gebhart/patrepeval huggingface dataset:
[Role of frozen section biopsy in the diagnosis of adnexal neoplasms]. (1993)

Three hundred and five patients undergoing exploratory laparotomy by adnexial tumors in our institution from January 1987 to October 1992 were studied. The results of the frozen sections vs permanent sections were compared. The diagnosis was concordant in 98.7% of the cases. Sensitivity was 96.9% and specificity was 99.6%. These results consagrate frozen sections as an accuracy and efficient intraoperative diagnostic form in the ovary tumoral pathology.
Effective Procedure of Bioactivity Treatment to Bearing Grade PEEK by Incorporation of Apatite Nuclei (2018)

In this study, we aimed to combine good mechanical properties of bearing grade PEEK with bioactivity for more attractive implant material. We succeeded in providing bioactivity for bearing grade PEEK by the following three steps. First, we formed micropores on bearing grade PEEK by the immersion in sulfuric acid. Second, the bearing grade PEEK plate with micropores was exposed to O2 plasma by glow discharge for providing hidrophilicity. Finally, Apatite Nuclei (AN), precursors of hydroxyapatite (HAp), was deposited on the substrate. This bioactive bearing grade PEEK was covered with HAp within 1 d immersion in SBF. It was suggested that AN were essential for providing bioactivity to bearing grade PEEK in the present method. The adhesive strength between induced HAp layer and bearing grade PEEK was obtained due to mechanical interlocking effect of micropores formed by sulfuric acid treatment. In addition, it was suggested that the combination of sulfuric acid treatment and subsequent glow discharge treatment was effective for good adhesive strength between induced HAp layer and bearing grade PEEK plate.
Salvo: Seismic imaging software for complex geologies (2000)

This report describes Salvo, a three-dimensional seismic-imaging software for complex geologies. Regions of complex geology, such as overthrusts and salt structures, can cause difficulties for many seismic-imaging algorithms used in production today. The paraxial wave equation and finite-difference methods used within Salvo can produce high-quality seismic images in these difficult regions. However this approach comes with higher computational costs which have been too expensive for standard production. Salvo uses improved numerical algorithms and methods, along with parallel computing, to produce high-quality images and to reduce the computational and the data input/output (I/O) costs. This report documents the numerical algorithms implemented for the paraxial wave equation, including absorbing boundary conditions, phase corrections, imaging conditions, phase encoding, and reduced-source migration. This report also describes I/O algorithms for large seismic data sets and images and parallelization methods used to obtain high efficiencies for both the computations and the I/O of seismic data sets. Finally, this report describes the required steps to compile, port and optimize the Salvo software, and describes the validation data sets used to help verify a working copy of Salvo.
Bactericidal activity and target preference of a piperazinyl-cross-linked ciprofloxacin dimer with Staphylococcus aureus and Escherichia coli (2006)

The dimer readily killed S. aureus and E. coli, representative gram-positive and gram-negative bacteria. In both cases the preferred target was DNA gyrase. The switch in target preference may be responsible for the greater lethality of the dimer seen with S. aureus.
[Post-parotidectomy Frey's syndrome. Treatment with botulinum toxin type A]. (2000)

The Frey's syndrome, manifest after parotid trauma, is characterized by head and neck hyperemia and abundant sweating of the hyperemic skin in response to gustatory stimuli. The use of the botulin toxin to treat the symptoms in patients with Frey's syndrome has been described in numerous studies. For some time up until now our Center has achieved excellent results using the group A botulin toxin to overcome the hypertonus of the cricopharyngeal muscle in patients who had undergone laryngectomy and were rehabilitated with voice button. We have sought to extend the use of this toxin to Frey's syndrome, a relatively frequent complication of parotidectomy. A total of 86 patients participated in the study: 41 males (47.6%) and 45 females (52.4%) ranging in age from 25 to 77 years (average age 51 years). Of these patients 7 (8.1%) had undergone post-operative radiotherapy. Of the 86 patients studied, 18 referred significant symptoms in terms of abundance and frequency. The syndrome was considered severe if the symptoms were present at each meal and if the patient indicated a significant worsening of his quality of life. Intermittent episodes were indicated by 22 patients. The remaining 46 (43.5%) did not complain of any symptoms. The exact extension of the cervicofacial gustatory sweating was evaluated using the Minor test and the involved region was divided into 1 square centimeters sections. The amount of skin surface involved ranged from 10 to 80 square centimeters. The type A neurotoxin was frozen and was reconstituted with a sterile saline solution at a final concentration of 2.5 UI/0.1 ml. The intracutaneous infiltration was performed without anesthesia, infiltrating 0.1 ml of solution, containing 2.5 UI of toxin into the center of each 1 square centimeters section. Statistical analysis was performed to evaluate the potential relationship between how long the treatment was effective, incidence of recurrence, seriousness of the crises and the following variables: age, sex, histology, cutaneous surface involved, injected dose of botulin toxin and post-operative radiotherapy. In the group of 18 patients with severe symptoms (20.9%) the benefit was immediate in all cases although the recurrence rate was 50%. The Frey's syndrome symptoms disappeared within 7 days of infiltration. In the group of 22 patients with less severe involvement (25.5%), the treatment gave positive, definitive results in 16 patients (72.7%). Those patients whose symptoms persisted were treated a second time with an infiltration of 2.5 UI per square centimeters. We feel that the use of the type A botulin toxin is the most appropriate treatment for the Frey's syndrome. In fact, such treatment offers the following advantages: it is effective within 7 days, has limited side effects, can be applied on an outpatient basis, is inexpensive and is positively considered by the patients.
Retracted: Chemoenzymatic Method for Enantioselective Synthesis of (R)‐2‐Phenylglycine and (R)‐2‐Phenylglycine Amide from Benzaldehyde and KCN Using Difference of Enzyme Affinity to the Enantiomers (2018)

Abstract In general, enzymatic and chemoenzymatic methods for asymmetric synthesis of α‐amino acids are performed using highly enantioselective enzymes. The enzymatic reactions using α‐aminonitrile as a starting material have been performed using reaction conditions apart from the chemical Strecker synthesis. We developed a new chemoenzymatic method for the asymmetric synthesis of α‐amino acids from aldehydes and KCN by performing Strecker synthesis and nitrilase reaction in the same reaction mixture. Nitrilase AY487533 that showed rather low enantioselectivity in hydrolysis of 2‐phenylglycinonitrile (2PGN) to 2‐phenylglycine (2PG) was utilized in the hydrolysis of aminonitrile formed from benzaldehyde and KCN via 2PGN by Strecker synthesis, preferentially synthesizing ( R )‐2PG with more than 95 % yield and enantiomeric excess (ee). The method was also utilized for the synthesis of ( R )‐2‐phenylglycine amide (( R )‐2PGNH 2 ) from benzaldehyde and KCN by the chemoenzymatic reaction in the presence of a mutated nitrilase AY487533W186A, which catalyzes the conversion of 2PGN to 2PGNH 2 .
A Case of Reoperation for Old Mandibular Fracture (1994)

The purpose of treatment of jaw fracture and deformities is to improve the appearance and stomatognathic function of the oral and maxi ilofacial region. Morphological examination has been performed extensively in the orthodontic field; however, objective functional assessment methods for the masticatory system are few.The patient, a 19-year-old female, was referred to us and complained of occlusal discomfort and man-dibular deviation. We performed open reduction of the malunion fracture and evaluated the stomato-gnathic function, i. e., occlusal contacts in intercuspal position and muscle contraction pattern during gum chewing, by means of medical engineering instruments pre and post operatively.
Anti-CD20 Therapy Alters the Protein Signature in Experimental Murine AIH, but Not Exclusively towards Regeneration (2021)

In conclusion, anti-CD20 therapy did not produce clinically measurable results because it triggered inflammation, as well as regeneration, at the proteomic level. This finding suggests that anti-CD20 is ineffective as a sole treatment for AIH or emAIH.
ShadowCam: Real-Time Detection of Moving Obstacles Behind A Corner For Autonomous Vehicles (2018)

Moving obstacles occluded by corners are a potential source for collisions in mobile robotics applications such as autonomous vehicles. In this paper, we address the problem of anticipating such collisions by proposing a vision-based detection algorithm for obstacles which are outside of a vehicle's direct line of sight. Our method detects shadows of obstacles hidden around corners and automatically classifies these unseen obstacles as “dynamic” or “static”. We evaluate our proposed detection algorithm on real-world corners and a large variety of simulated environments to assess generalizability in different challenging surface and lighting conditions. The mean classification accuracy on simulated data is around 80% and on real-world corners approximately 70%. Additionally, we integrate our detection system on a full-scale autonomous wheelchair and demonstrate its feasibility as an additional safety mechanism through real-world experiments. We release our real-time-capable implementation of the proposed ShadowCam algorithm and the dataset containing simulated and real-world data under an open-source license.
Using mobile phones to write in air (2011)

Numerous sensors in modern mobile phones enable a range of people-centric applications. This paper envisions a system called PhonePoint Pen that uses the in-built accelerometer in mobile phones to recognize human writing. By holding the phone like a pen, a user should be able to write short messages or draw simple diagrams in the air. The acceleration due to hand gestures can be translated into geometric strokes, and recognized as characters. We prototype the PhonePoint Pen on the Nokia N95 platform, and evaluate it through real users. Results show that English characters can be identified with an average accuracy of 91.9%, if the users conform to a few reasonable constraints. Future work is focused on refining the prototype, with the goal of offering a new user-experience that complements keyboards and touch-screens.
Toward Fast Computation of Dense Image Correspondence on the GPU (2007)

Large-scale video processing systems are needed to support human analysis of massive collections of image streams. Video, from both current small-format and future large-format camera systems, constitutes the single largest data source of the near future, dwarfing the output of all other data sources combined. A critical component to further advances in the processing and analysis of such video streams is the ability to register successive video frames into a common coordinate system at the pixel level. This capability enables further downstream processing, such as background/mover segmentation, 3D model extraction, and compression. We present here our recent work on computing these correspondences. We employ coarse-to-fine hierarchical approach, matching pixels from the domain of a source image to the domain of a target image at successively higher resolutions. Our diamond-style image hierarchy, with total pixel counts increasing by only a factor of two at each level, improves the prediction quality as we advance from level to level, and reduces potential grid artifacts in the results. We demonstrate the quality our approach on real aerial city imagery. We find that registration accuracy is generally on the order of one quarter of a pixel. We also benchmark the fundamental processing kernels on the GPU to show the promise of the approach for real-time video processing applications.
Integrin beta-3 genetic variants and risk of venous thromboembolism in colorectal cancer patients (2015)

This study identified the rs3809865 A/A genotype as an independent risk factor for VTE in CRC patients. Our findings would help identify high risk patients and would be essential for tailored anticoagulant prophylaxis.
Exploring a Brain Controlled Interface for Emotional Awareness (2012)

Emotions play an important role in human interaction, communication, coordination, and cooperation. The perception of emotional and affective state in present and past group's activities is a relevant issue since emotional awareness influence the outcome of cooperative work. While there is a growing interest in providing computational support for recognition and representation of emotions, few research efforts explore the potential of Brain Controlled Interfaces (BCI) to collect and present emotional awareness in synchronous collaborative systems. In this paper, we present an initial step in exploring how a low-cost off-the-shelf electroencephalograph (EEG) system can be used to provide emotional awareness information in synchronous collaborative editing systems.
Glutamine, but not Branched-Chain Amino Acids, Restores Intestinal Barrier Function during Activity-Based Anorexia (2019)

In conclusion, oral Gln specifically improves colonic response during ABA. These data should be further confirmed in AN patients.
CAR ROLL AND WHEEL LIFT, PROBLEM SOLVING APPROACHES (1965)

The author discusses the problem of derailment and larger hopper cars as a two step process, (1) problem definition and (2) the selection of possible solutions or alternatives. It is pointed out that not all 100-ton cars derail. Only a relative few derail and, those which do, derail at more or less predictable locations. In the rail-versus-car controversy, it is obviously not very reasonable to spend the money to overhaul every mile of railroad track, nor is it any more reasonable to condemn the 100-ton car since it is one of the major factors contributing to increased railroad business. One possible solution might be to correct the very bad areas of track where the rail joint conditions produce severe dip, and the track arrangement is such that roll is reinforced; then do enough to the car itself to make it tolerate the remaining track. A few solutions on which there has been some work during the last year or two include improvement of the track and roadbed, and control of operation of the train so that susceptible cars don't move over troublesome curves at the critical speed or under certain conditions of draft or buff. Most derailments occur with newer cars, and when substantial milage is accumulated so all contact surfaces are worked in and maximum freedom of movement is attained there is a distinctly lessened tendency toward derailment. However, work on hopper car derailments has not produced a generalized solution which is widely adopted.
Supplementary Fig. 3 from Intravenous N-Acetylcysteine to Prevent Cisplatin-Induced Hearing Loss in Children: A Nonrandomized Controlled Phase I Trial (2023)

&lt;p&gt;Supplementary Fig. 3 Change in serum glutathione concentrations following NAC infusion&lt;/p&gt;
Impaired circadian rhythm of melatonin secretion in sedated critically ill patients with severe sepsis* (2002)

The present study revealed striking abnormalities in urinary aMT6s excretion in septic ICU patients. In contrast, circadian rhythm was preserved in nonseptic ICU patients, indicating that impaired circadian melatonin secretion in septic patients is mainly related to the presence of severe sepsis and/or concomitant medication. Further investigations are required to examine the underlying pathophysiologic mechanism and the clinical implications of this finding.
Stereochemistry of bicyclo[3.2.1]octane. XV. Acetolysis of constrained cyclohexyl tosylates (1967)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStereochemistry of bicyclo[3.2.1]octane. XV. Acetolysis of constrained cyclohexyl tosylatesCharles W. Jefford, David T. Hill, and J. GunsherCite this: J. Am. Chem. Soc. 1967, 89, 26, 6881–6884Publication Date (Print):December 1, 1967Publication History Published online1 May 2002Published inissue 1 December 1967https://pubs.acs.org/doi/10.1021/ja01002a013https://doi.org/10.1021/ja01002a013research-articleACS PublicationsRequest reuse permissionsArticle Views78Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Complex Dynamics of Droplet Traffic in a Bifurcating Microfluidic Channel: Periodicity, Multistability, and Selection Rules (2010)

The binary path selection of droplets reaching a T junction is regulated by time-delayed feedback and nonlinear couplings. Such mechanisms result in complex dynamics of droplet partitioning: numerous discrete bifurcations between periodic regimes are observed. We introduce a model based on an approximation that makes this problem tractable. This allows us to derive analytical formulae that predict the occurrence of the bifurcations between consecutive regimes, establish selection rules for the period of a regime, and describe the evolutions of the period and complexity of droplet pattern in a cycle with the key parameters of the system. We discuss the validity and limitations of our model which describes semiquantitatively both numerical simulations and microfluidic experiments.
Allocation of Routinely Monitored Mixing Ratios of Nitrogen Oxides to Their Sources (2007)

In many urban areas throughout the world, the rising mean and peak levels of nitrogen oxides (NOx) are a concern. Road traffic and local industry are usually the major NOx sources in urban environments, buttheir relative contributions to the spatial distribution of the NOx volumetric mixing ratio is normally unknown. This missing piece of information is required for designing effective abatement measures to reduce ambient NOx levels. A new method for estimating the shares of which traffic and industry contribute to the mean ambient NOx mixing ratios observed in urban environments is proposed in this paper. The estimation is based on data obtained by routine air pollution monitoring, using a few assumptions aboutthe temporal emission patterns of NOx and SO2 in the area of study. A set of equations is formulated for the unknown industry and traffic contributions to the NOx mixing ratios at each monitoring site. These equations are solved using the gradient projection optimization method. The bootstrap technique is used to estimate the errors in the process. Spatial maps of the separate shares of industry and traffic in the total ambient NOx levels can be obtained where a sufficient aerial coverage of stations is available. An application of the method to the allocation of NOx mixing ratios to traffic and industrial sources in the Haifa Bay area, Israel, is demonstrated. The results are expected to be useful for future planning of traffic thoroughfares and industrial development in the area.
The role of anti-vascular endothelial growth factor (anti-VEGF) in the management of proliferative diabetic retinopathy (2018)

Diabetes is a major cause of visual impairment among working-age adults in the United States. The proliferative form of diabetic retinopathy is associated with severe vision loss (acuity <5/200). The standard treatment in proliferative diabetic retinopathy (PDR) is panretinal photocoagulation (PRP), which is effective but has established side effects such as peripheral visual-field constraints. Vascular endothelial growth factor (VEGF) is thought to drive the process of vascular proliferation. Drugs targeting VEGF (anti-VEGF) have been studied extensively in diabetic macular edema (DME), and results have shown that diabetic retinopathy regresses with anti-VEGF treatment. Recent studies show that anti-VEGF is not inferior to PRP for PDR while treatment is maintained, though recurrence rate when anti-VEGF treatment is stopped is unclear. In vitreous hemorrhage where PRP cannot be performed, use of anti-VEGF medications can treat underlying PDR and delay or reduce need for vitrectomy. Limitations of anti-VEGF treatment, however, require careful patient selection and monitoring. This review discusses recent clinical trials and guidelines for anti-VEGF use in PDR.
Statistical Characterization of the Medical Ultrasound Echo Signals (2016)

Medical ultrasound echo signals provide the basic information for obtaining the ultrasonic image in medical ultrasound technology. The statistics of the ultrasound echo signals reveals the systematic structure of the medical ultrasonic image via analyzing the corresponding statistical distributions. A novel statistical distribution, the ascending order K distribution, was proposed here to model the medical ultrasound echo signals. The ascending order K distribution was developed in light of the statistical analysis of the sequential waveforms in the echo signals. Comparison with the previous statistical distributions was made to verify the superiority of the ascending order K distribution. Further discussion showed the determination of the statistical principles for the ultrasound signals can enhance our understanding of the statistical principles of the ultrasound imaging, and thus, facilitate the optimization of the ultrasound image and the tissue identification in the ultrasound diagnosis.
Clustering of power networks: An information-theoretic perspective (2017)

An electrical power transmission system can be represented as a network with nodes and links representing buses and impedance between the buses, respectively. Decomposing a large interconnected power network into smaller loosely-coupled groups facilitates easy and flexible management of the power transmission systems by allowing secondary voltage control at regional levels and controlled islanding that aims to prevent the spreading of large-area blackouts. In this paper, we address the problem of clustering a power network into prespecified number of zones that are weakly coupled electrically by using an information-theoretic clustering algorithm. A notion of electrical similarity between electrical buses is developed, where any two buses are considered similar, if reactive perturbations at these buses have a similar effect on the entire network. A thorough theoretical justification of the use of the proposed clustering approach is provided along with the results of our methodology for IEEE test systems.