gebhart/patrepeval huggingface dataset:
Supplemental Ingestion of Collagen Peptide Suppresses Ultraviolet—induced Erythema―A Randomized Double—blind Placebo—controlled Study― (2014)

Objectives A randomized double︱blind placebo︱controlled trial was performed to examine the effects of oral supplementation with fish︱derived collagen peptide on human skin damage induced by ultraviolet irradiation. Methods Before and after ingestion of 5 g of collagen peptide or placebo for 4 weeks, ultraviolet irradiation at 1.5 minimal erythema dose was applied to the back skin of Japanese adult males aged 20︱59 years with skin photo typeⅡ or Ⅲ. Erythema（a＊value）and melanin （Mexameter value）were measured on days 1（irradiation day）, 4, and 8. The water content of the stratum corneum and trans︱epidermal water loss were determined on days 1, 4, 8, 11, and 15. Results Erythema increased evidently on day 4 and decreased on day 8, while melanin increased slightly on day 4 and evidently on day 8. No significant differences were observed between the collagen peptide group and the placebo group for erythema and melanin before or after ingestion. However, when a stratified statistical analysis was performed for subjects older than 30 years of age, significant suppression of erythema was detected on day 4 in the collagen peptide group after ingestion for 4 weeks. No significant changes were detected for the water content and trans︱epidermal water loss. No adverse side effects attributable to collagen peptide ingestion were observed. Conclusions The present results suggest that supplemental ingestion of fish︱derived collagen peptide has beneficial effects on human skin for suppressing erythema induced by ultraviolet irradiation, particularly in older subjects above 30 years of age.
Sodium-glucose cotransporter 2 inhibition in non-diabetic kidney disease (2021)

There exists strong rationale for SGLT2 inhibition to be incorporated into standard of care for appropriate groups of patients with nondiabetic kidney disease.
Optimum Directivity Patterns for Linear Point Arrays (1953)

The sharpest major lobe of a directivity pattern due to a linear array of equally-spaced point elements is achieved when the elements are excited in such a manner that all minor lobes in the pattern have the same relative amplitude. Methods of producing such equal-minor-lobe patterns originally given in the radio literature by C. L. Dolph and by H. J. Riblet are summarized briefly in this paper. In particular, the synthesis method indicated by Riblet is described in general terms, and the effect of the element spacing is discussed in detail. Included in this discussion is the subject of super-directivity. Results of numerical calculations based on these methods are presented as families of curves showing the relationships existing among angular width of the major lobe, relative amplitude of the equal minor lobes, directivity index, and number and spacing of the elements in the array for 5–13 odd numbers of elements. In addition, the synthesis methods are extended to compensated, or steered, arrays.
Purification of the T lymphocyte growth factor interleukin-2 from culture media of human peripheral blood leukocytes (buffy coats) (1984)

Interleukin 2 was purified 100 000-fold to apparent homogeneity from the supernatants of mitogen-stimulated human blood leukocytes. A sequence of three purification steps was used: affinity chromatography on the bound dye cibacron blue, gel filtration on Ultrogel AcA44, and reversed-phase high-performance liquid chromatography on hexyl phase. The resulting interleukin 2 had a specific activity of 2 X 10(6) U/mg protein, and was free of pyrogenicity in the rabbit test. The final purification product showed two bands in sodium dodecyl sulfate/polyacrylamide gels with apparent molecular masses of 15 kDa and 17 kDa respectively. Both bands were biologically active.
Evolving Humanoid Robot Motions Based on Gene Regulatory Network (2019)

Motion generation for humanoid robots is a hard task because of the complex and unstable structures. We solve this task using MONGERN which is a method to generate robot motions based on GRN with an evolutionary approach. MON GERN does not require any calculation of dynamic properties but can generate suitable motions for robots. In this research, we tried to obtain three realistic motions in the simulator called Webots to show the robustness and effectiveness of MONGERN. The motions are trap motion in soccer, bracing motion for a predictable impact and continuous skating motion. In our experiments, we were able to obtain desirable motions which include unexpected motions. We were able to observe the robust and flexible motion-generation ability of this method. In the case of skating motion, it has been successfully applied to a real robot, KHR3HV designed by Kondo-Science. These experiments imply that the method can be useful in generating complex motions even in the real world.
Kerben (2003)

Als Kerben wirken alle plötzlichen Querschnittsänderungen in Bauteilen. Häufig sind diese konstruktiv notwendig, z. B. als Lagersitz, in Form von Passfedernuten, als Sprengringaufnahmen, Bohrungen oder Gewinde für Anschlüsse. Andererseits können Kerben auch durch die Fertigung oder den Betrieb entstehen, beispielsweise als Gusslunker, Drehriefen oder Macken. Sie führen zu Spannungskonzentrationen und können deshalb vorzeitiges Versagen verursachen, sofern sie bei der Bauteilauslegung nicht berücksichtigt werden. Die Aufgabe der in diesem Abschnitt behandelten Theorien ist es, die Auswirkungen der Kerben auf die Beanspruchung des Werkstoffs abzuschätzen und so ein Werkzeug zur Auslegung von Bauteilen mit Kerben zur Verfügung zu stellen.
Prevalence and Predictors of BRCA1 and BRCA2 Mutations in a Population-Based Study of Breast Cancer in White and Black American Women Ages 35 to 64 Years (2006)

Although well studied in families at high-risk, the roles of mutations in the BRCA1 and BRCA2 genes are poorly understood in breast cancers in the general population, particularly in Black women and in age groups outside of the very young. We examined the prevalence and predictors of BRCA1 and BRCA2 mutations in 1,628 women with breast cancer and 674 women without breast cancer who participated in a multicenter population-based case-control study of Black and White women, 35 to 64 years of age. Among cases, 2.4% and 2.3% carried deleterious mutations in BRCA1 and BRCA2, respectively. BRCA1 mutations were significantly more common in White (2.9%) versus Black (1.4%) cases and in Jewish (10.2%) versus non-Jewish (2.0%) cases; BRCA2 mutations were slightly more frequent in Black (2.6%) versus White (2.1%) cases. Numerous familial and demographic factors were significantly associated with BRCA1 and, to a lesser extent, BRCA2 carrier status, when examined individually. In models considering all predictors together, early onset ages in cases and in relatives, family history of ovarian cancer, and Jewish ancestry remained strongly and significantly predictive of BRCA1 carrier status, whereas BRCA2 predictors were fewer and more modest in magnitude. Both the combinations of predictors and effect sizes varied across racial/ethnic and age groups. These results provide first-time prevalence estimates for BRCA1/BRCA2 in breast cancer cases among understudied racial and age groups and show key predictors of mutation carrier status for both White and Black women and women of a wide age spectrum with breast cancer in the general population.
Quantitative artifact reduction and pharmacologic paralysis improve detection of EEG epileptiform activity in critically ill patients (2022)

In the appropriate setting, both AR and paralysis facilitate identification of epileptiform activity in critically ill patients.
Unsupervised Learning of Sentence Embeddings Using Compositional n-Gram Features (2018)

Matteo Pagliardini, Prakhar Gupta, Martin Jaggi. Proceedings of the 2018 Conference of the North American Chapter of the Association for Computational Linguistics: Human Language Technologies, Volume 1 (Long Papers). 2018.
Antiphospholipid syndrome: a review and update for the dermatologist. (2006)

Antiphospholipid syndrome (APS) is a hypercoagulable disorder that results in vascular thrombosis. The symptoms are numerous and depend on the size and location of the vessels involved. Patients with this condition can have significant morbidity and occasionally mortality. It is important for dermatologists to be knowledgeable about APS because a large percentage of patients with this condition will present with dermatologic manifestations. If diagnosed and treated early, patients can be spared the consequences of this serious disease.
Organisational culture: variation across hospitals and connection to patient safety climate (2010)

Hospitals vary in organisational culture, and the type of culture relates to the safety climate within the hospital. In combination with prior studies, these results suggest that a healthcare organisation's culture is a critical factor in the development of its patient safety climate and in the successful implementation of quality improvement initiatives.
The Effect of Interruption Modality on Primary Task Resumption (2008)

The majority of empirical papers investigating the effect of interruption modality on primary task resumption have been grounded in Multiple Resource theory; this theory stresses the benefits of cross-modal information presentation. Alternatively, Altmann and Trafton's (2002) Memory for Goals theory suggests that maintaining an association between the suspended primary task goal and relevant environmental cues is critical to the task resumption process. Using reaction time and eye movement measures, the theoretical predictions of these two frameworks were empirically examined to determine whether interruption modality influences primary task resumption.
Cu pattern etching by oxygen gas cluster ion beams with acetic acid vapor (2014)

Halogen free and low-temperature Cu etching was carried out using a gas cluster ion beam (GCIB) with acetic acid vapor. A very shallow Cu surface was oxidized by oxygen GCIB (O2-GCIB). Simultaneously, reactions between CuO and acetic acid occurred, and reaction products were desorbed by local heating of O <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> -GCIB irradiation. Thus, Cu etching at a low-temperature (<60 °C) was achieved. From cross-sectional images of Cu pattern with line width of 100 nm, anisotropic Cu etching was carried out with this technique.
Quasi-resonant and quasi-phase-matched nonlinear second-order phenomena in whispering-gallery resonators (2012)

Recently achieved radial poling of whispering-gallery resonators (WGRs) strongly extends the capabilities of tailoring the second-order nonlinear phenomena, such as second-harmonic generation and optical parametric oscillation, and transferring them to the range of low-power continuous-wave light sources. Owing to discreteness of the frequency spectrum, the resonance and phase-matching conditions for interacting waves cannot be fulfilled simultaneously in WGRs in the general case. Using Yariv&#x2019;s generic approach to the description of WGR phenomena, we analyze two closely related issues: the possibilities to achieve the resonant and phase-matching conditions using the temperature tuning and the impact of detunings and phase mismatches on the nonlinear transformation efficiencies. It is shown that the radial poling provides important necessary conditions for the subsequent fine tuning to the nonlinear resonances. The requirements to the temperature tuning, as exemplified by the case of lithium niobate, are substantially dependent on the nonlinear process in question, the actual wavelength range, and the pump intensity.
Secure roaming and infrastructure sharing for multi-operator WMNs (2013)

Wireless mesh networks consist of a wireless infrastructure of mesh routers which are connected to the Internet via mesh gateways. While previous security research in the area mainly focused single-operator networks, this paper proposes a comprehensive security architecture for multi-operator wireless mesh networks. Our proposal allows for a secure deployment of infrastructure components (routers and gateways) as well as mesh client. The multi-operator support of our architecture does not only cover mesh client roaming, but also the deployment of infrastructure components of one operator in the administrative domain of the other operator. Our architecture is thus - to the best of our knowledge - the first to support secure infrastructure sharing between operators. Note that our solution is based on open standards and protects traffic generated by mesh clients from insider attackers such as compromised mesh routers, mesh routers operated by malicious operators, and curious or malicious routing mesh clients.
Attrition Resistant Iron-Based Fischer-Tropsch Catalysts. (1997)

The Fischer-Tropsch (F-T) reaction provides a way of converting coal-derived synthesis gas (CO and H{sub 2}) to liquid fuels. Since the reaction is highly exothermic, one of the major problems in control of the reaction is heat removal. Recent work has shown that the use of slurry bubble column reactors (SBCRs) can largely solve this problem. Iron-based (Fe) catalysts are preferred catalysts for F-T when using low CO/H{sub 2} ratio synthesis gases derived from modern coal gasifiers. This is because in addition to reasonable F-T activity, the F-T catalysts also possess high water gas shift (WGS) activity. However, a serious problem with the use of Fe catalysts in a SBCR is their tendency to undergo attrition. This can cause fouling/plugging of downstream filters and equipment, making the separation of catalyst from the oil/wax product very difficult if not impossible, and results in a steady loss of catalyst from the reactor. The objectives of this research are to develop a better understanding of the parameters affecting attrition resistance of Fe F-T catalysts suitable for use in SBCRs and to incorporate this understanding into the design of novel Fe catalysts having superior attrition resistance. Catalyst preparations will be based on the use of spray drying and will be scalable using commercially available equipment. The research will employ among other measurements, attrition testing and F-T synthesis, including long duration slurry reactor runs in order to ascertain the degree of success of the various preparations. The goal is to develop an Fe catalyst which can be used in a SBCR having only an internal filter for separation of the catalyst from the liquid product, without sacrificing F-T activity and selectivity.
A priesthood renewed : modernity and traditionalism in a South Indian temple (2003)

Figures and Tables ix Preface xi Note on Transliteration xv Key to Figures 1 and 2 xvii Chapter One: The Priests and the Minakshi Temple's Renovation Ritual 1 Chapter Two: Rights,Duties,and Work 19 Chapter Three: Family and Domestic Life 57 Chapter Four: The Agamas and Priestly Education 80 Chapter Five: Religious Politics and the Priests 114 Chapter Six: Modernity,Traditionalism,and the State 152 Notes 169 Glossary 191 Bibliography 195 Index 205
Beyond Quantitative Proteomics:  Signal Enhancement of the a1 Ion as a Mass Tag for Peptide Sequencing Using Dimethyl Labeling (2004)

Stable isotope-based dimethyl labeling that produces a dimethyl labeled terminal amine or a monomethylated proline N-terminus by reductive methylation (Anal. Chem. 2003, 75, 6843-6852) was reported as a promising strategy for global quantitative proteomics because of the simplicity of the process and its fast and complete reaction. This labeling strategy provides a signal enhancement for the produced a1 ions, which are usually hard to detect among most of the nonderivatized fragments. To assist peptide sequencing, in this study, the enhanced a1 ion produced under either collision induced dissociation (CID) or post source decay (PSD) modes was further characterized and applied as a mass tag for fingerprinting the identity of N-terminal amino acid. On the basis of the analysis of standard peptides, tryptic digests of hemoglobin and cell lysates, it was proved that such signal enhancement occurred to a1 ions derived from all 20 of the amino acids residues and this phenomenon was explained based the formation of stable quaternary immoniun ions. Accurate determination of a1 ions was shown to increase the chance for peptide de novo sequencing and also provided higher confidence in the scores obtained when identifying a protein through database searching. In addition, the a1 ion was further demonstrated to be used as a universal tag for precursor ion scan in a Q-TOF instrument, leading to a greater number of peptide ions sequenced. Combined with the capability for differential quantitation, the stable isotope-based dimethyl labeling increases the usefulness of the labeling method for MS-based proteomics.
Demonstration of Santoku (2015)

Advanced analytics is a booming area in the data management industry and a hot research topic. Almost all toolkits that implement machine learning (ML) algorithms assume that the input is a single table, but most relational datasets are not stored as single tables due to normalization. Thus, analysts often join tables to obtain a denormalized table. Also, analysts typically ignore any functional dependencies among features because ML toolkits do not support them. In both cases, time is wasted in learning over data with redundancy. We demonstrate Santoku , a toolkit to help analysts improve the performance of ML over normalized data. Santoku applies the idea of factorized learning and automatically decides whether to denormalize or push ML computations through joins. Santoku also exploits database dependencies to provide automatic insights that could help analysts with exploratory feature selection. It is usable as a library in R, which is a popular environment for advanced analytics. We demonstrate the benefits of Santoku in improving ML performance and helping analysts with feature selection.
Electron Spin Resonance Study of X-Irradiated Single Crystals of Di-n-butyl Oxalate–Urea and Di-n-butyl Malonate–Urea Inclusion Compounds (1970)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Allen A. Lai, G. Bruce Birrell, O. Hayes Griffith; Electron Spin Resonance Study of X‐Irradiated Single Crystals of Di‐n‐butyl Oxalate–Urea and Di‐n‐butyl Malonate–Urea Inclusion Compounds. J. Chem. Phys. 1 December 1970; 53 (11): 4399–4400. https://doi.org/10.1063/1.1673956 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioThe Journal of Chemical Physics Search Advanced Search |Citation Search
Dynamic Load Analysis and Optimization of Connecting Rod (2004)

ii ACKNOWLEDGEMENTS iv TABLE OF CONTENTS v LIST OF TABLES viii LIST OF FIGURES x NOMENCLATURE xx
Anionic Extraction for Efficient Recovery of Biobased 2,3‐Butanediol—A Platform for Bulk and Fine Chemicals (2017)

2,3-Butanediol (BDO) presents a promising platform molecule for the synthesis of basic and fine chemicals. Biotechnological production of BDO from renewable resources with living microbes enables high concentrations in the fermentation broth. The recovery of high-boiling BDO from an aqueous fermentation broth presents a subsequent challenge. A method is proposed for BDO isolation based on reversible complexation with phenylboronate in an anionic complex. BDO can be recovered by back-extraction into an acidic solution. The composition of the extracted species was determined by NMR spectroscopy, MS, and GC-MS methods. The conditions of extraction and back-extraction were optimized by using commercial BDO and finally applied to different fermentation broths. Up to 72-93 % BDO can be extracted and up to 80-90 % can be back-extracted under the optimized conditions. Purified bio-BDO was used in the presence of sulfuric acid for the synthesis of methyl ethyl ketone, an established organic solvent and discussed tailor-made biofuel.
Structure-Guided Redesign Increases the Propensity of HIV Env To Generate Highly Stable Soluble Trimers (2015)

HIV-1 displays unprecedented global diversity circulating in the human population. Since the envelope glycoprotein (Env) is the target of neutralizing antibodies, Env-based vaccine candidates that address such diversity are needed. Soluble well-ordered Env mimics, typified by NFL and SOSIP trimers, are attractive vaccine candidates. However, the current designs do not allow most Envs to form well-ordered trimers. Here, we made design modifications to increase the propensity of representatives from two of the major HIV subtypes to form highly stable trimers. This approach should be applicable to other viral Envs, permitting the generation of a repertoire of homogeneous, highly stable trimers. The availability of such an array will allow us to assess if sequential or cocktail immune strategies can overcome some of the vaccine challenges presented by HIV diversity.
Autonomous multilateral debridement with the Raven surgical robot (2014)

Autonomous robot execution of surgical sub-tasks has the potential to reduce surgeon fatigue and facilitate supervised tele-surgery. This paper considers the sub-task of surgical debridement: removing dead or damaged tissue fragments to allow the remaining healthy tissue to heal. We present an autonomous multilateral surgical debridement system using the Raven, an open-architecture surgical robot with two cable-driven 7 DOF arms. Our system combines stereo vision for 3D perception with trajopt, an optimization-based motion planner, and model predictive control (MPC). Laboratory experiments involving sensing, grasping, and removal of 120 fragments suggest that an autonomous surgical robot can achieve robustness comparable to human performance. Our robot system demonstrated the advantage of multilateral systems, as the autonomous execution was 1.5× faster with two arms than with one; however, it was two to three times slower than a human. Execution speed could be improved with better state estimation that would allow more travel between MPC steps and fewer MPC replanning cycles. The three primary contributions of this paper are: (1) introducing debridement as a sub-task of interest for surgical robotics, (2) demonstrating the first reliable autonomous robot performance of a surgical sub-task using the Raven, and (3) reporting experiments that highlight the importance of accurate state estimation for future research. Further information including code, photos, and video is available at: http://rll.berkeley.edu/raven.
STATISTICAL CHARACTERIZATION OF INTERMITTENT FAULTS IN DIGITAL SYSTEMS. (1800)

SmMARY In this paper, the problem of characterizing the stochastic behavior of intermittent faults is considered. Three analytical models for intermittent faults in digital systems are discussed. First model assumes that the intermittent faults can be modeled as a renewal process. The second model is a finite-state Narkovmodel. Finally, in the third model the fault-free interval between two intermittent faults is considered and the intermittent fault process is characterized in terms of these fault-free i ntervals. It is expected that these models will find a pplication in the prediction of performance of detection procedures for intermittent faults.