gebhart/patrepeval huggingface dataset:
Broadband Raman amplification in silicon (2008)

Raman gain is a useful nonlinear phenomenon that has made optically pumped silicon lasers and amplifiers a reality. Unfortunately, the bandwidth of Raman gain in silicon is normally rather limited, owing to the narrow Raman linewidths typical of crystalline materials. Here, we report Raman amplification in silicon with a spectrum that is modified by the simultaneous occurrence of self-phase-modulation. This combined nonlinear action produces a broad Raman gain spectrum from a narrowband pump source.
Frequency domain estimation of time varying channels in OFDMA systems: An EM approach (2009)

OFDM modulation combines advantages of high achievable data rates and relatively easy implementation. However, for proper recovery of input, the OFDM receiver needs accurate channel information. Most algorithms proposed in literature perform channel estimation in time domain which increases computational complexity in multi-access situations where the user is only interested in part of the spectrum. In this paper, we propose a frequency domain algorithm for channel estimation in OFDMA systems. The algorithm performs eigenvalue decomposition of channel autocorrelation matrix and approximates channel frequency response seen by each user using the first few dominant eigenvectors. In a time variant environment, we derive a state space model for the evolution of the eigenmodes that help us to track them. This is done using a forward backward Kalman filter. The performance of the algorithm is further improved by employing a data-aided approach (based on expectation maximization).
Use of the disutility ratio in prenatal screening for Down's syndrome (1999)

The value of the triple test depends on the parental evaluation of outcome of pregnancy for a large group of pregnant women. The disutility ratio, as introduced in this study, might be an instrument to elicit these values for individual women in clinical practice.
A Non-parametric Multi-stage Learning Framework for Cognitive Spectrum Access in IoT Networks. (2018)

Given the increasing number of devices that is going to get connected to wireless networks with the advent of Internet of Things, spectrum scarcity will present a major challenge. Application of opportunistic spectrum access mechanisms to IoT networks will become increasingly important to solve this. In this paper, we present a cognitive radio network architecture which uses multi-stage online learning techniques for spectrum assignment to devices, with the aim of improving the throughput and energy efficiency of the IoT devices. In the first stage, we use an AI technique to learn the quality of a user-channel pairing. The next stage utilizes a non-parametric Bayesian learning algorithm to estimate the Primary User OFF time in each channel. The third stage augments the Bayesian learner with implicit exploration to accelerate the learning procedure. The proposed method leads to significant improvement in throughput and energy efficiency of the IoT devices while keeping the interference to the primary users minimal. We provide comprehensive empirical validation of the method with other learning based approaches.
Data Descriptor: Human whole exome genotype data for Alzheimer’s Disease (2022)

Abstract Bigger sample size can help to identify new genetic variants contributing to an increased risk of developing Alzheimer’s disease. However, the heterogeneity of the whole-exome sequencing (WES) data generation methods presents a challenge to a joint analysis. Here we present a bioinformatics strategy for joint calling 20,504 WES samples collected across nine studies and sequenced using ten different capture kits in fourteen sequencing centers in the Alzheimer’s Disease Sequencing Project. gVCFs of samples were joint-called by the Genome Center for Alzheimer’s Disease into a single VCF, containing only positions within the union of capture kits. The VCF was then processed using specific strategies to account for the batch effects arising from the use of different capture kits from different studies. We identified 8.2 million autosomal variants. 96.82% of the variants are high-quality, and are located in 28,579 Ensembl transcripts. 41% of the variants are intronic and 15% are missense variants. 1.8% of the variants are with CADD&gt;30. Our new strategy for processing these diversely generated WES samples has shown to generate high-quality data. The improved ability to combine data sequenced in different batches benefits the whole genomics research community. The WES data are accessible to the scientific community via https://dss.niagads.org/ .
Condensed versus standard schedule of high-dose cytarabine consolidation therapy with pegfilgrastim growth factor support in acute myeloid leukemia (2017)

The aim of this cohort study was to compare a condensed schedule of consolidation therapy with high-dose cytarabine on days 1, 2 and 3 (HDAC-123) with the HDAC schedule given on days 1, 3 and 5 (HDAC-135) as well as to evaluate the prophylactic use of pegfilgrastim after chemotherapy in younger patients with acute myeloid leukemia in first complete remission. One hundred and seventy-six patients were treated with HDAC-135 and 392 patients with HDAC-123 with prophylactic pegfilgrastim at days 10 and 8, respectively, in the AMLSG 07-04 and the German AML Intergroup protocol. Time from start to chemotherapy until hematologic recovery with white blood cells >1.0 G/l and neutrophils >0.5 G/l was in median 4 days shorter in patients receiving HDAC-123 compared with HDAC-135 (P<0.0001, each), and further reduced by 2 days (P<0.0001) by pegfilgrastim. Rates of infections were reduced by HDAC-123 (P<0.0001) and pegfilgrastim (P=0.002). Days in hospital and platelet transfusions were significantly reduced by HDAC-123 compared with HDAC-135. Survival was neither affected by HDAC-123 versus HDAC-135 nor by pegfilgrastim. In conclusion, consolidation therapy with HDAC-123 leads to faster hematologic recovery and less infections, platelet transfusions as well as days in hospital without affecting survival.
Protection Studies in Colostrum-Deprived Piglets of a Bovine Rotavirus Vaccine Candidate Using Human Rotavirus Strains for Challenge (1983)

Studies were performed to evaluate the potential use of the bovine RIT 4237 rotavirus strain as a vaccine candidate against infection with human rotaviruses. Initial experiments revealed that colostrum-deprived piglets were susceptible to infection with several human strains, except for those belonging to subgroup 1. Subsequently, different immunization procedures with RIT 4237 were studied in this animal model. It was found that a two-dose administration, either given intramuscularly (twice) or once intramuscularly and once intragastrically, was necessary to induce a significant serum antibody response. Finally, the protective effect of the latter vaccination schedules against subgroup 2 and 3 rotavirus strains of human origin was evaluated by artificial challenge. In both cases, prior administration of live RIT 4237 significantly decreased fecal shedding of the challenge virus when compared with control animals.
Canine status epilepticus treated with fosphenytoin: A proof of principle study (2015)

This proof of concept study provides the first evidence that FOS is tolerated and effective in canine SE at PHT concentrations clinically relevant for human SE. Furthermore, naturally occurring CSE can be utilized as a translational platform for future studies of novel SE compounds.
High-resolution time-of-flight mass spectrometers: Part I. Effects of field distortions in the vicinity of wire meshes (1989)

Field distortions in the vicinity of wire meshes can change the direction of passing ions. Small deflection angles of ions passing through wire meshes in the reflector can reduce the mass resolution of time-of-flight mass spectrometers. We calculate these effects.
Development of a Screening Tool to Detect theRisk of Inappropriate Prescription Opioid Use inPatients with Chronic Pain (2004)

We have identified six clinical criteria, which were significantly more prevalent in the 'inappropriate opioid use group'. Using these criteria, we have developed a screening tool that appears to predict inappropriate use of prescription opioids in patients with chronic pain.
Far ultraviolet remote sensing of ionospheric emissions by Polar BEAR (1993)

A few thousand far-ultraviolet images of the ionosphere have been obtained since December 1986 by the Atmospheric/Ionospheric Remote Sensor (AIRS) aboard the Polar BEAR satellite. Fast algorithms for applying automated satellite-attitude, geometric, and photometric corrections to these images were developed, and the first results are discussed. A software package that is based on these algorithms was implemented and tested. Since no attitude data is available at night (one of the two gauges is a Sun sensor), an algorithm was devised to extrapolate daytime attitude corrections to nighttime. An additional method is offered to correct satellite roll from the measured or extrapolated one based on the dayglow limbs observed at the edges of the image. Geometric rectifications include transformations to the image from the satellite coordinate system to a reference system, and from the reference system to the geographic coordinate system. Radiometric corrections include image enhancement, background airglow subtraction, and off-nadir normalization of auroral emissions. The latter two are based on theoretical calculations of column emission rates, derived by radiative transfer integrations of volume emission rates along the look direction. Results include mapping of auroral arcs in the corrected geomagnetic system, the one most applicable to auroral studies.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Efficacy of Sildenafil in a Patient With Restless Legs Syndrome/Willis-Ekbom Disease (2015)

Department of Public Health and Clinical Medicine Umeå University Umeå, Sweden [email protected] Department of Exercise Sciences Brigham Young University Provo, UT
Excitation of single-photon embedded eigenstates in coupled cavity–atom systems (2019)

Confining light in open structures is a long-sought goal in nanophotonics and cavity quantum electrodynamics. Embedded eigenstates provide infinite lifetime despite the presence of available leakage channels, but in linear time-invariant systems they cannot be excited from the outside, due to reciprocity. Here, we investigate how atomic nonlinearities may support single-photon embedded eigenstates, which can be populated by a multi-photon excitation followed by internal relaxation. We calculate the system dynamics and show that photon trapping, as well as the reverse release process, can be achieved with arbitrarily high efficiencies. We also discuss the impact of loss, and a path toward the experimental verification of these concepts.
The sphere rheometer. II. Dynamic measurements (1984)

For pt.I see ibid., vol.17, no.12, p.1177-82 (1984). The viscoelastic properties of fluids in the frequency range 0.2-20 Hz have been characterised by means of measurement of the motion of the sphere maintained in levitation and submitted to a sinusoidal force in a horizontal plane.
ChemInform Abstract: NEUROTROPIC AND PSYCHOTROPIC AGENTS. CLVII. FLUORINATED TRICYCLIC NEUROLEPTICS: SYNTHESIS AND PHARMACOLOGY OF 2‐CHLORO‐8‐FLUORO‐4‐(4‐METHYLPIPERAZINO)‐4,5‐DIHYDROTHIENO(2,3‐B)‐1‐BENZOTHIEPIN (1982)

Abstract Die Titelverbindung (VId), deren Synthese aus dem Edukt (I) über die angegebenen Zwischenstufen erfolgt, besitzt als Tranquillisator Langzeitwirkung und weist keine neuroleptischen Eigenschaften auf.
Influence of SiCl4 reactive ion etching on the electrical characteristics of GaAs (1991)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation D. Lootens, P. Clauws, P. Van Daele, P. Demeester; Influence of SiCl4 reactive ion etching on the electrical characteristics of GaAs. AIP Conf. Proc. 5 May 1991; 227 (1): 104–107. https://doi.org/10.1063/1.40654 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
No effect of femoral canal jet-lavage on the stability of cementless stems in primary hip arthroplasty: a randomised RSA study with 6 years follow-up (2019)

Washing the bone bed with jet-lavage prior to insertion of cementless stems does not affect the stability of cementless femoral components. No adverse effects were observed.
Uterine natural killer cells: supervisors of vasculature construction in early decidua basalis (2014)

Mammalian pregnancy involves tremendous de novo maternal vascular construction to adequately support conceptus development. In early mouse decidua basalis (DB), maternal uterine natural killer (uNK) cells oversee this process directing various aspects during the formation of supportive vascular networks. The uNK cells recruited to early implantation site DB secrete numerous factors that act in the construction of early decidual vessels (neoangiogenesis) as well as in the alteration of the structural components of newly developing and existing vessels (pruning and remodeling). Although decidual and placental development sufficient to support live births occur in the absence of normally functioning uNK cells, development and structure of implantation site are optimized through the presence of normally activated uNK cells. Human NK cells are also recruited to early decidua. Gestational complications including recurrent spontaneous abortion, fetal growth restriction, preeclampsia, and preterm labor are linked with the absence of human NK cell activation via paternally inherited conceptus transplantation antigens. This review summarizes the roles that mouse uNK cells normally play in decidual neoangiogenesis and spiral artery remodeling in mouse pregnancy and briefly discusses changes in early developmental angiogenesis due to placental growth factor deficiency.
Characterization of semi-insulating (SI) GaAs as photoconductive switch material for high power, UWB microwave applications (1998)

Summary form only given. A Photoconductive Semiconductor Switch (PCSS) based on SI GaAs material and used as a component of a pulse shaping network, has been studied using a 2-3 D semiconductor device and materials simulation code. Simulations include device characteristics at low and very high bias conditions, determination of hold-off voltage, role of traps in the transport mechanism, and the device response mechanism with changes in such parameters as carrier lifetime, trap captures cross-section, etc. Deviations from known characteristics of "lifetime" material were evident and, as expected, results did not display all known characteristics of "relaxation" materials.
API Design Challenges for Open Router Platforms on Proprietary Hardware. (2008)

Most switch vendors have launched “open ” platform designs for routers and switches, allowing code from customers or third-party vendors to run on their proprietary hardware. An open platform needs a programming interface, to provide switchlets sufficient access to platform features without exposing too much detail. We discuss the design of an abstraction layer and API designed to support portability between vendor platforms, isolation between switchlets and both the platform and other switchlets, high performance, and programming simplicity. The API would also support resource-management abstractions; for example, to allow policy-based allocation of TCAM entries among multiple switchlets. 1
The Aldridge Sling Procedure in the Treatment of Urinary Stress Incontinence (1987)

The long-term results of the Aldridge sling procedure for the treatment of recurrent urinary stress incontinence was assessed in 50 women most of whom had had previous failed vaginal surgery; 78% of patients were cured of all symptoms and a further 20% were symptomatically improved--a 2% failure rate. Only one patient reverted from a cure to improved during the lengthy follow-up. The procedure is not difficult to perform and is a good surgical option in patients with failed vaginal surgery.
Analog Adaptive Filtering Techniques for High-Speed Data Communications (1995)

An area receiving significant attention both from academia and industry is data communications. Great effort is being placed at pushing data transmission rates over copper to near the Shannon limit which requires support electronics such as filters operating in the VHF range. Thus, tuning mechanisms are essential to accommodate fabrication and channel variations. One technology to accommodate these variations is that of analog adaptive filtering and is the main topic of this thesis. Specifically, this thesis is an investigation to determine and demonstrate the capability of analog adaptive filtering in practical high-speed applications. The issues that are addressed are the implementation of the tuning algorithm, simple and effective building blocks and the effects of DC offset. Herein, a curve fitting approach is proposed for the adaptation algorithm and focus is placed on simple algorithms and simple filter building blocks that can accommodate a wide tuning range and high speed. Experimental results of a 100Mb/s transmit pulse-shaping filter verify the proposed adaptive techniques and highlight practical problems. This prototype is the first demonstration of an analog adaptive filter operating in the VHF range. Attaining a
Thermally Stimulated Current Separation of Hole and Acceptor Trap Density in 4H-SiC MOS Devices Using Gamma Ray Irradiation (2010)

Thermally stimulated current (TSC) measurements on epitaxial and implanted 4H-SiC MOS capacitors are presented. The effect of gamma ray irradiation on the TSC spectra of epitaxial 4H-SiC MOSCAP devices is discussed. On non-irradiated samples, two TSC peaks are observed near 55 K and 80 K. Due to the generated oxide charge during irradiation, the 80 K emission split into two constituent peaks. These have been attributed to hole traps and Al acceptors.
Pedestrian speed/flow relationships for underground stations (1991)

In 1989 London Underground Limited (LUL) initiated a major review of congestion problems at Underground Stations. A key element in the methodology developed to carry out the assessments was PEDROUTE, a computer package which provides estimates of pedestrian flows and delays in congested station networks. In common with urban traffic assignment procedures, PEDROUTE requires as input relationships between flow and travel time for each of the facilities comprising the network. This article reports on the results of a study commissioned by LUL to derive such relationships. It begins with a description of the analytical aspects of the model fitting and then describes the data and results achieved for each of six types of facility, comparing the preferred fits with the existing relationships derived from previous work. Language: en
A Novel Genome-Information Content-Based Statistic for Genome-Wide Association Analysis Designed for Next-Generation Sequencing Data (2012)

The genome-wide association studies (GWAS) designed for next-generation sequencing data involve testing association of genomic variants, including common, low frequency, and rare variants. The current strategies for association studies are well developed for identifying association of common variants with the common diseases, but may be ill-suited when large amounts of allelic heterogeneity are present in sequence data. Recently, group tests that analyze their collective frequency differences between cases and controls shift the current variant-by-variant analysis paradigm for GWAS of common variants to the collective test of multiple variants in the association analysis of rare variants. However, group tests ignore differences in genetic effects among SNPs at different genomic locations. As an alternative to group tests, we developed a novel genome-information content-based statistics for testing association of the entire allele frequency spectrum of genomic variation with the diseases. To evaluate the performance of the proposed statistics, we use large-scale simulations based on whole genome low coverage pilot data in the 1000 Genomes Project to calculate the type 1 error rates and power of seven alternative statistics: a genome-information content-based statistic, the generalized T(2), collapsing method, multivariate and collapsing (CMC) method, individual χ(2) test, weighted-sum statistic, and variable threshold statistic. Finally, we apply the seven statistics to published resequencing dataset from ANGPTL3, ANGPTL4, ANGPTL5, and ANGPTL6 genes in the Dallas Heart Study. We report that the genome-information content-based statistic has significantly improved type 1 error rates and higher power than the other six statistics in both simulated and empirical datasets.
PREPARATION OF PENTAKIS(2,2,2-TRIFLUOROETHOXY) ARSORANE AND LITHIUM HEXAKIS(2,2,2-TRIFLUOROETHOXY) ARSENATE (1985)

Abstract Tris(2,2,2-trifluoroethyl) arsenite, 4, has been synthesized from 2,2,2-trifluoroethanol and arsenic trichloride. When 4 was allowed to react with chlorine, pentakis(2,2,2-trifluoroethoxy)arsorane, 5, resulted. This material reacted with lithium 2,2,2-trifluoroethoxide, 6, to yield lithium hexakis(2,2,2-trifluoroethoxy) arsenate, 7. A 75As NMR resonance was observed for this material.
Neovascularization induced growth of implanted C6 glioma multicellular spheroids: magnetic resonance microimaging. (1995)

Magnetic resonance imaging has been used to follow noninvasively tumor neovascularization and tumor growth in a model system of multicellular C6 rat glioma spheroids implanted s.c. in nude mice. By positioning a single spheroid approximately 1 cm from the site of incision both the vascularization of the tumor and the wound healing processes were spatially separated and could be simultaneously followed. The model proposed here provides defined initial conditions of tumor geometry and cell proliferative status and separation of initial tumor growth from neovascularization. Magnetic susceptibility relaxation provided an intrinsic marker for blood containing vessels. The implanted spheroid induced vessel growth within 4 days after implantation that was geometrically oriented toward the spheroid and distinct from wound healing at the site of incision. Volume measurements showed a corresponding 4-day lag in growth followed by Gompertz progression. Sham implantation of agarose beads of similar diameter showed no induction of vessel growth, ruling out a direct effect of wound healing. The new vessels penetrating the tumor were highly permeable to the contrast reagent gadolinium-diethylenetriaminepentaacetic acid. This permeability may be due to the action of vascular endothelial growth factor, a major angiogenic growth factor in this system, and a potent permeability factor.