gebhart/patrepeval huggingface dataset:
Feasibility of Renewable Energy Technology at the Afghanistan National Security University: A Site-Specific Study Focused on Potential Renewable Energy Technologies in Northwest Kabul, Afghanistan (2011)

Abstract : This work conducted a site-specific feasibility study to assess the potential use of renewable energy to reduce or replace planned fossil fueled generators at the Afghanistan National Security University (ANSU) and its supporting facilities located in Qargha, Kabul, Afghanistan. On completion of all phases of construction, ANSU will consume approximately $45M of diesel fuel annually for power production. The Afghanistan Engineer District-North commissioned the US Army Corps of Engineers, Engineering Research and Development Center, Construction Engineering Research Laboratory (ERDC-CERL) to investigate renewable energy solutions to reduce that annual fuel cost. The team investigated the following technologies: solar photovoltaic (ground-mounted and building-integrated), solar domestic hot water (DHW), wind, geothermal, geo-thermal (ground-source) heat pumps, waste-to energy (including biomass), solar air collector, solar air ventilation, fuel cells, and hydroelectric power. Qualitative facility demand and energy reduction measures were also included. These energy conservation measures can be used as part of the planning and design phases of construction. On review of all potential options, it was determined that seven renewable energy systems were viable, and eight renewable energy technologies were not viable.
A New Systematic Construction of Zero Correlation Zone Sequences Based on Interleaved Perfect Sequences (2008)

In the literature, many constructions of zero correlation zone (ZCZ) sequences have been reported. While most of them are suboptimal with respect to the known upper bound, some constructed by Matsufuji et al. and Torii et al. respectively, are almost optimal (or even optimal). In this paper, we propose a systematic construction of almost optimal ZCZ sequence sets which generalizes the aforementioned constructions so that more flexible relationships between the set size and the sequence length are allowed. In particular, the obtained almost optimal ZCZ sequence sets of size m and length mn are new for 1 < gcd(m, n) < min(m, n). In addition, their alphabets can be binary or nonbinary since our construction is only based on interleaving perfect sequences according to a certain orthogonal matrix.
Signal processing in SETI (1985)

The Search for Extraterrestrial Intelligence (SETI), now being planned at NASA, will require a prodigious amount of highly concurrent signal processing to be done in real time by special-purpose hardware.
Letter to the Editor (2018)

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RUG-II Impacts on Long-Term Care Facilities in New York (1994)

This article observes changes during the first 5 years of Resource Utilization Group, Version II (RUG-II) system utilization by the New York State Department of Health (NYDOH) for Medicaid program reimbursement. Findings include a dramatic increase in the number of residents scoring in the highest intensity resident-care categories, a substantial increase in staffing and expenditures for rehabilitation therapies, and a possible negative impact on the financial performance of New York long-term care (LTC) facilities. RUG-II appears to have been successful in improving access to nursing homes for individuals with heavy-care needs and in encouraging the appropriate utilization of institutionalized skilled nursing care.
Wave-Drag Characteristics of an Over-the-Wing Nacelle Business-Jet Configuration (2003)

This paper presents the wave-drag characteristics of an over-the-wing nacelle cone guration. The e ow over the wing is accelerated such that the aerodynamic interference between the nacelle and the wing is critical in the transonic e ight regime.In general, locating nacellesoverthewing causesanunfavorableaerodynamicinterference and inducesa strongshock wave,which resultsina lowerdrag-divergenceMach number. Ifthenacelleislocated at the optimum position relative to the wing, however, the shock wave can be minimized, and drag divergence occurs at a Mach number higher than that for the clean-wing cone guration. Theoretical analyses and experimental measurements demonstrate that a wave-drag reduction can be achieved by locating the nacelle front face near the shock-wave position on the wing.
Sphingosine 1-Phosphate, Present in Serum-derived Lipoproteins, Activates Matriptase (2002)

We describe here a novel biological function of sphingosine 1-phosphate (S1P): the activation of a serine protease, matriptase. Matriptase is a type II integral membrane serine protease, expressed on the surface of a variety of epithelial cells; it may play an important role in tissue remodeling. We have previously reported that the activation of matriptase is regulated by serum. We have now identified the bioactive component from serum. First, the activity was observed to co-purify with lipoproteins by conventional liquid chromatography and immunoaffinity chromatography. The ability of lipoproteins to induce the activation of matriptase was further confirmed with commercial preparations of low density lipoprotein (LDL) and very low density lipoprotein (VLDL). Next, we observed that the bioactive component of LDL is associated with the phospholipid components of LDL. Fractionation of lipid components of LDL by thin layer chromatography (TLC) revealed that the bioactive component of LDL comigrates with S1P. Nanomolar concentrations of commercially obtained S1P were then observed to induce the rapid activation of matriptase on the surfaces of nontransformed human mammary epithelial cells. Other structurally related sphingolipids, including dihydro-S1P, ceramide 1-phosphates, and sphingosine phosphocholine as well as lysophosphatidic acid, can also induce the activation of matriptase, but at significantly higher concentrations than S1P. Furthermore, S1P-dependent matriptase activation is dependent on Ca(2+) but not via G(i) protein-coupled receptors. Our results demonstrate that bioactive phospholipids can function as nonprotein activators of a cell surface protease, suggesting a possible mechanistic link between S1P and normal and possibly pathologic tissue remodeling.
Evaluation of the neuro‐protective effect ofArtemisia judaicaextract in a murine diabetic model (2020)

Chronic hyperglycemia is associated with several negative outcomes including neuronal injury. Medicinal plants supplementation has been widely applied to treat or decrease diabetic complications. Here, the possible neuroprotective effect of Artemisia judaica extract (AjE. 300 mg kg<sup>-1</sup> day<sup>-1</sup> ) against neuronal deficits in diabetes model induced by high-fat diet (HFD) administration and streptozotocin (STZ, 30 mg/Kg) injection in rats was investigated. Diabetic rats showed a disturbance in the neuronal redox homeostasis as confirmed by the elevated lipoperoxidation and nitric oxide formation along with the decreased antioxidant molecules. In addition, a state of neuroinflammation and apoptosis were recorded in the brain tissue in diabetic rats. Furthermore, HFD/STZ provoked neurochemical alterations. However, AjE administration was found to abrogate significantly the neuronal impairments associated with diabetes. This neuroprotective effect comes from its strong antioxidant, anti-inflammatory, antiapoptotic, and neuromodulatory activity; suggesting that AjE may be applied to alleviate neurological impairments in diabetic patients. PRACTICAL APPLICATIONS: Diabetes mellitus (DM) is a metabolic disorder characterized by high blood glucose level comes from the dysregulation of insulin production and/or its action. The persisted hyperglycemia is correlated with the progression of several physical complications including renal, hepatic, vascular, retinal, and neuronal dysfunction. Artemisia is used in the nutritional and medicinal proposes due to the enriched bioactive molecules such as essential oil, flavonoids, phenolics, sesquiterpenoids, triterpenoids, and artemisinin. And we found that Artemisia judaica extract (AjE) administration was able to abrogate significantly the neuronal impairments associated with diabetes. This neuroprotective effect comes from its strong antioxidant, anti-inflammatory, anti-apoptotic and neuromodulatory activity; suggesting that AjE may be applied to alleviate neurological impairments in diabetic patients.
Carbohydrate deficient glycoprotein syndrome type Ia. (2004)

Carbohydrate deficient glycoprotein syndromes (CDG) are inherited multisystem disorders characterized by the abnormal glycosylation of a number of serum glycoproteins. CDG-Ia results from deficiency of phosphomannomutase that catalyzes the conversion of mannose-6-phosphate to mannose-1-phosphate in the cytosol. We report a case of CDG-Ia in an 11-month-old girl with developmental delay, failure to thrive, inverted nipples and abnormal fat pads. The abnormal pattern of transferrin glycosylation and phosphomannomutase activity assay confirmed the diagnosis of CDG type Ia. Unfortunately, an efficient treatment is still not available for CDG type Ia patients. This is the first report of a Taiwanese patient with this syndrome.
Functional Model-Based Design Methodology for Automotive Cyber-Physical Systems (2015)

The high complexity of cross-domain engineering in combination with the pressure for system innovation, higher quality, time to market, and budget constraints makes it imperative for automotive companies to use integrated engineering methods and tools. Computer engineering tools are mainly focused on a particular domain, and therefore, it is difficult to integrate different tools for system-level analysis. In this paper, a novel multidisciplinary systems engineering methodology and associated design automation algorithms for the complex automotive cyber-physical systems are presented. Rather than starting from the domain-specific architecture/simulation models where most resources are spent, we preemptively target the early design stage at the functional level that determines 75% of an automobile's cost. In our methodology, the marriage of systems engineering principles with high-level synthesis techniques from design automation area results in a functional modeling compiler capable of generating high-fidelity simulation models for the design space exploration and validation of multiple cyber-physical automotive architectures. Using real-world automotive use cases, we demonstrate how functional models capturing integrated cyber-physical aspects are synthesized into high-fidelity multidomain simulation models.
An Artificial Nose Based on Microcantilever Array Sensors (2007)

We used microfabricated cantilever array sensors for an artificial nose setup. Each cantilever is coated on its top surface with a polymer layer. Volatile gaseous analytes are detected by tracking the diffusion process of the molecules into the polymer layers, resulting in swelling of the polymer layers and therewith bending of the cantilevers. From the bending pattern of all cantilevers in the array, a characteristic 'fingerprint' of the analyte is obtained, which is evaluated using principal component analysis. In a flow of dry nitrogen gas, the bending of the cantilevers is reverted to its initial state before exposure to the analyte, which allows reversible and reproducible operation of the sensor. We show examples of detection of solvents, perfume essences and beverage flavors. In a medical application, the setup provides indication of presence of diseases in patient's breath samples.
Protein metabolism during weight reduction with very-low-energy diets: evaluation of the independent effects of protein and carbohydrate on protein sparing (1995)

The aim of this study was to assess the independent effects of carbohydrate and protein intakes in protein sparing during weight reduction. Forty-eight obese women were randomly assigned to consume isoenergetic (2500 kJ/d) liquid diets that provided the following amounts (g/d) of protein and carbohydrate, respectively, for 28 d: 50 and 10, 50 and 76, 70 and 10, and 70 and 86. The effects of carbohydrate and protein were analyzed by repeated-measures analysis of variance (ANOVA). Carbohydrate significantly affected daily urinary ammonia and total nitrogen excretion, stool nitrogen, and nitrogen balance. Protein, independently of carbohydrate, significantly affected daily urinary ammonia, urea, and total nitrogen excretion but had no effect on nitrogen balance. Cumulative nitrogen losses (mmol/28 d) were lower in the high-carbohydrate groups than in the low-carbohydrate groups (1869 +/- 392 and 3611 +/- 328, P = 0.003) but were similar in the groups receiving 50 and 70 g protein/d (3171 +/- 327 and 2326 +/- 430, respectively, P = NS). These results indicate that carbohydrate and protein have independent but additive protein-sparing effects during weight reduction.
SEMI-IMPLICIT ALGORITHM OF PARTICLE METHOD ACCELERATED BY GPU (2010)

粒子法は複雑な自由表面の変化の追跡に適していることから，水工学分野でも有用性が示され，海岸工学においては数値波動水槽への応用も進められている．しかし計算負荷が高いため，ハードウェアへの相応の投資が必要となり，これが一般利用の障害となっている．ところで，画像処理目的に開発されてきたGPUを，一般的な学術演算の高速化に利用する取り組みが最近活発となっている．本研究では，MPS法を高速化する手段のひとつとして，CUDAによるGPU併用コードを開発した．高速化を達成するための留意点を整理し，MPS法計算コード固有の特性に適合するように移植を行った．メモリ配置の工夫に加えて，計算のコアとなる近傍粒子探索や圧力のPoisson方程式の収束計算については，GPU計算を効率化するため，特に綿密に検討した．
Proton probing of laser-driven EM pulses travelling in helical coils (2017)

The ultrafast charge dynamics following the interaction of an ultra-intense laser pulse with a foil target leads to the launch of an ultra-short, intense electromagnetic (EM) pulse along a wire connected to the target. Due to the strong electric field (of the order of $\text{GV m}^{-1}$ ) associated to such laser-driven EM pulses, these can be exploited in a travelling-wave helical geometry for controlling and optimizing the parameters of laser accelerated proton beams. The propagation of the EM pulse along a helical path was studied by employing a proton probing technique. The pulse-carrying coil was probed along two orthogonal directions, transverse and parallel to the coil axis. The temporal profile of the pulse obtained from the transverse probing of the coil is in agreement with the previous measurements obtained in a planar geometry. The data obtained from the longitudinal probing of the coil shows a clear evidence of an energy dependent reduction of the proton beam divergence, which underpins the mechanism behind selective guiding of laser-driven ions by the helical coil targets.
Genistein Represses Telomerase Activity via Both Transcriptional and Posttranslational Mechanisms in Human Prostate Cancer Cells (2006)

Genistein, the most abundant isoflavone present in soybean has antiproliferative effects on a variety of cancer cells, including prostate cancer. However, the molecular mechanism of antiproliferative effects of genistein is not entirely understood. Because the activation of telomerase is crucial for cells to gain immortality and proliferation ability, we examined the role of genistein in the regulation of telomerase activity in prostate cancer cells. Here, we show that genistein-induced inhibition in cell proliferation is associated with a reduction in telomerase activity. Using reverse transcriptase-PCR and hTERT promoter activity assays, we showed that genistein decreased hTERT expression and transcriptional activity dose-dependently. Using various deleted hTERT promoter constructs, we defined that the hTERT core promoter is enough to observe the genistein-induced repression of hTERT transcriptional activity. Because c-Myc is involved in transcriptional regulation of hTERT, c-Myc expression was examined. A dose-dependent decrease in c-Myc message and proteins was observed with genistein treatment. These results indicate that genistein represses hTERT transcriptional activity via the down-regulation of c-Myc expression. However, genistein-induced repression of hTERT transcriptional activity was not blocked by the mutation of c-Myc at the hTERT promoter, suggesting that additional factors are involved in genistein-dependent repression of telomerase activity. Interestingly, we observed that genistein down-regulates the activation of Akt thereby phosphorylation of hTERT and inhibits its translocation to the nucleus. These results show for the first time that genistein represses telomerase activity in prostate cancer cells not only by repressing hTERT transcriptional activity via c-Myc but also by posttranslational modification of hTERT via Akt.
Absence of Lateral Phase Segregation in Fatty Acid-Based Catanionic Mixtures (2010)

Mixtures of ionic surfactants of opposite charge ("catanionic" mixtures) show strongly nonideal behaviors, for example, in terms of evolution of surface tension, critical micelle concentration, or morphology with respect to composition in each surfactant. In several catanionic systems, it has been proposed that the interaction between both surfactants is so strong that lateral phase segregation occurs within bilayers, with crystallites of preferential composition demixing from the excess of the other surfactant. Here, we investigate the temperature-composition phase diagram of the myristic acid/cetyltrimethylammonium mixtures. Combining microcalorimetry, X-ray diffusion, and solid-state deuterium NMR, we demonstrate that no separation is observed in the gel (L(beta)) state. The catanionic mixtures therefore behave like two-dimensional solid solutions with a negative azeotrope: the existence of a composition at which a maximum in melting temperature is observed does not imply the existence of a preferential crystal of this composition, but results from the preferential attraction between unlike amphiphilic molecules. Additionally, this study reveals the presence of a so-called intermediate phase, that is, a phase that shows dynamic properties intermediate between that of the L(beta) and the L(alpha) phases.
Harmony: a desktop grid for delivering enterprise computations (2004)

We describe Harmony-a grid infrastructure built using personal computer resources. Harmony addresses the key concerns of end users for responsiveness, privacy and protection by isolating the grid computation in a virtual machine on the PC. Harmony also addresses the key concerns of enterprise IT by automating the configuration and deployment of grid services and by automating the workload management so as to meet quality of service goals. Harmony's layered resource management architecture diverts grid workload to currently under utilized desktop resources. Harmony is designed to handle transactional workload-a key characteristic of commercial applications. Our implementation is Web services-based, so the programming model of Harmony is compatible with and familiar to enterprise developers. We believe that Harmony demonstrates practical exploitation of a hitherto underutilized resource of considerable capability, with the potential to complement, or even in some cases replace, dedicated server-based resources.
Cold Spark Discharge Plasma Treatment of Inflammatory Bowel Disease in an Animal Model of Ulcerative Colitis (2010)

Cold plasma discharges have been shown to have medically-relevant therapeutic effects when applied to living tissues, including blood coagulation and wound healing; thus, plasma treatment of infl amed tissues in ulcerative colitis disease may be an effective approach to reduce adverse consequences if not cure the disease. Here we discuss results of the fi rst experimental study of cold plasma treatment of ulcerative colitis in a mouse model. As a plasma source, a cold spark discharge has been used. The results show that plasma treatment of experimental model of ulcerative colitis in mice has some benefi cial effects by suppressing the progression of the disease while no damage to colon tissues is observed; and these effects are comparable to standard therapy.
Kapitel 9. Adoptionsrecht (Rabe) (2020)

Das Studienbuch wendet sich vor allem an Studierende und Praktiker der Sozialarbeit/Sozialpädagogik. Es vermittelt fundierte Kenntnisse wesentlicher Gebiete des Jugend- und Familienrechts und deckt die für die Ausbildung und Praxis wichtigsten Bereiche ab. Es ist aber auch als Hilfe für diejenigen gedacht, die sich sonst mit dem Jugend- und Familienrecht befassen.
Extraspinal Tendon and Ligament Calcification Associated with Long-Term Therapy with Etretinate (1986)

Isotretinoin, a synthetic retinoid that has been prescribed for over 500,000 patients with cystic acne, has been associated with both spinal hyperostosis and a disorder similar to diffuse idiopathic skeletal hyperostosis. We describe a syndrome of tendon and ligament calcification, primarily in extraspinal locations, that we have observed after long-term therapy for psoriasis and disorders of keratinization with etretinate, another synthetic retinoid. Of 38 patients who had received etretinate (average dose, 0.8 mg per kilogram of body weight per day; average duration, 60 months), 32 (84 percent) had radiographic evidence of extraspinal tendon and ligament calcification. The most common sites of involvement were the ankles (29 patients [76 percent]), pelvis (20 patients [53 percent]), and knees (16 patients [42 percent]); spine involvement was uncommon in this group of etretinate-treated patients. Involvement tended to be bilateral and multifocal. Fifteen (47 percent) of the 32 affected patients had no bone or joint symptoms at the sites of radiographic abnormality. Thus, tendon and ligament calcification can occur without vertebral involvement as well as in association with it (for example, as part of the spectrum of diffuse idiopathic skeletal hyperostosis). We have identified extraspinal tendon and ligament calcification as a toxic effect that is commonly associated with long-term etretinate therapy.
Supplementary Figure Legends 1-5 from Novel Estrogen Receptor-α Binding Sites and Estradiol Target Genes Identified by Chromatin Immunoprecipitation Cloning in Breast Cancer (2023)

Supplementary Figure Legends 1-5 from Novel Estrogen Receptor-α Binding Sites and Estradiol Target Genes Identified by Chromatin Immunoprecipitation Cloning in Breast Cancer