gebhart/patrepeval huggingface dataset:
Granting three wishes through performance-centered design (1997)

article Free Access Share on Granting three wishes through performance-centered design Author: Gloria Gery Gery Associates, Tolland, Mass. Gery Associates, Tolland, Mass.View Profile Authors Info & Claims Communications of the ACMVolume 40Issue 7July 1997pp 54–59https://doi.org/10.1145/256175.256185Published:01 July 1997Publication History 14citation651DownloadsMetricsTotal Citations14Total Downloads651Last 12 Months19Last 6 weeks1 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Cuisson au sulfite semi-alcalin de bouleau blanc : cinétique, mécanisme de réaction et propriétés papetières (1991)

permet une conomie de 42,24 $CAN.par tonne de pte et une augmentation de productivit de 14% pour une pte aux proprits physiques quivalentes une pte kraft mais un nombre Kappa beaucoup plus lev.
Cannabidiol inhibits paclitaxel‐induced neuropathic pain through 5‐HT1A receptors without diminishing nervous system function or chemotherapy efficacy (2013)

Our data suggest that CBD is protective against PAC-induced neurotoxicity mediated in part by the 5-HT(1A) receptor system. Furthermore, CBD treatment was devoid of conditioned rewarding effects or cognitive impairment and did not attenuate PAC-induced inhibition of breast cancer cell viability. Hence, adjunct treatment with CBD during PAC chemotherapy may be safe and effective in the prevention or attenuation of CIPN.
Design and construction of a uniaxial cell stretcher (2000)

In vitro mechanical cell stimulators are used for the study of the effect of mechanical stimulation on anchorage-dependent cells. We developed a new mechanical cell stimulator, which uses stepper motor technology and computer control to achieve a high degree of accuracy and repeatability. This device also uses high-performance plastic components that have been shown to be noncytotoxic, dimensionally stable, and resistant to chemical degradation from common culture laboratory chemicals. We show that treatment with glow discharge for 25 s at 20 mA is sufficient to modify the surface of the rubber to allow proper adhesion for polymerization of aligned collagen. We show through finite element analysis that the middle area of the membrane, away from the clamped ends, is predictable, homogeneous, and has negligible shear strain. To test the efficacy of the mechanical stretch, we examined the effect of mechanical stimulation on the production of beta(1)-integrin by neonatal rat cardiac fibroblasts. Mechanical stimulation was tested in the range of 0-12% stretch and 0-10-cycles/min stretch frequency. The fibroblasts respond with an increase in beta(1)-integrin at 3% stretch and a decrease at 6 and 12% stretch. Stretch frequency was found to not significantly effect the concentration of beta(1)-integrin. These studies yield a new and improved mechanical cell stimulator and demonstrate that mechanical stimulation has an effect on the expression of beta(1)-integrin.
Posttransplant renal rejection: comparison of quantitative scintigraphy, US, and MR imaging. (1987)

Accuracy of ultrasonography (US), quantitative scintigraphy, and magnetic resonance (MR) imaging in diagnosis of acute renal allograft rejection was studied in 46 patients who underwent renal biopsy. Thirty-three patients had acute rejection; six, cyclosporine nephrotoxicity, as shown by biopsy, clinical findings, and follow-up study; two, acute tubular necrosis; and five, normal biopsy findings and renal function. Accuracy in demonstrating rejection was 72% for US and 75% for scintigraphy, indicating no significant difference between the two. MR imaging was significantly more accurate, reaching a level of 98%. However, accuracy of MR in demonstrating acute tubular necrosis in a larger number of patients is not known, and its accuracy in indicating recurrent glomerulopathy or infectious disease has not been addressed. The definitive role of MR in evaluating posttransplant renal failure is currently not established, but because of its high sensitivity in detecting renal abnormality, MR can be used for cases when results of US or scintigraphy are equivocal or contradict clinical impressions or when biopsy cannot be performed for medical reasons.
Supplemental Tables S1-3, Supplemental Figures S1-8 from Characterization and Evidence of the miR-888 Cluster as a Novel Cancer Network in Prostate (2023)

&lt;p&gt;This supplemental data file consists of 3 supplemental tables and 8 supplemental figures. Suppl. Tables 1-2 lists specific miRNA mimics, inhibitors, TaqMan and PCR primers used in the in vitro functional assays depicted in Figs. 1-4, 6-7. Suppl. Table 3 provides a phenotypic summary of the in vitro assays in Figs. 2-4. Suppl. Fig. 1 shows characterization of exosomes secreted from PC3-derived cell lines profiled in Fig. 1C. Suppl. Figs. 2-4 confirms miR-888 and miR-891a misexpression using miRNA mimics, miRNA inhibitors, and lentiviral miRNA mimic reagents in human prostate cells analyzed in Figs. 2-7. Suppl. Fig. 5 represents predicted miR-888 and miR-891a binding sites found in the 3'UTR regions of RBL1, SMAD4, KLF5, and TIMP2 transcripts validated in Fig. 6A using luciferase reporter assays. Suppl. Fig. 6 indicates that miR-888 targets RBL1, SMAD4, KLF5, and TIMP2 possess cell type specific expression in LNCaP when compared to PC3-N cells in Fig. 6B-C. Suppl. Fig. 7 shows functional evidence that miR-888 targets RBL1 and TIMP2 to control proliferation and invasion activities assayed in Figs. 2-3. Suppl. Fig. 8 implicates that miR-888 and miR-891a act synergistically to regulate prostate cell proliferation depicted in Fig. 2 and provides a model of how the miR-888 cluster regulates prostate cancer progression.&lt;/p&gt;
Adaptive Bayesian optimization for epitaxial growth of Si thin films under various constraints (2020)

We applied a Bayesian optimization (BO) to optimize the epitaxial growth process of Si thin films. The BO enables us to effectively explore the optimal film growth conditions considering several experimental parameters and their interactions. In this way we reduced the total number of experiments required in the optimization. The epitaxial growth rate was maximized while five quality parameters were maintained within an acceptable range. Additionally, we considered two practical issues: eliminating equipment errors and the time cost of the quality parameter evaluation. To overcome these issues, we adaptively conducted BO with different constraints for different situations. As a result of these optimizations, the crystal growth rate was increased to be approximately twice as high as that under standard conditions, while satisfying the five quality parameter conditions.
Studies on the subcellular localization and properties of bis(monoacylglyceryl)phosphate biosynthesis in rat liver. (1976)

<P>Abstract copyright UK Data Service and data collection copyright owner.</P>The <i>National Cancer Patient Experience Surveys</i> (NCPES) began in 2010, after the 2007 'Cancer Reform Strategy' set out a commitment to establish a new survey programme. The NCPES is intended to be a vehicle enabling and supporting quality improvement in the NHS and has been used by national bodies, NHS Hospitals, specialist cancer teams, and national and condition specific charities to improve services for patients. It is designed to monitor national progress on cancer care and to help gather vital information on the Transforming Inpatient Care Programme, the National Cancer Survivorship Initiative and the National Cancer Equality Initiative. An Advisory Group was set up for the NCPES with the National Cancer Director, professionals, voluntary sector representatives, academics and patient survey experts. The Group agreed on the following guiding principles and objectives:<ul><li>a standard national survey tool was to be used</li><li>surveys would be conducted at Trust level and identify cancer groups</li><li>the survey would cover all cancers and include the whole care pathway</li><li>the survey should use the word 'cancer' unlike the 2000 and 2004 surveys</li><li>the survey focus would be on patients (rather than carers)</li><li>the data would be used for benchmarking performance across Trusts and by cancer groups where numbers allow</li><li>the data would be used to inform national and local policy</li><li>the data would be made publicly available whilst observing patient data protection requirements and maintaining confidentiality.</li></ul> The survey is intended to be a vehicle enabling and supporting quality improvement in the NHS and has been used by national bodies, NHS Hospitals, specialist cancer teams, and national and condition specific charities to improve services for patients. <br> <br>The NCPES has been replicated in Wales (see SN 7510), Northern Ireland, the Isle of Man, parts of Australia, and the Middle East. Further information can be found on the Quality Health Limited <a href="http://www.quality-health.co.uk/surveys/national-cancer-patient-experience-survey" title="National Cancer Patient Experience Survey">National Cancer Patient Experience Survey</a> webpage and the <a href="https://www.england.nhs.uk/statistics/statistical-work-areas/cancer-patient-experience-survey" title="NHS England Cancer Patient Experience Survey">NHS England Cancer Patient Experience Survey</a> webpage.<br> <br> <b>2010-2015 surveys temporarily withdrawn</b><br> The data for the 2010-2014 surveys were temporarily withdrawn at the request of the depositor in October 2015. The 2015 data (SN 8163 and the Special Licence version, SN 8164)&nbsp;&nbsp;were temporarily withdrawn at the request of the depositor in&nbsp;February 2020.<br> <br>
Passive Heat Transfer Enhancement in Microchannels Using Wall Features (2007)

The two important considerations in the design of a heat exchanger are — the total heat transfer rate and the allowable pressure drop. The allowable pressure drop defines the maximum flow rate through a single microchannel and economics drives the design towards this flow rate. Typically the flow rate in the microchannel is in laminar flow regime (Re &lt; 2000) due to smaller hydraulic diameter. The laminar flow heat transfer in a smooth microchannel is limited by the boundary layer thickness. Commonly the heat transfer rate is enhanced by passively disrupting the laminar boundary layer using protrusions or depressions in the channel walls. More often these methods are best applicable at small range of Reynolds number where the heat transfer rate enhancement is more than the pressure drop increase and break down as the flow rate is changed outside the range. The benefit of a flow disruption method can be reaped only if it provides higher heat transfer enhancement than the increase in the pressure drop at the working flow rates in the microchannel. A heat transfer efficient microchannel design has been developed using wall features that create stable disrupted flow and break the laminar boundary layer in a microchannel over a wide range of flow rates. The paper experimentally investigates the developed design for the heat transfer enhancement and pressure drop increase compared to a smooth wall microchannel. A simple microchannel device was designed and fabricated with and without wall features. The experiments with single gas phase fluid showed promising results with the developed wall feature design as the heat transfer rate increase was 20% to 80% more than the pressure drop increase in the laminar regime. The wall feature design was an important variable to affect the magnitude of performance enhancement in different flow regime. A general criterion was developed to judge the efficacy of wall feature design that can be used during a microchannel heat exchanger design.
ChemInform Abstract: Structure, Biosynthetic Relationships and Chemical Synthesis of the Icetexane Diterpenoids (2009)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Note: Refined possibilities for plasma probe diagnostics (2016)

In an earlier publication, the ion mass determination technique was proposed using the Langmuir probe measurement results for low-pressure Maxwellian plasmas and their analysis, based on the Bohm effect and the Child-Boguslavsky-Langmuir (CBL) probe sheath model, allowing for probe sheath thickness and ion mass evaluations after the Bohm coefficient CBCyl ≈ 1.13 for cylindrical probes had been determined. In the present study, the step-front sheath model, being physically closer to the reality of gas discharge plasmas, was considered in order to correct the CBL sheath model results. At this stage, more real Bohm coefficient (CBCyl ≈ 1.23) for cylindrical probes was found to provide a more reliable method of probe sheath thickness and ion mass determination.
Two-jet differential cross section inpp¯ collisions at √s¯11.8 TeV (1990)

The two-jet differential cross section ${\mathit{d}}^{3}$\ensuremath{\sigma}(p\ifmmode\bar\else\textasciimacron\fi{}p\ensuremath{\rightarrow}jet 1+jet 2+X)/${\mathit{dE}}_{\mathit{t}}$d${\mathrm{\ensuremath{\eta}}}_{1}$d${\mathrm{\ensuremath{\eta}}}_{2}$, averaged over -0.6\ensuremath{\le}${\mathrm{\ensuremath{\eta}}}_{1}$\ensuremath{\le}0.6, at \ensuremath{\surd}s =1.8 TeV, has been measured in the Collider Detector at Fermilab. The predictions of leading-order quantum chromodynamics for most choices of structure functions show agreement with the data.
Performance degradation of PN matched filter with clock frequency offset and its compensation (1987)

Abstract One of the important problems in the spread‐spectrum communication system is the despreading of the received signal in the receiver. The CCD delay‐line matched filter is a kind of device realizing the despreading. It has a problem in that the sampling frequency must be exactly the same as the clock frequency of the spread signals contained in the received signal. When there is an offset between the two frequencies, the performance of despreading is degraded in the delay‐line matched filter. However, for this problem, no quantitative analysis has been made so far. This paper presents a theoretical analysis by the new method and under several assumptions, for the degradation of the peak output in the CCD delay‐line matched filter when there exists an offset of the clock frequency. The results are compared with the results of computer simulation. Based on these results, a CCD matched filter loop is proposed which has the function to follow the various frequency offsets. Its performance is demonstrated by the simulation.
Resolving Genetic Functions within Microbial Populations: In Situ Analyses Using rRNA and mRNA Stable Isotope Probing Coupled with Single-Cell Raman-Fluorescence In Situ Hybridization (2008)

Prokaryotes represent one-half of the living biomass on Earth, with the vast majority remaining elusive to culture and study within the laboratory. As a result, we lack a basic understanding of the functions that many species perform in the natural world. To address this issue, we developed complementary population and single-cell stable isotope ((13)C)-linked analyses to determine microbial identity and function in situ. We demonstrated that the use of rRNA/mRNA stable isotope probing (SIP) recovered the key phylogenetic and functional RNAs. This was followed by single-cell physiological analyses of these populations to determine and quantify in situ functions within an aerobic naphthalene-degrading groundwater microbial community. Using these culture-independent approaches, we identified three prokaryote species capable of naphthalene biodegradation within the groundwater system: two taxa were isolated in the laboratory (Pseudomonas fluorescens and Pseudomonas putida), whereas the third eluded culture (an Acidovorax sp.). Using parallel population and single-cell stable isotope technologies, we were able to identify an unculturable Acidovorax sp. which played the key role in naphthalene biodegradation in situ, rather than the culturable naphthalene-biodegrading Pseudomonas sp. isolated from the same groundwater. The Pseudomonas isolates actively degraded naphthalene only at naphthalene concentrations higher than 30 muM. This study demonstrated that unculturable microorganisms could play important roles in biodegradation in the ecosystem. It also showed that the combined RNA SIP-Raman-fluorescence in situ hybridization approach may be a significant tool in resolving ecology, functionality, and niche specialization within the unculturable fraction of organisms residing in the natural environment.
A prospective, randomized, double-blind study assessing the clinical impact of integrated pharmacogenomic testing for major depressive disorder. (2013)

Pharmaco-genomic-guided treatment with GeneSight doubles the likelihood of response in all patients with treatment resistant depression and identifies 30% of patients with severe gene-drug interactions who have the greatest improvement in depressive symptoms when switched to genetically suitable medication regimens.
The Fishmouth Phenomenon (1977)

&lt;p&gt;Autonomous agents negotiating on our behalf find applications in everyday life in many domains such as high frequency trading, cloud computing and the smart grid among others. The agents negotiate with one another to reach the best agreement for the users they represent. An obstacle in the future of automated negotiators is that the agent may not always have a priori information about the preferences of the user it represents. The purpose of this work is to develop an agent that will be able to negotiate given partial information about the user’s preferences. First, we present a new partial information model that is supplied to the agent, which is based on categorical data in the form of pairwise comparisons of outcomes instead of precise utility information. Using this partial information, we develop an estimation model that uses linear optimization and translates the information into utility estimates. We test our methods in a negotiation scenario based on a smart grid cooperative where agents participate in energy trade-offs. The results show that already with very limited information the model becomes accurate quickly and performs well in an actual negotiation setting. Our work provides valuable insight into how uncertainty affects an agent’s negotiation performance, how much information is needed to be able to formulate an accurate user model, and shows a capability of negotiating effectively with minimal user feedback.&lt;/p&gt;
ON THE CHROMATOGRAPHIC ISOLATION OF TWO DIFFERENT KOBER CHROMOGENS FROM PREGNANT COW'S URINE, WITH SOME REMARKS ON THE ANALYTICAL PROCEDURE (1958)

Few attempts have as yet been made in the chemical determination of oestrogenic hormones in urine from the bovine species, although many authors, by use of bioassay, have shown that considerable amounts of oestrogenic substances are excreted by this route during the last few months of pregnancy (Aschheim & Zondek, 1927, Hisaw & Meyer, 1929, Nibler & Turner, 1929 a and b, Lipschutz & Veshnjakov, 1930, Turner et al., 1930, Anderson, 1934, O'Moore, 1947). Brooks & Klyne (1953) studied lipid extracts from urines of bulls and pregnant cows, but were not able to isolate any steroids by chemical methods. Hafez (1955), using the method of Stimmel, reported isolation of minute amounts of oestrone and oestradiol in the urine of buffaloes in early pregnancy (95 to 105 days). Hafez & Attar (1956), quantitatively determined oestrogens (as oestrone) in the urine of buffaloes at various stages of pregnancy. These authors claimed to
Cyclosporin A Inhibits Monocyte Tissue Factor Activation in Cardiac Transplant Recipients (1997)

This study demonstrates that TF activation, occurring in mononuclear cells of cardiac transplant recipients, is inhibited by treatment with CsA. Inhibition of monocyte TF induction by CsA may contribute to its successful use in cardiac transplant medicine and might be useful in managing further settings of vascular pathology also known to involve TF expression and NF-kappaB activation.
Fibrinogen Zurich I: Impaired Release of Fibrinopeptide A (1979)

Fibrinogen Zurich I is characterized by an abnormal fibrin monomer polymerization. It consists of two fractions of molecules, one with a normal aggregation and one not aggregating at all and interfering with the aggregation of the normal population. Using a radioimmunoassay for fibrinopeptide A, only approximately half of the expected fibrinopeptide A could be recovered after thrombin or Defibrase proteolysis. The defective fibrinopeptide A release could be confirmed by measurement of the N-terminal Gly/Tyr ratio. It is likely that the abnormal fibrin monomer aggregation of the abnormal fraction of fibrinogen Zurich I is due to the defective fibrinopeptide A release of this fraction.
Acute hemodynamic effects of hydralazine in dogs with chronic mitral regurgitation (1985)

The hemodynamic response to hydralazine administration was evaluated in 6 conscious small dogs with chronic mitral regurgitation. All dogs underwent invasive and noninvasive hemodynamic monitoring before and after hydralazine administration. Cardiac output and pulmonary capillary wedge pressure were measured with a Swan-Ganz thermodilution catheter. Systemic arterial blood pressure (AP) was measured directly by inserting a needle into the femoral artery. Standard M-mode echocardiograms and thoracic radiographs were obtained. Other hemodynamic variables were calculated. Base-line hemodynamic variables were altered severely in all dogs. Hydralazine decreased mean arterial blood pressure from 104 +/- 18 (mean +/- SD) to 78 +/- 12 mm of Hg (P less than 0.005), total systemic resistance index from 2,946 +/- 625 to 1,261 +/- 420 dynes-s-cm-5m2 (P less than 0.005), and pulmonary capillary wedge pressure from 40 +/- 5 to 26 +/- 3 mm of Hg, (P less than 0.005). Cardiac index increased from 2.92 +/- 0.72 to 5.36 +/- 1.67 L/min/m2 of body surface area (P less than 0.005). Mixed venous oxygen tension (PvO2) increased from 28.4 +/- 4.3 to 41.2 +/- 5.2 mm of Hg (P less than 0.001). Pulmonary edema resolved, as determined on thoracic radiographs. Mixed venous oxygen tension correlated well with the cardiac index (r = 0.92; P less than 0.001). It was concluded that hydralazine administration caused a small decrease in end diastolic diameter (4.8 +/- 0.9 to 4.5 +/- 0.8 cm, P less than 0.05) and end systolic diameter (2.6 +/- 0.8 to 2.3 +/- 0.7 cm, P less than 0.05). Fractional shortening and heart rate did not change.(ABSTRACT TRUNCATED AT 250 WORDS)
Combined Measurement of Soluble ST2 and Amino-Terminal Pro-B-Type Natriuretic Peptide Provides Early Assessment of Severity in Cardiogenic Shock Complicating Acute Coronary Syndrome (2017)

The combination of results for soluble ST2 and amino-terminal pro-B-type natriuretic peptide provides early risk assessment beyond clinical variables in patients with acute coronary syndrome-related cardiogenic shock and may help therapeutic decision making in these patients.