gebhart/patrepeval huggingface dataset:
Triple-peaked scintillation pulse-height spectra for MeV axially channeled ions in NaI(Tl) (1977)

Previous experiments with aligned positive-ion beams on NaI(Tl) showed that the scintillation pulse-height spectrum exhibits two characteristic peaks: one due to those particles that are never channeled, and one at higher pulse height due to those particles that remain in a channeled trajectory throughout their range. This paper reports experiments with improved instrumental resolution. Pulse-height spectra for $^{4}\mathrm{He}$, $^{7}\mathrm{Li}$, $^{12}\mathrm{C}$, $^{16}\mathrm{O}$, and $^{32}\mathrm{S}$ ions aligned along the $〈100〉$ axis of NaI(Tl) were recorded in the MeV range. In certain cases a clearly defined intermediate third peak was observed. The third peak is attributed to a maximum in the dechanneling probability per unit length as a function of penetration depth. Data are analyzed in terms of a parameter describing the stability of the channeling trajectory.
Prediction or Not? An Energy-Efficient Framework for Clustering-Based Data Collection in Wireless Sensor Networks (2010)

For many applications in wireless sensor networks (WSNs), users may want to continuously extract data from the networks for analysis later. However, accurate data extraction is difficult-it is often too costly to obtain all sensor readings, as well as not necessary in the sense that the readings themselves only represent samples of the true state of the world. Clustering and prediction techniques, which exploit spatial and temporal correlation among the sensor data provide opportunities for reducing the energy consumption of continuous sensor data collection. Integrating clustering and prediction techniques makes it essential to design a new data collection scheme, so as to achieve network energy efficiency and stability. We propose an energy-efficient framework for clustering-based data collection in wireless sensor networks by integrating adaptively enabling/disabling prediction scheme. Our framework is clustering based. A cluster head represents all sensor nodes in the cluster and collects data values from them. To realize prediction techniques efficiently in WSNs, we present adaptive scheme to control prediction used in our framework, analyze the performance tradeoff between reducing communication cost and limiting prediction cost, and design algorithms to exploit the benefit of adaptive scheme to enable/disable prediction operations. Our framework is general enough to incorporate many advanced features and we show how sleep/awake scheduling can be applied, which takes our framework approach to designing a practical algorithm for data aggregation: it avoids the need for rampant node-to-node propagation of aggregates, but rather it uses faster and more efficient cluster-to-cluster propagation. To the best of our knowledge, this is the first work adaptively enabling/disabling prediction scheme for clustering-based continuous data collection in sensor networks. Our proposed models, analysis, and framework are validated via simulation and comparison with competing techniques.
Asymptotically Optimal Planning by Feasible Kinodynamic Planning in a State–Cost Space (2016)

This paper presents an equivalence between feasible kinodynamic planning and optimal kinodynamic planning, in that any optimal planning problem can be transformed into a series of feasible planning problems in a state-cost space, whose solutions approach the optimum. This transformation yields a meta-algorithm that produces an asymptotically optimal planner, given any feasible kinodynamic planner as a subroutine. The meta-algorithm is proven to be asymptotically optimal and a formula is derived relating expected running time and solution suboptimality. It is directly applicable to a wide range of optimal planning problems because it does not resort to the use of steering functions or numerical boundary-value problem solvers. On a set of benchmark problems, it is demonstrated to perform, using the expansive space tree (EST) and rapidly-exploring random tree (RRT) algorithms as subroutines, at a level that is superior or comparable to related planners.
Absence of Effect of Stimulants on the Pharmacokinetics of Desipramine in Children (1999)

We conducted a retrospective chart review to examine the pharmacokinetic interaction between desipramine and the stimulants methylphenidate and dexedrine using routinely monitored desipramine serum concentrations in children receiving desipramine either alone or with a stimulant. Subjects were 142 children and adolescents (age 6-17 yrs; 113 taking desipramine, 29 taking desipramine-stimulants) in whom 401 dose- and weight-normalized serum concentrations were evaluated (333 desipramine, 68 desipramine-stimulants). Desipramine pharmacokinetic parameters were similar for both groups, including mean weight-corrected dose (3.66+/-1.36 mg/kg, desipramine; 3.66+/-1.09 mg/kg, desipramine-stimulants; p=0.97), weight- and dose-normalized serum concentrations (47.26+/-39.26 [microg/L]/[mg/kg], desipramine, 39.02+/-19.92 [microg/L]/[mg/kg], desipramine-stimulants; p=0.09), and clearance (0.690+/-0.913 [L/kg]/hr, desipramine; 0.613+/-0.514 [L/kg]/hr, desipramine-stimulants; p=0.499). When stratified by age, gender, and type of stimulant, no difference was detected (p>0.05) between groups. Our findings indicate the absence of a clinically significant interaction between desipramine and stimulants.
Characterization of the Role of Phenolic Compounds in the Inhibition of α‐Amylase by Kombucha Tea (2016)

Kombucha is a tea blend that is fermented by a symbiotic culture of bacteria and yeast (SCOBY), and is of high interest in the United States for its health benefits. Research indicates that Kombucha can improve resistance against cancer, prevent cardiovascular disease, promote digestive functions, reduce inflammatory problems, and lower blood glucose levels. The hypoglycemic activity is the primary focus of this study. Kombucha brewed in black tea contains phenolics and this class of molecules has previously demonstrated inhibitory effects on α‐amylase. Previous research indicated that unfermented black tea is not appreciably inhibitory and thus it was hypothesized that the black tea phenolics undergo biotransformation during fermentation. In order to discriminate the specific inhibitory molecules found in Kombucha, Mock Tea (MT) replicates were made containing no tea polyphenols and compared to fermented Black Tea (BT) replicates. After fermentation, the replicates were treated to remove glycosides and separated over C18 resin. Three fractions were collected and measured for α‐amylase inhibition and polyphenolic content. Prior to evaluation of the data, the pH of the tea was neutralized to negate the effect of inhibition due to acidity. The results demonstrate an acid‐independent inhibition of α‐amylase by BT but not MT (−30% activity at 2.5% (v/v) analyte in most inhibitory fractions). This does not correlate to black tea phenolic content, as the phenolic content of the BT was or lower than that of the MT in most inhibitory fractions (BT=4.7ug/mL vs. MT= 37.6 ug/mL). However, this may be correlated to oxidative biotransformation of the black tea phenolics as polar fractions resulted in BT dependent inhibition and increased phenolic content (−50% activity at 2.5% (v/v) analyte with phenolic concentrations of BT= 106.3 ug/mL vs. MT= 62.8 ug/mL). While this indicates that the mechanism of α‐amylase inhibition is indeed dependent on black tea components, it is likely there are multiple inhibitory molecules with diverse chemical properties. Furthermore, it appears that the SCOBY synthesizes hydrophobic phenolic compounds, but the molecules are not inhibitors of α‐amylase.
Preliminary experimental study on ultrasonic assisted diamond turning Ti6Al4V alloy (2015)

15th International Conference of the European Society for Precision Engineering and Nanotechnology, EUSPEN 2015, 1-5 June 2015
An analysis of errors and their causes in system programs (1975)

Program errors detected during internal testing of the operating system DOS/VS form the basis for an investigation of error distributions in system programs. Using a classification of the errors according to various attributes, conclusions can be drawn concerning the possible causes of these errors. The information thus obtained is applied in a discussion of the most effective methods for the detection and prevention of errors.
Superficial zone cellularity is deficient in mice lacking lubricin: a stereoscopic analysis (2016)

Increased Caspase-3 activation is observed in Prg4 deficient mice compared to Prg4 sufficient littermates. Absence of Prg4 induces loss of chondrocytes in the superficial and upper intermediate zone of mouse cartilage that is quantifiable by a novel image processing technique.
Pre-CABG assessment of coronary stenosis with FFR-CT predicts future graft failure (2023)

Abstract Funding Acknowledgements Type of funding sources: Public Institution(s). Main funding source(s): National Institute of Cardiology grant. Objectives To evaluate, whether a pre-CABG coronary computed tomography based FFR (FFR-CT) result at the site of a future anastomosis would predict the graft failure in patients undergoing CABG. Background Functional guidance of surgical coronary revascularization remains debatable. Recently FFR-CT is recognized as suitable for the diagnosis of vessel-specific ischemia. Methods In 43 patients (mean age 65.14y (± 9.91), 15 women) who had CCTA performed less than 6 months prior to the isolated CABG, follow-up CCTA were acquired &amp;gt;12 months post CABG procedure (at median of 903[IQR:468–1669] days). Based on the pre-CABG CCTA, FFR-CT values were simulated. On the basis of follow-up CCTA the anastomosis sites and the graft patency were determined. The graft failure was defined as either its stenosis &amp;gt;50% or occlusion. Results 98 (44 saphenous, 54 LIMA/RIMA) grafts were assessed. 18 graft from 16 patients were dysfunctional on follow-up CCTA. FFR-CT values measured at the location of the future anastomosis were significantly higher in the dysfunctional than normal grafts (0.77[0.71–0.81] vs 0.60[0.56–0.66] respectively, p = 0.0007). According to multivariable Cox regression model pre-CABG FFR-CT (HR=1.1;95%CI:1.0–1.1, p = 0.0230), and bypass graft to RCA (HR=3.7; 95%CI:1.4–9.3 vs. LAD) were independent predictors of graft dysfunction during follow-up. The optimal threshold of FFR-CT to predict graft failure was &amp;gt;0.68 (sensitivity 88.9% (95%CI:65.3–98.6), specificity 63.7% (95%CI:52.2–74.2), PPV 35.6% (95%CI:28.3%-43.5%), NPV 96.2% (95%CI:87.2%-99.0%). Conclusions Pre-CABG functional FFR-CT predicts future coronary bypass graft failure. This shows utility of FFR-CT for guiding coronary revascularization and also suggests significance of physiological assessment prior to CABG.
Two-dimensional SERS encoding method for on-bead peptide sequencing in high-throughput bioanalysis (2019)

We developed a ready-to-read on-bead peptide encoding method for high-throughput screening bioassays. With two-dimensional surface-enhanced Raman scattering nano-identifiers (2D-SERS IDs) which are concurrently labelled with two SERS codes (coupling steps and kinds of amino acid), we could possibly generate more than 10 trillion codes with only 30 Raman label compounds.
High peak power, high-energy, high-average power pulsed fibre laser system with versatile pulse duration and shape (2013)

The rapid development of commercial multi-kW continuous-wave fibre lasers and high-peak power fibre lasers leads to a natural convergence toward high-average power high-peak power pulsed fibre lasers whose applications include marking, trimming, micromachining, precision drilling, welding and cutting while retaining the characteristics advantage of the fibre laser such as compactness, high-efficiency, reliability and maintenance-free operation.
Bioactive Egg Components and Inflammation (2015)

Inflammation is a normal acute response of the immune system to pathogens and tissue injury. However, chronic inflammation is known to play a significant role in the pathophysiology of numerous chronic diseases, such as cardiovascular disease, type 2 diabetes mellitus, and cancer. Thus, the impact of dietary factors on inflammation may provide key insight into mitigating chronic disease risk. Eggs are recognized as a functional food that contain a variety of bioactive compounds that can influence pro- and anti-inflammatory pathways. Interestingly, the effects of egg consumption on inflammation varies across different populations, including those that are classified as healthy, overweight, metabolic syndrome, and type 2 diabetic. The following review will discuss the pro- and anti-inflammatory properties of egg components, with a focus on egg phospholipids, cholesterol, the carotenoids lutein and zeaxanthin, and bioactive proteins. The effects of egg consumption of inflammation across human populations will additionally be presented. Together, these findings have implications for population-specific dietary recommendations and chronic disease risk.
Path planning and topology optimization for biomimetic three-dimensional bioprinting (2014)

Tissue engineering is a highly promising multi-disciplinary field for development of biological substitutes to replace or enhance the functions of damaged tissue or organs. Traditionally, highly porous scaffolds have been used for most of the tissue engineering applications. However, the challenges in seeding the cells into a scaffold and possible immunogenic reactions of scaffold materials have led to a new method of bioprinting with live cells. With the recent advancement in bio-additive manufacturing, cells with or without biological active molecules and biomaterials can be bioprinted layer-by-layer to form three-dimensional (3D) tissue constructs. In this research work, novel biomodeling and path planning methods for bioprinting are proposed so three-dimensional tissue structures could be biomimetically printed with live cells directly from medical images. First, the medical images of the targeted tissue are imaged and segmented to convert computer tomography (CT) or magnetic resonance imaging (MRI) images to a mesh model. For path planning and optimization, the generated mesh models need to be converted to computer-aided (CAD) models. The captured mesh models are converted into smooth parametric surfaces by developed novel biomodeling algorithms. Then, several bioprinting strategies are proposed to bioprint live multi-cellular aggregates using the created computer models. Because mechanically weak cellular aggregates need to be supported perfectly at each layer, several support structure generation algorithms are proposed. The proposed methods are used to make bioprinted cellular aggregates conserve their planned 3D form, while providing sufficient conditions for cell fusion. The proposed algorithms are implemented and several example tissue structures are bioprinted by directly controlling a bioprinter with the generated commands. The results show that multicellular aggregates and their support structures can be bioprinted biomimetically in the form of the biomodeled tissues.
Alcohol Intake is Associated with Increased Risk of Squamous Cell Carcinoma of the Skin: Three US Prospective Cohort Studies (2016)

The association between alcohol intake and cutaneous squamous cell carcinoma (cSCC) is unclear. We studied the association between alcohol intake and incident invasive cSCC in three cohorts of women and men with repeated assessments of alcohol intake in the US. Information on alcohol intake was collected repeatedly during follow-up. Cumulative average of alcohol intakes was used. Multivariable Cox proportional hazards models with time-dependent exposure were used to estimate relative risks (RRs) and 95% confidence intervals, followed by a meta-analysis. During a follow-up of 4,234,416 person-years, 2,938 cSCC were identified. Alcohol intake was associated with an increased risk of cSCC with a dose-response relationship. Each additional drink (12.8 gram of alcohol) per day was associated with a 22% increased risk of cSCC (RR 1.22, 95% confidence interval: 1.13-1.31). White wine consumption of ≥5 times/wk was associated with an increased risk of cSCC (RR 1.31, 95% confidence interval: 1.09-1.59). We found no increased risk of cSCC with other alcoholic beverages. The population-attributable risk associated with alcohol intake of ≥20 grams/d was 3% of cSCCs. In conclusion, alcohol intake was associated with an elevated risk of cSCC. Among alcoholic beverages, white wine was associated with cSCC.
Optimum Storage Allocation for a File with Open Addressing (1973)

File organizations utilizing key-to-address transformation and open addressing are studied. A simulation method and a Markov model, which were used for evaluation, are presented. The cost of retrieval as a function of storage space and accesses is also formulated. The minimum of the combined costs for different operational conditions is determined.
Recycle Bioreactor for Bioethanol Production from Wheat Starch II. Fermentation and Economics (2001)

Abstract Bioethanol has been produced using sugars from cold hydolysis of pure wheat starch, sterile wheat flour, and unsterile wheat flour. The conversion of sugars to ethanol from pure starch reached 96% of the theoretical maximum while that from sterile wheat flour was 69% and from unsterile wheat flour only 35%. These data indicate that sequential hydrolysis and fermentation of wheat flour is not feasible. However, the simultaneous cold hydrolysis and fermentation of both wheat starch and wheat flour proved successful. Both sugar sources produced 95% of the theoretical maximum amount of ethanol. The process could be repeated in a sequential batch fashion for over 110 h of operation, achieving high ethanol yields in each run. A scale-up design of bioethanol production using sequential batch, simultaneous cold starch hydrolysis, and fermentation indicates that this process would be economically feasible. High levels of revenue are generated from both the bioethanol and the byproduct: food-grade wheat gluten. The payback period is predicted to be < 2 years with a discounted cash flow rate of return of 46%. Keywords: Cold Hydrolysis Fermentation Ethanol Plant Design Starch Granules Economics
Performance comparison of centralized versus distributed error recovery for reliable multicast (2000)

We examine the impact of the loss recovery mechanism on the performance of a reliable multicast protocol. Approaches for loss recovery in reliable multicast can be divided into two major classes: centralized (source-based) recovery and distributed recovery. For both classes we consider the state of the art: for centralized recovery, an integrated transport layer scheme using parity multicast for error recovery (hybrid ARQ type 2) as well as timer-based feedback suppression, and for distributed recovery, a scheme with local data multicast retransmission and feedback processing in a local neighborhood. We also evaluate the benefits of combining the two approaches into distributed error recovery (DER) with local retransmissions using a type 2 hybrid ARQ scheme. The schemes are evaluated for up to 10/sup 6/ receivers under different loss scenarios with respect to network bandwidth usage and completion time of a reliable transfer. We show that using DER with type 2 hybrid ARQ gives best performance in terms of bandwidth and latency. For networks, where local retransmission is not possible, we show that a centralized protocol based on type 2 hybrid ARQ comes close to the performance of a protocol with local retransmissions.
Alumina Duplex Coating by Multiprocesses: Air Plasma Spraying and Plasma Enhanced Chemical Vapor Deposition (2001)

Abstract Thick alumina coatings produced by Air Plasma Spraying have an interconnected porosity, thus the use of these coatings in oxidizing or corrosive environment is not suitable. In this paper, a study is developed in order to limit this problem on metallic substrates. It consists in using two successive techniques: APS and PECVD. Two parameters have been shown to be important: the roughness and the preheating temperature. Two types of duplex (PECVD coating as top coat or as bond coat) have been achieved on two substrates (TA6V and stainless steel 316L). The optimization of each process has shown that the substrate has to be grit blasted and preheated (360°C for PECVD and 250°C for APS). This study has revealed that a good (36 ± 5 MPa) APS coating adhesion was obtained on smooth TA6V substrates (due probably to a chemical reaction between TiO2 and alumina) while for stainless steel substrates, the Ra has to be at least 2µm to achieve 66 ± 5. When observing the first APS splats sprayed on the PECVD alumina smooth layer, they exhibited a specific appearance: low flattening degree (about 2 against 5 on metallic substrates) with most of the alumina in the splat rim or some sort of lace morphology. However, as a whole, the adhesion of the APS coating on the PECVD one was excellent: 60 + 4. An electrochemical method has shown that the PECVD layer on APS coating has reduced drastically its open porosity.
Identification of four IgE‐reactive proteins in raspberry (Rubus ideaeus L.) (2008)

IgE-reactive proteins in raspberry (Rubus ideaus L.) were identified using PCR, RT-PCR, 2-DE and MS/MS peptide sequencing. Specific polyclonal antibodies and patient sera were used in Western blotting to identify crossreactive epitopes. Initially, two potential allergens Rub i 1 and Rub i 3 were detected using PCR, showing high sequence identity to proteins in Rosaceous species like Mal d 1 and Mal d 3 from apple, Pru av 1 and Pru av 3 from cherry and Pru p 1 and Pru p 3 from peach. Furthermore, de novo identified peptides of a protein band at about 30 kDa reacting with most of the patient sera tested (> 80%) revealed a high sequence homology with class III chitinases. Raspberry chitinase, when subjected to glycoproteomic analysis, showed typical complex plant-type N-glycans with a core alpha1,3 fucose and a beta1,2 xylose at least at one position, indicating the presence of crossreacting carbohydrate determinants (CCDs). Finally, MS/MS analysis revealed an IgE-reactive raspberry cyclophilin, homologous to Bet v 7. Results obtained suggest that the consumption of raspberries might be responsible for adverse reactions in sensitised individuals.
Redoxaktive Nanoröhren aus Vanadiumoxid (1998)

Anders als die viel kleineren Kohlenstoffnanoröhren erhält man VOx-Nanoröhren (Bild rechts) als Hauptprodukt einer direkten chemischen Synthese bei recht niedrigen Temperaturen. Die Röhrenwände sind mehrschichtig, und zwischen den Schichten befinden sich Templatmoleküle, die durch Kationenaustausch unter Erhaltung der Röhren entfernt werden können.
Second-Generation Electronic Nose (2007)

A report discusses the second generation of the JPL Electronic Nose (ENose), an array of 32 semi-specific chemical sensors used as an event monitor to identify and quantify contaminants released into breathing air by leaks or spills. It is designed to monitor the environment for changes in air quality, and is trained to identify and quantify selected chemical species at predetermined concentrations, ranging from sub-ppm to ppth. This system has improved reproducibility for making matched arrays, allowing use of data analysis software with minimal recalibration on sensor set replacement. The Second Generation (SG) ENose is a follow-up to the first JPL Electronic Nose that was tested on an earlier space shuttle mission (STS-95). Improvements have been made to the hardware, sensor materials, and data analysis software.