gebhart/patrepeval huggingface dataset:
A New Route to Glycosyl Phosphates (1962)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA New Route to Glycosyl PhosphatesDonald L. MacDonaldCite this: J. Org. Chem. 1962, 27, 3, 1107–1109Publication Date (Print):March 1, 1962Publication History Published online1 May 2002Published inissue 1 March 1962https://pubs.acs.org/doi/10.1021/jo01050a552https://doi.org/10.1021/jo01050a552research-articleACS PublicationsRequest reuse permissionsArticle Views452Altmetric-Citations103LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
2P1-G22 Development of a Digital Pen Using Inertial Navigation Method : Accuracy improvement by offset correction (2008)

A digital pen using three dimensional instrumentation technology by the inertial navigation method is developed. This paper describes the estimation method for sensor offset aiming at accurate pen tip trajectory and the verification of the effect.
Supplementary Figure 1 from Dendritic Cells in Tumor-Associated Tertiary Lymphoid Structures Signal a Th1 Cytotoxic Immune Contexture and License the Positive Prognostic Value of Infiltrating CD8<sup>+</sup> T Cells (2023)

&lt;p&gt;PDF file - 200K, Twelve-color analysis of the immune cell populations in freshly resected tumors.&lt;/p&gt;
Semantics (1951)

Through the Forum, I should like to add a postscript to my article “Physicists and the English Language” (Physics Today, February 1950). The postscript consists of a bibliography, comments on it, and a suggestion that emerges from it.
Ring-Opening Polymerization of 1,1,2,2-Tetramethyl-1,2-disilacyclopentane via Palladium Complex-Catalyzed Si-Si Bond Metathesis (1995)

Abstract Ring-opening metathesis polymerization of 1,1,2,2-tetramethyl-1,2-disilacyclopentane was found to proceed in the presence of catalytic amounts of a Pd complex (PdCl2(dppb) or PbCl2(dbpb)) and 1,2-difluoro-1,1,2,2-tetramethyldisilane to effectively give a high molecular weight polymer (Mw &amp;gt; 3 × 105).
Full-field high-resolution terahertz imaging based on a high-resistance silicon solid immersion lens (2022)

The spatial resolution of the direct imaging system depends on the wavelength and the numerical aperture. In the terahertz (THz) waveband, the wavelength is relatively large, and the higher numerical aperture of the imaging system usually promises the possibility of achieving higher spatial resolution. Solid immersion technique is an effective method to expand the numerical aperture. We design and fabricate a hemisphere lens with high-resistance silicon to achieve the effect of solid immersion, and obtain full-field, high-resolution focal-plane imaging. The characteristics of the direct refraction imaging and the secondary reflection imaging are analyzed by ray-tracing calculations. And the field curvature of the equivalent object plane and the spot diagram on the vertical image plane of the lens are quantifiably evaluated. It is shown that the secondary reflection imaging can effectively reduce the geometric distortion and achieve more ideal imaging quality. The method of blocking different regions before and after the solid immersion lens is proposed to obtain a clear magnified image of a two-dimensional grating with the period of 300 µm. This method provides a powerful tool for THz full-field microscopic imaging.
Hate is not Binary (2017)

Over the past few years, online bullying and aggression have become increasingly prominent, and manifested in many different forms on social media. However, there is little work analyzing the characteristics of abusive users and what distinguishes them from typical social media users. In this paper, we start addressing this gap by analyzing tweets containing a great amount of abusiveness. We focus on a Twitter dataset revolving around the Gamergate controversy, which led to many incidents of cyberbullying and cyberaggression on various gaming and social media platforms. We study the properties of the users tweeting about Gamergate, the content they post, and the differences in their behavior compared to typical Twitter users.
Analysis of vasculature for liver surgical planning (2002)

For liver surgical planning, the structure and morphology of the hepatic vessels and their relationship to tumors are of major interest. To achieve a fast and robust assistance with optimal quantitative and visual information, we present methods for a geometrical and structural analysis of vessel systems. Starting from the raw image data a sequence of image processing steps has to be carried out until a three-dimensional representation of the relevant anatomic and pathologic structures is generated. Based on computed tomography (CT) scans, the following steps are performed. 1) The volume data is preprocessed and the vessels are segmented. 2) The skeleton of the vessels is determined and transformed into a graph enabling a geometrical and structural shape analysis. Using this information the different intrahepatic vessel systems are identified automatically. 3) Based on the structural analysis of the branches of the portal vein, their vascular territories are approximated with different methods. These methods are compared and validated anatomically by means of corrosion casts of human livers. 4) Vessels are visualized with graphics primitives fitted to the skeleton to provide smooth visualizations without aliasing artifacts. The image analysis techniques have been evaluated in the clinical environment and have been used in more than 170 cases so far to plan interventions and transplantations.
The multicomponent characterization of Shuanghe decoction by dimension-enhanced data-independent HDMSE: Focusing on the performance comparison between MSE and HDMSE (2021)

The co-elution, pervasive isomers, and frequently occurring in-source fragmentation definitely hinder the comprehensive characterization of the multiple components from traditional Chinese medicine (TCM) by liquid chromatography/mass spectrometry. Herein, a dimension-enhanced strategy, by utilizing an ion mobility quadrupole time-of-flight mass spectrometer coupled to ultra-high performance liquid chromatography (UHPLC/IM-QTOF-MS) with the ability of offering four-dimensional information (retention time, Rt; drift time or collision cross section, CCS; accurate mass of precursors; and accurate MS2 product ions), is presented. Shuanghe Decoction (SHD) is a classic tonifying formula composed of nine herbs, however, little is known to its chemical complexity, hitherto. Good chromatographic separation was achieved on an HSS T3 column, and by the Vion™ IMS-QTOF high-resolution mass spectrometer, data-independent MSE and High-Definition MSE (HDMSE) in both the negative and positive electrospray ionization modes were employed for acquiring the collision-induced dissociation-MS2 data. A self-built database, including 642 known compounds, was established, which assisted to perform the automated peak annotation by UNIFI™. By reference to 55 compounds, totally 236 components were identified or tentatively characterized from SHD with 4D data recorded. The combination of negative and positive modes could yield more information complementary to structural elucidation. Compared with the conventional MSE, HDMSE exhibit of merits in the provision of CCS, better separation and detection those easily co-eluting components, and reduction of the false positives in the identification results. Conclusively, the combination of HDMSE acquisition, in-house library, and UNIFI-facilitated automated peak annotation, renders a potent approach dedicated to deconvoluting the chemical composition of complex systems like TCM formulae.
Soliton transmission using periodic dispersion compensation (1997)

We examine the behavior of solitons in optical fibers where the dispersion is alternated between the normal and anomalous regimes. The periodic nature of the system strongly modifies the shape of the stable soliton (solitary wave) pulses, and increases their energy when compared with solitons in equivalent uniform fibers. Power enhancement factors of up to 70 are numerically observed. This leads to both an increased signal-to-noise ratio (SNR) at the receiver and reduced Gordon-Haus timing jitter. The interaction between pairs of isolated pulses is examined. We also examine implementations including periodic amplification, and show that the energy scalings introduced by the amplification and the dispersion management are independent provided that the periods of the two processes are dissimilar. We show that there is an optimum dispersion compensation ratio which minimizes the received Gordon-Haus jitter. A diagrammatic technique is presented for estimating the performance of dispersion compensated soliton transmission systems.
Development of a CDK10/CycM in vitro Kinase Screening Assay and Identification of First Small-Molecule Inhibitors (2020)

Cyclin-dependent kinases (CDKs) constitute a family of 20 serine/threonine protein kinases that play pivotal roles in the regulation of numerous important molecular and cellular processes. CDKs have long been considered promising therapeutic targets in a variety of pathologies, and the recent therapeutic success of CDK4/6 inhibitors in breast cancers has renewed interest in their therapeutic potential. Small-molecule inhibitors have been identified for every human CDK, except for CDK10. The only recent discovery of an activating cyclin (CycM) for CDK10 enabled us to identify its first phosphorylation substrates and gain insights into its biological functions. Yet, our knowledge of this kinase remains incomplete, despite it being the only member of its family that causes severe human developmental syndromes, when mutated either on the cyclin or the CDK moiety. CDK10 small-molecule inhibitors would be useful in exploring the functions of this kinase and gauging its potential as a therapeutic target for some cancers. Here, we report the identification of an optimized peptide phosphorylation substrate of CDK10/CycM and the development of the first homogeneous, miniaturized CDK10/CycM <i>in vitro</i> kinase assay. We reveal the ability of known CDK inhibitors, among which clinically tested SNS-032, riviciclib, flavopiridol, dinaciclib, AZD4573 and AT7519, to potently inhibit CDK10/CycM. We also show that NVP-2, a strong, remarkably selective CDK9 inhibitor is an equally potent CDK10/CycM inhibitor. Finally, we validate this kinase assay for applications in high-throughput screening campaigns to discover new, original CDK10 inhibitors.
A Novel Energy Efficient Broadcast Leader Election (2013)

We introduce a new algorithm to achieve a distributed leader election in a broadcast channel that is more efficient than the classic Part-and-Try algorithm. The algorithm has the advantage of having a reduced overhead log logN rather than log N. More importantly, the algorithm has a greatly reduced energy consumption since it requires O(N <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1=k</sup> ) burst transmissions instead of O(N=k), per election, k being a parameter depending on the physical properties of the medium of communication. The algorithm has interesting potential applications in cognitive wireless networking.
Peritoneoscopy in a developing country. (1980)

Peritoneoscopy in medical cases remains largely unpopular in the USA and the UK. In many developing countries there is often a heavy demand on medical facilities and the rapid diagnosis of intra-abdominal problems is of major importance. We present a series of 193 patients in whom peritoneoscopy was carried out during a 2 1/2-year period. Eighty-six per cent (166) of examinations yielded information of positive diagnostic value. The most common diagnoses were hepatocellular carcinoma, liver cirrhosis, bilharzial fibrosis and peritoneal tuberculosis. The peritoneoscopic appearances in the various lesions are illustrated and discussed. Peritoneoscopy is a safe procedure and its value in a developing country is great, both in terms of economy of man-hours employed and, more particularly, of diagnostic yield.
Aqua-Net: An underwater sensor network architecture: Design, implementation, and initial testing (2009)

Underwater sensor networks (UWSNs) have emerged as a powerful technique for a wide range of aquatic applications. New challenges require novel research at every layer of the protocol stack. To efficiently compare various design, algorithms, and protocols, there is a pressing need for a generic architecture for underwater sensor networks. In this paper, we present such an architecture, called Aqua-Set, for various underwater solutions and applications. Aqua-Net follows a layered structure and meanwhile could support cross-layer optimization. It is flexible and easy to use. We have implemented several protocols in Aqua-Net and tested in a lab environment. Specifically, in this paper we present the design, implementation, and testing of a MAC protocol, called UW-Aloha, as a case study. The initial results show that our analysis, and lab testing match very well. We consider Aqua-Net a groundwork and valuable tool for future advances of the underwater sensor network research.
63.2: Single Layer Multi‐Color Electrowetting Display by Using Ink Jet Printing Technology and Fluid Motion Prediction with Simulation (2010)

Abstract For outdoor multimedia device, electrowetting display (EWD) is one of the potential technologies. In this paper, we evaluated the single layer multi‐color EW device by using various colored oils without adopting color filter. The oils were dosed into the pixel by using ink‐jet printing (UP) technique. for colored oils, in order to improve the color saturation of EWD panel, we used mixed solvent to increase the solubility of dyes. Then, by using UP technique, a single layer multi‐color EW device was successfully fabricated and the optical property had been evaluated. Also, to improve the reliability of fluid motion, a simulation named FLUENT was first adopted to predict and realize the fluid behavior under different electric force.
ChemInform Abstract: PHASE TRANSITIONS IN THE SYSTEMS TRIRUBIDIUM TRIOXOTRIFLUOROMOLYBDATE‐TRIRUBIDIUM HEXAFLUOROFERRATE AND TRIAMMONIUM HEXAFLUOROFERRATE‐TRIRUBIDIUM HEXAFLUOROFERRATE (1982)

Abstract In den Titelsystemen lassen sich ausgedehnte Mischkristallbereiche mit einer dem (NH 4 ) 3 F eFÖ verwandten Struktur nachweisen.
Optimal Control Problem for a Modified Novikov Equation with Dissipation (2014)

This paper investigate the optimal control problem for a modified Novikov equation with dissipation. The existence and uniqueness of regular local solution to the corresponding initial boundary value problem is guaranteed by the Faedo-Galerkin method. A critical estimate of the solution is obtained. Finally, the existence of an optimal solution to the control problem is proved.
Vacuum-dressed cavity magnetotransport of a two-dimensional electron gas (2018)

We present a theory predicting how the linear magnetotransport of a two-dimensional (2D) electron gas is modified by a passive electromagnetic cavity resonator where no real photons are injected nor created. For a cavity photon mode with in-plane linear polarization, the dc bulk magnetoresistivity of the 2D electron gas is anisotropic. In the regime of high filling factors of the Landau levels, the envelope of the Shubnikov--de Haas oscillations is profoundly modified and the resistivity can be increased or reduced depending on the system parameters. In the limit of low magnetic fields, the resistivity along the cavity-mode polarization direction is enhanced in the ultrastrong light-matter coupling regime. Our work shows the crucial role of virtual polariton excitations in controlling the dc charge transport properties of cavity-embedded systems.
Optimization of an implantable coated wire glucose sensor (1986)

An effective glucose sensor should have a short response time and show a strong linear relationship with concentration changes. This paper describes the methods used in an optimization experiment designed to minimize the response time and maximize the coated wire glucose sensor output (voltage or current for glucose concentrations ranging from 40 to 200 mg%). The sensor used for the experiments was a coated wire type. The object was to find the optimum membrane composition performance in relation to different glucose solution concentrations. Four experimental designs were used to analyse the effects of Aliquat: decanol (vol%), glucose salt concentration, and polymer: solvent ratio on the response time and voltage or current differences. Regression models for response time and output were used to establish the optimum experimental conditions. These models were calculated using the statistical analysis system (SAS) general linear model (GLM) procedure. Both polarographic and potentiometric models were used to determine the sensitivity of the sensor. The coated wire sensor developed during the present study had a response time of about one minute, a marked improvement over earlier designs. In addition, it yielded reproducibile voltage or current differences with changes in glucose concentration.
Identification of an Exon 4-Deletion Variant of Epidermal Growth Factor Receptor with Increased Metastasis-Promoting Capacity (2011)

Several types of epidermal growth factor receptor (EGFR) gene alternations have been observed in human tumors. Here we present a novel EGFR variant with aberrant splicing of exon 4 (named as de4 EGFR). Variant-specific polymerase chain reaction showed that de4 EGFR was expressed in some glioma (4/40), prostate cancer (3/11), and ovarian cancer (3/9) tissues but not in tissues adjacent to tumors or normal tissues. de4 EGFR displayed an enhanced transformation and a higher metastasis-promoting capacity in comparison to wild-type EGFR. With minimal EGF-binding activity, de4 EGFR underwent ligand-independent autophosphorylation and self-dimerization. Moreover, in serum-starved condition, de4 EGFR expression in U87 MG cells significantly upregulated the extracellular signal-regulated kinase and AKT phosphorylation and expression of JUN and Src. Importantly, E-cadherin expression was barely detectable in the U87 MG cells expressing de4 EGFR and restored expression of E-cadherin in these cells inhibited their metastatic behaviors. Taken together, we identified a novel EGFR variant with increased metastasis-promoting activity that may become a promising new target for cancer therapy.
Cell Polarity and PIN Protein Positioning in Arabidopsis Require STEROL METHYLTRANSFERASE1 Function (2003)

Plants have many polarized cell types, but relatively little is known about the mechanisms that establish polarity. The orc mutant was identified originally by defects in root patterning, and positional cloning revealed that the affected gene encodes STEROL METHYLTRANSFERASE1, which is required for the appropriate synthesis and composition of major membrane sterols. smt1(orc) mutants displayed several conspicuous cell polarity defects. Columella root cap cells revealed perturbed polar positioning of different organelles, and in the smt1(orc) root epidermis, polar initiation of root hairs was more randomized. Polar auxin transport and expression of the auxin reporter DR5-beta-glucuronidase were aberrant in smt1(orc). Patterning defects in smt1(orc) resembled those observed in mutants of the PIN gene family of putative auxin efflux transporters. Consistently, the membrane localization of the PIN1 and PIN3 proteins was disturbed in smt1(orc), whereas polar positioning of the influx carrier AUX1 appeared normal. Our results suggest that balanced sterol composition is a major requirement for cell polarity and auxin efflux in Arabidopsis.
Uranium(VI) sorption onto kaolinite in the presence and absence of humic acid (2006)

We studied the U(VI) sorption onto kaolinite in batch experiments in the absence and presence of humic acid (HA) under different experimental conditions: [U] 0 = 1 × 10 -6 M or 1 × 10 -5 M, [HA] 0 =10 or 50 mg/L, I =0.1 M or 0.01 M NaClO 4 , pH=3–10, CO 2 or N 2 atmosphere. The study showed that the U(VI) sorption onto kaolinite is influenced by pH, CO 2 and HA presence. In the absence of CO 2 , the U(VI) uptake increases with increasing pH value up to pH 6. Above pH 6 it remains unchanged. Because of the formation of negatively charged uranyl carbonate complexes, the decrease in the U(VI) sorption onto the negative surface of kaolinite was observed above pH 8 in the presence of CO 2 . In presence of HA, the adsorption of U(VI) closely follows the adsorption of HA. In the acidic pH range the U(VI) uptake is enhanced compared to the system without HA due to the formation of additional binding sites for U(VI) coming from HA adsorbed onto kaolinite. The formation of aqueous uranyl-humate complexes reduces the U(VI) sorption in the near neutral pH range. The enhancement of the U(VI) concentration from 1 × 10 -6 M to 1 × 10 -5 M results in the shift of the sorption pH edge by one pH unit to higher pH values. The ionic strength has only a slight influence on the U(VI) sorption onto kaolinite, whereas the HA sorption shows a dependence on the ionic strength.
Relation between Soil Properties and the Erodibility of Masa Soils (Granitic Soils) (1985)

Erosion experiments were carried out under laboratory conditions to determine the index of erodibility of Masa soils. Fifteen soil samples were collected in Kyushu. They had a low clay and silt content but a high sand content. Simple regression analysis was used to relate the amount of soil loss to the physical and chemical properties, including mechanical composition, clay ratio, aggregate stability, dispersion ratio, and pH. Among these parameters, only the mechanical composition gave a correlation significant at 1%. The content of 2–20 μm particles showed the highest and positive correlation coefficient (r=0.884**) with the amount of soil loss, followed by the content of 2–53 μm (r=0.867**) and <53 μm (r=0.857**) particles, while the content of 200–2,000 μm particles showed a negative correlation (r=−0.818* *). The content of 2–20, 2–53, or <53 μm particles was proposed as an index of erodibility of Masa soils. Preferential erosion of silt-size particles is most probable.
Syntheses of Silver Nanoparticles in the Matrices of Block and Graft Copolymers and Polymer‐Inorganic Hybrid in Aqueous Solutions (2012)

Abstract In the present work we have synthesized two‐component block‐ and graft copolymers MOPEO‐ b ‐PAAm, PAAm‐ b ‐PEO‐ b ‐PAAm and PVA‐ g ‐PAAm comprised methoxypoly(ethylene oxide), poly(ethylene oxide) or poly(vinyl alcohol) and chemically complementary polyacrylamide and also the grafted polymer‐inorganic hybrid SiO 2 ‐ g ‐PAAm based on monodispersed silica nanoparticles. These copolymers we used as special matrices in the process of borohydride reduction of Ag+ ions. It was established the influence of chemical nature, molecular architecture and concentration of the matrices and the content of silver nitrate on some reaction parameters, size and stability of Ag‐nanoparticles in aqueous solutions.