gebhart/patrepeval huggingface dataset:
THE IMPACT OF THE PROBIOTIC BACTERIA ON THE CONTAMINATED MICROBIAL OF THE FEMALE GENITAL TRACT AND ITS EFFECT ON THE IVF OUTCOME (2018)

The microbial contamination of the female genital tract has effect on the ivf outcome and negatively effect on fertility, fertilization and implantation rate. Lactobacillus sp. is the dominant organism of the vaginal flora that have an important role in the inhibition of pathogen. 48 patients were selected for this study aged between 20-40 years, During embryo transfer, 3 samples were collected from each patient from vagina, end cervical canal and the tip of the catheter. The samples were assayed microbiology. The microbial culture contained natural flora and pathogen organism .The isolated pathogens were identified as Klebsilla pneumonia, Escherichia coli, Candida albicans, C. tropicalis, C. famata, C. parapsilosis, C. catenulate according to Bergeyˊs manual and confirmed by VITEK System. Candida sp found to be the most frequent infemale genital tract. The probiotic (Lactobacillus. acidophilus) and its metabolites (bacteriocin) were inhibited growth of isolated pathogenic microbial in vitro.The result showed that L. acidophilus and their metabolite bacteriocin have antagonistic activity against pathogenic microbes. Recommendation: Oral or transvaginal administration of Lactobacillus or bacteriocin antiseptics; disinfected; maintain a health vagina and prevent the infection of the reproductive tract.
Conceptual Design of Laser-Diode-Pumped Water-Cooled Nd:Glass Slab Laser Driver for Inertial Fusion Energy. (2000)

We have proposed and designed a laser-diode-pumped laser driver for inertial fusion energy (IFE) which consists of water-cooled zig-zag path Nd: glass (HAP-4) slab amplifiers. A driver module was designed under the several operational constraints and has 10 kJ total output energy at 351 nm and operates at 12 Hz with 9-12% overall efficiency. The laser driver producing 4 MJ blue output for IFE will consist of 400 modules
Implication des protéines anti-apoptotiques de la famille Bcl-2 dans la dépendance aux signaux de survie des cancers du sein des sous-types HER2 et Lumina (2010)

Le cancer du sein est une maladie heterogene notamment dans sa diversite et sa dependance aux voies de signalisation oncogeniques (par exemple, voie HER2). Ces dependances traduisent l’activation par les oncogenes de signaux antagonistes, de mort et de survie, de proliferation et d'arret cellulaire. Les proteines de la famille Bcl-2 constituent un point d'integration majeur des signaux de survie et de mort des cellules cancereuses. La fonction des proteines anti-apoptotique repose sur leur capacite a interagir physiquement avec leurs contreparties apoptotiques. Cette interaction est manipulable pharmacologiquement. Nous avons etudie si la survie des cellules tumorales mammaires dependait de l'activite anti-apoptotique de certains homologues de Bcl-2 et si leur inhibition etait susceptible d'avoir un effet therapeutique. Par une premiere approche in vitro, nous avons mis en evidence que la survie de cellules surexprimant HER2 dependait de Mcl-1 et qu'elle etait liee a l'expression constitutive de la proteine pro-apoptotique Bim, elle-meme liee au facteur de transcription c-Myc, situe en aval de HER2. Cette etude montre que l'equilibre Bim/Mcl-1 joue un role cle dans la regulation de la survie des cellules de cancer du sein surexprimant HER2. Dans une seconde approche, ex-vivo, nous avons expose des prelevements de tumeurs du sein de patientes a l’ABT-737, un inhibiteur de Bcl-2 et Bcl-xL. Nos resultats montrent qu'il induit une apoptose massive dans certaines tumeurs mammaires et a peu d'effet dans d'autres cas. Nous concluons que la voie HER2 peut induire un signal de mort qui rend necessaire des signaux compensatoires de survie reposant sur l'activite des homologues de Bcl-2, instaurant un etat de dependance aigue a ces signaux. Les approches fonctionnelles realises ex-vivo confirment cette notion tout en montrant qu'elle ne s’applique pas systematiquement. Elles fournissent l'outil methodologique qui permet de detecter de telles dependances, et d'etudier les voies qui les installent ou les inhibent.
38. Functional characterisation of a lymphocyte-suppressing activity in gonadal fluid (2003)

Reproduction, Fertility and Development is an international journal publishing original research , review and comment in the fields of reproduction and developmental biology in humans, domestic animals and wildlife
Viscosity Behavior of Alkaline, Surfactant, Polyacrylamide Solutions Used for Enhanced Oil Recovery (1991)

Abstract An experimental study was conducted to examine the effects of various alkalis, surfactants and brines on the viscosity of dilute aqueous solutions of Alcoflood 1175L, a partially hydrolyzed polyacrylamide polymer, over a wide range of parameters. In general, the viscosity-shear rate relationship exhibited a Newtonian behavior at low shear rates and a power-law behavior at high shear rates. Adding a non-ionic species (Triton X-100) had an insignificant effect on the viscosity-shear rate relationship. However, adding an ionic species, (sodium chloride, calcium chloride, or an anionic surfactant) reduced the hydrodynamic size of the polymer molecule (physical change), changing the viscosity-shear rate relationship. The viscosity-shear rate relationship was found to be a strong function of cation type only at salt concentrations less than 4 wt%. For a given polymer concentration, the power-law constants were found to be exponentially related. The effect of alkalis on the viscosity of polymer solutions was complex as they affected the polymer chain both physically (charge shielding) and chemically (hydrolysis). For alkali/polymer solutions, the viscosity was found to be a function of alkali type, concentration and time after initial mixing. The effect of these parameters on the viscosity of alkali/polymer solutions diminished by adding NaCl. The addition of anionic surfactants at low concentrations slightly decreased alkali/polymer solutions viscosity. However, a significant viscosity enhancement for alkali/polymer solutions was observed at higher surfactant concentrations and over a narrow range of alkali concentrations.
Adverse events with orbital atherectomy: an analytic review of the MAUDE database (2020)

Introduction Coronary artery calcification (CAC) poses a challenge for successful percutaneous coronary intervention. CAC is associated with worse periprocedural and long-term clinical outcomes because of difficult device delivery and inadequate stent expansion. Atherectomy can effectively ablate and modify calcified plaques, optimising procedural outcomes. The Diamondback 360® Coronary Orbital Atherectomy System (Cardiovascular Systems, Inc., St. Paul, MN, USA) is indicated for lesion preparation of de novo severely calcified coronary lesions before stent implantation. Orbital atherectomy (OA) employs an eccentrically mounted 1.25 mm diamond-coated crown that utilises centrifugal force to orbit at either 80,000 or 120,000 rpm. OA has a unique bidirectional mechanism ...
Quality of Life in hematology: European Hematology Association theme of the year ... and years to come (2012)

For many years, through its dedicated scientific working group and sessions at its Annual Congress, the European Hematology Association (EHA) has underscored the commitment of hematologists to address the issue of Quality of Life of patients affected by hematologic diseases. Understandably, when the
Design of Band-Notched Ultrawideband Square Aperture Antenna With a Hat-Shaped Back-Patch (2008)

A new square aperture antenna fed by a coplanar waveguide (CPW) is proposed for ultrawideband (UWB) applications. A corner-notched rectangular patch was printed on the backside of the substrate for enhancing the impedance bandwidth. Impedance matching for different ranges within the UWB can be easily obtained by adjusting the width and height of the back-patch, the distance from the back-patch to the lower edge of the aperture, and the size of the two notched corners in the back-patch. A rejected frequency band within the UWB was produced by embedding a pair of U-shaped slotlines in the back-patch. Measured and simulated results are presented along with simple design rules.
Scaling replicated state machines with compartmentalization (2021)

State machine replication protocols, like MultiPaxos and Raft, are a critical component of many distributed systems and databases. However, these protocols offer relatively low throughput due to several bottlenecked components. Numerous existing protocols fix different bottlenecks in isolation but fall short of a complete solution. When you fix one bottleneck, another arises. In this paper, we introduce compartmentalization, the first comprehensive technique to eliminate state machine replication bottlenecks. Compartmentalization involves decoupling individual bottlenecks into distinct components and scaling these components independently. Compartmentalization has two key strengths. First, compartmentalization leads to strong performance. In this paper, we demonstrate how to compartmentalize MultiPaxos to increase its throughput by 6× on a write-only workload and 16× on a mixed read-write workload. Unlike other approaches, we achieve this performance without the need for specialized hardware. Second, compartmentalization is a technique, not a protocol. Industry practitioners can apply compartmentalization to their protocols incrementally without having to adopt a completely new protocol.
A comparison of neural network and fuzzy clustering techniques in segmenting magnetic resonance images of the brain (1992)

Magnetic resonance (MR) brain section images are segmented and then synthetically colored to give visual representations of the original data with three approaches: the literal and approximate fuzzy c-means unsupervised clustering algorithms, and a supervised computational neural network. Initial clinical results are presented on normal volunteers and selected patients with brain tumors surrounded by edema. Supervised and unsupervised segmentation techniques provide broadly similar results. Unsupervised fuzzy algorithms were visually observed to show better segmentation when compared with raw image data for volunteer studies. For a more complex segmentation problem with tumor/edema or cerebrospinal fluid boundary, where the tissues have similar MR relaxation behavior, inconsistency in rating among experts was observed, with fuzz-c-means approaches being slightly preferred over feedforward cascade correlation results. Various facets of both approaches, such as supervised versus unsupervised learning, time complexity, and utility for the diagnostic process, are compared.
Multi-Channel Microstrip Transceiver Arrays Using Harmonics for High Field MR Imaging in Humans (2011)

Radio-frequency (RF) transceiver array design using primary and higher order harmonics for in vivo parallel magnetic resonance imaging imaging (MRI) and spectroscopic imaging is proposed. The improved electromagnetic decoupling performance, unique magnetic field distributions and high-frequency operation capabilities of higher-order harmonics of resonators would benefit transceiver arrays for parallel MRI, especially for ultrahigh field parallel MRI. To demonstrate this technique, microstrip transceiver arrays using first and second harmonic resonators were developed for human head parallel imaging at 7T. Phantom and human head images were acquired and evaluated using the GRAPPA reconstruction algorithm. The higher-order harmonic transceiver array design technique was also assessed numerically using FDTD simulation. Compared with regular primary-resonance transceiver designs, the proposed higher-order harmonic technique provided an improved g-factor and increased decoupling among resonant elements without using dedicated decoupling circuits, which would potentially lead to a better parallel imaging performance and ultimately faster and higher quality imaging. The proposed technique is particularly suitable for densely spaced transceiver array design where the increased mutual inductance among the elements becomes problematic. In addition, it also provides a simple approach to readily upgrade the channels of a conventional primary resonator microstrip array to a larger number for faster imaging.
Supplementary Figure from Combined Perioperative Lapatinib and Trastuzumab in Early HER2-Positive Breast Cancer Identifies Early Responders: Randomized UK EPHOS-B Trial Long-Term Results (2023)

Supplementary Figure from Combined Perioperative Lapatinib and Trastuzumab in Early HER2-Positive Breast Cancer Identifies Early Responders: Randomized UK EPHOS-B Trial Long-Term Results
The Adenovirus Ela Gene Induces Differentiation of F9 Teratocarcinoma Cells (1987)

Undifferentiated F9 cells transfected with plasmids encoding adenovirus E1a gene products underwent radical morphological changes. They ceased to express the SSEA-1 stem cell marker antigen and started to express a number of the characteristics of the differentiated state that is induced in F9 cells by treatment with retinoic acid. In particular, they expressed keratin intermediate filaments and acquired the ability to synthesise simian virus 40 tumor antigens after virus infection. The transfected cells expressed the E1a proteins, and this expression was necessary to induce the phenotypic changes, since a coisogenic plasmid encoding only a truncated 70-amino-acid E1a polypeptide and the transfection procedure itself did not detectably after the morphology or marker expression of the F9 stem cells. The phenotypic change was induced by both 13S and 12S cDNA plasmids. We discuss these results in the context of known E1a functions and with reference to the other oncogenes and external factors that can cause F9 cell differentiation.
Characterization of Two Different Five-Coordinate Soluble Guanylate Cyclase Ferrous–Nitrosyl Complexes (2008)

Soluble guanylate cyclase (sGC), a hemoprotein, is the primary nitric oxide (NO) receptor in higher eukaryotes. The binding of NO to sGC leads to the formation of a five-coordinate ferrous-nitrosyl complex and a several hundred-fold increase in cGMP synthesis. NO activation of sGC is influenced by GTP and the allosteric activators YC-1 and BAY 41-2272. Electron paramagnetic resonance (EPR) spectroscopy shows that the spectrum of the sGC ferrous-nitrosyl complex shifts in the presence of YC-1, BAY 41-2272, or GTP in the presence of excess NO relative to the heme. These molecules shift the EPR signal from one characterized by g 1 = 2.083, g 2 = 2.036, and g 3 = 2.012 to a signal characterized by g 1 = 2.106, g 2 = 2.029, and g 3 = 2.010. The truncated heme domain constructs beta1(1-194) and beta2(1-217) were compared to the full-length enzyme. The EPR spectrum of the beta2(1-217)-NO complex is characterized by g 1 = 2.106, g 2 = 2.025, and g 3 = 2.010, indicating the protein is a good model for the sGC-NO complex in the presence of the activators, while the spectrum of the beta1(1-194)-NO complex resembles the EPR spectrum of sGC in the absence of the activators. Low-temperature resonance Raman spectra of the beta1(1-194)-NO and beta2(1-217)-NO complexes show that the Fe-NO stretching vibration of the beta2(1-217)-NO complex (535 cm (-1)) is significantly different from that of the beta1(1-194)-NO complex (527 cm (-1)). This shows that sGC can adopt different five-coordinate ferrous nitrosyl conformations and suggests that the Fe-NO conformation characterized by this unique EPR signal and Fe-NO stretching vibration represents a highly active sGC state.
The kinetics of package life. III. The isotherm (1946)

Abstract Published equations for the sorption isotherms of hygroscopic materials cannot be used in solving the Package Life equation, but it has been found empirically that Pearson's typo XII Frequency curve can be fitted to the isotherms of many non‐crystalline commodities. Approximate solutions of the equation for the shelf‐life of water‐sensitive packages are derived. Separate equations are derived for absorption and desorption: the agreement of each with results observed in exposure trials is demonstrated.
Charge trapping and device performance degradation in MOCVD hafnium-based gate dielectric stack structures (2004)

Electron trapping data obtained with the pulsed I/sub d/-V/sub g/ measurement suggests that the trapping effectively occurs in the bulk of the high-k film rather than only at the interface of the high-k dielectric and interfacial oxide. This leads to less trapping in physically thinner high-k gate stacks. Carrier mobility of thinner hybrid stacks corrected for the inversion charge loss due to electron trapping is found to be approaching the universal high field electron mobility.
Measurement of diffusivity and solubility of olefins in polypropylene by gas chromatography (2000)

The classical gas chromatographic technique is applied to measure the solubility and diffusivity of ethylene and propylene in polypropylene. The polymer particles were used as supplied by the producers to pack the chromatographic columns. This allows a direct measurement of the interested properties in a particle with the same morphology obtained at the reactor outlet. Moreover, the apparatus was adapted to carry out measurements at pressures and temperatures close to those typical of the reaction conditions. The measured values of solubility and diffusivity compare favorably with those predicted by literature relationships for semicrystalline polymeric matrices. Moreover, the estimated diffusivities indicate the diffusion in the polymer microparticles as the rate determining step and a diffusive characteristic length comparable with the particle diameter, i.e., larger than expected in the frame of a multigrain particle schematization. © 2000 John Wiley & Sons, Inc. J Appl Polym Sci 78: 464–473, 2000
Position Sensorless Control Based on Coordinate Transformation for Brushless DC Motor Drives (2010)

This paper presents a novel method for sensorless brushless dc (BLDC) motor drives. Based on the characteristics of the back electromotive force (EMF), the rotor position signals would be constructed. It is intended to construct these signals, which make the phase difference between the constructed signals and the back EMFs controllable. Then, the rotor-position error can be compensated by controlling the phase-difference angle in real time. In this paper, the rotor-position-detection error is analyzed. Using the TMS320F2812 chip as a control core, some experiments have been carried out on the prototype, which is the surface-mounted permanent magnet BLDC motor, and the experimental results verify the analysis and demonstrate advantages of the proposed sensorless-control method.
A possible melanoma discrimination index based on hyperspectral data: a pilot study (2011)

An objective melanoma discrimination index at a molecular pigmentary level, derived from HSD, has been proposed, and its performance evaluated. This index was highly successful in discriminating MM from non-melanoma, although the statistical population was small.
Hybrid germanium/silica optical fibers for endoscopic delivery of erbium:YAG laser radiation (2004)

Hybrid germanium/silica fibers represent a robust, flexible, and biocompatible method of delivering Er:YAG laser radiation during contact soft tissue ablation. However, significant improvement in the hybrid fibers will be necessary before they can be used for efficient Er:YAG laser lithotripsy.
Next Generation Network Infrastructure Enabling Telemonitoring Services (2006)

In the next few decades one of the main problems to deal with in Western Europe is the aging of the population. The healthcare sector will face rising costs and increasing workload. Telemonitoring and networks of professional and voluntary health workers are promising solution directions to deal with both the cost and workload challenges. In this paper a study on telemonitoring services with a network of health workers using next generation network infrastructure is presented. Next generation network infrastructure technologies like Session Initiation Protocol and IP Multimedia Subsystem offer service enablers that help realise a telemonitoring solution that can call in a dynamic network of health workers. Content repurposing is an important component in this solution enabling the distribution of multimedia content to the large variety of devices. wNext Generation Network Infrastructure Enabling Telemonitoring Services
Operational modes of a 2.0 MWth chloride molten-salt pilot-scale system (2020)

The limit of traditional solar-salt thermal stability is around 600 °C with ambient air as the cover gas. Nitrate molten salt concentrating solar power (CSP) systems are currently deployed globally and are considered to be state-of the art heat transfer fluids (HTFs) for present day high-temperature operation. However, decomposition challenges occur with these salts for operation beyond 600 C. Although slightly higher limits may be possible with solar salt, to fully realize SunShot efficiency goals of $15/kWhth HTFs and an LCOE of 6¢/kWh, molten-salt technologies working at higher temperatures (e.g., 650 °C to 750 °C) will require an alternative salt chemistry composition, such as chlorides.In this investigation a 2.0MWth Pilot-scale CSP plant design is developed to assess thermodynamic performance potential for operation up to 720 C. Here, an Engineering Equation Solver (EES) model is developed with respect to 14 state-points from the base of a solar tower at the Sandia National Laboratories, National Solar Thermal Test Facility (NSTTF), to solar receiver mounted 120 ft. above the ground. The system design considers a ternary chloride ternary chloride (20%NaCl/40%MgCl/40%KCl by mol%) salt as the HTF, with 6 hrs. of storage and a 1 MWth primary salt to sCO2 heat exchanger. Preliminary system modelling results indicate a minimum non-dimensional Cv of 60 required for both cold and hot-side throttle recirculation valves for the operational pump operating between speeds of 1800 and 2400 RPM. Further receiver comparison study results suggest that the ternary salt requires an average 15.2% higher receiver flux with a slightly lower calculated receiver efficiency when compared to a binary carnelite salt to achieve a 2.0 MWth desired input power design.
10.7-Gb/s Discrete Multitone Transmission Over 25-m Bend-Insensitive Multicore Polymer Optical Fiber (2010)

We report on 10.7-Gb/s transmission over 25-m multicore polymer optical fiber (MC-POF) which allows a robust transmission and ease of installation including tight bends. The discrete multitone modulation technique is applied to the intensity-modulated direct-detection optical channel in order to achieve high spectral efficiency. The use of bend-insensitive MC-POF reduces significantly the admissible bending radius to 2.5 mm without any signal distortion resulting in a very robust installation. The POF-optimized receiver comprises a silicon pin photodiode with an active diameter of 400 and a transimpedance amplifier.