gebhart/patrepeval huggingface dataset:
정신보건 : 정서행동문제아동을 위한 아이존 공동 프로그램 개발에 관한 연구 (2014)

연구목적：본 연구는 서울시 아동청소년정신보건시설인 아이존이 확대됨에 따라 저소득층 정서 행동문제아동을 위한 아이존의 표준적인 서비스 프로그램을 구축하기 위하여 수행되었다. 연구방법：연구1에서는 아동용 집단프로그램 중, 사회성 증진프로그램(또래기술 훈련)과 심리정서 증진 프로그램(자존감 향상, 분노조절 훈련), 그리고 부모교육 집단프로그램을 선정하여 각 프로그램에 참여한 실험집단과 대기 중인 통제집단 간에 유의한 차이가 있는지 비교하였다. 연구 2에서는 송파아이존 프로그램에 대한 효과검증 결과를 토대로 하여, 아이존 공동프로그램을 확정한 뒤, 다른 세 곳 아이존을 포함한 총 4곳 아이존에서 동시에 공동프로그램을 진행하였다. 연구결과：결과적으로, 아이존 공동으로 진행한 아동 및 부모용 집단프로그램에서 모두 유의한 결과를 보였다. 결 론：본 연구는 근거에 기반하여 아이존의 공통적인 집단 프로그램의 기틀을 마련하는데 기여했다고 본다. 아이존의 지속적인 발전을 위해서는 이용아동의 특성에 맞는 심화된 프로그램을 개발하고, 효과검증 연구를 통해 서비스 프로그램의 질과 다양성을 유지하려는 노력이 요구된다.
Inbreeding Effects on Hatchery and Growout Performance of Pacific White Shrimp, Penaeus (Litopenaeus) vannamei (2008)

Abstract In animal breeding programs, selection coupled with a narrow genetic base can cause high levels of inbreeding to occur rapidly (in one or two generations). Although the effects of inbreeding have been studied extensively in terrestrial animals and to a lesser extent in aquaculture species, little is known about the effects of inbreeding on penaeid shrimp. The objective of this study was to investigate the effects of inbreeding on hatchery and growout performance of the Pacific white shrimp, Penaeus vannamei . The experiment was conducted over 2 yr, and data from two successive generations (G 2 and G 3 ) of inbred (sibling–sibling mating) and outbred families were analyzed. There were 11 inbred and 12 outbred families in G 2 and 9 inbred and 10 outbred families in G 3 . Inbreeding coefficients ( F ) for outbred and inbred families were 0.00 and 0.25, respectively, for G 2 and 0.00 and 0.375, respectively, for G 3 . Growth rates for outbreds and inbreds were similar in both G 2 and G 3 . Hatch rate for inbred families was 33.1% lower than for outbred families in G 2 and 47.1% lower in G 3 . Inbreeding depression (IBD) (relative change in phenotype per 0.1 increase in F ) ± 95% CI for hatch rate was −12.3 ± 10.1%. Hatchery survival for inbred families was 31.4% lower than for outbred families in G 2 and 38.8% lower in G 3 . IBD for hatchery survival was −11.0 ± 5.7%. Growout survival was 1.9% lower for inbred families than for outbred families in G 2 and 19.6% lower in G 3 . IBD for growout survival was −3.8 ± 2.9%. There was also a significant linear relationship between IBD estimates for survival traits and mean outbred survival. At high outbred survival, IBD was low (e.g., growout survival in G 2 ), but IBD appeared to become more severe when outbred survival was lower. This suggests that stress (related to environment and/or life stage) may worsen IBD for survival traits. Results also indicate that moderate to high levels of inbreeding (&gt;10%) should be avoided in commercial shrimp hatcheries because the cumulative effect of IBD on hatch rate and hatchery survival will significantly reduce postlarvae production. Thus, IBD can be significant enough to justify the use of inbreeding as a germplasm protection strategy (under certain scenarios) for genetic improvement programs.
Shape- and size-selective photocatalytic reactions by layered titanic acid powder suspended in deaerated aqueous alcohol solutions (2000)

Protonic titanate of HxTi2−x/4Zx/4O4 ·H2O (HLe; x≃0.7, Z = vacancy) powder of a layered crystal structure was prepared, suspended in aqueous alcoholic solutions and photoirradiated by light of wavelength >300 nm at room temperature under a deaerated atmosphere. HLe showed photocatalytic activity of H2 production, similar to ordinary titanium(IV) oxide powders. The rate and time course of H2 evolution by HLe depended strongly on the kind of alcohol. Detailed investigation revealed that the photocatalytic activity was regulated by the shape and size of the alcohol, due to the selection of adsorption at the interlayer of HLe.
Wound recurrence following conventional treatment of colorectal cancer (1996)

Incisional recurrence is uncommon, although likely underestimated, following conventional treatment of colorectal carcinoma. Its occurrence is usually a harbinger of diffuse intra-abdominal disease. These data may provide useful information for investigations of laparoscopic approaches to colon cancer.
IAV single-virus tracking on A549 cells. (2020)

&lt;p&gt;Single virus tracking on live A549 cells revealed four main types of virus movement: (&lt;b&gt;A&lt;/b&gt;) three-stage movement, (&lt;b&gt;B&lt;/b&gt;) confined, (&lt;b&gt;C&lt;/b&gt;) mixed, (&lt;b&gt;D&lt;/b&gt;) drift. The fraction of all modes of movement was analyzed at the indicated conditions (&lt;b&gt;E&lt;/b&gt;).&lt;/p&gt; &lt;p&gt;(PDF)&lt;/p&gt;
Optical bistability in a nonlinear photonic crystal waveguide notch filter (2000)

Optical bistability occurs when the effects of nonlinear behaviour of materials cause hysteresis in the transmission and reflection of a device. A possible mechanism for this is a strong dependence of the optical intensity on the index of refraction, e.g. in a cavity near resonance. In a 2-dimensional photonic crystal composed of rods of high-index material in air, a waveguide can be created by removing a line of rods. When a cavity is made by taking away several rods perpendicular to the waveguide, a notch filter characteristic in the transmission occurs. Due to the high intensity in the cavity in resonance, nonlinear effects are enhanced. This paper shows numerical simulations of bistability in the transmission and in the field inside the cavity both when a material inside the cavity has third-order (Kerr-type) nonlinear effects, and when the high-index rods themselves are nonlinear.
Preparation and Characterization of Cu(II), Zn(II) Sulfides Obtained by Spontaneous Precipitation in Electrolyte Solutions (1998)

Transition metal sulfides, because of their electronic and spectroscopic properties, are a very interesting class of materials that may be used efficiently for the construction of photoelectric chemical solar cells. In the present work we have prepared a series of mixed Cu and Zn sulfides with the general stoichiometry CuxZn1-xS by coprecipitation in aqueous solutions. Precipitates with x = 0.10, 0.15, 0.20, 0.22, 0.25, and 0.50 were synthesized by mixing metal nitrates with ammonium sulfide at pH 2.50. The precipitates behaved as n-type semiconductors. The dependence of the conductivity of the materials on temperature and calculations of the thermoelectric power coefficient showed the presence of metallic conducting islands separated by nonconducting parts, for copper content corresponding to x = 0.15, 0.20, and 0.22. For x = 0.10, the precipitates behaved as insulators, whereas for x = 0.50, the precipitates showed metallic character. The morphology and the mean particle size of the precipitates varied with increasing Zn content, yielding for pure CuS, prismatic crystals with a mean size of ∼5 μm. Upon increasing Zn content, polycrystalline materials were obtained, forming aggregates of submicron, spherullitic particles. The measurements of the electrical properties of the materials showed that the conditions of precipitation play an important role for the design of their properties.
Action of some analogues of neurokinin A on the growth of skin and synovial fibroblasts in vitro (1990)

Conference Article| April 01 1990 Action of some analogues of neurokinin A on the growth of skin and synovial fibroblasts in vitro AHMED A. ABU SHANAB; AHMED A. ABU SHANAB *Department of Biochemistry, The Queen's University of Belfast, Belfast BT9 7BL, N, Ireland, U.K. Search for other works by this author on: This Site PubMed Google Scholar DAVID J. S. GUTHRIE; DAVID J. S. GUTHRIE *Department of Biochemistry, The Queen's University of Belfast, Belfast BT9 7BL, N, Ireland, U.K. Search for other works by this author on: This Site PubMed Google Scholar ANN E. HUGHES; ANN E. HUGHES †Department of Medical Genetics, The Queen's University of Belfast, Belfast BT9 7BL, N, Ireland, U.K. Search for other works by this author on: This Site PubMed Google Scholar RAYMOND A. B. MOLLAN; RAYMOND A. B. MOLLAN ‡Department of Orthopaedic Surgery, The Queen's University of Belfast, Belfast BT9 7BL, N, Ireland, U.K. Search for other works by this author on: This Site PubMed Google Scholar RICHARD F. MURPHY; RICHARD F. MURPHY *Department of Biochemistry, The Queen's University of Belfast, Belfast BT9 7BL, N, Ireland, U.K. Search for other works by this author on: This Site PubMed Google Scholar BRIAN WALKER BRIAN WALKER *Department of Biochemistry, The Queen's University of Belfast, Belfast BT9 7BL, N, Ireland, U.K. Search for other works by this author on: This Site PubMed Google Scholar Author and article information Publisher: Portland Press Ltd Received: September 18 1989 Online ISSN: 1470-8752 Print ISSN: 0300-5127 © 1990 Biochemical Society1990 Biochem Soc Trans (1990) 18 (2): 352. https://doi.org/10.1042/bst0180352 Article history Received: September 18 1989 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Citation AHMED A. ABU SHANAB, DAVID J. S. GUTHRIE, ANN E. HUGHES, RAYMOND A. B. MOLLAN, RICHARD F. MURPHY, BRIAN WALKER; Action of some analogues of neurokinin A on the growth of skin and synovial fibroblasts in vitro. Biochem Soc Trans 1 April 1990; 18 (2): 352. doi: https://doi.org/10.1042/bst0180352 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search Keywords: NKA, neurokinin A, Aib, aminoisobutyric acid, Nle, norleucine, MePhe, N-methylphenylalanine, Sar, sarcosine, Orn, ornithine, DMEM, Dulbecco's modified Eagles medium, PBS, phosphate-buffered saline © 1990 Biochemical Society1990 Article PDF first page preview Close Modal You do not currently have access to this content.
Association of Isolated Congenital Heart Disease with Fetal Brain Maturation (2020)

The fetal total maturation score is sensitive to differences in brain maturation between fetuses with isolated congenital heart disease and healthy controls.
A B cell riddle: a new tool to study the link between malaria and Burkitt’s Lymphoma (TUM5P.935) (2014)

Abstract Burkitt’s lymphomas (BLs) are B cell lineage tumors that are the most common childhood cancer in the P. falciparum malaria endemic areas of Africa. The molecular basis of malaria infection causing endemic BLs (eBLs) remains unknown. Recent data has confirmed that remarkably 30% of eBLs are enriched for one particular heavy chain V region, VH4-34. The US frequency in normal individuals is 4%, however it was unknown in endemic regions of Africa. This high frequency of VH4-34 in eBLs initiated the use of the anti-VH4-34 antibody, ‘9G4’, to study VH4-34 at the cellular level in Africa. Here we report that in adults and children living in a malaria endemic area of Mali, VH4-34 expressing B cells are present in frequencies similar to those in individuals in the U.S, however more B cells are found in memory B cell subpopulations. We have also found that VH4.34 circulating antibody levels increase when infected with malaria but do not significantly increase with age unlike other malaria specific antibodies. This suggests the VH4-34 heavy chain is possibly important for malaria, but is decreased from the repertoire after infection is controlled. We are initiating studies to determine: the frequency of VH4-34 expressing B cells latently infected with EBV to see if it enriched, whether VH4-34 Abs are protective in malaria, and elucidating a molecular mechanism for transformation. This data will start an avenue to better understand the complex mechanisms behind this childhood cancer.
Expression of the Rat Brain Creatine Transporter in situ and in Transfected HeLa Cells (1996)

Using degenerate oligonucleotide probes encoding conserved regions of the gamma-aminobutyric acid/norepinephrine transporter gene family, we have cloned a rat brain cDNA encoding a creatine transporter (rCREAT). rCREAT encodes a highly hydrophobic, 635-amino-acid protein possessing 12 potential transmembrane domains and canonical sites for N-linked glycosylation and protein phosphorylation. Transfection of rCREAT cDNA into mammalian cells results in the expression of [14C]creatine uptake, which is blocked by low micromolar concentrations of recognized creatine uptake inhibitors. Two rCREAT mRNAs are expressed in the rat brain, retina, kidney and heart. Whole-brain rCREAT mRNAs demonstrate a marked postnatal rise to steady-state adult levels. In situ hybridization studies indicate a widespread, differential rCREAT mRNA expression in adult rat brain, with high expression noted over myelinated fiber tracts, cerebellar granule cells, hippocampal pyramidal cells, brainstem nuclei and endothelial cells of the choroid plexus. These studies will allow the development of new molecular probes useful for defining the creatine transporter's cellular expression pattern, function in ATP homeostasis and association with disorders of cellular energy metabolism.
In-plane effective mass in narrow quantum wells of nonparabolic semiconductors (1993)

A formula is derived for the in-plane effective mass in narrow quantum wells, taking into account the effects of energy band nonparabolicity. The variation of the mass with the width of the well is studied by using the formula for four systems of wells. The mass is nearly the same as the velocity effective mass of the bulk material of the well in GaAs/Ga0.7Al0.3As wells. It is about 8% larger in InAs/InP wells, but is significantly larger in very narrow wells of Ga0.47In0.53As/InP systems. In the case of InAs/Ga0.58Al0.42Sb wells, the in-plane mass differs from the well mass by large amounts for all well widths of interest.
Frame Skeleton Based Auto-Inbetweening in Computer Assisted Cel Animation (2004)

Automatic inbetweening is one of the main focuses in computer assisted cel animation as inbetweening process is traditionally time-consuming and labor-intensive in the production of cartoon animation. Most previous work demand either lots of modeling or working with complicated programs and their interfaces, which do not take much animator's expertise into consideration, as animators are usually more capable of drawing pictures on the paper than programming with computer. An approach proposed in this paper aims to provide an easy-to-use system which automatically models key frames "on the fly " and interpolates them in several layers, including object size and position, line curvatures and curve texture in order to preserve artistic style of the hand-drawn key frames and make the motion smooth and natural. Without much user interaction and complicated program interface the system may be tuned, uploaded into the Web so that not only professional artists but those who are interested in cartoon but don't have much time or skill on drawing frames or inexperienced at using computer, like students, free-lance animators, etc. may benefit from using the system, for example, creating animation clips for the Web. The results show that the algorithm works well although it leaves areas for further research to extend and improve the algorithm to work with as many different types of key frames as possible.
A high-order compact formulation for the 3D Poisson equation (1996)

In this work we construct an extension to a class of higher-order compact methods for the three-dimensional Poisson equation. A superconvergent nodal rate of O(h6) is predicted, or O(h4) if the forcing function derivatives are not known exactly. Numerical experiments are conducted to verify these theoretical rates. © 1996 John Wiley & Sons, Inc.
Microbubble Contrast Agents (2006)

The use of microbubble contrast agents for general tissue delineation and perfusion enjoys steady interest in ultrasound imaging. Microbubbles as contrast materials require a small dosage and show excellent detection sensitivity. Targeting ligands on the surface of microbubbles permit the selective accumulation of these particles in the areas of interest, which show an up-regulated level of receptor molecules on vascular endothelium. Selective contrast imaging of inflammation, ischemia-reperfusion injury, angiogenesis, and thrombosis has been achieved in animal models. Ultrasound-assisted drug delivery and activation, performed by combining microbubble agent containing drug substances or coadministered with pharmaceutical agents (including plasmid DNA for transfection), has been achieved in multiple model systems in vitro and in vivo. Ultrasound and microbubbles-based targeted acceleration of the thrombolytic enzyme action already have reached clinical trials. Overall, microbubble targeting and ultrasound-assisted microbubble-based drug-delivery systems will offer a step toward the application of targeted personalized diagnostics and therapy.
Elbow Evaluation Via Telephone and Video Visit (2023)

Background Elbow conditions and pathology are commonly seen in the outpatient clinic. Telephone and video visits can allow for expeditious assessment of elbow complaints, without the added challenges of commuting for a clinic-based evaluation. In the setting of a pandemic, the benefits of telemedicine are apparent, but the time and effort saved from being able to remotely evaluate musculoskeletal conditions are also useful in a non-pandemic situation. In this modern era of telemedicine, protocols need to be developed to provide guidance for a remote elbow evaluation. As with all musculoskeletal conditions, the history about the elbow complaint allows the clinician to develop a differential diagnosis, which is either supported or refuted based on physical examination and diagnostic studies. Appropriate questions asked over a telephone call can provide answers that lead the clinician to a specific diagnosis and treatment plan. Furthermore, responses to these same questions can be further supported by a video assessment of the affected elbow, which may provide additional evidence to support a diagnosis and plan of care. Aims To outline possible questions, responses, and video examination techniques to aid the clinician in elbow examinations conducted via telemedicine. Methods We have created a pathway for step-by-step evaluation to help physicians direct their patients through the typical elements of a thorough elbow examination via telehealth. Results We have created tables of questions, answers, and instructions to help guide the physician through different aspects of a telehealth elbow examination. We have also included a glossary of descriptive images that demonstrate each maneuver. Conclusion This article provides a structured guide to efficiently extracting clinically relevant information during telemedicine examinations of the elbow.
Activation of p53 Function in Carcinoma Cells by the α6β4 Integrin (1999)

The interaction of integrins with extracellular matrix is known to promote cell survival by inhibiting apoptotic signaling. In contrast, we demonstrate here that the alpha6beta4 integrin induces apoptosis in carcinoma cells by stimulating p53 function. Specifically, we show that expression of alpha6beta4 in carcinoma cells that lack this integrin stimulates an increase in the transactivating function of p53 as demonstrated by the ability of this integrin to up-regulate the expression of a p53-sensitive reporter gene as well as the endogenous p53 response gene, bax. In addition, we report that alpha6beta4 triggers apoptosis in carcinoma cells that express wild-type but not mutant p53 and that these alpha6beta4 functions are inhibited by a dominant negative p53 construct. Importantly, we provide a link between integrin signaling and p53 activation by demonstrating that the clustering of alpha6beta4 with a beta4 integrin-specific antibody promotes p53-dependent apoptosis in cells that express both alpha6beta4 and wild-type p53. These studies are the first to demonstrate that a specific integrin can promote apoptosis by activating p53. Moreover, given the ability of alpha6beta4 to stimulate invasion (Shaw, L. M., Rabinovitz, I., Wang, H. F., Toker, A., and Mercurio, A. M. (1997) Cell 91, 949-960), these studies suggest that the ability of alpha6beta4 to promote carcinoma progression will be enhanced in tumor cells that express mutant, inactive forms of p53.
Improvement of Isotropic Strength of 3D Printing-Based Self-Healing Capsules by Controlling the Position of Holes (2022)

Self-healing capable of storing two or more solutions is proposed to heal cracks by manufacturing capsules with a 3D printer to enable structural design, repeatable fabrication, and strength analysis. The Fusion Deposition Modeling (FDM) method was used to design, analyze, and produce new, widely used self-healing capsules at low cost. However, since the PLA extruded from FDM has low interlayer adhesion energy, the strength varies depending on the load angle applied to the laminated surface and concrete structure, which degrades the performance of the self-healing capsule. Therefore, this paper designed a structure with isotropic strength by controlling the direction and number of solution injection ports of capsules manufactured by the FDM PLA method. In addition, the intensity isotropy of the load applied through the compression test and ANSYS in the x, y, and z directions were verified. As a result, as the arrangement and number of holes were different, the standard deviation of strength according to the direction decreased by 24%.
Can physical stress be measured in urine using the parameter antioxidative potential? (2010)

Although regular exercise is known to promote health, it is also well known that competetive sports can lead to an increase of free radical production, and thus to a drop in antioxidative potential. Thus, the present study examined the effect of competetive sports on the antioxidative potential (AOP). Using chemoluminescence, the AOP was measured in the spontaneous urine of leisure and semi-professional athletes during a training camp. Further, the parameters creatinin and uric acid were measured. It was shown that physical stress led to a drop in the antioxidant potential of up to approximately 50%. To compensate for this decline, special antioxidant food is recommended.
Development of a multi-frequency ESR system with high sensitivity (2006)

We have developed a new Multi-Frequency (MF) ESR system for the frequencies between 35 to 130 GHz utilizing TE011 single mode resonators. Their sensitivities (1010spins/G at 1.5 K) are comparable to that of a conventional low frequency ESR resonator and an order of magnitude higher than that of a Fabry Perot resonator which was previously developed by us. Thanks to a newly developed precise and stable matching system, we observed for the first time MFESR spectra of a metalloprotein with an integer spin.
Abstract 10612: Use of the AHA Pegasis Pipeline to Identify Genetic Associations With Severe 3-Vessel Coronary Artery Disease in High-Risk Pedigrees Free From Myocardial Infarction: The ProGENE Study (2019)

Introduction: To develop new strategies and medications to more precisely treat cardiac patients, it is critical to not only continue discovering genes that increase risk of disease, but also find ...