gebhart/patrepeval huggingface dataset:
Cyclopentadienone Ketals (1965)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCyclopentadienone KetalsPhilip E. Eaton and Richard A. HudsonCite this: J. Am. Chem. Soc. 1965, 87, 12, 2769–2771Publication Date (Print):June 1, 1965Publication History Published online1 May 2002Published inissue 1 June 1965https://pubs.acs.org/doi/10.1021/ja01090a052https://doi.org/10.1021/ja01090a052research-articleACS PublicationsRequest reuse permissionsArticle Views629Altmetric-Citations51LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Analytical model for low-frequency noise in amorphous chalcogenide-based phase-change memory devices (2009)

Low-frequency noise has been experimentally characterized in the disordered insulating phase of chalcogenide-based phase-change memory (PCM) devices. An analytical model of noise based on the two-level systems (TLS) theory has been developed. In this framework we suggest that the origin of the 1/fγ noise in the conductivity of amorphous chalcogenides has to be ascribed to the TLS-induced fluctuations of the mean trap energy in the material. The model allows to quantitatively account for noise magnitude dependence on both voltage and temperature in the readout region of the memory device. Besides, our equations well describe the noise behavior as a function of the drift phenomenon, coherently with existing structural relaxation theories. Measurements and model results show that the noise-to-signal ratio (N/S) in the readout region of the cell is constant with respect to bias; hence there is no particular readout voltage that minimizes N/S. Furthermore, the analysis of noise data with cell scaling confirms that noise in PCMs is mainly due to the bulk properties of the chalcogenide employed rather than to interfacial effects.
Noninvasive measurement of chip currents in IGBT modules (2002)

Modern IGBT modules employ a number of die connected in parallel. Measurement of the effects of layout topology and variations in chip parameters and temperatures requires a noninvasive current measurement system. This paper describes a method for the noninvasive measurement of currents in modern power devices. It discusses methods for incorporating the system into test modules and shows results obtained from measurements on IGBTs. The system consists of miniature magnetic field probes and active wide bandwidth integrators. The probes are small (6 mm), immune to stray fields and are insulated up to several kV. This system has been used to show current redistribution between IGBT chips in a module at turn off and temperature dependent switching of IGBT chips. Furthermore, switching-loss distribution in parallel IGBT chips and gate topology effects were investigated.
Delivery of stem cells to the brain: potential for treatment of neurodegenerative disease (2015)

Stem cell therapy is a promising strategy to treat neurodegenerative diseases, including Alzheimer's and Parkinson's diseases. However, for stem cell therapy to be considered for clinical use, new delivery methods need to be developed. We have used focused ultrasound (FUS) as a method to induce transient opening of the blood-brain barrier (BBB) to promote the passage of therapeutic stem cells into the brain.
8 Kev X-Ray Zone Plates (1989)

Sputtered-sliced transmissive x-ray zone plates consisting of concentric rings of Al and Cu have been fabricated and tested using the 8.04 keV k-a line from Cu. Due to the need for high aspect ratios for this 1.54 A radiation, magnetron sputtering onto a rotating opaque central wire was chosen as the fabrication method. Both the fabrication technology and initial results are presented.
Importance of intellectual property generated by biomedical research at universities and academic hospitals (2017)

Biomedical research has many different facets. Researchers and clinicians study disease biology and biochemistry to discover novel therapeutic targets, unravel biochemical pathways and identify biomarkers to improve diagnosis, or devise new approaches to clinically manage diseases more effectively. In all instances, the overall goal of biomedical research is to ensure that results thereof (such as a therapy, a device, or a method which may be broadly referred to as "inventions") are clinically implemented. Most of the researchers' efforts are centered on the advance of technical and scientific aspects of an invention. The development and implementation of an invention can be arduous and very costly. Historically, it has proven to be crucial to protect intellectual property rights (IPR) to an invention (i.e., a patent) to ensure that companies can obtain a fair return on their investment that is needed to develop an academic invention into a product for the benefit of patients. However, the importance of IPR is not generally acknowledged among researchers at academic institutions active in biomedical research. Therefore this paper aims to (1) raise IP awareness amongst clinical and translational researchers; (2) provide a concise overview of what the patenting trajectory entails; and (3) highlight the importance of patenting for research and the researcher. <b>Importance for patients</b>: Adequate patent protection of inventions generated through biomedical research at academic institutions increases the probability that patients will benefit from these inventions, and indirectly enables the financing of clinical studies, mainly by opening up funding opportunities (e.g. specific grants aimed at start-ups, pre-seed and seed capital) that otherwise would not be accessible. As a consequence, patented inventions are more likely to become clinically tested and reach the market, providing patients with more treatment options.
Low resistivity lateral P–I–N junction formed by Ni–InGaAsP alloy for carrier injection InGaAsP photonic devices (2016)

Abstract In this study, we investigate low-resistivity InGaAsP lateral P–I–N junctions using Ni–InGaAsP alloy in conjunction with Zn diffusion. It is found that Ni–InGaAsP alloy is formed via a direct reaction between Ni and InGaAsP after annealing at more than 300 °C. The Ni–InGaAsP preserves the initial Schottky junction properties between Ni and InGaAsP, and thus exhibits an ohmic contact for n-InGaAsP and a Schottky contact for p-InGaAsP. Hence, the Ni–InGaAsP alloy can be used instead of the Si ion implantation process to form the P–I–N junction. The Ni–InGaAsP alloy exhibits significantly lower contact resistance and sheet resistance than Si implanted n + -InGaAsP. The InGaAsP lateral P–I–N junction formed with the Ni–InGaAsP alloy and Zn diffusion shows approximately 10 times lower access resistance than the n + -InGaAsP junction. Thus, we successfully achieve large on-current in the lateral P–I–N junction with the Ni–InGaAsP alloy. The fabrication procedure of the lateral P–I–N junction using the Ni–InGaAsP alloy is promising for carrier-injection photonic devices on the III–V CMOS photonics platform.
Synthesis and transition temperatures of some novel, chiral nematic, laterally attached, side-chain, siloxane polymers (1992)

The synthesis of a chiral nematic, laterally attached polymer, from an enantiotropic chiral nematic side-chain precursor is described, and ways of achieving selective esterifications of 2,4-dihydroxybenzoates are discussed. This compound is the first example of its kind to exhibit the chiral nematic phase in both the monomer and the derived polymer; the results show that the polymer has a lower chiral nematic to isotropic clearing point than the monomer.
Rational Solid-State Synthesis Routes for Inorganic Materials (2021)

Rational solid-state synthesis of inorganic compounds is formulated as catalytic nucleation on crystalline reactants, where contributions of reaction and interfacial energies to the nucleation barriers are approximated from high-throughput thermochemical data, and structural and interfacial features of crystals, respectively. Favorable synthesis reactions are then identified by a Pareto analysis of relative nucleation barriers and phase-selectivities of reactions leading to the target. We demonstrate the application of this approach in reaction planning for solid-state synthesis of a range of compounds, including the widely-studied oxides LiCoO2, BaTiO3 and YBa2Cu3O7, as well as other metal oxide, oxyfluoride, phosphate and nitride targets. Pathways for enabling retrosynthesis of inorganics are also discussed.
Ethnicity‐related skeletal muscle differences across the lifespan (2009)

Despite research and clinical significance, limited information is available on the relations between skeletal muscle (SM) and age in adults, specifically among Hispanics, African Americans (AA), and Asians. The aim was to investigate possible sex and ethnic SM differences in adults over an age range of 60 years. Subjects were 468 male and 1280 female adults (> or =18 years). SM was estimated based on DXA-measured appendicular lean-soft tissue using a previously reported prediction equation. Locally weighted regression smoothing lines were fit to examine SM trends and to localize age cutoffs; piecewise multiple linear regression models were then applied, controlling for weight and height, to identify age cutoffs for sex-specific changes in SM among the ethnic groups. The age of 27 years was identified for women and men as the cut-off after which SM starts to show a negative association with age. Both sexes had a similar ethnic pattern for expected mean SM at the age cutoff, with AA presenting the highest SM values, followed by Whites, Hispanics, and Asians. After the age cutoffs, the lowering of SM differed by ethnicity and sex: AA women showed the greatest SM lowering whereas Hispanic women had the least. Hispanic men tended to show a higher negative association of SM with age followed by AA and Whites. To conclude, significant sex and ethnic differences exist in the magnitude of negative associations of SM with age >27 years. Further studies using a longitudinal design are needed to explore the associations of ethnicity-related decline of SM with health risks.
Low loss optical ridge waveguides in a strained GeSi epitaxial layer grown on silicon (1990)

The realisation of single-mode ridge waveguides in a strained Si1−xGex epitaxial layer grown on silicon by MBE is reported. Measurements at λ = 1.3μm yield a refractive index enhancement of 2.2 × 10−3 for x = 0.01 and waveguide losses around 3–5 dB/cm.
Genetic Optimization and Simulation of a Piezoelectric Pipe-Crawling Inspection Robot (2006)

Using the Darwin2k development software, a genetic algorithm (GA) was used to design and optimize a pipe-crawling robot for parameters such as mass, power consumption, and joint extension to further the research of the Miniature Inspection Systems Technology (MIST) team. In an attempt to improve on existing designs, a new robot was developed, the piezo robot. The final proposed design uses piezoelectric expansion actuators to move the robot with a ‘ chimneying’ method employed by mountain climbers and greatly improves on previous designs in load bearing ability, pipe traversing specifications, and field usability. This research shows the advantages of GA assisted design in the field of robotics.
Uptake of Aluminum, Cadmium, Copper, Lead, and Zinc by Human Scalp Hair and Elution of the Adsorbed Metals (1989)

Uptake of aluminum (Al), cadmium (Cd), copper (Cu), lead (Pb), and zinc (Zn) from aqueous solutions by human scalp hair (water/hair = 100:1) has been studied in the concentration range 0-50 mg/L. Hair metal levels were determined by a wet digestion procedure and atomic absorption spectrometry. Under conditions used, uptake followed a sigmoid concentration-response relationship. The order of binding capacity of hair to the metals was as follows: Al greater than Cd greater than Cu greater than Pb greater than Zn. Using logit transformation 50% saturation was evaluated at the following metal concentrations (hair metal concentration of saturation is given in parenthesis): 0.34 mg/L for Al (0.154 mg/g); 1.82 mg/L for Cd (0.363 mg/g); 2.21 mg/L for Cu (0.651 mg/g); 2.52 mg/L for Pb (0.986 mg/g); 23.84 mg/L for Zn (1.616 mg/g). Percentage elution of trace metals from hair after treatment with metal-enriched solutions by five different procedures ranged from 14.5 to 46.5% for Al, from 11.1 to 28.9% for Zn, from 11.5 to 28.4% for Pb, from 8.9 to 13.6% for Cd, and from 0.1 to 11.8% for Cu. In addition, trace element concentrations were measured in tap water samples and shampoos.
Bioinformatic analysis of gene regulation in the metal-reducing bacterial family Geobacteraceae (2010)

Background Knowledge of how structural genome differences among microorganisms lead to variation in gene regulation is fundamentally important for our understanding of the functioning of gene regulatory pathways and their individual components. This knowledge is also necessary for our better understanding of the genomic changes leading to adaptation to diverse and changing environments. Our research focuses on Geobacteraceae, a metal-reducing family of delta-Proteobacteria, which are capable of harvesting electricity from organic matter and environmental bioremediation of organic and metal pollutants. We are investigating molecular mechanisms which allow these species to adapt and regulate their responses to environmental stimuli, which result in energy production and removal of environmental pollutants. Materials and methods In this presentation, we describe computational analysis of gene regulation in multiple species from this family. Our ongoing analyses include cataloguing and integrating information about gene regulation, in silico prediction of transcription factor binding sites, and investigation of functional effects of genome-scale and single nucleotide and amino acid level changes in transcription factors, operons, and regulatory sequence elements in Geobacteraceae. Specifically, we discuss our computational pipeline for comparative analyses of variation in regulatory organization among species and strains of Geobacteraceae, which allows us to investigate changes in operon organization and to track the effects of operon rearrangements and individual single nucleotide base pair level changes on regulatory sequence elements. We also describe our computational analyses of two systems of gene expression, one of gene regulation by the PilR enhancer binding protein and another by the TetR family of transcriptional regulators. Finally, we describe our ongoing efforts to catalog available information on gene regulation and operon organization of Geobacter sulfurreducens, a model representative of the Geobacteraceae family.
Multiphysics and multicriteria global optimization strategy for a series-parallel hybrid electric powertrain (2011)

The paper describes an approach to achieve the overall optimization of a series-parallel hybrid electric powertrain taking all components into account. This optimization will be based on multi-criteria such as the weight, the losses, etc; multi-constraints such as geometric constraints, electrical constraints, etc; multi-physics modeling such as mechanical parameters, electrical parameters, magnetic parameters, etc. This optimization strategy enables to carry out simultaneously each powertrain component sizing, considering global constraints. The two originalities of this paper are the modeling of the Ravigneaux gear and the systemic optimization.
Molecular prognostic testing in uveal melanoma (2007)

Uveal melanoma is the most common primary intraocular malignancy and it has a strong propensity for hematogenous metastasis to the liver and elsewhere. Despite substantial improvements in the diagnosis and treatment of the primary tumor over the past 50 years, there has not been a concomitant improvement in survival, indicating that our understanding of this cancer is still incomplete. Recently, however, research into the molecular pathobiology of uveal melanoma has provided new insights that may explain these clinical shortcomings and will soon usher in a new era of clinical management that promises to improve patient outcomes. Indeed, recent research has made uveal melanoma a model cancer for the concept of individualized, information-driven clinical decision-making based on predictive risk assessment and pre-emptive therapy. This article summarizes current clinical management of uveal melanoma and its limitations, describes traditional clinical and histopathological prognostic factors and presents a new molecular prognostic approach that could have important implications for future clinical management.
The New Hybrid Library. Audiovisual and Digital Resources. (2007)

The aim is to present how audiovisuals, a resource that contains digital components can be catalogued, indexed and preserved. Nowadays, the development of the internet has rapidly increased the volume of artistic literature and the exchange of information. But information is volatile and we must find a way to incorporate this information into our libraries. We argue that a computerized catalogue is the best instrument as well as the traditional work of the librarian, in cataloguing and indexing continue to be vital to incorporate this information always paying attention to the international cataloguing regulation and the exchange of information like the new format MARC 21. In the target T856 it allows us to establish links with websites, with digital information that we have stored in our computer if we consider it to be relevant and can complete our bibliographic resources. If computerization converted the libraries into centres of documentation, digital information should convert them into centres for internet surfing in such a way that together with the printed collection it completes and integrates a block of information and makes up the so-called hybrid library.
The Essex-Lopresti lesion (2012)

The Essex-Lopresti lesion represents a severe injury of the forearm unit. In the 1940s, it's pathology and consequences have already been mentioned by several authors. Over the course of time, the pathophysiology of the lesion was displayed in more detail. Therefore, an intensive analysis of the involved anatomic structures was done. The interosseous membrane was shown to play a major role in stabilising the forearm unit, in the situation of a fractured radial head, which is the primary stabiliser of the longitudinal forearm stability. Moreover, biomechanical analyses showed a relevant attribution of the distal radio-ulnar joint to the forearm stability. If, in the case of a full-blown Essex-Lopresti lesion, the radial head, the interosseous membrane and the distal radio-ulnar joint are injured, proximalisation of the radius will take place and will come along with secondary symptoms at the elbow joint and the wrist. According to actual studies, the lesion seems to occur more often than realised up to now. Thus, to avoid missing the complex injury, subtle clinical diagnosis combined with adequate imaging has to be undertaken. If the lesion is confirmed, several operative treatment options are available, yet not proofed to be sufficient.
Studies on Dimethoxyphenylaminoalcohols. II. Syntheses and Relative Configulations of 1-Dimethoxyphenyl-3-(alkylamino) butanols (1974)

1-Dimethoxyphenyl-3-(alkylamino) butanols were synthesized by the reduction of the corresponding β-aminoketones. 1-Dimethoxyphenyl-3-aminobutanols were synthesized via the hydrogenolyses of the corresponding N-benzyl derivatives. Diastereomers were respectively isolated and their relative configurations were determined by extensive nuclear magnetic resonance studies.
Dynamics of Network Connectivity in Urban Vehicular Networks (2011)

Vehicular ad hoc networks (VANETs) have emerged as a serious and promising candidate for providing ubiquitous communications both in urban and highway scenarios. Consequently, nowadays it is widely believed that VANETs will be able to support both safety and non-safety applications. For both classes of applications, since a zero-infrastructure is the typical premise assumed, it is crucial to understand the dynamics of network connectivity when one operates without relying on any telecommunications infrastructure. Using the key metrics of interest (such as link duration, connection duration, and re-healing time) we provide a comprehensive framework for network connectivity of urban VANETs. Our study, in addition to extensive simulations based on a new Cellular Automata Model for mobility, also provides a comprehensive analytical framework. This analytical framework leads to closed form results which facilitate physical insight into the impact of key system parameters on network connectivity. The predictions of our analytical framework also shed light on which type of safety and non-safety applications can be supported by urban VANETs.
Supplementary Data from Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets (2023)

&lt;p&gt;1 supplementary method, 3 supplementary tables and 7 supplementary figures&lt;/p&gt;
The Tate pairing and the discrete logarithm applied to elliptic curve cryptosystems (1999)

The Tate pairing is used to reduce the discrete logarithm (DL) problem on certain elliptic curves to the DL in the multiplicative group of finite fields.
Kritik über TEUCHERT, Hermann, Reinhold Olesch & Ludwig Erich Schmitt (1972) Die Sprachreste der niederländischen Siedlungen des 12. Jahrhunderts (1979)

Preview this article: Kritik über TEUCHERT, Hermann, Reinhold Olesch & Ludwig Erich Schmitt (1972) Die Sprachreste der niederländischen Siedlungen des 12. Jahrhunderts, Page 1 of 1 < Previous page | Next page > /docserver/preview/fulltext/itl.44.06ker-1.gif
Video Laryngoscopic Techniques Associated with Intubation Success in a Helicopter Emergency Medical Service System (2016)

Bodily fluids obstructing the view, equipment problems, higher Cormack-Lehane view, and longer ETI attempt time were negatively associated with successful ETI attempts. Initially shallow blade tip position may associate with longer ETI time. VL is useful for measuring and describing multiple factors of ETI and can provide valuable data.