gebhart/patrepeval huggingface dataset:
ODIN: Automated Drift Detection and Recovery in Video Analytics (2020)

Recent advances in computer vision have led to a resurgence of interest in visual data analytics. Researchers are developing systems for effectively and efficiently analyzing visual data at scale. A significant challenge that these systems encounter lies in the drift in real-world visual data. For instance, a model for self-driving vehicles that is not trained on images containing snow does not work well when it encounters them in practice. This drift phenomenon limits the accuracy of models employed for visual data analytics. In this paper, we present a visual data analytics system, called ODIN, that automatically detects and recovers from drift. ODIN uses adversarial autoencoders to learn the distribution of high-dimensional images. We present an unsupervised algorithm for detecting drift by comparing the distributions of the given data against that of previously seen data. When ODIN detects drift, it invokes a drift recovery algorithm to deploy specialized models tailored towards the novel data points. These specialized models outperform their non-specialized counterpart on accuracy, performance, and memory footprint. Lastly, we present a model selection algorithm for picking an ensemble of best-fit specialized models to process a given input. We evaluate the efficacy and efficiency of ODIN on high-resolution dashboard camera videos captured under diverse environments from the Berkeley DeepDrive dataset. We demonstrate that ODIN's models deliver 6x higher throughput, 2x higher accuracy, and 6x smaller memory footprint compared to a baseline system without automated drift detection and recovery.
An asynchronous pipelined lattice structure filter (2002)

We derive an asynchronous, delay-insensitive CMOS circuit to implement a finite impulse response lattice structure filter. Simulation indicates a performance in the range of 380 million multiplications and 980 million additions per second in Hewlett-Packard's 0.8 /spl mu/m technology (/spl lambda/=0.5 /spl mu/m). We obtain high throughput by using deep pipelines and buffering the carry chains of adders and multipliers. Our work demonstrates that formal design can easily yield circuits which are safe and fast.
Carbonylation of Cyclotrisilenes (2013)

Spontaneous reaction of carbon monoxide with cyclotrisilenes has been observed. Depending on the substitution pattern, the initial product of carbonylation either dimerizes or can be trapped to yield highly functionalized cyclic silenes. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Removal of Cu(II) and Ni(II) from Industrial Effluents by Brown Seaweed, Cystoseira indica (2008)

The biomass of Cystoseira indica (RB) was chemically modified by cross-linking it with epichlorohydrin (CB1, CB2), and the same was oxidized by potassium permanganate (CB3) which was later employed for the treatment of Cu(II) and Ni(II) from effluents. The results indicated that biosorption equilibriums were rapidly established in about 30 and 75 min for Cu(II) and Ni(II), respectively. The metal biosorption was strictly pH dependent, and maximum removal of metals was observed at pH 6.0. The biosorption data dovetail the Langmuir isotherm, and the process obeyed pseudo-second-order kinetics. An intraparticle diffusion based Weber−Morris model was applied to evaluate rate-limiting steps, and the results suggested that film diffusion controlled the overall biosorption process. Fourier transform infrared analysis revealed that amino, hydroxyl, carboxyl, ether, and hydroxyl functional groups were involved in the metal binding and the sorption process was dominated by complexation as well as ion exchange. The loaded biosorbent was regenerated using HCl and used repeatedly over five cycles with little loss of uptake capacity beyond the second cycle.
Non Resonant Slots for Wide Band 2D Scanning Arrays (2005)

A novel type of broadband integrated array scanning in one plane is proposed. Such arrays are aimed to meet the requirements typically set for airborne synthetic aperture radars, while allowing the highest degree of integration between the T/R modules and radiating elements. The array is composed of broadband leaky-wave slot elements radiating by means of a wedge shaped dielectric lens. As a preliminary step this paper is focused on a finite number of infinite slots radiating in an infinite medium of the same permittivity of the lens. The problem is studied through a very efficient semi-analytical spectral domain procedure based on the assumption of small width of the slots in terms of a wavelength.
Epirubicin, cisplatin, oral UFT, and calcium folinate in advanced gastric carcinoma. (1999)

UFT (uracil and tegafur in a 4:1 molar ratio) plus calcium folinate treatment has favorable activity and tolerable toxicity in patients with advanced gastric carcinoma. High response rates have been reported in patients with advanced gastric carcinoma receiving a schedule of epirubicin, cisplatin (Platinol), and protracted infusion of 5-fluorouracil (5-FU). Replacing the inconvenient infusion pump and intravenous catheter needed for protracted infusion of 5-FU, we administered oral UFT plus calcium folinate (Orzel) to 37 patients (median age, 55 years; median World Health Organization [WHO] performance status of 1) with locally advanced or metastatic gastric carcinoma. Epirubicin 50 mg/m2 and cisplatin 60 mg/m2 were administered by intravenous injection on day 1; UFT 360 mg/m2/day po was administered in conjunction with oral calcium folinate 25 mg/m2/day in divided daily doses for 21 days, followed by a 7-day rest period. Courses were repeated every 4 weeks. Among 37 evaluable patients who received a median of four courses of treatment (range, 2 to 10), two achieved a complete response and 18 a partial response, for an overall response rate of 54% (95% confidence interval, 39% to 70%). Stable disease was reported in 12 patients (32.4%) and disease progression in another five (13.5%). The median duration of survival was 10 months (range, 2 to 15+). The main toxicities were nausea/vomiting, leukopenia, diarrhea, and oral mucositis. WHO grade 3 or 4 toxicity included leukopenia in 14 patients (37.8%), nausea/vomiting in 11 (29.7%), oral mucositis in five (13.5%), and diarrhea in four (10.8%). Epirubicin, cisplatin, and oral UFT plus calcium folinate, a convenient outpatient regimen, has significant activity and tolerable toxicities in patients with gastric carcinoma.
STEM-23. INHIBITING PROTEIN PHOSPHATASE 2A INCREASES THE ANTITUMOR EFFECT OF PROTEIN ARGININE METHYLTRANSFERASE 5 INHIBITION IN MODELS OF GLIOBLASTOMA (2020)

Abstract BACKGROUND: Despite multi-model therapy of maximal surgical resection, radiation, chemotherapy, and tumor treating fields, median survival of Glioblastoma (GBM) patients is less than two years. Protein Arginine Methyltransferase 5 (PRMT5) catalyzes the symmetric di-methylation of arginine residues and is overexpressed in GBM. Inhibition of PRMT5 causes senescence of immature GBM tumor cells. LB100, first-in-class small molecule inhibitor of Protein Phosphatase 2A (PP2A) can sensitize therapy-resistant tumor cells. Here, we tested the anti-GBM effect of concurrent PRMT5 and PP2A inhibition. Methods: Patient-derived primary GBM neurospheres (GBMNS), transfected with PRMT5 target-specific siRNA were treated with LB100 and subjected to in vitro assays including PP2A activity and western blot. The intracranial mouse xenograft model was used to test the in vivo antitumor efficacy of combination treatment. Results: We found that PRMT5-depletion increased PP2A activity in GBMNS. LB100 treatment significantly reduced the viability of PRMT5-depleted GBMNS compared to PRMT5 intact GBMNS. LB100 enhanced the G1 cell cycle arrest induced by PRMT5-depletion. Combination therapy also increased the expression of phospho-MLKL. Necrostatin-1 rescued PRMT5-depleted cells from the cytotoxic effects of LB100, indicating that necroptosis caused the enhanced cytotoxicity of combination therapy. In the in vivo mouse tumor xenograft model, LB100 treatment combined with transient depletion of PRMT5 significantly decreased tumor size and prolonged mice survival, while LB100 treatment alone had no survival benefit. Conclusion: Overall, combined PRMT5 and PP2A inhibition had significantly greater antitumor effects than PRMT5 inhibition alone.
Développement d'un modèle pré-clinique à l'infection du Chikungunya (2010)

National audience
Li+‐regulated 1‐aminocyclopropane‐1‐carboxylate synthase gene expression in Arabidopsis thaliana (1996)

Summary In Arabidopsis thaliana, 1‐aminocyclopropane‐1‐carboxylate synthase (ACS) is encoded by a multigene family consisting of at least five members whose expression is induced by hormones, developmental signals, and protein synthesis inhibition. Li + , known to interfere with the phosphoinositide (PI) second messenger system by inhibiting the activity of inositol‐phosphate phosphatases, is one of the strongest inducers of ACC synthase activity in plants. Treatment of etiolated Arabidopsis seedlings with LiCl results in a rapid induction of the ACS5 gene. Also, LiCl represses the cycloheximide (CHX)‐induced accumulation of the ACS2 mRNA. The effects of Li + on the expression of ACS5 and ACS2 are specific, dose‐dependent, and can be reversed by Ca 2+ and mimicked by the protein kinase inhibitor K‐252a. The results suggest that the regulation of some ACS genes by various inducers may involve protein kinase activity, which in turn may be controlled through an inositol 1,4,5‐triphosphate (IP 3 )‐mediated Ca 2+ mobilization. Since plants contain no Li + , the cation appears to unmask pre‐existing biochemical capacity that may be utilized by various unknown transducers during plant growth and development.
Ultraviolet laser delivery using an uncoated hollow taper (2000)

We demonstrate a simple grazing-incidence-based method for ultraviolet (UV) laser delivery and direct laser-to-taper coupling using an uncoated glass hollow taper. The taper serves as a mode homogenizer that converts the strongly multimode distribution of the input laser emission into a high-quality smooth profile at the taper output. An uncoated pyrex-glass hollow taper is used for direct launching, without any intermediate focusing elements, of UV laser emission from the third harmonic ( 355 nm) of a Q-switched Nd:YAG laser into the taper. The linear hollow taper provides a laser-to-taper coupling efficiency exceeding 70%.
On Optimal Load-Memory Tradeoff of Cache-Aided Scalar Linear Function\n Retrieval (2020)

Coded caching has the potential to greatly reduce network traffic by\nleveraging the cheap and abundant storage available in end-user devices so as\nto create multicast opportunities in the delivery phase. In the seminal work by\nMaddah-Ali and Niesen (MAN), the shared-link coded caching problem was\nformulated, where each user demands one file (i.e., single file retrieval).\nThis paper generalizes the MAN problem so as to allow users to request scalar\nlinear functions of the files. This paper proposes a novel coded delivery\nscheme that, based on MAN uncoded cache placement, is shown to allow for the\ndecoding of arbitrary scalar linear functions of the files (on arbitrary finite\nfields). Interestingly, and quite surprisingly, it is shown that the load for\ncache-aided scalar linear function retrieval depends on the number of linearly\nindependent functions that are demanded, akin to the cache-aided single-file\nretrieval problem where the load depends on the number of distinct file\nrequests. The proposed scheme is optimal under the constraint of uncoded cache\nplacement, in terms of worst-case load, and within a factor 2 otherwise. The\nkey idea of this paper can be extended to all scenarios which the original MAN\nscheme has been extended to, including demand-private and/or device-to-device\nsettings.\n
Sandstone Reservoir Stimulation Using High-Temperature Deep-Penetrating Acid (2011)

Abstract Conventional mud acid (a mixture of HF and HCl) is the most commonly used acid system for the stimulation of sandstone formations. However, well known disadvantages such as fast reaction rate, precipitation and matrix deconsolidation restrict the usefulness of this type of acid. A high-temperature deep-penetrating acid system (HTDP acid) is presented in this paper. Compared with regular mud acid, the HTDP acid penetrates deeper into the formation by generating HF at a slower rate in situ. HTDP acid is one type of retarded mud acid, and it is made up of composite phosphate and fluoride salt. A new corrosion inhibitor has been developed which makes HTDP acid suitable for formations with temperatures as high as 356°F. Very important, the HTDP acid has much higher quartz solubility compared with the mud acid and could reduce precipitation. The HTDP acid has been used in 23 wells in China offshore oilfields since 2006, and 22 of the stimulation jobs have been deemed effective. Among those wells, five are high temperature/low permeability wells (the highest temperature is 293 °F) and are located in China's Bohai Bay. Two of the wells are in a loose sandstone formation in the South China Sea. The production of these wells after stimulation was enhanced remarkably. Though developed and used in China, the acid together with the high temperature inhibitor could be extrapolated to other similar sandstone reservoirs world-wide.
Hardy-Littlewood-type theorems for Fourier transforms in $\R^d$ (2022)

We obtain Fourier inequalities in the weighted $L_p$ spaces for any $1
Electron-beam SAFIER™ process and its application for magnetic thin-film heads (2004)

We have coupled the SAFIER™ (shrink assist film for enhanced resolution) process with electron-beam lithography for the fabrication of the write top pole structures for thin-film heads. The SAFIER™ process is designed to physically shrink trench patterns and contact holes with very little deterioration of the resist profile. In this article, we will present the experimental results of the SAFIER™ process for the fabrication of the write top pole. We investigate the SAFIER™ process concerning several key processing issues, including shrink resolution capability, repetition of the SAFIER™ process, shrink-sensitive baking conditions, resist sidewall profile, and line edge roughness (LER) after shrinking of the trench. The experimental results show that this process not only shrinks the size of resist trenches and contact holes, but also improves LER and critical dimension variation. We demonstrate the capability of printing top pole structures with pole widths of sub-20nm in a 0.30-μm-thick resist (aspect ratio&amp;gt;15:1), and electroplated top pole structures of 50nm in a 0.50-μm-thick resist (aspect ratio=10:1).
An SR-ISODATA algorithm for IDS alerts aggregation (2014)

Intrusion detection Systems(IDS) can produce large amount of alert data which usually possesses the characteristics of high redundancy and high repetition. Such kind of data makes the event processing for network security significantly difficult. Current cluster algorithms use cluster center to calculate the distance which leads to fairly big calculation errors. In order to aggregate the massive alert data effectively and identify important security events accurately, we propose an improved Iterative Self-Organizing Data Analysis Techniques Algorithm based on Similarity Radius (SR-ISODATA). In the presented algorithm, optimal sequence comparison method is used to calculate the attribute weight of alert data, and different similarity calculation methods are chosen due to different properties of alert data; the merging and splitting criteria are revised, the clustering center in the original ISODATA algorithm is replaced by the average similarity radius and the distance calculation in the original algorithm is replaced by the similarity. Extensive experiments using the alert experimental data on KDDCUP99 show that the SR-ISODATA algorithm gets a high alert compression rate and a higher purity of each cluster.
B cell autophagy mediates TLR7-dependent SLE and controls extramedullary hematopoiesis (BA4P.217) (2014)

Abstract Systemic Lupus Erythematosus (SLE) is a heterogeneous disease, defined by a loss of B cell self-tolerance resulting in the production of autoantibodies. One of the many mechanisms described resulting in a break in B cell self-tolerance is overexpression of the endosomal toll-like receptor, TLR7. We hypothesized that autophagy plays a crucial role in TLR7 activation in B cells by delivering ligand to endosomes. To test this model, we produced TLR7 transgenic (tg) mice with a B cell-specific (CD19-cre) ablation of autophagy (ATG5 ko), and compared SLE development to that of TLR7 tg mice with intact autophagy machinery. We observed that loss of ATG5 in B cells significantly increased the survival of TLR7 tg mice, reduced serum IgG and anti-nuclear autoantibodies, thereby preventing glomerulonephritis. These data suggest that B cell autophagy is required for TLR7-mediated SLE disease progression. However, while symptoms of SLE were ameliorated, extramedullary hematopoiesis (EMH) was dramatically increased with a splenic red pulp expansion in these mice. Thus, autophagy in B cells plays an important role in controlling lineage determination in hematopoiesis, likely by regulating chemokine and cytokine production, the mechanism by which is currently under investigation. A better understanding of the control steps involved in TLR7 activation and cytokine production could lead to improved therapeutics for treatment of SLE.
Diode-like asymmetric transmission in ultrathin hyperbolic epsilon-near-zero slabs: extreme anisotropy mimicking chirality (2018)

We demonstrate that a strong asymmetric transmission for forward and backward propagation of tilted circular polarized optical waves is supported by ultrathin epsilon-near-zero hyperbolic slabs. We find that, remarkably, this effect is solely triggered by anisotropy without resorting to any breaking of reciprocity and chiral symmetries or spatial nonlocal effects. In addition, we show that the asymmetric transmission undergoes a dramatic enhancement if the slab is hyperbolic in the epsilon-near-zero regime. This happens since, close to epsilon-near-zero point, the hyperbolic dispersion activates etalon resonances where extraordinary waves accumulate propagation phase even though the slab is ultrathin. The proposed strategy holds promise for realizing ultra-compact and efficient polarization devices at different frequency bands.
Juvenile-Onset Macular Degeneration and Allied Disorders (2014)

While age-related macular degeneration (AMD) is a leading cause of central vision loss among the elderly, many inherited diseases that present earlier in life share features of AMD. These diseases of juvenile-onset macular degeneration include Stargardt disease, Best disease, retinitis pigmentosa, X-linked retinoschisis, and other allied disorders. In particular, they can be accompanied by the appearance of drusen, geographic atrophy, macular hyperpigmentation, choroidal neovascularization, and disciform scarring just as in AMD, and often may be confused for the adult form of the disease. Diagnosis based on funduscopic findings alone can be challenging. However, the use of diagnostic studies such as electroretinography, electrooculography, optical coherence tomography, and fundus autofluorescence in conjunction with genetic testing can lead to an accurate diagnosis.
WHOIS Lost in Translation (2016)

Internet domain names expire when not renewed and may be claimed by a new owner. To date, despite existing work on abuses of residual trust after domain ownership changes, it is not well understood how often and how fast re-registrations occur, and the underlying processes are often over-simplified in scientific literature, leading to a potential bias in those studies. While in principle registration data is available in Whois databases, scalability issues and data ambiguities make re-registrations a challenging subject of study in practice. By focusing on domains about to be deleted, we were able to track 7.4 M com, net, org, biz and name domains over up to ten months to gather data for a survival analysis of re-registrations. Our results show that expiration processes may vary, and that many re-registrations happen soon after deletion, especially for older domains. We also discuss intricacies of Whois data to aid in avoiding potential pitfalls, as fast domain ownership changes combined with hidden domain states may pose challenges to operational and research communities.
Piezoresistive and Mechanical Characteristics of Graphene Foam Nanocomposites (2019)

We report the piezoresistive and mechanical characteristics of three-dimensional (3D) graphene foam (GF)–polydimethylsiloxane (PDMS) nanocomposites processed by a facile two-step approach. A polyurethane (PU) foam with graphene embedded (and aligned) in the pore walls is pyrolyzed and then impregnated with PDMS to form a GF–PDMS nanocomposite, resulting in a slitlike network of graphene embedded in the viscoelastic PDMS matrix. The interconnected graphene network not only imparts excellent electrical conductivity (up to 2.85 S m–1, the conductivity of PDMS is 0.25 × 10–13 S m–1) to the composite but also enables ultrasensitive piezoresistive behavior. For an applied compressive strain of 10% we report a 99.94% reduction in resistance, with an initial gauge factor of 178, and note that this value is significantly higher than those reported in the literature. Cyclic compression–release tests conducted at different strain amplitudes demonstrate that both the mechanical and piezoresistive responses of the GF–PDMS are fully reversible up to a maximum strain amplitude of 30%. The facile processing, recoverable, and reversible response over 1000 cycles, good hysteresis performance over a range of strain rates, and energy absorption characteristics open new opportunities for GF–PDMS nanocomposites in various applications such as soft robots and human–machine interface technologies.
True-color holographic display based on a super fast response liquid crystal film (2013)

True-color holography is presented based on RGB model using a liquid crystal film with holographic response time under an order of a microsecond. A combination of RGB reconstructions from a hologram realizes color holography.