gebhart/patrepeval huggingface dataset:
It's Not Easy Being Three: The Approximability of Three-Dimensional Stable Matching Problems (2014)

In 1976, Knuth asked if the stable marriage problem (SMP) can be generalized to marriages consisting of 3 genders. In 1988, Alkan showed that the natural generalization of SMP to 3 genders ($3$GSM) need not admit a stable marriage. Three years later, Ng and Hirschberg proved that it is NP-complete to determine if given preferences admit a stable marriage. They further prove an analogous result for the $3$ person stable assignment ($3$PSA) problem. In light of Ng and Hirschberg's NP-hardness result for $3$GSM and $3$PSA, we initiate the study of approximate versions of these problems. In particular, we describe two optimization variants of $3$GSM and $3$PSA: maximally stable marriage/matching (MSM) and maximum stable submarriage/submatching (MSS). We show that both variants are NP-hard to approximate within some fixed constant factor. Conversely, we describe a simple polynomial time algorithm which computes constant factor approximations for the maximally stable marriage and matching problems. Thus both variants of MSM are APX-complete.
The contribution of vitreoretinal surgery to the management of refractory glaucomas (1999)

Vitreoretinal techniques, although not new, are only gradually being recognized in the management of refractive glaucoma. Besides rare but established indications for vitrectomy, as in malignant glaucoma, vitreoretinal surgery may become even more valuable by offering an alternative outflow route to the choroid that remains open and functional. Vitreoretinal surgery in neovascular glaucoma is primarily meant to be antivasoproliferative surgery. Vitrectomy-lensectomy accesses the eye for panretinal laser coagulation, the only effective treatment of ocular neovascularization so far. Vitrectomy is a way of interfering with the pathogenesis of ocular new vessel formation, which otherwise inevitably leads to phthisis.
Effect of an herbal/botanical supplement on recovery from delayed onset muscle soreness: a randomized placebo-controlled trial (2014)

These data suggest that compared to placebo, StemSport supplementation does not improve outcome measures related to muscle recovery after acute upper-arm induced DOMS.
Coherence waves (1999)

In 1955 Wolf noticed that the mutual coherence function Γ obeys two wave equations [Proc. R. Soc. London230, 246 (1955)]. The physical optics of this finding is thoroughly presented in Mandel and Wolf’s recent monograph [Optical Coherence and Quantum Optics (Cambridge U. Press, Cambridge, UK1995)]. We discuss those coherence waves in the spirit of optical signal processing. The term coherence waves is justified if one accepts the following paradigm: A wave is whatever obeys the wave equation.
Getting to me: exporting semantic social network from Facebook (2008)

Information sharing forms a large component of the Social Web as web users become citizens within the web sphere. Within ‘walled garden’ services they interact socially with their peers through blog posts, image sharing and writing on one another’s ‘walls’. Porting this data for reuse opens up the social graph associated with the user. In this paper we present work to export Semantic information from the social networking site Facebook using the FOAF ontology by mashing up several Web 2.0 services. We explain the details of our approach and how it supports the data portability movement.
Interferon: mechanisms of action and clinical value. (1983)

The antiviral and antitumor mechanisms of action, pharmacokinetics, dosage considerations, and adverse effects of interferon are reviewed, and the results from clinical studies are summarized. Interferons are proteins that can induce a nonspecific resistance to viral infection by several mechanisms, including the inhibition of protein synthesis, inactivation of viral RNA, and enhancement of phagocytic and cytotoxic mechanisms. There are three classifications of interferons on the basis of their antigenic specificities--alpha (alpha), beta (beta), and gamma (gamma) interferon. Interferon is not absorbed from the gastrointestinal tract because it is a protein susceptible to proteolytic digestive enzymes. However, the absorption of alpha-interferon by the intramuscular and subcutaneous routes is nearly complete; peak serum concentrations occur at approximately two hours and four hours following i.m. and s.c. injections, respectively. The usual method of administration is by intramuscular injection, and the doses range from 1 to 10 million units per injection. Since blood concentrations decrease sharply within 24 hours, interferon is usually given on a daily basis, and the duration of therapy varies according to patient response. Adverse effects from interferon are generally transient and reversible. Some success has been reported with the use of interferon in the treatment of chronic hepatitis B infection. Acute fulminant hepatitis infection has also been treated with interferon. Patients with cytomegalovirus infection treated with interferon showed a decrease in the urinary virus but no important clinical benefits. The treatment of varicella-zoster (chicken pox) virus has been successful. The use of interferon by injection to treat influenza and the common cold seems unlikely because of its short duration of action and the self-limited nature of these infections. Varying success has been obtained when malignant tumors have been treated with interferon. Many types of viral infections and tumors have been treated with interferon with varying results. More research must be conducted before a final analysis of the clinical value of interferon can be made.
Quantitative computed tomography in porcine lung injury with variable versus conventional ventilation: Recruitment and surfactant replacement* (2011)

Quantitative computed tomography analysis confirms lung recruitment with biologically variable ventilation in a porcine oleic acid injury model. Surfactant replacement with biologically variable ventilation provided no additional recruitment benefit and may in fact be harmful.
Supplementary Figure 9 from GSK-3α Promotes Oncogenic KRAS Function in Pancreatic Cancer via TAK1–TAB Stabilization and Regulation of Noncanonical NF-κB (2023)

&lt;p&gt;PDF file - 263K, Kras regulates GSK-3α mRNA levels. HKRAS cells were transiently transfected with non-targeting control or KRAS siRNA. RNA was isolated, reverse transcribed to cDNA and real time RT-PCR performed for Kras and GSK-3α. Gus B was used as endogenous control.&lt;/p&gt;
Broadband upgrade of an operating narrowband single-fiber passive optical network using coarse wavelength division multiplexing and subcarrier multiple access (1998)

We demonstrate an overlay of a broadband passive optical network (PON) on the same fiber network as an operating baseband digital system. The baseband system is modeled after current-generation narrowband PONs, and the two PONs can be operated simultaneously. The broadband PON incorporates coarse wavelength division multiplexing to increase the downstream bit rate, and subcarrier multiple access for the upstream upgrade. We examine the RF interference between baseband and subcarrier signals, and provide guidelines on channel spacing and means for accommodating differing power levels for the two signals. The broadband architecture described here provides a graceful upgrade path for providing advanced digital services on a PON without having to modify the network or terminal equipment used for providing narrowband services.
Field Safety in Uncontrolled Environments: A Process-Based Guidebook (2005)

“Adventures, of course, are always associated with exploration. Yet they are the one thing which a real explorer tries to guard against. My favorite quotation is Stefansson’s dicutm: ‘Adventures are a mark of incompetence.’ It says so much in a very few words. It means that if you have an adventurous expedition you did not prepare yourself adequately. Adventures are a nuisance. They interface with work... If the explorer has a clear-cut problem to solve and an honest desire to do something really worthwhile he will prepare against adventures.” 

Although some degree of risk is inherent in every human activity, a primary goal of all field activities should be the safety and health of participants and staff. Those who sponsor, organize, and participate in these field activities have a responsibility to promote and support safety while achieving their technical, educational, or business objectives.

No one goes into the field with the intention of getting injured or killed. Most accidents, at root, result from a loss of perspective, a narrowing of focus, or developing tunnel vision: “I only wanted to get abetter look at the rocks by climbing up the cliff/leaning out of the boat/leaving the trail.” “Yes, people get hurt doing_, but it’s not going to happen to me.” It’s like driving down the road only looking ahead but never left, right, or behind—most of the time we get away with it, but such tunnel vision leaves us vulnerable to accidents. And, unfortunately, when an accident happens, it happens with such suddenness and severity that it breaks a person’s life in two forever, into “before” and “after.”
Tenascin function and regulation of expression. (1993)

Tenascin is a large hexameric extracellular matrix protein. Each subunit consists of a linear array of the following structural domains: an N-terminal cysteine-rich region and heptad repeats both involved in the oligomerization, followed by EGF-like repeats, fibronectin type III domains and a C-terminal globular domain homologous to fibrinogens. Depending on the species, the number of EGF-like repeats as well as of the fibronectin type III repeats differs. A model proposing a new nomenclature for the numbering of the fibronectin type III repeats is presented. It enables the assignment of corresponding repeats from different species and shows that for human tenascin several more alternatively spliced fibronectin type III repeats have been described than for chicken or mouse tenascin. Tenascin is generally classified as an anti-adhesive protein, since many cells do not adhere to tenascin or if they adhere they do not spread. The addition of tenascin can also lead to the loss of focal contacts in well spread cells. On the other hand growth cones adhere well to tenascin and a tenascin substrate can support neurite extension. Using recombinant fragments of tenascin we could identify an adhesive as well as an anti-adhesive region within one tenascin subunit. The major interest in tenascin was prompted by its interesting tissue distribution. Tenascin is often transiently expressed during organogenesis, tissue remodeling, cell migration and the development of the nervous system. We thus investigated possibilities to regulate tenascin expression in primary chick embryo fibroblast cultures.(ABSTRACT TRUNCATED AT 250 WORDS)
Autoluminescence-Free Dual Tumor Marker Biosensing by Persistent Luminescence Nanostructures (2019)

Persistent luminescence materials (PLMs) have been capturing more and more attention in biosensing, which is ascribed to the autoluminescence-free background, no requirement of illumination in situ, and high signal-to-noise ratio. PLMs with tunable persistent luminescence and desired decay patterns are still required to meet the demands of multiple bioassays and time-resolved fluoroimmunoassays. Herein, persistent luminescence nanorods with distinct decay patterns are prepared by doping Mn2+, Mo6+, Cr3+, and Sr2+ in the Zn2GeO4 (ZGO) host material, and persistent luminescence nanoparticles are synthesized by doping Cr3+ in the ZnGa2O4 (ZGC) host material. Green-emitted ZGO:Mn NRs and NIR-emitted ZnGa2O4:Cr (ZGC) NPs show slow luminescence decay rates and noninterfered colors and are alternative probes for the dual detection of prostate specific antigens and carcinoembryonic antigens (CEAs). The limits of detection are as low as 8.9 fg mL–1 PSA and 72 fg mL–1 CEA. The nanoprobes are capable of monitoring the CEA level in the human serum matrix. This work provides a new window for the fabrication of multiplex colored PLMs with desired decay patterns, which were used in high throughput cancer early screening, cancer diagnostics, and time-resolved fluoroimmunoassay.
November Meeting of the Northeastern Section (1967)

"November Meeting of the Northeastern Section." The American Mathematical Monthly, 74(3), p. 351
Quality really matters: the need to improve specimen quality in biomedical research (2012)

Contemporary pathological and molecular analysis depends on high quality human biospecimens. Poor biospecimen quality may compromise such analyses and the resultant inaccurate data published in scientific papers may be contribute to low reproducibility in the biomedical literature and adversely impact clinical translation. Editors of research journals play a key role in improving sample quality in biomedical by implementing established guidelines. The Editors of Histopathology and The Journal of Pathology will now require that researchers follow the BRISQ guidelines (Biospecimen Reporting for Improved Study Quality) in their papers and hope that this will be a model adopted by other journals in this domain.
Sulfur recovery from H/sub 2/S and SO/sub 2/-containing gases (1977)

Sulfur is recovered from gases containing H/sub 2/S and SO/sub 2/ by absorption of the H/sub 2/S and SO/sub 2/ in a glycol absorbent, and reaction of the H/sub 2/S and SO/sub 2/ in solution in the absorbent in the presence of a solid catalyst.
High Cardiac Angiotensin-II-Forming Activity in Infarcted and Non-Infarcted Human Myocardium (2000)

The aims of this study were to compare human cardiac angiotensin-II-forming activity (AIIFA) between the intact area of control autopsy hearts without cardiac disease (n = 10) and the infarcted or non-infarcted area of autopsy hearts with myocardial infarction (MI, n = 7) and to determine responsible angiotensin-II-forming enzymes. Cardiac total and chymase-dependent AIIFAs were significantly higher in the infarcted and non-infarcted myocardium than those in non-MI heart, while angiotensin-converting enzyme-dependent AIIFA increased only in the infarcted myocardium. The density of chymase antibody-positive mast cells in the non-infarcted area of MI heart correlated positively with total or chymase-dependent AIIFA. Augmented AIIFA was also detected in the left atrium of post-MI hearts. Our results indicated that cardiac angiotensin II formation could be activated in the infarcted as well as in non-infarcted myocardium of the post-MI human heart.
Spectroscopic and electrochemical characterization of a Pr4+ imidophosphorane complex and the redox chemistry of Nd3+ and Dy3+ complexes (2022)

The molecular tetravalent oxidation state for praseodymium is observed in solution <i>via</i> oxidation of the anionic trivalent precursor [K][Pr<sup>3+</sup>(NP(1,2-bis-<sup><i>t</i></sup>Bu-diamidoethane)(NEt<sub>2</sub>))<sub>4</sub>] (1-Pr(NP*)) with AgI at -35 °C. The Pr<sup>4+</sup> complex is characterized in solution <i>via</i> cyclic voltammetry, UV-vis-NIR electronic absorption spectroscopy, and EPR spectroscopy. Electrochemical analyses of [K][Ln<sup>3+</sup>(NP(1,2-bis-<sup><i>t</i></sup>Bu-diamidoethane)(NEt<sub>2</sub>))<sub>4</sub>] (Ln = Nd and Dy) by cyclic voltammetry are reported and, in conjunction with theoretical modeling of electronic structure and oxidation potential, are indicative of principal ligand oxidations in contrast to the metal-centered oxidation observed for 1-Pr(NP*). The identification of a tetravalent praseodymium complex in <i>in situ</i> UV-vis and EPR experiments is further validated by theoretical modeling of the redox chemistry and the UV-vis spectrum. The latter study was performed by extended multistate pair-density functional theory (XMS-PDFT) and implicates a multiconfigurational ground state for the tetravalent praseodymium complex.
2-Chloroadenosine increases calcium mobilization from mouse calvaria in vitro (1982)

The effect of 2-chloroadenosine on bone resorption and on cyclic AMP formation in murine calvarial bones in vitro was investigated. 2-Chloroadenosine increased the release of 45Ca from the cultured bones, but had no effect on dead bones, indicating that the effect is cell mediated. The adenosine analogue remained in the medium for 48 h and caused a transient stimulation of the formation of cyclic AMP. The dose-response curve for the stimulatory effect on cyclic AMP accumulation was linear up to 10(-4) M. The dose-response curve for 45Ca release was liner from 3 x 10(-7) M to 3 x 10(-5) M but then showed a decline in the response. 8-Bromo cyclic AMP inhibited the release of 45Ca in 24 h cultures. The initial stimulatory effect on bone resorption by 2-chloroadenosine may therefore not depend on cyclic AMP. The level of inosine increased during culture indicating that adenosine is formed by bone tissue.
Omp35, a New Enterobacter aerogenes Porin Involved in Selective Susceptibility to Cephalosporins (2004)

In Enterobacter aerogenes, beta-lactam resistance often involves a decrease in outer membrane permeability induced by modifications of porin synthesis. In ATCC 15038 strain, we observed a different pattern of porin production associated with a variable antibiotic susceptibility. We purified Omp35, which is expressed under conditions of low osmolality and analyzed its pore-forming properties in artificial membranes. This porin was found to be an OmpF-like protein with high conductance values. It showed a noticeably higher conductance compared to Omp36 and a specific location of WNYT residues in the L3 loop. The importance of the constriction region in the porin function suggests that this organization is involved in the level of susceptibility to negative large cephalosporins such as ceftriaxone by bacteria producing the Omp35 porin subfamily.
Oxidative Stress Resistance inDeinococcus radiodurans (2011)

Deinococcus radiodurans is a robust bacterium best known for its capacity to repair massive DNA damage efficiently and accurately. It is extremely resistant to many DNA-damaging agents, including ionizing radiation and UV radiation (100 to 295 nm), desiccation, and mitomycin C, which induce oxidative damage not only to DNA but also to all cellular macromolecules via the production of reactive oxygen species. The extreme resilience of D. radiodurans to oxidative stress is imparted synergistically by an efficient protection of proteins against oxidative stress and an efficient DNA repair mechanism, enhanced by functional redundancies in both systems. D. radiodurans assets for the prevention of and recovery from oxidative stress are extensively reviewed here. Radiation- and desiccation-resistant bacteria such as D. radiodurans have substantially lower protein oxidation levels than do sensitive bacteria but have similar yields of DNA double-strand breaks. These findings challenge the concept of DNA as the primary target of radiation toxicity while advancing protein damage, and the protection of proteins against oxidative damage, as a new paradigm of radiation toxicity and survival. The protection of DNA repair and other proteins against oxidative damage is imparted by enzymatic and nonenzymatic antioxidant defense systems dominated by divalent manganese complexes. Given that oxidative stress caused by the accumulation of reactive oxygen species is associated with aging and cancer, a comprehensive outlook on D. radiodurans strategies of combating oxidative stress may open new avenues for antiaging and anticancer treatments. The study of the antioxidation protection in D. radiodurans is therefore of considerable potential interest for medicine and public health.
Ein mobiler und offener Kernspintomograph: Kernspintomographie für Medizin und Materialforschung (2005)

An der RWTH Aachen wurde der erste offene und mobile Kernspintomograph entwickelt. Anders als die normalerweise riesigen und unbeweglichen Geräte besitzt er keine enge Magnetröhre. So kann er auch in große Untersuchungsobjekte hinein schauen, ohne dass diese zerstört werden müssen. Wie eine Lupe erfasst er dabei ein begrenztes Volumen um den Aufsatzpunkt herum. Neben der Medizin ermöglicht der offene Tomograph viele neue Anwendungsgebiete, vor allem in der Materialprüfung und Qualitätskontrolle. Der Aachener Prototyp kann auch das Fließprofil und die Geschwindigkeitsverteilung strömender Flüssigkeiten sichtbar machen. Sein offenes Prinzip erforderte neue technische Komponenten und modifizierte bildgebende Verfahren. Die Messzeit pro Bild kann heute schon unter einer Viertelstunde liegen.
Epidemiology of cancer-associated venous thrombosis (2013)

Cancer-associated venous thrombosis is a common condition, although the reported incidence varies widely between studies depending on patient population, start and duration of follow-up, and the method of detecting and reporting thrombotic events. Furthermore, as cancer is a heterogeneous disease, the risk of venous thrombosis depends on cancer types and stages, treatment measures, and patient-related factors. In general, cancer patients with venous thrombosis do not fare well and have an increased mortality compared with cancer patients without. This may be explained by the more aggressive type of malignancies associated with this condition. It is hypothesized that thromboprophylaxis in cancer patients might improve prognosis and quality of life by preventing thrombotic events. However, anticoagulant treatment leads to increased bleeding, particularly in this patient group, so in case of proven benefit of thromboprophylaxis, only patients with a high risk of venous thrombosis should be considered. This review describes the literature on incidence of and risk factors for cancer-associated venous thrombosis, with the aim to provide a basis for identification of high-risk patients and for further development and refinement of prediction models. Furthermore, knowledge on risk factors for cancer-related venous thrombosis may enhance the understanding of the pathophysiology of thrombosis in these patients.
Measurement of the Inelastic Proton-Proton Cross Section at s=13  TeV with the ATLAS Detector at the LHC (2016)

This Letter presents a measurement of the inelastic proton-proton cross section using 60 μb^{-1} of pp collisions at a center-of-mass energy sqrt[s] of 13 TeV with the ATLAS detector at the LHC. Inelastic interactions are selected using rings of plastic scintillators in the forward region (2.07<|η|<3.86) of the detector. A cross section of 68.1±1.4 mb is measured in the fiducial region ξ=M_{X}^{2}/s>10^{-6}, where M_{X} is the larger invariant mass of the two hadronic systems separated by the largest rapidity gap in the event. In this ξ range the scintillators are highly efficient. For diffractive events this corresponds to cases where at least one proton dissociates to a system with M_{X}>13 GeV. The measured cross section is compared with a range of theoretical predictions. When extrapolated to the full phase space, a cross section of 78.1±2.9 mb is measured, consistent with the inelastic cross section increasing with center-of-mass energy.
Wave Propagation in a Nonlocal Strain-Softening Continuum (1992)

The problem of wave propagation in a nonlocal strain softening solid is first discussed analytically. It is demonstrated that 'loading' waves can still propagate in the strain softening regime, studying the admissible solutions of the equation of motion by a standard dispersion analysis. The error due to a discretization into finite elements is also derived in a one dimensional setting using the previous analytical result. The influence of the computation of nonlocal terms is illustrated.