gebhart/patrepeval huggingface dataset:
Choledochoduodenal Fistula With Cholangitis and Duodenal Obstruction: A Rare Complication of Pancreatic Cancer Managed With Endoscopic Therapy (2014)

SymbolIntroduction: Pancreatic cancer is the fourth leading cause of cancer deaths in the United States. Formation of a spontaneous choledochodudodenal fistula (CDF) is rare with an estimated incidence of 3-5%. Self-expanding metal stents (SEMS) are commonly used to treat obstructive jaundice in patients with unresectable pancreatic head cancers. Spontaneous CDF can be caused by tumor invasion, bile duct stones, cholangitis, stent migration or chemoradiation and are usually managed surgically. We present the case of a patient with an advanced pancreatic head adenocarcinoma and a spontaneous CDF with cholangitis and duodenal obstruction managed endoscopically. A 67-yearold woman with unresectable pancreatic adenocarcinoma metastatic to the liver presented with RUQ abdominal pain, fever, hyperbilirubinemia, rigors, nausea and an inability to tolerate oral intake. PMHx is significant for chemoradiation and biliary SEMS placement 7 months prior. Diagnosis of acute cholangitis was made, and IV fluids and antibiotics were started. Upper endoscopy noted a large cavity with surrounding ulcer in the medial wall of the duodenum through which the mid portion of the previously placed metal CBD stent was visible consistent with a CDF. Severe luminal narrowing in the posterior duodenal bulb restricted access to the ampulla and conventional ERCP. APC and balloon dilation of the SEMS through the CDF were performed to access the obstructed biliary system. This technique is similar to EUS-guided choledochoduodenostomy. A plastic biliary stent was placed to relieve the biliary obstruction and cholangitis resolved. Surgical consultation deemed patient was not a surgical candidate due to advanced disease and poor nutritional status. Patient returned for endoscopy 3 days later. CDF tract widened with APC and a new SEMS placed through the fistulous tract. Ultrathin endoscope used to traverse narrowed duodenum and facilitate palliative duodenal stent placement. Patient’s symptoms resolved, nutritional status improved, and she was able to start a new course of palliative chemotherapy 1 week later. She was feeling well at 60 days of follow-up. In summary, cases of choledochoduodenal fistula, previous metal biliary stent placement, duodenal obstruction and cholangitis are rare complications of pancreatic cancer and can present a difficult management challenge in patients who are not candidates for surgical therapy. Endoscopic drainage of the obstructed biliary system can be accomplished by using APC and balloon dilation and then stenting through the CDF and may be a viable alternative to surgery.Symbol
Dual Emission, Aggregation, and Redox Properties of Boron Difluoride Hydrazones Functionalized with Triphenylamines (2022)

Abstract π‐Conjugated molecular materials often exhibit interesting photoluminescence, redox, and optoelectronic properties that grant them utility as light‐harvesting materials in solar cells, as the emissive component of organic light‐emitting diodes, and as fluorescence sensors. Preparing dye conjugates by appending multiple dyes together to generate π‐conjugated molecules is a common strategy to enhance the properties of these materials as it often imparts traits that cannot be achieved by the building blocks independently. Herein, we report molecular materials that incorporate boron difluoride hydrazone (BODIHY) and triphenylamine (TPA) units that exhibit charge‐transfer character, dual‐emission, and aggregation‐induced emission. The title compounds have low‐energy absorption bands (λ abs =455–493 nm) that are red‐shifted relative to BODIHYs with smaller π‐systems and exhibit dual‐emission in the solution, solid, and aggregate states. TPA–BODIHY (donor‐acceptor) conjugates show multiple reversible redox events and, in combination, the data presented herein indicate that there is electronic communication throughout the donor‐acceptor and acceptor‐donor‐acceptor π‐systems. These results are rationalized with the use of computational chemistry and solid‐state structural analysis. This study provides new opportunities for the design of molecular materials that are comprised of redox‐active photoluminescent dyes, including BODIHY, and their potential applications.
Research on CAD System Architecture Based on SOA and Web Service (2009)

In allusion to construct CAD system integrating based on the traditional technologies indicates some prominent problems; this paper brings forward Web service-based service-oriented architecture to integrate CAD system. According to the special task requirement and characteristic of design and analyses, we put forward a new approach for integrating CAD system to adopt Web service-based service-oriented architecture. And a service-oriented architecture of CAD system is given based on Web service. At the same time, This paper discusses some key technology and relating protocol standard. Finally, a CAD system architecture based on SOA and Web service is realized.
Phosphinoalkylsilanes: synthesis and spectroscopic properties of phosphino(silyl)methanes, 1-phosphino-2-silylethanes, and 1-phosphino-3-silylpropanes (1983)

Synthesis of thirty-three compounds Ph2P(CH2)nSiXYZ (n= 1, 2, or 3) and Me2P(CH2)2SiXYZ in which X, Y, or Z = H, Me, Ph, or Cl has been accomplished by (a) reaction at –78 °C in tetrahydrofuran between alkyl(chloro)silanes and Ph2PCH2Li·tmeda for n= 1, or (b u.v. irradiation of chloro(vinyl)silanes or allyl(chloro)silanes with Ph2PH or Me2PH for n= 2 or 3, with (c) reduction of the chlorosilyl products to Si–H analogues. Characterization of the phosphinoalkylsilane derivatives includes full 1H, 13C, and 31P n.m.r. data which are discussed in terms of dependence on the number of methylene groups, n, in the backbone and on the substituents, X, Y, Z, at Si, together with comparisons to related compounds.
Selection of Best Band Combination for Soil Salinity Studies using ETM + Satellite Images (A Case study: Nyshaboor Region,Iran) (2009)

� Abstract—One of the main environmental problems which affect extensive areas in the world is soil salinity. Traditional data collection methods are neither enough for considering this important environmental problem nor accurate for soil studies. Remote sensing data could overcome most of these problems. Although satellite images are commonly used for these studies, however there are still needs to find the best calibration between the data and real situations in each specified area. Neyshaboor area, North East of Iran was selected as a field study of this research. Landsat satellite images for this area were used in order to prepare suitable learning samples for processing and classifying the images. 300 locations were selected randomly in the area to collect soil samples and finally 273 locations were reselected for further laboratory works and image processing analysis. Electrical conductivity of all samples was measured. Six reflective bands of ETM + satellite images taken from the study area in 2002 were used for soil salinity classification. The classification was carried out using common algorithms based on the best composition bands. The results showed that the reflective bands 7, 3, 4 and 1 are the best band composition for preparing the color composite images. We also found out, that hybrid classification is a suitable method for identifying and delineation of different salinity classes in the area. Keywords—Soil salinity, Remote sensing, Image processing, ETM + , Nyshaboor
Prenatal diagnosis of Charcot‐Marie‐Tooth disease type 1a by multicolor in situ hybridization (1993)

Genetic heterogeneity within the most common genetic neuropathy, Charcot-Marie-Tooth disease (CMT) results in about 70% slow nerve conduction CMT1 and 30% normal nerve conduction CMT2. Autosomal dominant CMT1A on chromosome 17p11.2 represents about 70% of CMT1 cases and about 50% of all CMT cases. Three different size CMT1A duplications with variable flanking breakpoints were characterized by multicolor in situ hybridization and confirmed by pulsed field gel electrophoresis and quantitative polymerase chain reaction (PCR) amplification. These different size duplications result in the same CMT1A phenotype confirming that trisomy of a normal gene region results in CMT1A. The smallest duplication does not include the 409 locus used previously to screen for CMT1A duplications. Direct analysis of interphase nuclei from fetuses and at-risk patients by multicolor in situ hybridization to a commonly duplicated CMT1A probe is informative more often than polymorphic PCR analysis, faster than pulsed field gel electrophoresis (PFGE), and faster, more informative, and more reliable than restriction enzyme analysis. CMT1B restriction enzyme analysis of CMT pedigrees without CMT1A is expected to diagnose another 8% of at-risk CMT1 patients (total: 78%).
Use of 3H-cholesteryl linoleyl ether for the quantitation of plasma cholesteryl ester influx into the aortic wall in hypercholesterolemic rabbits. (1982)

In this study use was made of 3H-cholesteryl linoleyl ether CLE), a nondegradable analogue of cholesteryl ester (CE) to measure plasma lipoprotein CE influx into rabbit aorta. Autologous serum labeled with 3H-CLE was injected into seven hypercholesterolemic rabbits, and more than 90% of the label was recovered in the plasma compartment 10 minutes after injection. Between 4 hours and 3 days the label was cleared from the circulation with a t1/2 of about 24 hours. Between 4 and 24 hours the lipoproteins isolated at d less than 1.006, d less than 1.019, and d less than 1.063 approached similar specific activity, assuming that 3H-CLE had mixed with the lipoprotein CE pool. The rabbits were killed 7 to 14 days after injection when plasma radioactivity decreased to less than 0.03% of injected dose/ml. Total recovery of the CLE ranged from 70% to 95% and 48% to 72% were found in the liver. The minimum influx of plasma CE into the aortic intima was determined by dividing the label found in the artery by the mean specific activity of the labeled compound in the plasma. The minimum influx into regions with atheromatous involvement ranged from 0.8 to 3.4 micrograms CE/cm2/hr. The rate of influx was highly correlated with the amount of CE mass in the intima and media indicating that the bulk of aortic CE is derived from plasma lipoprotein CE. The method described might be useful in distinguishing between possible effects of "antiatherogenic" drugs on plasma CE influx into the aortic wall from an effect on intracellular CE hydrolysis and subsequent efflux of free cholesterol from the artery.
Modulation transfer function measurements of HgCdTe long wavelength infrared arrays for the Near-Earth Object Surveyor (2022)

The modulation transfer function (MTF) is a useful measure in image quality analysis and performance budget determination. Sensitive long wavelength infrared (LWIR) detectors for astronomical space telescopes require slight modifications to the existing MTF measurement methods due to the increased prevalence of high dark current pixels. Presented here are the specifics of a modified slanted edge method to determine the MTF in λc > 10 μm HgCdTe detectors to be used with the planned Near-Earth Object Surveyor Mission. The measured MTF at Nyquist using 6 μm light is 0.22 ± 0.02 and is 0.25 ± 0.02 using 10 μm light for both 250 and 350 mV of applied reverse bias. These measurements are from edge spread functions with median signal values around 50% of the well depth, as the MTF is expected to change with signal value due to two brighter-fatter type effects. The expected trends caused by the influences of these two effects and the expected trends with wavelength of absorbed photons are all observed.
YM‐216391, a Novel Cytotoxic Cyclic Peptide from Streptomyces nobilis. Part 1. Fermentation, Isolation and Biological Activities. (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
Progress in Scalable Coating and Roll‐to‐Roll Compatible Printing Processes of Perovskite Solar Cells toward Realization of Commercialization (2018)

Abstract Organic–inorganic halide perovskite solar cells (PeSCs) have attracted worldwide attention due to their excellent photovoltaic properties, such as their proper bandgap, strong light absorption, long exciton diffusion length, and easy device fabrication with solution processes, suggesting a great potential for low‐cost, high‐performance solar cells. After a power conversion efficiency (PCE) of 3.8% achieved in 2009, numerous efforts have been made to create PeSCs with high PCEs over 20% in small‐area cells. The next challenge is transition from the lab‐scale spin coating to a large‐scale coating/printing, which will preferably involve the cost‐competitive roll‐to‐roll manufacturing and vacuum‐free full‐printing process. This review provides a progress report on studies related to the scalable deposition methods for PeSCs, such as slot‐die coating, blade coating, spray coating, and various other methods, and to their processing strategies for morphology control in perovskite film formation and discusses the challenges and potential of commercialization of PeSCs in the future.
A Stripe-to-Droplet Transition Driven by Conformational Transitions in a Binary Lipid−Lipopolymer Mixture at the Air−Water Interface (2011)

We report the observation of an unusual stripe-droplet transition in precompressed Langmuir monolayers consisting of mixtures of poly(ethylene) glycol (PEG) amphiphiles and phospholipids. This highly reproducible and fully reversible transition occurs at approximately zero surface pressure during expansion (or compression) of the monolayer following initial compression into a two-dimensional solid phase. It is characterized by spontaneous emergence of an extended, disordered stripe-like morphology from an optically homogeneous phase during gradual expansion. These stripe patterns appear as a transient feature and continuously progress, involving gradual coarsening and ultimate transformation into a droplet morphology upon further expansion. Furthermore, varying relative concentrations of the two amphiphiles and utilizing amphiphiles with considerably longer ethylene glycol headgroups reveal that this pattern evolution occurs in narrow concentration regimes, values of which depend on ethylene oxide headgroup size. These morphological transitions are reminiscent of those seen during a passage through a critical point by variations in thermodynamic parameters (e.g., temperature or pressure) as well as those involving spinodal decomposition. While the precise mechanism cannot be ascertained using present experiments alone, our observations can be reconciled in terms of modulations in competing interactions prompted by the pancake-mushroom-brush conformational transitions of the ethylene glycol headgroup. This in turn suggests that the conformational degree of freedom represents an independent order parameter, or a switch, which can induce large-scale structural reorganization in amphiphilic monolayers. Because molecular conformational changes are pervasive in biological membranes, we speculate that such conformational transition-induced pattern evolution might provide a physical mechanism by which membrane processes are amplified.
Enhanced CO catalytic oxidation of flower-like Co3O4composed of small nanoparticles (2016)

The enhanced catalytic performance of flower-like Co<sub>3</sub>O<sub>4</sub>composed of nanoparticles originates from the redistribution of surface ions induced by the calcining process.
An acidic or basic amino acid at position 26 of the b subunit of Escherichia coli F1F0-ATPase impairs membrane proton permeability: suppression of the uncF469 nonsense mutation (1984)

The uncF469 allele differed from normal in that a G----A base change occurred at nucleotide 77 of the uncF gene, resulting in a TAG stop codon rather than the tryptophan codon TGG. Two partial revertant strains were isolated which retained the uncF469 allele but formed a partially functional b-subunit, due to suppression of the uncF469 nonsense mutation. From the altered isoelectric points of the b-subunits from these strains, it was concluded that the suppressor gene of partial revertant strain AN1956 inserts an acidic amino acid for the TAG codon, and that the suppressor gene of partial revertant strain AN1958 inserts a basic amino acid. The membranes of both partial revertant strains showed impaired permeability to protons on removal of F1-ATPase. The membranes of both strains, however, were able to carry out oxidative phosphorylation, and the ATPase activities of both were resistant to the inhibitor dicyclohexylcarbodiimide.
Fatigue Properties of Extruded AZ61 and AZ31 Magnesium Alloys (2010)

High and low cycle fatigue tests were conducted for extruded magnesium alloys, AZ31 and AZ61. In the high cycle fatigue properties, AZ61 showed higher fatigue strength than AZ31, while both alloys did not show fatigue limits. In this case, the rotating bending tests revealed higher fatigue strength than uniaxial loading tests. In the low cycle fatigue properties, AZ31 and AZ61 revealed almost equal fatigue strength under constant strain amplitude tests. However, the hysteresis loops were very unique, showing anisotropy between tension and compression sides.
Two New, Metastable Polymorphs of Lithium Pyrophosphate Li4P2O7 (2018)

By quenching a melt of Li 4 P 2 O 7 two new, thermodynamically metastable polymorphs are obtained as biphasic mixtures. The crystal structure of one polymorph was determined from single‐crystal X ‐ray diffraction data {Li 4 P 2 O 7 ‐trig*: colorless, trigonal, P 3 2 12 (no. 153), Z = 3, a = 5.1699(2) Å, c = 18.9722(8) Å, 60 parameters, R 1 = 0.018, wR 2 = 0.051, 1265 unique reflections with F o &gt; 4 σ (F o )}. For the second polymorph a structure model was derived, using direct space methods followed by Rietveld refinement {Li 4 P 2 O 7 ‐pseudomono*: P 1 , a = 7.88468(5) Å, b = 10.30394(6) Å, c = 7.54581(4) Å, α = 89.8142(6)°, β = 115.26(2)°, γ = 90.2015(5)°, R I = 7.62}. 31 P‐MAS‐NMR measurements show δ iso = –2.9 ppm for Li 4 P 2 O 7 ‐pseudomono* and δ iso = –6.6 ppm for the trigonal polymorph. Substitution of about 10 % lithium by copper(I) is possible in the trigonal as well as in the long known triclinic polymorph as is evidenced by the results of SXRD, XRPD, and 31 P‐MAS‐NMR measurements.
Nano-Scale ZnO Buffer Layer for Inkjet-Printed Polymer Solar Cells (2008)

Zinc oxide (ZnO) was used as a buffer layer in the fabrication of polymer solar cells with the configuration of ITO/PEDOT:PSS/P3HT:PCBM/ZnO/Ag, in which the Ag cathode was prepared by inkjet printing using silver ink. Due to the hydrophobic nature of the P3HT:PCBM active layer surface, the hydrophilic silver ink cannot be coated directly on the top of the P3HT:PCBM layer. To overcome this problem, ZnO particles, prepared in a simple solution method by using polyethylene glycol (PEG) surfactant molecules, were used as a buffer layer between the P3HT:PCBM layer and Ag cathode. The present study discusses and compares the performance of the solar cells with and without the ZnO buffer layer.
Author Correction: Development of new method to enrich human iPSC-derived renal progenitors using cell surface markers (2019)

A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
Incidence and Predisposing Factors of Postoperative Infection after Rhinoplasty: A Single Surgeon’s 16-Year Experience with 2630 Cases in an East Asian Population (2022)

Therapeutic, IV.
Biocompatible Calcium Ion-Doped Magnesium Ferrite Nanoparticles as a New Family of Photothermal Therapeutic Materials for Cancer Treatment (2023)

Novel biocompatible and efficient photothermal (PT) therapeutic materials for cancer treatment have recently garnered significant attention, owing to their effective ablation of cancer cells, minimal invasiveness, quick recovery, and minimal damage to healthy cells. In this study, we designed and developed calcium ion-doped magnesium ferrite nanoparticles (Ca<sup>2+</sup>-doped MgFe<sub>2</sub>O<sub>4</sub> NPs) as novel and effective PT therapeutic materials for cancer treatment, owing to their good biocompatibility, biosafety, high near-infrared (NIR) absorption, easy localization, short treatment period, remote controllability, high efficiency, and high specificity. The studied Ca<sup>2+</sup>-doped MgFe<sub>2</sub>O<sub>4</sub> NPs exhibited a uniform spherical morphology with particle sizes of 14.24 ± 1.32 nm and a strong PT conversion efficiency (30.12%), making them promising for cancer photothermal therapy (PTT). In vitro experiments showed that Ca<sup>2+</sup>-doped MgFe<sub>2</sub>O<sub>4</sub> NPs had no significant cytotoxic effects on non-laser-irradiated MDA-MB-231 cells, confirming that Ca<sup>2+</sup>-doped MgFe<sub>2</sub>O<sub>4</sub> NPs exhibited high biocompatibility. More interestingly, Ca<sup>2+</sup>-doped MgFe<sub>2</sub>O<sub>4</sub> NPs exhibited superior cytotoxicity to laser-irradiated MDA-MB-231 cells, inducing significant cell death. Our study proposes novel, safe, high-efficiency, and biocompatible PT therapeutics for treating cancers, opening new vistas for the future development of cancer PTT.
Addressing Ligand-Based Redox in Molybdenum-Dependent Methionine Sulfoxide Reductase (2020)

A combination of pulsed EPR, CW EPR, and X-ray absorption spectroscopies has been employed to probe the geometric and electronic structure of the <i>E. coli</i> periplasmic molybdenum-dependent methionine sulfoxide reductase (MsrP). <sup>17</sup>O and <sup>1</sup>H pulsed EPR spectra show that the <i>as-isolated</i> Mo(V) enzyme form does not possess an exchangeable H<sub>2</sub>O/OH<sup>-</sup> ligand bound to Mo as found in the sulfite oxidizing enzymes of the same family. The nature of the unusual CW EPR spectrum has been re-evaluated in light of new data on the MsrP-N45R variant and related small-molecule analogues of the active site. These data point to a novel "thiol-blocked" [(PDT)Mo<sup>V</sup>O(S<sub>Cys</sub>)(thiolate)]<sup>-</sup> structure, which is supported by new EXAFS data. We discuss these new results in the context of ligand-based and metal-based redox chemistry in the enzymatic oxygen atom transfer reaction.
NETCONF Configuration Protocol (2006)

The Network Configuration Protocol (NETCONF) defined in this document
provides mechanisms to install, manipulate, and delete the
configuration of network devices. It uses an Extensible Markup
Language (XML)-based data encoding for the configuration data as well
as the protocol messages. The NETCONF protocol operations are realized
on top of a simple Remote Procedure Call (RPC) layer. [STANDARDS-
TRACK]
Powder Metallurgy Methods and Applications (2015)

Abstract This article reviews various segments of the powder metallurgy (PM) process from powder production and powder processing through the characterization of the materials and their properties. It covers the processing methods for consolidating metal powders including options for processing to full density. The article outlines the freeform fabrication process, also known as additive manufacturing and describes finishing operations of PM parts. It concludes with information on the applications of PM parts.