gebhart/patrepeval huggingface dataset:
Magnetic exchange interactions in nitroxyl biradicals bridged by metal-metal bonded complexes: structural, magnetochemical, and electronic spectral characterization of tetrakis(perfluorocarboxylato)dimetal(II) complexes of rhodium and molybdenum containing axially coordinated nitroxyl radicals (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMagnetic exchange interactions in nitroxyl biradicals bridged by metal-metal bonded complexes: structural, magnetochemical, and electronic spectral characterization of tetrakis(perfluorocarboxylato)dimetal(II) complexes of rhodium and molybdenum containing axially coordinated nitroxyl radicalsTimothy R. Felthouse, Teng Yuan. Dong, David N. Hendrickson, Huey Sheng. Shieh, and Michael R. ThompsonCite this: J. Am. Chem. Soc. 1986, 108, 26, 8201–8214Publication Date (Print):December 1, 1986Publication History Published online1 May 2002Published inissue 1 December 1986https://pubs.acs.org/doi/10.1021/ja00286a016https://doi.org/10.1021/ja00286a016research-articleACS PublicationsRequest reuse permissionsArticle Views345Altmetric-Citations46LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Cytokines in Viral Hepatitis (1999)

Cytokines play an important role in the defense against viral infections, both indirectly, through determination of the predominant pattern of host response, and directly, through inhibition of viral replication. However, in the context of an inflammatory response against a virus, cytokines may also lead to liver damage. The importance of this is best demonstrated in hepatitis B virus (HBV). In acute HBV infection, a vigorous polyclonal cellular immune response is critical; thus type 1 cytokine release is essential to initiating an effective immune response. The cytokines released by CD4+ and CD8+ cells also play an important role in downregulation of HBV replication, demonstrating that it is possible to control a viral infection without the death of infected cells. However, if there is a defect in the acute response, HBV becomes chronic; in that case, the presence of an ongoing suboptimal inflammatory response can activate the process of hepatic fibrosis. In hepatitis C infection, the role of cellular immune responses and cytokines is less clear. Hepatitis C may be resistant to inhibition by cytokines, so cytokines may have a more prominent role in liver damage than in controlling viral replication. Both hepatitis B and C may have specific mechanisms to inhibit cytokine production, highlighting the critical role of these molecules in recovery from infection.
bolism of the Inhibitory Neurotransmitter γ-Aminobutyric Acid in a Rabbit Model of Fulminant Hepatic Failure (1983)

The serum concentration of 7-aminobutyric acid (GABA) has been found to be elevated by more than an order of magnitude in a rabbit model of acute hepatic failure. A potential mechanism for increased serum GABA levels in liver failure is decreased catabolism of GABA. To study this possibility, GABA-transaminase activities were measured in nonneural tissues, and the kinetics of 3 H-GABA in vivo were defined in both normal rabbits and rabbits with galactosamine-induced acute liver failure. Liver failure was associated with 56 and 80% increases in the activities of GABA-transaminase in liver and kidney, respectively. In the normal rabbit following the intravenous injection of 3 H-GABA, total radioactivity in the serum decreased very rapidly initially and much more slowly after 3 to 4 min. Levels of labeled metabolites of 3 H-GABA increased very rapidly in serum and reached a plateau after 5 to 10 min. The dependence of total serum radioactivity on time was similar for rabbits 10 hr after galactosamine injection, and control rabbits, with the exception that total serum radioactivity was higher during the first 3 min of the study in galactosamine-treated rabbits. In rabbits in hepatic coma, total serum radioactivity was higher but radioactivity in metabolites was lower than in controls at corresponding times. Clearance of 3 H-GABA from the circulation (i.e., the product of the initial volume of distribution and the fractional catabolic rate, milliliters per minute) was reduced by 26% in rabbits 10 hr after galactosamine injection and by 61% in rabbits in hepatic coma. The reduction in clearance of 3 H-GABA was associated with a decrease in the initial volume of distribution but no appreciable change in the fractional catabolic rate of GABA. The magnitude of the decrease in clearance did not fully account for the increase in serum GABA concentrations observed during acute liver failure. These findings suggest that, in addition to impaired GABA metabolism, an increase in the delivery rate of GABA to the circulation occurs in acute hepatic failure. Possible mechanisms for the latter phenomenon include increases in synthesis of GABA from glutamate in the liver and/or kidney, synthesis of GABA by gut bacteria permeability of the intestine and brain to GABA.
Multidimensional Discussions on an Interactive Mobile Platform for Language Education -- A Case at the University of Hong Kong (2014)

Many lecturers in universities are held in big lecture theater which may not be the most desirable environment to carry out effective class discussions. Class, an interactive mobile learning platform developed and adopted in the University of Hong Kong, enables real-time interactive discussion among students and lecturer through their tablet PCs and smartphones and facilitates classroom discussion of various sizes and styles, gathering opinions from all classmates in an organized manner that is conducive to effective and fruitful discussions. It is a useful tool in facilitating multidimensional discussions that accommodate various types of discussion and teaching styles required in language learning. Learning no longer stresses on the one-way knowledge transmission from teachers to students, but in enhancing the capacity of the student to develop critical thinking ability to analyze issues from multiple angles in an organized and logical way. Discussions have hence become an increasingly important part of interactive learning. This system encourages more active participation from students to foster a more interactive class environment that is optimal for effective language learning and teaching.
The First Occurrence of Tomato Yellow Leaf Curl Virus in Tomato (Lycopersicon esculentum Mill.) in Japan. (1998)

A new virus disease occurred in tomato in Shizuoka and Aichi prefectures. The virus from Shizuoka was transmitted by Bemisia tabaci of B biotype, but not by sap. Its narrow host range was restricted to five species from two families. Geminate particles were observed in partially purified virus preparation from infected leaves of Datura stramonium. Specific DNA bands were detected from infected plants by polymerase chain reaction using two sets of primers designed for DNA A component of geminiviruses. The viruses from Shizuoka and Aichi had extremely high degrees of nucleotide sequence similarities (98%) with a mild isolate of tomato yellow leaf curl virus from Israel (TYLCV-Is-M). Their genomic organization of DNA A was the same as that of TYLCV. The amino acid sequence similarity between six ORFs of TYLCV-Is-M and the equivalent ORFs of the virus isolates from Shizuoka and Aichi was over 95%. From these results, the two virus isolates were identified as TYLCV and were closely related to TYLCV-Is-M from Israel. This report is the first on the occurrence of TYLCV in tomato in Japan.
System study of fault current limiter for shipboard power system (2009)

Fault current limiters are an attractive option for high fault current duty shipboard power systems. FCL's have the potential to improve safety and reliability, and limit the size and rating of protective equipment, and limit the extent of voltage sags and interruptions. This paper explores the system performance of a novel superconducting fault current limiter
A Wireless Body Sensor Platform to Detect Progressive Deterioration in Musculoskeletal Systems (2013)

Recent developments in technology have helped to reduce the physical size and weight of devices and opened up new opportunities for their application in delivering unobtrusive healthcare services. In particular, kinetic and kinematic systems, that use sensors attached to the body, are currently being used to measure and understand many different aspects of human gait and behaviour. This has been particularly useful in treating stroke patients, rehabilitation, and understanding sedentary behaviour. Nonetheless, many of these systems are only capable of providing information about rudimentary movement rather than data on the mechanics of motion itself (tendons, ligaments and so on). Therefore, the information required by healthcare professionals to treat diseases like progressive deterioration of the musculoskeletal system, i.e. arthritis, cannot be determined. This paper discusses some of the technologies currently used to assess movement and posits a novel approach based on strain gauge technology to measure the constituent parts of a joint and its movement. In this way, the mechanics of motion can be studied and used to help detect and treat musculoskeletal diseases. A case study is presented to demonstrate the applicability of our approach.
Carbon Nanotube Structures as Ionic Barriers: A New Corrosion Prevention Concept (2009)

We consider a new concept - the electronic barrier - for corrosion prevention. The barrier is an electronic p-n junction made by topping one film of functionalized carbon nanotubes on another. Potentiodynamic tests, Raman spectroscopy and inspection by scanning electron microscope revealed that the order of the layers (namely, p-n or n-p) with respect to the metal surface does determine whether the metal corrodes or not.
High-average-power diode-pumped SBR picosecond Nd vanadate laser with harmonic generation (2000)

We present a 10 W average power saturable Bragg reflector (SBR) cw modelocked laser operating at 1064 nm. The laser produces 35 ps pulses at repetition rates between 75 MHz and 250 MHz. The laser gain material used is Nd:vanadate (Nd:YVO<SUB>4</SUB>), which is pumped with 30 W from a fiber coupled diode bar operating at 808 nm. SBR modelocking provides a reliable and robust method of modelocking solid state lasers. It behaves like a high damage threshold solid state saturable absorber. The modelocking process is self- starting and requires no active cavity stabilization thus enabling turn-key operation. We present results on power stability, damage thresholds and beam quality taken over many hours of operation. In addition we present our results on efficient single pass second and third harmonic generation of this laser system using LBO and KTP.
The other triple-negative breast cancer: Immunohistochemical and clinicopathologic characterization of the Claudin-low subtype. (2011)

1129 Background: The triple-negative (TN) immunohistochemical (IHC) definition for basal-like breast cancer lacks specificity. This aggressive subtype is best identified with the addition of EGFR and CK5/6 biomarkers; however, the subgroup of TN breast cancers that lack expression of these biomarkers (5NP) is mostly uncharacterized. Recently, an additional intrinsic subtype, claudin-low, was identified using microarray-based gene expression data. These tumors are characterized by the low expression of ERBB2, ESR1, and cell-cell adhesion proteins such as claudins 3/4/7 and E-cadherin. Methods: Microarray gene expression and IHC data were collected from two independent cohorts: Washington University (WU, n=114) and University of North Carolina (UNC, n=98). Tumors were assigned as claudin-low or not using a genomic predictor. An IHC surrogate for the claudin-low subtype was developed, and applied to a tissue microarray (TMA) from the University of British Columbia (UBC, n=3473) linked with extensive clinicopathological and outcome data. Results: Against a gene expression gold standard, an IHC combination of ER(-), Her2(-), and E-cadherin(-) best identified claudin-low tumors (PPV=24% WU, 67% UNC; NPV=94% WU, 87% UNC). This IHC panel identified 226 claudin-low tumors (6.5%) from the UBC TMA. Compared to the basal-like tumors, claudin-low tumors had a similar distribution for patient age, tumor size and lymph node status. However, the claudin-low tumors were less often grade 3 (88% vs. 80%, p = 0.036) or high expressors of Ki67 (61% vs. 82%, p <0.001). Claudin-low subgroup had superior breast cancer specific survival when compared to the basal-like (10-yr BCSS 69% vs. 60%) with a multivariate HR of 0.69 (p = 0.030), adjusted for clinicopathological variables and adjuvant treatment. Conclusions: The ER(-)/Her2(-)/E-cadherin(-) IHC definition identified the claudin-low subtype of breast cancer, although with a PPV insufficient for clinical use. The addition of this definition to the standard IHC panel for intrinsic breast cancer subtypes (ER, PR, Her2, Ki67, EGFR and CK5/6) isolates a subgroup of TN tumors that are clinically distinct from basal-like breast cancers.
Computation over Compressed Structured Data (Dagstuhl Seminar 16431) (2017)

This report documents the program and the outcomes of Dagstuhl Seminar 16431 "Computation over Compressed Structured Data".
Scheduling real-time traffic with deadlines over a wireless channel (1999)

Recently, there has been widespread interest in the extension of data networks to the wireless domain. However, scheduling results from the wireline domain do not carry over to wireless systems because wireless channels have unique characteristics not found in wireline channels, namely, limited bandwidth, bursty channel errors and location-dependent channel errors.
(تحلیل گفتمان روایت جنبش مشروطه در کتاب های درسی تاریخ (دوره پهلوی و پس از انقلاب اسلامی (2015)

دو نظام سیاسی پیش و پس از انقلاب اسلامی دارای دو ایدئولوژی و گفتمان سیاسی مسلطِ متفاوت از یکدیگر بوده و هستند؛ مسائلی که تأثیر مستقیم بر نگارش کتاب‌های درسی به‌ویژه کتاب‌های درسی تاریخ گذاشته‌ است. نمونه‌ی این تاثیر در روایت‌های متفاوت ارائه شده از جنبش مشروطیت به عنوان یکی از مهم‌ترین رویدادهای تاریخ معاصر ایران است که تحت‌تأثیر مستقیم دو عاملِ گفتمان سیاسی مسلط، و نیز گفتمان‌های سیاسی-اجتماعیِ غیرمسلط این دو دوره شکل گرفته -است. بنابراین این پژوهش بر آن است تا با بررسی کتاب‌های درسی تاریخ مقطع سوم دبیرستان در دو دوره پهلوی و پس از انقلاب اسلامی، تأثیر گفتمان‌های سیاسیِ مسلط بر روایت جنبش مشروطه و ویژگی‌های خاص هر نوع روایت را بررسی کرده، و همچنین به ‌بررسی تأثیر جریان‌های بیرونی و گفتمان‌های غیر مسلطِ سیاسی- اجتماعی که در مقاطعی توانستند در کتاب‌های درسی نوع خاص و متفاوتی از روایت گفتمان‌ سیاسی مسلط را به‌ وجود آورند، بپردازد. پس هدف از این پژوهش، بررسی روایت‌های ارائه‌شده از جنبش مشروطه با کاربست روش تحلیل گفتمان می‌باشد. باتوجه به تفاوت دو گفتمان سیاسی مسلط در دو دوره پیش و پس از انقلاب اسلامی، این نوشتار نیز در دو قسمت به تحلیل محتوا و تحلیل گفتمان انواع روایت‌های جنبش مشروطه پرداخته ‌است.
Hydrogen tunneling in the activation of dioxygen by a tris(pyrazolyl)borate cobalt complex (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHydrogen tunneling in the activation of dioxygen by a tris(pyrazolyl)borate cobalt complexOlivia M. Reinaud and Klaus H. TheopoldCite this: J. Am. Chem. Soc. 1994, 116, 15, 6979–6980Publication Date (Print):July 1, 1994Publication History Published online1 May 2002Published inissue 1 July 1994https://pubs.acs.org/doi/10.1021/ja00094a080https://doi.org/10.1021/ja00094a080research-articleACS PublicationsRequest reuse permissionsArticle Views863Altmetric-Citations101LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information Get e-Alerts
Vision for road inspection (2014)

Road surface inspection in cities is for the most part, a task performed manually. Being a subjective and labor intensive process, it is an ideal candidate for automation. We propose a solution based on computer vision and data-driven methods to detect distress on the road surface. Our method works on images collected from a camera mounted on the windshield of a vehicle. We use an automatic procedure to select images suitable for inspection based on lighting and weather conditions. From the selected data we segment the ground plane and use texture, color and location information to detect the presence of pavement distress. We describe an over-segmentation algorithm that identifies coherent image regions not just in terms of color, but also texture. We also discuss the problem of learning from unreliable human-annotations and propose using a weakly supervised learning algorithm (Multiple Instance Learning) to train a classifier. We present results from experiments comparing the performance of this approach against multiple individual human labelers, with the ground-truth labels obtained from an ensemble of other human labelers. Finally, we show results of pavement distress scores computed using our method over a subset of a citywide road network.
Iterative algorithm for subaperture stitching interferometry for general surfaces (2005)

A novel iterative algorithm for subaperture stitching interferometry for general surfaces is presented. It is based on the alternating optimization technique and the successive linearization method. The computer-aided-design model of the tested surface is used to determine the overlapping region precisely. Subapertures are simultaneously stitched by minimizing deviations among them as well as deviations from the nominal surface. Precise prior knowledge of the six degrees-of-freedom nulling and alignment motion is no longer required.
Phosphorylation alters the mechanical stiffness of a model fragment of the dystrophin homologue utrophin (2022)

Duchenne muscular dystrophy is a lethal muscle wasting disease caused by the absence of the protein dystrophin. Utrophin is a dystrophin homologue currently under investigation as a protein replacement therapy for Duchenne muscular dystrophy. Dystrophin is hypothesized to function as a molecular shock absorber that mechanically stabilizes the sarcolemma. While utrophin is homologous with dystrophin from a molecular and biochemical perspective, we have recently shown that full-length utrophin expressed in eukaryotic cells is stiffer than what has been reported for dystrophin fragments expressed in bacteria. In this study, we show that differences in expression system impact the mechanical stiffness of a model utrophin fragment encoding the N terminus through spectrin repeat 3 (UtrN-R3). We also demonstrate that UtrN-R3 expressed in eukaryotic cells was phosphorylated while bacterial UtrN-R3 was not detectably phosphorylated. Using atomic force microscopy, we show that phosphorylated UtrN-R3 exhibited significantly higher unfolding forces compared to unphosphorylated UtrN-R3 without altering its actin-binding activity. Consistent with the effect of phosphorylation on mechanical stiffness, mutating the phosphorylated serine residues on insect eukaryotic protein to alanine decreased its stiffness to levels not different from unphosphorylated bacterial protein. Taken together, our data suggest that the mechanical properties of utrophin may be tuned by phosphorylation, with the potential to improve its efficacy as a protein replacement therapy for dystrophinopathies.
Voltammetric Determination of Oxygen in Liquid Metals Using Solid Oxide Electrolytes (1972)

where M was either silver or copper. Impervious electrolyte tubes were immersed in the liquid metal. The dependence of current on immersion depth, applied potential, time, dissolved oxygen concentration, temperature, and the amplitude and frequency of vibration of the electrolyte was studied. The electrode reactions are reversible. At sufficiently high applied potentials, diffusion oyerpotential appears at the liquid metal electrode and, for small depths of immersion, limiting currents are eventually realized. They are directly proportional to the concentration of dissolved oxygen meaning that voltammetric measurements could be used to determine the dissolved oxygen content of liquid metals. This proportionality was verified from 0.002 to 0.15 a/o (atomic per cent) O in silver between 1000° and 1200°C and from 0.005 to 0.13 a/o O in copper between 1100° and 1300°C. Effective diffusion layer thicknesses are about 0.05 cm.
Angiographically detectable Thebesian veins are a dynamic and reversible finding in the setting of congenital heart disease (2017)

Angiographically detectable Thebesian veins are a rare finding in patients with congenital heart disease and may represent global changes in the coronary circulation. This is the first report, adult or pediatric, to demonstrate that ThV dilation is a dynamic process capable of both progression and regression. The physiologic impact of these findings remains to be elucidated.
Performance of Blended Cements Made with Controlled Particle Size Distributions (1986)

Blended cements were prepared from two controlled particle size distribution (CPSD) cements (95% finer than 31 or 23 μm) and one normally ground cement (345 m2/kg Blaine), using the same clinker and gypsum. Pastes made with these cements blended with Class F or Class C fly ashes or ground granulated slag, and lesser amounts of ground limestone or silica fume, were tested for flow, strength development, and drying shrinkage. Three CPSD blended cements (two with Class F fly ash and one with slag, all with ground limestone) were selected for mortar and concrete tests along with two normally ground blended cements as controls. All five of these cements yielded mortars at 0.485 water/cement (W/C) with equal flow (121 ± 2%). Mortar strengths were higher at all ages with the CPSD blends than the controls. The CPSD fly ash blended cement concretes prepared at 0.50 W/C required higher cement contents for 50 to 100 mm slump than did concretes prepared with normally ground blended cement. CPSD blended cements had slightly better compressive and flexural strengths and sulfate resistance than did their normally ground counterparts. Drying shrinkage of the concretes was lower when paste contents were lower, as with the CPSD slag blended cement.