gebhart/patrepeval huggingface dataset:
DESENVOLVIMENTO DE METAIS DUROS WC-Ni-Si PARA APLICAÇÕES DE ENGENHARIA (2010)

The aim of this work is to make a mechanical and micro structural characterization of a cemented carbide with silicon hardened nickel binder WC-10(Ni-4,1 % Si) processed by powder metallurgy techniques. Micro structural examinations of the specimens indicate the presence of a very low porosity as well as a narrow and relatively constant free mean path between the WC particles. Furthermore, despite the presence of silicon and carbon in the composition, it is not observed the presence of small fractions of non-dissolved SiC and/or free graphite in the microstructure. Vickers hardness and bending tests indicate that the cemented carbide with Ni-4,1% Si binder presented bulk hardness similar to the conventional WC-Co cemented carbides and superior bending resistance and fracture toughness.
Transfer in inverse reinforcement learning for multiple strategies (2013)

We consider the problem of incrementally learning different strategies of performing a complex sequential task from multiple demonstrations of an expert or a set of experts. While the task is the same, each expert differs in his/her way of performing it. We assume that this variety across experts' demonstration is due to the fact that each expert/strategy is driven by a different reward function, where reward function is expressed as a linear combination of a set of known features. Consequently, we can learn all the expert strategies by forming a convex set of optimal deterministic policies, from which one can match any unseen expert strategy drawn from this set. Instead of learning from scratch every optimal policy in this set, the learner transfers knowledge from the set of learned policies to bootstrap its search for new optimal policy. We demonstrate our approach on a simulated mini-golf task where the 7 degrees of freedom Barrett WAM robot arm learns to sequentially putt on different holes in accordance with the playing strategies of the expert.
Time hopping UWB: receiver design and performance of a full-duplex system (2005)

One of the most attractive features of time-hopping UWB transmission, largely ignored in the literature so far, is the possibility to operate in full-duplex mode, thanks to its very low duty-cycle. This allows a terminal to transmit and receive within the same time frame and frequency band, yielding a considerable saving of time and band resources at the radio-resource-management layer. In this paper, we propose a methodology to design channel estimation/synchronization and demodulation/decoding algorithms for a receiver operating in full-duplex mode. The leading idea is simply to avoid, at reception, time intervals that correspond to pulse transmission. We also evaluate the performances of such a system through simulations. From our results, the full-duplex system shows its feasibility for quite a wide range of transmission activity rates.
Importance of valence-band anharmonicity and carrier distribution for third- and fifth-harmonic generation in Si:B pumped with intense terahertz pulses (2022)

We observe third-harmonic generation (THG) and fifth-harmonic generation (FHG) of free holes in the valence band of bulk Si:B at cryogenic temperature upon irradiation with intense terahertz pulses from a free-electron laser, polarized along the $\mathrm{\ensuremath{\Gamma}}\text{\ensuremath{-}}X$ direction. The intensities of both signals increase as a function of pulse energy following power laws with respective exponents of 4.2 and 6.2, larger than the exponents of 3 and 5 expected for ${\ensuremath{\chi}}^{(3)}$ and ${\ensuremath{\chi}}^{(5)}$ processes with constant susceptibilities and a fixed number of holes. The larger values are attributed to the increase in the density of mobile holes, which results from impact ionization of boron dopants by thermally activated holes in the electric field of the terahertz pulses as already observed in our studies of THG in Si:B reported in Phys. Rev. B 102, 075205 (2020). We apply Monte Carlo simulations of the nonlinear heavy- and light-hole field response, coupled with a finite-difference time-domain treatment of the pump-pulse propagation in the sample, which reproduce the experimental THG:FHG intensity ratio reasonably well. An analysis of the local response demonstrates that, in our pump regime, the harmonic generation is dominated by the band anharmonicity as opposed to the energy-dependent momentum scattering rates or interband scattering. Comparison with the results of a simple one-dimensional model and scrutiny of the three-dimensional band structure shows that one must account for the extent of the carrier distribution transverse to the $\mathrm{\ensuremath{\Gamma}}\text{\ensuremath{-}}X$ axis as the anharmonicity grows rapidly away from this axis.
Inertial navigation sensor integrated motion analysis for obstacle detection (2002)

The authors describe a maximally passive system for obstacle detection and avoidance designed for military rotorcraft, which benefits from the use of inertial data. The sensor options are briefly discussed, and sensor fusion needs are mentioned. Some critical system requirements and their effect on system implementation are discussed. In addition, high-level system implementation issues are presented.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Dissolution Behavior of Novolak/Dissolution Inhibitor Resist Systems in an Aqueous Base Developer (1989)

In order to understand the basic mechanisms working in the dissolution of novolak/dissolution inhibitor systems model compounds have been studied in terms of their dissolution inhibition capabilities. The influences of the structure of small size molecules on the inhibition effect were examined as well as the effects of the intramolecular composition and of the molecular weight of polymeric dissolution inhibitors. The role of the novolak type in the inhibition mechanism was also investigated. It was found that an amphiphilic character of the inhibitor molecule and an appropriate structure of the novolak matrix polymer are the most important features for systems with high dissolution inhibition capability. The intramolecular composition of polymeric dissolution inhibitors also has a strong effect, whereas the molecular weight of polymeric dissolution inhibitors has less influence.
κ-Opioid Agonists Directly Inhibit Midbrain Dopaminergic Neurons (2003)

Dopaminergic neurons of the ventral tegmental area (VTA) play a critical role in motivation and reinforcement of goal-directed behaviors. Furthermore, excitation of these neurons has been implicated in the addictive process initiated by drugs such as morphine that act at the micro-opioid receptor (MOR). In contrast, kappa-opioid receptor (KOR) activation in the VTA produces behavioral actions opposite to those elicited by MOR activation. The mechanism underlying this functional opposition, however, is poorly understood. VTA neurons have been categorized previously as principal, secondary, or tertiary on the basis of electrophysiological and pharmacological characteristics. In the present study using whole-cell patch-clamp recordings, we demonstrate that a selective KOR agonist (U69593, 1 microm) directly inhibits a subset of principal and tertiary but not secondary neurons in the VTA. This KOR-mediated inhibition occurs via the activation of a G-protein-coupled inwardly rectifying potassium channel and is blocked by the selective KOR antagonist nor-Binaltorphimine (100 nm). Significantly, regardless of cell class, KOR-mediated inhibition was found only in tyrosine hydroxylase-immunoreactive and thus dopaminergic neurons. In addition, we found a subset of principal neurons that exhibited both disinhibition by a selective MOR agonist ([d-Ala2, N-Me-Phe4, Gly-ol5]-enkephalin) (3 microm) and direct inhibition by KOR agonists. These results provide a cellular mechanism for the opposing behavioral effects of KOR and MOR agonists and shed light on how KORs might regulate the motivational effects of both natural rewards and addictive drugs.
Educational institutes: Wireless network standards, security and future (2010)

Wireless networks have made their mark in higher educational institutes worldwide. The authors have conducted a web-based survey to investigate various aspects of wireless networks in higher education institutes around the world. This paper discusses the findings of the survey results in higher education institutes worldwide. Thirty-six higher education institutes participated in this survey. Three of the institutes filled the survey partially and therefore survey results for thirty-three institutes only were considered. There were seventeen questions in the survey covering topics related to wireless networks only in education institutes. This paper presents the survey results pertaining to wireless network standards, security and future of this technology in education institutes. Most of the earlier studies that have been done prior to this, have covered wireless usage in their own country. This research has attempted to survey countries across the world. For a better understanding of the survey results this paper presents a brief review of different wireless technologies in relation to wireless network security and standards available in the market. Subsequently survey results of wireless network standards, security techniques used by the higher education institutes are depicted and analysed.
Early prediction of transient voltage sags caused by rotor swings (2014)

The paper investigates various methods to predict voltage sags at load buses caused by large generator rotor swings and following a transient disturbance. Three different prediction methods are proposed, which all use real-time measurements from PMUs. One of the methods uses a slightly extended version of the E-SIME method. The other two methods use measurements and process them by recursive least square estimation. It is shown that the prediction method employing E-SIME allows the earliest detection of a critical voltage sag with satisfactory accuracy.
A Study on All-Weather Flexible Auto-tracking Control Strategy of High-Efficiency Solar Concentrating Photovoltaic Power Generation System (2010)

Solar power generation is an important means to solve energy shortage and environmental pollution. In order to improve the efficiency of power generation of high-efficiency solar concentrating photovoltaic power generation system at present, it is required to begin with improving the tracking accuracy of solar concentrating photovoltaic power generation system and improving overall light focusing efficiency, put forward a new solar azimuth all-weather adaptive two-dimensional auto-tracking control method suitable for different weather conditions, utilize real-time control strategies and control parameter auto-optimization methods to realize flexible timing tracking and photoelectric tracking control, make the system be able to monitor weather changes in real time, and perform adaptive selection and control on solar azimuth tracking mode according to different weather conditions to improve solar azimuth tracking precision and the power generation efficiency of photovoltaic power system and reduce the energy consumption of tracking system.
Twin-wire blade forming versus roll forming of a linerboard furnish-effects on tensile strength and formation (2003)

Article Twin-wire blade forming versus roll forming of a linerboard furnish-effects on tensile strength and formation was published on August 1, 2003 in the journal Nordic Pulp & Paper Research Journal (volume 18, issue 3).
Mathematical Simulation of the Sorbent-Based Atmosphere Revitalization System for the Crew Exploration Vehicle (2006)

&lt;div class="htmlview paragraph"&gt;A cyclic adsorption process simulator was used to determine preliminary bed size and characteristics for a sorbent-based atmosphere revitalization (SBAR) system being designed by NASA for the Crew Exploration Vehicle. An initial study of a 2-bed 3-step 3-layer, vacuum swing adsorption cycle, utilizing 50% silica gel, 17% 13X zeolite, and 33% 5A zeolite revealed that a 10 L bed could easily meet the CO&lt;sub&gt;2&lt;/sub&gt; and H&lt;sub&gt;2&lt;/sub&gt; O removal criteria for a 3 person crew. A parametric study showed that the cycle time, layering percentage of silica gel, and H&lt;sub&gt;2&lt;/sub&gt; O-silica gel mass transfer coefficient were important parameters in the SBAR design. Increasing the cycle time diminished the CO&lt;sub&gt;2&lt;/sub&gt; and H&lt;sub&gt;2&lt;/sub&gt; O removal performances but resulted in less O&lt;sub&gt;2&lt;/sub&gt; lost to space. The CO&lt;sub&gt;2&lt;/sub&gt; and H&lt;sub&gt;2&lt;/sub&gt; O removal performances increased considerably when a silica gel layer was added to the bed, with the above layering percentages being close to optimum. As more silica gel was added to the bed slightly more O&lt;sub&gt;2&lt;/sub&gt; was lost. Larger values of the H&lt;sub&gt;2&lt;/sub&gt; O-silica gel mass transfer coefficient improved the CO&lt;sub&gt;2&lt;/sub&gt; and H&lt;sub&gt;2&lt;/sub&gt; O removal performances but at the expense of slightly more O&lt;sub&gt;2&lt;/sub&gt; lost.&lt;/div&gt;
Rings of Controversy: An Analysis of the 2016 Rio Olympic Games Logo Controversy (2012)

The significant resorption of the alveolar bone was observed on the 7th days in the compressive area and the deposition of the alveolar bone was observed on the 14th day in the compressive area after orthodontic force loading.
Self-organization of collaboration networks (2004)

We study collaboration networks in terms of evolving, self-organizing bipartite graph models. We propose a model of a growing network, which combines preferential edge attachment with the bipartite structure, generic for collaboration networks. The model depends exclusively on basic properties of the network, such as the total number of collaborators and acts of collaboration, the mean size of collaborations, etc. The simplest model defined within this framework already allows us to describe many of the main topological characteristics (degree distribution, clustering coefficient, etc.) of one-mode projections of several real collaboration networks, without parameter fitting. We explain the observed dependence of the local clustering on degree and the degree-degree correlations in terms of the "aging" of collaborators and their physical impossibility to participate in an unlimited number of collaborations.
3G base station positioning using simulated annealing (2003)

During the planning of an UMTS radio network, there is a natural need for a base station positioning procedure. Good coverage at an acceptable level of network installation and maintaining costs, low interference and uniform interface load are the main requirements. In this paper we present an approach based on simulated annealing.
Mitochondrial localization of the OAS1 p46 isoform associated with a common single nucleotide polymorphism (2014)

The SNP rs10774671 determines differential expression of the OAS1 isoforms. In Daudi and HT1080 cells the p46 isoform is the most abundantly expressed isoform associated with the G allele, whereas in HeLa cells the most abundantly expressed isoform is p42 associated with the A allele. The SNP rs1131454 (former rs3741981) does not interfere with OAS1 enzyme activity. The OAS1 p46 isoform localizes to the mitochondria, therefore a full 2-5A system can now be found in the mitochondria.
Altered Reactivity of Tertiary Mesenteric Arteries following Acute Myocardial Ischemia (2012)

Acute myocardial ischemia produces peripheral vascular dysfunction; the changes in LC phosphorylation and MYPT1 expression result in a decrease in both tone and the sensitivity to NO-mediated SM relaxation of the peripheral vasculature.
Suppression of ongoing experimental myasthenia by oral treatment with an acetylcholine receptor recombinant fragment (1999)

Myasthenia gravis (MG) is an autoimmune disorder in which the nicotinic acetylcholine receptor (AChR) is the major autoantigen. In an attempt to develop an antigen-specific therapy for MG, we administered a nonmyasthenogenic recombinant fragment of AChR orally to rats. This fragment, corresponding to the extracellular domain of the human AChR alpha-subunit (Halpha1-205), protected rats from subsequently induced experimental autoimmune myasthenia gravis (EAMG) and suppressed ongoing EAMG when treatment was initiated during either the acute or chronic phases of disease. Prevention and suppression of EAMG were accompanied by a significant decrease in AChR-specific humoral and cellular responses. The underlying mechanism for the Halpha1-205-induced oral tolerance seems to be active suppression, mediated by a shift from a T-helper 1 (Th1) to a Th2/Th3 response. This shift was assessed by changes in the cytokine profile, a deviation of anti-AChR IgG isotypes from IgG2 to IgG1, and a suppressed AChR-specific delayed-type hypersensitivity response. Our results in experimental myasthenia suggest that oral administration of AChR-specific recombinant fragments may be considered for antigen-specific immunotherapy of myasthenia gravis.
Abstracts (1959)

Journal Article Abstracts Get access Miriam Reiner Miriam Reiner Search for other works by this author on: Oxford Academic Google Scholar Clinical Chemistry, Volume 5, Issue 2, 1 April 1959, Pages 168–170, https://doi.org/10.1093/clinchem/5.2.168 Published: 01 April 1959
Sensitive New Assay System for Serum Wisteria floribunda Agglutinin-Reactive Ceruloplasmin That Distinguishes Ovarian Clear Cell Carcinoma from Endometrioma (2022)

<i>Wisteria floribunda</i> agglutinin (WFA)-reactive ceruloplasmin (CP) is a candidate marker for ovarian clear cell carcinoma (CCC) reported in our previous paper. Herein, a new measurement system was developed to investigate its potential as a serum marker for CCC. Site-specific glycome analysis using liquid chromatography/mass spectrometry showed that WFA-CP from CCC binds to WFA via the GalNAcβ1,4GlcNAc (LDN) structure. We used mutant recombinant WFA (rWFA), which has a high specificity to the LDN structure, instead of native WFA, to increase the specificity of the serum sample measurement. To improve the sensitivity, we used a surface plasmon field-enhanced fluorescence spectroscopy immunoassay system, which is approximately 100 times more sensitive than the conventional sandwich enzyme-linked immunosorbent assay system. With these two improvements, the specificity and sensitivity of the serum rWFA-CP measurement were dramatically improved, clearly distinguishing CCC from endometrioma, from which CCC originates. This rWFA-CP assay can be used clinically for the serodiagnosis of early-stage CCC, which is difficult to detect with existing serum markers.
A CASE OF PHYLLODES TUMOR DIAGNOSED BY ANALYZING CLONALITY (2000)

We encountered an extremely large benign phyllodes tumor of the mammary gland. This time, by using a polymerase chain reaction and by analyzing clonality of a phyllodes tumor, we have gained insight into tissue genesis. A 45-year-old woman was admitted to the hospital becausee of left breast pain and swelling. On admission, she had a 18×16cm carcinoma tumor with redness in the left breast area. It was diagnosed as phyllodes tumor by an aspiration biopsy cytology. An Auchincloss operation was performed. Pathological diagnosis revealed benign phyllodes tumor. This time, by analyzing clonality of phyllodes tumors, we found that stromal cells of phyllodes tumors were monoclonal. According to Noguchi and others, epithelial and stromal cells are polyclonal in fibroadenoma, but phyllodes tumor has polyclonal epithelial cells, and monoclonal stromal cells. Discrimination between fibroadenoma and phyllodes tumor is possible by the clonality analysis. Employing the clonality analysis in cytologic examination in the future, preoperative precise diagnosis becomes possible.
Controlled Striatal DOPA Production From a Gene Delivery System in a Rodent Model of Parkinson's Disease (2015)

Conventional symptomatic treatment for Parkinson's disease (PD) with long-term L-3,4-dihydroxyphenylalanine (DOPA) is complicated with development of drug-induced side effects. In vivo viral vector-mediated gene expression encoding tyrosine hydroxylase (TH) and GTP cyclohydrolase 1 (GCH1) provides a drug delivery strategy of DOPA with distinct advantages over pharmacotherapy. Since the brain alterations made with current gene transfer techniques are irreversible, the therapeutic approaches taken to the clinic should preferably be controllable to match the needs of each individual during the course of their disease. We used a recently described tunable gene expression system based on the use of destabilized dihydrofolate reductase (DD) and generated a N-terminally coupled GCH1 enzyme (DD-GCH1) while the TH enzyme was constitutively expressed, packaged in adeno-associated viral (AAV) vectors. Expression of DD-GCH1 was regulated by the activating ligand trimethoprim (TMP) that crosses the blood-brain barrier. We show that the resulting intervention provides a TMP-dose-dependent regulation of DOPA synthesis that is closely linked to the magnitude of functional effects. Our data constitutes the first proof of principle for controlled reconstitution of dopamine capacity in the brain and suggests that such next-generation gene therapy strategies are now mature for preclinical development toward use in patients with PD.
Motion U-Net: Multi-cue Encoder-Decoder Network for Motion Segmentation (2021)

Detection of moving objects is a critical component of many computer vision tasks. Recently, deep learning architectures have been developed for supervised learning based moving object change detection. Some top performing architectures, like FgSegNet are single frame spatial appearance cue-based detection and tend to overfit to the training videos. We propose a novel compact multi-cue autoencoder deep architecture, Motion U-Net (MU-Net) for robust moving object detection that generalizes much better than FgSegNet and requires nearly 30 times fewer weight parameters. Motion and change cues are estimated using a multi-modal background subtraction module combined with flux tensor motion estimation. MU-Net was trained and evaluated on the CDnet-2014 change detection challenge video sequences and had an overall F-measure of 0.9369. We used the unseen SBI-2015 video dataset to assess generalization capacity where MU-Net had an F-measure of 0.7625 while FgSegNet_v2 was 0.3519, less than half the MU-Net accuracy. The source code of the Motion U-Net is available at https://github.com/CIVA-Lab/Motion-U-Net.
Model predictive control for railway networks (2002)

Model predictive control (MPC) is a very popular controller design method in the process industry. MPC often uses linear discrete-time models. In this paper we extend MPC to a class of discrete-event systems with both hard and soft synchronization constraints. Typical examples of such systems are railway networks, subway networks, and other logistic operations. In general the MPC control design problem for these systems leads to a nonlinear non-convex optimization problem. We also show that the optimal MPC strategy can be computed using an extended linear complementarity problem.
Performance Analysis of Turbo Codes and Distributed Turbo Codes in Buffer-Aided Relay Systems (2019)

In this paper, we investigate the performance of a relay selection scheme in a buffer-aided multi-relay network with coded transmissions. We consider: (1) two different coding schemes, i.e., Turbo codes and distributed Turbo codes (DTC) and (2) quasi-static Rayleigh fading channels, where all the links are independent but asymmetric. For each of the aforementioned schemes, we analyze the performance of the system in terms of the average throughput and average delay. In addition, simple and explicit approximations of the asymptotic throughput for infinite buffer size and the high signal-to-noise ratio (SNR) regime are obtained. Our analysis of the asymptotic throughput provides the maximum achievable diversity gain of the system, and the accuracy of the derived analytical framework is assessed when compared to the Monte-Carlo simulations.