gebhart/patrepeval huggingface dataset:
Cytochrome c oxidase in Neurospora crassa contains myristic acid covalently linked to subunit 1. (1995)

Radiolabel from [3H]myristic acid was incorporated by Neurospora crassa into the core catalytic subunit 1 of cytochrome c oxidase (EC 1.9.3.1), as indicated by immunoprecipitation. This modification of the subunit, which was specific for myristic acid, represents an uncommon type of myristoylation through an amide linkage at an internal lysine, rather than an N-terminal glycine. The [3H]myristate, which was chemically recovered from the radiolabeled subunit peptide, modified an invariant Lys-324, based upon analyses of proteolysis products. This myristoylated lysine is found within one of the predicted transmembrane helices of subunit 1 and could contribute to the environment of the active site of the enzyme. The myristate was identified by mass spectrometry as a component of mature subunit 1 of a catalytically active, purified enzyme. To our knowledge, fatty acylation of a mitochondrially synthesized inner-membrane protein has not been reported previously.
Illumination Face Spaces Are Idiosyncratic. (2006)

Illumination spaces capture how the appearances of human faces vary under changing illumination. This work models illumination spaces as points on a Grassmann manifold and uses distance measures on this manifold to show that every person in the CMU-PIE and Yale data sets has a unique and identifying illumination space. This suggests that variations under changes in illumination can be exploited for their discriminatory information. As an example, when face recognition is cast as matching sets of face images to sets of face images, subjects in the CMU-PIE and Yale databases can be recognized with 100 % accuracy. 1.
Methane Hydrates (2014)

Gas hydrate is a solid, naturally occurring substance consisting predominantly of methane gas and water. Recent scientific drilling programs in Japan, Canada, the United States, Korea and India have demonstrated that gas hydrate occurs broadly and in a variety of forms in shallow sediments of the outer continental shelves and in Arctic regions. Field, laboratory and numerical modelling studies conducted to date indicate that gas can be extracted from gas hydrates with existing production technologies, particularly for those deposits in which the gas hydrate exists as pore-filling grains at high saturation in sand-rich reservoirs. A series of regional resource assessments indicate that substantial volumes of gas hydrate likely exist in sand-rich deposits. Recent field programs in Japan, Canada and in the United States have demonstrated the technical viability of methane extraction from gas-hydrate-bearing sand reservoirs and have investigated a range of potential production scenarios. At present, basic reservoir depressurisation shows the greatest promise and can be conducted using primarily standard industry equipment and procedures. Depressurisation is expected to be the foundation of future production systems; additional processes, such as thermal stimulation, mechanical stimulation and chemical injection, will likely also be integrated as dictated by local geological and other conditions. An innovative carbon dioxide and methane swapping technology is also being studied as a method to produce gas from select gas hydrate deposits. In addition, substantial additional volumes of gas hydrate have been found in dense arrays of grain-displacing veins and nodules in fine-grained, clay-dominated sediments; however, to date, no field tests, and very limited numerical modelling, have been conducted with regard to the production potential of such accumulations. Work remains to further refine: (1) the marine resource volumes within potential accumulations that can be produced through exploratory drilling programs; (2) the tools for gas hydrate detection and characterisation from remote sensing data; (3) the details of gas hydrate reservoir production behaviour through additional, well-monitored and longer duration field tests and (4) the understanding of the potential environmental impacts of gas hydrate resource development. The results of future production tests, in the context of varying market and energy supply conditions around the globe, will be the key to determine the ultimate timing and scale of the commercial production of natural gas from gas hydrates.
Fundamental Differences of Substrate Hydroxylation by High-Valent Iron(IV)-Oxo Models of Cytochrome P450 (2009)

An Iron(IV)-oxo heme(+*) complex (Compound I, Cpd I) is the proposed active species of heme enzymes such as the cytochromes P450 and is elusive; therefore, biomimetic studies on active site mimics give valuable insight into the fundamental properties of heme active species. In this work we present density functional theory (DFT) calculations on substrate hydroxylation by a Compound I mimic [Fe(IV)=O(Por(+*))Cl] and its one-electron reduced form [Fe(IV)=O(Por)Cl](-). Thus, recent experimental studies showed that [Fe(IV)=O(Por)Cl](-) is able to react with substrates via hydride transfer reactions [Jeong, Y. J.; Kang, Y.; Han, A.-R.; Lee, Y.-M.; Kotani, H.; Fukuzumi, S.; Nam, W. Angew. Chem., Int. Ed. 2008, 47, 7321-7324]. By contrast, theoretical studies on camphor hydroxylation by these two oxidants concluded that the one-electron reduced form of Compound I is a sluggish oxidant of hydroxylation reactions [Altun, A.; Shaik, S.; Thiel, W. J. Am. Chem. Soc. 2007, 129, 8978-8987]. To resolve the question why the one-electron reduced Compound I is an oxidant in one case and a sluggish oxidant in other cases, we have performed a DFT study on 10-methyl-9,10-dihydro acridine (AcrH(2)) hydroxylation by [Fe(IV)=O(Por(+*))Cl] and [Fe(IV)=O(Por)Cl](-). The calculations presented in this work show that both [Fe(IV)=O(Por(+*))Cl] and [Fe(IV)=O(Por)Cl](-) are plausible oxidants, but [Fe(IV)=O(Por(+*))Cl] reacts via much lower reaction barriers. Moreover, [Fe(IV)=O(Por(+*))Cl] reacts via hydride transfer, while [Fe(IV)=O(Por)Cl](-) by hydrogen abstraction. The differences between hydride and hydrogen atom transfer reactions have been rationalized with thermodynamic cycles and shown to be the result of differences in electron abstraction abilities of the two oxidants. Thus, the calculations predict that [Fe(IV)=O(Por)Cl](-) is only able to hydroxylate weak C-H bonds, whereas [Fe(IV)=O(Por(+*))Cl] is more versatile.
Tracking your browser with high-performance browser fingerprint recognition model (2020)

As the cyber security has attracted great attention in recent years, and with all kinds of tools' (such as Network Agent, VPN and so on) help, traditional methods of tracking users like log analysis and cookie have been not that effective. Especially for some privacy sensitive users who changed their browser configuration frequently to hide themselves. The Browser Fingerprinting technology proposed by Electronic Frontier Foundation (EFF) gives a new approach of tracking users, and then our team designed an enhanced fingerprint dealing solution based on browser fingerprinting technology. Our enhanced solution plays well in recognizing the similar fingerprints, but it is not that efficient. Nowadays we improve the algorithm and propose a high-performance, efficient Browser Fingerprint Recognition Model. Our new model reforms the fingerprint items set by EFF and propose a Fingerprint Tracking Algorithm (FTA) to deal with collected data. It can associate users with some browser configuration changes in different periods of time quickly and precisely. Through testing with the experimental website built on the public network, we prove the high-performance and efficiency of our algorithm with a 20% time-consuming decrease than ever.
Synergistic Integration of C12–C16 Cationic Surfactants for Flocculation and Lipid Extraction from Chlorella Biomass (2016)

Microalgae lipids could be a good alternative feedstock for liquid fuel, but complex processing steps with significant energy demands present roadblocks. Combining biomass harvesting and lipid recovery into one simple step can lower complexity and energy costs. This study evaluated the use of C12–C16 cationic surfactants in this synergistic manner. First, we determined that a dose as low as 0.45 mM of C16-alkyl-chain cationic surfactant (hexadecyltrimethylammonium, CTAB) led to >85% biomass-harvesting rate for Chlorella biomass, and good harvest was correlated to a slightly positive zeta potential. Second, the cationic surfactants disrupted cell structures (detected by transmission electron microscopy) and led to lipid recovery (measured as fatty acid methyl esters, FAME) as high as 90% using nontoxic ethyl acetate (EA) as the solvent and without altering the FAME distribution; for context, EA was able to extract less than 1% of FAME from control (not surfactant-treated) Chlorella. Disruption and high FAME yield were associated with surfactants’ critical micelle concentration (CMC): a lower CMC required a lower concentration of surfactant to disrupt the cells. The synergistic benefits of cationic surfactants can be attained by maintaining a slightly positive zeta potential for effective flocculation and adding the minimum concentration of surfactant needed for cell disruption.
Message handling systems and application layer communication protocols : proceedings of the IFIP WG 6.5 International Symposium on Message Handling Systems and Application Layer Communication Protocols, Zurich, Switzerland, 3-5 October 1990 (1991)

Application Layer Communication Services. Authentication and Security Standards. Interworking. Group Communication and Computer Conferencing Systems. Message Store and Message Archive. Messaging and People. Messaging and Document Processing. System Design and Implementation. Directory. Security. Application Layer Communication Protocols. Results from the Workshop Discussions. Panel: OSI Application Architecture, is it a Success?
Ride Quality and Guide Rail Durability Improvement by Active Steering System for AGT Vehicle (2004)

This paper describes design of active steering system for Automated Guideway Transit (AGT) vehicles. The modeling of the AGT vehicles with active steering system is carried out first. The constructed vehicle model includes lateral transition, roll and yaw motion for vehicle body, front bogie and rear bogie, respectively. The dynamics of actuator that produce the steering torque is also considered. PID controller is used to control the active steering system. It is shown that the active steering system is effective for ride quality improvement of AGT Vehicle.It is. shown that the active steering system is effective for ride quality and guide rail durability improvement of AGT Vehicle.
Pathogenicity Enhancement ofMetarhizium anisopliaeandBeauveria bassianato First Instars ofDiaprepes abbreviatus(Coleoptera: Curculionidae) with Sublethal Doses of Imidacloprid (1997)

Journal Article Pathogenicity Enhancement of Metarhizium anisopliae and Beauveria bassiana to First Instars of Diaprepes abbreviatus (Coleoptera: Curculionidae) with Sublethal Doses of Imidacloprid Get access Eliane D. Quintela, Eliane D. Quintela 1 Institute of Food and Agricultural Sciences, Citrus Research and Education Center, University of Florida, 700 Experiment Station Road, Lake Alfred, FL 33850 1 Empresa Brasileirade Pesquisa Agropecuária/Centro Nacional de Pesquisa de Arroz e Feijão (CNPAF), Cx.P.179, 74001-970, Goiâfmia, GO, Brasil Search for other works by this author on: Oxford Academic PubMed Google Scholar Clayton W. Mccoy Clayton W. Mccoy 2 Institute of Food and Agricultural Sciences, Citrus Research and Education Center, University of Florida, 700 Experiment Station Road, Lake Alfred, FL 33850 2 Citrus Research and Education Center, University of Florida, 700 Experiment Station Road, Lake Alfred, FL 33850 Search for other works by this author on: Oxford Academic PubMed Google Scholar Environmental Entomology, Volume 26, Issue 5, 1 October 1997, Pages 1173–1182, https://doi.org/10.1093/ee/26.5.1173 Published: 01 October 1997 Article history Received: 20 January 1996 Accepted: 09 June 1997 Published: 01 October 1997
The distribution of IgE plasma cells in lymphoid and non-lymphoid tissues of high-IgE responder rats: differential localization of antigen-specific and 'bystander' components of the IgE response to inhaled antigen. (1992)

Repeated exposure of high-IgE responder rats to antigen-containing aerosols stimulates IgE responses which last for several weeks, and are eventually terminated with the onset of immunological tolerance. Studies on the distribution of total and antigen-specific IgE plasma cells and IgE mRNA during antibody production, identified the lymph nodes draining the lower respiratory tract as the primary site for initiation of the IgE response to inhaled antigen; subsequently the response seeded to mucosa-associated lymph nodes but not to central lymphoid organs. A vigorous 'bystander' IgE response (approx. x 10 the specific response) was also observed, but this was restricted to areas directly draining sites of deposition of inhaled antigen, including non-lymphoid respiratory mucosal tissues. Despite the rapid termination of the specific IgE response after the fourth week of exposure, the bystander component persisted. These results are discussed in relation to the role of cognate/non-cognate T-B interactions in the IgE response to inhaled antigens, and the relative susceptibility of each component to T-cell regulation in vivo.
Transitive inference after minimal training in rhesus macaques (Macaca mulatta). (2021)

Rhesus macaques, when trained for several hundred trials on adjacent items in an ordered list (e.g., A > B, B > C, C > D), are able to make accurate transitive inferences (TI) about previously untrained pairs (e.g., A > C, B > D). How that learning unfolds during training, however, is not well understood. We sought to measure the relationship between the amount of TI training and the resulting response accuracy in 4 rhesus macaques using seven-item lists. The training conditions included the absolute minimal case of presenting each of the six adjacent pairs only once prior to testing. We also tested transfer to nonadjacent pairs with 24 and 114 training trials. Because performance during and after small amounts of training is expected to be near chance levels, we developed a descriptive statistical model to estimate potentially subtle learning effects in the presence of much larger random response variability and systematic bias. These results suggest that subjects learned serial order in an incremental fashion. Thus, rather than performing transitive inference by a logical process, serial learning in rhesus macaques proceeds in a manner more akin to a statistical inference, with an initial uncertainty about list position that gradually becomes more accurate as evidence accumulates. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
Performance of a simplified low-flow rate cold-water deaerator (1962)

http://deepblue.lib.umich.edu/bitstream/2027.42/3195/5/bab0009.0001.001.pdf
WS2 Nanotube Bundles and Foils (2002)

WS2 nanotubes were synthesized in large amounts by reaction of H2S with WO3 nanopowder using a fluidized-bed reactor. The nanotubes come often in a few centimeter long bundles or alternatively as a few centimeters large foil deposited on the quartz wall of the reactor. Transmission electron microscopy revealed that the open-ended nanotubes are quite uniform in shape: up to 0.5-mm long and 15−20 nm in diameter, and they are chiral.
Active Flow Control for Practical High-Lift Systems (2007)

The application of active flow control for high-lift multi-element wing sections is investigated. A computational fluid dynamics procedure is used to simulate the interactive flow in conjunction with distributed flow control. Favorable nonlinear interactions using flow control on a conventional wing section and an advanced airfoil lead to major aerodynamic performance improvements at representative takeoff and landing conditions. This study demonstrates that judicious application of flow control at select locations on the individual wing elements may lead to near inviscid lift levels in the linear lift range and substantial gains in maximum lift.
A Simple Formula to Calculate Shallow-Water Transmission Loss by Means of a Least-Squares Surface Fit Technique. (1980)

A semi-empirical formula TL = 15 log R + (A + B(log f) + C(log f) sq) R + D (in dB) is proposed to express sound transmission loss in shallow water as a function of range and frequency. The four coefficients A, B, C and D are determined from either experimental or model data by the use of a least-squares surface fit and the formula usually gives a standard derivation of the order of a few dB. The formula can be used for studying system performances, sonar range predictions, and as a compact data storage. (Author)
Gut Hormones and ‘Minimal Enteral Feeding’ (1986)

Previously we have identified multiple surges in plasma concentrations of gut hormones postnatally in enterally fed term and preterm infants. In this study on 104 preterm infants we have shown that such surges are induced after ingestion of very small quantities of human milk. Whereas 6-day-old exclusively parenterally fed infants showed no postnatal elevation in enteroglucagon, gastrin, GIP, motilin and neurotensin, infants recovering from hyaline membrane disease who had received restricted enteral nutrition had similar hormone surges to those seen in well infants on full enteral feeds. Significant elevations in enteroglucagon, gastrin and GIP occurred after a cumulative mean enteral feed volume since birth of only 24 ml (12 ml/kg body weight) had been consumed and after a mean total intake of 96 ml (50 ml/kg) the response was maximal. Greater feed volumes were required to produce a neurotensin or motilin surge, but even these volumes were substantially lower than those required for full enteral feeding. In view of the proposed roles of gut hormones in the adaptation to extrauterine nutrition these data have implications for mammalian biology and raise the possibility that 'minimal enteral feeding' might have a clinical therapeutic role in infants undergoing prolonged parenteral nutrition.
Preview Ride Comfort Control for Electric Active Suspension (eActive3) (2014)

&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;This paper reports the results of a study into a preview control that uses the displacement of the road surface in front of the vehicle to improve for front and rear actuator responsiveness delays, as well as delays due to calculation, communication, and the like. This study also examined the effect of a preview control using the eActive3 electric active suspension system, which is capable of controlling the roll, pitch, and warp modes of vehicle motion.&lt;/div&gt;&lt;/div&gt;
The mass, metabolism and length explanation can simultaneously calculate an animal’s mass and metabolic rate from its characteristic length (2016)

It is shown that the mass, metabolism and length explanation (MMLE) can simultaneously compute an animal’s body mass and BMR given its characteristic length using data for humans. MMLE was advanced in 1984 to explain the relationship between metabolic rate and body mass for birds and mammals. It was modernized in 2015 by explicitly treating dynamic similarity of mammals’ skeletal musculature and revising the treatment of BMR. Using two primary equations MMLE deterministically computes the absolute value of Basal Metabolic Rate (BMR) and body mass for individual animals as functions of an individual animal’s characteristic length and sturdiness factor. The characteristic length is a measureable skeletal length associated with an animal’s means of propulsion. The sturdiness factor expresses how sturdy or gracile an animal is. Eight other parameters occur in the equations that vary little among animals in the same phylogenetic group. A mass and length data set with 575 entries from the orders Rodentia, Chiroptera, Artiodactyla, Carnivora, Perissodactyla and Proboscidea and a BMR and mass data set with 436 entries from the orders Rodentia, Chiroptera, Artiodactyla and Carnivora were used to estimate values for the parameters occurring in the equations. With the estimated values MMLE can exactly compute every BMR and mass datum from the BMR and mass data set. Furthermore, MMLE can exactly compute every body mass datum from the mass and length data set. Since there is not a data set that simultaneously reports body mass, BMR and characteristic length for individual animals from the mammal orders that were analyzed it could not be determined whether or not MMLE could simultaneously compute both an animal’s BMR and body mass given its characteristic length. There are large data sets that report body mass, BMR and height for humans. A human’s characteristic length can be estimated from height. In this paper human data categorized by sex, age and body mass index (BMI) are used to show that MMLE can indeed simultaneously compute a human’s body mass and BMR given his or her characteristic length. The MMLE body mass equation is modified to explicitly address body fat because it appears that humans are fatter than other running/walking placental mammals. Differences in body fat seem to account for body mass and BMR sexual dimorphism among humans. The impact on BMR of the large and metabolically expensive human brain is addressed. Also mitochondria capability decline with age is addressed.
Functional heterogeneity of alloantibodies against the human platelet antigen (HPA)-1a (2005)

The integrin alphaIIbbeta is the major fibrinogen receptor on the platelet membrane and plays a crucial role for platelet aggregation. The beta3-subunit carries the human platelet alloantigen (HPA)-1a, which is the main target for alloantibodies (alloabs) responsible for foetal and neonatal alloimmune thrombocytopenia (FNAIT) and post-transfusion purpura (PTP). Whereas PTP is almost invariably associated with severe bleeding, the clinical presentation of FNAIT ranges from mild thrombocytopenia to severe haemorrhagic diathesis. However, this clinical heterogeneity is not fully understood as it is not explained solely by the variability of the platelet count. Here, we examined the ability of HPA-1a alloabs from mothers with FNAIT (n = 43) and PTP patients (n = 8) to inhibit cell adhesion to fibrinogen and asked if this inhibition was correlated with the heterogeneity of the clinical picture. Stably transfected cells expressing HPA-1a (beta3-Leu33) and -1b (beta3-Pro33) isoforms were incubated with sera containing HPA-1a alloabs and were allowed to adhere to immobilised fibrinogen. The inhibitory activity was measured as percentage of cell adhesion in the presence of patient sera versus normal AB serum. Only two FNAIT sera specifically inhibited the adhesion of HPA-1a, but not HPA-1b cells. Two other FNAIT sera blocked the adhesion of HPA-1a as well as HPA-1b cells. Interestingly, all four neonates with inhibitory HPA-1a alloabs (9% of all sera) suffered severe bleeding. In comparison, the majority of PTP sera (75%) inhibited cell binding to fibrinogen, four PTP sera selectively inhibited the adhesion of HPA-1a cells whilst 2 sera impaired the binding of both allotypes. Our observations indicate that 1) HPA-1a alloabs are heterogeneous in their ability to interfere with fibrinogen binding, and 2) inhibition of the alphaIIbbeta3 fibrinogen receptor by HPA-1a alloabs may contribute to pronounced bleeding in patients with alloimmune thrombocytopenia.
Preparation and photoluminescence study of patterned substrate quantum wires (2011)

GaAs/AlGaAs quantum wires grown by molecular beam epitaxy on a V-groove patterned substrate was described. The cross section of scan electron microscopy (SEM) image shows that crescent-type quantum wire were formed at the V groove bottom, which is a triangle of about 60nm in width and 14nm in height. Two peaks at 793.7nm and 799.5nm of photoluminescence spectrum at 87K verified the existence of quantum wires. Theoretical calculation gives 8meV blue shift, which is proved to be casued by lateral confinement compared with quantum well of the same width.