gebhart/patrepeval huggingface dataset:
Enhanced Power within a Specific Band of Theta Activity in One Person While Another Receives Circumcerebral Pulsed Magnetic Fields: A Mechanism for Cognitive Influence at a Distance? (2003)

Four pairs of adult siblings served once as either the stimulus or the response person in two sessions separated by one week. While the brain of the stimulus person, who was seated in a closed chamber, was exposed successively to six different complex magnetic fields for 5 min. each quantitative monopolar electroencephalographic measurements over the frontal, temporal, parietal, and occipital lobes were collected by computer for the response person who was seated in another room. The six configurations of fields served as different stimulus patterns and had been designed to affect consciousness. As predicted theoretically, a significant increase in electroencephalographic power within the 5.0-Hz to 6.0-Hz band over the frontal and occipital lobes was noted for the response persons when the stimulus persons received one of the six specific patterns of weak (1 microTesla range) magnetic fields. This magnetic stimulus was presented for 100 msec. with changes in rate of 20 msec. to each of the eight solenoids that were equally spaced in the horizontal plane around the head of the stimulus person. Derivatives within this narrow frequency band had been hypothesized to be a source of the "binding factor" for the cohesive cerebrogenic electromagnetic fields producing consciousness. The results suggest that an appropriate altered state of one brain can effect specific predictable frequencies of the electroncephalographic activity of another distant brain which is genetically related.
"Multifunctional Ionic Liquid-Fe3O4 Core/Chitosan Shell Magnetic Hydrogel for Magnetic Responsive, pH-triggered and Long-Acting Hormone Therapy" (2016)

biotechnology open access journals Advances in biotechnology and microbiology is an Open Access, peer reviewed scientific journal focused towards publishing a complete and reliable source of information on the innovations and ongoing developments in the field of Biotechnology & Microbiology.
Epicardial mapping of ventricular defibrillation with monophasic and biphasic shocks in dogs. (1993)

To study the mechanism of defibrillation and the reason for the increased defibrillation efficacy of biphasic waveforms, the potential gradient in a 32 x 30-mm region of the right ventricle in 15 dogs was progressively lowered in four steps while a strong potential gradient field was maintained throughout the rest of the ventricular myocardium. The volume of right ventricle beneath the plaque was 10 +/- 2% of the total ventricular mass. A 10-msec monophasic (eight dogs) or 5/5-msec biphasic (seven dogs) truncated exponential shock 30% above the defibrillation threshold voltage was given via electrodes on the left ventricular apex and right atrium to create the strong potential gradient field. Simultaneously, a weaker shock with the same waveform but opposite polarity was given via mesh electrodes on either side of the small right ventricular region to cancel part of the potential difference in the region and to create one of the four levels of potential gradient fields. Shock potentials and activations were recorded from 117 epicardial electrodes in the small region, and in one dog global epicardial activations and potentials were recorded from a sock containing 72 electrodes. Each gradient field was tested 10 times for successful defibrillation after 10 seconds of electrically induced fibrillation. For both monophasic and biphasic shocks, the percentage of successful defibrillation attempts decreased (p < 0.05) as the potential gradient decreased in the small region. Defibrillation was successful approximately 80% of the time for a mean +/- SD potential gradient of 5.4 +/- 0.8 V/cm for monophasic shocks and 2.7 +/- 0.3 V/cm for biphasic shocks (p < 0.05). No postshock activation fronts arose from the small region for eight waveform when the gradient was more than 5 V/cm. For both waveforms, the postshock activation fronts after the shocks were markedly different from those just before the shock and exhibited either a focal origin or unidirectional conduction.(ABSTRACT TRUNCATED AT 400 WORDS)
On ordered normally distributed vector parameter estimates (2015)

The ordered values of a sample of observations are called the order statistics of the sample and are among the most important functions of a set of random variables in probability and statistics. However the study of ordered estimates seems to have been overlooked in maximum-likelihood estimation. Therefore it is the aim of this communication to give an insight into the relevance of order statistics in maximum-likelihood estimation by providing a second-order statistical prediction of ordered normally distributed estimates. Indeed, this second-order statistical prediction allows to refine the asymptotic performance analysis of the mean square error (MSE) of maximum likelihood estimators (MLEs) of a subset of the parameters. A closer look to the bivariate case highlights the possible impact of estimates ordering on MSE, impact which is not negligible in (very) high resolution scenarios.
ChemInform Abstract: SPALTUNG DER C‐N‐BINDUNG IM N,N,N′,N′‐TETRAKIS‐(2‐VINYLOXY‐AETHYL)‐METHYLENDIAMIN (1972)

Abstract Das Methylendiamin (I) reagiert mit den Bromiden (II) als Nukleophilen (analog auch mit Acetanhydrid) unter Spaltung der C‐N‐Bindung zu den Aminen (III) (Ausbeute 50‐99%); die Reaktionsprodukte fallen teilweise in Form von Polymeren an.
Novel engineered TRAIL‐based chimeric protein strongly inhibits tumor growth and bypasses TRAIL resistance (2019)

Targeting of the TRAIL-DR4/5 pathway was proposed as a promising approach for specific induction of apoptosis in cancer cells. Clinical trials, however, showed inadequate efficiency of TRAIL as a monotherapy. It is a widely held view that the application of multifunctional molecules or combination therapy may lead to substantial improvement. Here, we demonstrate the effectiveness and safety of a novel chimeric protein, AD-O51.4, which is a TRAIL equipped with positively charged VEGFA-derived effector peptides. The study was performed in multiple cancer cell line- and patient-derived xenografts. A pharmacokinetic profile was established in monkeys. AD-O51.4 strongly inhibits tumor growth, even leading to complete long-term tumor remission. Neither mice nor monkeys treated with AD-O51.4 demonstrate symptoms of drug toxicity. AD-O51.4 exhibits a satisfactory half-life in plasma and accumulates preferentially in tumors. The cellular mechanism of AD-O51.4 activity involves both cytotoxic effects in tumor cells and antiangiogenic effects on the endothelium. The presence of DRs in cancer cells is crucial for AD-O51.4-driven apoptosis execution. The TRAIL component of the fusion molecule serves as an apoptosis inducer and a cellular anchor for the effector peptides in TRAIL-sensitive and TRAIL-resistant cancer cells, respectively. The FADD-dependent pathway, however, seems to be not indispensable in death signal transduction; thus, AD-O51.4 is capable of bypassing the refractoriness of TRAIL. AD-O51.4-driven cell death, which exceeds TRAIL activity, is achieved due to the N-terminally fused polypeptide, containing VEGFA-derived effector peptides. The high anticancer efficiency of AD-O51.4 combined with its safety has led to the entry of AD-O51.4 into toxicological studies.
P‐80: External Electrode Fluorescent Lamps and Backlight Units for the Large Area of 32″∼42″ LCD‐TVs (2007)

Abstract The commercialized EEFL‐BLUs of 32″, 37″, and 42″ LCD‐TVs are reported with respect to the basic characteristics of luminance and efficiency. The capacitive and resistive reactance is also presented to design the inverter for lamps and BLUs.
Frequency Agile Diode Laser-Pumped Tm,Ho:YLiF4 Local Oscillator with 3.6 GHz Tuning Range (1995)

Eyesafe solid-state laser technology based on the holmium 5 I 7 - 5 I 8 transition is being vigorously developed by NASA in a focussed program directed towards their ultimate use in atmospheric and planetary remote sensing from orbital platforms. Specifically thulium and holmium sensitized yttrium lithium fluoride (Tm,Ho:YLiF 4 ) lasers have benefitted from much recent effort in which improvements in efficiency, Q-switched operation and single frequency oscillation have been demonstrated (1,2,3) .
Dead space ventilation promotes alveolar hypocapnia reducing surfactant secretion by altering mitochondrial function (2019)

Accordingly, we provide evidence that alveolar hypocapnia leads to a Ca<sup>2+</sup> shift from the cytosol into mitochondria. The subsequent decline of [Ca<sup>2+</sup>]<sub>cyt</sub> reduces surfactant secretion and thus regional ventilation in lung regions with high V<sub>D</sub>/V<sub>T</sub>. Additionally, the regional hypoventilation provoked by perfusion failure can be inhibited by inspiratory CO<sub>2</sub> application.
Cooperating constructions in Lai "lexical insertion" (2003)

In this paper we investigate the factors conditioning a morphological alternation on verbal heads in Lai. We show that this alternation eludes a simple characterization and instead exhibits a many-to-many form-function mapping. We will further show that the facts can be given a straightforward analysis in terms of default conditions based on valence and polarity, together with various constructional overrides. Our analysis thus follows recent proposals in HPSG, in particular Malouf (forthcoming), in using a constructional type hierarchy with defaults (cooperating constructions) as an alternative to an Optimality Theoretic system of ranked violable constraints.
In Vivo MRI Versus Ex Vivo CT for Image-Based CFD of the Mouse Aorta (2012)

A novel mouse model of surgically induced aortic valve regurgitation (AR) has been developed which leads to altered hemodynamics in the descending thoracic and abdominal aorta, in turn leading to extensive atherosclerotic lesions in these otherwise lesion free areas [1]. Previous work has shown that maps of oscillatory shear index (OSI) and relative residence time (RRT) are consistent with the plaque distribution [2] and plaque severity in AR mice.
<p>Trastuzumab with FLOT Regimen for the Perioperative Treatment of Resectable HER2 + Advanced Gastric Cancer: A Retrospective Study</p> (2020)

Trastuzumab combined with FLOT has a good curative effect and safety profile in the perioperative treatment of patients with resectable HER-2-positive advanced gastric cancer. In addition, trastuzumab + FLOT had the same result as FLOT alone, as there was no significant benefit with the addition of T in the group studied.
Magnesium Nanoparticle Synthesis from Powders via Pulsed Laser Ablation in Liquid for Nanocolloid Production (2021)

Magnesium nanoparticles of various mean diameters (53–239 nm) were synthesised in this study via pulsed laser ablation in liquid (PLAL) from millimetre sized magnesium powders within isopropyl alcohol. It was observed via a 3 × 3 full factorial design of experiments that the processing parameters can control the nanoparticle distribution to produce three size-distribution types (bimodal, skewed and normal). Ablation times of 2, 5, and 25 min where investigated. An ablation time of 2 min produced a bimodal distribution with the other types seen at higher periods of processing. Mg nanoparticle Ultraviolet–Visible spectroscopy (UV–Vis) absorbance at 204 nm increased linearly with increasing ablation time, indicating an increase in nanoparticle count. The colloidal density (mg/mL) generally increased with increasing nanoparticle mean diameter as noted via increasing UV–Vis absorbance. High laser scan speeds (within the studied range of 3000–3500 mm/s) tend to increase the nanoparticle count/yield. For the first time, the effect of scan speed on colloidal density, UV–Vis absorbance and nanoparticle diameter from metallic powder ablation was investigated and is reported herein. The nanoparticles formed dendritic structures after being drop cast on aluminium foil as observed via field emission scanning electron microscope analysis. Dynamic light scattering was used to measure the size of the nanoparticles. Magnesium nanoparticle inks show promise for use in the fabrication conductive tracks or thermal insulation in electronics.
Autonomous environmental measurement system (1995)

For experiment planning and optimized array deployment, experiment planners and array designers often seek a quick, affordable means to help determine best placement of a underwater acoustic measurement system prior to deployment. Array design geometry relative to ambient noise levels and variability, seafloor morphology, currents, and water column structure (e.g., ducts) is aided by apriori knowledge of the setting. It is desirable to determine some of these unknowns before undertaking the time and effort of a system deployment. Likewise, experiment planners and array designers would like to be able to explore deployment schemes that are locally optimized for the environment in order to reduce sensor sparseness in critical areas. This presentation describes an expendable, inexpensive sensor suite installed approximately one week prior to the deployment of an underwater acoustic measurement system. The instrument collects environmental data and provides advanced information to the experiment planners prior to a final deployment, facilitating optimized placement of the measurement system. Parameters sampled include: Variability and average level of ambient noise, SVPs, seafloor type and sediment thickness, surface wave heights, tidal measurements, and water currents. Characteristics of the system described include its small size, low weight, low power, affordability, and simple, low-bandwidth data collection scheme based on slack line array technology. [Work supported by ONR, Code 321.]
Application of Subject Specific Models for Mapping Brain Function with Diffuse Optical Tomography (2010)

The application of diffuse optical tomography (DOT) methods for neuroimaging of humans is challenging due to the geometry of each individual subject and light level constraints. A high density imaging array system has been developed and used to demonstrate the possibility of true tomographic reconstruction of cortical activity within the adult subjects which are consistent with studies using functional MRI and positron-emission tomography. This work demonstrates the benefits of using subject specific models for image reconstruction and investigates depth related information available from the increased number of tomographic measurements.
Optical force sensor array in a microfluidic device based on holographic optical tweezers (2009)

Holographic optical tweezers (HOT) are a versatile technology, with which complex arrays and movements of optical traps can be realized to manipulate multiple microparticles in parallel and to measure the forces affecting them in the piconewton range. We report on the combination of HOT with a fluorescence microscope and a stop-flow, multi-channel microfluidic device. The integration of a high-speed camera into the setup allows for the calibration of all the traps simultaneously both using Boltzmann statistics or the power spectrum density of the particle diffusion within the optical traps. This setup permits complete spatial, chemical and visual control of the microenvironment applicable to probing chemo-mechanical properties of cellular or subcellular structures. As an example we constructed a biomimetic, quasi-two-dimensional actin network on an array of trapped polystyrene microspheres inside the microfluidic chamber. During crosslinking of the actin filaments by Mg(2+) ions, we observe the build up of mechanical tension throughout the actin network. Thus, we demonstrate how our integrated HOT-microfluidics platform can be used as a reconfigurable force sensor array with piconewton resolution to investigate chemo-mechanical processes.
Amacrine Cell Subtypes Differ in Their Intrinsic Neurite Growth Capacity (2013)

Our data suggest that cultured amacrine cells maintain intrinsic fidelity to their identified in vivo subtypes, and furthermore, that cell-autonomous, intrinsic factors contribute to the regulation of neurite patterning.
Functional vascular smooth muscle cells derived from human induced pluripotent stem cells via mesenchymal stem cell intermediates (2012)

We developed an efficient stage-wise strategy that enabled hiPSC differentiation into contractile SMC through an intermediate population of clonogenic and multipotent MSC. The high yield of MSC and SMC derivation suggests that our strategy may facilitate an acquisition of the large numbers of cells required for regenerative medicine or for studying vascular disease pathophysiology.
<title>Vectorial FDBPM 3D waveguide structures</title> (1994)

A fully vectorial finite difference beam propagation method for 3D waveguide structures, including longitudinally variant structures is presented. The transparent boundary conditions are utilized in the edges of the computational window. Both Gaussian beams and exact fields of the guided modes are launched as the starting field. Propagating fields are calculated and the power attenuation is evaluated. The choice of step size, finite difference scheme parameter and reference propagation constant is discussed. The applicability and accuracy are demonstrated for two particular waveguide structures.
Maximum entropy analysis of quasielastic light scattering from colloidal dispersions (1986)

The maximum entropy method (MEM) is used to analyze quasielastic light scattering correlation functions. The central problem, in such data analysis, is the recovery of the distribution of exponentials describing the decay of the correlation function (i.e., inverting the Laplace transform). MEM is shown to give a high-quality reconstruction of these distributions. The success of the method is illustrated with results from computer-generated ‘‘noisy’’ data and with experimental data from colloidal dispersions. Both the theoretical properties, and practical advantages of MEM are presented and compared with current data analysis techniques.
The Conundrum of Skin Pores in Dermocosmetology (2004)

'Skin pore' is a term used by lay people and in the field of cosmetology. It remains misleading when it is not clearly defined. Indeed, lay people use it with at least 3 different meanings. Basically, invisible pores represent the openings of the sweat gland apparatus. By contrast, the visible pores represent enlarged empty funnel-shaped or cylindrical horny impacted openings of pilosebaceous follicles. This review describes some of the current objective methods used to describe skin pores.
Dynamic ransomware protection using deterministic random bit generator (2017)

Ransomware has become a very significant cyber threat. The basic idea of ransomware was presented in the form of a cryptovirus in 1995. However, it was considered as merely a conceptual topic since then for over a decade. In 2017, ransomware has become a reality, with several famous cases of ransomware having compromised important computer systems worldwide. For example, the damage caused by CryptoLocker and WannaCry is huge, as well as global. They encrypt victims' files and require user's payment to decrypt them. Because they utilize public key cryptography, the key for recovery cannot be found in the footprint of the ransomware on the victim's system. Therefore, once infected, the system cannot be recovered without paying for restoration. Various methods to deal this threat have been developed by antivirus researchers and experts in network security. However, it is believed that cryptographic defense is infeasible because recovering a victim's files is computationally as difficult as breaking a public key cryptosystem. Quite recently, various approaches to protect the crypto-API of an OS from malicious codes have been proposed. Most ransomware generate encryption keys using the random number generation service provided by the victim's OS. Thus, if a user can control all random numbers generated by the system, then he/she can recover the random numbers used by the ransomware for the encryption key. In this paper, we propose a dynamic ransomware protection method that replaces the random number generator of the OS with a user-defined generator. As the proposed method causes the virus program to generate keys based on the output from the user-defined generator, it is possible to recover an infected file system by reproducing the keys the attacker used to perform the encryption.
Frequent Item Computation on a Chip (2010)

Computing frequent items is an important problem by itself and as a subroutine in several data mining algorithms. In this paper, we explore how to accelerate the computation of frequent items using field-programmable gate arrays (FPGAs) with a threefold goal: increase performance over existing solutions, reduce energy consumption over CPU-based systems, and explore the design space in detail as the constraints on FPGAs are very different from those of traditional software-based systems. We discuss three design alternatives, each one of them exploiting different FPGA features and each one providing different performance/scalability trade-offs. An important result of the paper is to demonstrate how the inherent massive parallelism of FPGAs can improve performance of existing algorithms but only after a fundamental redesign of the algorithms. Our experimental results show that, e.g., the pipelined solution we introduce can reach more than 100 million tuples per second of sustained throughput (four times the best available results to date) by making use of techniques that are not available to CPU-based solutions. Moreover, and unlike in software approaches, the high throughput is independent of the skew of the Zipf distribution of the input and at a far lower energy cost.
JTRS-an open, distributed-object computing software radio architecture (2003)

The Joint Tactical Radio System (JTRS) program is a 3-step process to define, standardize, and implement a software defined radio architecture. Step 1 resulted in a baseline architecture definition. In Step 2 the architecture definition will be developed and validated as the Software Communications Architecture (SCA) which will be the basis for future DoD software radios. The SCA is also expected to become the standard for Government and commercial software radios. Step 3 activities will result in procurement and integration of systems and waveforms that are compliant with the SCA and which satisfy individual DoD user requirements. During Step 3, the architecture will continue to evolve in response to new or changing warfighter requirements and technology advancements. The JTRS is defined in terms of its hardware, software, networking, and security architecture. This paper addresses the Software Communications Architecture.