gebhart/patrepeval huggingface dataset:
Action of the cholecystokinin antagonist L364,718 on gastric emptying in the rat (1988)

Cholecystokinin (CCK) is a potent inhibitor of gastric emptying. We have examined the effects of a novel potent peripheral CCK receptor antagonist (L364,718) on the action of endogenous and exogenous CCK octapeptide (CCK-8) on gastric emptying in the rat. In conscious gastric fistula rats, the recovery of liquid test meals of 3.0 ml (containing phenol red as a dilution marker) was determined over periods up to 8 min. Compared with saline, gastric emptying of solutions of peptone (4.5%), 50 mM HCl, and hyperosmolal saline was significantly delayed. The emptying of saline was also delayed by intravenous infusion of CCK-8 (400 pmol.kg-1.h-1). The CCK antagonist L364,718 reversed the effect of peptone in a dose-dependent manner and inhibited the response to exogenous CCK, but the emptying of physiological saline, 50 mM HCl, or hyperosmolal saline remained unchanged. A protease inhibitor (FOY-305) that is thought to release endogenous CCK by inhibiting negative feedback control by luminal proteases also delayed emptying, and this response was inhibited by L364,718. We conclude that CCK has a physiological role in the mediation of the effect of proteins on gastric emptying in the rat.
Clustering Ensemble for Unsupervised Feature Selection (2009)

A new feature selection algorithm for unsupervised learning is proposed. It is based on the assumption that, in absence of class labels, the clustering ensemble result can be employed as a heuristic to guide the feature selection. Therefore, a modified RReliefF algorithm is then used to assign the rankings for every feature. The main advantage of the proposed unsupervised feature selection algorithm in comparison to conventional schemes is that it is dimensionality unbiased. Our experiments with several data sets demonstrate that the proposed algorithm is able to detect completely irrelevant features and to remove some additional features without significantly hurting the performance of the clustering algorithm.
Design of a high-specific speed turbine with non-uniform blade cascade (2019)

This paper presents the hydraulic design of Kaplan type turbine in fully axial configuration. The turbine model consists of a straight pipe intake, a rib which covers the shaft, five axial guide vanes, a six blade runner and a 10,6°-full angle draft tube. Due to the presence of non-uniform velocity field behind the rib and interaction between stator and rotor, the pressure pulsations occur and cause some excitation forces acting on the runner. To reduce these negative phenomena the six non-uniform blade runner has been designed using computational fluid dynamics modelling (CFD). The runner blades are placed in various axial distances from the guide vanes. This new design should reduce the pressure pulsations caused by interaction between the rib and the runner, which is the main negative effect by the current design. The forces and torque which are acting on the runner blades as well as the pressure inside the turbine are observed in time domain. The amplitudes and frequencies are analysed using Fast Fourier Transform (FFT). The frequencies are compared to the modal analysis results of the runner submerged in water. This hydraulic design is based on previous axial turbine, which was designed for small hydro power plant located at Lužnice River. The design point is defined by head H = 1,5 m, volumetric flow rate Q = 2,1 m 3 /s and RPM n = 260 min -1 . This turbine was designed using six runner blades to reduce the pressure, force and torque pulsations caused mainly by wakes, which were observed behind the rib.
Development Of A Flyable Co2 Laser Beacon (1982)

A low cost, four watt CO2 laser intended for use as either an expendable beacon or expendable source for proximity fuses has been developed by the Hughes Aircraft Company. The laser, excited by a 140 MHz rf power supply, has a modulation rate capability extending from dc to more than 100 kHz. The laser, dc-dc converter, and rf power supply weigh less than 1 kg. Although most of the intended applications require the laser to operate for only a few seconds, it has been tested for over 600 hours with negligible power degradation.
Gas-flow model to determine methane production at sanitary landfills (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGas-flow model to determine methane production at sanitary landfillsAn-Hua. Lu and Charles O. KunzCite this: Environ. Sci. Technol. 1981, 15, 4, 436–440Publication Date (Print):April 1, 1981Publication History Published online1 May 2002Published inissue 1 April 1981https://doi.org/10.1021/es00086a007RIGHTS & PERMISSIONSArticle Views168Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (625 KB) Get e-Alerts Get e-Alerts
Synthese von Cyclopamin unter Verwendung biomimetischer und diastereoselektiver Transformationen (2009)

Von Zyklopen und Menschen: Cyclopamin verursacht Zyklopie (äußeres Merkmal: Einäugigkeit) bei Embryos, bei Erwachsenen hat es sich jedoch als wirksames Tumortherapeutikum erwiesen. Cyclopamin ist der erste Inhibitor des Hedgehog-Signaltransduktionsweges. Nun gelang eine biomimetische, diastereoselektive Synthese von Cyclopamin (2) ausgehend von Dehydroepiandrosteron (1), die die Möglichkeit eröffnet, eine Vielzahl von Analoga zu erschließen. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Research on the Adaptive OFDM Hydroacoustic Communication (2023)

Due to the complexity and variability of hydroacoustic channels with long delay multipath propagation, Doppler shift, spectral distortion and non-smoothness, adaptive techniques are used to efficiently use the hydroacoustic channel information to change some parameters of the transmit signal to adapt to the changing channel and thus improve the communication performance. The efficiency of underwater communication systems may be further enhanced by combining the high communication rate, frequency band usage, and multipath resistance of orthogonal frequency division multiplexing (OFDM) technology with multi-carrier wireless communication. We review the development process of adaptive techniques in hydroacoustic communication, and introduce AM based on channel information, power allocation adaptive techniques, joint adaptive bit, modulation and power allocation, combined with reinforcement learning adaptive techniques, respectively. And we analyze the research results of using them in recent years to solve the effects of rapidly changing multipath propagation, fast time-varying, and extended propagation delay in hydroacoustic communication. Our analysis concludes that a multi-carrier OFDM system using link-level adaptive techniques has greater flexibility and can achieve better system performance than a conventional single-carrier system. The basic parameters that can be adjusted include modulation, coding, transmit power, spread spectrum gain and signaling bandwidth. Inaccurate channel state information (CSI) can lead to incorrect modulation schemes, resulting in inefficient communication. Therefore, it is important to effectively obtain accurate CSI as the basis for efficient modulation selection, regardless of the AM method used.
ChemInform Abstract: SYNTHESES OF α‐ETHYNYL‐3,4‐DIHYDROXYPHENYLALANINE AND α‐VINYL‐3,4‐DIHYDROXYPHENYLALANINE (1977)

Abstract 3,4‐Dihydroxy‐benzoesäureester (I) liefert mit Diphenyldichlormethan den cyclischen Ester (II), der nach Reduktion zum Carbinol (IIIa) ein Benzylchlorid (IIIb) gibt, das mit dem Acetylen‐imin (IV) zu einem Substitutionsprodukt (V) führt.
Further Developments in Tunnel Lighting Computations (1991)

(1991). Further Developments in Tunnel Lighting Computations. Journal of the Illuminating Engineering Society: Vol. 20, No. 1, pp. 100-107.
The full-length transcriptome of C. elegans using direct RNA sequencing (2019)

Abstract Current transcriptome annotations have largely relied on short read lengths intrinsic to most widely used high-throughput cDNA sequencing technologies. For example, in the annotation of the Caenorhabditis elegans transcriptome, more than half of the transcript isoforms lack full-length support and instead rely on inference from short reads that do not span the full length of the isoform. We applied nanopore-based direct RNA sequencing to characterize the developmental polyadenylated transcriptome of C. elegans . Taking advantage of long reads spanning the full length of mRNA transcripts, we provide support for 20,902 splice isoforms across 14,115 genes, without the need for computational reconstruction of gene models. Of the isoforms identified, 2,188 are novel splice isoforms not present in the Wormbase WS265 annotation. Furthermore, we identified 16,325 3’ untranslated region (3’UTR) isoforms, 2,304 of which are novel and do not fall within 10 bp of existing 3’UTR datasets and annotations. Combining 3’UTRs and splice isoforms we identified 25,944 full-length isoforms. We also determined that poly(A) tail lengths of transcripts vary across development, as do the strengths of previously reported correlations between poly(A) tail length and expression level, and poly(A) tail length and 3’UTR length. Finally, we have formatted this data as a publically accessible track hub, enabling researchers to explore this dataset easily in a genome browser.
Enhanced Transdermal Delivery of Local Anesthetics by Liposome Formulation of Local Anesthetic Mixture (2005)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
Photooxidative Degradation of Pesticides in Water; Response Surface Modeling Approach (2017)

Abstract The conventional water treatment technologies, mostly relying on physical and biological processes, seem to be inadequate for effective removal of priority substances such as pesticides, while advanced oxidation processes showed a good performance for the same purpose. The aim of the study was to evaluate UV-C/H
A {Global} {Health} {Innovation} {System} ({GHIS}) (2006)

This paper describes a Global Health Innovation System (GHIS) based on research in innovations systems theory.This system would define how concerned countries and institutions could more effectively contribute to health care innovations, especially for the poor in developing countries.Such a system is needed because of the very rapid recent changes in global health innovation.Since the turn of the millennium, the Era of Partnerships has emerged.This era is characterized by the rise of product-development public-private partnerships and is also marked by increased networking, a trend that would benefit from greater coordination and the adoption of a range of best practices.With a comprehensive and compelling GHIS current resources could be allocated more efficiently and additional resources could be mobilized more readily.By integrating innovation with health systems and widened perspectives, the GHIS would help overcome a set of critical health failures: failures of science, failures of the market, and failures of public health systems.It would do so by providing valuable guidance in the planning and management of innovation at the global, regional, national, institutional, and sector levels.The paper concludes by demonstrating how a GHIS could address the health failures by applying the lessons of innovation studies in a structured framework.
Activation of diffusion during the formation of boride layers on the surface of steel parts (2021)

The features of structure formation of diffusion layers obtained by the technology, including preliminary surface treatment of steel products and subsequent thermal diffusion boriding in powder media, have been investigated. Pretreatment consisted in surface activation by superdeep penetration with a powder composition based on SiC of steel samples made of У8 steel. The features of the activation zones and their distribution over the surface are noted. The features of the activation zones and their quantitative characteristics are noted. A structural analysis of the obtained diffusion layers for the variants of low-temperature (650 °C) and high-temperature (920 °C) boration has been carried out. The chemical composition of the layer and the distribution of the main elements in it are analyzed. In both cases, a change in morphology was noted, consisting in the formation of a more compact diffusion layer and rounding of boride needles in the zone adjacent to the base metal. An increase in the layer thickness by 20–50 % and an increase in the proportion of the high-boron FeB phase relative to the variant of borating without preliminary activation were established.
Challenges of Treating Information as a Public Resource: The Case of Parcel Data (2006)

Land parcels are the foundation for many aspects of public and community life. This report presents the findings of a study of information about land parcels in New York State. It identifies stakeholders and their interests as well as the needs and issues associated with the uses of parcel data in the public, private, and nonprofit sectors. We describe the attributes of parcel data, discuss its value to a variety of stakeholders, present typical data flows across organizational boundaries, and illustrate a wide range of uses. We then present the main issues and policy challenges associated with treating parcel data as a collective public resource, and conclude with a set of policy principles for guiding future investments.
Pile-Driving Analysis by the Wave Equation (1962)

There are a great many different pile-driving formulas in use, and engineers have never been able to agree as to which one is best. This situation has arisen primarily because, until recently, the mathematics of pile-driving action could not be solved in any practical manner. As a result all pile-driving formulas are partly empirical and, consequently, apply only to certain types or lengths of pile. This paper is presented with the purpose of giving engineers a mathematical method of wider application, depending on the use of electronic computers and numerical integration. The method is also applicable to other impact problems.
Ultra-compact on-chip LED collimation optics by 3D femtosecond direct laser writing (2016)

By using two-photon lithographic 3D printing, we demonstrate additive manufacturing of a dielectric concentrator directly on a LED chip. With a size of below 200 μm in diameter and length, light output is increased by a factor of 6.2 in collimation direction, while the emission half-angle is reduced by 50%. We measure excellent form fidelity and irradiance patterns close to simulation. Additionally, a more complex shape design is presented, which exhibits a nonconventional triangular illumination pattern. The introduced method features exceptional design freedoms which can be used to tailor high-quality miniature illumination optics for specific lighting tasks, for example, endoscopy.
F-16 automatic test system solution for the aerospace expeditionary force concept (2002)

The recent Aerospace Expeditionary Force (AEF) concept envisions multiple Air Force platforms deploying to hotspots throughout the globe at a moment's notice. Air Force units must be capable of operating mixed force packages at great distances from main operating bases with limited airlift support. Under this scenario, military airlift comes at a premium, and standardization of support equipment across weapon systems becomes vital. Avionics support equipment, traditionally a heavy user of airlift, must be standardized to support the AEF's tenets of light, lean and lethal. Headquarters Air Combat Command has taken the first step to implement this standardization by developing an operational requirements document for an AEF Common Avionics Test System. This system must provide test and repair capability for a wide range of avionics from multiple weapon systems operating in austere conditions. The F-16 has a combat-proven automatic test system currently capable of meeting all its AEF deployment requirements. Based on a series of planned system upgrades scheduled for completion by mid-2002, the F-16 SPO believes its avionics test solution will offer AEF weapon systems an excellent opportunity to capitalize off the F-16's investment and established infrastructure to meet their AEF avionics support deployment requirements with minimal cost technical and schedule risk.
Aggregation of a Polyphilic Janus Polythiophene in Solution (2006)

Solutions of poly(4‘-perfluorooctyl-3-octyl-2,2‘-bithiophene) display strong thermochromism and solvatochromism that are consistent with formation of solid-state-like aggregates. The polyphilicity of the structure (having alkyl, fluoroalkyl, and arene segments) provides a Janus structure in which the two edges of a ribbonlike polymer chain have distinctly different surface energies. In addition, the placement of electron-donating and electron-withdrawing substituents provides an alternation of charge density along the polymer backbone. The chromic effects are not observed for analogous polymers that only have one type of side chain or for an analogue with alternating alkyl and semifluoroalkyl side chains that is polyphilic but does not have the alternation of charge density along the polymer chain.
Analytic Reviews : Hyperbaric Oxygen Therapy (1989)

The physiological effects of hyperbaric oxygen extend beyond the elevation of oxygen concentration in body tissues, and clinical data is available to support its use in more than gas bubble diseases. Hyperbaric medicine is discussed within the context of its recognized mecha nisms of action. The experimental data and clinical ex perience for hyperbaric oxygen therapy are reviewed for the following conditions: clostridial myonecrosis, necrotizing soft-tissue infections, chronic refractory os teomyelitis, radiation necrosis, refractory cutaneous ul cerations, compromised skin grafts and flaps, crush in jury and acute peripheral ischemia, carbon monoxide poisoning, arterial gas embolism, decompression sick ness, and thermal burns. Risks associated with hyper baric oxygen therapy are discussed, and cost analysis data are noted for specific conditions.
synthesis and antibacterial activities of optically active ofloxacin and its fluoromethyl derivative. (1987)

Two optically active (100% enantiomeric excess) isomers (13a and 13b) of ofloxacin (1) [(±) -ofloxacin; DL-8280; (±) -9-fluoro-2, 3-dihydro-3-methyl-10- (4-methyl-1-piperazinyl) -7-oxo-7H-pyrido [1, 2, 3-de] [1, 4] benzoxazine-6-carboxylic acid] and their fluoromethyl derivatives (14a and 14b) were prepared via their optically active intermediates resolved by use of high-performance liquid chromatography (HPLC). The isomers (13a and 13b) were also obtained efficiently by an alternative route via separation of the diastereoisomers (18, 19) prepared in the reaction of benzoxazine (17) with L-prolinyl chloride.The (-) -isomers of 1 and its fluoromethyl derivative (2) were approximately twice as active as the corresponding racemates, while the (+) -isomers were considerably less active than the racemates.The absolute configuration at the C3 position in the oxazine ring in a series of (-) -compounds (b) was confirmed by X-ray analysis of the hydrochloride of the (-) -benzoxazine derivative (15b) to be S.
Assessment of Oxidative Stability and Physical Properties of High Oleic Natural Esters (2019)

Natural esters (triglycerides) possess desirable attributes such as the higher fire points and better environmental compatibility relative to petroleum-derived insulating mineral oil, as a result, the use of such natural esters is on the rise as insulating and heat transfer fluids in electrical devices such as transformers. However, natural esters differ significantly in chemical composition from mineral oils and are more prone to oxidation than mineral oils. High susceptibility of natural esters can be addressed in part through the use of natural esters with higher monounsaturated fatty acid-high oleic natural esters. Recently several high oleic acid soybeans have been introduced commercially. These include Plenish® (Pioneer/Dupont) Vistive Gold® (Monsanto/Bayer) and Soyleic® (Missouri Soybean Association). Both Plenish® and Vistive Gold® are obtained from GMO soybeans, while Soyleic® has been developed through more traditional plant breeding. The oleic acid content of the three natural esters was found to be 79%, 71%, and 81% respectively. While polyunsaturated fatty acid (linoleic and linolenic) contents of the three natural esters were found to be 10.3%, 22.5%, and 7.8% respectively. High oleic soybean oils along with canola oil with oleic content of 75% and polyunsaturated fatty acid content of 17.2% and generic soybean with oleic content of 24.5% and polyunsaturated fatty acid content of 60.0% were subjected to accelerated aging under conditions outlined in IEC 62770 2013. Test results showed that natural esters with higher oleic and lower polyunsaturated acid contents were more stable than the natural esters with lower oleic and higher polyunsaturated content. This stability was reflected in little or no increase in kinematic viscosity and little increase in dissolved acidity. These natural esters are therefore more suitable for dielectric applications where long-term stability is of paramount concern.
Optimizing Camera Stream Transport in Cloud-Based Industrial Robotic Systems (2022)

Combining visual-guided robotics with cloud networking brought a new era into industrial robotic research and development. New challenges have to be tackled with a focus on providing proper communication and data processing setup: sensor data processing as well as the control software should be decoupled from the local robot hardware and should move into the cloud. In the emerging field of cloud robotics, there are trade-offs that have to be handled. More and more sensors such as cameras are being integrated but it comes with a cost. All sensory data have to be sent through often limited networking resources, while latency must be kept as low as possible. In this paper we propose a general solution for efficient camera stream transportation in cloud robotic systems. After introducing our test scenario with the used hardware and software elements, a detailed overview of the architecture is presented with describing each task of the components. The goal of this paper is to examine the current stream transportation implementations in ROS environment and implement a more efficient method. The performance of the proposed method is investigated and compared with other solutions evidenced by measurements.