gebhart/patrepeval huggingface dataset:
Limitations and Precautions in the Use of the Farnsworth‐Munsell Dichotomous D‐15 Test (2019)

All these factors affect the outcome of the test and need specification and implementation if the test is to be applied consistently and equitably. We recommend the following: practitioners should never rely on a single color vision test regardless of the color vision standard; lighting should be Tcp '' 6500 K and Ra > 90; illuminance levels should be between 200 and 300 lux if detection of color vision deficiency is a priority or between 300 and 1000 lux if the need is to test at the level where illuminance has minimal influence on performance; illuminance should be reported; time limits should be set between 1 and 2 minutes; repeat testing (beyond the specified test and one retest) should be carried out only with authorization; and initial and repeated results should be reported. A set of test instructions to assist in the consistent application of the test is provided in the Appendix.
An Investigation of Three-Phase Relative Permeability (1984)

ABSTRACT A critical review of all known experimental and mathematical methods to predict three-phase oil relative permeability is presented, and factors affecting laboratory relative permeability determination are discussed. Imbibition three-phase oil relative permeability have been generated for water-wet systems from Owen's and Archer's two-phase data using Nolen's and Naar and Wygal's models; and a comparison of these two models has been presented. Corey's correlation has been used to generate three-phase oil isoperms in a system where gas displaces oil and water using Donaldson and Dean's three-phase data. Predicted data from Corey's correlation has been compared with Donaldson and Dean's experimental three-phase oil isoperms. Large discrepancies are noticed, expecially at low oil saturations. This paper also gives a preliminary result of steady-state three-phase experimental work in progress. Studies have been conducted using refined non-polar oil, brine, and nitrogen gas. A modified Penn State method and Berea sandstone have been used. Apparatus has been assembled for such studies involving the flooding of the core with nitrogen while varying the saturations of oil and brine. Brine saturation is determined by electrical resistivity measurement, oil saturation is obtained gravimetrically, and the gas saturation is the difference of the pore volume and the total liquid saturation. The core holder allows simultaneous measurement of (1) resistivity by the four electrode method, and (2) pressure differential across the core while the fluids are flowing.
Natural Fusarium occurrence qualitative evaluation on cereals under conventional and organic system in the Czech Republic (2015)

Cereals are the most growing crops under organic conditions. Cereals are supposed to be a source of mycotoxins produced by Fusarium species. Our research was led to describe the differences among natural Fusarium species occurrence in two localities and two growing systems â organic and conventional. The main differences were observed among years and cereal species. No statistically significant differences were determined between localities and farming systems. Keywords: Fusarium natural occurrence, organic farming, conventional farming
Submerged fermentation of Lactobacillus rhamnosus YS9 for &#947;-aminobutyric acid (GABA) production (2013)

γ-Aminobutyric acid (GABA) is a major inhibitory neurotransmitter in central nervous system, and its application in drugs and functional foods has attracted great attention. To enhance production of γ-aminobutyric acid, Lactobacillus rhamnosus YS9, a strain isolated from Chinese traditional fermented food pickled vegetable, was grown under submerged fermentation. Its cultivation conditions were investigated. When culture pH condition was adjusted to the optimal pH of glutamate decarboxylase activity, culture of Lb. rhamnosus YS9 in medium supplemented with 200 mM of monosodium glutamate and 200 μM of pyridoxal phosphate (PLP), produced 187 mM of GABA.
Effect of sulfur and molybdenum levels on growth, nitrate‐assimilation, and nutrient con‐tent ofPhalaris (1995)

Abstract An experiment was conducted with Phalaris aquatica L. cv. Sirolan under hydroponic conditions in the glasshouse at constant temperature of 25°C and natural sunlight. Plants were grown in double pot system with four sulfur and three molybdenum levels along with all the major‐ and micro‐nutrient elements. There was increase in growth, nitrate‐reductase activity and contents of most of the nutrient elements at all levels of sulfur and 1.68 μ/L molybdenum. Molybdenum at 3.36 μg/L level inhibited growth and nitrate‐reductase activity and decreased concentration of nutrient elements in plant. The inhibitory effect of higher level of molybdenum is perhaps mediated through its role in the nitrate‐reductase. Notes Present address: Division of Plant Physiology, Indian Agricultural Research Institute, New Delhi 110012, India.
Neuropsychology of Depression, Edited by Shawn M. McClintock and Jimmy Choi, The Guilford Press, 2022 (2023)

Department of Psychiatry and Behavioral Sciences Medical University of South Carolina Charleston, South Carolina C.H.K. receives royalties from Cambridge University Press for Textbook of ECT, fees from UpToDate for writing/updating electroconvulsive therapy topics, and fees from Northwell Health for teaching in an electroconvulsive therapy course.
Arteriopatía cerebral autosómica dominante con infartos subcorticales y leucoencefalopatía (2019)

INTRODUCTION: CADASIL (Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy) is an autosomal dominant neurovascular disorder that causes ischemic subcortical stroke, migraine with aura, depression, apathy, and dementia. It have a variable prevalence (at least 2-10.7 per 100,000 adults) and is the most common cause of inherited stroke and vascular dementia in adults. CLINICAL CASE: Female patient aged 44 with a history of migraine with aura since age 25. Also, family history of migraine, stroke, death and disability in youngsters. She arrives with clinical picture of acute encephalopathy that begins with a migraine headache accompanied by vomiting, photophobia, scotoma and later fever and hallucinations. Brain MRI shows abnormalities such as several lacunar infarcts and T2 hyperintensities involving the white matter of the left anterior temporal pole. The EEG shows slow background. Diagnosis was confirmed with detection of eosinophilic inclusions in smooth muscle cell of dermic capillary of skin biopsy (osmophilic in transmission electronic microscopy). El diagnostico se confirmo al detectar inclusiones eosinofilas en las celulas musculares lisas de los capilares dermicos en la biopsia de piel (osmofilas en la microscopia electronica de transmision). CONCLUSIONS: The patient showed is the first confirmed case in Cuba with CADASIL. Unfortunately, because of similarities in clinical presentation and neuroimaging, this disorder is often misdiagnosed as multiple sclerosis and treated with immunomodulatory medications that confer risk without benefit.
Additions and Corrections - Palladium-Catalyzed Additions of Amines to Conjugated Dienes : Alteration of Behavior of (triphenylphosphine)palladium Catalysts with Amine Hydroiodide Salts (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAdditions and Corrections - Palladium-Catalyzed Additions of Amines to Conjugated Dienes : Alteration of Behavior of (triphenylphosphine)palladium Catalysts with Amine Hydroiodide SaltsRobert W. Armbuster, Michael M. Morgan, James L. Schmidt, Chun Man. Lau, Rose M. Riley, Daniel L. Zabrowski, and Harold A. DieckCite this: Organometallics 1986, 5, 8, 1755Publication Date (Print):August 1, 1986Publication History Published online13 July 2004Published inissue 1 August 1986https://pubs.acs.org/doi/10.1021/om00139a603https://doi.org/10.1021/om00139a603research-articleACS PublicationsRequest reuse permissionsArticle Views26Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Anti-HIV Activity of Standard Combined Antiretroviral Therapy in Primary Cells Is Intensified by CCR5-Targeting Drugs (2020)

The efficacy of combined antiretroviral therapy (cART) against HIV-1 is evidenced by reduction of plasma viremia, disease progression, viral transmission, and mortality. However, major challenges still remain in HIV-1 management, especially the emergence of resistant strains and the persistence of viral reservoirs, apparent after cART treatment interruption. Efforts are ongoing to explore the most effective means to intensify cART and successfully control residual viral replication. We anticipate that the reduction by cART of HIV-1 reservoirs could be further enhanced by combining cART with entry inhibitors and drugs that silence CCR5 expression. CCR5-targeting drugs are attractive option because of their low side effects when combined with other antiretroviral drugs. The concept that their inclusion would be effective has been supported by the reduction in two long terminal repeat unintegrated circular DNA, a marker for new infections, when CCR5-targeting drugs are added to standard antiretroviral treatment. This study is, in part, an extension of our previous study demonstrating greater preservation of human CD4+ T-cells and CD4+/CD8+ cell ratios in HIV-infected CD34+ NSG mice when CCR5-targeting drugs were included with standard cART. In this study, we treated HIV-1-infected cell cultures with cART or cART plus CCR5-targeting drugs (maraviroc and rapamycin). We found that treatment intensification with CCR5-targeting drugs led to a significant reduction of HIV-1 replication in peripheral blood ononuclear cells (PBMCs), as judged by measured viral DNA copies and p24 levels. Our data provide proof of principle for the benefit of adding CCR5-targeting drugs to traditional, standard cART to further lower viremia and subsequently reduce viral reservoirs in clinical settings, while potentially lowering side effects by reducing cART concentrations.
A Study on Welfare Schemes for Migrant Construction Workers in Karnataka (2020)

The rural economy has undergone drastic change. The irregular rain, fragmented land holding and profit less agricultural sector has forced the rural youths to migrate towards urban centres in search of better employment opportunities. The construction sector mostly informal and unorganized is the major sector that is attracting majority of migrant population. Most of the migrant workers do not register themselves under any organization and remain unorganized. Though there are many welfare schemes and welfare fund, the migrant labourers are unaware of the schemes available for their welfare. This paper tries to make an attempt towards the welfare schemes available in their favour. The awareness regarding the same among migrant workers and a brief study on the unutilized welfare fund. 107 labourers working in various construction sites in Bangalore were considered for the study.
[Pretreatment ALT level and histologic activity as predictors of HBeAg loss in lamivudine treatment for chronic hepatitis B]. (2004)

Pretreatment ALT levels and histologic activity were the most important predictors for response to lamivudine.
Random hole optical fibers (2004)

Conventional telecommunications fibers rely on a refractive index difference between the core and cladding region to confine light to the central core region. The refractive index difference is produced by different compositions of glass in the core and cladding regions. In contrast, holey optical fibers rely on an array of air holes in the cladding to confine light to the fiber core. Ordered hole fibers have been fabricated in the past by many groups by drawing an array of glass tubes stacked around a solid central core. These holes are ordered carefully into a predetermined array. In this paper, we describe a new technique to produce holes (or pores) in the cladding region, which are randomly distributed around the solid central core. These new fibers have been made by drawing a preform, consisting of a porous outer cladding region surrounding a solid central core region, into a fiber. A gas producing powder has been incorporated into the preform such that during the fiber drawing process, the pores are formed in-situ in the preform cladding region. This in-situ gas production method produces small diameter, long, thin tubular pores in the fiber. Controlling the processing parameters can control the physical dimensions and distribution of the pores in the fiber. In some of the preforms that have been prepared, the porous cladding region has been prepared by sol gel techniques. In other preforms, the pores have been introduced by a variety of different techniques. The preform fabrication process and fiber drawing process used to produce these new holey fibers as well as the results of the morphological study elucidating the size, shape and distribution of the porous phase are presented.
Occurrence OP the Spotted Bat at Reno, Nevada (1935)

Occurrence OP the Spotted Bat at Reno, Nevada Get access E. Raymond Hall E. Raymond Hall Museum of Vertebrate Zoology, University of California, Berkeley, California Search for other works by this author on: Oxford Academic Google Scholar Journal of Mammalogy, Volume 16, Issue 2, May 1935, Page 148, https://doi.org/10.1093/jmammal/16.2.148 Published: 01 May 1935
Electrocoagulation of Palm Oil Mill Effluent (2008)

Electrocoagulation (EC) is an electrochemical technique which has been employed in the treatment of various kinds of wastewater. In this work the potential use of EC for the treatment of palm oil mill effluent (POME) was investigated. In a laboratory scale, POME from a factory site in Chumporn Province (Thailand) was subjected to EC using aluminum as electrodes and sodium chloride as supporting electrolyte. Results show that EC can reduce the turbidity, acidity, COD, and BOD of the POME as well as some of its heavy metal contents. Phenolic compounds are also removed from the effluent. Recovery techniques were employed in the coagulated fraction and the recovered compounds was analysed for antioxidant activity by DPPH method. The isolate was found to have a moderate antioxidant activity. From this investigation, it can be concluded that EC is an efficient method for the treatment of POME.
Design of Complex Nano-Scale Systems Using Multi-Agent Simulations and Structure-Behavior-Function Representations (2012)

Recent trends in technology are challenging engineers to configure products at ever smaller scales. At the nano-scale, biological protein machines are commonly chosen as a power-source for a broad-range of nano-devices. This paper explores the challenges in designing these and similar systems, such as improving the emergent system performance that arises from the interactions of many stochastic components. We develop a domain-independent methodology, using multi-agent simulations as a means of modeling and predicting emergent system behavior across scales and structure-behavior-function representations for understanding and navigating the resulting design space. This methodology is validated with an application of synthetic myosin motor design at the nanoscale, with simulation results aligning well with the macroscopic performance of myosin-powered muscular contractions. The multi-agent simulation is implemented with myosins modeled as agents, allowing for the virtual design and experimentation of synthetic myosins with altered structures and mechanochemical behaviors. Four myosin populations are designed and simulated, with their emergent system performance determined by aggregating the contributions of each myosin agent over time. Although the multi-agent simulation successfully recreates the emergent behaviors of the myosins, it is difficult to draw conclusions about how each structural variation influences aggregate performance. SBF representations of the system are then developed to describe how the aggregate performance of the system is explainable in terms of myosin behaviors, which map directly to altered myosin structures. It is then demonstrated how an engineer may utilize these representations and experimental results to reason about, and configure a myosin system with optimal performance. The methodology is domain-independent, ensuring its extendibility to similar complex systems while aiding a designer in simplifying a complex physical phenomenon to a design space consisting of only a few critical parameters. The methodology is particularly suited for complex systems with many parts operating stochastically across scales, and should prove invaluable for engineers facing the challenges of biological nanoscale design, where designs with unique properties require novel approaches or useful configurations in nature await discovery.
Role of CB1 and CB2 cannabinoid receptors in the development of joint pain induced by monosodium iodoacetate (2012)

Joint pain is a common clinical problem for which both inflammatory and degenerative joint diseases are major causes. The purpose of this study was to investigate the role of CB1 and CB2 cannabinoid receptors in the behavioral, histological, and neurochemical alterations associated with joint pain. The murine model of monosodium iodoacetate (MIA) was used to induce joint pain in knockout mice for CB1 (CB1KO) and CB2 cannabinoid receptors (CB2KO) and transgenic mice overexpressing CB2 receptors (CB2xP). In addition, we evaluated the changes induced by MIA in gene expression of CB1 and CB2 cannabinoid receptors and μ-, δ- and κ-opioid receptors in the lumbar spinal cord of these mice. Wild-type mice, as well as CB1KO, CB2KO, and CB2xP mice, developed mechanical allodynia in the ipsilateral paw after MIA intra-articular injection. CB1KO and CB2KO demonstrated similar levels of mechanical allodynia of that observed in wild-type mice in the ipsilateral paw, whereas allodynia was significantly attenuated in CB2xP. Interestingly, CB2KO displayed a contralateral mirror image of pain developing mechanical allodynia also in the contralateral paw. All mouse lines developed similar histological changes after MIA intra-articular injection. Nevertheless, MIA intra-articular injection produced specific changes in the expression of cannabinoid and opioid receptor genes in lumbar spinal cord sections that were further modulated by the genetic alteration of the cannabinoid receptor system. These results revealed that CB2 receptor plays a predominant role in the control of joint pain manifestations and is involved in the adaptive changes induced in the opioid system under this pain state.
Application of anifHmicroarray to assess the impact of environmental factors on free-living diazotrophs in a glacier forefield (2011)

Glacier forefield environments are exposed to extreme and fluctuating climatic and nutritional conditions. The high diversity of free-living diazotrophic communities found in these environments indicates that nitrogen fixers are able to efficiently cope with such conditions. In this study, a nifH microarray was used to monitor changes in diazotrophic populations in the field over a season, in the presence or absence of plants and in 2 glacier forefields characterized by a different bedrock type (siliceous or calcareous), as well as at different temperatures (10 °C, 15 °C) and under different nitrogen fertilization regimes (0, 10, 40 kg N·ha(-1)·year(-1)) in laboratory systems. Population structures responded highly dynamically to environmental changes. Plant presence had the strongest impact, which decreased toward the end of the season and with high amounts of nitrogen fertilization. Temperature and nitrogen fertilization increases indirectly affected diazotrophic communities through their positive impact on plant growth. These results indicate strong carbon limitation in young glacier forefield soils. Phylotypes related to the genus Methylocystis strongly responded to environmental variations. These methanotrophic microorganisms, which are able to retrieve nitrogen and carbon from the atmospheric pool, are particularly adapted to the extreme nutritional conditions found in glacier forefields.
Dietary Curcumin Increases Antioxidant Defenses in Lung, Ameliorates Radiation-Induced Pulmonary Fibrosis, and Improves Survival in Mice (2010)

The effectiveness of lung radiotherapy is limited by radiation tolerance of normal tissues and by the intrinsic radiosensitivity of lung cancer cells. The chemopreventive agent curcumin has known antioxidant and tumor cell radiosensitizing properties. Its usefulness in preventing radiation-induced pneumonopathy has not been tested previously. We evaluated dietary curcumin in radiation-induced pneumonopathy and lung tumor regression in a murine model. Mice were given 1% or 5% (w/w) dietary curcumin or control diet prior to irradiation and for the duration of the experiment. Lungs were evaluated at 3 weeks after irradiation for acute lung injury and inflammation by evaluating bronchoalveolar lavage (BAL) fluid content for proteins, neutrophils and at 4 months for pulmonary fibrosis. In a separate series of experiments, an orthotopic model of lung cancer using intravenously injected Lewis lung carcinoma (LLC) cells was used to exclude possible tumor radioprotection by dietary curcumin. In vitro, curcumin boosted antioxidant defenses by increasing heme oxygenase 1 (HO-1) levels in primary lung endothelial and fibroblast cells and blocked radiation-induced generation of reactive oxygen species (ROS). Dietary curcumin significantly increased HO-1 in lungs as early as after 1 week of feeding, coinciding with a steady-state level of curcumin in plasma. Although both 1% and 5% w/w dietary curcumin exerted physiological changes in lung tissues by significantly decreasing LPS-induced TNF-alpha production in lungs, only 5% dietary curcumin significantly improved survival of mice after irradiation and decreased radiation-induced lung fibrosis. Importantly, dietary curcumin did not protect LLC pulmonary metastases from radiation killing. Thus dietary curcumin ameliorates radiation-induced pulmonary fibrosis and increases mouse survival while not impairing tumor cell killing by radiation.