gebhart/patrepeval huggingface dataset:
Selective response of Ricinus communis seedlings to soil borne Rhizoctonia infection (2015)

Seedlings of Ricinus communis tolerated soil-borne Rhizoctonia infection in strain dependent manner. There was no connection revealed between pathogenicity of strains and their origin or taxonomic position, however, the castor plant proved to be susceptible to most strains highly pathogenic to other host plants as well. Rhizoctonia zeae (teleomorph: Waitea circinata), a species new for European flora, was less aggressive to R. communis as the most potent R. solani strains. The effect of Rhizoctonia infection on mass accumulation of hypocotyls was more prominent than that on cotyledons. The protein content and glutathione S-transferase (GST) activity increased in parallel with evolution of disease syndrome. Metalaxyl, an acetanilide type systemic anti-oomycete fungicide induced locally the GST activity in R. communis cotyledons with 24 hours lag phase, and this induction was altered in the seedlings grown in Rhizoctonia infested soil by strain dependent manner. It might be concluded, that the stress response related detoxication mechanisms of plants in tolerant host/parasite pairs take effect at higher level than in highly susceptible relationships.
Electron microscope image contrast of small dislocation loops and stacking-fault tetrahedra (1979)

Abstract With the use of the method described in the preceding paper (to be referred to subsequently as I) for constructing the displacement fields, the electron microscope image contrast of small dislocation loops and of stacking-fault tetrahedra has been computed from numerical solutions of the Howie-Whelan (1961) equations. The computer-simulated images, displayed in the form of half-tone pictures, have been used to identify the nature and geometry of such defects in ion-irradiated foils. A systematic study of the contrast of small Frank loops in Cu+ ion irradiated copper under a wide variety of diffraction conditions is reported. In particular the variations of the contrast of loops edge-on and inclined to the electron beam with the operating Bragg reflexion, the thickness and inclination of the foil, depth of the defect in the foil and deviation from the Bragg-reflecting condition have been studied. Methods of obtaining useful information, such as the diameters of the loops, are suggested. The contrast of stacking-fault tetrahedra, and of non-edge perfect dislocation loops in ion-irradiated molybdenum is also investigated.
Review Performance of HV Transmission Line Insulators in Desert Conditions Part I: Review of Research and Methods Adopted Internationally (1983)

Meteorology characterizes desert conditions by a high ambient temperature, frequent high relative humidity, large variation of temperature between night and day, presence of fine suspended sand particles in the air, strong winds, a misty and foggy atmosphere, and a scarcity of rain. These conditions, in the presence of desert contamination, lead to a major operationa problem of HV (high voltage) transmission lines. This paper presents a critical review of the main technical problems related to the performance of insulators in desert polluted areas, summarizing the present state of the ar as regards knowledge of the problems and the methods adopted internationally for their satisfactory solution.
Disenrollment with perfect forward secrecy in threshold schemes (2006)

In this correspondence, we propose a new model for threshold schemes with disenrollment capability (TSDC), to address the scenarios in which the ability of a coalition to construct future shared secrets is prohibited. Compared to existing TSDC models, our model provides forward secrecy by adding a constraint that the broadcast from the dealer is required to activate the reconstruction of any secret. We also present a TSDC model in which the dealer has the enhanced capability of disenrolling any subset of participants, to prevent the otherwise unnecessary rekey of the entire group when a large number of participants are compromised. We establish the lower bounds on the entropy of broadcast messages in both proposed models, as guidelines on constructing broadcast efficient schemes, and present bound achieving schemes.
Asian Journal of Andrology is advancing towards a bright future (2010)

As time quickly passes, we once again have the opportunity to wave goodbye to last year and welcome the New Year. This is also an ideal point at which to reflect on the past and envision a brighter future for Asian Journal of Andrology (AJA).
AC-DC Cuk Converter for Power Quality Improvement of Vector Controlled PMSM Drive (2007)

This paper deals with the analysis, design and digital signal processor (DSP) based hardware implementation of a high frequency isolated AC-DC Cuk converter in discontinuous current mode (DCM) of operation used for power quality improvement at AC mains in vector controlled permanent magnet synchronous motor (PMSM) drive. The design of the Cuk converter is presented to feed the voltage source inverter (VSI) of a vector controlled PMSM drive system. Modeling and simulation is carried out in a standard PSIM software environment. Test results are obtained on DSP based hardware implemented AC-DC Cuk converter fed PMSM drive to demonstrate the improvement in the power quality at AC mains.
TET-catalyzed 5-hydroxymethylcytosine regulates gene expression in differentiating colonocytes and colon cancer (2015)

The formation of differentiated cell types from pluripotent progenitors involves epigenetic regulation of gene expression. DNA hydroxymethylation results from the enzymatic oxidation of 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC) by the ten-eleven translocation (TET) 5-mC dioxygenase enzymes. Previous work has mapped changes in 5-mC during differentiation of intestinal stem cells. However, whether or not 5-hmC regulates colonocyte differentiation is unknown. Here we show that 5-hmC regulates gene expression during colonocyte differentiation and controls gene expression in human colon cancers. Genome-wide profiling of 5-hmC during in vitro colonic differentiation demonstrated that 5-hmC is gained at highly expressed and induced genes and is associated with intestinal transcription factor binding sites, including those for HNF4A and CDX2. TET1 induction occurred during differentiation, and TET1 knockdown altered gene expression and inhibited barrier formation of colonocytes. We find that the 5-hmC distribution in primary human colonocytes parallels the distribution found in differentiated cells in vitro, and that gene-specific 5-hmC changes in human colon cancers are directly correlated with changes in gene expression. Our results support a model in which 5-hmC regulates differentiation of adult human intestine and 5-hmC alterations contribute to the disrupted gene expression in colon cancer.
Molecular Characterization of Radiation-induced Glioblastoma (2018)

Radiation therapy represents an essential pillar of today's cancer treatment and has led to improved survival rates of patients with childhood malignancies including leukemia and central nervous system (CNS) tumors. However, long-term complications such as radiation-induced malignancies can occur in a subset of patients following radiation therapy, especially observed in pediatric patients due to their long follow-up period in case of survival. Radiation-induced glioblastomas (RIGs) have been reported in patients after treatment with cranial irradiation for various primary malignancies such as acute lymphoblastic leukemia (ALL) and medulloblastoma (MB). Histopathologically, most RIGs are best described as high grade gliomas resembling their sporadic counterparts, and histopathologic features to distinguish RIGs from de-novo glioblastoma are lacking.
Electromechanical dynamics of articular cartilage as it undergoes degenerative changes (1983)

Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1983.
Data interface buffer compensation scheme for fast calibration (2017)

Microprocessors and FPGAs need to enable simpler and compact platforms via integration of self-contained test and training circuits, training of data interface buffers for process and temperature variation being a prime example. This paper studies package embedding of resistors for buffer tuning and presents a scheme to utilize a single resistor to train a large number of buffers without increase in latency. Using SNR analysis, transient noise simulations and the consequent filtering latencies it is shown that embedding the compensation resistor on the package reduces the calibration time by 5µs while also reducing the filter size by a factor of 10.
The Common Cold: Control? (1984)

Journal Article The Common Cold: Control? Get access Robert B. Couch Robert B. Couch Department of Microbiology and Immunology, Baylor College of Medicine, Houston, Texas Search for other works by this author on: Oxford Academic PubMed Google Scholar The Journal of Infectious Diseases, Volume 150, Issue 2, August 1984, Pages 167–173, https://doi.org/10.1093/infdis/150.2.167 Published: 01 August 1984
Whole-genome analysis for effective clinical diagnosis and gene discovery in early infantile epileptic encephalopathy (2018)

Early infantile epileptic encephalopathy (EIEE) is a devastating epilepsy syndrome with onset in the first months of life. Although mutations in more than 50 different genes are known to cause EIEE, current diagnostic yields with gene panel tests or whole-exome sequencing are below 60%. We applied whole-genome analysis (WGA) consisting of whole-genome sequencing and comprehensive variant discovery approaches to a cohort of 14 EIEE subjects for whom prior genetic tests had not yielded a diagnosis. We identified both de novo point and INDEL mutations and de novo structural rearrangements in known EIEE genes, as well as mutations in genes not previously associated with EIEE. The detection of a pathogenic or likely pathogenic mutation in all 14 subjects demonstrates the utility of WGA to reduce the time and costs of clinical diagnosis of EIEE. While exome sequencing may have detected 12 of the 14 causal mutations, 3 of the 12 patients received non-diagnostic exome panel tests prior to genome sequencing. Thus, given the continued decline of sequencing costs, our results support the use of WGA with comprehensive variant discovery as an efficient strategy for the clinical diagnosis of EIEE and other genetic conditions.
Tyrosine-phosphorylated Stat1 and Stat2 plus a 48-kDa protein all contact DNA in forming interferon-stimulated-gene factor 3. (1995)

Interferon alpha induction of transcription operates through interferon-stimulated-gene factor 3 (ISGF), a transcription factor two components of which are members of the newly characterized Stat family of transcription factors. Interferon alpha induces tyrosine phosphorylation of Stat1 and Stat2 proteins that associate and, together with a 48-kDa protein, form ISGF3. Evidence is presented that a heterodimer of Stat1 and Stat2 is present in ISGF3 and that Stat1 and the 48-kDa protein make precise contact, while Stat2 makes general contact, with the interferon-stimulated response element, the binding site of the ISGF3.
Bovine CCL28 Mediates Chemotaxis via CCR10 and Demonstrates Direct Antimicrobial Activity against Mastitis Causing Bacteria (2015)

In addition to the well characterized function of chemokines in mediating the homing and accumulation of leukocytes to tissues, some chemokines also exhibit potent antimicrobial activity. Little is known of the potential role of chemokines in bovine mammary gland health and disease. The chemokine CCL28 has previously been shown to play a key role in the homing and accumulation of IgA antibody secreting cells to the lactating murine mammary gland. CCL28 has also been shown to act as an antimicrobial peptide with activity demonstrated against a wide range of pathogens including bacteria, fungi and protozoans. Here we describe the cloning and function of bovine CCL28 and document the concentration of this chemokine in bovine milk. Bovine CCL28 was shown to mediate cellular chemotaxis via the CCR10 chemokine receptor and exhibited antimicrobial activity against a variety of bovine mastitis causing organisms. The concentration of bovine CCL28 in milk was found to be highly correlated with the lactation cycle. Highest concentrations of CCL28 were observed soon after parturition, with levels decreasing over time. These results suggest a potential role for CCL28 in the prevention/resolution of bovine mastitis.
A new method for measuring the spectral emissivity of heated bodies (2020)

Abstract A new spectral method for measuring the emissivity of solids at high temperatures is considered. The method is based on a linear dependence of the spectral energy brightness of a body on wavelength in a narrow spectral range. The theoretical basis and the results of experimental verification of the method are presented.
Volatile metabolites fingerprinting to discriminate the major post harvest diseases of mango caused by Colletotrichum gloeosporioides Penz. and Lasiodiplodia theobromae Pat. (2017)

Volatile metabolites emitted from mango fruits artificially inoculated with two toxigenic fungi isolated from infected mangoes were profiled using gas chromatography/mass spectrometry. A noteworthy differential expression of volatile metabolites was observed. The chromatographic profiling study afforded a total of 88 different volatile compounds. Healthy uninjured mango fruits yielded 10 metabolites as a standard and uninoculated injured mango fruit emitted 23 compounds. Mango fruits inoculated with Colletotrichum gloeosporioides yielded 29 volatile metabolites; while that inoculated with Lasiodiplodia theobromae Pat. yielded 26 different volatile metabolites. Among them only 3 volatile compounds (2,6 ,10-trimethyltetradeca ne, crocetane and phellandrene) found consistently in fruits inoculated with C. gloeosporioides and L. theobromae. Whereas, 2-propylmalonic acid, 1,4 cyclohexadiene, 1-methyl-, boronic acid, cyclohexyl dimethoxymethyl, Acetic acid, methyl ester, and T hujol was common in fruits inoculated with C. gloeosporioides while fruits inoculated with L. theobromae had specific volatiles 1,3-dimethoxy-2-(methoxymethyl)-2 -methylpropa ne, Oxalic a cid, cyclohexyldecyl ester, Cyclopentanepropionic acid, 2,5-cyclohexadiene-1,4-dione, 2,6-bis(1,1-dimethylethyl)-, Carbonic acid, octadecyl phenyl ester, Spiro-1-(cyclohex-2-ene)-2'-(5'-oxabicyclopentane), 1',4',2,6,6pentamethyl-and stearic acid. This study suggests that these unique metabolites can be used as biomarkers to detect postharvest diseases or toxigenic fungal pathogens of mango at an early stage of disease progression and to successfully device strategies to protect the fruits.
Immunologic release of beta-hexosaminidase and beta-glucuronidase from purified rat serosal mast cells. (1979)

The acid exoglycosidases β-hexosaminidase and β-glucuronidase are present in rat serosal mast cells at concentrations of 1.2 ± 0.5 units and 0.24 ± 0.11 units/106 cells, respectively, and are released in a dose- and time-dependent fashion in response to immunologic challenge with rabbit anti-rat F(ab′)2. The sum of the released and residual β-hexosaminidase and β-glucuronidase was no different from that of resting unchallenged cells, thereby indicating that release in physiologic buffer was sufficient for complete bioavailability of the secreted enzymes when assessed with small synthetic substrates. A comparison of the release of the acid exoglycosidases with that of histamine yields regression lines that have correlation coefficients of ≥ 0.97 for each enzyme and that intersect at the point of origin, suggesting absence of a threshold effect on the release of these mediators. The slopes of these regression lines indicate that at least 86 and 65% of the cellular content of β-hexosaminidase and of β-glucuronidase, respectively, are available for immunologic release and are therefore localized in mast cell secretory granules. The predominant isomeric form of β-hexosaminidase in the rat mast cell, as indicated by its chromatographic behavior, is type A and the A isomer is the predominant form released on immunologic activation of the cells. The only isomeric form of β-glucuronidase identified in rat serosal mast cells based upon its electrophoretic mobility is the lysosomal form, and this form was the only one released after immunologic activation of these cells. The mast cell secretory granule, based upon its content of acid hydrolases and its capacity to form phagolysosomes, is considered a modified lysosome, which also contains novel chemical mediators not generally observed in lysosomes of other cells.
WISE 2005: flow and nitroglycerin mediated dilation following 56 days of head down tilt bed rest with and without an exercise countermeasure. (2007)

This investigation set out to determine the effect of 56 days of head-down tilt bed rest (HDBR) and an exercise countermeasure on endothelial dependent and independent vascular function. 24women took part in this study. 8 subjects completed lower body resistance and aerobic exercise (EX, treadmill running 3-4 days per week for 40-min followed by 10-min of static LBNP, and resistive exercise on a flywheel device every 3rd day) and 16 subjects were considered as non-exercisers in a control group and a protein supplement group. FMD was induced by release of distal limb ischemia and NMD by sublingual administration of 0.3 mg of nitroglycerin before and after HDBR. Preliminary results of this study suggest that HDBR without EX results in a decreased resting diameter of the popliteal while EX increased the diameter. It is also suggested that FMD was elevated without exercise in both brachial and popliteal arteries, while pre-HDBR FMD was preserved by EX in the popliteal, but not the brachial artery. NMD appears to be elevated in the popliteal and femoral in the absence of exercise, but unchanged in the brachial artery or at any site for EX.
Unsupervised Sentence Simplification via Dependency Parsing (2022)

Text simplification is the task of rewriting a text so that it is readable and easily understood. In this paper, we propose a simple yet novel unsupervised sentence simplification system that harnesses parsing structures together with sentence embeddings to produce linguistically effective simplifications. This means our model is capable of introducing substantial modifications to simplify a sentence while maintaining its original semantics and adequate fluency. We establish the unsupervised state-of-the-art at 39.13 SARI on TurkCorpus set and perform competitively against supervised baselines on various quality metrics. Furthermore, we demonstrate our framework's extensibility to other languages via a proof-of-concept on Vietnamese data. Code for reproduction is published at \url{https://github.com/isVy08/USDP}.
Cooperative and opportunistic transmission for wireless ad hoc networks (2007)

Moving toward 4G, wireless ad hoc networks receive growing interest due to users' provisioning of mobility, usability of services, and seamless communications. In ad hoc networks fading environments provide the opportunity to exploit variations in channel conditions, and transmit to the user with the currently "best" channel. In this article two types of opportunistic transmission, which leverage time diversity and multi-user diversity, respectively, are studied. Considering the co-channel interference and lack of a central controller in ad hoc networks, the "cooperative and opportunistic transmission" concept is promoted. For opportunistic transmission that exploits time diversity, it is observed that the inequality in channel contention due to the hidden terminal phenomenon tends to result in energy inefficiency. Under this design philosophy, we propose a distributed cooperative rate adaptation (CRA) scheme to reduce overall system power consumption. Taking advantage of the time-varying channel among different users/receivers and being aware of the potential contention among neighboring transmissions, we propose a QoS-aware cooperative and opportunistic scheduling (COS) scheme to improve system performance while satisfying QoS requirements of individual flows. Simulation results show that by leveraging node cooperation, our proposed schemes, CRA and COS, achieve higher network throughput and provide better QoS support than existing work
HUMAN AND PLANT FLAVIN-CONTAINING MONOOXYGENASEN-OXYGENATION OF AMINES: DETOXICATION VS. BIOACTIVATION (2002)

Generally, the flavin-containing monooxygenase of mammalian systems has been considered a detoxication enzyme converting nucleophilic heteroatom-containing chemicals into polar, more readily excreted metabolites. The beneficial effects of this process are thought to be participation in the detoxication of foodstuffs and other xenobiotics that might otherwise be bioactivated by other enzyme systems. The physiological role of mammalian FMO is unknown although it has been observed that many heteroatom-containing chemicals in plants are efficiently oxygenated by FMO. Recently, a plant FMO-like enzyme has been characterized and it appears to possess many of the same functional properties of mammalian FMO. The advantage of studying the FMO-like genes and enzymes in Arabidopsis as a model system allows for the investigation of the role of FMO-like enzymes in plant growth and development. The Arabidopsis FMO-like gene product, while resembling the mammalian counterpart in many respects, is quite distinct. However, study of the Arabidopsis FMO-like enzyme may provide considerable insight into the possible role of mammalian FMOs in biogenic amine metabolism.
A 45nm 1Mb embedded STT-MRAM with design techniques to minimize read-disturbance (2011)

1Mb embedded STT-MRAM macro using 45nm CMOS process includes two key design features; a dual-voltage row decoder with a charge sharing scheme for read operations and a sensing circuit with two equalizers and read-disturbance-free reference cells. These designs minimize read-disturbance and achieve fast read operation.
Stable explicit depth extrapolation of seismic wavefields (1991)

Abstract Stability has traditionally been one of the most compelling advantages of implicit methods for seismic wavefield extrapolation. The common 45-degree, finite-difference migration algorithm, for example, is based on an implicit wavefield extrapolation that is guaranteed to be stable. Specifically, wavefield energy will not grow exponentially with depth as the wavefield is extrapolated downwards into the subsurface. Explicit methods, in contrast, tend to be unstable. Without special care in their implementation, explicit extrapolation methods cause wavefield energy to grow exponentially with depth, contrary to physical expectations.The Taylor series method may be used to design finite-length, explicit, extrapolation filters. In the usual Taylor series method, N coefficients of a finite-length filter are chosen to match N terms in a truncated Taylor series approximation of the desired filter's Fourier transform. Unfortunately, this method yields unstable extrapolation filters. However, a simple modification of the Taylor series method yields extrapolators that are stable.The accuracy of stable explicit extrapolators is determined by their length--longer extrapolators yield accurate extrapolation for a wider range of propagation angles than do shorter filters. Because a very long extrapolator is required to extrapolate waves propagating at angles approaching 90 degrees, stable explicit extrapolators may be less efficient than implicit extrapolators for high propagation angles. For more modest propagation angles of 50 degrees of less, stable explicit extrapolators are likely to be more efficient than current implicit extrapolators. Furthermore, unlike implicit extrapolators, stable explicit extrapolators naturally attenuate waves propagating at high angles for which the extrapolators are inaccurate.