gebhart/patrepeval huggingface dataset:
Realization of the Functional Model of the Software Radar Receiver (2018)

In this paper is presented the practical realization of functional model of software radar receiver on the PXI platform. All blocks after IQ demodulator and ending with display are programmed in MATLAB® software, then projected in Lab VIEW and at the end implemented on the PXI platform. Realization of the processing of radar signals in real time is presented. Comparative analysis of the results of target detection of one real radar device and realized functional model on the appropriate hardware components is shown.
Oligomerization of the 17‐kDa peptide‐binding domain of the molecular chaperone HSC70 (1999)

Crystallographic and biochemical studies have indicated that the peptide-binding site of the molecular chaperone HSC70 is located in a small subdomain comprising a beta-sheet motif followed by a helical region, and there is some evidence of the involvement of this site in oligomerization of the protein. To determine the structure of this subdomain in solution and examine its involvement in oligomerization of HSC70, a 17-kDa protein (residues 385-540 of HSC70) consisting mainly of the peptide-binding site was constructed and analyzed for oligomerization properties. This small domain was found to bind peptides and to form oligomers in solution, probably tetramers, which dissociated into monomers on peptide binding in a manner comparable with that observed for the whole protein. Furthermore, in the 60-kDa fragment of HSC70, which is composed of the 17-kDa domain and the 44-kDa ATPase domain, not only were the oligomerization properties conserved, but dissociation of multimeric species into monomers on ATP binding also occurred and peptide stimulation of ATPase activity was restored. These results indicate that the isolated 17-kDa peptide-binding domain is necessary and sufficient for oligomerization of the whole protein, suggesting that the peptide-binding site may be involved in the oligomerization process.
Versatile Reactivity of Half-Sandwich Rhodium(III) Iminophosphonamide Complexes (2022)

Novel 18e̅ and 16e̅ pentamethylcyclopentadienyl rhodium(III) complexes [(η<sup>5</sup>-C<sub>5</sub>Me<sub>5</sub>)RhX(NPN)] (<b>1a,b</b>, X = Cl; <b>2a-c</b>, X = PF<sub>6</sub>, BAr<sub>4</sub><sup>F</sup>) with chelating zwitterionic iminophosphonamide (NPN) ligands (Ph<sub>2</sub>P(NR)(NR'); <b>a</b>, R = R' = <i>p</i>-Tol; <b>b</b>, R = <i>p</i>-Tol, R' = Me; <b>c</b>, R = R' = Me) were synthesized and characterized by single-crystal X-ray diffraction. In the 16e̅ complexes <b>2</b>, the rhodium (Rh) atom is efficiently stabilized by π-donation of unshared N electrons, thus hampering coordination of the external ligands and rendering the 18e̅ complexes labile. Due to low coordination enthalpy, the cationic 18e̅ monocarbonyl and pyridine adducts <b>2a·L</b> are stable only at low temperatures. At room temperature, <b>2·CO</b> adducts readily give stable carbonyl-carbamoyl complexes [(η<sup>5</sup>-C<sub>5</sub>Me<sub>5</sub>)Rh(CO){(CO(NR')Ph<sub>2</sub>P(NR)}]<sup>+</sup> (<b>4</b>) formed as a result of CO insertion into the Rh-N bond, thus showing high nucleophilicity of the N atoms in 18e̅ complexes. High basicity of the Na<sup>+</sup>NPN<sup>-</sup> precursors caused side deprotonation of the η<sup>5</sup>-C<sub>5</sub>Me<sub>5</sub> ligand during the synthesis of <b>1</b> that yields unstable fulvene Rh(I) complexes [(η<sup>4</sup>-C<sub>5</sub>Me<sub>4</sub>CH<sub>2</sub>)Rh{Ph<sub>2</sub>P(NR)(NR')<sub>2</sub>}] (<b>3a,b</b>). Complex <b>3a</b> undergoes a facile reaction with isoprene to yield an unusual [(η<sup>5</sup>:η<sup>1</sup>-C<sub>5</sub>Me<sub>4</sub>(CH<sub>2</sub>)C(Me)═CHCH<sub>2</sub>)Rh(NPN)] complex─the first example of intermolecular 1,4-metallacycloaddition of diene to the Rh-fulvene complex.
Real-time adaptive QoS prediction using approximate matrix multiplication (2018)

We introduce a novel QoS prediction model as a real-time support for the selection of atomic service candidates based on their QoS properties while constructing composite applications. The proposed approach satisfies the following requirements: (i) fast and accurate prediction of QoS values and (ii) adaptability with respect to environment changes. The model precomputes the similarities between users and services using approximate matrix multiplication to reduce the time complexity. When calculating a prediction for a user-service pair, the model considers similar users and services, but enhances the prediction accuracy by incorporating the number of observed records. Time complexity is further reduced by storing the lists of similar users and services which are updated in real-time. The model adapts to the changing environment: newer records are set to have greater influence on the predictions. The experiments conducted on relevant service-oriented datasets show advantages of the proposed model in accuracy and time performance.
Impact of 3D stacking on the TSV-induced stress and the CMOS characteristics (2017)

We investigated the impact of the stress induced by 3D stacking structure and through-silicon vias (TSV) on characteristics of CMOS. The 3D stacking structure was found to induce considerably large stress on the Si substrate compared to stress induced by TSV. The change of CMOS characteristics was calculated using a simple method of device simulation. A considerably large shift of the drain current of p-MOS near the TSV was predicted and confirmed by the measurement. The effect of stress induced by the stacking structures was not negligible as well as the well-known effect by TSV and should be considered for the design of advanced 3D-LSI systems.
Complexation and Separation of Alkylaromatics with Copper(l) Trifluoromethanesulfonate (1973)

Abstract A novel mode of complexation of aromatics has been observed in the case of copper(I) triflate. Further, it has been found that in the solid the spatial demands of the inorganic matrix dictates a unique stability ordering of the alkylaromatics based on their shape more than on their p-basicity. This property can be the basis of an efficient means of separating isomers; for instance, in isolating p-xylene from the other eight-carbon arenes. Brief attention is focused upon the mechanism of the ligand exchange reaction via which the separating ability is manifested.
Effect of Cyclophosphamide Pretreatment on Defective Delayed-Type Hypersensitivity in Autoimmune-Prone MRL Mice (1989)

Autoimmune MRL mice develop a poor delayed-type hypersensitivity (DTH) after BCG cell wall (BCG CW) immunization. To test the possible participation of suppressor cells on DTH induction, MRL/MpJ-lpr/lpr (MRL-lpr) and MRL/MpJ-+/+ (MRL-+/+) mice were pretreated with cyclophosphamide (Cy) 4 days before the immunization. The footpad reaction to the purified protein derivative of tuberculin (PPD) was enhanced remarkably by Cy pretreatment in both MRL-lpr and MRL-+/+ mice. In addition, the lymph node cells obtained from nonpretreated MRL-lpr and MRL-+/+ mice at 7 days after BCG CW immunization suppressed the DTH induction of Cy-pretreated MRL-+/+ mice. On the other hand, a positive proliferative response to PPD in vitro was seen only in the cells from Cy-pretreated MRL-+/+ and younger MRL-lpr mice, but not in the cells of nonpretreated MRL-+/+ or both pretreated and nonpretreated older MRL-lpr mice. Removal of B220-positive cells from the lymph node cell populations of Cy-pretreated MRL-lpr mice restored PPD responsiveness, but the same treatment had no effect on the cells from nonpretreated MRL-lpr mice. The results suggest that DTH responses to PPD in MRL mice immunized with BCG CW are regulated by Cy-sensitive suppressor cells. These suppressor cells occur in MRL mice irrespective of whether they carry the lpr gene. And it is also demonstrated that MRL-lpr mice have TDTH precursor cells in a sufficient number for TDTH production even after expressing lymphadenopathy.
Evidence for the Presence of a Specific Ganglioside GMl/Valinomycin Complex in Mixed Monolayers (1991)

The effect of a negatively charged mono-sialoglyco-sphingolipid (GM1-ganglioside) on the molecular organization and on physiochemical properties of lipid/peptide (valinomycin) systems was investigated in monolayers at the air/water interface. At a high molar fraction of GM1, the surface pressure/area isotherms of the two-component films of the system GM1/valinomycin and the isotherm of the pure ganglioside monolayer are identical concerning the space requirement of the molecules and thereby the packing of the monolayer. Using space-filling molecular models, a simple calculation gives the theoretical amount of 4.5 ganglioside molecules associated with one molecule of the depsipeptide valinomycin. The average surface potential indicates, that valinomycin, interacting with the polar head group of GM1, becomes partly embedded within the lipid interface. For GM1/eicosanol and valinomycin/eicosanol mixtures, the agreement between theory and experimental data strongly supports the model of ideal mixing without any molecular interactions between the different components. The results suggest the formation of a ganglioside/valinomycin complex with simultaneous alteration of the surface potential and molecular structure of the single components.
ChemInform Abstract: Transformation of Vitamin B6 to (+)‐Deoxypyridinoline, a Useful Biochemical Marker for Diagnosis of Bone Diseases. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Shear and Longitudinal Acoustic Communication and Power Transfer Through Plates Using Acoustic Wedges (2014)

Techniques for wireless acoustic communication and energy transfer along steel plates and piping to avoid physical penetrations and wire feed-throughs are presented. Longitudinal and shear acoustic waves (polarized in the direction of the plate/pipe wall thickness) transmitted into steel plates using steel wedges are analyzed using finite-element analysis. Propagation of steady-state waves at frequencies of 1 MHz in steel plates using triangular steel wedges with varying wave launch angles were used, where the steel plate was bounded by cement on one side and engine oil on the other. Successful simulation was achieved at large axial distance from the transmitting wedge with reception into a second reversed wedge, which is applicable for both power and data transmissions. At a distance of 0.41 m the energy transfer efficiency was seen to increase with increasing launch angle to 0.1 % for shear waves and 0.03 % for longitudinal waves when operating with an 80 degree wedge.
G385 Can the presence of antenatal hydronephrosis or family history of vesicoureteric reflux predict significant renal abnormality? (2016)

<h3>Aims</h3> Renal tract dilatation is commonly detected during antenatal anomaly scanning. This can, however, be a transient phenomenon which resolves on postnatal scanning. There is some debate regarding which babies require postnatal scanning in order to detect significant abnormalities, whilst avoiding over-investigation and unnecessary parental anxiety. Currently all babies with antenatal hydronephrosis (ANHN) born within our trust have a screening ultrasound scan within the first 4 weeks of life. As part of the process of designing a regional protocol for investigation of antenatal renal abnormalities we wanted to determine which risk factors were more predictive of significant postnatal pathology. <h3>Methods</h3> We carried out a computer search using the hospital’s radiology IT system in June 2014 to list all babies born between the 1st of March and 31st of August 2013 who had renal imaging carried out. We then looked at the request forms to determine the reason for the request, focussing specifically on babies with ANHN or a family history of vesicoureteric reflux (VUR). We also looked at the results and timing of each investigation performed. <h3>Results</h3> 186 patients had renal imaging carried out, 18 of these (9.7%) were scanned due to ANHN and 25 (13.4%) had a family history of VUR only. Of the 18 babies with ANHN, one had PUJ obstruction, four had grades 3–5 VUR, one had poor drainage, one had a duplex kidney and one had a multicystic dysplastic kidney. All patients with significant pathology had a renal pelvis diameter of ≥10 mm on postnatal scans (when recorded). Seven patients had RPD ≥10 mm on the first scan and of these three (42.9%) had significant abnormalities. Of the 25 patients with a family history of VUR two had grade 1 VUR and one had grade 2 VUR. <h3>Conclusions</h3> A renal pelvis diameter of greater than or equal to 10mm postnatally is a good predictor of significant renal pathology. A family history of VUR is less predictive of significant renal pathology.
The Molecular Chaperone TRiC/CCT Binds to the Trp-Asp 40 (WD40) Repeat Protein WDR68 and Promotes Its Folding, Protein Kinase DYRK1A Binding, and Nuclear Accumulation (2014)

Trp-Asp (WD) repeat protein 68 (WDR68) is an evolutionarily conserved WD40 repeat protein that binds to several proteins, including dual specificity tyrosine phosphorylation-regulated protein kinase (DYRK1A), MAPK/ERK kinase kinase 1 (MEKK1), and Cullin4-damage-specific DNA-binding protein 1 (CUL4-DDB1). WDR68 affects multiple and diverse physiological functions, such as controlling anthocyanin synthesis in plants, tissue growth in insects, and craniofacial development in vertebrates. However, the biochemical basis and the regulatory mechanism of WDR68 activity remain largely unknown. To better understand the cellular function of WDR68, here we have isolated and identified cellular WDR68 binding partners using a phosphoproteomic approach. More than 200 cellular proteins with wide varieties of biochemical functions were identified as WDR68-binding protein candidates. Eight T-complex protein 1 (TCP1) subunits comprising the molecular chaperone TCP1 ring complex/chaperonin-containing TCP1 (TRiC/CCT) were identified as major WDR68-binding proteins, and phosphorylation sites in both WDR68 and TRiC/CCT were identified. Co-immunoprecipitation experiments confirmed the binding between TRiC/CCT and WDR68. Computer-aided structural analysis suggested that WDR68 forms a seven-bladed β-propeller ring. Experiments with a series of deletion mutants in combination with the structural modeling showed that three of the seven β-propeller blades of WDR68 are essential and sufficient for TRiC/CCT binding. Knockdown of cellular TRiC/CCT by siRNA caused an abnormal WDR68 structure and led to reduction of its DYRK1A-binding activity. Concomitantly, nuclear accumulation of WDR68 was suppressed by the knockdown of TRiC/CCT, and WDR68 formed cellular aggregates when overexpressed in the TRiC/CCT-deficient cells. Altogether, our results demonstrate that the molecular chaperone TRiC/CCT is essential for correct protein folding, DYRK1A binding, and nuclear accumulation of WDR68.
Discrete-Event Modeling and Simulation (2010)

Collecting the work of the foremost scientists in the field, Discrete-Event Modeling and Simulation: Theory and Applications presents the state of the art in modeling discrete-event systems using the discrete-event system specification (DEVS) approach. It introduces the latest advances, recent extensions of formal techniques, and real-world examples of various applications. The book covers many topics that pertain to several layers of the modeling and simulation architecture. It discusses DEVS model development support and the interaction of DEVS with other methodologies. It describes different forms of simulation supported by DEVS, the use of real-time DEVS simulation, the relationship between DEVS and graph transformation, the influence of DEVS variants on simulation performance, and interoperability and composability with emphasis on DEVS standardization. The text also examines extensions to DEVS, new formalisms, and abstractions of DEVS models as well as the theory and analysis behind real-world system identification and control. To support the generation and search of optimal models of a system, a framework is developed based on the system entity structure and its transformation to DEVS simulation models. In addition, the book explores numerous interesting examples that illustrate the use of DEVS to build successful applications, including optical network-on-chip, construction/building design, process control, workflow systems, and environmental models. A one-stop resource on advances in DEVS theory, applications, and methodology, this volume offers a sampling of the best research in the area, a broad picture of the DEVS landscape, and trend-setting applications enabled by the DEVS approach. It provides the basis for future research discoveries and encourages the development of new applications.
Red‐Emissive Carbon Dots for Fluorescent, Photoacoustic, and Thermal Theranostics in Living Mice (2015)

Novel red-emissive carbon-dots (C-dots) with broad absorption in the region from 400 to 750 nm are prepared from polythiophene phenylpropionic acid. Upon near infrared laser irradiation, the red-emissive C-dots show strong photoacoustic response and high photothermal conversion efficiency (η ≈ 38.5%). These unique properties enable the C-dots to act as multifunctional fluorescent, photoacoustic, and thermal theranostics for simultaneous diagnosis and therapy of cancer. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Three‐phase voltage‐fed type PWM power converter via power factor control (1991)

Abstract Recently, the voltage‐fed type PWM converters have been investigated for their ideal and inherent properties as a dc power source. However, the current control system generally used may be somewhat complicated due to dc voltage detection. We propose here a simple control system of the PWM converter using the power factor control in which dc voltage detection is not always needed. In this system, the dc voltage is given by the line voltage and the modulating index of the PWM converter. The principle of the PWM control system is shown at first. From the simplified circuit model and its phasor diagrams, some basic relations of the PWM converter system are obtained and some fundamental characteristics are shown. From these investigations, it is seen that the phase control region is restricted to a certain angle, which depends on the setting power factor, the modulating bypass index of the PWM and the load. Under the operating condition of unity power factor, it is given by ±π/4 for both the converting and inverting operations. The system can be operated over the all‐control range of the modulating index by restricting the angle to this critical value for the angle over this control range. The ideal operating characteristics as a dc power source can be verified by some experimental results, including the operating waveforms of line current, the steady state characteristics and the transient response between both operations of the converter and inverter. In this system it is simple to construct the control circuit; it also has some inherent and excellent characteristics as a voltage fed type dc power source. This control system may be applicable to any types of PWM converter used today.
Meningococcal infections. 3. Studies of group A polysaccharide vaccines. (1971)

Studies with 4 lots of group A meningococcal polysaccharides in 458 adult human volunteers showed that such vaccines are nontoxic and highly immunogenic. Comparisons of jet injection and subcutaneous (needle) methods of administration showed that both were equally immunogenic.
Knowledge Acquisition Method Based on Singular Value Decomposition for Human Motion Analysis (2014)

The knowledge remembered by the human body and reflected by the dexterity of body motion is called embodied knowledge. In this paper, we propose a new method using singular value decomposition for extracting embodied knowledge from the time-series data of the motion. We compose a matrix from the time-series data and use the left singular vectors of the matrix as the patterns of the motion and the singular values as a scalar, by which each corresponding left singular vector affects the matrix. Two experiments were conducted to validate the method. One is a gesture recognition experiment in which we categorize gesture motions by two kinds of models with indexes of similarity and estimation that use left singular vectors. The proposed method obtained a higher correct categorization ratio than principal component analysis (PCA) and correlation efficiency (CE). The other is an ambulation evaluation experiment in which we distinguished the levels of walking disability. The first singular values derived from the walking acceleration were suggested to be a reliable criterion to evaluate walking disability. Finally we discuss the characteristic and significance of the embodied knowledge extraction using the singular value decomposition proposed in this paper.
HIF-1α promotes autophagic proteolysis of Dicer and enhances tumor metastasis (2017)

HIF-1α, one of the most extensively studied oncogenes, is activated by a variety of microenvironmental factors. The resulting biological effects are thought to depend on its transcriptional activity. The RNAse enzyme Dicer is frequently downregulated in human cancers, which has been functionally linked to enhanced metastatic properties; however, current knowledge of the upstream mechanisms regulating Dicer is limited. In the present study, we identified Dicer as a HIF-1α-interacting protein in multiple types of cancer cell lines and different human tumors. HIF-1α downregulated Dicer expression by facilitating its ubiquitination by the E3 ligase Parkin, thereby enhancing autophagy-mediated degradation of Dicer, which further suppressed the maturation of known tumor suppressors, such as the microRNA let-7 and microRNA-200b. Consequently, expression of HIF-1α facilitated epithelial-mesenchymal transition (EMT) and metastasis in tumor-bearing mice. Thus, this study uncovered a connection between oncogenic HIF-1α and the tumor-suppressive Dicer. This function of HIF-1α is transcription independent and occurs through previously unrecognized protein interaction-mediated ubiquitination and autophagic proteolysis.
On Erdős and Sárközy's sequences with Property P (2016)

A sequence $A$ of positive integers having the property that no element $a_i \in A$ divides the sum $a_j+a_k$ of two larger elements is said to have `Property P'. We construct an infinite set $S\subset \mathbb{N}$ having Property P with counting function $S(x)\gg\frac{\sqrt{x}}{\sqrt{\log x}(\log\log x)^2(\log \log \log x)^2}$. This improves on an example given by Erdős and Sárközy with a lower bound on the counting function of order $\frac{\sqrt{x}}{\log x}$.
Acoustique physiologique (2009)

Après la Seconde Guerre mondiale, l’acoustique physiologique, et plus spécialement, l’analyse du fonctionnement de l’oreille interne étaient très délaissées dans notre pays ; seuls quelques rares médecins otorhinolaryngologistes s’efforçaient de faire progresser la physiopathologie de l’audition. C’est au neurophysiologiste Jean-Paul Legouix (1922-2009), chercheur au CNRS – qui travailla au Collège de France de 1960 à 1987 d’abord dans la chaire de Neurophysiologie générale d’Alfred Fessard (...