gebhart/patrepeval huggingface dataset:
Calibration of Coercive and Stray Fields of Commercial Magnetic Force Microscope Probes (2008)

<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> Variable-field magnetic force microscope (MFM) is introduced to characterize the magnetic behavior of commercially available MFM probes that is relevant to interpret MFM imaging. A Nanotec Electronica S.L. microscope has been conveniently modified to apply magnetic fields in axial direction (up to 1.5 kOe) and in-plane direction (up to 2.0 kOe). Axial and transeverse hysteresis loops of the probes have been generated by measuring the changes in the MFM contrast observed when the magnetic field is applied. The variation of the MFM signal is ascribed to the modification of the magnetic state of the tips. This is enabled by the large coercitivity (∼1.7 kOe) of the checked longitudinal recording media. The properties of the probes depend on the coating material, the macroscopic tip shape, and tip radius. In only a few cases, the magnetization of the probe can be oriented along in-plane orientation. In addition, the stray field of the tips has been deduced by measuring the influence of the probe in the magnetic state of the checked samples. </para>
Clinical Efficacy and Safety of Psoriasis Treatments in Patients with Concomitant Metabolic Syndrome: A Narrative Review (2022)

Metabolic syndrome (MetS) is well recognized as a frequent comorbidity of psoriasis with important implications for efficacy and safety of psoriasis treatment. The presence of concomitant MetS is associated with decreased efficacy response to biologic treatment for psoriasis in observational studies. In post hoc analyses of clinical trial data, the anti-IL-23p19 antibody tildrakizumab appears to maintain efficacy in patients compared to those without MetS; no published subgroup analyses by MetS status are yet available for other biologics. However, there is some evidence that obese patients have decreased psoriasis treatment efficacy with biologics with certain mechanisms of action relative to overweight patients. This confounds interpretation of the effect of MetS due to the association between MetS and body weight. Because of the association between MetS and cardiovascular risk, treatment of psoriasis in patients with concomitant MetS requires special consideration for cardiovascular safety and attention to potential for exacerbation of MetS and related conditions, including nonalcoholic fatty liver disease. Additional studies are needed to clarify the risks for treatment failure and cardiovascular safety concerns in patients with psoriasis and concomitant MetS.
Anticancer and Antibacterial Activities of the Isolated Compounds from Solanum spirale Roxb. Leaves (2012)

The isolations of active anticancer compounds from Solanum spirale Roxb., collected from Phayao Province, Thailand are rarely reported. The anticancer activities of hexane and methanol extracts of the leaves were investigated. The chloroform extract possessed anticancer activities against KB-Oral cavity cancer, MCF-7 breast cancer cell and NCI-H187-Small cell lung cancer with the IC50 values of 42.73, 17.90, and 36.74 μg/ mL, respectively. But the hexane extract did not inhibit significant anticancer activity against three cancer cell lines. Lupeol, protocatechuic acid and trans-cinnamic acid have been isolated from the chloroform extract of this medicinal plants. Their structures were characterized on the basis of spectroscopic analysis. The anticancer activities of the isolated compounds were also evaluated in vitro against three cancer cell lines. Only lupeol compound inhibited significant anticancer activity against KB-Oral cavity cancer with the IC50- value of 26.73 μg/mL, whereas protocatechuic acid and trans-cinnamic acid did not exhibit anticancer activity. The hexane, chloroform extracts and the isolated compounds did not show cytotoxic activity against the African green monkey kidney cell line. The hexane and chloroform extracts also inhibited antibacterial activity against Escherichia coli and Staphylococcus aureus with the MIC values were in the range between 375-1500 μg/mL. All isolated compounds showed equal antibacterial activity against E. coli with the MIC of 250 μg/mL, and trans-cinnamic acid showed better antibacterial activity against S. aureus with the MIC of 250 μg/mL than lupeol and protocatechuic acid. This is the first report decribes the isolation and structure elucidation of lupeol, protocatechuic acid and trans-cinnamic acid together with their anticancer, cytotoxic and antibacterial activities from this medicinal plant.
The genusLactobacillusâ a genomic basis for understanding its diversity (2007)

The genus Lactobacillus is a diverse group that includes many species used in food production and preservation. Some lactobacilli are considered probiotic, conferring health benefits upon the host. The heterogeneity of this genus poses challenges and opportunities when characterizing or exploiting individual strains. To date, 10 Lactobacillus genome sequences have been published, and at least 11 more sequencing projects are ongoing. These studies will dramatically improve one's understanding of metabolic processes, bioprocessing capabilities and potential roles in health and well-being of the Lactobacilli. This review describes the current status of Lactobacillus genome sequence projects, highlights the major findings and summarizes functional genomics or comparative genomics studies. The genomic basis for the unusual diversity of this genus is discussed, and the potential for comparative genomics to rigorously extend phylogenetic analysis of the Lactobacilli is described.
Numerical stress analysis of resin cracking in LSI plastic packages under temperature cyclic loading — Part III: Material properties and package geometries (1998)

In our previous reports [1], [2], geometries of the delaminations which are most likely to lead to resin cracking in large scale integration (LSI) packages subjected to temperature cyclic loading were identified for both Cu alloy and alloy 42 leadframe packages. In this paper, assuming these delaminations, we conduct comprehensive numerical stress analysis of resin cracking to study the effect of properties of encapsulant resin and die-bonding materials and the package geometry factors. The impacts of these design parameters on resin cracking are determined and package design guide is established.
X‐ray emission from CsCl aqueous solutions when irradiated by intense femtosecond laser pulses and its application to time‐resolved XAFS measurement of I − in aqueous solution (2012)

This paper reviews X‐ray emission from electrolyte aqueous solutions when irradiated by intense femtosecond laser pulses in air. First, some examples of X‐ray emission spectra were shown when alkali halide aqueous solutions such as CsCl are used as samples. Dependence of X‐ray emission spectra on laser intensity, solute atomic numbers, and solute concentrations are discussed on the basis of multiphoton ionization, resonance absorption, and so on. Laser chirp effects on X‐ray emission were also discussed for understanding mechanisms occurring during a single laser pulse. X‐ray intensity increase up to 10 3 –10 4 times with prepulse irradiation was also introduced, and the mechanism of X‐ray intensity increase was discussed from the viewpoint of laser ablation induced by the prepulse irradiation. Finally, preliminary results of time‐resolved X‐ray absorption fine spectroscopy using potassium iodide aqueous solution were presented. Copyright © 2012 John Wiley &amp; Sons, Ltd.
A Passive-Telemetry-Based Pressure Sensing System (2002)

This paper presents a wireless battery-free pressure sensing system. The system utilizes a bulk micromachined capacitive pressure sensor along with a capacitive interface circuit implementing passive absorption telemetry. The pressure transducer is based on the dissolved wafer process and has been designed to test the scalability of polysilicon-to-glass anodic bonding. The sensors have been fabricated realizing a 100m-wide bonding ring sealed at wafer level. The sensor interface implements a capacitance-tofrequency converter with a sensitivity of 377Hz/pF for readout of the capacitive pressure sensor and reference capacitors. The wireless system utilizes inductively coupled power and frequency-encoded backscatter modulation for transmission of sensor readout data.
Monocytic U937 Adhesion, Tumor Necrosis Factor-Alpha and Interleukin-1 Beta Expression in Response to Gelatin-Based Networks Grafted with Arginine-Glycine-Aspartic Acid and Proline-Histidine-Serine-Arginine-Asparagine Oligopeptides (2007)

In this study we synthesized gelatin-based, tissue-engineering, interpenetrating network (IPN) scaffolds immobilized with fibronectin (FN)-derived peptides to assess monocyte-biomaterial interaction. Human promonocytic U937 cells were seeded onto peptide-grafted IPN or tissue-culture polystyrene plate (TCPS) pre-adsorbed with FN or FN-derived peptides. The presence of RGD influenced U937 density on IPN. Interleukin-1 beta (IL-1beta) messenger ribonucleic acid (mRNA) expression in adherent U937 on treated TCPS was slightly upregulated at 4 h. Tumor necrosis factor alpha (TNF-alpha) and IL-1beta mRNA expression in adherent U937 on all IPNs was generally downregulated at 4 h. This downregulation of IL-1beta mRNA apparently varied in IPNs grafted with different ligand and was still present at 24 h. TNF-alpha and IL-1beta proteins released from U937 on treated TCPS were comparable with the control at 24 h, but TNF-alpha and IL-1beta protein expression in U937 on IPNs was lower at 24 h than on the TCPS control. The results indicate that the tissue-engineering substrate and the bioactive peptides modulate the initial U937 adhesion and the subsequent inflammatory cytokine gene and protein expression.
Citrulinémia — Heterogeneidade Clínica, Diagnóstico e Tratamento (2014)

São apresentados 5 doentes com Citrulinémia, todos do sexo masculino, 3 com apresentação neonatal (3.5-4.5 dia de vida), 2 mais tardia (19 meses, 3 anos). A idade actual varia entre os 19 meses e os 27 anos (média: 9,5 anos). Três pacientes tiveram coma hiperamoniémico: 2 formas neonatais, outra tardia (6 anos). Todos os doentes tiveram antecedentes de vómitos recorrentes. O doente mais velho fez, no período neonatal (1974), exsanguinotransfusão e diálise peritoneal, todos os outros foram tratados com terapêutica dietética, benzoato de sódio, cloridrato de arginina e carnitina; actualmente todos recebem suplementos de mistura de aminoácidos apropriada. Apenas um doente, com forma neonatal, fez transplante hepático (22 meses). Três doentes apresentam atraso mental: profundo no mais velho (forma neonatal), moderado a ligeiro nas 2 formas mais tardias; 3 têm atraso estaturoponderal. Discutem-se os aspectos mais relevantes quanto ao diagnóstico e tratamento da Citrulinémia.
A Fully Integrated 384-Element, 16-Tile, $W$ -Band Phased Array With Self-Alignment and Self-Test (2019)

This paper describes the design and implementation of a scalable W-band phased-array system, with built-in self-alignment and self-test, based on an RFIC transceiver chipset manufactured in the TowerJazz 0.18-μm SiGe BiCMOS technology with f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> /f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">MAX</sub> of 240/270 GHz. The RFIC integrates 24 phase-shifter elements (16TX/8RX or 8TX/16RX) as well as direct up- and down-converters, phase-locked loop with prime-ratio frequency multiplier, analog baseband, beam lookup memory, and diagnostic circuits for performance monitoring. Two organic printed circuit board (PCB) interposers with integrated antenna sub-arrays are designed and co-assembled with the RFIC chipsets to produce a scalable phased-array tile. Tiles are phase-aligned to one another through a daisy-chained local oscillator (LO) synchronization signal. Statistical analysis of the effects of LO misalignment between tiles on beam patterns is presented. Sixteen tiles are combined onto a carrier PCB to create a 384-element (256TX/128RX) phased-array system. A maximum saturated effective isotropic radiated power (EIRP) of 60 dBm (1 kW) is measured at boresight for the 256 transmit elements. Wireless links operating at 90.7 GHz using a 16-QAM constellation at a reduced EIRP of 52 dBm produced data rates beyond 10 Gb/s for an equivalent link distance in excess of 250 m.
Structure Formation of Integral Asymmetric Composite Membranes of Polystyrene‐block‐Poly(2‐vinylpyridine) on a Nonwoven (2012)

Abstract The formation of an integral asymmetric membrane composed of a cylinder‐forming polystyrene ‐block‐ poly(2‐vinylpyridine) on a nonwoven by using solvent casting followed by solvent/nonsolvent exchange (phase inversion) is reported for the first time. The influence of parameters such as solvent composition, evaporation time of the solution‐cast block copolymer film before phase inversion, and immersion bath temperature is demonstrated. The optimized membranes are characterized in terms of stimuli‐responsive water flux properties. The morphologies of the membranes as well as of the bulk of the block copolymer are imaged by scanning force microscopy, scanning electron microscopy, and transmission electron microscopy. magnified image
Energy conserving protocols for wireless data networks (2001)

In this thesis we study how wireless medium access control (MAC) protocols can be used to conserve energy in wireless portable communication systems. We start by evaluating protocols for centrally controlled networks separately evaluating the protocols used in the management of the exchange of data from those used by nodes to announce to the central controller that they have data to exchange. In the former, we compare different methods of scheduling, methods to announce schedules, and methods to recover from errors. In the latter, we compare various random access and polling techniques. We conclude that there are two significant energy conserving objectives. First, the primary goal of MAC protocols should be to put nodes not participating in data exchanges into a low energy state. Second, information that enables these nodes to enter these states must be made available to them as soon as they can use it. We then consider energy consumption in ad hoc networks. The objectives identified for centrally controlled networks are applicable but are not easily applied because most ad hoc MAC protocols rely on temporally random access techniques. 
As a result, we created a new MAC protocol called Synchronous Collision Resolution (SCR). SCR assumes nodes are synchronized and thus can contend simultaneously. A collision resolution signaling mechanism is used to resolve contentions and request-to-send and clear-to-send exchanges are used to guard against hidden nodes. SCR has many other enhanced capabilities. In particular, the protocol includes a novel priority access scheme and a cooperative signaling approach to robustly support multihop stream based services. The proposed mechanisms for resolving contention are especially effective at identifying a spatially distributed set of transmitting nodes that can exchange data simultaneously. We show through analysis and simulation that the protocol is stable to spatial loads exceeding 40%, avoids congestion collapse, and has spatial capacity exceeding 60%. Moreover, we show that next hop routing strategies and the use of spread spectrum coding can more than double these performance measures. We conclude by arguing that the network can easily adapt to congestion (high load and/or node density) by varying the transmission power used during the contention process. Overall, SCR achieves performance levels in ad hoc networks that have heretofore only been possible for centrally controlled networks.
Anaphylaxis to Pfizer/BioNTech mRNA COVID-19 Vaccine in a Patient With Clinically Confirmed PEG Allergy (2021)

Although allergic responses to the mRNA COVID-19 vaccines are rare, recent reports have suggested that a small number of individuals with allergy to polyethylene glycol (PEG), a component of the mRNA lipid nanoshell, may be at increased risk of anaphylaxis following vaccination. In this report, we describe a case of a patient who received an mRNA COVID-19 vaccine, experienced anaphylaxis, and was subsequently confirmed to have anti-PEG allergy by skin prick testing. The patient had previously noticed urticaria after handling PEG powder for their occupation and had a history of severe allergic response to multiple other allergens. Importantly, as many as 70% of people possess detectable levels of anti-PEG antibodies, indicating that the detection of such antibodies does not imply high risk for an anaphylactic response to vaccination. However, in people with pre-existing anti-PEG antibodies, the administration of PEGylated liposomes may induce higher levels of antibodies, which may cause accelerated clearance of other PEGylated therapeutics a patient may be receiving. It is important to improve awareness of PEG allergy among patients and clinicians.
Two-particle quantum walks applied to the graph isomorphism problem (2010)

We show that the quantum dynamics of interacting and noninteracting quantum particles are fundamentally different in the context of solving a particular computational problem. Specifically, we consider the graph isomorphism problem, in which one wishes to determine whether two graphs are isomorphic (related to each other by a relabeling of the graph vertices), and focus on a class of graphs with particularly high symmetry called strongly regular graphs (SRGs). We study the Green's functions that characterize the dynamical evolution single-particle and two-particle quantum walks on pairs of nonisomorphic SRGs and show that interacting particles can distinguish nonisomorphic graphs that noninteracting particles cannot. We obtain the following specific results. (1) We prove that quantum walks of two noninteracting particles, fermions or bosons, cannot distinguish certain pairs of nonisomorphic SRGs. (2) We demonstrate numerically that two interacting bosons are more powerful than single particles and two noninteracting particles, in that quantum walks of interacting bosons distinguish all nonisomorphic pairs of SRGs that we examined. By utilizing high-throughput computing to perform over 500 million direct comparisons between evolution operators, we checked all tabulated pairs of nonisomorphic SRGs, including graphs with up to 64 vertices. (3) By performing a short-time expansion of the evolution operator, we derive distinguishing operators that provide analytic insight into the power of the interacting two-particle quantum walk.
A run-time power manager exploiting software parallelism (2014)

In this paper we unify the existing power saving techniques: DVFS and DPM (sleep states) and show how an optimized balance between dynamic and static power leads to minimal energy consumption.
Induction Motor Starting in Practical Industrial Applications (2010)

Variable-frequency drives (VFDs) offer smooth and soft motor-starting characteristics. They are widely used in various industrial areas. In this paper, electrical parameters for induction motor starting using VFDs are derived mathematically using the equivalent circuit of induction motors. Factors that could significantly affect the motor-starting performance are investigated. An electrical submersible pump system with various lengths of downhole cables is used as a motor-starting case study.
Assessment of Genetic Purity of Parental Lines of Hybrid Rice Using DNA-Based Markers (2015)

Assessment of hybrid seed genetic purity is one of the most important quality control parameters in hybrid seed production. With the objective of replacing the GOT with DNA based assays, Cytoplasmic Male Sterile (CMS), restorer and hybrid lines have been screened by means of microsatellite and Sequence Tagged Site (STS) markers. Cytoplasmic Male Sterile (CMS) lines often get contaminated with cognate isonuclear maintainer lines during multiplication. The PCR assay was able to detect precisely the impurities in a commercial seed lot of CMS line. The extent of heterozygosity within parental lines of rice hybrids were assessed and the results suggest that a single, appropriately chosen microsatellite marker should be sufficient for assessing hybrid seed purity.
Room temperature terahertz semiconductor frequency comb (2019)

A terahertz (THz) frequency comb capable of high-resolution measurement will significantly advance THz technology application in spectroscopy, metrology and sensing. The recently developed cryogenic-cooled THz quantum cascade laser (QCL) comb has exhibited great potentials with high power and broadband spectrum. Here, we report a room temperature THz harmonic frequency comb in 2.2 to 3.3 THz based on difference-frequency generation from a mid-IR QCL. The THz comb is intracavity generated via down-converting a mid-IR comb with an integrated mid-IR single mode based on distributed-feedback grating without using external optical elements. The grating Bragg wavelength is largely detuned from the gain peak to suppress the grating dispersion and support the comb operation in the high gain spectral range. Multiheterodyne spectroscopy with multiple equally spaced lines by beating it with a reference Fabry-Pérot comb confirms the THz comb operation. This type of THz comb will find applications to room temperature chip-based THz spectroscopy.
Interactive visualization for operational high-resolution weather forecasting at the 1996 centennial Olympic games (1996)

No abstract available.
Faculty Opinions recommendation of Lung opening and closing during ventilation of acute respiratory distress syndrome. (2010)

RATIONALE: The effects of high positive end-expiratory pressure (PEEP) strictly depend on lung recruitability, which varies widely during acute respiratory distress syndrome (ARDS). Unfortunately, increasing PEEP may lead to opposing effects on two main factors potentially worsening the lung injury, that is, alveolar strain and intratidal opening and closing, being detrimental (increasing the former) or beneficial (decreasing the latter).OBJECTIVES: To investigate how lung recruitability influences alveolar strain and intratidal opening and closing after the application of high PEEP.METHODS: We analyzed data from a database of 68 patients with acute lung injury or ARDS who underwent whole-lung computed tomography at 5, 15, and 45 cm H(2)O airway pressure.MEASUREMENTS AND MAIN RESULTS: End-inspiratory nonaerated lung tissue was estimated from computed tomography pressure-volume curves. Alveolar strain and opening and closing lung tissue were computed at 5 and 15 cm H(2)O PEEP. In patients with a higher percentage of potentially recruitable lung, the increase in PEEP markedly reduced opening and closing lung tissue (P < 0.001), whereas no differences were observed in patients with a lower percentage of potentially recruitable lung. In contrast, alveolar strain similarly increased in the two groups (P = 0.89). Opening and closing lung tissue was distributed mainly in the dependent and hilar lung regions, and it appeared to be an independent risk factor for death (odds ratio, 1.10 for each 10-g increase).CONCLUSIONS: In ARDS, especially in patients with higher lung recruitability, the beneficial impact of reducing intratidal alveolar opening and closing by increasing PEEP prevails over the effects of increasing alveolar strain. PMID: 19910610