gebhart/patrepeval huggingface dataset:
Application of Micro-thermal Analysis for Metal, Oxide, and Non-oxide Thin Film Materials (2009)

In this paper, we present the use of the micro‐thermal analyzer (TA Instruments model μTA‐2990) to detect lithographically‐defined surface and sub‐surface metal and dielectric features in silica and chalcogenide glass films. The imaging resolution of the technique was determined to be ±1 μm laterally for surface features, and up to 1μm for features located below the surface. We demonstrate that this instrument is also an effective technique for the detection of Au, Ag, and Cu nanoparticles within sol‐gel derived silica films. Lastly, we show that the micro‐thermal analyzer can also be used to measure thermal properties of bulk and film glassy materials, including thermal conductivity and probe penetration temperature.
Moessbauer-Zeeman spectra of some octaethylporphyrinato- and tetraphenylporphinatoiron(III) complexes (1978)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMoessbauer-Zeeman spectra of some octaethylporphyrinato- and tetraphenylporphinatoiron(III) complexesDavid H. Dolphin, John R. Sams, Tsang Bik Tsin, and Kit L. WongCite this: J. Am. Chem. Soc. 1978, 100, 6, 1711–1718Publication Date (Print):March 1, 1978Publication History Published online1 May 2002Published inissue 1 March 1978https://pubs.acs.org/doi/10.1021/ja00474a011https://doi.org/10.1021/ja00474a011research-articleACS PublicationsRequest reuse permissionsArticle Views188Altmetric-Citations32LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Photooxidation of Organic Chemicals Catalyzed by Nanoscale MoS2 (1998)

We describe experiments that explore the use of nanosize MoS2 semiconductors for catalyzing the photooxidation of an organic chemical, phenol. The band gap of nanoscale MoS2 can be tuned across the visible spectrum and we show that d = 4.5 nm MoS2 which has an absorbance edge near 550 nm photooxidizes phenol using only visible light (>450 nm) while smaller band gap d = 8−10 nm MoS2 or wide band gap Degussa P-25 TiO2 do not. The possibility of increasing the rate of photooxidation of phenol by deposition of nanoclusters of MoS2 on bulk semiconductor powders is investigated. It is shown that small amounts (<5 wt %) of nanoscale MoS2 deposited onto TiO2 can lead to significant (∼2-fold) enhancements of phenol destruction rates compared to TiO2 by itself.
Extraordinary optical transmission through nano-apertures in metallic surfaces: Influence of the aperture shape (2005)

Keywords: Nanophotonics, Plasmonics Reference EPFL-CONF-175026 Record created on 2012-02-21, modified on 2017-05-10
Pilot study of safety and efficacy of topical liposomal amphotericin B for cutaneous leishmaniasis caused by Leishmania major in Islamic Republic of Iran (2022)

Lip-AmB 0.4% alone or in combination with national standard treatment is safe with high-efficacy rate and warrants further investigation during phase 3 clinical trials.
Supplemental Figure 1 from First-in-Human Dose Study of the Novel Transforming Growth Factor-β Receptor I Kinase Inhibitor LY2157299 Monohydrate in Patients with Advanced Cancer and Glioma (2023)

&lt;p&gt;Supplemental Figure 1. Platelet recovery after lomustine administration was not diminished by giving LY2157299 during the recovery period suggesting no bone marrow toxicity.&lt;/p&gt;
Data from Modulation of BCL-2 in Both T Cells and Tumor Cells to Enhance Chimeric Antigen Receptor T-cell Immunotherapy against Cancer (2023)

&lt;div&gt;Abstract&lt;p&gt;Chimeric antigen receptor T-cell (CART) immunotherapy led to unprecedented responses in patients with refractory/relapsed B-cell non-Hodgkin lymphoma (NHL); nevertheless, two thirds of patients experience treatment failure. Resistance to apoptosis is a key feature of cancer cells, and it is associated with treatment failure. In 87 patients with NHL treated with anti-CD19 CART, we found that chromosomal alteration of B-cell lymphoma 2 (BCL-2), a critical antiapoptotic regulator, in lymphoma cells was associated with reduced survival. Therefore, we combined CART19 with the FDA-approved BCL-2 inhibitor venetoclax and demonstrated &lt;i&gt;in vivo&lt;/i&gt; synergy in venetoclax-sensitive NHL. However, higher venetoclax doses needed for venetoclax-resistant lymphomas resulted in CART toxicity. To overcome this limitation, we developed venetoclax-resistant CART by overexpressing mutated BCL-2(F104L), which is not recognized by venetoclax. Notably, BCL-2(F104L)-CART19 synergized with venetoclax in multiple lymphoma xenograft models. Furthermore, we uncovered that BCL-2 overexpression in T cells intrinsically enhanced CART antitumor activity in preclinical models and in patients by prolonging CART persistence.&lt;/p&gt;Significance:&lt;p&gt;This study highlights the role of BCL-2 in resistance to CART immunotherapy for cancer and introduces a novel concept for combination therapies—the engineering of CART cells to make them resistant to proapoptotic small molecules, thereby enhancing the therapeutic index of these combination therapies.&lt;/p&gt;&lt;p&gt;&lt;i&gt;&lt;a href="https://aacrjournals.org/cancerdiscovery/article/doi/10.1158/2159-8290.CD-12-10-ITI" target="_blank"&gt;This article is highlighted in the In This Issue feature, p. 2221&lt;/a&gt;&lt;/i&gt;&lt;/p&gt;&lt;/div&gt;
The Cover (1991)

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Tandem 1,2-sulfur migration and (aza)-Diels–Alder reaction of β-thio-α-diazoimines: rhodium catalyzed synthesis of (fused)-polyhydropyridines, and cyclohexenes (2015)

Rhodium catalyzed synthesis of substituted tetrahydropyridines was accomplished from readily accessible thio-tethered <i>N</i>-sulfonyl-1,2,3-triazoles. The reaction involves tandem rhodium catalyzed 1,2-sulfur migration in β-thio-α-diazoimines, generated from thio-tethered <i>N</i>-sulfonyl-1,2,3-triazoles, to thio-substituted 1-azadiene and subsequent self aza-Diels-Alder reaction. Interestingly, the methodology was effectively extended to the synthesis of fused tetrahydropyridines, dihydropyridines and cyclohexenes through the <i>in situ</i> trapping of the intermediate, 1-azadiene, with various dienophiles such as enol ether, enamine, ketene <i>S</i>,<i>S</i>-acetal, alkyne, alkene and diene. Furthermore, the direct conversion of propargyl sulfides to (fused)-tetrahydropyridines was also achieved through the successful integration of copper and rhodium catalysts in one-pot.
Preoperative Paclitaxel and Concurrent Rapid-Fractionation Radiation for Resectable Pancreatic Adenocarcinoma: Toxicities, Histologic Response Rates, and Event-Free Outcome (2002)

Preoperative paclitaxel-based concurrent chemoradiation is feasible. The toxicity of this regimen seems greater than that with fluorouracil. The histologic responses and survival are similar, suggesting no advantages to paclitaxel-based preoperative treatment.
A fervent plea for second-order toxicology (2014)

Environmental Toxicology and ChemistryVolume 33, Issue 3 p. 479-480 Letter to the Editor A fervent plea for second-order toxicology Lawrence V. Tannenbaum, Corresponding Author Lawrence V. Tannenbaum US Army Institute of Public Health, Public Health Command, Aberdeen Proving Ground, MarylandAddress correspondence to [email protected].Search for more papers by this author Lawrence V. Tannenbaum, Corresponding Author Lawrence V. Tannenbaum US Army Institute of Public Health, Public Health Command, Aberdeen Proving Ground, MarylandAddress correspondence to [email protected].Search for more papers by this author First published: 14 February 2014 https://doi.org/10.1002/etc.2463Citations: 3Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article.Citing Literature Volume33, Issue3March 2014Pages 479-480 RelatedInformation
Suivi en ligne et optimisation de la capacité d'épuration d'un digesteur anaérobie de type lit fluidisé par la méthode des impulsions (1996)

*INRA, Centre de Montpellier (FRA) Diffusion du document : INRA, Centre de Montpellier (FRA)
A 2 GHz 12-bit digital-to-analog converter for direct digital synthesis applications (2002)

A 2 GHz 12-bit digital-to-analog converter (DAC) designed for use in a Direct Digital Synthesizer was demonstrated with spurious performance exceeding -60 dBc when synthesizing 1/8th of a 1 GHz clock. This exceeds the best documented results of which we are aware by more than 15 dB at this clock rate and fractional frequency. When synthesizing near 1/3rd the clock rate the carrier-adjacent spurious performance exceeds -58 dBc at a 1 GHz clock rate, exceeding the 500 MHz clock rate performance of other DACs we have evaluated by 5-10 dB. Although designed to operate well above 2 GHz, state-of-the-art test equipment limited full characterization of the device to a 1 GHz clock rate at the time of evaluation. Unlike that observed with other DACs, nearly constant measured performance versus clock rate up to 1 GHz promises sustained performance at higher clock rates. The 12 bit DAC architecture consists of the 3 most significant bits driving 7 equally weighted current segments while the remaining 9 bits drive identical current segments combined through a binary R2R ladder. This architecture represents the best tradeoff between performance considerations and circuit complexity. The primary focus on this first design iteration was on achieving good spurious performance with less emphasis on power dissipation and on providing key information for a subsequent design optimization. The DAC was fabricated using an integrated circuit process developed at Hughes Research Laboratories and consists of 1200 AlInAs/GaInAs HBTs lattice matched to an InP substrate. The smallest InP-based HBTs utilized emitters having 2/spl times/2 sq. micron emitters with Ft=75 GHz and Fmax=85 GHz. The high speed DAC dissipated 2.8 W.
Material properties of bulk InGaAs and InAlAs/InGaAs heterostructures grown on (111)B and (111)B misoriented by 1° towards 〈211〉 InP substrates (2000)

High-quality bulk InGaAs and InAlAs/InGaAs heterostructures have been grown on InP substrates with different orientation using molecular-beam epitaxy. It was found that the electrical and structural properties were strongly dependent on growth temperature and substrate misorientation. The electrical and structural properties of the film were investigated by high-resolution x-ray diffraction, Nomarski microscope, and Hall measurements. Full-width at half-maximum of 380 arcsec for bulk InGaAs on (111)B and 70 arcsec on (111)B misoriented by 1° towards 〈211〉 InP substrates were measured by x-ray diffraction. The room temperature electron Hall mobility for bulk InGaAs of 5100 cm2/V s, doped with Si concentration at the mid-1017/cm3, and two-dimensional electron gas mobility of 11 200 cm2/V s, and sheet density of 3.0×1012/cm2 for InAlAs/InGaAs heterostructures on (111)B misoriented by 1° towards 〈211〉 InP substrates were achieved.
Cytomegalovirus Viremia and Relapse after Haploidentical Hematopoietic Cell Transplantation (2016)

Recent studies have demonstrated reduced risk of relapse in recipients of HCT who develop CMV viremia following transplant. There is a paucity of data on CMV viremia and transplant outcomes in patients after T-cell replete haplo-HCT on Hopkins post transplant cyclophosphamide (PT-Cy) platform. This is a retrospective cohort study of all T cell replete haplo-HCT recipients at our institution from 2009 to 2015. Analyses were performed on the overall cohort and on two subgroups (AML alone, and AML+MDS). The primary outcome was cumulative incidence of disease relapse, with CMV viremia (defined as a positive CMV DNA PCR measurement), treated as a time-dependent covariate and non-relapse mortality (NRM) treated as a competing event. Secondary endpoints included non-relapse related mortality (NRM, with relapse treated as competing event), overall survival (OS), and graft versus host disease (GVHD). Other potential covariates were analyzed by univariate Cox regression, and if statistically significant, included in multivariate Cox model along with CMV viremia. 103 patients were analyzed. Baseline characteristics are in Table 1. 71 patients (69%) were at risk for CMV based on donor and/or recipient seropositivity. Median follow-up was 218 days. CMV viremia was observed in 55 patients (53.4% overall, 77% at risk), with a median time to viral detection of 24 days (SD = 12). The univariate analysis demonstrated that CMV viremia was not significantly associated with a difference in relapse (HR = 0.88, 95% CI [0.39-1.95], p = 0.75) NRM (HR = 0.54 [0.23-1.24], p = 0.15), or OS (HR = 0.72 [0.40-1.30], p = 0.27) (Figure 1). Subgroup analysis yielded non-significant results. There was also no significant difference in GVHD with CMV viremia in these patients. CMV viremia is common and occurs relatively early in peripheral blood T cell replete haplo-HCT. However we did not find a significant correlation between CMV viremia and decreased incidence of relapse or a change in overall survival in recipients of haplo-HCT.Table 1Patient Characteristics.NNo CMVCMVP4855Age - No. (%)0.14<6040 (83.3)39 (70.9)Sex0.11Male31 (64.6)27 (49.1)Race0.007White43 (89.6)37 (67.3)Other5 (10.4)18 (32.7)Donor-patient CMV status<0.001D-/R-30 (62.5)2 (3.6)D-/R+4 (8.3)22 (40.0)D+/R-10 (20.8)4 (7.3)D+/R+3 (6.25)25 (45.5)Unknown1 (2.1)2 (3.6)Diagnosis0.46AML33 (68.8)36 (65.5)MDS6 (12.5)4 (7.3)Other9 (18.8)15 (27.3)Disease status0.88Active25 (52.1)29 (52.7)Remission22 (45.8)24 (43.6)N/A1 (2.1)2 (3.6)Prior Transplant0.004Yes19 (39.6)8 (14.6)Conditioning regimen0.12MA21 (43.8)16 (29.1)Immune prophylaxis0.54Tacro/MMF45 (93.8)53 (93.4Other3 (6.2)2 (6.6)aGVHD0.87Grades 0-I33 (68.75)37 (67.27)Grades II-IV15 (31.25)18 (32.73)cGVHD0.92Yes17 (35.42)20 (36.36) Open table in a new tab
HIV‐1‐specific cell‐mediated immune responses induced by DNA vaccination were enhanced by mannan‐coated liposomes and inhibited by anti‐interferon‐γ antibody (1997)

The adjuvant effect of mannan-coated liposomes on human immunodeficiency virus type-1 (HIV-1) DNA vaccine and the mechanism of this enhancement were studied. Coating of cationic liposomes with mannan significantly enhanced the ability of this vaccine to induce an HIV-specific delayed-type hypersensitivity (DTH) response. HIV-specific cytotoxic T-cell (CTL) activity elicited by DNA vaccination was also significantly enhanced with the mannan-liposome cocktail. This mannan-liposome-mediated activity was greatly inhibited by in vivo injection of anti-interferon (IFN)-gamma antibody, which suggests that IFN-gamma plays an important role in this HIV-specific immune response. The results of both isotype-specific antibody and cytokine analysis revealed that mannan-liposome-mediated DNA vaccination enhances Th1-mediated immunity.
Effect of Flow Pulsatility and Wall Compliance on the Energy Loss in the Total Cavopulmonary Connection (2013)

Single Ventricle Heart Defects (SVHD) are present in 2 per 1000 live births in the US. SVHD are characterized by cyanotic mixing between the de-oxygenated blood from the systemic circulation return and the oxygenated blood from the pulmonary arteries. In the current practice, surgical interventions on SVHD patients commonly result in the total cavopulmonary connection (TCPC) [1]. In this configuration the systemic venous returns (inferior vena cava, IVC, and superior vena cava, SVC) are directly routed to the right and left pulmonary arteries (RPA and LPA), bypassing the right heart. The resulting anatomy has complex and unsteady hemodynamics characterized by flow mixing and flow separation. Pulsation of the inlet venous flow during a cardiac cycle and wall motion may result in complex and unsteady flow patterns in the TCPC. Although vessel wall motion and different degrees of pulsatility have been observed in vivo, non-pulsatile (time-averaged) flow boundary conditions and rigid walls have traditionally been assumed in estimating the TCPC hemodynamic parameters (such as energy loss). Recent studies have shown that these assumptions may result in significant inaccuracies in modeling TCPC hemodynamics [2, 3].
Multiple Carotid Arterial Injuries in the Skull Base; Angiographic Pitfalls in Diagnosis, and Principle of Endovascular Embolization (2007)

Purpose: Simultaneous occurrences of multiple carotid injuries (CAIs) in the skull base following head trauma are usually fatal and are rarely referred for endovascular treatment. The purpose of this study was to describe the potential angiographic pitfalls in diagnoses of multiple CAIs in the skull base and to report our experiences of endovascular management of 15 patients with multiple CAIs.
Novel Reversible Multiplier Architecture Using Reversible TSG Gate (2006)

In the recent years, reversible logic has emerged as a promising technology having its applications in low power CMOS, quantum computing, nanotechnology, and optical computing. The classical set of gates such as AND, OR, and EXOR are not reversible. Recently a 4 * 4 reversible gate called “TSG” is proposed. The most significant aspect of the proposed gate is that it can work singly as a reversible full adder, that is reversible full adder can now be implemented with a single gate only. This paper proposes a NXN reversible multiplier using TSG gate. It is based on two concepts. The partial products can be generated in parallel with a delay of d using Fredkin gates and thereafter the addition can be reduced to log2N steps by using reversible parallel adder designed from TSG gates. A 4x4 architecture of the proposed reversible multiplier is also designed. It is demonstrated that the proposed multiplier architecture using the TSG gate is much better and optimized, compared to its existing counterparts in literature; in terms of number of reversible gates and garbage outputs. Thus, this paper provides the initial threshold to building of more complex system which can execute more complicated operations using reversible logic.
LETTERS TO THE EDITOR (1973)

SULFONIC ACID It has been established that myosin A ATPase (EC 3. 6. 1. 3. ATP phosphohydrolase, rabbit muscle) contains one fast reactive sulfhydryl group per subunit.1,2) The most remarkable change in the catalytic properties brought about by the chemical modification of this sulfhydryl group, named S1, with N-ethylmaleimide
Letter to the Glyco-Forum: Galections: conservation of functionally and structurally relevant amino acid residues defines two types of carbohydrate recognition domains (1994)

Journal Article Letter to the Glyco-Forum: Galections: conservation of functionally and structurally relevant amino acid residues defines two types of carbohydrate recognition domains Get access Hafiz Ahmed, Hafiz Ahmed Center of Marine Biotechnology, University of Maryland Biotechnology Institute600 E. Lombard Street, Baltimore, MD 21202, USA. Search for other works by this author on: Oxford Academic PubMed Google Scholar Gerardo R. Vasta, Gerardo R. Vasta Center of Marine Biotechnology, University of Maryland Biotechnology Institute600 E. Lombard Street, Baltimore, MD 21202, USA. Search for other works by this author on: Oxford Academic PubMed Google Scholar B. M. ANSELL B. M. ANSELL Center of Marine Biotechnology, University of Maryland Biotechnology Institute600 E. Lombard Street, Baltimore, MD 21202, USA. Search for other works by this author on: Oxford Academic PubMed Google Scholar Glycobiology, Volume 4, Issue 5, October 1994, Pages 545–548, https://doi.org/10.1093/glycob/4.5.545 Published: 01 October 1994
La teneur en lysine totale et disponible du lait, des fromages et des produits de boulangerie ayant subi un traitement industriel (1972)

Des expenences anterieures [1] ont montre que le dosage de la lysine totale nous renseigne mal sur la valeur des aliments, si ces aliments ont subi un traitement thermique au cours de leur preparation. Ce dosage ordinaire, selon la methode de Spakmann, Stein et Moore [2] est purement quantitatif. Applique aux produits alimentaires avant et apres traitement industriel, il permet seulement d'apprecier la destruction de lysine. Or, les traitements industriels peuvent non seulement detruire une partie de la lysine, mais egalement en rendre une autre partie inassimilable par suite du blocage du groupement E-NH2de la lysine (reaction de Maillard). La methode au fluorodinitrobenzene de Carpenter permet de tenir compte a la fois, de la destruction et du blocage de la lysine. (Nous avons modifie la methode de Carpenter en substituant au dosage colorimetrique de la dinitrophenyllysine, une separation de ce corps sur colonne d'echangeurs d'ions suivie d'un dosage photometrique apres reaction avec la ninhydrine). Des essais de croissance sur rats et poulets [1] ont montre que la valeur alimentaire d'une ration chauffee n'est pas affectee si l'addition de lysine de synthese compense exactement la perte de lysine disponible due au chauffage. Si cette addition de lysine de synthese Ile fait que compenser la destruction de lysine, elle est insuffisante pour restituer a la ration chauffee, sa valeur alimentaire primitive.
Optimal Transmission of Light through Disordered Materials (2009)

Disordered photonic materials scatter and blur incident light. By controlling the incident wavefront, we show it is possible to focus light through and even inside such materials. The focusing resolution can be surprisingly high.