gebhart/patrepeval huggingface dataset:
PSUN330 Patients with Recurrent Hypoglycemia Encounters Across Chicago: Who are they? (2022)

Abstract Hypoglycemia is an acute complication of diabetes management that has been linked to increased morbidity. Although current guidelines have called for treatment changes for avoidance of hypoglycemia, it remains a critical issue. Our goal was to examine the socio-demographic and clinical factors for recurrent hypoglycemic encounters across a large metropolitan area. CAPriCORN is a research network which brings together merged, de-duplicated, and de-identified electronic medical health record data from 6 institutions across Chicago. Patients with a diabetes diagnosis and hypoglycemic encounters (HEs) between 2011-18 were identified using ICD-9 and 10 codes. HEs were identified using a validated algorithm. Analysis was performed to evaluate the patient characteristic differences between patients with 1 vs 2-3 vs ≥4 HEs utilizing chi-square for categorical variables and ANOVA for continuous variables. Of 423,643 patients identified with a diagnosis of diabetes, 17,885 (4%) patients had at least one diagnosis of hypoglycemia, which included 30,157 unique encounters (1 HE: 12,886 pts and encounters; 2-3: 3,640 pts and 8,238 encounters, and ≥4: 1,359 pts and 9,033 encounters). The 1,359 patients with ≥4 HEs (8% of all patients with HEs) accounted for over 30% of all HEs. Older adults (65 years and older) comprised 57% of all patients and 62% of patients with HEs. Older adults comprised 63% of those with 1 HE, 61% of those with 2-3, and 52% of those with ≥ 4 (p&amp;lt; 0.001). Adults 80 years and older represented &amp;gt; 20% of those in each group. Whites (N=7,203, 40%) and Blacks (N=6,511, 36%) accounted for most with HE, and within each category. Overall, among those with 1, 2-3, and ≥ 4 HEs there were also significant differences by race and ethnicity. Patients with a HE had significant history of complications, including 54% with nephropathy, 24% with neuropathy, and 23% with ophthalmologic complications. However, a history of diabetic ketoacidosis (DKA) was noted in 53% of all patients with a HE, with 49%, 61%, and 66% of patients in 1, 2-3, and ≥4 HEs groups, respectively (p&amp;lt;0.001). Of those with medication information (n=8,938), patients on insulin-only therapy represented 47% of patients with a HE, and 44%, 52%, and 65% of patients who had 1, 2-3, and ≥4 HEs, respectively (p&amp;lt;0.001). Patients on sulfonylureas or meglitinides represented 28% of patients with a HE, and 31%, 25%, and 15% of patients who had 1, 2-3, ≥4 HEs, respectively (p&amp;lt;0.001). Of those with lab information for HbA1c (n=5,259) there was no significant difference between groups. Overall, a small diverse group of patients accounted for a large amount of hypoglycemic encounters. Special attention should be paid to subsets of patients, including older adults, those with a history of DKA, and those on high-risk therapy. Presentation: Sunday, June 12, 2022 12:30 p.m. - 2:30 p.m.
Metal and ceramic matrix composites: Processing, modeling and mechanical behavior; Proceedings of the International Conference, Anaheim, CA, Feb. 19-22, 1990 (1990)

The present conference on metal matrix composite (MMC) and ceramic matrix composite (CMC) processing, fracture and fatigue characteristics, and interfacial and high temperature performance, gives attention to such topics as tape-cast MMC laminates, the fabrication of high temperature fiber-reinforced intermetallic MMCs, diffusion-bonded preform Al-Si MMCs with SiC fiber reinforcement, HIPed SiC particulate-reinforced 6061 Al alloy MMCs, the performance and economics of CMCs, and the shock compression-processing of high performance ceramics. Also discussed are the high temperature properties of Mg9Li laminates, the deformation processing of Al-alumina MMCs, modeling the thermomechanical behavior of glass-matrix composites, interfacial reactions in SiC fiber-reinforced Ti alloy and Ti aluminide composites, carbon fiber-reinforced tin-superconductor composites, and the stereology of some liquid phase-sintered MMCs.
Hepatoprotective Activity of Enicostema Axillare Against CCl4 - Induced Hepatic Injury in Rats. (2007)

Summary To evaluate the hepatoprotective activity of ethanolic extracts of Enicostema Axillare against CCl4 induced hepatic injury in rats. In hepatotoxic rats, liver damage was studied by assessing parameters such as alkaline phosphate (ALP), GOT, GPT, Glucose, Cholesterol and total protein concentration in blood. Hepatic damage is evidenced by rise in the level of alkaline phosphate, GOT, GPT, Glucose, Cholesterol and total protein. Liver shows a tendency to attain near normalcy in animals coadministered with Enicostema Axillare. Values of normal rats for GOT, GPT, alkaline phosphate, serum glucose, serum cholesterol and total protein are 157.89+19.31, 92.24+4.46, 147.75+9.07, 146.44+11.55, 72.14+5.16, 5.65+0.6 in IU/L respectively. Where as in CCl4 treated rats values rose to 247.06+14.26, 184.4+12.11, 171.33+11.39, 180.47+6.92, 73.61+2.59, 3.29+1.38 in IU/L respectively. Silymarin treated rats GPT, AlkPO4, serum-glucose, serum cholesterol and total protein levels values reduced to 179.83+15.91, 141.33+7.37, 190.9+18.15, 61.11+7.30, 6.43+0.70 in IU/L respectively. While in plant extract administered rats GOT, GPT, alkaline phosphate, Glucose, Cholesterol and total protein are 144.84+10.20, 124.34+14.20, 108.58+6.50, 187.11+11.6, 76.52+3.16, 4.45+0.38 in IU/L respectively attained near normal values. There is no significant change in bilurubin of normal rats (0.525 +0.03), CCl4 treated rats (0.49+0.03), Silymarin treated rats (0.53+0.03) and Enicostema Axillare treated rats (0.5+0.05). All these values are expressed as means + S.D. Enicostema Axillare has potent Hepatoprotective activity against CCl4 induced liver damage in rats.
Effect of positioning on ureteric stone retropulsion: ‘gravity works’ (2018)

Alterations in the angle of inclination reduced stone retropulsion during ureteroscopic lithotripsy in an in vitro model to <1 cm. Increasing the incline angle of a patient may effectively preclude retropulsion when performing laser lithotripsy of ureteric stones.
Arc Fault Detection and Discrimination Methods (2007)

Arc waveform characteristics can be evaluated with various methods to recognize the presence of hazardous arc fault conditions. Discussion covers the arc phenomena and how it is generated in a low voltage electrical distribution circuit, as well as the isolation of the presence of hazardous conditions versus conditions that could falsely mimic the presence of an arc fault. Many waveform characteristics and conditions support the detection of hazardous arc faults and foster a more robust design, capable of withstanding unwanted tripping conditions.
NaRuO2 and NaxRuO2×yH2O: New Oxide and Oxyhydrate with Two Dimensional RuO2 Layers. (2004)

Abstract For Abstract see ChemInform Abstract in Full Text.
Sporadic Pheochromocytomas Are Rarely Associated with Germline Mutations in thevhlTumor Suppressor Gene or theretProtooncogene1 (1997)

Pheochromocytoma is a tumor that may occur sporadically or may be a manifestation of a hereditary disease, such as von Hippel-Lindau disease (VHL) and multiple endocrine neoplasia (MEN) type 2. As patients with VHL or MEN type 2 are at risk to develop multiple tumors, they must be distinguished from sporadic cases. We determined the incidence of VHL and MEN type 2 among 62 German patients diagnosed with pheochromocytoma without a history of a hereditary disease. Germline analyses of the vhl gene and exons 10, 11, and 13 of the ret protooncogene were performed by PCR, single strand conformation polymorphism, enzyme digestion, or sequencing. Two patients (3%) showed vhl mutations (95% confidence interval, 1-11%). One patient showed loss of the MspI restriction site at nucleotides 712/713. Another patient had a C/T change at an intronic site that was also detected in 2 of his offspring. No mutations were detected in the ret protooncogene (97.5% confidence interval, 0-6%). In Germany, most sporadic pheochromocytomas are not due to VHL or MEN type 2. Therefore, clinical work-up in patients with pheochromocytoma without signs of hereditary disease is not recommended. However, because the costs of genetic screening are relatively low, and each index case allows optimal care for family members, molecular testing might be cost-effective.
Characterization of cell wall polysaccharides and cellulosic ethanol potential in genotypes of sorghum biomass. (2019)

In this study, the physicochemical characterization of the cell wall polysaccharides of different genotypes of sorghum bicolor, (Sorghum bicolor (L.) Moench) were obtained using the raw biomass and after the chemical pretreatments, with the objective of this culture being a potential source for the production of cellulosic ethanol. Among the evaluated materials two hybrids brown midrib (bmr) sorghum biomass were tested compared to three conventional sorghum biomass hybrids. The lignocellulosic composition of the raw biomass of each genotype, and after acid and alkaline pretreatments was determined for future investigations of improved ethanol yields. The lignocellulosic composition of the biomass of the bmr hybrid 2015B002 and 2015B003 stood out, presenting significantly lower lignin contents (4.63%) than the conventional hybrids (7.15%).The results showed that the acid treatment followed by the alkaline treatment showed the best performance after the enzymatic hydrolysis, supported by the Scanning Electron Microscopy (SEM), Fourier Transform Infrared Analysis (FTIR), Thermal analysis (TG) and crystallinity index analyzes that demonstrated the desired structural modification. Cellulosic ethanol production for the evaluated hybrids ranged from 6,612 to 11,838 liters per hectare per cycle of 180 days.
Can Otolaryngology Compete with Larger Fields Regarding Impact Factor? (2011)

Impact factor (IF) consists of reporting the number of references an average article in a given journal receives over a 2-year period. Despite several valid criticisms, IF has become an important component of academic advancement. The authors sought to investigate the possible relationship between size of specialty field and IF. The top 10 journals of 13 specialty fields were selected based on IF as reported by Journal Citations Reports on the Web of Science. Specialty field population was obtained from the American Board of Medical Specialties. A highly positive correlation (r = 0.9) was noted with smaller fields (eg, otolaryngology) having lower IFs. To overcome this population bias, a percentile-based impact factor (PIF) may be used where the top journal within a field is given 100%, the worst 0%, and all other journals' IFs are proportionately scaled in between the 2 extremes. PIF acts to "level the playing field," allowing between-specialty field comparisons.
An x-ray photoelectron spectroscopy investigation of O impurity chemistry in CdS thin films grown by chemical bath deposition (1997)

We used x-ray photoelectron spectroscopy to investigate the chemistry of O impurity atoms in CdS thin films grown for photovoltaic purposes by chemical-bath deposition (CBD). We compared the Cd 3d photoline, O 1s photoline, Cd MNN Auger line, and O KLL Auger line taken from a CBD CdS thin film, CdS single-crystal reference, Cd metal reference, CdO reference, and Cd(OH)2 reference. This comparison showed that the O present in thin-film CBD CdS is a manifestation of H2O incorporated into the film during the CBD growth. Ar+ ion sputtering, a technique frequently used in thin-film analyses, preferentially removed S from the CBD CdS thin film and created CdS1−xOx (x∼0.04) in the surface region from the incorporated O impurity.
Molecular Cytogenetic Analysis of Polyploidization in the Anther Tapetum of Diploid and Autotetraploid Arabidopsis thaliana Plants (2001)

Abstract Like those of most angiosperms, vegetative tissues of Arabidopsis thaliana undergo high levels of endopolyploidization. One such tissue is the anther tapetum which plays a role in male sporo- and gametogenesis. The degree of polyploidization of the tapetum varies from species to species. Although the role of this process is not yet fully understood, it may be linked to functioning of the tapetum, increasing the copy number of genes needed for the synthesis of specific factors required by developing pollen mother cells (PMCs) and pollen grains. The present study focused on polyploidization during the development of the tapetum of Arabidopsis thaliana . The aim was to outline the mode of tapetum polyploidization in this model plant species and to establish an efficient method for analysing ploidy levels in differentiated cells. The course and degree of tapetum polyploidization in Arabidopsis was analysed in interphase nuclei using fluorescence in situ hybridization (FISH) with repetitive DNA (45S rDNA). The stages of development of the tapetum were analysed alongside meiosis in PMCs. The majority of tapetal cells undergo two, maximally three, rounds of divisions. Tapetal nuclei have usually divided by metaphase I of meiosis of PMCs. The pattern of tapetum polyploidization was similar in diploid and autotetraploid plants and is thus not affected by increasing amounts of maternal plant DNA. The tapetum of autotetraploid plants exhibits a higher frequency of additional division than seen in diploid plants.
Formation de coke à partir de propène sur silicalite (2003)

Sur silicalite et zéolithe MFI acide, l'adsorption du propène a été suivie en microbalance sur une gamme de température variant de 25 à 450 °C et pour une pression d'alcène de 97 kPa. L'analyse de la phase irréversiblement adsorbée (coke) montre que, malgré la faible acidité de la silicalite, dès 25 °C le propène subit des réactions d'oligomérisation. La quantité maximale de coke est obtenue entre 100 et 150 °C. Pour ces températures, des oligomères avec un nombre de carbone non multiple de trois sont présents dans les pores de la zéolithe, des réactions d'oligomérisation et de craquage sont responsables de la formation de ces composés. Dans ces conditions, on peut estimer qu'environ 10 % de coke entraîne le complet blockage des pores de la silicalite. À plus haute température, des composés aromatiques et polyaromatiques sont formés par réactions successives (oligomérisation, craquage, cyclisation, transfert d'hydrogène). La présence des composés polyaromatiques est responsable de la forte désactivation de l'adsorbant par un rapide bloquage de pores. Sur zéolithe acide (Si/Al = 40), les réactions de formation de coke sont plus rapides mais les molécules formées sont similaires à celles identifiées dans les pores de la silicalite.
Mathematical and Physical Foundations of Matching Acupuncture Design in Matrix Acupuncture (2013)

Scientific nature of matrix acupuncture was illustrated from mathematical and physical foundation in order to provide theoretical basis for clinical application of matrix acupuncture.
Aplicación de los métodos de contorno en la flexión de placas (1982)

Los métodos semianalíticos poseen gran idoneidad para abordar problemas estructurales reales, obteniendo los niveles de precisión necesarios con esfuerzos de ordenador menores que los métodos exclusivamente numéricos.
Cover Picture: Plasma Process. Polym. 3/2021 (2021)

Cover Picture: The study demonstrates how a multicomponent target approach can be used inside a gas aggregation cluster source to produce alloy nanoparticles with tunable composition. A considerable impact of redeposition on the composition of alloy nanoparticles was observed. It turned out that the optical emission of sputtered atoms can be used to overcome the issue of redeposition and to enhance the composition control of the synthesis process in operando. Further details can be found in the article by Jonas Drewes, Alexander Vahl, Niko Carstens, Thomas Strunskus, Oleksandr Polonskyi, and Franz Faupel (e2000208).
Lysin CF-301 Demonstrates In Vitro Synergy with Conventional Antibiotics against Staphylococcus aureus (2017)

Abstract Background CF-301 is a novel, recombinantly-produced bacteriophage-derived lysin (cell wall hydrolase) and is the first agent of this class to enter clinical development in the US for the treatment of bacteremia including endocarditis due to S.aureus. This study evaluated the in vitro activity of CF-301 combined with each of 7 antistaphylococcal antibiotics including those considered to be current standard of care treatments for S.aureus bacteremia (daptomycin, vancomycin, oxacillin, nafcillin, and cefazolin) as well as linezolid and telavancin. Methods MICs for CF-301 were determined using a new AST medium for broth microdilution recently endorsed by the CLSI for use with CF-301. The testing medium consisted of cation-adjusted MHB supplemented with 25% horse serum and 0.5 mM DTT. Synergy was determined by checkerboard microdilution using the fractional inhibitory concentration index (FICI) for each combination in triplicate. For each antibiotic tested, an FIC mean was derived from each set of checkerboards by averaging 3 consecutive FIC values along the growth/no growth interface for each plate. Thus, 9 values were, used to generate the final mean. Synergy was defined as an FICI of ≤0.5; indifference was &amp;gt;0.5 to &amp;lt;2; and antagonism was ≥2. Each combination was examined against 10 MSSA and 10 MRSA strains. Results CF-301 synergized with daptomycin and vancomycin against each MSSA and MRSA strain, with FICI values between 0.254 and 0.5. Synergy was similarly observed against all 20 strains tested with oxacillin and nafcillin (FICI = 0.25–0.5); for the third β-lactam, cefazolin, synergy was observed with 17 strains (FICI = 0.75, for the remaining 3 strains). CF-301 synergized with televancin against 70% of the strains (FICI = 0.375–0.5), and was indifferent with the remainder (FICI = 0.625–1). CF-301 synergized with linezolid against 55% of the strains (FICI = 0.375–0.5), and was indifferent with the remainder (FICI = 0.625–0.75). Conclusion The broadly synergistic activity of CF-301 with conventional antistaphylococcal antibiotics against MSSA and MRSA suggests that CF-301 may afford therapeutic benefit by potentiating the activity antibiotics to treat serious infections for which there is an unmet medical need to improve outcomes. Disclosures K. Sauve, ContraFect Corp: Employee, Salary; A. Jandourek, ContraFect Corp: Employee, Salary; C. Cassino, ContraFect Corp: Employee, Salary; R. Schuch, ContraFect Corp: Employee, Salary
A Convenient Oxidative Demasking of 1,3‐Dithiolanes and Dithianes to Carbonyl Compounds with TBHP. (2002)

Abstract For Abstract see ChemInform Abstract in Full Text.
Tumor necrosis factor and external beam radiation (1990)

Division of Hematology and Oncology, Department of Medicine, C2–5, Virginia Muson Medical Center, 1100 Ninth Avenue, Seattle, WA 98111 and the Division of Oncology, Department of Medicine, UCLA School of Medicine, Center for the Health Sciences, 10833 Le Conte Avenue, Los Angeles, CA 90024–1678, USA.
Function of Bean Roots and Stems in Sodium Retention (1964)

Sodium is excluded from the tops of many plants (1-4, 7, 8), and hence accumulation of this ion in the leaves of such plants which apparently are rather sen- sitive to it (2) is avoided. The barrier to sodium transport is effective at moderate external sodium concentrations. At high external concentrations (2, 7, 8), and as a result of prolonged growth in a saline medium (1), sodium contents are found to increase in the stems and sometimes also in the leaves of so-called Na nonaccumulator plants. Gauch and Wadleigh (4) assumed that sodium movement might be restricted by the membranes of certain extrastelar tissue, excluding it from the vascular system. Huffaker and Wallace (8) suggested that the term Na nonaccumulator plant should be considered as a quantitative rather than a qualitative expression. Bernstein et al. (1) found comparable levels of sodium accumulation in the roots, wood, and bark of young apricot trees grown for one year in saline plots; only the leaves and twigs of these plants exhibited restricted sodium accumulation. The authors supposed that sodium had entered the vascu- lar tissue of the trees and that its translocation into the leaves via the transpiration stream had been restricted by retention in the living wood parenchyma cells. During the third year of these experiments sodium levels increased also in the leaves of various stone-fruit trees. Bernstein et al. (1) consider this increase to be due to the development of heart wood during the third year of growth, release of sodium by the senescent parenchyma and its subse- quent translocation into the leaves via the transpira- tion stream.
Synthesis and Biological Activities of Arylspiroborates Derived from 2,3‐Dihydroxynaphthalene (2013)

ABSTRACT A family of arylspiroborate compounds has been prepared from 2,3‐dihydroxynaphthalene and characterized fully using multinuclear NMR spectroscopy and elemental analyses. Single crystal X‐ray diffraction studies were carried out on the tetramethylammonium ( 4 ) and calcium ( 6 ) derivatives. Compound 6 represents the first structurally characterized example of a calcium arylspiroborate salt. All compounds showed modest antifungal and antimycobacterial activities. These results have revealed a new class of compounds that should be further developed to design more potent and selective antitubercular agents. © 2013 Wiley Periodicals, Inc. Heteroatom Chem 24:116–123, 2013; View this article online at wileyonlinelibrary.com . DOI 10.1002/hc.21072
Carbon Nanofibers as Advanced Pd Catalyst Supports for the Air Electrode of Alkaline Metal–Air Batteries (2015)

Carbon nanofibers are investigated as a support for Pd catalysts. The electrochemical behavior of these catalysts for both the oxygen reduction and oxygen evolution reactions is investigated in a half-cell configuration in alkaline solution (6 M KOH) at room temperature. The catalysts are compared with an internal benchmark consisting of Pd supported on Vulcan. Stress tests are also performed to assess the stability of the catalysts under the highly corrosive conditions occurring at the positive electrode, especially during oxygen evolution (high potential). Pd catalysts supported on carbon nanofibers show promising stability characteristics for applications as bifunctional oxygen catalysts in metal-air batteries.
‘Megapclicks’: acoustic click trains and buzzes produced during night-time foraging of humpback whales ( Megaptera novaeangliae ) (2007)

Humpback whales (Megaptera novaeangliae) exhibit a variety of foraging behaviours, but neither they nor any baleen whale are known to produce broadband clicks in association with feeding, as do many odontocetes. We recorded underwater behaviour of humpback whales in a northwest Atlantic feeding area using suction-cup attached, multi-sensor, acoustic tags (DTAGs). Here we describe the first recordings of click production associated with underwater lunges from baleen whales. Recordings of over 34000 'megapclicks' from two whales indicated relatively low received levels at the tag (between 143 and 154dB re 1 microPa pp), most energy below 2kHz, and interclick intervals often decreasing towards the end of click trains to form a buzz. All clicks were recorded during night-time hours. Sharp body rolls also occurred at the end of click bouts containing buzzes, suggesting feeding events. This acoustic behaviour seems to form part of a night-time feeding tactic for humpbacks and also expands the known acoustic repertoire of baleen whales in general.