gebhart/patrepeval huggingface dataset:
Network slice selection, assignment and routing within 5G Networks (2016)

5G Networks are anticipated to provide a diverse set of services over Network Slices (NS) using Network Function Virtualization (NFV) technologies. We propose solutions to enable NS selection and routing of traffic routing through a NS. A framework for enabling negotiation, selection and assignment of NSs for requesting applications in 5G networks is presented. A definition for service description has been developed, which is then leveraged for negotiation between an application/user equipment and the serving network. Virtualized networks or slices of virtualized networks are selected and assigned based on QCI and security requirements associated with a requested service. We also describe static and dynamic mechanisms for packet routing within NSs.
Functionalization of carbon nanotubes by water plasma (2012)

Multiwall carbon nanotubes grown by plasma enhanced chemical vapour deposition were functionalized by H(2)O plasma treatment. Through a controlled functionalization process of the carbon nanotubes (CNTs) we were able to modify and tune their chemical reactivity, expanding the range of potential applications in the field of energy and environment. In particular, different oxygen groups were attached to the surfaces of the nanotubes (e.g. carboxyl, hydroxyl and carbonyl), which changed their physicochemical properties. In order to optimize the main operational parameters of the H(2)O plasma treatment, pressure and power, a Box-Wilson experimental design was adopted. Analysis of the morphology, electrochemical properties and functional groups attached to the surfaces of the CNTs allowed us to determine which treatment conditions were suitable for different applications. After water plasma treatment the specific capacitance of the nanotubes increased from 23 up to 68 F g(-1) at a scan rate of 10 mV s(-1).
Graphene for detection and creation of terahertz light (2019)

Resumen del trabajo presentado a la NanoSpain Conference, celebrada en Barcelona (España) del 28 al 31 de mayo de 2019.
First excitedA=9isospin quartet (1974)

The first excited state of $^{9}\mathrm{C}$ and its analog in $^{9}\mathrm{B}$ have been observed, and their mass excesses and widths have been measured. This completes a new mass quartet which differs from the predictions of the isobaric multiple mass equation less significantly than the ground state $A=9$ quartet.NUCLEAR REACTIONS $^{12}\mathrm{C}$ ($^{3}\mathrm{He}$, $^{6}\mathrm{He}$), $E=74$ MeV measured ${E}_{x}$ of $^{9}\mathrm{C}$ first excited state. $^{11}\mathrm{B}(p,t)$, $E=46.5$ MeV, measured ${E}_{x}$ of second $T=\frac{3}{2}$ level in $^{9}\mathrm{B}$. Decuced coefficient of multiplet mass equation for first excited $A=9$ quartet.
Reconstruction of the Lagrangian deformation of the aorta from 4D MRI data (2021)

This paper presents a novel approach to track objects from 4D Flow MRI data. A salient feature of the proposed method is that it fully exploits the geometrical and dynamical nature of the information provided by this imaging modality. The underlying idea consists in formulating the tracking problem as a data assimilation problem, in which both position and velocity observations are extracted from the 4D Flow MRI data series. Optimal estate estimation is then performed in a sequential fashion via Kalman filtering. The capabilities of the method are extensively assessed in a numerical study involving synthetic and clinical data.
Lock-in pixels readout circuit using a high speed lateral electric field modulator with differential charge accumulation for stimulated Raman scattering imager (2014)

In this paper, a lock-in pixel readout circuits using a high speed lateral electric field modulator with differential charge accumulation for a stimulated Raman scattering imager is presented. The stimulated Raman scattering works by detecting the vibrations in chemical bonds between atoms, and the generated Raman signal after stimulated scattering processes is very low compared to offset signal. By using a high-speed lateral electric field modulator with lock-in pixels differential charge accumulation technique using a sample-and hold circuit with a fully differential amplifier, very small effective Raman signal can be extracted from large offset signal and high dynamic range is achieved.
Effect of marital status on patient-reported outcomes following total hip arthroplasty: a matched analysis with minimum 2-year follow-up (2019)

Our study demonstrated inferior absolute PRO scores at latest follow-up for patients who were non-married compared to married following THA. These results show that while total hip replacement may still yield clinical benefit in all patients, non-married patients may ultimately achieve an inferior functional status, and expectations should be adjusted accordingly. Physicians should assess levels of psychosocial support in their patients prior to undergoing hip arthroplasty in order to optimise results.
Riding the Rangelands Piggyback: A Resilience Approach to Conservation Management (2009)

This chapter contains sections titled: Introduction Resilience Multiple interacting thresholds Identifying thresholds System identity and the significance of a regime shift Dealing with resilience Some insights from a comparison of regional case studies References
Asymetry of critical exponents in YBCO in the overdoped, optimally doped and underdoped regime. (1998)

International audience
Adversarial EXEmples (2021)

Recent work has shown that adversarial Windows malware samples—referred to as adversarial EXE mples in this article—can bypass machine learning-based detection relying on static code analysis by perturbing relatively few input bytes. To preserve malicious functionality, previous attacks either add bytes to existing non-functional areas of the file, potentially limiting their effectiveness, or require running computationally demanding validation steps to discard malware variants that do not correctly execute in sandbox environments. In this work, we overcome these limitations by developing a unifying framework that does not only encompass and generalize previous attacks against machine-learning models, but also includes three novel attacks based on practical, functionality-preserving manipulations to the Windows Portable Executable file format. These attacks, named Full DOS , Extend , and Shift , inject the adversarial payload by respectively manipulating the DOS header, extending it, and shifting the content of the first section. Our experimental results show that these attacks outperform existing ones in both white-box and black-box scenarios, achieving a better tradeoff in terms of evasion rate and size of the injected payload, while also enabling evasion of models that have been shown to be robust to previous attacks. To facilitate reproducibility of our findings, we open source our framework and all the corresponding attack implementations as part of the secml-malware Python library. We conclude this work by discussing the limitations of current machine learning-based malware detectors, along with potential mitigation strategies based on embedding domain knowledge coming from subject-matter experts directly into the learning process.
Gluco-Metabolic Effects of Pharmacotherapy-Induced Modulation of Bile Acid Physiology (2019)

Any potential beneficial gluco-metabolic effects of FXR agonists remain to be established, whereas the clinical relevance of TGR5-based treatment modalities seems limited because of substantial safety concerns of TGR5 agonists observed in animal models. The glucose-lowering effects of ASBT inhibitors, bile acid sequestrants, and metformin are at least partly mediated by modulation of bile acid circulation, which might allow an optimization of these bile acid-modulating treatment modalities. (J Clin Endocrinol Metab XX: 00-00, 2019).
Galectin-9 gene (LGALS9) polymorphisms are associated with rheumatoid arthritis in Brazilian patients (2019)

The rs4239242 TT genotype showed a positive association with RA (p = 0.0032, odds ratio = 0.28), and heterozygous TC were prevalent in the control group compared to RA patients (p = 0.0001, odds ratio = 7.99). Galectin-9 serum levels were significantly increased in RA patients compared to the control group (p<0.0001). Patients in remission had high levels of galectin compared to the moderate activity group (p<0.0001). Regarding the Clinical Disease Activity Index (CDAI), patients in remission or low activity presented high levels of galectin when compared to patients in severity (p<0.0001). Patients performing moderate activity had a significant value compared to patients who were in high disease severity (p = 0.0064). Interestingly, the AG genotype (rs3763959) has been associated with a higher presence of bone erosion in RA patients (p = 0.0436). The SNP rs4239242 TT genotype showed a positive association with RA in comparison to the control group. The AG genotype (rs3763959) has been associated with a higher presence of bone erosion in RA patients.
Dipyrrinphenol–Mn(iii) complex: synthesis, electrochemistry, spectroscopic characterisation and reactivity (2011)

Herein, we report the manganese complex with a novel trianionic ligand, the pentafluorophenyldipyrrinphenol ligand DPPH(3). The X-ray crystal structure reveals that the Mn(III) complex exists in a dimeric form in the solid state. Electrochemical studies indicate two quasi-reversible one electron oxidation processes. EPR data on the one electron oxidised species in solution support the formation of a monuclear Mn complex with an S = 3/2 spin system. Preliminary studies towards epoxidation reactions were tested in the presence of iodosylbenzene (PhIO) and are in favour of an oxygen-atom-transfer (OAT) reaction catalyzed by the Mn(III) complex.
[Long-term evolution of nodular lymphoma. Outcome in 85 patients treated between 1968 and 1975 (author's transl)]. (1981)

Eighty-five patients with nodular lymphoma diagnosed between 1968 and 1975 were followed up for long periods and were treated by either conventional methods (local radiotherapy and single drug chemotherapy) or by more intensive therapeutic regimens, such as initial combined M.O.P.P. therapy and maintenance treatment with chlorambucil with or without further courses of M.O.P.P. Long-term follow-ups have brought to light some interesting points concerning the prognosis. Dissemination of the disease and large-cell histological pattern were, as already known, unfavourable factors. Neither age nor sex, nor bone-marrow involvement seemed to have any influence. Obtaining complete remissions improved the prognosis, but intensifying the initial and maintenance treatments proved disappointing: the survival rate remained the same, and the incidence of drug induced leukaemias was high. Indeed, relapses appeared to be less responsive to treatment when the patient had initially received multiple chemotherapy. However, in view of the high death rate of the disease (one-third of the patients in this series died within the first 5 years), trying new therapeutic regimens in the hope of obtaining better results, as has been done in Hodgkin's disease, would be fully justified.
Response of MG63 osteoblast-like cells to ordered nanotopographies fabricated using colloidal self-assembly and glancing angle deposition (2015)

Ordered surface nanostructures have attracted much attention in different fields including biomedical engineering because of their potential to study the size effect on cellular response and modulation of cell fate. However, the ability to fabricate large-area ordered nanostructures is typically limited due to high costs and low speed of fabrication. Herein, highly ordered nanostructures with large surface areas (>1.5 × 1.5 cm(2)) were fabricated using a combination of facile techniques including colloidal self-assembly, colloidal lithography, and glancing angle deposition (GLAD). An ordered tantalum (Ta) pattern with 60-nm-height was generated using colloidal lithography. A monolayer of colloidal crystal, i.e., hexagonal close packed 720 nm polystyrene particles, was self-assembled and used as a mask. Ta patterns were subsequently generated by evaporation of Ta through the mask. The feature size was further increased by 100 or 200 nm using GLAD, resulting in the fabrication of four different surfaces (FLAT, Ta60, GLAD100, and GLAD200). Cell adhesion, proliferation, and mineralization of MG63 osteoblast-like cells were investigated on these ordered nanostructures over a 1 week period. Our results showed that cell adhesion, spreading, focal adhesion formation, and filopodia formation of the MG63 osteoblast-like cells were inhibited on the GLAD surfaces, especially the initial (24 h) attachment, resulting in a lower cell density on the GLAD surfaces. After 1 week culture, alkaline phosphatase activity and the amount of Ca was higher on the GLAD surfaces compared with Ta60 and FLAT controls, suggesting that the GLAD surfaces facilitate differentiation of osteoblasts. This study demonstrates that ordered Ta nanotopographies synthesized by combining colloidal lithography with GLAD can improve the mineralization of osteoblast-like cells providing a new platform for biomaterials and bone tissue engineering.
Cell and sarcomere contractile performance from the same cardiocyte using video microscopy (1993)

The relationship between whole cell and sarcomere contractile performance from within the same myocyte remains unclear. In the present study, the dynamic properties of whole cell and sarcomere contractile performance were examined from the same myocyte by computer-assisted video microscopy. Isolated canine left ventricular myocytes were field stimulated at 1 Hz, and whole cell and sarcomere contractile performance was measured in the unloaded unattached state (n = 16) and after attachment to a basement membrane substrate (n = 18). Whole cell and sarcomere contractile measurements were obtained immediately on initiation of electrical stimulation as well as at steady state, after which measurements were repeated in the presence of 25 nM isoproterenol. Video-microscopic images of whole cell and sarcomere contractions were obtained at final magnifications of x1,100 and x5,500, respectively. By use of a 240-Hz high-scan-rate charge-coupled device camera and a video-based edge-detection system synchronized with the camera video output, the myocyte and sarcomere motion data were digitized. Steady-state percentage and velocity of shortening for whole cells and sarcomeres were 4.75 +/- 0.30% and 56.50 +/- 2.37 microns/s and 8.63 +/- 0.60% and 2.24 +/- 0.46 microns/s, respectively, for the attached myocytes and 8.63 +/- 0.48% and 71.38 +/- 6.14 microns/s and 11.73 +/- 3.22% and 2.72 +/- 0.62 microns/s, respectively, for the unattached myocytes. With the initiation of electrical stimulation, the extent of the shortening-velocity of relengthening relationship increased in a linear fashion for the attached (whole cell, r = 0.87; sarcomere, r = 0.90; both P < 0.001) and unattached myocytes (whole cell, r = 0.83; sarcomere, r = 0.88; both P < 0.001). In all experiments, isoproterenol significantly increased the slope of these linear relationships (P < 0.01). Furthermore, the relationship between whole cell and sarcomere velocity of shortening was highly linear (r > 0.91, P < 0.001). In summary, this study demonstrated that the video-based edge-detection technique could be adapted to measure cell and sarcomere contractile performance from the same myocyte. Furthermore, a significant linear relationship exists between whole cell and sarcomere contractile dynamics with alterations in both load and inotropic state.
Spatially-adaptive temporal smoothing for reconstruction of dynamic and gated image sequences (2002)

In this paper we propose a method for spatio-temporal reconstruction of dynamic or gated image sequences. In a method we proposed previously, temporal smoothing in a Karhunen-Loeve (KL) transform domain was used prior to reconstruction to reduce the effect of noise. Unlike the Bayesian priors that are usually used in image reconstruction, temporal KL smoothing is a data-driven approach that takes advantage of the fact that the desired part of the data is characterized by strong inter-frame correlations, whereas the noise is uncorrelated. In this paper we improve on one of our group's previous techniques by making the temporal smoothing adapt spatially to local characteristics in the projection data. This improves the noise performance of the temporal smoothing, while significantly lessening the possibility of signal distortion. In the proposed method, spatial regions of the projection data sequence having similar time characteristics are identified by an unsupervised k-means clustering algorithm. A different KL transformation is designed for each spatial region in projection space, adapting the smoothing to the local temporal behavior. Finally, images are reconstructed from the smoothed projections by using the expectation-maximization (EM) algorithm. Experimental computer simulation results are shown that demonstrate potential improvements in image quality obtained by this technique for dynamic and gated imaging applications in brain, lesion, and cardiac imaging.
Combining 2D feature tracking and volume reconstruction for online video-based human motion capture (2003)

The acquisition of human motion data is of major importance for creating interactive virtual environments, intelligent user interfaces, and realistic computer animations. Today's performance of off-the-shelf computer hardware enables marker-free non-intrusive optical tracking of the human body. In addition, recent research shows that it is possible to efficiently acquire and render volumetric scene representations in real-time. This paper describes a system to capture human motion at interactive frame rates without the use of markers or scene-intruding devices. Instead, 2D computer vision and 3D volumetric scene reconstruction algorithms are applied directly to the image data. A person is recorded by multiple synchronized cameras, and a multilayer hierarchical kinematic skeleton is fitted to each frame in a two-stage process. We present results with a prototype system running on two PCs.
An evaluation of temporal geochemical evolution of Loihi Summit Lavas: Results from Alvin submersible dives (1993)

Stratigraphically controlled sequences of in situ lavas were collected from Loihi Seamount using the Alvin submersible to evaluate the volcano's temporal geochemical evolution. Three sections with up to 370 m of relief were sampled from the two pit craters at the summit of Loihi. All of the analyses were done on glass separates. Our results indicate that tholeiitic and alkalic volcanism at the summit of Loihi has been coeval. The tholeiitic and alkalic lavas have similar incompatible element patterns and O, Pb, Sr, and Nd isotope ratios but are distinct in some incompatible element ratios. These results are consistent with the different Loihi rock types being derived by variable degrees of melting from a common source. The crossing and light‐rare‐earth‐enriched rare earth element patterns and variable Sc/Yb ratios of the tholeiites indicate that their source was a garnet lherzolite. The relatively low δ 18 O values (∼4.9 ‰) for Loihi lavas are interpreted to be characteristic of the Hawaiian plume.
Simultaneous Displacement/Force Self-Sensing in Piezoelectric Actuators and Applications to Robust Control. (2015)

International audience
Data from Therapeutic Targeting the Loss of the Birt-Hogg-Dubé Suppressor Gene (2023)

&lt;div&gt;Abstract&lt;p&gt;Brit-Hogg-Dubé (BHD) syndrome, an autosomal dominant familial cancer, is associated with increased risk of kidney cancer. BHD syndrome is caused by loss-of-function mutations in the folliculin (FLCN) protein. To develop therapeutic approaches for renal cell carcinoma (RCC) in BHD syndrome, we adopted a strategy to identify tumor-selective growth inhibition in a RCC cell line with &lt;i&gt;FLCN&lt;/i&gt; inactivation. The COMPARE algorithm was used to identify candidate anticancer drugs tested against the NCI-60 cell lines that showed preferential toxicity to low &lt;i&gt;FLCN&lt;/i&gt; expressing cell lines. Fifteen compounds were selected and detailed growth inhibition (SRB) assays were done in paired BHD RCC cell lines (UOK257 derived from a patient with BHD). Selective sensitivity of FLCN-null over FLCN-wt UOK257 cells was observed in seven compounds. The most selective growth-inhibitory sensitivity was induced by mithramycin, which showed an approximately 10-fold difference in GI&lt;sub&gt;50&lt;/sub&gt; values between FLCN-null (64.2 ± 7.9 nmol/L, &lt;i&gt;n&lt;/i&gt; = 3) and FLCN-wt UOK257 cells (634.3 ± 147.9 nmol/L, &lt;i&gt;n&lt;/i&gt; = 4). Differential ability to induce caspase 3/7 activity by mithramycin was also detected in a dose-dependent manner. Clonogenic survival studies showed mithramycin to be approximately 10-fold more cytotoxic to FLCN-null than FLCN-wt UOK257 cells (200 nmol/L). Following mithramycin exposure, UOK257-FLCN-null cells were mainly arrested and blocked in S and G&lt;sub&gt;2&lt;/sub&gt;-M phases of the cell cycle and low dose of rapamycin (1 nmol/L) potentiated mithramycin sensitivity (1.5-fold in G&lt;sub&gt;2&lt;/sub&gt;-M population and 2-fold in G&lt;sub&gt;2&lt;/sub&gt;-M period time, 2xGI&lt;sub&gt;50&lt;/sub&gt;, 48 hours). These results provide a basis for further evaluation of mithramycin as a potential therapeutic drug for RCC associated with BHD. &lt;i&gt;Mol Cancer Ther; 10(1); 80–9. ©2011 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;
Stressed liquid crystals and their application (2005)

Recently discovered stressed liquid crystals (SLCs) are of a great interest because they provide largest phase retardation shift achievable within shortest time interval. This effect was accomplished by decoupling the speed of a liquid crystal layer from its thickness. SLCs easily switch 5 microns of the phase retardation at sub-millisecond speeds while 50 microns requires only several milliseconds. SLCs are therefore able to modulate the IR light with the frequencies higher than 10 kHz. The SLCs are polymer/liquid crystal composites; however, their electro-optic properties differ significantly from previously developed polymer dispersed liquid crystals and polymer network/stabilized liquid crystals. The applied stressed force aligns the domains, eliminating scattering and hysteresis at the same time. The phase shift is highly linear with the applied voltage, greatly simplifying the drive electronics. The SLCs pose intriguing basic scientific questions and may be used in a lot of new electro-optical applications (micro-displays, diffractive optical elements, beam steering devices).
An open architecture for tool and process integration (2002)

The SoftBench Framework is a set of software services that allows tools and processes to be tied together into an integrated, distributed environment. The Framework allows tools that were created as stand-alone applications to be encapsulated, or plugged-in, without source code modification. These encapsulated tools can then communicate with each other to become a part of a user's task or overall process. The SoftBench Framework allows tasks to be created by the user, quickly and easily. As each user's needs change, the tasks can evolve to meet these needs. This work describes the technical aspects and architecture of the SoftBench Framework, and how these services allow customers to create integrated software environments.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>