gebhart/patrepeval huggingface dataset:
Phase-Based Non-Rigid 3D Image Registration - From Minutes to Seconds Using CUDA (2011)

Abstract. Image registration is a well-known concept within the medical image domain and has been shown to be useful in a number of different tasks. However, due to sometimes long processing times, image registration is not fully utilized in clinical workflows, where time is an important factor. During the last couple of years, a number of significant projects have been introduced to make the computational power of GPUs available to a wider audience, where the most well known is CUDA. In this paper we present, with the aid of CUDA, a speedup in the range of 38-44x (from 29 minutes to 40 seconds) when implementing a phasebased non-rigid image registration algorithm, known as the Morphon, on a single GPU. The achieved speedup is in the same magnitude as the speedups reported from other non-rigid registration algorithms fully ported to the GPU. Given the impressive speedups, both reported in this paper and other papers, we therefore consider that it is now feasible to effectively integrate image registration into various clinical workflows, where time is a critical factor. 1
Effects of several metals on spore, biomass, and geosmin production byStreptomyces tendae andPenicillium expansum (1996)

Cultures ofStreptomyces tendae andPenicillium expansum grown on Actinomyces and Czapek's media, respectively, were exposed to 5 mg L−1 of manganese, magnesium, iron, cobalt, nickel, copper and zinc, supplied as sulfate salts. Only copper markedly increased geosmin (1α, 10β-dimethyl-9α-decalol), biomass, and spore production. inductively coupled plasma-atomic emission spectrometric analysis ofS. tendae andP. expansum cells did not indicate an accumulation of copper. Both 1 and 5 mg L−1 copper, as copper sulfate, increased total geosmin production in cultures ofS. tendae on several media, but decreased production on others, suggesting that substrate composition affects responses to copper.
dc effects in elastic surface waves (1974)

We report the observation of dc effects in elastic surface waves on 131° rotated Y-cut X-propagating LiNbO3. A simple model to account for these effects is suggested.
Dexamethasone-Enhanced Continuous Online Microdialysis for Neuromonitoring of O2 after Brain Injury (2023)

Traumatic brain injury (TBI) is a major public health crisis in many regions of the world. Severe TBI may cause a primary brain lesion with a surrounding penumbra of tissue that is vulnerable to secondary injury. Secondary injury presents as progressive expansion of the lesion, possibly leading to severe disability, a persistent vegetive state, or death. Real time neuromonitoring to detect and monitor secondary injury is urgently needed. Dexamethasone-enhanced continuous online microdialysis (Dex-enhanced coMD) is an emerging paradigm for chronic neuromonitoring after brain injury. The present study employed Dex-enhanced coMD to monitor brain K<sup>+</sup> and O<sub>2</sub> during manually induced spreading depolarization in the cortex of anesthetized rats and after controlled cortical impact, a widely used rodent model of TBI, in behaving rats. Consistent with prior reports on glucose, O<sub>2</sub> exhibited a variety of responses to spreading depolarization and a prolonged, essentially permanent decline in the days after controlled cortical impact. These findings confirm that Dex-enhanced coMD delivers valuable information regarding the impact of spreading depolarization and controlled cortical impact on O<sub>2</sub> levels in the rat cortex.
Novel motor design for rotating anode x-ray tubes operating in the fringe field of a magnetic resonance imaging system (2013)

The proposed design can serve as a direct replacement to the conventional induction motor used in rotating anode x-ray tubes. It does not suffer from a reduced rotation speed when operating in a MR environment. The presence of chromic steel bearings in the prototype prevented testing at the higher field strengths, and future iterations of the design could eliminate this shortcoming. The prototype assembly demonstrates proof of concept of the authors' design and overcomes one of the major obstacles for a MR compatible rotating anode x-ray tube.
Improvement in PV Plant LCOE from Convection Heat Transfer Changes from Altered Plant Layout (2022)

Heat transfer modeling that accounts for how convective cooling changes with PV array layout has been found to improve system LCOE in certain climates conditions. Analysis of fixed tilt systems performed using the System Advisor Model reveals that reducing system ground coverage ratio from 0.46 to 0.35 can lead to as much as a 1.7% increase in module annual energy output in Phoenix. Depending on climate conditions, these energy increases due to changing convective cooling flow can lead to LCOE improvements for systems with increased row spacing despite the increased wiring and land costs associated with increased module row spacing. While the energy gain from decreasing system ground coverage ratio can be largely attributed to increased plane of array irradiance, the convection cooling considerations presented here can have a non-negligible impact on PV power plant energy output and economic viability depending on climate conditions and array spacing parameters.
ChemInform Abstract: Synthesis of Organic Phosphines and Phosphine Oxides from Elemental Phosphorus and Phosphine in the Presence of Strong Bases (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Cancellation accuracy in CDMA pilot interference cancellation (2004)

Pilot interference cancellation (IC) in mobile receivers has recently gained attention for CDMA cellular networks. In this paper we address the accuracy of the pilot interference cancellation at the receiver. In doing so, we consider the effects of channel estimation, timing estimation, receiver tap-spacing granularity, and the other receiver imperfections. The analytical and simulation results illustrate that high cancellation accuracy is feasible for the pilot IC receiver. These result indicate that the significant potential capacity gains reported in [3GPP TR 25.99, 2001, J.S. Sadowski et al., 2003] for pilot IC, are achievable under realistic receiver conditions.
The Antimalarial Activities of Methylene Blue and the 1,4-Naphthoquinone 3-[4-(Trifluoromethyl)Benzyl]-Menadione Are Not Due to Inhibition of the Mitochondrial Electron Transport Chain (2013)

Methylene blue and a series of recently developed 1,4-naphthoquinones, including 3-[4-(substituted)benzyl]-menadiones, are potent antimalarial agents in vitro and in vivo. The activity of these structurally diverse compounds against the human malaria parasite Plasmodium falciparum might involve their peculiar redox properties. According to the current theory, redox-active methylene blue and 3-[4-(trifluoromethyl)benzyl]-menadione are "subversive substrates." These agents are thought to shuttle electrons from reduced flavoproteins to acceptors such as hemoglobin-associated or free Fe(III)-protoporphyrin IX. The reduction of Fe(III)-protoporphyrin IX could subsequently prevent essential hemoglobin digestion and heme detoxification in the parasite. Alternatively, owing to their structures and redox properties, methylene blue and 1,4-naphthoquinones might also affect the mitochondrial electron transport chain. Here, we tested the latter hypothesis using an established system of transgenic P. falciparum cell lines and the antimalarial agents atovaquone and chloroquine as controls. In contrast to atovaquone, methylene blue and 3-[4-(trifluoromethyl)benzyl]-menadione do not inhibit the mitochondrial electron transport chain. A systematic comparison of the morphologies of drug-treated parasites furthermore suggests that the three drugs do not share a mechanism of action. Our findings support the idea that methylene blue and 3-[4-(trifluoromethyl)benzyl]-menadione exert their antimalarial activity as redox-active subversive substrates.
Autobiography of Alfons Baiker (2011)

ADVERTISEMENT RETURN TO ISSUEPREVSpecial Issue Prefac...Special Issue PrefaceNEXTAutobiography of Alfons BaikerAlfons BaikerView Author Information Cite this: J. Phys. Chem. C 2011, 115, 4, 842–845Publication Date (Web):January 27, 2011Publication History Published online27 January 2011Published inissue 3 February 2011https://pubs.acs.org/doi/10.1021/jp1079873https://doi.org/10.1021/jp1079873introductionACS PublicationsCopyright © 2011 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views538Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (36 KB) Get e-AlertscloseSUBJECTS:Catalysis,Catalytic reactions,Materials,Spectroscopy,X-ray absorption spectroscopy Get e-Alerts
Dietary BMAA Exposure in an Amyotrophic Lateral Sclerosis Cluster from Southern France (2013)

While it is not possible to ascertain a direct link between shellfish consumption and the existence of this ALS cluster, these results add new data to the potential association of BMAA with sporadic amyotrophic lateral sclerosis, one of the most severe neurodegenerative disorder.
Protein import into mitochondria: the requirement for external ATP is precursor-specific whereas intramitochondrial ATP is universally needed for translocation into the matrix. (1994)

ATP is needed for the import of precursor proteins into mitochondria. However, the role of ATP and its site of action have been unclear. We have now investigated the ATP requirements for protein import into the mitochondrial matrix. These experiments employed an in vitro system that allowed ATP levels to be manipulated both inside and outside the mitochondrial inner membrane. Our results indicate that there are two distinct ATP requirements for mitochondrial protein import. ATP in the matrix is always needed for complete import of precursor proteins into this compartment, even when the precursors are presented to mitochondria in an unfolded conformation. In contrast, the requirement for external ATP is precursor-specific; depletion of external ATP strongly inhibits import of some precursors but has little or no effect with other precursors. A requirement for external ATP can often be overcome by denaturing the precursor with urea. We suggest that external ATP promotes the release of precursors from cytosolic chaperones, whereas matrix ATP drives protein translocation across the inner membrane.
Analysis of Explosives and Explosive Residues. Part 3: Monomethylamine Nitrate (1975)

Abstract The E. I. du Pont de Nemours &amp; Co., Inc. has recently announced that it is discontinuing the manufacturing of nitroglycerin-based dynamites and is replacing them with formulations whose primary ingredients are ammonium nitrate (AN) and monomethylamine nitrate (MMAN). The forensic chemist is thus confronted with the need to be able to analyze residues for the possible use of this type of explosive.
Successful living donor intestinal transplantation in cross-match positive recipients: Initial experience (2016)

Sensitized patients tend to have longer waiting times on the deceased donor list and are at increased risk of graft loss from acute or chronic rejection compared to non-sensitized candidates. Desensitization protocols are utilized to decrease the levels of alloantibodies and to convert an initial positive cross-match to prospective donors into a negative crossmatch. These procedures are mostly available in the setting of living donation. Due to the elective nature of the procedure, desensitization protocols can be extended until the desire result is obtained prior to transplantation. We present two cases of successful desensitization protocol applied to living donor intestinal transplant candidates that converted to negative cross-match to their donors. We present two cases of intestinal transplant candidates with a potential living donor to whom they are sensitized. Both cases underwent successful transplantation after desensitization protocol. No evidence of humoral rejection has occurred in either recipient. Living donor intestinal transplantation in sensitized recipients against the prospective donors provides the ability to implement a desensitization protocol to convert to negative cross-match.
Defect and impurity engineered semiconductors and devices 2. Materials Research Society symposium proceedings Volume 510 (1998)

The evolution of semiconductor devices of progressively higher performance has generally followed improved material quality with ever fewer defect concentrations. However, a shift in focus over the past few years has brought the realization that complete elimination of defects in semiconductors during growth and processing is neither desirable nor necessary. In fact, it is expected that the future role of defects in semiconductors will be one of control--in density, properties, spatial location, and perhaps even temporal variation during the operating lifetime of the device. Both the academic and industrial research communities come together in this volume to explore the effective use of defect control at various facets of technology and widely different semiconductor materials systems. Topics include: grown-in defects in bulk crystals; doping issues; grown-in defects in thin films; doping and defect issues in wide-gap semiconductors; process-induced defects and gettering; defect properties, reactions, activation and passivation; ion implantation and irradiation effects; defects in devices and interfaces; plasma processing; defect characterization; and interfaces, quantum wells and superlattices.
Evaluation of the UCSF microSPECT/microCT dual modality small animal scanner (2006)

661 Objectives: SPECT/CT systems have significant potential for small animal imaging investigations involving cancer, cardiovascular physiology, and drug discovery. Small animal imaging requires high resolution imaging with micrometric CT resolution and sub millimeter SPECT resolution. High sensitivity SPECT gamma detectors are required to reduce the SPECT scanning time and the radiation dose. The objectives of the reported work were to construct and evaluate a high spatial resolution, high sensitivity small animal microSPECT/microCT scanner for imaging murine models of mammalian biology and disease. Methods: A novel microSPECT/microCT system previously designed was constructed for small animal imaging. The scanner consists in a rotating gantry, a micro SPECT subsystem, a microCT subsystem, and the associated electronics for SPECT/CT sequential image acquisition. The SPECT subsystem has two Cadmium Zinc Telluride detectors for high-resolution radionuclide imaging of gamma rays with energies up to 250 keV (e.g. In-111 photopeaks). The microCT subsystem incorporates a tungsten x-ray source operated at 60 kV /1mA max current and a CCD camera coupled to a Gadolinium Oxysulphide scintillator. Both subsystems are mounted on a gantry that rotates the imaging elements. The electrical connections are made through a slip ring to allow both circular and helical scanning. The radionuclide and the x-ray detectors can be translated radially using translation stages allowing user selectable field-of-view, resolution, and magnification. Results: The imaging components of the scanner were aligned using laser beams. The system geometric calibration has being tested with resolutions phantoms filled with Tc-99m and In-111. Phantom studies demonstrated spatial resolutions of 700 um (SPECT-Tc-99m) and 50 um (CT). The detectors have an energy resolution of 6.8% FWHM at 140 keV. The efficiency of each pinhole camera was found to be 70cps/MBq (Tc-99m) for a 1mm pinhole at a radius of rotation of 2.5 cm.The circular motion of the gantry has a resolution of 8 arc seconds, and the animal bed has a linear resolution of 50 um. Conclusions: We have implemented a microSPECT/microCT small animal system with high resolution imaging capabilities for imaging function and structure in murine animal models. Important capabilities of this scanner are circular and helical continuous scanning orbits with submillimeter resolution. The system can be used to image radioisotopes up to 250 keV. Research Support (if any): NIH 8 R01 EB000384 and Gamma Medica-Ideas with matching funds from UC Discovery.
Sol-gel techniques for the preparation of ultrafine BaTiO/sub 3/ powders (2003)

It is shown that Ba(ClO/sub 4/)/sub 2/ and LiOC/sub 2/H/sub 5/ can be used as precursors to form Ba(OC/sub 2/H/sub 5/)/sub 2/. In addition, BaTiO/sub 3/ ultrafine powders can be prepared by the sol-gel process from Ba(OC/sub 2/H/sub 5/)/sub 2/ and Ti(OC/sub 4/H/sub 9/)/sub 4/. Ethylene glycol added to ethyl alcohol can greatly increase the solubility of Ba(OC/sub 2/H/sub 5/)/sub 2/, and thus the concentration of Ba(OC/sub 2/H/sub 5/)/sub 2/ and Ti(OC/sub 4/H/sub 9/)/sub 4/ can be increased. This leads to a fast sol-gel process for forming BaTiO/sub 3/ gel. Sol-gel-prepared ultrafine BaTiO/sub 3/ powders crystallize significantly if heated to 750 degrees C, and crystals fully develop at 900 degrees C. Sol-gel-prepared BaTiO/sub 3/ powders are ultrafine narrowly distributed in size, and spherical and polyhedral in appearance.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Keynote 2: Content Delivery Acceleration (2012)

The Internet has evolved into a critical global infrastructure, affecting every facet of how we live and conduct business in all aspects while creating a myriad of entrepreneural possibilities and markets. It has become the platform through which content is pulled and pushed using various end devices. However, streaming content in a timely fashion does present a great challenge, and has a direct impact on the economic vibrance of content providers, service providers, and equipment vendors. This talk will discuss roadblocks in achieving rapid content delivery, cover the state of the art on accelerating content delivery, and present further challenges as the Internet continues to evolve. It will hopefully elicit more interest and efforts in advancing content delivery acceleration that will fuel further technological breakthroughs and economic growth.
Formyl Met-Leu-Phe-Stimulated FPR1 Phosphorylation in Plate-Adherent Human Neutrophils: Enhanced Proteolysis but Lack of Inhibition by Platelet-Activating Factor (2018)

N-formyl-Met-Leu-Phe (fMLF) is a model PAMP/DAMP driving human PMN to sites of injury/infection utilizing the GPCR, FPR1. We examined a microtiter plate format for measurement of FPR1 phosphorylation in adherent PMN at high densities and found that a new phosphosensitive FPR1 fragment, 25K-FPR1, accumulates in SDS-PAGE extracts. 25K-FPR1 is fully inhibited by diisopropylfluorophosphate PMN pretreatment but is not physiologic, as its formation failed to be significantly perturbed by ATP depletion, time and temperature of adherence, or adherence mechanism. 25K-FPR1 was minimized by extracting fMLF-exposed PMN in lithium dodecylsulfate at 4°C prior to reduction/alkylation. After exposure of adherent PMN to a 5 log range of PAF before or after fMLF, unlike in suspension PMN, no inhibition of fMLF-induced FPR1 phosphorylation was observed. However, PAF induced the release of 40% of PMN lactate dehydrogenase, implying significant cell lysis. We infer that PAF-induced inhibition of fMLF-dependent FPR1 phosphorylation observed in suspension PMN does not occur in the unlysed adherent PMN. We speculate that although the conditions of the assay may induce PAF-stimulated necrosis, the cell densities on the plates may approach levels observed in inflamed tissues and provide for an explanation of PAF's divergent effects on FPR1 phosphorylation as well as PMN function.
An Anatomic Study Of Subtalar Instability (1990)

Subtalar instability has been recognized as a cause of ankle symptoms. The purpose of this anatomic study is to determine the ligament damage required to produce subtalar instability, and to define a radiographic technique to demonstrate it. Ten fresh adult cadaver ankles were dissected. Selective sectioning of the calcaneofibular ligament, capsule, and interosseous ligaments of the subtalar joint were done. Radiographic documentation of subtalar opening was recorded, using a lateral and Brodan's view. Sectioning of the calcaneofibular ligament alone produced a 5-mm opening of the subtalar joint. When combined with sectioning of the interosseous ligament, a 7-mm opening was produced. This was reproduced with a plantar flexion-supination load to the foot. Instability of the ankle joint (talar tilting) was produced only when loading caused additional tearing of the anterior talofibular ligament. This study suggests that surgical repairs to correct lateral ankle instability should include repair or substitution of the calcaneofibular ligament if subtalar instability is a consideration.
A scoping review of spatial cluster analysis techniques for point-event data (2013)

Spatial cluster analysis is a uniquely interdisciplinary endeavour, and so it is important to communicate and disseminate ideas, innovations, best practices and challenges across practitioners, applied epidemiology researchers and spatial statisticians. In this research we conducted a scoping review to systematically search peer-reviewed journal databases for research that has employed spatial cluster analysis methods on individual-level, address location, or x and y coordinate derived data. To illustrate the thematic issues raised by our results, methods were tested using a dataset where known clusters existed. Point pattern methods, spatial clustering and cluster detection tests, and a locally weighted spatial regression model were most commonly used for individual-level, address location data (n = 29). The spatial scan statistic was the most popular method for address location data (n = 19). Six themes were identified relating to the application of spatial cluster analysis methods and subsequent analyses, which we recommend researchers to consider; exploratory analysis, visualization, spatial resolution, aetiology, scale and spatial weights. It is our intention that researchers seeking direction for using spatial cluster analysis methods, consider the caveats and strengths of each approach, but also explore the numerous other methods available for this type of analysis. Applied spatial epidemiology researchers and practitioners should give special consideration to applying multiple tests to a dataset. Future research should focus on developing frameworks for selecting appropriate methods and the corresponding spatial weighting schemes.
Iron(iii) sulfate: a stable, cost effective electrode material for sodium ion batteries (2013)

Iron(iii) sulfate, a rhombohedral NASICON compound, has been demonstrated as a sodium intercalation host. This cost-effective material is attractive, as it can be slurry processed in bulk with ball-milling, while utilizing the iron 2(+)/3(+) redox couple, offering stable 3.2 V performance for over 400 cycles.