gebhart/patrepeval huggingface dataset:
Development of high harmonic generation spectroscopy of organic molecules and biomolecules (2016)

In this review we will discuss the topic of high order harmonic generation (HHG) from samples of organic and bio-molecules. The possibility to extract useful dynamical and structural information from the measurement of the HHG emission, a technique termed high harmonic generation spectroscopy (HHGS), will be the special focus of our discussions. We will begin by introducing the salient facts of HHG from atoms and simple molecules and explaining the principles behind HHGS. Next the technical difficulties associated with HHG from samples of organic molecules and biomolecules, principally the low sample density and the low ionization potential, will be examined. Then we will present some recent experiments where HHG spectra from samples of these molecules have been measured and discuss what has been learned from these measurements. Finally we will look at the future prospects for HHG spectroscopy of organic molecules, discussing some of the technical and in principle limits of the technique and methods that may ameliorate these limits.
PD65-11 MOLECULAR RATIONALE FOR TARGETING DNA-PKC TO ENHANCE UTILITY OF RADIATION THERAPY IN PROSTATE CANCER (2018)

B1/AMP-activated protein kinase (LKB1/AMPK) signaling pathway was analyzed using immunoblotting, immunoprecipitation, siRNA silencing and plasmid overexpression.
MIMO Time-Domain Equalization for High-Speed Continuous Transmission Under Channel Variability (2018)

High-speed communication over mutually coupled channels can be severely affected by intersymbol interference (ISI) and crosstalk (XT). Multiple-input multiple-output (MIMO) equalization is known to mitigate both ISI and XT, but requires accurate channel information at the receiver (RX) and/or transmitter (TX), when the channel is stochastic. However, since adjusting the equalization filters to the specific channel realization involves a considerable implementational and computational complexity, it is desirable to keep the equalization filters fixed irrespective of the specific channel realization, especially when the channel variability is relatively small. Therefore, we propose a general MIMO transceiver scheme where the equalization filters depend on the channel statistics rather than the actual channel. More specifically, by considering the time-domain equalization with the fixed linear MIMO pre-equalization and adjustable MIMO decision feedback equalization, the complexity associated with passing channel information from the RX to the TX is avoided, and the computationally intensive and iterative calculations of the fixed pre-equalizer can be performed offline rather than on-chip. The proposed equalization scheme is shown to yield only a small performance degradation compared to fully adjustable equalization schemes, thereby enabling multi-Gbit/s chip-to-chip communication over low-cost electrical interconnects which are prone to manufacturing tolerances.
Large and Small Scale Materials Testing of HT-9 Irradiated in the STIP Irradiation Program (2010)

The Fuel Cycle R&D (FCRD) initiative is investigating methods of burning minor actinides in a transmutation fuel. To achieve this goal, the fast reactor core materials must withstand very high doses. Small scale materials testing methods in addition to large scale materials testing allows one to gain more insight by providing more data on the same sample while being able to probe areas of interest which are not accessible otherwise. Furthermore, the sample volumes were so small that the tests could be considered a non destructive test since the amount of material needed is so small that a macroscopic structure would not be affected. Tensile testing, micro hardness testing and micro compression testing on focused ion beam (FIB) microscope manufactured pillars were performed on remaining parts of tensile test specimens tested and irradiated in the Spallation Target Irradiation Program (STIP). It is shown that the increases of yield strength measured by tensile testing, micro compression testing and micro hardness testing all showed the same trend. In addition FIB based techniques also allowed fabrication of LEAP samples of such a small size that their residual activity was below detectable levels thus allowing them to be handled and analyzed in a manner comparable to inactive specimens.
Session details: Evaluation and prediction of FPGA routing resources (2006)

No abstract available.
Partial silhouette-based gait recognition (2017)

Gait analysis refers to identification of a person from the systemic study of the motions of his/her different body parts at the time of walking. It is one of the behavioural biometric approaches to human identification. Like other behavioural approaches, gait also suffers from low-repeatability leading to poor recognition accuracy. Therefore, multimodal systems are required for better recognition accuracy. With the advent of multimodal biometric systems there is a need for low-cost methods for individual biometric modalities so that the overall complexity of the system does not overshoot the real-time requirements. In view of this, a partial-silhouette-based approach for gait recognition is reported in this article. This approach is translation, rotation and scale invariant and is low-cost in terms of computational complexity. Experimental results and comparative performance analysis on benchmark dataset reveal the potential of the partial-silhouette-based approach.
Additivity in the Analysis and Design of HIV Protease Inhibitors (2009)

We explore the applicability of an additive treatment of substituent effects to the analysis and design of HIV protease inhibitors. Affinity data for a set of inhibitors with a common chemical framework were analyzed to provide estimates of the free energy contribution of each chemical substituent. These estimates were then used to design new inhibitors whose high affinities were confirmed by synthesis and experimental testing. Derivations of additive models by least-squares and ridge-regression methods were found to yield statistically similar results. The additivity approach was also compared with standard molecular descriptor-based QSAR; the latter was not found to provide superior predictions. Crystallographic studies of HIV protease-inhibitor complexes help explain the perhaps surprisingly high degree of substituent additivity in this system, and allow some of the additivity coefficients to be rationalized on a structural basis.
A comprehensive effectiveness study of passive design parameters for traditional dwellings in Qinba mountainous area (2022)

Traditional dwelling has achieved harmony between building and climatic environment, which is one of the most significant prerequisites for sustainability. In this study, Liyuanba traditional dwellings were selected as the representative traditional dwellings in southwestern part of Qinba mountainous area, and passive design strategies extracted from traditional dwellings were utilized to improve its indoor thermal comfort. This research presents an approach in which the energy simulation, orthogonal arrays and range analysis were integrated to analyze the sensitivity of each passive parameter to overall energy-saving performance and to determine how energy consumption can be minimized by the optimal combination of them. The optimized passive strategy could reduce the annual energy consumption of the simulated dwelling by 65.1% compared with that of the original one and increase the indoor air temperature and mean radiation temperature by 4.31°C and 4.35°C in winter, respectively, meeting the requirements of the design standard for energy efficiency for rural residential buildings (GB/T50824-2013). Through the systematic study of passive parameters in the southwestern part of Qinba mountainous area, the optimal combination of passive design strategies could be utilized for the renovation of traditional dwellings to improve the building energy performance under the premise of satisfying the indoor thermal comfort.
Discovery of Hydrolysis-Resistant Isoindoline N-Acyl Amino Acid Analogues that Stimulate Mitochondrial Respiration (2018)

N-Acyl amino acids directly bind mitochondria and function as endogenous uncouplers of UCP1-independent respiration. We found that administration of N-acyl amino acids to mice improves glucose homeostasis and increases energy expenditure, indicating that this pathway might be useful for treating obesity and associated disorders. We report the full account of the synthesis and mitochondrial uncoupling bioactivity of lipidated N-acyl amino acids and their unnatural analogues. Unsaturated fatty acid chains of medium length and neutral amino acid head groups are required for optimal uncoupling activity on mammalian cells. A class of unnatural N-acyl amino acid analogues, characterized by isoindoline-1-carboxylate head groups (37), were resistant to enzymatic degradation by PM20D1 and maintained uncoupling bioactivity in cells and in mice.
Non dairy probiotic beverages. (2013)

The beneficial effects of food with added live microbes (probiotics) on human health are being increasingly promoted by health professionals. Probiotic products available in the markets today, are usually in the form of fermented milks and yoghurts; however, with an increase in the consumer vegetarianism throughout the developed countries, there is also a demand for the vegetarian probiotic products. And, owing to health considerations, from the perspective of cholesterol in dairy products for the developed countries, and economic reasons for the developing countries, alternative raw materials for probiotics need to be searched. Considering the above mentioned facts cereals, legumes, fruits and vegetables may be potential substrates, where the healthy probiotic bacteria will make their mark, both in the developing and the developed countries. This review aims at highlighting the research done on probiotic beverages from non dairy sources. These non dairy probiotic beverages can serve as a healthy alternative for dairy probiotics and also favor consumption by lactose intolerant consumers.
Correction of Carrier Frequency Offsets in OFDM-Based Spatial Multiplexing MIMO With Distributed Transmit Antennas (2008)

This correspondence focuses on the correction of carrier frequency offsets (CFOs) in orthogonal frequency-division multiplexing (OFDM)-based spatial multiplexing multi-input-multi-output (MIMO) with distributed transmit antennas, where the CFOs between the receiver and each transmit antenna are possibly different. Considering macroscopic fading and multipath Rayleigh fading, the average power of the intercarrier interference (ICI) caused by the CFOs is derived, and the optimal CFO correction value is then obtained by maximizing the average signal-to-interference-and-noise ratio (SINR). In particular, when the difference between the minimum and maximum values of the CFOs is no more than half of the adjacent subcarrier spacing, an upper bound of the average ICI power can be obtained, and a closed-form solution of the optimal CFO correction value is derived.
Toll-Like Receptor 4 Mediates Maladaptive Left Ventricular Remodeling and Impairs Cardiac Function After Myocardial Infarction (2007)

Left ventricular (LV) remodeling leads to congestive heart failure and is a main determinant of morbidity and mortality following myocardial infarction. Therapeutic options to prevent LV remodeling are limited, which necessitates the exploration of alternative therapeutic targets. Toll-like receptors (TLRs) serve as pattern recognition receptors within the innate immune system. Activation of TLR4 results in an inflammatory response and is involved in extracellular matrix degradation, both key processes of LV remodeling following myocardial infarction. To establish the role of TLR4 in postinfarct LV remodeling, myocardial infarction was induced in wild-type BALB/c mice and TLR4-defective C3H-Tlr4(LPS-d) mice. Without affecting infarct size, TLR4 defectiveness reduced the extent of LV remodeling (end-diastolic volume: 103.7+/-6.8 microL versus 128.5+/-5.7 microL; P<0.01) and preserved systolic function (ejection fraction: 28.2+/-3.1% versus 16.6+/-1.3%; P<0.01), as assessed by MRI. In the noninfarcted area, interstitial fibrosis, and myocardial hypertrophy were reduced in C3H-Tlr4(LPS-d) mice. In the infarcted area, however, collagen density was increased, which was accompanied by fewer macrophages, reduced inflammation regulating cytokine expression levels (interleukin [IL]-1alpha, IL-2, IL-4, IL-5, IL-6, IL-10, IL-17, tumor necrosis factor-alpha, interferon-gamma, granulocyte/macrophage colony-stimulating factor), and reduced matrix metalloproteinase-2 (4684+/-515 versus 7573+/-611; P=0.002) and matrix metalloproteinase-9 activity (76.0+/-14.3 versus 168.0+/-36.2; P=0.027). These data provide direct evidence for a causal role of TLR4 in postinfarct maladaptive LV remodeling, probably via inflammatory cytokine production and matrix degradation. TLR4 may therefore constitute a novel target in the treatment of ischemic heart failure.
Invariant fixed point in stratified continuum percolation (1989)

Stratified continuum percolation is a percolation model based upon self-similarity that can describe correlated transport and connectivity problems. It is demonstrated that this construction of correlated percolation retains some of the properties of random percolation. Most importantly, the critical threshold remains well defined, independent of changing correlations. These results introduce a new approach to understanding correlated flow systems.
Abraham Lincoln in the National Capital (1926)

Journal Article Abraham Lincoln in the National Capital. By Allen C. Clark. (Washington, 1925. x, 179 p.) Get access P. M. Hamer P. M. Hamer Search for other works by this author on: Oxford Academic Google Scholar Journal of American History, Volume 12, Issue 4, March 1926, Pages 605–606, https://doi.org/10.2307/1891260 Published: 01 March 1926
ChemInform Abstract: N‐HYDROXYALKYL‐MALEOPIMARSAEUREIMIDE (1971)

Abstract Die Reaktion der Maleopimarsäure (I) mit den Aminoalkoholen (IIa) in Methanol bei 50°C bzw. (IIb) in DMF bei 55‐120°C führt zu den Imiden (IIIa) (78% Ausbeute) bzw. (IIIb).
Quasirelativistic effects in the electronic structure of the thiomolybdate and thiotungstate complexes of nickel, palladium, and platinum (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTQuasirelativistic effects in the electronic structure of the thiomolybdate and thiotungstate complexes of nickel, palladium, and platinumB. D. El-Issa and M. M. ZeedanCite this: Inorg. Chem. 1991, 30, 12, 2594–2605Publication Date (Print):June 1, 1991Publication History Published online1 May 2002Published inissue 1 June 1991https://pubs.acs.org/doi/10.1021/ic00012a007https://doi.org/10.1021/ic00012a007research-articleACS PublicationsRequest reuse permissionsArticle Views81Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Identification of Nonlinear Parameter-Dependent Common-Structured models to accommodate varying experimental conditions and design parameter properties (2006)

This study considers the identification problem for a class of nonlinear parameter-varying systems associated with the following scenario: the system behaviour depends on some specifically prescribed parameter properties, which are adjustable. To understand the effect of the varying parameters, several different experiments, corresponding to different parameter properties, are carried out and different data sets are collected. The objective is to find, from the available data sets, a common parameter-dependent model structure that best fits the adjustable parameter properties for the underlying system. An efficient common model structure selection (CMSS) algorithm, called the extended forward orthogonal regression (EFOR) algorithm, is proposed to select such a common model structure. Several examples are presented to illustrate the application and the effectiveness of the new identification approach.
Structural Organization of the Microsomal Glutathione S-Transferase Gene (MGST1) on Chromosome 12p13.1–13.2 (2000)

The structure and regulation of the microsomal glutathione S-transferase gene (MGST1) are considerably more complex than originally perceived to be. The MGST1 gene has two alternative first exons and is located in the 12p13.1-13.2 region. Two other potential first exons were determined to be nonfunctional. The region between the functional first exons cannot direct transcription. Thus, one common promoter element directing transcription exists, and RNA splicing occurs such that only one of the first exons (containing only untranslated mRNA) is incorporated into each mRNA species with common downstream exons. MGST1 expression and regulation are therefore similar to those of other hepatic xenobiotic handling enzymes, which also produce mRNA species differing only in the 5'-untranslated regions to yield identical proteins. MGST1 was previously considered a "housekeeping" gene, as non-oxidant inducers had little effect on activity. However, the promoter region immediately upstream of the dominant first exon transcriptionally responds to oxidative stress. In this respect, MGST1 is similar to glutathione peroxidases that also transcriptionally respond to oxidative stress. The discovery that MGST1 utilizes alternative first exon splicing eliminates a problem with the first description of MGST1 cDNA in that it appeared that MGST1 expression was in violation of the ribosomal scanning model. The identification that the first exon originally noted is in fact a minor alternative first exon far downstream of the primary first exon eliminates this conundrum.
The Reaction of 4-Chloroquinoline 1-Oxide with Activated Acetylenes: Furo[3,2-c]quinolines (1978)

4-Chloroquinoline 1-oxide and ethyl phenylpropiolate in boiling toluene givearnixture of 2-and 3-keto-alkylated products as well as ethyl 2-phenylfuro[3,2-clquinoline- 3-carboxylate. With ethyl acetylenedicarboxylate only
EPPA: An Efficient and Privacy-Preserving Aggregation Scheme for Secure Smart Grid Communications (2012)

The concept of smart grid has emerged as a convergence of traditional power system engineering and information and communication technology. It is vital to the success of next generation of power grid, which is expected to be featuring reliable, efficient, flexible, clean, friendly, and secure characteristics. In this paper, we propose an efficient and privacy-preserving aggregation scheme, named EPPA, for smart grid communications. EPPA uses a superincreasing sequence to structure multidimensional data and encrypt the structured data by the homomorphic Paillier cryptosystem technique. For data communications from user to smart grid operation center, data aggregation is performed directly on ciphertext at local gateways without decryption, and the aggregation result of the original data can be obtained at the operation center. EPPA also adopts the batch verification technique to reduce authentication cost. Through extensive analysis, we demonstrate that EPPA resists various security threats and preserve user privacy, and has significantly less computation and communication overhead than existing competing approaches.
Les écrivains belges et l’Occupation: entre engagement et indifférence (2003)

info:eu-repo/semantics/published
CrowdProbe (2018)

Devices with integrated Wi-Fi chips broadcast beacons for network connection management purposes. Such information can be captured with inexpensive monitors and used to extract user behavior. To understand the behavior of visitors, we deployed our passive monitoring system---CrowdProbe, in a multi-floor museum for six months. We used a Hidden Markov Models (HMM) based trajectory inference algorithm to infer crowd movement using more than 1.7 million opportunistically obtained probe request frames. However, as more devices adopt schemes to randomize their MAC addresses in the passive probe session to protect user privacy, it becomes more difficult to track crowd and understand their behavior. In this paper, we try to make use of historical transition probability to reason about the movement of those randomized devices with spatial and temporal constraints. With CrowdProbe, we are able to achieve sufficient accuracy to understand the movement of visitors carrying devices with randomized MAC addresses.
Fast Compressive 3D Single-pixel Imaging (2016)

In this work, we demonstrate a modified photometric stereo system with perfect pixel registration, capable of reconstructing continuous real-time 3D video at ~8 Hz for 64 × 64 image resolution by employing evolutionary compressed sensing.
An antagonist of platelet-activating factor suppresses endotoxin-induced tumor necrosis factor and mortality in mice pretreated with carrageenan (1993)

We found that carrageenan (CAR), that is, sulfated polygalactose, can enhance both lipopolysaccharide (LPS)-induced tumor necrosis factor (TNF) production and the rate of lethality in mice (M. Ogata, S. Yoshida, M. Kamochi, A. Shigematsu, and Y. Mizuguchi, Infect. Immun. 59:679-683, 1991). It has been reported that platelet-activating factor (PAF) antagonists reduce the rate of mortality from endotoxin shock. However, there are few reports regarding the effect of PAF antagonists on TNF production. The aim of the present study is to examine the effect of TCV-309, a new PAF antagonist, on LPS-induced TNF production and mortality in mice pretreated with CAR. ddY mice (6 to 7 weeks old) were injected intraperitoneally with CAR (5 mg per mouse) and were then divided into two groups: mice treated with a PAF antagonist (TCV-309; Takeda Pharmaceutical Co.) and control mice. The mice treated with PAF antagonist received indicated doses of TCV-309 subcutaneously (s.c.) at 30 min before LPS injection, while the control mice received 1 ml of saline s.c. at the same time. All mice were stimulated by intravenous injection of LPS (50 micrograms per mouse) at 24 h after pretreatment with CAR. At intervals after injection of LPS, serum samples were obtained for a TNF assay in which cytotoxicity to L929 cells was measured. TCV-309 both significantly suppressed LPS-induced TNF production and reduced mortality in a dose-dependent manner. When TCV-309 was administered at 30 min before injection of LPS, the effect of TCV-309 on the suppression of TNF activity was at its peak. Treatment with TCV-309 (990 micrograms per mouse) s.c. significantly improved the survival rate after challenge with LPS compared with the survival rate of control mice. Although the 50% lethal dose of LPS was 15 micrograms per mouse for control mice, it increased to 102 micrograms per mouse for mice that were treated s.c. with TCV-309 (990 micrograms per mouse). Even in vitro, TCV-309 also inhibited LPS-induced TNF production in thioglycolate-elicited macrophages. It was concluded that PAF plays an important role in endotoxin-induced TNF production and mortality.