gebhart/patrepeval huggingface dataset:
Development and evaluation of a glucose analyzer for a glucose controlled insulin infusion system ((Biostator). (1978)

The Glucose-Controlled Insulin Infusion System (Biostator) is a modular, computerized, feedback control system for dynamic control of blood glucose concentrations in diabetics. This on-line glucose analyzer for use with whole blood utilizes a novel enzyme (glucose oxidase)-membrane configuration and an electrochemical cell to measure the H202 generated. The analyzer exhibits both short- and long-range stability, and instrument response and analyte concentration are linearly related over the full range of clinical interest. The response is fast, accurate, and precise, and permits determination of blood glucose within 2 min from the moment the blood leaves the patient. Correlation studies were completed to show the agreement between the Biostator Glucose Analyzer and the FDA's recommended hexokinase/glucose-6-phosphate dehydrogenase procedure on whole blood (e.g., average per cent recovered for 11 concentrations between 250 and 900 mg/liter was: hexokinase, 95.6%, Biostator Analyzer, 95.9%; bias and SDd, respectively, at low, normal, and high glucose values were: 12 and 41 mg/liter at the 500 mg/liter level; 4 and 52 mg/liter at the 1000 mg/liter level, and 4 and 128 mg/liter at the 4000 mg/liter level). No appreciable interference is observed with above-normal concentrations of bilirubin, uric acid, creatinine, sodium salicylate, or dextran. Platelet adhesion, which tends to decrease the useful life of the membrane, has been significantly decreased.
Correction of the cDNA-derived protein sequence of prostatic spermine binding protein: pivotal role of tandem mass spectrometry in sequence analysis (1988)

Spermine binding protein (SBP) is a rat ventral prostate protein that binds various polyamines, and the level of this protein and its mRNA is regulated by androgens. Previously, the cDNA for SBP was cloned and sequenced and an amino acid sequence deduced from the cDNA. Data from cloned and sequenced and an amino acid sequence deduced from the cDNA. Data from partial amino acid sequencing of the purified protein were consistent with the amino acid sequence deduced from the cDNA. However, the amino terminus of the protein was blocked, and therefore, direct protein sequence information confirming the cDNA reading frame of this region could not be obtained by Edman degradation. We have now employed an integrated approach using fast atom bombardment mass spectrometry, tandem mass spectrometry, and conventional sequencing methodologies to establish the amino-terminal sequence of the protein and to identify an amino acid sequence (35 residues) present in the purified protein but missing from the amino acid sequence deduced from cDNA clones for this protein. The missing piece of cDNA corresponds to an exon found in mouse genomic clones for a protein similar to rat SBP. Therefore, the cDNA clones for rat SBP may represent splicing variants that lack the sequence information of one exon. The blocked amino terminus of the protein was identified as 5-oxopyrrolidine-2-carboxylic acid. Mass spectrometry also provided evidence regarding glycosylation of the protein. The first of two potential glycosylation sites clearly carries carbohydrate; the second site is, at most, only partially glycosylated.
Lens Implantation: 30 Years of Progress (1983)

Book reviewsbut conveniently placed in this volume.The last contribution is a genetic survey of a large population with retinitis pigmentosa.It is difficult for the average reader but useful for those concerned with the management of patients with one of this group of disorders.Reports of proceedings are notoriously patchy; this is no exception.It is useful to have this material in one place, yet no one will find every paper of interest.To the reviewer the most important papers were the first 2, and these could easily be overlooked by the majority of ophthalmologists.This is a book for the library, one to dip into if one is an established ophthalmologist, but one to read carefully if one is in training.
Functional Anatomy of the Craniolateral and Caudomedial Bundles of the Caudal Cruciate Ligament in Beagle Dogs (2021)

This study contributes to understanding of the biomechanics and the function of the caudal cruciate ligament, which help to elucidate the pathophysiology of caudal cruciate ligament tear and to develop stifle joint stabilization surgery.
The SAS Image Data Classification with Minimum Error Probability Bayes Classifier (2012)

Due to multipath noise pollution, SAS image consists of two parts : target and noise .They can be described by K + K mixture distribution . How to separate noise data which obey K distribution from the target which also obeys K is a hot topic in SAS image field. This paper used the minimum error probability Bayes classifier to solve this problem, and achieved good results. At the same time, this paper also studied the factors that affect the classification results, such as the absolute value difference of training sample parameters and K distribution parameters.
Trans-generational effects on diapause and life-history-traits of an aphid parasitoid (2019)

Summary Transgenerational effects act on a wide range of insects’ life-history traits and can be involved in the control of developmental plasticity, such as diapause expression. Decrease in or total loss of winter diapause expression recently observed in some species could arise from inhibiting maternal effects. In this study, we explored transgenerational effects on diapause expression and traits in one industrial and one wild strain of the aphid parasitoid Aphidius ervi . These strains were reared under short photoperiod (8:16 h LD) and low temperature (14 °C) conditions over two generations. Diapause levels, developmental times, physiological and morphological traits were measured. Diapause levels increased after one generation in the wild but not in the industrial strain. For both strains, the second generation took longer to develop than the first one. Tibia length and wing surface decreased over generations while fat content increased. A crossed-generations experiment focusing on the industrial parasitoid strain showed that offspring from mothers reared at 14 °C took longer to develop, were heavier, taller with wider wings and with more fat reserves than those from mothers reared at 20 °C (8:16 h LD). No effect of the mother rearing conditions was shown on diapause expression. Additionally to direct plasticity of the offspring, results suggest transgenerational plasticity effects on diapause expression, development time, and on the values of life-history traits. We demonstrated that populations showing low diapause levels may recover higher levels through transgenerational plasticity in response to diapause-induction cues, provided that environmental conditions are reaching the induction-thresholds specific to each population. Transgenerational plasticity is thus important to consider when evaluating how insects adapt to changing environments.
Medical Comorbidity and Rehabilitation Efficiency in Geriatric Inpatients (2001)

Medical comorbidity was a significant predictor of rehabilitation efficiency in geriatric patients. Comorbidity scores >5 were prognostic of poorer rehabilitation outcomes and can serve as an empirical guide in estimating a patient's suitability for rehabilitation. Medical comorbidity predicted both the overall functional change achieved with retabilitation (Functional Independence Measure gains) and the rate at with which those gains were reached (rehabilitation efficiency ratio).
Synthesis of nano-sized C 3 -symmetric 2,4,6-triphenyl-1,3,5- s -triazine and 1,3,5-triphenylbenzene derivatives via the trimerization followed by Suzuki-Miyaura cross-coupling or O-alkylation reactions and their biological evaluation (2009)

Various C(3)-symmetric 2,4,6-triphenyl-1,3-5-s-triazine and 1,3,5-triphenylbenzene derivatives have been prepared using cyclotrimerization, Suzuki-Miyaura cross-coupling and O-alkylation reactions as key steps. The biological activity of O-alkylated triazine derivatives has been studied towards the HeLa cell proliferation. The resulting C(3)-symmetric derivatives can also be useful in materials chemistry.
Polycations sensitize enteric bacteria to antibiotics (1983)

Polymyxin B nonapeptide, a polymyxin B derivative which lacks the fatty acyl part and the bactericidal activity of polymyxin, was shown to sensitize smooth encapsulated Escherichia coli (O18:K1) and smooth Salmonella typhimurium to hydrophobic antibiotics (novobiocin, fusidic acid, erythromycin, clindamycin, nafcillin, and cloxacillin). The polymyxin B nonapeptide-treated bacteria were as sensitive to these antibiotics as are deep rough mutants. A lysine polymer with 20 lysine residues (lysine 20) had a largely similar effect. Larger lysine polymers and the protamine salmine were bactericidal but, at sublethal concentrations, sensitized the strains to the antibiotics mentioned above, whereas lysine4, streptomycin, cytochrome c, lysozyme, and the polyamines cadaverine, spermidine, and spermine had neither bactericidal nor sensitizing activity.
Low-Cost Chipless Sensor Tags for Wearable User Interfaces (2019)

This paper addresses the design, the fabrication, and the experimental characterization of two fully-textile chipless tags used, for the first time, as wearable touch sensors. The first device is a multi-resonator chipless tag, wherein the information encoding relies on the presence/absence of resonance peaks. The second device consists of a hairpin resonator slotted on the ground plane and acting as a loading impedance of a microstrip line; in this case, the encoding mechanism is based on the variation of the resonance frequency. Prototypes for both devices were fabricated and characterized. Experimental tests performed on the prototypes exploiting two different measurement setups demonstrate that, when used as touch sensors, both the devices are able to encode four configurations corresponding to distinct relative positions between the sensor and the hand. The proposed devices are fully-textile solutions suitable for wearable applications in which low cost and a seamless integration with garments take priority over accuracy.
Passive Q switching of a diode-pumped Nd:YAG laser with a saturable absorber (1990)

A diode-pumped Nd:YAG laser is passively Q switched by using F(2)(-) color centers in lithium fluoride as a saturable absorber. When cw pumped with a laser diode, the laser produces pulses of 20-30-nsec duration at 1064 nm, with an energy of as much as 20 microJ and a peak power of more than 1 kW. Data are presented on pulse width, energy, and repetition rate as a function of pump power. When the laser is operated at high pulse energy levels, a gradual bleaching of the saturable absorber is observed.
Metasurface-Enhanced Raman Spectroscopy (mSERS) for Oriented Molecular Sensing (2022)

Surface-enhanced Raman spectroscopy (SERS) is a widely used sensing technique for ultrasensitivity chemical sensing, biomedical detection, and environmental analysis. Because SERS signal is proportional to the fourth power of the local electric field, several SERS applications have focused on the design of plasmonic nanogaps to take advantage of the extremely strong near-field enhancement that results from plasmonic coupling, but few designs have focused on how SERS detection is affected by molecular orientation within these nanogaps. Here, we demonstrate a nanoparticle-on-metal metasurface designed for near-perfect optical absorption as a platform for Raman detection of highly oriented molecular analytes, including two-dimensional materials and aromatic molecules. This metasurface platform overcomes challenges in nanoparticle aggregation, which commonly leads to low or fluctuating Raman signals in other colloidal nanoparticle platforms. Our metasurface-enhanced Raman spectroscopy (mSERS) platform is based on a colloidal Langmuir-Schaefer deposition, with up to 32% surface coverage density of nanogaps across an entire sensor chip. In this work, we perform both simulations of the local electric field and experimental characterization of the mSERS signal obtained for oriented molecular layers. We then demonstrate this mSERS platform for the quantitative detection of the drinking-water toxin polybrominated diphenyl ether (BDE-15), with a limit of detection of 0.25 μM under 530 μW excitation. This detection limit is comparable to other SERS-based sensors operating at laser powers over 3 orders of magnitude higher, indicating the promise of our mSERS platform for nondestructive and low-level analyte detection.
Corrigendum: Interactions of Bacteriophages and Bacteria at the Airway Mucosa: New Insights Into the Pathophysiology of Asthma (2022)

[This corrects the article DOI: 10.3389/falgy.2020.617240.].
The Catalytic Effect of Fluoroalcohol Mixtures Depends on Domain Formation (2017)

In the present contribution, we investigated catalytically active mixtures of 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) and aqueous H2O2 by molecular dynamics simulations. It is clearly observable that the HFIP molecule strongly binds to the H2O2, which is necessary for the desired catalytic reaction to occur. Upon the addition of the substrate cyclooctene to the solution, this interaction is enhanced, which suggests that the catalytic activity is increased by the presence of the hydrocarbon. We could clearly observe the microheterogeneous structure of the mixture, which is the result of the separation of the hydroxyl groups, water, and H2O2 from the fluorinated alkyl moiety in the form of large domains, which span through large areas of the system. The hydrocarbon, however, does not fit into either one of these two microphases, and it forms separate aggregates in the macroscopically homogeneous liquid, creating thereby a triphilic mixture. The latter kinds of aggregates are mostly surrounded by the fluorous moieties, and therefore, the H2O2 has to move from the polar through the fluorous domain to be able to react with the cyclooctene. Accordingly, the present reaction should be described figuratively as a phase transfer or an interfacial reaction, rather than a homogeneous liquid-phase process.
Effects of chlorhexidine gel on periodontal health of abutment teeth in patients with overdentures (1991)

The aim of this study was to test the effect of chlorhexidine gel application on periodontal health of abutment teeth in patients with overdentures. 19 patients with immediate overdentures were distributed at random among 2 experimental groups. In these groups, a placebo and chlohexidine gel were daily applied. Patients were recalled at 6-month intervals over a period of 2 years. In both groups, pocket depth, tooth mobility and bleeding index were initially found to decrease after insertion of the overdenture. In the chlorhexidine group, the bleeding index remained very low over the 2-year period. Whereas in the placebo group, the bleeding index gradually returned to the baseline values. The pocket depth in the chlorhexidine group remained below the baseline value, in contrast to values in the control group. The width of the attached gingiva decreased in both the groups, but less in the chlorhexidine group.
Improved measurement of the dynamic loads acting on rotating parachutes (1992)

An experimental apparatus for measuring the steady and nonsteady aerodynamic loads acting on parachutes and decelerators has been designed and built in the Wind Tunnel Laboratory at Technion. This apparatus was installed in the subsonic wind tunnel. Calibration tests were carried out with both deadweights and a rigid body simulating the flow around a rotating parachute. Good agreement was obtained between the results of these tests and previously recorded data. The experiments with parachutes included both static and rotating cases of a cross-type parachute with a W/L of 0.333. The measurements in the static case included all six force and moment components. In the rotating case, five load components were measured plus roll damping and roll transfer capability. The results prove the ability of the modified system in accurately measuring the aerodynamic loads without interrupting the flowfield of the parachute, as well as the versatility of the apparatus in obtaining dynamic data previously unobtainable in wind-tunnel measurements.
Security of computer communication (1978)

Cryptographic algorithms and systems can provide high levels of security whencomputers are connected in a distributed processing network.
Reinnervation of Vastus lateralis is increased significantly in seniors (70-years old) with a lifelong history of high-level exercise (2013, revisited here in 2022) (2022)

In 2013 we presented results showing that at the histological level lifelong increased physical activity promotes reinnervation of muscle fibers in aging muscles. Indeed, in muscle biopsies from 70-year old men with a lifelong history of high-level physical activity, we observed a considerable increase in fiber-type groupings (F-TG), almost exclusively of the slow type. Slow-type transformation by denervation-reinnervation in senior sportsmen seems to fluctuate from those with scarce fiber-type transformation and groupings to almost fully transformed muscle, going through a process in which isolated fibers co-expressing fast and slow Myosin Heavy Chains (MHCs) seems to fill the gaps. Taken together, our results suggest that, beyond the direct effects of aging on the muscle fibers, changes occurring in skeletal muscle tissue appear to be largely, although not solely, a result of sparse denervation-reinnervation. The lifelong exercise allows the body to adapt to the consequences of the age-related denervation and to preserve muscle structure and function by saving otherwise lost muscle fibers through recruitment to different, mainly slow, motor units. These beneficial effects of high-level life-long exercise on motoneurons, specifically on the slow type motoneurones that are those with higher daily activity, and on muscle fibers, serve to maintain size, structure and function of muscles, delaying the functional decline and loss of independence that are commonly seen in late aging. Several studies of independent reserchers with independent analyses confirmed and cited our 2013 results. Thus, the results we presented in our paper in 2013 seem to have held up rather well.
Medical resource utilization and costs for intraoperative and early postoperative periprosthetic hip fractures following total hip arthroplasty in the medicare population (2019)

This study assessed the impact of intraoperative and early postoperative periprosthetic hip fractures (PPHFx) after primary total hip arthroplasty (THA) on health care resource utilization and costs in the Medicare population.This retrospective observational cohort study used health care claims from the United States Centers for Medicare and Medicaid Standard Analytic File (100%) sample. Patients aged 65+ with primary THA between 2010 and 2016 were identified and divided into 3 groups - patients with intraoperative PPHFx, patients with postoperative PPHFx within 90 days of THA, and patients without PPHFx. A multi-level matching technique, using direct and propensity score matching was used. The proportion of patients admitted at least once to skilled nursing facility (SNF), inpatient rehabilitation facility (IRF), and readmission during the 0 to 90 or 0 to 365 day period after THA as well as the total all-cause payments during those periods were compared between patients in PPHFx groups and patients without PPHFx.After dual matching, a total 4460 patients for intraoperative and 2658 patients for postoperative PPHFx analyses were included. Utilization of any 90-day post-acute services was statistically significantly higher among patients in both PPHFx groups versus those without PPHFx: for intraoperative analysis, SNF (41.7% vs 30.8%), IRF (17.7% vs 10.1%), and readmissions (17.6% vs 11.5%); for postoperative analysis, SNF (64.5% vs 28.7%), IRF (22.6% vs 7.2%), and readmissions (92.8% vs 8.8%) (all P < .0001). The mean 90-day total all-cause payments were significantly higher in both intraoperative ($30,114 vs $21,229) and postoperative ($53,669 vs $ 19,817, P < .0001) PPHFx groups versus those without PPHFx. All trends were similar in the 365-day follow up.Patients with intraoperative and early postoperative PPHFx had statistically significantly higher resource utilization and payments than patients without PPHFx after primary THA. The differences observed during the 90-day follow up were continued over the 1-year period as well.
Dynamics of pelagic mucilage produced by the invasive, cyclotelloid diatom, Lindavia intermedia, in oligotrophic lakes of New Zealand (2022)

Marine pelagic mucilages (e.g., marine snow) have been reported to a greater extent than their lacustrine counterparts. A pelagic mucilage primarily comprised of chitin secretions from the invasive centric diatom, Lindavia intermedia , has been reported since the early 2000s, primarily from large, oligotrophic pre-alpine lakes of the South Island of New Zealand. To better understand the factors related to mucilage abundance, we monitored its abundance as well as factors potentially related to mucilage production over time in four mucilage-afflicted lakes. Temporal mucilage dynamics were episodic, with peaks in abundance occurring during any season, but most often during summer and autumn. Chitin was confirmed to be an important component of the mucilage, but the chitin content varied between 1 and 12% of the mucilage dry mass in the lakes. An RT-qPCR assay for chitin synthase gene overexpression in L . intermedia showed that overexpression occurred in summer and autumn, often when peaks in mucilage abundance also occurred. A correlation between mucilage and phytoplankton abundance was only observed in one of the lakes. Both dissolved reactive and total phosphorus concentrations were often below analytical detection limits in these lakes. Nitrate concentrations were also low and showed negative correlations with mucilage abundance. This suggests either that the secrection of chitinous mucilage by L . intermedia significantly depleted the available N in the water column or that mucilage facilitated N uptake by L . intermedia and/or other microorganisms associated with the mucilage. Pelagic mucilage in New Zealand lakes shares many characteristics of other conspicuous mucilage phenomena, including lake snow and marine snow. While our correlational analyses revealed some relationships and associations with mucilage abundance, the strengths of these were quite variable, indicating that as yet unstudied mucilage loss processes in these lakes (e.g., sedimentation, disintegration, decomposition, assimilation) likely also play important roles in regulating mucilage abundance.
Use of oxygen gas in diamond film growth for improving stress and crystallinity properties of an x-ray mask (1998)

In order to improve the properties, such as stress and crystallinity, of diamond films for use as x-ray masks, we have studied the effectiveness of the addition of O2 to a CH4/H2 gaseous mixture in magnetically enhanced microwave plasma chemical vapor deposition. As the O2 concentration was increased, diamond grain growth became more dominant over the nondiamond component and grain growth continued. As a result, stress shifted toward the tensile regime. We explain the mechanism of this diamond stress shift by using the stress generation model proposed by Chaudhari. Under the optimum deposition conditions, i.e., CH4/O2/H2=2.0/0.5/97.5 vol % at 920 °C, we obtained (111)-textured polycrystalline diamond, which had high crystallinity and improved stress properties. The average stress was 147 MPa (tensile) and the uniformity was less than or equal to +21.1%; −12.2% was achieved within a 50-mm-diam area for a 2.3-μm-thick film. The biaxial Young’s modulus was evaluated by the bulge test, and was found to be 1000±51 GPa. This diamond membrane caused little in-plane distortion-induced backetching, i.e., max (x,y)=(27,31) nm, due to its high biaxial Young’s modulus.