gebhart/patrepeval huggingface dataset:
Analysis of 3rd-order passive intermodulation generated from metallic materials (2008)

Passive Intermodulation (PIM) is caused by weak nonlinearity in a passive circuit, which has been discussed as interference in high-power microwave base-station systems. While PIM has such a negative aspect, it is applicable positively to finding defected contacts. This paper proposes a modified FDTD method involving current-mode nonlinearity. A technique to reduce the computation time using a linear calculation is also proposed. Although the study is limited to order 3 for a basic examination, validity of the proposed method is confirmed through an experiment using the open-ended coaxial method.
The Inside of Metal Calixarene Chemistry (2008)

Abstract Calixarene molecules are often associated with their ability to form inclusion complexes with organic or inorganic guests. These complexes are usually formed due to the guest molecule interactions with the calixarene aromatic cavity and/or substituents attached to it. The present mini-review discusses a different type of calixarene inclusion complexes, where the inclusion event occurs due to the coordination of an organic or inorganic ligand to a metal centre attached to the lower rim of calix[4]arene. Structural and chemical properties of such complexes of 'uninvited' guests are discussed. Keywords: CalixareneMetal complexesInclusion chemistryCoordination compounds
The Phoneme Identification Test for Assessment of Spectral and Temporal Discrimination Skills in Children: Development, Normative Data, and Test‐Retest Reliability Studies (2017)

The PIT normative data show that the ability to identify phonemes based on changes in formant transitions improves with age, and that some children in the general population have performance much worse than their age peers. In children, uncertainty increases when the stimuli are presented in noise. The test is suitable for use in planned studies in a clinical population.
Management of cavernous sinus meningiomas (1985)

The management of intracavernous meningiomas remains controversial. The variety of methods of treatment reflects the difficulty of treating primary meningiomas of the cavernous sinus. Twelve personal cases and a review of the literature permit a choice between a direct surgical approach with or without radiotherapy, only radiation therapy or with no therapy. We think therefore that meningiomas of the cavernous sinus should nowadays be the subject of a surgical biopsy followed by radiotherapy according to their grading.
Bulk plasmon polariton based structured illumination microscopy by utilizing hyperbolic metamaterials (2021)

Abstract Because structured illumination microscopy (SIM) has the advantages of wide-field, rapid imaging, and biocompatibility, it is widely used for super-resolution imaging of living cells. Here, we demonstrate a new super-resolution imaging method—bulk plasmon polariton based SIM (BPPSIM), which combines the SIM with the hyperbolic metamaterials (HMMs). By utilizing an HMM composed of a multilayer metal/dielectric film, a deep subwavelength bulk plasmon polariton is obtained. The imaging resolution of BPPSIM can be improved by the uniform and wide-field structured illumination pattern with high spatial frequency, benefiting from the filtering effect of HMM for the spatial frequency spectrum. The resolution of the recovered images by BPPSIM has been increased to 1/8 of the fluorescence wavelength, which is 2.7-fold enhancement in resolution compared with traditional fluorescence microscopy. This proposed approach demonstrates the operability and flexibility of the structured illumination pattern and can be used in a simple, wide-field and super-resolution fluorescence microscope.
Improved Measures for the Shape of a Disordered Polymer To Test a Mean-Field Theory of Collapse (2011)

We have generated off-lattice self-avoiding random walks (SAWs) by both Lal’s pivot algorithm and by discontinuous molecular dynamics (DMD) simulations. We chose several volume measures to analyze and compare the shapes characterizing ensembles of SAWs. These included the Flory volume defined through the end-to-end distance, the volume corresponding to the radius of gyration of the polymer, the volume of a sphere drawn from the center of polymer mass that encloses or embeds all the monomers in the polymer, the corresponding ellipsoid describing the radius of gyration tensor, the volume of the smallest Cartesian box oriented in a fixed “lab” frame which encloses all polymer monomers, and the volume of the smallest box oriented along the principal axes of the radius of gyration tensor that encloses all polymer monomers. The tensor ellipsoid and principal box correlate well with each other but not with the other measures. There is a substantial amount of polymer that is excluded from the radius of gyration sphere or ellipsoid (approximately 42% and 44% respectively on average), which casts doubt on the utility of these measures in quantitatively characterizing the volume spanned by a polymer configuration. The principal box volume led to the most well-defined length distribution for the SAW in terms of the ratio of standard deviation to the mean, while the end-to-end distribution was the most broadly distributed. In the principal box analysis, polymer configurations are highly anisotropic, with stronger cubic to square prism symmetry breaking than square prism to rectangular cuboid. We introduce the acubicity in analogy with the asphericity and find its distribution, along with a generalization of acubicity that better discriminates polymer anisotropy. We analyze the role of the above volume measures in determining the packing fraction which enters into the “random mixing” mean-field theory for the energy of an isolated homopolymer. Here we find from both pivot and DMD simulations that no particular volume measure reproduces the mean-field scaling exponent (of unity) for the energy as a function of the reciprocal polymer volume. Instead, anomalous exponents are observed which are less than that of mean-field theory, ranging from 0.2 to 0.5 depending on the contact cutoff length. An energy function with such an anomalous scaling may be used in a simple phenomenological theory of coil–globule collapse. We find in particular that the Flory volume does not accurately describe the energy in a mean-field theory. Possible reasons for such anomalous exponents are discussed.
Numerical Simulation of Biological Structures (2008)

IASS-IACM 2008 Session: Numerical Simulation of Biological Structures -- Session Organizer: Wilkins AQUINO (Cornell University) -- Keynote Lecture: "Computational modeling of glucose distribution in hollow fiber membrane bioreactors" by G.U. UNIKRISHNAN, V.U. UNIKRISHNAN, J.N. REDDY (Texas A and M University) -- "Characterization of viscoelastic properties of cylindrical vessels using the velocity response produced by an impulsive force" by Daniel E. ROSARIO, Wilkins AQUINO (Cornell University) -- "Solid versus membrane finite elements in analysis of the mitral valve: A case study" by Victorien PROT , Bjorn SKALLERUD (Norwegian University of Science and Technology) -- "An inverse problem approach for elasticity imaging through vibroacoustics" by Miguel AGUILO, Wilkins AQUINO (Cornell University) -- "Proper orthogonal decomposition model reduction for inverse problems in acoustic-structure interaction" by John C. BRIGHAM, Wilkins AQUINO (Cornell University) -- "Shell analysis of elliptical guard cells in higher plants: A review" by J. Robert COOKE , Richard RAND (Cornell University), Herbert MANG (TU Vienna), Josse DeBAERDEMAEKER (Katholieke Universiteit Leuven), Jae Young LEE (Chonbuk National University) -- "In vivo ultrasound bone property determination through inverse finite element modeling" by Mija HUBLER , Wilkins AQUINO, Christopher EARLS (Cornell University) -- "Finite element analyses of palm leaf petiole-sheath junctions in simple bending and twisting and in dynamic (oscillatory) flexure" by Karl NIKLAS , J. Robert COOKE (Cornell University), Jae Young LEE (Chonbuk National University) -- "Modeling pipette aspiration of biological membranes" by Philip BUSKOHL (Cornell University) -- "A new model for nucleation in two-phase lipid bilayer membrane vesicles" by Sanjay DHARMAVARAM , Timothy HEALEY (Cornell University)
Securing a Community Cloud (2010)

Virtual Interacting Network CommunIty (Vinci) is a software architecture that exploits virtualization to secure a community cloud, i.e. a cloud system shared among communities with distinct security levels and reliability requirements. A community consists of a set of users, their applications, a set of services and of shared resources. Users with distinct privileges and applications with distinct trust levels belong to distinct communities. Rather than acquiring and managing its own physical infrastructure, a community defines a virtual ICT infrastructure, i.e. an overlay, by instantiating and interconnecting virtual machines (VMs) defined from a small set of templates. Vinci includes templates to run user applications, protect shared resources and control traffic among communities to filter out malware or distributed attacks. The adoption of alternative VM templates minimizes the complexity of each VM and increases the robustness of both the VMs and of the overall infrastructure. The resulting overlays are mapped onto the cloud infrastructure or, from another perspective, they access an infrastructure service. The cloud provider defines a further overlay that interconnects VMs to manage the infrastructure resources and configure the VMs at start-up.
Systematic Production of Horticultural Plants by Microcomputer (1993)

パーソナルコンピュータで動作するバーコードリーダを使い，園芸生産での利用場面を検討した．ページプリンタを使用して印字したバーコードの認識精度が最も高く，ドットプリンタでの精度は劣った．バーコード利用による3つの経営管理システムを作成した．作業内容や土壌のpH・ECを管理するための生産管理システム，出荷・管理用のラベルの印刷や送り状の整理に利用できる出荷管理システム，直売において販売や残品の整理に利用できる直売管理システムを作成した．
Membrane Bound IgE: The Key Receptor to Restrict High IgE Levels (2008)

The membrane form of immunoglobulins (mIg) is expressed on the surface of B lymphocytes from a very early developmental stage in the bone marrow (pre B cell) until the cell finally differentiates into a plasma cell. mIgs associate with other transmembrane proteins to form the B cell antigen receptor complex (BCR). Numerous studies have confirmed that signaling through the BCR not only steers the B cell through development, but also ensures its survival in the periphery as a fully matured cell. During development in the bone marrow, mIg is restricted to the IgM isotype, but as soon as the B cell leaves the bone marrow to populate peripheral lymphoid organs like spleen, lymph nodes, or intestinal mucosal tissue, it starts to express IgD and in later stages of maturation IgG, IgE and IgA. Engagement of the B cell receptor triggers signals that control affinity maturation, memory induction, differentiation and other physiological processes in B cells. We showed that truncation of the cytoplasmic tail of mIgE in vivo results in lower serum IgE levels, decreased numbers of IgE-secreting plasma cells, and abrogation of specific secondary responses correlating with a defect in the selection of high-affinity antibodies during the germinal centre reaction. We conclude that the BCR is necessary at all times during antibody responses not only for the maturation process, but also for the expansion of antigen specific B cells. As a result of these findings it is obvious that the IgE antigen receptor could be a useful target molecule for therapeutic intervention.
A research on the new Demand Responsive Transit service in Japan (2009)

This paper proposes practical Demand Responsive Transit (DRT) system with a new reservation processing called “Insured Announced Time Reservation System (IATRS)”. DRT service has been expected as an alternative mode in public transportation which aims to improve mobility in a city. However, it was initially impractical because the routing system cannot assure reserved passengers that vehicles will arrive at the passengers’ destination by the announced arrival time. The developed IATRS for this new DRT service intends to ensure the announced arrival time by employing a slack time variable and a new proposed algorithm. The program composes of vehicle-choosing and routing algorithms. The vehicle-choosing algorithm decides which vehicle will accept the new reservation, while the routing algorithm designs the new route and schedule for the vehicle chosen to serve the new reservation. The system calculates and updates the route of the vehicle and returns the pick-up time to the customers immediately during reservation. Moreover, the vehicle will not delay the announced arrival time of passengers who have reserved already even if new passengers are added and the schedule of the vehicle is updated. In order to validate the proposed DRT service, one experiment was conducted in Kashiwa City, Japan in 2008. In the experiment in Kashiwa City, which is recognized as a commuters’ town of Tokyo metropolitan area, 3851 passengers used the about five DRT vehicles in 40 days (480 hours). It was shown that the characteristics of this system worked very well, and more than 44.7 percent of passengers were satisfied with the DRT service because they can make a reservation via personal computers and they were able to specify dependable arrival time or pick-up time. And 36.1 percent of passengers answered that their chances of going out increased by the introduction of DRT service. The result of Willingness To Pay (WTP) analysis is more than twice of fixed bus (353 yen / ride). In conclusion, the result of experiment showed the developed DRT service is a practical alternative mode for public transportation.
The novel nematicide wact-86 interacts with aldicarb to kill nematodes (2017)

Parasitic nematodes negatively impact human and animal health worldwide. The market withdrawal of nematicidal agents due to unfavourable toxicities has limited the available treatment options. In principle, co-administering nematicides at lower doses along with molecules that potentiate their activity could mitigate adverse toxicities without compromising efficacy. Here, we screened for new small molecules that interact with aldicarb, which is a highly effective treatment for plant-parasitic nematodes whose toxicity hampers its utility. From our collection of 638 worm-bioactive compounds, we identified 20 molecules that interact positively with aldicarb to either kill or arrest the growth of the model nematode Caenorhabditis elegans. We investigated the mechanism of interaction between aldicarb and one of these novel nematicides called wact-86. We found that the carboxylesterase enzyme GES-1 hydrolyzes wact-86, and that the interaction is manifested by aldicarb's inhibition of wact-86's metabolism by GES-1. This work demonstrates the utility of C. elegans as a platform to search for new molecules that can positively interact with industrial nematicides, and provides proof-of-concept for prospective discovery efforts.
Altered cutaneous immune parameters in transgenic mice overexpressing viral IL-10 in the epidermis (2003)

IL-10 is a pleiotropic cytokine that inhibits several immune parameters, including Th1 cell-mediated immune responses, antigen presentation, and antigen-specific T cell proliferation.Recent data implicate IL-10 as a mediator of suppression of cell-mediated immunity induced by exposure to UVB radiation (280-320 nm).To investigate the effects of IL-10 on the cutaneous immune system, we engineered transgenic mice that overexpress viral IL-10 (vIL-10) in the epidermis.vIL-10 transgenic mice demonstrated a reduced number of I-A + epidermal and dermal cells and fewer I-A + hapten-bearing cells in regional lymph nodes after hapten painting of the skin.Reduced CD80 and CD86 expression by I-A + epidermal cells was also observed.vIL-10 transgenic mice demonstrated a smaller delayed-type hypersensitivity response to allogeneic cells upon challenge but had normal contact hypersensitivity to an epicutaneously applied hapten.Fresh epidermal cells from vIL-10 transgenic mice showed a decreased ability to stimulate allogeneic T cell proliferation, as did splenocytes.Additionally, chronic exposure of mice to UVB radiation led to the development of fewer skin tumors in vIL-10 mice than in WT controls, and vIL-10 transgenic mice had increased splenic NK cell activity against YAC-1targets.These findings support the concept that IL-10 is an important regulator of cutaneous immune function.
Application of hybrid organic/inorganic polymers as coatings on metallic substrates (2016)

Acrylic polymers, particularly poly (methyl methacrylate) (PMMA), have certain specific properties, such as good film formation, transparency, and good mechanical properties, which have been widely used in paints, coatings and adhesives. However, the limited chemical and physical stability of these pure polymers limits their applications when exposed to hostile conditions, as in ship hulls, for example. A suitable way to enhance PMMA properties is the addition of silicon polymers with very good protective characteristics. In this study, a PMMA and HTT 1800 (commercial silazane) copolymer were applied on metallic substrate and compared to pure PMMA and HTT 1800. All the materials were applied as coatings. They were applied on stainless steel via dip-coating to investigate the coating properties. Thermal cycling was employed to analyze coating durability at high temperatures (50 °C to 600 °C). Optical microscopy (OM) and scanning electron microscopy (SEM) were used to characterize the coated surfaces, and the adhesion of pure PMMA, pure HTT 1800 and PMMA/HTT 1800 coatings on metallic substrate was investigated by Cross-Cut-Test (ASTM D 3359). The sessile drop method was used to determine the contact angle. PMMA coatings presented complete degradation from 250 °C, while hybrid coatings of PMMA and HTT 1800 have good protection until 400 °C. The adherence of the coating on metallic substrate showed improvement in all synthesized materials when compared to pure PMMA, obtaining the best adherence possible. The contact angle test showed that the hydrophobicity of the hybrid coatings is higher than that of the pure coatings.
Characterization of Platelet-Derived Growth Factor-A Expression in Mouse Tissues Using a lacZ Knock-In Approach (2014)

Expression of the platelet-derived growth factor A-chain gene (Pdgfa) occurs widely in the developing mouse, where it is mainly localized to various epithelial and neuronal structures. Until now, in situ mRNA hybridization (ISH) has been the only reliable method to identify Pdgfa expression in tissue sections or whole mount preparations. Validated protocols for in situ detection of PDGF-A protein by immunohistochemistry is lacking. In particular, this has hampered understanding of Pdgfa expression pattern in adult tissues, where ISH is technically challenging. Here, we report a gene targeted mouse Pdgfa allele, Pdgfaex4COIN, which is a combined conditional knockout and reporter allele. Cre-mediated inversion of the COIN cassette inactivates Pdgfa coding while simultaneously activating a beta-galactosidase (lacZ) reporter under endogenous Pdgfa transcription control. The generated Pdgfaex4COIN-INV-lacZ allele can next be used to identify cells carrying a Pdgfa null allele, as well as to map endogenous Pdgfa expression. We evaluated the Pdgfaex4COIN-INV-lacZ allele as a reporter for endogenous Pdgfa expression patterns in mouse embryos and adults. We conclude that the expression pattern of Pdgfaex4COIN-INV-lacZ recapitulates known expression patterns of Pdgfa. We also report on novel embryonic and adult Pdgfa expression patterns in the mouse and discuss their implications for Pdgfa physiology.
Graph2Seq: Scalable Learning Dynamics for Graphs (2018)

Neural networks have been shown to be an effective tool for learning algorithms over graph-structured data. However, graph representation techniques---that convert graphs to real-valued vectors for use with neural networks---are still in their infancy. Recent works have proposed several approaches (e.g., graph convolutional networks), but these methods have difficulty scaling and generalizing to graphs with different sizes and shapes. We present Graph2Seq, a new technique that represents vertices of graphs as infinite time-series. By not limiting the representation to a fixed dimension, Graph2Seq scales naturally to graphs of arbitrary sizes and shapes. Graph2Seq is also reversible, allowing full recovery of the graph structure from the sequences. By analyzing a formal computational model for graph representation, we show that an unbounded sequence is necessary for scalability. Our experimental results with Graph2Seq show strong generalization and new state-of-the-art performance on a variety of graph combinatorial optimization problems.
4-Nitroaniline-2-Sulfonic Acid Preparation and Salt Formation. A New Class of Aphrogens (1971)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT4-Nitroaniline-2-Sulfonic Acid Preparation and Salt Formation. A New Class of AphrogensAlgirdas C. PoshkusCite this: Ind. Eng. Chem. Prod. Res. Dev. 1971, 10, 1, 72–75Publication Date (Print):March 1, 1971Publication History Published online1 May 2002Published inissue 1 March 1971https://pubs.acs.org/doi/10.1021/i360037a014https://doi.org/10.1021/i360037a014research-articleACS PublicationsRequest reuse permissionsArticle Views104Altmetric-Citations4LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Nanoparticle Lung Delivery and Inhalation Aerosols for Targeted Pulmonary Nanomedicine (2013)

Nanomedicine drug-delivery systems have a number of advantages1−3: (1) to achieve relatively uniform distribution of drug dose; (2) to enhance the apparent solubility of a poorly water-soluble drug; (3) to control drug release that can consequently reduce the dosing frequency; (4) to achieve macromolecule delivery of therapeutic proteins and polypeptides; (5) to reduce sideCONTENTS3.1 Introduction ..................................................................................................43 3.2 Anatomy of the Human Respiratory Tract and InhalationAerosol Particle Deposition ........................................................................45 3.3 Respiratory Diseases and Targeted Pulmonary Nanomedicine...........48