gebhart/patrepeval huggingface dataset:
Specificity of bacterial ribosomes and messenger ribonucleic acids in protein synthesis reactions in vitro. (1976)

Ribosomes from two Gram-negative bacteria translated f2 RNA, T4 early mRNA, mRNA from three Gran-negative bacteria, and mRNA from six Gram-positive bacteria; ribosomes from three Gram-positive bacteria translated mRNA from the Gram-positive strains, but did not translate the other mRNAs. Ribosomes from the Gram-negative bacterium Escherichia coli translated synthetic poly(U,G) but ribosomes from the Gram-positive bacterium Clostridium pasteurianum translated poly(U,G) very poorly, mRNA from Gram-negative bacteria was translated only in the presence of a high salt ribosomal wash containing initiation factors. mRNA from Gram-positive bacteria and synthetic poly(U,G) were translated much more efficiently when wash components were present, but were also translated to a small, but significant, extent in the absence of wash components. The translation specificity of each type of ribosome was independent of the source of ribosomal wash components. When the radioactively labeled products of in vitro protein synthesis were analyzed by sodium dodecyl sulfate-polyacrylamide slab gel electrophoresis and autoradiography, it was found that each different bacterial and phage RNA preparation directed the synthesis of a unique set of polypeptide products of discrete sizes. Three different types of ribosomes were used to translate each of several Gram-positive bacterial messenger preparations; the overall patterns of products obtained with a given mRNA are similar, but some differences in the products formed or the relative amounts of the various products synthesized can be detected.
Quality control of red cell filtration at the patient's bedside (1994)

The RBC filtration at the patient's bedside can be equal in quality to that performed in the laboratory, at least in such clinical settings as hematology and oncology departments in which blood transfusion is common practice, and if simple training is provided to the nursing staff. Under the conditions of this study, it seems that quality control of RBC bedside filtration is feasible and simple.
The Effect of Chemical Environment on Swelling and Dynamic Mechanical Properties of Milled Wood Lignin Gels (1988)

Influence du pH et de la concentration de l'electrolyte (NaCl) sur le gonflement et les proprietes dynamomecaniques
Placement of energy storage coordinated with smart PV inverters (2012)

Energy storage (ES) is increasing used in electrical transmission and distribution systems because it can perform many functions. These include peak shaving, voltage regulation, frequency regulation, spinning reserve, and aiding integration of renewable generation by mitigating the effects of intermittency. This work focuses on the usage of energy storage for peak shaving and voltage regulation on a distribution system having a high penetration of photovoltaic (PV) generation. The PV stations considered make use of smart PV inverters as proposed by the Electric Power Research Institute (EPRI). These inverters assist the energy storage with voltage regulation. Additionally, the proposed method includes support for varying energy storage unit (ESU) sizes, non-radial distribution systems, and reverse power flow, both real and reactive. The method is applied to the worst-case voltage regulation scenario. The impact of the placement and voltage regulation on the profitability of energy storage is assessed. This is accomplished by adding voltage regulation as a constraint to the problem scheduling energy storage in order to maximize profit. Applying the method shows that the best place to put an ESU is near the end of a feeder. Validation of the method shows that it does not impact the ability of ES to be scheduled in order to maximize economic benefits with time-of-use pricing.
<title>Holographic antireflection coatings</title> (1998)

Using holographic methods to fabricate antireflection coatings is attractive because arbitrarily small reflectivities may be achieved at a single wavelength with a simple photographic process. In this paper, we discuss the theoretical aspects of these holograms and the technical aspects of fabricating them. We present numerical simulations that predict the spectral response of the coating as a function of the bandwidth of the recording source and the thickness and modulation of the emulsion. These results are confirmed with spectrophotometer measurements of actual coatings. Recording holographic antireflection coatings requires a single collimated light source. The hologram-air interface is sued to create the second wave; this allows the coating to automatically correct for variation in the surface of the hologram. However, this method requires a post recording coating procedure to produce a diffracted wave with the correct phase shift. After the hologram is recorded and processed, a thin layer of SiO<SUB>2</SUB> or MgF<SUB>2</SUB> is applied to the hologram to adjust the phase shift between the diffracted wave and the surface reflection. Additionally this coating procedure enhances the durability of the coating and, if MgF<SUB>2</SUB> is used, lowers the refractive index modulation required for complete cancellation of the surface reflection.
Laminectomy alone versus fusion for grade 1 lumbar spondylolisthesis in 426 patients from the prospective Quality Outcomes Database (2019)

OBJECTIVEThe AANS launched the Quality Outcomes Database (QOD), a prospective longitudinal registry that includes demographic, clinical, and patient-reported outcome (PRO) data to measure the safety and quality of spine surgery. Registry data offer "real-world" insights into the utility of spinal fusion and decompression surgery for lumbar spondylolisthesis. Using the QOD, the authors compared the initial 12-month outcome data for patients undergoing fusion and those undergoing laminectomy alone for grade 1 degenerative lumbar spondylolisthesis.METHODSData from 12 top enrolling sites were analyzed and 426 patients undergoing elective single-level spine surgery for degenerative grade 1 lumbar spondylolisthesis were found. Baseline, 3-month, and 12-month follow-up data were collected and compared, including baseline clinical characteristics, readmission rates, reoperation rates, and PROs. The PROs included Oswestry Disability Index (ODI), back and leg pain numeric rating scale (NRS) scores, and EuroQol-5 Dimensions health survey (EQ-5D) results.RESULTSA total of 342 (80.3%) patients underwent fusion, with the remaining 84 (19.7%) undergoing decompression alone. The fusion cohort was younger (60.7 vs 69.9 years, p < 0.001), had a higher mean body mass index (31.0 vs 28.4, p < 0.001), and had a greater proportion of patients with back pain as a major component of their initial presentation (88.0% vs 60.7%, p < 0.001). There were no differences in 12-month reoperation rate (4.4% vs 6.0%, p = 0.93) and 3-month readmission rates (3.5% vs 1.2%, p = 0.45). At 12 months, both cohorts improved significantly with regard to ODI, NRS back and leg pain, and EQ-5D (p < 0.001, all comparisons). In adjusted analysis, fusion procedures were associated with superior 12-month ODI (β -4.79, 95% CI -9.28 to -0.31; p = 0.04).CONCLUSIONSSurgery for grade 1 lumbar spondylolisthesis-regardless of treatment strategy-was associated with significant improvements in disability, back and leg pain, and quality of life at 12 months. When adjusting for covariates, fusion surgery was associated with superior ODI at 12 months. Although fusion procedures were associated with a lower rate of reoperation, there was no statistically significant difference at 12 months. Further study must be undertaken to assess the durability of either surgical strategy in longer-term follow-up.
X-ray crystal and molecular structure of tris(N,N-diethyldithiocarbamato)-bis[.mu.-(N,N-diethyltrithiocarbamato)]-diosmium(III) tetraphenylborate. The first example of a sulfur-rich dithiocarbamate (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleX-ray crystal and molecular structure of tris(N,N-diethyldithiocarbamato)-bis[.mu.-(N,N-diethyltrithiocarbamato)]-diosmium(III) tetraphenylborate. The first example of a sulfur-rich dithiocarbamateL. J. Maheu and L. H. PignoletCite this: Inorg. Chem. 1979, 18, 12, 3626–3629Publication Date (Print):December 1, 1979Publication History Published online1 May 2002Published inissue 1 December 1979https://pubs.acs.org/doi/10.1021/ic50202a073https://doi.org/10.1021/ic50202a073research-articleACS PublicationsRequest reuse permissionsArticle Views53Altmetric-Citations18LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Allosteric agonists of the calcium receptor (CaR): fluorine and SF5 analogues of cinacalcet (2012)

Three selectively fluorinated cinacalcet analogues are prepared and their activity as calcium-sensing receptor (CaR) agonists is assessed. Individual (2R,1'R)-2 and (2S,1'R)-3 fluorocinacalcet diastereoisomers were prepared using the MacMillan asymmetric fluorination reaction. Assays with the recombinant human CaR revealed that both diastereoisomers have a similar potency to each other although slightly lower (75-80%) than that of cinacalcet 1. The SF(5)-cinacalcet analogue 4 was prepared from meta-pentafluorosulfanyl benzyl alcohol and has ~75% agonist activity relative to cinacalcet 1 indicating that the SF(5) group can replace the CF(3) group and retain significant bioactivity.
Effect of <i>CTLA4</i> gene polymorphism on relapse probability among patients with acute leukemias after allogenic hematopoietic stem cells transplantation (2019)

Background. Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is being widely applied as a therapy for hematological malignancies. The long-term outcome of allo-HSCT depends directly on the ability of cytotoxic T-lymphocytes to recognize and eliminate the residual tumor. CTLA-4 is one of the regulatory proteins that provide control over the development of the immune response. Polymorphisms in the CTLA4 gene can affect its function and the efficiency of the antitumor response. The objective: to study the effect of non-synonymous single nucleotide polymorphism (nsSNP) c.49AG in the donor CTLA4 gene on tumor control in the recipient of allogeneic hematopoietic stem cells (HSC). Materials and methods. Donors of HSC were genotyped for nsSNP c.49AG in the CTLA4 gene by the real-time polymerase chain reaction using the allele-specific primers. Genotyping data was validated by Sanger’s sequencing of 22 randomly selected samples. The overall survival, the event-free survival and relapse probability were calculated using the Kaplan–Mayer method. A log-rank test was used to assess the statistical significance of group disparities. A p-value of 0.05 was considered as significant. Results. The frequencies of the CTLA4 gene c.49AG polymorphism alleles in the observed population (102 healthy donors of HSC) correspond to the frequencies obtained by the “1000 genomes” project for the European population. The effect of the donor CTLA4 polymorphism on the tumor control was evaluated on the cohort of patients with acute leukemia after human leukocyte antigen (HLA) matched HSCT from an unrelated donor. It was shown, the three-year relapse-free survival was significantly lower for those patients who received grafts from a donor with the homozygous A/A state of nsSNP c.49AG (p = 0.01), it was 12.7 % versus 62,8 % in group with c.49AG G/G and A/G donor genotypes. The incidence of relapse was also significantly different for the group with A/A genotype and for the group with G/G or A/G genotypes of the nsSNP and equaled to 83.7 and 29.3 % respectively (p = 0.03). Conclusion. Patients with acute leukemia, who underwent allo-HSCT from unrelated completely HLA-matched donors with c.49AG G/G or A/G genotypes have the significantly lower risk of relapse than patients whose donors had the A/A genotype. These results suggest practicability of the nsSNP genotyping for the optimal donor selection.
[Multihormonal bilateral petrosal sinus sampling in Cushing's disease: radiological, surgical and pathological correlations]. (2002)

Multihormonal bilateral petrosal sinus sampling (BPSS) has been proposed to improve corticotroph microadenomas prediction of lateralisation. Few series have simultaneously compared data of pituitary MRI, surgical findings and multihormonal BPSS. Seven patients (6F/1M) with Cushing's disease, mean age at diagnosis of 35 years (range 24-55) were prospectively studied to compare radiological and multihormonal BPSS data with surgical and pathological findings. In untreated patients, simultaneous measures of ACTH, TSH and prolactine (PRL) were done at time 0, 7, 15, 22 minutes after CRH (500 microgram) and TRH (200 microgram) stimulation. An intersinus gradient of 1.4 was considered as a lateralisation. All microadenomas were identified during surgery, diameters ranged from 2 to 7 mm. All patients were in long-term surgical remission. Pathological studies confirmed a tumoral tissue with ACTH immunostaining in 6/7 cases and PRL in 3/7 cases. Pituitary MRI correctly identified tumors in 4 cases, the remaining tumors were not seen. Basal and stimulated intersinus gradients of ACTH, TSH and PRL were homolateral in 6/7 cases and were coincident with surgical findings in 4/7 cases. The other three cases were contralateral to MRI and surgical data. In conclusion, simultaneous gradient of ACTH, PRL and TSH did not improve lateralisation prediction in this series. Hormonal hypersecretion was homolateral in six cases whereas pathological studies demonstrated a mixed secretion in only three cases. A preferential pituitary draining could explain these discordances. Data from our series and from others (done with CRH stimulation and ACTH-PRL measures) strongly suggest a paracrine interaction between tumoral and normal pituitary tissue.
Local Structure Heterogeneity in Sm-Doped AgNbO3 for Improved Energy-Storage Performance (2020)

AgNbO<sub>3</sub>-based antiferroelectric ceramics have been actively studied for energy-storage applications, where numerous compositional modifications have been implemented to improve their energy-storage performance. In this work, Sm<sub>2</sub>O<sub>3</sub>-doped AgNbO<sub>3</sub> ceramics were fabricated; the microstructure, dielectric property, and phase transition behavior were investigated. Because of the structure heterogeneity induced by the rare-earth dopant, a diffused antiferroelectric-to-paraelectric phase transition was observed. High-resolution transmission electron microscopy observations confirm the existence of a local pseudo-rhombohedral structure consisting of different lattice orderings, being responsible for the local nanoscale heterogeneity. Of particular significance is the fact that the Sm<sup>3+</sup> dopant effectively decreases the dielectric loss and increases the critical antiferroelectric-ferroelectric phase transition electric field, leading to a high energy-storage density of 4.5 J/cm<sup>3</sup>.
Chemical Genetic Approaches to Plant Biology (2003)

Synthetic chemistry and plant biology intersect in myriad ways. To date, however, the overlap of research methods between these two fields is limited. Outside of the agrochemical industry, most synthetic chemists simply view plants as sources of diverse and structurally complex organic molecules (i.
A Ti:Al/sub 2/O/sub 3/ master-oscillator/power-amplifier system (1993)

The authors have constructed a multistage Ti:Al/sub 2/O/sub 3/ master-oscillator/power-amplifier system which generates 115-ns, 0.38-J pulses at 800 nm. The system is tunable from 760 to 825 nm and has a repetition rate of 10 Hz. Measurements of the output pulse demonstrate near-diffraction-limited performance and a Fourier-transform-limited bandwidth of approximately 4 MHz.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Case Studies for Teaching Library Management (2013)

Teaching and practice, unfortunately, are two different streams in Indian librarianship and they meet quite rarely. With an exception of a few, most teachers of LIS have no option than borrowing case studies from others' experiences for presenting to their students, if at all they wish to do so. Well articulated true-to-life case studies are not easily and readily available. Here is a book which very effectively fills this gap and probably the first of its kind to provide a number of well thought out case studies of library management. The book has 39 case studies, a brief introduction to library management, 'case analysis' for the first two cases and 'suggested discussion leads' for the remaining cases.
A Position‐Space View on Chemical Bonding in Metal Diborides with AlB2Type of Crystal Structure (2013)

Abstract On the basis of QTAIM and ELI‐D partitioning of position space two‐ and three‐center delocalization indices were calculated for fifteen M B 2 phases with the crystal structure of AlB 2 type. The bonding picture in main‐group metal diborides is closest related to graphite with dominant covalent B–B bonding, albeit with lower effective bond order. For MgB 2 an exceptionally large distant electron sharing was found. Transition‐metal diborides display smaller effective bond orders B–B but higher effective bond orders TM –B and TM – TM than main‐group metal diborides. The large chemical flexibility of this structure type is caused by counterbalancing effects of B–B bonding vs. M –B and M – M bonding. Different three‐center fluctuation channels of bonds B–B are found for main‐group and transition‐metal diborides, namely B–B–B for the former and B–B– M for the latter. With the technique of ELI‐D/QTAIM intersection the increasing importance of B 2 →4 M bond charge fluctuations along each row of the periodic table can be recovered already at the topological level of analysis.
A Comparative Study of Adaptive Soft Sensors for Quality Prediction in an Industrial Refining Hydrocracking Process (2018)

Soft sensors have played indispensable roles in modern refining industry, which can provide significant information for process modeling, control, monitoring and optimization. However, the prediction performance often gradually deteriorates due to process time-varying problem caused by reasons like catalyst deactivation. Therefore, it is very important to update the inferential models regularly in order to keep good prediction performance. In this paper, a comparative study of adaptive soft sensors is carried out for quality prediction in a real hydrocracking process. Recursive partial least squares (RPLS), moving window RPLS (MWRPLS), locally weighted partial least squares (LWPLS) and moving window LWPLS (MWLWPLS) models are built to predict the 10% boiling point of the aviation kerosene product. The results show that RPLS and MWRPLS can provide better prediction performance.
Protein can act as unique template to assemble gold nanoparticles in a linear fashion. (2006)

Nanoparticles of metals possess unique chemical, electronic, optical and magnetic properties that differ from their bulk counterpart because of the quantum size effects [14] . The spatial orientation and arrangement of nanoparticles is important in the realization of technologically useful nanoparticle-based materials [5-7] . Nevertheless, the assembly of nanoparticles into defined arrays remains a challenge. There are numerous reports of assembly of gold nanoparticles in a defined manner. In most of them, linker molecules were generally added to a preformed gold nanoparticle solution for assembly. Here a facile process for the assembly gold nanoparticles in a linear fashion has been described using protein as templates. The presence of proteins during the reduction of gold salts by sodium borohydride directs the assembly of gold nanoparticles in a linear fashion when cooled to ‐80 0 C followed by thawing at room temperature. Similar results were obtained by cooling at ‐20 0 C, whereas no assembly was observed when cooled at 0 0 C. Assembly was also not observed when proteins were added to gold nanoparticle solution. Therefore, interaction of gold salts with the protein before the reduction is essential for such an assembly process. The assembled products thus obtained were characterized using transmission electron microscopy (TEM), UV-visible spectroscopy (UV-Vis) and thermogravimetric analysis (TGA).
Rhodium‐Catalyzed Ketone Methylation Using Methanol Under Mild Conditions: Formation of α‐Branched Products (2013)

The rhodium-catalyzed methylation of ketones has been accomplished using methanol as the methylating agent and the hydrogen-borrowing method. The sequence is notable for the relatively low temperatures that are required and for the ability of the reaction system to form α-branched products with ease. Doubly alkylated ketones can be prepared from methyl ketones and two different alcohols by using a sequential one-pot iridium- and rhodium-catalyzed process.
Supplementary Figure 3 from BRCA1 Ubiquitinates RPB8 in Response to DNA Damage (2023)

Supplementary Figure 3 from BRCA1 Ubiquitinates RPB8 in Response to DNA Damage
A Day-ahead Scheduling Optimization Model of Multi-Microgrid Considering Interactive Power Control (2019)

Aiming at the problem of insufficient stability and security considerations for multi-microgrid system access distribution network, this paper proposes a multi-microgrid day-ahead scheduling optimization model considering interactive power control. The upper optimization model aims to reduce the interaction power between the microgrid and the distribution network and coordinates the output between the microgrids. The lower optimization model is devoted to solve the economic optimization operation of the multi-microgrid system. The bilateral bidding strategy is adopted to make the microgrid conduct energy trading to reduce the overall cost of the multi-microgrid system and reduce the impact of power fluctuations on the distribution network. The distribution network system with multiple microgrids is used to verify that the optimization model can obtain better output plans for each microgrid. The set trading strategy encourages effectively the mutual energy between the microgrids and reduces the micro-grid's impact of grid operation on the distribution network.