gebhart/patrepeval huggingface dataset:
Who's #1? (2012)

A website's ranking on Google can spell the difference between success and failure for a new business. NCAA football ratings determine which schools get to play for the big money in postseason bowl games. Product ratings influence everything from the clothes we wear to the movies we select on Netflix. Ratings and rankings are everywhere, but how exactly do they work? Who's #1? offers an engaging and accessible account of how scientific rating and ranking methods are created and applied to a variety of uses. Amy Langville and Carl Meyer provide the first comprehensive overview of the mathematical algorithms and methods used to rate and rank sports teams, political candidates, products, Web pages, and more. In a series of interesting asides, Langville and Meyer provide fascinating insights into the ingenious contributions of many of the field's pioneers. They survey and compare the different methods employed today, showing why their strengths and weaknesses depend on the underlying goal, and explaining why and when a given method should be considered. Langville and Meyer also describe what can and can't be expected from the most widely used systems. The science of rating and ranking touches virtually every facet of our lives, and now you don't need to be an expert to understand how it really works. Who's #1? is the definitive introduction to the subject. It features easy-to-understand examples and interesting trivia and historical facts, and much of the required mathematics is included.
Anti-Mullerian hormone expression pattern in the human ovary: potential implications for initial and cyclic follicle recruitment (2004)

Anti-Müllerian hormone (AMH) is a member of the transforming growth factor-beta superfamily, which plays an important role in both ovarian primordial follicle recruitment and dominant follicle selection in mice. However, the role of AMH in folliculogenesis in humans has not been investigated in detail. In the present study, AMH expression was assessed using immunohistochemistry in ovarian sections, obtained from healthy regularly cycling women. To this end, a novel monoclonal antibody to human AMH was developed. AMH expression was not observed in primordial follicles, whereas 74% of the primary follicles showed at least a weak signal in the granulosa cells. The highest level of AMH expression was present in the granulosa cells of secondary, preantral and small antral follicles <or=4 mm in diameter. In larger (4-8 mm) antral follicles, AMH expression gradually disappeared. In conclusion, in the human AMH expression follows a similar pattern as compared to the mouse and rat, suggesting an important role of AMH in folliculogenesis.
Recombinant osteogenic protein‐1 upregulates extracellular matrix metabolism by rabbit annulus fibrosus and nucleus pulposus cells cultured in alginate beads (2003)

This study was performed to determine if recombinant human osteogenic protein-1 (rhOP-1) is effective in promoting matrix synthesis and matrix formation by rabbit nucleus pulposus (NP) and annulus fibrosus (AF) cells cultured in alginate beads. The effects of culturing the cells in the presence of various concentrations of rhOP-1 were assessed by measuring changes in cell proliferation, proteoglycan (PG) and collagen synthesis and mRNA expression, and in the matrix contents of PG and collagen, as indicators of matrix accumulation. At high concentrations, rhOP-1 had a moderate mitogenic effect on both NP and AF cells. It also stimulated the synthesis of PG and collagen in a dose-dependent manner: this was associated with a corresponding increase in the expression of mRNA for aggrecan core protein and collagen type II. The stimulatory effect of rhOP-1 on PG synthesis was more pronounced than that on collagen synthesis. Continuous treatment with rhOP-1 led to an increase in the total DNA, PG and collagen contents in both NP and AF cultures. The results presented here provide evidence of the ability of rhOP-1 to stimulate the metabolism of both rabbit AF and NP cells cultured in alginate beads.
Coupling Deterministic and Monte Carlo Transport Methods for the Simulation of Gamma-Ray Spectroscopy Scenarios (2008)

Simulation is often used to predict the response of gamma-ray spectrometers in technology viability and comparative studies for homeland and national security scenarios. Candidate radiation transport methods generally fall into one of two broad categories: stochastic (Monte Carlo) and deterministic. Monte Carlo methods are the most heavily used in the detection community and are particularly effective for calculating pulse-height spectra in instruments. However, computational times for scattering- and attenuation-dominated problems can be extremely long - many hours or more on a typical desktop computer. Deterministic codes that discretize the transport in space, angle, and energy offer potential advantages in computational efficiency for these same kinds of problems, but pulse-height calculations are not readily accessible. This paper investigates a method for coupling angular flux data produced by a three-dimensional deterministic code to a Monte Carlo model of a gamma-ray spectrometer. Techniques used to mitigate ray effects, a potential source of inaccuracy in deterministic field calculations, are described. Strengths and limitations of the coupled methods, as compared to purely Monte Carlo simulations, are highlighted using example gamma-ray detection problems and two metrics: (1) accuracy when compared to empirical data and (2) computational time on a typical desktop computer.
ChemInform Abstract: A Metathesis Reaction Route to Obtain Fine Mg2Si Particles. (2014)

Abstract Mg 2 Si particles with diameters less than 1 μm are prepared by a solid state metathesis reaction of NaSi, MgCl 2 , and Na (BN crucible, 650 °C, 10 h).
Can Multipath TCP be Robust to Cyber Attacks With Incomplete Information? (2020)

Promoted by the advancements in the various wireless access technologies, modern mobile devices equipped with multiple network interfaces are rapidly becoming the norm, and this provides a driving force for the large-scale deployment of the Multipath Transmission Control Protocol (MPTCP) in the current and future Internet. However, the simultaneous use of multiple network paths for concurrent multipath data transmission can make MPTCP have a larger attack surface than the traditional single-path transport protocols, and this may be likely to pose a risk of MPTCP being much more susceptible to cyber attacks. In this paper, we present a measurement method to investigate the vulnerability and robustness of MPTCP under cyber attacks with incomplete network information, by considering the fact that most cyber attacks normally lack of real-time information with respect to various MPTCP attributes. We mathematically characterize cyber attacks with incomplete network information from the viewpoints of both the cyber attacker and the MPTCP communication system, and then we introduce a mixed attack strategy, by jointly considering the features of both the random attacks and the selective attacks, to evaluate the robustness of MPTCP.
A role for IL-1 receptor antagonist or other cytokines in the acute therapeutic effects of IVIg? (2006)

The exact mechanism of action of IVIg in the amelioration of immune thrombocytopenic purpura (ITP) is still unclear. Studies have suggested that IVIg may function through the regulation of cytokines, including interleukin-1 receptor antagonist (IL-1Ra), an inhibitor of phagocytosis. Using a mouse model relevant to ITP, we confirm an increase in mouse serum levels of IL-1Ra after exposure to IVIg, yet a recombinant IL-1Ra did not ameliorate thrombocytopenia. IVIg has also been shown to affect the expression of other regulatory cytokines. We have also recently established that IVIg specifically targets activating FcgammaRs on CD11c+ dendritic cells (DCs) as its primary mechanism of action in the amelioration of murine ITP. Herein, we show that IVIg functions therapeutically in mice lacking specific cytokines or their receptors that can potentially affect DC/macrophage function (IL-1 receptor, IL-4, IL-10, IL-12beta, TNF-alpha, IFN-gamma receptor, MIP-1alpha). This suggests that while IVIg may mediate the release of a variety of cytokines, the cytokines tested do not directly participate in the mechanism of IVIg action.
Dual wide-band four-unit MIMO antenna system for 4G/LTE and WLAN mobile phone applications (2013)

A compact planar multiband four-unit multiple-input multiple-output (MIMO) antenna system with high isolation is developed. At VSWR ≤ 2.75, the proposed MIMO antenna operates in the frequency range of LTE Band-1, 2, 3, 7, 40 and WLAN 2.4 GHz band. A T-strip and dumbbell shaped slots are studied to mitigate mutual coupling effects. The measured worst case isolation is better that 15.3 dB and envelope correlation coefficient is less than 0.01. The received signals satisfy the equal power gain condition and radiation patterns confirm the pattern diversity to combat multipath fading effects. At 29 dB SNR, the achieved MIMO channel capacity is about 22.2 b/s/Hz. These results infer that the proposed MIMO antenna is an attractive candidate for 4G-LTE mobile phone applications.
Communication. Improved precision in inductively coupled plasma atomic-emission spectrometry by a parameter-related internal standard method (1984)

M. H. Ramsey and M. Thompson, Analyst, 1984, 109, 1625 DOI: 10.1039/AN9840901625
Enhancing the signal-to-noise ratio of ICA-based extracted ERPs (2006)

When decomposing single trial electroencephalography it is a challenge to incorporate prior physiological knowledge. Here, we develop a method that uses prior information about the phase-locking property of event-related potentials in a regularization framework to bias a blind source separation algorithm toward an improved separation of single-trial phase-locked responses in terms of an increased signal-to-noise ratio. In particular, we suggest a transformation of the data, using weighted average of the single trial and trial-averaged response, that redirects the focus of source separation methods onto the subspace of event-related potentials. The practical benefit with respect to an improved separation of such components from ongoing background activity and extraneous noise is first illustrated on artificial data and finally verified in a real-world application of extracting single-trial somatosensory evoked potentials from multichannel EEG-recordings.
A Note on the Optimality of Balanced Truncation for a Class of Infinite Dimensional Systems (2023)

Balanced truncation is a widespread model reduction method that uses balanced realizations for finite dimensional systems. The latter are state space realizations where the controllability and observability gramians are equal to the same diagonal positive matrix. In this paper, a generalization of balanced realization for a class of infinite dimensional LTI systems is employed to perform balanced truncation. It is shown that balanced truncation is optimal in the Hilbert-Schmidt sense if a particular time-varying balanced realization is used for the original LTI system. It appears that the use of time-varying balanced realizations to study the optimality and perform balanced model reduction for LTI systems is novel.
Expression of theEscherichia colichromosomalarsoperon (1996)

A chromosomally located operon (ars) of Escherichia coli has been previously shown to be functional in arsenic detoxification. DNA sequencing revealed three open reading frames homologous to the arsR, arsB, and arsC open reading frames of plasmid-based arsenic resistance operons isolated from both E. coli and staphylococcal species. To examine the outline of transcriptional regulation of the chromosomal ars operon, several transcriptional fusions, using the luciferase-encoding luxAB genes of Vibrio harveyi, were constructed. Measurement of the expression of these gene fusions demonstrated that the operon was rapidly induced by sodium arsenite and negatively regulated by the trans-acting arsR gene product. Northern blotting and primer extension analyses revealed that the chromosomal ars operon is most likely transcribed as a single mRNA of approximately 2100 nucleotides in length and processed into two smaller mRNA products in a manner similar to that found in the E. coli R773 plasmid-borne ars operon. However, transcription was found to initiate at a position that is relatively further upstream of the initiation codon of the arsR coding sequence than that determined for the E. coli R773 plasmid's ars operon.
Sequential prefetch strategies for instructions and data (1977)

An investigation of sequential prefetch as a means of reducing the average access time is conducted. The use of a target instruction buffer is shown to enhance the performance of instruction prefetch. The concept of generalized sequentiality is developed to enable the study of sequentiality in data streams. Generalized sequentiality is shown to be present to a significant degree in data streams from measurements on representative programs. This results is utilized to develop a data prefetch mechanism which is found to be capable of anticipating, on the average, about 75% of all data requests.
Charge‐remote fragmentation of bile acids derivatized with amino‐sulphonic acids (1993)

Abstract Negative‐ion fast‐atom bombardment mass spectra of free and conjugated bile acids are dominated by [M  H]− pseudomolecularions. Collision‐induced dissociations of these pseudomolecular ions give charge‐remote fragmentation patterns which are useful for structural identification. Taurine (2‐aminoethanesulrtionic acid)‐conjugated bile acids have a high cross‐section for charge‐remote fragmentation, and give the most informative and intense spectra among the naturally occurring bile acids. In the present study, collision‐induced dissociation spectra of bile acids derivatized with different aliphatic and aromatic aminosulphonates, and with 2‐amlnoethyl hydrogen sulphate have been compared. All show charge‐remote fragmentation patterns. Determination of the intensities of the fragment ions shows that the highest sensitivity is usually obtained with aromatic aininosulpho‐nate derivatives.
Comportements thermomécaniques de polymères chargés selon différents chemins de déformation et traitements thermiques (2009)

The ArcelorMittal research centre of Montataire elaborates innovative steel / polymer products. In the case of automotive fenders, the composite is a multilayered material. A thin impact polypropylene film is laminated on steel using a thin layer of a functionalized polypropylene. Mineral particles are added to improve stiffness. In order to predict and understand the behaviour of the organic layer all along its production process and finally to be able to characterize the state of its mechanical properties in use, the determination of the true and intrinsic mechanical behaviour laws according to the G'sell and Jonas model is necessary. These laws are obtained for three different mechanical paths: uniaxial tensile, simple shear and plane tensile. The deformation micromechanisms of the impact polypropylene semi-crystalline microstructure which depend on the materials formulations and on the mechanical path used are studied. Post Mortem and In Situ results give qualitative and quantitative description of the main microstructural modifications. Two new methods, X Tomography and Raman spectroscopy allow the quantification of the volume deformation which is developed during tensile tests. They are mainly available for very thin samples. X radiography and VideoTraction are not suitable anymore for this kind of geometry. Finally, the thermo-mechanical phenomenon of shrinkage which occurs during thermal treatment above the material melting point is analysed. Influences of the heating conditions, of the material formulations and of the material microstructure are described. Special overviews are done on the macromolecular chains orientation and on the volume damage influences
μ-XANES Evidence for the Reduction of Sb(V) to Sb(III) in Soil from Sb Mine Tailing (2010)

The aim of this study was to determine the mechanism of Sb immobilization occurring under reductive soil conditions. In this work, we investigated the distribution and speciation of Sb in reductive soil formed in Sb mine tailing by micro-X-ray absorption near edge structure spectroscopy (micro-XANES) and electron probe microanalyzer (EPMA). EPMA and Fe K-edge micro-XANES analyses of the soil grains indicated that Sb in soil was strongly associated with Fe(III) hydroxides secondarily formed during sedimentation. The Sb concentrations in Sb hot-spot were found to be as high as 10-30 wt % (as Sb(2)O(5)). We also found quartz particles coated by secondary rims bearing Fe(III) hydroxides and Sb. The Sb K-edge micro-XANES analyses of the rims showed that a significant amount of Sb(III) was present only at the surfaces of the rims (thickness <10 microm), indicating that Sb reduction occurred in the reducing soil. The facts suggest that the reduction to Sb(III) in the system can be an important factor for Sb immobilization under reducing conditions, since the Sb(III) sorbs more strongly on Fe(III) hydroxides than Sb(V) and its solubility is also much lower than that of Sb(V) species.
Fms-Like Tyrosine Kinase 3-Ligand Contributes to the Development and Function of the Subpopulation of CD8α+ Plasmacytoid Precursor Dendritic Cells in CD8+/TCR− Facilitating Cells (2018)

Facilitating cells (FC) are a CD8<sup>+</sup> TCR<sup>-</sup> bone marrow subpopulation that enhance engraftment of purified hematopoietic stem cells (HSC) and induce antigen-specific CD4<sup>+</sup> CD25<sup>+</sup> FoxP3<sup>+</sup> regulatory T cell (Treg) in vivo. The major subpopulation in FC resembles plasmacytoid precursor dendritic cells (p-preDC) both phenotypically and functionally. Here, we report that the number of FC was significantly reduced in Fms-like tyrosine kinase 3-ligand-knockout (Flt3-L-KO) mice. Specifically, there was a selective decrease in the B220<sup>+</sup> CD11c<sup>+</sup> CD11b<sup>-</sup> p-preDC FC subpopulation. The p-preDC FC subpopulation in FC total is restored after Flt3-L administration to Flt3-L-KO mice. FC from Flt3-L-KO donors exhibit impaired facilitation of allogeneic HSC engraftment in ablatively conditioned mice (B6 → NOD) as well as in mice conditioned with reduced intensity conditioning (B6 → BALB/c). In addition, the number of CD4<sup>+</sup> CD25<sup>+</sup> Foxp3<sup>+</sup> Treg from Flt3-L-KO mice is significantly decreased. This was associated with the expression of chemokine receptor CXCR3<sup>+</sup> or CCR5<sup>+</sup> on Treg. Treg from the spleen of Flt3-L-KO mice showed impaired facilitation of engraftment of allogeneic HSC compared to wild-type Treg. Flt3-L treatment significantly expanded Treg, and restored their facilitating function. These results suggest that Flt3-L is an important growth factor in the development and homeostasis of p-preDC FC and in the role of FC inducing generation of Treg. Flt3-L provides potent immunoregulatory properties that may be clinically useful to improve tolerance induction and enhance the function of allogeneic cell therapies. Stem Cells 2018;36:1567-1577.
Single-Step LRET Aptasensor for Rapid Mycotoxin Detection (2017)

Contamination of foods by mycotoxins is a common yet serious problem. Owing to the increase in consumption of fresh produce, consumers have become aware of food safety issues caused by mycotoxins. Therefore, rapid and sensitive mycotoxin detection is in great demand in fields such as food safety and public health. Here we report a single-step luminescence resonance energy transfer (LRET) aptasensor for mycotoxin detection. To accomplish the single-step sensor, our sensor was constructed by linking a quencher-labeled aptamer through a linker to the surface of upconversion nanoparticles (UCNPs). Our LRET aptasensor is composed of Mn<sup>2+</sup>-doped NaYF<sub>4</sub>:Yb<sup>3+</sup>,Er<sup>3+</sup> UCNPs as the LRET donor, and black hole quencher 3 (BHQ3) as the acceptor. The maximum quenching efficiency is obtained by modulating the linker length, which controls the distance between the quencher and the UCNPs. Our distinctive design of LRET aptasensor allows detection of mycotoxins selectively in colored food samples within 10 min without multiple bioassay steps. We believe our single-step aptasensor has a significant potential for on-site detection of food contaminants, environmental pollutants, and biological metabolites.
Australian smoke-charged vortex observations above New Zealand (2022)

&amp;lt;p&amp;gt;The Australian bushfires of 2019/20 caused a massive injection of combustion products into the stratosphere that led to a persistent planetary-scale perturbation of all stratospheric climate-relevant variables. This extreme event enabled study of a striking atmospheric phenomenon, the smoke-charged vortex (SCV) &amp;amp;#8211; a persistent synoptic-scale anticyclone, which acts to confine the carbon-rich aerosol clouds during their solar-driven rise. This way, highly-concentrated absorbing aerosols are lofted above 30 km, which prolongs their stratospheric residence time and radiative effects.&amp;amp;#160; Here, we use lidar observations at Lauder, New Zealand together with high-resolution radiosonde data and ozone soundings as well as satellite observations (CALIPSO, MLS, TROPOMI) and ERA5 reanalysis to characterize the optical, chemical and thermodynamical properties of a matured 7-km-tall SCV during its transfer over the South Island at 27 km altitude. The gaseous composition of the SCV was characterized by strongly enhanced water vapour and depleted ozone concentrations, leading to a synoptic-scale ozone hole with the total column reduced by up to 20%. The lidar measurements reveal a characteristic bottom-side elongation of the smoke bubble &amp;amp;#8211; a tail of aerosols extending over hundreds of kilometers and rotating together with the main body.&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;&amp;amp;#160;Using long-term ground-based lidar and satellite measurement records, we show that monthly-mean stratospheric aerosol optical depth in early 2020 was highest since the major eruption of Mt. Pinatubo in 1991. With that, the removal of smoke aerosol from the stratosphere took longer than one year.&amp;amp;#160;&amp;amp;#160;&amp;lt;/p&amp;gt;
A Template‐Based Electrochemical Method for the Synthesis of Multisegmented Metallic Nanotubes (2005)

Bimetallic nanotubes: Uniform arrays of metal nanotubes were prepared by the electrodeposition of a thin metallic film on the pore walls of anodic aluminum oxide membranes decorated with metallic nanoparticles. Multisegmented nanotubes with a bimetallic stacking configuration along the nanotube axis can be fabricated (see picture). The technique is applicable to a wide variety of conducting and semiconducting materials. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2005/z501341_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.