gebhart/patrepeval huggingface dataset:
Preparation of a hydroxyethyl–titanium dioxide–carboxymethyl cellulose hydrogel cage and its effect on the removal of methylene blue (2017)

ABSTRACT A novel TiO 2 hydrogel cage model was built for the removal of methylene blue (MB), an organic pollutant. This TiO 2 hydrogel cage was prepared with the biomass materials of hydroxyethyl cellulose (HEC) and carboxymethyl cellulose (CMC), and this hydrogel cage structure was characterized by scanning electron microscopy, transmission electron microscopy, and X‐ray diffraction. The contents of the encased TiO 2 and its swelling properties with different CMC proportions of this hydrogel cage were studied to obtain a suitable crosslinking network structure and optimal synthesis conditions. Compared to an equivalent amount of pure TiO 2 , the much higher removal efficiency of MB with our prepared TiO 2 hydrogel cage was attributed to the synergistic effect of the photocatalytic degradation for TiO 2 and the adsorption enrichment for cellulose hydrogels. Furthermore, the adsorption kinetics of the intraparticle diffusion model were used to study the adsorption enrichment process of the TiO 2 hydrogel cage. In addition, on the basis of the results of photocatalytic degradation and recycling experiments, excellent performances with respect to self‐cleaning, regenerative ability, and easy recovery, were shown for this HEC–TiO 2 –CMC cage material, which demonstrated ideal application potential for MB removal. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017 , 134 , 44925.
Thin film retardation plate by oblique deposition (1989)

The birefringent property of obliquely deposited metal oxides was studied with a view to applying it to optical retardation plates. By finding favorable conditions to form transparent films of large retardation and low opacity, we developed homogeneous quarterwave plates with a bilayered structure 60 x 250 mm in size and ~3 microm thick on glass substrates. These retardation plates can work with a normally incident light based on form birefringence caused by the characteristic anisotropic microstructure inside the film. They showed promising optical properties which can compete with the conventional types of retardation plate.
Microvascular blood flow resistance: role of endothelial surface layer (1997)

Observations of blood flow in microvascular networks have shown that the resistance to blood flow is about twice that expected from studies using narrow glass tubes. The goal of the present study was to test the hypothesis that a macromolecular layer (glycocalyx) lining the endothelial surface contributes to blood flow resistance. Changes in flow resistance in microvascular networks of the rat mesentery were observed with microinfusion of enzymes targeted at oligosaccharide side chains in the glycocalyx. Infusion of heparinase resulted in a sustained decrease in estimated flow resistance of 14-21%, hydrodynamically equivalent to a uniform increase of vessel diameter by approximately 1 micron. Infusion of neuraminidase led to accumulation of platelets on the endothelium and doubled flow resistance. Additional experiments in untreated vascular networks in which microvascular blood flow was reduced by partial microocclusion of the feeding arteriole showed a substantial increase of flow resistance at low flow rates (average capillary flow velocities < 100 diameters/s). These observations indicate that the glycocalyx has significant hemodynamic relevance that may increase at low flow rates, possibly because of a shear-dependent variation in glycocalyx thickness.
Processing Gain Advantage of Transform Domain Filtering DS - Spread Spectrum Systems (1982)

This paper presents a new perspective on the performance of so-called transform domain filtering spread spectrum communication systems. Considering a direct sequence system operating in the presence of narrowband interference, it is demonstrated by how much a conventional spread spectrum system would have to increase its processing gain (and hence its rf bandwidth) in order to provide the same degree of interference rejection as the transform domain filtering system.
Collision avoidance system for fixed obstacles-fuzzy controller network for robot driving of an autonomous vehicle (2002)

A Collision Avoidance System (CAS), which overrules the driver in a critical situation, by steering and/or braking has to be better and more reliable than the driver himself. The driving maneuver is complex and difficult to calculate by traditional mathematical models. Therefore, an ACC car with extended sensors for object detection and a human driver were taken in order to get the data how the driver avoids the Collision with a fixed object in the driving lane. Afterwards, this data was used in order to develop a fuzzy controller network of full collision avoidance for fixed objects. The effectiveness and the robustness of the more than 300 rules of the Fuzzy Controller Network were tested by using the same ACC car, but driven by a robot on the driver seat. The result of these tests are presented in this paper.
Wood char gasification chemical kinetics in mixtures of CO2 and H2O (2002)

A small-scale stratified downdraft gasifier has been built and operated under stable conditions using wood pellets as fuel and air as gasification agent. The problems observed during the preliminary experiments have been described and explained; they are mainly related to the stability of the process. The stable operation of the gasifier has been characterised by the gas composition and the product gas tar and particle content. The biomass feeding rate has varied between 4,5 and 6,5 kg/h. The CO content of the product gas (23-26 % vol.) is higher than in similar gasifiers and the H2 content has been found to vary between 14 and 16 % vol. The tar content in the product gas (ca. 3 g/Nm3) is rather high compared with similar gasifiers. The temperature profile, together with other relevant parameters like the air-excess ratio, the air to fuel ratio and gas to fuel ratio have been calculated. The experiments show that the air excess ratio is rather constant, varying between 0,25 and 0,3. Experiments have been conducted with a gas engine using mixtures of CH4, CO, H2, CO2 and N2 as a fuel. NOx and CO emissions are analysed. The char gasification process has been studied in detail by means of Thermogravimetric Analysis. The study comprises the chemical kinetics of the gasification reactions of wood char in CO2 and H2O, including the inhibition effect of CO and H2. A kinetic model based on Langmuir-Hinshelwood kinetics has been found which relates the mass loss rate to the temperature, gas composition and degree of conversion for each reaction. The ratio CO/CO2 has been found to be a relevant parameter for reactivity. The gasification experiments in mixtures of CO2 and H2O give reasons to believe that the rate of desorption for the complex C(O) varies depending on the gas mixture surrounding the char. It has been found that if the experimental data are obtained from separate H2O/N2 and CO2/N2 experiments, the reactivity of the char in mixtures of CO2 and H2O can be fairly predicted.
Synthesis and Order of Assembly of Spore Coat Proteins in Bacillus subtilis (1981)

Analysis of mature spores or their integuments by extraction with sodium dodecyl sulphate/dithioerythritol followed by electrophoresis shows that the coat contains four major proteins and about ten others. Nine of the 14 proteins begin to be synthesized in stage II or stage III and their synthesis must be controlled by stage II or stage III operons. Some of these proteins are incorporated into the spore structure from about t 4 onwards (i.e. 4 h after induction of sporulation). Their deposition in the coat between t 4 and t 7 is not stopped by chloramphenicol, with the exception of one protein (mol. wt 36000) which begins to be synthesized only at t 6. Spores were isolated at various stages from about t 5 onwards, and the surface proteins were labelled with 125I. The labelling patterns show that proteins which are exposed on the surface at t 5·3 are successively overlaid as the spores mature. It appears that the coat of the mature spore contains at least three layers. The outermost layer is mainly composed of an alkali-soluble protein (mol. wt 12 000), which is synthesized early (t 2), and the 36000 mol. wt protein, which is synthesized very late. Deposition of the former seems to require processing by proteolytic action, and both proteins are apparently necessary for the acquisition of resistance to lysozyme, though not for resistance to heat or organic solvents. The results are discussed in relation to the classification of sporulation events and the nomenclature of the genetic loci controlling sporulation.
THE DEMOGRAPHY OF ETHNOGRAPHY (1995)

In concluding our term as editors, we review the submissions we have received over the last eight years and offer some insight into recent demographic trends in the field of ethnography, including who is conducting research, how they are doing it, and where they are focusing their attention. We compare these findings to previous speculations and assumptions, and to demographic trends in the field more generally. We also offer an analysis of the standards by which reviewers assessed articles submitted and the characteristics of articles that were likely to yield various dispositions.
Prediction of rotor slotting harmonics in induction machines in the presence of air-gap eccentricity (2015)

The paper analyses the influence of induction machine (IM) design on rotor slotting harmonics used for sensorless control strategies. These harmonics have a direct impact on flux and rotor position estimation accuracy. Therefore prediction of their magnitude helps in selecting suitable machine designs with regard to stator/rotor slotting and winding configuration. The paper at hand focuses on the effects that lead to the formation of the rotor slotting harmonic, by analyzing them with a simplified inductance phasor model, finite element (FE) simulations and measurement results. These three means are used to prove the existence of certain machine slotting and winding configurations that result in rotor slotting harmonic mitigation, or even complete cancelation. As will be shown, the magnitude of this mitigation effect is directly linked to a fault induced asymmetry originating from mixed (static and dynamic) rotor eccentricity within the machine.
Цифровые резервы телевидения (2002)

Digital aspect of analog TV connected with the problems of creating single TV system of high and standard sharpness is analyzed. The ways of transition from analog to digital TV taking into account the advantages of digital methods is considered but digital equipment necessary for their realization hasn’t been created yet.
50-gene risk profiles in peripheral blood predict COVID-19 outcomes: A retrospective, multicenter cohort study (2021)

This work was supported in part by National Institute for Health Research Clinician Scientist Fellowship NIHR: CS-2013-13-017 (TMM); Action for Pulmonary Fibrosis Mike Bray fellowship (PLM); The National Heart, Lung, and Blood Institute (NHLBI) through award K01-HL-130704 (AJ); The University of South Florida (USF) Academic Support Fund and the USF Foundation, Ubben Fibrosis Fund (JHM).
Homocoupling for Pentalenes Synthesis (2009)

The authors describe a general method for the synthesis of substituted penta­lenes. This is a straightforward alternative to existing pyrolitic or multistep synthetic approaches.
Transcriptome analysis of dominant-negative Brd4 mutants identifies Brd4-specific target genes of small molecule inhibitor JQ1 (2017)

The bromodomain protein Brd4 is an epigenetic reader and plays a critical role in the development and maintenance of leukemia. Brd4 binds to acetylated histone tails and activates transcription by recruiting the positive elongation factor P-TEFb. Small molecule inhibitor JQ1 competitively binds the bromodomains of Brd4 and displaces the protein from acetylated histones. However, it remains unclear whether genes targeted by JQ1 are mainly regulated by Brd4 or by other bromodomain proteins such as Brd2 and Brd3. Here, we describe anti-proliferative dominant-negative Brd4 mutants that compete with the function of distinct Brd4 domains. We used these Brd4 mutants to compare the Brd4-specific transcriptome with the transcriptome of JQ1-treated cells. We found that most JQ1-regulated genes are also regulated by dominant-negative Brd4 mutants, including the mutant that competes with the P-TEFb recruitment function of Brd4. Importantly, JQ1 and dominant-negative Brd4 mutants regulated the same set of target genes of c-Myc, a key regulator of the JQ1 response in leukemia cells. Our results suggest that Brd4 mediates most of the anti-cancer effects of JQ1 and that the major function of Brd4 in this process is the recruitment of P-TEFb. In summary, our studies define the molecular targets of JQ1 in more detail.
Time-of-flight secondary ion mass spectrometry imaging of dopant diffusion in optical fiber (2003)

Time-of-flight secondary ion mass spectrometry imaging of dopant diffusion in optical fiber
Cloud Computation Based Urban Management System Using Ros (2019)

Due to rapid urbanization, the pollution and global warming are increasing at very higher rate. The greenery must maintain to minimize the effect of pollution and global warming. The management of waste should done in an efficient manner. Water level of the nearby rivers should monitor frequently to ameliorate the effect of floods. Smart street light systems are required to reduce the wastage of electricity. This research work proposes a development of novel IOT based application called twilio, which implemented using ROS. It facilitates the central processing unit to monitor and control the various sensor modules and send appropriate alerts to the mobile phone through SMS service. In this research work, we are automating watering greeneries, minimizing the wastage of water, monitoring the waste in dustbins, sending alerts during the emergencies like floods and fire accidents and implementing the smart street light system using SMS service.
Use of Wavelet Transform to Detect Compensated and Decompensated Stages in the Congestive Heart Failure Patient (2017)

This research work is aimed at improving health care, reducing cost, and the occurrence of emergency hospitalization in patients with Congestive Heart Failure (CHF) by analyzing heart and lung sounds to distinguish between the compensated and decompensated states. Compensated state defines stable state of the patient but with lack of retention of fluids in lungs, whereas decompensated state leads to unstable state of the patient with lots of fluid retention in the lungs, where the patient needs medication. Acoustic signals from the heart and the lung were analyzed using wavelet transforms to measure changes in the CHF patient's status from the decompensated to compensated and vice versa. Measurements were taken on CHF patients diagnosed to be in compensated and decompensated states by using a digital stethoscope and electrocardiogram (ECG) in order to monitor their progress in the management of their disease. Analysis of acoustic signals of the heart due to the opening and closing of heart valves as well as the acoustic signals of the lungs due to respiration and the ECG signals are presented. Fourier, short-time Fourier, and wavelet transforms are evaluated to determine the best method to detect shifts in the status of a CHF patient. The power spectra obtained through the Fourier transform produced results that differentiate the signals from healthy people and CHF patients, while the short-time Fourier transform (STFT) technique did not provide the desired results. The most promising results were obtained by using wavelet analysis. Wavelet transforms provide better resolution, in time, for higher frequencies, and a better resolution, in frequency, for lower frequencies.
Nanoporous molecular crystals (2010)

Nanoporous Molecular Crystals (NMCs) are nanoporous materials composed of discrete molecules between which there are only non-covalent interactions—i.e. they do not possess an extended framework composed of covalent or coordination bonds. They are formed from removing guest molecules from inclusion compounds (ICs) a process that for most ICs usually results in the collapse of the open structure of the crystals but in the case of NMCs the packing of the host molecules is retained and nanoporosity obtained. In recent years a number of NMCs have been confirmed by the technique of gas adsorption and these materials are surveyed in this feature article. In addition, the reasons for stability of these crystals are discussed. It is the author's belief that many more ICs, the structures of which are readily obtainable from the Cambridge Structural Database (CSD), may act as precursors to NMCs.
Five Years Later—What Have We Accomplished? (2005)

1Susan V. White, PhD RN CPHQ FNAHQ, is the associate chief of nursing/quality improvement at the James A. Haley VA Hospital, Tampa, FL. She is the interviews editor for JHQ and the co-editor of Patient Safety: Principles and Practices published by Springer in 2004. 2Christy L. Beaudin, PhD LCSW CPHQ FNAHQ, is the corporate director for quality improvement at PacifiCare Behavioral Health in Van Nuys, CA. She is editor of the recently released Q Solutions: Essential Resources for the Healthcare Quality Professional and is a member of JHQ's editorial board.
Acetic Acid and Lactic Acid Inhibition of Growth ofSaccharomyces Cerevisiaeby Different Mechanisms (2001)

Two strains of Saccharomyces cerevisiae were grown in minimal medium with glucose as the carbon source and with added acetic acid or lactic acid. The intracellular pH (pHi) of yeast cells was not significantly affected by acetic acid up to a concentration of 0.25% w/v. The pHi was maintained at a more or less constant value through increased activity of plasma membrane H+-adenosinetriphosphatase (H+-ATPase), which pumps out protons. With lactic acid at a concentration of 0.4% w/v or higher, the pHi dropped enough to affect yeast growth. This drop in pHi was the result of reduced activity of membrane-bound H+-ATPase. Cell membrane lipids of yeast cells grown in the presence of 0.5% w/v lactic acid contained considerably reduced levels of the two unsaturated fatty acids palmitoleic and oleic. Changes in the fatty acid composition of cells grown with acetic acid were relatively small. These differences in internal pH, plasma membrane H+-ATPase activities, and membrane fatty acid composition all indicate that acetic and lactic acids inhibit the growth of S. cerevisiae by different mechanisms.
Early invasive vulvar squamous cell carcinoma arising in a woman with vulvar pemphigus vulgaris and systemic lupus erythematosus (2010)

Our case underlines PV as another chronic inflammatory disease of the lower genital tract predisposing to VIN-SCC. It suggests the need for careful follow-up of patients with chronic inflammatory disease, especially when concomitant autoimmune disorders are present. Moreover, a biopsy should be always performed if there are PV lesions because of the possibility of neoplastic disease.
Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet–Biedl syndrome (2015)

Compartmentalization and polarized protein trafficking are essential for many cellular functions. The photoreceptor outer segment (OS) is a sensory compartment specialized for phototransduction, and it shares many features with primary cilia. As expected, mutations disrupting protein trafficking to cilia often disrupt protein trafficking to the OS and cause photoreceptor degeneration. Bardet-Biedl syndrome (BBS) is one of the ciliopathies associated with defective ciliary trafficking and photoreceptor degeneration. However, precise roles of BBS proteins in photoreceptor cells and the underlying mechanisms of photoreceptor degeneration in BBS are not well understood. Here, we show that accumulation of non-OS proteins in the OS underlies photoreceptor degeneration in BBS. Using a newly developed BBS mouse model [Leucine zipper transcription factor-like 1 (Lztfl1)/Bbs17 mutant], isolated OSs, and quantitative proteomics, we determined 138 proteins that are enriched more than threefold in BBS mutant OS. In contrast, only eight proteins showed a more than threefold reduction. We found striking accumulation of Stx3 and Stxbp1/Munc18-1 and loss of polarized localization of Prom1 within the Lztfl1 and Bbs1 mutant OS. Ultrastructural analysis revealed that large vesicles are formed in the BBS OS, disrupting the lamellar structure of the OS. Our findings suggest that accumulation (and consequent sequestration) of non-OS proteins in the OS is likely the primary cause of photoreceptor degeneration in BBS. Our data also suggest that a major function of BBS proteins in photoreceptors is to transport proteins from the OS to the cell body or to prevent entry of non-OS proteins into the OS.
Optimization of in vitro transcription/translation conditions for in vitro compartmentalization studies and synthesis of 4-fluorohistidine (2017)

Genetic code expansion allows the incorporation of non-canonical amino acids with a variety of new functional groups: fluorescent amino acids,1-3 azides,4-6 alkynes,5-10 and photocrosslinkers.4,11,12 This incorporation requires the evolution of new tRNA/aminoacyl tRNA sythetase pairs. Traditionally screenings of novel tRNA/aminoacyl tRNA synthetase pairs have been done in vivo. While these in vivo screenings have proven robust, they are limited in multiple ways: non-canonical amino acids (ncAAs) must be nontoxic and bioavailable. Furthermore, library size is limited by transformation efficiency. Lastly, in vivo screenings require substantial amounts of the target ncAA, which is often not available in large masses. In vitro screenings bypass these limitations: toxicity and bioavailibilty are no longer concerns. Library size can be expanded by several orders of magnitude as we are no longer limited by transformation efficiency. Lastly, because in vitro transcription/translation reactions are routinely conducted on the μL scale, ncAA usage can be minimized. We set out to use in vitro compartmentalization to further expand the code. In an in vitro compartmentalization screening, the water droplets in a water-in-oil emulsion serve as separate reaction chambers in which individual library members are transcribed and translated. Here we report optimization of S30 transcription/translation reactions. Optimizations include cell lysis method, reaction temperature, template amount, and T7 RNA polymerase amounts. Yields remained low and we transistioned into the use of PURExpress. Fluorohistidines are isosteric with histidine, but not isoelectronic.13 This change in environment results in a reduction of pKa. We set out to synthesize 4-fluorohistidine to use as a pH probe in several target proteins. A synthesis of 4-fluorohistidine was published in 1973.14,15 We were able to improve upon this synthesis by reducing cost and improving yield of a key step in the reaction. Next, small peptides with polyhistidine tags were translated in vitro using our 4-fluorohistidine. We are calling this polyhistidine tag incorporating 4-fluorohistidine our “hexafluorohistag.” Because of the reduced pKa of the 4-fluorohistidine, the hexafluorohistag showed affinity to Nickel-NTA resin even at reduced pH. This allowed for the purification of hexafluorohistagged peptides in the presence of traditional polyhistidine-tagged peptides.