gebhart/patrepeval huggingface dataset:
Peripheral pulmonary stenosis with Noonan syndrome treated by balloon pulmonary angioplasty (2020)

Noonan syndrome is known to have various cardiovascular defects, which include pulmonary artery stenosis. Pulmonary artery stenosis is characterized by obstruction of pulmonary artery blood flow that can cause elevated pulmonary artery pressure and ventilation-perfusion inequality, which can cause dyspnea on exertion and eventually, heart failure. Although the etiology of pulmonary artery stenosis related to congenital diseases is still unknown, balloon pulmonary angioplasty has being reported to be effective to selected patients with Alagille and Williams syndromes, but not from Noonan syndrome despite of modest prevalence of pulmonary artery stenosis. Here, we report the first Noonan syndrome patient with pulmonary artery stenosis who underwent successful balloon pulmonary angioplasty. The strategy used in balloon pulmonary angioplasty was planned with careful morphologic evaluation by computed tomographic angiography, and performed with scoring balloons in a graded approach with multiple sessions. After balloon pulmonary angioplasty, we confirmed maintained dilation of lesions and symptom alleviation, suggesting that balloon pulmonary angioplasty can be performed safely on pulmonary artery stenosis in a Noonan syndrome patient.
Interacting with Objects in Games Through RFID Technology (2013)

Interactive games aimed at educational environments are becoming increasingly important in children s learning. At the same time, technological advances are definitely causing the arrival of new computational paradigms, such as Ubiquitous Computing or Internet of Things. Ubiquitous Computing was defined by Mark Weiser in 1988, which provides the user with advanced and implicit computing, capable of carrying out a set of services of which the user is not aware. Internet of Things is similar to the Ubiquitous Computing para‐ digm and was introduced by Kevin Ashton in 1999 [7]. The scenario is described as a daily life object network where all of the objects are digitalized and interconnected.
Photoelectric Recording Interferometer for Gas Analysis (1959)

A photoelectric recording interferometer for gas analysis is reported. Central part of interference fringes is projected on the single slit of a photomultiplier through a polarizer P1 with its principal axis perpendicular to fringes and a field splitting polarizer P2 whose two Polaroid planes are split by a line parallel to fringes and oriented to ±45° to the principal axis of the polarizer P1 and a rotating Polaroid disk. When the center of a fringe is brought in line with the splitting line of polarizer P2, alternating photocurrent becomes zero. Any change of position of the center line of the fringe relative to the splitting line generates an alternating photocurrent with an amplitude which is a function of the fringe shift and a phase which is a function of the direction of the shift. The shift of fringes which is proportional to gas concentration is detected; this shift makes a servo-motor start to put the fringes back to their original position optically. The angle of rotation of the servo-motor is proportional to the shift of fringes indicating the variation of the refractive index, i.e., the variation of the content ratio of the mixed gas. The sensitivity of this apparatus is observed to be about 1×10−8 index unit, or in the case of CO2 gas in air, about 0.01% by volume.
Recent Advances In The Synthesis And Characterization Of New Nonlinear Optical Polymers (1990)

Electron nuclear double resonance studies and theoretical calculations suggest that self-localization occurs in coupled π-electron systems. Since intrinsic (electron-phonon and electron coulombic) interactions determine the extent of electron delocalization (hence derivative properties such as optical nonlinearity), it is not necessary to synthesize polymers possessing long segments of uninterrupted π conjugation. Thus, we have investigated the synthesis of copolymers containing alternating saturated and unsaturated segments. The number of advantages realized with this approach include improved solubility (which translates into improved processibility), higher polymer molecular weights (which translates into films of improved mechanical strength) for polycondensation synthetic procedures and sharper bandedges (bandedge tailing due to a distribution of short polymer lengths is avoided). This last feature results in better discrimination of resonant and non-resonant contributions to third order susceptibility. Finally, we discuss the extension of our development program for nonlinear optical materials to the preparation of organometallic as well as organic materials and the extension to the preparation of composite materials as well as homo and copolymer systems.
Mutations in the hereditary haemochromatosis gene HFE in professional endurance athletes (2004)

The findings support the need to assess regularly iron stores in elite endurance athletes.
239 PuO 2 Aerosol Inhalation Exposure of Miniature Swine (1978)

M. T. Karagianes, J. L. Beamer, A. J. Clary, D. K. Craig, J. R. Decker, W. C. Cannon, 239 PuO2 Aerosol Inhalation Exposure of Miniature Swine, Radiation Research, Vol. 74, No. 1 (Apr., 1978), pp. 79-87
Multiferroic properties and dielectric relaxation of BiFeO3∕Bi3.25La0.75Ti3O12 double-layered thin films (2007)

Bi Fe O 3 (BFO)∕Bi3.25La0.75Ti3O12 (BLT) films were prepared on (111) Pt∕Ti∕SiO2∕Si substrates via metal organic decomposition method. The multiferroic and dielectric properties of the films were studied. It was found that the ferroelectric polarization and dielectric constant of the films were enhanced by introducing BLT as a barrier layer between BFO and Pt bottom electrode, while the ferromagnetism of BFO was not influenced. More interestingly, the films showed dielectric relaxor behavior, and the possible causes of which were discussed.
Dynamic imaging of pharmacokinetics with Sparse Spectral Sampling Stimulated Raman Scattering (S4RS) hyperspectral microscopy (2022)

Stimulated Raman Scattering (SRS) is a powerful method for quantifying the uptake, flow, and flux of active pharmaceutical ingredients (APIs). While there are numerous APIs that have unique structures and vibrational spectra, the majority do not have strong or unique vibrational bands. We have developed a sparse spectral sampling SRS imaging system to address these needs that can rapidly and specifically tune into specific Raman shifts from the fingerprint to high wavenumber region in < 5 ms per step. These hyperspectral SRS images can be analyzed using computational analytical approaches to visualize and quantify the dynamics of multiple molecular species simultaneously.
Hypergraphs for Joint Multi-view Reconstruction and Multi-object Tracking (2013)

We generalize the network flow formulation for multiobject tracking to multi-camera setups. In the past, reconstruction of multi-camera data was done as a separate extension. In this work, we present a combined maximum a posteriori (MAP) formulation, which jointly models multicamera reconstruction as well as global temporal data association. A flow graph is constructed, which tracks objects in 3D world space. The multi-camera reconstruction can be efficiently incorporated as additional constraints on the flow graph without making the graph unnecessarily large. The final graph is efficiently solved using binary linear programming. On the PETS 2009 dataset we achieve results that significantly exceed the current state of the art.
Effects of chronic administration of selective betablockers on peripheral circulation of the lower limbs in patients with essential hypertension. (1986)

This paper summarizes the results of two studies carried out to evaluate the effects of the cardioselective betablockers atenolol, acebutolol and metoprolol on peripheral circulation of the lower limbs. The 1st study was a double dummy double blind cross over placebo controlled trial carried out for 13 weeks to evaluate the effects of acebutolol (600 mg/die) and metoprolol (300 mg/die), two cardioselective betablockers, on peripheral haemodynamics in patients suffering from mild to moderate hypertension. The 2nd study was a placebo controlled trial on the effects of atenolol (100 mg/day) on haemodynamics at the calf carried out for 8 weeks in patients suffering from essential to severe moderate hypertension, part of which aged over 65 years and affected by arteriosclerosis obliterans of the lower limbs, stage I and II according to Fontaine's classification. Calf blood flow in basal condition (R.F.) and after ischemic stimulus (P.F.) was evaluated by strain gauge plethysmography; basal (B.V.R.) and minimal (M.V.R.) vascular resistances at the calf by the ratio between M.B.P./R.F. and M.B.P./P.F. respectively, Windsor's index (W.I.) by ultrasound. Neither the patients with hypertension only nor the elderly hypertensive suffering from arteriosclerosis obliterans of the lower limbs showed changes in R.F. and P.F., in B.V.R. and M.V.R. and in W.I. after chronic treatment with cardioselective beta-blockers. Many patients--about 17% of all patients, and 40% of arteriopathics--in the two trials had cold hands and feet. These studies suggest that chronic administration of selective beta-blockers does not exert unfavourable effects on muscular blood flow at the calf in patients with hypertension with or without arteriosclerosis obliterans of the lower limbs at I and II stage.(ABSTRACT TRUNCATED AT 250 WORDS)
Experimental human muscle pain induced by intramuscular injections of bradykinin, serotonin, and substance P (1999)

After intramuscular (m. tibialis anterior) injection of three different algogenic substances, the pain intensity was continuously scored on a visual analogue scale (VAS) in eight volunteers. The subject drew the distribution of the local and referred pain areas on a map. Four times within the first hour after injection, the pressure pain-thresholds (PPTs) and supra pressure-pain thresholds were assessed at the injection point, 2 cm distal from the injection site, at the arm, and at the contralateral leg. Measurements were done before and after injection of 0.5 ml of the algogenic substance [bradykinin (BKN), serotonin (5-HT), substance P (SP)], and isotonic saline as control. Cutaneous sensitivity to mechanical stimuli was assessed with a Von Frey hair at the same location as PPT determinations.The pain intensity (VAS-peak) after BKN (2, 4, and 10 nmol) and 5-HT (2, 4, and 20 nmol) was significantly higher (p< 0.05) than after SP (0.2, 0.4, and 0.8 nmol) and isotonic saline. The VAS-peak after infusions of hypertonic saline was significantly higher (p< 0.05) compared with VAS-peaks after all other substances. A significantly larger (p< 0.05) local pain area was found after BKN compared with isotonic saline. After injections of hypertonic saline, the offsets of evoked pain were significantly longer (p< 0.05) and the local and referred pain areas were significantly larger (p< 0.05) compared with all other substances. There was no dose-response relation between the pain intensity and the different doses of BKN, 5-HT, and SP. PPTs and skin sensitivity were not affected by any of the injections.We conclude that under the present experimental conditions, BKN and 5-HT can produce low levels of muscle pain after intramuscular injection. In the used concentrations, however, BKN, 5-HT, and SP did not generate cutaneous or muscular hyperalgesia. Copyright 1999 European Federation of Chapters of the International Association for the Study of Pain.
IMPACT OF 50, 55 OR 60 M.P.H. STATEWIDE SPEED LIMIT (1974)

This analysis was completed in order to determine the probable impact that a statewide speed limit might have on gasoline consumption in the state of Michigan. For the purposes of this study it was assumed that the most likely speed limit would be 50 M. P. H. Additional analyses were also completed for both a 55 M.P.H. speed limit and also a 60 M.P.H. speed limit. Three basic data sources were used to complete this analysis. They were: (1) 1972 U. S. Department of Transportation Table T. A. 1 for Michigan; (2) textbook by Robley Winfrey entitled Economic Analysis for Highways; and (3) Michigan Department of State Highways and Transportation Report #66 entitled Speed Report, April, 1972. Analysis completed in this document is intended solely as an initial inquiry. The results obtained are based upon several judgemental assumptions and use of this information must be based upon full knowledge of these assumptions.
Influence of Coulomb Blockade on Wave Packet Dynamics in Nanoscale Structures (2013)

Influence of Coulomb blockade on electron scattering by a quantum dot has been theoretically investigated using a multielectron wave packet simulation technique based on the time-dependent Hartree–Fock approximation. In our simulation, the bound states of electrons in the dot are self-consistently determined. We confirmed that Koopman's theorem keeps its validity only for weak Coulomb interactions. Moreover, we show that the maximum number of electrons trapped in the dot does depend on the strength of Coulomb interactions. Consequently, the transmission and reflection probabilities of an incident wave packet toward the dot are strongly influenced by the number of trapped electrons in the dot.
Fruit Quality Evaluation Using Spectroscopy Technology: A Review (2015)

An overview is presented with regard to applications of visible and near infrared (Vis/NIR) spectroscopy, multispectral imaging and hyperspectral imaging techniques for quality attributes measurement and variety discrimination of various fruit species, i.e., apple, orange, kiwifruit, peach, grape, strawberry, grape, jujube, banana, mango and others. Some commonly utilized chemometrics including pretreatment methods, variable selection methods, discriminant methods and calibration methods are briefly introduced. The comprehensive review of applications, which concentrates primarily on Vis/NIR spectroscopy, are arranged according to fruit species. Most of the applications are focused on variety discrimination or the measurement of soluble solids content (SSC), acidity and firmness, but also some measurements involving dry matter, vitamin C, polyphenols and pigments have been reported. The feasibility of different spectral modes, i.e., reflectance, interactance and transmittance, are discussed. Optimal variable selection methods and calibration methods for measuring different attributes of different fruit species are addressed. Special attention is paid to sample preparation and the influence of the environment. Areas where further investigation is needed and problems concerning model robustness and model transfer are identified.
Synthesis and Characterization of Superoxide Dismutase-Deferoxamine Conjugate via Polyoxyethylene. A New Molecular Device for Removal of a Variety of Reactive Oxygen Species (1995)

A conjugate of Cu,Zn-superoxide dismutase (SOD) with a strong iron chelating agent, deferoxamine (DFO), was synthesized (SOD-POE-DFO) via polyoxyethylene (POE) as a linking agent. N-terminal amino groups of lysine residues in SOD are modified with 1:1 binding products of polyoxyethylene and deferoxamine (POE-DFO) through a covalent amido bond. The mean number of the POE-DFO bound per one SOD molecule is calculated to be 3.3 by determining the C/N ratio after elemental analysis. The half-life of the SOD-POE-DFO is about 1.2 h in rats, whereas that of free SOD is about 5-10 min. POE plays the part not only of the linking agent but also of expanding the lifetime in the circulation. The SOD-POE-DFO possesses both the metal chelating ability (for DFO) and the ability of scavenging superoxide radicals (for SOD). Therefore, the SOD-POE-DFO of the present study can eliminate the superoxide radical and free iron simultaneously and in the same location, and thus, it would be a molecular device with multiple functions which prevents the damage to tissues by scavenging the variety of reactive oxygen species.
A Defects Detection System for Substation Based on YOLOX (2022)

To improve the intelligent supervision level of substation, a defects images dataset facing to substation scenario was built by collecting and labeling a huge number of images about substation equipment defects. Then a transfer learning model based on the YOLOX model was trained by adjusting the model training parameters. Finally, a model with 87.4 % mean average precision and affordable speed (about 0.07 second per image) was constructed. And the experiments results proved that this model can detect the preset defects of substation equipment accurately in acceptable speed according to the visible image obtained from monitoring equipment, which means it has satisfying application potential in future.
Aeroacoustic Importance of Installation Effects for Non-Periodic Open Rotor Noise Emission (2012)

Fibromatosis is a rare fibroproliferative disorder with a tendency for local infiltrative and destructive growth. Local recurrence is frequent, despite apparent complete resection after radical excision. We present a case of a 22-year-old woman with massive recurrent thoracic fibromatosis extending into the neck and impairing the function of her right upper limb. This required a multidisciplinary approach to surgery to salvage the limb. The case highlights the fact that while every attempt should be made to achieve negative histologic margins, local recurrence is not uncommon. Therefore, if fibromatosis occurs adjacent to or involves vital structures, these should not be sacrificed to achieve negative margins. Function and structure preserving procedures are important as the primary goal, if not even more important.
Mediators of the resistance and aerobic exercise intervention effect on physical and general health in men undergoing androgen deprivation therapy for prostate cancer (2013)

The intervention effects on physical and general health were explained by different mediating mechanisms. Walking speed mediated the intervention effect on both physical and general health. The intervention effect on physical health was further mediated by upper body strength, whereas the effect on general health was mediated by fatigue.
An Optical 6-Axis Force Sensor for Brain Function Analysis using fMRI (2004)

This paper presents an 6-axis optical force sensor which can be used in fMRI. Recently, fMRI are widely used for studying human brain function. Simultaneous measurement of brain activity and peripheral information, such as grip force, enables more precise investigations in studies of motor function. However, conventional force sensors cannot be used in fMRI environment, since metal elements generate noise which severely contaminate the signals of fMRI. An optical 2-axis force sensor has been developed using photo sensors and optical fibers by Tada et al., that resolved these problems. The developed force sensor removed all magnetic components from the sensing part. It detected minute displacements by measure amount of light and light traveled through the optical fibers. However, there still remain several problems on this optical force sensor. Firstly, the accuracy is not high compared to the conventional force sensors. Secondly, the robustness is not enough against the contact force to the optical fibers. In this paper, the problems concerning to the acturacy and the sensor output stability has been improved by novel methods of fixing fibers and arithmetic circuit. An optical 6-axis force is developed based on these improvements, and usefulness of our sensor for brain function analysis is confirmed in fMRI experimentations.
Estimating the dimensionality of neural responses with fMRI Repetition Suppression (2016)

We propose a novel method that exploits fMRI Repetition Suppression (RS-fMRI) to measure the dimensionality of the set response vectors, i.e. the dimension of the space of linear combinations of neural population activity patterns in response to specific task conditions. RS-fMRI measures the overlap between response vectors even in brain areas displaying no discernible average differential BOLD signal. We show how this property can be used to estimate the neural response dimensionality in areas lacking macroscopic spatial patterning. The importance of dimensionality derives from how it relates to a neural circuit's functionality. As we show, the dimensionality of the response vectors is predicted to be high in areas involved in multi-stream integration, while it is low in areas where inputs from independent sources do not interact or merely overlap linearly. Our method can be used to identify and functionally characterize cortical circuits that integrate multiple independent information pathways.
Cytotoxicity of glutaraldehyde crosslinked collagen/poly(vinyl alcohol) films is by the mechanism of apoptosis (2002)

Collagen has been investigated as a potential natural biomaterial, because of its occurrence in the extracellular matrix. Collagen requires crosslinking in this context, by reagents that are often cytotoxic. Glutaraldehyde is one such agent that is potentially cytotoxic. The aim of this study was to determine the cause of poor cell attachment and growth on collagen/poly(vinyl alcohol) bioartificial composite films, when crosslinked with glutaraldehyde. Dehydrothermal crosslinking was used as a comparison. Human osteoblasts were observed to undergo apoptosis on glutaraldehyde crosslinked films dependent on concentration of collagen present. Higher collagen content resulted in higher levels of apoptosis with poor cell attachment and spreading of remaining cells. Post-treatment of films with 8% L-glutamic acid prevented the apoptotic response of osteoblasts and allowed attachment and spreading. The addition of 100 nM insulin-like growth factor-1 to the culture medium also prevented apoptosis. Glutaraldehyde toxicity of crosslinked collagen has been demonstrated in this study, the mechanism of which is apoptosis. This study indicates that poor biocompatibility and induction of apoptosis on collagen/poly(vinyl alcohol) films crosslinked by glutaraldehyde are attributed to glutaraldehyde components on the surface of the films (not residual glutaraldehyde), whose effects can be quenched by glutamic acid, and prevented by insulin-like growth factor-1. © 2002 Wiley Periodicals, Inc. J Biomed Mater Res 61: 121–130, 2002
Multiple maskers for speech masking in open-plan offices (2012)

Sound masking is an effective method to reduce speech intelligibility for reaching acceptable speech privacy in open-plan offices. Speech-like masker is considered as a good choice to reduce speech intelligibility. Using one masker in masking system is the common way so far. In this paper, a new method was proposed, using randomly integrated speech frames (SF) of the speaker as masker. Because SF masker was based on speech of the same speaker, it is a good speech-like masker. We further studied the method of using multiple SF maskers. The performance of this new masking method was evaluated by objective measurement (STOI). The speech masked by one SF masker and multiple SF maskers were compared. Results showed that speech with SF masker could reduce speech intelligibility. Speech with multiple SF maskers led to poorer speech intelligibility than speech with only one SF masker. Masking speech by multiple SF maskers is an effective way to reduce speech intelligibility in open-plan offices. (Acknowledgement: This research was supported by the joint training PhD program of Chinese Academy of Sciences-Fraunhofer, and Fraunhofer Institute of Building Physics in Stuttgart, Germany.)
Heterosupramolecular Chemistry:  Self-Assembly of an Electron Donor (TiO2 Nanocrystallite)−Acceptor (Viologen) Complex (1997)

A TiO2 nanocrystallite has been modified to selectively bind, by complementary hydrogen bonding, a uracil substrate incorporating a viologen moiety. Bandgap excitation of the self-assembled donor (TiO2 nanocrystallite)−acceptor (viologen) complex results in electron transfer. Some implications of these findings for the self-assembly of functional nanostructures containing both condensed phase and molecular components are considered.