gebhart/patrepeval huggingface dataset:
Scalable all-optical packet-switching nodes: a dimensioning study (2007)

All-optical label swapping suffers from bad scalability. This paper proposes a new AOLS node design based on wavelength striping. It compares the new design with the original AOLS node via a dimensioning study. (2 pages)
A DNA Microarray-Based Genetic Screen for Nonhomologous End-Joining Mutants in Saccharomyces cerevisiae (2001)

We describe a microarray-based screen performed by imposing different genetic selections on thousands of yeast mutants in parallel, representing most genes in the yeast genome. The presence or absence of mutants was detected by oligonucleotide arrays that hybridize to 20-nucleotide "barcodes." We used this method to screen for components of the nonhomologous end-joining (NHEJ) pathway. Known components of the pathway were identified, as well as a gene not previously known to be involved in NHEJ, NEJ1. Nej1 protein interacts with the amino terminus of LIF1/XRCC4, a recently recognized "guardian of the genome" against cancer.
Preparation of Elemental Cu and Ni Nanoparticles by the Polyol Method: An Experimental and Theoretical Approach (2011)

This paper discusses the relationship between synthesis conditions, crystal morphology, and theoretical modeling of copper and nickel nanoparticles prepared by a modified polyol process. The polyol serves as a solvent, a reducing agent, and a capping agent, and we investigate the role several polyol types play in the nucleation and growth of metallic nanoparticles. The nanoparticles are characterized by transmission electron microscopy (TEM), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS). Our results demonstrate that changing the solvent system from a short chain polyol (ethylene glycol) to a long chain polyol (tetraethylene glycol) greatly affects the resulting morphology of copper nanoparticles. These results suggest that the polyol is playing a major role as an in situ capping agent and that the various polyol chain lengths in-turn result in various particle morphologies by directly altering the nucleation and growth steps. We were also able to use theoretical modeling to investigate the mechanism for growth to better understand the intermediate structure stability. This work presents an alternative approach in investigating the polyol mechanism by using both theoretical and experimental results and opens new insight for the synthesis of metals and alloys by the polyol process.
Promising new precursors for the CVD of gold (1995)

High deposition rates for the CVD of gold at low temperatures are reported. The synthesis and use of methyl(alkyldimethoxyphosphine)gold(I) compounds in the chemical vapor deposition of gold (see Figure) is described, and the precursors are found to be easily handled in air, and to result in comparable deposition rates and higher yields compared to currently used materials. magnified image
Dipole Field Effects On Ion Ejections From A Paul Ion Trap (2012)

Attempts at improving the quality of mass spectra obtained from a Paul trap mass spectrometer prompted an investigation of the effects of additional fields to supplement the primary rf quadrupole trapping field. Reported here are the results of the first in a series of tests that focuses on the application of a single dipole field to augment the trapping and subsequent ejections of ions stored within a Paul trap. Measurements are presented for a fixed quadrupole frequency with varying dipole frequencies. The presence of the dipole field during the quadrupole trapping phase causes ion ejections of single m/z species at discrete dipole frequencies. During the mass analysis phase, the varying dipole frequency produces a complex set of resonant structures that impact ejection time (mass range), as well as mass spectral peak intensity and width.
n-Pentenyl esters facilitate an oxidative alternative to the Ferrier rearrangement. An expeditious route to sucrose (1992)

Ferrier-type reactions can now be carried out under non-acidic conditions by treating 3-n-pentenoyl glycals with iodonium dicollidinium perchlorate whereupon the terminal double bond is chemoselectively activated to furnish an allylic oxo-carbenium ion which reacts at the anomeric position with monosaccharide alcohols to afford 2,3-unsaturated disaccharides in fairly good yields.
Figure S1 from Boosting of Waned Humoral and Cellular Responses to SARS-CoV-2 Variants of Concern Among Patients with Cancer (2023)

&lt;p&gt;S1. Waning serological responses to SARS-CoV-2 vaccination.&lt;/p&gt;
Light Microscopic Observation of Nuclei and Mitotic Chromosomes ofBotrytisSpecies (1989)

The mean number of nuclei in a conidium of B. allii (seven isolates), B. byssoidea (three isolates), and B. cinerea (five isolates) was 1.3-1.5, 5.0-5.1, and 4.0-5.1; respectively, whereas that of B. squamosa (one isolate) was 18.4. The chromosome number was found to be 16 in B. byssoidea, B. cinerea, B. squamosa, and B. tulipae. Seven isolates of B. allii were divided into two groups according to the chromosome number: three isolates had 32 chromosomes, whereas the other four had 16
Electric-field-induced reorientation of ferroelectric micro- and nano-platelets in the nematic liquid crystal (2020)

We demonstrate that ferroelectric layered perovskite Bi3.8Nd0.2Ti3O12 micro-platelets can be reoriented in the nematic liquid crystal by the linear coupling to an external electric field. The electric dipole moment of platelets is perpendicular to the plane of platelets and provides torque that rotates the platelets. The experiments were made in dispersions of ferroelectric platelets in a zero dielectric anisotropy nematic liquid crystal (LC), which excludes the reorientation of the dispersion via the dielectric coupling of a LC. Typical reorientation times for micrometre-size ferroelectric platelets are of the order of 100 ms for 0.5 V/μm applied electric field. The electric dipole moment in the absence of external field is very small and does not contribute to the force between the platelets. This could be either due to very narrow hysteresis loop of the ferroelectric material, or screening of dipolar electric field by ions in the LC. A stable and homogenous dispersion of ferroelectric nano-platelets could not be observed in any range of platelets’ concentration. To create a ferroelectric LC the shape and thickness of the nano-platelets has to be controlled, and the electrostatic screening of dipolar field should be minimised.
Synthesis, Structure–Activity Relationships, and Preclinical Evaluation of Heteroaromatic Amides and 1,3,4-Oxadiazole Derivatives as 5-HT4 Receptor Partial Agonists (2018)

Alzheimer's disease (AD) is a neurodegenerative disorder that has a higher prevalence and incidence in people older than 60 years. The need for improved AD therapies is unmet as the current therapies are symptomatic with modest efficacy. Partial agonists of the 5-HT<sub>4</sub> receptor (5-HT<sub>4</sub>R) offer both symptomatic and disease-modifying treatments as they shift amyloid-precursor-protein (APP) processing from the amyloidogenic pathway to the nonamyloidogenic pathway by activating the α-secretase enzyme. In addition, they also offer symptomatic treatment by increasing levels of the neurotransmitter acetylcholine in the brain. Because of this fascinating dual mechanism of action, several chemical scaffolds having 5-HT<sub>4</sub>R pharmacophores were designed and evaluated. Most of the synthesized compounds showed potent in vitro affinities and in vivo efficacies. Upon analysis of focused structure-activity relationships, compound 4o was identified as a potent 5-HT<sub>4</sub>R partial agonist with favorable ADME properties and good in vivo efficacy. GR-125487, a selective 5-HT<sub>4</sub>R antagonist, attenuated the activity of compound 4o in the novel-object-recognition-test cognition model.
A standard test case suite for two-dimensional linear transport on the sphere: results from a collection of state-of-the-art schemes (2013)

Abstract. Recently, a standard test case suite for 2-D linear transport on the sphere was proposed to assess important aspects of accuracy in geophysical fluid dynamics with a "minimal" set of idealized model configurations/runs/diagnostics. Here we present results from 19 state-of-the-art transport scheme formulations based on finite-difference/finite-volume methods as well as emerging (in the context of atmospheric/oceanographic sciences) Galerkin methods. Discretization grids range from traditional regular latitude-longitude grids to more isotropic domain discretizations such as icosahedral and cubed-sphere tessellations of the sphere. The schemes are evaluated using a wide range of diagnostics in idealized flow environments. Accuracy is assessed in single- and two-tracer configurations using conventional error norms as well as novel diagnostics designed for climate and climate-chemistry applications. In addition, algorithmic considerations that may be important for computational efficiency are reported on. The latter is inevitably computing platform dependent, The ensemble of results from a wide variety of schemes presented here helps shed light on the ability of the test case suite diagnostics and flow settings to discriminate between algorithms and provide insights into accuracy in the context of global atmospheric/ocean modeling. A library of benchmark results is provided to facilitate scheme intercomparison and model development. Simple software and data-sets are made available to facilitate the process of model evaluation and scheme intercomparison.
Adoptive Transfer of JC Virus‐Specific T Lymphocytes for the Treatment of Progressive Multifocal Leukoencephalopathy (2021)

Among other novel treatments, T cell therapy is emerging as a viable treatment option in patients with PML, particularly for those not amenable to restoration of specific immunity. Neurologists should be encouraged to refer PML patients to specialized centers to allow access to this treatment strategy. ANN NEUROL 2021;89:769-779.
Nanoliter Chemistry Combined with Mass Spectrometry for Peptide Mapping of Proteins from Single Mammalian Cell Lysates (1998)

A nanoliter-chemistry station combined with matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry was developed to characterize proteins at the attomole level. Chemical reactions including protein digestion were carried out in nanoliter or subnanoliter volumes, followed by microspot sample deposition of the digest to a MALDI-TOF mass spectrometer. Accurate mass determination of the peptides from the enzyme digest, in conjunction with protein database searching, allowed the identification of the proteins in the protein database. This method is particularly useful for handling small-volume samples such as in single-cell analysis. The high sensitivity and specificity of this method were demonstrated by peptide mapping and identifying hemoglobin variants of sickle cell disease from a single red blood cell. The approach of combining nanoliter chemistry with highly sensitive mass spectrometric analysis should find general use in characterizing proteins from biological systems where only a limited amount of material is available for interrogation.
Study of the detached plasma regime in TFTR using the MIRI far-infrared interferometer (1986)

Plasmas have been formed in the tokamak fusion test reactor (TFTR) which separate completely from the limiter and are called detached plasmas. The physical evidence for the separation from the limiter is that all the ohmic input power is radiated away at the plasma boundary which can be 10→30 cm inside the limiter. The 10-chord multichannel MIRI interferometer system has been used to diagnose this region and follows the formation of the detached state through a MARFE. MIRI indicates that a plasma ∼0.5→1×1013 cm−3 occurs in the region between the luminous boundary and the limiter. This work was supported by U.S. DOE Contract No. DE-AC02-76-CHO-3073.
Data Envelopment Analysis for steel production with the use of Total Material Requirement (2017)

High properties of stainless steels can be achieved by adding alloying elements and/or by structure control through complex heat treatments. Evaluations of such processes have so far been made in terms of the carbon dioxide emissions emitted or the energy consumption, but less attention has been given to resource intensity and “hidden flows”. Using Data Envelopment Analysis (DEA), this study evaluates the efficiency of the environmental impact, characterised through Total Material Requirement (TMR), a measurement of hidden flows, and three properties (two mechanical and one chemical) of the materials obtained after manufacturing. Out of sample of 72 stainless steels it was found that seven (SUS312L, SUS836L, SUS447J1, SUSXM27, SUS410, SUS420F2, and SUS329J4L) showed the highest comparative efficiency, and that, when classifying the sample into four groups, the production of martensitic steels showed the highest efficiency (88%), followed by ferritic and duplex (82.6% each) and lastly austenitic (43.3%).
In vivo measurement of the attenuation coefficient of the sclera and ciliary muscle (2021)

We acquired 1325 nm OCT images of the sclera and ciliary muscle of human subjects. The attenuation coefficients of the sclera and ciliary muscle were determined from a curve fit of the average intensity profile of about 100 A-lines in a region of interest after correction for the effect of beam geometry, using a single scattering model. The average scleral attenuation coefficient was 4.13 ± 1.42 mm<sup>-1</sup> with an age-related decrease that was near the threshold for statistical significance (p = 0.053). The average ciliary muscle attenuation coefficient was 1.72 ± 0.88 mm<sup>-1</sup>, but this value may be an underestimation due to contributions from multiple scattering. Overall, the results suggest that inter-individual variations in scleral attenuation contribute to variability in the quality of transscleral OCT images of the ciliary muscle and the outcome of transscleral laser therapies.
Visualiztion of Viscous Heating in the Earth's Mantle Induced by Glacial Loading (2003)

We have studied the a possible mechanism of transferring gravitational potential energy into viscous heating in the mantle via glacial loading during the ice ages. Shear heating associated with the transient flow occurring over a short timescale on the order of tens of thousand of years can cause a non-negligible amount of heat production in the mantle. We have applied our initial-value approach to the modelling of viscoelastic relaxation of spherical compressible self-gravitating Earth models with a linear viscoelastic Maxwellian rheology. We have focussed on the magnitude of deformations, stress tensor components and corresponding dissipative heating for ice sheets of the size of the Laurentide ice mass and cyclic loading with a fast unloading phase two orders of magnitude less than that associated with mountain building and vertical tectonics.
Matlab Implementation of Reverberation Algorithms (2002)

Abstract In this paper, we present the implementation of different reverberation algorithms in the Matlab programming environment. Matlab is a useful tool to analyze the algorithm's behavior under the signal processing point of view. In addition, the possibility of hearing the results is quite simple and fast. The reverberation algorithms are presented in terms of elementary blocks, and the details of the Matlab implementation of these blocks are depicted. Afterwards, we present the implementation of some of the most representative reverberation algorithms using those elementary blocks. Each reverberation algorithm has been reformulated in terms of their transfer function, in order to fit the Matlab filter function syntax.
Performance of the CEBAF arc beam position monitors (2002)

The first three quarters of the first CEBAF arc have been instrumented with beam position monitors. Thirty-seven monitors (of 450) have been installed and their noise measured. Resolution of 100 /spl mu/m was obtained at the lowest operating current of 1 /spl mu/A. The update time of the system is 1 sec, limited by computer interfacing, with a potential bandwidth of greater than 10 kHz.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Evaluation of dyskerin expression and the Cajal body protein WRAP53β as potential prognostic markers for patients with primary vaginal carcinoma (2021)

Primary vaginal cancer (PVC) is a rare gynaecological malignancy, which, at present, lacks appropriate biomarkers for prognosis. The proteins dyskerin and WD repeat containing antisense to TP53 (WRAP53β), both of which exert their functions in the telomerase holoenzyme complex, have been shown to be upregulated in different cancer types. These proteins have also been proposed as prognostic markers in some types of cancer. The aim of the present study was to examine the expression patterns of dyskerin and WRAP53β in patients with PVC. Moreover, as part of a search for effective biomarkers to evaluate prognosis in PVC, the expression of these two proteins and their potential association with clinical variables and survival were also evaluated. The expression of dyskerin and WRAP53β was assessed in PVC tumour samples from 68 patients using immunohistochemistry. The majority of tumour samples showed low and moderate expression levels of dyskerin. Upregulation of dyskerin in tumour samples was significantly associated with a shorter survival time and a poorer cancer-specific survival rate. WRAP53β was also expressed in most of the cells but was not significantly associated with clinical variables or survival. This study demonstrates that upregulation of dyskerin is significantly associated with poor prognosis. Thus, dyskerin may serve as a promising prognostic marker and a potential putative therapeutic target in PVC.
Active power measurement comparison between analog and digital methods (2013)

The measurement method used in this paper compares the power measurement on analog wattmeter and digital systems. One analyzes, in the first part, the metrological behavior of an electrodynamics wattmeter and in the second part one uses a multifunction measurement numerical method. This method uses tow Hall sensors and an electronic analog multiplication process to adapt the network voltage and current and also the power measurement. Via an interface board of the type CIGAL M23, one acquires directly the normalized power using a statistical measurement method which increases the accuracy. Using an 8255 timer, one measures the phase angle between the voltage and the current load. The intelligent system allows us to measure the phase angle, the active, reactive and apparent power and to identify the load type (inductive or capacitive one). A comparison in the active power was made between the electrodynamics wattmeter and the smart system. The measurement ranges of this power systems are: An input voltage of 220V and a maximum load current of 5A. The accuracy is less than 0.2%.
Semantic based search engine for 3D shapes: design and early prototype implementation (2005)

Searching for 3D resources is gradually becoming one of those intriguing research topics that have the potential to shape how users will access and interact with the internet in the years to come. Search engines like Google Image Search, or the Princeton 3D Model Search Engine, show a glimpse of the potential for 3D searching in the Web. 3D shapes, however, present highly complex and heterogeneous objects, even more so, because of the different semantics that different applications and tools use while dealing with these resources. In the AIM@SHAPE Network of Excellence, one of the main objectives is to deal with the knowledge that is implicit in shapes and to formalize the underlying semantics through the use of ontologies. These ontologies pertain to specific scientific areas related to shape modelling and promote the reusability of domain knowledge. Modelling the semantics of shape objects constitutes a concrete step in developing an effective search mechanism for 3D resources. This mechanism is part of the Digital Shape Workbench infrastructure within AIM@SHAPE and its current state of development is presented in this paper.
Development of lightweight hydrides (1982)

Automotive use of hydrogen as a fuel (energy carrier) is a future option in a world with low petroleum reserves. Hydrogen has a high energy content per pound and produces relatively few emissions when burned. Two basic problems restrict the exercise of that option; methods must be developed to produce hydrogen economically from renewable or solid fossil fuel sources and the need for practical onboard systems to store hydrogen in a safe, dense and relatively lightweight configuration. The authors have concentrated their efforts on the development of the metal hydride approach for hydrogen storage. Metal hydrides can store more hydrogen per unit volume than normal high pressure or even cryogenic hydrogen techniques. Little energy is required to store the hydrogen in the hydride, and high stability at room temperature ensures low losses over long storage periods. Safety features of metal hydride storage are favorable. Because of its low weight and high hydrogen storage densities, modified magnesium alloy-based hydrides appear to offer the greatest potential for automotive storage of hydrogen. Recent experimental and analytical work has been directed toward the optimization of this storage system. Due to the relative stability of MgH/sub 2/, modifications of the form MgMHx (M = metal atom) have been made to decrease the dissociation temperature while retaining high hydrogen capacity. This parameter is crucial since vehicle exhaust will supply the thermal energy to dissociate the hydride in an automobile. System studies indicate that hydride dissociation temperature should be 200/sup 0/C or lower to ensure uninterrupted fuel flow at all driving and idle conditions. This report describes the authors' modifications to magnesium hydride based families of materials.
Leopoldo de Luis (1982)

A 66 year-old man was found to have pointed out a 1-cm tumor shadow, on a chest X-ray film when he underwent a gastrectomy because of advanced gastric cancer. Five months after the operation, edema and proteinuria developed, and a chest X-ray film revealed enlargement of the tumor. There was no sign of recurrence of the gastric cancer. Nephrotic syndrome due to IgA-nephropathy and small cell lung cancer was diagnosed. Chemotherapy (carboplatin and etoposide) was effective against both the lung tumor and the nephrotic syndrome. Small cell lung cancer may have been involved in the pathogenesis of the nephrotic syndrome in this patient.
Prognostic Significance of Circulating Tumor Cells in Non-Small-Cell Lung Cancer Patients: A Meta-Analysis (2013)

The presence of CTCs indicates a poor prognosis in patients with NSCLC. Further well-designed prospective studies are required to explore the clinical applications of CTCs in lung cancer.
Central nervous system involvement as the presenting manifestation of autoimmune rheumatic diseases: an observational study using the American College of Rheumatology nomenclature for neuropsychiatric lupus. (2007)

SLE and APS either primary or secondary to SLE were the most common underlying systemic autoimmune rheumatic diseases, in patients presenting with a neurological event of acute onset. Young adults (< 45 years old) with CVD should undertake screening for SLE/APS.