gebhart/patrepeval huggingface dataset:
A learning-based jam session system that imitates a player's personality model (2003)

This paper describes a jam session system that enables a human player to interplay with virtual players which can imitate the player personality models of various human players. Previous systems have parameters that allow some alteration in the way virtual players react, but these systems cannot imitate human personalities. Our system can obtain three kinds of player personality models from a MIDI recording of a session in which that player participated - a reaction model, a phrase model, and a groove model. The reaction model is the characteristic way that a player reacts to other players, and it can be statistically learned from the relationship between the MIDI data of music the player listens to and the MIDI data of music improvised by that player. The phrase model is a set of player's characteristic phrases; it can be acquired through musical segmentation of a MIDI session recording by using Voronoi diagrams on a piano-roll. The groove model is a model that generates onset time deviation; it can be acquired by using a hidden Markov model. Experimental results show that the personality models of any player participating in a guitar trio session can be derived from a MIDI recording of that session.
Nerve-sparing procedure in radical prostatectomy: A risk factor for hernia repair following open retropubic, pure laparoscopic and robot-assisted laparoscopic procedures (2011)

These findings suggest that the nerve sparing procedure may increase the risk of hernia repair. Prospective studies are warranted to investigate the possible adverse effects of the nerve sparing technique.
A two-stage cyclone using microcentrifuge tubes for personal bioaerosol sampling (2006)

Personal aerosol samplers are widely used to monitor human exposure to airborne materials. For bioaerosols, interest is growing in analyzing samples using molecular and immunological techniques. This paper presents a personal sampler that uses a two-stage cyclone to collect bioaerosols into disposable 1.5 ml Eppendorf-type microcentrifuge tubes. Samples can be processed in the tubes for polymerase chain reaction (PCR) or immunoassays, and the use of multiple stages fractionates aerosol particles by aerodynamic diameter. The sampler was tested using fluorescent microspheres and aerosolized fungal spores. The sampler had first and second stage cut-off diameters of 2.6 microm and 1.6 microm at 2 l min(-1)(geometric standard deviation, GSD = 1.45 and 1.75), and 1.8 microm and 1 microm at 3.5 l min(-1)(GSD = 1.42 and 1.55). The sampler aspiration efficiency was >or=98% at both flow rates for particles with aerodynamic diameters of 3.1 microm or less. For 6.2 microm particles, the aspiration efficiency was 89% at 2 l min(-1) and 96% at 3.5 l min(-1). At 3.5 l min(-1), the sampler collected 92% of aerosolized Aspergillus versicolor and Penicillium chrysogenum spores inside the two microcentrifuge tubes, with less than 0.4% of the spores collecting on the back-up filter. The design and techniques given here are suitable for personal bioaerosol sampling, and could also be adapted to design larger aerosol samplers for longer-term atmospheric and indoor air quality sampling.
Correlating Risk Findings to Quantify Risk (2012)

Research in quantitative Information Technology (IT) risk analysis has increased in the past decade, but much of that research has focused on creating new approaches that replace existing ones. Since organizations have extensive sunk costs invested in their risk management programs, there exists a need to extend and improve existing approaches. Additionally, many quantitative approaches are difficult to implement without mathematical expertise or specialized tools, focus on quantifying individual vulnerabilities, provide little insight into underlying process gaps affecting IT risk and do not facilitate including environmental factors in risk ratings. Our research focuses on identifying attributes or characteristics of risk that are missing from existing approaches, and quantifying their relevance using statistical analysis techniques. We seek to identify and quantify attributes that further close the gap between enumerating IT risks and understanding the actual risk they present. In this paper we identify the relationship between risk findings as a key attribute, and demonstrate using correlation to quantify the relationship. Correlation analysis enables organizations to uncover process gaps, and situations where default risk ratings may not be sufficient. In this paper, we discuss the benefits of correlating risk findings and demonstrate value and feasibility through an empirical case study.
Abstract TP64: IV tPA Treatment of Minor Stroke Using MRI Targets Rather Than Clinical Severity (2019)

Background: It is unknown whether patients with non-disabling minor acute ischemic stroke (mAIS) at presentation benefit from IV tPA. The CT-based PRISMS trial suggested no benefit, but was inconclusive due to early termination for low enrollment. Conversely, we have observed an increasing trend in IV tPA treatment of mAIS patients screened with MRI. In this study, we sought to determine our IV tPA treatment rate of patients with mAIS and describe the frequency of MRI targets of acute ischemic stroke (AIS) for these patients stratified by clinical severity. Methods: Patients were included in this study if: 1) treated with IV tPA for AIS from 2015-2017, 2) baseline MRI, and 3) NIHSS&lt;6. Baseline MRI was evaluated (2-rater with 3rd tie breaker) for AIS targets on DWI, PWI, GRE, FLAIR, and MRA. Patients were retrospectively categorized as “disabling” vs. “non-disabling” based on NIHSS (“non-disabling” defined as maximum 1 point each for visual fields, facial palsy, sensation, and dysarthria only). Frequency of AIS targets on MRI were compared between the two groups. Results: Of 305 patients treated with IV tPA, 140 (46%) had mAIS (NIHSS&lt;6), 119 of 140 (85%) had baseline MRI, 53 of 119 (45%) were “non-disabling.” There was no difference in presence of these imaging targets between “disabling” vs. “non-disabling” mAIS patients: DWI lesion, 86.4% vs. 88.7%, p=0.705; PWI lesion, 80.3% vs. 79.2%, p=0.685; PWI/DWI mismatch, 62.1% vs. 50.9%, p=0.337; FLAIR HVS, 48.5% vs. 43.4%, p=0.775; MRA LVO, 24.2% vs. 26.4%, p=0.829, MRA LVO location, p=0.91. There was a trend toward greater visualization of GRE thrombus in the “disabling” group: 40.9% vs. 24.5%, p=0.060. “Non-disabling” mAIS patients treated based on MRI target accounted for 17% of all IV tPA-treated patients. Conclusions: In MRI-screened patients with mAIS, there is no difference in frequency of AIS imaging targets in those with “disabling” vs. “non-disabling” deficit. These findings suggest that these MRI targets rather than clinical severity could be used to drive the decision to treat mAIS patients with IV tPA and greatly expand the pool of patients for thrombolytic therapy. The similarities of these imaging targets in mAIS patients with and without disabling deficit can be used to justify an MRI-based treatment trial.
p56lck Signals for Regulating Thymocyte Development Can Be Distinguished by Their Dependency on Rho Function (1998)

The tyrosine kinase p56lck regulates the differentiation and proliferative expansion of pre-T cells. However, nothing is known about other signaling molecules that operate with p56lck to mediate the pleiotropic changes that occur at this stage of thymocyte development. We used a genetic strategy to examine the requirement for the GTPase Rho in p56lck-mediated signals in the thymus. By generating mice double transgenic for a constitutively activated form of p56lck (p56lckF505) and the Rho inhibitor C3 transferase we were able to compare thymocyte development in mice expressing active p56lck on a wild-type or Rho- background. Thymocytes expressing active p56lck show enhanced proliferation of pre-T cells resulting in increased numbers of late pre-T cells, however, this dramatic effect on pre-T cell proliferation is lost when the p56lck transgene is expressed in thymocytes lacking endogenous Rho GTPase function. Expression of active p56lck also generates double positive (DP) thymocytes with low levels of CD2 antigen expression. Again, p56lck cannot prevent expression of CD2 when expressed on a Rho- background. CD4(+)CD8(+) DP cells expressing active p56lck have been shown to lack functional alpha/beta-T cell receptor (TCR) complexes due to p56lck-mediated inhibition of TCR gene Vbeta-Dbeta rearrangement. This inhibition of TCR expression by active p56lck is unimpaired in the absence of Rho function. The signaling pathways that are mediated by p56lck and control thymocyte proliferation, alpha/beta-TCR and CD2 antigen expression can thus be distinguished by their dependency on Rho function.
Theoretical and experimental investigations of Coulomb blockade in coupled quantum dot systems (2008)

Two strongly coupled quantum dots are theoretically and experimentally investigated. In conductance measurements on a GaAs based low-dimensional system additional features to the Coulomb blockade have been detected at low temperatures. These regions of finite conductivity are compared with theoretical investigations of a strongly coupled quantum dot system and good agreement between the theoretical and the experimental results has been found.
Preferential activation of Th2 cells in chronic graft-versus-host reaction (1993)

The injection of DBA/2 parental lymphocytes into adult, immunologically intact (C57BL/6 x DBA/2) F1 hybrid mice results in a chronic graft-vs-host reaction (GVHR) characterized by a deficiency in CD4+ T cell functions and a B cell activation leading to autoantibody production. The discovery that distinct subpopulations of Th cells may regulate the effector immune functions led us to investigate whether the chronic GVHR differentially affects Th subsets. Data are presented indicating that mice undergoing a GVHR spontaneously produced lymphokines of Th2 origin. IL-4 and IL-10 mRNA were detected in the spleens of GVH mice, and IL-4 was shown to be responsible for the increased expression of class II Ag on B cells. Moreover, upon polyclonal activation in vitro, GVH T cells exhibited defective IL-2 and IFN-gamma production but elevated IL-4 production. We conclude that the chronic GVHR is characterized by a selective deficiency in cells secreting IL-2 and IFN-gamma and a hyperactivation of Th2 cells. The simultaneous production of IL-4 and IL-10 might explain the association between B cell hyperactivity and impairment of Th1-like activities in various models that associate autoimmunity and immunosuppression, such as GVHR and HIV infection.
Therapeutic interventions for enhancing collateral development by administration of growth factors: basic principles, early results and potential hazards (2001)

The importance of spontaneously developing collateral vessels to supplement perfusion of tissue rendered ischemic by vascular obstruction was recognized many years ago. However, it was not until potent angiogenesis factors were identified, purified, and produced in sufficient quantities, that the field began its rapid development. In the early 1990s it was first shown that basic fibroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF) proteins could actually stimulate collateral flow. However, additional studies also demonstrated that the duration of exposure of the vessels to angiogenesis factors was critical, and that the administration of proteins, with their relatively brief half-lives, may pose important practical limitations. The demonstration that gene therapy can improve collateral function presents one of the solutions to the conundrum, since gene therapy can be considered a sophisticated form of a sustained delivery system. The results of several clinical trials have been reported. All involve administration of single angiogenesis agents, and most are Phase I trials. The two studies rising to Phase II status demonstrated no treatment effect on the primary end-point. It may therefore be relevant to consider that the molecular mechanisms responsible for angiogenesis are extraordinarily complex, and an optimal angiogenesis intervention may require a 'multiple factor' strategy. It is important to note that no serious side-effects ascribable to an angiogenesis agent were recognized in these trials. However, angiogenesis agents are potent molecules with multiple activities. It is therefore possible that they might occasionally cause side-effects, some serious. Among these, based on their biologic activities, are neovascularization of non-targeted tissues, expansion and induction of instability of atherogenic plaque, and growth of tumors. In summary, there is ample experimental evidence justifying an optimistic outlook relating to our eventually being successful in enhancing collateral flow to ischemic tissue in a clinical setting. However, we are not there yet, and identification of the optimal angiogenesis strategy is still unclear. Additional experimental work, in parallel with large, carefully controlled clinical trials are needed to continue the exciting advances of the last decade, and to achieve the goal of providing patients with alternative potent therapies to improve collateral flow, and thereby to alleviate their symptoms and perhaps to prolong their lives.
Real-time collision detection and response for complex environments (2002)

Presents a method for collision detection that is well suited to complex environments, such as those obtained from medical imaging and for objects that are in permanent contact. The method is based on a point-in-tetrahedral-mesh query. Spatial and temporal coherence are used to achieve interactive speed. In addition to collision detection, the system calculates a force and torque that can be used for collision response. Experimental results show that it performs well compared to the RAPID (Robust and Accurate Polygon Interference Detection) collision detection library, which is a standard in the field.
Fire dynamics inside a large and open‐plan compartment with exposed timber ceiling and columns: CodeRed #01 (2022)

Summary There is an increasing global demand to build from timber as it is a sustainable and attractive material. One of the key challenges associated with timber buildings is their performance in a fire, in particular, for medium‐ and high‐rise buildings and when timber is exposed. Research on this topic to date has been performed in compartments smaller than 84 m 2 which does not capture the fire dynamics of large compartments. This paper presents the first in a series of experiments carried out inside a large, purpose‐built, open‐plan compartment with a floor area of 352 m 2 . The large‐scale compartment had a fully exposed, unloaded, cross‐laminated timber (CLT) ceiling and glued laminated timber (glulam) columns, made with adhesives that have been tested to not exhibit char fall‐off in fire. At 352 m 2 floor area, this is currently the largest compartment fire experiment carried out globally. The compartment characteristics and the arrangement of the wood crib mimicked the previous series of experiments in Poland in a non‐combustible compartment by Rackauskaite et al. (2021). The experiment was instrumented with thermocouples measuring the gas temperature in the compartment, and above two of the openings, as well as the temperature within the timber members. Plate thermometers were also included to measure the heat flux to the ceiling and of the external flaming. Additionally, fixed and drone‐mounted cameras captured the fire. A protected steel column was added to calculate the equivalent fire exposure when compared to a standard fire resistance furnace test. The experiment was allowed to burn out without fire‐fighting intervention. Continuous measurements were taken for 48 h. The wood crib was ignited at one end of the compartment. Flames rapidly spread across the timber ceiling to the other end of the compartment with the rest of the wood crib being involved in the fire at 5 min 36 s from ignition. The total duration of the fire was 22 min 30 s, at which time visible flaming ceased. Significant external flaming was observed through the openings in the order of 3 m in height but varied with position as the fire travelled across the compartment. Analysis of the experimental results and camera footage showed that the presence of the timber structure approximately doubled the heat release rate (HRR) compared to the value expected from the wood crib alone. Smouldering combustion of the timber members continued for hours after the cessation of flaming, burning in several hotspots, resulting in holes through the CLT slab. This paper improves the understanding fire dynamics for open‐plan, exposed timber compartments and has shown that issues such as external flaming, smouldering and the increase in HRR need to be considered when deriving practical design solutions.
Mutagenecity evaluation of insecticidal 2-carbomethoxy-4-chlorodiethyl phosphate in short-term bioassays (1998)

For evaluating the mutagenic potential of 2-carbomethoxy-4-chlorodiethyl phosphate, three different short-term mutagenicity tests were used; Salmonella typhimurium preincubation assay with and without rat liver microsomal activation, chromosome aberration test in cultured chinese hamster lung fibroblast cell and in vivo micronucleus test in male mice bone marrow. In Salmonella typhimurium reverse mutation assay using TA98, TA100, TAl535 and TAl537, 2-carbomethoxy-4-chlorodiethyl phosphate did not show any mutagenic response in the presence and absence of S9 mix. It did not induce any significant structural chromosome aberrations in the absence of metabolic activation. In micronucleus test using ICR mice, the frequency of micronucleated polychromatic erythrocytes (MNPCE) increased in bone marrow cells treated with positive control, mitomycin-C, but 2-carbomethoxy-4-chlorodiethyl phosphate did not increase micronucleated polychromatic erythrocytes. These results indicate that 2-carbomethoxy-4-chlorodiethyl phosphate does not show any positive responses in short-term genotoxicity assays.
Clover Constituents, Isolation of Daphnoretin from Ladino Clover (1964)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTClover Constituents, Isolation of Daphnoretin from Ladino CloverA. L. Livingston, E. M. Bickoff, and Leonard JurdCite this: J. Agric. Food Chem. 1964, 12, 6, 535–536Publication Date (Print):November 1, 1964Publication History Published online1 May 2002Published inissue 1 November 1964https://pubs.acs.org/doi/10.1021/jf60136a013https://doi.org/10.1021/jf60136a013research-articleACS PublicationsRequest reuse permissionsArticle Views35Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Direct Contact with Endoderm-Like Cells Efficiently Induces Cardiac Progenitors from Mouse and Human Pluripotent Stem Cells (2012)

Our co-aggregation method provides an efficient, simple and cost-effective way to induce CPCs from mouse and human pluripotent cells.
Semi-global Stereo Matching with Surface Orientation Priors (2017)

Semi-Global Matching (SGM) is a widely-used efficient stereo matching technique. It works well for textured scenes, but fails on untextured slanted surfaces due to its fronto-parallel smoothness assumption. To remedy this problem, we propose a simple extension, termed SGM-P, to utilize precomputed surface orientation priors. Such priors favor different surface slants in different 2D image regions or 3D scene regions and can be derived in various ways. In this paper we evaluate plane orientation priors derived from stereo matching at a coarser resolution and show that such priors can yield significant performance gains for difficult weakly-textured scenes. We also explore surface normal priors derived from Manhattan-world assumptions, and we analyze the potential performance gains using oracle priors derived from ground-truth data. SGM-P only adds a minor computational overhead to SGM and is an attractive alternative to more complex methods employing higher-order smoothness terms.
Real-Space Observation of Surface States on Si(111) 7×7 with the Tunneling Microscope (1985)

We have observed surface states indigenous to the Si(111) 7\ifmmode\times\else\texttimes\fi{}7 superlattice with the tunneling microscope. The data show the states' energies and strengths to be strongly dependent on position in the unit mesh. Implications of this for structural models of the 7\ifmmode\times\else\texttimes\fi{}7 superlattice are discussed.
Catheter hole making. (2008)

The science and technology of making good quality holes in tubing is an important issue for the success of the application. The process options and their benefits and limitations are examined.
Space weathering on Eros: Constraints from albedo and spectral measurements of Psyche crater (2001)

Abstract— We present combined multi‐spectral imager (MSI) (0.95 μm) and near‐infrared spectrometer (NIS) (0.8–2.4 μm) observations of Psyche crater on S‐type asteroid 433 Eros obtained by the Near‐Earth Asteroid Rendezvous (NEAR)—Shoemaker spacecraft. At 5.3 km in diameter, Psyche is one of the largest craters on Eros which exhibit distinctive brightness patterns consistent with downslope motion of dark regolith material overlying a substrate of brighter material. At spatial scales of 620 m/ spectrum, Psyche crater wall materials exhibit albedo contrasts of 32–40% at 0.946 μm. Associated spectral variations occur at a much lower level of 4–8% (±2–4%). We report results of scattering model and lunar analogy investigations into several possible causes for these albedo and spectral trends: grain size differences, olivine, pyroxene, and troilite variations, and optical surface maturation. We find that the albedo contrasts in Psyche crater are not consistent with a cause due solely to variations in grain size, olivine, pyroxene or lunar‐like optical maturation. A grain size change sufficient to explain the observed albedo contrasts would result in strong color variations that are not observed. Olivine and pyroxene variations would produce strong band‐correlated variations that are not observed. A simple lunar‐like optical maturation effect would produce strong reddening that is not observed. The contrasts and associated spectral variation trends are most consistent with a combination of enhanced troilite (a dark spectrally neutral component simulating optical effects of shock) and lunar‐like optical maturation. These results suggest that space weathering processes may affect the spectral properties of Eros materials, causing surface exposures to differ optically from subsurface bedrock. However, there are significant spectral differences between Eros' proposed analog meteorites (ordinary chondrites and/or primitive achondrites), and Eros' freshest exposures of subsurface bright materials. After accounting for all differences in the measurement units of our reflectance comparisons, we have found that the bright materials on Eros have reflectance values at 0.946 μm consistent with meteorites, but spectral continua that are much redder than meteorites from 1.5 to 2.4 μm. Most importantly, we calculate that average Eros surface materials are 30–40% darker than meteorites.