gebhart/patrepeval huggingface dataset:
Energy efficiency in an integrated agro-ecosystem within an acidic soil area of the Mekong Delta, Vietnam (2020)

Abstract Background Both exergy and energy analysis methodologies are used for analysing energy efficiencies in various processes, including agriculture. This study focuses on the connection of three main process components (husbandry-crop-fishpond) in a typical farming household located within an acid soil region of rural Vietnam. The concept of exergy analysis is used to underline the potential for resource efficiency in alternative processes in the agricultural system. For development of an integrated ecological system aiming towards zero emissions, the analytical methods of material cycles and energy flows utilized a set of indicators of resource efficiency in a sustainable agriculture. Results The design of the ideal integrated farming system “Agro-Industrial Zero Emissions Systems” (AIZES) can increase the system efficiency by making use of indigenous natural materials and waste reuse/recycling. Recycling waste produce energy, fish feed and fertilizer can result in a decreased environmental load of approximately half. Using exergy analysis to calculate an indicator non-renewable yield ratio (NRYR), the systems verified sustainability of agriculture production. Conclusions The farming household will be able to subsidize their fuel and electricity consumption by utilizing biogas. Surplus biogas will be distributed to proximate households, further creating sustainable goals. Biochar, created by mixing the biomass residues with local plants, will improve soil quality and pig sludge, mixed with biomass residue, will create high-quality fertilizer.
CADASIL: a genetic model of arteriolar degeneration, white matter injury and dementia in later life (2009)

Cerebral microvascular disease, as seen on magnetic resonance imaging (MRI) is common in the elderly (de Leeuw et al.,2000) and there is growing evidence that it makes a major contribution to cognitive impairment and dementia in the elderly, especially in the presence of fibrillar amyloid and tau pathology (Bennett et al., 1992, 1994; Snowdon, 1997; Snowdon et al., 2000; White et al., 2002) Understanding the unique impact of cerebral microvascular disease on cognition in the elderly is challenging because the base rate of Alzheimer's disease (AD) is high in this age group (Alzheimer's Association, 2007) making it difficult to reliably exclude patients with concomitant AD (Jellinger, 2002).
Assessment of the nonlinearity tolerance of different modulation schemes for millimeter-wave fiber-radio systems using MZ modulators (1997)

The nonlinearity tolerance of several higher order modulation schemes, which make efficient use of transmission bandwidth, such as 8-PSK, 16-QAM, and 64-QAM, has been assessed for millimeter-wave fiber-radio systems using a Mach-Zehnder (MZ) modulator for the modulation of an optical carrier. Some other deteriorating factors, such as a bias-point shift in the MZ modulator and optical carrier leakage at the MZ filter, which is used for the separation of the two optical carriers, have also been considered. The assessment was accomplished through computer simulations. It is found that the effect of the nonlinearity of the MZ modulator is less serious for a system using 8-PSK than for a system using 16-QAM or 64-QAM, and that in the latter case, an optimal drive level exists for the modulator to achieve the best system performance. A bias-point shift, required in some deployment scenarios, degrades system performance significantly. A leakage of optical carrier to the wrong port at the MZ filter further degrades the system performance, especially for systems using the 16-QAM or 64-QAM modulation scheme.
Degradation rate of poly(oxyethylene) in water by ozone. (1981)

The degradation rate of water-soluble poly(oxyethylene) (PEG) was studied under the condition of chemical reaction rate controlling, using a bubble column of 0.05 m I.D. and 0.6 m high. The degradation rate of PEG, of which initial viscosity-average molecular weight is 32, 000, is a function of viscosity-average molecular weight, dissolved ozone concentration and OH- concentration. The activation energy of the reaction is found to be 6.2 × 104 J ⋅ mol-1. An empirical equation of the degradation rate of PEG is obtained in the range of pH=5.5-8.1. The mechanism of the ozonation was studied on the basis of IR and NMR spectrochemical analysis, and a degradation scheme of PEG is proposed.
Activity of tick antimicrobial peptide from Ixodes persulcatus (persulcatusin) against cell membranes of drug-resistant Staphylococcus aureus (2016)

Persulcatusin (IP), which is an antimicrobial peptide found in Ixodes persulcatus midgut, is active against Gram-positive bacteria such as Staphylococcus aureus. Multidrug-resistant bacteria in particular methicillin-resistant S. aureus (MRSA), vancomycin-intermediate S. aureus (VISA) and vancomycin-resistant S. aureus (VRSA) are a worldwide clinical concern. In the present study, to explore the potential of IP as a new agent against multidrug-resistant S. aureus infections, we evaluated the antimicrobial activity of IP against multidrug-resistant S. aureus strains by MIC<sub>90</sub>, morphological observation with scanning electron microscope (SEM), and the calcein leakage assay of membrane integrity. Among the six antimicrobial peptides used in this study, IP exhibited the lowest MIC<sub>90</sub> values for both vancomycin-susceptible and -resistant S. aureus strains. The IP MIC<sub>90</sub> against a VISA strain was equivalent to vancomycin, while the MIC<sub>90</sub> against VRSA was relatively low. SEM observations indicated that bacterial cells exposed to IP were crumpled and showed prominent structural changes. Moreover, IP influenced the cell membranes of both MRSA and VRSA in a mere 5 min, leading to leakage of the preloaded calcein. Although a VISA strain was resistant to the action of IP on cell membrane, the MIC<sub>90</sub> of IP was lower than that of Nisin, suggesting that IP had another bactericidal mechanism in addition to cell membrane attack. Our results indicate that the synthetic tick antimicrobial peptide, IP exhibits strong antibacterial activity against multidrug-resistant S. aureus strains, including VRSA, via both cell membrane attack and another unknown mechanism. IP represents a promising candidate for a new anti-VRSA therapy.
Effectiveness factors for hydroprocessing of coal and coal liquids (1989)

During this quarterly report period, experimental studies were completed on the effect of solvent on ambient, non-reactive effective diffusivities for coronene in the pores of NiMo-325 catalyst. Solvents employed included cyclohexane, n-hexane, n-heptane, n-decane, and iso-octane. In addition, data were obtained for TPP in iso-octane. In addition, ambient diffusion tests with NiMo-325 for coronene in iso-octane in the presence of water were performed. Effort continued on the development of an explanation for the large value of the exponent, z (7.2 compared to the theoretical value of 4), obtained under reactive, hydroprocessing conditions, in the equation for the restrictive factor, K{sub r} = (1-{lambda})z. In addition, work was begun on the effect of solvent and temperature at reactive conditions on the restrictive factor by obtaining experimental data for the hydrogenation of Ni-TPP and Ni-TBP in decalin and mesitylene solvents with NiMo catalysts of varying particle sizes at two temperatures. 2 refs., 2 figs., 5 tabs.
A model-free approach for regulation of multi-link flexible robots (1997)

Presents a class of non-model-based position controllers for a planar multi-link flexible robot. With the controllers, one can achieve not only the closed-loop stability of the original distributed parameter system, but also the asymptotic stability of the unclamped truncated system, which is obtained through representing the deflection of each link by an arbitrary finite number of flexible modes. The system dynamics (which is very complicated in the case of a multi-link flexible robot) is not explicitly involved in the controller design and stability proof. Instead, only a very basic system energy relationship and the dynamic equations of a single-link flexible robot are utilized. The controllers possess several remarkable advantages over the traditional model-based ones. Numerical simulations are carried out on a two-link flexible robot and satisfactory results are obtained.
Reply to Comment on “Vibrational Assignments of trans-N-Methylacetamide and Some of Its Deuterated Isotopomers from Band Decomposition of IR, Visible, and Resonance Raman Spectra” (1997)

ADVERTISEMENT RETURN TO ISSUEPREVCommentReply to Comment on "Vibrational Assignments of trans-N-Methylacetamide and Some of Its Deuterated Isotopomers from Band Decomposition of IR, Visible, and Resonance Raman Spectra"Sanford A. Asher, P. Li, Zhenhuan Chi, X. G. Chen, Reinhard Schweitzer-Stenner, Noemi G. Mirkin, and Samuel KrimmView Author Information Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260 Biophysics Research Division, University of Michigan, Ann Arbor, Michigan 48109 Received: February 13, 1996; In Final Form: March 17, 1997 Cite this: J. Phys. Chem. A 1997, 101, 21, 3992–3994Publication Date (Web):May 22, 1997Publication History Published online22 May 1997Published inissue 1 May 1997https://pubs.acs.org/doi/10.1021/jp9604711https://doi.org/10.1021/jp9604711article-commentaryACS PublicationsCopyright © 1997 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views255Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (79 KB) Get e-AlertscloseSUBJECTS:Amides,Excited states,Lasers,Raman spectroscopy,Resonance structures Get e-Alerts
The role of TFPI2 hypermethylation in the detection of gastric and colorectal cancer (2017)

Gastrointestinal cancer is a prevalent disease with high morbidity and mortality. Tissue factor pathway inhibitor 2 (<i>TFPI2</i>) gene could protect the extracellular matrix of cancer cells from degradation and tumor invasion. The goal of our study was to estimate the diagnostic value of <i>TFPI2</i> hypermethylation in gastric cancer (GC) and colorectal cancer (CRC). <i>TFPI2</i> methylation was measured by quantitative methylation-specific polymerase chain reaction (qMSP) method in 114 GC and 80 CRC tissues and their paired non-tumor tissues. Our results showed that <i>TFPI2</i> methylation was significantly higher in tumor tissues (GC: 29.940% vs. 12.785%, <i>P</i> < 0.001; CRC: 26.930% vs. 5.420%, <i>P</i> < 0.001). The methylation level of <i>TFPI2</i> in colorectal tumor tissues was significantly higher than that in colorectal normal tissues (26.930% versus 0.002%, <i>P</i> < 0.00001). In GC, <i>TFPI2</i> hypermethylation yielded an area under the curve (AUC) of 0.762 (95% CI: 0.696-0.828) with a sensitivity of 68% and a specificity of 83%. In CRC, <i>TFPI2</i> hypermethylation yielded an AUC of 0.759 (95% CI: 0.685-0.834) with a sensitivity of 61% and a specificity of 84%. Similarly, TCGA data also supported <i>TFPI2</i> hypermethylation was a promising diagnostic marker for GC and CRC. Moreover, the dual-luciferase reporter assay showed <i>TFPI2</i> fragment could upregulate gene expression (fold change = 5, <i>P</i> = 0.005). Data mining further indicated that <i>TFPI2</i> expression in CRC cell lines was significantly increased after 5'-AZA-deoxycytidine treatment (fold change > 1.37). In conclusion, <i>TFPI2</i> hypermethylation might be a promising diagnostic biomarker for GC and CRC.
Prediction of Creaky Speech by Recurrent Neural Networks Using Psychoacoustic Roughness (2019)

The use of a psychoacoustic roughness model as a predictor of creaky voice is reported. We found that the roughness temporal profile of vocalic segments can predict the presence of creakiness in speech. Using a simple bi-directional Recurrent Neural Network (rnn), we were able to predict the presence of creakiness in vocalic segments from only roughness traces with an accuracy similar to that obtained with rnns trained on at least 12-dimensional input data (including amplitude difference between the first two harmonics, residual peak prominence, etc.). Training rnns with the combination of roughness and multidimensional input data improved the performance of the predictor, but not significantly. Likewise, augmenting the dataset by time derivatives of the input features did not improve the predictor's performance. The proposed roughness-based predictor eases interpretation and comparison of creakiness among corpora and suggests that roughness prediction models could be successfully used for classification of creaky intervals in speech.
Influence of Microstructure on Corrosion Resistance in Zn-Al Alloy Coating (1986)

The changes in microstructure of Zn-Al alloy coating according to the alloy composition and the cooling rate after coating were investigated, and the influence of microstructure on corrosion properties was discussed.1) When the specimens were slowly cooled at 5°C/s after coating, zinc-rich primary phase precipitated in the coatings which contained less than 5%Al. On the other hand, the coating became eutectic structure without primary phase when it contained 5.25.4%Al.2) Zn-4.5%Al alloy coatings were cooled at various rates after remelting. When the specimen was cooled at 5°C/s100°C/s, the primary phase precipitated in the coating. The microstructure of the coating became uniform when the specimen was quenched.3) The primary phase in the coating deteriorated the corrosion resistance in the salt spray test. The uniform microstructure without primary phase showed the best corrosion resistance.4) It is effective to adjust Al content precisely at eutectic composition or to cool coated sheets as rapidly as posible for getting the uniform microstructure and the good corrosion resistance.
Boosting the photovoltaic thermal stability of fullerene bulk heterojunction solar cells through charge transfer interactions (2017)

Charge transfer interaction of a donor polymer with an appropriate 9-fluorenylidene malononitrile derivative in the active layer leads to profoundly enhanced thermal stability of fullerene-based bulk heterojunction organic solar cells.
Mécanismes physiopathologiques des dysphasies développementales de l'enfant : Apport de l'IRM fonctionnelle à 3 Teslas (2011)

International audience
Aircraft Parameter Estimation Using Optimal Control Methods (2016)

In the paper at hand, a parameter estimation problem for a dynamic aircraft model is solved using direct optimal control methods. After stating the general problem, the maximum likelihood cost function is rephrased in order to formulate the problem as a standard optimal control problem. The parameters of two linear models, one for the lateral and one for the longitudinal motion of an aircraft, are estimated based on artificial measurements that have been created using a non-linear simulation. The initial guess required for the optimal control problem is created using the ordinary least squares method. The simulated results, using the identified model, show good accordance with the real output histories. The resulting dynamic properties are compared to the linearized dynamics and to results obtained with an implementation of standard parameter estimation algorithms. In both cases, close agreement was observed.
Fibrin-VLDL Receptor-Dependent Pathway Promotes Leukocyte Transmigration by Inhibiting Src Kinase Fyn and is a Target for Fibrin β15-42 Peptide (2019)

According to the current view, binding of fibrin degradation product E<sub>1</sub> fragment to endothelial VE-cadherin promotes transendothelial migration of leukocytes and thereby inflammation, and fibrin-derived β15-42 peptide reduces leukocyte transmigration by competing with E<sub>1</sub> for binding to VE-cadherin and, in addition, by signaling through Src kinase Fyn. However, the very low affinity of β15-42 to VE-cadherin raised a question about its ability to inhibit E<sub>1</sub>-VE-cadherin interaction. Further, our previous study revealed that fibrin promotes leukocyte transmigration through the very-low-density lipoprotein (VLDL) receptor (VLDLR)-dependent pathway and suggested a possible link between the inhibitory properties of β15-42 and this pathway. To test such a link and the proposed inhibitory mechanisms for β15-42, we performed in vitro experiments using surface plasmon resonance, enzyme-linked immunosorbent assay, and leukocyte transendothelial migration assay, and in vivo studies with wild-type and VLDLR-deficient mice using mouse model of peritonitis. The experiments revealed that β15-42 cannot inhibit E<sub>1</sub>-VE-cadherin interaction at the concentrations used in the previous in vivo studies leaving the proposed Fyn-dependent signaling mechanism as a viable explanation for the inhibitory effect of β15-42. While testing this mechanism, we confirmed that Fyn plays a critical role in controlling fibrin-induced transendothelial migration of leukocytes and found that signaling through the VLDLR-dependent pathway results in inhibition of Fyn, thereby increasing leukocyte transmigration. Furthermore, our in vivo experiments revealed that β15-42 inhibits this pathway, thereby preventing inhibition of Fyn and reducing leukocyte transmigration. Thus, this study clarifies the molecular mechanism underlying the VLDLR-dependent pathway of leukocyte transmigration and reveals that this pathway is a target for β15-42.
Simulator motion-drive algorithms - A designer's perspective (1990)

Changes in the design of software algorithms for generating physical motion in flight simulators have typically been put forward on the grounds of improved motion cueing. Little attention has been paid to more practical criteria such as computational cost, ease of adjustment, or evaluation by experienced pilots in a realistic simulation environment. A comparison of three of the algorithms most commonly found in the literature has been performed: classical washout, optimal control, and coordinated adaptive. This consisted of pilot evaluations of these algorithms implemented on a six-degree-of-freedom flight simulator simulating a large transport aircraft during low-altitude flight and ground maneuvering. This paper presents the results of that study from the designer's viewpoint. In it, we contend that, with enough effort, most algorithms can be massaged to perform reasonably well, and that a more important consideration is the ease with which a given algorithm can be brought to high performance levels. If this criterion is used, it appears that the classical algorithm is a good starting point, and that the benefits of an adaptive algorithm can be added gradually to obtain the advantages conferred by nonlinear filtering and intelligent cost functions.
Identification of a complementary-DNA clone containing part of the sequence information for the C1-polypeptide of rat prostatic binding protein (1982)

Conference Article| February 01 1982 Identification of a complementary-DNA clone containing part of the sequence information for the C1-polypeptide of rat prostatic binding protein BERNARD DELAEY; BERNARD DELAEY *Afdeling Biochemie, Departement Humane Biologie, Rega Instituut, B-3000 Leuven, Belgium Search for other works by this author on: This Site PubMed Google Scholar WILFRIED ROMBAUTS; WILFRIED ROMBAUTS *Afdeling Biochemie, Departement Humane Biologie, Rega Instituut, B-3000 Leuven, Belgium Search for other works by this author on: This Site PubMed Google Scholar GUIDO VOLCKAERT; GUIDO VOLCKAERT *Afdeling Biochemie, Departement Humane Biologie, Rega Instituut, B-3000 Leuven, Belgium Search for other works by this author on: This Site PubMed Google Scholar BEN PEETERS; BEN PEETERS †Laboratorium voor Experimentele Geneeskunde, Katholieke Universiteit Leuven, B-3000 Leuven, Belgium Search for other works by this author on: This Site PubMed Google Scholar JAN MOUS; JAN MOUS †Laboratorium voor Experimentele Geneeskunde, Katholieke Universiteit Leuven, B-3000 Leuven, Belgium Search for other works by this author on: This Site PubMed Google Scholar WALTER HEYNS WALTER HEYNS †Laboratorium voor Experimentele Geneeskunde, Katholieke Universiteit Leuven, B-3000 Leuven, Belgium Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1982) 10 (1): 51. https://doi.org/10.1042/bst0100051 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Cite Icon Cite Get Permissions Citation BERNARD DELAEY, WILFRIED ROMBAUTS, GUIDO VOLCKAERT, BEN PEETERS, JAN MOUS, WALTER HEYNS; Identification of a complementary-DNA clone containing part of the sequence information for the C1-polypeptide of rat prostatic binding protein. Biochem Soc Trans 1 February 1982; 10 (1): 51. doi: https://doi.org/10.1042/bst0100051 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu nav search search input Search input auto suggest search filter All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1982 Biochemical Society1982 Article PDF first page preview Close Modal You do not currently have access to this content.
Dosable solvates of ivacaftor with high boiling point liquids (2012)

Ivacaftor (also known as VX-770) is a small molecule currently in development for treatment of cystic fibrosis. In the present work, we describe an effort to create novel solvates, formed with 2-methylbutyric acid and isobutyric acid respectively, in pursuit of a more robust and reliable scale-up process. The solvates were characterized by X-ray crystallography, X-ray diffraction, differential scanning calorimetry, thermogravimetric analysis, and dynamic vapor sorption. The vapor sorption analysis showed the isobutyric acid solvate to be less stable than the 2-methylbutyric acid solvate, which became the focus of subsequent investigations. The 2-methylbutyric acid solvate was administered to rats and dogs in a series of pharmacokinetic studies, and showed excellent in vivo bioavailability. Thus, using liquid-state co-formers led to a solid form that is bioavailable, as well as stable and processable, suggesting that using such liquid-state co-formers could potentially benefit pharmaceutical development more broadly.
Lumbar pedicle cortical bone trajectory screw (2014)

CBT technique is a better alternative option of lumbar pedicle fixation, especially for patients with osteoporosis and obesity.
ChemInform Abstract: ACTIVATION OF METHANE WITH METAL ATOMS AT 10 K WITHOUT PHOTOLYSIS (1983)

Abstract Untersuchungen zeigen, daß Al‐Atome mit Methan bei 0 Kreagieren ‐ es entstehen Methyl‐Al‐hydride, während Mg, Ca, Ti, Cr, Fe, Co, Ni, Pd, Cu, Ag, Au, Ga, In und Sn unter analogen Bedingungen keine Reaktionen eingehen.