gebhart/patrepeval huggingface dataset:
Innovar para resolver problemas: el Design Thinking en la enseñanza del periodismo y la publicidad digital (2016)

espanolEnsenar y aprender a detectar necesidades de los publicos y ofrecer soluciones a sus problemas reales en un contexto de creatividad. Con este objetivo de partida se desarrollaron dos asignaturas complementarias, Planificacion y Desarrollo de Proyectos en la Red y Comunicacion Multimedia en los Grados universitarios de Periodismo, Periodismo y Comunicacion Audivisual y Publicidad y Relaciones Publicas ajustando su guia docente y su metodologia al cambiante entorno comunicativo en el contexto digital. La metodologia Design Thinking (base teorica y practica de todo el proceso) ofrece al profesorado y al alumnado un metodo claro y un esquema de trabajo que permite generar ideas innovadoras que derivan en proyectos de comunicacion digital. La innovacion enfocada asi contribuye a alinear las necesidades y experiencias del usuario con las caracteristicas del producto digital y la forma de producirlo. El pensamiento de diseno es una hoja de ruta adecuada tambien para preparar una entrevista, un reportaje, un documental o una campana publicitaria en el entorno digital. EnglishTeaching and learning to identify needs of publics and offer solutions to their real problems in a context of creativity. With this objective in starting two complementary subjects, Planning and Project Development in the Internet and Communication Multimedia developed in university Degrees of Journalism, Journalism and Communication Audiovisual and Advertising and Public Relations adjusting their teaching guide and methodology to the changing communication environment in the digital context. The Design Thinking (theoretical and practical basis of the whole process) methodology provides teachers and students a clear method and a roadmap that can generate innovative ideas that result in digital communication projects. Innovation focused thus helps to align the needs and user experiences with digital product features and how to produce it. Design thinking is a road route suitable also to prepare an interview, a documentary or an advertising campaign in the digital environment.
Coherent Receivers for Phase-Shift Keyed Transmission (2007)

We review coherent receiver implementations and their performance for phase-shift keyed transmission. Experimental results of a heterodyne receiver for 10 Gb/s DPSK are presented as well.
A molecular beacon, bead-based assay for the detection of nucleic acids by flow cytometry (2005)

Molecular beacons are dual-labelled probes that are typically used in real-time PCR assays, but have also been conjugated with solid matrices for use in microarrays or biosensors. We have developed a fluid array system using microsphere-conjugated molecular beacons and the flow cytometer for the specific, multiplexed detection of unlabelled nucleic acids in solution. For this array system, molecular beacons were conjugated with microspheres using a biotin-streptavidin linkage. A bridged conjugation method using streptavidin increased the signal-to-noise ratio, allowing for further discrimination of target quantitation. Using beads of different sizes and molecular beacons in two fluorophore colours, synthetic nucleic acid control sequences were specifically detected for three respiratory pathogens, including the SARS coronavirus in proof-of-concept experiments. Considering that routine flow cytometers are able to detect up to four fluorescent channels, this novel assay may allow for the specific multiplex detection of a nucleic acid panel in a single tube.
Outcomes of Early-Onset Acute Type A Aortic Dissection　― Influence of Etiologic Factors ― (2018)

Late aortic events are common in young ATAAD patients. Known etiologic factors, though not BAV, negatively influence late outcomes in these patients.
Some Structures and Properties of Very High Molecular Weight Linear Polyethylene (Special Issue on Polimar Chemistry, VI) (1968)

The orientational structures of crystalline and noncrystalline chains for a very high molecular weight linear polyethylene (Mv = 2.5 x 106), which was crystallized from the molten and stretched state maintaining the stretched length of the sample at constant, were investigated by birefringence and x-ray diffraction measurements.The stress-strain behavior at temperatures above the melting point, and the thermal shrinkage, the dynamic mechanical property and the melting behavior of the sample crystallized in such a way were also studied.This polymer could be stretched without breaking, behaving like rubbery materials at the molten state, as we have observed for a crosslinked polyethylene.The orientational structure of the crosslinked polyethylene, which was crystallized from a highly stretched and molten state, has been analyzed to be composed of highly oriented crystalline chains and little oriented noncrystalline chains.An analogous orientational structure to the above mentioned crosslinked polyethylene was again found for the present sample polymer, when it was prepared in the same way as taken for the crosslinked polyethylene.This characteristic structure of the sample was well reflected in the behavior of the thermal shrinkage, suggesting a very high thermal stability of crystals in the sample crystallized in such a way.This high thermal stability of the crystals was confirmed by determining the melting point and the temperature dependency of dynamic mechanical properties of the sample.
ChemInform Abstract: A 1,3‐DIPOLAR CYCLOADDITION OF ALICYCLIC METHYLENE IMINIUM YLIDE TO FORM PYRROLIZIDINE NUCLEI AND ITS APPLICATION TO SYNTHESIS OF PYRROLIZIDINE ALKALOIDS (1983)

Abstract Aus den Hexahydrotriazinen (I) bzw. (IX) bilden sich mit Trimethylsilylmethyltri?at (III) in Gegenwart von Cäsium‐fluorid Methyleniminiumylide, die mit elektronenarmen Olefinen (II), (V) oder Acetylendicarbonsäuredimethylester (VII) zu den im Formelschema aufgeführten Cycloaddukten reagieren.
Kinetics and mechanism of the oxidative dehydrogenation of n-butane over a SiO2-supported VMgO catalyst (2010)

An experimental study, and the corrresponding simulation, for the oxidative dehydrogenation of n-butane over a SiO2(30 wt%)-supported VMgO catalyst (with a Mg/V atomic ratio of 4 and a surface area, SBET, of 73 m2/g) is presented. Experimental data were obtained using a packed bed quartz tubular reactor operating under steady-state conditions, isothermal, and uniform flow conditions, varying the temperature within the range of 475-550°C, the contact time from 10 to 60 gcat/(moln-butane/h), the inlet molar fraction of n-butane from 2 to 8% and that of oxygen from 8 to 20%. The proposed model is based on a sound reaction scheme, with kinetics expression derived using the redox mechanism of Mars-Van Krevelen. The best fitting was obtained with a correlation coefficient of 0.8715 and a variance of 1.33 x10-3.
ChemInform Abstract: The Witkop—Winterfeldt Oxidation of Indoles (2008)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Using Data Mining Approaches for Force Prediction of a Dynamically Loaded Flexible Structure (2014)

This paper presents the results obtained from a research work investigating the performance of different Adaptive models developed to predict excitation forces on a dynamically loaded flexible structure. For this purpose, a flexible structure is equipped with acceleration transducers at each degree of freedom and a force transducer for validation and training. The models are trained using data obtained from applying a random excitation force on the flexible structure. The performance of the developed models is evaluated by analyzing the prediction capabilities based on a normalized prediction error. The frequency domain is considered to analyze the similarity of the frequencies in the predicted and the original force signal. For a selection of the best models, a more advanced performance analysis is carried out. This includes application of the trained models to deterministic and non-deterministic excitation forces with different excitation frequencies and amplitudes. Additionally, the influence of the sampling frequency and sensor location on the model performance is investigated. The results obtained in this paper show that most data mining approaches can be used, when a certain degree of inaccuracy is accepted. Furthermore, the comparison study points out that the transducer location is crucial for the model performance. However, there exists no general solution for the final selection of models.
P‐182: Long‐Life Green Phosphorescent OLED with Light‐Emitting Layer Formed by Two‐Source Evaporation Using Host Material with Novel Hetero Fused Ring (2019)

We developed an electron‐transport (ET) host material with a novel hetero fused ring which prolongs the lifetime of green phosphorescent organic light‐emitting diodes (OLEDs). We also developed a premixed host containing the ET host and a hole‐transport host. The use of the premixed host can facilitate production of the OLEDs.
Eta-Expansion Does The Trick (Revised Version) (1996)

&lt;p&gt;Partial-evaluation folklore has it that massaging one's source programs can make them specialize better. In Jones, Gomard, and Sestoft's recent textbook, a whole chapter is dedicated to listing such "binding-time improvements": nonstandard use of continuation passing style, eta-expansion, and a popular transformation called "The Trick". We provide a unified view of these binding-time improvements, from a typing perspective.&lt;br /&gt;Just as a proper treatment of product values in partial evaluation&lt;br /&gt;requires partially static values, a proper treatment of disjoint sums requires moving static contexts across dynamic case expressions. This requirement precisely accounts for the nonstandard use of continuation-passing style encountered in partial evaluation. Eta-expansion thus&lt;br /&gt;acts as a uniform binding-time coercion between values and contexts, be they of function type, product type, or disjoint-sum type. For the latter case, it enables "The Trick".&lt;br /&gt;In this article, we extend Gomard and Jones's partial evaluator&lt;br /&gt;for the lambda-calculus, lambda-Mix, with products and disjoint sums; we point&lt;br /&gt;out how eta-expansion for (finite) disjoint sums enables The Trick; we generalize our earlier work by identifying that eta-expansion can be obtained in the binding-time analysis simply by adding two coercion rules; and we specify and prove the correctness of our extension to lambda-Mix.&lt;/p&gt;&lt;p&gt;&lt;br /&gt;Keywords: Partial evaluation, binding-time analysis, program specialization,&lt;br /&gt;binding-time improvement, eta-expansion, static reduction.&lt;/p&gt;
Computer and measurement simulation of a new digital receiver operating directly at millimeter-wave frequencies (1995)

A novel digital millimetric receiver (DMR) scheme is introduced. Using a six-port phase/frequency discriminator (SPD) in conjunction with a digital signal processor (DSP), the receiver performs various PSK and QAM demodulations directly at microwave and millimeter-wave frequencies. An important feature of the new DMR is that hardware imperfections such as phase/amplitude imbalance are readily eliminated by a simple calibration procedure. The concept is proved through computer simulation and measurements at 26.5 GHz. This receiver scheme is proposed for small/medium capacity digital terminals typically found in various wireless communication networks.
Partial purification from macrophages of a phospholipase A/sub 2/ that hydrolyzes arachidonic acid from phosphatidylcholine (1987)

The first step in platelet-activating factor production and arachidonic acid release from stimulated inflammatory cells is thought to be the activation of a phospholipase A/sub 2/ (PLA/sub 2/). The mouse macrophage cell line, RAW 264, was found to contain PLA/sub 2/ activity that hydrolyzed /sup 3/H-arachidonic acid from sonicated dispersions of 1-0-alkyl-linked phosphatidylcholine (PC). The PLA/sub 2/ was cytosolic, required calcium, and exhibited a broad pH optimum between 6 and 10. When the hydrolysis of /sup 3/H-arachidonic acid from 1-palmitoyl- and 1-hexadecyl-linked PC (15 ..mu..M) was compared, slightly higher activity against 1-acyl-linked PC was found. However, the activity against 1-palmitoyl-linked PC substrates containing oleic or linoleic acids (sn-2) was considerably lower. To understand the properties of the PLA/sub 2/ in more detail, purification was undertaken. After ammonium sulfate precipitation the PLA/sub 2/ was fractionated over G150, on which it eluted slightly before an albumin marker. The enzyme bound to DEAE cellulose at pH 8.0 and was eluted in 0.3M NaCl. Further purification was achieved by hydrophobic chromatography over phenyl Sepharose followed by ion-exchange chromatography using Q-Sepharose resulting in 200-700-fold increases in specific activity. These results demonstrate the presence of a cytosolic PLA/sub 2/ in macrophages that shows specificity for arachidonicmore » acid at the sn-2 position of PC, has an apparent molecular weight greater than or equal to albumin, is anionic at pH 8.0 and is relatively hydrophobic.« less
ERA, a novel cis‐acting element required for autoregulation and ethanol repression of PDC1 transcription in Saccharomyces cerevisiae (1996)

Yeast pyruvate decarboxylase (Pdc) catalyses the reaction at the branch-point of fermentation and respiration. In this work we have investigated the mechanisms of its transcriptional regulation in response to glucose and the non-fermentable carbon source ethanol. For this purpose we studied the function of different promoter fragments of PDC1, encoding the major pyruvate decarboxylase enzyme in wild-type cells, in the basal CYC1 promoter context. Thus, we identified a sequence mediating the response to ethanol and provide evidence showing that transcription of PDC1 is controlled by ethanol repression rather than by glucose induction. Furthermore, we showed that the same sequence is responsible for an autoregulatory process, leading to increased transcription from both the PDC1 and the PDC5 promoters, in strains in which the genomic copy of PDC1 is deleted. In addition, we have confirmed the role of Rap1 binding and have demonstrated that the Gcr1 protein also acts in transcriptional activation. DNA-protein interactions at the consensus Rap1-binding site and the newly identified ethanol-repression sequence (5'-AAATGCATA-3', termed 'ERA') were investigated by gel-shift and footprint analyses. Both DNA-binding activities were found in extracts from cells grown in media containing glucose or ethanol as the carbon source, indicating that the capacity to bind is not altered by the carbon source used.
Multimodality Imaging-Based Characterization of Regional Material Properties in a Murine Model of Aortic Dissection (2020)

Chronic infusion of angiotensin-II in atheroprone (ApoE<sup>-/-</sup>) mice provides a reproducible model of dissection in the suprarenal abdominal aorta, often with a false lumen and intramural thrombus that thickens the wall. Such lesions exhibit complex morphologies, with different regions characterized by localized changes in wall composition, microstructure, and properties. We sought to quantify the multiaxial mechanical properties of murine dissecting aneurysm samples by combining in vitro extension-distension data with full-field multimodality measurements of wall strain and thickness to inform an inverse material characterization using the virtual fields method. A key advance is the use of a digital volume correlation approach that allows for characterization of properties not only along and around the lesion, but also across its wall. Specifically, deformations are measured at the adventitial surface by tracking motions of a speckle pattern using a custom panoramic digital image correlation technique while deformations throughout the wall and thrombus are inferred from optical coherence tomography. These measurements are registered and combined in 3D to reconstruct the reference geometry and compute the 3D finite strain fields in response to pressurization. Results reveal dramatic regional variations in material stiffness and strain energy, which reflect local changes in constituent area fractions obtained from histology but emphasize the complexity of lesion morphology and damage within the dissected wall. This is the first point-wise biomechanical characterization of such complex, heterogeneous arterial segments. Because matrix remodeling is critical to the formation and growth of these lesions, we submit that quantification of regional material properties will increase the understanding of pathological mechanical mechanisms underlying aortic dissection.
Design of a Q-Band High Efficiency Helix TWT (2023)

A Q-band high efficiency helix traveling wave tube (TWT) is designed and simulated in this paper. By using appropriate slow wave structure and taking reasonable helix pitch tapering method, high electronic efficiency and output power can be obtained. The 3D electromagnetic simulation software CST is used for the calculation of the high frequency characteristics and beam-wave interaction. The preliminary simulation results show that no oscillation is observed in the output signal. The electronic efficiency of this helix TWT exceeds 25.8% within the frequency range of 37-42.5GHz, the output power is more than 220W, and the gain is greater than 51dB.
Abstract PR-008: Identification and characterization of the molecular mechanisms of SCLC chemo-radiation resistance (2021)

Abstract Small cell lung cancer (SCLC) is among the most aggressive form of lung malignancies and accounts for 15-20% of all lung cancers. It has the tendency to metastasize early, thus limited-stage SCLC patients still receive systemic treatment with chemo-radiotherapy (chemoXRT) for their localized disease. SCLC is exceptionally sensitive to chemoXRT and exhibits high response rates; however, the recurrence rate is almost 100% and patients relapse with tumors that resist further treatments. Elucidating mechanisms of chemoXRT resistance in SCLC is needed to develop improved therapies and positively impact patient outcomes. To better interrogate mechanisms of chemoXRT resistance, we developed a SCLC patient-derived xenograft (PDX) in vivo system for the major molecular subtypes of SCLC (classic and variant). Briefly, PDX tumor bearing mice were treated with: 1) vehicle control; 2) cisplatin plus etoposide (EP); 3) radiotherapy (XRT); and 4) both EP/XRT. A major response was observed within the EP/XRT arm compared to vehicle or single therapy arms. Whole transcriptome profiling among all treatment arms revealed molecular pathways and biological processes associated with chemoXRT resistance. Also, by comparing our data with two previous SCLC patient cohort studies, we identified gene candidates for functional validation of chemoXRT resistance (i.e. ST6GAL1, TNIK and SOHLH2). To enable real-time cellular and molecular analysis of PDX behavior ex vivo and to validate SCLC chemoXRT resistance candidate genes, we established a novel PDX organoid (PDO) model to study the molecular underpinnings of XRT resistance in SCLC. Classic and variant SCLC PDOs still retained the cellular, DNA and RNA markers consistent with their parental PDX molecular subtype classification using array comparative genomic hybridization and RNA-sequencing. We aim to utilize our novel SCLC PDX/PDO models as a tool to identify and validate candidates for chemoXRT resistance to be used as biomarkers and targets to combat chemoXRT resistance in SCLC. Citation Format: Francesca Anna Carrieri, Nick Connis, Eloise Grasset, Eddie Luidy-Imada, Andrew Ewald, Luigi Marchionni, Christine Hann, Phuoc T. Tran. Identification and characterization of the molecular mechanisms of SCLC chemo-radiation resistance [abstract]. In: Proceedings of the AACR Virtual Special Conference on Radiation Science and Medicine; 2021 Mar 2-3. Philadelphia (PA): AACR; Clin Cancer Res 2021;27(8_Suppl):Abstract nr PR-008.
Topical flurbiprofen treatment of periodontitis in beagles (1988)

The effect of the non‐steroidal anti‐inflammatory drug flurbiprofen, topically applied, on the progression of periodontal disease was studied in 12 beagle dogs over a 13‐month period. Standardized radiographs were used to measure the rate of bone loss. Following a 6‐month pretreatment baseline period, 6 dogs were treated daily with 0.3 mg flurbiprofen gently applied to the gingival margin in 1 ml of gel vehicle. Six untreated dogs served as controls. In the untreated control dogs the rate of bone loss in the treatment period did not change significantly from baseline, although the rate was elevated by 38%. In contrast, the rate of bone loss significantly decreased by 71% from baseline in the flurbiprofen‐treated dogs. The untreated control dogs lost 10 teeth during the treatment period whereas the topical flurbiprofen‐treated dogs lost only 1 tooth. The data indicate that topical application of flurbiprofen in a gel vehicle significantly inhibits alveolar bone loss in beagles over a 7‐month treatment period. The data also indicate that topical flurbiprofen is associated with the loss of considerably less teeth than in untreated control dogs over the 7‐month treatment period.
Optimal power allocation based on sum-throughput maximization for energy harvesting cognitive radio networks (2017)

An experimental
Artificial Intelligence in Accounting (2020)

Artificial Intelligence in Accounting: Practical Applications was written with a simple goal: to provide accountants with a foundational understanding of AI and its many business and accounting applications. It is meant to serve as a guide for identifying opportunities to implement AI initiatives to increase productivity and profitability. This book will help you answer questions about what AI is and how it is used in the accounting profession today. Offering practical guidance that you can leverage for your organization, this book provides an overview of essential AI concepts and technologies that accountants should know, such as machine learning, deep learning, and natural language processing. It also describes accounting-specific applications of robotic process automation and text mining. Illustrated with case studies and interviews with representatives from global professional services firms, this concise volume makes a significant contribution to examining the intersection of AI and the accounting profession. This innovative book also explores the challenges and ethical considerations of AI. It will be of great interest to accounting practitioners, researchers, educators, and students.
Endoskopischer Vakuum-assistierter Verschluss (VAC) bei Anastomoseninsuffizienzen nach anteriorer Rektumresektion (2010)

Einleitung: Die konservative Therapie einer Anastomoseninsuffizienz nach anteriorer Rektumresektion ist eine Therapiemöglichkeit bei Patienten ohne generalisierte Peritonitis. Diese Untersuchung beschreibt das endoskopische Vorgehen zur Behandlung von Anastomoseninsuffizienzen bei diesen Patienten durch einen Vakuum-assistierten Verschluss.
Fabry disease in a heterozygote presenting as hand ischaemia and painful acroparaesthesia (2007)

A 48-year-old woman presented with acute unilateral ischaemia of the left hand. She had a background of chronic peripheral neuropathic pain, palpitations, anaemia and an episode of superficial thrombophlebitis. Physical examination revealed non-blanching purple discoloration of her left fingers and her left thumb, index finger and thenar eminance appeared ischaemic. Digital subtraction angiography of the left hand demonstrated reduced flow. Skin punch biopsy histology was unremarkable. The diagnosis of Fabry disease was made on urine lipid profile analysis and confirmed by reduced peripheral blood leukocyte alpha-galactosidase A activity.