gebhart/patrepeval huggingface dataset:
High Dose Methyl Prednisolone in Refractory Chronic Lymphocytic Leukaemia (1999)

We treated 14 patients with advanced, resistant chronic lymphocytic leukaemia (CLL) including three with >10% prolymphocytes (CLL/PL) with high dose methyl prednisolone (HDMP). All patients had stage C CLL or bulky stage B disease. There were 11 males and 3 females with a median age of 58.5 years (range: 49-69). Six out of eleven CLL patients had a partial response as defined by the NCI guidelines, no patient had a complete remission. The mean duration of PR was 19.6 months with a median of 8 months (range 6-78). Seven patients have died including the 5 non-responders. None of the 3 patients with CLL/PL had a measurable response. Previous treatments included chlorambucil, fludarabine, deoxycoformycin, anthracycline containing regimens such as CHOP and Campath-1H. HDMP was given at a dose of 1 g/m2 for five days, at monthly intervals for one to seven courses depending on the response. H2 antagonists and antimicrobial prophylaxis were given concurrently. Acyclovir prophylaxis was given if there was a recent history of herpes infection. HDMP was generally well tolerated. Side effects included fluid retention, hyperglycaemia, bradycardia (1 patient), herpes simplex (1), and pneumonia (1) in a patient with a previous history of recurrent chest infection and pneumonia. These results suggest that HDMP may be beneficial in the treatment of refractory CLL but is of no value in CLL/PL.
Target detection using orthogonal netted radar system (ONRS) (2007)

An orthogonal netted radar system (ONRS) is a networked system consisting of multiple radars, each of which uses an orthogonal set of coding waveforms, and operating at the same carrier frequency. ONRS can simultaneously operate in a monostatic and a multistatic mode, and thus possesses the advantages offered by both a monostatic and a multistatic radar system. The principles and structure of ONRS are described in this paper. The detection schemes using ONRS and an initial performance analysis is carried out. (4 pages)
PREVALÊNCIA DE MASTITE EM BOVINOS LEITEIROS: IFSULDEMINAS – CÂMPUS MUZAMBINHO (2015)

Mastite e prejudicial a pecuaria leiteira. O objetivo foi estudar a mastite por meio de registros em 20 anos. Fez-se testes de mastite, coletou-se leite das doentes e fez-se exames. Usou-se o Programa Excel para etiologia e moda para antibiograma. No periodo, verificou-se Staphylococcus , Streptococcus e Corynebacterium , maior sensibilidade a cura e mais glândulas mamarias sadias. Conhecer as causas de mastites, seus tratamentos e capacitar funcionarios sao essenciais para o sucesso da atividade.
A Vinylogous Donor in an Iron(III)-Catalysed Michael Reaction and an Enone–Dienol Tautomerism (1998)

A double acceptor-activated cycloalkene 1 reacts in an FeCl3 · 6 H2O catalysed Michael reaction surprisingly as a donor. The constitution of the product 2 results from a reaction of 1 in the γ-position, thus the Michael reaction is vinylogous with respect to the donor. A tautomerism between the enone 1 and the dienol 4 is found to be a precondition for this reactivity.
Fresnel diffraction on the edge of causality (2000)

Taking advantage of the slow optical response of low-temperature rare earth ion-doped crystal, we explore the similarity between causality and Fresnel diffraction by a straight edge. We relate these features to spectral resolution and selectivity. The concept is illustrated with experimental data.
Machine Learning Approach to Detect Arc Faults Based on Regular Coupling Features (2022)

During ac series arc faults (SAFs), arcing current features can change significantly or vanish rapidly under different load-combination modes and fault inception points. The phenomena make it very challenging for feature-extracting algorithms to detect SAFs. To address the issues, this article presents a detection model based on regular coupling features (RCFs). After the model is only trained by the samples in single-load circuits, it can detect SAFs under unknown multiload circuits. To extract the RCFs, asymmetric magnetic flux is coupled by passing the live line and the neutral line through the current transformer. The coupling signals are not influenced by the multiload circuits. According to the unique signals, two time-domain features and one frequency-domain feature are extracted to represent the RCFs, including impulse-factor analysis, covariance-matrix analysis, and multiple frequency-band analysis. Then, the impulse factor and its threshold are used to preprocess the signals and decrease analysis complexity for the classifier. Finally, the experimental results show that the proposed method has significantly improved generalization ability and detection accuracy in SAF detection.
Influence of Gravity and Ambient Pressure on Combustion and Flammability of n-Heptane and 1-Propanol Droplets in Air-Diluent Environments (2011)

Reduced gravity and normal gravity combustion experiments were performed with individual fiber-supported n-heptane and 1-propanol droplets with initial diameters in the 1-mm size range. Experiments were performed with air-inert mixtures at 0.1 MPa or 0.3 MPa and about 298 K, where helium, carbon dioxide, or xenon were separately used as inerts. The amount of inert gas required to suppress combustion was generally higher in reduced gravity than normal gravity, and higher mole fractions of xenon were required for suppression of combustion relative to helium or carbon dioxide. Helium was found to perform the best as a flame suppressant on a mass basis, i.e., mass fractions of helium required to suppress combustion were significantly smaller than for the other inert gases. Increasing the amount of inert gas generally decreased burning rates. Results indicate that ambient gas transport properties and the fuel type play an important role in determining flammability and combustion behaviors of the droplets. Comparison with cup burner results also show that gas transport properties influence flammabilities much more strongly for droplets than for cup burners.
Holographic beam samplers for high power laser (1992)

Smart laser-based material processing systems require complete monitoring of the laser beam characteristics. The development of such monitoring units depends strongly on the beam sampling device employed. Beam samplers compatible with a randomly polarized 1 kW average power Nd:YAG laser has been realized by etching an holographic grating directly onto the surface of a high quality fused silica substrate [1].
Crossed immunoelectrophoresis of human platelet membranes. Effect of charge on association and dissociation of the glycoprotein GPIIb-GPIIIa membrane complex. (1986)

The mechanism of association of the human platelet membrane GPIIb-GPIIIa-Ca2+ complex was studied by treating solubilized membranes with various enzymes and cationic peptides and by studying the binding of 45Ca2+ and 125I-fibrinogen before and after dissociation with EGTA and association with Ca2+. Neuraminidase shifted the complex cathodally (presumably due to cleavage of negatively charged domains), whereas trypsin had no such effect. The EGTA-dissociated complex was almost completely reassociated with neuraminidase or the cationic peptide, tetralysine. The monoclonal antibody 10E5, which specifically binds to the Ca2+-associated complex (not to its dissociated components), also bound to the neuraminidase-associated complex. Thus, Ca2+ is not necessary for the association of the complex. Neuraminidase treatment of washed intact platelets resulted in a cathodal shift of the membrane Triton X-100-extracted associated complex with no effect on its ability to dissociate in the presence of EGTA. Neuraminidase treatment of ADP-perturbed washed platelets also resulted in a cathodal shift of the associated complex; however, dissociation with EGTA was inhibited. Thus, critical neuraminidase-sensitive components of the complex (sialic acid residues) are not exposed on the surface of the platelet membrane of resting platelets, but do become accessible following platelet stimulation with ADP or membrane solubilization with Triton X-100. 45Ca2+ bound to the associated complex, to GPIIb of the dissociated complex (not to GPIIIa), to the Ca2+-reassociated complex, and to the neuraminidase-associated complex which had been dissociated with EGTA. Thus, neuraminidase-sensitive components of the solubilized membrane are not required for Ca2+ binding. 125I-fibrinogen bound to the associated complex (not the dissociated complex), to the Ca2+-reassociated complex, and to the neuraminidase-reassociated complex which had been dissociated with EGTA. Thus, Ca2+ is not necessary for 125I-fibrinogen binding to the major antigen complex.
Postprandial glucagon-like peptide-1 secretion is increased during the progression of glucose intolerance and obesity in high-fat/high-sucrose diet-fed rats (2015)

Glucagon-like peptide-1 (GLP-1) is secreted by distal enteroendocrine cells in response to luminal nutrients, and exerts insulinotropic and anorexigenic effects. Although GLP-1 secretory responses under established obese or diabetic conditions have been studied, it has not been investigated whether or how postprandial GLP-1 responses were affected during the progression of diet-induced obesity. In the present study, a meal tolerance test was performed every week in rats fed a high-fat and high-sucrose (HF/HS) diet to evaluate postprandial glycaemic, insulin and GLP-1 responses. In addition, gastric emptying was assessed by the acetaminophen method. After 8 weeks of HF/HS treatment, portal vein and intestinal mucosa were collected to examine GLP-1 production. Postprandial glucose in response to normal meal ingestion was increased in the HF/HS group within 2 weeks, and its elevation gradually returned close to that of the control group until day 50. Slower postprandial gastric emptying was observed in the HF/HS group on days 6, 13 and 34. Postprandial GLP-1 and insulin responses were increased in the HF/HS group at 7 weeks. Higher portal GLP-1 and insulin levels were observed in the HF/HS group, but mucosal gut hormone mRNA levels were unchanged. These results revealed that the postprandial GLP-1 response to meal ingestion is enhanced during the progression of diet-induced glucose intolerance and obesity in rats. The boosted postprandial GLP-1 secretion by chronic HF/HS diet treatment suggests increased sensitivity to luminal nutrients in the gut, and this may slow the establishment of glucose intolerance and obesity.
Rejection of Doppler shifted multipaths in airborne passive radar (2015)

In this article, we consider the problem of rejecting multipath ground echoes in airborne passive radar. In such an application, these multipath echoes present some Doppler-shift due to the movement of the airborne platform. Classic rejection methods with rejection mask sampled at the cell resolution in delay and Doppler lead to strong sidelobe residue that tend to mask the target responses. We propose here first to oversample this mask, solving the projection problem induced using the Moore-Penrose pseudo-inverse. This solution however requires the knowledge of the right oversampling factor necessary to get good rejection performance. We thus propose a different approach that permits to perform rejection over a continuous set, thus insuring good rejection. This solution provides some insight on the dimensionality of the subspace spanned by this continuous set, which can in turn be used to properly choose the oversampling factor. Simulations are provided for rejection on a Doppler interval, and in the context of airborne passive radar dealing with range and Doppler.
IMMA-Intelligently Moving Manikin - Project status (2010)

Automatic path plmming, i.e. the methodology to automatically find collision free motion patterns of objects being moved in space, is a well established research area and there are a number of distinguished groups in the world. Complete algorithms are of little industrial relevance due to the complexity of the problem (Canny, 1988). Instead, sampling based techniques, trading completeness for speed and simplicity, are typically the methods of choice. Common for these methods are the needs for efficient collision detection, nearest neighbour searching, graph searching and graph representation. The two most popular methods are: Probabilistic Roadmap Methods (PRM) (Bohlin and Kavraki, 2000) and Rapidly-Exploring Random Trees (RRT) (LaValle and Kuffuer, 1999). There are commercial available path planner tools, e.g. from Fraunhofer-Chalmers Centre (FCC) and KineoCam, on the market today that investigate if a part without any external support can find a collision free way from a starting position outside the assembly to its end position in the assembly structure. FCC has, inspired by both these probabilistic methods, developed a novel deterministic path planning algorithm. Path planning tools give valuable support when evaluating new product or workstation concepts and when comparing alternative solutions. Also different assembly sequences can be compared and verified.
Application of bacteria in concrete: a critical evaluation of the current status (2016)

Microbially induced carbonate precipitation has been tested over more than a decade as a technique to enhance concrete properties. Mainly bacteria following the pathways of urea decomposition, oxidation of organic acids, or nitrate reduction have been studied for this purpose. For bacteria mixed into fresh concrete, it is difficult to prove that they actively contribute to calcium carbonate precipitation and the effects on concrete strength are variable. Application of bacteria for surface consolidation has been shown to reduce water absorption and increase durability. Microbial self-healing of cracks in concrete shows promising results at the laboratory scale. Especially the use of self-protected mixed cultures opens perspectives for practical application. However, their self-healing efficiency needs to be further proven in larger concrete elements, and under non-ideal conditions. The use of denitrifying cultures for concurrent self-healing and production of corrosion inhibiting nitrites is a promising new strategy.
Bacterial volatiles elicit differential olfactory responses in insect species from the same and different trophic levels (2023)

Insect communities consist of species from several trophic levels that have to forage for suitable resources among and within larger patches of nonresources. To locate their resources, insects use diverse stimuli, including olfactory, visual, acoustic, tactile and gustatory cues. While most research has focused on cues derived from plants and other insects, there is mounting evidence that insects also respond to volatile organic compounds (VOCs) emitted by microorganisms. However, to date little is known about how the olfactory response of insects within and across different trophic levels is affected by bacterial VOCs. In this study, we used Y-tube bioassays and chemical analysis of VOCs to assess how VOCs emitted by bacteria affect the olfactory response of insects of the same and different trophic levels. Experiments were performed using two aphid species (Amphorophora idaei Börner and Myzus persicae var. nicotianae Blackman), three primary parasitoid species (Aphidius colemani Viereck, A. ervi Haliday, and A. matricariae Viereck), and two hyperparasitoid species (Asaphes suspensus Nees and Dendrocerus aphidum Rondani). Olfactory responses were evaluated for three bacterial strains (Bacillus pumilus ST18.16/133, Curtobacterium sp. ST18.16/085, and Staphylococcus saprophyticus ST18.16/160) that were isolated from the habitat of the insects. Results revealed that insects from all trophic levels responded to bacterial volatiles, but olfactory responses varied between and within trophic levels. All bacteria produced the same set of volatile compounds, but often in different relative concentrations. For 11 of these volatiles we found contrasting correlations between their concentration and the behavior of the primary parasitoids and hyperparasitoids. Furthermore, olfactometer experiments on three of these compounds confirmed the contrasting olfactory responses of primary parasitoids and hyperparasitoids. The potential of these findings for the development of novel semiochemical-based strategies to improve biological aphid control has been discussed.
Food Preference and Feeding Behavior of the German Cockroach, Blattella germanica (Linnaeus) (2006)

ABSTRACT: The purpose of this experiment was to study the food that male and female German cockroaches preferred and their feeding behavior. These 48-h-starved cockroaches were given choices among eight food items (four carbohydrate–rich foods: bread, sugar, banana, and potato; and four protein-rich foods: peanut, cheese, pork, and cat food). Modified eight-chamber olfactometers were used for this food preference experiment. Each kind of food was placed in each chamber of the olfactometer with 15 of each sex of the starving cockroaches placed at the center. The olfactometers were observed for 48 hours in the laboratory. The
Statistical analysis of PET radiomic features and metabolomic data: prediction of triple-negative breast cancer (2018)

International audience
Scoping studies - photon and low energy neutron interrogation (1997)

High energy photon interrogation of waste containers, with the aim of producing photo nuclear reactions, in specific materials, holds the potential of good penetration and rapid analysis. Compact high energy ({le} 10 MeV) photon sources in the form of electron linacs producing bremstrahlung radiation are readily available. Work with the Varitron variable energy accelerator at ISU will be described. Advantages and limitations of the technique will be discussed. Using positive ion induced neutron producing reactions, it is possible to generate neutrons in a specific energy range. By this means, variable penetration and specific reactions can be excited in the assayed material. Examples using the {sup 3}H(p,n) and {sup 7}Li(p,n) reactions as neutron sources will be discussed. 4 refs., 7 figs.
Adult patients with supratentorial pilocytic astrocytoma: long-term follow-up of prospective multicenter clinical trial NCCTG-867251 (Alliance) (2015)

The long-term follow-up results of this prospective trial confirm that adults with pilocytic astrocytomas have a favorable prognosis with regard to survival and neurologic function. Close observation is recommended for adults with pilocytic astrocytomas, reserving RT for salvage, as the majority remain stable after gross or subtotal resection and no adjuvant therapy.
RNA and protein synthesis in human peripheral blood polymorphonuclear leukocytes. (1979)

Polymorphonuclear leukocytes purified from human peripheral blood synthesized RNA and proteins when placed in cell culture. Autoradiography of the cultured cells revealed that a majority of mature PMNs were engaged in macromolecule synthesis, and an analysis of newly synthesized proteins by SDS-polyacrylamide gel electrophoresis showed that many different polypeptide chains were synthesized by these cells. The rate of [3H]uridine incorporation and the pattern of newly synthesized proteins were modulated by Con A and glucocorticoids. These results suggest that in spite of their short lifetime and a large performed enzymatic apparatus, mature PMNs retain a substantial capacity for RNA and protein synthesis; and, further, that modulation of macromolecule synthesis forms part of the mechanism by which PMNs respond to inflammatory and anti-flammatory stimuli.
Erratum for vol. 81, p. 935 (1993)

In the article by Shimada et al, entitled “Erythropoietin-Specific Cell Cycle Progression in Erythroid Subclones of the Interleukin-3-Dependent Cell Line 32D” which appeared in the February 15, 1993 issue (Vol 81, No 4, pp 935-941), an author name was incorrectly represented. The corrected listing of author names should read: Yoshihiro Shimada, Giovanni Migliaccio, Harold Ralph, and Anna Rita Migliaccio.
Design of a digital PID regulator based on look-up tables for control of high-frequency DC-DC converters (2003)

This paper describes design of a digital PID regulator based on look-up tables for high frequency DC-DC switching converters. The use of the took-up tables instead of multipliers enables a small. low-power implementation and operation at high switching frequencies. Design guidelines are given for the resolution and size of entries in the look-up tables. A design example and experimental results are presented for a digital controller IC used to control a 1 MHz, 2.7 V, 3 W buck converter.
MIRADAS for the Gran Telescopio Canarias (2016)

The Mid-resolution InfRAreD Astronomical Spectrograph (MIRADAS, a near-infrared multi-object echelle spectrograph operating at spectral resolution R=20,000 over the 1-2.5&mu;m bandpass) was selected by the Gran Telescopio Canarias (GTC) partnership as the next-generation near-infrared spectrograph for the world's largest optical/infrared telescope, and is being developed by an international consortium. The MIRADAS consortium includes the University of Florida, Universidad de Barcelona, Universidad Complutense de Madrid, Instituto de Astrofísica de Canarias, and Institut d'Estudis Espacials de Catalunya, as well as probe arm industrial partner A-V-S (Spain), with more than 45 Science Working Group members in 10 institutions primarily in Spain, Mexico, and the USA. In this paper, we review the overall system design and project status for MIRADAS during its early fabrication phase in 2016.
Fetal pyelectasis and Down syndrome: is genetic amniocentesis warranted? (1992)

An association between pyelectasis and Down syndrome has recently been reported. The purpose of this investigation was twofold: 1) to test the hypothesis that pyelectasis is more common in fetuses with Down syndrome, and 2) to determine whether genetic amniocentesis should be offered when dilated renal pelves are identified during fetal ultrasound examination. The study population of 5944 fetuses was separated into two groups by infant outcome: 1) phenotypically and/or chromosomally normal, and 2) chromosomally abnormal. Each group was examined for the presence of pyelectasis, defined as an anteroposterior renal pelvic diameter of 4 mm or greater before 33 weeks or 7 mm or greater after 33 weeks. Pyelectasis was observed in 17.4% (four of 23) of Down syndrome fetuses versus only 2% (120 of 5876) of normal controls, a statistically significant difference (P less than .001). The predictive value of pyelectasis for Down syndrome (one in 90) compares favorably with other accepted indications for genetic amniocentesis, such as advanced maternal age and low maternal serum alpha-fetoprotein (MSAFP). When fetuses with concomitant sonographic abnormalities were excluded, the predictive value of isolated pyelectasis fell to one in 340. We conclude that although renal pyelectasis is more common in Down syndrome fetuses, genetic amniocentesis should be reserved for those cases presenting other risk factors such as advanced maternal age, low MSAFP, or other sonographic abnormalities.