gebhart/patrepeval huggingface dataset:
Méthodes numériques pour la spatialisation sonore, de la simulation à la synthèse binaurale (2014)

Les recherches effectuees lors de ce doctorat furent initiees par un besoin industriel identifie par la societe Digital Media Solutions, a savoir la realisation d'un outil de spatialisation sonore au casque destine aux non-voyants. Malgre les nombreux dispositifs deja existants, les techniques de son 3D sur casque butent, depuis leur apparition, sur un obstacle majeur, qui empeche la realisation de produits de haute qualite. En effet, pour rendre l'illusion d'un espace sonore perceptible, il est necessaire d'individualiser l'ecoute pour chaque auditeur. Des mesures en laboratoire offrent des resultats convaincants, mais le processus n'est pas encore applicable au grand public. La modelisation mathematique de cette experience permet d'envisager de remplacer la mesure par une simulation numerique. Cette these propose a la fois un moteur de calcul numerique efficace et adapte au probleme pose, ainsi qu'un moteur de rendu audio 3D pour valider cette approche
Brightness Factor Matching for Gesture Recognition System Using Scaled Normalization (2011)

The rich information found in the human gestures makes it possible to be used for another language which is called the sign language, this kind of intuitive interface can be used with human-made machines/devices as well, we herein going to introduce a new gesture recognition system based on image blocking and the gestures are recognized using our suggested brightness factor matching algorithm, we have applied two different feature extraction techniques, the first one based on features extracted from edge information and the other one based on a new technique for centre of mass normalization based on block scaling instead of coordinates shifting; we have achieved 83.3% recognition accuracy in first technique with significant and satisfactory recognition time of 1.5 seconds per gesture, and 96.6 % recognition accuracy with recognition time less than one second by eliminating the use of edge detector which consumes time, this paper focuses on appearance based gestures.
Serine proteases identified from a Costelytra zealandica (White) (Coleoptera: Scarabaeidae) midgut EST library and their expression through insect development (2008)

Costelytra zealandica larvae are pests of New Zealand pastures causing damage by feeding on the roots of grasses and clovers. The major larval protein digestive enzymes are serine proteases (SPs), which are targets for disruption in pest control. An expressed sequence tag (EST) library from healthy, third instar larval midgut tissue was constructed and analysed to determine the composition and regulation of proteases in the C. zealandica larval midgut. Gene mining identified three trypsin-like and 11 chymotrypsin-like SPs spread among four major subgroups. Representative SPs were examined by quantitative PCR and enzyme activity assayed across developmental stages. The serine protease genes examined were expressed throughout feeding stages and downregulated in nonfeeding stages. The study will improve targeting of protease inhibitors and bacterial disruptors of SP synthesis.
Performance analysis of closed-loop transmit diversity in the presence of feedback delay (2001)

In this paper, a bit-error-rate (BER) analysis for closed-loop transmit diversity in a time-selective Rayleigh fading channel containing feedback delay is presented. In the absence of feedback delay, closed-loop transmit diversity always outperforms open-loop transmit for a given transmitted signal energy. This is no longer true in the presence of feedback delay. We derive closed-form expressions of the average BER for this case assuming QPSK and BPSK signaling. The results of the analysis are instrumental for comparing closed-loop with open-loop schemes under given operating conditions. In particular, we demonstrate that, for a given transmitted energy and number of transmit antennas, open-loop outperforms closed-loop at sufficiently fast channel fading. We also show that, for a given transmitted signal energy and fading rate, closed-loop outperforms open-loop for sufficiently large numbers of transmit antennas while the total average transmitted signal energy is kept constant. For some special cases, closed-form expressions for the fading rate at which the performance of open-loop is equal to closed-loop are obtained.
Crystal Structure of K2[C2O6]—First Proof of Existence and Constitution of a Peroxodicarbonate Ion This work was supported by the Deutsche Forschungsgemeinschaft (DFG) and the Fonds der Chemischen Industrie. Research was carried out in part at the National Synchrotron Light Source at Brookhaven National Laboratory, which is supported by the U.S. Department of Energy, Division of Materials Sciences and Division of Chemical Sciences. The SUNY X3 beamline at NSLS is supported by the Division of Basic Energy Sciences of the US Department of Energy under Grant No. DE-FG02-86ER45231. Work at Stony Brook was partially supported by the National Science Foundation. We thank Michael Knapp from beamline B2 (Hasylab) for the measurements at Hasylab. (2002)

By using high-resolution X-ray powder diffraction, we have determined the first crystal structure of a peroxodicarbonate compound, synthesized by electrocrystallization at −20°C. The constitution of the peroxodicarbonate anion was established and all structural details, including its conformation (see picture), can be understood qualitatively in terms of classical concepts of the chemical bond.
Advanced Methodology for the Detection of Smoke Point Heights in Hydrocarbon Flames (2018)

The American Society for Testing and Materials (ASTM) D1322 assesses the sooting tendency of fuels using smoke points. Recently, the fuel uptake rate measurement with threshold imaging (FURTI) method has improved smoke point determination. Herein, a precise and accurate detection of smoke point heights is investigated when tests are conducted with the FURTI method. First order gradients of the soot luminosity, recorded with a charge-coupled device camera, are used to detect the flame height. The analysis of several iso-octane/toluene calibration blends shows a significant diminution in the height experimental error in comparison to the ASTM D1322 standard, ranging from a minimum of 67% to a maximum of 86%. A low flame height bias, ranging from 1% to 5%, and a negligible sensitivity to the fuel sample composition is present when additional hydrocarbons are analyzed, owing to a high measuring accuracy and a robust height detection method.
Elasto-optic Effect and Its Spatial Anisotropy in Ca3TaGa3Si2O14 Crystals (2021)

An interferometric approach according to a single-pass Mach-Zehnder interferometer was used to investigate the photoelasticity of the Ca3TaGa3Si2O14 (CTGS) crystal. The highest number of sample orientations for piezo-optic studies was used to demonstrate the accuracy of piezo-optic coefficient determination. Basing on the matrices of piezo-optic coefficients and of elastic stiffness coefficients, all the coefficients pik of the elastic-optic matrix are computed. The acousto-optic efficiency is assessed for the highest value of pik coefficient. The data from CTGS are validated with the similar values for La3Ga5SiO14 (langasite) crystals. CTGS M2 = 1.66·10-15 s3/kg has the greatest acoustooptic figure of merit, which is two to three times higher, compared to langasite, and strontium borate, respectively and are frequently employed in the UV spectral range for acousto-optic light modulation.
ChemInform Abstract: Effects of Surface Pinning, Locking, and Adaption of Twins on the Performance of Magnetic Shape‐Memory Alloys (2013)

Abstract Review: 82 refs.
The rtA181S mutation of hepatitis B virus primarily confers resistance to adefovir dipivoxil (2014)

The study aimed to clarify clinical significance of hepatitis B virus (HBV) rtA181S mutation in Chinese HBV-infected patients. A total of 18 419 patients with chronic HBV infection from Beijing 302 Hospital were investigated. HBV complete reverse transcriptase region of polymerase was screened by direct sequencing, and the results were verified by clonal sequencing. Replication-competent mutant and wild-type HBV genomic amplicons were constructed and transfected into the HepG2 cells and cultured in the presence or absence of serially diluted nucleos(t)ide analogues. Intracellular HBV replicative intermediates were quantitated for calculating the 50% effective concentration of the drug (EC(50)). The rtA181S was detected in 98 patients with 12 kinds of mutational patterns. Genotype C and genotype B HBV infection occupied 91.8% and 8.2% in rtA181S-positive patients, in contrast to 84.6% and 15.4% in rtA181S-negative patients (P < 0.01). All rtA181S-positive patients had received nucleos(t)ide analogues. rtA181S was detected in multiple patients with virologic breakthrough. Phenotypic analysis of patient-derived viral strains showed that rtA181S, rtA181S+N236T, rtN236T and rtA181V strains had 68.5%, 49.9%, 71.4% and 66.2% of natural replication capacity of wild-type strain, and 3.7-fold, 9.8-fold, 7.9-fold and 5.6-fold increased EC(50) to adefovir dipivoxil (ADV). The rtA181S strain remained susceptible to lamivudine, entecavir and tenofovir, and ADV susceptibility was restored after the mutation was eliminated through site-directed mutagenesis. Rescue therapy with entecavir or combination therapy was effective in rtA181S-related ADV-refractory patients. The rtA181S mutation confers moderate resistance to ADV. It could be induced by either lamivudine or ADV and contribute ADV treatment failure.
ON ORDER AND TYPE OF AN ENTIRE DIRICHLET SERIES OF SEVERAL COMPLEX VARIABLES (1976)

The concepts of order and type of an everywhere convergent power series (entire function) were extended to an everywhere absolutely convergent Dirichlet series (entire Dirichlet series): $f(s)=\sum_{\alpha=1}^{\infty}a_{n}e^{*\lambda_{n}}$ ($s=\sigma+it,$ $\lambda_{1}>0,$ $\lambda_{n+1}>\lambda_{*}\rightarrow\infty$ with n) by Ritt [5], who also estimated the order and the type, so introduced, in terms of the coefficients of the series. The result of Ritt, expressing the order in . terms of the coefficients, was improved significantly by Azpeitia [1] who replaced the condition: $\lim_{n\rightarrow\infty}\inf(\lambda_{n}/\log n)>0$ by the weaker condition: $\lim_{n\rightarrow\infty}$ ( $\lambda_{n}$ log $\lambda_{n}/\log n$) $=\infty$ . In his subsequent paper, Azpeitia [2] derived inequalities for the order valid even without this restriction. Also, following the lines of Azpeitia [2], Jain and Gupta (P.N.) [3] improved considerably on a result of Kamthan [4], and consequently the corresponding results of $Yu[6]$ and Ritt [5] which expressed the type of $f(s)$ in terms of the coefficients. In the present paper, we have extended the results of Ritt [5] and $Yu[61$ to the entire Dirichlet series of several complex variables. It would be of much interest if our results could be improved on the lines of Azpeitia [2] and Jain and Gupta [3], in fact, we, at present, find it difficult. However, our interest shall continue to obtain the improved forms of these results. In the last section of this paper we state without proofs the results for a class of functions of infinite order analogues to our Theorem 1 and 2. For simplicity, we consider here only two variables, though our results can easily be extended to several complex variables.
Synthesis and Structure-Activity Relationships of Stilbene Retinoid Analogs Substituted with Heteroaromatic Carboxylic Acids (1995)

Retinoids elicit biological responses by activating a series of nuclear receptors. Six retinoid receptors belonging to two families are currently known: retinoic acid receptors (RAR alpha,beta,and gamma) and retinoid X receptors (RXR alpha,beta,and gamma). Stilbene retinoid analogs of retinoic acid (RA), such as (E)-4-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)prope n-1- yl]benzoic acid (TTNPB, 1) and (E)-4-[2-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)pro pen-1- yl]benzoic acid (3-methyl-TTNPB, 2), display differential RAR and RXR activities, depending on the substituent at C3 of the naphthalene ring. We report here structural modifications of the benzoate moiety of 2 that result in analogs with greater RXR selectivity as well as those with pan-agonist (activate both RAR and RXR receptors) activities, analyze the structural features that impart receptor selectivity, and describe a stereoselective method for the synthesis of these analogs. The biological activities associated with the RAR and RXR receptors were examined by testing representative examples with different receptor activation profiles for their ability to induce tissue transglutaminase (Tgase) activity in a human promyelocytic leukemia cell line (HL-60 cdm-1) and to inhibit tumor-promoter-induced ornithine decarboxylase (ODC) activity in hairless mouse skin. These results suggest that RAR agonists and RXR agonists may have different therapeutic applications. Finally, we show that RXR agonists are significantly reduced in teratogenic potency relative to RAR agonists and may therefore have significant advantages in clinical practice.
Hindering biofilm formation with zosteric acid (2010)

The antifoulant, zosteric acid, was synthesized using a non-patented process. Zosteric acid at 500 mg l(-1) caused a reduction of bacterial (Escherichia coli, Bacillus cereus) and fungal (Aspergillus niger, Penicillium citrinum) coverage by 90% and 57%, respectively. Calculated models allowed its antifouling activity to be predicted at different concentrations. Zosteric acid counteracted the effects of some colonization-promoting factors. Bacterial and fungal wettability was not affected, but the agent increased bacterial motility by 40%. A capillary accumulation test showed that zosteric acid did not act as a chemoeffector for E. coli, but stimulated a chemotactic response. Along with enhanced swimming migration of E. coli in the presence of zosteric acid, staining showed an increased production of flagella. Reverse transcriptase-PCR revealed an increased transcriptional level of the fliC gene and isolation and quantification of flagellar proteins demonstrated a higher flagellin amount. Biofilm experiments confirmed that zosteric acid caused a significant decrease in biomass (-92%) and thickness (-54%).
Mannose Binding and Epithelial Cell Adherence of Escherichia coli (1978)

The mannose-binding activity of several isolates of Escherichia coli was monitored by aggregometry with mannan-containing yeast cells. The velocity of yeast cell aggregation was found to correlate with the ability of the organisms to adhere to human epithelial cells. Mannose or its derivatives specifically inhibited or reversed epithelial cell adherence and yeast cell aggregation. Most of the adherent bacteria could be displaced within 30 min from the epithelial cells with methyl alpha-d-mannopyranoside, but not with other sugars tested. Cultures of E. coli were fractionated into nonadherent and adherent populations by adsorption with epithelial cells followed by elution of the adherent bacteria with methyl alpha-d-mannopyranoside. When the methyl alpha-d-mannopyranoside-displaced organisms were washed free of the sugar, they exhibited a high degree of mannose-binding activity and were heavily piliated. In contrast, the nonadherent fraction of organisms lacked detectable mannose-binding activity and were devoid of pili. Our results suggest that the binding activity of a mannose-specific lectin on the surface of E. coli can be quantitated directly on intact organisms, and the observed variations in the amount of mannose-binding activity among human isolates accounts for the variation in adherence of the organisms to mannose residues on epithelial cells.
The Use of Traction in the Treatment of Severe Spinal Deformity (2008)

Our study shows that patients with halo traction less frequently had a vertebral body resection, but achieved comparable deformity correction.
Biokinetic Modeling and Dosimetry for Optimizing Intraperitoneal Radioimmunotherapy of Ovarian Cancer Microtumors (2016)

According to the presented model, α-emitters are needed to achieve radiation doses high enough to eradicate microscopic tumors.
Optimal control of a slab reheating urnace (1966)

Information is presented about useful tools for systems studies and information about the reheat furnace system. An ability to solve optimization problems with a fairly large number of state variables indicates that it may be feasible to model other distributed parameter systems or continuous processes in a manner similar to the modeling of the reheat furnace. Also where state variable feedback is available for control purposes, computational techniques based upon the second variation may also lead directly to information useful for feedback control design.
Glutamine deprivation activates the PI3K/Akt pathway in intestinal epithelial cells (2007)

Larson, Shawn D. MD; Jackson, Lindsey N. MD; Chung, Dai H. MD, FACS; Evers, Mark B. MD, FACS Author Information
Optimal control and state estimation of lithium-ion batteries using reformulated models (2013)

First-principles models that incorporate all of the key physics that affect the internal states of a lithium-ion battery are in the form of coupled nonlinear PDEs. While these models are very accurate in terms of prediction capability, the models cannot be employed for on-line control and monitoring purposes due to the huge computational cost. A reformulated model [1] is capable of predicting the internal states of battery with a full simulation running in milliseconds without compromising on accuracy. This paper demonstrates the feasibility of using this reformulated model for control-relevant real-time applications. The reformulated model is used to compute optimal protocols for battery operations to demonstrate that the computational cost of each optimal control calculation is low enough to be completed within the sampling interval in model predictive control (MPC). Observability studies are then presented to confirm that this model can be used for state-estimation-based MPC. A moving horizon estimator (MHE) technique was implemented due to its ability to explicitly address constraints and nonlinear dynamics. The MHE uses the reformulated model to be computationally feasible in real time. The feature of reformulated model to be solved in real time opens up the possibility of incorporating detailed physics-based model in battery management systems (BMS) to design and implement better monitoring and control strategies.
Stability of etoposide solution for oral use (1992)

Journal Article Stability of etoposide solution for oral use Get access Howard L. McLeod, Pharm.D., Howard L. McLeod, Pharm.D. ASHP Foundation Cancer Immunotherapy Fellow Pharmaceutical Division, St. Jude Children's Research Hospital, Memphis, TN Search for other works by this author on: Oxford Academic Google Scholar Mary V. Relling, Pharm.D. Mary V. Relling, Pharm.D. Assistant Member, Pharmaceutical Division St. Jude Children's Research Hospital, and Assistant Professor, Department of Clinical Pharmacy, University of Tennessee, Memphis Address reprint requests to Dr. Relling at the Pharmaceutical Division, St. Jude Children's Research Hospital, 332 N Lauderdale, Memphis, TN 38101. Search for other works by this author on: Oxford Academic Google Scholar American Journal of Hospital Pharmacy, Volume 49, Issue 11, 1 November 1992, Pages 2784–2785, https://doi.org/10.1093/ajhp/49.11.2784 Published: 01 November 1992
Identification of Stress-Responsive Genes in Streptococcus mutans by Differential Display Reverse Transcription-PCR (2001)

Streptococcus mutans, which causes dental caries in the human oral cavity and occasionally causes infective endocarditis in the heart, withstands adverse environmental stress through diverse alterations in protein synthesis. Differential gene expression in response to environmental stress was analyzed by RNA fingerprinting using arbitrarily primed PCR with a panel of 11mer primers designed for differential display in Enterobacteriaceae. Dot and Northern blot hybridization confirmed that the transcription of several genes was up- or down-regulated following exposure to acid shock from pH 7.5 to 5.5. RNA of a gene designated AP-185 (acid-stress protein) was induced specifically by acid treatment, while RNA of GSP-781 (general-stress protein) was up-regulated significantly when bacteria were exposed to high osmolarity and temperature, as well as low pH. The deduced amino acid sequence of AP-185 shares homology (78% identity) with branched-chain amino acid aminotransferase. Cloning and sequence analysis of GSP-781 revealed a potential secreted protein of a molecular mass of about 43 kDa and with a pI predicted to be 5.5. Transcriptional levels of another gene, designated AR-186 (acid-repressed protein), which encodes putative aconitase, were repressed by acid treatment but were enhanced by plasma or serum components. Analogous results were identified in icd and citZ genes, and repression of these genes, along with AR-186, was also observed when they were exposed to high osmolarity and temperature. These results indicate that differential regulation of specific genes at the transcriptional level is triggered by different stress and that genes responsible for glutamate biosynthesis in the citrate pathway are coordinately regulated during the stress response of S. mutans.
Cosmetic assessment of triterpenoids in Ilex rotunda (2008)

Ilex (Aquifoliaceae) species are distributed widely in Eastern Asia (Japan, China, Taiwan and Indonesia), and some are used extensively in folk medicine.
Crystal structure of bis(4-pyridone)dichlorozinc(II), ZnCl2C5H5NO)2 (1998)

Article Crystal structure of bis(4-pyridone)dichlorozinc(II), ZnCl2C5H5NO)2 was published on April 1, 1998 in the journal Zeitschrift für Kristallographie - New Crystal Structures (volume 213, issue 1-4).
Synthesis of 6α,7α- and 6β,7β-aziridinoandrost-4-ene-3,17-diones and related compounds: potential aromatase inhibitors (1995)

The stereospecific synthesis of the novel 6β,7β- and 6α, 7α-aziridinoandrost-4-ene-3,17-dione 21 and 23 has been accomplished by treatment of vicinal azidohydrins 19 and 20 respectively with triphenylphosphane. Several related compounds (fused steroidal oxiranes, azidohydrins and an azide) were also synthesized. Reaction of (E)-6-hydroxyiminoandrost-4-ene-3β,17β-diol 2 with lithium aluminium hydride (LAH) gave, respectively, 5β,6β- and 5α,6α-aziridinoandrostane-3β,17β-diol 5 and 6. Although the 6,7-aziridines and their N-derivatives are poor inhibitors of human placental microsomal aromatase, most of the other compounds are modest inhibitors, while 7α-acetoxy-6β-azidoandrost-4-ene-3,17-dione 24 is a potent inhibitor of the enzyme (IC50-value = 0.40 µ mol dm–3).
Ring-Opening of ω-Substituted Lactones by Novozym 435: Selectivity Issues and Application to Iterative Tandem Catalysis (2008)

The enantioselectivity of the Novozym® 435 catalysed ring-opening of lactones is related to the conformation of the ester: cisoid lactones show S-selectivity or no selectivity while transoid lactones show a pronounced R-selectivity. The inability of Novozym 435 to polymerise 6-MeCL stems from its opposing selectivities for the alcohol and acyl moiety. By combining Novozym 435 with a racemisation catalyst, unreactive terminal alcohols in the S-configuration can be turned into reactive terminal alcohols of the R-configuration which can propagate. Combining 2 different catalysts that work together to accomplish propagation, also referred to as iterative tandem catalysis, is an elegant approach to convert a racemic monomer quantitatively into a homochiral polymer.