gebhart/patrepeval huggingface dataset:
Abstract 81: B Lymphocytes Trigger MCP3-Dependent Mobilization of Monocytes and Promote Adverse Ventricular Remodeling After Myocardial Infarction (2012)

Leukocyte infiltration in ischemic areas is a hallmark of myocardial infarction, and persistent infiltration of innate immune cells, such as neutrophils and Ly6Chi monocytes, has been shown to promote adverse cardiac tissue remodeling. However, little is known regarding the role of mature B lymphocytes, which play a crucial role in the activation of the inflammatory response in several immune-mediated diseases. Here, we hypothesized that B lymphocytes might modulate the inflammatory response and affect the immune-dependent adverse cardiac remodeling. In a mouse model of myocardial infarction, cardiac B lymphocytes levels peaked at day 5 after the onset of infarction. Of interest, treatment with a CD20-specific monoclonal antibody decreased circulating and infiltrating B cell numbers (p=0.0008 and p=0.0002 vs control), reduced infarct size and post-ischemic immunoinflammatory response, and improved cardiac function (p=0.02 vs control) assessed by echocardiography. Intriguingly, B cell depletion was associated with an impairment of Ly6Chi monocytes mobilization from bone marrow (p=0.02 vs control), leading to reduced levels of circulating and infiltrating cardiac monocytes. The acute infarction led to transient increase of both MCP-1 and MCP-3 levels. Interestingly, B cell depletion was associated with a significant and selective reduction of MCP-3 (p=0.03 vs control) but did not alter MCP-1 levels (p=0.11). Cultured activated B cells released MCP-3 and treatment with a neutralizing MCP-3 antibody abrogated B lymphocytes-induced migration of cultured monocytes. Finally, transfer of B cell-depleted splenocytes into Rag1 -/- mice improved cardiac function after myocardial infarction compared to the transfer of non-depleted splenocytes (p=0.005). This effect was abrogated after re-supplementation with B lymphocytes isolated from wild-type mice (p=0.0007) but not from MCP-3-deficient animals (p=0.7008). In conclusion, we show that following acute myocardial infarction, B lymphocytes, trigger an MCP-3-dependent mobilization of Ly6Chi monocytes from the bone marrow to the blood, leading to their recruitment into the injured myocardium and to exacerbation of tissue inflammation, thereby promoting adverse cardiac remodeling.
Supplemental Figure 3 from Histone Deacetylase Inhibitor Entinostat Inhibits Tumor-Initiating Cells in Triple-Negative Breast Cancer Cells (2023)

&lt;p&gt;Supplemental Figure 3. Effect of ENT on mammosphere formation&lt;/p&gt;
The Theory of the Adsorption Monolayer with Lateral Intermolecular Interaction and Its Application to Aqueous Alcohol Solutions (1977)

Abstract A theoretical relation between the fractional adsorption amount, θ, and the concentration, C, taking account of the lateral interaction between the adsorbed molecules is used to integrate the Gibbs equation, and the relation between the surface pressure, F, and the molecular area, A, is derived. Since the equation does not contain the parameter, k0, related to the strength of adsorption, it is concluded that there is no substantial difference between the adsorption monolayers and the insoluble monolayers. The relation between F and C is also derived and compared with the experimental data for normal alcohols. The standard affinity of adsorption, −Δμ0, and the energy of lateral interaction, ε, increased linearly with the number of carbon atoms of the alcohols, n. Finally, it has been shown that the experimental data can be explained well with the theoretical equation presented here, but not with Szyszkowski’s, the latter being derived for negligible lateral interaction.
Robotic Radiosurgery With Noncylindrical Collimators (1997)

AbstractIn radiosurgery, a moving beam of radiation acts as an ablative surgical instrument. Conventional systems for radiosurgery use a cylindrical radiation beam of fixed cross section. The radiation source can be moved only along simple, standardized paths. A new radiosurgical system based on a six-degree-of-freedom robotic arm has been developed to overcome limitations of conventional systems. We address the following question: Can dose distributions generated by robotic radiosurgery be improved by using noncylindrical radiation beams? This includes static noncylindrical collimators and collimators of adaptable cross section. Geometric methods for planning the shape of the beam in addition to planning beam motion are developed. Design criteria considered in this context are treatment time, radiation penumbra, and transparency of interactive treatment planning. An experimental evaluation compares distributions generated with our new radiosurgical system using cylindrical beams to distributions generated with beams of adaptable, noncylindrical shapes.Key Words: medical roboticsradiation therapyradiosurgeryimage guided surgerygeometric reasoning
Formulas for stress, strain, and structural matrices (1995)

From the Publisher:
This is a reference source for strength of material formulas for the analysis and design of structural members and mechanical elements. Allows efficient static, stability and dynamic analyses of beams, bars, plates and shells with very general mechanical or thermal loading. The range of solutions includes arbitrary geometries and loadings.
ATG5 and ATG7 induced autophagy interplays with UPR via PERK signaling (2019)

ATG5 and ATG7 connect autophagy with ER stress through PERK signaling. The protective effect of ATG5/7 overexpression on chondrocyte survival relys on PERK signaling. The effect of siPERK and siNrf2 on the cytoprotective effect of ATG5/7 are of synergism, while the effect of siPERK and siATF4 are of antagonism. PERK signal may be the pivot for autophagy, ER homeostasis and ER-phagy in chondrocyte.
Design and Experimental Validation of a Switchable Frequency Selective Surface with Incorporated Control Network (2023)

Tunable/switchable devices are more and more required in modern communication systems. However, the realization of the tuning requires the presence of active devices, which in turn must be biased. The current paper comes up with a solution for designing and experimentally validating such a switchable Frequency Selective Surface. Two different metallic structures are simulated and measured, having incorporated the same topology control network (CN). In this scenario, the main innovation of this paper is the presence of the feeding part, namely the control network. In this work, the main FSS structure is flanked by three parallel CN microstrip lines and several via holes that allow biasing the active elements, namely PIN diodes. The switchability of the proposed structure is achieved through PIN diodes, whose bias determines the values of the elements in the equivalent circuit. At different biases, the response of the FSS changes accordingly. From all possible values of the bias, the extreme cases when the diodes act as (almost) short- and open-circuits are considered in the submitted manuscript for the sake of brevity. These cases are modeled by the main and cut-slot structures, respectively. The proposed structures have been evaluated using electromagnetic simulation and implemented on an FR4 substrate having a thickness of 1.58 mm. With the periodicity of the square-shaped unit cell of 18 mm edge length, different filtering bands are obtained below 12 GHz. Another novelty that has received very little consideration in the existing literature is the use of a finite array of unit cells instead of an infinite one. And finally, tests in an anechoic chamber have proved that there is a good agreement between practical and simulation results and also demonstrated the proper performance of the devices for wide angular incidence for both TE and TM polarizations.
Efficient removal of pentachlorophenol from aqueous solution by 4-tert-butylcalix[8]arene modified thermally sensitive hydrogels (2018)

We prepared poly(<i>N</i>-isopropylacrylamide-<i>co</i>-4-<i>tert</i>-butylcalix[8]arene) (PNIPAM-TBCX) hydrogels by copolymerization of <i>N</i>-isopropylacrylamide (NIPAM) with 4-<i>tert</i>-butylcalix[8]arene (TBCX) to capture hazardous pentachlorophenol (PCP) from aqueous solution. Adsorption experiments showed that the adsorption capacities of PNIPAM-TBCX hydrogels reached 1.96, 2.08 and 2.02 mg PCP per 1 g of hydrogel, while the molar percentage ratio of TBCX in the hydrogels was as low as 0.5%, 0.7% and 1%. The equilibrium adsorption of PCP on the hydrogels was studied using different adsorption models. In addition, the PNIPAM-TBCX hydrogel still retained its performance when regenerated several times by immersing in water at 323 K.
Controller design for flexible, distributed parameter mechanical arms via combined state space and frequency domain techniques (1982)

The potential benefits of the ability to control more flexible mechanical arms are discussed. A justification is made in terms of speed of movement. A new controller design procedure is then developed to provide this capability. It uses both a frequency domain representation and a state variable representation of the arm model. The frequency domain model is used to update the modal state variable model to insure decoupled states. The technique is applied to a simple example with encouraging results.
Dispersion of graphite nanosheets in a polymer matrix and the conducting property of the nanocomposites (2001)

Abstract Poly(methyl methacrylate)(PMMA)/expanded graphite composite has been made via an in situ polymerization of methyl methacrylate(MMA) in the presence of expanded graphite obtained by rapid heating of the graphite intercalation compound (GIC). The composite was then blended with poly(vinyl chloride) (PVC) to form an electrically conducting composite. SEM, TEM and XRD showed that the graphite had been dispersed throughout the polymer matrix in the form of nanosheets with thicknesses of about 20 nm. The resulting composite showed excellent electrical conductivity despite a low concentration of graphite. The transition from an electrical insulator to an electrical semiconductor for the composite occurred when the graphite content was 3.5 wt%, much lower than that of conventional conducting polymer composites. Conductivity reached a maximum of 10 −4 s/cm at a graphite concentration of 5.0 wt%. This improvement of conductivity could be attributed to the high aspect ration (width‐to‐thickness) of the graphite nanosheets dispersed in the polymer matrix.
Tecnologías <i>big data</i> para análisis y recuperación de imágenes web (2014)

This paper addresses web analytics from an images perspective, using big data technologies. Images are increasingly present on the web, and therefore any web analysis must consider them. The huge volume of available images requires the use of large computation infrastructures in order to generate this kind of analysis, as well as specific computer vision algorithms. Big data technologies are discussed that can be used for large-scale image processing. In addition, a novel distributed algorithm is proposed that can efficiently retrieve images from an online collection at low computational cost. This algorithm can be used in web analysis or future research requiring detailed image study, without requiring any special hardware.
A Theoretical Model and Study of Weighted MCTF Residual Energy (2006)

This paper presents a theoretical model and study of the impact of the weighted motion-compensated residual energy on the coding efficiency of motion-compensated temporal filtering (MCTF) when MCTF update steps are performed at both encoder and decoder sides and when update steps are executed at the encoder side only. We observe that in the presence of the uncompensated quantization errors due to the MCTF open-loop structure, the decoder must attempt to recover the update weight used by the encoder and this non-linear transform may contribute to the possible magnification of the quantization errors. We apply our analysis to the joint scalable video model (JSVM) 2.0. It is demonstrated that performing the MCTF update step at the decoder side does not contribute significantly to the coding efficiency, except at high spatial-temporal resolutions with high bit rates. This further justifies theoretically the elimination of the MCTF update step as a normative tool for temporal scalability in the current H.264/AVC scalable extension development
Now You See It, Now You Don't: Ethnography and Selective Visibility in the Technology Sector (2008)

As ethnographers practicing within an engineering driven industry, we often struggle with visibility and its effects. Exposing the methodological and technical underpinnings of ethnographic practice can bring us closer to the teams we work with, but it can also draw attention to the ways that engineering and anthropology clash. In this brief paper we describe the rationale for deliberate and highly selective visibility in our engineering‐driven workplace. We will draw on our experience as anthropologists “embedded” in teams of engineers to discuss our own claims to authority and examine how legitimacy is conferred upon ideas and actions in a technology‐driven environment.
Expansive Duraplasty – Simple Technique with Promising Results in Complete Cervical Spinal Cord Injury (2022)

Durotomy and duraplasty may be offered in all patients with complete spinal cord injury who are undergoing instrumentation.
Model-based local density sharpening of cryo-EM maps (2017)

Atomic models based on high-resolution density maps are the ultimate result of the cryo-EM structure determination process. Here, we introduce a general procedure for local sharpening of cryo-EM density maps based on prior knowledge of an atomic reference structure. The procedure optimizes contrast of cryo-EM densities by amplitude scaling against the radially averaged local falloff estimated from a windowed reference model. By testing the procedure using six cryo-EM structures of TRPV1, β-galactosidase, γ-secretase, ribosome-EF-Tu complex, 20S proteasome and RNA polymerase III, we illustrate how local sharpening can increase interpretability of density maps in particular in cases of resolution variation and facilitates model building and atomic model refinement.
High-fidelity colour reproduction for high-dynamic-range imaging (2010)

The aim of this thesis is to develop a colour reproduction system for high-dynamic-range (HDR)&#13;\nimaging. Classical colour reproduction systems fail to reproduce HDR images because current characterisation&#13;\nmethods and colour appearance models fail to cover the dynamic range of luminance&#13;\npresent in HDR images. HDR tone-mapping algorithms have been developed to reproduce HDR&#13;\nimages on low-dynamic-range media such as LCD displays. However, most of these models have&#13;\nonly considered luminance compression from a photographic point of view and have not explicitly&#13;\ntaken into account colour appearance. Motivated by the idea to bridge the gap between crossmedia&#13;\ncolour reproduction and HDR imaging, this thesis investigates the fundamentals and the&#13;\ninfrastructure of cross-media colour reproduction. It restructures cross-media colour reproduction&#13;\nwith respect to HDR imaging, and develops a novel cross-media colour reproduction system for&#13;\nHDR imaging. First, our HDR characterisation method enables us to measure HDR radiance values&#13;\nto a high accuracy that rivals spectroradiometers. Second, our colour appearance model enables us&#13;\nto predict human colour perception under high luminance levels. We first built a high-luminance&#13;\ndisplay in order to establish a controllable high-luminance viewing environment. We conducted a&#13;\npsychophysical experiment on this display device to measure perceptual colour attributes. A novel&#13;\nnumerical model for colour appearance was derived from our experimental data, which covers the&#13;\nfull working range of the human visual system. Our appearance model predicts colour and luminance&#13;\nattributes under high luminance levels. In particular, our model predicts perceived lightness&#13;\nand colourfulness to a significantly higher accuracy than other appearance models. Finally, a complete&#13;\ncolour reproduction pipeline is proposed using our novel HDR characterisation and colour&#13;\nappearance models. Results indicate that our reproduction system outperforms other reproduction&#13;\nmethods with statistical significance. Our colour reproduction system provides high-fidelity colour&#13;\nreproduction for HDR imaging, and successfully bridges the gap between cross-media colour reproduction&#13;\nand HDR imaging.
Toxoplasma gondii seropositivity associated to peri-urban living places in pregnant women in a rural area of Buenos Aires province, Argentina (2019)

Infection with <i>Toxoplasma gondii</i> is very common in humans throughout the world, the intake of raw or undercooked meat with tissue cysts and fruits, vegetables and water contaminated with parasite oocysts being the main routes of infection. Here, we analyzed the seroprevalence of <i>anti</i>-<i>T. gondii</i> antibodies in pregnant females (age 13-44 years; n = 920) between April 2014 and December 2017 from Chascomús (Argentina), a city immersed in a rural area. Altogether 320 tested positive for immunoglobulin G antibodies, yielding an overall seroprevalence of 34.8% (CI 95%: 31.7-37.9). No association was observed between seropositivity and age. In addition, by using the QGIS 3.2.1 software we analyzed the geographical distribution of 769 (83.6%) pregnant females in two main areas of the city: Urban (n = 157) and Peri-urban (n = 612) with a seroprevalence of 26.8% (CI 95%: 19.8-33.7) and 36.4% (CI 95%: 32.6-40.3) respectively, and this difference was statistically significant (p = 0.023). Furthermore, we assessed through a questionnaire survey, between April 2016 to December 2017, possible risk factors such as activity (urban and rural), home water supply, animal husbandry, presence of cats as pets, gardening and consumption of meat and its derivatives (pork, sheep meat and sausages) and their frequencies (consumption per week), not finding significant association with seropositivity. Significant differences was found when the seroprevalence was analyzed between the urban and peri-urban neighborhoods of the city of Chascomús. The higher seroprevalence in peri-urban neighborhoods could be due to an unfavorable socioeconomic situation and/or to undeveloped peri-urban environments, which is a risk factor that should be taken into account when planning the health care of pregnant females.
Single transient radiation damage to optical fibers from a fission source (1983)

Radiation damage on optical fibers has been extensively studied with continuous radiation sources1 and pulsed x-ray2 and electron sources.3 None of these studies has a source which represents the temporal and spectral radiation history from a nuclear device.
Molecular Mapping of Nuclear Male Sterility Genes in Sunflower (2005)

Nuclear male sterility (NMS) is a useful tool for sunflower ( Helianthus annuus L.) breeding and genetics programs. A clear understanding of the genetics of NMS at the molecular level and the identification of linked molecular markers will greatly facilitate breeding for this trait. P21 is an inbred line carrying the single gene Ms 11 controlling NMS, and NMS801 and NMS373 are two inbred lines with the NMS gene Ms 10 The objectives of this study were to (i) identify molecular markers linked with the Ms 10 and the Ms 11 NMS genes, and (ii) place these genes on the genetic map of sunflower. Three F 2 and a BC 1 F 1 mapping populations developed from crosses between the male‐sterile (MS) lines P21, NMS801, and NMS373, and male‐fertile (MF) (wild‐type) lines were scored for fertility/sterility. The NMS801 and NMS373 populations segregated for Ms 10 and T, a tightly linked anthocyanin pigment locus. The P21 populations segregated for Ms 11 These populations were then genotyped with restriction fragment length polymorphism (RFLP), simple sequence repeat or microsatellite (SSR), and insertion–deletion polymorphism (INDEL) markers, and four genetic maps comprising 14 to 17 linkage groups (LGs) were constructed for each population. The Ms 10 and T genes mapped to LG 11, while the Ms 11 gene mapped to LG 8. Four SSR markers (ORS697, ORS1214, ORS686, and CRT162) and the phenotypic marker locus T cosegregated and were tightly linked to Ms 10 at a genetic distance of less than 1 cM. The Ms 11 gene locus was flanked by the SSR markers MS925 and ORS536 at genetic distances of 3.8 and 4.1 cM, respectively. The availability of tightly linked polymerase chain reaction based markers and the location of NMS genes on the sunflower genetic map will be useful for marker‐assisted selection (MAS) in sunflower breeding programs and provides a basis for the physical mapping and positional cloning of these genes.
Uni-, Bi-, and Tri-Directional Wetting Caused by Nanostructures with Anisotropic Surface Energies (2012)

Wetting is a pervasive phenomenon that governs many natural and artificial processes. Asymmetric wetting along a single axis, in particular, has generated considerable interest but has thus far been achieved only by the creation of structural anisotropy. In this paper, we report that such directional wetting can also be achieved by anisotropically coating nanostructure surfaces with materials that modify the nanostructure surface energy, a phenomenon that has not been observed in natural or artificial systems thus far. Moreover, by combining this newfound chemical influence on wetting with topographic features, we are able to restrict wetting in one, two and three directions. A model that explains these findings in terms of anisotropy of the pinning forces at the triple phase contact line is presented. Through the resulting insights, a flexible method for precise control of wetting is created.
Eutectic Ga-In liquid metal based flexible capacitive pressure sensor (2016)

A novel flexible pressure sensor has been successfully developed for detecting varying applied pressures. Polydimethylsiloxane (PDMS) and eutectic gallium indium (EGaIn) based liquid metal, as the conductive electrodes, were used to fabricate the sensor. The sensor was designed with four capacitors (C1, C2, C3 and C4) which were formed by overlapping the liquid metal based electrodes. The capability of the fabricated capacitive pressure sensor was investigated by applying varying pressures. A maximum average capacitance change of 10.14%, 11.56%, 11.57% and 11.82% was obtained for C1, C2, C3 and C4 respectively, when pressures were applied from 0.25 MPa to 1.1 MPa. A sensitivity of 0.11%/MPa and correlation coefficient of 0.9875 was obtained for the fabricated pressure sensor. The results thus demonstrated the potential of using liquid metal based electrodes for the development of flexible pressure sensors.