gebhart/patrepeval huggingface dataset:
Effects of Meloxicam and Phenylbutazone on Equine Gastric Mucosal Permeability (2012)

These results suggest that PBZ was associated with greater compromise to gastric mucosal integrity than meloxicam.
How biogenic terpenes govern the correlation between sulfuric acid concentrations and new particle formation (2008)

New particle formation has been observed to take place all around the world. However, because of the inability to determine the chemical composition of the smallest clusters or particles, indirect tools such as the correlation between nucleation rate and measured sulfuric acid concentrations have been used to infer the nucleation mechanism. In this study we describe the observed correlation with gaseous sulfuric acid concentrations by interactions of sesquiterpene oxidation products with sulfuric acid. Two formation pathways of nucleation initiating molecules are considered. The interaction of sulfuric acid with organic sulfates, which are formed from stabilized Criegee intermediates (sCIs, formed from sesquiterpenes), can be used to explain the observed squared relationship between particle formation rate and ambient sulfuric acid concentrations. The corresponding linear dependence is explained with the participation of secondary ozonides, which are formed from sCIs and aldehydes. Both pathways are negatively affected by increasing water vapor concentration as observed in recent studies. In order to check the assumptions made we apply the derived nucleation coefficients to measurements of the BACCI/QUEST IV campaign made during spring 2005 in Hyytiälä, Finland. A reasonable agreement between the measurement data and the predicted nucleation rates is found, giving support for the presented nucleation description.
Experimental implementation of adaptive control for flexible space structures (1988)

On-going research at The Aerospace Corporation studying the feasibility of applying adaptive control methodologies to the control of flexible space structures is described. A laboratory testbed was established to test system identification and control approaches. The laboratory set-up and controller design approach are discussed. The ARX least squares parameter estimation technique is analyzed in terms of frequency domain transfer function bias error. This analysis approach enables the determination of the effects of sampling rate, sensor type, and data prefiltering on the estimation performance. The ability to identify space structure dynamics over a range of frequencies is shown to be heavily dependent on these factors.
Echography of the Inferior Vena Cava is a Simple and Reliable Tool for Estimation of ‘Dry Weight’ in Haemodialysis Patients (1989)

Using echography, the diameter of the inferior vena cava (IVC) and its decrease on deep inspiration (collapse index) were evaluated in haemodialysis patients. The diameter of the IVC was expressed as an index to the body surface area (VCD) in mm/m2. Non-linear regression analysis in predicting mean right atrial pressure by VCD (mm/m2) and collapse index revealed a good correlation (r = 0.92; P less than 0.001) in both measurements. These results indicate that the IVC indices can be used as a parameter for both high and low filling pressures. Over-hydration (mean right atrial pressure greater than 7 mmHg) was defined as a collapse index of less than 40% and a VCD of more than 11.5 mm/m2, and underhydration (mean right atrial pressure less than 3 mmHg) as a VCD of less than 8 mm/m2 and collapse index of above 75%. In 22 patients in whom dry weight was determined on clinical grounds, only six had a correct dry weight according to IVC indices. Reliability of IVC indices for estimation of body fluid status was proved by the fact that during haemodialysis with fluid removal, postdialysis underhydrated patients according to IVC indices showed a decrease of mean arterial pressure and stroke volume, and an increase of heart rate. No such changes were observed in postdialysis normovolaemic and hypervolaemic patients, according to the vena cava indices. Furthermore, blood volume in normo- and hypervolaemic patients decreased much less than in hypovolaemic patients, despite the same amount of ultrafiltration. Total blood volume (ml/m2) and VCD (mm/m2) correlated significantly (r = 0.61; P less than 0.001), whereas there was no significant correlation between collapse index and blood volume.(ABSTRACT TRUNCATED AT 250 WORDS)
Therapeutic candidates for keloid scars identified by qualitative review of scratch assay research for wound healing (2021)

The scratch assay is an in vitro technique used to analyze cell migration, proliferation, and cell-to-cell interaction. In the assay, cells are grown to confluence and then 'scratched' with a sterile instrument. For the cells in the leading edge, the resulting polarity induces migration and proliferation in attempt to 'heal' the modeled wound. Keloid scars are known to have an accelerated wound closure phenotype in the scratch assay, representing an overactivation of wound healing. We performed a qualitative review of the recent literature searching for inhibitors of scratch assay activity that were already available in topical formulations under the hypothesis that such compounds may offer therapeutic potential in keloid treatment. Although several shortcomings in the scratch assay literature were identified, caffeine and allicin successfully inhibited the scratch assay closure and inflammatory abnormalities in the commercially available keloid fibroblast cell line. Caffeine and allicin also impacted ATP production in keloid cells, most notably with inhibition of non-mitochondrial oxygen consumption. The traditional Chinese medicine, shikonin, was also successful in inhibiting scratch closure but displayed less dramatic impacts on metabolism. Together, our results partially summarize the strengths and limitations of current scratch assay literature and suggest clinical assessment of the therapeutic potential for these identified compounds against keloid scars may be warranted.
In VivoEffects of CpG Oligodeoxynucleotide on Eimeria Infection in Chickens (2004)

Poultry coccidiosis is the major parasitic disease of poultry and, until now, no recombinant vaccine has been developed. Short oligodeoxynucleotides (ODNs) containing unmethylated CpG motifs (CpG ODNs) have been shown to be effective immunoprotective agents and vaccine adjuvants in mammalian systems. Their use in poultry to protect against intracellular parasites has not been reported to date. The present work investigated the effects of CpG ODN treatment on host susceptibility to Eimeria infection in two chicken strains with different genetic background, SC and TK. The data show that CpG ODN enhanced the birds' resistance to coccidiosis in a normally susceptible chicken strain (TK), as shown by reduced oocyst shedding and improved weight gain. CpG treatment had a differential effect on body weight gains and serum antibody responses, depending on the chicken strain and ODN dose, delivery route, and backbone. This study shows for the first time that CpG ODNs could be used as immunoprotective agents in Eimeria-infected chickens to enhance resistance to the pathogen and improve performance. Future research is needed to optimize their use alone and as vaccine adjuvants that may lead to better and more efficient vaccine applications.
Photoreceivers for 100 Gbit/s Applications (2007)

Waveguide integrated photodetectors with 100 GHz bandwidth were developed. Different transmission experiments have demonstrated their capability for 107 Gbit/s applications. Design and results for separately packaged photodiodes and co-packaged receivers with 1 x 2 demultiplexer are shown.
Plasma lipids and apolipoproteins A and B in human pregnancy. (1984)

A cross sectional study was carried out in 200 normal pregnant women between 8-40th weeks of gestation, 25 women during delivery and 25 women 6 weeks after delivery. Plasma and lipoprotein lipids were measured using standard procedures. Apolipoprotein A (Apo A) and Apolipoprotein B (Apo B), were measured by electroimmunoassay. Plasma levels of Apo A were elevated in pregnant women but the elevations were not significant until 17-20 weeks of gestation. Apo A during pregnancy was significantly correlated (p less than 0.001) with high density lipoprotein cholesterol (HDL-C). The level of Apo B increased progressively during pregnancy and it was significantly correlated (p less than 0.001) with total cholesterol (TC), plasma triglycerides (TG) and phospholipids (PL). Apo A and Apo B levels returned to non pregnant values within the puerperium, whereas TC, TG and PL remained significantly elevated above controls (p less than 0.01) 6 weeks post partum.
Experiment and the foundations of quantum physics (1999)

Instead of having to rely on gedanken (thought) experiments, it is possible to base this discussion of the foundations of quantum physics on actually performed experiments because of the enormous experimental progress in recent years. For reasons of space, the author discusses mainly experiments related to the Einstein-Podolsky-Rosen paradox and Bell's theorem, that is, to quantum entanglement. Not only have such fundamental experiments realized many historic proposals, they also helped to sharpen our quantum intuition. This recently led to the development of a new field, quantum information, where quantum teleportation and quantum computation are some of the most fascinating topics. Finally the author ventures into a discussion of future prospects in experiment and theory.
Etching Characteristics and Profile Control in a Time Multiplexed Inductively Coupled Plasma Etcher (1998)

This paper reports on a complete designed experiment of a deep reactive ion etch process in which matrices of 8 and 4 variables were explored in order to optimize uniformity, anisotropy, Aspect Ratio Dependent Etching (ARDE), photoresist and silicon etching rate.A database results from these experiments which permits customiz.ation of operating conditions to obtain desired etch characteristics.
Modulated 3D Cross-Correlation Dynamic Light Scattering Applications for Optical Biosensing and Time-Dependent Monitoring of Nanoparticle-Biofluid Interactions (2020)

This paper reviews dynamic light scattering (DLS) of gold nanoparticle-protein interactions for the model protein bovine serum albumin (BSA), as well as in complex biofluids, at the example of mouse serum. DLS data of nanorods of various aspect ratio, of proteins and of mouse serum are discussed in terms of the analysis of their hydrodynamic radii, leading to the distinction of rotational and translational motion as well as to the detection of agglomerates. We address in particular advances obtained by modulated 3D cross correlation dynamic light scattering and recent progress using the CORENN algorithm for analysis of DLS data.
Truncated Maximal Ratio Combining for Iterative Multiuser Decoding (2006)

In this paper, the concept of information combining is investigated for iterative multiuser decoding. This is done by applying recursive maximal ratio combining (MRC) over iterations to interference cancellation based multiuser detectors. Here, we show that combining over all iterations may not be appropriate as correlations build up. Numerical results show that applying MRC only over the first few iterations can improve the bit error rate performance with only a modest increase in complexity, as compared to no combining
Charge Transport across Proteins inside Proteins: Tunneling across Encapsulin Protein Cages and the Effect of Cargo Proteins (2023)

Charge transport across proteins can be surprisingly efficient over long distances-so-called long-range tunneling-but it is still unclear as to why and under which conditions (e.g., presence of co-factors, type of cargo) the long-range tunneling regime can be accessed. This paper describes molecular tunneling junctions based on an encapsulin (Enc), which is a large protein cage with a diameter of 24 nm that can be loaded with various types of (small) proteins, also referred to as "cargo". We demonstrate with dynamic light scattering, transmission electron microscopy, and atomic force microscopy that Enc, with and without cargo, can be made stable in solution and immobilized on metal electrodes without aggregation. We investigated the electronic properties of Enc in EGaIn-based tunnel junctions (EGaIn = eutectic alloy of Ga and In that is widely used to contact (bio)molecular monolayers) by measuring the current density for a large range of applied bias of ±2.5 V. The encapsulated cargo has an important effect on the electrical properties of the junctions. The measured current densities are higher for junctions with Enc loaded with redox-active cargo (ferritin-like protein) than those junctions without cargo or redox-inactive cargo (green fluorescent protein). These findings open the door to charge transport studies across complex biomolecular hierarchical structures.
Classification algorithms applied to narrative reports. (1999)

Narrative text reports represent a significant source of clinical data. However, the information stored in these reports is inaccessible to many automated decision support systems. Data mining techniques can assist in extracting information from narrative data. Multiple classification methods, such as rule generation, decision trees, Bayesian classifiers, and information retrieval were used to classify a set of 200 chest X-ray reports according to 6 clinical conditions indicated. A general-purpose natural language processor was used to convert the narrative text into a coded form that could be used by the classification algorithms. Significant differences in performance were found between algorithms. The best performing algorithm applied to the processor output was significantly better than information retrieval applied to raw text. Predictor variables from the coded processor output were limited to avoid overfitting. Methods that limited by domain knowledge performed significantly better than those that limited by conditional probabilities of the variables in the training set. Algorithms were also shown to be dependent on training set size.
Multichannel processing for dispersion curves extraction of ultrasonic axial-transmission signals: Comparisons and case studies (2016)

Some pioneering studies have shown the clinical feasibility of long bones evaluation using ultrasonic guided waves. Such a strategy is typically designed to determine the dispersion information of the guided modes to infer the elastic and structural characteristics of cortical bone. However, there are still some challenges to extract multimode dispersion curves due to many practical limitations, e.g., high spectral density of modes, limited spectral resolution and poor signal-to-noise ratio. Recently, two representative signal processing methods have been proposed to improve the dispersion curves extraction. The first method is based on singular value decomposition (SVD) with advantages of multi-emitter and multi-receiver configuration for enhanced mode extraction; the second one uses linear Radon transform (LRT) with high-resolution imaging of the dispersion curves. To clarify the pros and cons, a face to face comparison was performed between the two methods. The results suggest that the LRT method is suitable to separate the guided modes at low frequency-thickness-product ( fh) range; for multimode signals in broadband fh range, the SVD-based method shows more robust performances for weak mode enhancement and noise filtering. Different methods are valuable to cover the entire fh range for processing ultrasonic axial transmission signals measured in long cortical bones.
A combined arc-melting and tilt-casting furnace for the manufacture of high-purity bulk metallic glass materials (2011)

An arc-melting furnace which includes a tilt-casting facility was designed and built, for the purpose of producing bulk metallic glass specimens. Tilt-casting was chosen because reportedly, in combination with high-purity processing, it produces the best fatigue endurance in Zr-based bulk metallic glasses. Incorporating the alloying and casting facilities in a single piece of equipment reduces the amount of laboratory space and capital investment needed. Eliminating the sample transfer step from the production process also saves time and reduces sample contamination. This is important because the glass forming ability in many alloy systems, such as Zr-based glass-forming alloys, deteriorates rapidly with increasing oxygen content of the specimen. The challenge was to create a versatile instrument, in which high purity conditions can be maintained throughout the process, even when melting alloys with high affinity for oxygen. Therefore, the design provides a high-vacuum chamber to be filled with a low-oxygen inert atmosphere, and takes special care to keep the system hermetically sealed throughout the process. In particular, movements of the arc-melting electrode and sample manipulator arm are accommodated by deformable metal bellows, rather than sliding O-ring seals, and the whole furnace is tilted for tilt-casting. This performance of the furnace is demonstrated by alloying and casting Zr(55)Cu(30)Al(10)Ni(5) directly into rods up to ø 10 mm which are verified to be amorphous by x-ray diffraction and differential scanning calorimetry, and to exhibit locally ductile fracture at liquid nitrogen temperature.
Accelerated Discovery and Design of Nano-Material Applications in Nuclear Power by Using High Performance Scientific Computing (2015)

The accelerated development of nano-sciences and nano-material systems and technologies is made possible through the use of High Performance Scientific Computing (HPSC). HPSC exploration ranges from nano-clusters to nano-material behavior at mezzo-scale and specific macro-scale products. These novel nano-materials and nano-technologies developed using HPSC can be applied to improve nuclear devices' safety and performance. This chapter explores the use of HPSC.
Decoherence of a Quantum Bit Circuit (2006)

Solid state quantum bit circuits (qubits) are candidates for the implementation of quantum processors, which can in principle perform some computational tasks beyond reach of classical sequential processors. Decoherence is there a key issue since electrical circuits are more prone to decoherence than microscopic objects such as atoms. We introduce the different families of solid state qubits, which are either based on single particle states in semiconductor nanostructures, or on global quantum states of superconducting Josephson circuits. We treat more in detail the Cooper pair box Josephson circuit, and the quantronium circuit derived from it. In this device, a decoupling strategy of the circuit from the outside circuitry allows to improve quantum coherence. We expose results obtained on the manipulation of the qubit state in the quantronium. We develop a general framework for understanding decoherence in qubit circuits, and show how coherence time measurements allow to characterize noise sources coup.
Effect of pH and time on the quantity of readily available water within fresh cheese curd (1997)

Some of the textural changes that occur early in cheese maturation may be related to the redistribution of water within the cheese matrix. To examine this, a model cheese curd system was devised and explored. Initially, cheese curd was prepared using starter and chymosin and the curd pH was controlled by varying the draining and salting pH values. The quantity of serum that could be centrifuged from the resultant curd was less for lower pH curd and decreased in volume with time. The curd pH decreased with time. In the protocol finally adopted, milk was acidified with lactic acid and coagulated with Rennilase 46L. After cheddaring, salting and light pressing, the samples of this curd were finely diced and mixed with glucono-δ-lactone to give curd samples with comparable moisture contents, similar casein proteolysis rates but different pH values. The quantity of serum that could be centrifuged from these samples was greater for pH 5·6 curd than for pH 5·2 curd and decreased faster for the lower pH curd. Neither the curd moisture nor the pH changed significantly during curd storage and the casein proteolysis was low. These results for the model curd system are consistent with known water absorption characteristics of casein curd under ‘equilibrium’ conditions and the effects of pH and mineral salts on this absorption. It was concluded that, during the early stages of cheese ripening, there may be a redistribution of moisture within the cheese, related to the basic properties of the protein matrix and the transient effects of curd salting, rather than as a direct consequence of glycolytic and proteolytic changes.
Data analysis for continuous EEG monitoring in the ICU: seeing the forest and the trees. (2005)

Continuous EEG monitoring (CEEG) is a powerful tool for evaluating cerebral function in obtunded and comatose critically ill patients. The ongoing analysis of CEEG data is a major task because of the volume of data generated during monitoring and the need for near real-time interpretation of a patient's EEG patterns. Advances in digital EEG data acquisition, computer processing, data transmission, and data display have made CEEG monitoring in the intensive care unit technically feasible. A variety of quantitative EEG tools such as Fourier analysis and amplitude-integrated EEG, and other methods of data analysis such as computerized seizure detection, increasingly allow for focused review of EEG epochs of potential interest. These tools reduce the tremendous time burdens that accompany analysis of the complete CEEG data stream, and allow bedside personnel and nonexpert staff to potentially recognize significant EEG changes in a timely fashion. This article uses literature review and clinical case examples to illustrate techniques for the display and analysis of intensive care unit CEEG recordings. Areas requiring further research and development are discussed.
Effect of Calcinating Temperature and Mn doping on Dielectric Properties of temperature‐stable BaTiO 3 ‐Based X8R Ceramics (2012)

Systematic investigation has been made on the structure and dielectric properties of Mn CO 3 ‐doped barium titanate‐based X8R ceramics, to reveal the relationship between the manufacturing process and dielectric properties. The dielectric ceramic sintered at 950°C showed high permittivity and low dielectric loss, meeting X8R specifications. Transmission electron microscopy and EDS analysis were used. The results suggested that the temperature‐stable BaTiO 3 ‐based X8R ceramics with the good dielectric properties can be prepared through the BaTiO 3 calcined at 1150°C and doped with 0.7 wt% Mn CO 3.
Development of New Xtronic CVT for Middle Class Vehicle (2005)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.