gebhart/patrepeval huggingface dataset:
Neutron detection via thermoluminescence of Ce3+-doped CaO–Al2O3–B2O3 glass (2020)

For neutron detection applications, we have synthesised glass phosphor materials of Ce3+-doped CaO–Al2O3–B2O3 with consisting boron in two different forms of isotopes, enriched 10B and 11B, called 10B-glass and 11B-glass, respectively. For radiation detections, thermoluminescence (TL) properties of the glasses were investigated with X-ray, proton, and neutron irradiations. The TL properties of X-ray- and proton-irradiated 10B- and 11B-glasses were similar while the TL intensity of neutron-irradiated 10B-glass was much greater than that of 11B-glass. The TL of the 10B-glass was observed across the neutron fluence range of 107–1012 neutrons/cm2, and the intensity increased monotonically with neutron fluence.
Mutation spectrum of humanSLC39A4in a panel of patients with acrodermatitis enteropathica (2003)

Acrodermatitis enteropathica is rare autosomal recessive disorder characterized by a severe nutritional zinc deficiency. We and others have recently identified the human gene encoding an intestinal zinc transporter of the ZIP family, SLC39A4, as the mutated gene in acrodermatitis enteropathica (AE). A first mutation screening in 8 AE families (15 patients out of 36 individuals) revealed the presence of six different mutations described elsewhere. Based on these results, we have evaluated the involvement of SLC39A4 in 14 patients of 12 additional AE pedigees coming either from France, Tunisia, Austria or Lithuania. A total of 7 SLC39A4 mutations were identified (1 deletion, 2 nonsense, 2 missense, and 2 modifications of splice site), of which 4 are novel: a homozygous nonsense mutation in 3 consanguineous Tunisian families [c.143T>G (p.Leu48X)], a heterozygous nonsense mutation (c.1203G>A (p.Trp401X)) in a compound heterozygote from Austria also exhibiting an already known missense mutation, and distinct homozygous mutations in families from France or Tunisia [c.475-2A>G and c.184T>C (p.Cys62Arg)]. Furthermore, two other potential mutations [c.850G>A (p.Glu284Lys) and c.193-113T>C] were also observed at homozygous state in a French family formerly described. This study brings to 21 the number of reported SLC39A4 mutations in AE families.
TRIM32 modulates pluripotency entry and exit by directly regulating Oct4 stability (2015)

Induced pluripotent stem cells (iPSCs) have revolutionized the world of regenerative medicine; nevertheless, the exact molecular mechanisms underlying their generation and differentiation remain elusive. Here, we investigated the role of the cell fate determinant TRIM32 in modulating such processes. TRIM32 is essential for the induction of neuronal differentiation of neural stem cells by poly-ubiquitinating cMyc to target it for degradation resulting in inhibition of cell proliferation. To elucidate the role of TRIM32 in regulating somatic cell reprogramming we analysed the capacity of TRIM32-knock-out mouse embryonic fibroblasts (MEFs) in generating iPSC colonies. TRIM32 knock-out MEFs produced a higher number of iPSC colonies indicating a role for TRIM32 in inhibiting this cellular transition. Further characterization of the generated iPSCs indicated that the TRIM32 knock-out iPSCs show perturbed differentiation kinetics. Additionally, mathematical modelling of global gene expression data revealed that during differentiation an Oct4 centred network in the wild-type cells is replaced by an E2F1 centred network in the TRIM32 deficient cells. We show here that this might be caused by a TRIM32-dependent downregulation of Oct4. In summary, the data presented here reveal that TRIM32 directly regulates at least two of the four Yamanaka Factors (cMyc and Oct4), to modulate cell fate transitions.
A robust approach for sensor placement in automated vision dimensional inspection (2003)

Introduces a sensor placement approach for dimensional inspection with active visual inspection systems. For a given set of entities, an effective sensor plan includes parameter values that allow some entities to be observed simultaneously. Two kinds of approaches have generally been used for sensor planning in visual inspection systems: the generate-and-test method and the synthesis method. In order to have high performance and satisfactory accuracy, uncertainty must be considered in the sensing model of the visual system. Furthermore, in order to avoid sharp deterioration of the performance of the visual inspection system for very small disturbances of the parameters, an appropriate definition of robustness is proposed. In an experiment a new sensor planning approach based on robustness resolves some problems with earlier approaches.
Polyphenylsilsesquioxanes. New structures–new properties (2020)

The review describes the synthesis and properties of various forms of polyphenylsilsesquioxane (PPSQ). Among the forms described, we present the well-known ladder (l-PPSQ) and polyhedral (p-PPSQ) forms, from the first studies to the latest achievements. The practical prospects of these compounds and the possibility of their modification are estimated. These PPSQ have a regular polycyclic structure, which allowed us to compare them with random polycyclic analogs (r-PPSQ). The last part of the review describes the acyclic PPSQ (a-PPSQ) obtained recently. The methods for their synthesis and modification are presented. Modification of (a-PPSQ) allows two new forms of PPSQ to be obtained. The first one is a hyperbranched PPSQ. The second one is a globular PPSQ or a nanogel as it is called by the authors. Both forms are of great interest because their physicochemical properties differ greatly from the known ones (l-PPSQ, p-PPSQ, r-PPSQ). The areas of practical application of the new PPSQ forms are predicted.
THE USE OF BOUNDARY LUBRICANTS FOR THE REDUCTION OF PARTICLE JAMMING IN ABRASIVE PARTICLE SLURRIES FOR JET CUTTING (2017)

Thesis (Master's)--University of Washington, 2017-03
A. Survey of Entity Resolution and Record Linkage Methodologies (2015)

A great deal of research is focused on formation of a data warehouse. This is an important area of research as it could save many computation cycles and thus allow accurate information provided to the right people at the right time. Two considerations when forming a data warehouse are data cleansing (including entity resolution) and with schema integration (including record linkage). Uncleansed and fragmented data requires time to decipher and may lead to increased costs for an organization, so data cleansing and schema integration can save a great many (human) computation cycles and can lead to higher organizational efficiency. In this study we survey the literature for the methodologies proposed or developed for entity resolution and record linkage. This survey provides a foundation for solving many problems in data warehousing. For instance, little or no research has been directed at the problem of maintenance of cleansed and linked relations.
Knee Dislocation with Lateral Side Injury (2007)

The en masse surgical technique to repair the lateral side combined with an anterior cruciate ligament reconstruction after knee dislocation provides excellent long-term stability. The repaired lateral side and untreated posterior cruciate ligament heal with continuity. Patients can return to high levels of activity.
Real-Time Drilling Optimization Based on MWD Dynamic Measurements - Field Test Results (2003)

Real-time drilling optimization that relies solely on surface data has proven ineffective because it does not take into account the behavior of the BHA downhole. Surface weight-on-bit and rotary speed optimized for maximum penetration rate is of little use if it induces severe downhole vibration that results in costly damage to the BHA. An MWD drilling dynamics measurement tool is, therefore, a required component of a closed loop drilling control system (DCS). This paper presents the initial field-test results of a control system that uses a neural network for predictive control in drilling optimization. The system was tested on-line during a controlled field experiment at the Baker Hughes Experimental Test Area in Mounds, Oklahoma. Essentially, the system acquires surface and downhole data and generates quantitative advice (best weight-onbit and rotary speed, etc.) for the Driller. Key aspects of the field test were evaluating the performance of the DCS, and characterization of the formation being drilled by the downhole drilling dynamics measurements. During the test there was no real-time telemetry link between th eM WD sub and the surface, and data from an offset well was used successfully to describe the formation. The relationship between these formation parameters and the dynamic measurements was investigated off-line, once the dynamics information was retrieved at the surface. Such a scenario may be likely, at least in the short term, due to the time-delay in getting MWD information to surface. This successful field-test is an encouraging additional step towards real-time drilling optimization using a closed loop drilling control system.
Actes sans Comité de Lecture : "Study of the water diffusion in polymer membrane forming system during vapour induced phase separation process using in-situ analysis" (2005)

3rd Regional Symposium on Membrane Science and Technology - Bandung (Indonesia) - April, 26-27, 2005
APOPTOSIS OF MESENCHYMAL CELLS DURING THE PSEUDOGLANDULAR STAGE OF LUNG DEVELOPMENT AFFECTS BRANCHING MORPHOGENESIS (2008)

Apoptosis has been implicated as an important process in the development of several organ systems, including limbs, kidneys, and the heart. In developing murine lungs, the authors found that apoptosis was more predominant during the pseudoglandular stage of lung development than during the saccular stage, with 93% of the apoptotic structures in the mesenchyme. Murine lung explants cultured in the presence of zinc chloride and aurintricarboxylic acid, 2 blockers of endonuclease function, showed decreased branching. These observations suggest that apoptosis predominates in mesenchymal cells during the pseudoglandular stage of lung development, and may be important for normal progression of lung branching morphogenesis.
A Resilience-Building App to Support the Mental Health of Health Care Workers in the COVID-19 Era: Design Process, Distribution, and Evaluation (2021)

To address the mental health needs of HCWs during the COVID-19 pandemic, the Wellness Hub app was built and deployed throughout the Mount Sinai Health System. To our knowledge, this is the first resilience app of its kind. The Wellness Hub app is a promising proof of concept, with room to grow, for those who wish to build a secure mobile health app to support their employees, communities, or others in managing and improving mental and physical well-being. It is a novel tool offering mental health support broadly.
Epitaxial V-groove integrated circuit process (1972)

A new four-mask epitaxial V-groove (EVG) process for the fabrication of bipolar integrated circuits has been developed. The process utilizes non-critical epitaxial ν/N <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">+</sup> /N <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-</sup> layers and anisotropic etching of silicon to eliminate the buried layer and isolation diffusions as well as the need for masking the base diffusion of the standard planar epitaxial bipolar integrated circuit process. NPN transistor, resistor, and Schottky diode characteristics are equivalent to or exceed those of the standard process. Parasitic collector-substrate capacitance is reduced to a minimum by the use of a near-intrinsic (ν) epitaxial layer between the buried layer and substrate. Side-wall capacitance is eliminated completely. Shallower high-voltage structures can be made. Collector series resistance can be reduced significantly by direct contact to the buried layer. The area of an NPN EVG transistor is less than 50% the area of a comparable NPN epitaxial planar device. A five-mask epitaxial V-groove process produces lateral PNP transistors which are superior to those of the four-mask process.
Design and Demonstration of a 5-Bit Flash-Type SFQ A/D Converter Integrated With Error Correction and Interleaving Circuits (2010)

We have designed a fully integrated 5-bit flash-type single-flux quantum (SFQ) analog-to-digital converter (ADC), in which an error correction and a bit-interleaving circuit are integrated with complementary quasi-one-junction SQUID (CQOS) comparators, and we verified its operation in experiments. Two types of look-back error correction circuits with different clock schemes were designed for the integrated ADCs to avoid the gray zone in comparators and to convert gray code to binary code. The interleaving circuit was also used in the ADC to add one extra bit. A binary 5-bit A/D converter was integrated into an IC chip. Then, input waveforms at low frequencies were successfully retrieved from the binary data of the A/D converter without any errors. We also confirmed that the A/D converter operated properly by conducting tests in our cryocooling system using a 4K-GM cryocooler after the chip was flip-chip bonded onto a multi-chip-module (MCM) carrier. We also used the beat frequency method to test and confirm that the CQOS comparator operated effectively at high frequency, i.e., 3 bits at 15 GHz in the binary code operation and 4 bits at 15 GHz in the gray code operation. Furthermore, operations at sampling frequencies of up to 32 and 50 GHz with a low-frequency analog input signal were experimentally confirmed for a 4-bit comparator circuit with a critical current density J <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">c</sub> of 2.5 kA/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> and 10 kA/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> , respectively.
Pre-Weaning Growth Hormone Treatment Ameliorates Bone Marrow Macrophage Inflammation in Adult Male Rat Offspring following Maternal Undernutrition (2013)

Maternal undernutrition (UN) is associated with the development of obesity and metabolic complications in adult offspring. While the role of inflammation in obesity and related comorbidities has been well established, there is little evidence regarding the effects of maternal UN-induced programming on immune function in male adult offspring. This study examines the effects growth hormone (GH), which is known to induce anti-inflammatory effects, on maternal UN-induced bone marrow macrophage (BMM) function in adult male offspring. Sprague-Dawley rats were assigned to chow (C) or UN (50% ad libitum; UN) diet throughout gestation. Male C and UN pups received saline (CS/UNS) or GH (2.5 µg/g/d; CGH/UNGH) from day 3-21. Bone marrow hematopoietic cells were differentiated to a macrophage phenotype in the presence of M-CSF (50 ng/ml). Differentiated bone marrow macrophages (BMM) were stimulated with LPS (100 ng/ml) for 6 h. UNS-derived BMM had significantly increased secretion and expression of IL-1β and IL-6 following LPS stimulation. This was accompanied by increased expression of IL-1R1, IL-6R and TLR4. Pre-weaning GH treatment reversed this pro-inflammatory phenotype. Furthermore UNGH displayed increased expression of markers of alternative (M2) macrophage activation, mannose receptor and PPARγ. This study demonstrates that fetal UN exposure primes hematopoietic immune cells to a more potent pro-inflammatory phenotype with heightened cytokine secretion and receptor expression. Furthermore these cells are pre-disposed to pro-inflammatory M1 macrophage phenotype which has wide-reaching and important effects in terms of obesity and metabolic disease.
A Contrastive Framework for Neural Text Generation (2022)

Text generation is of great importance to many natural language processing applications. However, maximization-based decoding methods (e.g. beam search) of neural language models often lead to degenerate solutions -- the generated text is unnatural and contains undesirable repetitions. Existing approaches introduce stochasticity via sampling or modify training objectives to decrease probabilities of certain tokens (e.g., unlikelihood training). However, they often lead to solutions that lack coherence. In this work, we show that an underlying reason for model degeneration is the anisotropic distribution of token representations. We present a contrastive solution: (i) SimCTG, a contrastive training objective to calibrate the model's representation space, and (ii) a decoding method -- contrastive search -- to encourage diversity while maintaining coherence in the generated text. Extensive experiments and analyses on three benchmarks from two languages demonstrate that our proposed approach significantly outperforms current state-of-the-art text generation methods as evaluated by both human and automatic metrics.
Partitioning Multi-Threaded Processors with a Large Number of Threads (2005)

Today's general-purpose processors are increasingly using multithreading in order to better leverage the additional on-chip real estate available with each technology generation. Simultaneous multi-threading (SMT) was originally proposed as a large dynamic superscalar processor with monolithic hardware structures shared among all threads. Inters hyper-threaded Pentium 4 processor partitions the queue structures among two threads, demonstrating more balanced performance by reducing the hoarding of structures by a single thread. IBM's Power5 processor is a 2-way chip multiprocessor (CMP) of SMT processors, each supporting 2 threads, which significantly reduces design complexity and can improve power efficiency. This paper examines processor partitioning options for larger numbers of threads on a chip. While growing transistor budgets permit four and eight-thread processors to be designed, design complexity, power dissipation, and wire scaling limitations create significant barriers to their actual realization. We explore the design choices of sharing, or of partitioning and distributing, the front end (instruction cache, instruction fetch, and dispatch), the execution units and associated state, as well as the L1 Dcache banks, in a clustered multi-threaded (CMT) processor. We show that the best performance is obtained by restricting the sharing of the L1 Dcache banks and the execution engines among threads. On the other hand, significant sharing of the front-end resources is the best approach. When compared against large monolithic SMT processors, a CMT processor provides very competitive IPC performance on average, 90-96% of that of partitioned SMT while being more scalable and much more power efficient. In a CMP organization, the gap between SMT and CMT processors shrinks further, making a CMP of CMT processors a highly viable alternative for the future
Visible photoluminescence from He-implanted silicon (1995)

Visible photoluminescence has been observed at cryogenic temperatures from crystalline Si bombarded with He and exposed to H either as plasma or gas in the 250–450 °C temperature range. The experimental results are consistent with the formation of Si nanoparticles produced by He segregation, which is responsible for exciton localization, and H passivation of the nonradiative recombination centers.
On-Road Remote Sensing of Vehicle Emissions in Mexico (1997)

In 1991, the nation of Mexico lowered light-duty vehicle emission standards leading to the introduction of catalytic convertors. On-road emissions were measured in Monterrey, Nuevo Léon, Mexico in 1995 from more than 24 000 vehicles. The Subsecretaría de Ecología's Office was able to provide vehicle registration information for 10 654 vehicles. These data show a steady emission reduction that coincides with the introduction of light-duty vehicle exhaust emission standards for Mexican vehicles and the implementation of Monterrey's I/M program. The 1995 models are emitting 75% less CO, 70% less HC, and 65% less NO than precontrol models. Pre-1995 models appear to experience a steady degradation in their emission control capabilities, but the cause of this observation cannot reliably be determined without additional data. Comparisons to other locations reveal that Monterrey and Mexico City have improved their fleet emissions when compared to Juárez despite a shorter time with access to vehicles manufactured with emission control systems. The Monterrey data set can also be used to help explain some of the large on-road reductions observed in Mexico City between 1991 and 1994. Sweden's experience in introducing three-way closed-loop emission control systems suggests that the service life of Mexican vehicle emission control systems can be improved.
An empirical analysis of the decision-making of forgoing life-sustaining treatments for patients with advanced dementia in the United States (2005)

2005-2006 > Academic research: refereed > Publication in refereed journal
THE NEAR AND INTERMEDIATE FIELD OF A ROUND FREE JET: THE EFFECT OF REYNOLDS NUMBER AND MIXING TRANSITION (2009)

Flying and stationary hot wire measurements were made to investigate the effect of the Reynolds number on the near and intermediate fields, ( 0 ≤ x/D ≤ 25 ), of a round free jet. Measurements were carried out over a range of Reynolds numbers, based on the jet exit mean velocity and the nozzle diameter, that span the mixing transition. The specific Reynolds numbers tested were 6,000, 10,000, 30,000, 50,000 and 100,000. The objective of this study was to outline the variation of the different micoscales in the near and intermediate-fields. Results showed that the length of the potential core region decreases with increasing the Reynolds number. The axial mean velocity reaches the self-similar state faster than the turbulence intensities. The range of frequencies that comprise the inertial subrange increases with distance downstream from the jet inlet. The Reynolds number range considered clearly pointed to a mixing transition at Reynolds numbers above ~20,000. This was accompanied by the appearance of the inertial subrange. At Reynolds numbers below the mixing transition, the energy of the large scale turbulence proceeds directly to the dissipation range. Considering the energy spectra distribution and the development of the different length scales, the mixing transition was found to be a local phenomenon.
DOA estimation exploiting coprime frequencies (2014)

Coprime array, which utilizes a coprime pair of uniform linear subarrays, is an attractive structure to achieve sparse array configurations. Alternatively, effective coprime array configurations can be implemented using a uniform linear array with two coprime sensing frequencies. This enables the integration of the coprime array and filter concepts to achieve high capabilities in meeting system performance and complexity constraints. This paper examines its performance for direction-of-arrival estimations. In particular, we analyze the number of detectable signals and the estimation accuracy as related to the array configurations and sensing frequencies.
MIMO capacity of antenna arrays evaluated using radio channel measurements, reverberation chamber and radiation patterns (2007)

We compare different methods of evaluating arrays for multiple-input multiple-output (MIMO) systems through calculation of the MIMO capacity of a compact antenna array for mobile or WLAN applications at 1766 MHz and comparing it to a reference array of four monopoles. Three different methods were used: evaluation using radiation patterns and a channel model, measurements in a reverberation chamber and simultaneous measurement of radio channel data using the two arrays. We conclude that all methods give very similar relative results and that the main difference in the two arrays is the 1.3 dB lower radiation efficiency of the compact array. The channel measurements also show that the arrays provide between 80% and 90% of the capacity of a 4×4 MIMO system.