gebhart/patrepeval huggingface dataset:
Development of a multi-source solar simulator for spatial uniformity and close spectral matching to AM0 and AM1.5 (2011)

Results from ongoing development of spatial and spectral quality of RIT's dual source solar simulator are presented. This simulator as designed qualifies as class A for both AM0 and AM1.5, depending on the filter set used. Measurements were made of spatial intensity uniformity, as well as spectral uniformity across the 300 mm diameter beam under calibrated AM0 conditions. The beam exhibits intensity non-uniformity across the 300 mm diameter test plane of 5.89%, though typically cells can be measured in a 10 cm × 10 cm central region of 1.13% non-uniformity. Spectral match and spectral mismatch values were calculated for specific spectral regions and device structures, respectively, which verified a close match to both AM0 and AM1.5G, especially in the region most commonly used for triple junction solar cells. Results of a set of ten Emcore BTJs measured at Emcore, Aerospace Corporation, NASA Glenn Research Center, and RIT, were compared. It was found that RIT's simulator produced figures of merit such as V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">OC</sub> , I <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">SC</sub> , fill factor, and efficiency, for these cells to within 2% of the other facilities.
Development of an advanced Two-Micron triple-pulse IPDA lidar for carbon dioxide and water vapor measurements (2018)

An advanced airborne triple-pulse 2-μm integrated path differential absorption (IPDA) lidar is under development at NASA Langley Research Center that targets both carbon dioxide (CO 2 ) and water vapor (H 2 O) measurements simultaneously and independently. This lidar is an upgrade to the successfully demonstrated CO 2 2-μm double-pulse IPDA. Upgrades include high-energy, highrepetition rate 2-μm triple-pulse laser transmitter, innovative wavelength control and advanced HgCdTe (MCT) electron-initiated avalanche photodiode detection system. Ground testing and airborne validation plans are presented.
Supplementary Tables and References from <i>BRCA2</i> Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer (2023)

&lt;p&gt;Table S1: Description of the BCAC studies contributing to COGS. Table S2: Predicted effects of BRCA1 and BRCA2 variants included in the iCOGS array on protein function. Table S3: Frequency of BRCA1 and BRCA2 variants from iCOGS in breast cancer cases and controls. Table S4: Family studies of Y3035S showing scores for each family by constant relative risk and 75% penetrance. Supplementary References.&lt;/p&gt;
How to Obtain and Analyze Electrocardiograms in Clinical Trials (1999)

Prolongation of the QT c interval on the ECG associated with reports of sudden death produced by noncardiac drugs has focused the attention of regulatory authorities on ECG findings from clinical drug development programs. During clinical testing, the nonrigorous, site‐specific, and largely uncontrolled methods for performing and analyzing ECGs that is currently practiced should now be reconsidered. Current methods may miss important cardiac electrophysiological effects of new drugs as well as produce false‐positive ECG findings that are artifactual and the result of the methods used. The use of a core ECG laboratory that has cardiovascular expertise, state‐of‐the‐art information management technologies, and ECG reading systems that are scientifically validated, quality assured, and precise can cost effectively manage a development program's entire ECG safety program. A.N.E. 1999;4(4):425–433
Dual-band integrated self-biased edge-mode isolator based on the double ferromagnetic resonance of a bistable nanowire substrate (2010)

A dual-band integrated self-biased edge-mode isolator based on the double ferromagnetic resonance of a CoFeB ferromagnetic nanowire (FMNW) substrate, controllable by the geometrical and composition parameters of the FMNWs, is presented. The dispersion diagram of the FMNW edge-mode isolator, taking into account the effective permittivity and permeability of the FMNW medium, predicts two frequency bands of operation. These bands are demonstrated experimentally using FMNWs of 40 nm diameter with a lattice constant of 110 nm. In the presented prototype, isolations of 17 dB at 27.3 GHz and 4.4 dB at 31.2 GHz are observed under zero external applied field. The isolation of the second frequency band is increased to 18.3 dB by applying a small DC magnetic field of 0.13 T. The integrability, self-biased, double resonance, millimeter-wave and dispersion engineering properties of the FMNW medium opens up new possibilities for a diversity of magnetic devices and systems.
PrevMap:R package (2015)

It provides functions for both likelihood-based and Bayesian analysis of spatially referenced prevalence data, and is also an extension of the 'geoR' package.
Ultra-wideband and high-gain parametric amplification in telecom wavelengths with an optimally mode-matched PPLN waveguide (2018)

We report a wideband optical parametric amplification (OPA) over 14 THz covering telecom S, C, and L bands with observed maximum parametric gain of 38.3 dB. The OPA is realized through cascaded second-harmonic generation and difference-frequency generation (cSHG-DFG) in a 2 cm periodically poled LiNbO<sub>3</sub> (PPLN) waveguide. With tailored cross section geometry, the waveguide is optimally mode matched for efficient cascaded nonlinear wave mixing. We also identify and study the effect of competing nonlinear processes in this cSHG-DFG configuration.
Thérapie cellulaire de la dystrophie musculaire de Duchenne: essai préclinique chez le chien myopathe (2011)

La dystrophie musculaire de Duchenne (DMD) est une maladie génétique progressive du muscle liée au chromosome X. Elle est la maladie génétique la plus fréquente chez l’homme. La thérapie cellulaire basée sur l’utilisation de cellules souches somatiques est une voie thérapeutique riche d’intérêt. Nous avons isolé, chez un modèle de chien myopathe, une cellule souche musculaire (MuStem) qui présente les qualités indispensables à une utilisation thérapeutique : forte capacité d’amplification, capacité à fusionner avec les fibres musculaires, renouvellement du contingent de cellules satellites, dispersion dans l’organisme après administration vasculaire, persistance de l’effet à long terme, spectaculaire amélioration clinique des animaux traités. Ces résultats précliniques ouvrent la voie à un essai thérapeutique chez l’enfant atteint de dystrophie musculaire de Duchenne.
[The EEG in anesthesia and intensive care monitoring]. (1984)

Electroencephalographic monitoring during anaesthesia and during intensive therapy has definite advantages. It aids the individual regulation and assessment of general anaesthesiological measures, and signals cerebral insufficiency in the patient under treatment. Examples illustrating initial cerebral states and characteristic changes of cerebral function related to anaesthesia in general, to various forms of anaesthesia as well as to the depth of anaesthesia, are presented. Other examples illustrate the significance of this method in interpreting the actual state of cerebral function during the course of intensive treatment. Possibilities of performing electroencephalographic registration during routine anaesthesiological procedures are discussed.
ChemInform Abstract: Aminopropyl Silica Gel Supported Iodine as Catalyst in Nucleophilic Ring Opening of Epoxides and Episulfides. (2002)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Investigations on Defect Equilibrium, Thermodynamic Quantities, and Transport Properties of La0.5Sr0.5FeO3-δ (2019)

In this work, relationship between defect equilibrium and thermodynamic quantities is investigated to elucidate mass and charge transport properties of La0.5Sr0.5FeO3-δ (LSF55). The oxygen nonstoichiometry (δ) was measured as a function of oxygen partial pressure in 10−19 ≤ ≤ 0.21 and 750 ≤ (T/°C) ≤ 900 range. The relationships indicated an electronic n-p transition point at δ = 0.25 which moved to a higher value with increasing temperature. The relative partial molar enthalpy () and entropy () of oxygen indicated that across the electronic stoichiometric point stabilized around −86.9 ± 3.6 kJ/mol in p-type and −402.2 ± 12.6 kJ/mol in n-type regimes, whereas values were kept changing because of the contribution from configuration entropy (SO(Conf)). From the DC 4-probe conductivity and electrical conductivity relaxation (ECR) measurement, the oxygen-ion conductivity at 900°C was 0.29 S.cm−1 with activation energy of 0.72 ± 0.04 eV and the oxygen self-diffusivity (DO) for LSF55 with δ = 0.114 during oxidation increased from (8.27 ± 0.05) × 10−8 cm2⋅s−1 at 800°C to (2.55 ± 0.01) × 10−7 cm2⋅s−1 at 900°C with an activation energy of 1.22 ± 0.14 eV. Dilatometry measurements indicated an isothermal chemical expansion as function of , which was explained on the basis of the relative change in mean ionic radius of transition metal cation Fe against δ. This model showed that transition metal cation existed as a mixture of high-spin and low-spin states and made a transition from low-spin to high-spin state with increasing δ.
Supplementary Table S1 from Mitotic Arrest, Apoptosis, and Sensitization to Chemotherapy of Melanomas by Methionine Deprivation Stress (2023)

Supplementary Table S1 from Mitotic Arrest, Apoptosis, and Sensitization to Chemotherapy of Melanomas by Methionine Deprivation Stress
Symposium Commemorating the Centenary of Medical Entomology, held at the Headquarters of the Royal Society of Tropical Medicine and Hygiene, Keppel Street, London, England, 23–25 November 1977 (1978)

Symposium Commemorating the Centenary of Medical Entomology, held at the Headquarters of the Royal Society of Tropical Medicine and Hygiene, Keppel Street, London, England, 23–25 November 1977 - Volume 5 Issue 2
Stress hysteresis and mechanical properties of plasma-enhanced chemical vapor deposited dielectric films (2004)

A comprehensive survey is described of the responses of three plasma-enhanced chemical vapor deposited dielectric film systems to thermal cycling and indentation contact. All three films—silicon oxide, silicon nitride, and silicon oxy-nitride—exhibited significant nonequilibrium permanent changes in film stress on thermal cycling or annealing. The linear relationship between stress and temperature changed after the films were annealed at 300 °C, representing a structural alteration in the film reflecting a change in coefficient of thermal expansion or biaxial modulus. A double-substrate method was used to deduce both thermoelastic properties before and after the anneal of selected films and the results were compared with the modulus deconvoluted from small-scale depth-sensing indentation experiments (nanoindentation). Rutherford backscattering spectrometry and hydrogen forward scattering were used to deduce the composition of the films and it was found that all the films contained significant amounts of hydrogen.
KVOPO<sub>4</sub> cathode for sodium ion batteries (2023)

An electrode comprising: NaVOPO&lt;sub&gt;4&lt;/sub&gt; having orthorhombic crystalline symmetry and space group Pna2&lt;sub&gt;1&lt;/sub&gt;, as an active intercalation host material, wherein the electrode is capable of electrochemical insertion and release of greater than one sodium ion per vanadium, wherein the NaVOPO&lt;sub&gt;4&lt;/sub&gt; is formed by a solid phase synthesis process from a heated powdered mixture of ammonium metavanadate, ammonium phosphate monobasic, and potassium carbonate, to yield NaVOPO&lt;sub&gt;4&lt;/sub&gt; having corner-sharing VO&lt;sub&gt;6&lt;/sub&gt; octahedra and PO&lt;sub&gt;4&lt;/sub&gt; tetrahedra, defining two types of tunnels comprising a first type of tunnel formed of rings of two PO&lt;sub&gt;4&lt;/sub&gt; tetrahedra and a second type of tunnel formed of rings of three PO&lt;sub&gt;4&lt;/sub&gt; tetrahedra and three VO&lt;sub&gt;6&lt;/sub&gt; octahedra, followed by substitution of the potassium ions with sodium ions.
[Keratinocyte-fibroblast interactions: I. Production by the keratinocytes of soluble factors stimulating the proliferation of normal human skin fibroblasts]. (1989)

Epidermal cells produce IL-1 and contra IL-1 which respectively stimulate and decrease fibroblast proliferation. In order to get better insight into the nature of keratinocyte-fibroblast interactions, we have analyzed the effect of soluble factors produced by unstimulated normal human keratinocytes and keratinocyte cell lines on the proliferation of normal human dermal fibroblasts. The results were compared to these obtained with human recombinant IL-1 and IL-2. We observed that: 1) normal keratinocytes (monolayers or stratified) released in the culture medium a factor stimulating fibroblast proliferation by 45 to 160%; 2) supernatants of unstimulated PAM 212 keratinocyte cell line also contained the stimulatory activity; 3) addition of IL-1 beta to the culture medium at concentration ranging from 0.1 to 1.000 U/ml induced a dose-dependent increase in fibroblast proliferation, whereas IL-2 was ineffective; 4) gel filtration analysis (ACA 54) of serum-free supernatant showed that the activity could be eluted from 3 peaks (Mw ranging from 10 to 20 kD). The present data show that unstimulated normal human keratinocytes produce soluble factor(s) (maybe related to IL-1) which stimulate human dermal fibroblast proliferation and which could be of major importance in the modulation of fibroblast metabolism, in vivo.
Inhibition of Topoisomerase I by Anti-Cancer Drug Altered the Endometrial Cyclicity and Receptivity (2014)

Topoisomerase I (topo I) is an essential nuclear enzyme involved in virtually all aspects of gene expression, and is the target of the anti-cancer drugs- camptothecin (CPT) and its derivatives. Improvement of the survival rates of young women with cancer has led to the consideration of the effects of long-term chemotherapy on their fertility. The effect of anticancer drugs on ovarian function was previously investigated; however, no reports are available concerning their effect on the endometrium, whose integrity is an important factor in embryo implantation. Here we used a rat animal model to investigate the expression and activity of topo I in the various physiologic phases of the endometrium and the influence of CPT on its integrity and receptivity. The results show, for the first time, that the endometrial topo I level and activity are influenced by the physiologic phases of the endometrium (estrous cycle) and correlate with the estrogen blood concentration. Treatment with the anti-cancer drug CPT caused histological disruption of the endometrium and deleterious effect on its cyclicity. Moreover, CPT treatment significantly reduced the implantation rate of embryos, suggesting alteration in the receptivity of the endometrium. These results suggest that topo I is important for maintaining the normal physiologic cyclicity and functionality of the endometrium in rats. Anti-cancer agents that target topo I severely impair estrous cycle progression and endometrial integrity and receptivity, emphasizing the importance of addressing the effect of chemotherapy on the endometrial functionality.
Investigation of Factors Affecting Early Quality of Life of Patients after Breast Cancer Surgery (2021)

The early QOL of postoperative patients with breast cancer is affected by multiple factors, such as upper limb function and postoperative chemotherapy, and thus comprehensive intervention is required.
Transcriptional activation of cyclin D1 via HER2/HER3 contributes to cell survival and EGFR tyrosine kinase inhibitor resistance in non-small cell lung carcinoma (2019)

Abstract Several different mechanisms are implicated in the resistance of lung cancer cells to epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs), and only few have been functionally investigated. Here, using genetically knocked out EGFR and TKI-resistant lung cancer cells, we show that loss of wild-type EGFR attenuates cell proliferation, migration and 3D-spherid formation, whereas loss of mutant EGFR or resistance to TKIs reinforces those processes. Consistently, disruption of wild-type EGFR leads to suppression of HER2/HER3, while mutant EGFR ablation or resistance to TKIs increases HER2/HER3 expression, compensating for EGFR loss. Furthermore, HER2/HER3 nuclear translocation mediates overexpression of cyclin D1, leading to tumor cell survival and drug resistance. Cyclin D1/CDK4/6 inhibition resensitizes erlotinib-resistant (ER) cells to erlotinib. Analysis of cyclin D1 expression in patients with non-small cell lung carcinoma (NSCLC) showed that its expression is negatively associated with overall survival and disease-free survival. Our results provide biological and mechanistic insights into targeting EGFR and TKI resistance.
Study of the pattern of Widal test in infants and children. I. Pattern of Widal test among apparently normal infants and children. (1975)

690 apparently normal infants and children from Assiut-Upper Egypt--were submitted to Widal test. They were 0-15 years old, of both sexes (382 males and 308 females) and from both the urban and rural localities (433 and 257 respectively). --The frequency of single agglutinin titers is discussed. --The dual Widal titer combining "O" agglutinin in a titer of 1/40 or more with "H" agglutinin 1/80 or more, was fulfilled by 252 (36.5%) :-- A--106 (15.3%) showed a simultaneous rise of T."H", paratyphi A "H" and paratyphi B "H" agglutinins suggesting an effect of recent previous T.A.B. vaccination. B--146 persons (21.1%), showed a rise of only one or two "H" agglutinins, probably an effect of natural exposure to enteric fever agents reflecting the endemicity of infection. Further study of this group revealed: 1--There is a past experience with a single enteric fever agent in 63 persons (9.1%) with the following order of frequency : S.typhi (5.2%), S. paratyphi A (2.9%) and S. Paratyphi B. (1.01%). 2--The distribution of the group with rise of only one or two "H" agglutinins, by age, sex and locality is discussed. Apparently there is an initial high rate in the first year of life that declines in the age group 1--5 years to increase in the age group 6--9 years and the older age groups.
Free amalgams of rank two (1995)

For every <inline-formula content-type="math/mathml"> <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" alttext="n greater-than 1"> <mml:semantics> <mml:mrow> <mml:mi>n</mml:mi> <mml:mo>&gt;</mml:mo> <mml:mn>1</mml:mn> </mml:mrow> <mml:annotation encoding="application/x-tex">n &gt; 1</mml:annotation> </mml:semantics> </mml:math> </inline-formula> and <inline-formula content-type="math/mathml"> <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" alttext="m greater-than 1"> <mml:semantics> <mml:mrow> <mml:mi>m</mml:mi> <mml:mo>&gt;</mml:mo> <mml:mn>1</mml:mn> </mml:mrow> <mml:annotation encoding="application/x-tex">m &gt; 1</mml:annotation> </mml:semantics> </mml:math> </inline-formula> we construct an amalgamated free product <inline-formula content-type="math/mathml"> <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" alttext="upper U asterisk Subscript upper W Baseline upper V"> <mml:semantics> <mml:mrow> <mml:mi>U</mml:mi> <mml:mrow class="MJX-TeXAtom-ORD"> <mml:msub> <mml:mo>∗</mml:mo> <mml:mi>W</mml:mi> </mml:msub> </mml:mrow> <mml:mi>V</mml:mi> </mml:mrow> <mml:annotation encoding="application/x-tex">U{ \ast _W}V</mml:annotation> </mml:semantics> </mml:math> </inline-formula> which is free of rank 2, while <italic>U</italic> is (free) of rank <italic>n , V</italic> is of rank <italic>m</italic>, and <italic>W</italic> is, necessarily, of rank <inline-formula content-type="math/mathml"> <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" alttext="n plus m minus 2"> <mml:semantics> <mml:mrow> <mml:mi>n</mml:mi> <mml:mo>+</mml:mo> <mml:mi>m</mml:mi> <mml:mo>−</mml:mo> <mml:mn>2</mml:mn> </mml:mrow> <mml:annotation encoding="application/x-tex">n + m - 2</mml:annotation> </mml:semantics> </mml:math> </inline-formula>.
Iron Metabolism Regulates p53 Signaling through Direct Heme-p53 Interaction and Modulation of p53 Localization, Stability, and Function (2014)

Iron excess is closely associated with tumorigenesis in multiple types of human cancers, with underlying mechanisms yet unclear. Recently, iron deprivation has emerged as a major strategy for chemotherapy, but it exerts tumor suppression only on select human malignancies. Here, we report that the tumor suppressor protein p53 is downregulated during iron excess. Strikingly, the iron polyporphyrin heme binds to p53 protein, interferes with p53-DNA interactions, and triggers both nuclear export and cytosolic degradation of p53. Moreover, in a tumorigenicity assay, iron deprivation suppressed wild-type p53-dependent tumor growth, suggesting that upregulation of wild-type p53 signaling underlies the selective efficacy of iron deprivation. Our findings thus identify a direct link between iron/heme homeostasis and the regulation of p53 signaling, which not only provides mechanistic insights into iron-excess-associated tumorigenesis but may also help predict and improve outcomes in iron-deprivation-based chemotherapy.
Design and implementation of data management subsystem in Environmental Sensor Networks (2012)

“Environmental Sensor Networks (ESNs)” are a subset of sensor networks which are specifically tuned to an environmental application. In general, there are three main subsystems in the whole infrastructure of ESNs: (1) Data acquisition subsystem; (2) Data communication subsystem; (3) Data management subsystem. Compared with two former ones, the research on data management subsystem has not been attached more importance. However, with the number of diverse sensors is increasing, integrating, sharing and visualizing the monitored data among the isolated sensor networks has become a critical problem. Thus, this paper introduces the design and implementation of data management subsystem in ESNs. The design is based on SOA (Service Oriented Architecture), for the monitored data is distributed, multiple sourced, and heterogeneous. RIA (Rich Internet Application) is the main developing mode to implement the data management subsystem. If it is combined with the whole infrastructure of ESNs efficiently, the data management subsystem can obtain more information directly, and visualize them more quickly.