gebhart/patrepeval huggingface dataset:
The Preparation of Acetylenic Carbinols1 (1938)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Preparation of Acetylenic Carbinols1Kenneth N. Campbell, Barbara K. Campbell, and Lawrence T. EbyCite this: J. Am. Chem. Soc. 1938, 60, 12, 2882–2884Publication Date (Print):December 1, 1938Publication History Published online1 May 2002Published inissue 1 December 1938https://pubs.acs.org/doi/10.1021/ja01279a014https://doi.org/10.1021/ja01279a014research-articleACS PublicationsRequest reuse permissionsArticle Views381Altmetric-Citations36LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Processing results of polymer liquid chromatography using multi-agent system (2005)

In this contribution we apply the multi-agent system approach to treat selected SEC (Size-excluded chromatography) and enthalpy assisted SEC calibration curves. Individual agents represent approximation of experimentally measured calibration curves by different types of empirical functions. Decision agent detects the best model of simulation. The genetic programming is suggested for the approximation of calibration curves by arbitrary function.
Louder Than Words: Dance/Movement Therapy Groups with Men on an Inpatient Forensic Unit (2010)

Dance/movement therapy groups in an acute forensic setting offer patients the opportunity to express themselves through use of the body and the creative process. This paper introduces the reader to the climate and conditions of an inpatient forensic unit that treats acutely mentally ill men who are incarcerated, and examines how these aspects affect the therapeutic group space. Material from sessions is used to explore the ways in which theories of group dynamics (safety, stages of group development, boundaries, and group norms) are modified to accommodate the forensic setting.
Unique Strain of Rickettsia parkeri Associated with the Hard Tick Dermacentor parumapertus Neumann in the Western United States (2017)

In 1953, investigators at the Rocky Mountain Laboratories in Hamilton, MT, described the isolation of a spotted fever group <i>Rickettsia</i> (SFGR) species from <i>Dermacentor parumapertus</i> ticks collected from black-tailed jackrabbits (<i>Lepus californicus</i>) in northern Nevada. Several decades later, investigators characterized this SFGR (designated the parumapertus agent) by using mouse serotyping methods and determined that it represented a distinct rickettsial serotype closely related to <i>Rickettsia parkeri</i>; nonetheless, the parumapertus agent was not further characterized or studied. To our knowledge, no isolates of the parumapertus agent remain in any rickettsial culture collection, which precludes contemporary phylogenetic placement of this enigmatic SFGR. To rediscover the parumapertus agent, adult-stage <i>D. parumapertus</i> ticks were collected from black-tailed jackrabbits shot or encountered as roadkills in Arizona, Utah, or Texas from 2011 to 2016. A total of 339 ticks were collected and evaluated for infection with <i>Rickettsia</i> species. Of 112 <i>D. parumapertus</i> ticks collected in south Texas, 16 (14.3%) contained partial <i>ompA</i> sequences with the closest identity (99.6%) to <i>Rickettsia</i> sp. strain Atlantic rainforest Aa46, an SFGR that is closely related or identical to an SFGR species that causes a mild rickettsiosis in several states of Brazil. A pure isolate, designated strain Black Gap, was cultivated in Vero E6 cells, and sequence analysis of the <i>rrs</i>, <i>gltA</i>, <i>sca0</i>, <i>sca5</i>, and <i>sca4</i> genes also revealed the closest genetic identity to <i>Rickettsia</i> sp. Atlantic rainforest Aa46. Phylogenetic analysis of the five concatenated rickettsial genes place <i>Rickettsia</i> sp. strain Black Gap and <i>Rickettsia</i> sp. Atlantic rainforest Aa46 with <i>R. parkeri</i> in a distinct and well-supported clade.<b>IMPORTANCE</b> We suggest that <i>Rickettsia</i> sp. Black Gap and <i>Rickettsia</i> sp. Atlantic rainforest Aa46 represent nearly identical strains of <i>R. parkeri</i> and that <i>Rickettsia</i> sp. Black Gap or a very similar strain of <i>R. parkeri</i> represents the parumapertus agent. The close genetic relatedness among these taxa, as well as the response of guinea pigs infected with the Black Gap strain, suggests that <i>R. parkeri</i> Black Gap could cause disease in humans. The identification of this organism could also account, at least in part, for the remarkable differences in severity ascribed to Rocky Mountain spotted fever (RMSF) among various regions of the American West during the early 20th century. We suggest that the wide variation in case fatality rates attributed to RMSF could have occurred by the inadvertent inclusion of cases of milder disease caused by <i>R. parkeri</i> Black Gap.
Learning developmental biology has priority in the life sciences curriculum in Singapore (2003)

Singapore has embraced the life sciences as an important discipline to be emphasized in schools and universities. This is part of the nation's strategic move towards a knowledge-based economy, with the life sciences poised as a new engine for economic growth. In the life sciences, the area of developmental biology is of prime interest, since it is not just intriguing for students to know how a single cell can give rise to a complex, coordinated, functional life that is multicellular and multifaceted, but more importantly, there is much in developmental biology that can have biomedical implications. At different levels in the Singapore educational system, students are exposed to various aspects of developmental biology. The author has given many guest lectures to secondary (ages 12-16) and high school (ages 17-18) students to enthuse them about topics such as embryo cloning and stem cell biology. At the university level, some selected topics in developmental biology are part of a broader course which caters for students not majoring in the life sciences, so that they will learn to comprehend how development takes place and the significance of the knowledge and impacts of the technologies derived in the field. For students majoring in the life sciences, the subject is taught progressively in years two and three, so that students will gain specialist knowledge in developmental biology. As they learn, students are exposed to concepts, principles and mechanisms that underlie development. Different model organisms are studied to demonstrate the rapid advances in this field and to show the interconnectivity of developmental themes among living things. The course inevitably touches on life and death matters, and the social and ethical implications of recent technologies which enable scientists to manipulate life are discussed accordingly, either in class, in a discussion forum, or through essay writing.
Sex Differences in Biomechanics Associated with Knee Osteoarthritis (2009)

Osteoarthritis of the knee is seen more frequently in females than males. However, few studies have examined the interplay of gender, gait mechanics, pain, and disability in persons with osteoarthritis. This study examines the influence of anthropometrics, radiographic disease severity, pain, and disability on gender differences in gait mechanics in patients with knee osteoarthritis. Gait mechanics for 26 men and 30 women were collected using 3-D kinematics and kinetics. Women had a significantly lower knee adduction moment than men and a significantly higher stride frequency. Within female subjects, variations in gait mechanics were primarily explained by weight, BMI, pain, and disability. In males, variations in gait mechanics were primarily explained by age and disability.
Adsorptive Removal of Tetracycline on Graphene Oxide Loaded with Titanium Dioxide Composites and Photocatalytic Regeneration of the Adsorbents (2018)

Graphene oxide loaded with titanium dioxide composites (GO-TiO2) was successfully prepared by hydrolysis of titanium tetrachloride in the presence of an aqueous dispersion of graphene oxide, and characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray photoelectron spectroscopy (XPS), transmission electron microscope (TEM), and X-ray diffraction (XRD). Characterized results exhibited that TiO2 was successfully loaded on the surface of GO. Adsorptive removal of tetracycline (TC) by GO-TiO2 and photocatalytic regeneration of adsorbent was investigated. Adsorption isotherms of TC onto GO-TiO2 proved that the adsorption process was multilayered, and the adsorption capacity of GO-TiO2 for aqueous TC in the tested range was 99.46, 117.98, and 133.05 mg/g at 15, 25, and 35 °C, respectively. TC adsorption by GO-TiO2 followed the pseudo-second-order kinetic model. TC adsorption by GO-TiO2 was favored at lower pH and decreased with an increase of solution pH. Additionally, Ca2+ had a more powerful inhibiting effect on TC adsorption by GO-TiO2 than K+ and Na+. The regeneration experiment demonstrated that the TC saturated GO-TiO2 could be easily recovered and regenerated by the photolysis under UV irradiation and the regenerated GO-TiO2 still showed high adsorption affinity for TC in solution.
Antibiotic efflux mechanisms (1999)

Bacterial genomes sequenced to date almost invariably contain genes apparently coding for multidrug efflux pumps, and the yeast genome contains more than 30 putative multidrug efflux genes. Thus it is not surprising that multidrug efflux is a major cause of intrinsic drug resistance in many microorganisms, and plays an even more prominent role in organisms with a low-permeability cell wall, such as Gram negative bacteria in general and Pseudomonas aeruginosa in particular, as well as Mycobacterium species. Furthermore, overproduction of intrinsic pumps, or acquisition of pump genes from external sources, often results in high levels of resistance. This review discusses the classification of efflux proteins, their mechanism of action, the regulation of their expression, and the clinical significance of efflux pumps.
GPU++ : an embedded GPU development system for general-purpose computations (2007)

This thesis presents a novel system for general-purpose GPU programming. It features a seamless integration into the C++ programming language to address graphics hardware via a familiar syntax, an abstraction layer to efficiently hide the different computation frequencies, and a novel approach to relax the vector processor paradigm of the GPU. The development system enables software engineers to embed GPU-based development into their existing software process, thus, largely dissolving the differences between main and graphics processor.
Thermal analysis of a plastic helical coil heat exchanger for a domestic water storage tank (2017)

In the present study, the heat transfer coefficients of helically coiled corrugated plastic tube heat exchanger inside of the solar boiler vessel were investigated experimentally. The metal coil of the conventional solar boiler for domestic usage was replaced by a plastic tube and the results were compared with the numerical simulation and the technical documentation of the initial solar boiler. All the required parameters like inlet and outlet temperatures of tubeside and stratified temperatures, flow rate of fluids, etc. were measured using appropriate instruments. The test runs were performed for different temperatures inside the tank ranging from 30-60°C and different flow rates from which the heat transfer coefficients were calculated.
Design of Superconducting Magnet for Background Magnetic Field (2008)

For the advanced testing of High Temperature Superconducting (HTS) wire/tape and sample coils, a wide bore conduction-cooled superconducting magnet with the available warm bore of 0186 mm and a center field of 5~6 T for background magnetic field applications was designed and fabricated. The magnet is composed of four coaxial coils. All the coils were connected in series and can be powered with a single power supply. The maximum magnetic field is 5.5 T. In order to support the high stress in superconducting magnet a detailed finite element (FE) analysis with electro-plastic model has been performed. A compact cryostat with a two-stage GM cryocooler was designed and manufactured for the magnet. The detailed design of magnet system is described in this paper.
Initial electron distributions for free-electron lasers generated by injector and accelerator simulations (1987)

Early free-electron laser (FEL) development was guided by simple performance criteria based on the number of undulator periods, electron beam quality, and current. The beam quality (emittance and energy spread) was used to characterize the initial distribution of axial electron velocities along the undulator axis. While the emittance and energy spread determine the overall width of the distribution, its detailed shape is also important. As new accelerators are designed specifically for FEL applications, it becomes important to obtain distribution shape information from simulations that include the electron gun, accelerator, and beam transport in addition to the usual electron/optical interaction in the undulator. The distribution at the entrance to the undulator can be calculated from numerical simulations of the cathode emission, acceleration, and transport of an electron beam. We have modeled the beam generation, from cathode emission up to the energy of the accelerator injector, using an axisymmetric, cylindrical geometry particle simulation (DPC). This code solves the relativistic force equation with fields obtained from Maxwell's equations in the Darwin model. The DPC calculation is run repeatedly varying parameters such as accelerating stress, electrode configuration, and axial magnetic field profile until a good match is obtained for the accelerator. The beam exiting from the injector can be accelerated and transported using the transfer matrix technique with a simple model for accelerating gaps and magnets. Alternatively, acceleration and transport can be simulated with a particle code that solves for the axisymmetric evolution of a slice of an electron beam including possible emittance growth. The phase space obtained from the accelerator can be evaluated for performance using either the simple FEL integral equation method or the more complete FRED simulation code. 9 refs., 5 figs.
Combining Time-Flexible GEO Satellite Payload With Precoding: The Cluster Hopping Approach (2023)

High throughput geostationary orbit (GEO) satellite systems are characterized by a multi-beam wide coverage. However, developing efficient resource management mechanisms to meet the heterogeneous user traffic demands remains an open challenge for satellite operators. Furthermore, the spectrum shortage and the ever-increasing demands claim for more aggressive frequency reuse. In this paper, we combine the time-flexible payload capabilities known as beam hopping (BH) with precoding techniques in order to satisfy user traffic requests in areas of high demand (i.e. hot-spot areas). The proposed framework considers a flexible beam-cluster hopping where adjacent beams can be activated if needed, forming clusters with various shapes and sizes. In this context, we present three strategies to design the beam illumination patterns. First, a max-min user demand fairness satisfaction problem; second, a penalty-based optimization is considered to penalize the occurrence of adjacent beams in an attempt to avoid precoding whenever possible. Third, seeking a low-complexity design, we propose a queuing-based approach to solve the problem in a time-slot-by-time-slot basis trying to provide service to users based on the requested demands. The three methods are discussed in detail and evaluated via numerical simulations, confirming their effectiveness versus benchmark schemes and identifying the pros and cons of each proposed design.
A Stitch in Time - Autonomous Model Management via Reinforcement Learning (2018)

Concept drift - a change, either sudden or gradual, in the underlying properties of data - is one of the most prevalent challenges to maintaining high-performing learned models over time in autonomous systems. In the face of concept drift, one can hope that the old model is sufficiently representative of the new data despite the concept drift, one can discard the old data and retrain a new model with (often limited) new data, or one can use transfer learning methods to combine the old data with the new to create an updated model. Which of these three options is chosen affects not only near-term decisions, but also future needs to transfer or retrain. In this paper, we thus model response to concept drift as a sequential decision making problem and formally frame it as a Markov Decision Process. Our reinforcement learning approach to the problem shows promising results on one synthetic and two real-world datasets.
Total amount of circulating human chorionic gonadotrophin α and β subunits in first trimester trisomies 21 and 18 (1996)

The aim of this study was to evaluate the variations in the balance between total (free and combined) circulating alpha and beta subunits of human chorionic gonadotrophin (hCG) in trisomy 21 and 18. Maternal serum samples were collected at 10 and 11 weeks of gestation from 22 singleton pregnancies with trisomy 21 (n = 17) and trisomy 18 (n = 5) and 66 chromosomally normal controls, matched for gestational age. The hCG and free alpha and beta subunits circulating levels were measured using specific immunoradiometric assays and converted in a common unit system obtained using calibration of the assays with intact and thermally dissociated purified hCG preparation. In trisomy 21, the only significant difference from controls was in the free beta hCG level which was increased. In trisomy 18, intact hCG, free beta hCG as well as total alpha hCG and total beta hCG levels were significantly lower whereas the free alpha hCG level was significantly higher than in controls. The decrease in total beta hCG was more pronounced than the decrease in total alpha hCG resulting in a significant increase in the total alpha- to beta hCG subunit ratio in trisomy 18. These findings suggest some modifications in the biosynthesis and/or release rates of the hCG subunits in these trisomies.
Molecular cloning and carboxyl-propeptide analysis of human type III procollagen (1984)

Two human cDNA libraries prepared from normal fibroblast (GM3348) and rhabdomyosarcoma (CCL136) mRNAs were screened under cross hybridization conditions with a genomic fragment coding for exons 2 and 3 of the avian type III procollagen COOH-propeptide (Yamada, Y., Mudryj, M., Sullivan, M. and deCrombrugghe, B. (1983) J. Biol. Chem. 258, 2758-2761). One cDNA clone containing a 1.12 kb insert was isolated from the CCL136 library and later used to identify a GM3348 derived clone with a 2.4 kb insert. Comparison of the human and avian type III C-terminal propeptides revealed much more divergence in the first 54 amino acids following the terminal cysteine of the triple helical region than is present in the alpha 1(I) and alpha 2(I) procollagen chains of these species. Analysis of poly (A+) RNA from normal human fibroblast and tumor cell lines showed that they differed greatly in the relative amounts of alpha 1(I), alpha 2(I), and alpha 1(III) mRNAs. Furthermore, as we previously reported for the alpha 1(I) and alpha 2(I) transcripts, multiple mRNAs also hybridize to the cloned alpha 1(III) DNA.
Thermally stable narrow-bandpass filter prepared by reactive ion-assisted sputtering (2001)

Thermal stabilities of three-cavity narrow-bandpass (NB) filters with high-index half-wave spacers and 78-102 layers of Ta(2)O(5) and SiO(2) prepared by reactive ion-assisted bipolar direct-current (dc) magnetron sputtering of tantalum and silicon targets, respectively, were investigated. Pure argon and pure oxygen were used as the sputtering gas and the reactant, respectively. The oxygen gas was introduced and ionized through the ion gun and toward the unheated BK7 glass substrate. The refractive indices of single-layer Ta(2)O(5) and SiO(2) films were 2.1 and 1.45, respectively, at 1550 nm, which were comparable with those of films prepared by other ion-assisted coating techniques. The moisture-resistant properties of the films were excellent as evidenced from the water-immersion test, implying that the packing density of the films was close to that of their bulk materials. The temperature-dependant wavelength shifts of the NB filters were <3 x 10(-3) nm/ degrees C at temperatures of <75 degrees C, indicating that the temperature-induced wavelength shift of the filter was <0.15 nm when the temperatures were raised from room temperature to 75 degrees C, which was compliant with Bellcore GR-1209-CORE generic requirements of NB filters used for optical-fiber communication systems.
Photo-induced growth of DNA-capped silver nanoparticles (2012)

We report the photo-induced nucleation and growth of silver nanoparticles in aqueous solution in the presence of DNA oligomers. An organic dye (Cy5) was used as a photosensitizer to initiate the nanoparticle growth upon illumination with 647 nm light. The formation of nanoparticles and growth kinetics were observed by extinction spectroscopy, dynamic light scattering, and transmission electron microscopy. Irradiation of the precursor solutions with light at the Cy5 absorption maximum triggered the instantaneous formation of spherical particles with a metallic core ~15 nm in diameter. Remarkably, the particles feature significantly larger effective hydrodynamic diameters (35 nm) in solution, indicative of a DNA ad-layer on the nanoparticle surface. Centrifugation experiments confirmed that DNA was inseparably associated with the nanoparticles and indicated that DNA oligomers adsorb onto the nanoparticle surface during growth, playing the role of a capping agent. The introduced method is a fast and facile way to prepare DNA-capped silver nanoparticles in a single growth step.
ChemInform Abstract: Synthesis of 2‐Cyanomethylazaheterocycle Derivatives. (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.