gebhart/patrepeval huggingface dataset:
Enhanced Privacy ID: A Direct Anonymous Attestation Scheme with Enhanced Revocation Capabilities. (2007)

Direct Anonymous Attestation (DAA) is a scheme that enables the remote authentication of a Trusted Platform Module (TPM) while preserving the user’s privacy. A TPM can prove to a remote party that it is a valid TPM without revealing its identity and without linkability. In the DAA scheme, a TPM can be revoked only if the DAA private key in the hardware has been extracted and published widely so that verifiers obtain the corrupted private key. If the unlinkability requirement is relaxed, a TPM suspected of being compromised can be revoked even if the private key is not known. However, with the full unlinkability requirement intact, if a TPM has been compromised but its private key has not been distributed to verifiers, the TPM cannot be revoked. Furthermore, a TPM cannot be revoked from the issuer, if the TPM is found to be compromised after the DAA issuing has occurred. In this paper, we present a new DAA scheme called Enhanced Privacy ID (EPID) scheme that addresses the above limitations. While still providing unlinkability, our scheme provides a method to revoke a TPM even if the TPM private key is unknown. This expanded revocation property makes the scheme useful for other applications such as for driver’s license. Our EPID scheme is efficient and provably secure in the same security model as DAA, i.e. in the random oracle model under the strong RSA assumption and the decisional Diffie-Hellman assumption.
Molecular Vectors for Gene Delivery to Cancer Cells (2004)

Cancer gene therapy relies on nucleic acid carriers. Because of their diversity, viruses fulfill most requirements for gene delivery in clinical situations. However, parallel evolution of viruses and their hosts has made foreign protein particles, as well as infected cells, effective targets for the immune system. Although the latter consequence can be turned into therapeutic benefit, the former excludes repetitive treatment, which is the only reasonable approach for a chronic disease such as cancer.
Car-following characteristics of various vehicle types in respective driving phases (2020)

The dynamics of mixed traffic were analysed by examining the driving features of various vehicles based on their car-following behaviours in a test-driving circuit. By applying decision tree analysis to the observed data, we successfully compared the acceleration, velocity difference and distance gap of different vehicles during driving trials and quantitatively extracted the features of these physical values from the respective driving phases. Our investigation resulted in a short-distance gap for motorcycles in the steady phase, while a difference in the distance gap between cars and trucks appeared in the early deceleration phase. We also obtained the characteristic behaviours of these vehicle types in different driving phases. Our findings indicate that the car-following characteristics of various types of vehicles are affected by the recognition of vehicle agility. Furthermore, we propose the necessary model parameters for replicating these features in different driving phases.
Lower Dimensional Interpolation in Overlapping Composite Mesh Difference Methods (1999)

We propose a modified Composite Mesh Difference Method (CMDM) in which a lower dimensional interpolation can be used along the interface of the nonmatching grids. The advantage of this approach is that fewer interpolation points are needed while the
Integrated Weed Management Systems Technology for Pest Management (1982)

The people of the world required from the dawn of time until 1830 to reach a population of 1 billion. By 1960, we reached 3 billion and by 1980 we had a population of about 4 billion. It is estimated that by the year 2000 there will be 7 billion people in the world. Just 30 yr from now the world's population will have doubled. This means that within the next 30 yr we must produce as much food as we have produced since the beginning of history. Can we feed this many people? Yes, but expanded research to develop improved technology will be required to meet the challenge.
Epicardial YAP/TAZ orchestrate an immunosuppressive response following myocardial infarction (2017)

Ischemic heart disease resulting from myocardial infarction (MI) is the most prevalent form of heart disease in the United States. Post-MI cardiac remodeling is a multifaceted process that includes activation of fibroblasts and a complex immune response. T-regulatory cells (Tregs), a subset of CD4+ T cells, have been shown to suppress the innate and adaptive immune response and limit deleterious remodeling following myocardial injury. However, the mechanisms by which injured myocardium recruits suppressive immune cells remain largely unknown. Here, we have shown a role for Hippo signaling in the epicardium in suppressing the post-infarct inflammatory response through recruitment of Tregs. Mice deficient in epicardial YAP and TAZ, two core Hippo pathway effectors, developed profound post-MI pericardial inflammation and myocardial fibrosis, resulting in cardiomyopathy and death. Mutant mice exhibited fewer suppressive Tregs in the injured myocardium and decreased expression of the gene encoding IFN-γ, a known Treg inducer. Furthermore, controlled local delivery of IFN-γ following MI rescued Treg infiltration into the injured myocardium of YAP/TAZ mutants and decreased fibrosis. Collectively, these results suggest that epicardial Hippo signaling plays a key role in adaptive immune regulation during the post-MI recovery phase.
Mesenteric Organ Production, Hepatic Metabolism, and Renal Elimination of Norepinephrine and Its Metabolites in Humans (1996)

This study used regional differences in plasma concentrations of norepinephrine and its metabolites to examine how production of the transmitter by sympathetic nerves, in particular, those innervating mesenteric organs, is integrated with metabolism by the liver and elimination by the kidneys. Higher concentrations of norepinephrine, its glycol metabolites 3,4-dihydroxyphenylglycol and 3-methoxy-4-hydroxyphenylglycol and their sulfate conjugates in portal venous than arterial plasma indicate substantial production of norepinephrine by mesenteric organs (15.5 nmol/min). Much lower concentrations of norepinephrine and its glycol metabolites in plasma leaving than entering the liver indicate their efficient hepatic removal (20 nmol/min). Higher concentrations of vanillylmandelic acid in the hepatic outflow than inflow indicate that this metabolic end product is produced largely from the norepinephrine and glycol metabolites removed by the liver. Renal elimination of vanillylmandelic acid (18-20 nmol/min), produced mainly by the liver (17 nmol/min), and of 3-methoxy-4-hydroxyphenylglycol sulfate (7-9 nmol/min), produced largely by mesenteric organs (7 nmol/min), compromised 86-91% of the total renal elimination of norepinephrine metabolites. The results show that mesenteric organs produce about one-half of the norepinephrine formed in the body. The liver removes substantial amounts of circulating norepinephrine and its glycol metabolites and converts these compounds to vanillylmandelic acid, which is then eliminated from the body by the kidneys. The sulfate conjugates are also metabolic end products eliminated by the kidneys. However, these metabolites are produced by extrahepatic tissues, in particular, mesenteric organs, which represent a significant source of sulfate-conjugated norepinephrine and 3,4-dihydroxyphenylglycol, and the main source of sulfate-conjugated 3-methoxy-4-hydroxyphenylglycol.
Privacy Preserving K-means Clustering with Chaotic Distortion (2007)

Randomized data distortion is a popular method used to mask the data for preserving the privacy. But the appropriateness of this method was questioned because of its possibility of disclosing original data. In this paper, the chaos system, with its unique characteristics of sensitivity on initial condition and unpredictability, is advocated to distort the original data with sensitive information for privacy preserving k-means clustering. The chaotic distortion procedure is proposed and three performance metrics specifically for k-means clustering are developed. We use a large scale experiment (with 4 real world data sets and corresponding reproduced 40 data sets) to evaluate its performance. Our study shows that the proposed approach is effective; it not only can protect individual privacy but also maintain original information of cluster center
Pd-Catalyzed C4-Olefination of Oxazoles via C–H Bond Activation: Divergent Synthesis of Functionalized Amino Alcohol and Amino Acid Derivatives (2011)

A Pd-catalyzed C4-olefination of oxazoles via C-H bond activation under mild conditions was achieved. The reaction was shown to be general over a range of substrates. New protocols for the divergent transformation of these products to provide functionalized amino alcohol and amino acid derivatives have also been established.
Balancing transport and physical Layers in wireless multihop networks: jointly optimal congestion control and power control (2005)

In a wireless network with multihop transmissions and interference-limited link rates, can we balance power control in the physical layer and congestion control in the transport layer to enhance the overall network performance while maintaining the architectural modularity between the layers? We answer this question by presenting a distributed power control algorithm that couples with existing transmission control protocols (TCPs) to increase end-to-end throughput and energy efficiency of the network. Under the rigorous framework of nonlinearly constrained utility maximization, we prove the convergence of this coupled algorithm to the global optimum of joint power control and congestion control, for both synchronized and asynchronous implementations. The rate of convergence is geometric and a desirable modularity between the transport and physical layers is maintained. In particular, when congestion control uses TCP Vegas, a simple utilization in the physical layer of the queueing delay information suffices to achieve the joint optimum. Analytic results and simulations illustrate other desirable properties of the proposed algorithm, including robustness to channel outage and to path loss estimation errors, and flexibility in trading off performance optimality for implementation simplicity. This work presents a step toward a systematic understanding of as decomposition, where the overall communication network is modeled by a generalized network utility maximization problem, each layer corresponds to a decomposed subproblem, and the interfaces among layers are quantified as the optimization variables coordinating the subproblems. In the case of the transport and physical layers, link congestion prices turn out to be the optimal layering prices..
Relations of Circulating Resistin and Adiponectin and Cardiac Structure and Function: The Framingham Offspring Study (2011)

Obesity is associated with pathological cardiac remodeling and risk of heart failure (HF). Adipocytokines (ADKs) may mediate the increased risk of cardiovascular disease associated with excess adiposity. Yet data relating ADKs to cardiac remodeling phenotypes are sparse. We related two circulating ADKs, resistin and adiponectin, to three important echocardiographic markers of cardiac remodeling, left ventricular mass (LVM), left atrial diameter (LAD), and LV fractional shortening (LVFS) in 2,615 participants (mean age 61 years, 55% women) in the Framingham Offspring Study. Adiponectin concentrations were inversely related to LVM in multivariable linear regression models adjusting for key clinical correlates including BMI (regression coefficient per s.d.-increment in ln-adiponectin = -3.37, P = 0.02; P for trend across quartiles = 0.02). Adiponectin was not associated with LAD or LVFS (P > 0.56). Resistin concentrations were inversely related to LVFS (regression coefficient per s.d.-increment in ln-resistin = -0.01, P = 0.03; P for trend across quartiles = 0.04). Resistin was not associated with LVM or LAD (P > 0.05). In our moderate-sized, community-based sample, higher circulating concentrations of adiponectin and resistin were associated with lower LVM and lower LVFS, respectively. In conclusion, these associations identify potential mechanisms by which excess adiposity may mediate adverse cardiac remodeling and HF risk.
Computer-Generated Volume Holograms in the THz (2010)

Recent advances in rapid prototyping provide the promise of direct, rapid fabrication of volumetric optical components in the terahertz. We are investigating use of this new technology for fabrication of a Bragg-selective computer-generated volume hologram.
Study on the models of cross-chain inventory collaboration in the cluster supply chain (2008)

Considering the cross-chain inventory collaboration in the cluster supply chain, this paper discussed and comparatively analyzed two models: the one is cross-chain inventory complementarily between enterprises of same tier and the other one is cross-chain inventory complementarily between enterprises of different tiers with the methods of system dynamics simulation. By the analysis of the simulation data, the paper found that using inventory complementarily between enterprises of different tiers can lead to a higher satisfaction rate of customer demand without big changes of inventory and can maintain this large satisfaction rate stably. Therefore, from the perspective of the inventory and customer satisfaction rate, the complementarily model between enterprises of different tiers is superior to the model between enterprises of same tier.
Substitution effect of sea tangle (ST) (Laminaria japonica) with tunic of sea squirt (SS) (Halocynthia roretzi) in diet on growth and carcass composition of juvenile abalone (Haliotis discus, Reeve 1846) (2017)

Substitution effect of sea tangle (ST) with tunic of sea squirt (SS) in diet on growth and carcass composition of juvenile abalone was determined. One thousand four hundred and seventy abalones were distributed into 21 containers. Six formulated diets in triplicate were prepared. A 200 g/kg ST was included into the ST0 diet. The 200, 400, 600, 800 and 1000 g/kg of ST were substituted with the same amount of tunic of SS, referred to as the ST200, ST400, ST600, ST800 and ST1000 diets, respectively. Finally, Undaria was prepared to compare effect of the formulated diets on performance of abalone. The experimental diets were fed to abalone for 16 weeks. Weight gain of abalone fed the ST400 diet was higher than that of abalone fed the ST0, ST600, ST800 and ST1000 diets and Undaria. Weight gain of abalone fed the formulated diets was higher than that of abalone fed the Undaria. The chemical composition of the carcass of abalone was affected by dietary substitution of ST with tunic of SS. In conclusion, ST could be completely substituted with tunic of SS without retardation in performance of abalone. Abalone fed the ST400 diet substituting 400 g/kg ST with tunic of SS achieved the best growth.
Evidence that the Mediobasal Hypothalamus is Involved in Serotonergic Stimulation of Renin Secretion (1982)

The effect of the serotonin-releasing drug parachloroamphetamine (PCA) on plasma renin activity was studied in rats 4 days after surgical lesions of the mediobasal hypothalamus, anterolateral deafferentation of the mediobasal hypothalamus, posterolateral deafferentation, or hypophysectomy. PCA increased plasma renin activity in sham-operated rats, but it failed to increase plasma renin activity in rats with mediobasal hypothalamic lesions or posterolateral deafferentation. The response to PCA was unaffected by anterolateral deafferentation and enhanced by hypophysectomy. There were no significant differences in plasma renin activity in lesioned, deafferented, and hypophysectomized rats injected with saline. The data indicate that the mediobasal hypothalamus is part of the pathway by which central serotonergic neurons affect renin secretion, and that the effect is not mediated via hormones of the pituitary gland.
Simulating the TravTek Route Guidance Logic Using the Integration Traffic Model (1991)

&lt;div class="htmlview paragraph"&gt;The first phase of the TravTek IVHS experiment will involve the use of in-vehicle Route Guidance Systems (RGS) to determine the best routes through the Greater Orlando Area. These routes will be computed in a distributive fashion based on minute-to-minute travel time updates that are provided by a central Traffic Management Center (TMC). This paper describes the most important traffic engineering aspects of the data fusion, dissemination, and in-vehicle processing of the TravTek system with the intent of demonstrating how the features of each of these steps can be modelled within the TravTek version of the INTEGRATION traffic simulation model.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;The simulation of these system features is initially intended to assist in developing appropriate TMC and in-vehicle unit system control settings, and to determine the sensitivity of the benefit estimates to alternate parameter settings or system configurations. The INTEGRATION simulation model will subsequently also be utilized to simulate and explore any level of market penetration traffic effects, as well as the transferability of the TravTek results to other networks and/or different demand patterns.&lt;/div&gt;
Glioblastoma Multiforme after Radiotherapy for Acromegaly (1983)

A case of glioblastoma multiforme that occurred 14 years after radiotherapy for acromegaly is presented. The striking correspondence between the anatomy of the tumor and the geometry of the radiation ports is suggestive of a causal relationship. Previously reported cases of radiation-associated glioma are reviewed, and a brief appraisal of the evidence for induction of these lesions by radiation is presented. The differentiation of radiation-associated neoplasms from radionecrosis is also discussed.
Identification et étude d'un nouveau mécanisme nucléaire de régulation post-transcriptionnelle par les micro-ARN (2016)

Les miARN sont de petits ARN non codant dont la taille varie entre 21-24 nucleotides. Ils jouent un role de regulateurs post-transcriptionnels en utilisant leur complementarite de sequence avec l’ARN messager (ARNm) cible afin d’induire sa repression. Grâce a la proteine Argonaute 2 (Ago2) dans laquelle les miARN sont incorpores formant ainsi le complexe miRISC, des cofacteurs sont recrutes afin d’induire la degradation ou le blocage de la traduction de l’ARNm cible. Initialement connus pour reguler leurs cibles dans le cytoplasme, les miARN sont de plus en plus decrits comme etant des regulateurs de l’expression genique au niveau nucleaire. Dans ce travail, nous avons demontre la presence, au sein du noyau, d’un nouveau mecanisme de regulation post-transcriptionel par les miARN dont les facteurs majeurs sont Sfpq et Pspc1
The Use of the Fugo Blade in Corneal Surgery (2006)

Although the Fugo Blade is currently approved by the Food and Drug Administration for anterior capsulotomy, our study demonstrates that the Fugo Blade can safely and quickly produce resistance-free cuts in corneal tissue in animals, opening additional avenues for use of this device in corneal surgery.
Use of electronic health records to support a public health response to the COVID-19 pandemic in the United States: a perspective from 15 academic medical centers (2020)

Our goal is to summarize the collective experience of 15 organizations in dealing with uncoordinated efforts that result in unnecessary delays in understanding, predicting, preparing for, containing, and mitigating the COVID-19 pandemic in the US. Response efforts involve the collection and analysis of data corresponding to healthcare organizations, public health departments, socioeconomic indicators, as well as additional signals collected directly from individuals and communities. We focused on electronic health record (EHR) data, since EHRs can be leveraged and scaled to improve clinical care, research, and to inform public health decision-making. We outline the current challenges in the data ecosystem and the technology infrastructure that are relevant to COVID-19, as witnessed in our 15 institutions. The infrastructure includes registries and clinical data networks to support population-level analyses. We propose a specific set of strategic next steps to increase interoperability, overall organization, and efficiencies.
Contract-Theoretic Resource Allocation for Critical Infrastructure Protection (2015)

Critical infrastructure protection (CIP) is envisioned to be one of the most challenging security problems in the coming decade. One key challenge in CIP is the ability to allocate resources, either personnel or cyber, to critical infrastructures with different vulnerability and criticality levels. In this work, a contract- theoretic approach is proposed to solve the problem of resource allocation in critical infrastructure with asymmetric information. A control center (CC) is used to design contracts and offer them to infrastructures' owners. A contract can be seen as an agreement between the CC and infrastructures using which the CC allocates resources and gets rewards in return. Contracts are designed in a way to maximize the CC's benefit and motivate each infrastructure to accept a contract and obtain proper resources for its protection. Infrastructures are defined by both vulnerability levels and criticality levels which are unknown to the CC. Therefore, each infrastructure can claim that it is the most vulnerable or critical to gain more resources. A novel mechanism is developed to handle such an asymmetric information while providing the optimal contract that motivates each infrastructure to reveal its actual type. The necessary and sufficient conditions for such resource allocation contracts under asymmetric information are derived. Simulation results show that the proposed contract-theoretic approach maximizes the CC's utility while ensuring that no infrastructure has an incentive to ask for another contract, despite the lack of exact information at the CC.
Simulink Modeling and Dynamic Study of Fixed-Speed, Variable-Speed, and Ternary Pumped Storage Hydropower (2022)

Pumped Storage Hydropower (PSH) is one of the most popular energy storage technologies in the world. It uses an upper reservoir to store water which can be later used during high-demand. In the United States, most of the energy storage capability actually corresponds to PSH. Moreover, PSH also brings multiple benefits to grid operation. This report presents the Simulink models of three common PSH technologies: Fixed-Speed (FS), Variable-Speed (VS), and Ternary (T)-PSH. These models are available to the general public on this GitHub repository 1 , which contains the MATLAB model initialization files, the Simulink model files, and supplementary MATLAB code used to obtain the figures in this work. For each PSH model, an introductory description of the model components and other relevant functionalities are provided. For further information regarding the models and the initialization parameters, the reader is referred to the shared files in the repository. This report also presents the dynamic behavior of each model. The response of such models to a load event is analyzed and matched with each model?s features. A custom IEEE 39 bus case is employed for the FS and T-PSH simulations, while the VS-PSH is simulated on a simplified three-bus test system due to the computational complexity of the model. For the T-PSH, the steady-state and the switching between several operating modes are also studied in this work. * Send correspondence to mjimene@sandia.gov . 1 See: https://github.com/sandialabs/Simulink_PumpedStorageHydropower .