gebhart/patrepeval huggingface dataset:
A 12-Bit 75-MS/s Pipelined ADC Using Incomplete Settling (2007)

The residue amplifiers in high-speed pipelined analog-to-digital converters (ADCs) typically determine the converter's overall speed and power performance. We propose a mixed-signal technique that exploits incomplete settling to achieve low power residue amplification. In the first stage of a 12-bit, 75-MS/s proof-of-concept prototype, the employed open-loop residue amplifier dissipates only 2.9 mW from a 3-V supply, achieving >60% amplifier power reduction over a previously reported open-loop residue amplifier implementation and achieving >90% amplifier power reduction over a conventional opamp implementation. Test results show that the converter's maximum signal-to-noise-and-distortion ratio (SNDR) is 65.6 dB. The measured integral and differential nonlinearity are 0.95 LSB and 0.64 LSB, respectively. The experimental chip occupies 7.9 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> and consumes 273 mW in a 0.35-mum double-poly, quadruple-metal CMOS process
The current state of the science related to the re-release of mercury from coal combustion products (2006)

The stability of mercury associated with CCPs is an issue that has only recently been under investigation but has become a prominent question as the industry strives to determine if current management options for CCPs will need to be modified. Mercury and other air toxic elements can be present in fly ash, FGD material and bottom ash and boiler slag. Mercury concentrations ranging from {lt} 0.01 to 2.41 ppm in fly ash and from 0.001 to 0.342 ppm in bottom ash have been reported. Stability of mercury must be evaluated by tests that include 1) direct leachability; 2) vapor-phase release at ambient and elevated temperatures; and 3) microbiologically induced leachability and vapor-phase release. The amount of mercury leached from currently produced CCPs is extremely low and does not appear to represent an environmental or re-release hazard. Concentrations of mercury in leachates from fly ashes and FGD material using either the toxicity characteristic leaching procedure (TCLP) or the synthetic groundwater leaching procedure (SGLP) are generally below detection limits. The release of mercury vapor from CCPs resulting from the use of mercury control technologies has been evaluated on a limited basis. Research indicates that mercury bound to the ash or activated carbonmore » is fairly stable. The EERC found that organomercury species were detected at very low levels both in the vapor and leachate generated from the microbiologically mediated release experiments. The current state of the science indicates that mercury associated with CCPs is stable and highly unlikely to be released under most management conditions, including utilisation and disposal. The exception to this is exposure to high temperatures such as those that may be achieved in cement and wallboard production. Therefore, existing CCPs management options are expected to be environmentally sound options for CCPs from systems with mercury control technologies installed. 2 refs., 2 photos.« less
PROPERTIES OF VARIOUS ANTI-γ-GLOBULIN FACTORS IN HUMAN SERA (1965)

The serological and physicochemical properties of the following three forms of human anti-gamma-globulin factors were compared: (a) rheumatoid factors; (b) Milgrom type anti-gamma-globulin factors; and (c) factors directed against an antigen in human gammaG-globulin that is hidden in the intact molecule and revealed by enzymatic digestion at low pH. The property common to these factors is ability to interact with human gammaG-globulin; they are distinguishable because they react with different antigenic groups on this molecule. In all of five sera, the Milgrom type anti-gamma-globulin factors were gammaM-globulins. They reacted with various human gammaG-globulin antibodies but failed to interact with gammaM-globulin type antibodies in agglutination and absorption experiments. When isolated from other anti-gamma-globulin factors, they agglutinated red cells coated with intact anti-Rh antibodies, but failed to react with cells cells coated with pepsin-digested anti-Rh antibody. These observations indicate that the agglutinator reacts with the crystallizable, inert fragment of gammaG-globulin. Anti-gamma-globulin activity directed against an antigen in human gammaG-globulin revealed by pepsin digestion was demonstrated in gammaG-, gammaA-, and gammaM-globulins. This anti-gamma-globulin factor could be absorbed by antigen-antibody precipitates containing human antibody, which shows that the hidden antigen in human gammaG-globulin is revealed not only by enzymatic digestion at low pH, but also when gammaG-globulin is present as antibody in an antigen-antibody precipitate. Rheumatoid factors and Milgrom type anti-gamma-globulin factors were also absorbed by antigen-antibody precipitates containing human antibody. The results indicate that the three distinct forms of antigamma-globulin factors may all be produced as a result of antigenic stimulation by autologous antigen-antibody complexes.
Company on the Couch (2008)

In positioning the “Company on the Couch,” management consultants have increasingly called attention to toxic behavior in dysfunctional organizations. This article addresses how the mismanagement and failure to accurately and timely identify people problems in organizations is in itself a form of toxic leadership. Via two consultations presented in the form of case studies, this article illustrates how complex webs of organizational dysfunction are frequently an outgrowth of mild, unchecked toxicity in the workplace. Recommendations and initiatives are provided to better prepare managers for timely and accurate toxin detection and handling.
A Bipartite Activation Domain Is Responsible for the Activity of Transcription Factor HNF1/LFB1 in Cells of Hepatic and Nonhepatic Origin (1993)

HNF1/LFB1 is a transcription factor that controls the expression of several liver-specific genes. Previous in vitro experiments allowed us to identify two different regions in the carboxy-terminal portion of the protein responsible for most of the transcription activation potential: the first, ADI, between amino acids 546 and 628 and the second, ADII, between amino acids 281 and 318. To characterize the molecular anatomy of HNF1/LFB1 better, we have analyzed its trans-activating properties in vivo. Several HNF1/LFB1 deletion mutants were tested for their ability to induce transcription from HNF1/LFB1-dependent synthetic promoters in cells of hepatic and nonhepatic origin. These last recipient cells provide an HNF1/LFB1-deficient environment that is useful for a precise quantification of the recombinant protein. Our results confirm the importance of ADI and indicate that no activating property can be assigned to ADII in vivo. Moreover, a novel glutamine/proline-rich activation domain (ADIII) has been identified between amino acids 440 and 506. These findings are confirmed by domain-swapping experiments, carried out with the heterologous GAL4 DNA-binding domain, which also show that the activity of each individual activation domain is influenced by combining adjacent HNF1/LFB1 sequences. The data presented indicate that HNF1/LFB1 transcription activating potential relies on a complex structure and also provide important clues to understanding the different functions exerted by transcription factors of this family.
<title>Industrial lasers in Japan</title> (1991)

I am to report on some aspects of industrial lasers in Japan. Mostly centering on the market. In Japan, the history of laser developnent is rather profound. And long. Ever since the first invention of the laser in this country in 1960. This is partly because of the fact that in Japan the spectroscopic studies of the ruby was very popular in the late 1950's. Ever since niost of the work has been done in the research laboratories of the industry, not in the universities or not in the governmental laboratories. And since that time our first activity was mainly centering on the basic research, but after that time we have the evolution of the technology. One of the features in Japan is that the activity of developement and research of laser technology from the very basic phase up to the present commercialization has been done by the same group of people, including ine. We had a national project which ended about six years ago which was sponsored by MITI. MITI is Ministry of International Trade and Industry in Japan. And because of this national project, the effect of this project had a very enlightening effect in Japan. And after that our Japanese laser market became very flourishing.
Polysomnographic sleep recording with simultaneously acquired 12 lead ECGs: a study for detection and validation of apnea related ECG changes (2003)

The aim of our study was to investigate whether morphological ECG parameters are changed during sleep disorders, in particular during apnea. We have set up jointly with the sleep laboratory of Marburg University a new database with polysomnographic and simultaneously recorded 12 lead ECG data. Analyses results on single cases and on a data set of 9 patients are presented. They confirm our hypothesis that morphologic ECG parameters vary systematically with apnea phases. While mean values differences seem to be small between regular and apnea respiration, standard deviations of these parameters are marked. From a separate analysis of data for each type of apnea and a joint processing of heart rate variability we expect additional insight into the reasons for the morphologic ECG changes.
Applicability of a recycle reactor scheme to the conversion of methane to aromatics (2003)

We have proved in this study that a two-bed recycle reactor scheme can overcome the yield barrier for oxidative coupling of methane (OCM) by converting the C2 products to aromatics. Such a design places new demands on the catalysts, however, since the OCM catalyst must operate in the presence of aromatics, and the aromatization catalyst must tolerate the unreacted methane. This work focuses on the design of such catalyst materials and improvement of the system performance through adjusting the operating parameters. The catalysts were prepared by incipient wetness impregnation. Experimental studies were conducted in a quartz fixed bed flow reactor at atmospheric pressure, and the analysis was carried out by an online gas chromatograph (Agilent 6890). The set of operating conditions that demonstrated product yield improvement in the recycle configuration are 800°C, 0.002gmin/ml and a 10wt%LiCl/15wt%MnO2/SiO2 catalyst loading for the OCM and 550°C, 0.04gmin/ml and a loading of 1wt%Pt-5wt%Ga/ZSM-5 for the aromatization reactions. We showed that our system produces 40% aromatics, mainly benzene and a small amount of toluene (B/T product ratio is 20/1), at a recycle ratio of 11 under relatively high methane/oxygen feed flow conditions. Although there is still room for improvement of several issues, one being implementing a means of catalyst regeneration, our system brings both capital and operating cost advantages since it is a simple two-reactor recycle configuration with no intermediate separations. The aromatics yield we obtained from our scheme is double the value that can be obtained from the operation of the best available OCM and aromatization reactors in series. Finally, we have also developed in this research a strategy for experimental analysis of the patterned reactors viability that can be applied to other types of reactions networks.
SARI: Shared Autonomy across Repeated Interaction (2022)

Assistive robot arms try to help their users perform everyday tasks. One way robots can provide this assistance is shared autonomy. Within shared autonomy, both the human and robot maintain control over the robot's motion: as the robot becomes confident it understands what the human wants, it intervenes to automate the task. But how does the robot know these tasks in the first place? State-of-the-art approaches to shared autonomy often rely on prior knowledge. For instance, the robot may need to know the human's potential goals beforehand. During long-term interaction these methods will inevitably break down -- sooner or later the human will attempt to perform a task that the robot does not expect. Accordingly, in this paper we formulate an alternate approach to shared autonomy that learns assistance from scratch. Our insight is that operators repeat important tasks on a daily basis (e.g., opening the fridge, making coffee). Instead of relying on prior knowledge, we therefore take advantage of these repeated interactions to learn assistive policies. We introduce SARI, an algorithm that recognizes the human's task, replicates similar demonstrations, and returns control when unsure. We then combine learning with control to demonstrate that the error of our approach is uniformly ultimately bounded. We perform simulations to support this error bound, compare our approach to imitation learning baselines, and explore its capacity to assist for an increasing number of tasks. Finally, we conduct three user studies with industry-standard methods and shared autonomy baselines, including a pilot test with a disabled user. Our results indicate that learning shared autonomy across repeated interactions matches existing approaches for known tasks and outperforms baselines on new tasks. See videos of our user studies here: https://youtu.be/3vE4omSvLvc
Regulatory Effects of Novel Neurotrophin-1/B Cell-Stimulating Factor-3 (Cardiotrophin-Like Cytokine) on B Cell Function (2002)

We describe regulatory effects that a novel neurotrophin-1/B cell-stimulating factor-3 (NNT-1/BSF-3; also reported as cardiotrophin-like cytokine) has on B cell function. NNT-1/BSF-3 stimulates B cell proliferation and Ig production in vitro. NNT-1/BSF-3-transgenic mice, engineered to express NNT-1/BSF-3 in the liver under control of the apolipoprotein E promoter, show B cell hyperplasia with particular expansion of the mature follicular B cell subset in the spleen and the prominent presence of plasma cells. NNT-1/BSF-3-transgenic mice show high serum levels of IgM, IgE, IgG2b, IgG3, anti-dsDNA Abs, and serum amyloid A. NNT-1/BSF-3-transgenic mice also show non-amyloid mesangial deposits that contain IgM, IgG, and C3 and are characterized by a distinctive ultrastructure similar to that of immunotactoid glomerulopathy. NNT-1/BSF-3-transgenic mice produce high amounts of Ag-specific IgM, IgA, and IgE and low amounts of IgG2a and IgG3. Normal mice treated with NNT-1/BSF-3 also produce high amounts of Ag-specific IgE. NNT-1/BSF-3 regulates immunity by stimulating B cell function and Ab production, with preference for Th2 over Th1 Ig types.
Synthesis, Biological Evaluation, and Quantitative Structure−Activity Relationship Analysis of New Schiff Bases of Hydroxysemicarbazide as Potential Antitumor Agents (2001)

Thirty Schiff bases of hydroxysemicarbazide (Ar-CH=NNHCONHOH) have been synthesized and tested against L1210 murine leukemia cells. The IC(50) values were found to be in a range from 2.7 x 10(-6) to 9.4 x 10(-4) M. A total of 17 out of the 30 compounds had higher inhibitory activities than hydroxyurea (an anticancer drug currently used for the treatment of melanoma, leukemia, and ovarian cancer) against L1210 cells. Six compounds with IC(50) values in micromolar range were 11- to 30-fold more potent than hydroxyurea (IC(50) = 8.2 x 10(-5) M). The partition coefficient (log P) and ionization constants (pK(a)) of a model compound [1-(3-trifluoromethylbenzylidene)-4-hydroxysemicarbazide, 1] were measured by the shake-flask method, and the measured log P was used to derive Hansch-Fujita pi constant of -CH=NNHCONHOH. On the basis of the newly derived pi and those of other moieties, the partition coefficients (SlogP) of the other 29 compounds were calculated by the summation of pi values. Quantitative structure-activity relationship (QSAR) analysis showed that, besides the essential pharmacophore (-NHCONHOH), hydrophobicity (SlogP), molecular size/polarizability (calculated molar refractivity), and the presence of an oxygen-containing group at the ortho position (I) were important determinants for the antitumor activities. In conclusion, the results obtained in this study show that several Schiff bases of hydroxysemicarbazide are potent inhibitors of tumor cells and warrant further investigation as cancer chemotherapeutic agents.
Trait Theory and Cross-Cultural Studies of Person Perception (1994)

(1994). Trait Theory and Cross-Cultural Studies of Person Perception. Psychological Inquiry: Vol. 5, No. 2, pp. 114-117.
Fabrication and Characterization of Porous Alumina Tube with Pore Gradient (2005)

The porous alumina tube with pore gradient along the radial direction was successfully fabricated, where PMMA particles were used as pore former agent. The specimen was expected as a filter subjected to high temperatures. Alumina and PMMA particle were mixed with water to form aqueous slurry, compacted using centrifugal molding technique. The green body was dried in partial vacuum atmosphere, calcinated at 273 K to remove the organic component, sintered at 1623 K to obtain sintered porous a-alumina tubes. The control on the pore gradient of porous tubes was attempted by two ways; lamination and continuous methods. The microstructure observation showed that the inner part of the tubes had higher porosity than the outer part irrespective of the method used. Porous alumina tubes were characterized by microstructure observation, porosity and air permeability. The binary pores of 10µm and submicron in diameter were visible, which were formed by the burning-out PMMA particles and lower sintering temperature, respectively. The influence of PMMA amount on the pore morphology of the tubes was investigated. Fracture strength was carried out by the O-ring diametral compression testing. An analytical formula subject to the diametral testing was introduced with considering the porosity gradient. The correlations between the fracture strength and pore gradient were investigated, where a reduction in fracture strength was observed with the increase in laminated layers, and minimum strength was found in continuous porous tubes.
Characterization of SiGe thin films using a laboratory X-ray instrument (2013)

The technique of reciprocal space mapping using X-rays is a recognized tool for the nondestructive characterization of epitaxial films. X-ray scattering from epitaxial Si<sub>0.4</sub>Ge<sub>0.6</sub> films on Si(100) substrates using a laboratory X-ray source was investigated. It is shown that a laboratory source with a rotating anode makes it possible to investigate the material parameters of the super-thin 2-6 nm layers. For another set of partially relaxed layers, 50-200 nm thick, it is shown that from a high-resolution reciprocal space map, conditioned from diffuse scattering on dislocations, it is possible to determine quantitatively from the shape of a diffraction peak (possessing no thickness fringes) additional parameters such as misfit dislocation density and layer thickness as well as concentration and relaxation.
Modulated electrohyperthermia as part of immunogenic cell death treatment in pediatric neuro-oncology (2019)

Introduction The induction of immunogenic cell death (ICD) becomes an important treatment methodology in cancer. Convincing data demonstrate that modulated electrohyperthermia (mEHT) contribute to ICD. No data have been reported about the use of mEHT in a large pediatric brain cancer population. METHODS. We retrospectively analyzed a series of 76 children treated at IOZK with multimodal immunotherapy consisting of the combination of Newcastle Disease Virus (NDV) injections with mEHT and autologous dendritic cell vaccines IO-VAC. RESULTS. There were 46 females and 30 males with a median age of 6.5 resp. 9.5 years (range 1 – 19y resp. 2 – 18y). Diagnoses were anaplastic astrocytoma (6), Brain stem glioma (1), chordoma (1), DIPG (45), Ependymoma (4), GBM (12), medulloblastoma (3), pilocytic astrocytoma (1), pineoblastoma (1), choroid plexus carcinoma (1), unspecified (1). In total 811 mEHT sessions were given. Median number of mEHT sessions per child were 15, ranging up to 53. In all cases, mEHT doses were 40 Watt during 40 minutes. Treatments were feasible without sedation. There were no intervention-related side effects. NDV injections were associated to the mEHT sessions. Multimodal immunotherapy included the DC vaccinations with IO-VAC. In total 77 IO-VAC vaccines were produced, and in median 2 (range 0 – 4) IO-VAC vaccines were given per child. The use of PanTum Detect tests seemed reliable to monitor on daily basis the response to ICD treatment and over the treatment course. Median overall survival of 28 DIPG children treated with multimodal immunotherapy as part of their primary treatment showed a median overall survival of 14 months. Remarkable long-term remissions were also observed in a child with relapsed pineoblastoma and a child with metastasized Myc-amplified medulloblastoma group 3. CONCLUSION. Modulated electrohyperthermia for children with brain cancer as part of multimodal immunotherapy is feasible and safe. Response to treatment could be monitored. Multimodal immunotherapy contributed to improved tumor control and overall survival.
Structured Catalysts for Environmental and Energetical Applications (2006)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
LEDAkem: a post-quantum key encapsulation mechanism based on QC-LDPC\n codes (2018)

This work presents a new code-based key encapsulation mechanism (KEM) called\nLEDAkem. It is built on the Niederreiter cryptosystem and relies on\nquasi-cyclic low-density parity-check codes as secret codes, providing high\ndecoding speeds and compact keypairs. LEDAkem uses ephemeral keys to foil known\nstatistical attacks, and takes advantage of a new decoding algorithm that\nprovides faster decoding than the classical bit-flipping decoder commonly\nadopted in this kind of systems. The main attacks against LEDAkem are\ninvestigated, taking into account quantum speedups. Some instances of LEDAkem\nare designed to achieve different security levels against classical and quantum\ncomputers. Some performance figures obtained through an efficient C99\nimplementation of LEDAkem are provided.\n