gebhart/patrepeval huggingface dataset:
Planning most-likely paths from overhead imagery (2010)

This paper is about planning paths from overhead imagery, the novelty of which is taking explicit account of uncertainty in terrain classification and spatial variation in terrain cost. The image is first classified using a multi-class Gaussian Process Classifier which provides probabilities of class membership at each location in the image. The probability of class membership at a particular grid location is then combined with a terrain cost evaluated at that location using a spatial Gaussian process. The resulting cost function is, in turn, passed to a planner. This allows both the uncertainty in terrain classification and spatial variations in terrain costs to be incorporated into the planned path. Because the cost of traversing a grid cell is now a probability density rather than a single scalar value, we can produce not only the most-likely shortest path between points on the map, but also sample from the cost map to produce a distribution of paths between the points. Results are shown in the form of planned paths over aerial maps, these paths are shown to vary in response to local variations in terrain cost.
Hydrophobic stabilisation of peptides to study the mechanism of protein folding (2021)

This thesis was scanned from the print manuscript for digital preservation and is copyright the author. Researchers can access this thesis by asking their local university, institution or public library to make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
Efficient Subspace-Based Estimator for Localization of Multiple Incoherently Distributed Sources (2008)

<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> In this paper, a new subspace-based algorithm for parametric estimation of angular parameters of multiple incoherently distributed sources is proposed. This approach consists of using the subspace principle without any eigendecomposition of the covariance matrix, so that it does not require the knowledge of the effective dimension of the pseudosignal subspace, and therefore the main difficulty of the existing subspace estimators can be avoided. The proposed idea relies on the use of the property of the inverse of the covariance matrix to exploit approximately the orthogonality property between column vectors of the noise-free covariance matrix and the sample pseudonoise subspace. The resulting estimator can be considered as a generalization of the Pisarenko's extended version of Capon's estimator from the case of point sources to the case of incoherently distributed sources. Theoretical expressions are derived for the variance and the bias of the proposed estimator due to finite sample effect. Compared with other known methods with comparable complexity, the proposed algorithm exhibits a better estimation performance, especially for close source separation, for large angular spread and for low signal-to-noise ratio. </para>
Studies on the syntheses of heterocyclic compounds and natural products. 999. Double enamine annelation of 3,4-dihydro-1-methyl-.beta.-carboline and isoquinoline derivatives with 6-methyl-2-pyrone-3,5-dicarboxylates and its application for the synthesis of (.+-.)-camptothecin (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStudies on the syntheses of heterocyclic compounds and natural products. 999. Double enamine annelation of 3,4-dihydro-1-methyl-.beta.-carboline and isoquinoline derivatives with 6-methyl-2-pyrone-3,5-dicarboxylates and its application for the synthesis of (.+-.)-camptothecinMasataka Ihara, Kazuharu Noguchi, Tatsushi Ohsawa, Keiichiro Fukumoto, and Tetsuji KametaniCite this: J. Org. Chem. 1983, 48, 19, 3150–3156Publication Date (Print):September 1, 1983Publication History Published online1 May 2002Published inissue 1 September 1983https://pubs.acs.org/doi/10.1021/jo00167a003https://doi.org/10.1021/jo00167a003research-articleACS PublicationsRequest reuse permissionsArticle Views271Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Choosing the best quality of service algorithm using OPNET simulation (2022)

The concept of quality of service (QoS) is a new computer technology. Previously, there was a slow internet connection to access the sites and it was slow to send information. But now, it requires speeding up the traffic and increasing the efficiency for audio and video. In this study, we discuss the concepts of QoS provided over the network to achieve these goals. This study aims to compare six algorithms to control the QoS, then, the best algorithm will be selected to improve the traffic. These algorithms are named first in first out (FIFO), priority queuing (PQ), custom queuing (CQ), CQ with low latency queuing (LLQ), weighted fair queuing (WFQ), WFQ with low latency queuing (LLQ), so the behavior of these algorithms can be measured. The results obtained by comparing between them using OPNETsimulation show that the best algorithm is the priority queuing algorithm, followed by CQ, then CQ with LLQ, then WFQ, then WFQ with LLQ and finally FIFO. All these results are plotted in the form of graphs to show the paths of these algorithms for the single state with an operation time of 5 minutes for each algorithm.
ROASTING OF SYNCRUDE OIL SANDS FLY ASH (2004)

AbstractAbstractThe response of Syncrude fly ash to salt roasting varied significantly from sample to sample and thus, the optimum roasting conditions cannot specifically be defined for the Syncrude fly ash, but occur between 800 and 900 °C and with salt additions of 10 to 25%. Water leach extractions of vanadium ranged from 40 to 80% under these conditions, but leaching with Na2CO3 or Na2SO4 gave a much more consistent range of extractions from 73 to 89%.Characterization of the Syncrude fly ash also showed considerable variation among ash samples. Quartz, hematite, pseudobrookite, NiTiO3 and cristobalite were identified in the as-received October 98 ash with albite forming on heating with no additives and hauynite forming during salt roasting. Quartz and anhydrite were the only crystalline phases identified in the as-received December 98 ash. The anhydrite reacts with aluminosilicates in the ash to form anorthitic and/or albitic feldspars on heating with or without NaCl.La réponse des cendres volantes de Syncrude à la calcination au sel variait beaucoup d'un échantillon à l'autre et l'on ne peut donc pas définir de façon spécifique les conditions optimales de calcination, mais elles se trouvent entre 800 et 900 °C, avec additions de 10 à 25% de sel. L'extraction du vanadium par lixiviation à l'eau variait de 40 à 80% sous ces conditions, mais la lixiviation avec du Na2CO3 ou du Na2SO4 a donné une gamme d'extraction beaucoup plus consistante de 73 à 89%.La caractérisation des cendres volantes de Syncrude montrait également une variation importante parmi les échantillons de cendre. On a identifié du quartz, de l'hématite, de la pseudobrookite, du NiTiO3 et de la cristobalite dans la cendre originale d'octobre 98, de l'albite se formant lors du chauffage sans additif et de l'hauynite se formant lors de la calcination au sel. Le quartz et l'anhydrite étaient les seules phases cristallines identifiées dans la cendre originale de décembre 98. L'anhydrite réagit avec les aluminosilicates de la cendre pour former des feldspaths anorthitiques et/ou albitiques lors du chauffage avec ou sans NaCl.
In Vitro and in Vivo Effects of Three Different Mitragyna speciosa Korth Leaf Extracts on Phase II Drug Metabolizing Enzymes—Glutathione Transferases (GSTs) (2010)

In the present study, we investigate the effects of three different Mitragyna speciosa extracts, namely methanolic, aqueous and total alkaloid extracts, on glutathione transferase-specific activity in male Sprague Dawley rat liver cytosol in vitro and in vivo. In the in vitro study, the effect of Mitragyna speciosa extracts (0.01 to 750 microg/mL) against the specific activity of glutathione transferases was examined in rat liver cytosolic fraction from untreated rats. Our data show concentration dependent inhibition of cytosolic GSTs when Mitragyna speciosa extract was added into the reaction mixture. At the highest concentration used, the methanolic extract showed the highest GSTs specific activity inhibition (61%), followed by aqueous (50%) and total alkaloid extract (43%), respectively. In in vivo study, three different dosages; 50, 100 and 200 mg/kg for methanolic and aqueous extracts and 5, 10 and 20 mg/kg for total alkaloid extract were given orally for 14 days. An increase in GST specific activity was generally observed. However, only Mitragyna speciosa aqueous extract with a dosage of 100 mg/kg showed significant results: 129% compared to control.
Numerical modeling of subsurface communication (1985)

Techniques are described for numerical modeling of through-the-earth communication. The basic problem considered is evaluation of the field at a surface or airborne station due to an antenna buried in the earth. Equations are given for the field of a point source in a homogeneous or stratified earth. These expressions involve infinite integrals over wave number, sometimes known as Sommerfield integrals. Numerical techniques used for evaluating these integrals are outlined. The problem of determining the current on a real antenna in the earth, including the effect of insulation, is considered. Results are included for the fields of a point source in homogeneous and stratified earths and the field of a finite insulated dipole. The results are for electromagnetic propagation in the ELF-VLF range, but the codes also can address propagation problems at higher frequencies.
Increased Plasma Concentrations of Activin A Predict Intraventricular Hemorrhage in Preterm Newborns (2006)

Activin A concentrations at birth are increased in preterm newborns who later develop IVH and may be useful for early identification of infants with hypoxic-ischemic brain insults who are at high risk for IVH.
Application of supergeneralized matched filters to target classification (2005)

The matched filter (MF) is the optimum linear operator for distinguishing between a fixed signal and noise, given the noise statistics. A generalized matched filter (GMF) is a linear filter that can handle the more difficult problem of a multiple-example signal set, and it reduces to a MF when the signal set has only one member. A supergeneralized matched filter (SGMF) is a set of GMFs and a procedure to combine their results nonlinearly to handle the multisignal problem even better. Obviously the SGMF contains the GMF as a special case. An algorithm for training SGMFs is presented, and it is shown that the algorithm performs quite well even for extremely difficult classification problems.
Prevalence of Cross Reactive Epitopes to Bovine Factor Va Light Chain Fragments in Normal and Patients Plasma. (2006)

Abstract Several reports have described the presence of antibodies to bovine coagulation factors, such as factor V, prothrombin and factor X in plasma samples obtained from patients exposed to topical bovine thrombin. Other reports have also demonstrated the presence of anti-bovine coagulation factors in patients who have not been exposed to bovine thrombins, suggesting that anti-bovine protein antibodies can be generated in normal individuals. It has been suggested that surgical patients treated with topical bovine thrombin develop specific antibodies to bovine factor V which may be responsible for the bleeding and thrombotic complications. However, there is no definitive clinical study demonstrating a relationship between the apparent hemostatic defects and the presence of bovine factor Va antibodies. It was hypothesized that bovine factor Va antibodies are usually present in patients plasma because of the exposure to dietary bovine products. To test this hypothesis plasma samples from patients with end state renal disease (ESRD)(n=80), acute coronary syndrome (ACS)(n=160), burns (n=40) and healthy normal volunteers (n=140) were profiled for the presence of human factor V antigen (HFVA), bovine FVa antigen as measured by using a modified Elisa method and western blotting methods where bovine factor Va light chain fragment is used as a probe. In contrast to the normals (89±12%), the factor V antigen levels were found to be increased in the ESRD (148±30%), ACS (164±41%) and burn (145±27%) patients. Thus, there appears to be an up regulation of factor V antigen in these patients. All of the groups tested for the presence of immunoreactive material to the bovine factor Va light chain exhibited 2–3 ug/ml levels which were not significantly different. However, in the western blotting studies all groups exhibited cross reactivity with the factor Va light epitopes. There were bands present in the molecular weight range of 22, 36, 45 and 97 Kda in both the ESRD and burn patients. In the ACS patients there was an additional band observed at 166 Kda. These observations underscore the notion that bovine antifactor Va antibodies are non-specific and highly prevalent in both the surgical/interventional patients and normal population. A possible explanation for the presence of these antibodies is that most normal individual and patients problem are exposed to bovine proteins. Moreover, the higher prevalence of these antibodies in the ESRD and ACS patients may be due to additional exposure to heparin and aprotonin.
Incorporation d'agents thérapeutiques sur des matrices phosphocalciques (2005)

Communication par affiche intitulée (présentée par H. Roussière) : Incorporation d'agents thérapeutiques sur des matrices phosphocalciques
Vibronic spectra ofCu2+in ZnTe (1992)

Infrared-absorption spectra of substitutional ${\mathrm{Cu}}^{2+}$ ions in ZnTe have been measured at 4.6 K. Several distinct absorption peaks are observed between 800 and 2000 ${\mathrm{cm}}^{\mathrm{\ensuremath{-}}1}$. Absorption peaks at 1002 and 1069 ${\mathrm{cm}}^{\mathrm{\ensuremath{-}}1}$ are identified as zero-phonon lines arising from $^{2}$${\mathit{T}}_{2}$${\ensuremath{\rightarrow}}^{2}$E transitions. Between 1069 and 2000 ${\mathrm{cm}}^{\mathrm{\ensuremath{-}}1}$ several sets of sharp absorption lines are seen to recur regularly at an interval of 210 ${\mathrm{cm}}^{\mathrm{\ensuremath{-}}1}$, corresponding to the LO phonon energy. Within each set distinct vibronic sidebands that cannot be identified with critical-point energies of TA, LA, TO, or LO phonon modes are observed. A dynamic Jahn-Teller effect, involving coupling between a single-phonon mode and the electronic states of the $^{2}$E level, is proposed to account for the observed spectra. The spectra are adequately described by a Jahn-Teller interaction in the linear-coupling approximation and by including only coupling to \ensuremath{\epsilon} cluster modes. The observed first-order spin-orbit splitting in the $^{2}$${\mathit{T}}_{2}$ state is much reduced from crystal-field-theory predictions and a dynamic Jahn-Teller interaction in the ground $^{2}$${\mathit{T}}_{2}$ state is shown to account for this effect.
A piezoelectric micro-energy harvester for nanosensors (2015)

A novel piezoelectric micro-energy generator is presented, which converts the mechanical vibrations into electricity by utilizing the piezoelectric effect of zinc oxide nanowires (ZnO NW). This is the first time an integrated energy harvester is built where vertically standing NWs are directly coupled to a MEMS proof-mass for maximum conversion of the vibration energy while maintaining the size in the order of hundreds of micrometers. Hydrothermal growth of nanowires combined with MEMS surface micromachining technology and LIGA is employed to fabricate the device. Patterned SU-8 photoresist confines the growth area of the NW block, located between the silicon substrate and a suspended silicon nitride membrane, on which a nickel proof-mass is electroplated. A piezoelectric potential between the two ends of the NW block is formed once compressed by the membrane due to external vibration. A maximum power of 42 pW across 5.5 MΩ load is measured at the vibration frequency of 40 Hz with an acceleration of 1.4g. The corresponding output voltage is 14.7 mV.
Increased use of hypnotics in individuals with celiac disease: a nationwide case-control study (2015)

In conclusion, individuals with celiac disease suffer an increased risk of poor sleep, both before and after diagnosis. Although we cannot rule out that surveillance bias has contributed to our findings, our results are consistent with previous data suggesting that sleep complaints may be a manifestation of celiac disease.
Chronic Antidepressant Administration Increases the Expression of cAMP-Specific Phosphodiesterase 4A and 4B Isoforms (1999)

The influence of chronic antidepressant administration on expression of the three major phosphodiesterase (PDE) 4 subtypes found in brain (PDE4A, PDE4B, and PDE4D) was examined. The treatments tested included representatives of four major classes of antidepressants: selective reuptake inhibitors of serotonin (sertraline and fluoxetine) or norepinephrine (desipramine), a monoamine oxidase inhibitor (tranylcypromine), and electroconvulsive seizure. Expression of PDE4A and PDE4B, but not PDE4D, mRNA and immunoreactivity were significantly increased in rat frontal cortex by chronic administration of each of the four classes of antidepressants. We also found that antidepressant administration significantly increased the expression of PDE4B mRNA in the nucleus accumbens, a brain region thought to mediate pleasure and reward that could also contribute to the anhedonia often observed in depressed patients. In contrast, expression of PDE4A and PDE4B were not influenced by short-term treatment (1 or 7 d) and were not influenced by chronic administration of nonantidepressant psychotropic drugs (cocaine or haloperidol), demonstrating the time dependence and pharmacological specificity of these effects. Upregulation of PDE4A and PDE4B may represent a compensatory response to antidepressant treatment and activation of the cAMP system. The possibility that targeted inhibition of these PDE4 subtypes may produce an antidepressant effect is discussed.
Autonomic Dysfunction in Early Parkinson's Disease: Results from the United Kingdom Tracking Parkinson's Study (2016)

Autonomic dysfunction is common in early PD. Autonomic dysfunction correlates with the presence of other NMS, and with worse quality of life.
CSIRO - working towards gluten free beer (2012)

In 2011, CSIRO scientists visited the Coeliac Australia office in Sydney, to discuss the breeding of low gluten barley varieties, and the development of a new method to measure gluten (hordein) in beer.
Is there a weak H‐bond → LBHB transition on tetrahedral complex formation in serine proteases? (2003)

The transformation of a weak hydrogen bond in the free enzyme into a low-barrier hydrogen bond (LBHB) in the tetrahedral intermediate has been suggested as an important factor facilitating catalysis in serine proteases. In this work, we examine the structure of the H-bond in the Asp102-His57 diad of serine proteases in the free enzyme and in a covalent tetrahedral complex (TC) with a trifluoromethylketone inhibitor. We apply ab initio quantum mechanical calculations to models consisting of a large molecular fragment of the enzyme active site, and the combined effect of the rest of the protein body and the solvation by surrounding bulk water was simulated by a self-consistent reaction field method in our novel QM/SCRF(VS) approach. Potential profiles of adiabatic proton transfer in the Asp102-His57 diad in these model systems were calculated. We conclude that the hydrogen bond in both the free enzyme and in the enzyme-inhibitor TC is a strong ionic asymmetric one-well hydrogen bond, in contrast to a previous suggestion that it is a weak H-bond in the former and a double-well LBHB in the latter.
A trapped charge compensation scheme for ISFET based translinear circuits (2018)

A trapped charge compensation scheme for ISFET based translinear circuits is presented, as part of a system for prediction of cancer risk, based on DNA methylation. Each pixel is able to measure a DNA methylation ratio through pH-based measurements and by using in-pixel comparison to a tunable threshold, to output a result which indicates percentage of methylation used as a cancer score. The developed system was designed in a 0.35 μm CMOS technology and uses a novel trapped charge compensation scheme for ISFETs used in translinear circuits. The output scheme was able to compensate trapped charge of up to 380mV, with a ratio error below 5%, in a range of ratios between 50% and 80% which is generated from pH-based DNA methylation reactions.
Fibrinolysis after an Elective Caesarean Section without Postpartum Hemorrhage: Pilot Study for Reference Values from the Simultaneous Thrombin and Plasmin Generation Assays (2021)

ntroduction: Postpartum Hemorrhage (PPH)-induced coagulopathy should be better explored. An innovative Simultaneous Generation of Thrombin and Plasmin Assay (SGTPA) was developed. Objective: To establish postpartum SGTPA references. Methods: Blood samples collected immediately after delivery (T0) and then 30, 60, 120 and 360 minutes later. Thrombin Generation (TG) and Plasmin Generation (PG) changes over time analyzed in 51 women after elective cesarean section without PPH and compared with Non-Pregnant (NP) women. The SGTPA variables’ correlations with fibrinogen levels, D-dimer levels and physiological blood loss were assessed in a mixed model. Results: 37 women were included. TG and PG were higher in the postpartum group than in the NP group. TG increased early and then remained stable (baseline TG Area Under the Curve (AUC) [95% Confidence Interval (CI)] = 41037 [36850-43537] nM.min). The fibrinogen level varied over time, along with TG (p&lt;0.001). Plasmin generation increased from 30 to 120 minutes (AUC [95% CI]: 2104 [1437; 2613] nM.min), along with a change in the D-dimer level (p=0.018). The time to the plasmin peak and the time interval between the TG and PG peaks showed the greatest inter-individual variability at T0 and were associated with physiological volumes of blood loss during cesarean delivery. Conclusion: Reference SGTPA postpartum range was established. The SGTPA appears to be valuable for measuring TG and PG. TG and coagulation activation increased immediately after delivery, whereas PG and fibrinolysis increased later.