gebhart/patrepeval huggingface dataset:
Transfer-Printed Cuprous Iodide (CuI) Hole Transporting Layer for Low Temperature Processed Perovskite Solar Cells (2022)

Perovskite solar cells (PSCs) have achieved significantly high power-conversion efficiency within a short time. Most of the devices, including those with the highest efficiency, are based on a n-i-p structure utilizing a (doped) spiro-OMeTAD hole transport layer (HTL), which is an expensive material. Furthermore, doping has its own challenges affecting the processing and performance of the devices. Therefore, the need for low-cost, dopant-free hole transport materials is an urgent and critical issue for the commercialization of PSCs. In this study, n-i-p structure PSCs were fabricated in an ambient environment with cuprous iodide (CuI) HTL, employing a novel transfer-printing technique, in order to avoid the harmful interaction between the perovskite surface and the solvents of CuI. Moreover, in fabricated PSCs, the SnO<sub>2</sub> electron transport layer (ETL) has been incorporated to reduce the processing temperature, as previously reported (n-i-p) devices with CuI HTL are based on TiO<sub>2</sub>, which is a high-temperature processed ETL. PSCs fabricated at 80 °C transfer-printing temperature with 20 nm iodized copper, under 1 sun illumination showed a promising efficiency of 8.3%, (J<sub>SC</sub> and FF; 19.3 A/cm<sup>2</sup> and 53.8%), which is comparable with undoped spiro-OMeTAD PSCs and is the highest among the ambient-environment-fabricated PSCs utilizing CuI HTL.
Sesquiterpenes from Essential Oils and Their Anticancer Potential (2023)

Roland Institute of Pharmaceutical Sciences, Berhampur-760010, Odisha, India; Pharmacy Academy, IFTM University, Lodhipur Rajput, Moradabad-244102, Uttar Pradesh; Department of Mathematics and Natural Sciences, College of Sciences and Human Studies, Prince Mohammad Bin Fahd University, Al Khobar, Kingdom of Saudi Arabia; drbiswamohansahoo@gmail.com; bimalbanik10@gmail.com; bbanik@pmu.edu.sa Sesquiterpenes from Essential Oils and Their Anticancer Potential
DNA methylation profiles of lung tumors. (2001)

Aberrant methylation of CpG islands in promoter regions of tumor cells is one of the major mechanisms for silencing of tumor suppressor genes. We determined the frequency of aberrant promoter methylation of the p16, adenomatous polyposis coli (APC), H-cadherin (CDH13), glutathione S-transferase P1 (GSTP1), O6-methylguanine-DNA-methyltransferase (MGMT), retinoic acid receptor beta-2 (RAR beta), E-cadherin (CDH1), and RAS association domain family 1A (RASSF1A) genes in 198 tumors consisting of small cell lung cancers [SCLCs (n = 43)], non-small cell lung cancers [NSCLCs (n = 115)], and bronchial carcinoids (n = 40). The profile of methylated genes in the two neuroendocrine tumors (SCLC and carcinoids) were very different from that of NSCLC. However, whereas the overall pattern of aberrant methylation of carcinoids was similar to that of SCLC, carcinoids had lower frequencies of methylation for some of the genes tested. There were also significant differences in the methylation profiles between the two major types of NSCLC, adenocarcinoma and squamous cell carcinoma. We performed cluster analysis and found that SCLCs clustered with other SCLCs and carcinoids but not with NSCLCs, whereas the NSCLCs tended to cluster together. Within NSCLCs, adenocarcinomas and squamous cell carcinomas clustered with their respective histological types. Finally, we compared the methylation profiles of SCLC and NSCLC tumors and their respective cell lines (n = 44). In general, methylation frequencies were higher in tumor cell lines, but these differences were seldom significant. Thus, tumor cell lines appear to be suitable models to study aberrant DNA methylation. We conclude that SCLC, carcinoids, squamous cell carcinomas, and adenocarcinomas of the lung have unique profiles of aberrant methylation. Our findings should help us understand differences in the pathogenetic mechanisms of lung cancers.
Manganese-Catalyzed C–H Activation (2016)

Manganese is found in the active center of numerous enzymes that operate by an outer-sphere homolytic C–H cleavage. Thus, a plethora of bioinspired radical-based C–H functionalizations by manganese catalysis have been devised during the past decades. In contrast, organometallic C–H activation by means of manganese catalysis has emerged only recently as an increasingly viable tool in organic synthesis. These manganese(I)-catalyzed processes enabled a variety of C–H functionalizations with ample scope, which very recently set the stage for substitutive C–H functionalizations. The versatile manganese catalysis largely operates by an isohypsic, thus redox-neutral, mode of action through chelation assistance, and provided step-economical access to structurally divers compounds of relevance to inter alia bioorganic, agrochemical, and medicinal chemistry as well as the material sciences.
Ectodomain cleavage and shedding of the type III transforming growth factor‐β receptor in lung membranes (1999)

Previous studies from our laboratory [Philip, A. & O'Connor-McCourt, M. D. (1991) J. Biol. Chem. 266, 22290--22296] have shown that the lung exhibited the highest uptake of circulating [125I]-transforming growth factor-beta1 (TGF-beta1) on a per gram basis. This observation, together with the lack of information on TGF-beta receptor expression in the lung, prompted us to attempt to characterize TGF-beta receptors in this tissue. In the present report we show that the type III TGF-beta receptor is the most abundant TGF-beta binding protein in rat lung membranes and that it exhibits a 10-fold higher affinity for TGF-beta2 than for TGF-beta1. We observed that the majority of the type III receptor population in lung membranes is cleaved at a site in the central portion of the ectodomain, the resulting two fragments (95 kDa and 58 kDa) being held together by disulfide bonds. Furthermore, we demonstrate that a soluble form of the ectodomain of the type III receptor is shed from rat lung membranes in an efficient manner, with protease cleavage occurring at a site close to the transmembrane domain. This shedding is controllable by temperature, thus providing a system to study the mechanism of ectodomain release. Using this system, we show that the shedding is inhibited by prior ligand binding and by membrane solubilization. The identification of a membrane preparation which exhibits controllable and quantitative release of the type III receptor ectodomain provides a unique cell-free system for further studies of the mechanism of shedding of the type III TGF-beta receptor ectodomain.
Anion‐Regulated Hydroxysulfide Monoliths as OER/ORR/HER Electrocatalysts and their Applications in Self‐Powered Electrochemical Water Splitting (2018)

Abstract Trifunctional electrocatalysis for the oxygen evolution reaction, oxygen reduction reaction, and hydrogen evolution reaction constitutes the bottleneck of various sustainable energy devices and systems including rechargeable metal–air batteries and overall water splitting. Emerging macroscopically nanostructured catalysts are strongly requested for superior electrocatalytic activities and practical applications. Here, a 3D hydroxysulfide monolith with anion‐regulated NiFe hydroxysulfide nanosheets is rationally proposed. With abundant active sites and unique structure, the as‐obtained hydroxysulfide monolith exhibits superior electrocatalytic performance in oxygen evolution, hydrogen evolution, and oxygen reduction in alkaline electrolyte. When directly serving as electrodes, a small charge/discharge voltage gap of 0.76 V at 2.0 mA cm −2 and a high peak power density of 248 mW cm −2 are achieved for the liquid Zn−air batteries, and a low cell voltage of 1.62 V at 10 mA cm −2 is detected for water splitting units. When two Zn−air batteries are serially connected to power the water splitting unit, bulky O 2 and H 2 bubbles are continuously generated on both the composite electrodes. This work demonstrates an effective strategy for controllable anion regulation and rational design of the 3D self‐supporting hydroxysulfides, which is also enlightening for other advanced energy materials and diverse applications.
Le Silence du Bonheur and the House of Forgiveness: Space and Silence in Flood (2002)

Katrin Meise reformulates Wittgenstein's famous dictum-"What we cannot speak about, we must pass over in silence"-in a way that is particularly germane to a reading of Warren's novel Flood: ''What we pass over in silence, we must speak about." Warren establishes a complex aesthetic that incorporates silence into the circuit of discourse, forcing characters to confront the limitations of language, even as they realize the redemptive power of telling a "true" story.
Stellar photometry and astrometry with discrete point spread functions (2005)

Abstract The key features of the matphot algorithm for precise and accurate stellar photometry and astrometry using discrete point spread functions (PSFs) are described. A discrete PSF is a sampled version of a continuous PSF, which describes the two-dimensional probability distribution of photons from a point source (star) just above the detector. The shape information about the photon scattering pattern of a discrete PSF is typically encoded using a numerical table (matrix) or an FITS (Flexible Image Transport System) image file. Discrete PSFs are shifted within an observational model using a 21-pixel-wide damped sinc function, and position-partial derivatives are computed using a five-point numerical differentiation formula. Precise and accurate stellar photometry and astrometry are achieved with undersampled CCD (charge-coupled device) observations by using supersampled discrete PSFs that are sampled two, three or more times more finely than the observational data. The precision and accuracy of the matphot algorithm is demonstrated by using the c-language mpd code to analyse simulated CCD stellar observations; measured performance is compared with a theoretical performance model. Detailed analysis of simulated Next Generation Space Telescope observations demonstrate that millipixel relative astrometry and mmag photometric precision is achievable with complicated space-based discrete PSFs.
Dielectric Breakdown of Gate Oxides: Physics and Experiments (2009)

This chapter contains sections titled: Introduction Physics of Degradation and Breakdown Physical Models for Oxide Degradation and Breakdown Experimental Results of Oxide Breakdown Post-Breakdown Phenomena References
Quantifying Domain Textures in Lead Zirconate Titanate Using 022:202 and 220 Diffraction Peaks (2005)

Determination of the domain textures in many lead zirconate titanate (PZT) piezoelectrics can be complicated by the presence of second phases, internal strains and small differences in lattice parameters for the commonly used 002 and 200:020 peaks. The domain texture is influenced by the applied polarization necessary for these materials to demonstrate piezoelectricity. In this paper we explore the use of 022:202 and 220 peaks for evaluating the domain textures and helping resolve the complexities of texture analysis in the presence of multiple phases. The two materials explored in this paper include a nominally single phase tetragonal PZT material and a mixed phase tetragonal-monoclinic lead magnesium niobate (PMN)-PZT alloy.
Developing Animal Models for Optimizing the Musculoskeletal Repair Potential of Emerging Human Progenitor Cell Therapies (2014)

Abstract : This 5 component award made significant advances to achieve most of the proposed objectives of the initial award. Most important was the demonstration that human marrow stromal cells are capable of making human bone in murine skeletal repair defects while commercial higher passage stromal preparations are ineffective in vivo. Human ES and induced pleuripotential cells can also produce bone and cartilage in vivo when grown under unique conditions prior to implantation. Standard mesenchymal culture condition do not preserve in vivo bone forming capability. A new source of adults stromal cells were identified in normal murine skeletal muscle that appear to be the initiator of heterotopic ossification. This cell source may have practical regenerative implication. Both weight bearing and growth factor releasing scaffold were evaluated in vivo to reveal properties that cannot be appreciated in vitro characterization studies. The importance of fixation rigidity became a central focus of our repair strategies, and image analysis programs that account for the changes in tissue dynamics during fracture repair were develop to access the effect of strategies that influence long bone healing. The method for achieving fixation rigidity had a major influence on the design of new long bone critical segmental defect models for both the mouse femur and tibia. The models are accepting of human cell engraftment and the fixation devices can be remove once the defect is closed to demonstrate both functional and mechanical competence.
SCTP Handover: Analysis and Experimentations (2005)

+ This research was supported by the MIC, Korea, under the ITRC support program supervised by the IITA Abstract: Stream Control Transmission Protocol (SCTP) is a new end-to-end transport protocol, which can be used to support the mobility of mobile terminals. This paper analyzes the handover latency for the single-homing mobile terminals. We then show the experimental results of the SCTP handover in terms of the handover latency for the two different movement patterns: linear and crossover patterns. For the linear movement pattern, it is shown that the SCTP handover latency may severely depend on the handover delay at the underlying link layer. In the case of the crossover movement pattern, we see that the throughput of the data transmission could be degraded, as the crossover movements occur more frequently.
Vortex–leading-edge interaction (1982)

Visualization of successive vortices impinging upon the leading edge of a wedge reveals patterns of deformation of each incident vortex; for certain offsets of the edge with respect to the incident vortex there is pronounced vortex shedding from the leading edge, whereby the shed vortex has a vorticity orientation opposite to that of the incident vortex. Simultaneous consideration of this visualization interaction and the force induced on the wedge gives the relation between the nature of the interaction mechanism and the relative magnitude and phase of the force exerted on the wedge. The amplitude of the induced force is found to be a strong function of the transverse offset of the leading edge with respect to the incident vortex and the degree of vorticity shedding from the leading edge. Application of Stuart's vortex model to the incident vortices provides a means for approximating the phase and relative amplitude of the induced force as a function of the transverse offset of the leading edge.
CYTOCHEMICAL LOCALIZATION OF THE GASTRODERMAL GLYCOCALYX OF <i>GORGODERINA ATTENUATA</i> AND <i>HAEMATOLOECHUS MEDIOPLEXUS</i> (1971)

The filamentous surface coating on the caecal cytoplasmic extensions of Gorgoderina attenuata and Haematoloechus medioplexus is found to contain macromolecular diglycols as cytochemically demonstrated by the PATCO method. This cytochemical evidence suggests that these structures can now be characterized as “glycocalyces”.
A 1.9nJ/bit, 5Mbps multi-standard ISM band wireless transmitter using fully digital PLL (2013)

This paper presents an energy efficient transmitter for multi-standard applications (IEEE802.15.4, BLE, 5Mbps) in ISM2.4GHz band. It incorporates a fully digital PLL with two point modulation to achieve upto 5Mbps data rate at 9.5mW power consumption (including all power management blocks) at 0dBm output power, leading to 1.9nJ/b efficiency. The proposed digital PLL uses a counter based area and power efficient re-circulating TDC, current reuse low area DCO using resistive tail, process compensated high speed divider, class-AB PA stages, and fully integrated on-chip LDOs. The entire transmitter occupies 0.35mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> Silicon area in a 65nm digital CMOS process.
Significance of endogenous glucocorticoid sensitivity for airway eosinophilia in a murine model of allergy (2004)

Inhibition with RU and ME increased eosinophilia in the bone marrow compared to controls (p < 0.05). Eosinophilia in bronchoalveolar lavage fluid increased in the sensitized groups compared to controls, but there were no differences between the sensitized groups. CD3+ and CD4+ cells were increased in the nasal mucosa as a result of treatment with RU and ME.
Supplementary Table 1 from Inhibition of Histone Demethylase JMJD1A Improves Anti-Angiogenic Therapy and Reduces Tumor-Associated Macrophages (2023)

&lt;p&gt;PDF file - 37K, The sequence of specific primers for angiogenic factors and JMJD1A in real-time polymerase chain reaction analysis.&lt;/p&gt;
Current status and future prospects of poly-Si devices (1994)

Thin-film polysilicon insulated-gate field effect transistors deposited on glass substrates are the subject of worldwide research and development activity. The greatest motivation for this is their application to flat-panel displays, including, in particular, active-matrix liquid crystal displays (AMLCDs), where they offer several important advantages over the more mature amorphous silicon thin-film transistor (TFT) technology. One of these is the ready availability of both n-type and p-type poly-Si TFTs. Polysilicon-on-glass CMOS TFT technology may be used to fabricate AMLCD drivers on the display substrate; it can also be used in a variety of other applications such as printers, scanners, smart sensors and neural networks. This review identifies the major achievements and key issues in the development of poly-Si TFT technology for both display and nondisplay applications.
“Apoptotic” Myocytes in Infarct Area in Rabbit Hearts May Be Oncotic Myocytes With DNA Fragmentation (1998)

DNA fragmentation occurs in the myocytes that had already shown irreversibly oncotic, but not apoptotic, ultrastructures with ischemia and/or reperfusion. Therefore, DNA fragmentation itself does not always mean apoptosis, and so-called apoptotic infarcted myocytes may belong to a category of cell death other than apoptosis.
A CONVENIENT NEW METHOD FOR 2-HYDROXY-6,7,8,9- TETRAHYDRO-5H-BENZOCYCLOHEPTEN-5-ONE† (2003)

A novel approach has been developed for the synthesis of 2-hydroxy-6,7,8,9-tetrahydro-5//benzocyclohepten-5-one is reported using 4-carboxybutyl triphenyl phosphonium bromide (Wittig salt) in excellent yield.
Enabling Tractable Exploration of the Performance of Adaptive Mesh Refinement. (2016)

Abstract not provided.
Shotgun Drug Repurposing Biotechnology to Tackle Epidemics and Pandemics (2020)

In this manuscript we highlight consensus between the list of drugs currently in clinical trials to treat COVID-19, the worldwide pandemic caused by severe acute respiratory coronavirus 2 (SARS-CoV-2), and the list of predictions made using our shotgun drug discovery, repurposing, and design platform known as CANDO (Computational Analysis of Novel Drug Opportunities). We make the argument that increased funding and development for drug repurposing biotechnology like ours will help combat the inevitable pathogenic outbreaks of the future.
Cytomegalovirus Infection and Risk of AIDS in Human Immunodeficiency Virus-Infected Hemophilia Patients (1993)

The effects of prevalent and incident cytomegalovirus (CMV) infection on human immunodeficiency virus (HIV) disease progression were examined in 393 hemophilia patients with known dates of HIV seroconversion. Of the cases, 191 (49%) had IgG antibody to CMV in their earliest stored sera (median date, November 1983). CMV-seropositive subjects were one and a half times more likely to develop AIDS, and they were also older than CMV-negative subjects. Adjusted for age, CMV seropositivity was not associated with the development of AIDS. In age-adjusted analyses, CMV-seropositive subjects had a small, but statistically insignificant, decrease in survival after HIV seroconversion. Older subjects were more likely to CMV seroconvert by the time of their latest available serum samples (P = .03). CMV seroconverters were five times more likely to develop clinical CMV disease than were subjects initially CMV-positive (P = .02). To avoid this source of serious morbidity, CMV-seronegative hemophiliacs with HIV infection should not be exposed to cellular blood products or body fluids from CMV-seropositive donors.
Insulin- and leptin-regulated fatty acid uptake plays a key causal role in hepatic steatosis in mice with intact leptin signaling but not inob/obordb/dbmice (2010)

Hepatic steatosis results from several processes. To assess their relative roles, hepatocellular long-chain fatty acid (LCFA) uptake was assayed in hepatocytes from C57BL/6J control mice, mice with steatosis from a high-fat diet (HFD) or 10%, 14%, or 18% ethanol (EtOH) in drinking water [functioning leptin-signaling groups (FLSGs)], and ob/ob and db/db mice. V(max) for uptake was increased vs. controls (P < 0.001) and correlated significantly with liver weight and triglycerides (TGs) in all FLSG mice but was minimally or not increased in ob/ob and db/db mice, in which liver weights and TGs greatly exceeded projections from regressions in FLSG animals. Coefficients of determination (R(2)) for these FLSG regressions suggest that increased LCFA uptake accounts for ∼80% of the increase in hepatic TGs within these groups, but increased lipogenic gene expression data suggest that enhanced LCFA synthesis is the major contributor in ob/ob and db/db. Got2, Cd36, Slc27a2, and Slc27a5 gene expression ratios were significantly upregulated in the EtOH groups, correlating with sterol regulatory element binding protein 1c (SREBP1c) and V(max), but only Cd36 expression was increased in HFD, ob/ob, and db/db mice. Comparison of V(max) with serum insulin and leptin suggests that both hormones contribute to upregulation of uptake in the FLSG animals. Thus, increased LCFA uptake, reflecting SREBP1c-mediated upregulation of four distinct transporters, is the dominant cause of steatosis in EtOH-fed mice. In ob/ob and db/db mice, increased LCFA synthesis appears more important. In FLSG animals, insulin upregulates hepatocellular LCFA uptake. Leptin appears to upregulate LCFA uptake or to be essential for full expression of upregulation by insulin.
Countermeasures Against Noise Generated Around Steel Railway Bridge (2005)

Steel railways bridges characteristically tend to generate high-level noise. Its reason is that not only high-level of structure-borne noise generated but also rolling noise is directly transmitted to trackside. Therefore, many efforts have been so far devoted to decrease the degree of vibration and noise of steel railway bridges. The countermeasures against noise generated adjacent to steel railways bridges are classified into the following five technologies: decrease of rolling noise, isolation of vibration, vibration damping, isolation of noise and noise absorption.Many of them have adopted application of rubber materials for the purpose as intended. This paper describes the outline of these technologies to decrease the vibration and noise attributed to steel railway bridges.
Alternative soaking media for the FDA procedure in the detection of salmonella from tomatoes and spinach leaf using phage magnetoelastic biosensors (2016)

Efforts were made to incorporate the phage Magnetoelastic (ME) biosensor in FDA's Spinach Soaking procedures according to FDA 2015 BAM method. Three soaking materials (Lactose broth, LB broth, and Peptone water) and various soaking times were investigated. Using merely 100 <i>Salmonella </i>cells spiked on the produce surfaces, the phage biosensors detected <i>Salmonella </i>within 5 hours when soaking tomatoes in LB broth as opposed to taking up to 24 hours. <i>Salmonella </i>was detected on spinach leaves within 7 hours. These phage ME biosensors provide a promising rapid detection platform using LB broth in FDA's soaking procedures while shortening the incubation period.