gebhart/patrepeval huggingface dataset:
Gene expression in the mammary gland of the tammar wallaby during the lactation cycle reveals conserved mechanisms regulating mammalian lactation (2015)

The tammar wallaby (Macropus eugenii), an Australian marsupial, has evolved a different lactation strategy compared with eutherian mammals, making it a valuable comparative model for lactation studies. The tammar mammary gland was investigated for changes in gene expression during key stages of the lactation cycle using microarrays. Differentially regulated genes were identified, annotated and subsequent gene ontologies, pathways and molecular networks analysed. Major milk-protein gene expression changes during lactation were in accord with changes in milk-protein secretion. However, other gene expression changes included changes in genes affecting mRNA stability, hormone and cytokine signalling and genes for transport and metabolism of amino acids and lipids. Some genes with large changes in expression have poorly known roles in lactation. For instance, SIM2 was upregulated at lactation initiation and may inhibit proliferation and involution of mammary epithelial cells, while FUT8 was upregulated in Phase 3 of lactation and may support the large increase in milk volume that occurs at this point in the lactation cycle. This pattern of regulation has not previously been reported and suggests that these genes may play a crucial regulatory role in marsupial milk production and are likely to play a related role in other mammals.
A secure NFC application for credit transfer among mobile phones (2012)

People continuously try to improve their quality of life and technologies have an important role on it. Money transaction between mobile devices is bored and a difficult operation to perform since there is not a simple and safe way to do it. Near field communication (NFC) is a new secure short-range wireless connectivity technology, can play an important role on this kind of issues, and it is very easy to use. In upcoming years the NFC technology can offer an important contribution to simplify some daily operations, such as payments and money transactions. This paper focused on NFC technology and proposes a peer-to-peer based application that demonstrates the usage of NFC and Bluetooth technologies for money transaction between mobile devices. NFC technology is used with a simple gesture that triggers a lot of background operations. A solution is proposed, evaluated, and demonstrated and it is ready for use. It demonstrates the NFC availability for secure and easy communication and authentication in mobile applications.
Analysis of Heterogeneity of Human Eosinophils (1989)

To identify different subpopulations of human eosinophils, we examined the presence of FcεR II and a new granulocyte-specific antigen, which was detected by an anti-human eosinophil antibody AE 500, in the eosinophils. We prepared human blood eosinophils (>98% pure) by using a fluo-rescence-activated cell sorter to minimize the contamination of other leukocytes into the eosinophils. The anti-human eosinophil monoclonal antibody AE 500 (IgM, κ) was raised by immunizing mice with eosinophils from hypereosinophilic patients. We found that FcεR II was exclusively present in hypodense blood eosinophils, but not in normodense eosinophils. The antibody AE 500 reacted with eosinophils from hypereosinophilic patients, but not with those from nomal subjects, suggesting that eosinophils in the hypereosinophilic state might be at a different differentiation stage and express an antigen detected by the antibody. To determine whether the differentiation antigen is expressed during the differentiation of eosinophils from the precursors to blood eosinophils, we also examined the presence of FcεR II and an antigen detected by AE 500 in IL-3-and IL-5-induced cord blood-derived eosinophils. Neither FcεR II nor AE 500 reactive antigen was present in the cord blood-derived eosinophils. It is suggested that these two antigens of human eosinophils might be transiently expressed during the differentiation.
Boron Nitride Membranes with a Distinct Nanoconfinement Effect for Efficient Ethylene/Ethane Separation (2019)

A BN membrane with a distinct nanoconfinement effect toward efficient ethylene/ethane separation is presented. The horizontal and inclined self-assembly of 2D BN nanosheets endow the BN membrane with abundant percolating nanochannels, and these nanochannels are further decorated by reactive ionic liquids (RILs) to tailor their sizes as well as to achieve nanoconfinement effect. The noncovalent interactions between RIL and BN nanosheets favor the ordered alignment of the cations and anions of RIL within BN nanochannels, which contributes to a fast and selective ethylene transport. The resultant membranes exhibit an unprecedented separation performance with superhigh C<sub>2</sub> H<sub>4</sub> permeance of 138 GPU and C<sub>2</sub> H<sub>4</sub> /C<sub>2</sub> H<sub>6</sub> selectivity of 128 as well as remarkably improved long-term stability for 180 h, outperforming reported state-of-the-art membranes.
Ionophore activity of sarcotoxin I, a bactericidal protein of Sarcophaga peregrina (1985)

When Escherichia coli was treated with sarcotoxin I, a potent bactericidal protein of Sarcophaga peregrina (fleshfly), K+ inside of the cells leaked out rapidly and the ATP pool of the cells rapidly decreased. These results suggested that the bactericidal effect of sarcotoxin I was due to its ionophore activity, and that it blocked the generation of ATP by inhibiting formation of the proton gradient essential for oxidative phosphorylation. This was confirmed by use of an uncA mutant, which was much less susceptible than the wild-type strain to sarcotoxin I under fixed ionic conditions.
Eine quantitative Abschätzung elektrisch aktivierter Fiberpopulationen am Beispiel der Karussellstimulation - Quantitative Assessment of the Fibre Population Activated by Round about Stimulation (1987)

Article Eine quantitative Abschätzung elektrisch aktivierter Fiberpopulationen am Beispiel der Karussellstimulation - Quantitative Assessment of the Fibre Population Activated by Round about Stimulation was published on January 1, 1987 in the journal Biomedical Engineering / Biomedizinische Technik (volume 32, issue 7-8).
Television Camera Tubes and Solid-State Sensors for Broadcast Applications (1986)

For use in broadcast cameras, the small size, low lag, acceptable signal-to-noise ratio, and long life of the solid-state sensor offer distinct advantages over the relatively large size and limited life of the camera tube. The availability of small Plumbicon <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">®</sup> tubes with blemish-free, low-noise pictures, however, will prolong the use of color cameras with tubes for at least a few more years. For high-performance cameras and HDTV, tubes are currently superior because of their higher resolution. This article compares typical solid-state sensor performance with that of camera tube performance.
<title>Novel fiber optic sensor array based on the Sagnac interferometer</title> (1999)

We present a novel concept for an acoustic fiber sensor array based on the Sagnac interferometer. Its characteristics and performance are analyzed theoretically and shown to be superior in several important areas to standard sensor arrays based on Mach-Zehnder (MZ) interferometers. In particular, the Sagnac sensor array (SSA) exhibits a stable bias point, a reduced conversion of source phase noise into intensity noise, a frequency response matched to the ambient ocean noise (of relevance for underwater acoustic sensing), and freedom from polarization-induced signal fading. The dynamic range of the SSA can also be easily designed to far exceed the dynamic range of a MZSA.
Neoplastic meningitis: a rare presentation of bronchial adenocarcinoma. (2011)

Following chronic daily headache, neoplastic meningitis was diagnosed in a non-smoking 44-year-old man. A bronchial adenocarcinoma was found to be the primary tumor. He was treated with erlotinib. Meningitis as the first manifestation of a malignancy is very rare.
Frequent Alteration of MLL3 Frameshift Mutations in Microsatellite Deficient Colorectal Cancer (2011)

We found that frameshift mutations of MLL3 in both CRC cells and primary tumor that were more common in cases with microsatellite instability. Moreover, we have shown CpG island-associated promoter of MLL3 gene has no DNA methylation in CRC cells but also primary tumor and normal colon, and this region has a highly homologous of pseudo gene (psiTPTE22) that was age relate DNA methylation.
Automated dual band patch antenna design by a genetic algorithm based numerical code (2002)

In this contribution a new automated approach for dual-band patch antenna design is presented. Starting from a rectangular patch shape (mother structure), genetic algorithms (GA) are adopted to detect, among all the possible shapes (child structures) that can be obtained from the mother structure, the optimal patch shape matching some given requirements without having to examine the whole set of child shapes. In order to analyse the mother rectangular patch frequency behaviour, the method of moments (MoM) in the spatial domain is employed and, then, such an analysis is used for the GA research procedure. As an example of the code synthesis capabilities, the design of a dual band patch is finally presented.
ESTUDO QUÍMICO DAS FOLHAS DE STYRAX FERRUGINEUS. (2015)

Styrax pertence a Styracaceae que e composta por aproximadamente 130 especies. Estudos fitoquimicos anteriores de S. ferrugineus revelaram a ocorrencia de lignanas, neolignanas, esteroides e triterpenos. Onde, as lignanas benzofurânicas, homoegonol e egonol, apresentaram principalmente atividade antimicrobiana e citotoxica, o que evidencia a importância do estudo desta especie. Neste trabalho o objetivo principal e o estudo fitoquimico das partes aereas de S. ferrugineus . Assim, o material vegetal (358,5 g) material vegetal foi submetido a extracao a temperatura ambiente, por maceracao com etanol durante 3 dias, com tres repeticoes, e concentrados em evaporador rotatorio fornecendo 45,2 g de extrato bruto. Uma parte do extrato bruto (20 g) foi dissolvida em 500 mL de MeOH-H 2 O (8:2, v/v) e submetida a particao liquido-liquido com hexano, AcOEt e n -butanol. Deste procedimento foram obtidas as fracoes: hexânica (2,2 g), AcOEt (2,9 g), n -butanolica (12,4 g) e hidrometanolica (2,5 g). A fracao AcOEt apos coluna cromatografica com Sephadex LH-20 resultou no isolamento dos flavonoides quercetina e kaepferol.
Sensitivity of MRI signal distribution within the intervertebral disc to image segmentation and data normalisation (2013)

There is a lack of early biomarkers of intervertebral disc (IVD) degeneration. Thus, the authors developed the analysis of magnetic resonance signal intensity distribution (AMRSID) method to analyse the 3D distribution of the T2-weighted MR signal intensity within the IVD using normalised histograms, weighted centres and volume ratios. The objective was to assess the sensitivity of the AMRSID method to the segmentation process and data normalisation. Repetition of the semi-automatic segmentation by the same operator did not influence the quality of the contour or our new MR distribution parameters whereas the skills of the operator influenced only the MR distribution parameters, and the instructions given prior to the segmentation influenced both the quality of the contour and the MR distribution parameters. Bone normalisation produces an index that jointly highlights IVD and bone health, whereas cerebrospinal fluid normalisation only suppresses the effect of the acquisition gain. This robust AMRSID method has the potential to improve the diagnostic with earlier biomarkers and the prognosis of evolution.
Applications of digital signal processing (1978)

Applications of digital signal processing , Applications of digital signal processing , مرکز فناوری اطلاعات و اطلاع رسانی کشاورزی
The Immunohistochemical Analysis for the Expression of Survivin, HSP, and Bcl-2 in Non-small Cell Lung Carcinoma (2002)

Background Anti-apoptotic proteins may be involved in tumor development, progression and the response to treatment. Bcl-2 is by far the most studied anti-apoptotic protein. A novel infibitor of apoptosis, designat ed survivin, and the heat shock proteins (HSPs) have recently been found in many human cancers. Immunohistochemical methods were used to determine the expression level of survivin, HSP 70 and bcl-2 in non-small cell lung cancer (NSCLC) to evaluate their clinical significance. Methods Tissue array slides were obtained from 99 surgically resected NSCLCs. Immunohistochemical staining was performed by an immuno-peroxidase technique using an avidin-biotinylated horseradish peroxidase complex. Anti-survivin rabbit polyclonal antibodies, anti-HSP70 mouse monoclonal antibodies and anti-bcl-2 mouse monoclonal antibodies were used as the primary antibodies. Results Positive ataining of survivin was detected in 33.3% of the cases. Survivin positivity is associated with to females and recurrence. A nonstatistically significant trend toward increased survivin expression was observed in non-smokers, and its expression inversely correlated with the number of cigarettes smoked in smokers. HSP70 was detected in 84.8% but this did not correlate with the clinicopathologic characteristics. Bcl-2 was detected in 18.2% and its and its expression correlated to tumor recurrence. No significant difference in the median survival time was noted in a comparison of al cases with survivin expression and those without. There was no association betwwen HSP70 or bcl-2 expression and survival. Conclusions Survivin expression was significantly associated with females and tumor recurrence. In addition its expression was inversely associated with the number of cigarettes smoked. However, HSP70 and bcl-2 expression were not associated with the clinical parameters or survival. This suggests that measuring the survivin levels may be useful in identifying patients at high risk for disease recurrence. Therefore, survivin might be a new diagnostic/therapeutic target in cancer.
3D SURFACE RECONSTRUCTION BASED ON COMBINED ANALYSIS OF REFLECTANCE AND POLARISATION PROPERTIES: A LOCAL APPROACH (2005)

An image-based 3D surface reconstruction technique based on simultaneous evaluation of reflectance and polarisation features is introduced in this paper. The proposed technique is suitable for single and multi-image (photopolarimetric stereo) analysis. It is especially suited for the difficult task of 3D reconstruction of rough metallic surfaces with non-Lambertian reflectance. The reflectance and polarisation properties are used to determine the surface gradients in dividually for each image pixel. The presented multi-image technique is invariant to variations of the surface albedo. We evaluate our algorithm based on synthetic ground truth data as well as on a raw forged iron surface. The results we obtain for the real world example demonstrate the applicability of our method in the domain of industrial quality inspection.
Well-Differentiated Papillary Mesothelioma of the Peritoneum Is Genetically Distinct from Malignant Mesothelioma (2020)

Well-differentiated papillary mesothelioma (WDPM) is an uncommon mesothelial proliferation that is most commonly encountered as an incidental finding in the peritoneal cavity. There is controversy in the literature about whether WDPM is a neoplasm or a reactive process and, if neoplastic, whether it is a variant or precursor of epithelial malignant mesothelioma or is a different entity. Using whole exome sequencing of five WDPMs of the peritoneum, we have identified distinct mutations in <i>EHD1</i>, <i>ATM</i>, <i>FBXO10</i>, <i>SH2D2A</i>, <i>CDH5</i>, <i>MAGED1</i>, and <i>TP73</i> shared by WDPM cases but not reported in malignant mesotheliomas. Furthermore, we show that WDPM is strongly enriched with C > A transversion substitution mutations, a pattern that is also not found in malignant mesotheliomas. The WDPMs lacked the alterations involving <i>BAP1</i>, <i>SETD2</i>, <i>NF2</i>, <i>CDKN2A/B</i>, <i>LASTS1/2</i>, <i>PBRM1</i>, and <i>SMARCC1</i> that are frequently found in malignant mesotheliomas. We conclude that WDPMs are neoplasms that are genetically distinct from malignant mesotheliomas and, based on observed mutations, do not appear to be precursors of malignant mesotheliomas.
Physicochemical Properties of Physical Chitin Hydrogels:  Modeling and Relation with the Mechanical Properties (2001)

In this work, we were interested in the modeling of syneresis of physical chitin hydrogels by a mathematic law allowing us to predict the variation of the weight of the gel as a function of time. The variation of the weight of the gel during syneresis can be described by W(t)()/W(0) = (t(1/2) + (W(infinity)/W(0))t)/(t(1/2)) + t) where W(0), W(infinity), and W(t)() are the weights of the gel at the beginning of syneresis, for infinite time and for a time t, respectively. t(1/2) corresponds to the half-time of syneresis. W(infinity)/W(0) and t(1/2) were studied in relation with several parameters such as the ionic strength, pH, degree of acetylation of chitin and the initial concentration of polymer. The mechanical properties of chitin hydrogels maintained during syneresis in media of different pH's and ionic strengths were also investigated.
Clinicopathologic features of synchronous multifocal early gastric cancers. (1997)

The clinicopathologic features of patients with 47 synchronous multifocal early gastric cancers were reviewed retrospectively from hospital records between 1969 and 1994. These patients were then compared to 587 patients with solitary early gastric cancers. Accessory lesions were missed preoperatively in 15 of the 47 patients with multifocal early gastric cancers. Multifocal early gastric cancer was significantly more common in slightly older patients (multifocal versus single: 65.19 +/- 10.65 years versus 59.22 +/- 11.7 years (p = 0.004). Elevated lesions and the intestinal type of cancer were found more frequently in multifocal early gastric cancers than in solitary cancers (p < 0.005). The tumor location was higher in multiple early gastric cancers than in solitary cancers (p < 0.05). The postoperative survival did not differ between the two groups. We conclude that when planning the surgical treatment of early gastric cancers in the elderly, the whole stomach should be evaluated before and during the operation, and after the resected stomach examined.
[2,2′-[1,1,2,2-Tetramethyl-1,2-ethanediylbis(nitrilomethylidyne)]]bis[phenolato] Nitrido Manganese (2002)

[174092-29-6] C20H22MnN3O2 (MW 391.35) InChI = 1S/C20H24N2O2.Mn.N/c1-19(2,21-13-15-9-5-7-11-17(15)23)20(3,4)22-14-16-10-6-8-12-18(16)24;;/h5-14,23-24H,1-4H3;;/q;+2;/p-2/b21-13+,22-14+;; InChIKey = HTNYOBWVVINUDY-FDOBHKDXSA-L (reagent used, following activation, as nitrogen atom transfer reagent to alkenes1) Physical Data: mp >260 °C. Solubility: slightly soluble in alcohols; soluble in dichloromethane, and most organic solvents. Preparative Methods: prepared in one pot by mixing saltmen ligand with manganese(II) acetate in methanol followed by addition of aqueous ammonia and subsequent oxidation with Clorox bleach.2 Purification: chromatography over basic alumina and recrystallization from EtOH/hexane. Handling, Storage, and Precautions: stable to both air and H2O at room temperature. No known toxicity.
ChemInform Abstract: Rhodium‐Catalyzed Asymmetric 1,4‐Addition of Organoboron Reagents to 5,6‐Dihydro‐2(1H)‐pyridinones. Asymmetric Synthesis of 4‐Aryl‐2‐piperidinones. (2002)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Azo Compounds. XXXII.1 Kinetics of the Thermal Decomposition of Phenylphenylsulfonyl Diimide (1960)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAzo Compounds. XXXII.1 Kinetics of the Thermal Decomposition of Phenylphenylsulfonyl DiimideArnold J. Rosenthal and C. G. OverbergerCite this: J. Am. Chem. Soc. 1960, 82, 1, 108–117Publication Date (Print):January 1, 1960Publication History Published online1 May 2002Published inissue 1 January 1960https://pubs.acs.org/doi/10.1021/ja01486a024https://doi.org/10.1021/ja01486a024research-articleACS PublicationsRequest reuse permissionsArticle Views132Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Synthesis and anisotropic magnetism in quantum spin liquid candidates AYbSe2 (A = K and Rb) (2021)

The quantum spin liquid (QSL) state in rare-earth triangular lattices has attracted much attention recently due to its potential application in quantum computing and communication. Here, we report the single-crystal growth synthesis, crystal structure characterizations, and magnetic properties of AYbSe2 (A = K and Rb) compounds. The x-ray diffraction analysis shows that AYbSe2 (A = K and Rb) crystallizes in a trigonal space group, R-3m (No. 166) with Z = 3. AYbSe2 possesses a two-dimensional (2D) Yb–Se–Yb layered structure formed by edged-shared YbSe6 octahedra. The magnetic properties are highly anisotropic for both title compounds, and no long-range order is found down to 0.4 K, revealing the possible QSL ground state in these compounds. The isothermal magnetization exhibits a one-third magnetization plateau when the magnetic fields are applied in the ab-plane. Heat capacity is performed along both ab-plane and c axis and features the characteristic dome for triangular magnetic lattice compounds as a function of magnetic fields. Due to the change in the interlayer and intralayer distance of Yb3+, the dome shifts to low fields from KYbSe2 to RbYbSe2. All these results indicate that the AYbSe2 family presents unique frustrated magnetism close to the possible QSL and noncollinear spin states.
ChemInform Abstract: Organic Chemistry One Catalyst, Two Reactions (2015)

Abstract Review: 6 refs.
Benzodiazepines and disinhibition: a review (2002)

AIMS AND METHODS To describe and attempt to quantify the incidence of disinhibitory reactions to benzodiazepines and to identify those at risk. Medline search, 1966–January 2002. Results The overall incidence of disinhibitory reactions is small, but those with impulse control problems, neurological disorders, learning disabilities, the under 18s and the over 65s are at significant risk. Clinical Implications It is important to be aware of the ability of benzodiazepines to cause behavioural disinhibition and to maintain a high degree of vigilance when these drugs are administered to patients known to be at risk. In patients who have experienced behavioural disinhibition with benzodiazepines, antipsychotic drugs should be used to modify behaviour in any future emergencies.