gebhart/patrepeval huggingface dataset:
Implementation of searchable symmetric encryption for privacy-preserving keyword search on cloud storage (2015)

Abstract Ensuring the cloud data security is a major concern for corporate cloud subscribers and in some cases for the private cloud users. Confidentiality of the stored data can be managed by encrypting the data at the client side before outsourcing it to the remote cloud storage server. However, once the data is encrypted, it will limit server’s capability for keyword search since the data is encrypted and server simply cannot make a plaintext keyword search on encrypted data. But again we need the keyword search functionality for efficient retrieval of data. To maintain user’s data confidentiality, the keyword search functionality should be able to perform over encrypted cloud data and additionally it should not leak any information about the searched keyword or the retrieved document. This is known as privacy preserving keyword search. This paper aims to study privacy preserving keyword search over encrypted cloud data. Also, we present our implementation of a privacy preserving data storage and retrieval system in cloud computing. For our implementation, we have chosen one of the symmetric key primitives due to its efficiency in mobile environments. The implemented scheme enables a user to store data securely in the cloud by encrypting it before outsourcing and also provides user capability to search over the encrypted data without revealing any information about the data or the query.
Structures of Dysprosium(III) Triflates in Water, Methanol, and 2-Propanol As Studied by 17O and 19F NMR Spectroscopy (1999)

The structures of Dy(CF3SO3)3 in water, methanol, and 2-propanol have been investigated with the use of multinuclear NMR techniques. Dy(III)-induced 17O NMR shifts of the solvent afforded estimates of the average number of inner-sphere solvent molecules. Information on the location of the triflate anion was obtained by longitudinal 19F relaxation rates. The data suggest that the predominant species in the various solvents are [Dy(H2O)8][CF3SO3]3, [Dy(CF3SO3)1-2(CH3OH)6][CF3SO3], and Dy(CF3SO3)3(i-PrOH)3. Upon addition of water to solutions of Dy(CF3SO3)3 in anhydrous organic solutions the solvent molecules and the triflate anions are expelled from the first coordination sphere of Dy(III) simultaneously.
Bilinear modelling of batch processes. Part I: theoretical discussion (2008)

Abstract When studying the principal component analysis (PCA) or partial least squares (PLS) modelling of batch process data, one realizes that there is a wide range of approaches. In many cases, new modelling approaches are presented just because they work properly for a particular application, for example, on‐line monitoring and a given number of processes. A clear understanding of why these approaches perform successfully and which are the advantages and disadvantages in front of the others is seldom supplied. Why does modelling after batch‐wise unfolding capture changing dynamics? What are the consequences of variable‐wise unfolding? Is there any best unfolding method? When should several models for a single process be used? In this paper, it is shown how these and other related questions can be answered by properly analyzing the dynamic covariance structures of the various approaches. Copyright © 2008 John Wiley &amp; Sons, Ltd.
Earnings Forecasts and the Predictability of Stock Returns: Evidence from Trading the S&amp;amp;P (1997)

We develop a simple error-correction model, based on a well-known theory, espoused by Benjamin Graham and David Dodd and others, which presumes stock returns tend to restore an equilibrium relationship between the forecasted earnings yield on common stocks and the yield on bonds. The estimation uses I/B/E/S analysts forecasts of S&amp;amp;amp;amp;amp;P; earnings. To evaluate the model, we use rolling regressions to obtain out-of-sample forecasts of excess returns. Tests of association show the implicit timing signals to be statistically significant. Further, a strategy of investing in cash, when the excess return forecast is negative, and investing in the S&amp;amp;amp;amp;amp;P;, when the excess return forecast is positive, outperforms the S&amp;amp;amp;amp;amp;P; with higher returns and smaller volatility. Using the bootstrap methodology, we demonstrate that the findings are statistically significant.
Unusual Behavior in the First Excited State Lifetime of Catechol (2013)

We are presenting vibrationally selective pump–probe measurements of the first electronic excited-state (ππ*) lifetime of jet-cooled neutral catechol (1,2-dihydroxybenzene). The lifetime of the 0–0 transition is very short (7 ps) as rationalized by the small ππ*/πσ* gap calculated. However, the lifetimes implying higher out-of-plane vibrational levels are longer (∼11 ps). This emphasizes the role of the out-of-plane vibration in the ππ*/πσ* coupling, not only in its nature, but also in the number of quanta.
Two different protein-protein interactions in oligomeric complexes of SV40 large T antigen with the cellular oncoprotein p53. (1989)

The simian virus 40 (SV40) large T antigen appears in monomers, dimers and various high molecular weight homo-oligomers. EDTA treatment of cell extracts from SV40-infected and -transformed cells leads to a dissociation of the high molecular weight oligomers which can be reconstituted by dialysis against an EDTA free buffer. Hetero-oligomers, composed of T antigen and the oncoprotein p53 become disassembled in the presence of EDTA into forms sedimenting minimally at 7S and maximally at 14S. These low molecular weight T-p53 complexes are resistant to EDTA treatment. Therefore, our results suggest at least two kinds of protein-protein interactions, an EDTA resistant linkage between large T antigen and p53 and an EDTA-sensitive ionic interaction between T antigen molecules in highly oligomeric complexes.
Three behavioral states observed in field emission from single-walled carbon nanotubes (1999)

We observe three distinct behavioral states in field emission from single-walled carbon nanotubes between temperatures of 300 and 1800 K. At room temperature, nanotubes emit through adsorbate states correlated to the presence of water. These states are removed above 900 K. After adsorbate removal, the apparently clean nanotube state shows lower emission current and substantially reduced emission noise. Current-temperature measurements identify a deviation from metallic tunneling behavior. Nanotube field emission undergoes a second, field-stabilized transition at high temperatures which reduces the current by as much as five orders of magnitude relative to the room temperature current. This current decrease is 100% recoverable. In addition, the stable behavior of clean nanotube states breakdown at extremely high currents and temperatures. Rings form around the field emission images, similar to those observed in metals at extreme current densities. Under these extreme conditions, we also find evidence for the rearrangement of atoms on the nanotube caps.
Correction: Reusable manganese compounds containing pyrazole-based ligands for olefin epoxidation reactions (2015)

Correction for 'Reusable manganese compounds containing pyrazole-based ligands for olefin epoxidation reactions' by Ester Manrique et al., Dalton Trans., 2015, 44, 17529-17543.
The adaptation of noise-induced temporary hearing threshold shift predictive models for modelling the public health policy (2023)

The final TTS predictive model proposed in this study needs to be validated in larger groups of subjects exposed to noise. Actual prediction of TTS episodes in general populations may become a helpful tool in creating the hearing protection public health policy. Int J Occup Med Environ Health. 2023;36(1):125-38.
Supplementary Fig. S3 from EphA4 promotes cell proliferation and migration through a novel EphA4-FGFR1 signaling pathway in the human glioma U251 cell line (2023)

Supplementary Fig. S3 from EphA4 promotes cell proliferation and migration through a novel EphA4-FGFR1 signaling pathway in the human glioma U251 cell line
C2P: Clustering based on Closest Pairs (2001)

In this paper we present C 2 P, a new clustering algorithm for large spatial databases, which exploits spatial access methods for the determination of closest pairs. Several extensions are presented for scalable clustering in large databases that contain clusters of various shapes and outliers. Due to its characteristics, the proposed algorithm attains the advantages of hierarchical clustering and graphtheoretic algorithms providing both efficiency and quality of clustering result. The superiority of C 2 P is verified both with analytical and experimental results. 1
Effect of polylysine on the leakage and retention of compounds by Ehrlich ascites tumor cells. (1961)

Summary Washed Ehrlich ascites tumor cells were suspended in either a saline or a polylysine saline solution. The cells were centrifuged, and the supernatant above the polylysine-treated or control cells or the cell pellet was studied. Inorganic phosphate, carbohydrate, free amino acids, small peptides, potassium, and adenosine-5′-monophosphate were released from the tumor cells into the supernatant after polylysine treatment. Polylysine blocked the release of proteins and phospholipides, which passed into the suspending medium from the control cells. Antisera against Ehrlich ascites cells caused a similar change in morphology and leakage and retention of compounds from the tumor cells. This suggests that antibody-complement and polylysine may affect similar sites.
Poly(ethylene glycol): Protein-repulsive or albumin-compatible? (2000)

In the literature, many papers deal with the behavior of proteins in aqueous media in the presence of poly(ethylene glycol) (PEG) molecules or poly(ethylene oxide) (PEO) segments, physically adsorbed onto, or covalently attached to, macromolecules or to solid surfaces. In particular, it is well known that PEO segments make foreign materials stealthy, i.e. they are much less detected by the immune system either through humoral reactions or, at the cell level, through opsonins. Revisiting the literature led us to challenge the largely accepted opinion that the decreased recognition of PEO segment-bearing foreign macromolecules and particles by the mononuclear phagocyte system is primarily the consequence of the repulsion of all blood proteins by PEG segments through the excluded volume effect. This challenge is based on the finding that albumin and PEG are compatible in phosphate-buffered saline at room temperature and at concentrations comparable to those measured by others on the surface of PEO segment-bearing species, whereas fibrinogen and PEG phase-separated and were incompatible despite the much lower concentration of the latter protein. According to literature and to these observations, it is proposed that the stealth effect induced by PEO segments is primarily due to the compatibility between PEO segments of intermediate molar mass and albumin, thus rendering PEO-bearing macromolecules or surfaces to look like native albumin. Under such conditions, the hospitality offered by PEG macromolecules or PEO segments to albumin, the dominant plasma protein, results in a 'chameleon' effect that prevents the activation of other PEG-compatible or -incompatible plasma proteins or cells involved in foreign body recognition and elimination. PEG with molar masses > or = 8000 did not accommodate albumin in agreement with the excluded volume phenomenon.
Crystal Structure of an Engineered LRRTM2 Synaptic Adhesion Molecule and a Model for Neurexin Binding (2016)

Synaptic adhesion molecules are key components in development of the brain, and in the formation of neuronal circuits, as they are central in the assembly and maturation of chemical synapses. Several families of neuronal adhesion molecules have been identified such as the neuronal cell adhesion molecules, neurexins and neuroligins, and in particular recently several leucine-rich repeat proteins, e.g., Netrin G-ligands, SLITRKs, and LRRTMs. The LRRTMs form a family of four proteins. They have been implicated in excitatory glutamatergic synapse function and were specifically characterized as ligands for neurexins in excitatory synapse formation and maintenance. In addition, LRRTM3 and LRRTM4 have been found to be ligands for heparan sulfate proteoglycans, including glypican. We report here the crystal structure of a thermostabilized mouse LRRTM2, with a Tm 30 °C higher than that of the wild-type protein. We localized the neurexin binding site to the concave surface based on protein engineering, sequence conservation, and prior information about the interaction of the ligand with neurexins, which allowed us to propose a tentative model for the LRRTM-neurexin interaction complex. We also determined affinities of the thermostabilized LRRTM2 and wild-type LRRTM1 and LRRTM2 for neurexin-β1 with and without Ca(2+). Cell culture studies and binding experiments show that the engineered protein is functional and capable of forming synapselike contacts. The structural and functional data presented here provide the first structure of an LRRTM protein and allow us to propose a model for the molecular mechanism of LRRTM function in the synaptic adhesion.
Localization of chronic myocardial infarction using body surface Laplacian maps (2002)

Body surface Laplacian mapping was performed on two male inpatients with prior myocardial infarction (MI) as determined by cardiac echocardiography and ECG changes. From 150 channels of potential ECGs, the Laplacian ECGs were estimated and the body surface Laplacian maps (BSLMs) were constructed using a 32 level color scale. In both patients with anterior MW, the BSLMs showed a localized initial negativity appearing at mid Q-R and overlying the site of MI as determined by ECG and echocardiographic criteria. The localization of MI was consistent with previous studies specifying the site of infarct as the peak negativity during early QRS in potential maps. This study, suggests that the BSLM provides better localization of the anterior MI as compared to potential maps and may provide potential benefit in assisting clinical diagnosis.
Subunit interactions in aspartate transcarbamylase. Characterization of a complex between the catalytic and the regulatory subunits (1975)

The complex formed when excess regulatory subunits (r2) of aspartate transcarbamylase is added to a dilute solution of the catalytic subunit (c3) has been further studied. By stabilizing the complex with saturating levels or r2, it was possible to perform ultracentrifugation in sucrose density gradients. The sedimentation coefficient of the complex (7.7 plus or minus 0.2 S) is intermediate between those of the catalytic subunit (5.8 S) and of the native enzyme (11.7 S). Consideration of the likely hydrodynamic properties of the complex suggests that this sedimentation coefficient may be consistent with the c3r6 structure previously proposed. The formation of c3r6 from c3 and r2 is readily reversible. At nonsaturating levels or r2, conversion to the native enzyme (c3r6) takes place. This conversion is inhibited by high concentrations of r2. The c3r6 complex shows Michaelis-Menten kinetics with a low Km for aspartate and considerable substrate inhibition. The pH activity profile at high aspartate concentrations is almost identical with that of the native enzyme. All of these observations suggest that c3r6 represents the relaxed (R) state of aspartate transcarbamylase. The insensitivity of c3r6 toward CTP or ATP can also be explained by considering c3r6 as a stabilized relaxed state. These properties of c3r6 have significant implications regarding the allosteric mechanism of the native enzyme.
The role of pheromone receptors for communication and mating in Hypocrea jecorina (Trichoderma reesei) (2012)

Discovery of sexual development in the ascomycete Trichoderma reesei (Hypocrea jecorina) as well as detection of a novel class of peptide pheromone precursors in this fungus indicates promising insights into its physiology and lifestyle. Here we investigated the role of the two pheromone receptors HPR1 and HPR2 in the H. jecorina pheromone-system. We found that these pheromone receptors show an unexpectedly high genetic variability among H. jecorina strains. HPR1 and HPR2 confer female fertility in their cognate mating types (MAT1-1 or MAT1-2, respectively) and mediate induction of fruiting body development. One compatible pheromone precursor-pheromone receptor pair (hpr1-hpp1 or hpr2-ppg1) in mating partners was sufficient for sexual development. Additionally, pheromone receptors were essential for ascospore development, hence indicating their involvement in post-fertilisation events. Neither pheromone precursor genes nor pheromone receptor genes of H. jecorina were transcribed in a strictly mating type dependent manner, but showed enhanced expression levels in the cognate mating type. In the presence of a mating partner under conditions favoring sexual development, transcript levels of pheromone precursors were significantly increased, while those of pheromone receptor genes do not show this trend. In the female sterile T. reesei strain QM6a, transcriptional responses of pheromone precursor and pheromone receptor genes to a mating partner were clearly altered compared to the female fertile wild-type strain CBS999.97. Consequently, a delayed and inappropriate response to the mating partner may be one aspect causing female sterility in QM6a.
Simultaneous powering of forearm pronation and key pinch in tetraplegia using a single muscle-tendon unit (2011)

This study clinically assessed the concept that both thumb flexion and forearm pronation can be restored by brachioradialis (BR)-to-flexor pollicis longus (FPL) tendon transfer if the BR is passed dorsal to the radius. Six patients [two women and four men, mean age 32.3 years (SD 4.9, range 23-56)] underwent BR-to-FPL transfer dorsal to the radius and through the interosseous membrane (IOM). Lateral key pinch strength and pronation range of motion (ROM) were measured 1 year after surgery. A group of six patients [two women and four men, mean age 31.2 years (SD 5.0, range 19-52)] who underwent traditional palmar BR-to-FPL was included for comparison. Postoperative active pronation was significantly greater in the dorsal transfer group compared to the palmar group [149 (SD 6) and 75 (SD 3), respectively] and pinch strength was similar in the two groups [1.28 (SD 0.16) kg and 1.20 (SD0.21) kg, respectively]. We conclude that it is feasible to reconstruct lateral key pinch and forearm pronation simultaneously using only the BR motor.
Cloning of bacteriophage fd gene 2 and construction of a plasmid dependent on fd gene 2 protein. (1981)

Bacteriophage fd gene 2 was cloned in plasmid pBR325. Cells carrying the hybrid plasmid produce about 200 times more enzymatically active fd gene 2 protein than did cells infected with phage fd wild type, as measured by replication of phage fd replicative form I in vitro. Cloned gene 2 supports replication of an artificial phage fd miniplasmid consisting of the origin of bacteriophage fd replication and a gene coding for kanamycin resistance. This plasmid occurs in high copy numbers and is viable only in cells carrying the cloned fd gene 2 or in cells infected with phage fd. Because the miniplasmid is not propagated in natural hosts, it can be considered a safe cloning vector. Its fusion with the gene 2 hybrid plasmid provides an autonomous replicon independent of the polA function of the host cell. fd gene 2 is the only phage-encoded trans-acting function required for replication of double-stranded fd DNA in vivo.
Supplementary Figures 1 - 2 from PD-L1 Expression Is Characteristic of a Subset of Aggressive B-cell Lymphomas and Virus-Associated Malignancies (2023)

&lt;p&gt;PDF file - 1425K, Figure S1. (A) Human placenta stained with the rabbit monoclonal anti-PD-L1 (original lot concentration of 0.22 mg/ml) and showing membrane staining of syncytiotrophoblasts and, (B) the same case stained with the mouse monoclonal anti-PD-L1 (original lot concentration of 0.65 mg/ml). (C) Human tonsil stained with rabbit anti-PD-L1 antibody (original lot concentration of 1.55 mg/ml) and, (D) stained with the rabbit anti-PD-L1 antibody (original lot concentration of 0.22 mg/ml) and, (E) stained with the mouse anti-PD-L1 antibody (original lot concentration of 0.65 mg/ml). Figure S2. (A-C) Case of classical Hodgkin lymphoma stained with (A) the rabbit anti-PD-L1 antibody (original lot concentration of 1.55 mg/ml), (B) the rabbit anti-PD-L1 antibody (original lot concentration of 0.22 mg/ml, and (C) the mouse anti-PD-L1 antibody (original lot concentration of 0.65 mg/ml). (E-F) Case of EBV-negative PTLD stained with (D) the rabbit anti-PD-L1 antibody (original lot concentration of 1.55 mg/ml), (E) the rabbit anti-PD-L1 antibody (original lot concentration of 0.22 mg/ml, and (F) the mouse anti-PD-L1 antibody (original lot concentration of 0.65 mg/ml).&lt;/p&gt;
Inferring tutorial dialogue structure with hidden Markov modeling (2009)

The field of intelligent tutoring systems has seen many successes in recent years. A significant remaining challenge is the automatic creation of corpus-based tutorial dialogue management models. This paper reports on early work toward this goal. We identify tutorial dialogue modes in an unsupervised fashion using hidden Markov models (HMMs) trained on input sequences of manually-labeled dialogue acts and adjacency pairs. The two best-fit HMMs are presented and compared with respect to the dialogue structure they suggest; we also discuss potential uses of the methodology for future work.
Mesoporous Silica Synthesized by Solvent Evaporation:  Spun Fibers and Spray-Dried Hollow Spheres (1997)

Simple synthesis methods for mesoporous fibers and powders by rapid evaporation of hydrolyzed silicon alkoxide−surfactant solutions are described. Mesoporous fibers are prepared by dry spinning, and mesoporous powders by spray drying of alkoxide−surfactant solutions. Precursor solutions, containing fully hydrolyzed tetraethoxysilane, cetyltrimethylammonium chloride surfactant, and, in the case of the fibers, a fiber-forming polymer, in an acidic alcohol/water mixture, are drawn into continuous filaments or atomized into droplets in a heated air stream. During solvent drying, silica and surfactant self-assemble to form the hexagonally ordered mesophase structure, and all of the nonvolatile components (silica, polymer, and surfactant) are incorporated into the mesophase. The pore diameter and surface area of calcined fibers were 20 Å and 1100 m2/g, respectively. For the powders, pore sizes of 25 Å and surface areas as high as 1770 m2/g were measured. Spray-dried powders consisting of hollow spherical particles with mesoporous shells were also produced with this approach.
Pipelined match-lines and hierarchical search-lines for low-power content-addressable memories (2004)

This paper presents a pipelined match-line and a hierarchical search-line architecture to reduce power in content-addressable memories (CAM). The overall power reduction is 60%, with 29% contributed by the pipelined match-lines and 31% contributed by the hierarchical search-lines. This proposed architecture is employed in the design of a 1024/spl times/144 bit ternary CAM, achieving 7 ns search cycle time at 2.89 fJ/bit/search in a 0.18 /spl mu/m CMOS process.