gebhart/patrepeval huggingface dataset:
Fast Transient Response of Series Resonant Converters Using Average Geometric Control (2015)

Linear controllers and small-signal modeling techniques have been used for over 40 years to control power electronic converters around the equilibrium operating point. Outside the quiescent area, the shortcomings of linear controllers are well known and include uncertain large-signal transient behavior and sluggish dynamic/recovery response. In particular, resonant converters have inherent large-signal behavior, making the transient performance of small-signal linear controllers poor. This paper develops a geometric controller based on large-signal modeling to achieve enhanced dynamic response of the series resonant converter (SRC). The proposed modeling strategy provides detailed insight into the behavior of the SRC and creates an analytical framework to successfully perform geometric control. A new geometric control law is mathematically derived using average circular trajectories producing accurate and fast dynamics during startup, sudden load or reference changes. In order to validate the theoretical analysis, experimental and simulation results of an SRC are presented and compared to those of a linear and a nonlinear controller. The dynamic response is, on average, over 100 times faster than that of the designed linear controller, while overshoot is virtually eliminated.
Positive Modulators of theN-Methyl-d-aspartate Receptor: Structure–Activity Relationship Study of Steroidal 3-Hemiesters (2018)

Here, we report the synthesis of pregn-5-ene and androst-5-ene dicarboxylic acid esters and explore the structure-activity relationship (SAR) for their modulation of N-methyl-d-aspartate receptors (NMDARs). All compounds were positive modulators of recombinant GluN1/GluN2B receptors (EC<sub>50</sub> varying from 1.8 to 151.4 μM and E<sub>max</sub> varying from 48% to 452%). Moreover, 10 compounds were found to be more potent GluN1/GluN2B receptor modulators than endogenous pregnenolone sulfate (EC<sub>50</sub> = 21.7 μM). The SAR study revealed a relationship between the length of the residues at carbon C-3 of the steroid molecule and the positive modulatory effect at GluN1/GluN2B receptors for various D-ring modifications. A selected compound, 20-oxo-pregnenolone hemiadipate, potentiated native NMDARs to a similar extent as GluN1/GluN2A-D receptors and inhibited AMPARs and GABA<sub>A</sub>R responses. These results provide a unique opportunity for the development of new steroid based drugs with potential use in the treatment of neuropsychiatric disorders involving hypofunction of NMDARs.
Hydraulic Modeling of Fish Screens (1993)

Hydraulic model studies coupled with available knowledge of fish behavior can be important component in the development of fish-screening systems. To reproduce in a model the flow field through and around a fish screen, the model screen must have the same headloss coefficient as the prototype screen. A series of tests is currently being conducted at IIHR to obtain headloss coefficients for various fish screen configurations. The screen include perforated plates, bar screens, and combinations of perforated plates and bar screens at various angles with the flow. The paper gives a summary of the results obtained to date.
Computers and Information Systems (1984)

Computers and information systems , Computers and information systems , مرکز فناوری اطلاعات و اطلاع رسانی کشاورزی
Liquid Crystal Dispersions (2020)

Dispersions of liquid crystals in a solid polymer matrix have improved and expanded the performance of liquid crystals in a variety of applications. Dispersions of cholesteric liquid crystals were first used as temperature indicators to improve their ease of use and environmental stability. Two liquid crystal dispersion technologies have been extensively researched. Liquid crystals have been encapsulated in a polymer film by microencapsulation or emulsification techniques and are generically termed nematic curvilinear aligned phase. The Off state scattering is maximized by using liquid crystals with large birefringence and droplet sizes on the order of visible wavelengths and a high density of droplets. Electro-optic materials that switch from a scattering to a transparent state have been made from mixtures consisting of nematic liquid crystals dispersed in polymer microspheres connected by a small quantity of binder. The gap between the microspheres is filled with nematic liquid crystals.
Computer-controlled two-color laser-based optical stimulator for vision research (1991)

A two-color laser-based stimulator is described. This device produces high intensity uniform field illumination with temporal control over a wide range of temporal frequencies. In addition it can be used to produce wide field flicker (40 degrees ).
Superconducting and microstructural properties of [001] tilt YBa/sub 2/Cu/sub 3/O/sub 7-δ/ thick film grain boundaries on SrTiO/sub 3/ bicrystal substrates (2001)

We present a study of superconducting and microstructural properties of [001] tilt YBa/sub 2/Cu/sub 3/O/sub 7-/spl delta// (YBCO) thick film grain boundaries (GB) on SrTiO/sub 3/ bicrystal substrates prepared using a BaF/sub 2/ ex-situ post deposition reaction process. For a 15/spl deg/ tilt boundary, multiple microbridges were patterned across the grain boundary at various locations. A large variation of local critical current density J/sub c/ was observed. Through local microstructural characterization of these GB bridges using transmission electron microscopy (TEM), a direct correlation of local GB J/sub c/ with structure is identified.
A Comparison of 400nm and 800nm Femtosecond laser Pulses in Dissociative Ionization of Ethanol (2005)

Role of the center wavelength of excitation laser pulses on dissociative ionization of ethanol is studied using 400 nm and 800 nm femtosecond laser pulses. Contribution of multi-photon excitation increases with 400 nm laser pulses.
A Single Input Multiple Output (SIMO) Variation-Tolerant Nanosensor (2018)

Successful transition to commercialization and practical implementation of nanotechnology innovations may very well need device designs that are tolerant to the inherent variations and imperfections in all nanomaterials including carbon nanotubes, graphene, and others. As an example, a single-walled carbon nanotube network based gas sensor is promising for a wide range of applications such as environment, industry, and biomedical and wearable devices due to its high sensitivity, fast response, and low power consumption. However, a long-standing issue has been the production of extremely high purity semiconducting nanotubes, thereby contributing to the delay in the market adoption of those sensors. Inclusion of even less than 0.1% of metallic nanotubes, which is inevitable, is found to result in a significant deterioration of sensor-to-sensor uniformity. Acknowledging the coexistence of metallic and semiconducting nanotubes as well as all other possible imperfections, we herein present a novel variation-tolerant sensor design where the sensor response is defined by a statistical Gaussian measure in contrast to a traditional deterministic approach. The single input and multiple output data are attained using multiport electrodes fabricated over a relatively large area single nanotube ensemble. The data processing protocol discards outlier data points and the origin of the outliers is investigated. Both the experimental demonstration and complementary analytical modeling support the hypothesis that the statistical analysis of the device can strengthen the credibility of the sensor constructed using nanomaterials with any imperfections. The proposed strategy can also be applied to physical, radiation, and biosensors as well as other electronic devices.
Properties of acrylic bone cement: State of the art review (1997)

Acrylic bone cement occupies a distinctive place in the hierarchy of synthetic biomaterials, because it is the only material currently used for anchoring the prosthesis to the contiguous bone in a cemented arthroplasty. However, the cement is not without its drawbacks. The main one is the role that it has been postulated to play in the aseptic loosening and, hence, clinical life of the arthroplasty. In turn, this role is directly related to the mechanical properties of the cement, especially the resistance to fracture of the cement in the mantle at the cement-prosthesis interface or the cement-bone interface. The present work is a detailed critical review of the recent literature on the properties of bone cement that are considered germane to its use in the stated application. The relevant properties are identified and a case is made for including each of them. Compilations of the values of these properties, obtained under clearly identified conditions, are presented for the six commercial formulations of bone cement in current popular orthopedic use. The gaps and unresolved questions in the current data base, efforts that should be made to address these issues, and research directions are covered.
Time encoding of LPC roots (2005)

A time encoding scheme of the center frequencies of the LPC inverse filter roots is presented. The roots are represented in terms of center frequency (CF) and bandwidth (BW), and the continuity of the CF's in time is established by a dynamic programming scheme which has a cost function depending on both CFs and BWs. Segmentation points are set at the beginning or end of root tracks, at the voiced-unvoiced transitions and at the peaks of a function measuring the dissimilarity of adjacent frames. The tracks within segments are then fitted by linear combinations of orthogonal polynomials. Without quantization, the processed speech is subjectively indistinguishable from the original synthetic speech. Good quality is achieved even below 1000 bps.
Hepatic Knockdown of RECK Increases NASH Susceptibility (2019)

Introduction Nonalcoholic steatohepatitis (NASH) is characterized by hepatic steatosis, hepatocellular inflammation and fibrosis. Reversion‐inducing‐cysteine‐rich protein with Kazal motifs (RECK) exerts anti‐fibrotic effects in the heart, although its role in NASH is unknown. We have previously shown that western diet (WD)‐induced NASH and fibrosis were associated with RECK downregulation in the liver. Here, we examined whether RECK knockdown, specifically in liver, increases NASH susceptibility. Methods Homozygous RECK floxed mice on a C57/BL6J background were injected with either an AAV8‐TBG‐Cre (1×10 12 ) ( RECK‐KD ) for liver‐specific knockdown of RECK or an AAV8‐TBG‐GFP control ( RECK‐CON ). Following AAV injections, mice ( n = 5–8) were fed either a control diet (CD; 10% fat) or WD (45% fat, 17% sucrose) for 8 weeks. An additional set of mice injected with AAV8‐TBG‐Cre or AAV8‐TBG‐GFP were fed WD for 30 weeks ( n = 8). Results After 8 weeks, WD feeding significantly increased body weight and body fat percentage vs CD (p≤0.05). There were no differences in animal characteristics between RECK‐KD and RECK‐CON in either CD or WD groups. Nonalcoholic fatty liver disease activity score (NAS; combination of steatosis, ballooning, and inflammation) was significantly elevated in WD vs CD fed mice (p&lt;0.05), with further exacerbation with RECK‐KD for NAS and inflammation scores (main effect for genotype, p&lt;0.05). Furthermore, RECK‐KD mice had a ~3‐fold increase in hepatic fibrosis compared to RECK‐CON (main effect for genotype, p≤0.05). Thirty weeks of WD feeding significantly elevated NAS (p&lt;0.01) and fibrosis scores (P&lt;0.01) compared with 8 weeks of WD feeding. In addition, RECK knockdown exacerbated NAS (p&lt;0.05), inflammation score (p=0.001), and fibrosis (p=0.06) compared to RECK‐CON mice following 30 weeks of WD feeding. Further investigations revealed that RECK‐KD (vs. RECK‐CON ) expressed significantly higher IKK‐β gene expression (p&lt;0.05), along with trends for increases in hepatic inflammatory markers NF‐κB, TGF‐β, and JUN at 30 weeks. Expression of matrix metalloproteases‐2 and −14 also tended to be elevated in RECK‐KD mice (vs RECK‐CON) at 30 weeks. Conclusion Here we demonstrate for the first time that liver‐specific RECK knockdown exacerbates western diet induced NASH. Further investigation is warranted to determine the role and precise mechanisms by which RECK regulates hepatocellular inflammation and NASH progression. Support or Funding Information VA Merit Grant I01BX003271‐01 (R.S.R.), VA Merit Grant I01BX004220‐01 (B.C.) This abstract is from the Experimental Biology 2019 Meeting. There is no full text article associated with this abstract published in The FASEB Journal .
Aplicabilidade do método magnetotelúrico em área de cobertura carbonática – estudo de caso na Serra do Mel, Bacia Potiguar (2009)

PreviousNext No Access11th International Congress of the Brazilian Geophysical Society & EXPOGEF 2009, Salvador, Bahia, Brazil, 24-28 August 2009Aplicabilidade do método magnetotelúrico em área de cobertura carbonática – estudo de caso na Serra do Mel, Bacia PotiguarAuthors: Paulo T.L. MenezesAndrea ZerilliTiziano LabruzzoPaulo T.L. Menezes(Petrobras-E&P-EXP/GEOF/MP), Andrea ZerilliWesternGeco EM, and Tiziano LabruzzoWesternGeco EMhttps://doi.org/10.1190/sbgf2009-105 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Abstract This paper is in Portuguese. In the present paper we present the results of a MT field campaign at Potiguar basin. The main objectives of this survey were to test the MT signal to noise ratio and the feasibility of the MT data to define the base of Jandaíra Formation (shallow carbonates) and the structural framework of the basement. To that end, MT data of 17 remote reference sites were processed and investigated through tensor analysis decomposition followed by 1D inversion. Three main geoeletrical units were identified: an outcropping strong resistor associated to Barreiras sandstones, followed by the carbonates of Jandaíra Fm and a strong conductor at depth, associated to siliciclastic sediments. The top of the basement was also properly imaged as a strong resistor underlying the sedimentary sequence. Keywords: magnetotelluric, carbonates, 1D, inversionPermalink: https://doi.org/10.1190/sbgf2009-105FiguresReferencesRelatedDetails 11th International Congress of the Brazilian Geophysical Society & EXPOGEF 2009, Salvador, Bahia, Brazil, 24-28 August 2009ISSN (online):2159-6832Copyright: 2009 Pages: 1997 publication data© 2009 Published in electronic format with permission by the Brazilian Geophysical SocietyPublisher:Society of Exploration Geophysicists HistoryPublished Online: 28 Apr 2014 CITATION INFORMATION Paulo T.L. Menezes, Andrea Zerilli, and Tiziano Labruzzo, (2009), "Aplicabilidade do método magnetotelúrico em área de cobertura carbonática – estudo de caso na Serra do Mel, Bacia Potiguar," SEG Global Meeting Abstracts : 466-471. https://doi.org/10.1190/sbgf2009-105 Plain-Language Summary Keywordsmagnetotelluriccarbonates1DinversionPDF DownloadLoading ...
The Level of Expression of the Minor Pilin Subunit, CooD, Determines the Number of CS1 Pili Assembled on the Cell Surface of Escherichia coli (1999)

CooD, the minor subunit of CS1 pili of enterotoxigenic Escherichia coli, is essential for the assembly of stable, functional pili. We previously proposed that CooD is a rate-limiting initiator of CS1 pilus assembly and predicted that the level of CooD expression should therefore determine the number of CS1 pili assembled on the cell surface. In this study, we confirm that CooD is required for the initiation of pilus assembly rather than for the stabilization of pili after they are assembled by demonstrating that specific modulation of cooD expression also modulates the number of CS1 pili on bacterial cells.
Piezoelectric Templates – New Views on Biomineralization and Biomimetics (2016)

Biomineralization in general is based on electrostatic interactions and molecular recognition of organic and inorganic phases. These principles of biomineralization have also been utilized and transferred to bio-inspired synthesis of functional materials during the past decades. Proteins involved in both, biomineralization and bio-inspired processes, are often piezoelectric due to their dipolar character hinting to the impact of a template's piezoelectricity on mineralization processes. However, the piezoelectric contribution on the mineralization process and especially the interaction of organic and inorganic phases is hardly considered so far. We herein report the successful use of the intrinsic piezoelectric properties of tobacco mosaic virus (TMV) to synthesize piezoelectric ZnO. Such films show a two-fold increase of the piezoelectric coefficient up to 7.2 pm V(-1) compared to films synthesized on non-piezoelectric templates. By utilizing the intrinsic piezoelectricity of a biotemplate, we thus established a novel synthesis pathway towards functional materials, which sheds light on the whole field of biomimetics. The obtained results are of even broader and general interest since they are providing a new, more comprehensive insight into the mechanisms involved into biomineralization in living nature.
Monte Carlo simulation of multiphoton fluorescence microscopic imaging through inhomogeneous tissuelike turbid media (2003)

Image resolution and signal level in fluorescence microscopy through inhomogeneous turbid media consisting of scatterers of multiple sizes under single- (1p), two- (2p), and three-photon (3p) excitation have been investigated based on a modified Monte Carlo model. The effects of the size distribution and the concentration distribution of scattering particles are explored. Simulation results reveal that the size and the concentration distribution both have an impact on image formation in media consisting of small particles and that 3p excitation has the most significant impact. In media with scatterers of a large size, both size and concentration distributions lead to a slight effect. Image formation in a mixed medium containing small and large scattering particles is more affected by the large particles.
Real-time measurements of atmospheric CO using a continuous-wave room temperature quantum cascade laser based spectrometer (2012)

A compact, mobile mid-infrared laser spectrometer based on a thermoelectrically (TE) cooled continuous-wave room temperature quantum cascade laser and TE-cooled detectors has been newly developed to demonstrate the applicability of high sensitivity and high precision measurements of atmospheric CO. Performance of the instrument was examined with periodic measurements of reference sample and ambient air at 1 Hz sampling rate and a 1-hourly calibration cycle. The typical precision evaluated from replicate measurements of reference sample over the course of 66-h is 1.41 ppbv. With the utilization of wavelet filtering to improve the spectral SNR and minimize the dispersion of concentration values, a better precision of 0.88 ppbv and a lower detection limit of ~0.4 ppbv with sub-second averaging time have been achieved without reducing the fast temporal response. Allan variance analysis indicates a CO measurement precision of ~0.28 ppbv for optimal integration time of approximate 50 s. The absolute accuracy is limited by the calibration gas standard. This completely thermoelectrically cooled system shows the capability of long-term, unattended and continuous operation at room temperature without complicated cryogenic cooling.
Laboratory measurements of radon diffusion through multilayered cover systems for uranium tailings (1981)

Laboratory measurements of radon fluxes and radon concentration profiles were conducted to characterize the effectiveness of multilayer cover systems for uranium tailings. The cover systems utilized soil and clay materials from proposed disposal sites for the Vitro, Durango, Shiprock, Grand Junction and Riverton tailings piles. Measured radon fluxes were in reasonable agreement with values predicted by multilayer diffusion theory. Results obtained by using air-filled porosities in the diffusion calculations were similar to those obtained by using total porosities. Measured diffusion coefficients were a better basis for predicting radon fluxes than were correlations of diffusion coefficient with moisture or with air porosity. Radon concentration profiles were also fitted by equations for multilayer diffusion in the air-filled space. Layer-order effects in the multilayer cover systems were examined and estimated to amount to 10 to 20 percent for the systems tested. Quality control measurements in support of the multilayer diffusion tests indicated that moisture absorption was not a significant problem in radon flux sampling with charcoal canisters, but that the geometry of the sampler was critical. The geometric design of flux-can samplers was also shown to be important. Enhanced radon diffusion along the walls of the test columns was examined and was found to be insignificant except when the columns had been physically disturbed. Additional moisture injected into two test columns decreased the radon flux, as expected, but appeared to migrate into surrounding materials or to be lost by evaporation. Control of moisture content and compaction in the test columns appeared to be the critical item affecting the accuracies of the experiments.
Megapixel detector arrays: visible to 28 μm (2004)

Large infrared detector arrays are now available that meet the demanding requirements of the astronomy and civil space communities. This paper describes arrays with more than one million detector elements developed by Raytheon Vision Systems for these low-background applications. These detector arrays have 1024 x 1024 and 2048 x 2048 formats with element spacing ranging from 20 to 27 &mu;m. Arrays of this size have been demonstrated with a variety of deteector materials: Si PIN, HgCdTe, InSb, and Si:As IBC. The performance of each of these materials on arrays with more than one million detector elements is discussed. All of these detector materials have demonstrated low noise and dark current, high quantum efficiency, and excellent uniformity. All can meet the high performance requirements for low-background within the limits of their respective spectral and operating temperature ranges. Features of the readout integrated circuits that mate to these detector arrays are also discussed. Companion papers in these SPIE proceedings that discuss several of these arrays in more detail are: 1. "Large-format 0.85 and 2.5 &mu;m HgCdTe detctor arrays for low-background applications", P.J. Love, A. W. Hoffman, D. L. Gulbransen, K. J. Ando, M. P. Murray, N. J. Therrien 2. "James Webb Space Telescope characaterization of flight candidate NIR InSb array", C. W. McMurtry, W. J. Forrest, J. L. Pipher, A. C. Moore 3. "Orion II: the second-generation readout multiplexer for largest infrared hybrid focal plane", K. M. Merrill, A. M. Fowler, W. Ball, A. Henden, F. J. Vrba, C. McCreight 4. "Interpixel capacitance in nondestructive focal plane arrays" A. C. Moore 5. "Radiation environment performance of JWST prototype FPAs", M. E. McKelvey, K. A. Enico, R. E. McMurray Jr., R. A. Reed, C. R. McCreight 6. "Independent testing of JWST detector prototypes," D. F. Figer, B. Rauscher, M. W. Regan, J. Balleza, L. Bergeron, E. Morse, H. S. Stockman.