gebhart/patrepeval huggingface dataset:
Delayed reaction to the Dacron buttress used in urethropexy. (1984)

Eleven patients developed a delayed reaction to the Dacron buttress used in Stamey urethropexy. The reaction was characterized by pain, dyspareunia, vaginal discharge and/or bleeding, induration of the abdominal incision, vaginal granulation tissue and draining abdominal or vaginal sinus tracts. This complication occurred in 5% of the 163 patients we treated with the Stamey procedure for stress urinary incontinence. Treatment consisted of removal of the nylon suture and Dacron buttress. None of the 11 patients developed recurrent incontinence. The subjective cure rate for stress urinary incontinence was 92% using the Stamey procedure.
Synthesis and Characterization of Potassium Metal/Graphitic Carbon Nanofiber Intercalates (2008)

Direct reaction of herringbone, platelet, or narrow, tubular herringbone graphitic carbon nanofibers (GCNFs) with molten potassium gives K/GCNF intercalates with stoichiometric control of potassium loading. Intercalate formation is confirmed by powder X-ray diffraction and micro-Raman spectroscopy. K/GCNF intercalates act as radical-anion alkene polymerization catalysts and reduce water with stoichiometric formation of hydrogen gas. Stage-1 K/narrow, tubular GCNF intercalate exhibits thermionic emission at 300 °C. Stage-1 K/herringbone GCNF intercalate is an excellent thermionic emitter having high thermal stability up to 1000 °C. K/GCNF intercalates have much reduced work functions of ca. 2.2 eV with localized emission showing a work function of 1.6 eV.
Kinase activity profiling identifies putative downstream targets of cGMP/PKG signaling in inherited retinal neurodegeneration (2022)

Inherited retinal diseases (IRDs) are a group of neurodegenerative disorders that lead to photoreceptor cell death and eventually blindness. IRDs are characterised by a high genetic heterogeneity, making it imperative to design mutation-independent therapies. Mutations in a number of IRD disease genes have been associated with a rise of cyclic 3',5'-guanosine monophosphate (cGMP) levels in photoreceptors. Accordingly, the cGMP-dependent protein kinase (PKG) has emerged as a new potential target for the mutation-independent treatment of IRDs. However, the substrates of PKG and the downstream degenerative pathways triggered by its activity have yet to be determined. Here, we performed kinome activity profiling of different murine organotypic retinal explant cultures (diseased rd1 and wild-type controls) using multiplex peptide microarrays to identify proteins whose phosphorylation was significantly altered by PKG activity. In addition, we tested the downstream effect of a known PKG inhibitor CN03 in these organotypic retina cultures. Among the PKG substrates were potassium channels belonging to the K<sub>v</sub>1 family (KCNA3, KCNA6), cyclic AMP-responsive element-binding protein 1 (CREB1), DNA topoisomerase 2-α (TOP2A), 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (F263), and the glutamate ionotropic receptor kainate 2 (GRIK2). The retinal expression of these PKG targets was further confirmed by immunofluorescence and could be assigned to various neuronal cell types, including photoreceptors, horizontal cells, and ganglion cells. Taken together, this study confirmed the key role of PKG in photoreceptor cell death and identified new downstream targets of cGMP/PKG signalling that will improve the understanding of the degenerative mechanisms underlying IRDs.
The Glasgow Microenvironment Score associates with prognosis and adjuvant chemotherapy response in colorectal cancer (2020)

This study validates the GMS as a prognostic tool for patients with stage I-III colorectal cancer, independent of TNM, with the ability to stratify both low- and high-risk disease. Furthermore, GMS 0 could be employed to identify a subset of patients that benefit from FOLFOX over CAPOX.
Effects of Hotel Brand Image on Customer Satisfaction and Purchase Intention (2014)

본 연구에서는 호텔브랜드이미지가 고객만족 및 구매의도에 미치는 영향관계를 분석하기 위하여 호텔브랜드이미지의 하위요인으로 호텔서비스, 호텔분위기, 호텔인지도, 전체이미지를 도출하고 실증분석을 실시하였다.BR 실증분석 결과를 요약하면 다음과 같다. 첫째, 호텔브랜드이미지의 호텔서비스, 호텔분위기 요인이 고객만족에 영향을 미치는 것으로 나타났고, 호텔인지도와 전체이미지 요인은 영향을 미치지 않았다. 둘째, 호텔브랜드이미지의 전체이미지, 호텔서비스, 호텔분위기 요인이 구매의도에 영향을 미치는 것으로 분석되었고, 호텔인지도 요인은 영향을 미치지 않았다. 마지막으로, 고객만족은 구매의도에 영향을 미치는 것으로 나타났다.BR 결론적으로, 본 연구는 서울시내 특1급호텔의 이용고객을 대상으로 하였고, 호텔브랜드이미지의 요인들이 고객에 미치는 영향관계를 실증분석 한 의의가 있다 하겠다. 그리고 그동안 주로 연구되어 온 외식분야에서 벗어나 호텔을 대상으로 하여 브랜드이미지를 분석함으로써 호텔고객에게 만족과 다시 이용할 수 있는 전략을 수립하는데 기초적인 자료를 제공한다는 점이 시사점이라 하겠다.
Catabolic Pathways for Streptokinase, Plasmin, and Streptokinase Activator Complex in Mice (1982)

The catabolic pathways of streptokinase, plasmin, and activator complex prepared with human plasminogen were studied in mice. (125)I-streptokinase clearance occurred in the liver and was 50% complete in 15 min. Incubation with mouse plasma had no effect on the streptokinase clearance rate. Complexes of plasmin and alpha(2)-plasmin inhibitor were eliminated from the plasma by a specific and saturable pathway. Competition experiments demonstrated that this pathway is responsible for the clearance of injected plasmin. Streptokinase-plasminogen activator complex formed with either (125)I-plasminogen or (125)I-streptokinase cleared in the liver at a significantly faster rate than either of the uncomplexed proteins (50% clearance in <3 min). Streptokinase incubated with human plasma also demonstrated this accelerated clearance. p-Nitrophenyl-p'-guanidinobenzoate-HCl or pancreatic trypsin inhibitor-treated complex cleared slowly compared with untreated complex independent of which protein was radiolabeled. Significant competition for clearance was demonstrated between alpha(2)-macroglobulin-trypsin and activator complex only when the plasmin(ogen) was the radiolabeled moiety. Large molar excesses of alpha(2)-plasmin inhibitor-plasmin failed to retard the clearance of activator complex. Hepatic binding of streptokinase-plasmin, in liver perfusion experiments, was dependent upon prior incubation with plasma (8-10% uptake compared to a background of approximately 2.5%). Substitution of human alpha(2)-macroglobulin for plasma also resulted in binding when the incubation was performed for 10 min at 37 degrees C (7.5%). Electrophoresis experiments confirmed the transfer of 0.8 mol plasmin/mol alpha(2)-macroglobulin when activator complex was incubated at 37 degrees C with alpha(2)-macroglobulin for 40 min. Streptokinase transfer from activator complex to alpha(2)-macroglobulin was negligible. The in vivo clearance of activator complex is proposed to involve active attack of the complex on the alpha(2)-macroglobulin "bait region," resulting in facilitated plasmin transfer. Dissociated streptokinase is rapidly bound and cleared by sites in the liver.
High-frequency poly(vinylidene fluoride) copolymer transducers used for spectral characterization of settled microparticles (2016)

Abstract High-frequency ultrasonic polymer transducers are used to investigate backscattering from spherical microparticles. These microspheres are immersed in water and allowed to settle on a polymer substrate acting as an ultrasonic contact material between the immersion fluid and the transducer. The experimental study is complemented with a three-dimensional (3D) numerical investigation; both yield rather long scattered waveforms in the time domain for the largest microparticles. The corresponding frequency spectra typically contain a number of minima values arising from wave resonances in the microparticles. The locations of these resonances, or eigenvalues, correlate strongly to the particle size. Good agreement is obtained between the experiment and the numerical model, which will help to identify the wave mode responsible for the extended scattering.
HFE, hepcidin and ferroportin gene mutations are not present in Indian patients with primary haemochromatosis. (2006)

Our patients with primary haemochromatosis lacked mutations in the HFE, hepcidin and ferroportin genes. Further genetic analysis may help identify novel mutations responsible for primary haemochromatosis in these patients.
Repairing the World (2013)

If you are like mecloser to retirement than midcareerafter years of coping with the tragedies of patients with cancer, you are being jolted by the occurrence of malignancies or other serious illnesses in close friends. In response, we might be inclined to reassess the rewards of whatever cancer work we do. There's a case to be made for what could be a radical change in at least some of what we do: We should find other ways to use our skills to repair the world. A translation of the Hebrew phrase tikkun olam, repairing the world suggests social action and the pursuit of social justice. In particular, I urge considering some foreign service.
Effect of partial hydrolysis with an immobilized proteinase on thermal gelation properties of β-lactoglobulin B (2000)

We have investigated the influence of partial hydrolysis with an immobilized proteinase from Bacillus licheniformis on the thermal gelation of isolated beta-lactoglobulin B. Gelation behaviour was determined by dynamic rheological measurements (small deformation) and the gels were characterized with respect to microstructure and water-holding properties. A fine-stranded gel with a complex modulus of approximately 2000 Pa was formed from beta-lactoglobulin (50 g/l in 75 mM-Tris-HCl, pH 7.5). Limited hydrolysis prior to thermal gelation resulted in coarser gels with thicker protein strands and larger pores. Gel structure correlated with its permeability, proton mobility and water-holding capacity. Total stiffness gel increased with low degrees of hydrolysis, but decreased after prolonged hydrolysis. Maximal gel stiffness was 1.5-fold that gels made from of unhydrolysed beta-lactoglobulin. This was much lower than the stiffening effect obtained after partial hydrolysis of whey protein isolate, showing that the gel strengthening effect of partial hydrolysis was depedent on the protein composition and/or the hydrolysis and gelatin conditions. A mechanism to explain the observed effects of hydrolysis on gelation and gel properties is presented.
Development and Application of Scheduling System in Cold Rolling Mills (2003)

The purpose of this research is to develop a scheduling system for CAL (Continuous Annealing Line) in Cold Rolling Mill. Based on CSP (Constraint Satisfaction Problem) technique in artificial intelligence, appropriate algorithms to provide schedules satisfying all the constraints imposed on CAL are designed and developed. Performance tests show that the proposed scheduling system outperforms human operators in case of aggregating the same attributes and minimizing the thickness differences between two adjacent coils.
Terahertz source with graphene p-n junction (2015)

The gate-controlled graphene with two top gates shows that the positive gate voltage can move the Fermi level to higher energy towards conduction band, whereas the negative gate voltage will move the Fermi level to lower energy towards valence band to form graphene p-n junction. The band gap between the n-type graphene and the p-type graphene can be tuned from 0eV. When the induced n-type Fermi level is bigger than 2.15meV, it is possible to radiate terahertz photon if the electrons in n-type graphene are injected to p-type graphene to recombine with holes under a forward bias.
Tratamiento de defectos tipo dehiscencia, usando injertos óseos y barrera con membranas en implantes ya existentes: informe de un caso (2004)

Los defectos de hueso tipo deshicencia podran ocurrir luego de la colocacion de un implante, debido a la accion de microbios, asi como a la sobrecarga oclusal y biomecanica. El objetivo del tratamiento de un defecto periimplante es limitar la progresion de la perdida del hueso y lograr un sitio estable para el implante. En estas situaciones, las menbranas de barrera y materiales paraa el injerto de hueso pueden usarse para lograr una curacion completa del hueso alrededor de los implante dentales. La regeneracion del hueso es posible en un defecto del hueso periimplante de un implante que funciona si se utiliza una tecnica quirurgica adecuada y se elimina la causa de la etiologia. Este estudio presenta la cobertura quirurgica de un defecto de hueso periimplante alrededor de un implante que fue colocado hace 7 anos. La correccion quirurgica se realizo usando una membrana con barrera junto con materiales para el injerto de hueso. El seguimiento de 6 meses revelo la regeneracion radiografica del hueso. Palabras clave: Cobertura. Membrana. Defecto del hueso.
Contour scanning laser vibrometry characterization of Caribbean steelpan (2008)

A conformal scanning laser vibrometer was used to determine the vibrational modes of a 17-note portion of a C-lead tenor steelpan. The data represents the surface-normal motion of the instrument in response to an impulsive excitation intended to mimic the strike of a mallet. A description of this novel measurement system is presented, followed by the surface velocity data and a summary of response shapes and the frequencies at which those responses occur. The data indicate that individual note areas respond when adjacent or non-adjacent notes are struck, and clearly illustrate the complex vibration of the steelpan and the coupling between notes that produce the rich distinctive nature of the steelpan sound.
Effect of Molecular Weight on Performance Properties of Pressure-Sensitive Adhesive of Poly (2-ethylhexyl acrylate) Synthesized by RAFT-Mediated Miniemulsion Polymerization (2015)

Reversible addition-fragmentation chain transfer (RAFT) polymerization has been applied in the synthesis of controlled molecular weights and dispersity of poly (2-ethylhexyl acrylate) (PEHA) by the miniemulsion technique. The RAFT agent (2-cyanoethyl morpholine-4-carbodithioate) was synthesized and used for 2-ethylhexyl acrylate (2-EHA) polymerization at molecular weights of 2 × 105, 7 × 10, 14 × 105, and 20 × 105 Da and polymerization reaction kinetics were studied. The RAFT agent was characterized by Fourier transform infrared (FTIR) spectroscopy, 1H-nuclear magnetic resonance (1H-NMR) spectroscopy, and mass spectroscopy. The synthesized emulsions were characterized by gel permeation chromatography, particle-size analysis, x-ray diffraction (XRD) analysis, and rheological characterization. The PEHAs were used as adhesives for coated and uncoated laminates with low and high surface energies and materials, and their properties such as tack, lap shear strength, peel strength, and shear holding strength were assessed.
Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere (2022)

Summary The point centromere of budding yeast specifies assembly of the large multi-subunit kinetochore complex. By direct attachment to the mitotic spindle, kinetochores couple the forces of microtubule dynamics to power chromatid segregation at mitosis. Kinetochores share a conserved architecture comprising the centromere-associated inner kinetochore CCAN (constitutive centromere-associated network) complex and the microtubule-binding outer kinetochore KMN network. The budding yeast inner kinetochore additionally includes the centromere-binding CBF1 and CBF3 complexes. Here, we reconstituted the complete yeast inner kinetochore complex assembled onto the centromere-specific CENP-A nucleosome (CENP-A Nuc ) and determined its structure using cryo-EM. This revealed a central CENP-A Nuc , wrapped by only one turn of DNA, and harboring extensively unwrapped DNA ends. These free DNA duplexes function as binding sites for two CCAN protomers, one of which entraps DNA topologically and is positioned precisely on the centromere by the sequence-specific DNA-binding complex CBF1. The CCAN protomers are connected through CBF3 to form an arch-like configuration, binding 150 bp of DNA. We also define a structural model for a CENP-A Nuc -pathway to the outer kinetochore involving only CENP-QU. This study presents a framework for understanding the basis of complete inner kinetochore assembly onto a point centromere, and how it organizes the outer kinetochore for robust chromosome attachment to the mitotic spindle.
<title>Electrophotographic Laser Copier Printer Scanner</title> (1983)

Electrophotographic technology allows for the simple incorporation of document scanning. This function is accomplished by monitoring the specular reflection of the toned image on the copier&apos;s photoconductor drum. Documents can be scanned at a rate and resolution comparable to normal electrophotographic printers. Scanning in this way takes advantage of the panchromatic response of the photoconductor, avoids the color-blindness issue of lasers, and prevents exposure of the user to laser radiation. Our experiments show that the principle source of noise in the scanned signal is due to an interference effect in the photoconductor and a detailed description of this effect will be presented.
Investigation of open cylindrical multilayer waveguides filled with biological tissue (2017)

The investigation of open cylindrical multilayer waveguides, analysis of the propagation constant and distribution of electromagnetic fields of waveguides filled with biological tissue are presented in this paper. The investigation is conducted using the Maxwell's equations, coupled mode and partial area methods. The dependencies of complex propagation constant of EM waves of waveguides filled with biological tissue are presented as a result of investigation. The results showed that the highest electromagnetic waves attenuation of the main mode is received, when the concentration of glucose in the blood plasma is equal to 4000 mg/dl. The open cylindrical multilayer waveguides filled with biological tissue could be used for detection of glucose changes in human blood.
Experimental and ab-intio investigations of sub-ps optical excitation effects in amorphous GeTe films (2019)

editorial reviewed
Communication and control in a cluster network (1974)

This paper advocates a certain type of computer network which we call a cluster network. The name is derived from the characteristic topology of the network which consists of processors grouped into clusters. The cluster design presented here assumes that: (1) processors are physically near each other; (2) each processor has a local memory; (3) network control of scheduling, resource allocation, and interprocess communication will be implemented in software.
Dependence of Pt Gate Restructuring on the Linearity of SiC Field Effect Transistor Lambda Sensors (2003)

The increasing size of the car fleet makes it important to find ways of lowering the amounts of pollutants from each individual diesel or gasoline engine to almost zero levels. The pollutants from these engines predominantly originate from emissions at cold start, in the case when gasoline is utilized, and high NOx emissions and particulates from diesel engines. The cold start emissions from gasoline vehicles are primarily due to a high light-off time for the catalytic converter. Another reason is the inability to quickly heat the sensor used for controlling the air-to-fuel ratio in the exhausts, also called the lambda value, which is required to be in a particular range for the catalytic converter to work properly. This problem may be solved utilizing another, more robust sensor for this purpose. One way of treating the high NOx levels from diesel engines is to introduce ammonia in the exhausts and let it react with the NOx in a special catalytic converter to form nitrogen gas and water, which is called SCR (selective catalytic reduction). However, in order to make this system reduce NOx efficiently enough for meeting future legislations, closed loop control is required. To realize this type of system an NOx or ammonia sensor is needed. This thesis presents the efforts made to test the SiC-based field effect sensor device both as a cold start lambda sensor for gasoline engines and as an NH3 sensor for SCR systems in diesel engines. The MISiC (metal insulator silicon carbide) lambda sensor has proven to be both sensitive and selective to lambda, and its properties have been studied in lambda stairs both in gasoline engine exhausts and in the laboratory. There is, however, a small cross-sensitivity to CO. The influence of metal gate restructuring on the linearity of the sensor has also been investigated. The metal tends to form islands by time, which decreases the catalytic activity and thereby gives the sensor, which is binary when fresh, a linear behavior. Successful attempts to prevent the restructuring through depositing a protective layer of insulator on top of the metal were made. The influence of increasing the catalytic activity in the measurement cell was also studied. It was concluded that the location of the binary switch point of MISiC lambda sensors could be moved towards the stoichiometric value if the consumption of gases in the measurement cell was increased. The MISiC NH3 sensor for SCR systems has been shown to be highly sensitive to ammonia both in laboratory and diesel engine measurements. The influence of other diesel exhaust gas components, such as NOx, water or N2O has been found to be low. In order to make the ammonia sensor more long-term stable experiments on samples with different types of co-sputtered Pt or Ir/SiO2 gas-sensitive layers were performed. These samples turned out to be sensitive to NH3 even though they were dense and NH3 detection normally requires porous films. The speed of response for both sensor types has been found to be fast enough for closed loop control in each application.
Insensitivity to the Fungicide Fosetyl-Aluminum in California Isolates of the Lettuce Downy Mildew Pathogen, Bremia lactucae (2004)

Lettuce downy mildew, caused by Bremia lactucae, is the most important foliar disease of lettuce in California. In recent years, there were apparent failures of fungicides containing fosetyl-aluminum (Aliette) to control downy mildew in commercial lettuce fields in California. Consequently, we characterized 134 isolates collected over 2 years from throughout the coastal growing areas of California for insensitivity to the fungicides fosetyl-aluminum and maneb, pathotype, and mating type. Tests using seedlings in controlled growth room conditions demonstrated the widespread occurrence of insensitivity to fosetyl-aluminum in California populations of B. lactucae. Fifty percent of the isolates assayed sporulated profusely in the presence of fosetyl-aluminum applied at rates twice the normal field dosage, and an additional 40% showed moderate sporulation at this rate. Fosetyl-aluminum-insensitive isolates were detected from all regions sampled. Insensitivity was also observed in multiple pathotypes. Insensitivity was not complete, however, because quantitative analysis of the number of lesions on older plants revealed that applications of fosetyl-aluminum could reduce the levels of disease by 50%. Therefore, while fosetyl-aluminum may have utility under low disease pressure in the field, other control measures are required to provide control under conditions favorable to the disease.