gebhart/patrepeval huggingface dataset:
Highly efficient white organic light-emitting diode (2006)

We present a highly efficient white electroluminescence device by the combination of a solution processed blue organic phosphorescence light-emitting diode with appropriate down-conversion phosphor system. The use of this down-conversion system produced an extraordinary enhancement on device performance, resulting in a white electroluminescence device with luminance efficacy of 25lm∕W at luminance efficiency reaching 39cd∕A. The extraordinary enhancement on device performance is attributed to isotropic radiation pattern of the excited phosphor particles, leading to high light extraction properties.
Nearly complete graphs decomposable into large induced matchings and their applications (2012)

We describe two constructions of (very) dense graphs which are edge disjoint unions of large induced matchings. The first construction exhibits graphs on N vertices with (N2)-o(N2) edges, which can be decomposed into pairwise disjoint induced matchings, each of size N1-o(1). The second construction provides a covering of all edges of the complete graph KN by two graphs, each being the edge disjoint union of at most N2-δ induced matchings, where δ>0.076. This disproves (in a strong form) a conjecture of Meshulam, substantially improves a result of Birk, Linial and Meshulam on communicating over a shared channel, and (slightly) extends the analysis of Hastad and Wigderson of the graph test of Samorodnitsky and Trevisan for linearity. Additionally, our constructions settle a combinatorial question of Vempala regarding a candidate rounding scheme for the directed Steiner tree problem.
Breaking the diffraction limit of light sheets allows fast isotropic imaging of large samples by ultramicroscopy (2018)

By breaking the diffraction limit of light sheets of low numerical aperture (NA) we were able to generate extremely long thin sheets of light with a thickness in the one micron range and a vastly increased Rayleigh range. We measured the thickness of the light sheets with different methods including standard point spread function measurement with beads. By using these light sheets in our ultramicroscope fast 3D imaging of whole mouse brains with objectives with a large field of view was possible. Due to the extremely low divergence of the light sheets mouse brains could be reconstructed from a single stack of optical sections with isotropic resolution. The light sheets used were essentially non-Gaussian generated by new optics we developed. Compared to a Gaussian light sheet of the same NA our new light sheet is much thinner. Thus the diffraction limit which holds also for low NA Gaussian light sheets was significantly surpassed. These optics will allow the application of ultramicroscopy to ever increasing samples beyond the whole mouse brain range.
Structural dynamics of cereal mitochondrial genomes as revealed by complete nucleotide sequencing of the wheat mitochondrial genome (2005)

The application of a new gene-based strategy for sequencing the wheat mitochondrial genome shows its structure to be a 452 528 bp circular molecule, and provides nucleotide-level evidence of intra-molecular recombination. Single, reciprocal and double recombinant products, and the nucleotide sequences of the repeats that mediate their formation have been identified. The genome has 55 genes with exons, including 35 protein-coding, 3 rRNA and 17 tRNA genes. Nucleotide sequences of seven wheat genes have been determined here for the first time. Nine genes have an exon-intron structure. Gene amplification responsible for the production of multicopy mitochondrial genes, in general, is species-specific, suggesting the recent origin of these genes. About 16, 17, 15, 3.0 and 0.2% of wheat mitochondrial DNA (mtDNA) may be of genic (including introns), open reading frame, repetitive sequence, chloroplast and retro-element origin, respectively. The gene order of the wheat mitochondrial gene map shows little synteny to the rice and maize maps, indicative that thorough gene shuffling occurred during speciation. Almost all unique mtDNA sequences of wheat, as compared with rice and maize mtDNAs, are redundant DNA. Features of the gene-based strategy are discussed, and a mechanistic model of mitochondrial gene amplification is proposed.
High‐resolution nuclear magnetic resonance spectroscopy of biological tissues using projected magic angle spinning (2005)

High-resolution NMR spectra of materials subject to anisotropic broadening are usually obtained by rotating the sample about the magic angle, which is 54.7 degrees to the static magnetic field. In projected magic angle spinning (p-MAS), the sample is spun about two angles, neither of which is the magic angle. This provides a method of obtaining isotropic spectra while spinning at shallow angles. The p-MAS experiment may be used in situations where spinning the sample at the magic angle is not possible due to geometric or other constraints, allowing the choice of spinning angle to be determined by factors such as the shape of the sample, rather than by the spin physics. The application of this technique to bovine tissue samples is demonstrated as a proof of principle for future biological or medical applications.
X-ray diffraction determination of the interface structure of CdSe/BeTe superlattices (2003)

Structural study of CdSe/BeTe superlattices (SLs) grown by molecular beam epitaxy on GaAs substrate was performed by using double and triple crystal x-ray diffractometry. The period of the studied structures was about 5 nm, while the thickness of thin CdSe insertions varied from 0.4 to 1.5 monolayer. It is shown that new Be–Se bonds arise at the BeTe–CdSe interfaces in addition to the Be–Se bonds expected at the CdSe–BeTe interfaces. From the analysis of the diffraction curves of 002-reflection the complex composition of interfaces and thin insertions has been determined and contribution of all types of bonds in each SL period calculated. The diffraction curves of 004-reflection were used for the specification of the fine structure of the interfaces.
Towards secure resource sharing for impromptu collaboration in pervasive computing (2007)

Access control in mobile and pervasive computing is a complex issue, with many aspects relating to the establishment, management, and enforcement of methods and policies that allow mobile devices to share resources with each other. Communication between mobile devices can arise spontaneously, involve the sharing of few resources between heterogeneous platforms, and only need to be maintained for a short time. Additionally, the devices often communicate with each other a single time, and have no pre-shared secret or a priori knowledge of the other device. In this paper we propose a secure solution for providing controlled access to local resources in mobile and pervasive computing environments. Our solution incorporates demonstrative verification of security credentials, a key-based capability delegation, and easy to use access control features in order to provide simple access with low maintenance costs. It is particularly designed for one-time-only communication between mobile-to-mobile or mobile-to-kiosk devices.
Population-based incidence trends of oropharyngeal and oral cavity cancers by sex among the poorest and underprivileged populations (2014)

We report on SES disparities in oral cancer, emphasizing the need for community-based interventions that address access to medical care and the distribution of educational and health promotion resources among the most SES deprived communities in British Columbia.
Thiol-mediated Oxidation of Nonphenolic Lignin Model Compounds by Manganese Peroxidase of Phanerochaete chrysosporium (1989)

In the presence of MnII, H2O2, and glutathione (GSH), manganese peroxidase oxidized veratryl alcohol (I) to veratraldehyde (IV). Anisyl alcohol (II) and benzyl alcohol (III) were also oxidized by this system to their corresponding aldehydes (V and VI). In the presence of GSH, chemically prepared MnIII or gamma-irradiation also catalyzed the oxidation of I, II, and III to IV, V, and VI, respectively. GSH and dithiothreitol rapidly reduced MnIII to MnII in the absence of aromatic substrates and the dithiothreitol was oxidized to its disulfide (4,5-dihydroxyl-1,2-dithiane). These results indicate that the thiol is oxidized by enzyme-generated MnIII to a thiyl radical. The latter abstracts a hydrogen from the substrate, forming a benzylic radical which reacts with another thiyl radical to yield an intermediate which decomposes to the benzaldehyde product. In the presence of MnII, GSH, and H2O2, manganese peroxidase also oxidized 1-(4-ethoxy-3-methoxy-phenyl)-2-(4'-hydroxymethyl-2'-methoxyphenoxy)- 1,3-dihydroxypropane (XII) to yield vanillyl alcohol (VII), vanillin (VIII), 1-(4-ethoxy-3-methoxyphenyl)-1,3-dihydroxypropane (XVI), 1-(4-ethoxy-3-methoxyphenyl)-1-oxo-3-hydroxypropane (XIX), and several C alpha oxidized dimeric products. Abstraction of the C alpha (A ring) hydrogen of the dimer (XII) yields a benzylic radical, leading to C beta oxygen ether cleavage. The resultant intermediates yield the ketone (XIX) and vanillyl alcohol (VII) or vanillin (VIII). Alternatively, benzylic radical formation at the C' alpha position (B ring) leads to radical cleavage, yielding a quinone methide and a C beta radical, which yield vanillin and the 1,3-diol (XVI), respectively. In these reactions, MnIII oxidizes a thiol to a thiyl radical which subsequently abstracts a hydrogen from the substrate to form a benzylic radical. The latter undergoes nonenzymatic reactions to yield the final products.
Immuno-stimulating Activities of Polysaccharide Fractions Isolated from Persimmon Leaves (2012)

In order to develop new physiologically active polysaccharides from persimmon leaves, two different crude polysaccharides were prepared using hot water (PLW-0) and pectinase digestion (PLE-0) and their immuno-stimulating activities were estimated. PLW-0 and PLE-0 showed similar sugar compositions with 15 different sugars, including rarely observed sugars in general polysaccharides such as 2-O-methyl-fucose, 2-O-methyl-xylose, apiose, aceric acid, 3-deoxy-D-manno-2-octulosonic acid, and 3-deoxy-D-lyxo-2-heptulosaric acid, but the uronic acid content of PLE-0 was lower than that of PLW-0 caused by pectinase treatment. Both PLW-0 and PLE-0 showed potent anti-complementary activity in a dose-dependent manner which was similar to a known immuno-stimulating polysaccharide, PSK, from Coriolus versicolor. The activity of PLE-0 at a low concentration (<TEX>$100{\mu}g/m{\ell}$</TEX>) was higher than that of PLW-0. In an in vitro cytotoxicity analysis, PLW-0 and PLE-0 (up to <TEX>$1,000{\mu}g/m{\ell}$</TEX>) did not affect the growth of peritoneal macrophages and Colon 26-M3.1 carcinoma cells. In contrast, they enhanced lymphocyte proliferation activity. Peritoneal macrophages stimulated with PLW-0 and PLE-0 produced various cytokines, such as IL-6 and IL-12. However, PLE-0 was more effective on the cytokine production. Intravenous administration of PLW-0 and PLE-0 significantly augmented natural killer (NK) cell cytotoxicity against Yac-1 tumor cells 3 days after the treatment of polysaccharide fractions. But NK cells obtained from the PLE-treated group showed higher tumoricidal activity even at a low dose of <TEX>$40{\mu}g$</TEX>/mouse. In experimental lung metastasis of Colon 26-M3.1 carcinoma cells, prophylactic administration of PLW-0 and PLE-0 significantly inhibited lung metastasis in a dose-dependent manner and PLE-0 was more effective on the inhibition of cancer metasasis. The results lead us to conclude that the pectinase-treated process is indispensable to preparing polysaccharides with higher immune-stimulating activity from persimmon leaves.
Presentation of AMI—Symptoms, Examination, Biomarkers and Atypical Presentations (2010)

Prevalence and Incidence The global burden of cardiovascular disease is immense, and it remains the principal cause of mortality worldwide. Coronary heart disease mortality showed a rapid rise after the 2nd World War reaching a peak around 1970. Still it is estimated that 12 millions deaths will be attributable to CHD in the year 2020. Annual coronary event rates differ greatly between countries ranging from 60/100,000 in China to &gt;400/100,000 in the United Kingdom (1).
The impact of anthropomorphic indices on clinical outcomes in patients with acute ST-elevation myocardial infarction (2006)

Although statistically significantly related to most outcomes in patients with STEMI including death and shock, body weight provided clinically relevant prognostic information only for the risk of major bleeding and of stroke. Furthermore, BMI or BSA contributed little incremental prognostic information beyond that provided by weight alone. Thus, the existing large body of information concerning the strong prognostic importance of anthropometric measures with outcomes after STEMI should be interpreted in the context of other more important risk factors.
Formation and reduction of pyramidal hillocks on m-plane {11¯00} GaN (2007)

Surface morphology and hillock reduction were studied on m-plane {11¯00} n-type GaN films and light emitting diode structures grown by metal organic chemical vapor deposition on low defect-density m-plane GaN substrates. For nominally on-axis m-plane films, predominantly pyramidal hillocks were observed, which were composed of two faces symmetrically inclined by 0.1°–0.25° to the ±[112¯0] a direction and two faces inclined by 0.5°–0.95° to the [0001¯] c− and the [0001] c+ directions, respectively. All faces of the pyramidal hillocks for the nominally on-axis GaN films had clearly defined step-terrace structures. Gradual changes in nominal miscut angles from 0° to 10° along the a and the c− directions succeeded in a continuous hillock reduction yielding atomically flat surfaces.
Roles of Sema4D and Plexin-B1 in tumor progression (2010)

Sema4D, also known as CD100, is a protein belonging to class IV semaphorin. Its physiologic roles in the immune and nervous systems have been extensively explored. However, the roles of Sema4D have extended beyond these traditionally studied territories. Via interaction with its high affinity receptor Plexin-B1, Sema4D-Plexin-B1 involvement in tumor progression is strongly implied. Here, we critically review and delineate the Sema4D-Plexin-B1 interaction in many facets of tumor progression: tumor angiogenesis, regulation of tumor-associated macrophages and control of invasive growth. We correlate the in vitro and in vivo experimental data with the clinical study outcomes, and present a molecular mechanistic basis accounting for the intriguingly contradicting results from these recent studies.
Ractopamine induces differential gene expression in porcine skeletal muscles1 (2007)

Ractopamine (RAC) improves growth by increasing lean accretion and decreasing fat deposition through repartitioning nutrients from adipose tissue to skeletal muscle. Although the process is not completely understood, RAC alters the proportion of muscle fiber type composition toward a faster-contracting phenotype. Because one of the primary determinants of contractile speed is the relative abundance of myosin heavy chain (MyHC) isoforms and because the genes encoding these isoforms are transcriptionally regulated, RAC likely alters MyHC gene expression. Using real-time PCR, the relative abundance of transcripts of individual type I, IIA, IIX, and IIB, and total MyHC, as well as glycogen synthase, citrate synthase, lactate dehydrogenase, peroxisome proliferator activated receptor alpha, beta1-adrenergic receptor (AR), and beta2-AR were determined in the LM of 44 pigs fed RAC (20 mg/kg) for 0, 1, 2, or 4 wk. In addition, MyHC isoform expression was determined in the LM and red semitendinosus and white semitendinosus muscles of 48 pigs fed RAC (20 mg/kg) for shorter periods of 12, 24, 48, or 96 h. Type I MyHC expression was unaffected (P > 0.73) by RAC administration. Type IIA MyHC expression decreased (P < 0.0001) by 96 h, was lower (P < 0.0001) by 1 wk, and returned to normal by 4 wk. Type IIX MyHC mRNA decreased (P < 0.001) by 2 wk and continued to decrease (P < 0.0001) by 4 wk. Most interesting was an increase (P < 0.0001) in type IIB MyHC by 12 h, which was maintained at an elevated level throughout the 4-wk feeding period. Abundance of glycogen synthase transcript was increased (P < 0.05) by 12 h, but was not different from controls at 2 wk, and was lower (P < 0.01) at 4 wk. Gene expression of beta1-AR was not affected by feeding RAC, whereas beta2-AR gene expression was decreased (P < 0.05) by 2 wk. These data show MyHC genes are differentially regulated by RAC and suggest that the beta adrenergic agonist-induced repartitioning effect is, in part, mediated by changing muscle fiber type-specific gene expression, perhaps through the beta2-AR.
Targeting Acidity in Pancreatic Adenocarcinoma: Multispectral Optoacoustic Tomography Detects pH-Low Insertion Peptide Probes In Vivo (2015)

Compared with pH-insensitive controls, V7-750 pH-sensitive probe specifically targets pancreatic adenocarcinoma and has minimal off-target accumulation. The noninvasive detection of pH-targeted probes by means of MSOT represents a promising modality to improve the detection and monitoring of pancreatic cancer.
Persistence and Biological Reactions of Pesticides in Soils (1965)

Abstract Although microorganisms are often considered to be omnivorous and biochemically omnipotent, they seem unable to destroy at significant rates many synthetic chemicals that enter soil. This unexplained microbial fallibility recently has assumed prominence because of the long persistence of a variety of pesticides. With at least certain compounds, the chemical, physiological, or environmental basis of the biological failings can be established, as illustrated with substituted phenols and phenoxy herbicides. Microorganisms may detoxify pesticide‐treated soil by metabolizing or degrading the added substance. The microflora may also be responsible for the generation of a toxic condition in soil by activation of the applied pest‐control agent. The use of laboratory precedents as guides in investigations of natural transformations is considered, and instances of pesticide metabolism in soil are cited.
On the Integration of Acoustics and LiDAR: a Multi-Modal Approach to Acoustic Reflector Estimation (2022)

Having knowledge on the room acoustic properties, e.g., the location of acoustic reflectors, allows to better reproduce the sound field as intended. Current state-of-the-art methods for room boundary detection using microphone measurements typically focus on a two-dimensional setting, causing a model mismatch when employed in real-life scenarios. Detection of arbitrary reflectors in three dimensions encounters practical limitations, e.g., the need for a spherical array and the increased computational complexity. Moreover, loudspeakers may not have an omnidirectional directivity pattern, as usually assumed in the literature, making the detection of acoustic reflectors in some directions more challenging. In the proposed method, a LiDAR sensor is added to a loudspeaker to improve wall detection accuracy and robustness. This is done in two ways. First, the model mismatch introduced by horizontal reflectors can be resolved by detecting reflectors with the LiDAR sensor to enable elimination of their detrimental influence from the 2D problem in pre-processing. Second, a LiDAR-based method is proposed to compensate for the challenging directions where the directive loudspeaker emits little energy. We show via simulations that this multi-modal approach, i.e., combining microphone and LiDAR sensors, improves the robustness and accuracy of wall detection.
Curaua fibers - The queen of the fibers (2017)

Nowadays, the usage of natural resources is under worldwide growing interest. From this perspective, different renewable sources have been studied to replace man-made polymers or even improve the properties of current materials. Considering these aspects, natural fibers appear as a great opportunity and among them curaua (Ananas erectifolius L. B. Smith) fiber has unique properties such as high strength, low density, high fineness and high cellulose content. In addition, due to their mechanical properties and recyclability, it has become a fiber of great interest for developing composites materials. Due to its high cellulose content, curaua fiber is an important potencial source of raw material for producing nanocellulose that can be used to manufacture nanocomposites.
Heart rate estimation from dual pressure sensors of a dialysis machine (2015)

Dialysis patients often suffer from cardiovascular diseases, motivating the use of continuous monitoring of cardiac activity in clinical routine. Cardiac pressure pulses propagate through the vascular system and enter the extracorporeal blood circuit of a dialysis machine, where the pulses are captured by pressure sensors. The cardiac pulses are obscured by the much stronger pressure pulses originating from the peristaltic blood pump. We have previously shown that a cardiac signal can be extracted from the venous pressure signal. However, that method has been found to perform less well at very low cardiac pressure pulse amplitudes. In the present study, we propose a novel method which addresses this issue by using the signals from both the arterial and the venous pressure sensors. The method is compared to the previous method on clinical data using a photoplethysmogram as reference. The results suggests that heart rate can be estimated more accurately from pressure signals with lower cardiac signal amplitude when both arterial and venous pressure are used, compared to when only the venous signal is used.
Advancing the application of planar chalcogenides (2004)

Human mAb 54G10 has broad neutralizing activity against HMPV and could have prophylactic and therapeutic utility clinically. The conserved epitope could represent a structural vaccine target for HMPV and RSV.
Effect of green tea polyphenols and Tai Chi exercise on bone health in postmenopausal women with low bone mass: a 24-week placebo-controlled randomized trial (2011)

Osteoporosis is a major health problem in postmenopausal women. This study evaluated the effects of green tea polyphenols (GTP) supplementation and Tai Chi exercise (TC) on bone health and related ...
Fabrication, characterization and modelling of multilayered cantilevers with piezoelectric AlN ceramic as actuator (2007)

Colloque avec actes et comité de lecture. Internationale.
Cytolytic Virus Activation Therapy for Epstein-Barr Virus–Driven Tumors (2012)

Our results in the initial CLVA-treated patients indicate that the therapy had a biological effect and was well tolerated with only moderate transient toxicity. This new virus-specific therapy could open a generic approach for treatment of multiple EBV-associated malignancies.