gebhart/patrepeval huggingface dataset:
Self-Organization of Polystyrenes into Ordered Microstructured Films and Their Replication by Soft Lithography (2005)

We report on the formation of ordered arrays of micrometric holes on the surface of polystyrene (PS) films cast from volatile solvents in the presence of humidity at different temperatures. The formation mechanism is investigated for PS having different molecular weights, polydispersities, and carboxylic terminations. Among the chosen materials, a highly regular honeycomb microstructured morphology is obtained on the surface of films prepared with dicarboxy-terminated PS with <molecular weight> = 100,000. Experiments and observations on film formation indicate that polar groups are playing a fundamental role in this process. Tuning the surface tension by means of polar terminations allows the film morphology to be modified and in particular the preparation of two- or three-dimensional microstructured films. Finally, we show how these structures can be replicated by soft lithography and then used in the fields of photonic crystals and organic electronics.
Protein Status in Pancreatitis – Transthyretin Is a Sensitive Biomarker of Malnutrition in Acute and Chronic Pancreatitis (2002)

Malnutrition may develop in acute pancreatitis (AP), accompanied by hypermetabolism and high nutritional requirements, and in chronic pancreatitis (CP). We measured the incidence of protein malnutrition in AP and CP by comparing different serum biomarkers of protein metabolism and inflammation. Thirty-five patients with acute (27 moderate, 8 severe), and 35 with chronic, pancreatitis were enrolled in the study. Serum transthyretin, albumin, transferrin and C-reactive protein (CRP) concentrations were measured in AP at admission, after 1 and 2 weeks of jejunal feeding, and in patients with CP at follow-up. In AP, at admission the transthyretin level was low in 74%, transferrin in 48%, and albumin in 29% of patients. In severe pancreatitis, transthyretin levels were significantly lower than in moderate forms (7.5 +/- 2.43 vs. 14.39 +/- 6.8 mg/dl, p < 0.005). Transthyretin levels increased significantly after 2 weeks of jejunal feeding (p < 0.05). In CP, transthyretin levels were decreased in 37%, transferrin in 27%, and albumin in 12% of patients. We found significantly lower transthyretin levels in alcohol-related CPthan in other forms (18.5 +/- 8.3 vs. 30.2 +/- 5.7, p < 0.01). Transthyretin correlated positively with albumin and transferrin and negatively with CRP Transthyretin seems to be a sensitive biomarker of protein status and metabolic stress. Monitoring nutritional status through measurement of serum proteins is important for optimal treatment of AP and CP.
Transient increase of fractional anisotropy in reversible vasogenic edema (2016)

Brain vasogenic edema, involving disruption of the blood-brain barrier, is a common pathological condition in several neurological diseases, with a heterogeneous prognosis. It is sometimes reversible, as in posterior reversible encephalopathy syndrome, but often irreversible and our current clinical tools are insufficient to reveal its reversibility. Here, we show that increased fractional anisotropy in magnetic resonance imaging is associated with the reversibility of vasogenic edema. Spontaneously, hypertensive rats-stroke prone demonstrated posterior reversible encephalopathy syndrome-like acute encephalopathy in response to high-dose cyclosporine A treatment; the deteriorating neurological symptoms and worsening scores in behavioral tests, which were seen in acute phase, dissappered after recovery by cessation of cyclosporine A. In the acute phase of encephalopathy, the fractional anisotropy and apparent diffusion coefficient increased in areas with IgG leakage. This increase of fractional anisotropy occurred in the absence of demyelination: fluid leakage into the myelinated space increased the axial, but not the radial, diffusivity, resulting in the increased fractional anisotropy. This increased fractional anisotropy returned to pre-encephalopathy values in the recovery phase. Our results highlight the importance of the fractional anisotropy increase as a marker for the reversibility of brain edema, which can delineate the brain areas for which recovery is possible.
Effect of fluorine concentration on the etch characteristics of fluorinated tetraethylorthosilicate films (1996)

Fluorinated silicon dioxide films have generated much interest as potential low dielectric constant materials for use in back end interconnect technologies in microelectronics manufacturing. A recent article from this group reported on the reliability and stability of fluorinated oxide films. These films were prepared in a conventional parallel plate dual frequency plasma-enhanced chemical-vapor deposition reactor. The concentration of the fluorine in the film was varied by changing the deposition parameters. The highest fluorine concentration obtained was 15% in that study. The fluorine included in the film is expected to affect the results obtained during plasma etch of the film. The effect of the incorporated fluorine on the etch rate of the film and microloading and the profile of contact structures are examined.
Computing the Heat of Adsorption using Molecular Simulations: The Effect of Strong Coulombic Interactions (2008)

Molecular simulations are an important tool for the study of adsorption of hydrocarbons in nanoporous materials such as zeolites. The heat of adsorption is an important thermodynamic quantity that can be measured both in experiments and molecular simulations, and therefore it is often used to investigate the quality of a force field for a certain guest-host (g - h) system. In molecular simulations, the heat of adsorption in zeolites is often computed using either of the following methods: (1) using the Clausius-Clapeyron equation, which requires the partial derivative of the pressure with respect to temperature at constant loading, (2) using the energy difference between the host with and without a single guest molecule present, and (3) from energy/particle fluctuations in the grand-canonical ensemble. To calculate the heat of adsorption from experiments (besides direct calorimetry), only the first method is usually applicable. Although the computation of the heat of adsorption is straightforward for all-silica zeolites, severe difficulties arise when applying the conventional methods to systems with nonframework cations present. The reason for this is that these nonframework cations have very strong Coulombic interactions with the zeolite. We will present an alternative method based on biased interactions of guest molecules that suffers less from these difficulties. This method requires only a single simulation of the host structure. In addition, we will review some of the other important issues concerning the handling of these strong Coulombic interactions in simulating the adsorption of guest molecules. It turns out that the recently proposed Wolf method ( J. Chem. Phys. 1999, 110 , 8254 ) performs poorly for zeolites as a large cutoff radius is needed for convergence.
A Cleavable C2-Symmetric trans-Cyclooctene Enables Fast and Complete Bioorthogonal Disassembly of Molecular Probes (2020)

Bioorthogonal chemistry is bridging the divide between static chemical connectivity and the dynamic physiologic regulation of molecular state, enabling in situ transformations that drive multiple technologies. In spite of maturing mechanistic understanding and new bioorthogonal bond-cleavage reactions, the broader goal of molecular ON/OFF control has been limited by the inability of existing systems to achieve both fast (i.e., seconds to minutes, not hours) and complete (i.e., >99%) cleavage. To attain the stringent performance characteristics needed for high fidelity molecular inactivation, we have designed and synthesized a new C<sub>2</sub>-symmetric <i>trans</i>-cyclooctene linker (C<sub>2</sub>TCO) that exhibits excellent biological stability and can be rapidly and completely cleaved with functionalized alkyl-, aryl-, and H-tetrazines, irrespective of click orientation. By incorporation of C<sub>2</sub>TCO into fluorescent molecular probes, we demonstrate highly efficient extracellular and intracellular bioorthogonal disassembly via omnidirectional tetrazine-triggered cleavage.
GC [gas chromatography]/MS [mass spectroscopy]/computers (1972)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGC [gas chromatography]/MS [mass spectroscopy]/computersFrancis W. KarasekCite this: Anal. Chem. 1972, 44, 4, 32A–42aPublication Date (Print):April 1, 1972Publication History Published online21 September 2008Published inissue 1 April 1972https://pubs.acs.org/doi/10.1021/ac60312a053https://doi.org/10.1021/ac60312a053research-articleACS PublicationsRequest reuse permissionsArticle Views149Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Kalman-Filter-Based Tracking of Millimeter-Wave Channel Parameters for V2X Applications (2019)

The spectrum of millimeter waves, when properly exploited, represents an important asset for achieving the high data rates and low latencies required by applications in vehicular communications. However, vehicle scenarios are characterized by high mobility, which results in frequent misalignment of beams. Therefore, in these types of scenarios, beam tracking algorithms are important because they can keep the beams aligned with a low training overhead. Kalman filters are strong candidates for the implementation of such algorithms, because they ensure high channel tracking performance over a wide range of signal-to-noise-ratios (SNR) and are easy to implement. This work evaluates the performance of channel tracking methods based on Kalman filters for high mobility. Our numerical results show that the proposed Kalman filter-based channel tracking method has high performance at low SNR regimes compared to least square-based methods, and improve the robustness when using planar instead of linear arrays. Moreover, the proposed channel tracking method is shown to perform well in multipath fading scenarios, while achieving high performance in the presence of strong line-of-sight components.
Crosstalk between Lysosomes and Mitochondria in Parkinson's Disease (2017)

Parkinson's disease (PD) is the most common motor neurodegenerative disorder. In most cases the cause of the disease is unknown, while in about 10% of subjects, it is associated with mutations in a number of different genes. Several different mutations in 15 genes have been identified as causing familial forms of the disease, while many others have been identified as risk factors. A striking number of these genes are either involved in the regulation of mitochondrial function or of endo-lysosomal pathways. Mutations affecting one of these two pathways are often coupled with defects in the other pathway, suggesting a crosstalk between them. Moreover, PD-linked mutations in genes encoding proteins with other functions are frequently associated with defects in mitochondrial and/or autophagy/lysosomal function as a secondary effect. Even toxins that impair mitochondrial function and cause parkinsonian phenotypes, such as rotenone, also impair lysosomal function. In this review, we explore the reciprocal relationship between mitochondrial and lysosomal pathways in PD. We will discuss the impact of mitochondrial dysfunction on the lysosomal compartment and of endo-lysosomal defects on mitochondrial function, and explore the roles of both causative genes and genes that are risk factors for PD. Understanding the pathways that govern these interactions should help to define a framework to understand the roles and mechanisms of mitochondrial and lysosomal miscommunication in the pathophysiology of PD.
Serum Neopterin and Somatization in Women with Chemical Intolerance, Depressives, and Normals (1998)

The symptom of intolerance to low levels of environmental chemicals (CI, chemical intolerance) is a feature of several controversial polysymptomatic conditions that overlap symptomatically with depression and somatization, i.e., chronic fatigue syndrome, fibromyalgia, multiple chemical sensitivity, and Persian Gulf syndrome. These syndromes can involve many somatic symptoms consistent with possible inflammation. Immunological or neurogenic triggering might account for such inflammation. Serum neopterin, which has an inverse relationship with l-tryptophan availability, may offer a marker of inflammation and macrophage/monocyte activation. This study compared middle-aged women with CI (who had high levels of affective distress; n = 14), depressives without CI (n = 10), and normals (n = 11). Groups did not differ in 4 p.m. resting levels of serum neopterin. However, the CI alone had strong positive correlations between neopterin and all of the scales measuring somatization. These preliminary findings suggest the need for additional research on biological correlates of 'unexplained' multiple somatic symptoms in subtypes of apparent somatizing disorders.
Anisotropic holographic scattering in centrosymmetric sodium nitroprusside (1999)

Anisotropic holographic light scattering has been discovered in centrosymmetric single crystals of sodiumnitroprusside, Na2[Fe(CN)5NO]⋅2H2O, in which the photorefractive response is based on the excitation of metastable electronic states. Besides a bright homogeneous scattering corona generated by isotropic scattering, a sharp scattering ring builds up with light polarized orthogonal to that of the pump beam and the corona. This anisotropic scattering resulting from interference of scattered waves with the pump beam occurs although there is no linear electro-optic effect in centrosymmetric crystals.
Imaging Block-Selective Copolymer Solvation (2023)

Understanding individual-block solvation in self-assembled block copolymer systems is experimentally difficult, but this solvation underpins the assembly and disassembly observed at the bulk scale. Here, covalently attached viscosity-sensitive molecular rotors for fluorescence lifetime imaging microscopy uncover and quantitatively elucidate previously undisclosed differential block-selective responses toward solvation changes upon addition of DMSO and THF to self-assembled ROMP-based amphiphilic block copolymers. The sensitivity of this method provides unique information on block-selective solvent-triggered assembly and disassembly mechanisms, revealing behaviors invisible to or with superior sensitivity to traditional <sup>1</sup>H NMR spectroscopy. These experiments demonstrate an analytical method and provide a granular mechanistic understanding, both suitable for fine tuning block copolymer assembly and disassembly processes.
Orbital hydrodynamics of the anisotropic a phase of 3He for large angles of rotation of the orbital momentum (1977)

A linear hydrodynamic theory of the orbital order parameter rotations and mass transport in the A phase of superfluid 3He is proposed which is free of the problems related to the definition of the phase ϕ, and thus, to describe large angle rotations of the order parameter orbital symmetry axis Î, is simpler and more adequate than the locally equivalent theory of Graham.
Applications of games to propositional proof complexity (2008)

In this thesis we explore a number of ways in which combinatorial games can be used to help prove results in the area of propositional proof complexity. The results in this thesis can be divided into two sets, the first being dedicated to the study of Resolution space (memory) requirements, whereas the second is centered on formalizing the notion of `dangerous&apos; reductions. The first group of results investigate Resolution space measures by asking questions of the form, `Given a formula F and integer k, does F have a [Type of Resolution] proof with [Type of Resource] at most k?&apos;. We refer to this as a proof complexity resource problem, and provide comprehensive results for several forms of Resolution as well as various resources. These results include the PSPACE-Completeness of Tree Resolution clause space (and the Prover/Delayer game), the PSPACE-Completeness of Input Resolution derivation total space, and the PSPACE-Hardness of Resolution variable space. This research has theoretical as well as practical motivations: Proof complexity research has focused on the size of proofs, and Resolution space requirements are an interesting new theoretical area of study. In more practical terms, the Resolution proof system forms the underpinnings of all modern SAT-solving algorithms, including clause learning. In practice, the limiting factor on these algorithms is memory space, so there is a strong motivation for better understanding it as a resource. With the second group of results in this thesis we investigate and formalize what it means for a reduction to be `dangerous&apos;. The area of SAT-solving necessarily employs reductions in order to translate from other domains to SAT, where the power of highly-optimized algorithms can be brought to bear. Researchers have empirically observed that it is unfortunately possible for reductions to map easy instances from the input domain to hard SAT instances. We develop a non-Hamiltonicity proof system and combine it with additional results concerning the Prover/Delayer game from the first part of this thesis as well as proof complexity results for intuitionistic logic in order to provide the first formal examples of harmful and beneficial reductions, ultimately leading to the development of a framework for studying and comparing translations from one language to another.
Coordinated Investigation of Cystic Astrocytomas by Nuclear Medicine and Neuroradiological Techniques (1975)

Astrocytomas are the most common intracranial neoplasm in children. It is necessary to demonstrate preoperatively the location and extent of a possible neoplastic cyst and to differentiate it from the part that is solid. This is achieved through brain scans, computer axial tomography and angiography. Though of considerable help, brain scan and computer axial tomography are insufficient in providing the neurosurgeon with the complete character and geography of the neoplasm necessary for successful surgical treatment. Demonstration of these features can only be elucidated by contrast angiography. Consequently, the coordination of these three techniques permits the precise evaluation of the presence, nature, and operative and postoperative course of cystic astrocytomas.
Health‐related quality of life in early Parkinson's disease: The impact of nonmotor symptoms (2013)

Nonmotor symptoms (NMS) are common in patients with established Parkinson's disease (PD) and have a major impact upon quality of life. We investigated the significance of NMS in relation to health-related quality of life (HRQoL) in patients with newly diagnosed PD. Patients and healthy controls were recruited as part of the Incidence of Cognitive Impairment in Cohorts with Longitudinal Evaluation in Parkinson's Disease Study. Prevalence of NMS was determined with the Non-Motor Symptom Questionnaire. HRQoL was recorded with the 39-item Parkinson's Disease Quality of Life Questionnaire (PDQ-39). Further assessments included measures of motor disability, depression, sleep, and cognition. One hundred and fifty-eight patients with newly diagnosed PD and 99 controls participated in this cross-sectional study. Patients reported greater numbers of NMS than controls (mean 8.3 ± 4.3 versus 2.8 ± 2.5 symptoms; P < 0.001). Patients reported lowest HRQoL in the domains assessing bodily discomfort, mobility, and activities of daily living. Motor and nonmotor symptoms impacted negatively upon HRQoL scores. Patients with the postural instability and gait difficulty motor subtype reported worse HRQoL, compared with those with tremor-dominant disease. Depression (P < 0.001), incomplete bowel emptying (P < 0.001), anxiety (P < 0.001), impaired concentration (P < 0.001), memory complaints (P < 0.001), and insomnia (P = 0.001) had the greatest negative impact upon HRQoL. NMS are common in patients with early PD and represent a significant cause of poorer health-related quality of life. Cognitive, neuropsychiatric, and sleep disturbances are particularly associated with reduced well-being. Screening and management of these symptoms should be prioritized at the time of diagnosis.
Identification of an alternative form of human lactoferrin mRNA that is expressed differentially in normal tissues and tumor-derived cell lines (1997)

Lactoferrin (LF), traditionally known as an iron-binding protein present in high concentrations in milk and various secretions, has emerged as a multifunctional protein involved in many aspects of the host defense against infection. Recently, LF has been shown to inhibit the growth of solid tumors and reduce experimental metastasis in mice, suggesting that LF also may play a role in the defense against tumorigenesis. Here we provide the sequence of the cDNA and promoter region, the chromosome assignment, and tissue expression pattern of a novel form of LF mRNA (delta LF). The sequence of delta LF mRNA is nearly identical to that of LF mRNA; however, at the 5' end, we find a novel sequence that replaces the N-terminal signal peptide sequence of LF mRNA. We map the delta LF mRNA to human chromosome 3 and find that both delta LF and LF sequences colocalize to the same cloned 90- to 150-kb genomic DNA fragment. We further show that the delta LF mRNA is the product of alternative splicing of the LF gene and likely is specified by use of an alternative promoter. Although we find delta LF mRNA at various levels in 20 of 20 adult and fetal human tissues, we do not find delta LF mRNA in any of 14 diverse tumor-derived cell lines.
[Preparation of monoclonal antibodies against West Nile virus envelope protein domain.]. (2006)

The results of indirect ELISA, Western blot and indirect immunofluorescence experiment indicated that these three McAbs were specific for West Nile virus envelope protein domain and did not cross-react with Japanese encephalitis virus and other viruses, so they can be used for specific detection of West Nile virus.
The Time Gap Between Pd-103 Prostate Brachytherapy and Supplemental Beam Radiation Does Not Impact on Rectal Morbidity or Likelihood of Cure (2008)

Shorter gap intervals between supplemental beam radiation and brachytherapy implant are safe. Shorter gap intervals do not improve BFFS; however, they do allow for treatment completion in a more timely fashion.
Evidence for improved control of hypertension in Taiwan: 1993–2002 (2008)

There was a significant improvement of hypertension awareness, treatment, and control in the TwSHHH survey compared with the NAHSIT survey in Taiwan.
Packing variations on a ripple of nearly monodisperse dry sand (2010)

Dielectric measurements reveal that bulk density on the surface of recently mobilized dry ripples of a nearly monodisperse desert sand varies from the random jammed packing at troughs to the minimum value for a stable packing at crests, suggesting that active ripples are relatively loose structures moving above a more consolidated substratum. Although the wind‐driven evolution of static pressure on the surface induces air seepage through sand, we show that such internal flow is not strong enough to swell the bed and explain variations of bulk density on the surface.