gebhart/patrepeval huggingface dataset:
Relationship between cardiovascular symptoms, health status assessment and cardiomyopathy in the obstetric population (2022)

Abstract Background Pregnancy related cardiomyopathy is a significant cause of maternal morbidity and mortality globally. A presumed overlap between normal pregnancy-associated symptoms and clinical symptoms of cardiomyopathy contributes to delays in diagnosis and increased risk of maternal mortality. Purpose We sought to evaluate the association between patient-reported cardiovascular symptoms and the presence of cardiomyopathy among pregnant and postpartum patients. We hypothesize that individual cardiovascular symptoms are unrelated to the presence of cardiomyopathy. We also evaluated the use of a novel adaptation of a validated health status questionnaire in relation to cardiomyopathy. Methods We enrolled 48 pregnant (&amp;gt;13 weeks) and postpartum (up to 12 months) participants in a prospective study between October 2021 and February 2022. All study participants completed a baseline questionnaire, which included current cardiovascular symptoms, an assessment of health status using an adapted version of the Kansas City Cardiomyopathy Questionnaire (KCCQ-12), followed by a resting transthoracic echocardiogram on the same day. We defined cardiomyopathy as a left ventricular ejection fraction (LVEF) &amp;lt;50% based on 2-D echocardiography. Fisher's exact and Wilcoxon rank-sum tests were employed to evaluate the association between reported cardiovascular symptoms, the adapted KCCQ-12 (KCC-A) score, and cardiomyopathy. Results At the time of enrollment, 67% were pregnant and 33% postpartum. Forty-eight percent identified as White, 31% as Black, 10% as Asian, and 10% as other race. The median age was 31 years (Q1: 28, Q3: 35) and 6% had an LVEF &amp;lt;50%. We found no statistically significant association between four reported cardiovascular symptoms (shortness of breath, orthopnea, fast breathing, and episodes of “asthma” that did not improve with inhalers or other treatment) and cardiomyopathy or medial E/e' ratio. KCC-A scores were low in the study population overall (median 52; Q1:40, Q3: 61). We demonstrated a significantly lower KCC-A score among women with LVEF &amp;lt;50% (median 24; Q1: 15, Q3: 44) compared to women with LVEF ≥50% (median 54; Q1: 44, Q3: 61) p=0.02. Conclusions We showed no significant association between individual cardiovascular symptoms and cardiomyopathy in an obstetric population. However, we demonstrate for the first time that an adapted KCCQ-12 questionnaire for health status assessment could potentially identify women with a high-likelihood of cardiomyopathy during the peripartum period who may benefit from additional evaluation including echocardiography. Larger studies are needed to validate this finding. Funding Acknowledgement Type of funding sources: Foundation. Main funding source(s): This study was funded by a research grant from the Miami Heart Research Institute, Florida Heart Foundation. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health
An Infrastructure for the Dynamic Distribution of Web Applications and Services (2000)

This paper presents the design and implementation of an infrastructure that enables any Web application, regardless of its current state, to be stopped and uninstalled from a particular server, transferred to a new server, then installed, loaded, and resumed, with all these events occurring "on the fly" and totally transparent to clients. Such functionalities allow entire applications to fluidly move from server to server, reducing the overhead required to administer the system, and increasing its performance in a number of ways: (1) Dynamic replication of new instances of applications to several servers to raise throughput for scalability purposes, (2) Moving applications to servers to achieve load balancing or other resource management goals, (3) Caching entire applications on servers located closer to clients.
Nanometer-Sized Gold Particles Supported on SiO2by Deposition of Gold Sols from Au(PPh3)3Cl (2003)

An Au/SiO2 system with most of the metal particles less than 2.0 nm in size were prepared by deposition on silica of preformed gold sols derived from Au(PPh3)3Cl. In this form, it was inactive in the CO + O2 reaction at ca. 333 K, because of the presence of phosphine ligands on the surface of metal particles. The system became catalytically active in this reaction after treatment in O2 at 673 K, which also resulted in a slight sintering of the metal phase (mean size = 2.9 nm). By subsequent heating in H2 at 673 K, the mean size of gold particles increased up to 3.4 nm. Such particles exhibited a lower amount of step surface sites able to adsorb CO, but became more active in the CO + O2 reaction. This suggested that the reaction steps involving oxygen can occur more effectively on Au sites present on larger and smoother gold particles.
Parteien, Kandidaten, Themen: Stabilität und Wandel der Determinanten der Wahlentscheidung bei rheinland-pfälzischen Landtagswahlen (2010)

Die politische Landschaft in Rheinland-Pfalz hat sich in den letzten Jahrzehnten erheblich verändert. Einst galt das Bundesland als "christdemokratisches Stammland", in dem die CDU eine ähnliche Hegemonialstellung einnahm wie in Baden-Württemberg oder wie die CSU in Bayern. Ausdruck dieser Dominanz waren die überragenden Wahlergebnisse der Union, die von 1947 bis 1991 – also 44 Jahre in Folge – den Ministerpräsidenten stellte (vgl. Abbildung 1). Zwischen 1971 und 1987 wurde die CDU von den Wählern sogar mit einer absoluten Mehrheit im Mainzer Landtag ausgestattet. Nach herben Verlusten bei den Landtagswahlen 1987 und 1991 verloren die Christdemokraten die Macht an die SPD, der es in den Folgejahren gelang, Rheinland-Pfalz zu einer sozialdemokratischen Hochburg auszubauen. Den vorläufigen Höhepunkt dieser Entwicklung markierte die Landtagswahl 2006. Seither kann die SPD ohne Rücksicht auf einen Koalitionspartner regieren.
Gene Expression-Based Classification of Non-Small Cell Lung Carcinomas and Survival Prediction (2010)

The gene signatures identified are promising tools for histo-pathological classification of non-small cell lung cancer, and may improve the prediction of clinical outcome.
Efficient Conversion of Acetate to 3-Hydroxypropionic Acid by Engineered Escherichia coli (2018)

Acetate, which is an abundant carbon source, is a potential feedstock for microbial processes that produce diverse value-added chemicals. In this study, we produced 3-hydroxypropionic acid (3-HP) from acetate with engineered Escherichia coli. For the efficient conversion of acetate to 3-HP, we initially introduced heterologous mcr (encoding malonyl-CoA reductase) from Chloroflexus aurantiacus. Then, the acetate assimilating pathway and glyoxylate shunt pathway were activated by overexpressing acs (encoding acetyl-CoA synthetase) and deleting iclR (encoding the glyoxylate shunt pathway repressor). Because a key precursor malonyl-CoA is also consumed for fatty acid synthesis, we decreased carbon flux to fatty acid synthesis by adding cerulenin. Subsequently, we found that inhibiting fatty acid synthesis dramatically improved 3-HP production (3.00 g/L of 3-HP from 8.98 g/L of acetate). The results indicated that acetate can be used as a promising carbon source for microbial processes and that 3-HP can be produced from acetate with a high yield (44.6% of the theoretical maximum yield).
Prevalence of Cardiac Sarcoidosis in Patients Presenting with Monomorphic Ventricular Tachycardia (2013)

In this prospective study, four of 14 (28%) patients presenting with MMVT (without idiopathic VT, ischemic VT, or known sarcoidosis) had CS as the underlying etiology. Clinicians should consider screening for CS in patients with unexplained MMVT.
Inhibition of dual Ir gene-controlled T-lymphocyte proliferative response to poly (Glu56Lys35Phe9)n with anti-Ia antisera directed against products of either I-A or I-C subregion. (1978)

Previous studies have demonstrated that both the antibody and T-lymphocyte proliferative immune responses to poly(Glu53Lys36Phe11)n (GLphi) are under the control of two major histocompatibility-linked immune response (Ir) genes. One gene, termed Ir-GL phi-alpha, has been mapped to the I-C or I-E subregion of the major histocompatibility complex, while the other, termed Ir-GL phi-beta, has been mapped to the I-A subregion. In this paper we examine the effect of anti-I-region-associated (Ia) antisera on the T-lyphocyte proliferative response to GL phi. Antibodies directed against Ia antigens coded for by genes in either the I-A or I-C subregion were found to inhibit the proliferative response to GLphi. These results suggest that a function mediated by two Ir gene products can be blocked by anit-Ia antisera directed against either one, and thus, that both products are expressed on the cell surface.
3D Thermal Imaging: Fusion of Thermography and Depth Cameras (2014)

This work presents an approach to automatically create 3D thermal models using multi-perspective measurements with a multimodal camera system consisting of a thermal camera and a depth camera. Additional attributes such as color can also be added to the model. The paper centers its attention on the geometrical calibration of the cameras and the validation of the results. The design of an adequate calibration target is discussed and different options are evaluated. To expose the applicability of the approach two inspection tasks are used as examples.
Teleassistenz in einer alternden Gesellschaft. Von gedachten Szenarien zu realen Empfehlungen (PACITA Kurzbericht) (2015)

<i>Kurzbericht Ã¼ber den Ã¶sterreichischen Stakeholder-Szenario-Workshop im Rahmen des Projekts PACITA (Parliaments and Civil Society in Technology Assessment</i><br>Dieser Bericht basiert auf den Ergebnissen von Arbeitspaket 6 des EU-FP7-Projekts PACITA.
ChemInform Abstract: Synthesis and Properties of Bridged 2,2′‐Bithiazolium Salts. (1990)

Abstract 2,2'‐Bithiazole (I) is coupled with the polymethylene dihalides (II) to give the bridged bisthiazolium salts (III).
A Family of 1,1,3,3‐Tetraalkylguanidine (H‐TAG) Solvated Zinc Aryloxide Precatalysts for the Ring‐Opening Polymerization of rac‐Lactide (2010)

Abstract Reaction of [Zn(μ‐TAG){N(SiMe 3 ) 2 }] 2 {TAG = N=C[N(CH 2 CH 3 ) 2 N(CH 3 ) 2 ] (DEDMG), N=C{[NCH 2 CH 2 CH 2 C d H 2 ( N–C d )]N(CH 2 CH 3 ) 2 } (DEPYRG) and N=C{[NCH 2 CH 2 CH 2 CH 2 C e H 2 ( N–C e )]N(CH 2 CH 3 ) 2 } (DEPIPG)} with 2 equiv. of ethanol (EtOH) and 2 equiv. of HOAr {OAr = OC 6 H 3 (CMe 3 )‐2‐(CH 3 )‐6 (BMP) or OC 6 H 2 [C(CH 3 ) 3 ] 2 ‐2,6‐(CH 3 )‐4 (4MeDBP)} results in dizinc alkoxides with the general formula [Zn(μ‐OEt)(OAr)(H‐TAG)] 2 ( 1 – 3 ). Et 2 Zn was additionally treated with 2 equiv. of 1,1,3,3‐tetramethylguanidine (H‐TMG) and H‐BMP or HOC 6 H 3 (C 6 H 5 ) 2 ‐2,6 to yield [Zn(BMP) 2 (H‐TMG) 2 ] ( 4 ) and [Zn{OC 6 H 3 (C 6 H 5 ) 2 ‐2,6} 2 (H‐TMG) 2 ] ( 5 ). Complexes 1 , 2 , 4 , and 5 were characterized by single‐crystal X‐ray diffraction. Polymerization of rac ‐lactide with 1 – 5 and [Zn(μ‐OMe)(4MeDBP)(H‐TMG)] 2 ( 6 ) were found to generate polylactide (PLA). The bulk powders for all complexes were found to be in agreement with the crystal structures based on elemental analyses, FTIR spectroscopy, and 1 H and 13 C NMR spectroscopic studies.
An approximate max-flow min-cut theorem for uniform multicommodity flow problems with applications to approximation algorithms (1988)

A multicommodity flow problem is considered where for each pair of vertices (u, v) it is required to send f half-units of commodity (u, v) from u to v and f half-units of commodity (v, u) from v to u without violating capacity constraints. The main result is an algorithm for performing the task provided that the capacity of each cut exceeds the demand across the cut by a Theta (log n) factor. The condition on cuts is required in the worst case, and is trivially within a Theta (log n) factor of optimal for any flow problem. The result can be used to construct the first polylog-times optimal approximation algorithms for a wide variety of problems, including minimum quotient separators, 1/3-2/3 separators, bifurcators, crossing number, and VLSI layout area. It can also be used to route packets efficiently in arbitrary distributed networks.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Hierarchical Language-based Representation of Events in Video Streams (2003)

We aim to define an event ontology that allows natural representation of complex spatio-temporal events common in the physical world by a composition of simpler events. The events are abstracted into three hierarchies. Primitive events are defined directly from the mobile object properties. Single-thread composite events are a number of primitive events with temporal sequencing. Multi-thread composite events are a number of single-thread events with temporal/ spatial/logical relationships. This hierarchical event representation naturally leads to a language description of the events. We define an Event Recognition Language (ERL) which allows the users to define the events of interest conveniently without interacting with the low level processing in the program. We will also briefly mention some approaches to compute the proposed representation.
Enantioselective Total Synthesis of Eicosanoid and Its Congener, Using Organocatalytic Cyclopropanation, and Catalytic Asymmetric Transfer Hydrogenation Reactions as Key Steps (2008)

An enantioselective unified strategy for the syntheses of the oxylipin class of natural products was accomplished. Our strategy relies on three catalytic steps: (a) organocatalytic cyclopropanation, (b) the catalytic asymmetric transfer hydrogenation (CATHy) reaction, and (c) the Nozaki-Hiyama-Kishi reaction.
Long‐period lunar fortnightly and monthly ocean tides (1998)

Long‐period lunar fortnightly (Mf) and monthly (Mm) tides in the global oceans are of particular interest to geophysicists because of their impact on the Earth's rotation, and they are of interest to oceanographers from the point of view of the response characteristics of the global oceans to low‐frequency forcing. Long‐period tides have long been quite controversial, but precision altimetry is providing an accurate means of measuring and modeling them in the global oceans. Here we describe Mf and Mm tides in the global oceans extracted from a 1° barotropic global hydrodynamic tidal model, which assimilates ocean tides estimated from cycles 10–130 of TOPEX altimetric data by an empirical tide model. The model results enable a better understanding of the energetics of these tides. Compared to the short‐period ocean tides, which dissipate a total of roughly 3490 GW of lunisolar gravitational energy, the dissipation rates for Mf and Mm, 0.369 and 0.023 GW, respectively, are quite insignificant from the point of view of the dissipation of tidal energy in the global oceans. Their energy content is also low, 0.381 and 0.049 PJ, respectively (compared to 580 PJ in short‐period tides). Also compared to the high quality factor Q values for short‐period tides (∼23 for semidiurnal and ∼13 for diurnal), the Q values for these tides are 5.9 and 6.2 for Mf and Mm, respectively. The corresponding unassimilated model Q value is 5.8 for both. These Q values correspond to a decay timescale of the order of a period and hence indicate that unlike its response to short‐period tidal forcing, the oceanic response to barotropic forcing at these low frequencies is like a heavily damped system. They are also consistent with the low values of Q (∼5.5) observed in the global oceans on timescales of several days. The relative potential energy to kinetic energy ratios for Mf and Mm tides (0.59 and 2.91 for assimilated and 0.83 and 3.20 for unassimilated, for Mf and Mm, respectively) are consistent with the dynamics of long‐wavelength Rossby waves. At amplitudes of ∼0.115 ms in universal time, UT1, for both Mf and Mm, the impact of these long‐period tides on the length of day fluctuations of the Earth is considerable.
Thermally activated domain wall motion in [Co/Ni](111) superlattices with perpendicular magnetic anisotropy (2015)

This article presents field-induced magnetization dynamics in a [Co/Ni] superlattice exhibiting strong perpendicular magnetic anisotropy using Kerr microscopy. Domain wall velocity is reported within thermally activated, transitory and flow dynamical regimes. At low field, the thermally activated regime is characterized by dendritic domain growth that differs from the creep mechanism usually observed for the interaction of domains wall with a 2D random pinning potential for layers grown by sputtering. This result is explained by the epitaxial nature of the [Co/Ni] superlattices involving a single-type defect. The transition from the thermally activated to the flow regime is characterized by a reduction of the density of non-reversed domains which exist after domain wall displacement. The effect of spin transfer torque on domain wall is also discussed.
Differential D-glucose requirements of the general amino-acid permease and protein synthesis in Saccharomyces cerevisiae var. ellipsoideus. (1990)

The dependence of the general aminoacid permease and protein synthesis on the availability of D-glucose as energy source was studied. Stimulation by the sugar was immediate once added to the cell suspensions and seems to be mediated by energy derived directly from glycolysis. The general aminoacid permease was saturated linearly with D-glucose whereas protein synthesis was saturated sigmoidealy requiring much higher concentration of the sugar than the general aminoacid permease.
Lateral costal artery: Accessory thoracic vessel of clinical interest (2004)

The lateral costal artery (LCA), a supernumerary branch of the internal thoracic artery (ITA), occurs in several ethnic groups on one side of the thorax or on both, in 15-30% of cases. It has been considered responsible for the "steal-syndrome" of the coronary blood after coronary artery bypass grafting and it used occasionally for myocardial revascularization. To clarify its functional significance, an interpretation based on our findings and human and comparative anatomy and embryology has been attempted. We report on a case where a right LCA of about 2 mm in caliber, rising from the ITA 2.5 cm below the subclavian, coursed as far as the 4th intercostal space for a distance of 13 cm after the anterior axillary line. Anastomosing with the intercostal arteries, it can act as a blood derivative circuit of the thoracic wall. Embryologically, this artery, like the normal parietal arteries of the trunk, might form a longitudinal channel connecting the intersegmental arteries. In mammals having a thoracic cage transversely restricted (quadrupeds), the ITA is more lateral than in primates having a circular thorax, and gives off a ventral branch toward the sternum. It might be hypothesized that the sternal branch occurring in quadrupeds, undergoing adaptation to the thoracic shape of primates, may become the main trunk of the ITA, whereas the LCA may be the remnant of the ITA of quadrupeds. Because the LCA ran partly along the "milk line" of humans, it might be regarded as a supernumerary mammary artery.
Factors contributing to ribavirin‐induced anemia (2004)

Careful administration is necessary in patients > or =60 years old, in female patients, and in patients receiving a ribavirin dose of 12 mg/kg or more. Patients who experience a fall in hemoglobin concentrations of 2 g/dL or more at week 2 after the start of treatment should be monitored with particular care.
A novel neutralizing monoclonal antibody targeting the N-terminal domain of the MERS-CoV spike protein (2017)

This corrects the article DOI: 10.1038/emi.2017.18.
Syntactical and Semantical Description of Video Sequences (1999)

Archiving, processing, and intelligent retrieval of digital video sequences can be efficiently solved by a high-level representation of video sequences. We describe a complete system for encoding the contents of video sequences based on their syntactical and semantical description. Our techniques are built on two phases: analysis and synthesis. The analysis phase involves the automatic generation of a syntactical structure using image and image-sequence analysis, image understanding as well as text recognition. Moreover, the syntactical description of images will be completed by a semantical understanding of video sequences. The full representation of video sequences will be generated during the synthesis phase by combining results from the analysis phase. Our developed prototype system is planned to be integrated into the co-operative work of a TV-team of the TV-station “Radio Bremen”.Additionally, we describe some special functionality: scene analysis by clustering of video sequences with the aim of identifying a typical video genre. The latter is an useful approach for automatic trailer generation and for intelligent video editing as add-on for a video-cut-system.
Learning Simpler Language Models with the Differential State Framework (2017)

Learning useful information across long time lags is a critical and difficult problem for temporal neural models in tasks such as language modeling. Existing architectures that address the issue are often complex and costly to train. The differential state framework (DSF) is a simple and high-performing design that unifies previously introduced gated neural models. DSF models maintain longer-term memory by learning to interpolate between a fast-changing data-driven representation and a slowly changing, implicitly stable state. Within the DSF framework, a new architecture is presented, the delta-RNN. This model requires hardly any more parameters than a classical, simple recurrent network. In language modeling at the word and character levels, the delta-RNN outperforms popular complex architectures, such as the long short-term memory (LSTM) and the gated recurrent unit (GRU), and, when regularized, performs comparably to several state-of-the-art baselines. At the subword level, the delta-RNN's performance is comparable to that of complex gated architectures.
Miconazole, a pharmacological barrier to skin fungal infections (2012)

MCZ's wide spectrum of activity appears noteworthy. The full pharmacological profile of MCZ indicates its fungistatic profile through its effect on ergosterol biosynthesis. In addition, it exhibits a fungicidal effect against a number of fungal species, due to hydrogen peroxide accumulation. MCZ is characterized by high safety, efficacy and versatility, and a unique, multifaceted nature of activity in the treatment of dermatomycoses.
A miniature powerplant for very small, very long range autonomous aircraft. Final report (1999)

The authors have developed a new piston engine offering unprecedented efficiency for a new generation of miniature robotic aircraft. Following Phase 1 preliminary design in 1996--97, they have gone forward in Phase 2 to complete detail design, and are nearing completion of a first batch of ten engines. A small-engine dynamometer facility has been built in preparation for the test program. Provisions have been included for supercharging, which will allow operation at ceilings in the 10,000 m range. Component tests and detailed analysis indicate that the engine will achieve brake-specific fuel consumption well below 300 gm/kWh at power levels of several hundred watts. This level of performance opens the door to development of tabletop-sized aircraft having transpacific range and multi-day endurance, which will offer extraordinary new capabilities for meteorology, geomagnetic, and a variety of applications in environmental monitoring and military operations.