gebhart/patrepeval huggingface dataset:
A PE Protein Expressed by Mycobacterium avium Is an Effective T-Cell Immunogen (2005)

Infection of mice with Mycobacterium avium or immunization with a novel PE gene expressed by M. avium (MaPE) showed that a dominant T-cell immune response was elicited. Immunization with an MaPE DNA vaccine protected mice against an aerosol challenge with Mycobacterium tuberculosis, suggesting that mycobacteria express PE antigens with cross-protective T-cell epitopes.
Quantitative computed tomography assessment of bronchiolitis obliterans syndrome after lung transplantation (2017)

BOS is characterized by central airway dilation and vascular remodeling, the degree of which is correlated to decrements in lung function. Our data suggest that progressive BOS is a pathologic process that affects both the central and distal airways.
Etude des surfaces de début de transformation des alliages à mémoire de forme anisotropes (2005)

Les propriétés des Alliages à Mémoire de Forme (AMF) sont dues à une transformation de phase solide-solide appelée transformation martensitique. Pour des températures supérieures à Af (Austénite finish) toutes les déformations mécaniques sont réversibles : c’est ce qu’on appelle la pseudo élasticité. Ce comportement n’est pas facile à modéliser en 3D bien que les phénomènes 1D soient bien connus. Par conséquent, il est nécessaire de définir une contrainte équivalente de début de transformation pour les AMF. Par ailleurs, Arbab Chirani et Patoor et Lexcellent font remarquer que la texture initiale des AMF a une influence forte sur la forme de ces surfaces seuil de transformation. A partir de détections de surfaces seuil expérimentales, nous définirons une contrainte équivalente pour les AMF tant isotropes qu’anisotropes.
Theoretical evaluation of Brillouin dynamic grating length localized by optical correlation domain technique through reflection spectrum simulation (2017)

We derive formulae based on Fourier transformation to calculate the reflection spectrum of a Brillouin dynamic grating (BDG), which is localized along an optical fiber by an optical correlation domain technique. First, we calculate the typical reflection spectra of the BDG localized by the technique and confirm the validity of the formulae by showing coincidence with previous theoretical or experimental works. Next, we evaluate theoretically the spatial resolution in the BDG distributed measurement by the technique, through simulations considering different strained fiber lengths. It is confirmed theoretically, for the first time, that the resolution in the BDG measurement is worse than that for the Brillouin gain spectrum.
Solid phase microextraction with analysis by gas chromatography to determine short term hydrogen cyanide concentrations in a field setting (2002)

Occupational air concentration ceiling standards should not be exceeded during any part of a working exposure. Air sampling with pumps, and filters or sorbent tubes may be coupled to methods such as gas chromatography for definitive identification of occupational air contaminants. With such methods, 15-minute sample durations are common for ceiling standard comparisons (to trap sufficient analyte for detection) giving a 15-minute time-weighted average, and not an instantaneous concentration. We used 2-minute duration solid phase microextraction (SPME) field sampling, followed later by gas chromatography with a nitrogen-phosphorous detector (GC/NPD) to detect, identify, and quantify airborne hydrogen cyanide (HCN) concentrations encountered in a field setting. The presence of HCN was confirmed in the atmosphere sampled by SPME field sampling followed by gas chromatography with mass spectrometric detection. The HCN-contaminated atmosphere was from two CS riot control canisters actuated in an enclosed building. With four simultaneous SPME field samples and GC/NPD analysis, the coefficient of variation associated with the HCN peak areas for the samples was 17%, and the HCN concentrations measured ranged from about 12 to 19 ppm. Acetonitrile and acrylonitrile were also detected as volatile nitrogen-containing air contaminants dispersed along with the CS, although their concentrations were not determined.
Emergency transjugular intrahepatic portasystemic stent shunts to control acute variceal haemorrhage resistantg to sclerotherapy (1994)

Objective: To prospectively assess the efficacy and outcome of emergency transjugular intrahepatic portasystemic stent shunts (TIPSS) in patients with acute variceal haemorrhage resistant to sclerotherapy. Design: Patients in whom active variceal haemorrhage was observed at endoscopy were treated initially with sclerotherapy. If this failed to control bleeding, emergency TIPSS were undertaken. Patients: Thirteen patients underwent emergency TIPSS during an 18-month period. Main outcome measures: Survival, re-bleeding, disturbance of liver function and the occurrence of post-TIPSS encephalopathy. Results: TIPSS were successfully performed in 11 out of 13 patients
Ultra wide band monopole planar MIMO antenna for portable devices (2017)

A Ultra Wide Band MIMO Antenna is designed whose length is 26mm and the width is 40mm. Its has a features of two planar monopole which is micro strip-fed, to achieve the good isolation. The extended ground stubs are combined in the ground plane on the other face to enhance isolation and increase impedance bandwidth. To form a common ground by ground planes are connected together by using a short ground strip. Performance analysis of an antenna is analyzed using the various parameters like reflection coefficient, radiation pattern, efficiency. The designed antenna is operates with in 3.1 to 10.6GHZ, for portable devices applications with lower mutual coupling loss and the envelope correlation coefficient is less than 0.2. This type of antenna is widely used in UWB portable applications.
Two types of brown adipose tissue in humans (2013)

During the last years the existence of metabolically active brown adipose tissue in adult humans has been widely accepted by the research community. Its unique ability to dissipate chemical energy stored in triglycerides as heat makes it an attractive target for new drugs against obesity and its related diseases. Hence the tissue is now subject to intense research, the hypothesis being that an expansion and/or activation of the tissue is associated with a healthy metabolic phenotype. Animal studies provide evidence for the existence of at least two types of brown adipocytes. Apart from the classical brown adipocyte that is found primarily in the interscapular region where it constitutes a thermogenic organ, a second type of brown adipocyte, the so-called beige adipocyte, can appear within white adipose tissue depots. The fact that the two cell types develop from different precursors suggests that they might be recruited and stimulated by different cues and therefore represent two distinct targets for therapeutic intervention. The aim of this commentary is to discuss recent work addressing the question whether also humans possess two types of brown adipocytes and to highlight some issues when looking for molecular markers for such cells.
CH3 and CH Densities in a Diamond Growth DC Discharge (1995)

Abstract A highly sensitive multi‐element optical absorption technique is used to measure the absolute column density of both CH 3 and CH radicals in a dc hollow cathode plasma‐assisted chemical vapor deposition (CVD) system with CH 4 and H 2 used as the input gases. The plasma gas temperature is determined at different spatial points using the H 2 emission spectrum near 460 nm. The spatial maps of the temperature and the radical densities provide information on the chemical processes taking place in the discharge. The CH 3 and CH radical density measurements made in the dc discharge system are compared with similar measurements made in a hot filament CVD system. The [H]/[H 2 ] ratio is derived from the CH 3 and CH densities using an analysis based on partial thermodynamic equilibrium of the single carbon hydrocarbon abstraction reactions.
Hydrophobic Interactions Contribute to Conformational Stabilization of Endoglycoceramidase II by Mechanism-Based Probes (2016)

Small compound active site interactors receive considerable attention for their ability to positively influence the fold of glycosidases. Endoglycoceramidase II (EGCII) from Rhodococcus sp. is an endo-β-glucosidase releasing the complete glycan from ceramide in glycosphingolipids. Cleavage of the β-glycosidic linkage between glucose and ceramide is also catalyzed by glucocerebrosidase (GBA), the exo-β-glucosidase deficient in Gaucher disease. We demonstrate that established β-glucoside-configured cyclophellitol-type activity-based probes (ABPs) for GBA also are effective, mechanism-based, and irreversible inhibitors of EGCII. The stability of EGCII is markedly enhanced by formation of covalent complexes with cyclophellitol ABPs substituted with hydrophobic moieties, as evidenced by an increased melting temperature, resistance against tryptic digestion, changes in (15)N-(1)H transverse relaxation optimized spectroscopy spectra of the [(15)N]Leu-labeled enzyme, and relative hydrophobicity as determined by 8-anilino-1-naphthalenesulfonic acid fluorescence. The stabilization of EGCII conformation correlates with the shape and hydrophobicity of the substituents of the ABPs. We conclude that the amphipathic active site binders with aliphatic moieties act as a "hydrophobic zipper" on the flexible EGCII protein structure.
Flexible Visible–Infrared Metamaterials and Their Applications in Highly Sensitive Chemical and Biological Sensing (2011)

Flexible electronic and photonic devices have been demonstrated in the past decade, with significant promise in low-cost, light-weighted, transparent, biocompatible, and portable devices for a wide range of applications. Herein, we demonstrate a flexible metamaterial (Metaflex)-based photonic device operating in the visible-IR regime, which shows potential applications in high sensitivity strain, biological and chemical sensing. The metamaterial structure, consisting of split ring resonators (SRRs) of 30 nm thick Au or Ag, has been fabricated on poly(ethylene naphthalate) substrates with the least line width of ∼30 nm by electron beam lithography. The absorption resonances can be tuned from middle IR to visible range. The Ag U-shaped SRRs metamaterials exhibit an electric resonance of ∼542 nm and a magnetic resonance of ∼756 nm. Both the electric and magnetic resonance modes show highly sensitive responses to out-of-plane bending strain, surrounding dielectric media, and surface chemical environment. Due to the electric and magnetic field coupling, the magnetic response gives a sensitivity as high as 436 nm/RIU. Our Metaflex devices show superior responses with a shift of magnetic resonance of 4.5 nm/nM for nonspecific bovine serum albumin protein binding and 65 nm for a self-assembled monolayer of 2-naphthalenethiol, respectively, suggesting considerable promise in flexible and transparent photonic devices for chemical and biological sensing.
Biphasic denaturation of human albumin due to ligand redistribution during unfolding. (1988)

Denaturation of defatted human albumin monomer, monitored by differential scanning calorimetry, is monophasic as reflected by the single, resulting endotherm. With low levels of various ligands, biphasic or monophasic unfolding processes are manifested as bimodal or unimodal thermograms, respectively. The greater the affinity of native protein for ligand, the greater is the tendency for biphasic denaturation. We propose that such a biphasic unfolding process arises from a substantial increase in stability (transition temperature) of remaining native protein during denaturation. This increase in stability derives from the free energy of ligand binding becoming more negative due to the release of high affinity ligand by unfolding protein. The tendency for biphasic denaturation is greatest at low (subsaturating) levels of ligand where greatest increases in stability occur. Biphasic unfolding arising from such ligand redistribution results from denaturation of different kinds of protein molecules, ligand-poor and ligand-rich species, and not from sequential unfolding of domains within the same molecule. Differentiating between these two mechanisms is necessary for the correct interpretation of biphasic denaturation data. Furthermore, biphasic unfolding due to ligand redistribution occurs independently of the means used to effect denaturation. The maximum increase in stability due to ligand binding relative to the stability of defatted albumin monomer alone occurs with the intermediate affinity ligand octanoate (22 degrees C) and not with the high affinity ligand hexadecanoate (15 degrees C). This indicates a much greater affinity of denatured albumin for hexadecanoate since increase in stability derives from the difference between free energy of ligand binding to folded and unfolded protein forms.
Impairment of the hatching process following IVF in the human and improvement of implantation by assisting hatching using micromanipulation (1990)

Journal Article Impairment of the hatching process following IVF in the human and improvement of implantation by assisting hatching using micromanipulation Get access Jacques Cohen, Jacques Cohen 1 2Gamete and Embryo Research Laboratory, Department of Gynecology and Obstetrics, Emory University School of MedicineAtlanta, GA, USA 1To whom correspondence should be addressed at: Center for Reproductive Medicine and Infertility, Cornell University Medical College, HT-330, 505 East 70 Street, New York, NY 10021, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar Carlene Elsner, Carlene Elsner Search for other works by this author on: Oxford Academic PubMed Google Scholar Hilton Kort, Hilton Kort Search for other works by this author on: Oxford Academic PubMed Google Scholar Henry Malter, Henry Malter 2Gamete and Embryo Research Laboratory, Department of Gynecology and Obstetrics, Emory University School of MedicineAtlanta, GA, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar Joe Massey, Joe Massey Search for other works by this author on: Oxford Academic PubMed Google Scholar Mary Pat Mayer, Mary Pat Mayer Search for other works by this author on: Oxford Academic PubMed Google Scholar Klaus Wiemer Klaus Wiemer Search for other works by this author on: Oxford Academic PubMed Google Scholar Human Reproduction, Volume 5, Issue 1, 1 January 1990, Pages 7–13, https://doi.org/10.1093/oxfordjournals.humrep.a137044 Published: 01 January 1990 Article history Received: 18 September 1989 Accepted: 04 October 1989 Published: 01 January 1990
All-Organic Humidity Sensing Films with Electrical Detection Principle Suitable to Biomedical Applications (2012)

The humidity sensing layer of the molecular (BEDT-TTF)-based metal was chemically deposited on the surface of a polycarbonate (PC) film [BEDT-TTF = bis(ethylenedithio)tetrathia-fulvalene]. The relative humidity (RH) tests carried out at 25 and 40 oC showed that the electrical response of the developed film to RH changes is a well-definite and reproducible signal: the resistance of the film increases by 15% when relative humidity changes from 20 to 90%. The electric transport, electro-mechanical and mechanical properties of the sensing film demonstrate that it has many advantages, some of which ideally comply with the Health Information Technology requirements applicable for sensors, to state a few of them: lightweight, flexibility, electrical detection principle, long-term stability and simple one-stage synthetic procedure carried out at ambient conditions.
An experimental study of particle migration in pipe flow of viscoelastic fluids (1996)

This paper reports experiments on particle migration in viscoelastic fluids used in hydraulic fracturing. It is found that particle migration in such fluids is controlled by the elastic properties of the suspending fluid and the shear rate gradient. In fluids with low but measurable normal stresses and dominant shear‐thinning properties, particles migrate to regions of lower shear rate. Migration is fast initially, but slows down rapidly over a short distance. For these fluids the bulk migration velocity correlates with the product of the Weissenberg number and the mean shear rate gradient. In contrast, highly elastic fluids with relaxation times well above one second and shear‐thickening properties at low shear rates, flow with a central plug region or slip at the wall, producing little or no migration.
Synthesis and Active Oxygen Generation by New Emodin Derivatives and Their Gonadotropin-Releasing Hormone Conjugates (2006)

In an attempt to develop efficient chemotherapeutic agents targeted at malignant cells that express receptors, we synthesized five new emodin derivatives and their gonadotropin-releasing hormone (GnRH) conjugates to be used as potential photoactive conjugates. Emodin was modified at its hydroxy groups and included different spacers for conjugation of the peptide. We used electron spin resonance (ESR) and spin trapping techniques to study the light-stimulated redox properties of the emodin derivatives and their GnRH conjugates. Upon irradiation, all new emodin derivatives and their conjugates stimulated the formation of singlet oxygen, that is, (1)O(2), and oxygen radicals, that is, O(2)(-)(*) and OH(*). However, substantial differences were found between the tested derivatives as to the efficacy of reactive oxygen species (ROS) production. Because of its superior ROS production properties, [d-Lys(6)(MeoEmo)]GnRH was selected as a leading conjugate. En-route to evaluate its targeting capacity, this potentially cytotoxic conjugate was tested in vitro to determine its hormonal activity and binding affinity to GnRH receptors.
Long-term Immunogenicity and Immune Memory After Two Doses of the Adult Formulation of a Combined Hepatitis A and B Vaccine in Children 1 to 11 Years of Age (2011)

Long-term persistence of antibodies against hepatitis A and B (anti-HAV and anti-HBs) were evaluated in 1- to 11-year-old children following 2 doses (0, 6 months) of hepatitis A and B vaccine. Ten years postvaccination, all subjects were anti-HAV seropositive (≥15 mIU/mL), 81.7% had anti-HBs antibody concentrations ≥10 mIU/mL. All subjects with anti-HBs concentrations <10 mIU/mL, mounted a vigorous anamnestic response to an HBV vaccine challenge dose indicating the presence of immunologic memory against hepatitis B.
Detection of lameness and determination of the affected forelimb in horses by use of continuous wavelet transformation and neural network classification of kinematic data (2003)

Wavelet transformation of gait data extracts information that is important for the detection and differentiation of forelimb lameness of horses. All of the necessary information to detect lameness and differentiate the side of lameness can be obtained by observation of vertical head movement in concert with movement of the foot of 1 forelimb.
Remote Participation‐Assisted Synthesis of β‐Mannosides. (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
Role of dendritic cell maturation factors produced by human invariant NKT cells in immune tolerance (2016)

In this study, we used the culture supernatant of iNKT cells to identify human myeloid DC maturation factors produced by human CD4<sup>+</sup> iNKT cells. S100A8 had a strong maturation effect. Notably, the recombinant S100A8 protein displayed properties of DC maturation functioning, and the induction of DC differentiation by both the purified and the recombinant protein were blocked by anti-S100A8 and anti-TLR-4 mAbs. DC differentiation induced by anti-major histocompatibility complex class II/CD1d Ab, S100A8, or both was qualitatively indistinguishable from that induced by the coculture of DCs and iNKT cells or via culture supplementation with supernatants from activated CD4<sup>+</sup> iNKT cells. S100A8 also induced CD4<sup>+</sup>/CD25<sup>+</sup>/Foxp3<sup>+</sup> T<sub>reg</sub> cells from naïve T cells. S100A8 may contribute to DC differentiation by elevating transcription factors or activating transcription factor-2, heat shock factor-1, or both, in mature DCs. S100A8 is a novel candidate iNKT cell-dependent DC maturation factor.
Environmental and genetic factors in etiology of orofacial clefts in Argentina (1997)

The Netherlands1
‘Divergent male ontogenies’ in Aphelinidae (Hymenoptera: Chalcidoidea): a simplified classification and a suggested evolutionary sequence (1983)

A classification of the different types of divergent male ontogeny in Aphelinidae is proposed to replace the little known and cumbersome systems previously published. All the Aphelinidae in which conspecific males and females have different host relationships, i.e. those that have divergent ontogenies, are here designated heteronomous parasitoids. Females of these species are primary endoparasitoids of Homoptera. The males of (i) diphagous parasitoids are primary ectoparasitoids of the same host species exploited by their females, (ii) heteronomous hyperparasitoids develop hyperparasitically, and (iii) heterotrophic species are endoparasitoids of lepidopterous eggs. Heteronomous hyperparasitoids can be classified further as obligate autoparasitoids, facultative autoparasitoids or alloparasitoids. All the species of heteronomous aphelinids whose biologies are known are listed according to the new classification, and the evolutionary sequence of these unusual host relationships is discussed.
Significance of tissue anisotropy in optical tomography of the infant brain (2007)

We study the effect of tissue anisotropy in optical tomography of neonates. A Monte Carlo method capable of modeling photon migration in an arbitrary 3D tissue model with spatially varying optical properties and tissue anisotropy is used for simulating measurements of neonates. Anatomical and diffusion tensor magnetic resonance imaging of neonates are used for creating the anatomical models. We find that tissue anisotropy affects the measured signal and the pattern of sensitivity in optical measurements.
Excited-State Electronic Structure of Conjugated Oligomers and Polymers:  A Quantum-Chemical Approach to Optical Phenomena (1999)

ADVERTISEMENT RETURN TO ISSUEPREVArticleExcited-State Electronic Structure of Conjugated Oligomers and Polymers: A Quantum-Chemical Approach to Optical PhenomenaJean-Luc Brédas, Jérôme Cornil, David Beljonne, Donizetti A. dos Santos, and Zhigang ShuaiView Author Information Service de Chimie des Matériaux Nouveaux, Centre de Recherche en Electronique et Photonique Moléculaires, Université de Mons-Hainaut, Place du Parc 20, B-7000 Mons, Belgium Cite this: Acc. Chem. Res. 1999, 32, 3, 267–276Publication Date (Web):January 20, 1999Publication History Received10 April 1998Published online20 January 1999Published inissue 1 March 1999https://pubs.acs.org/doi/10.1021/ar9800338https://doi.org/10.1021/ar9800338research-articleACS PublicationsCopyright © 1999 American Chemical SocietyRequest reuse permissionsArticle Views2552Altmetric-Citations273LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Absorption,Excited states,Molecules,Oligomers,Wave function Get e-Alerts