gebhart/patrepeval huggingface dataset:
An object oriented approach for structuring ISDN call processing software (1992)

In 1989 a pilot project was started at Siemens to gain experience concerning the applicability of object oriented techniques (OOT) in the field of switching system software. In this pilot project an ISDN prototype switch was implemented applying both the principles of object oriented design and the programming language Object-CHILL, an object oriented extension of CHILL. The authors deal with the results reached so far within this project. In this context three subjects are considered in more detail: the influence of OOT on the software development process, the resulting structure of the ISDN call processing software and the impact of OOT on the tool set. In general many of the advantages claimed to be associated with object orientation in other application fields could be confirmed for switching system software. >
Training Support Vector Machines using Coresets (2017)

We present a novel coreset construction algorithm for solving classification tasks using Support Vector Machines (SVMs) in a computationally efficient manner. A coreset is a weighted subset of the original data points that provably approximates the original set. We show that coresets of size polylogarithmic in $n$ and polynomial in $d$ exist for a set of $n$ input points with $d$ features and present an $(ε,δ)$-FPRAS for constructing coresets for scalable SVM training. Our method leverages the insight that data points are often redundant and uses an importance sampling scheme based on the sensitivity of each data point to construct coresets efficiently. We evaluate the performance of our algorithm in accelerating SVM training against real-world data sets and compare our algorithm to state-of-the-art coreset approaches. Our empirical results show that our approach outperforms a state-of-the-art coreset approach and uniform sampling in enabling computational speedups while achieving low approximation error.
Orientational Disorder in Epitaxially Connected Quantum Dot Solids (2019)

Periodic arrays of strongly coupled colloidal quantum dots (QDs) may enable unprecedented control of electronic band structure through manipulation of QD size, shape, composition, spacing, and assembly geometry. This includes the possibilities of precisely engineered bandgaps and charge carrier mobilities, as well as remarkable behaviors such as metal-insulator transitions, massless carriers, and topological states. However, experimental realization of these theoretically predicted electronic structures is presently limited by structural disorder. Here, we use aberration-corrected scanning transmission electron microscopy to precisely quantify the orientational disorder of epitaxially connected QD films. In spite of coherent atomic connectivity between nearest neighbor QDs, we find misalignment persists with a standard deviation of 1.9°, resulting in significant bending strain localized to the adjoining necks. We observe and quantify a range of out-of-plane particle orientations over thousands of QDs and correlate the in-plane and out-of-plane misalignments, finding QDs misoriented out-of-plane display a statistically greater misalignment with respect to their in-plane neighbors as well. Using the bond orientational order metric ψ<sub>4</sub>, we characterize the 4-fold symmetry and introduce a quantification of the local superlattice (SL) orientation. This enables direct comparison between local orientational order in the SL and atomic lattice (AL). We find significantly larger variations in the SL orientation and a statistically robust but locally highly variable correlation between the orientations of the two differently scaled lattices. Distinct AL and SL behaviors are observed about a grain boundary, with a sharp boundary in the AL orientations, but a more smooth transition in the SL, facilitated by lattice deformation between the neighboring grains. Coupling between the AL and SL is a fundamental driver of film growth, and these results suggest nontrivial underlying mechanics, implying that simplified models of epitaxial attachment may be insufficient to understand QD growth and disorder when oriented attachment and superlattice growth occur in concert.
Ethanol‐Altered Liver‐Associated T Cells Mediate Liver Injury in Rats Administered Concanavalin A (Con A) or Lipopolysaccharide (LPS) (1999)

Chronic ethanol consumption induces a lesion in a pool of liver-associated T cells which can mediate liver injury after polyclonal mitogen activation.
Stimuli‐responsive poly(hydroxyethyl methacrylate) hydrogels from carboxylic acid‐functionalized crosslinkers (2019)

Tailoring hydrogel properties by modifications of the crosslinker structure is a good method for the design of hydrogels with a wide range of properties. In this study, two novel carboxylic acid-functionalized dimethacrylate crosslinkers (1a and 2a) are synthesized by the reaction of poly(ethylene glycol) or 2-hydroxyethyl disulfide with tert-butyl α-bromomethacrylate followed by cleavage of tert-butyl groups using trifluoroacetic acid. Their copolymerization reactivity with 2-hydroxyethyl methacrylate (HEMA) investigated by photopolymerization studies performed on photo-differential scanning calorimetry shows higher reactivity of 2a compared to 1a. These crosslinkers are then used at different ratios for fabrication of pH- and redox-responsive poly(2-hydroxyethyl methacrylate)-based hydrogels. The swelling behavior of the hydrogels is found to be dependent on the structure of the crosslinker, degree of crosslinking, pH, and CaCl<sub>2</sub> concentration. The redox-responsive behavior is demonstrated by degradation of the hydrogel upon exposure to 1,4-dithiothreitol. The dye Rhodamine 6G and the drug resorcinol are used as models to demonstrate the pH and redox dependent release of loaded compounds from the hydrogels. The electrostatic interactions between the carboxylate groups and the positively charged R6G are found to govern the release profile in DTT and counteract the diffusion of dye molecules and significant amount of release (79% in 120 hr) occurs only at highly acidic conditions. The degradation mediated release in DTT is observed better in case of resorcinol (around 88% in 5 hr). Overall, these hydrogels can be regarded as good candidates for several applications, such as matrices for controlled release, tissue repair, and regeneration.
Is it usefull to test the final preparation after sperm washing?: Results from a highly reliable viral validation protocol of HIV processed semen by (RT)-nested PCR (2004)

info:eu-repo/semantics/nonPublished
Cricket (Acheta domesticus) protein hydrolysates’ impact on the physicochemical, structural and sensory properties of tortillas and tortilla chips (2020)

Consumer interest towards consumption of more sustainable protein sources has led way towards the adoption of insect protein for human food applications. Research shows that insect proteins utilised as food ingredients are more promising to be accepted by Westerners. In this study, cricket protein hydrolysates (CPH) were produced using Alcalase (AL) and Flavourzyme (FL) proteases. The physicochemical and structural properties, as well as the sensory acceptability of corn tortillas formulated with 20% (w/w) CPH were evaluated. CPH-tortillas contained all essential amino acids, including 40% of the daily lysine requirement. In raw corn masa (dough), AL-CPH increased the elastic modulus (G’), indicating cross-linking between polymers, while FL-CPH decreased G’. Tortillas formulated with AL-CPH resulted in matrices with low hardness and extensibility values, while FL-CPH tortillas developed a strong and flexible structure, indicating differences in intermolecular interactions between the AL- and FL-CPH and the tortilla matrix in the cooked tortillas compared to the raw masa. Sensory evaluation results showed acceptability (scores&gt;6.0) towards tortillas chips formulated with 20% CPH. Enzymatic hydrolysis of cricket protein can create peptides with functional characteristics and sensory acceptability for their use as ingredients in food formulation.
Il contributo della tecnologia nella gestione nel diabete tipo 1 (2022)

con l'implementazione del sistema delle televisite ma, dall'altro lato, ha aperto la possibilit a nuovi scenari assistenziali in cui la tecnologia diventata di preminente importanza, sia come sistema di interazione medico-paziente, sia come modalit di monitoraggio della glicemia e somministrazione della terapia.
Au-delà de la globalisation et du développement, société-monde ou empire-monde? (2002)

Cet article explore la question de l’identité en retraçant l’histoire artistique et personnelle de Giuseppina Pasqualino di Marineo, connue dans le monde entier sous le nom de Pippa Bacca, une artiste italienne originaire de Milan qui a été assassinée à l’âge de 34 ans en 2008 en Turquie lors de sa performance « Brides on tour ». C’est à travers l’analyse de la multiplicité des personnes présentes sur le parvis de l’église de San Simpliciano à Milano, réunies le jour de ses funérailles, qu’il sera possible de mieux comprendre la complexité et les multiples facettes de l’artiste et son importance dans le paysage culturel en Italie.
Magnetic and electronic transport properties of the novel compounds U2Co6Al19and Th2Co6Al19 (2004)

Experimental results on AC susceptibility, DC magnetization, electrical resistivity and magnetoresistivity up to 8 T have been obtained for a well annealed polycrystalline sample of the novel ternary aluminide U2Co6Al19. As a reference, similar experiments on the Th counterpart were also done. The U-containing aluminide exhibits two phase transitions at 8 and 12.5 K, probably of ferromagnetic and antiferromagnetic type, respectively. Moreover, U2Co6Al19 is a Kondo system showing the coherence effect below about 40 K. On the other hand, the Th counterpart showed unexpectedly a spin fluctuation behaviour, which was inferred from the broad maximum seen in its χ(T) dependence near 600 K. However, the low temperature variation of ρ(T) leads rather to an AT5/2 power dependence instead of to the AT2 one characteristic for a spin fluctuation behaviour.
Photochemistry and spectroscopy of monosubstituted derivatives of tungsten hexacarbonyl which exhibit low-efficiency photoreactivities (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhotochemistry and spectroscopy of monosubstituted derivatives of tungsten hexacarbonyl which exhibit low-efficiency photoreactivitiesR. Marc Dahlgren and Jeffrey I. ZinkCite this: J. Am. Chem. Soc. 1979, 101, 6, 1448–1454Publication Date (Print):March 1, 1979Publication History Published online1 May 2002Published inissue 1 March 1979https://pubs.acs.org/doi/10.1021/ja00500a014https://doi.org/10.1021/ja00500a014research-articleACS PublicationsRequest reuse permissionsArticle Views123Altmetric-Citations20LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Nonlinear Dynamics and Control of SDI Structural Components (1990)

Abstract : The report summarizes results of experimental and theoretical investigations into the nonlinear response and control of structural elements. Methods for the analysis and design of control procedures applicable to certain nonlinear distributed parameter systems were investigated. Analytical and computational techniques were developed for evaluating the nonlinear effects on control designs. Bench-type experiments were conducted for validating some of the theoretical results. Keywords: Nonlinear dynamics; Control; Resonances; Modal coupling.
Drifting walls (2014)

This chapter focuses on the learning that has emerged from a long-term collaborative design-led process that conjoins research, scholarly activity and design-based approaches. It provides a fuller description of the project, its background and drivers, followed by a discussion of the processes at the heart of the project. The project investigates the possibility of making hard things soft by combining textile and architectural thinking. The urge to collaborate on a project was quickly followed by the need to develop an agreed conceptual stance. The project began within the realm of free experimentation, i.e. ‘messing around’ with a range of materials to respond to the idea of ‘making hard things soft’. The technical challenges of the project have been multiple and have involved several phases. The project is hybrid on a variety of levels: hybrid because it brings together two diverse material cultures and their associated industries; and hybrid because it exists between academic and commercial worlds.
Modulation of HLA expression in human cytomegalovirus immune evasion. (2007)

Human cytomegalovirus (hCMV) has evolved multiple mechanisms to escape the host immune recognition and innate or adaptive immune responses. Among them, hCMV has developed strategies to modulate the expression and/or function of human leukocyte antigens (HLAs), including by encoding series of infection stage-dependent hCMV proteins to detain and destroy the expression of HLA molecules on the surface of infected cells. This disturbs the antigen presentation and processing, by encoding MHC class I homologues or selective up-regulation of particular HLA class I molecules binding to NK cell inhibitory receptors, and by encoding specific ligand antagonists to interfere with NK cell activating receptors. Here we discussed the molecular mechanisms utilized by the hCMV to alter the formation, transportation and expression of HLA antigens on the infected cell surface. The knowledge about hCMV modulating HLA expression could benefit us to further understand the pathogenesis of viral diseases and may eventually develop novel effective immunotherapies to counteract viral infections and viral associated diseases.
Empirical formula for rates of hot pixel defects based on pixel size, sensor area, and ISO (2013)

Experimentally, image sensors measurements show a continuous development of in-field permanent hot pixel defects increasing in numbers over time. In our tests we accumulated data on defects in cameras ranging from large area (&lt;300 sq mm) DSLR’s, medium sized (~40 sq mm) point and shoot, and small (20 sq mm) cell phone cameras. The results show that the rate of defects depends on the technology (APS or CCD), and on design parameters like imager area, pixel size (from 1.5 to 7 um), and gain (from ISO100 to 1600). Comparing different sensor sizes with similar pixel sizes has shown that defect rates scale linearly with sensor area, suggesting the metric of defects/year/sq mm, which we call <i>defect density</i>. A search was made to model this defect density as a function of the two parameters pixel size and ISO. The best empirical fit was obtained by a power law curve. For CCD imagers, the defect densities are proportional to the pixel size to the power of -2.25 times the ISO to the power of 0.69. For APS (CMOS) sensors the power law had the defect densities proportional to the pixel size to the power of -3.07 times the ISO raised to the power of 0.5. Extending our empirical formula to include ISO allows us to predict the expected defect development rate for a wide set of sensor parameters.
Association of the P6 Protein of Cauliflower mosaic virus with Plasmodesmata and Plasmodesmal Proteins (2014)

The P6 protein of Cauliflower mosaic virus (CaMV) is responsible for the formation of inclusion bodies (IBs), which are the sites for viral gene expression, replication, and virion assembly. Moreover, recent evidence indicates that ectopically expressed P6 inclusion-like bodies (I-LBs) move in association with actin microfilaments. Because CaMV virions accumulate preferentially in P6 IBs, we hypothesized that P6 IBs have a role in delivering CaMV virions to the plasmodesmata. We have determined that the P6 protein interacts with a C2 calcium-dependent membrane-targeting protein (designated Arabidopsis [Arabidopsis thaliana] Soybean Response to Cold [AtSRC2.2]) in a yeast (Saccharomyces cerevisiae) two-hybrid screen and have confirmed this interaction through coimmunoprecipitation and colocalization assays in the CaMV host Nicotiana benthamiana. An AtSRC2.2 protein fused to red fluorescent protein (RFP) was localized to the plasma membrane and specifically associated with plasmodesmata. The AtSRC2.2-RFP fusion also colocalized with two proteins previously shown to associate with plasmodesmata: the host protein Plasmodesmata-Localized Protein1 (PDLP1) and the CaMV movement protein (MP). Because P6 I-LBs colocalized with AtSRC2.2 and the P6 protein had previously been shown to interact with CaMV MP, we investigated whether P6 I-LBs might also be associated with plasmodesmata. We examined the colocalization of P6-RFP I-LBs with PDLP1-green fluorescent protein (GFP) and aniline blue (a stain for callose normally observed at plasmodesmata) and found that P6-RFP I-LBs were associated with each of these markers. Furthermore, P6-RFP coimmunoprecipitated with PDLP1-GFP. Our evidence that a portion of P6-GFP I-LBs associate with AtSRC2.2 and PDLP1 at plasmodesmata supports a model in which P6 IBs function to transfer CaMV virions directly to MP at the plasmodesmata.
Pulpal response to a new light-cured composite placed in etched glass-ionomer lined cavities. (1992)

This study evaluated the pulp biocompatability of a new light-cured composite resin which was placed in etched glass-ionomer-lined cavities of monkey teeth. The pulpal response to this material was less than that to zinc-oxide eugenol cement in each observation period. Therefore this material seems to meet acceptable biocompatability standards in nonhuman primates.
Molecular basis for the recently described hereditary hyperferritinemia- cataract syndrome: a mutation in the iron-responsive element of ferritin L-subunit gene (the "Verona mutation") [see comments] (1995)

Recently, we described a new genetic disorder (the "hereditary hyperferritinemia-cataract syndrome") clinically characterized by the combination of elevated serum ferritin and congenital bilateral nuclear cataract, both cotransmitted as an autosomal dominant trait. In affected subjects, hyperferritinemia (ranging from 950 to 2,259 micrograms/L) is typically not related to iron overload. Differently from subjects with hereditary hemochromatosis, they have normal to low levels of serum iron and percent of transferrin saturation and absence of iron overload in parenchymal organs. When unnecessary phlebotomies are performed, they rapidly develop iron-deficient anemia, with persistently elevated levels of serum ferritin. By RNA-single-strand conformation polymorphism screening of the L-subunit ferritin gene on chromosome 19, we were able to identify in affected subjects a mutation in the 5' untranslated region. This mutation involves the five nucleotides sequence [CAGUG] of the iron-responsive element (IRE), which is critical for the posttranscriptional regulation of ferritin synthesis by means of IRE-binding protein (IRE-BP). Thus, it is very likely to provide the molecular basis for the iron-insensitive upregulation of ferritin synthesis in affected subjects.
Recent Development of Anticancer Therapeutics Targeting Akt (2010)

The serine/threonine kinase Akt has proven to be a significant signaling target, involved in various biological functions. Because of its cardinal role in numerous cellular responses, Akt has been implicated in many human diseases, particularly cancer. It has been established that Akt is a viable and feasible target for anticancer therapeutics. Analysis of all Akt kinases reveals conserved homology for an N-terminal regulatory domain, which contains a pleckstrin-homology (PH) domain for cellular translocation, a kinase domain with serine/threonine specificity, and a C-terminal extension domain. These well defined regions have been targeted, and various approaches, including in silico methods, have been implemented to develop Akt inhibitors. In spite of unique techniques and a prolific body of knowledge surrounding Akt, no targeted Akt therapeutics have reached the market yet. Here we will highlight successes and challenges to date on the development of anticancer agents modulating the Akt pathway in recent patents as well as discuss the methods employed for this task. Special attention will be given to patents with focus on those discoveries using computer-aided drug design approaches.
Blood interference in fiber-optical based fluorescence guided resection of glioma using 5-aminolevulinic acid (2011)

Fluorescence guidance in brain tumor resection is performed intra-operatively where bleeding is included. When using fiber-optical probes, the transmission of light to and from the tissue is totally or partially blocked if a small amount of blood appears in front of the probe. Sometimes even after rinsing with saline, the remnant blood cells on the optical probe head, disturb the measurements. In such a case, the corresponding spectrum cannot be reliably quantified and is therefore discarded. The optimal case would be to calculate and take out the blood effect systematically from the collected signals. However, the first step is to study the pattern of blood interference in the fluorescence spectrum. In this study, a fiber-optical based fluorescence spectroscopy system with a laser excitation light of 405 nm (1.4 J/cm<sup>2</sup>) was used during fluorescence guided brain tumor resection using 5-aminolevulinic acid (5-ALA). The blood interference pattern in the fluorescence spectrum collected from the brain was studied in two patients. The operation situation was modeled in the laboratory by placing blood drops from the finger tip on the skin of forearm and the data was compared to the brain in vivo measurements. Additionally, a theoretical model was developed to simulate the blood interference pattern on the skin autofluorescence. The blood affects the collected fluorescence intensity and leaves traces of oxy and deoxy-hemoglobin absorption peaks. According to the developed theoretical model, the autofluorescence signal is considered to be totally blocked by an approximately 500 &#956;m thick blood layer.
Collaborative Behavior Models for Optimized Human-Robot Teamwork (2019)

Effective human-robot collaboration requires informed anticipation. The robot must anticipate the human's actions, but also react quickly and intuitively when its predictions are wrong. The robot must plan its actions to account for the human's own plan, with the knowledge that the human's behavior will change based on what the robot actually does. This cyclical game of predicting a human's future actions and generating a corresponding motion plan is extremely difficult to model using standard techniques. In this work, we describe a novel Model Predictive Control (MPC)-based framework for finding optimal trajectories in a collaborative, multi-agent setting, in which we simultaneously plan for the robot while predicting the actions of its external collaborators. We use human-robot handovers to demonstrate that with a strong model of the collaborator, our framework produces fluid, reactive human-robot interactions in novel, cluttered environments. Our method efficiently generates coordinated trajectories, and achieves a high success rate in handover, even in the presence of significant sensor noise.