gebhart/patrepeval huggingface dataset:
A Maximum Entropy Model of the Distribution of Dengue Serotype in Mexico (2023)

Pathogen strain diversity is an important driver of the trajectory of epidemics. The role of bioclimatic factors on the spatial distribution of dengue virus (DENV) serotypes has, however, not been previously studied. Hence, we developed municipality-scale environmental suitability maps for the four dengue virus serotypes using maximum entropy modeling. We fit climatic variables to municipality presence records from 2012 to 2020 in Mexico. Bioclimatic variables were explored for their environmental suitability to different DENV serotypes, and the different distributions were visualized using three cutoff probabilities representing 90%, 95%, and 99% sensitivity. Municipality-level results were then mapped in ArcGIS. The overall accuracy for the predictive models was 0.69, 0.68, 0.75, and 0.72 for DENV-1, DENV-2, DENV-3, and DENV-4, respectively. Important predictors of all DENV serotypes were the growing degree days for December, January, and February, which are an indicator of higher temperatures and the precipitation of the wettest month. The minimum temperature of the coldest month between -5°C and 20°C was found to be suitable for DENV-1 and DENV-2 serotypes. Respectively, above 700-900 mm of rainfall, the suitability for DENV-1 and DENV-2 begins to decline, while higher humidity still favors DENV-3 and DENV-4. The sensitivity concerning the suitability map was developed for Mexico. DENV-1, DENV-2, DENV-3, and DENV-4 serotypes will be found more commonly in the municipalities classified as suitable based on their respective sensitivity of 91%, 90%, 89%, and 85% in Mexico. As the microclimates continue to change, specific bioclimatic indices may be used to monitor potential changes in DENV serotype distribution. The suitability for DENV-1 and DENV-2 is expected to increase in areas with lower minimum temperature ranges, while DENV-3 and DENV-4 will likely increase in areas that experience higher humidity. Ongoing surveillance of municipalities with predicted suitability of 89% and 85% should be expanded to account for the accurate DENV serotype prevalence and association between bioclimatic parameters.
Application of dip moveout by fourier transform: Method overview and presentation of processed data from 2‐D and 3‐D surveys (1984)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 1984Application of dip moveout by fourier transform: Method overview and presentation of processed data from 2‐D and 3‐D surveysAuthors: Lars E. BergLars E. BergGECO A. S, Norwayhttps://doi.org/10.1190/1.1894244 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1894244FiguresReferencesRelatedDetails SEG Technical Program Expanded Abstracts 1984ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 1984 Pages: 856 publication data© 1984 Copyright © 1984 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished: 24 Mar 2005 CITATION INFORMATION Lars E. Berg, (1984), "Application of dip moveout by fourier transform: Method overview and presentation of processed data from 2‐D and 3‐D surveys," SEG Technical Program Expanded Abstracts : 796-799. https://doi.org/10.1190/1.1894244 Plain-Language Summary PDF DownloadLoading ...
Analysis of Intracellular Distribution of Borna Disease Virus Glycoprotein Fused with Fluorescent Markers in Living Cells (2011)

Borna disease virus (BDV) is a non-segmented, negative-strand RNA virus that is characterized by nuclear replication and persistent infection. A unique feature of BDV is that it releases only a small number of infectious particles from infected cells. Although these characteristics might make it difficult to obtain a large amount of recombinant viruses in a reverse genetics system, the mechanism underlying the budding or assembly of BDV particle has remained largely unknown. In this study, as a first step toward understanding the virion formation of BDV, we investigated the intracellular distribution and mobility of the fluorescent marker fusion envelope glycoprotein (G) of BDV in living cells. Expression analysis revealed that fusion proteins seem to cleave into functional subunits and localize in the endoplasmic reticulum (ER)/Golgi apparatus, as well as the authentic BDV G. Furthermore, we demonstrated using fluorescence recovery after photobleaching analysis that BDV G fluorescence shows rapid recovery in both the ER/Golgi and plasma membrane regions, indicating that BDV G fusion protein may be a useful tool to investigate not only the maturation of BDV G but also the budding and assembly of BDV particles in living cells.
Effects of Candesartan for Middle-Aged and Elderly Women with Hypertension and Menopausal-Like Symptoms (2006)

Hypertension in middle-aged or elderly women is often accompanied with various symptoms, which may be related to climacteric. The symptoms of post-menopausal women are suggested to be derived in part from instability of the sympathetic nerve system due to a low estrogen state. An angiotensin-receptor blocker, candesartan cilexetil (candesartan), is known to suppress sympathetic nerve activity by inhibiting the renin-angiotensin system in the brain, suggesting that it may be effective for ameliorating these symptoms. The aim of this study was to elucidate whether candesartan improves menopausal symptoms in hypertensive women. A total of 69 female patients, aged 40 years or older, who had hypertension and various menopausal-like symptoms, were recruited from 39 centers to participate in this study. Patients were prescribed candesartan 4 to 8 mg/day (average dose 7.2 mg/day), alone or in addition to current antihypertensive medications. We interviewed patients in regard to their menopausal symptoms and scored them using the Simplified Menopausal Index (SMI). During the 12-month observation period, significant decreases were seen in both blood pressure (157+/-21/85+/-11 to 141+/-18/77+/-12 mmHg, p<0.001) and SMI (29+/-18 to 18+/-7, p<0.001), although the heart rate did not change. The percentage of decrease in SMI was correlated with that in systolic blood pressure (r=0.43, p<0.001). Candesartan may be an effective antihypertensive agent to relieve menopausal-like symptoms in middle-aged or elderly hypertensive women.
Weighted Poisson--Delaunay Mosaics (2020)

Slicing a Voronoi tessellation in ${R}^n$ with a $k$-plane gives a $k$-dimensional weighted Voronoi tessellation, also known as a power diagram or Laguerre tessellation. Mapping every simplex of the dual weighted Delaunay mosaic to the radius of the smallest empty circumscribed sphere whose center lies in the $k$-plane gives a generalized discrete Morse function. Assuming the Voronoi tessellation is generated by a Poisson point process in ${R}^n$, we study the expected number of simplices in the $k$-dimensional weighted Delaunay mosaic as well as the expected number of intervals of the Morse function, both as functions of a radius threshold. As a by-product, we obtain a new proof for the expected number of connected components (clumps) in a line section of a circular Boolean model in ${R}^n$.
Enantioselective Synthesis of Nα-Fmoc Protected (2S,3R)-3-Phenylpipecolic Acid. A Constrained Phenylalanine Analogue Suitably Protected for Solid-Phase Peptide Synthesis (2002)

Reported herein is the first enantioselective preparation of (2S,3R)-3-phenylpipecolic acid as a conformationally constrained phenylalanine analogue bearing N(alpha)-protection suitable for solid-phase peptide synthesis. Stereochemistries at both the 2- and 3-positions are derived inductively from a single chiral center provided by the commercially available Evans chiral auxiliary, (4S)-4-benzyl-1,3-oxazolidin-2-one. By constraining phi and chi(1) torsion angles, this novel amino acid analogue can serve as a useful tool for the induction of defined geometry in phenylalanine-containing peptides.
Photocrosslinking of functionalized rubber. II. Photoinitiated cationic polymerization of epoxidized liquid natural rubber (1995)

Abstract Low molecular weight epoxidized natural rubber has been crosslinked within seconds by UV irradiation in the presence of a triarylsulfonium salt. The photoinitiated cationic ring‐opening polymerization was studied quantitatively by infrared spectroscopy and shown to proceed with surprisingly long kinetic chains in such solid medium. The high conversion (60%) needed for complete insolubilization, together with the presence of tetrahydrofuran structures, argue in favor of an intramolecular polymerization process involving neighboring epoxy groups. The photoinitiator concentration has a strong influence on the rate and extent of the reaction, as well as on the depth of cure profile. Because of an efficient dark process, close to 100% conversion was reached upon storage of the irradiated elastomer at ambient, with a concomitant increase of the gel fraction and the polymer hardness. The grafting of pendent acrylate groups onto the polymer chain leads to a three‐fold decrease of the initial rate of polymerization of the epoxide. The photocuring of natural rubber bearing both epoxy and acrylate groups generates a dual polymer network which combines the properties of the two moieties. © 1995 John Wiley &amp; Sons, Inc.
Assessment of a three-dimensional line-of-response probability density function system matrix for PET (2012)

To achieve optimal PET image reconstruction through better system modeling, we developed a system matrix that is based on the probability density function for each line of response (LOR-PDF). The LOR-PDFs are grouped by LOR-to-detector incident angles to form a highly compact system matrix. The system matrix was implemented in the MOLAR list mode reconstruction algorithm for a small animal PET scanner. The impact of LOR-PDF on reconstructed image quality was assessed qualitatively as well as quantitatively in terms of contrast recovery coefficient (CRC) and coefficient of variance (COV), and its performance was compared with a fixed Gaussian (iso-Gaussian) line spread function. The LOR-PDFs of three coincidence signal emitting sources, (1) ideal positron emitter that emits perfect back-to-back γ rays (γγ) in air; (2) fluorine-18 (¹⁸F) nuclide in water; and (3) oxygen-15 (¹⁵O) nuclide in water, were derived, and assessed with simulated and experimental phantom data. The derived LOR-PDFs showed anisotropic and asymmetric characteristics dependent on LOR-detector angle, coincidence emitting source, and the medium, consistent with common PET physical principles. The comparison of the iso-Gaussian function and LOR-PDF showed that: (1) without positron range and acollinearity effects, the LOR-PDF achieved better or similar trade-offs of contrast recovery and noise for objects of 4 mm radius or larger, and this advantage extended to smaller objects (e.g. 2 mm radius sphere, 0.6 mm radius hot-rods) at higher iteration numbers; and (2) with positron range and acollinearity effects, the iso-Gaussian achieved similar or better resolution recovery depending on the significance of positron range effect. We conclude that the 3D LOR-PDF approach is an effective method to generate an accurate and compact system matrix. However, when used directly in expectation-maximization based list-mode iterative reconstruction algorithms such as MOLAR, its superiority is not clear. For this application, using an iso-Gaussian function in MOLAR is a simple but effective technique for PET reconstruction.
Математическая обработка результатов экспериментов по ультразвуковому воздействию на вязкость нефти (2012)

Presented the results of experimental research on the cavitation treatment of high-viscosity oil in order to reduce its dynamic viscosity on the laboratory setup and the results of their mathematical processing.
An iterative approach for estimating the sound speed and attenuation constant of air in a standing wave tube (2022)

In the present work, an iterative method based on the four-microphone transfer matrix approach was developed for evaluating the sound speed and attenuation constant of air within a standing wave tube. In particular, when the air inside the standing wave tube is treated as the material under test, i.e., as if it were a sample of porous material, the transfer matrix approach can be used to identify the air’s acoustic properties. Note that the wavenumber within the tube is complex owing to the formation of a visco-thermal boundary layer on the inner circumference of the tube. Starting from an assumed prior knowledge of the air properties, an iterative method can be applied in the post-processing stage to estimate the complex wavenumber accurately. Experimental results presented here show that although the results are sensitive to ambient temperature, a formula previously proposed by Temkin matches closely with the measured sound speed and attenuation constant. Furthermore, it is shown that the Temkin prediction accurately represents the variation of sound speed with frequency, in contrast to the formula recommended in the ASTM E1050 standard, in which the sound speed is assumed to be independent of frequency.
Synthesis and Reactivity of New Silylated Sulfur‐Containing Heterocycles Through Thionation of Bis(acylsilanes) (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
Electrical impedance tomography in perioperative medicine: careful respiratory monitoring for tailored interventions (2019)

EIT is a promising technique for the perioperative assessment of surgical patients, providing tailored adaptive respiratory and haemodynamic monitoring. Further studies are needed to address the current technological limitations, confirm the findings and evaluate which patients can benefit more from this technology.
An Alternate Aircraft Propulsion Technique (2012)

The underlying paper presents the use of lasers in aircraft engines for combustion. The proposed theoretical model of an aircraft engine uses laser as a source to ignite fuel and thereby imparting propulsive power to the aircraft. Lasers being a promising source of energy provide an option of complete and uniform heating of the air-fuel mixture which ensure complete and clean combustion of fuel. Main emphasis for conceptualization of this paper is to make aircraft industry greener. Therefore, laser guns as an ignition source also demonstrate a unique property of sterilizing the air that passes through its path. So, the air available for combustion is free from organic substances and exhaust formed will be less polluting as compared to conventional engine exhausts. Some of the research works that have been completed do exhibit very promising results, which will be discussed in upcoming sections. Keywords: Aircraft propulsion technique, laser technology, aircraft fuel
Expression of cytoadhesion molecules (CD56, CD54, CD18 and CD29) by myeloma plasma cells (1991)

Recently we reported the expression of the human natural killer cell associated antigen CD56 (Leu 19/NKH1) in plasma cells of a majority of multiple myeloma (MM) patients. CD56 is known to be an isoform of the human neural adhesion molecule N-CAM which is involved in homotypic adhesive interactions. By immunophenotyping using four CD56 specific monoclonal antibodies and immunoprecipitation analysis we here confirm that the Leu 19 antigen expressed by myeloma plasma cells is identical to N-CAM and corresponds to the 145 kDa isoform. Because of the possible biological role of adhesion molecules on myeloma cells, we compared the expression of N-CAM with the intercellular adhesion molecule 1 (ICAM-1) and the beta 1 and beta 2 integrins. By immunogold-silver staining of cytospin preparations of mononuclear cell suspensions, bone marrow plasma cells of 17 MM patients were analysed. Plasma cells expressed N-CAM (CD56) in 14 patients. ICAM-1 (CD54) in 16 patients, and beta 2 integrins (CD18) in eight patients. beta 1 integrins (CD29) were expressed in all patients. The expression of beta 2 integrins was always very weak while N-CAM, ICAM-1 and the beta 1 integrins showed a moderate to strong positivity. The plasma cells of five haematological normal individuals lacked significant N-CAM expression but were positive for ICAM-1 and both integrin subgroups. One plasma cell leukaemia patient and two out of four end-stage MM patients showed no expression of N-CAM or beta 2 integrins on their circulating plasma cells. Among 11 previously established myeloma cell lines, surface expression of ICAM-1 and the integrins was detected in most cases, while N-CAM was present in only four lines. Most cell lines showed coexpression of the fibronectin receptors (VLA-4 and VLA-5) and the laminin receptor (VLA-6). The collagen receptor (VLA-2) was not expressed. The N-CAM negative cell lines included four cell lines that were derived from plasma cell leukaemia patients. These results indicate that the expression of adhesion molecules is an intrinsic part of the biology of multiple myeloma.
Body and objects representations are associated with similar distortions (2014)

Stored representations of body size and shape as derived from somatosensation (body model) are considered to be critical components of perception and action. It is commonly believed that the body model can be measured using a localization task and be distinguished from other visual representations of the body using a visual template matching task. Specifically, localization tasks have shown distorted hand representations consisting of an overestimation of hand width and an underestimation of finger length [Longo and Haggard, 2010, PNAS,107 (26), 11727-11732]. In contrast, template matching tasks indicate that visual hand representations (body image) do not show such distortions [Longo and Haggard, 2012, Acta Psychologica, 141, 164-168]. We examined the specificity of the localization and visual template matching tasks to measure body related representations. Participants conducted a localization and template matching task with objects (box, post-it, rake) and their own hand. The localization task revealed that all items' dimensions were significantly distorted (all p <.0018) except for the width of the hand and rake. In contrast, the template matching task indicated no significant differences between the estimated and actual item's shape for all items (all p>0.05) except for the box (p<0.01) suggesting that the visual representation of items is almost veridical. Moreover, the performance across these tasks was significantly correlated for the hand and rake (p<.001). Overall, these results show that effects considered to be body-specific, i.e. distortions of the body model, are actually more general than previously thought as they are also observed with objects. Because localizing points on an object is unlikely to be aided by somatosensation, the assessed representations are unlikely to be mainly based on somatosensation but might reflect more general cognitive processes e.g. visual memory. These findings have important implications for the nature of the body image and the body model. Meeting abstract presented at VSS 2014
Mode-expanded semiconductor laser with tapered-rib adiabatic-following fiber coupler (1996)

Expanded-mode semiconductor lasers are of great interest due to the benefits of reduced far-field divergence and improved coupling efficiency to optical fiber. The authors present a new diode laser using a Tapered-Rib Adiabatic-Following Fiber Coupler (TRAFFiC) to achieve 2D mode expansion without epitaxial regrowth or sharply-defined tips on tapered waveguides. The expanded mode size would allow 0.25 to 1 dB coupling loss to standard telecommunications fiber making smaller-core specialty fibers unnecessary, increasing misalignment tolerance, and eliminating the need for coupling optics.
Downstream Development of Viscous Fluid Wakes Behind Rod-Like Bodies (1991)

A new theory of viscous fluid wakes behind rod-like bodies is presented and is used to study the onset and downstream development of vortex street flows. Analytical solutions are obtained for the evolution of wave number, mean centerline velocity, vortex velocity, and vortex “spacing ratio” as a function of downstream distance in a laminar vortex street. A simple criterion for the onset of oscillations in the far wake, which slightly precede vortex street initiation, is also obtained. All of these solutions account for the action of viscous diffusion in spreading the street, and they are found to compare quite well with available experimental results.
방임경험이 청소년의 학교생활적응에 미치는 영향: 청소년 활동의 조절효과를 중심으로 (2015)

본 연구는 부모로부터의 방임경험이 학교생활적응에 미치는 영향에서 청소년 활동의 조절효과를 검증하고자 하였다. 이를 위해 ‘한국 아동·청소년 패널조사(KCYPS)’ 중1패널 3차년도 데이터를 활용하였으며, 전국의 청소년 2,035명을 대상으로 변인간의 관계를 분석하였다. 가설검증을 위해 Stata SE12를 이용하여 확률효과분석을 실시하였으며, 분석결과는 다음과 같다. 첫째, 방임경험은 청소년의 학교생활적응에 부적 영향을 주는 것으로 나타났다. 둘째, 청소년 활동은 방임경험과 학교생활적응과의 관계에서 유의미한 조절효과를 나타내는 것으로 확인되었다. 이러한 결과를 토대로 청소년의 학교생활적응 문제에 있어서 청소년 활동의 역할을 살피고, 구체적인 개입방안 및 실천적, 정책적 함의를 제언하였다.
Demonstration of End-to-End Automation of DNA Data Storage (2018)

Abstract We developed a complete end-to-end DNA data storage device. The device enables the encoding of data, which is then written to a DNA oligonucleotide using a custom DNA synthesizer, pooled for liquid storage, and read using a nanopore sequencer and a novel, minimal preparation protocol. We demonstrate an automated 5-byte write, store, and read cycle with the ability to expand as new technology is available.
Genomic networks of inflammatory response (INM7P.355) (2015)

Abstract Mediated by a family of Toll-like Receptors (TLRs) responses lead to transcriptional activation and synthesis of many inflammatory genes. As an example, thousands of genes are up-regulated in response to LPS (lipopolysaccharide), with many of them undergoing specific program of activation and silencing. To investigate the breadth and specificity of LPS-induced gene expression in macrophages, we compared expressional activation in response to LPS in genetically diverse mice of subspecies M.m.musculus and M.m.domesticus using next generation (NGS) RNA-sequencing. To characterize the genetic basis of LPS-response in detail, we applied a systems genetics approach, using mapping of gene expression traits with on a panel of a second-generation F2 intercross mice. Specifically, RNA from LPS-activated F2 macrophages was RNA-sequenced and hundreds of activated genes were used as phenotypic read-outs for mapping the traits. We identified several hundreds cis- and trans-acting QTL contributing to expression variation (eQTL). Many trans eQTL cluster into major groups, some of which are confined to genomic loci that do not contain known regulators of innate immune responses. We identified 227 cis-expression quantitative trait loci (cis-eQTL) that control expression. Our data provide the first genome-wide map of major regulators of the inflammatory responses in macrophages.
Robustness of full-order and restricted-structure optimal control systems (2004)

Abstract A simple method for modifying and improving the robustness of LQG optimal controllers is considered. A sensitivity costing term is introduced into the cost index and a fictitious disturbance signal, which affects robustness margins, is discussed. The influence is somewhat different on full-order and restricted-structure designs, and this is explored. Finally, the effect of a coloured measurement noise model on the robustness of the solution is investigated. Acknowledgements The author is grateful for the support of the Engineering and Physical Sciences Research Council on the Benchmarking Project Grant Number GR/R65800/01. The author is also grateful for the interest of the members of the Advanced Control Technology Club, Glasgow. Notes * To whom the correspondence should be addressed. e-mail: m.grimble@eee.strath.ac.uk Additional informationNotes on contributorsM. J. Grimble * To whom the correspondence should be addressed. e-mail: m.grimble@eee.strath.ac.uk