Antibiotic Management in Patients with Chronic Bronchitis and Emphysema (1972)

Editorials1 December 1972Antibiotic Management in Patients with Chronic Bronchitis and EmphysemaBENJAMIN BURROWS, M.D., WILLIAM NEVIN, M.D.BENJAMIN BURROWS, M.D.Search for more papers by this author, WILLIAM NEVIN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-77-6-993 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptBronchopulmonary infection has been suspected of playing various roles in the development and course of chronic bronchitis and emphysema. As discussed below, there are theoretical reasons to suspect that infection might be an important causative factor. Clinical observations suggest that it does at least accelerate the course of these diseases. And without doubt, purulent exacerbations of bronchitis are major causes of excess morbidity and mortality in patients with these obstructive lung disorders.Recognition of the association between severe hereditary alpha1-antitrypsin deficiency and pulmonary emphysema (1) has rekindled interest in the possible role of bronchopulmonary infection in the development of this...References1. FALKBRISCOE GW: Alpha1-antitrypsin deficiency in chronic obstructive pulmonary disease (editorial). Ann Intern Med 72:427-429, 1970 LinkGoogle Scholar2. HOGGMACKLEMTHURLBECK JPW: Site and nature of airway obstruction in chronic obstructive lung disease. N Engl J Med 278:1355-1360, 1968 CrossrefMedlineGoogle Scholar3. GREEN G: The J. Burns Amberson Lecture—In defense of the lung. Am Rev Resp Dis 102:691-703, 1970 MedlineGoogle Scholar4. STOREYMORGANDRAY PWA: Chronic obstructive airway disease bacterial and cellular content of sputum. Am Rev Resp Dis 90:730-735, 1964 MedlineGoogle Scholar5. Editorial: Chemotherapy of bronchitis. Br Med J 1:125, 1970 CrossrefMedlineGoogle Scholar6. PINESRAAFATPLUCIRESKI AHK: Antibiotic regimens in severe and acute purulent exacerbations of chronic bronchitis. Br Med J 2:735-738, 1968 CrossrefMedlineGoogle Scholar7. PETERSENESMANNHONCKE EVP: A controlled study of the effect of treatment on chronic bronchitis, an evaluation using pulmonary function tests. Acta Med Scand 182:293-305, 1967 CrossrefMedlineGoogle Scholar8. PINESRAAFATGREENFIELD AHJ: Antibiotic regimens in moderately ill patients with purulent exacerbations of chronic bronchitis. Br J Dis Chest 66:107-115, 1972 CrossrefMedlineGoogle Scholar9. FLETCHERBALLCARSTAIRS CJL: Value of chemoprophylaxis and chemotherapy in early chronic bronchitis. A report to the Medical Research Council by their working party on trials of chemotherapy in early chronic bronchitis. Br Med J 1:1317-1322, 1966 CrossrefMedlineGoogle Scholar10. PINESGREENFIELDRAAFAT AJH: Chloramphenicol and ampicillin compared in elderly patients with severe purulent exacerbations of bronchitis. Br J Dis Chest 66:116-120, 1972 CrossrefMedlineGoogle Scholar11. PINESRAAFATGREENFIELD AHJ: Penicillin, ampicillin, and cephaloridine in severe exacerbations of purulent bronchitis in elderly patients. Br J Dis Chest 65:91-97, 1971 CrossrefMedlineGoogle Scholar12. JOHNSTONMCNEILLSMITH RRD: Five-year winter chemoprophylaxis for chronic bronchitis. Br Med J 4:265-269, 1969 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: University of Arizona College of Medicine Tucson, Ariz. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByCommunity-acquired bronchitis and pneumoniaDiagnosis and Treatment of Cystic FibrosisTherapy of Chronic Obstructive Airways DiseaseMedical Management of EmphysemaFamilial bronchiectasisAntimicrobial Drugs and Infections in Ambulatory Patients: Some Problems and PerspectivesAirway Changes in Young Smokers That May Antedate Chronic Obstructive Lung DiseaseKlinisches Bild der nichtatopischen AtemwegsobstruktionWhen to Hospitalize the COPD PatientOxygen and nonventilatory therapy of respiratory failure in copdAmbulatory care and rehabilitation in copdInfectious diseases: annual review of significant publications. 1 December 1972Volume 77, Issue 6Page: 993-995KeywordsAntibioticsBronchitisChronic bronchitisEmphysemaLungsMorbidityMortalityPulmonary diseases Issue Published: 1 December 1972 PDF DownloadLoading ...