urine is a preferred specimen for nucleic acid-based detection of sexually transmitted infections (STIs) but represents a challenge for microfluidic devices due to low analyte concentrations. We present an extraction methodology enabling rapid on-chip nucleic acid purification directly from clinically relevant sample volumes up to 1 ml and subsequent PCR amplification detection.