gebhart/patrepeval huggingface dataset:
VAT-associated ST2+Tregs from omentum support tolerance to peripheral tumors (2017)

Abstract Tumor metastasis to theomentum is associated with poor clinical outcomes. Although the omentum hasimmune function due to the activities of milky spots, the role of this organ inanti-tumor immunity has not been completely described. By implanting tumor cells in mice we found that peritoneal tumors are not rejected and cause an increasein visceral adipose tissue (VAT)-associated regulatory T cells in the omentumas well as low frequency of tumor specific CD8 T cells. Additionally, peritoneal tumors impaired the immunity to secondary dermal tumors by limiting the expansion of tumor specific CD8 T cells that mediate tumor rejection. To better understand this phenomenon, we studied the VAT-associated Tregs, which can be divided in ST2+ and ST2- (ST2 a component of the IL-33R). Particularly, VAT-associated ST2+ Tregs are not found in conventional lymphoid organs, nonetheless we find that following peritoneal tumor inoculation ST2+ Tregs are mobilized and home to secondary dermal tumors. To test whether the ST2+ Tregs were responsible for preventing secondary dermal tumors, we inoculate mice lacking ST2 (ST2−/−) with peritoneal tumors and challenged them with dermal tumors; interestingly, we found that secondary dermal tumors where rejected in ST2−/− mice whereas tumors in wild type mice continue to grow. Finally, to corroborate our findings we used a mouse strain that develops spontaneous ovarian tumors that metastasize to the omentum. By treating these mice with anti-ST2 we observed a reduction in tumor weight, decrease in ST2+Tregs and an increase in tumor specific CD8+ cells in omentum and ovaries. Together these data suggest that omental ST2+ Tregs have an important role promoting and maintaining tolerance in tumor metastasis.
A Solid State Nitrogen Gas Generating Chip and Applications for Picosatellites (2011)

A microscale gas generating chip has many applications; in this study, applications relating to picosatellites have been considered. Cube satellites, a type of picosatellite, are of mass around one kilogram and side length 10cm x 10cm x 10cm. Their launches are becoming more numerous since their debut ten years ago. Their low cost and deployment system makes space accessible to agencies hitherto barred from it, such as universities and small governments. However, their power, mass, and volume budget is extremely tight. A microscale gas chip could compete with other designs for attitude control devices, most not flown yet as cube satellites are a new technology. Secondly, as pico and nanosatellite launches become more numerous, there is a concern that they will flood space with debris which will damage other, more valuable articial satellites. Recognizing this problem, international and US standards limit the lifetime of a cube satellite to 25 years after end of mission. Again, a low mass, power, and volume device is required in a cube satellite to deorbit and not take valuable resources away from a scientific payload. A MEMS (micro-electro-mechanical systems) chip for attitude control, with impulse bit on the order of uNs and total impulse of tens of mNs per square centimeter, is presented. Also presented is a hybrid printed circuit board (PCB) and microfabricated chip suitable for inflation of a deorbiting balloon. This has advantages in mass and volume over a pressurized gas chamber. The chip functions by decomposition of solid sodium azide by an addressable heater array. Arrays of square wells, filled with propellent, of side lengths from 50 micrometers to 1 centimeter were fabricated. Heater arrays of up to 10x10 were fabricated and the feasibility of large (500x500) arrays is discussed. Considering the volume the gas would take at standard temperature and pressure, the microscale chip would produce gas amounts on the order of milliliters per square centimeter, releasable in microliters, requiring milliWatts. The larger, PCB-based chip produced tens of milliters of gas from a 1.25" x 1.25" x 0.07" chip, requiring 10 Watts of power for tens of seconds to actuate.
Advanced Remedial Methods for Metals and Radionuclides in Vadose Zone Environments (2010)

Functionally, the methods for addressing contamination must remove and/or reduce transport or toxicity of contaminants. This problem is particularly challenging in arid environments where the vadose zone can be up to hundreds of feet thick, rendering transitional excavation methods exceedingly costly and ineffective. Delivery of remedial amendments is one of the most challenging and critical aspects for all remedy-based approaches. The conventional approach for delivery is through injection of aqueous remedial solutions. However, heterogeneous vadose zone environments present hydrologic and geochemical challenges that limit the effectiveness. Because the flow of solution infiltration is dominantly controlled by gravity and suction, injected liquid preferentially percolates through highly permeable pathways, by-passing low-permeability zones which frequently contain the majority of the contamination. Moreover, the wetting front can readily mobilize and enhance contaminant transport to underlying aquifers prior to stabilization. Development of innovative, in-situ technologies may be the only way to meet remedial action objectives and long-term stewardship goals. Shear-thinning fluids (i.e., surfactants) can be used to lower the liquid surface tension and create stabile foams, which readily penetrate low permeability zones. Although surfactant foams have been utilized for subsurface mobilization efforts in the oil and gas industry, so far, the concept of using foams as a delivery mechanism for transporting reactive remedial amendments into deep vadose zone environments to stabilize metal and long-lived radionuclide contaminants has not been explored. Foam flow can be directed by pressure gradients, rather than being dominated by gravity; and, foam delivery mechanisms limit the volume of water (&amp;lt; 20% vol.) required for remedy delivery and emplacement, thus mitigating contaminant mobilization. We will present the results of a numerical modeling and integrated laboratory-/intermediate-scale investigation to simulate, develop, demonstrate, and monitor (i.e. advanced geophysical techniques and advanced predictive microbial markers) foam-based delivery of remedial amendments to remediate metals and radionuclides in vadose zone environments.
THE ARCA OF IRIS: A NEW MODULAR & SCALABLE DIGITAL AERIAL IMAGING SENSOR ARCHITECTURE (2009)

There is growing demand in the geoimaging industry for all types of imagery and data collection with more efficient and economical technology. Aerial imaging sensor users have the challenge of rising operational costs and many of the sensors in the market today are single task or single mission oriented –not to mention very costly, with proprietary monolithic architectures and with a high rate of obsolescence. So new sensor systems are needed; systems that can also be flown at the same altitude and conditions of other optical or non-optical sensors (comounted and co-registered) to save time and expense; systems that open up new business opportunities and turn into reality the paradigm of “geoimaging the world online”. This paper introduces such new sensor, the ARCA (“Arched Retinal Camera Array”) of Iris (Integrated Retinal Imaging System); a new, modular and scalable digital aerial imaging sensor architecture. Based on U.S. Pat. Application No. 11/805,109, as a divisional application of U.S. Pat. App. No. 10/229,626- the ARCA sensor architecture along with being photogrammetrically compliant and scalable from small, to medium to large frame format, is a “Lego-like, plug & play” architecture which yields an unprecedented sensor configuration that is smaller, lighter, faster and economical.
Acute Acetaminophen Intoxication (1978)

Acetaminophen is a readily available, widely used drug which has been thought safer than aspirin. Overdosage which may result in fatal hepatic necrosis is commonly seen in the United Kingdom but is rarely reported in the United States. In a two-month period, three patients were admitted to a general hospital because of acetaminophen overdose, suggesting that this problem may occur more commonly than expected. They were successfully treated with N-acetylcysteine. Our experience in management of these three patients is presented and the pertinent literature concerning diagnosis and treatment of acute acetaminophen intoxication in briefly reviewed.
The selective catalytic reduction reaction and mechanism of citric acid modified the CeO2-WO3/TiO2 catalyst (2022)

In this study, the CeO2-WO3/TiO2-n catalyst was synthesized by co-precipitation method with citric acid and the selective catalytic reduction (SCR) performance of citric acid modified CeO2-WO3/TiO2 catalyst was studied. The results demonstrated that compared with CeO2-WO3/TiO2 catalyst, CeO2-WO3/TiO2-6% catalyst has been widened about 30°C in the temperature range of 80% and 90%, respectively, and the highest denitration efficiency was 98.83% at 350°C. Additionally, citric acid formed complex with WO3 and CeO2 and three carboxylic acid groups can improve the stability of WO3 to inhibit the growth of TiO2 and CeO2 crystallites, thus promoting the dispersion of CeO2 and the formation of Ce-O-W solid solution. Furthermore, the strong interaction between CeO2 and WO3 in CeO2-WO3/TiO2-6% catalyst will release more Oα and Ce3+. Citric acid promoted the interaction of unsaturated W atoms and hydroxyl groups adsorbed on unsaturated W atoms, thus providing more Lewis and Brönsted acid sites on the catalyst surface
Bifunctional Paramagnetic and Luminescent Clays Obtained by Incorporation of Gd3+ and Eu3+ Ions in the Saponite Framework (2021)

A novel bifunctional saponite clay incorporating gadolinium (Gd<sup>3+</sup>) and europium (Eu<sup>3+</sup>) in the inorganic framework was prepared by one-pot hydrothermal synthesis. The material exhibited interesting luminescent and paramagnetic features derived from the co-presence of the lanthanide ions in equivalent structural positions. Relaxometry and photoluminescence spectroscopy shed light on the chemical environment surrounding the metal sites, the emission properties of Eu<sup>3+</sup>, and the dynamics of interactions between Gd<sup>3+</sup> and the inner-sphere water placed in the saponite gallery. The optical and paramagnetic properties of this solid make it an attractive nanoplatform for bimodal diagnostic applications.
A cooperative approach to support software deployment using the software dock (1999)

Software deployment is an evolving collection of interrelated processes such as release, install, adapt, reconfigure, update, activate, deactivate, remove, and retire. The connectivity of large networks, such as the Internet, is affecting how software deployment is performed. It is necessary to introduce new software deployment technologies that leverage this connectivity. The Software Dock framework creates a distributed, agent based deployment framework to support the ongoing cooperation and negotiation among software producers themselves and among software producers and software consumers. This deployment framework is enabled by the use of a standardized deployment schema for describing software systems, called the Deployable Software Description (DSD) format. The Software Dock also employs agents to traverse between software producers and consumers in order to perform software deployment activities by interpreting the descriptions of software systems. The Software Dock infrastructure allows software producers to offer their customers high level deployment services that were previously not possible.
Application of stochastic inverse theory to ionospheric tomography (1992)

Tomographic processing of path integral electron density records is emerging as a viable tool for ionospheric research. Tomographic processors fall into at least two major classes: those applying the Radon transform and those employing linear algebraic matrix inversion. In this paper we apply one of the latter, the “weighted, damped, least squares” technique of stochastic inversion, to two simulated but realistic data sets. This method, which repeatedly has been applied successfully to ocean acoustic tomography, is particularly suited to solving inverse problems in geophysics because it provides an orderly mechanism for judicious use of a priori or external information to complement sparse or nonuniform path integral data. The limited range of angles through which the ionosphere may be viewed on satellite‐to‐ground paths represents such a nonuniformity in ionospheric tomography. The method also provides means for estimating uncertainty in the image field, uncertainty which itself is nonuniform.
Studies on Cytotoxic Effects of Brown Coal Dusts (1999)

Brown coal resources abound in China. There are many people working on exploiting and using it. To evaluate the cytotoxicity and pathogenic effect of brown coal dusts, the main compositions, dutotoxicity in vitro and damage to rats' lung were investigated with the dusts collected in two coal mines.
An Optimum Design Index of the Bottle with the Vacuum Insulation Structure (2011)

In this paper, we present an optimum design index of the bottle with a vacuum insulation structure. Thinner wall design is required to produce lighter bottles. When the wall thickness is too thin, the bottles crushed external pressure. Therefore it is necessary to provide the optimum design index of the bottle. We showed the factors that may affect on the deformation of bottles. We though the factors are classified into shape and material of the bottle. The factors in shape are length L, diameter D and thickness t of the bottles. And the factors for material are Young’s modulus and yield stress. The influence of each factor the critical deformation of bottles was verified by using FEM simulation. The nonlinear structural analysis LS‐DYNA of the analytical software was applied. The analytical model simplified the base of the external cylinder is hollow cylinder model with shell element. Material properties for stainless steel (sus304), commercially pure titanium (Ti) and titanium alloy (Ti‐6Al‐4V). These each analytical model was loaded an external pressure by time steps. The pressure when the analytical model was transformed then was obtained. The result shows that the bottle’s strength has the definite relation from its shape and greatly influences the material rigidity.
Two rapid pigmentation tests for identification of Cryptococcus neoformans (1982)

Two tests were developed for the rapid identification of Cryptococcus neoformans based on pigment produced by the organism's phenoloxidase activity. Caffeic acid was incorporated into cornmeal agar, a medium used routinely for yeast identification. When tested on this medium, only C. neoformans isolates produced brown pigment. All other yeasts maintained their normal morphology and did not produce the reaction product. A non-medium-based test was developed for same-day identification of C. neoformans isolates. Paper strips saturated with a buffered L-beta-3,4-dihydroxyphenylalanine-ferric citrate solution were inoculated with isolates and incubated at 37 degrees C. Pigment production occurred only with C. neoformans isolates, many within 60 to 90 min. All other yeasts remained negative.
Development of a Rapid Latex Enhanced Turbidimetric Assay for Retinol Binding Protein in Urine (1991)

We describe a simple, rapid and sensitive homogeneous immunoassay for urinary retinol-binding protein (RBP) using latex particle-enhanced turbidimetric immunoassay. Rabbit anti-human RBP is covalently coupled to 40 nm latex particles and the assay performed on the IL Monarch 2000 centrifugal analyser, with a 20 microL sample volume and the reaction monitored at 340 nm over an 8 min period. The assay range is 0-6 mg/L with a detection limit of 25 micrograms/L. The within and between assay coefficients of variation are less than 1.5% and less than 2.5%, respectively. Comparison with radioimmunoassay for RBP showed good agreement.
Measurement of Local Phase Holdups in a Two- and Three-Phase Bubble Column (2000)

A new invasive sensing probe for the measurement of local phase holdups in two- and three-phase reactors is described. The local gas and solids holdups in a bubble column with a volume of V = 2 m3 at varying operating conditions (gas velocity, sparger design, solids content and density) are measured by means of differential pressure measurement in combination with either time domain reflectometry or electrical conductivity measurement. The phase distribution profiles at two- and three-phase operating conditions are described. The influence of the sparger design on the shape of these profiles, the influence of the solid phase on the gas distribution, the solids distribution and the gas-stow effect above the sparger because of a dense particle layer are capable of experimental proof for the first time.
Semiconductor optical amplifiers for microwave photonics links (2003)

The influence of saturated Semiconductor Optical Amplifiers "SOA" (classical or gain clamped) on the transmission characteristics of a fibre optical link carrying a microwave signal is presented. SOAs present different behaviour in term of gain, nonlinearity, frequency response and noise in accordance with the modulation frequency of the input signal.
Research on Railway Coach Electric Safety Monitoring System (2009)

Railway coach system has been developed from simple and single to integrated and intelligent electric devices. Now, as PLC system has failed to meet the requirement of rapid development of coach system because of its resource constraints, in order to overcome limitation of the current system, improve the integral performance and central control, realize uniform control and information platform, the system architecture of railway coach electric safety monitoring system is put forward in the paper, and relevant hardware and software system is designed. The system has been applied to the Chinese 25T train, and also can operate in other public transport such as metro subway, light rail, and MARC train.
External Fixation Diastasis Management of Kohler's Disease in a 14-Year-Old Boy: A Case Report (2020)

A case presentation of an adolescent with tarsal navicular avascular necrosis is presented. External fixation with tarsal navicular diastasis is a simple, straightforward management option to allow osseous regrowth and bone healing. In this case, the external fixator was well tolerated and the patient demonstrated a quick return to function without pain or discomfort. The external fixation technique with tarsal navicular diastasis is an uncommon but effective means of reversing the tarsal navicular avascular process and avoiding an open technique such as arthrodesis.
Updated prevalence of monogenic diabetes in Australia: Fremantle Diabetes Study Phase 2 (2019)

Medical Journal of AustraliaVolume 211, Issue 4 p. 189-189.e1 Letters Updated prevalence of monogenic diabetes in Australia: Fremantle Diabetes Study Phase 2 Timothy ME Davis, Corresponding Author tim.davis@uwa.edu.au University of Western Australia, Perth, WASearch for more papers by this authorAshley E Makepeace, Fiona Stanley Hospital, Perth, WASearch for more papers by this authorKirsten Peters, University of Western Australia, Perth, WASearch for more papers by this authorKevin Colclough, Molecular Genetics Laboratory, Royal Devon and Exeter NHS Foundation Trust, Exeter, UKSearch for more papers by this authorWendy A Davis, University of Western Australia, Perth, WASearch for more papers by this author Timothy ME Davis, Corresponding Author tim.davis@uwa.edu.au University of Western Australia, Perth, WASearch for more papers by this authorAshley E Makepeace, Fiona Stanley Hospital, Perth, WASearch for more papers by this authorKirsten Peters, University of Western Australia, Perth, WASearch for more papers by this authorKevin Colclough, Molecular Genetics Laboratory, Royal Devon and Exeter NHS Foundation Trust, Exeter, UKSearch for more papers by this authorWendy A Davis, University of Western Australia, Perth, WASearch for more papers by this author First published: 18 July 2019 https://doi.org/10.5694/mja2.50290Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume211, Issue4August 2019Pages 189-189.e1 RelatedInformation
Time-absorbance profile ratio background correction: introducing TAP to correct for spectral overlap in high-resolution continuum source graphite furnace atomic absorption spectrometry (2021)

A new method to correct for spectral overlap when using HR CS GFAAS is proposed.
Ideology and Linguistic Theory (2013)

In The Ideological Structure of Linguistic Theory Geoffrey J. Huck and John A. Goldsmith provide a revisionist account of the development of ideas about semantics in modern theories of language, focusing particularly on Chomsky's very public rift with the Generative Semanticists about the concept of Deep Structure.
Aggrecanase cleavage in juvenile idiopathic arthritis patients is minimally detected in the aggrecan interglobular domain but robust at the aggrecan C‐terminus (2012)

Aggrecanases appear to cleave minimally in the interglobular domain of aggrecan in JIA patients despite robust levels of cleavage in the chondroitin sulfate-rich region. These results suggest that in JIA, unlike other arthritides, aggrecanase cleavage in the aggrecan interglobular domain might not be a major pathogenic event.
Enhanced crystallization of poly(L-lactide-co-ɛ-caprolactone) during storage at room temperature (2000)

Copolymer of L-lactide and ε-caprolactone [P(LLA-CL)] (50/50) was synthesized using stannous octoate and was stored at room temperature. The change in physical properties occurring during this storage at room temperature was investigated by differential scanning calorimetry (DSC), X-ray diffractometry, polarizing optical microscopy, tensile and bending tests, and light absorbance measurements. It was concluded that the increase in mechanical properties and light absorbance during storage can be ascribed to gradual selective crystallization of the L-lactide sequence in P(LLA-CL) at room temperature. © 2000 John Wiley & Sons, Inc. J Appl Polym Sci 76: 947–953, 2000
Influence of Excitation Frequency, Phase Shift, and Duty Cycle on Cooling Ratio in a Dynamically Forced Impingement Jet Array (2020)

Abstract The cooling ratio on a dynamically forced 7 × 7 impingement jet array is studied experimentally. The current study is focused on determining the influence of a phase shift between every row of nozzles as well as the impact of a duty cycle variation on the cooling ratio. Both parameters are studied in dependency of the impingement distance (H/D = 2, 3, 5), the (nozzle-) Reynolds-number (ReD = 3200, 5200, 7200), and the excitation frequency (f = 0 Hz − 1000 Hz). For every set of parameters, the phase shift between every row of nozzles is varied between Φ=0% and 90%, while the variation of the duty cycle is performed between duty cycle (DC) = 35% and 65%. During all investigations, the dimensionless distance between adjacent nozzles is fixed at Sx/D = Sy/D = 5, and liquid crystal thermography is used to acquire the wall temperatures, which are further processed to calculate the local Nusselt numbers. Generally, the implementation of an excitation frequency allows a case-depending increase in the cooling ratio of up to 52%. Further implementation of a phase shift yields an additional frequency-depending improvement of the cooling ratio. In case of duty cycle variation, the best case revealed an additional 19% improvement in the cooling ratio.