gebhart/patrepeval huggingface dataset:
Classification of Recorded Musical Instruments Sounds Based on Neural Networks (2007)

Neural networks have found profound success in the area of pattern recognition. The purpose of this paper is to classify automatically musical instrument sounds on the basis of a limited number of parameters. And this involves issues like feature extraction and development of classifier using the obtained features. As for feature extraction, a 5 second audio file stored in WAVE format is passed to a feature extraction function. The feature extraction function calculates more than 20 numerical features both in time-domain and frequency-domain that characterize the sample. Regarding the task of classification, we designed a two-layer feed-forward neural network (FFNN) using back-propagation training algorithm. The FFNN is trained in a supervised manner - the weights are adjusted based on training samples (input-output pairs) that guide the optimization procedure towards an optimum. After training, the neural network is validated by analyzing its response to unknown data in order to evaluate its generalization capabilities. Then, the sequential forward selection method is adopted to choose the best feature set to achieve high classification accuracy. Our goal is mainly to classify the sound into five different musical instrument families, such as the Strings, the Woodwinds and the Brass
Epitaxial growth by low pressure chemical vapour deposition of Si/sub 1-x/Ge/sub x//Si and applications (2002)

Low pressure chemical vapour deposition of Si and SiGe was investigated for novel devices for microelectronics and optoelectronics. Results on facet formation, nanostructures by lateral confinement with facets, increase of the critical thickness in finite pads, 2D to 3D growth transition and application to light emitting diodes with room temperature operation will be presented.
Development of oxide inclusions during vacuum degassing process (2012)

This article sets out to study the development of oxide inclusions during the vacuum degassing process at the ASEA-SKF ladle furnace. During the degassing process, five steel and top slag samples were taken, and their chemical compositions were analysed. All steel samples were further analysed by scanning electron microscopy. It was concluded that the vacuum degassing process was a dynamic process during which spinel and calcium aluminate inclusions were dominant. In addition, it was seen that during this process, the percentage share of calcium aluminates compared with spinels, the Ca weight per cent content of the oxides, the average equivalent circle diameter (ECD) of the oxides and the percentage share of the oxides with bigger ECD were increasing, and the oxides tended to form more round shapes.
Parallel processing architectures for iterative image restoration (2003)

Mesh and mesh-of-pyramids implementations of iterative image restoration algorithms are proposed. These implementations are based on a single-step algorithm as well as on a multistep iterative algorithm derived from the single step regularized iterative restoration algorithm. One processor is assigned to each picture element, with local memory depending on the support of the restoration filter. The implementations consist of interprocessor communication and intraprocessor computations. The efficiency of the proposed VLSI algorithms is judged by establishing lower bounds on AT/sup 2/, where A is the area of the VLSI and T is its computation time.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Electrophoretic mobility distributions distinguish hairy cells from other mononuclear blood cells and provide evidence for the heterogeneity of normal monocytes (1981)

The electrophoretic mobility distributions of hairy cells, normal monocytes. CLL, and normal lymphocytes isolated from blood were determined by electrophoretic light scattering. Values obtained for hairy cells, 1.52 X 10(-4) cm2/V . sec, were indistinguishable from that of normal monocytes. The mobility of CLL lymphocytes was similar to that of normal B cells. After exposure to neuraminidase, hairy cells revealed a homogeneous distribution with a reduced mobility of 0.55 X 10(-4) cm2/V . sec, while normal monocytes showed a heterogeneous distribution of electrophoretic mobilities suggestive of subpopulations. The electrokinetic behavior of hairy cells thus differs from that or normal and CLL lymphocytes before, and from that of monocytes after, treatment with neuraminidase. The hairy cell therefore possesses a distinct pattern of surface charge properties that clearly distinguish it from the circulating B cells, T cells, or monocytes.
Phase-Based Profiling in GPGPU Kernels (2012)

More and more computationally intensive scientific applications make use of hardware accelerators like general purpose graphics processing units (GPGPUs). Compared to software development for typical multi-core processors their programming is fairly complex and needs hardware specific optimizations to utilize the full computing power. To achieve high performance, critical parts of a program have to be identified and optimized. This paper proposes an approach for performance analysis of CUDA kernel source code regions, which for the first time allows measuring the execution times within GPGPU kernels. We developed a tool, which implements the presented method and supports the application developer to easily identify hot spots within the kernel. The presented tool uses compile time code analysis to automatically instrument suitable instrumentation points for minimal program perturbation and further provides support for manual instrumentation. To the best of our knowledge this is the first approach, which allows for scalable runtime analysis within GPGPU kernels. Combined with existing performance analysis techniques this facilitates obtaining the full potential of modern parallel systems.
Compiling More Precise Petri Net Models for an Improved Verification of Service Implementations (2014)

Verification of distributed business processes typically relies on Petri-net-based process models, which allow for a natural modeling and analysis of aspects like parallelism and message exchange. Unfortunately, such a process model is seldom complete and precise today, mainly because the available techniques for its derivation neglect process data in favor of a feasible verification. In this paper, we present an approach for deriving more precise process models in terms of a transforming process-to-Petri-net compiler, which takes as input a business process and generates as output a Petri net model for the process which can subsequently be used for verification. However, in contrast to a conventional compiler, its objective is not to result in efficient runtime code but rather to produce a most-precise though still effectively verifiable Petri-net-based process model.
Robust Point Set Registration Using Gaussian Mixture Models (2010)

In this paper, we present a unified framework for the rigid and nonrigid point set registration problem in the presence of significant amounts of noise and outliers. The key idea of this registration framework is to represent the input point sets using Gaussian mixture models. Then, the problem of point set registration is reformulated as the problem of aligning two Gaussian mixtures such that a statistical discrepancy measure between the two corresponding mixtures is minimized. We show that the popular iterative closest point (ICP) method and several existing point set registration methods in the field are closely related and can be reinterpreted meaningfully in our general framework. Our instantiation of this general framework is based on the the L2 distance between two Gaussian mixtures, which has the closed-form expression and in turn leads to a computationally efficient registration algorithm. The resulting registration algorithm exhibits inherent statistical robustness, has an intuitive interpretation, and is simple to implement. We also provide theoretical and experimental comparisons with other robust methods for point set registration.
AN ECONOMIC STUDY OF THE PRODUCTION OF AMMONIA USING ELECTRICITY FROM A NUCLEAR DESALINATION REACTOR COMPLEX (1966)

This report was prepared as an account of Governmen t sponsored work.Neither the United States, nor the Commissio n, nor any person acting on behalf of the Commissio n:A. Makes any warranty or representat ion, expressed or implied, with respect to the accu racy, completene ss, or usefulness of the information contained in this report, or that the use of any information , apparatus, method, or process disclosed in this report may not infringe privately owned rights; or B. Assumes any liabilities with respect to the use of, or for damages resulting from the use of any information , apparatus, method, or process disclosed in this report.As used in the above, "person acting on behalf of the Commissio n" includes any em ployee or contractor of the Commissio n, or employee of such contractor, to the extent that such employee or contractor of the Commissio n, or employee of such contractor prepares, disseminat es, or provides access to, any information pursuant to his employmen t or contract with the Commissio n, or his employmen t with such contractor.
Pollen-derived nonallergenic substances enhance Th2-induced IgE production in B cells (2015)

Aqueous pollen extracts, the protein-free fraction of Amb-APE, and the pollen-contained substance PPE1 specifically enhance IgE production in Th2-primed B cells. Thus, pollen-derived nonallergenic substances might be responsible for B-cell-dependent aggravation of IgE-mediated allergies.
Kinetic and Theoretical Studies of a Facile, One‐Pot Preparation of a Spirocyclohexylindolinone Derivative (2006)

Abstract Spirocyclohexylindolinone is used as a moiety in drug substances. A number of synthetic methods have been suggested to introduce the cyclohexyl ring into the C(3) position of N ‐protected indolinones, which complicates their preparation. A previously developed, consecutive, one‐pot, multicomponent method is studied from a mechanistic aspect. We set out to clarify the details of this mechanism and the role of the acryl ester as a reagent and a protecting group in the same flask, by using theoretical and analytical methods, in order to optimise the preparative conditions. A mechanistic energy profile of the reaction is computed at the DFT level of theory. (© Wiley‐VCH Verlag GmbH &amp; Co. KGaA, 69451 Weinheim, Germany, 2006)
Responses of the parasitoid Praon volucre (Hymenoptera: Braconidae) to aphid sex pheromone lures in cereal fields in autumn: Implications for parasitoid manipulation (1993)

Females of the aphid parasitoid Praon volucre were attracted to lures containing synthetic aphid sex pheromone components, particularly (+)-(4aS,7S,7aR)-nepetalactone, when these were placed on water traps in cereal fields in autumn. Trap catches were greatest at a site in S.W.England and fewest at sites in northern England 'and northern Germany, presumably due to climatic differences. Responses to the pheromones were not detected for any other cereal aphid parasitoids in the field trials, although Aphidius rhopalosiphi appears to possess olfactory receptors for (+)-(4aS,7S,7aR)-nepetalactone. A potential strategy for the use of aphid sex pheromone lures to manipulate aphid parasitoids in the field, in order to enhance their impact on aphid populations, is outlined.
Short-term injection of antiapoptotic cytokine combinations soon after lethal γ-irradiation promotes survival (2003)

Recovery from radiation-induced (RI) myelosuppression depends on hematopoietic stem and progenitor cell survival and the active proliferation/differentiation process, which requires early cytokine support. Single cytokine or late-acting growth factor therapy has proved to be inefficient in ensuring reconstitution after severe RI damage. This work was aimed at evaluating the in vivo survival effect of combinations of early-acting cytokines whose antiapoptotic activity has been demonstrated in vitro: stem cell factor (SCF [S]), FMS-like tyrosine kinase 3 ligand (FLT-3 ligand [F]), thrombopoietin (TPO [T]), interleukin-3 (IL-3 [3]), and stromal derived factor-1 (SDF-1). B6D2F1 mice underwent total body irradiation at 8 Gy cesium Cs 137 gamma radiation (ie, lethal dose 90% at 30 days) and were treated soon after irradiation, at 2 hours and at 24 hours, with recombinant murine cytokines, each given intraperitoneally at 50 microg/kg per injection. All treatments induced 30-day survival rates significantly higher than control (survival rate, 8.3%). 4F (SFT3) and 5F (4F + SDF-1) were the most efficient combinations (81.2% and 87.5%, respectively), which was better than 3F (SFT, 50%), TPO alone (58.3%), and SDF-1 alone (29.2%) and also better than 4F given at 10 microg/kg per injection (4F10, 45.8%) or as a 50 microg/kg single injection at 2 hours (4Fs, 62.5%). Despite delayed death occurring mainly from day 150 on and possible long-term hematopoiesis impairment, half the 30-day protective effects of 4F and 5F were preserved at 300 days. Our results show that short- and long-term survival after irradiation depends on appropriate multiple cytokine combinations and at optimal concentrations. The proposal is made that an emergency cytokine regimen could be applied to nuclear accident victims as part of longer cytokine treatment, cell therapy, or both.
Céramiques techniques à pispersoïdes : alumine zircone et alumine - oxynitrure d'aluminium gamma. (1987)

National audience
USING FINE GRAIN NON RIABLE LENGTH DECODER ORM TABLE PARTITIONING (2015)

Variable length coding is a widely used technique in digital video compression systems. Previous work related to variable length decoders are primarily aimed at high throughput appli-cations, but the increased demand for portable multimedia sys-tems has made power a very important factor. In this paper a data driven variable length decoding algorithm is presented, which exploits the signal statistics of variable length codes to reduce power. It uses fine grain lookup table partitioning based on coldeword frequency. An order magnitude of power reduc-tion is possible compared to conventional parallel decoding scheme with a single lookup table. 1.
Mass Spectrometric Analysis of Lewy Body-Enriched α-Synuclein in Parkinson’s Disease (2019)

Parkinson's disease (PD) is characterized by intraneuronal inclusions of aggregated α-synuclein protein (so-called Lewy bodies) in distinct brain regions. Multiple posttranslational modifications may affect the structure and function of α-synuclein. Mass spectrometry-based analysis may be useful for the characterization and quantitation of α-synuclein forms, but has proven challenging, mainly due to the insolubility of Lewy bodies in aqueous buffer. In the present study, we developed a novel method by combining differential solubilization with immunoprecipitation and targeted proteomics using liquid chromatography and tandem mass spectrometry. Brain tissue homogenization and sample preparation were modified to facilitate analysis of soluble, detergent-soluble, and detergent-insoluble protein fractions (Lewy body-enriched). The method was used to compare α-synuclein forms from cingulate cortex (affected) and occipital cortex (unaffected) in two study sets of PD patients and controls. We identified ∼20 modified α-synuclein variants, including species with N-terminal acetylation and C-terminal truncations at amino acids 103 and 119. The levels of α-synuclein forms Ac-α-syn<sub>1-6</sub>, α-syn<sub>13-21</sub>, α-syn<sub>35-43</sub>, α-syn<sub>46-58</sub>, α-syn<sub>61-80</sub>, and α-syn<sub>81-96</sub> except α-syn<sub>103-119</sub> were significantly increased in PD cingulate region compared to controls in the Lewy body-enriched α-synuclein fraction. In the soluble fraction, only Ac-α-syn<sub>1-6</sub> was significantly increased in PD compared to controls. None of the detected α-synuclein variants were Lewy body-specific, but acetylated forms should be examined further as potential biomarkers for abnormal α-synuclein accumulation.
Organozinc complexes with monoanionic chelating phenolates or 2-pyridylmethanolates. Molecular structure of [Zn(CH2SiMe3){OCH2(2-Py)}]4 (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOrganozinc complexes with monoanionic chelating phenolates or 2-pyridylmethanolates. Molecular structure of [Zn(CH2SiMe3){OCH2(2-Py)}]4Paul A. van der Schaaf, Elmo Wissing, Jaap Boersma, Wilberth J. J. Smeets, Anthony L. Spek, and Gerard van KotenCite this: Organometallics 1993, 12, 9, 3624–3629Publication Date (Print):September 1, 1993Publication History Published online1 May 2002Published inissue 1 September 1993https://doi.org/10.1021/om00033a039Request reuse permissionsArticle Views147Altmetric-Citations34LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (2 MB) Get e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Propagation of Adult Rat Bone Marrow-Derived Hepatocyte-Like Cells by Serial Passages in Vitro (2004)

Previously, we found that hepatocyte growth factor receptor (c-Met)-and alpha-fetoprotein (AFP)-expressing cells were present in adult rat bone marrow, and that these cells also expressed hematopoietic stem cell markers, such as CD34, Thy-1, and c-Kit. When bone marrow cells were cultured in a hepatocyte growth medium (HGM) with HGF and EGF, colonies composed of polygonal cells resembling mature hepatocytes appeared by 2 weeks and grew very slowly because of overgrowth of stromal cells. At days 34-41, 2-mm2 sheets of hepatocyte-like cells were cut out of their colonies by scratching with an injection needle under observation with a phase contrast microscope, transferred into wells of 24-well plates, and cultured in the HGM medium in the presence or absence of HGF and EGF. When cells reached confluence, cells were detached with trypsin and EDTA and transferred step by step into bigger culture vessels. Thus, hepatocyte-like cells were expanded 1000-fold during less than 4 months. These cells were immunocytochemically stained for albumin and also for AFP and the hematopoietic stem cell markers described above, showing characteristics of oval cells. By RT-PCR, we detected mRNAs of tryptophan-2,3-dioxygenase and tyrosine aminotransferase, markers of hepatocytes at a terminal differentiation stage. The present culture system may be useful for supply of hepatocyte resources for cell transplantation therapy.
Genistin-rich soy isoflavone extract in substrate reduction therapy for Sanfilippo syndrome: An open-label, pilot study in 10 pediatric patients (2008)

This pilot study found some improvements in GAG concentration, hair morphology, and cognitive function in these pediatric patients with Sanfilippo syndrome treated with genistin-rich soy isoflavone extract for 1 year. Clinical trials are needed to evaluate the efficacy and safety of this potential treatment.
Cholinomimetics and Memory (1980)

Young normal subjects received 16 g of choline chloride in a double-blind A-B-A design. Short- and long-term memory function was evaluated. Comparison of group means indicated that choline chloride did not significantly affect short-term memory or long-term memory. However, individual subjects may have had some aspects of long-term memory affected by choline chloride treatments. The results suggest that the effect of lower doses of choline on long-term memory should be evaluated.
The Key Role of Nucleic Acid Vaccines for One Health (2021)

The ongoing SARS-CoV-2 pandemic has highlighted both the importance of One Health, i.e., the interactions and transmission of pathogens between animals and humans, and the potential power of gene-based vaccines, specifically nucleic acid vaccines. This review will highlight key aspects of the development of plasmid DNA Nucleic Acid (NA) vaccines, which have been licensed for several veterinary uses, and tested for a number of human diseases, and will explain how an understanding of their immunological and real-world attributes are important for their efficacy, and how they helped pave the way for mRNA vaccines. The review highlights how combining efforts for vaccine development for both animals and humans is crucial for advancing new technologies and for combatting emerging diseases.
Advances in Nonlinear Rotordynamics of Passenger Vehicle Turbochargers: A Virtual Laboratory Anchored to Test Data (2005)

Passenger vehicle turbochargers (TCs) offer increased IC engine power and efficiency. TCs operate at high rotational speeds and use engine oil in their bearing support system comprising of inner and outer lubricant films acting in series. The hydrodynamic bearings induce instabilities, i.e. subsynchronous shaft motions over wide operating speed ranges [1]. Yet, the motions are well bounded limit enabling the TC continuous operation [2, 3]. Due to the lack of accurate and efficient predictive nonlinear tools, turbocharger rotordynamic design followed, until recently, costly test stand iteration [3]. Presently, a rotordynamics model coupled to a bearing lubrication model calculates the nonlinear motions of TCs and delivers predictions of TC shaft dynamic response for practical conditions [4–6]. The software emulates a virtual laboratory, effectively aiding to design better TC products with increased reliability in a shorter cycle time. Predictions of the nonlinear model compare well with recorded TC shaft motions, both in amplitude and frequency content. The benchmarking lends credence to the validity of the integrated computational model.
Visibility Computations in Polyhedral Environments (1992)

The cell-to-cell visibility preprocessing and query algorithms for 2D axial floor-plans (presented at SIGGRAPH ''91) have been extended to cell-to-object visibility in 3D polyhedral environments, and an efficient implementation for 3D axial environments is demonstrated on a fully furnished architectural floor model with 250,000 polygons. The building is subdivided along the major walls into cells, connected through transparent portals. During preprocessing, cell-to-cell visibility is established for all cell pairs connected by at least one sight line through the intervening portals. Even for a source cell containing a generalized observer, often only a small portion of other cells is visible. Only objects whose bounding boxes intersect these volumesbecome part of the cell-to-object visibility set of the source cell. In the real-time walk-through simulation, cell-to-object visibility is further pruned with the view frustum from the observer''s current position, and only the remaining objects, which still form an uncompromised superset of the truly visible polygons, are sent to the renderer. In our architectural floor model, this process removed on average about 95% of all polygons, and accelerated rendering speed by about a factor of seventeen.
Examination of Rare Missense Variants in the CHRNA5‐A3‐B4 Gene Cluster to Level of Response to Alcohol in the San Diego Sibling Pair Study (2013)

These results indicate that rare genetic variation in the CHRNA5-A3-B4 gene cluster contributes modestly to the LR to alcohol in the San Diego Sibling Pair study and may protect against AUDs. However, replication studies are needed to confirm our findings.