gebhart/patrepeval huggingface dataset:
Green synthesis of silver nanoparticles from purple acid phosphatase apoenzyme isolated from a new sourceLimonia acidissima (2015)

Green synthesis of nanoparticles is regarded as a safe and non-toxic process whereas conventional synthesis using chemical methods produces toxic substance. This study provides a novel insight for enzymatic synthesis method of silver nanoparticles using purple acid phosphatase, isolated from Limonia acidissima (wood apple) as a new source and used in the synthesis of silver nanoparticles. Stable silver nanoparticles were produced by sonochemical method using apoenzyme as a stabilising and capping agent and were characterised by various physicochemical techniques like UV–Visible spectroscopy, Fourier-transform infrared, X-ray diffraction and transmission electron microscopy. X-ray study shows that nanoparticles are composed of silver and silver oxide. The synthesised nanoparticles exhibited excellent antimicrobial activity against Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus.
Technological Applications in the Assessment of Acquired Neurogenic Communication and Swallowing Disorders in Adults (1999)

The role of technology is expanding rapidly in many aspects of the diagnostic process with patients who have neurogenic communication and swallowing disorders. In this article we discuss a broad selection of technological tools that enhance a wide range of diagnostic tasks, such as taking case histories, administering and scoring tests, performing acoustic, physiologic, cognitive, and linguistic analyses, making normative comparisons, profiling diagnostic results, and making diagnostic decisions. Clinicians are encouraged to scrutinize the relative value of all diagnostic tools to maintaining the quality of service. An appendix includes information for contacting vendors and manufacturers of the products discussed.
Easy and efficient one-pot synthesis of pyrazolo[1,5-c]quinazolines under mild copper-catalyzed conditions (2012)

An easy and efficient method has been developed for the synthesis of pyrazolo[1,5-c]quinazolines via one-pot two-step reactions of readily available substituted 1-(2-halophenyl)-3-akylprop-2-yn-1-ones, hydrazine hydrochloride and amidine hydrochlorides under mild conditions, and the corresponding pyrazolo[1,5-c]quinazolines were obtained in good to excellent yields. The novel method affords a new strategy for the construction of diverse and useful poly N-heterocyclic compounds.
Recurrent Neural Network for Text Classification with Multi-Task Learning (2016)

Neural network based methods have obtained great progress on a variety of natural language processing tasks. However, in most previous works, the models are learned based on single-task supervised objectives, which often suffer from insufficient training data. In this paper, we use the multi-task learning framework to jointly learn across multiple related tasks. Based on recurrent neural network, we propose three different mechanisms of sharing information to model text with task-specific and shared layers. The entire network is trained jointly on all these tasks. Experiments on four benchmark text classification tasks show that our proposed models can improve the performance of a task with the help of other related tasks.
Augmented Reality for Teaching Science Vocabulary to Postsecondary Education Students With Intellectual Disabilities and Autism (2015)

The purpose of this study was to examine the use of an emerging technology called augmented reality to teach science vocabulary words to college students with intellectual disability and autism spectrum disorders. One student with autism and three students with an intellectual disability participated in a multiple probe across behaviors (i.e., acquisition of science vocabulary words) design. Data were collected on each student's ability to define and label three sets of science vocabulary words (i.e., bones, organs, and plant cells). The results indicate that all students acquired definition and labeling knowledge for the new science vocabulary terms. Results are discussed in the context of applying universal design principles with emerging technologies to create authentic opportunities for students with intellectual disabilities and autism spectrum disorders to learn science vocabulary. (Keywords: augmented reality, autism, intellectual disability, science vocabulary, universal design for learning)
Embryonic stem cell differentiation requires full length Chd1 (2015)

The modulation of chromatin dynamics by ATP-dependent chromatin remodeling factors has been recognized as an important mechanism to regulate the balancing of self-renewal and pluripotency in embryonic stem cells (ESCs). Here we have studied the effects of a partial deletion of the gene encoding the chromatin remodeling factor Chd1 that generates an N-terminally truncated version of Chd1 in mouse ESCs in vitro as well as in vivo. We found that a previously uncharacterized serine-rich region (SRR) at the N-terminus is not required for chromatin assembly activity of Chd1 but that it is subject to phosphorylation. Expression of Chd1 lacking this region in ESCs resulted in aberrant differentiation properties of these cells. The self-renewal capacity and ESC chromatin structure, however, were not affected. Notably, we found that newly established ESCs derived from Chd1(Δ2/Δ2) mutant mice exhibited similar differentiation defects as in vitro generated mutant ESCs, even though the N-terminal truncation of Chd1 was fully compatible with embryogenesis and post-natal life in the mouse. These results underscore the importance of Chd1 for the regulation of pluripotency in ESCs and provide evidence for a hitherto unrecognized critical role of the phosphorylated N-terminal SRR for full functionality of Chd1.
Evaluation of novel biodegradable three‐armed‐ and hyper‐branched tissue adhesives in a meniscus explant model (2017)

Current treatment methods to repair meniscal tears do not bring fully satisfactory results. Tissue adhesives are considered promising alternatives, since they are easy to apply and cause minimal tissue trauma. The first aim of this study was to analyze the adhesive properties of and tissue response to two recently developed biodegradable block copolymeric three-armed- and hyper-branched tissue adhesives. The second aim was to investigate if tissue surface modification with collagenase improves the attachment of the adhesives and increases the healing potential of the tissue. Cylindrical explants were harvested from bovine menisci. The central core of the explants was removed and glued back into the defect, with or without incubation in collagenase solution prior to gluing, using one of the novel glues, Dermabond® or fibrin glue. The repair constructs were cultured in vitro for 1 and 28 days. Adhesion tests and histology were performed to analyze the effects of the glue in combination with the additional treatment. The adhesive strength of the novel glues was 40-50 kPa, which was significantly higher than that of fibrin glue (15 kPa). Cells were present in direct contact with the glues, and the tissue remained vital during the whole culture period. Increased cellularity around the tear in the collagenase treated explants was observed after 1 day. The two newly developed tissue adhesives are attractive materials to be used for repair of meniscal tears. The beneficial influence of collagenase treatment in treating meniscal tears with glues still needs to be confirmed in more clinical relevant studies. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 1405-1411, 2017.
Short survival of phosphatidylserine-exposing red blood cells in murine sickle cell anemia (2001)

Several transgenic murine models for sickle cell anemia have been developed that closely reproduce the biochemical and physiological disorders in the human disease. A comprehensive characterization is described of hematologic parameters of mature red blood cells, reticulocytes, and red cell precursors in the bone marrow and spleen of a murine sickle cell model in which erythroid cells expressed exclusively human alpha, gamma, and betaS globin. Red cell survival was dramatically decreased in these anemic animals, partially compensated by considerable enhancement in erythropoietic activity. As in humans, these murine sickle cells contain a subpopulation of phosphatidylserine-exposing cells that may play a role in their premature removal. Continuous in vivo generation of this phosphatidylserine-exposing subset may have a significant impact on the pathophysiology of sickle cell disease.
Shortening replacement by emulsion and foam template hydroxypropyl methylcellulose (HPMC)-based oleogels in puff pastry dough. Rheological and texture properties (2023)

Shortening plays an essential function in the formulation of sweet laminated bakery products, but has a potential health risk due to their high percentage of saturated fatty acids. In this paper, the feasibility of hydroxypropyl methylcellulose (HPMC) oleogels prepared with emulsion template (ET) and foam template (FT) approaches as fat sources in a puff pastry dough was investigated. Spreadability and thermal properties of control shortening, 100% ET and FT oleogels and shortening/oleogel (50/50) blends were measured. The different systems were applied as the fat source in a puff pastry dough, and their effect on rheological and texture properties was investigated. Results showed that partial replacement of shortening with oleogels could significantly decrease the firmness values (from 115 to 26 N) (P < 0.05) and increased the spreadability of shortening. The methodology to prepare the oleogel (FT or ET) also significantly affected the texture parameters. FT blends had the highest spreadability with significantly lower firmness values and area under the curve. Thermal values showed that both oleogels could slightly increase the melting point of shortening from 47 to 50 °C. The replacement of shortening with oleogel decreases the viscoelasticity of puff pastry dough and increases its thermal stability but does not significantly change dough viscoelasticity in the shortening/oleogel mixture. These results indicated that both oleogels have promising potential to replace shortening in puff pastry dough formulations, but the ET oleogel showed a more similar behavior to the control shortening than the FT oleogel.
The combination of the histone-deacetylase inhibitor trichostatin A and gemcitabine induces inhibition of proliferation and increased apoptosis in pancreatic carcinoma cells (2007)

The prognosis of advanced pancreatic cancer is poor. Established chemotherapy shows only limited efficacy and significant side effects. We investigated how far a combination of trichostatin A (TSA) and gemcitabine synergizes to inhibit proliferation and promotion of apoptosis of pancreatic adenocarcinoma cells in vitro. The human pancreatic carcinoma cells YAPC, DANG and Panc-89 and primary human foreskin fibroblasts as non-malignant controls were cultured under standardized conditions and incubated with gemcitabine und TSA alone (10(-4) to 10(-8) M) or together (10(-6) to 10(-7) M). After 24-72 h the apoptotic rate was analyzed by flow cytometry (propidium iodide, FACS). DNA-synthesis was assessed using bromodeoxyuridine (BrdU) incorporation. Protein was separated for Western blotting against caspase-3 and -8, p21, bax and bcl-2. The combination of TSA und gemcitabine leads to better pro-apoptotic effects than the employment of single substances. Bcl-2, a mitochondrial protein, which protects against apoptosis, was not expressed. Bax, an apoptosis inducing protein, which destabilizes the mitochondrial membrane potential, was increasingly expressed. Combination of TSA and gemcitabine shows promise for treatment of pancreatic cancer in vivo.
Modelling Bifacial Solar Energy Yield for Single-Axis Tracked Systems with Racking (2019)

This paper presents a bifacial PV energy yield simulation tool with highly-parameterized optical and electrical models. The resulting detailed irradiance profiles provide insight into the effects of rack shading. Horizontal parallel wiring architecture of cells in the module is found to mitigate nonuniform rear irradiance caused by torque tube shading in a single-axis tracked system for representative cloudy and clear days. Low cell shunt resistance is shown to amplify bifacial gain during low irradiance hours. Annual energy yield predictions for fixed and tracked bifacial PV systems for Ottawa, ON are also presented.
In Situ Environmental Transmission Electron Microscopy of Ice Nucleation (2015)

Journal Article In Situ Environmental Transmission Electron Microscopy of Ice Nucleation Get access Lyle M Gordon, Lyle M Gordon Environmental Molecular Spectroscopy Laboratory, Pacific Northwest National Laboratory, 3335 Innovation Blvd. Richland, WA 99354 Search for other works by this author on: Oxford Academic Google Scholar Libor Kovarik Libor Kovarik Environmental Molecular Spectroscopy Laboratory, Pacific Northwest National Laboratory, 3335 Innovation Blvd. Richland, WA 99354 Search for other works by this author on: Oxford Academic Google Scholar Microscopy and Microanalysis, Volume 21, Issue S3, 1 August 2015, Pages 425–426, https://doi.org/10.1017/S1431927615002925 Published: 23 September 2015
Limitations on the control of Schrödinger equations (2006)

We give the definitions of exact and approximate controllability for linear and nonlinear Schrödinger equations, review fundamental criteria for controllability and revisit a classical “No-go” result for evolution equations due to Ball, Marsden and Slemrod. In Section 2 we prove corresponding results on non-controllability for the linear Schrödinger equation and distributed additive control, and we show that the Hartree equation of quantum chemistry with bilinear control is not controllable in finite or infinite time. Finally, in Section 3, we give criteria for additive controllability of linear Schrödinger equations, and we give a distributed additive controllability result for the nonlinear Schrödinger equation if the data are small.
Systematic Literature Review of Security Pattern Research (2021)

Security patterns encompass security-related issues in secure software system development and operations that often appear in certain contexts. Since the late 1990s, about 500 security patterns have been proposed. Although the technical components are well investigated, the direction, overall picture, and barriers to implementation are not. Here, a systematic literature review of 240 papers is used to devise a taxonomy for security pattern research. Our taxonomy and the survey results should improve communications among practitioners and researchers, standardize the terminology, and increase the effectiveness of security patterns.
Automatic Inspection of Aeronautical Mechanical Assemblies by Matching the 3D CAD Model and Real 2D Images (2019)

In the aviation industry, automated inspection is essential for ensuring quality of production. It allows acceleration of procedures for quality control of parts or mechanical assemblies. As a result, the demand of intelligent visual inspection systems aimed at ensuring high quality in production lines is increasing. In this work, we address a very common problem in quality control. The problem is verification of presence of the correct part and verification of its position. We address the problem in two parts: first, automatic selection of informative viewpoints before the inspection process is started (offline preparation of the inspection) and, second, automatic treatment of the acquired images from said viewpoints by matching them with information in 3D CAD models is launched. We apply this inspection system for detecting defects on aeronautical mechanical assemblies with the aim of checking whether all the subparts are present and correctly mounted. The system can be used during manufacturing or maintenance operations. The accuracy of the system is evaluated on two kinds of platform. One is an autonomous navigation robot, and the other one is a handheld tablet. The experimental results show that our proposed approach is accurate and promising for industrial applications with possibility for real-time inspection.
Long-Term Outcome in Children with Fractures of the Proximal Femur after High-Energy Trauma (1999)

We found favorable long-term outcome in type II to type IV fractures. In these patients, restrictions of function were usually caused by other associated injuries. All patients with type I fractures presented with poor outcome secondary to their proximal femoral fractures, and not because of other associated injuries. Type I fractures during childhood and adolescence represent an unsolved problem.
Synthesis and Preliminary Complexation Studies of Dialkylphosphorylthiourea and Guanidines (1994)

Abstract Organic compounds containing a 1-phosphoryl-2-aza-3-thiocarbonyl group (IIa) or a 1-phosphoryl-3-imino group (IIb-g) were prepared by a two phases reaction between dialkylphosphite and thiourea or the appropriate guanidine. The complexation studies carried out by UV titration method and conductivity measurements showed that these ligands complex metal ions like Cu2+, Co2+, Cd2+, Hg2+, Pb2+, Fe3+, Zn2+, Ni2+ and Al3+ in neutral solution.
Breaking the Vendor Lock (2022)

High performance computing (HPC) systems pervasively feature GPU accelerators. For maximum efficiency, these are usually programmed using vendor-specific languages, such as CUDA. However, this is not portable and leads to vendor lock-in. Existing portable proramming models require transcribing the whole application, which is tedious and often results in sub-optimal performance without necessarily avoiding the need to maintain multiple versions. Although solutions for automated translation exist, they sacrifice either features of the original model, performance, or both.
3D integration of sub-surface photonics with CMOS (2006)

The integration of photonics and electronics on a single silicon substrate requires technologies that can add optical functionalities without significantly sacrificing valuable wafer area. To this end, we have developed an innovative fabrication process, called SIMOX 3-D Sculpting, that enables monolithic optoelectronic integration in a manner that does not compromise the economics of CMOS manufacturing. In this technique, photonic devices are realized in subsurface silicon layers that are separated from the surface silicon layer by an intervening SiO<sub>2</sub> layer. The surface silicon layer may then be utilized for electronic circuitry. SIMOX 3-D sculpting involves (1) the implantation of oxygen ions into a patterned silicon substrate followed by (2) high temperature anneal to create buried waveguide-based photonic devices. This process has produced subterranean microresonators with unloaded quality factors of 8000 and extinction ratios >20dB. On the surface silicon layers, MOS transistor structures have been fabricated. The small cross-sectional area of the waveguides lends itself to the realization of nonlinear optical devices. We have previously demonstrated spectral broadening and continuum generation in silicon waveguides utilizing Kerr optical nonlinearity. This may be combined with microresonator filters for on-chip supercontiuum generation and spectral carving. The monolithic integration of CMOS circuits and optical modulators with such multi-wavelength sources represent an exciting avenue for silicon photonics.
Programmable input/output interface circuit with five operation modes (2010)

This paper presents a programmable input/output interface circuit for some types of field programmable gate array (FPGA) devices which may be used in relatively high voltage (e.g. 5.5V) environments. The proposed circuit provides five different operation modes so that these FPGA devices are capable of connecting with multiple types of IC devices, including high voltage devices and PCI devices. In the proposed circuit, various circuit techniques are used to eliminate gate-oxide overstress and Pad to output supply (Vcco) leakage current when these FPGA devices connect with high voltage devices, and to ensure that over-voltage and under-voltage at Pad is avoidable when these FPGA devices connect with PCI devices. The proposed circuit can be used as an interface IP and had been successfully applied in a 200MHz SRAM-based FPGA device using both 2.5V and 3.3V MOS transistors in a 0.25um CMOS process with dual-oxide option.
Improvement of bow-tie antennas for pulse radiation (2003)

In some applications, such as impulse ground penetrating radar (GPR), one frequently needs a transmit waveform with minimal late-time ringing caused by multiple reflections at the antenna open ends. We propose a novel method in which late-time ringing can be significantly reduced while keeping radiation efficiency high. End reflections are reduced by extending the length of the antenna using an array of conducting strips so as to form an array of narrow slots in front of the open ends. The energy reflected at the open ends is therefore reduced and partly induced on the strips. The method has been implemented on a circular-end bow-tie antenna and experimentally verified using a monocycle with duration of 0.8 ns as input pulse. It has been observed that the transmit waveform has the shape of the time derivative of the input pulse with a very flat tail. The slots/strips profile can be optimized to obtain minimal late-time ringing, and the feed point to first slot distance can be optimized to obtain maximal pulse amplitude which can be as high as nearly twice the amplitude of a conventional bow-tie antenna.
Simultaneous Removal of Carbon and Nitrogen from Swine Wastewater Using an Immobilized-Cell Reactor (2006)

A single-stage phosphorylated polyvinyl alcohol immobilized-cell reactor with three operation modes was employed to investigate the efficiency of simultaneous carbon/nitrogen removal from raw swine wastewater. In continuous aeration mode, the removal efficiency of chemical oxygen demand (COD) and total nitrogen (T-N) exceeded 70 and 8%, respectively, at hydraulic retention time of 10days. In intermittent aeration (IA) mode, the removal efficiency of COD and T-N was more than 85 and 46%, respectively, when the reactor was set at 50% aeration duration to cycle time to operate at three aerobic-anoxic cycles per day. When oxidation-reduction-potential control was adopted to control the duration of the anoxic period in the real-time controlled (RTC) IA mode for a 4h aeration period, the total cycle time was reduced by about 20% with a slight increase in removal efficiency of COD (87%) and T-N (47%). The system with no extra chambers required is efficient in simultaneous carbon/nitrogen removal.
Properties of Short Fiber Reinforced Cement Paste for Concrete Tubes Produced by a Centrifugation Method (2004)

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