gebhart/patrepeval huggingface dataset:
Effect of Raw Multi-Wall Carbon Nanotubes on Morphology and Separation Properties of Polyimide Membranes (2010)

Raw multi wall carbon nanotubes (r-MWCNTs) were embedded as fillers inside the polyimide (PI) matrix and PI/r-MWCNTs mixed matrix membranes were fabricated by the phase inversion method. The TEM images and permeation results using helium as test gas showed that r-MWCNTs were generally closed ended and acted as impermeable nano particles. Gas permeation tests using CO2 and CH4 showed that the addition of r-MWCNTs into the dope solution increased the CO2/CH4 separation factor while decreasing the carbon dioxide and methane permeances. When the r-MWCNTs content was increased from 0% to 6 wt.%, permeance of CO2 in the flat sheet mixed matrix membranes decreased from 9.15 GPU to 5.49 GPU and CO2/CH4 separation factor increased from 19.05 to 45.75. Identical to flat sheet mixed matrix membranes, the addition of 2 wt.% r-MWCNTs into a spinning dope increased the CO2/CH4 separation factor from 46.61 to 72.20. The glass transition temperature of the mixed matrix flat sheet membranes increased with an increase in the r-MWCNTs content. This implies a good segmental-level attachment between the two phases that forms a rigidified polymer region at the polymer/r–MWCNTs interface. FESEM images showed well dispersed r-MWCNTs in the polymer matrix at a loading of 2 wt% r-MWCNTs.
Graphene Quantum Dots for Fluorescent Labeling of Gelatin‐Based Shear‐Thinning Hydrogels (2021)

Injectable Biomaterials In article number 2000113, Ali Khademhosseini, Samad Ahadian, and co-workers use biocompatible graphene quantum dots for imaging a physically crosslinked and injectable shear-thinning biomaterial of gelatin hydrogel and silicate nanoplatelets. The biomaterial shows a robust and stable fluorescence signal in vitro and in animal models, suggesting a great potential in long-term tracking and non-invasive monitoring of the biomaterial in therapeutic applications.
Renal Ischemia/Reperfusion Injury in Soluble Epoxide Hydrolase-Deficient Mice (2016)

These results indicate that the potential beneficial effects of reducing EET degradation were obliterated by a thus far unknown mechanism leading to kidney-specific up-regulation of 20-HETE formation in sEH-KO-mice.
Co-clustering of diseases, genes, and drugs for identification of their related gene modules (2016)

Finding gene clusters that can be shared between drugs and diseases plays an important role in drug discovery. Targeting disease causing genes directly in drug development can increase the chance of drug approval through the clinical phase. This paper introduces a new co-clustering approach on the tripartite graph of genes, drugs, and diseases. As a result of co-clustering, gene modules and their related drugs and diseases are identified. It is shown that identified gene modules are functionally related. In addition the resulted gene modules are closely connected to each other in the protein-protein interaction network compared to that of random gene selection. The resulting gene modules can be used for investigating the genes that can be targeted with new drugs for treatment of diseases that are co-clustered with them. The proposed method is scalable and can be used for other multi-view graph co-clustering applications like social networks.
Occluding contour detection using affine invariants and purposive viewpoint control (1994)

We present an approach for identifying the occluding contour and determining its sidedness using an active (i.e., moving) observer. It is based on the non-stationarity property of the visible rim: When the observer's viewpoint is changed, the visible rim is a collection of curves that "slide," rigidly or non-rigidly over the surface. We show that the absenter can deterministically choose three views on the tangent plane of selected surface points to distinguish such curves from stationary surface curves (i.e., surface markings). Our approach demonstrates that the occluding contour can be identified directly, i.e., without first computing surface shape (distance and curvature).< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Retrospective Pooled Screening for SARS-CoV-2 RNA in late 2019 (2020)

Abstract Reports have emerged documenting earlier SARS-CoV-2 cases than previously recognized. To investigate this possibility in the Bay Area, we retrospectively tested 1,700 samples from symptomatic individuals for the last 2 months of 2019. No SARS-CoV-2 positive pools were identified, consistent with limited transmission in this population at this time.
Adaptive vector quantization of picture signals in discrete cosine transform domain (1987)

Abstract This paper proposes the adaptive discrete cosine transform coding with vector quantization (adaptive DCT‐VQ), as a highly efficient coding for the picture signal. In the proposed method, the vector quantization is performed by applying the discrete cosine transform to the picture subblock and partitioning the transformed domain into several vectors. By regarding the transformed domain as more than one vector, the complexity in the coding is reduced. Each vector quantizer is designed according to the standard probability distribution of the cosine transform coefficient, and the universality of the vector quantizer is realized. The mode‐selecting type adaptive control is introduced, to effect the adaptive control of the coding parameters according to the local property of the picture. To cope with the large bit allocation resulting from the adaptive control, each vector quantizer has two‐stage structure thereby reducing the coding complexity. As a result of the performance evaluation by simulation, it was verified that the proposed coding method has a higher performance than the conventional adaptive cosine transform coding and has much less complexity than the vector quantization in the original space domain.
ACP-Based Control and Management of Urban Rail Transportation Systems (2011)

Urban rail transportation (URT) has long become the preferred public transportation choice for major metropolitan areas such as New York, London, Paris, Moscow, Tokyo, and Beijing. The highest daily record for Beijing's URT reached 5.71 million passenger trips in 2010, which makes the network extremely crowded in rush hours. To accommodate the increasing demand for URT, the service frequencies have been increased tremendously. To address these safety, efficiency, and reliability issues, the paper presents a novel parallel system for URT operations that uses the concept of parallel system and computational experiments based on artificial systems (ACP). The parallel URT system can analyze and facilitate passenger-flow management, vehicle scheduling, and other operational issues while considering human-related, environmental, and other social and economical factors.
Utility and Efficiency of Homologous Recombination for Introducing Targeted Modifications to the Pig Genome (2012)

The production and utilization of genetically modified animals greatly improves their utility in agriculture, as biomedical research models of human disease, for the production of recombinant pharmaceutical proteins, and for production of organs with greater potential for xenotransplantation. While numerous strategies have been utilized in the production of transgenic large animals, cell-based transgenesis followed by somatic cell nuclear transfer (SCNT) is currently the most widely applied method. We constructed a targeting vector with 2774 and 1890 bp arms of homology flanking a neomycin resistant gene. Following delivery of the DNA targeting vector into the porcine fetal fibroblasts by electroporation and selection with G418, PCR and sequencing confirmed one of 547 transgenic clonal colonies contained the targeted introduction of the neomycin resistance gene. Genetically modified fibroblast donor cells can be utilized for SCNT for the development of genetically modified pigs to study biological mechanisms important for animal agriculture and to create biomedical models.
Improved Hot-Electron Reliability in Strained-Si nMOS (2004)

Strained-Si/relaxed-Si/sub 1-x/Ge/sub x/ structures provide a viable means of improving CMOS performance. For nMOS devices, the tensile strain in pseudomorphic Si on relaxed-Si/sub 1-x/Ge/sub x/ splits the six-fold degeneracy of the conduction band minimum, rendering increased electron mobility due to a lower in-plane effective mass and reduced intervalley scattering. In this paper, in addition to confirming enhanced performance for biaxial-strained-Si nMOS, we present hot-electron degradation characteristics for the first time, showing improvement over bulk Si.
Electrical and optical properties of W-doped ZnO films grownon (11\bar{2}0) sapphire substrates using pulsed laser deposition (2014)

WxZn1−xO films with various doping concentration were prepared using pulsed laser deposition (PLD) on the (1120) face of sapphire. The c-axis-oriented WxZn1−xO films were grown without in-plane rotation domains when the W content in the films was below 3.6 at.%. The films exhibit a high transmittance of approximately 80% in the visible-near infrared region regardless of the W content, and no shift of the absorption edge was observed. From the results of Hall measurements, it was revealed that the doping efficiency of W in the films was <0.15 electrons/W. The electron mobility of the WxZn1−xO films was 14–35 cm2 V−1 s−1, which is relatively low compared with that of the undoped ZnO film grown using PLD. The low doping efficiency and electron mobility are considered to be attributed to the formation of defects resulting from the W-doping.
The use of anti-lymphocyte globulin in Rh-conflict pregnancy (1980)

A clinical study of anti-lymphocyte globulin as a means of suppressing Rh isosensitization in 56 pregnant women was carried out. Its use in combination with other methods contributed to a more favorable course of pregnancy, complicated by Rh-conflict. Anti-lymphocyte globulin causes a decrease in the pathogenic activity of the mother's immunological system in relation to the fetus.
A low-power SiGe D-band total power radiometer with NEPmin of 1.4 fW/Hz½ and NETD of 0.25K (2016)

This paper presents a low-noise SiGe radiometer at 136 GHz developed in an IBM 90 nm SiGe BiCMOS technology. The radiometer chip consumes 45 mW and results in a minimum NEP of 1.4 fW/Hz <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">½</sup> with a peak responsivity of 52 MV/W at 136 GHz and a noise equivalent temperature difference (NETD) of 0.25K (τ = 3.125 mS). To the best of our knowledge, this is the lowest temperature resolution in silicon technologies at D-band.
Direct modulation of 13 μm quantum dot lasers on silicon at 60 °C (2016)

We demonstrate direct modulation of an InAs/GaAs quantum dot (QD) laser on Si. A Fabry-Pérot QD laser was integrated on Si by an ultraviolet-activated direct bonding method, and a cavity was formed using cleaved facets without HR/AR coatings. The bonded laser was operated under continuous-wave pumping at room temperature with a threshold current of 41 mA and a maximum output power of 30 mW (single facet). Even with such a simple device structure and fabrication process, our bonded laser is directly modulated using a 10 Gbps non-return-to-zero signal with an extinction ratio of 1.9 dB at room temperature. Furthermore, 6 Gbps modulation with an extinction ratio of 4.5 dB is achieved at temperatures up to 60 °C without any current or voltage adjustment. These results of device performances indicate an encouraging demonstration on III-V QD lasers on Si for the applications of the photonic integrated circuits.
A Feedback Regulatory Module Formed by LITTLE ZIPPER and HD-ZIPIII Genes (2007)

The Arabidopsis thaliana REVOLUTA (REV) protein is a member of the class III homeodomain-leucine zipper (HD-ZIPIII) proteins. REV is a potent regulator of leaf polarity and vascular development. Here, we report the identification of a gene family that encodes small leucine zipper-containing proteins (LITTLE ZIPPER [ZPR] proteins) where the leucine zipper is similar to that found in REV, PHABULOSA, and PHAVOLUTA proteins. The transcript levels of the ZPR genes increase in response to activation of a steroid-inducible REV protein. We show that the ZPR proteins interact with REV in vitro and that ZPR3 prevents DNA binding by REV in vitro. Overexpression of ZPR proteins in Arabidopsis results in phenotypes similar to those seen when HD-ZIPIII function is reduced. We propose a negative feedback model in which REV promotes transcription of the ZPR genes. The ZPR proteins in turn form heterodimers with the REV protein, preventing it from binding DNA. The HD-ZIPIII/ZPR regulatory module would serve not only to dampen the effect of fluctuations in HD-ZIPIII protein levels but more importantly would provide a potential point of regulation (control over the ratio of inactive heterodimers to active homodimers) that could be influenced by other components of the pathway governing leaf polarity.
Recent Advances in Black Phosphorus‐Based Electronic Devices (2018)

Abstract The rediscovery of graphene in the recent past has propelled the rapid development of exfoliation and other thin layer processing techniques, leading to a renewed interest in black phosphorus (BP). Since 2014, BP has been extensively studied due to its superior electronic, photonic, and mechanical properties. In addition, the unique intrinsic anisotropic characteristics resulting from its puckered structure can be utilized for designing new functional devices. In retrospect, significant efforts have been directed toward the synthesis, basic understanding, and applications of BP in the fields of nanoelectronics, ultrafast optics, nanophotonics, and optoelectronics. Here, the recent development of BP‐based devices, such as nanoribbon field‐effect transistors, complementary logic circuits, memory devices, and the progress made in meeting the challenges associated with contact resistance, in‐plane anisotropy, and advanced gate stack, are reviewed. Finally, the prospects of 2D materials in meeting the International Technology Roadmap for Semiconductor requirements for the year 2030 are discussed.
SNR analysis of 3D magnetic resonance tomosynthesis (MRT) imaging (2012)

In conventional 3D Fourier transform (3DFT) MR imaging, signal-to-noise ratio (SNR) is governed by the well-known relationship of being proportional to the voxel size and square root of the imaging time. Here, we introduce an alternative 3D imaging approach, termed MRT (Magnetic Resonance Tomosynthesis), which can generate a set of tomographic MR images similar to multiple 2D projection images in x-ray. A multiple-oblique-view (MOV) pulse sequence is designed to acquire the tomography-like images used in tomosynthesis process and an iterative back-projection (IBP) reconstruction method is used to reconstruct 3D images. SNR analysis is performed and shows that resolution and SNR tradeoff is not governed as with typical 3DFT MR imaging case. The proposed method provides a higher SNR than the conventional 3D imaging method with a partial loss of slice-direction resolution. It is expected that this method can be useful for extremely low SNR cases.
Application of rep-PCR technique for the identification of lactic acid bacteria. (2010)

In this paper isolates from traditionally fermented dairy were characterized in the Tongliao range of Inner Mongolia by rep-PCR technique.Diversity of Lactic acid bacteria is investigated.Differentiation ability of single primer PCR-BOX-PCR was strong to the tested strains.From the results we found that lactic acid bacteria shown high diversity in this region.Lactobacillus plantarum,Lactobacillus helveticus,Lactobacillus casei,Enterococcus faecalis,Lactococcus lactis and Leuconostoc pseudomesenteroides were the normal species.Among these species Lactobacillus plantarum is the dominant species.In addition we found that the representative bands of the same group of Lactic acid bacteria species shared similar characterization;furthermore this provides theoretical basis for the rapid identification of lactic acid bacteria.
Ring finger protein 43 associates with gastric cancer progression and attenuates the stemness of gastric cancer stem-like cells via the Wnt-β/catenin signaling pathway (2017)

Our findings indicated that RNF43 might not only participate in gastric cancer progression, but also attenuate the stemness of gastric cancer stem-like cells through the Wnt/β-catenin pathway.
Three‐dimensional quantification of circulation using finite‐element methods in four‐dimensional flow MR data of the thoracic aorta (2021)

We propose a novel 3D formulation to estimate the circulation in the thoracic aorta, which can be used to assess the differences between normal and diseased hemodynamic from 4D-Flow MRI data. This method also can correctly differentiate between the visually seen right- and left-handed helical flow, which suggests that this approach may have high clinical sensitivity, but requires confirmation in longitudinal studies with a large cohort.
[Hepatic resection in the fetal rabbit. Histologic comparison of tissue regeneration in the fetus versus the adult]. (1996)

Fetal tissues present peculiar features of repair after injury. Although the development of fetal hepatocytes have already been studied in vitro and in transplant models, an in vivo study of fetal liver regeneration is still missed in the literature, to the best of our knowledge. Eight time-dated pregnant California rabbits (23, 24, 25, 30 days of gestational age) and 2 adult male California rabbits were anesthetized following a standardized i.v. protocol (ketamine 50 mg/kg; xilazine 5 mg/kg; propiopromazine 0.75 mg/kg; spontaneous breathing; no anesthetic gas). All the pregnant does underwent a midline laparotomy and a minimal hysterotomy to approach a fetus per each animal. In 2 cases, 1 fetus was delivered and prior to sacrifice the fetal liver was sampled in toto (30 days of gestational age). These pregnancies were allowed to continue to term and were uneventful with a full-term spontaneous delivery of the remaining fetuses. In the other 6 pregnancies, after the hysterotomy, the fetal abdomen was entered through a right-sided longitudinal incision and the liver was partially resected by thermocauterization. Fetal abdomen was closed in 1 layer (non absorbable suture 7-0). The fetus was then returned in the uterus and, after amniotic fluid restoration with warmed saline, the hysterotomy was sutured in double layer (polyglycolic 5-0). Maternal abdomen was closed in 1 layer (polyglycolic 4-0) and the skin in a continuous overlying fashion (silk 3-0). The abdominal cavity of the 2 adult male rabbits was entered through a right subcostal incision. Partial liver resection was performed, and abdominal and skin closure followed the same techniques used for the pregnant does. The treated livers were then sampled in toto at 24, 48, 72 hrs and 4 days after surgery from the fetuses, and at 7 days from the adult rabbits. Histological stains were: H & E; Van Gieson; Masson; Alcian Bleu; PAS. Fetal histology showed a low inflammatory reaction poor in PMN cells with minimal deposition of collagen and a high amount of glycogen in the hepatocytes. The inflammatory response to resection was much more evident in the adult samples as much as the abundant intra and extra-cellular deposition of collagen associated to a minor amount of intracellular glycogen. The peculiar features of liver regeneration in the fetus, deserve further experimental studies.
Issues and Requirements for SNI Encryption in TLS (2019)

This draft describes the general problem of encrypting the Server Name
Identification (SNI) TLS parameter. The proposed solutions hide a
Hidden Service behind a fronting service, only disclosing the SNI of
the fronting service to external observers. The draft lists known
attacks against SNI encryption, discusses the current co-tenancy
fronting solution, and presents requirements for future TLS layer
solutions. In practice, it may well be that no solution can meet
every requirement, and that practical solutions will have to make some
compromises.
Platelet count at baseline (Plt) and outcomes in patients (pts) with advanced hepatocellular carcinoma (HCC) treated with sorafenib (S) in CALGB80802 (Alliance) (C8). (2018)

e16107 Background: CALGB 80802 study determined that doxorubicin plus sorafenib did not improve survival (OS) compared to sorafenib. The association between platelet count and outcome of patients with HCC is inconsistent and controversial. A retrospective exploratory analysis evaluated the demographics, OS, time to progression (TTP), and progression free survival (PFS) by platelet count in HCC pts treated with sorafenib. Considering the negative outcome of CALGB 80802, the focus herein is on the standard of care sorafenib arm. Methods: The prognostic value of baseline platelet count was evaluated by Cox regression models, adjusting for clinical and pathological factors. Based on an average normal platelet cutoff level, patients were stratified on platelet count <150 and ≥150 × 109/L. Adjusted hazard ratios (HRadj) and 95% confidence intervals (CI) were reported. Results: 61 patients had platelet count <150 × 109/L and 109 had platelet count ≥150 × 109/L. Low platelet count <150 × 109/L was associated with male gender; low T stage, WBC count, ANC, and granulocyte count; high hemoglobin and bilirubin. High platelet count ≥150 × 109/L had shorter PFS and OS that did not reach statistical significance, and was significantly associated with shorter TTP (P=0.04), (Table). Conclusions: For sorafenib, TTP was significantly shorter among pts with platelet count ≥ 150 × 109/L. Platelet count < 150 × 109/L is suggestive of improved OS and PFS compared to pts with platelet count ≥ 150 × 109/L. Platelet count may be a prognostic factor of for patients with advanced HCC and warrants further study. Support: U10CA180821, U10CA180882; U10CA077202, U10CA180820, U10CA180888; Clinical trial information: NCT01015833.Platelet× 109/L Events (number) Median (months) HRadj (95% CI) P OS ≥ 150 93 7.6 1.26 (0.86-1.84) 0.25 < 150 51 13.4 Ref TTP ≥ 150 79 3.6 1.56 ( 2.00-2.41) 0.04 < 150 39 5.8 Ref PFS ≥ 150 100 3.4 1.39 (0.95-2.04) 0.08 < 150 54 5.0 Ref
Isolation and characterization of phytotoxins associated with Streptomyces scabies (1989)

Two phytotoxins capable of inducing scab-like lesions on immature potato tubers were isolated from field grown and aseptically cultured potato tubers that had been infected by Streptomyces scabies; the compounds were characterized by spectral methods and partial syntheses as unique 2,5-dioxopiperazines.
ChemInform Abstract: REACTION OF 2‐BENZOYLCYCLOHEXANONE AND THE CORRESPONDING ENAMINE WITH MALONONITRILE (1983)

Abstract Die Titelverbindung (I) und das Enamin (III) reagieren mit Malodinitril zur gleichen Verbindung, dem Tetrahydronaphthalin (II).