gebhart/patrepeval huggingface dataset:
Hypersecretion of an Abnormal Form of Follicle-Stimulating Hormone Associated with Suppressed Luteinizing Hormone Secretion in a Woman with a Pituitary Adenoma* (1981)

Pituitary tumors producing FSH have hitherto been reported only in males, all of whom have had normal or raised LH levels in serum. This report describes a female with a pituitary adenoma associated with supranormal serum levels of FSH. The FSH was also qualitatively abnormal when compared with FSH in the serum of other postmenopausal women, had a lower apparent molecular weight on gel chromatography, and was less negatively charged, as shown by electrophoresis. The results of LRH tests and suppression tests with ethinyl estradiol indicated autonomy of the FSH-producing adenoma. The FSH level increased concomitant with tumor enlargement and decreased after surgical removal of the pituitary adenoma or pituitary irradiation. The serum level of the glycoprotein alpha-subunit was raised about 100-fold. Any free FSH beta-subunits were not detectable in serum. The abnormal FSH had antigenic sites in common with both the alpha- and beta-subunits of FSH. The LH level was extremely low, and there was no response to LRH tests or ethinyl estradiol treatment. After gel chromatography, a small amount of LH, corresponding to 1/50th of the average for the patient's age, was detected at the position for normal LH. There was no GH response to insulin-induced hypoglycemia, while the cortisol increase was normal. Thyroid and adrenal functions were normal. The PRL level was within the normal range and increased slightly after estrogen treatment.
Review: Transurethral Microwave Thermotherapy in Benign Prostatic Hyperplasia (1993)

The transurethral microwave thermotherapy (TUMT) method combines the principles of microwave radiative heating and conductive cooling to destroy tissue within the prostate while preserving the other structures of the lower urinary tract. The method is effective in benign prostatic hyperplasia (BPH), as demonstrated by laboratory and clinical studies. The ease of the 1-hour office treatment, the dramatic symptomatic improvement and reasonable uroflow rates that result, the preservation of sexual function, the apparent safety, and the durability of the result may mean that TUMT will introduce changes in the management of BPH as dramatic as those brought about in lithiasis management by ESWL.
A distance routing effect algorithm for mobility (DREAM) (1998)

Article Free Access Share on A distance routing effect algorithm for mobility (DREAM) Authors: Stefano Basagni Erik Jonsson School of Engineering and Computer Science, The University of Texas at Dallas Erik Jonsson School of Engineering and Computer Science, The University of Texas at DallasView Profile , Imrich Chlamtac Erik Jonsson School of Engineering and Computer Science, The University of Texas at Dallas Erik Jonsson School of Engineering and Computer Science, The University of Texas at DallasView Profile , Violet R. Syrotiuk Erik Jonsson School of Engineering and Computer Science, The University of Texas at Dallas Erik Jonsson School of Engineering and Computer Science, The University of Texas at DallasView Profile , Barry A. Woodward Erik Jonsson School of Engineering and Computer Science, The University of Texas at Dallas Erik Jonsson School of Engineering and Computer Science, The University of Texas at DallasView Profile Authors Info & Claims MobiCom '98: Proceedings of the 4th annual ACM/IEEE international conference on Mobile computing and networkingOctober 1998 Pages 76–84https://doi.org/10.1145/288235.288254Published:25 October 1998Publication History 704citation5,003DownloadsMetricsTotal Citations704Total Downloads5,003Last 12 Months353Last 6 weeks41 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Electroabsorption in the type II superlattices (1992)

Electric field dependence of the optical absorption in the ZnSe0.35Te0.65-ZnSe type II superlattice has been studied. An extremely large blue shift of the absorption edge found for the structure makes it an attractive choice for the waveguide visible light modulators.
Multi-Watt Broadly-Tunable Diode-Pumped Cr:ZnSe Laser (2012)

We present record power of 3.7 W from a CW Cr:ZnSe laser pumped directly with a diode laser. Power &gt;1.5 W over the tuning range of 2200-2600 nm is presented. A first-of-kind demonstration of electro-optic tuning is also presented.
Quantum Dots-Converted Light-Emitting Diodes Packaging for Lighting and Display: Status and Perspectives (2016)

Recent years, semiconductor quantum dots (QDs) have attracted tremendous attentions for their unique characteristics for solid-state lighting (SSL) and thin-film display applications. The pure and tunable spectra of QDs make it possible to simultaneously achieve excellent color-rendering properties and high luminous efficiency (LE) when combining colloidal QDs with light-emitting diodes (LEDs). Due to its solution-based synthetic route, QDs are impractical for fabrication of LED. QDs have to be incorporated into polymer matrix, and the mixture is dispensed into the LED mold or placed onto the LED to fabricate the QD–LEDs, which is known as the packaging process. In this process, the compatibility of QDs' surface ligands with the polymer matrix should be ensured, otherwise the poor compatibility can lead to agglomeration or surface damage of QDs. Besides, combination of QDs–polymer with LED chip is a key step that converts part of blue light into other wavelengths (WLs) of light, so as to generate white light in the end. Since QD-LEDs consist of three or more kinds of QDs, the spectra distribution should be optimized to achieve a high color-rendering ability. This requires both theoretical spectra optimization and experimental validation. In addition, to prolong the reliability and lifetime of QD-LEDs, QDs have to be protected from oxygen and moisture penetration. And the heat generation inside the package should be well controlled because high temperature results in QDs' thermal quenching, consequently deteriorates QD-LEDs' performance greatly. Overall, QD-LEDs' packaging and applications present the above-mentioned technical challenges. A profound and comprehensive understanding of these problems enables the advancements of QD-LEDs' packaging processes and designs. In this review, we summarized the recent progress in the packaging of QD-LEDs. The wide applications of QD-LEDs in lighting and display were overviewed, followed by the challenges and the corresponding progresses for the QD-LEDs' packaging. This is a domain in which significant progress has been achieved in the last decade, and reporting on these advances will facilitate state-of-the-art QD-LEDs' packaging and application technologies.
Investigation of the active center and catalytic mechanism of porcine kidney aminoacylase: a model of the active center. (1980)

Procine kidney aminoacylase (E.C. 3.5.1.14) is inhibited neither by phenylmethylsulfonylfluoride nor by alkylating agents (iodoacetate or iodoacetamide). Therefore reaction mechanisms including the formation of acylenzyme through seryl or cysteinyl side chains are ruled out. The enzyme is a metalloprotein that can be inactivated by ECTA and in which Co2+ is an equivalent substitute for the Zn2+ ion. The two SH groups/subunit of aminoacylase exhibit different reactivites to p-hydroxymercuribenzoate. Modification of the less reactive SH group reversibly inactivates the enzyme. We suggest that this cysteinyl side chain is situated in the active center or in its immediate vicinity. On the basis of our results we suppose a close similarity between aminoacylase and carboxypeptidase A with respect to their active center and catalytic mechanism.
A Novel Halogenated Compound Possessing Antibiotic and Cytotoxic Activities Isolated from the Fungus Resinicium pinicola (J. Erikss.) Erikss. & Hjortst (1994)

Pinicoloform, a novel unbranched acyclic compound containing a trichloromethyl group, has been isolated from extracts of the mycelia of the Basidiomycete Resinicium pinicola. It was isolated because of its ability to induce morphological and physiological differentiation of mammalian cells, although it also exhibits antibiotic and cytotoxic activities. The structure of pinicoloform was determined by spectroscopic methods.
Supporting autonomic computing functionality via dynamic operating system kernel aspects (2005)

To master the complexity of software systems in the presence of unexpected events potentially affecting system operation, the Autonomic Computing Initiative [16] aims to build systems that have the ability to control and organize themselves to meet unforeseen changes in the hard- and software environment.The basic principles employed by autonomic computing are self-configuration, self-optimization, self-healing and self-protection. Typically, these principles are cross-cutting concerns, so an obvious approach to their realization in software is to use aspect-oriented programming (AOP). Since autonomic systems have to adapt their behavior to changing runtime conditions, a dynamic AOP approach is required to implement autonomic computing functionality.This paper introduces the TOSKANA toolkit for deploying dynamic aspects into an operating system kernel as a central part of a computer system having an overview of current system operation and resource usage. TOSKANA provides before, after and around advice for in-kernel functions and supports the specification of pointcuts as well as the implementation of aspects themselves as dynamically exchangeable kernel modules. The use of TOSKANA is demonstrated by several examples indicating the cross-cutting nature of providing autonomic computing functionality in an operating system kernel. Performance results are presented to characterize the aspect deployment overhead incurred by using TOSKANA.
Micro-optofluidic Lenses: A review (2010)

This review presents a systematic perspective on the development of micro-optofluidic lenses. The progress on the development of micro-optofluidic lenses are illustrated by example from recent literature. The advantage of micro-optofluidic lenses over solid lens systems is their tunability without the use of large actuators such as servo motors. Depending on the relative orientation of light path and the substrate surface, micro-optofluidic lenses can be categorized as in-plane or out-of-plane lenses. However, this review will focus on the tunability of the lenses and categorizes them according to the concept of tunability. Micro-optofluidic lenses can be either tuned by the liquid in use or by the shape of the lens. Micro-optofluidic lenses with tunable shape are categorized according to the actuation schemes. Typical parameters of micro-optofluidic lenses reported recently are compared and discussed. Finally, perspectives are given for future works in this field.
Thermal Shifts in the Energy Levels of LaF_3:Nd^3+* (1967)

We have measured the temperature dependence of the linewidths and positions for a number of transitions in the spectrum of LaF3:Nd3+. As the temperature increases, all lines broaden because of relaxation and Raman scattering of phonons. Relative to the ground state, all observed levels shift to lower energies as the temperature increases. Most lines show the usual shifts to the red. All these effects are qualitatively attributable to lattice vibrations. In general, the level shifts increase for the higher levels so that, ordinarily, line shifts are to the red with increasing temperatures. However, because of irregularities of the magnitudes of the level shifts, a few lines show shifts to the blue with increasing temperature, over some temperature ranges.
PO-274 Tumour subtype-specific cells of origin of malignant mesothelioma (2018)

Introduction Malignant Mesothelioma (MM) is an aggressive malignancy of the lining of the thoracic and peritoneal cavity. The primary cause is previous asbestos exposure. The pathological diagnosis of MM is rather complex due to a lack of useful biological markers and because multiple cell types are involved in the development of MM. We aimed to investigate to what extent the tumour subtype is determined by the cell of origin rather than the somatically acquired driver mutations. Material and methods Co-deletion of the conditional tumour suppressors, NF2, p53 and Cdkn2a in freshly isolated mesothelial cells using Cre viruses allowed us to establish clonal cell lines with epithelial, sacomatoid and biphasic morphology as also observed in human MM. Cells were analysed for clinical relevant protein marker profiles, tumorigenic potential and RNA expression. Results were compared to (poly)clonal cell lines obtained from conditional mice injected intra-thoracically with lentiviruses expressing Cre-recombinase driven by tissue-specific promoters. Results and discussions Using the ex vivo approach we were able to obtain clonal cell lines that upon transplantation gave rise to the main three MM tumour epithelial, sarcomatoid and biphasic subtypes. The epithelial and sarcomatoid phenotypes observed in vitro retained in the tumours, also after serial transplantation of the cell lines. Clonal biphasic cells co-expressed both epithelial and sarcomatoid markers and external factors could skew these biphasic cells towards a more epithelial or sarcomatoid phenotype. Transplantation of clonal biphasic cells only gave rise to tumours when the cells were grafted in immune-deficient mice, this in contrast to the epithelial and sarcomatoid cell lines that effectively gave tumours in syngeneic immunocompetent recipients. Analysis of tumour cell populations and derived clonal cell lines induced by lentiviral Cre-mediated switching of the same tumour suppressors in the mesothelial lining of conditional mice showed a high level of heterogeneity that included the same tumour subtypes also obtained using the ex vivo procedure. Conclusion A set of the same genetic mutations is able to drive heterogeneous MM development suggesting that the specific phenotype of the resulting tumour depends on the specific cell-of-origin. Therefore, epigenetic differences rather than acquired mutations appear a determining factor for the subtype of MM that arises. This epigenetic state appears relative stability as interconversion of the tumour subtypes was not observed.
CONCURRENT TESTING OF FLOW OF CONTROL IN SIMPLE MICROPROGRAMMED CONTROL UNITS. (1982)

Retroviral vectors have been constructed for gene transfer in mammalian and avian cells, however most retroviral vector systems are complicated by the spread of a replication-competent helper virus. This problem has been circumvented by segregating the viral genome into cis- and trans-acting components. By establishing helper cell lines that produce the trans-acting viral gene products, one can propagate the cis-acting component in them and harvest defective viral particles that contain only the cis-acting component. The cis-acting component can provide a useful vehicle for the highly efficient transfer of genes into target cells. The defective vector systems described to date, however, are restricted in host range to murine, avian, rat, and dog cells. We describe a helper-free vector system based entirely on an amphotropic murine virus with a wide mammalian host range, including the ability to carry out efficient gene transfer into human cells. We also describe a double mutation constructed in the trans-acting genome which reduces the frequency of replication-competent recombinant viruses to undetectable levels.
Numerical calculation of mine pressure in deep immerged tunnel of protection layer mining (2011)

The mining face in the Twelve Mine belong to Pingdingshan Colliery Group Co. LTD is immerged in the depth of 1015m between 1130m. Extraction Scheme of Protective Seams was used as the key technology. So the law of mine pressure in the tunnel below should be further researched. To the actual actual conditions, the three-dimensional model was build using the FLAC3D. The mine pressure in the tunnel below was calculated. From the result of calculation it was showed that the mine pressure of the tunnel below decreased after mining. But before and while mining the mine pressure increased and the tunnel was difficult to support. The tunnel on the side of mining area was under the long term load of mining and the pressure in the surround rock was very large. To the different variation patterns, the pertinence solutions should be taken to maintain the stability of the tunnels.
Designing of an intelligent temperature cum humidity monitoring system (2015)

The current study describes the designing of an intelligent temperature cum humidity monitoring system. The system is capable of alerting the user via short message service (SMS) in eventuality of a critical event as defined by the user. Additionally, the device can wirelessly log the data in a computer. There is a need for such kind of devices in agricultural, pharmaceutical and biomedical industries. In either of these industries mentioned above, there is a need for aprecise control of the temperature and humidity. Any deviation from the controlled environment may lead to financial (agricultural, pharmaceutical and biomedical industries) losses. Our proposed device may help in immediately altering the user. The immediate intervention of the user may reduce the loss. The prototype device was successfully tested under simulated varying environmental conditions.
Clinical Management of Attention Deficit Hyperactivity Disorder (1991)

This article reviews current approaches to the diagnosis and management of children with attention deficit hyperactivity disorder in a multidisciplinary setting. The physician's role in terms of data collection, formulation of the diagnosis, and discussion of findings with the parents and child is reviewed. The use of psychostimulants in this condition is reviewed, and some case vignettes are presented.
Laser Beam Shaping Applications (2017)

Preface Illuminators for Microlithography, Paul Michaloski Laser Beam Shaping in Array-Type Laser Printing Systems, Andrew F. Kurtz and Daniel D. Haas Practical UV Excimer Laser Image System Illuminators, Jeffrey P. Sercel and Michael von Dadelszen Beam Shaping for Optical Data Storage, Edwin P. Walker and Tom D. Milster Isotope Separation with Infrared Laser Beams, Andrew Forbes and Lourens Botha Laser Beam Shaping by Means of Flexible Mirrors, T.Yu. Cherezova and A.V. Kudryashov Application of Laser Beam Shaping for Spectral Control of Spatially Dispersive Lasers, I.S Moskalev, V.V. Fedorov, S.B. Mirov, T.T. Basiev, and P.G. Zverev Beam Shaping: A Review, Fred M. Dickey and Scott C. Holswade History of Beam Shaping, David L. Shealy Index
MicroRNA expression profiling in the lungs of genetically different Ri chicken lines against the highly pathogenic avian influenza H5N1 virus (2023)

The highly pathogenic avian influenza (HPAI) virus triggers infectious diseases, resulting in pulmonary damage and high mortality in domestic poultry worldwide. This study aimed to analyze miRNA expression profiles after infection with the HPAI H5N1 virus in resistant and susceptible lines of Ri chickens.For this purpose, resistant and susceptible lines of Vietnamese Ri chicken were used based on the A/G allele of <i>Mx</i> and <i>BF2</i> genes. These genes are responsible for innate antiviral activity and were selected to determine differentially expressed (DE) miRNAs in HPAI-infected chicken lines using small RNA sequencing. A total of 44 miRNAs were DE after 3 days of infection with the H5N1 virus. Computational program analysis indicated the candidate target genes for DE miRNAs to possess significant functions related to cytokines, chemokines, MAPK signaling pathway, ErBb signaling pathway, and Wnt signaling pathway. Several DE miRNA-mRNA matches were suggested to play crucial roles in mediating immune functions against viral evasion. These results revealed the potential regulatory roles of miRNAs in the immune response of the two Ri chicken lines against HPAI H5N1 virus infection in the lungs.
Communication Protocol for Enabling Continuous Monitoring of Elderly People through Near Field Communications (2013)

Continuous and wireless transmission of vital signs for personalized healthcare is gaining a great deal of interest from Ambient Assisted Living solutions. Personalized healthcare capabilities are limited to the patient data available, which is usually dynamic and incomplete. For that reason, regular monitoring of patients with the aim of offering a suitable analysis of patient evolution is required. Continuous monitoring requires the integration of wireless communication technologies and embedded systems into wearable and portable monitoring systems. In addition, a user interface intuitive is also required, which is easy to use and understand by the patients and caregivers. This work proposes a solution such as Near Field Communication (NFC) for personalized healthcare based on the Internet of Things. NFC is a technology integrated in smart phones that provides capabilities for identification of devices/sensors, and presents ubiquitous communication capabilities between the sensor and the device. NFC also presents challenges in terms of the performance and efficiency of data transmission, due to the constrained resources and capabilities of ubiquitous devices and the latency introduced by the NFC technology. These challenges are intrinsic to NFC since it was originally considered only for simple identification and not for continuous data transmission. In this context, this paper presents a novel monitoring system for continuous data transmission from a set of clinical devices based on NFC which has been optimized in order to make communications feasible. This novel monitoring system is also composed by a set of participatory sensing applications to support caregivers and for patients to self-monitor and self-manage their health status wirelessly. A technical evaluation based on latencies associated with use of NFC for continuous monitoring and an evaluation of usability by a group of elderly users and their caregivers, which studies the interactions between the users and the system, are demonstrated.
A multimedia database system for 3D crime scene representation and analysis (2007)

The development of sensors capable of obtaining 3D scans of crime scenes is revolutionizing the ways in which crime scenes can be analyzed and at the same time is driving the need for the development of sophisticated tools to repre-sent and store this data. Here we describe the design of a multimedia database suitable for representing and reason-ing about crime scene data. The representation is grounded in the physical environment that makes up the crime scene and provides mechanisms for representing both traditional (forms-based) data as well as audiovisual (3D scan and other complex spatial data). Some initial results obtained with tools designed to seed the dataset are reported as well as some components of the final database system. 1.