gebhart/patrepeval huggingface dataset:
Aneurysm Ostium Angle: A Predictor of the Need for Stent as Assistance for Endovascular Aneurysm Coiling in Internal Carotid Artery Sidewall Aneurysms (2011)

In this small study, MOA was a useful parameter to predict the need for stent-assisted coiling in ICA sidewall aneurysms. Further prospective study of this parameter for aneurysms at multiple locations is required to determine its ultimate value.
FTSJ2, a Heat Shock-Inducible Mitochondrial Protein, Suppresses Cell Invasion and Migration (2014)

Ribosomal RNA large subunit methyltransferase J (RrmJ), an Escherichia coli heat shock protein, is responsible for 2'-O-ribose methylation in 23S rRNA. In mammals, three close homologs of RrmJ have been identified and have been designated as FTSJ1, FTSJ2 and FTSJ3; however, little is known about these genes. In this study, we characterized the mammalian FTSJ2, which was the most related protein to RrmJ in a phylogenetic analysis that had similar amino acid sequence features and tertiary protein structures of RrmJ. FTSJ2 was first identified in this study as a nucleus encoded mitochondrial protein that preserves the heat shock protein character in mammals in which the mRNA expressions was increased in porcine lung tissues and A549 cells after heat shock treatment. In addition, a recent study in non-small cell lung cancer (NSCLC) suggested that the FTSJ2 gene is located in a novel oncogenic locus. However, our results demonstrate that the expression of FTSJ2 mRNA was decreased in the more invasive subline (CL1-5) of the lung adenocarcinoma cells (CL1) compared with the less invasive subline (CL1-0), and overexpression of FTSJ2 resulted in the inhibition of cell invasion and migration in the rhabdomyosarcoma cell (TE671). In conclusion, our findings indicate that mammalian FTSJ2 is a mitochondrial ortholog of E. coli RrmJ and conserves the heat shock protein properties. Moreover, FTSJ2 possesses suppressive effects on the invasion and migration of cancer cells.
Efficient multi-barrier thin film encapsulation of OLED using alternating Al2O3 and polymer layers (2018)

Organic optoelectronic devices, especially for OLEDs, are extremely susceptibility to water vapor and oxygen which limit their widespread commercialization. In order to extend the shelf-lifetime of devices, thin film encapsulation is the most promising and challenging encapsulation process. In this study, dyad-style multilayer encapsulation structures based on alternating Al<sub>2</sub>O<sub>3</sub> layer and parylene C have been discussed as gas diffusion barriers, in which dense and pinhole-free Al<sub>2</sub>O<sub>3</sub> films were grown by atomic layer deposition (ALD) and flexible parylene C layers were deposited by chemical vapor deposition (CVD). We found the particle in ALD deposited Al<sub>2</sub>O<sub>3</sub> films process is the key killer to barrier property. The thickness of Al<sub>2</sub>O<sub>3</sub> films is the key factor which limit the amount of strain placed on barrier films. With three dyads of the optimal thickness of 30 nm Al<sub>2</sub>O<sub>3</sub> film and 500 nm parylene C, WVTR value is lower than 10<sup>-5</sup> g m<sup>-2</sup> per day. In addition, the lifetime of OLEDs with and without encapsulation was 190 h and 10 h, respectively. All the results show that this TFE structure has the effective encapsulated property and does not cause degradation of the OLED devices.
Detection of Salmonella Typhimurium from Artificially Contaminated Poultry Feed and Animal By-Products (1963)

Within recent years there has been increased interest in the possible spread of salmonellosis in poultry through feed having contaminated ingredients. The Communicable Disease Center Laboratory, Atlanta, Georgia, reported an increase in the number of Salmonella typed over the past few years that have been isolated from agricultural sources (1,6). Morehouse and Wedman (7) indicated that conclusive evidence is lacking to incriminate feed as the cause of salmonellosis in poultry. Reports of different investigators are difficult to evaluate because of a lack of standard bacteriological procedures for the examination of feedstuffs. In recent years the most intensive effort to standardize procedures has been by those concerned with Salmonella in egg products. A number of selective media have been developed, and various procedures have been proposed (9,10,13). This study was made to compare the effectiveness of several media in detecting Salmonella typhimuriumrn in artificially contaminated poultry feedstuffs.
Effects of Novel Dual GIP and GLP-1 Receptor Agonist Tirzepatide on Biomarkers of Nonalcoholic Steatohepatitis in Patients With Type 2 Diabetes (2020)

In post hoc analyses, higher tirzepatide doses significantly decreased NASH-related biomarkers and increased adiponectin in patients with T2DM.
Plasmodium sporozoite motility: an update (2011)

Plasmodium, the causative agent of malaria, employs its own actin/myosin-based motor for forward locomotion, penetration of molecular and cellular barriers, and invasion of target cells. The sporozoite is unique amongst the extracellular Plasmodium developmental forms in that it has to cross considerable distances and different tissues inside the mosquito and vertebrate hosts to ultimately reach a parenchymal liver cell, the proper target cell where to transform and replicate. Throughout this dangerous journey, the parasite alternates between being passively transported by the body fluids and using its own active cellular motility to seamlessly glide through extracellular matrix and cell barriers. But irrespective of the chosen path, the sporozoite is compelled to keep on moving at a fairly fast pace to escape destruction by host defense mechanisms. Here, we highlight and discuss recent findings collected in Plasmodium sporozoites and related parasites that shed new light on the biological significance of apicomplexan motility and on the structure and regulation of the underlying motor machinery.
Colloidal molecules and patchy particles: complementary concepts, synthesis and self-assembly (2020)

This review describes the latest advances in the synthesis and assembly of specific colloids such as the colloidal molecules as defined by van Blaaderen in 2003 and the patchy particles imagined a few years later. The two concepts are closely related because some may serve as precursors of others and vice versa. To best mimic the molecular structures, it is necessary to introduce the notions of directed binding and valence which result in the concept of patches arranged on the particle surface according to the conventional repulsion figures. The assembly of patchy particles has made it possible to reconstitute molecules and macromolecules of simple geometry. But the existence of extended assemblies of larger dimensions has been demonstrated mostly by simulation and it struggles experimentally with the purity of the batches of building blocks.
Autogenous vein bypass grafts: biological effects of mechanical dilatation and adventitial stripping in dogs. (1975)

To evaluate whether mechanical vein dilatation and stripping of adventitia at the time of harvest may adversely alter the long-term fate of autogenous vein grafts, dogs were subjected to reversed femoral vein interposition grafting with either normal veins, mechanically dilated veins, or adventitially stripped veins. Vein segments taken before grafting and veins exposed in situ but not grafted served as controls. Animals were killed at 3 months, and five vein segments in each category were evaluated for gross and microscopic changes. All grafts subjected to arterial interposition displayed marked neointimal proliferation and fibrosis of the media and adventitia. Notably, both dilated and stripped veins appeared to be similar and were indistinguishable from normal veins that had been subjected to arterial interposition for the same duration. Veins exposed in situ but not subjected to arterial flow remained essentially normal. Adverse alterations attributed to vein dilatation or adventitial stripping were not apparent and should not be invoked in the mechanism of graft failure at 3 months' duration.
123 I‐iodobenzamide‐SPECT predicts dopaminergic responsiveness in patients with de novo parkinsonism (1992)

We used 123I-iodobenzamide-single photon emission computed tomography (IBZM-SPECT) in a prospective study to investigate 38 patients with parkinsonism (Hoehn and Yahr stage I to III) not previously treated with dopamimetic drugs. Thirty-four patients only showed symptoms of Parkinson's disease, and four patients showed, in addition, subtle clinical signs of progressive supranuclear palsy or multisystem atrophy. IBZM is a dopamine D2 receptor antagonist detectable by SPECT. We compared IBZM-SPECT results with clinical response to subcutaneous injections of the D1/D2 dopamine receptor agonist apomorphine (38 patients) and long-term dopamimetic therapy (31 patients). IBZM-SPECT results predicted a positive or negative response to apomorphine in 30 of 34 patients (apomorphine response in four patients was equivocal) and response to dopamimetic therapy in 27 of 31 patients. Thus, imaging of dopamine D2 receptors using readily available IBZM-SPECT seems to distinguish between L-dopa-responsive (most likely Parkinson's disease of Lewy body type) and L-dopa-unresponsive parkinsonism in patients not previously treated with dopamimetic drugs.
Conductivity of two-component systems (1996)

Abstract We present measurements and computer simulation results on the electrical conductivity of nonconducting grains embedded in a conductive brine host. The shapes of the grains ranged from prolate-ellipsoidal (with an axis ratio of 5:1) through spherical to oblate-ellipsoidal (with an axis ratio of 1:5). The conductivity was studied as a function of porosity and packing, and Archie's cementation exponent was found to depend on porosity. We used spatially regular and random configurations with aligned and nonaligned packings. The experimental results agree well with the computer simulation data. This data set will enable extensive tests of models for calculating the anisotropic conductivity of two-component systems.
DNA typing in thirty seconds with a microfabricated device (1997)

We report the development of a practical ultrafast allelic profiling assay for the analysis of short tandem repeats (STRs) by using a highly optimized microfluidic electrophoresis device. We have achieved baseline-resolved electrophoretic separations of single-locus STR samples in 30 sec. Analyses of PCR samples containing the four loci CSF1PO, TPOX, THO1, and vWA (abbreviated as CTTv) were performed in less than 2 min. This constitutes a 10- to 100-fold improvement in speed relative to capillary or slab gel systems. The separation device consists of a microfabricated channel 45 micron x 100 micron in cross section and 26 mm in length, filled with a replaceable polyacrylamide matrix operated under denaturing conditions at 50 degrees C. A fluorescently labeled STR ladder was used as an internal standard for allele identification. Samples were prepared by standard procedures and only 4 microl was required for each analysis. The device is capable of repetitive operation and is suitable for automated high-speed and high-throughput applications.
Droplet-driven transports on superhydrophobic-patterned surface microfluidics (2011)

Droplet-based transport phenomena driven by surface tension have been explored as an automated pumping source for a number of chemical and biological applications. In this paper, we present a comprehensive theoretical and experimental investigation of unconventional droplet-based motions on a superhydrophobic-patterned surface microfluidic (S(2)M) platform. The S(2)M surfaces are monolithically fabricated using a facile two-step laser micromachining technique on regular polydimethylsiloxane (PDMS) chemistry. Unlike the traditional droplet-driven pumps built on an enclosed microfluidic network, the S(2)M network pins the liquid-solid interface of droplets to the lithographically defined wetting boundary and establishes a direct linkage between the volumetric and hydraulic measures. Moreover, diverse modes of droplet motions are theoretically determined and experimentally characterized in a bi-droplet configuration, among which several unconventional droplet-driven transport phenomena are first demonstrated. These include big-to-small droplet merging, droplet balancing, as well as bidirectional transporting, in addition to the classic small-to-big droplet transition. Furthermore, multi-stage programmable bidirectional pumping has been implemented on the S(2)M platform, according to the newly established droplet manipulation principle, to illustrate its potential use for automated biomicrofluidic and point-of-care diagnostic applications.
Optical image encryption based on diffractive imaging (2010)

In this Letter, we propose a method for optical image encryption based on diffractive imaging. An optical multiple random phase mask encoding system is applied, and one of the phase-only masks is selected and laterally translated along a preset direction during the encryption process. For image decryption, a phase retrieval algorithm is proposed to extract a high-quality plaintext. The feasibility and effectiveness of the proposed method are demonstrated by numerical results. The proposed method can provide a new strategy instead of conventional interference methods, and it may open up a new research perspective for optical image encryption.
Quality Indicators for Esophagogastroduodenoscopy (2006)

Cohen, Jonathan M.D.; Safdi, Michael A. M.D.; Deal, Stephen E. M.D.; Baron, Todd H. M.D.; Chak, Amitabh M.D.; Hoffman, Brenda M.D.; Jacobson, Brian C. M.D., M.P.H.; Mergener, Klaus M.D., Ph.D.; Petersen, Bret T. M.D.; Petrini, John L. M.D.; Rex, Douglas K. M.D.; Faigel, Douglas O. M.D., ASGE Co-Chair.; Pike, Irving M. M.D., ACG Co-Chair. Author Information
Sorting of Fruit Using near Infrared Spectroscopy: Application to a Range of Fruit and Vegetables for Soluble Solids and Dry Matter Content (2004)

The performance of a single instrumentation platform, incorporating the use of a tungsten halogen light source, body transmittance optics and a silicon photodiode array detector, and a uniform chemometric approach is reported for the application of assessment of determination of soluble solids and dry matter content of a range of fruit. Spectra were acquired at integration times of 30 ms or less, with integration time varied between fruit types to achieve a similar signal level. Calibration performance was compared in terms of root mean standard error of cross validation ( RMSECV), regression coefficient ( R), and the SDR ( SDR = SD / RMSECV ( SD is standard deviation)]. The technology was well suited to sorting on soluble solids content ( SSC) in apple ( RMSECV 0.22%, SDR &gt; 5; R 0.98), and useful, in decreasing order of accuracy, for sorting of stonefruit, mandarin, banana, melons, onions, tomato and papaya ( RMSECV 1.1%, SDR 1.6, R 0.79). The technology also performed well in sorting on dry matter content in kiwifruit ( RMSECV 0.38%, SDR &gt; 3, R 0.95), and useful, in decreasing order of accuracy, for sorting of banana, mango, avocado, tomato and potato ( RMSECV 1.0%, SDR 1.7, R 0.79). The limitations of the application of the technology to fruit sorting is discussed in terms of fruit type (“skin” thickness) and population range. For example, calibration RMSECV was only 0.20% on tomato SSC, but as population variation was low ( SD 0.30%), a poor R (0.77) and SDR (1.5) was obtained.
Dynamic configuration method of satellite time-triggered Ethernet (2020)

The continuous increase of the scale of spacenborne equipment poses urgnet demand for the enhancement to intersatellite communication capabilities. In order to adapt to the future development trend of the satellite control network, time-triggered Ethernet(TTE) with strong real-time capability, high bandwidth, and stable security has become the development direction. As the carrier of inter-satellite communication, the satellite time-triggered Ethernet must adaptively make ''network switching" operations on the transformation of network, as well as ensure that the time-efficiency of network function recovery. However, the current SMT-based scheduling algorithm is of high complexity, and there is a lack of quantitative analysis of the downtime of network devices, which cannot guide the dynamic configuration of TTE. To solve this problem, this paper presents a asynchronous method of dynamic configuration in TTE. We proposes a deterministic scheduling algorithm based on the characteristics of time-triggered messages. Additionally, a method for minimizing the downtime without affecting the communication quality is proposed. Finally, we evaluate the proposed dynamic configuration mechanism in simulations. The experimental results demonstrate the feasibility of this method, which can effectively obtain the configuration conflict time, significantly realize the seamless switch of the network status.
Comparison of outcomes in ST-segment depression and ST-segment elevation myocardial infarction patients treated with emergency PCI : data from a multicentre registry : cardiovascular topic (2012)

These data suggest that similar strategies (emergency CAG with PCI whenever feasible) should be applied to both these types of AMI.
Measurement of Subnanosecond Delay Through Multiwall Carbon-Nanotube Local Interconnects in a CMOS Integrated Circuit (2008)

Due to their excellent electrical properties and small size, metallic carbon nanotubes (CNTs) are promising materials for interconnect wires in future integrated circuits. Indeed, simulations have firmly established CNTs as strong contenders for replacing or complementing copper interconnects. In this paper, we analyze the performances of a prototype 0.25-mum CMOS digital integrated circuit with select horizontal multiwall CNT (MWCNT) interconnects. Some local interconnect wires of the prototype chip were implemented, during a post-CMOS assembly process, by single 14-mum -long metallic MWCNT with 30-nm diameter, representative of future requirements for local interconnects. We evaluate the merits and challenges of MWCNT interconnects in a realistic silicon integrated-circuit environment. We experimentally extract the subnanosecond delays of these wires to quantitatively benchmark their future potential for the first time. Furthermore, we compare our experimental results with an existing MWCNT interconnect model, as well as with the expected performances of scaled copper wires. Finally, we discuss the origin of the discrepancies between our experimental results and the modeling projections.
PHKA2 mutation spectrum in Korean patients with glycogen storage disease type IX: prevalence of deletion mutations (2016)

This study expands our knowledge of the PHKA2 mutation spectrum of GSD IX. Considering the PHKA2 mutation spectrum in Korean patients with GSD IX, molecular diagnostic methods for deletions should be conducted in conjunction with direct sequence analysis to enable accurate molecular diagnosis of this disease in the Korean population.
The effect of low-temperature plasma on bacteria as observed by repeated AFM imaging (2009)

Research on low-temperature atmospheric plasma sources (LTAPS) has grown strongly over the last few years, in part driven by possible medical 'in vivo' applications. LTAPS offer new technology for medicine and biomedical engineering. Important application examples include in situ production of reactive molecules and ions, delivery at the molecular level, contact-free and self-sterilizing devices. An important issue is the efficient bactericidal effect of LTAPS, which has already been studied widely in vitro. In spite of the many investigations, details of the plasma effect on bacteria are still largely unknown. To contribute to a better understanding of the sterilization process, we investigated the morphological changes of bacteria using atomic force microscopy before and after plasma treatment at high resolution. We examined both gram-positive and gram-negative bacteria at different plasma exposure times. Additionally, the effect of UV radiation as one agent in the plasma was investigated separately. Our results suggest that several sterilizing mechanisms exist and they proceed at different timescales.
Suppression of carotenoid synthesis in transgenic Arabidopsis cultured cells over-expressing the AHL29/SOB3 gene (2008)

Up-regulation of the Arabidopsis gene AHL29/SOB3 (At1g76500), encoding a protein with an AT-hook DNA-binding protein motif, is known to function as a suppressor of the phyB phenotype and to cause delayed senescence. We over-expressed the full-length cDNA of AHL29/SOB3 under the cauliflower mosaic virus 35S promoter in Arabidopsis suspension-cultured T87 cells. Preliminary DNA array experiments suggested down-regulation of many genes of the carotenoid synthesis pathway in the transgenic cells. Metabolite analysis with a liquid chromatography-coupled mass spectrometer demonstrated that the accumulation of the carotenoids lycopene, α-carotene, β-carotene, lutein, zeaxanthin, antheraxanthin, violaxanthin and neoxanthin was suppressed in the transgenic cells. These results suggest that up-regulation of AHL29/SOB3 down-regulates the mechanism of carotenoid biosynthesis at the transcriptional level.
Maximum Sustainable Work Rate for Five Protective Clothing Ensembles with Respect to Moisture Vapor Transmission Rate and Air Permeability (2006)

The fabrics associated with protective clothing affect heat stress, which influences productivity and risks of heat-related disorders. This study compared the work limiting effects of five protective coveralls and a semiclothed condition (t-shirt and shorts). Two fabric characteristics determined from bench tests, moisture vapor transmission rate (MVTR), and air permeability were also examined as possible predictors of ensemble performance. A progressive metabolic rate protocol was used where environmentalconditions (T(db) = 32 degrees C; T(pwb) = 26 degrees C) were held constant while treadmill speed was slowly increased. The limiting metabolic rate to just maintain thermal equilibrium was the critical point. At this point, critical speed and critical metabolic rate were noted and total evaporative resistance was calculated for each ensemble. Five acclimatized subjects wore each of the six clothing conditions in a random order. Statistically significant differences were found among the five protective garments and a semiclothed ensemble for critical treadmill speed (S(crit)), critical metabolic rate (M(crit)), and total evaporative resistance (R(e-t)). The semiclothed condition (S(crit) = 1.77 m/sec; M(crit) = 580 W; R(e-t) = 0.0099 kPa m2/W) and ensembles made from spunbonded, melt blown, spunbonded polypropylene (SMS) (1.72 m/sec; 560 W; 0.0135 kPa m2/W) and spunbonded polypropylene (1.67 m/sec; 550 W; 0.0126 kPa m2/W) were able to support higher work rates than fabrics made from Tyvek 1422-A (a nonwoven spunbonded olefin) (1.48 m/sec; 470 W; 0.0183 kPa m2/W) and a microporous film supported by spunbonded polypropylene (1.34 m/sec; 420 W; 0.0231 kPa m2/W). A tightly woven polyester ensemble (1.59 m/sec; 510 W; 0.0130 kPa m2/W) had intermediate values and was not significantly different from either group. Air permeability was a better predictor of fabric work limiting performance than MVTR. An air permeability on the order of 10,000 L/min cm2 bar would have little effect on maximum sustainable work.