gebhart/patrepeval huggingface dataset:
Tracking control of 3 DOF parallel robots: Prototype design and experiments (2015)

Parallel robot has been usually used for pick-and place motion in very high speed environment to enhance the productivity. The high speed parallel robot is proposed for handling the solar cell in this paper. However the target processes are not just limited to the solar cell. The control algorithm is developed to achieve the high speed tracking control of pick-and-place motion. Also the prototype machine is designed and the cycle time and the repeatability of the proposed robot are validated. The method using the feedback and feedforward control is applied to the developed parallel robot and the performance is proven through the experiments. To improve the performance, the error for tracking and synchronization are simultaneously considered.
Transplantable glucagonomas derived from pluripotent rat islet tumor tissue cause severe anorexia and adipsia. (1995)

From pluripotent pancreatic rat islet tumor tissue we have previously reported the isolation of stable transplantable glucagonoma tumor phenotypes in rats characterized by acute onset of anorexia. We now report that these tumors also cause severe adipsia. Food and water intake is reduced by more than 95% and is immediately cured upon tumor removal. Four anorectic tumor lines were all characterized as glucagonomas with high levels of proglucagon mRNA, and of two tested both were associated with highly elevated plasma levels of glucagon as well as of Glp-1(7-36amide) in the host rat. This fetal processing pattern of proglucagon may be indirectly linked to the anorectic phenotype, since we have now isolated a non-anorectic glucagonoma with similar levels of proglucagon mRNA. Lack of anorexia/adipsia in SV-40-T-antigen driven glucagonomas in transgenic mice with similar fetal processing as reported by other suggests that our tumors produce a novel anorectic substance. This factor ranges among the most potent of its kind as a peripheral mediator involved in appetite and thirst regulation. In summary, the glucagonomas provide an interesting tool with which to study the nature of severe anorexia as well as adipsia, and the identification of the active substance(s) may provide novel therapeutics for the treatment of obesity-related disorders such as NIDDM.
Mining the equine gut metagenome: poorly-characterized taxa associated with cardiovascular fitness in endurance athletes (2022)

Emerging evidence indicates that the gut microbiome contributes to endurance exercise performance. Still, the extent of its functional and metabolic potential remains unknown. Using elite endurance horses as a model system for exercise responsiveness, we built an integrated horse gut gene catalog comprising ~25 million unique genes and 372 metagenome-assembled genomes. This catalog represents 4179 genera spanning 95 phyla and functional capacities primed to exploit energy from dietary, microbial, and host resources. The holo-omics approach shows that gut microbiomes enriched in Lachnospiraceae taxa are negatively associated with cardiovascular capacity. Conversely, more complex and functionally diverse microbiomes are associated with higher glucose concentrations and reduced accumulation of long-chain acylcarnitines and non-esterified fatty acids in plasma, suggesting increased ß-oxidation capacity in the mitochondria. In line with this hypothesis, more fit athletes show upregulation of mitochondrial-related genes involved in energy metabolism, biogenesis, and Ca<sup>2+</sup> cytosolic transport, all of which are necessary to improve aerobic work power, spare glycogen usage, and enhance cardiovascular capacity. The results identify an associative link between endurance performance and gut microbiome composition and gene function, laying the basis for nutritional interventions that could benefit horse athletes.
Zentrale Entwicklungen im Einzelhandel und ihre Beurteilung vor dem Hintergrund einzelhandelsbezogener Ziele der Raumordnungspolitik (2004)

Die Vielfalt an Betriebsformen und deren kontinuierliche Weiterentwicklung machen es notwendig, die Gegenüberstellung des raumordnungspolitischen Idealbildes mit den realen Entwicklungen im Einzelhandel auf eine geeignete Auswahl von Betriebsformen zu fokussieren, denen besondere Relevanz zukommt hinsichtlich ...
Non-data-aided timing synchronization for cooperative MIMO OFDM systems (2012)

In cooperative multiple-input multiple-output (MIMO) orthogonal frequency division multiplexing (OFDM) systems, signals transmitted from cooperating terminals arrive at the receiver on distinct timing due to diverse propagation delays. Therefore, timing synchronization is even more challenging in cooperative MIMO systems than in centralized MIMO configurations. Up to the present, various training sequence designs, along with synchronization algorithms, have been proposed. Among these data-aided approaches, a timing synchronization scheme utilizing unequal period synchronization patterns (UPSPs) was proposed. In this paper, from a non-data-aided perspective, we propose a generalized interleaved carrier assignment scheme that makes the resultant random OFDM data symbols themselves become UPSP-like, and develop a blind timing synchronization scheme accordingly. Simulation results show that the proposed non-data-aided approach with majority vote refinement (MVR) can achieve better performance than the original UPSP-based approach.
Active Vibration Isolation in Ships: A Pre-Analysis of Sound and Vibration Problems (2005)

Engine-induced sound and vibration levels in boats for professional and leisure use are in many cases unacceptably high in terms of comfort and environmental disturbance. Classical methods for pass ...
Further analysis of surface bond lengths measured for chemisorption on metal surfaces (1986)

This paper compares bond lengths deduced from the methods of surface crystallography with predictions from the Pauling–Schomaker–Stevenson approach and from a new alternative approach suggested by recent work of Brown and Altermatt. Examples considered are specifically for X—M surface bond lengths where atoms X from groups 16 or 17 are adsorbed on well-defined surfaces of a metal M. The alternative approach introduced here is parametrised with reference to structural data from solid compounds of formula MX. The two predictive approaches considered, when used together, appear to be quite adequate for guiding choices of trial model structures to be included in surface crystallographic analyses with low-energy electron diffraction (LEED); also they seem reasonable for checking the general reliability (or otherwise) of surface bond length data. Two further features introduced by this work are (i) evidence that the Cl—Ag distance reported by LEED for Cl adsorbed on the Ag(100) surface is broadly consistent with the structure of solid AgCl; (ii) evidence for S adsorbed on the Fe(110) surface that these analyses can guide investigations of lateral relaxations of surface metal atoms. As more reliable structural data become available, extensions of these analyses should help to identify the finer details in X—M bond lengths which result from the special coordination arrangements occurring at surfaces.
Poor Interoperability of the Adams-Harbertson Method for Analysis of Anthocyanins: Comparison with AOAC pH Differential Method (2013)

The poor interoperability of anthocyanin glycosides measurements by two pH differential methods is documented. Adams-Harbertson, which was proposed for commercial winemaking, was compared to AOAC Official Method 2005.02 for wine. California bottled wines (Pinot Noir, Merlot, and Cabernet Sauvignon) were assayed in a collaborative study (n=105), which found mean precision of Adams-Harbertson winery versus reference measurements to be 77 +/- 20%. Maximum error is expected to be 48% for Pinot Noir, 42% for Merlot, and 34% for Cabernet Sauvignon from reproducibility RSD. Range of measurements was actually 30 to 91% for Pinot Noir. An interoperability study (n=30) found Adams-Harbertson produces measurements that are nominally 150% of the AOAC pH differential method. Large analytical chemistry differences are: AOAC method uses Beer-Lambert equation and measures absorbance at pH 1.0 and 4.5, proposed a priori by Flueki and Francis; whereas Adams-Harbertson uses "universal" standard curve and measures absorbance ad hoc at pH 1.8 and 4.9 to reduce the effects of so-called co-pigmentation. Errors relative to AOAC are produced by Adams-Harbertson standard curve over Beer-Lambert and pH 1.8 over pH 1.0. The study recommends using AOAC Official Method 2005.02 for analysis of wine anthocyanin glycosides.
Ensemble and single molecule FRET analysis of the structure and unfolding kinetics of the c-kit promoter quadruplexes (2009)

FRET analysis has been used to examine the folded conformations and differing kinetic stabilities of two DNA G-quadruplexes (c-kit 1 and c-kit 2) derived from sequences found in the promoter of the c-kit proto-oncogene.
Plug-through energy monitor for plug load electrical devices (2015)

We present a low-cost, plug-through energy monitor for ubiquitous electrical monitoring of plug load devices in buildings. Using a non-invasive inductive current sensing technique, the current through a plug load device is measured without a series sensing element that breaks the circuit. This enables slim profile hardware, and eliminates the series resistor power dissipation inherent in traditional current sensing implementations. Our device is fabricated using a standard PCB process with a BOM around $5, and an inductive sense coil is printed directly into the PCB. The prototype can be embedded into an outlet faceplate and easily retrofits onto any existing outlet for long-term measurement of AC power parameters. The sensor includes low-power wireless connectivity with a range of approximately 120 feet through multiple walls. Voltage and current signals are sampled at 1920 Hz for handling non-linear loads, and the measured noise floor is approximately 2.4W with 120 V RMS mains.
RR interval analysis for detection of Atrial Fibrillation in ECG monitors (2008)

We investigate two RR irregularity measures suitable for Atrial Fibrillation (AFIB) detection in ECG monitors, one based on the absolute deviation and the other based on the difference between successive RR intervals. A sequence of RR intervals is fed to the irregularity measures after applying certain constraints on length and beat classifications to provide criteria for detection of AFIB. Receiver Operating Curves (ROC) are used to analyze and compare the performance of the two methods against MIT-BIH Arrhythmia Database, MIT-BIH AFIB Database and a proprietary AFIB Database.
Sensitivity analysis on electrical parameters for Permanent Magnet Synchronous Machine manufacturing tolerances in EV and HEV (2016)

Production processes of Permanent Magnet Synchronous Machines suffer from manufacturing tolerances because of assembly imperfections. This causes undesired deviations in the machine's performance and behavior. In particular, the equivalent circuit parameters of the machine are affected. Therefore, the validity of the electrical parameters of a reference machine is doubtful for sample machines. In this work, a sensitivity analysis is done in order to investigate the influence of design variables (e.g. rotor outer radius) on the electrical parameters. The aim is to show the importance of paying an attention to the parameters' deviations resulting from tolerances, to identify how the parameter deviations trend is, and which geometrical parameters have the most significant impact on the machine parameters. The study is done for an 18kW permanent magnet synchronous machine by changing the design variables in the tolerance band. Analysis results show that a mathematical model, that describes the deviations of electrical parameters, can be extracted.
Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D 3 (2001)

Steroid hormones are central regulators of a variety of biological processes. According to the free hormone hypothesis, steroids enter target cells by passive diffusion. However, recently we demonstrated that 25(OH) vitamin D(3) complexed to its plasma carrier, the vitamin D-binding protein, enters renal proximal tubules by receptor-mediated endocytosis. Knockout mice lacking the endocytic receptor megalin lose 25(OH) vitamin D(3) in the urine and develop bone disease. Here, we report that cubilin, a membrane-associated protein colocalizing with megalin, facilitates the endocytic process by sequestering steroid-carrier complexes on the cellular surface before megalin-mediated internalization of the cubilin-bound ligand. Dogs with an inherited disorder affecting cubilin biosynthesis exhibit abnormal vitamin D metabolism. Similarly, human patients with mutations causing cubilin dysfunction exhibit urinary excretion of 25(OH) vitamin D(3). This observation identifies spontaneous mutations in an endocytic receptor pathway affecting cellular uptake and metabolism of a steroid hormone.
Epicardial Adipose Tissue Is Associated with Plaque Burden and Composition and Provides Incremental Value for the Prediction of Cardiac Outcome. A Clinical Cardiac Computed Tomography Angiography Study (2016)

Epicardial adipose tissue volume is independently associated with plaque burden and maximum luminal narrowing by CCTA and may serve as an independent predictor for cardiac outcomes in patients at intermediate risk for CAD.
Anti-Migraine Drug Interactions with Cloned Human 5-Hydroxytryptamine 1 , Receptor Subtypes (1993)

Multiple 5-hydroxytryptamine (5-HT) receptors have been identified in humans. A subgroup of these receptors (designated 5-HT1 receptors) have been hypothesized to be involved in the mechanism of action of acute anti-migraine drugs. At present, this hypothesis cannot be tested directly in human tissues due to technical limitations. However, recent molecular biological advances have allowed for the development of assays employing cloned human 5-HT1 receptors expressed in cells by DNA transfection. This study analyzed the ability of ergotamine, dihydroergotamine, and 5-HT and sumatriptan to interact with the four known human 5-HT1 receptor subtypes. The four acute anti-migraine agents interacted with all 4 human 5-HT1 receptor subtypes with less than 1 microM affinity. However, drug affinities for the human 5-HT1B and 5-HT1D receptors correlate most closely with the rank order of clinical dosages used to treat a migraine attack. Therefore, these data indicate that human 5-HT1B and/or 5-HT1D receptors are likely to mediate the therapeutic efficacy of acute anti-migraine drugs.
Online Parameter Identification of Facet Growth Kinetics in Crystal Morphology Population Balance Models (2015)

Particle shape plays an important role in many industrial applications since it can have significant impact on both, processability of particles as well as the properties of the final product.For this reason modeling of the corresponding production process is crucial for developing efficient process optimization and control strategies.The shape evolution of crystals on the process scale can be described conveniently within the framework of morphological population balance modeling.In order of being a reliable tool for the prediction of the crystal shape distribution during the production process as well as for the design of suitable control and optimal production strategies, the models require the estimation of several parameters characterizing the growth rates of the different crystal facets.This is particularly challenging due to the infinite dimensional state space of the models.In this contribution online parameter estimation for the growth rates of L-glutamic acid cooling crystallization is presented.Using a Lyapunov-based approach the parameter adaption laws are computed directly from the infinite dimensional problem formulation.It will be shown that a reasonably fast convergence of the parameter estimates can be achieved even in the presence of measurement noise using appropriate filters.
CD95 (APO-1/FAS)-mediated apoptosis in cytokine-activated hematopoietic cells. (1998)

Elimination of peripheral T cells is crucially regulated via apoptosis through CD95 (APO-1/Fas) receptor ligand interaction. Because homeostasis in hematopoietic cells may also involve the CD95 system, we analyzed CD95 expression and sensitivity to CD95-induced apoptosis in human bone marrow cells. During hematopoiesis CD95 is differentially expressed on distinct cell types and at different maturational stages with an increase in receptor density from early CD34+ stem cells to maturing progenitor cells. Incubation of bone marrow cells with anti-APO-1 (anti-CD95) induces apoptosis in maturing erythroblasts and neutrophil progenitors (10-19%) and to a lesser extent in stem cells and myeloblast/proerythroblasts (4-9%). On in vitro culture, CD95 expression is particularly upregulated on activated CD71+ myeloid progenitors. Hematopoietic cytokines (stem cell factor, interleukin-3, granulocyte macrophage colony-stimulating factor [GM-CSF], and granulocyte-colony-stimulating factor [G-CSF] contribute to upregulation of CD95 on bone marrow cells. CD95-induced apoptosis in activated progenitors was markedly enhanced by activating cytokines. Thus cytokines known to mediate proliferation, survival, and maturation, in hematopoiesis do not prevent, but rather facilitate negative growth regulation via the CD95 pathway in activated cells. Deregulation of the CD95 system may provide a molecular basis for the development of bone marrow failure or immune-mediated cytopenia. Defects in the CD95 pathway may contribute to the development of hematopoietic malignancy by abrogating CD95-mediated growth control of activated cells.
High-Throughput Sequencing of RNA Silencing-Associated Small RNAs in Olive (Olea europaea L.) (2011)

Small RNAs (sRNAs) of 20 to 25 nucleotides (nt) in length maintain genome integrity and control gene expression in a multitude of developmental and physiological processes. Despite RNA silencing has been primarily studied in model plants, the advent of high-throughput sequencing technologies has enabled profiling of the sRNA component of more than 40 plant species. Here, we used deep sequencing and molecular methods to report the first inventory of sRNAs in olive (Olea europaea L.). sRNA libraries prepared from juvenile and adult shoots revealed that the 24-nt class dominates the sRNA transcriptome and atypically accumulates to levels never seen in other plant species, suggesting an active role of heterochromatin silencing in the maintenance and integrity of its large genome. A total of 18 known miRNA families were identified in the libraries. Also, 5 other sRNAs derived from potential hairpin-like precursors remain as plausible miRNA candidates. RNA blots confirmed miRNA expression and suggested tissue- and/or developmental-specific expression patterns. Target mRNAs of conserved miRNAs were computationally predicted among the olive cDNA collection and experimentally validated through endonucleolytic cleavage assays. Finally, we use expression data to uncover genetic components of the miR156, miR172 and miR390/TAS3-derived trans-acting small interfering RNA (tasiRNA) regulatory nodes, suggesting that these interactive networks controlling developmental transitions are fully operational in olive.
Audio compression at low bit rates using a signal adaptive switched filterbank (2002)

A perceptual audio coder typically consists of a filter-bank which breaks the signal into its frequency components. These components are then quantized using a perceptual masking model. Previous efforts have indicated that a high resolution filter-bank, e.g., the modified discrete cosine transform (MDCT) with 1024 subbands, is able to minimize the bit rate requirements for most of the music samples. The high resolution MDCT, however, is not suitable for the encoding of non-stationary segments of music. A long/short resolution or "window" switching scheme has been employed to overcome this problem but it has certain inherent disadvantages which become prominent at lower bit rates (<64 kbps for stereo). We propose a novel switched filter-bank scheme which switches between a MDCT and a wavelet filter-bank based on the signal characteristics. A tree structured wavelet filter-bank with properly designed filters offers natural advantages for the representation of non-stationary segments such as attacks. Furthermore, it allows for the optimum exploitation of perceptual irrelevancies.
Information-Theoretic Timed-Release Security: Key-Agreement, Encryption, and Authentication Codes. (2012)

In this paper, we study timed-release cryptography with information-theoretic security. As fundamental cryptographic primitives with information-theoretic security, we can consider key-agreement, encryption, and authentication codes. Therefore, in this paper we deal with information-theoretic timed-release security for all those primitives. Specically, we propose models and formal-izations of security for information-theoretic timed-release key-agreement, encryption, and authenti-cation codes; we also derive tight lower bounds on entities &amp;apos; memory-sizes required for all those ones; and we show optimal constructions of all those ones. Furthermore, we investigate a relationship of mechanisms between information-theoretic timed-release key-agreement and information-theoretic key-insulated key-agreement. It turns out that there exists a simple algorithm which converts the former into the latter, and vice versa. In the sense, we conclude that these two mechanisms are essentially close. 1
Maximum-Likelihood Deconvolution in the Spatial and Spatial-Energy Domain for Events With Any Number of Interactions (2012)

In previous works, maximum-likelihood expectation-maximization deconvolution for two-interaction events within a single CdZnTe detector with dimensions of was implemented. This deconvolution method is capable of estimating the source image for each energy range as well as the incident spectrum for each direction around the detector. To improve the detection efficiency and the image resolution, we have built a four-detector array system; each detector has dimensions of . Using this detector-array system, from a Co-60 measurement, 41.5% of recorded events in the energy window from 1100 keV to 1200 keV are two-interaction events. The goal of this work is to increase the efficiency of this deconvolution algorithm by extending the calculation of the system response functions to events with other number of interactions. We first analytically extend the system response function calculation to three-interaction events by deriving the probability density function, considering the measurement noise, and integrating over the digitization and pixelation volume. The system response function is then simplified, modularized, and extrapolated to events with other numbers of interactions from an array system. By including events with any number of interactions in the system model, imaging makes use of all recorded events, and the angular resolution is improved. This deconvolution algorithm is applicable to any gamma-ray detector system that has the capability of recording 3D interaction location and energy deposition for each interaction.