gebhart/patrepeval huggingface dataset:
The Prevalence of Hyperprolactinemia After Long-term Haloperidol Use in Patients With Chronic Schizophrenia (2005)

Jung, Do-Un MD; Seo, Young-Soo MD, PhD; Park, Jae-Hoon MD, PhD; Jeong, Chi-Young MD; Conley, Robert R. MD; Kelly, Deanna L. PharmD, BCPP; Shim, Joo-Cheol MD, PhD Author Information
Characterization of a Unique Coenzyme B6 Radical in the Ascarylose Biosynthetic Pathway (2000)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTCharacterization of a Unique Coenzyme B6 Radical in the Ascarylose Biosynthetic PathwayCheng-Wei T. Chang, David A. Johnson, Vahe Bandarian, Huiqiang Zhou, Russell LoBrutto, George H. Reed, and Hung-wen LiuView Author Information Department of Chemistry, University of Minnesota Minneapolis, Minnesota, 55455 The Institute for Enzyme Research, Graduate School and Department of Biochemistry College of Agricultural and Life Sciences University of Wisconsin, Madison, Wisconsin 53705 Department of Plant Biology Arizona State University, Tempe, Arizona Cite this: J. Am. Chem. Soc. 2000, 122, 17, 4239–4240Publication Date (Web):April 14, 2000Publication History Received6 January 2000Published online14 April 2000Published inissue 1 May 2000https://pubs.acs.org/doi/10.1021/ja0000807https://doi.org/10.1021/ja0000807rapid-communicationACS PublicationsCopyright © 2000 American Chemical SocietyRequest reuse permissionsArticle Views229Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Alkyls,Coupling reactions,Electron paramagnetic resonance spectroscopy,Flavins,Redox reactions Get e-Alerts
Weld depth control in fiber laser welding of thin metal sheets (2008)

Laser beam welding of electrical connections or sealing of casings are typical applications in the field of precision engineering. Controlling the shape of the welded connections is an important issue in this context. A common requirement is for example to achieve a specific welding depth in order not to damage functional layers or contaminate the inside of casings. The use of single mode fiber lasers in combination with scanning optics offers new opportunities regarding these needs. Spot welds for example can be replaced by ring welds, moving the laser beam on a circular path with multiple revolutions. Experiments revealed that depth and shape of such welds can be controlled very precisely when welding metal sheets thicker than 200 µm. Decreasing material thickness impedes this controllability with regard to thermal effects like heat accumulation. In this paper an approach for optimizing the spatial modulation parameters is introduced. In order to control depth and width of welds in metal sheets thinner than 200 µm experiments concerning variation of modulation type, welding time and focus diameter are presented. The experimental work is used to guide physical modeling simulations revealing a deeper understanding of the process.
Long-term organ culture of normal human bladder. (1983)

Normal adult human bladder obtained at cystoscopy has been maintained in long-term organ culture. Several media were tested for their ability to maintain viability and normal tissue morphology. The optimum medium was Ham's F-12 nutrient mixture, supplemented with 10% fetal calf serum, hydrocortisone (1 microgram/ml), and FeSO4, (0.45 microgram/ml). During the first 28 days in vitro, epithelial damage incurred at biopsy and during preparation of the cultures was repaired, and epithelialization of cut stromal surfaces occurred. A wave of cell proliferation was identified by [3H]thymidine autoradiography, 24-h labeling indices rising to a peak of up to 50% on the cut sides of the cultures between 7 and 21 days and falling to 0 to 5% by 21 to 28 days. The regenerating epithelium showed all the normal features of urothelial cell differentiation when examined by scanning and transmission electron microscopy. From 28 days, histology and scanning and transmission electron microscopy showed the cultured urothelium in most cultures to resemble closely that in the normal bladder in vivo, and in this mature state cultures were maintained for 100 days. Urothelium derived from certain patients, although showing normal surface maturation, developed enlarged intercellular spaces or intraepithelial mucin-containing acini. A study of the cytology of cells shed into the medium at different stages in culture showed that culture viability and epithelial differentiation could be monitored easily in long-term culture by this nondestructive means.
Self-Excited Vibrations of Reciprocating Compressor Plate Valves (1986)

The self-excitation mechanism causing the flutter of reciprocating compressor plate valves i s experimentally investigated under steady state cond itions. The relation between the plate oscillations an d the resulting pressure pulsations is established by means of simultaneous recording of the plate movement s and the upstream and downstream pressure pulsations. It is shown that movements of the valve pl ate produce fluid forces which are destabilizing because they are in phase with the velocity of the plat e. Thus, acoustic resonances of the piping system a re strongly excited due to their cqupling with the vib ration of the v~lve plate. The stiffness of the valve sp rings has been found to have very little influence o n the vibration frequency which is controlled by the system acoustical resonances. \V'hilst the system oscillation is sustained , the valve plate stays parallel to the seat, bu t substantial plate tilting eliminates this vibration. T hus, the valve vibrations can be eliminated by usin g unevenly distributed springs which force the valve plate to tilt while opening. 1. INT)'WDUCTION Self-excited vibrations of spring loaded c ompressor valves are sustained via a destabilizin g fluid force which increases as the valve lift is increased. Several iqvestigations have characterized experimentally (1, 2) and theoretically (3, 4) this destabilizing fluid force as a force (or a pressure ) coefficient
Oil Lenses on Water and the Nature of Monomolecular Expanded Films (1933)

A higher hydrocarbon, such as tetradecane, on the surface of water forms a circular lens. The condition for the formation of such stable lenses is that the spreading coefficient FS = γ1 — γ2 — γ12 shall be negative. As the volume of the oil lens is increased, the thickness t at the center slowly approaches a limiting value given by t∞2 = —2Fsρ1/gρ2(ρ1 — ρ2). Equations are given by which FS can be accurately determined from measurements of the radii of large lenses of known volume. The magnitude of the linear tension at the lens boundary is also calculated. Experiments with tetradecane on water at 25°C give FS = —6.2 dynes cm—1 and γ = 26.9. When hydrophilic molecules are introduced into the interface between the lens and the water, they give a spreading force F12 which causes a decrease in — FS and in t. When t&amp;lt;0.1 mm gravitational effects are negligible and the lens degenerates into a duplex film. If such a film is confined by a movable barrier (piston), the force per unit length F exerted on the barrier is equal to FS. If the adsorbed molecules at the interface give a force F12 in accord with the gas laws, then (F — F0)(a — a0) = kT gives the equation of state of the duplex film, where F0 is the value of FS in the absence of hydrophilic substances. It is shown that this equation applies to expanded oil films on water and that these are properly regarded as duplex films although they are monomolecular. The presence of a kink in the observed F — a curves is attributed to the sudden appearance of micelles, each containing β-molecules when F12 rises to a critical value. For the fatty acids on dilute HCl, β = 13. This small value is due to the crowding apart of the heads because of hydration. The esters show little or no hydration and β = 60. The heat of formation of the micelles in the fatty acids is found to be 5.5+0.24n kg cal. per mole where n is the number of carbon atoms. The values of F0 and a0 for various substances are determined from data given by Adam.
Validation of electron beam position monitoring probes by comparison of dose profile measurements with beam displacement sensing in the microwave range (2011)

The development of a beam position monitoring and control architecture for compact linear accelerators requires novel sensors which fulfill the tight space restrictions given in such systems. This paper presents simulation and experimental data of capacitive pickup probes with high sensitivity capable of sensing beam deflections far below 1 mm and compact enough to be integrated in accelerating structures. The correlation of beam position monitoring output signals with dose profile measurements is presented indicating that the proposed compact sensors together with dedicated BPM hardware allow reliable electron beam trajectory determination.
Seamless Integration of Heterogeneous Devices and Access Control in Smart Homes (2012)

The recent trend of ubiquitous access to embedded physical devices over the Internet as well as increasing penetration of wireless protocols such as ZigBee has raised attention to smart homes. These systems consist of sensors, devices and smart appliances that can be monitored and controlled remotely by human users and cloud services. However, the lack of a de facto communication standard for smart homes creates a barrier against the interoperability of devices from different vendors. We address this challenge by proposing a holistic, extensible software architecture that seamlessly integrates heterogeneous protocol- and vendor-specific devices and services, while making these services securely available over the Internet. Our architecture is developed on top of the OSGi framework and incorporates a semantic model of a smart home system. As a result, we achieve semantic interoperability - the ability to integrate new applications and drivers into the deployed system during runtime. Furthermore, we integrate a new access control model for specific smart home scenarios. As a proof of our concept, we demonstrate the seamless semantic discovery of home devices at runtime by integrating several protocols including X10, Insteon, ZigBee and UPnP into a real test. Using smart phones and cloud services together with our home gateway implementation, we further demonstrate the ease of integration of new applications and drivers.
Einführung (1993)

In den letzten Jahrzehnten hat sich das Spektrum von Beschwerden und Krankheiten in allen Altersgruppen deutlich verschoben. Waren noch im 19. Jahrhundert akute lebensbedrohende und meist ansteckende Krankheiten die hauptsächlichen Todesursachen, — um 1900 bestimmten noch Grippe, Lungenentzündung und Mangelkrankheiten die Mortalitätsraten — so sind dies heute vor allem Herz-Kreislauf-Erkrankungen, Krebskrankheiten, andere chronische Leiden und Unfälle (Bundesminister für Jugend, Familie, Frauen und Gesundheit 1989).
Soziodemographische Faktoren und kontrollierter Interventionseffekt einer evidenzbasierten Patienteninformation zu Blutzuckertest und Primärprävention des Diabetes mellitus Typ 2 – gibt es Wechselwirkungen? (2014)

Hintergrund und Fragestellung: Das Wissen zu Primärprävention des Diabetes wurde durch evidenzbasierte (EBPI) im Vergleich zu Standard-Patienteninformationen signifikant erhöht. Untersucht wurde der Zusammenhang der soziodemographischen Faktoren (SES) mit dem Interventionseffekt auf das Wissen.
Mutant Strains of Escherichia coli K-12 Unable to Form Ubiquinone (1968)

A strain of Escherichia coli was isolated which was unable to form ubiquinone. This mutant was obtained by selecting strains unable to grow on malate as sole source of carbon. Such strains were further screened by examination of the quinone content of cells grown on a glucose medium. A mutant unable to form vitamin K was also isolated by this procedure. A genetic analysis of the ubiquinoneless strain showed that it possessed two mutations affecting ubiquinone biosynthesis.
Recent Progress in Structure Activity Relationship and Mechanistic Studies of Taxol Analogues (2005)

Structure activity relationship (SAR) and mechanism of paclitaxel and its analogues in recent years are discussed in the following areas: SAR of paclitaxel analogues toward "normal" and multi-drug resistance tumors; paclitaxel prodrugs with improved water solubitily and specificity; mechanism of paclitaxel related to tubulin binding and quest for its pharmacophore.
Heteroatom Tracing Reveals the 30-Atom Au–Ag Bimetallic Nanocluster as a Dimeric Structure (2020)

Understanding the formation of face-centered cubic (fcc) nanostructures at the atomic level remains a major task. With atomically precise nanoclusters (NCs) as model systems, herein we devised an atom-tracing strategy by heteroatom doping into Au<sub>30</sub>(SR)<sub>18</sub> (SR = S-<sup><i>t</i></sup>C<sub>4</sub>H<sub>9</sub>) to label the specific positions in M<sub>30</sub>(SR)<sub>18</sub> NCs (M = Au/Ag), which clearly reveals the dimeric nature of M<sub>30</sub>. Interestingly, the specific position is also consistent with the Ag-doping site in M<sub>21</sub>(SR)<sub>15</sub>. Electronic orbital analysis shows intrinsic orbital localization at the two specific positions in M<sub>30</sub>, which are decisive to the electronic structure of M<sub>30</sub>, regardless of Au or Ag occupancy. The fcc dimeric NC, which would not be discovered without Ag tracing, provides a possible explanation for the wide accessibility of nonsuperatomic Au-SR NCs.
Individuelle somatische Klassifikation von Neugeborenen auf der Grundlage von Körperhöhe und Körpergewicht der Mutter (Ergebnisse einer Validierungsstudie) (2022)

IBWP consider the maternal size for estimation of the fetal growth potential and achieve expected SGA- and LGA-rates of 10%. Consideration of individual growth potential avoids underestimation and overestimation of SGA- and LGA-rates. It aided analyses of birth weight with IBWP simplify the assessment of the nutritional status.
Aluminum spiking at contact windows in Al/Ti-W/Si (1988)

Aluminum spike formation through a Ti-W interdiffusion barrier layer at contact windows is studied by cross-sectional transmission electron microscopy for Al-1% Si and Al-2% Cu films. For Ti-W layers thinner than 1000 Å Al spikes form in both Al-Si and Al-Cu systems. The two types of Al films behave similarly in terms of the propensity for spike formation and spike morphology in the presence of a Ti-W layer. Aluminum spikes generally have an inverted pyramidal, truncated inverted pyramidal, or parallelepipedal shape. Aluminum in a spike is generally single crystal and some of the Al spikes maintain one of the following orientation relationships with the surrounding Si substrate: [011]Al∥[1̄23]Si and (200)Al∥(11̄1)Si or [001]Al∥[1̄12]Si and (200)Al is 2° off (11̄1)Si. A mechanism for Al spike formation through Ti-W is proposed.
Digitalización: hacia el infinito y más allá (2010)

A raiz de las jornadas El sector de la exhibicion independiente y los retos de la digitalizacion, celebradas en Barcelona entre el 4 y el 6 de marzo y organizadas por el ICAA, el autor reflexiona sobre los retos, posibilidades y objetivos, actuales, del cine digital.
The complexity of stoquastic local Hamiltonian problems (2008)

We study the complexity of the Local Hamiltonian Problem (denoted as LH-MIN) in the special case when a Hamiltonian obeys the condition that all off-diagonal matrix elements in the standard basis are real and non-positive. We will call such Hamiltonians, which are common in the natural world, stoquastic. An equivalent characterization of stoquastic Hamiltonians is that they have an entry-wise non-negative Gibbs density matrix for any temperature. We prove that LH-MIN for stoquastic Hamiltonians belongs to the complexity class AM -- a probabilistic version of NP with two rounds of communication between the prover and the verifier. We also show that 2-local stoquastic LH-MIN is hard for the class MA. With the additional promise of having a polynomial spectral gap, we show that stoquastic LH-MIN belongs to the class PostBPP=BPPpath--a generalization of BPP in which a post-selective readout is allowed. This last result also shows that any problem solved by adiabatic quantum computation using stoquastic Hamiltonians is in PostBPP.
Effect of Nanocrystal Size and Carbon on Grain Growth during Annealing of Copper Zinc Tin Sulfide Nanocrystal Coatings (2017)

Polycrystalline films were prepared by annealing coatings cast from colloidal dispersions of Cu2ZnSnS4 (CZTS) nanocrystals in sulfur vapor. This nanocrystal dispersion-based route is a promising potential low-cost approach for production of low-cost thin-film solar cells. We studied the effects of nanocrystal size, sulfur pressure, and carbon concentration on the microstructure development and grain growth during annealing. Coatings prepared from dispersions of CZTS nanocrystals with an average diameter of either 5 or 35 nm were annealed for 10–60 min at 600 °C in 50 or 500 Torr of sulfur. The CZTS nanocrystal size influenced both the rate and mechanism of grain growth. When coatings composed of 5 nm nanocrystals are annealed, abnormal grain growth forms micrometer-scale CZTS grains on the surface of the coating. In contrast, when CZTS coatings composed of 35 nm nanocrystals are annealed, grains grow uniformly via normal grain growth. Grain growth rates increased with sulfur pressure regardless of the nanocrystal size. The presence of carbon, originating from ligands used to stabilize nanocrystal dispersions, enhances abnormal grain growth, but too much carbon eventually inhibits all grain growth. On the basis of these observations, we propose a mechanism for microstructure development during annealing of CZTS nanocrystal coatings in sulfur. While much research effort has been expended on the reduction of carbon from nanocrystal coatings prior to sulfidation or selenization by means of ligand exchange or preannealing treatments in the belief that reduced carbon concentration aids CZTS microstructure development and solar cell efficiencies, this work indicates that carbon plays a more complex and significant role in CZTS grain growth than previously assumed: carbon may be beneficial or even required for rapid grain growth during sulfidation.
Growth restriction of an experimental live attenuated human parainfluenza virus type 2 vaccine in human ciliated airway epithelium in vitro parallels attenuation in African green monkeys (2020)

Human parainfluenza viruses (HPIVs) are common causes of severe pediatric respiratory viral disease. We characterized wild-type HPIV2 infection in an in vitro model of human airway epithelium (HAE) and found that the virus replicates to high titer, sheds apically, targets ciliated cells, and induces minimal cytopathology. Replication of an experimental, live attenuated HPIV2 vaccine strain, containing both temperature sensitive (ts) and non-ts attenuating mutations, was restricted >30-fold compared to rHPIV2-WT in HAE at 32°C and exhibited little productive replication at 37°C. This restriction paralleled attenuation in the upper and lower respiratory tract of African green monkeys, supporting the HAE model as an appropriate and convenient system for characterizing HPIV2 vaccine candidates.
Surfactant Surface Tension Effects on Promoting Hydrate Formation: An Experimental Study Using Fluorocarbon Surfactant (Intechem-01) + SDS Composite Surfactant (2013)

The investigation of surface tension is a very important task for gas hydrate studying. Surfactants can effectively reduce the surface tension, improve the gas storage capability of hydrate and increase the formation rate, shorten the induction time. The objective of this study were to obtain a better understanding of the role of surface tension on hydrate formation and build gas hydrate models involve surfactant. In this study it was highlighted that the surface tension of Intechem-01 + SDS composite surfactants in natural gas hydrate promotion system and the change rules at different temperatures, concentration and proportion. According to the results of experiment, the surface tension of composite surfactants decreased with the increase of Intechem-01. The best cooperating effect was observed in proportion (Intechem-01 content) of 0.6 - 0.7, where the surface tension was the lowest. In this proportion range, the composite surfactants showed the same effect to pure fluorine carbon surfactant. The study shown the surface tension of composite surfactants decreased with the rise of temperature, and they were in a linear relationship within a certain range. Surface tension of composite surfactants decreased with the increase of surfactant concentration, however, it was no longer decreased above critical micelle concentration (CMC). The fitting equation of surface tension with various factors has been obtained.
L'endothéline : pharmacologie cardiovasculaire et considérations physio-pathologiques (1996)

Les progres dans la connaissance du systeme des endothelines, puissants peptides vasomoteurs produits par l'endothelium vasculaire, ont ete spectaculaires, depuis leur biosynthese grâce a l'enzyme de conversion de l'endotheline (ECE), jusqu'a la pharmacologie de leurs recepteurs, ET A et ET B . La presence d'activites enzymatiques distinctes de l'ECE specifiques de certains organes fait envisager le developpement d'inhibiteurs selectifs. Les recepteurs sur les cellules musculaires lisses vasculaires et sur les cellules endotheliales relaient, respectivement, des actions vasoconstrictrices (surtout ET A ) et vasodilatatrices (essentiellement ET B ). L'etude de la contribution des endothelines a la regulation du systeme cardiovasculaire et a l'etiologie de certaines affections vasculaires est l'objet d'une forte competition car ces mises a jour pourraient conduire au developpement d'agents therapeutiques efficaces.
The Influence Of Incorporating Cobalt (Co) And Indium (In) Co-dopants On The Structural And Optical properties Of ZnO Nanoparticles (2016)

Co and In co-doped nanopowders of ZnO as well as In and Co singly doped ZnO were successfully prepared using sol-gel method. The synthesized samples were characterized using x-ray diffraction (XRD), UV-vis spectroscopy (UV-vis), Raman spectroscopy (RS), Transmission Electron Microscopy (TEM) and Energy Dispersive Spectroscopy (EDS). The effects of In and Co co-doping on the structural and optical properties were investigated. XRD results showed no peaks associated with In 3+ or Co 2+ ions indicating that In 3+ and Co 2+ ions substituted for Zn 2+ ions in the ZnO wurtzite structure, this was corroborated by the EDS results. Doping ZnO nanoparticles with In and Co significantly reduced the grain sizes whereas the lattice parameters were not significantly affected. TEM results confirmed that the nanoparticles were spherically shaped. Raman spectroscopy also confirmed that the ZnO nanoparticles were of a wurtzite hexagonal structure. Single doping reduced the energy band gaps and co-doping reduced them even further.