gebhart/patrepeval huggingface dataset:
Probiotic Bacteria in the Management of Atopic Disease: Underscoring the Importance of Viability (2003)

Supplementation of infant formulas with viable but not heat-inactivated LGG is a potential approach for the management of atopic eczema and cow's milk allergy.
The role of standardization in the development of next generation large space telescopes (2021)

Astronomy has always been a technology driven science. This drive to ever greater sensitivity and performance is placing great pressure on the development community to meet this ongoing need. Extrapolating demand indicates a fundamental problem of affordability and timely development for both space and ground based systems. We note, that this trend is not unique to UV/VIS band. Other systems such as very long baseline interferometry in space leads to the need of large aperture radio telescopes, gravitational wave experiments like the Laser Interferometer Space Antenna (LISA) and occulter and starshade missions for coronography demand for high performance at acceptable cost. This begs the question, what can be done about it? In this initial paper, we plan to explore the roles of standardization, specialization and trans-national partnerships to realize future system design and implementation. We conclude our discussion with examples of areas where standardization in hardware and engineering approaches will improve productivity to help realize the next generation of cutting edge systems.
Calibration of GOES-Derived Solar Radiation Data Using a Distributed Network of Surface Measurements in Florida, USA (2008)

Solar radiation data are critically important for the estimation of evapotranspiration. Analysis of visible-channel data derived from Geostationary Operational Environmental Satellites (GOES) using radiative transfer modeling has been used to produce spatially- and temporally-distributed datasets of solar radiation. An extensive network of (pyranometer) surface measurements of solar radiation in the State of Florida has allowed refined calibration of a GOES-derived daily integrated radiation data product. This refinement of radiation data allowed for corrections of satellite sensor drift, satellite generational change, and consideration of the highly-variable cloudy conditions that are typical of Florida. To aid in calibration of a GOES-derived radiation product, solar radiation data for the period 1995–2004 from 58 field stations that are located throughout the State were compiled. The GOES radiation product was calibrated by way of a three-step process: 1) comparison with ground-based pyranometer measurements on clear reference days, 2) correcting for a bias related to cloud cover, and 3) deriving month-by-month bias correction factors. Pre-calibration results indicated good model performance, with a station-averaged model error of 2.2 MJ m–2 day–1 (13 percent). Calibration reduced errors to 1.7 MJ m–2 day–1 (10 percent) and also removed time- and cloudiness-related biases. The final dataset has been used to produce Statewide evapotranspiration estimates.
Serum acetylcholinesterase level in the patients of opioid (brown sugar) dependence. (1992)

The authors compared the serum acetylcholinesterase level in the patients of brown sugar dependence and the normal volunteers. Significantly lower level of serum acetylcholinesterase was found in patients of brown sugar dependence.
Handbook of Nanophysics (2010)

Many bottom-up and top-down techniques for nanomaterial and nanostructure generation have enabled the development of applications in nanoelectronics and nanophotonics.&nbsp; Handbook of Nanophysics: Nanoelectronics and Nanophotonics explores important recent applications of nanophysics in the areas of electronics and photonics. Each peer-reviewed c
A Facile Preparation of Lithium Selenocarboxylates (1993)

Abstract A series of lithium selenocarboxylates 2 were synthesized in good yields by the direct reaction of acyl chlorides with lithium selenide. The salts 2 were soluble in ether and tetrahydrofuran and readily reacted with alkyl iodides to give the corresponding Se-alkyl esters in quantitative yields.
Effects of conjugated linoleic acid levels and feeding intervals on performance, carcass traits and fatty acid composition of finishing barrows (2004)

Two experiments were conducted to investigate the effects of dietary conjugated linoleic acid (CLA) on performance, carcass traits, fatty acid composition and subcutaneous adipose tissue cellularity in finishing barrows. In Experiment 1, 54 crossbred barrows were allotted to one of three treatments, with six pens per treatment and three barrows in each pen. The pigs were fed a diet containing 0, 2, or 4% CLA oil for 6 weeks. Daily gain (P < 0.01) and feed efficiency (P < 0.01) improved with dietary CLA. Loin muscle area (P = 0.01) and intramuscular fat (P = 0.01) increased while 10th rib fat (P = 0.03) and last rib fat (P = 0.02) thickness decreased with increasing dietary CLA. Total CLA isomers increased (P < 0.01) with increasing dietary CLA. Myristic, palmitic and stearic acid levels were increased while oleic, linoleic, linolenic and arachidonic acid decreased in loin muscle and subcutaneous adipose tissue. In Experiment 2, barrows (n = 54) were allotted to one of two treatments with nine pens per treatment and three pigs in each pen. Pigs were fed a diet supplemented with 4% CLA for 3 or 6 weeks before slaughter. Over the entire experimental period, daily gain and feed efficiency were higher (P < 0.01) when CLA was fed for a longer period. Loin muscle area (P < 0.01) and intramuscular fat (P < 0.01) increased while backfat thickness at the 10th (P = 0.03) and last rib (P = 0.04) decreased when CLA was fed for 6 vs. 3 weeks. The number of cells in subcutaneous adipose tissue was not affected while adipocyte volume decreased (P = 0.01) with longer feeding time on dietary CLA. The increased CLA content of pork from CLA fed pigs provides the pork industry with an opportunity to provide value-added, healthful meat products for human consumption with respect to CLA intake and potential improvements in human health.
A Cluster of Hepatitis A Infections Presumed to be Related to Asari Clams and Investigation of the Spread of Viral Contamination from Asari Clams (2018)

In a cluster of hepatitis A infections that occurred in Nagano Prefecture in 2017, hepatitis A virus (HAV) was detected in asari clams (reference food) and the patients' fecal samples. Initially, the asari clams were suspected to be the infection source. However, the exact infection route remained unknown because a patient who had not consumed an asari clam dish also developed the disease. Suspecting a secondary infection originating from the asari clams, we investigated the presence of HAV genomes in water used for washing and soaking the frozen asari clams and detected HAV in the soaking water. These results suggest that soaking water is a risk factor for secondary contamination because of the leakage of HAV accumulated in midgut gland of the asari clam. During the asari clam sand removal process, the water used to clean asari clams spread across a wide area in a concentric fashion, raising concerns that this process may aggravate contamination. In addition to HAV, diarrhea viruses, such as norovirus, have often been detected in bivalves, including asari clams. Thus, handling these foodstuffs requires adequate care.
Intermolecular Potential Function for the Physical Adsorption of Rare Gases in Silicalite (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIntermolecular Potential Function for the Physical Adsorption of Rare Gases in SilicaliteRoland J-M. Pellenq and David NicholsonCite this: J. Phys. Chem. 1994, 98, 50, 13339–13349Publication Date (Print):December 1, 1994Publication History Published online1 May 2002Published inissue 1 December 1994https://pubs.acs.org/doi/10.1021/j100101a039https://doi.org/10.1021/j100101a039research-articleACS PublicationsRequest reuse permissionsArticle Views508Altmetric-Citations129LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Complete Genome Sequence of Weissella cibaria Strain BM2, Isolated from Korean Kimchi (2020)

<i>Weissella cibaria</i> appears to have broad-spectrum health benefits. Here, we report the genome sequence of <i>Weissella cibaria</i> strain BM2, which was isolated from homemade kimchi; it consists of one circular chromosome of 2,462,443 bp and one plasmid of 11,067 bp. A total of 2,337 coding sequences were predicted, including 2,117 protein-coding sequences and a G+C content of 45.06%.
Geometrical analysis of precessional switching (2004)

In this paper we present a magnetization switching in magnetic particles and films. It is one of the fundamental issues in spin dynamics studies due to its relevance in magnetic recording and data storage technology. In this area it has been recently recognized the potential convenience of realizing the switching of magnetization in particles and film by means of precessional motion of magnetization. In the typical precessional switching process the magnetization is initially along the easy axis of the body and the external magnetic field is approximately orthogonal to the easy axis. If the field is strong enough and applied for a sufficiently long time, the magnetization can be reversed. We will study this process by using the Landau-Lifshitz-Gilbert (LLG) equation.
Comparative Toxicological Study of the Novel Protein Phosphatase Inhibitor 19-Epi-Okadaic Acid in Primary Cultures of Rat Cerebellar Cells (2013)

Okadaic acid (OKA) and analogues are frequent contaminants of coastal waters and seafood. Structure analysis of the isolated OKA analogue 19-epi-OKA showed important conformation differences expected to result in lower protein phosphatase (PP) inhibitory potencies than OKA. However, 19-epi-OKA and OKA inhibitory activities versus PP2A were unexpectedly found to be virtually equipotent. To investigate the toxicological relevance of these findings, we tested the effects of 19-epi-OKA on cultured cerebellar cells and compared them with those of OKA and its isomer dinophysistoxin-2. 19-epi-OKA caused degeneration of neurites and neuronal death with much lower potency than its congeners. The concentration of 19-epi-OKA that reduced after 24h the maximum neuronal survival (EC5024) by 50% was ~300nM compared with ~2nM and ~8nM for OKA and dinophysistoxin-2, respectively. Exposure to 19-epi-OKA resulted also in less toxicity for cultured glial cells (EC5024,19-epi-OKA ~ 600nM; EC5024,OKA ~ 20nM). 19-epi-OKA induced apoptotic condensation and fragmentation of chromatin, activation of caspases, and activation of ERK1/2 MAP kinases, features previously reported for OKA and dinophysistoxin-2. Also, differential sensitivity to 19-epi-OKA was observed between neuronal and glial cells, a specific characteristic shared by OKA and dinophysistoxin-2 but not by other toxins. Our results are consistent with 19-epi-OKA being included among the group of toxins of OKA and derivatives and support the suitability of cellular bioassays for the detection of these compounds.
Properties of -Glucosidase Purified from Clostridium thermocellum (1982)

A cell-bound β-glucosidase (β-d-glucoside glucohydrolase; EC 3.2.1.21) from Clostridium thermocellum was purified to apparent homogeneity. A molecular weight of about 43000 gel fluration of the native enzyme on Ultrogel AcA34. A constant ratio of aryl-β-glucosidase and cellcouse throughout purification, similar heat stabilities, pH profiles and sensitivity to different hiibitor and competitive inhibition of the aryl-β-gluosidase and the β suggest that the same enzyme accounts for the aryl-β-glucosidase and the cellobiase activities. However, the affinity for cellobiose was very much lower than for p-β-d-glucoside. The β-glucosidase had maximum rates at pH 6·0 to 6·5 for both activities. The enzyme was specific for substrates with the both activities. β-configuration. particulary and β-1,3 and β-1,2 linkages. The enzyme did not hydrolyse carboxymethylcellulose or cellulose, but hydrolysed cello-oligosaccharides. It was strongly inhibited by d-glucono-δ-lactone was sensitive to thiol reagents. When preparations of C. thermocellm cellulase were supplemented with purified β-glucosidase, glucose was the predominant product of cellulose and the rate of saccharification was increased.
Comparison of liver function and safety in hepatocellular cancer patients treated with DEB-TACE and cTACE: a multi-center, retrospective cohort study (2019)

Background: This study aimed to compare the live function change and adverse events (AEs) between drug-eluting beads (DEB) transarterial chemoembolization (TACE) with CalliSpheres ® microspheres (CSM) and conventional TACE (cTACE) in treating hepatocellular carcinoma (HCC) patients.
 Methods: Three hundred and thirty-five HCC patients underwent DEB-TACE with CSM (n=171, DEB-TACE group) or cTACE (n=164, cTACE group) were consecutively enrolled in this multi-center, retrospective cohort study. Liver function indexes were reviewed before treatment (W0), at 1 week (W1) and 1 month (M1) post treatment. Moreover, AEs during operation and hospitalization were retrieved as well.
 Results: The changes of albumin (ALB) [–3.55 (–6.25 to –0.43) vs. –2.20 (–4.63–0.00), P=0.043] and total protein (TP) [–4.62 (–10.18–0.43) vs. –2.50 (–7.08–1.08), P=0.013] from W1 to W0 were lower in DEB-TACE group compared to cTACE group, while no difference was observed referring to the change of alanine aminotransferase (ALT) (P=0.494), aspartate aminotransferase (AST) (P=0.747), alkaline phosphatase (ALP) (P=0.895), total bilirubin (TBIL) (P=0.059), total bile acid (TBA) (P=0.491) from W1 to W0. And the changes of these seven indexes from M1 to W0 were all similar between DEB-TACE group and cTACE group (all P>0.05). Besides, the occurrence of pain during treatment (19.3% vs. 11.0%, P=0.034) and the occurrence of fever during hospitalization (18.1% vs. 9.1%, P=0.017) were both increased in DEB-TACE group compared to cTACE group.
 Conclusions: DEB-TACE with CSM is non-inferior to cTACE in terms of liver function change, while DEB-TACE with CSM leads to higher incidences of pain and fever.
A 10 Mb/s hybrid two-point modulator with front-end phase selection and dual-path DCO modulation (2015)

This paper presents a hybrid two-point modulator for high data rate modulation. The two-point modulator utilizes a phase selection circuit with a high-frequency ΔΣ modulator (DSM) in low-pass modulation to achieve fine resolution for delay mismatch calibration. For high-pass modulation, a separate multi-bit path is designed for a digitally-controlled oscillator (DCO) in addition to the loop control path. A finite impulse response (FIR) filter is introduced in the high-pass modulation path to suppress quantization noise, while offering time-interleaving operation to mitigate the DCO sensitivity for each switching time. The proposed modulator is implemented in 65nm CMOS. Experimental results show that the modulator can achieve 10Mb/s GFSK modulation with the fine time resolution of 138ps.
Admission rapid thrombelastography predicts development of pulmonary embolism in trauma patients (2012)

Prognostic study, level III.
Understanding the Virus Threat and Developing Effective Anti-Virus Policy (2003)

According to recent ICSA statistics, your company was over 99% likely to be confronted with the threat of a virus infection in the year 2000, over 50% of which could be classified as a virus disaster. Was your company prepared to deal with this threat? This paper focuses on providing the reader with an overview of the current virus landscape and aids in developing best practice anti-virus policies. After presenting the threat, we’ll introduce you to today’s most popular anti-virus tools. Using your knowledge of the threat and of the solutions will help you manage the risk of infection, ensuring confidentiality, integrity, and availability of computer systems and data and minimize the cost of reactive manag ment in case your proactive measures fail.
La poética de la vanguardia: el silencio y el ruido en el devenir del verso libre (2010)

Tesis doctoral inedita, leida en la Universidad Autonoma de Madrid, Facultd de Filosofia y Letras, Departamento de Filologia Espanola. Fecha de lectura: 11 de junio de 2010
Design of a general clinical notification system based on the publish-subscribe paradigm. (1997)

We describe the design and initial implementation of a notification sub-system, as a component of a modern information management architecture. The system, based on the publish-subscribe paradigm, provides a framework of event-based communications for the implementation of various important clinical applications including the notification of alerts and reminders with escalation algorithms, the reliable distribution of documents, and the implementation of intelligent patient-specific monitoring processes. The initial implementation of the system, providing the notification of the unit staff about new orders, indicates that the model is viable both in terms of functionality and ability to scale up.
Carbon Fiber-Based Grid Array Interconnects (2007)

This paper presents a new type of grid array electrical interconnect that uses carbon fiber as the conductive medium. Characterization of the electrical properties suggest that carbon fiber-based interconnects can be applied across different packaging levels, such as semiconductor die to substrate, integrated circuit package-to-board and board-to-board interconnections. Multiple interconnect contacts have been integrated to provide multiple interconnections within a single assembly. Each interconnect contact consists of a large number of carbon fibers which can act cooperatively to provide a high degree of reliability and predictability to the interconnect function. An optional metal coating, such as nickel, copper, aluminum or gold, can be applied over the carbon fibers to enhance conductivity and solderability. These novel interconnects can be joined to conventional circuitry by several techniques including pressure/physical contact, solder, and conductive adhesives (U.S. Patent 007 220 131).
DNA exchange and insertional inactivation in spirochetes. (2000)

Spirochetes have complex life cycles and are associated with a number of diseases in humans and animals. Despite their significance as pathogens, spirochete genetics are in their early stages. However, gene inactivation has been achieved in Borrelia burgdorferi, Brachyspira hyodysenteriae, and Treponema denticola. Here, we review methods that have been used in spirochetes for gene inactivation and DNA exchange, with a primary focus on B. burgdorferi. We also describe factors influencing electrotransformation in B. burgdorferi. In summary, optimal transformation frequencies are obtained with log phase bacteria, large amounts of DNA (up to 50 microg per transformation), and high field strength (12.5-37.5 kV/cm). Infectious B. burgdorferi isolates transform with frequencies 100-fold lower than those found for high passage, non-infectious strains. Surface characteristics of the bacteria, which often correlate with infectivity, are among the obstacles to effective transformation by electroporation.
Distance distributions in proteins recovered by using frequency-domain fluorometry. Applications to troponin I and its complex with troponin C (1988)

We used resonance energy transfer to examine the distribution of distances between two sites on troponin I (TnI). The donor (D) was the single tryptophan residue at site 158 (Trp 158), and the acceptor (A) was cysteine 133 (Cys 133) which was labeled with N-(iodoacetyl)-N'-(1-sulfo-5-naphthyl)ethylenediamine (IE). A distribution of D-A distances results in a distribution of donor decay times, which were resolved by using frequency-domain fluorometry. In the native state we recovered a relatively narrow distribution of D-A distances. The widths of the distance distributions were found to increase progressively and dramatically with increasing concentrations of guanidine hydrochloride. Binding of calcium-free troponin C (TnC) to troponin I did not alter the distance distribution. Addition of Ca2+ to the TnI.TnC complex resulted in a sharper distance distribution and protected against the guanidine hydrochloride induced increase in the width of the distance distribution. Additionally, the same distance distributions were recovered for native and denatured TnI when the Forster distance for energy transfer was decreased by acrylamide quenching. These results demonstrate that distance distributions can be recovered with good accuracy, to the extent of revealing modest changes due to binding of other components. This technique should have widespread applications in studies of protein folding.
Effects of Cutting Direction, Rake Angle, and Depth of Cut on Cutting Forces and Surface Quality during Machining of Balsam Fir (2013)

Effects of cutting direction with respect to grain angle, rake angle, and depth of cut on cutting forces and surface quality during machining of balsam fir were evaluated. These factors were analyzed within a perspective of their application to a chipper-canter machining process. Balsam fir is one of the most important boreal species in Canada and is widely used in the pulp and paper industry and construction applications. Wood samples prepared at four cutting directions (0-90°, 15-75°, 30-60°, and 45-45°) were machined using four rake angles (35, 45, 55, and 65°) and three cutting depths (1, 2, and 3 mm). Results showed that rake angle was the most important factor affecting cutting forces and surface quality. Furthermore, as rake angle increased, the effect of cutting direction and depth of cut on cutting forces and surface quality became less important. At 65° rake angle, cutting forces decreased and surface quality increased as depth of cut passed from 3 to 1 mm. Surface quality also improved as cutting action changed from the 0-90° to 45-45° direction. The results gave useful information for improving the performance of the chipper-canter in terms of surface quality and energy consumption.
The leakage current improvement in an ultrashallow junction NMOS with Co silicided source and drain (2000)

The leakage current characteristics of the cobalt silicided NMOS transistors with a junction depth of 800 /spl Aring/ have been studied. In order to minimize the junction leakage current, the thickness of the CoSi/sub 2/ layer should he controlled under 300 /spl Aring/ and the Si surface damage induced by the gate spacer etch should be minimized. The post furnace annealing after the second silicidation by the rapid thermal annealing (RTA) process also affected the leakage current characteristics. The gate induced drain leakage (GIDL) current was not affected by the lateral encroachment of CoSi/sub 2/ layer into the channel direction when the gate spacer length was larger than 400 /spl Aring/.