gebhart/patrepeval huggingface dataset:
Health information technology: A key ingredient of the patient experience (2015)

In this exploration to understand the linkages of health information technology (HIT) and patient experience, a comprehensive literature search was conducted using the key words, “information technology, HIT, patient experience, patient satisfaction, and technology”, on the MEDLINE, PubMed, and EMBASE databases resulting in over 1,000 citations. Eventually, 35 of the most relevant articles were reviewed and 11 identified as key references to include in beginning to explore the question, as the transformation of healthcare continues, how can technology enable a positive return on investment to a patients’ perception of their care in an organization and how can technology impact the patient experience? The results reveal there is in fact more questions than answers that exits and therefore further opportunities for exploration and research are encouraged. That noted, the literature and examples emerging in practices across healthcare are showing that technology and the patient experience are moving closer to one another as each day passes. HIT is truly evolving as a key ingredient in the patient experience conversation.
Experimental Investigations of Tapered Fuel Regression Rate of Hybrid Rocket Motor (2010)

The purpose of this research is to investigate a way of improving the non uniformity of the local regression rate in a cylindrical or multiport grain which is an inherent disadvantage of hybrid rocket combustion. A lab scale Hybrid Rocket Motors (HRM) using tapered solid grain (convergent or divergent) having different taper angles is opted for our study. The non uniform local regression rate can not only cause the slivers of solid fuel, but also cause early port merging in the pre and aft section of the multiport grain during combustion. Experiments are conducted to confirm whether taper angles can relax the non uniformity of the local regression rate or influence the performance of lab scale HRMs. In this study, the steeping method is used to measure the accurate local regression rate of tapered grain with taper angles of 1 and 2 degrees. Combustion characteristics such as the overall regression rate and the characteristic velocities are compared with those of cylindrical grain to see taper angles effects on the performance. The possibility of improving the overall regression rate and the non uniformity of local regression rate is discussed.
Treatment Guidelines for Acute Manic and Mixed Episodes of Bipolar Disorder (2009)

Bipolar disorder is a lifelong condition, and pharmacotherapy is essential to its long-term management. Once a comprehensive diagnostic assessment for acute or mixed mania has been completed, it is important to look at an evidence-based data set to guide treatment selection for mood stabilization. For most patients, lifetime adherence to pharmacotherapy is necessary for maximal mood stability. Pharmacotherapy is the primary treatment for bipolar disorder, as it has been found to be efficacious in treating acute episodes and preventing future episodes of bipolar I disorder. Combination therapy, including at least one mood stabilizer, may be necessary to treat acute depression and mania and to further prevent both depressive and manic recurrences. The goal is to minimize frequency, duration, and severity of depressive and manic symptoms with a treatment regimen, ideally a combination of pharmacotherapy and psychotherapy, that is positioned to maximize treatment adherence and minimize side effects. This discussion reviews some treatment guidelines for acute manic and mixed episodes associated with bipolar I disorder. Through the context of a case study, this discussion will attempt to provide an understanding and appreciation of Food and Drug Administration-approved and non-FDA-approved treatments for acute mania. In addition, the impact of alcohol as an example of drugs of abuse and its impact on the presentation of acute mania will be discussed.
Recommendation via Entering a Human Conversation (2023)

Abstract We propose a novel way of the conversational recommendation where instead of asking user questions to acquire her preferences, the recommender tracks her conversations with other people, including customer support agents (CSA) and joins the conversation only when there is something important to recommend and the time is correct to do so. Building a recommender that joins a human conversation (CRS), we propose information extraction, discourse and argumentation analyses, as well as dialogue management techniques to compute a recommendation for a product and service that is badly needed by the customer, as inferred from the conversation. A special case of such conversations is considered where the customer raises his problem with a CSA in an attempt to resolve at, along with receiving a recommendation for a product with features addressing this problem. Performance of CRS is evaluated in a number of human-human and human-chatbot dialogues and demonstrates that CRS is efficient and less intrusive way to provide high relevance and persuasive recommendations.
Development of Whispering Gallery Mode Polymeric Micro-optical Electric Field Sensors (2013)

Optical modes of dielectric micro-cavities have received significant attention in recent years for their potential in a broad range of applications. The optical modes are frequently referred to as "whispering gallery modes" (WGM) or "morphology dependent resonances" (MDR) and exhibit high optical quality factors. Some proposed applications of micro-cavity optical resonators are in spectroscopy1, micro-cavity laser technology2, optical communications3-6 as well as sensor technology. The WGM-based sensor applications include those in biology7, trace gas detection8, and impurity detection in liquids9. Mechanical sensors based on microsphere resonators have also been proposed, including those for force10,11, pressure12, acceleration13 and wall shear stress14. In the present, we demonstrate a WGM-based electric field sensor, which builds on our previous studies15,16. A candidate application of this sensor is in the detection of neuronal action potential. The electric field sensor is based on polymeric multi-layered dielectric microspheres. The external electric field induces surface and body forces on the spheres (electrostriction effect) leading to elastic deformation. This change in the morphology of the spheres, leads to shifts in the WGM. The electric field-induced WGM shifts are interrogated by exciting the optical modes of the spheres by laser light. Light from a distributed feedback (DFB) laser (nominal wavelength of ~ 1.3 μm) is side-coupled into the microspheres using a tapered section of a single mode optical fiber. The base material of the spheres is polydimethylsiloxane (PDMS). Three microsphere geometries are used: (1) PDMS sphere with a 60:1 volumetric ratio of base-to-curing agent mixture, (2) multi layer sphere with 60:1 PDMS core, in order to increase the dielectric constant of the sphere, a middle layer of 60:1 PDMS that is mixed with varying amounts (2% to 10% by volume) of barium titanate and an outer layer of 60:1 PDMS and (3) solid silica sphere coated with a thin layer of uncured PDMS base. In each type of sensor, laser light from the tapered fiber is coupled into the outermost layer that provides high optical quality factor WGM (Q ~ 106). The microspheres are poled for several hours at electric fields of ~ 1 MV/m to increase their sensitivity to electric field.
Time Efficient Integrated Electro-Thermal Model for Bidirectional Synchronous DC-DC Converter in Hybrid Electric Vehicles (2018)

This paper introduces a simple and fast method to calculate the junction temperature of power electronic devices in a 3-phase DC-DC converter by representing converter dynamics during a simulated drive cycle. Simulating a DC-DC converter as a switching model during a drive cycle, which can have durations of 1000 to 2000 seconds or more, requires long simulation times and/or high-processing units like cluster computers. Thus, this paper presents a state-space averaged model to describe the 3- phase interleaved converter dynamics in buck and boost modes. Converter dynamics of the averaged model are compared to those of the switching model at different operating conditions to validate the model. The full Simulink model includes a battery model, the buck-boost average model, a buck-boost temperature- dependent power loss model, and a thermal model. The power loss calculated by the proposed method is compared to that of the switching Simulink/PLECS model, and the error is found to be less than 4% over a variety of operating points.
Avian paramyoxvirus-8 immunization reduces viral shedding after homologous APMV-8 challenge but fails to protect against Newcastle disease (2014)

Immune responses mounted during asymptomatic APMV-8 infection limit secondary infection against homologues reinfection and facilitates a delay in the onset of disease in a subtype independent manner but is unable to protect against Newcastle disease, a heterologous APMV-subtype.
Ultralow Energy van der Waals InSe PN junction heterostructure photodetector for NIR applications (2022)

We show a self-driven indium selenide (InSe) p-n heterojunction photodetector with a threefold increase in responsivity at 980 nm over a photoconductor detector based on p- or n-doped regions.
Model Predictive Direct Power Control of PWM Rectifiers Under Unbalanced Network Conditions (2015)

Model predictive direct power control (MPDPC) has been proposed as an effective alternative to conventional direct power control for pulsewidth-modulation (PWM) rectifiers. However, the sampling frequency of MPDPC still has to be high to achieve satisfactory performance. Furthermore, the grid currents of MPDPC would become highly distorted under unbalanced network conditions. To cope with the problems above, this paper proposes an improved MPDPC for PWM rectifiers, which is able to operate under both balanced and unbalanced grid voltages. By using a new definition of instantaneous reactive power in the predefined cost function, the proposed MPDPC can obtain sinusoidal grid currents and eliminate twice grid-frequency oscillation in both active power and the new reactive power. Neither complicated positive/negative-sequence extraction of grid voltage/current nor power compensation is required. Depending on the desired performance, two variants of the improved MPDPC are proposed and comparatively studied. At the same sampling frequency, the first approach achieves relatively low switching frequency, whereas the second approach obtains lower power ripples. Both simulation and experimental results are presented to confirm the effectiveness of the proposed methods.
Regulating Cytokine Function Enhances Safety and Activity of Genetic Cancer Therapies (2013)

Genetic therapies, including transfected immune cells and viral vectors, continue to show clinical responses as systemically deliverable and targeted therapeutics, with the first such approaches having been approved for cancer treatment. The majority of these employ cytokine transgenes. However, expression of cytokines early after systemic delivery can result in increased toxicity and nonspecific induction of the immune response. In addition, premature immune-mediated clearance of the therapy may result, especially for viral-based approaches. Here, it was initially verified that cytokine (interleukin (IL)2) or chemokine (CCL5) expression from a systemically delivered oncolytic virus resulted in reduced oncolytic activity and suboptimal immune activation, while IL2 also resulted in increased toxicity. However, all these limitations could be overcome through incorporation of exogenous regulation of cytokine or chemokine transgene function through fusion of a small and externally controllable destabilizing domain to the protein of interest. Regulation allowed an initial phase without cytokine function, permitting enhanced delivery and oncolytic activity before activation of cytokine function and a subsequent phase of enhanced and tumor-targeted immunotherapeutic activity. As a result of this exogenous regulation of cytokine function, both oncolytic and immune-mediated mechanisms of action were optimized, greatly enhancing therapeutic activity, while toxicity was significantly reduced.
Physical and Social Human-robot Interaction (2020)

This talk covers two main research directions based on the iCub humanoid robot. The iCub is a humanoid robot designed to support research in embodied AI. At 104 cm tall, the iCub has the size of a five-year-old child. It can crawl on all fours, walk, and sit up to manipulate objects. Its hands have been designed to support sophisticate manipulation skills. The iCub is distributed as Open Source following the GPL license and can now count on a worldwide community of enthusiastic developers. There are more than 40 robots available in laboratories across the globe. The iCub sensory system allows seeing, hearing and feeling physical contacts. It is one of the few platforms in the world with a sensitive full-body skin. The iCub is being used at the Italian Institute of Technology as a model platform to develop the technology of future interactive service robots. In particular, I will describe our work in the field of physical and social interaction. For example, through extensive use of machine learning, we developed algorithms to interpret and use external contact information in a variety of tasks as well as contactless cues - vision, sound - to ease interaction between the user and the robot.
[Diagnosis of Alzheimer's disease using brain SPECT with three-dimensional stereotactic surface projections]. (2001)

We compared the diagnostic usefulness of three-dimensional stereotactic surface projection (3D-SSP) with that of standard transaxial images in brain SPECT in patients with Alzheimer's disease (AD). The subjects consisted of 69 patients with AD and 60 patients with non-AD, including vascular dementia, Parkinson's disease with dementia, frontotemporal dementia, other dementing diseases and neuropsychiatric diseases. Standard transaxial section and 3D-SSP SPECT images with N-isopropyl-p-[123I] iodoamphetamine were blindly interpreted by three examiners and were classified into the following three patterns: typical AD, atypical AD, and not indicative AD patterns. The 3D-SSP images demonstrated reductions of cerebral blood flow in the parieto-temporal association cortex and posterior cingulate gyrus more clearly and easily than the standard transaxial images. The diagnostic sensitivity and specificity were 93% and 85% with 3D-SSP and 83% and 82% with standard transaxial section respectively. 3D-SSP was especially useful for early or atypical AD which showed no characteristic perfusion abnormalities on standard transaxial images. These results suggest that SPECT with 3D-SSP provides an sensitive as well as accurate tool for the diagnosis of AD.
Micromethods for the Characterization of Lipid A-Core and O-Antigen Lipopolysaccharide (2006)

Methods for rapid and simple analysis of lipopolysaccharide (LPS) from bacterial whole-cell lysates or membrane preparations have contributed to advancing our knowledge of the genetics of the LPS biogenesis. LPS, a major constituent of the outer membranes in Gram-negative bacteria, has a complex mechanism of synthesis and assembly that requires the coordinated participation of many genes and gene products. This chapter describes a collection of methods routinely used in our laboratory for the characterization of LPS in Escherichia coli and other bacteria.
Paper Plane: Towards Disposable Low-Cost Folded Cellulose-Substrate UAVs (2012)

Disposable folded cellulose-substrate micro-Unmanned Aerial Vehicles (UAVs) - paper planes - have the surprising potential to be effective platforms for deploying remote sensors at low-cost. With inexpensive inertial sensors and circuits printed on inexpensive structural material, the cost of a mini-scale aircraft can be reduced to the point that discarding the aircraft post-mission is economical. When launched from high-altitude balloons, paper UAVs capable of navigating jet-stream winds could be guided to land anywhere on Earth with no additional power input. This paper discusses paper as a multi-functional electronic-aeromechanical material for use in disposable micro UAVs. A proof of concept paper aircraft with inertial sensors and elevons, is presented and it is show that glide performance of the aircraft is not compromised by added mass.
High Range Resolution (HRR) profiling within low elevation search mode (2008)

In this paper, we describe the high range resolution (HRR) profiling technique for generating the target range profile while the radar is in the low elevation search mode. The major advantage of this concept is reuse of the moving target detection (MTD) radar data for formulating the target range profile to provide the early target classification, discrimination, and identification (CDI) decision for all targets. This technique is developed for air missile defense pulse Doppler radar in which transmitting frequency is changing within the transmit pulse width. Here, we also discuss the effects of phase variation introduced by radial target motion and address how to compensate those effects.
Applying Logic Programming to the Specification of Complex Applications. (1997)

In this paper we show how multi-theory logic programming techniques can be profitably applied to the realization of multi-agent systems which solve complex problems. Our goal is to use logic programming as a tool to give an executable specification of a multi-agent system, obtained from a high-level informal description of the interactions among the different system components. We have implemented a planner for goods transportation as a demonstration of such an approach. KEYWORDS Multi--agent systems, logical theories, meta--programming, specification. INTRODUCTION The agent paradigm has become, in the last few years, an important developing methodology for complex applications, involving problems like coordination, communication, sharing and integration of knowledge. The advantage of this technology is the ability of modelling heterogeneous programming environments, and its drawback is the lack of standard methods to build the desired system, defining and putting together the vario...
Temperature Compensation of a MEMS Resonator Using Quality Factor as a Thermometer (2006)

Silicon MEMS resonators have great potential for on-chip high frequency signal applications. This paper compares methods of sensing the temperature of an encapsulated silicon MEMS resonator and using this temperature measurement to stabilize the temperature, and hence the resonant frequency, of the resonator. The use of external Pt RTDs, integrated Si thermistors, and the use the Quality factor (Q) of the resonator are explored. Use of the Q as a temperature sensor is explored in detail as it is a nearly ideal temperature sensing method. Characterisations of the temperature sensors and preliminary temperature control results are presented.
STUDY ON CO_2 CURING KINETICS OF CONCRETE (2010)

CO2 curing of concrete is based on the chemical reactions between CO2 and cement clinker minerals,resulting in the hardening and strength development of concrete.Temperature profile,strength development and degree of CO2 curing were measured.A kinetic model for concrete curing with CO2 was also proposed.It was indicated that the model can describe the CO2 curing kinetics.
A comprehensive proteome map of the lipid‐requiring nosocomial pathogen Corynebacterium jeikeium K411 (2007)

Corynebacterium jeikeium is a lipid-requiring pathogen that is considered as part of the normal microflora of the human skin and associated with severe nosocomial infections. Systematic reference maps of the cytoplasmic, cell surface-associated, and extracellular proteome fractions of the clinical isolate C. jeikeium K411 were examined by 2-DE coupled with MALDI-TOF MS. A sum total of 555 protein spots were identified by PMF, corresponding to 358 different proteins that were classified into functional categories and integrated into metabolic pathways. The majority of the proteins were linked to housekeeping functions in energy production and translation and to physiological processes in amino acid, carbohydrate, nucleotide, and lipid metabolism. A complete enzymatic machinery necessary to utilize exogenous fatty acids by beta-oxidation was detected in the cytoplasmic proteome fraction. In addition, several predicted virulence factors of C. jeikeium K411 were identified in the cell surface-associated and extracellular subproteome, including the cell surface proteins SurA and SurB, the surface-anchored pilus subunits SapA and SapB, the surface-anchored collagen adhesin CbpA, the cholesterol esterase Che, and the acid phosphatase AcpA.
8Gbps high-speed I/O transmitter with scalable speed, swing and equalization levels (2010)

A novel transmitter that supports wide range data rates up to 8Gb/ps is introduced in this paper. A reconfigurable bitslice CML based driver offers the programmable swing and de-emphasis levels that are suitable for Gbps series data links such as Gen1 and Gen2 PCI-Express and SATA circuits. The chip is fabricated in a 45nm CMOS technology that occupies an area of 150um×50um with measured power dissipation of 38 mW at 5Gbps data rate.
B cell clonal elimination induced by membrane-bound self-antigen may require repeated antigen encounter or cell competition (2000)

Transgenic mouse experiments indicate that autoreactive B cells are eliminated upon encounter with membrane self-antigen. In this study we tested how B cell tolerance to MHC class I antigens is affected by altering the frequency of antigen-carrying cells in mixed bone marrow (BM) chimeras. When antigen-bearing cells are present at low frequency, the reactive B cells and their antigens may coexist in the peripheral lymphoid organs, but under these conditions the B cells are functionally anergic and have a shortened lifespan. Such putative anergic cells are strongly deleted in the presence of additional, non-antigen-bearing, non-transgenic B cells. Since the antigen concentration on the surface of each antigen-bearing cell should be high, these results suggest that for efficient deletion of autoreactive B cells multiple antigen encounters may be required, particularly when cellular competition is weak. These results have implications for the therapeutic use of BM chimerism to induce B cell tolerance to grafts.
Use of ab Initio Calculations toward the Rational Design of Room Temperature Ionic Liquids (2003)

Ionic liquids are gaining substantial interest as alternative reaction media. Despite the overwhelming amount of evidence suggesting a relationship between their structure and melting point, there still remains the problem of selectively choosing a particular ionic pair that will produce a liquid at room temperature. Ionic liquids based on 1-alkyl-3-methylimidazolium halides have been investigated using ab initio calculations utilizing Gaussian 98 and the 6-31G* and 6-31+G* basis sets. The calculated interaction energy was found to increase in magnitude with decreasing alkyl chain length at the Hartree−Fock level, although no trend was found to exist with increasing anionic radius. Correlations between melting point and interaction energy were investigated. Linear trends were found to exist in the 1-n-butyl-3-methylimidazolium (Bmim) halide series as well as the 1-alkyl-3-methylimidazolium iodide series.