gebhart/patrepeval huggingface dataset:
Data from Phosphorylated Caveolin-1 Regulates Rho/ROCK-Dependent Focal Adhesion Dynamics and Tumor Cell Migration and Invasion (2023)

&lt;div&gt;Abstract&lt;p&gt;Rho/ROCK signaling and caveolin-1 (Cav1) are implicated in tumor cell migration and metastasis; however, the underlying molecular mechanisms remain poorly defined. Cav1 was found here to be an independent predictor of decreased survival in breast and rectal cancer and significantly associated with the presence of distant metastasis for colon cancer patients. Rho/ROCK signaling promotes tumor cell migration by regulating focal adhesion (FA) dynamics through tyrosine (Y14) phosphorylation of Cav1. Phosphorylated Cav1 is localized to protrusive domains of tumor cells and Cav1 tyrosine phosphorylation is dependent on Src kinase and Rho/ROCK signaling. Increased levels of phosphorylated Cav1 were associated with elevated GTP-RhoA levels in metastatic tumor cells of various tissue origins. Stable expression and knockdown studies of Cav1 in tumor cells showed that phosphorylated Cav1 expression stimulates Rho activation, stabilizes FAK association with FAs, and promotes cell migration and invasion in a ROCK-dependent and Src-dependent manner. Tyrosine-phosphorylated Cav1, therefore, functions as an effector of Rho/ROCK signaling in the regulation of FA turnover and, thereby, tumor cell migration and invasion. These studies define a feedback loop between Rho/ROCK, Src, and phosphorylated Cav1 in tumor cell protrusions, identifying a novel function for Cav1 in tumor metastasis that may contribute to the poor prognosis of some Cav1-expressing tumors. [Cancer Res 2008;68(20):8210–20]&lt;/p&gt;&lt;/div&gt;
A mainframe processor in CMOS technology with 0.5 mu m channel length (1990)

A prototype of a processor chip set with a mainframe architecture is implemented using five CMOS standard cell chips. High performance is achieved by wide buses and a RISC- (reduced-instruction-set-computer) like implementation of frequently used instructions. The chip set consists of four units: (1) an instruction processor chip which fetches and decodes the instructions and contains the microcode storage; (2) cache chips which contain the address translation for up to 19 virtual address spaces, a four-way set-associative 16-kByte data/instruction cache, and a 32-B instruction buffer, which is loaded 16 B/cycle from the cache; (3) a fixed-point processor chip which contains the fixed-point registers and arithmetic and a second adder for the address calculation (base+displacement+index); (4) a floating-point processor chip which contains the floating-point registers, multiplier, and arithmetic unit. The processor is based on a four-stage pipeline (five stages for floating-point instructions).< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
The Densities and Surface Tensions of cis- and trans-Decahydronaphthalene between -30 and 180°1 (1941)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Densities and Surface Tensions of cis- and trans-Decahydronaphthalene between -30 and 180°1W. F. Seyer and Charles H. DavenportCite this: J. Am. Chem. Soc. 1941, 63, 9, 2425–2427Publication Date (Print):September 1, 1941Publication History Published online1 May 2002Published inissue 1 September 1941https://doi.org/10.1021/ja01854a031RIGHTS & PERMISSIONSArticle Views129Altmetric-Citations21LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (315 KB) Get e-Alerts Get e-Alerts
The performance of multiuser diversity scheduling for MIMO channels with spatially correlated fading (2006)

We study a cellular network with one multiantenna base station and a number of multiantenna users. Correlated fading may exist at the base station or at the users, or at both sides. With time-varying fading, multiuser diversity is exploited by always allowing the base station to transmit to the user with the best channel. For this network, we find that if the number of transmitter antennas and the number of receiver antennas grow with a fixed ratio, the multiuser diversity gain will approximately remain constant
Effect of complement and its regulation on myasthenia gravis pathogenesis (2007)

Myasthenia gravis (MG) is primarily caused by antibodies directed towards the skeletal muscle acetylcholine receptor, leading to muscle weakness. Although these antibodies may induce compromise of neuromuscular transmission by blocking acetylcholine receptor function or antigenic modulation, the predominant mechanism of injury to the neuromuscular junction is complement-mediated lysis of the postsynaptic membrane. The vast majority of data to support the role of complement derives from experimentally acquired MG (EAMG). In this article, we review studies that demonstrate the central role of complement in EAMG and MG pathogenesis along with the emerging role of complement in T- and B-cell function, as well as the potential for complement inhibitor-based therapy to treat human MG.
Microencapsulated Fragrances in Melamine Formaldehyde Resins (2011)

The process for making melamine formaldehyde microcapsules containing fragrant oil is well-known. Recently, this technology has been used to enhance the olfactory performance on fabrics. However keeping the fragrance in the capsule during storage, improving the olfactory benefit and releasing a low amount of formaldehyde is highly challenging. To answer these challenges, Givaudan has developed its own melamine formaldehyde microcapsule, called Mechacaps, which is described in this article.
Active Optical Waveguides (2018)

Active optical waveguides are the light guiding structures that contain a material possessing optical gain and/or optical nonlinearity that leads to various active functionalities. Stimulated emission of light is a process whereby an atom or a molecule undergoes a transition from higher to lower energy states as a result of the presence of external stimulating photons and is key to the functionalities of both laser emission and optical gain devices. Nonlinearity can lead to establishing active functionalities in waveguide photonic devices such as all-optical switching or optical bistability. Optical gain is a property that a material acquires by exciting its molecules, atoms, or carriers in large densities into higher energy states, resulting in amplification of incident optical power through stimulated emissions. When a semiconductor optical amplifier as an active optical waveguide is used in an optical cavity, lasing takes place as a result of the positive feedback and optical gain.
Development of resistance spot welding technology applying multi-stage adaptive control for narrow pitch spot welding (2019)

Narrow pitch spot welding causes decrease in nugget diameter due to shunting to existing- welds under conventional resistance spot welding. This study aims to develop new resistance spot welding technology for ensuring required nugget diameter regardless of weld spacing. Adaptive control based on real-time feedback of heat quantity was applied for welding of mild steel sheets. However, expulsion occurred from steel sheet surface around the contact edge with electrode when weld spacing was shortened to 10mm. To solve this problem, a new adaptive control method was developed. The method includes 2-stage adaptive control, in which heat quantity is controlled independently in each stage to obtain proper nugget diameter. It is effective to set relatively low heat quantity compared to conventional method in the 1st stage to ensure current pass between steel sheets, and then to apply enough current-flow to obtain proper nugget diameter in the 2nd stage. This method can decrease shunt current flow to existing-welds, and excess increase in welding current and over-heating around contact edge with electrode was suppressed. Appropriate nugget diameter can be consequently ensured without expulsion from steel sheet surface even with 10mm weld spacing.
Mapping of the critical region of mitogene-inducible gene-6 for NF-κB activation (2005)

Mitogene-inducible gene-6 (Mig-6) is involved in the intracellular signaling pathway as an adaptor molecule. Mig-6 expression is rapidly induced upon various kinds of mitogenic and stressful stimulations. We previously demonstrated that Mig-6 expression is induced by activated Ki-ras in human colon cancer cells and the limited proteolytic processed NH(2)-terminal region containing the Cdc42/Rac interaction and binding (CRIB) domain of Mig-6 is bound to IkappaBalpha, resulting in NF-kappaB activation. In this study, we tried to determine the critical region of Mig-6 for regulating NF-kappaB activation by using various kinds of deletion-constructs of Mig-6. The CRIB domain-deleted Mig-6 fragment (residues 68 to 462) did not show significant NF-kappaB activation. Furthermore, NH(2)-terminal 148, 158 and 180 amino acid regions of Mig-6 did not show NF-kappaB activation. On the other hand, the NH(2)-terminal 264 amino acid region of Mig-6 did show NF-kappaB activation to a similar extent of the full length of Mig-6. Interestingly, the full length and NH(2)-terminal 264 amino acid region of Mig-6 produced two kinds of cleaved NH(2)-terminal fragments, N1 and N2 with an approximate molecular size of 5 and 7 kDa, respectively. The NH(2)-terminal 148 and 158 amino acid regions of Mig-6 did not produce N1 or N2 fragments, while the NH(2)-terminal 180 amino acid region of Mig-6 only produced the N1 fragment. Furthermore, the N2 fragment was bound with IkappaBalpha, but the N1 fragment was not. These results together suggested that the NH(2)-terminal 264 amino acid region is critical for NF-kappaB activation and proper limited proteolytic processing of Mig-6.
Statistical PMD Specification - Evolution, Utilization and Control (2005)

Polarization mode dispersion is a primary consideration in today’s telecommunications networks as it can be an important limiter of high data rate and long reach systems. The effective polarization mode dispersion attributed to cabled optical fiber in such systems is dependent not solely upon the maximum individual PMD value, but instead upon the link PMD which is dictated by the PMD distribution of all cabled fibers comprising the link. Taking advantage of the statistical specification of polarization mode dispersion allows one to maximize system efficiency and eliminate unnecessary conservatism. Presented are methods utilized to specify and control PMD which can have a beneficial effect on the cabling process as well as on system design and performance.
Synthesis of Polypyrrole Using Ferric Chloride (FeCl&lt;sub&gt;3&lt;/sub&gt;) as Oxidant Together with Some Dopants for Use in Gas Sensors (2011)

Polypyrrole (Ppy) was synthesized using Ferric Chloride (FeCl3) as oxidant. The ratio of monomer to oxidant was 1:2.4. The polymerization was carried out at 5。C. Attempts were made to increase the electrical conduc-tivity by using various dopants viz. Lithium per Chlorate (LiClO4), para-Toluene Sulfonate (p-TS) and Nap-thalene Sulfonic acid (NSA). The materials were characterized using FTIR, X-Ray diffraction and SEM. The electrical conductivity was measured by two probe method and was found to be in the range of 10-3 to 10-2 S/cm. Thin films of these preparations were casted on the interdigited electrodes to study the detection of gases such as ammonia and LPG. It was found that for the pure Ppy and one doped with LiClO4, when ammonia gas was allowed to flow in, there was a sudden increase in the current, which decreased rapidly when gas was stopped. This behavior is in contradiction to that observed in earlier investigations where Ppy was prepared by electrochemical method. However when Ppy doped with p-TS and NSA were used, the trend was reversed. Similarly it was noted that for pure Ppy and one doped with LiClO4, p-TS and NSA there was an increase in the current when LPG gas was brought in. However the response to LPG was somewhat low as compared ammonia gas.
Discrimination of Apples Using Near Infrared Spectroscopy and Sorting Discriminant Analysis (2015)

Near infrared spectra of apples contain the most useful information of the soluble solids content and firmness of apples. A new feature extraction method, called sorting discriminant analysis, was proposed to use a sorting method based on principal component analysis and linear discriminant analysis to extract the features of near infrared spectra. The objective of this research was to make use of feature extraction methods, such as principal component analysis, linear discriminant analysis, discriminant partial least squares, and sorting discriminant analysis to extract information from near infrared spectra of the "Huaniu" apples and the "Fuji" apples. After feature extraction, the nearest neighbor classifier was used to classify the apples, and the classification results were compared to study that which feature extraction method performed best. The experimental results showed principal component analysis + linear discriminant analysis and sorting discriminant analysis could extract discriminant information from near infrared spectra of apples better than principal component analysis and discriminant partial least squares, and sorting discriminant analysis was the best one. Sorting discriminant analysis can not only compress the high-dimensional near infrared spectra to the low-dimensional data but also project near infrared spectra to a new feature space where the data can be classified easily and effectively, and sorting discriminant analysis is superior to principal component analysis + linear discriminant analysis in most cases.
Intrasinus Administration of Topical Budesonide to Allergic Patients With Chronic Rhinosinusitis Following Surgery (2002)

Topical budesonide delivered through a maxillary antrum sinusotomy tube can control chronic rhinosinusitis that persists after surgery.
A lightweight approach for embedded reconfiguration of FPGAs (2003)

This paper presents a lightweight approach for embedded reconfiguration of Xilinx Virtex II/spl trade/ series FPGAs. A hardware and software infrastructure is reported that enables an FPGA to dynamically reconfigure itself under the control of a soft microprocessor core that is instantiated on the same array. The system provides a highly integrated, lightweight approach to dynamic reconfiguration for embedded systems. It combines the benefits of intelligent control, fast reconfiguration and small overhead.
Two Rerouting-Based Congestion Control Algorithms for Centrally Managed Flow-Oriented Networks (2016)

The evolution of the Internet and fiber-optic technologies has created new opportunities in terms of availability of different network services. The increasing demand for capacity, combined with strong reliability requirements, defines new challenges in the area of network management and design. Today, several users share the limited network resources, which may lead to frequent link congestions in communication networks. Therefore, we propose two effective solutions to respond to link congestions in centrally managed flow-oriented IP networks, such as software-defined networks. We verify their performance through simulation using a real backbone network topology and conclude that as long as enough resources are available in the network, the presented algorithms have the potential to reduce the number of fully loaded links in the network.
Communication—Influence of Carbonate-Based Electrolyte Composition on Cell Performance of SPAN-Based Lithium-Sulfur-Batteries (2018)

Carbonate-based electrolytes were used in combination with sulfurized poly(acrylonitrile)- (SPAN) based lithium-sulfur-cells. High specific capacities of 780 mA⋅h⋅gsulfur−1 after 1050 cycles were reached. A linear correlation between the viscosity of linear symmetric carbonates as solvents in the electrolytes and specific capacity was found. Also, ethylene carbonate and fluorinated ethylene carbonate were compared in terms of cell performance in the cell. Ethylene carbonate-based cells gave the highest discharge capacities of 990 mA⋅h⋅g−1 after 600 cycles.
Engineering Porous Emitting Framework Nanoparticles with Integrated Sensitizers for Low‐Power Photon Upconversion by Triplet Fusion (2019)

The conversion of low-energy light into photons of higher energy based on sensitized triplet-triplet annihilation (sTTA) upconversion is emerging as the most promising wavelength-shifting methodology because it operates efficiently at excitation powers as low as the solar irradiance. However, the production of solid-state upconverters suited for direct integration in devices is still an ongoing challenge owing to the difficulties concerning the organization of two complementary moieties, the triplet sensitizer, and the annihilator, which must interact efficiently. This problem is solved by fabricating porous fluorescent nanoparticles wherein the emitters are integrated into robust covalent architectures. These emitting porous aromatic framework (ePAF) nanoparticles allow intimate interaction with the included metallo-porphyrin as triplet sensitizers. Remarkably, the high concentration of framed chromophores ensures hopping-mediated triplet diffusion required for TTA, yet the low density of the framework promotes their high optical features without quenching effects, typical of the solid state. A green-to-blue photon upconversion yield as high as 15% is achieved: a record performance among annihilators in a condensed phase. Furthermore, the engineered ePAF architecture containing covalently linked sensitizers produces full-fledge solid-state bicomponent particles that behave as autonomous nanodevices.
Cytosolic free calcium and NAD/NADH redox state in the cat cortex during in vivo activation of NMDA receptors (1989)

Activation of the N-methyl-D-aspartate (NMDA) receptors and the concomitant Ca2+ entry have been implicated in neuronal injury in a variety of pathological states. The effects of extracellular Mg2+ concentrations and D,L-2-amino-5-phosphonovaleric acid (APV), a competitive NMDA receptor antagonist on the NMDA-induced responses were investigated in vivo. In vivo fluorometric measurements were made of changes in cytosolic free Ca2+ ([Ca2+]i) and NADH fluorescence directly from the cat cortex using indo-1, a fluorescent Ca2+ indicator. Changes in [Ca2+]i were assessed utilizing the ratio of indo-1 emission at two wavelengths (400 and 506 nm) during excitation with ultraviolet light (340 nm). Application of 100 microM NMDA to the cortex produced a significant increase in the [Ca2+]i signal ratio at physiological concentrations of Mg2+ (1.2 mM). This increase was enhanced in the absence of Mg2+ and was completely blocked either at 5 mM Mg2+ or in the presence of 50 microM APV. The NAD/NADH redox state was initially oxidized, which was also blocked by either high Mg2+ or APV. The application of NMDA elicited characteristic electroencephalogram (EEG) changes consisting of a marked reduction in amplitude and regular spikes (17-20 Hz). These EEG changes did not appear in the presence of APV. In addition to NMDA receptor antagonists, the level of extracellular Mg2+ is a potent physiological modulator of the NMDA response.
Multiplication Noise Characterization of InAlAs-APD With Heterojunction (2009)

The excess noise and ionization coefficient ratio of InAlAs avalanche photodiodes (APDs) with heterojunctions has been measured. To obtain these values accurately, we used a differential amplifier and determined the optical current at which the avalanche multiplication equals 1. These made it possible to conduct measurements on excess noise including that in the low multiplication region. Measured ionization coefficient ratios at <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">M</i> =10 were 0.18 and 0.17 with multiplication layer widths of 0.2 and 0.7 ¿m , respectively. Excess noise was reduced with an increase in the optical input power. This tendency appeared more prominently in APDs with a thin multiplication layer.
ChemInform Abstract: Superconducting Composite Films as Chemical Sensors. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Erbium Lanthanum co-doped fiber for L-band amplifier with high efficiency, low non-linearity and low NF (2001)

We developed ELDF that had high Er concentration, and which attained high efficiency without quenching. We demonstrated that ELDF had high gain per length, low non-linearity at L- band, and low NF comparable to conventional EDF.
Revised specifications and current development status of MIMIZUKU: the mid-infrared instrument for the TAO 6.5-m telescope (2014)

The MIMIZUKU is the first-generation mid-infrared instrument for the TAO 6.5-m telescope. It challenges to prove the origin of dust and the formation of planets with its unique capabilities, wide wavelength coverage and precise calibration capability. The wide wavelength coverage (2-38 &mu;m) is achieved by three switchable cameras, NIR, MIR-S, and MIR-L. The specifications of the cameras are revised. A 5&mu;m-cutoﬀ HAWAII-1RG is decided to be installed in the NIR camera. The optical design of the MIR-L camera is modified to avoid detector saturation. Its final F-number is extended from 5.2 to 10.5. With these modifications, the field of view of the NIR and MIR-L camera becomes 1.2’ × 1.2’ and 31” × 31”, respectively. The sensitivity of each camera is estimated based on the revised specifications. The precise calibration is achieved by the “Field Stacker” mechanism, which enables the simultaneous observation of the target and the calibration object in diﬀerent fields. The up-and-down motion of the cryostat (~ 1 t), critical for the Field Stacker, is confirmed to have enough speed (4 mm/s) and position accuracy (~ 50 &mu;m). A control panel for the Field Stacker is completed, and its controllers are successfully installed. The current specifications and the development status are reported.
Solar cell efficiency tables (version 13) (1999)

Consolidated tables showing an extensive listing of the highest independently confirmed efficiencies for solar cells and modules are presented. Guidelines for inclusion of results into these tables are outlined and new entries since July 1998 are briefly described. Copyright © 1999 John Wiley & Sons, Ltd.