gebhart/patrepeval huggingface dataset:
Discrimination of two methylene groups in non‐symmetric succinate esters in sesquiterpene dimers by heteronuclear 13C{1H}NOE spectroscopy (1995)

Abstract In the assignment of the non‐equivalent methylene group of an asymmetric succinate residue in the macrocyclic lactone ring of shizukaols B and F, isolated from Chloranthus japonicus , distinction of two‐bond C—H and three‐bond C—H was needed. The steady state and transient 13 C{ 1 H}NOE was used to detect two‐bond C‐H. One pair of non‐equivalent methylene protons was saturated simultaneously by quasi‐simultaneous irradiation. Inversion of two protons whose chemical shifts were close was carried out by a squared pulse, and inversion of two protons whose chemical shifts were far from each other was performed using a double DANTE pulse train.
Application of XUV interferometry to the determination of the temporal coherence of X-ray lasers (2005)

International audience
Intraarticular injections of hyaluronan in patients with cartilage abnormalities and knee pain (1994)

The effects of intraarticular hyaluronan do not differ significantly from those of placebo in patients with knee pain and cartilage disease.
Deformable Spatial Pyramid Matching for Fast Dense Correspondences (2013)

We introduce a fast deformable spatial pyramid (DSP) matching algorithm for computing dense pixel correspondences. Dense matching methods typically enforce both appearance agreement between matched pixels as well as geometric smoothness between neighboring pixels. Whereas the prevailing approaches operate at the pixel level, we propose a pyramid graph model that simultaneously regularizes match consistency at multiple spatial extents-ranging from an entire image, to coarse grid cells, to every single pixel. This novel regularization substantially improves pixel-level matching in the face of challenging image variations, while the "deformable" aspect of our model overcomes the strict rigidity of traditional spatial pyramids. Results on Label Me and Caltech show our approach outperforms state-of-the-art methods (SIFT Flow [15] and Patch-Match [2]), both in terms of accuracy and run time.
E-infocenter, Una herramienta visual para la gestión de proyectos en robótica educativa usando tecnologías web (2012)

Las tecnologías como Internet y la robótica educativa, caracterizadas por ser relativamente nuevas y motivadoras, son el escenario ideal para la aplicación de los métodos activos de enseñanza, tal es el caso del aprendizaje basado en proyectos. La realización de proyectos con robots apoyados por el entorno colaborativo de la Web 2.0, puede ayudar al alumnado a desarrollar una serie de competencias transferibles al ámbito laboral. En este artículo se describe el proceso de selección, diseño e implementación de una herramienta visual en línea denominada E-infocenter para la gestión de proyectos. Esta herramienta ha sido utilizada por primera vez durante seis semanas en el Taller Vehicles NXT con robots LEGO, dirigido a niños de edades comprendidas entre 8 y 15 años. Los beneficios percibidos por los participantes han sido a nivel de gestión, emocional y de colaboración.
Correlation and keying of Rayleigh scatter for loss and temperature sensing in parallel optical networks (2004)

We develop a method by which coherent optical frequency domain reflectometry (OFDR) can be used to key portions of optical fiber by measuring their complex Rayleigh backscatter signatures. We show that these complex keys can be used to locate specific fiber lengths embedded within a parallel optical network, and that they can further be used to interrogate any induced loss or temperature change in the identified portion of the network.
Synthesis of pure blue emissive poly(2,7‐carbazole)s anchored by electron donor pendant (2019)

ABSTRACT Three novel poly(2,7‐carbazole)s having hole injection and transporting pendent moieties of carbazole and triphenylamine at the N ‐position were synthesized for achieving pure blue electroluminescence. The N ‐pendants in the polymers correspond to N ‐phenylcarbazol‐2‐yl ( P1 ), N , N ‐diphenylamino‐ N ‐phenylcarabazol‐2‐yl ( P2) , and 4‐phenyl having a hydrocarbon chain with a triphenylamine terminal ( P3 ), respectively. Electronic, optical, and electroluminescence properties of these polymers were compared with those of a poly(2,7‐carbazole) directly connected with triphenylamine at the N ‐position ( P0 ) having an aggregation‐induced emissive property. The photoluminescence (PL) spectra suggested that they could emit in the region of blue light in the film state. Especially, P2 that has the fixed and large diphenylaminocarbazolyl pendant showed a deep‐blue fluorescence with CIE( x , y ) = (0.15, 0.07). The P0 , P2 , and P3 based light emitting diode devices showed maximum electroluminescence wavelengths in the range of 430–450 nm. The P2 device showed pure blue emission (CIE[ x , y ] = [0.18, 0.16]), high luminance (1130 cd/m 2 ) and current density (628 mA/cm 2 ) at 8 V, whereas low‐energy emissions around 500–600 nm were emerged at higher than 9 V. The P0 and P3 devices also showed a blue electroluminescence in the range of 8–11 V, but their luminance and efficiency were low. © 2019 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2019 , 57 , 2526–2534
The Effect of Prenatal Protein-Energy Malnutrition on Collagen Metabolism in Fetal Bones (1989)

We analyzed various biochemical variables of the bones in fetal rats whose dams were protein-energy malnourished. Dams were randomly divided into two groups and fed either a 6% protein diet as a malnourished group or a 20% protein diet as a control, from day 13 of gestation to day 22, when fetuses were removed. Hexosamine and hydroxyproline contents of the calvaria and hexosamine contents of long bones were greater in the malnourished group than in the controls. Sequential extractability of collagen differed among various bones in the malnourished group and controls. The ratio of alpha:beta obtained from SDS-polyacrylamide gel of neutral salt-soluble collagen tended to increase in the long bones and mandible, and decrease in the calvaria and ribs in the malnourished group. Also, the ratio of alpha 1:alpha 2 tended to be lower in the malnourished group than in the control group in all bones. Protein-energy malnutrition during pregnancy has shown to affect biochemical composition of various fetal bones.
Supplementary Tables 1-2 from Therapeutic Synergy between microRNA and siRNA in Ovarian Cancer Treatment (2023)

&lt;p&gt;Supplementary Tables 1-2 - PDF file 85K, MicroRNAs significantly associated with overall survival and response to therapy in ovarian cancer patients using TCGA 2009 database (Table S1) and Clinical and bio-pathological features of the 91 MDACC ovarian cancer samples used in the study (Table S2)&lt;/p&gt;
ChemInform Abstract: Electrical Conductivity in Solid Solutions of La5‐xMxMo3O16.5+x/2 (M: Ce4+ and Th4+; 0.0 ≤ x < 0.3) with a Fluorite‐Related Structure. (1990)

Abstract The title solid solutions, all having a CaF 2 ‐related structure (La 5 Mo 3 O 16.5 : space group Pn3n, Z=4) are prepared by solid state reactions of MO 2 (M: Ce, Th), MoO 2 , MoO 3 , and La 2 O 3 at 960 °C (evacuated silica tube, 3 d).
Orchiectomy or androgen receptor blockade attenuates baroreflex-mediated bradycardia in conscious rats (2006)

The data suggest: 1) Androgen depletion or adequate androgen receptor blockade attenuates baroreflex bradycardia. 2) The reflex increase in serum testosterone may counterbalance the action of the lower doses (5 or 15 mg kg(-1)) of flutamide. 3) The absence of a change in serum 17beta-estradiol rules out its contribution to flutamide action on baroreflex bradycardia.
Very low frequency piezoelectric energy harvester designed for heart beat vibration scavenging (2013)

National audience
Educating medical trainees on medication reconciliation: a systematic review (2015)

Varying success was achieved with medication reconciliation education interventions. While some noted improved competence and/or confidence amongst trainees, namely undergraduate medical students, others noted little effect resulting from the intervention.
New Periodicals of 1959--Part II (1960)

A s USUAL, the concluding list of peri- odicals whose publication began in 1959 is larger than the initial list. While emphasis seemingly has shifted from atomic energy and automation, for example, to general cultural publications and to a recognition and study of national problems, this shift may be partially due to the annual inclusive scope of the final list. The range is quite wide, indeed even almost in defiance of a classification by groups.
Effect of Antibiotics on Enterocystoplasty Urinary Nitrosamine Levels (2002)

No AccessJournal of UrologyUROLOGICAL SURVEY: Infection and Inflammation of the Genitourinary Tract: Abstracts1 Jul 2002Effect of Antibiotics on Enterocystoplasty Urinary Nitrosamine Levels Anthony J. SchaefferM.D. Anthony J. SchaefferAnthony J. Schaeffer More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)64966-XAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Effect of Antibiotics on Enterocystoplasty Urinary Nitrosamine Levels." The Journal of Urology, 168(1), pp. 397–398 © 2002 by American Urological Association, Inc.FiguresReferencesRelatedDetails Volume 168Issue 1July 2002Page: 397-398 Advertisement Copyright & Permissions© 2002 by American Urological Association, Inc.MetricsAuthor Information Anthony J. Schaeffer More articles by this author Expand All Advertisement PDF DownloadLoading ...
Investigation of the Formation of Squalene Oligomers Exposed to Ultraviolet Light and Changes in the Exposed Squalene as a Potential Skin Model (2022)

UV-induced oligomerisation of squalene was undertaken to indicate the potential for squalene-containing biological systems to exhibit rheology changes. DOSY NMR enabled the determination of the molecular weight (MW) range using Stokes-Einstein Gierer-Wirtz Estimation (SEGWE Calculator, University of Manchester). This approach was validated by Atmospheric Solids Analysis Probe Time of Flight Mass Spectrometry (ASAP TOF MS). To demonstrate the principle, both benzoyl peroxide and AIBN were used, separately, to initiate rapid, radical oligomerisation. Subsequent experiments in the absence of initiators compared the influence of UV wavelength and time on the resulting oligomer formation. To further model a relevant biological implication of this potentially chaotic UV oligomerisation, both saturated and unsaturated free fatty acids were added to squalene and exposed to UV at 285 nm and 300 nm to determine if cross oligomerisation could be observed. This representation of sebum evidenced the formation of a distribution of higher MW oligomers. Internal viscosity was normalised using the DMSO solvent, but to confirm that changes in rheology did not affect diffusion, a final experiment where fresh squalene was added to our oligomer mixture, representative of sebum, showed that unchanged squalene possessed the anticipated monomeric diffusion coefficient and hence MW. This work suggests, at least qualitatively, that UV-induced squalene oligomerisation can occur over time and that this may have a role in the behaviour of squalene on the skin.
CuH-Catalyzed Asymmetric Reduction of α,β-Unsaturated Carboxylic Acids to β-Chiral Aldehydes (2018)

The copper hydride (CuH)-catalyzed enantioselective reduction of α,β-unsaturated carboxylic acids to saturated aldehydes is reported. This protocol provides a new method to access a variety of β-chiral aldehydes in good yields, with high levels of enantioselectivity and broad functional group tolerance. A reaction pathway involving a ketene intermediate is proposed based on preliminary mechanistic studies and density functional theory calculations.
Electronic Energies of Interaction of Point Defects with Interfaces and Grain Boundaries (1992)

The electronic energies of interaction of a point defect with interfaces and grain boundaries are calculated, as a function of the distance x03 between the point defect and the corresponding planar defect. These interaction energies are shown to have the same type of oscillations as the corresponding local electronic densities. Therefore the electronic interactions more significantly affect the energy of segregation of point defects towards interfaces when x03 is in the near vicinity of these interfaces, while at large distances the contribution of elastic interactions can dominate.
Mass spectrometric multiple soil-gas flux measurement system with a portable high-resolution mass spectrometer (MULTUM) coupled to an automatic chamber for continuous field observations (2020)

Abstract. We developed a mass spectrometric soil-gas flux measurement system using a portable high-resolution multi-turn time-of-flight mass spectrometer, called MULTUM, and we combined it with an automated soil-gas flux chamber for the continuous field measurement of multiple gas concentrations with a high temporal resolution. The developed system continuously measures the concentrations of four different atmospheric gases (NO2, CH4, CO2, and field soil–atmosphere flux measurements of greenhouse gases (NO2, O2) ranging over 6 orders of magnitude at one time using a single gas sample. The measurements are performed every 2.5 min with an analytical precision (2 standard deviations) of ±34 ppbv for NO2; ±170 ppbv, CH4; ±16 ppmv, CO2; and ±0.60 vol %, O2 at their atmospheric concentrations. The developed system was used for the continuous field soil–atmosphere flux measurements of greenhouse gases (NO2, CH4, and CO2) and O2 with a 1 h resolution. The minimum quantitative fluxes (2 standard deviations) were estimated via a simulation as 70.2 µgNm-2h-1 for NO2; 139 µgCm-2h-1, CH4; 11.7 mg C m−2 h−1, CO2; and 9.8 g O2 m−2 h−1, O2. The estimated minimum detectable fluxes (2 standard deviations) were 17.2 µgNm-2h-1 for NO2; 35.4 µgCm-2h-1, CH4; 2.6 mg C m−2 h−1, CO2; and 2.9 g O2 m−2 h−1, O2. The developed system was deployed at the university farm of the Ehime University (Matsuyama, Ehime, Japan) for a field observation over 5 d. An abrupt increase in NO2 flux from 70 to 682 µgNm-2h-1 was observed a few hours after the first rainfall, whereas no obvious increase was observed in CO2 flux. No abrupt NO2 flux change was observed in succeeding rainfall events, and the observed temporal responses at the first rainfall were different from those observed in a laboratory experiment. The observed differences in temporal flux variation for each gas component show that gas production processes and their responses for each gas component in the soil are different. The results of this study indicate that continuous multiple gas concentration and flux measurements can be employed as a powerful tool for tracking and understanding underlying biological and physicochemical processes in the soil by measuring more tracer gases such as volatile organic carbon, reactive nitrogen, and noble gases, and by exploiting the broad versatility of mass spectrometry in detecting a broad range of gas species.
Simultaneous Chemical Vapor Deposition of SiC-Dispersed Phase Composites (2008)

Ceramic composite are being developed because they can have high strength and toughness yet retain the normal ceramic attributes of refractoriness and high resistance to abrasion and corrosion. In the present research, toughened ceramic composites were produced by the simultaneous chemical vapor deposition of an SiC matrix and a dispersed phase of TiSi2 The morphology of the dispersed phase was found to control the mechanical properties of the composite. Deposition of coatings in afluidized bed produced a finer and more uniformly dispersed second phase. The conditions within the fluidized bed, such as temperature, gas composition, and hydrogen flow also affected the morphology of the TiSi2 phase. The fracture toughness values for these composite coatings approached 5.5 MPa √m at 25°C, which is significantly higher than the toughness value for chemically vapor-deposited SiC.
BioTAP‐XL: Cross‐linking/Tandem Affinity Purification to Study DNA Targets, RNA, and Protein Components of Chromatin‐Associated Complexes (2015)

In order to understand how chromatin complexes function in the nucleus, it is important to obtain a comprehensive picture of their protein, DNA, and RNA components, as well as their mutual interactions. This unit presents a chromatin cross-linking approach (BioTAP-XL) that utilizes a special BioTAP-tagged transgenic protein bait along with mass spectrometry to identify protein complex components, and high-throughput sequencing to identify RNA components and DNA binding sites. Full protocols are provided for Drosophila cells and for human cells in culture, along with an additional protocol for Drosophila embryos as the source material. A key element of the approach in all cases is the generation of control data from input chromatin samples.
Regulating online video content: models and issues (2021)

What will the regulation of the next generation of video media look like? None of the traditional societal objectives will vanish. Instead, they will adjust the tools to the new environment. In addition, the new online video medium creates new issues. The chapter analyzes the likely applicability of several past regulatory models that have co-existed, such as the print model, the TV model, the public broadcast model, the film model, the telecom model, and the computer layer model. It then proceeds to several policy issues relevant to content identified in the preceding chapters. It looks at several regulatory options to each of these issues, and the most likely direction. The issues of content include support of national culture through ownership rules, import quotas, and various public support mechanisms. Other issues are the protection of societal values (children, hate speech, information integrity, algorithms, privacy, intellectual property, and affordability).
Synthesis of novel 6-enaminopurines (2004)

Two different approaches have been used for the synthesis of 6-enaminopurines 6 from 5-amino-4-cyanoformimidoyl imidazoles. In the first approach imidazoles 1 were reacted with ethoxymethylenemalononitrile or ethoxymethylenecyanoacetate under mild experimental conditions and this led to 9-substituted-6-(1-amino-2,2-dicyanovinyl) purines 6a-f or 9-substituted-6-(1-amino-2-cyano-2-methoxycarbonylvinyl) purines 6g-k. These reactions are postulated to occur through an imidazo-pyrrolidine intermediate 7, which rapidly rearranges to the 6-enaminopurine 6. In the second approach 6-methoxyformimidoyl purines 3, prepared in two efficient steps from 5-amino-4-cyanoformimidoyl imidazoles 1, were reacted with malononitrile and methylcyanoacetate with a mild acid catalysis (ammonium acetate or piperidinium acetate) to give 6-enaminopurines 6a, 6d, 6f, 6g and 6k in very good yields. Only low yields were obtained for the 6-enaminopurine 6j, as competing nucleophilic attack on C-8 of either 3d or 6jcauses ring opening with formation of pyrimido-pyrimidines 11 and 10a respectively.
Horizontal resonant frequencies of vibration pickup on soil surfaces (1979)

A vibration pickup set on a soil surface has a resonant frequency caused by the mass of the pickup and the contact compliance of a setting point. The resonant frequency produced in the measurement system causes the errors in measurement and places restrictions on the measurement frequency range. This paper gives the characteristics of the horizontal resonant frequency and also derives expressions for a coupled motion of the vibration pickup model set on an elastic half-space. It is shown graphically, by an example, that the height of the center of gravity and the contact areas of the pickup have considerable effects upon the horizontal resonant frequency. The derived solutions, which are approximately represented as the function of resonant frequency and the frequency of an exciting force, provide adequate accuracy for engineering analysis to the footings of little bodies.
Efficiency Enhancement of Pico-cell Base Station Power Amplifier MMIC in GaN HFET Technology Using the Doherty Technique (2012)

With the growth of smart phones, the demand for more broadband, data centric technologies are being driven higher. As mobile operators worldwide plan and deploy 4th generation (4G) networks such as LTE to support the relentless growth in mobile data demand, the need for strategically positioned pico-sized cellular base stations known as ‘pico-cells’ are gaining traction. In addition to having to design a transceiver in a much compact footprint, pico-cells must still face the technical challenges presented by the new 4G systems, such as reduced power consumptions and linear amplification of the signals. The RF power amplifier (PA) that amplifies the output signals of 4G pico-cell systems face challenges to minimize size, achieve high average efficiencies and broader bandwidths while maintaining linearity and operating at higher frequencies. 4G standards as LTE use non-constant envelope modulation techniques with high peak to average ratios. Power amplifiers implemented in such applications are forced to operate at a backed off region from saturation. Therefore, in order to reduce power consumption, a design of a high efficiency PA that can maintain the efficiency for a wider range of radio frequency signals is required. The primary focus of this thesis is to enhance the efficiency of a compact RF amplifier suitable for a 4G pico-cell base station. For this aim, an integrated two way Doherty amplifier design in a compact 10mm x 11.5mm monolithic microwave integrated circuit using GaN device technology is presented. Using non-linear GaN HFETs models, the design achieves high effi-ciencies of over 50% at both back-off and peak power regions without compromising on the stringent linearity requirements of 4G LTE standards. This demonstrates a 17% increase in power added efficiency at 6 dB back off from peak power compared to conventional Class AB amplifier performance. Performance optimization techniques to select between high efficiency and high linearity operation are also presented. Overall, this thesis demonstrates the feasibility of an integrated HFET Doherty amplifier for LTE band 7 which entails the frequencies from 2.62-2.69GHz. The realization of the layout and various issues related to the PA design is discussed and attempted to be solved.
Chiral Phosphoric Acid-Catalyzed Enantioselective Three-Component Povarov Reaction Using Enecarbamates as Dienophiles: Highly Diastereo- and Enantioselective Synthesis of Substituted 4-Aminotetrahydroquinolines (2011)

A chiral phosphoric acid (5)-catalyzed three-component Povarov reaction of aldehydes 2, anilines 3, and enecarbamates 4 afforded cis-4-amino-2-aryl(alkyl)-1,2,3,4-tetrahydroquinolines 1 in high yields with excellent diastereoselectivities (>95%) and almost complete enantioselectivities (up to >99% ee). The reaction was applicable to a wide range of anilines bearing electron-donating (OMe) and electron-withdrawing groups (e.g., Cl, CF(3), NO(2)) and allowed, for the first time, aliphatic aldehydes to be employed in the enantioselective Povarov reaction. With β-substituted acyclic enecarbamates, 2,3,4-trisubstituted 1,2,3,4-tetrahydroquinolines with three contiguous stereogenic centers were produced in excellent diastereo- and enantioselectivities (87 to >99% ee). A detailed study of the active catalytic species allowed us to reduce the catalyst loading from 10% to 0.5% with no deterioration of enantiomeric excess. In addition, mechanistic studies allowed us to conclude unequivocally that the Povarov reaction involving enecarbamate as dienophile proceeded via a stepwise mechanism. The key role of the free NH function of the enecarbamate in the success of this transformation was demonstrated. NMR experiments indicating the catalyst-substrate interaction as well as a linear correlation between catalyst and product ee's were also documented.