gebhart/patrepeval huggingface dataset:
Simulation of internal electromagnetic interference for vehicular antenna performance evaluation (2016)

Due to the increasing number of infotainment and safety functions in vehicles, the need for reliable communication link is becoming very critical. A key consideration in providing a reliable link is the antenna performance, which is conventionally evaluated by its efficiency and ability to provide the required coverage upon integration in vehicles. However, modern vehicles are equipped with many electronic devices that emit electromagnetic interference (EMI), which can become the main bottleneck of vehicular antenna performance. In this work, a simulation framework is provided to study the impact of EMI on vehicular antenna performance. Specifically, full-wave car simulations of the coupling of EMI into antennas at the GSM900 band is presented as a case study to demonstrate the important need to address EMI issues in vehicular antenna design and implementation.
[Paper] Deep Reinforcement Learning-based Music Recommendation with Knowledge Graph Using Acoustic Features (2021)

In this study, we propose a new deep reinforcement learning-based music recommendation method with knowledge graphs. With the rapid development of Web services, music-related content posted on platforms, such as YouTube, is increasing dramatically. Conventional recommendation methods based on knowledge graphs have struggled with the cold-start problem caused by a lack of user preference information. The proposed method can solve this problem by introducing acoustic feature edges in the constructed knowledge graph. Furthermore, we realize efficient search using a deep reinforcement learning algorithm on a dense knowledge graph introducing acoustic feature-based edges. The proposed method can make appropriate recommendations even with a small amount of user preference information by learning the optimal action of the agent. We confirm the effectiveness of the proposed method by comparing our method with several conventional and state-of-the-art recommendation methods.
The Factors in L2 Learning Motivation and Their Pedagogical Implications in English Classroom (2006)

Motivation is a powerful affective variable in SLA (Second Language Acquisition), and it has a great influence on L2 (Second Language) learning. L2 learning motivation is affected by language-related factors such as the culture, the community and the value of the L2 and of learning it, learner factors such as self-efficacy, causal attribution, goal orientation etc, and learning-situation-specific factors such as the teacher, the teaching method, the syllabus and so on. These factors have great pedagogical implications in English classroom.
Frontiers of Stochastically Nondominated Portfolios (2003)

We consider the problem of constructing a portfolio of finitely many assets whose returns are described by a discrete joint distribution.We propose mean-risk models that are solvable by linear programming and generate portfolios whose returns are nondominated in the sense of second-order stochastic dominance. Next, we develop a specialized parametric method for recovering the entire mean-risk efficient frontiers of these models and we illustrate its operation on a large data set involving thousands of assets and realizations.
Alternative Splicing of a Specific Cytoplasmic Exon Alters the Binding Characteristics of Murine Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1) (1995)

Platelet/endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a membrane glycoprotein expressed on endothelial cells, platelets, and leukocytes. Analysis of PECAM-1 expression in the developing mouse embryo has revealed the presence of multiple isoforms of murine PECAM-1 (muPECAM-1) that appeared to result from the alternative splicing of exons encoding cytoplasmic domain sequences (exons 10-16) (Baldwin, H. S., Shen, H. M., Yan, H., DeLisser, H. M., Chung, A., Mickanin, C., Trask, T., Kirschbaum, N. E. Newman, P. J., Albelda, S., and Buck, C. A. (1994) Development 120, 2539-2553). To investigate the functional consequences of alternatively spliced muPECAM-1 cytoplasmic domains, L-cells were transfected with cDNA for each variant and their ability to promote cell aggregation was compared. In this assay, full-length muPECAM-1 and all three isoforms containing exon 14 behaved like human PECAM-1 in that they mediated calcium- and heparin-dependent heterophilic aggregation. In contrast, three muPECAM-1 variants, all missing exon 14, mediated calcium- and heparin-independent homophilic aggregation. Exon 14 thus appears to modulate the ligand and adhesive interactions of the extracellular domain of PECAM-1. These findings suggest that alternative splicing may represent a mode of regulating the adhesive function of PECAM-1 in vivo and provides direct evidence that alternative splicing involving the cytoplasmic domain affects the ligand specificity and binding properties of a cell adhesion receptor.
Distributed performance counters (2023)

A plurality of first performance counter modules is coupled to a plurality of processing cores. The plurality of first performance counter modules is operable to collect performance data associated with the plurality of processing cores respectively. A plurality of second performance counter modules are coupled to a plurality of L2 cache units, and the plurality of second performance counter modules are operable to collect performance data associated with the plurality of L2 cache units respectively. A central performance counter module may be operable to coordinate counter data from the plurality of first performance counter modules and the plurality of second performance modules, the a central performance counter module, the plurality of first performance counter modules, and the plurality of second performance counter modules connected by a daisy chain connection.
Mitogenic effect of transforming growth factor-β1 on human ito cells in culture: Evidence for mediation by endogenous platelet-derived growth factor (1993)

We assessed the effect of transforming growth factor-β1 on the proliferation of human Ito cells. Ito cells in their myofibroblastlike phenotype were grown from explants of human liver and were characterized with electron microscopy and positive immunostaining for desmin and smooth muscle α-actin. Transforming growth factor-β1 was mitogenic for human Ito cells whatever the culture conditions, although it was, as previously described, inhibitory of growth for rat Ito cells. The mitogenic effect of transforming growth factor-β1 was likely due to induction of autocrine platelet-derived growth factor chain secretion by Ito cells themselves because (a) the mitogenic effect of transforming growth factor-β1 was blocked by specific platelet-derived growth factor antibodies, (b) transforming growth factor-β1 increased platelet-derived growth factor-A chain messenger RNA expression and platelet-derived growth factor-AA secretion by human Ito cells and (c) human Ito cells expressed the α-type platelet-derived growth factor-A receptor messenger RNA. Exogenous platelet-derived growth factor-AA was also mitogenic for human Ito cells, mimicking the effect of transforming growth factor-β1. Our data suggest that results obtained with rat Ito cells must be extrapolated with caution to human ones. The mitogenic effect of transforming growth factor-β1 on human Ito cells probably has pathophysiological relevance because transforming growth factor-β1 has been demonstrated in vivo at sites of active liver fibrogenesis. (Hepatology 1993;18:137-145).
How effective is alcoholism treatment in the United States? (2001)

About one third of clients remain asymptomatic during the year following a single treatment event. The remaining two thirds show, on average, large and significant decreases in drinking and related problems. This substantial level of improvement in "unremitted" clients tends to be overlooked when outcomes are dichotomized as successful or relapsed.
VHF antenna miniaturization using external non-foster matching circuit (2017)

Electrically small antennas are characterized by large reactance and small radiation resistance. Conventional passive impedance matching is limited by the gain-bandwidth theory which predicts narrow bandwidth characteristics. Furthermore, Wheeler-Chu limitation forecast a very narrow band relative to the size of the small antenna and a high quality factor impedance. Non-Foster circuits can overcome these restrictions and achieve broadband performances by using negative circuit elements. These circuits based on negative impedance converters allow cancelling the antenna's reactance and transforming its frequency-dependent radiation resistance to a constant value over a broad frequency band. In this article a miniaturized antenna using a non-Foster impedance matching circuit is presented. This active external matching circuit allows shifting the resonance frequency of an antenna initially designed at 1100–125 MHz while keeping its original dimension of 7 cm and also extending its relative bandwidth from 10% to 104%. An analytical study is used to design the active impedance matching circuit and to implement it. A prototype is fabricated and experimentally tested. Measurements show that non-Foster circuits can be successfully used to overcome fundamental limitations of electrically small passive antennas in terms of bandwidth even if this gain remains weak. © 2017 Wiley Periodicals, Inc. Microwave Opt Technol Lett 59:986–991, 2017
3D Printing Smart Eyeglass Frames: A Review (2023)

Eyeglasses are typical correctors for refractive error eye disorders. They are commonly placed on frames expected to be stylish and durable. Currently, the consumer demand for sustainable and eco-friendly frames is gaining interest, especially since conventional frame manufacturing methods follow a subtraction of large blocks of wasted scrap material. Additive manufacturing (AM) promises better economic feasibility due to reduced tooling, storage, and material costs, as well as enhanced mechanical properties, by inducing nanomaterials and composites. Moreover, synergism between AM and digital design has led to a rising interest in smart or electronic eyeglass frames. This systematic review assesses commercial eyeglass frames that use standard materials with long-lasting resistance, durability, comfort, and versatility with various materials such as metals and polymers. It also explores the design aspects of these eyeglasses and their correlation with the utilization of artificial intelligence trained computer-aided design software. Beyond the appealing eyeglass frame technology, a review of smart frame design, in which electronic sensors and chips are embedded, is also included. Furthermore, this review comprises various applications for 3D printing of frames including commercial and biomedical applications. Other reviewed topics include the side effects, health risks, shortcomings of AM techniques and materials, and void formation inside the matrix that propagates fatigue and shrinkage or density change during solidification.
Computer-guided immediate provisionalization of anterior multiple adjacent implants: surgical and prosthodontic rationale. (2007)

Immediate implant restoration has gained popularity in recent years due in part to technological advancements that use computed tomographic images to simulate the actual clinical situation. This computer-assisted simulation enables clinicians to develop a comprehensive treatment plan that can be precisely executed in a timely manner. In the aesthetic zone, however, a successful outcome requires more than merely accurate implant placement. This article discusses the significance of site development for aesthetic implant restoration and describes a computer-guided immediate pro visionalization procedure and its surgical and prosthodontic rationale
Phenotypic variability in monozygotic twins with neurofibromatosis 2 (1996)

Mutations in the neurofibromatosis 2 (NF2) tumor suppressor gene on chromosome 22q12 cause a clinically variable autosomal dominant syndrome characterized by bilateral vestibular schwannomas (VSs), other nervous system tumors, and early onset lenticular cataracts. We studied three pairs of monozygotic (MZ) twins with NF2, all with bilateral VSs, to separate genetic from nongenetic causes of clinical variability. The evaluation included gadolinium-enhanced high-resolution magnetic resonance imaging of the head and spine, neuro-ophthalmic examination with slit lamp, physical examination, and zygosity testing with microsatellite markers. Each MZ pair was concordant for general phenotypic subtype (mild or severe) and often for the affected organ systems. However, the MZ pairs were discordant for some features of disease presentation or progression. For example, all three pairs were discordant for presence or type of associated cranial tumors. We hypothesize that phenotypic differences between NF2 MZ twins are at least partly due to stochastic processes, such as the loss of the second NF2 allele or alleles of other genes. © 1996 Wiley-Liss, Inc.
Variant influenza virus hemagglutinin that induces fusion at elevated pH (1986)

The hemagglutinin (HA) glycoprotein of influenza virus performs two critical roles during infection: it binds virus to cell surface sialic acids, and under mildly acidic conditions it induces fusion of the virion with intracellular membranes, liberating the genome into the cytoplasm. The pH dependence of fusion varies for different influenza virus strains. Here we report the isolation and characterization of a naturally occurring variant of the X31 strain that fuses at a pH 0.2 units higher than the parent strain does and that is less sensitive to the effects of ammonium chloride, a compound known to elevate endosomal pH. The bromelain-solubilized ectodomain of the variant HA displayed a corresponding shift in the pH at which it changed conformation and bound to liposomes. Cloning and sequencing of the variant HA gene revealed amino acid substitutions at three positions in the polypeptide. Two substitutions were in antigenic determinants in the globular region of HA1, and the third occurred in HA2 near the base of the molecule. By using chimeric HA molecules expressed in CV-1 cells from simian virus 40-based vectors, we demonstrated that the change in HA2 was solely responsible for the altered fusion phenotype. This substitution, asparagine for aspartic acid at position 132, disrupted a highly conserved interchain salt bridge between adjacent HA2 subunits. The apparent role of this residue in stabilizing the HA trimer is consistent with the idea that the trimer dissociates at low pH. Furthermore, the results demonstrate that influenza virus populations contain fusion variants, raising the possibility that such variants may play a role in the evolution of the virus.
SIC: an intracerebral radiosensitive probe for in vivo neuropharmacology investigations in small laboratory animals: prototype design, characterization, and in vivo evaluation (2002)

Several high-resolution tomographs dedicated to small animal imaging are presently under development. However, these devices are limited by two major drawbacks: their cost is high and they require animal anaesthesia and immobilization, thus restricting the scope of investigations. Therefore, we have developed SIC (French acronym for "Sonde IntraCerebrale") a low-cost beta microprobe for measuring local radioactivity in awake, freely moving animals. Besides good sensitivity, SIC offers the advantage of a high temporal resolution, a major asset for in vivo measurements of tracer kinetics. Furthermore, SIC can be readily combined with existing techniques such as electrophysiology, microdialysis, voltammetry and magnetic resonance imaging, providing simultaneous complementary information on cerebral function. We present here the design, manufacture, and evaluation of a SIC prototype. In vitro evaluation using a beaker filled with a homogenous aqueous solution of [/sup 18/F]-fluorodeoxyglucose (/sup 18/F-FDG) confirmed our Monte Carlo simulation results in terms of sensitivity and detection volume. Further in vivo studies on rats with two probes implanted in the brain validated the use of SIC to measure the local concentration of radio-labeled molecules in rat brain with a high temporal resolution.
Acetylcholinesterase function in apoptotic retina pigment epithelial cells induced by H2O2. (2013)

AChE is weakly expressed in normal human RPE cells. Stimulation with H2O2 caused the stable increase of AChE expression in RPE cells, which may indicate that AChE may be an important role in AMD.
A hereditary immunodeficiency characterized by CD8+ T lymphocyte deficiency and impaired lymphocyte activation (1992)

An unusual form of severe combined immunodeficiency in children from two different families was associated with absence of CD8+ T lymphocytes and normal numbers of CD4+ T lymphocytes that did not respond to stimulation by non-specific mitogens, specific antibodies against T cell receptor or specific antigens. The defect in the CD4+ cells was bypassed by activating agents which are independent of the T cell receptor. The combination of an activation defect and selective depletion of CD8+ T lymphocytes suggests that the defective pathway is important in the differentiation of immature thymocytes as well as the proliferation of mature lymphocytes.
Characterization of polysilicon contacts by photoconductance measurements (2003)

The confinement property of polysilicon contacts, leading to storage of minority carriers, has been studied using the photoconductivity technique. Steady-state and transient optical measurement show a considerable increase of stored carriers by these contacts. A model has been developed that allows the extraction of contact parameters.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Mouse plasmacytoma growth in vivo: enhancement by interleukin 6 (IL-6) and inhibition by antibodies directed against IL-6 or its receptor. (1990)

Murine plasmacytomas show a striking dependence on interleukin 6 (IL-6) for their growth in vitro. Here, we present evidence suggesting that IL-6 also plays an essential role in the in vivo development of these tumors. This conclusion is based on the finding that the tumorigenicity of an IL-6-dependent plasmacytoma cell line was increased approximately 100-fold on transfection with an IL-6 expression vector, whereas it was inhibited in animals treated with monoclonal antibodies capable of blocking the binding of IL-6 to its receptor. Injection of these antibodies 1 d before tumor challenge protected greater than 50% of the mice and retarded tumor growth in all animals. Tumors arising in antibody-treated mice retained their IL-6 dependence in vitro, suggesting that the level of protection could be improved if stronger IL-6 antagonists were available.
Digital image source coder forensics via intrinsic fingerprints (2009)

Recent development in multimedia processing and network technologies has facilitated the distribution and sharing of multimedia through networks, and increased the security demands of multimedia contents. Traditional image content protection schemes use extrinsic approaches, such as watermarking or fingerprinting. However, under many circumstances, extrinsic content protection is not possible. Therefore, there is great interest in developing forensic tools via intrinsic fingerprints to solve these problems. Source coding is a common step of natural image acquisition, so in this paper, we focus on the fundamental research on digital image source coder forensics via intrinsic fingerprints. First, we investigate the unique intrinsic fingerprint of many popular image source encoders, including transform-based coding (both discrete cosine transform and discrete wavelet transform based), subband coding, differential image coding, and also block processing as the traces of evidence. Based on the intrinsic fingerprint of image source encoders, we construct an image source coding forensic detector that identifies which source encoder is applied, what the coding parameters are along with confidence measures of the result. Our simulation results show that the proposed system provides trustworthy performance: for most test cases, the probability of detecting the correct source encoder is over 90%.
In-memory computing with memristive devices (2020)

L’industria microelettronica e stata guidata dalla legge di Moore che ha portato a una robusta collaborazione tra innovazione tecnologica e commerciale per aumentare esponenzialmente le prestazioni dei microprocessori. Questo e stato reso possibile grazie alla riduzione nella dimensione dei dispositivi elettronici e la conseguente possibilita di inserirne di piu in un’area fissata. Purtroppo, diversi problemi stanno rallentando il miraggio di una crescita eterna. Tra questi, l’eccessiva dissipazione di calore dei componenti ultra-scalati e i limiti fisici nel proseguire lo scaling con tecniche convenzionali. Inoltre nelle architetture tradizionali di tipo Von Neumann la maggior parte dell’energia e del tempo viene speso per trasferire dati dalla memoria al processore e viceversa, risultando in un collo di bottiglia detto Von Neumann bottleneck, che viene ulteriormente enfatizzato nella nostra epoca governata da un enorme scambio di dati. 
Per superare questi limiti, da un lato devono essere sviluppati nuovi ed efficienti dispositivi nanoelettronici e dall’altro bisogna realizzare architetture innovative in grado di favorire un calcolo piu vicino alla memoria. Il cervello umano viene utilizzato come fonte d’ispirazione per realizzare architetture dove memoria e calcolo avvengono nella stessa unita. Gli ingegneri neuromorfici cercano di imitare il comportamento del cervello umano per arrivare a sistemi computazionale ad alte prestazioni energetico.
Memorie emergenti come Resistive Random Access Memories (RRAM) e Phase Change Memories (PCM) hanno attratto l’interesse dell’industria come un compatto sostituto delle attuali tecnologie di memoria. Inoltre, questi nuovi dispotici offrono la possibilita di programmazione multilivello e neuromorfico.
Esplorare innovative architetture in memoria e bio-ispirate con dispositivi di memoria emergenti e l’obiettivo della dissertazione di dottorato. Questi concetti sono stati dimostrati sperimentalmente in architetture hardware innovative.
Fast list Viterbi decoding and application for source-channel coding of images (2003)

A list Viterbi algorithm (LVA) finds the n best paths in a trellis. We propose a new implementation of the tree-trellis LVA. Instead of storing all paths in a single sorted list, we show that it is more efficient to use several lists, where all paths of the same list have the same metric. For an integer metric, both the time and space complexity of our implementation are linear in n. Experimental results show that our implementation is much faster than all previous LVAs. This allows us to consider a large number of paths in acceptable time, which significantly improves the performance of a popular progressive source-channel coding system that protects embedded data with a concatenation of an outer error detecting code and an inner error correcting convolutional code.
New routes to selectively methylated benzimidazoles (1994)

Abstract The use of intermediate benzotriazol‐l‐yl derivatives simplified the procedures for the preparation of 5‐methoxy‐l‐methylbenzimidazole and 6‐methoxy‐l‐methylbenzimidazole starting from 4‐methoxy‐2‐nitro‐aniline. This strategy represents a novel and potentially general method for synthesis of 5‐ and 6‐substituted‐l‐methylbenzimidazoles from 4‐substituted anilines. Preparation of l‐methyl‐5‐nitrobenzimidazole by reaction of 2‐chloro‐5‐nitroaniline with methylamine and condensation of the obtained diamine with formic acid represents a special case.
Which Bacterial Biofilm Exopolysaccharide Is Preferred, Psl or Alginate? (2013)

Published ahead of print 15 February 2013



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