gebhart/patrepeval huggingface dataset:
PALAEONTOLOGIA SINICA. Series D, volume 1. GEOLOGICAL SURVEY OF CHINA, PEKIN. Fascicle I: The Cave-deposit at Sha Kuo T'un in Fengtien. By J. G. Andersson. 1923. pp. 43, 12 plates, 20 text-figures. Fascicle 2: Painted stone age pottery from the province of Honan, China. By T. J. Arne. 1925. pp. 40, 13 plates (six in colour), 63 text-figures. Fascicle 3: The human skeletal remains from the Sha Kuo T'un cave-deposit in comparison with those from Yang Shao Tsun and with recent north China skeletal material. By Davidson Black. 1925. pp. 120, 14 plates, 86 tables. - MEMOIRS OF THE GEOLOGICAL SURVEY OF CHINA. Series A, no. 5. Preliminary report on archaeological researches in Kansu. By J. G. Andersson. Pekin. 1925. pp. 56, 12 plates. (1928)

PALAEONTOLOGIA SINICA. Series D, volume 1. GEOLOGICAL SURVEY OF CHINA, PEKIN. Fascicle I: The Cave-deposit at Sha Kuo T'un in Fengtien. By J. G. Andersson. 1923. pp. 43, 12 plates, 20 text-figures. Fascicle 2: Painted stone age pottery from the province of Honan, China. By T. J. Arne. 1925. pp. 40, 13 plates (six in colour), 63 text-figures. Fascicle 3: The human skeletal remains from the Sha Kuo T'un cave-deposit in comparison with those from Yang Shao Tsun and with recent north China skeletal material. By Davidson Black. 1925. pp. 120, 14 plates, 86 tables. - MEMOIRS OF THE GEOLOGICAL SURVEY OF CHINA. Series A, no. 5. Preliminary report on archaeological researches in Kansu. By J. G. Andersson. Pekin. 1925. pp. 56, 12 plates. - Volume 2 Issue 5
A Multi-Purpose Haptic D Device for Research on Physical Human-Robot Interaction (2012)

Abstract Haptic devices are frequently used for commercial applications as well as for research purposes. High quality commercially-available devices are typically expensive, provide limited interfaceability from a software as well available as a hardware perspective and are not necessarily optimized in terms of performance. This paper presents a necessarily redesign of the Phantom® Premium haptic device that significantly improves its structural stiffness and control performance, thereby extending the usability. The device can be used as a haptic device with both impedance and admittance-type interaction controllers and also as a position-controlled robotic device.
ANOVA model based moving window approach for RtR control in high-mix semiconductor manufacturing industry (2013)

In this work, a new state estimation method based on run-to-run control for high-mix semiconductor manufacturing industry is proposed. This algorithm exerts moving window approach on the analysis of variance (ANOVA) model, MW-ANOVA approach, and employs the right pseudo-inverse of the context matrix to provide better estimate of the relative states including disturbances of each product and tool at next run. This approach takes the commonly encountered non-stationary disturbances, i.e., an integrated moving average with first order IMA(1,1) disturbance, into account. Comparing to the traditional t-EWMA algorithm, it provides better control performance, which can be verified by simulation examples.
MEMS for integrated timing and spectral processing (2009)

This paper presents a review of micro-electromechanical devices for frequency references and RF spectral processing. The application of high-Q pure silicon and AlN-on-silicon bulk acoustic wave resonators in low phase-noise reference oscillators is discussed and compensation challenges are described. Low-loss piezo-acoustic filters and high-Q tunable and switchable silver passives are presented for applications in multi-mode front-end modules and spectral processors.
Osteoinductive agents. Basic science and clinical applications. (1995)

Demineralized bone matrix (DBM) is well characterized as an osteoinductive agent. This article reviews the historical perspectives and current body of knowledge on the mechanisms of induced osteogenesis and the factors contained within DBM, which can induce bone formation. The use of DBM and osteoinductive agents to treat bone defects and nonunions in both animal models and human conditions in orthopedic and reconstructive surgery are discussed.
SCHIZOPHRENIA EPIGENETIC AGING PATTERNS REFLECT ALTERED MORTALITY AND CANCER RISKS (2019)

Abstract Schizophrenia (SZ) is associated with large increases in all-cause mortality, high smoking rates, and elevated levels of age-associated proteins—suggesting individuals with SZ may experience accelerated rates of biological aging. Yet surprisingly, multiple previous studies found no association between SZ and biological age using Horvath’s epigenetic clock, a well-recognized and validated biomarker of aging based on DNA methylation (DNAm) levels. However, numerous epigenetic clocks have been developed to date, many of which are better indicators of differential lifespan and healthspan than the original Horvath clock. Thus, we hypothesize that these epigenetic clocks may be better proxies for the presumed accelerated aging rate in SZ. Here we investigate 14 epigenetic clocks using three publicly available DNAm datasets from whole blood, comparing SZ to non-psychiatric controls (NPC). In all data sets, we find SZ age acceleration in three clocks previously shown to be most predictive of age-related morbidity and mortality risk. In contrast, two clocks developed to capture mitotic rate are decelerated in SZ, consistent with low cancer rates despite smoking observed in epidemiological studies of SZ. We use these clocks to investigate the determinants of altered aging in SZ, such as smoking, alcohol, BMI, age-associated proteins, blood cell composition, and psychotropic medications. Principal component analysis suggests mortality clock acceleration, mitotic clock deceleration, and medication effects are independent phenomena in SZ. Our study demonstrates the importance of studying the various epigenetic clocks in tandem and highlights their potential utility for understanding how mental illness influences long-term outcomes including cancer and early mortality.
Ellipsoidal concentrators for laboratory X-ray sources: Analytical approach for optimization (2013)

Extremely low intensity of most existing laboratory X-ray sources (λ ∼ 0.01–10 nm) calls for the development of collimating and concentrating optics, which allow to increase significantly the radiation power on the sample surface. The problem of optimizing concentrator parameters is analytically solved in this study. This solution allows one to determine (without any auxiliary calculations) the maximum possible efficiency of a concentrator at any wavelength and analyze the dependence of its efficiency on the source size, wavelength, the source-sample distance, etc.
Longitudinal SARS-CoV-2 infection study in a German medical school (2021)

Abstract In light of the COVID-19 pandemic, universities around the world were challenged by the difficult decision whether classes could be held face-to-face in the winter semester 20/21. The gross anatomy course is considered an essential practical element of medical school. In order to protect the participants and teaching staff and to gain more knowledge about SARS-CoV-2 infections among students during a semester with face-to-face teaching a longitudinal test study was conducted. Medical students from the first three years of medical school were also invited. Out of a total of almost 1,000 swabs, only two active asymptomatic infections were detected at the start of the semester, none during the semester. At semester start, approximately 6% of the students had antibodies. At the end of the semester, only nine seroconversions after infection in 671 individuals occurred. This was surprisingly low because a massive second wave of infections hit Germany during the same period. The conclusion therefore is that face-to-face teaching under these measures was not infection-promoting even with high incidence rates in the overall population with the SARS-CoV-2 variants present at that time period. Moreover, the results are indicative of a preventive effect of hygiene concepts together with repetitive testings before and during a semester.
Some Remarks on Theoretical Developments in Quantitative Texture Analysis and on theOptimal Calculation of Harmonic Quantities With High Precision (1988)

After a short characterization of the most important stages of evolution of quantitative texture analysis as they are seen by the author, problems of simplification and improvement of precision are discussed especially concerning numerical calculations using the harmonic apparatus.
Phosphorylcholine determinants in six pneumococcal capsular polysaccharides detected by monoclonal antibody (1984)

The presence of phosphorylcholine in pneumococcal capsular polysaccharides was examined by using monoclonal antiphosphorylcholine antibody. Of the 83 known capsular types of Streptococcus pneumoniae, 6 types, viz., 24A, 27, 28F, 28A, 32F, and 32A, gave a positive capsular reaction (quellung) which could be inhibited by phosphorylcholine. The capsular polysaccharides of these six types, therefore, contain phosphorylcholine.
Next generation Intel&#x00AE; micro-architecture (Nehalem) clocking architecture (2008)

This paper describes the next generation Intel <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">reg</sup> micro-architecture (Nehalem) 45 nm IA processorpsilas core and I/O clocking architecture. Among the highlights are: configurable clocking, fastlock low-skew PLLs, high reference clock frequencies, analog supply tracking system, adaptive frequency clocking, low jitter Intel <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">reg</sup> QuickPath interconnect and Intel <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">reg</sup> QuickPath memory controller clock generation, and jitter-attenuating DLLs.
Response of recurrent BRAFV600E mutated ganglioglioma to Vemurafenib as single agent (2014)

Our experience underline the importance of understanding the driver molecular alterations of LGG and suggests a role for Vemurafenib in the treatment of pediatric GG not amenable of complete surgical resection.
Lipid peroxidation during n−3 fatty acid and vitamin E supplementation in humans (1997)

The purpose of this study was to investigate in healthy humans the effect of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) intake, alone or in combination with dL-alpha-tocopherol acetate (vitamin E) supplements on lipid peroxidation. Eighty men were randomly assigned in a double-blind fashion to take daily for 6 wk either menhaden oil (6.26 g, n-3 fatty acids) or olive oil supplements with either vitamin E (900 IU) or its placebo. Antioxidant vitamins, phospholipid composition, malondialdehyde (MDA), and lipid peroxides were measured in the plasma at baseline and week 6. At the same time, breath alkane output was measured. Plasma alpha-tocopherol concentration increased in those receiving vitamin E (P < 0.0001). In those supplemented with n-3 fatty acids, EPA and DHA increased in plasma phospholipids (P < 0.0001) and plasma MDA and lipid peroxides increased (P < 0.001 and P < 0.05, respectively). Breath alkane output did not change significantly and vitamin E intake did not prevent the increase in lipid peroxidation during menhaden oil supplementation. The results demonstrate that supplementing the diet with n-3 fatty acids resulted in an increase in lipid peroxidation, as measured by plasma MDA release and lipid peroxide products, which was not suppressed by vitamin E supplementation.
Identification of telomerase RNAs in species of the Yarrowia clade provides insights into the co-evolution of telomerase, telomeric repeats and telomere-binding proteins (2019)

Telomeric repeats in fungi of the subphylum Saccharomycotina exhibit great inter- and intra-species variability in length and sequence. Such variations challenged telomeric DNA-binding proteins that co-evolved to maintain their functions at telomeres. Here, we compare the extent of co-variations in telomeric repeats, encoded in the telomerase RNAs (TERs), and the repeat-binding proteins from 13 species belonging to the Yarrowia clade. We identified putative TER loci, analyzed their sequence and secondary structure conservation, and predicted functional elements. Moreover, in vivo complementation assays with mutant TERs showed the functional importance of four novel TER substructures. The TER-derived telomeric repeat unit of all species, except for one, is 10 bp long and can be represented as 5'-TTNNNNAGGG-3', with repeat sequence variations occuring primarily outside the vertebrate telomeric motif 5'-TTAGGG-3'. All species possess a homologue of the Yarrowia lipolytica Tay1 protein, YlTay1p. In vitro, YlTay1p displays comparable DNA-binding affinity to all repeat variants, suggesting a conserved role among these species. Taken together, these results add significant insights into the co-evolution of TERs, telomeric repeats and telomere-binding proteins in yeasts.
Micro- and Macro- Borderless HBPT Surgery Using Novel 3D-4K Video System (2018)

Yagi, Shintaro MD, FACS; Ito, Takashi MD, PhD; Ogawa, Eri MD, PhD; Kasai, Yosuke MD, PhD; Shirai, Hisaya MD; Yao, Siyuan MD; Masano, Yuki MD; Uemoto, Shinji MD, PhD; Kobayashi, Eiji MD, PhD Author Information
Computer-aided modelling of the structures and metal-ion affinities of chelating agents (1988)

Conference Article| October 01 1988 Computer-aided modelling of the structures and metal-ion affinities of chelating agents DAVID J. BARLOW; DAVID J. BARLOW 1Department of Pharmacy, King's College London, Manresa Road, London SW3 6LX, U.K. Search for other works by this author on: This Site PubMed Google Scholar ROBERT C. HIDER; ROBERT C. HIDER 1Department of Pharmacy, King's College London, Manresa Road, London SW3 6LX, U.K. Search for other works by this author on: This Site PubMed Google Scholar SURINDER SINGH; SURINDER SINGH 1Department of Pharmacy, King's College London, Manresa Road, London SW3 6LX, U.K. Search for other works by this author on: This Site PubMed Google Scholar KEITH S. WIBLEY KEITH S. WIBLEY 1Department of Pharmacy, King's College London, Manresa Road, London SW3 6LX, U.K. Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1988) 16 (5): 835–836. https://doi.org/10.1042/bst0160835 Article history Received: April 12 1988 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation DAVID J. BARLOW, ROBERT C. HIDER, SURINDER SINGH, KEITH S. WIBLEY; Computer-aided modelling of the structures and metal-ion affinities of chelating agents. Biochem Soc Trans 1 October 1988; 16 (5): 835–836. doi: https://doi.org/10.1042/bst0160835 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1988 Biochemical Society1988 Article PDF first page preview Close Modal You do not currently have access to this content.
Bid preparation for earthmoving operations (2002)

This paper presents a computer system developed to assist earthmoving contractors in preparing proposals. It can also be used by owners and (or) their agents to plan and estimate the cost and duration of earthmoving projects. This is particularly useful for large projects where owners need to define a feasible scope of work that suits their budgets and operating plans. The system has been developed utilizing computer simulation. This paper provides an overview of the developed system and briefly describes its basic components, focusing primarily on the development of the system's database and the procedure used to account for indirect cost components of this class of projects. The paper also demonstrates the capabilities of the developed system in selecting most-suitable equipment fleets, from available equipment, that meet the terms and conditions outlined in bid documents. A project example is analyzed to demonstrate the essential features of the developed system.Key words: bid preparation, earthmoving, equipment database, indirect cost, computer simulation.
A General Synthetic Method for 2',3'-Dideoxynucleosldes: Total Synthetic Approach (1989)

Abstract A general method for the total synthesis of 2′,3′dideoxynucleosides is described.
An off-line cursive handwriting recognition system (1998)

Describes a complete system for the recognition of off-line handwriting. Preprocessing techniques are described, including segmentation and normalization of word images to give invariance to scale, slant, slope and stroke thickness. Representation of the image is discussed and the skeleton and stroke features used are described. A recurrent neural network is used to estimate probabilities for the characters represented in the skeleton. The operation of the hidden Markov model that calculates the best word in the lexicon is also described. Issues of vocabulary choice, rejection, and out-of-vocabulary word recognition are discussed.
Cold atmospheric plasma increases IBRV titer in MDBK cells by orchestrating the host cell network (2021)

Enhancing virus multiplication could assist in the rapid production of vaccines against viral diseases. Cold atmospheric plasma (CAP), a physical approach relying on reactive oxygen species to achieve the desirable cellular outcome, was shown to be effective in enhancing virus propagation, where bovine rhinotrachieitis virus and Madin-Darby Bovine Kidney cells were used as the modeling virus and cell line, respectively. CAP was shown to create synergies with virus infection in arresting host cells at the G2/M stage, decreasing cell membrane potential, increasing intracellular calcium level, and inducing selective autophagy. In addition, CAP was demonstrated to suppress virus-triggered immunogenic signaling as evaluated by IRF7 expression. We presented evidences on CAP-triggered maximization of host resources toward virus multiplication that is advantageous for viral vaccine production, and opened a novel regime for applying CAP in the sector of medical care and health.
Application of MIMO DF equalization to high-speed off-chip communication (2015)

In this contribution, we present a multiple-input multiple-output (MIMO) equalizer with decision feedback (DF) for high-speed chip-to-chip communication. We derive an elegant closed-form expression for the minimum mean square error (MMSE) equalization filters and show that the application of MIMO DF equalization (DFE) allows to significantly improve the reliability of high-speed communication over low-cost electrical interconnects.
Optimizing LLVM pass sequences with shackleton (2022)

In this paper we explore the novel application of a linear genetic programming framework, Shackleton, to optimizing sequences of LLVM optimization passes. The algorithm underpinning Shackleton is discussed, with an emphasis on the effects of different features unique to the framework when applied to LLVM pass sequences. Combined with analysis of different hyperparameter settings, we report the results on automatically optimizing pass sequences with Shackleton for two software applications at differing complexity levels. Finally, we reflect on the advantages and limitations of our current implementation and lay out a path for further improvements. These improvements aim to surpass hand-crafted solutions with an automatic discovery method for an optimal pass sequence.
A Thermodynamic Preference of Chiral N-Methanesulfonyl and N-Arenesulfonyl 2,3-cis-3-Alkyl-2-Vinylaziridines over Their 2,3-Trans-Isomers:  Useful Palladium(0)-Catalyzed Equilibration Reactions for the Synthesis of (E)-Alkene Dipeptide Isosteres (1997)

Palladium(0)-catalyzed reactions of N-methanesulfonyl- or N-(arenesulfonyl)-3-alkyl-2-vinylaziridines reveal that 2,3-cis-isomers are more stable than the corresponding 2,3-trans-isomers in accord with ab initio calculations. A highly stereoselective synthetic route to (E)-alkene dipeptide isosteres having desired stereochemistries from 2,3-cis-3-isobutyl-2-vinylaziridine by the use of organocopper chemistry is also presented.
AI Testing Framework for Next-G O-RAN Networks: Requirements, Design, and Research Opportunities (2022)

Openness and intelligence are two enabling features to be introduced in next generation wireless networks, e.g. Beyond 5G and 6G, to support service heterogeneity, open hardware, optimal resource utilization, and on-demand service deployment. The open radio access network (O-RAN) is a promising RAN architecture to achieve both openness and intelligence through virtualized network elements and well-defined interfaces. While deploying artificial intelligence (AI) models is becoming easier in O-RAN, one significant challenge that has been long neglected is the comprehensive testing of their performance in realistic environments. This article presents a general automated, distributed and AI-enabled testing framework to test AI models deployed in O-RAN in terms of their decision-making performance, vulnerability and security. This framework adopts a master-actor architecture to manage a number of end devices for distributed testing. More importantly, it leverages AI to automatically and intelligently explore the decision space of AI models in O-RAN. Both software simulation testing and software-defined radio hardware testing are supported, enabling rapid proof of concept research and experimental research on wireless research platforms.
Effect of Chemical Oxidation on the Sorption Tendency of Dissolved Organic Matter to a Model Hydrophobic Surface (2014)

The application of chemical oxidants may alter the sorption properties of dissolved organic matter (DOM), such as humic and fulvic acids, proteins, polysaccharides, and lipids, affecting their fate in water treatment processes, including attachment to other organic components, activated carbon, and membranes (e.g., organic fouling). Similar reactions with chlorine (HOCl) and bromine (HOBr) produced at inflammatory sites in vivo affect the fate of biomolecules (e.g., protein aggregation). In this study, quartz crystal microbalance with dissipation monitoring (QCM-D) was used to evaluate changes in the noncovalent interactions of proteins, polysaccharides, fatty acids, and humic and fulvic acids with a model hydrophobic surface as a function of increasing doses of HOCl, HOBr, and ozone (O3). All three oxidants enhanced the sorption tendency of proteins to the hydrophobic surface at low doses but reduced their sorption tendency at high doses. All three oxidants reduced the sorption tendency of polysaccharides and fatty acids to the hydrophobic surface. HOCl and HOBr increased the sorption tendency of humic and fulvic acids to the hydrophobic surface with maxima at moderate doses, while O3 decreased their sorption tendency. The behavior observed with two water samples was similar to that observed with humic and fulvic acids, pointing to the importance of these constituents. For chlorination, the highest sorption tendency to the hydrophobic surface was observed within the range of doses typically applied during water treatment. These results suggest that ozone pretreatment would minimize membrane fouling by DOM, while chlorine pretreatment would promote DOM removal by activated carbon.