gebhart/patrepeval huggingface dataset:
BIOMETHANE PRODUCTION FROM GRAPE POMACES: A TECHNICAL FEASIBILITY STUDY Extended abstract (2013)

Agricultural wastes, obtaining by processing fruits and vegetables, nowadays are a huge environmental problem. On the other hand, they can represent sources for the production of high added value products, such as biofuels and fine chemicals. Winemaking is one of the most common fruit processing industries in the world: during the 2011 campaign 293 million hL of wine were produced, 46 million hL of which in Italy, which is the second producer of wine in the world after France (FAOSTAT, 2013). Vinification is a traditional and seasonal process which differs depending on the kind of wine to be produced. However, usually, it mainly consists of the same following phases: harvest, steaming, crushing, pressing, fermentation, sedimentation decanting, stabilization, bottling. The winemaking residues can be divided in liquid and solid ones. The former are composed by wastewaters used to clean and sterilize winery equipment. The solid wastes consist mainly of grape stalks obtained from the destemmed grapes, pomaces or marcs obtained after pressing and lees from sedimentation of the fermented grape juice. Grape pomace (GP) is the most abundant winemaking waste, and it represents about the 20% (w/w) of grapes used for the production of wine (Schieber et al., 2001). During the 2011 campaign, about 1.1 Mt of GPs were produced in Italy (FAOSTAT, 2013). GP typically consist of skins (peels), stalks and seeds. Its composition depends on a lot of parameters, among which geographic production region, clime and winemaking process. However, it is a fibrous solid waste rich in lignin, cellulose, hemicellulose and pectine due to the major presence of the fruit skin, usually characterized by 40% of TS and a low pH (around 4). GP is not rich in sugars, while it contains a high amount of tannins and polyphenols, which are high added value compounds well known for their antioxidant characteristics (Dinuccio et al. 2010; Bustamante et al. 2008). In Italy, GPs are sent to distilleries, where they are processed for the production of distillates. Alternatively, GPs could be valorized in different ways, by taking advantage of their chemical features and the presence of a lot of high added value substances. According to literature, the main obtainable products and processes applicable to GPs can be summarized as follows: (a) polyphenols extraction; (b) animal feeding; (c) composting; (d) fermentation for the production of fine chemicals; (e) incineration; (f) biomethane. In particular, the last one is produced during anaerobic digestion, which is a biological process usually referring to an oxygen-free fermentation of biomass which lead to the production of biogas, i.e., a mix of gases represented by up to 70% of methane. The anaerobic digestion for the production of biogas from GPs can be a highly attractive process for the winery industry, by coupling the opportunity of generating income from waste with that of abating disposal costs.
7A-1 SURF Imaging - A New Method for Ultrasound Contrast Agent Imaging (2007)

A new method for detection of ultrasound contrast agent micro-bubbles is presented and analyzed. The method transmits dual frequency pulse complexes (frequency separation ~ 1:10), and the signals from at least two complexes with opposite polarity of the low frequency pulse is combined to suppress the signal scattered from tissue and enhance the signal scattered from micro-bubbles. The method has larger CTR and CNR than current methods using the 2 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">nd</sup> harmonic band of the scattered signal, especially for the high frequency above the bubble resonance frequency. The methods have special interest for high frequency imaging of neo-angiogenesis in tumors and the vasa vasorum of arterial plaque.
Optical fabrication of three-dimensional polymeric microstructures (2005)

We present a technique for building three-dimensional structures using optical methods combined with photocuring chemistry. This method merges an optics-based approach with chemical restructuring through the transition of materials from distinct phases. By activating this photocurable material in combination with controlling the intensity distributions that are inherently in optical patterns, in situ fabrication of three-dimensional polymeric microstructures is demonstrated. This experimentally simple approach combined with thermal control can create complex shapes including curved and asymmetric profiles. This method has potential applications in a variety of fields including optical techniques, photoactivatable materials, and laboratory-on-a-chip systems.
Präzise Lokalisierung und Breitband-Kommunikation im 60-GHz-Band - PreLocate : Teilvorhaben: HF-Chips und Basisbandverarbeitung für Lokalisierung und Kommunikation im 60- GHz-Band (PreLocate-IHP) ; Schlussbericht ; Projektlaufzeit: 01.10.2011 bis 31.07.2014 (2015)

Fur zahlreiche Anwendungen im Bereich mobile drahtlose Kommunikation besteht der Bedarf nach einer genauen Lokalisierung mobiler Terminals. Dabei ist oft eine zentimetergenaue Lokalisierung bei gleichzeitiger Datenubertagung mit Raten von > 1 Gb/s notwendig. Auf Grund der hohen verfugbaren Bandbreite eignen sich dafur Funksysteme im mm-Wellen Bereich und insbesondere im 60-GHz-Band hervorragend.
Am IHP wurde ein HF-Chip-Satz fur 60 GHz Ubertragung mit Beamsteering-Funktionalitat entwickelt. Des Weiteren wurde ein OFDM Basisband-Prozessor fur Ubertragungsraten bis zu 3,6 Gb/s entwickelt. Dieser wurde mit einem Verfahren zur Entfernungsmessung erweitert. Die Steuerung von Datenubertragung und Entfernungsmessung erfolgt uber einen speziellen MAC Prozessor. Beide Funktionen laufen im zeitmultiplex quasi-gleichzeitig ab.
Zum Nachweis der Funktionalitat der gleichzeitigen Datenubertragung und Lokalisierung wurde ein FPGA-basierter Demonstrator entwickelt und mehrfach ausgestellt.
Hepatic steatosis in obese patients: clinical aspects and prognostic significance (2004)

Non-alcoholic fatty liver disease is a new clinicopathological condition of emerging importance, now recognized as the most common cause of abnormal liver tests. It is characterized by a wide spectrum of liver damage: simple steatosis may progress to advanced fibrosis and to cryptogenic cirrhosis through steatohepatitis, and ultimately to hepatocellular carcinoma. Obesity is the most significant single risk factor for the development of fatty liver, both in children and in adults; obesity is also predictive of the presence of fibrosis, potentially progressing to advanced liver disease. From a pathogenic point of view, insulin resistance plays a central role in the accumulation of triglycerides within the hepatocytes and in the initiation of the inflammatory cascade. Chronic hepatocellular injury, necroinflammation, stellate cell activation, progressive fibrosis and ultimately, cirrhosis may be initiated by peroxidation of hepatic lipids and injury-related cytokine release. In the last few years, several pilot studies have shown that treatment with insulin-sensitizing agents, anti-oxidants or cytoprotective drugs may be useful, but there is no evidence-based support from randomized clinical trials. Modifications in lifestyle (e.g. diet and exercise) to reduce obesity remain the mainstay of prevention and treatment of a disease, which puts a large number of individuals at risk of advanced liver disease in the near future.
Influence of Ejection Fraction on Cardiovascular Outcomes in a Broad Spectrum of Heart Failure Patients (2005)

LVEF is a powerful predictor of cardiovascular outcome in heart failure patients across a broad spectrum of ventricular function. Nevertheless, once elevated to a range above 45%, ejection fraction does not further contribute to assessment of cardiovascular risk in heart failure patients.
A comparative study of Raman enhancement in capillaries (2011)

This work reports on the comparative studies of Raman enhancement in liquid core waveguides (LCWs). The theoretical considerations that describe Raman enhancement in LCWs is adapted to analyze and compare the performance of hollow core photonic crystal fibers (HCPCFs) to conventional Teflon capillary tubes. The optical losses in both platforms are measured and used to predict their performance for different lengths. The results show that for an optimal waveguide length, two orders of magnitude enhancement in the Raman signal can be achieved for aqueous solutions using HCPCFs. This length, however, cannot be achieved using normal capillary effects. By integrating the interface of the fluidic pump and the HCPCF into a microfluidic chip, we are able to control fluid transport and fill longer lengths of HCPCFs regardless of the viscosity of the sample. The long-term stability and reproducibility of Raman spectra attained through this platform are demonstrated for naphthalenethiol, which is a well-studied organic compound. Using the HCPCF platform, the detection limit of normal Raman scattering in the range of micro-molars has been achieved. In addition to the higher signal-to-noise ratio of the Raman signal from the HCPCF-platform, more Raman modes of naphthalenethiol are revealed using this platform.
Generalized error-locating codes with component codes over the same alphabet (2017)

We consider generalized error locating (GEL) codes over the same alphabet for both component codes. We propose an algorithm for computing an upper bound on the decoding error probability under known input symbol error rate and code parameters. Is is used to construct an algorithm for selecting code parameters to maximize the code rate for a given construction and given input and output error probabilities. A lower bound on the decoding error probability is given. Examples of plots of decoding error probability versus input symbol error rate are given, and their behavior is explained.
Correlation of serum 25-hydroxyvitamin D3 and C-reactive protein with coronary artery disease (2015)

Objective
To identify the potential correlation of serum 25-hydroxyvitamin D3 [25(OH)D3] and C-reactive protein (CRP) with coronary artery disease.


Methods
We measured the serum 25(OH)D3 and CRP levels in 416 suspected coronary heart disease patients who underwent coronary angiography. Gensini scores were used to assess the severity of coronary stenosis. Based on the results of coronary angiography, the 416 patients were divided into normal group (n=246), stable angina group (n=110), and acute coronary syndrome (ACS) group (n=60).


Results
The serum levels of 25 (OH) D3 in the normal group and stable angina group were significantly higher than that in the ACS gropu [(33.15±20.95) nmol/L vs. (15.55±5.7) nmol/L, (28.93±16.45) nmol/L vs. (15.55±5.7) nmol/L, both P<0.001]. The CRP level in the normal group was significantly lower than those in the stable angina group and the ACS group [(4.33±0.12) mg/L vs. (5.68±0.25) mg/L, (4.33±0.12) mg/L vs. (5.73±0.31) mg/L, both P<0.001]. The serum 25(OH)D3 was not correlated with CRP or Gensini score in the normal group. In the ACS group, the serum 25(OH)D3 was negatively correlated with CRP level and Gensini score (r=-0.026, P=0.045; r=-0.256, P=0.048), while CRP level was positively correlated with Gensini score (r=0.459, P<0.001). In the stable angina group, the serum 25(OH)D3 was also negatively correlated with CRP level and Gensini score (r=-0.211, P=0.027; r=-0.208, P=0.029), and the latter two were positively correlated (r=0.574, P<0.001).


Conclusions
Low serum 25(OH)D3 levels are associated with coronary artery stenosis. Combining with CRP, it may be involved in the pathogenesis of coronary heart disease through inflammatory mechanism.


Key words: 
Coronary heart disease; 25-hydroxyvitamin D3; C-reactive protein
Supplementary Figure S6 from Immuno-PET Imaging of Engineered Human T Cells in Tumors (2023)

&lt;p&gt;Determination of different tumor rejection kinetics according to tumor size&lt;/p&gt;
Alphavirus Vectors for Therapy of Neurological Disorders (2012)

Alphavirus vectors engineered for gene delivery and expression of heterologous proteins have been considered as valuable tools for research on neurological disorders. They possess a highly efficient susceptibility for neuronal cells and can provide extreme levels of heterologous gene expression. However, they generally generate short-term transient expression, which might limit their therapeutic use in many neurological disorders often requiring long-term even life-long presence of therapeutic agents. Recent development in gene silencing applying both RNA interference and microRNA approaches will certainly expand the application range. Moreover, alphaviruses provide interesting models for neurological diseases such as demyelinating and spinal motor diseases.
Enzymatic Preparation of Phenolic Glucosides by Streptococcus mutans (2003)

oMost studies of transglycosylation with glucosyltransferasehave been focusing on the formation of oligosaccharides.One of the best model compounds of glucosyltransferasewas the flavonoid cathechin. Several glucosyltransferase anddifferent glucosyl donors were applied to the glucosylationof catechin.
Fidelity of Runx2 Activity in Breast Cancer Cells Is Required for the Generation of Metastases-Associated Osteolytic Disease (2004)

The osteolytic bone destruction associated with breast cancer skeletal metastases represents a serious and incurable clinical condition. However, the molecular mechanisms regulating tumor cell expression of factors involved in the generation of osteolytic disease remain elusive. We demonstrated recently that breast cancer cells express the Runx2 transcription factor, essential for bone formation and a regulator of skeletal homeostasis. Our experimental results demonstrate that perturbation of Runx2 regulatory function in tumor cells abolishes their ability to form osteolytic lesions in vivo. In vitro, we show that breast cancer cells inhibit osteoblast differentiation while concurrently enhancing osteoclast differentiation in marrow stromal cell cultures. Disruption of Runx2 activity abrogates both of these cancer cell-mediated effects on bone cells. These results demonstrate that Runx2 expression in breast cancer cells provides a molecular phenotype that enables the interactions between tumor cells and the bone microenvironment that lead to osteolytic disease.
Conformational and Electronic Properties of a Microperoxidase in Aqueous Solution: A Computational Study (2005)

A theoretical study of the conformational properties of a small heme peptide in aqueous solution is carried out by classical, long-timescale molecular dynamics simulations. The electronic properties of this species, that is, the relative energies of its excited electronic states and the redox potential, are reproduced and related to the conformational behavior using the perturbed matrix method and basic statistical mechanics. Our results show an interesting coupling between the conformational transitions and the electronic properties. These investigations, beyond the biophysically relevant results addressing the long-standing question of the actual role of the enzyme structure on the enzyme activity, are also of some methodological interest since they offer a further computational perspective for including the electronic degrees of freedom into the modeling of rather complex molecular systems.
Decomposition and Reconstruction of Signal in Real-Time Spectral Analysis (2007)

In recent years, wavelet transform which gives expression in time-frequency domain has been adopted for a nonstationary process. Authors have proposed a new spectral analytical method in time-frequncy domain. In the conventional spectral analytical methods, the decomposition and the reconstruction of signals have been obtained analytically. The proposed method consists of two approaches. We call these approaches as Approach 1 and Approach 2. In this paper, we show the decomposition and reconstruction of signal based on Approach 1. First, we show that the signal is decomposed to the signal elements. They are called the decomposition waves, and all these decomposed waves are added to obtain the reconstructed wave. Next, we show that the magnitude characteristic and the phase characteristic between the original signal and the reconstructed wave. Then the conditions between the signal and the reconstructd wave are derived to realize a sufficiently approximated wave. By a numeric calculation example, we show the approximation ability by the proposed method.
Methoden zur Pulverpräparation für technische Keramiken (1990)

Abstract Ceramic materials have been known for several thousands of years, but an intensive research in the last two decades was leading to the advanced materials which are becoming established in todays technology and which are expected to form the backbone of developments to the next century. The properties of the final ceramics are greatly predeterminated by the characteristics of the starting powder materials. This situation stimulated the increase of studies on preparation of taylor made powders with regard to purity, homogeneity, reactivity, grain size and grain size distribution. Starting with the classical solid state reaction a detailed review is given of wet chemical preparation techniques for perovskite type materials. Briefly some physical methods of powder preparation are mentioned. Furthermore important processes accompanying the preparation as drying, control of agglomeration behaviour and powder characterization are discussed, respectively.
An Asynchronous Many-Task Implementation of In-Situ Statistical Analysis using Legion. (2015)

In this report, we propose a framework for the design and implementation of in-situ analy- ses using an asynchronous many-task (AMT) model, using the Legion programming model together with the MiniAero mini-application as a surrogate for full-scale parallel scientific computing applications. The bulk of this work consists of converting the Learn/Derive/Assess model which we had initially developed for parallel statistical analysis using MPI [PTBM11], from a SPMD to an AMT model. In this goal, we propose an original use of the concept of Legion logical regions as a replacement for the parallel communication schemes used for the only operation of the statistics engines that require explicit communication. We then evaluate this proposed scheme in a shared memory environment, using the Legion port of MiniAero as a proxy for a full-scale scientific application, as a means to provide input data sets of variable size for the in-situ statistical analyses in an AMT context. We demonstrate in particular that the approach has merit, and warrants further investigation, in collaboration with ongoing efforts to improve the overall parallel performance of the Legion system.
Compact Resonant Slot Array Antenna Using Partial H-Plane Waveguide (2010)

In this letter, a resonant slot array antenna using a compact partial H-plane waveguide is proposed. To design the antenna, the conductance value of a longitudinal shunt slot on the partial H-plane waveguide is numerically estimated using a commercial electromagnetic (EM) simulator and the analytic conductance equation. The partial H-plane slot array antenna behaves as a resonant 1-D structure with longitudinal shunt slots and has almost the same characteristics as a conventional waveguide slot antenna even though it has a one-quarter cross section. The antenna is fabricated in the S-band, and the measured results are in good agreement with simulated results.
Lyophilization results in cleavage of the active-site histidine bridge in the four-copper form of bovine erythrocyte superoxide dismutase (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLyophilization results in cleavage of the active-site histidine bridge in the four-copper form of bovine erythrocyte superoxide dismutaseKenneth G. Strothkamp and Stephen J. LippardCite this: J. Am. Chem. Soc. 1982, 104, 3, 852–853Publication Date (Print):February 1, 1982Publication History Published online1 May 2002Published inissue 1 February 1982https://pubs.acs.org/doi/10.1021/ja00367a037https://doi.org/10.1021/ja00367a037research-articleACS PublicationsRequest reuse permissionsArticle Views77Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A distributed look-ahead algorithm for scheduling interdependent tasks (2002)

Autonomous decentralized systems, which concurrently work on different types of jobs consisting of interdependent tasks (steps), are considered. A dynamic decentralized look-ahead scheduling algorithm and a cooperation protocol are proposed. The goal is to utilize information about the internal job structure concerning future service requirements and system state information for dynamically arranging schedules such that jobs can take advantage of inevitable waiting times of others. The algorithm is evaluated by simulations. Waiting time reductions in sample configurations of up to 75% for single job types at the expense of only slightly worse response times for other job types compared to systems not applying the algorithm demonstrate the algorithm's success.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Constitutive Activation of Proto-Oncogen Protein p21 Induces Cell Cycle Arrest in the G1 Phase in Contact-Inhibited Vascular Endothelial Cells. (2002)

In an attempt to find a strategy to modulate the proliferation of vascular endothelial cells, we examined whether constitutive activation of proto-oncogen protein p21 (Ras) induced the reentry of confluent human umbilical vascular endothelial cells (HUVECs) into the S phase. When an adenovirus construct expressing a constitutively active Ras mutant (Ad/RasG12V) was infected into HUVECs, their morphology changed strikingly and they appeared to be transformed. However, Ad/RasG12V-infected HUVECs did not enter the S phase, as determined by assessing 3H-thymidine incorporation. In accordance with the above results, the expression of cyclin A both at the transcript and protein levels did not increase in Ad/RasG12V-infected HUVECs relative to that in control cells, although the expression of cyclin D1 was induced in Ad/RasG12V-infected cells. Interestingly, the expression of the cyclin-dependent kinase (CDK) inhibitor p21cip1 was remarkably increased while that of p27kip1 did not decrease in Ad/RasG12V-infected HUVECs. Furthermore, CDK2 activity was not induced in Ad/RasG12V-infected HUVECs. These results suggested that the constitutive activation of Ras promoted the reentry of confluent HUVECs in the G0 phase into the G1 phase, but not into the S phase. The results also indicated that the constitutive activation of Ras might have induced the persistent expression of p21cip1 and p27kip1, and that this induction of p21cip1 and p27kip1 expression possibly caused the cell cycle arrest at the G1 phase.