gebhart/patrepeval huggingface dataset:
Performance of Vehicular Nomadic Node Operation in Realistic Multicellular Wireless Networks (2017)

The need for 5G to adapt the radio access network to the spatial and temporal traffic variations makes the paradigm of moving networks essential. Dynamic network topology and moving cells through vehicular nomadic nodes (NN) will provide coverage extension and capacity improvement on demand as well as achieve reduced capital and operational expenditure when compared to fixed node deployment, such as microcells. Thus, it is of great importance to validate the envisioned performance of this paradigm change in a realistic scenario. To this end, this paper investigates the performance of NN operation in the context of a realistic multicellular wireless network, with the help of site-specific propagation modelling and real geographical databases. The results show that the NN operation can provide clear improvements relative to macrocell-only deployment and also propose the best values for the key systemic parameters that offer the optimum trade-off between throughput and complexity.
A general view on probabilistic logic programming (2003)

Probabilistic logic programming oers a way of dealing with both relational and uncertain knowledge. As research in this eld has lead to numerous formalisms, originating from diverse origins, it is not always easy to get a clear picture of this domain. In this work, we present a general \\framework&amp;quot; for looking at such formalisms. We show how several actual formalisms t into this view and how this leads to a clearer view on the relationships between them.
2D silicon nanopillars arrays for photonics (2015)

In this paper, particularities of ordered silicon nanopillars (Si NP) arrays formation by mean electron beam lithography and dry etching were studied. The optical and electrical properties of the Si NPs were investigated.
Learning query-dependent prefilters for scalable image retrieval (2009)

We describe an algorithm for similar-image search which is designed to be efficient for extremely large collections of images. For each query, a small response set is selected by a fast prefilter, after which a more accurate ranker may be applied to each image in the response set. We consider a class of prefilters comprising disjunctions of conjunctions (“ORs of ANDs”) of Boolean features. AND filters can be implemented efficiently using skipped inverted files, a key component of Web-scale text search engines. These structures permit search in time proportional to the response set size. The prefilters are learned from training examples, and refined at query time to produce an approximately bounded response set. We cast prefiltering as an optimization problem: for each test query, select the OR-of-AND filter which maximizes training-set recall for an adjustable bound on response set size. This may be efficiently implemented by selecting from a large pool of candidate conjunctions of Boolean features using a linear program relaxation. Tests on object class recognition show that this relatively simple filter is nevertheless powerful enough to capture some semantic information.
Multicore Erbium Doped Fibre Amplification Techniques (2021)

Koichi Maeda
TEMPORAL AND SPATIAL CHANGES IN ACIDITY AND ELECTRICAL CONDUCTIVITY OF FOREST PRECIPITATION (2000)

The chemistry of forest precipitatio n was monitored for three years at two sites in Chinese fir (Cunninghamia lanceolata ) plantations with different distances from a known atmospheric pollution sour ce. Precipitation acidity and electrical conductivity (EC) were significantl y el evated upon passage through forest canopies at both sites, and more so especiall y by stemflow. The average volume-weighted pH values for rainfall, throughfall and stemflow were 6.13,6.06 and 4.18, respectively, at the FFC forest site (furt her from emission source), and 5.86,5.67 and 3.37 at the XQF forest site. Acidi ty of rainfall and throughfall showed some seasonal trends,with minimal pH value s in summer and maximal in winter. The average volume-weighted EC values fo r rainfall, throughfall and stemflow were respectively 28.51, 63.71 and 240.85 a t FFC, and 36.99,66.41 and 501.85 at XQF. EC values of precipitation exhibit ed a strong seasonal pattern, with minimal values consistently found in summer m onths, intermediate in spring and fall, and maximal in winter, a pattern which a ppeared to be influenced greatly by the pattern of total precipitation. Acidity and electrical conductivity of precipitation at XQF near the emission source wer e significantly higher than that at FFC, which was relatively unaffected by air pollution.
Discovery and Optimization of Coking and Sulfur Resistant Bi- Metallic Catalyst for Cracking JP-8: From Thin Film Libraries to Single Powders (2014)

The recent development of solid oxide fuel cells (SOFC) capable of using liquefied petroleum gas (LPG) as a feedstock has created a viable high energy density technology for replacing the diesel generators and batteries used to create power in remote or mobile applications. Due to the unsurpassed volumetric energy density of liquid hydrocarbon fuels and the existing infrastructure for their distribution, it is preferable to transport and store diesel and jet fuel and catalytically crack it on-site to LPG. The ideal cracking catalyst must be capable of operating without excessively coking or being poisoned by sulfur present in the feedstock, and must be capable of being regenerated at temperatures similar to the reaction temperature, preferably using only air. These stringent requirements required rapidly identifying a series of base catalysts with high activity towards cracking, an additional series of potential additives to mitigate coking and promote regeneration, and the final verification of their combined properties to ensure optimal performance. Here we demonstrate a comprehensive and iterative high-throughput (HT) methodology for identifying such novel catalyst formulations with high activity towards cracking to LPG, which are capable of being operated for extended periods of time and regenerated in air multiple times without degradation in their activity. The approach combines a rapid, qualitative primary optical screen via thin-film techniques, a series of quantitative screens using mg powder quantities, and a final verification of the best samples using a single sample reactor. This versatile approach permitted the systematic study of a large phase-space of potential catalysts and additives combinations, ranging from noble metal promoted simple oxide catalysts to zeolite based catalysts. Initial studies focused on the identification of a catalyst with suitable activity, in excess of 20% conversion, using a 16-well reactor. This portion of the work focused on providing a comprehensive quantification of the product distribution of the different catalysts using industrially available catalyst formulations. Subsequently, thin-film samples with a spread of compositions deposited as nanoparticles on the surface of the most active catalysts were employed to screen bi-metallic additives for their relative coking and regeneration rates. Several additives with the highest figure of merit were recommended for a second round of screening of bi-metallic promoted zeolites in the 16-well reactor, where the emphasis shifted to evaluating the effect of both the additives and multiple regenerations on the product distribution. Final verification of the best additivemodified catalyst was obtained in a single reactor in which the catalyst was run under a highly concentrated feed for multiple days and demonstrated negligible degradation.
Fnip1 regulates skeletal muscle fiber type specification, fatigue resistance, and susceptibility to muscular dystrophy (2014)

Mammalian skeletal muscle is broadly characterized by the presence of two distinct categories of muscle fibers called type I "red" slow twitch and type II "white" fast twitch, which display marked differences in contraction strength, metabolic strategies, and susceptibility to fatigue. The relative representation of each fiber type can have major influences on susceptibility to obesity, diabetes, and muscular dystrophies. However, the molecular factors controlling fiber type specification remain incompletely defined. In this study, we describe the control of fiber type specification and susceptibility to metabolic disease by folliculin interacting protein-1 (Fnip1). Using Fnip1 null mice, we found that loss of Fnip1 increased the representation of type I fibers characterized by increased myoglobin, slow twitch markers [myosin heavy chain 7 (MyH7), succinate dehydrogenase, troponin I 1, troponin C1, troponin T1], capillary density, and mitochondria number. Cultured Fnip1-null muscle fibers had higher oxidative capacity, and isolated Fnip1-null skeletal muscles were more resistant to postcontraction fatigue relative to WT skeletal muscles. Biochemical analyses revealed increased activation of the metabolic sensor AMP kinase (AMPK), and increased expression of the AMPK-target and transcriptional coactivator PGC1α in Fnip1 null skeletal muscle. Genetic disruption of PGC1α rescued normal levels of type I fiber markers MyH7 and myoglobin in Fnip1-null mice. Remarkably, loss of Fnip1 profoundly mitigated muscle damage in a murine model of Duchenne muscular dystrophy. These results indicate that Fnip1 controls skeletal muscle fiber type specification and warrant further study to determine whether inhibition of Fnip1 has therapeutic potential in muscular dystrophy diseases.
Investigating The Use of a Point Of Care Salivary IgG Test In The Sporting Environment (2013)

Introduction The use of salivary diagnostics within the sporting community has gathered momentum in recent years; with the identification of hormone levels to assist in the optimisation of workloads, or antibody levels to assess individual recovery status and potential immune suppression. Immediate feedback for coaching and support staff via a Point of Care (POC) test would give a significant time advantage over standard laboratory techniques, which often reveal data to sporting squads only days later. This paper assesses a new POC product developed by Ipro for the rapid determination of salivary IgG in comparison to standard laboratory ELISA determination. Methods A total of 45 saliva samples were taken from a cohort of English Premier League Senior and Academy soccer players (22.4 ±7.2 yrs) using IPRO OFC collection kits. The samples were taken during routine monitoring: before training sessions. The same samples were assessed immediately on a POC Lateral Flow Device (LFD) to determine salivary IgG concentrations and then taken to a laboratory for subsequent analysis via ELISA within 4 hours of collection. The measurement range for ELISA was 1.75 - 105 μg/ml and POC test 1.6 - 120 μg/ml. Results Four samples exceded maximum values on both platforms and were excluded from the analysis. The remaining salivary IgG concentrations measured via ELISA ranged from 7.26 - 57.54 μg/ml and with the LFD from 2.26 - 51.81 μg/ml, with the mean difference 7.90 μg/ml. The relationship between the salivary IgG values obtained using the ELISA and POC test was represented by the formula: y = 0.8305x – 3.8109, with R2 0.8107. Conclusion The POC test used in the sporting environment showed good agreement with the ELISA method for the determination of salivary IgG. Given the quick data turnaround and efficiency in terms of cost, it represents a suitable alternative method for use in sports teams.
Nucleophilic Displacements in Supercritical Carbon Dioxide Using Silica-Supported Phase-Transfer Agents (2001)

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTNucleophilic Displacements in Supercritical Carbon Dioxide Using Silica-Supported Phase-Transfer AgentsJoseph DeSimone, Maurizio Selva, and Pietro TundoView Author Information Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-3290, and Dipartimento di Scienze Ambientali dell'Universita' Ca' Foscari, Calle Larga S. Marta, 2137-30123 Venezia, Italy [email protected]Cite this: J. Org. Chem. 2001, 66, 11, 4047–4049Publication Date (Web):May 4, 2001Publication History Received8 September 2000Published online4 May 2001Published inissue 1 June 2001https://pubs.acs.org/doi/10.1021/jo001337mhttps://doi.org/10.1021/jo001337mbrief-reportACS PublicationsCopyright © 2001 American Chemical SocietyRequest reuse permissionsArticle Views303Altmetric-Citations19LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Anions,Salts,Silica,Solvents,Substitution reactions Get e-Alerts
P149 DECREASED COLONIC ACTIVIN RECEPTOR-LIKE KINASE 1 DISRUPTS EPITHELIAL BARRIER INTEGRITY AND IS ASSOCIATED WITH A POOR CLINICAL OUTCOME IN CROHN’S DISEASE (2020)

Abstract Background and Aims Intestinal epithelial cell (IEC) barrier dysfunction is critical to the development of Crohn’s disease (CD). Mechanisms controlling colonocyte differentiation and barrier defects are understudied in CD. We recently reported increased expression of microRNA-31-5p (miR-31-5p) in colonic IECs of CD patients compared to non-IBD (NIBD) controls. In this study we identify and characterize the miR-31-5p target gene Activin Receptor-Like Kinase 1 (ALK1) as a key regulator of colonocyte maturation and IEC barrier integrity, specifically the functional impact of aberrant ALK1 signaling on colonocyte differentiation, barrier integrity, and clinical disease outcomes in CD. Methods MiR-31-5p target genes were identified in CD patients by integrative analysis of RNA- and small RNA-sequencing data from colonic mucosa and confirmed by quantitative RT-PCR (qPCR) in isolated colonic IECs. Functional characterization of ALK1 in colonic IECs was performed ex vivo using 2- or 3-dimensional cultured human primary colonic IECs. The impact of altered colonic ALK1 signaling for the risk of surgery and endoscopic relapse was evaluated by a multivariate regression analysis and a Kaplan-Meier estimator among CD patients. Results Integrative analysis of RNA- and small RNA-sequencing and follow-up qPCR identified ALK1 as a candidate target of miR-31-5p in the colonic IECs of CD patients. A 3’-UTR reporter assay with site-directed mutagenesis confirmed the direct regulation of ALK1 expression by miR-31-5p in HEK293T cells. Increased activation of ALK1 restricted the proliferation of primary colonic IECs in an EdU proliferation assay and down-regulated the expression of stemness-related genes, such as LGR5 and ASCL2. Activated ALK1 signaling directed the fate of human colonic IEC differentiation toward colonocytes. Down-regulated ALK1 signaling was associated with increased stemness-related gene expression and decreased colonocyte-specific gene expression in the isolated colonic IECs of CD patients compared to non-IBD controls. Activation of ALK1 did not affect colonic IEC migration in a wound healing assay, but enhanced epithelial barrier integrity in a trans-epithelial electrical resistance (TEER)-based permeability assay. Lower colonic ALK1 expression was associated with higher risks of surgery and endoscopic relapse in CD patients. Conclusion Decreased colonic ALK1 signaling disrupts colonic IEC barrier integrity and is associated with a poor clinical outcome in CD patients.
Feasibility analysis of high resolution tissue image registration using 3-D synthetic data (2012)

We used simulation to help select appropriate features and methods for image registration by estimating best-case-scenario errors for given data constraints in histological images. The results of this study suggest that much of the difficulty of stained tissue registration can be reduced to the problem of accurately identifying feature points, such as the center of nuclei.
Review of the Clinical Presentation of Uterine Fibroid and the Effect of Therapeutic Intervention on Fertility (2015)

Uterine fibroid is a common gynecological problem among women of reproductive age. The objective of this study was to review the common clinical presentation of uterine fibroid and assess the effect of therapeutic intervention on fertility. A retrospective descriptive study of 368 women, who were managed for uterine fibroid over a 5 years period (January 1st, 2008 to December 311st, 2012) was conducted at a University Teaching Hospital. The main outcome measures were common presentations, effect of treatment on fertility. Data were analyzed with Epi Info™ statistical software version 7.0. The incidence of uterine fibroids was 29.3%. Fibroids mainly affected those in the reproductive age group (31-40 years). The common clinical presentations- were abdominopelvic mass (100%), menorrhagia (95.7%), infertility (41.9%), anemia (32.9%), dysmenorrhoea (12.5%), abdominopelvic pain (15.8%), and urinary pressure symptoms (6.8%). Abdominal myomectomy (97.3%) was the main stay of treatment. The Odd Ratio of achieving pregnancy within two year of therapeutic intervention was 1.33 (0.27-6.60), p-value=0.0007, while the risk ratio of recurrent pregnancy loss was about three times less in those who had therapeutic interventions [3.56 (0.52-24.21)], p-value=0.11. Uterine fibroid presents with abnormal uterine bleeding and impaired fertility in women of reproductive age, and removal conferred fertility benefits in some cases.
A Double-blind Trial of a Nicotine Inhaler for Smoking Cessation (1993)

In this setting the nicotine inhaler appeared safe to use and increased success rates of smoking cessation attempts.
Microstructure and Magnetic Properties of CoFeHfO Rich Nanocrystalline Thin Films Application for High Frequency (2007)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
Insight into the Effects of Adipose Tissue Inflammation Factors on miR-378 Expression and the Underlying Mechanism (2014)

Our findings showed that adipokines induced miR-378 expression and revealed the most likely mechanism of adipokine-induced miR-378 dysregulation in human adipocytes. miRNAs have been shown to function in regulating obesity-related metabolic syndrome, and miR-378 may be a novel target for controlling adipose tissue inflammation. This study offers a theoretical basis for understanding systemic adipose tissue inflammation and may provide new strategies for clinical treatment.
Pharmacodynamics in the Evaluation of Drug Regimens (2002)

We believe, especially in an era of increasing antimicrobial resistance, that the integration of PK/PD models and stochastic techniques provides a powerful new tool to clinicians, researchers, and regulatory agencies alike. By using techniques such as these, we can begin to level the playing field so that PK/PD measures for therapeutic agents can be more accurately compared with greater certainty, and not be limited to discussions of susceptibility method variation or comparisons of MIC results.
Energy-Efficient Target Recognition using ReRAM Crossbars for Enabling On-Device Intelligence (2020)

Automatic target recognition (ATR) tasks which typically employ state-of-the-art deep learning inference techniques can be bottlenecked by energy expensive data movement operations in power-constrained edge devices. Consequently, computing paradigms such as in-memory-computing (IMC) are rapidly gaining traction in designing deep neural network (DNN) accelerators. Resistive random access memory (ReRAM), a technology which offers high storage density has emerged as a promising candidate for architecting IMC based DNN accelerators. In this work, we perform DNN inference using an ReRam based IMC architecture for enabling energy efficient ATR applications, on MSTAR dataset. Our proposed methodology outperforms commercial off-the-shelf general-purpose graphics processing units in terms of inference energy and throughput by ~22× and ~27× respectively.
Comparison of Functional and Metabolic Assessments in Preservation Techniques for Heart Transplantation (1991)

The present study compares simple hypothermic storage and hypothermic perfusion in a swine model of heart transplantation using metabolic and functional assessments. In both groups the hearts were initially protected with iso-osmolar potassium Tyers' cardioplegia. The donor hearts of group A were placed in simple hypothermic storage for 5 h. The donor hearts of group B were placed onto a perfusion apparatus for 5 h with perfusion pressure maintained at 28 cm of H2O and a myocardial temperature of 8-10 degrees C. The perfustate consisted of Tyers' solution with the addition of 2 mg/L of mannitol, 12.5 mg/L of glucose, 5 units/L of insulin, and 95% oxygen. The ischemic interval within both groups was 6 h, including orthotoipic transplantation. Investigation was conducted at three time periods: prepreservation (T1) in the donor, and postpreservation (T2) and immediately after loading (T3) in the recipient. Following volume loading for the hypothermic perfusion group there was significant improvement of myocardial function (cardiac index, p less than .05; stroke index, p less than .05) with no significant change in systemic vascular resistance, systemic blood pressure, and heart rate. There was also significant improvement in myocardial performance (p less than .05) for the hypothermic perfusion group following volume loading. Results of fatty acid turnover using 15-p-iodo (123I)-phenylpentodecanoic acid indicate significantly greater increase in metabolic rate for the perfusion group than for the hypothermic storage group. (p less than .05). This indicates improved metabolic status of the heart treated with the hypothermic perfusion technique. We conclude that a combination of functional and metabolic assessments is a good method for deduction of ischemic-reperfusion injury. We also conclude that hypothermic perfusion is superior to hypothermic storage for in vitro preservation of hearts for heart transplantation.