gebhart/patrepeval huggingface dataset:
Expression pattern of glycoconjugates in the Bidderian and ovarian follicles of the Brazilian toad Bufo ictericus analyzed by lectin histochemistry (2006)

The Bidder's organ and ovary of the Brazilian toad Bufo ictericus were studied by light microscopy, using hematoxylin-eosin (HE) and periodic acid Schiff (PAS) staining. The expression and distribution of carbohydrate moieties was analyzed by lectin histochemistry, using 8 lectins with different carbohydrate specificities: Ulex europaeus (UEA I), Lens culinaris (LCA), Erythrina cristagalli (ECA), Arachis hypogaea (PNA), Ricinus communis (RCA I), Aleuria aurantia (AAA), Triticum vulgaris (WGA), and Glycine maximum (SBA). The results showed that the Bidderian zona pellucida presented alpha-mannose, alpha-L-fucose, beta-D-galactose, N-acetyl-D-glucosamine, and alpha/beta-N-acetyl-galactosamine residues. The Bidderian follicular cells showed the presence of beta-D-galactose and N-acetyl-D-glucosamine. In the extracellular matrix, alpha-mannose and alpha/beta-N-acetyl-galactosamine residues were detected. The ovarian zona pellucida showed alpha-L-fucose, N-acetyl-D-glucosamine, alpha/beta-N-acetyl-galactosamine residues, and alpha-mannose and N-acetyl-D-glucosamine residues were detected in the follicular cells. Thus, the zona pellucida in both organs contains N-acetyl-D-glucosamine, and alpha/beta-N-acetyl-galactosamine residues. alpha-L-fucose residues were detected in the zona pellucida of both organs, using different lectins. Considering that beta-D-galactose residue was absent from ovary but present in the Bidder's organ, this sugar residue may play an important role in follicle development, blocking the Bidderian follicles and preventing further development of the Bidder's organ into a functional ovary.
Ablation of Ventricular Tachycardia of Right Ventricular Origin with Low Energy Shocks (1989)

Three shocks of 2 joules (2,000 volts within 0.3 msec) were given to a patient with ventricular tachycardia of right ventricular origin at the site of the earliest activation. A standard 6 Fr USCI mapping catheter was used. After the first shock the cycle length prolonged from 385 to 531 msec. After the second shock, the tachycardia was no longer inducible and it remained so after 1 week. No recurrences were seen during a follow-up period of 8 months. This is the first report demonstrating efficacy of modified low energy shocks for ventricular tachycardia.
Detailed Performance Comparison of a Dump and Short Faired Combustor Diffuser System (1993)

A rectangular model simulating 4 sectors of a combustion chamber was used to compare the performance of a standard dump diffuser, of overall length 180mm, with that of a faired design 25.5mm shorter. The performance of each system was assessed in terms of total pressure loss and static pressure recovery between pre-diffuser inlet and the annuli surrounding the flame tube. Since the program objective was to test design concepts only, no allowance was made for the presence of burner feed arms or flame tube support pins. In addition, tests were performed with relatively low levels of inlet turbulence and no wake mixing effects from upstream compressor blades. Relative to the dump design, the mass weighted total pressure loss to the outer and inner annuli was reduced by 30% and 40% respectively for the faired diffuser. Measurements around the flame tube head were used to identify regions of high loss within each system and account for the differences in performance. Within a dump diffuser the flow separates at pre-diffuser exit resulting in a free surface diffusion around the flame tube head and a recirculating flow in the dump cavity. This source of loss is eliminated in the faired system where the flow remains attached to the inner casing. Furthermore, the faired system exhibited similar velocity magnitudes and gradients around the combustor head despite its shorter length.
ChemInform Abstract: Palladium‐Catalyzed Bispyrimidine Thioether Synthesis. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A Comparative Evaluation of Well-known Feature Detectors and Descriptors (2014)

Comparison of feature detectors and descriptors and assessing their performance is very important in computer vision. In this study, we evaluate the performance of seven combination of well-known detectors and descriptors which are SIFT with SIFT, SURF with SURF, MSER with SIFT, BRISK with FREAK, BRISK with BRISK, ORB with ORB and FAST with BRIEF. The popular Oxford dataset is used in test stage. To compare the performance of each combination objectively, the effects of JPEG compression, zoom and rotation, blur, viewpoint and illumination variation have investigated in terms of precision and recall values. Upon inspecting the obtained results, it is observed that the combination of ORB with ORB and MSER with SIFT can be preferable almost in all possible situations when the precision and recall results are considered. Moreover, the speed of FAST with BRIEF is superior to others.
REPLY (1988)

Adson, Martin H. M.D.; Anderson, Richard M.D.; Argenta, Louis C. M.D. Author Information
Opioid antagonists for alcohol dependence (2002)

Due to the limited evidence, the following conclusions should be viewed as tentative. NTX has some benefits for patients with alcohol dependence, but patients' adherence to treatment should be of concern. Psychosocial treatments should be concurrently given with NTX. The optimal duration of NTX treatment is not yet known. Although NTX is available for treating alcohol dependence in many countries, in the respect of cost-effectiveness, disulfiram should still remain as an alternative. Due to the dearth of evidence, at present, the combination of NTX and disulfiram or NMF alone should not be used in everyday clinical practice. Randomised, double-blind, placebo-controlled trials of NTX treatment in patients with alcohol dependence
Interaction of Cyclohexanediones with Acetyl Coenzyme-A Carboxylase and an Artificial Target-Site Antibody Mimic: A Comparative Molecular Field Analysis (2000)

Similarities and differences between steric and electrostatic potentials of a monoclonal-antibody-based surrogate of a herbicide target-site and its in vitro enzyme target were investigated using three-dimensional quantitative structure-activity relationship comparative molecular field analysis (3D-QSAR CoMFA). Two separate, five-component, partial least squares CoMFA models were developed to compare the interaction of cyclohexanedione herbicides with their target site, acetyl coenzyme-A carboxylase (ACCase; EC 6.4.1.2) and a cyclohexanedione pharmacophore-specific monoclonal antibody (mAb A). On the basis of CoMFA models, similarities in steric and electrostatic requirements around position 2 of the binding site for the oxime functional group of the cyclohexanedione molecule appear to be crucial for interaction of the herbicide with both ACCase and mAb A. These similarities explain the observed quantitative relationship between binding of cyclohexandedione herbicides to ACCase mAb A. Furthermore, these results support the production and use of mAb-based surrogates of pesticide targets as screening tools in pesticide discovery programs.
Why are My Flows Different? A Tutorial on Flow Exporters (2020)

Network flows build the basis of modern network data analysis by aggregating properties of network packets with common characteristics. A consistent and unambiguous definition of the network flow concept is an indispensable prerequisite and starting point for reproducible network research. However, in today's practice, the flow output of distinct flow exporters, which is software to generate flows from observed network packets, varies substantially on identical network packet stream input. In this paper we present an in-depth comparison of different flow exporters and show how their outputs differ significantly. We argue that this substantially impairs reproducibility for traffic analysis research. We first present the detailed flow definition of the IP Flow Information eXport (IPFIX) standard including explanations and examples, analyze design and implementation of existing flow exporters, and explore the reasons why many projects and publications chose to implement their own flow exporters. Based on this analysis we highlight the main challenges in the flow exporting process and present a detailed tutorial on how to design and implement a flow exporter such that it yields consistent, reproducible output. Based on the tutorial's theoretical analysis and lessons learned we present design and main concepts of a versatile, flexible, and open source flow exporting solution called go-flows that generates deterministic, reproducible network flows. Finally, we present a flow-by-flow comparison of the analyzed flow exporters' output, explore the differences in terms of their generated flows, compare flow exporter performance, and conclude with guidelines on parameters that play a crucial role in improving the reproducibility of exported flows.
Bactericidal efficacy of mupirocin in multi-antibiotic resistant Staphylococcus aureus born wound infection (1988)

Methicillin resistant Staphylococcus aureus strains (MRSA) have become increasingly prevalent as pathogenic organisms, especially in burn wounds, with an associated mortality of 20-40% among those clinically infected. Mupirocin ointment, a new topical antibiotic, has proved in vitro and in vivo to be highly effective in the treatment of MRSA infections. A modified Walker burn wound model was used to define the rate of trans-eschar penetration, biodynamic availability and bactericidal efficacy of 2% mupirocin ointment in established MRSA burn wound infection. In-vitro penetration trials confirmed the effective diffusion of mupirocin through 1.5 mm eschar within 2 h. A single topical application of mupirocin resulted in a 98.3% (5.67 x 10(8) cfu/g of tissue--1.0 x 10(7) cfu/g of tissue) reduction in intra-eschar viable organisms within 36 h post application. A second topical application of mupirocin at 24 h resulted in a total reduction of 99.6% in viable intra-eschar organisms (1.85 x 10(8) cfu/gram of tissue--6.76 x 10(5) cfu/g of tissue). It is concluded that mupirocin is highly effective in controlling MRSA burn wound infection and should be applied topically every 24 h.
Initial results from pilot plant evaluation of concentrated piperazine as a solvent for capturing co2 from a coal combustion flue gas (2012)

The CSIRO operates three CO2 capture pilot plants at coal fired power stations throughout Australia. The purpose of these pilot plants is to evaluate new technologies on real flue gases, with the aim of reducing the energy penalty and cost associated with CO2 capture. At the Tarong pilot plant operation has recently changed to using concentrated piperazine as a solvent. This promises to be an excellent alternative to the standard formulation based on monoethanolamine. From laboratory based research it can be inferred that piperazine is more reactive, has favourable regeneration energy requirements, and is thermally very stable. Previously piperazine has been restricted in CO2 capture applications to concentrations less than 10 wt% due to solubility issues. However, due to its attractive properties it has been used in commercially available solvents as a rate promoter (BASF aMDEA). Recent studies have highlighted that solubility issues can be avoided if the solvent is loaded with CO2. The Tarong pilot plant has been operating with piperazine since August 2011. In addition to plant performance, analysis of atmospheric emissions and solvent degradation products and by-products are also of concern. This paper presents preliminary results of operation of the pilot plant using concentrated piperazine, the additional health and safety aspects that must be considered, as well as monitoring of emissions from the pilot plant. These results will be used in the assessment of concentrated piperazine for post-combustion capture in Australian coal fired power plants.
Draft Genome Sequence of Actinomyces odontolyticus subsp. actinosynbacter Strain XH001, the Basibiont of an Oral TM7 Epibiont (2016)

Here, we present the draft genome sequence of Actinomyces odontolyticus subsp. actinosynbacter strain XH001, isolated from the human oral cavity. Uniquely, it was discovered as a host bacterium to the ultrasmall epibiont TM7x, which is the first cultivated member of "Candidatus Saccharibacteria" (formerly candidate phylum TM7).
Polymers for Fabricating Nerve Conduits (2010)

Peripheral nerve regeneration is a complicated and long-term medical challenge that requires suitable guides for bridging nerve injury gaps and restoring nerve functions. Many natural and synthetic polymers have been used to fabricate nerve conduits as well as luminal fillers for achieving desired nerve regenerative functions. It is important to understand the intrinsic properties of these polymers and techniques that have been used for fabricating nerve conduits. Previously extensive reviews have been focused on the biological functions and in vivo performance of polymeric nerve conduits. In this paper, we emphasize on the structures, thermal and mechanical properties of these naturally derived synthetic polymers, and their fabrication methods. These aspects are critical for the performance of fabricated nerve conduits. By learning from the existing candidates, we can advance the strategies for designing novel polymeric systems with better properties for nerve regeneration.
The Impact of Industry 4.0 Technologies on Manufacturing Strategies: Proposition of Technology-Integrated Selection (2022)

Industry 4.0 (I4.0) has increasingly been adopted as an advanced manufacturing strategy to counter global competition. The capability of a company to compete on various manufacturing strategy outputs (MSOs) such as cost, quality, delivery, flexibility, performance and innovativeness play a significant role in motivating the whole company to take advantage of its competitors. I4.0 is comprised of various technologies, and how I4.0 technologies can influence the MSOs are still unclear, and it took less interest in the literature. This article aims to analyze the influence of the I4.0 technologies on MSOs to achieve market competitiveness from the perspective of academic and industry experts. To do so, the influence of the adoption of various I4.0 technologies on the MSOs was investigated. Expert opinions were gathered on the relationship between manufacturing competitive capabilities and I4.0 technologies. The identification of the influential relationships provides arguments for the proposed I4.0 technology selections, which will allow companies to gain a highly competitive advantage. The results showed that the performance (regarding the MSOs) had a high potential for integration with different I4.0 technologies.
[Data processing for interferogram of ultraviolet Fourier transform spectrometer]. (2000)

The method of data processing for interferogram is described in this paper. The interferogram of a mercury lamp has been measured in experiment by means of ultraviolet Fourier Transform Spectrometer in developing. The apodization function that we have chosen is four-term Blackman-Harris window function and a fitting polynomial has been used for phase correction of Fourier Transform spectra based on the least square method. The ultraviolet emission lines of high precision have been obtained by use of this method.
A Spatiotemporal Method for the Monitoring of Image Data (2012)

Machine vision systems are increasingly being used in industrial applications because of their ability to quickly provide information on product geometry, surface defects, surface finish, and other product and process characteristics. Previous research for monitoring these visual characteristics using image data has focused on either detecting changes within an image or between images. Extending these methods to include both the spatial and the temporal aspects of image data would provide more detailed diagnostic information, which would be of great value to industrial practitioners. Therefore, in this article, we show how image data can be monitored using a spatiotemporal framework that is based on an extension of a generalized likelihood ratio control chart. The performance of the proposed method is evaluated through computer simulations and experimental studies. The results show that our proposed spatiotemporal method is capable of quickly detecting the emergence of a fault. The computer simulations also show that our proposed generalized likelihood ratio control charting method provides a good estimate of the change point and the size/location of the fault, which are important fault diagnostic metrics that are not typically provided in the image monitoring literature. Finally, we highlight some research opportunities and provide some advice to practitioners. Copyright © 2012 John Wiley &amp; Sons, Ltd.
647. lin-Poly-p-xylylene. Part I. Intermediates and polymers of low molecular weight (1953)

A. C. Farthing, J. Chem. Soc., 1953, 3261 DOI: 10.1039/JR9530003261
Expression of P2X7 ATP Receptor Mediating the IL8 and CCL20 Release in Human Periodontal Ligament Stem Cells (2013)

ATP is released by human periodontal ligament cells (hPDLCs) and has been shown to regulate PDL regeneration and responses to mechanical stress through activation of P2Y receptors. This nucleotide, however, has also been reported to trigger the pro-inflammatory cascade by inducing the maturation and/or release of chemokines/cytokines from various cell types mainly via P2X7 receptors. Much less is known on the possible role of ATP in stem cells deriving from PDL (hPDLSCs) which are considered to be a promising tool for cell-based therapy to restore lesions. Given the role played by P2X7 in pathophysiological conditions, in this study we investigated the expression of P2X7 ATP receptors in hPDLSCs. The results obtained showed that hPDLSCs express P2X7 receptors evaluated by means of cytofluorimetric, immunohistochemistry, reverse transcriptase-PCR, and Western blot analyses. P2X7 ligation by 2',3'-(benzoyl-4-benzoyl)-ATP (BzATP), a specific receptor agonist, was followed by an increase in intracellular Ca2+ and in the uptake of ethidium bromide. These effects were dramatically reduced by oxidized ATP (oATP), the P2X7 irreversible inhibitor, suggesting that the P2X7 is the functional receptor involved. At 24 h treatment of hPDLSCs with BzATP it enhanced the release of the pro-inflammatory agents IL8 and CCL20, without influencing cell viability. These effects were counteracted by pre-treating the cells with oATP or with A-740003, a selective and potent P2X7 competitive antagonist. Collectively, these results indicated that extracellular ATP mediate a pro-inflammatory response via P2X7 receptors in hPDLSCs opening a further approach to control hPDLSCs behavior in their possible application as therapeutic tool.
Anodic Oxidation of Cadmium and Reduction of Cadmium Hydroxide and Oxide in Alkaline Solutions (1966)

The anodic oxidation of smooth cadmium and the subsequent reduction of cadmium hydroxide and oxide were studied by voltammetric methods with and without superimposed a‐c voltage. Under voltammetric conditions a layer of appears to be formed at potentials below the passivation potential. Passivation results from a continuous thin film which forms at potentials between 0.05 and O.1v. The small capacitance and the large resistance of the interface electrode/solution are due to this film. On reduction the thin film is reduced first. A pseudocapacitance which is attributed to the adsorption of radicals is observed during the anodic sweep in a potential range where formation of or is not yet possible.
Long-Term Evaluation of the Fate of Sulfur Mustard on Dry and Humid Soils, Asphalt, and Concrete (2011)

The long-term fate of the blister agent sulfur mustard (HD, bis(2-chloroethyl)sulfide) was determined in a variety of commercial and natural matrices. HD was found to be extremely stable in dry matrices for over a year. The addition of 5% water to the matrices induced slow degradation of HD, which lasted several months. The major degradation product in sands and asphalt was found to be a sulfonium salt, S[CH(2)CH(2)S(+)(CH(2)CH(2)OH)(2)](2) (H-2TG). Red loam soil, which has not been examined before, exhibited strong interaction with HD, both in dry form and in the presence of water. Humid red loam soil gave rise to unique oxidative degradation products. On humid concrete HD degraded to a complex mixture of products, including vinyls. This may be attributed to the basic sites incorporated in concrete.
General Approach to Identifying Potential Targets for Cancer Imaging by Integrated Bioinformatics Analysis of Publicly Available Genomic Profiles (2011)

Molecular imaging has moved to the forefront of drug development and biomedical research. The identification of appropriate imaging targets has become the touchstone for the accurate diagnosis and prognosis of human cancer. Particularly, cell surface- or membrane-bound proteins are attractive imaging targets for their aberrant expression, easily accessible location, and unique biochemical functions in tumor cells. Previously, we published a literature mining of potential targets for our in-house enzyme-mediated cancer imaging and therapy technology. Here we present a simple and integrated bioinformatics analysis approach that assembles a public cancer microarray database with a pathway knowledge base for ascertaining and prioritizing upregulated genes encoding cell surface- or membrane-bound proteins, which could serve imaging targets. As examples, we obtained lists of potential hits for six common and lethal human tumors in the prostate, breast, lung, colon, ovary, and pancreas. As control tests, a number of well-known cancer imaging targets were detected and confirmed by our study. Further, by consulting gene-disease and protein-disease databases, we suggest a number of significantly upregulated genes as promising imaging targets, including cell surface-associated mucin-1, prostate-specific membrane antigen, hepsin, urokinase plasminogen activator receptor, and folate receptors. By integrating pathway analysis, we are able to organize and map "focused" interaction networks derived from significantly dysregulated entity pairs to reflect important cellular functions in disease processes. We provide herein an example of identifying a tumor cell growth and proliferation subnetwork for prostate cancer. This systematic mining approach can be broadly applied to identify imaging or therapeutic targets for other human diseases.