gebhart/patrepeval huggingface dataset:
Design and implementation of knee-ankle exoskeleton for energy harvesting and walking assistance (2022)

Abstract The increasing requirement of powering portable electronic devices can be potentially met by recycling the biomechanical energy generated during the human joint motion through a knee-ankle exoskeleton. In this paper, a knee-ankle exoskeleton is designed to recycle the negative work from the wearer’s knee extension and ankle dorsiflexion. The exoskeleton can convert the mechanical energy into electrical energy for energy harvesting and assist the knee flexion and ankle plantarflexion to reduce the wearer’s metabolic cost during walking. It is mainly composed of two torsion springs, two one-way transmission mechanisms, a gear train, and a generator. The torsion springs can store the elastic energy when the wearer’s ankle and knee joints do negative work and release it to assist walking when positive work is required. The one-way transmission mechanisms are employed to filter the knee flexion and ankle plantarflexion and to convert the knee extension and ankle dorsiflexion into the one-way rotation of the generator by symmetrically arranging the gear train. Finally, experiments are conducted to evaluate the performance of the developed knee-ankle exoskeleton. The experimental results indicate that the exoskeleton can generate an average electrical power of 0.49 W and a maximum instantaneous electrical power of 1.8 W at a walking speed of 5.5 km h −1 during a gait cycle, and reductions of 3.48% ± 0.33%, 9.50% ± 0.29%, and 4.54% ± 0.47% of the average muscle activities of the semitendinosus, soleus, and gastrocnemius during a gait cycle are observed, respectively.
Flavobacterium columnarechemotaxis to channel catfish mucus (2008)

Flavobacterium columnare is a Gram-negative pathogen of many species of wild and cultured fish. Isolates from diseased channel catfish belong to either genomovar I or II. Genomovar II isolates were found to be more virulent than genomovar I isolates. The objective of the present study was to determine whether differences exist in the chemotactic response of these genomovars to mucus obtained from the skin, gills and intestines of healthy channel catfish using the capillary chemotaxis assay. Mucus from the skin and gill induced a greater chemotactic response by F. columnare than mucus from the intestine. Sixty percent of mucus from the skin of individual catfish yielded a positive chemotactic response from F. columnare. Finally, skin mucus induced a greater chemotactic response in genomovar II F. columnare than in genomovar I F. columnare isolates. The data indicate that mucus from channel catfish results in a chemotactic response by F. columnare. This positive chemotactic response may be an important first step for F. columnare colonization of channel catfish skin or gills. Although the role that chemotaxis plays in the virulence of F. columnare is not fully defined, the chemotactic response of genomovar ll isolates suggests that chemotaxis is associated with virulence.
Interactions of gene expression, alternative splicing, and DNA methylation in determining nodule identity (2020)

Soybean nodulation is a highly controlled process that involves complex gene regulation at both transcriptional and post-transcriptional levels. In the present study, we profiled gene expression changes, alternative splicing events, and DNA methylation patterns during nodule formation, development, and senescence. The transcriptome data uncovered key transcription patterns of nodule development that included 9669 core genes and 7302 stage-specific genes. Alternative splicing analysis uncovered a total of 2323 genes that undergo alternative splicing events in at least one nodule developmental stage, with activation of exon skipping and repression of intron retention being the most common splicing events in nodules compared to roots. Approximately 40% of the differentially spliced genes were also differentially expressed at the same nodule developmental stage, implying a substantial association between gene expression and alternative splicing. Genome-wide-DNA methylation analysis revealed dynamic changes in nodule methylomes that were specific to each nodule stage, occurred in a sequence-specific manner, and impacted the expression of 1864 genes. An attractive hypothesis raised by our data is that increased DNA methylation may contribute to the efficiency of alternative splicing. Together, our results provide intriguing insights into the associations between gene expression, alternative splicing, and DNA methylation that may shape transcriptome complexity and proteome specificity in developing soybean nodules.
Design and Analysis of a New Multitoothed Magnetless Doubly Salient Machine (2013)

In this paper, the high temperature superconductor (HTS) winding and multitoothed structure are newly incorporated into the doubly salient (DS) and flux-switching (FS) machines, leading to create two new magnetless machines, namely the HTS-based multitoothed switched reluctance (HTS-MSR) and HTS-based multitoothed flux-switching (HTS-MFS) machines. Consequently, the design equations of the three machines, namely the MSR, HTS-MSR, and HTS-MFS, are formulated. The corresponding performances are analyzed by using the time-stepping finite element method (TS-FEM). By utilizing both torque-producing zones, the two HTS-based machines can achieve better performances than the MSR one. Moreover, the HTS-MFS can offer higher torque density than the HTS-MSR, but associated with larger torque ripple.
NOVEL REACTION OF 2-METHYLENEBENZOTHIAZOLINES WITH 3-(2, 3-DIPHENYL-2-CYCLOPROPENYLIDENE)PENTANE-2,4-DIONE: FORMATION OF 3a,9-DIHYDROCYCLOPENTA[b] [1,4]BENZOTHIAZINES (1982)

Abstract Reactions of 3-substituted 2-methylenebenzothiazolines, generated in situ from the corresponding 2-methylbenzothiazolium salts and triethylamine, with 3-(2,3-diphenyl-2-cyclopropenylidene)pentane-2,4-dione give 3a,9-dihydrocyclopenta[b][1,4]benzothiazine derivatives.
Evaluation of Diagnostic Applications of Monoclonal Antibodies against Avian Influenza H7 Viruses (2010)

A panel of monoclonal antibodies (MAbs) was generated from mice immunized with binary ethylenimine (BEI)-inactivated H7N1 (A/TK/ON/18-2/00) virus. Using a dot blot assay, six of seven MAbs reacted with viruses of the H7 subtype, but not with any of the other 15 hemagglutinin (HA) subtypes tested. Four of the seven MAbs reacted with 14 different H7 isolates, indicating that the MAbs binding epitopes are conserved among viruses of the H7 subtype. The binding epitopes of all seven MAbs were conformational and reacted with the HA1 fraction of the HA protein in Western blots under nonreducing conditions. Applications of these MAbs in the development of rapid tests for H7 subtype viruses were evaluated. The MAbs demonstrated reactivity with AI virus H7 antigen in immunofluorescence and immunohistochemistry assays. Monoclonal antibody 3 showed a very strong immunostaining in the formalin-fixed and paraffin-embedded tissue from the H7N3 virus-infected chicken. A double-antibody sandwich (DAS) enzyme-linked immunosorbent assay (ELISA) was developed using two of the MAbs. The DAS ELISA specifically detected all H7 strains tested in this study. A competitive ELISA (cELISA) for the detection of H7-specific antibodies was evaluated using one MAb and BEI-inactivated H7N1 virus as the antigen. All infected birds showed positive antibody responses at 7 days postinfection. The sensitivity of this cELISA was comparable with that of an influenza A nucleoprotein-based cELISA. This panel of MAbs is valuable in the development of various immunoassays.
miRNA Expression in a Human Papillary Thyroid Carcinoma Cell Line Varies with Invasiveness (2010)

The purpose of these studies was to explore the expression pattern of miRNAs associated with invasion and metastasis of human papillary thyroid carcinoma (PTC). A transwell invasion chamber was used to select progressively more invasive cancer cell populations from a clonal cell line of human PTC with cervical lymph node metastasis, IHH-4. Three sublines with progressive invasiveness, designated IHH-4M-1, IHH-4M-2 and IHH-4M-3, were obtained through this in vitro selection process. The sublines manifested an increase in colony-forming ability on soft agar and metastatic potency in nude mice. Then metastasis-related miRNAs differentially expressed between them were analyzed utilizing the miRNA microarray technique. We found that 11 metastasis-related miRNAs were differentially expressed between the invasive subpopulations and their control subpopulations; these miRNAs may account for their significant difference in the invasion capabilities and favor lymphatic metastasis of PTC.
Yersinia enterocolitica ClpB Affects Levels of Invasin and Motility (2000)

Expression of the Yersinia enterocolitica inv gene is dependent on growth phase and temperature. inv is maximally expressed at 23 degrees C in late-exponential- to early-stationary-phase cultures. We previously reported the isolation of a Y. enterocolitica mutant (JB1A8v) that shows a decrease in invasin levels yet is hypermotile when grown at 23 degrees C. JB1A8v has a transposon insertion within uvrC. Described here is the isolation and characterization of a clone that suppresses these mutant phenotypes of the uvrC mutant JB1A8v. This suppressing clone encodes ClpB (a Clp ATPase homologue). The Y. enterocolitica ClpB homologue is 30 to 40% identical to the ClpB proteins from various bacteria but is 80% identical to one of the two ClpB homologues of Yersinia pestis. A clpB::TnMax2 insertion mutant (JB69Qv) was constructed and determined to be deficient in invasin production and nonmotile when grown at 23 degrees C. Analysis of inv and fleB (flagellin gene) transcript levels in JB69Qv suggested that ClpB has both transcriptional and posttranscriptional effects. In contrast, a clpB null mutant, BY1v, had no effect on invasin levels or motility. A model accounting for these observations is presented.
ASAIO 2018 Annual Meeting Abstracts (2018)

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DMD-based implementation of patterned optical filter arrays for compressive spectral imaging (2014)

Compressive spectral imaging (CSI) captures multispectral imagery using fewer measurements than those required by traditional Shannon-Nyquist theory-based sensing procedures. CSI systems acquire coded and dispersed random projections of the scene rather than direct measurements of the voxels. To date, the coding procedure in CSI has been realized through the use of block-unblock coded apertures (CAs), commonly implemented as chrome-on-quartz photomasks. These apertures block or permit us to pass the entire spectrum from the scene at given spatial locations, thus modulating the spatial characteristics of the scene. This paper extends the framework of CSI by replacing the traditional block-unblock photomasks by patterned optical filter arrays, referred to as colored coded apertures (CCAs). These, in turn, allow the source to be modulated not only spatially but spectrally as well, entailing more powerful coding strategies. The proposed CCAs are synthesized through linear combinations of low-pass, high-pass, and bandpass filters, paired with binary pattern ensembles realized by a digital micromirror device. The optical forward model of the proposed CSI architecture is presented along with a proof-of-concept implementation, which achieves noticeable improvements in the quality of the reconstruction.
Characterization of boria-alumina mixed oxides prepared by a sol-gel method. Part 1: NMR characterization of the xerogels (2005)

While boria-alumina mixed oxides have been widely used for various catalytic reactions, their structure has never been satisfactory elucidated and is still a matter of debates. The present paper deals with the elucidation of the structure of boria-alumina prepared by a sol-gel method with B / Al atomic ratio varying from 0.013 to 1.643. The powders were prepared by hydrolysis of aluminum tri-sec-butoxide in presence of (NH4)2B4O7.4H2O. Then, the solid-state magic angle spinning NMR spectroscopy was used to characterize the obtained solids in the dried state (xerogels), the calcined state being the object of a next paper. Both 27Al and 11B MAS-NMR spectra were recorded with subsequent simulation of these last ones. This allowed to build a consistent structural model of these xerogels, taking into account the evolutions of calculated parameters such as the quadrupolar interaction, the real chemical shift, the relative quantity of respectively BO3, BO4, tetrahedral, pentahedral and octahedral aluminum species as a function of the B / Al atomic ratio. As a result, it was found that for B / Al < 0.06, presence of boron induces the creation of bulk and surface tetrahedral aluminum species. Then, for B / Al > 0.06, BO3 chains attached to these tetrahedral aluminum species are formed and start to grow through the matrix. Further, for B / Al > 0.15, when the boron loading increases, the BO3 chains progressively emerge outside of the matrix, crossing it over. Furthermore, for B / Al > 0.26, some pentahedral aluminum species are formed supposedly due to the considerable steric strains afforded by some particular aluminum atoms. In brief, the presented model elucidates the structure of the dried alumina-based xerogels and is the key starting point to explain the structure of the oxides obtained after calcination and presented in the following paper.
An absolute air pressure smart sensor family with 2 dimensional calibration (1999)

S.254-257
Least squares congealing for unsupervised alignment of images (2008)

In this paper, we present an approach we refer to as "least squares congealing" which provides a solution to the problem of aligning an ensemble of images in an unsupervised manner. Our approach circumvents many of the limitations existing in the canonical "congealing" algorithm. Specifically, we present an algorithm that:- (i) is able to simultaneously, rather than sequentially, estimate warp parameter updates, (ii) exhibits fast convergence and (iii) requires no pre-defined step size. We present alignment results which show an improvement in performance for the removal of unwanted spatial variation when compared with the related work of Learned-Miller on two datasets, the MNIST hand written digit database and the MultiPIE face database.
Tolerability of beta-blockers in heart failure: reassurance needed, reassurance provided. (2003)

In contrast to widely held perceptions regarding tolerability of beta-blockers in heart failure, it is clear that initiation and uptitration is not as complex as perceived. In particular, there is no increased risk of intolerance and/or worsening of heart failure symptoms with initiation of beta-blocker therapy (at least as demonstrated by carvedilol in COPERNICUS). Furthermore, the perceived delay in beneficial effects on outcomes is perhaps challenged by the COPERNICUS study. Interestingly, all of the above observations appear to hold true in patients with advanced disease. Because of the unique history of beta-blockers in systolic heart failure, physicians have needed particular reassurance regarding the tolerability of these agents. Reassurance regarding tolerability has now been definitively provided.
Overcomplete image coding using iterative projection-based noise shaping (2003)

Overcomplete transforms, like the dual-tree complex wavelet transform, offer more flexible signal representations than critically-sampled transforms. Large numbers of transform coefficients can be discarded without much reconstruction quality loss by forcing compensatory changes in the remaining coefficients. We develop and demonstrate a new and unique system for achieving these transform coding aims of coefficient elimination and compensation. The system is based on iterative projection of signals between the image domain and transform domain.
Dielectric microcavities for THz radiation: identical mode spectrum and coupling in poly-ethylene disks (2008)

We report the fabrication and characterization of identical dielectric whispering gallery microcavites for teraherz (THz) radiation. The THz radiation is coupled via a tapered waveguide into the coupled cavities. Mode splitting is observed.
Epigallocatechin gallate incorporation into lignin enhances the alkaline delignification and enzymatic saccharification of cell walls (2012)

It was found that EGCG readily copolymerized with monolignols to become integrally cross-coupled into cell wall lignins, where it greatly enhanced alkaline delignification and subsequent enzymatic saccharification. Improved delignification may be attributed to internal trapping of quinone-methide intermediates to prevent benzyl ether cross-linking of lignin to structural polysaccharides during lignification, and to the cleavage of ester intra-unit linkages within EGCG during pretreatment. Overall, our results suggest that apoplastic deposition of EGCG for incorporation into lignin would be a promising plant genetic engineering target for improving the delignification and saccharification of biomass crops.
The Scaling of Pressure Fluctuations From Equal-Tee Piping Components for In-Plant Noise Prediction (2003)

An important element of in-plant noise modeling for high-speed gas flow, in addition to the noise generated by control valves, is the noise due to piping system components such as tees which becomes significant at high mass flow rates. An effective tool for the modeling of noise due to piping system components is non-dimensional pressure fluctuation scaling. The current paper outlines procedures for characterization of the internal noise due to an equal tee with unequal outlet flows using non-dimensional pressure fluctuation scaling. Experimental data is presented demonstrating general collapse of the measured data onto a single characteristic curve for several combinations of flow velocity and gas density under steady-state flow conditions. Flow ratios of 1:2, 1:3, 1:4 and 2:3 between each of the two outlet legs from the equal tee are considered, as well as the affect of gas density over a range of 345kPaG to 1380kPaG.
Multifunctional Reaction‐Bonded Alumina Coatings for Porous Continuous Fiber‐Reinforced Oxide Composites (2004)

Highly porous, alumina‐based ceramic matrix composites (CMCs), without additional fiber‐matrix interphase, display excellent high‐temperature stability, damage tolerance, and thermal shock resistance. However, the very high gas permeability and the rough CMC surface associated with the winding pattern may give rise to problems in a variety of applications. The solution for these problems is the application of additional functional coatings based on reaction‐bonded alumina (RBAO). RBAO topcoats for porous alumina‐based CMCs were fabricated by a simple painting and firing process. The RBAO topcoats display excellent adherence and provide smoothing and stabilization of the surface and, hence, protection against erosion and wear. The pore structure of the RBAO coats particularly depends on the RBAO starting materials. The gas permeability of RBAO coated CMCs is reduced by several orders of magnitude with respect to uncoated CMCs if optimized ratios between Al and Al 2 O 3 in the RBAO starting compositions are employed. The RBAO coatings also work as suitable bond‐coats for additional plasma‐sprayed environmental barrier coatings.
Application of the UNIFAC‐FV group contribution method to the prediction of relative compatibility of plasticizers with PVC (1988)

Abstract The applicability of a modified version of UNIFAC group contribution method, UNIFAC‐FV, is explored for use in predicting liquid‐liquid equilibrium behavior of plasticizer/PVC systems. A Fortran program for the UNIFAC‐FV model has been written to calculate the activities and changes in the Gibbs free energy for multicomponent systems. By this means, the interaction parameter X for a polymer‐solvent system is defined using the well known Flory‐Huggins equation. The concentration dependent Gibbs free energy of mixing is used as a criterion for the relative compatibility of the PVC‐plasticizer system. The method indicates that, for the plasticizers examined, DOS is the least compatible and DBP is the most compatible with PVC. This confirms the results of the glass transition width measured by dynamic mechanical analysis previously reported.
Fundamental Study on Latent Cold Heat Energy Storage by Means of Oil Droplets at Low Freezing Point. Cold Heat Energy Release Characteristics of Direct-Contact Heat Exchange between Solidified Oil Droplets and Hot Air. (1997)

This paper deals with the cold latent heat energy release characteristics of direct-contact heat exchange between solidified oil droplets[tetradecane, CH3(CH2)12CH3, melting point of 5.8°C]and hot air. The hot air was injected into a solidified oil droplets-water mixture layer from the distributor with a number of small circular nozzles. The solidified oil droplets-water mixture layer was fluidized by air bubbles ascending in the layer, and the air bubbles were cooled as they passed through the layer, by direct-contact heat exchange. The present paper describes the characteristics of temperature and humidity of the outlet air from the layer, and time history of the cold heat energy release. The experiments were performed with reference to several experimental parameters, i.e., air flow rate, air temperature and humidity, and the proportion of solidified oil droplets to water in the mixture layer. Finally, some correlation equations for the outlet air temperature and humidity, and the completion time of cold latent heat energy release were derived in terms of various nondimensional parameters.
Systemic AA Amyloidosis Caused by Inflammatory Hepatocellular Adenoma (2018)

International audience
Synthesis of Thermoresponsive Glycopolymers Combining RAFT Polymerization, Thiol‐Ene Reaction, and Subsequent Immobilization onto Solid Supports (2014)

A new monomer, N ‐hexenylacrylamide, is copolymerized with N ‐isopropylacrylamide by reversible addition‐fragmentation chain transfer (RAFT) polymerization using a carboxylic‐acid‐functionalized RAFT agent. Subsequently, the resulting functional copolymers are reacted with acetylated thiogalactose via a thiol‐ene reaction. After deprotection of the sugar acetyl groups, the glycopolymers show a lower critical solution temperature (LCST) behavior, as confirmed by turbidity measurements. One of these glycopolymers is subsequently immobilized onto solid supports. The obtained products are characterized by attenuated total reflection Fourier transform IR (ATR FTIR) spectroscopy, thermal gravimmetric analysis (TGA), and elemental analysis, confirming the immobilization of the glycopolymer. Additionally, the glycopolymer‐functionalized support shows interaction with the lectin RCA 120 . image