gebhart/patrepeval huggingface dataset:
Functional Monolithic Polymeric Organic Framework Aerogel as Reducing and Hosting Media for Ag nanoparticles and Application in Capturing of Iodine Vapors (2012)

Monolithic aerogels of polymeric organic framework (Mon-POF) with a high density of OH functional groups were synthesized through solvothermal polymerization of terephthalaldehyde and 1,5-dihydroxynaphthalene. This POF material presents high surface area of 1230 m2 g–1 having micro-, meso-, macropores, and low bulk density of 0.15 g cm–3. The evolution of the porous properties is controlled with the polymerization rate. Mon-POF is stable under acidic and basic conditions. The presence of high number of OH functional groups provides the monolith with ion-exchange properties as well as reducing properties. The Mon-POF adsorbs Ag+ from aqueous solution to deposit Ag nanoparticles into the pores at a high loading content ∼25 wt % of the composite material. The Ag loaded monolith captures significant amount of I2 vapor and fixes it effectively in the form of β-AgI.
From harvesting to cultivating (2009)

Much has been written about the lifecycle of digital objects. This study is instead concerned with the lifecycle of collections and associated services. Online collection environments are built to fulfill specific collecting objectives and constraints. If a collection proves useful within its original hosting environment, it will often be necessary or desirable to move the collection to new environments, in order to support new forms of use and re-aggregation or extract resources from legacy data environments. Such a transformation can be extremely expensive, challenging and prone to error, especially if the collections include complex internal structures and services. When "services make the repository" [1], moving raw data from one location to another will often not be sufficient. Digital curators can pre-empt costly and problematic system migration efforts by integrating collections into environments specifically designed to support long-term preservation, scalability and interoperability [2]. We report on an integration of content and functionality of a feature-rich collecting environment (ContextMiner) into a robust data curation environment (iRODS).
Active force control for Robotic Micro-Assembly : Application to guiding tasks. (2010)

International audience
Analysis of Optimal Combining in Rician Fading with Co-channel Interference (2017)

Approximate Symbol error rate (SER), outage probability and rate expressions are derived for receive diversity system employing optimum combining when both the desired and the interfering signals are subjected to Rician fading, for the cases of a) equal power uncorrelated interferers b) unequal power interferers c) interferer correlation. The derived expressions are applicable for an arbitrary number of receive antennas and interferers and for any quadrature amplitude modulation (QAM) constellation. Furthermore, we derive a simple closed form expression for SER in the interference-limited regime, for the special case of Rayleigh faded interferers. A close match is observed between the SER, outage probability and rate results obtained through the derived analytical expressions and the ones obtained from Monte-Carlo simulations.
Electrochemical Quantification of Glycated and Non-glycated Human Serum Albumin in Synthetic Urine (2019)

A polymer-based electrode capable of specific detection of human serum albumin, and its glycated derivatives, is described. The sensor is constructed from a glass microscope slide coated with a synthesized, polythiophene film bearing a protected, iminodiacetic acid motif. The electrode surface is then further elaborated to a functional biosensor through deprotection of the iminodiacetic acid, followed by metal-affinity immobilization of a specific and high-affinity, albumin ligand. Albumin was then quantified in buffer and synthetic urine via electrochemical impedance spectroscopy. Glycated albumin was next bound to a boronic acid-modified, single-cysteine dihydrofolate reductase variant to quantify glycation ratios by square-wave voltammetry. The platform offers high sensitivity, specificity, and reproducibility in an inexpensive arrangement. The detection limits exceed the requirements for intermediate-term glycemic control monitoring in diabetes patients at 5 and 1 nM for albumin and its glycated forms, respectively.
Emission and focusing characteristics of volcano-structured double-gated field emitter arrays (2009)

Volcano-structured double-gated field emitter arrays (VDG-FEAs) with different focusing electrode height have been fabricated and the focusing characteristics for each VDG-FEAs were evaluated in detail. The authors experimentally proved that lowering the focusing electrode was very effective to keep a high emission current and successfully removed the electric field relaxation at the tip during the focusing operation. The anode current of about 1.9μA was maintained for the VDG-FEA with the height of the focusing electrode relative to the extraction electrode, hf=−470nm, even in applying 5V to the focusing electrode, and the current was 84.4 times larger, compared with the sample with hf=220nm under the same focusing condition. It was found that the emitted electrons returned back to the extraction electrode by the potential barrier caused by the low focusing potential below 3V in every sample.
Aberration Correction Of Speckled Imagery With An Image-Sharpness Criterion (1988)

Researchers have shown that aberrations in incoherent optical systems can be corrected through the use of an image-sharpness criterion [1]. An analogous image-sharpness criterion is defined for the case of speckled imagery derived from coherent imaging of diffuse objects. By appealing to a multiplicative noise model we show that this speckled-image sharpness criterion is a random variable with an expected value proportional to the sharpness criterion for the associated incoherent image. Thus, aberration correction can be accomplished by maximizing the speckled-image sharpness criterion. A variety of computer simulation experiments designed to test the performance of the image-sharpness criterion applied to speckled imagery are presented. These experiments model the problem of imaging moving targets with synthetic aperture radar (SAR). Target motion introduces one-dimensional (azimuthal) phase aberrations in SAR Fourier data producing a one-dimensional blur in the image. These aberrations can be represented as a linear sum of orthogonal polynomials and the coefficients of such a representation serve as optimization parameters. The sharpness criterion is maximized with respect to the aberration parameters through the use of a conjugate-gradient algorithm. The problem of entrapment by local minima can be overcome by using multiple initial estimates. We demonstrate that quadratic, cubic, and quartic polynomial coefficients are successfully sensed through this technique. The method is shown to succeed for both extended images and point-like images that more closely resemble SAR images of cultural targets.
Effiziente Pulsverkürzung mittels phasenkonjugierenden Brillouin Spiegeln (2006)

Im Mittelpunkt der Arbeit steht die effiziente Pulskompresion durch Anregung der SBS. Kurze Pulse im sub-Nanosekundenbereich wurde mit hoher Effizienz generiert.
Graphene Oxide membranes for phase-selective microfluidic flow control (2015)

This paper investigates the unique properties of multilayer Graphene Oxide (GO) as a barrier selective to solvents, as well as the state of aggregation of fluids. To this end, we developed novel processes for the assembly of GO as membranes into polymeric microfluidic systems. We demonstrate that GO blocks pressurized air and organic solutions while it is permeable to water. It is planned to employ these GO membranes as a flow control element in a microfluidic system.
Effect of Micro- and Nanoscale Topography on the Adhesion of Bacterial Cells to Solid Surfaces (2013)

Attachment and biofilm formation by bacterial pathogens on surfaces in natural, industrial, and hospital settings lead to infections and illnesses and even death. Minimizing bacterial attachment to surfaces using controlled topography could reduce the spreading of pathogens and, thus, the incidence of illnesses and subsequent human and financial losses. In this context, the attachment of key microorganisms, including Escherichia coli, Listeria innocua, and Pseudomonas fluorescens, to silica and alumina surfaces with micron and nanoscale topography was investigated. The results suggest that orientation of the attached cells occurs preferentially such as to maximize their contact area with the surface. Moreover, the bacterial cells exhibited different morphologies, including different number and size of cellular appendages, depending on the topographical details of the surface to which they attached. This suggests that bacteria may utilize different mechanisms of attachment in response to surface topography. These results are important for the design of novel microbe-repellant materials.
Pressure Profile in Annulus: Solids Play a Significant Role (2015)

This paper looks into the effects of solids on the wellbore pressure profile under different conditions. An extensive number of experiments were conducted on a 90-ft-long, 4.5 in. × 8 in. full-scale flow loop to simulate field conditions. The flow configurations are analyzed. A solid–liquid two-phase flow configuration map is proposed. Significant difference is found between the pressure profile with solids and without solids in the wellbore. The results of this study show how the pressure profile in the wellbore varies when solids present in the annulus, which may have important applications in drilling operations.
Transmission of 400-Gbps Discrete Multi-Tone Signal Using >100-GHz-Bandwidth Analog Multiplexer and InP Mach-Zehnder Modulator (2018)

The following topics are dealt with: optical modulation; optical fibre communication; optical fibre networks; wavelength division multiplexing; integrated optics; quadrature amplitude modulation; silicon; optical communication equipment; optical fibre amplifiers; optical switches.
The Correction of Stress Incontinence by Simple Vesicourethral Suspension (2002)

SummaryThe development of a new operation for certain types of urinary incontinence has been described. A preoperative test, consisting essentially of temporary elevation and fLxation of the vesical neck and urethra, has permitted the selection of those candidates who have an excellent chance for improvement by the operation, and which at the same time seems to indicate those whose postoperative result will not be good. The operation is a simple elevation and immobilization of the vesical neck and urethra by suturing them to the pubis and rectus muscles. Of 44 suitable cases excellent results were obtained in 36 (82%), significant improvement in 3 (7%), and no improvement in 5 (11%). The causes of most of the failures seem evident and are discussed. The most significant group reported consisted of 25 patients with the common variety of female stress incontinence which had failed to be corrected by one or more standard gynecological procedures for incontinence. Of these 25 patients, 19 have normal control ...
Some features of the SIMULA 67 language (1968)

SIMULA 67 is a general purpose programming language with a built-in simulation capability similar to, but stronger than that of SIMULA I. SIMULA 67 has been developed by the authors at the Norwegian Computing Center. Compilers for this language are now being implemented on a number of different computers. Other compilers are in the planning stage.A main characteristic of SIMULA 67 is that it is easily structured towards specialized problem areas, and hence will be used as a basis for special application languages.SIMULA 67 contains the general algorithmic language ALGOL 60 as a subset, except for some very minor revisions. The reason for choosing ALGOL 60 as starting point was that its basic structure lent itself for extension. It was felt that it would be impractical for the users to base SIMULA 67 on still another new algorithmic language, and ALGOL 60 has already a user basis, mainly in Europe and the Soviet.
Integrating Computational Methods in Network Pharmacology andIn SilicoScreening to Uncover Multi-targeting Phytochemicals against Aberrant Protein Glycosylation in Lung Cancer (2023)

Glycoproteins are an underexploited drug target for cancer therapeutics. In this work, we integrated computational methods in network pharmacology and <i>in silico</i> docking approaches to identify phytochemical compounds that could potentially interact with several cancer-associated glycoproteins. We first created a database of phytochemicals from selected plant species, <i>Manilkara zapota</i> (sapodilla/chico), <i>Mangifera indica</i> (mango), <i>Annona muricata</i> (soursop/guyabano), <i>Artocarpus heterophyllus</i> (jackfruit/langka), <i>Lansium domesticum</i> (langsat/lanzones), and <i>Antidesma bunius</i> (bignay), and performed pharmacokinetic analysis to determine their drug-likeness properties. We then constructed a phytochemical-glycoprotein interaction network and characterized the degree of interactions between the phytochemical compounds and with cancer-associated glycoproteins and other glycosylation-related proteins. We found a high degree of interactions from α-pinene (<i>Mangifera indica</i>), cyanomaclurin (<i>Artocarpus heterophyllus</i>), genistein (<i>Annona muricata</i>), kaempferol (<i>Annona muricata</i> and <i>Antidesma bunius</i>), norartocarpetin (<i>Artocarpus heterophyllus</i>), quercetin (<i>Annona muricata</i>, <i>Antidesma bunius</i>, <i>Manilkara zapota</i>, <i>Mangifera indica</i>), rutin (<i>Annona muricata</i>, <i>Antidesma bunius</i>, <i>Lansium domesticum</i>), and ellagic acid (<i>Antidesma bunius</i> and <i>Mangifera indica</i>). Subsequent docking analysis confirmed that these compounds could potentially bind to EGFR, AKT1, KDR, MMP2, MMP9, ERBB2, IGF1R, MTOR, and HRAS proteins, which are known cancer biomarkers. <i>In vitro</i> cytotoxicity assays of the plant extracts showed that the <i>n</i>-hexane, ethyl acetate, and methanol leaf extracts from <i>A. muricata</i>, <i>L. domesticum</i> and <i>M. indica</i> gave the highest growth inhibitory activity against A549 lung cancer cells. These may help further explain the reported cytotoxic activities of select compounds from these plant species.
Terbinafine-induced lichenoid drug eruption (2016)

Drug-induced lichen planus has been induced by antibiotics, anticonvulsants, antidiabetics, antimalarials, antitubercular drugs, antihypertensives, psychiatric drugs, chemotherapeutic agents, diuretic, heavy metals, NSAIDs, etc. Terbinafine, an antifungal agent, is widely used for dermatophyte infections and onychomycosis. Cutaneous adverse effects of terbinafine are rarely reported. Here, we report a case of terbinafine-induced lichenoid drug eruption in a 22-year-old who presented with generalized lichenoid eruption 2 weeks after terbinafine initiation of. The body and lip cleared completely after 8 weeks of drug withdrawal; nail change cleared after 12 weeks.
Fabrication of Molds with 25-nm Dot-Pitch Pattern by Focused Ion Beam and Reactive Ion Etching for Nanoimprint Using Metallic Glass (2012)

Here we attempted to fabricate molds (dies) of nanodot arrays with a 25-nm pitch and to nanoimprint metallic glass for developing bit-patterned media with an ultrahigh recording density of 1 Tbit/in. 2 . The mold-fabricating process consisted of mask patterning by focused ion beam assisted chemical vapor deposition (FIB-CVD) and reactive ion etching (RIE). We investigated the feasibility of a Pt-deposited metal etching mask on SiO 2 on Si and diamond like carbon (DLC) on Al 2 O 3 substrates, and achieved isolated convex nanodot arrays with a 25-nm pitch and an aspect ratio of 1.8 by RIE with O 2 plasma on a DLC/Al 2 O 3 substrate. Subsequently, we nanoimprinted Pt-based metallic glass by using the fabricated molds and successfully replicated fine concave nanohole arrays. The results suggest that the FIB-CVD/RIE process is a promising technique for fabricating ultrafine nanopatterned molds, and metallic glasses are ideal nanoimprintable materials for mass producing nanodevices such as bit-patterned media.
Drum centrifuge tests of surface and embedded footings on sand (2006)

Circular footing tests on sand have been carried out in the UWA drum centrifuge at a radial acceleration of 100 g. The main purpose of the experiments was to compare the combined loading response of a surface circular plate, a buried plate and a skirted foundation. The embedment depth to diameter ratio (L/D) of both the embedded foundation models was 0.5. Vertical loading, radial displacement and swipe tests producing vertical (V) and horizontal loads and overturning moment (M) loads have been carried out for each foundation type. Combined loads were applied by using a fixed arm to apply predominantly horizontal loading and a hinged arm to achieve a direct rotation of the foundation about its load reference point. All the experiments have been designed and conducted to allow the results to be interpreted within a strain hardening plasticity framework. © 2006 Taylor & Francis Group, London.
Photoreceptor Mitochondrial Oxidative Stress in Experimental Autoimmune Uveitis (2008)

In experimental autoimmune uveitis (EAU), the macrophages infiltrate the retina during the late phase, 10-14 days after immunization with uveitogenic antigen, causing photoreceptor damage. However, prior to inflammatory cell infiltration, during the early phase (5-7 days after immunization), increased generation of reactive oxygen and nitric oxide species was observed in the photoreceptor mitochondria indicating oxidative stress. The oxidative-stress-induced nitration of photoreceptor mitochondrial proteins and peroxidation of membrane lipids led to activation and migration of microglia toward the photoreceptors. These observations suggest oxidative stress could be an initial pathologic event leading to amplification of inflammation inducing photoreceptor damage, thereby causing clinical and histologic expression of uveitis in the form of inflammatory cell infiltration.
Plume detection with emphasis on phenomenology, signal models, and exploitation algorithms (2017)

The remote detection, identification and quantification of chemical vapor plumes in the atmosphere are difficult problems that have been addressed using longwave hyperspectral sensors. Chemical detection algorithms compare the sensor's spectral measurements to a library of known chemical signatures to decide whether or not a plume is present. Detection of the chemical plume is an important step in the processing pipeline, but the main goal of the system is to accurately identify which single chemical or mixture of chemicals is present in the plume. In this paper, we provide the key equations and methods used for chemical detection and identification, system performance evaluation, as well as a comparison of state-of-the-art processing algorithms. We show that a good practical approach is a two-step algorithm design that uses a bank of single-chemical detectors, followed by an identification algorithm that makes a final decision about the chemicals in the plume.
False Molecular Clusters due to Nonrandom Association of IS 6110 with Mycobacterium tuberculosis (2000)

ABSTRACT We sought to determine whether nonrandom association of IS 6110 with Mycobacterium tuberculosis could result in false-positive clustering in unselected collections of isolates. We typed 196 strains of M. tuberculosis from an unselected community-based study in northern Tanzania by IS 6110 and polymorphic GC-rich repetitive-sequence (PGRS) methodologies. The strains were analyzed by Gelcompar computer software. Analysis of 13 out of 25 groups showed that isolates with identical IS 6110 and PGRS patterns were likely to be the same strain. Some IS 6110 groups containing strains with identical PGRS patterns had similar IS 6110 patterns that differed only by movement of the element. Isolates assigned to a single group (i.e., group 11) on the basis of sharing an identical IS 6110 fingerprint pattern did not share identical PGRS fingerprint patterns. Six out of the nine bands in these isolates were in hot-spot locations, as previously defined. This indicates that nonrandom association may result in false-positive clustering in unselected community-based studies. Only strains with identical PGRS and IS 6110 patterns are likely to be recently transmitted.
Probing the time-dependent switching probability of individual patterned magnetic islands (2011)

We show switching probability measurements of individual bits of a bit patterned media in the highly inhomogeneous write field of a recording head. The behavior of the switching probability as a function of the applied field pulse width t deviates from a simple Arrhenius—Néel model for the magnetization reversal. The data agree well with an extended model that assumes a normal distribution of energy barriers. We compare the extracted energy barrier distribution to the switching field distribution in a uniform perpendicular magnetic field measured at long time scales.
Hippocampal Membrane-Associated p75NTR Levels are Increased in Alzheimer's Disease (2012)

The pan-specific p75 neurotrophin receptor (p75(NTR)) is believed to play an important role in the pathogenesis of Alzheimer's disease (AD). It is involved in mediating amyloid-β (Aβ) toxicity and stimulating amyloidogenesis. In addition, we have recently shown that stimulating cultured SH-SY5Y human neuroblastoma cells with Aβ(42) increases the level of membrane-associated p75(NTR) and that Aβ(42)-accumation in two strains of transgenic AD model mice is accompanied by an increased level of hippocampal membrane-associated p75(NTR) (Chakravarthy et al. J Alzheimers Dis 19, 915-925, 2010). This raised an important question whether accumulating Aβ(42) in human AD is also accompanied by an increased hippocampal membrane-associated p75(NTR). In this study, using polyclonal and monoclonal antibodies against the p75(NTR) receptor's intra- and extracellular domains, we show that indeed the mean level of membrane-associated p75(NTR) in the hippocampal formation is significantly higher (~two-fold, p < 0.03) in human AD brains than in identical samples of hippocampal formation in age-matched non-AD human brains. The possible relation of this elevated hippocampal p75(NTR) to AD cognitive decline is discussed.
Efficient metamaterial flat lenses (2014)

We recently demonstrated ultrathin, broadband, and highly efficient (reaching 88%) terahertz (THz) metamaterial structures exhibiting near-perfect anomalous (or generalized laws of) refraction. These structures redirect up to 61% of the incident power into the anomalous beam and practically eliminate the ordinary component. Here exploit this breakthrough to create more complex optical elements, specifically a highly efficient metamaterial flat lens.