gebhart/patrepeval huggingface dataset:
Non-Faradaic Electrochemical Modification of the Catalytic Activity of Pt for H2Oxidation in Aqueous Alkaline Media (1996)

The heterogeneous catalytic oxidation of H2 on Pt was investigated on Pt black and Pt−graphite electrodes, also serving as heterogeneous catalysts, in aqueous alkaline solutions as a function of electrode potential and current. Hydrogen−oxygen mixtures were bubbled over the surface of the Pt electrode through a porous Teflon frit, and the rates of H2 and O2 consumption were measured via on-line mass spectrometry and gas chromatography. It was found that positive current application enhances the catalytic rate of H2 oxidation by up to 500% and that the increase in the catalytic rate is up to 100 times larger than the increase I/2F of the electrocatalytic rate corresponding to Faraday's law. The results show that the heterogeneously catalyzed H2 oxidation proceeds in parallel with the electrocatalytic anodic H2 oxidation and that its rate is markedly affected by the catalyst potential and work function. This electrochemically induced and controlled reversible promotion of the catalytic properties of Pt bears many similarities to the effect of electrochemical promotion when using solid electrolytes and can be rationalized by considering the effect of varying potential and work function on the coverages and binding strengths of dissociatively chemisorbed hydrogen and oxygen.
Synthesis, Fluorescence and Photoisomerization Studies of Azobenzene‐Functionalized Poly(alkyl aryl ether) Dendrimers (2004)

Abstract A series of azobenzene‐functionalized poly(alkyl aryl ether) dendrimers have been synthesized and their photochemical and photophysical properties in solution and as thin films have been investigated. Although the photochemical behavior of the azodendrimers in solution indicated that the azobenzene units behave independently, very similar to the constituent monomer azobenzene unit, the properties of thin solid films of the dendrimers were distinctly different. The azodendrimers, AzoG1 , AzoG2 , and AzoG3 were observed to form stable supercooled glasses, which showed long‐wavelength absorption and red emission characteristics of J‐aggregates of the azobenzene chromophores. Reversible photoinduced isomerization of the azodendrimers in the glassy state is described.
Spatial mapping of the DNA adducts in cancer (2023)

DNA adducts and strand breaks are induced by various exogenous and endogenous agents. Accumulation of DNA damage is implicated in many disease processes, including cancer, aging, and neurodegeneration. The continuous acquisition of DNA damage from exogenous and endogenous stressors coupled with defects in DNA repair pathways contribute to the accumulation of DNA damage within the genome and genomic instability. While mutational burden offers some insight into the level of DNA damage a cell may have experienced and subsequently repaired, it does not quantify DNA adducts and strand breaks. Mutational burden also infers the identity of the DNA damage. With advances in DNA adduct detection and quantification methods, there is an opportunity to identify DNA adducts driving mutagenesis and correlate with a known exposome. However, most DNA adduct detection methods require isolation or separation of the DNA and its adducts from the context of the nuclei. Mass spectrometry, comet assays, and other techniques precisely quantify lesion types but lose the nuclear context and even tissue context of the DNA damage. The growth in spatial analysis technologies offers a novel opportunity to leverage DNA damage detection with nuclear and tissue context. However, we lack a wealth of techniques capable of detecting DNA damage in situ. Here, we review the limited existing in situ DNA damage detection methods and examine their potential to offer spatial analysis of DNA adducts in tumors or other tissues. We also offer a perspective on the need for spatial analysis of DNA damage in situ and highlight Repair Assisted Damage Detection (RADD) as an in situ DNA adduct technique with the potential to integrate with spatial analysis and the challenges to be addressed.
Retraction for Fusco et al., “A mos Oncogene-Containing Retrovirus, Myeloproliferative Sarcoma Virus, Transforms Rat Thyroid Epithelial Cells and Irreversibly Blocks Their Differentiation Pattern” (2018)

[This retracts the article DOI: 10.1128/JVI.56.1.284-292.1985.].
Supplementary Tables 1 - 2 from HO-3867, a Safe STAT3 Inhibitor, Is Selectively Cytotoxic to Ovarian Cancer (2023)

&lt;p&gt;PDF file - 95K, Results of Tukey's post-hoc test and Molecular weights of the pure DAP compounds.&lt;/p&gt;
Macrophages Regulate Tissue Fibrosis in Lymphedema (2014)

Ghanta, Swapna MD; Cuzzone, Daniel A. MD; Albano, Nicholas J. BS; Savetsky, Ira L. MD; Gardenier, Jason C. MD; Torrisi, Jeremy S. BA; Joseph, Walter J. BS; Mehrara, Babak J. MD, FACS Author Information
Geranium essential oil: standardisation, ISO; adulteration and its detection using GC, enantiomeric columns, toxicity and bioactivity (2002)

The International Organisation for Standardization or ISO, defines Geranium oil as ‘The oil obtained by steam distillation of the fresh or slightly withered herbaceous parts of Pelargonium graveolens L’Heritier ex Aiton, Pelargonium roseum Willdenow and other undefined hybrids which have given rise to differing ecotypes in the various geographical areas’ (International standard 4731: 1972). The colour is various shades of amberyellow to greenish-yellow. The odour is given as characteristic of the origin, rose-like with a varying minty note.
Xurography : Simple, low-cost and versatile fabrication process for organic MEMS (2015)

National audience
Health care costs decline after successful epilepsy surgery (2007)

Costs remain stable over 2 years post-evaluation in patients with temporal lobe epilepsy whose seizures persist, but patients who become seizure free after surgery use substantially less health care than before surgery. Further cost reductions in seizure-free patients can be expected as antiepileptic drugs are successfully eliminated.
Tumor necrosis factor alpha-induced vascular leakage involves PECAM1 phosphorylation. (1996)

Herein we show that exposure of human umbilical vein endothelial cells to tumor necrosis factor alpha (TNFalpha) led to platelet endothelial cell adhesion molecule-1 (PECAM1) surface redistribution, disruption of cytoskeleton connections, and increased PECAM1 phosphorylation, accompanied by increased permeability to macromolecules. The in vitro use of inhibitors of tyrosine or serine-threonine kinases could prevent both PECAM1 surface redistribution and the increase in permeability induced by the cytokine. In vivo administration of lavendustin A, a natural tyrosine kinase inhibitor, protected endothelial cells from TNFalpha-dependent vascular leakage in mouse liver. We propose that the involvement of PECAM1 in TNFalpha-mediated effects on vascular permeability may depend on a dynamically regulated cytoskeletal association, related to the degree of PECAM1 phosphorylation.
Capacity Pre-Log of SIMO Correlated Block-Fading Channels (2011)

We establish an upper bound on the noncoherent capacity pre-log of temporally correlated block-fading single-input multiple-output (SIMO) channels. The upper bound matches the lower bound recently reported in Riegler et al. (2011), and, hence, yields a complete characterization of the SIMO noncoherent capacity pre-log, provided that the channel covariance matrix satisfies a mild technical condition. This result allows one to determine the optimal number of receive antennas to be used to maximize the capacity pre-log for a given block-length and a given rank of the channel covariance matrix.
[Occupational risk caused by ultrasound in medicine]. (1994)

Ultrasound (US) is extensively used in the medical field for its therapeutic and diagnostic applications. US units are commonly found in hospitals and clinics of all sizes, and a growing number of medical staff such as doctors and nurses are exposed to hand-transmitted ultrasound waves in their work-place. This review discusses the available information on the occupational risk of the operators using diagnostic and therapeutic ultrasound devices. The new occupational groups of medical workers who use ultrasound (diagnostic, surgical, sterilization, and physiotherapeutic) equipment are exposed to contact ultrasound waves. Contact ultrasound -- i.e., no airspace between the energy source and the biological tissue -- is much more hazardous than exposure to airborne ultrasound because air transmits less than one percent of this kind of energy. In spite of being a non-ionizing radiation with an excellent safety record, US is likely to induce some changes in the exposed organ. Recent Russian studies indicate that the hospital workers who have been long exposed to ultrasound at work may develop neurovascular dose-dependent disorders of the peripheral nervous system in the form of the angiodystonic syndrome of vegetative polyneuritis of the hands. In some Scandinavian studies, female physiotherapists (exposed to ultrasound and short waves) exhibit increased rate of spontaneous abortions and congenital malformations, but no definite conclusion can be drawn on the basis of these results alone. Trends in exposure for diagnostic ultrasound equipment over the last two decades show a continuous increase. While there is no reason for alarm, there is a growing need for avoiding unnecessary exposure to medical workers.
Optimized Gallium Arsenide Modulators for Advanced Modulation Formats (2013)

We review the guided-wave subcomponents required in the design of high-functionality modulators for advanced modulation formats using the GaAs/AlGaAs material system. In these complex devices, small loss contributions rapidly accumulate unless the substructures are well optimized, not only for low loss but also for process tolerance. Results for an advanced 40-Gb/s DQPSK modulator are presented.
Efficient management of security and privacy issues in mobile cloud environment (2013)

Mobile cloud computing is becoming more and more popular among mobile users and developers who can see a direct benefit to overcome the resource limitations in mobile devices - be it battery life, memory space or processing power. The widespread adoption of programmable smart mobile devices and connecting to public domain of internet as well as cloud service providers provide newer privacy as well as security challenges across enterprises. Data loss from stolen or decommissioned mobile devices, unsecured information exchange through rouge access points and access of vulnerable network fetch privacy as well as security threats of mobile cloud computing. Data breaches, account hijacking, insecure API exposure, denial of services, malicious insider attacks, loss of encryption key, virtual machine isolation bring forth some of the additional security and privacy threats. In this paper, we have attempted to enumerate several privacy plus security threats and put forth best practices and recommendations as preventive as well counter measures on incidence. We have evaluated the provisioning of services such as Security as a Service (SecaaS) in different scenarios and practices based on the requirement of individual applications.
Prospective motion correction of X-ray images for coronary interventions (2005)

A method for prospective motion correction of X-ray imaging of the heart is presented. A 3D + t coronary model is reconstructed from a biplane coronary angiogram obtained during free breathing. The deformation field is parameterized by cardiac and respiratory phase, which enables the estimation of the state of the arteries at any phase of the cardiac-respiratory cycle. The motion of the three-dimensional (3-D) coronary model is projected onto the image planes and used to compute a dewarping function for motion correcting the images. The use of a 3-D coronary model facilitates motion correction of images acquired with the X-ray system at arbitrary orientations. The performance of the algorithm was measured by tracking the motion of selected left coronary landmarks using a template matching cross-correlation. In three patients, we motion corrected the same images used to construct their 3D + t coronary model. In this best case scenario, the algorithm reduced the motion of the landmarks by 84%-85%, from mean RMS displacements of 12.8-14.6 pixels to 2.1-2.2 pixels. Prospective motion correction was tested in five patients by building the coronary model from one dataset, and correcting a second dataset. The patient's cardiac and respiratory phase are monitored and used to calculate the appropriate correction parameters. The results showed a 48%-63% reduction in the motion of the landmarks, from a mean RMS displacement of 11.5-13.6 pixels to 4.4-7.1 pixels.
Ca48+Bk249Fusion Reaction Leading to ElementZ=117: Long-Livedα-DecayingDb270and Discovery ofLr266 (2014)

The superheavy element with atomic number Z 117 was produced as an evaporation residue in the 48 Ca 249 Bk fusion reaction at the gas-filled recoil separator TASCA at GSI Darmstadt, Germany. The radioactive decay of evaporation residues and their -decay products was studied using a detection setup that allowed measuring decays of single atomic nuclei with half-lives between sub-s and a few days. Two decay chains comprising seven decays and a spontaneous fission each were identified and are assigned to the isotope 294 117 and its decay products. A hitherto unknown -decay branch in 270 Db (Z 105) was observed, which populated the new isotope 266 Lr (Z 103). The identification of the long-lived (T 1=2 1.0 1.9 -0.4 h) -emitter 270 Db marks an important step towards the observation of even more long-lived nuclei of superheavy elements located on an "island of stability."
Detection Theory for Union of Subspaces (2018)

The focus of this paper is on detection theory for union of subspaces (UoS). To this end, generalized likelihood ratio tests (GLRTs) are presented for detection of signals conforming to the UoS model and detection of the corresponding “active” subspace. One of the main contributions of this paper is bounds on the performances of these GLRTs in terms of geometry of subspaces under various assumptions on the observation noise. The insights obtained through geometrical interpretation of the GLRTs are also validated through extensive numerical experiments on both synthetic and real-world data.
Evaluation of Coating Performance on Silver Exposed to Hydrogen Sulfide (2013)

Twelve coatings applied to sterling silver coupons were subjected to high levels of hydrogen sulfide to test their effectiveness in preventing tarnish in indoor environments. Silver coupons were assessed over the course of the experiment using visual observation, image analysis of digital photographs, gloss measurement, and colorimetry. Acrysol WS-24, Agateen Air Dry Lacquer No. 27, HMG Heat and Waterproof Adhesive, and PVAc AYAT generally performed best. Mowiol 28-99 performed very well on some areas but was mediocre otherwise. Butvar B-98 and Acryloid B-48N were generally less effective in retarding tarnish. Acryloid B-72 and Butvar B-76 performed less well. Aquazol 500, Aquazol 500 topped with Renaissance Wax, and Renaissance Wax were least effective. Coating thickness proved to be a significant factor in coating performance.
Table S3 from Optimized EGFR Blockade Strategies in <i>EGFR</i> Addicted Gastroesophageal Adenocarcinomas (2023)

&lt;p&gt;Supplementary Table 3&lt;/p&gt;
Studying the Reliability of Ge nFinFETs by the Normalized Input-referred Voltage Noise (2020)

Due to the pre-existing defects in gate stack, especially in high - κ dielectric layer, the PBTI degradation for advanced devices become more prominent than devices with conventional Poly/SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> gate stack. The input referred voltage noise (Svg) has a close relationship with oxide traps in gate stack, and the result shows its value at inner high-κ dielectric layer can be regarded as an indicator of PBTI degradation. It is shown that as the fin width (Wfin) decreases from 100nm to 16nm, Svgfb decreases firstly and then increases. The total component for BTI degradation that comes from oxide vacancies in the high-κ layer and the interface density (Dit) induces the degradation of the PBTI reliability with the decrease of Wfin.
Research Article: Effective and Specific Inhibition of the CD40–CD154 Costimulatory Interaction by a Naphthalenesulphonic Acid Derivative (2010)

Costimulatory interactions are important regulators of T-cell activation and, hence, promising therapeutic targets in autoimmune diseases as well as in transplant recipients. Following our recent identification of the first small-molecule inhibitors of the CD40-CD154 costimulatory protein-protein interaction (J Mol Med 87, 2009, 1133), we continued our search within the chemical space of organic dyes, and we now report the identification of the naphthalenesulphonic acid derivative mordant brown 1 as a more active, more effective, and more specific inhibitor. Flow cytometry experiments confirmed its ability to concentration-dependently inhibit the CD154(CD40L)-induced cellular responses in human THP-1 cells at concentrations well below cytotoxic levels. Binding experiments showed that it not only inhibits the CD40-CD154 interaction with sub-micromolar activity, but it also has considerably more than 100-fold selectivity toward this interaction even when compared to other members of the tumor necrosis factor superfamily pairs such as TNF-R1-TNF-α, BAFF-R(CD268)-BAFF(CD257/BLys), OX40(CD134)-OX40L(CD252), RANK(CD265)-RANKL(CD254/TRANCE), or 4-1BB(CD137)-4-1BBL. There is now sufficient structure-activity relationship information to serve as the basis of a drug discovery initiative targeting this important costimulatory interaction.
A multicenter, phase II trial of GC1118, a novel anti‐EGFR antibody, for recurrent glioblastoma patients with EGFR amplification (2023)

This study did not meet the primary endpoint (PFS6); however, we found that immune signatures were significantly upregulated in the tumors with regression upon GC1118 therapy, which signifies the potential of immune-mediated antitumor efficacy of GC1118.
Apex Lake (2015)

The introduction of a Software-defined infrastructures brings additional challenges to the management of cloud infrastructure. With the impending convergence of telecommunications and cloud infrastructures, datacenters become an essential part of an overall integrated environment. The potential scale of such environments has significant implications as traditional orchestration approaches cannot scale appropriately. However, the combination of infrastructure topology, fine-grained operational data and advanced analytics, has the potential to deliver a scalable approach to facilitate orchestration and resource management. In this paper we introduce Apex Lake, a framework designed to address the question of "how to efficiently define and maintain a physical and logical resource and service landscape enriched by operational data, to support orchestration for optimized service delivery?" We also demonstrate with a use-case illustrating how functionalities provided by Apex Lake can be used dealing with performance anomalies.
Hidden Markov model-based predictive maintenance in semiconductor manufacturing: A genetic algorithm approach (2017)

The accuracy of data-mining based predictive maintenance often relies on extensive process and machine knowledge to enable appropriate feature selection and data preprocessing. Measurement data obtained may be asynchronous and result in inaccurate features, affecting the accuracy of maintenance prediction. To overcome this drawback, this paper introduces an approach to automatically select a feature subset through a genetic algorithm. The full feature set is created based on different sliding windows characterizing different time shifts on adopted statistical metrics of the measurement data. The fitness function of the genetic algorithm is then developed based on the preliminary fitting of a hidden Markov model (HMM) on the selected subset of features and assumed machines' condition in the training data. Ultimately the fittest subset of features is used to enable HMM-based predictive maintenance. The proposed approach is evaluated using data from semi-conductor wafer production equipment, recorded over a period of one year.
Rigid Films of an Anionic Porphyrin and a Dialkyl Chain Surfactant (2007)

The 2D complex formed at the air-water interface between the dialkyl chain cationic surfactant, dihexadecyldimethylammonium bromide, and the anionic porphyrin, tetrakis-(4-sulfonatophenyl) porphine, was studied using surface pressure-area isotherms as well as X-ray and neutron reflection measurements. The surface structure of these films was determined by the use of simultaneously constrained analysis of the neutron and X-ray reflectometry data and BAM images. Isotopic contrast variation methods were employed to enhance the information content of the neutron reflection data. The rigid complex forms at the interface due to the electrostatic interaction between the cationic headgroups of the surfactant and the anionic functional groups at the meso position of the porphyrin. The surface pressure-area isotherms show three distinct regions on compression: an initial condensed phase that ends with a pressure peak at 36 mN m-1, a second plateau region of high compressibility, and a final condensed phase. BAM images show that at the beginning of the plateau region in the isotherm there is complete surface coverage by a monolayer. The constrained simultaneous fitting of neutron and X-ray data measured just prior to and after the pressure peak shows a structurally similar 2D complex at the interface. Modeling of X-ray reflectometry data also reveals that in the final high-pressure phase the film has folded to form a trilayer. The conclusion is that the plateau region of the isotherm is due to the formation of trilayer surface coverage through localized buckling or folding, and that after this is complete there is some condensation before final film collapse.
Development of Copolyamide-66/6 Cross-Linked Foams by a One-Step Reactive Extrusion Process (2019)

The simultaneous chemical cross-linking and foaming of aliphatic copolyamide by one-step reactive extrusion using a bifunctional trialkoxysilaneimidazoline additive is studied. The aim was to reach efficient melt strength enhancing the cell growth without coalescence. From liquid NMR analyses, the cross-linked foam synthesis was evidenced resulting from both imidazoline ring opening (further reacting with the polyamide carboxylic acid end-groups) and alkoxysilane hydrolysis–condensation reactions (leading to cross-linking reaction and ethanol formation). From these chemical modifications, ethanol concomitantly released lead to the expansion of the cross-linked copolyamide. From the knowledge of this chemical mechanism, various extruder and formulation parameters have been modified and their impact scrutinized to optimize the foam morphology. With our optimized conditions, it was possible to synthesize rigid foam with mean pore size mainly below 90 μm and a density around 0.36 kg·m–3 while reaching reasonable compression properties (normalized modulus at 330 MPa). The maximum cell density obtained was 3 × 105 cells·cm–3.