gebhart/patrepeval huggingface dataset:
Cambio climático y salud: la apuesta a la deliberación [Climate change and health: the bet on deliberation] (2021)

La compleja interacción entre las sociedades actuales y el medio ambiente es una importante línea de investigación que permitiría comprender cómo el modo de producción propio del modelo capitalista constituye una de las principales causas del calentamiento global y a su vez, como un efecto bumerang, dicho cambio climático ocasionaría afectaciones directas a la salud humana. A partir del análisis de esta compleja relación, el presente artículo busca proponer una alternativa, necesaria más no suficiente, con miras a construir relaciones más armónicas y sostenibles entre el ser humano y su ambiente, partiendo de la construcción de un modelo de ciudadanía orientada a propiciar espacios de participación efectiva para sectores vulnerables, particularmente, aquellos cuya salud y seguridad alimentaria se pueden ver afectadas por los efectos del cambio climático. Para tal efecto se acudió a un diseño metodológico de enfoque cualitativo que introdujo elementos interdisciplinares que combinaron elementos teóricos y metodológicos de la filosofía política y la sociología, empleando categorías como el metabolismo social, que permite trazar el impacto de la evolución humana y sus organizaciones políticas y sociales en relación con el ecosistema mundial a partir de sus fuentes energéticas.
Run-to-run control strategy for diabetes management (2005)

An approach to insulin injection therapy is introduced that draws from recent ideas in run-to-run control of batch chemical reactors. The method relies on measurements of blood glucose and does not require a mathematical model. Results are shown for simulation case studies involving a detailed pharmacokinetic model.
PAC: perceptive admission control for mobile wireless networks (2004)

Traditional approaches to guarantee quality of service (QoS) work well only with predictable channel and network access. In wireless mobile networks, where conditions dynamically change as nodes move about the network, a stateless approach is required. As wireless networks become more widely used, there is a growing need to support advanced services, such as multimedia streaming and voice over IP. Since shared wireless resources are easily over-utilized, the load in the network must be controlled so that an acceptable QoS for real-time applications can be maintained. If minimum real-time requirements are not met, these data packets waste bandwidth and hinder other traffic, compounding the problem. To address this issue, we propose the perceptive admission control (PAC) protocol. PAC monitors the wireless channel and dynamically adapts admission control decisions to enable high network utilization while preventing congestion. Through discussion and simulations, we show that PAC achieves this goal and ensures low loss and delay for all admitted flows.
Heterologous sensitization of human AC5: dependence on heterotrimeric G proteins (2010)

We investigated the role of heterotrimeric G proteins in heterologous sensitization of adenylyl cyclase type 5 (AC5). Although acute stimulation of Gαi‐coupled receptors inhibits AC5 activity, persistent receptor activation enhances AC5 activity. This phenomenon is known as heterologous sensitization of AC, and has been implicated in drug dependence. Previous work revealed an absolute requirement for Gαs in heterologous sensitization of AC5. To further elucidate the mechanism, we assessed sensitization in cells devoid of endogenous Gαs, co‐expressing the D 2L receptor, AC5, and Gαs mutants. Our data showed that AC5‐Gαs, but not Gβγ‐Gαs interactions or palmitoylation of Gαs, were required for heterologous sensitization of AC5. Next, we explored the role of Gβγ‐AC5 interactions in heterologous sensitization. Sequestering Gβγ with βARK‐ct partially attenuated heterologous sensitization. Deletion of a novel N‐terminal Gβγ interacting domain of AC5 abolishes Gβγ binding, but does not greatly alter other forms of acute regulation. However, the AC5 deletion mutant was selectively impaired in heterologous sensitization. Together, these studies support a complex model of heterologous sensitization of AC5 where Gαs is directly interacting with AC5. In contrast, Gβγ appears to have multiple and indirect roles in heterologous sensitization of AC5. Supported by P.U. and grants VJW‐MH060397 and CWD‐GM060419.
Orientation Imaging of Recrystallization, Grain Growth and Phase Transformations Using In-situ Heating (2005)

Extended abstract of a paper presented at Microscopy and Microanalysis 2005 in Honolulu, Hawaii, USA, July 31--August 4, 2005
Supplementary Table 1 from Targeting MARCO and IL37R on Immunosuppressive Macrophages in Lung Cancer Blocks Regulatory T Cells and Supports Cytotoxic Lymphocyte Function (2023)

&lt;p&gt;Patient characteristics&lt;/p&gt;
Hide-and-seek and other search games (2013)

In the game of hide-and-seek played between two players, a Hider picks a hiding place and a Searcher tries to find him in the least possible time. Since Isaacs had the idea of formulating this mathematically as a zero-sum game almost fifty years ago in his book, Differential Games, the&#13;\ntheory of search games has been studied and developed extensively. In the classic model of search games on networks, first formalised by Gal in 1979, a Hider strategy is a point on the network and a Searcher strategy is a&#13;\nconstant speed path starting from a designated point of the network. The Searcher wishes to minimise the time to find the Hider (the payoff), and the Hider wishes to maximise it. Gal solved this game for certain classes of networks: that is, he found optimal strategies and the payoff assuming&#13;\nbest play on both sides. Here we study new formulations of search games, starting with a model proposed by Alpern where the speed of the Searcher depends on which direction he is traveling. We give a solution of this game on a class of networks called trees, generalising Gal's work. We also show how the game relates to another new model of search studied by Baston and Kikuta, where the Searcher must pay extra search costs to search the network's nodes (or vertices). We go on to study another new model of search called expanding search, which models coal mining. We solve&#13;\nthis game on trees and also study the related problem where the Hider's strategy is known to the Searcher. We extend the expanding search game to consider what happens if there are several hidden objects and solve this game for certain classes of networks. Finally we study a game in which a&#13;\nsquirrel hides nuts from a pilferer.
Platelet bioreactor-on-a-chip (2014)

Platelet transfusions total >2.17 million apheresis-equivalent units per year in the United States and are derived entirely from human donors, despite clinically significant immunogenicity, associated risk of sepsis, and inventory shortages due to high demand and 5-day shelf life. To take advantage of known physiological drivers of thrombopoiesis, we have developed a microfluidic human platelet bioreactor that recapitulates bone marrow stiffness, extracellular matrix composition,micro-channel size, hemodynamic vascular shear stress, and endothelial cell contacts, and it supports high-resolution live-cell microscopy and quantification of platelet production. Physiological shear stresses triggered proplatelet initiation, reproduced ex vivo bone marrow proplatelet production, and generated functional platelets. Modeling human bone marrow composition and hemodynamics in vitro obviates risks associated with platelet procurement and storage to help meet growing transfusion needs.
Cyclooxygenase‐2 induction by adiponectin is regulated by a sphingosine kinase‐1 dependent mechanism in cardiac myocytes (2008)

The adipose-derived plasma protein, adiponectin (APN), has various protective effects on cardiovascular diseases. In this study, we show that endogenous APN is required for full cyclooxygenase-2 (COX-2) induction by ischemia-reperfusion injury in the heart in vivo. In rat neonatal cardiac myocytes, APN-induced COX-2 expression was reduced by treatment with a sphingosine kinase-1 (SphK-1) inhibitor or siRNA targeting SphK-1. Treatment with a sphingosine-1-phosphate (S1P) receptor antagonist also diminished COX-2 expression in response to APN stimulation. These findings suggest that APN is a physiological regulator of COX-2 signaling in the heart and that this regulation occurs in part via a SphK-1-S1P receptor dependent mechanism in cardiac myocytes.
Endoscopic Treatment of Extraforaminal Entrapment of L5 Nerve Root (Far Out Syndrome) by Unilateral Biportal Endoscopic Approach: Technical Report and Preliminary Clinical Results (2019)

We were able to achieve successful decompression of unilateral extraforaminal entrapment of the L5 nerve root using unilateral biportal endoscopic surgery. A unilateral biportal endoscopic approach may be considered as an alternative surgical treatment for far out syndrome.
On the use of pre-filters in quadrupole mass spectrometers (1991)

Computer simulation, based on real, circular-rod quadrupole geometry, is used for studying the effect of RF-only pre-filters on the performance of the quadrupole mass analyser. Although they were originally introduced to avoid undesirable fringing field effects, pre-filters have proven to be useful even if these effects are not taken into account. It is also shown, through the example of the He ion, that the fringe fields do not really play a significant role in the case of fast ions. Consequently, mass spectrometers supplied with pre-filters produce better performance than the analyser itself not only for higher masses, where the fringing field effects are considerable, but also for lower ones where they can be neglected. The intensity-pre-filter length curve has a definite maximum. The optimum pre-filter length belonging to this maximum value is found to be about 12% that of the main analyser used and yields nearly 100% higher transmission at a better resolution. It is shown that pre-filters of optimum size remarkably enlarge the effective inlet aperture of the main filter.
Effects of ramp time on sensory, motor and tolerance thresholds during exogenous electrical stimulation. (1991)

This investigation examined the effects of ramp time on the current intensity needed to elicit sensory, motor and pain tolerance response. Forty-seven healthy subjects were randomly divided into three groups. Subjects in group one (no. 17), group two (no. 15), and group three (no. 15) had the onset (ramp time) knob present at 1.0, 3.5 and 5.0 seconds, respectively. Subsequently, the wrist and finger flexors of the dominant hand were stimulated following standardized instructions. For each subject, the current intensity needed to elicit: (1) the sensory response, (2) minimum perceptible contraction, and (3) the maximum tolerance level of painful stimulation was determined. Significant F ratio was found for the current intensity at different perceptual level (p less than 0.5) but not for ramp time (p greater than .05). The findings suggest that with the stimulator used in this study, ramp time has no effect on the three basic excitatory responses, i.e., thresholds of sensory, motor and painful stimulation.
Photochemical reactions in a commerical poly(ether sulfone) (1977)

A commercial poly(ether sulfone) has been examined by electronic spectroscopy, continuous photolysis, and laser flash techniques. The spectroscopic experiments indicate that the chromophoric species primarily responsible for light absorption in the region 290–350 nm is the diphenyl sulfone unit. The laser flash experiments give direct evidence of bond scission at the ether linkage on the polymer backbone.
Supplementary Figure 2 from Efficacy of Levo-1-Methyl Tryptophan and Dextro-1-Methyl Tryptophan in Reversing Indoleamine-2,3-Dioxygenase–Mediated Arrest of T-Cell Proliferation in Human Epithelial Ovarian Cancer (2023)

Supplementary Figure 2 from Efficacy of Levo-1-Methyl Tryptophan and Dextro-1-Methyl Tryptophan in Reversing Indoleamine-2,3-Dioxygenase–Mediated Arrest of T-Cell Proliferation in Human Epithelial Ovarian Cancer
Fingerprint imaging with arrayed GHz PbTiO3 transducers (2022)

Fingerprint readers based on pMUTs using PZT and ScAlN are extensively studied. However, the resonance frequency of pMUTs is in the MHz range. In contrast, AlN transducers using the thickness extensional mode in the GHz range are an attractive approach to improve spatial resolution. However, the capacitive impedance of AlN transducer becomes high when the size of the acoustic source is reduced. To obtain small acoustic source with impedance matching, we proposed epitaxial PbTiO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</inf> (PTO) transducer. The relative dielectric constant of PTO is about 80, thus the spatial resolution can be further improved. Therefore, in this study, we conducted fingerprint imaging using PTO epitaxial thin films with a network analyzer, and we succeeded to acquire fingerprint images.
Systematic Overview of Warfarin and Its Drug and Food Interactions (2005)

The number of drugs reported to interact with warfarin continues to expand. While most reports are of poor quality and present potentially misleading conclusions, the consistency of reports of interactions with azole antibiotics, macrolides, quinolones, nonsteroidal anti-inflammatory drugs, including selective cyclooxygenase-2 inhibitors, selective serotonin reuptake inhibitors, omeprazole, lipid-lowering agents, amiodarone, and fluorouracil, suggests that coadministration with warfarin should be avoided or closely monitored. More systematic study of warfarin drug interactions in patients is urgently needed.
Supplementary Table S2 from A Novel Spectroscopically Determined Pharmacodynamic Biomarker for Skin Toxicity in Cancer Patients Treated with Targeted Agents (2023)

&lt;p&gt;Summary of cutaneous adverse events at the different time point for each patient included in this study. n/a: not available&lt;/p&gt;
Deployment challenges of femtocells in future indoor wireless networks (2011)

Femtocell technology is expected to improve both coverage and capacity, especially indoors. Providers of cellular services are increasingly implementing this technology in their networks. However, the decentralized manner of femtocells operation introduces several challenges. This paper presents an overview of the femtocells. It highlights the network requirements for deploying femtocells and discusses the major issues that affect their operation and performance. The paper also describes the key challenges of deploying femtocells and some of the proposed solutions. It then presents the future direction on applying optimization to enhance femtocell performance.
Hydrodynamics and Sound Generation of Low Speed Planar Jet (2008)

Hydrodynamics and sound radiation of a low speed planar jet with Re=3000 have been studied by large eddy simulation combined with Lighthill’s acoustic analogy. Jets evolving from both well-developed (parabolic) and undeveloped (top-hat) mean velocity profiles have been simulated. The results showed the following: (i) initial domination of a symmetrical mode for jets evolving from top-hat profiles and prevailing of an antisymmetrical mode resulting in a sinuous distortion of the potential core for jets evolving from parabolic profiles, and (ii) shape of a mean velocity profile has some effect on mean flow characteristics; however, the major differences were observed in the development of the fluctuations. Velocity fluctuations were significantly higher for jets evolving from a parabolic profile in the region beyond the end of the potential core before the flow reached a self-preserving state. To calculate the basic sound radiation, the sources in Lighthill’s equation were treated either as compact in all directions or as noncompact in the spanwise direction. The spanwise length of the computational domain was found to have a little effect on the results obtained with compact in all directions solution provided that spanwise length exceeds the correlation length. Results showed that the majority of sound was generated by the region beyond the end of the potential core.
Induction of IL-10 Suppressors in Lung Transplant Patients by CD4+25+ Regulatory T Cells through CTLA-4 Signaling (2006)

T cell-mediated autoimmunity to collagen V (col-V), a sequestered yet immunogenic self-protein, can induce chronic lung allograft rejection in rodent models. In this study we characterized the role of CD4+ CD25+ regulatory T cells (Tregs) in regulating col-V autoimmunity in human lung transplant (LT) recipients. LT recipients revealed a high frequency of col-V-reactive, IL-10-producing CD4+ T cells (T IL-10 cells) with low IL-2-, IFN-gamma-, IL-5-, and no IL-4-producing T cells. These T(IL-10) cells were distinct from Tregs because they lacked constitutive expression of both CD25 and Foxp3. Expansion of T IL-10 cells during col-V stimulation in vitro involved CTLA-4 on Tregs, because both depleting and blocking Tregs with anti-CTLA4 F(ab')2 mAbs resulted in loss of T IL-10 cells with a concomitant increase in IFN-gamma producing Th1 cells (TIFN-gamma cells). A Transwell culture of col-V-specific T IL-10 cells with Th1 cells (those generated in absence of Tregs) from the same patient resulted in marked inhibition of IFN-gamma and proliferation of T(IFN-gamma) cells, which was reversed by neutralizing IL-10. Furthermore, the T IL-10 cells were HLA class II restricted because blocking HLA class II on APCs resulted in the loss of IL-10 production. Chronic lung allograft rejection was associated with the loss of Tregs with a concomitant decrease in T IL-10 cells and an increase in T IFN-gamma cells. We conclude that LT patients have col-V-specific T cells that can be detected in the peripheral blood. The predominant col-V-specific T cells produce IL-10 that suppresses autoreactive Th1 cells independently of direct cellular contact. Tregs are pivotal for the induction of these "suppressor" T IL-10 cells.
Étude par RMN du 31P de l’hydrolyse des esters phosphoriques (1994)

La synthèse, par voie sol-gel, des matériaux silicatés met en jeu l’hydrolyse et la condensation d’alcoxydes de silicium Si(OR)4. L’extension de ce procédé aux matériaux phosphatés est délicate car les esters phosphoriques, PO(OR)3, sont très peu sensibles à l’hydrolyse. Cette étude suit, par RMN du 31P, révolution des différentes espèces, PO(OEt)3-x(OH)x (0 ≤ x ≤ 3), issues de l’hydrolyse des esters phosphoriques. Elle précise les conditions dans lesquelles cette hydrolyse peut s’effectuer. Une hydrolyse lente, mais significative est observée par chauffage sous reflux en présence d’acide sulfurique. Cet acide, qui joue un rôle particulier, entraine la dissociation des liaisons O-C plutôt que P-O favorisant ainsi la formation de groupements P-OH. Les meilleurs précurseurs pour la synthèse sol-gel de matériaux phosphatés devraient être les mono et di-esters (x = l ou 2).
Fast Estimation of Relative Poses for 6-DOF Image Localization (2015)

The 6-DOF (Degrees Of Freedom) image localization, which aims to calculate the spatial position and rotation of a camera, is a challenging task for location-based services. In existing approaches, this problem is often tackled by finding the matches between 2D image points and 3D structure points so as to derive the location information using direct linear transformation (DLT). However, these approaches may fail to localize images when the 3D structure points are not available, especially for massive data. To address this problem, this paper presents a novel data-driven approach for 6-DOF image localization. In this approach, we propose to localize an image according to the position and rotation information of multiple similar images retrieved from a large reference dataset. From the reference images, a fast relative pose estimation algorithm is proposed to derive a set of candidate poses for the input image. Since each candidate pose actually encodes the relative rotation and direction of the input image with respect to a specific reference image, we can thus fuse all these candidate poses so that the 6-DOF location of the input image can be efficiently derived through least-square optimization. Experimental results show that our approach performs comparable with GPS devices in image localization. In addition, the proposed relative pose estimation algorithm is much faster than existing work.
Lichens in the Environment as a Laboratory for Environmental and Science Education (2012)

Teachers are confronted with many issues regarding teaching and learning science. Currently Malaysian schools are facing difficulties in encouraging student to take up science in upper secondary. Student found science to be difficult and not enjoyable. Realizing this, alternative methods of teaching science have been proposed. Collaborative action research was carried out to work with teachers on how environment awareness and knowledge can be taught which would make students enjoy their learning and be informed about environmental knowledge. LICHEN study was proposed by a group of lecturers in measuring the quality of air by using simple apparatus which can be carried out outdoor. This paper reports as project work which was carried out collaboratively between university lecturers and teachers with their students. A teaching module using LICHEN to measure quality of air in the environment was designed by the science lecturers. Working collaboratively with faculty's lecturers, a group of teachers from 7 schools were selected to bring along 64 of their students to attend a project work and experience the use of LICHEN. Together with the students, school teachers conducted the experiment group. The experiment involved measuring the quality of air, measuring and observing the LICHEN then they have to carry out repeat and conducting three different areas to show the different air quality (near the roadside, pond and open space). Each group would present and display the result. At the end of the experiment the reaction from the teachers and students were very positive. They have gained the knowledge and valuable experimental competencies besides becoming more aware of the need to sustain the environment.
COMBUSTION MODELLING IN A BIOMASS-FED FURNACE (2009)

A comprehensive computational model for biomass combustion is presented, featuring a solid phase combustion model, a fluid dynamic model for the gas phase, and a solid particle transport and deposit formation model. It is implemented on a Finite Element code, and a test case is considered of a furnace burning wood particles. Results underline the capability of the code to predict combustion conditions and the growth rates of deposits of different particle size over the furnace walls, as well as the most critical locations for particle deposition.