gebhart/patrepeval huggingface dataset:
The Effect of Flocculent, Dispersants, and Binder on Wet–laid Process for Recycled Glass Fiber/PA6 Composite (2018)

The papermaking industry has been using the wet-laid process to suspend paper pulp-derived fibers in water and drain the solution through a forming mesh. This process has recently been adopted to produce non-woven, wet-laid fiber-reinforced polymer matrix composite mats. The mats can be post-molded into different complex shapes using compression molding or related processes. The objective of this study was to produce composite panels from wet-laid mats and observe the effect of chemicals used during the process on the mechanical and thermal characteristics of the resulting composite. Two sets of mats were processed using recycled glass fiber with Polyamide 6 (PA6). Flocculent, dispersant and binder (poly(vinyl alcohol) (PVOH)) were added to one of the mats, and the second mat was processed without these chemicals. The addition of these chemicals enhanced the fiber distribution and reduced processing defects in the mats. This was reflected in the mechanical properties of the final product. It was noticed that the flocculent, dispersant and binder volatilized during the compression molding step. Hence, the additives were found not to affect the thermal properties of the consolidated part.
Neural convolutional decoders in the satellite channel (2002)

The neural convolutional decoders (NCD) have been used as an alternative for decoding convolutional codes. The motivation of the NCD is to reduce the hardware complexity of the conventional convolutional decoders and maintain the performance. Simulations are performed under the satellite channel that has the nonlinear distortion. We restrict our attention to the case of coherent QPSK modulation. In this case, the neural networks can learn the nonlinear distortion of the satellite channel including the filtering effects and the nonlinear effects of the traveling-wave tube (TWT) amplifiers. The result shows that the performance of the NCD with a simple structure is almost equal to that of the soft decision Viterbi decoder for the systematic code with 32-bit paths which need 128-bit memory storage. And, the performance difference between the NCD for the systematic code and the soft decision Viterbi decoder for the nonsystematic code is about 1.0 dB and nearly identical to that caused by the dissimilarity of the error-correcting ability in two codes. It is concluded that the NCD would perform as well as the soft decision Viterbi decoder for the nonsystematic code.
The Institutional Development of Business Schools (2014)

Abstract In recent times, the fastest growing part of the higher education system has been business schools. There has been an established set of university-based business schools in the U.S.A. since the early part of the twentieth century. Growth has come in Europe from the 1960s to the 1990s and in Australasia and Asia over the past 20 years. This growth has inevitably attracted the interest of those both applauding and sceptical of these developments, and an increasing amount of scholarly literature on business schools has appeared. The purpose of this book is to assess the character and quality of selected research themes on the study of business schools and to articulate a forward-looking research agenda for the study of business schools as institutions. This book offers novel empirical findings on change and development in business schools. It looks at the causes and consequences of the ranking and branding wars around business schools, in particular, and higher education systems more generally. The book also offers a critique of some of the intellectual, professional and economic challenges facing business schools in the contemporary world.
Prostatic capsule‐ and seminal‐sparing cystectomy for bladder carcinoma: initial results for selected patients (2004)

These early results suggest that PSC is not equivalent to radical cystoprostatectomy for bladder cancer control, despite marked improvements in the functional results. Moreover, in carefully selected patients this approach appears to dramatically increase an unusually high metastasis rate. Therefore, the indications for PSC should be either clearly well defined or abandoned in these patients.
Content delivery network slicing: QoE and cost awareness (2017)

Content Delivery Networks (CDNs) emerged to manage the great amount of content, as well as the transmissions over long distances. In recent years, this concept proves to be a promising solution for emergent enterprises. In this paper, we present a Content Delivery Network as a Service (CDNaaS) platform which can create virtual machines (VMs) through a network of data centers and provide a customized slice of CDN to users. CDNaaS manages a great number of videos by means of caches, transcoders, and streamers hosted in different VMs. However, an optimal placement of VMs with adequate flavors for the different images is required to obtain an efficient slice of CDN. In this work, we argue the need to find a convenient slice for the CDN owner while respecting his performance requirements and minimizing as much as possible the incurred cost. We first formulate the VMs placement problem as two Linear Integer problem solutions, aiming at minimizing the cost and maximizing the quality of experience of streaming. Then, extensive simulation results are presented to illustrate the effectiveness of the proposed models.
Teaching Information Quality in Information Systems Undergraduate Education (1999)

An international association advancing the multidisciplinary study of informing systems. Founded in 1998, the Informing Science Institute (ISI) is a global community of academics shaping the future of informing science.
Abstract 217: Mutations in iron-sulfur cluster proteins are associated with decreased bladder cancer cell senescence and improved survival outcomes (2021)

Abstract Recent tumor genome analyses have cataloged hundreds of mutated genes, including a large population of rarely mutated genes with ill-defined roles in cancer. Here we find that, when considering the 10 genes of the iron-sulfur (Fe-S) pathway as an integrated whole, somatic mutations occur with a higher than expected frequency in 21.3% of bladder tumors. Mutations in these genes are associated with increased survival and mutational burden. Analysis of tumor gene expression highlights a relationship between these Fe-S mutations and signalling regulating proliferation and quiescence, with mutations promoting proliferative programs and abolishing maintenance of quiescence. In bladder tumor cells, we show that replication of this proliferative program, using an DYRK1A kinase inhibitor, promotes sensitivity to genotoxic agents. Furthermore, disruption of Fe-S genes ERCC2, MMS19, CIOA1, BRIP1 or POLD1 promotes cell proliferation and concomitant sensitivity to genotoxic agents. These results suggest a model in which Fe-S pathway mutations are selected due to their ability to bypass DNA damage checkpoints and drive proliferation, an aspect which simultaneously creates vulnerability to chemotherapy and resultant improvements in survival. Citation Format: Devin Patel, Fan Zheng, Michael Chen, Jason Kreisberg, Erica Silva, Trey Ideker, Kate Licon. Mutations in iron-sulfur cluster proteins are associated with decreased bladder cancer cell senescence and improved survival outcomes [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2021; 2021 Apr 10-15 and May 17-21. Philadelphia (PA): AACR; Cancer Res 2021;81(13_Suppl):Abstract nr 217.
Abstract 4873: Epicopy: Measuring DNA copy number variation using high-density methylation microarrays (2015)

Abstract Background: Cancers exploit changes in both genomic copy number and DNA methylation to promote growth and escape tumor-suppressor pathways. Under the 2-hit hypothesis, a single gene is likely to be altered by multiple mechanisms at the same time and integrated analysis can sharpen the focus on the most likely drivers. Requiring larger amounts of input material and imposing additional costs may limit multiplatform analysis, especially in studies using archival tissues with long clinical follow-up information where the nucleic acids are degraded and yields are generally lower than are obtained from fresh tissues. Taking advantage of similarities between methylation arrays and SNP arrays, we developed Epicopy, a robust computational method to identify DNA copy number variation (CNV) using high-density Illumina Human Methylation 450K methylation microarrays, thereby delivering two complementary genetic and epigenetic profiles from a single chip. Methods: Epicopy was developed using data from thyroid carcinoma samples arrayed by The Cancer Genome Atlas (TCGA) and subsequently validated on breast and lung small cell carcinoma TCGA datasets. Using Epicopy, we identified circumstances where CNV information can be reliably measured by methylation microarrays. Results: Using TCGA SNP microarrays as the gold standard to assess the performance of methylation derived CNV data from the thyroid, breast, and lung small cell carcinoma datasets, we showed that Epicopy is able to detect CNVs identified by SNP arrays at a sensitivity of 0.69 and specificity of 0.90. Frequently occurring CNVs identified using Genomic Identification of Significant Targets in Cancer (GISTIC), were identified with even higher accuracy. Conclusion: Epicopy provides a robust method to obtain both copy number and methylation information from a single methylation microarray experiment and will add value to methylation microarrays at no additional cost to the user. Tools to highlight regions of high sensitivity and specificity will also be provided to help users decide on the feasibility of using Epicopy to identify CNVs in regions of interest. Epicopy is implemented in the R statistical language and will be made available as a freestanding package as part of the Bioconductor bioinformatics software project. Citation Format: Soonweng Cho, Hyun-seok Kim, Leslie M. Cope, Christopher B. Umbricht. Epicopy: Measuring DNA copy number variation using high-density methylation microarrays. [abstract]. In: Proceedings of the 106th Annual Meeting of the American Association for Cancer Research; 2015 Apr 18-22; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Res 2015;75(15 Suppl):Abstract nr 4873. doi:10.1158/1538-7445.AM2015-4873
The control strategy of bidirectional Z-source inverter for vehicle system (2012)

The expansion of automotive electronic system and the disadvantage of the traditional voltage source inverter should not be ignored. To complete boost-inverter in single stage and remove the impact of harmonics which is caused by the dead time, this paper presents a bidirectional Z-source inverter for the automotive with 42V DC-BUS. In the paper, the schematic of Z-source was introduced, and the parameters of Z-source network were calculated. The third-harmonic injection method was used for ZSI, and the power transfer was illustrated briefly. The results from simulation and the real platform experiment verify the feasibility and advantages of the proposed topology and control strategy.
Solid-Rotor Material Selection for Squirrel-Cage High-Speed Solid-Rotor Induction Machine (2019)

Squirrel-cage solid-rotor core material selection is investigated using a 1 MW 12000 r/min motor as a case study. Different rotor core materials are analysed: S355, X20Cr13, MoCN315M, Imacro M and AISI430. The mechanical strength of the rotor should naturally be strong enough to withstand the high mechanical stresses caused by the high rotational velocity and the rotor should have high saturation flux density for torque production generation. Finite element models are built in Altair Flux 2D environment. A detailed analysis on the influence of material resistivity on torque production and power factor is carried out. Finally, the motor losses are calculated with sinusoidal supply to see the effect of the rotor core material on the motor efficiency.
On-line Japanese character recognition experiments by an off-line method based on normalization-cooperated feature extraction (2002)

It is shown that an offline character recognition method is effective for use in an online Japanese character recognition. Major conventional online recognition methods have restricted the number and the order of strokes. The offline method removes these restrictions, based on pattern matching of orientation feature patterns. It has been improved with developments in nonlinear shape normalization, nonlinear pattern matching, and the normalization-cooperated feature extraction method. It was used to examine 52,944 online Kanji characters in 1,064 categories. The recognition rate achieved 95.1%, and the cumulation recognition rate within the best five candidates was 99.3%.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
THE AMINO ACID CONTENT OF HUMAN CEREBROSPINAL FLUID IN NORMAL INDIVIDUALS AND IN MENTAL DEFECTIVES* (1961)

This investigation of the concentrations of hydrolysis of glutamine to ammonia, and subse- amino acids in human cerebrospinal fluid (`CSF) quent colorimetric determination of ammonia was stimulated by curiosity as to the mechanism (7-9). The most recent studies by XInauff, Zick- of mental defect in various genetically determined graf and Mialkowsky (10, 11) have used com- diseases. Studies of serum amino acids 'and of bined -high voltage paper electrophoresis and the pattern of their urinary excretion have in re-paper chromatography for the qualitative identifica- cent years made significant contributions to an tion of amino acids in CSF.-They found 25 nin- understanding of the biochemical etiology of some hydrin-positive substances, of which they were types of mental deficiency. But it seems likely able to identify 21. There has been a lack of that in some conditions abnormalities in the bio-agreement among investigators, in particular con- chemistry of the central nervous system may be cerning the normal occurrence of y-aminobutyric overlooked if studies are confined to those metabo-acid, cystine, proline, and methionine in CSF. lites excreted in the urine or to those circulating Most studies to date have failed to show dif- in the blood. Because the CSF is not merely an ferences between the amino acid pattern of nor- ultrafiltrate formed by way of the choroid plexuses, mal CSF and of that found in neurological dis- but is the product of an exchange between -the ease. Exceptions are the reports of high CSF blood and the central nervous system, examination levels of argininosuccinic acid in argininqsuccinicof this fluid may sometimes yield important clues aciduria (1), of phenylalanine in phenylketonuria to deranged cerebral metabolism. In the recently (12), of glutamine in hepatic coma (7-9), and of discovered disorder argininosuccinicaciduria (1), aspartic acid in hereditary cerebellar ataxia (13). for instance, the concentration of argininosuccinic
ISOQUINOLINE DERIVATIVES FROM THE RITTER-TYPE REACTION OF VINYL CATIONS (1984)

Abstract Both silver-assisted reaction of β-arylvinyl bromides and the photolysis in nitriles gave isoquinoline derivatives, indicating that the Ritter reaction involving a vinyl cation took place.
Real-Time Personalization in Adaptive IDEs (2019)

Integrated Development Environments (IDEs) are used for a varietyof software development tasks. Their complexity makes them chal-lenging to use though, especially for less experienced developers. In this paper, we outline our approach for an user-adaptive IDE that is able to track the interactions, recognize the user's intent and expertise, and provide relevant, personalized recommendations in real-time. To obtain a user model and provide recommendations, interaction data is processed in a two-stage process: first, we derive a bandit based global model of general task patterns from a dataset of labeled interactions. Second, when the user is working with the IDE, we apply a pre-trained classifier in real-time to get task labels from the user's interactions. With those and user feedback we fine-tune a local copy of the global model. As a result, we obtain a personalized user model which provides user-specific recommendations. We finally present various approaches for using these recommendations to adapt the IDE's interface. Modifications range from visual highlighting to task automation, including explanatory feedback.
Exploratory Studies to Investigate a Linked Prebiotic Origin of RNA and Coded Peptides. 2nd Communication (2004)

The potentially prebiotic synthesis of ribo-nucleotides by stepwise pyrimidine nucleobase assembly on arabinose-3-phosphate derivatives has been demonstrated in previous work. Consideration of the provenance of pentose phosphates, by aldolisation or sugar phosphorylation, suggested that 2-phosphate derivatives might be generated more easily than 3-phosphate derivatives. In the 2-phosphate series, nucleobase-assembly chemistry to give ribo-nucleotides/nucleic acid can be envisaged from xylo-configured starting materials. In this paper, the derivation of xylose-2-phosphate derivatives by aldol chemistry and attempts to demonstrate subsequent pyrimidine nucleobase assembly are reported.
Acylation Stimulating Protein: Myth, Magic, or Major Metabolic Player (1999)

Human and murine adipocytes synthesize and secrete the three proteins of the alternate complement pathwaythe third component of complement (C3), factor B, and adipsin. When these three interact, the initial product is C3a, which in vivo is almost immediately converted to C3adesarg. This 76 amino acid peptide was thought to be the bioinactive final byproduct of the pathway, but that is true only in an immunologic sense. Acylation Stimulating Protein (ASP) is C3adesarg, and there are considerable in vitro data establishing that ASP is a major determinant of the rate of triglyceride synthesis in adipocytes and therefore that ASP may be a major determinant of the rate of fatty acid entry and release from these critical cells (for review see Ref. 1).
Laser Programmable Vias For Reconfiguration Of Integrated Circuits (1989)

The post process reconfiguration of 2 metal layers integrated VLSI circuits, achieved by via formation in intermetal oxide, was studied with doubled frequency YAG laser (532 nm). The creation of vias is experimented on test patterns placed within 3 circuits of different technology. Vias thus formed are created by thermal effect with mechanism of fusion and by mechanical explosion in the insulating layers. No damage was verified by electrical measurements and SEM cross section studies. For metallizations containing refractory metals, the via yields reached 100 % for patterns of 2.6 &mu;m x 4.7 &mu;m. The feasibility of this process has been established for recovering area of 3 &mu;m x 3 &mu;m. Via resistance was measured to be a few Ohms without resorting to post process annealing and the minimum breakdown current was found to be 150 mA. A via is creatable in a metallic line without damaging others lines as close as 1.5 &mu;m. Reliability test of vias at 125&deg;C and 5 mA showedno failure after 1000 hours. Consequently, creation of vias by laser has been shown to be achievable in a metal interconnection environment conforming to VLSI minimum design rules of 1.2 &mu;m.
Key Parameters in the Manufacture of SiC-Based Composite Materials by Reactive Melt Infiltration (2019)

The manufacture of SiC-based composites is quite widespread, and currently different methods are employed for to produce them. The most efficient method, taking into account the cost/performance ratio, is reactive melt infiltration. It consists in infiltrating liquid silicon into a porous preform that must contain carbon, so that SiC is produced during infiltration. This chemical reaction is, in fact, the driving force of the process. In the present work, the synthesis of two SiC-based composite materials with very different applications and microstructures has been studied and optimized. In both cases, materials have been obtained with suitable properties for the selected applications. One of the materials studied is SiCp/Si for protection systems such as armor jackets, and the other one is Cf/SiC for use in braking systems. For the optimization, the dwell time and the atmosphere (Ar or primary vacuum) were used as variables. It has been found that in both preforms the optimum conditions are 1 hour dwell time and a vacuum atmosphere at 1450 &amp;deg;C. The effect of these parameters on microstructure and infiltration kinetics are discussed.
Pretreatment AKR1B10 expression predicts the risk of hepatocellular carcinoma development after hepatitis C virus eradication (2016)

Chronic hepatitis C patients expressing high levels of hepatic AKR1B10 had an increased risk of HCC development even after SVR.
Use of the XRCC2 promoter for in vivo cancer diagnosis and therapy (2018)

The homologous recombination (HR) pathway is a promising target for cancer therapy as it is frequently upregulated in tumors. One such strategy is to target tumors with cancer-specific, hyperactive promoters of HR genes including RAD51 and RAD51C. However, the promoter size and the delivery method have limited its potential clinical applications. Here we identified the ~2.1 kb promoter of XRCC2, similar to ~6.5 kb RAD51 promoter, as also hyperactivated in cancer cells. We found that XRCC2 expression is upregulated in nearly all types of cancers, to a degree comparable to RAD51 while much higher than RAD51C. Further study demonstrated that XRCC2 promoter is hyperactivated in cancer cell lines, and diphtheria toxin A (DTA) gene driven by XRCC2 promoter specifically eliminates cancer cells. Moreover, lentiviral vectors containing XRCC2 promoter driving firefly luciferase or DTA were created and applied to subcutaneous HeLa xenograft mice. We demonstrated that the pXRCC2-luciferase lentivirus is an effective tool for in vivo cancer visualization. Most importantly, pXRCC2-DTA lentivirus significantly inhibited the growth of HeLa xenografts in comparison to the control group. In summary, our results strongly indicate that virus-mediated delivery of constructs built upon the XRCC2 promoter holds great potential for tumor diagnosis and therapy.
Comparison of double-pass estimates of the retinal-image quality obtained with green and near-infrared light (1997)

We compared retinal point-spread functions obtained by the double-pass method with two different wave-lengths, green (543 nm) and near-infrared (780 nm), in both cases under the best conditions of focus. The best refractive state at each wavelength was determined with two procedures: subjective refraction and analysis of the recorded double-pass images as a function of focus. Since the refraction results agree quite well, we assume that in both cases, green and near-infrared light, most of the light of the central core in the double-pass images comes from a layer close to that of the photoreceptors. The central spread of the double-pass images was also quite similar for the two wavelengths: a width of approximately 2-3 arcmin at half-intensity relative to the peak. However, larger differences were found in the tails of the images, with the infrared images presenting a larger scattering halo, probably as a result of a more important contribution of retinal and choroidal scattering for that wavelength. By using the central core in the double-pass images and ignoring the tails, we can use the near-infrared data to predict the modulation transfer function measured with the use of green light. These results raise the possibility of using near-infrared illumination the double-pass method to estimate the optical performance of the human eye.