gebhart/patrepeval huggingface dataset:
Adaptive Control of Variable Speed Wind Turbines (2001)

This paper discusses the development of an adaptive feedback linearisation controller for a variable speed wind turbine. The controller provides an adaptive estimate of the turbine shaft torque. A feedback linearisation controller utilises the torque estimate to provide a torque reference for a field oriented squirrel cage induction machine. The induction machine is connected through a gearbox to the turbine shaft. The feedback linearisation controller ensures that a linear relationship is maintained between the turbine speed and an additional user defined input. The additional input is designed using linear control theory to provide stable error dynamics and speed tracking. The speed reference for the controller is a function of the wind speed and is chosen to ensure maximum energy capture from the wind for varying wind conditions. Simulation results demonstrate the effectiveness of such a controller in capturing maximum available energy from the wind. Resume - Cet article presente le developpement d'un controleur adaptatif, feedback linearisation, d'une turbine a vitesse variable d'une Eolienne. Le controleur permet une estimation adaptative de l'axe du moment d'inertie. Il utilise la valeur du moment de torsion estime pour definir un moment de torsion de reference pour le champ oriente cage ecureuil d'une machine a induction. La machine a induction est connectee a l'axe de la turbine a travers la boite a vitesse. Le controleur assure une relation lineaire entre la vitesse de la turbine et un utilisateur additionnel defini a l'entree. L'entree additionnel est choisie en utilisant la theorie du controle lineaire pour donner une erreur dynamique stable et assure le suivi de la trajectoire de la vitesse. La vitesse de reference pour le controleur est une fonction de la vitesse du vent et elle est choisie pour assurer un maximum d'energie fournie par le vent dans des conditions variables. Les resultats de la simulation demontrent l'efficacite d'un tel controleur pour l'enregistrement du maximum d'energie disponible.
Les violences sexuelles dans l'enfance chez les femmes kanakes de Nouvelle-Calédonie : vers un abaissement du seuil des violences tolérées (2010)

<titre>Résumé</titre>Este artículo se interesa en el abuso sexual de la infancia entre las mujeres kanakas en Nueva Caledonia (Pacífico). Los datos proceden de una estudio sobre mujeres entre 18-54 años de edad. Entre las mujeres Kanakas, una cada ocho informo de haber si do victima de abuso sexual antes de los 15 años. La mayoría de los casos fueron perpetrados por un miembro varón de la familia. Las mujeres jóvenes tenían más probabilidades de abuso sexual en la niñez que la mayores. Los resultados conducen a examinar las cuestiones planteadas por la medición de abuso sexual en la niñez en esa comunidad indígena, en la cual la persistencia de las desigualdades sociales relacionadas con la historia colonial coexisten con una rápida transformacion social en materia de género y en las familias.
Augmented expression of endothelin‐1, endothelin‐3 and the endothelin‐B receptor in breast carcinoma (2000)

These results suggest that the ET system is altered in breast carcinomas and this may be of importance in the progression from in-situ to invasive carcinoma.
1H and 13C NMR spectra of fifteen substituted isoquinolines (1991)

Abstract Detailed analyses of the 1 H and 13 C NMR spectra of fifteen mono‐ and di‐substituted isoquinoline derivatives were carried out by two‐dimensional 1 H– 1 H and 1 H– 13 C shift correlation and nuclear Overhauser effect difference techniques.
Date Pit-Based Additive as Density Reducing Agent in Underbalanced Drilling (2018)

Abstract A new drilling fluid additive has been developed for application as density reducing agent. The additive can be used for preparing lightweight drilling fluid formulation for use in underbalanced drilling. The preliminary results obtained from the performance analysis revealed that the date pit - based additive possesses some potential to be used as a density and formation fluid flow control agents in water-based drilling fluid. The addition of 5ml (ca 1.40 vol%) of the additive to bentonite drilling fluid formation decreased the density of the fluid by 21%. The effect of the additive on other drilling fluid properties such as fluid loss and filter cake thickness were also evaluated.
Evolution of flowers and inflorescences (1994)

ABSTRACT Plant development depends on the activity of meristems which continually reiterate a common plan. Permutations around this plan can give rise to a wide range of morphologies. To understand the mechanisms underlying this variation, the effects of parallel mutations in key developmental genes are being studied in different species. In Antirrhinum, three of these key genes are: (1) floricaula (flo) a gene required for the production of flowers (2) centrora- dialis (cen), a gene controlling flower position (3) cycloidea (eye), a gene controlling flower symmetry. Several plant species, exhibiting a range of inflorescence types and floral symmetries are being analysed in detail. Comparative genetic and molecular analysis shows that inflorescence architecture depends on two underlying parameters: a basic inflorescence branching pattern and the positioning of flowers. The flo and cen genes play a key role in the positioning of flowers, and variation in the site and timing of expression of these genes, may account for many of the different inflorescence types. The evolution of inflorescence structure may also have influenced the evolution of floral asymmetry, as illustrated by the cen mutation which changes both inflorescence type and the symmetry of some flowers. Conflicting theories about the origins of irregular flowers and how they have coevolved with inflorescence architecture can be directly assessed by examining the role of eye- and cen-like genes in species displaying various floral symmetries and inflorescence types.
The Burns Registry of Australia and New Zealand: progressing the evidence base for burn care (2016)

Despite the highly centralised delivery of care to patients with severe or complex burn injury, and the relatively small number of specialist burn units, we found significant variation between units in clinical management and in outcomes. BRANZ data from its first 4 years of operation support its feasibility and the value of further development of the registry. Based on these results, the focus of ongoing research is to improve understanding of the reasons for variations in practice and of their effect on outcomes for patients, and to develop evidence-informed clinical guidelines for burn management in Australia and New Zealand.
Bone cutting (1991)

Bone cutting has always been a problem for surgeons because bone is a hard living material, and many osteotomes are still very crude tools. Technical improvement of these surgical tools has first been their motorization. Studies of the bone cutting process have indicated better features for conventional tools. Several non-conventional osteotomes, particularly ultrasonic osteotomes are described. Some studies on the possible use of lasers for bone cutting are also reported. Use of a pressurised water jet is also briefly examined. Despite their advantages, non-conventional tools still require improvement if they are to be used by surgeons.
Pembrolizumab as Neoadjuvant Therapy Before Radical Cystectomy in Patients With Muscle-Invasive Urothelial Bladder Carcinoma (PURE-01): An Open-Label, Single-Arm, Phase II Study (2018)

Neoadjuvant pembrolizumab resulted in 42% of patients with pT0 and was safely administered in patients with MIBC. This study indicates that pembrolizumab could be a worthwhile neoadjuvant therapy for the treatment of MIBC when limited to patients with PD-L1-positive or high-TMB tumors.
Identification of Novel ERK2 Substrates through Use of an Engineered Kinase and ATP Analogs (2003)

The mitogen-activated protein kinases are key regulators of cellular organization and function. To understand the mechanisms(s) by which these ubiquitous kinases affect specific cellular changes, it is necessary to identify their diverse and numerous substrates in different cell contexts and compartments. As a first step in achieving this goal, we engineered a mutant ERK2 in which a bulky amino acid residue in the ATP binding site (glutamine 103) is changed to glycine, allowing this mutant to utilize an analog of ATP (cyclopentyl ATP) that cannot be used by wild-type ERK2 or other cellular kinases. The mutation did not inhibit ERK2 kinase activity or substrate specificity in vitro or in vivo. This method allowed us to detect only ERK2-specific phosphorylations within a mixture of proteins. Using this ERK2 mutant/analog pair to phosphorylate ERK2-associated proteins in COS-1 cells, we identified the ubiquitin ligase EDD (E3 identified by differential display) and the nucleoporin Tpr (translocated promoter region) as two novel substrates of ERK2, in addition to the known ERK2 substrate Rsk1. To further validate the method, we present data that confirm that ERK2 phosphorylates EDD in vitro and in vivo. These results not only identify two novel ERK2 substrates but also provide a framework for the future identification of numerous cellular targets of this important signaling cascade.
Microwave Absorption by Normal and Tumor Cells (1971)

Energy levels exist in mammalian cells which result in the absorption of microwaves between 66 and 76 gigahertz. Many of these energy levels occur when water molecules associate with the various chemical groups of macromolecules. The absorption spectra of cells between 66 and 76 gigahertz, therefore, is determined by the structure of in vivo water lattices, and these seem to reflect indirectly the structural makeup of macromolecules or macromolecular complexes. Tumor cells absorb 66-, 68-, and 70-gigahertz microwaves less strongly and 69-, 72-, and 75-gigahertz microwaves more strongly than normal cells. These differences in the strength of attenuation at each frequency suggest that either the ratio of RNA to DNA or the relative number of certain types of chemical groups in tumor cells is different from that in normal cells.
Everolimus (E) plus bevacizumab (B) is effective first-line treatment for patients (pts) with advanced renal cell carcinoma (RCC) with papillary features (PF): Results from a phase II trial. (2018)

627 Background: We previously reported on a phase II trial of E+B across various non-clear cell RCC histologies and observed significant activity among pts with papillary or unclassified RCC ( uRCC ) with PF (objective response rate [ORR] 39%, median progression-free survival [PFS] 12.9 months [m]; Voss, JCO, 2016). An expansion cohort limited to these two histologies was conducted to confirm the efficacy of E+B. Methods: E + B was administered at standard doses until progressive disease (PD) or intolerance to therapy. The current analysis included 19 pts with pRCC or uRCC with PF in the initial cohort and 20 pts in the expansion cohort (total n=39). The primary endpoint was 6 month PFS with secondary endpoints of ORR, median PFS, and overall survival (OS). Correlative analyses included next generation sequencing (NGS) from tumor and germline across &gt;341 genes of interest. Results: Of 39 pts, 24 had uRCC with PF, 14 had papillary RCC, and 1 had translocation RCC with PF. Among 37 evaluable pts, the ORR was 35%; 43% for uRCC with PF and 23% for papillary RCC. Six-month PFS for all 39 pts was 78%; 82% for uRCC with PF and 68% for papillary RCC. Median PFS was 13.7m; 13.7m for uRCC with PF and 8.4m for papillary RCC (Table). With median followup of 17.6m, median OS is 33.9m. Toxicity with E+B was similar to previous reports. 33 of 39 pts had NGS performed and partial responses were observed across a wide spectrum of genomic alterations, including several recurrently seen in papillary RCC variants such as mutations in FH, MET, NF2, and ARID1a. Conclusions: The expansion cohort confirms the activity of E+B for pts with advanced papillary RCC or uRCC with PF with superior ORR, PFS, and OS compared to historical results with sunitinib for these histologies. E+B represents a new standard first-line treatment option for these pts. Clinical trial information: NCT01399918. [Table: see text]
REPUTATION, INC.: THE INDUSTRIALIZATION OF DIGITAL SELF PRESENTATION AND ONLINE PRIVACY (2014)

As with the introduction of any new communication technology, the growth of the commercial web in the 1990s generated concerns about how the new medium might challenge normative and structural boundaries between private and public realms. In response to fears about the internet's potential to destabilize existing norms governing interpersonal interaction, a number of companies emerged beginning in the mid-1990s to help people manage their visibility online. This "commercial privacy industry" operates at the intersection of theories of self-presentation, identity, reputation, and privacy. The practices of the companies that make up this industry simultaneously reflect and influence the anxieties that shape evolving social norms around these important sociological constructs. By exploring the shared articulations of risk and reward that underpin this emergent industry, I explore the internal logics and discursive patterns behind this industrial system and examine the implications of commercial incentives for personal privacy and image management. Through interviews with key members of the privacy industry, comprehensive textual analysis of industry and mainstream press reports, and analysis of selected policy and legal documents, I examine the role this proto-industry has played in constructing and reconstructing many of the defining features of digital culture in response to changing social, technical, political, and economic realities. With the overarching goal of exploring and understanding this group's self-construction in relation to established marketers and publishers, my dissertation project (1) provides an historical perspective on the evolution of commercial approaches to online privacy and self-presentation; (2) understands how different organizational actors conceive of the online privacy industry and how they position themselves within the digital ecosystem; (3) explores how these actors construct collective understandings of individual identity and reputation as sources of risk and opportunity; and (4) discusses whether these approaches disrupt or extend existing power relationships in the online ecosystem.
Wireless network simulators relevance compared to a real testbed in outdoor and indoor environments (2010)

In this paper, we propose a comparative study between results generated by a real 802.11 testbed in different outdoor and indoor environments and 3 usual network simulators (NS2, QualNet and OPNET). The goal of this study is to evaluate the relevance of the low layers recently implemented in these simulators. The motivation of this paper is to provide a guide to researchers to choose and parameterize a simulator according to a selected context. The study shows that the simulation results can be rather close to the experimental results. However, they are very dependent on the tuning of the physical layer parameters and the selected propagation models.
Pharmacokinetic study of intralesional cisplatin for the treatment of hepatocellular carcinoma (2001)

The prolonged t-max and initial half-life noted with the intralesional injection of cisplatin/epinephrine/collagen gel are consistent with its proclaimed ability to retain cisplatin at the tumor and delay its release in systemic circulation. The kinetics of intralesional cisplatin injection also suggest local sequestration of the drug in the injected site. Parameters of intravenous cisplatin infusion in cirrhotic patients are similar to those of patients from the historic control group.
Advances in catalysis science and technology (1985)

This comprehensive collection of authoritative papers covers both the fundamental and applied aspects of catalysts. Topics range from synthesis and characterization, and theories and concepts, through structure activity correlation, deactivation and regeneration, process optimization and scale-up, and homogenous catalysis. The book highlights the contributions of modern theories and novel techniques to emerging areas of catalysis chemistry.
Nonlinear transport phenomena in a triangular quantum well (1991)

We have measured transport properties in an AlGaAs/AlxGa1−xAs, triangular quantum well whose energy spectrum has been varied by means of gate bias. We have observed several nonlinear effects in the lateral conductance arising at positive gate voltages as the increasing Fermi level is moved toward the lowering energy positions of the excited subbands in the quantum well. We interpret our results in terms of electron population of the excited subbands in which electrons possess low mobility. Finally, we find new features at high lateral voltages which are considered to be an evidence of previous predicted electrophonon resonance.
Application of Artificial Neural Networks to Predict the Selling Price in the Real Estate Valuation Process (2011)

An artificial neural networks (ANN) approach was applied to develop a mathematic model which predicts the sales price of residential properties. The study is based on evaluation of sales of homes in Casablanca, Morocco Kingdom. North of Africa. A feed forward network with one hidden layer was trained using original set of residential property valuation database. The ANN was obtained by 148 sets of input-output patterns applying back propagation algorithm. For the networks, the Levenberg-Marquardt learning algorithms, the hyperbolic tangent sigmoid transfer function and the linear transfer function were used. The best fitting training data set was obtained from an ANN architecture composed by five neurons in the hidden layer, which made possible to predict the sales price of homes. The model gave good predictions with high correlation coefficient (R2=0.952). Also, the validation of the data set simulations was in good agreement with the original data. It is suggested that the new ANN model could be used as a tool for the reliable prediction of selling price values.
Comparative Genomics of Saccharomyces cerevisiae Natural Isolates for Bioenergy Production (2014)

Lignocellulosic plant material is a viable source of biomass to produce alternative energy including ethanol and other biofuels. However, several factors—including toxic by products from biomass pretreatment and poor fermentation of xylose and other pentose sugars—currently limit the efficiency of microbial biofuel production. To begin to understand the genetic basis of desirable traits, we characterized three strains of Saccharomyces cerevisiae with robust growth in a pretreated lignocellulosic hydrolysate or tolerance to stress conditions relevant to industrial biofuel production, through genome and transcriptome sequencing analysis. All stress resistant strains were highly mosaic, suggesting that genetic admixture may contribute to novel allele combinations underlying these phenotypes. Strain-specific gene sets not found in the lab strain were functionally linked to the tolerances of particular strains. Furthermore,genes with signatures of evolutionary selection were enriched for functional categories important for stress resistance and included stress-responsive signaling factors. Comparison of the strains’ transcriptomic responses to heat and ethanol treatment—two stresses relevant to industrial bioethanol production—pointed to physiological processes that were related to particular stress resistance profiles. Many of the genotype-by-environment expression responses occurred at targets of transcription factors with signatures of positive selection, suggesting that these strains have undergone positive selection for stress tolerance. Our results generate new insights into potential mechanisms of tolerance to stresses relevant to biofuel production, including ethanol and heat, present a backdrop for further engineering, and provide glimpses into the natural variation of stress tolerance in wild yeast strains.
Improvement to CDF grounded lattice codes (2004)

Lattice codes have been evaluated in the watermarking literature based on their behavior in the presence of additive noise. In contrast with spread spectrum methods, the host image does not interfere with the watermark. Such evaluation is appropriate to simulate the effects of operations like compression, which are effectively noise-like for lattice codes. Lattice codes do not perform nearly as well when processing that fundamentally alters the characteristics of the host image is applied. One type of modification that is particularly detrimental to lattice codes involves changing the amplitude of the host. In a previous paper on the subject, we describe a modification to lattice codes that makes them invariant to a large class of amplitude modifications; those that are order preserving. However, we have shown that in its pure form the modification leads to problems with embedding distortion and noise immunity that are image dependent. In the current work we discuss an improved method for handling the aforementioned problem. Specifically, the set of quantization bins that is used for the lattice code is governed by a finite state machine. The finite state machine approach to quantization bin assignment requires side information in order for the quantizers to be recovered exactly. Our paper describes in detail two methods for recovery when such an approach is used.
Ligand-Substitution Reactions of the Tellurium Compound AS-101 in Physiological Aqueous and Alcoholic Solutions (2016)

Since its first crystallization, the aqueous structure of the tellurium-containing experimental drug AS-101 has never been studied. We show that, under the aqueous conditions in which it is administered, AS-101 is subjected to an immediate ligand-substitution reaction with water, yielding a stable hydrolyzed oxide anion product that is identified, for the first time, to be TeOCl<sub>3</sub><sup>-</sup>. Studying the structure of AS-101 in propylene glycol (PG), an alcoholic solvent often used for the topical and oral administration of AS-101, revealed the same phenomenon of ligand-substitution reaction between the alcoholic ligands. Upon exposure to water, the PG-substituted product is also hydrolyzed to the same tellurium(IV) oxide form, TeOCl<sub>3</sub><sup>-</sup>.
Polymerization of Trioxane Initiated by Isomeric 2,4,5-Trisubstituted 1,3-Dioxolan-2-ylium Salts (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPolymerization of Trioxane Initiated by Isomeric 2,4,5-Trisubstituted 1,3-Dioxolan-2-ylium SaltsZbigniew Jedlin'ski and Miroslaw GibasCite this: Macromolecules 1980, 13, 6, 1700–1703Publication Date (Print):November 1, 1980Publication History Published online1 May 2002Published inissue 1 November 1980https://pubs.acs.org/doi/10.1021/ma60078a061https://doi.org/10.1021/ma60078a061research-articleACS PublicationsRequest reuse permissionsArticle Views59Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts