gebhart/patrepeval huggingface dataset:
Spectrally Resolved Microscopy of GFP Trafficking (2002)

Folding and chromophore cyclization-oxidation processes of green and cyan fluorescent fusion proteins (GFP and CFP) in subcellular microenvironments of transfected C6 glioma cells were studied by multipixel spectrally resolved microscopy (SRM). Discrete time-dependent spectral transitions were characterized during protein folding and chromophore maturation in the cytosol, nucleus, mitochondria, endoplasmic reticulum (ER), and Golgi. Spectral similarity mapping of fluorophore transition phases demarcated spatio-temporal fluorescence correlation at a subcellular level. Folding stages were characterized by a transition from red-shifted spectral populations in the time interval of 7-10 hr after transfection to a fully matured fluorophore emitting typical GFP or CFP fluorescence after 10-15 hr. The nascent protein revealed an initial focal accumulation in cytosol emitting in the range of 580-680 nm. After 10 hr, mixed pixel population spectra were measured and at 15 hr GFP was visualized in the cytoplasm by its specific spectral fingerprints with maxima at 545 nm. For nucleus- and mitochondrion-targeted CFPs, the mature conformer was discovered only in its final destination, whereas intermediate steps of fluorophore synthesis (at 10 hr) were found in the cytoplasm. Enhanced fluorescence maturation was manifested only by the ER-Golgi-targeted CFP after 10 hr post transfection by spectral imaging. Moreover, only remnants of initial intermediate fluorescent pixels were localized externally to the Golgi framework at 15 hr. SRM assessed the competence of ER-Golgi to maintain efficient CFP folding in comparison to the rest of the cellular compartments.
Surface plasmon resonance-induced visible light photocatalytic reduction of graphene oxide: Using Ag nanoparticles as a plasmonic photocatalyst (2011)

The present communication reports on the first preparation of reduced graphene oxide (rGO) via surface plasmon resonance (SPR)-induced visible light photocatalytic reduction of GO with the use of Ag nanoparticles (AgNPs) as a plasmonic photocatalyst in the presence of an electron donor (ED).
The Prediction of Helicopter Rotor Hover Performance using a Prescribed Wake Analysis (1976)

A method of calculating the performance of a helicopter rotor in the hover is presented. The method combines the downwash velocity distribution induced by a contracting spiral vortex wake with strip element-momentum theory. The shape of the wake takes a prescribed geometry developed from an extensive series of model tests made in the USA. The predicted thrust and power is in good agreement with measurements made on model and full scale rotors provided that the aerofoil data is sufficiently well defined. The calculated load distribution along the blade is also compared with measurements made on Wessex helicopters. The load distribution is shown to be very sensitive to a light wind but theory compares well with experiment when this effect is eliminated. The hover performance predicted using only the wake induced velocity distribution is also discussed. The rotor performance is shown to be too sensitive to the geometry of the wake for the method to be used as a design tool with confidence, and the mathematical representation of the wake needs improving.
Photonic crystal waveguides with semi-slow light and tailored dispersion properties (2006)

We demonstrate a concept for tailoring the group velocity and dispersion properties for light propagating in a planar photonic crystal waveguide. By perturbing the holes adjacent to the waveguide core it is possible to increase the useful bandwidth below the light-line and obtain a photonic crystal waveguide with either vanishing, positive, or negative group velocity dispersion and semi-slow light. We realize experimentally a silicon-on-insulator photonic crystal waveguide having nearly constant group velocity ~c(0)/34 in an 11-nm bandwidth below the silica-line.
[(CH3)2NH2]7Pb4X15 (X = Cl– and Br–), 2D-Perovskite Related Hybrids with Dielectric Transitions and Broadband Photoluminiscent Emission (2018)

We have prepared two new lead halides with the novel general formula of DMA<sub>7</sub>Pb<sub>4</sub>X<sub>15</sub> (DMA = [(CH<sub>3</sub>)<sub>2</sub>NH<sub>2</sub>]<sup>+</sup> and X = Cl<sup>-</sup> or Br<sup>-</sup>) by using an easy route under mild conditions at room temperature. These compounds exhibit an unprecedented crystal structure, are formed by layers of distorted [PbX<sub>6</sub>] octahedra, which share corners and faces, and contain intercalated DMA cations. Very interestingly, they display dielectric transitions, which are related to a partial order-disorder process of the DMA cations between 160 and 260 K. Additionally, these new layered hybrids exhibit a broadband photoluminiscent emission, which is related to the structural distortions of the [PbX<sub>6</sub>] octahedra. These findings not only open up large possibilities for future optoelectronic applications of these materials, but they also offer a novel playground for an easy modulation of electrical and optical properties of hybrid organic-inorganic materials. We anticipate that this novel A<sub>7</sub>Pb<sub>4</sub>X<sub>15</sub> formula can be adequate to tune the family of the hybrid lead halides using other alkylammonium cations, such as methylammonium, formamidinium, or ethylammonium, to improve their photoelectronic properties.
Cumulative Dynamic Inter-Core Skew Measurements in Spooled Uncoupled Core Multicore Fibers (2022)

We measured the propagation delay fluctuations and dynamic inter-core skew of 125 µm cladding, 4-core fibers with 15.7, 29.5, and 50 km lengths. The measurements provide insight on the skew dependence on transmission distance.
Modeling and Analysis of Piezoelectric Energy Harvesting From Aeroelastic Vibrations Using the Doublet-Lattice Method (2010)

Multifunctional structures are pointed out as an important technology for the design of aircraft with volume, mass, and energy source limitations such as unmanned air vehicles (UAVs) and micro air vehicles (MAVs). In addition to its primary function of bearing aerodynamic loads, the wing/spar structure of an UAV or a MAV with embedded piezoceramics can provide an extra electrical energy source based on the concept of vibration energy harvesting to power small and wireless electronic components. Aeroelastic vibrations of a lifting surface can be converted into electricity using piezoelectric transduction. In this paper, frequency-domain piezoaeroelastic modeling and analysis of a cantilevered platelike wing with embedded piezoceramics is presented for energy harvesting. The electromechanical finite-element plate model is based on the thin-plate (Kirchhoff) assumptions while the unsteady aerodynamic model uses the doublet-lattice method. The electromechanical and aerodynamic models are combined to obtain the piezoaeroelastic equations, which are solved using a p-k scheme that accounts for the electromechanical coupling. The evolution of the aerodynamic damping and the frequency of each mode are obtained with changing airflow speed for a given electrical circuit. Expressions for piezoaeroelastically coupled frequency response functions (voltage, current, and electrical power as well the vibratory motion) are also defined by combining flow excitation with harmonic base excitation. Hence, piezoaeroelastic evolution can be investigated in frequency domain for different airflow speeds and electrical boundary conditions.
Promoter region of the bovine growth hormone receptor gene: Single nucleotide polymorphism discovery in cattle and association with performance in Brangus bulls1 (2008)

Expression of the GH receptor (GHR) gene and its binding with GH is essential for growth and fat metabolism. A GT microsatellite exists in the promoter of bovine GHR segregating short (11 bp) and long (16 to 20 bp) allele sequences. To detect SNP and complete an association study of genotype to phenotype, we resequenced a 1,195-bp fragment of DNA including the GT microsatellite and exon 1A. Resequencing was completed in 48 familialy unrelated Holstein, Jersey, Brown Swiss, Simmental, Angus, Brahman, and Brangus cattle. Nine SNP were identified. Phylogeny analyses revealed minor distance (i.e., <5%) in DNA sequence among the 5 Bos taurus breeds; however, sequence from Brahman cattle averaged 27.4 +/- 0.07% divergence from the Bos taurus breeds, whereas divergence of Brangus was intermediate. An association study of genotype to phenotype was completed with data from growing Brangus bulls (n = 553 from 96 sires) and data from 4 of the SNP flanking the GT microsatellite. These SNP were found to be in Hardy-Weinberg equilibrium and in phase based on linkage disequilibrium analyses (r(2) = 0.84 and D'= 0.92). An A/G tag SNP was identified (ss86273136) and was located in exon 1A, which began 88 bp downstream from the GT microsatellite. Minor allele frequency of the tag SNP was greater than 10%, and Mendelian segregation was verified in 3 generation pedigrees. The A allele was derived from Brahman, and the G allele was derived from Angus. This tag SNP genotype was a significant effect in analyses of rib fat data collected with ultrasound when bulls were ~365 d of age. Specifically, bulls of the GG genotype had 6.1% more (P = 0.0204) rib fat than bulls of the AA and AG genotypes, respectively. Tag SNP (ss86273136), located in the promoter of GHR, appears to be associated with a measure of corporal fat in Bos taurus x Bos indicus composite cattle.
Adaptive minimum bit-error rate equalization for binary signaling (2000)

We consider the design and adaptation of a linear equalizer with a finite number of coefficients in the context of a classical linear intersymbol-interference channel with Gaussian noise and a memoryless decision device. If the number of equalizer coefficients is sufficient, the popular minimum mean-squared-error (MMSE) linear equalizer closely approximates the optimal linear equalizer that directly minimizes bit-error rate (BER). However, when the number of equalizer coefficients is insufficient to approximate the channel inverse, the minimum-BER equalizer can outperform the MMSE equalizer by as much as 16 dB in certain cases. We propose a simple stochastic adaptive algorithm for realizing the minimum-BER equalizer. Compared to the least-mean-square algorithm, the proposed algorithm can provide a substantial reduction in BER with no increase in complexity.
Norfloxacin-Poly(l-Lysine Citramide Imide) Conjugates and Structure-dependence of the Drug Release (2004)

Norfloxacin (Nflx), an antibiotic which is active against some intracellular bacteria, was coupled to a polymeric carrier, namely poly(L-lysine citramide) via a lysine or an ethylcarbamate spacer to obtain a macromolecular prodrug. The carrier, which derived from the two metabolites citric acid and L-lysine, is known to be biocompatible and slowly degradable under slight acidic conditions. Conjugates were characterised by UV, 1H and 13C NMR and SEC. The presence of Norfloxacin and the lysine type spacer caused chain aggregation, due to a probable physical cure. The release of Norfloxacin from these prodrugs and from a prodrug where Norfloxacin is bound to the carrier backbone without spacer arm was investigated comparatively in vitro. Conjugation via a carbamate-type linkage appeared as a method to achieve the release of Norfloxacin from a PLCA-type conjugate at neutral.
Der Histondeacetylase-Inhibitor Valproinsäure induziert Apoptose in humanen Hepatomzellen, jedoch nicht in primären humanen Hepatozyten (2004)

Hepatozelluläre Karzinome (HCC) weisen erfahrungsgemäß eine ausgeprägte Resistenz gegenüber Chemotherapeutika auf. Vor kurzem konnte durch eine Modifikation DNA-assoziierter Histonproteine mit Substanzen aus der Klasse der Histondeacteylase-Inhibitoren (HDAC-I) eine Proliferationshemmung mit nachfolgendem Zelltod von HCC Zellen beschrieben werden. Hierfür verantwortliche Mechanismen sind, bis auf eine Hyperacetylierung von Histonen, nur unvollständig verstanden. Unklar ist auch, wie HDAC-I auf gesunde, nicht-maligne Hepatozyten wirken. Die wichtigste Voraussetzung um dieses Therapieprinzip für einen zukünftigen klinischen Einsatz beim HCC nutzbar zu machen, stellt die Verfügbarkeit einer gut verträglichen Substanz mit definiertem Nebenwirkungsprofil dar.
Stardust: Compiling Sparse Tensor Algebra to a Reconfigurable Dataflow Architecture (2022)

We introduce Stardust, a compiler that compiles sparse tensor algebra to reconfigurable dataflow architectures (RDAs). Stardust introduces new user-provided data representation and scheduling language constructs for mapping to resource-constrained accelerated architectures. Stardust uses the information provided by these constructs to determine on-chip memory placement and to lower to the Capstan RDA through a parallel-patterns rewrite system that targets the Spatial programming model. The Stardust compiler is implemented as a new compilation path inside the TACO open-source system. Using cycle-accurate simulation, we demonstrate that Stardust can generate more Capstan tensor operations than its authors had implemented and that it results in 138$\times$ better performance than generated CPU kernels and 41$\times$ better performance than generated GPU kernels.
3201 An SPC Approach to Quality Visualization for Factor Analysis in PCB Mounting Process (2009)

In printed circuit board (PCB) mounting process using surface mount technology (SMT), automated optical inspection systems (AOI) are widely employed in order to guarantee the process quality such as volume of printed solder paste and size of soldered solder joint. However, a quality control method using the quality characteristics measured by AOI has not been established. We developed a statistical quality control (SPC) system which displays the variation of quality characteristics in a two dimensional color graph. It enables the analyzer to instantly narrow down the factors by recognizing the condition in which the quality anomaly occurs. We implemented the system to a PCB mounting factory and succeeded in reducing the cycle time of the process improvement and preventing soldering defect as a result.
Comparing Kidney Perfusion Using Noncontrast Arterial Spin Labeling MRI and Microsphere Methods in an Interventional Swine Model (2010)

Cortical perfusion measured with ASL correlated with microspheres and reliably detected changes in renal perfusion in response to physiologic challenge.
Overpressure history of fractures, West Maracaibo Basin, Venezuela (1996)

Prediction of density of natural fractures in reservoir rocks requires evaluation of many factors, including the effective stress and thus fluid pressure conditions through time. In this study we use analyses of fluid inclusions in calcite-filled fractures with burial and thermal history models to assess the fluid pressure history and the causes of overpressure in the West Maracaibo Basin. We analyzed abundant oil-filled and rare aqueous fluid inclusions in calcite-filled fractures in the La Luna Formation source rock and in the underlying Cogollo Gp. carbonate reservoir. Our analyses of fluid inclusion homogenization temperatures and fluorescence properties lead us to the interpretation of near-lithostatic paleo-fluid pressures in La Luna Formation and near-lithostatic to hydrostatic fluid pressures in the Cogollo, Gp. fractures. Maturation and expulsion of oil from the La Luna Formation source rock is required to generate the large inferred excess pressures as compaction disequilibrium and thermal expansion of pore fluids from rapid Miocene burial are insufficient to achieve near-lithostatic conditions. This hypothesis is supported by the observation of decreasing paleo- and modern fluid pressures with depth beneath the La Luna Formation. Thus based on the wide occurrence of oil-filled inclusions in calcite-filled fractures and the high fluid pressures associated withmore » trapped oils, we infer extensive rock fracture under overpressured conditions near maximum Miocene burial, during inferred late source rock yield, and during Miocene growth of structural traps.« less
Implantable Hearing Devices (2009)

Four types of implantable hearing devices exist, each with its specific indication.


Cochlear implants (CI) are intended for severe to profound sensorineural hearing loss. Patients implanted at a young age may achieve speech and language skills comparable to normal hearing children.


Bone-anchored hearing aids (BAHA) are intended for conductive hearing loss not amenable to reconstruction or amplification, and for single-sided deafness. Children are usually implanted in two stages.


Implantable middle ear devices (IMED) are currently not approved for children. They are intended for moderate to moderately severe sensorineural hearing loss.


Auditory brainstem implants (ABI) are indicated for profoundly deaf patients with an abnormal cochleae or cochlear nerves who are not otherwise candidates for CI. In the USA, only children above 12 years of age with neurofibromatosis type 2 (NF2) are approved for ABI.
Murine myeloid progenitor responses to GM‐CSF and eosinophil precursor responses to IL‐5 represent distinct targets for downmodulation by prostaglandin E2 (2000)

1. Because Prostaglandin E(2) (PGE(2)) and dibutiryl cyclic AMP (dbcAMP) modulate the production and effects of haemopoietic cytokines in allergy, we examined their ability to modulate responses of myeloid progenitors to GM-CSF, and of eosinophil precursors to IL-5. 2. The ability of PGE(2), dbcAMP, rolipram, forskolin, dbcGMP and PGD(2), to modulate the responses to GM-CSF and IL-5 in colony formation (progenitor) and eosinophil differentiation (precursor) assays using bone-marrow from nonsensitized or from intranasally-challenged, ovalbumin-sensitized mice of five strains was studied. 3. PGE(2) (10(-7) M) inhibited GM-CSF-stimulated colony formation in bone-marrow from BP-2 mice. This effect was duplicated by dbcAMP (0.3 - 1x10(-6) M), Rolipram (10(-5) M) and forskolin (3x10(-5) M), but not Prostaglandin D(2) (10(-6) M). Inhibition affected similarly all myeloid colony types. Progenitors from sensitized and challenged BP-2 mice were also inhibited by PGE(2) and cyclic AMP. PGE(2) inhibited progenitors from C57BL/10, CBA/J and A/J, but not BALB/c mice. However, BALB/c progenitors were sensitive to dbcAMP and Forskolin (10(-4) M). In contrast, in precursor assays, PGE(2) (10(-7) - 10(-9) M) blocked responses to IL-5 in bone-marrow from BP-2 and BALB/c mice, either naïve or sensitized and challenged, to a similar extent. PGD(2) (10(-6) M) was ineffective, as was PGE(2) (10(-7) M), if added after 48 h of culture. 4. In conclusion, PGE(2) inhibits the responses of bone-marrow myeloid progenitors to GM-CSF and of eosinophil precursors to IL-5, in naïve or ovalbumin sensitized and challenged mice. These effects are duplicated by cyclic AMP-elevating agents. In the BALB/c strain, the resistance of progenitors, but not precursors, to PGE(2) inhibition, indicates these developmental stages are separate targets for PGE(2) modulation.
Suppression of water‐layer multiples — from deconvolution to wave‐equation approach (2000)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 2000Suppression of water‐layer multiples — from deconvolution to wave‐equation approachAuthors: Dmitri LokshtanovDmitri LokshtanovNorsk Hydro Research Centre, Bergenhttps://doi.org/10.1190/1.1815825 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1815825FiguresReferencesRelatedDetailsCited byLand Seismic Multiples Detection and Attenuation In Bornu-Chad Basin, Nigeria5 January 2021 | Pakistan Journal of Geology, Vol. 4, No. 2Resolving Shallow Reef Effect with New Water Layer Demultiple Method and Diving Wave Tomography: A Case Study from South China Sea22 March 2019Shallow water demultiple in complex water bottom area, a case study from South China SeaZheng Liu, Ming Zhu, Jiao He, Rong Li, and Sherman Yang11 December 2018Seismic preprocessing and amplitude cross-calibration for a time-lapse amplitude study on seismic data from the Oseberg reservoirGeophysical Prospecting, Vol. 53, No. 2 SEG Technical Program Expanded Abstracts 2000ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 2000 Pages: 2484 publication data© 2000 Copyright © 2000 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished Online: 04 Jan 2005 CITATION INFORMATION Dmitri Lokshtanov, (2000), "Suppression of water‐layer multiples — from deconvolution to wave‐equation approach," SEG Technical Program Expanded Abstracts : 1981-1984. https://doi.org/10.1190/1.1815825 Plain-Language Summary PDF DownloadLoading ...
Rheumatic fever–associated Streptococcus pyogenes isolates aggregate collagen (2003)

Acute rheumatic fever is a serious autoimmune sequel of Streptococcus pyogenes infection. This study shows that serotype M3 and M18 S. pyogenes isolated during outbreaks of rheumatic fever have the unique capability to bind and aggregate human basement membrane collagen type IV. M3 protein is identified as collagen-binding factor of M3 streptococci, whereas M18 isolates bind collagen through a hyaluronic acid capsule, revealing a novel function for M3 protein and capsule. Following in vivo mouse passage, conversion of a nonencapsulated and collagen-binding negative M1 S. pyogenes into an encapsulated, collagen-binding strain further supports the crucial role of capsule in mediating collagen binding. Collagen binding represents a novel colonization mechanism, as it is demonstrated that S. pyogenes bind to collagen matrix in vitro and in vivo. Moreover, immunization of mice with purified recombinant M3 protein led to the generation of anti–collagen type IV antibodies. Finally, sera from acute rheumatic fever patients had significantly increased titers of anti–collagen type IV antibodies as compared with healthy controls. These findings may suggest a link between the potential of rheumatogenic S. pyogenes isolates to bind collagen, and the presence of collagen-reactive autoantibodies in the serum of rheumatic fever patients, which may form a basis for post-streptococcal rheumatic disease. These anti-collagen antibodies may form a basis for poststreptococcal rheumatic disease.
Green house and field evaluation of transgenic wheat overexpressing AVP1, NAS2 and PSTOL1 genes for higher grain yield (2020)

Phenotypic and climate/environment data collected for IWYP39 field and glasshouse trials conducted in 2017 by the Unversity of Adelaide, South Australia. Rainfall data for the field trial was collected at Glenthorne Farm, O'Halloran Hill, South Australia and reported by Martin Carson. Climate data provided for the field trial was collected at the Adelaide Airport, South Australia, and reported by the Australian Government, Bureau of Meteorology. Climate and growth environment data for the glasshouse study was collected and reported by The Plant Accelerator, Waite Campus, Urrbrae, South Australia. Greenhouse data consisted of various phenotypic measurements taken periodically for AVP1, NAS2 and PSTOL1 single genes and pyramided lines (461 lines). The Field data consisted of phenotypic measurements for AVP1 and NAS2 single genes (280 lines).
Trapping Set Analysis of Finite-Length Quantum LDPC Codes (2021)

Iterative decoders for finite length quantum low-density parity-check (QLDPC) codes are impacted by short cycles, detrimental graphical configurations known as trapping sets (TSs) present in a code graph as well as symmetric degeneracy of errors. In this paper, we develop a systematic methodology by which quantum trapping sets (QTSs) can be defined and categorized according to their topological structure. Conventional definition of a TS from classical error correction is generalized to address the syndrome decoding scenario for QLDPC codes. We show that QTS information can be used to design better QLDPC code and decoder. For certain finite-length QLDPC codes, frame error rate improvements of two orders of magnitude in the error floor regime are demonstrated without needing any post-processing steps.