gebhart/patrepeval huggingface dataset:
Insulin-like growth factor binding protein profiles in human ovarian follicular fluid correlate with follicular functional status (1992)

The insulin-like growth factors (IGF), IGF-I and IGF-II, influence ovarian follicular development. The IGF binding proteins (IGFBPs) comprise at least six distinct species which may modulate IGF action. We examined IGFBP profiles in follicular fluid (FF) from developing human ovarian follicles with aromatase activity as well as from androgen-dominant, atretic follicles. Western ligand blot analysis of FF from both atretic and active follicles revealed the presence of IGFBP-3 and IGFBP-2, confirmed by immunoprecipitation with specific antiserum, as well as 28 kilodalton (kDa) and 24 kDa IGFBPs. In FF specimens obtained during the follicular phase, IGFBP-2 and the 28 kDa and 24 kDa species were present in 3-, 6-, and 19-fold higher amounts in atretic compared to healthy developing follicles, respectively, and were present in greater amounts in atretic FF than in serum. In atretic FF obtained during the luteal phase, lower levels of IGFBP-2 and the 28 and 24 kDa IGFBPs were seen than in atretic follicles in the follicular phase. IGFBP-3 levels were comparable in all types of follicles and in serum. The 28 kDa IGFBP is glycosylated, and its level varied in parallel with the 24 kDa IGFBP, suggesting that these are variants of the recently identified IGFBP-4. IGFBP-1 was not detectable by immunoprecipitation and ligand blotting of FF obtained during the follicular phase. These data suggest that one or more IGFBPs present in higher levels in FF from atretic compared to healthy, developing follicles may play an important role in folliculogenesis and follicular atresia.
The Influence of the Phase Morphology on the Optoelectronic Properties of Light‐Emitting Electrochemical Cells (2004)

Abstract We report on the morphological aspects of thin films prepared from a blue–green light‐emitting conjugated polymer, (methyl‐substituted ladder‐type poly( p ‐phenylene, mLPPP)), blended with a solid‐state electrolyte composed either by a crown ether, dicyclohexano‐18‐crown‐6 (DCH18C6), or a high‐molecular‐weight poly(ethylene oxide) (HMWPEO), and a Li salt, lithium trifluoromethanesulfonate (LiCF 3 SO 3 , Li triflate (LiTf)), as they have been successfully applied in light‐emitting electrochemical cells (LECs). The surface morphologies of the blend layers were investigated using atomic force microscopy (AFM) in tapping mode, and the ion distribution was probed using X‐ray analysis by means of energy‐dispersive X‐ray spectrometry (EDXS) in the scanning electron microscope (SEM). We show that the two different phase‐separation processes, the complexation tendencies of the ionic species as well as the ionic transport numbers, have tremendous influence on the performances of the corresponding LECs, revealing either rectifying or symmetric optoelectronic characteristics in forward and reverse bias directions. This opens up new possibilities for tuning the optoelectronic properties of ion‐supported organic electronic devices.
Trace2au - Audio Monitoring Tools for Parallel Programs (1993)

It is not easy to reach the best performances you can expect of a parallel computer. We therefore have to use monitoring programs to study the performances of parallel programs. We introduce here a way to generate sound in real-time on a workstation, with no additional hardware, and we apply it to such monitoring programs. Keywords: Monitoring, Parallelism, Sound on a workstation, Sonification 1 Introduction Monitoring the behavior and performances of massively parallel programs has proved to be quite difficult. We have to deal with two major problems: gathering the monitoring data and using it to understand the behavior of the studied parallel program to, hopefully, increase its performances. This paper will focus on the latter problem. More precisely, we will see how sound can be generated in real-time 1 on a workstation, and used to extract relevant information from the monitoring trace files. We therefore suppose that the monitoring data is already available, and that we have on...
Electronic and Transport Properties of Epitaxial Graphene on SiC and 3C-SiC/Si: A Review (2020)

The electronic and transport properties of epitaxial graphene are dominated by the interactions the material makes with its surroundings. Based on the transport properties of epitaxial graphene on SiC and 3C-SiC/Si substrates reported in the literature, we emphasize that the graphene interfaces formed between the active material and its environment are of paramount importance, and how interface modifications enable the fine-tuning of the transport properties of graphene. This review provides a renewed attention on the understanding and engineering of epitaxial graphene interfaces for integrated electronics and photonics applications.
Diagnostic and Therapeutic Management of a First Unprovoked Seizure in Children and Adolescents With a Focus on the Revised Diagnostic Criteria for Epilepsy (2017)

By definition, unprovoked seizures are not precipitated by an identifiable factor, such as fever or trauma. A thorough history and physical examination are essential to caring for pediatric patients with a potential first unprovoked seizure. Differential diagnosis, EEG, neuroimaging, laboratory tests, and initiation of treatment will be reviewed. Treatment is typically initiated after 2 unprovoked seizures, or after 1 seizure in select patients with distinct epilepsy syndromes. Recent expansion of the definition of epilepsy by the ILAE allows for the diagnosis of epilepsy to be made after the first seizure if the clinical presentation and supporting diagnostic studies suggest a greater than 60% chance of a second seizure. This review summarizes the current literature on the diagnostic and therapeutic management of first unprovoked seizure in children and adolescents while taking into consideration the revised diagnostic criteria of epilepsy.
Produktionsplanung und ihre Stellung innerhalb der Unternehmensplanung (1988)

Der Produktionsplan muß neben Angaben über das zu produzierende Leistungsprogramm aber auch Anweisungen für die Durchführung der Produktion enthalten, d.h., es ist zu bestimmen, wann unter Einsatz welcher Produktionsfaktoren welche Leistungen zu erstellen sind. Die Produktionsplanung hat damit die Frage zu beantworten, was wann unter Einsatz welcher Faktoren (wie) produziert werden soll.
Suzuki cross-coupling reactions of aryl halides in phosphonium salt ionic liquid under mild conditions (2002)

The Suzuki cross-coupling of aryl boronic acids with aryl halides, including aryl chlorides, proceeds in the phosphonium salt ionic liquid tetradecyltrihexylphosphonium chloride under mild conditions.
Percutaneous balloon mitral valvuloplasty in rheumatic mitral stenosis: An experience of 50 patients in india (1991)

We attempted percutaneous balloon mitral valvuloplasty in 50 patients (27 female and 23 male, age 10-38 years) with rheumatic mitral stenosis. The procedure could be completed in 40 patients. The failures were caused by problems related to transseptal puncture in eight cases and inability to cross the mitral valve in two cases. Immediately after valvuloplasty there was a remarkable reduction in the mean pulmonary artery pressure, left atrial mean pressure, mean diastolic gradient across the mitral valve, and the calculated pulmonary vascular resistance. The calculated mitral valve area increased and the cardiac index increased marginally. Inadequate results with a post valvuloplasty mitral valve area of 0.9 cm2 were seen in only one patient. Repeat hemodynamic evaluation in 25 patients within two weeks of valvuloplasty showed persistent benefit in all except one patient, who showed partial restenosis. Follow-up cardiac catheterization at 3-6 months in 13 patients showed evidence of restenosis (mitral valve area less than 1.0 cm2 and mean diastolic gradient of greater than 10 mmHg) in one patient, while all others maintained hemodynamic benefit. Repeat hemodynamic evaluation at 9-18 months after valvuloplasty in eight patients showed evidence of restenosis in an additional two cases. The patients in our series are young (28 patients less than 20 years), small body surface area (1.35-0.2 m2), and have high left atrial and pulmonary arterial pressures.
Patient with chronic kidney disease after heart transplantation due to severe chronic heart failure (2012)

W pracy przedstawiono przypadek 55-letniego mezczyzny zakwalifikowanego do przeszczepienia serca w trybie elektywnym z powodu ciezkiej niewydolności serca na podlozu kardiomiopatii niedokrwiennej i z przewleklą chorobą nerek, ktorego hospitalizowano z powodu zaostrzenia niewydolności serca. Po początkowym ustabilizowaniu stanu hemodynamicznego u chorego doszlo do naglego zatrzymania krązenia. Po skutecznej resuscytacji pacjenta przekazano do Kliniki Kardiochirurgii GUMed w celu leczenia urządzeniem wspomagającym prace komor i po 70 dniach wykonano u niego przeszczepienie serca. Po przeszczepieniu nastąpilo pogorszenie funkcji nerek. W pracy omowiono mozliwe przyczyny pogorszenia funkcji nerek u pacjentow poddawanych przeszczepieniu serca.
Bactericidal Effect of Sodium Chlorate on Escherichia coli Concentrations in Bovine Ruminal and Fecal Contents In Vivo (2002)

Enterohemorrhagic Escherichia coli causes a potentially fatal disease in humans. Since human infections often occur following consumption of contaminated meat, strategies are sought to rid these pathogens from food-producing animals. E. coli, like most members of the family Enterobacteriaceae, possess respiratory nitrate reductase, an enzyme that coincidentally reduces chlorate to toxic chlorite. Consequently, a study was performed to assess the effect of intraruminal chlorate administration on E. coli in the gut of fed and fasted cattle, the latter having been reported to harbor increased concentrations of enteric pathogens. As hypothesized, E. coli concentrations were lower ( p <0.05) 10 and 24 h post chlorate administration, respectively, in rumen contents and feces of chlorate-treated cows than in untreated cows. Fasting had little effect on gut E. coli concentrations and did not effect the bactericidal effect of chlorate against E. coli. Chlorate treatment had little or no effect on fermentation efficiency, as evidenced by pH, volatile fatty acid production and concentration of total culturable anaerobes, and had no observable adverse effects on any of the cows. These results suggest that chlorate may be useful in the pre-harvest control of E. coli.
Precision Grinding of Structured Tungsten Carbide Mold (2012)

Demands of glass Fresnel lens is increasing in solar panel in order to increase power efficiency. Glass lens is usually molded by glass molding method with tungsten carbide molds. In this study, large Fresnel lens molds made of tungsten carbide are tested to be ground by simultaneous 2-axis (Y, Z) controlled grinding method. The resinoid bonded diamond wheel was trued with a rare metal truer to improve the sharpness of the wheel edge. In the grinding test of the tungsten carbide mold, a form accuracy of less than 0.8 μm P-V and surface roughness of 18 nm Rz were obtained, and it is clarified that the proposed grinding method is useful for the Fresnel grinding.
An Acquisition Scheme Based on a Matched Filter for Novel Communication and Navigation Fusion Signals (2017)

In order to enhance the positioning capability of terrestrial networks, a novel communication and navigation fusion signal is proposed. The novel signal multiplexes the communication and navigation signal in the same frequency band, and the navigation system is superimposed on the original communication system. However, the application of pseudorandom noise (PRN) sequences in the navigation system is limited by the communication clock period. Taking the application of PRN sequences limited by the clock period as objects, the present study analyzes truncated PRN (TPRN) sequences. PRN sequences with a TPRN sequence as the navigation signal can overcome the communication system clock period limitation. Then, a matched filter algorithm with double detection (MFADD) is proposed to acquire the novel signal. The matched filter method is applied to the proposed algorithm to determine the start code phase of TPRN. Monte Carlo simulations and real data tests demonstrate the effectiveness of the proposed algorithm for the designed signal.
Does folic acid and zinc sulphate intervention affect endocrine parameters and sperm characteristics in men? (2005)

We evaluated pre- and post-intervention endocrine and semen parameters in a double-blind, placebo-controlled intervention study to investigate the underlying mechanism of increased sperm concentration after folic acid and zinc sulphate intervention. A total of 47 fertile and 40 subfertile males participated in a 26-week intervention study consisting of a daily treatment with folic acid (5 mg/day) and zinc sulphate (66 mg/day), or placebo. Pre- and post-intervention semen parameters, serum folate, zinc, follicle-stimulating hormone (FSH), testosterone and inhibin B concentrations were measured. The results indicated that intervention treatment significantly increased sperm concentration in subfertile males. Other semen and endocrine parameters were not affected by intervention treatment. At baseline, positive correlations were found between serum zinc and sperm concentration, motility and inhibin B. Serum zinc and FSH were inversely correlated. As (already) well known from previous research, inhibin B positively correlated with sperm concentration, motility and morphology, and was inversely correlated with FSH. The latter was positively correlated with testosterone. In addition, testosterone and inhibin B were inversely correlated. After intervention, the correlations with zinc disappeared. We conclude that the increase in sperm concentration after folic acid and zinc sulphate intervention is not the result of alterations in FSH, testosterone or inhibin B concentrations. Although zinc and folate have several effects on spermatogenesis, the underlying mechanisms involved are not clear.
PEPC‐mediated carbon fixation in transmitting tract cells reflects style–pollen tube interactions (1992)

Summary Styles nurture and guide pollen tubes to the ovules. The styles of Nicotiana tabacum , a C 3 plant, contain a concentric strand of transmitting tract cells replete with well‐developed chloroplasts. It is shown that the chloroplasts have normal ultrastructure and electron transport ability. However, they were found to be devoid of Rubisco, the key enzyme responsible for carbon fixation in C 3 plants. Nevertheless, non‐invasive fluorescence techniques showed a light‐driven photosynthetic flux. Carbon fixation via phosphoenol pyruvate carboxylase (PEPC) into malate was demonstrated, the latter accumulating during stylar development. Characterization of stylar PEPC in vitro and in vivo revealed apparent K m values consistent with bicarbonate as a rate limiting factor for photosynthetic flux. Presumably, in the closed confines of the intact style, respired CO 2 is the source of carbonate. Enhanced photosynthetic flux was detected following pollination, suggesting utilization of the additional respired bicarbonate and underlining metabolic interactions between the style and the elongating pollen tube.
AmbiSep: Ambisonic-to-Ambisonic Reverberant Speech Separation Using Transformer Networks (2022)

Consider a multichannel Ambisonic recording containing a mixture of several reverberant speech signals. Retrieving the reverberant Ambisonic signals corresponding to the individual speech sources blindly from the mixture is a challenging task as it requires estimating multiple signal channels for each source. In this work, we propose AmbiSep, a deep neural network-based plane-wave domain masking approach to solve this task. The masking network uses learned feature representations and transformers in a triple-path processing configuration. We train and evaluate the proposed network architecture on a spatialized WSJ0-2mix dataset and show that the method achieves a multichannel scale-invariant signal-to-distortion ratio improvement of 17.7 dB on the blind test set while preserving the spatial characteristics of the separated sounds.
The Smiling Project: Development Of A New Program For Gait And Balance Training (2010)

Introduction: The SMILING project, a multicentric project fundedby the European Union, aims to develop a new gait and balance trainingprogram to prevent falls in older persons. The program includes the"SMILING shoe", an innovative device that generates mechanical perturbationwhile walking by changing the soles' inclination. Induced perturbationschallenge subjects' balance and force them to react to avoidfalls. By training specifically the complex motor reactions used to maintainbalance when walking on irregular ground, the program will improvesubjects' ability to react in situation of unsteadiness and reduce theirrisk of falling. Methods: The program will be evaluated in a multicentric,cross-over randomized controlled trial. Overall, 112 subjects (aged≥65 years, ≥1 falls, POMA score 22-26/28) will be enrolled. Subjectswill be randomised in 2 groups: group A begin the training with active"SMILING shoes", group B with inactive dummy shoes. After 4 weeksof training, group A and B will exchange the shoes. Supervised trainingsessions (30 minutes twice a week for 8 weeks) include walkingtasks of progressive difficulties.To avoid a learning effect, "SMILINGshoes" perturbations will be generated in a non-linear and chaotic way.Gait performance, fear of falling, and acceptability of the program willbe assessed. Conclusion: The SMILING program is an innovative interventionfor falls prevention in older persons based on gait and balancetraining using chaotic perturbations. Because of the easy use of the"SMILING shoes", this program could be used in various settings, suchas geriatric clinics or at home.
Confocal microwave imaging for breast tumor detection: comparison of immersion liquids (2002)

Microwave imaging for breast cancer has been proposed as an alternative or complementary breast imaging technique. The physical basis for tumor detection with microwave imaging is the contrast in dielectric properties of normal and malignant breast tissue. One approach to active microwave imaging of the breast is confocal microwave imaging (CMI). CMI locates tumors using energy reflected from the breast after illumination by an ultra-wideband signal. In one configuration for CMI, a woman lies on her stomach with the breast naturally extending through a hole in the examination table. The illuminating antenna is positioned at a distance from the skin, and physically scanned to a number of locations. Both the antenna and breast are immersed in a low loss liquid for better matching. Previously, our investigations focussed on detection and localization of tumors in a 2D cross section of a simple breast model. We now present 3D localization of tumors achieved with 2 different immersions liquids, one similar to breast tissue and the other similar to skin. For both systems, a 6 mm diameter tumor is reliably detected and localized in 3D. The results do not indicate a clear advantage to selecting either liquid.
Studies of binding of prekallikrein and Factor XI to high molecular weight kininogen and its light chain. (1979)

Prekallikrein and Factor XI have been reported to circulate as complexes with the coagulation cofactor high molecular weight (HMW)-kininogen. In this study we have shown that native HMW-kininogen possesses a strong binding site for prekallikrein and Factor XI with association constants of 3.4 x 10(7) M-1 and 4.2 x 10(8) M-1, respectively. The diminished binding of prekallikrein relative to Factor XI may, in part, account for the ability of kallikrein to leave the surface and interact with other molecules of Hageman factor and HMW-kininogen. Prekallikrein and Factor XI appear to compete for binding to HMW-kininogen, suggesting a single (or closely overlapping) binding site(s). The purified light chain derived from kinin-free HMW-kininogen is shown to compete with native MHW-kininogen for binding to Hageman factor substrates and direct binding of the isolated light chain to prekalikrein and Factor XI is demonstrated. This binding of the light chain to prekallikrein and Factor XI appears to be essential to the function of HMW-kininogen as a coagulation cofactor and further digestion of the light chain with excess kallikrein destroys its coagulant activity.
Variable rate particle filters for tracking applications (2005)

Here we describe recent advances in particle filtering algorithms and models for tracking of manoeuvring objects in clutter. The methods develop on the basic variable dimension particle filtering algorithms introduced in S.J. Godsill and J. Vermaak (2004), in which a new type of dynamical model is introduced whose state variables arrive at unknown times relative to the observation process (hence 'variable rate'). Targets are assumed to follow deterministic trajectories in between state times, determined by an appropriate model, such as the differential equation model for the object. The framework allows for automatic modelling and estimation of the trajectories of targets using an adaptation of particle filtering methods (A. Doucet et al., 2000) into the variable dimension setting. In this paper we introduce more effective sampling schemes for the variable rate setting that ensure future states are only generated as and when required, new dynamical models appropriate for manoeuvring objects, and new observation models under the assumption of a nonhomogeneous Poisson process for both targets and clutter. Simulations show very effective tracking performance under challenging settings which cannot be emulated in a standard fixed rate scheme
Wormhole: reliable pub-sub to support geo-replicated internet services (2015)

Wormhole is a publish-subscribe (pub-sub) system developed for use within Facebook's geographically replicated datacenters. It is used to reliably replicate changes among several Facebook services including TAO, Graph Search and Memcache. This paper describes the design and implementation of Wormhole as well as the operational challenges of scaling the system to support the multiple data storage systems deployed at Facebook. Our production deployment of Wormhole transfers over 35 GBytes/sec in steady state (50 millions messages/sec or 5 trillion messages/day) across all deployments with bursts up to 200 GBytes/sec during failure recovery. We demonstrate that Wormhole publishes updates with low latency to subscribers that can fail or consume updates at varying rates, without compromising efficiency.
Breakfast at Tiffany's? Only with a low‐abundance proteomic signature! (2012)

Food science is a complex domain where modern analytical technologies interact with each other. Named as "Foodomics," this domain assembles a variety of investigational fields such as genomics, transcriptomics, proteomics, peptidomics, and metabolomics. All these technologies are at the service of several goals that are essentially dictated by fundamental understanding, safety, and consistency. In this report, open questions are summarized around proteins and selected technologies recommended for a proper analytical determination not only of composition, but also considering the low-abundance expressed species difficult to detect for their presence, their function, and their adverse effects such as allergic action. In particular, this review covers the proteome of foodstuff and beverages, as detected via combinatorial peptide ligand libraries, such as: bovine and donkey's milk, egg white, and yolk, white and red wine, beer, and a number of nonalcoholic beverages, such as almond's milk and orgeat syrup, Cola, ginger ale, and vinegar.