gebhart/patrepeval huggingface dataset:
Diffraction tomography of strain (2015)

We consider whether it is possible to recover the three dimensional strain field tomographically from neutron and x-ray diffraction data for polycrystalline materials. We show that the distribution of strain transverse to a ray cannot be deduced from one diffraction pattern accumulated along that path, but that a certain moment of that data corresponds to the transverse ray transform of the strain tensor and so may be recovered by inverting that transform given sufficient data. We show that the whole strain tensor can be reconstructed from diffraction data measured using rotations about six directions that do not lie on a projective conic. In addition we give an inversion formula for complete data for the transverse ray transform. We also show that Bragg edge transmission data, which has been suggested for strain tomography with polychromatic data, cannot provide the strain distribution within the material but only the average along the ray path.
Multidimensional Planar Chromatography (2001)

This chapter contains sections titled: Introduction Two-Dimensional or Multidimensional Planar Chromatography? Two-Dimensional Development on Single Layers Methods for the Selection of Appropriate Mobile Phases Two-Dimensional Development on Bilayers Multiple Development in One, Two or Three Dimensions Multiple Development in One Direction Multiple Development in Two Directions Multiple Development in Three Directions Coupled Layers with Stationary Phases of Decreasing Polarity Grafted Planar Chromatography Serially Connected Multilayer Forced-Flow Planar Chromatography Combination of Multidimensional Planar Chromatographic Methods Coupling of PC with other Chromatographic Techniques Further Considerations
Mediated electrochemical oxidation as an alternative to incineration for mixed wastes (1995)

Mediated Electrochemical Oxidation (MEO) is an aqueous process which oxidizes organics electrochemically at low temperatures and ambient pressures. The process can be used to treat mixed wastes containing hazardous organics by destroying the organic components of the wastes. The radioactive components of the wastes are dissolved in the electrolyte where they can be recovered if desired, or immobilized for disposal. The process of destroying organics is accomplished via a mediator, which is in the form of metallic ions in solution. At Lawrence Livermore National Laboratory (LLNL) we have worked with worked with several mediators, including silver, cobalt and cerium. We have tested mediators in nitric as well as sulfuric acids. We have recently completed extensive experimental studies on cobalt-sulfuric acid and silver-nitric acid systems for destroying the major organic components of Rocky Flats Plant combustible mixed wastes. Organics tested were: Trimsol (a cutting oil), cellulose (including paper and cloth), rubber (latex), plastics (Tyvek, polyethylene and polyvinyl chloride) and biomass (bacteria). The process was capable of destroying almost all of the organics tested, attaining high destruction efficiencies at reasonable coulombic efficiencies. The only exception was polyvinyl chloride, which was destroyed very slowly resulting in poor coulombic efficiencies. Besides the process development work mentioned above, we are working on the design of a pilot-plant scale integrated system to be installed in the Mixed Waste Management Facility (MWMF) at LLNL. The system will also be completely integrated with upstream and downstream processes (for example, feed preparation, off-gas and water treatment, and final forms encapsulation). The conceptual design for the NEO-MWMF system has been completed and preliminary design work has been initiated. Demonstration of the process with low-level mixed wastes is expected to commence in 1998.
A practical model for hair mutual interactions (2002)

Hair exhibits strong anisotropic dynamic properties which demand distinct dynamic models for single strands and hair-hair interactions. While a single strand can be modeled as a multibody open chain expressed in generalized coordinates, modeling hair-hair interactions is a more difficult problem. A dynamic model for this purpose is proposed based on a sparse set of guide strands. Long range connections among the strands are modeled as breakable static links formulated as nonreversible positional springs. Dynamic hair-to-hair collision is solved with the help of auxiliary triangle strips among nearby strands. Adaptive guide strands can be generated and removed on the fly to dynamically control the accuracy of a simulation. A high-quality dense hair model can be obtained at the end by transforming and interpolating the sparse guide strands. Fine imagery of the final dense model is rendered by considering both primary scattering and self-shadowing inside the hair volume which is modeled as being partially translucent.
Reasoning about embryos, cloning and stem cells (2003)

Malcolm Parker is right to insist that the ethical issue at the heart of the debate about embryonic stem cells concerns moral status of a human embryo. Is it, or is it not, an entity to whom we owe the kind of respect that excludes deliberately destroying it? And he is right that both 'sides' to the debate sometimes obfuscate that issue. If a human embryo is the kind of entity that is a limit to our will, then discussions about the relative therapeutic potential of adult v embryonic stem cells cannot reasonably arise. So his frustration with both 'sides' is understandable.
Utilization of Ventilation Air Methane as a Supplementary Fuel at a Circulating Fluidized Bed Combustion Boiler (2008)

Ventilation air methane (VAM) accounts for 60-80% of the total emissions from coal mining activities in China, which is of serious greenhouse gas concerns as well as a waste of valuable fuel sources. This contribution evaluates the use of the VAM utilization methods as a supplementary fuel at a circulating fluidized bed combustion boiler. The paper describes the system design and discusses some potential technical challenges such as methane oxidation rate, corrosion, and efficiency. Laboratory experimentation has shown that the VAM can be burnt completely in circulated fluidized bed furnaces, and the VAM oxidation does not obviously affect the boiler operation when the methane concentration is less than 0.6%. The VAM decreased the incomplete combustion loss for the circulating fluidized bed combustion furnace. The economic benefit from the coal saving insures that the proposed system is more economically feasible.
Experimental and numerical study of lithium niobate photonic crystal cavities - Application for gas sensing (2010)

International audience
A Distributed File System over Heterogeneous SaaS Storage Platforms (2014)

Nowadays, thanks to the massive usage of the Cloud, different providers offer storage as a service solutions. Each of these solutions is characterized by different storage capacity and features. They are also offered according to various business models, typically, users can choose between free plans (with a limited amount of space) and paid plans. Free plans users, when the storage capacity lowers, tend to subscribe to new free plans from other providers, thus increasing the so called data fragmentation. This phenomenon heavily increases the file management complexity. This paper proposes a solution to the data fragmentation problem, by describing an innovative approach which allows to deploy a distributed file system on top of different SaaS storage accounts, offered by different providers. This approach, not only lowers the complexity of data management by providing a single transparent storage solution to the user, but it is also able to provide features like full-text search, file classification and categorization, data analytics (MapReduce) on top of these SaaS storage accounts. Furthermore, this approach proposes a new way to address data privacy and security issues, typically connected to SaaS storage accounts.
16 Pollen Allergens Differ From Nonallergenic Pollen Proteins by Their Lower Extent of Evolutionary Conservation (2012)

BACKGROUND: Pollen contains hundreds of different proteins. However, only a small fraction of them have been identified to be allergenic. We aimed to test the hypothesis that most pollen proteins are non-allergenic due to their high extent of sequence conservation among non-related species. METHODS: Data on the composition of pollen proteomes of birch (Betula pendula), pellitory (Parientaria judaica) and timothy grass (Phleum pratense) were obtained from the literature. Sequences were downloaded from UniProt and manually classified into allergens and non-allergens. Complete proteome sequences of 3 dicotyledonous species (Arabidopsis thaliana, Populus trichocarpa and Vitis vinifera), 2 monocotyledons (Oryza sativa subsp. japonica and Zea mays) and one moss (Physcomitrella patents) were downloaded from ENSEMBL Plants. Sequences of pollen proteins were compared to these proteomes by using BLAST and the hits yielding the highest sequence identity recorded taking into account only sequence alignments at least 40 residues in length. The distributions of maximum sequence identities of allergens and non-allergens from each species were compared using the Mann-Whitney test. RESULTS: Allergens from birch and pellitory pollen were significantly (P < 0.001) less similar to proteins from monocots than non-allergenic pollen proteins. Median sequence identities to the nearest rice and maize homologues were 49 and 52% for birch allergens, 86 and 85% for birch non-allergens, 37 and 37% for pellitory allergens, and 87 and 89% for pellitory non-allergens. Similarly, timothy grass pollen allergens were significantly (P < 0.0001) less similar to dicot proteins than non-allergenic pollen proteins. Median sequence identities to the nearest homologues were 43 to 44% for allergens and 81 to 83% for non-allergens. A comparison of all 3 pollen proteomes to sequences from the moss P. patens yielded similarly significant differences. CONCLUSIONS: Pollen allergens belong to evolutionary less conserved protein families than non-allergenic pollen proteins. The continual exposure of the human immune system to nearly identical and hence highly cross-reactive conserved proteins from multiple pollen and plant food species most likely leads to the induction of immunological tolerance rather than allergic sensitization.
Antibody to AP1B Adaptor Blocks Biosynthetic and Recycling Routes of Basolateral Proteins at Recycling Endosomes (2007)

The epithelial-specific adaptor AP1B sorts basolateral plasma membrane (PM) proteins in both biosynthetic and recycling routes, but the site where it carries out this function remains incompletely defined. Here, we have investigated this topic in Fischer rat thyroid (FRT) epithelial cells using an antibody against the medium subunit micro1B. This antibody was suitable for immunofluorescence and blocked the function of AP1B in these cells. The antibody blocked the basolateral recycling of two basolateral PM markers, Transferrin receptor (TfR) and LDL receptor (LDLR), in a perinuclear compartment with marker and functional characteristics of recycling endosomes (RE). Live imaging experiments demonstrated that in the presence of the antibody two newly synthesized GFP-tagged basolateral proteins (vesicular stomatitis virus G [VSVG] protein and TfR) exited the trans-Golgi network (TGN) normally but became blocked at the RE within 3-5 min. By contrast, the antibody did not block trafficking of green fluorescent protein (GFP)-LDLR from the TGN to the PM but stopped its recycling after internalization into RE in approximately 45 min. Our experiments conclusively demonstrate that 1) AP1B functions exclusively at RE; 2) TGN-to-RE transport is very fast and selective and is mediated by adaptors different from AP1B; and 3) the TGN and AP1B-containing RE cooperate in biosynthetic basolateral sorting.
Synthesis and pKa determination of new enantiopure dimethyl‐substituted acridino‐crown ethers containing a carboxyl group: Useful candidates for enantiomeric recognition studies (2017)

New enantiopure dimethyl-substituted acridino-18-crown-6 and acridino-21-crown-7 ethers containing a carboxyl group at position 9 of the acridine ring [(S,S)-8, (S,S)-9, (R,R)-10] were synthesized. The pK<sub>a</sub> values of the new crown ethers [(S,S)-8, (S,S)-9, (R,R)-10] and of an earlier reported macrocycle [(R,R)-2] were determined by UV-pH titrations. Crown ether (S,S)-8 was attached to silica gel by covalent bonds and the enantiomeric separation ability of the newly prepared chiral stationary phase [(S,S)-CSP-12] was studied by high-performance liquid chromatography (HPLC). Homochiral preference was observed and the best separation was achieved for the enantiomers of 1-NEA. Ligands (S,S)-9 and (R,R)-10 are precursors of enantioselective sensor and selector molecules for the enantiomers of protonated primary amines, amino acids, and their derivatives.
Expression of endothelin 1 and endothelin A receptor in ovarian carcinoma: evidence for an autocrine role in tumor growth. (1999)

In the present study, we have investigated the expression of endothelin 1 (ET-1) and the ET(A) receptor (ET(A)R) and ET(B) receptor (ET(B)R) in primary (n = 30) and metastatic (n = 8) ovarian carcinomas and their involvement in tumor growth. By reverse transcription-PCR and Northern blot analysis, we detected ET-1 mRNA in 90% of primary and 100% of metastatic ovarian carcinomas. ET-1 mRNA expression was significantly higher in tumors than in normal ovarian tissues (n = 12; P < 0.01). ET(A)R mRNA was also detected in 84% of the carcinomas examined, whereas ET(B)R mRNA was expressed in 50% of the tumors. The in vivo presence of mature ET-1 and ET(A)R was confirmed by immunohistochemistry, demonstrating a higher expression in primary and metastatic cells. Ten primary cultures of ovarian tumors secreted ET-1 and were positive for ET-1 and ET(A)R mRNA, whereas only 40% expressed ET(B)R mRNA. Radioligand binding studies showed that ET-1-producing cells also expressed functional ET(A)R, whereas no specific ET(B)R could be demonstrated. ET-1 stimulated dose-dependent [3H]thymidine incorporation and enhanced the mitogenic effect of epidermal growth factor. The ET(A)R-selective antagonist BQ 123 strongly inhibited ET-1-stimulated growth and substantially reduced the basal growth rate of unstimulated cells, whereas the ET(B)R-selective antagonist BQ 788 had no effect. In conclusion, the present data demonstrate a novel mechanism in the growth control of ovarian carcinoma in vivo mediated by the ET-1 autocrine loop that selectively occurs via the ET(A)R.
Optimal dose of oral omeprazole for maximal 24 hour decrease of intragastric acidity. (1984)

In a series of 59 experiments in nine duodenal ulcer patients, 24 hour intragastric acidity was measured before, during, and after treatment with daily oral omeprazole. Omeprazole 10, 20, and 30 mg/day for one week caused a 37, 90, and 97% decrease of 24 hour intragastric acidity, respectively. No further decrease of acidity was observed when the dose of omeprazole was doubled to 60 mg/day, or after a second week of treatment with 30 mg/day. One week after stopping treatment with omeprazole (14 doses) there was a significant 26% decrease of 24 hour intragastric acidity, with full recovery seven weeks later. Fasting plasma gastrin concentration was significantly raised during treatment with all doses of omeprazole. Omeprazole 30 mg/day is the optimal dose for a maximal decrease of 24 hour intragastric acidity in duodenal ulcer patients.
ChemInform Abstract: Studies with Functionally Substituted Heteroaromatics: A Novel Route for the Synthesis of 1‐Aryl‐6‐oxopyridazinones, 1‐Arylpyridazine‐6‐ imines and 1‐Aryl‐6‐imino‐4‐pyridazinals. (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
An argumentation based approach for practical reasoning (2006)

We build on recent work on argumentation frameworks for generating desires and plans. We provide a rich instantiation of Dung's abstract argumentation framework for (i) generating consistent desires; and (ii) generating consistent plans for achieving these desires. This is done through three distinct argumentation frameworks: one (now standard) for arguing about beliefs, one for arguing about what desires the agent should adopt, and one for arguing about what plans to intend in order to achieve the agent's desires. More specifically, we refine and extend existing approaches by providing means for comparing arguments based on decision-theoretic notions (cf. utility). Thus, the worth of desires and the cost of resources are integrated into the argumentation frameworks and taken into account when comparing arguments.
Performance of commercial methods for linezolid susceptibility testing of Enterococcus faecium and Enterococcus faecalis (2020)

Non-automated methods (Sensititre and UMIC) and, to a lesser extent, gradient strip Etest appear to show an acceptable correlation with the BMD reference method for the detection of isolates with low MICs of linezolid after prolonged incubation.
Oxidation of Bilirubin Produces Compounds that Cause Prolonged Vasospasm of Rat Cerebral Vessels: A Contributor to Subarachnoid Hemorrhage–Induced Vasospasm (2002)

The authors have previously shown that bilirubin-oxidation products (BOXes) are present in CSF of subarachnoid hemorrhage patients with vasospasm, and that BOXes cause vasoconstriction in vitro. This study determined whether BOXes cause vasospasm in vivo. Identical volumes of either lysed blood or standardized amounts of BOXes were injected into the cisterna magna of adult rats. BOX injections caused 6 of 10 rats to die within 10 minutes, whereas 12 of 12 rats survived for 24 hours after blood injections. The mechanism for this significant (P < or = 0.01) increase in mortality was unclear. To directly test whether BOXes produced vasospasm, a cranial window technique was used. Application of 20 microL of 10-micromol/L bilirubin had little effect on the vessels. However, application of BOXes produced marked, dose-dependent small artery and arteriole vasospasm that approached a 90% decrease in diameter by 40 minutes after application in some vessels, and persisted for at least 24 hours. To determine if BOX-mediated vasospasm led to cortical injury, histology and immunocytochemistry were performed on animals that survived for 24 hours. There was a BOX-related stress protein response for HSP25 and HSP32 (HO-1) without evidence of infarction. The finding that the BOXes produce vasospasm of cerebral vessels in vivo, in conjunction with BOXes being found in CSF of vasospasm patients, supports our hypothesis that BOXes contribute to or cause cerebral vasospasm after subarachnoid hemorrhage.
Functional mapping of human sensorimotor cortex with electrocorticographic spectral analysis. I. Alpha and beta event- related desynchronization (1998)

Human scalp EEG studies have shown that event-related desynchronization (ERD) in the alpha (8-13 Hz) and beta (15-25 Hz) bands may be used to detect functional activation of sensorimotor cortex. However, in most previous studies somatotopy has not been examined in detail and brief, self-paced movements, focusing on the planning of motor output, have been used. We recorded electrocorticographic (ECoG) signals in five clinical subjects during a visual-motor decision task that was designed to activate the representations of different body parts in sensorimotor cortex. To focus more on execution of motor output than on its planning, subjects were instructed to make sustained isometric muscle contractions in different body parts (tongue protrusion, fist-clenching or foot dorsiflexion) in response to randomized visual stimuli depicting each action. ECoG spectral analysis utilized a mixed-effects analysis of variance model in which within-trial temporal dependencies were taken into account, and the magnitude and statistical significance of alpha and beta ERDs were mapped onto a surface rendering of each subject's brain MRI. Cortical electrical stimulation was performed in all subjects for clinical purposes, and the resulting maps of sensorimotor function were compared with those generated by ECoG spectral analysis. During the early phases of the motor responses, alpha ERD commonly occurred in a diffuse spatial pattern that was not somatotopically specific. During the late phases, the spatial pattern of alpha ERD usually became more focused and somatotopically specific. Maps of alpha ERD were closer to cortical stimulation maps when alpha ERD was sustained throughout the late phases of the motor responses. Thus, the topography of alpha ERD more resembled traditional somatotopy when its temporal profile approximated that of the motor response. The topography of beta ERD was often more discrete and somatotopically specific than that of alpha ERD, but beta ERD was often transient and sometimes absent. Sometimes, unilateral limb movement produced sustained alpha and beta ERD over bilateral sensorimotor cortices, with overlapping patterns for different body parts. The topographical spread of alpha ERD beyond expected functional-anatomical boundaries during early (and sometimes late) phases of motor responses invites a re-examination of traditional assumptions about sensorimotor functional neuroanatomy, as well as the role of alpha ERD as an index of cortical activation. We agree with others that the somatotopic representations of different body parts overlap more than previously thought. Also, unilateral limb movements may be associated with both contralateral and ipsilateral activation of sensorimotor cortex. We conjecture that alpha ERD may reflect activity within a broad synaptic network with distributed cortical representations.
Microstructured media for nonlinear optics: materials, devices, and applications (1996)

Summary form only given. This tutorial will review basic ideas of quasi phase matching (QPM) nonlinear optics, characteristics of available microstructured media, and recent device results in QPM bulk materials; and waveguide SHG, DFG, and OPOs. Opportunities in novel microstructured materials and in applications beyond sources of coherent radiation will also be discussed.
Investigation of the dependence of noise characteristics of SPAD on the gate parameters in sine-wave gated single-photon detectors (2021)

In this paper, we have investigated a self-developed sine wave gated (SWG) single-photon detector (SPD) for 1550 nm wavelength primary for quantum key distribution (QKD) usage. We have investigated different gate parameters` influence on the SPD`s noise characteristics. We have admitted that with an increase of gating voltage and constant value of quantum efficiency (QE), the dark count rate (DCR) decreases. There have been made some recommendations to improve SPD`s and whole QKD device's characteristics based on these observations. There have been discovered the quick rise of the DCR value with the increase of gating voltage above some certain value and this value was different for different detectors. It has been shown that universal empirical dependence compilation to connect control and operational parameters of SPD is a non-trivial task.