gebhart/patrepeval huggingface dataset:
Central Catecholamines and Alpha-Adrenoceptors in Acute Hypertension Induced by Intracerebroventricular Hypertonic Saline (1987)

We measured the tissue content of catecholamines and the numbers and affinities of alpha 1- and alpha 2-adrenergic receptors in specific areas of the hypothalamus and medulla oblongata of rats treated with intracerebroventricular microinjection of hypertonic saline, in comparison to controls treated with an equal volume of iso-osmolar dextrose solution. Rats given 20 microliter of 4% NaCl into the lateral ventricle showed an average rise in blood pressure of 14 +/- 2 mmHg and a decrease in heart rate of 63 +/- 11 beats/min (P less than 0.001 for both), associated with dopamine suppression in the anteroventral area of the third ventricle (AV3V) and increased concentrations of dopamine in the C2 region of the medulla and of epinephrine in the area postrema. Affinities of medullary alpha 2-adrenoceptors were decreased in the saline-treated rats, whereas the number of receptors tended to be higher. It is suggested that sodium may produce its pressor effect by diminishing the affinity of central alpha 2-adrenoceptors for neurotransmitters, resulting in disinhibition of certain sympathoinhibitory neurons and increased sympathetic outflow.
An Electric Field Meter for Use on Airplanes (1948)

An instrument capable of measuring the magnitude and polarity of electric fields at selected regions on an airplane in flight is described. The device covers a range of from 5 volts per cm to 4000 volts per cm in four steps with linear scales and is powered from a 28-volt d.c. supply.
Angle-sensitive pixel design for wavefront sensing (2013)

Conventional image sensors are only responsive to the intensity variation of the incoming light wave. By encoding the wavefront information into the balanced detection scheme, we demonstrate an image sensor pixel design that is capable to detect both the local intensity and wavefront information simultaneously. With the full compatibility to the CMOS fabrication process, the proposed pixel design can benefit a variety of applications, including phase microscopy, lensless imaging and machine vision.
Embedding Label Structures for Fine-Grained Feature Representation (2015)

Recent algorithms in convolutional neural networks (CNN) considerably advance the fine-grained image classification, which aims to differentiate subtle differences among subordinate classes. However, previous studies have rarely focused on learning a fined-grained and structured feature representation that is able to locate similar images at different levels of relevance, e.g., discovering cars from the same make or the same model, both of which require high precision. In this paper, we propose two main contributions to tackle this problem. 1) A multi-task learning framework is designed to effectively learn fine-grained feature representations by jointly optimizing both classification and similarity constraints. 2) To model the multi-level relevance, label structures such as hierarchy or shared attributes are seamlessly embedded into the framework by generalizing the triplet loss. Extensive and thorough experiments have been conducted on three fine-grained datasets, i.e., the Stanford car, the car-333, and the food datasets, which contain either hierarchical labels or shared attributes. Our proposed method has achieved very competitive performance, i.e., among state-of-the-art classification accuracy. More importantly, it significantly outperforms previous fine-grained feature representations for image retrieval at different levels of relevance.
Transfusion-associated HIV infection in Mexico related to paid blood donors; HIV epidemic (2004)

The objective of the study was to describe the clinical, epidemiological profile and conditional incubation period in a group of transfusion-associated HIV-infected (TAHI) patients seen in five national tertiary care centres in Mexico from 1983 to April 1998. Date of transfusions, AIDS diagnoses, opportunistic infections and malignancies were collected. The incubation period was estimated through a non-parametric conditional analysis. One hundred and fifty-seven TAHI cases were analysed. The frequency of TAHI by year of transfusion was: 0.6% in 1980 and 1981, 4.5% in 1984, 22.4% in 1985, 54.5% in 1986, 10.3% in 1987, 0.6% in 1988, 1.9% in 1989 and 1990, 1.3% in 1993 and 0.6% in 1994 and 1996. The median incubation period was 4.3 years. A well-defined epidemic period of HIV-infection among blood-recipients was identified that coincided with the HIV-epidemic among paid donors. TAHI patients in Mexico developed AIDS in a shorter time than that described for other populations.
The First Highly Enantioselective Homogeneously Catalyzed Asymmetric Reductive Amination:  Synthesis of α-N-Benzylamino Acids (2003)

High-throughput screening considering a library of 96 chiral P-ligands involved in two types of Rh(I) complexes was used for the identification of homogeneous catalysts for the highly enantioselective reductive amination of alpha-keto acids with benzylamine. After optimization of the reaction conditions and scale-up with a cationic Rh-Deguphos catalyst, a range of chiral alpha-amino acids could be produced by this new reaction in good yield and by up to 98% ee.
HPLC Analysis of Oxidation Hair Dyes in Permanent Hair Colorants (1994)

Abstract The reversed-phase liquid chromatographic separation of several hair dyes (diamines, aminophenols, phenols, etc.), using mobile phases containing 1,8-diaminoctane as new amine modifier and sodium heptansulfonate, is described. The combined effect of the amine and of the alkylsulfonate enabled very good separation of all the dyes studied. The proposed chromatographic system was found to be selective, rugged and therefore suitable for the reliable quality control of commercial permanent colorants. A preliminary solid phase extraction (SPE) procedure using SCX sorbents, was found useful to enhance detectability of low concentrated dyes and to isolate phenol compounds from the basic dyes.
Heat loss from deer mice (Peromyscus): evaluation of seasonal limits to thermoregulation (1986)

This paper investigates the influence of seasonal adaptations to thermoregulatory heat loss for deer mice (Peromyscus) during summer and winter. A general, mechanistic model of heat transfer through fur was evaluated for the structural properties of the fur of deer mice. The model was validated against heat production determined from mice exposed to a range of radiative (wall) temperatures (tr) at air temperatures (ta) of 15, 27 and 34 degrees C. Calculated heat loss from the appendages was subtracted from the measured heat production to yield heat loss from the furred torso. This calculated torso heat loss agreed closely with the predicted fur heat loss for all conditions, as shown by a regression slope near 1 (0.99). Simulations using models of fur and appendage heat loss reveal that the winter increase in thermogenic (heat production) capacity has a greater effect than changes in fur properties in expanding the limits to thermoregulation. Both wind and a clear night sky increase heat loss and can limit thermoregulation to air temperatures above those found in deer mice habitats during winter (-25 degrees C). Thus, despite seasonal adaptations, these simulations indicate that thermoregulation is not possible under certain winter conditions, thereby restricting deer mice to within the protected environment of the leaf litter or snow tunnels.
Identification of Serum Biomarkers in Brain-Injured Adults: Potential for Predicting Elevated Intracranial Pressure (2008)

Brain injury biomarkers may have clinical utility in stratifying injury severity level, predicting adverse secondary events or outcomes, and monitoring the effectiveness of therapeutic interventions. As a biomarker source, serum offers several advantages over cerebrospinal fluid (CSF), including ease of accessibility and reduced risk to the patient. We screened pooled serum samples obtained from 11 severely injured traumatic brain injury (TBI) patients (Glasgow Coma Scale [GCS] <or= 8) and 11 age-, sex- and race-matched volunteers. Two time points-41.5 +/- 4.9 h and 66.3 +/- 6.6 h post-injury-were chosen for the initial screening analysis. Samples were immunodepleted for 12 highly abundant serum proteins, and then labeled with mass-balanced isobaric tags (iTRAQ), and analyzed by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Identification and quantification of 2455 iTRAQ-labeled peptides that mapped to 160 proteins revealed 31 candidate biomarkers whose serum abundance was altered after injury. Changes in three candidate biomarkers (serum amyloid A, [SAA], c-reactive protein [CRP], retinol binding protein 4 [RBP4]) were verified using independent TBI and healthy volunteer serum samples. Receiver operating characteristic (ROC) curve analysis of CRP and SAA indicated they were robust indicators of injury even at very acute time points. Analysis of serum RBP4 levels at 24-36 h post-injury indicates it may predict subsequent increases in intracranial pressure (ICP) with a sensitivity of 86% and specificity of 88% at 11.6 mug/mL [n = 7, ICP < 20 mm Hg; n = 8, ICP > 25 mm Hg). Our results support the use of serum as a source for discovery of TBI biomarkers, and indicate that serum biomarkers may have utility for predicting secondary pathologies (e.g., elevated ICP) associated with TBI.
A review on energy management, operation control and application methods for grid battery energy storage systems (2019)

Energy storage is the key means to improving the flexibility, economy and security of the power system. It is also important in promoting new energy consumption and energy Internet. Therefore, energy storage expected to support distributed power and micro-grid, promote open sharing and flexible trading of energy production and consumption, and realize multi-functional coordination. In recent years, with the rapid development of the battery energy storage industry, its technology has shown the characteristics and trends for large-scale integration and distributed applications with multi-objective collaboration. As a grid-level application, energy management systems (EMS) of battery energy storage system (BESS) were deployed at utility control centers as an important component of power grid management in real-time. Based on the analysis of the development status of BESS, this paper introduced its application scenarios such as reduction of power output fluctuations, accordance to the output plan at renewable energy generation side, power grid frequency adjustment, power flow optimization at power transmission side, and distributed and mobile energy storage system at power distribution side. The studies and application status of BESS in recent years were reviewed. The energy management, operation control methods, and application scenes of large-scale BESS were also prospected in the study.
Matrix Factorization with Interval-Valued Data (2020)

With many applications relying on multi-dimensional datasets for decision making, matrix factorization (or decomposition) is becoming the basis for many knowledge discovery and machine learning tasks, from clustering, trend detection, anomaly detection, to correlation analysis. Unfortunately, a major shortcoming of matrix analysis operations is that, despite their effectiveness when the data is scalar, these operations become difficult to apply in the presence of non-scalar data, as they are not designed for data that include non-scalar observations, such as intervals. In this paper, we propose matrix decomposition techniques that consider the existence of interval-valued data. We show that naive ways to deal with such imperfect data may introduce errors in analysis and present factorization techniques that are especially effective when the amount of imprecise information is large.
OsNBL3, a mitochondrion‐localized pentatricopeptide repeat protein, is involved in splicing nad5 intron 4 and its disruption causes lesion mimic phenotype with enhanced resistance to biotic and abiotic stresses (2021)

Lesion mimic mutants are used to elucidate mechanisms controlling plant responses to pathogen attacks and environmental stresses. Although dozens of genes had been functionally demonstrated to be involved in lesion mimic phenotype in several plant species, the molecular mechanisms underlying the hypersensitive response are largely unknown. Here, a rice (Oryza sativa) lesion mimic mutant natural blight leaf 3 (nbl3) was identified from T-DNA insertion lines. The causative gene, OsNBL3, encodes a mitochondrion-localized pentatricopeptide repeat (PPR) protein. The nbl3 mutant exhibited spontaneous cell death response and H<sub>2</sub> O<sub>2</sub> accumulation, and displayed enhanced resistance to the fungal and bacterial pathogens Magnaporthe oryzae and Xanthomonas oryzae pv. oryzae. This resistance was consistent with the up-regulation of several defence-related genes; thus, defence responses were induced in nbl3. RNA interference lines of OsNBL3 exhibited enhanced disease resistance similar to that of nbl3, while the disease resistance in overexpression lines did not differ from that of the wild type. In addition, nbl3 displayed improved tolerance to salt, accompanied by up-regulation of several salt-associated marker genes. OsNBL3 was found to mainly participate in the splicing of mitochondrial gene nad5 intron 4. Disruption of OsNBL3 leads to the reduction in complex I activity, the elevation of alternative respiratory pathways and the destruction of mitochondrial morphology. Overall, the results demonstrated that the PPR protein-coding gene OsNBL3 is essential for mitochondrial development and functions, and its disruption causes the lesion mimic phenotype and enhances disease resistance and tolerance to salt in rice.
Saline nasal irrigation: Its role as an adjunct treatment. (2003)

Nasal irrigation is a simple, inexpensive treatment that relieves the symptoms of a variety of sinus and nasal conditions, reduces use of medical resources, and could help minimize antibiotic resistance.
Default Mode and Fronto-Parietal Network Associations with IQ Development Across Childhood in Autism (2021)

Abstract Background: Intellectual disability affects approximately one third of individuals with autism spectrum disorder (autism), yet a major unresolved question remains concerning the neurobiology that differentiates autistic individuals with and without intellectual disability. IQ is highly variable during childhood. We previously identified subgroups of autistic children with different trajectories of intellectual development from early childhood (2-3½ yeas) up to middle childhood (9-12 years): (a) Persistently-High: Individuals whose intelligence quotients (IQs) remained in the average or better range during this period, (b) Persistently-Low: Individuals whose IQs remained in the range of intellectual disability (IQ &lt; 70) throughout development, and (c) Changers: Individuals whose IQs began in the range of intellectual disability but increased to the borderline or normal IQ range by middle childhood. In the present research, we sought to identify neurobiology that differentiates these trajectory-defined groups within our autism cohort in two brain networks with established links to intellectual functioning and its impairment in (1) the frontoparietal network (FPN), and (2) the default mode network (DMN). Methods: We conducted multivariate distance matrix regression (MDMR) and effect size analyses to examine the volumes of 22 brain regions (11 regions x 2 hemispheres) within the FPN and 24 (12 regions x 2 hemispheres) within the DMN in 48 Persistently-High (18 female), 108 Persistently-Low (32 female), and 109 Changers (39 female) using structural MRI that had been acquired at baseline, and IQ measurements from up to three time points spanning early to middle childhood (Mean Age Time 1: 3.2 years; Time 2: 5.4 years; Time 3: 11.3 years). FPN and DMN network regions of interest were defined on the basis of the large-scale networks defined in Smith et al., (2009). Results: Changers exhibited different DMN network structure from both Persistently-Low and Persistently-High trajectory groups at baseline, but the Persistently-High did not differ from the Persistently-Low group, suggesting that DMN structure may be an early predictor for change in IQ trajectory across childhood. In contrast, Persistently-High exhibited differences in the FPN from both Persistently-Low and Changers groups at baseline, suggesting a difference related more to concurrent IQ and the absence of intellectual disability. Conclusions: Within autism, DMN structure at baseline may differentiate individuals with persistently low IQ from those with more transitory low IQ that improves to the borderline range or better through early childhood, potentially indicating compensatory mechanisms which may be targeted by future interventions. The brain structure differences between these three IQ-based subgroups may be indicative of distinct neural underpinnings of autism phenotypic subtypes.
Vapor−Liquid Equilibria for Mixtures Containing cis-But-2-ene, 1,3-Butadiene, and N-Formylmor-pholine Measured with the Vangeli Equilibrium Still (1999)

ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionORIGINAL ARTICLEThis notice is a correctionVapor−Liquid Equilibria for Mixtures Containing cis-But-2-ene, 1,3-Butadiene, and N-Formylmor-pholine Measured with the Vangeli Equilibrium StillAlessandro VetereCite this: J. Chem. Eng. Data 1999, 44, 5, 1103Publication Date (Web):July 29, 1999Publication History Published online29 July 1999Published inissue 1 September 1999https://pubs.acs.org/doi/10.1021/je9904762https://doi.org/10.1021/je9904762correctionACS PublicationsCopyright © 1999 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views235Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (10 KB) Get e-Alertsclose Get e-Alerts
The Mortality of an E-Commerce Formula for Success (2006)

Commerce One (or C1) developed software systems enabling companies to transform their purchasing interactions into real-time trading networks. Commerce One acquired the e-business budgets of many Fortune 1000 companies. On December 28, 1999, as a highflier in the dot-com era, Commerce One sharply increased to $1,655 (a split-adjusted) per share. In the constellation of corporations, Commerce One was a bright star. Soon after, diminished enthusiasm for the company and its nascent business-to-business (B2B) software industry deflated its stock value. On October 15, 2004, CMRCQ, a new symbol for Commerce One after being removed from the NASDAQ in July 2004, plummeted to $0.03 per share. In the period of devaluation of the stock market that followed the dot-com era, Commerce One became extinct. This article will examine the rise and fall of Commerce One by exploring the industry backdrop, the key events in the company’s history, and the challenges that ultimately overcame it.
SE4 Automotive Signal Processing Technologies (2007)

Presents panel discussions from the conference proceedings.
A Compartmental Pharmacokinetic Evaluation of Long-Acting Rilpivirine in HIV-Negative Volunteers for Pre-Exposure Prophylaxis (2014)

Rilpivirine long-acting (RPV-LA) is a parenteral formulation enabling prolonged plasma exposure. We explored its multiple-compartment pharmacokinetics (PK) after a single dose, for pre-exposure prophylaxis. Sixty-six HIV-negative volunteers were enrolled: women received an intramuscular dose of 300, 600, or 1,200 mg, with plasma and genital levels measured to 84 days postdose; men receiving 600 mg had similar PK determined in plasma and rectum. Ex vivo antiviral activity of cervicovaginal lavage (CVL) was also assessed. After a single dose, RPV concentrations peaked at days 6-8 and were present in plasma and genital-tract fluid to day 84. Vaginal and male rectal tissue levels matched those in plasma. At the 1,200 mg dose, CVL showed greater antiviral activity, above baseline, at days 28 and 56. All doses were well tolerated. All doses gave prolonged plasma and genital-tract rilpivirine exposure. PK and viral inhibition of repeated doses will be important in further dose selection.
Photochemical approaches to conversion of light to electricity or fuel. Progress report, December 1, 1992--November 30, 1993 (1993)

Objective is to understand photochemical and photophysical processes, and to develop photochemical systems for converting light to electricity or fuel: Orientation of multi-component redox polymers on surfaces; excited state electron transport in multi-component molecules prepared via ring opening metathesis polymerization; molecular materials for solid state photovoltaics. Rhenium complexes were covered.
Surfactant-Mediated Lithium Orthosilicate Composite Enables Rapid High-Temperature CO2 Absorption (2021)

A novel surfactant-assisted approach to preparing a nanostructured lithium orthosilicate (LOS) has been developed by adding a polyether amine surfactant to aqueous citrate sol–gel. The ratio of surfactant to SiO2 was critical to producing an LOS that is stable to carbonation/decarbonation cycles. Preferred LOS compositions sorb 26 wt % CO2 within 1 min from a 50 vol % CO2/N2 stream and show no observed loss in a 33 wt % working capacity in 1 h isothermal steam cycles. The novel synthetic approach generates a product-like precursor phase with nanoscale domains of lithium metasilicate and lithium carbonate stabilized by a carbonaceous component that originates from the degradation of citrate and surfactant species. This composition is required to achieve an LOS with properties enabling sorption-enhanced catalysis. Physically meaningful rate constants and diffusivities are provided by a piecewise adaptation of the Ishida and Wen core–shell model, confirming faster reaction and diffusion kinetics for these high-performing LOS. An overall working hypothesis of key results helps to explain robustness in sorption cycling and suggests the advantages of a product-focused sorbent design.
Coronary artery revascularization followed by single-lung transplantation in a patient with combined end-stage idiopathic pulmonary fibrosis and left main coronary artery stenosis. (1995)

Single-lung transplantation has been used successfully in patients who have idiopathic pulmonary fibrosis; however, coronary artery disease is often considered a contraindication for lung transplantation in such patients. We report the case of a 53-year-old man with idiopathic pulmonary fibrosis in whom left main coronary artery stenosis was found incidentally during pretransplant evaluation. The patient was treated successfully with elective coronary artery bypass grafting, followed by left single-lung transplantation 35 days later.