gebhart/patrepeval huggingface dataset:
Co-locating services in IoT systems to minimize the communication energy cost (2014)

Ubiquitous sensing and actuating devices are now everywhere in our living environment as part of the global cyber–physical ecosystem. Sensing and actuating capabilities can be modeled as services to compose intelligent Internet of Things (IoT) applications. An issue for perpetually running and managing these IoT devices is the energy cost. One energy saving strategy is to co-locate several services on one device in order to reduce the computing and communication energy. In this paper, we propose a service merging strategy for mapping and co-locating multiple services on devices. In a multi-hop network, the service co-location problem is formulated as a quadratic programming problem. We show a reduction method that reduces it to the integer programming problem. In a single hop network, the service co-location problem can be modeled as the Maximum Weighted Independent Set (MWIS) problem. We show the algorithm to transform a service flow to a co-location graph, then use known heuristic algorithms to find the maximum independent set which is the basis for making service co-location decisions. The performance of different co-location algorithms are evaluated by simulation in this paper.
H<inf>&#x221E;</inf> control for a smart micro-positioning system with an analytical model for the output of the inverse compensation (2015)

An experimental study was carried out on a piezoelectric actuator in order to explore the benefits of a mathematical formula [1], that describes the output of the inverse compensation when an inverse Prandtl-Ishlinskii hysteresis model is applied as a feedforward compensator. The inverse Prandtl-Ishlinskii was first formulated and applied for compensation of hysteresis nonlinearities of a piezoelectric actuator. The theoretical formula was afterwards employed to construct an H <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">∞</inf> feedback control. The controller was calculated and applied to the piezoelectric actuator with the inverse feedforward model. The experimental results verify the effectiveness of the controller and the benefits that the theoretical formula of the inverse compensation can contribute.
The Ophthalmic Branch of the Gutenberg Health Study: Study Design, Cohort Profile and Self-Reported Diseases (2015)

The GHS is the most extensive dataset of ophthalmic diseases and conditions and their risk factors in Germany and one of the largest cohorts worldwide. This dataset will provide new insight in the epidemiology of ophthalmic diseases and related medical specialties.
Hyponatremia among Runners in the Boston Marathon (2005)

Hyponatremia occurs in a substantial fraction of nonelite marathon runners and can be severe. Considerable weight gain while running, a long racing time, and body-mass-index extremes were associated with hyponatremia, whereas female sex, composition of fluids ingested, and use of nonsteroidal antiinflammatory drugs were not.
Subtype-Selective N-Methyl-d-aspartate Receptor Antagonists:  Synthesis and Biological Evaluation of 1-(Arylalkynyl)-4-benzylpiperidines (1999)

4-[4-(4-Benzylpiperidin-1-yl)but-1-ynyl]phenol (8) and 4-[3-(4-benzylpiperidin-1-yl)prop-1-ynyl]phenol (9) are potent NR1A/2B receptor antagonists (IC(50) values 0.17 and 0.10 microM, respectively). Administered intraperitoneally, they both potentiated the activity of L-DOPA in the unilaterally 6-hydroxydopamine-lesioned (6-OHDA) rat, a model of Parkinson's disease. However, compound 9 was not active orally, likely due to rapid first-pass metabolism of the phenol moiety. The phenol was replaced by several bicyclic heterocyclic systems containing an NH group to function as a H-bond donor in the hope that these would be less likely to undergo rapid metabolism. In general, indoles, indazoles, benzotriazoles, indolones, and isatins gave analogues with weaker NR1A/2B activity than the parent phenols, while benzimidazolones and benzimidazolinones gave equipotent or more potent analogues. The preference for a para arrangement between the H-bond donor and the linking acetylene moiety was confirmed, and a propyne link was preferred over a butyne link. Substitution on the benzyl group or a 4-hydroxyl group on the piperidine had little effect on NR1A/2B potency; however, 4-hydroxypiperidines demonstrated slightly improved selectivity for NR1A/2B receptors versus alpha-1 adrenergic and dopamine D2 receptor affinity. From this study, 5-[3-(4-benzylpiperidin-1-yl)prop-1-ynyl]-1, 3-dihydrobenzoimidazol-2-one (46b) was identified as a very potent, selective NR1A/2B receptor antagonist (IC(50) value 0.0053 microM). After oral administration at 10 and 30 mg/kg, 46b potentiated the effects of L-DOPA in the 6-OHDA-lesioned rat and seemed to have improved oral bioavailability but lower brain penetration compared to phenol 9.
[A boy with occipital lobe epilepsy showing prolonged QTc in the ictal ECG]. (2002)

We report a 9-year-old boy with occipital lobe epilepsy who showed a prolonged QTc on the ictal electrocardiogram (ECG). He complained of sudden onset of blindness accompanied with vomiting and headache. Since ECG revealed a prolonged QTc, he was transferred to our pediatric emergency center. Occipital spike and slow wave complexes on the electroencephalogram (EEG) suggested the diagnosis of occipital lobe epilepsy. Administration of carbamazepine (190 mg) resulted in the disappearance of the blindness and abnormal waves on EEG. This is the first report to describe the occurrence of prolonged QTc during seizures of occipital lobe epilepsy. Because of the high risk of life-threatening ventricular arrhythmia induced by prolongation of QTc such as torsades de pointes, attention should be paid to the ECG findings in patients with occipital lobe epilepsy.
The NBS alloy data center: Description of index to the literature (1970)

Computerized listings of 10,000 research papers, indexed at the Alloy Data Center, are now being made available in two forms. In the first, the Permuted Materials Index, all records are arranged alphabetically by chemical symbol. Records referring to alloys or compounds are listed under each of the constituent elements. In the second, the Author Index, all papers are listed alphabetically by first author in three groupings: the first, the NMR papers; the second, the soft x-ray papers; and the third, a broad group of papers that have been of general interest to the Alloy Physics Section. The magnetic tape on which the indexed file is stored will be made available at a future date.
Constitutive Internalization of the Leucine-rich G Protein-coupled Receptor-5 (LGR5) to the Trans-Golgi Network (2013)

LGR5 is a Wnt pathway associated G protein-coupled receptor (GPCR) that serves as a molecular determinant of stem cells in numerous tissues including the intestine, stomach, hair follicle, eye, and mammary gland. Despite its importance as a marker for this critical niche, little is known about LGR5 signaling nor the biochemical mechanisms and receptor determinants that regulate LGR5 membrane expression and intracellular trafficking. Most importantly, in cells LGR5 is predominantly intracellular, yet the mechanisms underlying this behavior have not been determined. In this work we elucidate a precise trafficking program for LGR5 and identify the motif at its C terminus that is responsible for the observed constitutive internalization. We show that this process is dependent upon dynamin GTPase activity and find that wild-type full-length LGR5 rapidly internalizes into EEA1- and Rab5-positive endosomes. However, LGR5 fails to rapidly recycle to the plasmid membrane through Rab4-positive vesicles, as is common for other GPCRs. Rather, internalized LGR5 transits through Rab7- and Rab9-positive vesicles, co-localizes in vesicles with Vps26, a retromer complex component that regulates retrograde trafficking to the trans-Golgi network (TGN) and reaches a steady-state distribution in the TGN within 2 h. Using mutagenesis, particularly of putative phosphorylation sites, we show that the amino acid pair, serine 861 and 864, is the principal C-tail determinant that mediates LGR5 constitutive internalization. The constitutive internalization of LGR5 to the TGN suggests the existence of novel biochemical roles for its Wnt pathway related, but ill defined signaling program.
Potential safety benefits of lane departure warning and prevention systems in the U.S. vehicle fleet (2015)

Road departures account for nearly one-third of all fatal crashes. Lane departure warning (LDW) and lane departure prevention (LDP) have the potential to mitigate the number of crashes and fatalities that result from road departure crashes. The objective of this study was to predict the effectiveness of LDW and LDP in preventing road departure crashes if all vehicles in departure crashes in the U.S. fleet were equipped with either system. A set of 478 road departure crashes extracted from NASS/CDS 2012 were used to formulate a simulation case set. Each of these crashes were than simulated with and without LDW and LDP systems. The LDW system was assumed to alert the driver at the instance the leading wheel touched the lane marking. A steering-based LDP system was assumed to operate in conjunction with LDW (i.e. by alerting the driver of a lane departure) and directly modulate steering wheel angle at the instance the leading wheel touched the lane marking. Four hypothetical LDP designs were evaluated, using typical evasive maneuvering behavior from a lane departure, to be representative of “light”, “moderate”, “aggressive”, and “autonomous” steering. The LDW system was estimated to reduce the number of crashes by 26.1% and the number of seriously injured drivers by 20.7%. In contrast, the light steering to aggressive steering LDP systems were estimated to reduce the number of crashes by 32.7% to 37.3% and the number of seriously injured drivers by 26.1% to 31.2%. The LDP system with autonomous driving characteristics were estimated to reduce the number of crashes by 51.0% and the number of serious injuries by 45.9%. This study shows that LDW and LDP could mitigate a large proportion of crashes and injuries in lane departure crashes. This paper is directly relevant to the design and evaluation of LDW and LDP systems.
Comparison of five clustering algorithms to classify phytoplankton from flow cytometry data (2001)

The adaptive distances algorithm was superior in use to the clustering algorithms against which it was tested, but the problem of automatic determination of the number of clusters remains to be addressed.
Inpatient Administration of Alpha-1-Adrenergic Receptor Blocking Agents Reduces Mortality in Male COVID-19 Patients (2022)

Apha-1-adrenergic receptor antagonists (α<sub>1</sub>-blockers) can suppress pro-inflammatory cytokines, thereby potentially improving outcomes among patients with COVID-19. Accordingly, we evaluated the association between α<sub>1</sub>-blocker exposure (before or during hospitalization) and COVID-19 in-hospital mortality. We identified 2,627 men aged 45 or older who were admitted to Mount Sinai hospitals with COVID-19 between February 24 and May 31, 2020, in New York. Men exposed to α<sub>1</sub>-blockers (<i>N</i> = 436) were older (median age 73 vs. 64 years, <i>P</i> < 0.001) and more likely to have comorbidities than unexposed men (<i>N</i> = 2,191). Overall, 777 (29.6%) patients died in hospital, and 1,850 (70.4%) were discharged. Notably, we found that α<sub>1</sub>-blocker exposure was independently associated with improved in-hospital mortality in a multivariable logistic analysis (OR 0.699; 95% CI, 0.498-0.982; <i>P</i> = 0.039) after adjusting for patient demographics, comorbidities, and baseline vitals and labs. The protective effect of α<sub>1</sub>-blockers was stronger among patients with documented inpatient exposure to α<sub>1</sub>-blockers (OR 0.624; 95% CI 0.431-0.903; <i>P</i> = 0.012). Finally, age-stratified analyses suggested variable benefit from inpatient α<sub>1</sub>-blocker across age groups: Age 45-65 OR 0.483, 95% CI 0.216-1.081 (<i>P</i> = 0.077); Age 55-75 OR 0.535, 95% CI 0.323-0.885 (<i>P</i> = 0.015); Age 65-89 OR 0.727, 95% CI 0.484-1.092 (<i>P</i> = 0.124). Taken together, clinical trials to assess the therapeutic value of α<sub>1</sub>-blockers for COVID-19 complications are warranted.
hemoglobin concentration? the lower limit of normal of the blood is (2009)

Those students that had considered leaving frequently described how a combination of diverse factors accumulated to lead to them contemplating leaving their programme. Strategies to reduce attrition in healthcare students need to consider the student lifecycle from recruitment to graduation, to set reasonable student expectations and ensure that a career within healthcare is both desired and valued.
Exploiting Instruction Set Encoding for Aging-Aware Microprocessor Design (2015)

Microprocessors fabricated at nanoscale nodes are exposed to accelerated transistor aging due to bias temperature instability and hot carrier injection. As a result, device delays increase over time, reducing the mean time to failure (MTTF) and hence lifetime of the processor. To address this challenge, many (micro)-architectural techniques target the execution stage of the instruction pipeline, as this one is typically most critical. However, also the decoding stages can become aging critical and limit the microprocessor lifetime, as we will show in this work. Therefore, we propose a novel aging-aware instruction set-encoding methodology (ArISE) that improves the instruction encoding iteratively using a heuristic algorithm. In addition, the switching activities of the affected memory elements are considered in order to co-optimize lifetime and energy efficiency. Our experimental results show that MTTF of the decoding stages can be improved by 2.3× with negligible implementation costs.
Growth and SAW Properties of (Ba2-xSrx)TiSi2O8 Crystals (1981)

Part of the phase diagram of a (Ba 2- x Sr x )TiSi 2 O 8 system is demonstrated and then (Ba 2- x Sr x )TiSi 2 O 8 ( x ≤1.0) single crystals are grown by the Czochralski (CZ) technique and the edge-defined film-fed growth (EFG) technique. The crystal composition, particularly the Sr concentration, of a CZ grown crystal varies according to the normal freezing distribution. The Sr concentration of an EFG grown crystal is almost constant. The excellent SAW properties; low temperature coefficients of delay and high electromechanical coupling factors of the grown crystals are also described.
Effect of primer progesterone in oocyte quality and in vitro embryo production of Nelore cattle (2014)

The objectives of this study were to characterize follicle population, quality and number of oocytes recovered and in vitro embryo production in pre-pubertal Nelore heifers previously exposed to progesterone (P4). The experimental design included 42 Nelore females, distributed into 4 experimental groups, as follows: PP-P4-24d- pre-pubertal heifers undergoing (OPU) previously exposed to P4 (CIDR®, Zoetis) for 24 days n=11); PP-P4-7d– pre-pubertal heifers undergoing OPU previously exposed to P4 for 7 days (n=11); PP – pre-pubertal heifers undergoing OPU without previous P4 priming (Negative Control, n=10); and VC – mature cycling cows undergoing OPU previously exposed to P4 for 7 days ( n=10). On D0, heifers in PP-P4-24d received a CIDR®, which was removed on D7 of the protocol. These same animals received another P4 device on Day 14. Animals in groups PP-P4-7 d and VC received a P4 device for 7 days (Day 24 to 31). All females received intramuscularly 2.0 mg of estradiol benzoate (BE; Gonadiol, Schering Plough) on day 24 of the protocol. All devices were removed previously follicular aspiration (Day 31). At the time of OPU, ovaries were examined by ultrasonography to estimate follicular population. Data was analyzed with the procedure GLIMMIX of SAS and shown as means ± SEM. Means were assumed different when P<0.05. The number of recruited follicles (43.3±2.0 vs 58.9±2.4 vs 58.1±2.4 vs 58.2±2.7, P<0.001), number of total oocytes (25.9±1.5 vs 37.1±1.9 vs 41.4±2.3 vs 33.1±2.0, P<0.001), and number of viable oocytes (15.9±1.2 vs 26.1±1.6 vs 30.8±1.8 vs 22.5±1.7, P<0.001) was less in PP-P4-24d than in PP-P4-7d, PP, and VC, respectively. However, there were no differences among groups in terms of total embryos produced per OPU session (4.7±0.7 vs 4.4±0.7 vs 5.1±0.7 vs 4±0.7, respectively for PP-P4-24d, PP-P4-7d, PP, and VC, P=0.7). In addition, the embryo rate (number of embryos/number of viable oocytes) was lower (P<0,001) in PP-P4-7d (18.1%) and PP (15.3%) in comparison to PP-P4-24d (29.7%) and VC (25.9%) groups. As a conclusion, prepubertal Nelore heifers exposed to 24 days of progesterone previously to the OPU presented lower number of follicles and recovered oocytes but higher in vitro embryo production rates.
Die Synthese von 5α‐Stigmastadien‐(7.25)ol‐(3β) (1970)

Abstract Das Titelsterin ( 1a ) wird aus 3β‐Acetoxy‐22.23‐dinor‐5α‐cholen‐(7)‐aldehyd ( 3 ) über den homologen Aldehyd 5 , den Ketoester 9 und das Abbau‐Ketolacetat 2b des Naturstoffs nach bekannten Methoden synthetisch dargestellt.
Skillful manipulation of virtual objects: Implementation of juggling in a virtual environment (2012)

This paper describes our study on skillful object manipulation in virtual environments. The study deals with juggling balls and aims to implement a virtual environment in which juggling operations similar to those in the real world are possible. The juggling task requires precise ball handling and quick hand motion and the virtual environment must respond to the user accurately and quickly. This paper focuses on the implementation of such a virtual environment. A visual display based on immersive projection technology was employed to cover a wide vertical field of view and computation algorithm for interaction was improved to simulate fast motion collision. In addition, auditory feedback was introduced to compensate for the lack of force and tactile sensations. The prototype environment was evaluated through experiments using subjects, and it was proved that users can perform two-ball juggling in the virtual environment, although their performance is poorer than that in the real world, and that auditory contact feedback improves the performance.
Influence of fuel mixture on spray formation in die sel processes (2010)

In this measurement series the spray behavior of di fferent fuels available on the market and canola oi l was carried out. It was clearly visible that high boiling components, like fatty acid methyl ester, the canol a oil itself or gas to liquid additives, increase the maximum penet ration depth of the liquid fuel phase
Performances and Characteristics of DIGRank, Ranking in the Incomplete Networks (2011)

Page Rank has been widely used in ranking retrieval results on the web, finding the top influential papers in citation networks or detecting valuable users in online social networks. However, in practice, it is usually hard to obtain a complete structure of any above networks to rank nodes. Thus, some researchers have begun to explore how to get estimated ranks efficiently without acquiring the whole network. They have proposed some approximating methods, however, it is difficult to determine which method is the best one or which is suitable to a certain application. In this case, we set experiments in small-world and scale-free generated networks to certify the feasibility and characteristics of four approximating methods. We also use eleven real networks to mention different optimal conditions for these methods. We find the DIG Rank method performs better than other local estimation methods in almost every given sub graph. Besides, Mean field approach method tends to perform well in networks that have low average shortest path length, small amount of nodes with the same low in degree, or weak community structure. Finally, we apply the most versatile method DIG Rank to Sina micro-blog website to precisely classify users in a group as elites, grassroots or mummy users.
Coarticulatory organization for lip rounding in Turkish and English (1990)

A number of studies, involving English, Swedish, French, and Spanish, have shown that, for sequences of rounded vowels separated by nonlabial consonants, both EMG activity and lip protrusion diminish during the intervocalic consonant interval, producing a "trough" pattern. A two-part study was conducted to (a) compare patterns of protrusion movement (upper and lower lip) and EMG activity (orbicularis oris) for speakers of English and Turkish, a language where phonological rules constrain vowels within a word to agree in rounding and (b) determine which of two current models of coarticulation, the "look-ahead" and "coproduction" models, best explained the data. Results showed Turkish speakers producing "plateau" patterns of movement rather than troughs, and unimodal rather than bimodal patterns of EMG activity. In the second part of the study, one prediction of the coproduction model, that articulatory gestures have stable profiles across contexts, was tested by adding and subtracting movement data signals to synthesize naturally occurring patterns. Results suggest English and Turkish may have different modes of coarticulatory organization.
Croissance, propriétés structurales et optiques du silicium polymorphe (2001)

Le travail presente dans ce memoire de these est destine a la comprehension d'un nouveau materiau initialement mis en œuvre au LPICM: le silicium polymorphe (pm-Si). Le developpement de ce materiau est lie aux etudes de la formation de poudres dans les plasmas de silane. Les poudres sont des particules qui peuvent atteindre quelques microns de taille, mais les precurseurs sont en general des entites de taille nanometrique (nano-particules), qui peuvent etre cristallines ou amorphes. Le silicium polymorphe est deposee dans des conditions proches a la formation de poudres, ce qui devrait entrainer l'incorporation dans la couche de ces precurseurs nano-metriques. Depuis 1998 toute une serie d'experiences montrent que le pm-Si:H a une excellente qualite electrique par rapport au silicium amorphe hydrogene standard. C'est ceci qui a suscite l'interet aux etudes sur la structure et les conditions d'elaboration. Ce travail a ete abordee des trois points de vue differents: le plasma, la croissance et la structure. Plusieurs techniques ont du etre developpes a cause des particularites associees a cette etude. D'un cote, la Cavite Laser Resonante a permis de mesurer des concentrations de nano-particules dans laphase gaz de l'ordre de 10 puissance 8 -10 puissance 9 cm-3 dans des conditions de pm-Si:H. Des etudes in situ par Ellipsometrie Spectroscopique (SE) ont montre que la croissance du pm-Si:H se fait de maniere homogene. En meme temps, il a ete necessaire de developper le modele du Tetraedre pour comprendre la relation entre la fonction dielectrique du materiau obtenue par SE et sa structure. Enfin, des mesures en Microscopie Electronique a Transmission et Haute Resolution indiquent la presence de nano-cristallites dans une matrice amorphe. Des analyses sur la matrice amorphe indiquent une amelioration de l'ordre du pm-Si:H, correle avec l'amelioration des proprietes electroniques.
Increased cerebrospinal fluid concentration of nitrite in Parkinsonʼs disease (1995)

The concentration of nitrite, a metabolite of nitric oxide (NO), was increased in the cerebrospinal fluid (CSF) of untreated patients with Parkinson's disease and in patients treated with L-DOPA in comparison with a group of patients without dopaminergic dysfunction. There was no difference in the concentration of L-arginine (ARG), a precursor of NO, between the groups. There was a highly significant, linear relationship between the concentration of nitrite and ARG in the CSF suggesting that the production of NO is dependent on the availability of ARG. The results support the possibility that production of NO is increased in the brain in Parkinson's disease.