gebhart/patrepeval huggingface dataset:
PSV-22 Effects of different fat sources and vitamin E levels/isoforms on growth performance, antioxidant status, and fatty acid profile in the liver of pigs grown to 150 kg (2019)

Abstract The study objective was to assess the contribution of fat source and vitamin E (VE) supplementation on growth performance, antioxidant status, and fatty acid profile in the liver of pigs at heavy slaughter weight (148.09 ±1.64 kg). A total of 72 individually-fed pigs (36 barrows, 36 gilts; 28.55 ±1.16 kg) were randomly assigned to 12 dietary treatments in a 2 × 6 factorial arrangement. Fat treatments were tallow and corn-oil. The VE treatments included four levels of α-tocopheryl-acetate (ATA; 11, 40, 100, and 200 ppm) and two levels of mixed tocopherols (primarily γ-tocopherol; 40 and 100 ppm). Liver samples were collected at slaughter. Data analysis were performed by ANOVA using GLM in SAS. No effect of dietary fat sources, isoforms of VE, and levels of γ-tocopherol were detected on growth performance or liver antioxidant status (GSH, GSSG, SOD, and MDA). Increasing dietary ATA linearly increased overall ADG (0.98, 1.02, 1.02, and 1.08 kg/day; P = 0.02) from 28 to 150 kg; overall ADG of pigs fed γ-tocopherol-diets was 1.07 and 1.04 kg/day, respectively. An interaction between fat sources and ATA was observed on cumulative ADG during Phase1-3 (28-100 kg; P = 0.04) and Phase1-4 (28-125 kg; P = 0.03) wherein pigs fed corn-oil-diet, but not tallow-diet, had increased ADG with increased dietary ATA. Increasing dietary ATA quadratically increased SOD activity (P &lt; 0.05; highest at 100 ppm), and quadratically decreased MDA content (P &lt; 0.05; lowest at 40 ppm) in the liver. Liver fatty acid profile was affected by fat source (P &lt; 0.05) but not VE treatment, pigs fed corn-oil-diets had less SFA (34.23 vs. 35.45%; P = 0.02) and MUFA (11.98 vs. 18.38%; P &lt; 0.0001), but more PUFA (49.14 vs. 40.78%; P &lt; 0.0001) than pigs fed tallow-diets in the liver. Beneficial effects of dietary VE supplementation were observed on growth performance and antioxidant status of pigs under conditions of this study.
SemEval-2016 Task 5: Aspect Based Sentiment Analysis (2016)

Maria Pontiki, Dimitris Galanis, Haris Papageorgiou, Ion Androutsopoulos, Suresh Manandhar, Mohammad AL-Smadi, Mahmoud Al-Ayyoub, Yanyan Zhao, Bing Qin, Orphée De Clercq, Véronique Hoste, Marianna Apidianaki, Xavier Tannier, Natalia Loukachevitch, Evgeniy Kotelnikov, Nuria Bel, Salud María Jiménez-Zafra, Gülşen Eryiğit. Proceedings of the 10th International Workshop on Semantic Evaluation (SemEval-2016). 2016.
A computational model of afferent neural activity from the cochlea to the dorsal acoustic stria (1991)

The first comprehensive computational model of the precortical mammalian auditory system to include afferent neural processing up to the level of the dorsal acoustic stria (DAS) is described. The model consists of two scissile stages simulating (1) the cochlea and auditory nerve (AN) and (2) the dorsal cochlear nucleus (DCN). The model derives its input from a 128-channel cochlear filterbank. Cochlear transduction, rectification, logarithmic compression, and two-tone suppression functions are performed at the first stage of the simulation. The 512 artificial neurons employed model the cell at the level of transmembrane potential and have interconnections that follow closely those reported in recent anatomical and physiological studies of the cat AN and DCN. The responses of the model to pure-tone stimuli (at various sound-pressure levels) and noise stimuli (at various levels and bandwidths) are reported in detail and compare well with published results. The model is being used to investigate the representation of initial English stop consonants (differing in voice-onset time) in the DAS; this work is briefly described.
Dioxiranes: a new class of powerful oxidants (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDioxiranes: a new class of powerful oxidantsWaldemar Adam, Ruggero Curci, and John O. EdwardsCite this: Acc. Chem. Res. 1989, 22, 6, 205–211Publication Date (Print):June 1, 1989Publication History Published online1 May 2002Published inissue 1 June 1989https://pubs.acs.org/doi/10.1021/ar00162a002https://doi.org/10.1021/ar00162a002research-articleACS PublicationsRequest reuse permissionsArticle Views2072Altmetric-Citations565LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Evaluation of cardiovascular risk factors in HIV-1 infected patients using carotid intima-media thickness measurement (2002)

It was concluded that only conventional cardiovascular risk factors are independently associated with increased IMT in HIV-infected patients.
Shoot Regeneration and Bulblet Formation from Shoot and Root Meristem of Garlic Cv Bangladesh Local (2002)

1 Abstract: Tissue culture is considered as an alternative tool for garlic breeding as traditional breeding is not possible due to its sterility. A study was carried out to develop a protocol of regeneration in Bangladesh local garlic. Shoot and root meristems of garlic cv. Bangladesh local were cultured on Murashige and Skoog (MS) medium containing various growth regulator combinations. Regeneration from shoot meristem was found with all medium composition but highest (95.55%) in growth regulator-free medium. Shoots were transferred onto media containing BA or high level of sucrose. Forty per cent (40.00%) of the root meristem regenerated shoots on MS medium supplemented with 1 µM NAA and 10 µM BA. The shoots were multiplied on MS medium containing 0.5 µM BA. Bulblets were obtained from the regenerated shoots of garlic in all the media. It is the first to report regeneration from any Bangladeshi garlic.
Nopp140 Is a Mediator of the Protein Kinase A Signaling Pathway That Activates the Acute Phase Response α1-Acid Glycoprotein Gene (2002)

The acute phase response (APR) in liver during inflammation is one of the well known examples for elucidating the signaling pathways that lead to the combinatorial regulation of gene expression. The APR is exemplified by alpha(1)-acid glycoprotein gene (agp) expression. A number of transcription factors, including CCAAT/enhancer-binding protein beta (C/EBPbeta), glucocorticoid receptor, cAMP-response element-binding protein (CREB), and Nopp140, are known to participate in its induction. The underlying mechanism of Nopp140 and other factors for regulating agp expression remains unclear. Here we demonstrate that protein kinase A (PKA)-dependent phosphorylation of Nopp140, together with C/EBPbeta, induces agp gene expression synergistically. The cooperative activation of the agp gene by Nopp140 and forskolin is sensitive to inhibition by PKI. Results from biochemical and functional characterizations of Nopp140 mutants defective in PKA phosphorylation sites suggest that PKA-dependent Nopp140 phosphorylation is important for its role in agp gene activation. Furthermore, maximal activation of the agp gene by PKA-phosphorylated Nopp140 depends on the presence of CREB and C/EBPbeta. The participation of CREB in the activation is, however, independent of its PKA-mediated phosphorylation. In summary, we demonstrate the existence of a novel Nopp140-mediated PKA signaling pathway that leads to the activation of agp, one of the major acute phase response genes.
International Committee on Systematics of Prokaryotes Subcommittee on the Taxonomy of Bifidobacterium, Lactobacillus and related organisms. Minutes of the closed meeting by videoconference, 3 September 2020 (2023)

Microbiology Society journals contain high-quality research papers and topical review articles. We are a not-for-profit publisher and we support and invest in the microbiology community, to the benefit of everyone. This supports our principal goal to develop, expand and strengthen the networks available to our members so that they can generate new knowledge about microbes and ensure that it is shared with other communities.
Resilient Adaptive Algebraic Architecture for Parallel Detection and Correction of Soft-Errors (2012)

A novel fault-tolerant microprocessor capable of detecting and correcting radiation-induced soft errors is proposed and evaluated. The Resilient Adaptive Algebraic Architecture performs time redundancy in parallel with matrix multiplication computation, guaranteeing on-the-fly detection and correction of errors disrupting data and logic with minimum overhead. We evaluate the RA <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> microprocessor in terms of performance, area, energy consumption, and fault coverage by performing an extensive design space exploration of the architecture. Finally, we also discuss how the proposed architecture can be used to support a novel hardened-by-construction HW/SW stack based on what we call single-program execution.
Rapid and Simple Detection of a Mycobacterium tuberculosis Circulating Antigen in Serum Using Dot-ELISA for Field Diagnosis of Pulmonary Tuberculosis (2003)

Tuberculosis (TB) has re-emerged as a major health problem worldwide. Developing an easy, inexpensive immunodiagnostic test is extremely important for TB diagnosis, especially in developing countries. A target mycobacterial circulating antigen of 55-kDa molecular weight was identified in sera from confirmed Mycobacterium tuberculosis infected individuals by using Western blotting based on a specific mouse IgG anti-M. tuberculosis monoclonal antibody (TB-55 mAb). No bands were identified in sera of healthy individuals. The target TB antigen was isolated and characterized as a protein. It consists of 15 amino acids; 24.6% of the amino acids are hydrophobic and 46.4% are hydrophilic. A dot-ELISA format, based on TB-55 mAb, was developed for the direct demonstration of the 55-kDa TB antigen in serum samples of pulmonary TB patients. The technical aspects of the developed dot-ELISA are simple, rapid (5 min), and reproducible, as well as sensitive (87%) and specific (93%). Using the more sensitive immunoassay; Western blot, the 55-kDa TB antigen was detected in all (100%) sera that have been shown false negative by dot-ELISA, as well as in true positive sera. In conclusion, we have developed a simple and rapid immunoassay for the direct detection of a circulating mycobacterial antigen in sera of TB infected individuals and, therefore, the developed assay can be applied for laboratory and field diagnosis of TB infection in developing countries.
The impact of the number of cores on tissue microarray studies investigating prostate cancer biomarkers (2011)

Most tissue microarray studies have used a single 0.6-mm tissue core per donor tissue. It has been suggested that multiple cores per donor can increase the representativity of tissue microarray studies. To estimate the potential benefit of multiple cores, we analyzed Ki67 and p53 in triplet cores taken from three different areas of 3,261 prostate cancer tissue blocks. Both p53 and Ki67 labeling index were linked to advanced tumor stage (p<0.0001 each), Gleason score (p<0.0001), and early PSA recurrence (p<0.0001) independently of whether the 3 tissue spots were analyzed separately or combined for a consensus result. The rate of positive findings increased with the amount of analyzed tissue. The average Ki67 labeling index was higher in tumors with 3 interpretable spots (5.3±5.6) as compared to two (4.1±4.7) or one interpretable spot (4.1±4.2, p<0.0001). For p53, tumors with three interpretable spots were positive in 3.8% of cases, and tumors with 1 or 2 interpretable spots in 1.9% only (p=0.003). These data demonstrate that using multiple cores in a tissue microarray does not necessarily increase the ability to identify associations of biomarkers with tumor phenotype and prognosis but has always the disadvantage of additional work and tissue requirements. Multiple cores may even lead to statistical problems if unequal amounts of tissue are analyzed per tumor.
Integrated Economic Statistics for Implementing 2008 SNA (2011)

This paper attempts to discuss issues relating to the development of Integrated Economic Statistics by the National Statistical Offices to overcome the constraints in implementation process of 2008 System of National Accounts and delivering timely, reliable and relevant socio-economic statistics and indicators to the users.
Phase-matching properties and refined Sellmeier equations of the new nonlinear infrared crystal CdSiP_2 (2011)

We directly measured the second harmonic generation and difference frequency generation phase-matching directions of the nonlinear crystal CdSiP(2) until 9.5 μm using the sphere method. The simultaneous fit of the experimental angular data allowed the Sellmeier equations of the ordinary and extraordinary principal refractive indices to be refined over the entire transparency range of the crystal.
Optimal bit allocation in the presence of quantizer feedback (1993)

The authors consider the problem of optimal bit allocation in various forms of predictive coding, where the predictor itself has errors resulting from previous quantization. The solution to this problem has potential application to many forms of image and video coding where predictive coding is used. In predictive coding, the input to the quantizer can be decomposed into the innovation, i.e., the part of the quantizer input signal due to the quantization of the predictor. The natural question that arises is whether it is better to allocate more bits to the predictor, since quantization errors persist longer, or to allocate more bits to coding the total residual. This problem is analyzed for predictive video coding through the use of a simple parametric distortion-rate model for the propagation of quantization errors. This model provides a framework in which the optimal bit allocation problem can be solved in the presence of quantizer feedback. An exact MMSE (minimum mean-square error) solution is obtained that involves solving one nonlinear monotonic equation for one Lagrange multiplier, after which the bit allocation has a closed-form analytic solution. Since the MMSE solution does not produce equal distortion in all frames, the optimal MINMAX (minimize the maximum) bit allocation that minimizes the frame distortion subject to equal distortions per frame is also introduced.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Prevention and early diagnosis of oral cancer – a literature review (2018)

INTRODUCTION: The present study identified and described scientific production on primary and secondary prevention of oral cancer worldwide. This is an integrative review of the literature, focusing on the description of oral cancer prevention experiences.METHODS: The search was performed in the Virtual Health Library (VHL), using the descriptors: early diagnosis, oral neoplasms, primary prevention and secondary prevention. We found 225 articles and selected 22 after evaluation, divided into three themes.RESULTS: Four articles awareness-raising and population-tracking campaigns with the valorization of the role of the dental surgeon and the involvement of health teams. The non-invasive diagnostic methods, considered in fifteen articles, addressed the implementation of new strategies for the early detection of this pathology by different diagnostic methods. The reorganization of the health system (3 articles) encompassed the permanent education of oral health professionals, epidemiological surveillance and reorganization of health services with integration of health care levels. The great majority of the reviewed experiences showed positive results in the prevention of oral cancer. An exception was the active search for suspected cases in the population, since the cost benefit did not compensate the expenditure with human resources for this purpose. The non-invasive methods reported are useful for screening but do not substitute the biopsia for diagnosis.
WMLES Simulations for the 4th High-Lift Prediction Workshop using BCFD (2022)

View Video Presentation: https://doi.org/10.2514/6.2022-3591.vid Wall Modeled Large Eddy Simulation (WMLES) results of the NASA High-Lift Common Research Model are presented at Rec = 5.49 million. Free air simulations are carried out using an ODE-based WMLES capability implemented in the BCFD solver at angles of attack corresponding to Case 2a of AIAA High-Lift Prediction Workshop-4. Overall, WMLES results show reasonably good agreement of aerodynamics coefficients with experimental data demonstrating its improved predictive capabilities compared to RANS at higher angles of attack. The unphysical outboard wing separations seen in RANS solutions are not seen in WMLES solutions. The present free air WMLES simulations under-predict lift coefficient at higher angles of attack and misses the pitch break observed in experimental data post-stall. Flow visualization shows differences in the flow features leading up to stall compared to experimental observation. No significant changes are seen in the aerodynamic coefficients and flow features with a refined grid, potentially indicating the need to include the tunnel wall in the simulation to mimic the experiments. An initial assessment of non-equilibrium wall model effects shows no significant difference compared to an equilibrium wall model solution at a post-stall angle of attack. For an implicit solver, time step and number of iteration per time step play a major role in overall throughput. In this study, it is seen that a time step much larger than the convection rate across a typical cell has an adverse effect on accuracy and with an appropriate time step, 4-orders of magnitude residual drop per time step provides sufficient convergence for an efficient balance of throughput and accuracy for the WMLES simulation.
Robust Volume Control Personalisation from on-Line Preference Feedback (2006)

We describe a learning volume control (LVC) algorithm that learns the volume control operations of a hearing aid user in such a way that the internal settings of the volume control will over time absorb the user's preferences. For practical use, the algorithm should be robust against inconsistent behaviour of the user. We propose two algorithms for LVC (based on LMS learning and Kalman filtering) and demonstrate desirable properties of our LVC in simulations. Further, we provide evidence for the practical relevance of our algorithms in a listening test.
Management: Pros and Cons of Open Plan and Office-based Workplaces (2011)

The debate about the open plan office seems to percolate on slowly each year without ever going anywhere interesting, let alone come to any sort of conclusion. Those in favour of open plan point to greater opportunities to communicate and collaborate in more open environments; those against argue that open plan results in more interruptions and a reduced ability to concentrate.
A Close Relationship between Increases in Galactosyltransferase Activity and the Accumulation of Galactolipids during Plastid Development in Cucumber Seedlings (1995)

Changes in the activity of UDP-galactose:diacylglycerol galactosyltransferase (UDGT), a key enzyme in galactolipid biosynthesis, during germination were investigated in cucumber (Cucumis sativus L. cv. Aonagajibai) seedlings. After germination, UDGT activity increased during growth in darkness for 4 days, reaching 10 times the activity in ungerminated seeds. Illumination of 4-day-old dark-grown seedlings strongly stimulated the activity. By contrast, in seedlings grown continuously in darkness, the increase in UDGT activity ceased after 4 days and the activity remained constant thereafter. A similar increase in the specific activity of UDGT was observed i n the envelope fraction from seedlings, indicating that the increase in the enzymatic activity preceded synthesis of other proteins in the envelope membrane. Coincident with the change in the enzymatic activity, here was an increase in levels of monogalactosyl diacylglycerol (MGDG) and digalactosyl diacylglycerol (DGDG), two major constituents of chloroplast membrane lipids, in the germinated seedlings. Cycloheximide inhibited the light-mediated increase in the enzymatic activity by illumination of 4-day-old dark-grown seedlings, and, as a consequence, it inhibited the accumulation of MGDG and DGDG. It was clear, therefore, that protein synthesis was necessary during this activation. Addition of a cytokinin, benzyladenine (BA), stimulated the increase in the UDGT activity. The increase in the UDGT activity caused by BA was accompanied by the accumulation of galactolipids, as in the case of the activation by light. These results suggest that activation of the final reaction in the synthesis of MGDG, which is catalyzed by the galactosyl-transferase, contributes to the accumulation of galactolipids during the development of the chloroplast membrane.
Micro Fabrication on Glass in the Abrasive Water Jet Process (2004)

A new manufacturing process with abrasive water jet is proposed to fabricate micro channels or dimples on glass. Masks having exposed areas cover the surface so that the covered areas cannot be machined. Because the width of the exposed areas is much smaller than the diameter of the jet nozzle, tapers are made in the cross section of the masks so that abrasive slurry can reach the exposed surface. Abrasive slurry is mixed with water supplied by a low-pressure pump in a water jet nozzle. When abrasive water flows onto the surface vertically between the taper-shaped masks, stagnation is made right under the nozzle. Because the flow velocity is low in stagnation, brittle fracture does not happen on the machined surface. The vertical flow also changes to the horizontal direction at a high velocity out of the stagnation. Abrasive particles, therefore, machine the surface in the horizontal direction at a high velocity. The jet nozzle moves back and forth for several times along the exposed area. A V-shaped groove, which is a depth of 2.5µm and a width of 20µm, can be machined on the surface of fused silica. A micro fabrication machine is made to fabricate micro grooves at the specified positions and angles. It is shown that the machine works well to make micro patterns on the surface in some examples. A machining example proves that the machined shape can be predicted with computational fluid dynamics