gebhart/patrepeval huggingface dataset:
Indices of polarimetric purity: application in biological tissues (2021)

Complete characterization of biological samples is of potential interest in different industrial and research areas, as for instance, in biomedical applications, for the recognition of organic structures or for the early detection of some diseases. During the last decades, polarimetric methods are experiencing an increase of attention in the study of biomedical tissues, and they are nowadays used in such framework to provide qualitative (polarimetric imaging) and quantitative (data processing) information for the studied samples. Polarimetric methods are based on the analysis of polarization modifications produced by light-matter interactions which can be triggered by a number of complex internal processes but can be roughly understood as the result of the combination of three pure polarimetric features of the sample: its diattenuation, retardance and depolarization. For the analysis of the depolarization content, we propose the use of the Indices of Polarimetric Purity (IPP) to describe the sample behavior. Related with the randomness of the scattering processes, IPPs provide more information of depolarizing systems than the widely used depolarization index (p&utri;), which further synthetize the depolarization content of samples. Moreover, certain combinations of IPP parameters leads to p&utri;. As a result, IPPs allow the revelation of some structures from tissue samples hidden in regular intensity images of even in the p&utri; channel, leading to better tissue classification results. In this work, we present different applications of IPPs in biomedical tissue that show its potential, which are not restricted to the biomedical framework as relevant results in plants characterization are also presented.
Estimating a Mean-Path from a set of 2-D curves (2015)

To perform many common industrial robotic tasks, e.g. deburring a work-piece, in small and medium size companies where a model of the work-piece may not be available, building a geometrical model of how to perform the task from a data set of human demonstrations is highly demanded. In many cases, however, the human demonstrations may be sub-optimal and noisy solutions to the problem of performing a task. For example, an expert may not completely remove the burrs that result in deburring residuals on the work-piece. Hence, we present an iterative algorithm to estimate a noise-free geometrical model of a work-piece from a given dataset of profiles with deburring residuals. In a case study, we compare the profiles obtained with the proposed method, nonlinear principal component analysis and Gaussian mixture model/Gaussian mixture regression. The comparison illustrates the effectiveness of the proposed method, in terms of accuracy, to compute a noise-free profile model of a task.
Investigation of biological activities of two cultivars of Cicer arietinum proteins mass associated with A lzheimer's disease (2023)

Alzheimer's disease (AD) is the most common cause of dementia in the elderly, with some known classical factors. Cicer arietinum (Leguminosae) is a source of protein for humans and contains albumin, globulin, glutelin, and prolamin. The protein content of two cultivars of C. arietinum, Hashem and Mansour, was isolated to evaluate their inhibition activity against acetylcholinesterase (AChE), butyrylcholine esterase (BChE), and β-amyloid peptide (βA) aggregation. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and molecular docking were also applied to evaluate the content and determine the potential of each chickpea protein to interact with AChE, respectively. Obtained data showed that proteins from both cultivars could inhibit AChE with IC50 of 17.73 (0.03) and 22.20 (0.06) μg/mL, respectively, with no activity on BChE. The 50 μg/mL protein concentration of each cultivar suppressed βA accumulation (Mansour: 25.66% and Hashem: 21.69%) and showed biometal chelating activity. SDS-PAGE analysis revealed relatively different protein patterns, though the Mansour cultivar contained some protein bands with molecular weights of 18, 24, and 70 kDa were estimated to belong to vicilin and legumin, which were absent in the Hashem protein mass. Molecular docking showed that legumin and especially vicilin have good potential to interact with AChE. The chickpea proteins showed inhibitory activity against AChE, which might be due to the vicilin and legumin fractions. The characterization of the inhibitory effect of each protein band could be promising in finding new therapeutic peptide candidates to treat Alzheimer's in the future, although more experimental work is needed in this issue.
Somatic Hypermutation and Class Switch Recombination in Msh6−/−Ung−/− Double-Knockout Mice (2006)

Somatic hypermutation (SHM) and class switch recombination (CSR) are initiated by activation-induced cytosine deaminase (AID). The uracil, and potentially neighboring bases, are processed by error-prone base excision repair and mismatch repair. Deficiencies in Ung, Msh2, or Msh6 affect SHM and CSR. To determine whether Msh2/Msh6 complexes which recognize single-base mismatches and loops were the only mismatch-recognition complexes required for SHM and CSR, we analyzed these processes in Msh6(-/-)Ung(-/-) mice. SHM and CSR were affected in the same degree and fashion as in Msh2(-/-)Ung(-/-) mice; mutations were mostly C,G transitions and CSR was greatly reduced, making Msh2/Msh3 contributions unlikely. Inactivating Ung alone reduced mutations from A and T, suggesting that, depending on the DNA sequence, varying proportions of A,T mutations arise by error-prone long-patch base excision repair. Further, in Msh6(-/-)Ung(-/-) mice the 5' end and the 3' region of Ig genes was spared from mutations as in wild-type mice, confirming that AID does not act in these regions. Finally, because in the absence of both Ung and Msh6, transition mutations from C and G likely are "footprints" of AID, the data show that the activity of AID is restricted drastically in vivo compared with AID in cell-free assays.
Multicenter Study of General Anesthesia. I. Design and Patient Demography (1990)

A prospective randomized clinical trial of enflurane, fentanyl, halothane, and isoflurane is described. The 17,201 patients were stratified into two groups (preanesthetic medication and no preanesthetic medication) and were randomized to one of four study agents: enflurane, fentanyl, halothane, and isoflurane. Fifteen university-affiliated hospitals in the United States and Canada participated. All patients were first assessed preoperatively. Data were collected during anesthesia, in the immediate recovery period, and for up to 7 days after anesthesia/surgery. The mean age of the patients was 43 yr, the mean height 167 cm, and the mean weight 68 kg. Sixty-five percent of patients were female. In this study 90.7% of patients were classified as ASA Physical Status 1 or 2, and 34.7% of patients smoked. It is concluded that pooling of data across institutions was valid and does allow determination of the efficacy and relative safety of the four study agents.
Characteristics of high-efficiency InGaN-based white LED lighting (2000)

The basic illumination characteristics of an efficient white LEDs lighting source, which is composed of cannon-ball type 10 cd-class InGaN-based white LEDs, are described. It is noted that the temperature and forward-bias current dependence under full wave rectification of AC 100 V gives a significant effect to both electroluminescence properties and luminous efficacy. We have obtained a maximum luminous intensity of 95000 cd/m<SUP>2</SUP> and a luminous efficacy of about 27 lm/W at an electric power of 20 W (at a constant current of 10 mA). The developed white LEDs lighting source indicates two injection electroluminescence peaks at 465 and 555 nm, which are originated from a blue LED and a YAG:Ce<SUP>3+</SUP> phosphor, respectively. The illuminance distribution of the LED lighting source was analyzed using our `multi sources of LED light' theory. We have performed the design of a street lighting as the practical application using the 700 LEDs array lighting source.
Adaptive Input-Power Distribution in Doherty Power Amplifiers for Linearity and Efficiency Enhancement (2010)

A new technique based on an adaptive input-power distribution is introduced to overcome the limitations of practical Doherty power amplifiers. The proposed Doherty amplifier employs an extended-resonance power-divider at its input. By taking advantage of the auxiliary cell's nonlinear input impedance, the extended-resonance divider is designed such that it provides a proper power-dependent power-division between the main and auxiliary cells. Therefore, the two cells are efficiently driven and can generate output current and voltage characteristics similar to the ideal Doherty amplifier, resulting in both linearity and efficiency improvements. The performance of the new Doherty amplifier is compared with a conventional design through simulations and measurements. The proposed Doherty amplifier achieves a measured ACLR improvement of 5-7 dB over a wide range of output power levels, as well as an increased power-added-efficiency of up to 5% for WCDMA signals. The proposed Doherty design does not require complex circuitry and yields a compact circuit.
Nonlinear Response of Laminated Cylindrical Shell Panels Subjected to Thermomechanical Loads (2006)

The nonlinear response of multi-layered composite cylindrical shell panels subjected to thermomechanical loads are studied in this article. The structural model is based on the first order shear deformation theory incorporating geometric nonlinearities. The nonlinear equilibrium paths are traced using the arc-length control algorithm within the framework of finite element method. Hashin’s failure criterion has been adopted to predict the first-ply failure of cylindrical laminates. Both temperature independent and temperature dependent elastic properties are considered in the analysis. Specific numerical results are reported to show the effect of radius-to-span ratio, thickness-to-span ratio, laminate stacking sequence, and boundary condition on stability characteristics of laminated cylindrical shell panels subjected to combined thermal and mechanical transverse loads.
Repair of anomalous origin of the left coronary artery from the pulmonary artery without early and late mortality in 9 patients. (1992)

An anomalous origin of the left coronary artery from the pulmonary artery is a very rare congenital malformation. We examined the early and late results of 9 patients (4 males and 5 females, mean age at operation: 6.5 years +/- 6 years). Eleven operations were performed in these 9 patients. The following types of operation were performed: ligation of the left coronary artery close to the pulmonary artery in one case, coronary artery bypass grafting in 3 patients, reimplantation of the LCA into the aorta in 3 patients and interpulmonary artery tunnel repair ("tunnel operation") in 4 instances. These operations were combined with plastic reconstruction of the mitral valve (1 patient) or aneurysmectomy of the left ventricle (3 patients). There was no intra- or early operative mortality. After a mean follow-up of 7.3 years, all patients are alive and in New York Heart Association functional class I, except one patient suffering from dyspnoea during moderate exercise. In two patients complications requiring reoperations occurred after 4 and 100 months respectively: stenosis of the distal anastomosis after coronary artery bypass grafting using saphenous vein and thrombosis of the intrapulmonary tunnel. We conclude that an anomalous origin of the left coronary artery from the pulmonary artery is best operated by reimplantation of the vessel into the aorta at any age of life. Concomitant pathology may be corrected simultaneously, without increasing operative mortality.
gun Sezimi Detecting Driver Drowsiness Using Computer Vision Techniques (2008)

The advance of computing technology has provided the means for building intelligent vehicle systems. Drowsy driver detection system is one of the potential applications of intelli- gent vehicle systems. Here we employ machine learning tech- niques to detect driver drowsiness. The system obtained 98% performance in predicting driver drowsiness. This is the high- est prediction rate reported to date for detecting real drowsiness. Moreover, the analysis revealed new information about human behavior during drowsy driving.
Sindrome da ipotensione liquorale secondaria a rachicentesi in un paziente con AIDS linfoma non Hodgkin (1998)

Viene descritto il caso di un paziente affetto da AIDS e Linfoma non Hodgkin con sindrome da ipotensione liquorale secondaria a ripetute punture lombari. La TC e la RM mostravano una duplice raccolta sottodurale a contenuto liquorale, con impregnazione della pachimeninge, associata ad effetto compressivo sull'encefalo e dislocazione verso il basso del tronco encefalico. Il quadro clinico si risolveva spontaneamente in circa due settimane, così come confermato dai reperti neuroradiologici.
Novel Chemokine-Based Immunotoxins for Potent and Selective Targeting of Cytomegalovirus Infected Cells (2017)

Immunotoxins as antiviral therapeutics are largely unexplored but have promising prospective due to their high selectivity potential and their unparalleled efficiency. One recent example targeted the virus-encoded G protein-coupled receptor US28 as a strategy for specific and efficient treatment of human cytomegalovirus (HCMV) infections. US28 is expressed on virus-infected cells and scavenge chemokines by rapid internalization. The chemokine-based fusion-toxin protein (FTP) consisted of a variant (F49A) of CX<sub>3</sub>CL1 specifically targeting US28 linked to the catalytic domain of <i>Pseudomonas exotoxin</i> A (PE). Here, we systematically seek to improve F49A-FTP by modifications in its three structural domains; we generated variants with (1) altered chemokine sequence (K14A, F49L, and F49E), (2) shortened and elongated linker region, and (3) modified toxin domain. Only F49L-FTP displayed higher selectivity in its binding to US28 versus CX<sub>3</sub>CR1, the endogenous receptor for CX<sub>3</sub>CL1, but this was not matched by a more selective killing of US28-expressing cells. A longer linker and different toxin variants decreased US28 affinity and selective killing. Thereby, F49A-FTP represents the best candidate for HCMV treatment. Many viruses encode internalizing receptors suggesting that not only HCMV but also, for instance, Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus may be targeted by FTPs.
Channel-adaptive video streaming using packet path diversity and rate-distortion optimized reference picture selection (2004)

In this paper, we present error-resilient Internet video transmission using path diversity and rate-distortion optimized reference picture selection. Under this scheme, the optimal packet dependency is determined adapting to channel characteristics and video content, to achieve a better trade-off between coding efficiency and forming independent streams to increase error resilience. Packets are sent over the selected path that minimizes the distortion, while taking advantage of path diversity. Experiments demonstrate that the proposed scheme provides significant gains over video redundancy coding and the NACK mode of conventional reference picture selection.
From 3D scene geometry to human workspace (2011)

We present a human-centric paradigm for scene understanding. Our approach goes beyond estimating 3D scene geometry and predicts the "workspace" of a human which is represented by a data-driven vocabulary of human interactions. Our method builds upon the recent work in indoor scene understanding and the availability of motion capture data to create a joint space of human poses and scene geometry by modeling the physical interactions between the two. This joint space can then be used to predict potential human poses and joint locations from a single image. In a way, this work revisits the principle of Gibsonian affordances, reinterpreting it for the modern, data-driven era.
Heat Transfer in Chemical Vapor Deposited Optical Fiber Coatings (2001)

Abstract A fundamental understanding of how reactor parameters influence the fiber surface temperature is essential to manufacturing high quality optical fiber coatings by chemical vapor deposition (CVD). In an attempt to better understand this process, a finite volume model has been developed to study the gas flow and heat transfer of an optical fiber as it travels through a CVD reactor. This study showed that draw speed significantly affects fiber temperature inside the reactor, with temperature changes up to 45% observed under the conditions studied. Multiple heat transfer modes contribute to this phenomena, with convection heat transfer dominating the process.
LATE FISTULIZATION OF OPERATIVE WOUNDS (1950)

AMONG the postoperative complications of intraocular surgery, those of late fistula formation and hypotony have received relatively little attention. We desire to emphasize a type of slowly leaking cicatrix, to describe the associated symptom complex and to present a method of therapy which we have found successful. Owing to imperfect closure, any penetrating wound of an eyeball, either traumatic or surgical, may be followed by a cystoid scar. The creation of such a cicatrix is in some instances the aim of the surgeon, while in others the condition occurs when least desired. If such a cicatrix opens to the surface, a fistula is produced. This fistulous tract may be large or small. It may be constantly open, or it may be closed at times and open at others. The clinical appearance of the usual form, in which the fistula is large and open at all times, is well known. The
II Propositional Dynamic Logic (2000)

Among the many approaches to formal reasoning about programs, Dynamic Logic enjoys the singular advantage of being strongly related to classical logic. Its variants constitute natural generalizations and extensions of classical formalisms. For example, Propositional Dynamic Logic (PDL) can be described as a blend of three complementary classical ingredients: propositional calculus, modal logic, and the algebra of regular events. In First-Order Dynamic Logic (DL), the propositional calculus is replaced by classical first-order predicate calculus. Dynamic Logic is a system of remarkable unity that is theoretically rich as well as of practical value. It can be used for formalizing correctness specifications and proving rigorously that those specifications are met by a particular program. Other uses include determining the equivalence of programs, comparing the expressive power of various programming constructs, and synthesizing programs from specifications.This book provides the first comprehensive introduction to Dynamic Logic. It is divided into three parts. The first part reviews the appropriate fundamental concepts of logic and computability theory and can stand alone as an introduction to these topics. The second part discusses PDL and its variants, and the third part discusses DL and its variants. Examples are provided throughout, and exercises and a short historical section are included at the end of each chapter.
Inhibition of Dicing of Guanosine‐Rich shRNAs by Quadruplex‐Binding Compounds (2008)

RNA interference is triggered by small hairpin precursors that are processed by the endonuclease dicer to yield active species such as siRNAs and miRNAs. To regulate the RNAi-mediated suppression of gene expression, we imagined a strategy that relies on the sequence-specific inhibition of shRNA precursor processing by immediate RNA-small molecule interactions. Here, we present a first step in this direction by augmenting shRNAs with guanosine-rich sequences that are prone to fold into four-stranded structures. The addition of small molecules that selectively bind to such quadruplex sequences should allow for the specific inhibition of dicing of shRNAs that contain suitable G-rich elements. In an attempt to find compounds that protect against dicer processing, we have examined the effects of quadruplex-binding compounds on the dicer processing of shRNAs containing G-quadruplexes. Although a variety of small molecules that are known to bind to quadruplexes inhibited in vitro dicing of shRNAs, only two substance classes, namely certain porphyrazines and bisquinolinium compounds, showed selective inhibition of G-rich shRNAs compared to control sequences lacking guanine-rich elements. The G-rich shRNAs displayed a potent knockdown of gene expression in mammalian cell culture, but the effect was not influenced by addition of the respective quadruplex-binding compounds.
Failure mechanism analysis of quartz accelerometer under vibration condition (2011)

Accelerometer is a sensor which converts acceleration that acts on the transport input shaft to an electrical signal by a variety of means of measurements. Acceleration will change into velocity by integration, while acquire the position information by the second integration. Through measuring linear acceleration of vehicle along the certain direction by accelerometer, inertial navigation system can determine the instantaneous velocity and position of transporter relative to the reference coordinate system by necessary integration and coordinate transformation. As one of the most critical parts of platform inertial navigation system, accelerometer performance directly affects the measurement accuracy, stability of the system, and the ultimate navigation accuracy. Accelerometer is mainly affected by vibration stress during transport process. Vibration will make accelerometer's structure distort, resulting in drift of bias value and scale factor. The flexible bridge of accelerometer may break down because of the stress concentration in the instantaneous impact. Finite element analysis software ANSYS will be used for quartz accelerometer to model and simulate. Analysis of random vibration or shock vibration indicates that the quartz accelerometer can withstand the instantaneous impact for the provision of accelerometer magnitude of 180g. Meanwhile, single point response spectrum analysis under the transport vibration comes to a conclusion that accelerometer's structure will distort under the transport vibration, leading to the change of pendulum performance and torque coefficient, at last resulting in the parameter drift. The parameter drift is often caused by the releasing process of structure residual stress. The failure of accelerometer resulting from the parameter drift could be avoided by the method of stabilization of material and acceleration stabilization of the accelerometer.
Designing Full-Connectivity WDM Optical Interconnects with Reduced Switching and Conversion Complexity (2006)

Most existing wavelength division multiplexing (WDM) optical interconnects make use of a large number of switching elements and require wide-range tunable wavelength converters to support full-connectivity among inputs and outputs. This results in complex and expensive designs. In this paper, we propose new full-connectivity single-stage and multi-stage WDM optical interconnects with and reduced hardware complexity. The proposed designs require a smaller number of switching elements and use only fixed-range wavelength conversion. Analysis of hardware complexity shows that, the proposed designs have a smaller number of switching and conversion costs compared to most existing interconnects