gebhart/patrepeval huggingface dataset:
An XmnI RFLP detected with a cDNA probe for theCYP2Cgene locus on chromosome 10 (1989)

Journal Article An XmnI RFLP detected with a cDNA probe for the CYP2C gene locus on chromosome 10 Get access A.C. Gough, A.C. Gough Imperial Cancer Research Fund, Human Genetic Resources Laboratory, Clare Hall LaboratoriesBlanche Lane, South Mimms, Herts EN6 3LD Search for other works by this author on: Oxford Academic PubMed Google Scholar N.K. Spurr, N.K. Spurr Imperial Cancer Research Fund, Human Genetic Resources Laboratory, Clare Hall LaboratoriesBlanche Lane, South Mimms, Herts EN6 3LD Search for other works by this author on: Oxford Academic PubMed Google Scholar R.R. Meehan, R.R. Meehan 1Imperial Cancer Research Fund, Laboratory of Molecular Pharmacology and Drug Metabolism, University Department of BiochemistryHugh Robson Building, George Square, Edingburgh EH8 9XD, UK Search for other works by this author on: Oxford Academic PubMed Google Scholar J.S. Miles, J.S. Miles 1Imperial Cancer Research Fund, Laboratory of Molecular Pharmacology and Drug Metabolism, University Department of BiochemistryHugh Robson Building, George Square, Edingburgh EH8 9XD, UK Search for other works by this author on: Oxford Academic PubMed Google Scholar C.R. Wolf C.R. Wolf Imperial Cancer Research Fund, Human Genetic Resources Laboratory, Clare Hall LaboratoriesBlanche Lane, South Mimms, Herts EN6 3LD Search for other works by this author on: Oxford Academic PubMed Google Scholar Nucleic Acids Research, Volume 17, Issue 11, 12 June 1989, Page 4426, https://doi.org/10.1093/nar/17.11.4426 Published: 12 June 1989
Microgravity culture condition reduces immunogenicity and improves function of pancreatic islets1 (2002)

Microgravity condition decreases immunogenicity and significantly improves the function of secretory cells.
Role of Excision Repair in UVB-Induced Depletion and Recovery of Human Epidermal Langerhans Cells (1992)

Skin exposure to UVB radiation deprives the antigen-presenting function and OKT6 monoclonal antibody-binding characteristics of Langerhans cells. Decrease of Langerhans cell population could be relevant to immune surveillance disturbance in the UV-exposed skin. Patients with xeroderma pigmentosum exhibit a thousandfold higher risk for sunlight-induced skin cancers than patients with normal skin, and also have various defects in cellular immunity. Therefore, studies of numerical and structural changes in epidermal Langerhans cells of patients with xeroderma pigmentosum after UVB irradiation compared with normal subjects may contribute to understanding the role of antigen-presenting cells in photocarcinogenesis. The effect of UVB radiation on OKT6+ Langerhans cells was studied in epidermal sheets obtained from irradiated normal subjects (36 and 49 years old) and subjects with xeroderma pigmentosum complementation group A (21 years old), complementation group D (32 years old), and variant (35 and 60 years old). Langerhans cell densities in chronically sunlight-exposed skin were remarkably reduced in patients with xeroderma pigmentosum group A but only slightly in those with xeroderma pigmentosum variant and in normal subjects compared with covered skin. Structural changes were substantial in Langerhans cells of chronically exposed patients with xeroderma pigmentosum group A but fewer in subjects with other xeroderma pigmentosum groups and in normal subjects. A single irradiation of three times the minimal erythema dose induced a large reduction of Langerhans cells from 3 to 7 days in all subjects. However, subsequent reappearance and return to preirradiated levels was delayed more in patients with xeroderma pigmentosum group A than in those with xeroderma pigmentosum variant and normal subjects. These results indicate (1) an essential role for excisional repair in the UVB-induced depletion, recovery, and maintenance of the epidermal Langerhans cell population, and (2) a possible, but not confirmed, relationship between depletion of Langerhans cells and earlier photocarcinogenesis in xeroderma pigmentosum.
Deep learning based denoising of Lu-177 SPECT/CT imaging (2023)

Ziel/Aim CNN-based denoising is increasingly applied to suppress noise in PET images [1]. This work evaluates these methods for application in SPECT imaging based on a previously presented large dataset of 10,000 Monte Carlo (MC) simulated SPECT acquisitions [2].
Temperature-insensitive fiber twist sensor based on elliptical-core few-mode fiber (2016)

A highly sensitive fiber optics twist sensor is proposed and experimentally demonstrated using elliptical-core few-mode fiber (e-FMF). With the help of a fixed-phase plate for conversion from LP<sub>11</sub> to LP<sub>01</sub> mode, the twist angle can be linearly mapped to the spatial rotation of LP<sub>11</sub> mode profile and consequently discriminated by monitoring the optical power variation at the standard single-mode fiber (SSMF) output. When the optical power at the e-FMF output is 10 mW, the twist angle within the range of ±39° can be successfully detected with a sensitivity of more than 20 μW/°. Meanwhile, the twist direction can be identified simultaneously. In particular, when the twist angle ranges from -12.5° to 20.1°, the sensitivity is higher than 100 μW/°. Both temperature-insensitive operation from 20°C to 150°C and e-FMF length insensitive operation are experimentally verified.
Two-way Clustering using Fuzzy ASI for Knowledge Discovery in Microarrays (2007)

This paper presents two-way clustering of microarray data using fuzzy adaptive subspace iteration (ASI) based algorithm for knowledge discovery in microarrays. It is widely believed that each gene is involved in more than one cellular function or biological process. The proposed fuzzy ASI assigns a relevance value to each gene associated with each cluster. These functional categories are ranked based on their potential in providing maximal separation between the two tissues classes; which is an indication of differentially expressed genes (DEGs). Empirical analyses on simulated, 100 artificial microarray datasets are used to quantify the results obtained using the fuzzy-ASI algorithm. Further analyses on different microarray cancer datasets revealed several important genes that are relevant with various cancers.
Outcome of Surgical Management of Skull Base Tumors with Infratemporal Fossa Involvement (2009)

Background: Skull base tumors involving the infratemporal fossa comprise a wide variety of malignancies. These tumors were previously considered unresectable. By advent of new surgical techniques and immediate reconstruction, it is possible to resect tumors involving infratemporal fossa in an en block fashion and with low morbidity. The purpose of our study was to investigate the outcome of surgical management of this class of tumors.
<title>Packaging of photonic devices using laser welding</title> (1996)

Pulsed laser welding has proven to be the preferred bonding method that best facilitates the automated fiber alignment and bonding process of optoelectronic devices. However, a combination of considerations regarding (1) the high capital investment for a laser welding workstation (LWWS), (2) acquiring and developing the packaging technology for laser welding, and (3) the undeveloped demand in the market place have caused hesitation by many manufacturers in adopting the process. Typically, the majority of packages manufactured with laser welding have been higher-end priced devices. Further understanding and improvement of technical challenges, such as 'post-weld-shift' control, material selection, and package design, along with development of a cost-effective semi-automated LWWS are presenting a greater opportunity for a broader range of packages to be designed for laser welding, especially for low-cost singlemode datacom packages. The focus of the current work is to design a broad range of OE packages and develop a nanometer precision automation process for laser welding technology. The solution is recognized to be the combination of understanding the laser welding process, designing packages for laser welding, and developing an automation capability for manufacturing.
A New Remediation Model Based on Trusted Network (2008)

A new and feasible trusted remediation model was put forward, and the functions as well as the work flow of remediation model were explained in detail. Moreover, the communication and authentication process of remediation model were discussed. Simulations results show that by the proposed model, not only the safety and reliability of network can be ensured, but also the convenient and reliable remediation services are able to be provided to those terminals without according with the security policy of local network.
Improving networking performance in virtual mobile clouds (2012)

Mobile cloud computing uses cloud techniques for data storage and processing on behalf of mobile customers. It mitigates the mobile devices limitations in terms of battery and processing capacities. Virtualization is levereged in mobile clouds to enhance resource availability. However, it introduces an overhead that significantly harms the applications responsiveness. In this paper we propose an architecture for a mobile cloud where the mobile devices as well as the access network equipments are integrated in the cloud infrastructure through virtualization. The proposed architecture is enhanced with a novel scheme for network I/O virtualization. Through experimental performance evaluation, we show that our proposal considerably improves mobile devices networking performance in terms of delay and bandwidth when accessing virtual resources in the cloud.
Mobilization, Collection, and Processing of Autologous Peripheral Blood Stem Cells: Development of a Clinical Process with Associated Costs (2000)

We surveyed five academic medical centers to develop a clinical process for patients undergoing cytokine mobilization and leukapheresis prior to autologous peripheral blood stem cell transplantation. Costs were obtained from three centers and applied to each component of the pathway. Costs were divided into three categories: (1) pre-apheresis evaluation; (2) process of apheresis; (3) post-apheresis and peripheral blood stem cells processing. All centers participated in the development of the leukapheresis pathway. Because charges vary greatly among institutions, costs were determined from three of the institutions and a mean was calculated for each of the components of the process. Pre-apheresis costs consisted of central line placement, blood work, and the price of cytokine (rhG-CSF). Costs associated with apheresis included professional fees (for physicians and nurses), leukapheresis with stem cell cryopreservation, storage, sterility testing, analysis of circulating CD34+ cell counts, and 1 day of cytokine therapy. The post-apheresis process included thawing with sterility testing along with CD34+ cell number analysis and the performance of clonogenic assays. Total costs were as follows: (1) pre-apheresis, $2711; (2) apheresis, $2990; and, (3) post-apheresis/stem cell processing, $754. This survey from five academic medical centers provides the average costs associated with three main components of the apheresis procedure. Because many patients require multiple aphereses, interventions to achieve target CD34+ cell collections in as few collections as possible would result in significant cost reduction.
Measuring the concentration of uranium in the Qayyarah oilfield and refinery (2021)

In this research, the Concentrations of uranium and radon gas were measured in the samples collected from the Qayyarah refinery and field, which is located south of Mosul. The samples included soil and water associated with the production of oil, sludge and crude oil. After prepared samples, the radioactivity was measured using the CR-39 solid-state nuclear trace detector. Radon levels ranged between 10.79-19.67 in soil samples, and in water samples 7.25 , in sludge samples 13.42-16.96 and in crude oil 8.57 . While uranium concentration levels, ranged in soil samples from 0.870 - 1.457 , in water samples 0.585 , in sludge samples 1.299 - 1.369 , and in crude oil samples 0.692 . These results indicate that it is within the internationally permissible limits, as the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) determined the value of uranium in soil at 32 and in water at 50 , and the International Atomic Energy Agency (IAEA) determined the value of uranium in The slag has a value of and the International Association of Oil and Gas Producers (IOGP) has determined the value of uranium in crude oil and therefore does not pose any danger to the lives of workers in the refinery. field and environment.
The Multiple Waves of COVID-19 in Patients With Inflammatory Bowel Disease: A Temporal Trend Analysis (2022)

BACKGROUND: Cases of coronavirus disease 2019 (COVID-19) have emerged in discrete waves. We explored temporal trends in the reporting of COVID-19 in inflammatory bowel disease (IBD) patients. METHODS: The Surveillance Epidemiology of Coronavirus Under Research Exclusion for Inflammatory Bowel Disease (SECURE-IBD) is an international registry of IBD patients diagnosed with COVID-19. The average percent changes (APCs) were calculated in weekly reported cases of COVID-19 during the periods of March 22 to September 12, September 13 to December 12, 2020, and December 13 to July 31, 2021. RESULTS: Across 73 countries, 6404 cases of COVID-19 were reported in IBD patients. COVID-19 reporting decreased globally by 4.2% per week (95% CI, -5.3% to -3.0%) from March 22 to September 12, 2020, then climbed by 10.2% per week (95% CI, 8.1%-12.3%) from September 13 to December 12, 2020, and then declined by 6.3% per week (95% CI, -7.8% to -4.7%). In the fall of 2020, weekly reporting climbed in North America (APC, 11.3%; 95% CI, 8.8-13.8) and Europe (APC, 17.7%; 95% CI, 12.1%-23.5%), whereas reporting was stable in Asia (APC, -8.1%; 95% CI, -15.6-0.1). From December 13, 2020, to July 31, 2021, reporting of COVID-19 in those with IBD declined in North America (APC, -8.5%; 95% CI, -10.2 to -6.7) and Europe (APC, -5.4%; 95% CI, -7.2 to -3.6) and was stable in Latin America (APC, -1.5%; 95% CI, -3.5% to 0.6%). CONCLUSIONS: Temporal trends in reporting of COVID-19 in those with IBD are consistent with the epidemiological patterns COVID-19 globally.
Conformation of metalloporphyrins in solution (1970)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTConformation of metalloporphyrins in solutionCarlyle B. StormCite this: J. Am. Chem. Soc. 1970, 92, 5, 1423–1425Publication Date (Print):March 1, 1970Publication History Published online1 May 2002Published inissue 1 March 1970https://pubs.acs.org/doi/10.1021/ja00708a065https://doi.org/10.1021/ja00708a065research-articleACS PublicationsRequest reuse permissionsArticle Views93Altmetric-Citations18LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Bidirectional MHC molecule exchange between migratory and resident dendritic cells (2007)

Dendritic cells (DCs) loaded extracorporeally with antigen can be used as an adjuvant in vivo. In this work, we analyzed the migration of transferred DC and monitored the phenotype of new migrants in the draining lymph nodes. It is surprising that we found that a majority of resident DCs expressed donor MHC molecules and that a proportion of injected DCs acquired host MHC molecules. These observations suggest that a bidirectional MHC molecule exchange occurs between migratory and resident DCs, a mechanism that may amplify antigen presentation in vivo.
The use of Feedback Quantizer PWM for shaping inverter noise spectrum (2012)

There has been a continuous development of PWM strategies addressing different inverter topologies, as well as requirements of efficiency and minimal distortion. One of such strategies recently proposed by the authors is Feedback Quantizer PWM (FBQ-PWM). In this paper we briefly describe FBQ-PWM and its fundamental differences from other PWM techniques. We then present a detailed study of FBQ-PWM application to inverter noise shaping as to avoid a particular frequency or a number of frequencies in the harmonic spectrum of the output voltage. We illustrate our study with detailed simulations in physics-based Saber environment. The paper is concluded by a summary of its main findings and notes on practical implementation.
Pulsed laser photothermal spectroscopy of liquids and solids (1989)

Published papers have compared the advantages of piezoelectric and optical detection of photoacoustic signals in sample liquids and have demonstrated the superior capabilities of thermal lens measurements on time scales as short as a few hundred nanoseconds. Computer programs have been developed to compare theoretical and experimental photoacoustic pulse shapes in liquids with a view to determining triplet state quantum yields and radiationless decay lifetimes with greater accuracy. Non-radiative quantum yields of 1.0, 0.9 and 0.5 have been measured for nonaqueous solutions of Crystal Violet, Evan's Blue and Nile Blue A respectively. Pulsed photothermal radiometry experiments have yielded thermal diffusivity data for a room temperature molten salt system. Microphonic photoacoustic signals obtained by illuminating solid samples with synchrotron x-rays have been enhanced with volatile liquids, and the results have been compared with theory.
Microwave interferometer controls cutting depth of plastics (1969)

Microwave interferometer system controls the cutting of plastic materials to a prescribed depth. The interferometer is mounted on a carriage with a spindle and cutting tool. A cross slide, mounted on the carriage, allows the interferometer and cutter to move toward or away from the plastic workpiece.
Prospective Evaluation of Health Care Provider and Patient Assessments in Chemotherapy-Induced Peripheral Neurotoxicity (2021)

This study provides Class III evidence that a patient-completed questionnaire and nurse-assessed scale correlate with a physician-assessed scale.
EFFECT OF ANNUAL, BIENNIAL, AND TRIENNIAL IN-ROW SUBSOILING ON SOIL COMPACTION AND COTTON YIELD IN SOUTHEASTERN U.S. SILT LOAM SOILS (2005)

For those soils that require deep tillage to alleviate soil compaction, subsoiling can be an expensive andtime-consuming tillage event. Alternative tillage methods are needed which conserve natural resources without sacrificingcotton yields. An experiment was conducted in the Tennessee Valley region of north Alabama to determine how frequentlydeep tillage is needed to alleviate soil compaction problems in these soils. Three different subsoilers (an in-row subsoiler andtwo bentleg subsoilers) were tested against a no-till treatment to determine if differences in crop productivity or soil conditioncould be detected. Annual subsoiling resulted in reduced bulk density compared to biennial subsoiling, triennial subsoiling,or no subsoiling. Reductions in draft force were also found for annual subsoiling. However, cotton yield results over a two-yearperiod from tillage three-years previous, two-years previous, and one year previous found no differences.
Hydroxamic Acids Derived from 2-Hydroxy-2H-1,4-Benzoxazin-3(4H)-one: Key Defense Chemicals of Cereals (2009)

Many cereals accumulate hydroxamic acids derived from 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one. These benzoxazinoid hydroxamic acids are involved in defense of maize against various lepidopteran pests, most notably the European corn borer, in defense of cereals against various aphid species, and in allelopathy affecting the growth of weeds associated with rye and wheat crops. The role of benzoxazinoid hydroxamic acids in defense against fungal infection is less clear and seems to depend on the nature of the interactions at the plant-fungus interface. Efficient use of benzoxazinoid hydroxamic acids as resistance factors has been limited by the inability to selectively increase their levels at the plant growth stage and the plant tissues where they are mostly needed for a given pest. Although the biosynthesis of benzoxazinoid hydroxamic acids has been elucidated, the genes and mechanisms controlling their differential expression in different plant tissues and along plant ontogeny remain to be unraveled.
Percolation threshold of graphene nanosheets as conductive additives in Li4Ti5O12 anodes of Li-ion batteries (2013)

Graphene nanosheets (GNSs) have been considered as potential conductive additives for electrodes in Li-ion batteries to replace the existing carbon black (CB). Graphene has exceptionally high aspect ratio and excellent electrical conductivity, enabling the formation of extensive conductive networks at a much lower content than CB. This paper reports the beneficial effects of GNSs with a low percolation threshold on electrochemical performance of Li(4)Ti(5)O(12) (LTO) anodes. The experimental results show that the GNSs with a diameter of 46 μm and a thickness of 4.5 nm have a percolation threshold of 1.8 wt%. The prediction based on the interparticle distance concept gives a percolation threshold of 0.54 wt% for GNSs, which is almost an order of magnitude lower than that for CB particles. The substantially low percolation along with a high electrical conductivity of GNSs explains why the LTO anodes containing only 5 wt% GNSs deliver a much better rate capability than those with 15 wt% CB. However, a higher GNS content of 10 wt% results in re-stacking GNSs, deteriorating the diffusion of Li ions through the thickness of GNSs. The parametric study indicates that the percolation threshold of GNSs is inversely proportional to the aspect ratio of GNSs.
Probing Multiscale Transport and Inhomogeneity in a Lithium-Ion Pouch Cell Using In Situ Neutron Methods (2016)

We demonstrate the lithiation process in graphitic anodes using in situ neutron radiography and diffraction in a single-layer pouch cell. The variation in neutron absorption contrast in graphite shows a direct correlation between the degree of lithiation and the discharge potential. The experimental neutron attenuation line profiles across the graphite electrode at various discharge times (potentials) were compared with lithium concentration profiles computed using a 3D electrochemical transport model. In conjunction with imaging/radiography, in situ neutron diffraction was carried out to obtain information about the local structural changes during various stages of lithiation in carbon. Combined in situ radiography and diffraction supported by 3D multiscale electrochemical modeling opens up a powerful nondestructive tool that can be utilized to understand the multiscale nature of lithium transport as well as observe various inhomogeneities at a cell level.