gebhart/patrepeval huggingface dataset:
Interspecific hybridization, polyploidization and backcross of Brassica oleracea var. alboglabra with B. rapa var. purpurea morphologically recapitulate the evolution of Brassica vegetables (2016)

Brassica oleracea and B. rapa are two important vegetable crops. Both are composed of dozens of subspecies encompassing hundreds of varieties and cultivars. Synthetic B. napus with these two plants has been used extensively as a research model for the investigation of allopolyploid evolution. However, the mechanism underlying the explosive evolution of hundreds of varieties of B. oleracea and B. rapa within a short period is poorly understood. In the present study, interspecific hybridization between B. oleracea var. alboglabra and B. rapa var. purpurea was performed. The backcross progeny displayed extensive morphological variation, including some individuals that phenocopied subspecies other than their progenitors. Numerous interesting novel phenotypes and mutants were identified among the backcross progeny. The chromosomal recombination between the A and C genomes and the chromosomal asymmetric segregation were revealed using Simple Sequence Repeats (SSR) markers. These findings provide direct evidence in support of the hypothesis that interspecific hybridization and backcrossing have played roles in the evolution of the vast variety of vegetables among these species and suggest that combination of interspecific hybridization and backcrossing may facilitate the development of new mutants and novel phenotypes for both basic research and the breeding of new vegetable crops.
Feature selection for classification: A review (2014)

However, these collected data are usually associated with a high level of noise. There are many
reasons causing noise in these data, among which imperfection in the technologies that collected
the data and the source of the data itself are two major reasons. For example, in the medical images
domain, any deficiency in the imaging device will be reflected as noise for the later process. This
kind of noise is caused by the device itself. The development of social media changes the role of
online users from traditional content consumers to both content creators and consumers. The quality
of social media data varies from excellent data to spam or abuse content by nature. Meanwhile,
social media data are usually informallywritten and suffers from grammaticalmistakes, misspelling,
and improper punctuation. Undoubtedly, extracting useful knowledge and patterns from such huge
and noisy data is a challenging task.
European Union Law (2011)

Pt 1: The European Union - Emergence of New Paths Towards Integration The Community Integration Path The Non-Community Integration Path Bringing Together the Paths pf Integration into One European Union Towards a Constitution for Europe Pt 2: Jurisdiction of the European Union Substantive Scope of the Community Treaties Substantive Scope of Titles V and VI of the EU Treaty Temporal Scope of the Treaties Territorial Scope of the Treaties Exceptions to the Application of the Treaties Pt 3: The Actors of the European Union The Institutions and Bodies of the Union The Member States of the Union The Citizens of the Union The Relationship Between the Actors Pt 4: The Decision-Making Process Within the European Union Community Decision-Making Non-Community Decision-Making Legitimacy of Decision-Making Pt 5: Sources of Law of the European Union Community Law Non-Community Acts of the Union Pt 6: The European Union in International Legal Transactions The Position in International Law of th
Texture-Based Modeling of Sheet Metal Forming and Springback (2009)

In this paper the application of a crystal plasticity model for body-centered cubic crystals in the simulation of a sheet metal forming process is discussed. The material model parameters are identified by a combination of a texture approximation procedure and a conventional parameter identification scheme. In the application of a cup drawing process the model shows an improvement of the strain and earing prediction as well as the qualitative springback results in comparison with a conventional phenomenological model. 1
Association of human telomerase reverse transcriptase gene polymorphisms, serum levels, and telomere length with renal cell carcinoma risk and pathology (2015)

Human telomerase reverse transcriptase (hTERT) is the catalytic subunit of the human telomerase and plays a key role in telomere restitution and gene regulation. Evidence suggests that hTERT is linked with the risk and progression of several malignancies, but there are no comprehensive data in renal cell carcinoma (RCC). In this case-control study, we assessed seven polymorphic hTERT gene variants (MNS16A, rs2736100, rs2736098, rs7726159, rs2853677, rs13172201, and rs10069690), hTERT serum levels, and the telomere length of 663 individuals, including 243 with clear cell RCC and 420 age- and gender-matched healthy controls. The SL and SS genotypes of MNS16A were associated with a decreased risk for RCC on the multivariable logistic regression analysis (SL-OR 0.72, SS-OR 0.37, P < 0.001). The GG genotype of rs2736098 was associated with a decreased risk for RCC compared with AA (OR 0.18, P < 0.001). Both telomere length and hTERT serum levels increased with every G allele in rs2736098 (P = 0.008). Pretherapeutic hTERT serum levels were higher in patients with advanced tumor stages (P = 0.037) and distant metastases (P = 0.006). Rs2736100, rs7726159, rs2853677, rs13172201, and rs10069690 were not linked with RCC risk, and none of the polymorphisms was associated with RCC pathology. In conclusion, the polymorphic number of tandem repeats in hTERT (MNS16A) and rs2736098 may be linked with the risk for RCC. Rs2736098 may have an important role in telomere length restitution and serum hTERT levels may represent a novel biomarker for RCC. © 2015 Wiley Periodicals, Inc.
Compact Trench Floating Field Rings Termination for 10kV+ Rated SiC n-IGBTs (2022)

This work presents the design methodology and performance of a compact edge termination structure aiming 10kV+ rated Silicon Carbide (SiC) devices. Standard Floating Field Rings (FFRs) for such high voltage rating SiC devices are not favored because they are inefficient in terms of the achievable breakdown voltage as a percentage of the 1D maximum, consume large chip area, require high implantation energies and small gaps between rings which can violate fabrication limits. We show that the implantation of Aluminium at the bottom of carefully positioned trenches can be analogous to deep Aluminium implantation in terms of performance, thus annulling the need for small gaps between rings and MeV ion implantation. We optimize the distribution of trenches by placing them in multiple zones of different expansion coefficient. The proposed multi expansion ratio Trench FFR termination was utilized to terminate the active area of a 10kV rated Punch Through n-IGBT having 0.8 μm p-body and 100 μm, 3×10 14 cm -3 drift region. We found the 0.6–0.8 µm to be the most optimum trench depth, achieving over 10 kV within less than 500 μm of termination length.
Magneto-optical effects with cold lithium atoms (2001)

We report measurements of magneto-rotational effects in the coherent forward scattering of light on an ensemble of cold 7Li atoms. The effect of the cold atomic cloud on the polarization state of a probe beam is studied for magnetic fields in the Faraday and Voigt configurations. Magneto-optical effects with cold atoms have the potential to be highly sensitive tools for the spatially and temporally resolved detection of either small atomic ensembles or small magnetic fields
Transmembrane 4 superfamily protein CD151 (PETA-3) associates with beta 1 and alpha IIb beta 3 integrins in haemopoietic cell lines and modulates cell-cell adhesion. (1999)

CD151 (PETA-3/SFA-1) is a member of the transmembrane 4 superfamily (TM4SF) of cell-surface proteins and is expressed abundantly both on the cell surface and in intracellular membranes by the haemopoietic cell lines M07e, HEL and K562. In the presence of mild detergent (CHAPS), CD151 co-immunoprecipitated with integrin alpha 4 beta 1, alpha 5 beta 1, alpha 6 beta 1 and alpha IIb beta 3. The association of CD151 with alpha 4 beta 1 and alpha 5 beta 1 seemed to be constitutive, as it was not modified by treatment of M07e cells with cytokines that regulate integrin function by 'inside-out' signalling. CD151 also associated with other tetraspans in an apparently cell-type-specific fashion, as defined by its co-precipitation with CD9, CD63 and CD81 from M07e cells, but not from K562 cells, which express similar levels of these proteins. F(ab')2 fragments of monoclonal antibodies (mAbs) against CD151 caused homotypic adhesion of HEL and K562 cells that was dependent on energy and cytoskeletal integrity and was augmented in the presence of RGDS peptides. The adhesion was not blocked by function-inhibiting mAbs against beta 1 or beta 3 integrins, suggesting that cell-cell adhesion was not mediated by the binding of integrin to a cell-associated ligand. Furthermore, mAb CD151 did not affect adhesion of the cells to fibronectin, laminin, collagen or fibrinogen, which are ligands for alpha 4 beta 1, alpha 5 beta 1, alpha 6 beta 1 and alpha IIb beta 3 integrins. Taken together, these results indicate that the ligation of CD151 does not induce the up-regulation of integrin avidity, but might act as a component of integrin signalling complexes.
studio pri Dikinolio (2-a raporto) (1937)

Studo pri Dikinolilo (2-a raporto)
Time to Achieving Clinically Significant Outcomes After Meniscal Allograft Transplantation (2022)

This study suggests that the majority of patients have clinically significant improvements in pain and function after MAT, with more than 50% of patients experiencing clinically significant improvement within the first postoperative year. Workers' compensation status and high BMI may prolong time to achievement of MCID and PASS after MAT.
Review of optical direct-write technology for semiconductor manufacturing (2023)

Optical direct-write technology has been studied since the successful development of the micromirror-based spatial light modulators in the 1990s. It is expected to have advantages over electron beam direct-write in the viewpoints of higher productivity and common resist process with existing semiconductor manufacturing. In the 2000s, there was an effort to develop an optical direct-write system using deep ultraviolet (DUV) excimer laser and grayscale tilt micromirror devices, aiming at low-volume manufacturing of semiconductor devices. Recently, a new scheme of optical direct-write, called the digital scanner, has been demonstrated. It uses solid-state DUV laser and digitally controlled spatial light modulator. Past development activity of optical direct-write is reviewed with discussion of the merits and demerits of the proposed technological options in the new system, comparing them to past efforts.
The Impact of Off-spec Conditions on the Performance of a PEM Fuel Cell (2009)

--
Abstract TMP2: Intravenous Thrombolysis For Ischemic Stroke With Unknown Time Of Onset: Differences Between Wake-up Stroke And Non-wake-up Subtypes: EOS (2023)

Background: The unknown onset stroke can be categorized into two groups; wake-up stroke (WUS) and non-wake-up unwitnessed stroke with a time of onset unavailable due to aphasia, impaired consciousness, or cognitive impairment (non-wake-up unknown onset stroke, non-WUS). We aimed to assess the differences in efficacy and safety of intravenous thrombolysis (IVT) for these subgroups. Methods: Patients with an unknown onset stroke from the Evaluation of unknown Onset Stroke thrombolysis trials (EOS) collaboration were evaluated using an individual patient-level database of randomized controlled trials comparing IVT with placebo/standard treatment. A favorable outcome was defined as a modified Rankin Scale score 0-1 at 90 days. Safety outcomes included symptomatic intracranial hemorrhage (sICH) at 22-36 hours and 90-day mortality. The effect of IVT was compared between the treatment groups in the WUS and non-WUS with mixed-effect logistic-regression analysis. Results: A total of 634 patients (233 women [36.8%], median age 70 years [IQR 61-76]) were analyzed. In patients with non-WUS (n=92 [14%]), advanced age, atrial fibrillation, vessel occlusion on MRA and high NIHSS score were more prevalent (P&lt;0.01 for each) than those with WUS (n=542 [86%]). Overall, no significant interaction was noted between the mode of onset and treatment effect (Pinteraction=0.782). In patients with WUS, a favorable outcome was more common in the IVT group than the control (149 [54.8%] vs. 117 [45.5%], adjusted OR: 1.45, 95% CI 1.01-2.11), death occurred in 11 [4.0%] and 5 [1.9%] (p=0.099), and sICH occurred in 5 [1.8%] and 1 [0.3%] (p=0.142). In patients with non-WUS, no significant difference was observed for a favorable outcome (16 [37.2%] vs. 14 [29.2%], aOR 1.73 [0.60-4.98]). One death and one sICH were reported in the IVT group, but none in the controls. Conclusions: The benefit of IVT was significant in patients with WUS. Excellent outcome was also numerically more prevalent in non-WUS but this did not reach significance, probably due to the lack of statistical power.
Quantitation of Ivosidenib, A Novel Mutant IDH1 Inhibitoron Mice DBS: Application to a Pharmacokinetic Study (2019)

Ivosidenib is an approved drug for relapsed or refractory IDH1 mutant AML patients. The goal of the present work is to develop and validate an LC-MS/MS method for the quantitation of ivosidenib in mice dried blood spots (DBS) as per regulatory guideline in the linearity range of 1.10-3293 ng/mL. To date there is no bioanalytical method reported for quantitation of ivosidenib. The chromatographic resolution of ivosidenib and internal standard (warfarin) was achieved on a C<sub>18</sub> column with an isocratic mobile phase. All validation parameters met the acceptance criteria. The intra- and inter-day precision was in the range of 2.79-10.5 and 5.76-9.02%, respectively. Ivosidenib was stable for 3 freeze/thaw cycles, up to 7 days at room temperature and for one month at -80°C. The applicability of the validated method is shown in a mice pharmacokinetic study. Ivosidenib was quantifiable up to 24 and 36 h following intravenous and oral administration to mice, respectively. The oral bioavailability was 48%. Comparison of DBS vs. plasma concentrations of ivosidenib showed excellent correlation, indicating DBS can be used as an alternative for plasma for pharmacokinetic analysis.
Titanium Superoxide Catalyzed Oxidative Esterification of Aldehydes (2016)

Key words titanium superoxide - heterogeneous catalysis - esterification - oxidation - aldehydes - arenes
Heterogeneous SAR head distribution model for correlation demonstration to ears canal acoustic neuroma pathology (2015)

Abundant applications of wireless devices raise growing health concerns among public users. Efforts to display definite relation between human exposure to wireless RF radiation and health diseases' appearance are not yet conclusive. Causal relationship and defined correlations are yet to be demonstrated. Case study of Acoustic Neuroma ear's pathology is estimated with respect to SAR distribution at typical physical appearances. In this paper, homogeneous and heterogeneous models are employed for SAR evaluation at Acoustic Neuroma region, yielding values of 1.4 Watt/Kg and 0.4 Watt/Kg, respectively. Though values are below known limits, heat absorption could initiate some of this disease eruption.
CaSCADE: Compressed Carrier and DOA Estimation (2016)

Spectrum sensing and direction of arrival (DOA) estimation have been thoroughly investigated, both separately and as a joint task. Estimating the support of a set of signals and their DOAs is crucial to many signal processing applications, such as Cognitive Radio (CR). A challenging scenario, faced by CRs, is that of multiband signals, composed of several narrowband transmissions spread over a wide spectrum each with unknown carrier frequencies and DOAs. The Nyquist rate of such signals is high and constitutes a bottleneck both in the analog and digital domains. To alleviate the sampling rate issue, several sub-Nyquist sampling methods, such as multicoset sampling or the modulated wideband converter (MWC), have been proposed in the context of spectrum sensing. In this work, we first suggest an alternative sub-Nyquist sampling and signal reconstruction method to the MWC, based on a uniform linear array (ULA). We then extend our approach to joint spectrum sensing and DOA estimation and propose the CompreSsed CArrier and DOA Estimation (CaSCADE) system, composed of an L-shaped array with two ULAs. In both cases, we derive perfect recovery conditions of the signal parameters (carrier frequencies and DOAs if relevant) and the signal itself and provide two reconstruction algorithms, one based on the ESPRIT method and the second on compressed sensing techniques. Both our joint carriers and DOAs recovery algorithms overcome the well-known pairing issue between the two parameters. Simulations demonstrate that our alternative spectrum sensing system outperforms the MWC in terms of recovery error and design complexity and show joint carrier frequencies and DOAs from our CaSCADE system's sub-Nyquist samples.
Pipeline gas from lignite gasification: current commercial economics (1969)

This report updates the commercial economics of the production of pipeline gas from lignite, incorporating the results of the experimental program into the proposed commercial design, and using current costs for material and labor, the two design cases in this study consider a straightforward commercial approach - that is, lignite, water, and air are processed to produce one major saleable product, pipeline gas, at a rate of 250 billion Btu/day. The pipeline gas produced meets or exceeds the specifications adopted by all OCR contractors in June 1965. The cold-gas thermal efficiency of this plant is 62.5% at 150 psi and 59.2% at 300 psi. The twenty-year average price of pipeline gas from this plant at two pressure levels is shown as a function of lignite cost. Costs are calculated using the AGA accounting procedure adopted by OCR in June 1965. At the 150 psi level, lignite at 8 cents/MM Btu results in a pipeline gas price of 38.1 cents/MM Btu; the corresponding gas price for 11 cents/MM Btu lignite is 43.1 cents/MM Btu. At the 300 psi level, gas prices are from 1.2 to 1.5 cents/MM Btu higher.
Direct overwrite without initialization in a bilayer magneto-optical disk (1990)

We propose and analyze a bilayer direct overwrite scheme that does not require an initialization bias field. This is achieved by using permanent domains in a reference layer to help stabilize bits in a memory layer on writing, and to destabilize the memory layer bits on erasure.
Multi-trigger resist patterning with ASML NXE3300 EUV scanner (2018)

Irresistible Materials (IM) is developing novel resist systems based on the multi-trigger concept, which incorporates a dose dependent quenching-like behaviour. The Multi Trigger Resist (MTR) is a negative tone crosslinking resist that does not need a post exposure bake (PEB), and during the past years, has been mainly tested using interference lithography at PSI. In this study, we present the results that have been obtained using MTR resists, performing EUV exposures on ASML NXE3300B EUV scanner at IMEC. We present the lithography performance of the MTR1 resist series in two formulations – a high-speed baseline, and a formulation designed to enhance the multi-trigger behaviour. Additionally, we present results for the MTR2 resist series, which has been designed for lower line edge roughness. The high-speed baseline resist (MTR1), showed 18 nm resolution at 20mJ/cm<sup>2</sup>. The MTR2 resist shows 16nm half pitch lines patterned with a dose of 38mJ/cm<sup>2</sup>, giving a LER of 3.7 nm. Performance across multiple process conditions are discussed. We performed etch rate measurement and the multi-trigger resist showed etch resistance equivalent or better than standard chemically amplified resist. This could compensate for the lower film thickness required to avoid pattern collapse at pitch 32nm.
Comparison of transonic wind tunnel and flight data for a high performance fighter aircraft (1992)

An existing data set for a 4.7% F-15 aircraft model taken in the 4 x 4-fOOt Polysonic Wind Tunnel was corrected to full scale at 30,000 feet and compared to flight test data. It is concluded that with proper wind tunnel boundary interference corrections, good instrumentation, and meticulous operational procedures, small economical wind tunnels can produce baseline quality data for fighter aircraft.
LysK CHAP endopeptidase domain is required for lysis of live staphylococcal cells (2009)

LysK is a staphylococcal bacteriophage endolysin composed of three domains: an N-terminal cysteine, histidine-dependent amidohydrolases/peptidases (CHAP) endopeptidase domain, a midprotein amidase 2 domain, and a C-terminal SH3b_5 (SH3b) cell wall-binding domain. Both catalytic domains are active on purified peptidoglycan by positive-ion electrospray ionization MS. The cut sites are identical to LytA (phi11 endolysin), with cleavage between d-alanine of the stem peptide and glycine of the cross-bridge peptide, and N-acetylmuramoyl-l-alanine amidase activity. Truncations of the LysK containing just the CHAP domain lyse Staphylococcus aureus cells in zymogram analysis, plate lysis, and turbidity reduction assays but have no detectable activity in a minimal inhibitory concentration (MIC) assay. In contrast, truncations harboring just the amidase lytic domain show faint activity in both the zymogram and turbidity reduction assays, but no detectable activity in either plate lysis or MIC assays. A fusion of the CHAP domain to the SH3b domain has near full-length LysK lytic activity, suggesting the need for a C-terminal binding domain. Both LysK and the CHAP-SH3b fusion were shown to lyse untreated S. aureus and the coagulase-negative strains. In the checkerboard assay, the CHAP-SH3b fusion achieves the same level of antimicrobial synergy with lysostaphin as the full-length LysK.
Metal ion coordinating properties of pyrimidine-nucleoside 5'-monophosphates (CMP, UMP, TMP) and of simple phosphate monoesters, including D-ribose 5'-monophosphate. Establishment of relations between complex stability and phosphate basicity (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMetal ion coordinating properties of pyrimidine-nucleoside 5'-monophosphates (CMP, UMP, TMP) and of simple phosphate monoesters, including D-ribose 5'-monophosphate. Establishment of relations between complex stability and phosphate basicitySalah S. Massoud and Helmut SigelCite this: Inorg. Chem. 1988, 27, 8, 1447–1453Publication Date (Print):April 1, 1988Publication History Published online1 May 2002Published inissue 1 April 1988https://pubs.acs.org/doi/10.1021/ic00281a030https://doi.org/10.1021/ic00281a030research-articleACS PublicationsRequest reuse permissionsArticle Views451Altmetric-Citations163LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts