gebhart/patrepeval huggingface dataset:
ChemInform Abstract: OEFFNUNG VON AZIRIDINEN IN SAUREM MILIEU, POTENTIELLE AZOMETHIN‐YLIDE, BEWEISE FUER IMMONIUM‐SALZE. UNTERSUCHUNG IHRER REAKTIVITAET (1973)

Abstract Aus den beiden Aziridinen (Ia) und (Ib) oder aus dem Oxazolin (III) entstehen die Azomethin‐Ylide (IIa)‐(Ilc), deren weitere Reaktionen untersucht werden.
ChemInform Abstract: Application of the Study of Reactivity of Alkaline Salts of Isocyanuric Acid to the Synthesis of Mono‐ and Trisubstituted Isocyanurates. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Carbon dioxide adsorption performance of N-doped zeolite Y templated carbons (2011)

N-Doped microporous carbons are prepared using zeolite NaY as a hard template with furfuryl alcohol/acetonitrile as carbon precursors. CO2 adsorption performances of these carbons are investigated intensively. Structure analysis shows that the replication of zeolite regularity, pore texture and the type of nitrogen functionalities strongly depends on the carbonization temperature. Basic nitrogen functionalities can be efficiently introduced into the carbon framework, which significantly facilitate CO2 uptake via chemical adsorption. The CO2 adsorption isotherms correlated with the Dubinin–Astakhov models, and the isosteric heats of adsorption are calculated using the Clausius–Clapeyron equation. The maximum CO2 adsorption capacity of 10.4 wt% is obtained for the YTC7 carbon due to its high surface area and abundant nitrogen functionalities. CO2 chemical adsorption on the carbons decreases with carbonization temperature due to the decomposition of basic nitrogen functionalities at higher temperature. High CO2 adsorption capacities of up to 9.3 wt% at 25 °C and 4.1 wt% at 70 °C are obtained for the YTC6 carbon. The present study suggests that low temperature vapor deposition of acetonitrile is a promising alternative method of toxic ammonia treatment for CO2 adsorption.
Lower Temperature, Lower Cost Molten Sodium Batteries. (2021)

Abstract not provided.
Investigating the catalytic mechanism of the meta-cleavage product hydrolases (2013)

The meta-cleavage product (MCP) hydrolases are members of the α/β-hydrolase superfamily that utilize a Ser-His-Asp triad to catalyze the hydrolysis of a C-C bond. The catalytic mechanism of the MCP hydrolases is poorly defined and particularly interesting due to a requisite substrate ketonization that precedes hydrolysis. To resolve the catalytic mechanism of the MCP hydrolases, two enzymes were studied: tetrameric BphDLB400 from Burkholderia xenovorans LB400 and dimeric DxnB2 from Sphingomonas witichii RW1. Both efficiently hydrolyze 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid (HOPDA) to produce 2-hydroxypenta-2,4-dienoic acid (HPD) and benzoic acid. A series of experiments established that BphDLB400 uses an histidine-independent nucleophilic mechanism of catalysis and is half-site reactive. Benzoylation of Ser112 was demonstrated by LC ESI/MS/MS analyses and a pre-steady-state kinetic burst of HPD formation indicated the reactivity. While acylation during HOPDA hydrolysis by BphDLB400 occurred on a similar timescale for the WT and H265Q variant, esterase activity was abrogated in the histidine variant. Thus, alternative mechanisms of nucleophile activation are employed for C-C and C-O bond cleavage. A covalent mechanism of catalysis was inferred for DxnB2, however, the turnover of HOPDA was 1:1 with respect to enzyme concentration. A solvent kinetic isotope effect suggested that a proton transfer, and therefore, substrate ketonization determines the rate of acylation in the MCP hydrolases. Substrate ketonization, and therefore acylation, can be indirectly observed as consumption of ESred, an intermediate named for its bathochromically-shifted absorption spectrum. A proton transfer to ESred allowed the assignment of this species to an enzyme-bound HOPDA dianion. An extended Brønsted analysis revealed a linear correlation between substrate basicity and the rate constant determined for the ketonization reaction. Finally, the MCP hydrolase P-subsite, which contacts the MCP dienoate moiety, was definitively linked to substrate ketonization. In DxnB2 Asn43 and Arg180 variants, ESred formation was found to limit this proton transfer reaction. A substrate-assisted nucleophilic mechanism of catalysis has been proposed for the MCP hydrolases. Therein, the electron-rich dienoate moiety substitutes for the His-Asp pair as the general base for nucleophile activation. Overall, definition of the chemical mechanism of the MCP hydrolases has implications for environmental bioremediation strategies and the rational design of therapeutics.
An examination of the determinants of low muscle mass and low muscle strength in older adults in Ireland (2017)

An abstract is not available for this content. As you have access to this content, full HTML content is provided on this page. A PDF of this content is also available in through the ‘Save PDF’ action button.
Distribution of immunoglobulins and secretory component in gastric cancer of the aged (1990)

The secretory immune system plays an important role in the local humoral immunity of the gastrointestinal tract. In order to evaluate humoral immunity in gastric cancer, distribution of immunoglobulins (Ig) and secretory component was immunohistochemically studied in 74 early and 15 advanced primary gastric cancers. In non-cancerous gastric mucosa, IgA and IgM, and secretory component were mainly identified in the cytoplasm of the intestinal metaplasia. In early gastric cancer of well-differentiated type, the localization of IgA and IgM, and secretory component was similar to that of intestinal metaplasia. In advanced gastric cancer, they were faintly observed and showed low positivity. The number of Ig-containing cells infiltrating cancerous stroma was enumerated. Immunoglobulin A-containing cells were dominant in the stroma of early gastric cancer. On the other hand, there were few Ig-containing cells in the stroma of advanced gastric cancer, and the number of IgA-containing and IgM-containing cells was also decreased. These results suggest that local humoral immunity is suppressed in gastric cancer, especially in advanced gastric cancer.
History and highlights of the teratological collection in theNarrenturm, Vienna (Austria) (2023)

The collection of the Narrenturm in Vienna houses and maintains more than 50,000 objects including approximately 1200 teratological specimens; making it one of the biggest collections of specimens from human origin in Europe. The existence of this magnificent collection-representing an important resource for dysmorphology research, mostly awaiting contemporary diagnoses-is not widely known in the scientific community. Here, we show that the Narrenturm harbors a wealth of specimens with (exceptionally) rare congenital anomalies. These museums can be seen as physical repositories of human malformation, covering hundreds of years of dedicated collecting and preserving, thereby creating unique settings that can be used to expand our knowledge of developmental conditions that have to be preserved for future generations of scientists.
Assessment of Global Health Competence of Nursing Faculty in Prelicensure Programs (2021)

Nursing faculty participants identified several areas for improvement in their knowledge of global health issues. [J Nurs Educ. 2021;60(1):20-24.].
A Lettuce (Lactuca sativa) Homolog of Human Nogo-B Receptor Interacts with cis-Prenyltransferase and Is Necessary for Natural Rubber Biosynthesis (2014)

Natural rubber (cis-1,4-polyisoprene) is an indispensable biopolymer used to manufacture diverse consumer products. Although a major source of natural rubber is the rubber tree (Hevea brasiliensis), lettuce (Lactuca sativa) is also known to synthesize natural rubber. Here, we report that an unusual cis-prenyltransferase-like 2 (CPTL2) that lacks the conserved motifs of conventional cis-prenyltransferase is required for natural rubber biosynthesis in lettuce. CPTL2, identified from the lettuce rubber particle proteome, displays homology to a human NogoB receptor and is predominantly expressed in latex. Multiple transgenic lettuces expressing CPTL2-RNAi constructs showed that a decrease of CPTL2 transcripts (3-15% CPTL2 expression relative to controls) coincided with the reduction of natural rubber as low as 5%. We also identified a conventional cis-prenyltransferase 3 (CPT3), exclusively expressed in latex. In subcellular localization studies using fluorescent proteins, cytosolic CPT3 was relocalized to endoplasmic reticulum by co-occurrence of CPTL2 in tobacco and yeast at the log phase. Furthermore, yeast two-hybrid data showed that CPTL2 and CPT3 interact. Yeast microsomes containing CPTL2/CPT3 showed enhanced synthesis of short cis-polyisoprenes, but natural rubber could not be synthesized in vitro. Intriguingly, a homologous pair CPTL1/CPT1, which displays ubiquitous expressions in lettuce, showed a potent dolichol biosynthetic activity in vitro. Taken together, our data suggest that CPTL2 is a scaffolding protein that tethers CPT3 on endoplasmic reticulum and is necessary for natural rubber biosynthesis in planta, but yeast-expressed CPTL2 and CPT3 alone could not synthesize high molecular weight natural rubber in vitro.
Zero-voltage-switching realized by magnetizing current of transformer in push-pull DC-DC converter (2002)

The authors present a novel type of zero-voltage-switched (ZVS) push-pull DC-DC power converter with two synchronous rectifiers in the secondary circuit. ZVS is realized using the magnetizing current of the transform as a current source during the commutation. The output voltage is controlled by pulsewidth modulation (PWM) with a constant switching frequency. The circuit operation is described using equivalent circuits. The steady-state and dynamic characteristics are analyzed. The characteristics were confirmed experimentally.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Factor XIIIa-dependent retention of red blood cells in clots is mediated by fibrin -chain crosslinking Running Title: Fibrin crosslinking promotes clot RBC retention (2017)

Department of Pathology and Laboratory Medicine and McAllister Heart Institute, University of North Carolina at Chapel Hill, Chapel Hill, United States Division of Cardiovascular and Diabetes Research, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom Canadian Blood Services, and Department of Laboratory Medicine and Pathobiology, St. Michael's Hospital, University of Toronto, Toronto, Canada Department of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, United States Wallace C. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, United States Aflac Cancer and Blood Disorders Center, Department of Pediatrics, Emory University School of Medicine, Atlanta, United States Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, United States Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, United States Research Institute, Bloodworks Northwest, Seattle, United States Department of Medicine, University of Washington, Seattle, United States Department of Experimental Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands Department of Plasma Proteins, Sanquin Research, Amsterdam, Netherlands
Safety and Effectiveness of Rasagiline in Chinese Patients with Parkinson’s Disease: A Prospective, Multicenter, Non-interventional Post-marketing Study (2023)

Safety data in this study indicated no extra safety concerns. Rasagiline is generally safe and well tolerated in Chinese PD patients. The safety profile and tolerability were in line with the established safety profile. Moreover, rasagiline reduced the severity of PD motor symptoms, confirming findings by previous clinical trials.
Geographical variation in total phenolics, flavonoids and antioxidant activities of Eucalyptus camaldulensis leaves in Burkina Faso (2020)

This study aimed to elucidate the effect of sampling location of Eucalyptus camaldulensis leaves on antioxidant activity, total phenolic content (TPC) and total flavonoid content (TFC). Leaves of E. camaldulensis collected at three different locations in Burkina Faso (north, central, south-west) were subjected to hydrodistillation to obtain a water extract and subsequent ethanol extraction of the solid residue. The extracts were analysed for antioxidant activity using 2,2-diphenyl-1-picryl-hydrazyl (DPPH) radical scavenging, TPC, TFC and high-performance thin layer chromatography (HPTLC) fingerprint. TPC were higher in water extracts and presented considerable variation from 129±9 to 266±4 milligram Gallic Acid Equivalent per gram of extract (mg GAE/g) with the highest value 266±4 mg GAE/g at the south-west site. This aqueous extract also showed high antioxidant activity with EC50 8.3 µg/mL. Furthermore, HPTLC fingerprint of the extracts showed both band intensity and size differences. For TFC, we found a slight differences within both water and ethanolic extracts with the highest value of 38.3 ±4.2 mg QE/g for the south-west ethanolic extract. The noticeable impact of climate on chemical variability of E. camaldulensis leaves needs to be taken into consideration for any further applications based on TPC biological activity of the extracts.

	Key words: Eucalyptus camaldulensis, total phenolic content, total flavonoid content, antioxidant activity, sample location, chemical variation.
Use of immobilized synthetic peptides for the identification of contact sites between human interleukin‐6 and its receptor (1996)

Synthetic peptides immobilized on cellulose membranes proved to be a powerful tool for the identification of sites in the cytokine IL-6 involved in receptor binding. Similarly, a region in the extracellular part of the IL-6 receptor which is important for interaction with its ligand was identified.
Photoinduced Electron Transfer Reaction of 3,3-Dimethyl-3H-pyrazoles: The Formation of Solvent Adducts through Cyclopropene Derivatives (1997)

Abstract 3,3-Dimethyl-3H-pyrazoles were photolyzed, and in the presence of 2,4,6-triphenylpyrylium tetrafluoroborate (TPP+) as a sensitizer in acetonitrile; in addition to cyclopropenes, 2H-pyrroles were obtained as solvent adducts to 1,3-radical cation intermediate.
A Two-Dimensional Unsteady Method of Characteristics Analysis of Fluid Flow Problems - MCDU 43 (1975)

Abstract : A computer code for solving two-dimensional, unsteady, inviscid, fluid-flow problems has been developed. Presented are details of the method-of- characteristics formulation, the treatment of the boundary conditions, and the numerical solution technique. In a sample problem of a cylindrical blast wave, the error to the exact solution is less than 0.05% at all points after 50 times planes of calculation.
Electro-Optical Ring Modulator: An Ultracompact Model for the Comparison and Optimization of p-n, p-i-n, and Capacitive Junction (2016)

Silicon photonics electro-optical ring modulators are key components in short-range optical interconnects, as they can be operated at low-voltage, compatible with CMOS circuit drivers. However, a full exploration of design tradeoffs is currently lacking. In this paper, a semianalytical simulation scheme is proposed for the optimization and comparison of different kinds of silicon ring modulator junction. We first describe the physical parameters used in the conventional models of active ring resonators, and apply the model to the case of carrier depletion in the well-known p-n junction. The same approach is applied to both p-i-n and capacitive junctions, and leads to a comparison of each type of modulation junction in which the strengths and weaknesses of each configuration are highlighted. We then propose a compact optimization model that directly provides the best opto-geometrical compromise between high modulation efficiency, low optical losses and large bandwidth.
Camera-Based Pose Estimation for Fixed-Wing UAVs During Cooperative Landing Maneuvers (2022)

The autonomous landing of fixed-wing unmanned aerial vehicles (UAVs) on moving unmanned ground vehicles (UGVs) demands precise spatial synchronization of both vehicle systems. To achieve this goal, using individual GNSS receivers and additional sensors for both vehicles and having the vehicles exchange their respective 6D pose via radio communication is a straightforward approach for mutual localization. However, failure of the radio communication or individual sensors can critically affect the safety of the landing maneuver without suitable additional sensors or fallback systems. In this work, we present and compare two methods for estimating the relative 6D pose between a UGV and a UAV using camera systems attached to the UGV. The first approach uses a stereo grayscale camera setup with fiducial markers on the underside of the wings of the UAV. The second approach uses a single RGB camera and a convolutional neural network (CNN) trained on synthetic data, which is combined with a pose tracking filter to improve the update rate. Requirements for the pose estimation system are an average position error below 0.5 m and an orientation angle error below 10 deg, while the update rate should be at least 20 Hz. Different experiments with a demonstrator vehicle setup are presented, showing the performance and advantages of the respective approaches. During flight experiments with eleven flyovers, the CNN-based system was consistently able to detect the UAV pose, while the marker-based system had detections in seven cases. The CNN-based system had RMS position errors between 0.19 m and 1.36 m, and RMS yaw angle errors between 1.2 deg and 7.7 deg, which is an average improvement of 0.33 m and 5.6 deg, respectively, compared to the marker-based system. In future work, the pose estimation will be tested in the control loop with an automated UAV and UGV.
Combining Linguistic Processing and Web Mining for Question Answering: ITC-irst at TREC 2004. (2004)

This paper describes the work we have been done in the last year on the DIOGENE Question Answering system developed at ITC-Irst. We present two preliminary experiments showing the possibility of integrating into DIOGENE a textual entailment engine based on entailment rules. We addressed the problem proposing both a methodology for acquiring rules from the Web and a matching algorithm for comparing dependency trees derived from the question and from documents. Although the overall results are not high, we consider this year participation at TREC as an intermediate step in view of a more complete and in depth integration of textual entailment rules into the system. We also report about the problems we encountered in maintaining the Web-based answer validation module. 1
Carbon Nanotube-Supported MoSe2 Holey Flake:Mo2C Ball Hybrids for Bifunctional pH-Universal Water Splitting (2019)

The design of cost-effective and efficient electrocatalysts for both hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) is pivotal for the molecular hydrogen (H<sub>2</sub>) production from electrochemical water splitting as a future energy source. Herein, we show that the hybridization between multiple HER- and OER-active components is effective for the design and realization of bifunctional electrocatalysts for universal water splitting, i.e., in both acidic and alkaline media. Our strategy relies on the production and characterization of MoSe<sub>2</sub> holey flake:Mo<sub>2</sub>C ball hybrids supported by single-walled carbon nanotube (SWCNT) electrocatalysts. Flakes of MoSe<sub>2</sub> are produced through hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>)-aided liquid phase exfoliation (LPE), which promotes both the exfoliation of the materials and the formation of nanopores in the flakes via chemical etching. The amount of H<sub>2</sub>O<sub>2</sub> in the solvent used for the exfoliation process is optimized to obtain ideal high ratio between edge and basal sites ratio, i.e., high-number of electrocatalytic sites. The hybridization of MoSe<sub>2</sub> flakes with commercial ball-like shaped Mo<sub>2</sub>C crystals facilitates the Volmer reaction, which works in both acidic and alkaline media. In addition, the electrochemical coupling between SWCNTs (as support) and MoSe<sub>2</sub>:Mo<sub>2</sub>C hybrids synergistically enhances both HER- and OER-activity of the native components, reaching high η<sub>10</sub> in acidic and alkaline media (0.049 and 0.089 V for HER in 0.5 M H<sub>2</sub>SO<sub>4</sub> and 1 M KOH, respectively; 0.197 and 0.241 V for OER in 0.5 M H<sub>2</sub>SO<sub>4</sub> and 1 M KOH, respectively). The exploitation of the synergistic effects occurring between multicomponent electrocatalysts, coupled with the production of the electrocatalysts themselves through scalable and cost-effective solution-processed manufacturing techniques, is promising to scale-up the production of H<sub>2</sub> via efficient water splitting for the future energy portfolio.
Effect of Temperature Conditioning on Chilling Injury of Cucumber Cotyledons (1991)

Endogenous abscisic acid levels and induced heat shock proteins were measured in tissue exposed for 6 hours to temperatures that reduced their subsequent chilling sensitivity. One-centimeter discs excised from fully expanded cotyledons of 11-day-old seedlings of cucumber (Cucumis sativus L., cv Poinsett 76) were exposed to 12.5 or 37 degrees C for 6 hours followed by 4 days at 2.5 or 12.5 degrees C. Ion leakage, a qualitative indicator of chilling injury, increased after 2 to 3 day exposure to 2.5 degrees C, but not to 12.5 degrees C, a nonchilling temperature. Exposure to 37 degrees C before chilling significantly reduced the rate of ion leakage by about 60% compared to tissue exposed to 12.5 degrees C before chilling, but slightly increased leakage compared to tissue exposed to 12.5 or 37 degrees C and held at the nonchilling temperature of 12.5 degrees C. There was no relationship between abscisic acid content following exposure to 12.5 or 37 degrees C and chilling tolerance. Five heat shock proteins, with apparent molecular mass of 25, 38, 50, 70, and 80 kilodaltons, were induced by exposure to 37 or 42 degrees C for 6 hours, and their appearance coincided with increased chilling resistance. Heat shock treatments reduced the synthesis of three proteins with apparent molecular mass of 14, 17, and 43 kilodaltons. Induction of heat shock proteins could be a possible cause of reduced chilling injury in tissue exposed to 37 or 42 degrees C.
Classification with Valid and Adaptive Coverage (2020)

Conformal inference, cross-validation+, and the jackknife+ are hold-out methods that can be combined with virtually any machine learning algorithm to construct prediction sets with guaranteed marginal coverage. In this paper, we develop specialized versions of these techniques for categorical and unordered response labels that, in addition to providing marginal coverage, are also fully adaptive to complex data distributions, in the sense that they perform favorably in terms of approximate conditional coverage compared to alternative methods. The heart of our contribution is a novel conformity score, which we explicitly demonstrate to be powerful and intuitive for classification problems, but whose underlying principle is potentially far more general. Experiments on synthetic and real data demonstrate the practical value of our theoretical guarantees, as well as the statistical advantages of the proposed methods over the existing alternatives.