gebhart/patrepeval huggingface dataset:
Preliminary assessment of the earth’s surface movement in the impact zone of a subway tunnel construction (2020)

Abstract Numerical modeling of the displacement of the earth’s surface during the construction of deep tunnels is considered on the example of one of the Moscow metro lines. Based on the results of numerical simulation of the driving of one and two tunnels using several calculation schemes, the forecast parameters of the displacement trough, such as subsidence, slopes, curvature, horizontal deformations of the earth’s surface, are determined. According to the criteria of deformations of the earth’s surface, a tunnel influence zone is constructed. In the influence zone of tunnels, it is necessary to create observation stations for surveying (geodetic) monitoring of subsidence of buildings and the earth’s surface, including using automated monitoring systems. According to monitoring data, the parameters of the calculation models are adjusted to increase the reliability of the simulation results. A technique is proposed for a preliminary assessment of the displacement of the earth’s surface in the influence zone of the construction of subways tunnels.
Thermomechanical characterization of a low viscosity PA66 thermoplastic matrix and associated continuous glass fibre composite under processing conditions (2019)

Characterizing the thermomechanical properties of thermoplastic resins and associated composites is of outmost importance to understand the development of process-induced stresses. To that extent, the characterization of a low viscosity PA66 matrix is proposed thanks to a homemade volumetric dilatometer named PvT-XT and a dynamic mechanical analyser on a wide temperature range. The PvT-XT results, reported for the first time, permit to identify the evolution of the coefficients of thermal expansion, of crystallization shrinkage and of the bulk modulus with temperature. Dynamic mechanical analyser experiments lead to the estimation of the Young’s modulus. The shear modulus as well as the Poisson’s ratio are then estimated thanks to analytical relations for isotropic and homogeneous materials. These properties are used to feed a new analytical model estimating the coefficients of thermal expansion of quasi-unidirectional composites. All the results are compared with the values from the literature or from complementary experiments, showing a good agreement which permits to validate the developed methodology.
Combining classifiers to identify online databases (2007)

We address the problem of identifying the domain of onlinedatabases. More precisely, given a set F of Web forms automaticallygathered by a focused crawler and an online databasedomain D, our goal is to select from F only the formsthat are entry points to databases in D. Having a set ofWebforms that serve as entry points to similar online databasesis a requirement for many applications and techniques thataim to extract and integrate hidden-Web information, suchas meta-searchers, online database directories, hidden-Webcrawlers, and form-schema matching and merging.We propose a new strategy that automatically and accuratelyclassifies online databases based on features that canbe easily extracted from Web forms. By judiciously partitioningthe space of form features, this strategy allows theuse of simpler classifiers that can be constructed using learningtechniques that are better suited for the features of eachpartition. Experiments using real Web data in a representativeset of domains show that the use of different classifiersleads to high accuracy, precision and recall. This indicatesthat our modular classifier composition provides an effectiveand scalable solution for classifying online databases.
Aesthetic Management of External Skin Paddles Following Microvascular Reconstruction of the Head and Neck (2008)

Microvascular free tissue transfer has become a popular reconstructive option for a wide range of complex head and neck defects. Although highly effective in achieving wound closure, this technique frequently introduces skin paddles with inherent differences in thickness, color, and texture. In resurfacing of cutaneous facial defects, such disparity often leads to inferior aesthetic results. For patients, poor appearance following head and neck reconstruction can become a significant source of distress and add additional burden to their recovery. This article describes several options available in the postoperative setting to improve the appearance of transferred skin paddles. Regional tissue rearrangement with the submental and posterior scalping flaps is discussed in detail.
Study of Local Binary Patterns (2007)

This Masters thesis studies the concept of local binary patterns, which describe the neighbourhood of a pixel in a digital image by binary derivatives. The operator is often used in texture analysis and has been successfully used in facial recognition. This thesis suggests two methods based on some basic ideas of Björn Kruse and studies of literature on the subject. The first suggested method presented is an algorithm which reproduces images from their local binary patterns by a kind of integration of the binary derivatives. This method is a way to prove the preservation of information. The second suggested method is a technique of interpolating missing pixels in a single CCD camera based on local binary patterns and machine learning. The algorithm has shown some very promising results even though in its current form it does not keep up with the best algorithms of today.
Optimization of Switched Linear Systems Over Non-Stationary Wireless Channels (2018)

This paper considers the switched linear system for a series of control systems that are closed over a wireless channel that is unknown and non-stationary. The goal is to find power allocation policies that minimize a long term quadratic cost of all state variables by closing the loop sufficiently often while satisfying a budget constraint. The problem is formulated through duality as a stochastic optimization problem. Because the channel distribution is not know, and empirical risk is solved to approximate the problem. As the channel varies over time, the empirical risk minimization must be continuously approximated. The second order Newton's method is presented as an effective approach to find approximated allocation policies over as the channel varies because of its quadratic convergence and the closeness of consecutive solutions. Under certain conditions on the sampling size and rate of channel variation, we establish a control performance suboptimality for each time epoch and subsequently demonstrate long term stability of the states. We additionally provide a numerical experiment that illustrates the theoretical results.
3D-0D Graphene-Fe3O4 Quantum Dot Hybrids as High-Performance Anode Materials for Sodium-Ion Batteries (2016)

Transition metal oxides can be considered as appealing candidates for sodium ion battery anode materials because these low-cost materials possess high capacity and enhanced safety. However, the practical application of these materials is usually limited by their low electronic conductivity and serious volume change during the charging–discharging process. Herein, we report the fabrication of 3D-0D graphene-Fe3O4 quantum dot hybrids by a facile one-pot hydrothermal approach as anode materials for sodium-ion batteries. Fe3O4 quantum dots with an average size of 4.9 nm are anchored on the surface of 3D structured graphene nanosheets homogeneously. Such unique hierarchical structure are advantageous for enlarging the electrode/electrolyte interface area and enhancing the electrochemical activity of the hybrid materials, inhibiting particle aggregation of Fe3O4 and accommodating their volume change during the charging–discharging process as well as enabling fast diffusion of electrons and rapid transfer of electrolyte ions. Consequently, the 3D-0D graphene-Fe3O4 quantum dot hybrids exhibit ultrahigh sodium storage capacity (525 mAh g–1 at 30 mA g–1), outstanding cycling stability (312 mAh g–1 after 200 cycles at 50 mA g–1) and superior rate performance (56 mAh g–1 at 10 A g–1).
GROWTH HORMONE RELEASING FACTOR AND THE BIOASSAY-RADIOIMMUNOASSAY PARADOX REVISITED (1977)

ABSTRACT Relationships between depletion of growth hormone (GH) from the rat adenohypophysis and its release into the circulation were re-evaluated using bioassay (BA: rat tibia test) and radioimmunoassay (RIA). Anaesthetized male rats were injected with a putative growth hormone releasing factor ("GRF") and killed 15 and 30 min later. For the assays, the plasma and adenohypophyses were pooled; the latter were separated into granule and cytosol fractions prior to assay. Fifteen minutes after "GRF" injection the BA recorded a 75 % depletion of GH from the granular fraction but the RIA measured a loss of only 13 %. By 30 min both assays recorded restoration of pituitary GH. Only slight changes occurred in the levels of BA- or RIA-detectable GH in the cytosol fractions. The massive depletion of bioassayable GH from the granule fraction was accompanied by a large increase (3.2 mU/ml) in the plasma concentration of BA-detectable hormone by 15 min. The slight depletion of RIA-detectable GH that occurred during this time was associated with a meagre increase (0.05 mU/ml) in the plasma level of immunoreactive GH. The plasma concentration of BA- and RIA-detectable GH did not change significantly between 15 and 30 min. Analysis of the relationship between depletion of GH from the pituitary and its release into the extrapituitary compartment disclosed that the BA recordings of these events were in excellent quantitative agreement but RIA measurements were not. The results confirm that biologically active GH can be depleted from and released by the adenohypophysis in vivo independently of RIA-detectable GH.
The method of time-resolved spin-probe oximetry: its application to oxygen consumption by cytochrome c oxidase (1992)

This work broadens the scope and improves the time resolution of spin-probe oximetry, a technique in which small nitroxide spin probes detect oxygen consumption via change in their relaxation properties [Froncisz, W., Lai, C.-S., & Hyde, J. S. (1985) Proc. Natl. Acad. Sci. U.S.A. 82, 411-415]. For rapid oxygen kinetic studies we combined the methodology of spin-probe oximetry with a recently developed loop-gap resonator, stopped-flow EPR system [Hubbell, W. L., Froncisz, W., & Hyde, J. S. (1987) Rev. Sci. Instrum. 58, 1879-1886]. The technique used microliter volumes of reactant solutions. Enzymatic consumption of oxygen by cytochrome c oxidase in the presence of ferrocytochrome c substrate was followed continuously in time under limited-turnover conditions, where the concentration of oxygen consumed often was comparable to or less than the amount of enzyme present. In detecting less than micromolar oxygen concentration changes, we have achieved a time resolution of the order 30 ms when flow is stopped. Oxygen consumption was followed under two different limited-turnover conditions: In the first, the amount of oxygen consumed was limited by available ferrocytochrome c, and the time course of oxygen consumption and its pH dependence were compared with the optically detected ferrocytochrome c consumption. In the second, the oxygen consumed was ultimately limited by the availability of oxygen itself while ferrocytochrome c was regenerated and remained in excess.(ABSTRACT TRUNCATED AT 250 WORDS)
INTRACYCLIC SPEED FLUCTUATIONS OF THE CENTER OF MASS AND ITS RELATIONSHIP WITH THE INDEX OF COORDINATION - A PILOT STUDY (2008)

The purpose of this study was to analyse the relationship between the intracyclic speed fluctuations (dv) of the center of mass (CM), in the x,y,z axes, and the Index of Coordination (IdC), as well as to assess the general stroking parameters during the 200 m front crawl event. A good level male swimmer performed the 200 m front crawl at maximum intensity, being video taped by six cameras (2 above and 4 under the water).
One complete stroke cycle was analysed in each 50 m of the 200 m test, using the APASystem (Ariel Dynamics Inc). IdC appeared to be well related to dv, both in the horizontal and vertical axes. It was also observed, during the 200 m effort, that the IdC, dv, stroke rate and stroke length changed during the exercise.
A Generic Paradigm for Blockchain Design (2018)

Cryptocurrencies have recently gained huge popularity. It is desirable to come up with effective approaches to constructing better blockchain protocols. In this paper, inspired by the 2-hop design by Duong et al (ePrint 2016/716), we put forth a generic paradigm for blockchain design, called n-hop blockchain. It includes one main chain, which is supported by (n -- 1) supporting chains; hence, the main chain can achieve better security performance. In our paradigm, we show that our n-hop design can be easily extended to (n + 1)-hop design. To demonstrate the power of our paradigm, we showcase two instantiations: 2-hop blockchain variant, a combination of proof-of-stake and proof-of-work, and 3-hop blockchain variant, which is extended from 2-hop blockchain variant by adding Byzantine fault tolerance blockchain in 3rd hop.
Refsum's disease: a peroxisomal disorder affecting phytanic acid α‐oxidation (2002)

Refsum's disease (hereditary motor sensory neuropathy type IV, heredopathia atactica polyneuritiformis) is an autosomal recessive disorder the clinical features of which include retinitis pigmentosa, blindness, anosmia, deafness, sensory neuropathy, ataxia and accumulation of phytanic acid in plasma- and lipid-containing tissues. The transport and biochemical pathways of phytanic acid metabolism have recently been defined with the cloning of two key enzymes, phytanoyl-CoA 2-hydroxylase (PAHX) and 2-hydroxyphytanoyl-CoA lyase, together with the confirmation of their localization in peroxisomes. PAHX, an iron(II) and 2-oxoglutarate-dependent oxygenase is located on chromosome 10p13. Mutant forms of PAHX have been shown to be responsible for some, but not all, cases of Refsum's disease. Certain cases have been shown to be atypical mild variants of rhizomelic chondrodysplasia punctata type 1a. Other atypical cases with low-plasma phytanic acid may be caused by alpha-methylacyl-CoA racemase deficiency. A sterol-carrier protein-2 (SCP-2) knockout mouse model shares a similar clinical phenotype to Refsum's disease, but no mutations in SCP-2 have been described to-date in man. This review describes the clinical, biochemical and metabolic features of Refsum's disease and shows how the biochemistry of the alpha-oxidation pathway may be linked to the regulation of metabolic pathways controlled by isoprenoid lipids, involving calcineurin or the peroxisomal proliferator activating alpha-receptor.
Analysis and simulation of the optical spectra of the stoichiometric NdOF (1998)

The UV–VIS–NIR absorption of the rhombohedral NdOF was measured at selected temperatures between 9 and 300 K. The emission spectra of NdOF, LaOF:Nd3+ and GdOF:Nd3+ were obtained at 4.2, 9, 77 and 300 K. The energy level scheme of the Nd3+ ion (the 4 configuration) derived from the optical spectra was simulated with a phenomenological model taking simultaneously into account both the free ion interactions and the crystal field (c.f.) effect for the C3v point symmetry of the Nd3+ site in NdOF. The simulation yielded a good correlation (rms deviation 17 cm-1) between the experimental and calculated energy level schemes of 122 Kramers doublets of a total of 182. The c.f. parameters show only slight distortion from the cubic Oh symmetry. The fourth and sixth rank c.f. effects have an important contribution to the overall c.f. interaction, while the contribution of second rank crystal field is small which indicates an important electrostatic interaction between the cation and anions. A comparison to Pr3+ (4), Sm3+ (4), Eu3+ (4), Tb3+ (4) and Dy3+ (4 electron configuration) in LnOF (Ln=lanthanide) shows a smooth evolution of the c.f. effect.
Multifunctional Fluorescent-Magnetic Polymeric Colloidal Particles: Preparations and Bioanalytical Applications (2015)

Fluorescent-magnetic particles (FMPs) play important roles in modern materials, especially as nanoscale devices in the biomedical field. The interesting features of FMPs are attributed to their dual detection ability, i.e., fluorescent and magnetic modes. Functionalization of FMPs can be performed using several types of polymers, allowing their use in various applications. The synergistic potentials for unique multifunctional, multilevel targeting nanoscale devices as well as combination therapies make them particularly attractive for biomedical applications. However, the synthesis of FMPs is challenging and must be further developed. In this review article, we summarized the most recent representative works on polymer-based FMP systems that have been applied particularly in the bioanalytical field.
Distortion‐free diffusion MRI using an MRI‐guided Tri‐Cobalt 60 radiotherapy system: Sequence verification and preliminary clinical experience (2017)

A diffusion technique with excellent geometric fidelity, accurate, and reproducible ADC measurement was demonstrated for longitudinal tumor response assessment using a low-field MRI-guided radiotherapy system.
Recombinant Baculovirus Isolation (2007)

Although there are several different methods available of making recombinant baculovirus expression vectors (reviewed in Chapter 3), all require a stage in which insect cells are transfected with either the virus genome alone (Bac-to-Bac or BaculoDirect, Invitrogen) or virus genome and transfer vector. In the latter case, this allows the natural process of homologous recombination to transfer the foreign gene, under control of the polyhedrin or other baculovirus gene promoter, from the transfer vector to the virus genome to create the recombinant virus. Additionally, many systems require a plaque-assay to separate parental and recombinant virus prior to amplification and use of the recombinant virus. This chapter provides an overview of the historical development of increasingly more efficient systems for the isolation of recombinant baculoviruses (Chapter 3 provides a full account of the different systems and transfer vectors available). The practical details cover: transfection of insect cells with either virus DNA or virus DNA and plasmid transfer vector; a reliable plaque-assay method that can be used to separate recombinant virus from parental (nonrecombinant) virus where this is necessary; methods for the small-scale amplification of recombinant virus; and subsequent titration by plaque-assay. Methods unique to the Bac-to-Bac system are also covered and include the transformation of bacterial cells and isolation of bacmid DNA ready for transfection of insect cells.
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ChemInform Abstract: Microwave‐Assisted Selenium Dioxide Mediated Selective Oxidation of 1‐Tetralones to 1,2‐Naphthoquinones. (2009)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Induction of Anti-Tumor Immune Responses by Peptide Receptor Radionuclide Therapy with 177Lu-DOTATATE in a Murine Model of a Human Neuroendocrine Tumor (2013)

Peptide receptor radionuclide therapy (PRRT) is a relatively new mode of internally targeted radiotherapy currently in clinical trials. In PRRT, ionizing radioisotopes conjugated to somatostatin analogues are targeted to neuroendocrine tumors (NETs) via somatostatin receptors. Despite promising clinical results, very little is known about the mechanism of tumor control. By using NCI-H727 cells in an in vivo murine xenograft model of human NETs, we showed that (177)Lu-DOTATATE PRRT led to increased infiltration of CD86+ antigen presenting cells into tumor tissue. We also found that following treatment with PRRT, there was significantly increased tumor infiltration by CD49b+/FasL+ NK cells potentially capable of tumor killing. Further investigation into the immunomodulatory effects of PRRT will be essential in improving treatment efficacy.
Early Activation of Inflammation- and Immune Response-Related Genes after Experimental Detachment of the Porcine Retina (2008)

Differentially expressed genes in the retina early after experimental detachment are mainly related to inflammation and immune responses, intracellular proteolysis, and protection against oxidative stress. A local immune and inflammatory response may represent a major causative factor for reactive changes in the retina after detachment. The inflammatory response is not restricted to the detached retina but is also observed in the nondetached retina; this response may underlie functional changes in these regions described in human subjects.
A patient with cerebral Whipple's disease and a stroke-like syndrome (2005)

The central nervous system (CNS) may be affected in up to 50% of patients with Whipple's disease and this can occur even with little or no gastrointestinal involvement. We describe a 63-year-old patient in whom CNS involvement with Whipple's disease had the clinical and imaging features of a brain infarction. Treatment with aspirin and ceftriaxone followed by trimethoprim-sulfamethoxazole resulted in a good neurological recovery and complete remission of the malabsorption syndrome. Cerebral Whipple's disease resembling a stroke syndrome has so far been reported in only two other patients and in both cases it represented the first presentation of the disease. Arterial or arteriolar fibrosis, thrombosis and thickening associated with the inflammation of adjacent brain parenchyma and leptomeninges, and cerebral vasculitis caused by the hematogenous spread of Tropheryma whippelii to the brain may all be important triggers of brain infarction in patients with Whipple's disease. Our case report highlights the important point that cerebral Whipple's disease with the features of a stroke syndrome, if recognized early and treated aggressively with antibiotics, could have a favorable course with no long-term disability sequelae.
Neuropeptide Y signaling modulates the expression of ethanol‐induced behavioral sensitization in mice (2011)

Neuropeptide Y (NPY) and protein kinase A (PKA) have been implicated in neurobiological responses to ethanol. We have previously reported that mutant mice lacking normal production of the RIIβ subunit of PKA (RIIβ-/- mice) show enhanced sensitivity to the locomotor stimulant effects of ethanol and increased behavioral sensitization relative to littermate wild-type RIIβ+/+ mice. We now report that RIIβ-/- mice also show increased NPY immunoreactivity in the nucleus accumbens (NAc) core and the ventral striatum relative to RIIβ+/+ mice. These observations suggest that elevated NPY signaling in the NAc and/or striatum may contribute to the increased sensitivity to ethanol-induced behavioral sensitization that is a characteristic of RIIβ-/- mice. Consistently, NPY-/- mice failed to display ethanol-induced behavioral sensitization that was evident in littermate NPY+/+ mice. To examine more directly the role of NPY in the locomotor stimulant effects of ethanol, we infused a recombinant adeno-associated virus (rAAV) into the region of the NAc core of DBA/2J mice. The rAAV-fibronectin (FIB)-NPY(13-36) vector expresses and constitutively secretes the NPY fragment NPY(13-36) (a selective Y(2) receptor agonist) from infected cells in vivo. Mice treated with the rAAV-FIB-NPY(13-36) vector exhibited reduced expression of ethanol-induced behavioral sensitization compared with mice treated with a control vector. Taken together, the current data provide the first evidence that NPY signaling in the NAc core and the Y(2) receptor modulate ethanol-induced behavioral sensitization.