gebhart/patrepeval huggingface dataset:
High-Performance Humidity Sensing in π-Conjugated Molecular Assemblies through the Engineering of Electron/Proton Transport and Device Interfaces (2022)

The development of systems capable of responding to environmental changes, such as humidity, requires the design and assembly of highly sensitive and efficiently transducing elements. Such a challenge can be mastered only by disentangling the role played by each component of the responsive system, thus ultimately achieving high performance by optimizing the synergistic contribution of all functional elements. Here, we designed and synthesized a novel [1]benzothieno[3,2-<i>b</i>][1]benzothiophene derivative equipped with hydrophilic oligoethylene glycol lateral chains (OEG-BTBT) that can electrically transduce subtle changes in ambient humidity with high current ratios (>10<sup>4</sup>) at low voltages (2 V), reaching state-of-the-art performance. Multiscale structural, spectroscopical, and electrical characterizations were employed to elucidate the role of each device constituent, viz., the active material's BTBT core and OEG side chains, and the device interfaces. While the BTBT molecular core promotes the self-assembly of (semi)conducting crystalline films, its OEG side chains are prone to adsorb ambient moisture. These chains act as hotspots for hydrogen bonding with atmospheric water molecules that locally dissociate when a bias voltage is applied, resulting in a mixed electronic/protonic long-range conduction throughout the film. Due to the OEG-BTBT molecules' orientation with respect to the surface and structural defects within the film, water molecules can access the humidity-sensitive sites of the SiO<sub>2</sub> substrate surface, whose hydrophilicity can be tuned for an improved device response. The synergistic chemical engineering of materials and interfaces is thus key for designing highly sensitive humidity-responsive electrical devices whose mechanism relies on the interplay of electron and proton transport.
APOPLASTIC LEVELS OF HYDROXYL RADICALS IN FOUR DIFFERENT APPLE CULTIVARS ARE ASSOCIATED WITH SEVERITY OF CUT-EDGE BROWNING (2005)

Past research has shown that severity of cut-edge browning in apples used to make fresh slices is highly dependent on the cultivar. 'Ambrosia' and 'SPA343' are resistant to browning, while 'Delicious' and 'Spartan' are very susceptible. Prior experiments have shown a relationship of browning severity with superoxide dismutase/peroxidase activity ratios and peroxide contents in the apoplast. However, peroxides themselves are not sufficiently active to cause lipid peroxidation and membrane degradation. Lipid peroxidation and membrane degradation are the processes that lead to the intermingling of phenolics and polyphenol oxidase, thus leading to the initiation of browning reactions. Hydroxyl radicals can directly initiate lipid peroxidation and they are formed in vivo through the interaction of the superoxide anion with hydrogen peroxide. This research used a newly-developed method to measure hydroxyl radicals in vivo to evaluate whether hydroxyl radical accumulation in the apoplast could be associated with severity of cut-edge browning. The results clearly show that apoplastic levels of hydroxyl radical are closely related to the severity of cut-edge browning, whereas peroxide levels, water soluble antioxidants and phenols are not. A model is presented to explain the results.
Discrimination of Aerobic Endospore-forming Bacteria via Electrospray-Ionization Mass Spectrometry of Whole Cell Suspensions (2001)

Direct injection electrospray ionization mass spectrometry (ESI-MS) without prior analyte separation was investigated for the analysis of whole cell suspensions of bacteria. Thirty-six strains of aerobic endospore-forming bacteria, consisting of six Bacillus species and one Brevibacillus species, were studied
Comparison of thermal and microwaveassisted plasma sintering of nickel–diamond composites (2010)

There is considerable interest in processing technologies which can lead to more energy efficient sintering of metal powders. Microwave sintering has recently been shown to reduce energy usage as the volumetric heating process is considerably more efficient than resistance heating. RF plasma sintering meanwhile has been shown to deliver heat via uniform excitation of the processing gas resulting in ion bombardment of the workpiece. In this study the use of a rapid, novel microwave-assisted plasma sintering (MaPS) technology for processing of nickel-diamond metal matrix composites is evaluated. Nickel powder and polycrystalline diamond were mixed to prepare 20 mm discs under uniaxial compaction pressures of 100, 200 and 300 MPa. The discs were fired in a low pressure microwave plasma under a hydrogen atmosphere. For comparison, discs were also sintered using conventional tube furnace firing. The MaPS sintering is very rapid with full disc strength of >1000N, based on 3-point bend tests, being achieved within 10 minutes compared with 8 hours for furnace treatment. This study demonstrates that the microwave-assisted plasma sintered discs produced similar or superior performance to discs fired using furnace firing conditions but with sintering cycle time reduced by up to 95%.
Fungemia in a cancer patient caused by fluconazole-resistantCryptococcus laurentii (2002)

We report the recent isolation of Cryptococcus laurentii from the blood of a patient given the diagnosis of ganglioneuroblastoma. The organism was identified using physiological and molecular characteristics, including morphology, carbohydrate and nitrate assimilation, urease activity, inability to form melanin on appropriate media, positive staining with diazonium blue B and sequence analysis of the D1/D2 domain of 26S ribosomal DNA. The isolate was resistant to fluconazole and 5-fluorocytosine using both the Etest and a broth microdilution assay. Repeated recovery of the organism from different blood cultures, and the patient's good response to treatment with amphotericin B support its etiological role. C. laurentii has rarely been implicated as a cause of clinically significant infections. The identity of reported isolates has not always been adequately documented, and some appear to have been isolated from lesions caused by Cryptococcus neoformans, emphasizing the true rarity of disease due to this fungus.
Optically variable films, pigments, and inks (1990)

Optically variable thin film coatings have been prepared on rolls of polyester film by depositing thin multi-layers in a vacuum roll coater. Such coatings can be removed from the polyester film and ground into optically variable pigments for printing inks. Various printing inks including gravure, flexographic, and Intaglio inks have been prepared from these pigments, and printed images using these inks have been obtained from commercial printing presses. These optically variable systems have been used on various security documents to prevent counterfeiting with color copiers. Unique colors, color shifting effects, and other optical properties have been obtained by combining non-optically variable pigment and dyes with this light interference pigment. The merits of this new ink relative to other optically variable systems are color uniformity, print quality, its ready use on existing printing presses, and high security.
On Some Improvements of Ionization Gauges of the Extractor Type for the Measurement of Extreme High Vacuum. (1996)

The extractor principle seems to be the most useful principle for the measurement of xhv. Even simple extractor systems are able to discriminate between ions generated in the gas phase and ESD ions produced at the grid surface. According to our calculations the modified extractor gauge developed in our institute is less influenced by ESD ions than the extractor gauge suggested by Redhead. By experiments was demonstrated, that a gold coating of the anode reduces the ESD effect too.In the case of an extractor gauge the light of the hot filament gauge has a small influence on the ion current in the xhv range. The influence of the vapor pressure of the cathode material on the ion current can be reduced by the use of activated cathodes operating at low temperatures. These results were obtained experimentally.Topics of a further development are the problems of the reduction of the outgassing rate and the fast and convinient measurement of extremely low ion currents. The use of electron multipliers complicates the degassing process and the electronicequipment for the measurement of these low ion currents.
Cost-based prevention of violations of service level agreements in composed services using self-adaptation (2012)

Providers of composite Web services face the challenge of having to comply to SLAs, which are agreements governing the minimum performance that customers can expect from a composite service. In this work, a framework for optimizing adaptations of service compositions with regards to SLA violations has been developed. The framework, dubbed PREvent (Prediction and Prevention of SLA Violations Based on Events), uses techniques from the areas of machine learning and heuristic optimization to construct models for prediction of SLA violations at runtime, and to decide which adaptation actions may be used to improve overall performance in a composition instance. An optimizer component decides, whether applying these changes makes sense economically (i.e., whether the costs of violating the SLAs are bigger than the adaptation costs). If this is the case, the respective actions are applied in an automated way. At its core, PREvent is a self-optimizing system in the sense of autonomic computing, with the target of minimizing the total costs of adaptations and SLA violations for the service provider.
Shape by example (2001)

Article Share on Shape by example Authors: Peter-Pike J. Sloan Microsoft Research Microsoft ResearchView Profile , Charles F. Rose Microsoft Research Microsoft ResearchView Profile , Michael F. Cohen Microsoft Research Microsoft ResearchView Profile Authors Info & Claims I3D '01: Proceedings of the 2001 symposium on Interactive 3D graphicsMarch 2001 Pages 135–143https://doi.org/10.1145/364338.364382Online:01 March 2001Publication History 205citation1,387DownloadsMetricsTotal Citations205Total Downloads1,387Last 12 Months50Last 6 weeks4 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Abstraction Techniques in Modern Programming Languages (1984)

Modern Programming languages depend on abstraction: they manage complexity by emphazing what is significant to the user and suppressing what is not.
Diabetes-induced alteration in D-[2-3H] glucose detritiation by erythrocytes: intrinsic or environmental perturbation of phosphoglucoisomerase? (1990)

SCOPUS: ar.j
r Carotene Hydroxylase Gene from the Cyanobacterium Synechocystis sp. PCC6803 (1998)

The ORF sll1468 of Synechocystis sp. PCC6803 was identified as a gene for beta-carotene hydroxylase by functional complementation in a beta-carotene-producing Escherichia coli. The gene product of ORF sll1468 added hydroxyl groups to the beta-ionone rings of beta-carotene (beta, beta-carotene) to form zeaxanthin (beta, beta-carotene-3,3'-diol). This newly identified beta-carotene hydroxylase does not show overall amino acid sequence similarity to the known beta-carotene hydroxylases. However, it showed significant sequence similarity to beta-carotene ketolases of marine bacteria and a green alga.
Adhesive properties of heat-sealed EVAc/PE films in dependence on recipe, processing, and sealing parameters (2014)

The investigated peel system in this study consists of a polyolefine-based, coextruded, three-layer film having ethylene-vinyl acetate (EVAc) copolymer at the interface, heat sealed against a biaxial-oriented polyethylene terephthalate film. This system can primarily be found in the packaging industry offering a residue-free and non-destructive peel behavior. The peel force required to separate the joint depends on the mass fraction of vinyl acetate (VAc) in the EVAc copolymer, the processing conditions in the blowing process of the PE/PEVAc film, and on the sealing parameters. In dependence on the processing conditions and sealing parameters, the standard peel system with EVAc copolymer containing 18 wt.% VAc was investigated. The processing parameters were varied among the processing line of the blown film and their influence on the peel properties were studied. As processing parameters the screw speed within the extruder and the resulting layer thickness, the cooling behavior of the film bubble and the blow-up ratio (BUR) of the film bubble were investigated. The effect of pretreatment conditions was also investigated. The investigations revealed a significant dependence of the peel force on the pretreatment conditions. Processing conditions and the VAc content have a minor impact on the peel properties.
Белок FUS: физиологические функции и роль в развитии бокового амиотрофического склероза, "Молекулярная биология" (2017)

Certain forms of amyotrophic lateral sclerosis (ALS) are associated with an altered compartmentalization of FUS and its aggregation in the cytoplasm of motoneurons. FUS is a DNA/RNA-binding protein that is involved in DNA repair and the regulation of transcription, splicing, RNA transport, and local translation. Two theories have been proposed to explain the mechanism of the pathophysiological process in ALS. The theories attribute degeneration of motor neurons to either loss or gain of FUS function. The review describes the main physiological functions of FUS and considers evidence for each of the theories of ALS pathogenesis.
Educational bench: self-controlled synchronous machine (2008)

This article deals with the presentation of an experimental bench dedicated to the teaching of electromechanical systems during undergraduate curriculum. This bench permits to explain the main principles of an elementary synchronous motor by a practical approach of the physical phenomena. At first, students start to describe theoretically the motor based on the fundamental electromagnetic relations and concretise their calculations by a progressive realization of their coil windings and finally the electromechanical characterization of the motor. The educational approach is done in order to bring students to face with essential questions about machines and electrical drives.
Google Penguin: Evasion in Non-English Languages and a New Classifier (2013)

Web spam techniques aim to mislead search engines so that web spam pages get ranked higher than they deserve. This leads to misleading search results as spam pages might appear in search results although the content of these spam pages might not be related to the search terms. Despite the effort of search engines to deploy various techniques to detect and filter out web spam pages from being listed in their search results, spammers continue to develop new tactics to evade search engines detection mechanisms. In this paper, we study the effectiveness and accuracy of newly developed anti-spamming techniques in Google search engine. Focusing on Arabic spam pages, our study results show that Google anti-spamming techniques are ineffective against spam pages with Arabic content. We explore various types of web spam detection features to obtain an appropriate set of detection features that yield a reasonable detection accuracy. In order to build and evaluate our classifier, we collect and manually label a dataset of Arabic web pages, including both benign and spam pages. We believe this Arabic web spam corpus helps researchers in conducting sound measurement studies. We also develop a browser plug-in that utilizes our classifier and warns the user about web spam pages before accessing them, upon clicking on a search term. The plug-in has also the ability to filter out search engine results.
BET Proteins as Targets for Anticancer Treatment (2017)

Bromodomain and extraterminal domain (BET) proteins are epigenetic readers that regulate gene expression and are involved in cancer pathogenesis. Over the last years, several BET inhibitors have been developed and clinically tested. Results from the first clinical trials show limited single-agent activity in a small subset of patients with hematologic malignancies and in NUT carcinoma. Adverse events have been observed and may limit treatment compliance. Here, we review the preclinical rationale for targeting BET proteins in cancer and the preliminary results from clinical trials, and outline future directions for the use of BET inhibitors as antitumor agents.<b>Significance:</b> BET inhibitors represent a new class of anticancer agents. Results from the first clinical trials confirm the antitumor potential of BET inhibitors, but their efficacy as single agents seems to be limited. Based on preclinical data, combination therapies with other anticancer agents and the development of a new generation of compounds may open new possibilities for targeting BET proteins as effective anticancer strategies. <i>Cancer Discov; 8(1); 24-36. ©2017 AACR.</i>
Deformation analysis of tuffaceous sediments in the Volcanic Tableland near Bishop, California (2009)

Small-scale brittle faults and fractures that cut bedded tuffaceous sediments of variable textures and grain sizes were studied in a 110-m-long cutbank exposure of poorly consolidated sediments at the southern erosional boundary of the Volcanic Tableland, Owens Valley, California. This study was motivated by the need to evaluate potential length scales for lateral fl ow in nonwelded bedded tuffs and tuffaceous sediments at Yucca Mountain, Nevada-the site of a potential high-level radioactive waste repository. Small-displacement (<20 cm) faults and fractures are strongly clustered and spatially correlated with larger faults (displacements >20 cm). Vertical fractures are present throughout the exposure, but fracture frequency is generally highest in the vicinity of larger faults. Fault zones are characterized by grain-size reduction and discrete slip surfaces, the number of which increases with increasing displacement. A semiquantitative stress fi eld interpretation, based on tectonic constraints and reconstruction of overburden thicknesses, yields a simple history of burial, deformation, and exhumation under continuous tectonic extension. We interpret the deformation to include shear (faults), hybrid (faults, nonvertical fractures), and tensile (vertical fractures) failure of the tuffaceous sediments under conditions of low overburden stress (<2.5 MPa). The intersecting network of faults and fractures is characterized by grain comminution, cementation, and fracture dilation. These features, in conjunction with stratigraphic layering, likely produce anisotropic permeability, where maximum permeability is parallel to fault and fracture strike.
Optical Absorption in Commercial Single Mode Optical Fibers in a High Energy Physics Radiation Field (2008)

This paper reports on the radiation induced attenuation of light at 1310 nm and 1550 nm in 12 commercially available single mode (SM) optical fibers. The fiber samples are exposed to gamma rays from a <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">60</sup> Co source and to a high energy physics radiation field. The attenuation is studied as a function of total dose, dose rate, light power and temperature. Radiation hard fibers from one manufacturer show an extraordinary low attenuation for light at 1310 nm that does not exceed 5 dB/km even after a total dose of 1 MGy. 2500 km of this type of fiber have been produced by the manufacturer and quality assurance measurements of the production batches are presently ongoing.
Supplemental Figure Legends from Adenosine A<sub>2A</sub> Receptors Intrinsically Regulate CD8<sup>+</sup> T Cells in the Tumor Microenvironment (2023)

&lt;p&gt;Supplemental Figure legends&lt;/p&gt;
Comprehensive Analysis of the Acute Toxicities Induced by Systemic Administration of Cationic Lipid:Plasmid DNA Complexes in Mice (2000)

A major limitation associated with systemic administration of cationic lipid:plasmid DNA (pDNA) complexes is the vector toxicity at the doses necessary to produce therapeutically relevant levels of transgene expression. Systematic evaluation of these toxicities has revealed that mice injected intravenously with cationic lipid:pDNA complexes develop significant, dose-dependent hematologic and serologic changes typified by profound leukopenia, thrombocytopenia, and elevated levels of serum transaminases indicative of hepatocellular necrosis. Vector administration also induced a potent inflammatory response characterized by complement activation and the induction of the cytokines IFN-gamma, TNF-alpha, IL-6, and IL-12. These toxicities were found to be transient, resolving with different kinetics to pretreatment levels by 14 days posttreatment. The toxic syndrome observed was independent of the cationic lipid:pDNA ratio, the cationic lipid species, and the level of transgene expression attained. Mechanistic studies determined that neither the complement cascade nor TNF-alpha were key mediators in the development of these characteristic toxicities. Administration of equivalent doses of the individual vector components revealed that cationic liposomes or pDNA alone did not generate the toxic responses observed with cationic lipid:pDNA complexes. Only moderate leukopenia was associated with administration of cationic liposomes or pDNA alone, while only mild thrombocytopenia was noted in pDNA-treated animals. These results establish a panel of objective parameters that can be used to quantify the acute toxicities resulting from systemic administration of cationic lipid:pDNA complexes, which in turn provides a means to compare the therapeutic indices of these vectors.
X-ray powder diffraction study of Sn 0.59 Ti 0.41 Te 3 O 8 (2008)

The crystal structure of titanium-tin tellurium oxide Sn 0.59 Ti 0.41 Te 3 O 8 has been determined using X-ray powder diffraction techniques. At room temperature, the title compound crystallizes in cubic space group Ia -3, with lattice parameter a =11.05515(6) Å. Rietveld refinement of the structure led to final confidence factors R p =0.0395 and R wp =0.0577. The structure of Sn 0.59 Ti 0.41 Te 3 O 8 consists of isolated Ti/SnO 6 -octahedra slightly deformed in the a direction. The TeO 4 E [ E =lone pair of Te(IV) atoms] groups are located between the octahedra ensuring the stability of the structure by Ti/Sn-O-Te bonding contacts. Only one peak in thermal behavior was detected for this compound at 488 K by differential scanning calorimetry experiment. An IR spectroscopic study is employed as a means to obtain preliminary structural information and shows the presence of the Ti/SnO 6 and TeO 4 E groups. This result is later confirmed by X-ray diffraction studies.
Deoxynivalenol resistance as a component of FHB resistance (2017)

Fusarium head blight (FHB) is one of the most devastating diseases of wheat (Triticum aestivum), barley (Hordeum vulgare) and other small grain cereals grown in warm and humid regions worldwide. In addition to yield loss, the disease compromises the quality of infected grain as a result of contamination with a range of Fusarium mycotoxins that are harmful to human and animal health. Deoxynivalenol (DON) is the most prevalent trichothecene mycotoxin found in Fusarium-infected grains. DON acts as a virulence factor for Fusarium, facilitating disease spread within wheat heads. Resistance to DON is an innate component of FHB resistance. Here we review FHB as a globally important disease, with a specific focus on the role of DON in disease development, the importance of its’ resistance in plant defence against Fusarium and the current knowledge regarding the genes activated as part of the cereal defence against the toxin.