gebhart/patrepeval huggingface dataset:
Conceptual Modeling of Events for Active Information Systems (2009)

Active information systems participate in the operation and management of business organizations. They create conceptual objects that represent social constructions, such as agreements, commitments, transactions, and obligations. They determine and ascribe attributes to both conceptual and concrete objects (things) that are of interest to the organization. Active information system infer conclusions based on the application of socially constructed and mutable rules constituting organizational policies and procedures that govern how conceptual and concrete objects are affected when defined and identified events occur. The ontological foundations for active information systems must include constructs that represent concrete and conceptual objects, their attributes, and the events that affect them. Events are a crucial component of conceptual models that represent active information systems. The representation of events must include ascribed attributes representing data values inherent in the event as well as rules defining how conceptual and concrete objects are affected when the event occurs. The state-history of an object can then be constructed and reconstructed by the sequence of events that have affected it. Alternate state-histories can be generated based on proposed or conjectured rule modifications, enabling a reinterpretation of history. Future states can be predicted based on proposed or conjectured events and event definitions. Such a conceptualization enables a parsimonious mapping between an active information system and the organizational system in which it participates.
Interferometric all-optical switches for ultrafast signal processing (1998)

All-optical switches find applications in ultrahigh-speed network-user interfaces and in specialized high-speed processors, such as data regenerators and encryptors and microwave signal generators. We describe a semiconductor optical-amplifier-based single-arm interferometric switch called the ultrafast nonlinear interferometer. We discuss how the gain and the refractive-index nonlinearities in semiconductor optical amplifiers have an impact on the all-optical switch design, and we review experimental results obtained with the ultrafast nonlinear interferometer.
The strain distribution for the natural and implanted hip joint articulation (2012)

"The strain distribution for the natural and implanted hip joint articulation." Computer Methods in Biomechanics and Biomedical Engineering, 15(sup1), pp. 363–364Keywords: experimental modelship joint arthroplastystrain Acknowledgements The authors gratefully acknowledge to the PTDC/EME-PME/112910/2009 and PTDC/EME-PME/112977/2009.
Granzyme B, a novel mediator of allergic inflammation: its induction and release in blood basophils and human asthma (2006)

Histamine, leukotriene C4, IL-4, and IL-13 are major mediators of allergy and asthma. They are all formed by basophils and are released in particularly large quantities after stimulation with IL-3. Here we show that supernatants of activated mast cells or IL-3 qualitatively change the makeup of granules of human basophils by inducing de novo synthesis of granzyme B (GzmB), without induction of other granule proteins expressed by cytotoxic lymphocytes (granzyme A, perforin). This bioactivity of IL-3 is not shared by other cytokines known to regulate the function of basophils or lymphocytes. The IL-3 effect is restricted to basophil granulocytes as no constitutive or inducible expression of GzmB is detected in eosinophils or neutrophils. GzmB is induced within 6 to 24 hours, sorted into the granule compartment, and released by exocytosis upon IgE-dependent and -independent activation. In vitro, there is a close parallelism between GzmB, IL-13, and leukotriene C4 production. In vivo, granzyme B, but not the lymphoid granule marker granzyme A, is released 18 hours after allergen challenge of asthmatic patients in strong correlation with interleukin-13. Our study demonstrates an unexpected plasticity of the granule composition of mature basophils and suggests a role of granzyme B as a novel mediator of allergic diseases.
The Persistence of Complement in Aged Sera,, (1953)

Summary and Conclusions It has been demonstrated that nitrogen which can fix to specific precipitates persists in rabbit, human, and guinea pig sera for long periods of time. The reasons for regarding this as complement nitrogen are discussed. The persistence of complement nitrogen is greatest in rabbit serum. Only rabbit complement affected the precipitation of soluble rabbit antigen-antibody complexes. It has been postulated that the effect of an anticomplementary substance present in sera decreases with age, dilution, and increase in temperature. The effect of versene on the contribution of complement nitrogen to specific precipitates by guinea pig and some human sera has been confirmed. However, versene in the concentrations used had no effect on the complement of rabbit serum.
Flow cytometric studies on modulation of cellular adriamycin retention by phenothiazines. (1985)

Phenothiazines (chlorpromazine and trifluoperazine) enhance the cellular retention and cytotoxicity of adriamycin in P388/S and P388/R cells. Effects on the resistant cells are more pronounced than those on the sensitive cells. Multiparametric flow-cytometric determination of cellular Adriamycin fluorescence shows that the phenothiazine effects are not uniform in a cell population, and cells in later part of the cell cycle traverse (S and G2/M), mitogen-stimulated lymphocytes (as compared to nonstimulated lymphocytes), and ascites (as compared to splenocytes) have greater sensitivity to phenothiazine effects on Adriamycin retention.
Padé approximants and exact two-locus sampling distributions (2012)

For population genetics models with recombination, obtaining an exact, analytic sampling distribution has remained a challenging open problem for several decades. Recently, a new perspective based on asymptotic series has been introduced to make progress on this problem. Specifically, closed-form expressions have been derived for the first few terms in an asymptotic expansion of the two-locus sampling distribution when the recombination rate <i>ρ</i> is moderate to large. In this paper, a new computational technique is developed for finding the asymptotic expansion to an <i>arbitrary order</i>. Computation in this new approach can be automated easily. Furthermore, it is proved here that only a finite number of terms in the asymptotic expansion is needed to recover (via the method of Padé approximants) the <i>exact</i> two-locus sampling distribution as an analytic function of <i>ρ</i>; this function is exact for all values of <i>ρ</i> ∈ [0, ∞). It is also shown that the new computational framework presented here is flexible enough to incorporate natural selection.
Cognitive sequelae in acute respiratory distress syndrome patients with and without recall of the intensive care unit (2007)

Some critically ill patients have dramatic recollections of the intensive care unit (ICU), whereas 23-50% have little or no recollection of their ICU stay. In addition, cognitive impairments are common following critical illness and ICU treatment. Little is known regarding the relationship between cognitive sequelae and ICU recall. We assessed recall of the ICU and its relationship to cognitive functioning at hospital discharge and 1 and 2 years after discharge in 70 consecutive acute respiratory distress syndrome (ARDS) patients. Seventeen patients (24%) had no recall of the ICU. Patients without ICU recall had increased rates of cognitive sequelae at hospital discharge and 1-year follow-up compared with the ICU recall group. Patients without ICU recall had a greater magnitude of cognitive impairments at hospital discharge, but not at 1- or 2-year follow-up. Profile analysis showed significant group differences in general intellectual functioning, executive function, processing speed, and spatial skills at hospital discharge, but not at 1- or 2-year follow-up. Estimated premorbid intelligence scores were inversely related to the magnitude of cognitive sequelae, suggesting greater "cognitive reserve" in patients with fewer cognitive decrements.
Octahedral Coordination of Halide Ions (I-, Br-, Cl-) Sandwich Bonded with Tridentate Mercuracarborand-3 Receptors (2001)

The "anti-crown" B-hexamethyl 9-mercuracarborand-3 (1) was shown to complex halide ions (I-, Br-, Cl-) in an eta(3)-sandwich fashion. Symmetry-allowed interactions of the filled halide ion p-orbitals and the corresponding empty mercury p-orbitals result in three equivalent p(Hg)-p(halide)-p(Hg) three-center two-electron bonds and a sandwich structure. The molecular structures of [Li.(H(2)O)(4)][1(2).I].2CH(3)CN, MePPh(3)[1(2).Br].((CH(3))(2)CO)(2).(H(2)O)(2), and PPN[1(2).Cl] were determined by single-crystal X-ray diffraction studies. Compound [Li.(H(2)O)(4)][1(2).I].2CH(3)CN crystallized in the triclinic space group P-1, a = 13.312(8) A, b = 13.983(9) A, c = 13.996(9) A, alpha = 61.16(2) degrees, beta = 82.34(2) degrees, gamma = 86.58(2) degrees, V = 4365(2) A(3), Z = 1, R = 0.063, and R(w) = 0.171. Compound MePPh(3)[1(2).Br].((CH(3))(2)CO)(2).(H(2)O)(2) crystallized in the monoclinic space group C2/c, a = 24.671(8) A, b = 17.576(6) A, c = 26.079(8) A, beta = 106.424(6) degrees, V = 10847(6) A(3), Z = 8, R = 0.0607, and R(w) = 0.1506. Compound PPN[1(2).Cl] crystallized in the monoclinic space group C2/m, a = 37.27(2) A, b = 29.25(1) A, c = 10.990(4) A, beta = 100.659(7) degrees, V = 11774(8) A(3), Z = 4, R = 0.0911, and R(w) = 0.2369.
EGFR-Mediated Carcinoma Cell Metastasis Mediated by Integrin αvβ5 Depends on Activation of c-Src and Cleavage of MUC1 (2012)

Receptor tyrosine kinases and integrins play an essential role in tumor cell invasion and metastasis. We previously showed that EGF and other growth factors induce human carcinoma cell invasion and metastasis mediated by integrin avb5 that is prevented by Src blockade MUC1, a transmembrane glycoprotein, is expressed in most epithelial tumors as a heterodimer consisting of an extracellular and a transmembrane subunit. The MUC1 cytoplasmic domain of the transmembrane subunit (MUC1.CD) translocates to the nucleus where it promotes the transcription of a metastatic gene signature associated with epithelial to mesenchymal transition. Here, we demonstrate a requirement for MUC1 in carcinoma cell metastasis dependent on EGFR and Src without affecting primary tumor growth. EGF stimulates Src-dependent MUC1 cleavage and nuclear localization leading to the expression of genes linked to metastasis. Moreover, expression of MUC1.CD results in its nuclear localization and is sufficient for transcription of the metastatic gene signature and tumor cell metastasis. These results demonstrate that EGFR and Src activity contribute to carcinoma cell invasion and metastasis mediated by integrin avb5 in part by promoting proteolytic cleavage of MUC1 and highlight the ability of MUC1.CD to promote metastasis in a context-dependent manner. Our findings may have implications for the use and future design of targeted therapies in cancers known to express EGFR, Src, or MUC1.
Activity prediction for in-home activity monitoring (2008)

In this paper, we propose an extension to a generic model developed for elaborating person's lifestyle patterns and changes in those patterns which could be related to health decline. The baseline model aims at a better understanding of the behaviours engaged in various housing contexts such as conventional housing or Assisted Living (AL) facilities and exploring irregularities within the life rhythm of the resident's everyday life activities. The model, embedded into a customized software program, has been extended to predict the progression of a particular activity on the basis of a circadian period (24- hour period) in order to detect unexpected events such as slowdowns or disruptions which could indicate changes in health status, cognitive or motor impairments. The objective is to help caregivers provide better assessment of functional health status and preventative assistance. A case study, elaborated through software simulations, is presented to show the potential of the software application to determine life patterns in conjunction with activity trend indicators that may indicate health deterioration. (4 pages)
Consistency and plausible reasoning (1983)

The usual approach to plausible reasoning is to associate a validity measure with each fact or rule, and to compute from these a validity measure for any deduction that is made. This approach is shown to be inappropriate for some classes of problems, particularly those in which the evidence is not internally consistent. Two current plausible reasoning architectures are summarized and each applied to the same small task. An analysis of the performance of these systems reveals deficiencies in each case. The paper then outlines a new approach based on the discovery of consistent subsets of the given evidence. This system can be used either in isolation or in conjunction with a validity-propagating architecture. Comparative results from implementations of all three systems are presented.
A low-frequency directional flextensional transducer and line array (1996)

A unique low-frequency (900 Hz) Class IV flextensional transducer which produces enhanced far-field pressure on one side and canceled far-field pressure on the other side has been developed. The transducer radiating surface consists of an elliptical aluminum shell and a piezoelectric stack along its major axis with two active sections and one inactive section. The directionality is achieved by exciting the shell into an omnidirectional and dipole operation by driving the ceramic stack into both extensional and bending modes. Both measurements and modeling on this device show a front to back pressure ratio of more than 25 dB, producing cardioid type radiation patterns over an octave band. The measured mechanical Q, coupling coefficient, and electroacoustic efficiency were found to be approximately 8%, 0.25%, and 80%, respectively, and the transducer produced a source level of 215 dB re: 1 μPa/m. Six of these transducers were placed in a closely packed line array. The array successfully produced narrow directional sound beams with a front to back ratio greater than 25 dB and a source level of 225 dB re: 1 μPa/m. [Work supported, in part, through a U. S. Navy SBIR contract.]
Oxidative status and malondialdehyde in β‐thalassaemia patients (2002)

Our results confirm the peroxidative status generated by iron overload in thalassaemia patients and highlight the rapid formation of marked amounts of free MDA despite the chelation therapy in TM patients.
Salivary defense mechanisms in juvenile periodontitis (1990)

The local, saliva-associated defense mechanisms of 28 juvenile periodontitis (JP) patients and their age- and sex-matched controls were studied. Lysozyme, lactoferrin, salivary peroxidase, myeloperoxidase, and thiocyanate concentrations were determined from both whole saliva and parotid saliva. The total concentrations of salivary IgA, IgG, and IgM were assayed. The periodontal condition and the salivary flow rates were registered. Among the JP patients, a significantly elevated concentration of IgG was found in parotid saliva but not in whole saliva. Salivary peroxidase activities were significantly low both in the whole and in the parotid saliva samples of the JP patients, and leukocyte-derived myeloperoxidase was present in significantly low amounts in whole saliva of these patients. Because both glandular (salivary peroxidase) and polymorphonuclear-cell-derived (myeloperoxidase) enzyme activities were low among the JP patients, suppressed peroxidase-mediated host defense mechanisms could be characteristic of JP.
Angle correction for small animal tumor imaging with spatial frequency domain imaging (SFDI) (2016)

Spatial frequency domain imaging (SFDI) is a widefield imaging technique that allows for the quantitative extraction of tissue optical properties. SFDI is currently being explored for small animal tumor imaging, but severe imaging artifacts occur for highly curved surfaces (e.g. the tumor edge). We propose a modified Lambertian angle correction, adapted from the Minnaert correction method for satellite imagery, to account for tissue surface angles up to 75°. The method was tested in a hemisphere phantom study as well as a small animal tumor model. The proposed method reduced µa and µs` extraction errors by an average of 64% and 16% respectively compared to performing no angle correction, and provided more physiologically agreeable optical property and chromophore values on tumors.
BFS에 기반한 포스트 랭킹: 알고리즘 및 성능 평가 (2015)

이 논문은 2015년도 정부(미래창조과학부)의 재원으로 한국연구재단(No. NRF-2014R1A2A1A10054151) 및 미래창조과학부 및 정보통신기술진흥센터의 대학ICT연구센터육성 지원사업(IITP-2015-H8501-15-1013)의 연구결과로 수행되었습니다.
Determining building interior structures using compressive sensing (2013)

We consider imaging of the building interior structures using compressive sensing (CS) with applications to through-the-wall imaging and urban sensing. We consider a monostatic synthetic aperture radar imaging system employing stepped frequency waveform. The proposed approach exploits prior information of building construction practices to form an appropriate sparse representation of the building interior layout. We devise a dictionary of possible wall locations, which is consistent with the fact that interior walls are typically parallel or perpendicular to the front wall. The dictionary accounts for the dominant normal angle reflections from exterior and interior walls for the monostatic imaging system. CS is applied to a reduced set of observations to recover the true positions of the walls. Additional information about interior walls can be obtained using a dictionary of possible corner reflectors, which is the response of the junction of two walls. Supporting results based on simulation and laboratory experiments are provided. It is shown that the proposed sparsifying basis outperforms the conventional through-the-wall CS model, the wavelet sparsifying basis, and the block sparse model for building interior layout detection.
Solution of thermo‐fluid problems by collocation with local pressure correction (2008)

Purpose The purpose of this paper is to explore the application of the mesh‐free local radial basis function collocation method (RBFCM) in solution of coupled heat transfer and fluid‐flow problems. Design/methodology/approach The involved temperature, velocity and pressure fields are represented on overlapping five nodded sub‐domains through collocation by using multiquadrics radial basis functions (RBF). The involved first and second derivatives of the fields are calculated from the respective derivatives of the RBFs. The energy and momentum equations are solved through explicit time stepping. Findings The performance of the method is assessed on the classical two dimensional de Vahl Davis steady natural convection benchmark for Rayleigh numbers from 10 3 to 10 8 and Prandtl number 0.71. The results show good agreement with other methods at a given range. Originality/value The pressure‐velocity coupling is calculated iteratively, with pressure correction, predicted from the local mass continuity equation violation. This formulation does not require solution of pressure Poisson or pressure correction Poisson equations and thus much simplifies the previous attempts in the field.
A New Convenient Method for the Preparation of Enamides from N‐Allylamides. (2002)

Abstract For Abstract see ChemInform Abstract in Full Text.
First Complete Genome Sequence of Arracacha virus A Isolated from a 38-Year-Old Sample from Peru (2017)

We present here the first complete genomic sequence of <i>Arracacha virus A</i> from a Peruvian arracacha sample collected in 1975 and compare it with the genomes of other nepoviruses. Its RNA1 and RNA2 both had greatest amino acid identities with those of the subgroup A nepovirus <i>Melon mild mottle virus</i>.
Role of core-disruptive accidents in design and licensing of LMFBRs (1976)

The role of core-disruptive accidents (CDAs) in design and licensing of liquid-metal-cooled fast breeder reactors is reviewed, including a description of CDA initiators, likely accident paths, core-meltdown energetics, and radiological consequences. It is concluded that (1) the probabilities of initiators leading to core meltdown should and can be made sufficiently low (objective, less than 10/sup -6/ per reactor-year) to reduce them to Class 9 accidents, (2) best-estimate analysis including design considerations should and can demonstrate the unlikelihood (objective, less than 10/sup -2/) of a postulated core meltdown leading to substantial energetics that would challenge the energy absorption capability provided by the primary-system design, i.e., the absence of energetic hydrodynamic disassembly and/or energetic fuel--coolant interactions, (3) the principal basis for the primary-system design should be set by functional requirements where any weak links in the resulting design should be upgraded to give an overall consistent system with an optimum energy absorption capability (essentially current practice) and not by arbitrary CDA energetics, and (4) on the basis of best-estimate analysis including design considerations, the objective should and can be to demonstrate long-term containment capability of the fuel debris following a postulated core-meltdown accident. This balanced approach is believed necessary, at least inmore » the near term, to adequately demonstrate that the safety objective that the occurrence of radiological consequences outside the plant boundary in excess of acceptable levels must be less than 10/sup -6/ per reactor-year has indeed been achieved.« less
Conceptualizing a Real-Time Remote Cardiac Health Monitoring System (2016)

In today's technology, even leading medical institutions diagnose their cardiac patients through ECG recordings obtained at healthcare organizations (HCO), which are costly to obtain and may miss significant clinically-relevant information. Existing long-term patient monitoring systems (e.g., Holter monitors) provide limited information about the evolution of deadly cardiac conditions and lack interactivity in case there is a sudden degradation in the patient's health condition. A standardized and scalable system does not currently exist to monitor an expanding set of patient vitals that a doctor can prescribe to monitor. The design of such a system will translate to significant healthcare savings as well as drastic improvements in diagnostic accuracy. In this chapter, we will propose a concept system for real-time remote cardiac health monitoring, based on available and emerging technologies today. We will analyze the details of such a system from acquisition to visualization of medical data.
Stopping powers and ranges of electrons and positrons (1982)

Tables of stopping powers and related data are given for electrons in 25 elements and 46 mixtures and compounds, and for positrons in 8 materials. The tables include: (1) collision stopping powers (ionization and excitation losses); (2) radiative stopping powers (bremsstrahlung losses); (3) total stopping powers; (4) ranges (rectified pathlengths computed in the continuous- slowing-down approximation) ;
The acentric nature of trans-stilbazole crystals and the origin of its NLO response (2001)

The X-ray crystal structure and the second order nonlinear optical response of trans-stilbazole are discussed. Given that diffraction intensities are completely insensitive to any small distortion from centrosymmetry, stilbazole X-ray diffraction data are better modelled in the centrosymmetric P21/c space group and cannot be used to distinguish between alternative acentric options. However, second harmonic generation, notable in itself, sheds light on the acentric nature of the crystals and allows the most reasonable structural model to be selected. A previously unobserved low energy photoemission, probably due to through-space charge transfers, is also reported.