gebhart/patrepeval huggingface dataset:
Driver sleepiness - Comparisons between young and older men during a monotonous afternoon simulated drive (2012)

Young male drivers feature predominately in road crash statistics, especially where the driver has\nfallen asleep. One possibility is that they are more vulnerable to the effects of sleep loss\ncompared with older men. We assessed the effect of normal night sleep versus prior sleep\nrestricted to 5h, in a counterbalanced design, on prolonged afternoon driving in 20 younger (av.\n23y) and 20 older (av. 67y) healthy men who drove a full size, real car simulator under\nmonotonous ‘motorway’ conditions for 2h during the ‘afternoon dip’. Driving was monitored for\nsleepiness related lane deviations, EEGs were recorded continuously and subjective ratings of\nsleepiness taken every 200sec throughout the drive. Following normal sleep there were no\ndifferences between groups for any measure. After sleep restriction, and compared with the older\ngroup, the younger drivers showed significantly more sleepiness-related deviations, greater 4-11Hz\nEEG power, and a near significant increase of subjective sleepiness. Correlations between the\nEEG and subjective measures were highly significant for both groups, indicating good self-insight\ninto increasing sleepiness. This study confirms the greater vulnerability of younger drivers to sleep\nloss under prolonged driving, even during the early afternoon.
ChemInform Abstract: Total Synthesis of (‐)‐Motuporin. (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Regenerating Agricultural Landscapes with Perennial Groundcover for Intensive Crop Production (2019)

The Midwestern U.S. landscape is one of the most highly altered and intensively managed ecosystems in the country. The predominant crops grown are maize (Zea mays L.) and soybean [Glycine max (L.) Merr]. They are typically grown as monocrops in a simple yearly rotation or with multiple years of maize (2 to 3) followed by a single year of soybean. This system is highly productive because the crops and management systems have been well adapted to the regional growing conditions through substantial public and private investment. Furthermore, markets and supporting infrastructure are highly developed for both crops. As maize and soybean production have intensified, a number of concerns have arisen due to the unintended environmental impacts on the ecosystem. Many areas across the Midwest are experiencing negative impacts on water quality, soil degradation, and increased flood risk due to changes in regional hydrology. The water quality impacts extend even further downstream. We propose the development of an innovative system for growing maize and soybean with perennial groundcover to recover ecosystem services historically provided naturally by predominantly perennial native plant communities. Reincorporating perennial plants into annual cropping systems has the potential of restoring ecosystem services without negatively impacting grain crop production and offers the prospect of increasing grain crop productivity through improving the biological functioning of the system.
간 ( 肝 ) 이식후 Primary Dysfunction of Graft에 대한 Prostaglandin의 치료 효과 (1995)

Primary graft non-function (PNF) remains one of the most life-threatening problems after liver transplantation. Untreated, it has a mortality of near 100% and to date the only treatment has been retransplantation. However, Urgent retransplantation in Korea is almost impossible due to the difficulty in obtaining donor organs. Recently, Prostaglandins of the E series have been used in the treatment of primary graft non-function or dysfunction after solid organ transplantation. We experienced a case of primary dysfunction of a liver graft which was successfully treated with continuous infusion of PGE1. PCE1 may have an important role in the management of PNF in liver transplantation, considering the difficulty of obtaining donor livcrs for urgent retransplantation in our country.
EULERIAN-LAGRANGIAN APPROACH TO MODELING HEAT TRANSFER IN GAS-PARTICLE MIXTURES: VOLUME-AVERAGED EQUATIONS, MULTI-SCALE MODELING AND COMPARISON WITH NUMERICAL EXPERIMENTS (2018)

International audience
Supplementary Figure 1 from Cell Intrinsic Role of COX-2 in Pancreatic Cancer Development (2023)

&lt;p&gt;PDF file, 275K, GRP78 expression in human and mouse PDAC.&lt;/p&gt;
Serological detection of ‘Candidatus Liberibacter asiaticus’ in citrus, and identification by GeLC-MS/MS of a chaperone protein responding to cellular pathogens (2016)

We describe experiments with antibodies against 'Candidatus Liberibacter asiaticus used to detect the pathogen in infected plants. We used scFv selected to bind epitopes exposed on the surface of the bacterium in tissue prints, with secondary monoclonal antibodies directed at a FLAG epitope included at the carboxyl end of the scFv. Unexpectedly, the anti-FLAG secondary antibody produced positive results with CaLas diseased samples when the primary scFv were not used. The anti-FLAG monoclonal antibody (Mab) also identified plants infected with other vascular pathogens. We then identified a paralogous group of secreted chaperone proteins in the HSP-90 family that contained the amino acid sequence DDDDK identical to the carboxy-terminal sequence of the FLAG epitope. A rabbit polyclonal antibody against one of the same epitopes combined with a goat anti-rabbit secondary antibody produced very strong purple color in individual phloem cells, as expected for this pathogen. These results were entirely specific for CaLas-infected citrus. The simplicity, cost and ability to scale the tissue print assay makes this an attractive assay to complement PCR-based assays currently in use. The partial FLAG epitope may itself be useful as a molecular marker for the rapid screening of citrus plants for the presence of vascular pathogens.
Colloidal Quantum Dot Tandem Solar Cells Using CVD Graphene as An Atomically Thin Intermediate Recombination Layer (2019)

Two-terminal tandem cell architectures are believed to be an effective way to further improve the power conversion efficiency in solution processed photovoltaics. To design an efficient tandem solar cell, two key issues need to be considered. Firstly, subcells with well-matched currents and complementary absorption characteristics are a prerequisite for high efficiency. Secondly identifying the appropriate intermediate layer (IML) to connect the subcells is necessary to minimize the optical and electronic losses. PbS colloidal quantum dots (CQDs) are a notable choice for the subcells due to their low cost, solution processibility and remarkable wide range band gap tunability. Single layer Graphene (Gr) has been proposed to be a promising IML due to its high transparency and conductivity. Here, as a proof of concept, we demonstrate a solution processed two terminal PbS CQDs tandem solar cell employing chemical vapor deposited Gr as the IML. In doing so, we report a PbS CQD cell comprising subcells with bandgaps of 1.4 and 0.95 eV that delivers power conversion efficiency in excess of 7%, substantially higher than previously reported CQD tandem cells.
Diabetic kidney lesions of GIPRdntransgenic mice: podocyte hypertrophy and thickening of the GBM precede glomerular hypertrophy and glomerulosclerosis (2009)

Diabetic nephropathy is the leading cause of end-stage renal disease and the largest contributor to the total cost of diabetes care. Rodent models are excellent tools to gain more insight into the pathogenesis of diabetic nephropathy. In the present study, we characterize the age-related sequence of diabetes-associated kidney lesions in GIPR(dn) transgenic mice, a novel mouse model of early-onset diabetes mellitus. Clinical-chemical analyses as well as qualitative and quantitative morphological analyses of the kidneys of GIPR(dn) transgenic animals and nontransgenic littermate controls were performed at 3, 8, 20, and 28 wk of age. Early renal changes of transgenic mice consisted of podocyte hypertrophy, reduced numerical volume density of podocytes in glomeruli, and homogenous thickening of the glomerular basement membrane, followed by renal and glomerular hypertrophy as well as mesangial expansion and matrix accumulation. At 28 wk of age, glomerular damage was most prominent, including advanced glomerulosclerosis, tubulointerstitial lesions, and proteinuria. Real-time PCR demonstrated increased glomerular expression of Col4a1, Fn1, and Tgfb1. Immunohistochemistry revealed increased mesangial deposition of collagen type IV, fibronectin, and laminin. The present study shows that GIPR(dn) transgenic mice exhibit renal changes that closely resemble diabetes-associated kidney alterations in humans. Data particularly from male transgenic mice indicate that podocyte hypertrophy is directly linked to hyperglycemia, without the influence of mechanical stress. GIPR(dn) transgenic mice are considered an excellent new tool to study the mechanisms involved in onset and progression of diabetic nephropathy.
Semiconducting properties of a low resistive Ca-doped YIG film (1982)

A low resistivity p-semiconductor Ca:YIG film containing Fe4+ ions has been investigated. In particular, the temperature dependence, the magnetogradient conductivity, and the bolometer responsivity of this material have been analyzed in detail. Main results can be summarized as: (i) a large increase of the conductivity causing a negative magnetoresistance of 26% for gradient field of 1500 G/cm; (ii) high responsivity values exhibited by this material when it is used in bolometer applications where resistance temperature coefficient of about −0.04/°C has been measured.
Enumeration of CD34+ Hematopoietic Progenitor Cells in Peripheral Blood and Leukapheresis Products by Microvolume Fluorimetry: A Comparison with Flow Cytometry (1997)

There is increasing interest in both standardization and simplification of methods for enumeration of CD34+ hematopoietic progenitor cells (HPC) to facilitate cellular therapies and to improve interinstitutional comparison of clinical and laboratory results. We evaluated a novel method for CD34+ cell enumeration based on microvolume fluorimetry (MVF) compared with our laboratory's routine flow cytometric method on samples of peripheral blood and leukapheresis products. The MVF method is semiautomated and uses a 633-nm light from a helium-neon laser to scan fluorochrome-labeled cells held in stasis in a capillary known volume. The performance of the MVF assay for enumeration of CD34+ cells was found to be comparable to our routine flow cytometric assay in linearity and accuracy in the range of 5-1500 cells per microliter. Precision of MVF for replicate assays on the same instrument was demonstrated by coefficient of variation (CV) values of 8.4% at a CD34+ cell concentration of 284/microliters for a sample volume of 0.8 microliters, and 15.7% at 12/microliters for a sample volume of 3.2 microliter. Precision among three different instruments was demonstrated, using sample volumes of 1.6 microliters, by CV values of 44% at 6 cells/microliters and 4.6% at 733 cells/microliters. In a field sample evaluation, precision of the entire assay system for paired measurements on 0.8-microliter sample volumes was demonstrated by CV values of 50%, 31%, and 15% for peripheral blood samples with concentrations of 0-10, 10-20, and 20-100 CD34+ cells/microliters, respectively, and 6.3%, 8.1% and 6.5% for leukapheresis samples with concentrations of 0-100, 100-1,000, and 1,000-2,500 CD34+ cells/microliters, respectively. The MVF assay was easy to perform, required minimal technical training time, and had a turnaround time of 40 min, of which less than 10 min was actual technical time. These observations suggest that the MVF method for CD34+ cell enumeration may prove useful to clinical laboratories providing support for HPC collection, processing, and transplantation services that require relatively simple, rapid assays for product quality control or to guide real-time clinical decisions.
The relaxation behavior of polymer glass based on polymethylmethacrylate and its consideration in the strength calculation of aircraft glazing (2017)

The temperature–deformation–time dependences of the physical and mechanical characteristics of polymer glass based on polymethylmethacrylate necessary for the strength calculation of glazing were experimentally determined. The calculation of the residual and temperature stresses in a glazing element made of VOS-2 heat-resistant copolymer glass was performed. Ways to decrease the stresses that occur under operation by developing materials with decreased values of the elastic modulus and the temperature coefficient of linear expansion were proposed. The work was performed within complex research trend 15.4 [1] Optical Materials and Glazing Materials (“Strategic Trend of Development of Materials and Technologies for Their Processing for the Period to 2030”).
Synthesis and DNA binding and photonicking properties of acridine orange linked by a polymethylene tether to (1,2-diaminoethane)dichloroplatinum(II) (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and DNA binding and photonicking properties of acridine orange linked by a polymethylene tether to (1,2-diaminoethane)dichloroplatinum(II)Bruce E. Bowler, L. Steven Hollis, and Stephen J. LippardCite this: J. Am. Chem. Soc. 1984, 106, 20, 6102–6104Publication Date (Print):October 1, 1984Publication History Published online1 May 2002Published inissue 1 October 1984https://pubs.acs.org/doi/10.1021/ja00332a070https://doi.org/10.1021/ja00332a070research-articleACS PublicationsRequest reuse permissionsArticle Views372Altmetric-Citations67LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Nitrogen Doping into TiO 2 and Loading of Co‐Catalysts for Enhanced Photocatalysis Under Visible‐Light Irradiation (2023)

Nitrogen doping of titanium dioxide (N-TiO 2 ) boosts TiO 2 photocatalyst toward the visible light region of up to 520 nm by forming an N 2p state in the band gap. Co-catalysts loading with Cu, Fe, and Pt on the N-TiO 2 surface further enhances photocatalytic activity under visible light irradiation, which enabled the use in various practical applications for indoor use.
Cosmic-Ray Spectra in Interstellar Space (2004)

At energies below ∼300 MeV/nuc our knowledge of cosmic‐ray spectra outside the heliosphere is obscured by the energy loss that cosmic rays experience during transport through the heliosphere into the inner solar system. This paper compares measurements of secondary electron‐capture isotope abundances and cosmic‐ray spectra from ACE with a simple model of interstellar propagation and solar modulation in order to place limits on the range of interstellar spectra that are compatible with both sets of data.
Study of selectively reflecting characteristics of polymer stabilised chiral nematic liquid crystal films with a temperature-dependent pitch length (2010)

Chiral propane-1,2-di-(4-(4-heptylcyclohexyl)benzoate) (PPCB) and 1-phenylethane-1,2-di-(4-(4-heptylcyclohexyl) benzoate) (PEPB) were synthesised and used as chiral dopants to induce chiral nematic liquid crystals (N*-LCs). Since the helical twisting power of the former first decreased and then increased as a result of thermally induced inversion helicity sense, and those of the latter changed little with increasing temperature, the pitch lengths of the N*-LCs prepared from (N-LC)/PPCB/(R)-PEPB and N-LC/PPCB/(S)-PEPB mixtures decreased and increased with increasing temperature respectively. Then, based on these two kinds of N*-LCs, polymer stabilised liquid crystal films were obtained, in which the bandwidth of the selective reflection spectra increased with increasing temperature.
Flexible Fractal Electromagnetic Bandgap for Millimeter-Wave Wearable Antennas (2018)

This letter presents a novel design of a uniplanar compact electromagnetic bandgap (EBG) for millimeter-wave wearable antennas. The unit cell of the EBG has a flexible fractal design with self-similar window-like structure, which can be easily fabricated at millimeter scale. The fabricated EBG is a 3 × 3 cell array laser-cut from adhesive copper foil on polyester fabric substrate. Results show that the gain and -10 dB bandwidth of a wearable coplanar waveguide (CPW) antenna backed by the proposed EBG are improved by 3 dB and 40%, respectively, across the frequency range from 20 to 40 GHz. Backward radiation is also decreased by 15 dB, significantly reducing the potential health risk posed by the radiating antenna to the human wearer. Furthermore, on-body measurements show that the CPW-EBG antenna performances are not highly sensitive to human body proximity.
Notice of Retraction: Management on technology alliance of high-tech enterprises (2011)

Retracted.
The Heat of Adsorption of a Boundary Lubricant (1960)

For the case of physical bonding, the heat of adsorption of a boundary lubricant on a bearing surface has been shown to determine frictional behavior. The theory is here extended to include the effects of temperature and velocity on wear, and corresponding experimental results are presented. The mathematical form of these dependencies is discussed and a characteristic temperature defined and calculated. As a result, a class of very high temperature boundary lubricants is suggested and some further experimental results summarized.
Virtual scanning tunneling microscopy: A local spectroscopic probe of two-dimensional electron systems (2010)

We propose a probe technique capable of performing local low-temperature spectroscopy on a two-dimensional electron system (2DES) in a semiconductor heterostructure. Motivated by predicted spatially-structured electron phases, the probe uses a charged metal tip to induce electrons to tunnel locally, directly below the tip, from a “probe” 2DES to a “subject” 2DES of interest. We test this concept with large-area (nonscanning) tunneling measurements, and predict a high spatial resolution and spectroscopic capability, with minimal influence on the physics in the subject 2DES.
The Spanish Presidency and CSDP: Time to Get Serious about the Union¿s Military Planning and Conduct Capability (2010)

This ARI provides an overview of the EU�s capability for the planning, command and control of CSDP military operations and offers some practical recommendations. It argues that the lack of a permanent operational planning capability hampers flexibility in the Union�s planning process, as politico-strategic deliberations over potential CSDP missions lack the crucial operational expertise necessary to address crucial political questions, such as how many troops are needed and for how long or how much the mission will cost. Secondly, the lack of an operational planning capability denies the Union the capacity to develop (advance) contingency planning products, that are so crucial in situations where rapid reaction is required. Finally, the lack of a permanent command and control infrastructure has a negative impact upon the quality and security of the Union�s military Communication and Information Systems (CIS) and hampers the kind of overall situational awareness offered by a central command, so vital for a Union that aims to think more strategically (as argued in the 2008 revision of the European Security Strategy).
Central exogenous nitric oxide decreases cardiac sympathetic drive and improves baroreflex control of heart rate in ovine heart failure (2014)

Heart failure (HF) is associated with increased cardiac and renal sympathetic drive, which are both independent predictors of poor prognosis. A candidate mechanism for the centrally mediated sympathoexcitation in HF is reduced synthesis of the inhibitory neuromodulator nitric oxide (NO), resulting from downregulation of neuronal NO synthase (nNOS). Therefore, we investigated the effects of increasing the levels of NO in the brain, or selectively in the paraventricular nucleus of the hypothalamus (PVN), on cardiac sympathetic nerve activity (CSNA) and baroreflex control of CSNA and heart rate in ovine pacing-induced HF. The resting level of CSNA was significantly higher in the HF than in the normal group, but the resting level of RSNA was unchanged. Intracerebroventricular infusion of the NO donor sodium nitroprusside (SNP; 500 μg · ml(-1)· h(-1)) in conscious normal sheep and sheep in HF inhibited CSNA and restored baroreflex control of heart rate, but there was no change in RSNA. Microinjection of SNP into the PVN did not cause a similar cardiac sympathoinhibition in either group, although the number of nNOS-positive cells was decreased in the PVN of sheep in HF. Reduction of endogenous NO with intracerebroventricular infusion of N(ω)-nitro-l-arginine methyl ester decreased CSNA in normal but not in HF sheep and caused no change in RSNA in either group. These findings indicate that endogenous NO in the brain provides tonic excitatory drive to increase resting CSNA in the normal state, but not in HF. In contrast, exogenously administered NO inhibited CSNA in both the normal and HF groups via an action on sites other than the PVN.
Real-Time Continuous Glucose Monitoring Together with Telemedical Assistance Improves Glycemic Control and Glucose Stability in Pump-Treated Patients (2008)

Real-time CGM in conjunction with the DIABTel system improves glycemic control and glucose stability in pump-treated patients with type 1 diabetes.
Current Awareness and Use of the Strain Echocardiography in Routine Clinical Practices: Result of a Nationwide Survey in Korea (2017)

Most of our study participants were aware of strain echocardiography, and all institutions performed strain echocardiography for clinical and research purposes. However, they did not think the LV strain values could replace LVEF. The diversity of strain measurements and lack of normal reference values were common reasons for not using strain echocardiography in clinical practice.
Predicting IDH mutation status in grade II gliomas using amide proton transfer‐weighted (APTw) MRI (2017)

IDH-wildtype lesions typically were associated with relatively high APTw signal intensities as compared with IDH-mutant lesions. The APTw signal could be a valuable imaging biomarker by which to identify IDH1 mutation status in grade II gliomas. Magn Reson Med 78:1100-1109, 2017. © 2017 International Society for Magnetic Resonance in Medicine.
Does the transapical approach impair early recovery of systolic strain following transcatheter aortic valve replacement? (2015)

Equal improvement in myocardial strain was observed in the TF and TA patients. Pre-TAVR GLS impairment was an independent predictor of post-TAVR GLS recovery, highlighting how it is the patient's baseline GLS dysfunction, not the method of approach, that dictates post-TAVR functional recovery.