gebhart/patrepeval huggingface dataset:
Factors Affecting Water Consumption by Holstein Cows in Early Lactation (1983)

Our objective was to examine relationships between water intake by dairy cows in early lactation and dry matter intake, milk production, sodium intake, and ambient temperature. After parturition, 19 multiparous Holstein cows were assigned randomly to one of four diets for 16 wk. Water consumption, dry matter intake, milk production, and maximum and minimum temperature were recorded daily and averaged weekly. There was no significant dietary effect on water intake, dry matter intake, or milk production; therefore, data were analyzed by stepwise multiple linear regression across diets. The final equation was: water intake (kg/day) = 15.99 + 1.58 (standard error .271) dry matter intake (kg/day) + .90 (.157) milk production (kg/day) + .05 (.023) sodium intake (g/day) + 1.20 (.106) minimum temperature (C). Coefficient of multiple determination was .59. All temperature measures (mean, minimum, maximum) were closely correlated which justified the use of only one. Dry matter intake and milk production also were correlated but out of phase. Regression coefficients for milk production and sodium intake agreed with literature estimates. Major factors determining water consumption in early lactation have been identified and quantitated.
Supplementary Data S3 from SAM-Competitive PRMT5 Inhibitor PF-06939999 Demonstrates Antitumor Activity in Splicing Dysregulated NSCLC with Decreased Liability of Drug Resistance (2023)

&lt;p&gt;ElasticNet Tables for PF-06939999 in NSCLC&lt;/p&gt;
Smart Phone Interaction with Registered Displays (2009)

This article describes the theory and practice of display registration with smart phones, findings in initial user studies, and opportunities for developing markerless display registration schemes.
Improved Dielectric Breakdown Strength of Covalently-Bonded Interface Polymer–Particle Nanocomposites (2010)

Interfacial covalent bonding is an effective approach to increase the electrical resistance of a polymer–particle composite to charge flow and dielectric breakdown. A bifunctional tether reagent bonded to an inorganic oxide particle surface assists with particle dispersion within a thermosetting epoxy polymer matrix but then also reacts covalently with the polymer matrix. Bonding the particle surface to the polymer matrix resulted in a composite that maintained the pure polymer glass transition temperature, compared to modified or unmodified particle dispersions that lacked covalent bonding to the polymer matrix, which depressed the polymer glass transition to lower temperatures. The added interfacial control, directly bonding the particle to the polymer matrix, appears to prevent conductive percolation across particle surfaces that results in a reduced Maxwell–Wagner relaxation of the polymer–particle composite and a reduced sensitivity to a dielectric breakdown event. The inclusion of 5 vol% particles of higher permittivity produces a composite of enhanced dielectric constant and, with surface modification to permit surface cross-linking into the polymer, a polymer–particle composite with a Weibull E 0 dielectric breakdown strength of 25% greater than that of the pure polymer resulted. The estimated energy density for the cross-linked interface composite was improved 260% compared to the polymer alone, 560% better than a polymer–particle composite synthesized using bare particles, and 80% better than a polymer–particle composite utilizing bare particles with a dispersant.
Application of Augmented Reality in Engineering Graphics Education (2011)

Engineering graphics (EG) is the subject of transferring information from design into manufacture. Developing ability to create and read graphical representation of engineering structure is essential for individual. Therefore, training engineers able to use the graphical language to communicate is vital in every engineering college. However, in the classroom, where lecture time is limited, it is hard for the instructors to illustrate clearly the relationship between the 3D geometry and their 2D projection using only one kind of presenting technique. This work gives a brief insight into the potential and challenges of using Augmented Reality (AR) in Engineering Graphics Education. An AR-based system specifically designed for EG instruction were studied and developed. The system aims at improving the spatial awareness and interest of learning. Our own interest is to apply the AR system to Engineering Graphics instruction and provide the students with their own unique discovery path. The AR application enables faster comprehension of complex spatial problems and relationships which will benefit the students greatly during their learning processes. The AR-based method is proved to be effective teaching aids for engineering graphics courses and applying AR technology to support learning activities may become a trend in the future.
Dry bulk freight rate to rise in 2017: : MSI (2017)

UK-based shipping consultant MSI told delegates at the Roskill's 2017 Salt conference that dry bulk freight rate will increase in 2017, but any policy change in China could cause volatility in shipping costs. UK-based shipping consultant MSI told delegates at the Roskill's 2017 Salt conference, held at the end of...
Mixed Metal Phosphonate- Phosphate Resins for Separation of Lanthanides from Actinides (2017)

As indicated in the previous annual report the goals of this project are to develop procedures for efficient separation of lanthanides from actinides and curium from americium. These processes are required for the nuclear fuel cycle to minimize the waste and recover the valuable actinides. The basis for our study is that we have prepared a group of compounds that are porous and favor the uptake of ions with charges 3+ and 4+ over ions of lesser charge. The general formula for these materials is M(O3PC6H4PO3)1-x/2(APO4)x·nH2O: where M=Zr4+, Sn4+, A=H, Na, or K and X=O, 0.5, 0.8, 1.0, 1.33 and 1.61-3. One of our tasks is to determine which members of this group of compounds are effective in carrying out the required separations. A difficulty in obtaining this required information is that the compounds are amorphous. That is they are not crystalline, therefore we need to resort to synchrotron data to obtain structural data which will be presented in detail. This information will be provided as a separate section.
A study of arc modelling in low-voltage switching devices (2017)

The motion of an arc plasma in a quenching chamber has a significant influence on the interruption performance of low-voltage switching devices (LVSDs). It is necessary to build an arc modelling tool, which can predict an arc behavior during an interruption process, to save development cost and time. This paper presents a numerical model of an arc plasma in LVSDs, which can reduce complexity and calculation load of an arc simulation by avoiding fully coupled modelling between fluid dynamics, and electromagnetism. There are two steps in the proposed arc modelling; the first is the finite element analysis of Lorentz force generated by nonlinear ferromagnetic material and current path in a quenching chamber, the second is the finite volume analysis of arc motion with consideration for fluid dynamics and heat transfer. This arc modelling also takes into account a contact motion, potential drops in the sheath layers of splitter plates and plasma radiation. It is shown that the simulated result has a similar trend with experimental data in terms of the arc motion as well as current and voltage waveforms.
An Improved Rotor Speed Observer for Standalone Brushless Doubly-Fed Induction Generator Under Unbalanced and Nonlinear Loads (2019)

The conventional control methods for brushless doubly-fed induction generator (BDFIG) normally employ mechanical sensors to acquire the information of rotor speed, which brings many disadvantages in the cost, complexity, reliability, etc. This paper presents an improved rotor speed observer (RSO) for the sensorless operation of standalone BDFIGs, which is based on the power winding (PW) voltage and control winding (CW) current. In order to eliminate the impact of unbalanced and nonlinear loads on the RSO, second-order generalized integrators (SOGIs) and low-pass filters (LPFs) are introduced to pre-filter the PW voltage and CW current, respectively. Through comprehensive parameter design, the response speed of the improved RSO will be not lower than that of the basic RSO with ensuring the filtering effect of these additional filters. In addition, the proposed RSO is independent to machine parameters except the pole pairs. Comprehensive experiments are conducted and results verify the proposed improved RSO applied to the standalone BDFIG. Also, the applicability of the proposed RSO on another dual-electrical-port machine, doubly-fed induction generator, is confirmed by simulation results.
Signaling pathways differ in pregnancy and exercise‐induced cardiac hypertrophy (2011)

Exercise- and pregnancy-induced cardiac hypertrophy are both considered beneficial and adaptive. Because previous research suggests a role for Akt and glycogen synthase kinase-3β (GSK-3β) in cardiac growth, the objective of this study was to examine the role of Akt and GSK-3β in cardiac hypertrophy resulting from pregnancy or exercise. Three-month-old female mice expressing a cardiac specific, myristolated form of Akt (myrAkt) or constitutively active form of GSK-3β (caGSK-3β) were used. Mice were divided into control, late pregnancy, and 21 days of voluntary exercise. Wild type (WT) mice had a 16% increase in heart weight-to-body weight ratio (HW/BW) in response to exercise, and pregnancy induced a 15% increase in heart weight-to-tibial length ratio (HW/TL). Although myr-Akt mice have dramatically larger hearts relative to WT mice at baseline, myr-Akt mice exhibited significant exercise-induced cardiac hypertrophy. In contrast, pregnant myr-Akt mice had a slight, but insignificant increase in HW/TL ratio. Hearts from control caGSK-3β mice were smaller compared to control WT, and were not blocked in exercise-induced hypertrophy. However, pregnant caGSK-3β mice had attenuated cardiac growth compared to pregnant WT (8%, p<0.05). Thus, we conclude that both Akt and GSK3β are critical mediators of pregnancy-induced cardiac hypertrophy, but not essential in exercise-induced cardiac hypertrophy.
Meningococcal biofilm formation: structure, development and phenotypes in a standardized continuous flow system (2006)

We show that in a standardized in vitro flow system unencapsulated variants of genetically diverse lineages of Neisseria meningitidis formed biofilms, that could be maintained for more than 96 h. Biofilm cells were resistant to penicillin, but not to rifampin or ciprofloxacin. For some strains, microcolony formation within biofilms was observed. Microcolony formation in strain MC58 depended on a functional copy of the pilE gene encoding the pilus subunit pilin, and was associated with twitching of cells. Nevertheless, unpiliated pilE mutants formed biofilms showing that attachment and accumulation of cells did not depend on pilus expression. Mutation and complementation analysis revealed that the type IV pilus-associated protein PilX, which was recently shown to mediate interbacterial aggregation, indirectly supported microcolony formation by contributing to pilus expression. A large number of PilX alleles was identified among genetically diverse meningococcal strains. PilX alleles differed in their propensity to support autoaggregation of cells in suspension, but not in their ability to support microcolony formation within biofilms in the continuous flow system.
Molecule–molecule and atom–molecule collisions with ultracold RbCs molecules (2021)

Abstract Understanding ultracold collisions involving molecules is of fundamental importance for current experiments, where inelastic collisions typically limit the lifetime of molecular ensembles in optical traps. Here we present a broad study of optically trapped ultracold RbCs molecules in collisions with one another, in reactive collisions with Rb atoms, and in nonreactive collisions with Cs atoms. For experiments with RbCs alone, we show that by modulating the intensity of the optical trap, such that the molecules spend 75% of each modulation cycle in the dark, we partially suppress collisional loss of the molecules. This is evidence for optical excitation of molecule pairs mediated via sticky collisions. We find that the suppression is less effective for molecules not prepared in the spin-stretched hyperfine ground state. This may be due either to longer lifetimes for complexes in the dark or to laser-free decay pathways. For atom–molecule mixtures, RbCs + Rb and RbCs + Cs, we demonstrate that the rate of collisional loss of molecules scales linearly with the density of atoms. This indicates that, in both cases, the loss of molecules is rate-limited by two-body atom–molecule processes. For both mixtures, we measure loss rates that are below the thermally averaged universal limit.
Adaptive Clutter Density in Multi-Hypothesis Tracking. (2011)

In underwater surveillance active sonar is an important technological asset. Compared to passive sonar it features higher detection ranges and enables the detection of silent objects. As a drawback the interaction of sound waves with the seabed and the water surface causes false alarms, named clutter. False alarms usually appear randomly and variable in time and space. To distinguish false alarms from true contacts the Multi-Hypothesis Tracking approach can be used. This approach incorporates the density of sonar contacts to extract possible target tracks. Thus, the assumed clutter density influences, amongst others, the performance of this tracking approach. This paper presents a method for determining the clutter density adaptively. It considers positions of all sonar contacts within one measurement and thereby approximates the actual clutter density precisely. The influence on the tracking results using adaptive clutter density in a multi-hypothesis tracker is shown by applying the algorithm to two multistatic sonar datasets and comparing it to results obtained by tracking using constant clutter density. Tracking performance is quantified by existing tracking performance metrics.
Pharmacokinetics of Human Immunodeficiency Virus Protease Inhibitor, Nelfinavir, in Poloxamer 407-Induced Hyperlipidemic Model Rats (2009)

The effect of hyperlipidemia (HL) on the pharmacokinetics of nelfinavir (NFV), a human immunodeficiency virus protease inhibitor, was investigated, focusing on the change of NFV distribution in plasma using poloxamer 407-induced HL model rats (HL rats). The plasma unbound fraction (f(u)) in HL rats (0.20-0.39%) was significantly lower than the control (0.92-1.47%). Lipoprotein level in HL rats was about 5 times higher and low- and very low-density liproteins ratio were 1.7-4.5 times higher than the control. NFV recovery in the triglyceride-rich lipoprotein such as chylomicron, low- and very low-density liproteins fractions of HL rats were significantly higher. The area under the plasma concentration-time curve (AUC) of NFV after intravenous (i.v.: 5 mg/kg) and intraduodenal (i.d.: 30 mg/kg) administration to HL rats (i.v.: 6.12+/-0.48, i.d.: 24.4+/-2.2 microg x h/ml) were higher than the control (i.v.: 1.62+/-0.21, i.d.: 5.00+/-0.36 microg x h/ml). The steady state volume of distribution (Vd(ss)) in HL rats (0.60+/-0.07 l/kg) was lower than the control (6.25+/-0.55 l/kg). Systemic availability (F) in HL rats (66.6%) was higher than the control (51.4 %). Directly absorbed NFV from the gastrointestinal tract to the lymphatic system in HL rats was about 2 times higher than the control. From the results of this study, it was concluded that the increase of AUC was caused by decreasing f(u) and Vd(ss) due to the increase of the triglyceride-rich lipoprotein level. In addition, it was suggested that the increase of absorbed NFV through the lymphatic system, which did not receive the first-pass effect, was one reason for the increase of F in HL rats.
T cell activation is attenuated in transgenic mice rich in omega-3 fatty acids (P6227) (2013)

Abstract Cytokines such as interleukin (IL)-4, IL-5 and IL-13 mainly produced by CD4+ type 2 helper T lymphocytes (Th2 cells) have an important role in pathophysiology of allergic airway inflammation. Therefore, modulation of Th2 cells may offer a novel therapeutic approach to control allergic asthma. It has been suggested that n-3 PUFA can be used as preventive or therapeutic strategy to control allergic asthma. However, mechanisms by which n-3 PUFA modulates this disease are not fully understood. Here, the effects of elevated n-3 PUFA on OVA-induced airway inflammation were investigated using Fat-1 transgenic mice which can convert n-6 PUFA to n-3 PUFA endogenously. First, this study tested whether Fat-1 expression modulates CD4+ T cell activation, proliferation, and differentiation in vitro and found that Fat-1 expression attenuated all of these CD4+ T cell responses. When Fat-1 mice were sensitized and challenged with OVA, these mice showed significantly reduced inflammatory cell recruitment into airway, lower levels of Th2 cytokines, mucin production and eotaxin in brochoalveolar lavage (BAL) and lung tissues. OVA-specific IgE were also significantly lower in Fat-1 mice. Furthermore, suppressed CD4+ T cell activation and differentiation were also observed in Fat-1 mice. Taken together, these results demonstrate that elevated n-3 PUFA play a protective role in airway inflammation by modulating CD4+ T cell activation and differentiation in Fat-1 mice.
An Epitope Chimeric Antigen for the Hepatitis C Virus Serological Screening Test. (1996)

The epitope chimeric antigen, CepCM, composed of the 9 selected major epitope regions (two in NS3, two each in the NS4 of two genotypes, two each in the core of two genotype, and one in the core in hepatitis C virus (HCV) polypeptide), was expressed as a fusion protein of the trpE peptide in E. coli. An ELISA test using this antigen produced the same judgements with most of the panel sera as a second generation HCV screening kit. Though discrepancies were found in twelve samples (5% of the samples), further analysis revealed that eleven samples were indeterminate sera as judged by an immunoblot test. The reactivity found in several seroconversion series sera suggested that CepCM has superior reactivity to HCV infected sera than some second generation kits. These data indicated that an epitope chimeric antigen with a man-made sequence will be a excellent tool for a diagnostic test kit.
Im2Avatar: Colorful 3D Reconstruction from a Single Image (2018)

Existing works on single-image 3D reconstruction mainly focus on shape recovery. In this work, we study a new problem, that is, simultaneously recovering 3D shape and surface color from a single image, namely "colorful 3D reconstruction". This problem is both challenging and intriguing because the ability to infer textured 3D model from a single image is at the core of visual understanding. Here, we propose an end-to-end trainable framework, Colorful Voxel Network (CVN), to tackle this problem. Conditioned on a single 2D input, CVN learns to decompose shape and surface color information of a 3D object into a 3D shape branch and a surface color branch, respectively. Specifically, for the shape recovery, we generate a shape volume with the state of its voxels indicating occupancy. For the surface color recovery, we combine the strength of appearance hallucination and geometric projection by concurrently learning a regressed color volume and a 2D-to-3D flow volume, which are then fused into a blended color volume. The final textured 3D model is obtained by sampling color from the blended color volume at the positions of occupied voxels in the shape volume. To handle the severe sparse volume representations, a novel loss function, Mean Squared False Cross-Entropy Loss (MSFCEL), is designed. Extensive experiments demonstrate that our approach achieves significant improvement over baselines, and shows great generalization across diverse object categories and arbitrary viewpoints.
Pathologic and Clinical Spectrum of Post-Thymic T-Cell Malignancies (1984)

(1984). Pathologic and Clinical Spectrum of Post-Thymic T-Cell Malignancies. Cancer Investigation: Vol. 2, No. 5, pp. 413-426.
ChemInform Abstract: A One‐Pot Synthesis of Functionalized 2,2‐Disubstituted 2H‐1‐Benzopyrans. (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Cross-refractive chiral media and constitutive contrasts (1999)

The concept of cross-refractive chiral media is proposed, and the plane-wave response of a planar interface between two such media is determined. The proposed concept—along with the related concepts of isoimpedant and isorefractive chiral chiral media—completes a study on constitutive contrasts between two isotropic chiral media. ©1999 John Wiley & Sons, Inc. Microwave Opt Technol Lett 20: 337–339, 1999.
Inducible Knockout Strategies to Probe the Functions of 5‐HT Receptorsa (1998)

Gene targeting has proven to be extremely powerful in various fields of biological research. Through this technique, knockout mice lacking a particular gene and thus a particular protein, can be generated. One limitation to this technique is the fact that mice develop without the protein of interest and therefore, developmental compensations may have taken place, contributing to an observed phenotype. Inducible strategies, those which allow the timing of expression of a gene to be regulated, are currently being developed and should prove useful when applied to gene targeting technology. In order to begin to apply such new technologies to the field of gene targeting, we first created and tested several reporter constructions using the tetracycline inducible system. Here we describe the creation of several beta-galactosidase reporter constructions and the results of in vitro testing in Cos-7 cells. We then discuss future knockout strategies based upon our observations.
Central Nervous System Depressants. I. 1-Aminoalkyl-3-aryl Derivatives of 2-Imidazolidinone,1a-c 2-Imidazolidinethione, and Tetrahydro-2(1H)-pyrimidinone1d (1966)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCentral Nervous System Depressants. I. 1-Aminoalkyl-3-aryl Derivatives of 2-Imidazolidinone,1a-c 2-Imidazolidinethione, and Tetrahydro-2(1H)-pyrimidinone1dWilliam B. Wright Jr., Herbert J. Brabander, Robert A. Hardy Jr., and Arnold C. OsterbergCite this: J. Med. Chem. 1966, 9, 6, 852–857Publication Date (Print):November 1, 1966Publication History Published online1 May 2002Published inissue 1 November 1966https://pubs.acs.org/doi/10.1021/jm00324a017https://doi.org/10.1021/jm00324a017research-articleACS PublicationsRequest reuse permissionsArticle Views387Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts