gebhart/patrepeval huggingface dataset:
Identification of three types of granules in neutrophils of ruminants. Ultrastructure of circulating and maturing cells. (1985)

The production of three populations of granules during maturation and their occurrence in the neutrophils of a number of ruminants is described. Bone marrow samples from cows, sheep, and goats were fixed, reacted for peroxidase, and examined by transmission electron microscopy. Granule formation was found to occur at three subsequent stages. As in other species including man, it begins with the production of peroxidase-positive granules and is concluded with the production of moderately dark-staining, peroxidase-negative granules of similar size. These two organelles have the characteristics of the azurophil or primary and specific or secondary granules of other species. At an intermediate stage, a different type of peroxidase-negative granule, the large granule, is formed. Its profile is round and markedly larger than those of azurophil and specific granules. The large granules initially have a loose, undulated membrane and fill gradually with matrix which in early forms consists of a central core. Fully developed large granules have a sharply defined membrane and a pale, very uniform content. The two types of peroxidase-negative granules can be distinguished by their sizes and times of formation and also by the appearance of their content which is more coarse and darker in the specific granules. Mature neutrophils from cows, goats, sheep, and an ibex were also examined. Two features are common to all cells viewed: the presence of three types of granules and the preponderance of the large granule population. The results of this study, together with evidence from cell fractionation experiments, suggest that the large granules are a characteristic property of the neutrophils of ruminants.
Use of the polymerase chain reaction (PCR) to detect monoclonality of B cell lymphoproliferative disorders (1991)

A technique has been developed using PCR to detect monoclonality of B-lymphoproliferative disorders. DNA was extracted from the blood, tissue and paraffin embedded sections by biochemical means or boiling. Forty cases of B-non Hodgkin’s lymphoma (NHL), 15 cases of T-NHL, 8 cases of chronic lymphocytic leukemia, 17 cases of reactive lymphadenopathy and 12 cases of various non-lymphocytic tumor were examined. Monoclonality of B-lymphocytes was detected in 86–92% of cases with B-lymphoproliferative diseases, but none in T-NHL, reactive disorders and non-lymphatic tumors. This technique provides a new molecular biologic method to diagnose malignant B-lymphoproliferative dicorders. It may be useful in Ig gene rearrangement study, differential diagnosis and retrospective investigation of lymphoproliferative disorders.
Isolation and Identification of Radical Scavenging and Tyrosinase Inhibition of Polyphenols from Tibouchina semidecandra L. (2010)

Phytochemical and bioactivity studies of the leaves and stem barks of Tibouchina semidecandra L. have been carried out. The ethyl acetate extract of the leaves yielded four flavonoid compounds, identified as quercetin, quercetin 3-O-α-l-(2''-O-acetyl) arabinofuranoside, avicularin, and quercitrin, while the stem barks gave one ellagitannin, identified as 3,3'-O-dimethyl ellagic acid 4-O-α-l-rhamnopyranoside. Evaluation of the antioxidative activity on the crude extracts and pure compounds by electron spin resonance (ESR) and ultraviolet-visible (UV-vis) spectrophotometric assays showed that the pure isolated polyphenols and the EtOAc extract possessed strong antioxidative capabilities. Quercetin was found to be the most active radical scavenger in DPPH-UV and ESR methods with SC(50) values of 0.7 μM ± 1.4 and 0.7 μM ± 0.6 μM, respectively, in the antioxidant assay. A combination of quercetin and quercitrin was tested for synergistic antioxidative capacity;, however, there was no significant improvement observed. Quercetin also exhibited strong antityrosinase activity with a percent inhibition of 95.0% equivalent to the positive control, kojic acid, in the tyrosinase inhibition assay.
The Periarteriolar Lymphocyte Sheath in Immunodeficiency T- or B-Lymphocyte Area? (1990)

In 153 patients with biopsy-proven primary systemic amyloidosis (AL), serum creatinine level correlated with median survival (creatinine less than or equal to 115 mumol/L [1.3 mg/dL], 2.56 months; creatinine greater than 115 mumol/L [1.3 mg/dL], 14.9 months; P = 0.007). The 24-hour urine total protein excretion was not correlated with survival. Patients who excreted monoclonal lambda light chains in the urine had an inferior survival (12 months) compared with those with kappa (30 months) or no monoclonal protein (35 months) in the urine (P = 0.01). The presence of lambda monoclonal protein was not associated with a higher median creatinine level. A monoclonal protein was detected in the urine in 76% of patients; when patients with more than 1 g of protein in the urine were studied, however, a monoclonal protein was detectable in 86%. The overall kappa-lambda ratio was 1:2.56, but as the urinary protein loss increased, the kappa-lambda ratio shifted to 1:4.7 for those with more than 3 g of protein in the urine.
WIP: Web Service Initiation Protocol for Multimedia and Voice Communication over IP (2006)

In this paper, we present WIP - Web service initiation protocol for multimedia and voice communication over IP. WIP is an entirely Web service based communication protocol, consisting of a set of Web service operations for initiating and establishing converged (e.g. multimedia, IM, voice, etc.) communication services over IP. It inherits the principle of separation signaling and media transmission of SIP (session initiation protocol); but it relies on a single Web service stack to provide a full featured communication signaling protocol. WIP opens a new paradigm of Web service based VoIP communication, which is extensible and can be easily integrated in end-to-end SOA solutions. The generic Web service approach used in WIP overcomes many limitations which would be otherwise difficult to achieve in non-Web service based communication methods used today. WIP is based on two-way, full duplex Web service interaction. The communication signaling establishment in WIP is through Web service interactions, and the media negotiation in WIP is modeled as a special Web service "event" subscription, which is fully extensible for various media needs. The signaling messages of WIP are encoded in the standard based SOAP message envelops which can be carried by multiple transport protocols, including HTTP. WIP supports both P2P (peer-to-peer) and B2B (back-to-back) broker mode communication services. A prototype research system has been implemented, and the results indicate that WIP, as a full Web service based communication protocol, is both feasible and advantageous
Nanoscale kinetics of amorphous calcium carbonate precipitation in H2O and D2O (2020)

Calcium carbonate (CaCO<sub>3</sub>) is one of the most well-studied and abundant natural materials on Earth. Crystallisation of CaCO<sub>3</sub> is often observed to proceed via an amorphous calcium carbonate (ACC) phase, as a precursor to more stable crystalline polymorphs such as vaterite and calcite. Despite its importance, the kinetics of ACC formation have proved difficult to study, in part due to rapid precipitation at moderate supersaturations, and the instability of ACC with respect to all other polymorphs. However, ACC can be stabilised under confinement conditions, such as those provided by a nanopipette. This paper demonstrates electrochemical mixing of a Ca<sup>2+</sup> salt (CaCl<sub>2</sub>) and a HCO<sub>3</sub><sup>-</sup> salt (NaHCO<sub>3</sub>) in a nanopipette to repeatedly and reversibly precipitate nanoparticles of ACC under confined conditions, as confirmed by scanning transmission electron microscopy (STEM). Measuring the current as a function of applied potential across the end of the nanopipette and time provides millisecond-resolved measurements of the induction time for ACC precipitation. We demonstrate that under conditions of electrochemical mixing, ACC precipitation is extremely fast, and highly pH sensitive with an apparent third order dependence on CO<sub>3</sub><sup>2-</sup> concentration. Furthermore, the rate is very similar for the equivalent CO<sub>3</sub><sup>2-</sup> concentrations in D<sub>2</sub>O, suggesting that neither ion dehydration nor HCO<sub>3</sub><sup>-</sup> deprotonation represent significant energetic barriers to the formation of ACC. Finite element method simulations of the electrochemical mixing process enable the supersaturation to be estimated for all conditions and accurately predict the location of precipitation.
Modulation of pain signal processing by electric acupoint stimulation: an electroencephalogram study. (2003)

These changes might reflect a modulation of brain activity by EAS in specific areas, which were in turn involved in modulation of certain aspects of pain-signal processing.
Effect of laser radiation on the gamma activity of aqueous salt solutions containing 152Eu (2019)

Abstract We report an experimental study of the effect of laser irradiation of aqueous salt solutions containing the 152 Eu isotope in the presence of nickel nanoparticles on the gamma activity of the isotope. Nickel nanoparticles are generated using laser ablation of the target in water and added to the radionuclide solution before irradiation. Two types of Nd : YAG lasers with a pulse duration of 10 ns and different repetition rates are used to irradiate the solutions. It is found that the 152 Eu activity as a result of repeated irradiation of solutions by a series of pulses decreases with each irradiation cycle. The obtained results are compared with data on the effect of maser radiation with a wavelength of 8 mm on the activity of the same isotope. Possible mechanisms of the effect of electromagnetic radiation on the 152 Eu gamma activity are discussed.
Resurrection of carbon dioxide as refrigerant in solar thermal absorption cooling systems (2023)

The existing air conditioning and cold storage systems use conventional compressor based systems, compelling more electricity and greenhouse gasses (GHG) emissions. The incumbent cooling system uses synthetic refrigerants (CFCs, HCFC, and HFCs) that outperform natural refrigerants but are banned or under time bared permission due to their harmful effects. The global community of (196 parties till 2017) has ratified Paris Accord to limit GHG emissions and use low Global Warming Potential (GWP) refrigerants, and after the ban on existing synthetic refrigerants, quested for suitable natural working fluids and retrofitting in the existing system. Among ASHRAE envisaged natural refrigerants, CO<sub>2</sub> has resurrected as an emerging refrigerant after the availability of high pressure technologies. The proposed design of solar assisted absorption chiller employing CO<sub>2</sub> as a heat transfer fluid for a commercial dwelling is simulated for a dwelling in the hot and humid, moderate and sun adverse region (Lahore, 31.5204° N, 74.3587° E) to assess the thermal properties of the proposed design. A thermal storage tank with immersed heat exchangers augmented to meet the intermittency of solar energy. A solar evacuated glass tube collector (EGTC) with U-shaped copper tubes is used to collect solar heat energy. Integration of renewable energy (RE) systems is inevitable due to the persistent energy crisis and climate change situations. Solar energy is a promising source of energy abundantly available in hot areas. CO<sub>2</sub> is a natural refrigerant that outperforms ASHRAE envisaged natural refrigerants due to the low critical point. A solar thermal cooling system employing a 35.2 kW absorption chiller driven via heat energy harnessed with EGTC using R-744 supported by an auxiliary furnace is simulated in a TRNSYS® Simulation environment. The simulated system covers the cooling requirements of a large three-room dwelling in Lahore, Pakistan. The proposed design comprises an R-744-based solar heating system combined with a hot water-fired absorption chiller. The results were dynamically simulated for the hot climate of Lahore, Pakistan, with average yearly maintained temperatures of 23 °C, 26 °C, and 21 °C for the three rooms and 0.21 solar fraction for the whole year.
<title>Interfacial contributions to magnetic thin film anisotropy arising from epitaxial growth processes in metal/semiconductor structures</title> (1994)

Modern thin film growth techniques have enabled the realization of low dimensional semiconductor heterostructures and hybrid metal/semiconductor structures with properties tailored for a variety of device applications. It has been empirically established, for example, that the net magnetic anisotropy exhibited by a simple metal epitaxial film on a semiconductor is strongly affected by the interactions at the metal/semiconductor interface, although the mechanisms have not been systematically addressed and remain an open issue. An understanding of these mechanisms is prerequisite to obtaining a fundamental description of anisotropy, and has significant implications for successful realization of spin sensitive device structures. We consider here how contributions to the net magnetic anisotropy arise from the formation of the interface and early stages of metal film growth. We suggest that these contributions originate in the initial metal adsorption sites and subsequent bond or site filling, and are strongly dependent on the semiconductor surface reconstruction. We consider specifically the cases of the epitaxial growth of Fe films on the various reconstructions of the ZnSe(001) and GaAs(001) surfaces, and attempt to interpret the net magnetic properties in light of the atomic structure of the film and interface.
A Case Study on MSME Schemes and Its Effectiveness from Bank Perspective (2020)

In India, many programmes didn’t reach the target small and medium enterprises (SMEs), as they lack the enthusiasm to innovate their product and services. A lot of officials and managers feel the waste of time and money for getting the scheme passed by the government. Various other factors such as bureaucratic apathy, corruption, red-tapism, inefficiency and lackluster attitude of government officials create hindrances in SMEs growth. A slew of schemes and sops for SMEs offered by the government, a majority didn’t utilize them due to lack of awareness and education about the schemes. The study made use of secondary data from different authenticated sources to draw meaningful conclusions. The effectiveness of schemes is scarcely been invented. Despite the above glitches, the SME sector’s growth is so obvious.
Novel three-octave, infrared hyperspectral imageing with a single multiwaveband FPA (2002)

The traditional approach for achieving hyperspectral imaging over a broad range of infrared (IR) wavelengths involves multiple focal plane arrays (FPAs), dispersive elements, and optical beamsplitters. It has been shown that the current state-of-the-art in dual-band infrared focal plane array (IRFPA) technology allows spectral imagery to be obtained in two wavebands simultaneously with a single FPA, therefore reducing cryo-cooler and power requirements. The new approach described here advances the capabilities of the current state-of-the-art one step further and achieves a spectrometer concept based on a tri-band IRFPA. The tri-band spectrometer concept would lead to spectral imagery collected simultaneously in the SWIR, MWIR, and LWIR spectral regions with high efficiency. To achieve this a unique characteristic of a dispersive grating, that of overlapping spectral orders, would be exploited to allow simultaneous focusing of three spectral bands onto the multi-waveband FPA, thereby creating co-registered spectral images. The capabilities of a multi-waveband FPA then allow integration of spectra independently in the various orders. In addition, spectral images would be perfectly registered both spatially and spectrally, a difficult prospect for the traditional approach. By providing hyperspectral imagery in the SWIR, MWIR, and LWIR spectral regions, we capture the bulk of reflected and thermally emissive target and background phenomenology, within the constraints of atmospheric transmission. The characteristics of a suitable tri-band FPA are derived on the basis of our modeling efforts.
Telephone Problem Solving for Service Members with Mild Traumatic Brain Injury: A Randomized, Clinical Trial (2016)

Mild traumatic brain injury (mTBI) is a common injury for service members in recent military conflicts. There is insufficient evidence of how best to treat the consequences of mTBI. In a randomized, clinical trial, we evaluated the efficacy of telephone-delivered problem-solving treatment (PST) on psychological and physical symptoms in 356 post-deployment active duty service members from Joint Base Lewis McChord, Washington, and Fort Bragg, North Carolina. Members with medically confirmed mTBI sustained during deployment to Iraq and Afghanistan within the previous 24 months received PST or education-only (EO) interventions. The PST group received up to 12 biweekly telephone calls from a counselor for subject-selected problems. Both groups received 12 educational brochures describing common mTBI and post-deployment problems, with follow-up for all at 6 months (end of PST), and at 12 months. At 6 months, the PST group significantly improved on a measure of psychological distress (Brief Symptom Inventory; BSI-18) compared to the EO group (p = 0.005), but not on post-concussion symptoms (Rivermead Post-Concussion Symptoms Questionnaire [RPQ]; p = 0.19), the two primary endpoints. However, these effects did not persist at 12-month follow-up (BSI, p = 0.54; RPQ, p = 0.45). The PST group also had significant short-term improvement on secondary endpoints, including sleep (p = 0.01), depression (p = 0.03), post-traumatic stress disorder (p = 0.04), and physical functioning (p = 0.03). Participants preferred PST over EO (p < 0.001). Telephone-delivered PST appears to be a well-accepted treatment that offers promise for reducing psychological distress after combat-related mTBI and could be a useful adjunct treatment post-mTBI. Further studies are required to determine how to sustain its effects. (Trial registration: ClinicalTrials.gov Identifier: NCT01387490 https://clinicaltrials.gov ).
A scalable, tunable qubit, based on a clean DND or grain boundary D-D junction (1999)

Unique properties of a ballistic DND or grain boundary D-D junction, including doubly degenerate ground state with tunable potential barrier between the "up" and "down" states and non-quantized spontaneous magnetic flux, make it a good candidate for a solid state qubit. The role of quantum "spin" variable is played by the sign of equilibrium superconducting phase difference on the junction, which is revealed in the direction of spontaneous supercurrent flow in equilibrium. Possibilities of design-specific simultaneous operations with several integrated qubits are discussed.
Development and evaluation of BN felt as separator materials (1980)

Electrode separators are being developed and evaluated for use in high-temperature Li-Al/MS secondary batteries. Boron nitride fabric has been used as the separator material in most Li-Al/MS cells fabricated thus far. However, BN felt separators are presently under development because they are potentially less expensive and more porous than the BN fabric separators. As a preliminary evaluation, the physical properties of various BN felts were determined. Subsequently, felts were also tested in experimental cells operated for extended periods (>1000 hr). The tests indicated that the BN felt is suitable for use in cells.
Application of the Generalized Variational Principle to Self-Similar Solutions for the Evolution of Star Clusters (1993)

Abstract A generalized variational method based on the concept of a “local potential” was used to solve the orbit- averaged Fokker-Planck equation for stellar systems. We applied this method to two self-similar models for the evolution of isotropic stellar systems in order to test the usefulness of the method. One of the two models is for the core collapse stage; the other is for the post-collapse stage. The solutions obtained by the variational method approximate the exact solutions fairly well, though a problem of numerical accuracy remains.
Primary Care, 2200 AD (1987)

Ad Libitum1 May 1987Primary Care, 2200 ADDARRON R. BROWN, M.D.DARRON R. BROWN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-106-5-785_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Excerpt"My interrogator sent me to you. It thinks I'm psychopregnant.""Why? How do you feel?""Well, I'm bloated, and the babies in the condensing vats look so cute . . .""But all women feel this way at times. Do you really think you're psychopregnant?""How do I know? That's why I'm here-to find out if it's just an alpha-2 burst or the real thing ...""Well, let's find out!"The psycho-obstetrician was worried today. Not only was he having that gnawing pain in his chest again, but this was the third woman in the past month who thought... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Rochester, New York PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1987Volume 106, Issue 5Page: 785-785KeywordsThorax Issue Published: 1 May 1987 PDF DownloadLoading ...
Analysis of defective delayed-type hypersensitivity in autoimmune mice bearing lpr gene. (1986)

Many functional defects of T-cells have been found in autoimmune prone, MRL/MpJ-lpr/lpr (MRL/lpr) mice. We examined the capacity of delayed-type hypersensitivity (DTH) induction and macrophage migration inhibition factor (MIF) production. MRL/lpr and C57BL/6J-lpr/lpr (B6/lpr) mice were tested for capacity of DTH by the footpad reaction to purified protein derivative of tuberculin (PPD) and lung granuloma formation after immunization with BCG-cell wall (BCGCW). In lpr mice, the ability to induce DTH against exogeneous antigenic stimulation decreased with age. The results show that the defect of DTH in lpr mice caused by deficiency of the MIF producing capacity of proliferated T-cells rather than suppressor cell activity for MIF production.