gebhart/patrepeval huggingface dataset:
Circulating immune complexes and immunoglobulin M-class rheumatoid factor in rats bearing mammary adenocarcinomas which vary in ability to metastasize. (1983)

In order to explore whether immune complex (IC) formation and immunoglobulin M-class rheumatoid factor (RF) synthesis are related to tumor progression, solid-phase enzyme immunoassays were used to test for ICs and RF in rats bearing three different syngeneic mammary adenocarcinomas. The mammary adenocarcinoma cell lines used produced either extensive metastasis (13762), metastasis in only a proportion of the animals given injections (R3230AC), or no metastasis (DMBA8). DMBA8 and 13762 tumor-bearing rats developed only low levels of circulating ICs. Of 18 animals bearing R3230AC tumors, four developed palpable lymph node metastasis (macrometastasis), while another five showed evidence of metastasis only upon histological examination (micrometastasis). R3230AC tumor-bearing animals which did not develop metastasis were found to have significantly higher IC levels than those rats with metastasis. Several sera from rats bearing R3230AC tumors were fractionated by molecular sieve chromatography. Most of the ICs in these sera were 7S to 19S in size. Significant RF synthesis occurred only in rats bearing R3230AC tumors and only during terminal tumor growth. These results show that IC formation and RF synthesis varies in animals bearing different mammary adenocarcinomas.
Understanding Mobile Phone Situated Sustainability: The Influence of Local Constraints and Practices on Transferability (2009)

Consumers discard roughly 125 million mobile phones into landfills every year. The authors explore how local and community factors affect mobile phone sustainability.
Intramolecular photoinduced processes of newly synthesized dual zinc porphyrin-fullerene triad with flexible linkers (2006)

Zinc porphyrin-fullerene-zinc porphyrin triad, in which two zinc porphyrin ( ZnP ) moieties and a fullerene ( C 60 ) moiety are linked by flexible bonds and which is intended to be a working model of the photosynthetic antenna-reaction centre, has been newly synthesized. Its photophysical properties have been investigated by both time-resolved emission and transient absorption techniques. Excitation of the zinc porphyrin moiety of the triad induced charge separation, generating the radical ion pair, in which the electron localizes on the C 60 moiety and the hole localizes on the zinc porphyrin moiety. In polar solvents, the charge-separated states decayed with lifetimes of 300-600 ns returning to the ground state. Compared with ZnP - C 60 dyad, ZnP - C 60 - ZnP triad showed longer lifetimes for the radical ion pair due to the conformation of the two ZnP moieties. The effects of the coordinating reagents on the zinc atom have been studied, with the expectation of conformational change of the two ZnP moieties with respect to C 60 .
Mdm2 Promotes Genetic Instability and Transformation Independent of p53 (2008)

Mdm2, a regulator of the tumor suppressor p53, is frequently overexpressed in human malignancies. Mdm2 also has unresolved, p53-independent functions that contribute to tumorigenesis. Here, we show that increased Mdm2 expression induced chromosome/chromatid breaks and delayed DNA double-strand break repair in cells lacking p53 but not in cells with a mutant form of Nbs1, a component of the Mre11/Rad50/Nbs1 DNA repair complex. A 31-amino-acid region of Mdm2 was necessary for binding to Nbs1. Mutation of conserved amino acids in the Nbs1 binding domain of Mdm2 inhibited Mdm2-Nbs1 association and prevented Mdm2 from delaying phosphorylation of H2AX and ATM-S/TQ sites, repair of DNA breaks, and resolution of DNA damage foci. Similarly, the mutation of eight amino acids in the Mdm2 binding domain of Nbs1 inhibited Mdm2-Nbs1 interaction and blocked the ability of Mdm2 to delay DNA break repair. Both Nbs1 and ATM, but not the ubiquitin ligase activity of Mdm2, were necessary to inhibit DNA break repair. Only Mdm2 with an intact Nbs1 binding domain was able to increase the frequency of chromosome/chromatid breaks and the transformation efficiency of cells lacking p53. Therefore, the interaction of Mdm2 with Nbs1 inhibited DNA break repair, leading to chromosome instability and subsequent transformation that was independent of p53.
Experimental Study on Electrochemical Machining with Electrolyte Confined by Absorption Material (2020)

Electrochemical machining (ECM) is a promising approach to manufacture micro textures on the metallic workpiece surface. However, due to the fluidity of the electrolyte, the undercutting and stray corrosion always exist on the processing surface which make the surface shape and integrity difficult to control. This paper proposed a new surface texturing processing method called ECM with electrolyte confined by absorption material (ECM-ECAM). During machining, the non-metallic absorption material is inserted between the cathodic tool and the anodic workpiece after absorbing the electrolyte. Since the flowing electrolyte is replaced with the electrolyte that is absorbed and confined in the absorption material, limitation of the electrolyte existing area and the machining area is realized. In this way, micro textures could be generated with an effective voltage applied between the cathode and the workpiece. The machining principle, designed and fabricated machining system and the machining results are presented in this paper.
In situ observation of homogeneous nucleation of nanosized zeolite A (2006)

The formation of zeolite A (LTA) in the presence of tetramethylammonium cations is studied using in situ small angle and wide angle X-ray scattering (SAXS/WAXS) techniques. The SAXS measurements show the formation of homogeneous precursors 10 nm in size prior to the crystallization of LTA which were consumed during the crystallization. The crystal size is estimated by fitting the SAXS patterns with an equation for a cubic particle, and it is revealed that the final crystal size of the LTA depends on the synthesis temperature. However, although such temperature dependence is noted for the final crystal size, the initial precursor particles size appears to be closely similar (ca. 10 nm) irrespective of the synthesis temperature.
Novel Oral Anticoagulant vs. Warfarin in Elderly Atrial Fibrillation Patients with Normal, Mid-Range, and Reduced Left Ventricular Ejection Fraction (2020)

In elderly AF patients ≥65 years, using NOAC was associated with lower IS/SE compared with warfarin in normal and mid-range LVEF but not in reduced LVEF. Using NOACs was associated with lower death compared with warfarin in normal LVEF.
Columnar epitaxy of hexagonal and orthorhombic silicides on Si(111) (1990)

Columnar grains of PtSi and CrSi2 surrounded by high-quality epitaxial silicon are obtained by ultrahigh vacuum codeposition of Si and metal in an approximately 10:1 ratio on Si(111) substrates heated to 610-840 C. This result is similar to that found previously for CoSi2 (a nearly-lattice-matched cubic-fluorite crystal) on Si(111), in spite of the respective orthorhombic and hexagonal structures of PtSi and CrSi2. The PtSi grains are epitaxial and have one of three variants of the relation defined by PtSi(010)/Si(111), with PtSi 001 line/Si 110 line type.
Privacy-Preserving Non-Participatory Surveillance System for COVID-19-Like Pandemics (2021)

COVID-19 pandemic has revealed a pressing need for an effective surveillance system to control the spread of infection. However, the existing systems are run by the people's smartphones and without a strong participation from the people, the systems become ineffective. Moreover, these systems can be misused to spy on people and breach their privacy. Due to recent privacy breaches, people became anxious about their privacy, and without privacy reassurance, the people may not accept the systems. In this paper, we propose a non-participatory privacy-preserving surveillance system for COVID-19-like pandemics. The system aims to control the spread of COVID-19 infection without depending on the participation of the people and with privacy preservation. In the proposed system, surveillance cameras of public places take images of visitors and compute embedding vectors that encode the facial features of the images by using deep learning techniques. A searchable encryption scheme is used by public places to encrypt the embedding vectors and send them to a cloud server (service manager). Similarly, hospitals and test centers send the encryptions of the embedding vectors of the images of positively-tested people to the cloud server. Finally, the server does operations on encrypted data to learn whether an infected person visited a public place for contact tracing without being able to learn the images or identify the visitors of the places and the infected persons, and then it alerts these places to take precautionary measures. Our analysis indicates that our system is secure and can preserve privacy. Our experimental results demonstrate that our system has high success rate and low false alarm rate, and needs low computation and communication overhead and acceptable search time.
Experimental and Statistical Studies: Applications of Newer Statistical Techniques (1942)

Paul Blommers, E. F. Lindquist, Experimental and Statistical Studies: Applications of Newer Statistical Techniques, Review of Educational Research, Vol. 12, No. 5, Methods of Research and Appraisal in Education (Dec., 1942), pp. 501-520
Curcumin loaded mesoporous silica: an effective drug delivery system for cancer treatment (2015)

In the present study, we report the delivery of anti-cancer drug curcumin to cancer cells using mesoporous silica materials. A series of mesoporous silica material based drug delivery systems (S2, S4 and S6) were first designed and developed through the amine functionalization of KIT-6, MSU-2 and MCM-41 followed by the loading of curcumin. The curcumin loaded materials were characterized with several physico-chemical techniques and thoroughly screened on cancer cells to evaluate their in vitro drug delivery efficacy. All the curcumin loaded silica materials exhibited higher cellular uptake and inhibition of cancer cell viability compared to pristine curcumin. The effective internalization of curcumin in cancer cells through the mesoporous silica materials initiated the generation of intracellular reactive oxygen species and the down regulation of poly ADP ribose polymerase (PARP) enzyme levels compared to free curcumin leading to the activation of apoptosis. This study shows that the anti-cancer activity of curcumin can be potentiated by loading onto mesoporous silica materials. Therefore, we strongly believe that mesoporous silica based curcumin loaded drug delivery systems may have future potential applications for the treatment of cancers.
Double-Seeding of Er/Yb Co-Doped Fiber Amplifiers for Controlling of Yb-ASE (2013)

In this paper, we present our investigations on controlling the amplified spontaneous emission from Yb ions in erbium/ytterbium co-doped fiber amplifier by double-seeding of the amplifier with nominal (1.55 μm) and auxiliary (1 μm). The dependence of the amplifier output power on the auxiliary seed wavelength and input power is analyzed. The obtained results are discussed and compared to a conventional amplifier setup without auxiliary seed signal. Our studies show that introducing an auxiliary seed at proper wavelength from the Yb-band provides stable amplifier operation without parasitic lasing at 1 μm and can also increase output power of the nominal 1550 nm signal.
Machining-Induced Residual Stress: Experimentation and Modeling (1999)

Controlled orthogonal and controlled oblique machining of annealed AISI 4340 have been undertaken in a design of experiments framework to investigate the machining-induced residual stresses resulting from these processes. The experimentation demonstrates significant simplifications in the machining-induced residual stress problem when the stresses are expressed in a coordinate system fixed in the tool and also indicates that the directions along the cutting edge and normal to the cutting edge of the tool are principal directions of the machining-induced residual stresses. Based on the experimental results, a plane strain thermoelastoplastic model of metal flow under the flank of a cutting tool is developed to predict the full in-plane biaxial residual stress profiles existing at and beneath the newly created surface. Calibrated results show favorable agreement with the experimental machining-induced residual stresses in annealed AISI 4340. [S1087-1357(00)00201-X]
Lacidipine, hydrochlorothiazide and their combination in systolic hypertension in the elderly (1997)

In treating elderly systolic hypertensives the diuretic hydrochlorothiazide is a more effective antihypertensive agent with a longer duration of action than is the calcium channel antagonist lacidipine. In combination the effects of these two drugs on blood pressure are additive.
Effect of biaxial stretching of nanolayered poly(ethylene furanoate) (PEF) films on gas barrier properties (2021)

Alain Guinault, from PIMM/CNAM, participated online in the international conference of the polymer processing society to represent the last results obtained in the framework of the MyPack project.
H.264/AVC baseline profile decoder complexity analysis (2003)

We study and analyze the computational complexity of a software-based H.264/AVC (advanced video codec) baseline profile decoder. Our analysis is based on determining the number of basic computational operations required by a decoder to perform the key decoding subfunctions. The frequency of use of each of the required decoding subfunctions is empirically derived using bitstreams generated from two different encoders for a variety of content, resolutions and bit rates. Using the measured frequencies, estimates of the decoder time complexity for various hardware platforms can be determined. A detailed example is provided to assist in deriving time complexity estimates. We compare the resulting estimates to numbers measured for an optimized decoder on the Pentium 3 hardware platform. We then use those numbers to evaluate the dependence of the time complexity of each of the major decoder subfunctions on encoder characteristics, content, resolution and bit rate. Finally, we compare an H.264/AVC-compliant baseline decoder to a decoder that is compliant with the H.263 standard, which is currently dominant in interactive video applications. Both "C" only decoder implementations were compared on a Pentium 3 hardware platform. Our results indicate that an H.264/AVC baseline decoder is approximately 2.5 times more time complex than an H.263 baseline decoder.
Implementation of a wide-angle lens distortion correction algorithm on the cell broadband engine (2009)

Wide-angle lenses are often used in scientific or virtual reality applications to enlarge the field of view of a conventional camera. Wide-angle lens distortion correction is an image warping application which transforms the distorted images back to the natural-looking, central perspective space. This application is characterized by a non-linear streaming memory access pattern that makes main memory bandwidth a key performance limiter.
Lead Halide Perovskites as Quantum Dot Sensitizers for Mesoscopic TiO2 Photovoltaic Cells (2009)

Abstract not Available.
Cultural Condition for the mycelial growth of Ganoderma lucidum on Cereals (1996)

Cereals were used as solid-substrate for the cultivation of Ganoderma lucidum. The hydration time with cold water appeared to be 10, 11 and 12 hours for Malt, Danyeob and Black soybeans respectively, and the water content was enough for mycelial growth in this condition. The hydration times required for sorghum, job's tears, barley, brown rice and wheat were 2.5, 4, 5, 10 and 12 hours respectively, but the final water content was much less than optimum water content (65%). Hot water reduced the hydration time of soybeans, and the water content reached to 65% within mins. This condition showed the optimum for the mycelial growth. For the other cereals, it took about mins to reach the optimum water content (65%). From this result, hot water was better than cold water for the hydration of cereals. We attempted to develop a practically applicable process by combining the soaking and sterilization. This process was successful with soybean and about 1.1 times of water based on the weight of soybean appeared to be suitable. In all varieties of cereal, the water content of 65% appeared to be the best for the growth of the fungi and production of glucosamine related to the amount of mycelium. The mycelial growth rate in accordance with kinds of solid-state materials was in the order of barley > wheat > job's tears > sorghum > brown rice > soybean. The glucosamine content for determing the mycelial growth in solid material was in the order of wheat> barley > brown rice > job's tears > sorghum > soybean.
Effect of organic and inorganic fertilisers on natural food composition and performance of African catfish fry produced under artificial propagation (2017)

In recent times, the African catfish, Clarias gariepinus has gained popularity in the aquaculture sector of Tanzania. However, many aquaculture farmers face the challenge of unreliable supply of seed due to difficulties of reproducing in captivity and high larvae mortality. This study was conducted to determine the effect of organic and inorganic fertilizers on natural food composition and performance of African catfish fry produced under artificial propagation. A completely randomized and factorial experimental design were adopted with three replication for a one week and two months period of time, respectively. Plankton abundance and diversity, growth performance and survival rate of African catfish fry were determined. One way and two way analysis of variance (ANOVA) were used to determine differences between treatments (p&lt;0.05). Post-hoc analysis was done where significant differences existed between treatments using Tukey’s Test. Results indicated that phytoplankton abundance and diversity were significantly higher (p&lt;0.05) in di-ammonium phosphate (DAP) fertilizer applied tanks compared to chicken manure and no fertilizer. Zooplankton diversity was also higher in tanks applied with chicken manure in comparison with other treatments. Growth performance was higher in fertilized tanks compared to unfertilized tanks at low stocking density (5fry/m2). There was no significant difference (p&gt;0.05) in fry survival rates between chicken manure and DAP fertilized treatments across stocking densities. Water quality parameters were within the optimum ranges.
A CMOS Imager With Focal Plane Compression Using Predictive Coding (2007)

This paper presents a CMOS image sensor with focal-plane compression. The design has a column-level architecture and it is based on predictive coding techniques for image decorrelation. The prediction operations are performed in the analog domain to avoid quantization noise and to decrease the area complexity of the circuit. The prediction residuals are quantized and encoded by a joint quantizer/coder circuit. To save area resources, the joint quantizer/coder circuit exploits common circuitry between a single-slope analog-to-digital converter (ADC) and a Golomb-Rice entropy coder. This combination of ADC and encoder allows the integration of the entropy coder at the column level. A prototype chip was fabricated in a 0.35 mum CMOS process. The output of the chip is a compressed bit stream. The test chip occupies a silicon area of 2.60 mm times 5.96 mm which includes an 80 times 44 APS array. Tests of the fabricated chip demonstrate the validity of the design.
The impact of the MYB-NFIB fusion proto-oncogene in vivo (2016)

Recurrent fusion of the v-myb avian myelobastosis viral oncogene homolog (MYB) and nuclear factor I/B (NFIB) generates the MYB-NFIB transcription factor, which has been detected in a high percentage of individuals with adenoid cystic carcinoma (ACC). To understand the functional role of this fusion protein in carcinogenesis, we generated a conditional mutant transgenic mouse that expresses MYB-NFIB along with p53 mutation in tissues that give rise to ACC: mammary tissue, salivary glands, or systemically in the whole body. Expression of the oncogene in mammary tissue resulted in hyperplastic glands that developed into adenocarcinoma in 27.3% of animals. Systemic expression of the MYB-NFIB fusion caused more rapid development of this breast phenotype, but mice died due to abnormal proliferation in the glomerular compartment of the kidney, which led to development of glomerulonephritis. These findings suggest the MYB-NFIB fusion is oncogenic and treatments targeting this transcription factor may lead to therapeutic responses in ACC patients.
Pressure driven adsorption cycle integrated with thermal desalination (2022)

The canned food market is growing at an annually average rate of 3.6% due to easy access and awareness of dietary requirements, leading to a surge in water withdrawal and an estimated supply-demand gap of 40% by 2030. The conventional desalination processes are not sustainable due to high energy requirements and chemicals injection. The adsorption cycle is an emerging technology for desalination due to its temperature operation. It has many advantages over conventional desalination processes including integration synergy to improve overall performance. The conventional AD cycle processes, however, have lower performance due to inefficient packing of adsorbent in the beds and heat transfer losses to their massive heat exchangers. In this article, we propose an innovative pressure driven adsorption (PDAD) cycle to overcome conventional AD cycle limitations. In PDAD, firstly, low pressure steam is used to regenerate the adsorbent which eliminates the huge infrastructure requirement of water circulation and secondly, steam selectively extracts water vapours from pores, reducing energy consumption. We have tested the PDAD pilot and showed successful regeneration of silica gel at motive steam pressure of 2–5 bar. We also demonstrate that discharge steam from the PDAD at 65 °C can be used as a heat source for a multi effect desalination system when operating in hybrid mode to overcome its operational limitations. Our experiments show that the MED + PDAD cycle increases water production by up to 22% as compared to an earlier hybrid MEDAD cycle. The proposed system has excellent thermodynamic synergy with the combined CCGT power and desalination plant, where low-pressure bleed steam can be utilized more efficiently.
Acoustic Model Adaptation In Reverberant Conditions Using Multi-task Learned Embeddings (2022)

Acoustic environment plays a major role in the performance of a large-scale Automatic Speech Recognition (ASR) system. It becomes a lot more challenging when substantial amount of distortions, such as background noise and reverberations are present. Of late, it has been standard to use i-vectors for Acoustic Model (AM) adaptation. Embeddings from Single Task Learned (STL) neural network systems, such as x-vectors and r-vectors, have also been used to a varying degree of success. This paper proposes the use of Multi Task Learned (MTL) embeddings for large vocabulary hybrid acoustic model adaptation in reverberant environments. MTL embeddings are extracted from an affine layer of the deep neural network trained on multiple tasks such as speaker information and room information. Our experiments show that the proposed MTL embeddings outperform i-vectors, x-vectors and r-vectors for AM adaptation in reverberant conditions. Besides, it has been demonstrated that the proposed MTL-embeddings can be fused with i-vectors to provide further improvement. We provide results on artificially reverberated Librispeech data as well as real world reverberated HRRE data. On Librispeech database, the proposed method provides an improvement of 10.9% and 8.7% relative to i-vector in reverberated test-clean and test-other data respectively, while an improvement of 7% is observed relative to i-vector when the proposed system is tested on HRRE dataset.