gebhart/patrepeval huggingface dataset:
Plasmon Resonances of a Gold Nanostar (2007)

Using the finite-difference time-domain method, we show that the plasmons of a nanostar result from hybridization of plasmons of the core and tips of the nanoparticle. The nanostar core serves as a nanoscale antenna, dramatically increasing the excitation cross section and the electromagnetic field enhancements of the tip plasmons. Our analysis demonstrates that the plasmon hybridization picture can be combined with numerical approaches to interpret the physical origin of the plasmons of highly complex nanostructures.
Therapeutic Targeting of Protein Disulfide Isomerase PDIA1 in Multiple Myeloma (2021)

Multiple myeloma is a genetically complex hematologic neoplasia in which malignant plasma cells constantly operate at the maximum limit of their unfolded protein response (UPR) due to a high secretory burden of immunoglobulins and cytokines. The endoplasmic reticulum (ER) resident protein disulfide isomerase, PDIA1 is indispensable for maintaining structural integrity of cysteine-rich antibodies and cytokines that require accurate intramolecular disulfide bond arrangement. PDIA1 expression analysis from RNA-seq of multiple myeloma patients demonstrated an inverse relationship with survival in relapsed or refractory disease, supporting its critical role in myeloma persistence. Using a structure-guided medicinal chemistry approach, we developed a potent, orally bioavailable small molecule PDIA1 inhibitor CCF642-34. The inhibition of PDIA1 overwhelms the UPR in myeloma cells, resulting in their apoptotic cell death at doses that do not affect the normal CD34<sup>+</sup> hematopoietic stem and progenitor cells. Bortezomib resistance leads to increased PDIA1 expression and thus CCF642-34 sensitivity, suggesting that proteasome inhibitor resistance leads to PDIA1 dependence for proteostasis and survival. CCF642-34 induces acute unresolvable UPR in myeloma cells, and oral treatment increased survival of mice in the syngeneic 5TGM1 model of myeloma. Results support development of CCF642-34 to selectively target the plasma cell program and overcome the treatment-refractory state in myeloma.
Efficiently mining frequent trees in a forest: algorithms and applications (2005)

Mining frequent trees is very useful in domains like bioinformatics, Web mining, mining semistructured data, etc. We formulate the problem of mining (embedded) subtrees in a forest of rooted, labeled, and ordered trees. We present TREEMINER, a novel algorithm to discover all frequent subtrees in a forest, using a new data structure called scope-list. We contrast TREEMINER with a pattern matching tree mining algorithm (PATTERNMATCHER), and we also compare it with TREEMINERD, which counts only distinct occurrences of a pattern. We conduct detailed experiments to test the performance and scalability of these methods. We also use tree mining to analyze RNA structure and phylogenetics data sets from bioinformatics domain.
ChemInform Abstract: Synthesis of Glycopeptide Conjugates via Ring‐Opening Polymerization of Sugar‐Substituted α‐Amino Acid N‐Carboxyanhydrides (GlycoNCAs) (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A simple automated method for continuous fieldwise measurement of microvascular hemodynamics (2019)

Microvascular perfusion dynamics are vital to physiological function and are frequently dysregulated in injury and disease. Typically studies measure microvascular flow in a few selected vascular segments over limited time, failing to capture spatial and temporal variability. To quantify microvascular flow in a more complete and unbiased way we developed STAFF (Spatial Temporal Analysis of Fieldwise Flow), a macro for FIJI open-source image analysis software. Using high-speed microvascular flow movies, STAFF generates kymographs for every time interval for every vascular segment, calculates flow velocities from red blood cell shadow angles, and outputs the data as color-coded velocity map movies and spreadsheets. In untreated mice, analyses demonstrated profound variation even between adjacent sinusoids over seconds. In acetaminophen-treated mice we detected flow reduction localized to pericentral regions. STAFF is a powerful new tool capable of providing novel insights by enabling measurement of the complex spatiotemporal dynamics of microvascular flow.
Application of Problem-Based Learning in an Engineering Course* (2003)

The usual way of learning technical knowledge about a microcontroller (MCU) is by reading relevant handbooks and textbooks. This method requires students to memorize many technical terms and usually ignores its actual application of the data. In this paper, a new approach is proposed using the problem-based learning technique to convey such engineering knowledge. A creative group project was designed for the class whereby students were required to develop their own way of designing a calculator using MCU. Throughout the project, they acquired self-learning techniques to tackle new problems. Moreover, problem-based learning provided students with a cooperative learning environment to enhance their learning capabilities.
Unity IDF correction for AC to DC converter based on modulation strategy (2002)

Modulation strategy for a matrix structured ac to dc converter is developed. This modulation strategy enables the input displacement factor correction without current sensing. Mathematical proof that the ac to dc converter can operate with unity input displacement factor is provided by analysis based on the switching matrix approach. Theoretical analysis demonstrates the algorithm requirements. Computer simulation and experimental results supporting this ability are reported.
Role of cellular interactions in axonal growth and regeneration (1995)

Abstract This chapter considers how growth cone motility and changes in the neuronal cytoskeleton are modulated by cues from the local environment. It begins by examining the mechanisms by which positive and negative environmental cues guide growing axons. It then discusses the various intrinsic and extrinsic factors that can modulate changes in axonal caliber. Finally, the chapter examines the critical role of axonal environments in neuronal survival and axonal regeneration after injury.
Novel Meander Line Slow Wave Structure for W-band TWT (2020)

The unfeasible fabrication of helix slow wave structures in W-band traveling wave tubes makes necessary to find alternative slow wave structures in order to amplify the RF signal to the output levels required to overcome atmospheric attenuation in satellite communications. Meander lines are nowadays being studied as slow wave structures for W-band traveling wave tubes due to their favorable properties compared to full metal alternatives. A novel meander line topology is introduced in this work, showing that high gain and output power can be achieved using a low-voltage electron beam. Cold and large signal simulations are presented in this work.
GENOTYPE AND DRUG RESISTANCE OF CLINICAL AND ENVIRONMENTAL VIBRIO CHOLERAE NON-O1/NON-O139 IN NORTHEASTERN THAILAND. (2014)

A total of 124 V cholerae non-O1/non-O139 isolates were collected in Khon Kaen, Thailand from diarrheal patients, asymptomatic carriers and environmental water. The presence of virulence-associated and regulatory genes including ctxA, tcpA, zot, ace, ompU, stn, hlyA and toxR) were examined using multiplex PCR. The genomic diversity of the various V. cholerae isolates were differentiated using the random amplified polymorphic DNA (RAPD) method. Antimicrobial susceptibility was tested using disk diffusion. All of V. cholerae non-O/non-O139 isolates carried hlyA and toxR and none carried ctxA and tcpA. The zot, ace and both genes together were found in 1.6%, 4.7% and 4.7% of 64 clinical V. cholerae non-O1 isolates, respectively, while the environmental ones did not. The stn gene was found in 3.1% (2/64) of the clinical and 3.3% (2/60) of the environmental isolates. The RAPD patterns were differentiated into 45 types (A to 2S). RAPD type A (32.3%) was the most frequently found in both clinical and environmental V cholerae non-O1 strains (34.4% and 30.0%, respectively); indicating that there was a clonal relationship between some clinical and environmental isolates whereas almost all of the environmental isolates belonged to different clones. All strains were sensitive to ciprofloxacin and norfloxacin. The environmental isolates (30%) were more resistant than the clinical ones (21.9%). Resistance to sulfamethoxazole/trimethoprim and tetracycline among the clinical isolates occurred in 9.4% (6/64) in 2007, during which period the prevalence of V cholerae O1 increased. We conclude that V. cholerae non-O1/non-O139 from the aquatic environment are potentially pathogenic and this same aquatic environment may be a source of antimicrobial resistance in V. cholerae.
An improved battery charger/discharger topology with power factor correction (2002)

Distributed power systems are an attractive solution to meet the requirements (redundancy, modularity, battery backup, etc.) for the next generation of power supply systems. In addition, the normalization regarding power factor and total harmonic distortion makes it necessary to include power factor correction in the input stage in those architectures. This paper presents a novel approach of an integrated battery charger/discharger which offers power factor correction and battery galvanic isolation in a simple structure Placing the battery into the primary side overcomes the need of galvanic isolation integration in each one of the DC/DC on-board converters when this topology is used as part of a distributed power supply system.
4 Exploiting Temporal Properties (2020)

This dissertation deals with the problem of capturing human motions and poses using a single camera. The frst part of the thesis proposes two closely related approaches for the 3D reconstruction of human motions from image sequences. To resolve inherent ambiguities in monocular 3D reconstruction the main idea of this part is to exploit temporal properties of human motions in combination with a human body model learned from training data. The second part of the thesis tackles the problem of reconstructing a human pose from a single image. A human body model is learned by training a deep neural network that covers nonlinearities and anthropometric constraints.
Psychotropic Drugs and Outcome in Patients Receiving Anticoagulant Therapy for Venous Thromboembolism (2020)

During the course anticoagulation for VTE, patients using psychotropics at baseline were at increased risk for intracranial bleeding.
Blockwise processing applied to brain microvascular network study (2006)

The study of cerebral microvascular networks requires high-resolution images. However, to obtain statistically relevant results, a large area of the brain (several square millimeters) must be analyzed. This leads us to consider huge images, too large to be loaded and processed at once in the memory of a standard computer. To consider a large area, a compact representation of the vessels is required. The medial axis is the preferred tool for this application. To extract it, a dedicated skeletonization algorithm is proposed. Numerous approaches already exist which focus on computational efficiency. However, they all implicitly assume that the image can be completely processed in the computer memory, which is not realistic with the large images considered here. We present in this paper a skeletonization algorithm that processes data locally (in subimages) while preserving global properties (i.e., homotopy). We then show some results obtained on a mosaic of three-dimensional images acquired by confocal microscopy.
Toward Tertiary Amine-Modulated Acid-Triggered Hydrolysis of Copolymers Containing Pendent Ortho Ester Groups (2013)

We describe an efficient approach to modulate the hydrolysis of the ortho ester-containing polymers by incorporating different amount of tertiary amino (TA) groups. The block copolymers (NE0–NE3) contain a hydrophilic poly(ethylene glycol) (PEG) segment and hydrophobic chains constituted by random methacrylate copolymers with pendent acid-labile cyclic ortho ester and TA groups and were synthesized by a two-step approach. First, atom transfer radical copolymerization of 2-hydroxyethyl methacrylate and 2-(diethylamino)ethyl methacrylate using mPEG45-Br as a macroinitiator afforded the block copolymer precursors. Then, reaction of the precursors with 2-ethylidene-4-methyl-1,3-dioxolane transformed the pendent hydroxyl groups into cyclic ortho ester groups. The hydrophobic chains are similar in degree of polymerization, but the percent molar content of TA increases from 0% for NE0 to ∼15% for NE3. In phosphate buffer at pH 8.4, all the four amphiphilic block copolymers can self-assemble into stable nanoparticles with a monomodal distribution, which have a similar hydrophilic/hydrophobic balance as revealed by using pyrene and Nile red (NR) as fluorescent probes. Kinetic measurements of the ortho ester hydrolysis in the copolymer nanoparticles were studied at different pH values by 1H NMR spectroscopy, NR fluorescence probe, and light scattering. The results indicated that all the copolymer nanoparticles exhibit the pH-dependent hydrolysis behaviors with the half-life times ranging from hundreds of minutes at pH 5.4 to several days at neutral pH. More importantly, we found that the TA units have an amphoteric effect on the hydrolysis kinetics of the surrounding pendent ortho esters in acidic media. When compared with copolymer nanoparticles of NE0 with no TA unit, the NE1 nanoparticles with a small amount of TA unit hydrolyzed much slower, whereas a faster hydrolysis was observed for the NE3 nanoparticles containing a higher amount of TA unit.
Distribution of the Estimators for Autoregressive Time Series with a Unit Root (1979)

Abstract Let n observations Y 1, Y 2, ···, Y n be generated by the model Y t = pY t−1 + e t , where Y 0 is a fixed constant and {e t } t-1 n is a sequence of independent normal random variables with mean 0 and variance σ2. Properties of the regression estimator of p are obtained under the assumption that p = ±1. Representations for the limit distributions of the estimator of p and of the regression t test are derived. The estimator of p and the regression t test furnish methods of testing the hypothesis that p = 1.
Optically Controlled Opening of Self-Sealing Giant Unilamellar Vesicles (2012)

Micron-scale giant unilamellar vesicles could be readily opened using a focused laser beam in situ. These giant unilamellar vesicles have potential use as versatile microreactors possessing temporally and spatially controlled optical opening.
A Pump-Gate Jot Device With High Conversion Gain for a Quanta Image Sensor (2015)

A new photodetector designed for Quanta image sensor application is proposed. The photodetector is a backside-illuminated, buried photodiode with a vertically integrated pump and transfer gate and a distal floating diffusion to reduce parasitic capacitance. The structure features compact layout and high conversion gain. The proposed device is modeled and simulated, and its performance characteristics estimated.
Phase transition of an unnatural analog of phosphatidylcholine: Phosphatidyl‐N‐isopropylethanolamine (1981)

The phase-transition temperature, of an aqueous dispersion of dipalmitoyl phosphatidyl-N-isopropylethanolamine was determined was determined usingtrans-parinaric acid as a fluorescent probe. Phosphatidyl-N-isopropylethanolamine has a phase-transition temperature that is 3-4 C higher than the corresponding natural analog of dipalmitoyl phosphatidylcholine.
Growth of InP directly on Si by corrugated epitaxial lateral overgrowth (2015)

In an attempt to achieve an InP–Si heterointerface, a new and generic method, the corrugated epitaxial lateral overgrowth (CELOG) technique in a hydride vapor phase epitaxy reactor, was studied. An InP seed layer on Si (0 0 1) was patterned into closely spaced etched mesa stripes, revealing the Si surface in between them. The surface with the mesa stripes resembles a corrugated surface. The top and sidewalls of the mesa stripes were then covered by a SiO2 mask after which the line openings on top of the mesa stripes were patterned. Growth of InP was performed on this corrugated surface. It is shown that growth of InP emerges selectively from the openings and not on the exposed silicon surface, but gradually spreads laterally to create a direct interface with the silicon, hence the name CELOG. We study the growth behavior using growth parameters. The lateral growth is bounded by high index boundary planes of {3 3 1} and {2 1 1}. The atomic arrangement of these planes, crystallographic orientation dependent dopant incorporation and gas phase supersaturation are shown to affect the extent of lateral growth. A lateral to vertical growth rate ratio as large as 3.6 is achieved. X-ray diffraction studies confirm substantial crystalline quality improvement of the CELOG InP compared to the InP seed layer. Transmission electron microscopy studies reveal the formation of a direct InP–Si heterointerface by CELOG without threading dislocations. While CELOG is shown to avoid dislocations that could arise due to the large lattice mismatch (8%) between InP and Si, staking faults could be seen in the layer. These are probably created by the surface roughness of the Si surface or SiO2 mask which in turn would have been a consequence of the initial process treatments. The direct InP–Si heterointerface can find applications in high efficiency and cost-effective Si based III–V semiconductor multijunction solar cells and optoelectronics integration.
Sesquiterpene Lactones and Acetogenin Lactones from the Hepaticae and Chemosystematics of the Liverworts Frullania, Plagiochila and Porella (2001)

Liverworts (Hepaticae) contain various sesquiterpene lactones and acetogenin lactones which show occasionally interesting biological activity and are of very valuable for the chemosystematic study of liverworts.The distribution of the sesquiterpene lactones and acetogenin lactones in liverworts and their biological activity and chemosystematics of the Frullania, Plagochila and Porella are reviewed.
Confident estimation for multistage measurement sampling and aggregation (2008)

Measurement, collection, and interpretation of network usage data commonly involves multiple stage of sampling and aggregation. Examples include sampling packets, aggregating them into flow statistics at a router, sampling and aggregation of usage records in a network data repository for reporting, query and archiving. Although unbiased estimates of packet, bytes and flows usage can be formed for each sampling operation, for many applications it is crucial to know the inherent estimation error. Previous work in this area has been limited mainly to analyzing the estimator variance for particular methods, e.g., independent packet sampling. However, the variance is of limited use for more general sampling methods, where the estimate may not be well approximated by a Gaussian distribution.
Novel Metal-Organic Frameworks for Efficient Stationary Sources via Oxyfuel Combustion (2015)

Oxy-fuel combustion is a well-known approach to improve the heat transfer associated with stationary energy processes. Its overall penetration into industrial and power markets is constrained by the high cost of existing air separation technologies for generating oxygen. Cryogenic air separation is the most widely used technology for generating oxygen but is complex and expensive. Pressure swing adsorption is a competing technology that uses activated carbon, zeolites and polymer membranes for gas separations. However, it is expensive and limited to moderate purity O₂ . MOFs are cutting edge materials for gas separations at ambient pressure and room temperature, potentially revolutionizing the PSA process and providing dramatic process efficiency improvements through oxy-fuel combustion. This LDRD combined (1) MOF synthesis, (2) gas sorption testing, (3) MD simulations and crystallography of gas siting in pores for structure-property relationship, (4) combustion testing and (5) technoeconomic analysis to aid in real-world implementation.
Reaction‐induced phase separation in poly(vinyl acetate)/polyester blend (2006)

Abstract In blends of unsaturated polyester (UP), poly (vinyl acetate) (PVAc), and styrene, a reaction‐induced phase separation occurs upon curing that is due to the crosslinking between styrene and the UP molecules. The evolution of the morphology was observed by optical microscopy on a heated stage. Light transmission was used in parallel to precisely detect the onset of phase separation and the formation of microvoids. Using Fourier transform IR spectroscopy in the same conditions, the conversions at phase separation and at microvoiding were evaluated. Phase separation occurs at a very low degree of conversion and microvoiding develops at around 60% of conversion. The final morphology of the blend was investigated by scanning electron microscopy. The relative influences of the cure temperature, the concentration in PVAc, and the molecular weight of PVAc were investigated. It was confirmed that the early stages of the reaction at high temperature determine the final morphology of the blends. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 102: 3877–3888, 2006
News (1984)

IEEE Signs Agreement with NUTN Network of 110 Higher Education Institutions Distributing Live Satellite Broadcasts of the Institute's Education Courses
Gas and Solid Mixing in Fluidized Beds (1949)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGas and Solid Mixing in Fluidized BedsE. R. Gilliland and E. A. MasonCite this: Ind. Eng. Chem. 1949, 41, 6, 1191–1196Publication Date (Print):June 1, 1949Publication History Published online1 May 2002Published inissue 1 June 1949https://pubs.acs.org/doi/10.1021/ie50474a013https://doi.org/10.1021/ie50474a013research-articleACS PublicationsRequest reuse permissionsArticle Views385Altmetric-Citations75LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Development and application of metagenomic tools for studying ecosystem potentials. (2013)

info:eu-repo/semantics/published
Cinderella’s Lessons on Footbinding: How Tiny Feet Found their Way into the Chinese Cinderella Story (2013)

Shoes, slippers, feet and sandals play one of the most pivotal roles in the prominent Cinderella stories through the tale’s history. Tracing versions of the tale geographically as it spread throughout Central Asia and then throughout the globe can exemplify the different traditions and mores a society entrusts to the story. However, feet and their coverings survive all of these retellings after a certain point. Footbinding and the spread of early versions of the Cinderella tale share the same time periods in the ninth-century, and the tradition of footbinding makes a lasting impact on the story once it begins moving from southern China.