gebhart/patrepeval huggingface dataset:
Récepteur radiofréquence basé sur l’échantillonnage parcimonieux pour de l'extraction de caractéristiques dans les applications de radio cognitive (2018)

This work deals with the topic of radiofrequency receivers based on Compressive Sampling for feature extraction in Cognitive Radio.Compressive Sampling is a paradigm shift in analog to digital conversion that bypasses the Nyquist sampling frequency.In this work, estimations are carried out directly on the compressed samples due to the prohibitive cost of signal reconstruction.First, the receiver architecture is considered, in particular through the choice of the mixing codes of the Modulated Wideband Converter.A high-level analysis on properties of the sensing matrix, coherence to reduce the number of measurement and isometry for noise robustness,is carried out and validated by a simulation platform.Finally, parametric estimation based on compressed samples is tackled through the prism of the Cram'{e}r-Rao lower bound on unbiased estimators.A closed form expression of the Fisher matrix is established under certain assumptions and enables to dissociate the effects of compression and diversity creation.The influence of Compressive Sampling on estimation bounds, in particular coupling between parameters and spectral leakage, is illustrated by the example.
Glucuronoyl esterase facilitates biomass degradation in <i>Neurospora crassa</i> by upregulating the expression of plant biomass-degrading enzymes (2022)

Glucuronoyl esterase (GE) is a promising agent for the delignification of plant biomass since it has been shown to cleave the linkage between xylan and lignin in vitro. In this study, we demonstrate that NcGE, a GE from Neurospora crassa, stimulates plant biomass degradation. In vitro, NcGE synergistically increased the release of reducing sugars from plant biomass when added together with cellulase or xylanase. In vivo, overexpression of NcGE in N. crassa resulted in an increase in xylanolytic activity. Consistently, elevated transcription of genes encoding the major plant biomass degrading-enzymes (PBDEs) was observed in the NcGE overexpression strain. Increased xylanolytic activity and transcription of PDBE genes were largely abolished when the transcription factors clr-1, clr-2, or xlr-1 were deleted. Interestingly, the expression of some PBDE genes was increased when the hydrolysate of plant biomass by NcGE was added to the culture medium. We propose that NcGE boosts the production of PBDEs through the activation of key transcription factors, which is presumably caused by NcGE-mediated generation of hypothetical inducer(s) from plant biomass.
First observations of power MOSFET burnout with high energy neutrons (1996)

Single event burnout was seen in power MOSFETs exposed to high energy neutrons. Devices with rated voltage /spl ges/400 volts exhibited burnout at substantially less than the rated voltage. Tests with high energy protons gave similar results. Burnout was also seen in limited tests with lower energy protons and neutrons. Correlations with heavy-ion data are discussed. Accelerator proton data gave favorable comparisons with burnout rates measured on the APEX spacecraft. Implications for burnout at lower altitudes are also discussed.
Kinetic study on coal cleaning by froth flotation. (1986)

The objective of this research is to develop a new froth flotation method to be employed in CWM (Coal Water Mixture) preparation. The froth flotation method is famous for practical coal cleaning, but it has some problems relating to CWM preparation. In conventional flotation method, deashed coals tend to coagulate because much oil used as a collector is included in them. Therefore, it seems to be difficult to disperse the deashed coals into water in preparing CWM. Accordingly, its important to increase the carbon recovery rate by making use of the small amount of oil.In this report, the kinetic study of carbon recovery was made using coals with wide size distribution which is suitable for CWM preparation. The flotation method used here is different from the conventional one at the point that collector is fed in the form of gas.Carbon recovery rates for various coals were found to obey the first order kinetics with respect to carbon concentration in the suspension. The rate constants were found to correlate well with the O/C atomic ratio of the coals. Coal concentration of the feed suspension had no effect on the recovery rate when it was smaller than 10%. But at higher concentration, a large decrease of carbon recovery was observed.
Generalized Maximum Entropy for Supervised Classification (2020)

The maximum entropy principle advocates to evaluate events' probabilities using a distribution that maximizes entropy among those that satisfy certain expectations' constraints. Such principle can be generalized for arbitrary decision problems where it corresponds to minimax approaches. This paper establishes a framework for supervised classification based on the generalized maximum entropy principle that leads to minimax risk classifiers (MRCs). We develop learning techniques that determine MRCs for general entropy functions and provide performance guarantees by means of convex optimization. In addition, we describe the relationship of the presented techniques with existing classification methods, and quantify MRCs performance in comparison with the proposed bounds and conventional methods.
Effect of dietary antioxidant-rich foods combined with aerobic training on energy metabolism in healthy young men (2018)

Although supplementation with several antioxidants has been suggested to improve aerobic metabolism during exercise, whether dietary foods containing such antioxidants can exert the metabolic modulation is unclear. This study aimed to investigate the effect of intake of the specific antioxidant-rich foods coupled with exercise training on energy metabolism. Twenty young healthy, untrained men were assigned to antioxidant and control groups: participants in the antioxidant group were encouraged to consume foods containing catechin, astaxanthin, quercetin, glutathione, and anthocyanin. All participants performed cycle training at 60% maximum oxygen consumption for 30 min, 3 days per week for 4 weeks. Maximum work load was significantly increased by training in both groups, while oxygen consumption during exercise was significantly increased in the antioxidant group only. There were positive correlations between maximum work load and fat/carbohydrate oxidations in the antioxidant group. Carbohydrate oxidation during rest was significantly higher in the post-training than that in the pre-training only in the antioxidant group. More decreased levels of serum insulin and HOMA-IR after training were observed in the antioxidant group than in the control group. This study suggests that specific antioxidant-rich foods could modulate training-induced aerobic metabolism of carbohydrate and fat during rest and exercise.
A semantic approach to IE pattern induction (2005)

This paper presents a novel algorithm for the acquisition of Information Extraction patterns. The approach makes the assumption that useful patterns will have similar meanings to those already identified as relevant. Patterns are compared using a variation of the standard vector space model in which information from an ontology is used to capture semantic similarity. Evaluation shows this algorithm performs well when compared with a previously reported document-centric approach.
Cotton Fiber Growth in Planta and in Vitro. Models for Plant Cell Elongation and Cell Wall Biogenesis (2001)

There are only a few cells in the plant kingdom that are as exaggerated in their size or composition as cotton fibers. It is precisely their highly elongated structure and exceptional chemical make-up that establishes cotton fiber as an ideal model for studies of plant cell elongation and cell wall
Reconfigurable digital cartesian feedback for transmitters (2014)

This paper presents an original method to realize digital loop control for a radio communication V/UHF (Very/Ultra High Frequency) transmitter. The objective is to propose a SDR (Software Defined Radio) solution with a correction of the PA (Power Amplifier) nonlinearities. The proposed architecture is full digital solution except the up-converter for specific reasons. The used numeric core is a Virtex6 FPGA (Field Programmable Gate Array). The down-converter and loop filters are integrated in the digital part. Measurements show improvement of 5% of the EVM (Error Vector Magnitude) and more than 20 dB for the ACPR (Adjacent Channel Power Ratio) compared to the open loop. The overall delay system is about 1.4 μs and the loop gain is 20.4 dB.
Propagation of electromagnetic waves in biological media: Refraction at interfaces (2015)

Issues pertaining to modeling of the propagation of electromagnetic waves in a biological medium are considered, including the wave refraction at the biological medium-free space interface. The behavior of the complex dielectric permittivity as a function of the frequency is analytically described. Power losses related to the reflection of waves propagating through an interface between two dielectrics are evaluated with allowance for the dielectric losses in biological media. Based on the results of analysis of the propagation of electromagnetic waves in biological media, it is possible to formulate technical requirements for radiators implanted into a given medium.
A SocioDemographic Analysis of Northeast Atlanta I-85 Peak-Period Commuters Likely to Be Affected by Implementation of Value Pricing Along the Corridor (2010)

In the summer of 2007, data on peak period travelers on Interstate 85 in Metropolitan Atlanta were collected to provide insight on commuter behavior and demographics in preparation for potential value pricing activities to be implemented on the corridor. Over 120,000 license tags of vehicles in both HOV and general purpose lanes were recorded during the field study. 23,000 household locations corresponding to vehicles observed at three sites located along a 16-mile segment of I-85 slated to be a HOV-to-HOT demonstration project were further analyzed in terms of potential travel distance, travel time, and income characteristics. On average, vehicles seen at the field locations traveled at least 10 miles along I-85, much of it within the HOT lane corridor. Additionally, associated households exhibited higher incomes and longer travel times at a representative block group level than did the general population. Data on specific travel time, distance, and income of daily commuters are helpful in assessing a proper pricing structure for tolls along the pilot corridor. Thus, methodology for identifying likely commuters from a field “snapshot” as well as basic pricing guidelines on a per-mile and per-corridor basis is included in this paper.
Automated Pavement Crack Sealing System Development (2011)

Pavement crack sealing operations remain predominantly manual due to the challenges associated with automation. The research performed by the Georgia Tech Research Institute in conjunction with the Georgia Department of Transportation has proved in many ways that a commercial-scale automated crack sealing system is viable. Solutions related to the high-speed firing of nozzles, automated crack detection, and navigation in a real-time system have been demonstrated on a limited-scale system. Additional work remains on the testing of longitudinal crack sealing solutions, and fine tuning of crack detection algorithms. Once these issues have been properly addressed, the remaining tasks will primarily be associated with scaling the system from 12 of width to a full-lane width. The future of automated crack sealing operations is promising as this research has demonstrated that the technical barriers to commercialization have been addressed, thus opening the door for increases in productivity and worker safety.
Reversal of Human Immunodeficiency Virus Type 1 Protein-Induced Inhibition of Natural Killer Cell Activity by Alpha Interferon and Interleukin-2 (2000)

A recombinant fusion peptide, Env-Gag, derived from the human immunodeficiency virus type 1 (HIV-1) genome corresponding to a defined portion of the envelope (Env) and internal core (Gag) proteins was examined for immunoregulatory effects on the cytotoxic activity of natural killer (NK) cell-enriched, large granular lymphocytes (LGL) from healthy donors. Percoll-separated, NK cell-enriched LGL precultured for 24 h with Env-Gag at 10- and 50-ng/ml concentrations, which significantly stimulated lymphocyte proliferation, caused significant suppression of NK cell activity. Denatured Env-Gag did not cause any effect on the NK cell activity of LGL. Two other control peptides, one derived from the Escherichia coli vector used to clone the HIV Env-Gag fusion peptide and the other derived from a non-HIV-1 viral antigen (rubeola virus), did not produce any observable effect on the NK cell activity of LGL, demonstrating the specificity of the effect produced by Env-Gag. Subsequent treatment of LGL with alpha interferon (IFN-alpha) or interleukin 2 (IL-2) alone partially reversed the Env-Gag-induced suppression of NK cell activity. However, LGL treated with both IFN-alpha and IL-2 completely reversed the suppression of NK cell cytotoxicity by Env-Gag. The combined effect of IFN-alpha and IL-2 in enhancing NK cell activity may provide a novel therapeutic approach to the restoration of depressed NK cell activity observed in HIV-infected patients.
Microencapsulation of acetaminophen into poly(L-lactide) by three different emulsion solvent-evaporation methods (2005)

Poly(L-lactide) (PLLA) microcapsules containing acetaminophen (APAP) were prepared by three emulsion solvent-evaporation methods including an O/W-emulsion method, an O/W-emulsion co-solvent method and a W/O/W-multiple-emulsion method. The average size and morphology of the microcapsules varied substantially among these three preparation methods. Various alcohol and alkane co-solvents were found to exert significant impact on the O/W-emulsion co-solvent method and a more lipophilic co-solvent such as heptane appeared to enhance drug encapsulation with an efficiency nearly double of the O/W-emulsion method. When a small amount of water was added as the internal aqueous phase in the W/O/W-multiple-emulsion method, the encapsulation efficiency was found nearly triple of that for the O/W-emulsion method. While having a higher encapsulation efficiency, the microcapsules prepared by the W/O/W-multiple-emulsion method had as good controlled release behaviour as those prepared by the O/W-emulsion method. The release kinetics of microcapsules prepared by the O/W-emulsion method and the O/W-emulsion co-solvent (alcohol) method fitted the Higuchi model well in corroboration with the uniform distribution of APAP in PLLA matrix, i.e. the monolithic type microcapsules. However, the release kinetics of microcapsules prepared by the O/W-emulsion co-solvent (alkane) method and the W/O/W-multiple-emulsion method fitted the first-order model better, indicating the reservoir type microcapsules.
Amidoglycosylation of Polymer-Bound Glycals: A Complete Solid-Phase Synthesis of the Oligosaccharide Domain of the Lewisb Blood Group Determinant (1998)

A new general method for the preparation of N-acetylglucosamine glycosidic linkages has been developed for solid-phase synthesis. The complete pentasaccharide domain of the Lewisb blood group antigen, which is a mediator in the formation of ulcers and gastric cancer, has now been synthesized on solid support (see 1; the shaded circle is the polystyrene support; TIPS=triisopropylsilyl).
Fractional Third and Fourth Dose of RTS,S/AS01 Malaria Candidate Vaccine: A Phase 2a Controlled Human Malaria Parasite Infection and Immunogenicity Study (2016)

NCT01857869.
A Comparative Study of Structurally Related Homogeneous Ruthenium and Iron Catalysts for the Hydrogenation of Levulinic Acid to γ‐Valerolactone (2017)

The conversion of levulinic acid (LA) to γ‐valerolactone (GVL) was investigated by employing the homogeneous Shvo catalyst ( Ru‐1 ) and iron Knölker‐type catalysts, in order to evaluate the possibility to replace ruthenium with cheap, earth‐abundant iron for this catalytic reaction. While the ruthenium‐catalyzed reactions readily proceed, the activating agent required for the iron complex was found to interfere with the LA. This problem could be circumvented by pre‐activating the original Knölker complex ( Fe‐1 ) into the corresponding dicarbonyl mono‐acetonitrile iron species ( Fe‐3 ). The pre‐activated iron catalyst deactivated after a few turn‐overs in transfer hydrogenation reactions with isopropyl alcohol; however, highly improved GVL yields were achieved under H 2 pressure to a notable maximum of 570 turn‐overs for Fe‐3 . Nevertheless, comparative screening experiments with various solvents and kinetic studies showed that Ru‐1 is still superior over Fe‐3 in terms of catalytic activity.
Future mobile phones - complex design challenges from an embedded systems perspective (2002)

In the coming few years, three trends for mobile phones will be seen. First, new communication standards provide packet-switched high-bandwidth wireless communication globally. Second, user applications are going from simple phone administration and text messaging to advanced multimedia and entertainment applications. Finally, because of Internet access and security support, the phones have the potential to move into a financial instrument for economical transactions. The article mainly covers the two former trends, and describes key complexity issues and design challenges. The concept of future mobile phones is described; communication capabilities and some emerging user application capabilities are outlined. The article describes and discusses complexity issues and some design challenges, and also provides a summary. Overall, the focus is from the digital system architecture perspective, and does not cover challenges in the areas of radio, antenna, or analog/digital integration.
Carbo‐Quinoids: Stability and Reversible Redox‐Proaromatic Character towards Carbo‐Benzenes (2015)

Abstract The carbo‐mer of the para‐quinodimethane core is stable within in a bis(9‐fluorenylidene) derivative. Oxidation of this carbo‐quinoid with MnO 2 in the presence of SnCl 2 and ethanol affords the corresponding p‐bis(9‐ethoxy‐fluoren‐9‐yl)‐carbo‐benzene. The latter can be in turn converted back into the carbo‐quinoid by reduction with SnCl 2 , thus evidencing a chemical reversibility of the interconversion between a pro‐aromatic carbo‐quinoid and an aromatic carbo‐benzene, and is reminiscent of the behavior of the benzoquinone/hydroquinone redox couple (in the red–ox opposite sense).
Fault diagnosis on autonomous robotic vehicles with RECOVERY: an integrated heterogeneous-knowledge approach (2002)

The need for embedding fault diagnosis into goal-orientated autonomous robotic vehicles for increased mission robustness is described. The RECOVERY system, a method for increasing the diagnostic capability by integrating commonly available heterogeneous knowledge is presented. Initial real-water results using the Ocean Systems Laboratory's RAUVER vehicle are given.
Longitudinal resonance in surface acoustic phonons (1985)

A detailed study of the longitudinal surface resonance of leaky wave in the acoustic spectrum of solids is carried out. The authors study the lineshape of the resonance in the power spectrum of both isotropic and anisotropic solids. The physical meaning of the new mode is investigated in connection with the reflection coefficients of bulk waves at the free surface and with the amplitude of vibration of Lamb waves.
Abstract 4711: Silencing of miR-221 with anti-microRNA oligonucleotides is an effective therapeutic for hepatocellular carcinoma (2011)

Abstract Patients with advanced hepatocellular carcinoma (HCC) face a dismal prognosis as there are no standardized therapies to treat this stage of the disease. Inhibition of microRNAs that are overexpressed in the tumor with antisense oligonucleotides represents a novel option to treat HCC. For antisense oligonucleotides to be effective, they must reach the target tumor tissue, inhibit the miRNA, modulate the miRNAs target protein levels and prolong survival. We evaluated anti-miR-221 in normal and tumor bearing mice. Of eight different chemistries evaluated, the cholesterol labeled, 2’ O methyl, phosphorothioate modified anti-miR-221 (chol-anti-miR-221) was the most effective at reducing proliferation in vitro. In the absence of transfection reagents, the in vitro proliferation was reduced by the chol-anti-miR-221 but not the scrambled control. Non specific toxicity was observed in vitro for each of the chemically modified scrambled control oligos when transfected with lipid reagent. Chol-anti-miR-221 had improved pharmacokinetics and liver tissue distribution compared to the non cholesterol labeled oligonucleotide in C57Bl/6 mice. Endogenous miR-221 levels in the liver were reduced by chol-anti-miR-221 in C57Bl/6 mice by 90%, 7 days following the start of the dosing schedule. In situ hybridization demonstrated that chol-anti-miR-221 accumulated in the tumor cells of orthotopic mice. Chol-anti-miR-221 reduced endogenous miR-221 levels in the tumors of orthotopic xenograft mice by &amp;gt; 95% and increased p27Kip1 target protein by 3-fold, 7 days after dosing. Chol-anti-miR-221 produced a survival advantage in orthotopic mice compared to those mice treated with a scrambled control oligo (P &amp;lt; 0.05). Our data demonstrate that chol-anti-miR-221 is efficacious in an orthotopic mouse model of HCC and suggests that such a therapy may be beneficial in patients with advanced HCC. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research; 2011 Apr 2-6; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2011;71(8 Suppl):Abstract nr 4711. doi:10.1158/1538-7445.AM2011-4711
Progression-free survival in metastatic, BRAF-mutated colorectal cancer. (2013)

458 Background: BRAF mutations occur in 5-8% of metastatic colorectal cancers and are associated with a significantly worse overall prognosis relative to patients with BRAF wild-type tumors. However, the outcomes with standard chemotherapy of a large cohort of patients with BRAF mutant tumors have not been described. Methods: We searched the MD Anderson Cancer Center databases for colorectal cancer patients with identified BRAF mutations between December 2003 and May 2012. Patients were analyzed for clinical characteristics, progression-free survival, and chemotherapeutic agents used. Survival was estimated according to the Kaplan-Meier method. Results: Among the 1567 patients tested for BRAF mutations at our institution, 127 (8.1%) had tumors with BRAF mutations. The average age was 59.6 years at the time of diagnosis, and 65/127 patients (51.2%) were male. The 71 patients who presented with metastatic disease received a median of 2 lines of chemotherapy. For the first three lines of chemotherapy, median progression-free survival was 5.6 months (n=69 patients), 3.9 months (n=58), and 3.4 months (n=31), respectively. Median PFS was not affected by the backbone chemotherapeutic agent in the first-line setting, whether oxaliplatin-based or irinotecan-based (6.1 months vs. 5.1 months, respectively, p-value = 0.78). Conclusions: Progression-free survival is expectedly poor for patients with BRAF-mutated metastatic colorectal cancer. Despite the ascertainment bias present in this cohort (with testing preferentially performed in patients suitable for clinical trials in refractory disease), fewer than half of patients with metastatic disease received more than 2 lines of therapy. This data not only provides historic controls suitable for future study design in this population but also supports the idea that novel therapeutic options are essential for this group of patients.