gebhart/patrepeval huggingface dataset:
Sudden Reversible Vitritis After Keratoprosthesis (2005)

This phenomenon of sudden vitritis after KPro, with few other symptoms and with complete recovery, would be uncharacteristic of a bacterial endophthalmitis. It may represent a uveitic immune phenomenon.
Depiction of pneumothoraces in a large animal model using x-ray dark-field radiography (2018)

The aim of this study was to assess the diagnostic value of x-ray dark-field radiography to detect pneumothoraces in a pig model. Eight pigs were imaged with an experimental grating-based large-animal dark-field scanner before and after induction of a unilateral pneumothorax. Image contrast-to-noise ratios between lung tissue and the air-filled pleural cavity were quantified for transmission and dark-field radiograms. The projected area in the object plane of the inflated lung was measured in dark-field images to quantify the collapse of lung parenchyma due to a pneumothorax. Means and standard deviations for lung sizes and signal intensities from dark-field and transmission images were tested for statistical significance using Student's two-tailed t-test for paired samples. The contrast-to-noise ratio between the air-filled pleural space of lateral pneumothoraces and lung tissue was significantly higher in the dark-field (3.65 ± 0.9) than in the transmission images (1.13 ± 1.1; p = 0.002). In case of dorsally located pneumothoraces, a significant decrease (-20.5%; p > 0.0001) in the projected area of inflated lung parenchyma was found after a pneumothorax was induced. Therefore, the detection of pneumothoraces in x-ray dark-field radiography was facilitated compared to transmission imaging in a large animal model.
Advanced Volumetric Capture and Processing (2019)

Volumetric video is regarded worldwide as the next important development in media production, especially in the context of rapidly evolving virtual and augmented reality markets where volumetric video is becoming a key technology. Fraunhofer Heinrich Hertz Institute (HHI) has developed a novel technology for volumetric video. The 3D Human Body Reconstruction (3DHBR) technology captures real persons with our novel volumetric capture system and creates naturally moving dynamic 3D models, which can then be observed from arbitrary viewpoints in a virtual or augmented reality scene. The capture system consists of an integrated multicamera and lighting system for a full 360° acquisition. A cylindrical studio has been developed with a diameter of 6 m and consists of 32 20-MPixel cameras and 120 light-emitting-diode (LED) panels that allow for an arbitrary lit background. Hence, diffuse lighting and automatic keying are supported. The avoidance of green screen and provision of diffuse lighting offers the best possible conditions for relighting of the dynamic 3D models afterward at the design stage of the virtual reality (VR) experience. In contrast to classical character animation, facial expressions and moving clothes are reconstructed at high geometrical detail and texture quality. The complete workflow is fully automatic, requires about 12 hr/min of mesh sequence, and provides a high level of quality for immediate integration in virtual scenes. Meanwhile, a second, professional studio has been built up on the film campus of Potsdam Babelsberg. This studio is operated by VoluCap GmbH, a joint venture between Studio Babelsberg, ARRI, UFA, Interlake, and Fraunhofer Heinrich Hertz Institute (HHI).
Real-Time Assembly of Viruslike Nucleocapsids Elucidated at the Single-Particle Level (2019)

While the structure of a multitude of viral particles has been resolved to atomistic detail, their assembly pathways remain largely elusive. Key unresolved issues are particle nucleation, particle growth, and the mode of genome compaction. These issues are difficult to address in bulk approaches and are effectively only accessible by the real-time tracking of assembly dynamics of individual particles. This we do here by studying the assembly into rod-shaped viruslike particles (VLPs) of artificial capsid polypeptides. Using fluorescence optical tweezers, we establish that small oligomers perform one-dimensional diffusion along the DNA. Larger oligomers are immobile and nucleate VLP growth. A multiplexed acoustic force spectroscopy approach reveals that DNA is compacted in regular steps, suggesting packaging via helical wrapping into a nucleocapsid. By reporting how real-time assembly tracking elucidates viral nucleation and growth principles, our work opens the door to a fundamental understanding of the complex assembly pathways of both VLPs and naturally evolved viruses.
Rho-kinase Inhibitors: Pharmacomodulations on the Lead Compound Y-32885 (2002)

In order to specify structure-activity relationships we have synthesized new series of analogues of the Rho-kinase inhibitor (R)-(+)-N-(4-pyridyl)-4-(1-aminoethyl)benzamide (Y-32885). The structural modifications concerned the 1-aminoethyl, the pyridyl and the amide groups which are the main features of this lead compound. Our analogue derivatives were evaluated on GTPgammaS-induced contraction in permeabilized smooth-muscle and on the actin cytoskeleton. All the modifications result in a diminution or a loss of activity showing that interactions of Y-32885 with the catalytic domain of Rho-kinase seem to be particularly definite and sensitive to structural variations. The presence of a pyridine moiety and a basic amine group separated by a spacer bearing an amide function are of utmost importance.
The Synthesis of 2,1,3-Benzothiadiazine 2,2-Dioxides and 1,2,3-Benzoxathiazine 2,2-Dioxides (1965)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Synthesis of 2,1,3-Benzothiadiazine 2,2-Dioxides and 1,2,3-Benzoxathiazine 2,2-DioxidesJohn B. WrightCite this: J. Org. Chem. 1965, 30, 11, 3960–3962Publication Date (Print):November 1, 1965Publication History Published online1 May 2002Published inissue 1 November 1965https://pubs.acs.org/doi/10.1021/jo01022a521https://doi.org/10.1021/jo01022a521research-articleACS PublicationsRequest reuse permissionsArticle Views200Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Glycan Evolution in Response to Collaboration, Conflict, and Constraint (2013)

Glycans, oligo- and polysaccharides secreted or attached to proteins and lipids, cover the surfaces of all cells and have a regulatory capacity and structural diversity beyond any other class of biological molecule. Glycans may have evolved these properties because they mediate cellular interactions and often face pressure to evolve new functions rapidly. We approach this idea two ways. First, we discuss evolutionary innovation. Glycan synthesis, regulation, and mode of chemical interaction influence the spectrum of new forms presented to evolution. Second, we describe the evolutionary conflicts that arise when alleles and individuals interact. Glycan regulation and diversity are integral to these biological negotiations. Glycans are tasked with such an amazing diversity of functions that no study of cellular interaction can begin without considering them. We propose that glycans predominate the cell surface because their physical and chemical properties allow the rapid innovation required of molecules on the frontlines of evolutionary conflict.
TXRF Spectrometry as a Powerful Tool for the Study of Metallic Traces in Biological Systems (2014)

This work describes the basic principles of the Totalreflection X‐Ray Fluorescence (TXRF) spectrometry, as well as some of their most excellent applications, in the study of metal traces in different materials but mainly in biological systems. The TXRF is an analytical technique that combines the versatility and potentiality of the elemental analysis by means of X‐ray energy dispersion with an extremely low detection limits, in the order of picograms. The microanalytical capability of the TXRF allows us to analyze very small sample quantities. Both factors are of great importance in the research of metallic traces in biological systems because it allows a fast, precise and accurate characterization of the elemental fingerprint at trace level. Their successful application in studies of coordination kinetic of the new platinum based anti‐tumor drugs with the nuclear DNA, its application in the study of the metal profile of healthy and cancerous human tissues, or even its application in the study of the processes of metal diffusion through cellular membranes, turns the TXRF into a powerful tool, still to discover, within the field of biomedical sciences and general biosystems. So, the main objective of this review is to show a briefly panorama of the TXRF spectrometry and some of its more relevant applications developed up to now, mainly in the biological field, with the purpose that reader can evaluate its potential future applications.
Boron Spike Effect on Cut-Off Frequency and Early Voltage in SiGe HBTs (1995)

This paper reports an experimental study of a boron spike effect on electrical characteristics of SiGe HBTs fabricated by cold wall type ultra-high vacuum (UHV)/CVD technology. Two types of pre-treatment procedures were carried out to investigate the effect of the boron spike formed during heating step before epitaxial growth. One was Type-A (heating temperature=800°C) and the other was Type-B (HF dip and heating temperature=720°C). In Type-B, HF dip to eliminate surface contamination was necessary for reduction of heating temperature. The peak concentration of the boron spike at epi/sub interface were 1E17 cm?3 (for Type-A) and 2E16 cm?3 (for Type-B), respectively. As a result, Early voltage (V A ) was enhanced from 5V in Type-A transistor to 20V in Type-B transistor. Cut-off frequency (f T ) of Type-B transistor had smaller V CB dependence than that of Type-A.
Engine Oil Additive Effects on Deactivation of Monolithic Three-Way Catalysts and Oxygen Sensors (1994)

&lt;div class="htmlview paragraph"&gt;It is widely known that pellet-typed catalysts are deactivated by phosphorus (ZnDTP) that comes from engine oils. In this paper, the poisoning of monolithic three-way catalysts and oxygen sensors by engine oils is studied. First, catalysts and oxygen sensors were poisoned on the engine bench by test oils in which the quantity of phosphorus and ash was varied. Next, performance of the catalysts and sensors alone was examined and the vehicle exhaust emission at FTP mode was measured on a chassis dynamometer. The results indicate that phosphorus in engine oils poisons the monolithic catalyst and the oxygen sensor resulting in deterioration of the vehicle NOx exhaust emission. However, Ca sulfonate and Mg sulfonate detergents act by restraining phosphorus poisoning of the catalyst and the oxygen sensor.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;Through analysis of the catalyst and sensor surfaces, it is concluded that phosphorus poisons the catalyst and sensor forming a dense coating. But Ca and Mg prevent phosphorus from adhering to the catalysts and the sensors and from forming the dense coating.&lt;/div&gt;
Antimicrobial azobenzene compounds and their potential use in biomaterials (2016)

We recently synthesized a class of active compounds with azobenzene structure [1] and lowest in silico toxicity values. The antimicrobial activity of these molecules and their thermal stability are very promising and indicate that they may have interesting and therapeutically significant applications. This work aims to develop new materials with antibacterial and antifungal activity inserting different percentages of synthetic antimicrobial azo compounds in commercial polymer matrices. We realized thin films using solvent casting and melt compounding techniques. The obtained materials retained the proprieties of the pure matrices. This means that azo dye dissolved in the matrix does not influence the thermal behavior and the morphology of the material. Tested films exhibited the capability to inhibit biofilms formation of S. aureus and C. albicans. Spectrophotometric investigation of the azo compound released from the polymer matrices confirmed that the realized materials might be interesting for biomedical tools, antibacterial surfaces, and films for active packaging.
Prolactin Stimulates Serine/Tyrosine Phosphorylation and Formation of Heterocomplexes of Multiple Stat5 Isoforms in Nb2 Lymphocytes (1997)

Transcription factors of the Stat gene family are selectively activated by many hormones and cytokines. Stat5 originally was cloned as a prolactin-stimulated DNA-binding protein, but is also activated by non-lactogenic cytokines in many cell types. The recent identification of two distinct Stat5 genes, which encode a 94-kDa Stat5a and a 92-kDa Stat5b as well as several lower molecular weight isoforms, suggests additional complexity and combinatorial possibilities for transcriptional regulation. We now report a biochemical analysis of prolactin activation of Stat proteins in Nb2 lymphocytes, which was associated with: 1) rapid tyrosine phosphorylation of Stat5a, Stat5b, a COOH-terminally truncated 80-kDa Stat5 form, Stat1alpha, and Stat3; 2) rapid and selective formation of Stat5a/b heterodimers, without involvement of Stat1alpha or Stat3; 3) marked serine, but not threonine phosphorylation of Stat5a and Stat5b; and 4) the appearance of two qualitatively distinct Stat5 protein complexes, which discriminated between oligonucleotides corresponding to the prolactin response elements of the beta-casein and interferon regulatory factor-1 gene promoters. Collectively, our analyses showed that Stat5a and Stat5b respond similarly to prolactin receptor activation, but also suggested that the two genes have evolved unique properties that may contribute to the specificity of receptors that utilize Stat5 signaling proteins.
Photowritten optical waveguides in various glasses with ultrashort pulse laser (1997)

We show that permanent optical waveguides can be formed in various bulk glasses by photoinduced refractive index change with an ultrashort pulse laser. The waveguides were fabricated by focusing the laser beam through an microscope objective and translating the sample parallel to the axis of the laser beam. From the observations of intensity distributions in the output of guided light by a CCD camera, we demonstrated that permanent optical waveguides can be successfully formed in various glasses. In addition, from the analysis of a near-field pattern, it was confirmed that single mode waveguides of the graded index type can be formed by a writing technique using the ultrashort pulse laser.
Computer Applications to Log Interpretation: ABSTRACT (1962)

Modern stored-program electronic computers are adaptable to statistical studies and other repetitive arithmetic operations relative to log interpretation. This paper touches on several applications in practical use within the industry today. An effort is made to assess both the validity and the economics of machine computation. Machine speeds are unbelievably fast, permitting an investigation of a large spectrum of possible interpretations. It must be recognized, however, that each problem must be very well defined before taking it to the computer. This suggests that each program must evolve slowly starting with a few simple operations and decisions. Modifications are then based on previous results. In order to justify the expenditures for the programming and operation of the computer, the answers produced must be valid and of increasing utility in the search for oil. End_of_Article - Last_Page 1966------------
In-Situ Stiffness and Damping of Spread Footings and Pile Foundations in Bridges in Northern Nevada (1997)

This report presents the results of an experimental and analytical study, which was conducted on three footings of an existing bridge in order to determine their in-situ stiffness. The bridge is located on Interstate 80 south east of Verdi, Nevada. Six tests were conducted by shaking each footing in the longitudinal and the short direction. Each footing was subjected to sinusoidal vibration force, which was applied through an eccentric mass shaker. Twenty-three accelerometers were used to measure the response of the soil, bridge footings, and the bent cap of the bridge during shaking. A three-dimensional finite element model of the last two spans of the bridge was developed using the computer program COSMOS//M. Then, a linear response history analysis was performed to determine the steady state acceleration response of the three footings. During the analysis, the soil-footing interaction was modeled using a spring-dashpot model. Several refinements were applied to the response history analysis until the predicted steady state peak acceleration at the footing level matched the measured steady state peak acceleration on the corresponding footing during the dynamic field test. A design guideline and recommendations, which provide the basis for the computation of footing stiffness using spring models, were developed based on the experimental and the analytical results.
Effect of Protein Supplements Containing Urea or Natural Protein on Concentration of Trimethylamine in Cow's Milk (1978)

An attempt was made to reduce trimethylamine concentrations in milk by altering the protein supplement of the cow's rations. A gas chromatographic technique was used to analyze milk for trimethylamine. All cows were fed ad libitum a 1:1 mixture of alfalfa and prairie hay. Cows on the control ration also received a concentrate containing 43.5% sorghum grain, 43.5% corn, 10% wheat bran, and a 2.5% mineral-vitamin supplement. The protein equivalent was increased from 11% for the control ration to 17% for the other experimental rations by supplementing the ration with urea, Starea, or soybean meal. Each of three pairs of cows was fed one of the experimental rations, which was alternated with the control ration. For the fourth pair, the Starea ration was alternated with the urea ration. The urea ration reduced milk trimethylamine by 22%. Soybean meal supplementation did not appreciably affect trimethylamine in milk. Urea seemed slightly more effective than Starea in reducing concentrations of trimethylamine. To decrease trimethylamine in milk, it is recommended that urea or Starea be used as the supplementary source of protein in a cow's ration. Milk-flavor scores and trimethylamine concentrations were not related, probably because trimethylamine concentrations were well below threshold.
Eliminating tromboning mobile call setup for international roaming users (2009)

Existing mobile service providers allow their customers to receive telecommunications services when they roam to other countries. However, in the standard mobile call setup procedure, a call from the visited country to a roaming customer at that country results in two international calls. This phenomenon is referred to as the tromboning effect. In this paper, we propose a third-party solution that resolves the tromboning problem by replacing two international calls with two local calls. Besides huge saving in voice/data path, analytic modeling and simulation experiments indicate that our solution is effective in call setup signaling. Also, our solution does not need to modify the existing mobile telecommunications systems.
Using Contact-Specific Surface Area Estimates in Exposure Models (2005)

The objectives of this work are to demonstrate methods for the collection and incorporation of contact-specific surface area measurements in dermal exposure assessments and illustrate the potential difference in resulting dermal and non-dietary ingestion estimates using this type of surface area data. Continuing the work of Stanford's Exposure Research Group, categorical surface area data contained in children's sequential microlevel activity patterns were converted into quantitative coordinates, which in turn provided a foundation to map data on the skin surface. Programs were constructed to establish an accounting system of spatial coordinates, governed by categorical surface area data, to map exposure estimates or activity statistics on the skin. An illustrative example is provided that estimates the spatial variability of chlorpyrifos on the palm of a hand using contact-specific surface area data. Results show a maximum value of 14.6 ng on the fingertips and no chemical exposure along the edges of the fingers and in the center of the palm. The methodologies presented could result in more realistic estimates of concentration gradients across the skin, better representations of dermal exposure due to multiple contacts, improved approximations of nondietary ingestion, and enhanced models of dermal dose.
Multi hop communication in global wireless framework (2004)

Mobile ad-hoc networks are infrastructure-free highly dynamic wireless networks, where central administration or configuration by the user is impractical. This paper highlights the questions of allowing all the wireless ad hoc devices to use the same network address in a global wireless framework. It presents the paradigm of using auto-assigned, private non-internet-routable IP addresses as the basis to provide anytime, anywhere services to nomadic end users in the information space. It follows on from our work on integrating personal mobility services architectures and interoperating wireless networked appliances. Providing a multi-hop communication over a series of user's devices each acting as a multi-port MAC bridge constructs an interoperable, interworking domain allowing applications to run seamlessly in the upper layers. We discuss the case of the IEEE 802.11 protocol specification where we present working scenarios and protocols used to initialise and maintain the operation of its multi-hop communications. It is an attempt to provide a better range of services in an interoperable heterogeneous domain to offering the services from both the network side and the local environment by means of multi-hop ad-hoc MAC bridges.
한국 및 일본의 주류용 종국에서 분리한 국균 곰팡이의 특성 (1993)

한국과 일본으로부터 주류용 종국 19종을 시료로 수집하여 이로부터 국균곰팡이 31 strain을 분리하였다. 분리된 곰팡이를 동정한 후에 각 strain으로 쌀코지를 제조하여 당화력, 호정화력, 단백질분해력, 산생성력, 갈변 및 향을 조사하였다. 분리된 31 strain을 동정한 결과 10 strain Asp. awamori var. kawachill로, 18 strain은 Asp. oryzae로, 3 strain은 Asp. usamii mut. shirousamii로 동정되었다. 한국에서 생산된 종국은 단일 species에 단일 strain으로 된 곰팡이로 이루어져 있었으나 일본에서 생산된 종국은 서로 다른 두 species의 혼합 또는 같은 species내의 서로 다른 2∼4개의 strain의 혼합으로 이루어져 있었다. 전분 분해능력과 단백질 분해능력를 기준으로 하여 Species 별로 판단한다면 Asp. awamori var. kawachii H1, I1 및 J1, Asp. oryzae J2, L2, M2, P3 및 P4, 그리고 Asp. usamii mut. shirousamii S1이 나머지 strain들 보다 더 좋았다. 한국의 종국에서 분리된 곰팡이들이 일본의 종국에서 분리된 곰팡이들보다 전분 분해력이나 단백질 분해력이 훨씬 낮았다. 3종의 국균 곰팡이에 대힌 대표적인 특성은 Asp. awamori var. kawachii는 산생성능력은 강하나 전분 분해력과 단백질 분해력이 약하고, Asp. oryzae는 전분 분해력이 강하고 향이 좋으나 산을 거의 생산하지 못하며, Asp. usamii mut. shirousamii 단백질 분해력이 강하나 향이 좋지 않은 점이었다.