gebhart/patrepeval huggingface dataset:
Re-usable self-poled piezoelectric/piezocatalytic films with exceptional energy harvesting and water remediation capability (2020)

The need for sustainable technologies to address environmental pollution and energy crisis is paramount. Here we present a novel multifunctional nanocomposite, free standing film by combining piezoelectric molybdenum sulphide (MoS<sub>2</sub>) nanoflower with poly vinylidene fluoride (PVDF) polymer, which can harness otherwise wasted mechanical energy for useful energy generation and/or water purification. The unique MoS<sub>2</sub> nanoflower morphology is exploited to render the whole nanocomposite piezo active. A number of features are demonstrated to establish potential practical usage. Firstly, the nanocomposite is piezoelectric and piezocatalytic simultaneously without requiring any poling step (i.e. self-poled). Secondly, the self-poled piezoelectricity is exploited to make a nanogenerator. The nanogenerator produced >80 V under human finger tapping with a remarkable power density, reaching 47.14 mW cm<sup>-3</sup>. The nanocomposite film is made by simple solution casting, and the corresponding nanogenerator powers up 25 commercial LEDs by finger tapping. Last but not the least, the developed films show efficient, fast and stable piezocatalytic dye degradation efficiency (>90% within 20 min) against four different toxic and carcinogenic dyes under dark condition. Reusability of at least 10 times is also demonstrated without any loss of catalytic activity. Overall, our nanocomposite has clear potential for use as self-powered sensor and energy harvester, and in water remediation systems. It should potentially also be deployable as a surface mounted film/coating in process engineering, industrial effluent management and healthcare devices systems.
Laboratory transmission of semliki forest virus by Aedes togoi theo (1960)

Laboratory transmission of semliki forest virus by Aedes togoi theo E.R. Nye, E.R. Nye Department of Entomology, London School of Hygiene and Tropical Medicine UK Search for other works by this author on: Oxford Academic PubMed Google Scholar J.C. Lien J.C. Lien Department of Entomology, London School of Hygiene and Tropical Medicine UK Search for other works by this author on: Oxford Academic PubMed Google Scholar Transactions of The Royal Society of Tropical Medicine and Hygiene, Volume 54, Issue 3, May 1960, Pages 263–264, https://doi.org/10.1016/0035-9203(60)90072-9 Published: 01 May 1960
LONG-TERM PERFORMANCE OF REINSTATED TRENCHES AND THEIR ADJACENT PAVEMENTS. PART 2: LONG-TERM PERFORMANCE OF REINSTATEMENTS IN THE HIGHWAY (2003)

The report is the result of a study, commissioned by the Department for Transport (DfT) and the CSS, which was carried out by TRL Limited. It is based on earlier research work undertaken on a number of individual reinstatement sites (168 in total) and two major trial sites which were trenched and reinstated according to the NRSWA Specification (HMSO, 1992 - First Edition). As part of the study, the 168 sites and the major trial sites were re-visited to assess their longer-term performance and to determine whether the condition of the adjacent highway had deteriorated to such an extent that premature maintenance was required to both the reinstatement and the adjacent pavements. At the major trial sites, measurements of deflection were made using a Deflectograph and a Falling Weight Deflectometer (FWD). Rut depths and transverse profiles were measured using the TRL Transverse Profilometer (TP) and the Highways Agency's Routine Road Investigation System (HARRIS) as well as a visual assessment of the surface condition of the reinstatements and surrounding pavements. Results from the two major trial sites indicate that, when reinstatements are carried out in accordance with the Specification, the long-term structural performance of a carriageway is likely to remain comparable with that present prior to the works, at least during the HAUC guarantee period and up to six years beyond this. Nonetheless, the visual condition results indicate some tendency towards potential structural failure of the pavements in the longer term. In the case of the 168 individual reinstatement sites, evidence suggests that, the 'service lives' of carriageways and footways containing reinstatements were reduced. However, the magnitude and severity of this reduction has not been fully quantified by this study because of the paucity of data relating to remedial treatment for some sites. Results of deflection testing using the FWD indicated that the zone immediately adjacent to a trench generally tended to be weaker than the original pavement remote from the trench. The structural and environmental impacts of reinstated multiple-openings have not been considered as none of the sites contained these features. (A)
Research on identifying drainage pipeline blockage based on multi-feature fusion (2017)

In order to solve the difficulties of detecting partial blockage in urban drainage pipeline and to determine the degree of blocking, a novel method based on multi-feature fusion technique of recognizing pipe blockage is proposed in this paper. Firstly, the acoustic response signal collected from a section of working sewer pipe is decomposed by 3 levels wavelet packet decomposition, and the high-energy wavelet packet nodes are selected to reconstruct the signal to establish feature components. Then the characteristics of wavelet energy entropy, approximate entropy and fractal box dimension of the feature components are extracted respectively, so that the classification feature sets can be constructed. Finally, the particle swarm optimization algorithm is used to optimize the parameters of the SVM classifier to identify the blockage fault signal. The results from the experiments have shown that the method can not only effectively identify the different degrees of blocking failure, but also eliminate the impact of the lateral connection from fault identification. As a result, the accuracy rate of pipeline blockage identification is improved, and the method also provided a research foundation for early fault detection of working pipeline.
Maternal morbidity and mortality associated with multiple gestations (2000)

Multiple gestation increases the risk of significant maternal morbidity and mortality.
Molecular markers in Paget disease of the breast (2001)

Tumors from patients with Paget disease of the breast were positive for c-erbB-2, Cyclin D1, and Ki-67, molecular markers commonly associated with more aggressive tumor behavior and poorer survival in breast cancer patients. Few of these tumors expressed Bcl-2 or ER and PR, which are generally associated with a better prognosis. Similar expression of these markers in both Paget cells and the underlying carcinoma supports the theory that these cells are the result of an intraepidermal spread of ductal carcinoma.
Genomic rearrangements in theCFTRgene: Extensive allelic heterogeneity and diverse mutational mechanisms (2004)

Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator gene (CFTR/ABCC7). Despite the extensive and enduring efforts of many CF researchers over the past 14 years, up to 30% of disease alleles still remain to be identified in some populations. It has long been suggested that gross genomic rearrangements could account for these unidentified alleles. To date, however, only a few large deletions have been found in the CFTR gene and only three have been fully characterized. Here, we report the first systematic screening of the 27 exons of the CFTR gene for large genomic rearrangements, by means of the quantitative multiplex PCR of short fluorescent fragments (QMPSF). A well-characterized cohort of 39 classical CF patients carrying at least one unidentified allele (after extensive and complete screening of the CFTR gene by both denaturing gradient gel electrophoresis and denaturing high-performance liquid chromatography) participated in this study. Using QMPSF, some 16% of the previously unidentified CF mutant alleles were identified and characterized, including five novel mutations (one large deletion and four indels). The breakpoints of these five mutations were precisely determined, enabling us to explore the underlying mechanisms of mutagenesis. Although non-homologous recombination may be invoked to explain all five complex lesions, each mutation appears to have arisen through a different mechanism. One of the indels was highly unusual in that it involved the insertion of a short 41 bp sequence with partial homology to a retrotranspositionally-competent LINE-1 element. The insertion of this ultra-short LINE-1 element (dubbed a "hyphen element") may constitute a novel type of mutation associated with human genetic disease.
Models of heme d1. Molecular structure and NMR characterization of an iron(III) dioxoisobacteriochlorin (porphyrindione) (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTModels of heme d1. Molecular structure and NMR characterization of an iron(III) dioxoisobacteriochlorin (porphyrindione)K. M. Barkigia, C. K. Chang, J. Fajer, and M. W. RennerCite this: J. Am. Chem. Soc. 1992, 114, 5, 1701–1707Publication Date (Print):February 1, 1992Publication History Published online1 May 2002Published inissue 1 February 1992https://pubs.acs.org/doi/10.1021/ja00031a025https://doi.org/10.1021/ja00031a025research-articleACS PublicationsRequest reuse permissionsArticle Views140Altmetric-Citations43LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Perfil de aprendizaje del estudiante de precálculo de la Universidad de los Andes (2024)

Cerebellum-brainstem strokes are less frequently cardioembolic, have a less severe presentation, and carry a better immediate and long-term prognosis.
Reactions of Methyl Diazoacetate with (E)‐ and (Z)‐1,2‐Bis(trifluoromethyl)ethene‐1,2‐dicarbonitrile: Novel and Unanticipated Pathways (2007)

Abstract The cycloadditions of methyl diazoacetate to 2,3‐bis(trifluoromethyl)fumaronitrile (( E )‐ BTE ) and 2,3‐bis(trifluoromethyl)maleonitrile (( Z )‐ BTE ) furnish the 4,5‐dihydro‐1 H ‐pyrazoles 13 . The retention of dipolarophile configuration proceeds for ( E )‐ BTE with &gt; 99.93% and for ( Z )‐ BTE with &gt; 99.8% (CDCl 3 , 25°), suggesting concertedness. Base catalysis (1,4‐diazabicyclo[2.2.2]octane (DABCO), proton sponge) converts the cycloadducts, trans ‐ 13 and cis ‐ 13 , to a 94 : 6 equilibrium mixture (CDCl 3 , r.t.); the first step is N ‐deprotonation, since reaction with methyl fluorosulfonate affords the 4,5‐dihydro‐1‐methyl‐1 H ‐pyrazoles. Competing with the cis / trans isomerization of 13 is the formation of a bis(dehydrofluoro) dimer (two diastereoisomers), the structure of which was elucidated by IR, 19 F‐NMR, and 13 C‐NMR spectroscopy. The reaction slows when DABCO is bound by HF, but F − as base keeps the conversion to 22 going and binds HF. The diazo group in 22 suggests a common intermediate for cis / trans isomerization of 13 and conversion to 22 : reversible ring opening of N ‐deprotonated 13 provides 18 , a derivative of methyl diazoacetate with a carbanionic substituent. Mechanistic comparison with the reaction of diazomethane and dimethyl 2,3‐dicyanofumarate, a related tetra‐acceptor‐ethylene, brings to light unanticipated divergencies.
UV Resistance of Bacillus anthracis Spores Revisited: Validation of Bacillus subtilis Spores as UV Surrogates for Spores of B. anthracis Sterne (2003)

Recent bioterrorism concerns have prompted renewed efforts towards understanding the biology of bacterial spore resistance to radiation with a special emphasis on the spores of Bacillus anthracis. A review of the literature revealed that B. anthracis Sterne spores may be three to four times more resistant to 254-nm-wavelength UV than are spores of commonly used indicator strains of Bacillus subtilis. To test this notion, B. anthracis Sterne spores were purified and their UV inactivation kinetics were determined in parallel with those of the spores of two indicator strains of B. subtilis, strains WN624 and ATCC 6633. When prepared and assayed under identical conditions, the spores of all three strains exhibited essentially identical UV inactivation kinetics. The data indicate that standard UV treatments that are effective against B. subtilis spores are likely also sufficient to inactivate B. anthracis spores and that the spores of standard B. subtilis strains could reliably be used as a biodosimetry model for the UV inactivation of B. anthracis spores.
The Effects of Lipophilic Antioxidants on the Affinity of LDL to Its Receptor: A Model for Prevention of Atherogenesis (2002)

The affinity of low density lipoprotein (LDL) to its receptor is very important, because most of LDL uptake pathway is done by the LDL receptor and the change in size of LDL particle and the modification in its components may affects the LDL affinity for its recept or. In this study, the effects of lipophilic agents such as vitamin E and seven volatile oils: anethol, eugenol, geraniol, limonene, linalool, pulegone and thymol have been investigated on the affinity of LDL to its receptor. LDL receptor was purified of bovine adrenal tissue. LDL was isolated by sequential density ultracentrifugation from normolipidemic human plasma. Then, LDL was labeled with fluoresein isothiocyanate (FITC) at 4°C for 24 h. Native LDL was incubated with various concentrations of each of the volatile oils and vitamin E for 2 h. Finally, the native LDL treated with volatile oils and vitamin E was incubatd with the LDL receptor in the presence of labeled -LDL at 37°C for 30 min. After incubation, the medium was centrifuged at 4000 ×g for 20 min and the fluorescence intensity (FI) of supernatant from each sample was determined at excitation 495 nm and emission 515 nm. The elevation of FI in each fraction demonstrates increasing the affinity of non -labeled-LDL to its receptor. We showed that vitamin E and volatile oils increased the affinity of LDL to its receptor, and among these compounds, vitamin E and thymol are the best agents that increase the affinity of native LDL to its receptor. The effects of these compounds are as follows: vitamin E > thymol > eugenol > anethol > geraniol > linalool > limonene > pulegone. These findings raise the possibility that vitamin E and some of the volatile oils may decrease the effect of LDL in formation of atherosclerotic lesions. Iran. Biomed. J. 6 (4): 111-115, 2002
Formation and Catalytic Activity of Pd Nanoparticles on Silica in Supercritical CO2. (2007)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Monolithic integration of an AlGaAs/GaAs DH LED with a GaAs FET driver (1982)

An AlGaAs/GaAs double heterostructure light emitting diode (LED) and a GaAs field effect transistor (FET) have been monolithically integrated on a GaAs substrate using a combination of liquid phase and molecular beam epitaxies. The electrical isolation between LED and FET has been achieved by inserting a molecular beam-grown high resistivity AlGaAs layer. A linear gate voltage-to-light power transfer characteristic with a 13 ns time constant has been demonstrated.
The music information retrieval evaluation exchange (2005-2007): A window into music information retrieval research (2008)

The Music Information Retrieval Evaluation eXchange (MIREX) is the community-based framework for the formal evaluation of Music Information Retrieval (MIR) systems and algorithms. By looking at the background, structure, challenges, and contributions of MIREX this paper provides some insights into the world of MIR research. Because MIREX tasks are defined by the community they reflect the interests, techniques, and research paradigms of the community as a whole. Both MIREX and MIR have a strong bias toward audio-based approaches as most MIR researchers have strengths in signal processing. Spectral-based approaches to MIR tasks have led to advancements in the MIR field but they now appear to be reaching their limits of effectiveness. This limitation is called the “glass ceiling” problem and the MIREX results data support its existence. The post-hoc analyses of MIREX results data indicate that there are groups of systems that perform equally well within various MIR tasks. There are many challenges facing MIREX and MIR research most of which have their root causes in the intellectual property issues surrounding music. The current inability of researchers to test their approaches against the MIREX test collections outside the annual MIREX cycle is hindering the rapid development of improved MIR systems.
Photochemistry of β-diketones (1965)

R. C. Cookson, A. G. Edwards, J. Hudec and M. Kingsland, Chem. Commun. (London), 1965, 98 DOI: 10.1039/C19650000098
Post-reconstitution Stability of Telavancin with Commonly Used Diluents and Intravenous Infusion Solutions (2015)

These results are supportive of a total hold time for reconstituted telavancin in vials plus the time in IV infusion solutions in polyvinyl chloride bags to not exceed 12 hours under ambient conditions and 7 days under refrigeration.
3 Vectors Game and Balance Multicast architecture Algorithms for Sensor Grid (2011)

We propose a scheme to reach shorter multicast delay, better energy utilizing efficiency and higher efficiency of data transferring for Sensor Grid. Our scheme calculates the space, energy and data weight vectors in one cluster. Then it searches a new vector composed by the linear combination of the three individual ones. We build game balance equation, use the equal correlation coefficient between the new and old vectors to find the point of game balance, seek linear parameters, and generate a least weight path tree. Extended simulation results indicate that our scheme attains less average multicast delay, the number of links used and better system robusticity.
Purification and Properties of a Plasma Membrane H+-ATPase from the Extremely Acidophilic Alga Dunaliella acidophila (1993)

This paper describes partial purification and characterization of a vanadate-sensitive H+-ATPase from plasma membranes of Dunaliella acidophila, an extremely acidophilic unicellular alga (I. Sekler, H.U. Glaser, U. Pick [1991] J Membr Biol 121: 51-57). Purification is based on the insolubility in and stability of the enzyme in Triton X-100. The purified enzyme is highly enriched in a polypeptide of molecular mass 100 kD, which cross-reacts with antibodies against the plant plasma membrane H+-ATPase. Upon reconstitution into proteoliposomes, the enzyme catalyzes an ATP-dependent electrogenic H+ uptake. ATP hydrolysis is stimulated by lipids, is inhibited by vanadate, diethylstilbestrol, dicyclohexylcarbodiimide, erythrosine, and mercurials, and shows a sharp optimum at pH 6. Unusual properties of this enzyme, by comparison with plant plasma membrane H+-ATPases, are a higher affinity for ATP (Km = 40 [mu]M) and a larger stimulation by K+, which interacts with the enzyme from its cytoplasmic side. Comparative studies with cross-reacting antibodies, prepared against different domains of the plant H+-ATPase, suggest that the central hydrophilic domain containing the catalytic site is more conserved than the C- and N-terminal ends. The high abundance and stability of the plasma membrane H+-ATPase from D. acidophila make it an attractive model system for studies of the structure-function relations and regulation of this crucial enzyme.
Risk factors for recurrence in stage II/III colorectal cancer patients treated with curative surgery: The impact of postoperative tumor markers and an infiltrative growth pattern (2016)

High-recurrence risk can be identified in stage II/III CRC patients by assessing perioperative serum tumor marker levels, lymphatic invasion, and infiltrative growth patterns. Intensive follow-up for patients with these risk factors may help detect recurrences promptly and improve survival. J. Surg. Oncol. 2016;114:368-374. © 2016 Wiley Periodicals, Inc.
High prevalence of the C634Y mutation in the RET proto-oncogene in MEN 2A families in Spain (1999)

The RET proto-oncogene encodes a receptor tyrosine kinase expressed in neural crest derived tissues. Germline mutations in the RET proto-oncogene are responsible for three different dominantly inherited cancer syndromes: multiple endocrine neoplasia type 2A (MEN 2A), type 2B (MEN 2B), and familial medullary thyroid carcinoma (FMTC). MTC can also occur sporadically. Molecular characterisation of the RET proto-oncogene has been performed by PCR-SSCP analysis, direct DNA sequencing, and restriction enzyme analysis in 49 unrelated, Spanish, MEN 2 families: 30 MEN 2A families, six FMTC families, and 13 families classified as "other". Germline missense mutations in one of six cysteine codons (609, 611, 618, and 620 in exon 10, and codons 630 and 634 in exon 11), which encode part of the extracellular cysteine rich domain of RET, have been detected in the majority of these families: 100% of MEN 2A families, 67% of FMTC families, and 54% of families classified as "other". No RET mutations in exons 10, 11, 13, 14, 15, or 16 were detected in the remaining families. The most frequent RET mutation in MEN 2A Spanish families is C634Y, occurring in 73% of cases. Haplotype analysis does not exclude the possibility of founder effects in Spanish MEN 2A families with the C634Y mutation.
A role for GPI-CD59 in promoting T-cell signal transduction via LAT (2018)

Cluster of differentiation 59 (CD59) is a glycosylphosphatidylinositol-anchored protein. Cross-linking of CD59 with specific monoclonal antibodies can cause a series of intracellular signal transduction events. However, the underlying molecular mechanisms are poorly understood. Linker for activation of T-cells (LAT) is a crucial adaptor protein in T-cell signaling, and its phosphorylation and palmitoylation are essential for its localization and function. In a previous study by the present authors, it was demonstrated that CD59 may be responsible for LAT palmitoylation, thereby regulating T-cell signal transduction. The present study detected the co-localization of LAT and CD59 in lipid rafts by transfecting Jurkat cells with lentivirus vectors carrying the LAT-enhanced green fluorescent protein fusion protein. In addition, LAT and CD59 were shown to have a synergistic effect on the proliferation of Jurkat cells. The results also indicated that CD59 may transfer the palmitate group from phosphatidylinositol to LAT to form LAT palmitate, which then localizes to lipid rafts to regulate T-cell activation. The results of the present study provided novel insights into the role of CD59 in T-cell signal transduction.