gebhart/patrepeval huggingface dataset:
Prebiotic Potential of Xylooligosaccharides Derived from Corn Cobs and Their In Vitro Antioxidant Activity When Combined with Lactobacillus (2015)

In the present work, the in vitro prebiotic activity of xylooligosaccharides (XOS) derived from corn cobs combined with Lactobacillus plantarum, a probiotic microorganism, was determined. These probiotics exhibited different growth characteristics depending on strain specificity. L. plantarum S2 cells were denser and their growth rates were higher when cultured on XOS. Acetate was found to be the major short-chain fatty acid produced as the end-product of fermentation, and its amount varied from 1.50 to 1.78 mg/ml. The antimicrobial activity of XOS combined with L. plantarum S2 was determined against gastrointestinal pathogens. The results showed that XOS proved to be an effective substrate, enhancing antimicrobial activity for L. plantarum S2. In vivo evaluation of the influence of XOS and L. plantarum S2, used both alone and together, on the intestinal microbiota in a mouse model showed that XOS combined with L. plantarum S2 could increase the viable lactobacilli and bifidobacteria in mice feces and decrease the viable Enterococcus, Enterobacter, and Clostridia spp. Furthermore, in the in vitro antioxidant assay, XOS combined with L. plantarum S2 possessed significant 2,2-diphenyl-1- picrylhydrazyl, 2,2'-azino-bis, and superoxide anion radical-scavenging activities, and the combinations showed better antioxidant activity than either XOS or L. plantarum S2 alone.
Wavelet based directional analysis of the gravity field: evidence for large-scale undulation (2012)

M. Hayn,1 I. Panet,2,3 M. Diament,3 M. Holschneider,1 M. Mandea4 and A. Davaille5 1Institute for Mathematics, University of Potsdam, Am Neuen Palais 10, 14469 Potsdam, Germany. E-mail: hayn@math.uni-potsdam.de 2Institut National de l’Information Geographique et Forestiere (formerly Institut Geographique National), Laboratoire de Recherche en Geodesie, GRGS, ENSG, 6/8, av. Blaise Pascal, Cite Descartes, Champs/Marne, 77455Marne-la-Vallee Cedex 2, France 3Institut de Physique du Globe de Paris (IPGP, Sorbonne Paris Cite, UMR 7154 CNRS, Universite Paris Diderot), Bat. Lamarck, Case 7011, 35, rue Helene Brion, 75205 Paris Cedex 13, France 4Centre National d’Etudes Spatiale, 2, place Maurice Quentin, 75039 Paris, France 5Laboratoire FAST (CNRS/Univ. P-Sud/UPMC) Batiment 502, rue du Belvedere, Campus Universitaire, 91405 Orsay, France
Repetitive Transcranial Magnetic Stimulation in Augmentation of Antidepressant Drugs (2007)

Repetitive transcranial magnetic stimulation (rTMS) is a new technology which holds promise as a treatment in neuropsychiatry. Drugs and psychotherapy are inadequate for relieving depressive symptoms in a substantial portion of severely depressed patients. In that patient group, neurostimulation techniques such as rTMS could be useful. Augmentation and combination strategies are commonly employed to address this problem, but there are few randomized, controlled studies to guide treatment choice. This article presents an overview of currently available rTMS techniques for depression, including its use as an add-on therapy reviewing also its efficacy and safety.
One-Pot Multi-Component Synthesis of Polysubstituted Pyridines Using DBU-SiO 2 as a Robust Recyclable Catalyst (2023)

We report an efficient novel route for the synthesis of polysubstituted pyridine derivatives with DBU-SiO2 catalyzed one-pot four-component reaction. This protocol offers a mild condition that which affords a series of new polysubstituted pyridine derivatives with good yields. A plausible mechanism for this process is proposed.
GloCAL: Glocalized Curriculum-Aided Learning of Multiple Tasks with Application to Robotic Grasping (2021)

The domain of robotics is challenging to apply deep reinforcement learning due to the need for large amounts of data and for ensuring safety during learning. Curriculum learning has shown good performance in terms of sample-efficient deep learning. In this paper, we propose an algorithm (named GloCAL) that creates a curriculum for an agent to learn multiple discrete tasks, based on clustering tasks according to their evaluation scores. From the highest-performing cluster, a global task representative of the cluster is identified for learning a global policy that transfers to subsequently formed new clusters, while remaining tasks in the cluster are learnt as local policies. The efficacy and efficiency of our GloCAL algorithm are compared with other approaches in the domain of grasp learning for 49 objects with varied object complexity and grasp difficulty from the EGAD! dataset. The results show that GloCAL is able to learn to grasp 100% of the objects, whereas other approaches achieve at most 86% despite being given 1.5× longer training time.
Brückenkopfkationen des Tricyclo[5.2.1.04, 10]deca‐2,5,8‐triens (Triquinacens) (1976)

Brückenkopf‐Carbeniumionen der Struktur ( 2 ) konnten aus ( 1 ) mit SbF 5 in SO 2 ClF bei −78°C hergestellt werden. Ihre NMR‐Daten zeigen, daß sie nahezu ebene Divinylcarbenium‐Einheiten enthalten. magnified image
Comparison of phytotoxicity and mammalian cytotoxicity of nontrichothecene mycotoxins. (2002)

The phytotoxicity and mammalian cytotoxicity of four nontrichothecene mycotoxins (apicidin, sambutoxin, wortmannin, HC-toxin) were compared. Phytotoxicity was evaluated in terms of electrolyte leakage, growth inhibition, and reduction in chlorophyll content. Based on the parameters evaluated, the relative order of phytotoxicity to duckweed (Lemna pausicostata L.) was wortmannin > HC-toxin > apicidin >> sambutoxin. A 48-hr exposure to 10 microM wortmannin, HC-toxin or apicidin caused electrolyte leakage from duckweed. The IC50 values for growth inhibition and chlorophyll reduction for wortmannin, HC-toxin, and apicidin were 0.2 and 2.6 microM, 15.4 and 12.6 microM, and 27.7 and 45.3 microM, respectively. Based on the parameters measured, a 72-hr exposure to 100 microM sambutoxin was not toxic to duckweed. Kudzu (Pueraria lobata L.) leaf disc assays revealed a similar trend in relative toxicities, but higher mycotoxin concentrations were required to elicit phytotoxic effects compared to duckweed. All four mycotoxins were cytotoxic to four mammalian cell cultures. However, in contrast to plants, wortmannin was the least toxic (IC50 = 10 to 20 microM) and sambutoxin exhibited a high level of toxicity (IC50 = 0.5 to 1 microM).
SU‐GG‐J‐47: Verification of a Deformable Image Registration Algorithm for Head and Neck Cancer Therapy (2010)

Introduction: H&amp;N cancer patients may require frequent CT imaging for re‐planning due to significant anatomical changes to improve dosimetric accuracy. A challenging task is manual delineation of target(s) and normal structures on each image sets acquired on different days. The aim of this study was to verify a Small Deformation Inverse Consistent Linear Elastic (SICLE) deformable image registration for its ability to deformably‐map contours on H&amp;N image sets by comparing them to physician‐drawn contours. Methods and Materials: Six patients with H&amp;N cancer who had frequent CT imaging were selected. GTVs, parotids, cord and brainstem were physican‐drawn on both source and target image sets. Physician‐drawn contours on source image set were deformed by the DVFs to produce deformably‐mapped contours and dose on target images. Differences between the physician‐drawn and deformably‐mapped contours were compared using: “Differences in volumes(Vdiff)”, “differences in center of mass(COMdiff)”, “volume overlap index(VOI)”, “3D‐perpendicular‐distance‐maps”. To evaluate the clinical usefulness, plans were generated based on the physician‐drawn and deformably‐mapped contours. Furthermore, the dose from source image was deformed to target images using the DVFs. Plans were compared for their coverage of physician‐drawn contours. Results: While GTV and NodalGTV VOIs ranged from 0.57 to 0.72 and 0.57 to 0.79 respectively, for parotids, brainstem and cord, it varied from 0.42 to 0.82. Up to 1.7cm and 2.9cm discrepancies were observed in esophagus and cord COM in z direction. Visual comparison of physician‐drawn and deformably‐mapped GTVcontours showed a reasonably well agreement. Dosimetric impact of contour differences was not very significant with &lt;5% differences in PTV D95. Conclusion: SICLE algorithm can produce high quality contours on subsequent H&amp;N image sets. However, manual modification of deformably‐mapped contours may be necessary. Deformably‐mapped contours can be used as a QA tool for inspecting manually‐drawn contours, in addition to reducing or even eliminating the manual contouring workload.
Businesswomen and war metaphors: ‘Possessive, jealous and pugnacious’? (2004)

This paper investigates the metaphors employed for the description of women managers, hypothesising that using the war metaphor in this context reflects the hegemonic masculinity determining business discourse. To test the hypothesis, cognitive metaphor theory in combination with Critical Discourse Analysis is applied to two corpora of business magazine features on executives. Metaphorical expressions used to describe businesswomen are extracted from one corpus, and these expressions are then contrasted with those for businessmen. Moreover, the initial corpus is scanned for alternative metaphors for businesswomen. Findings indicate that metaphorical expressions such as corporate killer are used for first‐ and third‐person reference across genders. Hence, the metaphorical concept businesswomen are warriors and the male prototype it sustains seem pervasive. Moreover, alternatives like businesswomen are cheerleaders/nurturers are not necessarily counter‐discursive as they reproduce the binary gender paradigm characterising hegemonic masculinity.
Letter To The Editor (1970)

The May 1969 issue (Pediatrics, 43: 770) contained an article by Stiehm and Clatanoff on "split products of fibrin in the serum of newborns." The authors discuss the origin of these split products and their possible clinical significance in different pathological conditions in the newborn. At our laboratory we have recently completed a study of the fibrinolytic system in newborns which will be published in Acta paediatrica Scandinavia (accepted for publication July 16, 1969). Our material consists of 207 normal, full term newborns, where blood has been collected by catheterization of the umbilical vein during the first 5 days of life.
Partners in Literacy. A Pilot Attitudinal Survey of Literacy Animators in Tamil Nadu, India. (1989)

Available from British Library Document Supply Centre- DSC:3661.958F(ED--329-770)(microfiche) / BLDSC - British Library Document Supply Centre
Analysis of PGF2α Synthase in Old and New World Species of Leishmania (2008)

Background: Leishmaniasis is characterized by an increase in prostaglandin (PG) levels in the host, which accounts for some of the symptoms of the disease. The molecular mechanisms for the up-regulation of PGs during infection are poorly understood. Identification of the enzymes which catalyze the production of PGs provides a basis for better understanding of PGs’ role in Leishmaniasis. Methods: To investigate the distribution of Prostaglandin F2α (PGF2α) synthase in Leishmania, isolates of L. major, L. donovani, and L. tropica (Old World species) and L. amazonensis, L. braziliensis, L. mexicana, and L. chagasi (New World species) were cultured in vitro. Promastigotes were harvested by centrifugation, washed with Phosphate buffered saline and genomic DNA (gDNA) extracted. The PGF2 α synthase gene was amplified using LmPGFS gene specific primers. 25 μg of total protein was extracted from each species, analyzed on 13% SDS-PAGE gels, and transferred onto an Immun-Blot PVDF membrane Results: We detected the PGF2 α synthase gene in the Old World species (855 bp) but failed to detect it in any of the New World species except for a 2 Kb fragment corresponding to L. braziliensis. The Western Blot analysis detected the PGF2 α synthase enzyme exclusively in the Old World strains. Conclusion: The PGF2α synthase gene was only detected in one of the New World species, and none expressed the synthase enzyme even though most species of New World Leishmania retain the ability to synthesize PGF2α. Evidently, different genes and enzyme systems have evolved to synthesize PGF2α in the Old and New World species. This divergent evolution of the synthase genes in disparate geographical locations may suggest an important role for PGF2α in differing Leishmania vector compatibility between the Old and New Worlds.
Combination of a sulphide semiconductor and an electroactive enzyme: a path for visible light-induced water photo-splitting (2017)

Trabajo presentado en la E-MRS Spring Meeting and Exhibit, celebrada en Estrasburgo del 22 al 26 de mayo de 2017.
Reprogram Murine Epiblast Stem Cells by Epigenetic Inhibitors (2017)

Pluripotent stem cells in the naïve state are highly useful in regenerative medicine and tissue engineering. A robust reprogramming of the primed murine Epiblast Stem Cells (EpiSCs) to naïve pluripotency is feasible via chemical-only approach. This protocol described a method to reprogram murine EpiSCs by MM-401 treatment, which blocks histone H3K4 methylation by MLL1/KMT2A.
Start-Up, Testing, and Performance of the First Bulb-Type Hydroelectric Project in the U.S.A. (1982)

The first bulb-type hydroelectric project in the USA has been completed on the Columbia River near Wenatchee, Washington. This paper discusses the initial start-up, testing and performance of the bulb-type units. Also discussed are operation of the hydraulically operated draft tube gates and their role in the unique sluicing operation.
Development of Methods to Distinguish between Durum/Common Wheat and Common Wheat in Blended Flour Using PCR (2012)

A PCR-based method was developed to distinguish between durum/common wheat and common wheat by leveraging slight differences of DNA sequence in Starch Synthase II (SS II) coded on wheat A, B and D genomes. A primer pair, SS II ex7-U/L, was designed to hybridize with a conserved DNA sequence region found in SS II-A, B and D genes. Another primer pair, SS II-D 1769U/1889L, was constructed to recognize a unique sequence in the SS II-D gene. The target region of SS II ex7-U/L with the size of 114 bp was amplified from durum and common wheat DNA, while no amplification was observed from any cereals other than those in the wheat genus. A DNA fragment with the size of 121 bp was specifically amplified from common wheat with SS II-D 1769U/1889L. In blended flour prepared from wheat and other cereals, the developed PCR system composed of two primer pairs effectively detected durum/common wheat and common wheat. These results suggested that PCR using two primer pairs is useful for detecting common and/or durum wheat in blended flour and could be utilized to ensure accurate food labeling.
The effect of alginate scaffolds on bone healing in defects formed with drilling model in rat femur diaphysis (2023)

Alginate (ALG) is a biocompatible and biodegradable polymer. Mechanical weakness is one of the main problems for the alginate-based scaffolds. Various plasticizer additives or modifications tested to improve the mechanical properties. In the presented study, ALG plasticized with triacetin (TA), and tributyl citrate (TBC) than tested on bone healing. In the presented study, the alginate modified with triacetin or tributyl citrate. In-vitro, and in-vivo efficiency of the scaffolds tested on bone tissue regeneration. Scaffolds fabricated by solvent casting, and physicochemical characterizations performed. Monocytes (THP-1) cultured with scaffolds, and macrophage-released cytokines was determined. In-vivo efficacy of the scaffolds was tested in the rat drill hole model. Alginate and tributyl citrate-modified scaffolds have no cytotoxic effect on osteoblastic cells (MC-3T3). Tributyl citrate modification increased tumor necrosis factor-alpha (TNF-alpha) level but did not increase interleukin -1 beta (IL-1 beta) level. In vivo studies showed that osteoblastic growth was significant in alginate and triacetin-modified scaffolds. However, the best values for osteoclastic activity and osteoid tissue formation seen in the triacetin modification. The results demonstrated that the modified alginate scaffolds were more successful than non-modified alginate scaffolds and can used as long-term bone repairing treatments.
Particle behavior in a rotating ultrasonic waveguide (1985)

An apparatus was designed to allow a suspension of biological cells to be subjected to a well-defined, 160-kHz standing ultrasonic field while being viewed through a stereo microscope. The chamber, which has a square cross section and pressure release walls, acts as a single mode acoustic waveguide. Aqueous metrizamide solution is used to fill the ultrasonic chamber because it has a unique combination of properties including low viscosity, low osmolarity, and high density. The chamber rotates about its axis (whose inclination can be varied) producing the centripetal force necessary to contain the buoyant cells in the axial region. Observations were made on stroboscopically illuminated suspensions both of latex microspheres and of red blood cells. The particles arranged themselves at half-wavelength intervals into axially symmetric formations that became complex and flowering when many particles were present. Some aspects of this behavior are explained by preliminary theory that considers gravitational, rotational, and acoustic radiation forces on the particles. [Work supported by NIH grants GM0729409 (University of Virginia) and GM08209 (University of Vermont).]
Role of cellular factor CTIP2 in transcriptional regulation of the Human T-lymphotropic Virus type 1 (HTLV-1) (2020)

info:eu-repo/semantics/nonPublished
<title>Nonlinear prediction methods for estimation of clique weighting parameters in non-Gaussian image models</title> (1998)

NonGaussian Markov image models are effective in the preservation of edge detail in Bayesian formulations of restoration and reconstruction problems. Included in these models are coefficients quantifying the statistical links among pixels in local cliques, which are typically assumed to have an inverse dependence on distance among the corresponding neighboring pixels. Estimation of these coefficients is a nontrivial task for Non Gaussian models. We present rules for coefficient estimation for edge- preserving models which are particularly effective for edge preservation and noise suppression, using a predictive technique analogous to estimation of the weights of optimal weighted median filters.
The fragility of AES-GCM authentication algorithm. (2013)

Abstract. A new implementation of the GHASH function has been recently committed to a Git version of OpenSSL, to speed up AES-GCM. We identified a bug in that implementation, and made sure it was quickly fixed before trickling into an official OpenSSL trunk. Here, we use this (already fixed) bug as a real example that demonstrates the fragility of AES-GCM’s authentication algorithm (GHASH). One might expect that incorrect MAC tag generation would only cause legitimate message-tag pairs to fail authentication (which is already a serious problem). However, since GHASH is a “polynomial evaluation ” MAC, the bug can be exploited for actual message forgery.
Inhibition of glycosidases by aldonolactones of corresponding configuration. 3. Inhibitors of β-d-galactosidase (1962)

Research Article| February 01 1962 Inhibition of glycosidases by aldonolactones of corresponding configuration. 3. Inhibitors of β-d-galactosidase GA LEVVY; GA LEVVY Search for other works by this author on: This Site PubMed Google Scholar A McALLAN; A McALLAN Search for other works by this author on: This Site PubMed Google Scholar AJ HAY AJ HAY Search for other works by this author on: This Site PubMed Google Scholar Biochem J (1962) 82 (2): 225–232. https://doi.org/10.1042/bj0820225 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Citation GA LEVVY, A McALLAN, AJ HAY; Inhibition of glycosidases by aldonolactones of corresponding configuration. 3. Inhibitors of β-d-galactosidase. Biochem J 1 February 1962; 82 (2): 225–232. doi: https://doi.org/10.1042/bj0820225 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Journal Search Advanced Search This content is only available as a PDF. © 1962 The Biochemical Society1962 Article PDF first page preview Close Modal You do not currently have access to this content.
Polar code interleaver for higher order modulation (2019)

In this paper, we design polar code interleaver for higher order modulation. The interleaver for higher order modulation is designed by combining two permutations. We compare the performance of the proposed interleaver with other interleavers in SC decoder and SCL decoder in 64QAM.
A Protein Encoded by the Herpes Simplex Virus (HSV) Type 1 2-Kilobase Latency-Associated Transcript Is Phosphorylated, Localized to the Nucleus, and Overcomes the Repression of Expression from Exogenous Promoters When Inserted into the Quiescent HSV Genome (2002)

Herpes simplex virus (HSV) is characterized by its ability to establish a latent infection in sensory neurons, from which it can periodically reactivate. The mechanisms of latency, however, remain unclear. The HSV genome is quiescent during latency except for the expression of the latency-associated transcripts (LATs). Although the exact function of the LATs remains obscure, current evidence suggests they are multifunctional and are involved in both establishment of latency and reactivation from latency. The LATs contain several open reading frames (ORFs). One or more of the functions of the LATs could therefore be protein mediated. We have previously reported that deregulated expression of the largest of the HSV type 1 (HSV-1) LAT ORFs ( approximately 274 amino acids) greatly enhances virus growth in cell types that are normally relatively nonpermissive for HSV replication and also that it complements mutations to the immediate-early (IE) gene ICP0 (S. K. Thomas, G. Gough, D. S. Latchman, and R. S. Coffin, J. Virol. 73:6618-6625, 1999). Here we show that LAT ORF expression overcomes the repression of expression from exogenous promoters introduced into the HSV-1 genome which normally occurs in the absence of IE gene expression. To further explore LAT ORF function, we have generated an epitope-tagged LAT ORF, LATmycHis, which forms punctate structures in the infected-cell nucleus reminiscent of the structures formed by ICP0. These are associated with the appearance of a phosphorylated form of the protein and are formed adjacent to, or around the edges of, viral replication compartments. These results provide further evidence that the HSV-1 LAT ORF protein is biologically functional and that the tightly regulated expression of this protein may be important in the wild-type latency phenotype in vivo.
Set-Sweep Programming Pulse for Phase-Change Memories (2006)

This paper presents a non-conventional program pulse approach for phase-change memories (PCMs). The cell programming curve is experimentally evaluated and discussed. The proposed set-sweep program pulse allows compensating for spreads in cell physical parameters. This ensures a better SET condition for marginal cells and adequately narrow SET distributions, which results in improved read margin. Experimental results have been collected from a 8-Mb BJT-selected PCM demonstrator. The effectiveness of the proposed program pulse has been proved by comparing cell distributions obtained on the whole array by means of a conventional SET box and a set-sweep program pulse, respectively.