gebhart/patrepeval huggingface dataset:
Towards a Design Process for Computer-Aided Biomimetics (2018)

Computer-Aided Biomimetics (CAB) tools aim to support the integration of relevant biological knowledge into biomimetic problem-solving processes. Specific steps of biomimetic processes that require support include the identification, selection and abstraction of relevant biological analogies. Existing CAB tools usually aim to support these steps by describing biological systems in terms of functions, although engineering functions do not map naturally to biological functions. Consequentially, the resulting static, functional view provides an incomplete understanding of biological processes, which are dynamic, cyclic and self-organizing. This paper proposes an alternative approach that revolves around the concept of trade-offs. The aim is to include the biological context, such as environmental characteristics, that may provide information crucial to the transfer of biological information to an engineering application. The proposed design process is exemplified by an illustrative case study.
Multi-Zone Gravel Pack Techniques: Case Studies From the South China Sea Xijiang Development (1996)

Abstract Xijiang is the first Pearl River Mouth Basin Development in the South China Sea employing gravel packs. These fields, comprised of multiple-layered reservoirs, are characterized by unconsolidated, friable, and high-permeability sandstones that must be commingled for economical production. This paper will discuss the specific reservoir characteristics and parameters that affected completion scenarios in the development of these fields and how the needs for sand control, zonal isolation, high-rate production, and reduced completion duration have been addressed. Particularly significant in development of the projects has been the design of two completions systems specific to the Xijiang reservoir conditions that accomplish gravel packing and mechanical isolation of individual sands while minimizing the number of trips made into the wellbore. The single-trip dual-zone (STDZ) system is used when two zones must be gravel packed, and the multi-zone system has been employed when there are as many as 8 zones in one wellbore that must be gravel packed.
High performance S-type cathode (1997)

PolyPlus Battery Company (PPBC) is developing an advanced lithium polymer rechargeable battery based on proprietary positive electrode chemistry. In one formulation, this electrode contains elemental sulfur, either free or in association with secondary materials that promote its utilization. Batteries based on this cathode chemistry offer high steady-state (>250 W/kg) and high peak power densities (3,000 W/kg), in a low cost and environmentally benign format. High energy density, in excess of 500 Wh/kg (600 Wh/l) can also be achieved. The high power and energy densities, along with the low toxicity and low cost of materials used in the PolyPlus solid-state cells make this battery exceptionally attractive for both hybrid and electric vehicles, and for consumer electronic applications.
Parametric Analysis and Voltage Generation Performance of a Multi-directional MDOF Piezoelastic Vibration Energy Harvester (2020)

Piezoelectric vibration energy harvesting has been extensively investigated in recent years and the majority of results focus on using the cantilever beam model under base driven motion. The main focus of this paper is to perform a parametric analysis of multi degrees of freedom piezo-elastic energy harvester to optimize the capability curve exploiting crossing/veering between modes. The structure under test consists of a combination of slender beams with one or more orthogonal beam segments placed on it. The resulting combined structure exhibits bending vibration modes in orthogonal planes. The cross and veering phenomena are studied in deep, attempting to improve the resulting mechanical-electrical energy conversion of the combined structure. A numerical model of the system under investigation is developed considering also non-classical damping. A parametric analysis of the system’ s performance due to geometrical and electrical properties variations are investigated to design a broadband harvester. An experimental analysis is performed on a test rig specially built to investigate the crossing and veering phenomena effects on the resulting output voltage from the energy harvester. Numerically simulated and experimental data are compared to provide information for updating the model as well as to address the efficiency of the harvester in terms of voltage generation.
A fuzzy pattern recognition method embedded in a robot controller (2003)

We have previously proposed original membership functions building for fuzzy pattern recognition. In this paper we propose a method to build a unified membership function for one of the most important sensory functions of an intelligent robot-the robot eye, and a way to embed this method in a robot controller.
RDE-4 preferentially binds long dsRNA and its dimerization is necessary for cleavage of dsRNA to siRNA (2006)

In organisms ranging from Arabidopsis to humans, Dicer requires dsRNA-binding proteins (dsRBPs) to carry out its roles in RNA interference (RNAi) and micro-RNA (miRNA) processing. In Caenorhabditis elegans, the dsRBP RDE-4 acts with Dicer during the initiation of RNAi, when long dsRNA is cleaved to small interfering RNAs (siRNAs). RDE-4 is not required in subsequent steps, and how RDE-4 distinguishes between long dsRNA and short siRNA is unclear. We report the first detailed analysis of RDE-4 binding, using purified recombinant RDE-4 and various truncated proteins. We find that, similar to other dsRBPs, RDE-4 is not sequence-specific. However, consistent with its in vivo roles, RDE-4 binds with higher affinity to long dsRNA. We also observe that RDE-4 is a homodimer in solution, and that the C-terminal domain of the protein is required for dimerization. Using extracts from wild-type and rde-4 mutant C. elegans, we show that the C-terminal dimerization domain is required for the production of siRNA. Our findings suggest a model for RDE-4 function during the initiation of RNAi.
Acromial Morphology in Different MR Oblique Sagittal Slices: Correlation with Rotator Cuff Disorder (2009)

Purpose: On the hypothesis that the acromion morphology is changed according to the its site, we identified the morphology of the acromion on the oblique slices of MRI and we investigated the association of the acromial shape with the clinical stages of rotator cuff disorder on the magnetic resonance (MR) images. In addition, we compared the acromion morphology on MRI and simple X-rays. Material and Methods: The MR images of seventy one patients with rotator cuff disorder and who underwent arthroscopic surgery were compared with that of a control group of sixteen patients who didn't have rotator cuff disorder on MRI. On three subsequent oblique sagittal slices from the lateral edge of the acromion (S1, S2 and S3), each acromion morphology on the MRI slices was classified according to Epstein et al: flat, curved or hooked. We investigated the changing parttern of the acromion shape and we compared the acromion shape on MRI and that on simple X-rays. We classified the rotator cuff tear by the severity: bursitis, partial thickness tear or full thickness tear. We investigated which acromial type on the MRI oblique slice was associated with the severity of rotator cuff disease. Results: Changes of the acromial shape occurred in 54 patients (76.1%). The most frequent pattern was that the types are same on S1 and S2 and different on S3 (22 cases, 31.0%). The acromial type on S1 and S2 was significantly associated with the severity of rotator cuff disorder (p=0.001 and 0.022), respectively. There was no reliability of the acromial shape on MRI and roentgenography (p>0.05).
ChemInform Abstract: Room‐Temperature Alternative to the Arbuzov Reaction: The Reductive Deoxygenation of Acyl Phosphonates. (2010)

Abstract A one‐pot multistep procedure to prepare alkyl phosphonates from the commercially available acid chlorides or from acid chlorides, generated in situ from the corresponding carboxylic acids with oxalyl chloride.
Structure prediction and its applications in computational materials design (2015)

Structure prediction has proved to be a powerful tool in computational design of materials. This review summarized principles of global optimization methods applied to structure prediction. We introduced the USPEX method based on evolutionary algorithms as a tool for structure prediction. In particular, we discussed its recent progress in search for new materials with variable stoichiometry and optimal physical properties, and its extension to various low-dimensional systems.
Eag1: An Emerging Oncological Target (2008)

Emerging evidence indicates that ion channels act in a variety of physiologic and pathologic processes beyond electronic signal transmission, including in cancer. We recently found that the potassium channel Eag1 can mediate cancer progression and that a monoclonal antibody, which inhibits Eag1 action, can effectively restrict cancer cell proliferation. We discuss how Eag1 targeting may be useful in diagnostic or therapeutic settings.
A priority list based heuristic for the job shop problem: part 2 tabu search (2004)

Abstract Following a recent paper by the same author, a priority list-based tabu search heuristic is compared with the leading schedule-based tabu search heuristic of Nowicki and Smutnicki. More search neighbourhoods are required to achieve a given average makespan, but each priority list neighbourhood is searched much faster than the corresponding neighbourhood in the space of feasible schedules. Priority list-based tabu search therefore outperforms schedule-based tabu search in terms of elapsed CPU time.
High-resolution SNP mapping by denaturing HPLC (2002)

With the availability of complete genome sequences, new rapid and reliable strategies for positional cloning become possible. Single-nucleotide polymorphisms (SNPs) permit the mapping of mutations at a resolution not amenable to classical genetics. Here we describe a SNP mapping procedure that relies on resolving polymorphisms by denaturing HPLC without the necessity of determining the nature of the SNPs. With the example of mapping mutations to the Drosophila nicastrin locus, we discuss the benefits of this method, evaluate the frequency of closely linked and potentially misleading second site mutations, and demonstrate the use of denaturing high-performance liquid chromatography to identify mutations in the candidate genes and to fine-map chromosomal breakpoints. Furthermore, we show that recombination events are not uniformly dispersed over the investigated region but rather occur at hot spots.
Synthesis, Characterization, and 32P-Postlabeling of N-(Deoxyguanosin)-4-aminobiphenyl 3‘-Phosphate Adducts (2004)

The (32)P-postlabeling assay is an extremely sensitive technique for detecting carcinogen-DNA adducts. However, for the assignment of DNA adduct structures and the accurate determination of DNA adduct levels by (32)P-postlabeling, authentic adduct standards are needed. For most (32)P-postlabeling applications, such verified synthetic standard compounds are required in the form of their deoxynucleoside 3'-phosphates because they represent substrates for the polynucleotide kinase for transfer of [(32)P]phosphate from [gamma-(32)P]ATP. Three N-(deoxyguanosin)-4-aminobiphenyl 3'-phosphate adducts were prepared and fully characterized by (1)H NMR and mass spectroscopy to serve as standards for the (32)P-postlabeling assay. Apart from the C8- and the N(2)-deoxyguanosine 3'-phosphate adducts of the mutagenic human bladder carcinogen 4-aminobiphenyl (dG3'p-C8-4-ABP and dG3'p-N(2)-4-ABP), the C8-deoxyguanosine 3'-phosphate adduct of the nonmutagenic 4'-tert-butyl-4-aminobiphenyl (dG3'p-C8-4'tBu-4-ABP) was included in the study. Both C8-deoxyguanosine 3'-phosphate adducts were prepared by the in situ formation of deoxyguanosine 3'-phosphate and its subsequent reaction with the appropriate electrophilic amination agent (N-acetoxy compound). The N(2)-deoxyguanosine 3'-phosphate adduct was obtained by a modification of a previously described procedure for the synthesis of N(2)-deoxyguanosine adducts of aromatic amines. The three adduct standards were added at different concentrations to calf thymus DNA, and adduct recoveries were determined by the (32)P-postlabeling assay under conditions routinely used in the standard methodology, enhancement by nuclease P1 digestion and enhancement by butanol extraction. The dG3'p-C8-4-ABP adduct was recovered irrespective of the concentration with approximately 30% in both the standard and the butanol extraction version of the assay. Both C8-deoxyguanosine 3'-phosphate adducts were sensitive to nuclease P1 digestion resulting in recoveries of only 1-3%. In contrast, the dG3'p-N(2)-4-ABP adduct was resistant to nuclease P1 digestion; however, recovery in all three versions was poor (1-2%) resulting in a detection limit of one adduct/10(6) nucleotides. These results demonstrate that the (32)P-postlabeling assay underestimates the level of DNA adducts formed by 4-ABP and indicates that there is a need to determine the recovery for each adduct to be analyzed by the (32)P-postlabeling technique.
Directed Regression (2009)

When used to guide decisions, linear regression analysis typically involves estimation of regression coefficients via ordinary least squares and their subsequent use to make decisions. When there are multiple response variables and features do not perfectly capture their relationships, it is beneficial to account for the decision objective when computing regression coefficients. Empirical optimization does so but sacrifices performance when features are well-chosen or training data are insufficient. We propose directed regression, an efficient algorithm that combines merits of ordinary least squares and empirical optimization. We demonstrate through a computational study that directed regression can generate significant performance gains over either alternative. We also develop a theory that motivates the algorithm. 1
A First Insight into the Gonad Transcriptome of Hong Kong Catfish (Clarias fuscus) (2021)

Hong Kong catfish (<i>Clarias fuscus</i>) exhibit sexual dimorphism, particularly in body size. Due to the fast growth rate of males, the sexual size dimorphism of Hong Kong catfish has become an economically important trait. However, limited knowledge is known about the molecular mechanisms of sex determination and sex differentiation in this species. In this study, a first de novo transcriptome sequencing analysis of testes and ovaries was performed to identify sex-biased genes in Hong Kong catfish. The results showed that a total of 290,291 circular consensus sequences (CCSs) were obtained, from which 248,408 full-length non-chimeric (FLNC) reads were generated. After non-redundant analysis, a total of 37,305 unigenes were predicted, in which 34,342 unigenes were annotated with multiple public databases. Comparative transcriptomic analysis identified 5750 testis-biased differentially expressed genes (DEGs) and 6991 ovary-biased DEGs. The enrichment analysis showed that DEGs were classified into 783 Gene Ontology (GO) terms and 16 Kyoto Encyclopedia of Gene and Genome (KEGG) pathways. Many DEGs were involved with sex-related GO terms and KEGG pathways, such as oocyte maturation, androgen secretion, gonadal development and steroid biosynthesis pathways. In addition, the expression levels of 23 unigenes were confirmed to validate the transcriptomic data by quantitative real-time polymerase chain reaction (qRT-PCR). This is the first investigation into the transcriptome of Hong Kong catfish testes and ovaries. This study provides an important molecular basis for the sex determination and sex control breeding of Hong Kong catfish.
Mixed RIS-Relay NOMA-Based RF-UOWC Systems (2022)

Reconfigurable intelligent surface (RIS), non-orthogonal multiple access (NOMA), and underwater optical wireless communication (UOWC) are paradigms of technologies that drive the development of next generation communication systems. In this paper, we investigate the performance of a NOMA-based RIS-assisted hybrid radio frequency (RF)-UOWC system. The ship works as a relay that redirects the received signal to two underwater destinations simultaneously. Due to the interruption of the direct link between the base station and the ship floating on the surface of the water, communication will be carried out via an RIS fixed to an intermediate building. In this paper, we provide new analytical expressions for the outage probability (OP), asymptotic analyses of the OP, and diversity order (D) to gain insights into the system performance. The results showed that the diversity order depends on the UOWC receiver detection technique. In the end, we illustrated that the NOMA-based RIS-assisted system significantly improves the outage performance of hybrid RF-UWOC systems over a benchmark system.
주부의 직업유형과 가계소비지출구조 (1998)

The purpose of this study is to examine the effect of wife''s employment to the household expenditures by wife''s occupation. The data used in the study was taken from 1996 National Survey of Family Income and Expenditure sponsored by National Statistical O
Large-Scale Correlation Screening (2011)

This paper treats the problem of screening for variables with high correlations in high dimensional data in which there can be many fewer samples than variables. We focus on threshold-based correlation screening methods for three related applications: screening for variables with large correlations within a single treatment (autocorrelation screening); screening for variables with large cross-correlations over two treatments (cross-correlation screening); screening for variables that have persistently large auto-correlations over two treatments (persistent-correlation screening). The novelty of correlation screening is that it identifies a smaller number of variables which are highly correlated with others, as compared to identifying a number of correlation parameters. Correlation screening suffers from a phase transition phenomenon: as the correlation threshold decreases the number of discoveries increases abruptly. We obtain asymptotic expressions for the mean number of discoveries and the phase transition thresholds as a function of the number of samples, the number of variables, and the joint sample distribution. We also show that under a weak dependency condition the number of discoveries is dominated by a Poisson random variable giving an asymptotic expression for the false positive rate. The correlation screening approach bears tremendous dividends in terms of the type and strength of the asymptotic results that can be obtained. It also overcomes some of the major hurdles faced by existing methods in the literature as correlation screening is naturally scalable to high dimension. Numerical results strongly validate the theory that is presented in this paper. We illustrate the application of the correlation screening methodology on a large scale gene-expression dataset, revealing a few influential variables that exhibit a significant amount of correlation over multiple treatments.
Heat Conductive Wire Matrix Board for Light Emitting Diode (LED) Dot Matrix Display (1995)

A wire matrix has been developed for mounting LED dot matrix displays whereby insulated wires are ‘woven’ to produce a matrix that is fixed on an aluminium board with epoxy adhesive. This monolayer woven wire board simplifies the fabrication process of the display board while at the same time showing more than double the heat dissipation of conventional insulated aluminium printed circuit boards and five times that of conventional glass epoxy printed circuit boards when mounted with bare LED chips. In addition, it is suitable for high‐density and high‐brightness LED dot matrix displays.
Gefahrstoffe am Arbeitsplatz – Arbeitsplatzgrenzwert, Immissionsgrenzwert oder Innenraumrichtwert?/Hazardous substances at workplace – Occupational exposure limit, immission limit value or indoor air guide value? (2019)

Die Beurteilung der Konzentrationen von Gefahrstoffen in der Luft kann anhand verschiedener Beurteilungsmaßstäbe erfolgen. Einerseits ist dafür ausschlaggebend, ob Tätigkeiten mit Gefahrstoffen oder ohne Gefahrstoffe ausgeführt werden. Andererseits ist auch immer zu berücksichtigen, ob die Tätigkeiten im Freien, in teilweise geschlossenen oder geschlossenen Arbeitsbereichen erfolgen. Es werden einzelne Szenarien näher betrachtet und die Expositionsbeurteilung wird anhand von Arbeitsplatzgrenzwerten, Immissionsgrenzwerten und Innenraumrichtwerten dargestellt. Dabei wird insbesondere auf solche Situationen eingegangen, die sich nicht eindeutig voneinander abgrenzen lassen.
Formation of Copper Oxide Nanotextures on Porous Calcium Carbonate Templates for Water Treatment (2021)

The necessity of providing clean water sources increases the demand to develop catalytic systems for water treatment. Good pollutants adsorbers are a key ingredient, and CuO is one of the candidate materials for this task. Among the different approaches for CuO synthesis, precipitation out of aqueous solutions is a leading candidate due to the facile synthesis, high yield, sustainability, and the reported shape control by adjustment of the counter anions. We harness this effect to investigate the formation of copper oxide-based 3D structures. Specifically, the counter anion (chloride, nitrate, and acetate) affects the formation of copper-based hydroxides and the final structure following their conversion into copper oxide nanostructures over porous templates. The formation of a 3D structure is obtained when copper chloride or nitrate reacts with a <i>Sorites</i> scaffold (marine-based calcium carbonate template) without external hydroxide addition. The transformation into copper oxides occurs after calcination or reduction of the obtained Cu<sub>2</sub>(OH)<sub>3</sub>X (X = Cl<sup>-</sup> or NO<sub>3</sub><sup>-</sup>) while preserving the porous morphology. Finally, the formed <i>Sorites</i>@CuO structure is examined for water treatment to remove heavy metal cations and degrade organic contaminant molecules.
Free-Breathing and Single-Breath Hold Compressed Sensing Real-Time MRI of Right Ventricular Function in Children with Congenital Heart Disease (2023)

(1) Purpose: to compare right ventricular (RV) functional parameters in children with surgically repaired congenital heart disease (CHD) using single/double breath hold (BH) and free-breathing (FB) real-time compressed sensing (CS) cine cardiac magnetic resonance (cMRI) with standard retrospective segmented multi breath hold (RMB) cine cMRI. (2) Methods: Twenty patients with CHD underwent BH and FB, as well as RMB cine cMRI, at 3T to obtain a stack of continuous axial images of the RV. Two radiologists independently performed qualitative analysis of the image quality (rated on a 5-point scale; 1 = non-diagnostic to 5 = excellent) and quantitative analysis of the RV volume measurements. (3) Results: The best image quality was provided by RMB (4.5; range 2-5) compared to BH (3.9; range 3-5; <i>p</i> = 0.04) and FB (3.6; range 3-5; <i>p</i> < 0.01). The RV functional parameters were comparable among BH, FB, and RMB with a difference of less than 5%. The scan times for BH (44 ± 38 s, <i>p</i> < 0.01) and FB (24 ± 7 s, <i>p</i> < 0.01) were significantly reduced compared to for RMB (261 ± 68 s). (4) Conclusions: CS-FB and CS-BH real-time cine cMRI in children with CHD provides diagnostic image quality with excellent accuracy for measuring RV function with a significantly reduced scan time compared to RMB.