gebhart/patrepeval huggingface dataset:
Maize orthologs of rice GS5 and their trans- regulator are associated with kernel development (2015)

从象米饭那样的模型种类的染色体信息能在在一个复杂染色体克隆基因帮助，例如玉米。这里，我们识别了在玉米贡献内核开发的米饭 GS5 的玉米 ortholog。ZmGS5 的表示层次的染色体宽的协会分析，并且它的 26 paralogs 中的 15 个，在染色体 7 上识别了一个 trans 管理者，它是象 BAK1 一样基因。我们作为 ZmBAK1-7 说出的这基因能调整 ZmGS5 的表示并且三 paralogs。候选人基因协会分析表明这五基因与玉米核被联系发展相关的特点。连接分析也检测了那 ZmGS5 和与印射的 QTL co 局部性的 ZmBAK1-7。在 Arabidopsis thaliana L 的 ZmGS5 的转基因的分析。在种子重量和房间数字显示出重要增加，建议 ZmGS5 可以有在影响种子开发的不同植物种类之中的保存功能。
Fibrin Network Structure: Modification by Platelets (1983)

Platelets play a fundamental role in haemostasis and thrombosis. They are known to undergo characteristic changes including release of subcellular material during clotting. The effect of subcellular platelet material on fibrin network structure, however, has not previously been investigated. Using opacity ratio, syneresis, permeation and electron microscopy it was found that subcellular platelet material extracted into NaCl is able to influence fibrin network structure of clots made from purified fibrinogen as well as platelet-poor plasma. Such clots had higher opacity ratio, reduced syneresis and lower permeability than control clots. Further, the responsible platelet material is heat labile and is released from the platelets during their aggregation with several common aggregating agents. Morphometric analysis of transmission electron micrographs has shown that fibrin fibres in plasma clots made in the presence of platelet subcellular material are thinner than those in control clots. In addition, plasma clots made in the presence of platelet extract had a higher resistance to fibrinolytic digestion than control clots. Thus, platelets play a hitherto undescribed role in regulating fibrin network structure.
Structure of epitaxial PbSe grown on Si(111) and Si(100) without a fluoride buffer layer (1996)

Epitaxial growth of PbSe on (111)- and (100)-oriented Si substrates without an intermediate buffer layer is studied. It is found that on Si(111) the orientation of the IV-VI layer can by varied from (100) at 200 °C to (111) at 400 °C substrate temperature. On Si(100), only (100)-oriented layers were obtained for the whole temperature range. (100)-oriented layers with thicknesses above 0.5 μm were cracked due to thermally induced mechanical strain on cooldown to room temperature. This strain cannot be relaxed by dislocation glide in the first glide systems as it is the case for (111)-oriented layers. The structural quality of (100)-oriented PbSe layers on Si(100) and Si(111) is inferior compared to layers grown with an intermediate BaF2/CaF2 or CaF2 buffer layer. This implies that the covalent/ionic PbSe/Si interface seems to impede high-quality epitaxy, contrary to the well known ionic/ionic IV-VI/IIa-fluoride interface.
Inflammatory linear verrucous epidermal naevus with auto-immune thyroiditis: coexistence of two auto-immune epithelial inflammations? (1994)

The copper vapour laser has in theory qualities which make it interesting in the treatment of cutaneous vascular malformations. In order to study the clinical effect of the copper vapour laser and to compare its effect with the effect of the argon laser, we treated 38 patients with port-wine stain or facial telangiectasia with the copper vapour laser. Thirty-one patients were evaluated and of these 24 were improved or much improved. Nineteen patients had previously been treated with the argon laser, and in this group the copper vapour laser had better effect than the argon laser in 8 patients and equal effect in 9 patients. In 7 patients side-effects like scarring or hyperpigmentation were noted after treatment with copper vapour laser.
Laser energy conversion (1989)

The conversion of laser energy to other, more useful, forms is an important element of any space power transmission system employing lasers. In general the user, at the receiving sight, will require the energy in a form other than laser radiation. In particular, conversion to rocket power and electricity are considered to be two major areas where one must consider various conversion techniques. Three systems (photovoltaic cells, MHD generators, and gas turbines) have been identified as the laser-to-electricity conversion systems that appear to meet most of the criteria for a space-based system. The laser thruster also shows considerable promise as a space propulsion system. At this time one cannot predict which of the three laser-to-electric converters will be best suited to particular mission needs. All three systems have some particular advantages, as well as disadvantages. It would be prudent to continue research on all three systems, as well as the laser rocket thruster. Research on novel energy conversion systems, such as the optical rectenna and the reverse free-electron laser, should continue due to their potential for high payoff.
Exploring Indigenous Lactobacillus Species from Diverse Niches for Riboflavin Production (2015)

Background: Riboflavin has received rather less attention in the past years, but interest is increasing because it is recognized as an essential component of cellular biochemistry, it is one of the vital vitamins required by human, bacteria, animals and plants.Today, bio production of riboflavin is competing with chemically synthesized one.Lactobacilli are well reckoned for their technological and probiotic significance and their exercise in dairy products for trade and industry.Materials and Methods: The present study was carried out to isolate and characterize riboflavin lactobacilli from various dairy and non-dairy sources of Indian origin.The isolates were subjected to phenotypic and genotypic characterizations followed by partial 16S rDNA sequencing.Results: As many as 40 isolates were identified as Lactobacilli and among them 14 were identified as L.plantarum, 5 as L. fermentum, 5 as L. delbrueckii subsp.bulgaricus, 4 L. brevis, 2 L. pentosus and 1 isolate as L. mucosae.Further isolates were screened for riboflavin production by chemical assay method and among all the tested isolates, 2 isolates viz.KTLF1 (L.fermentum) and KTLP13 (L.planatrum) have been observed to produce appreciable amount of riboflavin in MRS and RAM.Conclusion: These riboflavin producing lactobacilli can be used as a model for the development of strains that have the potential to produce an essential vitamin in situ which would contribute significantly to the functional value of certain fermented foods.
Nonlinear identification of skeletal muscle dynamics with sigma-point kalman filter for model-based FES (2008)

A model-based FES would be very helpful for the adaptive movement synthesis of spinal-cord-injured patients. For the fulfillment, we need a precise skeletal muscle model to predict the force of each muscle. Thus, we have to estimate many unknown parameters in the nonlinear muscle system. The identification process is essential for the realistic force prediction. We previously proposed a mathematical muscle model of skeletal muscle which describes the complex physiological system of skeletal muscle based on the macroscopic Hill-Maxwell and microscopic Huxley concepts. It has an original skeletal muscle model to enable consideration for the muscular masses and the viscous frictions caused by the muscle-tendon complex. In this paper, we present an experimental identification method of biomechanical parameters using Sigma-Point Kalman Filter applied to the nonlinear skeletal muscle model. Result of the identification shows its effective performance. The evaluation is provided by comparing the estimated isometric force with experimental data with the stimulation of the rabbit medial gastrocnemius muscle. This approach has the advantage of fast and robust computation, that can be implemented for online application of FES control.
Room‐Temperature Compression‐Induced Diamondization of Few‐Layer Graphene (2011)

Experimental and theoretical evidence for compression-induced diamondization of few-layer graphene is reported. Ab initio calculations predict that hydroxyl groups stabilize the sp3 hybridization of the two topmost carbon layers, creating a single layer of hydroxylated diamond, or diamondol, when graphene layers are compressed in the presence of water. Electric force microscopy measurements reveal a compression-induced charging inhibition of bilayer and multilayer graphene.
A new optical temperature measurement technique for semiconductor substrates in molecular beam epitaxy (1991)

A new optical temperature measurement technique for use in molecular beam epitaxy is demonstrated with GaAs substrates. The temperature of the semiconductor is inferred from its band gap, which is measured by the diffuse reflectivity of the substrate that is textured on the back surface. The method has a sensitivity of better than 2 °C, and an absolute accuracy limited by the accuracy with which the band gap is known as a function of temperature. It was found to be necessary to calibrate the measurement technique with a thermocouple in contact with the sample in order to achieve satisfactory accuracy at high temperatures. Measurements of the optical absorption edge of GaAs, show that the slope of the Urbach edge is independent of temperature from room temperature to 450 °C.
Optimistic deltas for WWW latency reduction (1997)

When a machine is connected to the Internet via a slow network, such as a 28.8 Kbps modem, the cumulative latency to communicate over the Internet to World Wide Web servers and then transfer documents over the slow network can be significant. We have built a system that optimistically transfers data that may be out of date, then sends either a subsequent confirmation that the data is current or a delta to change the older version to the current one. In addition, if both sides of the slow link already store the same older version, just the delta need be transferred to update it. Our mechanism is optimistic because it assumes that much of the time there will be sufficient idle time to transfer most or all of the older version before the newer version is available, and because it assumes that the changes between the two versions will be small relative to the actual document. Timings of retrievals of random URLs in the Internet support the former assumption, while experiments using a versi...
Application of the Multi-Beam Klystrons with Reverse Permanent Magnet Focusing System in RF Systems of the Compact Electron Accelerators (2006)

In our report we describe MBK application in four types of new generation compact electron accelerators which could not be built with their parameters using other type klystrons
Visualization of Literatures (1997)

Les differents modeles de litterature: modele bibliographique, modele bibliometrique, modele selon l'utilisateur... Presentation de nouveaux modeles qui offrent une visualisation des relations entre ecrits- relations le plus souvent basees en termes d'occurrences ou de cooccurrences. Utilisation d'affichages en 2 ou 3 dimensions
Partial-volume correction in PET: validation of an iterative postreconstruction method with phantom and patient data. (2007)

Iterative postreconstruction PVE correction generated more accurate uptake measurements in subcentimeter tumors for both phantoms and patients than the uncorrected values. The method eliminates the requirement for segmenting anatomic data and estimating tumor metabolic size or tumor background level. This technique applies a PVE correction to the mean voxel value within a VOI, yielding a more accurate estimate of uptake than the maximum voxel value.
P3‐019: Diverse neurological symptoms presenting severe dementia, psychiatric Symptoms and motor deficits in early‐onset familial Alzheimer's disease (2008)

In order to understand mechanism of AD, it is crucial to investigate the correlation between clinical features, radiological and biochemical features. Especially, it is important to examined possible causative genes of FAD families and molecular functions of genes. We disclose causative gene mutations and elucidate the common features and different points of clinical and radiological findings in four independent FAD families. We analyzed gene sequences of PS1, tau and α-synuclein as causative genes of these FAD families (FAD1–4). We also analyzed the correlation between temporal profiles of neurological symptoms and radiological findings of MRI/CT and SPECT. Two siblings in FAD1 family had common initial phenotype characterized by several neurological symptoms (dementia, apraxia, agnosia) and psychiatric symptom (apathy), with severe motor deficits since onset of the disease. PS1 M233L mutation was confirmed in these two cases. A proband of FAD2 family presented dementia and apathy, with rigid-bradykinetic parkinsonism with abnormal posture like forward flexion and dropped head, later, PS1 H163R was confirmed in this case. MRI of two siblings in FAD1 family showed that the temporo-parietal lobes and hippocampus were atrophied at the initial stage, then atrophies of the frontal lobe and basal ganglia were followed. SPECT showed low CBF in right parietal lobe. In FAD1 cases, Phosphorylated tau199 in CSF increased slightly, while Abeta42 in CSF was very low. MRI of the proband of FAD2 family showed severe temporal atrophy, and fronto-temporal atrophy, corresponding to low CBF in SPECT. While two cases of FAD3 resemble clinical and radiological findings of FAD2 case, those of FAD4 cases are reminiscent of FAD1 cases. Three FAD patients with PS1 mutation of M233L and H163R showed common clinical phenotype of dementia and psychiatric symptoms corresponded to the frontal and temporal lobe atrophies, in addition to parkinsonism. Other FAD cases also showed common and different clinical features. Clinical diversities of progression processes in deterioration of neuropsychiatric symptoms also exist between four FAD families. This suggested that PS1 mutation might possess some pathological functions to neurodegeneration in certain areas of FAD brains in addition to Aβ accumulation and NFT appearance.
Truncation of blood curves to enhance imaging and therapy with monoclonal antibodies (2000)

Targeting of monoclonal antibody (Mab) to solid tumor sites is a function of the blood curve of activity versus time. It has been suggested that the blood curve be artificially reduced to approach zero so that the contrast between tumor and blood uptake is maximized. We analyzed tumor uptake as a function of the time tc of blood curve truncation. By using a convolution approach, we were able to find the optimal times for setting the blood curve to zero in either diagnostic or therapeutic animal examples. Two iodinated cT84.66 anti-CEA engineered fragments, diabody and minibody, were considered using previous data from nude mouse studies involving the LS174T colorectal tumor model. Figures of merit (FOMs) were used to compare ordinary and truncated blood curves and their associated tumor accumulations. Using a 1231 label, it was seen that the appropriate time for diagnostic truncation occurred when tumor uptake, as measured, was a maximum. The corresponding point for therapy (with 1311 as a label) was at infinite time. We also demonstrated that the use of traditional indices led to ambiguities in the choice of truncation times. The traditional therapy index, the ratio of the integral of the tumor uptake to the integral of the blood uptake, was found to be a numerical constant independent of tc. This ratio was proved to be the integral of the tumor impulse response function. Use of such convolution techniques to assess truncation of the perfused material is probably also applicable to multistep processes as well as to lesion targeting with other tumor-specific pharmaceuticals.
Uncovering the Molecular Secrets of Inflammatory Breast Cancer Biology: An Integrated Analysis of Three Distinct Affymetrix Gene Expression Datasets (2013)

We show that IBC is transcriptionally heterogeneous and that all molecular subtypes described in nIBC are detectable in IBC, albeit with a different frequency. The molecular profile of IBC, bearing molecular traits of aggressive breast tumor biology, shows attenuation of TGF-β signaling, potentially explaining the metastatic potential of IBC tumor cells in an unexpected manner.
Automated Tool for Visual Progress Monitoring in Construction (2017)

This thesis focuses on determining innovative computer vision algorithms suitable for progress tracking and forming them into automated visual progress tracking framework. The main concept of this approach is reconstruction of an as-built 3D point cloud model of the object of interest based on the spatial information extracted from photographs or videos. The reconstructed as-built model is then compared to the as-planned model, and the progress is reported based on correlation of the as-built and the as-planned models. The perspective framework key components are Structure from Motion, Multi-View Stereo, Coherent Point Drift or Iterative Closest Point, and the Hausdorff distance. At the initial phase, Structure from Motion takes a set of images as an input, estimates camera parameters for each image and produces a sparse point cloud. Next, the obtained data passes to Multi-View Stereo and the dense point cloud is generated. At this stage, the acquired point cloud is the as-built model. The next phase is aligning of the reconstructed as-built model to the corresponding as-planned model. The alignment transformation is calculated with either Coherent Point Drift or Iterative Closest Point. Finally, having the point cloud aligned, the progress is estimated. This phase is performed in three steps. First, the Hausdorff distance is calculated. Second, the as-planned model is color coded with a binary palette, where one color corresponds to the completed parts of the construction object and another corresponds to the parts that are to be built. Third, the ratio of completed points to the number of all points is computed. Finally, the color-coded progress model and percentage of completion are reported to the end user. The perspective cutting edge libraries for Structure from Motion are COLMAP, OpenMVG, VisualSFM, TheiaSFM, and MVE. The chosen libraries for Multi-View Stereo are COLMAP, OpenMVS, CMVS, CMPMVS and MVE. The libraries selected for point cloud alignment are CPD (Coherent Point Drift) and libpointmatcher (Iterative Closest Point). Finally, the Hausdorff distance is computed with Meshlab. The chosen libraries are integrated into frameworks and tested on real case study data obtained from a construction company. The case study experiment indicated successful performance of the following frameworks: COLMAP-COLMAP-CPD-Meshlab, COLMAP-COLMAP-libpointmatcher-Meshlab, and OpenMVG-OpenMVS-CPD-Meshlab. These pipelines demonstrated their capability of performing reliable and fast progress identification. Thus, the specified software combinations are suggested for construction progress tracking. The proposed frameworks improve the cutting-edge computer vision construction project progress monitoring approaches in terms of reconstruction quality and computation time. In fact, the suggested progress monitoring approach allows to reduce progress identification time from a few hours to a few minutes.
Effect of polarity on Ni/InN interfacial reactions (2013)

Ni films on (0001) and (0001¯) InN exhibited different reaction kinetics upon annealing at 673K. Structural and chemical analysis using grazing incidence X-ray diffraction, transmission electron microscopy, and X-ray energy dispersive spectrometry indicated that an interfacial reaction did not occur between the Ni film and the In-polar (0001) InN layer. However, the N-polar face reacted with Ni to form the Ni3InNx ternary phase with an anti-perovskite structure. The difference in reactivity for Ni on In-face and N-face InN indicates that polarity alters the reaction and may also affect interactions between other metals and group III-nitride semiconductors.
STILBENE PHYTOALEXINS FROM DISEASED MULBERRY (1978)

Abstract Two stilbene phytoalexins were isolated from fungus-infected xylem tissue of mulberry shoots and characterized as trans-2,3′,4,5′-tetrahydroxystilbene (1, oxyresveratrol) and its 4′-(3-methyl-2-butenyl) derivative 2.
Celecoxib and Mucosal Protection: Translation from an Animal Model to a Phase I Clinical Trial of Celecoxib, Irinotecan, and 5-Fluorouracil (2007)

Maximum tolerated dose of irinotecan in FOLFIRI schedule with celecoxib is 200 mg/m2.
History and challenges of barium titanate: Part II (2008)

Barium titanate is the first ferroelectric ceramics and a good candidate for a variety of applications due to its excellent dielectric, ferroelectric and piezoelectric properties. Barium titanate is a member of a large family of compounds with the general formula ABO3 which is called perovskite. Barium titanate can be prepared using different methods. The synthesis method depends on the desired characteristics for the end application and the method used has a significant influence on the structure and properties of barium titanate materials. In this review paper, in Part II the properties of obtained materials and their application are presented.
Zeptomole detection sensitivity of prostate-specific antigen in a rapid microtitre plate assay using time-resolved fluorescence (2000)

Prostate-specific antigen (PSA) was detected in microtitre wells coated with a PSA-specific antibody using biotinylated antibody and streptavidin-coated, highly fluorescent 107 nm nanoparticles, which contained more than 30000 europium ions entrapped by beta-diketones. PSA was monitored directly on the surface of a well without any additional enhancement step. The sensitivity of the assay was 1.6 ng/L, corresponding to 50 fmol/L or 250 zeptomoles (250 x 10(-21) mol/L) of PSA. The high specific activity and low non-specific binding of the streptavidin-coated nanoparticles improved the sensitivity of the PSA assay 100-fold compared to the conventional europium-labelled streptavidin tracer in the same assay format. Additionally, the streptavidin-coated nanoparticle label made very rapid assays possible, due to the high affinity of the streptavidin-biotin complex and a high number of binding sites available for tracing the biotinylated antibody on the surface. Due to the inherent problems of tracing analyte with a complex of biotinylated antibody and streptavidin-coated nanoparticles, the streptavidin-coated nanoparticles reacting with the surface-captured analyte and biotinylated antibody was favoured and factors influencing this are discussed. This universal labelling technology can be applied to detect any biotinylated molecule, either in solution or on a solid phase, in order to improve detection sensitivities in many areas of biochemical analysis, such as cyto- and histochemistry, multianalyte DNA-chip assays and single-particle assays.
Improvement of a Potential Anthrax Therapeutic by Computational Protein Design (2011)

Past anthrax attacks in the United States have highlighted the need for improved measures against bioweapons. The virulence of anthrax stems from the shielding properties of the Bacillus anthracis poly-γ-d-glutamic acid capsule. In the presence of excess CapD, a B. anthracis γ-glutamyl transpeptidase, the protective capsule is degraded, and the immune system can successfully combat infection. Although CapD shows promise as a next generation protein therapeutic against anthrax, improvements in production, stability, and therapeutic formulation are needed. In this study, we addressed several of these problems through computational protein engineering techniques. We show that circular permutation of CapD improved production properties and dramatically increased kinetic thermostability. At 45 °C, CapD was completely inactive after 5 min, but circularly permuted CapD remained almost entirely active after 30 min. In addition, we identify an amino acid substitution that dramatically decreased transpeptidation activity but not hydrolysis. Subsequently, we show that this mutant had a diminished capsule degradation activity, suggesting that CapD catalyzes capsule degradation through a transpeptidation reaction with endogenous amino acids and peptides in serum rather than hydrolysis.