gebhart/patrepeval huggingface dataset:
A Propensity Score Matched Study of the Positive Impact of Infectious Diseases Consultation on Antimicrobial Appropriateness in Hospitalized Patients with Antimicrobial Stewardship Oversight (2020)

Hospital-based antibiotic stewardship (AS) programs provide oversight and guidance for appropriate antimicrobial use in acute care settings. Infectious disease expertise is beneficial in the care of hospitalized patients with infections. The impact of infectious diseases consultation (IDC) on antimicrobial appropriateness in a large tertiary hospital with an established AS program was investigated. This was a cross-sectional study from October 2017 to March 2019 at a large academic hospital with an AS-directed prospective audit and feedback process and multiple IDC services. Antimicrobial appropriateness was adjudicated by an AS team member after antimicrobial start. Antimicrobial appropriateness was compared among antimicrobial orders with and without IDC using propensity score matching and multivariable logistic regression. Analyses were stratified by primary services caring for the patients. There were 10,508 antimicrobial orders from 6,165 unique patient encounters. Overall appropriateness was 92%, with higher appropriateness among patients with IDC versus without IDC (94% versus 84%; <i>P</i> < 0.0001). After propensity score matching and adjustment for certain antibiotics, organisms, syndromes, and locations, IDC was associated with a greater antimicrobial appropriateness odds ratio (OR) of 2.4 (95% confidence interval [CI], 1.9 to 3.0). Stratification by primary service showed an OR of 2.9 (95% CI, 2.1 to 3.8) for surgical specialties and an OR of 1.6 (95% CI, 1.1 to 2.2) for medical specialties. Even with a high overall antimicrobial appropriateness, patients with IDC had greater odds of antimicrobial appropriateness than those without IDC, and this impact was greater in surgical specialties. Infectious diseases consultation can be synergistic with antimicrobial stewardship programs.
A conductive polymer coated MoO3anode enables an Al-ion capacitor with high performance (2016)

The feasibility of assembling an Al-ion capacitor with good electrochemical performance is demonstrated. Preliminary results indicate that the fabricated Al-ion capacitor could reversibly cycle in the voltage region of 0–1.5 V and display intriguing performances with an energy density of 30 W h kg<sup>−1</sup>.
Occurrence of Cerium-, Titanium-, and Silver-Bearing Nanoparticles in the Besòs and Ebro Rivers (2020)

The presence of anthropogenic nanoparticles (NPs) in the aquatic environment has become an emerging concern in terms of environmental and health safety. In the present study, we assessed the presence of Ag-bearing, Ti-bearing, and Ce-bearing NPs in the Barcelona catchment area, including the Besòs River basin and the Barcelona coast, and in the Ebro River Delta, using single particle inductively coupled plasma mass spectrometry (sp-ICP-MS). Ti-NPs and Ce-NPs were ubiquitously detected in surface waters, and their presence was related to a high natural background. Concentrations of Ti-NPs ranged from 23.2 × 10<sup>6</sup> to 298 × 10<sup>6</sup> Ti-NPs/L, with high concentrations being detected in areas with little anthropogenic pressure, while the presence of nanosilver (17.9 × 10<sup>6</sup> to 45.1 × 10<sup>6</sup> Ag-NPs/L) in the analyzed rivers was limited to certain hotspots close to wastewater treatment plants discharge points. The concentrations of Ce-NPs in the river ranged from 18.1 × 10<sup>6</sup> to 278 × 10<sup>6</sup> NPs/L, and they were related to the natural occurrence of the mineral Monazite-(Ce). Overall, the concentrations of these nanomaterials in the Barcelonan coast were significantly attenuated by river-sea environmental dilution. Nevertheless, Ce-NPs were eventually detected in some seawater samples with low levels of lanthanum-NPs, suggesting anthropogenic inputs of nanoCeO<sub>2</sub>, probably from atmospheric deposition.
Fault-tolerant real-time communication in distributed computing systems (2003)

An increasing number of applications require packets to be delivered reliably within prespecified delay bounds. It is shown how this can be achieved by using real-time channels that make soft reservation of network resources to ensure the timely delivery of real-time packets. Algorithms are presented for the establishment of real-time channels, and it is shown how the basic real-time channels can be enhanced to be fault tolerant using the multiple paths between a pair of communicating nodes. The contribution of the former is a tighter schedulability condition that makes more efficient use of network resources than other existing approaches, and the contribution of the latter is a significant improvement in fault tolerance over the basic real-time channel, which is inherently susceptible to component failures.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
PROGRESS IN ORTHOPEDIC SURGERY FOR 1943 A REVIEW PREPARED BY AN EDITORIAL BOARD OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS (1944)

<h3>Injuries to Nerves.</h3> —In this series of disorders are included injuries in or about the shoulder girdle due to a variety of causes. Hauser and Martin<sup>106</sup>present 2 additional cases of winged scapula occurring in the armed forces; in 1 case the condition resulted from repeated lifting of heavy objects and in the other from an automobile accident. In both there was isolated paralysis of the serratus anterior muscle. Burnard and Fox<sup>107</sup>present 9 cases of multiple neuritis of the shoulder girdle resulting from various causes which occurred in the second New Zealand Expeditionary Force. Clausen<sup>108</sup>reviews the literature and reports 9 cases of postoperative or anesthetic paralysis of the brachial plexus. Ramirez<sup>109</sup>reports several cases of brachial paralysis following the administration of serum. Saksena<sup>110</sup>reports paralysis of the serratus anterior muscle following glandular fever. <h3>Ed. Note.</h3> —This series of papers is especially interesting because
Tunable Narrow-Bandwidth Optical Filter Based on Acoustically Modulated Fiber Bragg Grating (2004)

We demonstrate a novel tunable narrow-bandwidth optical filter based on an acoustically modulated fiber Bragg grating (FBG). A flexural acoustic wave applied to an off-centered core FBG modulates the period of the grating, producing sidebands tunable both in wavelength and magnitude.
Electrical Heat Tracking: International Harmonization — Now and in the Future (2002)

In the past, electrical heat tracing has been thought of as a minor addition to plant utilities. Today, it is recognized as a critical subsystem to be monitored and controlled. A marriage between process, mechanical, and electrical engineers must take place to ensure that optimum economic results are produced. The Internet, expert systems, and falling costs of instrumentation will all contribute to more reliable control systems and improved monitoring systems. There is a harmonization between Europe and North America that should facilitate design and installation using common components. The future holds many opportunities to optimize the design.
Growth of Single Domain GaAs on 2-inch Si(100) Substrate by Molecular Beam Epitaxy (1985)

Good surface morphological single domain GaAs films were successfully grown on a whole area of 2-inch Si(100) substrates by molecular beam epitaxy (MBE). Si substrates were first thermally cleaned at 850°C, 100 Å GaAs buffer layers were then grown at low substrate temperatures and, finally, 1.5 µm GaAs layers were grown at 600°C. It was found that the first thermal cleaning of Si is important in growing single domain GaAs and the growth temperatures of the buffer layer had to be low to get a good morphological surface.
A New Model for Studying the Revascularization of Skin Grafts In Vivo: The Role of Angiogenesis (2008)

This new model allows for repetitive analysis of the microcirculation during skin graft healing. It provides ideal in vivo conditions to further delineate the exact mechanisms of blood vessel interconnection during the complex process of angiogenesis, and may also allow study of the vascularization of tissue-engineered skin substitutes.
Neuroprotective Properties of the Benzodiazepine Receptor, Partial Agonist PNU-101017 in the Gerbil Forebrain Ischemia Model (1997)

PNU-101017 is a novel, imidazoquinoline amide and benzodiazepine receptor partial agonist that has high affinity for the GABAA receptor subtypes containing the alpha 1 and alpha 3 or alpha 5 subunits. At each of these receptors, the compound is a partial agonist with approximately 50% of the intrinsic activity of the full agonist diazepam. In view of the previously demonstrated anti-ischemic effects of some GABA agonists, the purpose of this study was to determine the ability of PNU-101017 to salvage selectively vulnerable neuronal populations in the gerbil forebrain ischemia model. In an initial set of experiments, male gerbils were pretreated 30 minutes before ischemia induction (5 minutes) with PNU-101017 (3, 10, or 30 mg/kg intraperitoneally) and again 2 hours after reperfusion. In vehicle (0.05 N HC1)-treated gerbils, the loss of hippocampal CA1 neurons at 5 days was 80%. PNU-101017 was shown to produce a dose-related increase in CA1 neuronal survival; at either 10 or 30 mg/kg, the loss of CA1 neurons was only 21% (P < 0.005 versus vehicle). A second experiment, examined the therapeutic window for PNU-101017 using the dose level of 30 mg/kg intraperitoneally. Administration of the first of two doses (2 hours apart) at the time of reperfusion resulted in an identical decrease in CA1 damage at 5 days to that seen with preischemic treatment (P < 0.003 versus vehicle). Even with a delay of the initial dosing until 4 hours after reperfusion, PNU-101017 reduced CA1 neuronal loss to only 32% (P < 0.01 versus vehicle). In a third experiment in which the duration of the ischemic insult was increased to 10 minutes and the brains were not analyzed until 28 days after ischemia, daily PNU-101017 dosing for the full 28 days still significantly preserved CA1 neurons, although less effectively than in the milder 5 minute-ischemia model. The loss of dopaminergic nigrostriatal neurons was also reduced. The neuroprotective effect of PNU-101017 was not associated with any overt CNS depression and it did not correlate with hypothermia. This benzodiazepine-receptor partial agonist may have potential for the treatment of global cerebral ischemia.
Synthesis and Catalytic Evaluation of Ruthenium–Arene Complexes Bearing Imidazol(in)ium-2-thiocarboxylate Ligands (2011)

Five new complexes with the generic formula [RuCl2(p-cymene)(SOC·NHC)] (2–6) were isolated in high yields by reacting the [RuCl2(p-cymene)]2 dimer with a range of imidazol(in)ium-2-thiocarboxylate zwitterions bearing cyclohexyl, 2,4,6-trimethylphenyl (mesityl), or 2,6-diisopropylphenyl groups on their nitrogen atoms in CH2Cl2 at −20 °C. All the products were fully characterized by IR and NMR spectroscopy, and the molecular structures of [RuCl2(p-cymene)(SOC·IMes)] (3) and [RuCl2(p-cymene)(SOC·SIMes)] (5) were determined by X-ray diffraction analysis. Coordination of the NHC·COS ligands took place via the sulfur atom. A remarkable shielding of the methine proton on the p-cymene isopropyl group was observed by 1H NMR spectroscopy for complexes 3–6. It is most likely caused by the aromatic ring current of a neighboring mesityl or 2,6-diisopropylphenyl substituent. The catalytic activity of compounds 2–6 was probed in the ring-opening metathesis polymerization (ROMP) of cyclooctene, in the atom transfer radical polymerization (ATRP) of methyl methacrylate, and in the synthesis of enol esters from 1-hexyne and 4-acetoxybenzoic acid. In all these reactions, the [RuCl2(p-cymene)(SOC·NHC)] complexes displayed performances slightly inferior to those exhibited by [RuCl2(p-cymene)(NHC)] species that result from the reaction of [RuCl2(p-cymene)]2 with NHC·CO2 inner salts. However, they were significantly better catalyst precursors than the much more robust chelates of the [RuCl(p-cymene)(S2C·NHC)]PF6 type obtained by coordination of NHC·CS2 betaines to the ruthenium dimer. These results suggest that the Ru–(SOC·NHC) motif undergoes a dethiocarboxylation under the experimental conditions adopted for the catalytic tests and leads to the same elusive Ru–NHC active species as the preformed [RuCl2(p-cymene)(NHC)] family of complexes.
Asymmetrical Myelination of the Posterior Limb of the Internal Capsule in Infants with Periventricular Haemorrhagic Infarction: An Early Predictor of Hemiplegia (1999)

While a symmetrical signal intensity within the internal capsule on MRI, performed at 40 weeks PMA, in infants with an IVH and unilateral PI appears to be strongly related to a normal outcome, an asymmetrical PLIC is an early predictor of future hemiplegia.
Thermal decay of UV Ar+ and ArF excimer laser fabricated Bragg gratings in SMF-28e and Bi-Al-doped optical fiber (2012)

Fiber Bragg Gratings fabricated in pristine Bi-Al-SiO2 and SMF-28e fibers using pulsed ArF-excimer and cw-244-nm Ar+ laser were annealed. Gaussian decomposition of the master curves revealed energy distributions depending on fiber and laser used.
Engineering Mechanics of Composite Materials (1994)

Engineering Mechanics of Composite Materials, 2/e analyzes the behavior and properties of composite materials-rigid, high-strength, lightweight components that can be used in infrastructure, aircraft, automobiles, biomedical products, and a myriad of other goods. This edition features additional exercises and new material based on the author's research and advances in the field.
Peritoneal Fluid Transport rather than Peritoneal Solute Transport Associates with Dialysis Vintage and Age of Peritoneal Dialysis Patients (2016)

During peritoneal dialysis (PD), the peritoneal membrane undergoes ageing processes that affect its function. Here we analyzed associations of patient age and dialysis vintage with parameters of peritoneal transport of fluid and solutes, directly measured and estimated based on the pore model, for individual patients. Thirty-three patients (15 females; age 60 (21-87) years; median time on PD 19 (3-100) months) underwent sequential peritoneal equilibration test. Dialysis vintage and patient age did not correlate. Estimation of parameters of the two-pore model of peritoneal transport was performed. The estimated fluid transport parameters, including hydraulic permeability (LpS), fraction of ultrasmall pores (α u), osmotic conductance for glucose (OCG), and peritoneal absorption, were generally independent of solute transport parameters (diffusive mass transport parameters). Fluid transport parameters correlated whereas transport parameters for small solutes and proteins did not correlate with dialysis vintage and patient age. Although LpS and OCG were lower for older patients and those with long dialysis vintage, αu was higher. Thus, fluid transport parameters--rather than solute transport parameters--are linked to dialysis vintage and patient age and should therefore be included when monitoring processes linked to ageing of the peritoneal membrane.
Transgenic Plant Production from Embryogenic Callus of Sweet Potato (Ipomoea batatas (L.) Lam.) Using Agrobacterium tumefaciens (1998)

Transformed sweet potato plants were obtained from embryogenic calli following Agrobacterium tumefaciens-mediated transformation. A. tumefaciens strain EHA101/pIG121-Hm used in the present study contained a binary vector with genes for β-glucuronidase (gusA) and hygromycin resistance (hpt). Around ten hygromycin resistant cell clusters were produced from 1g fresh weight of the infected embryogenic calli. The hygromycin resistant plantlets were regenerated from 53.1% of the hygromycin-resistant calli. Histochemical GUS assay and Southern hybridization analysis indicated that these plants were stably transformed with a copy number of introduced genes of one to three. Transgenic plants grew normally and formed storage roots after 3 months of cultivation in a green house.
Multichannel edge-enhancing technique (1992)

In this paper, a multichannel edge enhancing filter (MEEF) applied to color image processing is proposed to improve the degraded edges in color TV picture which are classified as the following cases: the blurred edges caused by unfocusing or fast shift of camera, the serrated edges caused by interlaced scanning, and the chroma-cross edges caused by channel dispersion Because of a high between-channel dependence in color image, individual edge enhancement in each channel is not a natural method without utilizing between-channel dependence. Thus, this technique is not recommended in color image processing. The proposed MEEF is successfully used in dealing with this sort of the degraded edges of multichannel image. The root signals and edge enhancement properties of MEEF are investigated in detail. The experimental results show that MEEF outperforms independent edge enhancing filter in improving the degraded edges caused by unfocusing, interlaced scanning and channel dispersion.
Power-aware communication for wireless sensor-actuator systems (2013)

This paper considers the design of power-aware communication protocols for a sensor transmitting plant state measurements over a wireless Markov fading channel to a receiver/controller. Communication requires power consumption at transmission adapted to channel fading, and at the receiver, which we model as constant at each transmission. We measure performance with a weighted sum of the average power consumption at both ends and an appropriately defined control task error. We derive an optimal self-triggered protocol where after each transmission devices decide when the next one will take place and switch to a zero-power sleep mode in between. We show that sleep durations need to adapt only to the current channel fading and not the plant state. We then derive an improved protocol allowing the sensor upon wake-up to decide whether to transmit or not based on current plant and channel conditions in an event-based fashion. The power/control performance improvements are illustrated in simulations.
Association of cholecystokinin‐A receptor gene polymorphisms and panic disorder in Japanese (2004)

Several lines of evidence have suggested that naturally occurring alterations in cholecystokinin (CCK) systems could contribute to the development of panic disorder (PD). Among recent investigations, polymorphisms of the CCK and CCK-B receptor (R) genes were investigated, but the results were inconclusive. We recently cloned the genomic structures of human CCK-AR, and determined the transcriptional start site of the human CCK-AR gene. Two sequence changes were detected in the promoter region: a G to T change in nucleotide -128 and an A to G change in nucleotide -81 (GenBank database under accession number D85606). The frequencies of the genotypes and haplotypes of these two polymorphisms were compared in 109 Japanese patients with PD and 400 age- and gender-matched normal Japanese control subjects. The frequency of variant genotypes (-81A/G, -128G/T; G/G, G/T, and G/G, T/T) having variant haplotype (-81G/-128T) was significantly higher in PD than in controls (P < 0.0001, OR = 2.81, 95% CI = 1.74-4.39). The statistical differences between the haplotype distributions in the PD and control groups were highly significant: the frequency of variant haplotype (-81G/-128T) was higher in the former group than in the latter (P < 0.0001). This association was not affected by clinical characteristics such as age, gender, and age at onset of PD. In this study, the first to report the positive association of the CCK-AR polymorphisms and PD, haplotype analyses further strengthened the association based on our comparison of genotype distributions. The CCK-AR gene polymorphism may be involved in the neurobiology of PD.
311 Development of Subsystem Modeling Method Using Statistical Energy Analysis : 2nd Report, Study on Defining Subsystem Network (2001)

This paper describes the technique of defining subsystem model in Experimental Statistical Energy Analysis (ESEA). SEA is applied to investigate the vibro-acoustic behavior of industrial structures like cars, trains, aircrafts and the others with high modal density and overlap in the middle and high frequency range. The structure is divided into subsystems complying with the SEA basic assumption: the structure must be divided in weakly coupled subsystems. In case of complex structure, many subsystems are defined and the large amount of measurement is required. This research proposes the effective method of subsystem modeling. The 2nd report shows the defining subsystem network for good prediction at the target subsystem. This technique can be improved to predict the noise and vibration of car body.
ChemInform Abstract: SYNTHESIS OF 2‐(4‐ISOBUTYLPIPERIDINO)PROPYL AMIDES OF EXPECTED ANTIINFLAMMATORY ACTION (1982)

Abstract Das aus 4‐Isobutyl‐piperidin mit 2‐Brom‐propionsäureethylester erhaltene Propionat (Ia) gibt nach Ammonolyse das Amid (Ib), das zum Amin (II) reduziert wird.
<![CDATA[<B>Obstruction of the systemic-pulmonary shunt in Fallot tetralogy</B>]]> (2005)

Obstrução de derivação sistêmico-pulmonar
Sexual Dimorphism in Lipid Metabolism and Gut Microbiota in Mice Fed a High-Fat Diet (2023)

The gut microbiome plays an essential role in regulating lipid metabolism. However, little is known about how gut microbiome modulates sex differences in lipid metabolism. The present study aims to determine whether gut microbiota modulates sexual dimorphism of lipid metabolism in mice fed a high-fat diet (HFD). Conventional and germ-free male and female mice were fed an HFD for four weeks, and lipid absorption, plasma lipid profiles, and apolipoprotein levels were then evaluated. The gut microbiota was analyzed by 16S rRNA gene sequencing. After 4-week HFD consumption, the females exhibited less body weight gain and body fat composition and significantly lower triglyceride levels in very-low-density lipoprotein (VLDL) and cholesterol levels in high-density lipoprotein (HDL) compared to male mice. The fecal microbiota analysis revealed that the male mice were associated with reduced gut microbial diversity. The female mice had considerably different microbiota composition compared to males, e.g., enriched growth of beneficial microbes (e.g., <i>Akkermansia</i>) and depleted growth of <i>Adlercreutzia</i> and <i>Enterococcus</i>. Correlation analyses suggested that the different compositions of the gut microbiota were associated with sexual dimorphism in body weight, fat mass, and lipid metabolism in mice fed an HFD. Our findings demonstrated significant sex differences in lipid metabolism and the microbiota composition at baseline (during LFD), along with sex-dependent responses to HFD. A comprehensive understanding of sexual dimorphism in lipid metabolism modulated by microbiota will help to develop more sex-specific effective treatment options for dyslipidemia and metabolic disorders in females.
Caching search engine results over incremental indices (2010)

A Web search engine must update its index periodically to incorporate changes to the Web. We argue in this paper that index updates fundamentally impact the design of search engine result caches, a performance-critical component of modern search engines. Index updates lead to the problem of cache invalidation: invalidating cached entries of queries whose results have changed. Naive approaches, such as flushing the entire cache upon every index update, lead to poor performance and in fact, render caching futile when the frequency of updates is high. Solving the invalidation problem efficiently corresponds to predicting accurately which queries will produce different results if re-evaluated, given the actual changes to the index.