gebhart/patrepeval huggingface dataset:
A clinical analysis of 230 children with hand-foot-mouth disease (2009)

Objective To summarize the experience of diagnosis and treatment of hand-foot-mouth disease in children.Methods A total of 230 children with hand-foot-mouth disease in the hospital from May 2008 to October 2008 were retrospectively analyzed in terms of epidemiology,clinical features,treatment and prognosis.Results Out of the 230 cases,172 were from nurseries and kindergartens.One hundred and sixty cases had the clear contact history.Typical signs and symptoms,including oral ulcerative herpes and blister-like rash in extremities,were found in all cases.All children were cured after timely diagnosis and early treatment with ribavirin.Conclusion Timely treatment based on early diagnosis,considerate care as well as relevant prophylaxis and isolation are essential for reducing the occurrence of the disease.
Quantitative molecular detection of minimal residual head and neck cancer in lymph node aspirates. (2003)

Real-time E48 Q-RT-PCR is an accurate technique for squamous cell detection in lymph node aspirates of HNSCC patients. The assay shows an increase in sensitivity and frequency of reached diagnosis compared with cytology. The test could be implemented routinely in USgFNAC to diagnose cases for which cytological examination is not conclusive.
Profiling Carbonylated Proteins in Human Plasma (2010)

This study reports the first proteomic-based identification and characterization of oxidized proteins in human plasma. The study was conducted by isolating carbonylated proteins from the plasma of male subjects (age 32-36) with avidin affinity chromatography subsequent to biotinylation of carbonyl groups with biotin hydrazide and sodium cyanoborohydride reduction of the resulting Schiff's bases. Avidin selected proteins were digested with trypsin, and the peptide fragments were separated by C18 reversed phase chromatography and identified and characterized by both electrospray ionization and matrix assisted laser desorption ionization mass spectrometry. Approximately 0.2% of the total protein in plasma was selected with this method. Sixty-five high, medium, and low abundance proteins were identified, the majority appearing in all subjects. An interesting feature of the oxidized proteins isolated was that in addition to carbonylation they often bore other types of oxidative modification. Twenty-four oxidative modifications were mapped in 14 proteins. Fifteen carbonylation sites carried on 7 proteins were detected. Methionine oxidation was the most frequent single type of oxidative modification followed by tryptophan oxidation. Apolipoprotein B-100 had 20 oxidative modifications, the largest number for any protein observed in this study. Among the organs contributing oxidized proteins to plasma, kidney, liver, and soft tissues were the most frequent donors. One of the more important outcomes of this work was that mass spectral analysis allowed differentiation between different biological mechanisms of oxidation in individual proteins. For the first time, oxidation products arising from direct ROS oxidation of amino acid side chains in proteins, formation of advanced glycation endproducts (AGEs) adducts, and formation of adducts with lipid peroxidation products were simultaneously recognized and assigned to specific sites in proteins.
Performance evaluation of 3D vision-based semi-autonomous control method for assistive robotic manipulator (2017)

We developed a 3D vision-based semi-autonomous control interface for assistive robotic manipulators. It was implemented based on one of the most popular commercially available assistive robotic manipulator combined with a low-cost depth-sensing camera mounted on the robot base. To perform a manipulation task with the 3D vision-based semi-autonomous control interface, a user starts operating with a manual control method available to him/her. When detecting objects within a set range, the control interface automatically stops the robot, and provides the user with possible manipulation options through audible text output, based on the detected object characteristics. Then, the system waits until the user states a voice command. Once the user command is given, the control interface drives the robot autonomously until the given command is completed. In the empirical evaluations conducted with human subjects from two different groups, it was shown that the semi-autonomous control can be used as an alternative control method to enable individuals with impaired motor control to more efficiently operate the robot arms by facilitating their fine motion control. The advantage of semi-autonomous control was not so obvious for the simple tasks. But, for the relatively complex real-life tasks, the 3D vision-based semi-autonomous control showed significantly faster performance. Implications for Rehabilitation A 3D vision-based semi-autonomous control interface will improve clinical practice by providing an alternative control method that is less demanding physically as well cognitively. A 3D vision-based semi-autonomous control provides the user with task specific intelligent semiautonomous manipulation assistances. A 3D vision-based semi-autonomous control gives the user the feeling that he or she is still in control at any moment. A 3D vision-based semi-autonomous control is compatible with different types of new and existing manual control methods for ARMs.
The monomeric glutamyl-tRNA synthetase of Escherichia coli. Purification and relation between its structural and catalytic properties. (1979)

The glutamyl-tRNA synthetase has been purified to homogeneity from Escherichia coli with a yield of about 50%. It is a monomer with a molecular weight of 56,000 and has the same kinetic properties as those of the alpha chain of the dimeric alphabeta-glutamyl-tRNA synthetase described previously (Lapointe, J., and Söll, D. (1972) J. Biol. Chem. 247, 4966-4974). It is the smallest amino-acyl-tRNA synthetase purified from E. coli and contains no important sequence repetition. It is also the only monomeric aminoacyl-tRNA synthetase reported so far to contain no major sequence duplication. Considering its structural and mechanistic similarities with the glutaminyl- and the arginyl-tRNA synthetases of E. coli, we propose the existence of a relation between the true monomeric character of the glutamyl-tRNA synthetase (as opposed to monomers with sequence duplications) and its requirement for tRNA in the activation of glutamate. A single sulfhydryl group of the native enzyme reacts with 5,5'-dithiobis(2-nitrobenzoic acid) causing no loss of enzymatic activity, whereas four such groups per enzyme react in the presence of 4 M guanidine HCl.
Efficient and Selective Carboligation with Whole‐Cell Biocatalysts in Pickering Emulsion (2019)

Abstract Pickering emulsions (PEs) are particle‐stabilized multiphase systems with promising features for synthetic applications. Described here is a novel, simplified set‐up employing catalytically active whole cells for simultaneous emulsion stabilization and synthetic reaction. In the stereoselective carboligation of benzaldehyde to ( R )‐benzoin catalyzed by a benzaldehyde lyase in E. coli , the set‐up yielded maximum substrate conversion within very short time, while economizing material demand and waste. Formation and activity of freshly produced PEs were enhanced when the catalytic whole cells were covered with hydrophobic silicone prior to PE formation. Benchmarked against other easy‐to‐handle whole‐cell biocatalysts in pure organic solvent, neat substrate, an aqueous emulsion in substrate, and a micro‐aquatic system, respectively, the cell‐stabilized PE outperformed all other systems by far.
Figure S7 from Type I IFN Receptor Signaling Controls IL7-Dependent Accumulation and Activity of Protumoral IL17A-Producing γδT Cells in Breast Cancer (2023)

&lt;p&gt;Early IL-7 depletion reduces accumulation of IL-17A+ CD3bright gamma/delta T cells in 4T1.2 breast cancer model&lt;/p&gt;
Digital Image Management (Archiving) (2007)

A DIGITAL IMAGE ARCHIVING SYSTEM MAY INCLUDE ALL OF THE FEAtures and components of a full image measurement system, the difference being that the primary purpose of archiving is to provide efficient and convenient yet powerful methods for capturing, identifying, storing, and retrieving digital images and associated information rather than to extract structure measurement data. Such a system may include sophisticated database software or simple filing schemes for identifying images by a range of user definable classifications and keyword associations. As with digital image measurement systems the selection of archiving must be based upon an evaluation of existing and projected needs.
A comparative study of motor imagery based BCI classifiers on EEG and iEEG data (2019)

There are many state-of-the-art Brain Computer Interface (BCI) classification algorithms designed to perform well when applied to signals acquired using electroencephalography (EEG). EEG has the advantage of being non-invasive in nature, easy to use, and effective in capturing signals in the mu (7-13 Hz) and beta (13-30 Hz) bands during motor imagery tasks. However, EEG recordings are more susceptible to movement artifacts and capture a lower frequency of neural activity when compared with invasive techniques such as electrocorticography (ECoG) or intracranial EEG (iEEG). In this paper, we analyze the performance of four different EEG motor imagery classification algorithms (both classical machine learning methods and deep learning-based methods) on a two-hand motor imagery task using both EEG and iEEG data sets. Using various feature visualization techniques, we provide insight into why deep learning-based classifiers designed to learn features end-to-end may perform better than the classical machine learning-based models. We also showed on average iEEG-based motor imagery BCIs, using our iEEG data set, do not perform as well as EEG-based BCIs. This work provides a starting point for the implementation of BCI applications using iEEG data.
Cells from Testis for Transplantation in the CNS (2000)

Neural transplantation as a therapy for neurodegenerative diseases has received much attention over the past two decades. The possibility that disease progress could be arrested and function restored raised hopes that a new treatment, particularly for Parkinson’s disease (PD), was imminent. Results with experimental models were promising, and, although clinical results have been mixed, there have been successes (see Lindvall, 1997, for a review). However, using fetal tissue as a source of neurons for transplantation in neurodegenerative diseases, such as PD or Huntington’s disease (HD), will always limit the acceptability and availability of this form of treatment. The ethical debate over the use of fetal tissue will not be resolved, and the practice of using this tissue is subject to the capriciousness of current public opinion and well-meaning government regulators. Furthermore, neuronal survival within the graft is often limited, necessitating the use of more tissue. In grafting studies in the hemiparkinsonian rat model, survival of dopaminergic neurons was estimated to be between 5–10% of the grafted dopaminergic (DA-ergic) neurons, based on the number of tyrosine hydroxylase (TH)-positive, immunohistochemically labeled neurons present in surviving grafts (Brundin and Bjorklund, 1987; Brundin et al., 1988). This number was compared to the number of immunostained DA-ergic neurons in the substantia nigra of adult mice, rats, and humans, as determined by (1983).
Heterographene BCN phase prepared at high pressures and temperatures: Formation kinetics, structure, and properties (2014)

We report the structure and some characteristics of powder particles of an h-BCN heterographene phase synthesized from boron-melamine mixtures in the pressure range from 3.5 to 7.0 GPa. This phase has the basic hexagonal boron nitride lattice and contains up to 10 at % carbon uniformly distributed over its sites. The resistivity of the h-BCN phase depends on its structural perfection and ranges from several Ω cm to tens of kΩ cm. This phase is a degenerate semiconductor with an activation energy substantially lower than kT throughout the temperature range studied, from 5 to 300 K.
Age-related Patterns of Vestibular Dysfunction in Dizziness and Imbalance: A Review of Vestibular Testing Results Among 1,116 Patients (2021)

Among patients presenting balance-related complaints, a majority demonstrate at least one abnormality on vestibular testing. While caloric abnormalities occur across the life span, patients ≥60 years of age are more likely to have abnormal results in random saccades, positional, Dix-Hallpike testing, and posturography, with greater effect sizes in tests of central function. While the causes of imbalance and vertigo remain multifactorial, vestibular dysfunction can be considered a major contributor to balance dysfunction in the elderly population and should be thoroughly evaluated.
Table S2 from Flaxseed Consumption Inhibits Chemically Induced Lung Tumorigenesis and Modulates Expression of Phase II Enzymes and Inflammatory Cytokines in A/J Mice (2023)

&lt;p&gt;List of primers for RT-qPCR&lt;/p&gt;
Supplementary Table S3 from Development and Validation of Urine-based Peptide Biomarker Panels for Detecting Bladder Cancer in a Multi-center Study (2023)

&lt;p&gt;Supplementary Table S3. Shortlist of significant biomarkers, as derived based on statistical analysis between primary UBC cases (n=341) and urological controls (n=110) - including negative after cystoscopy samples, samples from patients with hematuria and patients with benign urological diseases. Wilcoxon test was applied to assess the significant differences. The significant biomarkers were subsequently compared for their trend of regulation among the different centers. Only those that were identified with the same regulation in at least two clinical centres were further considered for the generation of the peptide biomarker model.&lt;/p&gt;
Plaster Hydration at Different Plaster-to-Water Ratios: Acoustic Emission and 3-Dimensional Submicrometric Simulations (2012)

To relate the dynamics of the reaction to the structure and properties of the resulting material, we develop a three-dimensional submicrometric simulation model for plaster hydration, valid in the entire range of plaster-to-water ratios. Stochastic rules govern the growth without overlap of gypsum needles. The precipitation process is assumed to drive the dissolution of plaster grains. The comparison of the simulation results with optical microscopy images at different times and acoustic emission monitoring during the reaction enable us to assign physical values to the length and time scales and to the main parameters of the model. In agreement with X-ray microtomography images of plaster available online (http://visiblecement.nist.gov/plaster.html), the simulation model predicts that hydration of plaster of Paris is incomplete for the usual values of plaster-to-water ratios used in industry.
A robust blind watermarking scheme based on distributed source coding principles (2000)

We propose a powerful new solution to the multimedia watermarking problem by exploiting its duality with another problem for which we have recently made pioneering constructive contributions. This latter problem is that of distributed source coding, or compression of correlated sources that are distributed. We show how these two seemingly unrelated problems are actually duals of each other. We exploit this duality by transforming our recently introduced powerful constructive framework for the distributed compression problem in [13] to a corresponding dual framework for the watermarking problem. Simulations expose the significant performance gains attained by our proposed watermarking approach and reveal its exciting potential for next-generation watermarking techniques. This can be accredited to the exploitation of the dual roles played by source codes and channel codes in the two problems.
Author Correction: The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics (2022)

The originally published article contained an error in Table 2 in which the study on L. gasseri CP2305 was wrongly attributed to reference 155; it should have cited reference 15: Nishida et al. Para- psychobiotic Lactobacillus gasseri CP2305 ameliorates stress- related symptoms and sleep quality. J. Appl. Microbiol. 123, 1561–1570 (2017). This error has now been corrected in the HTML and PDF versions of the article.
A real-life exposure evaluation index for mobile phones based on SAR and TRP measurements data: the SAROTA index (2010)

International audience
A Control-Theoretic Approach to Adaptive Video Streaming in Dense Wireless Networks (2015)

Recently, the way people consume video content has been undergoing a dramatic change. Plain TV sets, that have been the center of home entertainment for a long time, are losing ground to hybrid TVs, PCs, game consoles, and, more recently, mobile devices such as tablets and smartphones. The new predominant paradigm is: watch what I want, when I want, and where I want. The challenges of this shift are manifold. On the one hand, broadcast technologies such as DVB-T/C/S need to be extended or replaced by mechanisms supporting asynchronous viewing, such as IPTV and video streaming over best-effort networks, while remaining scalable to millions of users. On the other hand, the dramatic increase of wireless data traffic begins to stretch the capabilities of the existing wireless infrastructure to its limits. Finally, there is a challenge to video streaming technologies to cope with a high heterogeneity of end-user devices and dynamically changing network conditions, in particular in wireless and mobile networks. In the present work, our goal is to design an efficient system that supports a high number of unicast streaming sessions in a dense wireless access network. We address this goal by jointly considering the two problems of wireless transmission scheduling and video quality adaptation, using techniques inspired by the robustness and simplicity of proportional-integral-derivative (PID) controllers. We show that the control-theoretic approach allows to efficiently utilize available wireless resources, providing high quality of experience (QoE) to a large number of users.
<title>On the detection of pornographic digital images</title> (2003)

The paper addresses the problem of distinguishing between pornographic and non-pornographic photographs, for the design of semantic filters for the web. Both, decision forests of trees built according to CART (Classification And Regression Trees) methodology and Support Vectors Machines (SVM), have been used to perform the classification. The photographs are described by a set of low-level features, features that can be automatically computed simply on gray-level and color representation of the image. The database used in our experiments contained 1500 photographs, 750 of which labeled as pornographic on the basis of the independent judgement of several viewers.
Novel high-power radio-frequency sources for mobile ionospheric heating (2016)

The ionosphere plays an important role in the performance of critical civilian and defense communication systems. Perturbation studies of the ionosphere allow us to investigate the ionosphere and improve the performance of communications that rely on the ionosphere as well as develop new applications. A key instrument in ionospheric modification is the ionospheric heater, a powerful high frequency transmitter that perturbs the properties of the ionospheric plasma by modulating the electron temperature at preselected altitudes. The latest technology uses stationary facilities, among which HAARP is the largest. There are numerous benefits from using mobile ionospheric heaters (MIHs). Such a mobile system would allow investigators to conduct the research at different latitudes without building a costly permanent installation. These mobile sources would be substantially smaller than HAARP and located on a barge-size platform. A mobile heater for ionospheric modification studies requires a new megawatt class of RF (3-10 MHz) source operating with an antenna that is roughly 1/100 in area of a HAARP antenna [2]. In order to deliver to the ionosphere, an effective power density comparable to that of HAARP, the total source power must be in the range of up to 100 MW, placing a premium on efficiency. The present paper describes some of the technical advances in the development of such sources (inductive output tubes, IOTs): a novel electron gun, which allows the D-class operation of a MW-level IOT without interception of an electron beam by grid electrodes, a prototyping test-stand, two types of modulators capable of driving the mod-anode of a MW level gun and a tunable constant impedance cavity operating in the desired frequency range.
Effect of Roller Profile on Cylindrical Roller Bearing Life Prediction (2000)

Four roller profiles used in cylindrical roller bearing design and manufacture were analyzed using both a closed form solution and finite element analysis (FEA) for stress and life. The roller profiles analyzed were flat, tapered end, aerospace, and fully crowned loaded against a flat raceway. Four rolling-element bearing life models were chosen for this analysis and compared. These were those of Weibull, Lundberg and Palmgren, Ioannides and Harris, and Zaretsky. The flat roller profile without edge loading has the longest predicted life. However, edge loading can reduce life by as much as 98 percent. The end tapered profile produced the highest lives but not significantly different than the aerospace profile. The fully crowned profile produces the lowest lives. The resultant predicted life at each stress condition not only depends on the life equation used but also on the Weibull slope assumed. For Weibull slopes of 1.5 and 2, both Lundberg-Palmgren and Iaonnides-Harris equations predict lower lives than the ANSI/ABMAJISO standards. Based upon the Hertz stresses for line contact, the accepted load-life exponent of 10/3 results in a maximum Hertz stress-life exponent equal to 6.6. This value is inconsistent with that experienced in the field.
Reconnaissance of alluvial fans as potential sources of gravel aggregate, Santa Cruz River valley, Southeast Arizona (2002)

This investigation was conducted to provide information on the aggregate potential of alluvial fan sediments in the Santa Cruz River valley. Pebble lithology, roundness, and particle size were determined in the field, and structures and textures of alluvial fan sediments were photographed and described. Additional measurements of particle size on digital photographs were made on a computer screen. Digital elevation models were acquired and compiled for viewing the areal extent of selected fans.
Some general observations on tubular reactor stability (1967)

Abstract A sufficient condition under which a tubular reactor with axial diffusion is globally stable is derived by use of the maximum principle for parabolic equations. It is shown that by use of some topological concepts the asymptotic stability of a steady state can be determined without the necessity of performing any computations. If a unique steady state exists it is asymptotically stable. If three steady states exist, the high and low temperature steady states are asymptotically stable, while the intermediate one is unstable.
Low-noise, GHz repetition-rate femtosecond lasers and frequency combs: implementation and applications (2013)

We report on advances and unique characteristics of high repetition-rate (&gt;1 GHz) Ti:Sapphire, Er-fiber, and Yb-fiber femtosecond laser frequency combs, and their applications in high-speed, high resolution optical sampling and astrophysical spectrograph calibration.