gebhart/patrepeval huggingface dataset:
The Synthesis of Fluorine-containing Olefins (1953)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Synthesis of Fluorine-containing OlefinsE. T. McBee, O. R. Pierce, and M. C. ChenCite this: J. Am. Chem. Soc. 1953, 75, 10, 2324–2326Publication Date (Print):May 1, 1953Publication History Published online1 May 2002Published inissue 1 May 1953https://pubs.acs.org/doi/10.1021/ja01106a011https://doi.org/10.1021/ja01106a011research-articleACS PublicationsRequest reuse permissionsArticle Views85Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Green-color EL device with sputtered ZnS:TbOF thin films (2003)

A green-color AC electroluminescent device with ZnS:TbOF thin films has been fabricated by diode RF-sputtering. The effect of oxygen doping and sputtering conditions on the device performance has been investigated. It has been found that the performance improvement can be achieved by codoping oxygen into the active layers.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
PriMPSO: A Privacy-Preserving Multiagent Particle Swarm Optimization Algorithm (2022)

Centralized particle swarm optimization (PSO) does not fully exploit the potential of distributed or parallel computing and suffers from single-point-of-failure. Particularly, each particle in PSO comprises a potential solution (e.g., traveling route and neural network model parameters) which is essentially viewed as private data. Unfortunately, previously neither centralized nor distributed PSO algorithms fail to protect privacy effectively. Inspired by secure multiparty computation and multiagent system, this article proposes a privacy-preserving multiagent PSO algorithm (called PriMPSO) to protect each particle's data and enable private data sharing in a privacy-preserving manner. The goal of PriMPSO is to protect each particle's data in a distributed computing paradigm via existing PSO algorithms with competitive performance. Specifically, each particle is executed by an independent agent with its own data, and all agents jointly perform global optimization without sacrificing any particle's data. Thorough investigations show that selecting an exemplar from all particles and updating particles through the exemplar are critical operations for PSO algorithms. To this end, this article designs a privacy-preserving exemplar selection algorithm and a privacy-preserving triple computation protocol to select exemplars and update particles, respectively. Strict privacy analyses and extensive experiments on a benchmark and a realistic task confirm that PriMPSO not only protects particles' privacy but also has uniform convergence performance with the existing PSO algorithm in approximating an optimal solution.
Myocardial Coagulation by Intraoperative Nd:YAG Laser Ablation and Its Dependence on Blood Perfusion (1994)

To investigate whether the efficacy of intraoperative laser ablation therapy is affected by myocardial blood perfusion, we irradiated 11 canine hearts through the epicardium with a Nd:YAG laser (10, 20, and 30 J/mm2) using air as the medium. Compared coagulated myocardial depth, width, and volume obtained in the red beating heart was compared with those in the white nonbeating heart infused with 0 degrees C saline (cardioplegic model) via the coronary artery. Histologically, the macro- and microscopical findings were very similar. At each level of energy, the width and volume of red myocardium coagulated were significantly larger than those of white myocardium (P < 0.01). At 30 J/mm2, the depth of coagulation of red myocardium was significantly larger than that of white myocardium (P < 0.01). The coagulated volume of the white myocardium was about 60% of that of the red myocardium. Nd:YAG laser energy was absorbed by blood (red color = hemoglobin), and more energy was transferred in the higher temperature myocardium. During intraoperative Nd:YAG laser ablation, the presence of blood perfusion in cardiac tissue is thought to be an important factor affecting safe irradiation.
Ultraviolet radiation—an incisive and versatile tool (1981)

The growth in the use of ultraviolet and soft x-ray synchrotron radiation has been remarkable in the past decade. The 1970s saw the number of worldwide scientific and technological users of ultraviolet and x-ray synchrotron radiation increase from fewer than perhaps twenty to well over a thousand. In a single decade, an unwanted byproduct of high-energy electron storage machines has turned into the driving force for building a new generation of electron storage rings designed specifically as radiation sources. (See the article by Ednor Rowe, on page 28.) Several new machines with electron energies of 700–1000 MeV are being constructed specifically as sources of ultraviolet and soft x-ray radiation in the regions below about 1000 eV (above about 12 Å in wavelength).
Depletion region in thermally poled fused silica (2000)

The depletion-layer width and the recorded electric field in thermally poled fused silica are investigated experimentally as a function of the applied voltage. The depletion-layer width is observed to vary linearly with the poling voltage. The average electric field recorded in the depletion region was found to be (5.3±0.3)×108 V/m for all samples, independently of the poling voltage.
Parallelizing tightly nested loops (2002)

Presents a new technique to parallelize nested loops at the statement level. It transforms sequential nested loops, either vectorizable or not, into parallel ones. Previously, the wavefront method was used to parallelize non-vectorizable nested loops. However, in order to reduce the complexity of parallelization, the wavefront method regards an iteration as an unbreakable scheduling unit and draws parallelism through iteration overlapping. The technique takes a statement rather than an iteration as the scheduling unit and exploits parallelism by overlapping the statements in all dimensions. In the paper, the authors show how this finer grain parallelization can be achieved with reasonable computational complexity, and the effectiveness of the resulting method in exploiting parallelism.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Differential contribution of immune effector mechanisms to cortical demyelination in multiple sclerosis (2017)

Cortical demyelination is a widely recognized hallmark of multiple sclerosis (MS) and correlate of disease progression and cognitive decline. The pathomechanisms initiating and driving gray matter damage are only incompletely understood. Here, we determined the infiltrating leukocyte subpopulations in 26 cortical demyelinated lesions of biopsied MS patients and assessed their contribution to cortical lesion formation in a newly developed mouse model. We find that conformation-specific anti-myelin antibodies contribute to cortical demyelination even in the absence of the classical complement pathway. T cells and natural killer cells are relevant for intracortical type 2 but dispensable for subpial type 3 lesions, whereas CCR2<sup>+</sup> monocytes are required for both. Depleting CCR2<sup>+</sup> monocytes in marmoset monkeys with experimental autoimmune encephalomyelitis using a novel humanized CCR2 targeting antibody translates into significantly less cortical demyelination and disease severity. We conclude that biologics depleting CCR2<sup>+</sup> monocytes might be attractive candidates for preventing cortical lesion formation and ameliorating disease progression in MS.
Lymphokine Production in Autoimmunity: Usefulness of mRNA Assays (1987)

Recent studies have emphasized the similarity of autoimmune responses to those occuring against extrinsic antigens. In autoimmune diseases such as Graves’ disease, T lymphocytes are activated by tissue cells expressing HLA class II antigens presenting their autoantigens to autoreactive T cells. More commonly antigen presenting cells expressing HLA class II activate T cells recognizing extrinsic antigens. Since it has been amply demonstrated that class II expression is regulated by lymphokines such as Interferon γ, it is apparent that the regulation of lymphokine production in autoimmunity needs to be understood.
Reaction Bomb for Use at Elevated Temperatures and Pressures (1957)

First Page
Synergism of ursolic acid and cisplatin promotes apoptosis and enhances growth inhibition of cervical cancer cells via suppressing NF-κB p65 (2017)

The combination of UA with DDP could more effectively inhibit SiHa cells proliferation and facilitate cell apoptosis through suppressing NF-κB p65.
Diagnostic Nasal Endoscopy (1997)

New York, N.Y., and Dallas, Texas From the Department of Plastic Surgery at the University of Texas Southwestern Medical Center, Dallas, Texas, and from private practice in New York. Department of Plastic Surgery; University of Texas, Southwestern Medical Center; 5323 Harry Hines Boulevard; Dallas, Texas 75235-9132 Received for publication October 8, 1996.
Curdlan sulphate in human severe/cerebral Plasmodium falciparum malaria (2005)

Preclinical studies have shown that curdlan sulphate (CRDS), a sulphated 1-->3-beta-D glucan, inhibits Plasmodium falciparum in vitro and down-modulates the immune response. A direct, non-specific effect on cytoadherence and rosetting may be predicted, as has been described with other sulphated polysaccharides, e.g. heparin. The anticoagulant effect of CRDS is 10-fold lower than heparin. Curdlan sulphate has, therefore, emerged as a candidate for adjunct medication in the treatment of severe/cerebral malaria. Two clinical studies were conducted using CRDS as adjunct medication to conventional therapy (artesunate) in patients with severe and severe/cerebral malaria. Both studies were double-blind and placebo-controlled to evaluate the efficacy and safety of the combination. Curdlan sulphate appeared to reduce the severity of the disease process, e.g. fever clearance time was shortened. Due to the small number of patients, there was no difference in mortality. The two treatment arms in both studies showed similar results for all laboratory parameters. The only adverse event recorded during CRDS treatment was an increase in activated partial thromboplastin time. This can be monitored easily. It seems that the patients who may benefit most are severe/cerebral cases with no organ damage on admission.
Twenty-four hour ambulatory blood pressure monitoring (2005)

Drug Prescribing for Patients with Chronic Kidney Disease in General Practice: a Cross-Sectional Study
Effects of nutritional factors and soil addition on growth, longevity and fecundity of the tadpole shrimp Triops newberryi (Notostraca: Triopsidae), a potential biological control agent of immature mosquitoes. (2001)

The notostracan tadpole shrimp (TPS) Triops newberryi Packard has potential to be used as a biocontrol agent of immature mosquitoes. Eggs, nymphal or adult shrimps are considered to be the stages for field introduction. To yield good growth of the shrimp and high production of shrimp eggs under artificial conditions, nutritional requirements of TPS for growth, survival and fecundity need to be elucidated. In the laboratory, we evaluated various nutritional and edaphic regimens, such as soil alone, mosquito larvae or rabbit pellets alone and various combinations of these three components for culturing. These factors influenced the growth, longevity and egg production profoundly. It was shown that the simulated natural conditions, i.e. full combination of all three factors, yielded the largest TPS with longest survival and highest egg production, followed by the combinations of any two components. Any single component, soil, mosquito larvae, or rabbit pellets, did not result in good growth, survival and egg production. By formulating optimal rearing substrates, this species of TPS will yield large numbers of all stages for experimentation and field introductions. Under optimal conditions, they mature in 7-8 days and survive for about one month. Each TPS is capable of producing up to 1,000 eggs during its lifetime. These studies developed nutritional regimens for TPS mass culturing procedures, where the eggs, nymphal and adult TPS can be mass cultured for field introduction and stocking in mosquito developmental sites.
A Homogeneous HLA-B*27 Genotyping Assay Using Dried Reagent Mixtures (2009)

The presence of HLA-B*27 allele with patients suspected with ankylosing spondylitis can be used in the diagnostic process. We have developed an assay for typing for the HLA-B*27 in whole blood dried on sample collection cards using pre-dried reagent wells and homogeneous time-resolved fluorescence based PCR approach. Essentially only the sample needs to be added to the dry ready-to-use reaction well in order to start the homogenous amplification assay. The method was validated with 229 samples also typed with an existing DELFIA-based method and results of both assays were 100% concordant. The dried reagents were shown to be stable at least up to eight weeks at room temperature without any decline in their performance.
Definition of Throw-Away Detectors (TADs) and VLF antenna for the AMPS laboratory (1975)

A Throw Away Detector (TAD)/subsatellite to be used as an experiment platform for the test flights to map the EMI from the shuttle and during the AMPS science flights is defined. A range of instrument platforms of varying capabilities is examined with emphasis on the EMI test vehicle. The operational support requirements of TAD/subsatellites are determined. The throw away detector is envisioned as a simple instrument package for supporting specific experiments.
Sampling problems and the determination of mercury in surface water, seawater, and air. [Neutrons] (1976)

Analysis of surface water for mercury comprises the determination of both ionic and organically bound mercury in solution and that of the total mercury content of the suspended matter. Eventually, metallic mercury has to be determined too. Requirements for the sampling procedure are given. A method for the routine determination of mercury in surface water and seawater was developed and applied to Dutch surface waters. The total sample volume is 2500 ml. About 500 ml is used for the determination of the content of suspended matter and the total amount of mercury in the water. The sample is filtered through a bed of previously purified active charcoal at a low flow-rate. The main portion ca. 2000 ml) passes a flow-through centrifuge to separate the solid fraction. One liter is used to separate ''inorganic'' mercury by reduction, volatilization in an airstream and adsorption on active charcoal. The other liter is led through a column of active charcoal to collect all mercury. The procedures were checked with /sup 197/Hg radiotracer both as an ion and incorporated in organic compounds. The mercury is determined by thermal neutron activation, followed by volatilization in a tube furnace and adsorption on a fresh carbon bed. The more » limit of determination is approximately equal to 1 ng 1/sup -1/. The rate of desorption from and adsorption on suspended material has been measured as a function of a pH of the solution for Hg/sup +2/ and various other ions. It can be concluded that only the procedure mentioned above does not disturb the equilibrium. The separation of mercury from air is obtained by suction of 1 m/sup 3/ through a 0.22 ..mu..m filter and a charcoal bed. The determination is then performed as in the case of the water samples. « less
Enhancement by Thyroid Hormone of Free and Bound RNA Polymerase IB Activities in Rat Liver Nucleoli1 (1980)

After having defined reliable assay conditions for free and template-bound RNA polymerase I activities, we examined in detail the effect of thyroid hormone in vivo on nucleolar RNA polymerase I in rat liver. The enzyme activity decreased markedly in the hypothyroid state produced by either thyroidectomy, hypophysectomy or by administration of propylthiouracil (PTU). One large dose (25 microgram/100 g body weight) of T3 given intraperitoneally caused a rapid recovery of the enzyme activity within 24 h either in the presence or absence of the pituitary. The enzyme activity of both free and chromatin-bound enzyme changed in parallel throughout. A similar recovery was noted after daily subcutaneous injections of a physiological dose (1 microgram/100 g body weight) of T3 for about 3 weeks. Analyses of subfractions of the enzyme indicated that only IB-type enzyme (the enzyme fraction containing the whole set of subunits) changed in response to thyroid hormone action, also irrespective of the presence or absence of the pituitary. The possibility that thyroid hormone is a major physiological regulator of the synthesis of RNA polymerase I in rat liver is discussed.
Synthesis and Characterization of the Germathioacid Chloride Coordinated by an N-Heterocyclic Carbene § (2018)

Carboxylic acid chlorides are useful substrates in organic chemistry. Many germanium analogues of carboxylic acid chloride have been synthesized so far. Nevertheless, all of the reported germathioacid chlorides use bidentate nitrogen ligands and contain germanium-nitrogen bonds. Our group synthesized germathioacid chloride, Ge(S)Cl{C6H3-2,6-Tip2}(Im-i-Pr2Me2), using N-heterocyclic carbene (Im-i-Pr2Me2). As a result of density functional theory (DFT) calculation, it was found that electrons are localized on sulfur, and the germanium-sulfur bond is a single bond with a slight double bond property.
Don't cheat the order sheet (2008)

President of the Institute for Safe Medication Practices The reports described in Medication Errors were received through the USP-ISMP Medication Errors Reporting Program. Report errors, close calls, or hazardous conditions to the Institute for Safe Medication Practices (ISMP) at http://www.ismp.org or the United States Pharmacopeia (USP) at http://www.usp.org. You can also call ISMP at 1-800-FAIL SAFE or send an e-mail message to [email protected]. Michael R. Cohen is a member of the Nursing2008 editorial advisory board.
Low-Frequency Eddy Current Imaging Using MR Sensor Detecting Tangential Magnetic Field Components for Nondestructive Evaluation (2006)

An eddy-current distribution imaging system using a wide-area magnetic field exposure has been developed. This system can be employed to detect deep metal cracks using a magnetic resistive (MR) sensor. The measuring system consists of the exposure coil, MR sensors, measuring circuits, lock-in amplifier, xy stage, and a personal computer. To detect the eddy current distribution, the imaging system uses a pair of MR sensors that detect the x and y magnetic field components parallel to the metal surface. The system operates at a low-frequency range in order to obtain depth of penetration. An artificial defect consisting of a multilayer Al substrate sample with a bottom half slit was measured to test the system. The change in the eddy current distribution image due to the presence of the flaw was obtained. In particular, it was determined that the detection of the slit depth was improved by this lower exposure frequency
Cancer preventive agents 10. Prenylated dehydrozingerone analogs as potent chemopreventive agents (2020)

Dehydrozingerone analogs and related compounds were screened as potential antitumor promoters by using the in vitro short-term 12-O-tetradecanphorbol-13-acetate (TPA)-induced Epstein-Barr virus early antigen (EBV-EA) activation assay. Among 40 synthesized compounds, the prenylated analogs 16 and 34–36 showed the most significant and promising activity (100% inhibition of activation at 1×10 3 mol ratio/TPA, and 82–80%, 37–35%, 13–11% inhibition at 5×102, 1×102, 1×10 mol ratio/TPA, respectively) in this screening. Their activity profiles were comparable to that of the reference standard curcumin. While a prenyl moiety conferred potent chemopreventive activity, an extended prenyl unit such as a farnesyl moiety did not improve activity. Because in vitro inhibitory effects in this assay generally correlate well with in vivo inhibitory effects on tumor promotion, our results strongly suggested that prenylated 16 and 34–36 are likely to be promising antitumor promoters.
Energy Management of Refrigeration Systems with Thermal Energy Storage Based on Non-Linear Model Predictive Control (2022)

This work addresses the energy management of a combined system consisting of a refrigeration cycle and a thermal energy storage tank based on phase change materials. The storage tank is used as a cold-energy buffer, thus decoupling cooling demand and production, which leads to cost reduction and satisfaction of peak demand that would be infeasible for the original cycle. A layered scheduling and control strategy is proposed, where a non-linear predictive scheduler computes the references of the main powers involved (storage tank charging/discharging powers and direct cooling production), while a low-level controller ensures that the requested powers are actually achieved. A simplified model retaining the dominant dynamics is proposed as the prediction model for the scheduler. Economic, efficiency, and feasibility criteria are considered, seeking operating cost reduction while ensuring demand satisfaction. The performance of the proposed strategy for the system with energy storage is compared in simulation with that of a cycle without energy storage, where the former is shown to satisfy challenging demands while reducing the operating cost by up to 28%. The proposed approach also shows suitable robustness when significant uncertainty in the prediction model is considered.
Recombinant Human Interleukin-6 Enhances the Immunoglobulin Secretion of a Rabbit–Rabbit Hybridoma (2001)

The generation of stable rabbit-rabbit hybridomas is now possible by the recent development of a rabbit fusion partner. The ability to generate rabbit monoclonal antibodies (MAbs) can be advantageous because these rabbit immunoglobulins tend to exhibit higher affinity than murine MAbs. Furthermore, it has been observed that, in general, rabbits will elicit an immune response to antigens of limited immunogenicity in mice. Unfortunately, these rabbit-rabbit hybridomas secrete only 200 ng/mL to 5 microg/mL of immunoglobulin, which may limit larger scale production of rabbit antibodies. This study sought to determine if interleukin 6 (IL-6), which has been reported to have proliferative and secretory stimulating effects on some murine hybridomas, had any effect on a rabbit cell line that secretes a monoclonal IgG specific for estradiol. The results demonstrated that recombinant human IL-6 had a dose-dependent enhancing effect on the IgG secretion of the rabbit-rabbit hybridoma. The enhancing effect was consistent when the cells were continuously passed in the presence of IL-6. However, IL-6 did not affect the growth of the hybridoma. In contrast, no discernible effect was accomplished with recombinant mouse IL-6. Furthermore, no basal IL-6 activity was detected in the rabbit hybridoma extracellular medium. The IL-6 enhancement effect observed in this study may help to increase the immunoglobulin yield of rabbit hybridomas and to assist in the understanding of the mechanism(s) behind the lowered secretion level.