gebhart/patrepeval huggingface dataset:
Berücksichtigung von Risikoaversion in stochastischen, dynamischen Optimierungsproblemen (2013)

Für den Erfolg in Studium und Beruf ist aktuelles und methodisches Wirtschaftswissen das A und O. Die Zeitschrift WiSt liefert dieses Wissen Monat für Monat. Hochaktuelle Wirtschaftsthemen werden vor dem Hintergrund der volks- und betriebswirtschaftlichen Modelle erörtert und diskutiert. So bleiben Sie up-to-date, kennen die brisanten Details und durchschauen schnell komplexe Wirtschaftsstrukturen.
Modeling, analysis, and implementation of real time network controlled parallel multi-inverter systems (2012)

In this paper, a real time network controlled multi-inverter parallel system by using a newly published network protocol Ethercat is discussed. Compared to the traditional communication method, the advantage of real time networked control is gained from providing a high-quality synchronization signal, high speed communication rate (100Mbps), real-time central control, and signal immunity to analogue disturbance induced by long distance communication. Delay effect introduced by networked control is investigated in detail and controller design process is presented. Besides, a generalized model of network controlled multi-inverter parallel system is presented to facilitate current sharing controller design. The experiments validate that real time networked control has a promising future in implementing multi-inverter parallel system in either a multi-UPS system or a microgrid.
Lighting a Fire: Can We Harness Pyroptosis to Ignite Antitumor Immunity? (2021)

The impressive success of current cancer immunotherapy in some patients but lack of effectiveness in most patients suggests that additional strategies to promote antitumor immunity are needed. How cancer cells die, whether spontaneously or in response to therapeutic intervention, has a profound effect on the type of immune response mobilized. Here, we review research that highlights a previously unappreciated role of gasdermin-mediated inflammatory death (pyroptosis) to promote antitumor immunity and identifies gasdermin E as a tumor suppressor. Immune elimination of tumor cells by natural killer cells and cytotoxic T lymphocytes, which is the final key event in antitumor immunity, was previously thought to be noninflammatory. The research shows that gasdermin expression in tumor cells converts immune cell-mediated killing to inflammatory pyroptosis when cell death-inducing granzymes directly cleave and activate gasdermins. Granzyme B cleaves gasdermin E, and granzyme A cleaves gasdermin B. The data suggest the potential to harness pyroptosis in the tumor to ignite an effective immune response to immunologically cold tumors. Gasdermin expression also augments toxicity of cancer therapy-gasdermin E expression by B-cell leukemias and lymphomas is a root cause of chimeric antigen receptor (CAR) T-cell cytokine storm, and its expression in normal tissues promotes the toxicity of chemotherapeutic drugs. Even though our knowledge about the role of pyroptosis in cancer is growing, there is still a lot to learn-what activates it, how it is regulated, when it is beneficial, and how it can be harnessed therapeutically to improve cancer immunotherapy or reduce therapy-related toxicity.
Asymmetric Synthesis of the Polyol Subunit of the Macrolide Antibiotic, Ossamycin: A Unique Approach Utilizing Stereochemical Specificity (2006)

Abstract An asymmetric synthesis of the C1–C16 polyol subunit 2 of the macrolide antibiotic ossamycin (1) has been achieved through stepwise carbon-chain elongation reaction from d-glucose, based on a chiral pool approach. An outstanding point of this strategy is asymmetric induction by utilizing steric hindrance of neighboring groups. The stereogenic centers at the C4 and C5 positions of 2 were constructed by mCPBA epoxidation, and the C6 and C7 positions of 2 were produced by catalytic OsO4 dihydroxylation under highly stereoselective conditions.
Totally extraperitoneal laparoscopic inguinal hernia repair using a self-expanding nitinol framed hernia repair device: A prospective case series (2017)

TEP-IHR using a self-expanding nitinol framed hernia repair device is a safe technique in longterm follow-up. The technique is associated with a low incidence of postoperative pain, a short hospital stay and quick return to normal activities.
Transforming the Sandia 2{line_integral} optical performance measurement system to color (1996)

A monochrome 2f optical performance measurement system at Sandia. To meet the goals of an optical test method that can be done in a relatively short period of time, requires little space, uses ``off the shelf`` test equipment, and provides a quantitative measure adequate to address quality control requirements, necessitates conversion of the system to use color. This test method is based on common ray trace calculations for targets and images at the radius of curvature for spherical and parabolic (f/D>3) concentrators. The implementation of a color system involved changing hardware and software. Target design -- the layout, materials, and color selection -- is a primary consideration. As the system development neared completion, it was used in several applications to measure solar concentrator facet performance and evaluate system performance. Included in this testing was a side-by-side test with the SHOT system at the National Renewable Energy Laboratory. This paper discusses the development of the color system hardware, reviews the results of testing, and presents the color system software.
Synthesis and Characterization of Poly(benzoyl-1,4-phenylene)s. 2. Catalyst Coligand Effects on Polymer Properties (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and Characterization of Poly(benzoyl-1,4-phenylene)s. 2. Catalyst Coligand Effects on Polymer PropertiesYuechuan Wang and Roderic P. QuirkCite this: Macromolecules 1995, 28, 10, 3495–3501Publication Date (Print):May 1, 1995Publication History Published online1 May 2002Published inissue 1 May 1995https://pubs.acs.org/doi/10.1021/ma00114a001https://doi.org/10.1021/ma00114a001research-articleACS PublicationsRequest reuse permissionsArticle Views442Altmetric-Citations68LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Operational discipline in practice (2020)

Abstract A general guideline to improve operational discipline is required. Operational discipline can be improved with simple things such as floor level meeting (FLM), job cycle check (JCC), risk assessment (RA), daily safety audit (DSA), consequence analysis (CA), mechanical integrity (MI), incident investigation (II), management of change (MOC), behavior observation (BO), pre‐start up safety reviews (PSSR), process hazard analysis (PHA), job risk assessment (JRA), quantitative risk assessment (QRA), and process safety management (PSM) implementation. This article presents risks identified from floor level meetings, steps for job cycle check and risk sensitivity and procedure for daily safety audit and behavior observation audit. Consequence analysis, pre‐start up safety review and why tree analysis are discussed for improving operational discipline. Inclusion of consequence analysis in work instructions is discussed. Procedure for accident investigation is elaborated by investigating trainee unit shift engineer (USE) burning injury accident and why tree diagram is constructed and findings and recommendations are provided. PHA techniques (HAZOP, Failure Mode and Effect Analysis) methodology is presented to enhance operational discipline. This article is especially for those industries which are located in countries where PSM implementation is not mandatory and they are lacking in operational discipline.
Selective removal of the methyldiphenylsilyl protecting group using azide ion (1989)

S. J. Monger, D. M. Parry and S. M. Roberts, J. Chem. Soc., Chem. Commun., 1989, 381 DOI: 10.1039/C39890000381
Increased cardiovascular disease risk in women with a history of recurrent miscarriage (2018)

Women with a history of recurrent miscarriage differ in cardiovascular risk profile at a young age compared with women with no miscarriage. The findings support an opportunity to identify women at risk of cardiovascular disease later in life and a possible moment for intervention.
ChemInform Abstract: Sesquiterpene Glycosides from Cotton Oil Cake. (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Flexible M-Tooth Hybrid Micro-Structure-Based Capacitive Pressure Sensor With High Sensitivity and Wide Sensing Range (2021)

A novel flexible capacitive pressure sensor based on hybrid micro-structured (HM) polydimethylsiloxane (PDMS) dielectric layer was developed. The HM-PDMS with M-tooth structured patterns was fabricated using a laser engraved acrylic master mold. The top and bottom electrodes were fabricated by depositing silver (Ag) on flexible polyethylene terephthalate (PET) substrate using additive screen-printing process. The pressure sensor was assembled by sandwiching two HM-PDMS based dielectric layers between the top and bottom electrodes. The capability of the developed pressure sensor to detect a wide range of pressure was investigated by applying varying pressure from 0 to 1 kPa, 1 to 10 kPa, and 10 kPa to 40 kPa. A sensitivity of 51.36% kPa-1, 8.37% kPa-1, and 2.46% kPa-1 was obtained for the pressure ranges of 0 to 1 kPa, 1 to 10 kPa, and 10 to 40 kPa, respectively. The capacitive pressure sensor response, hysteresis, and repeatability of the fabricated pressure sensor is investigated and presented in this paper. To demonstrate the wide sensing range of the pressure sensor, the sensor was attached to face mask for breath monitoring applications that require low pressure sensing of ~20 Pa, and to the hand glove for fingertip pressure monitoring applications that require relatively high pressure sensing of ~3 kPa.
Functional Role of Laminin Carbohydrate (1984)

Previous work showed that tunicamycin suppresses glycosylation of laminin. In the present work, the role of glycosylation in the secretion of laminin and in the disulfide bonding of laminin subunits was studied, using tunicamycin to inhibit glycosylation. Tunicamycin inhibited extensively the secretion of laminin into culture medium and extracellular matrix even though the treated cells contained higher concentrations of laminin than the control cells. The laminin subunits synthesized in the presence of tunicamycin were disulfide bonded. Thus, suppression of glycosylation did not adversely affect disulfide bonding of the subunits, but did decrease the secretion of laminin. Glycosidases were also used to remove the carbohydrate of laminin to study the role of carbohydrate in the stability of laminin and in its interaction with another extracellular matrix component, heparin. The glycosidases removed about 73% of [3H]glucosamine. Both glycosidase-treated and untreated laminin were stable when incubated with cell lysate or culture medium. The glycosidase-treated laminin bound as efficiently as the untreated laminin to heparin. These results suggest that the presence of a carbohydrate moiety, at least at the level found in untreated laminin, is not essential in binding to heparin or in protecting laminin from proteolytic degradation in the cell or culture medium.
Multilevel Nonvolatile Memristive and Memcapacitive Switching in Stacked Graphene Sheets (2016)

We fabricated devices consisting of single and double graphene sheets embedded in organic polymer layers. These devices had binary and ternary nonvolatile resistive switching behaviors, respectively. Capacitance-voltage (C-V) curves and scanning capacitance microscopy (SCM) images were obtained to investigate the switching mechanism. The C-V curves exhibited a large hysteresis, implying that the graphene sheets acted as charging and discharging layers and that resistive switching was caused by charges trapped in the graphene layers. In addition, binary capacitive switching behaviors were observed for the device with a single graphene sheet, and ternary capacitive switching behaviors were observed for the device with the double graphene sheets. These results demonstrated that devices consisting of graphene sheets embedded in the polymer layers can be applied to multilevel nonvolatile memcapacitive devices as well as memristive devices.
No Escalation of Treatment: Moving Beyond the Withholding/Withdrawing Debate (2019)

This article refers to:Withholding and Withdrawing Life-Sustaining Treatment: Ethically Equivalent?Withdrawal Aversion and the Equivalence Test
Parallel logic simulation of VLSI systems (1995)

Article Free Access Share on Parallel logic simulation of VLSI systems Author: Roger D. Chamberlain Computer and Communications Research Center, Department of Electrical Engineering, Washington University, St. Louis, Missouri Computer and Communications Research Center, Department of Electrical Engineering, Washington University, St. Louis, MissouriView Profile Authors Info & Claims DAC '95: Proceedings of the 32nd annual ACM/IEEE Design Automation ConferenceJanuary 1995 Pages 139–143https://doi.org/10.1145/217474.217520Published:01 January 1995Publication History 21citation447DownloadsMetricsTotal Citations21Total Downloads447Last 12 Months23Last 6 weeks6 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Securing multimodal biometric data through watermarking and steganography (2013)

Many security concerns are raised through the storing and transferring of biometric data, which is sensitive and may be impossible to recover if lost, counterfeited, or hacked. Here, we present an approach for hiding biometric data, which utilizes a combination of asymmetric digital watermarking and steganography. The combination of these techniques enables the system to handle many issues associated with storing and transferring raw biometric data. What we propose is a multilayer framework that first, encodes eigen-features extracted from raw face images, into a fingerprint image. Sequentially, each watermarked fingerprint image is encoded within an arbitrary host image unrelated to biometrics or forensics, securing the image for transfer. The contributions of this work are as follows: developed an application of biometric watermarking face eigenfeatures into fingerprint images that are usable to provide authentication; developed the process of encoding the fingerprint images into an arbitrary host image, which provides an increased level of security and authentication; and the introduction of the concept of an asymmetric watermarking and steganography framework.
TCA cycle remodeling drives proinflammatory signaling in humans with pulmonary tuberculosis (2021)

The metabolic signaling pathways that drive pathologic tissue inflammation and damage in humans with pulmonary tuberculosis (TB) are not well understood. Using combined methods in plasma high-resolution metabolomics, lipidomics and cytokine profiling from a multicohort study of humans with pulmonary TB disease, we discovered that IL-1β-mediated inflammatory signaling was closely associated with TCA cycle remodeling, characterized by accumulation of the proinflammatory metabolite succinate and decreased concentrations of the anti-inflammatory metabolite itaconate. This inflammatory metabolic response was particularly active in persons with multidrug-resistant (MDR)-TB that received at least 2 months of ineffective treatment and was only reversed after 1 year of appropriate anti-TB chemotherapy. Both succinate and IL-1β were significantly associated with proinflammatory lipid signaling, including increases in the products of phospholipase A2, increased arachidonic acid formation, and metabolism of arachidonic acid to proinflammatory eicosanoids. Together, these results indicate that decreased itaconate and accumulation of succinate and other TCA cycle intermediates is associated with IL-1β-mediated proinflammatory eicosanoid signaling in pulmonary TB disease. These findings support host metabolic remodeling as a key driver of pathologic inflammation in human TB disease.
[Myocardial revascularization and radial artery: different surgical strategies and short-term results]. (2008)

The radial artery and the mammary artery can guarantee multiple arterial revascularization also for patients with contraindications to double mammary artery use. The four most common techniques for proximal radial artery anastomosis are not related to a higher operative risk and they can be used alternatively to reach the best surgical results.
Mulberry Leaf Extract Inhibits the Oxidative Modification of Rabbit and Human Low Density Lipoprotein. (2000)

In a previous study, we demonstrated that the intake of mulberry leaves or their 1-butanol extract (MLBE) reduced the concentration of serum lipids and atheromatous thickening of arterial intima in hypercholesterolemic rabbits. In the present study, we investigated the antioxidative activity of MLBE and isoquercitrin, the main component of MLBE. First, we determined the effect on a stable radical agent, finding that quercetin, isoquercitrin and MLBE scavenged the DPPH radical. We then determined the copper-induced oxidative modification of rabbit and human low-density lipoprotein (LDL). Oxidation of LDL was spectrophotometrically monitored by changes in absorbance at 234 nm accompanied by the formation of conjugated dienes, and measured the formation of thiobarbituric acid reacting substances (TBARS). Quercetin, an aglycone of isoquercitrin, inhibited the formation of conjugated dienes and TBARS by copper-induced oxidative modification of rabbit and human LDLs. MLBE and isoquercitrin also inhibited the oxidation of LDL. These results indicate that mulberry leaves inhibit the oxidative modification of LDL and suggest that mulberry leaves may had prevent atherosclerosis.
Adenosine increases anagen hair growth and thick hairs in Japanese women with female pattern hair loss: A pilot, double‐blind, randomized, placebo‐controlled trial (2008)

Adenosine upregulates the expression of vascular endothelial growth factor and fibroblast growth factor-7 in cultured dermal papilla cells. It has been shown that, in Japanese men, adenosine improves androgenetic alopecia due to the thickening of thin hair due to hair follicle miniaturization. To investigate the efficacy and safety of adenosine treatment to improve hair loss in women, 30 Japanese women with female pattern hair loss were recruited for this double-blind, randomized, placebo-controlled study. Volunteers used either 0.75% adenosine lotion or a placebo lotion topically twice daily for 12 months. Efficacy was evaluated by dermatologists and by investigators and in phototrichograms. As a result, adenosine was significantly superior to the placebo according to assessments by dermatologists and investigators and by self-assessments. Adenosine significantly increased the anagen hair growth rate and the thick hair rate. No side-effects were encountered during the trial. Adenosine improved hair loss in Japanese women by stimulating hair growth and by thickening hair shafts. Adenosine is useful for treating female pattern hair loss in women as well as androgenetic alopecia in men.
Polyfluorene-Based Light-Emitting Rod−Coil Block Copolymers (2005)

A series of novel well-defined polyfluorene-based rod−coil copolymers have been synthesized for application in light-emitting diodes (LEDs). These polymers were prepared by using polyfluorene macroinitiators to initiate the atom transfer radical polymerization of 2-(9-carbazolyl)ethyl methacrylate (CzEMA). The incorporation of CzEMA block successfully created energy transfer, and the findings showed that intramolecular energy transfer dominates in solution while intermolecular energy transfer plays a more important role in solid state. It was also demonstrated that energy transfer is more efficient for the block copolymers with respect to the corresponding polymer blends. Better spectral stability has been demonstrated with these copolymers in comparison to PF homopolymer through annealing studies. Interesting self-assembled nanostructures were observed for these polymers, which is dependent on the polymer composition. Electrochemical characterization indicated that the presence of the carbazole effectively raises the HOMO level with respect to the polyfluorene homopolymer, suggesting better hole injection properties. Preliminary LED experiments with these polymers indicated enhanced device performance compared to polyfluorene (PF) homopolymer. The results implied that rod−coil block copolymers with optoelectronic functionality are promising candidates for blue LED applications in terms of the suppression of green emission.
The effect of adenosine and allopurinol on the tolerance of the collapsed lung to warm ischemia. (1978)

The collapsed left lungs of dogs were subjected to 1 hour of normothermic ischemia in situ followed by immediate ligation of the contralateral pulmonary artery. Adenosine in a dose of 50 mg/kg prolonged the survival of the dogs significantly. In the survivors only transient changes in the chest x-ray were seen, and no changes in arterial oxygenation were observed. The pulmonary architecture was well preserved on histological studies 14 days after operation. Animals whose ischemic lungs were not protected by adenosine showed an immediate drop in arterial oxygenation and a massive infiltrate of the ischemic lung. Histological study of the lungs showed a complete breakdown of the capillary-alveolar barrier. Allopurinol alone was ineffective by itself and was not able to improve the survival achieved with adenosine further. We conclude that it is possible to prolong the tolerance of a deflated lung to normothermic ischemia by pretreatment with adenosine.
Understanding the evolution of Mycobacterium tuberculosis lineages using an integrated genomics and metabolomics approach (2020)

Despite being the number one cause of death from an infectious disease, little is known of the 7 phylogenetic lineages of Mycobacterium tuberculosis (Mtb). These lineages are thought to have adapted differently to their human hosts, as they are geographically localised. As a result, they show variation at the phenotype level, such as virulence and the ability to develop antibiotic resistance, and at a genomic level, such as in single nucleotide polymorphisms (SNPs). We have linked the differences in SNPs between lineages to differences in metabolites (i.e. what is ultimately produced by a cell). Through multi-omic integration of these datasets we have discovered lineage-specific metabolomic changes, potentially as a result of genomic adaptation. The differences between lineages will provide insight into new biological pathways to target and manipulate in future research.