gebhart/patrepeval huggingface dataset:
Advanced mimo-cdma receiver for interference suppression: algorithms, system-on-chip architectures and design methodology (2005)

MIMO (Multiple Input Multiple Output) technology is proposed in CDMA systems for much higher rate packet services. The receiver architecture is essential for the mobile devices to support high speed multimedia service. The design challenges come from both detection algorithms and hardware architectures. Much more complicated algorithms are required to suppress various interferences. However, the current hardware design architecture and methodology is falling far behind the requirements of small size, low cost and power consumption.\nSystem-On-Chip (SoC) architectures are a major revolution taking place in the design of integrated circuits due to many advantages in the power consumption and compact size. The VLSI-oriented complexity reduction of the numerical algorithms plays an essential role to design efficient real-time architectures. Thus, the thesis contributes to three major aspects: to propose high performance algorithms with realistic complexity in different channel conditions; to propose real-time SoC architectures with area/speed/power efficiency; and to propose an efficient design methodology for modelling, partitioning/binding, verification and synthesis of the wireless systems.\nSpecifically, to cut the design cycle and enable extensive architecture tradeoff study, an integrated wireless development methodology by High-Level-Synthesis for joint algorithm and architecture optimization is proposed. To address the performance/complexity tradeoff, we propose two LMMSE equalizer algorithms and SoC architectures for different channel conditions. Both an FFT circulant MIMO equalizer and a frequency domain iterative equalizer are proposed to avoid Direct-Matrix-Inverse for the well-conditioned channel as well as long channels working in bad conditions respectively. We then propose a displacement Kalman equalizer with VLSI-oriented architectural optimization for better performance in fast fading environments. For systems with the multi-users' signaling, we propose an adaptive Parallel-Residue-Compensation architecture with stage and user specific weights by viewing the multiple transmitter antennas as virtual users to cancel the interferences explicitly. The increased accuracy in interference cancellation leads to significant performance gain over both the complete and partial PIC. The complexity is reduced by using the commonality to avoid the direct interference cancellation. Finally, dynamic power management schemes are proposed to reduce the power consumption in the VLSI architectures using the inherent features of the interference suppression algorithms.
ChemInform Abstract: Total Syntheses of Arenamides A, B and C. (2014)

Abstract The first synthesis of these NFϰB inhibitors is presented.
Record of insect pollinators of Moringa oleifera lam. (2018)

Present study was carried out to record the insect pollinators on the blossom of Moringa oleifera during its flowering season. All the insects that visited the M. oleifera flowers between 6.00am and 6:00pm were observed and collected. The diversity and abundance of the insect visitors on the blossom were determined. Six species of Apidae family, two species of Vespidae, two species of Papilionidae family and one species of Nymphalidae family were found visiting the flowers of M. oleifera. A. florea was recorded as top workers on inflorescence of M. oleifera as pollen and nectar gatherers followed by Apis dorsata, Amegilla sp., Megachile sp. and Xylocopa sp.
Models for a New Profit-Based Methodology for Statistical Design of Integrated Circuits (1986)

A new methodology for the optimization of integrated circuit (IC) parameters which takes into consideration realistic statistical fluctuations occurring in their fabrication, is proposed. The methodology is based on a problem formulation which consists of maximizing a criterion of goodness never before used in statistical circuit design. The criterion is one that recognizes the ultimate economic goal of engineering design--profit expected from the production and sale of the product being designed. In particular, this criterion is motivated in the general context of engineering design and of statistical circuit optimization. The form of profit most appropriate to statistical circuit optimization is specified. The design parameters of the methodology are identified, and the dependence of profit on them modeled.
Studies on the Conditions, Scope and Mechanism of the von Richter Reaction1 (1954)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStudies on the Conditions, Scope and Mechanism of the von Richter Reaction1J. F. Bunnett, Michael M. Rauhut, David Knutson, and George E. BussellCite this: J. Am. Chem. Soc. 1954, 76, 22, 5755–5761Publication Date (Print):November 1, 1954Publication History Published online1 May 2002Published inissue 1 November 1954https://pubs.acs.org/doi/10.1021/ja01651a039https://doi.org/10.1021/ja01651a039research-articleACS PublicationsRequest reuse permissionsArticle Views584Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Selective ROCK2 inhibitor reverses experimental chronic graft-versus-host disease via concurrent regulation of STAT3/STAT5 phosphorylation (TRAN1P.933) (2015)

Abstract Rho-associated kinase 2 (ROCK2) was recently shown to be implicated in regulation of IL-21 and IL-17 secretion in mice and humans. Here, we report that the potent and highly selective ROCK2 inhibitor KD025 effectively reverses an established chronic graft-versus-host (cGVHD) murine model driven by IL-21 and characterized by an aggressive multiorgan system fibrotic disease. KD025 treatment leads to a dose dependent decrease in the development of pathogenic pulmonary function which correlates with a marked reduction of antibody and collagen deposition in the lungs of treated mice to levels comparable to non-cGVHD controls. The spleens of mice treated with KD025 had a decrease in the frequency of germinal centers associated with a reduction in STAT3 and concurrent increase in STAT5 phosphorylation, supporting the molecular mechanism of targeted ROCK2 inhibition in humans. The critical role of STAT3 activation in this cGVHD model was further confirmed by data showing that mice transplanted with inducible STAT3 deficient T cells or BM cells had pulmonary function comparable to the healthy negative controls. Finally, KD025 effectively blocked the progression of sclerodermatous cGVHD model characterized by improvements in weight loss, posture and skin integrity of treated animals. Together, these data demonstrate the importance of ROCK2 signaling in STAT3-dependent regulation of cytokine secretion and highlight the potential of targeted ROCK2 inhibition for cGVHD therapy.
Inflammation, Atherosclerosis, and Ischemic Events — Exploring the Hidden Side of the Moon (1997)

Cardiac and cerebral ischemic events develop unpredictably in patients with widely varying degrees of atherosclerotic disease. Thus, a major area of research is the study of the stimuli that provoke ischemic events. The weak relation between ischemic events and flow-limiting stenoses in the coronary and carotid arteries leaves room for innovative research.1 However, it is easier to study the details of accepted paradigms than it is to develop new hypotheses, just as it was easier to map the visible face of the moon than it was to explore its hidden side.The study by Ridker et al. in this issue . . .
ChemInform Abstract: Preparation of trans‐3‐(Hydroxymethyl)‐2‐vinyloxetane (II) via Allyloxycarbanion‐Mediated Carbon‐Carbon Bond Formation in Allyl Glycidyl Ether (I). (1988)

Abstract (ICHIKA‐ WA , Y.; NIITSUMA, S.; KATO, K.; TAKITA, T.; J. Chem.
Production d'anticorps spécifiques in vitro par culture de lymphocytes B humains (2008)

Les anticorps, piliers de la réponse immunitaire humorale, sont fréquemment utilisés pour traiter certaines immunodéficiences et maladies autoimmunes. Des préparations d'anticorps spécifiques à un antigène sont également administrées à des individus, suite à un contact avec un pathogène. Cependant, nous sommes limités dans leur production ainsi que dans la variété des spécificités antigéniques puisque leur préparation dépend de la disponibilité d'individus hyperimmunisés. Ce projet a donc pour objectif de produire des anticorps spécifiques in vitro en cultivant les lymphocytes B humains isolés du sang de participants. En stimulant les lymphocytes B humains avec du LPS d'Escherichia coli, la sécrétion d'anticorps spécifiques et la sécrétion de cytokines ont augmenté. Nous pensons que ce mécanisme accélère la réponse secondaire lors d'une infection bactérienne. Nous avons également tenté de stimuler la prolifération des lymphocytes B humains en surexprimant le gène AgT, un gène stimulant la croissance cellulaire chez les cellules COS7. Cependant, nous n'avons pas été en mesure d'obtenir obtenir un effet biologique.
Improvement on LEACH Protocol of Wireless Sensor Network (2007)

This paper studies LEACH protocol, and puts forward energy-LEACH and multihop-LEACH protocols. Energy-LEACH protocol improves the choice method of the cluster head, makes some nodes which have more residual energy as cluster heads in next round. Multihop-LEACH protocol improves communication mode from single hop to multi-hop between cluster head and sink. Simulation results show that energy-LEACH and multihop-LEACH protocols have better performance than LEACH protocols.
Benefit of B7-1 staining and abatacept for treatment-resistant post-transplant focal segmental glomerulosclerosis in a predominantly pediatric cohort: time for a reappraisal (2022)

Podocyte B7-1 staining in biopsies of KTRs with post-transplant FSGS identifies a subset of patients who may benefit from abatacept. A higher resolution version of the Graphical abstract is available as Supplementary information.
Indagine conoscitiva sulla determinazione degli autoanticorpi nella malattia diabetica nei Laboratori italiani (2014)

Il processo autoimmune anti-insula pancreatica che caratterizza il diabete mellito di tipo 1 e il diabete autoimmune latente dell’adulto è accompagnato dalla comparsa di autoanticorpi circolanti anti-decarbossilasi dell’acido glutammico (GADA), anti-insulina (IAA), anti-proteina-tirosin-fosfatasi IA-2 (IA-2A) e anti-trasportatore dello zinco ZnT8 (ZnT8A). La diffusione di metodiche per la determinazione di autoanticorpi anti-insula pancreatica in Laboratori pubblici italiani non è al momento nota. Un questionario per la raccolta di informazioni relative all’esecuzione di determinazione di autoanticorpi anti-insula pancreatica (ICA) è stato diffuso a Laboratori di strutture pubbliche del territorio nazionale. Sono stati raccolti 61 questionari; 41 Laboratori hanno dichiarato di effettuare analisi di autoanticorpi anti-insula pancreatica o di raccogliere campioni da spedire a Laboratori esterni per tali analisi. GADA sono stati analizzati in 30 Laboratori, ICA in 26 Laboratori, IA-2A in 17 Laboratori e IAA in 16 Laboratori. Un solo Laboratorio ha dichiarato di effettuare l’analisi ZnT8A per uso clinico. Metodiche radioimmunologiche sono state utilizzate dal 61% dei Laboratori che hanno determinato GADA, dal 75% dei Laboratori che hanno determinato IA-2A e dal 65% dei Laboratori che hanno determinato IAA. I rimanenti Laboratori hanno utilizzato metodiche ELISA. Gli ICA sono stati determinati con metodica di immunofluorescenza indiretta nel 96% dei Laboratori, ma sezioni criostatiche di pancreas umano sono state utilizzate solo dal 17% dei Laboratori. La determinazione di ICA è diffusa anche a Laboratori ospedalieri italiani esclusivamente o prevalentemente clinici. L’analisi anticorpale più diffusa è quella dei GADA. Un elevato numero di Laboratori effettua ancora l’analisi ICA con immunofluorescenza indiretta, in 6 casi come unica determinazione anticorpale. Metodiche radioimmunologiche ad alta sensibilità e specificità sono utilizzate in circa il 60–75% dei Laboratori.
Data Supplement from Acquired Resistance to Endocrine Treatments Is Associated with Tumor-Specific Molecular Changes in Patient-Derived Luminal Breast Cancer Xenografts (2023)

&lt;p&gt;Supplementary Table S4. Genes differentially expressed between HBCx22 OvaR and HBCx22 and associated gene ontology terms.&lt;/p&gt;
Segmentation and linguistic summarization of voxel environments using stereo vision and genetic algorithms (2010)

For reasons such as computational complexity, spatial and temporal information reduction, and human understandability, it is important that computer vision systems be equipped with the means to summarize their content in a natural language. Such rich descriptions are of use by both humans and computers for describing, recognizing, and tracking objects, activity, and their interactions at a desired level of abstraction. A genetic algorithm is introduced here for segmenting non-human objects deemed relevant to human activity analysis in stereo vision acquired voxel environments. This approach is of use in an Eldercare setting as it relates to monitoring the “well-being” of residents through acquiring and detecting deviations in patterns of typical behavior as well as recognizing abnormal events, such as fall detection.
Urea Transporter Physiology Studied in Knockout Mice (2012)

In mammals, there are two types of urea transporters (UTs), UT-A and UT-B. The UT-A transporter is mainly expressed in kidney epithelial cells; while UT-B demonstrates a broader distribution in kidney, heart, brain, testis, urinary tract and other tissues. Over the past few years, multiple UT knockout mouse models have been generated enabling us to explore the physiological roles of the different UTs. In the kidney, deletion of UTA1/A3 results in polyuria and a severe urine concentrating defect, indicating that intrarenal recycling of urea plays a crucial role in the overall capacity to concentrate urine. Since UT-B has a wide distribution, multiple phenotypic abnormalities were found in UT-B null mice, such as defective urine concentration, heart block with aging, depression-like behavior and earlier male sexual maturation. This review summarizes the new insights of urea transporter functions in different organs from UT knockout mice. Finally, we take a glance at the pharmacological prospect of UTs.
Validation and Support of a Quantitative Infrared Instrument Facility and Generation of a Library of Chemical Warfare and Related Materials by Fourier Transform Infrared Spectroscopy (2006)

Approved for public release: distribution is unlimited. 20070907323 ABERDEEN PROVING GROUND, MD 21010-5424 DISCLAIMER The findings in this report are not to be construed as an official Department of the Army position unless so designated by other authorizing documents. REPORT DOCUMENTATION PAGE Form Approved OMB No. 0704-0188 Public reporting burden for this collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing this collection of information. Send comments regarding this burden estimate or any other aspect of this collection of information, including suggestions for
Ultra-Shallow and Abrupt Boron Profiles in Si by δ-Doping Technique (1995)

Ultra-shallow and abrupt boron (B) profiles in Si are achieved by molecular beam epitaxy, and the thermal stability of these profiles is closely examined. Oxidation-enhanced diffusion of a B-δ-doped Si layer is observed at 700-850° C. However, broadening of the δ-doped layer during gate oxidation can be minimized by wet O 2 oxidation owing to the shorter oxidation time than that of dry O 2 . The sheet resistance of heavily δ-doped layers with ultra-shallow junctions is 1 kΩ /sq which is almost constant even after thermal annealing. This value is about 1/10 of the reported value obtained by solid-phase diffusion from boron-silicated glass film, in which solid solubility limits the maximum carrier concentration.
Introduction: Double Desire (2014)

This book is the outcome of a session that addressed issues of Indigenous contemporaty art at the 2013 College Art Association (CAA) conference in New York. If Indigenous art was once considered a highly localised pre-national expression its contemporary fommations have a very global and post-national perspective. This globalism is evident in the geographic range of essays in this book, which cover art in Africa, Australia, Canada Mexico and the United States, with scholars drawn from a similar range of countries with the notable absence of Europe.
The Ontogeny of a Neutrophil: Mechanisms of Granulopoiesis and Homeostasis (2018)

Comprising the majority of leukocytes in humans, neutrophils are the first immune cells to respond to inflammatory or infectious etiologies and are crucial participants in the proper functioning of both innate and adaptive immune responses. From their initial appearance in the liver, thymus, and spleen at around the eighth week of human gestation to their generation in large numbers in the bone marrow at the end of term gestation, the differentiation of the pluripotent hematopoietic stem cell into a mature, segmented neutrophil is a highly controlled process where the transcriptional regulators C/EBP-α and C/EBP-ε play a vital role. Recent advances in neutrophil biology have clarified the life cycle of these cells and revealed striking differences between neonatal and adult neutrophils based on fetal maturation and environmental factors. Here we detail neutrophil ontogeny, granulopoiesis, and neutrophil homeostasis and highlight important differences between neonatal and adult neutrophil populations.
Mechanisms of Action of TGF‐β in Cancer (2007)

Transforming growth factor-beta (TGF-beta) induces cell differentiation and suppresses cell proliferation, but the mechanisms underlying the actions of TGF-beta remain to be fully elucidated. Recent studies suggest that TGF-beta suppresses neoplastic cell development by employing Smad3 protein to repress the gene of human telomerase reverse transcriptase (hTERT). In human breast cancer cells, TGF-beta induces rapid phosphorylation and subsequent entry of Smad3 into the nucleus. In the nucleus, Smad3 binds to the hTERT gene promoter directly and inhibits hTERT gene transcription activity. By interacting with c-myc, Smad3 also represses the c-myc gene. Thus, TGF-beta prevents continuous cell proliferation by switching off telomerase activity through Smad3 repression of the hTERT gene and the action of c-myc. Modulating the interface between Smad3 and the hTERT gene, and the potential feedback loop from telomeres to Smad3 via Smurf2, may represent a novel approach to regulate cell lifespan of proliferation.
Crystal structure and luminescence properties of LiYP4O12:Ce3 +phosphor (2010)

LiYP(4)O(12) polyphosphate doped with Ce(3+) ions was prepared by the melt solution technique. The crystal structure, interatomic distances, and atom coordination numbers were determined using x-ray powder diffraction. A study of the spectral-kinetic luminescent properties was performed employing excitation with pulsed radiation from a synchrotron (UV-VUV range) and a laboratory x-ray source. The characteristics of Ce(3+) luminescence, namely the emission doublet maxima at 3.97 and 3.72 eV and the 4f-5d excitation maxima at 4.20, 5.11, 5.40, 5.65 and 6.55 eV, are discussed in terms of crystal field splitting in a low-symmetry site of the LiYP(4)O(12) host lattice. The location of the Ce(3+) energy levels with respect to the valence and conduction bands of the LiYP(4)O(12) host is estimated from the temperature dependence of the decay time measured for Ce(3+) 5d-4f luminescence.
Coordination of XeF2to Calcium and Cadmium Hexafluorophosphates(V) (2005)

[M(XeF2)5](PF6)2 (M = Ca, Cd) complexes were prepared by the reaction of MF2 and XeF2 under pressure of gaseous PF5 in anhydrous HF as solvent. The coordination sphere of the Ca atom consists of nine fluorine atoms: three from two PF6(-) units (one bidentate and one monodentate) and one from each of six XeF2 molecules. The coordination sphere of the Cd atom consists of eight fluorine atoms: one from each of two PF6(-) units and one from each of six XeF2 molecules. Two of the XeF2 ligands about M in each compound are bridging ligands and are each linked to two M, generating infinite (-M-F-Xe-F-M-F-Xe-F-) chains along the b-axis in the Ca salt and along the c-axis in the Cd compound. The Cd2+ cation is smaller and more electronegative than the Ca2+ cation. These differences account for the higher F ligand coordination in the Ca2+ salt and for other structural features that distinguish them. The different stoichiometry of the PF6(-) salts when compared with their AsF6(-) analogues, which have the composition [M(XeF2)4](AsF6)2 (M = Ca, Cd), is in accord with the lower F ligand charge in the AsF6(-) when compared with that in the PF6(-) compound. Indeed, the AsF6(-) ligand charges appear to be similar to those in the XeF2-bridged species.
ChemInform Abstract: A Simple and Efficient Thiocyanation of Indoles, Anilines and Keto Compounds Catalyzed by a Polystyrene Resin Amberlyst‐15. (2010)

Abstract Advantages of the title procedure are the mild reaction conditions, the ease of product isolation, and the cheap and commercially available catalyst.
Piezoelectric properties of polyamide 11/NaNbO3 nanowire composites (2012)

Abstract Polyamide 11(PA 11)/sodium niobate nanowire (NW) 0–3 composites with different volume fractions of NWs were synthesized. The electric polarization ( P ) was measured as a function of the applied electric field ( E ). The P – E hysteresis loop was used to work out the remanent polarization P r of these materials. The dielectric permittivity and the piezoelectric strain constant were determined. Good impedance matching between inorganic and organic phases leads to higher electroactivity than conventional lead-free 0–3 composites. The piezoelectric voltage of the PA 11/NaNbO 3 NW composites is of the same order as those obtained for fluorinated piezoelectric polymers. These composites could have some applications in flexible, low-cost, environmentally friendly piezoelectric sensors and actuators.
Mouse strain differences in response to oral immunotherapy for peanut allergy (2019)

Taken together, these results show that the C3H strain is more suitable to study clinical outcomes of OIT, whereas the BALB/c strain is more optimal to study T cell responses.