gebhart/patrepeval huggingface dataset:
Surfaces of Solids. XIII. A Vapor Adsorption Method for the Determination of the Area of a Solid without the Assumption of a Molecular Area, and the Areas Occupied by Nitrogen and Other Molecules on the Surface of a Solid (1944)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSurfaces of Solids. XIII. A Vapor Adsorption Method for the Determination of the Area of a Solid without the Assumption of a Molecular Area, and the Areas Occupied by Nitrogen and Other Molecules on the Surface of a SolidWilliam D. Harkins and George JuraCite this: J. Am. Chem. Soc. 1944, 66, 8, 1366–1373Publication Date (Print):August 1, 1944Publication History Published online1 May 2002Published inissue 1 August 1944https://pubs.acs.org/doi/10.1021/ja01236a048https://doi.org/10.1021/ja01236a048research-articleACS PublicationsRequest reuse permissionsArticle Views1286Altmetric-Citations435LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Case–control and prospective studies of dietary α-linolenic acid intake and prostate cancer risk: a meta-analysis (2013)

This analysis failed to confirm an association between dietary ALA intake and prostate cancer risk. Larger and longer observational and interventional studies are needed to define the role of ALA and prostate cancer.
Size-Controlled Synthesis of Polymer Nanoparticles with Tandem Acoustic Emulsification Followed by Soap-Free Emulsion Polymerization (2013)

We have developed a novel synthesis method for size-controlled polymer nanoparticles using soap-free emulsion polymerization. This new synthetic method involves sequential ultrasonic irradiation (20 kHz → 500 kHz → 1.6 MHz → 2.4 MHz) for acoustic emulsification of a water-insoluble monomer such as methylmethacrylate (MMA) in an aqueous medium, followed by emulsion polymerization in the obtained solution without using any surfactants. The sequential ultrasonication (tandem acoustic emulsification) could provide a clear and stable emulsified solution containing monomer droplets with relatively narrow size distribution in the nanometer range. The subsequent polymerization in this solution yielded size-controlled polymer nanoparticles. Furthermore, colloidal crystal films could be easily prepared from the as-polymerized nanoparticle solution using the fluidic-cell method.
A KRT71 Loss-of-Function Variant Results in Inner Root Sheath Dysplasia and Recessive Congenital Hypotrichosis of Hereford Cattle (2021)

Genodermatoses, such as heritable skin disorders, mostly represent Mendelian conditions. Congenital hypotrichosis (HY) characterize a condition of being born with less hair than normal. The purpose of this study was to characterize the clinicopathological phenotype of a breed-specific non-syndromic form of HY in Hereford cattle and to identify the causative genetic variant for this recessive disorder. Affected calves showed a very short, fine, wooly, kinky and curly coat over all parts of the body, with a major expression in the ears, the inner part of the limbs, and in the thoracic-abdominal region. Histopathology showed a severely altered morphology of the inner root sheath (IRS) of the hair follicle with abnormal Huxley and Henle's layers and severely dysplastic hair shafts. A genome-wide association study revealed an association signal on chromosome 5. Homozygosity mapping in a subset of cases refined the HY locus to a 690 kb critical interval encompassing a cluster of type II keratin encoding genes. Protein-coding exons of six positional candidate genes with known hair or hair follicle function were re-sequenced. This revealed a protein-changing variant in the <i>KRT71</i> gene that encodes a type II keratin specifically expressed in the IRS of the hair follicle (c.281delTGTGCCCA; p.Met94AsnfsX14). Besides obvious phenocopies, a perfect concordance between the presence of this most likely pathogenic loss-of-function variant located in the head domain of KRT71 and the HY phenotype was found. This recessive <i>KRT71</i>-related form of hypotrichosis provides a novel large animal model for similar human conditions. The results have been incorporated in the Online Mendelian Inheritance in Animals (OMIA) database (OMIA 002114-9913).
Digital passband processing of wideband-modulated optical signals for enhanced underwater imaging (2016)

Radar modulation, demodulation, and signal processing techniques have been merged with laser imaging to enhance visibility in murky underwater environments. The modulation provides a way to reject multiple scattered light that would otherwise reduce image contrast and resolution. Recent work has focused on the use of wideband modulation schemes and digital passband processing to resolve range details of an underwater scene. Use of the CLEAN algorithm has also been investigated to extract object features that are obscured by scattered light. Results from controlled laboratory experiments show an improvement in the range resolution and accuracy of underwater imagery relative to data collected with a conventional short pulse system.
The Influence of Cooling Rate between Ms and Mf on the Mechanical Properties of Low Alloy 42SiCr Steel Treated by the Q-P Process (2022)

A series of experiments was conducted by quenching and partitioning (Q-P) heat-treated alloys to investigate the effect of cooling intensity on the mechanical properties of low alloy steel 42SiCr. By applying a conventional heat treatment, reasonable high strength can be achieved; however, the alloys become more brittle. To obtain an optimal balance, advanced heat treatment methods like the Q-P process can be used. It consists of quenching to temperatures between martensite start and martensite finish temperatures and holding, which leads to the stabilization of untransformed austenite by carbon partitioning. The martensitic microstructure is then formed with a small volume fraction of retained austenite embedded on a microscopic scale. The material’s deformability can be significantly improved by using such heat treatment processes. Moreover, to improve advanced high strength properties (AHSS), an additional Q-P process can be applied, which leads to erasing the influence of cold forming as well as enhancement of the mechanical properties. Several combinations of the Q-P process with/without partitioning were performed with various cooling rates for both heat treatment methods. Ultimate Tensile Strength (UTS), Ductility and Hardness (HV10), as well as the microstructure of the alloys, are compared to evaluate the cooling intensity effects. The cooling rate is found not to be a significant factor influencing mechanical properties, which is a crucial point for practical material heat treatment.
[Effect of ligustrazine and L-arginine on function of mitochondria in myocardium after ischemia/reperfusion injury of myocardium in rabbits]. (2007)

LGT and IL-Arg can improve function of mitochondria in myocardium after ischemia/reperfusion injury of myocardium in rabbits by decreasing oxygen free radical level and Ca" overload in the mitochondria.
Experimental Study on Vehicle Dynamics Management by Active Brake Control Based on Tire Force Usage(Mechanical Systems) (2009)

It has been shown in our previous report that DYC is not compatible with the tire force usage equalization and it is important to consider total tire force F_x and F_y as feedback signals for DYC being compatible with the tire force usage equalization. Also, the control logic devised then has been found very effective in the electric vehicle run test. However, the vehicle dynamics control of a general car is controlled by the hydraulic brake system. In this report, our control logic is applied the hydraulic brake system of the electric vehicle, and an attempt has been made to clarify whether our control logic is effective or not for real vehicle by conducting real electric vehicle braking turn tests. According to the electric vehicle braking turn tests, the tire force usage rate has been not saturated by our control logic, and our control logic has improved the driving stability more than ABS of special condition and other DYC. It has been found that our control logic is very effective for braking turn of the independent wheel-in motor electric vehicle. Also, handling has become neutral steering by using our control logic at braking turn.
The RON Receptor Tyrosine Kinase Promotes Metastasis by Triggering MBD4-Dependent DNA Methylation Reprogramming (2014)

Metastasis is the major cause of death in cancer patients, yet the genetic and epigenetic programs that drive metastasis are poorly understood. Here, we report an epigenetic reprogramming pathway that is required for breast cancer metastasis. Concerted differential DNA methylation is initiated by the activation of the RON receptor tyrosine kinase by its ligand, macrophage stimulating protein (MSP). Through PI3K signaling, RON/MSP promotes expression of the G:T mismatch-specific thymine glycosylase MBD4. RON/MSP and MBD4-dependent aberrant DNA methylation results in the misregulation of a specific set of genes. Knockdown of MBD4 reverses methylation at these specific loci and blocks metastasis. We also show that the MBD4 glycosylase catalytic residue is required for RON/MSP-driven metastasis. Analysis of human breast cancers revealed that this epigenetic program is significantly associated with poor clinical outcome. Furthermore, inhibition of Ron kinase activity with a pharmacological agent blocks metastasis of patient-derived breast tumor grafts in vivo.
Dynamisches Verhalten von Silizium-Elektroden in Fluor-haltigen Elektrolyten (2004)

Einige Effekte von Silizium sind bis heute ungeklärt. Dazu zählt Oxidation von hoch-dotiertem n-Si in Fluor-haltigen Säuren im Dunkeln. Diese Oxidation wurde erstmals systematisch untersucht und zur Grundlage eines Modells für Elektroneninjektion gemacht. Die angenommenen Oberflächenkomplexen erklären den Einsatz der Kennlinien. Weitere Untersuchungen zur Identifizierung des Komplexes sowie seiner energetischen Position bieten sich an. Mit zyklischen Voltammogrammen wurde gezeigt, dass die Vorschubgeschwindigkeit des Potentials entscheidend für die Gestalt der Kennlinien ist. Schon 20mV/s ist für das untersuchte System zu schnell, um einen Gleichgewichtszustand zu erreichen. Dies wird durch die Ausbildung von Hysteresen klar erkennbar. Der initielle Strompuls zeigt eine vielfache Stromdichte gegenüber den bekannten Werten der nachfolgenden Oszillationspulse. Die Wasserstoff-terminierte Grenzfläche wird innerhalb weniger Zehntelsekunden oxidiert und passiviert. Alle nachfolgenden Strompulse können als weniger gut synchronisierte Oxidationen verstanden werden.
Characterization of an intestinal mucin from the peritrophic matrix of the diamondback moth, Plutella xylostella (2003)

The peritrophic matrix (PM) of Plutella xylostella larvae was found to contain twelve integral and eighteen loosely associated proteins. An antiserum against Mamestra configurata integral PM proteins cross-reacted with several P. xylostella PM proteins and was used to isolate a partial cDNA encoding an insect intestinal mucin (PxIIM). PxIIM was expressed primarily in the larval midgut. The deduced protein sequence of the partial cDNA contained three potentially glycosylated, mucin-like domains and six cysteine-rich chitin-binding domains (CBDs). An additional chitin-binding domain was proposed to reside at the amino terminus of the protein based on comparison with other IIM. The organization of mucin domains and CBDs exhibited features, including an internal triplet of regularly spaced CBDs and a carboxyl terminal CBD with two additional conserved cysteine residues, that were found to be common to other lepidopteran IIMs.
Conflict of Interest (1986)

Journal of Cataract & Refractive Surgery 12(1):p 64, January 1986. | DOI: 10.1016/S0886-3350(86)80063-3
Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound (2021)

Cerebral vasospasm that occurs in the weeks after subarachnoid hemorrhage, a type of hemorrhagic stroke, contributes to delayed cerebral ischemia. A problem encountered in experimental studies using murine models of SAH is that methods for in vivo monitoring of cerebral vasospasm in mice are lacking. Here, we demonstrate the application of high frequency ultrasound to perform transcranial Duplex sonography examinations on mice. Using the method, the internal carotid arteries (ICA) could be identified. The blood flow velocities in the intracranial ICAs were accelerated significantly after induction of SAH, while blood flow velocities in the extracranial ICAs remained low, indicating cerebral vasospasm. In conclusion, the method demonstrated here allows functional, noninvasive in vivo monitoring of cerebral vasospasm in a murine SAH model.
The Effects of Peripheral Simultaneous Competing Defocus Signals on Emmetropization in Infant Rhesus Monkeys (2016)

Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO), Seattle, WA, US, May 01-05, 2016
10-Gb/s BPSK link using Silicon Microring Resonators for Modulation and Demodulation (2014)

We demonstrate the first binary-phase-shift-keying (BPSK) link based on silicon microring resonators, with an operational bit-rate at 10 Gb/s. Bit-error-rate measurements and eye diagrams are used to compare the link’s performance with conventional BPSK modulation and demodulation techniques.
Reversing Light With Negative Refraction (2004)

Materials engineered to have negative permittivity and permeability demonstrate exotic behavior, from a negative refractive index to subwavelength focusing.
Evaluating the markov assumption for web usage mining (2003)

Web usage mining concerns the discovery of common browsing patterns, i.e., pages requested in sequence, from web logs. To cope with the enormous amounts of data, several aggregated structures based on statistical models of web surfing have appeared, e.g., the Hypertext Probabilistic Gramma(HPG) model [2]. These techniques typically rely on the Markov assumption with history depth n, i.e., it is assumed that the next requested page is only dependent on the last n pages visited. This is not always valid, i.e. false browsing patterns may be discovered. However, to our knowledge there has been no systematic study of the validity of the Markov assumption wrt. web usage mining and the resulting quality of the mined browsing patterns.In this paper we systematically investigate the quality of browsing patterns mined from structures based on the Markov assumption. Formal measures of quality, based on the closeness of the mined patterns to the true traversal patterns, are defined and an extensive experimental evaluation is performed, based on two substantial real-world data sets. The results indicate that a large number of rules must be considered to achieve high quality, that long rules are generally more distorted than shorter rules and that the model yield knowledge of a higher quality when applied to more random usage patterns. Thus we conclude that Markov-based structures for web usage mining are best suited for tasks demanding less accuracy such as pre-fetching, personalization, and targeted ads.
The Efficacy of Clarithromycin and the Bicyclolide EDP‐420 againstMycobacterium aviumin a Mouse Model of Pulmonary Infection (2008)

Lung disease caused by Mycobacterium avium complex (MAC) is increasing in prevalence. MAC disease occurs in patients with chronic preexisting obstructive pulmonary diseases but is also diagnosed in individuals with no history of lung pathology or identifiable immune defect. Histologically, the disease is characterized by either the development of nodular granulomatous lesions in the peribronchial region or cavitary peripheral disease in smokers. Response to long-term treatment is poor. Limited comparative-efficacy data on treatment exist. A model that resembles nodular MAC disease was established in C57 (bg+/bg+) mice infected intranasally. Therapy with clarithromycin, a compound commonly used to treat MAC disease, was evaluated in parallel with treatment using a new bicyclolide, EDP-420, that achieves high levels of intrapulmonary concentrations. Although clarithromycin administered daily resulted in a reduction in the bacterial load in the lung, EDP-420 administered either daily or twice a week was significantly more effective. These results suggest that this animal model can be used to evaluate novel regimens against MAC disease and that compounds with high concentration in the lung might have a significant impact on the outcome of MAC lung disease.
ChemInform Abstract: THE THERMAL POLYMERIZATION OF AMINO ACIDS, THE ROLE AND FATE OF THE REACTANTS (1975)

Abstract Mischungen von Asparaginsäure, Glutarninsäure, Glycin, Alanin, Valin, Leucin, Isoleucin und Prolin wurden auf 180 ‐ 190°C erhitzt und die erhaltenen Polymeren: gemische durch Dialyse, Gelfiltration, Chromatographie und Elektrophorese aufgetrennt.
A novel finite-element formulation for the analysis of the energy levels of a quantum cavity in a magnetic field (1998)

A novel finite-element formulation for the analysis of the energy levels of a two-dimensional quantum cavity in a magnetic field is proposed. Our formulation is based on both a variational and Galerkin methods which, when combined with a finite-element method, lead to eigenvalue problems characterized by either real or Hermitian matrices contrary to algorithms proposed in the past. These eigenvalue problems can then be solved quite efficiently on a computer using standard library packages. Also, it is confirmed that the results obtained here are independent of the choice of gauge.
A Timing-Driven Synthesis Technique for Arithmetic Product-of-Sum Expressions (2008)

The arithmetic product-of-sum (POS) is a frequently used datapath operation in modern integrated circuit designs, especially in digital signal processing (DSP) and graphics applications. Since POS blocks typically incur a significant amount of delay, these blocks often become critical in determining the performance of the entire chip. Hence, to improve the efficiency of this operation, it is desirable to use an architecture with good performance characteristics. This paper presents an architectural optimization approach to synthesize a faster POS block, which can be very useful in reducing the delay of the design without significantly impacting its area. Our architecture for the product-of-sum (POS) block is primarily based on the analysis of the corresponding sum-of-products (SOP) expression or a hybrid combination of the POS and the SOP expressions. In our technique, we extensively use arrival-times of the input signals of the product-of-sum block to determine the suitable architecture of the block. We have tested our approach using a variety of POS blocks implemented under varying timing constraints and technology libraries. Experimental results demonstrate that our proposed solution is 10.92% faster (and 3.54% larger) than the corresponding block generated by a commercially available best-in-class datapath synthesis tool. These improvements were verified on placed-and-routed designs as well.
An adaptive orthogonal transform coding algorithm for images utilizing classification technique (1989)

Abstract An adaptive orthogonal transform coding algorithm utilizing the classification technique is presented. Coding efficiency for natural images can be improved by adjusting coding parameters in accordance with the local property of images. “Classification” is used to categorize small areas of an image into classes based on their characteristics. High coding efficiency results from changing coding parameters adaptively according to the classification index. Classification methods using ac energy, binary pattern and vector quantization index are compared, and the advantage of the classification method with the vector quantization technique is shown. Also, an orthogonal transform coding algorithm with an adaptive variable length coding method is proposed, and its structure and characteristics are described. A coding parameter normalization method to avoid mismatches between input images and coding parameters is also described. Coding experiments show excellent performance of this algorithm, for example, the number of bits for obtaining 40‐dB SNR of monochrome “GIRL” is 0.65 bits/pel, which is 20 percent smaller than conventional methods.
Errata: Generation of time-reversed wave fronts by nonlinear refraction (1978)

Get PDF Email Share Share with Facebook Share on X Post on reddit Share with LinkedIn Add to Mendeley Add to BibSonomy Share with WeChat Get Citation Copy Citation Text R. W. Hellwarth, "Errata: Generation of time-reversed wave fronts by nonlinear refraction," J. Opt. Soc. Am. 68, 1155-1155 (1978) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
A new low-noise FET structure (1990)

A novel monolithic FET topology has demonstrated improved minimum noise figure when compared with a conventional pi-gate FET. The structure, referred to as the spider FET, has allowed noise figures to be achieved in monolithic LNA applications that are 0.3 dB lower than in the standard 0.5- mu m GaAs MESFET ion-implantation process. The improved spider FET performance is achieved by reducing the gate feed resistance and minimizing the parasitic gate-to-source capacitance in the region of the gate feed. The spider FET shows promise in 0.25- mu m MESFET and HEMT (high electron mobility transistor) applications, as well as in power FET applications.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
The aldolase-binding site of the human erythrocyte membrane is at the NH2 terminus of band 3. (1981)

Band 3 is the predominant membrane-spanning polypeptide and the mediator of anion transport in the human erythrocyte. In addition, it provides the sites of association for fructose 1,6-bisphosphate aldolase and other cytoplasmic proteins with the membrane. The aldolase-binding activity of water-soluble fragments of band 3 was measured by their inhibition of aldolase catalytic activity and by their displacement of aldolase from ghosts. At saturation, the binding of one band 3 or certain of its fragments per aldolase molecule partially inhibited the catalytic activity and band 3 binding of the unliganded subunits of the tetramer through an apparently cooperative mechanism. An NH2-terminal 23,000-dalton fragment generated by S-cyanylation of the cytoplasmic pole of band 3 was approximately 20% as avid in binding aldolase as was native band 3. Several fragments cleaved from the NH2-terminal portion of the 23,000-dalton peptide by trypsin, mild acid hydrolysis, and cyanogen bromide digestion all bound aldolase, while fragments from the rest of the polypeptide were essentially inactive. The first 31 residues of band 3 contained 16 Asp plus Glu, no basic residues, and a blocked alpha-amino terminus. The highly acidic composition of this region is consistent with the strongly electrostatic character of the interaction between band 3 and aldolase, presumably at the strongly basic catalytic center of the enzyme. We conclude that the NH2-terminal region of band 3 bears the membrane-binding site for aldolase.