gebhart/patrepeval huggingface dataset:
Multidimensional Imaging (2005)

Provides a broad overview of advanced multidimensional imaging systems with contributions from leading researchers in the fieldMulti-dimensional Imaging takes the reader from the introductory concepts through to the latest applications of these techniques. Split into 3 parts covering 3D image capture, processing, visualization and display, using 1) a Multi-View Approach and 2.) a Holographic Approach, followed by a 3rd part addressing other 3D systems approaches, applications and signal processing for advanced 3D imaging. This book describes recent developments, as well as the prospects and challenges in advances in imaging sciences and engineering such as 3D image sensing, 3D holographic imaging, imaging applications for bio-photonics and 3D image recognition. Advanced imaging systems incorporate knowledge from various fields. It is a complex technology that combines physics, optics, signal processing, and image capture techniques.Provides a broad overview of advanced multidimensional imaging systems with contributions from leading researchers in the field.Integrates the background, introductory material with new advances in 3D imaging and applications.Covers the most recent technologies such as high speed digital holography, compressive sensing, real-time 3D integral imaging, 3D TV, photon counting imaging.To be available as an enhanced ebook with added functionality of colour films showing the effects of advanced 3D applications such as 3D microscopy, 3D biomedical imaging and 3D for security and defense applications.Acts as a single source reference to the rapidly developing field of 3D imaging technology.Provides supplementary material on a companion website including video clips, examples, numerical simulations, and experimental results to show the theoretical concepts.With contributions from leading researchers from across these fields, Multi-dimensional Imaging is a comprehensive reference for the imaging technology research community.
Supplementary Figure Legends from Adenovirus Improves the Efficacy of Adoptive T-cell Therapy by Recruiting Immune Cells to and Promoting Their Activity at the Tumor (2023)

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From Embryonic Fascicles to Adult Tracts: Organization of Neuropile From a Developmental Perspective (1984)

We discuss ideas emerging from our studies on selective axonal fasciculation in the grasshopper embryo that have implications for the organization of the adult neuropile in insects and perhaps other animals. While one of our laboratories has been studying the embryonic development of the G neurone (in the mesothoracic segment) and its lineal homologues (in other segments), the other has been studying the morphology and physiology of this same neurone and its segmental homologues in the adult nervous system. Our embryonic studies show that the growth cone of the G neurone selectively fasciculates with the A/P fascicle in preference to all other longitudinal axon fascicles at it turns anteriorly. The homologues of G in other thoracic and abdominal segments fasciculate in this same bundle. However, early in their morphological differentiation, they reveal interesting segmental differences. Our studies on the adult nervous system show that the segmental homologues of the G neurone share many properties in common (e.g. axons in the LDT: lateral dorsal tract) while other features are quite different. The notion emerging from these studies is that a basic segmentally-repeated pattern arises during embryogenesis: a stereotyped axonal scaffold upon which growth cones faithfully fasciculate. Evolutionary plasticity allows the specialization of lineally equivalent neurones in different segments within the context of the neuropilar neighbourhood that they find themselves in as a consequence of their selective fasciculation.
Patient's safety and hospital administration. (2004)

In November 1999, the Institute of Medicine (IOM) reported that about 98,000 patients die in U.S.A. as the result of medical errors in hospitals each year. This critical issue of medical errors and patient's safety has received much attention in the world. Many countries including the USA, the United Kingdom, Australia, New Zealand and Japan, etc., have launched initiative programs to reduce medical errors and to improve patient's safety. In Taiwan the patient's safety program has started since February 2003 when a national patient's safety committee was established in the Department of Health (DOH), Executive Yuan, Taiwan. In November 2003, the National Health Research Institute (NHRI) of Taiwan has held a nationwide conference for health policy. The consensus how to reduce medical errors and to improve patient's safety was reached at this meeting.
Layerless fabrication with continuous liquid interface production (2016)

Despite the increasing popularity of 3D printing, also known as additive manufacturing (AM), the technique has not developed beyond the realm of rapid prototyping. This confinement of the field can be attributed to the inherent flaws of layer-by-layer printing and, in particular, anisotropic mechanical properties that depend on print direction, visible by the staircasing surface finish effect. Continuous liquid interface production (CLIP) is an alternative approach to AM that capitalizes on the fundamental principle of oxygen-inhibited photopolymerization to generate a continual liquid interface of uncured resin between the growing part and the exposure window. This interface eliminates the necessity of an iterative layer-by-layer process, allowing for continuous production. Herein we report the advantages of continuous production, specifically the fabrication of layerless parts. These advantages enable the fabrication of large overhangs without the use of supports, reduction of the staircasing effect without compromising fabrication time, and isotropic mechanical properties. Combined, these advantages result in multiple indicators of layerless and monolithic fabrication using CLIP technology.
A comparison of methods for extracting DNA from Coxiella burnetii as measured by a duplex qPCR assay (2011)

This study demonstrated that a simple column kit method is efficient to use for the detection of C. burnetii in clinical samples including the SCV.
A Series of Primary Alkylamine Borane Adducts C x H 2x+1 NH 2 BH 3 : Synthesis and Properties (2021)

Abstract Primary alkylamine borane adducts C x H 2x+1 NH 2 BH 3 (CxAB) are unconventional molecules that may offer great opportunities in chemistry owing to their dihydrogen H δ+ ⋅⋅⋅H δ− bonds. Herein, we focus on six CxAB (x=4, 6, 8, 10, 12, 14), synthesized by Lewis acid‐base reaction between the complex (CH 3 ) 2 S⋅BH 3 and the primary alkylamines. At ambient temperature, C4AB and C6AB are oily liquid, and the other adducts are crystalline solids. The melting temperatures of the CxAB linearly increase as a function of ln(x) due to stronger intermolecular Van der Waals forces between the alkyl chains, and they are higher by 20–40 °C than those of the amines due to dihydrogen H δ+ ⋅⋅⋅H δ− bonds between the NH 2 BH 3 heads. The occurrence of dihydrogen H δ+ ⋅⋅⋅H δ− bonds is further confirmed by molecular and structural analyses. This is discussed hereafter.
IL-23-mediated mononuclear phagocyte crosstalk protects mice from Citrobacter rodentium-induced colon immunopathology (2015)

Gut homeostasis and mucosal immune defense rely on the differential contributions of dendritic cells (DC) and macrophages. Here we show that colonic CX3CR1(+) mononuclear phagocytes are critical inducers of the innate response to Citrobacter rodentium infection. Specifically, the absence of IL-23 expression in macrophages or CD11b(+) DC results in the impairment of IL-22 production and in acute lethality. Highlighting immunopathology as a death cause, infected animals are rescued by the neutralization of IL-12 or IFNγ. Moreover, mice are also protected when the CD103(+) CD11b(-) DC compartment is rendered deficient for IL-12 production. We show that IL-12 production by colonic CD103(+) CD11b(-) DC is repressed by IL-23. Collectively, in addition to its role in inducing IL-22 production, macrophage-derived or CD103(-) CD11b(+) DC-derived IL-23 is required to negatively control the otherwise deleterious production of IL-12 by CD103(+) CD11b(-) DC. Impairment of this critical mononuclear phagocyte crosstalk results in the generation of IFNγ-producing former TH17 cells and fatal immunopathology.
Design of a Commercial SAGD Heavy Oil Project (1995)

Abstract CS Resources is currently undertaking the construction of an 800 m3/day (5,000 bpd) thermal project near Senlac, Saskatchewan. The Senlac Thermal Project will use a steam assisted gravity drainage (SAGD) process to recover as much as 3.2 е6 m3 (20 mmbbl) of 13°API oil from a Dina channel sand. This paper discusses some of the production and facility engineering issues arising in this full scale SAGD scheme. Compared to primary or conventional thermal operations, some of the unusual aspects are: very high injection and production rates from individual wells; the need to manage the large amount of heat in the production stream; and a pronounced interdependence between the various project components. Reservoir description, production forecasting, and facility optimization are briefly discussed.
Syndrome X: 6 years later. (1994)

Resistance to insulin-stimulated glucose uptake is a common phenomenon, occurring in approximately 25% of the population at large, and is associated with a number of conditions known to be risk factors for coronary heart disease (CHD). These include hyperinsulinaemia, abnormal glucose tolerance, non-insulin-dependent diabetes mellitus, increased plasma triglyceride and decreased high-density-lipoprotein cholesterol concentrations, smaller, denser low-density-lipoprotein particles, hypertension, and abnormalities of fibrinolysis. These abnormalities frequently occur in a cluster within individuals. Understanding the basis of these changes, as well as the interrelationships between them, will contribute substantially to future studies of the causes of CHD, and ultimately form the basis for the clinical management of insulin-resistant individuals.
Fine Mapping of Monoclonal Antibody Epitopes on Human von Willebrand Factor Using a Recombinant Peptide Library (1992)

A recombinant human von Willebrand factor (vWF) cDNA fragment library was constructed in lambda gt11 for the localization of anti-vWF monoclonal antibody epitopes. Twelve of 21 monoclonal antibodies screened identified epitopes expressed in lambda gt11 as beta-galactosidase fusion proteins. By sequence analysis, these antigenic determinants were localized to segments ranging from 17 to 105 amino acids in length. Four epitopes apparently shared by more than one antibody were identified, suggesting the presence of immuno-dominant epitopes within vWF. Monoclonal antibody C3, which blocks factor VIII (FVIII) binding to vWF, bound to the same epitope previously identified by a second monoclonal antibody which also blocks this function, suggesting that this region may be at or near the vWF/FVIII binding domain. Three antibodies recognize the same region within the vWF A2 repeat. Mutations near this region appear to be responsible for Type IIA von Willebrand's disease. The co-localization of these antibodies suggests that this domain might be exposed on the surface of vWF, consistent with its apparent increased sensitivity to plasma proteases.
Thebakuhansystem (1991)

This chapter traces the formation and the evolution of the bakuhan structure of government from the middle of the sixteenth century to the end of the eighteenth century. The political and social institutions that underlay the bakuhan polity had their origins in the unification movement of the last half of the sixteenth century, especially in the great feats of military consolidation and social engineering achieved by Toyotomi Hideyoshi during the last two decades of the century. The story of the rise of the Tokugawa family to become the foremost military house of Japan follows a pattern common among a whole class of active regional military families who competed for local dominion during the fifteenth and sixteenth centuries. The structure of power over which the Tokugawa shogun ultimately presided was conceived as a balance among several classes of daimyo and the interests of the shogun.
Spasmodic dysphonia and botulinum toxin: experience from the largest treatment series (2010)

Spasmodic dysphonia is a focal laryngeal dystonia, with adductor, abductor, mixed, respiratory and singer's types. Our series over 24 years includes 1300 patients. 82% are of the adductor type; 63% were female; 12% had a positive family history and 82.4% had a focal distribution. All of the patients were managed with varying degrees of success with individualised dosing of botulinum neurotoxin A injected into the laryngeal musculature under EMG guidance.
Therapies to Restore Consciousness in Patients with Severe Brain Injuries: A Gap Analysis and Future Directions (2021)

This personalized approach can be realized through rigorous clinical trial design and international collaboration, both of which will be essential for advancing the development of new therapies and ultimately improving the lives of patients with DoC.
Dendritic cells and myeloid leukaemias: plasticity and commitment in cell differentiation (2007)

Dendritic cells (DCs) are key antigen-presenting cells (APCs), which link innate and adaptive immunity, ultimately activating antigen-specific T cells. This review examines the relationship between the acute and chronic myeloid leukaemias and cells with DC properties. DCs are non-dividing terminally differentiated cells, and ex vivo leukaemic cells or cell lines show little similarity to DCs. However, many leukaemias differentiate further in response to defined stimuli, and retain a degree of lineage plasticity. Therefore, several studies have explored the response of leukaemic cells to the in vitro regimens used to differentiate ex vivo primary DCs. Recent data suggest that the most 'dendritic-like' cells can be derived from more undifferentiated myeloid leukaemias, such as the myelomonocytic Mutz-3 cell line. These findings have important implications for understanding the developmental origins of DCs, for harnessing the APC properties of this class of tumour to stimulate the therapeutic anti-tumour immunity, and for developing useful models for the study of human DC physiology and pathology. There is a strong rationale for further exploration of this class of tumour and its relationship to the normal DC.
Weakly Factorial Domains and Groups of Divisibility (1990)

An integral domain R is said to be weakly factorial if every nonunit of R is a product of primary elements.We give several conditions equivalent to R being weakly factorial.For example, we show that the following conditions are equivalent: (1) R is weakly factorial; (2) every convex directed subgroup of the group of divisibility of R is a cardinal summand; (3) if P is a prime ideal of R minimal over a proper principal ideal (x), then P has height one and (x)p n R is principal; (4) R = C\Rp , where the intersection runs over the height-one primes of R , is locally finite, and the i-class group of R is trivial.Throughout this note, R will be a commutative integral domain with identity having quotient field K. Suppose that R is a UFD.If S is a saturated multiplicatively closed subset of R, then S = {Xpx -pn\X a unit of R, n > 0, each (p) Y} for some subset Y X{X), where X{X) is the set of height-one prime ideals of R .Conversely, every such subset Y X{X) determines a saturated multiplicatively closed subset of R. If we set T = {Xpx -p"\X a unit of R , n > 0, each (p() G X(1) -Y}, then every nonzero element r of ii may be written uniquely up to units in the form r = st where s e S and t T. Stated in terms of the group of divisibility G(R) of R, (S) is a cardinal summand of G(R).In fact, (S) c (T) -G(R).(See the next paragraph for definitions.)Here G(R) is a cardinal sum of copies of Z, one for each height-one prime, and (S) is the sum of the cyclic summands corresponding to the primes from Y .The purpose of this paper is to characterize the integral domains with this property.We show that an integral domain R has the property that every convex directed subgroup of G(R) is a cardinal summand of G(R) if and only if every nonunit of R is a product of primary elements, that is, R is weakly factorial.Let R be an integral domain with quotient field K.The group of divisibility of R is the group G(R) = K*/U(R), where K* is the multiplicative group of K and U(R) is the group units of R. G(R) is partially ordered
A generalized lattice decoder for asymmetrical space-time communication architecture (2002)

We present a generalized sphere decoding (GSD) algorithm and its application for detecting information symbols in the case where one has a system with more inputs (symbols) than outputs or the opposite situation. We study the special case of a multi-antenna scenario in a cellular system with N antennas at the mobile and M/spl ges/N antennas at the base station. GSD reaches the maximum likelihood (ML) performance for both up and down link with a moderate complexity.
An image data compression method using extrapolative prediction‐discrete sine transform; in the case of two‐dimensional coding (1989)

Abstract This paper considers the highly efficient coding of the gray‐level image. The extrapolative prediction‐discrete sine transform scheme, which was previously proposed by the authors for the case of one‐dimensional coding, is extended to the case of two‐dimensional coding. In the proposed method, the image is partitioned into square blocks. The correlations among blocks are eliminated by applying the two‐dimensional extrapolative prediction for each block from the restored boundary pixel. The correla‐in the block is eliminated by applying the orthogonal transformation to the prediction errors. In this paper, the correlation function of the image is assumed as the isotropic exponential function, and a two‐dimensional extrapolative prediction method is derived, which can be realized as a simple manipulation. The transformation of the prediction errors is performed by the variable‐separation type two‐dimensional extrapolative prediction‐discrete sine transform, where the one‐dimensional extrapolative prediction‐discrete sine transform is applied to rows and columns. Then the rate‐distortion characteristic is calculated, indicating that the proposed method is useful. It is shown that the proposed method with 4 × 4 block size has almost the same coding efficiency as the discrete cosine transform coding with 16 × 16 block size. A computer simulation was made for the actual image, leading to a result validating the theoretical estimation. The proposed method requires less computation per pixel, compared with the discrete cosine transform coding. The method is especially useful from the viewpoint of hardware implementation, since the block size is as small as 1/16.
Optimization of High Efficiency Silicon Heterojunction Solar Cells Using Silane-Plasma Diagnostics (2010)

In silicon heterojunction solar cells, the passivation of the crystalline silicon wafer surfaces and fabrication of emitter and back surface field are all performed by intrinsic and doped amorphous silicon thin layers, usually deposited by plasma-enhanced chemical vapor deposition (PECVD). Since the properties of materials deposited by PEVCD are directly linked to the plasma properties, plasma diagnostics are very useful tools to optimize such devices. A novel diagnostic has been developed to measure in-situ the molecular silane depletion fraction in the plasma during deposition. It is found that the silane depletion strongly depends on the process parameters, and appears to be a relevant parameter for the quality of the passivating layers. Good passivation is indeed obtained from highly depleted silane plasmas. Based on this, layers deposited in a large-area PECVD reactor working at very high frequency (40.68 MHz) were optimized for heterojunction solar cells. All other fabrication steps were also fully industry compatible, using sputtering for transparent conductive oxide layers and screenprinting for the front grid. The best 2 x 2 cm2 cell shows a high open-circuit voltage of 717 mV, yielding a conversion efficiency of 20.3% (aperture area).
Urban expressway traffic flow modeling and control using artificial neural networks (2004)

From the viewpoint of macroscopical dynamic characteristics of urban expressway traffic flow, a commonly used macroscopic dynamic deterministic traffic flow model for traffic control is analysed, the neural network model for the urban expressway traffic flow is established and the urban expressway multi-variable neural control strategy with both the on-ramp control and the road speeds control is presented. This control strategy is a servo system where both state and control can be followed. Finally as an example, Hangzhou urban expressway is simulated and the result is satisfied.
Using public T cell responses to predict cytomegalovirus infection status in silico (VIR1P.1004) (2014)

Abstract The ability of a host’s adaptive immune system to address an incipient infection relies on the previous existence of T cells which have randomly generated an appropriate antigen-specific T cell receptor (TCR). The nature of V(D)J recombination ensures that despite the enormous space of potential TCRs, there are many TCR specificities that are common in the naïve T cell repertoires across individuals. Hence, many pathogenic antigens are known to induce a “public” T cell response, in which the same functional TCR is found to be immunodominant in multiple individuals. Despite historical limitations on sequencing depth and the limited size of investigational cohorts, previous work on public T cell responses has identified many individual examples of public T cell responses to diseases including CMV, EBV, influenza and others. Using high-throughput TCRβ sequencing, we performed deep characterization of the TCR repertoires of 650 healthy subjects (356 CMV- and 294 CMV+) to enable massively parallel discovery of public T cell responses to CMV. We have identified in one experiment hundreds of CMV-associated public T cell responses. Using cross-validation, we demonstrate that taken collectively public T cell responses to CMV contain enough information to predict CMV status in new subjects using TCR sequencing alone, showing for the first time that assaying the host adaptive immune system could be a valid diagnostic strategy in the context of infectious disease.
Noise performance of negative-resistance compensated microwave bandpass filters. Theory and experiments (2001)

This paper examines both theoretically and experimentally the dependency of in-band noise performance upon circuit and device parameters of microwave filters employing negative-resistance compensation. By neglecting the influence of the induced gate noise source, a general expression for evaluating the noise figure of a second-order active filter is derived as a function of design parameters such as the transistor's noise figure, inductor's quality factor, and filter's bandwidth. In addition, factors affecting the optimization of the overall noise figure of these filters are discussed. For verification, the measured performance of two 900-MHz experimental MESFET filters are included.