gebhart/patrepeval huggingface dataset:
Onlymobiles.com: Redefine the Pricing Strategy (2019)

Mr. Shrutam Desai, the 38-year-old founder of Onlymobiles.com, was always ahead of the market trend. His love for travelling exposed him to various geographies, demographics and cultures and as a result, he was always ahead of the market curve in predicting the market dynamics. Onlymobiles. com was competing with hundreds of online as well offline retailers in the mobile phones and accessories market. Onlymobiles.com, were selling mobile and smart phones of smaller ticket size and most of the orders were purchased with CoD (cash on delivery) option. While, CoD was essential for sustainable and profitable growth, it posed challenges for the business. In order to compete with the established players and, at the same time, be profitable, Desai examined the options that would help Onlymobiles.com create its niche in the market. He weighed between a change in the retail strategy or a change in the service strategy for Onlymobiles.com.
Design, Analysis, Fabrication, and Testing of a MEMS Flow Sensor (1999)

Abstract A new type of MEMS flow sensor has been designed, analyzed, fabricated, and tested. This sensor consists of a surface micromachined switch with a complex cantilever shape. A portion of the sensor is bent at a right angle to the substrate and to the flow direction. The fluid flow produces a pressure on the sensor; sufficient pressure causes the switch to close at the designed flow rate. These flow sensors have been developed for a large multi-university project for the design and construction of a biomimetic underwater lobster robot to be used to search for and destroy mines. However, we envision a variety of other uses for these flow sensors, including biomedical applications such as blood flow measurement. The fabrication process is based on the Northeastern University Metal Micromachining (NUMEM) technology [1]. The NUMEM process has been used to fabricate various surface micromachined metallic structures such as microrelays, microinterferometers, micromirrors, and microaccelerometers. The analysis of these devices consists of using incompressible fluid mechanics to determine the pressure acting on the sensor and beam theory to model the resulting deflection of the switch. The first set of flow sensors was designed to close at flow velocities of 0.5, 1.0, 3.4, and 5.4 m/s. The area of the paddle, which lies in the flow, is varied in order to obtain sensors that close at different flow rates. The results of testing agree well with the analytical predictions. Although these flow sensors are unidirectional, an array of four sensors at each point can be used to determine the flow velocity and direction.
THE EFFECT OF THYROXINE ANALOGUES ON A TRANSPLANTABLE MOUSE PITUITARY TUMOR1 (1960)

Journal Article THE EFFECT OF THYROXINE ANALOGUES ON A TRANSPLANTABLE MOUSE PITUITARY TUMOR Get access SOICHI KUMAOKA, SOICHI KUMAOKA 1The Sloan-Kettering Institute for Cancer Research of the Memorial Center New York, N. Y. Search for other works by this author on: Oxford Academic Google Scholar WILLIAM L. MONEY, WILLIAM L. MONEY 1The Sloan-Kettering Institute for Cancer Research of the Memorial Center New York, N. Y. Search for other works by this author on: Oxford Academic Google Scholar RULON W. RAWSON RULON W. RAWSON 1The Sloan-Kettering Institute for Cancer Research of the Memorial Center New York, N. Y. Search for other works by this author on: Oxford Academic Google Scholar Endocrinology, Volume 66, Issue 1, 1 January 1960, Pages 32–38, https://doi.org/10.1210/endo-66-1-32 Published: 01 January 1960 Article history Received: 02 June 1959 Published: 01 January 1960
Solid state photochemistry. Subpanel A-2(a): Design of molecular precursors for electronic materials (1996)

Recent achievements of synthetic chemistry in the field of electronic materials are presented in three categories; viz, precursor design for improved processing, new chemistry for selective growth, and new growth techniques. This is followed by a discussion of challenges and opportunities in two general areas designated as composition and structure, and growth and processing.
Analysis of the Chemical Distribution of Self-Assembled Microdomains with the Selective Localization of Amine-Functionalized Graphene Nanoplatelets by Optical Photothermal Infrared Microspectroscopy (2022)

By incorporating 1-(2-aminoethyl)piperazine (AEPIP) into a commercial epoxy blend, a bicontinuous microstructure is produced with the selective localization of amine-functionalized graphene nanoplatelets (A-GNPs). This cured blend underwent self-assembly, and the morphology and topology were observed <i>via</i> spectral imaging techniques. As the selective localization of nanofillers in thermoset blends is rarely achieved, and the mechanism remains largely unknown, the optical photothermal infrared (O-PTIR) spectroscopy technique was employed to identify the compositions of microdomains. The A-GNP tends to be located in the region containing higher concentrations of both secondary amine and secondary alcohol; additionally, the phase morphology was found to be influenced by the amine concentration. With the addition of AEPIP, the size of the graphene domains becomes smaller and secondary phase separation is detected within the graphene domain evidenced by the chemical contrast shown in the high-resolution chemical map. The corresponding chemical mapping clearly shows that this phenomenon was mainly induced by the chemical contrast in related regions. The findings reported here provide new insight into a complicated, self-assembled nanofiller domain formed in a multicomponent epoxy blend, demonstrating the potential of O-PTIR as a powerful and useful approach for assessing the mechanism of selectively locating nanofillers in the phase structure of complex thermoset systems.
Swirl-Based Control Method of Cell Orientation-Impact on Control Performance with Eccentricity (2014)

The adjustment of cell position and orientation is important in cell micromanipulation of bioengineering, which directly affects the efficiency and success ratio of the micromanipulation. Cell orientation can be adjusted by swirl, which comes from a pair of parallel opposite micro-fluids from two tiny tubes, and the cell in swirl center will rotate. Quantitative control of rotation angle and velocity of the cell can be achieved by adjusting the velocity and frequency of micro-fluid. This control method of cell orientation has prospective applications for its non-contact characteristics. However, cell will not be right in the swirl center in practical operations. And if the eccentric cell can rotate steadily, swirl method will be more reliable. So numerical simulation was conducted to study the movement trajectory of cells with eccentricity, and the influences of eccentric directions and eccentric distances were discussed. The simulation results indicate the feasibility of orientation control of cells with eccentricity by swirl.
An Explanation for the Asymmetry of the Modulation Sidebands about the Tooth Meshing Frequency in Epicyclic Gear Vibration (1985)

The vibration spectra of epicyclic gears commonly exhibit considerable asymmetry of the modulation sidebands and even complete suppression of the component at the tooth meshing frequency. A model is proposed which explains these observations in terms of the relationship between the vibrations generated by each of the planet gears as they move relative to the transducer location. Comparisons of the predictions of the model with measured vibration spectra for several epicyclic gearboxes show good agreement.
Investigating the role of cathepsin S in the pathogenesis of cystic fibrosis-like lung disease (2016)

Introduction: Elevated levels of the cysteine protease cathepsin S (cat S) are found in Cystic fibrosis (CF) lung secretions, however, the role of cat S in CF lung disease is unclear. Cat S is capable of maintaining its activity at a neutral pH allowing it to remain active outside of the cell. Consequently, cat S has the capacity to promote remodelling of the extracellular matrix via its potent elastolytic activity. In addition, cat S can cleave and inactivate key antimicrobials in the CF airways. On the basis of findings to date, we hypothesise that active cat S contributes to the pathogenesis of CF lung disease and represents a viable therapeutic target for the treatment of chronic lung disease.
Practitioner Review: Evidence‐based practice guidelines on alcohol and drug misuse among adolescents: a systematic review (2013)

There are a substantial number of guidelines addressing substance misuse in adolescents. However, only four high-quality guidelines included recommendations specific for adolescents. The current level of evidence that underpins the recommendations in these high-quality guidelines is low.
Control of single phase grid connected multilevel inverter using model predictive control (2013)

This paper presents a single phase seven-level inverter grid connected photovoltaic (PV) system application. The proposed system consists of a PV arrays, a single phase seven-level inverter interface and single phase power grid. The control of the inverter is based on a model predictive control algorithm where the main aim is to control the injected power which is produced by the PV source, to improve the quality of the current waveform, to reduce the THD of the current and to ensure the elimination of the shift phase between the injected current and the grid voltage in order to fulfill the requirement of the smart grid network. To clarify the advantages of the application of the model predictive control to the proposed topology, simulation results using MATLAB/SIMULINK and real time simulations using dSPACE 1103 are provided in this paper.
Leaders are made: Learning acquisition of consistent leader-follower relationships depends on implicit haptic interactions (2021)

ABSTRACT Are leaders made or born? Leader-follower roles have been well characterized in social science, but they remain somewhat obscure in sensory-motor coordination. Furthermore, it is unknown how and why leader-follower relationships are acquired, including innate versus acquired controversies. We developed a novel asymmetrical coordination task in which two participants (dyad) need to collaborate in transporting a simulated beam while maintaining its horizontal attitude. This experimental paradigm was implemented by twin robotic manipulanda, simulated beam dynamics, haptic interactions, and a projection screen. Clear leader-follower relationships were learned despite participants not being informed that they were interacting with each other, but only when strong haptic feedback was introduced. For the first time, we demonstrate the emergence of consistent leader-follower relationships in sensory-motor coordination, and further show that haptic interaction is essential for dyadic co-adaptation. These results provide insights into neural mechanisms responsible for the formation of leader-follower relationships in our society.
The role of ions and reaction sites for electrochemical reversible charge cycling in mesoporous nickel hydroxides (2013)

Layered nickel hydroxide thin films with mesoporous structure were prepared on ITO substrates by a facile chemical bath deposition method. The electrochemical properties of the nickel hydroxide/oxyhydroxide films were investigated in both potassium hydroxide and lithium perchlorate in propylene carbonate electrolytes. We show that the high reversible charge cycling capability of the material is enabled by the redox reaction involving hydroxyl ions, especially in the oxidative cycle. Li ion reversible charge cycling requires available reaction or adsorption sites that can be provided by sub-stoichiometry or defective films. Raising the defect concentration, the cyclic reversibility is shown to increase by ∼5 times. The effects of intercalated water in the interlayers are also discussed. We show that the presence of water in the interlayers can lead to a passivating reaction during the charge cycling and also cause optical efficiency losses through unwanted charge trapping.
Quick 3D Elemental Mapping of Biological Tissues using Super High Solid Angle EDS (2019)

Journal Article Quick 3D Elemental Mapping of Biological Tissues using Super High Solid Angle EDS Get access Yuuki Yamaguchi, Yuuki Yamaguchi JEOL Ltd. 3-1-2 Musashino, Akishima, Tokyo 196-8558 JAPAN Search for other works by this author on: Oxford Academic Google Scholar Hideo Nishioka, Hideo Nishioka JEOL Ltd. 3-1-2 Musashino, Akishima, Tokyo 196-8558 JAPAN Search for other works by this author on: Oxford Academic Google Scholar Yukari Moriya, Yukari Moriya JEOL Ltd. 3-1-2 Musashino, Akishima, Tokyo 196-8558 JAPAN Search for other works by this author on: Oxford Academic Google Scholar Chikako Nakayama, Chikako Nakayama JEOL Ltd. 3-1-2 Musashino, Akishima, Tokyo 196-8558 JAPAN Search for other works by this author on: Oxford Academic Google Scholar Tomohiro Haruta, Tomohiro Haruta JEOL Ltd. 3-1-2 Musashino, Akishima, Tokyo 196-8558 JAPAN Search for other works by this author on: Oxford Academic Google Scholar John Gilbert, John Gilbert Bruker Nano GmbH. Am Studio 2D, 12489 Berlin, GERMANY Search for other works by this author on: Oxford Academic Google Scholar Shunsuke Asahina Shunsuke Asahina JEOL Ltd. 3-1-2 Musashino, Akishima, Tokyo 196-8558 JAPAN Search for other works by this author on: Oxford Academic Google Scholar Microscopy and Microanalysis, Volume 25, Issue S2, 1 August 2019, Pages 1092–1093, https://doi.org/10.1017/S1431927619006196 Published: 01 August 2019
Assessing mesh convergence in discrete-fracture simulations that use random meshes (2014)

A pervasive fracturing process is one in which a multitude of cracks are dynamically active, propagating in arbitrary directions, coalescing, and branching. Pervasive fracturing is a highly nonlinear process involving complex material constitutive behavior, postpeak material softening, localization, new surface generation, and ubiquitous contact. A popular computational method for modeling pervasive fracture processes is to only allow fractures to propagate along interelement edges within a predefined finite-element mesh. With this approach, to avoid nonobjectivity in the simulation results, it is necessary to use a random mesh that has no preferred orientation. To define mesh convergence, simulation results are viewed in a weak or probabilistic sense rather than at the level of a single realization. For random variables, there are a number of different modes in which convergence may be understood. These are almost sure convergence, convergence in probability, and convergence in distribution. Each mode of convergence may be stronger or weaker than another. Herein, the fracture convergence assessment is based on demonstrating empirically the mode of convergence in distribution. Specifically, a sequence of cumulative distribution functions is verified to converge in the L∞ norm. The effect of finite sample sizes is quantified using confidence levels from the Kolmogorov–Smirnov statistic. This statistical method and convergence assessment is independent of the underlying distribution.
An inherent instability study using ab initio computational methods and experimental validation of Pb(SCN)2 based perovskites for solar cell applications (2020)

Perovskite materials with ABX<sub>3</sub> chemistries are promising candidates for photovoltaic applications, owing to their suitable optoelectronic properties. However, they are highly hydrophilic and unstable in nature, limiting the commercialization of perovskite photovoltaics. Mixed halide ion-doped perovskites are reported to be more stable compared to simple ABX<sub>3</sub> chemistries. This paper describes ab initio modeling, synthesis, and characterization of thiocyanate doped lead iodide CH<sub>3</sub>NH<sub>3</sub>PbI<sub>(3-x)</sub>(SCN)<sub>x</sub> perovskites. Several perovskite chemistries with an increasing concentration of (SCN)<sup>-</sup> at x = 0, 0.25, 0.49, 1.0, 1.45 were evaluated. Subsequently, 'n-i-p' and 'p-i-n' perovskite solar device architectures, corresponding to x = 0, 0.25, 0.49, 1.0 thiocyanate doped lead halide perovskite chemistry were fabricated. The study shows that among all the devices fabricated for different compositions of perovskites, p-i-n perovskite solar cell fabricated using CH<sub>3</sub>NH<sub>3</sub>PbI<sub>(3-x)</sub>(SCN)<sub>x</sub> perovskite at x = 1.0 exhibited the highest stability and device efficiency was retained until 450 h. Finally, a solar panel was fabricated and its stability was monitored.
Partial-Brain Radiation-Induced Microvascular Cognitive Impairment in Juvenile Murine Unilateral Hippocampal Synaptic Plasticity (2021)

PBRT induces a long-lasting impairment in neuroplasticity and the microvessel network of the irradiated hippocampus, whereas the contralateral hippocampus remains unaffected. These findings provide insight into the design of PBRT strategies to better protect the young developing brain from cognitive decline.
Lacey Baldwin Smith, Treason in Tudor England: Politics and Paranoia, Princeton: Princeton University Press, 1986. Pp. 342. $25.00 (ISBN: 0-691-05463-0). (1987)

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Data from Event-Free Survival as a Surrogate for Overall Survival in Gastric and Gastroesophageal Junction Adenocarcinoma: A Meta-analysis in the Neoadjuvant ± Adjuvant Setting (2023)

&lt;div&gt;AbstractPurpose:&lt;p&gt;This study assessed the trial-level association between event-free survival (EFS) and overall survival (OS) in gastric or gastroesophageal junction (GEJ) adenocarcinoma in the neoadjuvant ± adjuvant settings.&lt;/p&gt;Experimental Design:&lt;p&gt;A systematic literature review was conducted to identify randomized controlled trials (RCT) that evaluated neoadjuvant therapies with or without adjuvant therapies for gastric or GEJ adenocarcinoma. A meta-analysis was performed using weighted linear regressions of the treatment effect of OS on the treatment effect of EFS. The coefficient of determination (&lt;i&gt;R&lt;/i&gt;&lt;sup&gt;2&lt;/sup&gt;) and associated 95% confidence interval (CI) were used to evaluate the association between treatment effects of EFS and OS. The threshold used for defining good trial-level surrogacy was a correlation coefficient (&lt;i&gt;R&lt;/i&gt;) of 0.8 or &lt;i&gt;R&lt;/i&gt;&lt;sup&gt;2&lt;/sup&gt; of 0.65, based on prior literature. Sensitivity analyses were performed to assess the robustness of the association with divergent study designs, including study population, inclusion of adjuvant therapy, and definitions of EFS and OS.&lt;/p&gt;Results:&lt;p&gt;The main analysis included 16 comparisons from 15 RCTs. The log(HR) of EFS was a significant predictor of log(HR) of OS, with an estimated coefficient of 0.72 (&lt;i&gt;P&lt;/i&gt; &lt; 0.001) and &lt;i&gt;R&lt;/i&gt;&lt;sup&gt;2&lt;/sup&gt; = 0.75 (95% CI, 0.49–0.95), indicating that EFS was a good surrogate outcome for OS. The results of the sensitivity analyses were consistent with the primary results, with &lt;i&gt;R&lt;/i&gt;&lt;sup&gt;2&lt;/sup&gt; ranging from 0.76 to 0.89.&lt;/p&gt;Conclusions:&lt;p&gt;This study suggests that EFS is a good surrogate for OS in gastric or GEJ adenocarcinoma in the neoadjuvant ± adjuvant setting.&lt;/p&gt;&lt;/div&gt;
A novel mechanism of action of the fumagillin analog, TNP-470, in the B16F10 murine melanoma cell line (2005)

TNP-470, a semisynthetic derivative of fumagillin, is an acknowledged angiogenesis inhibitor, presently undergoing clinical trials. It exerts an anti-proliferative effect directed against endothelial cells. This effect is known to be based on cell cycle inhibition effected by the p53/p21 pathway. We observed short-term toxicity of TNP-470 in the B16F10 murine melanoma cell line in vitro and investigated the mechanism of action. Cell death occurred as soon as 2 h after the addition of TNP-470, without typical apoptotic features. The toxic effect could be modulated and it depended on the type of culture medium or supplementation with anti-oxidants. Addition of N-acetylcysteine protected B16F10 cells from TNP-470-induced death and inhibited an increase in the generation of reactive oxygen species (ROS), which are detected by the 2',7'-dichlorodihydrofluorescein diacetate probe. We conclude that TNP-470 can induce intracellular generation of ROS, which act toxically inside B16F10 cells. One may suggest that this novel activity of TNP-470 might be beneficial in some cases, but it could also be responsible for some undesirable side-effects. The possibility of its modulation gives a prospect for controlling the action of this potential drug and probably its derivatives.
A Magnetic Composite for Cleaning of Oil Spills on Water (2010)

Abstract The production of magnetic polymer composites for cleaning of oil spills on water is investigated. The polymer matrix consists of a biopolymer material (alkyd resin), which is cured with TDI in the presence of a magnetic powder (maghemite, γ ‐Fe 2 O 3 ), which is incorporated into the final polymer material in situ. Obtained polymer resins were characterized through magnetic force, AFM and WAXS/SAXS, showing that the proposed preparation technique leads to production of magnetic nanocomposites. Additionally, oil removal tests performed with polymer beads showed that the polymer product can be used to remove considerable amounts of oil from the surface of aqueous environments. In the best case, one part of the polymer product could be used to remove more than eight parts of oil from water. magnified image
Salt-in-Ionic-Liquid Electrolytes: Ion Network Formation and Negative Effective Charges of Alkali Metal Cations (2021)

Salt-in-ionic liquid electrolytes have attracted significant attention as potential electrolytes for next generation batteries largely due to their safety enhancements over typical organic electrolytes. However, recent experimental and computational studies have shown that under certain conditions alkali cations can migrate in electric fields as if they carried a net negative effective charge. In particular, alkali cations were observed to have negative transference numbers at small mole fractions of alkali metal salt that revert to the expected net positive transference numbers at large mole fractions. Simulations have provided some insights into these observations, where the formation of asymmetric ionic clusters, as well as a percolating ion network could largely explain the anomalous transport of alkali cations. However, a thermodynamic theory that captures such phenomena has not been developed, as ionic associations were typically treated via the formation of ion pairs. The theory presented herein, based on the classical polymer theories, describes thermoreversible associations between alkali cations and anions, where the formation of large, asymmetric ionic clusters and a percolating ionic network are a natural result of the theory. Furthermore, we present several general methods to calculate the effective charge of alkali cations in ionic liquids. We note that the negative effective charge is a robust prediction with respect to the parameters of the theory, and that the formation of a percolating ionic network leads to the restoration of net positive charges of the cations at large mole fractions of alkali metal salt. Overall, we find excellent qualitative agreement between our theory and molecular simulations in terms of ionic cluster statistics and the effective charges of the alkali cations.
Développement et validation d’un algorithme électronique d'évaluation de l'abondance des bulles en vidéocapsule endoscopique du grêle (2017)

Prix de la meilleure communication section endoscopie