gebhart/patrepeval huggingface dataset:
Fluorescence quenching studies of the aggregation behavior of the mixed micelles of bile salts and cetyltrimethylammonium halides (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFluorescence quenching studies of the aggregation behavior of the mixed micelles of bile salts and cetyltrimethylammonium halidesMartin Swanson Vethamuthu, Mats Almgren, Emad Mukhtar, and Pratap BahadurCite this: Langmuir 1992, 8, 10, 2396–2404Publication Date (Print):October 1, 1992Publication History Published online1 May 2002Published inissue 1 October 1992https://pubs.acs.org/doi/10.1021/la00046a010https://doi.org/10.1021/la00046a010research-articleACS PublicationsRequest reuse permissionsArticle Views416Altmetric-Citations56LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Natural Language Processing with Pandas DataFrames (2021)

Most areas of Python data science have standardized on using Pandas DataFrames for representing and manipulating structured data in memory. Natural Language Processing (NLP), not so much.
TLM modelling of microstrip patch antenna on ferrite substrate (2001)

A new TLM modelling method has been developed for patch antennas on magnetized ferrite substrate. The antenna has magnetically controllable resonance frequency and beam direction. The anisotropic permeability tensor of ferrite is modelled by state equations derived from the Polder tensor. Simulation results agree with measurement. © 2001 John Wiley & Sons, Inc. Int J RF and Microwave CAE 11: 131–139, 2001.
p53 autoantibodies from patients with colorectal cancer recognize common epitopes in the N- or C-terminus of p53. (2004)

Patients with various solid tumors develop antibodies against the growth suppressor protein p53. The percentage of positive sera for patients with colon cancer varied over a wide range, which might be due to the different methods or the different antigens, which were used for the detection of p53 autoantibodies. We analyzed sera from patients with diagnosed colon cancer by ELISA using native p53 from a tumor cell line as well as by Western blotting with full-length or C- or N-terminal fragments of p53. Finally, sera were analyzed with a peptide library consisting of 16-amino-acid peptides, which cover the entire p53 sequence. By using these different methods we found 7 out of 127 sera (5.5%) to be positive for p53 autoantibodies. Two antibodies out of 7 reacted only with epitopes in the N-terminus whereas 5 sera reacted with N- and C-terminal sequences. All of these sera recognized common epitopes, which are also detected by a number of mouse monoclonal antibodies indicating immune-dominant epitopes for mouse and man on the polypeptide chain of p53. The sequences of these epitopes might be useful for the treatment of tumor patients either by neutralizing p53 autoantibodies or for vaccination.
Amplified Detection of DNA through an Autocatalytic and Catabolic DNAzyme‐Mediated Process (2010)

Sense and sensibility: Amplified DNA detection is accomplished by the autocatalytic cleavage of a programmed nucleic acid structure based on the Mg2+-dependent DNAzyme E6 (see picture). The analyte sequence is autocatalytically generated by the DNAzyme from a reporter nucleic acid, which is labeled with a fluorophore and quencher at its two ends. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Increase of Lactoferrin Concentration in Mastitic Goat Milk (2004)

Lactoferrin concentration (LFC) in normal and mastitic milk of dairy goats were examined. LFC in bulk milk collected from 70 dairy goat farms and individual milk samples from 10 goats with mastitis were measured by enzyme-linked immunosorbent assay (ELISA) and their reaction time in methylene blue reduction test (MBRT) monitored. Bulk milk samples were categorized into three grades, such as high, normal and low, based on the reaction time in MBRT. The mean LFC in milk that was considered high quality (167 microg/ml) was significantly lower than that of those graded as normal (218 microg/ml) and low quality (304 microg/ml), while mean LFC in mastitic milk was 587 microg/m l. The correlation coefficient between milk LFC and MBRT time was found to be -0.7. Three goats were inoculated with Staphylococcus aureus into one of their udder halves. The mean milk LFC was found to be significantly higher (1500 microg/ml) than the control (30 microg/ml). These findings suggest that milk LFC may be useful as an index for intramammary infection in goats.
CHANGE IN PARTICLE SIZE DISTRIBUTIONS OF POLYDISPERSE AEROSOLS UNDERGOING BROWNIAN COAGULATION (1975)

The time-dependent change in particle size distributions of highly concentrated polydisperse aerosols undergoing Brownian coagulation was studied by numerically solving the basic equation of coagulation for various size distributions initially having log-normal form. The results were plotted in the forms of the change with time in cumulative size distributions and the changes in nominal geometric mean radius, as well as standard deviation for various initial distributions of aerosols. These figures showed that size distributions approached certain asymptotic ones, which might correspond to SPDF (self-preserving distribution function), almost independently of initial distributions as coagulation proceeded. The process of the approach to asymptotic distributions was also made clear by the graphs. Some of these results were verified by experimental results obtained by the ultramicroscopic size analysis previously developed by the authors.
The paired-like homeo box gene MHox is required for early events of skeletogenesis in multiple lineages. (1995)

Formation of cartilage and bone involves sequential processes in which undifferentiated mesenchyme aggregates into primordial condensations that subsequently grow and differentiate, eventually forming the adult skeleton. Although much has been learned about the structural molecules that compose cartilage and bone, little is known about the nuclear factors that regulate chondrogenesis and osteogenesis. MHox is a homeo box-containing gene that is expressed in the mesenchyme of facial, limb, and vertebral skeletal precursors during mouse embryogenesis. MHox expression has been shown to require epithelial-derived signals, suggesting that MHox may regulate the epithelial-mesenchymal interactions required for skeletal organogenesis. To determine the functions of MHox, we generated a loss-of-function mutation in the MHox gene. Mice homozygous for a mutant MHox allele die soon after birth and exhibit defects of skeletogenesis, involving the loss or malformation of craniofacial, limb, and vertebral skeletal structures. The affected skeletal elements are derived from the cranial neural crest, as well as somitic and lateral mesoderm. Analysis of the mutant phenotype during ontogeny demonstrated a defect in the formation and growth of chondrogenic and osteogenic precursors. These findings provide evidence that MHox regulates the formation of preskeletal condensations from undifferentiated mesenchyme.
Development of Image Psychophysics Software and Calibrator for Macintosh Systems (1996)

The core function of noninvasive psychophysical testing is the measurement of contrast sensitivity for spatial patterns specified with some mathematical luminance profile and a controlled time course. Desk-top computers would appear to be ideally suited for such a task and yet most of the software for such computers requires special-purpose hardware modifications and software that requires programming to achieve the desired experimental configuration. In particular, there seems to be no convenient software that take advantage of the graphics sophistication of the Macintosh computer.
CD34 Is Required for Dendritic Cell Trafficking and Pathology in Murine Hypersensitivity Pneumonitis (2011)

We conclude that CD34 is expressed by mucosal DCs and plays an important role in their trafficking through the lung and to the lymph nodes. Our data also suggest that CD34 may play a selective role in the efficient migration of these cells to a subset of chemokines.
Biokatalyse mit nicht‐natürlichen Aminosäuren: Enzymologie trifft Xenobiologie (2017)

Abstract Das Ziel der Xenobiologie ist das Design von biologischen Systemen, die mit nicht‐natürlichen biochemischen Funktionen ausgestattet sind, während die Enzymologie sich mit dem Verständnis von Enzymen auseinandersetzt, den Routinewerkzeugen der Biokatalyse. In der Biokatalyse werden Enzyme und Organismen dazu verwendet, um nützliche und leistungsfähige Biotransformationen in der synthetischen Chemie und Biotechnologie durchzuführen. In den vergangenen Jahren sind die Auswirkungen des Einbaus von nicht‐kanonischen Aminosäuren (nkAAs) in Enzyme, welche potentiell interessante Anwendung für die Biokatalyse aufweisen, mit gesteigerter Aufmerksamkeit untersucht worden. Mit diesem Aufsatz wollen wir einen Überblick über die Effekte und Auswirkungen neuer chemischer Funktionalitäten geben, mit denen Proteine ausgestattet wurden, um eine Vielzahl von Aspekten der enzymatischen Biokatalyse zu verbessern. Ein weiteres Hauptaugenmerk liegt auf zukünftigen Forschungsperspektiven, welche die nicht‐natürliche Mutagenese durch die Möglichkeiten des herkömmlichen Protein‐Engineerings ergänzen werden, um neue und vielseitige Biokatalysatoren mit Anwendungen in der synthetischen organischen Chemie und Biotechnologie zu generieren.
Recent Applications of Conjugated Polyelectrolytes in Optoelectronic Devices (2008)

Abstract Conjugated polyelectrolytes comprise an electronically delocalized backbone with pendant groups bearing ionic functionalities. Important new developments regarding their use to improve charge injection from metallic electrodes into organic semiconductors, a key requirement in emissive devices, have recently appeared. This article provides an overview of recent studies concerning the basic properties of conjugated polyelectrolytes as a function of molecular structure, and of optoelectronic devices with conjugated polyelectrolytes as essential functional components. Processes where more insightful mechanistic understanding is needed and areas of opportunity are discussed.
Rotor Blade Motion in a Vertical Sharp‐edged Gust (1954)

Part I—Constant Chord Blades 1. Summary Rotor/fuselage clearance is the most fundamental design consideration when laying out a new project, and it is essential to estimate this accurately at a very early stage. When centrifugal force droop stops are fitted to a rotor, the design criterion is usually the effect of a sharp‐edged down gust impinging on the rotor when it is not generating thrust; for example, whilst running‐up on the deck of an aircraft carrier. In this paper the dynamics of blade flapping motion are developed and a method for rapidly obtaining maximum gust deflexion is presented in the form of a Data Sheet (FIG. 5). This enables the maximum deflexion in a gust to be determined with no calculation. The solution obtained is exact; hitherto the only attempts to calculate gust deflexion known to the writer have developed an approximate equation of motion for the blade, and offered the Particular Integral as a sufficiently accurate solution. It is shown in Part II of this paper that this can be very misleading, and undcr‐estimates the true deflexion. In preliminary project design, the blade inertia is, of course, unknown. It is shown that this is a function of the coning angle and CL , basic only, probably the two most fundamental design parameters.
Molecular analysis of multifocal prostate cancer by comparative genomic hybridization (2008)

These results suggest that tumor foci within the same prostate represent independent tumors with differing clonal origin and that loss of 8p12-22 represents an important determinant of prostate cancer progression.
Energy- and Labor-aware Production Scheduling for Sustainable Manufacturing: A Case Study on Plastic Bottle Manufacturing (2017)

Among the potential roadmaps towards sustainable production, the emerging energy-cost-aware production scheduling philosophy is considered as one promising direction. Therein, sustainability objectives, e.g., minimization of energy consumption/cost of production processes and stabilization of the electricity grid, can be achieved by manufacturing enterprises in a low-cost manner. However, these sustainability goals should be integrated with conventional production constraints besides the due date, e.g., reasonable labor cost based on work shifts, no production at weekends, and changeovers for different product types. This paper formulates a mixed-integer linear programming model for energy- and labor-cost-aware production scheduling at the unit process level, considering all the aforementioned constraints. A state-based energy model is used to reveal the energy consumption behavior of a process over time. It thus enables fine-grained energy-aware production scheduling. A case study is conducted for a blow molding process in a Belgian plastic bottle manufacturer. The measured power data enables to build an empirical energy model. The production scheduling is performed under real-time electricity pricing data. As a result, production loads are automatically shifted to the optimal periods. The optimal idle mode is automatically selected between production loads (powering off, idle, etc.). A schedule of joint energy cost and labor cost minimization is demonstrated to reduce 12% and 5% of total cost, compared to schedules that minimize energy and labor cost, respectively. In conclusion, although the labor wage is usually higher during periods with lower electricity price, energy and labor costs can be jointly optimized as a single objective to help factories minimize the production expenditure.
Non-contact optical three dimensional liner metrology (2001)

We optically captured the "as-built" liner geometry of NTLX (near term liner experiments) for Shiva Star using ultra-precision ranging lasers. We subsequently verified the resulting digitized geometry against the 3D CAD model of the part. The results confirmed that the Liner contours are within designed tolerances but revealed subtle fabrication artifacts that would typically go undetected. These features included centimeters long waviness and saddle and bulge regions of 1 micron or less in magnitude. The laser technology typically provided 10 micron spatial resolution with /spl plusmn/12 nanometer ranging precision. Atlas liners in the future may have to be diamond turned and will have the centimeter wavelength and 100 angstrom amplitude requirements. The advantages of using laser technology are (1) it avoids surface damage that may occur with conventional contact probes and (2) dramatically improves spatial resolution over CMM, capacitance and inductance type probes. Our work is the result of a perceived future need to develop precision, non-contact, liner inspection techniques to verify geometry, characterize machining artifacts and map wall thickness on delicate diamond turned surfaces. Capturing "as-built" geometry in a non-contact way coupled with part-to-CAD verification software tools creates a new metrology competency for MST-7.
Insulin-like Growth Factor-I Augments Erythropoietin-induced Proliferation through Enhanced Tyrosine Phosphorylation of STAT5 (1998)

Insulin-like growth factor (IGF-I) is known to synergistically stimulate the proliferation of hematopoietic cells in combination with other hematopoietic growth factors. However, the precise mechanism underlying the cooperative effects of IGF-I is unknown. In a human interleukin-3 or erythropoietin (EPO)-dependent cell line, F-36P, IGF-I alone failed to stimulate DNA synthesis but did augment the EPO-dependent DNA synthesis of F-36P cells. The treatment of F-36P cells with a combination of EPO and IGF-I (EPO/IGF-I) was found to enhance EPO-induced tyrosine phosphorylation of STAT5, whereas IGF-I alone did not. Furthermore, c-CIS mRNA expression, one of the target molecules of STAT5, was more effectively induced by EPO/IGF-I than by EPO alone. To examine the mechanisms of the EPO- and EPO/IGF-I-induced proliferation of F-36P cells, we expressed dominant negative (dn) mutants of STAT5 and Ras in an inducible system. The EPO-induced DNA synthesis and the cooperative effect of EPO/IGF-I were significantly inhibited by the inducible expression of dn-STAT5 or dn-Ras. In addition, the inducible expression of dn-Ras abolished the IGF-I-enhanced tyrosine phosphorylation of STAT5. These results suggest that IGF-I may augment EPO-induced proliferation by enhancing tyrosine phosphorylation of STAT5 and raise the possibility that Ras may be involved in the augmentation of STAT5 tyrosyl phosphorylation.
Modified Julia Olefination on Sugar‐Derived Lactones: Synthesis of Difluoro‐exo‐glycals (2014)

Abstract We report the preparation of difluoro‐ exo ‐glycals by gem ‐difluoroolefination of benzylated sugar‐derived lactones using a modified Julia reaction. The addition is highly stereoselective, and the Smiles‐rearrangement–elimination sequence can be carried out under microwave irradiation.
ChemInform Abstract: Regioselective Carbonylation of trans‐Disubstituted Epoxides to β‐Lactones: A Viable Entry into syn‐Aldol‐Type Products. (2013)

Abstract The new two catalysts show high and opposing selectivities in the title reaction.
Use of synchrotron-based radiography to diagnose pulsed power driven wire explosion experiments (2019)

We describe the first use of synchrotron radiation to probe pulsed power driven high energy density physics experiments. Multi-frame x-ray radiography with interframe spacing of 704 ns and temporal resolution of <100 ps was used to diagnose the electrical explosion of different wire configurations in water including single copper and tungsten wires, parallel copper wire pairs, and copper x-pinches. Such experiments are of great interest to a variety of areas including equation of state studies and high pressure materials research, but the optical diagnostics that are usually employed in these experiments are unable to probe the areas behind the shock wave generated in the water, as well as the internal structure of the exploding material. The x-ray radiography presented here, performed at beamline ID19 at European Synchrotron Radiation Facility (ESRF), was able to image both sides of the shock to a resolution of up to 8 μm, and phase contrast imaging allowed fine details of the wire structure during the current driven explosion and the shock waves to be clearly observed. These results demonstrate the feasibility of pulsed power operated in conjunction with synchrotron facilities, as well as an effective technique in the study of shock waves and wire explosion dynamics.
One Pot Synthesis and Characterization of Alginate Stabilized Semiconductor Nanoparticles (2012)

Uniform and well dispersed metal sulfide semiconductor nanoparticles incorporated into matrices of alginate biopolymer are prepared by using a facile in situ method. The reaction was accomplished by impregnation of alginate with divalent metal ions followed by reaction with thioacetamide. XRD analysis showed that the nanoparticles incorporated in the polymer matrix were of cubic structure with the average particle diameter of 1.8 to 4.8 nm. Field emission scanning electron microscopy and high resolution transmission electron microscopy images indicated that the particles were well dispersed and distributed uniformly in the matrices of alginate polymer. FT-IR spectra confirmed the presence of alginate in the nanocomposite. The crystalline nature and thermal stability of the alginate polymer was found to be influenced by the nature of the divalent metal ions used for the synthesis. The proposed method is considered to be a simple and greener approach for large scale synthesis of uniform sized nanoparticles.
Ethanol production from an industrial feedstock by immobilized Zymomonas mobilis in a fluidized-bed bioreactor (1986)

The utilization of a continuous system to ferment glucose to ethanol offers considerable advantages over the traditional batch technology. The combination of high cell loading and rapid flow rate allows the use of nonsterile feed because free contaminants will be washed out of the system. Operation of a columnar reactor filled with the biocatalyst beads as a fluidized - bed reactor will minimize mass transfer resistances and channeling and allow improved disengagement of the gas product, CO/sub 2/. Zymomonas mobilis has been sown to have a higher specific conversion rate and to be more efficient at ethanol fermentation than the conventional Saccharomyces cerevisiae. The response of Z. mobilis to typical unrefined industrial feedstocks, particularly the supplemental nutrients, was unknown and might be a stumbling block to commercialization. Z. mobilix, immobilized in kappa-carrageenan beads has been shown in our laboratory to assimilate and to convert industrial feedstocks as well as the laboratory medium. 4 refs., 2 figs., 1 tab.
Innate Secretory Immunity in Response to Laboratory Stressors That Evoke Distinct Patterns of Cardiac Autonomic Activity (2003)

Stress-induced modulation of innate secretory immunity may be a contributing factor in the observed relationship between stress and susceptibility to infectious diseases. We further propose a more differentiated approach to acute stress by distinguishing among stressors with distinct autonomic nervous system effects.
Use of resealed erythrocytes as delivery system for C-reactive protein (CRP) to generate macrophage-mediated tumoricidal activity. (1987)

We have shown previously in several mouse tumor systems that multilamellar vesicles (MLV) are an effective delivery system for generation of macrophage-mediated tumoricidal activity by C-reactive protein (CRP). Here we show that resealed erythrocyte ghosts (red cell ghosts, RCG) can function in the same manner. CRP associated with red cell ghosts (CRP-RCG) inhibited established lung metastases of T241 fibrosarcoma in C57B1/6J mice. The degree of inhibition was comparable to that observed with CRP-MLV. In other experiments, peritoneal exudate cells, obtained from mice pretreated with CRP-RCG i.p., inhibited growth and pulmonary metastases of T241 tumor in the Winn neutralization assay. Similar results were obtained with MCA-38 colon carcinoma in the Winn assay. These studies indicate that erythrocytes deserve consideration as another delivery system for biological response modifiers.