gebhart/patrepeval huggingface dataset:
Adhesion improvement of tire cord induced by gas plasma (1974)

The adhesion of poly(ethylene terephthalate) (PET) to rubber in tire composites was significantly improved by exposure of the PET to “low-temperature” gas plasmas. Rubber composites built using a single-dip resorcinol–formaldehyde–latex (RFL) adhesive and plasma-treated PET reinforcement were studied. The effects of treatment conditions on this adhesion improvement were examined. The improvement was insensitive to nature of the gas, exposure time, power level, and pressure within the operating limits of the plasma generator. Fiber finish on filaments being treated was detrimental to the adhesion improvement; however, an overcoating of treated filaments with finish was not detrimental. The effects of tire building operations on this adhesion improvement of treated PET were examined. The improvement was found over a wide range of adhesives, adhesive-curing conditions, rubber compositions, and bonding testing conditions.
Primary structure and biological activity of a third gonadotropin-releasing hormone from lamprey brain. (1993)

Previous studies have led to the identification of two molecular forms of GnRH (GnRH-I and II) in the brain of the sea lamprey, Petromyzon marinus. From analysis of these two forms, the primary structure of GnRH-I and the amino acid composition of GnRH-II were determined. We have now isolated a third molecular form of GnRH (GnRH-III) from the brain of this species that is different from GnRH-I and -II. The primary structure of GnRH-III is pGlu-His-Trp-Ser-His-Asp-Trp-Lys- Pro-Gly-NH2. A synthetic decapeptide with this amino acid sequence was chromatographically identical to natural GnRH-III. Intraperitoneal injection of synthetic lamprey GnRH-III (0.1 microgram/g) produced a significant (P < 0.05) elevation of plasma progesterone (31% over basal values) in female lampreys that was comparable to that produced by the same dose of lamprey GnRH-I (36% over basal). The elevation in plasma estradiol produced by lamprey GnRH-III (244% over basal) was significantly (P < 0.05) less than the elevation produced by GnRH-I (322% over basal). We propose based on the biological activity of lamprey GnRH-III in these studies and the occurrence of this peptide during metamorphosis in lampreys, that both lamprey GnRH-I and -III are neurohormones involved in reproduction in lampreys.
SHIPMAI: a secure and high performance mobile agent infrastructure (2002)

The mobile agent (MA) technology is considered a new attracting and challenging paradigm in the area of distributed systems, although it has not yet reached a fully mature stage. In fact, a major problem still limiting the widespread use of mobile agents is the lack of a highly secure and reliable supporting architecture. This paper presents our Java agent infrastructure called SHIPIMAI. It is based on the subdivision of the agent space and the introduction of controlled agent domains. The proposed architecture tries to address the challenging issues in MA concept such as communication and security.
ChemInform Abstract: Bis(trimethylsilyl) Peroxide Extends the Range of Oxorhenium Catalysts for Olefin Epoxidation. (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
High spatial resolution EPI using an odd number of interleaves (1999)

Ghost artifacts in echoplanar imaging (EPI) arise from phase errors caused by differences in eddy currents and gradient ramping during left-to-right traversal of kx(forward echo) versus right-to-left traversal of kx (reverse echo). Reference scans do not always reduce the artifact and may make image quality worse. To eliminate the need for reference scans, a ghost artifact reduction technique based on image phase correction was developed, in which phase errors are directly estimated from images reconstructed separately using only the forward or only the reverse echos. In practice, this technique is applicable only to single-shot EPI that produces only one ghost (shifted 1/2 the field of view from the parent image), because the technique requires that the ghosts do not completely overlap the parent image. For higher spatial resolution, typically an even number of separate k-space traversals (interleaves) are combined to produce one large data set. In this paper, we show that data obtained from an even number of interleaves cannot be combined to produce only one ghost, and image phase correction cannot be applied. We then show that data obtained from an odd number of interleaves can be combined to produce only one ghost, and image phase correction can be applied to reduce ghost intensity significantly. This "odd-number interleaf EPI" provides spatial and temporal resolution tradeoffs that are complementary to, or can replace, those of even-number interleaf EPI. Odd-number interleaf EPI may be particularly useful for MR systems in which reference scans have been unreliable.
Simoloyer® CM100s:Semi-Continuous Mechanical Alloying on a Production Scale part II (1999)

Abstract The production of large quantities of powders for industrial applications, e.g., in paints or soldering materials, especially Cu and Ag particles with a special geometry (flakes) are of high interest. Based on milling experiments resolved by the High Energy (ball) Mill, the Simoloyer CM01–1/2 l, with a grinding unit capacity of 0.5 l for laboratory purpose, a new grinding device, the Simoloyer CMl00sl (capacity 100 liters), has been developed under the same principle. The new device is suitable for a semi-continuous production of mechanically alloyed and mechanically deformed powders (1-3), which is described in part I of this work. Part II focuses on testing and industrial application of the processing equipment as well as on principles regarding productivity. The testing regarding semi-continuous operation using depression has been performed and is discussed in the present paper. The production capability has been determined at 10 kg per 3 minutes. The challenge of the semi-continuous procedure is to get access to this batch-result without additional serving-times. From the present point of view, the route using compression has the highest potential which will be considered in part III of this work. The main processing parameters will lead to a continuous capability of about 4 tons of flake-powder per day (10 hours), which relates to a time-saving factor of approximately 1000 compared to conventional ball-milling and stamping technique. The determination of the energy consumption (energy balance) by use of the special control-software will also be discussed.
Overlapping and CpG Methylation-Sensitive Protein-DNA Interactions at the Histone H4 Transcriptional Cell Cycle Domain: Distinctions between Two Human H4 Gene Promoters (1992)

Transcriptional regulation of vertebrate histone genes during the cell cycle is mediated by several factors interacting with a series of cis-acting elements located in the 5' regions of these genes. The arrangement of these promoter elements is different for each gene. However, most histone H4 gene promoters contain a highly conserved sequence immediately upstream of the TATA box (H4 subtype consensus sequence), and this region in the human H4 gene FO108 is involved in cell cycle control. The sequence-specific interaction of nuclear factor HiNF-D with this key proximal promoter element of the H4-FO108 gene is cell cycle regulated in normal diploid cells (J. Holthuis, T.A. Owen, A.J. van Wijnen, K.L. Wright, A. Ramsey-Ewing, M.B. Kennedy, R. Carter, S.C. Cosenza, K.J. Soprano, J.B. Lian, J.L. Stein, and G.S. Stein, Science, 247:1454-1457, 1990). Here, we show that this region of the H4-FO108 gene represents a composite protein-DNA interaction domain for several distinct sequence-specific DNA-binding activities, including HiNF-D, HiNF-M, and HiNF-P. Factor HiNF-P is similar to H4TF-2, a DNA-binding activity that is not cell cycle regulated and that interacts with the analogous region of the H4 gene H4.A (F. LaBella and N. Heintz, Mol. Cell. Biol. 11:5825-5831, 1991). The H4.A gene fails to interact with factors HiNF-M and HiNF-D owing to two independent sets of specific nucleotide variants, indicating differences in protein-DNA interactions between these H4 genes. Cytosine methylation of a highly conserved CpG dinucleotide interferes with binding of HiNF-P/H4TF-2 to both the H4-FO108 and H4.A promoters, but no effect is observed for either HiNF-M or HiNF-D binding to the H4-FO108 gene. Thus, strong evolutionary conservation of the H4 consensus sequence may be related to combinatorial interactions involving overlapping and interdigitated recognition nucleotides for several proteins, whose activities are regulated independently. Our results also suggest molecular complexity in the transcriptional regulation of distinct human H4 genes.
Analysis of frequency inverter supportability to voltage sags (2018)

This work presents a study about the tolerance of a frequency inverter when submitted to voltage sags, which are events directly related to the electric power quality. The frequency inverters are devices widely used in the industry applications in variable speed drives. According to the magnitude and duration of the voltage sag, the frequency inverters operation can be changed and the industrial process in which they are involved is also affected, and, in some cases, could generate great production losses. In this work, the effects of different voltage sags on a frequency inverter are presented to determine its supportability to these events.
A new approach to low bit rate audio coding using a combined harmonic-multiband-wavelet representation (2003)

In this paper, we present updated results for the combined harmonic-wavelet based audio coder. This coder first approximates the audio frame as a sum of several sinusoids using a harmonic analysis-synthesis scheme. The reconstructed harmonic signal is then subtracted from the original to give a residual, which is analysed using a wavelet filtering scheme. After each step (harmonic analysis and wavelet filtering), the perceptually relevant parameters are quantised and encoded. The total least squares (TLS)-Prony algorithm is used for the harmonic analysis scheme, and cascaded M-band wavelet transforms are used for analysing the residual. At encoding bit rates of 60-70 kbit/s, this audio coder is capable of delivering better results than the MPEG layer II audio coder operating at the much higher bit rate of 128 kbit/s.
Response of bacterial soil communities to a small oil-spill at the Argentine base Jubany on King George Island (Antarctic) (2012)

In October 2009 an oil pipeline running from the fuel depot of Jubany base to the residential and laboratory buildings broke and caused an oil contamination of the ice and snow-covered surrounding. Four months later soil samples were taken in close and greater vicinity to the spill site as well as in the Potter Cove, however, due to snow and melt water runoff through the affected area sampling was limited. One year later snow did not cover the area. Sampling was repeated approximately at the same places and some additional sites. At the spill site the soil even in greater depth was still impregnated by diesel oil whereas at the other sampling points neither smell nor visual appearance of oil residues were noticeable. Correspondingly, the TC% values of the soil samples were very low except for those from the spill site. Measurements of the hydrocarbon content, however, will show how much oil was left. In order to find out if and how the spill affected the cold environment we studied 76 samples for changes in the bacterial community on the basis of the 16S rRNA gene by means of DGGE. Most of the samples showed a high bacterial diversity in 2010 as well as in 2011 with only marginal changes in the taxonomic structure during this period. In contrast, the diversity of the samples near the diesel spill site became clearly reduced. Some strong bands in the DGGE-gels indicated an enrichment of specific bacteria types. Clone libraries revealed that Actinobacteria together with a Betaproteobacterium prevailed in these communities and constituted obviously a natural autochthonous potential for crude oil bioremediation.
cfDNA mutation frequency in early stage breast cancer. (2017)

e23047 Background: Though 93% of patient present with early stage breast cancer (EBC), metastatic recurrence is expected in 7-13%. To prevent estrogen receptor (ER) positive disease recurrence, endocrine therapy (ET) is given after local disease. ET guidelines recently extended therapy —specifically tamoxifen—from 5 years to 10 based on ATLAS and aTTom. This pilot study used blood samples from women 6 months post-ET to determine cell free DNA (cfDNA) mutation prevalence in disease-free patients Methods: Patients with EBC and continued follow-up after ET were recruited from the Magee Women’s Breast Cancer Clinic. Inclusion criteria were EBC, ER+, and completion of ET &gt; 6 months prior to visit; the exclusion criterion was active disease. Patients gave 2 blood samples, placed in Streck and EDTA tubes and processed at 2 laboratory sites for cfDNA. Blood from patients with metastatic breast cancer (MBC) served as controls for mutation detection. cfDNA was amplified for ESR1 and PIK3CA genes. Targeted amplifications underwent digital droplet PCR to identify mutations: 4 for ESR1 (D538G, Y537C/N/S), 2 for PIK3CA (E545K, H1047R) Results: Ten EBC patients &gt; 6 months post-ET (post-EBC; 2/5/3 of stage I/II/III) and 10 MBC patients gave samples. cfDNA yield between plasma isolated from EDTA and Streck tubes (including mutation allele frequencies) was not significantly different (p &gt; 0.05); cfDNA yield from patients with MBC was &gt; 2X higher than post-EBC (p &lt; 0.001). MBC cfDNA had 2 monoclonal and 1 polyclonal (2 different) mutations in ESR1, while post-EBC cfDNA had none Conclusions: This pilot study shows cfDNA can be consistently isolated from Streck or EDTA-processed blood from patients with MBC and post-EBC; however, cfDNA levels are significantly higher in MBC. There were no mutations (ESR1 or PIK3CA) in post-EBC samples, though ESR1 mutations were found in MBC. Further studies are needed to determine if mutations in cfDNA can be found in patients without evidence of disease
Hybrid Multistage Fuzzy Clustering System for Medical Data Classification (2018)

Due to the rapid development in technology nowadays, massive amount of data are available. In medicine, decision making is entirely based on the hidden information in these massive data. For that reason, data mining and machine learning technologies provide powerful tools for knowledge discovery within data. Two main techniques are used interchangeably: clustering and classification. In machine learning, clustering is an unsupervised learning technique while classification is a supervised learning method. These techniques are capable of extracting useful patterns and information which aid the process of data analysis and clinical decisions. This research presents a recent study of these techniques in the medical field during the past five years. Moreover, this paper proposes a hybrid multistage fuzzy clustering system applied to medical data classification. In the proposed system, two fuzzy clustering algorithms specifically FCM and GK were initially employed to obtain the membership values. These weights are then used in the second stage of the system as additional informative features to improve the classification process completed by SVM algorithm. Wisconsin Breast Cancer dataset, real-world application, obtained from UCI were used in the experiments. The results of the experiments show that the additional weights further improve the classification accuracy with 99.06% and 100% sensitivity.
Transient Numerical Modeling of Catalytic Channels (2007)

This paper presents a transient model of catalytic combustion suitable for isolated channels and monolith reactors. The model is a “lumped” two-phase (gas and solid) model where the gas phase is quasi-steady relative to the transient solid. Axial diffusion is neglected in the gas phase; lateral diffusion, however, is accounted for using transfer coefficients. The solid phase includes axial heat conduction and external heat loss due to convection and radiation. The combustion process utilizes detailed gas and surface reaction models. The gas-phase model becomes a system of stiff ordinary differential equations while the solid phase reduces, after discretization, into a system of stiff ordinary differential-algebraic equations. The time evolution of the system came from alternating integrations of the quasi-steady gas and transient solid. This work outlines the numerical model and presents some sensitivity studies on important parameters including internal transfer coefficients, catalytic surface site density, and external heat-loss (if applicable). The model is compared to two experiments using CO fuel: (1) steady-state conversion through an isothermal platinum (Pt) tube and (2) transient propagation of a catalytic reaction inside a small Pt tube. The model requires internal mass-transfer resistance to match the experiments at lower residence times. Under mass-transport limited conditions, the model reasonably predicted exit conversion using global mass-transfer coefficients. Near light-off, the model results did not match the experiment precisely even after adjustment of mass-transfer coefficients. Agreement improved for the first case after adjusting the surface kinetics such that the net rate of CO adsorption increased compared to O2. The CO / O2 surface mechanism came from a sub-set of reactions in a popular CH4 / O2 mechanism. For the second case, predictions improved for lean conditions with increased external heat loss or adjustment of the kinetics as in the first case. Finally, the results show that different initial surface-species distribution leads to different steady-states under certain conditions. These results demonstrate the utility of a lumped two-phase model of a transient catalytic combustor with detailed chemistry.
SYNTHESIS AND BIOLOGICAL ACTIVITY OF POSITION 1 ANALOGS OF LH‐RH (1977)

(Formyl-sarcosine)1-LH-RH (I), (acetyl-sarcosine)1-LH-RH (II), (2-pyrrolidone-4-carboxylic acid)1-LH-RH (III), (N-methyl-2-pyrrolidone-4-carboxylic acid)1-LH-RH (IV, hydroxyproline1-LH-RH (V) and (cylcopentane-carboxylic acid)1-LH-RH (VI) were synthesized by solid phase methods on a benzhydrylamine resin support. Peptides I-IV were assayed for LH- and FSH-releasing activity over a 4-h period after subcutaneous infection into immature male rats in order to detect any prolongation ofactivity. The peptides were found to have the following integrated LH-releasing activities compared with LH-RH: I, 64%; II, 72%; III, 19%; IV, 58%. None of the peptides were found to be longer acting than LH-RH. Peptides V and VI were far less active, 0.001% and 1.4%, respectively.
Editing Brahms (2019)

Is it appropriate to include a chapter on editing Brahms's music in a book about Brahms in Context? In fact, it is not only appropriate but indispensable because it concerns what Brahms left for the present day: his notated music. Furthermore, from the first compositional idea through to publication, his works existed in the 'context' of his contemporaries: friends, acquaintances, copyists, publishers, proofreaders, performers, concert organisers, musicians and critics. Finally, the 'context' should not be limited to his contemporaries because we also need to investigate how his now 'historic' scores were edited after his death and continue to be edited today in the light of philological and editorial premises and methods. Naturally, the question of 'suitable' editing arises, and this must reflect knowledge of current Brahms philology.
Melt Spinning of Poly (caprolacton)/Drag Blends and Drag Lerease Behavior from Blend Fibers. (1999)

Tranilast, N- (3, 4-dimethoxycinnamoyl) anthranilic acid), which suppresses the fibro blast hyperpalsia, and poly (ε-caprolactone) (PCL), a biodegradable polyester with a low melting point, were blended and melt spun to produce the drug releasing biodegradable fibers.Thermal analyses, polarized optical microscope observation, and WAXD analyses revealed that tranilast existed as crystal in PCL solid at room temperature and dissolved in molten PCL at an elevated temperature. This tranilast acted either as a crystal nucleating agent or an impurity which obstracted the crystallization of PCL depending on the tranilast content and the thermal history.Melt-spun fibers of PCL/tranilast blends had mechanical properties which deteriorated with increasing tranilast contents. The drug release rate decreased with increasing draw ratio. This seems to be attributable to high crystallinity of drawn fibers.
Process Technology (2015)

Abstract Process technology is the application of scientific knowledge to processes involved in the transformation of (1) material inputs (i.e., either physical state or physical location), (2) information inputs (e.g. analytical or transactional outcomes) or (3) customer inputs (e.g., physiological or psychological outcomes).
SLiCE: a novel bacterial cell extract-based DNA cloning method (2012)

We describe a novel cloning method termed SLiCE (Seamless Ligation Cloning Extract) that utilizes easy to generate bacterial cell extracts to assemble multiple DNA fragments into recombinant DNA molecules in a single in vitro recombination reaction. SLiCE overcomes the sequence limitations of traditional cloning methods, facilitates seamless cloning by recombining short end homologies (≥15 bp) with or without flanking heterologous sequences and provides an effective strategy for directional subcloning of DNA fragments from Bacteria Artificial Chromosomes (BACs) or other sources. SLiCE is highly cost effective as a number of standard laboratory bacterial strains can serve as sources for SLiCE extract. In addition, the cloning efficiencies and capabilities of these strains can be greatly improved by simple genetic modifications. As an example, we modified the DH10B Escherichia coli strain to express an optimized λ prophage Red recombination system. This strain, termed PPY, facilitates SLiCE with very high efficiencies and demonstrates the versatility of the method.
Automatic registration for multiple sclerosis change detection (2002)

The authors are developing an automated 3D change detection system which accurately registers medical imagery (e.g., MRI or CT) of the same patient from different times for diagnosing pathologies, monitoring treatment, and tracking tissue changes. The system employs a combination of energy-minimization registration techniques to achieve accurate and robust alignment of 3D data sets. The bases for the registration are 3D surfaces extracted from the 3D imagery. Resultant structural changes in the data are identified by using an adaptive segmentation technique to automatically determine tissue morphology. The novel contributions of this work are its end-to-end automation of the change detection process and its high accuracy in monitoring and highlighting such physiological changes. The authors have applied this system to a multiple sclerosis study in which each patient had been imaged over 20 times for the purpose of tracking lesion evolution. This report describes preliminary registration performance analysis using this data.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>