gebhart/patrepeval huggingface dataset:
Clinical Experience with MDL 73,745; Pharmacokinetics, Pharmacodynamics, and Clinical Tolerance in Normal Volunteers (1994)

Alzheimer’s disease (AD) represents one of the major debilitating illnesses facing our elderly population today (Jellinger et al., 1990). The magnitude of the financial and social costs associated with this progressive disorder is expected to increase dramatically as the numbers of people reaching their seventies, eighties and nineties continue to grow (Evans et al., 1989). There is clearly a pressing need for new therapies; those which can bring about symptomatic relief, those which can slow down the disease process, and those that can prevent onset of the disease itself. One clinical strategy being explored to relieve symptoms of dementia is to increase levels of the neurotransmitter, acetylcholine (ACh). The scientific rationale is based on the known cholinergic deficit found on post mortem examination (Perry et al., 1978) and clinical observations of improvement using acetylcholinesterase (AChE) inhibitors in the setting of cholinergic deficit (Thal et al., 1989; Davis et al., 1992).
Synthesis of Biodegradable Hybrid Consisting of Hydroxyapatite and Alginate (2005)

Hybrids consisting of hydroxyapatite and biodegradable polymers are attractive materials for bone repair. We recently developed hydroxyapatite-alginate hybrids through a soaking process of alginate modified with 3-aminopropyltriethoxysilane (APES), ethylenediamine (EDA) and CaCl2 in a solution mimicking body fluid such as SBF, 1.5SBF proposed by Kokubo et al.. In this study, biological behavior of the apatite-alginate hybrid fabricated through modification with APES and CaCl2 were evaluated after implantation in a rat tibia, in comparison with that of alginate gel without hydroxyapatite. The higher degree of calcification was observed for the hydroxyapatitealginate hybrid than the alginate gel without hydroxyapatite. The hydroxyapatite precipitated on and inside alginate allowed the hybrid to show not only osteoconduction but also suitable biodegradation after implantation in bony defect.
An Efficient Framework for Animal Breeds Classification Using Semi-Supervised Learning and Multi-Part Convolutional Neural Network (MP-CNN) (2019)

The automatic classification of animal images is an onerous task due to the challenging image conditions, especially when it comes to animal breeds. In this paper, we built a semi-supervised learning based Multi-part Convolutional Neural Network (MP-CNN) that classifies 35,992 animal images from ImageNet into 27 different classes of animals. The proposed model classifies the animals on both generic and fine-grained level. The animal breeds are accurately classified using Multi-part Convolutional Neural Network with a hybrid feature extraction framework of Fisher Vector based Stacked Autoencoder. Furthermore, with Semi-supervised learning based pseudo-labels, the model classifies new classes of unlabeled images too. Modified Hellinger Kernel classifier has been used to re-train the misclassified classes of animals and thereby improve the performance obtained from MP-CNN. The model has experimented with varied tasks to analyze its performance in each of the cases. The experimental results have proved that the coalesced approach of MP-CNN with pseudo-labels can accurately classify animal breeds and we have achieved an accuracy of 99.95% from the proposed model.
THE DYNAMIC TRANSFORMATION OF FERRITE ABOVE AE3 AND THE CONSEQUENCES ON HOT ROLLING OF STEELS (2020)

The occurrence of dynamic transformation of ferrite (DTF) above Ae3 has recently been proven to be an operative mechanism during hot deformation. This work is a preliminary description of the effects of DTF on the thermo-mechanical control processing (TMCP) in hot rolling of steels and a summary TMCP strategies is presented. The occurrence of dynamic transformation of ferrite in the austenite region is proved by means of synchrotron light diffraction methods. This phase transformation mechanism is taken into consideration and its effects on TMCP are proposed.
π-Stacking Induced NMR Spectrum Splitting in Enantiomerically Enriched Ru(II) Complexes:  Evaluation of Enantiomeric Excess (2005)

Several chiral octahedral complexes of the general formula [Ru(bpy)2 (Lig)][PF6]2 (Lig = a ligand that can participate in pi-stacking interactions such as eilatin, isoeilatin, and tpphz) were synthesized in both the racemic and enantiomerically pure/enriched forms. Nonracemic mixtures of enantiomers of all these complexes exhibit splitting of the 1H NMR spectra (NMR nonequivalence); i.e., each spectrum contains a major and a minor set of peaks. The origin of this phenomenon is attributed to a fast equilibrium between monomers and discrete dimers held together by pi-stacking interactions, and it is observed for a wide range of pi-stacking interaction strengths. The NMR spectrum splitting exhibited by these complexes can be exploited for the evaluation of their enantiomeric excess simply from the integral ratio, without addition of chiral shift reagents.
Information integration with attribution support for corporate profiles (1999)

The proliferation of electronically available data within large organizations as well as publicly available data (e.g. over the World Wide Web) poses challenges for users who wish to efficiently interact with and integrate multiple heterogeneous sources. This paper presents CI3, a corporate information integrator, which applies XML as a tool to facilitate data mediation and integration amongst heterogeneous sources in the context of financial analysts creating corporate profiles. Sources include Lotus Notes, relational databases, and the World Wide Web. CI3 applies a unified XML data model to automate integration. By preserving metadata about the source of each datum in the integrated result set, CI3 supports source attribution. Users may trace the attribution metadata from the result back to the underlying sources and leverage their expertise in interpreting the data and, if necessary, use their judgment in assessing the authenticity and veracity of results. We present a functional overview of CI3, its system architecture including the XML data model, and the integration procedures. We conclude by reflecting on lessons learned.
Ion Transport in Isolated Rabbit Ileum (1964)

The addition of actively transported sugars to the solution bathing the mucosal surface of an in vitro preparation of distal rabbit ileum results in a rapid increase in the transmural potential difference, the short-circuit current, and the rate of active Na transport from mucosa to serosa. These effects are dependent upon the active transport of the sugar per se and are independent of the metabolic fate of the transported sugar. Furthermore, they are inhibited both by low concentrations of phlorizin in the mucosal solution and by low concentrations of ouabain in the serosal solution. The increase in the short-circuit current, DeltaI(sc), requires the presence of Na in the perfusion medium and its magnitude is a linear function of the Na concentration. On the other hand, DeltaI(sc) is a saturable function of the mucosal sugar concentration which is consistent with Michaelis-Menten kinetics suggesting that the increase in active Na transport is stoichiometrically related to the rate of active sugar transport. An interpretation of these findings in terms of a hypothetical model for intestinal Na and sugar transport is presented.
An indoor navigation system to support the visually impaired (2008)

Indoor navigation technology is needed to support seamless mobility for the visually impaired. A small portable personal navigation device that provides current position, useful contextual wayfinding information about the indoor environment and directions to a destination would greatly improve access and independence for people with low vision. This paper describes the construction of such a device which utilizes a commercial Ultra-Wideband (UWB) asset tracking system to support real-time location and navigation information. Human trials were conducted to assess the efficacy of the system by comparing target-finding performance between blindfolded subjects using the navigation system for real-time guidance, and blindfolded subjects who only received speech information about their local surrounds but no route guidance information (similar to that available from a long cane or guide dog). A normal vision control condition was also run. The time and distance traveled was measured in each trial and a point-back test was performed after goal completion to assess cognitive map development. Statistically significant differences were observed between the three conditions in time and distance traveled; with the navigation system and the visual condition yielding the best results, and the navigation system dramatically outperforming the non-guided condition.
Explorations in namespace (2006)

DNS cache scanning across a sample set of more than 500,000 name servers revealed the extent of last year's Sony rootkit infestation on client machines.
Synthese et etude de nouveaux reseaux a forte densite de reticulation permeables a l'oxygene : application aux lentilles de contact (1989)

Preparation de reseaux statistiques chioniques par hydrosilylation des doubles liaisons carbone-carbone par des hydrosilanes ou hydrosiloxanes. Analyse des proprietes physiques en relation avec la structure et les teneurs respectives de monomeres (definis en silanes) et des polymeres dans les reseaux. Mesure des coefficients de permeabilite a l'oxygene en milieux aqueux par polarographie
A Facile Synthesis of dl-Sedamine and dl-Allosedamine (1991)

Racemic sedamine and dl-allosedamine were easily syn- thesized £ran the intermediate (3) using a cyclic acyliminium salt by the addition-elimination reaction sequence.Our earlier studieslaflb on the sodium borohydride reduction of succin-and glutarimi-
Practical aspects of sentinel node biopsy in oral cavity cancer: all nodes that emit a signal are important (2021)

SNB has been confirmed to be safe and effective in early stage N0 OCC. However, it is important to carefully harvest up to four hottest SLNs that emit a signal. Treatment of patients with only isolated tumor cells (ITC) in the SLN appears to be necessary.
Analysis of QpRS‐Specific Sequences from Coxiella burnetiia (1990)

Coxiella burnetii from acute cases of Q fever possess a plasmid termed QpH1. Chronic isolates contain a plasmid termed QpRS or have QpRS sequences integrated into the chromosome. The correlation between an isolate's plasmid type and the chronic or acute nature of the disease has prompted analysis of unique plasmid sequences to determine if they contain virulence genes. DNA hybridization has determined that a portion of a 3.6-kb EcoR I fragment (epsilon') is unique to QpRS. In vitro transcription/translation (IVTT) of the epsilon' fragment yielded a 55-kDa protein regardless of the cloning orientation, suggesting that transcription resulted from a rickettsial promoter. A translational start site was mapped to the 1.2-kb Pst I-EcoR I subfragment of epsilon' by IVTT. DNA sequencing showed an open reading frame (ORF) of 1485 bp, capable of coding for a protein of ca. 55.9 kDa. This ORF was termed cbbE'. Putative promoter regions of cbbE' included TTTAAT (-35), TATAAT (-10), and a ribosome-binding site GGAGAGA. The ORF ended with a stop codon UAA and was followed by UAG and a potential factor-independent transcription-termination region. In-frame cloning of the 695-bp Pst I subfragment into pUC9 resulted in a fusion protein of ca. 37 kDa, confirming the frame and length of the ORF as predicted by DNA sequencing. The specificity of this gene to QpRS was confirmed by probing DNA from three plasmid groups of C. burnetii, using the internal 695-bp Pst I fragment of cbbE'.
L-Arginine Derivatives Are Associated with the Hyperthyroid State in the General Population (2015)

The positive associations of ADMA and SDMA with low TSH, fT3, and fT4 argue for a relationship of arginine derivatives with increased thyroid function. This suggests that the atherogenic properties of ADMA and SDMA may be partially mediated by thyroid function.
A Novel Monoclonal Antibody Against the C-terminus of &beta;-Tubulin Recognizes Endocytic Organelles in Trypanosoma cruzi (2012)

Microtubule cytoskeleton is a dynamic structure involved in the maintenance of eukaryote cell shape, motion of cilia and flagellum, and intracellular movement of vesicles and organelles. Many antibodies against tubulins have been described, most of them against the C-terminal portion, which is exposed at the outside of the microtubules. By generating a novel set of monoclonal antibodies against the cytoskeleton of Trypanosoma cruzi, a flagellate protozoan that causes Chagas' disease, we selected a clone (mAb 3G4) that recognizes β-tubulin. The epitope for mAb 3G4 was mapped by pepscan to a highly conserved sequence motif found between α-helices 11 and 12 of the C-terminus of β-tubulin in eukaryotes. It labels vesicular structures in both T. cruzi and mammalian cells, colocalizing respectively with a major cysteine protease (Cruzipain) and lysosome associated protein (LAMP2) respectively, but it does not label regular microtubules on these cellular models. We propose that the epitope recognized by mAb 3G4 is exposed only in a form of tubulin associated with endosomes.
ChemInform Abstract: Mechanistic Studies in the Radical Induced DNA Strand Cleavage — Formation and Reactivity of the Radical Cation Intermediate. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Research on Deep Detection Technology of Abnormal Behavior of Power Industrial Control System (2022)

With the continuous and in-depth development of smart grid construction, the degree of automation of the power system is rapidly increasing, and the number of grid sensors, the scale of information network and the number of decision-making units have greatly increased. The network security of the power industry control system is facing severe challenges. This paper studies the in-depth analysis technology of real-time interactive protocols of power industrial control systems, captures data packets and analyzes the data packets layer by layer to obtain application layer field data streams, and realizes in-depth analysis of power industrial control system protocols such as IEC104 protocol and IEC61850 protocol. Research on anomaly detection technology of power industrial control system real-time interaction process based on feature matching, and realize the detection of abnormal behaviors of terminals, networks, and host devices through syntactic and semantic analysis and business command analysis, as well as the detection of regular network attack behaviors such as malicious code and virus Trojan horses.
Theory of exciton fine structure in semiconductor quantum dots: Quantum dot anisotropy and lateral electric field (2010)

Theory of exciton fine structure in semiconductor quantum dots and its dependence on quantum-dot anisotropy and external lateral electric field is presented. The effective exciton Hamiltonian including long-range electron-hole exchange interaction is derived within the $k\ensuremath{\cdot}p$ effective-mass approximation. The exchange matrix elements of the Hamiltonian are expressed explicitly in terms of electron and hole envelope functions. The matrix element responsible for the ``bright'' exciton splitting is identified and analyzed. An excitonic fine structure for a model quantum dot with quasi-two-dimensional anisotropic harmonic oscillator confining potential is analyzed as a function of the shape anisotropy, size, and applied lateral electric field.
Ferroelectric Columnar Liquid Crystals Realized by Using Rotational Isomerization of a Biphenyl Moiety with Two CF3 Groups (2023)

Ferroelectric columnar liquid crystals have recently been expected to be utilized as high-density memory materials. In this study, we succeeded in realizing ferroelectric columnar liquid crystals by introducing a biphenyl moiety with two CF3 groups in the molecular center. In addition, the introduction enabled the liquid crystal to have a wide temperature range and exhibit an electroresponse at room temperature. This is the first example of ferroelectric columnar liquid crystals realized by using rotational isomerization of a laterally polar biphenyl moiety. Ferroelectric columnar liquid crystals were achieved by introducing a biphenyl moiety with two CF3 groups in the molecular center. In addition, the introduction enabled the liquid crystal to have a wide temperature range and exhibit an electroresponse at room temperature. This is the first example of ferroelectric columnar liquid crystals realized by rotational isomerization of a laterally polar biphenyl moiety.
Online Courses Recommendation based on LDA. (2014)

In this paper we propose a course recommen-dation system based on historical grades of students in college. Our model will be able to recommend available courses in sites such as: Coursera, Udacity, Edx, etc. To do so, proba-bilistic topic models are used as follows. On one hand, Latent Dirichlet Allocation (LDA) topic model infers topics from content given in a college course syllabus. On the other hand, topics are also extracted from a massive online open course (MOOC) syllabus. These two sets of topics and grading information are matched using a content based recommendation system so as to recommend relevant online courses to students. Preliminary results show suitability of our approach. 1
A 4.4mW 76dB complex ΣΔ ADC for Bluetooth receivers (2003)

A /spl Sigma//spl Delta/ ADC with a fifth-order continuous-time complex loop filter achieves 76dB of DNR in a 1MHz channel. The input impedance is less than 400/spl Omega/ and allows operation with a current-mode RF front-end. Image rejection is over 50dB, and IM3 distortion is below -82dBc. The circuit dissipates 4.4mW and is implemented in 0.18/spl mu/m CMOS.
Dynamically discovering and accessing Web services in mobile devices using a load balanced proxy-based server (2013)

Web Service is a collection of open protocols and standards used for exchanging data among different applications or systems. The pervasive nature and advancement in mobile devices has increased the necessity to make web services into certain applications used in such devices. The major requirement for accessing web services dynamically from mobile devices is to improve the processing speed and to save the battery power. This leads to the development of a novel approach to discover and access web services from mobile devices so that user intervention is minimized. It uses search methods for entering the values as parameters to invoke the required service. This paper overcomes the technical challenges in discovering services from mobile devices by means of a proxy server. A Load Balanced proxy server plays an important role in discovering the needed services, downloading the required WSDL file for accessing Web service and using these files to build the proxy class in client side at runtime. This transfers the energy consuming task of mobile device to the proxy server. In addition to these it also overcomes the issues in bandwidth and memory management in invoking the web service. It also performs load balancing on the server to measure its scalability in handling the client requests from mobile device and saving the power in battery for service discovery and invoking process to the server.
Electrical Characteristics of Schottky Contacts on GaN and Al0.11Ga0.89N (2000)

The electrical characteristics of Ag, Ti, Au, Pd and Ni Schottky contacts on GaN and Al 0.11 Ga 0.89 N grown by metalorganic chemical vapour deposition (MOCVD) on sapphire substrates have been investigated. Al 0.11 Ga 0.89 N Schottky barrier height values are bit higher than the values of GaN contacts except Ti Schottky contacts. Fermi-level pinning has been observed for both GaN and Al 0.11 Ga 0.89 N Schottky contacts. The pinning degree of GaN and Al 0.11 Ga 0.89 N are much less than GaAs, Si and GaP, but both of them may be similar to CdS.
An Analytical Model for Loc/ID Mappings Caches (2013)

Concerns regarding the scalability of the inter-domain routing have encouraged researchers to start elaborating a more robust Internet architecture. While consensus on the exact form of the solution is yet to be found, the need for a semantic decoupling of a node's location and identity is generally accepted as a promising way forward. However, this typically requires the use of caches that store temporal bindings between the two namespaces, to avoid hampering router packet forwarding speeds. In this article, we propose a methodology for an analytical analysis of cache performance that relies on the working-set theory. We first identify the conditions that network traffic must comply with for the theory to be applicable and then develop a model that predicts average cache miss rates relying on easily measurable traffic parameters. We validate the result by emulation, using real packet traces collected at the egress points of a campus and an academic network. To prove its versatility, we extend the model to consider cache polluting user traffic and observe that simple, low intensity attacks drastically reduce performance, whereby manufacturers should either overprovision router memory or implement more complex cache eviction policies.
Adaptive Robust Output-Feedback Motion/Force Control of Electrically Driven Nonholonomic Mobile Manipulators (2008)

In this brief, adaptive robust output-feedback force/motion control strategies are presented for mobile manipulators under both holonomic and nonholonomic constraints in the presence of uncertainties and disturbances. The controls are developed on structural knowledge of the dynamics of the robot and actuators and in conjunction with a linear observer. The proposed controls are robust not only to parametric uncertainty such as mass variations but also to external ones such as disturbances. The system stability and the boundedness of tracking and observation errors are proven using Lyapunov stability synthesis. Simulation results validate that the states of the system converge to the desired trajectory, while the constraint force converges to the desired force.
A Taxonomy for Three-Terminal Tandem Solar Cells (2020)

Tandem and multijunction solar cells offer the only demonstrated path to terrestrial 1-sun solar cell efficiency over 30%. Three-terminal tandem (3TT) solar cells can overcome some of the limitations of two-terminal and four-terminal tandem solar cell designs. However, the coupled nature of the cells adds a degree of complexity to the devices themselves and the ways that their performance can be measured and reported. While many different configurations of 3TT devices have been proposed, there is no standard taxonomy to discuss the device structure or loading topology. This Perspective proposes a taxonomy for 3TT solar cells to enable a common nomenclature for discussing these devices and their performance. It also provides a brief history of three-terminal devices in the literature and demonstrates that many different 3TT devices can work at efficiencies above 30% if properly designed.
Anomaly detection in reconstructed quantum states using a machine-learning technique (2014)

The accurate detection of small deviations in given density matrices is important for quantum information processing. Here we propose a method based on the concept of data mining. We demonstrate that the proposed method can more accurately detect small erroneous deviations in reconstructed density matrices, which contain intrinsic fluctuations due to the limited number of samples, than a naive method of checking the trace distance from the average of the given density matrices. This method has the potential to be a key tool in broad areas of physics where the detection of small deviations of quantum states reconstructed using a limited number of samples is essential.