gebhart/patrepeval huggingface dataset:
Mechanical characteristic of steel fibre concrete arc shaft wall structure (2010)

Aiming at the difficult problem of reinforcement for coal mine shafts in the deep alluvium,steel fibre concrete arc shaft wall applied to outer shaft wall of freezing shaft was proposed.Mechanical characteristic of the shaft wall structure was analyzed by model test.The results indicate that steel fibre can enhance toughness of arc shaft wall,and circumferential peak strain of steel fibre concrete amount to 2 200～2 300 μe before shaft wall is damaged.Steel fibre can also improve deformation character of the shaft wall,and the most radial displacement of shaft wall amount to more than 20 mm when it is damaged.Making use of finite element model which was validated by model test,bearing capacity influencing factor of arc shaft wall was analyzed,and the result indicates that compressive strength of concrete and thickness-diameter ratio are main factor,and that steel fibre content has less effect on bearing capacity.In the end,bearing capacity empirical formula of steel fibre arc shaft wall was gained.
DICHLOROACETATE REDUCES ARTERIAL LACTATE IN PATIENTS WITH LOW CARDIAC OUTPUT SYNDROME FOLLOWING CARDIAC SURGERY (1998)

ANESTHESIOLOGY is the highest-impact, peer-reviewed medical journal that publishes trusted evidence that transforms the practice of perioperative, critical care, and pain medicine along with clinical reviews, editorials, podcasts, infographics, and videos.
Endorectal Mucosal Resection Without Proctectomy as an Adjunct to Abdominoperineal Resection for Nonmalignant Conditions (1978)

Five patients with chronic ulcerative colitis underwent endorectal excision of the rectal mucosa without removing the rectal muscle in combination with total colectomy and cutaneous ileostomy. This operative technique will cure the patient of the primary disease and obviates many of the usual unpleasant complications following total proctectomy, such as prolonged perineal drainage and sexual and bladder dysfunction. It has the further advantages of lower operative blood loss and earlier safe ambulation. On the basis of favorable clinical experience with these patients, we believe that the operation warrants further clinical trial in patients who have biopsy-proven ulcerative colitis without severe rectal ulcerations as well as in certain other nonmalignant conditions originating in the rectal mucosa.
Classification of tumors and masses in mammograms using neural networks with shape and texture features (2004)

We propose an approach using artificial neural networks to classify masses in mammograms as malignant or benign. Single-layer and multi-layer perceptron networks were used in a study on perceptron topologies for pattern classification of breast masses. The boundaries of 108 breast masses and tumors were manually delineated and represented by polygonal models for shape analysis. Ribbons of pixels were extracted around the boundary of each mass. Three shape factor measures based on the contours, and fourteen texture features based on gray-level co-occurrence matrices of the pixels in the ribbons were computed. Various combinations of the features were used with perceptrons of several topologies for classification of benign masses and malignant tumors. The results were compared in terms of the area A/sub Z/ under the receiver operating characteristics curve. Values of A/sub Z/ up to 0.99 were obtained with the shape factors, whereas texture features provided A/sub z/ up to only 0.63.
Bystander Cell Death is Modified by Sites of Energy Deposition within Cells Irradiated with a Synchrotron X-Ray Microbeam (2010)

Radiation-induced bystander effects are the biological responses exhibited by cells adjacent to cells that have been traversed by charged particles. Using a synchrotron X-ray microbeam irradiation system, we irradiated five cells in two different ways: by targeting the nuclei with 10 microm x 10-microm 5.35 keV X-ray beams and by irradiating the whole cells with 50 microm x 50-microm 5.35 keV X-ray beams. Then we measured the clonogenic survival of the bystander cells. When only the nuclei were irradiated, a parabolic enhancement of bystander cell death was observed in a dose-dependent manner in the low-dose region around 1 Gy. In contrast, the surviving fraction of bystander cells decreased monotonically when whole cells were irradiated. Addition of carboxy-PTIO, a specific scavenger of nitric oxide (NO), suppressed bystander cell death in both cases. These results indicate that NO is a mediator in the induction of the parabolic and monotonic types of bystander cell death. Moreover, from the spatial analysis, we found that the parabolic type of bystander cell death was induced primarily within 1 mm of irradiated cells. Our findings demonstrate that the induction of bystander cell death depends on the sites of energy deposition in irradiated cells.
Le délit d'homophobie ou la violation de la Constitution par consensus (2005)

Tribune
<title>Distortion-invariant FOPEN detection filter improvements</title> (1999)

Various new improvements to the MINACE distortion-invariant filter are considered. Detection (P<SUB>D</SUB>) and false alarms (P<SUB>FA</SUB>) improvements obtained are noted. P<SUB>D</SUB> improved by approximately equals 25%. Initial ROC data and algorithm fusion results indicate that these new filters can improve the performance obtained by other methods.
Combustion and structure formation in SHS processes under microgravity conditions: SHS plans for microgravity experiments (1995)

This paper outlines ISMAN suggestions for the joint NASA-RSA project 'Combustion and Structure formation in SHS Processes under Microgravity Conditions'. The basic ideas of this work naturally follow from our almost 30-year experience in the field of SHS. As a matter of fact, we have already obtained some results in the following two directions closely related to the microgravity problem. One is the studies on SHS processes in the field of centrifugal forces. These studies aimed at the intensification of gravity-sensitive SHS processes in multicomponent highly caloric systems forming melts at high overloads (up to 2000 g). In other words, these studies had the objectives that are inverse to those in the microgravity studies. The second group of results directly relates to the microgravity problem and the project under consideration. These experiments played the important role in establishing links between SHS and microgravity.
Using Hansen solubility parameters to study the encapsulation of caffeine in MOFs (2014)

Hansen solubility parameters (HSP) have found their greatest use in the evaluation of solvent-polymer chemical interactions. Given their great interest among the scientific community, host-guest interactions in metal-organic frameworks (MOFs), with organic and inorganic moieties, could benefit from a HSP approach. In this work we have initiated the application of HSP to the study of caffeine encapsulation in MOFs ZIF-8 and NH2-MIL-88B(Fe). However, the availability of HSP for MOFs is nearly zero. As a first step to evaluating the potential of HSP for rational design we have made the simplifying assumption that the HSP distance of the caffeine-ligand interaction (i.e. ignoring the metal and the MOF structure) dominates the ability to form a MOF host-guest system. Although much work remains to be done, the first indications are that this approach has much potential.
A clustering analysis of eosinophilic asthmatics: Two clusters with sharp differences in atopic status and disease severity (2023)

The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.
Driving control system for an autonomous vehicle using multiple observed point information (2003)

A driving control system has been developed in which the weighting given to lane marker (white line) information obtained at multiple observed points ahead of the vehicle is varied according to the driving knowledge, global driving commands and data on the white line shapes. This driving knowledge stored in the memory includes driving behavior expressed in a form of rules, which make it possible to achieve the actual driving operations performed by human drivers. As a result, smooth, stable steering control can be obtained on various types of curved roads having a continuously varying radius of curvature and width. Tests of this driving control system indicate that it provides driving performance on a par with that of skilled drivers.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
A Low-Complexity Lattice-Based Low-PAR Transmission Scheme for DSL Channels (2004)

This paper presents a new low-complexity multicarrier modulation (MCM) technique based on lattices which achieves a peak-to-average power ratio (PAR) as low as three. The scheme can be viewed as a "drop in" replacement for the discrete multitone (DMT) modulation of an asymmetric digital subscriber line modem. We show that the lattice-MCM retains many of the attractive features of sinusoidal-MCM, and does so with lower implementation complexity, O(N), compared with DMT, which requires O(NlogN) operations. We also present techniques for narrowband interference rejection and power profiling. Simulation studies confirm that performance of the lattice-MCM is superior, even compared with recent techniques for PAR reduction in DMT.
Research roundup: July 2015 (2015)

In this section, a range of brief synopses of articles that may be of interest to health visitors is presented. The aim is to provide an overview of the papers selected. Should you wish to look at any of the papers in more detail, a full reference is provided.
The transaction concept: virtues and limitations (invited paper) (1981)

A transaction is a transformation of state which has the properties of atomicity (all or nothing), durability (effects survive failures) and consistency (a correct transformation). The transaction concept is key to the structuring of data management applications. The concept seems to have applicability to programming systems in general. This paper restates the transaction concepts and attempts to put several implementation approaches in perspective. It then describes some areas which require further study: (1) the integration of the transaction concept with the notion of abstract data type, (2) some techniques to allow transactions to be composed of sub-transactions, and (3) handling transactions which last for extremely long times (days or months).
Practical Parameters for Somewhat Homomorphic Encryption (SHE) Schemes on Binary Circuits (2018)

Post-quantum cryptography gets increasing attention lately, as we have to prepare alternative cryptographic solutions that will resist attacks from quantum computers. A very large effort is being done to replace the usual primitives such as encryption, signature or authentication. This effort also pulls new cryptographic features such as Somewhat or Fully Homomorphic Encryption schemes, based on lattices. Since their introduction in 2009, lots of the burden has been overcome and real applications now become possible. However many papers suffer from the fast constant pace of evolution on the attack side, so their parameter analysis is usually incomplete or obsolete. In this work we present a thorough study of two schemes that have proven their worth: FV and SHIELD, providing a deep analysis of how to setup and size their parameters, to ensure both correctness and security. Our overall aim is to provide easy-to-use guidelines for implementation purposes.
Roles for C-X-C chemokines and C5a in lung injury after hindlimb ischemia-reperfusion (1999)

We evaluated the roles of the C-X-C chemokines cytokine-induced neutrophil chemoattractant (CINC) and macrophage inflammatory protein-2 (MIP-2) as well as the complement activation product C5a in development of lung injury after hindlimb ischemia-reperfusion in rats. During reperfusion, CD11b and CD18, but not CD11a, were upregulated on neutrophils [bronchoalveolar lavage (BAL) and blood] and lung macrophages. BAL levels of CINC and MIP-2 were increased during the ischemic and reperfusion periods. Treatment with either anti-CINC or anti-MIP-2 IgG significantly reduced lung vascular permeability and decreased lung myeloperoxidase content by 93 and 68%, respectively (P < 0.05). During the same period, there were significant increases in serum C5a-related neutrophil chemotactic activity. Treatment with anti-C5a decreased lung vascular permeability, lung myeloperoxidase, and BAL CINC by 51, 58, and 23%, respectively (P < 0.05). The data suggest that the C-X-C chemokines CINC and MIP-2 as well as the complement activation product C5a are required for lung neutrophil recruitment and full induction of lung injury after hindlimb ischemia-reperfusion in rats.
Crohn's disease shared decision making intervention leads to more patients choosing combination therapy: a cluster randomised controlled trial (2022)

Evaluating a Shared Decision Making Program for Crohn's Disease, ClinicalTrials.gov Identifier NCT02084290 https://clinicaltrials.gov/ct2/show/NCT02084290.
Approaching the Kinetic Inertness of Macrocyclic Gadolinium(III)‐Based MRI Contrast Agents with Highly Rigid Open‐Chain Derivatives (2015)

A highly rigid open-chain octadentate ligand (H4 cddadpa) containing a diaminocylohexane unit to replace the ethylenediamine bridge of 6,6'-[(ethane-1,2 diylbis{(carboxymethyl)azanediyl})bis(methylene)]dipicolinic acid (H4 octapa) was synthesized. This structural modification improves the thermodynamic stability of the Gd(3+) complex slightly (log KGdL =20.68 vs. 20.23 for [Gd(octapa)](-) ) while other MRI-relevant parameters remain unaffected (one coordinated water molecule; relaxivity r1 =5.73 mm(-1) s(-1) at 20 MHz and 295 K). Kinetic inertness is improved by the rigidifying effect of the diaminocylohexane unit in the ligand skeleton (half-life of dissociation for physiological conditions is 6 orders of magnitude higher for [Gd(cddadpa)](-) (t1/2 =1.49×10(5) h) than for [Gd(octapa)](-) . The kinetic inertness of this novel chelate is superior by 2-3 orders of magnitude compared to non-macrocyclic MRI contrast agents approved for clinical use.
Automated non-rigid registration and mosaicing for robust imaging of distinct retinal capillary beds using speckle variance optical coherence tomography (2013)

Variance processing methods in Fourier domain optical coherence tomography (FD-OCT) have enabled depth-resolved visualization of the capillary beds in the retina due to the development of imaging systems capable of acquiring A-scan data in the 100 kHz regime. However, acquisition of volumetric variance data sets still requires several seconds of acquisition time, even with high speed systems. Movement of the subject during this time span is sufficient to corrupt visualization of the vasculature. We demonstrate a method to eliminate motion artifacts in speckle variance FD-OCT images of the retinal vasculature by creating a composite image from multiple volumes of data acquired sequentially. Slight changes in the orientation of the subject's eye relative to the optical system between acquired volumes may result in non-rigid warping of the image. Thus, we use a B-spline based free form deformation method to automatically register variance images from multiple volumes to obtain a motion-free composite image of the retinal vessels. We extend this technique to automatically mosaic individual vascular images into a widefield image of the retinal vasculature.
Helicobacter pylori cagA and vacA genotypes in Cuban and Venezuelan populations (2010)

The aim of this study was to determine the presence of Helicobacter pylori cytotoxin-associated gene (cagA)/vacuolating cytotoxin gene (vacA) among patients with chronic gastritis in Cuba and Venezuela. Gastric antrum biopsies were taken for culture, DNA extraction and PCR analysis. Amplification of vacA and cagA segments was performed using two regions of cagA: 349 bp were amplified with the F1/B1 primers and the remaining 335 bp were amplified with the B7629/B7628 primers. The VA1-F/VA1-R set of primers was used to amplify the 259-bp (s1) or 286-bp (s2) product and the VAG-R/VAG-F set of primers was used to amplify the 567-bp (m1) or 642-bp (m2) regions of vacA. cagA was detected in 87% of the antral samples from Cuban patients and 80.3% of those from Venezuelan patients. All possible combinations of vacA regions were found, with the exception of s2/m1. The predominant combination found in both countries was s1/m1. The percentage of cagA+ strains was increased by the use of a second set of primers and a greater number of strains was amplified with the B7629/B7628 primers in the Cuban patients (p = 0.0001). There was no significant difference between the presence of the allelic variants of vacA and cagA in both populations. The predominant genotype was cagA+/s1m1 in both countries. The results support the necessary investigation of isolates circulating among the human population in each region.
Quantifying the Topology of Magnetic Skyrmions in three Dimensions (2023)

Magnetic skyrmions have so far been treated as two-dimensional spin structures characterized by a topological winding number describing the rotation of spins across the skyrmion. However, in real systems with a finite thickness of the material being larger than the magnetic exchange length, the skyrmion spin texture extends into the third dimension and cannot be assumed as homogeneous. Using soft x-ray laminography we reconstruct with about 20nm spatial (voxel) resolution the full three-dimensional spin texture of a skyrmion in an 800 nm diameter and 95 nm thin disk patterned into a trilayer [Ir/Co/Pt] thin film structure. A quantitative analysis finds that the evolution of the radial profile of the topological skyrmion number and the chirality is non-uniform across the thickness of the disk. Estimates of local micromagnetic energy densities suggest that the changes in topological profile are related to non-uniform competing energetic interactions. Theoretical calculations and micromagnetic simulations are consistent with the experimental findings. Our results provide the foundation for nanoscale magnetic metrology for future tailored spintronics devices using topology as a design parameter, and have the potential to reverse-engineer a spin Hamiltonian from macroscopic data, tying theory more closely to experiment.
Crystal structure of NK2-heparin complex (2011)

Alpha-L-iduronidase (IDUA, EC: 3.2.1.76) is a lysosomal enzyme that cleaves terminal -iduronic acid residues from glycosaminoglycan, heparin sulphate, and dermatan sulphate. The deficiency of this enzyme causes Mucopolysaccharidosis Type I (MPS I) disease, also known as Hurler/Scheie syndrome. MPS I disease is appeared in child age and characterized by progressive mental retardation, gross facial features, enlarged and deformed skull, small stature, corneal opacities, hepatosplenomegaly, valvular heart defects, thick skin, joint contractures, and hernias. The treatment of MPS I is now mainly by an enzyme replacement therapies which introduce the recombinant IDUA to the blood by intravenous infusion. To date, many mutations of IDUA found in MPS I patients have been reported, however, details of relationship between the mutations and MPS I disease is poor. To elucidate the structural basis of MPS I and structure-based drug development, we have crystallized and determined the crystal structure of human IDUA at 2.5 resolution by SIRAS phasing. The crystal of human IDUA belongs to R3 spacegroup with its unit cell parameters as a=259.22 , b=259.22 , c=71.8 , and we have refined the model to Rwork=17.3%, Rfree=22.6%. The structural model includes almost the whole length of the polypeptide chain (27-642) and four oligosaccharide chains. The overall structure of IDUA is almost the same topology as XynB, which belongs to the same family in CAZy database (GH39). We could clearly observe a high-mannose chain, covalently attached at Asn372, is prolonged toward to the catalytic site. So, this oligosaccharide chain is suggested to be important for the enzymatic activities. The linkages of the mutation and phenotype of disease are discussed.
Effect of the Perioex® Fil Ter on Peritonitis Rates in an Unselecteo CAPO Population (1984)

The use of the inline filter in a CAPD population was associated with a low incidence of peritonitis (0.064 infections per patient month). Pre-filter rates of peritonitis indicated that the population was in general a group of “high risk” patients for peritonitis.
Abstract 19183: Insulin Resistance Develops after the Onset of Heart Failure in Dogs (2012)

Background: Heart failure (HF) is a condition associated with increased plasma norepinephrine levels. Norepinephrine is known to affect glucose homeostasis by decreasing insulin sensitivity. We have previously reported an increase in plasma norepinephrine levels in coronary microembolization-induced HF dogs. However, the status of plasma insulin and glucose levels is unknown in large animal models of HF. In the present study, we examined insulin and glucose levels in fasted plasma from dogs before and after the onset of HF. Methods: 12 healthy mongrel dogs weighing 20-30 kg underwent serial coronary microembolization to produce HF. Embolization was performed every 1-2 weeks until angiographic left ventricular ejection fraction (LVEF) was &lt;35%. All procedures were performed during cardiac catheterization, under general anesthesia and sterile conditions. Fasted plasma was collected before and after inducing HF and was stored at -80 o C. Insulin and glucose levels were determined using commercially available ELISA kits for insulin and colorimetric assay kits for glucose, and expressed in microunits/mL and mg/dL, respectively. Homeostasis assessment model for insulin resistance (HOMA-IR) ([fasting insulin in microunits/mL * fasting glucose in mg/dL] * 0.5551/22.5) was calculated in all dogs at baseline and after inducing HF. Data were analyzed using paired t-tests. Results: Baseline LVEF was &gt; 55% in all dogs. Once HF was established, mean LVEF was 31 ± 1%. Baseline mean fasting blood glucose and fasting plasma insulin were 84 ± 17 mg/dL and 9.7 ± 3.6 microunits/mL, respectively. Once HF was established, fasting blood glucose rose to 161 ± 44 mg/dL (p&lt;0.0001) and fasting plasma insulin increased to 16.5 ± 4.0 microunits/mL (p=0.0008). HOMA-IR score increased from 2.0 ± 0.8 at baseline to 6.7 ± 3.0 with HF (p=0.0002). Conclusions: Hyperglycemia, hyperinsulinemia and insulin resistance develop after the onset of heart failure due to coronary microembolization in dogs consistent with observations previously reported in patients with chronic HF. This large animal model of HF can serve as a useful tool in exploring the underlying causes and consequences of insulin resistance in the setting of chronic HF.