gebhart/patrepeval huggingface dataset:
Real-Time Charging Navigation of Electric Vehicles to Fast Charging Stations: A Hierarchical Game Approach (2015)

This paper proposes an integrated electric vehicle (EV) charging navigation framework, which takes into consideration the impacts from both the power system and transportation system. The proposed framework links the power system with transportation system through the charging navigation of massive EVs. It benefits the two systems by attracting EVs to charge at off-peak hours and saving the time of EV owners with real-time navigation. Based on the formulated framework, a hierarchical game approach is proposed in this paper to effectively navigate EVs to electric vehicle charging stations (EVCSs). At the upper level of the hierarchical game, a non-cooperative game is proposed to model the competition between EVCSs. Based on the pricing strategies obtained from the non-cooperative game, multiple evolutionary games are formulated at the lower level to evolve EVs' strategies in choosing EVCSs. The simulation results show that the proposed integrated charging navigation approach is effective in improving both the reliability of the power distribution grid and economic profits of the charging stations.
Associations between Maternal Iron Supplementation in Pregnancy and Changes in Offspring Size at Birth Reflect Those of Multiple Micronutrient Supplementation. (2021)

It was previously observed that in a population of a high-income country, dietary multiple micronutrient supplementation in pregnancy was associated with an increased risk of gestational diabetes (GDM) and increased offspring size at birth. In this follow-up study, we investigated whether similar changes are observed with dietary iron supplementation. For this we used the prospective Cambridge Baby Growth Study with records of maternal GDM status, nutrient supplementation, and extensive offspring birth size measurements. Maternal iron supplementation in pregnancy was associated with GDM development (risk ratio 1.67 (1.01-2.77), <i>p</i> = 0.048, <i>n</i> = 677) as well as offspring size and adiposity (<i>n</i> = 844-868) at birth in terms of weight (β' = 0.078 (0.024-0.133); <i>p</i> = 0.005), head circumference (β' = 0.060 (0.012-0.107); <i>p</i> = 0.02), body mass index (β' = 0.067 (0.014-0.119); <i>p</i> = 0.01), and various skinfold thicknesses (β' = 0.067-0.094; <i>p</i> = 0.03-0.003). In a subset of participants for whom GDM statuses were available, all these associations were attenuated by adjusting for GDM. Iron supplementation also attenuated the associations between multiple micronutrient supplementation and these same measures. These results suggest that iron supplementation may mediate the effects associated with multiple micronutrient supplementation in pregnancy in a high-income country, possibly through the increased risk of developing GDM.
Elderly Age as a Prognostic Marker of 1-year Poor Outcome for Subarachnoid Hemorrhage Patients through Its Interaction with Admission Hydrocephalus (2012)

In this observational study, elderly age and admission hydrocephalus predicted poor outcome, but elderly age without hydrocephalus did not. An external validation, however, will be needed to generalize this finding.
Main Mechanism for Stability of THAI-Toe-to-Heel Air Injection (2005)

Abstract THAI, or "Toe-to-Heel Air Injection," is an integrated horizontal well process for in situ recovery and upgrading of heavy oil and tar sands bitumen. During extensive studies of the process at the University of Bath, involving more than 50 three-dimensional combustion cell tests, the process has repeatedly demonstrated robust and stable operation. However, the answer to the question: "Why does oxygen breakthrough into the toe of the horizontal well not occur," has not been fully developed. This is now all the more important since the THAI process is about to be tested in the field. In order to maintain stable propagation of the combustion front, sufficient fuel needs to be available ahead of the front. This is fundamental to the in situ combustion (ISC) process, whether in its conventional form, or THAI. When the combustion front approaches close enough to the horizontal producer well, heavy residue can drain into the well. This residue, or coke material, provides a gas seal, preventing the injected air from channeling through to the well. This paper presents post-mortem results of two THAI experiments, in which the horizontal well was cut-open to reveal the extent of heavy oil residue/coke deposition. The visual evidence is supported also by a numerical simulation of the experiment, showing the distribution of coke and oxygen through the oil layer. Introduction In situ combustion (ISC) has, theoretically, always held the promise of high potential rewards for heavy oil recovery. This is basically because, if a stable combustion front at high temperature (500 - 600 ° C) can be propagated through the oil-bearing formation, virtually all of the heavy oil it contacts is displaced. The fundamental principle of ISC, as applied to heavy oil recovery, is well known, as described by Burger et al.(1). ISC is achieved by burning a small fraction of the oil in the reservoir, which releases sufficient reaction energy to create a large increase in reservoir temperature in the combustion front zone, thereby mobilizing and displacing the oil ahead of it. The chemical reactions between oxygen and crude oil are extremely complex, principally because there are a large number of components which can undergo thermal cracking reactions. The overall complexity of the ISC process is increased because of the interaction between chemical reaction and transport processes in reservoir porous media. Although considerable understanding of the ISC process has been gained in recent years, and new guidelines and strategies for field operations have been presented(2, 3), there are still a number of concerns about the process which need to be resolved if its full operational potential is to be realized. These include:Gravity segregation, or gas overriding;Oil banking in the cold region ahead of the combustion front; and,Permeability heterogeneity. Gas overriding, due to the buoyancy effect between the combustion gases and reservoir liquids, exacerbated by permeability contrasts in the reservoir porous media, can cause severe channeling of gas through to the producer well.
KDM6B is an androgen regulated gene and plays oncogenic roles by demethylating H3K27me3 at cyclin D1 promoter in prostate cancer (2021)

Lysine (K)-specific demethylase 6B (KDM6B), a stress-inducible H3K27me3 demethylase, plays oncogenic or antitumoral roles in malignant tumors depending on the type of tumor cell. However, how this histone modifier affects the progression of prostate cancer (PCa) is still unknown. Here we analyzed sequenced gene expression data and tissue microarray to explore the expression features and prognostic value of KDM6B in PCa. Further, we performed in vitro cell biological experiments and in vivo nude mouse models to reveal the biological function, upstream and downstream regulation mechanism of KDM6B. In addition, we investigated the effects of a KDM6B inhibitor, GSK-J4, on PCa cells. We showed that KDM6B overexpression was observed in PCa, and elevated KDM6B expression was associated with high Gleason Score, low serum prostate-specific antigen level and shorted recurrence-free survival. Moreover, KDM6B prompted proliferation, migration, invasion and cell cycle progression and suppressed apoptosis in PCa cells. GSK-J4 administration could significantly suppress the biological function of KDM6B in PCa cells. KDM6B is involved in the development of castration-resistant prostate cancer (CRPC), and combination of MDV3100 plus GSK-J4 is effective for CRPC and MDV3100-resistant CRPC. Mechanism exploration revealed that androgen receptor can decrease the transcription of KDM6B and that KDM6B demethylates H3K27me3 at the cyclin D1 promoter and cooperates with smad2/3 to prompt the expression of cyclin D1. In conclusion, our study demonstrates that KDM6B is an androgen receptor regulated gene and plays oncogenic roles by promoting cyclin D1 transcription in PCa and GSK-J4 has the potential to be a promising agent for the treatment of PCa.
Expression of CDK7/CAK in normal and tumour cells of diverse histogenesis, cell-cycle position and differentiation (1996)

The cyclin-dependent kinase 7 (CDK7) represents the 40-kDa catalytic subunit of the CDK-activating kinase, the enzyme responsible for activatory phosphorylation of multiple CDKs controlling G1, S and G2/M phases of the cell cycle. Here, we surveyed a wide range of normal and tumour cell types, in both cell culture and biopsy specimens, for abundance and subcellular localisation of the CDK7 protein. Immunoblotting and immunocytochemical analyses showed that CDK7 was (i) ubiquitously expressed in all cell types examined; (ii) exclusively nuclear; (iii) moderately elevated in tumour cells when compared with their normal cell counterparts; (iv) invariant throughout the cell cycle of normal lymphocytes, fibroblasts, breast epithelium and several cancer cell lines; and (v) clearly detectable even in quiescent cells, including highly differentiated cell types in situ. Our data are consistent with the emerging role for CDK7/CAK in multiple biological processes, possibly providing a link between cell-cycle control, transcriptional regulation and genomic integrity control.
Sensor Network-Based and User-Friendly User Location Discovery for Future Smart Homes (2016)

User location is crucial context information for future smart homes where many location based services will be proposed. This location necessarily means that User Location Discovery (ULD) will play an important role in future smart homes. Concerns about privacy and the need to carry a mobile or a tag device within a smart home currently make conventional ULD systems uncomfortable for users. Future smart homes will need a ULD system to consider these challenges. This paper addresses the design of such a ULD system for context-aware services in future smart homes stressing the following challenges: (i) users' privacy; (ii) device-/tag-free; and (iii) fault tolerance and accuracy. On the other hand, emerging new technologies, such as the Internet of Things, embedded systems, intelligent devices and machine-to-machine communication, are penetrating into our daily life with more and more sensors available for use in our homes. Considering this opportunity, we propose a ULD system that is capitalizing on the prevalence of sensors for the home while satisfying the aforementioned challenges. The proposed sensor network-based and user-friendly ULD system relies on different types of inexpensive sensors, as well as a context broker with a fuzzy-based decision-maker. The context broker receives context information from different types of sensors and evaluates that data using the fuzzy set theory. We demonstrate the performance of the proposed system by illustrating a use case, utilizing both an analytical model and simulation.
Direct Deposition of a Rutile Layer on Polymer Substrates to Induce Bioactivity In Vitro (2006)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
Dynamics-aware target following for an autonomous surface vehicle operating under COLREGs in civilian traffic (2013)

We present a model-predictive trajectory planning algorithm for following a target boat by an autonomous unmanned surface vehicle (USV) in an environment with static obstacle regions and civilian boats. The planner developed in this work is capable of making a balanced trade-off among the following, possibly conflicting criteria: the risk of losing the target boat, trajectory length, risk of collision with obstacles, violation of the Coast Guard Collision Regulations (COLREGs), also known as “rules of the road”, and execution of avoidance maneuvers against vessels that do not follow the rules. The planner addresses these criteria by combining a search for a dynamically feasible trajectory to a suitable pose behind the target boat in 4D state space, forming a time-extended lattice, and reactive planning that tracks this trajectory using control actions that respect the USV dynamics and are compliant with COLREGs. The reactive part of the planner represents a generalization of the velocity obstacles paradigm by computing obstacles in the control space using a system-identified, dynamic model of the USV as well as worst-case and probabilistic predictive motion models of other vessels. We present simulation and experimental results using an autonomous unmanned surface vehicle platform and a human-driven vessel to demonstrate that the planner is capable of fulfilling the above mentioned criteria.
Brayton cycle numerical modeling using the RELAP5-3D code, version 4.3.4 (2019)

This work contributes to enable and develop technologies to mount fast microreactors, to generate heat and electric energy, for the purpose to warm and to supply electrically spacecraft equipment and, also, the production of nuclear space propulsion effect. So, for this purpose, the Brayton Cycle demonstrates to be an optimum approach for space nuclear power. The Brayton thermal cycle gas has as characteristic to be a closed cycle, with two adiabatic processes and two isobaric processes. The components performing the cycle's processes are compressor, turbine, heat source, cold source and recuperator. Therefore, the working fluid’s mass flow runs the thermal cycle that converts thermal energy into electrical energy, able to use in spaces and land devices. The objective is numerically to model the Brayton thermal cycle gas on nominal operation with one turbomachine composed for a radial-inflow compressor and turbine of a 40.8 kWe Brayton Rotating Unit (BRU). The Brayton cycle numerical modeling is being performed with the program RELAP5-3D, version 4.3.4. The nominal operation uses as working fluid a mixture 40 g/mole He-Xe with a flow rate of 1.85 kg/s, shaft rotational speed of 45 krpm, compressor and turbine inlet temperature of 400 K and 1149 K, respectively, and compressor exit pressure 0.931 MPa. Then, the aim is to get physical corresponding data to operate each cycle component and the general cycle on this nominal operation.
A Host Defense Mechanism Involving CFTR-Mediated Bicarbonate Secretion in Bacterial Prostatitis (2010)

The CFTR and its mediated HCO(3)(-) secretion may be up-regulated in prostatitis as a host defense mechanism.
Anti‐D alloimmunization after transfusion of D+ red blood cells (2008)

To the Editor: We read with interest the article by González-Porras and colleagues1 about a prospective evaluation of a transfusion policy of D+ red blood cells (RBCs) into D− patients. We would like to address three important findings of the article. First, the authors were able to evaluate for potential alloimmunization 159 D− patients who received D+ RBCs and they identified 34 (21.4%) patients who formed anti-D. However, 19 percent of those patients had a serologic follow-up of between 2 days and 4 weeks. It is important to guarantee that anti-D formation is the result of a primary immunization by D+ RBCs. In nonimmunosuppressed individuals, the earliest time at which anti-D can be detected in primary immunization ranges from 4 to 10 weeks and the production of anti-D within 2 weeks of a first stimulus has been observed only after the injection of specially treated D+ RBCs.2 Therefore, it is not possible to exclude a secondary D immunization in 19 percent of patients and we believe that the true primary immunization in the study by González-Porras and colleagues is lower than reported. Second, the authors only reported the mean number of D+ RBC units (3.2 ± 2.4 units) received by the group of patients who formed anti-D. However, it would be also desirable to know the mean number of D+ RBC units transfused to the group of patients who did not form anti-D. This is because there are published data where the mean number of D+ RBC units transfused was lower in the anti-D former group when compared with the group of patients who did not form anti-D, which would suggest an inverse correlation between probability of antibody formation and number of D+ RBC units given.3 Finally, Gonzalez-Porras and colleagues reported 125 (78.6%) D− patients who did not form anti-D after receiving D+ RBC units and 83 percent of them were followed more than 4 weeks.1 It is important to point out the concept of D−, nonresponder patients who have not been fully characterized by anyone and remains one of the important unresolved issues in Rh biology.4
Temporarily Deferred Therapy (Watchful Waiting) for Men Younger Than 70 Years and With Low-Risk Localized Prostate Cancer in the Prostate-Specific Antigen Era (2005)

No AccessJournal of UrologyUrological survey1 Jan 2006Temporarily Deferred Therapy (Watchful Waiting) for Men Younger Than 70 Years and With Low-Risk Localized Prostate Cancer in the Prostate-Specific Antigen Era C.A. Carter, T. Donahue, L. Sun, H. Wu, D.G. McLeod, G. Amling, R. Lance, J. Foley, W. Sexton, L. Kusuda, A. Chung, D. Soderdahl, S. Jackmaan, and J.W. Moul C.A. CarterC.A. Carter More articles by this author , T. DonahueT. Donahue More articles by this author , L. SunL. Sun More articles by this author , H. WuH. Wu More articles by this author , D.G. McLeodD.G. McLeod More articles by this author , G. AmlingG. Amling More articles by this author , R. LanceR. Lance More articles by this author , J. FoleyJ. Foley More articles by this author , W. SextonW. Sexton More articles by this author , L. KusudaL. Kusuda More articles by this author , A. ChungA. Chung More articles by this author , D. SoderdahlD. Soderdahl More articles by this author , S. JackmaanS. Jackmaan More articles by this author , and J.W. MoulJ.W. Moul More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)00076-5AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Temporarily Deferred Therapy (Watchful Waiting) for Men Younger Than 70 Years and With Low-Risk Localized Prostate Cancer in the Prostate-Specific Antigen Era." The Journal of Urology, 175(1), pp. 266–267 Department of Surgery, Uniformed Services University of Health Sciences, Bethesda, Maryland© 2006 by American Urological AssociationFiguresReferencesRelatedDetails Volume 175Issue 1January 2006Page: 266-267 Advertisement Copyright & Permissions© 2006 by American Urological AssociationMetricsAuthor Information C.A. Carter More articles by this author T. Donahue More articles by this author L. Sun More articles by this author H. Wu More articles by this author D.G. McLeod More articles by this author G. Amling More articles by this author R. Lance More articles by this author J. Foley More articles by this author W. Sexton More articles by this author L. Kusuda More articles by this author A. Chung More articles by this author D. Soderdahl More articles by this author S. Jackmaan More articles by this author J.W. Moul More articles by this author Expand All Advertisement PDF downloadLoading ...
Decremental motor responses to repetitive nerve stimulation in ALS (1994)

Repetitive nerve stimulation (RNS) of the trapezius muscle at slow rates was performed on 192 patients with amyotrophic lateral sclerosis (ALS). Fifty-six patients (29%) showed classical neuromuscular decrement of 10-43% (mean 16.8%) while 44 patients (23%) had a borderline decrement of 5-9%. The trapezius was significantly more sensitive in revealing the defect than the distal hypothenar muscles. In 30 patients followed serially, the decremental response remained constant or increased with time. However, 25% of patients continued to show no decrement in spite of progression of disease. No statistical correlation was found between decrement and clinical severity, disease staging, or disease progression. The finding that at least 50% of ALS patients show some degree of decrement on RNS of the trapezius muscle suggests that functional alterations of the neuromuscular junction accompany this disease.
Chemical and Radiochemical Considerations in Radiolabeling with α-Emitting Radionuclides (2011)

A review of chemical and radiochemical factors that must be considered when radiolabeling targeting agents with radionuclides is presented. The review discusses factors that are important in choice of radionuclide and choice of chelation or bonding reagents to use in the development of an α-emitting radiopharmaceutical. Chemical parameters, such as physical properties and pendant groups for radiolabeling, are reviewed. A major portion of the review outlines the development of chelates and labeling conditions for radiometals, and application of these reagents/conditions to radiometals. Acyclic and macrocyclic chelates containing amine and carboxylic acid coordination groups are highlighted, with examples of bifunctional chelates for biomolecule conjugation. Information is presented on over 60 radiometal-binding chelates. 211At radiolabeling is separated from that of radiometals, and the various reagents used for radiolabeling have been reviewed. Although not all 211At-labeling reagents are reviewed (due to another recent review), nearly 50 reagents studied in the development of pendant groups for labeling with 211At are described. The review also discusses how therapeutic doses of α-emitting radiopharmaceuticals can be affected by the radionuclide used and how radiation damage to the radiopharmaceutical can be minimized.
Simple, Efficient, High- Brightness-LED Control (2007)

Current trends suggest that ongoing improvements in LED technology can produce devices with greater luminous efficacy than fluorescent lamps and eventually, will match HID lamp outputs. HBLEDs already surpass incandescent and halogen lamps’ and provide longer life, greater reliability, smaller size, and superior low-temperature characteristics. Additionally, LEDs are solidstate devices containing neither toxic gases nor filaments. Designers are increasingly using HBLEDs in architectural lighting, street lighting, decorative lighting, signage, and backlighting for high-end televisions and monitors. These applications must derive a regulated DC current from the AC line or DC-voltage supply. International Rectifier’s IRS2540 control IC implements a constant-current source for non-isolated applications. These include, for example, where a low-voltage isolated power supply already exists or where a class-2 fixture houses the LEDs in an inaccessible location, as is the case with traffic lights. This arrangement is similar to electronic ballasts for fluorescent or HID lamps, which typically do not provide galvanic isolation.
Bend measurement using Bragg gratings in multicorefibre (2000)

The first measurements of curvature made using Bragg gratings written in separate cores of a multicore optical fibre are described. The gratings act as independent, but isothermal, strain gauges. The difference in Bragg wavelength between the gratings provides a temperature-independent measurement of the local curvature.
The determination of cholesterol in serum (1952)

P. Trinder, Analyst, 1952, 77, 321 DOI: 10.1039/AN9527700321
Gemeinplätze der Moderne (1997)

Die Welt sah ihre strahlendsten Stadtgebilde immer nur auf eine wohlkalkulierte Entfernung. Sobald aber die auf Abwechslung sinnende Neugier der Neuen Welt näher kam, so indirekt und zugleich so intensiv, wie dies nur einem Leser möglich ist, wurde die Begegnung scheußlich. Aus der Traum. Kein Optimum, nirgends.