gebhart/patrepeval huggingface dataset:
The Anti-inflammatory Actions of Tilorone Hydrochloride (1975)

Tilorone suppressed inflammation induced by immune (direct passive Arthus reaction) as well as by non-immune agents (carrageenam-induced paw edema and abscess formation), if the compound is given 24 hr prior to the proinflammatory agonists. The non-immune anti-inflammatory effect is independent of the adrenals. A surprising findings was that total serum hemolytic complement is markedly elevated 24 hr after a single dose of tilorone.
Microstructural Evolution and Mechanical Properties of High Purity Aluminium Processed by Equal-Channel Angular Pressing (2007)

High purity (99.999%) aluminium was subjected to Equal-Channel Angular Pressing (ECAP) at room temperature for up to 8 passes through route BC using a die having a channel angle of 90°. Hardness measurements and tensile tests were conducted at room temperature with respect to the number of ECAP passes. It is shown that the hardness and the tensile strength increased to take a maximum at 2 passes. However, unusual behaviour was observed such that further straining by ECAP for more than 2 passes decreased the hardness and tensile strength. Furthermore, the total elongation and the uniform elongation were enhanced with straining by ECAP. Microstructural observation using transmission electron microscopy revealed that straining by ECAP for 2 passes led to the development of a subgrain structure having dislocations within some subgrains and tangled dislocations near subgrain boundaries. After 8 passes, the grains became lager with the grain size of ∼15 μm and with the grain boundaries sharpened and clearly defined. Within such grains, subgrain boundaries were formed with an average separation of ∼3 μm and with the dislocation density very low. It is considered that the high dislocation mobility arising from high stacking fault energy and very low level of impurities were responsible for the unusual tensile behaviour and the difficulty in reducing the grain size to the submicrometer level. It is also considered that the grain refinement occurred due to evolution of subgrain boundaries to high angle boundaries, initially mutual coalescence of dislocations to subgrain boundaries followed by increasing misorientation angles by merging nearby dislocations.
Vitamin D receptor gene polymorphisms and disease free survival after radical prostatectomy (2004)

Overall vitamin D receptor polymorphisms did not predict pathologic features of prostate cancer but may impact on risk of recurrence among men in certain risk groups. Analysis of polymorphisms may provide clues about the mechanisms through which vitamin D exerts its inhibitory effects on prostate cancer in vivo in men.
Unusual stabilization of formylmetal complexes (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTUnusual stabilization of formylmetal complexesB. A. Narayanan, C. A. Amatore, and J. K. KochiCite this: Organometallics 1984, 3, 5, 802–804Publication Date (Print):May 1, 1984Publication History Published online1 May 2002Published inissue 1 May 1984https://pubs.acs.org/doi/10.1021/om00083a027https://doi.org/10.1021/om00083a027research-articleACS PublicationsRequest reuse permissionsArticle Views87Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Magnetic polarisability of thick multiple rectangularapertures (1999)

The magnetostatic potential distribution through multiple rectangular apertures in a thick conducting plane is analysed. Series solutions are given for the transverse and longitudinal magnetic polarisability of multiple rectangular apertures with various depth and shapes. The differences between electric and magnetic cases are discussed.
Low Data-Rate Video Conferencing (1986)

A feasibility study has been completed on a narrow-band video conferencing system. Gray-scale images are converted to bi-level images and further processed to remove inconsistencies within the mappings. Ordered run-length coding of difference frames is used to update the areas of the image that are most likely to change and to be perceptually important first. Sequences of 15 (128 x 120) bi-level frames/s have been successfully transmitted at rates hard-limited at 19.2 kbits/s.
“Pushing the margin:” utilization of renal autotransplantation to achieve complete resection in vena caval leiomyosarcomas (2019)

We report the case of a 19-year-old female who underwent resection of the sub- and infrahepatic inferior vena cava (IVC) with concomitant left kidney autotransplantation for leiomyosarcoma. Based on the available literature, this is the youngest patient reported undergoing IVC resection and reconstruction with concomitant renal autotransplant. We review the literature, presentation, and a unique treatment option for this infrequent pathology.
Intradialytic parenteral nutrition improves protein and energy homeostasis in chronic hemodialysis patients (2002)

Decreased dietary protein intake and hemodialysis-associated protein catabolism are among several factors that predispose chronic hemodialysis (CHD) patients to protein calorie malnutrition. Since attempts to increase protein intake by dietary counseling are usually ineffective, intradialytic parenteral nutrition (IDPN) has been proposed as a potential therapeutic approach in malnourished CHD patients. In this study, we examined protein and energy homeostasis during hemodialysis in seven CHD patients at two separate hemodialysis sessions, with and without IDPN administration. Patients were studied 2 hours before, during, and 2 hours following a hemodialysis session, using a primed constant infusion of L-(1-(13)C) leucine and L-(ring-(2)H(5)) phenylalanine. Our results showed that IPDN promoted a large increase in whole-body protein synthesis and a significant decrease in whole-body proteolysis, along with a significant increase in forearm muscle protein synthesis. The net result was a change from an essentially catabolic state to a highly positive protein balance, both in whole-body and forearm muscle compartments. We conclude that the provision of calories and amino acids during hemodialysis with IDPN acutely reverses the net negative whole-body and forearm muscle protein balances, demonstrating a need for long-term clinical trials evaluating IDPN in malnourished CHD patients.
Magnesium Intake and Self‐Reported Health in Pregnant Women (2010)

Low magnesium (Mg) intake may contribute to diseases of pregnancy such as pre‐eclampsia and gestational diabetes. Reports on plasma Mg levels and diseases risk have been mixed: plasma Mg is known to be a poor indicator of overall Mg status. Erythrocyte Mg, both intra‐cellular and intra‐membrane, has been shown to be lower in diseased compared to healthy pregnancies. Studies linking Mg intake to risk of diseases of pregnancy have been inconclusive. We studied if Mg intakes correlate with self‐reported health in women in the US using the NHANES 1999–2004 dataset (6633 women, 15–54 yrs old). We estimated how many women consume &lt;EAR, the measure of inadequacy, of Mg. ~50% of pregnant and &gt;60% of all women aged 15–54 consume &lt;EAR of Mg. Factors (micronutrient intakes, demographic, social, economic) that could influence self‐reported health were evaluated by logistic regression. Mg intake &lt;EAR showed the strongest significant decrease in odds of self‐reporting great health in pregnant women (OR=0.35), but not in child‐bearing age women at large. These observations may have important implications, as most over‐the‐counter and prescription prenatal vitamins do not currently include Mg.
A new synthesis of lactones from tertiary alkenylcarbinols by cobaltcatalyzed photocarbonylation under ambient conditions (1995)

In the presence of a Co catalyst, tertiary vinyl-, propenyl-, and allylcarbinols were chelatively cycloadded to carbon monoxide to produce lactones by xanthone-sensitized photoreaction in tetrahydrofuran, under CO at 1 atmosphere and at room temperature. At lower temperatures the isomerization of alkenylcarbinols was suppressed and lactones were obtained with improved selectivity. The photoprocess was facilitated by addition of pyridine or hydrogen and retarded in presence of amines or phosphines. Mechanistic interpretations for the process and the accompanying effects are discussed. Keywords: chelative carbonylation, photocarbonylation, carbonylation of olefins, lactones synthesis from alkenylalcohols.
Interaction of Neuropeptides and Cultured Glial (Müller) Cells of the Chick Retina: Elevation of Intracellular Cyclic AMP by Vasoactive Intestinal Peptide and Glucagon (1984)

Vasoactive intestinal peptide (VIP) and, to a lesser extent, glucagon were found to increase intracellular cyclic AMP rapidly in cultured glial (Müller) cells of the chick embryo retina. Although VIP elicited higher cyclic AMP accumulation than glucagon at each concentration tested, the half-maximal concentrations were similar, i.e., 6 X 10(-8) M for VIP and 8 X 10(-8) M for glucagon. Secretin had a minimal effect on cyclic AMP accumulation even at a very high (5 X 10(-6) M) concentration. Several other peptide and nonpeptide putative agonists also had little effect on cyclic AMP accumulation. The cultured Müller cell may thus be a useful model for examining VIP and glucagon effects on glial elements of the CNS.
A POSIÇÃO DA IGREJA CATÓLICA DIANTE DO USO DE CÉLULAS- TRONCO EMBRIONÁRIAS PARA PESQUISA (2013)

O presente trabalho tem por objetivo analisar sob um olhar teologico a ciencia e bioetica, buscando conceitos e saberes sobre a dignidade da vida, e apontar para os limites da ciencia e a importância da religiao para tomada de decisoes a respeito da bioetica. A espiritualidade deve ser considerada uma area relevante, pois tem uma grande repercussao e reflexao sobre a vida humana. Na busca por uma relacao mais positiva da ciencia e religiao, com base nos direitos humanos e opiniao publica, o presente trabalho pretende esclarecer reacoes e implicacoes em torno do uso de celulas-tronco embrionarias a partir de colocacoes e questionamentos da Igreja Catolica. A discussao se situa na utilizacao de embrioes congelados que na maioria sao armazenados em clinicas de Reproducao Assistida. Busca apresentar possibilidades e avancos que o uso das celulas-tronco embrionarias traz para a cura de muitas doencas que ha pouco tempo se diziam sem cura. Na verdade, nenhuma cura ainda foi elaborada com sucesso a partir de celulas embrionarias, sendo apenas uma promessa. Ja com celulas adultas ha curas comprovadas, praticadas, por exemplo, no Hospital Sao Lucas da PUC-RS, que nao usa, por principio, celulas-tronco embrionarias. Aponta para uma perspectiva de reflexao teologica em dialogo com as ciencias, culturas e religioes, caracterizando os desafios e possibilidades para a vida social, politica, economica e cultural da sociedade, interagindo com a Igreja Catolica e suas crencas. A grande questao esta na aceitacao do uso dessas celulas, pois, para essas pesquisas, o embriao deve ser destruido. Isto implica em questoes eticas e religiosas, pois algumas posicoes, entre elas a da Igreja Catolica, consideram o embriao uma pessoa. Segundo os cientistas, seriam usados apenas embrioes descartados pelas clinicas de fertilizacao e que, mesmo se implantados no utero de uma mulher, dificilmente resultariam em uma gravidez, ou seja, embrioes que provavelmente nunca se desenvolverao. Porem, essa ideia esbarra na oposicao de setores religiosos e grupos anti-aborto que consideram que a vida comeca no momento da concepcao, ou seja, defendem que a utilizacao de embrioes resultantes de ovulos fecundados in vitro em clinicas de fertilizacao humana para pesquisas equivaleria ao aborto. A metodologia de pesquisa utilizada e bibliografica, caracterizando pontos principais na historia no desenvolvimento das pesquisas com celulas-tronco, construindo um dialogo entre teologia e bioetica em busca de sentido e preocupados com o futuro. PALAVRAS-CHAVE: Celulas - tronco embrionarias, Igreja Catolica, Pesquisa com embrioes.
High-Temperature Load Transfer in Nicalon/Bmas Glass-Ceramic Matrix Composites (2008)

High-temperature load transfer characteristics of Nicalon fiber-reinforced BMAS glass-ceramic composites were studied. Specimens were crept at 1100 °C under constant tensile load to accomplish load transfer from the matrix to the fibers, and then cooled under load. Upon removal of the load at room-temperature, the matrix was put into compression by the elastic recovery of the fibers. This compressive residual stress in the matrix increased the proportional limit of the composite as determined by room-temperature tensile stress-strain behavior. Changes in the state of residual stress in the matrix were also confirmed with X-ray Diffraction measurements (XRD).
A Novel Pretreatment-Free Duplex Chamber Digital PCR Detection System for the Absolute Quantitation of GMO Samples (2016)

Digital polymerase chain reaction (PCR) has developed rapidly since it was first reported in the 1990s. However, pretreatments are often required during preparation for digital PCR, which can increase operation error. The single-plex amplification of both the target and reference genes may cause uncertainties due to the different reaction volumes and the matrix effect. In the current study, a quantitative detection system based on the pretreatment-free duplex chamber digital PCR was developed. The dynamic range, limit of quantitation (LOQ), sensitivity and specificity were evaluated taking the GA21 event as the experimental object. Moreover, to determine the factors that may influence the stability of the duplex system, we evaluated whether the pretreatments, the primary and secondary structures of the probes and the SNP effect influence the detection. The results showed that the LOQ was 0.5% and the sensitivity was 0.1%. We also found that genome digestion and single nucleotide polymorphism (SNP) sites affect the detection results, whereas the unspecific hybridization within different probes had little side effect. This indicated that the detection system was suited for both chamber-based and droplet-based digital PCR. In conclusion, we have provided a simple and flexible way of achieving absolute quantitation for genetically modified organism (GMO) genome samples using commercial digital PCR detection systems.
An Aerial Survey of Water Turbidity and Laser Depth Sounding Performance Along the Queensland Coast (1981)

The performance of the WRELADS laser airborne depth sounder has been assessed in North Queensland coastal waters from Townsville to Torres Strait. This was achieved by recording water turbidity and maximum sounding depth in the aircraft along the flight path. The parameter used in the aerial survey as a measure of water turbidity was related to beam attenuation coefficient measured from a boat in a joint aircraft and boat trial. Data relating the statistical distribution of turbidity to water depth were obtained and compared with the observed performance characteristic in order to indicate the proportion of Queensland coastal waters suitable for sounding with an airborne laser sounder. (Author)
Upgrade Levels of the Bosch ABS (1986)

&lt;div class="htmlview paragraph"&gt;The Bosch ABS for passenger cars which has been in production since 1978 has been described in numerous publications. Following the gathering of extensive experience with the Bosch ABS and its installation in the different models of passenger car, the concept has been revised with various upgrade levels in order to further optimize braking performance on µ-split road surfaces with different right/left adhesion coefficients, in order further to improve the operation of the system when braking on very slippery road surfaces and also to adapt the control algorithm to four-wheel-drive vehicles with differential locks.&lt;/div&gt;
Triglyceride characteristics of cocoa butter from cacao fruit matured in a microclimate of elevated temperature (1980)

Abstract Generally, the melting characteristic of cocoa butter is relatively constant. However, softer than normal butter is sometimes encountered. In Brazil the occurrence of soft butter has been correlated with mean daily temperature during the cropping season. The temperature effect was, therefore, studied more fully by positioning heat lamps near fruit of cacao to create a microclimate of elevated temperature during the most active period of lipid biosynthesis. As determined by differential scanning calorimetry, cocoa butter from these fruits, contained more solid fat at 16 C, and 20 C and 24 C than butter from control fruit matured in a normally lower temperature climate. The temperature effect on softness was in accordance with differences found in triglyceride types. S 2 U and SU 2 triglycerides from heat‐exposed samples were 88.5% and 8.9%, respectively, compared to 79.3% and 18.3% for cocoa butter from control fruit. Additional evidence of differences due to growth temperature was obtained by analysis of triglyceride fractions separated by high‐performance liquid chromatography.
Reaction of two-coordinate phosphorus compounds with Group IIIA alkyls: a novel double group shift and concomitant cyclization (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReaction of two-coordinate phosphorus compounds with Group IIIA alkyls: a novel double group shift and concomitant cyclizationA. H. Cowley, J. E. Kilduff, and J. C. WilburnCite this: J. Am. Chem. Soc. 1981, 103, 6, 1575–1577Publication Date (Print):March 1, 1981Publication History Published online1 May 2002Published inissue 1 March 1981https://pubs.acs.org/doi/10.1021/ja00396a055https://doi.org/10.1021/ja00396a055research-articleACS PublicationsRequest reuse permissionsArticle Views49Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ASSESSMENT OF TECHNOLOGY FOR DETECTION OF STRESS CORROSION CRACKING IN GAS PIPELINES. FINAL REPORT, JULY 1993-MARCH 1994 (1994)

The objective of the project was to assess the nondestructive evaluation (NDE) technology that may be applied to natural gas steel pipelines for the detection of stress corrosion cracking (SCC). In particular, the application of such technology would be from the inside of the pipe while the pipeline is in service, and inspection commonly called in-line inspection (ILI). The assessment focused on the basic NDE methods, ultrasonics and electromagnetics (including magnetic flux leakage). A third technology was data acquisition/analysis systems. Based on the experience of British Gas (BG) and others doing SCC inspections in different industries, crack discrimination is the important challenge for any such inspection system.
Temporal transcriptional logic of dynamic regulatory networks underlying nitrogen signaling and use in plants (2018)

This study exploits time, the relatively unexplored fourth dimension of gene regulatory networks (GRNs), to learn the temporal transcriptional logic underlying dynamic nitrogen (N) signaling in plants. Our "just-in-time" analysis of time-series transcriptome data uncovered a temporal cascade of <i>cis</i> elements underlying dynamic N signaling. To infer transcription factor (TF)-target edges in a GRN, we applied a time-based machine learning method to 2,174 dynamic N-responsive genes. We experimentally determined a network precision cutoff, using TF-regulated genome-wide targets of three TF hubs (CRF4, SNZ, and CDF1), used to "prune" the network to 155 TFs and 608 targets. This network precision was reconfirmed using genome-wide TF-target regulation data for four additional TFs (TGA1, HHO5/6, and PHL1) not used in network pruning. These higher-confidence edges in the GRN were further filtered by independent TF-target binding data, used to calculate a TF "N-specificity" index. This refined GRN identifies the temporal relationship of known/validated regulators of N signaling (NLP7/8, TGA1/4, NAC4, HRS1, and LBD37/38/39) and 146 additional regulators. Six TFs-CRF4, SNZ, CDF1, HHO5/6, and PHL1-validated herein regulate a significant number of genes in the dynamic N response, targeting 54% of N-uptake/assimilation pathway genes. Phenotypically, inducible overexpression of CRF4 <i>in planta</i> regulates genes resulting in altered biomass, root development, and <sup>15</sup>NO<sub>3</sub><sup>-</sup> uptake, specifically under low-N conditions. This dynamic N-signaling GRN now provides the temporal "transcriptional logic" for 155 candidate TFs to improve nitrogen use efficiency with potential agricultural applications. Broadly, these time-based approaches can uncover the temporal transcriptional logic for any biological response system in biology, agriculture, or medicine.
Inclusion by a diol host compound: structure and dynamics of volatile guest exchange (2001)

1,1,6,6-Tetraphenylhexa-2,4-diyne-1,6-diol (H) forms inclusion compounds with furan (1 and 2), tetrahydrofuran (3) and thiophene (4). 1, H·½FUR (H ∶ G = 1 ∶ ½), is a true clathrate, with the furan guest located in a cage formed by the host. The remaining structures (H ∶ G = 1 ∶ 2) 2, H·2FUR, 3, H·2THF and 4, H·2THIO are isostructural with guests located in channels. Selectivity and guest exchange reactions have been analysed and correlated to the topologies of the inclusion compounds.