gebhart/patrepeval huggingface dataset:
Data Aggregation Scheme for a Mashup Based Internet Application (2011)

This paper discusses a data aggregation scheme based on the query results by using a mashup technique. We propose system architecture for seamlessly integrating a portal for end-user and a data analysis application. The system architecture is applied to a mashup application for analyzing stock portfolio to integrate an Internet-based application and data analysis application. In the application, we use Protocol Buffer to define the data structure representing a message signature, Me cached to maintain the result of end-user query and NaradaBroker, pub/sub based middleware, to connect loosely with sub systems. To evaluate performance of system, we compare the size of messages written in different data formats. In the evaluation, we perform a TPC-based benchmark to evaluate caching effect.
Tumor necrosis factor modulates Ca2+ currents in cultured sympathetic neurons (1992)

The effect of recombinant human tumor necrosis factor-alpha (rhTNF) on calcium currents of cultured neurons from neonatal rat superior cervical ganglia (SCG) was studied using whole-cell patch-clamp technique. We found that rhTNF-treated SCG neurons exhibited increased calcium current density without significant alteration in the steady-state parameters of activation and availability. The fraction of the current sensitive to dihydropyridines and omega-conotoxin also remained unchanged. Recovery from slow inactivation of the current, but not recovery from fast inactivation, was prolonged in rhTNF-treated cells when compared to that of control cells. We conclude that immune peptides such as rhTNF can alter cellular functions of sympathetic neurons via modulating ionic conductances. However, these changes observed in calcium currents of SCG neurons cannot account for the effect of rhTNF on norepinephrine secretion observed in a previous study. It is proposed that rhTNF exerts an additional effect at a later event in the exocytotic process.
Multiple Orthokeratinized Odontogenic Cysts: A Report of Two Cases and Review of the Literature (2019)

Orthokeratinized odontogenic cysts (OOC) are developmental odontogenic cysts characterised by an orthokeratinized stratified squamous epithelial lining. They were originally believed to be part of the spectrum of Odontogenic Keratocyst, but are now considered to be a distinct entity. They are rare, making up approximately 1% of all odontogenic cysts and they usually occur singly. In this paper we present two new cases of multiple OOCs, and compare them to previous case reports of multiple lesions. The clinical and pathological features are discussed, along with possible diagnostic pitfalls.
System considerations for robust time and space partitioning in Integrated Modular Avionics (2008)

Developers face many difficult and unique challenges when designing Integrated Modular Avionics (IMA) systems employing robust time and space partitioning as defined by the ARINC 653 open standard. Several such IMA system design challenges are posed by common hardware features such as interrupts, Direct Memory Access (DMA), and system Input/Output (I/O), as they may produce unpredictable distortions that violate the constraints of time and space partitioning. Time and space partitioning must be deterministic in an ARINC 653-based IMA system in order to avoid aircraft certification concerns and incompatibilities with the standards and guidelines set forth in DO-178B. Methods for identifying, analyzing, and rectifying potential determinism issues in the IMA system are presented herein. A sample system employing Wind Riverpsilas VxWorks 653 real-time operating system is used to empirically demonstrate determinism issues and how to overcome them, resulting in a certifiable IMA system which effectively uses hardware resources.
Transformation of Lotus japonicus using the herbicide resistance bar gene as a selectable marker (2001)

Transgenic plants of the model legume Lotus japonicus were regenerated by hypocotyl transformation using a bar gene as a selectable marker. The bar encodes for Phosphinothricin Acetyl Transferase that detoxifies phosphinothricin (PPT), the active ingredient of herbicides such as Ignite (AgrEvo) and Basta (Hoechst). Transgenic L. japonicus plants resistant to PPT were positive upon PCR by bar gene‐specific primers. In 5 out of 7 independent lines tested, PPT resistance segregated as a single dominant allele indicating a single T‐DNA insertion into the plant genome. All regenerated plants were fertile and void of visible somaclonal abnormalities contrary to 14% infertility when antibiotic selectable markers were used. The lack of somaclonal variation, ease of PPT application and low cost of PPT makes this protocol an attractive alternative for the regeneration of transgenic L. japonicus . The production of PPT herbicide‐resistant L. japonicus plants may have significant commercial applications in crop production.
An Implementation of FTTH based Home Gateway supporting Various Services (2006)

HG (home gateway) is an interface device that connects an access network, WAN (wide area network), to a home network. FTTH (fiber to the home) based HG is an HG with FTTH network as an access network interface. In this paper, we propose an implementation of FTTH based HG, specially EPON (Ethernet passive optical network) based HG. With the FTTH access network interface, the proposed HG can provide service bandwidth of 100 Mbps to 1 Gbps to each subscriber. The amount is enough bandwidth to provide various home network services for each one. Our proposed HG has a novel architecture with various home network interfaces and can use efficiently the abundant bandwidth for the various services.
Antimetastatic Activity of a Preventive Cancer Vaccine (2007)

The development of prophylactic cancer vaccines that protect healthy hosts from tumor development leaves open the question whether such vaccines are also effective against established tumors and metastases. We tested the therapeutic activity of a proven prophylactic anti-HER-2/neu vaccine against successive stages of mammary carcinoma progression in HER-2/neu transgenic mice. The vaccine consisted of transgenic mammary carcinoma cells expressing HER-2/neu and two adjuvants: allogeneic class I histocompatibility antigens and interleukin (IL)-12. Vaccination of mice bearing lung micrometastases resulted in a 90% inhibition of metastasis development, whereas vaccination of mice with incipient local tumors was ineffective. The antimetastatic response was hampered by immune tolerance, as the protection of transgenic mice was lower than that of wild-type congenics not tolerant to HER-2/neu. A significant gain in immunotherapeutic activity in transgenic mice was obtained through the coadministration of anti-CD25 monoclonal antibody targeting regulatory T cells, which resulted in a >99% inhibition of metastasis. The immune responses elicited in transgenic mice comprised the activation of lung granulocytes and macrophages and of systemic adaptive responses based on helper T cells and their cytokines (IFN-gamma and IL-4) and anti-HER-2/neu antibodies. Dissection of relevant antimetastatic mechanisms by means of knockout mice and of depleting antibodies revealed a major difference between tumor prevention, which was completely dependent on anti-HER-2/neu antibodies, and metastasis therapy, which was antibody independent. In conclusion, a vaccine successfully developed for cancer immunoprevention showed a strong therapeutic activity against lung metastases mediated by protective immune mechanisms distinct from those preventing the onset of primary mammary carcinoma.
Mg(OH)2 Complex Nanostructures with Superhydrophobicity and Flame Retardant Effects (2010)

Complex Mg(OH)2 nanostructures are synthesized via a biomolecule-assisted hydrothermal route. The as-synthesized Mg(OH)2 nanostructures are dispersed into an acrylonitrile-butadiene-styrene (ABS) copolymer by mechanical kneading, which shows an excellent flame-retardant behavior. Also we demonstrated for the first time that the complex Mg(OH)2 nanostructures can find application in self-cleaning for its superhydrophobicity with water contact angle over 150° and sliding angle of 1°.
Minimizing distortion via multiuser resource allocation (2003)

Summary form only given. Source-controlled resource allocation is investigated for orthogonal transmission of heterogenous sources over a multiuser system. Different scenarios are considered where the system resources rate, bandwidth, and power are shared among all users in such a way that the average distortion over all users is minimized. This may prove beneficial to understand the trade-offs in mobile communication broadcast scenarios where common system resources are allocated depending on the instantaneous application needs. In a mobile communications environment, the channels to the users affect the transmitted signal differently so that rates cannot be traded for each other but bandwidth and transmission time are fairly easy tradable.
Cognitive Style and Concept Mapping Performance (2015)

Abstract Background Cognitive style has been shown to influence the number, type, and organization of an individual's ideas. Concept maps are used regularly to assess students’ organization and mastery of knowledge (their cognitive level) in engineering courses, yet very few studies have analyzed concept maps with respect to cognitive style. Purpose/Hypothesis This study sought to investigate the relationship between cognitive style and concept mapping performance. Using principles of cognitive psychology and concept mapping assessment, we hypothesized that correlations between cognitive style and the selected concept map metrics are not statistically significant. Design/Method Concept maps from 104 engineering undergraduates in a first‐year design course were analyzed using 12 traditional scoring metrics and four holistic scoring metrics. One holistic metric was expanded to allow more detailed evaluation, bringing the number of map metrics to 20. Cognitive style was measured using the Kirton Adaption–Innovation Inventory, a psychometric instrument previously applied in engineering education contexts. Relationships between the concept map metrics and cognitive style were investigated using standard linear techniques. Results Results show substantial support for the null hypothesis that cognitive style and concept mapping performance are uncorrelated. Conclusions Engineering educators can be confident that the concept map metrics used here reflect cognitive level and not cognitive style. Cognitive style inventories and concept maps are likely measuring two separate aspects of an individual's cognition and are therefore complementary rather than duplicative.
Continuing Advancements in In-Core Power Distribution Measurement Methods Using SIMULATE-3 and CECOR 3.4 (1995)

AbstractA method for the generation of in-core constants from the SIMULATE-3 advanced reactor analysis code is presented. This method builds on prior work at the Southern California Edison Company for the San Onofre Nuclear Generating Station and is now applied to the Combustion Engineering System 80 units at the Palo Verde Nuclear Generating Station (PVNGS). Power-to-signal ratios, assembly coupling coefficients, pin peaking factors, and Fourier Series analysis are shown to reproduce the SIMULATE-3 solution extremely well. Correction of SIMULATE-3 calculated in-core detector fluxes and cross sections for rhodium shielding and homogeneous-to-heterogeneous geometries are discussed. Calculated and measured detector signals are compared to confirm the ability to calculate the rhodium reaction rates needed for the power-to-signal ratio and are found to be within 2%.Core maximum power peaking factors and a radial assembly power distribution for PVNGS Unit 3 cycle 5 show excellent agreement with differences <2% in maximum power locations. This work is the basis for future improved reactor surveillance methods, with the realization of significant thermal margin gains from reduced uncertainties in the core protection system.
Alkyne‐Mediated Approach for Total Syntheses of Cladospolides A, B, C and iso‐Cladospolide B (2013)

Abstract A general strategy for the stereoselective total syntheses of cladospolides A, B, and C and iso ‐cladospolide B has been accomplished. The key steps provide easy access to the target molecules and include an alkyne‐zipper reaction, a Sharpless asymmetric epoxidation/dihydroxylation, and a Yamaguchi macrolactonization. The feasibility of the alkyne‐mediated approach to construct the required carbon framework as well as to create the diol functionality and the olefin geometry is successfully demonstrated.
T-wave oversensing and inappropriate shocks: a case report (2008)

A 27-year-old male with congenital long QT syndrome, SCN5A mutation experienced recurrent inappropriate exercise-related implantable cardioverter defibrillator (ICD) shocks. This device showed T-wave oversensing with double, which lead to these device discharges. Dynamic T-wave oversensing was reproducibly provoked at exercise treadmill testing and was confirmed as the mechanism leading to double counting. The insertion of a new pacing and sensing lead with increased R-wave amplitude did not solve the problem. Exchanging the existing ICD generator with one capable of automatic sensitivity control (Biotronik, Lexos DR, Biotronik, Berlin, Germany) completely eliminated T-wave oversensing and inappropriate shocks.
ChemInform Abstract: BIOMIMETIC APPROACH TO THE SYNTHESIS OF LAURENCIA METABOLITES. SYNTHESIS OF 10‐BROMO‐α‐CHAMIGRENE (1976)

Abstract Geranylacetat (I) liefert mit N‐Bromsuccinimid in wäßrigem Glykoldimethyläther das Bromhydrin (III) über das Bromoniumion (II), während mit Brom und Zinntetrabromid in Nitromethan über (II) und (IV) das Cyclisierungsprodukt (V) gebildet wird.
<title>Antistiction coatings for surface micromachines</title> (1998)

Adhesion, friction, and wear are prevalent problems in a majority of MEMS devices. Understanding of surface interactions in MEMS is of paramount importance for controlling stiction phenomena. This paper will discuss various surface treatments employed to reduce adhesion and friction in polysilicon-based MEMS, their successes and their limitations.
Strained n-Channel FinFETs Featuring In Situ Doped Silicon–Carbon $(\hbox{Si}_{1 - y}\hbox{C}_{y})$ Source and Drain Stressors With High Carbon Content (2008)

Phosphorus <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">in</i> <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">situ</i> doped (Si <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1-y</sub> C <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">y</sub> ) films (SiC:P) with substitutional carbon concentration of 1.7% and 2.1% were selectively grown in the source and drain regions of double-gate -oriented (110)-sidewall FinFETs to induce tensile strain in the silicon channel. <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">In</i> <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">situ</i> doping removes the need for a high-temperature spike anneal for source/drain (S/D) dopant activation and thus preserves the carbon substitutionality in the SiC:P films as grown. A strain-induced enhancement of 15% and 22% was obtained for n-channel FinFETs with 1.7% and 2.1% carbon incorporated in the S/D, respectively.
Statistically regulated and adaptive EM reconstruction for emission computed tomography (2001)

Iterative algorithms such as MLEM are rapidly becoming the standard for reconstruction in emission computed tomography. However, such algorithms require arbitrary stopping criteria, are sensitive to noise artifacts, and require accelerated implementations that may not work well for all imaging situations. We have investigated several new iterative algorithms with likelihood-based objective functions that use the concepts of statistically adaptive subsetting and spatially adaptive updates. The resulting statistically regulated expectation maximization (StatREM) algorithms are closely related to OSEM with the following exceptions: they apply spatially adaptive regularization and use statistically adaptive subsets to accelerate convergence in a controlled manner. Projection data are processed sequentially and internal statistically adaptive subsets are formed. When accumulated statistical power merits an update, e.g., determined by paired sample t-test, then spatially adaptive updates are applied and the corresponding test statistics and subset accumulations are reset. Reconstruction continues iteratively until no further statistically significant errors remain. The following properties were observed for clinical, phantom and simulated data: (1) user-defined test levels can provide statistically based stopping criteria; (2) recovery of spatial resolution is accelerated in high-count regions while low-count regions are regulated to reduce noise artifacts; (3) notable acceleration is achieved for large, sparse datasets [such as fully 3-D positron emission tomography (PET)]; and (4) resolution and contrast are superior to conventional OSEM at much lower noise levels. Statistically regulated expectation maximization algorithms may potentially provide a new archetype for PET and SPECT reconstruction.
Development of a teleoperated backhoe for buried waste excavation (1992)

For nearly five decades the United States (US) Department of Energy (DOE) and its predecessor agencies have engaged in broad-based research and development activities as well as nuclear weapons component production. As a by-product of these activities, large quantities of waste materials have been granted. One of the most common approaches used for solid waste storage was to bury waste containers in pits and trenches. With the current emphasis on environmental restoration, DOE now plans to either retrieve much of the legacy of buried waste or stabilize the waste in place via in situ vitrification or other means. Because of the variety of materials that have been buried over the years, the hazards of retrieval are significant if performed using conventional manned operations. The potential hazards, in addition to radiation exposure, include pyrophorics, toxic chemicals, and explosives. Although manifests exist for much of the buried waste, these records are often incomplete compared to today's requirements. Because of the potential hazards and uncertainty about waste contents and container integrity, it is highly desirable to excavate these wastes using remotely operated equipment. In this paper the authors describe the development of a teleoperated military tractor called the Small Emplacement Excavator (SEE). Developmentmore » of the SEE is being funded jointly by both DOE and the US Army. The DOE sponsor is the Office of Technology Development (OTD) Robotics Program. The US Army sponsor is the Program Manager for Ammunition Logistics, Picatinny Arsenal. The primary interest for DOE is in the application to remote excavation of buried waste, while the primary emphasis for the US Army is in the remote retrieval of unexploded ordnance. Technical requirements for these two tasks are very similar and, therefore, justify a joint development project. 1 ref.« less
Dynamics of transcriptomic response to infection by the nematode Heterorhabditis bacteriophora and its bacterial symbiont Photorhabdus temperata in Heliothis virescens larvae (2017)

Entomopathogenic nematodes in the Heterorhabditis genus and their symbiotic Photorhabdus bacteria are important biocontrol agents of insect pests and models for the study of microbe-host interactions. In this work, we used larvae of the tobacco budworm (Heliothis virescens) as a model to study its defensive mechanisms against Heterorhabditis bacteriophora nematodes carrying symbiotic Photorhabdus temperata. We first determined time points of initial nematode entry and release of bacteria into the haemolymph to perform transcriptional analysis of insect gene expression during these steps in the infective process. RNA-Sequencing analyses were then performed to profile differential gene expression in the insect during nematode invasion, bacterial release and final steps of infection, relative to the untreated controls. Our results support the theory that insect immune response genes are induced upon nematode invasion, but the majority of these genes are suppressed upon the release of bacteria by the nematodes into the haemolymph. Overall, these findings provide information on the dynamics of the insect's response to a progressing infection by this entomopathogenic nematode-bacteria complex and facilitate development of Hel. virescens as a pest model for future functional studies of the key insect defence factors.
Structure-function analysis of the integrin beta 7 subunit: identification of domains involved in adhesion to MAdCAM-1 (1997)

Beta 7 integrins serve special roles in mucosal immunity. Alpha 4 beta 7-mediated adhesion to mucosal addressin cell adhesion molecule-1 (MAdCAM-1) directs lymphocyte homing to the gut, and alpha E beta 7 mediates binding of lymphocytes to E-cadherin on epithelial cells. Since alpha 4 beta 7 mediates adhesion to MAdCAM-1 but alpha 4 beta 1 does not, we used beta 7/beta 1 chimeras to directly assess the importance of specific regions of beta 7 in MAdCAM-1 binding. We found a region of beta 7 (residues 46-386) that accounts for specificity of alpha 4 beta 7 binding to MAdCAM-1. We also used human/mouse and human/rat chimeric beta 7 subunits to map epitopes recognized by fifteen anti-beta 7 mAbs. Six of seven Abs that block adhesion to MAdCAM-1 and E-cadherin (Fib 21, 22, 27, 30, 504; Act-1) mapped to amino acid residues 176-250. Residues 176-250 lie within the region of beta 7 that specifies MAdCAM-1 binding and also within a region that has a predicted structure homologous to the metal ion-dependent adhesion site (MIDAS) domains of the integrin subunits alpha L and alpha M. Three new Abs that recognize beta 7 in the presence of Mn2+, but not Ca2+, and promote adhesion to MAdCAM-1, mapped to amino acids 46-149. One blocking and five other Abs mapped to other regions (amino acids 387-725). We conclude that a MIDAS-like domain serves a critical role in beta 7 integrin-mediated adhesion.
EISL, the Pendant to EIRP: A Measure for the Receive Performance of Base Stations at the Air Interface (2002)

This paper presents a new method to compare the receiving performance of different types of base stations (BS) in consideration of their architecture, the system noise and the antenna performance. The usual measure to indicate the transmitting performance and coverage of a BS is the equivalent isotropic radiated power (EIRP). On the receiving side, no such measure has so far been introduced. Active antennas with down tilt features, the received noise and noise, which is added at different locations in the signal path as well as varying RF-front-end-architectures make it difficult to compare the sensitivity of different base station architectures. Therefore a new measure will be introduced in this paper, the so-called equivalent isotropic sensitivity level (EISL). This measure makes it possible to compare different types of base station architectures in terms of their real sensitivity right at the air interface with respect to the system architecture and noise. Finally, EISL will be used to compare different base station concepts and to show the influence of the antenna down tilt on the effective usable sensitivity of a base station.