gebhart/patrepeval huggingface dataset:
Building the Web of Things: With examples in Node.js and Raspberry Pi (2016)

Summary A hands-on guide that will teach how to design and implement scalable, flexible, and open IoT solutions using web technologies. This book focuses on providing the right balance of theory, code samples, and practical examples to enable you to successfully connect all sorts of devices to the web and to expose their services and data over REST APIs. Purchase of the print book includes a free eBook in PDF, Kindle, and ePub formats from Manning Publications. About the Technology Because the Internet of Things is still new, there is no universal application protocol. Fortunately, the IoT can take advantage of the web, where IoT protocols connect applications thanks to universal and open APIs. About the Book Building the Web of Things is a guide to using cutting-edge web technologies to build the IoT. This step-by-step book teaches you how to use web protocols to connect real-world devices to the web, including the Semantic and Social Webs. Along the way you'll gain vital concepts as you follow instructions for making Web of Things devices. By the end, you'll have the practical skills you need to implement your own web-connected products and services. What's Inside Introduction to IoT protocols and devices Connect electronic actuators and sensors (GPIO) to a Raspberry Pi Implement standard REST and Pub/Sub APIs with Node.js on embedded systems Learn about IoT protocols like MQTT and CoAP and integrate them to the Web of Things Use the Semantic Web (JSON-LD, RDFa, etc.) to discover and find Web Things Share Things via Social Networks to create the Social Web of Things Build a web-based smart home with HTTP and Web Socket Compose physical mashups with EVRYTHNG, Node-RED, and IFTTT About the Reader For both seasoned programmers and those with only basic programming skills. About the Authors Dominique Guinard and Vlad Trifa pioneered the Web of Things and cofounded EVRYTHNG, a large-scale IoT cloud powering billions of Web Things.
Energy enhancement of short-period dispersion-managed solitons (2000)

Summary form only given. In nonlinear optical communication systems, the improvement in performance achieved by dispersion-managed (DM) solitons compared to conventional solitons is widely known. The use of short pulses in conventional dispersion-managed systems, for a realistic map strength (S), causes the local dispersions (/spl beta//sub 1,11/) to approach the average dispersion for practical amplifier spacings. This limitation can be overcome by the use of short-period dispersion maps (SPDMs). The short-period dispersion management regime is characterized by the period of the dispersion management (Z/sub p/) being much shorter than the amplifier spacing (Z/sub a/), which is in contrast to conventional dispersion-management regime (Z/sub p//spl ges/Z/sub a/). A schematic representation of a SPDM is shown. We investigate the energy dependence of DM solitons in SPDMs by numerical simulation. We examine the effects of reducing the ratio Z/sub p/:Z/sub a/, whilst maintaining a fixed S and minimum pulse width. We then contrast the performance of SPDMs and conventional dispersion maps in a transmission simulation at 40 Gbit/s.
A Modeling Study of Soot and De-NOx Reaction Phenomena in SCRF Systems (2011)

&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;The development of thermally durable zeolite NH&lt;sub&gt;3&lt;/sub&gt;/Urea-SCR formulations coupled with that of high porosity filters substrates has opened the way to integrate PM and NOx control into a single device, namely an SCR-coated Diesel Particulate Filter (SCRF). A few experimental works are already present in the literature regarding SCRF systems, mainly addressing the DeNOx performances of the system (in both presence and absence of soot) under both steady state and transient conditions. The purpose of the present work is to perform a simulation study focused on phenomena which are expected to play key roles in SCRF systems, such as coupling of reaction and diffusion phenomena, soot effect on DeNOx activity, SCR coating effect on soot regeneration and filtration efficiency and competition between soot oxidation and DeNOx processes involving NO&lt;sub&gt;2&lt;/sub&gt;. Subsequently, a concept analysis was carried out to comparatively study a DOC+SCRF system and a DOC+DPF+SCR one with respect to the continuously regeneration (CRT®) operation.&lt;/div&gt;&lt;/div&gt;
F-1410 A Modelling of presumption to the Mental Work Load for man-machine systems (2001)

When we evaluate the man-machine systems, it is very important to consider not only the performance of the machine system but also the Mental Work Load (MWL) for the operator. Therefore, we construct a model using the Heart Rate Variability to analyze the relationship between the driver's MWL and the factor of the MWL. In this analysis, we construct two kinds of model. One is Multiple regression modeling for the linear analysis, and the other is Neural network modeling for the non-linear analysis. Finally, we propose the possibility that an analytical method of the model can be used to assessment of the man-machine systems.
Local control of the host immune response performed with mesenchymal stem cells: perspectives for functional intracerebral xenotransplantation (2014)

Foetal pig neuroblasts are interesting candidates as a cell source for transplantation, but xenotransplantation in the brain requires the development of adapted immunosuppressive treatments. As systemic administration of high doses of cyclosporine A has side effects and does not protect xenotransplants forever, we focused our work on local control of the host immune responses. We studied the advantage of cotransplanting syngenic mesenchymal stem cells (MSC) with porcine neuroblasts (pNb) in immunocompetent rat striata. Two groups of animals were transplanted, either with pNb alone or with both MSC and pNb. At day 63, no porcine neurons were detected in the striata that received only pNb, while four of six rats transplanted with both pNb and MSC exhibited healthy porcine neurons. Interestingly, 50% of the cotransplanted rats displayed healthy grafts with pNF70+ and TH+ neurons at 120 days post-transplantation. qPCR analyses revealed a general dwindling of pro- and anti-inflammatory cytokines in the striata that received the cotransplants. Motor recovery was also observed following the transplantation of pNb and MSC in a rat model of Parkinson's disease. Taken together, the present data indicate that the immunosuppressive properties of MSC are of great interest for the long-term survival of xenogeneic neurons in the brain.
Nanoporous Tungsten for Improved Mechanical Performance and Safety in Nuclear Control Rod Cladding (2018)

Driven by both the implications of the recent disaster in Fukushima as well as the coming maturity of fusion reactors in energy infrastructure, the nuclear industry is experiencing a renaissance not only in reactor design and fuel systems but also in safety.However, the combination of high temperature, high pressure, and radiation intensity of a reactor core poses a challenge to material selection for engineers, particularly related to nuclear cladding.For example, in a pressurized water reactor, the most prevalent reactor type currently in operation, control rod cladding can be subjected to temperatures over 500 • C, pressures at 15 MPa, and a neutron flux of 3.5 × 10 19 neutrons per cm 2 s.Thus, creep and cracking pose a threat to the cladding's functional integrity.As a result, high fracture toughness, low thermal expansion coefficient, and wear resistance become crucial metrics for the design and selection of nuclear cladding material for control rods.In response to these metrics, boron carbide (B4C) and Ag-In-Cd alloy have emerged as promising candidates for usage in control rod claddings.However, nanoporosity can impart significant mechanical advantages including higher fracture toughness, increased defect annihilation, and suppressed irradiation swelling.Density-modulated tungsten thin films with tunable nanoporosity can be manufactured through sputter coating.Consequently, density-modulated tungsten thin films have the potential to contribute to next-generation control rod cladding.Thus, the objective of this paper is to investigate the suitability of density-modulated tungsten thin films for nuclear control rod cladding through the analytical hierarchy process.Overall, conservative analytical hierarchy process analysis indicates that nanoporous tungsten is competitive with B4C for control rod cladding.As a result, our study may motivate current and future control rod cladding material development efforts focusing specifically on hybrid density-modulated tungsten thin film and B4C architectures for next-generation nuclear power plants.
XXVIIIth EAVA Congress Paris, France 28-31/07/2010 FOREWORD (2010)

International audience
Graded coatings for metallic implant alloys - eScholarship (2002)

Graded glass and glass-hydroxyapatite coatings on Ti-based and Co-Cr alloys have been prepared using a simple enameling technique. The composition of the glasses has been tailored to match the thermal expansion of the alloys. By controlling the firing time, and temperature, it has been possible to control the reactivity between the glass and the alloy and to fabricate coatings (25 to 150 mu m thick) with excellent adhesion to the substrate, resistant to corrosion and able to precipitate hydroxyapatite during in vitro tests in simulated body fluid.
The ovulatory gonadotrophin surge stimulates cyclooxygenase expression and prostaglandin production by the monkey follicle (2001)

Follicular prostaglandin concentrations increase following the gonadotrophin surge in domestic animals and rodents approximately 10 h before follicle rupture, suggesting a unifying role for prostaglandins in the timing of ovulation. However, little is known about prostaglandin production by the primate ovulatory follicle. In this study, adult female macaques received gonadotrophins to promote follicular development. Granulosa cells, follicular fluid, and ovaries were collected before (0 h) and 12, 24 or 36 h after administration of the ovulatory stimulus, human chorionic gonadotrophin (HCG). Cyclooxygenase (COX) isoform expression was assessed by reverse transcription-polymerase chain reaction and immunocytochemistry and follicular prostaglandin production was determined by enzyme immunoassay. COX-2 mRNA expression in granulosa cells was low at 0 h, rose 50-fold by 12 h, and remained elevated through to 36 h. COX-2 immunostaining was present in granulosa cells after, but not before, exposure to HCG. COX-1 mRNA levels did not change during the periovulatory interval, and COX-1 immunostaining of granulosa cells was not detected. Follicular fluid prostaglandin (PG) E (2) and PGF (2alpha) concentrations were low through to 24 h but increased 100-fold at 36 h. The elevated follicular prostaglandin concentrations 4-16 h before the expected time of ovulation support the hypothesis that the time between the LH surge and increased follicular prostaglandins determines the length of the periovulatory period. Differences between the localization and timing of COX-2 expression in monkey versus non-primate follicles suggest that the pattern of COX-2 expression and activity has aspects unique to primates.
Data and Expert Models for Sleep Timing and Chronotype Estimation from Smartphone Context Data and Simulations (2018)

We present a sleep timing estimation approach that combines data-driven estimators with an expert model and uses smartphone context data. Our data-driven methodology comprises a classifier trained on features from smartphone sensors. Another classifier uses time as input. Expert knowledge is incorporated via the human circadian and homeostatic two process model. We investigate the two process model as output filter on classifier results and as fusion method to combine sensor and time classifiers. We analyse sleep timing estimation performance, in data from a two-week free-living study of 13 participants and sensor data simulations of arbitrary sleep schedules, amounting to 98280 nights. Five intuitive sleep parameters were derived to control the simulation. Moreover, we investigate model personalisation, by retraining classifiers based on participant feedback. The joint data and expert model yields an average relative estimation error of -2±62 min for sleep onset and -5±70 min for wake (absolute errors 40±48 min and 42±57 min, mean median absolute deviation 22 min and 15 min), which significantly outperforms data-driven methods. Moreover, the data and expert models combination remains robust under varying sleep schedules. Personalising data models with user feedback from the last two days showed the largest performance gain of 57% for sleep onset and 59% for wake up. Our power-efficient smartphone app makes convenient everyday sleep monitoring finally realistic.
Concordia (2021)

Virtualized Radio Access Network (vRAN) offers a cost-efficient solution for running the 5G RAN as a virtualized network function (VNF) on commodity hardware. The vRAN is more efficient than traditional RANs, as it multiplexes several base station workloads on the same compute hardware. Our measurements show that, whilst this multiplexing provides efficiency gains, more than 50% of the CPU cycles in typical vRAN settings still remain unused. A way to further improve CPU utilization is to collocate the vRAN with general-purpose workloads. However, to maintain performance, vRAN tasks have sub-millisecond latency requirements that have to be met 99.999% of times. We show that this is difficult to achieve with existing systems. We propose Concordia, a userspace deadline scheduling framework for the vRAN on Linux. Concordia builds prediction models using quantile decision trees to predict the worst case execution times of vRAN signal processing tasks. The Concordia scheduler is fast (runs every 20 us) and the prediction models are accurate, enabling the system to reserve a minimum number of cores required for vRAN tasks, leaving the rest for general-purpose workloads. We evaluate Concordia on a commercial-grade reference vRAN platform. We show that it meets the 99.999% reliability requirements and reclaims more than 70% of idle CPU cycles without affecting the RAN performance.
Electron beam crosslinking of poly(vinylmethyl ether) (1994)

Abstract The electron beam induced branching of poly(vinylmethyl ether) (PVME) in bulk and in isopropanol solutions has been studied by gel permeation chromatography. The branching probability of bulk PVME induced by high‐energy electrons can be characterized by gel permeation chromatography and a simple probability constant obtained. In isopropanol solutions this branching probability is not constant as a function of dose and is found to decrease with decreasing concentration. These results indicate the importance of solvent effects on the crosslinking of PVME in isopropanol solution by electron beam radiation. © 1994 John Wiley &amp; Sons, Inc.
Protocol-Driven Management of Suspected Common Duct Stones (2017)

Protocol-driven management of patients with suspected common duct stones reduced the number of endoscopies and length of hospitalization, with no change in postoperative morbidity. This approach has the potential to decrease endoscopy-related morbidity and overall cost without affecting quality of care.
Characterization of Fibrinogen Binding by Glycoproteins Srr1 and Srr2 of Streptococcus agalactiae (2013)

The serine-rich repeat glycoproteins of Gram-positive bacteria comprise a large family of cell wall proteins. Streptococcus agalactiae (group B streptococcus, GBS) expresses either Srr1 or Srr2 on its surface, depending on the strain. Srr1 has recently been shown to bind fibrinogen, and this interaction contributes to the pathogenesis of GBS meningitis. Although strains expressing Srr2 appear to be hypervirulent, no ligand for this adhesin has been described. We now demonstrate that Srr2 also binds human fibrinogen and that this interaction promotes GBS attachment to endothelial cells. Recombinant Srr1 and Srr2 bound fibrinogen in vitro, with affinities of KD = 2.1 × 10(-5) and 3.7 × 10(-6) M, respectively, as measured by surface plasmon resonance spectroscopy. The binding site for Srr1 and Srr2 was localized to tandem repeats 6-8 of the fibrinogen Aα chain. The structures of both the Srr1 and Srr2 binding regions were determined and, in combination with mutagenesis studies, suggest that both Srr1 and Srr2 interact with a segment of these repeats via a "dock, lock, and latch" mechanism. Moreover, properties of the latch region may account for the increased affinity between Srr2 and fibrinogen. Together, these studies identify how greater affinity of Srr2 for fibrinogen may contribute to the increased virulence associated with Srr2-expressing strains.
High latitude temperature trends, tropical temperature trends and the Brewer-Dobson circulation, 1979-2008 (2010)

We examine monthly trends in brightness temperature data from the lower stratospheric channel of microwave sounding unit (MSU T4/TLS). As a consequence of the Brewer-Dobson circulation (BDC), there is a large degree of coupling between the interannual variability of temperatures at high latitudes and in the tropics. We use this relationship to show that the 1979-2008 warming trend at northern high latitudes in January, and southern high latitudes in September is congruent with a net strengthening of the BDC at these times, in agreement with previous work that used reanalysis data (Lin et al., 2009; Fu et al., 2009). We also examine the potential drivers of a BDC slowdown during northern hemisphere spring, evident by a high latitude cooling trend during March. Furthermore, we suggest that the tropical-high latitude relationship can be used to improve uncertainties in stratospheric trends.
The emerging roles of long noncoding RNAs in lymphatic vascular development and disease (2023)

Recent advances in RNA sequencing technologies helped uncover what was once uncharted territory in the human genome-the complex and versatile world of long noncoding RNAs (lncRNAs). Previously thought of as merely transcriptional "noise", lncRNAs have now emerged as essential regulators of gene expression networks controlling development, homeostasis and disease progression. The regulatory functions of lncRNAs are broad and diverse, and the underlying molecular mechanisms are highly variable, acting at the transcriptional, post-transcriptional, translational, and post-translational levels. In recent years, evidence has accumulated to support the important role of lncRNAs in the development and functioning of the lymphatic vasculature and associated pathological processes such as tumor-induced lymphangiogenesis and cancer metastasis. In this review, we summarize the current knowledge on the role of lncRNAs in regulating the key genes and pathways involved in lymphatic vascular development and disease. Furthermore, we discuss the potential of lncRNAs as novel therapeutic targets and outline possible strategies for the development of lncRNA-based therapeutics to treat diseases of the lymphatic system.
Development of low temperature specimen stage and its applications to electron holographic measurement (1986)

Using electron holography, information about a specimen, such as distributions of magnetization and thickness, can be revealed by investigating the shape of reconstructed wavefronts of the laser beam. These distinctive features can be utilized in investigations in the fields of superconductivity and biology. Therefore, we have developed a low temperature specimen stage which is reguired for superconducting specimens and to decrease the radiation damage in biological specimens. Using this cold stage, we have observed magnetic flux quantization in superconductors.
Lethal perinatal osteogenesis imperfecta due to a type I collagen α2(I) gly to arg substitution detected by chemical cleavage of an mRNA:cDNA sequence mismatch (1992)

A single base mismatch was detected by a chemical cleavage method in heteroduplexes formed between patient mRNA and a control collagen alpha 2(I) cDNA probe in a case of osteogenesis imperfecta type II. The region of the mRNA mismatch was amplified using the polymerase chain reaction, cloned and sequenced. A heterozygous point mutation of G to C at base pair 1,774 of the collagen alpha 2(I) mRNA resulted in the substitution of glycine with arginine at amino acid position 457 of the helix. Type I collagen of alpha 1(I)- and alpha 2(I)-chains from the patient migrated slowly on electrophoresis due to increased levels of posttranslational modification of lysine. The parents' fibroblast collagen did not contain the mRNA mismatch and the collagens showed normal electrophoretic behaviour. Two-dimensional electrophoresis of the CNBr peptides from the patient's collagen confirmed the excessive posttranslational modification of the alpha 1(I)- and alpha 2(I)-chains in the CNBr peptides N-terminal to the mutation due to disruption of the obligatory Gly-X-Y triplet repeat of the helix. The mutation led to reduced procollagen secretion and helix destabilization as evidenced by a decreased thermal stability. These data lend further support to the accumulating evidence that type I collagen alpha 2(I) glycine substitution mutations result in the same spectrum of clinical severity as those in the alpha 1(I)-chain.(ABSTRACT TRUNCATED AT 250 WORDS)
Involvement of CHOP in activin A‑induced myeloma NS‑1 cell apoptosis (2019)

Activin A, a multifunctional cytokine, is a member of transforming growth factor‑β (TGF‑β) superfamily. It is associated with a variety of pathophysiological processes, including inflammation, fibrosis, and tumorigenesis. Chronic or prolonged endoplasmic reticulum (ER) stress can lead to cells apoptosis. However, whether ER stress‑related proteins, such as CHOP, GADD34 are involved in activin A‑induced myeloma cell apoptosis remains unknown. In the present study, it was revealed that activin A inhibited the proliferation of myeloma cell line NS‑1 cells and induced NS‑1 cell apoptosis. Activin A upregulated the expression of CHOP, GADD34, caspase‑3, and caspase‑12. Moreover, both Smad3 and p‑Smad3 levels were increased with treatment of activin A. Further studies revealed that the overexpression of activin signaling protein Smad3 in NS‑1 cells increased the levels of CHOP, caspase‑3, and p‑Smad3. These data indicated that the CHOP protein of the ER stress pathway may be involved in activin A‑induced NS‑1 cell apoptosis, and also indicated the potential therapy of activin A‑induced apoptosis via CHOP signaling for multiple myeloma.
Inkjet printing and UV-LED curing of photochromic dyes for functional and smart textile applications (2018)

Health concerns as a result of harmful UV-rays drive the development of UV-sensors of different kinds. In this research, a UV-responsive smart textile is produced by inkjet printing and UV-LED curing of a specifically designed photochromic ink on PET fabric. This paper focuses on tuning and characterizing the colour performance of a photochromic dye embedded in a UV-curable ink resin. The influence of industrial fabrication parameters on the crosslinking density of the UV-resin and hence on the colour kinetics is investigated. A lower crosslinking density of the UV-resin increases the kinetic switching speed of the photochromic dye molecules upon isomerization. By introducing an extended kinetic model, which defines rate constants <i>k</i> <sub>colouration</sub>, <i>k</i> <sub>decay</sub> and <i>k</i> <sub>decolouration</sub>, the colour performance of photochromic textiles can be predicted. Fabrication parameters present a flexible and fast alternative to polymer conjugation to control kinetics of photochromic dyes in a resin. In particular, industrial fabrication parameters during printing and curing of the photochromic ink are used to set the colour yield, colouration/decolouration rates and the durability, which are important characteristics towards the development of a UV-sensor for smart textile applications.