gebhart/patrepeval huggingface dataset:
Design of a Closed-Loop Wireless Power Transfer System for an Implantable Drug Delivery Device (2023)

Active Implantable Medical Devices (AIMDs) have seen a significant increase in popularity in recent years due to their ability to provide continuous therapy unobtrusively. One of the key challenges in developing next generation AIMDs is the design of a safe and reliable Wireless Power Transfer (WPT) system. Standard commercial WPT components are not optimized to deliver small amounts of power or to work with other than small air gaps. We developed a near-field resonant inductive coupling WPT system with closed-loop real-time control, based on the commercial off-the-shelf components and leveraging the already integrated wireless communication system. The system was used to recharge a secondary battery and power supply the Nanochannel Delivery System (nDS). We tested the system’s robustness by varying the coil spacing to a maximum of 20mm, and by misaligning the coils laterally and angularly up to 8mm and 12°, respectively. We performed these tests by simulating battery charging from 2.8 V to 4.1 V and we tested four coils, from 6mm to 19mm in diameter, to evaluate the best trade-off between effectiveness and miniaturization. Finally, we recharged the selected battery for two distances, 2.5mm and 6.5mm. The results show that the 17mm and 19mm coils have the highest peak efficiencies of 31.3% and 32.3% (26% and 26.3% on average), respectively, and provide a complete and reliable battery recharge in less than 5 hours while keeping the receiver coil temperature within 2 °C.
Diabetic neuropathic pain: Physiopathology and treatment (2015)

Diabetic neuropathy is a common complication of both type 1 and type 2 diabetes, which affects over 90% of the diabetic patients. Although pain is one of the main symptoms of diabetic neuropathy, its pathophysiological mechanisms are not yet fully known. It is widely accepted that the toxic effects of hyperglycemia play an important role in the development of this complication, but several other hypotheses have been postulated. The management of diabetic neuropathic pain consists basically in excluding other causes of painful peripheral neuropathy, improving glycemic control as a prophylactic therapy and using medications to alleviate pain. First line drugs for pain relief include anticonvulsants, such as pregabalin and gabapentin and antidepressants, especially those that act to inhibit the reuptake of serotonin and noradrenaline. In addition, there is experimental and clinical evidence that opioids can be helpful in pain control, mainly if associated with first line drugs. Other agents, including for topical application, such as capsaicin cream and lidocaine patches, have also been proposed to be useful as adjuvants in the control of diabetic neuropathic pain, but the clinical evidence is insufficient to support their use. In conclusion, a better understanding of the mechanisms underlying diabetic neuropathic pain will contribute to the search of new therapies, but also to the improvement of the guidelines to optimize pain control with the drugs currently available.
Polyphenols in Wild and Weedy Mexican Common Beans (Phaseolus vulgarisL.) (2006)

The polyphenolic composition of 62 wild and weedy Mexican bean collections from diverse origins, grouped by their seed coat color, was assessed. According to spectrophotometric analysis, the range of total phenols, condensed tannins, and total anthocyanins presented wide differences. Furthermore, the phenolic acid, flavonoid, and anthocyanin profiles were analyzed using HPLC. Ferulic was the main phenolic acid. Kaempferol and quercetin were the main flavonoids, and the isoflavones daidzein and coumestrol were found in only low levels in few collections. Delphinidin was the main anthocyanidin found, followed by petunidin, cyanidin, malvidin, pelargonidin, and peonidin. The wide variation observed in polyphenolic contents was more related to their genotype than to the color factor. These results show that some wild and weedy beans are good sources of phenolic compounds for use in breeding programs focused on nutrition and health.
CT-ASSISTED VIRTUAL ENDOSCOPY: AN INNOVATIVE TOOL FOR DETECTING TISSUE PATHOLOGIES (2008)

You have accessJournal of Urology1 Apr 2008CT-ASSISTED VIRTUAL ENDOSCOPY: AN INNOVATIVE TOOL FOR DETECTING TISSUE PATHOLOGIES Hazem Orabi, Josh Tan, Tamer Aboushwareb, Anthony Atala, and James J Yoo Hazem OrabiHazem Orabi More articles by this author , Josh TanJosh Tan More articles by this author , Tamer AboushwarebTamer Aboushwareb More articles by this author , Anthony AtalaAnthony Atala More articles by this author , and James J YooJames J Yoo More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(08)61986-2AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "CT-ASSISTED VIRTUAL ENDOSCOPY: AN INNOVATIVE TOOL FOR DETECTING TISSUE PATHOLOGIES." The Journal of Urology, 179(4S), p. 679 © 2008 by American Urological AssociationFiguresReferencesRelatedDetails Volume 179Issue 4SApril 2008Page: 679 Advertisement Copyright & Permissions© 2008 by American Urological AssociationMetrics Author Information Hazem Orabi More articles by this author Josh Tan More articles by this author Tamer Aboushwareb More articles by this author Anthony Atala More articles by this author James J Yoo More articles by this author Expand All Advertisement PDF downloadLoading ...
Hypophosphatämie bei akuter respiratorischer Alkalose (2015)

Eine Hypophosphatamie ist eine potenziell bedrohliche Elektrolytstorung, die in unterschiedlichen klinischen Situationen auftreten kann.
Staphylococcus aureus CC30 Lineage and Absence of sed,j,r-Harboring Plasmid Predict Embolism in Infective Endocarditis (2018)

<i>Staphylococcus aureus</i> induces severe infective endocarditis (IE) where embolic complications are a major cause of death. Risk factors for embolism have been reported such as a younger age or larger IE vegetations, while methicillin resistance conferred by the <i>mecA</i> gene appeared as a protective factor. It is unclear, however, whether embolism is influenced by other <i>S. aureus</i> characteristics such as clonal complex (CC) or virulence pattern. We examined clinical and microbiological predictors of embolism in a prospective multicentric cohort of 98 French patients with monomicrobial <i>S. aureus</i> IE. The genomic contents of causative isolates were characterized using DNA array. To preserve statistical power, genotypic predictors were restricted to CC, secreted virulence factors and virulence regulators. Multivariate regularized logistic regression identified three independent predictors of embolism. Patients at higher risk were younger than the cohort median age of 62.5 y (adjusted odds ratio [OR] 0.14; 95% confidence interval [CI] 0.05-0.36). <i>S. aureus</i> characteristics predicting embolism were a CC30 genetic background (adjusted OR 9.734; 95% CI 1.53-192.8) and the absence of pIB485-like plasmid-borne enterotoxin-encoding genes <i>sed, sej</i>, and <i>ser</i> (<i>sedjr</i>; adjusted OR 0.07; 95% CI 0.004-0.457). CC30 <i>S. aureus</i> has been repeatedly reported to exhibit enhanced fitness in bloodstream infections, which might impact its ability to cause embolism. <i>sedjr</i>-encoded enterotoxins, whose superantigenic activity is unlikely to protect against embolism, possibly acted as a proxy to others genes of the pIB485-like plasmid found in genetically unrelated isolates from mostly embolism-free patients. <i>mecA</i> did not independently predict embolism but was strongly associated with <i>sedjr</i>. This <i>mecA</i>-<i>sedjr</i> association might have driven previous reports of a negative association of <i>mecA</i> and embolism. Collectively, our results suggest that the influence of <i>S. aureus</i> genotypic features on the risk of embolism may be stronger than previously suspected and independent of clinical risk factors.
State of the Art of Flow Management for Frac Plug Drillout and Flowback (2019)

Abstract Highly efficient multi-stage hydraulic fractured horizontal wellbores are the dominant completion method for many basins worldwide. One potential weakness of multi-stage hydraulic fracturing is that the later stages of the completion workflow – frac-plug drill out (FPDO) and flowback – cause large pressure fluctuations and transient flows through the perforation clusters that coincide with a period of low closure stress in the fractures. The proppant packs in the fractures during this period are fragile and prone to failure. Previously reported results show that flowback and initial production practices have a major impact on proppant production, maintenance and disposal costs and the subsequent well performance. In this paper the results from over 200 FPDO and flowback operations from the United States and Argentina are reviewed. These results show that maintaining a balanced flowrate during FPDO operations is critical for minimizing inadvertent damage to the hydraulic fracture network. The FPDO flowrate balance is the difference between the coiled tubing injection and annular return flowrates. The magnitude and sign of the balance corresponds to the instantaneous flowrate through the open perforation clusters into or out of the hydraulic fracture network. A positive balance rate, or overbalance, injects fluid into the fracture system. A negative balance rate, or underbalance, produces stimulation or formation fluids from the fracture network. Sudden changes between these two regimes creates local flows that can be severe enough to flush large quantities of proppant out of the fractures. Our results show that high-frequency multiphase flowmeters simplify the process of maintaining balance (no inflow, no outflow). Furthermore, close monitoring of any imbalance that develops, and rapid control of the surface choke and injection rate, can provide for an efficient operation while protecting the integrity of the fracture system. Early monitoring of flowback and production with a high frequency flowmeter was shown to be extremely useful technique for optimizing well productivity during well clean-up. This paper also shows how a dual energy gamma ray multiphase flowmeter successfully quantified proppant produced during FPDO and flowback. Examples of the dynamics of sand production are shown, as well as correlations to events of excessive underbalance conditions. At the end of the paper we show that most of the highlighted problems can be solved through making changes to the well construction workflow and accounting for relationships between various well operations. Incorporation of this workflow enables early prediction of well performance issues and their efficient resolution.
Heat of Absorption and Specific Heat of Carbon Dioxide in Aqueous Solutions of Monoethanolamine,3-piperidinemethanol and Their Blends (2014)

In this work the thermodynamic properties of monoethanlonamine (MEA), 3-piperidinemethanol (3PM) and their blends were measured and evaluated. The heat of absorption of the solution of CO2 in the aqueous solution of single amines (5 M MEA,3 M MEA, 2 M MEA, 2 M 3PM and 3 M 3PM) and aqueous amine blends (2 M MEA+ 3 M 3PM, 3 M MEA + 2 M 3PM, 3 M MEA + 3 M 3PM) were measured isothermally using a commercially available micro-reaction calorimeter (μRC) at three different temperatures (313.15, 333.15 and 353.15) K and at different CO2 loading capacity. The vapour liquid equilibrium apparatus was also used to obtain different samples of loaded CO2 molCO2/molamine and their corresponding heat of absorption was measured using the micro-reaction calorimeter. In addition, the heat capacities of the above amines were also measured from 303.15 K to 353.15 K at an interval of 5 K. The calorimetric measurements of the heat of absorption at temperature (313.15 oK) indicated that the (3 M MEA + 2 M 3PM) blend has the lowest absorption enthalpy with 75.58 kJ/mol CO2 at 0.56 molCO2/molamine (max loading capacity) than (5M-MEA) with a reported value of 87.827 kJ/molCO2 at 0.51 molCO2/molamine which corresponds the maximum loading capacity of (5M-MEA). The (3 M MEA + 3 M 3PM) exhibited the lowest heat capacities among the measured blends of MEA and 3PM. 5 M MEA was used as a base case for all the experimental measurements for the heat of absorption.
Biomechanical Impact of Localized Corneal Cross-linking Beyond the Irradiated Treatment Area (2019)

The stiffening effect of L-CXL extends beyond that of the irradiated area. When considering L-CXL protocols clinically, it will be important to account for increased stiffening in surrounding regions. [J Refract Surg. 2019;35(4):253-260.].
Web Application Safety by Vulnerability Assessment and Penetration Testing using SQL Injection Techniques (2020)

Today's world is largely dependent on the internet; global internet users are growing more rapidly. People are more developing their skills and getting advanced in every field using internet. In the same time SECURITY has become the major issue of the internet. Sharing data from the wireless technology can be easily breach the security by hackers and access their confidential data. Vulnerability Assessment and penetration testing is a solution for problem to overcome. A Vulnerability Assessment is the process of defining, identifying the vulnerabilities. A Penetration Testing, is a process to attack in a computer system or network with an authority to evaluate and analyze the computer and network security. The purpose of this testing method is to fix the loopholes and secure the data from the skilled hackers. In our project we are going to show one of the web hacking technique i.e. SQL injection.
Paraffinic metal–organic polyhedrons: solution-processable porous modules exhibiting three-dimensional molecular order (2018)

Metal-organic polyhedral cages substituted with paraffinic side chains were designed as solution-processable porous modules, which provide soft materials possessing self-organized cavity structures with three-dimensional molecular order in a lyotropic mesophase. The macroscopic shape of the resulting soft materials can be easily modified through solution-based processes.
SAViR-T: Spatially Attentive Visual Reasoning with Transformers (2022)

We present a novel computational model, "SAViR-T", for the family of visual reasoning problems embodied in the Raven's Progressive Matrices (RPM). Our model considers explicit spatial semantics of visual elements within each image in the puzzle, encoded as spatio-visual tokens, and learns the intra-image as well as the inter-image token dependencies, highly relevant for the visual reasoning task. Token-wise relationship, modeled through a transformer-based SAViR-T architecture, extract group (row or column) driven representations by leveraging the group-rule coherence and use this as the inductive bias to extract the underlying rule representations in the top two row (or column) per token in the RPM. We use this relation representations to locate the correct choice image that completes the last row or column for the RPM. Extensive experiments across both synthetic RPM benchmarks, including RAVEN, I-RAVEN, RAVEN-FAIR, and PGM, and the natural image-based "V-PROM" demonstrate that SAViR-T sets a new state-of-the-art for visual reasoning, exceeding prior models' performance by a considerable margin.
<title>Transfer matrix formalism for the stationary response of nonlinear, multilayered structures for optical bistability</title> (1990)

The transfer matrix formalism, well known to describe the linear optical response of multilayered structures, is extended to the plane wave response of multilayered structures with an arbitrary number of Ken-type nonlinear layers, and including linear absorption too. It is shown that the dummy variable technique, well known in the description of the nonlinear Fabry-Perot, can be extended for multilayered structures. Several effects are highlighted for both superlattices and nonlinear interference filters.
The Influence of Time of Day of Vaccination with BNT162b2 on the Adverse Drug Reactions and Efficacy of Humoral Response against SARS-CoV-2 in an Observational Study of Young Adults (2022)

An increasing body of evidence from both academic and clinical studies shows that time-of-day exposure to antigens might significantly alter and modulate the development of adaptive immune responses. Considering the immense impact of the COVID-19 pandemic on global health and the diminished efficacy of vaccination in selected populations, such as older and immunocompromised patients, it is critical to search for the most optimal conditions for mounting immune responses against SARS-CoV-2. Hence, we conducted an observational study on 435 healthy young adults vaccinated with two doses of BNT162b2 (Pfizer-BioNTech) vaccine to determine whether time-of-day of vaccination influences either the magnitude of humoral response or number of adverse drug reactions (ADR) being reported. We found no significant differences between morning and afternoon vaccination in terms of both titers of anti-Spike antibodies and frequency of ADR in the studied population. In addition, our analysis of data on the occurrence of ADR in 1324 subjects demonstrated that the second administration of vaccine in those with previous SARS-CoV-2 infection was associated with lower incidence of ADR. In aggregate, vaccination against COVID-19 with two doses of BNT162b2 mRNA vaccine is presumed to generate an equally efficient anti-Spike humoral response.
Controlling Atomic Layer Deposition of TiO2 in Aerogels through Surface Functionalization (2009)

This report demonstrates a chemical functionalization method for controlling TiO2 ALD in low-density nanoporous materials, i.e., aerogels. Functionalization of silica aerogel with trimethylsilane is shown to inhibit TiO2 growth on the aerogel via ALD. A proposed mechanism for the deactivation effect is the blocking of surface functional groups, such as hydroxyl (OH) moieties, which serve as chemisorption sites for the ALD precursors and hence are essential for nucleating the deposition process. Subsequent modification of the aerogel functionalization through the selective removal of hydrocarbon groups via heat or plasma treatment reactivates the aerogel towards deposition, thereby resulting in TiO2 growth. The results presented here demonstrate the use of ALD as a selective tool for creating novel nanoporous materials.
Green Recyclable CuO‐CeO2 Nanocomposite Catalyzed Amination of Aryl Halides with Aqueous Ammonia in Water (2014)

Abstract CuO‐CeO 2 nanocomposite as a green recyclable catalyst, catalyzed amination of aryl halides with aqueous ammonia in water. This catalyst can be easily recovered by simple filtration and recycled up to 5 consecutive runs with consistent activity. The procedure provides some advantages such as simple work‐up, clean procedure, relatively short reaction times and high yields of the products.
Improvement of energy confinement time by continuous pellet fuelling in beam-heated Doublet III limiter discharges (1985)

A centrifuge injector that repetitively fires 1.3 mm deuterium pellets (1 torr⋅L per pellet) at a rate of 32 pellets per second was used to build up and maintain a Doublet III 2.4 MW neutral-beam-heated limiter discharge at a line-averaged density of 1 × 1014 cm−3. When compared to a conventional gas-fuelled plasma at similar density, the pellet-fuelled plasma was characterized by a factor-of-three reduction in edge neutral density and limiter recycling, a centrally peaked profile, a 70% increase in global energy confinement, and a tenfold increase in the fusion reaction rate.
Molecular physiology of higher plant sucrose transporters (2007)

Sucrose is the primary product of photosynthetic CO(2) fixation that is used for the distribution of assimilated carbon within higher plants. Its partitioning from the site of synthesis to different sites of storage, conversion into other storage compounds or metabolic degradation involves various steps of cell-to-cell movement and transport. Many of these steps occur within symplastic domains, i.e. sucrose moves passively cell-to-cell through plasmodesmata. Some essential steps, however, occur between symplastically isolated cells or tissues. In these cases, sucrose is transiently released into the apoplast and its cell-to-cell transport depends on the activity of plasma membrane-localized, energy dependent, H(+)-symporting carrier proteins. This paper reviews the current knowledge of sucrose transporter physiology and molecular biology.
Community Sediment Transport Modeling, National Ocean Partnership Program (2009)

Abstract : The goal of the Community Sediment Transport Modeling System (CSTMS) was to produce an open-source model that couples hydrodynamics (circulation and waves), sediment transport, and morphodynamics. The model is intended to be used as both a research tool and for practical applications. An accurate and useful model requires coupling sediment-transport with hydrodynamic forcing and stratigraphic evolution. Ultimately, the modeling system will consist of interoperable modules, conforming to a community-accepted standard such as the Earth System Modeling Framework (ESMF).
Síntesis y preparación de nuevos macrociclos pseudopeptídicos quirales. Aplicaciones en química supramolecular (2008)

En esta tesis se aborda la preparacion y estudio de las propiedades supramoleculares de macrociclos pseudopeptidicos de tamano grande (mas de 30 eslabones). El contenido de la misma se ha dividido del siguiente modo: - En los capitulos 1 y 2 se aborda la problematica en la sintesis de este tipo de compuestos y se plantean dos estrategias diferentes para mejorar la reaccion de macrociclacion. - En el capitulo 3 se estudia la aplicacion de los macrociclos sintetizados como receptores de dipeptidos. - En el capitulo 4 se estudian las propiedades de autoasociacion de estos macrociclos pseudopeptidicos para dar lugar a sistemas nanoestructurados.
Optical amplification and its use in communications (1990)

Current trends in both long haul transmission and optical networks indicate no slowing down in the move towards increased capacity and network complexity. These requirements have highlighted the limitations of the digital techniques that are the backbone of the current technology. Optical amplifiers offer potential solutions to many of these. This paper reviews the operation of these amplifiers, the current state of their development, and the future prospects for deployment.
Dependence of the Anchoring Energy on the Applied Voltage in a Nematic Cell (2006)

A nematic liquid crystal cell in the shape of a slab of thickness d and containing ionic impurities is considered in the presence of a dc voltage. A complete theoretical model to determine the electric field distribution across the sample is used to explain the experimental dependence of the effective anchoring energy of the cell on the applied voltage, in the limit of high voltage.