gebhart/patrepeval huggingface dataset:
Permeability of the cell wall of Mycobacterium smegmatis (1994)

The cell wall of Mycobacterium smegmatis mc2155 was shown to be an effective permeability barrier to hydrophilic compounds. Permeability coefficients to beta-lactams ranged from 10 x 10(-7) to 0.5 x 10(-7) cms-1. Cell wall proteins were solubilized with EDTA and Genapol and were tested for channel-forming activity by reconstitution into lipid bilayers. Proteins were able to induce a voltage-gated cation-selective channel. The mycobacterial porin channel appeared to be water-filled since the single-channel conductance followed the mobility sequence of hydrated ions in the aqueous phase. On the basis of the Renkin equation and the single-channel conductance, the channel diameter was estimated to be around 3 nm. Model calculations showed that cation selectivity may be caused by four negative point-charges at the channel mouth. The permeability properties of the cell wall of intact cells were in good agreement with those of the reconstituted channel. Negatively charged cephalosporins, cefamandole and cephalothin, diffused at a 10- to 20-fold lower rate than the zwitterionic cephaloridine. The mycobacterial porin represents a major hydrophilic pathway of the cell wall of M. smegmatis.
Effect of eye and body movement on augmented reality in the manufacturing domain (2012)

Understanding the eye and body movements required to perform large vehicle assembly tasks is important for developing a mobile support system for mechanics, and tracking user movements with regard to the surrounding environment is critical for designing a wearable Augmented Reality (AR) systems. This poster summarizes a study measuring the eye and body movements of mechanics performing assembly activities in a live manufacturing environment. It reviews our quantitative analysis of eye movements and qualitative analysis of body movements and describes the implications of this data in terms of the feasibility and potential utility of using a mobile AR application to support manufacturing. We found that the mechanics' eye movements ranged over a slightly larger field than the eye movements reported in previous research because of constraints imposed by some body positions required in manufacturing tasks.
Short Communication Tube-forming polychaetes enhance invertebrate diversity and abundance in sandy sediments of Mozambique, Africa (2011)

In marine soft-bottom systems, polychaetes can increase habitat complexity by constructing rigid tubes (e.g. several onuphid species) that contrast with  surrounding topographically flat sediments. These structures can provide  predation refuges and increase larval settlement and thereby increase the richness and abundance of fauna. We collected invertebrate samples from an  intertidal flat with low onuphid tube density (2.7 m –2 ) in Mozambique and document that more organisms (70 times higher mollusc abundances) and more  species (15 times more mollusc species) were found associated with solitary tubes of an onuphid polychaete compared with surrounding sand habitats. These results are in agreement with tube versus sand comparisons from soft-bottom systems in the North Atlantic where polychaete tube densities are often much higher. Keywords : habitat formation, onuphid polychaete, species richness, western Indian Ocean African Journal of Marine Science 2011, 33(2): 327–332
Exploiting Advanced Hydrogel Technologies to Address Key Challenges in Regenerative Medicine (2018)

Regenerative medicine aims to tackle a panoply of challenges from repairing focal damage to articular cartilage to preventing pathological tissue remodeling after myocardial infarction. Hydrogels are water-swollen networks formed from synthetic or naturally derived polymers and are emerging as important tools to address these challenges. Recent advances in hydrogel chemistries are enabling researchers to create hydrogels that can act as 3D ex vivo tissue models, allowing them to explore fundamental questions in cell biology by replicating tissues' dynamic and nonlinear physical properties. Enabled by cutting edge techniques such as 3D bioprinting, cell-laden hydrogels are also being developed with highly controlled tissue-specific architectures, vasculature, and biological functions that together can direct tissue repair. Moreover, advanced in situ forming and acellular hydrogels are increasingly finding use as delivery vehicles for bioactive compounds and in mediating host cell response. Here, advances in the design and fabrication of hydrogels for regenerative medicine are reviewed. It is also addressed how controlled chemistries are allowing for precise engineering of spatial and time-dependent properties in hydrogels with a look to how these materials will eventually translate to clinical applications.
Intelligent Temperature-Control of Drilling Fluid in Natural Gas Hydrate Formation by Nano-Silica/Modified n-Alkane Microcapsules (2021)

Inhibiting hydrate decomposition due to the friction heat generated by the drilling tools is one of the key factors for drilling hydrate formation. Since the existing method based on chemical inhibition technology can only delay the hydrate decomposition rate, a phase-change microcapsule was introduced in this paper to inhibit, by the intelligent control of the drilling fluid temperature, the decomposition of the formation hydrate, which was microencapsulated by modified n-alkane as the core material, and nano-silica was taken as the shell material. Scanning electron microscope (SEM), size distribution, X-ray diffraction (XRD), and Fourier transform infrared spectrometer (FT-IR) were utilized to characterize the structural properties of microcapsules. Differential scanning calorimetry (DSC) spectra displayed that the latent heat was 136.8 J/g in the case of melting enthalpy and 136.4 J/g in the case of solidification enthalpy, with an encapsulation efficiency of 62.6%. In addition, the prepared microcapsules also showed good thermal conductivity and reliability. By comparison, it was also proved that the microcapsules had good compatibility with drilling fluid, which can effectively control the temperature of drilling fluid for the inhibition of hydrate decomposition.
Decoding Multi-Class Motor Imagery and Motor Execution Tasks Using Riemannian Geometry Algorithms on Large EEG Datasets (2023)

The use of Riemannian geometry decoding algorithms in classifying electroencephalography-based motor-imagery brain-computer interfaces (BCIs) trials is relatively new and promises to outperform the current state-of-the-art methods by overcoming the noise and nonstationarity of electroencephalography signals. However, the related literature shows high classification accuracy on only relatively small BCI datasets. The aim of this paper is to provide a study of the performance of a novel implementation of the Riemannian geometry decoding algorithm using large BCI datasets. In this study, we apply several Riemannian geometry decoding algorithms on a large offline dataset using four adaptation strategies: baseline, rebias, supervised, and unsupervised. Each of these adaptation strategies is applied in motor execution and motor imagery for both scenarios 64 electrodes and 29 electrodes. The dataset is composed of four-class bilateral and unilateral motor imagery and motor execution of 109 subjects. We run several classification experiments and the results show that the best classification accuracy is obtained for the scenario where the baseline minimum distance to Riemannian mean has been used. The mean accuracy values up to 81.5% for motor execution, and up to 76.4% for motor imagery. The accurate classification of EEG trials helps to realize successful BCI applications that allow effective control of devices.
Fast Weather Simulation for Inverse Procedural Design of 3D Urban Models (2017)

We present the first realistic, physically based, fully coupled, real-time weather design tool for use in urban procedural modeling. We merge designing of a 3D urban model with a controlled long-lasting spatiotemporal interactive simulation of weather. Starting from the fundamental dynamical equations similar to those used in state-of-the-art weather models, we present a novel simplified urban weather model for interactive graphics. Control of physically based weather phenomena is accomplished via an inverse modeling methodology. In our results, we present several scenarios of forward design, inverse design with high-level and detailed-level weather control and optimization, and comparisons of our method against well-known weather simulation results and systems.
Creating and evolving software by searching, selecting and synthesizing relevant source code (2009)

When programmers develop or maintain software, they instinctively sense that there are fragments of code that other developers implemented somewhere, and these code fragments could be reused if found. In this paper, we propose a novel solution that addresses the fundamental questions of searching, selecting, and synthesizing (S <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> ) software based on the analysis of Application Programming Interface (API) calls as units of abstractions that implement high-level concepts (e.g., the API call EncryptData implements a cryptographic concept). This paper outlines the details behind S <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> , analyzes current challenges and describes evaluation plans.
A monolithic 14 bit D/A converter fabricated with a new trimming technique (DOT) (1984)

An electrical trimming technique for a heavily doped polysilicon resistor (DOT) has been successfully applied to the fabrication of a monolithic 14-bit D/A converter. The converter trimmed by DOT showed a nonlinearity error of less than 1/4 LSB, which means the converter substantially has 15-bit accuracy. Resistance post-trimming stability is greatly improved by introducing an excess trimming and restoration process in DOT, resulting in the achievement of a resistance stability of within /spl plusmn/0.01% of 100 years use at 100/spl deg/C.
The Preparation and Reactions of Diphenylphosphinous Chloride (1955)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Preparation and Reactions of Diphenylphosphinous ChlorideCarl Stuebe, W. M. LeSuer, and G. R. NormanCite this: J. Am. Chem. Soc. 1955, 77, 13, 3526–3529Publication Date (Print):July 1, 1955Publication History Published online1 May 2002Published inissue 1 July 1955https://pubs.acs.org/doi/10.1021/ja01618a030https://doi.org/10.1021/ja01618a030research-articleACS PublicationsRequest reuse permissionsArticle Views564Altmetric-Citations52LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Figure S2 from Polyunsaturated Fatty Acids from Astrocytes Activate PPARγ Signaling in Cancer Cells to Promote Brain Metastasis (2023)

&lt;p&gt;Figure S2 shows astrocytes facilitate the growth and survival of brain metastatic cancer cells.&lt;/p&gt;
Evidence for sequential utilization of fibronectin, vitronectin, and collagen during fibroblast‐mediated collagen contraction (2002)

Contraction plays a major role in wound healing and is inevitably mediated through the mechanical interaction of fibroblast cytoskeleton and integrins with their extracellular matrix ligands. Cell-matrix attachment is critical for such events. In human dermal fibroblasts most such interactions are mediated by the beta1-type integrins. This study investigated the role played by key components in this system, notably fibronectin, vitronectin, and integrin subcomponents alpha2 and alpha5, which recognize collagen and fibronectin. Inhibition of adhesion through these ligands was studied either by antibody blocking or with fibronectin and/or vitronectin depletion. Functional effects of inhibition were monitored as force generation in collagen-glycosaminoglycan (IntegraTM) sponges, over 20 hours using a culture force monitor. Dose and time-course inhibition studies indicated that initial attachment and force generation (approx. 0-5 hours postseeding) was through fibronectin receptors and this was followed by vitronectin ligand and receptor utilization (4 hours onward). Utilization of the collagen integrin subcomponent alpha2 appeared to be increasingly important between 6 and 16 hours and dominant thereafter. Additionally, there was evidence for functional interdependence between the three ligand systems fibronectin, vitronectin, and collagen. We propose that there is a short cascade of sequential integrin-ligand interactions as cells attach to, extend through, and eventually contract their matrix. (WOUND REP REG 2002;10:-408)
Supplementary Table 4 from Ganetespib (STA-9090), a Nongeldanamycin HSP90 Inhibitor, Has Potent Antitumor Activity in <i>In Vitro</i> and <i>In Vivo</i> Models of Non–Small Cell Lung Cancer (2023)

&lt;p&gt;PDF file, 294K, Ganetespib Biodistribution and Pharmacokinetic Parameters.&lt;/p&gt;
Attribute-Based Access Control with Efficient Revocation in Data Outsourcing Systems (2010)

Some of the most challenging issues in data outsourcing scenario are the enforcement of authorization policies and the support of policy updates. Ciphertext-policy attribute-based encryption is a promising cryptographic solution to these issues for enforcing access control policies defined by a data owner on outsourced data. However, the problem of applying the attribute-based encryption in an outsourced architecture introduces several challenges with regard to the attribute and user revocation. In this paper, we propose an access control mechanism using ciphertext-policy attribute-based encryption to enforce access control policies with efficient attribute and user revocation capability. The fine-grained access control can be achieved by dual encryption mechanism which takes advantage of the attribute-based encryption and selective group key distribution in each attribute group. We demonstrate how to apply the proposed mechanism to securely manage the outsourced data. The analysis results indicate that the proposed scheme is efficient and secure in the data outsourcing systems.
Diffuse large B-cell lymphoma of the colon with synchronous liver metastasis: a rare case report mimicking metastatic colorectal adenocarcinoma (2014)

Primary colonic lymphomas represent a rare minority among the colonic neoplasms. Their correct pre-operative identification is crucial for the design of treatment. This case highlights the difficulty in diagnosing of primary colonic lymphoma. To our knowledge, this is the first report of a colonic lymphoma presenting with a colonic mass and a synchronous liver metastasis.
Detecting and predicting visually induced motion sickness with physiological measures in combination with machine learning techniques (2022)

Visually induced motion sickness (VIMS) is a common sensation when using visual displays such as smartphones or Virtual Reality. In the present study, we investigated whether Machine Learning (ML) techniques in combination with physiological measures (ECG, EDA, EGG, respiration, body and skin temperature, and body movements) could be used to detect and predict the severity of VIMS in real-time, minute-by-minute. A total of 43 healthy younger adults (25 female) were exposed to a 15-minute VIMS-inducing video. VIMS severity was subjectively measured during the video using the Fast Motion Sickness Scale (FMS) as well as before and after the video using the Simulator Sickness Questionnaire (SSQ). Thirty-one participants (72%) experienced VIMS in the present study. Results showed that changes in facial skin temperature and body movement had the strongest relationship with VIMS. On a minute-by-minute basis, ML models revealed a medium correlation between the physiological measures and the FMS scores. An acceptable classification score distinguishing between sick and non-sick participants was found. Our findings suggest that physiological measures may be useful for measuring VIMS, but they are not a reliable standalone method to detect or predict VIMS severity in real-time.
Adenosine‐5'‐triphosphate‐sensitive single potassium channel in the atrioventricular node cell of the rabbit heart. (1984)

The patch-clamp method was applied to single atrioventricular (a.v.) node cells of the rabbit heart to study the characteristics of the K+ channel. When the electrode contained 5.4 mM-K+, depolarizations of the cell-attached patch membrane induced outward single channel currents characterized by burst-like openings; the open-state probability increased from 0.005-0.01 at -40 mV to 0.07-0.1 at +20 mV of membrane potential. The reversal potentials of the current at K+ concentrations of 5.4, 20 and 130 mM in the electrode agreed with those given by the Nernst equation, indicating that this channel is selective for K+ ions. The slope conductance of the channel decreased beyond 60-90 mV positive to the reversal potential (inward-going rectification). The conductance near the reversal potential increased with increasing K+ concentrations on either side of the membrane: from 31-32 pS at 5.4 mM-K+ to 41-42 pS at 20 mM-K+ on the outside, and from 19 pS at 90 mM-K+ to 29.3 pS at 130 mM-K+ on the inside. Superfusion of the cell with 5.4 mM-CN-, glucose-free Tyrode markedly increased the number of channel openings in the cell-attached patch. In the inside-out patch, application of 1 mM-adenosine-5'-triphosphate (ATP) at the inner surface of the patch membrane blocked reversibly the channel activity, while 1 mM-adenosine-5'-diphosphate (ADP) failed to block it. The conductance and kinetics of the channel were not modified by increasing the Ca2+ concentration from 10(-8) M to 5 X 10(-6) M on the inner side of the membrane, while a further increase in Ca2+ to 10(-4) M decreased the open-state probability. The probability density for the open time fitted well with an exponential distribution (time constant of 5.4 ms at 60 mV positive to the resting potential), while that for the closed time was separated into a fast and a slow component (time constants of 4.0 and 132.0 ms, respectively). The time constant of the slow component decreased significantly with depolarization in some preparations. However, neither the time constant of the fast component of the closed-time histogram nor that of the open-time histogram was voltage-dependent.
Image-based transformation of viewpoint and scene appearance (1997)

This thesis addresses the problem of synthesizing images of real scenes under threedimensional transformations in viewpoint and appearance. Solving this problem enables interactive viewing of remote scenes on a computer, in which a user can move a virtual camera through the environment and virtually paint or sculpt objects in the scene. It is demonstrated that a variety of three-dimensional scene transformations can be rendered on a video display device by applying simple transformations to a set of basis images of the scene. The virtue of these transformations is that they operate directly on images and recover only the scene information that is required in order to accomplish the desired effect. Consequently, they are applicable in situations where accurate three-dimensional models are difficult or impossible to obtain. A central topic is the problem of view synthesis, i.e., rendering images of a real scene from different camera viewpoints by processing a set of basis images. Towards...
Effect of Yogurt Containing Bifidobacterium longum BB536 on the Intestinal Environment, Fecal Characteristics and Defecation Frequenc (1997)

Yogurt containing Bifidobacterium longum BB536 (designated as Bifidus yogurt) was administered to adult volunteers and its effects on the intestinal environment with reference to fecal microflora, ammonia levels, fecal characteristics (color, consistency) and defecation frequency were examined. Bifidus yogurt was manufactured by fermenting milk with B. longum BB536, Streptococcus thermophilus STH-450 and Lactobacillus delbrueckii subsp. bulgaricus LBU-108. Standard yogurt manufactured using only S. thermophilus STH-450 and L. delbrueckii subsp. bulgaricus LBU-108 was used as the control diet. Eleven women volunteers were assigned as subjects to test the effects of Bifidus yogurt on the intestinal environment. Thirty-nine women volunteers were assigned as subjects to test the effects on fecal characteristics and defecation frequency. The volunteers were each administered 100 g of standard yogurt per day for two weeks. After a two-week interval period, each subject was administered 100 g of Bifidus yogurt per day for the subsequent test period. The period of administration of Bifidus yogurt was 2 weeks for testing effects on the intestinal environment and 3 weeks for testing effects on fecal characteristics and defecation frequency. The administration of Bifidus yogurt was effective to increase the number and relative percentage of fecal bifidobacteria significantly. The fecal ammonia concentration tended to decrease and fecal organic acid content tended to increase. The defecation frequency was significantly increased by Bifidus yogurt. The color of the feces changed to yellow and the consistency changed to soft. The administration of Bifidus yogurt was effective to improve the intestinal environment, fecal characteristics and defecation frequency.
Intracavity coherent addition of single high-order modes (2005)

We report on efficient intracavity coherent addition of several single high-order mode distributions in a multichannel laser resonator. The phase locking and coherent addition is achieved by using an intracavity interferometric beam combiner. The principle, configuration, and experimental results with pulsed Nd:YAG Laguerre-Gaussian TEM01 and TEM02 laser beam distributions are presented. The results reveal more than 95% combining efficiency with a nearly pure high-order mode output beam distribution in both free-running and Q-switched operation.