gebhart/patrepeval huggingface dataset:
Molecular Cloning of the Rat Intestinal Trefoil Factor Gene (1995)

Intestinal trefoil factor (ITF) is a small peptide bearing the unique motif of intrachain disulfide bonds characteristic of the trefoil family. Previous work had localized expression of ITF primarily within goblet cells in the small and large bowel, making it a candidate gene for the study of the molecular basis of intestinal and goblet cell-specific gene expression. In order to study the regulation of ITF expression, we have cloned the rat ITF gene and sequenced 1.7 kilobases of the 5'-flanking region. RNase protection analysis demonstrated a single transcriptional start site. Various lengths of the 5'-flanking region were linked to the reporter gene luciferase and transfected into the colon cancer cell lines LS174T and Caco-2, representing, respectively, cells with and without goblet cell-like phenotype. Expression in the goblet cell-like LS174T colon cancer cell line was nearly 10-fold greater than expression in Caco-2 cells which exhibit columnar enterocyte-like phenotype. The pattern of goblet cell-associated selective transcription required only 153 base pairs of the rat ITF 5'-flanking sequence. Transfection of a construct of human growth hormone under the control of the rat ITF promoter in the N2 subclone of HT-29 cells demonstrated expression of the reporter gene only in those cells exhibiting a goblet cell phenotype as assessed by expression of immunoreactive mucin. These initial studies of the 5'-flanking region of the ITF gene demonstrate the presence of cis-regulatory elements capable of directing goblet cell specific expression.
Interaction of C5 protein with RNA aptamers selected by SELEX (2002)

RNA aptamers binding to C5 protein, the protein component of Escherichia coli RNase P, were selected and characterized as an initial step in elucidating the mechanism of action of C5 protein as an RNA-binding protein. Sequence analyses of the RNA aptamers suggest that C5 protein binds various RNA molecules with dissociation constants comparable to that of M1 RNA, the RNA component of RNase P. The dominant sequence, W2, was chosen for further study. Interactions between W2 and C5 protein were independent of Mg2+, in contrast to the Mg2+ dependency of M1 RNA-C5 protein interactions. The affinity of W2 for C5 protein increased with increasing concentration of monovalent NH4+, suggesting interactions via hydrophobic attraction. W2 forms a fairly stable complex with C5 protein, although the stability of this complex is lower than that of the complex of M1 RNA with C5 protein. The core RNA motif essential for interaction with C5 protein was identified as a stem-loop structure, comprising a 5 bp stem and a 20 nt loop. Our results strongly imply that C5 protein is an interacting partner protein of some cellular RNA species apart from M1 RNA.
Ultrafast oxygen exchange kinetics on highly epitaxial PrBaCo2O5+δ thin films (2012)

Symmetric half cell structures of highly epitaxial PrBaCo2O5+δ (PBCO)/Gd0.8Ce0.2.2O2:Y0.08Zr0.92O2/PrBaCo2O5+δ thin films were designed and fabricated on (001) LaAlO3. Microstructural studies indicate that the multilayer films have excellent single-crystal quality and epitaxial nature. The electrochemical impedance spectroscopy measurements reveal that the PBCO film electrodes have a polarization resistance as low as 0.109 Ω cm2 at 597 °C in air and an ultrafast surface exchange coefficient (0.006 cm/s at 598 °C) with low activation energy (0.77 eV). The low polarization resistance and rapid surface oxygen exchange kinetics suggest that the PBCO can be an excellent cathode material for intermediate-temperature solid oxide fuel cells.
Emulsion Science and Technology (2009)

EMULSION SCIENCE AND TECHNOLOGY: A GENERAL INTRODUCTION Introduction Industrial Applications of Emulsions The Physical Chemistry of Emulsion Systems The Thermodynamics of Emulsion Formation and Breakdown Interaction Energies (Forces) Between Emulsion Droplets and Their Combinations Adsorption of Surfactants at the Liquid/Liquid Interface Selection of Emulsifiers Creaming or Sedimentation of Emulsions Flocculation of Emulsions Ostwald Ripening Emulsion Coalescence Rheology of Emulsions STABILIZATION OF EMULSIONS, NANOEMULSIONS AND MULTIPLE EMULSIONS USING HYDROPHOBICALLY MODIFIED INULIN (POLYFRUCTOSE) Introduction Experimental Results and Discussion INTERACTION FORCES IN EMULSION FILMS STABILIZED WITH HYDROPHOBICALLY MODIFIED INULIN (POLYFRUCTOSE) AND CORRELATION WITH EMULSION Introduction Materials and Methods Results and Discussion ENHANCEMENT OF STABILIZATION AND PERFORMANCE OF PERSONAL CARE FORMULATIONS USING POLYMERIC SURFACTANTS Introduction Experimental Results and Discussion EFFECT OF AN EXTERNAL FORCE FIELD ON SELF-ORDERING OF THREE-PHASE CELLULAR FLUIDS IN TWO DIMENSIONS Introduction The Model Results and Discussion THE PHYSICAL CHEMISTRY AND SENSORY PROPERTIES OF COSMETIC EMULSIONS: APPLICATIONS TO FACE MAKE-UP FOUNDATIONS Introduction Materials and Methods Experimental Results and Discussion NANOPARTICLE PREPARATION BY MINIEMULSION POLYMERIZATION Introduction Experimental Results and Discussion RECENT DEVELOPMENTS IN PRODUCING MONODISPERSE EMULSIONS USING STRAIGHT-THROUGH MICROCHANNEL ARRAY DEVICES Introduction Principles of Microchannel Emulsification Straight-Through MC Array Device and Emulsification Set-Up Effect of Channel Shapes on Emulsification Using Symmetric Straight-Through MC Arrays Effect of Process Factors on Emulsification Using Symmetric Straight-Through MC Arrays Scaling-Up of Straight-Through MC Array Devices Emulsification Using an Asymmetric Straight-Through MC Array ISOTROPIC AND ANISOTROPIC METAL NANOPARTICLES PREPARED BY INVERSE MICROEMULSIONS Introduction General Aspects of Microemulsions Isotropic Nanoparticles Anisotropic Nanoparticles PREPARATION OF NANOEMULSIONS BY SPONTANEOUS EMULSIFICATION AND STABILIZATION WITH POLY(CAPROLACTONE)-b-POLY(ETHYLENE OXIDE) BLOCK COPOLYMERS Introduction Materials and Methods Results and Discussion ROUTES TOWARDS THE SYNTHESIS OF WATERBORNE ACRYLIC/CLAY NANOCOMPOSITES Introduction Experimental Results and Discussion PREPARATION CHARACTERISTICS OF GIANT VESICLES WITH CONTROLLED SIZE AND HIGH ENTRAPMENT EFFICIENCY USING MONODISPERSE WATER-IN-OIL EMULSIONS Introduction Materials and Methods Results and Discussion ON THE PREPARATION OF POLYMER LATEXES (CO)STABILIZED BY CLAYS Introduction Cloisite Clays and Organoclays Radical Polymerization Collective Properties of Polymer/MMT Nanocomposites Polymer-Inorganic Nanocomposites General
Caloric Needs of Adolescent Patients with Burns (1989)

Formulas for estimating the caloric requirements of pediatric and adult patients with burns have been suggested. However, the needs of adolescent patients with burns have not been specifically addressed. This study was undertaken to determine the calorie intake required to maintain weight of adolescent patients with burns over more than 35% of the total body surface area. The 29 patients studied were divided into two groups according to sex. Caloric requirements were determined with the use of the Galveston surface area formula and the Curreri formula. The comparison of these estimations with the actual intake required to maintain weight indicated that there is a significant difference between the calories indicated by the formulas and the actual intake. A surface area formula that also correlates with the results of indirect-calorimetry studies is suggested for this adolescent population with burns.
Effekt von strukturierten Evaluationen auf den Unterricht praktischer Fertigkeiten im Fach Chirurgie (2014)

Fragestellung/Einleitung: Evaluationen sind ein wichtiges Instrument um Lehrveranstaltungen zu bewerten und zu verbessern. Im Rahmen des Blockpraktikums Chirurgie durchlaufen die Studierenden ein „Training praktischer Fertigkeiten“. Hierbei erlernen sie in 12 Modulen im Skills-Lab[for full text, please go to the a.m. URL]
Abstract 12065: Optimal Projections for the Angiographic Imaging and the Percutaneous Closure of the Left Atrial Appendag:. Lessons Learned From the Intraprocedural Reconstruction of the Left Atrium and the Pulmonary Veins (2011)

Introduction: Percutaneous left atrium appendage (LAA) obliteration is a new alternative strategy for prevention of embolic events in patients with atrial fibrillation (AF) and contraindications to...
Isothiazoles. Part XIV. 5-Alkoxy- and 5-hydroxyisothiazoles (1971)

5-Bromoisothiazoles are attacked by nucleophiles to give 5-alkoxy- and (the hitherto unknown) 5-hydroxy-iso-thiazoles. 4-Bromo-5-hydroxy-3-methylisothiazole has been prepared by hydrolytic decomposition of the appropriate 5-diazonium fluoroborate. Preliminary studies on the tautomeric state of the hydroxyisothiazoles are reported.
Inborn errors in RNA polymerase III underlie severe varicella zoster virus infections (2017)

Varicella zoster virus (VZV) typically causes chickenpox upon primary infection. In rare cases, VZV can give rise to life-threatening disease in otherwise healthy people, but the immunological basis for this remains unexplained. We report 4 cases of acute severe VZV infection affecting the central nervous system or the lungs in unrelated, otherwise healthy children who are heterozygous for rare missense mutations in POLR3A (one patient), POLR3C (one patient), or both (two patients). POLR3A and POLR3C encode subunits of RNA polymerase III. Leukocytes from all 4 patients tested exhibited poor IFN induction in response to synthetic or VZV-derived DNA. Moreover, leukocytes from 3 of the patients displayed defective IFN production upon VZV infection and reduced control of VZV replication. These phenotypes were rescued by transduction with relevant WT alleles. This work demonstrates that monogenic or digenic POLR3A and POLR3C deficiencies confer increased susceptibility to severe VZV disease in otherwise healthy children, providing evidence for an essential role of a DNA sensor in human immunity.
Molecular interactions in mixtures of carboxylic acids with amines. 1. Melting curves and viscosities (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMolecular interactions in mixtures of carboxylic acids with amines. 1. Melting curves and viscositiesFriedrich Kohler, H. Atrops, H. Kalali, E. Liebermann, Emmerich Wilhelm, F. Ratkovics, and T. SalamonCite this: J. Phys. Chem. 1981, 85, 17, 2520–2524Publication Date (Print):August 1, 1981Publication History Published online1 May 2002Published inissue 1 August 1981https://pubs.acs.org/doi/10.1021/j150617a021https://doi.org/10.1021/j150617a021research-articleACS PublicationsRequest reuse permissionsArticle Views882Altmetric-Citations114LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
The progress made using the combustion chemical vapor deposition (CCVD) technique to fabricate YBa/sub 2/Cu/sub 3/O/sub 7-X/ coated conductors (2003)

Combustion Chemical Vapor Deposition (CCVD) is a nonvacuum technique being investigated, in conjunction with the Rolling Assisted Biaxially Textured Substrates (RABiTS/spl trade/) process, as a method to fabricate low-cost, long-length Yttrium Barium Copper Oxide (YBCO) coated conductor tapes. This technique has been scaled to produce meter + lengths of buffer material with excellent epitaxial and microstructural uniformity along the length. Additional efforts focus on depositing YBCO on these lengths using several deposition techniques including CCVD. Pulsed laser deposition (PLD) YBCO with critical current densities >1 MA/cm/sup 2/ have been achieved on short coupons taken from meter lengths of CeO/sub 2//STO/Ni architectures. CCVD buffer layers on Ni-W are still being optimized as YBCO critical current densities are less than 50,000 A/cm/sup 2/. The critical current densities of coupons of YBCO deposited by CCVD onto CCVD buffered substrates is increasing up to 100,000 A/cm/sup 2/, but further optimization is needed to yield high performance samples.
Method for Compensation of Eye Movements in Adaptive Optics (2010)

Method for Compensation of Eye Movements in Adaptive OpticsThe benefit of correction of aberrations in the human eye with adaptive optics is strongly reduced by eye movements. Although devices for compensation of eye movements have already been developed, these are very advanced and expensive. We are working on the development of a novel method for eye movement compensation based on the detection of a corneal reflex by a linear profile sensor. Electronic circuits for controlling the profile sensor and stepper motors have already been designed. Next, a circuit must be designed so that the profile sensor controls the stepper motor. One of the shortcomings of this method is that a stepper motor runs at low speed. Another shortcoming is that the profile sensor operates in only one dimension. However, these problems can be solved by using a two-dimensional profile sensor and piezo-mounts working at much higher frequencies.
Stochastic constraints for efficient image correspondence search (2006)

The navigation state (position, velocity, and attitude) can be determined using optical measurements from an imaging sensor pointed toward the ground. Extracting navigation information from an image sequence depends on tracking the location of stationary objects in multiple images, which is generally termed the correspondence problem. This is an active area of research and many algorithms exist which attempt to solve this problem by identifying a unique feature in one image and then searching subsequent images for a feature match. In general, the correspondence problem is plagued by feature ambiguity, temporal feature changes, and occlusions which are difficult for a computer to address. Constraining the correspondence search to a subset of the image plane has the dual advantage of increasing robustness by limiting false matches and improving search speed. A number of ad hoc methods to constrain the correspondence search have been proposed in the literature. A rigorous stochastic projection method is developed here which constrains the correspondence search space by incorporating a priori knowledge of the aircraft navigation state using inertial measurements and a statistical terrain model. The stochastic projection algorithm is verified using Monte Carlo simulation and flight data. The constrained correspondence search area is shown to accurately predict the pixel location of a feature with an arbitrary level of confidence, thus promising improved speed and robustness of conventional algorithms
Properties of solution. Water research program biennial progress report, March 15, 1966--March 15, 1968 (1973)

between the Department of thE:. I1:1terior and the }\tomic,.Ene_rgy Coi!Wlispion.
Quality Evaluation of 3D Objects in Mixed Reality For Different Lighting Conditions (2020)

This paper presents a study on Quality of Experience (QoE) evaluation of 3D objects in Mixed Reality (MR) scenarios. In particular, a subjective test was performed with Microsoft HoloLens, considering different degradations affecting the geometry and texture of the content. Apart from the analysis of the perceptual effects of these artifacts, given the need for recommendations for subjective assessment of immersive media, this study was also aimed at: 1) checking the appropriateness of a single stimulus methodology (ACR-HR) for these scenarios where observers have less references than with traditional media, and 2) analyzing the possible impact of environment lighting conditions on the quality evaluation of 3D objects in mixed reality (MR), and 3) benchmark state-of-the-art objective metrics in this context. The subjective results provide insights for recommendations for subjective testing in MR/AR, showing that ACR-HR can be used in similar QoE tests and reflecting the influence among the lighting conditions, the content characteristics, and the type of degradations. The objective results show an acceptable performance of perceptual metrics for geometry quantization artifacts and point out the need of further research on metrics covering both geometry and texture compression degradations.
MIMO Coded Generalized Reduced Dimension Fourier Algorithm for 3-D Microwave Imaging (2023)

In this paper, to accelerate data acquisition and image reconstruction procedures in a multistatic short-range microwave imaging scenario, an orthogonal coding approach with Fourier domain processing is presented. First, a special two-dimensional (2D) multiple-input multiple-output (MIMO) structure is introduced to fully electronically synthesize the 2D aperture. Then, the model of the transmitted and received signals by a MIMO stepped-frequency-modulated radar is presented, with special considerations about orthogonal, balanced and optimal sequences. On the receiver side, the backscatter frequency response extraction process is formulated with the aim of obtaining individual information of all channels. Finally, based on the introduced model, a fast Fourier-based algorithm with reduced dimensions, named MIMO coded generalized reduced dimension Fourier (CGRDF), is mathematically derived. It includes extracting phase and amplitude compensators with the aim of mapping 4D to 2D spatial data, transferring the backscatter transfer function from the spatial domain to the wavenumber domain, extracting the smoothing filter, compensating the curvature of the wavefront of all scatterers, extracting the reflectivity function and an additional range compensator. The results of numerical simulations show the satisfactory and reliable performance of the proposed approach in terms of the information retrieval process and processing speed.
Comparison of DX-8951f and topotecan effects on tumor colony formation from freshly explanted adult and pediatric human tumor cells (1999)

DX-8951f, which shows great therapeutic potential, was tested in the human tumor cloning system in adult and pediatric tumor types against which topotecan has been active. In 47 tumors from adults, DX-8951f had definite cytotoxic activity in a concentration-dependent manner with both 1 h and continuous exposures. Topotecan was minimally effective using a 1 h exposure and showed concentration-dependent inhibition with continuous exposure. In head-to-head comparisons at 1 h exposure against adult tumors, DX-8951f was significantly more effective at 0.1 and 1.0 microg/ml than topotecan. In head-to-head comparisons (continuous exposure), 1.0 microg/ml DX-8951f was more effective than topotecan at 1.0 microg/ml in adult tumors, including three of four head and neck, one of two kidney, two of five liver, six of 10 non-small cell lung, five of eight ovarian, four of eight prostate tumors, and in single specimens of breast, mesothelioma, colon and small cell lung tumors. With continuous exposure, DX-8951f and topotecan were equally effective at equimolar concentrations. The maximum tolerated dose for DX-8951f is 3 times that of topotecan, so higher doses of DX-8951f could be administered to patients. DX-8951f is a promising new antineoplastic agent with significant activity against tumors taken directly from patients.
Gunshot Injuries in the Elderly: Patterns and Outcomes. A National Trauma Databank Analysis (2011)

Injury from firearms is not uncommon in the elderly patient population and is primarily a result of self-inflicted gunshot wounds to the head. These patients sustain a high burden of injury and a high rate of mortality, which increases with advancing age.
Ozonolysis of 2′-Deoxycytidine: Isolation and Identification of the Main Oxidation Products (1997)

The ozone-mediated oxidation of 2′-deoxycytidine (dCyd) was investigated on the basis of final product identification. The oxidation reaction gave rise to five major modified nucleosides which were isolated and characterized on the basis of extensive 1H NMR and mass spectrometry measurements. The comparison with the current knowledge of the hydroxyl radical mediated oxidation reactions of 2′-deoxycytidine in aerated aqueous solution, indicates that the formation of ozone oxidation products may be mostly explained by the opening of the pyrimidine C5-C6 double bond. Thus, the formation of the identified products obtained by ozonolysis of 2′-deoxycytidine is accounted for by the initial generation of an ozonide.
Dispatch Model of Combined Heat and Power Plant Considering Heat Transfer Process (2017)

Due to the coupling of its heat and power output, combined heat and power (CHP) has limited flexibility, which is one of the main reasons for variable renewable energy source (RES) curtailment problem in Northern China. Almost all the existing studies have modelled the CHP's output characteristics as a feasible operation region of electric power and heat power. However, only the extraction steam of a CHP unit that used for district heating can be controlled directly, without considering the extraction steam's heat transfer process, the actual heat power output cannot be precisely decided. Thus this paper proposes a detailed CHP dispatch model based on the principles of heat transfer. A three-stage heat transfer model of the extraction steam is used to describe the heating process. Then, a joint dispatch model concerning CHP units, conventional thermal power units, and RESs is given. Finally, the impacts of different factors on the extraction steam's heat transfer process and its influence for RES accommodation are analyzed. Results show that considering heat transfer process is essential in modelling the CHP plant that used for district heating, especially when the CHP plant is working at a status that deviates from the rated one significantly.
Properties of Polyhexamethylene Guanidine (PHMG) Associated with Fatal Lung Injury in Korea (2020)

The use of humidifier disinfectant (HD) has been determined to be associated with lung injuries (HDLI) in Korea. Although HD brands containing polyhexamethylene guanidine (PHMG) oligomers have been found to cause more HDLI compared to brands containing other disinfectants, the physicochemical properties of PHMG have been poorly defined. We aimed to quantify the PHMG dissolved in HD brands, characterize the number-average (<i>M<sub>n</sub></i>) and weight-average (<i>M<sub>w</sub></i>) molecular masses, and identify the polymerization degree of PHMG. Analysis of the PHMG oligomers was performed using a matrix-assisted laser desorption/ionization time-of-flight mass spectrometer (MALDI-TOF MS) operated in positive-ion reflectron mode. Eight brands of HD containing PHMG were identified. The PHMG concentrations in these brands ranged from 160 to 37,200 ppm (mean = 3100.9 ppm). Concentration was a significant variable among and within HD brands. The degree of PHMG oligomerization fell within the range of two to four. The averages of <i>M<sub>n</sub></i> and <i>M<sub>w</sub></i> were 517.2 g/mol (range: 422-613 g/mol) and 537.3 g/mol (range: 441.0-678.0 g/mol), respectively. Based on the average molecular weight and the degree of polymerization, the PHMG examined here could be regarded as oligomers, which may be associated with the highest proportion of HDLI being caused by PHMG.