gebhart/patrepeval huggingface dataset:
Acute C-peptide and insulin response after arginine and glucose infusion. (2015)

&lt;p&gt;&lt;b&gt;A&lt;/b&gt;. Comparison of C-peptide response as a function of time and glucose/arginine stimulation for clinically diagnosed T2D patients antibody positive (insulin±metformin)(n = 7), antibody negative (insulin±metformin) (n = 6) and antibody negative on metformin only (n = 5). Pulses of arginine were administered after clamping plasma glucose at 150, 250 and 500 mg/dL. &lt;b&gt;B&lt;/b&gt;. The area under the curve (AUC) for C-peptide was calculated for the three groups. *p-value&lt;0.0001 for antibody positive &lt;i&gt;vs&lt;/i&gt;. antibody negative groups for all three glucose levels. Error bars indicate SEM. &lt;b&gt;C&lt;/b&gt;. Comparison of acute insulin response (AIR) to arginine at three different plasma glucose levels (150, 250, 500 mg/dL) in antibody positive insulin therapy (n = 7), antibody negatives on insulin ± metformin (n = 6) and antibody negativesmetformin only (n = 5). *p-value&lt;0.05 for antibody positive &lt;i&gt;vs&lt;/i&gt;. antibody negative groups for all three glucose levels. Error bars indicate SEM.&lt;/p&gt;
Typo-Squatting: The Curse'' of Popularity (2009)

Typo-squatting is the practice of registering a domain name with the intent to confuse it with the name of a trademark or a famous other domain name. In this paper we study typo-squatting from a statistical point of view. We introduce the concepts of syntactic and visual neighbourhoods of a domain name as the sets of all other domain names which are, respectively, syntactically or visually similar to the original domain. The results of our preliminary experiments on the '.co.uk' registry show a strong correlation between the popularity of a domain name and the size of its syntactical and visual neighbourhoods. This suggests the size of the neighbourhood can be used as a reliable indicator for the likelihood of being typo-squatted. We conclude the paper with a brief discussion of the implications of our work in the field of online digital identities.
Imaging of Nonmalignant Occupational Lung Disease (2002)

The radiologist plays an important partnership role in detecting presymptomatic disease in those at risk for occupational lung disease, contributing to the specificity of the diagnosis and recognizing sentinel events. Medicolegal roles for imaging include confirming the presence of a morphologic abnormality compatible with occupational lung disease, identifying other potential causes for disability, and determining the morphologic extent of disease. This article describes and illustrates the imaging appearance of a wide range of occupational lung diseases.
Aanvullend waardplantenonderzoek van Meloidogyne fallax Karssen, 1996 (2004)

De wortelknobbelaaltjes Meloidogyne chitwoodi en M.fallax staan op de quarantainelijsten van de EU en de EPPO.De levenswijze van deze nematoden, hun potentiele schade en hun schaarse verspreiding in Europa waren aanleiding voor de quarantaine status. Beide nematoden zijn in Nederland aanwezig. Voor enkele gewassen is waardplantgeschiktheid voor M. chitiwoodi bekend, maar ontbreekt die van M.fallax. Om de uitbrekende gegevens aan te vullen is een aantal gewassen getoetst op hun waardplantgeschiktheid
Clean ferrous casting technology research. Annual report, September 29, 1994--September 28, 1995 (1995)

This annual report covers work performed in the second year of research on Clean Ferrous Casting Technology Research. Significant progress was made in establishing pouring practices which avoid re-oxidation of steel during pouring; application of revised pouring practices have led to reduced inclusion levels in commercially poured steel castings.
Knowledge Representation and Expert Systems for Mineral Processing Using Infobright (2010)

Open source tools for Knowledge Representation in databases and the implementation of a real time expert system for mineral processing operations (size reduction and enrichment) are discussed. The use of a column-oriented database system (Infobright IEE) to store quantitative data from sensors that measure feed size distribution, feed rate, aeration rate, pulp density, pH and temperature allows low latency database query responses and real time process control and analysis. Qualitative metadata can be generated with the use of mathematical process models (simulation outputs, reduction equations, transforms), and from the natural language analysis of process data (reagents and ore mineralogy). The toolkits Wordnet and the Natural Language Toolkit (NLTK) are proposed for metadata generation, processing qualitative text information present in process databases, and for generating data for subsequent inference engine rule checking. We took advantage of the power and ease of the programming language Python to implement a framework for fuzzy and rough set rules generation, and to create an on-line-analytical-processing (OLAP) system for reporting production process parameters.
Effect Of Simulated Facial Movement On The Seal Integrity Of A Valved Holding Chamber Mask (2010)

Method Patients using a pressurized metered dose inhaler (pMDI) require good hand-breath coordination in order to effectively administer a dose of medication. A valved holding chamber (VHC) used with a pMDI can alleviate problems in drug administration for patients with a lack of hand-breath coordination. A facemask is used by patients who are unable to use a VHC with a mouthpiece alone effectively. An effective seal between the patient’s face and the VHC facemask is essential for drug delivery performance as a leak can reduce the dose delivered; 1, 2 therefore, a conforming, leak-preventing design is critical. The range of facial geometries and ages of users of a VHC facemask as well as variation in application during clinical use poses a significant challenge in terms of both facemask design and in vitro testing. In vitro testing can mimic clinical use in such a way as to allow scientifically valid investigations to be performed on operational parameters of device performance and this is an important part of the device development process. Test standards have been developed for the testing of pMDIs with VHCs, but there is no equivalent standardization for VHC facemask testing. In vitro testing of facemasks can be performed using a Soft Anatomical Model (SAM), a soft cast face replica of a 4 year old child (PA Consulting Group, Melbourne, UK) that is formed from an underlying rigid structure overlaid with flexible 10 durometer silicone, to mimic the compliance of fleshy areas of the face. 3-6 The SAM face replica can be fitted to a custom test rig designed to mimic multiple aspects of patient use/misuse (including applied force and angle of application) for in vitro testing of the sealing efficiency of VHC facemasks. The facemask under test is attached to the test rig via custom adapters. These are designed to mimic the original VHC-facemask connection for each facemask. The adapter is attached to a sliding shuttle that allows reproducible application of the facemask to the SAM face replica, which is mounted on the test rig so as to allow for forward/backward movement to ensure accurate positioning under the facemask. At the top of the sliding shuttle, a retaining rod can be loaded with weights to mimic relevant applications of force. 7 The SAM face replica can also be tilted to mimic the range of angles of application that occur during clinical use. Two in-line flow meters positioned on either side of the facefacemask connection determine the peak airflow through the test rig. Effect of Simulated Facial Movement on the Seal Integrity of a Valved Holding Chamber Mask
Distributed task migration for thermal hot spot reduction in many-core microprocessors (2013)

In this paper, we propose a new distributed task migration method to reduce the thermal hot spots and on-chip temperature variance, which leads to better thermal reliability and reduced package costs of emerging many-core processors. The novelty of the new algorithm is that the task migration is done in a fully distributed way while we can still maintain some degrees of global view to guide the process. This is enabled by recently proposed distributed state tracking technique to dynamically estimate the average temperature of all the cores, which provides the important global view of the temperature of the whole chip to efficiently guide local task migration among cores. In addition, the local task migration will be carried out based on the power, temperature, and load influence from neighboring cores. Our experimental results on a 36 core microprocessor demonstrate that the proposed method can reduce 30% more thermal hot spots compared with the existing distributed thermal management method, leading to more balanced temperature distribution of many-core microprocessor chips.
A STUDY ON THE EFFECTIVENESS OF STRUCTURAL CONTROL FOR CABLE-STAYED BRIDGES (1990)

In this paper the effctiveness of passive asn active structural control, for suppressing the dynamic response of cable stayed bridges subjected to earthquake excitations, is investigated. Both the dual passive tuned mass dampers (PTMDs) and the dual active tuned mass dampers (ATMDs) are examined and only the first symmetric and antisymmetric bending modes of bridge vibration are considered; in addition comparison with single TMD is made.
Abstract 320: Procollagen C-Endopeptidase Enhancer Protein 2 Enhances SR-BI Mediated HDL Cholesterol Uptake and Reduces Atherosclerosis in Mice (2015)

Epidemiological studies have shown an inverse correlation between plasma high density lipoprotein (HDL) concentrations and cardiovascular disease risk. At variance with these observations, clinical trials that significantly raised plasma HDL-C levels did not have improved clinical outcomes, emphasizing the importance of understanding HDL function. Recently, a significant correlation has been reported between human procollagen c-endopeptidase enhancer protein 2 (PCPE2) single nucleotide polymorphisms and HDL. PCPE2, a 52 kDa glycoprotein found in the extracellular matrix enhances cleavage of C-terminal procollagen by bone morphogenetic protein 1. Mice lacking PCPE2 have elevated concentrations of enlarged plasma HDL, a phenomenon associated with defective cholesterol efflux. HDL synthesis depends on ABCA1-mediated lipid efflux to lipid-poor apoA-I balanced by cholesterol uptake through hepatic scavenger receptor class B type I (SR-BI). Our studies focused on investigating if the elevated concentration of enlarged plasma HDL in PCPE2 deficient mice was atheroprotective. PCPE2 deficient mice were crossed with LDLr -/- mice (SKO) giving LDLr -/- , PCPE2 -/- (DKO) mice that had elevated HDL levels compared to SKO mice. Despite elevated HDL levels, we found that DKO mice had significantly more lipid and CD68+ infiltration into the aortic root, similar to that reported for LDLr -/- , apoA-I -/- mice that lack plasma apoA-I/HDL. Furthermore, DKO mice showed reduced HDL apoA-I fractional clearance and reverse cholesterol transport rates compared to SKO mice suggesting PCPE2 plays a significant role in HDL remodeling and/or cholesterol uptake by the liver. To test the effect of PCPE2 on SR-BI function we incubated 3 H-cholesteryl ether ( 3 H-CE) enriched HDL from SKO and DKO mice with CHO cells overexpressing PCPE2. Compared to CHO control cells, overexpression of PCPE2 increased 3 H-CE HDL uptake that was independent of HDL particle origin. Western Blot analysis showed no difference in SR-BI expression between control and PCPE2 transfected cells, suggesting that PCPE2 enhanced SR-BI function and promoted HDL cholesterol ester uptake. We conclude that PCPE2 is atheroprotective and an essential component of the reverse cholesterol transport system.
Quantitative analyses of multicomponent fluorescence data by the methods of least squares and non-negative least sum of errors (1977)

Quantitative information can be obtained from fluorescent mixtures using the methods of least squares or linear programming, based on previously determined calibrated excitation-emission matrices (EEM) of known components, even in cases of severe overlap and poor slgnal/noise ratio. The least squares fitting technique was found satisfactory for analysis of a three-component mixture if all components were known. Linear programming, used to minimize the total error with Individual errors constrained to be positive, is preferred when not all components are known. Instrument stability Is a major limitation of accuracy if slow scanning instruments are used. © 1977, American Chemical Society. All rights reserved.
Grain Growth Kinetics of AnBn Star Block Copolymers in Supercritical Carbon Dioxide (2005)

Using a series of AnBn miktoarm star block copolymers with different numbers of arms (n = 1, 2, 4, and 16), the effect of molecular architecture on the grain growth kinetics was investigated by annealing in supercritical carbon dioxide. Across this entire series of materials, all the A arms were polystyrene (PS) blocks from the same anionically synthesized batch, and all the B arms were polyisoprene (PI) blocks from the same anionically synthesized batch. Thus, all the star block copolymers employed in this study were composed of the same A and B arms linked together in symmetric numbers. The grain growth kinetics was monitored in real space by transmission electron microscopy (TEM), followed by subsequent micrograph image analysis. It was found that the molecular architecture influenced the grain growth kinetics of these AnBn star block copolymers significantly. The grain growth kinetics of these AnBn stars annealed in supercritical CO2 was compared to a previously completed grain growth study of the same materials under simple thermal annealing. It was found that the grain growth kinetics for the AnBn stars with n = 2, 4, and 16 were similar for both supercritical CO2 and thermal annealing. However, the grain growth kinetics of the diblock (AnBn with n = 1) was dramatically enhanced in supercritical CO2 relative to thermal annealing.
David Lawrence Sackett, MD, MSc (Epidemiology), 1934–2015 (2015)

ACP Journal Club18 August 2015David Lawrence Sackett, MD, MSc (Epidemiology), 1934–2015R. Brian Haynes, MD, MPH, MACP, Editor, ACP Journal ClubR. Brian Haynes, MD, MPH, MACP, Editor, ACP Journal ClubMcMaster University (R.H.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/ACPJC-2015-163-4-002 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Source CitationDavid Lawrence Sackett, MD, MSc (Epidemiology)References1. A proposal for more informative abstracts of clinical articles. Ad Hoc Working Group for Critical Appraisal of the Medical Literature. Ann Intern Med 1987;106:598–;604. [PMID: PMID: 3826959] Google Scholar2. The James Lind Library. www.jameslindlibrary.org/acp-journal-club-1991/ (accessed 22 Jun 2015). Google Scholar3. Goodreads. www.goodreads.com/quotes/535242-the-farther-back-you-can-look-the-farther-forward-you (accessed 22 Jun 2015). Google Scholar4. David Sackett: Interview in 2014 and 2015. http://fhs.mcmaster.ca/ceb/docs/David_L_Sackett_Interview_in_2014_2015.pdf. Google Scholar5. Unsigned editorial. Evidence based medicine, in its place. Lancet. 1995;346: 785. [PMID: PMID: 7674736] Google Scholar6. Sackett DL, Rosenberg WM, Gray JA, Haynes RB, Richardson WS. Evidence based medicine: what it is and what it isn't. BMJ. 1996;312:71-2. [PMID: PMID: 8555924] Google Scholar Author, Article, and Disclosure InformationAffiliations: McMaster University (R.H.)This article was published at Annals.org on 4 August 2015. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 18 August 2015Volume 163, Issue 4Page: JC2KeywordsClinical epidemiologyEpidemiologyEvidence based medicineGraduate medical educationHealth careHealth services researchMedical servicesNephrologyResearch designResidency ePublished: 18 August 2015 Issue Published: 18 August 2015 Copyright & PermissionsCopyright © 2015 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...
Lessons learned by dismantling two German BWRs (1997)

The body diode degradation in SiC power MOSFETs has been demonstrated to be caused by basal plane dislocation (BPD)-induced stacking faults (SFs) in the drift region. To enhance the reliability of the body diode, many process and structural improvements have been proposed to eliminate BPDs in the drift region, ensuring that commercial SiC wafers for 1.2 kV devices are of high quality. Thus, investigating the body diode reliability in commercial planar and trench SiC power MOSFETs made from SiC wafers with similar quality has attracted attention in the industry. In this work, current stress is applied on the body diodes of 1.2 kV commercial planar and trench SiC power MOSFETs under the off-state. The results show that the body diodes of planar and trench devices with a shallow P+ depth are highly reliable, while those of the trench devices with the deep P+ implantation exhibit significant degradation. In conclusion, the body diode degradation in trench devices is mainly influenced by P+ implantation-induced BPDs. Therefore, a trade-off design by controlling the implantation depth/dose and maximizing the device performance is crucial. Moreover, the deep JFET design is confirmed to further improve the body diode reliability in planar devices.
Synthesis of Optimal Battery State-of-Charge Trajectory for Blended Regime of Plug-in Hybrid Electric Vehicles in the Presence of Low-Emission Zones and Varying Road Grades (2019)

The powertrain efficiency for plug-in hybrid electric vehicles (PHEV) can be maximized by gradually discharging the battery in a blended regime, where the engine is regularly used all over the driving cycle. A key step in designing an optimal PHEV control strategy for the blended regime corresponds to synthesis of battery state-of-charge (SoC) reference trajectory. The paper first demonstrates that the optimal SoC trajectory can significantly differ from a typical linear-like shape in the case of varying road grade and presence of low-emission zones (LEZ). Next, dynamic programming (DP)-based optimizations of PHEV control variables are conducted for the purpose of extracting and analyzing optimal SoC trajectory patterns. It is shown that the optimality is closely related to the minimization of SoC trajectory length with respect to travelled distance. This finding is used for SoC reference trajectory synthesis in the presence of LEZ and varying road grades. Finally, the overall PHEV control strategy is applied to a PHEV-type city bus and verified by means of computer simulations in comparison with the DP optimization benchmark.
The Art of Assembly Language (2003)

Assembly is a low-level programming language that's one step above a computer's native machine language. Although assembly language is commonly used for writing device drivers, emulators, and video games, many programmers find its somewhat unfriendly syntax intimidating to learn and use. Since 1996, Randall Hyde's The Art of Assembly Language has provided a comprehensive, plain-English, and patient introduction to assembly for non-assembly programmers. Hyde's primary teaching tool, High Level Assembler (or HLA), incorporates many of the features found in high-level languages (like C, C++, and Java) to help you quickly grasp basic assembly concepts. HLA lets you write true low-level code while enjoying the benefits of high-level language programming. As you read The Art of Assembly Language, you'll learn the low-level theory fundamental to computer science and turn that understanding into real, functional code. You'll learn how to: Edit, compile, and run an HLA program Declare and use constants, scalar variables, pointers, arrays, structures, unions, and namespaces Translate arithmetic expressions (integer and floating point) Convert high-level control structures This much anticipated second edition of The Art of Assembly Language has been updated to reflect recent changes to HLA and to support Linux, Mac OS X, and FreeBSD. Whether you're new to programming or you have experience with high-level languages, The Art of Assembly Language, 2nd Edition is your essential guide to learning this complex, low-level language.
Rapid Simultaneous Determination of 43 Pesticide Residues in Schizonepeta tenuifolia by Gas Chromatography Mass Spectrometry (2021)

A simple, fast, and reliable method was established for simultaneous determination of 43 pesticides in <i>Schizonepeta tenuifolia</i>. The samples were prepared using solid-phase extraction (SPE) method. Pesticides were extracted from <i>Schizonepeta tenuifolia</i> using acetonitrile, cleaned with Pesticarb/NH<sub>2</sub>, and eluted by mixed solvents of acetonitrile and toluene (3 : 1, v/v). Selected pesticides were identified using DB-35MS capillary column and detected by gas chromatography mass spectrometry. Samples were quantified by external standard method. Recoveries for the majority of pesticides at spike levels of 0.2, 0.5, and 1 mg kg<sup>-1</sup> ranged between 70 and 120% (except for Chlorothalonil, Thiamethoxam, and Dicofol), and the relative standard deviations (RSDs <i>n</i> = 6) were 1.32%-13.91%. Limits of detection (LODs) were 0.0011-0.0135 mg kg<sup>-1</sup>, whereas limits of quantification (LOQs) were 0.0038-0.0451 mg kg<sup>-1</sup>. The satisfactory accuracy and precision, in combination with a good separation and few interferences, have demonstrated the strong potential of this technique for its application in <i>Schizonepeta tenuifolia</i> analysis.
SOMC grafting of vanadium oxytriisopropoxide (VO(OiPr)3) on dehydroxylated silica; analysis of surface complexes and thermal restructuring mechanism (2018)

Vanadium oxytriisopropoxide (VO(O <sup><i>i</i></sup> Pr)<sub>3</sub>), 1, was grafted on highly dehydroxylated silica (SiO<sub>2-700</sub>: aerosil silica treated at 700 °C under high vacuum) to generate compound 2 following the concepts and methodology of surface organometallic chemistry (SOMC). The resulting compound was analyzed by elemental analysis, FT-IR, <sup>1</sup>H, <sup>13</sup>C and <sup>51</sup>V solid state (SS) NMR, Raman and EPR spectroscopies. The grafting reaction of 1 to generate 2 was found to lead to the formation of a monopodal surface complex [([triple bond, length as m-dash]Si-O-)V(O)(O <sup><i>i</i></sup> Pr)<sub>2</sub>], 2m, as well as bipodal [([triple bond, length as m-dash]Si-O-)<sub>2</sub>V(O)(O <sup><i>i</i></sup> Pr)], 2b, formed along with ([triple bond, length as m-dash]Si-O- <sup><i>i</i></sup> Pr) moieties as an effect of the classical rearrangement of 2m with strained siloxane bridges. Upon controlled thermal treatment at 200 °C under high vacuum, 2m and 2b were found to mainly rearrange to tetrahedral VO<sub>4</sub> moieties [([triple bond, length as m-dash]Si-O-)<sub>3</sub>V(O)] (3) with formation of propylene whereas the ([triple bond, length as m-dash]Si-O- <sup><i>i</i></sup> Pr) groups were preserved. The mechanism of the thermal rearrangement of the isopropoxide groups was investigated by a DFT approach revealing the occurrence of a concerted γ-H-transfer and olefin elimination mechanism.