gebhart/patrepeval huggingface dataset:
Highly selective standoff detection and imaging of trace chemicals in a complex background using single-beam coherent anti-Stokes Raman scattering (2011)

A non-destructive and highly selective method of standoff detection is presented and quantitatively evaluated. The method is found to be orders of magnitude more sensitive than previous coherent spectroscopy methods, identifying concentrations as low as 2 μg/cm2 of an explosive simulant mixed in a polymer matrix. The approach uses a single amplified femtosecond laser to generate high-resolution multiplex coherent anti-Stokes Raman scattering (CARS) spectra encompassing the fingerprint region (400−2500 cm−1) at standoff distance. Additionally, a standoff imaging modality is introduced, visually demonstrating similar sensitivity and high selectivity, providing promising results toward highly selective trace detection of explosives or warfare agents.
Nontrivial phenomena in laser light interaction with biotissues and blood (1994)

The panel discussion "Nontrivial phenomena in laser light interaction with biotissues and blood" was organized by the Scientific Research Institute of Physical Biomedicine at the GermanRussian Free Uthversity in Saratov. Moderators: Grigory E. Brill, Director of the InstitUte Valery V. Tuchin, Vice-Director of the InstitUte.
A concurrent examination of neurocognitive and language impairments in schizophrenia thought disorder (2013)

Frontiers Events is a rapidly growing calendar management system dedicated to the scheduling of academic events. This includes announcements and invitations, participant listings and search functionality, abstract handling and publication, related events and post-event exchanges. Whether an organizer or participant, make your event a Frontiers Event!
Face-to-face C6F5–[60]fullerene interaction for ordering fullerene molecules and application to thin-film organic photovoltaics (2010)

Treatment of [60]fullerene with potassium methylnaphthalenide and excess C(6)F(5)CH(2)Br afforded 1,4-bis(pentafluorobenzyl)[60]fullerene, the study of which showed that there is a face-to-face interaction between [60]fullerene and a perfluoro aromatic ring, allowing the molecule to be utilized for high-performance organic photovoltaic devices.
Double-Blind Comparison of Single Oral Doses of Oxaprozin, Aspirin, and Placebo for Relief of Post-Operative Oral Surgery Pain (1983)

The safety and efficacy of single oral doses of oxaprozin (1200 mg), aspirin (650 mg), and placebo were compared in an 8-hour double-blind study of 105 patients with moderate to severe post-operative dental-surgical pain. As measured by mean and cumulative mean scores obtained with the pain intensity and verbal pain relief scales, both active drugs produced significantly (p less than 0.05) more analgesia than did placebo. A significantly (p less than 0.05) greater proportion of patients reported effective (moderate or better) pain relief in the oxaprozin and aspirin groups than in the placebo group at 2, 3, and 4 hours; significant (p less than 0.05) differences between the oxaprozin and placebo groups continued for the entire 8 hours. Oxaprozin provided more pain relief than aspirin during the latter part of the study. There were no statistically significant differences, however, in any of the efficacy assessments between the oxaprozin and aspirin groups. By the end of the 8-hour observation, significantly (p less than 0.01) fewer patients taking oxaprozin (27%) than placebo (60%) were considered treatment failures and needed a replacement analgesic. Of those taking aspirin, 41% were treatment failures, not statistically different from the proportion of treatment failures with placebo. Adverse effects were infrequent, mild, comparable between the active treatment and placebo groups, and not definitely related to drug therapy. Oxaprozin provided greater pain relief than placebo and was comparable to aspirin during the first 4 hours of the evaluation; thereafter, greater pain relief occurred in the oxaprozin-treated group than either the aspirin or placebo-treated group.
Adaptive digital beamforming for angle estimation in jamming (2001)

A radar digital beamforming (DBF) architecture and processing algorithm is described for nulling the signal from a mainlobe electronic jammer and multiple sidelobe electronic jammers while maintaining monopulse angle estimation accuracy on the target. The architecture consists of a sidelobe jamming (SLJ) cancelling adaptive array (AA) followed by a mainlobe jamming (MLJ) canceller. A mainlobe maintenance (MLM) technique or constrained adaptation during the sidelobe cancellation process is imposed so that the results of the SLJ cancellation process do not distort the subsequent mainlobe cancellation process. The SLJ signals and the MLJ signals are thus cancelled sequentially in separate processes. This technique was developed for improving radar processing in determining the angular location of a target, and specifically for improving the monopulse technique by maintaining the accuracy of the target echo monopulse ratio in the presence of electronic jamming by adaptive suppression of the jamming signals before forming the monopulse sum and difference beams.
Efficient immune responses in mice lacking N‐region diversity (1995)

Mice with a null mutation in the terminal deoxynucleotidyl transferase (TdT) gene harbor immunoglobulin and T cell receptor repertoires essentially devoid of N-region diversity. Consequently, the CDR3 loops important for antigen recognition are shorter and considerably less diverse than those of wild-type controls. We find surprisingly normal immune responses in TdT0 mice, as regards both efficiency and specificity. This provokes a reconsideration of the assumption that N-region diversity is required for an effective T and B cell repertoire.
Coherent hollow-core waveguide bundles for thermal imaging (2010)

There has been very little work done in the past to extend the wavelength range of fiber image bundles to the IR range. This is due, in part, to the lack of IR transmissive fibers with optical and mechanical properties analogous to the oxide glass fibers currently employed in the visible fiber bundles. Our research is aimed at developing high-resolution hollow-core coherent IR fiber bundles for transendoscopic infrared imaging. We employ the hollow glass waveguide (HGW) technology that was used successfully to make single-HGWs with Ag/AgI thin film coatings to form coherent bundles for IR imaging. We examine the possibility of developing endoscopic systems to capture thermal images using hollow waveguide fiber bundles adjusted to the 8-10?mum spectral range and investigate the applicability of such systems. We carried out a series of measurements in order to characterize the optical properties of the fiber bundles. These included the attenuation, resolution, and temperature response. We developed theoretical models and simulation tools that calculate the light propagation through HGW bundles, and which can be used to calculate the optical properties of the fiber bundles. Finally, the HGW fiber bundles were used to transmit thermal images of various heated objects; the results were compared with simulation results. The experimental results are encouraging, show an improvement in the resolution and thermal response of the HGW fiber bundles, and are consistent with the theoretical results. Nonetheless, additional improvements in the attenuation of the bundles are required in order to be able to use this technology for medical applications.
Yield and chemical composition of Citrus essential oils as affected by drying pretreatment of peels (2011)

Citrus peel essential oils have an impressive range of food and medicinal uses. In the present study we investigated the variation in the yield and chemical composition of the essential oils isolated from fresh, ambient-, and oven-dried peels of three Citrus species namely Citrus reticulata (C. reticulata), Citrus sinensis (C. sinensis) and Citrus paradisii (C. paradisii). The hydro-distilled essential oil content from fresh-, ambient-, and oven-dried peels of C. reticulata, C. sinensis and C. paradisii ranged from 0.30-0.50, 0.24-1.07 and 0.20- 0.40 g/100 g, respectively. The maximum amount of the oil was determined in oven-dried while the minimum in fresh peel samples. Using GC and GC/MS, a total of 16-27, 17-24 and 18-40 chemical constituents were identified in the peel essential oils of C. reticulate, C. sinensis and C. paradisii, respectively. The content of limonene, the most prevalent chemical constituent, detected in these essential oils, ranged from 64.1-71.1% (C. reticulata), 66.8-80.9% (C. sinensis) and 50.8-65.5% (C. paradisii). The yield and content of most of the chemical components including limonene (the principal chemical compound detected) of the tested essential oils varied significantly (p < 0.05) with respect to drying treatments and species employed.
1031 RECENT ADVANCES IN UNDERSTANDING PHYSIOLOGICAL ADAPTATIONS TO RESISTANCE EXERCISE (1993)

Dudley, G FACSM, Chair; Evans, W FACSM; Slaron, R; Kraemer, W FACSM; Komi, P FACSM; Tesch, P FACSM; Booth, F FACSM; Wright, J
Towards a multi-level neural architecture that unifies self-intended and imitated arm reaching performance (2014)

Dexterous arm reaching movements are a critical feature that allow human interactions with tools, the environment, and socially with others. Thus the development of a neural architecture providing unified mechanisms for actual, mental, observed and imitated actions could enhance robot performance, enhance human-robot social interactions, and inform specific human brain processes. Here we present a model, including a fronto-parietal network that implements sensorimotor transformations (inverse kinematics, workspace visuo-spatial rotations), for self-intended and imitation performance. Our findings revealed that this neural model can perform accurate and robust 3D actual/mental arm reaching while reproducing human-like kinematics. Also, using visuo-spatial remapping, the neural model can imitate arm reaching independently of a demonstrator-imitator viewpoint. This work is a first step towards providing the basis of a future neural architecture for combining cognitive and sensorimotor processing levels that will allow for multi-level mental simulation when executing actual, mental, observed, and imitated actions for dexterous arm movements.
Designing of EDFA with Inherently Low Transient Response for Optical Packet with Variable Condition of Traffic on WDM Environment (2007)

We present the designing method of EDFA to reduce transient response for optical packet on WDM environment. We adopted mid-GFF configuration to suppress the wavelength dependency taking increase of NF as a trade-off into account.
QUISAP: an environment for rapid prototyping of real-time systems (2002)

An environment for rapid prototyping and analysis of real-time systems is presented. The real-time system is specified using the language QUISAP and, from this specification, a model based on timed Petri nets for formal analysis and a prototype written in Ada for behavior analysis are built. Inappropriate handling of temporal constraints violations during prototype execution due to the Ada language can be improved with a new scheduling of tasks. Other improvements relate to the model of application objects, its definition, concurrency, and communication.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Practical techniques for defending against DDoS attacks (2005)

Summary form only given. Distributed denial of service (DDoS) attack is one of the most alarming threats on the Internet. DDoS attacks exhaust the critical resources of a target server in order to deny its services to the legitimate clients. In this paper, we propose a full set of techniques for defending against DDoS attacks. The complete countermeasure strategies are broken down to detection, segregation and mitigation techniques. Detection techniques are used to determine if any attack is taking place at any given moment. Segregation techniques aim to separate malicious traffic from legitimate traffic. Finally, the mitigation techniques are used to effectively minimizing the negative impact caused by DDoS attacks.
The Effect of Voice Ambulatory Biofeedback on the Daily Performance and Retention of a Modified Vocal Motor Behavior in Participants With Normal Voices (2015)

These findings suggest that although current ambulatory biofeedback approaches have potential to modify a vocal motor behavior, the modified behavior may not be retained after biofeedback removal. Future work calls for the testing of more innovative ambulatory biofeedback approaches on the basis of motor control and learning theories to improve retention of a desired vocal motor behavior.
Bacterial Hosts for Natural Product Production (2008)

Four bacterial hosts are reviewed in the context of either native or heterologous natural product production. E. coli, B. subtilis, pseudomonads, and Streptomyces bacterial systems are presented with each having either a long-standing or more recent application to the production of therapeutic natural compounds. The four natural product classes focused upon include the polyketides, nonribosomal peptides, terpenoids, and flavonoids. From the perspective of both innate and heterologous production potential, each bacterial host is evaluated according to biological properties that would either hinder or facilitate natural product biosynthesis.
Modelling and Analysis of Supply Chain Management Systems: An Editorial Overview (2000)

A. Gunasekaren, D. K. Macbeth, R. Lamming, Modelling and Analysis of Supply Chain Management Systems: An Editorial Overview, The Journal of the Operational Research Society, Vol. 51, No. 10, Part Special Issue: Modelling and Analysis in Supply Chain Management Systems (Oct., 2000), pp. 1112-1115
Fragmentation of Tertiary Cyclopropanol Compounds Catalyzed by Vanadyl Acetylacetonate. (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
Peptide Ligands Can Bind to Distinct Sites in Integrin αIIbβ3 and Elicit Different Functional Responses (1999)

The spatial relationship between the binding sites for two cyclic peptides, cyclo(S,S)KYGCRGDWPC (cRGD) and cyclo(S,S)KYGCHarGDWPC (cHarGD), high affinity analogs for the RGD and HLGGAKQAGDV peptide ligands, in integrin alphaIIbbeta3 (GPIIb-IIIa) has been characterized. For this purpose, cRGD and cHarGD were labeled with fluorescein isothiocyanate and tetramethylrhodamine 5-isothiocyanate, respectively. Both cyclic peptides were potent inhibitors of fibrinogen binding to alphaIIbbeta3, particularly in the presence of Mn2+; IC50 values for cRGD and cHarGD were 1 and <0.1 nM in the presence of Mn2+. Direct binding experiments and fluorescence resonance energy transfer analysis using the purified receptor showed that both peptides interacted simultaneously with distinct sites in alphaIIbbeta3. The distance between these sites was estimated to be 6.1 +/- 0.5 nm. Although cRGD bound preferentially to one site and cHarGD to the other, the sites were not fully specific, and each cyclic peptide or its linear counterpart could displace the other to some extent. The binding affinity of the cHarGD site was dramatically affected by Mn2+. cRGD, but not cHarGD, bound to recombinant beta3-(95-373) in a cation-dependent manner, indicating that the cRGD site is located entirely within this fragment. With intact platelets, binding of c-RGD and cHarGD to alphaIIbbeta3 resulted in distinct conformational alterations in the receptor as indicated by the differential exposure of ligand-induced binding site epitopes and also induced the opposite on membrane fluidity as shown by electron paramagnetic resonance analyses using 5-doxylstearic acid as a spin probe. These data support the concept the two peptide ligands bind to distinct sites in alphaIIbbeta3 and initiate different functional consequences within the receptor itself and within platelets.
Crystal structure of μ-carbonyl-1:2κ2C:C-carbonyl-1κC-(1η5-cyclopentadienyl)iodido-2κI-[μ-2-(pyridin-2-yl)ethene-1,1-diyl-1κC1:2κ2N,C1]ironpalladium(Fe—Pd) benzene monosolvate (2016)

The reaction of Cp(CO)<sub>2</sub>FeI with 2-ethynyl-pyridine under Sonogashira conditions [5% PdCl<sub>2</sub>(PPh<sub>3</sub>)<sub>2</sub>, 10% CuI, THF-NEt<sub>3</sub> (2:1)] afforded the title binuclear μ-pyridyl-vinyl-idene FePd complex (<b>FePd1</b>) as a benzene solvate, [FePd(C<sub>5</sub>H<sub>5</sub>)(C<sub>7</sub>H<sub>5</sub>N)I(CO)<sub>2</sub>]·C<sub>6</sub>H<sub>6</sub>, in a very low yield rather than the expected iron <i>o</i>-pyridyl-ethynyl complex Cp(CO)<sub>2</sub>Fe-C≡C-(2-C<sub>5</sub>H<sub>4</sub>N). The Fe and Pd atoms in <b>FePd1</b> are bridged by carbonyl and pyridyl-vinyl-idene ligands, the pyridyl N atom being bonded to the palladium atom. The use of equimolar amounts of PdCl<sub>2</sub> increases the yield of <b>FePd1</b> to 12%. The reaction pathway leading to <b>FePd1</b> is proposed.
Discovery of (meth)acrylate polymers that resist colonization by fungi associated with pathogenesis and biodeterioration (2020)

Fungi have major, negative socioeconomic impacts, but control with bioactive agents is increasingly restricted, while resistance is growing. Here, we describe an alternative fungal control strategy via materials operating passively (i.e., no killing effect). We screened hundreds of (meth)acrylate polymers in high throughput, identifying several that reduce attachment of the human pathogen <i>Candida albicans</i>, the crop pathogen <i>Botrytis cinerea</i>, and other fungi. Specific polymer functional groups were associated with weak attachment. Low fungal colonization materials were not toxic, supporting their passive, anti-attachment utility. We developed a candidate monomer formulation for inkjet-based 3D printing. Printed voice prosthesis components showed up to 100% reduction in <i>C. albicans</i> biofilm versus commercial materials. Furthermore, spray-coated leaf surfaces resisted fungal infection, with no plant toxicity. This is the first high-throughput study of polymer chemistries resisting fungal attachment. These materials are ready for incorporation in products to counteract fungal deterioration of goods, food security, and health.
Energy-aware non-cooperative resource allocation in relay-assisted MIMO IC considering circuit dissipated power (2012)

In this paper, non-cooperative, energy-efficient resource allocation in a MIMO relay-assisted interference channel is considered. The energy efficiency of a given terminal is defined as the ratio between the throughput of that terminal and the consumed power. As far as the computation of the consumed power is concerned, not only the transmit power, but also the power dissipated in terminal's electronic circuitry to operate the device is considered. We consider both the cases of power control and of joint power control and linear receiver design; in the former case we are able to prove that a unique Nash equilibrium exists, and that the best-response-dynamics is guaranteed to converge to the unique equilibrium; in the latter scenario existence of the Nash equilibrium is shown, while the convergence of the best-response-dynamics is only conjectured, based on numerical evidence. Numerical results are provided to show the merits of the proposed algorithms.
On-line Circulation of Software Product based on Dynamic License Control (2000)

Internet purchase is increasing according to the activation of Electronic Commerce. Currently, the hardware is main purchase items in the Electronic commerce. The on-line purchase of digital product, that is electronic file type of product, has many merits such as, does not cost in logistics, is ease of searching the product, and is possible of 'Try and Buy' system. But, actually digital products have not been major proudct because of tits piracy problem. The piracy problem of digital products comes from the lack of safety in DP license control technology. Current EC has no method to identify the object that has the right ot use the digital product. The protecting of object change is impossible and the protection of hacking is not enough and EC has any problems in efficient license control because of the incompletion of EC structure. In this paper, e propose the design and implementation of on-line DP circulation system, which can activate on-line circulation of DP in EC and protect its piracy, by using the new license control technology, that is Dynamic License control technology.
Hepatic Lipid Molecules Synergize with Insulin to Induce GK Gene Expression (2008)

Hepatic glucokinase (GK, Hexokinase IV) plays a key role in maintaining glucose homoestasis. A variety of hormonal and nutritional stimuli, including insulin, regulate its activity by controlling its gene transcription. Here, we report a simple method to extract lipid molecules from rat livers and measure their effects on GK gene expression in primary rat hepatocytes using real‐time polymerase chain reaction. To this end, we observed that a lipid extract (LE) prepared rat liver by saponification, induces the levels of GK transcripts and potentates insulin‐mediated induction of GK gene expression. In hepatocytes, LE or 1 nM insulin alone induced GK mRNA by 7.6 ± 5.9‐ and 19.3 ± 12.4 –fold, respectively. The combination of LE and 1 nM insulin induced the GK expression by 155 ± 72 –fold, much higher than the sum of the induction fold by them individually (7.6+19.3=26.9), suggesting a synergy between LE and insulin. The synergy exists for all of the insulin concentrations examined ranging from 0.1 to 100 nM. LE does not induce the levels of GK transcripts in pancreatic islets and INS‐1 insulinoma cells, demonstrating a specific effect on hepatic GK expression. The actions of LE start as early as 3 hours and last at least 12 hours. Moreover, it does not alter the stability of GK transcripts, suggesting a transcriptional mechanism. We conclude that endogenous lipid molecules from liver can modulate hepatocyte GK gene expression.
Two bi‐functional cytochrome P450 CYP72 enzymes from olive ( Olea europaea ) catalyze the oxidative C‐C bond cleavage in the biosynthesis of secoxy‐iridoids – flavor and quality determinants in olive oil (2020)

Olive (Olea europaea) is an important crop in Europe, with high cultural, economic and nutritional significance. Olive oil flavor and quality depend on phenolic secoiridoids, but the biosynthetic pathway of these iridoids remains largely uncharacterized. We discovered two bifunctional cytochrome P450 enzymes, catalyzing the rare oxidative C-C bond cleavage of 7-epi-loganin to produce oleoside methyl ester (OeOMES) and secoxyloganin (OeSXS), both through a ketologanin intermediary. Although these enzymes are homologous to the previously reported Catharanthus roseus secologanin synthase (CrSLS), the substrate and product profiles differ. Biochemical assays provided mechanistic insights into the two-step OeOMES and CrSLS reactions. Model-guided mutations of OeOMES changed the product profile in a predictable manner, revealing insights into the molecular basis for this change in product specificity. Our results suggest that, in contrast to published hypotheses, in planta production of secoxy-iridoids is secologanin-independent. Notably, sequence data of cultivated and wild olives point to a relation between domestication and OeOMES expression. Thus, the discovery of this key biosynthetic gene suggests a link between domestication and secondary metabolism, and could potentially be used as a genetic marker to guide next-generation breeding programs.