gebhart/patrepeval huggingface dataset:
Extreme-Scale Model-Based Time Series Management with ModelarDB (Invited Talk) (2021)

To monitor critical industrial devices such as wind turbines, high quality sensors sampled at a high frequency are increasingly used. Current technology does not handle these extreme-scale time series well [Søren Kejser Jensen et al., 2017], so only simple aggregates are traditionally stored, removing outliers and fluctuations that could indicate problems. As a remedy, we present a model-based approach for managing extreme-scale time series that approximates the time series values using mathematical functions (models) and stores only model coefficients rather than data values. Compression is done both for individual time series and for correlated groups of time series. The keynote will present concepts, techniques, and algorithms from model-based time series management and our implementation of these in the open source Time Series Management System (TSMS) ModelarDB[Søren Kejser Jensen et al., 2018; Søren Kejser Jensen et al., 2019; Søren Kejser Jensen et al., 2021] . Furthermore, it will present our experimental evaluation of ModelarDB on extreme-scale real-world time series, which shows that that compared to widely used Big Data formats, ModelarDB provides up to 14× faster ingestion due to high compression, 113× better compression due to its adaptability, 573× faster aggregatation by using models, and close to linear scale-out scalability. ModelarDB is being commercialized by the spin-out company ModelarData.
The SARS-Unique Domain (SUD) of SARS Coronavirus Contains Two Macrodomains That Bind G-Quadruplexes (2009)

Since the outbreak of severe acute respiratory syndrome (SARS) in 2003, the three-dimensional structures of several of the replicase/transcriptase components of SARS coronavirus (SARS-CoV), the non-structural proteins (Nsps), have been determined. However, within the large Nsp3 (1922 amino-acid residues), the structure and function of the so-called SARS-unique domain (SUD) have remained elusive. SUD occurs only in SARS-CoV and the highly related viruses found in certain bats, but is absent from all other coronaviruses.
Intestinal absorption under the influence of vasopressin: studies in unanaesthetised rats. (1979)

Experiments were carried out in different segments of the intestine of unanaesthetised rats to assess the effect of vasopressin on intestinal absorptive processes. The following data were observed. (1) Within a physiological range of doses (Aziz, 1969), ADH diminished the net sodium absorption mainly by reducing the unidirectional sodium influx, whereas the behaviour of the efflux was not uniform. (2) The unidirectional volume fluxes showed the same behaviour as did the sodium fluxes. (3) ADH produced an oral-aboral gradient (jejunum greater than ileum greater than colon). (4) ADH did not significantly change the transfer of actively transported sugars; it did influence, however, passively transported substances. (5) During the intravenous application of ADH, a substance was secreted into the perfusion solution which diminished the absorption of volume and electrolytes. (6) Cyclic AMP acted on intestinal absorption in the same way as did ADH. In view of these results two mutually independent transport pathways for sodium and water are supposed, one of which is influenced by ADH or cAMP. Based on a two membrane model, an ADH mechanism is discussed: the permeability of the luminal membrane system is enhanced in the presence of vasopressin.
Conditioned Pain Modulation (CPM) is Reduced in Irritable Bowel Syndrome (2019)

This systematic review summarises evidence assessing endogenous pain inhibition in people with irritable bowel syndrome (IBS) compared with healthy controls using conditioned pain modulation (CPM) and offset analgesia (OA). Evidence regarding the role of psychological variables is also examined. The review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. Four electronic databases were searched to retrieve studies assessing CPM or OA in adults diagnosed with IBS according to the ROME II/III criteria. Standardized mean differences were calculated for each study and a random effects model was used for meta-analysis. Eleven studies were included, 5 of which reported results on the relationship between CPM and psychological variables. None of the studies assessed OA. The risk of bias assessment found a lack of assessor blinding in all studies. The pooled effect estimate was 0.90 (95% CI, 0.40-1.40) indicating a significantly lower CPM effect in people with IBS compared with controls. This effect was reduced to 0.51 when 1 outlier was excluded from the analysis. In addition, reduced CPM responses were significantly correlated with higher anxiety (r=0.17 to 0.64), stress (r=0.63), and pain catastrophizing (r=0.38) in people with IBS; however, the evidence available was limited and the strength of these associations variable. Depression was not found to be associated with CPM in these IBS cohorts. The results of this review suggest that people with IBS, as a group, demonstrate reduced pain inhibition measured by CPM. The preliminary evidence about the association between psychological factors and CPM warrants further investigations.
An analytical poroelastic model for ultrasound elastography imaging of tumors (2018)

The mechanical behavior of biological tissues has been studied using a number of mechanical models. Due to the relatively high fluid content and mobility, many biological tissues have been modeled as poroelastic materials. Diseases such as cancers are known to alter the poroelastic response of a tissue. Tissue poroelastic properties such as compressibility, interstitial permeability and fluid pressure also play a key role for the assessment of cancer treatments and for improved therapies. At the present time, however, a limited number of poroelastic models for soft tissues are retrievable in the literature, and the ones available are not directly applicable to tumors as they typically refer to uniform tissues. In this paper, we report the analytical poroelastic model for a non-uniform tissue under stress relaxation. Displacement, strain and fluid pressure fields in a cylindrical poroelastic sample containing a cylindrical inclusion during stress relaxation are computed. Finite element simulations are then used to validate the proposed theoretical model. Statistical analysis demonstrates that the proposed analytical model matches the finite element results with less than 0.5% error. The availability of the analytical model and solutions presented in this paper may be useful to estimate diagnostically relevant poroelastic parameters such as interstitial permeability and fluid pressure, and, in general, for a better interpretation of clinically-relevant ultrasound elastography results.
4 Dissolution Testing (2008)

Dissolution can be defined as a process by which the drug substance in a formulation dissolves into solution. Although dissolution appears to be a simple process, developing a suitable dissolution test requires careful considerations of the physicochemical properties of the drug substance, excipients, dosage form designs, dissolution media, and other important variables.
Fractal Quantification of the Microvasculature Heterogeneity in Cutaneous Melanoma (1999)

It is possible to differentiate and quantify clearly the differences in the microvessel profile organization using the fractal and multifractal methods.
Computerized Cognitive Rehabilitation of Attention and Executive Function in Acquired Brain Injury: A Systematic Review (2015)

Preliminary evidence suggests improvements in cognitive function following computerized rehabilitation for acquired brain injury populations including traumatic brain injury and stroke. Further studies are needed to address methodological issues (eg, small sample size, inadequate control groups) and to inform development of guidelines and standardized protocols.
IL-4 is more effective than IL-13 for in vitro differentiation of dendritic cells from peripheral blood mononuclear cells (2005)

Dendritic cells (DCs) are the most potent professional antigen-presenting cells which can activate T cells to induce the primary immune response. For clinical studies, DCs are often differentiated in vitro from peripheral blood mononuclear cells (PBMCs) through treatment with granulocyte macrophage colony-stimulating factor (GM-CSF) and IL-4. However, IL-13, a cytokine closely related to IL-4, has also been reported to induce differentiation equally or more efficiently when used with GM-CSF. For the present study, we compared the DC characteristics exhibited by iDCs and LPS-matured DCs differentiated from PBMCs using GM-CSF and IL-4 or IL-13. Physical characteristics examined include cellular morphology and surface phenotype. Functional traits investigated include FITC-dextran uptake, IL-10 and IL-12 production, allostimulation and cytokine production by stimulated T cells and antigen-specific T cell stimulation. Compared with IL-13-derived DCs, IL-4 treatment yielded more differentiated DCs, with extensive dendrites and higher expression of DC-SIGN, DEC-205, CD86 and HLA-DR. In addition, IL-4 DCs were more efficient at inducing allogeneic T cell proliferation and immature IL-4 DCs had higher endocytic activity at low FITC-dextran concentrations (1 microg ml(-1)). Although IL-13 was capable of generating DCs from PBMCs, it was not as effective as IL-4 in generating DC phenotype and functionality. Thus, the use of GM-CSF and IL-4 is the more efficient treatment for inducing DC differentiation from PBMCs.
Long-term orbit perturbations of the Draim four-satellite constellations (1992)

Long-term orbit perturbations of the Draim four-satellite constellations were investigated. Results from the 10-yr integration indicate that the orbit variations due to luni-solar perturbations are significant for the two selected orbits with 27- and 48-h periods. The resulting degradation in ground coverage was found to be 16 and 32% for the 27- and 48-h orbit constellations, respectively. Argument of perigee, inclination, and eccentricity controls must be applied to maintain 100% continuous coverage. The maximum AV required for a 10-yr mission was estimated to be 835 m/s. A strategy to avoid the costly stationkeeping maneuvers was examined, and the resulting performance improvements were assessed.
Scanning Probe Microscopy with Landmark Referenced Control for Direct Biological Investigations (2003)

We report the successful use of continuous wavelet transforms applied to atomic force microscope data sets for landmark recognition of biological features. The data sets were images of mixed red and white blood cells. Contrast enhancement followed by continuous wavelet transform of the data was used to successfully distinguish erythrocytes from neutrophil and monocyte leukocytes within the mixed cell images. All of the above are spherical objects between 6 and 8 microns in diameter, which demonstrates the ability to sort similar biological objects into distinct classes. The implications for development of on-line scanning probe recognition microscopy are discussed.
Fast Recovery for a CELP-Like Speech Codec After a Frame Erasure (2007)

The adaptive codebook used in code-excited linear prediction (CELP)-like speech codecs is very effective for modeling the quasi-periodic component of the excitation signal but, unfortunately, introduces a strong interframe dependency that renders the decoder vulnerable to frame erasures. For voiced speech, the error affects not only the erased frame but also all the subsequent frames. In this paper, a technique to improve the recovery after a frame erasure is proposed. The technique consists in a constrained excitation search at the encoder and a resynchronization procedure at the decoder. The constraint aims at reducing the contribution of the adaptive codebook by making the innovation codebook partially model the pitch excitation. Further, for highly voiced frames, the pitch-related information contained in the innovation excitation is exploited at the decoder to speed up the resynchronization of the adaptive codebook after a frame erasure. When applied to the adaptive multirate wideband (AMR-WB) codec, the method brings a significant improvement in the case of frame erasures, at the cost of a minor quality loss compared to the standard codec at the same bit rate. The method does not need additional delay and has the advantage of maintaining full interoperability between the standard codec and its modified version.
Atom-molecule kinetics. The H+ClF3 reaction (1973)

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Higher Dietary Inflammatory Index Scores Are Associated With Stress and Anxiety in Dormitory-Residing Female University Students in the United Arab Emirates (2022)

Dormitory-residing university students are at-risk of mental health problems related to unhealthy diets. The purpose of this study was to assess the association between dietary inflammatory potential and mental health of dormitory-residing female university students. This cross-sectional study was comprised of 260 undergraduate females residing in dormitories of the largest university in United Arab Emirates during Spring 2019. The Energy-adjusted Dietary Inflammatory Index (E-DII<sup>TM</sup>) scores calculated from 37 food parameters were derived from two 24-h dietary recalls. The logistic regression analysis was used to estimate odds ratios (ORs) and 95% CIs for the E-DII score in relation to depression, anxiety, and stress. The E-DII scores (mean = 2.98 ± 1.17) were categorized into: tertile 1 (-1.96-2.62), tertile 2 (2.63-3.52), and tertile 3 (3.53-5.60), representing less to more proinflammatory diets. Students in the E-DII tertile 3 had significantly higher depression, anxiety, and stress scores. The logistic regression analysis showed that each point increase in the E-DII score was associated with symptoms of stress (OR = 1.41; 95% CI: 1.12-1.77; <i>p</i> = 0.003) and anxiety (OR = 1.35; 95% CI: 1.07-1.69; <i>p</i> = 0.01). Relative to students in the E-DII tertile 1, those students in the E-DII tertile 3 were more likely to be at higher risk of stress and anxiety OR<sub>E-DIItertile3vs1</sub> = 2.89 (1.44-5.79) and 2.88 (1.49-5.56), respectively. Overall, stress and anxiety were associated with proinflammatory diets in dormitory-residing female university students, suggesting the need for targeted interventions to increase the anti-inflammatory capacity of diet and improve mental wellbeing in students on university campuses.
Forming a Predictable Flexural Mechanism in Reinforced Wall Elements (2014)

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Assessment of sleep/wake patterns using a non-contact biomotion sensor (2008)

We evaluate a contact-less continuous measuring system measuring respiration and activity patterns system for identifying sleep/wake patterns in adult humans. The system is based on the use of a novel non-contact biomotion sensor, and an automated signal analysis and classification system. The sleep/wake detection algorithm combines information from respiratory frequency, magnitude, and movement to assign 30 s epochs to either wake or sleep. Comparison to a standard polysomnogram system utilizing manual sleep stage classification indicates excellent results. It has been validated on overnight studies from 12 subjects. Wake state was correctly identified 69% and sleep with 88%. Due to its ease-of-use and good performance, the device is an excellent tool for long term monitoring of sleep patterns in the home environment in an ultraconvenient fashion.
Palladium−Tetraphosphine as Catalyst Precursor for High-Turnover-Number Negishi Cross-Coupling of Alkyl- or Phenylzinc Derivatives with Aryl Bromides (2006)

The system combining the tetraphosphine cis,cis,cis-1,2,3,4-tetrakis(diphenylphosphinomethyl)cyclopentane (Tedicyp) and [Pd(C3H5)Cl]2 has been found to be a very active catalyst for the cross-coupling of aryl bromides with alkyl- or arylzinc derivatives (Negishi reaction). A variety of aryl bromides react in good yields and high turnover numbers (TONs) (up to 800 000) with diethylzinc, n-butylzinc bromide, or n-hexylzinc bromide in the presence of 0.1−0.0001 mol % catalyst in most cases.
Segregated assemblies in bridged electron-rich and electron-poor π-conjugated moieties (2006)

We report a general strategy for the spontaneous segregation of electron-rich and electron-poor pi-conjugated moieties using mutually phobic aliphatic fluorocarbon-hydrocarbon interactions.
Synthesis of Rhamnolipid Derivatives Containing Ester Isosteres (2020)

Rhamnolipids are biosurfactants with many applications, arising from their inherent biological activity and their potential as bioremediation agents. Herein, we report the synthesis of four rhamnolipid derivatives in which the ester linkage connecting the two lipid chains in the natural compound is replaced with amide, ketone, ether, or hydrocarbon functional groups. Such compounds are anticipated to have enhanced hydrolytic stability and thus be useful probes of rhamnolipid-mediated biology and biotechnology.
Selection of search terms based on user profile (1992)

A number of researchers have addressed the problem of selecting additional search terms for a query using term dependency information. Some other techniques rely on the construction of user profiles and the identification of individual users with a class of users having known backgrounds. In other words, these latter techniques for the construction of user profiles do not consider user preferences at the level of individual users. In this paper, we present a new technique for the construction of a user profile in the form of a concept (construct) dependence tree. This technique makes use of personal construct theory that involves active user participation. The user profile captures the user preferences and may be used to select additional search terms. Our initial results indicate that the dependence tree generated by this technique can improve retrieval effectiveness.
A comparison of the properties of rice husk ash, silica, and calcium carbonate filled 75 : 25 NR/EPDM blends (2008)

Abstract The effects of incorporation of three different fillers, i.e., rice husk ash (RHA), silica, and calcium carbonate (CaCO 3 ), over a loading range of 0–60 phr on the curing characteristics, processability, mechanical properties, and morphology of 75 : 25 natural rubber (NR)/ethylene‐propylene‐diene monomer (EPDM) blends were studied using a conventional vulcanization system. Filler loading and type influence the processability of the blends in which RHA and CaCO 3 offer better processing advantage over silica. The best improvement in the tensile and tear strength and abrasion resistance of the 75 : 25 NR/EPDM blends with additional fillers was achieved when filled with silica. However, RHA and CaCO 3 were better in resilience property compared to that of silica. The RHA filled blends showed higher failure properties and abrasion resistance but lower ozone resistance than that containing CaCO 3 . Scanning electron micrographs revealed that the morphology of the blend filled with silica is finer and more homogenous compared to the blend filled with RHA and CaCO 3 . According to these observations, RHA can be used as a cheaper filler to replace CaCO 3 in rubber blends where improved mechanical properties are not so critical. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008
Chiral Mesophases of 12-Hydroxyoctadecanoic Acid in Jelly and in the Solid State. II. A New Type of Mesomorphic Solid State (1981)

Abstract A new type of chiral solid mesophase was obtained by evaporating the solvents from solutions or jellies of chiral 12-hydroxyoctadecanoic acid (12HOA). The mesomorphic solids exhibited some optical properties characteristic of a helicoidal mesophase: (1) spherulitic or Schlieren texture under a polarizing microscope, (2) reflective circular dichroic band, and (3) induced circular dichroic spectra with a single sign due to achiral molecules added to the solid. From the circular dichroic and X-ray studies, it was concluded that the helicoidal mesophase structure exists locally as small domains with a chiral smectic structure within the mesomorphic solids. Microscopic observation revealed that, upon heating, the transition of the mesomorphic solid to the crystalline solid occurred. This process was studied by differential scanning calorimetry. Formation of a variety of helicoidal systems from chiral molecules such as 12HOA and polypeptides was regarded as a phenomenon characteristic of chiral assemblies of amphiphilic molecules.
Estimate of the Globing Warming Caused by the Retreat of Polar Sea Ice (2018)

The growing concentrations of the greenhouse gases CO2, CH4 and N2O (GHG) in the atmosphere are often considered as the dominant cause for the global warming during the past decades. The reported temperature data however do not display a simple correlation with the concentration changes since 1880 so that other reasons are to be considered to contribute notably. An important feature in this context is the shrinking of the polar ice caps observed in recent years. We have studied the direct effect of the loss of global sea ice since 1955 on the mean global temperature estimating the corresponding decrease of the terrestrial albedo. Using a simple 1-dimensional model the global warming of the surface is computed that is generated by the increase of GHG and the albedo change. A modest effect by the GHG of 0.08 K is calculated for the period 1880 to 1955 with a further increase by 0.18K for 1955 to 2015. A larger contribution of 0.55 +/-0.05 K is estimated for the melting of polar sea ice (MSI) in the latter period, i.e. it notably exceeds that of the GHG and may be compared with the observed global temperature rise of 1.0 +/- 0.1 K during the past 60 years. Our data also suggest a delayed response of the mean global temperature to the loss of sea ice with a time constant of approximately 20 years. The validity of the theoretical model and the interrelation between GHG-warming and MSI-effect are discussed.
Properties of β-galactosidase of Lactobacillus kefiranofaciens K-1 isolated from kefir grains (1992)

Journal Article Properties of β‐galactosidase of Lactobacillus kefiranofaciens K‐1 isolated from kefir grains Get access K. Itoh, K. Itoh Laboratory of Animal Products Chemistry, Faculty of Agriculture, Tohoku University, 1‐1 Tsutsumidoriamamiyamachi, Aoba‐ku, Sendai 981 Search for other works by this author on: Oxford Academic Google Scholar T. Toba, T. Toba Laboratory of Animal Products Chemistry, Faculty of Agriculture, Tohoku University, 1‐1 Tsutsumidoriamamiyamachi, Aoba‐ku, Sendai 981 Search for other works by this author on: Oxford Academic Google Scholar T. Itoh, T. Itoh Search for other works by this author on: Oxford Academic Google Scholar S. Adachi S. Adachi Laboratory of Animal Products Chemistry, Faculty of Agriculture, Tohoku University, 1‐1 Tsutsumidoriamamiyamachi, Aoba‐ku, Sendai 981*Shoukei Women's Junior College, 4–10‐1 Yurigaoka, Natori 981‐12, Japan Search for other works by this author on: Oxford Academic Google Scholar Letters in Applied Microbiology, Volume 15, Issue 5, 1 November 1992, Pages 232–234, https://doi.org/10.1111/j.1472-765X.1992.tb00771.x Published: 01 November 1992 Article history Received: 02 June 1992 Accepted: 03 July 1992 Published: 01 November 1992
Introduction to the Special Section on Multiview Video Coding (2007)

The 11 papers in this special section focus on multiview video coding.
ChemInform Abstract: Preparation and Spectroscopic Characterization of CF3‐Substituted Amides, Phosphides, and Arsenides, M(CF3)‐ 2 (M: N, P, As). (1989)

Abstract The alkalimetal amide (III), phosphides and arsenides (VI) are prepared according to the scheme.