gebhart/patrepeval huggingface dataset:
Characterizing MTBE Cometabolism and Propane Metabolism by Mycobacterium austroafricanum JOB5 (2009)

Characterizing MTBE Cometabolism and Propane Metabolism by Mycobacterium austroafricanum JOB5. (Under the direction of Michael R. Hyman.) Cometabolic transformations are unable to support cell growth. This process is often catalyzed by, and superimposed upon, enzyme systems expressed to catalyze carbon- or energy-yielding reactions. Biodegradation of the gasoline additive methyl tertiary butyl ether (MTBE) is known to be superimposed upon a propane-oxidizing system in the aerobic bacterium Mycobacterium austroafricanum (vaccae) JOB5. Taking a whole-cell approach, we investigated the physiology of propane metabolism and MTBE cometabolism in this strain.\n\nMultiple major gasoline components are frequent co-contaminants with MTBE in the environment, and we determined the impacts of these hydrocarbons on the cometabolism of both MTBE and its commonly encountered metabolite, tertiary butyl alcohol (TBA). Most of the hydrocarbons tested supported cell growth and concurrent MTBE and TBA oxidation occurred without affecting final culture optical density. Results suggest hydrocarbon-grown cells simultaneously expressed more than one alkane-oxidizing enzyme system.\n\nNuclear magnetic resonance spectroscopy (NMR) was used to study the pathway of MTBE oxidation in propane-grown cells of strain JOB5. We confirmed the existence of predicted intermediates, including a hemiacetal, formate and formaldehyde. Hydroxyisobutyraldehyde, a predicted intermediate in MTBE oxidation by some bacterial strains was not detected, despite attempts to promote its accumulation. As the pathway of MTBE oxidation progressed, the rate of daughter product oxidation decreased, which may be preventing MTBE-dependent cell growth in strain JOB5.\n\nPropane metabolism was examined using a series of growth experiments and substrate oxidation assays. We observed the simultaneous production, and later consumption of both 1- and 2-propanol during cell growth. This divergent oxidation of propane was apparently followed by the divergent oxidation of propionate and the divergent oxidation of acetone. Our results suggest at least two CO2-fixation steps are involved in propane metabolism in strain JOB5.\n\nFinally, we used NMR to contribute to several studies that characterized the pathway of (i) MTBE oxidation by Nitrosomonas europaea or (ii) bacterial oxidation of a fluorinated analog of TBA. The later study identified a compound that may serve as a tracer for TBA degradation in situ.
Carbon Nanotube Flow Sensors (2003)

We report that the flow of a liquid on single-walled carbon nanotube bundles induces a voltage in the sample along the direction of the flow. The voltage that was produced fit a logarithmic velocity dependence over nearly six decades of velocity. The magnitude of the voltage depended sensitively on the ionic conductivity and on the polar nature of the liquid. Our measurements suggest that the dominant mechanism responsible for this highly nonlinear response involves a direct forcing of the free charge carriers in the nanotubes by the fluctuating Coulombic field of the liquid flowing past the nanotubes. We propose an explanation based on pulsating asymmetric ratchets. Our work highlights the device potential for nanotubes as sensitive flow sensors and for energy conversion.
Employee Capabilities, Workplace Resonance, and Common-Good HRM (2022)

The challenge of economic, social and environmental sustainability is one of the most critical dilemmas facing society on an international scale and therefore needs to be a core priority for organizations. To date, businesses are still struggling to balance a future social-mission with established strategic business goals. This conceptual paper reflects on ambiguity surrounding the societal role and purpose of HRM relating to a range of internal and external dysfunctional relationships. Specifically, we develop further the recently proposed Common-Good HRM (CGHRM) paradigm (Aust, Matthews, Müller-Camen, 2020), and address the lack of an explanatory sociological foundation (Why?), a clearly defined definition (What?), and an operational framework (How?). We draw on two main streams of literature, and enrich Sen’s Capability Approach with Rosa’s Theory of resonance. We thereby reinterpret the challenge of sustainability as a crisis of resonance, and the workplace as a possible enabling zone of resonance. By synergistically defining the role of HRM in terms of a capability-enhancer with a special focus on creating resonant workplace relations and collective opportunities for achievement, we reconnect the individual, collective and institutional levels of analysis and infer a fundamental revaluing of the quality of both workplace social experiences and HRMs relations to the wider world. Finally, adapting Ibrahim’s three-stage model, we describe the process through which HRM can move beyond methodological individualism towards collective sustainable organizational and societal transformation and illustrate our arguments with examples of alternative purpose-driven management approaches who are embracing human, societal and economic change.
Optical and electrical properties of undoped ZnO films grown by spray pyrolysis of zinc nitrate solution (1998)

Undoped ZnO films were deposited by spray pyrolysis using aqueous zinc nitrate solution at different substrate temperatures. The effect of the growth temperature on the structural, optical, electrical, and relaxation properties has been studied. It was found that there was a critical temperature Tc=180 °C below which the thermal decomposition to ZnO did not occur or was incomplete. Films grown above Tc showed strong preferred orientation of polycrystals along the c-axis, while the films grown at Tc or below showed a powder-like, non-oriented polycrystalline structure when they were converted afterwards to zinc oxide by annealing. A slight increase of the optical band gap was observed for as-prepared films as the substrate temperature was decreased near the critical temperature. Annealing brought all the samples to the same band gap 3.30 eV measured at a half height of the maximum absorption. After illumination, the steady-state photoconductivity decayed very slowly with a time constant of about a week for as-grown samples. The steady-state photoconductivity in daylight was very close to saturation. Steady-state photoconductivity in the daylight can be as much as four orders in magnitude larger than the dark value. Annealing in nitrogen at 400 °C brought all samples to the same conductivity of 10−3 (Ω cm)−1 in daylight and 10−4 (Ω cm)−1 in the dark. The photoconductivity transients were complicated and changed from a power law to multiexponential time dependence after annealing. The data are discussed on the basis of model in which hole traps located at the grain boundaries play the major role.
Tuber eburneum and Tuber mujicii: New pine-associated Tuber species from eastern North America (2022)

The ectomycorrhizal truffle genus <i>Tuber</i> is widespread and diverse. Recent sampling of ascomata, ectomycorrhizal root tips, and environmental sequences has resulted in the identification of many <i>Tuber</i> species that cannot be assigned to described species and require formal description. Using morphological and molecular phylogenetic analysis, we describe two North American <i>Tuber</i> species associated with pines (<i>Pinus</i> spp.). <i>Tuber eburneum</i>, sp. nov., is an early-diverging taxon in the Melanosporum clade that differs substantially from all other taxa in that clade due to its light-colored peridium and gleba, lack of peridial warts, and peridial hairs that are ornamented with small, irregular protrusions. <i>Tuber mujicii</i>, sp. nov., is a whitish truffle species in the Puberulum clade. Although <i>T. mujicii</i> is morphologically similar to many related taxa, it can be distinguished by a combination of characters, including peridium color, spore size, number of ascospores per ascus, and number of reticulations across the spore surface.
Deep Eutectic Solvent Assisted Dispersion of Carbon Nanotubes in Water (2020)

Deep Eutectic Solvents (DESs) are emerging as a promising medium for many chemical processes. They can be used to observe specific properties required for nanomaterials' applications. Controlled CO<sub>2</sub> adsorption requires disaggregation of carbon nanotubes into smaller bundles which can be accomplished by dispersing them in aqueous DES system. In this study, response surface methodology (RSM) was adopted to examine the impacts of three important factors on the dispersion of single walled carbon nanotubes (SWNTs) in Choline Chloride-Glycerol (ChCl-Gly) DES; (i) ChCl-Gly (mass% in water), (ii) sonication energy input (J/mL), and (iii) SWNTs' concentration (mg/L). The net negative surface charge of ChCl-Gly, a "green solvent," provided superior dispersion of inherently negatively charged SWNTs in water via electrostatic repulsion. The impacts of the dispersion factors were quantified by the average aggregate diameter (nm) and polydispersity (polydispersity index, PDI) of SWNTs in aqueous-DES systems. Models were developed, experimentally verified, and statistically validated to map the impacts of these factors and to obtain optimized dispersions. The optimized dispersions, characterized by the small (<100 nm) and uniform (<0.1 PDI) SWNTs' aggregates, were achieved at lower sonication energy costs which can have promising implications across many nano-manufacturing fields. The dispersion/aggregation mechanism was proposed using COSMO-RS (based on equilibrium thermodynamics and quantum chemistry) modeling of ChCl-Gly and zeta potential measurements of SWNTs. This understanding will help create optimally sustainable and economically feasible DES-nanomaterial dispersions.
Revisiting the variance-based selection model of diploid drone production for multiple mating in honey bees (2009)

Abstract The high number of mates of honeybee queens has lead to the proposal of several adaptive explanations. The competing hypotheses to explain multiple mating in honeybees and some other social insects have been mostly evaluated empirically with comprehensive theoretical analysis lacking behind. We report on the mathematical analysis of the diploid drone hypothesis for multiple mating, which suggests that multiple mating evolved as a safeguard against the production of infertile male offspring. In accordance with earlier models, our analysis shows that multiple mating does not reduce the average value of diploid drone production but reduces its variance. We combine this observation with a colony growth model to assess the impact of this reduction in variance to the colony fitness. Considering a plausible parameter space for the honeybee, we conclude that the reduction in variance of diploid drone production can be a significant selective force for multiple mating. We have also described rules of a game for which a problem of finding the best strategy is equivalent to the above biological problem of bee mating. We made a significant progress in the general solution of this game and conjectured that the best strategy is strongly related to the geometry of rational numbers.
Tissue-specific differentiation of a circulating CCR9− pDC-like common dendritic cell precursor (2012)

The ontogenic relationship between the common dendritic cell (DC) progenitor (CDP), the committed conventional DC precursor (pre-cDC), and cDC subpopulations in lymphoid and nonlymphoid tissues has been largely unraveled. In contrast, the sequential steps of plasmacytoid DC (pDC) development are less defined, and it is unknown at which developmental stage and location final commitment to the pDC lineage occurs. Here we show that CCR9(-) pDCs from murine BM which enter the circulation and peripheral tissues have a common DC precursor function in vivo in the steady state, in contrast to CCR9(+) pDCs which are terminally differentiated. On adoptive transfer, the fate of CCR9(-) pDC-like precursors is governed by the tissues they enter. In the BM and liver, most transferred CCR9(-) pDC-like precursors differentiate into CCR9(+) pDCs, whereas in peripheral lymphoid organs, lung, and intestine, they additionally give rise to cDCs. CCR9(-) pDC-like precursors which are distinct from pre-cDCs can be generated from the CDP. Thus, CCR9(-) pDC-like cells are novel CDP-derived circulating DC precursors with pDC and cDC potential. Their final differentiation into functionally distinct pDCs and cDCs depends on tissue-specific factors allowing adaptation to local requirements under homeostatic conditions.
Emulsion stability and rigid foams from styrene or divinylbenzene water-in-oil emulsions (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEmulsion stability and rigid foams from styrene or divinylbenzene water-in-oil emulsionsJoel M. Williams, A. James Gray, and Mark H. WilkersonCite this: Langmuir 1990, 6, 2, 437–444Publication Date (Print):February 1, 1990Publication History Published online1 May 2002Published inissue 1 February 1990https://pubs.acs.org/doi/10.1021/la00092a026https://doi.org/10.1021/la00092a026research-articleACS PublicationsRequest reuse permissionsArticle Views1387Altmetric-Citations192LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Design and Optimization of a SiC-Based Versatile Bidirectional High-Voltage Waveform Generator (2022)

Versatile waveform generators are required for multiple load characterization and excitation in a wide variety of industrial and biomedical applications. In the past, these generators have been typically limited in voltage/current/frequency due mainly to limitations of the power devices. However, advances in semiconductor technology have enabled the design of high-performance versatile waveform generators with improved operational ranges. In this paper, to overcome these limitations, a bidirectional multi-level structure is proposed to obtain a versatile waveform generator. To achieve this aim, this paper deals with the design, optimization and experimental validation of a SiC-based bidirectional 13-kVpp versatile large-signal high-frequency arbitrary waveform generator. Unlike previous proposals, the proposed architecture enables bidirectional conversion, being able to deal with reactive and active loads.
Computing median values in a cloud environment using GridBatch and MapReduce (2009)

Traditional enterprise software is built around a dedicated high-performance infrastructure and it cannot map to an infrastructure cloud directly without a significant performance loss. Although MapReduce holds the promise as a viable approach, it lacks building blocks that enable high-performance optimization, especially in a shared infrastructure. Following on our previous work, we introduce another building block called the block level operator (BLO) and we show how it can be applied to solve a real enterprise application of finding the medians in a large data set. We propose two efficient approaches to compute medians, one using MapReduce and the other using the BLO. We compare the two approaches, as well as with that of using the traditional enterprise software stack, and show that our approach using the BLO gives an order of magnitude of improvement.
Abstract 19355: Sequential Shock-No Shock Algorithm to Reduce Interruption During Cardiopulmonary Resuscitation (2016)

Introduction: Pauses in CPR especially those around shocks have been associated with lower likelihood of survival in cardiac arrest. Chest compressions (CC) can induce artifacts that obscure ECG si...
Epistaxis (2019)

Epistaxis is the most common otolaryngologic (ear nose and throat) emergency. Occurring in both children and adults, it is most often minor but may be severe and require acute resuscitation. The rich vascular supply of the nasal cavity predisposes to bleeding. Management requires headlight or endoscopic examination of the nose to identify the site of bleeding and any underlying pathology. Control of bleeding may be by simple chemical cautery or require electrocautery, nasal packing or occlusion of arterial supply by surgery or embolisation. Predisposing factors, such as clotting disorders or hypertension, need to be identified and treated.
Stateology: State-Level Interactive Charting of Language, Feelings, and Values (2016)

People's personality and motivations are manifest in their everyday language usage. With the emergence of social media, ample examples of such usage are procurable. In this paper, we aim to analyze the vocabulary used by close to 200,000 Blogger users in the U.S. with the purpose of geographically portraying various demographic, linguistic, and psychological dimensions at the state level. We give a description of a web-based tool for viewing maps that depict various characteristics of the social media users as derived from this large blog dataset of over two billion words.
Phosphatidylinositol 4,5-Bisphosphate (PIP2)-enhanced G Protein-coupled Receptor Kinase (GRK) Activity: LOCATION, STRUCTURE, AND REGULATION OF THE PIP2 BINDING SITE DISTINGUISHES THE GRK SUBFAMILIES (1996)

The G protein-coupled receptor kinases (GRKs) phosphorylate agonist occupied G protein-coupled receptors and play an important role in mediating receptor desensitization. The localization of these enzymes to their membrane incorporated substrates is required for their efficient function and appears to be a highly regulated process. In this study we demonstrate that phosphatidylinositol 4, 5-bisphosphate (PIP2) enhances GRK5-mediated beta-adrenergic receptor (betaAR) phosphorylation by directly interacting with this enzyme and facilitating its membrane association. GRK5-mediated phosphorylation of a soluble peptide substrate is unaffected by PIP2, suggesting that the PIP2-enhanced receptor kinase activity arises as a consequence of this membrane localization. The lipid binding site of GRK5 exhibits a high degree of specificity and appears to reside in the amino terminus of this enzyme. Mutation of six basic residues at positions 22, 23, 24, 26, 28, and 29 of GRK5 ablates the ability of this kinase to bind PIP2. This region of the GRK5, which has a similar distribution of basic amino acids to the PIP2 binding site of gelsolin, is highly conserved between members of the GRK4 subfamily (GRK4, GRK5, and GRK6). Indeed, all the members of the GRK4 subfamily exhibit PIP2-dependent receptor kinase activity. We have shown previously that the membrane association of betaARK (beta-adrenergic receptor kinase) (GRK2) is mediated, in vitro, by the simultaneous binding of PIP2 and the betagamma subunits of heterotrimeric G proteins to the carboxyl-terminal pleckstrin homology domain of this enzyme (Pitcher, J. A., Touhara, K., Payne, E. S., and Lefkowitz, R. J. (1995) J. Biol. Chem. 270, 11707-11710). Thus, five members of the GRK family bind PIP2, betaARK (GRK2), betaARK2 (GRK3), GRK4, GRK5, and GRK6. However, the structure, location, and regulation of the PIP2 binding site distinguishes the betaARK (GRK2 and GRK3) and GRK4 (GRK4, GRK5, and GRK6) subfamilies.
Sezieren von Atomen: Atombau und Bindung (2013)

Atome zerlegen und neu aufbauen Die Wohnzimmer der Elektronen: Orbitale Dipolmomente von Bindungen und Molekülen Ionenbindung und kovalente Bindung Auf die Mischung kommt es an: Überlappung von Orbitalen Die Darstellung von Orbitalen für organische Moleküle
Mechanism of the Willgerodt Reaction. Studies with 1-Tetralones1 (1957)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMechanism of the Willgerodt Reaction. Studies with 1-Tetralones1WILLIAM G. DAUBEN, RICHARD P. CIULA, and JOHN B. ROGANCite this: J. Org. Chem. 1957, 22, 4, 362–365Publication Date (Print):April 1, 1957Publication History Published online1 May 2002Published inissue 1 April 1957https://pubs.acs.org/doi/10.1021/jo01355a003https://doi.org/10.1021/jo01355a003research-articleACS PublicationsRequest reuse permissionsArticle Views225Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Design and implementation of the automatic generation workflow system (2014)

The traditional web service composition methods always use certain workflow to solve requests which is inflexible and needs a lot of human intervention. To solve this problem, we propose an automatic generation workflow system. This system can generate workflow automatically according to the request provided by the Web service requester. First, construct the field repository, the workflow repository and the Web service repository. Then use automatic generation workflow algorithm to generate the workflow automatically. Classifying the Web service and the workflow according to the field can reduce the semantic ambiguity during the search. Thus, it can improve the precision of the service composition by improving the accuracy of the service discovery.
New Combination of Triamcinolone, 5-Fluorouracil, and Pulsed-Dye Laser for Treatment of Keloid and Hypertrophic Scars (2006)

Overall efficacy of TAC+5-FU was comparable with TAC+5-FU+PDL, but the TAC+5-FU+PDL combination was more acceptable by the patients and produced better results. Its effect on lightening of the lesion was promising. The TAC+5-FU+PDL combination seems to be the best approach for treatment of keloid and hypertrophic scars.
6 Pitfalls in retrospective analysis of data from adjuvant trials (1997)

Section of Dermatologic Oncology, Department of Dermatology, Eberhard-Karls-University, 72076 Tubingen, Germany