gebhart/patrepeval huggingface dataset:
Ionization Constants and Ultraviolet Spectra of Fluoro and Trifluoromethyl trans-Cinnamic Acids. (1964)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIonization Constants and Ultraviolet Spectra of Fluoro and Trifluoromethyl trans-Cinnamic Acids.Robert. Filler, I. J. Solomon, and F. N. MillerCite this: J. Chem. Eng. Data 1964, 9, 3, 370Publication Date (Print):July 1, 1964Publication History Published online1 May 2002Published inissue 1 July 1964https://pubs.acs.org/doi/10.1021/je60022a016https://doi.org/10.1021/je60022a016research-articleACS PublicationsRequest reuse permissionsArticle Views59Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Urinary Excretion of Aquaporin-2 in Patients with Diabetes Insipidus (1995)

Aquaporin-2 is detectable in the urine, and changes in the urinary excretion of this protein can be used as an index of the action of vasopressin on the kidney.
Draft Genome Sequence of Enterococcus faecalis UMB1309, Isolated from Catheterized Urine (2020)

A strain of <i>Enterococcus faecalis</i> was isolated from catheterized urine. Here, we present the draft genome sequence of this isolate, <i>E. faecalis</i> UMB1309. Analysis of the genome revealed multiple genes coding for virulence factors, as well as genes associated with antibiotic resistance.
Treating Anterior Cruciate Ligament Tears in Skeletally Immature Patients (2011)

Level IV, systematic review of Level II, III, and IV studies.
Understanding FVIII/VWF complex – report from a symposium of XXIX WFH meeting 2010 (2011)

von Willebrand factor (VWF) has the capacity to form a complex with factor VIII (FVIII) which may modulate the immunogenicity of FVIII. It has been proposed that a significant fraction of recombinant FVIII (rFVIII) is unable to bind VWF. In an experimental model studied at the McMaster University in Canada, this VWF-unbound rFVIII fraction showed no coagulant function. Sulphation of FVIII tyrosine (Tyr) 1680 has been reported as essential for the interaction with VWF. In a study performed at the Grifols and CNS-CSIC in Spain, Tyr1680 sulphation was observed to be incomplete in rFVIII and complete in plasma-derived FVIII (pdFVIII). This could explain the incapability of some rFVIII molecules to bind VWF. Experience with immune tolerance induction (ITI) at the Bonn Haemophilia Centre indicates that only eradication of FVIII inhibitors allows safe haemostasis control and the option of prophylactic treatment. Various clinical trials were planned to evaluate the clinical role VWF-containing FVIII concentrates (FVIII/VWF). RES.I.ST (an acronym for REScue Immunotolerance STudy) is an international, prospective study aimed at assessing whether FVIII/VWF can induce ITI in high-risk haemophilia patients (RES.I.ST naïve) and whether patients who previously failed ITI with FVIII alone can be rescued with FVIII/VWF (RES.I.ST experienced). Enrolment started in November 2009. In the FAIReSt.Will (Fanhdi and Alphanate Italian Retrospective Study in Willebrand disease) study, 120 von Willebrand disease (VWD) patients treated with Fanhdi(®) or Alphanate(®) were retrospectively analysed. Efficacy was excellent and no side effects were reported. The ongoing PRO.Will study is a prospective, multicenter trial aimed at assessing the efficacy, safety and pharmacoeconomics of secondary long-term prophylaxis in patients with severe inherited VWD.
Green synthesis of propylene oxide directly from propane (2022)

The chemical industry faces the challenge of bringing emissions of climate-damaging CO2 to zero. However, the synthesis of important intermediates, such as olefins or epoxides, is still associated with the release of large amounts of greenhouse gases. This is due to both a high energy input for many process steps and insufficient selectivity of the underlying catalysed reactions. Surprisingly, we found that the oxidation of propane at elevated temperature over inert materials such as boron nitride and silicon dioxide leads to the formation of significant amounts of propylene oxide in a mixture with propylene, with unexpectedly small amounts of CO2 being formed. Fragile products are usually synthesised on highly specific surfaces, which is associated with strong interactions. We demonstrate that rapid reaction over unspecific interfaces entails im-portant consequences for the synthesis of products prone to overoxidation. Process simulations reveal that the combined synthesis of these two important chemical building blocks is technologically feasible. Our discovery leads the ways towards an environmentally friendly production of propylene oxide and propylene in one step. A complex catalyst development is not necessary.
Fatigue to Fracture: An Informative, Fast, and Reliable Approach for Assessing Medical Implant Durability (2009)

Abstract This paper compares the differences between the “test to success” and “test to fracture” paradigms for medical implant durability assessment. It recognizes that test to success can be one of the tests within test to fracture, in addition to a series of shorter cycle, higher force/deformation tests. In addition, by “testing to fracture,” one can validate the fatigue analysis capability, learn the consequences of in vitro fractures, and provide information that can either be used for product improvement or for clinicians to make life-saving decisions.
Rates of fish waste production and effluent discharge from a recirculating system (biofish) under commercial conditions (1995)

Application of the regulatory principle of ‘best available technology’ (BAT) to fish farm effluent control has, to some extent, been a driving force for the development of new culture and treatment technology. In Norway today, there are a number of farms for the production of Atlantic salmon, Salmo salar L., smolts and brown trout, Salmo trutta L., fingerlings that utilize microstrainers for the removal of particles from the effluent water. At least one commercial farm also utilizes a simplified recirculation system called BIOFISH as a demonstration of new and alternative technology for the production of brown trout restocking fish. In this paper, calculated effluent discharge and rates of waste production from the biofish demostration trials are compared to literature data and to measurements on un-treated as well as microstrained effluents from the production of Atlantic salmon smolts in a traditional flow-through tank system. Rates of fish waste production in the biofish trials were obtained from mass-balance calculations based on measured concentrations of water quality parameters at several points in the system. The results of these calculations show fish waste production rates that are low, but comparable to data found in the literature. Given the level of waste treatment that takes place in the biofish tanks, the specific effluent discharge levels from those tanks, in terms of grams per kilogram biomass and grams per kilogram feed, are considerably lower than those found for salmon smolt production in traditional flow-through tanks. There are also substantial differences in hydraulic self-cleaning properties of the two systems and a corresponding difference in the distribution of effluent discharge during normal tank operation and during tank/effluent pipeline flushing. The results presented here give valuable information related to: (1) waste output characterization; (2) the long-term efficiency of commercially available particle separation systems; and (3) the capabilities of the simplified biofish recirculation technology under field conditions.
Case report: The promising application of dynamic functional connectivity analysis on an individual with failed back surgery syndrome (2022)

Failed back surgery syndrome (FBSS), a chronic neuropathic pain condition, is a common indication for spinal cord stimulation (SCS). However, the mechanisms of SCS, especially its effects on supraspinal/brain functional connectivity, are still not fully understood. Resting state functional magnetic resonance imaging (rsfMRI) studies have shown characteristics in patients with chronic low back pain (cLBP). In this case study, we performed rsfMRI scanning (3.0 T) on an FBSS patient, who presented with chronic low back and leg pain following her previous lumbar microdiscectomy and had undergone permanent SCS. Appropriate MRI safety measures were undertaken to scan this subject. Seed-based functional connectivity (FC) was performed on the rsfMRI data acquired from the FBSS subject, and then compared to a group of 17 healthy controls. Seeds were identified by an atlas of resting state networks (RSNs), which is composed of 32 regions grouped into 8 networks. Sliding-window method and k-means clustering were used in dynamic FC analysis, which resulted in 4 brain states for each group. Our results demonstrated the safety and feasibility of 3T MRI scanning in a patient with implanted SCS system. Compared to the brain states of healthy controls, the FBSS subject presented very different FC patterns in less frequent brain states. The mean dwell time of brain states showed distinct distributions: the FBSS subject seemed to prefer a single state over the others. Although future studies with large sample sizes are needed to make statistical conclusions, our findings demonstrated the promising application of dynamic FC to provide more granularity with FC changes associated with different brain states in chronic pain.
Ostriches Sleep like Platypuses (2011)

Mammals and birds engage in two distinct states of sleep, slow wave sleep (SWS) and rapid eye movement (REM) sleep. SWS is characterized by slow, high amplitude brain waves, while REM sleep is characterized by fast, low amplitude waves, known as activation, occurring with rapid eye movements and reduced muscle tone. However, monotremes (platypuses and echidnas), the most basal (or 'ancient') group of living mammals, show only a single sleep state that combines elements of SWS and REM sleep, suggesting that these states became temporally segregated in the common ancestor to marsupial and eutherian mammals. Whether sleep in basal birds resembles that of monotremes or other mammals and birds is unknown. Here, we provide the first description of brain activity during sleep in ostriches (Struthio camelus), a member of the most basal group of living birds. We found that the brain activity of sleeping ostriches is unique. Episodes of REM sleep were delineated by rapid eye movements, reduced muscle tone, and head movements, similar to those observed in other birds and mammals engaged in REM sleep; however, during REM sleep in ostriches, forebrain activity would flip between REM sleep-like activation and SWS-like slow waves, the latter reminiscent of sleep in the platypus. Moreover, the amount of REM sleep in ostriches is greater than in any other bird, just as in platypuses, which have more REM sleep than other mammals. These findings reveal a recurring sequence of steps in the evolution of sleep in which SWS and REM sleep arose from a single heterogeneous state that became temporally segregated into two distinct states. This common trajectory suggests that forebrain activation during REM sleep is an evolutionarily new feature, presumably involved in performing new sleep functions not found in more basal animals.
Self organized nanostructures of vapor phase grown CuGaS<inf>2</inf> thin films (2009)

Thin films of nanocrystalline CuGaS <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> chalcopyrites have been prepared by chemical vapor transport (CVT) using elements of Cu, Ga, and S with iodine as the transporting agent. Crystalline layers of CuGaS <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> have been grown using various iodine concentrations but with constant source materials, growth zones temperatures and growth durations. The films were grown onto sapphire (Al <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> O <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</inf> ) substrates. The deposits obtained were nanostructures of CuGaS2 thin films and they were characterized by field emission scanning electron microscopy (FESEM), energy dispersive X-ray analysis (EDAX), transmission electron microscopy (TEM), selected area electron diffraction (SAED), glancing angle X-ray diffraction (GAXRD), X-ray rocking curve, optical, Raman spectroscopy and by photoluminescence (PL) measurements. As-grown different iodine concentration CuGaS <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> nanocrystalline thin films have shown p-type conductivity.
Surface-enhanced Raman scattering molecular nanoprobes (2005)

Nanoparticles are increasingly finding a wide application in the biological studies due to their unique physical and chemical properties. Colloidal nanoparticles are efficient substrate that exhibit surface-enhanced Raman scattering (SERS) phenomenon by enhancing the scattering cross-sections of conjugated Raman active molecules thus enabling highly sensitive biological probes. However, biological and medical applications would require nanoparticles to be conjugated to biomolecules. A universal approach for conjugation of mercarptoacetic acid-capped silver nanoparticles to biomolecules is described. The surface functionalized silver colloids were labeled with a Raman active dye and used for cellular imaging. We also described the use of silver nanoparticle to develop a new class of SERS nanoprobes for molecular recognition and detection of specific nucleic acid sequences.
Sediment Transport in a Precambrian Ice Age: The Huronian Gowganda Formation (1966)

The Gowganda Formation of Ontario consists of conglomerates, quartzites, and argillites deposited in a glacial environment. The distribution of varved argillites and silty limestones suggests continental and marine facies, respectively. Pebble and ripple-drift orientations, distribution of limestones, striated pavements, distribution of the underlying Bruce Group, and Huronian quartzite paleocurrents support the conclusion that sediment transport was from north to south.
Articulatory speech recognition using hierarchical, interpolating hidden Markov models (1998)

Articulatory speech recognizers infer the configuration and movement of a speaker’s vocal apparatus as an intermediate representation between acoustics and phonetics. Articulatory modeling makes coarticulation processes explicit, as opposed to the conventional triphone technique of elaborating all coarticulation combinations. In the present study, hierarchical, interpolating hidden Markov models (HMMs) transform acoustics into articulation and articulation into phonetics. Articulatory and acoustic data with transcriptions are used for both training and testing. The articulatory data, collected by the University of Wisconsin, consist of synchronized recordings during speech of x-ray microbeam positions, throat vibration, and acoustics. State variables of the Markov model represent articulator configurations. These variables change continuously between targets to represent coarticulation. In this model, their state changes are driven by a top-level state variable which changes from phone to phone. The model emits both articulator positions and acoustic analysis coefficients, when viewed as a generator (in recognition, these emissions are the inputs). Variational techniques make the training problem tractable. The latest phonetic-recognition results of the model will be contrasted with baseline HMM systems trained on acoustic and articulatory data. [Work supported in part by NIMH, the NSF/DARPA STC for Computer Graphics and Scientific Visualization, and Hewlett–Packard.]
Time domain nonlinear structures and substructures for ultrafast photonics (2014)

International audience
Recycling and Burial of Biogenic Silica in an Open Margin Oxygen Minimum Zone (2020)

Abstract An extensive data set of biogenic silica (BSi) fluxes is presented for the Peruvian oxygen minimum zone (OMZ) at 11°S and 12°S. Each transect extends from the shelf to the upper slope (∼1,000 m) and dissects the permanently anoxic waters between ∼200 and 500 m water depth. BSi burial (2,100 mmol m −2 yr −1 ) and recycling fluxes (3,300 mmol m −2 yr −1 ) were highest on the shelf with mean preservation efficiencies (34% ± 15%) that exceed the global mean of 10%–20%. BSi preservation was highest on the inner shelf (up to 56%), decreasing to 7% and 12% under anoxic waters and below the OMZ, respectively. The data suggest that the main control on BSi preservation is the rate at which reactive BSi is transported away from undersaturated surface sediments by burial and bioturbation to the underlying saturated sediment layers where BSi dissolution is thermodynamically and/or kinetically inhibited. BSi burial across the entire Peruvian margin between 3°S to 15°S and down to 1,000 m water depth is estimated to be 0.1–0.2 Tmol yr −1 ; equivalent to 2%–7% of total burial on continental margins. Existing global data permit a simple relationship between BSi rain rate to the seafloor and the accumulation of unaltered BSi, giving the possibility to reconstruct rain rates and primary production from the sediment archive in addition to benthic Si turnover in global models.
Rapid Method for the Ring Expansion of 1,3-Dithiolanes and 1,3-Dithianes with tert-Butyl Hypochlorite (2005)

A new method for the ring expansion of 1,3-dithiolanes and 1,3-dithianes to dihydro-1,4-dithiins and dihydro-1,4-dithiepines, respectively, using tert-butyl hypochlorite at room temperature is described. The salient features of the protocol include mild reaction conditions, very short reaction time, and high yield.
THE SYNTHESIS OF CONDENSED RING COMPOUNDS. XII.1 THE PREPARATION OF A 5,6,8-TRIKETO-9-METHYL-2-OCTALIN2 (1943)

ADVERTISEMENT RETURN TO ISSUEArticleNEXTTHE SYNTHESIS OF CONDENSED RING COMPOUNDS. XII.1 THE PREPARATION OF A 5,6,8-TRIKETO-9-METHYL-2-OCTALIN2ELEANORE W. J. BUTZ and LEWIS W. BUTZCite this: J. Org. Chem. 1943, 08, 6, 497–499Publication Date (Print):November 1, 1943Publication History Published online1 May 2002Published inissue 1 November 1943https://doi.org/10.1021/jo01194a001RIGHTS & PERMISSIONSArticle Views58Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (236 KB) Get e-Alerts Get e-Alerts
Censored lifetime data in adaptive neural networks. (1996)

This new methodology, in combination with results obtained from previous models which were able to identify the patients most likely to experience such events, now completes the picture by pin-pointing the 'who', as well as the 'when'.
Nucleic Acid-Based Fluorescence Sensors for Detecting Proteins (2005)

We report here development of a rapid, homogeneous, aptamer-based fluorescence assay ("molecular beacons") for detecting proteins. The assay involves protein-induced coassociation of two aptamers recognizing two distinct epitopes of the protein. The aptamers contain short fluorophore-labeled complementary "signaling" oligonucleotides attached to the aptamer by non-DNA linker. Coassociation of the two aptamers with the protein results in bringing the two "signaling" oligonucleotides into proximity, producing a large change of fluorescence resonance energy transfer between the fluorophores. We used thrombin as a model system to provide proof-of-principle evidence validating this molecular beacon design. Thrombin beacon was capable of detecting the protein with high selectivity (also in complex biological mixtures), picomolar sensitivity, and high signal-to-background ratio. This is a homogeneous assay requiring no sample manipulation. Since the design of molecular beacons described here is not limited to any specific protein, it will be possible to develop these beacons to detect a variety of target proteins of biomedical importance.
Identifying drug therapies for plexiform neurofibromas in Neurofibromatosis Type 1 through chemo-genomic analysis (P3.145) (2017)

Characterize the genomic and transcriptomic profile of a panel of human tumor-derived pNF cell lines to explore how genetic background interacts with drug response in NF1 plexiform neurofibormas.
Voluntary exposure of some western‐hemisphere snake and lizard species to ultraviolet‐B radiation in the field: how much ultraviolet‐B should a lizard or snake receive in captivity? (2009)

Abstract Studies of voluntary exposure to ultraviolet‐B (UVB) radiation from the sun in the field were conducted in the southern US and Jamaica for 15 species of lizards and snakes occupying various habitats. Species were sorted into four zones of UVB exposure ranging from a median UV index of 0.35 for zone 1 to 3.1 for zone 4. Guidelines for UVB exposure in captivity of these and species occupying similar light environments are presented. Data for most species were collected during mid‐day during the spring breeding season, which appeared to be the time of maximum exposure. For two species of Sceloporus studied more intensively there was significant variation of exposure among times of the day and among seasons. So, all‐day studies over the entire active season are necessary to fully understand the pattern of natural exposure for a particular diurnal species. Environmental and body temperature and thermoregulation as well as UVB/vitamin D photoregulation influences exposure to UVB. Regressions allowing the inter‐conversion of readings among some meters with different detector sensitivities are presented. Readings of natural sunlight predict the same photobiosynthetic potential for vitamin D as the same reading from artificial sources whose wavelength distribution within the UVB band of the source is comparable to that of sunlight. Research approaches to further increase our understanding of vitamin D and UVB use and requirements for squamate reptiles in captivity are outlined. Zoo Biol 29:317–334, 2010. © 2009 Wiley‐Liss, Inc.
Optical Fiber Sensing Applications: Detection and Identification of Gases and Volatile Organic Compounds (2012)

Optical Fiber Sensing Applications: Detection and Identification of Gases and Volatile Organic Compounds