gebhart/patrepeval huggingface dataset:
Measurements of Non-Ionizing Radiation Levels in an Urban Environment (2006)

In this paper, we resume the results of electromagnetic radiation measurements performed in the urban environment of the city of Santander, in Spain from radioelectric systems that operate in the area of the city of Santander, in the North of Spain. They include mobile telephony, radio and television broadcasting, police and private communications in the VHF and UHF bands. Four different measuring equipments were used, two of them wideband with isotropic probes and two, narrowband with dipole antennas. Special attention was put in places such as schools and geriatric residences. Furthermore, a wide survey through the urban area of the city was carried out, collecting more than 20,000 samples at street level which were statistically analyzed
A prospective multicentre study testing the diagnostic accuracy of an automated cough sound centred analytic system for the identification of common respiratory disorders in children (2019)

Australian and New Zealand Clinical Trial Registry (retrospective) - ACTRN12618001521213 : 11.09.2018.
Robust finite-time attitude tracking control for nonlinear quadrotor with uncertainties and delays (2017)

In this paper, the robust finite-time attitude tracking problem for quadrotor system is investigated under the influences of coupled and nonlinear dynamics, parametric and unmodeled uncertainties, external disturbances and time-varying input and feedback delays. The robust finite-time attitude tracking controller is designed with a novel nonsingular terminal sliding mode control strategy. Finite-time convergence is proven and explicitly given based on Lyapunov approaches. Simulations are presented to illustrate the effectiveness of the proposed controller. Experimental results are given to confirm the attitude tracking performance of the control strategy.
Laparoscopic Repair of a Man with Massive Bilateral Femoral Hernias (2009)

In this review, we describe a laparoscopic totally extraperitoneal (TEP) repair of a man with massive bilateral femoral hernias that had been chronically incarcerated, which has not previously been described in the literature. Our purpose is to not only to describe our laparoscopic technique and postoperative management, but also to comprehensively review the literature regarding the principles of laparoscopic hernia repair and specifically laparoscopic femoral hernia repair. TEP repair is a safe approach to the surgical management of femoral hernias, including those that are incarcerated, and furthermore offers the advantage of repairing other concomitant hernias, which may be more prevalent than expected.
On the performance of an optimized NLMS algorithm (2015)

The recently proposed joint-optimized normalized least-mean-square (JO-NLMS) algorithm was developed in the context of a state variable model. Moreover, following the minimization of the system misalignment and using an iterative procedure for adjusting the system model parameter, this algorithm is able to achieve a proper compromise between the performance criteria (i.e., fast convergence/tracking and low misadjustment). In this paper, we present a performance analysis of the JO-NLMS algorithm, outlining some relations between its main parameters and indicating its good behavior.
A vertically discretised canopy description for ORCHIDEE (SVN r2290) and the modifications to the energy, water and carbon fluxes (2015)

Abstract. Since 70 % of global forests are managed and forests impact the global carbon cycle and the energy exchange with the overlying atmosphere, forest management has the potential to mitigate climate change. Yet, none of the land-surface models used in Earth system models, and therefore none of today's predictions of future climate, accounts for the interactions between climate and forest management. We addressed this gap in modelling capability by developing and parametrising a version of the ORCHIDEE land-surface model to simulate the biogeochemical and biophysical effects of forest management. The most significant changes between the new branch called ORCHIDEE-CAN (SVN r2290) and the trunk version of ORCHIDEE (SVN r2243) are the allometric-based allocation of carbon to leaf, root, wood, fruit and reserve pools; the transmittance, absorbance and reflectance of radiation within the canopy; and the vertical discretisation of the energy budget calculations. In addition, conceptual changes were introduced towards a better process representation for the interaction of radiation with snow, the hydraulic architecture of plants, the representation of forest management and a numerical solution for the photosynthesis formalism of Farquhar, von Caemmerer and Berry. For consistency reasons, these changes were extensively linked throughout the code. Parametrisation was revisited after introducing 12 new parameter sets that represent specific tree species or genera rather than a group of often distantly related or even unrelated species, as is the case in widely used plant functional types. Performance of the new model was compared against the trunk and validated against independent spatially explicit data for basal area, tree height, canopy structure, gross primary production (GPP), albedo and evapotranspiration over Europe. For all tested variables, ORCHIDEE-CAN outperformed the trunk regarding its ability to reproduce large-scale spatial patterns as well as their inter-annual variability over Europe. Depending on the data stream, ORCHIDEE-CAN had a 67 to 92 % chance to reproduce the spatial and temporal variability of the validation data.
Counterselectable Markers: Untapped Tools for Bacterial Genetics and Pathogenesis (1998)

International audience
Lidar Mapping Optimization Based on Lightweight Semantic Segmentation (2019)

Lidar Simultaneous Localization and Mapping (LiDAR-SLAM) algorithm with semantic information is an open research question and it is such a time consuming task. The related work that focus on real-time LiDAR-SLAM has poor accuracy. To solve these problems, a lightweight semantic segmentation network to assist in localization and mapping is proposed in this paper. The method uses the lidar point clouds generated by the simulator and annotated manually in real world as the original input. Then, the semantic cloud is segmented by the semantic segmentation network to obtain the semantic information. Finally, the semantic information obtained by the segmentation is used to assist the localization and mapping.
Assessment of Therapeutic Response in Hepatocellular Carcinoma Treated With Percutaneous Radio Frequency Ablation (2002)

The results of contrast-enhanced power Doppler ultrasonography closely correlated with those of immediate follow-up computed tomography for detecting residual tumors in hepatocellular carcinomas treated with radio frequency ablation. Both techniques, however, showed a limitation in detecting small or microscopic residual tumors and in predicting local regrowth in the treated lesions.
Transport of intensity equation: a tutorial (2020)

When it comes to “phase measurement” or “quantitative phase imaging”, many people will automatically connect them with “laser” and “interferometry”. Indeed, conventional quantitative phase imaging and phase measurement techniques generally rely on the superposition of two beams with a high degree of coherence: complex interferometric configurations, stringent requirements on the environmental stabilities, and associated laser speckle noise severely limit their applications in optical imaging and microscopy. On a different note, as one of the most well-known phase retrieval approaches, the transport of intensity equation (TIE) provides a new non-interferometric way to access quantitative phase information through intensity only measurement. Despite the insufficiency for interferometry, TIE is applicable under partially coherent illuminations (like the Köhler’s illumination in a conventional microscope), permitting optimum spatial resolution, higher signal-to-noise ratio, and better image quality. In this tutorial, we give an overview of the basic principle, research fields, and representative applications of TIE, focus particularly on optical imaging, metrology, and microscopy. The purpose of this tutorial is twofold. It should serve as a self-contained introduction to TIE for readers with little or no knowledge of TIE. On the other hand, it attempts to give an overview of recent developments in this field. These results highlight a new era in which strict coherence and interferometry are no longer prerequisites for quantitative phase imaging and diffraction tomography, paving the way toward new generation label-free three-dimensional microscopy, with applications in all branches of biomedicine.
Mass selected clusters on weakly interacting surfaces investigated with UPS (2015)

Mass-selected copper clusters, silver clusters, iron clusters and C60 molecules were deposited on thin rare gas layers (xenon, krypton and argon) to investigate the influence of weakly interacting surfaces on the electronic structure of the clusters. Ultraviolet photoelectron spectroscopy (UPS) was used to image the electronic states of the deposited clusters with a photon energy of 11.62 eV. Gas phase cluster spectra from [Häkkinen et al. (2004); Kostko (2007); Cheshnovsky et al. (1990); Taylor et al. (1992)] are compared with the deposited cluster spectra in order to determine the influences of the surface. UP spectra for the resilient C60 molecule were measured to obtain information about the energetic shift between deposited and gas phase clusters. It was found that there is an additional shift of the spectra by the amount of the electron affinity of the supporting rare gas layer. Further investigations with Cu309 clusters showed the same effect, which justifies the application to the cluster spectra. The comparison between the deposited metal clusters with the same cluster size in the gas phase shows evidence of a quantized signal in the s-p-band region of the clusters. The spectra of Cu147 clusters on various substrates agree with the spectra of free Cu147 clusters. In the outlook the preparation and surface characterizing measurements with LEED and STM of Al2O3/Ni3Al(111), as a functionalized cluster support, is presented.
SAFETY OF LINEZOLID VS VANCOMYCIN IN NOSOCOMIAL PNEUMONIA (2002)

SOCIETY OF CRITICAL CARE MEDICINE 32ND CRITICAL CARE CONGRESS SAN ANTONIO, TEXAS, USA JANUARY 28-FEBRUARY 2, 2003: ORAL/SANDWICH PRESENTATIONS: Poster Presentation: Clinical Science: Sepsis Pneumonia: PDF Only
The Conserved Tetratricopeptide Repeat-Containing C-Terminal Domain of Pseudomonas aeruginosa FimV Is Required for Its Cyclic AMP-Dependent and -Independent Functions (2016)

FimV is important for twitching motility and cAMP-dependent virulence gene expression in P. aeruginosa FimV homologs have been identified in several human pathogens, and their functions are not limited to T4P expression. The C terminus of FimV is remarkably conserved among otherwise very diverse family members, but its role is unknown. We provide here biological evidence for the importance of the C-terminal domain in both cAMP-dependent (through FimL) and -independent functions of FimV. We present X-ray crystal structures of the conserved C-terminal domain and identify a consensus sequence for the C-terminal TPR within the conserved domain. Our data extend our knowledge of FimV's functionally important domains, and the structures and consensus sequences provide a foundation for studies of FimV and its homologs.
Ethylene is involved in strawberry fruit ripening in an organ-specific manner (2013)

The fruit of the strawberry Fragaria×ananassa has traditionally been classified as non-climacteric because its ripening process is not governed by ethylene. However, previous studies have reported the timely endogenous production of minor amounts of ethylene by the fruit as well as the differential expression of genes of the ethylene synthesis, reception, and signalling pathways during fruit development. Mining of the Fragaria vesca genome allowed for the identification of the two main ethylene biosynthetic genes, 1-aminocyclopropane-1-carboxylic acid (ACC) synthase and ACC oxidase. Their expression pattern during fruit ripening was found to be stage and organ (achene or receptacle) specific. Strawberry plants with altered sensitivity to ethylene could be employed to unravel the role of ethylene in the ripening process of the strawberry fruit. To this end, independent lines of transgenic strawberry plants were generated that overexpress the Arabidopsis etr1-1 mutant ethylene receptor, which is a dominant negative allele, causing diminished sensitivity to ethylene. Genes involved in ethylene perception as well as in its related downstream processes, such as flavonoid biosynthesis, pectin metabolism, and volatile biosynthesis, were differently expressed in two transgenic tissues, the achene and the receptacle. The different transcriptional responsiveness of the achene and the receptacle to ethylene was also revealed by the metabolic profiling of the primary metabolites in these two organs. The free amino acid content was higher in the transgenic lines compared with the control in the mature achene, while glucose and fructose, and citric and malic acids were at lower levels. In the receptacle, the most conspicuous change in the transgenic lines was the depletion of the tricarboxylic acid cycle intermediates at the white stage of development, most probably as a consequence of diminished respiration. The results are discussed in the context of the importance of ethylene during strawberry fruit ripening.
Lack of Antiparkinsonian Effects of Systemic Injections of the Specific T-Type Calcium Channel Blocker ML218 in MPTP-Treated Monkeys (2016)

Dopaminergic medications ameliorate many of the motor impairments of Parkinson's disease (PD). However, parkinsonism is often only partially reversed by these drugs, and they can have significant side effects. Therefore, a need remains for novel treatments of parkinsonism. Studies in rodents and preliminary clinical evidence have shown that T-type calcium channel (TTCC) antagonists have antiparkinsonian effects. However, most of the available studies utilized nonselective agents. We now evaluated whether systemic injections of the specific TTCC blocker ML218 have antiparkinsonian effects in MPTP-treated parkinsonian Rhesus monkeys. The animals were treated chronically with MPTP until they reached stable parkinsonism. In pharmacokinetic studies, we found that ML218 reaches a peak CSF concentration 1-2 h after s.c. administration. In electrocardiographic studies, we found no effects of ML218 on cardiac rhythmicity. As expected, systemic injections of the dopamine precursor L-DOPA dose-dependently increased the movements in our parkinsonian animals. We then tested the behavioral effects of systemic injections of ML218 (1, 10, or 30 mg/kg) or its vehicle, but did not detect specific antiparkinsonian effects. ML218 (3 or 10 mg/kg) was also not synergistic with L-DOPA. Using recordings of electrocorticogram signals (in one animal), we found that ML218 increased sleep. We conclude that ML218 does not have antiparkinsonian effects in MPTP-treated parkinsonian monkeys, due at least in part, to the agent's sedative effects.
Positive and Negative Regulation of Muscle Cell Identity by Members of the hedgehog and TGF-β Gene Families (1997)

We have examined whether the development of embryonic muscle fiber type is regulated by competing influences between Hedgehog and TGF-beta signals, as previously shown for development of neuronal cell identity in the neural tube. We found that ectopic expression of Hedgehogs or inhibition of protein kinase A in zebrafish embryos induces slow muscle precursors throughout the somite but muscle pioneer cells only in the middle of the somite. Ectopic expression in the notochord of Dorsalin-1, a member of the TGF-beta superfamily, inhibits the formation of muscle pioneer cells, demonstrating that TGF-beta signals can antagonize the induction of muscle pioneer cells by Hedgehog. We propose that a Hedgehog signal first induces the formation of slow muscle precursor cells, and subsequent Hedgehog and TGF-beta signals exert competing positive and negative influences on the development of muscle pioneer cells.
The architecture of the DIVA processing-in-memory chip (2002)

The DIVA (Data IntensiVe Architecture) system incorporates a collection of Processing-In-Memory (PIM) chips as smart-memory co-processors to a conventional microprocessor. We have recently fabricated prototype DIVA PIMs. These chips represent the first smart-memory devices designed to support virtual addressing and capable of executing multiple threads of control. In this paper, we describe the prototype PIM architecture. We emphasize three unique features of DIVA PIMs, namely, the memory interface to the host processor, the 256-bit wide datapaths for exploiting on-chip bandwidth, and the address translation unit. We present detailed simulation results on eight benchmark applications. When just a single PIM chip is used, we achieve an average speedup of 3.3X over host-only execution, due to lower memory stall times and increased fine-grain parallelism. These 1-PIM results suggest that a PIM-based architecture with many such chips yields significantly higher performance than a multiprocessor of a similar scale and at a much reduced hardware cost.
DNA Fusion Vaccines Induce Epitope-Specific Cytotoxic CD8+ T Cells against Human Leukemia-Associated Minor Histocompatibility Antigens (2006)

The graft-versus-leukemia effect of allogeneic stem-cell transplantation is believed to be mediated by T-cell recognition of minor histocompatibility antigens on recipient cells. For minor histocompatibility antigens HA-1 and HA-2, normal cell expression is restricted to hemopoietic cells, and boosting the immune response to these antigens may potentiate graft-versus-leukemia effect without accompanying graft-versus-host disease. To increase efficacy, expansion of HA-1- or HA-2-specific CTL before transplantation is desirable. However, primary HA-1- or HA-2-specific CTL expanded in vitro are often of low avidity. An alternative approach is to prime specific CTL responses in vivo by vaccination. Clearly, donor vaccination must be safe and specific. We have developed DNA fusion vaccines able to induce high levels of epitope-specific CTL using linked CD4(+) T-cell help. The vaccines incorporate a domain of tetanus toxin (DOM) fused to a sequence encoding a candidate MHC class I binding peptide. This design generates antitumor CD8(+) T-cell responses and protective immunity in preclinical models. For clinical application, we constructed vaccines encoding HLA-A*0201-restricted peptides from human HA-1 and HA-2, which were fused to DOM, and tested their performance in HLA-A*0201-transgenic mice. Priming induced epitope-specific, IFNgamma-producing CD8(+) T cells with cytotoxic function boosted to high levels with electroporation. Strikingly, these mouse T cells efficiently killed human lymphoblastoid cell lines expressing endogenous HA-1 or HA-2. High avidity is indicated by the independence of cytolysis from CD8/MHC class I interaction. These safe epitope-specific vaccines offer a potential strategy to prime HA-1- or HA-2-specific CTL in transplant donors before adoptive transfer.
Speed profile optimization for vehicles crossing an intersection under a safety constraint (2014)

This paper considers the case of two vehicles crossing an intersection from perpendicular directions. A second-order kinematic model is assumed as well as that initially both vehicles move with their maximum permissible speed. A braking/reaccelerating speed profile is proposed for the vehicle crossing second that enables it to brake without colliding with the first even if the latter unexpectedly and immediately comes to a stop. Under the aforementioned constraint, the time loss incurred by the second vehicle due to braking is used as an optimization criterion. When the profile that leads to this minimum delay is not unique, the maximum deceleration applied is used as a secondary criterion. The problem is solved analytically providing closed-form solutions.
A Multiparameter Methodology for Skin Factor Characterization: ApplyingBasic Statistics to Formation Damage Theory (2007)

The following paper describes a Skin Factor characterization methodology that has been developed and successfully applied in fields operated by BP in Colombia, South America. The method is based on basic statistic correlations that are applied for the ranking of different measured or estimated damage parameters; the primary purpose of the method is to weight the different formation damage mechanisms taking place in the complex reservoirs of the Colombian Foothills in such a way that multicomponent skin characterization maps can be estimated. The presence of compositional fluids, active tectonics environments, stacked reservoirs and well access issues all account for the above mentioned complexity.By the application of this methodology, the design of chemical stimulations has become more efficient as the output of the method, which is a Multi-Parameter characterization of the skin, is available for all the wells; in this manner, stimulation packages include components for the control of the main skin mechanisms in the ratios estimated by the model. The model is being continuously updated through the incorporation of measured and estimated damage related variables such as physical chemical analysis of back flowed samples (after stimulations), output from mineral and organic scaling index estimation models, laboratory studies and well intervention records, among others; all of them taken into account for the entire life of a particular well.Fed by the Multi-Parameter model, a skin characterization mapping tool has been developed and has become a key input in the periodically reviews of well productivity; stimulation and well intervention options are being efficiently ranked in terms of benefit leading also to a better planning of well work campaigns.
Efficacy of a Helicase-Primase Inhibitor in Animal Models of Ocular Herpes Simplex Virus Type 1 Infection (2008)

BAY 57-1293 may be more effective than valacyclovir, without the cytotoxicity or potential healing retardation seen with trifluridine. Oral BAY 57-1293 may be a substitute for eye drops as an effective treatment for herpetic keratitis and might be useful in treating stromal keratitis and iritis, as well as preventing recurrences of ocular herpes.
Modified quadratic congruence codes for fiber Bragg-grating-based spectral-amplitude-coding optical CDMA systems (2001)

We have constructed a series of new code families for the spectral-amplitude-coding optical code-division multiple-access (CDMA) system, and proposed new transmitter and receiver structures based on tunable chirped fiber Bragg gratings (FBGs). The proposed system has been analyzed by taking into account the effects of phase-induced intensity noise, shot noise, and thermal noise. We have also compared the performance of this system with that of a former system where a Hadamard code is used. It has been shown that the new code families can suppress the intensity noise effectively and improve the system performance significantly. When the effective power is large (i.e., >-10 dBm), the intensity noise is the main factor that limits the system performance. When the effective power is not sufficiently large, thermal and shot noise sources become the main limiting factors and the effect of thermal noise is much larger than that of shot noise.