gebhart/patrepeval huggingface dataset:
Very low chirping of InGaAs-InGaAlAs MQW DFB BRS lasers under 10 Gbit/s modulation (1993)

The ability of the InGaAs/InGaAlAs multi-quantum-well (MQW) system to achieve ultra-low-chirp operation under 10-Gb/s operation is experimentally demonstrated. The MQW active layer has been grown by a solid-source molecular beam epitaxy (MBE) method. Two metalorganic chemical vapor deposition (MOCVD) regrowths were used to fabricate the distributed-feedback (DFB) buried ridge structure (BRS) lasers. DFB BRS lasers with good static and spectral performance have been obtained. Under 10-Gb/s modulation those lasers exhibited a chirp value as low as 0.11 nm at -20 dB, which is attributed to an extremely small phase-amplitude coupling coefficient of 1.8. An analysis of the AM and FM modulated laser field under digital pseudorandom signal confirms the observed spectra and shows the possibility of an optimum spectrum width for lasers with small chirping.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Automatic Classification of Sub-Techniques in Classical Cross-Country Skiing Using a Machine Learning Algorithm on Micro-Sensor Data (2017)

The automatic classification of sub-techniques in classical cross-country skiing provides unique possibilities for analyzing the biomechanical aspects of outdoor skiing. This is currently possible due to the miniaturization and flexibility of wearable inertial measurement units (IMUs) that allow researchers to bring the laboratory to the field. In this study, we aimed to optimize the accuracy of the automatic classification of classical cross-country skiing sub-techniques by using two IMUs attached to the skier's arm and chest together with a machine learning algorithm. The novelty of our approach is the reliable detection of individual cycles using a gyroscope on the skier's arm, while a neural network machine learning algorithm robustly classifies each cycle to a sub-technique using sensor data from an accelerometer on the chest. In this study, 24 datasets from 10 different participants were separated into the categories training-, validation- and test-data. Overall, we achieved a classification accuracy of 93.9% on the test-data. Furthermore, we illustrate how an accurate classification of sub-techniques can be combined with data from standard sports equipment including position, altitude, speed and heart rate measuring systems. Combining this information has the potential to provide novel insight into physiological and biomechanical aspects valuable to coaches, athletes and researchers.
Percutaneous Aspiration Embolectomy Using Guiding Catheter for the Superior Mesenteric Artery Embolism (2015)

Percutaneous aspiration embolectomy is a useful tool in recanalization of embolic occlusion of the SMA in select patients.
Prism = methodology + process-oriented environment (1990)

A description is given of Prism, an experimental process-oriented environment supporting methodical development, instantiation, and execution of software process models. Also described is an architecture that captures this model in its various components. The architecture has been designed to hold a product software process description, the life cycle of which is supported by an explicit representation of a higher level (or meta) process description. Also described is the nine-step Prism methodology for building and tailoring process models, and several scenarios to support this description are given. In Prism, process models are built using a hybrid process modeling language, which is based on a high-level Petri net formalism and rules. The Prism prototype has been implemented on UNIX, GRAS database for attributed graph structures, and the Sunview user interface. >
Biochemical Characterization and Crystallographic Structure of an Escherichia coli Protein from the Phosphotriesterase Gene Family (1998)

Phosphotriesterase homology protein (PHP) is a member of a recently discovered family of proteins related to phosphotriesterase, a hydrolytic, bacterial enzyme with an unusual substrate specificity for synthetic organophosphate triesters and phosphorofluoridates, which are common constituents of chemical warfare agents and agricultural pesticides. No natural substrate has been identified for phosphotriesterase, and it has been suggested that the enzyme may have evolved the ability to hydrolyze synthetic compounds in bacteria under selective pressure to meet nutritional needs. PHP, which has 28% sequence identity with phosphotriesterase, may belong to the family of proteins from which phosphotriesterase evolved. Here we report the cloning, expression, initial characterization, and high-resolution X-ray crystallographic structure of PHP. Biochemical analysis shows that PHP is monomeric and binds two zinc ions per monomer. Unlike phosphotriesterase, PHP does not catalyze the hydrolysis of nonspecific phosphotriesters. The structure, similar to that of phosphotriesterase, consists of a long, elliptical alpha/beta barrel and has a binuclear zinc center in a cleft at the carboxy end of the barrel at the location of the presumptive active site.
Distributed Enhanced Inter-Cell Interference Coordination (eICIC) in LTE-Advanced HetNets: A Potential Game Approach (2015)

In this paper we propose a distributed algorithm for jointly optimizing almost blank subframe (ABS) and cell selection bias (CSB) patterns in Long Term Evolution- Advanced (LTE-A) heterogeneous networks (HetNets). We formulate the optimization problem as an exact potential game, where a Nash equilibrium point is guaranteed to be achieved within finite number of plays. Through simulations, we are able to demonstrate the fast convergence of the algorithm, an increase in average user rate, and a tremendous improvement on the service fairness of the users.
Evolutionary and genotypic analyses of global porcine epidemic diarrhea virus strains (2018)

Porcine epidemic diarrhea virus (PEDV), which re-emerged in China in October 2010, has spread rapidly worldwide. Detailed analyses of the complete genomes of different PEDV strains are essential to understand the relationships among re-emerging and historic strains worldwide. Here, we analysed the complete genomes of 409 strains from different countries, which were classified into five subgroup strains (i.e., GI-a, GI-b, GII-a, GII-b, and GII-c). Phylogenetic study of different genes in the PEDV strains revealed that the newly discovered subgroup GII-c exhibited inconsistent topologies between the spike gene and other genes. Furthermore, recombination analysis indicated that GII-c viruses evolved from a recombinant virus that acquired the 5' part of the spike gene from the GI-a subgroup and the remaining genomic regions from the GII-a subgroup. Molecular clock analysis showed that divergence of the GII-c subgroup spike gene occurred in April 2010, suggesting that the subgroup originated from recombination events before the PEDV re-emergence outbreaks. Interestingly, Ascaris suum, a large roundworm occurring in pigs, was found to be an unusual PEDV host, providing potential support for cross-host transmission. This study has significant implications for understanding ongoing global PEDV outbreaks and will guide future efforts to develop effective preventative measures against PEDV.
Erratum to “Temperature Dependence of the Elastic Constants of Doped Silicon” (2015)

There is an error in one set of values listed in Table III, page 735. The cell in the 4th row from the bottom (Ring ) and rightmost column (P6.6) should read “-3.05 / -58.10 / 19.46”, not “-58.10 / -30.99 / 19.46”.
Studies on Seven-membered Ring Derivatives. IV. 6, 10-Dimethylbicyclo-[5.3.0] decanones obtained from Guaiol (1965)

levorotatory and dextrorotatory 6, 10-Dimethylbicyclo [5.3.0] decan-3-ones (IIIa and IIIb) were derived from guaiol (I), and the former was converted into dexitrorotatory 6, 10-dimethylbicyclo [5.3.0] decan-4-one (XI).
Studies on Anthracenes. 2. Synthesis and Cytotoxic Evaluation of 9-Acyloxy 1,8-Dichloroanthracene Derivatives. (2001)

The synthesis and cytotoxic evaluation of 9-acyloxy 1,8-dichloroanthracene derivatives are described. The system selectively reduces the carbonyl group flanked by the peri substituents of the anthracenediones to give the corresponding 1,8-dichloro-9(10H)-anthracenone. Simple acylation of anthracenone occurred with appropriate acyl chlorides in CH2Cl2 with a catalytic amount of pyridine to give the 9-acyloxy-1,8-dichloroanthracene derivatives. Considerable interest has developed in the mechanism of how anthracenones achieve this desirable selectivity. These compounds were evaluated in vitro for their ability to inhibit the growth of human oral epidermoid carcinoma cells (KB cell line), human cervical carcinoma cells of ME 180 (GBM 8401) and Chinese hamster ovary (CHO) cells, respectively, as compared to mitoxantrone. The in vitro cytotoxicity evaluation of 9-acyloxy 1,8-dichloroanthracenes against these above cell lines revealed for most of the compounds a cytotoxic potency lower than that of mitoxantrone. The most active compounds were thus selected for further in vitro biological evaluation and structural modification.
A Novel Cooling Method and Comparison of Active Rewarming of Mildly Hypothermic Subjects (2017)

This study developed a novel and efficient model of hypothermia induction through exercise-induced convective afterdrop. Although there was not a clear benefit in either of the 2 active rewarming methods, AVA rewarming showed a nonsignificant trend toward greater shivering inhibition, which may be optimized by an improved interface.
Movable Polyrotaxane Surfaces for Modulating Cellular Adhesion via Specific RGD-Integrin Binding (2012)

Immobilizing bioactive molecules on the materials surfaces is one of the main strategies for creating functional bio-interfaces. In these kinds of bio-interfaces, the density of immobilized functional groups and the following physicochemical factors such as roughness, polarity and electrical charge have been thought important variables for regulating biological responses such as cell adhesion and differentiations. Here in this study, differences between rigidity and dynamically immobilized bioactive molecules on the biological responses will be discussed. In order to develop dynamic bio-interfaces, a polyrotaxane based block-copolymer containing clickable azide groups for conjugating various bioactive molecules was designed. Cell adhesive RGD peptide was then conjugated with the azide group by click reaction on both dynamic and rigid surfaces. As a result, cell adhesive RGD peptide immobilized on the dynamic bio-interfaces shows larger initial cell adhesion area, indicating that molecular dynamics of surface chemical groups is another important variable for the regulation of biological responses.
Influence of Graphite Characteristics on the Electrochemical Performance in Alkylcarbonate LiTFSI Electrolyte for Li-Ion Capacitors and Li-Ion Batteries (2013)

International audience
Science Goals and Mission Architecture of the Europa Lander Mission Concept (2022)

Abstract Europa is a premier target for advancing both planetary science and astrobiology, as well as for opening a new window into the burgeoning field of comparative oceanography. The potentially habitable subsurface ocean of Europa may harbor life, and the globally young and comparatively thin ice shell of Europa may contain biosignatures that are readily accessible to a surface lander. Europa’s icy shell also offers the opportunity to study tectonics and geologic cycles across a range of mechanisms and compositions. Here we detail the goals and mission architecture of the Europa Lander mission concept, as developed from 2015 through 2020. The science was developed by the 2016 Europa Lander Science Definition Team (SDT), and the mission architecture was developed by the preproject engineering team, in close collaboration with the SDT. In 2017 and 2018, the mission concept passed its mission concept review and delta-mission concept review, respectively. Since that time, the preproject has been advancing the technologies, and developing the hardware and software, needed to retire risks associated with technology, science, cost, and schedule.
Continuous sulfide supply enhanced autotrophic production of alcohols with Clostridium ragsdalei (2022)

Autotrophic syngas fermentation with clostridia enables the conversion of CO, CO<sub>2</sub>, and H<sub>2</sub> into organic acids and alcohols. The batch process performance of Clostridium ragsdalei was studied in fully controlled and continuously gassed (600 mbar CO, 200 mbar H<sub>2</sub>, 200 mbar CO<sub>2</sub>) stirred-tank bioreactors. The final ethanol concentration varied as function of the reaction conditions. Decreasing the pH from pH 6.0-5.5 at a temperature of 37 °C increased the ethanol concentration from 2.33 g L<sup>-1</sup> to 3.95 g L<sup>-1</sup>, whereas lowering the temperature from 37 to 32 °C at constant pH 6.0 resulted in a final ethanol concentration of 5.34 g L<sup>-1</sup> after 5 days of batch operation. The sulphur availability was monitored by measuring the cysteine concentration in the medium and the H<sub>2</sub>S fraction in the exhaust gas. It was found that most of the initially added sulphur was stripped out within the first day of the batch process (first half of the exponential growth phase). A continuous sodium sulfide feed allowed ethanol concentrations to increase more than threefold to 7.67 g L<sup>-1</sup> and the alcohol-to-acetate ratio to increase 43-fold to 17.71 g g<sup>-1</sup>.
O DESEMPENHO DAS EMPRESAS DO GRANDE ABC DE 2001 A 2008 (2011)

Essa pesquisa investiga empiricamente o desempenho das empresas do Grande ABC, região industrializada e cada vez mais representativa economicamente para o país. As sete cidades que representam a região, Santo André, São Bernardo do Campo, São Caetano do Sul, Diadema, Mauá, Ribeirão Pires e Rio Grande da Serra, tiverem nos últimos anos um crescimento econômico consideravelmente acima do crescimento do país e seu desenvolvimento tem impulsionado o crescimento do país. A análise empírica utiliza dados em painel e investiga o desempenho das firmas das sete cidades que compõe o Grande ABC durante os anos de 2001 a 2008 utilizando a metodologia multinível e três medidas de desempenho: ROA, OROA e ROE. A metodologia multinível possibilitou a identificação dos principais efeitos que estão associados ou não ao desempenho das empresas, entre esses efeitos estão o ano, a própria empresa, o subsetor, o setor e a cidade que a empresa se localiza. Entre as três medidas de desempenho utilizadas houve significativa convergência e, além disso, o estudo identificou que há um significativo efeito no desempenho das empresas associado ao ano e à própria empresa, além de mostrar que os setores, os subsetores e a cidade que a empresa se localiza não apresentam um efeito significativo associado ao\ndesempenho dessas firmas.
Identification of a 3-gene model as a powerful diagnostic tool for the recognition of ALK-negative anaplastic large-cell lymphoma (2012)

Anaplastic large-cell lymphomas (ALCLs) are a group of clinically and biologically heterogeneous diseases including the ALK(+) and ALK(-) systemic forms. Whereas ALK(+) ALCLs are molecularly characterized and can be readily diagnosed, specific immunophenotypic or genetic features to define ALK(-) ALCL are missing, and their distinction from other T-cell non-Hodgkin lymphomas (T-NHLs) remains controversial. In the present study, we undertook a transcriptional profiling meta-analysis of 309 cases, including ALCL and other primary T-NHL samples. Pathway discovery and prediction analyses defined a minimum set of genes capable of recognizing ALK(-) ALCL. Application of quantitative RT-PCR in independent datasets from cryopreserved and formalin-fixed paraffin-embedded samples validated a 3-gene model (TNFRSF8, BATF3, and TMOD1) able to successfully separate ALK(-) ALCL from peripheral T-cell lymphoma not otherwise specified, with overall accuracy near 97%. In conclusion, our data justify the possibility of translating quantitative RT-PCR protocols to routine clinical settings as a new approach to objectively dissect T-NHL and to select more appropriate therapeutic protocols.
Transient responses of a cylindrical lining in a thermoelastic medium based on the discontinuous interfacial model (2020)

As an important supporting structure in underground engineering, the lining is continuously exposed to harsh environments, such as high temperature and shock. This study takes lining and soil as the thermoelastic mediums of the Lord–Shulman model to investigate the transient responses of a cylindrical lining in thermoelastic mediums under the action of ramp-type heating. By considering the effects of thermal contact resistance and thermal wave impedance of the lining–soil interface, a discontinuous interfacial model was built for the lining–soil interface by adopting a thermal contact resistance model and the reflection and transmission principles of thermal waves. Based on the Laplace transform and its inversion, the solution of the dynamic response of the lining–soil system under the action of ramp-type heating was then obtained. The influences of the thermal contact resistance, thermal wave impedance ratio, thermal conductivity ratio, and specific heat ratio on the temperature increment and displacement were also explored. The comparison of the calculated results with the existing ones verifies the correctness of the results in this study.
Structure of homochiral carbonylchloro(3-trifluoroacetylcamphorato)platinum(II) (1991)

[Pt(Cl)(CO)(C 12 H 14 F 3 O 2 )] cristallise dans P2 1 avec a=11,035, b=7,216, c=9,824 A, β=99,61°, Z=2; affinement jusqu'a R=0,043. La maille contient deux molecules complexes homochirales. Les atomes Pt forment des colonnes en zigzag le long de [010] avec un empilement coplanaire du plan de coordination de Pt, la longueur Pt-Pt etant de 4,118 A
Wideband scanning array of spiral antennas for simultaneous transmit and receive (STAR) (2017)

We present a low profile (λ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">LOW</sub> /8) wideband slot spiral antenna array with high transmit/receive (Tx/Rx) isolation and scanning capability for STAR systems. To our knowledge, this is the first wideband STAR array with circular polarization and scanning capability. By suppressing Tx/Rx coupling, this array provides true full-duplex radios with a wideband beam steering antenna. Each array spiral consists of two arms for Tx and two more for Rx. To suppress grating lobes, the element spacing is kept at λ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">HIGH</sub> /2. Full wave simulations show the port-to-port Tx/Rx isolation is >40 dB at broadside across a 3 GHz bandwidth from 2-5 GHz (2.5:1). The port-to-port isolation exceeded 50 dB at frequencies below about 3 GHz. This level of port-to-port isolation is reduced to 30 dB when scanning to 30 degrees. Also, VSWR is <;2 and axial ratio <;3 dB.
Enantioselective Catalysis;150:Chiral-at-Metal (η6-p-Cymene)Ruthenium(II) Complexesof Binaphthyl Ligands - Synthesis, Characterization, andEnantioselective Catalysis (2003)

Neutral and cationic half-sandwich (η6-p-cymene)ruthenium complexes 9-12 with chiral Schiff base ligands derived from binaphthylamino derivatives and salicylaldehyde, diphenyl(2-formylphenyl)phosphane, and 2-pyridinealdehyde form two dia­stereomers which only differ in the metal configuration. From the diastereomeric mixtures of compounds 10 and 12 the major dia­stereomers crystallize, whereas for compound 9 both diastereomers co-crystallize in a 1:1 ratio in the same single crystal. In compounds 13 and 14 containing the reduced Schiff base ligands, the nitrogen atom of the secondary amine functionality becomes another chiral center. In solution at room temperature the various diastereomers interconvert rapidly. The new compounds were used as catalysts in the enantioselective transfer hydrogenation of acetophenone with 2-propanol and in the Diels-Alder reaction of cyclopentadiene with methacrolein.
Regioselective Generation of Single‐Site Iridium Atoms and Their Evolution into Stabilized Subnanometric Iridium Clusters in MWW Zeolite (2020)

Preparation of supported metal catalysts with uniform particle size and coordination environment is a challenging and important topic in materials chemistry and catalysis. In this work, we report the regioselective generation of single-site Ir atoms and their evolution into stabilized subnanometric Ir clusters in MWW zeolite, which are located at the 10MR window connecting the two neighboring 12MR supercages. The size of the subnanometric Ir clusters can be controlled by the post-synthesis treatments and maintain below 1 nm even after being reduced at 650 °C, which cannot be readily achieved with samples prepared by conventional impregnation methods. The high structure sensitivity, size-dependence, of catalytic performance in the alkane hydrogenolysis reaction of Ir clusters in the subnanometric regime is evidenced.
Mitochondrial-derived peptides in energy metabolism (2020)

Mitochondrial-derived peptides (MDPs) are small bioactive peptides encoded by short open-reading frames (sORF) in mitochondrial DNA that do not necessarily have traditional hallmarks of protein-coding genes. To date, eight MDPs have been identified, all of which have been shown to have various cyto- or metaboloprotective properties. The 12S ribosomal RNA (<i>MT-RNR1</i>) gene harbors the sequence for MOTS-c, whereas the other seven MDPs [humanin and small humanin-like peptides (SHLP) 1-6] are encoded by the 16S ribosomal RNA gene. Here, we review the evidence that endogenous MDPs are sensitive to changes in metabolism, showing that metabolic conditions like obesity, diabetes, and aging are associated with lower circulating MDPs, whereas in humans muscle MDP expression is upregulated in response to stress that perturbs the mitochondria like exercise, some mtDNA mutation-associated diseases, and healthy aging, which potentially suggests a tissue-specific response aimed at restoring cellular or mitochondrial homeostasis. Consistent with this, treatment of rodents with humanin, MOTS-c, and SHLP2 can enhance insulin sensitivity and offer protection against a range of age-associated metabolic disorders. Furthermore, assessing how mtDNA variants alter the functions of MDPs is beginning to provide evidence that MDPs are metabolic signal transducers in humans. Taken together, MDPs appear to form an important aspect of a retrograde signaling network that communicates mitochondrial status with the wider cell and to distal tissues to modulate adaptative responses to metabolic stress. It remains to be fully determined whether the metaboloprotective properties of MDPs can be harnessed into therapies for metabolic disease.
Ökologisches Verantwortungsbewusstsein und Ansatzpunkte zur Förderung im Unternehmen (2001)

Abstract In diesem Beitrag wird eine Konzeption zum ökologischen Verantwortungsbewusstsein vorgestellt, die sich auf folgende Teilbereiche bezieht: (a) auf das ökologische Denken bzw. Strukturwissen zu Umweltproblemen; (b) auf ökologische Kontrollvorstellungen zu Handlungsmöglichkeiten angesichts dieser Probleme sowie (c) auf ökologische Moral- bzw. Wertvorstellungen. Zuerst geht es um die theoretischen und empirischen Zusammenhänge zwischen diesen Teilbereichen. Außerdem wird auf Bezüge zum tatsächlichen Umwelthandeln eingegangen. Anschließend werden Konsequenzen für die Förderung des ökologischen Verantwortungsbewusstseins und des Umwelthandelns im Unternehmen aufgezeigt. Diese zielen vor allem auf den Bereich der Umweltbildung, auf die Integration individuellen Umwelthandelns in kollektive Handlungsstrategien und auf die Entwicklung einer ökologischen Konfliktkultur im Unternehmen.