gebhart/patrepeval huggingface dataset:
A soluble Nogo receptor differentially affects plasticity of spinally projecting axons (2004)

In the central nervous system, regeneration of injured axons and sprouting of intact axons are suppressed by myelin-derived molecules that bind to the Nogo receptor (NgR). We used a soluble form of the NgR (sNgR), constructed as an IgG of the human NgR extracellular domain, to manipulate plasticity of uninjured primary afferent and descending monoaminergic projections to the rat spinal cord following dorsal rhizotomy. Rats with quadruple dorsal rhizotomies were treated with intrathecal sNgR or saline, or were left untreated for 2 weeks. Rhizotomy alone resulted in sprouting of serotonergic axons and to a lesser extent, tyrosine-hydroxylase (TH)-expressing axons, while axons expressing dopamine-beta-hydroxylase (DbetaH) were unaffected. Human IgG immunohistochemistry revealed that sNgR infused into the intrathecal space penetrated approximately 300 microm into spinal white and grey matter. Separate axonal populations differed in their responses to intrathecal sNgR: TH-expressing and DbetaH-expressing axons responded most and least vigorously, respectively. Serotonergic axons were identified by serotonin (5-HT) or serotonin transporter (SERT) immunohistochemistry. Interestingly, a large increase in 5-HT compared to SERT-positive axons density in both saline and sNgR-treated rats indicated that serotonergic axons both sprouted and increased their transmitter content in response to rhizotomy and sNgR treatment. Calcitonin gene-related peptide-positive axons were largely depleted ipsilaterally by rhizotomy, and sNgR increased axon density only in deeper contralateral laminae (III-V). GAP-43 immunohistochemistry revealed a small increase in axon density following dorsal rhizotomy that was further augmented by sNgR treatment. These results reveal a differential effect of myelin antagonism on distinct populations of spinally projecting axons.
UAE mapped attenuation at RF frequencies (UAE-MARF) (2009)

This paper develops both theoretical and experimental models for the prediction of attenuation and reflectivity of satellite signals at Ku-band in the UAE. The theoretical model gives a detailed study on the effect of the attenuation and the reflectivity due to the increase of the frequency or the density of different hydrometers. The experimental model, which is based on actual measurements obtained from NASA, was used to extract the required precipitation radar (PR) products. By applying the image analysis techniques on the PR data for one whole year (2000), a graphical representation of attenuation at Ku-band in the UAE was obtained. Results of this paper are vital for the successful design of satellite TV broadcast systems in the UAE operating at Ku-band.
Épidémiologie de la méningococcie invasive au Canada, 2012 à 2019 (2022)

Contexte : Divers programmes de vaccination contre le méningocoque chez les enfants et les adolescents utilisant des vaccins conjugués monovalents (sérogroupe C) et quadrivalents (A, C, Y, W) ont été mis en œuvre au Canada depuis 2002, ce qui a entraîné une diminution de la méningococcie invasive (MI), en particulier chez le sérogroupe C. Les vaccins contre le méningocoque ont également été utilisés pour la lutte contre l’éclosion, notamment le à plusieurs composants contre le sérogroupe B. Le présent article décrit l’épidémiologie de la MI au Canada de 2012 à 2019. Méthodes : Les données sur les cas ont été obtenues du Système national de surveillance améliorée de la méningococcie invasive entre le 1er janvier 2012 et le 31 décembre 2019. Les isolats ont été envoyés au Laboratoire national de microbiologie pour la confirmation du sérogroupe et d’autres études, y compris l’identification du phénotype et du complexe clonal. Résultats : Au total, 983 cas de MI ont été signalés entre 2012 et 2019. Dans l’ensemble, l’incidence de la MI ajustée selon l’âge de 2012 à 2019 était de 0,34 cas par 100 000 habitants par année lorsqu’elle était normalisée à la répartition selon l’âge de la population canadienne de 2011 (IC à 95 % : 0,32 à 0,36). Les nourrissons de moins d’un an présentaient le taux d’incidence moyen le plus élevé selon l’âge (3,6 cas pour 100 000 habitants par année, IC à 95 % : 2,8 à 4,3). Le taux d’incidence ajusté selon l’âge le plus élevé a été associé au sérogroupe B (0,17 cas pour 100 000 habitants par année, IC à 95 % : 0,16-0,19). Avant 2015, la plupart des isolats de sérogroupe W invasif ont été identifiés comme étant le complexe clonal 22 (ST-22 CC) et l’augmentation du sérogroupe W au Canada au cours des dernières années a été associée au remplacement du ST-22 CC endémique par le ST-11 CC hypervirulent. Conclusion : La méningococcie invasive est une infection rare, mais grave au Canada qui touche surtout les très jeunes enfants. Le sérogroupe B continue de représenter la plus grande proportion de la maladie. Le sérogroupe W associé au virus ST-11 CC devient un contributeur croissant de maladies dans tous les groupes d’âge non protégés par les vaccins contenant le sérogroupe W.
Omitting a platysma muscle suture after cervicotomy for thyroid surgery reduces initial postoperative pain – a randomised controlled trail (2017)

Suturing the platysma muscle after thyroid surgery is frequently described in the literature. However, no prospective evidence exists for its use and benefit. The aim of this study was to evaluate how a platysma muscle suture impacts the initial postoperative pain after thyroid surgery.
Pentanuclear Complexes for a Series of Alkylzinc Carboxylates (2009)

In contrast to previously reported alkylzinc carboxylates based on aryl carboxylates, the reaction between diethylzinc and a series of zinc bis(alkyl carboxylate)s yields complexes with a ligand stoichiometry of carboxylate to ethyl of 3:2. The analytical data, including single-crystal X-ray diffraction, indicate that, for “ethylzinc acetate”, the product is an unusual pentameric complex of the form [Zn5(OAc)6(Et)4].
The use of wheelmotors to provide active steering and guidance for a light rail vehicle (2017)

Whilst conventional, rigid axle railway wheelsets are inherently simple, reliable and relatively inexpensive, they have well known limitations with regard to the competing requirements of steering and stability. A wide range of mechanical and mechatronic solutions have been proposed to overcome these limitations and to allow near-radial steering in sharp curves. This paper discusses some considerations in the design and development of wheelmotor active steering technology for light rail vehicles (LRVs), where each wheel incorporates a traction motor which can be driven independently of the other. This arrangement is considered to have some advantages over similar mechatronic approaches which use actuators in the primary longitudinal / yaw suspension.
Entanglement Assisted Metrology (2005)

We propose a new approach to the measurement of a single spin state, based on nuclear magnetic resonance (NMR) techniques and inspired by the coherent control over many-body systems envisaged by quantum information processing. A single target spin is coupled via the magnetic dipolar interaction to a large ensemble of spins. Applying radio frequency pulses, we can control the evolution so that the spin ensemble reaches one of two orthogonal states whose collective properties differ depending on the state of the target spin and are easily measured. We first describe this measurement process using quantum gates; then we show how equivalent schemes can be defined in terms of the Hamiltonian and thus implemented under conditions of real control, using well established NMR techniques. We demonstrate this method with a proof of principle experiment in ensemble liquid state NMR and simulations for small spin systems.
The Understanding of the Metazoan Skeletal System, Based on the Initial Discoveries with Siliceous and Calcareous Sponges (2017)

Initiated by studies on the mechanism of formation of the skeletons of the evolutionary oldest still extant multicellular animals, the sponges (phylum Porifera) have provided new insights into the mechanism of formation of the Ca-phosphate/hydroxyapatite skeleton of vertebrate bone. Studies on the formation of the biomineral skeleton of sponges revealed that both the formation of the inorganic siliceous skeletons (sponges of the class of Hexactinellida and Demospongiae) and of the calcareous skeletons (class of Calcarea) is mediated by enzymes (silicatein: polymerization of biosilica; and carbonic anhydrase: deposition of Ca-carbonate). Detailed studies of the initial mineralization steps in human bone-forming cells showed that this process is also controlled by enzymes, starting with the deposition of Ca-carbonate bio-seeds, mediated by carbonic anhydrases-II and -IX, followed by non-enzymatic transformation of the formed amorphous Ca-carbonate deposits into amorphous Ca-phosphate and finally hydroxyapatite crystals. The required phosphate is provided by enzymatic (alkaline phosphatase-mediated) degradation of an inorganic polymer, polyphosphate (polyP), which also acts as a donor for chemically useful energy in this process. These new discoveries allow the development of novel biomimetic strategies for treatment of bone diseases and defects.
Low-loss fiber-to-chip edge coupler for silicon nitride integrated circuits (2023)

Silicon nitride (SiN) integrated optical waveguides have found a wide range of applications due to their low loss, broad wavelength transmission band and high nonlinearity. However, the large mode mismatch between the single-mode fiber and the SiN waveguide creates a challenge of fiber coupling to these waveguides. Here, we propose a coupling approach between fiber and SiN waveguides by utilizing the high-index doped silica glass (HDSG) waveguide as the intermediary to smooth out the mode transition. We achieved fiber-to-SiN waveguide coupling efficiency of lower than 0.8 dB/facet across the full C and L bands with high fabrication and alignment tolerances.
Dietary protein-induced changes of the erythropoietin level in rat serum. (1985)

Erythropoietin, a glycoprotein, is the primary regulator of erythropoiesis. The most convenient and sensitive assay for active erythropoietin is to measure its stimulatory effect on in vitro 3H-thymidine incorporation into DNA of erythropoietin-responsive cells. An attempt with this method to estimate the erythropoietin level in rat serum, however, was unsuccesful because of the presence of inhibitory substance(s) and non-erythropoietic factor(s) stimulating 3H-thymidine incorporation. Pretreatment of the serum by heating, extraction of erythropoietin from denatured-protein aggregates, and subsequent concentration of erythropoietin in the extract with alcohol precipitation made it possible to measure the serum erythropoietin levels. Rabbit anti-erythropoietin antibody was used for a quantitative estimation of erythropoietin in the concentrated extracts. Erythropoietin levels in sera of rats fed on varied amounts of casein for 7 days were measured with these procedures to find if the impairment of erythropoiesis upon protein deprivation was due to changes in the erythropoietin level. We found that the level in protein-deprived rats was less than 1/8 that of 20% casein-fed rats, a level undetectable by the present assay, and that the serum erythropoietin increased as the protein content in the diet was increased up to 20%, then leveled off. The erythropoietin in serum decreased rapidly after protein deprivation; the level at 12hr after deprivation began was about 1/5 that in 20% casein-fed rats. Thus, the depression of erythropoiesis upon protein deprivation is primarily caused by the lowered level of erythropoietin.
Combined Magnesia, Ceria and Nickel Catalyst Supported over γ-Alumina Doped with Titania for Dry Reforming of Methane (2018)

This study investigated dry reforming of methane with combined catalysts supported on &amp;gamma;-Al2O3 support doped with 3.0 wt. % TiO2. The physicochemical properties of all the catalysts were determined by inductively-coupled plasma/mass spectrometry metal analysis, nitrogen physisorption, X-ray diffraction, temperature programmed reduction/desorption, thermogravimetric analysis, and scanning electron microscopy. The addition of CeO2 and MgO to Ni strengthened the interaction between the Ni and the support. The catalytic activity results indicated that the CeO2 and MgO addition to Ni did not do much in retarding carbon deposition, but they improved the activity of the catalysts. Among the tested catalysts, it was found that the catalyst with the composition of 5.0 wt % NiO-10.0 wt % CeO2/3.0 wt %TiO2-&amp;gamma;-Al2O3 resulted in the highest CH4 and CO2 conversion with H2/CO mole ratio close to unity. The optimum reaction conditions in terms of reactant conversion and H2/CO mole ratio were achieved by varying space velocity and CO2/CH4 mole ratio.
Macrophages of distinct origins contribute to tumor development in the lung (2018)

Tissue-resident macrophages can self-maintain without contribution of adult hematopoiesis. Herein we show that tissue-resident interstitial macrophages (Res-TAMs) in mouse lungs contribute to the pool of tumor-associated macrophages (TAMs) together with CCR2-dependent recruited macrophages (MoD-TAMs). Res-TAMs largely correlated with tumor cell growth in vivo, while MoD-TAMs accumulation was associated with enhanced tumor spreading. Both cell subsets were depleted after chemotherapy, but MoD-TAMs rapidly recovered and performed phagocytosis-mediated tumor clearance. Interestingly, anti-VEGF treatment combined with chemotherapy inhibited both Res and Mod-TAM reconstitution without affecting monocyte infiltration and improved its efficacy. Our results reveal that the developmental origin of TAMs dictates their relative distribution, function, and response to cancer therapies in lung tumors.
Cardiac sympathetic innervation network shapes the myocardium by locally controlling cardiomyocyte size through the cellular proteolytic machinery (2019)

It is widely appreciated that sympathetic stimulation of the heart involves a sharp increase in beating rate and significant enhancement of contractility. We have previously shown that, in addition to these evident functions, sympathetic neurons (SNs) also provide trophic input to cardiomyocytes (CMs), regulating cell and organ size. More recently, we have demonstrated that cardiac neurons establish direct interactions with CMs, allowing neuro-cardiac communication to occur locally, with a 'quasi-synaptic' mechanism. Based on the evidence that cardiac SNs are unevenly distributed throughout the myocardial walls, we investigated the hypothesis that CM size distribution reflects the topology of neuronal density. In vitro analyses of SN/CM co-cultures, ex vivo confocal and multiphoton imaging in clarified hearts, and biochemical and molecular approaches were employed, in both rodent and human heart biopsies. In line with the trophic effect of SNs, and with local neuro-cardiac communication, CMs, directly contacted by SNs in co-cultures, were larger than the non-targeted ones. This property reflects the distribution of CM size throughout the ventricles of intact mouse heart, in which cells in the outer myocardial layers, which were contacted by more neuronal processes, were larger than those in the less innervated subendocardial region. Such differences disappeared upon genetic or pharmacological interference with the trophic SN/CM signalling axis. Remarkably, CM size followed the SN distribution pattern in other mammals, including humans. Our data suggest that both the acute and chronic influence of SNs on cardiac function and structure is enacted as a result of the establishment of specific intercellular neuro-cardiac junctions.
Synthesis and characterization of ionic liquids containing copper, manganese, or zinc coordination cations (2011)

Copper-, manganese-, and zinc-based ionic liquids (Cu{NH(2)CH(2)CH(2)OH}(6)[CH(3)(CH(2))(3)CH(C(2)H(5))CO(2)](2) (2), Cu{NH(CH(2)CH(2)OH)(2)}(6)[CH(3)(CH(2))(3)CH(C(2)H(5))CO(2)](2) (3A), Cu{NH(CH(2)CH(2)OH)(2)}(6)[CF(3)SO(3)](2) (3B), Cu{NH(CH(2)CH(2)OH)(2)}(6)[(CF(3)SO(2))(2)N](2) (3C), Mn{NH(CH(2)CH(2)OH)(2)}(6)[CF(3)SO(3)](2) (4), and Zn{NH(2)CH(2)CH(2)OH}(6)[CF(3)SO(3)](2) (5)) are synthesized in a single-step reaction. Infrared data suggest that ethanolamine preferentially coordinates to the metal center through the amine group in 2 and the hydroxyl group in 5. In addition, diethanolamine coordinates through the amine group in 3A, 3C, and 4 and the hydroxyl group in 3B. The compounds are viscous (>1000 cP) at room temperature, but two (3C and 4) display specific conductivities that are reasonably high for ionic liquids (>20 mS cm(-1)). All of the compounds display a glass transition (T(g)) below -50 °C. The cyclic voltammograms (CVs) of 2, 3A, 3B, and 3C display a single quasi-reversible wave associated with Cu(II)/Cu(I) reduction and re-oxidation while 5 shows a wave attributed to Zn(II)/Zn(0) reduction and stripping (re-oxidation). Compound 4 is the first in this new family of transition metal-based ionic liquids (MetILs) to display reversible Mn(II)/Mn(III) oxidation and re-reduction at 50 mV s(-1) using a glassy carbon working electrode.
Effects of a prescribed fire on dissolved inorganic carbon dynamics in a nutrient-enriched Everglades wetland (2008)

The purpose of this study was to assess the short-term response of dissolved inorganic carbon (DIC) chemistry to a prescribed fire in a nutrient-enriched area of the Everglades. Surface water samples were analyzed for water temperature, pH, total carbon (TC) and DIC concentrations in the bum area, in addition to one upstream and two downstream stations, pre- and post-fire for a period of 14 weeks. Dissolved free carbon dioxide (CO 2 ), the partial pressure of CO 2 (pCO 2 ) and CO 2 flux between surface water and the atmosphere were calculated. Although a large amount of unburned litter remained in the burned area and an immediate increase in the DIC concentration was observed post-fire, the average DIC concentration at the bum area was only slightly higher than the upstream station and lower than the two downstream stations. Similarly, CO 2 concentrations and pCO 2 at the burn area were lower than those of the three control stations. The low CO 2 and pCO 2 immediately post-fire were likely attributed to the elevated pH due to the addition of basic ash. However, the continuously low CO 2 and pCO 2 were the combined results of high pH and increased CO 2 sequestration by the growth of periphyton triggered by increased availability of light and growth space. These factors also explain why the DIC concentration at the burn area did not show a dramatic increase after the fire. Overall, our results suggest that despite decreases in pCO 2 post-bum, this wetland continues to act as a net source of CO 2 to the atmosphere.
Development of a Deep-Hole Measuring System by Using Autocollimation Principle (3rd Report) (2008)

The measuring system for evaluating the accuracy of a deep hole is developed by using the autocollimation principle. The system consists of a measuring unit and an optical system for light reception. The measuring unit detects the displacement of a feeler on the basis of the autocollimation principle. The optical system for light reception receives the laser beam irradiated from the measuring unit. In this research, the measuring accuracy and repeatability error of the system are evaluated by measuring the roundness, cylindricity and straightness of 110-mm-diameter holes of a ring gage and machined hole. As a result, it is clarified that the accuracies of the roundness, straightness and cylindricity measured by the measuring system correspond well to those by the tester in terms of both shape and value and that the repeatability error of 10 measuring measurements of roundness of machined hole is ±0.4μm.
Balance and Harmony Through Connectedness (2002)

This article describes how Native American nurses facilitate and promote harmony and balance through connectedness. According to the Conceptual Framework of Nursing in the Native American Culture, connectedness is at the core of intentionality of Native American nurses. Connectedness occurs through the dynamics of an interdependent and interrelated relationship between the nurse and client. The worldview of Native Americans is illuminated and illustrated within the context of culturally congruent nursing interventions.
Measurement and parameter characterization of pseudo-resistor based CCIA for biomedical applications (2014)

This paper performs the detailed analysis and measurement of a pseudo-resistor based CCIA used for bio-potential signal acquisition. The pseudo-resistor is implemented with MOS transistors operating in deep sub-threshold region, whose characteristic is not well-modeled in simulation. The resistor value versus control voltage and the effect of leakage current at OPAMP input node are discussed and characterized in this paper. The tested chip consumes 1.3µA from a 1-V supply, and the total integrated noise from 0.5 to 100 Hz is 3.26µVrms. It achieves a noise efficiency factor of 14.6.
Analysis for Capon and MUSIC DOA estimation algorithms (2009)

Directional of arrival (DOA) estimation technology play an important role in enhancing the performance of adaptive arrays for mobile wireless communications. A number of DOA estimation algorithms have been developed during the year. In this paper we present the performance analysis and comparison for Capon and MUSIC DOA estimation algorithms with a uniform circular array. Our focuses were to unveil the relationship between the mean square estimation error (MSE) and system resolution with phase mismatch. Monte Carlo simulation study results have been presented to illustrate the dependence of MSE with the quality of array calibration. The dependence of MSAE on array element number was also studied.
Frangipani (1997)

article Frangipani: a scalable distributed file system Share on Authors: Chandramohan A. Thekkath Systems Research Center, Digital Equipment Corporation, 130 Lytton Ave, Palo Alto, CA Systems Research Center, Digital Equipment Corporation, 130 Lytton Ave, Palo Alto, CAView Profile , Timothy Mann Systems Research Center, Digital Equipment Corporation, 130 Lytton Ave, Palo Alto, CA Systems Research Center, Digital Equipment Corporation, 130 Lytton Ave, Palo Alto, CAView Profile , Edward K. Lee Systems Research Center, Digital Equipment Corporation, 130 Lytton Ave, Palo Alto, CA Systems Research Center, Digital Equipment Corporation, 130 Lytton Ave, Palo Alto, CAView Profile Authors Info & Claims ACM SIGOPS Operating Systems ReviewVolume 31Issue 5Dec. 1997 pp 224–237https://doi.org/10.1145/269005.266694Online:01 October 1997Publication History 250citation3,362DownloadsMetricsTotal Citations250Total Downloads3,362Last 12 Months148Last 6 weeks30 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Catalytic hydrazine disproportionation mediated by a thiolate-bridged VFe complex (2019)

A heterobimetallic VFe complex is demonstrated to catalyse hydrazine disproportionation with yields of up to 1073 equivalents of NH3 per catalyst, comparable to the highest turnover known for any molecular catalyst. Notably, the heterobimetallic complex is appreciably more active than monometallic analogues of the V and Fe sites, suggesting that bimetallic cooperativity may facilitate the observed catalysis.
Origin of trisomy: no evidence to support the ovarian mosaicism theory (2012)

This study found no evidence of fetal ovarian mosaicism for trisomies 16, 21 and 22.