gebhart/patrepeval huggingface dataset:
Cross‐linking emulsion copolymerization of butyl acrylate with diallyl maleate (2005)

Abstract The emulsion copolymerization of butyl acrylate (BA) with a trifunctional cross‐linker, diallyl maleate (DAM), was investigated. The effect of the monomer feeding time and the amount of cross‐linker on the microstructural properties (branching, cross‐linking, gel formation, and sol MWD) of the seeded semicontinuous emulsion copolymerization of BA with DAM was investigated. It was found that the gel content was not significantly affected by increasing feeding time, but the level of quaternary carbons (an indication of the branching density) increased. On the other hand, increasing the amount of DAM in the feed composition caused gel content, level of quaternary carbons, and the cross‐linking density to increase. Interestingly, the level of quaternary carbons and the cross‐linking density sharply increased during the cooking period. The molecular weight of the sol decreased as DAM increased in the feed. In addition, the effect of process type, batch versus semibatch, was also considered and important differences in the level of quaternary carbons, cross‐linking, and gel content were found. © 2005 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 43: 4684–4694, 2005
Synthesis studies relating to guaiane sesquiterpenes (1971)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis studies relating to guaiane sesquiterpenesJames A. Marshall and Andrew E. GreeneCite this: J. Org. Chem. 1971, 36, 15, 2035–2042Publication Date (Print):July 1, 1971Publication History Published online1 May 2002Published inissue 1 July 1971https://doi.org/10.1021/jo00814a001Request reuse permissionsArticle Views951Altmetric-Citations20LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (1 MB) Get e-Alertsclose Get e-Alerts
Measurement of suction pressure dynamics of sea lampreys, Petromyzon marinus (2021)

Species-specific monitoring activities represent fundamental tools for natural resource management and conservation but require techniques that target species-specific traits or markers. Sea lamprey, a destructive invasive species in the Laurentian Great Lakes and conservation target in North America and Europe, is among very few fishes that possess and use oral suction, yet suction has not been exploited for sea lamprey control or conservation. Knowledge of specific characteristics of sea lamprey suction (e.g., amplitude, duration, and pattern of suction events; hereafter 'suction dynamics') may be useful to develop devices that detect, record, and respond to the presence of sea lamprey at a given place and time. Previous observations were limited to adult sea lampreys in static water. In this study, pressure sensing panels were constructed and used to measure oral suction pressures and describe suction dynamics of juvenile and adult sea lampreys at multiple locations within the mouth and in static and flowing water. Suction dynamics were largely consistent with previous descriptions, but more variation was observed. For adult sea lampreys, suction pressures ranged from -0.6 kPa to -26 kPa with 20 s to 200 s between pumps at rest, and increased to -8 kPa to -70 kPa when lampreys were manually disengaged. An array of sensors indicated that suction pressure distribution was largely uniform across the mouths of both juvenile and adult lampreys; but some apparent variation was attributed to obstruction of sensing portal holes by teeth. Suction pressure did not differ between static and flowing water when water velocity was lower than 0.45 m/s. Such information may inform design of new systems to monitor behavior, distribution and abundance of lampreys.
Grossularine-1 and grossularine-2, alpha carbolines from Dendrodoa grossularia, as possible intercalative agents. (1987)

Dendrodoine A, grossularines-1 and -2, metabolites isolated from the tunicate Dendrodoa grossularia, have exhibited a cytotoxic activity on L1210 leukemia cells in culture. The inhibition of DNA synthesis induced by grossularines and the plane structure of the alpha-carboline common moiety were in favor of an intercalative process for their mechanism of action. In fact, the results of viscometry, fluorescence quenching and DNA melting experiments clearly indicated the intercalative properties of grossularine-2 explained by its quasi-planar structure and the non-intercalative DNA binding of grossularine-1 explained by the presence of a bulky indole chain at the 2-position of the alpha-carboline ring.
The Synthesis of Novelcis-α-Substituted-β-aminotetralins (2003)

Abstract Teteralones were converted, in 1 to 3 steps, to α-substituted tetralones. Subsequent reductive amination with ammonium acetate/sodium cyanoborohydride gave the corresponding α-substituted-β-aminotetralins, on a multigram scale, with minimal chromatography for the entire transformation.
DNA Marker Tightly Linked to the Double Flower Locus in Rosa X Damascena Mill. F. Trigintipetala Suitable for Marker Assisted Breeding (2022)

The present study reports the development of a DNA marker tightly linked to the double flower (DF) phenotype in R. × damascena, suitable for marker assisted breeding. The development of this marker is based on previous identification of genome region associated with the DF phenotype in R. × damascena and recent studies demonstrating involvement of the AP2/TOE gene in the formation of DF in several species from the Rosaceae family. We identified a polymorphic region named RdDF upstream of the AP2/TOE gene in R. × damascena and used the sequence data for designing PCR primers. Segregation analysis of the four alleles of RdDF in a population of 104 plants obtained after self-pollination of R. × damascena showed that one of the alleles (RdDF-B, 203 bp) is tightly linked to the DF phenotype. Analysis of the segregation of two SSR markers located at a distance of approximately 1578 kb and 1129 kb on both sides of RdDF, showed that walking away from the developed RdDF marker results in the observation of simple flower recombinant plants, supporting association of RdDF with the DF phenotype. The application of the developed RdDF marker for marker assisted selection (MAS) and breeding programmes involving R. × damascena, as well as further study of the molecular base of DF formation in this species are discussed.
Evaluation of Neck Lymph Node Metastasis on Contrast-Enhanced Ultrasound: An Animal Study (2016)

CEUS can play a role in discriminating metastatic from hyperplastic lymph nodes in head and neck carcinoma.
Long-Distance Control of Origin Choice and Replication Timing in the Human β-Globin Locus Are Independent of the Locus Control Region (2000)

DNA replication in the human beta-globin locus is subject to long-distance regulation. In murine and human erythroid cells, the human locus replicates in early S phase from a bidirectional origin located near the beta-globin gene. This Hispanic thalassemia deletion removes regulatory sequences located over 52 kb from the origin, resulting in replication of the locus from a different origin, a shift in replication timing to late S phase, adoption of a closed chromatin conformation, and silencing of globin gene expression in murine erythroid cells. The sequences deleted include nuclease-hypersensitive sites 2 to 5 (5'HS2-5) of the locus control region (LCR) plus an additional 27-kb upstream region. We tested a targeted deletion of 5'HS2-5 in the normal chromosomal context of the human beta-globin locus to determine the role of these elements in replication origin choice and replication timing. We demonstrate that the 5'HS2-5-deleted locus initiates replication at the appropriate origin and with normal timing in murine erythroid cells, and therefore we conclude that 5'HS2-5 in the classically defined LCR do not control replication in the human beta-globin locus. Recent studies also show that targeted deletion of 5'HS2-5 results in a locus that lacks globin gene expression yet retains an open chromatin conformation. Thus, the replication timing of the locus is closely correlated with nuclease sensitivity but not globin gene expression.
Synthesis of 6H‐pyrazolo[2,3‐a][1,3,5]benzotriazepines (1983)

Abstract Treatment of 5‐amino‐1‐(2‐aminophenyl)‐1 H ‐pyrazole‐4‐carbonitrile ( 15 ) with triethyl orthoformate produces 6 H ‐pyrazolo[2,3‐ a ][1,3,5]benzotriazepine‐3‐carbonitrile ( 16 ). Other members of this novel ring system result from treating 15 with triethyl orthoacetate and triethyl orthopropionate. These latter reactions, which yield homologs 17 and 19 , respectively, of 16 , also produce acyclic Schiff bases. These Schiff bases are useful in determining the position of the triazepine double bond in pyrazolobenzotriazepines 16 , 17 and 19 , using 13 C nmr spectroscopy.
Light Scattering by a Finite Obstacle and Fano Resonances (2008)

The conditions for observing Fano resonances at elastic light scattering by a single finite-size obstacle are discussed. General arguments are illustrated by consideration of the scattering by a small (relative to the incident light wavelength) spherical obstacle based upon the exact Mie solution of the diffraction problem. The most attention is paid to recently discovered anomalous scattering. An exactly solvable one-dimentional discrete model with nonlocal coupling for simulating diffraction in wave scattering in systems with reduced spatial dimensionality is also introduced and analyzed. Deep connections between the resonances in the continuous and discrete systems are revealed.
Optimization of Aerosol Penetration through Transport Lines (1992)

When aerosol particles are transported through tubing clined tubes; the optimum diameter of a straight tube systems for near-real-time monitoring purposes, there for maximum aerosol penetration; and the concept of will be losses of particles on internal surfaces of the maximum penetration, P,,,,,, between two points in transport system that will render the monitoring procspace.P,,, is the upper bound, and the ratio of the ess less accurate.Herein we consider three aspects of actual penetration, P, to P,,, gives the scope for modeling particle penetration: an analytical solution improving the transport line design to increase penetrafor the effective particle depositional velocity in in-tion.
Reductive dehalogenation of iopromide by zero-valent iron (2008)

Iodinated X-ray contrast media (ICM), as derivatives of 2, 4, 6-triiodo benzoic acid, are applied in high doses to humans and are excreted unchanged via urine within 24 h. Common as well as advanced wastewater treatment is not able to remove the iodinated compounds leading to an environmental pollution. A specific treatment of contaminated urine or hospital wastewater could minimise the emission. For that reason the deiodination of iopromide, the most commonly used ICM, was investigated using zero-valent iron. Initial experiments carried out in stirred batch reactors with an initial pH of 2 using iron powder and iopromide dissolved in ultra pure water showed that iopromide can be deiodinated by zero-valent iron. Even in contaminated urine collected in a hospital a deiodination of ICM was possible. Further experiments at different constant pH values, temperatures and stirring speeds were performed. The kinetic studies at constant pH showed that the deiodination can be described by pseudo-first order for equal iopromide and iron concentrations. In general, the reaction depends strongly on the pH, the temperature and the stirring speed. The observed rate constant K(obs) has an optimum at pH 3 and rises with increasing temperature and stirring speed.
Recovery of the Immune System With Antiretroviral Therapy (1998)

Potent antiretroviral therapy has become the standard of care for people with HIV infection, and its use has led to significant reductions in the incidence of the acquired immunodeficiency syndrome (AIDS) and in mortality from HIV infection. Although incomplete, considerable immune recovery occurs, sufficient, in most cases, to provide adequate protection against most AIDS-associated opportunistic infections.
Development of a calibration system for wafer-type temperature sensor (2020)

Wafer-type temperature sensors are widely used during semiconductor fabrication as integrated monitoring sensors for the real-time monitoring of wafer surface temperature, which affects the quality and yield of semiconductor devices. In recent years, various wafer-type temperature sensors have been developed according to the process type and temperature range for monitoring the temperature distribution. However, there is little research on the calibration system to ensure the accuracy and reliability of the developed wafer-type temperature sensor. In this study, we designed a system for the calibration of wafer-type temperature sensors. With this system, the traceability of the sensor can be guaranteed by calibrating the sensing characteristics, such as area uniformity, temperature stability, and accuracy. The conventional temperature calibration bath is calibrated by placing a wafer-type temperature sensor in a liquid-controlled system to have uniform temperature. This method is difficult to apply to the field because the wafer-type temperature sensor can be contaminated by liquids and can adversely affect semiconductor processes. For this reason, we used a heating chamber similar to chemical vapor deposition equipment for a calibration system. We evaluated the properties of the calibration system including the rising time (which means the time taken to reach the target temperature) and temperature stability according to the heat capacity. Moreover, we developed a measurement method that allows for the evaluation of the temperature of the wafer-type temperature sensor within 15 min at 150 °C. The calibration system and measurement method developed in this study are expected to improve the efficiency of semiconductor fabrication processes.
Out-of-Clinic Sympathetic Activity Is Increased in Patients With Masked Uncontrolled Hypertension (2018)

Masked uncontrolled hypertension (MUCH) is defined as controlled automated office blood pressure (BP; AOBP <135/85 mm Hg) in-clinic in patients receiving antihypertensive medication(s) but uncontrolled BP out-of-clinic by 24-hour ambulatory BP monitoring (ABPM; awake ≥135/85 mm Hg). We hypothesized that MUCH patients have greater out-of-clinic sympathetic activity compared with true controlled hypertensives. Patients being treated for hypertension were prospectively recruited after 3 or more consecutive clinic visits. All patients were evaluated by in-clinic automated office BP, plasma catecholamines, and spot-urine/plasma metanephrines. In addition, out-of-clinic 24-hour ABPM, 24-hour urinary for catecholamines and metanephrines was done. Out of 237 patients recruited, 169 patients had controlled in-clinic BP of which 156 patients had completed ABPM. Seventy-four were true controlled hypertensives, that is controlled by clinic automated office BP and by out-of-clinic ABPM. The remaining 82 were controlled by clinic automated office BP, but uncontrolled during out-of-clinic ABPM, indicative of MUCH. After exclusion of 4 patients because of inadequate or lack of 24-hour urinary collections, 72 true controlled hypertensive and 80 MUCH patients were analyzed. MUCH patients had significantly higher out-of-clinic BP variability and lower heart rate variability compared with true controlled hypertensives, as well as higher levels of out-of-clinic urinary catecholamines and metanephrines levels consistent with higher out-of-clinic sympathetic activity. In contrast, there was no difference in in-clinic plasma catecholamines and spot-urine/plasma levels of metanephrines between the 2 groups, consistent with similar levels of sympathetic activity while in clinic. MUCH patients have evidence of heightened out-of-clinic sympathetic activity compared with true controlled hypertensives, which may contribute to the development of MUCH.
SyMon: Defending large structured P2P systems against Sybil attack (2009)

Sybil attack is one of the most challenging problems that plague current decentralized Peer-to-Peer systems. In Sybil attack, a single malicious user creates multiple peer identities known as sybils. These sybils are employed to target honest peers and hence subvert the system. In this paper, we propose a novel solution that enables all honest peers to protect themselves from sybils with high probability in large structured P2P systems. In our proposed sybil defense system, we associate every peer with another non-sybil peer known as SyMon. A given peer's SyMon is chosen dynamically such that the chances of both of them being sybils are very low. The chosen SyMon is entrusted with the responsibility of moderating the transactions involving the given peer and hence makes it almost impossible for sybils to compromise the system. We show the effectiveness of our proposed system in defending against Sybil attack both analytically and experimentally.
Pretreatment with magnesium sulfate attenuates white matter damage by preventing cell death of developing oligodendrocytes (2018)

Pretreatment with MgSO<sub>4</sub> attenuates white matter damage by preventing cell death of pre-OL.
Extending spin coherence times of diamond qubits by high-temperature annealing (2013)

Spins of negatively charged nitrogen-vacancy (NV${}^{\ensuremath{-}}$) defects in diamond are among the most promising candidates for solid-state qubits. The fabrication of quantum devices containing these spin-carrying defects requires position-controlled introduction of NV${}^{\ensuremath{-}}$ defects having excellent properties such as spectral stability, a long spin coherence time, and a stable negative charge state. Nitrogen ion implantation and annealing enable the positioning of NV${}^{\ensuremath{-}}$ spin qubits with high precision, but to date, the coherence times of qubits produced this way are short, presumably because of the presence of residual radiation damage. In the present work, we demonstrate that a high-temperature annealing at 1000 ${}^{\ensuremath{\circ}}$C allows 2 ms coherence times to be achieved at room temperature. These results were obtained for implantation-produced NV${}^{\ensuremath{-}}$ defects in a high-purity, 99.99% ${}^{12}$C-enriched single crystal chemical vapor deposited diamond. We discuss these long coherence times in the context of the thermal behavior of residual defect spins.
Ultrastructural Characterization of Yellow Shoulder Disorder in a Uniform Ripening Tomato Genotype (2000)

Yellow shoulder disorder (YSD) is characterized by sectors of yellow or green tissue under the peel of uniform ripening tomato ( Lycopersicon esculentum Mill.) fruit. Tissues excised from sectors of fruit expressing YSD, from adjacent red sectors, and from mature green fruit were used to compare the ultrastructural alterations in cells and tissue affected by YSD and to determine whether the disorder is caused by delayed fruit maturation or by aberrant development. Cells from YSD sectors were smaller than those from both adjacent red-ripe tissue and mature green fruit. The smaller cells from the YSD sectors were at a different developmental stage than cells of the adjacent red-ripe tissue. Chromoplasts in red-ripe tissue were more advanced in development than those in YSD sectors or mature green fruit. Using the transition from chloroplast to chromoplast and the degradation of the middle lamella between adjacent cells as developmental markers, the maturity of tissue from YSD sectors appeared to be equal or greater than that of tissue from mature green fruit. However, cell enlargement, which takes place early in fruit development, was retarded in YSD sectors. Therefore, the ultrastructural features of YSD are not compatible with a delayed ripening model for this blotchy ripening disorder. These observations provide a basis for comparing YSD in uniformly ripening tomatoes with other blotchy ripening disorders.
The txtAB genes of the plant pathogen Streptomyces acidiscabies encode a peptide synthetase required for phytotoxin thaxtomin A production and pathogenicity (2000)

Four Streptomyces species have been described as the causal agents of scab disease, which affects economically important root and tuber crops worldwide. These species produce a family of cyclic dipeptides, the thaxtomins, which alone mimic disease symptomatology. Structural considerations suggest that thaxtomins are synthesized non-ribosomally. Degenerate oligonucleotide primers were used to amplify conserved portions of the acyladenylation module of peptide synthetase genes from genomic DNA of representatives of the four species. Pairwise Southern hybridizations identified a peptide synthetase acyladenylation module conserved among three species. The complete nucleotide sequences of two peptide synthetase genes (txtAB) were determined from S. acidiscabies 84.104 cosmid library clones. The organization of the deduced TxtA and TxtB peptide synthetase catalytic domains is consistent with the formation of N-methylated cyclic dipeptides such as thaxtomins. Based on high-performance liquid chromatography (HPLC) analysis, thaxtomin A production was abolished in txtA gene disruption mutants. Although the growth and morphological characteristics of the mutants were identical to those of the parent strain, txtA mutants were avirulent on potato tubers. Moreover, introduction of the thaxtomin synthetase cosmid into a txtA mutant restored both pathogenicity and thaxtomin A production, demonstrating a critical role for thaxtomins in pathogenesis.
Poly[2-methoxy-5-(2';-ethylhexyloxy)-(p-phenylenevinylene)] (MEH-PPV) synthesized via a modified Gilch method and the electrical conductivities of MEH-PPV/MCMB films (2011)

Poly[2-methoxy-5-(2'-ethylhexyloxy)-(p-phenylenevinylene)] (MEH-PPV) was obtained via the modified Gilch route. The expected polymer was obtained in an overall yield of 19.5%. The structures of all synthesized intermediates and MEH-PPV fully complied with their respective spectroscopic data using <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sup> H and <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">13</sup> C nuclear magnetic resonance (NMR) and Fourier transform infrared (FTIR) spectroscopies. Thermal properties of the polymer was studied using simultaneous thermogravimetry and differential scanning calorimetry (TGA/DSC) and morphologies by transmission electron microscopy (TEM). The glass transition temperature, Tg, of MEH-PPV was obtained at 85°C. TEM results showed that the material was amorphous. Results showed that pure MEH-PPV exhibited high impedance at room temperature but the impedance increases in the MEH-PPV/MCMB composite. The MEH-PPV/MCMB composite film shows an increase in conductivity of the order of 2. The enhancement of conductivity of MEH-PPV by the addition of MCMB was attributed to the change in morphology of the film and contribution of electrons by carbon in the polymer matrix.