gebhart/patrepeval huggingface dataset:
Bezout-based robust precoding for MIMO frequency selective channel using imperfect channel knowledge (2011)

In this paper, the problem of MIMO precoding is addressed for the case of single user, frequency selective wireless channel. Based on Bezout identity, two robust precoder designs are proposed that aim to inverse the effects of channel Intersymbol Interference (ISI) under two different scenarios of imperfect channel knowledge at the transmitter side. In the first one, specific statistical quantities of the channel are known at the transmitter while in the second one, a worst case scenario is adopted assuming that channel uncertainty falls within a given bounded set. Using standard optimization tools, both precoders are expressed in closed forms which are applicable for a wide range of channel conditions w.r.t. correlation in space and/or time, antenna numbers etc. Simulation results have shown that the proposed precoders perform comparably to the perfect channel knowledge case, offering at the same time some benefits in required transmitted power.
Effects of prolactin administered to a perfused area of the skin of Angora goats1,2 (2003)

It is suspected that prolactin may affect mohair growth; therefore, effects of infusing prolactin on mohair growth were investigated using a skin perfusion technique. Seven Angora wethers (average body weight, 30 +/- 3 kg) were implanted bilaterally with silicon catheters into the superficial branches of the deep circumflex iliac artery and vein. For the first 14 d of the experiment, animals were infused (2.4 mL/h) with prolactin (one side) or control (other side) into the deep circumflex iliac arteries. The infusion rate of prolactin was 2.21 mg/d and was calculated to triple prolactin blood concentration in the perfused region. The area of skin supplied by the deep circumflex iliac artery was approximately 240 cm2. Two weeks after the cessation of infusions, 100-cm2 areas within the perfused regions were shorn to determine mohair growth. Greasy and clean mohair production was decreased (P < 0.05) by prolactin compared with control (3.79 vs 4.62 and 3.02 vs 3.67 g/[100 cm2 x 28 d], respectively). Oxygen satura tion in blood hemoglobin from the deep circumflex iliac veins was greater (P < 0.02) on the side infused with prolactin than on the control side (75.1 vs 68.2%). Higher concentrations of methionine, lysine, valine, isoleucine, and leucine were observed in blood of the deep circumflex iliac vein on the side infused with prolactin vs that infused with control (P < 0.05). In conclusion, direct skin infusion with prolactin decreased mohair fiber synthesis by the skin and may have concomitantly lessened oxygen consumption. Thus, effects of increasing prolactin concentration approximately two-fold in the skin on mohair fiber growth may not be limited to simple competition for nutrients between skin and other tissues such as the mammary gland.
Recent Advances and Developments in Treatment Strategies Against Pancreatic Cancer (2009)

Recent years have seen improvements in strategies to treat pancreatic cancer. Pancreatic cancer is a leading cause of cancer-related death in the world, and is characterised by rapid disease progression, highly invasive tumour phenotype and resistance to chemotherapy. Patient prognosis is extremely grim, with a one-year survival rate of just 10% and only a 5% chance of surviving beyond five years. There has been little change in the treatment regimen, with 5-FU-based therapies being the usual route. Gemcitabine has also offered some relief over the past two decades, with modest improvements in median survival. This lack of choice has increased the call for new treatments, and indeed, novel drugs are now being investigated for their use in pancreatic cancer. These include those agents classically applied to other indications such as doxycycline and doxorubicin, as well as dietary components such as curcumin and genistein. Each of these drugs possesses different levels of activity both as single agents and in combinatorial approaches with gemcitabine. This review will discuss the difficulties in treating pancreatic cancer, and will summarise the progress and latest development in drugs used within this field of cancer.
Vertical MOS technology with sub-0.1 µm channellengths (1995)

A vertical MOSFET with a channel length of 85 nm has been fabricated by molecular beam epitaxy. Compared to previous work, the electrical behaviour has been greatly improved, allowing the use of standard simulation tools for analysing the I-V characteristics. From experimental and theoretical results, we conclude that for vertical MOSFETs, the useful minimum channel length is not limited by the technological constraints but by the physical limits of the electrical performance. The useful minimum channel length is estimated to be 80 nm.
Perioperative Antiplatelet Bridging With Cangrelor: A Cohort Study and Narrative Review (2022)

This study suggests that cangrelor bridging may be a reasonable alternative to holding oral P2Y12 inhibitors in patients requiring interruption of antiplatelet therapy for an urgent surgery/invasive procedure.
Expression of cellCAM-105 in the apical surface of rat uterine epithelium is controlled by ovarian steroid hormones (1990)

Affinity-purified antibodies to cellCAM-105, an adhesive cell surface glycoprotein, were used in immunohistochemical investigations of rat uteri at various functional stages: (i) the oestrous, pro-oestrous, metoestrous, and dioestrous stages of the oestrous cycle, (ii) Days 1-8 of normal pregnancy, (iii) delayed implantation, (iv) 18 h after oestrogen reactivation from delay of implantation, and (v) juvenile rats, and normal ovariectomized adults, respectively, before and after experimental injection of progesterone and/or oestrogen. CellCAM-105 was present in the apical zones of the luminal and glandular epithelium cells in a stage-specific and hormone-dependent manner. The results indicate that: (1) steroid hormones are essential for the expression of cellCAM-105 in the uterine epithelial cells; (2) progesterone induces cellCAM-105 expression in the glandular epithelium, and oestrogen induces cellCAM-105 expression in the luminal epithelium; (3) progesterone induces down-regulation of cellCAM-105 from the surface of the uterine luminal epithelium of juvenile rats; (4) cellCAM-105 is absent in the luminal epithelial cells but present in the glandular epithelial cells of the rat uterus at the time of blastocyst implantation.
Bloch Equations-Based Reconstruction of Myocardium T1 Maps from Modified Look-Locker Inversion Recovery Sequence (2015)

Modified Look-Locker Inversion recovery (MOLLI) sequence is increasingly performed for myocardial T1 mapping but is known to underestimate T1 values. The aim of the study was to quantitatively analyze several sources of errors when T1 maps are derived using standard post-processing of the sequence and to propose a reconstruction approach that takes into account inversion efficacy (η), T2 relaxation during balanced steady-state free-precession readouts and B1+ inhomogeneities. Contributions of the different sources of error were analyzed using Bloch equations simulations of MOLLI sequence. Bloch simulations were then combined with the acquisition of fast B1+ and T2 maps to derive more accurate T1 maps. This novel approach was evaluated on phantoms and on five healthy volunteers. Simulations show that T2 variations, B1+ heterogeneities and inversion efficiency represent major confounders for T1 mapping when MOLLI is processed with standard 3-parameters fitting. In vitro data indicate that T1 values are accurately derived with the simulation approach and in vivo data suggest that myocardium T1 are 15% underestimated when processed with the standard 3-parameters fitting. At the cost of additional acquisitions, this method might be suitable in clinical research protocols for precise tissue characterization as it decorrelates T1 and T2 effects on parametric maps provided by MOLLI sequence and avoids inaccuracies when B1+ is not homogenous throughout the myocardium.
Architecture and Experimental Validation of a Low-Latency Phasor Data Concentrator (2016)

This paper presents the design principles of a Phasor Data Concentrator (PDC) that implements both the absolute and relative time data pushing logics together with a third one that aims at minimizing the latency introduced by the PDC without increasing the data incompleteness, as suggested in the IEEE Guide C37.244-2013. The performance of the aforementioned logics are assessed and compared in terms of reliability, determinism, and reduction of the overall latency in two real Phasor Measurement Unit (PMU) installations adopting different telecom infrastructures. The first one is based on optical fiber links that transmit synchrophasor data measured by 15 PMUs installed in the sub-transmission network of the city of Lausanne, Switzerland. The second one adopts a 4G LTE wireless infrastructure to support the data streaming of 10 PMUs installed in a distribution network supplying the city of Huissen, The Netherlands. The experimental results show that the proposed logic is characterized by the lowest latency, whereas the absolute time logic better mitigates the synchrophasor data latency variations.
Microtubule severing by the katanin complex is activated by PPFR-1–dependent MEI-1 dephosphorylation (2013)

Katanin is an evolutionarily conserved microtubule (MT)-severing complex implicated in multiple aspects of MT dynamics. In Caenorhabditis elegans, the katanin homologue MEI-1 is required for meiosis, but must be inactivated before mitosis. Here we show that PPFR-1, a regulatory subunit of a trimeric protein phosphatase 4 complex, enhanced katanin MT-severing activity during C. elegans meiosis. Loss of ppfr-1, similarly to the inactivation of MT severing, caused a specific defect in meiosis II spindle disassembly. We show that a fraction of PPFR-1 was degraded after meiosis, contributing to katanin inactivation. PPFR-1 interacted with MEL-26, the substrate recognition subunit of the CUL-3 RING E3 ligase (CRL3(MEL-26)), which also targeted MEI-1 for post-meiotic degradation. Reversible protein phosphorylation of MEI-1 may ensure temporal activation of the katanin complex during meiosis, whereas CRL3(MEL-26)-mediated degradation of both MEI-1 and its activator PPFR-1 ensure efficient katanin inactivation in the transition to mitosis.
Light-driven molecular switch for reconfigurable spin filters (2019)

Artificial molecular switches and machines that enable the directional movements of molecular components by external stimuli have undergone rapid advances over the past several decades. Particularly, overcrowded alkene-based artificial molecular motors are highly attractive from the viewpoint of chirality switching during rotational steps. However, the integration of these molecular switches into solid-state devices is still challenging. Herein, we present an example of a solid-state spin-filtering device that can switch the spin polarization direction by light irradiation or thermal treatment. This device utilizes the chirality inversion of molecular motors as a light-driven reconfigurable spin filter owing to the chiral-induced spin selectivity effect. Through this device, we found that the flexibility at the molecular scale is essential for the electrodes in solid-state devices using molecular machines. The present results are beneficial to the development of solid-state functionalities emerging from nanosized motions of molecular switches.
Detailed analysis of HTT repeat elements in human blood using targeted amplification-free long-read sequencing (2018)

Amplification of DNA is required as a mandatory step during library preparation in most targeted sequencing protocols. This can be a critical limitation when targeting regions that are highly repetitive or with extreme guanine-cytosine (GC) content, including repeat expansions associated with human disease. Here, we used an amplification-free protocol for targeted enrichment utilizing the CRISPR/Cas9 system (No-Amp Targeted sequencing) in combination with single molecule, real-time (SMRT) sequencing for studying repeat elements in the huntingtin (HTT) gene, where an expanded CAG repeat is causative for Huntington disease. We also developed a robust data analysis pipeline for repeat element analysis that is independent of alignment of reads to a reference genome. The method was applied to 11 diagnostic blood samples, and for all 22 alleles the resulting CAG repeat count agreed with previous results based on fragment analysis. The amplification-free protocol also allowed for studying somatic variability of repeat elements in our samples, without the interference of PCR stutter. In summary, with No-Amp Targeted sequencing in combination with our analysis pipeline, we could accurately study repeat elements that are difficult to investigate using PCR-based methods.
Influence of global sperm DNA methylation on IVF results (2005)

DNA methylation level in human sperm could represent a new approach to study the ability of sperm to lead to pregnancy in an assisted reproduction procedure, especially when sperm samples with normal characteristics are used.
Urban Dew: Composition and Influence on Dry Deposition Rates (1986)

The composition of dew collected from a Teflon surface was compared to summer rainwater concentrations at a site in Warren, Michigan. This comparison showed that natural dew is similar to rainwater with the exception that dew has much higher concentrations of Ca+2 and Cl- and much lower acidity. Dry deposition rates of several species were measured to artificially-generated dew and a dry surface. It was found that deposition rates were 2 to 20 times greater to the artificial dew than to the dry surface indicating that the presence of dew enhances both the retention of dry deposited particles and the absorption of water soluble gases. Measurement of the atmospheric concentrations of the depositing species permitted the calculation of deposition velocities for particulate Cl-, NO-3, SO-24, Ca+2, Mg+2, Na+, and NH+4. Deposition velocities for gaseous HNO3, HCl, SO2 and NH3 were also determined after correction for particle deposition. These results indicate that acid dew is not a problem at this site. However, the ability of dew to increase the deposition rate of acids and acid precursors to some surfaces suggests that dew may be more acidic at sites with lower deposition rates of basic particles.
Synthesis of CeO[sub 2], ZrO[sub 2] Nanocrystals, and Core-Shell-Type Nanocomposites (2006)

The synthesis of core-shell nanocrystals (NCs), which are NCs overcoated by a thin layer, has been studied together with and NCs using a hot surfactant colloidal route. Colloidal solutions in oleylamine of the NCs with a diameter and NCs with a diameter were, respectively, synthesized by the thermolysis of and the reaction of and . The core-shell NCs have been successfully synthesized by the addition of NCs as seed crystals in the source solution and its reaction at . The core-shell nanostructure, which consists of a diameter core and thick shell, was supported by its X-ray diffraction, high-resolution transmission electron microscopy, and X-ray photoelectron spectroscopy results.
Self-Cleaning Particle Coating with Antireflection Properties (2005)

We report here a self-cleaning particle coating with antireflection (AR) properties. The coatings were prepared by (1) depositing SiO2 single-layered particle coatings on polyelectrolyte-modified glass substrates through electrostatic attraction, (2) subsequently depositing another layer of TiO2 nanoparticles through electrostatic attraction, and (3) removing the polymer by calcination at 500 °C. The AR effect of the coatings was studied with transmission spectra collected at normal incidence. The self-cleaning properties of the coatings were studied by the change of the water contact angle on octadodecyldimethylchlorosilane-modified coatings under 1.0 mW cm-2 ultraviolet light. Both the AR and self-cleaning properties of the coatings were dependent on the concentration of colloidal TiO2 solution used in the preparation. However, excellent surface wettability of the coatings for water was obtained, independent of the preparation conditions. The experimental findings are discussed in terms of the special structure of the particle coatings.
Smad4/DPC4-dependent Regulation of Biglycan Gene Expression by Transforming Growth Factor-β in Pancreatic Tumor Cells (2002)

Overexpression of the small leucine-rich proteoglycan biglycan (BGN) in fibrosis and desmoplasia results from enhanced activity of transforming growth factor-beta (TGF-beta). In pancreatic adenocarcinoma, the tumor cells themselves may contribute to BGN synthesis in vivo, since 8 of 18 different pancreatic carcinoma cell lines constitutively expressed BGN mRNA, as shown by reverse transcription-PCR analysis. In PANC-1 cells, TGF-beta1 dramatically stimulated BGN mRNA accumulation through a BGN transcription-independent, cycloheximide-sensitive mechanism and strongly increased the synthesis and release of the proteoglycan form of BGN. The ability of TGF-beta1 to induce BGN mRNA was critically dependent on Smad signaling, since 1) the up-regulation of BGN mRNA was preceded by a marked increase in Smad2 phosphorylation in TGF-beta1-treated PANC-1 cells, 2) TGF-beta1 was unable to induce BGN mRNA in pancreatic carcinoma cell lines that carry homozygous deletions of the Smad4/DPC4 gene, 3) inhibition of the Smad pathway in PANC-1 cells by transfection with a dominant negative Smad4/DPC4 mutant significantly reduced TGF-beta1-induced BGN mRNA expression, 4) stable reintroduction of wild type Smad4/DPC4 into Smad4-null CFPAC-1 cells restored the TGF-beta1 effect, and 5) overexpression of Smad2 and Smad3 in PANC-1 cells augmented TGF-beta1 induction of BGN mRNA, whereas forced expression of Smad7, an inhibitory Smad, effectively blocked it. These results clearly show that a functional Smad pathway is crucial for TGF-beta regulation of BGN mRNA expression. Since BGN has been shown to inhibit growth of pancreatic cancer cells, the Smad4/DPC4 mediation of the TGF-beta effect may represent a novel tumor suppressor function for Smad4/DPC4: antiproliferation via expression of autoinhibitory BGN.
Amplitude And Frequency Stabilization Of Solid-State Lasers (1989)

The investigations with the purpose to increase amplitude and frequency stability of a solid-state lasers, which may be applied in laser spectroscopy, metrology, communication, information processing, are reported. The spectral distribution of natural amplitude noise of cw solid-state lasers was considered. The effect of noise suppression at frequency of relaxation oscillation in laser with intracavity frequency doubling was analyzed as well as sub-Poissonian photon statistics. In the experiments with cw YAG:Nd lasers the amplitude noise close to natural limit was achieved over a wide range of fluctuation frequency. It was shown that the mentioned effect of noise suppression results the amplitude noise less then 0.001% over the range 10-200 kHz. The molecular cesium spectroscopic reference standard for long- term frequency stabilization in 1 &mu;m region is described. The sub-Doppler spectrum of Cs2 saturation absorption is represented over the YAG:Nd laser tuning range near the wavelength 1.06415 &mu;m. This spectrum produces the optical scale of reference frequencies, which looks favorable for various heterodyne applications. Frequency stabilization of YAG:Nd laser onto Cs2 absorption lines is reported. The Allan variance measurements provided the highest frequency stability of 6x10-11 relative units.
Slouching Towards Australian Public Libraries: The WTO General Agreement on Trade in Services (2005)

(2005). Slouching Towards Australian Public Libraries: The WTO General Agreement on Trade in Services. Australian Academic & Research Libraries: Vol. 36, Australian Indigenous Knowledge and Libraries, pp. 125-142.
Anticoagulation and induced hypertension after endovascular treatment for ruptured intracranial aneurysms (2001)

Induced hypertension (mean arterial blood pressure, 120 mm Hg) and heparinization do not appear to increase the risk of early rebleeding after GDC embolization. In a select group of patients, use of anticoagulation in the immediate perioperative period to prevent thromboembolic complications appears to be safe.
A New Javan Chilopod of the Genus Mecistocephalus (1922)

At Honolulu, Hawaii, a number of millipeds and centipeds were taken on Mar. 8, 1922, from soil of a shipment of plants from the Botanical Gardens of Buitenzorg, Java. Among these specimens, which were submitted to the writer for identification, were numerous specimens, mostly young, of the new species of Mecistocephalus described below. This form belongs to the lesser group of species in which the sternal impressions are not furcate anteriorly, and apparently has its nearest relatives in M. apator Chamberlin and M. monticolens Chamberlin, previously described from the same region. Two other chilopods were in the collection, Otosligmus fete Pocock being represented by one
A Hybrid FeMFET-CMOS Analog Synapse Circuit for Neural Network Training and Inference (2020)

An analog synapse circuit based on ferroelectric-metal field-effect transistors is proposed, that offers 6-bit weight precision. The circuit is comprised of volatile least significant bits (LSBs) used solely during training, and non-volatile most significant bits (MSBs) used for both training and inference. The design works at a 1.8V logic-compatible voltage, provides 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">10</sup> endurance cycles, and requires only 250ps update pulses. A variant of LeNet trained with the proposed synapse achieves 98.2% accuracy on MNIST, which is only 0.4% lower than an ideal implementation of the same network with the same bit precision. Furthermore, the proposed synapse offers improvements of up to 26% in area, 44.8% in leakage power, 16.7% in LSB update pulse duration, and two orders of magnitude in endurance cycles, when compared to state-of-the-art hybrid synaptic circuits. Our proposed synapse can be extended to an 8-bit design, enabling a VGG-like network to achieve 88.8% accuracy on CIFAR-10 (only 0.8% lower than an ideal implementation of the same network).