gebhart/patrepeval huggingface dataset:
Changing Orders—Primary and Secondary Membrane Transporters Revised (2004)

Members of the major facilitator or ATP-binding cassette superfamily (MFS or ABC) utilize electrochemical gradients or the hydrolysis of ATP to drive up-hill transport across membranes (see figure). Remarkably, their structures and potential transport mechanisms showed several intriguing similarities; this suggests that ATP-driven transporters have evolved from gradient-driven transporters by the acquisition of cytosolic energy-coupling systems.
Aerosol Fluorescence Spectrum Analyzer for Rapid Measurement of Single Micrometer-Sized Airborne Biological Particles (1998)

ABSTRACT We report the operation of an aerosol analyzer capable of measuring the fluorescence spectra of single micrometer-sized bioaerosol particles as they flow through the instrument. Particles entrained in an airstream initially traverse a cw (continuous wave) (488 nm) “trigger” laser beam where their elastic scattering and total fluorescence is measured with photomultipliers. When the elastic scattering and/or fluorescence signals exceed preset levels, a 266 nm UV “probe” laser is triggered to fire and illuminate preselected particles downstream from the trigger laser. The UV laser-excited spectra of particles are measured with the instrument's image-intensified CCD detector that is gated to be on when the probe laser fires. We demonstrate the ability of the instrument to capture the fluorescence spectra of single micrometer-sized airborne biological particles. Such spectra should be useful in differentiating between biological and nonbiological aerosols and in partially characterizing airborne biological particles.
Using Deep Learning to Extract Scenery Information in Real Time Spatiotemporal Compressed Sensing (2018)

One of the problems of real time compressed sensing system is the computational cost of the reconstruction algorithms. It is especially problematic for close loop sensory applications where the sensory parameters needs to be constantly adjust to adapt to a dynamic scene. Through a preliminary experiment with MNIST dataset, we showed that we can extract some scene information (object recognition, scene movement direction and speed) based on the compressed samples using a deep convolutional neural network. It achieves 100% percent accuracy in distinguishing moving velocity, 96.22% in recognizing the digit and 90.04% in detecting moving direction after the code images are re-centered. Even though the classification accuracy drops slightly compared to using original videos, the computational speed is two time faster than classification on videos directly. This method also eliminates the need for sparse reconstruction prior to classification.
A Bacteriocidal Additive for Pyelographic Media (1955)

No AccessJournal of Urology1 Oct 1955A Bacteriocidal Additive for Pyelographic Media Russell B. Roth, Anthony F. Kaminsky, and Elmer Hess Russell B. RothRussell B. Roth More articles by this author , Anthony F. KaminskyAnthony F. Kaminsky More articles by this author , and Elmer HessElmer Hess More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)67317-8AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail © 1955 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByKim S (2018) New Apparatus for Continuous Irrigation and Drainage of Urinary TractJournal of Urology, VOL. 82, NO. 5, (622-624), Online publication date: 1-Nov-1959.Kim S (2018) A New Device for Continuous Bladder IrrigationJournal of Urology, VOL. 81, NO. 2, (330-331), Online publication date: 1-Feb-1959.Bloom J and Richardson J (2018) The Usefulness of a Contrast Medium Containing an Anti-Bacterial Agent (Retrografin) for Retrograde PyelographyJournal of Urology, VOL. 81, NO. 2, (332-334), Online publication date: 1-Feb-1959.Dean A, Lattimer J and McCoy C (2018) The Standardized Columbia University CystogramJournal of Urology, VOL. 78, NO. 5, (662-668), Online publication date: 1-Nov-1957.Quilter T (2018) The Use of Neomycin as a Cold Sterilizing AgentJournal of Urology, VOL. 77, NO. 5, (769-770), Online publication date: 1-May-1957. Volume 74Issue 4October 1955Page: 563-566 Advertisement Copyright & Permissions© 1955 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Russell B. Roth More articles by this author Anthony F. Kaminsky More articles by this author Elmer Hess More articles by this author Expand All Advertisement PDF DownloadLoading ...
Performance evaluation of an IEEE 802.15.4 cognitive radio link in the 2360-2400 MHz band (2011)

In this paper, we analyze the performance of an IEEE 802.15.4 radio link in the 2360-2400 MHz band to support the ongoing Medical Body Area Network (MBAN) standardization activities in IEEE 802.15. There has been a lot of interest recently in opening the 2360-2400 MHz band for secondary allocations to promote MBAN innovations by providing a spectrum with less interference. In this work, we characterize the primary services in this band, focusing on Electronic News Gathering/Outside Broadcasting (ENG/OB) and Aeronautical Mobile Telemetry (AMT) systems. We study the performance in terms of the Packet Error Rate (PER) of an 802.15.4 MBAN radio link implemented on a Universal Software Radio Peripheral 2 (USRP2), in the presence of interference from these systems. A cognitive radio approach is proposed by implementing a spectrum sensing engine based on energy detection on USRP2. Our measurement results show an improvement in the performance of the radio along with primary user protection. In addition, an analytical expression for the packet error rate of the MBAN radio link with spectrum sensing is provided for a given Primary User (PU) activity, which matches well with the measured performance results.
Synthesis of (±)-trans-2,5-Diisopropylborolane (2001)

The cyclic hydroboration of 2,7-dimethyl-2,6-octadiene (6) was studied. It was found that the stereochemical outcome of the reaction was dependent upon the solvent, temperature, time and the nature of the borane reagent. Pure racemic trans-2,5-diisopropylborolane (14) was isolated following selective complexation of the cis-2,5-diisopropylborolane (15) with 1-(2-hydroxyethyl)-pyrrolidine.
Donor Wound Satisfaction After Living Donor Liver Transplantation in the Era of Pure Laparoscopic Donor Hepatectomy (2018)

Introduction In living donor liver transplantation, as well as the donor's safety, the cosmetic appearance is also important in the patient's quality of life aspect. Pure laparoscopic donor hepatectomy has advantages than conventional donor hepatectomy or laparoscopy-assisted hepatectomy. We analyzed the donor's wound satisfaction with pure laparoscopic hepatectomy compared to the conventional open hepatectomy. Method In all, 138 donors who underwent donor hepatectomy for LDLT from April 2010 to December 2016 were included in the study. Donors were divided into 3 groups based on the type of incision: conventional inverted L incision (n = 70; the L group), upper midline incision (n = 43; the U group), and pure laparoscopy incision (n=25; the P group).We checked questionnaire-derived donor satisfaction with cosmetic appearance. Results Demographics, perioperative outcomes, postoperative complications for donors and recipients, and questionnaire-derived donor satisfaction with cosmetic appearance were compared. The total operative time was longer (P=0.003) in the P group but, the hospital stay were lower than conventional open hepatectomy group (L and U groups) (P = 0.010). The result of questionnaire-derived donor satisfaction in the P group was better than conventional group (L and U groups).(P<0.05) Conclusion Pure laparoscopic donor hepatectomy can provide better results in terms of donor wound satisfaction than conventional donor hepatectomy
Tomotherapeutic megavoltage CT calibration (2002)

A calibration of the University of Wisconsin Tomotherapy Benchtop megavoltage CT (MVCT) system was investigated. It was found that IMVCT values correlate extremely well with electron density and that unlike kilovoltage CT, this correlation is well maintained for higher atomic number materials, and is more robust for different patient sizes and locations. Thus, small improvements in dosimetric calculations should be possible by deriving input images from MVCT as opposed to kVCT, as well as calibrating in terms of electron density, as opposed to physical density.
Improving Liquid Supply Pathways on Graphene Oxide Coated Surfaces for Enhanced Pool Boiling Heat Transfer Performance (2018)

Graphene is a two-dimensional material that possesses excellent thermal properties and thus has gained an enormous attention in the applications of heat transfer. In this work, we demonstrate the enhancement of boiling heat transfer performance on substrate coated with graphene oxide and/or copper composites. The graphene oxide and/or copper composites were introduced on the substrate by two commonly used coating techniques-dip-coating and a two-step electrochemical deposition method. The focus of this paper is to compare the morphologies, surface properties such as wickability and porosity rendered by these coating methods and compare the resultant heat transfer coefficients and critical heat fluxes. The surfaces were characterized by Scanning Electron Microscope (SEM), X-Ray Diffraction (XRD), and Fourier Transform Infrared (FTIR) techniques. Critical Heat Flux of 220 W/cm2 at the wall superheat of 14.8°C was achieved for the highest 2.5% GO-Cu electrodeposited chip, while CHF of 128 W/cm2 at the wall superheat of 13.2°C was achieved for the 5 minutes dip coated test surface.
Discovery of emergent malicious campaigns in cellular networks (2013)

The growth of Smartphones has bridged the telephony/SMS and the IP worlds, and this has resulted in new opportunities for financially motivated attackers. For example, some malicious campaigns in the cellular network aimed at extracting money fraudulently can do so even without any malware. Detecting and mitigating the variety of attacks in cellular network is difficult because they do not necessarily have a fixed 'signature', and new types of campaigns appear frequently. Further complicating matters, detecting a single malicious entity (a domain name, a phone number, or a short code) that is part of a malicious campaign, is usually not very effective, because the attacker simply moves to using another entity in its place. An effective strategy requires detecting all/most elements involved in the campaign at once. In this paper, we describe a system, based on ideas from anomaly detection and clustering, that aims to detect many different families of widespread malicious campaigns in cellular networks. The system reveals an entire campaign as a graph cluster which includes the various entities involved in the campaign and their relationship, such as malware download websites, C&C servers, spammers, etc. Using logs from both SMS and IP portions of the network for millions of users, we detect newly popular entities and cluster them to discover how they are related. By looking for cues of possible malicious behavior from any of the entities in a cluster, we attempt to ascertain whether a detected campaign might be malicious, providing valuable leads to a human analyst. Our system is live and generates daily clusters for human analysts. We provide detailed case studies of real, previously unseen families of malicious campaigns that this system has successfully brought to light.
Physical map of the Bombyx mori DNA containing the gene for silk fibroin. (1978)

A physical map of the DNA containing the gene for silk fibroin was developed from direct hybridization analysis of restriction endonuclease digests of total Bombyx mori DNA using fibroin 125I-mRNA. The orientation of mRNA transcription relative to this map was deduced from the sensitivity of the mRNA coding strand within certain DNA restriction segments to lambda-exonuclease and exonuclease III. The map includes the entire gene coding region (Mr approximately 11 x 10(6)) and large DNA elements which flank the gene at its 5' end (Mr approximately 3 x 10(6)) and 3' end (Mr approximately 6.5 x 10(6)). The coding region is remarkably uniform in its sensitivity to restriction endonucleases. It is completely devoid of sites for most of the enzymes tested, including Hae III, the recognition sequence (d-pG-G C-C) of which might be expected to occur frequently in this large DNA block of 60% G + C content. The fibroin coding region does contain an enormous number of sites for enzymes predicted to have activity from known fibroin mRNA sequences. These results suggeste that the fibroin gene core is a large homogeneously repetitive block of DNA with little evidence for sequence divergence, or the presence of qualitatively different sequences, which might creat other restriction sensitivities. The map also allowed a comparison to be made of the fibroin gene "context" in DNA from tissues either active or inactive in fibroin synthesis.
A Randomized Placebo-Controlled Crossover Trial With Phytoestrogens in Treatment of Menopause in Breast Cancer Patients (2003)

In Brief OBJECTIVE Phytoestrogens are popular in treatment of menopause, although scientific evidence is insufficient as to their efficacy. We studied the effects of daily use of isoflavonoids on climacteric symptoms and quality of life in patients with a history of breast cancer. METHODS Sixty-two postmenopausal symptomatic women were randomized to use either phytoestrogen (tablets containing 114 mg of isoflavonoids) or a placebo for 3 months; the treatment regimens were reversed after a 2-month washout period. Fifty-six women completed the study. Menopausal symptoms were recorded on the Kupperman index and the visual analogue scale, and working capacity and mood changes were assessed via validated questionnaires. In addition, we followed the levels of phytoestrogens, follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol, and sex hormone–binding globulin. Liver enzymes and creatinine were also assessed at each visit. RESULTS The phytoestrogen regimen raised the circulating levels of phytoestrogens (daidzein, genistein, equol) 19- to 106-fold. The Kupperman index was reduced by 4.2 ± 9.6 (mean ± standard deviation) (15.5%) during phytoestrogen use and similarly by 4.0 ± 8.1 (14.7%) during placebo use (P nonsignificant). The quality of life parameters (working capacity, mood changes) were unaffected by phytoestrogen. In addition, the phytoestrogen regimen caused no changes in FSH, LH, estradiol, or sex hormone-binding globulin. Phytoestrogen treatment was well tolerated and caused no changes in liver enzymes, creatinine, body mass index, or blood pressure. Of the 56 women, 25 (44.6%) preferred the phytoestrogen regimen, 15 preferred the placebo (26.8%), and 16 (28.6%) reported no preference (nonsignificant). CONCLUSION Pure isoflavonoids did not alleviate subjective menopausal symptoms in breast cancer patients. Pure isoflavonoids are not effective in alleviating subjectivemenopausal symptoms or improving quality of life in breast cancerpatients.
Photo-induced Nanopatterns in self developing polymer films: A possible application of apertureless SNOM to high density data storage (2003)

International audience
Immunoregulatory role of secretory leukocyte protease inhibitor in allergic asthma (2010)

Results Allergic SLPI transgenic mice showed a significant decrease in airway resistance compared to wild-type mice (6.3 ± 1.1 vs. 8.0 ± 2.1 cm H20 × s/ml, p < 0.001), the same effect was observed with inflammatory cell infiltration, eosinophil percentage (24 ± 1.1% vs. 29 ± 2.3%, p < 0.001), goblet cells (6 ± 1.4 vs. 36 ± 4.0%, p < 0.001) in the lungs and IgE levels (2014.1 ± 309.2 vs. 4173.2 ± 685.6 ng/ml, p < 0.001) in plasma. Allergic SLPI knock-out mice displayed significantly higher values compared to wild-type mice. They include lung resistance (8.6 ± 2.7 vs. 6.6 ± 0.5 cm H20*s/ml, p < 0.001), inflammatory cell influx, eosinophils (36.0 ± 2.7 vs. 29.0 ± 1.5%, p < 0.001), goblet cells (40 ± 4.1 vs. 30 ± 1.4%, p < 0.001), cytokine levels in the lungs (p < 0.05) and plasma IgE levels (3598 ± 204.7 vs. 2763 ± 220.3 ng/ml, p < 0.001). Expression of SLPI decreased inflammation in the lungs, plasma IgE levels, and lung resistance, whereas the ablation of SLPI has the opposite effect. Treatment with resiquimod improved airway resistance and inflammation of the lungs in SLPI knockout and wild type, demonstrating that its effect is independent of the expression of SLPI. Conclusions SLPI plays an immunoregulatory role in the respiratory tract by reducing the inflammatory process and by improving lung physiology in a murine model of acute allergic asthma.
Complete amino acid sequence of a membrane receptor for glycoproteins. Sequence of the chicken hepatic lectin. (1981)

The chicken hepatic lectin is involved in the clearance of glycoproteins from circulation (Kawasaki, T., and Ashwell, G. (1977) J. Biol. Chem. 252, 6536-6543). The complete amino acid sequence of chicken hepatic lectin has been established by analysis of peptides generated by chemical cleavage at methionine or tryptophan residues. Larger BrCN fragments were further digested with trypsin, chymotrypsin, and clostripain. All sequences were determined by automated sequential Edman degradation. Extensive use was made of high performance liquid chromatography in the purification of peptides and identification of phenylthiohydantoin derivatives of amino acids. The complete sequence is: (formula: see text). The stretch of uncharged amino acids from residue 25 to 48 is a possible membrane-interaction region. Carbohydrate is attached to residue 67.
Analytic modeling of neural tissue: II. Nonlinear membrane dynamics (2022)

Computational modeling of neuroactivity plays a central role in our effort to understand brain dynamics in the advancements of neural engineering such as deep brain stimulation, neuroprosthetics, and magnetic resonance electrical impedance tomography. However, analytic solutions do not capture the fundamental nonlinear behavior of an action potential. What is needed is a method that is not constrained to only linearized models of neural tissue. Therefore, the objective of this study is to establish a robust, straightforward process for modeling neurodynamic phenomena, which preserves their nonlinear features. To address this, we turn to decomposition methods from homotopy analysis, which have emerged in recent decades as powerful tools for solving nonlinear differential equations. We solve the nonlinear ordinary differential equations of three landmark models of neural conduction-Ermentrout-Kopell, FitzHugh-Nagumo, and Hindmarsh-Rose models-using George Adomian's decomposition method. For each variable, we construct a power series solution equivalent to a generalized Taylor series expanded about a function. The first term of the decomposition series comes from the models' initial conditions. All subsequent terms are recursively determined from the first. We show rapid convergence, achieving a maximal error of <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mo><</mml:mo> <mml:mn>1</mml:mn> <mml:msup><mml:mrow><mml:mn>0</mml:mn></mml:mrow> <mml:mrow><mml:mo>-</mml:mo> <mml:mn>12</mml:mn></mml:mrow> </mml:msup> </mml:math> with only eight terms. We extend the region of convergence with one-step analytic continuation so that our complete solutions are decomposition splines. We show that this process can yield solutions for single- and multi-variable models and can characterize a single action potential or complex bursting patterns. Finally, we show that the accuracy of this decomposition approach favorably compares to an established polynomial method, B-spline collocation. The strength of this method, besides its stability and ease of computation, is that, unlike perturbation, we make no changes to the models' equations; thus, our solutions are to the problems at hand, not simplified versions. This work validates decomposition as a viable technique for advanced neural engineering studies.
Preparing Students for Effective Explaining of Worked Examples in the Genetics Cognitive Tutor (2011)

This study examines the impact of integrating worked examples into a Cognitive Tutor for genetics problem solving, and whether a genetics process modeling task can help prepare students for explaining worked examples and solving problems.Students participated in one of four conditions in which they engaged in either: (1) process modeling followed by interleaved worked examples and problem solving; (2) process modeling followed by problem solving without worked examples; (3) interleaved worked examples and problems without process modeling; or (4) problem solving alone.Tutor data analyses reveal that process modeling led to faster reasoning and greater accuracy in explaining problem solutions.Process modeling and worked examples together led to faster reasoning in problem solving than did any of the other three conditions.Students in all conditions achieved equivalent problem-solving knowledge, as measured by posttest accuracy, although the tutor results suggest reasoning speed may be a more sensitive measure of learning.
Anatomical, functional and dynamic MRI features of the G144 GBM model developed in NOD-SCID mice (2023)

Preclinical models are needed to study glioblastoma multiforme, the most lethal malignant brain tumor. Human G144-glioblastoma stem cells have been used in in vitro studies but there are few studies in vivo, especially using MRI approaches. We aimed to evaluate in vivo, for the first time to our knowledge, a G144 glioblastoma model by multiparametric-MRI. NOD-SCID mice were orthotopically injected with G144 cells, tumor was characterized by multiparametric-MRI and dynamic contrast enhancement studies. G144 tumors presented heterogeneous imaging pattern compared to other GBM models with higher contrast uptake areas and edema related features.
Minimizing temperature sensitivity of silicon Mach-Zehnder interferometers (2010)

We present a novel design approach for integrated Mach-Zehnder interferometers to minimize their temperature sensitivity and demonstrate, for the first time, near zero spectral shifts with temperature (approximately 0.005 nm/K) in these devices. This could lead to fully CMOS-compatible passively compensated athermal optical filters and modulators.
Morphology and Mechanical Properties of Itaconic Anhydride Grafted Poly(lactic acid) and Thermoplastic Protein Blends (2018)

Abstract Blends between Novatein thermoplastic protein and polylactic acid (PLA) have been prepared by reactive extrusion using itaconic anhydride grafted PLA. At equal proportions of Novatein and PLA, the absence of a compatibilizer formed a dispersed phase morphology of Novatein in PLA and the incorporation of compatibilizer formed a co-continuous morphology. Incorporating PLA in Novatein can improve the tensile strength of Novatein by 42% and the impact strength by 36% at an equal proportion blend (50/50) in the presence of a compatibilizer. Thermal analysis revealed that 50/50 was the phase inversion point, above and below this composition the material behaved similarly. The effect of compatibilizer was evident in wide-angle X-ray scattering. In the absence of compatibilizer three phases were detected: crystalline Novatein, amorphous Novatein, and amorphous PLA phases. With compatibilizer, the blend was moving towards two phases: crystalline Novatein, and an amorphous blend of Novatein and PLA. Itaconic anhydride grafted PLA improved miscibility between Novatein and PLA, and its use can potentially lead to the production of Novatein/PLA foams.