gebhart/patrepeval huggingface dataset:
Development and Validation of a New Clinical Scale for Infants with Acute Respiratory Infection: The ReSVinet Scale (2016)

The ReSVinet scale may be useful and reliable in the evaluation of infants with ARI, particularly acute bronchiolitis, even with data obtained from medical records and when employed by parents. Although further studies are necessary, ReSVinet scale already complies with more score validation criteria than the vast majority of the alternatives currently available and used in the clinical practice.
Pterostilbene and Its Glucoside Induce Type XVII Collagen Expression (2017)

The glycosylation of pterostilbene by cultured plant cells of Phytolacca americana gave pterostilbene 4'-O-β-D-glucoside. Both pterostilbene and its 4'-0-β-D- glucoside induced type XVII collagen expression in the EpiDermFT EFT-400 human skin cell model. Pterostilbene 4'-O-β-D-glucoside strongly induced type XVII collagen expression rather than pterostilbene.
Advanced membrane science and technology for sustainable energy and environmental applications (2011)

Membrane materials allow for the selective separation of gas and vapour and for ion transport. Materials research and development continues to drive improvements in the design, manufacture and integration of membrane technologies as critical components in both sustainable energy and clean industry applications. Membrane utilisation offers process simplification and intensification in industry, providing low-cost, and efficient and reliable operation, and contributing towards emissions reductions and energy security. Advanced membrane science and technology for sustainable energy and environmental applications presents a comprehensive review of membrane utilisation and integration within energy and environmental industries. Part one introduces the topic of membrane science and engineering, from the fundamentals of membrane processes and separation to membrane characterization and economic analysis. Part two focuses on membrane utilisation for carbon dioxide (CO2) capture in coal and gas power plants, including pre- and post-combustion and oxygen transport technologies. Part three reviews membranes for the petrochemical industry, with chapters covering hydrocarbon fuel, natural gas and synthesis gas processing, as well as advanced biofuels production. Part four covers membranes for alternative energy applications and energy storage, such as membrane technology for redox and lithium batteries, fuel cells and hydrogen production. Finally, part five discusses membranes utilisation in industrial and environmental applications, including microfiltration, ultrafiltration, and forward osmosis, as well as water, wastewater and nuclear power applications. © 2011 Woodhead Publishing Limited. All rights reserved.
Isolation and Generation of Clinical-Grade Dendritic Cells Using the CliniMACS System (2004)

Dendritic cells (DC) can either be generated from progenitors such as stem cells or CD14+ monocytes, or isolated directly from the blood. Blood-derived DC are present as at least two distinct populations-myeloid and plasmacytoid DC. Here we describe methods for the clinical-grade isolation of blood DC and DC precursors using the CliniMACS. We describe the isolation of ultra-pure monocytes in order to generate large numbers of monocyte-derived DC, and also new methods for the direct isolation of blood DC. Isolation of blood DC in large numbers means that natural DC with different properties can be investigated for their clinical function for the first time.
Ninety-day administration of dl-3-n-butylphthalide for acute ischemic stroke: a randomized, double-blind trial (2013)

The 90-day treatment with NBP could improve outcomes at the third month after stroke. The NBP treatment (both intravenous and oral) is safe (ChiCTR-TRC-09000483).
Investigation on Co–Modified Ni x Mg y O Solid Solutions for Hydrogen Production from Steam Reforming of Acetic Acid and a Model Blend (2019)

Abstract This paper is focused on the Co‐modified Ni x Mg y O solid solutions (10 wt% Ni, 2–6 wt% Co) for the steam reforming of acetic acid and a model blend. The pristine rocksalt structured Ni x Mg y O solid solution and the modified Ni x Mg y O−Co catalysts were synthesized via hydrothermal method and co‐impregnation. The activity of the catalysts was evaluated in the temperature range of 500–800 °C with a steam/carbon molar ratio of 3 and a gas hourly space velocity ( GHSV ) of 57,000 h −1 . Low cobalt content (Co loading 2 wt%) catalysts exhibited significant promotion of H 2 yield via enhancement of both water‐gas shift (WGS) reaction and methane decomposition. A 30‐hour test at 700 °C achieved excellent acetic acid conversion rate and H 2 yield of 99.1% and 86.9%, respectively. However, the catalysts with higher cobalt loading (Co loading 4 wt%) suffered a much quicker deactivation mainly due to carbon deposition. In addition, the catalysts were also tested on a model blend combined acids, alcohols and aromatic species and exhibited outstanding performance with carbon conversion above 90% and H 2 yield above 70% for 100 h.
A Supplier Performance Evaluation Solution for Proactive Supplier Quality Management (2008)

Todaypsilas business environment forces companies to rely heavily on suppliers for products, services, and software. The increased reliance on suppliers and the growing complexity of the products, services and extended supply chain raises the importance of having an effective supplier quality management system. One of the keys to an effective supplier quality management system is the ability to provide an end to end supplier performance evaluation system.In this paper, we present a Supplier Performance Evaluation (SPE) solution which has been developed and commercialized that provides effective decision support for sourcing and supplier improvement. More specifically, this solution provides a real-time evaluation of supplier performance by consolidating information across functions, organizations, and various product lines throughout the product lifecycle. Its scoring function combines both subjective and objective metrics using data from surveys, engineering, manufacturing quality, warranty claims and other sources. An embedded alert management function helps to raise the timely awareness of quality issues related to suppliers, or supplied parts. Finally, a supplier performance evaluation example process is illustrated to showcase the usage of the solution.
730 (2012)

Introduction: Approximately 40% of patients admitted to critical care units require mechanical ventilation (MV). Volume status and cardiac function have been considered important predictors of weaning among patients in the ICU but have not been studied among patients on prolonged MV. This study was conducted to study the role of volume status and cardiac function (as assessed via echocardiography) as predictors in this population. Hypothesis: Volume status and cardiac function assessed via echocardiogram predict weaning outcomes among patients on prolonged MV. Methods: We conducted a retrospective chart review of all adult patients on prolonged MV admitted to the Respiratory Special Care Unit (ReSCU, a long term weaning unit) at the Cleveland Clinic Hospital from April 2011 through May 2012. Prolonged MV was defined as need for MV for at least 6 hours daily for at least 21 consecutive days. Liberation from MV within 24 hours of admission to the unit and unavailability of echocardiogram in 2 weeks prior to admission or at admission were grounds for exclusion (n=66, mean age 60.8 years, M:F 33:33).Demographic, clinical and laboratory variables on day of admission were recorded. Echocardiogram done at the time of admission to the unit or within the last 2 weeks was reviewed and variables reflective of volume status (such as left atrium size, IVC collapsibility) and right and left ventricular function were recorded. Successful weaning, defined as breathing independent of MV for? 72 consecutive hours, was the primary endpoint. Variables were compared between patients who were weaned versus those who could not be weaned. Results: Caucasians formed the majority of the study group (n=53, 80.3%) followed by African Americans (n=10, 15.2%) Pneumonia was the most common etiology for respiratory failure. 37 patients (56.1%) patients were successfully weaned. Weaned patients were younger (mean age 55 ± 18 vs 68 ± 12 years, p=0.001) and had better nutritional status (mean albumin levels 2.73 ± 0.44 vs 2.42 ± 0.41 g/dL, p=0.005). None of the echocardiographic parameters predicted successful weaning (weaned vs not weaned respectively: left ventricular ejection fraction 56.1 ± 7.6% vs 52.4 ± 10.5%; left atrial enlargement among 40% vs 50%; mean right ventricular systolic pressure 42.3 ± 19.9 vs 41.8 ± 15.2 mm Hg; presence of right ventricular systolic dysfunction among 51.4% vs 41.7%; right ventricular dilatation 45.7% vs 36%; right atrial enlargement 19.4% vs 22.2%; mean inferior vena cava diameter 2.1 ± 0.5 cm vs 2.1 ± 0.4 cm; all P=NS). Conclusions: Most patients requiring prolonged MV can be successfully weaned. Whereas younger age and better nutritional status at baseline favors successful wean, volume status and cardiac function assessed via echocardiogram do not help to prognosticate these patients.
Anytime Motion Planning using the RRT* (2011)

The Rapidly-exploring Random Tree (RRT) algorithm, based on incremental sampling, efficiently computes motion plans. Although the RRT algorithm quickly produces candidate feasible solutions, it tends to converge to a solution that is far from optimal. Practical applications favor "anytime" algorithms that quickly identify an initial feasible plan, then, given more computation time available during plan execution, improve the plan toward an optimal solution. This paper describes an anytime algorithm based on the RRT* which (like the RRT) finds an initial feasible solution quickly, but (unlike the RRT) almost surely converges to an optimal solution. We present two key extensions to the RRT% committed trajectories and branch-and-bound tree adaptation, that together enable the algorithm to make more efficient use of computation time online, resulting in an anytime algorithm for real-time implementation. We evaluate the method using a series of Monte Carlo runs in a high-fidelity simulation environment, and compare the operation of the RRT and RRT* methods. We also demonstrate experimental results for an outdoor wheeled robotic vehicle.
Modeling of Stimulation Intensity and Swallowing using the Swallowing Sounds (2014)

嚥下感覚は ｢食｣ を楽しむ要素の1つと考えられているが, 嚥下感覚は主観的要素が強く, 工学的検証は不十分であった. そこで, 本研究では嚥下音や筋活動計測から嚥下活動と嚥下感覚の関係をモデル化することを目的とした. 本稿では, 嚥下試料として炭酸水を用い, 炭酸強度を変化させながら, 嚥下中の嚥下音および筋電を計測することで, 炭酸強度と嚥下活動の関係を解析した. その結果, 炭酸強度によって, 嚥下音ハイパワー部面積, 嚥下音発生時間と筋電の活動時間に統計的有意差が確認された. さらに, 刺激強度, 嚥下方法, 嚥下感覚のモデル化を行い, 炭酸強度に対して嚥下感覚は上に凸の特性を持つことが示唆された.
Copper-Mediated Cross-Coupling of Organostannanes with Organic Iodides at or below Room Temperature (1996)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTCopper-Mediated Cross-Coupling of Organostannanes with Organic Iodides at or below Room TemperatureGary D. Allred and Lanny S. LiebeskindView Author Information Sanford S. Atwood Chemistry Center, Emory University 1515 Pierce Drive, Atlanta, Georgia 30322 Cite this: J. Am. Chem. Soc. 1996, 118, 11, 2748–2749Publication Date (Web):March 20, 1996Publication History Received7 December 1995Published online20 March 1996Published inissue 1 January 1996https://pubs.acs.org/doi/10.1021/ja9541239https://doi.org/10.1021/ja9541239rapid-communicationACS PublicationsCopyright © 1996 American Chemical SocietyRequest reuse permissionsArticle Views10904Altmetric-Citations428LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information SUBJECTS:Anions,Copper,Cross coupling reaction,Salts,Transmetalation Get e-Alerts
Contribution of Entanglements to the Equilibrium Modulus of 1,2-Polybutadiene Networks at Small Strains and Estimate of the Front Factor (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTContribution of Entanglements to the Equilibrium Modulus of 1,2-Polybutadiene Networks at Small Strains and Estimate of the Front FactorS Hvidt, O Kramer, W Batsberg, and J FerryCite this: Macromolecules 1980, 13, 4, 933–939Publication Date (Print):July 1, 1980Publication History Published online1 May 2002Published inissue 1 July 1980https://doi.org/10.1021/ma60076a032RIGHTS & PERMISSIONSArticle Views103Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (854 KB) Get e-Alerts Get e-Alerts
A new l‐arginine oxidase engineered from l‐glutamate oxidase (2021)

The alternation of substrate specificity expands the application range of enzymes in industrial, medical, and pharmaceutical fields. l-Glutamate oxidase (LGOX) from Streptomyces sp. X-119-6 catalyzes the oxidative deamination of l-glutamate to produce 2-ketoglutarate with ammonia and hydrogen peroxide. LGOX shows strict substrate specificity for l-glutamate. Previous studies on LGOX revealed that Arg305 in its active site recognizes the side chain of l-glutamate, and replacement of Arg305 by other amino acids drastically changes the substrate specificity of LGOX. Here we demonstrate that the R305E mutant variant of LGOX exhibits strict specificity for l-arginine. The oxidative deamination activity of LGOX to l-arginine is higher than that of l-arginine oxidase form from Pseudomonas sp. TPU 7192. X-ray crystal structure analysis revealed that the guanidino group of l-arginine is recognized not only by Glu305 but also Asp433, Trp564, and Glu617, which interact with Arg305 in wild-type LGOX. Multiple interactions by these residues provide strict specificity and high activity of LGOX R305E toward l-arginine. LGOX R305E is a thermostable and pH stable enzyme. The amount of hydrogen peroxide, which is a byproduct of oxidative deamination of l-arginine by LGOX R305E, is proportional to the concentration of l-arginine in a range from 0 to 100 μM. The linear relationship is maintained around 1 μM of l-arginine. Thus, LGOX R305E is suitable for the determination of l-arginine.
Twisted π-Electron System Electrooptic Chromophores. Structural and Electronic Consequences of Relaxing Twist-Inducing Nonbonded Repulsions (2008)

The synthesis, structural and spectroscopic characterization, and nonlinear optical response properties of a “slightly” twisted zwitterionic 4-quinopyran electrooptic chromophore FMC, 2-{4-[1-(2-propylheptyl)-1H-pyridine-4-ylidene]cyclohexa-2,5-dienylidene}malononitrile, are reported. X-ray diffraction data and density functional theory (DFT) minimized geometries confirm that deletion of the four o-, o′-, o′′-, and o′′′-methyl groups in the parent chromophore TMC-2, 2-{4-[3,5-dimethyl-1-(2-propylheptyl)-1H-pyridin-4-ylidene]-3,5-dimethylcyclohexa-2,5-dienylidene}malononitrile, relaxes the arene−arene twist angle from 89.6 to 9.0°. These geometrical changes result in a significantly increased contribution of the quinoidal structure to the molecular ground state of FMC (versus TMC-2), reduced solvatochromic shifts in the optical spectra, and a diminished electric-field-induced second-harmonic (EFISH) generation derived molecular hyperpolarizability (μβ = −2340 × 10−48 esu of DFMC, the dendrimer derivative of FMC, vs −24000 × 10−48 esu of TMC-2) in CH2Cl2 at 1907 nm. Pulsed field gradient spin–echo (PGSE) NMR spectroscopy and EFISH indicate that the levels of FMC aggregation in solution are comparable to those of TMC-2 (monomers and dimers) in CH2Cl2 solution. B3LYP and INDO/S computation of chromophore molecular structure, aggregation, and hyperpolarizability trends are in good agreement with experiment.
Supplementary Figure 2 from Navitoclax (ABT-263) Reduces Bcl-x<sub>L</sub>–Mediated Chemoresistance in Ovarian Cancer Models (2023)

&lt;p&gt;PDF file - 680K, Overall Survival and Bcl-xL H Score.&lt;/p&gt;
Chemo-Enzymatic Synthesis of (R)- and (S)-2-Hydroxy-4-phenylbutanoic Acid via Enantio-Complementary Deracemization of (±)-2-Hydroxy-4-phenyl-3-butenoic Acid Using a Racemase-Lipase Two-Enzyme System (2005)

Deracemization of (±)-2-hydroxy-4-phenylbut-3-enoic acid was accomplished by lipase-catalyzed kinetic resolution ­coupled to mandelate racemase-mediated racemization of the non-reacting substrate enantiomer. Stepwise cyclic repetition of this ­sequence led to a single enantiomeric product, the stereochemical outcome of which could be controlled by switching between lipase-catalyzed acyl-transfer/ester hydrolysis reactions. Both enantio­meric products were easily transformed into (R)- and (S)-2-­hydroxy-4-phenylbutanoic acid, important building blocks for ACE-inhibitors.
Design and Analysis of Double End Drive Machine for Automation of Circular Welding Process (2020)

Abstract Welding is a joining process used to join materials, usually metals or thermoplastics, by causing coalescence. This is mostly done by melting the work-pieces and adding a filler material to form a pool of molten material that cools to become a strong joint, with pressure sometimes used in association with heat, or by itself, to produce the weld. The present work deals with a live task to design Double End Drive machine a SPM for manufacturing industry. The main aim is to design a machine to automate the circular welding process with the help of automatic drive. We have designed and analyzed various components of Double End drive machine and it is found that the newly designed machine is performing its intended function with expected effectiveness and efficiency. The newly designed machine automates the process of welding thereby reducing the work fatigue, Monotonous work and complexity of the process. The paper presents the details of design and analysis of components as well as pneumatic circuit to automate the welding process.
Extraction of Agricultural Phenological Parameters of Sri Lanka Using MODIS, NDVI Time Series Data (2016)

Management of crops is an essential part in the food production procedure. Having a thorough knowledge of growth stages of each crop is of paramount importance in this respect. Phenology (transplanting, panicle formation, flowering etc) is the study of cyclic and seasonal natural phenomena that are controlled by environmental and climatic factors. Monitoring the crop condition manually in the field is difficult and time consuming. Therefore recently, several methods have been introduced by using satellite derived vegetation indices. Extraction of phenological parameters is helpful for the purposes like irrigation management, nutrient management, health management, yield prediction and crop type mapping. Easily extracted parameters will be the important data base for agricultural researchers. This research is an attempt to extract paddy phenological parameters of Sri Lanka by using 16 years’ (2000 to 2015) Time series MODIS Normalised Difference Vegetation Index (NDVI), which is highly sensitive for the green vegetation and the data were analysed using SPIRITS and TIMESAT software's. Periodicity converter in SPIRITS and Savitzky Golay filtering in TIMESAT and SPIRITS are helpful in smoothing the time series which are perturbed by noise due to missing values and Clouds. Phenology is considered as a sensitive climate change indicator but, it is very essential to have a comprehensive familiarity about the method of water supply that the study area is irrigated or rain fed so as to eliminate the wrong interpretation. As results, average of long time series of NDVI profile for a few agro ecological zones of Sri Lanka with extracted seven parameters (Start of the season, End of the season, Length of the season, Booting date, Base value, Maximum NDVI during the Season, Amplitude) and generated phenological parameter maps are presented here. The crop phenology is a very important element of agricultural monitoring, to ensure the security of the food crop production.