gebhart/patrepeval huggingface dataset:
Dynamic Modeling and Simulation of Flexible Robots With Prismatic Joints (1990)

A dynamic model for flexible manipulators with prismatic joints is presented in Part I of this study. Floating frames following a nominal rigid body motion are introduced to describe the kinematics of the flexible links. A Lagrangian approach is used in deriving the equations of motion. The work done by the rigid body axial force through the axial shortening of the link due to transverse deformations is included in the Lagrangian function. Kinematic constraint equations are used to describe the compatibility conditions associated with revolute joints and prismatic joints, and incorporated into the equations of motion by Lagrange multipliers. The small displacements due to the flexibility of the links are then discretized by a displacement based finite element method. Equations of motion are derived for the cases of prescribed rigid body motion as well as prescribed joint torques/forces through application of Lagrange’s equations. The equations of motion and the constraint equations result in a set of differential algebraic equations. A numerical procedure combining a constraint stabilization method and a Newmark direct integration scheme is then applied to obtain the system response. An example, previously treated in the literature, is presented to validate the modeling and solution methods used in this study.
User assisted stereo image retargetting (2013)

The wide availability of stereoscopic 3D TVs and mobile displays created a considerable market for content producers. This opened a new phase for researchers to study on methods to alter and process the content for various purposes. This study concentrates on user assisted disparity remapping for stereo image footage. The disparity of an object of interest is altered while leaving the remaining scene unattended. This application is useful in the sense that it provides a method for emphasizing/de-emphasizing an object on the scene by adjusting its depth with respect to the camera. The proposed technique can also be used as a post processing step for retargeting stereoscopic footage on different display sizes and resolutions. The proposed technique involves an MRF based energy minimization step for interactive stereo image segmentation, where user assistance on just one of the stereo pairs is required for determining the location of stereo object pair. Qualitative and quantitative evaluation of the generated segments and the disparity adjusted images prove the functionality and superiority of the proposed technique.
Organic Field‐Effect Transistors based on Highly Ordered Single Polymer Fibers (2011)

Ultrahigh-mobility organic field-effect transistors (OFETs) based on a CDT-BTZ donor-acceptor copolymer are realized by reaching high molecular order and pronounced alignment in single fibers within a short OFET channel via solution processing. The macromolecules directionally self-assemble in a quasi crystal-like order in the fibers providing in this way an unhindered charge carrier pathway with mobilities as high as 5.5 cm(2) V(-1) s(-1).
Tip potential of open-tip glass microelectrodes: theoretical and experimental studies (1983)

A mathematical analysis of the tip potential based on the main physicochemical phenomena occurring at the tip of a glass microelectrode is presented. The factors considered in the theoretical analysis are the diffusion of ions through the open tip, the conduction in the bulk solutions, the longitudinal conduction in the double layers at the glass-electrolyte interfaces, and to some extent, in a hydrated glass layer. A graphical analysis of the mathematical expressions as a function of the resistivity of test solutions is done and the distribution of the source potentials giving rise to the tip potential is studied. The experimental results presented in the paper confirm the validity of the proposed theoretical model. Comments for an improved use of glass microelectrodes in electrophysiological experiments are given throughout the paper.
Monolithically Integrated RF MEMS-Based Variable Attenuator for Millimeter-Wave Applications (2019)

This paper reports a millimeter-wave radio frequency (RF) microelectromechanical systems (MEMS)-based variable attenuator implemented by monolithically integrating CPW-based hybrid couplers with lateral MEMS varactors on a silicon-on-insulator (SOI) substrate. The MEMS varactor features a Chevron-type electrothermal actuator that controls the lateral movement of a thick plate allowing precise change of capacitive loading on a CPW line leading to a change in isolation between input and output. The proposed variable attenuator is successfully fabricated on an SOI substrate with a device footprint of 3.8 mm × 3.1 mm. The fabrication process provides flexibility to extend this module and implement more complex RF signal conditioning functions, thus making it more appealing to realize a wide range of reconfigurable RF devices. The measured RF performance shows that the device exhibits attenuation levels (S21) ranging from 10 to 25 dB, at the center frequency of 60 GHz with a bandwidth of 4 GHz and a return loss of better than 20 dB. The device involves laterally moving 20-μm-thick structures, hence offers reliable operation and eliminates MEMS problems like stiction, dielectric charging, and microwelding observed in surface micromachined thin membranes.
Project finance for alternative energy (1993)

This paper is intended to provide general advice to sponsors of renewable energy projects who expect to raise project-based financing from commercial banks to fund the development of their projects. It sets out, for the benefit of such sponsors, how bankers typically approach the analysis of these undertakings and in particular the risk areas on which they concentrate. By doing so it should assist sponsors to maximise their prospects of raising bank finance.
22.9 A 12nm 18.1TFLOPs/W Sparse Transformer Processor with Entropy-Based Early Exit, Mixed-Precision Predication and Fine-Grained Power Management (2023)

Large language models have substantially advanced nuance and context understanding in natural language processing (NLP), further fueling the growth of intelligent conversational interfaces and virtual assistants. However, their hefty computational and memory demands make them potentially expensive to deploy on cloudless edge platforms with strict latency and energy requirements. For example, an inference pass using the state-of-the-art BERT-base model must serially traverse through 12 computationally intensive transformer layers, each layer containing 12 parallel attention heads whose outputs concatenate to drive a large feed-forward network [1]. To reduce computation latency, several algorithmic optimizations have been proposed, e.g., a recent algorithm dynamically matches linguistic complexity with model sizes via entropy-based early exit [2]. Deploying such transformer models on edge platforms requires careful co-design and optimizations from algorithms to circuits, where energy consumption is a key design consideration.
Hydrodynamics of a lamella electrosettler (1989)

Abstract Using the principles of conservation of mass and momenturn for each phase, a theory is developed for describing quantitatively the sedimentation of colloidal particles in vessels having electrodes that are inclined to the vertical. As a limiting case, a kinematic settling formula was derived that describes the motion of settling fronts of colloidal alumina particles suspended in tetralin as a function of angle of inclination and strength of applied electric field in terms of electrophoretic mobilities. A hydrodynamic computer model shows the flow patterns and settling behavior of such lamella settlers with and without an applied electric field. The predicted motions of the settling fronts and the thicknesses of the clear boundary layers above the upper wall of the inclined vessels globally agreed with the experimental observations.
<title>Broadband Bragg-Lippmann volume holographic mirrors</title> (1995)

In this paper, the optical properties of broadband Lippmann-Bragg volume holographic mirrors are analyzed. These mirrors have a wavelength bandwidth much higher than their Bragg bandwidth, which is a result of Kogelnik's theory. While Kogelnik's model assumes uniform distribution of the distance between Bragg planes as a function of the vertical coordinate, the experimental results presented in this paper strongly demonstrate that Kogelnik's theory is not valid in the case of broadband Lippmann-Bragg volume holographic mirrors.
Probabilistic Model Checking Modulo Theories (2007)

Probabilistic models are widely used to analyze embedded, networked, and more recently biological systems. Existing numerical analysis techniques are limited to finite- state models and suffer from the state explosion problem. As a consequence, the user often has to manually abstract the intended model to get a tractable one. To this end, we propose the predicate abstraction model checker PASS which automates this process. We leverage recent advances in automatic theorem proving to compute tractable finite-state models. Experiments show the feasibility of our approach. To the best of our knowledge, this is the first time that properties of probabilistic infinite-state models have been verified at this level of automation.
Symmetries, Chirp-Free Points and Bistability in Dispersion Msnaged Fibre Lines (1999)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text S. K. Turitsyn, J. H. B. Nijhof, V. K. Mezentsev, and N. J. Doran, "Symmetries, Chirp-Free Points and Bistability in Dispersion Msnaged Fibre Lines," in Nonlinear Guided Waves and Their Applications, OSA Technical Digest (Optica Publishing Group, 1999), paper ThD14. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Introduction to Formula SAE® Suspension and Frame Design (1997)

&lt;div class="htmlview paragraph"&gt;This paper is an introduction to Formula SAE&lt;sup&gt;®&lt;/sup&gt; (FSAE) suspension and frame design based on the experience of the design team at UM-Rolla. The basic theories and methodologies for designing these systems are presented so that new teams will have a baseline for their first FSAE design. Examples will be given based on UM-Rolla's 1996 FSAE entry.&lt;/div&gt;
Human Interferon (1981)

Interferon, originally discovered in England in 1957, has only recently become available in quantities which allowed the first clinical and scientific evaluations. Work in the author's laboratories is described, dealing with the sources of Interferon, its assay and production, its molecular properties, purification, chemical structure and the results of producing interferon from genetic engineering in other research institutes. The chemical synthesis of the interferon molecule is actively pursued as it shows such broad antiviral activity.
Biological Factors Influencing the RBE of Neutrons: Implications for Their Past, Present and Future Use in Radiotherapy (2001)

The recent resurgence of interest in fast-neutron therapy, particularly for the treatment of prostate cancer, warrants a review of the original radiobiological basis for this modality and the evolution of these concepts that resulted from subsequent experimentation with the fast-neutron beams used for randomized clinical trials. It is clear from current radiobiological knowledge that some of the postulates that formed the mechanistic basis for past clinical trials were incorrect. Such discrepancies, along with the inherent physical disadvantages of neutron beams in terms of collimation and intensity modulation, may partially account for the lack of therapeutic benefit observed in many randomized clinical trials. Moreover, it is equally apparent that indiscriminate prescription of fast-neutron therapy is likely to lead to an adverse clinical outcome in a proportion of patients. Hence any renewed efforts to establish a niche for this modality in clinical radiation oncology will necessitate the development of a triage system that can discriminate those patients who might benefit from fast-neutron therapy from those who might be harmed by it. In the future, fast-neutron therapy might be prescribed based upon the relative status of appropriate molecular parameters that have a differential impact upon radiosensitivity to photons compared to fast neutrons.
ChemInform Abstract: An Asymmetric Synthesis of 1,2,4‐Trioxane Anticancer Agents via Desymmetrization of Peroxyquinols Through a Broensted Acid Catalysis Cascade. (2013)

Abstract Trioxanes (IIIb), (IIIi), and (IV) show promising activity toward bone and lung cell cancer lines.
Test generation for clock-domain crossing faults in integrated circuits (2012)

Clock-domain crossing (CDC) faults are a serious concern for high-speed, multi-core integrated circuits. Even when robust design methods based on synchronizers and design verification techniques are used, process variations can introduce subtle timing problems that affect data transfer across clock-domain boundaries for fabricated chips. We present a test generation technique that leverages commercial ATPG tools, but introduces additional constraints, to detect CDC faults. We also present HSpice simulation data using a 45 nm technology to quantify the occurrence of CDC faults at clock-domain boundaries. Results are presented for synthesized IWLS05 benchmarks that include multiple clock domains. The results highlight the ineffectiveness of commercial transition-delay fault ATPG and the “coverage gap” resulting from the use of ATPG methods employed in industry today. While the proposed method can detect nearly all CDC faults, TDF ATPG is found to be severely deficient for screening CDC faults.
Production, properties, and thrombin inhibitory mechanism of hirudin amino-terminal core fragments. (1990)

Hirudin, a thrombin-specific inhibitor, comprises a compact amino-terminal core domain (residues 1-52) and a disordered acidic carboxyl-terminal tail (residues 53-65). An array of core fragments were prepared from intact recombinant hirudin by deletion of various lengths of its carboxyl-terminal tail on selective enzymatic cleavage. Hir1-56 and Hir1-53 were produced by pepsin digestion at Phe56-Glu57 and Asp53-Gly54. Hir1-52 was generated by Asp-N cleavage at Asn52-Asp53. Hir1-49 was prepared by cleavage of Gln49-Ser50 by chymotrypsin, elastase, and thermolysin. In addition, Hir1-62 (containing part of the carboxyl-terminal tail) was derived from Hir1-65 by selective removal of the three carboxyl-terminal amino acids using carboxypeptidase A. Hirudin amino-terminal core fragments were stable at extreme pH (1.47 and 12.6), high temperature (95 degrees C), and resistant to attack by various proteinases. For instance, following 24-h incubation with an equal weight of pepsin, the covalent structure of Hir1-52 remained intact and its anticoagulant activity unaffected. Unlike intact hirudin (Hir1-65) the inhibitory potency of which is a consequence of concerted binding of its amino-terminal and carboxyl-terminal domains to the active site and the fibrinogen recognition site of thrombin, the core fragments block only the active site of thrombin with binding constants of 19 nM (Hir1-56), 35 nM (Hir1-52), and 72 nM (Hir1-49). As an anticoagulant Hir1-56 is about 2-, 4-, and 30-fold more potent (on a molar basis) than Hir1-52, Hir1-49, and Hir1-43, respectively. Hir1-56 was also about 15-fold more effective than the most potent carboxyl-terminal fragment of hirudin, sulfated-Hir54-65, although they bind to independent sites on thrombin. The potential advantages of hirudin core fragments as antithrombotic agents are discussed in this report.
CGCDB: A web‐based resource for the investigation of gene coexpression in CHO cell culture (2011)

Abstract Coexpression analysis is a powerful, widely used methodology for the investigation of underlying patterns in gene expression data. This “guilt‐by‐association” approach aims to find groups of genes with closely correlated expression profiles. Observation of consistent correlations across phenotypically diverse samples indicates that these genes have a shared function. We have recently described the application of weighted gene coexpression network analysis (WGCNA) to a 295 sample production CHO cell line microarray dataset and elucidated groups of genes related to growth rate and cell‐specific productivity (Qp). In this study, we present the CHO gene coexpression database (CGCDB), a web‐based system, designed specifically for researchers in the CHO community to provide user‐friendly access to these gene–gene coexpression patterns. In addition to correlation between genes, the direct correlations between probesets and either growth rate or Qp are provided. Results are presented to the user via an interactive network diagram and in a downloadable tabular format. It is hoped that this resource will allow researchers to prioritize cell line engineering and/or biomarker candidates to enhance CHO‐based cell culture for the production of biotherapeutics. Availability: www.cgcdb.org . Biotechnol. Bioeng. 2012; 109:1368–1370. © 2011 Wiley Periodicals, Inc.
A type III ACC synthase, ACS7, is involved in root gravitropism in Arabidopsis thaliana (2013)

Ethylene is an important plant hormone that regulates developmental processes in plants. The ethylene biosynthesis pathway is a highly regulated process at both the transcriptional and post-translational level. The transcriptional regulation of these ethylene biosynthesis genes is well known. However, post-translational modifications of the key ethylene biosynthesis enzyme 1-aminocyclopropane-1-carboxylate (ACC) synthase (ACS) are little understood. In vitro kinase assays were conducted on the type III ACS, AtACS7, fusion protein and peptides to determine whether the AtACS7 protein can be phosphorylated by calcium-dependent protein kinase (CDPK). AtACS7 was phosphorylated at Ser216, Thr296, and Ser299 by AtCDPK16 in vitro. To investigate further the function of the ACS7 gene in Arabidopsis, an acs7-1 loss-of-function mutant was isolated. The acs7-1 mutant exhibited less sensitivity to the inhibition of root gravitropism by treatment with the calcium chelator ethylene glycol tetraacetic acid (EGTA). Seedlings were treated with gradient concentrations of ACC. The results showed that a certain concentration of ethylene enhanced the gravity response. Moreover, the acs7-1 mutant was less sensitive to inhibition of the gravity response by treatment with the auxin polar transport inhibitor 1-naphthylphthalamic acid, but exogenous ACC application recovered root gravitropism. Altogether, the results indicate that AtACS7 is involved in root gravitropism in a calcium-dependent manner in Arabidopsis.
Argonaute Autoantibodies as Biomarkers in Autoimmune Neurologic Diseases (2021)

This study provides Class III evidence that AGO-Abs are more frequent in patients with autoimmune neurologic diseases than controls.
A radiographic analysis of degenerative spondylolisthesis at the L4–5 level (2011)

The wide range in all radiographic parameters for LDS confirms the heterogeneous nature of this condition and suggests that a grading system to subclassify LDS may be clinically useful. On flexion and extension radiographs, increased translational motion correlated with increased angular motion. Anterior osteophyte size was not found to be predictive of segmental stability. This data set should prove beneficial to those seeking to subcategorize LDS in the future.
CA3 NMDA receptors are required for experience‐dependent shifts in hippocampal activity (2007)

The anatomical distribution of sensory-evoked activity recorded from the hippocampal long-axis can shift depending on prior experience. In accordance with Marr's computational model of hippocampal function, CA3 NMDA receptors have been hypothesized to mediate this experience-dependent shift in hippocampal activity. Here we tested this hypothesis by investigating genetically-modified mice in which CA3 NMDA receptors are selectively knocked-out (CA3-NR1 KO). First, we were required to develop an fMRI protocol that can record sensory-evoked activity from the mouse hippocampal long-axis. This goal was achieved in part by using a dedicated mouse scanner to image odor-evoked activity, and by using non-EPI (echo planer imaging) pulse sequences. As in humans, odors were found to evoke a ventral-predominant activation pattern in the mouse hippocampus. More importantly, odor-evoked activity shifted in an experience-dependent manner. Finally, we found that the experience-dependent shift in hippocampal long-axis activity is blocked in CA3-NR1 knock-out mice. These findings establish a cellular mechanism for the plasticity imaged in the hippocampal long-axis, suggesting how experience-dependent modifications of hippocampal activity can contribute to its mnemonic function.
Pyrolysis oil upgrading for co-processing in standard refinery units (2010)

This thesis considers the route that comprises the upgrading of pyrolysis oil (produced from lingo-cellulosic biomass) and its further co-processing in standard refineries to produce transportation fuels. In the present concept, pyrolysis oil is produced where biomass is available and then transported to a central upgrading unit. This unit is located next or inside a standard petroleum refinery, enabling the use of existing facilities. The obtained product can be further distributed using existing distribution networks. The present thesis describes and discusses pyrolysis oil upgrading by high pressure thermal treatment (HPTT) and hydrodeoxygenation (HDO), and its subsequent co-processing in lab-scale refinery units. The oil produced by HPTT had higher energy density than the feed due to its lower oxygen and water content. Conversion and transfer of water soluble organics to the oil phase was observed, increasing the energy recovery in the final product. However, severe and fast polymerisation was also observed. This polymerisation created a product with high coking tendency that could not be co-processed in lab-scale refinery units. HDO of pyrolysis oil (and fractions obtained by adding water to it) also created an oil with lower oxygen and water content. However, during HDO, polymerisation was avoided. HDO oils (with high remaining oxygen content) produced at different conditions and from various pyrolysis oil fractions, could be co-processed with Long Residue in a lab-scale catalytic cracking unit. The resulting yields to gasoline and light cycle oil (diesel precursor) were near the same as obtained using the pure fossil reference feed. The presence of such fossil co-feed enabled hydrogen transfer reactions from the fossil feed to the HDO oils components and appeared to be crucial to obtain a good product distribution. Co-processing HDO oils with straight run gas oil in a lab-scale hydrodesulphurisation unit was performed without operational problems, but competition between oxygen and sulphur removal reactions was detected. Dedicated HDO experiments showed that mass transfer resistances can limit the extent of the hydrotreating reactions (favouring in this way the extent of undesired polymerisation reactions, thus deteriorating product quality) and need careful consideration when designing demo units and industrial HDO reactors.