gebhart/patrepeval huggingface dataset:
A DC voltage dependent switchable acoustically coupled BAW filter based on BST-on-silicon composite structure (2012)

A DC voltage dependent switchable, bulk acoustic wave (BAW) filter is presented in this paper. The filter has a composite structure consisting of a barium strontium titanate (BST) layer sandwiched between top and bottom platinum (Pt) electrodes deposited on silicon (Si) and oxide (SiO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> ) layers. The electrostrictive property of ferroelectric BST allows for the filter to be turned on and off by applying an electric field across the BST layer. The Si and SiO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> layers are used to increase the overall quality factor and mechanical strength of the structure. When the filter is turned on, the 3 dB bandwidth is 43 MHz at a center frequency of 1.08 GHz. After resonating out the input and output static capacitances of the filter using shunt inductors, the filter exhibits an insertion loss of 8.5 dB with the application of 25 V DC bias. The return loss and out-of-band rejection of the filter are 18 dB and 29 dB, respectively. In its off state, with no DC bias applied, the isolation between input and output ports is 37 dB.
Molecular therapeutics: is one promiscuous drug against multiple targets better than combinations of molecule-specific drugs? (2003)

Two manuscripts from the same group in this issue illustrateimportant aspects relevant to the discovery and development of molecule-targeted therapeutics. In the first paper, Ciardiello et al. [(1)][1] report the ability of the VEGFR-2[3][2] (Flk-1 and KDR) tyrosine kinase inhibitor ZD6474 to also
Restriction Pattern Analysis by High-performance Liquid Chromatography of PCR-amplified 16S rDNA Fragments from Scum-forming Bacteria in Activated Sludge. (1997)

High-performance liquid chromatography (HPLC) with an anion-exchange nonporous column was used to analyze restriction fragment length polymorphism (RFLP) of the 16S ribosomal DNA (rDNA) of scum-forming actinomycetes found in three different activated sludge plants. 16S rDNA fragments from washed scum samples were amplified by PCR and cloned into plasmid vectors. The 16S rDNA inserts in the plasmids were reamplified in vitro, cut with restriction endonucleases, and separated directly by HPLC. Compared to conventional agarose electrophoresis, the HPLC system used allowed better separation of fragments up to 500bp. The HPLC-RFLP patterns of the scum clones were compared with those of PCR-amplified 16S rDNAs from authentic strains and with computer-predicted restriction patterns of the available 16S rDNA data on the actinomycetes. 16S rDNA-RFLP comparisons indicated that the predominat scum-forming bacteria were Gordona amarae in two activated sludge plants and Rhodococcus sp. in the remaining one. These findings agreed well with results of lipoquinone profiling of the scum performed concurrently. The results of this study indicated that a combination of 16S rDNA-RFLP analysis and quinone profiling should provide a more powerful non-cultivating tool for the identification of scum-forming bacteria in activated sludge.
Markov Chain Monte Carlo Algorithms and their Applications to Petroleum Reservoir Characterization (2003)

This thesis consists of papers on stochastic reservoir characterization and Markov chain Monte Carlo algorithms. Stochastic reservoir models are very complex and naturally spatial and high dimensio ...
USE OF THE FREEZING SOIL HEAVE STRESS SYSTEM TO EVALUATE THE FROST SUSCEPTIBILITY OF SOILS (1974)

The M.I.T. Freezing Soil Heave Stress System has been developed to evaluate the frost susceptibility of soils. Measurements of heave stress generation with time are made in constant volume, open system test. From a plot of heave stress versus logarithm of time an evaluation of relative frost susceptibility can be made. Data are presented from tests in the prototype equipment used for development and the Freezing Soil Heave Stress system itself which were run for the purpose of standardizing test equipment and procedures. Tests using the prototype equipment indicate the effects of variation of compaction of water content, elimination of the overnight equilibration period and scalping of material larger than the #4 sieve. Tests using Freezing Soil Heave Stress System were used to study the effects of testing temperatures which were shown to strongly influence the test results. A recommendation is made for a thermal regime to be used in subsequent testing. This recommendation and classification scheme are only tentative and final standardization will depend upon the development of a correlation between the test results and field performance. /FHWA/
Novel signal peptides improve the secretion of recombinant Staphylococcus aureus Alpha toxinH35L in Escherichia coli (2017)

Secretion of heterologous proteins into Escherichia coli cell culture medium offers significant advantages for downstream processing over production as inclusion bodies; including cost and time savings, and reduction of endotoxin. Signal peptides play an important role in targeting proteins for translocation across the cytoplasmic membrane to the periplasmic space and release into culture medium during the secretion process. Alpha toxinH35L (ATH35L) was selected as an antigen for vaccine development against Staphylococcus aureus infections. It was successfully secreted into culture medium of E. coli by using bacterial signal peptides linked to the N-terminus of the protein. In order to improve the level of secreted ATH35L, we designed a series of novel signal peptides by swapping individual domains of modifying dsbA and pelB signal peptides and tested them in a fed-batch fermentation process. The data showed that some of the modified signal peptides improved the secretion efficiency of ATH35L compared with E. coli signal peptides from dsbA, pelB and phoA proteins. Indeed, one of the novel signal peptides improved the yield of secreted ATH35L by 3.5-fold in a fed-batch fermentation process and at the same time maintained processing at the expected site for signal peptide cleavage. Potentially, these new novel signal peptides can be used to improve the secretion efficiency of other heterologous proteins in E. coli. Furthermore, analysis of the synthetic signal peptide amino acid sequences provides some insight into the sequence features within the signal peptide that influence secretion efficiency.
A linear equalizer for high-speed APD-based integrate-and-dump receivers (2005)

A linear minimum mean-square error (LMMSE) equalizer for avalanche-photodiode (APD) based integrate-and- dump receivers is designed to compensate for intersymbol- interference (ISI) introduced by the APD's random impulse response. Recent work on the characterization of the joint probability distribution of the APD's gain and buildup-time are adopted and utilized to determine the mean and correlation matrix of the APD-based receiver's random impulse response. This LMMSE equalizer is shown to improve the bit-error- rate dramatically at high transmission rates, resulting in an improvement in the receiver sensitivity by approximately 2.3 dB at 15GHz. Index Terms—Avalanche photodiodes, equalization, random impulse response, bit-error-rate, receiver sensitivity.
Retractable-barb needle for breast lesion localization: use in 60 cases. (1988)

A needle system with a retractable barb was developed for localization of nonpalpable breast lesions. The system can be repositioned without major adjustments and strongly anchors to breast tissue, eliminating failure due to dislodgment or transection of the localizing wire. Its use may necessitate fewer confirmatory radiographs, resulting in decreased radiation exposure. In addition, the needle can be retracted during surgery, to ease extraction of the specimen.
DESERT Underwater: An NS-Miracle-based framework to design, simulate, emulate and realize test-beds for underwater network protocols (2012)

DESERT Underwater (short for DEsign, Simulate, Emulate and Realize Test-beds for Underwater network protocols) is a complete set of public C/C++ libraries to support the design and implementation of underwater network protocols. Its creation stems from the will to push the studies on underwater networking beyond simulations. Implementing research solutions on actual devices, in fact, is of key importance to realize a communication and networking architecture that allows heterogeneous nodes to communicate reliably in the underwater environment. In this paper, we first discuss the rationale behind this work, and, then we list and briefly describe all the DESERT Underwater libraries currently implemented. In line with the current trends in underwater networking, our approach makes it possible to reuse the same code prepared for simulations in order to realize underwater network prototypes. We also present some preliminary tests that confirm the feasibility of the proposed solution for the design and evaluation of underwater network protocols. In this perspective, we believe that DESERT Underwater is a useful tool to profitably develop and test real world applications.
Novel TriBand RF Rectifier Design for Wireless Energy Harvesting (2014)

In this paper, the design of a 10 mW concurrent triband RF rectifier at 1050 , 2050 and 2600 MHz using the high impedance transmission line with two short stubs is presented. Experimental results show that the efficiency is achieved 59.2 % at 1050 MHz, 35.6 % at 2050 MHz and 52.2 % at 2600 MHz. Compared to the state-of-the-art of multi-band rectifiers, the proposed triband rectifier has the ability to harvest RF energy from the corresponding operating frequencies sources.
Internet of Things for Structural Health Monitoring (2016)

The Internet revolution led to the interconnection between people at an unprecedented scale and pace. The ability of the sensor networks to send data over the Internet further enhanced the scope and usage of the sensor networks. The Internet uses unique address to identify the devices connected to the network. Structural Health Monitoring (SHM) implies monitoring of the state of the structures through sensor networks in an online mode and are pertinent to aircraft and buildings. SHM can be further divided into two categories: global health monitoring and local health monitoring. Continuous online SHM would be an ideal solution. SHM is performed by using acoustic sensors, ultrasonic sensors, strain gauges, optical fibers, and so on. Video cameras can also be used for SHM. SHM can be achieved in real-time and rich analytics. With the advent of smart sensors—sensors with programmable microprocessors, memory, and processing—has reduced load of central data processing, communication overhead while proving continuous SHM status.
Data-Driven Participant Selection and Bandwidth Allocation for Heterogeneous Federated Edge Learning (2022)

&lt;p&gt;This work has been submitted to the IEEE for possible publication. Copyright may be transferred without notice, after which this version may no longer be accessible.&lt;/p&gt;
Innovation of Transfusion Medicine with iPS Cells (2017)

血小板と赤血球は，ともに生体維持に重要な役割を果たしている循環血球成分であり，血小板は止血作用を，赤血球は全身への酸素運搬を担う．献血血液製剤は，重度の血小板減少および貧血を来たした患者に投与されて多くの命を救ってきた一方，供給不安，同種免疫反応，感染症などのリスクが存在し，高齢社会に伴う絶対的な献血ドナー不足も予測されている．これに対し，iPS細胞から製造される血液製剤はドナーに依存しない供給が可能であり，これらの問題の解決が見込まれている．現在，血小板の大量製造技術はおおよそ確立して臨床応用が視野に入っており，赤血球についてはさらなる大量製造や成人型赤血球産生などの技術的課題が存在するが，克服に向けて研究が進められている．再生医療の観点からは，血液製剤は造腫瘍性の懸念が低いため，早期の普及が見込まれ，他のiPS細胞応用医療を牽引することも期待される．
Bell's Palsy: A Review of Treatment Using Antiviral Agents (2006)

The use of acyclovir in the treatment of Bell's palsy remains controversial. Additional, adequately powered, randomized, placebo-controlled trials are needed to definitively support its use. For the time being, the evidence reviewed in this article would favor the combination of acyclovir and prednisone if commenced within the first 72 hours of symptom onset.
Sleep spindle detection in sleep EEG signal using sparse bump modeling (2011)

Sleep spindle is the hallmark of second stage of sleep in human being, which is defined as a rhythmic sequence with waxing and waning waves, whose frequency is approximately between 8 to 14 Hz, and its time duration is between 0.5 to 2 seconds. Bump modeling is a method for extracting regions with higher amounts of energy in a related time-frequency map. The bump model of the sleep spindle consists of a group of high energy bumps concentrating in approximately 8 to 14 Hz frequency band. In this study, it will be shown that the power of bumps of EEG can be used in automated detection of sleep spindle. The presented method sensitivity is 99.41% which shows high correctly detection rate, and its error detection ratio is 14.51%, which demonstrates the low dependency of the presented algorithm to the subjects, and its low false detection ratio.
Über den Mechanismus der neuen Purin-Synthese (Säureamid-Reaktionen ; 35) (1964)

Die Bildung von Purinen aus Aminoacetonitrilen und Formamidinacetat erfolgt über intermediär entstehende 4-Amino-imidazole und anschließende Anellierung des Pyrimidinrings.
A CASE OF PRIMARY ACQUIRED AGAMMAGLOBULINEMIA ACCOMPANIED WITH NODULAR LYMPHOID HYPERPLASIA OF THE GASTROINTESTINAL TRACT FROM DUODENUM TO HALF OF JEJUNUM (1979)

原発性後天性無γ-globulin血症, WHOの分類試案ではvariable common immunodeficiencyに属するとおもわれる33才の男性症例を経験したので報告する.患者は乳幼児期に麻疹,流行性耳下腺炎に罹患したが正常に回復した.とくに感冒に罹患しやすいということはなかつた. 20才頃から肺炎に反復罹患し,再三37.5°C前後の微熱を生じ,胆嚢炎にも罹患したことがある. 32才のとき無γ-globulin血症を発見された.下痢の反復など消化器症状はない.本症例は,末梢リンパ球数は正常であるが,骨髄に形質細胞はほとんど認められない.免疫グロブリンはIgG, IgA, IgM, IgD, IgEすべてにきわめて低値を示した. T cell, B cel1はほぼ正常に存し,皮内反応(PPD, Candida)は正常に反応した.消化管X線検査,内視鏡では十二指腸球部から空腸上部にかけて微細な半円形の隆起性病変をびまん性に多数みとめ,結節性リンパ過形成(nodular lymphoid hyperplasia; NLH)とおもわれた.以上のように十二指腸から空腸にかけてNLHを有する原発性後天性無γ-globulin血症の1例について報告するとともに,本邦報告例の集計を行ない報告例との比較検討をおこなつた.
Cell‐free expression profiling of E. coli inner membrane proteins (2010)

The high versatility and open nature of cell-free expression systems offers unique options to modify expression environments. In particular for membrane proteins, the choice of co-translational versus post-translational solubilization approaches could significantly modulate expression efficiencies and even sample qualities. The production of a selection of 134 alpha-helical integral membrane proteins of the Escherichia coli inner membrane proteome focussing on larger transporters has therefore been evaluated by a set of individual cell-free expression reactions. The production profiles of the targets in different cell-free expression modes were analyzed independently by three screening strategies. Translational green fluorescent protein fusions were analyzed as monitor for the formation of proteomicelles after cell-free expression of membrane proteins in the presence of detergents. In addition, two different reaction configurations were implemented and performed either by robotic semi-throughput approaches or by individually designed strategies. The expression profiles were specified for the particular cell-free modes and overall, the production of 87% of the target list could be verified and approximately 50% could already be synthesized in preparative scales. The expression of several selected targets was up-scaled to milliliter volumes and milligram amounts of production. As an example, the flavocytochrome YedZ was purified and its sample quality was demonstrated.
Preventing Drilling Fluid Induced Reservoir Formation Damage (2021)

Abstract During drilling of permeable reservoirs, drilling fluid may penetrate the formation and induce damage to the reservoir rock. Specifically, solids present in the drilling fluid may enter the formation and cause subsequent reduction in reservoir permeability in the area near the wellbore. When drilling with a water-based drilling fluid in a reservoir, various polymer-based additives are normally applied to reduce the filtration loss. These additives, such as Xanthan Gum, Poly Anionic Cellulose (PAC) and Starch may help in reducing losses to the formation in presence of small pore-throats and low differential pressures. If the pore throats exceed e.g. 20μm and differential pressures reach 500psi, these additives have little effect on reducing loss of drilling fluid to the formation and thereby little effect in preventing solids from entering the formation. Lost circulation is particularly challenging when losses occur in the reservoir section. This is because LCM treatment may create formation damages. Green et al. (SPE-185889) showed the nature of drilling fluid invasion, clean-up, and retention during reservoir formation drilling. They also showed the lack of direct relation between fluid loss and formation damage. In light of such ideas, a development of new Non-Invasive Fluid (NIF) additives was conducted. These additives were able to handle downhole pressure differences and create a preventative sealing of a permeable formation when applied into a solids-free drilling fluid. Ceramic discs of various permeability and mean pore-throat size were installed into a HTHP pressure cell. Drilling fluid was pumped through the cell and a filter cake was formed across the ceramic disc. A pressure of 500psi was applied and filtration loss was measured over a 30-minute period. Examples are herein presented showing how filter cake materials were applied into the drilling fluid and effectively sealing the permeable surface of the ceramic disc. Also, it will be shown how the filter cake was effectively removed from the discs using a breaker solution. Furthermore, a selection of experiments is presented, showing the possibility to heal lost circulation in permeable reservoirs without the presence of weighing materials, clays or drill-solids in the drilling fluid. A test was also conducted in such a way that the disc was fractured inside the test cell to investigate the impact on fluid loss.
Significant mobility improvement of amorphous In-Ga-Zn-O thin-film transistors annealed in a low temperature wet ambient environment (2018)

Transparent amorphous oxide semiconducting materials such as amorphous InGaZnO used in thin film transistors (TFTs) are typically annealed at temperatures higher than 250 °C to remove any defects present and improve the electrical characteristics of the device. Previous research has shown that low cost and low temperature methods improve the electrical characteristics of the TFT. With the aid of surface and bulk characterization techniques in comparison to the device characteristics, this work aims to elucidate further on the improvement mechanisms of wet and dry annealing ambients that affect the electrical characteristics of the device. Secondary Ion Mass Spectrometry results show that despite outward diffusion of –H and –OH species, humid annealing ambients counteract outward diffusion of these species, leading to defect sites which can be passivated by the wet ambient. X-ray Photoelectron Spectroscopy results show that for devices annealed for only 30 min in a wet annealing environment, the concentration of metal-oxide bonds increased by as much as 21.8% and defects such as oxygen vacancies were reduced by as much as 18.2% compared to an unannealed device. Our work shows that due to the oxidizing power of water vapor, defects are reduced, and overall electrical characteristics are improved as evidenced with the 150 °C wet O2, 30 min annealed sample which exhibited the highest mobility of 5.00 cm2/V s, compared to 2.36 cm2/V s for a sample that was annealed at 150 °C in a dry ambient atmospheric environment for 2 h.
Development of Scaffold Building Units and Assembly for Tissue Engineering Using Fused Deposition Modelling (2009)

In tissue engineering (TE), a porous scaffold structure of biodegradable material is required as a template to guide the proliferation, growth and development of cells appropriately in three dimensions. The scaffold must meet design requirements of appropriate porosity, pore size and interconnected structure to allow cell proliferation and adhesion. This paper presents a methodology for design and manufacture of TE scaffolds with varying porosity by employing open structure building units and Fused Deposition Modeling (FDM) rapid prototyping technique. A computer modeling approach for constructing and assembly of three-dimensional unit cell structure is presented to provide a solution of scaffolds design that can potentially meet the diverse requirements of TE applications. A parametric set of open polyhedral unit cells is used to assist the user in designing the required micro-architecture of the scaffold with required porosity and pore size and then the Boolean operation is used to create the scaffold of a given CAD model from the designed microstructure. The procedure is verified by fabrication of physical scaffolds using the commercial FDM system.
The effect of the dielectric end groups on the positive bias stress stability of N2200 organic field effect transistors (2021)

Bias stress degradation in conjugated polymer field effect transistors is a fundamental problem in disordered materials and can be traced back to interactions of the material with environmental species [H. Sirringhaus, Adv. Mater. 21, 3859–3873 (2009); S. Park et al., Adv. Funct. Mater. 30 1904590-1–1904590-21 (2020); and W. H. Lee et al., Adv. Mater. 26, 1660–1680 (2014)], as well as fabrication-induced defects [H. Klauk, Organic Electronics: Materials, Manufacturing, and Applications (Wiley, 2006) and M. Nikolka et al., Nat. Mater. 16, 356–362 (2017)]. However, the effect of the end groups of the polymer gate dielectric and the associated dipole-induced disorder on bias stress stability has not been studied so far in high-performing n-type materials, such as N2200 [H. Yan et al., Nature 457, 679–686 (2009) and S. Brixi et al., Sci. Rep. 10, 4014 (2020)]. In this work, the performance metrics of N2200 transistors are examined with respect to dielectrics with different end groups [Cytop-M (CTL-809M) and Cytop-S (CTX809-SP2) as purchased from AGC Inc.]. We hypothesize that the polar end groups would lead to increased dipole-induced disorder and worse performance [H. Sirringhaus, Adv. Mater. 21, 3859–3873 (2009); N. B. Ukah et al., J. Polym. Sci., Part B: Polym. Phys. 51, 1533–1542 (2013); and S. Kim et al., Sci. Technol. Adv. Mater. 19, 486–494 (2018)]. The long-time annealing scheme at lower temperatures used in this paper is assumed to lead to better crystallization by allowing the crystalline domains to reorganize in the presence of the solvent [C. S. Kim et al., Appl. Phys. Lett. 93, 103302 (2008)]. It is hypothesized that the higher crystallinity could narrow down the range at which energy carriers are induced and thus decrease the gate dependence of the mobility. The results show that the dielectric end groups do not influence the bias stress stability of N2200 transistors. However, long annealing times result in a dramatic improvement in bias stress stability, with the most stable devices having a mobility that is only weakly dependent on or independent of gate voltage.
The Impact of Periodontal Therapy and the Adjunctive Effect of Antiseptics on Breath Odor‐Related Outcome Variables: A Double‐Blind Randomized Study (2005)

The results of this study indicate that in patients with moderate periodontitis, initial periodontal therapy including tongue scraping did not have a significant effect on the microbial load of the tongue and had only a weak impact on the VSC level, except when combined with a mouthrinse. Saliva incubation can be used as an indirect way to score breath odor. It offers simplicity, objectivity, and is less invasive.