gebhart/patrepeval huggingface dataset:
The Effects of Ovine Prolactin on Water and Electrolyte Excretion in Man Are Attributable to Vasopressin Contamination (1977)

Prolactin is an important osmoregulatory hormone in several lower vertebrate species. The present study was undertaken to clarify the effects of prolactin, if any, on human renal function. Eight normal adult male subjects on a 150 mEq sodium (Na), 60 mEq potassium (K) diet for 5 days were studied during 12 h of oral water (H2O) loading on 2 consecutive days. On day 1, after a 6 h control period, a 1 ml normal saline placebo was given im; on day 2, 25 mg of ovine prolactin (OP) was substituted. The subjects were supine and received a constant infusion of Na and K. After OP, serum prolactin rose from 6.9+/-0.8 ng/ml to 15.0+/-2.5 ng/ml (P less than .01) at 1 h, 27.6+/-4.0 ng/ml (P less than .002) at 2 h, 33.1+/-4.3 ng/ml (P less than .001) at 3 h and remained elevated for the remaining 3 h of study. The ovine prolactin had 20-25% of the potency of human prolactin in the human prolactin radioimmunoassay system. In response to OP, free H2O clearance (CH2O) promptly decreased from 10.1 +/- .06 ml/min to 6.1 +/- .05 ml/min (P less than 0.1) at 1 h, to a nadir of 5.1+/-.3 ml/min (P less than .001) at 2 h, and returned to control levels by 4 h. CH2O was unchanged after placebo, and urinary Na and K excretion, creatinine and osmolar clearance (COSM), plasma Na, K, osmolality and aldosterone were unchanged after OP or placebo. Control plasma vasopressin was 1.0+/-0.1 micronU/ml and was not changed after prolactin (1.1+/-0.1 micronU/ml at 1 h, 1.1+/-0.1 micronU/ml at 2 h and 1.1+/-0.1 micronU/ml at 3 h). The ovine prolactin contained 2 micronU of immunoassayable vasopressin per microng of powder. Aqueous vasopressin, 50 mU (containing in 25 mg of ovine prolactin), produced a decrease in CH2O not significantly different from prolactin in 6 water loaded subjects. Four different subjects given 100 mg of OP had decreased CH2O from 8.3+/-0.3 to 2.7+/-0.7 ml/min at 1 h (P less than .001) and to 2.8+/-0.7 ml/min at 2 h (P less than .01). Control plasma osmolality was 301+/-4 mOsm/1 and decreased to a maximum of 288+/-5 mOsm/1 4 h after OP (P less than .001). After prolactin administration, plasma vasopressin rose from 0.44+/-0.15 to 0.80+/-0.41 micronU/ml (P =NS) at 1 h. The transient antidiuresis in response to ovine prolactin is due to contamination of the preparation with vasopressin. Prolactin does not acutely influence renal electrolyte excretion and probably does not influence water excretion in man.
Estrogen- and Progesterone-Dependent Secretory Changes in the Uterus of the Sheep1 (1992)

This study was undertaken to determine the effects of 17 beta-estradiol (E) and progesterone (P) on polypeptide synthesis and release from the uterus of the sheep. Uterine flushings (UF) and endometrium were obtained from ovariectomized untreated animals, ovariectomized animals treated with E (approximately 5-10 pg/ml) for 6 days (6E) and ovariectomized animals primed with E for 6 days then treated with P (approximately 1.5-3 ng/ml), in the continued presence of E, for an additional 6 days (6EP). Endometrium was cultured (24 h) in the presence of 3H-leucine (3H-leu) or 3H-glucosamine (3H-glcN), and newly synthesized and released proteins were detected in culture media by fluorography of 10% SDS gels. The quantity of proteins in UF and radiolabeled proteins in explant culture media did not change between treatment groups (p < 0.05). Qualitative changes in the synthesis and release of proteins were observed depending on the steroid treatment. An M(r) 57,000 protein was present in UF and 3H-leu-labeled culture media obtained from animals treated only with E and an M(r) > 200,000 was present in 3H-leu-labeled culture media of endometrium obtained from 6E and 6EP animals. An M(r) 44,000 protein was present only in UF from 6EP animals but could not be detected in endometrial culture media from animals undergoing this steroid treatment. These data show that the endometrium of the ovariectomized sheep undergoes alterations in secretory protein patterns which depend on the presence of E and P.
Use of Spectral Biometrics for Aliveness Detection (2011)

Numerous technologies are available for automatic verification of a person's identity. The authentication process usually involves verification of what a person knows (e.g., passwords, pass phrases, PINs), has (e.g., tokens, smart cards), is (e.g., fingerprint, hand geometry, facial features, retinal print, iris pattern), or generates (e.g., signature, voice). Use of something known by a person and use of something held by a person are two simple identification/verification solutions widely used today. Biometrics (also known as biometry) is defined as "the identification of an individual based on biological traits, such as fingerprints, iris patterns, and facial features" Using something one knows requires only a good memory, but can on the other hand be easily overheard, seen, or even guessed. An item that one holds can be stolen and used or copied later. Using biometrics might at first seem to overcome these problems since fingerprints, iris patterns, etc. are part of one's body and thus not easily misplaced, stolen, forged, or shared. Indeed, biometrics technology is becoming a preferred standard for identification and authentication in ATMs, credit card transactions, electronic transactions, e-passports, airports, international borders, nuclear facilities and other highly restricted areas. Presently Europe leads the way but, the highest growth potential is forecasted to be in Asia as many Asian countries have already started adopting the technology. Its market size is estimated to be US$7.1 billion by 2012 Ironically however, this widespread acceptance of biometrics technology has been attracting the attention of attackers and has provoked interest in exploration of spoofing mechanisms against biometric systems. For example, the thousands of fingerprints that one leaves everywhere in one's daily life can be recovered and molded into artificial fingers for fooling biometrics devices based on fingerprint detection. In an experiment conducted by Matsumoto et al., eleven optical and silicon fingerprint sensors accepted artificial fingers in at least sixty percent of attempts Furthermore, with a commercially available high resolution digital camera, the iris pattern of a person's eye can be readily extracted from the person's facial picture and molded into contact lenses to be used to fool machines employing iris pattern recognition. An experiment conducted on two commercial iris recognition devices also showed that one of these devices could be fooled 50% of the time and the other 100% of the time Although susceptibility of most biometric system to spoofing have been experimented on fingerprint and iris recognition devices as these technologies are used in a variety of www.intechopen.com
An Influence Gauge to Detect and Explain Relations between Measurements and a Performance Indicator (2015)

&#x0D; &#x0D; &#x0D; What about a software tool that behaves like a gauge able to estimate the quantity of information contained in a group of measurements? Then if we have a performance indicator or a defect rate, how may we compute the maximum performance explanation contained in our dataset? The first question may be answered by entropy and the second with mutual information. The present paper recalls a simple way to use those mathematical tools in an application one wants to launch each time a new dataset has to be studied. Often the PHM team in Snecma is asked to participate in special workforces to analyze sudden crisis. This methodology helps at the very beginning of the process to identify our mathematical capability to build an explanation model. This was the case during a small engine start crisis when some spark plugs were not working. Another time we used this tool to identify the flying condition when a gearbox was heating. This methodology was first developed for industry purposes like the optimization of machine tools or process recipes. Its success is in the simplifications of the computations that enlighten the interpretability of the results. Each signal is quantified in a way that improves the mutual information with the performance indicator. This is done signal by signal, but also for any small subsets of multivariate measurements until the confidence given by the quantity and quality of the data reaches its maximum. The segmentation of the data helps and boosts the computation of the integrals. Moreover, as this methodology uses quantified data as inputs it works as well with any sort of inputs such as continuous, discrete ordered and even categorized measurements. Once a best subset of measurements is selected a simple non-linear model is built using a relaxation algorithm. This model is a set of hypercubes that classifies the input space in a very simple and interpretable way. The methodology given below is a rough approach and may be replaced by more efficient regression algorithms if one only have continuous measurements but it has some advantages like a way to search a “best rule” according to some constraints and a graphic navigation tool very efficient to correct recipes.&#x0D; &#x0D; &#x0D;
Safety and Efficacy of Single Intra-Articular Injection of a Cross-Linked Hyaluronic Acid/Mannitol Formulation [Happycross®] in knee Osteoarthritis Results of a Prospective Observational Study in Daily Practice Conditions (2017)

journal of orthopaedics is an international, peer reviewed scientific journal focused towards publishing a complete and reliable source of information on the innovations and ongoing developments in the field of Orthopedics which includes extensive study in the fields of Hand surgery.
Modèle LSTM encodeur-prédicteur pour la prévision court-terme de l'affluence dans les transports collectifs (2019)

CAP 2019, Conférence sur l&apos;Apprentissage Automatique, Toulouse, France, 03-/07/2019 - 05/07/2019
Quantitative Analysis of Commercial Bisphenol A by Paper Chromatography (1959)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTQuantitative Analysis of Commercial Bisphenol A by Paper ChromatographyW. M. Anderson, G. B. Carter, and A. J. LanduaCite this: Anal. Chem. 1959, 31, 7, 1214–1217Publication Date (Print):July 1, 1959Publication History Published online1 May 2002Published inissue 1 July 1959https://pubs.acs.org/doi/10.1021/ac60151a043https://doi.org/10.1021/ac60151a043research-articleACS PublicationsRequest reuse permissionsArticle Views113Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The effects of alpha tocopherol supplementation on monocyte function. Decreased lipid oxidation, interleukin 1 beta secretion, and monocyte adhesion to endothelium. (1996)

Low levels of alpha tocopherol are related to a higher incidence of cardiovascular disease and increased intake appears to afford protection against cardiovascular disease. In addition to decreasing LDL oxidation, alpha tocopherol may exert intracellular effects on cells crucial in atherogenesis, such as monocytes. Hence, the aim of this study was to test the effect of alpha tocopherol supplementation on monocyte function relevant to atherogenesis. Monocyte function was assessed in 21 healthy subjects at baseline, after 8 wk of supplementation with d-alpha tocopherol (1,200 IU/d) and after a 6-wk washout phase. The release of reactive oxygen species (superoxide anion, hydrogen peroxide), lipid oxidation, release of the potentially atherogenic cytokine, interleukin 1 beta, and monocyte-endothelial adhesion were studied in the resting state and after activation of the monocytes with lipopolysaccharide at 0, 8, and 14 wk. There was a 2.5-fold increase in plasma lipid-standardized and monocyte alpha tocopherol levels in the supplemented phase. After alpha tocopherol supplementation, there were significant decreases in release of reactive oxygen species, lipid oxidation, IL-1 beta secretion, and monocyte-endothelial cell adhesion, both in resting and activated cells compared with baseline and washout phases. Studies with the protein kinase C inhibitor, Calphostin C, suggest that the inhibition of reactive oxygen species release and lipid oxidation is due to an inhibition of protein kinase C activity by alpha tocopherol. Thus, this study provides novel evidence for an intracellular effect of alpha tocopherol in monocytes that is antiatherogenic.
Minimally Invasive Approaches for Surgical Management of Primary Liver Cancers (2017)

The benefits of minimally invasive approaches in oncologic surgery are increasingly recognized, and laparoscopic liver surgery has become increasingly widespread. In light of the complexity and technical challenges of hepatobiliary procedures, robotic approaches are also employed. The utility, safety, and oncologic integrity of these methods in the management of primary liver cancers are reported. PubMed was used to search the medical literature for studies and articles pertaining to laparoscopic and robotic liver surgery. Studies that particularly addressed hepatocellular carcinoma and cholangiocarcinoma were identified and reviewed. Laparoscopic liver surgery, including for major resections, has been shown to be safe in experienced hands without any compromise of oncologic outcomes for either hepatocellular carcinoma or intrahepatic cholangiocarcinoma. Some studies show improved clinical outcomes including shorter hospital stays and lower complication rates when compared to open surgery, particularly for patients with cirrhosis. Robotic liver surgeries seem to have equally acceptable clinical outcomes; however, there is limited data regarding oncologic integrity and considerable additional expense. Laparoscopic and robotic liver resections are both feasible and safe for the management of primary liver tumors. Future studies should aim to clarify specific indications and optimize applications of these approaches.
Megadose 90Y-ibritumomab tiuxetan prior to allogeneic transplantation is effective for aggressive large B-cell lymphoma (2021)

Allogeneic hematopoietic cell transplantation (allo-HCT) can be curative for relapsed or refractory B-cell lymphomas (BCLs), although outcomes are worse in aggressive disease, and most patients will still experience relapse. Radioimmunotherapy using 90Y-ibritumomab tiuxetan can induce disease control across lymphoma subtypes in a dose-dependent fashion. We hypothesized that megadoses of 90Y-ibritumomab tiuxetan with reduced-intensity conditioning could safely produce deeper remissions in aggressive BCL further maintained with the immunologic effect of allo-HCT. In this phase 2 study, CD20+ BCL patients received outpatient 90Y-ibritumomab tiuxetan (1.5 mCi/kg; maximum, 120 mCi), fludarabine, and then 2 Gy total body irradiation before HLA-matched allo-HCT. Twenty patients were enrolled after a median of 4.5 prior lines of therapy, including 14 with prior autologous transplant and 4 with prior anti-CD19 chimeric T-cellular therapy. A median 90Y-ibritumomab tiuxetan activity of 113.6 mCi (range, 71.2-129.2 mCi) was administered, delivering a median of 552 cGy to the liver (range, 499-2411 cGy). The estimated 1- and 5-year progression-free survival was 55% (95% confidence interval [CI], 31-73) and 50% (95% CI, 27-69) with a median progression-free survival of 1.57 years. The estimated 1- and 5-year overall survival was 80% (95% CI, 54-92) and 63% (95% CI, 38-81) with a median overall survival of 6.45 years. Sixteen patients (80%) experienced grade 3 or higher toxicities, although nonrelapse mortality was 10% at 1 year. No patients developed secondary acute myeloid leukemia/myelodysplastic syndrome. Megadose 90Y-ibritumomab tiuxetan, fludarabine, and low-dose total body irradiation followed by an HLA-matched allo-HCT was feasible, safe, and effective in treating aggressive BCL, exceeding the prespecified end point while producing nonhematologic toxicities comparable to those of standard reduced-intensity conditioning regimens.
Production of Ac-225 from Th-229 for Targeted α Therapy (2005)

This work describes a method for the separation and purification of Ac-225 from a Th-229 source. The procedure is based on the combination of ion exchange and extraction chromatographic methods in nitric acid media and allows the preparation of carrier-free, clinical grade Ac-225 with an overall yield exceeding 95%. Quality control of the product is performed using radiometric (alpha, gamma spectrometry) and mass spectrometric methods. The Ac-225 product can be loaded on a radionuclide generator for the preparation of Bi-213 for preclinical and clinical studies of targeted alpha therapy of cancer and infectious diseases.
Combination of Electrografting and Ring-Opening Metathesis Polymerization: An Efficient Way to Prepare Polynorbornene Brushes on Conducting Substrates The authors thank the "Services Fédéraux des Affaires Scientifiques, Techniques et Culturelles" for general support under the auspices of the "Poles d'Attraction Interuniversitaires: Supramolecular Catalysis and Supramolecular Chemistry". C.J. is "Chargé de Recherche" at the "Fonds National pour la Recherche Scientifique" (FNRS). (2001)

Controlling the adhesion: a poly(norbornenylmethylene acrylate) coating was electrografted onto various conducting substrates, in a subsequent step, an initiator of ring-opening metathesis polymerization (ROMP) was attached to the norbornene pendant groups, and norbornene was polymerized, so forming a strongly adhering coating (see picture). This strategy which combines the “electrografting from” method and the more classical “grafting from” copolymerization is a novel powerful way to control adhesion, thickness, and the chemical properties of organic coatings.
A computer-aided change detection system for paediatric acute intracranial haemorrhage (2008)

In this paper, we apply computer science and software engineering techniques in, and bring benefits to, real-life applications. Specifically, we propose a design for a computeraided change detection system, which uses both image processing and data mining techniques, to help clinicians diagnose bleeding in children's brains---i.e., in medical terms, paediatric acute intracranial haemorrhage (AIH). The proposed system provides clinicians with computerized analysis of medical images in the form of computed tomography (CT) scans of the heads of children patients. This, in turn, leads to more efficient detection, diagnosis, and progress evaluation of paediatric AIH.
Plane wave elastography: a frequency-domain ultrasound shear wave elastography approach (2021)

In this paper, we propose plane wave elastography (PWE), a novel ultrasound shear wave elastography (SWE) approach. Currently, commercial methods for SWE rely on directional filtering based on the prior knowledge of the wave propagation direction, to remove complicated wave patterns formed due to reflection and refraction. The result is a set of decomposed directional waves that are separately analyzed to construct shear modulus fields that are then combined through compounding. Instead, PWE relies on a rigorous representation of the wave propagation using the frequency-domain scalar wave equation to automatically select appropriate propagation directions and simultaneously reconstruct shear modulus fields. Specifically, assuming a homogeneous, isotropic, incompressible, linear-elastic medium, we represent the solution of the wave equation using a linear combination of plane waves propagating in arbitrary directions. Given this closed-form solution, we formulate the SWE problem as a nonlinear least-squares optimization problem which can be solved very efficiently. Through numerous phantom studies, we show that PWE can handle complicated waveforms without prior filtering and is competitive with state-of-the-art that requires prior filtering based on the knowledge of propagation directions.
Effect of Nucleotide and Nucleoside Mixture on Rats Given Total Parenteral Nutrition after 70% Hepatectomy (1985)

After partial hepatectomy rats were used as a model of patients with liver tumor after extensive hepatectomy. Supplementation of a nucleotide and nucleoside mixture to the total parenteral nutrition solution in rats after 70% hepatectomy resulted in earlier restoration of the nitrogen balance in the first 3 days than the solution without this supplementation. This supplementation had no unfavorable effects on the compositions of the blood and urine, and particularly the metabolites of nucleic acids such as uric acid, beta-alanine, and beta-aminoisobutyric acid. A suitable ratio of nucleotides plus nucleoside to amino acids was tentatively concluded to be 1:2 g N with a calorie supply of 400 kcal.
Developing Structural Equation Models To Determine Factors Contributing to Student Graduation and Retention: Are There Differences for Native Students and Transfers?. (2002)

Studies have provided conflicting findings on who is more likely to graduate or to persist in higher education. This study examined differences between native students and transfer students in terms of graduation and retention rates, sought to discover factors that impact students' persistence in higher education, such as a student's first-term grade point average (GPA), overall average GPA, age, gender, race, and residency (in-state versus out-of-state). The study aimed to develop a systematic and comprehensive model to determine the extent to which these factors interact and influence graduation and retention rates. All undergraduate degree-seeking students enrolled at an institution for the first time in fall 1994 were selected for the study. Of this group, 2,545 were first-time freshmen, and 1,194 were transfers. Findings agree with those from other studies that first-term academic performance is crucial for both native and transfer students in terms of their graduation and persistence. It also indicates that transfer credit hours do make a difference in graduation and retention rates. Transfer students who transferred less than 32 credit hours are less likely to graduate than native students, while transfer students with 32 or more credit hours transferred graduate at a significantly higher rate within 4 years than do native students. Structural equation models also indicate that transfer credit hours have a strong effect on transfer student graduation and retention rates. In agreement with other studies, this study finds that student ethnicity, sex, and age had no effect on student graduation or retention rates, but student academic performance did. (Contains 6 tables, 4 figures, and 17 references.) (SLD) Reproductions supplied by EDRS are the best that can be made from the original document. cr) 00 00 Developing Structural Equation Models to Determine Factors Contributing to Student Graduation and Retention: Are There Differences for Native Students and Transfers?