gebhart/patrepeval huggingface dataset:
Applying Two-Stage Differential Evolution for Energy Saving in Optimal Chiller Loading (2019)

In Taiwan, over 45% of the energy in common buildings is used for the air-conditioning system. In particular, the chiller plant consumes about 70% of the energy in air-conditioning system. The electric energy consumption of air-condition system in a clean room of semiconductor factory is about 5–10 times of that in a common building. Consequently, the optimal chiller loading in energy saving of building is a vital issue. This paper develops a new algorithm to solve optimal chiller loading (OCL) problems. The proposed two-stage differential evolution algorithm integrated the advantages of exploration (global search) in the modified binary differential evolution (MBDE) algorithm and exploitation (local search) in the real-valued differential evolution (DE) algorithm for finding the optimal solution of OCL problems. In order to show the performance of the proposed algorithm, comparison with other optimization methods has been done and analyzed. The result shows that the proposed algorithm can obtain similar or better solution in comparison to previous studies. It is a promising approach for the OCL problem.
Erythrocytic Pyruvate Kinase Mutations Causing Hemolytic Anemia, Osteosclerosis, and Secondary Hemochromatosis in Dogs (2012)

Erythrocytic PK deficiency is caused by different mutations in different dog breeds and causes chronic severe hemolytic anemia, hemosiderosis, and secondary hemochromatosis because of chronic hemolysis and, an as yet unexplained osteosclerosis. The newly developed breed-specific mutation assays simplify the diagnosis of PK deficiency.
200 V Enhancement-Mode p-GaN HEMTs Fabricated on 200 mm GaN-on-SOI With Trench Isolation for Monolithic Integration (2017)

Monolithic integration of a half bridge on the same GaN-on-Si wafer is very challenging because the devices share a common conductive Si substrate. In this letter, we propose to use GaN-on-SOI (silicon-on-insulator) to isolate the devices by trench etching through the GaN/Si(111) layers and stopping in the SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> buried layer. By well-controlled epitaxy and device fabrication, high-performance 200 V enhancement-mode (e-mode) p-GaN high electron mobility transistors with a gate width of 36 mm are achieved. This letter demonstrates that by using GaN-on-SOI in combination with trench isolation, it is very promising to monolithically integrate GaN power systems on the same wafer to reduce the parasitic inductance and die size.
Hormone-sensitive lipase (2002)

Hormone-sensitive lipase (HSL) is an intracellular neutral lipase that is capable of hydrolyzing triacylglycerols, diacylglycerols, monoacylglycerols, and cholesteryl esters, as well as other lipid and water soluble substrates. HSL activity is regulated post-translationally by phosphorylation and also by pretranslational mechanisms. The enzyme is highly expressed in adipose tissue and steroidogenic tissues, with lower amounts expressed in cardiac and skeletal muscle, macrophages, and islets. Studies of the structure of HSL have identified several amino acids and regions of the molecule that are critical for enzymatic activity and regulation of HSL. This has led to important insights into its function, including the interaction of HSL with other intracellular proteins, such as adipocyte lipid binding protein. Accumulating evidence has defined important functions for HSL in normal physiology, affecting adipocyte lipolysis, steroidogenesis, spermatogenesis, and perhaps insulin secretion and insulin action; however, direct links between abnormal expression or genetic variations of HSL and human disorders, such as obesity, insulin resistance, type 2 diabetes, and hyperlipidemia, await further clarification. The published reports examining the regulation, and function of HSL in normal physiology and disease are reviewed in this paper.
Non-homogeneous Neumann problems in domains with small holes (1988)

avec les conditions gnrales d'utilisation (
The Alborada-I3A Corpus of Disordered Speech (2010)

This paper describes the “Alborada-I3A ” corpus of disordered speech, acquired during the recent years for the research in different speech technologies for the handicapped like Automatic Speech Recognition (ASR) or pronunciation assessment. It contains more than 2 hours of speech from 14 young impaired speakers and nearly 9 hours from 232 unimpaired age-matched peers whose collaboration was possible by the joint work with different educational and assistive institutions. Furthermore, some extra resources are provided with the corpus, including the results of a perceptual human-based labeling of the lexical mispronunciations made by the impaired speakers. The corpus has been used to achieve results in different tasks like analyses on the speech production in impaired children, acoustic and lexical adaptation for ASR and studies on the speech proficiency of the impaired speakers. Finally, the full corpus is freely available for the research community with the only restrictions of maintaining all its data and resources for research purposes only and keeping the privacy of the speakers and their speech data. 1.
Stopped-Flow Kinetics of Tetrazine Cycloadditions; Experimental and Computational Studies toward Sequential Transition States (2005)

The Diels-Alder cycloadditions of tetrazines (1) with alkynes (2) are expected to give bicyclic adducts (3). Kinetic measurements of the cycloadditions of 1a and 1b with 2a give DeltaG(++) = 19.2 +/- 1.0 and 11.5 +/- 1.2 kcal/mol, respectively. Stopped-flow UV studies on the reaction of 1b with 2a show an isosbestic point at 428 nm; this places an upper limit of 11.6 +/- 2.6 kcal/mol on DeltaG(++) for loss of N(2) from the putative bicyclic intermediate 3b. Calculations (B3LYP/6-31G(d,p) + ZPVE) of transition structures for the reaction of tetrazinediacid 1d with propynylamine 2c are consistent with the experimental results for the reaction of 1b with 2a. This and several related model systems reveal two interesting features of the calculated energy surfaces. First, there may be no barrier for the loss of nitrogen from structures 3 and thus there may be two sequential transition states. This also extends Berson's correlation of activation energy with reaction energy in pericyclic reactions to significantly lower barriers. Second, for the cycloaddition of 4e and 2c, there is neither an intermediate nor a transition state between TS3e and the final product 6e. It appears that the energy surface "turns a corner" in the vicinity of a structure resembling 5e. This is not a mathematically well-defined point but has chemical consequences in that the overall exothermicity of the reaction from 4e to 6e is not felt in TS3e.
Thermotropic Liquid Crystalline Character and Vesicular Properties of Some Functionalized Long-Chain Di-n-dodecyl Quaternary Ammonium Salts (1987)

Abstract In several reports it has been shown that amphiphilic molecules, including phospholipids, which aggregate in solution to form micelles, vesicles or liposomes also exhibit thermotropic liquid crystalline phases. In conjunction with our recent work on the synthesis and characterization of vesicle-forming monomeric and polymerized allyl and diallyl di-n-alkyl quarternary ammonium salts, a series of analogously functionalized derivatives has been prepared. Di-n-dodecyldimethyl quarternary ammonium bromide was employed as the parent compound. The new quarternary ammonium salts were formed by replacing one or both of the methyl groups in the parent compound by groups such as—CH2—CH=CH2,—CH2CH2OH,—CH2COOH,—CH2CH2COOH, or—CH2CH2CH2CN. The existence of liquid crystalline phases in these quarternaries was established by optical microscopy while transition temperatures as well as thermodynamic parameters were determined by DSC. Some of these compounds when dispersed in water and sonicated ultimately formed vesicles the structure of which was observed by electron microscopy. The effect of the various functional groups on the liquid crystalline phase behavior of these compounds exhibits a well defined variation. However, no systematic variation has been observed on the ability of these same functional groups to affect vesicles formation.
Study of the cytolethal distending toxin (CDT)‐activated cell cycle checkpoint (2001)

The bacterial cytolethal distending toxin (CDT) triggers a G2/M cell cycle arrest in eukaryotic cells by inhibiting the CDC25C phosphatase‐dependent CDK1 dephosphorylation and activation. We report that upon CDT treatment CDC25C is fully sequestered in the cytoplasmic compartment, an effect that is reminiscent of DNA damage‐dependent checkpoint activation. We show that the checkpoint kinase CHK2, an upstream regulator of CDC25C, is phosphorylated and activated after CDT treatment. In contrast to what is observed with other DNA damaging agents, we demonstrate that the activation of CHK2 can only take place during S‐phase. Use of wortmannin and caffeine suggests that this effect is not dependent on ATM but rather on another as yet unidentified PI3 kinase family member. These results confirm that the CDT is therefore responsible for specific genomic injuries that block cell proliferation by activating a cell cycle checkpoint.
Adaptive covariance estimation of locally stationary processes (1998)

It is shown that the covariance operator of a locally stationary process has approximate eigenvectors that are local cosine functions. We model locally stationary processes with pseudo-differential operators that are time-varying convolutions. An adaptive covariance estimation is calculated by searching first for a "best" local cosine basis which approximates the covariance by a band or a diagonal matrix. The estimation is obtained from regularized versions of the diagonal coefficients in the best basis.
Photocatalytic Degradation Characteristics of Different Organic Compounds at TiO2 Nanoporous Film Electrodes with Mixed Anatase/Rutile Phases (2006)

Nanoporous TiO2 film electrodes with a mixed anatase/ rutile phase were prepared by dip-coating TiO2 nanoparticle colloid onto Indium Tin Oxide (ITO) conducting glass substrates and a subsequent calcination process at 700 degrees C for 16 h. The photocatalytic oxidation of a wide range of organic compounds has been studied using the photoelectrochemical method under the conditions that the photohole capturing step controls the overall photocatalytic processes. The characteristics of the mixed anatase/ rutile phase TiO2 film electrodes were compared with pure anatase phase TiO2 film electrodes to identify the key differences between them. The results revealed that different organic compounds, despite their difference in chemical entities, can be stoichiometrically mineralized at the mixed-phase TiO2 electrode under diffusion-controlled conditions, which is in great contrast to the situation at the pure anatase phase TiO2 electrode. The exceptional ability of the mixed-phase TiO2 electrodes for mineralization of organic compounds and their remarkable resistance to the inhibition by aromatic compounds at higher concentration has been explained by the synergetic effect of the rutile and anatase phases. For this type of mixed phase electrodes, upon absorption of UV light, the electron-transfer pathway from anatase phase to rutile phase facilitates the separation of photoelectron and photohole, extending the lifetime of the photoelectron and photohole.
Printed Coupled-Fed PIFA for Seven-Band GSM/UMTS/LTE WWAN Mobile Phone (2012)

A planar printed PIFA is proposed and fabricated in this work, which is promising for internal mobile applications. In the design, the presented antenna consists of a feeding strip and a coupling strip (which is short-circuited to the system ground by a long shorting strip). By the coupled-fed excitation, the proposed antenna can generate multiple resonant modes at lower and upper bands for seven-band WWAN operation, covering GSM850/900/DCS1800/PCS1900/UMTS2100/LTE2300/2500. In detail, the feeding strip can excite high frequency current distributions on the coupling strip by a coupling gap to generate a fundamental resonant mode at around 800 MHz, while the desired upper resonant modes at about 1850 MHz and 2550 MHz can be achieved by the feeding strip itself. The proposed antenna occupies a size of 15 × 45 mm2 and is easily printed on one surface of a FR4 substrate as system circuit board, which makes it suitable for practical mobile applications. Finally, the simulated and measured results are given, which obtain good agreement and illuminate the reliability of the scheme.
Creating 3D models with uncalibrated cameras (2002)

We describe a factorization-based method to recover 3D models from multiple perspective views with uncalibrated cameras. The method first performs a projective reconstruction using a bilinear factorization algorithm, and then converts the projective solution to a Euclidean one by enforcing metric constraints. We present three factorization-based normalization algorithms to generate the Euclidean reconstruction and the intrinsic parameters, assuming zero skews. The first two algorithms are linear, one for dealing with the case that only the focal lengths are unknown, and another for the case that the focal lengths and the constant principal point are unknown. The third algorithm is bilinear dealing with the case that the focal lengths, the principal points and the aspect ratios are all unknown. We present the results of applying this method to building modeling, terrain recovery and multi-camera calibration.
Cannabinoids in the management of difficult to treat pain (2008)

Ethan B RussoGW Pharmaceuticals, Vashon, WA, USAAbstract: This article reviews recent research on cannabinoid analgesia via the endocannabinoid system and non-receptor mechanisms, as well as randomized clinical trials employing cannabinoids in pain treatment. Tetrahydrocannabinol (THC, Marinol&amp;amp;reg;) and nabilone (Cesamet&amp;amp;reg;) are currently approved in the United States and other countries, but not for pain indications. Other synthetic cannabinoids, such as ajulemic acid, are in development. Crude herbal cannabis remains illegal in most jurisdictions but is also under investigation. Sativex&amp;amp;reg;, a cannabis derived oromucosal spray containing equal proportions of THC (partial CB1 receptor agonist) and cannabidiol (CBD, a non-euphoriant, anti-inflammatory analgesic with CB1 receptor antagonist and endocannabinoid modulating effects) was approved in Canada in 2005 for treatment of central neuropathic pain in multiple sclerosis, and in 2007 for intractable cancer pain. Numerous randomized clinical trials have demonstrated safety and efficacy for Sativex in central and peripheral neuropathic pain, rheumatoid arthritis and cancer pain. An Investigational New Drug application to conduct advanced clinical trials for cancer pain was approved by the US FDA in January 2006. Cannabinoid analgesics have generally been well tolerated in clinical trials with acceptable adverse event profiles. Their adjunctive addition to the pharmacological armamentarium for treatment of pain shows great promise.Keywords: cannabinoids, tetrahydrocannabinol, cannabidiol, analgesia, pain management, multiple sclerosis
Optimising the therapy of exocrine pancreatic insufficiency by the association of a proton pump inhibitor to enteric coated pancreatic extracts: Figure 1 (2006)

conclusion, repeated stiffness assessment appears to be a good and safe alternative method of indicating antiviral combination therapy in PN-ALT patients reluctant to undergo liver biopsy.
Coarctation of the aorta and persistent left superior vena cava: HDlive Flow features at 14 weeks of gestation (2022)

To the best of our knowledge, this is the first report on HDlive Flow features of fetal CoA and PLSVC using STIC early in the second trimester of pregnancy.
Robust tracking control of robots by a linear feedback law (1991)

For the trajectory following problem of a robot manipulator, a simple linear robust fedback control law with constant gain matrix is proposed that makes the resulting error system uniformly ultimately bounded. This control law is very easy to implement by simply choosing a feedback gain according to the coefficients of a polynomial function of the tracking errors which is a bounding function for the terms in the Lagrange-Euler formulation. In the limit as the gain approaches infinity the error system becomes globally asymptotically stable.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Experimental Determination of Absolute Spectral Radiance and Emissivity of a Photonic Crystal Filament (2022)

A recent discovery of super-Planckian radiation in the far-field has attracted a great deal of interest in thermal radiation control using photonic crystals (PC) architecture. The finding is based on a careful comparison of radiation intensity emitted from a PC nano-filament and a blackbody at the same temperature and same wavelength at λ∼1.7 μm. Extending that finding, we determined the absolute spectral radiance of such a PC filament at λ∼1.7 μm at elevated temperature, T = 445–723 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> °</sup> K, and compared its value to that predicted by Planck's blackbody radiation law. Our data confirmed that the PC spectral radiance surpassed that of a blackbody by an order-of-magnitude. We also determined the spectral emissivity of our PC filament and showed that its value far exceeded unity at resonance and fell below unity away from resonance. The observation of non-equality between absorptivity and emissivity suggests that a strong optical non-reciprocity takes place in our PC nano-filament.
Functional Contact Lenses for Remote Health Monitoring in Developing Countries (2011)

The opportunities afforded by using a functional contact lens for remote wireless health status monitoring are discussed and the progress to date in the development of this technology platform is presented. A functional contact lens complete with sensors and embedded circuitry can be used to monitor the composition of tear fluid and, by extension, a number of health-status related parameters in the body in a noninvasive and continuous fashion. The data collected by the disposable contact lens may be sent wirelessly to a mobile phone that, in turn, can relay the information to a medical practitioner via the cellular phone network. If successfully developed and deployed, such a system can be used for monitoring a variety of health indicators over a large geographic area and population distribution with minimal need for the physical presence of health care providers.
Studies of NMDA Receptor Function and Stoichiometry with Truncated and Tandem Subunits (2003)

The subunits that compose eukaryotic glutamate ion channel receptors have three transmembrane domains (TMs) and terminate with intracellular tails that are important for controlling channel expression and localization. Truncation of NMDA receptor subunits before the final TM showed that this TM and intracellular tail region are necessary to form functional channels. However, it is shown here that these truncated subunits may be partially rescued by coexpressing the final TM and tail as a separate protein. The whole-cell currents so produced are somewhat lower than with full-length subunits, and they do not show the sag characteristic of currents from channels containing NR1 and NR2A subunits in the continued presence of an agonist. In addition, these truncated subunits were joined to full-length subunits to generate tandems. The functional expression of these tandems confirmed the tetrameric structure of NMDA receptors and also suggested that the subunits making up NMDA receptors are arranged as a dimer of dimers in the receptors with a 1-1-2-2 orientation of the subunits in the channel, and not in an alternating pattern of subunits around the pore. These results may redirect future studies into the mechanism of binding and gating in these receptors toward schemes including dimers, and may also be relevant to studies of glutamate receptor ion channels in general.
FoodSQRBlock: Digitizing food production & supply chain with blockchain & QR code in the cloud (2020)

&lt;div&gt;&lt;div&gt;&lt;div&gt;&lt;p&gt;Food safety is an important issue in today’s world. Traditional agri-food production system doesn’t offer easy traceability of the produce at any point of the supply chain, and hence, during a food-borne outbreak, it is very difficult to sift through food production data to track produce and origin of the outbreak. In recent years, blockchain based food production system has resolved this challenge, however, none of the proposed methodologies makes the food production data easily accessible, traceable and verifiable by consumers or producers using mobile/edge devices. In this paper, we propose FoodSQRBlock (Food Safety Quick Response Block), a blockchain technology based framework, which digitizes the food production information, and makes it easily accessible, traceable and verifiable by the consumers and producers by using QR codes. We also propose a large scale integration of FoodSQRBlock in the cloud to show the feasibility and scalability of the framework, and experimental evaluation to prove that.&lt;/p&gt;&lt;/div&gt;&lt;/div&gt;&lt;/div&gt;
Results of the OPC Evaluation Done within JCOP for the Control of the LHC Experiments (1999)

The construction of the LHC experiments’ control systems will require the integration of a wide range of COTS (Component Of The Shelf) and custom components: hardware such as instruments, controllers, fieldbuses and sensors as well as applications, for example, for operator control and visualization or for subsystems supervision. This integration may require a non-negligible effort if standard interfaces or integration mechanisms are not applied. OLE for Process Control (OPC) is a recently defined set of interfaces designed to allow Windows applications to access control data. OPC is based on Microsoft DCOM and is developed by the OPC foundation [1]. This paper presents the result of an evaluation done in the context of the Joint Controls Project (JCOP) [2]. The aim of this evaluation was to study the usability of OPC for the detector control of the LHC experiments. In particular it presents the benefit and limitations of the specifications, the availability of OPC compliant COTS and the usability of OPC development kits to develop applications accessing custom devices or non-Windows platforms.
Detection of Sentinel Lymph Nodes With Lymphazurin in Cervical, Uterine, and Vulvar Malignancies (1999)

In a limited number of patients, lymphazurin day may be useful in identifying or assessing the sentinel nodes draining vulvar and cervical cancers. The role of this procedure in treatment planning for patients with gynecologic malignancies is yet to be determined.