gebhart/patrepeval huggingface dataset:
Wavelength shifts in Hg198 as a function of temperature (1961)

The wavelength shifts for the green (5460A) and blue (4358A) lines emitted from an electrodeless discharge lamp of Hg<sup>198</sup> have been studied as a function of the temperature of the water jacket of the source. The values of the wavelength shifts observed for the green and the blue lines are (8.5±3) 10<sup>-6</sup> A/°C and (2±1) 10<sup>-6</sup> A/°C, respectively.
96-32: Functional Substrates Are Associated with Ventricular Arrhythmia Recurrence Following Ablation (2016)

Introduction: Ventricular tachycardia (VT) recurrence is common following ablation procedures. We hypothesized that substrate identified by functional mapping may identify patients at increased risk. Methods: We analyzed biventricular activation in consecutive patients at VT/PVC ablation using 64-electrode catheters. We performed an IRB-approved rapid pacing protocol until ventricular fibrillation (VF) induction, recorded VF during external defibrillator charging, and then defibrillated VF. Offline, we assessed for regional conduction slowing or onset of functional reentry and used computational phase analysis to quantify spiral wave stability. Patients were then followed for 1 year. Cox-proportional hazards analysis was used to determine predictors of arrhythmia recurrence among variables including presence of CHF, AF, number of VTs, inducible VT after ablation, and maximum spiral wave stability. Results: In 25 patients (EF 48 ± 18%, age 65 ± 8 y), VF (defibrillated at 11 ± 3 s) was induced in 19. VF exhibited a greater proportion of localized reentry in scar or borderzone (82.4%) versus non-scar tissue (27.3%, p = 0.01). ROC analysis determined that a cutoff of 14.5 spiral wave rotations optimized sensitivity (85%) and specificity (87%) for arrhythmia recurrence. Rotor stability was associated with recurrence (86% vs. 11%, p = 0.01; Table 1) but other clinical factors were not. Cox proportional hazards analysis showed that rotor stability was a major predictor of arrhythmia recurrence (p = 0.024), which provided a hazard ratio of 11.8 (1.4, 100). Patient Characteristics Patient Characteristics Conclusion: The presence of functional substrates, identified by VF spiral wave stability, predicts arrhythmia recurrence. Future studies are required to define the precise role of such substrates.
Acute Myeloid Leukemia: A Concise Review (2016)

Acute myeloid leukemia (AML) is a heterogeneous clonal disorder characterized by immature myeloid cell proliferation and bone marrow failure. Cytogenetics and mutation testing remain a critical prognostic tool for post induction treatment. Despite rapid advances in the field including new drug targets and increased understanding of the biology, AML treatment remains unchanged for the past three decades with the majority of patients eventually relapsing and dying of the disease. Allogenic transplant remains the best chance for cure for patients with intermediate or high risk disease. In this review, we discuss the landmark genetic studies that have improved outcome prediction and novel therapies.
Electrochemistry of vitamin B12. 3. One-electron intermediates in the reduction of methylcobalamin and methylcobinamide (1978)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElectrochemistry of vitamin B12. 3. One-electron intermediates in the reduction of methylcobalamin and methylcobinamideDoris Lexa and Jean Michel SaveantCite this: J. Am. Chem. Soc. 1978, 100, 10, 3220–3222Publication Date (Print):May 1, 1978Publication History Published online1 May 2002Published inissue 1 May 1978https://pubs.acs.org/doi/10.1021/ja00478a048https://doi.org/10.1021/ja00478a048research-articleACS PublicationsRequest reuse permissionsArticle Views342Altmetric-Citations95LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Surgery for gastric cancer in patients with coronary heart disease (clinical cases) (2022)

The importance of a multidisciplinary approach in the surgical treatment of patients with severe combined oncological and cardiovascular pathologies is shown. In modern surgery, there is a place for both simultaneous and staged surgical treatment of this category of patients, which should be determined in each specific clinical case and requires an individual multidisciplinary approach with the inclusion in the discussion of such specialists as an oncosurgeon, a chemotherapist, a radiation therapist, a cardiologist/therapist, cardiovascular surgeon, anesthesiologist and resuscitator.&#x0D; Two clinical cases of a two-stage and one-stage surgical approach in the treatment of patients with competing gastric cancer and coronary heart disease are presented. One 47-year-old patient underwent two-stage surgical treatment: stage 1 aortocoronary bypass grafting from mini-thoracotomy (MICS CABG); stage 2 robot-assisted distal subtotal resection of the stomach (Balfour modification) with D2 lymphadenectomy, formation of intracorporeal gastroenteroanastomosis and interintestinal anastomosis according to Brown. Another 74-year-old patient underwent a one-stage surgical intervention: autovenous coronary artery bypass grafting of the anterior interventricular artery, posterior descending coronary artery on a beating heart, without cardiopulmonary bypass + extended-combined gastrectomy with resection of the distal esophagus, resection of the diaphragm, and D2+ lymphadenectomy. The postoperative period proceeded without complications.
OBJECT-ORIENTED PROGRAMMING LANGUAGE FOR FORMALIZATION MODELS OF MOS-TRANSISTOR (2016)

In article is considered possibility of the object-oriented programming language in the making models to formalize procedures of the designing mos-transistor.
Liquid-crystal diffraction gratings using polarization holography alignment techniques (2005)

A method of patterning surfaces for liquid-crystal alignment using a polarization holography exposure on a linear photopolymerizable polymer alignment layer is demonstrated. Three configurations are demonstrated which include registered planar-periodic surface boundary conditions on both surfaces (true polarization gratings), planar-periodic and uniform planary surface boundary conditions, and planar-periodic and homeotropic boundary conditions. Two-dimensional polarization gratings are also demonstrated by orientating planar-periodic alignment layers orthogonally. Passive polarization gratings are also demonstrated using reactive mesogens to capture the periodic order indefinitely. The underlying structure of the configuration is discussed, including the nature of their switching transition (threshold or thresholdless), for all three configurations. A simple phenomenological model is presented to describe the Freedericksz transition for the registered planar-periodic boundary condition case.
A New Synthetic Method of N, &alpha;-Dimethyl-2-methoxyphenethylamine (1957)

Oxidation of 2-propenylanisole, derived from phenol, with Pb3O4 and glacial acetic acid affords 1-(2-methoxyphenyl)-2-propanone. Condensation of nitromethane to this propanone with aluminum amalgam as the reducing agent and ethanol as a solvent, gave N, α-dimethyl-2-methoxyphenethylamine in a good yield.
IP Multicast over Satellite (2003)

Satellites have been very successful for digital broadcast, and it is a natural step to develop IP multicast over satellite to explore the potential of the satellite systems.This paper discusses the issues of IP multicast over satellite, based on IP multicast protocols using different satellite communications systems including DVB-S and DVB-RCS.The paper provides an overview of the networking issues and their interactions.The work is based on the studies of the European IST GEOCAST project within the IST's 5th Framework programme.The paper explains how IP multicast protocols can be implemented over satellite links, looking particularly at the issues involved in implementing IGMP, multicast routing protocols reliable multicast protocols, and security.
Characterization and technological properties of Oenococcus oeni strains from wine spontaneous malolactic fermentations: a framework for selection of new starter cultures (2009)

This article contributes to a better understanding of microbial diversity of O. oeni population in Italian wines and reports a framework to select new potentially O. oeni starters from Italian wines during MLF.
Convergent Azaspirocyclization of Bromoarenes with N-Tosylhydrazones by a Palladium Catalyst (2021)

1-Azaspirocyclic compounds have gained attention in chemistry and drug discovery fields. In this manuscript, the development of a Pd-catalyzed dearomative azaspirocyclization of bromoarenes bearing an aminoalkyl group with &lt;i&gt;N&lt;/i&gt;-tosylhydrazones is described. The present method enables azaspirocyclization with the introduction of carbon substituents, achieving the convergent synthesis of 1-azaspirocycles. This method allowed furan, thiophene, and naphthalene cores to generate the corresponding 1-azaspirocycles. The obtained azaspirocycles from furans were further elaborated &lt;i&gt;via&lt;/i&gt; an acid-catalyzed rearrangement to afford 1-azaspirocyclopentenones.
Correction: Enhanced photocatalytic activity of a self-stabilized synthetic flavin anchored on a TiO2 surface (2016)

Correction for 'Enhanced photocatalytic activity of a self-stabilized synthetic flavin anchored on a TiO2 surface' by Manjula Pandiri et al., Phys. Chem. Chem. Phys., 2016, 18, 18575-18583.
Splenectomy for hematologic depression in lymphocytic lymphoma and leukemia (1975)

Fifty patients with lymphocytic lymphoma and chronic lymphocytic leukemia underwent splenectomy for various combinations of anemia, thrombocytopenia, and leukopenia. All of these patients had advanced lymphoproliferative disease, and most had infiltration of bone marrow by neoplastic cells. Good response in all hematologic parameters was obtained in 27 of 48 evaluable patients. An additional 13 patients responded in one or two parameters; there were only 8 complete failures. The over-all surgical mortality was 8%. The median duration of response was 4 months, and the mean, 7 months. Increased tolerance to further antitumor therapy and a decreased transfusion requirement were seen among responding patients. Those patients with anemia who had evidence of shortened erythrocyte survival and splenic sequestration of 51Cr-labelled erythrocytes uniformly responded with rises in hemoglobin. However, half of the patients with negative splenic sequestration also showed improvement of anemia. Preoperative diagnostic studies failed to predict favorable responses of patients with thrombocytopenia or leukopenia. The classical criteria for the diagnosis of hypersplenism are not applicable in many cases of neoplastic lymphoproliferative disease; splenectomy could have been considered "contraindicated" in most of the patients in this series. We conclude that splenectomy is worth undertaking in patients with lymphoproliferative disease complicated by hematologic depression regardless of marrow findings or the results of other diagnostic studies.
False-positive elimination for computer-aided detection of pulmonary micronodules (2006)

Computed Tomography (CT) is generally accepted as the most sensitive way for lung cancer screening. Its high contrast resolution allows the detection of small nodules and, thus, lung cancer at a very early stage. Due to the amount of data it produces, however, automating the nodule detection process is viable. The challenging problem for any nodule detection system is to keep low false-positive detection rate while maintaining high sensitivity. In this paper, we first describe a 3D filter-based method for pulmonary micronodule detection from high-resolution 3D chest CT images. Then, we propose a false-positive elimination method based on a deformable model. Finally, we present promising results of applying our method to various clinical chest CT datasets with over 90% detection rate. The proposed method focuses on the automatic detection of both calcified (high-contrast) and noncalcified (low-contrast) granulomatous nodules less than 5mm in diameter.
Simple Procedure for Automatic Detection of Unstable Alleles in the Myotonic Dystrophy and Huntington's Disease Loci (2006)

Human neurodegenerative and neuromuscular disorders are associated with a class of gene mutations represented by expansion of trinucleotide repeats. DNA testing is important for the diagnosis of these diseases because clinical discrimination is complicated by their late onset and frequently overlapping symptomatology. However, detection of pathologic alleles expanded up to several thousand trinucleotides poses a challenge for the introduction of rapid, fully automatic, and simple DNA diagnostic procedures. Here we propose a simple two-step polymerase chain reaction (PCR) protocol for rapid molecular diagnostics of myotonic dystrophy, Huntington's disease, and possibly also other triplet expansion diseases. Standard PCR amplification with target repeat flanking primers is used for the detection of alleles of up to 100 repeats; next, triplet-primed PCR is applied for detection of larger expansions. Automated capillary electrophoresis of amplicons allows rapid discrimination between normal, premutated and expanded (CTG/CAG)(n) alleles. Using the suggested protocol, the expanded allele was successfully detected in all test DNA samples with known genotypes. Our experience demonstrates that the suggested two-step PCR protocol provides high sensitivity, specificity, and reproducibility; is significantly less time-consuming; is easier to perform; and provides a better basis for automation than previous methods requiring Southern analysis. Therefore, it can be used for confirmation of uncertain clinical diagnoses, for prenatal testing in at-risk families, and, generally in research on these diseases.
Mesenchymal Stem Cell Isolation and Characterization of Dental Pulp from Fractured Permanent Anterior Teeth Due to Trauma (2021)

Amaç: İnsan dental pulpa mezenkimal kök hücrelerin (İDPMKH) sağlıklı pulpa dokularından izole edildiğine dair çok sayıda araştırma olmakla birlikte, travma nedeniyle kırılan dişlerden İDPMKH'lerin izolasyonuna ilişkin çalışma çok sınırlı sayıdadır. Bu çalışmada, travma nedeniyle dişleri kırılmış hastanın kanal tedavisi sırasında elde edilen pulpa dokularından, mezenkimal kök hücre (MKH) izolasyonu yapılıp yapılamayacağı test edildi. Gereç ve Yöntemler: Beş gün önce düştüğü için üst çene santral dişleri (#11, #21) kırılan 15 yaşındaki kadın hasta, ağrı şikâyetiyle pedodonti kliniğine başvurdu. Kırığı görmek, izolasyonu sağlamak ve düzgün bir şekilde restore etmek için krestal alveoler kemiğe osteotomi yapılması için flep cerrahisine karar verildi. Dişler, kanal tedavisi yapılmadan restore edilemeyeceği için pulpa dokusu ekstirpe edildi. Avasküler görünümlü pulpa dokuları eksplant yöntemiyle kültür ortamına alındı ve hücre büyümesi gözlemlendi. Hücrelerin 3. pasajından sonra RNA izole edildi ve MKH'ye özgü hücre yüzey belirteçleri gerçek zamanlı polimeraz zincir reaksiyonu [real-time polymerase chain reaction (RT-PCR)] ile çalışıldı. Ayrıca hematopoietik kök hücre yüzey belirteçleri doğrulama için değerlendirildi. Bulgular: RT-PCR sonuçları, hücrelerin MKH spesifik yüzey belirteçlerini (CD73, CD90, CD105) eksprese ettiğini ve hematopoietik kök hücre yüzey belirteçlerinin (CD34, CD45), ekspresyonunun çok düşük düzeyde olduğunu gösterdi. Sonuç: Travma görmüş kırılmış dişlerden MKH izolasyonunun yapılabilmesi, otolog dental pulpa MKH izole edilerek, hücre temelli kanal tedavilerinin mümkün olabileceğini düşündürmektedir. Bu yaklaşım da diş hekimliğinde travma hastalarının tedavisinde pulpanın revaskülarizasyonu ve rejenerasyonu açısından umut vaat edici görünmektedir.
Long Term Functional Outcomes of the Capanna Technique for Pediatric Limb Salvage (2012)

INTRODUCTION: Large intercalary bone defects have historically been reconstructed with massive cadaveric allograft, however this practice is associated with multiple complications including infection, fracture and nonunion (1–3). In contrast, the Capanna technique combines the use of large cadaveric allograft with an intermedullary vascularized fibular flap to allow for immediate rigid fixation of the allograft, but allow for the potential of accelerated bony union through the fibula flap (Fig. 1 and 2) (4). METHODS: Between 1997- 2009, we operated the lower limb of 17 children with Capanna technique. Average age was 11.05 ± 4.02 years at the time of operation. All the patients were skeletally immature. We collected data retrospectively and our follow up ranged between 20 and 135 months (Mean 71.46 ± 37.14 months). All the patients' tumours were biopsied before the surgery and appropriate chemotherapy was started before limb salvage and continued 3 weeks after the surgery. METHODS: 8 were femur (47%) and 9 were tibia (53%). According to the pathology reports, 45% of the tumors (8 patients) were osteosarcoma; 35% (6 patients) were Ewing's sarcoma and there was one adamantinoma, one chondrosarcoma and one osteofibrous dysplasia. Mean excised tumor volume was 120.62 ± 205.05 cm3. The mean bone defect was 14.34 ± 4.71 cm. Mean length of harvested free fibula was 18.56 ± 3.69. All the patients healed well except one patient whose graft was replaced by bone allograft 31 months after the limb salvage surgery. We excluded this patient and last two patients from union time analysis because their follow-up hasn't reached to one year. Mean union time for the allograft placed in femur was 12.41 ± 5.47 months and in tibia was 14.43 ± 6.5 months. Mean union time for the fibula flap placed in femur was 8.16 ± 2.48 months and in tibia was 6.56 ± 2.61 months. 2 of the patients had distant metastasis to lung, sphenoid bone and hand. 7 patients re-operated because of the allograft non-union. We did not encounter any wound or bone infection. All limbs were salvaged. At final follow-up, only two patients had more than 2cm of leg length discrepancy. Mankin score was excellent for 87% of patients and good for the rest. CONCLUSION: Compared to other long bone reconstruction methods, the Capanna technique is a single step, effective and durable limb salvage surgery that has earlier bone union time.Figure 1: Vascularized fibula flap was inserted into the cadaveric allograft and a window was created for the vascular pedicle.Figure 2: Bone defect was filled with the combined cadaveric allograft and free fibula flap and fixed with Less Invasive Stabilization System (LISS). The pedicle was ready for the anastomosis.
Safety and Immunogenicity of Adult Formulation Tetanus and Diphtheria Toxoids Adsorbed Combined with Acellular Pertussis Vaccine Following Blood and Marrow Transplantation in Adults (2008)

Introduction: Many long-term survivors after stem cell transplantation (SCT) are infected with HCV. It has been reported that a high proportion of these patients develop late occurring liver cirrhosis. Treatment options include interferon with or without the addition of ribavirin but the knowledge about these options' effectiveness is limited. Therefore in 1992, the Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation (EBMT) initiated a prospective study of HCV infected SCT patients having survived at least 6 months after SCT. The intention is to every five years ask for follow-up on living patients. Two hundred and fortyseven patients were included in the study cohort between 1992 and 1997. Report: This is the 3rd report of this cohort. Due to limited followup data, 49 patients have been excluded. Thus, the report is based on 198 patients with a median follow-up of 16 years (0.52-32.8). The Kaplan-Meier estimate of survival is 73.9%. Forty patients have died of whom 8 have been reported to have died from liver associated complications including two after liver transplantation. One additional patient is alive after liver transplantation. Eighty-two patients have been treated with interferon with or without the addition of ribavirin or with ribavirin alone. Thirty-six of eighty-two patients became HCV PCR negative of whom 4 have relapsed with positive HCV PCR. The side effect profile was similar to other patient populations treated for HCV. Conclusion: In this prospectively followed cohort, the prognosis of chronic HCV infection was quite favourable. Treatment is feasible and associated with acceptable efficacy and toxicity.
Microneurography: how the technique developed and its role in the investigation of the sympathetic nervous system (2004)

A historical review is given of the development of microneurography and its application for studies of sympathetic nerve activity in humans.
Fluorescent polymer particles incorporating pyrene derivatives (2007)

Abstract Fluorescent polymer particles incorporating pyrene and alkynylpyrenes were prepared by miniemulsion polymerization of styrene. The pyrenes were simply dissolved in styrene monomer and then added to the reaction mixture in a vessel, followed by ultrasonication and the polymerization. The pyrenes were incorporated in the polystyrene particles and gave monomer fluorescence emission. The fluorescent particles incorporating the alkynylpyrenes, which have high fluorescence quantum yield and short fluorescence lifetime, showed the same fluorescence emission intensity under air and nitrogen. The fluorescence of the alkynylpyrenes in the polymer particles will not be quenched by molecular dioxygen in contrast to that in organic solvents. Incorporation of fluorophore into polymer particles will protect the fluorophore from its undesirable interaction with oxygen, affording the particles highly fluorescent even under air. © 2008 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 46: 1470–1475, 2008
Kinect-based visual communication system (2012)

Nowadays, most existing online instant messaging tools, such as Live Messenger, Google Talk, Yahoo Messenger, ICQ, enable people to communicate with each other no matter where and when they are. However, it is still difficult for people who speak different native languages and do not understand each other's to communicate smoothly. It could be more difficult when people with hearing impairment are trying to use those tools. Moreover, users' hands are usually tied up with keyboard and mouse to keep typing messages. To deal with these disadvantages, we design a Kinect-based Visual Communication System (KVCS), which contains following features: (1) Kinect-based sign language recognition module to make deaf-mute persons be able to chat. (2) Kinect-based expression recognition module to enrich online chatting experiences at the same time.(3) Kinect-based speech recognition module to free users' hands when chatting. (4) Cross-media multi-lingual visualized translation module to enable users to catch the meanings of conversation much easier. Experiments on our system demonstrate that this novel KVCS provides a powerful and efficient communication function and a wonderful user experience.