gebhart/patrepeval huggingface dataset:
A Potential VEP Biomarker for Mild Cognitive Impairment: Evidence from Selective Visual Deficit of Higher-Level Dorsal Pathway (2016)

Visual dysfunctions are common in Alzheimer's disease (AD). Our aim was to establish a neurophysiological biomarker for amnestic mild cognitive impairment (aMCI). Visual evoked potentials (VEPs) were recorded in aMCI patients who later developed AD (n = 15) and in healthy older (n = 15) and younger controls (n = 15). Visual stimuli were optimized to separately activate lower and higher levels of the ventral and dorsal streams. We compared VEP parameters across the three groups of participants and conducted a linear correlation analysis between VEPs and data from neuropsychological tests. We then used a receiver operating characteristic (ROC) analysis to discriminate those with aMCI from those who were healthy older adults. The latency and phase of VEPs to lower-level stimuli (chromatic and achromatic gratings) were significantly affected by age but not by cognitive decline. Conversely, VEP latencies for higher-ventral (faces and kanji-words) and dorsal (kana-words and optic flow motion) stimuli were not affected by age, but they were significantly prolonged in aMCI patients. Interestingly, VEPs for higher-dorsal stimuli were related to outcomes of neuropsychological tests. Furthermore, the ROC analysis showed that the highest areas under the curve were obtained for VEP latencies in response to higher-dorsal stimuli. These results suggest aMCI-related functional impairment specific to higher-level visual processing. Further, dysfunction in the higher-level of the dorsal stream could be an early indicator of cognitive decline. Therefore, we conclude that VEPs associated with higher-level dorsal stream activity can be a sensitive biomarker for early detection of aMCI.
2.1 &#x003BC;m CW Raman source in GeO<sub>2</sub> fiber (2007)

We report a Raman laser with an output power of 4.2 W at 2.1 μm based upon a 75 mol.% GeO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> doped fiber pumped with CW Thulium doped fiber laser. Potential of 2.3 μm operation is discussed.
Effects of frequency chirp on magnetron injection locking (2008)

In this paper, effects of time-varying frequencies on the injection locking behavior are explored. Of interest is when the driver frequency is linearly swept (chirp) in time, e.g., for frequency search when the oscillator frequency is not known. It is found that complete locking similar to the constant frequency case can no longer occur. Instead, frequency of the oscillator "tracks" the frequency of the driver within the range that is qualitatively predicted by the Adler' s condition. Phase noise for the case in which the free- running frequency fluctuates in time (instead of a linear chirp) is assessed.
Conformation-Specific Spectroscopy and Photodissociation of Cold, Protonated Tyrosine and Phenylalanine (2007)

We present here ultraviolet and infrared spectra of protonated aromatic amino acids in a cold, 22-pole ion trap. Ultraviolet photofragmentation spectra of protonated tyrosine and phenylalanine show vibronically resolved bands corresponding to different stable conformers: two for PheH+ and four in the case of TyrH+. We subsequently use the resolved UV spectra to perform conformer-specific infrared depletion spectroscopy. Comparison of the measured infrared spectra to density functional theory calculations helps assign the geometry of the various conformers, all of which exhibit NH...pi hydrogen bonds and NH...O=C interactions, with the COOH group oriented either anti or gauche to the aromatic ring. In both molecules the majority of the observed fragments result from dissociation on an excited electronic state. In TyrH+, different conformers excited with practically the same energy exhibit different fragmentation patterns, suggesting that the excited-state dynamics depend upon conformation.
High Pressure Science & Technology: Proceedings of the Joint XV AIRAPT and XXXIII EHPRG International Conference Warsaw, Poland, September 11-15, 1995. (1996)

This volume will contain about 40 invited papers and over 200 contributed papers covering all aspects of high-pressure research in physics, chemistry, materials science and biology. It will serve as an exhaustive review of recent achievements in these areas and of the topics of major interest. The list of subjects include: 1) Electronic, optical, and transport properties of solids; 2) Phase transitions, structural properties, and lattice dynamics; 3) Crystal growth and material synthesis; 4) Organic synthesis and biological applications; 5) Geophysical sciences; 6) Instrumentation and metrology; 7) Superhard materials; 8) Ceramics and sintering; 9) Food processing; 10) Plasticity and hydroextrusion.Contributors include: N W Ashcroft (USA), V Blank (Russia), E M Cambell (USA), H G Drickamer (USA), W B Holzapfel (Germany), J Karpinski (Switzerland), H K Mao (USA), W J Nellis (USA), W Paul (USA), E G Ponyatovsky (Russia), A L Ruoff (USA), J S Schilling (USA), O Shimomura (Japan), I F Silvera (USA), B Sundquist (Sweden).
THE MEANING OF THE CHORAL METERS IN SENECAN TRAGEDY (2016)

3. Papiro Michigan inv. 918. -Nel 1925 J. G. Winter pubblico la trascrizione del papiro inv. 918 della Michigan University (,,Classical Philology, 20, 1925, pp. 97-114). Esso contiene i paragrafi 29-35 (rov av&Qwnov . .. ia> raA[Aa]) e 61-68 ('7iQ0oi'6vxoQ...&v d)[rj'dr]') della Ter'a Filippica, e puo essere datato alTinizio del V secolo d. C. Nessuno degli editori di Demostene ha potuto giovarsi delJe varianti di questo papiro. L'unica collazione del quale resta dunque quella di Winter. Ho riletto il papiro su buone riproduzioni fotografiche : la trascrizione di Winter risulta imprecisa in qualche punto. 1) colonna III, rigo 12 (paragrafo 32). Dopo rovg ronovg la sillaba cancellata dal copista in fine di rigo probabilmente non
Supplementary Data 1 from The Shaping of a Polyvalent and Highly Individual T-Cell Repertoire in the Bone Marrow of Breast Cancer Patients (2023)

Supplementary Data 1 from The Shaping of a Polyvalent and Highly Individual T-Cell Repertoire in the Bone Marrow of Breast Cancer Patients
Organometallic chemical vapor deposition of InP/InGaAsP on nonplanar InP substrates: Application to multiple quantum well lasers (1990)

We report the growth of InGaAs and InGaAsP quantum well heterostructures on InP substrates with [011̄] oriented grooves. We have shown that growth of these materials on non-planar substrates can result in lattice-mismatched layers on orientations other than (100) which in some cases gives rise to dislocations. In addition, the lateral patterning of quantum wells and quantum wire-like structures has been demonstrated in this material system. Finally, a quantum well laser, wherein lateral patterning of the well thickness was achieved by growing in a flat-bottomed groove, was fabricated. Without any additional growth steps these lasers exhibit a single stable spatial mode due to the waveguide formed at the groove.
Reaction of Bis(2-chloroethyl) Sulfide with N,N‘-Dichlorobis(2,4,6-trichlorophenyl)urea (1999)

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTReaction of Bis(2-chloroethyl) Sulfide with N,N'-Dichlorobis(2,4,6-trichlorophenyl)ureaD. K. Dubey, R. C. Malhotra, R. Vaidyanathaswamy, and R. VijayaraghavanView Author Information Defence R. & D. Establishment, Jhansi Road, Gwalior 474002 M.P., India Cite this: J. Org. Chem. 1999, 64, 21, 8031–8033Publication Date (Web):September 30, 1999Publication History Received12 May 1999Published online30 September 1999Published inissue 1 October 1999https://pubs.acs.org/doi/10.1021/jo990783ahttps://doi.org/10.1021/jo990783abrief-reportACS PublicationsCopyright © 1999 American Chemical SocietyRequest reuse permissionsArticle Views295Altmetric-Citations18LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Chemical reactions,Chlorine,Oxides,Sulfides,Sulfones Get e-Alerts
Synthesis of 5′-Dithiotriphosphate Derivatives of 3′-Deoxy 3′-Azidothymidine (1991)

Abstract An efficient synthesis of N3TTPαSγS and N3TTPαSβS is described starting from 3′-deoxy 3′azidothymidine.
Clinical and Epidemiological Features of Acute Zika Virus Infections in León, Nicaragua (2021)

The American Zika virus (ZIKV) epidemic has highlighted the need to gain a better understanding of this emerging virus. The goal of this study was to describe the clinical symptoms, laboratory findings, and risk factors for symptomatic ZIKV infection in an area with ongoing transmission of other arboviral infections. We recruited patients at least 2 years of age seeking care at public health centers in León, Nicaragua, between January 2016 and August 2017, for fever, maculopapular rash, and/or nonsuppurative conjunctivitis with a duration of less than 1 week. A laboratory diagnosis of ZIKV was established using a combination of molecular and serological tests. Clinical and laboratory findings and potential risk factors were compared between participants with and without acute ZIKV infection. Fifty-eight (26%) of the 225 participants included in the analysis were found to have acute ZIKV infection. Pregnancy and reports of previous arboviral infection were associated with a higher risk of ZIKV infection. Rash, conjunctivitis, sore throat, and lower absolute neutrophil counts were associated with acute ZIKV infection. The clinical characteristics and risk factors identified were consistent with those identified by previous studies; however, we found sore throat to be a feature of ZIKV infection. We also found that neutrophil counts were lower in ZIKV-infected subjects. These clinical symptoms and laboratory data may help clinicians suspect ZIKV infection during future outbreaks.
Development of a Transformable Plasma Device for Materials Processing (2009)

In this paper, we have developed transformable-sheet electrodes for a capacitively coupled microwave plasma (CCMP) and diagnosed parameters of the CCMP in air, such as the rotational temperature of N <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> (400-600 K at 80-230 torr) and the electron density (approximately 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">13</sup> /cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> at 300 torr). We applied the CCMP to surface modification of polycarbonate to improve the hydrophilic property of the surface. We also performed generation of a homogeneous plasma, which could be of various shapes, developing different transformable-sheet electrodes in air by ac (1.6 kV) at 10 kHz at 3 torr. These results suggested that on-demand plasma processing without an operating gas could be achieved by utilizing transformable-sheet electrode technology.
Altered expression of survivin, Fas and FasL contributed to cervical cancer development and metastasis. (2012)

The up-regulated expression of Survivin and FasL and down-regulated expression of Fas may be involved in the carcinogenesis and development of cervical cancer. The expression of FasL may be one of the prediction indexes for disease progression and prognosis in cervical cancer.
Psychosocial factors associated with childhood bereavement and grief (2005)

While recentadvances in the treatment of HIV disease have resulted in dramatic reductions in morbidity and mortality in the USA [1], in many countries in the Far East and parts of Africa, the aftermath of high AIDS-related mortality has moved the HIV/AIDS epidemic beyond a health crisis. Disruptions to work patterns caused by absenteeism due to illness and funerals, the lack of physical space in morgues and burial grounds, reach deep into everyday life, and are a constant reminder of the fatal nature of this disease [2]. Populations are trying to exist in a state of daily and ongoing loss.
[Features and clinical management of functional somatic syndromes in gynecology]. (2009)

Premenstrual syndrome (and premenstrual dysphoric disorder: PMDD) and chronic pelvic pain (CPP) are considered functional somatic syndromes (FSS) in gynecological practical medicine. Some of them often cannot keep life in society. Painkillers are effective in quite few patient. Therefore psychotherapy is considered essential for the therapy. On certain occasions, complementary and alternative medicine achieve a lasting improvement of pain. At the present time, standard clinical management as well as pathology are not yet established. The practice of integral, whole person, narrative based, and gender specific medicine may be recommended.
An Improved Orthogonal Dirty-Paper Coding Method for Watermarking Applications (2007)

This paper presents an improved orthogonal dirty-paper coding method for digital watermarking applications such as multimedia data authentication or digital rights management The dirty-paper coding is based on the orthogonal Walsh-Hadamard Codes with Binning. Codeword selection is based on maximum correlation to the encoder side information. In contrast to the conventional dirty-paper codes, the encoder side information is based on a constrained extraction of the host data. The decoding error rate expression of the proposed dirty-paper watermarking scheme is derived and verified by simulations to be fairly accurate. It is found that this watermarking method is able to achieve very low visual distortion to host image and very good detection probability for the embedded watermark information.
Facile fabrication of a flower-like CuO/Cu(OH)2 nanorod film with tunable wetting transition and excellent stability (2015)

The digital CA images and the SEM images of the prepared flower-like nanorods surface (A) before and (B) after modification by myristic acid, and (C) after annealing at 200 °C; (D) the schematic of the wetting behavior transition.
How to Cut the Electric Bill in Optical WDM Networks with Time-zones and Time-of-use Prices (2011)

We investigate the benefit of utilizing electric price difference between time intervals of the day for networks covering multiple time-zones. We show that by exploiting this time-and-price variation electric bill can be significantly reduced.
Schottky barrier Ga1−xAlxAs1−ySby alloy avalanche photodetectors (1980)

Schottky barrier avalanche photodiodes have been fabricated in Ga1−xAlxAs1−ySby. The devices are planar and have semitransparent Au barriers. In addition, these detectors exhibit uniform photoresponse and dark current densities of ∼2.7×10−3 A/cm3 at the voltages where avalanche gains of 2 to 4 have been measured. This is the first report of avalanche gain in such a structure in the Ga1−xAlxAs1−ySby alloy system.
PTP1B in complex with TCS401 by Native S-SAD at Room Temperature (2021)

Intermediate processing results used to solve a structure of PTP1B in complex with TCS401 by native S-SAD at room temperature.
Behavior of 3,6‐Bis(vinylsulfonyl)‐1,2,4,5‐tetrafluorobenzene in Homolytic Addition of Dialkyl Phosphites. (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
Optimisation of Nocolok(TM) Brazing Conditions for Higher Strength Brazing Sheet (1997)

&lt;div class="htmlview paragraph"&gt;In non-corrosive flux brazing the flux contains a eutectic mixture of K&lt;sub&gt;3&lt;/sub&gt;AIF&lt;sub&gt;6&lt;/sub&gt;, and KAIF&lt;sub&gt;4&lt;/sub&gt;, which starts to melt at around 560°C. The melted flux disrupts the existing oxide film on aluminium alloys and suppresses further oxidation thus maintaining fluidity of the AI-Si based brazing alloy.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;To facilitate downgauging there is a drive to develop higher strength core alloys. Using alloys with an increased level of magnesium will readily achieve significant improvements in post-brazed strength, however, the brazeability of alloys containing high levels of magnesium deteriorates as a result of magnesium reacting with the flux to form a higher melting point compound, which inhibits fluidity of the molten cladding alloy.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;This paper discusses the influence of brazing conditions to increase tolerance to magnesium in core alloys. Once the optimum brazing conditions are established for varying levels of magnesium, the use of high strength magnesium containing alloys can be exploited for specific components, eg side supports and headers.&lt;/div&gt;
Velocity and attenuation of fast, shear and slow waves in porous media (1990)

The porous materials studied are those described as two-component composites where both the fluid phase and the solid phase are continuous and interpenetrating. The bulk acoustic wave propagation in these materials is shown both theoretically and experimentally to include two types of compressional waves. The fast or normal compressional wave corresponds to an in-phase motion of the fluid and the solid, whereas the slow compressional wave corresponds to an in-phase motion. Highlights of the Biot theory are described as well as some recent velocity and attenuation measurements in one particular kind of porous medium.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Antigenic Structural Similarity as a Predictor for Antibody Cross-Reactivity (2021)

Antibodies are an essential component of the adaptive immune system that function to neutralize foreign invaders,
 such as bacterial and parasitic pathogens. However, B-cell epitopes remain difficult to predict due to their general
 indistinguishability from other protein regions. Epitope prediction tools in the past have largely relied on amino acid
 sequence similarity; however, implementing three-dimensional protein structure analyses into the epitope prediction
 algorithms has been shown to increase detection accuracy. Furthermore, structural comparisons between antigenic
 proteins for their potential to bind cross-reactive antibodies have not been explored extensively in the literature.
 Recent studies have pointed to the utility of looking at shared epitope structures in predicting antibody crossreactivity,
 which may shed light on cross-immunity between infectious pathogens and autoimmune diseases induced
 after infection. Thus, herein, the potential impact of including structural similarity comparisons in detecting shared
 epitopes is discussed. With the large amount of structural information being determined by three-dimensional
 computational protein modelling methods, the ability to perform these analyses is becoming more feasible.
Dose-Dependent Effects of Morphine Exposure on mRNA and microRNA (miR) Expression in Hippocampus of Stressed Neonatal Mice (2015)

Morphine is used to sedate critically ill infants to treat painful or stressful conditions associated with intensive care. Whether neonatal morphine exposure affects microRNA (miR) expression and thereby alters mRNA regulation is unknown. We tested the hypothesis that repeated morphine treatment in stress-exposed neonatal mice alters hippocampal mRNA and miR expression. C57BL/6 male mice were treated from postnatal day (P) 5 to P9 with morphine sulfate at 2 or 5 mg/kg ip twice daily and then exposed to stress consisting of hypoxia (100% N2 1 min and 100% O2 5 min) followed by 2h maternal separation. Control mice were untreated and dam-reared. mRNA and miR expression profiling was performed on hippocampal tissues at P9. Overall, 2 and 5 mg/kg morphine treatment altered expression of a total of 150 transcripts (>1.5 fold change, P<0.05) from which 100 unique mRNAs were recognized (21 genes were up- and 79 genes were down-regulated), and 5 mg/kg morphine affected 63 mRNAs exclusively. The most upregulated mRNAs were fidgetin, arginine vasopressin, and resistin-like alpha, and the most down-regulated were defensin beta 11, aquaporin 1, calmodulin-like 4, chloride intracellular channel 6, and claudin 2. Gene Set Enrichment Analysis revealed that morphine treatment affected pathways related to cell cycle, membrane function, signaling, metabolism, cell death, transcriptional regulation, and immune response. Morphine decreased expression of miR-204-5p, miR-455-3p, miR-448-5p, and miR-574-3p. Nine morphine-responsive mRNAs that are involved in neurodevelopment, neurotransmission, and inflammation are predicted targets of the aforementioned differentially expressed miRs. These data establish that morphine produces dose-dependent changes in both hippocampal mRNA and miR expression in stressed neonatal mice. If permanent, morphine-mediated neuroepigenetic effects may affect long-term hippocampal function, and this provides a mechanism for the neonatal morphine-related impairment of adult learning.
The Schizosaccharomyces pombe mating-type gene mat-Mc encodes a sequence-specific DNA-binding high mobility group box protein. (1993)

The Schizosaccharomyces pombe gene mat-Mc plays a determinative role in the sexual differentiation of the fission yeast. The mat-Mc protein has been suggested to belong to a novel family of so-called high mobility group (HMG) box proteins, characterized by homology to high mobility group-1 and -2 proteins. Several HMG box proteins, including the mammalian sex-determining gene product SRY and the lymphoid transcription factors TCF-1 and LEF-1, have been shown to bind to DNA in a sequence-specific fashion. To analyze possible DNA-binding properties of mat-Mc, we have cloned and expressed its putative HMG box in Escherichia coli. Gel retardation analysis revealed that the mat-Mc HMG box recognizes the AACAAAG heptamer in a sequence-specific fashion. Combined T-->C and A-->I substitutions on both strands of the AACAAAG heptamer, which change the surface of the major groove while leaving the minor groove intact, did not interfere with sequence-specific binding of mat-Mc. Methylation interference analysis confirmed that the mat-Mc HMG box contacts adenine residues in the minor groove. By using a circular permutation assay, the mat-Mc HMG box was observed to bend DNA. These results indicate that mat-Mc is indeed a member of the HMG box family with DNA-binding characteristics assigned earlier to other members of this novel transcription factor family.
Sidelobe behavior and bandwidth characteristics of distributed antenna arrays (2018)

This work investigates sidelobe and bandwidth behavior of various distributed antenna arrays. Two distributions are investigated for unique capabilities in sidelobe tapering. The Bates distribution lowers the sidelobe levels while widening the main beamwidth. By contrast, the Irwin-Hall distribution lowers sidelobe levels, while maintaining mainlobe beamwidth. The three-dimensional sidelobe pattern leads to an energy redistribution. Simulated results for a Circular Lebesgue taper are provided, similar to an Irwin-Hall taper in two-dimensional angular space. A short discussion on 3dB beamwidth with relation to bandwidth properties concludes this paper.