gebhart/patrepeval huggingface dataset:
Enhanced Electrochemical Performance of Supercapacitors via Atomic Layer Deposition of ZnO on the Activated Carbon Electrode Material (2021)

Fabricating electrical double-layer capacitors (EDLCs) with high energy density for various applications has been of great interest in recent years. However, activated carbon (AC) electrodes are restricted to a lower operating voltage because they suffer from instability above a threshold potential window. Thus, they are limited in their energy storage. The deposition of inorganic compounds' atomic layer deposition (ALD) aiming to enhance cycling performance of supercapacitors and battery electrodes can be applied to the AC electrode materials. Here, we report on the investigation of zinc oxide (ZnO) coating strategy in terms of different pulse times of precursors, ALD cycles, and deposition temperatures to ensure high electrical conductivity and capacitance retention without blocking the micropores of the AC electrode. Crystalline ZnO phase with its optimal forming condition is obtained preferably using a longer precursor pulse time. Supercapacitors comprising AC electrodes coated with 20 cycles of ALD ZnO at 70 °C and operated in TEABF<sub>4</sub>/acetonitrile organic electrolyte show a specific capacitance of 23.13 F g<sup>-1</sup> at 5 mA cm<sup>-2</sup> and enhanced capacitance retention at 3.2 V, which well exceeds the normal working voltage of a commercial EDLC product (2.7 V). This work delivers an additional feasible approach of using ZnO ALD modification of AC materials, enhancing and promoting stable EDLC cells under high working voltages.
Three‐dimensional ultrasound diagnosis of Larsen syndrome with further characterization of neurological sequelae (2004)

Larsen syndrome consists of skeletal dysplasia with multiple joint dislocations and a characteristic facies. The basis of this abnormality is a generalized mesenchymal disorder involving connective tissues. We describe our findings in a woman who was referred at 28 weeks' gestation due to multiple fetal anomalies suspected initially at an 18-week ultrasound examination. On three-dimensional (3D) ultrasound we found the fetus had bilateral genu recurvatum. Further 3D examination at 36 weeks confirmed the lower limb anomaly and revealed facial anomalies that led to the diagnosis of Larsen syndrome. An elective Cesarean section was performed at 38 weeks' gestation to minimize neurological sequelae. Magnetic resonance imaging was performed postnatally and showed pachygyria, colpocephaly and agenesis of the corpus callosum. In this case, 3D ultrasound facilitated the prenatal diagnosis of Larsen syndrome. A careful prenatal investigation for other associated anomalies such as those of the cardiovascular or neurological systems is warranted with this diagnosis. These associated lesions are likely to have a greater impact on prognosis than the classic symptoms of Larsen syndrome and a collaborative approach is necessary to optimize delivery and postnatal management of an affected fetus.
A Chlamydomonas genomic library in yeast artificial chromosomes. (1995)

We have constructed and characterized a Chlamydomonas reinhardtii total genomic library in yeast artificial chromosomes (YACs). The library contains 7500 clones with inserts ranging in size from 100-200 kb. The representation of the library was assessed by screening one-third of it with a probe derived from the dispersed repeat, Gulliver, which occurs approximately 13 times in the genome. At least 10 of these Gulliver loci were isolated within 15 independent YACs. Two of these YACs encompass the Gulliver element designated G, which was reported to map to the uni linkage group (ULG). The end clones of these two YACs have been genetically mapped by RFLP analysis in an interspecific cross and thereby shown to be closely linked to the APM locus on the ULG. A third uni-specific YAC has also been isolated and its ends have been mapped by RFLP analysis. Genetic and RFLP analysis of these and other YACs indicates that the frequency of chimeric YACs in the library is very low. The library was constructed in a second generation vector that enables plasmid rescue of YAC end clones as well as copy number amplification of artificial chromosomes. We provide evidence that amplification of intact YACs requires a rad1:rad52 yeast strain.
Ultrasound Diagnosis of Breast Diseases (1994)

Basic Aspects of Ultrasound. Scanning Techniques. Anatomy and Normal Appearances. Diagnostic Features on Ultrasound. Benign Processes. Tumours. Benign Processes. Cysts, Benign Breast Change, Gynaecomastia. Benign Processes. Inflammation. Benign Processes. Trauma and Iatrogenic Conditions. Malignant Disease. Primary Carcinomas. Malignant Disease. Local Recurrences and Metastases/ Indications for Breast Ultrasound. Index
An on-chip voltage regulator using switched decoupling capacitors (2002)

On-chip decoupling capacitors are actively switched to suppress resonance in the power distribution system of a microprocessor. With this scheme, charge storage capacity is amplified, while instantaneous monitoring of rail activity and dynamic control of the switching response provide bandlimited on-chip voltage regulation.
Reduction of cystic cavity, promotion of axonal regeneration and sparing, and functional recovery with transplanted bone marrow stromal cell–derived Schwann cells after contusion injury to the adult rat spinal cord (2008)

Based on their findings, the authors concluded that BMSC-SC transplantation reduces the size of the cystic cavity, promotes axonal regeneration and sparing, results in hindlimb functional recovery, and can be a useful tool for spinal cord injury as a substitute for SCs.
Shape Regulation of CeO2 Nanozymes Boosts Reaction Specificity and Activity (2022)

Abstract Among reported nanozymes, CeO 2 seems to be the only transition metal oxide that can mimic phosphatase and peroxidase by catalyzing substrate dephosphorylation and oxidation (with H 2 O 2 ). However, no consensus on the key Ce species was reached in the literature using spherical CeO 2 enclosed by (111) and (100) surfaces, not to mention the further control of its reaction specificity. In this study, octahedral and cubic CeO 2 preferentially terminated by (111) and (100) surfaces were found to exhibit high reaction specificity (and activity) towards each of the above reactions. Spectroscopic evidence suggests that this is closely associated with the Lewis acidity (or electron density) of surface Ce species. The acidic Ce species on (111) surface can catalyze substrate dephosphorylation at room temperature but do not for substrate oxidation with H 2 O 2 . This correlation was further evidenced by the electron‐rich Ce species on (100) surface, hindering the first reaction while promoting the latter.
Relational One-Class Classification: A Non-Parametric Approach (2014)

One-class classification approaches have been proposed in the literature to learn classifiers from examples of only one class. But these approaches are not directly applicable to relational domains due to their reliance on a feature vector or a distance measure. We propose a non-parametric relational one-class classification approach based on first-order trees. We learn a tree-based distance measure that iteratively introduces new relational features to differentiate relational examples. We update the distance measure so as to maximize the one-class classification performance of our model. We also relate our model definition to existing work on probabilistic combination functions and density estimation. We experimentally show that our approach can discover relevant features and outperform three baseline approaches.
Population Pharmacokinetics and Exposure‐Response Analyses for the Most Frequent Adverse Events Following Treatment With Lemborexant, an Orexin Receptor Antagonist, in Subjects With Insomnia Disorder (2020)

Lemborexant is a novel orexin receptor antagonist approved in the United States and Japan for the treatment of insomnia. This article describes the population pharmacokinetics (PK) of lemborexant and the relationship of its daily steady-state exposure (C<sub>av,ss</sub> ) to the probability of most frequent treatment-emergent adverse events (TEAEs). The 12 230-observation, 1892-subject PK data set included data from 12 clinical studies with predominantly female subjects (66%) ranging in age from 18 to 88 years and from 37 to 168 kg in body weight. The 1664-subject exposure-response data set included data from 3 late-stage studies. Lemborexant pharmacokinetics were described by a 3-compartment model with combined first- and zero-order absorption with lag time and linear elimination. Oral clearance decreased with increasing body mass index (exponent, -0.428), increasing alkaline phosphatase levels (exponent, -0.118), and was 26% lower in the elderly (≥65 years). Across the adverse event analysis, the frequency of subjects experiencing TEAEs during active treatment ranged from approximately 3% to 8%, in the range estimated for placebo. With and without adjustment for age, lemborexant exposure (C<sub>av,ss</sub> ) was not a clinically meaningful linear predictor of the probability of specific TEAEs: somnolence, nasopharyngitis, flu/influenza, urinary tract infection, upper respiratory tract infection, or headache. Given the small effect sizes of covariates of the PK model and a low degree of association of lemborexant TEAEs and exposure over the range of phase 3 (therapeutic) 5- and 10-mg doses, lemborexant can be safely administered without the need for dose adjustment.
Accounting Issues in Cross-Border Securities Offerings (1994)

The influence of ethylendiamine salt of alpha-lipoic acid on the indices of iron metabolism in patients with occupational pathologies has been studied using quantitative electron spin resonance spectroscopy. In the cases of treatment in the patients suffering from hyperferremia the decrease in transferrin iron concentration in the whole blood and plasma occurs correlating with the enhancement of iron excretion from urine and decline of bilirubin level in serum. We have found that the preparation chelates iron from iron (III)-citrate complex and form stable iron (III) complexes. The conclusion is that the positive effects of lipoic acid preparation in the patients with hyperferremia at least partially could be associated with normalization of iron exchange and reduction in the labile iron pool.
Large and porous carbon sheets derived from water hyacinth for high-performance supercapacitors (2016)

Large and porous carbon sheets derived from water hyacinths owns high specific surface and desirable microstructures ensuring large specific capacitance, excellent rate capability and superior cyclic stability for high performance supercapacitors.
Novel Method of Aromatic Coupling between N-Aryl Methanesulfonamide and Thiophene Derivatives (2007)

Oxidation of N-aromatic methanesulfonamides with iodobenzene diacetate in the presence of substituted thiophene promotes interesting coupling reactions in moderate to good yields.
Hydrogen limitation—a method for controlling the performance of membrane biofilm reactor for autotrophic denitrification of wastewater (2006)

Hydrogen-driven denitrification using the fiber membrane biofilm reactor (MBfR) was evaluated for consistent operation in tertiary wastewater treatment. The possibility of controlling the process rates, as well as biofilm parameters by supplying limited amounts of electron donor (hydrogen), was tested. Limiting the hydrogen supply proved to be efficient in controlling the biofilm growth and performance of the MBfR. Denitrification rates remained unchanged for both synthetic wastewater (SWW) and real municipal wastewater (MWW) effluent as well through the fluctuations in the substrate (NO3-N) concentration. The average denitrification rates were 0.50 (+/- 0.02) g NO3-N per day per m2 for SWW and 0.59 (+/- 0.04) g NO3-N per day per m2 for MWW. Biofilm density rather than thickness was the determining factor in substrate diffusion and biofilm sloughing, ultimately determining operating stability. Limited hydrogen supply assured constant volatile solids (VS) concentration in the biofilm. It was determined that VS/TS ratio higher than 0.25 assured stable biofilm operation. Decrease of VS/TS ratio below 0.25 led to shearing of the nonbiological outer layers of the biofilm. The values of chemical oxygen demand (COD), volatile suspended solids (VSS) and total suspended solids (TSS) in the final effluent were stable and well below wastewater effluent guidelines. Substitutions of bicarbonate with gaseous carbon dioxide as the carbon source did not affect denitrification rates despite lower than optimum pH conditions.
Dechlorination of (2,4,5-trichlorophenoxy)acetic acid by anaerobic microorganisms (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDechlorination of (2,4,5-trichlorophenoxy)acetic acid by anaerobic microorganismsJoseph M. Suflita, Jean Stout, and James M. TiedjeCite this: J. Agric. Food Chem. 1984, 32, 2, 218–221Publication Date (Print):March 1, 1984Publication History Published online1 May 2002Published inissue 1 March 1984https://pubs.acs.org/doi/10.1021/jf00122a011https://doi.org/10.1021/jf00122a011research-articleACS PublicationsRequest reuse permissionsArticle Views90Altmetric-Citations44LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A barbiturate-regulated protein binding to a common sequence in the cytochrome P450 genes of rodents and bacteria. (1991)

Analyses of the 5' regulatory sequences of genes encoding barbiturate-inducible cytochromes P450BM-1 and P450BM-3 from Bacillus megaterium and of the 5' sequences of genes for barbiturate-inducible P450b and P450e of the rat revealed a string of 17 base pairs in each of the genes that shared a high degree of sequence identity. Labeled oligonucleotide probes of each of these four sequences were tested in gel retardation assays with protein obtained from B. megaterium grown either in the presence or absence of barbiturates or with protein from nuclear extracts from livers of rats left untreated or injected with phenobarbital. Each of the four 17-mers bound strongly to a single protein from bacteria grown in the absence of barbiturates, but this binding was dramatically reduced with protein from pentobarbital- or phenobarbital-grown cells. Conversely, the probes complexed weakly to one protein band from nuclear extracts from untreated rats but much more strongly with protein from phenobarbital-treated rats. Similar effects could be obtained by prolonged incubation with phenobarbital of either soluble protein from the bacteria grown in the absence of barbiturates or nuclear extract protein from untreated rats. Deletion analysis of the 5'-flanking region of the P450BM-1 gene of B. megaterium revealed a putative repressor binding site located within a 24-base pair DNA segment that included the 17-base pair sequence involved in barbiturate-regulated protein binding.
The Relationship of Lower-Limb Muscle Force to Walking Ability in Patients With Amyotrophic Lateral Sclerosis (1999)

The findings suggest there are required levels of lower-extremity muscle force for various categories of walking ability. Variations in forces within and between categories of walking ability, however, indicate the complexity of this relationship.
Oxidative stress, aging, and diseases (2018)

Reactive oxygen and nitrogen species (RONS) are produced by several endogenous and exogenous processes, and their negative effects are neutralized by antioxidant defenses. Oxidative stress occurs from the imbalance between RONS production and these antioxidant defenses. Aging is a process characterized by the progressive loss of tissue and organ function. The oxidative stress theory of aging is based on the hypothesis that age-associated functional losses are due to the accumulation of RONS-induced damages. At the same time, oxidative stress is involved in several age-related conditions (ie, cardiovascular diseases [CVDs], chronic obstructive pulmonary disease, chronic kidney disease, neurodegenerative diseases, and cancer), including sarcopenia and frailty. Different types of oxidative stress biomarkers have been identified and may provide important information about the efficacy of the treatment, guiding the selection of the most effective drugs/dose regimens for patients and, if particularly relevant from a pathophysiological point of view, acting on a specific therapeutic target. Given the important role of oxidative stress in the pathogenesis of many clinical conditions and aging, antioxidant therapy could positively affect the natural history of several diseases, but further investigation is needed to evaluate the real efficacy of these therapeutic interventions. The purpose of this paper is to provide a review of literature on this complex topic of ever increasing interest.
Measurements of Surface Contaminants and Sorbed Organics Using an Ion Trap Secondary Ion Mass Spectrometer (2012)

This chapter contains sections titled: Introduction Instrumental Description Analysis of Alkyl Methylphosphonic Acids (AMPAS) Analysis of Blister Agents Analysis of Nerve Agents Direct Sample Introduction Mass Spectrometry (DSIMS) Analysis of Surrogates in Contact with Permeable Materials Conclusions and Prospects Acknowledgment References
CPT1A in AgRP neurons is required for sex-dependent regulation of feeding and thirst (2023)

Our results highlight that fatty acid metabolism and CPT1A in AgRP neurons show marked sex differences and play a relevant role in the neuronal processes necessary for the maintenance of whole-body fluid and energy balance.
Transforming Growth Factor Beta Does Not Work Without Angiogenesis In Vivo-Reply (1989)

<h3>In Reply.</h3> —We appreciate the opportunity to respond to the comments of Dr Beranek concerning our study. While we acknowledge the possibility that neovascularization may be induced by transforming growth factor beta,<sup>1</sup>we are unable to identify the presence of retinal neovascularization in any of the experimental retinal lesions. In addition, we performed special stains using immunoperoxidase techniques for factor VIII (ie, neovascular tissue), which were also negative. Clearly, as Dr Beranek points out, angiogenesis is often an inherent part of wound repair throughout the body in general, but is not a component of retinal wound healing.<sup>2</sup> The size of a solid black region on an autoradiograph is not limited by the dimension of the individual interstitial cells since it represents a photographic exposure of an emulsion overlying the tissue. Therefore, with particularly "hot" cells, the autoradiograph can demonstrate a black mark of aggregated grains that exceeds the
Parathyroid hormone, but not vitamin D, is associated with the metabolic syndrome in morbidly obese women and men: a cross-sectional study (2009)

The PTH level, but not the vitamin D level, is an independent predictor of MS in treatment seeking morbidly obese Caucasian women and men. Randomized controlled clinical trials, including different therapeutic strategies to lower PTH, e.g. calcium/vitamin D supplementation and weight reduction, are necessary to explore any cause-and-effect relationship.
Inhibition of Nipah Virus Infection In Vivo: Targeting an Early Stage of Paramyxovirus Fusion Activation during Viral Entry (2010)

In the paramyxovirus cell entry process, receptor binding triggers conformational changes in the fusion protein (F) leading to viral and cellular membrane fusion. Peptides derived from C-terminal heptad repeat (HRC) regions in F have been shown to inhibit fusion by preventing formation of the fusogenic six-helix bundle. We recently showed that the addition of a cholesterol group to HRC peptides active against Nipah virus targets these peptides to the membrane where fusion occurs, dramatically increasing their antiviral effect. In this work, we report that unlike the untagged HRC peptides, which bind to the postulated extended intermediate state bridging the viral and cell membranes, the cholesterol tagged HRC-derived peptides interact with F before the fusion peptide inserts into the target cell membrane, thus capturing an earlier stage in the F-activation process. Furthermore, we show that cholesterol tagging renders these peptides active in vivo: the cholesterol-tagged peptides cross the blood brain barrier, and effectively prevent and treat in an established animal model what would otherwise be fatal Nipah virus encephalitis. The in vivo efficacy of cholesterol-tagged peptides, and in particular their ability to penetrate the CNS, suggests that they are promising candidates for the prevention or therapy of infection by Nipah and other lethal paramyxoviruses.
A low power wideband 2.6GHz CMOS injection-locked ring oscillator prescaler (2003)

A high speed and low power prescaler based on an injection-locked ring oscillator is presented. The proposed prescaler uses adaptive biasing to increase the locking range and to eliminate the sensitivity of the locking phenomena to temperature and process variation. The designed circuit can be used in a fractional-N frequency synthesizer. The prescaler operates properly in a temperature range of -20/spl deg/C to +100/spl deg/C and input frequency range from 2.2 GHz to 2.6 GHz in all process corners while its maximum power dissipation is 2 mW at a supply voltage of 1.5 V.
Surface acoustic wave impedance element ISM duplexer: modeling and optical analysis (2001)

Surface acoustic wave (SAW) impedance element antenna duplexers provide compact, high performance, front-end components apt for industrial fabrication. We describe investigations on the design and modeling of a compact ISM antenna duplexer fabricated on a 36 degrees YX-cut LiTaO3 substrate based on SAW impedance elements. In particular, we have performed 3-D modeling of the inductive and capacitive electromagnetic couplings caused by the package parasitics for the duplexer. The use of a 1:3 IDT structure for the reduction of the passband width is discussed. The frequency response of the duplexer is predicted with the help of circuit simulation; the modeling is refined by optimization of the model parameters to improve the fit between the measured and simulated responses. We also report scanning optical imaging of the acoustic field within the resonator structures with the help of laser interferometry; this provides insight into the loss mechanisms beyond that attainable in mere electric measurements.
Publisher Correction: The tuatara genome reveals ancient features of amniote evolution (2020)

An amendment to this paper has been published and can be accessed via a link at the top of the paper.