gebhart/patrepeval huggingface dataset:
RcUBe: Real-time reconfigurable radio framework with self-optimization capabilities (2015)

Existing commercial wireless systems are mostly hardware-based, and rely on closed and inflexible designs and architectures. Moreover, despite recent significant algorithmic developments in cross-layer network adaptation and resource allocation, existing network architectures are unable to incorporate most of these advancements. While software-defined radio (SDR) was envisioned as a new paradigm promising radical runtime adaptation through all layers of the networking protocol stack, the reality of the state-of-the-art in wireless networking practice is far from having fulfilled such promise of fast and intelligent reconfigurability and adaptability. Networking research based on the “software-defined radio” paradigm has suffered almost invariably from the lack of adequate and coherently designed abstractions to (i) define networking protocols and their cross-layer interactions across all layers of the protocol stack; (ii) define decision-making algorithms to control such interactions. To address this need, we introduce RcUBe (Real-time Re-configurable Radio), a novel architectural radio framework based on abstractions that offer real-time reconfigurability and optimization capabilities at the PHY, MAC, and network layers of the protocol stack. Unlike state-of-the-art solutions, RcUBe offers a structured methodology at variable levels of abstraction to accommodate implementations of a wide range of network architectures and protocols and complex decision-making in a modular, platform-independent way. RcUBe provides these features through a design structured into four distinct, but interacting planes, namely decision, control, data, and register plane. The broad capabilities of the proposed framework are demonstrated on a network level software-defined radio setup through a range of experiments where RcUBe is used to implement various reconfigurable functionalities of a wireless system at the PHY, MAC, and network layer.
Identification of in Vivo Disulfide Conformation of TRPA1 Ion Channel (2011)

TRPA1 (transient receptor potential ankyrin 1) is an ion channel expressed in the termini of sensory neurons and is activated in response to a broad array of noxious exogenous and endogenous thiol-reactive compounds, making it a crucial player in chemical nociception. A number of conserved cysteine residues on the N-terminal domain of the channel have been identified as critical for sensing these electrophilic pungent chemicals, and our recent EM structure with modeled domains predicts that these cysteines form a ligand-binding pocket, allowing for the possibility of disulfide bonding between the cysteine residues. Here, we present a comprehensive mass spectrometry investigation of the in vivo disulfide bonding conformation and in vitro reactivity of 30 of the 31 cysteine residues in the TRPA1 ion channel. Four disulfide bonds were detected in the in vivo TRPA1 structure: Cys-666-Cys-622, Cys-666-Cys-463, Cys-622-Cys-609, and Cys-666-Cys-193. All of the cysteines detected were reactive to N-methylmaleimide (NMM) in vitro, with varying degrees of labeling efficiency. Comparison of the ratio of the labeling efficiency at 300 μM versus 2 mM NMM identified a number of cysteine residues that were outliers from the mean labeling ratio, suggesting that protein conformation changes rendered these cysteines either more or less protected from labeling at the higher NMM concentrations. These results indicate that the activation mechanism of TRPA1 may involve N-terminal conformation changes and disulfide bonding between critical cysteine residues.
Modeling latent biographic attributes in conversational genres (2009)

This paper presents and evaluates several original techniques for the latent classification of biographic attributes such as gender, age and native language, in diverse genres (conversation transcripts, email) and languages (Arabic, English). First, we present a novel partner-sensitive model for extracting biographic attributes in conversations, given the differences in lexical usage and discourse style such as observed between same-gender and mixed-gender conversations. Then, we explore a rich variety of novel sociolinguistic and discourse-based features, including mean utterance length, passive/active usage, percentage domination of the conversation, speaking rate and filler word usage. Cumulatively up to 20% error reduction is achieved relative to the standard Boulis and Ostendorf (2005) algorithm for classifying individual conversations on Switchboard, and accuracy for gender detection on the Switchboard corpus (aggregate) and Gulf Arabic corpus exceeds 95%.
Pulmonary Edema After Absorbing Crystalloid Irrigating Fluid During Laparoscopy (1994)

Healzer, J. M. MD; Nezhat, C. MD; Brodsky, J. B. MD; Brock-Utne, J. G. MD; Seidman, D. S. MD Author Information
"MyEyes" (2017)

Couples in Long Distance Relationships (LDRs) often rely on the use of video chat systems to help maintain their relationship. However, designs are typically limited to only supporting face-to-face conversations or providing narrow fields of view. We designed and evaluated MyEyes, a First Person View (FPV) video streaming technology probe made with cardboard goggles and a smartphone. Distance-separated partners see each other's view on their screen where it can overlap their own view (Overlapped), be placed above it (Horizontal), or presented at the same time where each is seen with a different eye (Split). We compared the three different views with couples to explore the effect on social presence and body ownership. The Overlapped View was most preferred by couples and it provided the strongest feeling of co-presence, whereas a Horizontal View provided the greatest sense of mutual understanding. Our qualitative results showed couples valued performing synchronized acts together and doing activities "in" the remote location.
Mechanism of action of ribavirin in the treatment of chronic hepatitis C. (2007)

The current standard treatment for chronic hepatitis C consists of the combination of pegylated interferon and ribavirin. Although interferon is known to have potent antiviral, immunomodulatory, and anti-inflammatory activities against hepatitis C, the mechanism of ribavirin action against this virus is not clearly understood. This article will review proposed mechanisms of ribavirin activity, along with their supporting data, covering ribavirin's roles in the direct inhibition of hepatitis C viral replication, the inhibition of inosine monophosphate dehydrogenase, the induction of mutagenesis to the threshold of error catastrophe, and immunomodulation.
A Holistic Multimedia System for Gastrointestinal Tract Disease Detection (2017)

Analysis of medical videos for detection of abnormalities and diseases requires both high precision and recall, but also real-time processing for live feedback and scalability for massive screening of entire populations. Existing work on this field does not provide the necessary combination of retrieval accuracy and performance.; [email protected] this paper, a multimedia system is presented where the aim is to tackle automatic analysis of videos from the human gastrointestinal (GI) tract. The system includes the whole pipeline from data collection, processing and analysis, to visualization. The system combines filters using machine learning, image recognition and extraction of global and local image features. Furthermore, it is built in a modular way so that it can easily be extended. At the same time, it is developed for efficient processing in order to provide real-time feedback to the doctors. Our experimental evaluation proves that our system has detection and localisation accuracy at least as good as existing systems for polyp detection, it is capable of detecting a wider range of diseases, it can analyze video in real-time, and it has a low resource consumption for scalability.
Stacking in the time‐scale plane (2002)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 2002Stacking in the time‐scale planeAuthors: Antoine RoueffJocelyn ChanussotJéro⁁me MarsGuy CanadasAntoine RoueffLaboratoire des Images et des Signaux, INP of Grenoble, France, Jocelyn ChanussotLaboratoire des Images et des Signaux, INP of Grenoble, France, Jéro⁁me MarsLaboratoire des Images et des Signaux, INP of Grenoble, France, and Guy CanadasTotalFinaElf, Pau, Francehttps://doi.org/10.1190/1.1817178 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1817178FiguresReferencesRelatedDetails SEG Technical Program Expanded Abstracts 2002ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 2002 Pages: 2478 publication data© 2002 Copyright © 2002 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished Online: 03 Jan 2005 CITATION INFORMATION Antoine Roueff, Jocelyn Chanussot, Jéro⁁me Mars, and Guy Canadas, (2002), "Stacking in the time‐scale plane," SEG Technical Program Expanded Abstracts : 2317-2320. https://doi.org/10.1190/1.1817178 Plain-Language Summary PDF DownloadLoading ...
Improving Breast Cancer Detection Accuracy of Mammography with the Concurrent Use of an Artificial Intelligence Tool (2020)

This clinical investigation demonstrated that the concurrent use of this AI tool improved the diagnostic performance of radiologists in the detection of breast cancer without prolonging their workflow.<i>Supplemental material is available for this article.</i>© RSNA, 2020.
Dynamic Response of Footings to Vertical Loading (1966)

The objective of this paper is to describe the dynamic behavior of footings and to develop practical methods for dynamic analysis. The investigations are limited to the case of a rigid circular footing resting on a plane soil surface and excited by a vertical time-dependent force in the axis of symmetry.
Dominosequenzen zur Darstellung etherverbr�ckter, polycyclischer Mono- und Bipyridine (1998)

Synthesis of Ether-bridged, Polycyclic Mono- and Bipyridines by Domino Reactions On the basis of iminium salt chemistry, an inexpensive one-pot reaction provides novel ether-bridged, polycyclic mono-and bipyridines. This domino reaction sequence succeeds using chromanone derivatives and β-amino ketone hydrochlorides (or free mannich bases) in the presence of ammonium acetate. The strategy offers a great flexibility in the design of new structures of this type (5a–b, 6a–c and 8) and underlines the efficiency of domino reactions.
Remote robotic technology development for the new plutonium production facility (1989)

The Savannah River Laboratory (SRL) in Aiken, South Carolina, is developing remote robotics technology, in conjunction with the Savannah River Plant (SRP), to support a new generation of plutonium production facilities. The present conventional glove box facilities are based on 1950's design technology and are obsolete. Future potential process changes and possible additional tasks increase the need for a newer technology facility. The design objectives for the new facilities are to minimize personnel exposure, both operating and maintenance, and to maximize SNM accountability and safeguards. Therefore, the process systems would be contained in a totally remote environmental designed for no personnel entry over its lifetime. These concepts required new robotic and robotic interface technologies. The conceptual design is complete, and work is progressing in the development and demonstration phases. The robotic approaches taken are described in this paper, in the context of the overall facility design, which is specifically tailored for robotics. 4 figs.
An Experimental and Computational Study of Steel Moment Connections under a Column Removal Scenario (2010)

The policy of the National Institute of Standards and Technology is to use metric units in all its published materials.Because this report is intended for the U.S. building construction industry which uses in-pound units, it is more practical and less confusing to use inch-pound units, in some cases, rather than metric units within quoted text.However, in most cases, units are presented in metric and the inch-pound system.
Cinchona Derivatives as Bifunctional Organocatalysts for the Direct Asymmetric Nitroaldol (Henry) Reaction. (2006)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Constrained decomposition based control approach for linear parameter varying systems (2013)

Considering a constrained discrete-time linear time-varying system, this paper proposes a novel approach which aims at achieving high performance and enlarging the domain of attraction with respect to any particular linear controller. The main idea of the paper is to use a linear decomposition principle together with a parameter dependent Lyapunov function. At each time instant a quadratic programming problem is solved on-line. Proofs of recursive feasibility and asymptotic stability are given.
A DNA metabarcoding approach for recovering plankton communities from archived samples fixed in formalin (2021)

Plankton samples have been routinely collected and preserved in formalin in many laboratories and museums for more than 100 years. Recently, attention has turned to use DNA information from formalin-fixed samples to examine changes in plankton diversity over time. However, no molecular ecological studies have evaluated the impact of formalin fixation on the genetic composition of the plankton community structure. Here, we developed a method for extracting DNA from archived formalin-preserved plankton samples to determine their community structure by a DNA metabarcoding approach. We found that a lysis solution consisting of borate-NaOH buffer (pH 11) with SDS and proteinase K effectively cleaved the cross-link formed by formalin fixation. DNA was extracted from samples preserved for decades in formalin, and the diatom community of the extracted DNA was in good agreement with the microscopy analysis. Furthermore, we stored a plankton sample for 1.5 years and demonstrated that 18S rRNA gene community structures did not change significantly from non-formalin-fixed, time-zero samples. These results indicate that our method can be used to describe the original community structure of plankton archived in formalin for years. Our approach will be useful for examining the long-term variation of plankton diversity by metabarcoding analysis of 18S rRNA gene community structure.
Maximizing compression efficiency through block rotation (2014)

The Discrete Cosine Transform (DCT) is widely used in lossy image and video compression schemes, e.g., JPEG and MPEG. In this paper, we show that the compression efficiency of the DCT is dependent on the edge directions within a block. In particular, higher compression ratios are achieved when edges are aligned with the image axes. To maximize compression for general images, we propose a rotated block DCT method. It consists of rotating each block, before applying the DCT, by an angle that aligns the edges, and rotating back the block in the decompression stage. We show how to compute the rotation angle and analyze two alternative block rotation approaches. Our experiments show that our method enables both a perceptual improvement and a PSNR increase of up to 2dB, compared with the standard DCT, for low and medium bit rates.
GIV/Girdin activates Gαi and inhibits Gαs via the same motif (2016)

We previously showed that guanine nucleotide-binding (G) protein α subunit (Gα)-interacting vesicle-associated protein (GIV), a guanine-nucleotide exchange factor (GEF), transactivates Gα activity-inhibiting polypeptide 1 (Gαi) proteins in response to growth factors, such as EGF, using a short C-terminal motif. Subsequent work demonstrated that GIV also binds Gαs and that inactive Gαs promotes maturation of endosomes and shuts down mitogenic MAPK-ERK1/2 signals from endosomes. However, the mechanism and consequences of dual coupling of GIV to two G proteins, Gαi and Gαs, remained unknown. Here we report that GIV is a bifunctional modulator of G proteins; it serves as a guanine nucleotide dissociation inhibitor (GDI) for Gαs using the same motif that allows it to serve as a GEF for Gαi. Upon EGF stimulation, GIV modulates Gαi and Gαs sequentially: first, a key phosphomodification favors the assembly of GIV-Gαi complexes and activates GIV's GEF function; then a second phosphomodification terminates GIV's GEF function, triggers the assembly of GIV-Gαs complexes, and activates GIV's GDI function. By comparing WT and GIV mutants, we demonstrate that GIV inhibits Gαs activity in cells responding to EGF. Consequently, the cAMP→PKA→cAMP response element-binding protein signaling axis is inhibited, the transit time of EGF receptor through early endosomes are accelerated, mitogenic MAPK-ERK1/2 signals are rapidly terminated, and proliferation is suppressed. These insights define a paradigm in G-protein signaling in which a pleiotropically acting modulator uses the same motif both to activate and to inhibit G proteins. Our findings also illuminate how such modulation of two opposing Gα proteins integrates downstream signals and cellular responses.
High-Efficiency Transparent Small-Molecule Organic Light-Emitting Devices Adopting Laminated Transparent Top Electrodes (2015)

We demonstrate a highly efficient transparent small-molecule OLED with laminated top transparent electrode. This was made possible via the aid of the transparent conductive adhesive based on the conducting polymer PEDOT:PSS. With use of small-molecule materials and efficient phosphorescent emitters, rather high external quantum efficiency and current efficiency of up to (11.4%, 43.1 cd/A), comparable to the non-transparent non-laminated reference device and much higher than those in previously reported OLEDs using laminated top electrodes, were obtained. The transparent OLEDs exhibited rather balanced EL intensities and spectra from both sides of the devices, a broad optical transmission band, and a high optical transmittance of up to 77%. It provides a simple and yet effective approach for fabrication of efficient transparent OLEDs. It is not only useful for devices on rigid substrates by also can be extended to flexible devices or even roll-to-roll processes of such devices in future.
Fundamental Study on 2-propanol Dehydrogenation under Forced Periodic Temperature Cycling (2011)

化学反応プロセスを非定常な操作で行うことにより，定常操作を超える反応性を得られる可能性がある．2-プロパノールの脱水素反応をマイクロリアクターを用いて非定常な操作である温度周期操作で実施し，定常操作とその反応性の比較を行った．アルミニウム基板を陽極酸化した触媒プレートを用いて温度周期操作用のマイクロリアクターを作成し，温度周期操作の平均温度を150℃として変動周期を0.5 min，1 min，3 min，5 min，10 minと変動させて反応を行った．温度周期操作の結果，各周期において定常操作と比べて高い反応率が得られることがわかり，反応性は変動周期が大きいほど高くなることもわかった．また，反応器への供給電力を比較すると，同じ反応率を得るのに温度周期操作の方が定常操作に比べて供給電力を少なくできることがわかった．その減少率は変動周期が大きくなるほど大きいこともわかった．
Impact of aging on host immune response and survival in melanoma: an analysis of 3 patient cohorts (2016)

Older age at time of melanoma diagnosis is associated with shorter MSS, however age's association with clinicopathologic features is dependent upon specific characteristics of the study population. TIL as a read-out of the host immune response may have greater prognostic impact in patients older than age 45. Recognition of age-related factors negatively impacting host immune responses may provide new insights into therapeutic strategies for the elderly.
Gyrokinetic simulations of electrostatic microturbulence in ADITYA-U tokamak (2023)

Abstract Global gyrokinetic simulations of the electrostatic microturbulence driven by the pressure gradients of thermal ions and electrons are carried out for the ADITYA-U tokamak geometry using its experimental plasma profiles and with collisional effects. The dominant instability is trapped electron mode (TEM) based on the linear eigenmode structure and its propagation in the electron diamagnetic direction. Collisional effects suppress turbulence and transport to a certain extent. Zonal flow is not playing a critical role in the TEM saturation, which is dominated by the inverse cascade. The frequency spectrum of the electrostatic fluctuations is in broad agreement with the experimentally recorded spectrum in the ADITYA-U, with a bandwidth ranging from <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" overflow="scroll"> <mml:mrow> <mml:mo>∼</mml:mo> </mml:mrow> <mml:mn>0</mml:mn> </mml:math> to 50 kHz.
Simplified Adhesive Strength Measurement of Adhesive Protein in Marine Mussel (2006)

The adhesive protein of the mussel widely living in the ocean is expected as an ingredient of the adhesive. Adhesive strength of the protein to substratum has not been clarified because a method of measuring the strength does not exist. In this research, the plaque consisted of adhesive protein was peeled using the spatula-shaped jig inclined at the angle of 45 degrees to substratum. Adhesive strength was determined from the peeling load obtained by the jig with a strain gauge. To investigate the effect of the thickness of the plaque on the peeling load, based on linear fracture mechanics, peeling simulations of plaque from substratum were conducted using the finite element method. The simulation suggested that adhesive strength of the plaque to substratum is quantitatively evaluated by averaging the peeling load fluctuations.
Sandwiched‐fusion strategy facilitates recombinant production of small labile proteins (2021)

Efficient production of large quantities of soluble, properly folded proteins is of high demand in modern structural and functional genomics. Despite much advancement toward improving recombinant protein expression, many eukaryotic proteins especially small peptides often fail to be recovered due to rapid proteolytic degradation. Here we show that the sandwiched-fusion strategy, which is based on two protein tags incorporated both at the amino- and carboxyl-terminus of target protein, could be employed to overcome this obstacle. We have exploited this strategy on heterologous expression in Escherichia coli of eight small degradation-prone eukaryotic proteins, whose successful recombinant productions have yet to be achieved. These include seven mitochondria-derived peptides (MDPS), a class of unique metabolic regulators of human body, and a labile mosquito transcription factor, Guy1. We show here that the sandwiched-fusion strategy, which provides robust protection against proteolysis, affords an economical method to obtain large quantities of pure five MDPs and the transcription factor Guy1, in sharp contrast to otherwise unsuccessful recovery using the traditional amino-fusion method. Further biophysical characterization and interaction studies by NMR spectroscopy confirmed that the proteins produced by this novel approach are properly folded into their biologically active structures. We anticipate this strategy could be widely utilized in production of other labile protein systems.
A novel approach towards hydrazine sensor development using SrO·CNT nanocomposites (2016)

Strontium oxide nanoparticle decorated carbon nanotube nanocomposites (SrO·CNT NCs) were prepared in alkaline medium using a wet-chemical technique at low temperature.
Nanofluidics through a 30-nm aperture nanopipette by applying electrostatic field based on the QTF-AFM system (2010)

Nanofluidics of the liquid solution through a 30-nm aperture nanopipette was investgated using the QTF-AFM system. Used pulled nanopipette was attached on the edge of QTF to control the distance between the tip and substrate. Monitored QTF signal was changed by naturally formed water meniscus's force as tip approached to the sample within 10nm. After forming of water, electric field was applied for the purpose of a filled solution's extrusion onto the surface. Measured the fluid speed was 43.5 um/s and spread area was 136.6 um <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> after 5 seconds. During the experiment, temperature was 22 °C and humidity was 20.1 %. Checked thermal drift was 0.3 pm/s.