gebhart/patrepeval huggingface dataset:
Gait recognition: a challenging signal processing technology for biometric identification (2005)

This article provides an overview of the basic research directions in the field of gait analysis and recognition. The recent developments in gait research indicate that gait technologies still need to mature and that limited practical applications should be expected in the immediate future. At present, there is a potential for initial deployment of gait for recognition in conjunction with other biometrics. However, future advances in gait analysis and recognition - an open, challenging research area - are expected to result in wide deployment of gait technologies not only in surveillance, but in many other applications as well. This article exposes the gait analysis and recognition problem to the signal processing community and it will stimulates the involvement of more researchers in gait research in the future.
Nucleophilic Benzoylation Using a Mandelic Acid Dioxolanone as a Synthetic Equivalent of the Benzoyl Carbanion. Oxidative Decarboxylation of α-Hydroxyacids (2004)

The synthesis of alkyl aryl ketones using a mandelic acid dioxolanone as a synthetic equivalent (Umpolung) of the benzoyl carbanion is reported. The methodology involves alkylation of the mandelic acid dioxolanone, hydrolysis of the dioxolanone moiety in the alkylated products and oxidative decarboxylation of the resulting alpha-hydroxyacids. The last step is carried out in a catalytic aerobic way using a Co (III) complex in the presence of pivalaldehyde under very mild conditions.
Phase Stabilities in the Mg–Si–H System Tuned by Mechanochemistry (2014)

Reversible hydrogen storage in the Mg–Si–H system has been studied through mechanochemistry using 2Mg + Si powders as reactants under a hydrogen pressure of 9 MPa. Depending on the milling energy, the equilibrium state of this system can be tuned: either Mg2Si or 2MgH2 + Si is formed as a stable phase at high and low rotation speeds, respectively. This result is reasonably explained by the change of local temperature at the collision impact with milling speed. Therefore, we here demonstrate that reversibility in the Mg–Si–H system is feasible following the reaction Mg2Si + 2H2 ↔ 2MgH2 + Si. Indeed, the direct reaction could be fully attained by milling Mg2Si at a low rotation speed. The reverse reaction could also be triggered by milling at a high rotation speed but only when some amount of Mg2Si is used to catalyze the reaction between magnesium hydride and silicon.
High Power Mode Locked Quantum Dash 1.5 μm Laser With Asymmetrical Cladding (2012)

978-1-4673-1839-6
Ascorbate modulation of chondrocyte gene expression is independent of its role in collagen secretion. (1994)

During development and fracture repair, endochondral bone formation is preceded by an orderly process of chondrocyte hypertrophy and cartilage matrix calcification. Analysis of calcifying versus noncalcifying cartilage has identified several differences in matrix proteins; among these are appearance of a novel collagen, type X, and decreased synthesis of type II collagen, the major component of cartilage matrix. In addition, there is a marked increase in alkaline phosphatase, an enzyme expressed at high levels in all mineralizing tissues. Cultured chondrocytes can be induced to undergo these changes in gene expression and to produce calcified matrix by exposure to ascorbic acid. The mechanism by which ascorbate produces these changes has been examined by analyzing the effect of the vitamin on prehypertrophic chick embryo sternal chondrocytes. Nuclear run-on assays demonstrated that ascorbate alters mRNA levels in chondrocytes by changing the transcription rates. The fact that marked changes in mRNA levels require 1-2 days of ascorbate exposure suggested that the effect of this vitamin on gene transcription may be secondary to other, earlier ascorbate-induced effects. Since cells cultured with ascorbate produce a collagen-enriched matrix, we examined the hypothesis that transcriptional changes were secondary to altered cell-matrix interactions. Chondrocytes were cultured after attachment to tissue culture plastic, in suspension, or on plates coated with collagen type I. Comparison of alkaline phosphatase activity with and without ascorbate addition demonstrated that under all of these conditions, induction of enzyme was dependent on the presence of ascorbate. When plates containing ascorbate-conditioned chondrocyte matrix were used as substrate for naive chondrocytes, the cells continued to require ascorbate for induction of high levels of alkaline phosphatase and type X collagen mRNA. Addition of the hydroxylation inhibitor, 3,4-dehydroproline, caused marked inhibition of collagen secretion as well as accumulation of underhydroxylated collagens within the cells. However, even in the presence of this inhibitor ascorbate was effective in inducing elevated alkaline phosphatase and type X collagen. These results indicate that the ability of ascorbate to induce chondrocyte hypertrophy does not depend on production of a collagen-rich matrix.
Front Cover: Molecular Metallocorrole–Nanorod Photocatalytic System for Sustainable Hydrogen Production (ChemSusChem 17/2022) (2022)

The Front Cover shows the solar-driven photocatalytic generation of hydrogen from water. It is accomplished via a successful combination of nanorod photocatalysts that have proven record activity for the water reduction half-reaction, with molecular metallocorroles suitable for catalyzing the accompanying oxidation reactions. The utilization of redox species as charge transfer shuttle between freely mixed molecular catalysts and rods afford a simple and elegant alternative to a chemical linkage, which results in high quantum efficiency for hydrogen production. In place of a sacrificial scavenger capable of extracting but a single hole, the molecular metallocorrole catalyst is found to successfully handle nearly 300,000 holes during its lifespan. More information can be found in the Research Article by K. Dong, T.-A. Le et al.
Using genetic microbial source tracking (MST) markers to identify fecal pollution sources in spring water of a large alpine karst catchment (2019)

Highlights Apply MST markers as E. coli does not provide information on fecal pollution sources Support water resource management (SDG 6.5) by genetic MST marker detection Identified animals instead of suspected human sewage disposal as emission sources Demonstrate how to generate robust MST information at head water catchments Tiered MST approach as interface between E. coli diagnostics and QMRA Graphical abstract Management objective Fecal pollution analysis still relies on cultivation-based E. coli and intestinal Enterococci (FIB) standard methods. However, these approaches do not give information on the kind of pollution sources. This study demonstrates how to identify pollution sources based on the application of genetic microbial source tracking (MST) markers at alpine spring water to guide target-oriented catchment protection and management. Location and description of the system The study site is located in the Northern Calcareous Alps (Austria) and drains a large Triassic limestone aquifer between 820 and 1828 m (catchment approx. 70 km2). Vegetation comprises summer pastures, natural calcareous alpine swards with open krummholz and forests. Potential fecal pollution sources include humans, livestock (cattle) and wild life. During base-flow conditions the observed spring has excellent water quality. In contrast, heavy rain events can result in high FIB concentrations. Description of the method The integrated multi-tiered approach covers, i) pollution source profiling using information from catchment survey activities, ii) hypothesis formulation on the potentially important fecal pollution sources and MST assay selection, and finally iii) hypothesis testing at the spring using hydrology-driven sampling and data stratification with concurrent analysis of FIB and genetic MST markers. Outcome and recommendations FIB could be traced back to animal fecal pollution sources (ruminants). Despite of being initially suspected, human sewage was not identified as the source of contamination. Results verified catchment protection measures and also guided further hazard and risk assessment activities. The tiered approach proved very valuable for MST. It is also suitable for the application in other complex headwater catchments, since the used parameters and methods can be adapted to the specific situation. Read more? Scroll down to the detailed description of this case study
Discrete-event Simulation of a Wide-area Health Care Network (1995)

The simulation models provided an estimate of network performance and telecommunication cost in a specific Canadian province. At the expected operating point, network performance appeared to be relatively insensitive to increases in data volume. Similar results might be anticipated in other rural states and provinces in North America where a telephone-based network is desired.
Expression of the c-kit receptor in human lymphomas is restricted to Hodgkin's disease and CD30+ anaplastic large cell lymphomas (1994)

The product of the proto-oncogene c-kit is a transmembrane receptor protein that plays an important role in the regulation of normal and neoplastic hematopoiesis via the interaction with its specific ligand termed stem cell factor. To examine whether c-kit product is possibly involved in the pathogenesis of human lymphomas, we analyzed the expression of the c-kit protein in neoplastic cells from a variety of lymphoid tumors by immunostaining of lymph node frozen sections with the 17F11 antibody, detecting an extracellular epitope of the c-kit receptor, and of c-kit RNA by Northern blot hybridization. Of 24 nonHodgkin's lymphomas (NHL) of B- and T-cell phenotype, none expressed immunodetectable c-kit protein that was also not evidenced in lymphoid cells of reactive lymph nodes and normal tonsils. In contrast, c-kit protein was expressed by Reed-Sternberg cells and their mononuclear variants from 11 of 21 Hodgkin's disease (HD) cases, and in tumor cells from 11 of 16 cases of CD30+ anaplastic large cell lymphoma (ALCL). c-kit specific mRNA was also detected in lymph node tissues from HD and ALCL cases but not in neoplastic tissues from NHL other than ALCL. In addition, c-kit/CD30+ tumor cells were evidenced by flow cytometry in a patient displaying massive bone marrow involvement by ALCL. With the exclusion of lymphocyte predominance cases of HD that resulted c-kit expression and the other histologic subtypes of HD or the immunologic phenotype of tumor cells (B, T, nonB-nonT) in both HD and ALCL. The highly restricted expression of the c-kit product among human lymphomas to HD and ALCL provides a further biologic link between these two closely related lymphoma entities.
Abstract 2972: Functional Characterization of Human Induced Pluripotent Stem Cell Derived Cardiomyocytes (2009)

[Background] Although many genetic cardiac disorders have been identified, their underlying genetic mechanisms are largely unknown. In this regard, human induced pluripotent stem (iPS) cells may pr...
Development of a total landed cost and risk analysis model for global strategic sourcing (2008)

Thesis (M.B.A.)--Massachusetts Institute of Technology, Sloan School of Management; and, (S.M.)--Massachusetts Institute of Technology, Engineering Systems Division; in conjunction with the Leaders for Manufacturing Program at MIT, 2008.
Antiferromagnetism in the vortex cores ofYBa2Cu3O7−δ (2003)

We report spatially resolved nuclear-magnetic-resonance measurements on a high-temperature superconductor that indicate the presence of correlated antiferromagnetic fluctuations in the vortex core. The nuclear-spin-lattice relaxation rate ${1/}^{17}{T}_{1}$ of planar ${}^{17}\mathrm{O},$ in near-optimally doped ${\mathrm{YB}}_{2}{\mathrm{Cu}}_{3}{\mathrm{O}}_{7\ensuremath{-}\ensuremath{\delta}},$ was measured. Outside of the core, ${(}^{17}{T}_{1}{T)}^{\ensuremath{-}1}$ is independent of temperature consistent with theoretical predictions for a d-wave superconductor. In the vortex core, ${(}^{17}{T}_{1}{T)}^{\ensuremath{-}1}$ increases with decreasing temperature following an antiferromagnetic Curie-Weiss law.
Treatment of Severe Spondylolisthesis in Children by Reduction and L4-S4 Posterior Segmental Hyperextension Fixation (1992)

Twenty children with severe lumbosacral spondylolisthesis underwent reduction, posterolateral fusion, and posterior fixation with an L4 to S2, 3, and 4 sublaminar wired rectangular rod to lessen lumbosacral kyphosis, allow early ambulation, and maintain correction. All patients had a postural deformity, 10 had preoperative neurologic findings, and 8 had severe pain. The average percentage of slip improved from 76% preoperatively to 55% postoperatively, and the slip angle improved from 25 degrees to 5 degrees (p < 0.0001). All patients had solid fusion by 6 months and no progression at 43 month follow-up on the average. We conclude that this technique reliably provides partial reduction, solid fixation, and fusion for patients with severe spondylolisthesis while allowing early ambulation. As with any spondylolisthesis reduction technique, neurologic risk should limit this procedure to well-selected patients.
Profiling and Understanding Virtualization Overhead in Cloud (2015)

Virtualization is a key technology for cloud data centers to implement infrastructure as a service (IaaS) and to provide flexible and cost-effective resource sharing. It introduces an additional layer of abstraction that produces resource utilization overhead. Disregarding this overhead may cause serious reduction of the monitoring accuracy of the cloud providers and may cause degradation of the VM performance. However, there is no previous work that comprehensively investigates the virtualization overhead. In this paper, we comprehensively measure and study the relationship between the resource utilizations of virtual machines (VMs) and the resource utilizations of the device driver domain, hypervisor and the physical machine (PM) with diverse workloads and scenarios in the Xen virtualization environment. We examine data from the real-world virtualized deployment to characterize VM workloads and assess their impact on the resource utilizations in the system. We show that the impact of virtualization overhead depends on the workloads, and that virtualization overhead is an important factor to consider in cloud resource provisioning. Based on the measurements, we build a regression model to estimate the resource utilization overhead of the PM resulting from providing virtualized resource to the VMs and from managing multiple VMs. Finally, our trace-driven real-world experimental results show the high accuracy of our model in predicting PM resource consumptions in the cloud datacenter, and the importance of considering the virtualization overhead in cloud resource provisioning.
Early Burn-In Parasitic Conduction in 500 °C Durable SiC JFET ICs (2023)

All prior reports of long-term 500 °C operation of SiC JFET-R ICs have noted the existence of an initial “burn-in” period of changes in measured electrical characteristics for the first few hundred hours oven-testing. This work reports measurements of “burn-in parasitic MOSFET conduction” that can substantially impact the performance of some circuits during initial heat-up of JFET ICs, but then subsequently disappears after a few hours of operation at 500 °C. The behavior appears generally consistent with the known MOS phenomenon of bias-temperature driven redistribution of mobile ionic contamination. Approaches for further mitigating this initial burn-in conduction mechanism are discussed.
The Pseudo-Pelger HuËt Cell—A New Permanent Radiation Biomarker (2017)

Using archival peripheral blood slides obtained from patients in the 1958 Y-12 criticality accident, the authors have recently described the pseudo-Pelger Huët anomaly (PHA) in neutrophils as a new radiation-induced biomarker. The current work provides additional evidence that PHA is also a permanent biomarker, potentially useful in retrospective dosimetry. In the Y-12 cohort, the high dose group (n = 5, 2.98-4.61 Gy-Eq) exhibited 13.0 ± 0.85 % Pelger Huët cells (mean ± SEM) in the neutrophil population compared to 6.8 ± 1.6 % in the low dose group (n = 3, 0.29-0.86 Gy-Eq; p = 0.008). An age and gender-matched control group (n = 8) exhibited 3.6 ± 0.9 % PH cells. Results of a one-way ANOVA show that the high dose group is statistically different from both the low dose group and the control group (p = 0.002). In the Y-12 cohort, PHA appears <12 h post-accident and is permanent for more than 16 y. Similar long-term persistence of the PHA mutation has been obtained from examination of peripheral blood slides from the 1971 Co accident at the Variable Dose Rate Irradiation Facility (VDRIF) in Oak Ridge, TN. In order to investigate the pseudo-PH cell as a biomarker in animal studies under well controlled dosimetry, peripheral blood slides were obtained from animals in a nonhuman primate (NHP) (Macaca mulatta) total-body irradiation (TBI) model (Co γ rays at 0.6 Gy min; dose range 1-8.5 Gy, LD50/60 6.44 Gy). In the NHP studies, the first measurement of PHA is taken at 5 h post-irradiation, then daily for days 1-5 and every 5-10 d thereafter. In the TBI model, the PH cell appears quickly (<5 h) post-irradiation, and the dose-dependent PH percentage is constant from 1 d over the 60-d monitoring period of the experiments. Using the average of data from 1-60 d, a linear dose response (PHA % slope = 0.49 ± 0.07 % Gy, r = 0.92) is obtained over the dose range 0-8.5 Gy. The authors conclude that ionizing radiation induces dose-dependent internuclear bridges in circulating neutrophils, and this morphological change can be used both as an acute phase biomarker and as a tool for retrospective dosimetry.
人的哲学是一门精密的科学——列维-斯特劳斯的结构人类学观点评介 (1983)

一、人类学与人不论人们是否同意列维-斯特劳斯的观点,他在“结构人类学”方面的优异成就足以保证他的思想在未来的思想史中占一席位置。列维-斯特劳斯以人的意义为标准,把人类学看作是一门包括所有科学知识的综合性学科。人文主义的科学把宇宙说成是主观的,把人贬低为意识或“精神”的产物;自然科学则认为宇宙是客观的,把人归结为带电物质的微粒;而社会科学,诸如历史学、心理学、经济学和社会学,都企图在这些对立的
Cicatricial Alopecia Research Foundation meeting, May 2016: Progress towards the diagnosis, treatment and cure of primary cicatricial alopecias (2018)

Primary cicatricial alopecias (PCAs) are a group of skin diseases in which there is progressive and permanent destruction of hair follicles followed by replacement with fibrous tissue. Unfortunately, by the time patients seek clinical evaluation of their hair loss, the skin is already inflamed and/or scarred, so there is little hope for a return to their normal hair growth pattern. Clinical and basic science investigations are now focusing on three forms of human PCA: lichen planopilaris (LPP), frontal fibrosing alopecia (FFA) and central centrifugal cicatricial alopecia (CCCA). Transcriptome, lipidome and other new technologies are providing new insight into the pathogenesis of some of these diseases that are being validated and further investigated using spontaneous and genetically engineered mouse models.
Rational Design and Tuning of Ribozyme-Based Devices (2012)

A synthetic gene-regulatory device platform was described by modularly assembling three RNA components encoding distinct functions of sensing, transmission, and actuation. The molecular binding at the sensor component is translated by the transmitter component through a strand-displacement event to modulate activity of the actuator component, which then interacts with cellular transcriptional machinery to affect gene expression levels. Here, we provide some general guidelines on linking RNA components to construct gene-regulatory devices and strategies to tune device regulatory activities through an RNA folding -program for specific cellular applications.
Triterpenoid total synthesis. Part 6. Synthesis of testudinariols A and B, triterpene metabolites of the marine mollusc Pleurobrancus testudinarius. (2001)

Testudinariols A (1) and B (1′) are ichthyotoxic and structurally unusual triterpene alcohols isolated from the skin and the mucus of the marine mollusc Pleurobrancus testudinarius. The first synthesis of (+)-1 and (+)-1′ was achieved by starting from (R)-glycidol.
Review of the Relationship of Restless Legs Syndrome and Periodic Limb Movements in Sleep to Hypertension, Heart Disease, and Stroke (2009)

Evidence is reviewed documenting an intimate relationship among restless legs syndrome (RLS) / periodic limb movements in sleep (PLMS) and hypertension and cardiovascular and cerebrovascular disease. Sympathetic overactivity is associated with RLS/PLMS, as manifested by increased pulse rate and blood pressure coincident with PLMS. Causality is far from definitive. Mechanisms are explored as to how RLS/PLMS may lead to high blood pressure, heart disease, and stroke: (a) the sympathetic hyperactivity associated with RLS/PLMS may lead to daytime hypertension that in turn leads to heart disease and stroke; (b) in the absence of daytime hypertension, this sympathetic hyperactivity may predispose to heart disease and stroke either directly or indirectly via atherosclerotic plaque formation and rupture; and (c) comorbidities associated with RLS/PLMS, such as renal failure, diabetes, iron deficiency, and insomnia, may predispose to heart disease and stroke. One theoretical cause for sympathetic hyperactivity is insufficient All diencephalospinal dopaminergic neuron inhibition of sympathetic preganglionic neurons residing in the intermediolateral cell columns of the spinal cord. We cannot exclude the possibility that peripheral vascular, cardiovascular, and cerebrovascular disease may also contribute to RLS/PLMS, and mechanisms for these possibilities are also discussed.
Modeling and design of service-oriented architecture (2005)

Component-based development (CBD) and Web services (WS) are today widely used for building flexible enterprise-scale systems organized in a service-oriented architecture (SOA). In order to gain the full benefits of the emerging technology and standards, an effective approach for modeling and designing this complex distributed computing model is required. Current efforts in this direction are much behind the technology ones. This work presents an approach to SOA modeling and design based on the concept of service component and standard UML modeling constructs. The interface of a service component goes well beyond the list of operation signatures to specify the complete contract between the service provider and consumer. The paper defines service components of different types, scope and granularity and puts them in the context of a model-driven design approach to provide bidirectional traceability between business requirements and software artifacts.
Histamine H2 receptor stimulation increases gastric emptying in monkeys (1988)

We studied the effect of the specific H2 receptor agonist dimaprit on gastric emptying using a dye dilution technique in five chair-adapted rhesus monkeys to determine simultaneously gastric emptying and H+ secretion. Continuous subcutaneous injections of either saline alone or dimaprit (15, 30, 60, 120, and 240 nmol.kg-1.min-1) were given in random order on separate days. Both fractional emptying rate and H+ output were significantly increased by higher doses of dimaprit, with resulting twofold concurrent increase of intragastric H+ concentration. Because intragastric administration of H+ decreases gastric emptying and secretion, we evaluated the possibility that the stimulatory action of a histamine H2 agonist was underestimated when gastric pH was greater during control than after dimaprit. When exogenous HCl was added to the stomach to achieve H+ concentrations similar to those measured after dimaprit, both fractional emptying and H+ secretion were decreased twofold. When these "acidified control values" were used as a point of comparison, the stimulatory effect of dimaprit on both fractional emptying and gastric secretion was greater, suggesting that the stimulatory actions of dimaprit are underestimated if one does not take into account the differences in intragastric H+ concentrations.