gebhart/patrepeval huggingface dataset:
Expression of activated H-rasval12 in nontumorigenic and non-cross-reactive syngeneic cells induces tumor antigens cross-reactive with rat mammary adenocarcinoma 13762 (1995)

Adenocarcinoma 13762 expresses tumor Ags that can induce protective immunity to tumorigenic challenge. Syngeneic fibroblast Rat1 cells transformed by expression of H-rasval12 (Rat1/ras) but not parental Rat1 cells, and p53-transformed Rat1 cells, or other syngeneic cells or tumors, can immunize rats against tumorigenic challenge of 13762 tumor. Coincident with induced resistance to 13762 tumors, immunization of rats with Rat1/ras tumor induces CD4+ T cells that cross-react with adenocarcinoma 13762 in vitro and transfer protective immunity to tumorigenic 13762 challenge in vivo. Cross-reactive tumor Ags expressed in Rat1/ras tumor are not derived from ras protein, because immunization with purified H-rasval12 protein induces protective immunity to challenge by Rat1/ras tumor but not to adenocarcinoma 13762. In addition, immunization with H-rasval12 protein induces anti-ras CD4+ T cells that are uniquely reactive with Rat1/ras tumor: anti-ras T cells are not reactive with 13762 tumor in vitro and do not confer protective immunity to challenge with 13762 tumor in vivo. Tumor Ags expressed in Ras-transformed Rat1 cells that elicit cross-protective immunity likely arise as a consequence of transformation mediated by activated ras oncogene but are not derived from the Ras protein sequence.
Zero-Delay Joint Source-Channel Coding for a Multivariate Gaussian on a Gaussian MAC (2014)

In this paper, communication of a Multivariate Gaussian over a Gaussian Multiple Access Channel is studied. Distributed zero-delay joint source-channel coding (JSCC) solutions to the problem are given. Both nonlinear and linear approaches are discussed. The performance upper bound (signal-to-distortion ratio) for arbitrary code length is also derived and Zero-delay cooperative JSCC is briefly addressed in order to provide an approximate bound on the performance of zero-delay schemes. The main contribution is a nonlinear hybrid discrete-analog JSSC scheme based on distributed quantization and a linear continuous mapping named Distributed Quantizer Linear Coder (DQLC). The DQLC has promising performance which improves with increasing correlation, and is robust against variations in noise level. The DQLC exhibits a constant gap to the performance upper bound as the signal-to-noise ratio (SNR) becomes large for any number of sources and values of correlation. Therefore it outperforms a linear solution (uncoded transmission) in any case when the SNR gets sufficiently large.
Synthesis and Crystal Structures of Bis(sulfonamido) Titanium Bis(alkoxide) Complexes:  Mechanistic Implications in the Bis(sulfonamide) Catalyzed Asymmetric Addition of Dialkylzinc Reagents to Aldehydes (1998)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTSynthesis and Crystal Structures of Bis(sulfonamido) Titanium Bis(alkoxide) Complexes: Mechanistic Implications in the Bis(sulfonamide) Catalyzed Asymmetric Addition of Dialkylzinc Reagents to AldehydesSuzy Pritchett, David H. Woodmansee, Peter Gantzel, and Patrick J. WalshView Author Information San Diego State University, San Diego, California 92182-1030 University of California, San Diego La Jolla, California 92093 Cite this: J. Am. Chem. Soc. 1998, 120, 25, 6423–6424Publication Date (Web):June 12, 1998Publication History Received13 October 1997Published online12 June 1998Published inissue 1 July 1998https://pubs.acs.org/doi/10.1021/ja973557whttps://doi.org/10.1021/ja973557wrapid-communicationACS PublicationsCopyright © 1998 American Chemical SocietyRequest reuse permissionsArticle Views856Altmetric-Citations109LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Addition reactions,Catalysts,Ligands,Reagents,Titanium Get e-Alerts
FDG-PET Imaging in Primary Bilateral Adrenal Lymphoma: A Case Report and Review of the Literature (2005)

Primary adrenal lymphoma is an extremely rare entity. Only 70 cases have been reported in the English literature. Most of the patients are elderly men with bilateral adrenal masses without extraadrenal involvement. The most common presenting symptoms are fever, weight loss, lumbar pain, and/or symptoms of adrenal insufficiency. Of the cases reported, CT, ultrasound, and MRI were the imaging modalities used to describe the lesions. FDG PET has been used successfully to differentiate benign and malignant adrenal masses. The authors report a 67-year-old man diagnosed as having primary bilateral adrenal lymphoma and having no evidence of extraadrenal spread who was evaluated from the time of diagnosis to complete remission with FDG PET scanning. The literature of this unusual neoplasm is reviewed in detail.
One-step sonochemical synthesis of a reduced graphene oxide – ZnO nanocomposite with antibacterial and antibiofouling properties (2019)

Antibacterial reduced graphene oxide – ZnO nanocomposite was synthesized by a one-step sonication method. The antibiofouling surface property of a nanocomposite incorporated polymeric membrane was high with minimum Zn<sup>2+</sup> leaching.
Antifungal activity of nanoemulsion from Cleome viscosa essential oil against food-borne pathogenic Candida albicans (2020)

Pathogenic and spoilage fungi cause enormous challenges to food related fatal infections. Plant essential oil based classical emulsions can functions as antifungal agents. To investigate the antifungal spectrum, that is the scope of the nanoemulsion composed of Cleome viscosa essential oil and Triton-x-100 fabricated by ultrasonication method. Minimum inhibitory and fungicidal concentration of essential oil nanoemulsion (EONE) was tested against food borne pathogenic C. albicans. The MIC and MFC values ranged from 16.5 to 33 µl/ml with significant reduction on biofilm of C. albicans isolates. The alteration of molecular fingerprints was confirmed by Fourier transformed infrared spectroscopy and subsequent reduction of chitin levels in cell walls was noted by spectroscopic analysis. The EONE and their bioactive compounds cause collateral damage on C. albicans cells.
IDFT-VFDM for Downlink and Uplink Decoupling (2018)

During the first phase of the deployment of 5th generation (5G) networks, new radio (NR) base station (BS) and user equipment (UE) are expected to operate alongside pre-existing 4th generation (4G) networks. One important prerequisite for this coexistence to be harmlessly achieved is that the presence of NR devices should not disrupt the service requested, delivered and obtained by the legacy long-term evolution (LTE) system. This paper proposes a solution to be adopted by NR UEs to perform an uplink transmission towards the NR BS over the same time and frequency resources as the LTE system. To guarantee the absence of interference at the LTE BS, we design a new waveform termed as inverse discrete Fourier transform-based Vandermonde-subspace frequency division multiplexing (IDFT-VFDM). This solution is characterized by two important features. First, an NR UE communicating with an NR BS through IDFT-VFDM would not generate any interference at the legacy LTE BS(s), regardless of the number of antennas present at both ends of the interference channel(s), and without requiring any hardware or software change to the legacy LTE system. Second, an IDFT-VFDM signal can always be designed in order to span the same signal bandwidth as a legacy single-carrier frequency division multiple access signal for LTE uplink communications. Numerical results assess the merit of IDFT-VFDM and confirm its potential as a candidate solution to achieve LTE/NR uplink coexistence in multi-antenna multi-user scenarios.
ChemInform Abstract: REACTIONS OF HETEROCYCLES WITH THIOPHOSGENE. PART 8. REACTIONS OF N,N′‐(BIS‐2‐ISOTHIOCYANATOPHENYL)‐N,N′‐DIFORMYL‐1,2‐DIAMINOETHANE (1980)

Abstract Das Ethan (I) reagiert mit Thiophosgen in Gegenwart von Basen zum Bisisothiocyanat (II).
Application of monoclonal antibodies to tumor diagnosis and therapy. (1983)

Monoclonal antibodies prepared by somatic cell hybridization techniques are ideal tools for the discrimination of cellular antigens and are beginning to reveal qualitative and quantitative differences in the antigenic composition of normal and malignant cells. Because these reagents are homogeneous in nature, recognize specific antigenic determinants, and can be mass produced, monoclonal antibodies have important clinical applications in the detection and early diagnosis of cancer, in staging procedures, and in therapeutic trials. In addition, many of these reagents have the capacity to distinguish between different types of human tumors and will be useful in the refinement of histopathologic classification schema. Monoclonal antibodies with varying degrees of specificity have already been produced against a variety of human and animal tumors. In this review, the technical aspects of monoclonal antibody production and the clinical and biologic application of these reagents are highlighted in order to demonstrate the potential of monoclonal antibodies as tools for the immunodiagnosis and therapy of malignant disease.
Fabrication of Low-Cost Large-Volume Ceramic A<sub>2</sub>HfX<sub>6</sub> (A= Cs or Tl, X = Cl, Br, or I) Scintillators for Gamma Ray Detection (SBIR Phase I Final Technical Report) (2021)

Scintillator crystals play an important role in the radiation detection field. Widespread use of scintillators as gamma-ray detectors is largely generated by their extensive availability and tunable properties, such high light output, high stopping power (Zeff), fast decay time, and good proportionality. Additionally, the cost for manufacturing a scintillation detector like NaI:Tl is usually considerably lower than the cost for manufacturing a semiconductor detector like CdZnTe. Because there is no such thing as an ideal scintillation material, an application requiring certain detection characteristics may incorporate a scintillator tailored to its specific properties. The vast variety of applications and requirements necessitates more research into new scintillation materials and/or better methods of producing existing materials.The goal of this project was to grow low cost and environmentally stable inorganic transparent ceramic scintillators with excellent gamma ray resolution, excellent energy proportionality, excellent detection efficiency due to high density (>5 g/cm3) and very high Zeff (55-80), and good light yields (>40,000 ph/MeV). In Phase I Xtallized Intelligence, Inc. (XI, Inc) developed a novel ceramic fabrication technique to produce low cost and environmentally stable highly efficient inorganic transparent ceramic scintillators of various dimensions. XI, Inc., collaborating with Fisk University (Fisk), investigated the scintillation properties of these new ceramic scintillators and compared them to in their single crystal counterparts. The results of this Phase I project show that successful production of high-quality inorganic halide ceramic scintillators Cs2HfCl6 (CHC) and Tl2HfCl6 (THC). Both ceramic CHC and THC scintillators have achieved good performance close to the performance of their single crystal counterparts. Fabricating these inorganic ceramic scintillators mitigate many issues encountered during conventional bulk crystal growth by melt methods. Additional benefits of the ceramic fabrication technique include high production yield, low production cost, fast production time, and no material waste Inorganic transparent ceramic scintillators produced in this project will enhance cost effectiveness at the instrument level based on low projected cost of the proposed compounds, as much smaller crystal sizes would be required to achieve similar efficiency as current radioisotope identification devices (RIID’s) used in homeland security applications as well as spectrometers in high energy physics applications.
ChemInform Abstract: FIVE‐COORDINATED COMPLEXES OF OSMIUM(VIII) AND RHENIUM(VII). CRYSTAL STRUCTURE OF PPH4(OSO4CL).CH2CL2 (1985)

Abstract Aus Lösungen von 0504 bzw. ReO 3 Cl in Dichlormethan und Ph 4 PCl bzw. Ph 4 PN 3 entstehen die Komplexe (I) und (II) mit fünffach koordiniertem Metallatom.
Subjective quality evaluation of different intraframe adaptive coding schemes, based on orthogonal transformations (2005)

This paper describes a subjective test for comparing different video intraframe coding methods based on adaptive orthogonal transformations. A set of images were objectively measured, in terms of mean square error, by means of computer simulation using a 16×16 Discrete Cosine Transform (DCT) in the following situations: - non adaptive transform coding - adaptive coding obtained through multiplicative coefficient for the quantiser level, according to the activity classes - adaptive coding with a constant mean square error per sub-block. Subjective and objective measures show a low correlation if a non adaptive coding scheme is used, while the correlation is higher if adaptive coding schemes are used. In particular, the uniform impairment distribution (the same quantisation error for each block) supplies a very high correlation between the two measures. Subjective evaluations were carried out using a SSR (Single Stimulus Rating) method; results are presented in terms of mean and standard deviation. Analysis of variance (ANOVA) was also performed to evaluate factor and interaction contribution to variability.
Beyond Costs: Pragmatic Considerations for Pooling of SARS-CoV-2 Test Samples for Nursing Home Surveillance (2023)

Pooling of samples can increase throughput and reduce costs for large-scale SARS-CoV-2 testing when incidence is low. In a cross-sectional study of serial SARS-CoV-2 sampling of staff and residents at three nursing homes, laboratory labor constraints limited the feasibility of pooling prior to the maximal incidence that favored cost savings. <b>IMPORTANCE</b> This study highlights the pragmatic considerations surrounding SARS-CoV-2 sample pooling beyond accuracy and costs. We performed a cost analysis to determine the percent positivity at which pooling would reduce costs versus single testing. We found that the need for a stable amount of daily work hours staffed by a highly trained workforce was a major limitation in pooling as test positivity increased. For the COVID-19 pandemic and future pandemic threats, laboratories should carefully consider the thresholds at which sample pooling is beneficial, with a particular focus on the impact on laboratory staff.
Protection by Hypothermia of Hypoxia-Induced Inhibition of Neurogenic Vasodilation in Porcine Cerebral Arteries (2003)

Porcine cerebral arterial strips denuded of the endothelium responded to transmural electrical stimulation (5 Hz for 40 s) with a relaxation, which was abolished by tetrodotoxin and N (G)-nitro-L-arginine, a NO synthase inhibitor. Lowering the temperature of the bathing media from 37 degrees C to 33 degrees C or 25 degrees C potentiated the response to nerve stimulation, but did not affect relaxations induced by NO applied exogenously. Hypoxia suppressed the stimulation-induced relaxation at 37 degrees C, but hypothermia blunted the inhibitory effect of hypoxia in a temperature-dependent manner. It is concluded that hypothermia augments vasodilatation associated with nitroxidergic (nitrergic) nerve activation possibly by increasing the production of NO from L-arginine and, in addition, prevents impairment of NO production by hypoxia. These mechanisms likely explain how hypothermia protects nerve cells against hypoxia. Inhibitions of cyclic GMP phosphodiesterase and of superoxide production by hypoxia do not seem to participate in the action of hypothermia. Mechanisms underlying its protective action remain to be ascertained.
Complexing Behaviour of Schiff Bases Derived from 3-Acetyl-4-Hydroxy-6-Methyl-2H-Pyran-2-One (1992)

Abstract By reaction of 3-acetyl-4-hydroxy-6-raethyl-2H-pyran-2-one (HDh, dehydroacetic acid) with H2NR (R = Me, nPr or nBu) and HN(CH2CH2NH2)2 the related Schiff bases HDHR and H2Dh2T were obtained. All ligands react with uranyl nitrate yielding 1 : 2 adducts. In the uranyl acetate-HDhR systems adduct formation and ligand deprotonation should occur, depending on solvent, reaction time and hydration, whereas H2Dh2T undergoes total deprotonation in the presence of uranyl acetate to give [UO2(Dh2T)]. Ligands and complexes have been characterized by ir and nmr (1H and 13C) spectroscopy and, in some cases, by thermogravimetric measurements. The action of the amines on the preformed [UO2(Dh)2] complex is discussed.
Experiments with Fractionated X-ray Treatment of the Skin of Pigs. I—Fractionation up to 28 Days (1963)

Experiments have been carried out to compare the skin reactions in pigs produced by various regimes of fractionated irradiation with X rays, extending up to 28 days. A total of 27 X-ray fields were applied to two pigs. The results show that the major factor which determines the skin response is the size (or number) of the fractions, i.e. the shape of the dose—effect curve. This factor is found to explain approximately five-sixths of the increase of total dose required to produce a given reaction when the dose is divided into five fractions. The remaining one-sixth of the increase is due to tissue repair or repopulation occurring between five and 28 days. The implication in radiotherapy is as follows. If fractionated treatments using fewer and larger fractions are given over the same overall time as a “daily” regime, it is suggested that care must be taken to reduce the total dose below that used in the daily regime, in order to avoid greater skin damage.
Energy Saving on a Full-Size Wheel Loader Through Variable Load Sense Margin Control (2021)

Abstract This paper presents the formulation of a variable load sense control strategy suitable to achieve power savings in hydraulic systems using postcompensated load sensing (LS) hydraulic control architectures. Such architecture is typical in off-road construction machinery. The paper also describes the application of the proposed control strategy referred to as variable load sensing margin (VLM) on a full-size wheel loader. The paper first presents the rationale for the proposed strategy, showing how the state-of-the-art LS architecture present in commercial machines has a margin for lowering the throttling losses present at the control valves. A feedforward controller, derived from an empirical study on a reference vehicle, is used to control the flow to the front-end loader functions. Test results show improvements of the hydraulic power consumption up to 45%, based on the commanded speed of each front-end loader actuator. The paper also describes a gain scheduling pressure feedback control strategy, which is used to allow controlling also functions that include priority. For the case of off-road vehicles, this is typically the steering function. The experimental results show good performances with an error in controlled velocity below 5%, which is achieved when the front-end loader functions are used concurrently with the steering.
Is magnesium content in erythrocytes suitable for evaluating cation retention after oral physiological supplementation in marginally magnesium-deficient subjects? (1993)

In this study, the effects of oral magnesium supplementation were evaluated on plasma, erythrocyte, and urinary cation levels. The study was carried out with an open, cross-over and randomized design. Healthy subjects received two sachets per day of magnesium (366 mg Mg2+/d) for two 28 d cycles, separated by a 3-week washout interval. Magnesium concentrations were measured before the supplementation and at weekly intervals during the treatment. Urinary excretion of Mg was significantly increased during supplementation, with no differences among the weeks examined. Only small increases in plasma magnesium occurred, and values returned to the prestudy levels before the end of supplementation. The increase in erythrocyte magnesium, however, was statistically significant; this trend suggests the existence of a saturable mechanisms, which prevents any possible magnesium overload during oral supplementation. We conclude that erythrocytes might be considered a suitable index for evaluating the bioavailability of magnesium salts in marginally magnesium-deficient subjects.
MONOCLONAL ANTIBODY‐BASED ELISAS FOR THE DETECTION OF BACTERIAL SPORES 1 (1998)

Abstract Monoclonal antibodies against bacterial spores were used to develop ELISAs to detect a range of spores. ELISAs utilizing anti‐ Bacillus spore antibodies detected spores of Bacillus megaterium ATCC 12872, Bacillus stearothermophilus ATCC 7953, Bacillus subtilis var. globigii and Bacillus cereus T. They did not detect Bacillus subtilis A, Bacillus coagulans ATCC 56177 or Bacillus licheniformis ATCC 9789. One ELISA utilizing anti‐ Clostridium spore antibodies detected spores of Desulfotomaculum nigrificans ATCC 7946, Clostridium perfringens ATCC 3624 and B. stearothermophilus ATCC 7953, but not spores of Clostridum sporogenes PA3679 or Clostridium botulinum 62A. Whole milk, skim milk, gelatin and starch all interfered to some degree with the abilities of the assays to detect spores. Neither centrifugation nor immunomagnetic bead separation provided sufficient concentration of spores from the food matrix to be applicable to the ELISAs developed. These results demonstrate the ability to detect a range of spores using monoclonal antibody‐based ELISAs. Such assays may, however, be limited by sensitivity and interference from food components.
E-cadherin loss alters cytoskeletal organization and adhesion in non-malignant breast cells but is insufficient to induce an epithelial-mesenchymal transition (2014)

Overall, our results demonstrated that E-cadherin loss alone was insufficient to induce an EMT or enhance transforming potential in the non-tumorigenic MCF10A cells but was associated with broad transcriptional changes associated with tissue remodelling.
Russian impressions (1990)

In May 1989, as a member of an RNIB delegation, the author visited Moscow and Leningrad at the invitation of the All-Russia Association o f the Blind (VOS), with the aim of gaining some impression of services for the blind in the Soviet Union. This article describes some o f his paradoxical findings.