gebhart/patrepeval huggingface dataset:
Mendable polymers (2007)

Recent advances in polymer and materials chemistry have led to the development of materials that exhibit the ability to undergo repair. Depending on the structure and chemical composition of the material, the repair process can occur either as a result of external stimuli or autonomously and can be a one-time event or an indefinitely repeatable process. Several systems have been demonstrated recently in the literature; however, a larger number of polymeric systems have the potential to exhibit similar mending capability. These polymeric systems all share one property in common—reversibility, either in the polymerization process or in the cross-linking process. This Feature Article will outline the various known systems that encompass the ability to mend, either by external stimuli or autonomously. In addition, several non-reversible composite systems will be presented that exhibit one-time autonomous healing.
The microbicidal potential of visible blue light in clinical medicine and public health (2022)

Visible blue light of wavelengths in the 400-470 nm range has been observed to have microbicidal properties. A widely accepted hypothesis for the mechanism of microbial inactivation by visible blue light is that the light causes photoexcitation of either endogenous (present within the microbe) or, exogenous (present in the biological medium surrounding the microbe) photosensitizers such as porphyrins and flavins, which leads to the release of reactive oxygen species that subsequently manifests microbicidal activity. Some of the factors that have been observed to be associated with enhanced microbicidal action include increased duration of exposure, and either pre- or co-treatment with quinine hydrochloride. In case of bacteria, repetitive exposure to the blue light shows no significant evidence of resistance development. Additionally, visible blue light has exhibited the ability to inactivate fungal and viral pathogens and, multidrug-resistant bacteria as well as bacterial biofilms. Visible blue light has demonstrated efficacy in eliminating foodborne pathogens found on food surfaces and exposed surfaces in the food processing environment as well as in the decontamination of surfaces in the clinical environment to minimize the spread of nosocomial infections. We conclude from reviewing existing literature on the application of the blue light in clinical medicine and public health settings that this microbicidal light is emerging as a safer alternative to conventional ultraviolet light-based technologies in multiple settings. However, further comprehensive studies and thorough understanding of the mechanism of microbicidal action of this light in different scenarios is warranted to determine its place in human health and disease.
Calcium Metabolism in Diabetes Mellitus (1991)

Calcium metabolism was studied in patients with diabetes mellitus. Information on the dietary intake of major nutrients was gathered from 23 non-insulin-dependent diabetic patients, 42 insulin-dependent diabetic patients and 245 nondiabetic patients under hemodialysis through a questionnaire. A calcium absorption test was performed, using an isotopic technique, in 11 non-insulin-dependent diabetic patients and 4 age-matched healthy subjects. Parathyroid function was examined, using oral phosphate loading, in 6 diabetic patients and 6 age-matched control subjects. The daily dietary intake of calcium in the non-insulin-dependent diabetic patients (602 +/- 52 mg) was up to the average daily nutritional requirement (600 mg). The calcium absorption rate in these patients (54.4 +/- 13.9%) was similar to that in the healthy subjects (50.1 +/- 5.4%). The response of parathyroid hormone to phosphate loading was significantly reduced in the diabetic patients compared to the control subjects. The results suggest that calcium homeostasis in diabetic patients with normal renal function is almost conserved, despite the decreased response of parathyroid hormone to phosphate loading.
The clinical study of intensive care treatment effect on coping style in illness of peasant with mammary cancer patients (2012)

Objective To know the present situation of coping style in illness of peasants who suffered from mammary cancer,and explore the effect of intensive care treatment on coping style in illness.Methods All of 123 peasant patients suffered mammary cancer were randomized into the compared group and the obseaved group,61 patients who were not peasants were enrolled to compare the coping style with the peasant patients.The obseaved group accepted routine care and intensive care for 12 months,the compared group were given routine care only.Coping styles were evaluated at 12 weeks during the intervention.Results The the coping styles of fatalistic coping and evasive coping were significantly high in peasant patients.After 12 month intensive care,the coping styles which including emotive coping,fatalistic coping,evasive coping and seek help coping changed significantly in the obseaved group.Conclusion Fatalistic coping and evasive coping are the most common coping styles of peasant mammary cancer patients,intensive care is a good mothod to improve the coping styles of these patients.
The added value of a European Union tuberculosis reference laboratory network – analysis of the national reference laboratory activities (2008)

National reference laboratories (NRL) and other laboratories are the cornerstones of well-functioning tuberculosis programmes and surveillance activities. However, the scope and activity of NRL services for mycobacterial identification and drug susceptibility testing (DST) has not been examined in detail across the European Union (EU), nor has the added value of cooperation and networking at the European level been explored with regard to strengthening laboratory services. Therefore, the European Centre for Disease Prevention and Control (ECDC) has commissioned a survey to explore these issues and to identify areas of work that could bring added value by supporting networking activities of tuberculosis (TB) reference laboratories in the EU. Structured questionnaires were sent to TB reference laboratory experts in the EU and European Economic Area (EEA) countries, and in three additional countries selected on the basis of their networking activities with EU projects and other initiatives (Switzerland, Croatia and Israel). The compiled results describe the activities and structure of 32 NRLs (29 countries replied, a response rate of 91%). The analysis of the survey led to the following recommendations for strengthening TB laboratory services: (1) implementing of the published European standards for TB laboratory services with respect to infrastructure, national reference functions, biosafety, human resources, quality assurance, operational research (including evaluation of new medical diagnostics), accuracy and speed, appropriately trained staff; (2) ensuring that laboratories only perform activities for which they have demonstrated proficiency; (3) implement validated and standardised second-line drug susceptibility testing (DST), including drugs used to define extensively drug-resistant tuberculosis (XDR TB); (4) aiming to identify Mycobacterium tuberculosis complex (MTBC) and rifampicin (RIF) resistance in over 90% of cultures and cases from smear-positive sputum directly within one to two working days. To realise some of the above recommendations and to strengthen links of TB surveillance and microbiology activities in the EU, a list of suggested generic areas of activities for an EU network of reference laboratories is presented. Such a network would build on and link to existing networks and initiatives at the European and global level.
Spatiotemporal denoising of MR spectroscopic imaging data by low-rank approximations (2011)

This paper addresses the denoising problem associated with magnetic resonance spectroscopic imaging (MRSI), where low signal-to-noise ratio (SNR) has been a critical problem. A new scheme is proposed, which exploits two low-rank structures that exist in MRSI data, one due to partial separability and the other is due to linear predictability. Experimental results from practical data demonstrate that the proposed method provides an effective way to denoise MRSI data while preserving spatial-spectral features in a wide range of SNR values.
Effect of Traumatic Brain Injury and Nitrone Radical Scavengers on Relative Changes in Regional Cerebral Blood Flow and Glucose Uptake in Rats (2002)

Changes in regional cerebral blood flow (rCBF) and glucose metabolism are commonly associated with traumatic brain injury (TBI). Reactive oxygen species (ROS) have been implicated as key contributors to the secondary injury process after TBI. Here, pretreatment with the nitrone radical scavengers (alpha-phenyl-N-tert-butyl nitrone (PBN) or its sulfonated analogue sodium 2-sulfophenyl-N-tert-butyl nitrone (S-PBN) were used as tools to study the effects of ROS on rCBF and glucose metabolism after moderate (2.4-2.6 atm) lateral fluid percussion injury (FPI) in rats. S-PBN has a half-life in plasma of 9 min and does not penetrate the blood-brain barrier (BBB). In contrast, PBN has a half-life of 3 h and readily penetrates the BBB. Regional cerebral blood flow (rCBF) and glucose metabolism was estimated by using (99m)Tc-HMPAO and [(18)F]Fluoro-2-deoxyglucose (FDG) autoradiography, respectively, at 42 min (n = 37) and 12 h (n = 34) after the injury. Regions of interest were the parietal cortex and hippocampus bilaterally. As expected, FPI produced an early (42-min) hypoperfusion in ipsilateral cortex and an increase in glucose metabolism in both cortex and hippocampus, giving way to a state of hypoperfusion and decreased glucose metabolism at 12 h postinjury. On the contralateral side, a hypoperfusion in the cortex and hippocampus was seen at 12 h only, but no significant changes in glucose metabolism. Both S-PBN and PBN attenuated the trauma-induced changes in rCBF and glucose metabolism. Thus, the early improvement in rCBF and glucose metabolism correlates with and may partly mediate the improved functional and morphological outcome after TBI in nitrone-treated rats.
Effect of antenna location on GNSS positioning for ITS applications (2016)

The proliferation of GNSS-receiving mobile devices in the consumer market and the growth of the Intelligent Transportation Systems sector have raised a lot of interest in low-cost precise positioning. However, GNSS signal quality is degraded inside the metal body of a vehicle, which is where the antenna of a portable device is to be located. This article investigates the effect of antenna location on precise low-cost GNSS positioning for a road vehicle. We compare a roof-mounted GNSS receiver with an identical receiver having the antenna on the dashboard and a tailored smartphone also located inside the cabin; both the availability of raw carrier phase measurements and the resulting horizontal precise point positioning accuracy are evaluated. The test results show that the 90 % circular error probable is degraded by several meters inside the vehicle. Moreover, most of the evaluated accuracy metrics indicate that the low-cost GNSS receiver with antenna inside the cabin achieved a positioning accuracy at least 50 % better than the smartphone located next to it when using the same satellite systems.
The Environmental Polymorphism Registry: A Unique Resource that Facilitates Translational Research of Environmental Disease (2011)

The EPR is a unique and novel resource and is ideal for genotype-driven translational research of environmental disease. We expect that it will serve as a model for future resources. Such tools help scientists attain their ultimate goals: to identify at-risk populations and develop strategies for preventing and treating human disease.
Advanced semiconductor on insulator substrates for LP and HP digital CMOS applications (2007)

To meet HP and LP circuit requirements, increasing channel mobility is required to boost transistor performance and/or reduce Vdd for lower power dissipation without performance penalty. The ultra-thin body (UTB) devices with undoped and strained channels can be used to control the SCE and reduce the sub-threshold leakage for scaling and low power dissipation. Implementing strained-silicon is not just a substrate change; strained- Si will require much more extensive work as transistor scaling continues.
Routine Postoperative Day 1 Dismissal Following Endonasal Surgery for Pituitary Adenoma: A Single-Institution Cohort Study (2023)

Introduction: Early dismissal following uncomplicated endonasal resection of pituitary adenoma has been described as safe and feasible. Dismissal on postoperative day 1 (POD1) is standard practice at our institution, though is not widely accepted in the United States. The purpose of this study was to evaluate the safety of POD1 dismissals compared with postoperative day 2 or later (POD2+) by comparing the rates of postoperative unplanned medical care between the two cohorts. We hypothesized lower unplanned postoperative medical care rates for POD1 patients.
Resting-state dopaminergic cell firing in the ventral tegmental area negatively regulates affiliative social interactions in a developmental animal model of schizophrenia (2021)

Hyperdopaminergic activities are often linked to positive symptoms of schizophrenia, but their neuropathological implications on negative symptoms are rather controversial among reports. Here, we explored the regulatory role of the resting state-neural activity of dopaminergic neurons in the ventral tegmental area (VTA) on social interaction using a developmental rat model for schizophrenia. We prepared the model by administering an ammonitic cytokine, epidermal growth factor (EGF), to rat pups, which later exhibit the deficits of social interaction as monitored with same-gender affiliative sniffing. In vivo single-unit recording and microdialysis revealed that the baseline firing frequency of and dopamine release from VTA dopaminergic neurons were chronically increased in EGF model rats, and their social interaction was concomitantly reduced. Subchronic treatment with risperidone ameliorated both the social interaction deficits and higher frequency of dopaminergic cell firing in this model. Sustained suppression of hyperdopaminergic cell firing in EGF model rats by DREADD chemogenetic intervention restored the event-triggered dopamine release and their social behaviors. These observations suggest that the higher resting-state activity of VTA dopaminergic neurons is responsible for the reduced social interaction of this schizophrenia model.
Unveiling light collection and pump enhancement from quantum wells with plasmonic metasurfaces using power dependent measurements (2023)

Abstract Low light extraction efficiency (LEE) is the greatest limiting factor for the brightness of reduced-size light-emitting diodes (LEDs) as it limits their emission intensity. In addition, LEDs have a Lambertian emission, which requires secondary optics to control the emission directionality. Plasmonic metasurfaces can introduce a way of manipulating the generated light from LEDs to enhance their LEE and steer the emitted light by reshaping the far-field emission. Here, we fabricate resonant plasmonic metasurfaces on top of a typical blue emitting wafer consisting of InGaN/gallium nitride quantum wells developed for commercial LED devices. The metasurface is separated from the InGaN quantum wells by p-GaN and indium-tin-oxide (ITO) layers with a cumulative thickness of 110 nm. Since this distance value is close to the emission wavelength in the corresponding medium, enhanced near-fields of localized plasmonic resonances do not reach the active region. Despite this, we observe a strong influence of the metasurfaces on the far-field photoluminescence emission from the quantum wells as demonstrated by Fourier imaging. Power-dependent excitation measurements of the samples allow us to retrieve the pump and light collection enhancement factors provided by the plasmonic metasurfaces. We demonstrate that the plasmonic metasurfaces can provide a pump enhancement factor of up to 4.1 and a collection enhancement factor of up to 3.2. We have also performed simulations based on the reciprocity principle and achieved a good qualitative agreement with the experimental results.
Stability Relationships Among Analogous Molecular Addition Compounds Of Group III Elements (1958)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStability Relationships Among Analogous Molecular Addition Compounds Of Group III ElementsF. G. A. StoneCite this: Chem. Rev. 1958, 58, 1, 101–129Publication Date (Print):February 1, 1958Publication History Published online1 May 2002Published inissue 1 February 1958https://doi.org/10.1021/cr50019a003RIGHTS & PERMISSIONSArticle Views249Altmetric-Citations89LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (2 MB) Get e-Alerts Get e-Alerts
Differential effects of PDE5 inhibitors on cardiac dysfunction in the MDX ouse model of Duchenne muscular dystrophy (2013)

Background Duchenne muscular dystrophy (DMD) is the most common inherited form of muscular dystrophy, which results in skeletal muscle weakness by age 6. In its later stages DMD leads to dilated cardiomyopathy and heart failure with high level of mortality. At present there are no effective treatments for most of the cardiac pathology in DMD patients. Results
Somatomedins in Adolescence: A Cross-Sectional Study of the Effect of Puberty on Plasma Insulin-Like Growth Factor I and II Levels* (1983)

To explore the effect of puberty on the somatomedins (SMs), a group of insulin-like peptides which mediate the action of GH on skeletal tissue, we measured SM-C/insulin-like growth factor-I (SM-C/IGF-I) and IGF-II by specific RIAs in 110 adolescents between the ages of 10 and 18 yr. All subjects were in good health and between the 5th and 95th percentiles for height. In both females and males, SM-C/IGF-I levels rose during puberty to a peak approximately 3-fold higher than the average adult level. The rise in SM-C/IGF-I levels corresponded better with the Tanner stage of the adolescents than with their chronological age. IGF-II levels did not rise during puberty and were slightly below adult levels. The dramatic rise in SM-C/IGF-I levels during puberty suggests a role for this SM peptide in the adolescent growth spurt. Furthermore, these data indicate that proper interpretation of SM-C/IGF-I levels during adolescence must include a knowledge of the patient's pubertal development.
Boosting Algal Bloom by Five-Fold with AIEgens: Towards the Development of Biofactory (2020)

Human population is now faced with grand challenges such as global warming, food shortage and energy sustainability, which could be partially solved by massively increasing the growth and yield of photosynthetic organisms which capture the light energy to convert carbon dioxide and water into usable chemical energy. Cyanobacteria and eukaryotic microalgae are considered as attractive targets to be exploited by the algal factory because of their fast growth, low cost cultivation, less arable land and the diversity of high-value chemical substances produced. Many optical approaches have been introduced to increase the efficiency in artificial culturing systems, such as adding a luminescent layer that absorbs ultraviolet light and emits photosynthetic active radiation for cyanobacteria. In this work, we introduced luminogens with aggregation-induced emission characteristics (AIEgens) into the growth medium of a marine cyanobacteria. These hydrophobic AIEgens formed highly emissive luminogenic aggregates in the aqueous medium and dispersed around the cyanobacteria. Remarkedly, the number of cyanobacteria incubated in the medium with AIE aggregates was 5-fold more than the control group after 14-day culturing. The increased photosynthetic active radiation and the change of cyanobacteria protein expression in photosynthesis and metabolism might be the reason. Our study is the first using organic luminogenic aggregates as optical engineering inside the growth medium to dramatically increase the growth of cyanobacteria and demonstrated that AIEgens is promising technologies in the development of algal factories.
A study in rapid prototyping: Leveraging software and hardware simulation tools in the bringup of system-on-a-chip based platforms (2011)

Traditional use of software and hardware simulators and emulators has been in efforts for chip level analysis and verification. However, prototyping and bringup requirements often demands system or platform level integration and analysis requiring new uses of these traditional pre-silicon methods along with novel interpretations of existing hardware to prototype some functions matching behaviors of future systems. In order to demonstrate the versatility and breadth of the pre-silicon environments in our systems lab, ranging from functional instruction set software simulators to Field Programmable Gate Array (FPGA) chip logic implementations to integrated systems of existing hardware built to mimic key functional aspects of the future platforms, we present our experiences with platform level verification, analysis and early software development/enablement for an I/O attached network appliance system. More specifically, we show how simulation tools along with these early prototype systems were used to do chip level verification, early software development and even system level software testing for a System on a Chip processor attached as an I/O accelerator via Peripheral Component Interconnect Express (PCI Express) to a host system. Our experiences demonstrate that leveraging the full range of pre-silicon environment capabilities results in full system level integrated software test for a I/O attached platform prior to the availability of fully functional ASICs.
Nasolacrimal Duct Obstruction and Orbital Cellulitis Associated With Chronic Intranasal Cocaine Abuse (1999)

Chronic intranasal cocaine abuse can result in extensive bony destruction of the orbital walls with associated orbital cellulitis, and should be included in the differential diagnosis of acquired nasolacrimal duct obstruction. Anterior rhinoscopy is very helpful in establishing the correct diagnosis in these patients.
Initial measurements of two- and three-dimensional ordering, waves, and plasma filamentation in the Magnetized Dusty Plasma Experiment (2016)

The Magnetized Dusty Plasma Experiment at Auburn University has been operational for over one year. In that time, a number of experiments have been performed at magnetic fields up to B = 2.5 T to explore the interaction between magnetized plasmas and charged, micron-sized dust particles. This paper reports on the initial results from studies of: (a) the formation of imposed, ordered structures, (b) the properties of dust wave waves in a rotating frame, and (c) the generation of plasma filaments.
Clinical evaluation of carbon-11-phenylephrine: MAO-sensitive marker of cardiac sympathetic neurons. (1996)

PHEN provides PET images of human heart comparable in quality and uniformity to HED. Like HED, PHEN localizes in the sympathetic nerves of the heart. However, the more rapid efflux of PHEN, that is likely mediated by MAO, may provide information on the functional status of cardiac sympathetic neurons unobtainable with HED.