gebhart/patrepeval huggingface dataset:
Phthalocyanine compounds (1964)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhthalocyanine compoundsFrank H. Moser and Arthur L. Thomas Cite this: J. Chem. Educ. 1964, 41, 5, 245Publication Date (Print):May 1, 1964Publication History Received3 August 2009Published online1 May 1964Published inissue 1 May 1964https://doi.org/10.1021/ed041p245RIGHTS & PERMISSIONSArticle Views2172Altmetric-Citations25LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (4 MB) Get e-Alerts Get e-Alerts
Objective Function Zero for the Routing Protocol for Low-Power and Lossy Networks (RPL) (2012)

The Routing Protocol for Low-Power and Lossy Networks (RPL)
specification defines a generic Distance Vector protocol that is
adapted to a variety of network types by the application of specific
Objective Functions (OFs). An OF states the outcome of the process
used by a RPL node to select and optimize routes within a RPL Instance
based on the Information Objects available; an OF is not an algorithm.
This document specifies a basic Objective Function that relies only on
the objects that are defined in the RPL and does not use any protocol
extensions. [STANDARDS-TRACK]
Optimizing the CEBAF Injector for Beam Operation with a Higher Voltage Electron Gun (2011)

Recent developments in the DC gun technology used at CEBAF have allowed an increase in operational voltage from 100kV to 130kV. In the near future this will be extended further to 200kV with the purchase of a new power supply. The injector components and layout at this time have been designed specifically for 100kV operation. It is anticipated that with an increase in gun voltage and optimization of the layout and components for 200kV operation, that the electron bunch length and beam brightness can be improved upon. This paper explores some upgrade possibilities for a 200kV gun CEBAF injector through beam dynamic simulations.
An uncultured marine cyanophage encodes an active phycobilisome proteolysis adaptor protein NblA (2019)

Phycobilisomes (PBS) are large water-soluble membrane-associated complexes in cyanobacteria and some chloroplasts that serve as light-harvesting antennae for the photosynthetic apparatus. When deplete of nitrogen or sulphur, cyanobacteria readily degrade their phycobilisomes allowing the cell to replenish these vanishing nutrients. The key regulator in the degradation process is NblA, a small protein (∼6 kDa), which recruits proteases to the PBS. It was discovered previously that not only do cyanobacteria possess nblA genes but also that they are encoded by genomes of some freshwater cyanophages. A recent study, using assemblies from oceanic metagenomes, revealed genomes of a novel uncultured marine cyanophage lineage, representatives of which contain genes coding for the PBS degradation protein. Here, we examined the functionality of nblA-like genes from these marine cyanophages by testing them in a freshwater model cyanobacterial nblA knockout. One of the viral NblA variants could complement the non-bleaching phenotype and restore PBS degradation. Our findings reveal a functional NblA from a novel marine cyanophage lineage. Furthermore, we shed new light on the distribution of nblA genes in cyanobacteria and cyanophages.
Enantioselective Human Serum Albumin Binding of Apremilast: Liquid Chromatographic, Fluorescence and Molecular Docking Study (2023)

The interaction between human serum albumin (HSA) and apremilast (APR), a novel antipsoriatic drug, was characterized by multimodal analytical techniques including high-performance liquid chromatography (HPLC), fluorescence spectroscopy and molecular docking for the first time. Using an HSA chiral stationary phase, the APR enantiomers were well separated, indicating enantioselective binding between the protein and the analytes. The influence of chromatographic parameters-type and concentration of the organic modifier, buffer type, pH, ionic strength of the mobile phase, flow rate and column temperature-on the chromatographic responses (retention factor and selectivity) was analyzed in detail. The results revealed that the eutomer <i>S</i>-APR bound to the protein to a greater extent than the antipode. The classical van 't Hoff method was applied for thermodynamic analysis, which indicated that the enantioseparation was enthalpy-controlled. The stability constants of the protein-enantiomer complexes, determined by fluorescence spectroscopy, were in accordance with the elution order observed in HPLC (<i>K<sub>R</sub></i><sub>-APR-HSA</sub> = 6.45 × 10<sup>3</sup> M<sup>-1</sup>, <i>K<sub>S</sub></i><sub>-APR-HSA</sub> = 1.04 × 10<sup>4</sup> M<sup>-1</sup>), showing that, indeed, the later-eluting <i>S</i>-APR displayed a stronger binding with HSA. Molecular docking was applied to study and analyze the interactions between HSA and the APR enantiomers at the atomic level. It was revealed that the most favored APR binding occurred at the border between domains I and II of HSA, and secondary interactions were responsible for the different binding strengths of the enantiomers.
Classifying color edges in video into shadow-geometry, highlight, or material transitions (2003)

We aim at using color information to classify the physical nature of edges in video. To achieve physics-based edge classification, we first propose a novel approach to color edge detection by automatic noise-adaptive thresholding derived from sensor noise analysis. Then, we present a taxonomy on color edge types. As a result, a parameter-free edge classifier is obtained labeling color transitions into one of the following types: 1) shadow-geometry, 2) highlight edges, and 3) material edges. The proposed method is empirically verified on images showing complex real world scenes.
Development of Portable Astral Light using the High Power 3-Color LEDs (2011)

We was designed the portable LED light which can shadowless shooting and developed using a high-power LED that medical attention as a new lighting components for structural confirmation of oral dental area, medical and surgical lesions in the local area. LED which applied to the development, was used the 3-color LEDs for possible of implement a variety of colors and adjusted the light intensity. It is being magnified of delicacy expressiveness and three-dimensional for tone of the subject-specific. It has been developed a highly efficient light module that LED is used to consider the electrical characteristics and optical properties. SMPS has We was designed the portable LED light which can shadowless shooting and developed using a high-power LED that medical attention as a new lighting components for structural confirmation of oral dental area, medical and surgical lesions in the local area. LED which applied to the development, was used the 3-color LEDs for possible of implement a variety of colors and adjusted the light intensity. It is being magnified of delicacy expressiveness and three-dimensional for tone of the subject-specific. It has been developed a highly efficient light module that LED is used to consider the electrical characteristics and optical properties. SMPS has produced for use in mobile that can be driven at low voltage. In addition, it was also possible to implement a variety of colors from monochromatic Light to polychromatic light using by PWM control method and were available 32,768.
Three-dimensional modes of unsteady solid-flame combustion (2003)

Mathematical simulation is being widely used in modeling wave propagation in various physical, chemical, and biological processes, such as gasless combustion, frontal polymerization, etc. Numerical simulation is especially important in three-dimensional (3D) modeling of the spinning and chaotic waves propagating in nontransparent solids. In this paper, we analyze the system of equations that describes the propagation of a self-sustained wave through a cylindrical sample of combustible mixture. In this case, sample composition, sample radius, and heat loss from the sample surface will be used as variable parameters. We will describe (i) the combustion modes that give rise to periodic screw motion of one or several hot spots, (ii) inner wave structure, (iii) effect of parameters on the wave structure, (iv) some modes that have not yet been observed experimentally, (v) a loss of periodicity that leads to chaotic propagation of a 3D self-sustained wave.
Definitive XSL-FO (2003)

Foreword. Preface. Acknowledgements. 1. Introducing XSL-FO. 2. XSL-FO in context. The XML Family of Recommendations. Examples. 3. Basic Concepts. Formatting and Rendering. Processing Model. Formatting Object XML Vocabulary. 4. Areas and Pages. Area Model Details. Block and Inline Basics. Container Basics. Page Definition and Sequencing. 5. Generic Body Constructs. Lists. Graphics and Foreign Objects. Links. Leaders. 6. Tables. Tabular Structure. Tabular Appearance. 7. Static Content and Page Geometry Ssequencing. Page Regions, Headers, and Footers. Content Definition 199. Page Sequence Master Interleave (PSMI). Page Geometry Sequencing. 8. Floats and Footnotes. Floats. Footnotes. 9. Breaks, Borders, and Backgrounds. Breaks. Widows and Orphans. Keeps. Spacing, Conditionality, and Precedence. Borders. Backgrounds. 10. Interactive Objects. Reflecting Formatting Object State by Appearance. Interactively Changing the Effective Flow. 11. Supplemental Objects. Specialty Formatting Objects. The Importance of Bidirectional Text. The Mechanics of Mixing Text of Different Writing Directions. The Bidirectional Support Challenge. The Bidi-Override Object. The Character Object. The Color-Profile Object. The Declarations Object. Appendix A. Using XSLT with XSL-FO. XSLT Language Features Supporting XSL-FO. XSL-FO Language Features Similar to XSLT and Xpath. Appendix B. Expressions. Production Summary. XSL-FO Functions. Appendix C. Objects. Objects Summarized by Name. Objects Summarized by Type. Appendix D. Properties. Common Properties. Data Types. Inheritance and Shorthands. Property Summary. Appendix E. Choosing XSL-FO Products. Index.
Technical consideration for a new X‐ray video progressive scanning system for cardiac catheterization (1988)

The widespread growth of interventional angiographic procedures has expanded the use of X-ray video systems. Reduced radiation exposure to the patient and staff has been recently reported by implementing a new pulsed progressive scanning video system. We have shown that this system, which enables the pulsing of the X-ray generator at 30 pulses per second, results in a 50% reduction in radiation exposure. The technical parameters and implementation of a progressive scanning video system are discussed. Image quality, temporal and spatial resolution, and signal-to-noise ratio (SNR) were assessed using conventional interlaced and progressive video scanning. These comparisons documented improved resolution, no degradation of ejection fraction measurements, improved clinical images, and a 1.0-dB improvement in the SNR with the progressive scanning. Progressive scanning video systems reduce radiation exposure and provide an objective improvement in image quality over conventional scanning video systems.
Parenteral Nutrition Inhibits Tumor Necrosis Factor- α -Mediated IgA Response to Injury (2008)

Tumor necrosis factor-alpha is involved in the respiratory IgA immune response to injury. Both TNF-alpha blockade and PN impair this innate response, and blockade of IL-1beta impairs it to a degree. We hypothesize that these cytokines blunt this response via their known effects on the polymeric immunoglobulin receptor (pIgR), whereas the PN-induced deficit likely is multifactorial.
High-quality-factor Si₃N₄ microresonators towards integrated nonlinear and quantum light sources (2021)

991012980422503412 HKUST Electronic Theses High-quality-factor Si₃N₄ microresonators towards integrated nonlinear and quantum light sources by Wu Kaiyi thesis 2021 1 online resource (xxxi, 207 pages) : illustrations (some color) Photonic integrated circuit (PIC) is an excellent platform for nonlinear frequency…Read more ›
Revision Total Knee Arthroplasty for the Management of Periprosthetic Fractures (2017)

Periprosthetic fractures after total knee arthroplasty (TKA) can present reconstructive challenges. Not only is the procedure technically complex, but patients with these fractures may have multiple comorbidities, making them prone to postoperative complications. Early mobilization is particularly beneficial in patients with multiple comorbidities. Certain patient factors and fracture types may make revision TKA the ideal management option. Periprosthetic fractures around the knee implant occur most frequently in the distal femur, followed by the tibia and the patella. Risk factors typically are grouped into patient factors (eg, osteoporosis, obesity) and surgical factors (eg, anterior notching, implant malposition). Surgical options for periprosthetic fractures that involve the distal femur or proximal tibia include reconstruction of the bone stock with augments or metal cones or replacement with an endoprosthesis.
NADPH Oxidase Activation in Pancreatic Cancer Cells Is Mediated through Akt-dependent Up-regulation of p22 (2010)

We recently showed that Nox4 NADPH oxidase is highly expressed in pancreatic ductal adenocarcinoma and that it is activated by growth factors and plays a pro-survival, anti-apoptotic role. Here we investigate the mechanisms through which insulin-like growth factor I and serum (FBS) activate NADPH oxidase in pancreatic cancer (PaCa) cells. We show that in PaCa cells, NADPH oxidase is composed of Nox4 and p22(phox) catalytic subunits, which are both required for NADPH oxidase activity. Insulin-like growth factor I and FBS activate NADPH oxidase through transcriptional up-regulation of p22(phox). This involves activation of the transcription factor NF-κB mediated by Akt kinase. Up-regulation of p22(phox) by the growth factors results in increased Nox4-p22(phox) complex formation and activation of NADPH oxidase. This mechanism is different from that for receptor-induced activation of phagocytic NADPH oxidase, which is mediated by phosphorylation of its regulatory subunits. Up-regulation of p22(phox) represents a novel pro-survival mechanism through which growth factors and Akt inhibit apoptosis in PaCa cells.
EVHA: Explainable Vision System for Hardware Testing and Assurance—An Overview (2023)

Due to the ever-growing demands for electronic chips in different sectors, semiconductor companies have been mandated to offshore their manufacturing processes. This unwanted matter has made security and trustworthiness of their fabricated chips concerning and has caused the creation of hardware attacks. In this condition, different entities in the semiconductor supply chain can act maliciously and execute an attack on the design computing layers, from devices to systems. Our attack is a hardware Trojan that is inserted during mask generation/fabrication in an untrusted foundry. The Trojan leaves a footprint in the fabrication through addition, deletion, or change of design cells. To tackle this problem, we propose EVHA (Explainable Vision System for Hardware Testing and Assurance) in this work, which can detect the smallest possible change to a design in a low-cost, accurate, and fast manner. The inputs to this system are scanning electron microscopy images acquired from the integrated circuits under examination. The system output is the determination of integrated circuit status in terms of having any defect and/or hardware Trojan through addition, deletion, or change in the design cells at the cell level. This article provides an overview on the design, development, implementation, and analysis of our defense system.
Solar energy processor based on Packed U-Cells 7-level inverter for grid applications (2016)

This paper presents a solar energy processor based on Packed U-Cells inverter for grid applications. The proposed single phase multilevel inverter PUC allows the generation of 7-level output voltage. Two control techniques are used in this work. MPPT is applied on the PV in order to extract the maximum power, while the aim of MPC or the model predictive control is to balance three variables in the system; the grid current, the capacitor voltage in the PUC as well as the BOOST output voltage. The feasibility of the designed system is validated by simulation using Matlab-Simulink-SimPowerSystems.
Three-way flexible cantilever probes for static contact (2011)

In micro four-point probe measurements, three-way flexible L-shaped cantilever probes show significant advantages over conventional straight cantilever probes. The L-shaped cantilever allows static contact to the sample surface which reduces the frictional wear of the cantilever tips. We analyze the geometrical design space that must be fulfilled for the cantilevers to obtain static contact with the test sample. The design space relates the spring constant tensor of the cantilevers to the minimal value of the static tip-to-sample friction coefficient. Using an approximate model, we provide the analytical calculation of the compliance matrix of the L-shaped cantilever. Compared to results derived from finite element model simulations, the theoretical model provides a good qualitative analysis while deviations for the absolute values are seen. From a statistical analysis, the deviation is small for cantilevers with low effective spring constants, while the deviation is significant for large spring constants where the quasi one-dimensional approximation is no longer valid.
The concept of stimulation of entrepreneurship— A benchmarking and co‐evolution approach (2004)

Abstract Sustainable economic growth is enabled by the production of wealth, i.e., development of entrepreneurship. Opportunities for its development, and so the sources of the country's economic wealth, may be found today not only in the proper level of macroeconomic indicators (labor cost, interest rates' level, currency exchange rate, etc.), but also in regional (effective and efficient use of locally diverse opportunities, development predisposition, and cooperation between organizations) and microeconomic conditions (differences in management styles). The sine qua non condition of the entrepreneurship development is the effectiveness of actions taken in all three interrelated levels enabling achievement of the synergy effect. Our aim here is to present an innovative concept of entrepreneurship, realized in Poland on the basis of the cooperation between science, business, authorities, institutions, and media. © 2005 Wiley Periodicals, Inc. Hum Factors Man 15: 71–82, 2005.
Abstract B157: OX40 expression in tumor-associated Tregs as a potential prognostic biomarker and immunotherapeutic target in ovarian cancer (2016)

Abstract Background - Treatment of ovarian cancer remains very challenging, with 80-85% of the cases still dying after relapse to standard chemotherapy, and alternative treatments are urgently needed. Expansion of regulatory T cells (Tregs) is considered the major factor limiting spontaneous immune responses to ovarian cancer. Agonist antibodies against the co-stimulatory receptor OX40 have recently demonstrated to abrogate Treg functions and are under clinical evaluation. We thus studied whether OX40 constituted a valid target of ovarian cancer-associated Tregs. Methods -Treg immunophenotypic analyses were performed by flow cytometry in ascites and ovarian cancer specimens and studied in association with patients' outcome. Results - CD4+CD25+Foxp3+ Treg% and OX40 expression were measured in 50 diagnostic ovarian cancer cases (36, high grade serous carcinomas; 14, other histotypes). Treg% was significantly higher in ovary (47 evaluable cases) relative to ascites (39 evaluable cases) (p&amp;lt;0.0001). Treg % in ascites and peripheral blood from ovarian cancer patients or healthy donors were not significantly different. The fraction of Tregs expressing OX40, instead, dramatically increased from peripheral blood to ascites (p&amp;lt;0.01), and was even higher within the tumor (p&amp;lt;0.001). In 24 patients (stage IIC-IV; 19, high grade serous carcinoma; 5, other histotypes) with ≥12-month follow-up after surgery and carboplatin-paclitaxel, we analyzed OX40 expression on intratumor Tregs in function of the outcome. Patients with Treg% or OX40 MFI above the mean had a significantly reduced OS (p=0.004, p=0.02). Interestingly, having both high Treg% and OX40 MFI trended toward the worst OS, followed by high Treg% or OX40 MFI alone, whereas the lack of these parameters was associated with a significantly improved survival (mean: 28, 36, 41 and 53 months). OX40+ Tregs in both ascites and ovarian cancer tissue included CD45RA-, Foxp3hi, ICOS+ IFNγ- effector Tregs, thus indicating that OX40 may define a subset of highly suppressive Tregs in ovarian cancer. Conclusions - Our study underscores a negative prognostic impact of OX40 expression on ovarian cancer-infiltrating Tregs and indicates that OX40 may constitute a rational target to counteract effector Treg functions and unleash potentially effective immune responses against ovarian cancer. Citation Format: Massimo Di Nicola, Roberta Zappasodi, Alessia Burocci, Giusi Ruggiero, Fabio Martinelli, Claudio Tripodo, Domenica Lorusso, Filippo De Braud, Francesco Raspagliesi, Mario P. Colombo. OX40 expression in tumor-associated Tregs as a potential prognostic biomarker and immunotherapeutic target in ovarian cancer. [abstract]. In: Proceedings of the CRI-CIMT-EATI-AACR Inaugural International Cancer Immunotherapy Conference: Translating Science into Survival; September 16-19, 2015; New York, NY. Philadelphia (PA): AACR; Cancer Immunol Res 2016;4(1 Suppl):Abstract nr B157.
Computer Simulation Techniques in Giant Cell Tumor Curettage and Defect Reconstruction (2012)

Giant cell tumors (GCT) are often treated with curettage followed by defect reconstruction. In this study, curettage of a femoral GCT was simulated on a patient-specific computer model, and the defective femur was converted to a plastic prototype to guide onsite GCT curettage. Three reconstruction methods were simulated to achieve an optimal surgical plan.
Agglomeration Economies in China: Locations and Effects (2014)

The nature and location of urbanization economies and their effects on productivity per worker in China are examined. Unlike previous studies, more accurate resident-based measures of urban scale from the 2010 census are used. The size of urbanization economies is similar to those in other countries and they occur only in bigger cities and not in smaller towns, and operate only through tertiary sector activity. Efforts by government to disperse urbanization, through land use and migration restrictions and by stimulating construction and manufacturing in China’s counties, are unlikely to create beneficial agglomeration effects.
Submicron pattern transfer to binary semiconductors via micromolding in capillaries (2002)

We report on the high-resolution patterning of III–V semiconductors through polymeric masks by a soft lithographic technique based on micromolding in capillaries. The basic study of the capillarity process and the optimization of the technological steps allowed us to transfer patterns on both GaAs and InP with resolution of 800 nm over areas up to 1 cm2 and of a few microns over areas up to 4 cm2.