gebhart/patrepeval huggingface dataset:
Comparative morphometric analysis of nuclear area and shape in peripheral T-zone lymphomas and in paracortical areas of normal and reactive lymph nodes. (1988)

The areas and shapes of cell nuclei were morphometrically analyzed in peripheral T-zone lymphomas, which have a characteristic nuclear pleomorphism, as well as in paracortical areas of normal and reactive lymph nodes; the aim of the study was to compare the neoplastic and nonneoplastic lymphoid cell populations. Although the means and standard deviations (SDs) of nuclear area and shape features differed significantly between the T-zone lymphomas, reactive nodes and normal nodes, there was considerable overlap between the lymphomas and the reactive lymph nodes in all of the features investigated. Therefore, the composition of populations of nuclei was studied. In lymphomas, the frequencies of regular and irregular nuclei were about the same in all nuclear area classes, whereas increasingly larger nuclei had an increasingly regular shape in reactive lymph nodes. An attempt to classify the cells, divided into those with small nuclei (less than 25 sq microns) and those with large nuclei (greater than 25 sq microns), on the basis of their morphometric shape features showed the usefulness of form factors in the class of nuclei with a large area. The results show that, while means and SDs of nuclear area and shape are not very accurate descriptors of the differences between the T-zone lymphomas and nonneoplastic lymph nodes, analysis of the percentage of regularly shaped nuclei in a certain nuclear area class can describe the differences much more accurately. The compositional differences in nuclear shape are in agreement with subjective impressions and can objectively support the pathologist's qualitative impression of pleomorphism in malignant T-zone lymphomas.
Superresolution techniques and ISAR imaging (2003)

High-resolution optimal estimation techniques are applied to the problem of radar imaging of rotating objects, sometimes referred to as ISAR (inverse synthetic array radar) imaging. Typical digital range-Doppler processing operations are described, utilizing two spectral estimation techniques. Quality ISAR images have been obtained from such processing, and particular examples, which are based on simulated data generated from point-target models of rotating objects, are shown. The first example is a so-called merry-go-round of 24 point-targets, and the MLM (maximum-likelihood method) algorithm is utilized to process a 3-D range-Doppler image estimate. The second example is a rotating boom along which are located 15 point-targets including a doublet, a triplet, and a quadruplet cluster that require superresolution techniques to resolve in the Doppler domain. It is concluded that superresolution techniques offer a viable alternative to conventional DFT (discrete Fourier transform) ISAR image processing and should permit either higher resolution images from the same data samples or equal-quality images from significantly fewer data samples.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Influence of PAMAM dendrimers on the human insulin (2015)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Olga Nowacka, Katarzyna Miłowska, Maksim Ionov, Maria Bryszewska; Influence of PAMAM dendrimers on the human insulin. AIP Conference Proceedings 17 December 2015; 1695 (1): 020028. https://doi.org/10.1063/1.4937306 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
Photocontrolled Release of Carbendazim from Photocaged Molecule (2023)

Carbendazim (MBC) is a high-efficient and broad-spectrum fungicide, but excessive residues caused by its improper use have caused health toxicity and environmental pollution. It is an irresistible trend to find green, safe, accurate and controllable release technology of MBC. To achieve the purpose of safe and efficient use of MBC, photolabile protecting group was used to realize the controllable release. This study aimed to covalently link MBC and 6-nitropiperonyl alcohol (NP) to synthesize photocaged molecule NP-MBC. The photodegradation test showed that NP-MBC could effectively release MBC under ultraviolet light. The antifungal activity of NP-MBC showed significant difference against Rhizoctonia solani, Sclerotinia sclerotiorum and Fusarium graminearum before and after irradiation, and the effects on mycelial morphology are different. The hyphae morphology of R. solani and F. graminearum changed significantly, and mycelia were severely damaged. The hyphae surface of former was swollen and broken, and the latter was collapsed and shriveled after NP-MBC light treatment. NP-MBC could realize the light-controlled release of MBC, and the antifungal activity before and after irradiation was significantly different, which provides an effective way to release MBC.
CoAST (2014)

The explosive growth of mobile data traffic poses severe pressure on cellular providers to better manage their finite spectrum. Proposed solutions such as congestion-pricing exist, but they degrade users' ability to use the network when they want. In this paper, we propose a fundamentally different approach - rather than reducing the aggregate busy hour traffic, we seek to smooth the peaks that cause congestion. Our approach is based on two key insights obtained from traffic traces of a large cellular provider. First, mobile traffic demonstrates high short-term variation so that delaying traffic for very short periods of time can significantly reduce peaks. Second, by making collaborative decisions on which traffic gets delayed and by how much across all users of a cell, the delays need not result in any degradation of user experience. We design a system, CoAST, to implement this approach using three key mechanisms: a protocol to allow mobile applications and providers to exchange traffic information, an incentive mechanism to incentivize mobile applications to collaboratively delay traffic at the right time, and mechanisms to delay application traffic. We provide extensive evaluations that show that CoAST reduces traffic peaks by up to 50% even for applications that are not thought to be delay-tolerant, e.g., streaming and web browsing, but which together account for 70% of all cellular traffic.
Highly efficient, general hydrogenation of aldehydes catalyzed by PNP iron pincer complexes (2014)

Well-defined iron pincer complexes are effective catalysts for the synthetically and industrially important hydrogenation of aldehydes to alcohols.
Do You Talk to Each Poster? Security and Privacy for Interactions with Web Service by Means of Contact Free Tag Readings (2009)

The pervasive service interaction (PERCI) application allows interaction with Web services through associated real world objects equipped with contact less tags. The tags are read with a mobile. The read tag content is used to invoke Web service in the back-end system. The case study presented here is identifying in a structured approach security and privacy requirements of an near field communication (NFC) based application. As the application is leaving the technology research stage and is about to enter some system development stage it was indicated to consider security and privacy for R&D risk management purposes. The application is representative for a service, deployable on a mobile using NFC technology and building on Web services taking particularly the stake-holder role-specific situations and the operation of the application as a telecommunication service into account. The contributions of the paper relate to (i) the security discussion that avoids threats where this is possible and mitigates the remaining risks where this is necessary and (ii) the way to structure and organize the different aspects of the security and privacy consideration, which can be applied elsewhere too.
Hepatic arterial infusion chemotherapy and sorafenib for the treatment of advanced hepatocellular carcinoma patients (2014)

Sorafenib has been established as a standard therapy to prolong survival in patients with advanced hepatocellular carcinoma patients when locoregional therapy is not indicated; however the benefit of hepatic arterial infusion chemotherapy (HAIC) as an alternative option remains controversial. Although further research to optimize the use of HAIC and sorafenib is ongoing, we present an overview of the factors influencing the management of long-term survival following sorafenib or HAIC treatment.
Wave front reversal with frequency conversion in a nonreciprocal medium (2006)

The phenomenon of wave front reversal in a nonreciprocal medium has been discovered and studied experimentally. The phenomenon has been investigated on the example of parametric wave front reversal of nonreciprocal surface spin waves in a ferrite film with asymmetric surface metallization. It was found that the carrier frequency of the reversed wave packet is not equal to the carrier frequency of the incoming wave packet, and the magnitude of this frequency difference increases linearly with the decrease of the bias magnetic field. The discovered effect can be used for manipulation of pulsed signals in a microwave frequency range.
Operation of a seeded XUV free-electron laser at DESY with high-gain harmonic generation (2017)

The XUV free electron laser FLASH, has been recently operated in the high-gain harmonic generation (HGHG) mode. We characterized the laser-induced energy modulation, as well as the temporal profile of the seeded FEL pulses. FEL saturation was reached for the 7th harmonic of the 266 nm seed laser.
Silicon-film{sup {trademark}} photovoltaic manufacturing technology. Final technical status report, January 1, 1992--July 31, 1995 (1996)

The goal of AstroPower's PVMaT-2A project was to develop an advanced, low-cost manufacturing process for a new utility-scale, flat-plate module. This process starts with the production of continuous sheets of polycrystalline silicon on a supporting substrate using the Silicon-Film{trademark} process. A number of new solar cell and module products have resulted from this work. The primary product is a 240 cm{sup 2} solar cell referred to as the AP-225. This product has achieved an efficiency of 12.2% (AM1.5G, 1000 W/m{sup 2}). A 17.1kW array was constructed for PVUSA using the AP-225 solar cell and was installed in November 1994. Along with the AP-225, a second, larger, solar cell was developed. The AP-675 solar cell has a device area of 700 cm{sup 2} and has achieved an efficiency of 11.6% (AM1.5G, 1000 W/m{sup 2}). Two new module products accompanied the new solar cell products. Table 1 shows the details of the products developed in this program.
Learned Dynamics of Reaching Movements Generalize From Dominant to Nondominant Arm (2003)

Accurate performance of reaching movements depends on adaptable neural circuitry that learns to predict forces and compensate for limb dynamics. In earlier experiments, we quantified generalization from training at one arm position to another position. The generalization patterns suggested that neural elements learning to predict forces coded a limb's state in an intrinsic, muscle-like coordinate system. Here, we test the sensitivity of these elements to the other arm by quantifying inter-arm generalization. We considered two possible coordinate systems: an intrinsic (joint) representation should generalize with mirror symmetry reflecting the joint's symmetry and an extrinsic representation should preserve the task's structure in extrinsic coordinates. Both coordinate systems of generalization were compared with a naïve control group. We tested transfer in right-handed subjects both from dominant to nondominant arm (D-->ND) and vice versa (ND-->D). This led to a 2 x 3 experimental design matrix: transfer direction (D-->ND/ND-->D) by coordinate system (extrinsic, intrinsic, control). Generalization occurred only from dominant to nondominant arm and only in extrinsic coordinates. To assess the dependence of generalization on callosal inter-hemispheric communication, we tested commissurotomy patient JW. JW showed generalization from dominant to nondominant arm in extrinsic coordinates. The results suggest that when the dominant right arm is used in learning dynamics, the information could be represented in the left hemisphere with neural elements tuned to both the right arm and the left arm. In contrast, learning with the nondominant arm seems to rely on the elements in the nondominant hemisphere tuned only to movements of that arm.
Linear thermoacoustic instability in the time domain (1998)

An approximate time-domain description of the development of the thermoacoustic instability in gas-filled tubes is developed by exploiting the difference between the instability time scale and the period of standing waves. The perturbation results compare very favorably with the exact frequency-domain theory of Rott. The perturbation results are further simplified by introducing a short-stack approximation which is numerically much simpler and only slightly less accurate. An approximate expression for the critical temperature gradient accounting for viscous effects and other design features is also derived. In addition to the fundamental mode of a tube closed at both ends, the theory includes higher modes as well as open-end boundary conditions.
Data Storage Networking: Real World Skills for the CompTIA Storage+ Certification and Beyond (2014)

Learn efficient ways to harness and manage your data storage networks Whether you're preparing for the CompTIA Storage+ exam or simply seeking a deeper understanding of data storage networks, this Sybex guide will help you get there. This book covers data storage from the basics to advanced topics, and provides practical examples to show you ways to deliver world-class solutions. In addition, it covers all the objectives of the CompTIA Storage+ exam (SG0-001), including storage components, connectivity, storage management, data protection, and storage performance. Focuses on designing, implementing, and administering storage for today's evolving organizations, getting under the hood of the technologies that enable performance, resiliency, availability, recoverability, and simplicity Covers virtualization, big data, cloud storage, security, and scalability as well as how storage fits in to the wider technology environments prevalent in today's cloud era Provides advice and real-world examples that storage administrators in the trenches can actually use An excellent study aid for the CompTIA Storage+ exam (SG0-001), covering all the exam objectives Data Storage Networking: Real World Skills for the CompTIA Storage+ Certification and Beyond provides a solid foundation for data storage administrators and a reference that can be consulted again and again.
Simple Synthesis of Two Naphthoquinone Antibiotics Psychorubrin and Pentalongin. (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
A Survey of Advanced Methods for Analysis and Modeling of Propulsion System Reliability (2007)

Electronic controls, propulsion system monitoring and health management and application of information technology to maintenance data capture and storage are enabling users to accumulate large amounts of reliability and related maintenance data. Effective analysis and exploitation of these data bases requires advanced tools to extract meaningful and actionable information. The challenges include “competing” failure modes and periodic hard time maintenance that “censors” information from impending failures, and a high number of failure modes that confound analysis. These factors impede accurate assessment of the impact of corrective action and different maintenance procedures on availability and maintenance costs. They confound understanding of the reliability of complex propulsion &amp; power systems that would enable more representative modeling of system availability and maintenance costs for both existing and future applications. Tools providing more complete and accurate characterization of reliability information for complex systems are being developed for aerospace, nuclear and communications industries. These are surveyed and capability gaps identified with respect to commercial and military propulsion &amp; power systems.
FORMATION OF BILAYER SHALLOW MOSI2/COSI2 SALICIDE CONTACT USING W/CO-MO ALLOY METALLIZATION (1992)

A very simple process to form a bilayer shallow MoSi2/CoSi2/Si silicided contact using W/Co54Mo46/Si bilayer alloy metallization has been developed. Two-step annealing in a conventional flowing-nitrogen furnace is employed. The first annealing is performed at a temperature of 500-600°C, with the W film passivating the underlying Co-Mo alloy layer from being oxidized and consuming some Co. A shallow contact is feasible by selectively etching away the remaining outer layer of the Mo-dominant Mo-Co alloy (or W-Co alloy) phase to deduct the metal source which would finally be transformed into silicides. Silicide lateral growth which is observed during the silicidation of Co on Si does not occur in the present system. This is presumably because the formation of CoSi2 is not preceded by Co2Si or CoSi due to the nonrich Co source in the Co-Mo alloy system. The second annealing performed at a higher temperature of 700-950°C is to further transform the CoSi2 and mixed-silicide layers obtained after the first annealing into separate layers of MoSi2 and CoSi2.
A novel strategy for the synthesis in supercritical fluids of silicon particles for near-infrared and optical metamaterials (2019)

The synthesis of silicon micro- and nanoparticles is a central topic in the field of material chemistry. This material is particularly well suited for many different applications, from the realization of luminescent labels for in vitro and in vivo imaging 1 to the production of cathodes for lithium batteries 2. Recently, it has been reported that sub-micrometer Si particles are ideal for the production of optical and near-infrared metamaterials3. Today, the production of silicon particles is mainly addressed via soft chemistry routes, such as the reduction of silicon tetrachloride with strong reducing agents 4,5. These strategies typically yield low quantities of small silicon particles, and tedious post-synthesis purification steps are required to remove the by-products. These processes are not suitable for the continuous synthesis of Si particles in large quantities, and their scale-up from laboratory to industrial production is impaired. In this oral communication, we propose a novel strategy for the production of large silicon beads, using supercritical fluids. In this oral communication, we propose a novel strategy for the production of large silicon beads, using supercritical fluids.
Diagnosing root causes of intermittent slow queries in cloud databases (2020)

With the growing market of cloud databases, careful detection and elimination of slow queries are of great importance to service stability. Previous studies focus on optimizing the slow queries that result from internal reasons (e.g., poorly-written SQLs). In this work, we discover a different set of slow queries which might be more hazardous to database users than other slow queries. We name such queries Intermittent Slow Queries (iSQs), because they usually result from intermittent performance issues that are external (e.g., at database or machine levels). Diagnosing root causes of iSQs is a tough but very valuable task. This paper presents iSQUAD, Intermittent Slow QUery Anomaly Diagnoser, a framework that can diagnose the root causes of iSQs with a loose requirement for human intervention. Due to the complexity of this issue, a machine learning approach comes to light naturally to draw the interconnection between iSQs and root causes, but it faces challenges in terms of versatility, labeling overhead and interpretability. To tackle these challenges, we design four components, i.e., Anomaly Extraction, Dependency Cleansing, Type-Oriented Pattern Integration Clustering (TOPIC) and Bayesian Case Model. iSQUAD consists of an offline clustering &amp; explanation stage and an online root cause diagnosis &amp; update stage. DBAs need to label each iSQ cluster only once at the offline stage unless a new type of iSQs emerges at the online stage. Our evaluations on real-world datasets from Alibaba OLTP Database show that iSQUAD achieves an iSQ root cause diagnosis average F1-score of 80.4%, and outperforms existing diagnostic tools in terms of accuracy and efficiency.
DNA-Methylation-Caused Downregulation of miR-30 Contributes to the High Expression of XPO1 and the Aggressive Growth of Tumors in Pancreatic Ductal Adenocarcinoma (2019)

Pancreatic ductal adenocarcinoma is one of the most aggressive cancers, with high mortality in the United States. One of the important signal transduction proteins involved in the regulation of pancreatic cancer's aggressive progression is the nuclear export protein (XPO1). High expression of XPO1 has been found in pancreatic, lung, breast and other cancers and lymphomas with a poor prognosis of patients with tumors and high proliferative activity of cancer cells. Because XPO1 exports multiple tumor suppressor proteins simultaneously from the nucleus, the inhibition of XPO1 may retain multiple tumor suppressors in the nucleus, resulting in the suppression of cell proliferation and the induction of apoptosis in tumors. In this study, we found that the high expression of XPO1 in pancreatic cancer cells could be, in part, due to the methylation of the <i>miR-30</i> gene, leading to the low expression level of the <i>miR-30</i> family. By co-transfection of the XPO1 3'-UTR-Luc target vector with <i>miR-30</i> mimic, we found that XPO1 is a direct target of the <i>miR-30</i> family. We also observed that the enforced expression of the <i>miR-30</i> family inhibited the expression of XPO1, resulting in the suppression of pancreatic cancer growth both in vitro and in vivo. These findings could help to design a novel therapeutic strategy for the treatment of pancreatic cancer by introducing <i>miR-30</i> into cancer cells.
A Current Awareness Service Using Microcomputer Databases and Electronic Mail (1993)

Libraries are challenged economically to provide customized services to faculty and researchers who have ongoing needs for specialized information. This report describes a pilot currant awareness service which provided individual faculty with weekly searches of recently published literature, while incurring relatively low costs. Search results were generated using microcomputer databases and were transmitted electronically to faculty using a combination of mainframe computing, a high-speed campus network, and electronic mail. The methodology, which incorporated an automatic mailing program, is detailed. Costs are analyzed and projected for an expanded service to a moderately large faculty population
Charge Collection and Charge Sharing in a 130 nm CMOS Technology (2006)

Charge sharing between adjacent devices can lead to increased Single Event Upset (SEU) vulnerability. Key parameters affecting charge sharing are examined, and relative collected charge at the hit node and adjacent nodes are quantified. Results show that for a twin-well CMOS process, PMOS charge sharing can be effectively mitigated with the use of contacted guard-ring, whereas a combination of contacted guard-ring, nodal separation, and interdigitation is required to mitigate the NMOS charge sharing effect for the technology studied