gebhart/patrepeval huggingface dataset:
DEM–PBM modeling of abrasion dominated ribbon breakage (2017)

In dry granulation, fine cohesive powders are compacted into large multi‐particle entities, i.e., briquettes, flakes, or ribbons. The powder compaction is generally followed by milling, a size reduction process, which is crucial to obtain the desired granule size or properties. Abrasion and impact are two primary mechanisms of comminution in ribbon milling, but they are not completely understood. The aim of this article was hence to investigate numerically the fragmentation process induced by abrasion during ribbon milling. The discrete element method (DEM) was employed to simulate abrasion tests, for which three‐dimensional parallelepiped ribbons were generated using auto‐adhesive elastic spheres. The fragmentation rate, and the fragments size and number were determined for various surface energies and abrasive velocities. The DEM results showed that the mass‐equivalent fragment size distributions were bi‐modal, similar to the experimental observations and the numerical results for impact‐dominated ribbon milling reported in the literature. In addition, two quantities were determined from the DEM analysis, i.e., the number of large fragments and the fraction of fines, which was then integrated into the population balance models (PBM) so that a DEM–PBM multiscale modeling framework was developed to predict the granule size distribution during ribbon milling. The DEM–PBM results were compared with the experimental results reported in the literature, and a broad agreement was obtained, implying the proposed DEM–PBM can be used to analyse the ribbon milling behavior. © 2017 American Institute of Chemical Engineers AIChE J , 64: 1191–1204, 2018
TSS-1R Failure Mode Evaluation (1997)

Soon after the break of the tether during the Tethered Satellite System (TSS-1R) mission in February, 1996, a Tiger Team was assembled at the George C. Marshall Space Flight Center to determine the tether failure mode. One possible failure scenario was the Kevlar' strength member of the tether failed because of degradation due to electrical discharge or electrical arcing. During the next several weeks, extensive electrical discharge testing in low vacuum and plasma environments was conducted in an attempt to reproduce the electrical activity recorded by on-board science instruments during the mission. The results of these tests are presented in this paper.
Motion and equilibrium of a spheromak in a toroidal flux conserver (1991)

A number of experiments have been performed on spheromaks injected into the empty vacuum vessel of the Caltech ENCORE tokamak (i.e., without tokamak plasma) [Phys. Rev. Lett. 64, 2144 (1990); Phys. Fluids B 2, 1306 (1990)]. Magnetic probe arrays (in a number of configurations) have been used to make single shot, unaveraged, in situ measurements of the spheromak equilibrium. These measurements are important because (i) they reveal for the first time the equilibrium structure of spheromaks in a toroidal geometry, (ii) they provide a reliable estimate of magnetic helicity and energy of spheromak plasmas used in injection experiments [Phys. Rev. Lett. 64, 2144 (1990)], and (iii) they constitute the first measurements of spheromak motion across and interaction with static magnetic fields (which are useful in corroborating recent theories). Probe measurements in the tokamak dc toroidal field show for the first time that the spheromak exhibits a ‘‘double tilt.’’ The spheromak first tilts while in the cylindrical entrance region, emerging into the tokamak vessel antialigned to the dc toroidal field, then expands into the tokamak vacuum vessel, and finally tilts again to form an oblate (nonaxisymmetric, m=1) configuration. In addition, the spheromak drifts vertically in the direction given by Jcenter×Btok, where Jcenter is the unbalanced poloidal current that threads the center of the spheromak torus. Probe arrays at different toroidal locations show that the spheromak shifts toroidally (horizontally left or right) in the direction opposite that of the static toroidal field. In the absence of toroidal flux, the m=1 object develops a helical pitch, the sense of the pitch depending on the sign of the spheromak helicity. The spheromak equilibrium in the toroidal vessel is well fit by a pressureless infinite cylindrical model; however, there is evidence of deviation from m=1 symmetry because of toroidal effects, nonuniform J/B profile, and finite β. Experiments performed in a test facility consisting of the spheromak gun and a replica of the entrance region (with a closed end) show that the spheromak is generated with its axis coaxial with that of the gun. Coherent, m=2 magnetic modes are observed during the formation stage rotating in the E×B direction at about 125 kHz (rotation velocity corresponding to 40% of the Alfvén speed).
Adsorption of sulfur on bimetallic surfaces: Formation of copper sulfides on Pt(111) and Ru(001) (1995)

The interaction of sulfur and copper on Pt(111) and Ru(001) has been examined using x-ray photoelectron spectroscopy and thermal desorption mass spectroscopy. Cu/Pt(111) and Cu/Ru(001) surfaces were exposed to S2 gas at 300 K. It was found that for both substrates stable copper–sulfide films were formed, of which the Cu–S/Ru(001) system was the more stable. The decomposition of the Cu2S films on Pt(111) occurred at 600–850 K and on Ru(001) at 900–1000 K. Breakdown of the films led to evolution into the gas phase of sulfur (mainly as S2) without desorption of copper or the sulfur chemisorbed on the substrate. This chemisorbed sulfur desorbed in a broad feature from 1000 to 1500 K. For the Ru(001) substrate the Cu atoms remained on the surface until they desorbed at 1080 K, while on Pt(111) the Cu atoms migrated into the Pt(111) surface to form a subsurface Cu–Pt alloy; no Cu desorption features were seen at temperatures as high as 1300 K. On Pt(111), copper sulfide promoted the formation of a bulklike platinum sulfide. No sulfidation of ruthenium was detected in the presence of copper–sulfide films. For both substrates the sulfur atoms were found to highly perturb the copper sites, decreasing the ability of the noble-metal adatoms to adsorb CO.
A Convenient Synthesis of Diacyl Sulfides Using a Novel Sulfur Transfer Reagent. (2004)

Abstract For Abstract see ChemInform Abstract in Full Text.
Determining the three-dimensional atomic structure of a metallic glass (2020)

Abstract Amorphous solids such as glass are ubiquitous in our daily life and have found broad applications ranging from window glass and solar cells to telecommunications and transformer cores 1,2 . However, due to the lack of long-range order, the three-dimensional (3D) atomic structure of amorphous solids have thus far defied any direct experimental determination without model fitting 3-13 . Here, using a multi-component metallic glass as a proof-of-principle, we advance atomic electron tomography to determine the 3D atomic positions in an amorphous solid for the first time. We quantitatively characterize the short-range order (SRO) and medium-range order (MRO) of the 3D atomic arrangement. We find that although the 3D atomic packing of the SRO is geometrically disordered, some SRO connect with each other to form crystal-like networks and give rise to MRO. We identify four crystal-like MRO networks - face-centred cubic, hexagonal close-packed, body-centered cubic and simple cubic - coexisting in the sample, which show translational but no orientational order. These observations confirm that the 3D atomic structure in some parts of the sample is consistent with the efficient cluster packing mode l8,10-12,20 . Looking forward, we anticipate this experiment will open the door to determining the 3D atomic coordinates of various amorphous solids, whose impact on non-crystalline solids may be comparable to the first 3D crystal structure solved by x-ray crystallography over a century ago 14 .
α−Lipoic Acid: Biological Effects and Clinical Implications (1997)

α− Lipoic acid is unique in its ability to act as an antioxidant in fat- and watersoluble tissues in both its oxidized and reduced forms. It is readily absorbed from an oral dose. Because of its myriad biological activities, including an ability to chelate metals and to scavenge a wide array of free radicals, α− lipoic acid is considered by several experts to be an ideal antioxidant. Clinical applications for this nutrient include the following conditions: diabetic polyneuropathy, cataracts, glaucoma, ischemia− reperfusion injury, and Amanita mushroom poisoning. Because of its unique characteristics α− lipoic acid is likely to have therapeutic application in a wide range of additional clinical conditions. (Alt Med Rev 1997; 2(3):177-183)
Synthesis and n.m.r.-spectral analysis of unenriched and [1-13C]-enriched 5-deoxypentoses and 5-O-methylpentoses (1987)

Chemical methods are described for preparing unenriched and [1-13C]-enriched 5-deoxy- and 5-O-methyl-pentoses in the D or L configuration. The 1H-n.m.r. spectra of these compounds have been interpreted, and the 13C-n.m.r. spectra assigned with the aid of 2-D 13C-1H chemical-shift correlation spectroscopy. Tautomeric forms (furanoses, hydrate, and aldehyde) in solution in 2H2O have been quantified with the aid of [1-13C]-enriched derivatives. Spectra of 5-deoxypentoses, 5-O-methylpentoses, and methyl pentofuranosides have been compared, in order to assess the effect of 5-C-deoxygenation and 5-O-methylation on chemical shifts and coupling constants (1H-1H, 13C-1H, and 13C-13C) and on the pentofuranose conformations.
Local Descriptor for Robust Place Recognition Using LiDAR Intensity (2019)

Place recognition is a challenging problem in mobile robotics, especially in unstructured environments or under viewpoint and illumination changes. Most LiDAR-based methods rely on geometrical features to overcome such challenges, as generally scene geometry is invariant to these changes, but tend to affect camera-based solutions significantly. Compared to cameras, however, LiDARs lack the strong and descriptive appearance information that imaging can provide. To combine the benefits of geometry and appearance, we propose coupling the conventional geometric information from the LiDAR with its calibrated intensity return. This strategy extracts extremely useful information in the form of a new descriptor design, coined ISHOT, outperforming popular state-of-the-art geometric-only descriptors by significant margin in our local descriptor evaluation. To complete the framework, we furthermore develop a probabilistic keypoint voting place recognition algorithm, leveraging the new descriptor and yielding sublinear place recognition performance. The efficacy of our approach is validated in challenging global localization experiments in large-scale built-up and unstructured environments.
Thrombo-embolic complication after streptokinase therapy of pulmonary emboli. (1988)

A 58-year old patient is reported who developed an ischaemic cerebrovascular accident 22 hours after successful thrombolysis with streptokinase for life-threatening pulmonary emboli. Despite effective thrombolysis, the plasma fibrinogen level rose during streptokinase administration and reached extremely high values 72 hours later. The mechanism of this unusual early and extreme rise of fibrinogen levels is unclear but it probably played a role in the pathogenesis of the cerebrovascular accident.
Ac Insertion Site Affects the Frequency of Transposon-Induced Homologous Recombination at the Maize p1 Locus (2000)

The maize p1 gene regulates the production of a red pigment in the kernel pericarp, cob, and other maize floral tissues. Insertions of the transposable element Ac can induce recombination between two highly homologous 5.2-kb direct repeat sequences that flank the p1 gene-coding region. Here, we tested the effects of the Ac insertion site and orientation on the induction of recombination at the p1 locus. A collection of unique p1 gene alleles was used, which carry Ac insertions at different sites in and near the p1 locus, outside of the direct repeats, within the direct repeat sequences, and between the direct repeats, in both orientations. Recombination was scored by the numbers of colorless pericarp sectors (somatic frequency) and heritable mutations (germinal frequency). In both the somatic and germinal tests, the frequency of homologous recombination is significantly higher when Ac is inserted between the direct repeats than when Ac is inserted either within or outside the repeats. In contrast, Ac orientation had no significant effect on recombination frequency. We discuss these results in terms of the possible mechanisms of transposon-induced recombination.
Détection et identification chimique par spectroscopie QCL sur des prélèvements d'air réalisés par microdrones : Interaction du champ électromagnétique avec l'environnement (2005)

La combinaison du laser a cascade quantique (QCLI et du developpement de la spectroscopie « intrapulse » permet d'atteindre un niveau sans precedent de detection et identification d'especes chimiques en phase gazeuse. L'association drone-systeme de detection pourrait etre la solution a de nombreuses problematiques concernant le controle de l'environnement pour des besoins civils ou militaires.
Synthesis and Antimicrobial Activity of Some Novel Schiff Bases Containing 1,2,4‐Triazole‐3‐thione (2010)

A series of Schiff bases (4a-j) were prepared by reacting 4‐amino‐5‐(1‐phenylethyl)‐2,4‐dihydro‐3 H ‐1,2,4‐triazole‐3‐thione and substituted aromatic aldehydes. The chemical structures were confirmed by means of UV, 1 H NMR, IR, MS(API‐ES) spectral data and elemental analysis. All the synthesized compounds were screened for their antimicrobial activity. Among the tested compounds, Schiff bases with 4‐OH and 4‐NO 2 substituent exhibited remarkable antimicrobial activity against all the tested microorganism.
P‐73: A Method of Generating Full Color LCD Using Birefringent Filters in a Stacked Design (2000)

Abstract We discuss the design and performance of a full color transmissive display based on the folded Solc filter design. Sharp et. al. suggested the use of a modified Solc filter as a colorswitch and for use as a display device. Del Pico suggested its use as a direct view device using plastic substrates and LCP's to solve some parallax issues. However no details of its operation were given. The design incorporates three individual stacks each responsible for producing RGB without the use of color filters, this offer high color purity and brightness along with the promise of low power consumption. In this paper the design of such a system is considered in detail.
Directionally Solidified DS CM 247 LC—Optimized Mechanical Properties Resulting From Extensive γ′ Solutioning (1985)

Complete coarse γ′ and greater than 90% eutectic γ-γ′ solutioning, without incipient melting, is demonstrated for the DS CM 247 LC superalloy. This unusual capability for this advanced Ni-base turbine blade and vane material results in considerable mechanical properties enhancement, with the DS alloy capability being near to current single crystal superalloys in the 345–207 MPa, 871°C–982°C (50–30 ksi, 1600°F–1800°F) operating condition. Microstructural features are detailed correlating strength and alloy stability.
Flicker evoked increase in optic nerve head blood flow in anesthetized cats (1991)

The effect of diffuse luminance flicker stimulation of a large area (approximately 30 degrees diameter) on red blood cell flux (F) in the optic nerve head was measured in the anesthetized cat. F increased markedly during sustained flicker. The F-response to the initiation and cessation of the stimulation was found to occur within a few seconds. Upon sustained stimulation, the increase in F reached a plateau within approximately 2 min. Its level depended upon the intensity, frequency and wavelength of the stimulation and the state of adaptation of the retina. This stimulus offers a new and powerful means of investigating blood flow regulation in the optic nerve head (ONH).
Equivalent outcomes with minimally invasive and sternotomy mitral valve repair for degenerative mitral valve disease (2021)

Minimally invasive and sternotomy mitral valve repair in patients with degenerative mitral valve disease is associated with equivalent survival and repair durability.
Oral immunization of mice and swine with an attenuated Salmonella choleraesuis [delta cya-12 delta(crp-cdt)19] mutant containing a recombinant plasmid (1993)

Salmonella choleraesuis chi 3781, an attenuated [delta cya-12 delta(crp-cdt)19] mutant, was electroporated with the plasmid pBA31-R7, which codes for the expression of a 31-kDa protein from Brucella abortus (BCSP31). Recombinant S. choleraesuis chi 3781 stably maintained the pBA31-R7 plasmid and continued to express the cloned protein following recovery of the organism from orally inoculated animals. Unlike previous studies using S. typhimurium chi 4064(pBA31-R7), S. choleraesuis chi 3781(pBA31-R7) was able to colonize both the gut mucosa and deep tissues of both BALB/cByJ mice and crossbred swine. Orally inoculated mice developed serum antibodies to both the cloned 31-kDa protein (rBCSP31) and to S. choleraesuis chi 3781 endotoxin. These mice also developed a local intestinal antibody response to Salmonella endotoxin but not to rBCSP31. Similarly, mice inoculated with recombinant S. choleraesuis chi 3781 did not develop a delayed-type hypersensitivity (DTH) footpad response following injection with rBCSP31; however, these mice did respond to S. choleraesuis chi 3781 soluble antigen. Conversely, orally inoculated swine did not develop significant serum or intestinal antibody responses to cloned protein or Salmonella endotoxin, but DTH responses to both cloned protein and S. choleraesuis chi 3781 soluble antigen were strongly positive. The cell-mediated nature of these DTH responses was confirmed by histological examination. Results suggest that S. choleraesuis chi 3781 may be a suitable choice for further studies of vaccine efficacy in swine, especially for diseases which require cell-mediated immunity for resolution.
Energy cost of running (1963)

Indirect calorimetric measurements were made on two athletes running at different speeds up to 22 km/hr at grades from -20 to +15%; the function was found to be linearly related to speed. Within these limits, the net kilocalories per kilogram per kilometer values seem to be independent of speed and related only to the incline. These values are about 5–7% lower than those found in nonathletic subjects, which shows that training in atheletes does not lead to great improvement. A nomogram is given for easily calculating the energy expenditure in running when the speed and the incline are known. The energy cost per kilometer in horizontal run (1 kcal/kg) is about double that for walking at the most economical speed (4 km/ hr). Submitted on July 31, 1962
[Pharmacokinetics of subconjunctivally injected drugs in the anterior segment of rabbit eyes]. (1995)

We injected 12.5, 25, 50 and 100 microliters portions of a combined solution of 2.5% sodium fluorescein (FL), 2.5% cefmenoxim hemihydrochloride (CMX), and 0. 25% chloramphenicol (CP) subconjunctivally into rabbit eyes by various methods. Drug levels were monitored in the tears and aqueous humor and measured via high performance liquid chromatography. In the tear fluid, the concentrations of CP decreased more rapidly with time than FL and CMX. The drugs penetrated the rabbit's eyes better when injected subconjunctivally than when administered by sub-Tenon's injection. After subconjunctival injection through the eyelid, the drug concentration in the tears decreased with time in almost the same way as for injection through the conjunctival membrane. There was little difference between the presence and absence of a puncture hole in the conjunctiva. When the whole cornea was sealed with cyanoacrylate glue to block transcorneal absorption, the FL concentration in the aqueous humor was 30% of that in the control and the CP concentration was less than 10% of that in the control. About 70% of FL penetrating the eyes was derived from the transcorneal route but most of the CP was derived from the transcorneal route. FL in 1% or 0. 25% sodium hyarulonate (HA) and saline was injected subconjunctivally, and the concentrations of FL in the cornea and vitreous humor were measured. FL in 0.25% HA penetrated rabbit eyes better than that in 1% HA. These findings suggest that by dissolving the drug in an adequate concentration of HA solution, better penetration of drugs into the eye can be obtained.
DERMA: A Melanoma Diagnosis Platform Based on Collaborative Multilabel Analog Reasoning (2014)

The number of melanoma cancer-related death has increased over the last few years due to the new solar habits. Early diagnosis has become the best prevention method. This work presents a melanoma diagnosis architecture based on the collaboration of several multilabel case-based reasoning subsystems called DERMA. The system has to face up several challenges that include data characterization, pattern matching, reliable diagnosis, and self-explanation capabilities. Experiments using subsystems specialized in confocal and dermoscopy images have provided promising results for helping experts to assess melanoma diagnosis.
Clinical significance of expression of cancer/testis antigen and down-regulation of HLA class-I in patients with stage I non-small cell lung cancer. (2013)

Reduced expression of HLA class-I was an unfavorable prognostic factor in patients with positive expression of CT antigen, and represents an important hurdle to antigen-based cancer immunotherapy.
Heterogeneity of Human Serum High Density Lipoproteins on High Performance Liquid Chromatography1 (1982)

A combination method consisting of separation by HPLC using gel permeation columns and selective detection of cholesterol or choline-containing phospholipids was applied to the identification and quantitation of subclasses of high density lipoproteins in human serum. The frequency distribution of peaks in the elution patterns on detection of choline-containing phospholipids in a group (n = 71) of normal males and females showed five maxima. Their particle sizes were determined from the relation between Stokes' diameter and elution volume to be as follows: 122.0 +/- 2.8 A, 110.1 +/- 2.1 A, 97.5 +/- 1.8 A, 86.7 +/- 1.3 A, and 76.3 +/- 16 A. The two larger fractions were found to correspond to HDL2 subclasses, i.e., HDL2b and HDL2a. The other three peaks were found to reflect the subclasses of HDL3 and choline-containing phospholipids in the very high density lipoprotein fraction which sedimented at the bottom on ultracentrifugation at the density of 1.21. Moreover, the existence of these five subclasses in the HDL fraction was confirmed by rechromatography using this combination HPLC method. Our results for the particle sizes of HDL subclasses were confirmed by electron microscopy.
One-Step Preservation of Phosphoproteins and Tissue Morphology at Room Temperature for Diagnostic and Research Specimens (2011)

In a single paraffin block BHP preserved the phosphorylation state of several signaling proteins at a level comparable to snap-freezing, while maintaining the full diagnostic immunohistochemical and histomorphologic detail of formalin fixation. This new tissue fixative has the potential to greatly facilitate personalized medicine, biobanking, and phospho-proteomic research.