gebhart/patrepeval huggingface dataset:
Paludolactone: A new Eudesmanolide Lactone fromWedelia PaludosaDc. (Acmela Brasiliensis) (2004)

Phytochemical investigation of the whole plant of Wedelia paludosa (Acmela brasiliensis) furnished a new eudesmanolide lactone, named paludolactone (2), in addition to the known eudesmanolide (1), stigmasterol, kaurenoic and oleanolic acids. 1H- and 13C-NMR, and MS spectroscopic and elemental analyses were used for the structural elucidation of these compounds.
Synaptojanin-2 Binding Protein Stabilizes the Notch Ligands DLL1 and DLL4 and Inhibits Sprouting Angiogenesis (2013)

These data identify SYNJ2BP as a novel inhibitor of tip cell formation, executing its functions predominately by promoting Delta-Notch signaling.
ChemInform Abstract: Synthesis and Structure of Tetrameric German‐closo‐dodecaborate Silver Halides. (2011)

Abstract Compounds (III) and (VI) crystallize in the monoclinic space group C2/c with Z = 4 (single crystal XRD).
Environmentally assisted cracking in light water reactors: Semiannual report, October 1986-March 1987 (1987)

This progress report summarizes work performed by Argonne National Laboratory on environmentally assisted cracking in light water reactors during the six months from October 1986 to March 1987.
An interactive and probabilistic strategy for visualizing linear biological sequence motifs (2013)

Short functional patterns of nucleotides or amino acids, also known as motifs, are found ubiquitously on DNA, RNA, and protein sequences. These motifs often serve as molecular interaction beacons, thus providing a degree of specificity between the macromolecular interactions found in the seemingly stochastic cellular environment. To date, the most common means of visualizing biological sequence motifs has been through sequence logos (Figure 1, top). While sequence logos have been an effective means of motif visualization for a subset of biological patterns, several limitations, including the assumption of uniform background probabilities and the inability to visualize underrepresented sequences, have limited their effectiveness – particularly in the field of post‐translational modifications. Here we present the pLogo, or probability logo, a interactive and statistically based representation of sequence motifs (Figure 1, bottom). pLogos share a number of unique features including i) residue/nucleotide heights which approximate their statistical significance, ii) underrepresented residues/nucleotides which are depicted below the x‐axis, and iii) conditional probabilities which can be easily manipulated and visualized by users. A pLogo web server will be created at http://plogo.uconn.edu . This work was funded in part by grants from the UConn Research Foundation and Genomes to Life from the US DoE.
Enzymatic Xylose Release from Pretreated Corn Bran Arabinoxylan: Differential Effects of Deacetylation and Deferuloylation on Insoluble and Soluble Substrate Fractions (2010)

In the present work enzymatic hydrolysis of arabinoxylan from pretreated corn bran (190 degrees C, 10 min) was evaluated by measuring the release of xylose and arabinose after treatment with a designed minimal mixture of monocomponent enzymes consisting of alpha-L-arabinofuranosidases, an endoxylanase, and a beta-xylosidase. The pretreatment divided the corn bran material approximately 50:50 into soluble and insoluble fractions having A:X ratios of 0.66 and 0.40, respectively. Addition of acetyl xylan esterase to the monocomponent enzyme mixture almost doubled the xylose release from the insoluble substrate fraction and gave release of 1 mol of xylose/mol of acetic acid released, whereas addition of feruloyl esterase promoted release of only approximately 0.4 mol of xylose/mol of ferulic acid released. For the soluble substrate fraction up to 36% of the xylose could be released by the enzymatic treatment. Acetyl xylan esterase addition on top of the minimal monocomponent enzyme mixture resulted in liberation of up to 0.5 mol of xylose/mol of acetic acid released, whereas feruloyl esterase addition released 1 mol of xylose/mol of ferulic acid released from the soluble substrate. The results imply that on the insoluble material the acetyl xylan esterase was more important for the enzymatic degradation than feruloyl esterase, whereas on soluble arabinoxylan the feruloyl esterase seemed to be more important for the release of xylose.
Impact of Halo Implantation on the Lifetime Assessment in Partially Depleted SOI Transistors (2006)

This paper investigates the impact of the presence of a HALO implanted region on the lifetime analysis, based on a study of drain current switch-off transients. The latter were experimentally determined and compared with two-dimensional numerical simulations for PD SOI nMOSFET devices fabricated in a 0.13 mm CMOS technology. This study investigated for different channel lengths the drain current transient in relation with devices parameters such as the body potential, threshold voltage and the current density in the source/drain junctions. In the HALO devices the hole current density through the junctions between source/drain and body were not very significant, so that the influence of the junction is only due to the capacitive coupling between source/body and drain/body channel. For the channel length range studied (from 10 to 0.2mm), the transient time of HALO devices suffers from a 56% reduction. However, in the no HALO devices, there is beyond the capacitive coupling also a significant increase in the hole current density, causing a transient time reduction of 74%, for the same channel length range.
Medical Imaging of Microrobots: Toward In Vivo Applications (2020)

Medical microrobots (MRs) have been demonstrated for a variety of non-invasive biomedical applications, such as tissue engineering, drug delivery, and assisted fertilization, among others. However, most of these demonstrations have been carried out in <i>in vitro</i> settings and under optical microscopy, being significantly different from the clinical practice. Thus, medical imaging techniques are required for localizing and tracking such tiny therapeutic machines when used in medical-relevant applications. This review aims at analyzing the state of the art of microrobots imaging by critically discussing the potentialities and limitations of the techniques employed in this field. Moreover, the physics and the working principle behind each analyzed imaging strategy, the spatiotemporal resolution, and the penetration depth are thoroughly discussed. The paper deals with the suitability of each imaging technique for tracking single or swarms of MRs and discusses the scenarios where contrast or imaging agent's inclusion is required, either to absorb, emit, or reflect a determined physical signal detected by an external system. Finally, the review highlights the existing challenges and perspective solutions which could be promising for future <i>in vivo</i> applications.
Electronic speckle pattern interferometry (1980)

Electronic speckle pattern interferometry can provide high-speed, real-time holography for industrial research and inspection. This article discusses its basic principles, modes of operation and applications, and finally tries to assess its future importance for industry.
Session details: Session 6: Telepresence, Virtual, and Augmented Reality (2015)

No abstract available.
Dapagliflozin attenuates human vascular endothelial cell activation and induces vasorelaxation: A potential mechanism for inhibition of atherogenesis (2017)

These observations identify a potential role for dapagliflozin in the attenuation of atherogenesis and identify anti-inflammatory molecular mechanisms associated with these effects.
A summary of spacecraft avionics functions (2002)

Avionics systems perform many of the core functions of a spacecraft. Currently, these functions are performed by digital avionics. The functions performed by avionics can be divided into two groups: spacecraft information system functions and spacecraft avionics supported functions. The information system functions perform the formatting, transportation, or processing on the commands, telemetry, and other information that is handled by the spacecraft digital avionics. The avionics supported functions use nonavionics elements to perform the primary system function. However, these avionics supported functions require heavy interaction with the avionics systems. This paper discusses each of these functions.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
The Traveling Chain Transmission: A Novel Two-Speed Chain Drive (2003)

In an automatic transmission with planetary gearsets, several clutches are generally required to manage the speed-ratio transitions. Parasitic losses due to open clutches and the transmission pump reduce net transmission efficiency and negatively impact overall vehicle fuel economy. A novel dual-speed drive that does not require clutches to achieve a speed-ratio change has been devised as an alternative to the planetary gearset. In this paper we describe the basic drive concept and the design and testing of two prototypes that was undertaken at the General Motors R&amp;D Center.
Indexes (2002)

The appropriate use of indexes can turn an otherwise sluggish and recalcitrant application into a highly responsive and productive business tool. Unfortunately, the converse is also true. Scattering inappropriate indexes around an application without careful thought is perfectly capable of turning it into a lumbering behemoth that's not much use to anyone. Working out whether an index is appropriate, and how best to create it if it is, is something of an acquired skill — which this chapter will help you to acquire. We're first going to look at what goes on inside Oracle when you opt to create a simple one, and then use that information to see how the additional index features available in recent Oracle releases can best be harnessed. During the course of the chapter we'll look at: What are indexes Indexes in Oracle Knowing the value and the cost of indexes Indexing multiple columns, key compression, skip scanning, and reverse key indexes Some myths of indexing Function-based indexes Bitmap and Bitmap Join indexes KeywordsLeaf NodeUnique ConstraintExecution PlanBranch NodeFull TableThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Surface parameter estimation using interferometric and polarimetric SAR (2003)

In this work the potential of using the interferometric coherence at different polarisations over surface scatterers in order to extract information about surface parameters is investigated. The sensitivity of the individual coherence contributions to surface roughness and moisture conditions is discussed and simulated using a polarimetric surface scattering model. Finally, experimental airborne SAR data are used to demonstrate the discussed effects.
Converting far infrared image information to other physiological data (2000)

Skin temperature is determined by blood-flow rate, structure of subcutaneous tissue, and activities of the sympathetic nervous system, which regulate heat dissipation from the body surface. Because of this, we can noninvasively detect distributions of many physiological functions from thermal images of the skin surface obtained by far infrared (FIR) imaging. If we can describe equations by which we calculate values of some functions from skin temperature, we might be able to analyze pathophysiological abnormalities by remote sensing. However, it is clear that we cannot convert a thermal image into other physiological function images unless we eliminate influences of many environmental conditions, structural variations, and other physiological parameters of skin-surface temperature. One solution is to introduce some physical, chemical, or neurohumoral stress to a patient and then take time-sequential thermal images. Dynamic fluctuation of such physiological functions might be revealed by sequential thermal images taken after stress is applied. We analyzed the theoretical backgrounds to determine regional skin temperature and thus developed application software to carry out the process. This article discusses algorithms we developed for detecting static abnormality or transient change of some physiological functions such as skin blood-flow rate, blood volume in cutaneous and subcutaneous vascular beds, and activities of the sympathetic nervous system.
Ultrasonic density sensor - higher accuracy by minimizing error influences (2002)

The density of a liquid can be determined from the acoustic parameters speed of sound and acoustic impedance. Unwanted deposits in pipelines and on sensor surfaces or gas bubbles in the fluid are common problems in industrial applications of ultrasonic sensors. Results of experiments and simulations of thin layer deposits show a correlation of the time delay of the reflected echo signal and the product of layer impedance and time of flight through the layer. This can be used for layer detection and error correction. The influence of gas bubbles on frequency and amplitude of the speed of sound sensor signal is shown. A correction of the speed of sound measurement error is presented, in which signal reconstruction and processing is used.
Cholesterol modulates human intestinal sodium-dependent bile acid transporter (2004)

Bile acids are efficiently absorbed from the intestinal lumen via the ileal apical sodium-dependent bile acid transporter (ASBT). ASBT function is essential for maintenance of cholesterol homeostasis in the body. The molecular mechanisms of the direct effect of cholesterol on human ASBT function and expression are not entirely understood. The present studies were undertaken to establish a suitable in vitro experimental model to study human ASBT function and its regulation by cholesterol. Luminal membrane bile acid transport was evaluated by the measurement of sodium-dependent 3H-labeled taurocholic acid (3H-TC) uptake in human intestinal Caco-2 cell monolayers. The relative abundance of human ASBT (hASBT) mRNA was determined by real-time PCR. Transient transfection and luciferase assay techniques were employed to assess hASBT promoter activity. Caco-2 cell line was found to represent a suitable model to study hASBT function and regulation. 25-Hydroxycholesterol (25-HCH; 2.5 microg/ml for 24 h) significantly inhibited Na(+)-dependent 3H-TC uptake in Caco-2 cells. This inhibition was associated with a 50% decrease in the V(max) of the transporter with no significant changes in the apparent K(m). The inhibition in hASBT activity was associated with reduction in both the level of hASBT mRNA and its promoter activity. Our data show the inhibition of hASBT function and expression by 25-HCH in Caco-2 cells. These data provide novel evidence for the direct regulation of human ASBT function by cholesterol and suggest that this phenomenon may play a central role in cholesterol homeostasis.
Basic Behavior of Molecules and Ions in Acetic Anhydride (1958)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBasic Behavior of Molecules and Ions in Acetic AnhydrideC. A. StreuliCite this: Anal. Chem. 1958, 30, 5, 997–1000Publication Date (Print):May 1, 1958Publication History Published online1 May 2002Published inissue 1 May 1958https://doi.org/10.1021/ac60137a036Request reuse permissionsArticle Views165Altmetric-Citations70LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (451 KB) Get e-Alertsclose Get e-Alerts
On Technical Security Issues in Cloud Computing (2009)

The Cloud Computing concept offers dynamically scalable resources provisioned as a service over the Internet. Economic benefits are the main driver for the Cloud, since it promises the reduction of capital expenditure (CapEx) and operational expenditure (OpEx). In order for this to become reality, however, there are still some challenges to be solved. Amongst these are security and trust issues, since the user's data has to be released to the Cloud and thus leaves the protection-sphere of the data owner. Most of the discussions on this topics are mainly driven by arguments related to organizational means. This paper focuses on technical security issues arising from the usage of Cloud services and especially by the underlying technologies used to build these cross-domain Internet-connected collaborations.
A novel single-stage high-power-factor electronic ballast with symmetrical topology (2003)

This paper proposes a novel single-stage high-power-factor high-efficiency electronic ballast with symmetrical topology for fluorescent lamps. The circuit topology originates from the integration of two half-wave rectifiers with buck-boost power-factor-correction converters and a half-bridge series-resonant parallel-loaded inverter. A high power factor at the input line is assured by operating the buck-boost converters in discontinuous conduction mode. With symmetrical operation and carefully designed circuit parameters, zero-voltage switching on the active power switches of the inverter can be retained to achieve high circuit efficiency. The design equations are derived from the analyzed results based on fundamental approximation, and then an easy-to-use design tool is provided accordingly under considerations of filament heating and ignition. A prototype circuit designed for two T9-40W rapid-start fluorescent lamps is built and tested to verify the analytical predictions. Satisfactory performance is obtained from the experimental results.
ANALYZING THE IMPACT OF TEMPERATURE ON AXOPLASMIC FLUID PROPERTIES DEFINING NEURONAL EXCITATION (2020)

Axoplasmic fluid properties for neuronal excitation have been investigated with respect to temperature. Density, the mass fraction of ions and rate of addition of ions are the parameters considered for characterizing axoplasmic fluid properties. The behavior of these parameters has been analyzed with respect to the changes in temperature ranging from -5 degree Celsius to 35 degree Celsius. The temperature has been defined using Q10of3 coefficient as done in the Hodgkin-Huxley model. The trend of these parameters at different temperatures has been depicted along the axonal length represented through x-axis of the graphs. The conduction velocities of the above said parameters have also been recorded at different temperatures. The range [-5,35] degree Celsius has been increased by 20 degrees, 10 degree on the lower side and 10 degree on the upper side of the range [-5,25] degree Celsius and it is found that temperature dependency using Q10of3 coefficient for said parameters is valid only in the temperature ranging from 5 degree Celsius to 25 degree Celsius as it is for membrane voltage in the Hodgkin-Huxley model. These findings strongly support the obtained results and also suggest obtaining the temperature coefficient value which is applicable for a wider range of temperatures impacting neuronal excitation.
Blog Searching for Competitive Intelligence, Brand Image, and Reputation Management (2005)

Do you know what they are saying about you in the blogosphere? Should you care? Aren't blogs just for kids, political campaigns, and geeks, and of no value in business? If you think that, you're likely missing out on an increasingly powerful information source.\nWhy have blogs, which are simply Web pages with reverse chronologically arranged individual posts, become so powerful? According to David Sifry of Technorati [www.sifry.com/alerts/archives/000298.html], the number of blogs has been doubling at least every five months. The current estimate is that there's over 10 million blogs in the blogosphere. Yet it's not the large number that creates the stir over blogs. Their power comes from the speed of information diffusion, their low barrier to access, and readers' ability to scan many blogs through XML feeds. The vast majority are not journalistic endeavors or political advertising. They are as individual and unique as their writers—and they can damage your company or brand very quickly.
Percutaneous transcatheter laser balloon ablation from the canine coronary sinus: Implications for the Wolff‐Parkinson‐White syndrome (1990)

Transcatheter direct current electrical shocks for ablation of left-sided accessory pathways in Wolff-Parkinson-White patients have led to serious complications. We report the feasibility of percutaneous transcatheter laser balloon ablation of left-sided accessory pathways from the coronary sinus using a 1,064-nm, continuous wave Nd:YAG laser triple lumen catheter with an optical fiber terminating in a cylindrical diffusing tip within a 2-cm-long, 3-mm-diameter balloon transparent to Nd:YAG laser radiation. In eight mongrel dogs (18 to 31 kg), the laser balloon catheter was positioned via an 8 French guide catheter in the distal and proximal coronary sinus. During balloon inflation, two to three consecutive laser doses of 30 W x 20 sec were applied to each site (cumulative energy, 1,200 to 1,800 J). Coronary angiography, left ventriculography, and coronary sinus injection were performed before and after laser exposure. After percutaneous transcatheter laser balloon ablation, there was no evidence of mitral regurgitation, left circumflex artery, coronary sinus obstruction, or perforation. Coagulation necrosis and/or polymorphonuclear infiltrates involving the atrioventricular groove and left atrial wall over a mean length of 17 mm were present in all eight dogs sacrificed 6 +/- 1 hr postablation. In conclusion, percutaneous transcatheter laser balloon ablation from the coronary sinus is free of immediate major complications and may be feasible for potential interruption of left-sided accessory pathways.
Experimental investigation of leaky Lamb modes by an optically induced grating (2002)

By removing the symmetry of a free plate configuration, fluid loading significantly modifies the nature of acoustic waves travelling along a plate, and it even gives existence to new acoustic modes. We present theoretical predictions for the existence, dispersive behavior, and spatial distribution of leaky Lamb waves in a fluid-loaded film. Although Lamb modes are often investigated by studying the radiated fluid waves resulting from their leakage, here their properties are assessed by detecting the wave displacements directly using laser beam deflection. By using crossed laser beam excitation, the detection and analysis of the different modes is done at a fixed wavelength, allowing one to verify the existence, the velocity, and the damping of each predicted mode in a simple and unambiguous way. Our theoretical predictions for the nature of the modes in a water-loaded Plexiglas film, including parts of looping modes, are experimentally confirmed.
Effect of Induction-Hardened Depth on Torsion Fatigue Strength of Notched Specimens (2000)

The effect of induction-hardened depth on torsion fatigue strength of several types of notched specimens were investigated. The results are as follow 1) Induction-hardened specimens show the best torsion fatigue strength when the effective case depth/radius ratio is about 0.5. 2) In the case of shallow case depth, the fatigue cracks initiate at the hardened/non-hardened boundary. On the other hand, the fracture of deeply hardened specimens originates at the surface layer.