MP71-09 A PROSPECTIVE AND RANDOMIZED TRIAL COMPARING TRANSURETHRAL RESECTION OF THE PROSTATE (TURP) TO PROSTATE ARTERY EMBOLIZATION (PAE) FOR TREATMENT OF BLADDER OUTLET OBSTRUCTION DUE TO BENIGN PROSTATIC HYPERPLASIA (BPH) (2014)

You have accessJournal of UrologyBenign Prostatic Hyperplasia: Surgical Therapy & New Technology II1 Apr 2014MP71-09 A PROSPECTIVE AND RANDOMIZED TRIAL COMPARING TRANSURETHRAL RESECTION OF THE PROSTATE (TURP) TO PROSTATE ARTERY EMBOLIZATION (PAE) FOR TREATMENT OF BLADDER OUTLET OBSTRUCTION DUE TO BENIGN PROSTATIC HYPERPLASIA (BPH) Eduardo Muracca Yoshinaga, Elcio Nakano, Giovanni S. Marchini, Octavio Galvao, Ronaldo Baroni, Francisco C. Carnevale, Giovanni G. Cerri, Miguel Srougi, and Alberto A. Antunes Eduardo Muracca YoshinagaEduardo Muracca Yoshinaga , Elcio NakanoElcio Nakano , Giovanni S. MarchiniGiovanni S. Marchini , Octavio GalvaoOctavio Galvao , Ronaldo BaroniRonaldo Baroni , Francisco C. CarnevaleFrancisco C. Carnevale , Giovanni G. CerriGiovanni G. Cerri , Miguel SrougiMiguel Srougi , and Alberto A. AntunesAlberto A. Antunes View All Author Informationhttps://doi.org/10.1016/j.juro.2014.02.2168AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES PAE has been proposed an an alternative option for treatment of benign prostatic hyperplasia (BPH). The purpose of our investigation is to compare clinical and urodynamic results of PAE and TURP for treatment of symptomatic BPH. METHODS After IRB approval, we prospectively randomized patients to receive either TURP or PAE for BPH treatment. Inclusion criteria comprised: men >50 years old; International Prostate Symptoms Score (IPSS) >19 refractory to medical treatment; negative screening for prostate cancer; prostate volume between 30-90g on magnetic resonance image (MRI); and bladder outlet obstruction confirmed by urodynamic examination. Patients with renal failure, bladder calculi or diverticulum, or urethral stenosis were excluded. We analyzed urodynamic parameters (urinary flow, bladder outlet obstruction index - BOOI), prostate volume, IPSS and Disease Specific Quality of Life Question Index (QOL). Minimum follow-up considered was 1 year. Paired T test was used to compare pre and 1 year post-intervention parameters in each group. Groups were compared with Student T test or Chi-square/Fisher exact test. The level of significance was set at p¡Ü0.05. RESULTS 30 patients were randomized. Mean follow-up was 18 months. Groups were comparable for all preoperative parameters (table 1). Both cohorts had a significant improvement in mean urinary flow, BOOI, IPSS and QOL (table 1). No complications were observed in any group; 2 patients from PAE required TURP due to maintained obstructive symptoms after 6 and 12 months. TURP provided a higher postoperative urinary flow with more pronounced improvement in BOOI, IPSS and QOL scores (p<0.001). PSA levels and IEF were similar postoperatively between cohorts. CONCLUSIONS PAE and TURP are safe and effective for BPH treatment. However TURP provides a more significant relief of obstruction. These results suggest that PAE should be indicated to patients with a mild or moderate grade of obstruction only. © 2014FiguresReferencesRelatedDetails Volume 191Issue 4SApril 2014Page: e793 Advertisement Copyright & Permissions© 2014MetricsAuthor Information Eduardo Muracca Yoshinaga More articles by this author Elcio Nakano More articles by this author Giovanni S. Marchini More articles by this author Octavio Galvao More articles by this author Ronaldo Baroni More articles by this author Francisco C. Carnevale More articles by this author Giovanni G. Cerri More articles by this author Miguel Srougi More articles by this author Alberto A. Antunes More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...