gebhart/patrepeval huggingface dataset:
Specific complexation with mono- and disaccharides that can be detected by circular dichroism (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSpecific complexation with mono- and disaccharides that can be detected by circular dichroismKazuhiko Tsukagoshi and Seiji ShinkaiCite this: J. Org. Chem. 1991, 56, 13, 4089–4091Publication Date (Print):June 1, 1991Publication History Published online1 May 2002Published inissue 1 June 1991https://pubs.acs.org/doi/10.1021/jo00013a002https://doi.org/10.1021/jo00013a002research-articleACS PublicationsRequest reuse permissionsArticle Views829Altmetric-Citations154LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Contribution of the second stage of labour to pelvic floor dysfunction: a prospective cohort comparison of nulliparous women (2014)

VB resulted in prolapse changes and objective UI but not in increased self-report pelvic floor dysfunction at 6 months postpartum compared with women who delivered by CD prior to the second stage of labour. The second stage of labour had a modest effect on postpartum pelvic floor function.
Sequencing and analysis of megabase-sized genomic regions from wheat (2008)

International audience
Heterogenization of a Modified Grubbs–Hoveyda Catalyst on a ROMP‐Derived Monolithic Support (2003)

Abstract A ring‐opening metathesis polymerization‐ (ROMP‐) based monolith was synthesized using a Grubbs' first generation catalyst. The living termini were used for surface grafting of norborn‐5‐ene‐2‐ylmethyl hexafluoroglutarate. The free carboxylic acid groups of the graft polymer were converted into the corresponding silver salt and reacted with the Grubbs–Hoveyda catalyst [RuCl 2 (CH(2‐ i PrO)C 6 H 4 )(IMesH 2 )] (IMesH 2 = 1,3‐bis(2,4,6‐trimethylphenyl)‐4,5‐dihydroimidazol‐2‐ylidene) to yield a stable heterogeneous version of this catalyst for use in ring‐closing metathesis (RCM) under continuous flow conditions. The monolith‐supported Grubbs–Hoveyda catalyst. magnified image The monolith‐supported Grubbs–Hoveyda catalyst.
Chronologie der Wnt-Zielgenexpression und Visualisierung des nukleären β-Catenin/TCF-Komplexes (2007)

Der Wnt-Signalweg spielt in der Embryogenese und in der Homöostase adulter Stammzellsysteme eine wichtige Rolle. Über\ndie Kontrolle der Genexpression reguliert der Wnt-Signalweg die Proliferation, Differenzierung und Zelltypfestlegung.\nHier erfolgte erstmalig eine zeitaufgelöste Analyse der Wnt-Zielgenexpression. Beispielhaft wurde der zeitliche Verlauf\nder Expression von c-Myc, CCND1, CDKN1A, Ramp3, Plf/Mrp und TfR nach Aktivierung des Wnt-Signalwegs in der\nBrustdrüsenepithelzelllinie C57MG untersucht. Dabei zeigte sich, dass die Art der Signalweg-Aktivierung Auswirkungen\nauf Richtung, Stärke und den chronologischen Verlauf der Expression hat, und direkt sowie indirekt regulierte Gene\nunterschieden werden können.\nZudem konnte die Wnt-3a-induzierte Interaktion von endogenem β-Catenin und TCF-4 in C57MG-Zellen und in kolorektalen\nTumorzelllinien mit konstitutiv aktivem Wnt-Signalweg fluoreszenzmikroskopisch durch immunzytochemische Markierung in\nhoher Auflösung dargestellt werden.
Flux of surface‐active organic complexes of copper to the air‐sea interface in coastal marine waters (1996)

Concentrations of surface‐active organic complexes of copper in coastal seawater were used to estimate their transport from the water column to the air‐sea interface by molecular diffusion and bubble scavenging. Under average wind conditions observed in Massachusetts Bay, molecular diffusion to the air‐sea interface was the primary transport mechanism. Estimated diffusion flux rates ranged from 3.8 to 210 × 10 −17 mol Cu cm −2 s −1 , with a mean value of 62 × 10 −17 mol Cu cm −2 s −1 . Temporal variability in the flux rates was directly related to estimated rates of primary production, presumably due to the biological production of surface‐active organic matter within the bulk water. Flux rates due to bubble scavenging were generally 3 orders of magnitude less than those observed for diffusion, with a mean value of 2.3 × 10 −19 mol cm −2 s −1 for particulate Cu and 3.7 × 10 −19 mol cm −2 s −1 for dissolved Cu. Temporal variability of the estimated bubble‐mediated fluxes reflected sensitivity to changes in wind stress, as well as the variablility in concentration of the surface‐active forms of copper. Residence times of copper in the sea‐surface microlayer, based on a comprehensive estimate of the flux of copper from bulk water and atmospheric sources, ranged from 2 min during a phytoplankton bloom period to 21 min during the winter months. Estimates of the flux of surface active forms of copper from the water column to the air‐sea interface suggest that the entire inventory of copper within the surface mixed layer of Massachusetts Bay can be cycled through the microlayer within approximately 50 days. This is of the same timescale as the residence time of copper within the surface mixed layer of Massachusetts Bay, indicating that a major portion of copper within the surface mixed layer will be transported to the microlayer before removal from the mixed layer. The formation and transport of surface‐active forms of copper may significantly influence the biogeochemical behavior of copper, and, perhaps, other metals within the surface mixed layer.
Internet search for TV content based on TV Anytime (2004)

Television is one of the widely used media while Internet is a new and very fast developing interactive medium. The convergence of both leads to interactive television. One of the benefits of the interactive television is possibility to interactively search for TV content over Internet and create the electronic program guide (EPG) from the gathered information. The EPG is used for review of available programmes and for selection of interesting ones for recording or downloading from a video server. The paper describes possibilities of Internet search for TV content for digital interactive television based on TV-Anytime specifications. The described approach is an attempt how existing client-server search and a new dynamic and distributed search in peer-to-peer (P2P) networks could be combined together that both search concepts would benefit from each other. Because the search results are controlled by a client they are more reliable and with less fake information.
Effect of PCSO-524 on OA Biomarkers and Weight-Bearing Properties in Canine Shoulder and Coxofemeral Osteoarthritis (2015)

This study was designed to compare the therapeutic benefits of a compound of omega-3 fatty acids from the New Zealand green-lipped mussel (Perna canaliculus) (PCSO-524) and omega-3 fatty acids in fish oil on clinical outcomes and osteoarthritis biomarkers (chondroitin sulfate WF6 epitope) in 66 dogs that had osteoarthritis (OA); 39 dogs with OA hip joints, 15 dogs with OA shoulder joints and 12 dogs with OA shoulder and hip joints. The animals were presented at the Small Animal Hospital, Faculty of Veterinary Science, Chulalongkorn University. The dogs were allocated into two groups randomly. One group received PCSO-524 (n = 33) and the other group received fish oil (n = 33), administered orally for 24 weeks. Serum OA biomarkers (WF6), lameness scores, weight-bearing scores, range of motion (ROM) and peak vertical force gait analysis were evaluated before treatment and two, four, eight, 12, 16, 20 and 24 weeks after the treatment began. The mean of serum WF6 of the PCSO-524 group (262.46±118.06 ng/ml) was significantly (p<0.05) less than that of the fish oil group (324.76±133.65 ng/ml) after 24 weeks of administration. The lameness scores, weight-bearing scores, peak vertical force gait analysis results and ROM improved significantly within two weeks after the administration of PCSO-524 began, while there was no statistically significant improvement in any of the parameters of the fish oil group after 12 weeks. After week four, the lameness and weight-bearing scores and gait analysis results of the PCSO-524 group improved significantly by comparison with the fish oil group. In conclusion, the PCSO-524 administration led to good clinical outcomes and laboratory results of osteoarthritis of the shoulder and hip joints in dogs.
Minimum Scan Cover and Variants: Theory and Experiments (2022)

We consider a spectrum of geometric optimization problems motivated by contexts such as satellite communication and astrophysics. In the problem Minimum Scan Cover with Angular Costs , we are given a graph G that is embedded in Euclidean space. The edges of G need to be scanned, i.e., probed from both of their vertices. To scan their edge, two vertices need to face each other; changing the heading of a vertex incurs some cost in terms of energy or rotation time that is proportional to the corresponding rotation angle. Our goal is to compute schedules that minimize the following objective functions: (i) in Minimum Makespan Scan Cover (MSC-MS), this is the time until all edges are scanned; (ii) in Minimum Total Energy Scan Cover (MSC-TE), the sum of all rotation angles; and (iii) in Minimum Bottleneck Energy Scan Cover (MSC-BE), the maximum total rotation angle at one vertex. Previous theoretical work on MSC-MS revealed a close connection to graph coloring and the cut cover problem, leading to hardness and approximability results. In this article, we present polynomial-time algorithms for one-dimensional (1D) instances of MSC-TE and MSC-BE but NP-hardness proofs for bipartite 2D instances. For bipartite graphs in 2D, we also give 2-approximation algorithms for both MSC-TE and MSC-BE. Most importantly, we provide a comprehensive study of practical methods for all three problems. We compare three different mixed-integer programming and two constraint programming approaches and show how to compute provably optimal solutions for geometric instances with up to 300 edges. Additionally, we compare the performance of different meta-heuristics for even larger instances.
Superior Antibacterial Activity of Integral Lemon Pectin Extracted via Hydrodynamic Cavitation (2020)

Pectin extracted via hydrodynamic cavitation in water only from waste lemon peel and further isolated via freeze drying displays significant antibacterial activity against <i>Staphylococcus aureus</i>, a Gram positive pathogen which easily contaminates food. The antibacterial effect of the new IntegroPectin is largely superior to that of commercial citrus pectin, opening the way to advanced applications of a new bioproduct now obtainable in large amounts and at low cost from citrus juice industry's waste.
Evolution and Virulence of Serogroup 6 Pneumococci on a Global Scale (2002)

To study the evolution and virulence of pneumococcal populations, we used multilocus sequence typing to identify the major clones among 212 carriage and invasive isolates expressing capsular serogroup 6 from 39 countries. The global population consisted of 8 major complexes and 6 minor complexes of related clones and 32 clones of diverse origin. Surprisingly, serotype 6A clones evolved by mutation nearly as often as by recombination, whereas serotype 6B clones evolved almost exclusively by recombination (P = 0.0029). This is the first report of population genetic differences among serotypes of this species. The largest clonal complex was associated with invasive disease (P = 0.019) and included a common ancestor for five previously identified drug-resistant clones. The putative ancestors of the major clonal complexes were represented by a greater proportion of carriage isolates than were their descendents (P = 0.001), and the ancestors tended to be less virulent than their descendents in a mouse model of infection. These data suggested that virulent serogroup 6 clones have evolved multiple times from less-virulent ancestral clones.
Thermal conductivity of filled epoxy resins. (1989)

各種の充てん材を分散させたエポキシ樹脂の有効熱伝導率を測定し、 充てん材の種類、 体積分率、 粒子形状、 粒子配向状態との関係を調べた。 さらに、 粒子が均一にランダムに分散している場合につき、 有効熱伝導率を推定するための代表的な理論との比較を行った。
Synthesis, Characterization, and Electrochemical Studies of β,β‘-Fused Metallocenoporphyrins (2007)

Beta,beta'-Fused monoruthenocenylporphyrins, Cp*Ru(III)[1,2-[M(II)-5,10,15,20-tetrakis(3,5-di-tert-butylphenyl)-porphyrinato]-3-methyl-cyclopentadienide] (M = Ni (20), Cu (21), Zn (22)), and bisferrocenoporphyrins, Fe(II) bis[1,2-[M(II)-5,10,15,20-tetraphenylporphyrinato]-3-methyl-cyclopentadienide] (M = Ni (24), Cu (25), Zn (26)), were synthesized and characterized. A novel synthetic approach to beta,beta'-fused porphyrins through Pd(0)-catalyzed [3 + 2] cycloaddition was implemented in this work. UV-vis spectra of these compounds show largely broadened and red-shifted bands (relative to their precursors) indicating potential electronic communication between the attached organometallic moiety and the porphyrin core. The electrochemistry of these molecules suggests significant electronic interactions between the metallocene and metalloporphyrin in molecules 20 and 24. The crystal structure of the bisferrocenoporphyrin 26, Fe(II) bis[1,2-[Zn(II)-5,10,15,20-tetraphenylporphyrinato]-3-methyl-cyclopentadienide], was determined: [Cp2Fe[ZnTPP(THF)]2][Cp2Fe[ZnTPP(THF)ZnTPP(MeOH)]].3MeOH.6THF, M = 3804.35, monoclinic, space group P21/c, a = 33.327(5) A, b = 19.145(3) A, c = 29.603(5) A, beta = 106.309(2) degrees , V = 18128(5) A3, Z = 4. In this molecule, one porphyrin ring is rotated by about 72 degrees with respect to the other in the 5-fold axis of the Cp ring.
Microwave Anisotrophy Probe Launch and Early Operations (2013)

The Microwave Anisotropy Probe (MAP), a follow-on to the Differential Microwave Radiometer (DMR) instrument on the Cosmic Background Explorer (COBE), was launched from the Kennedy Space Center at 19:46:46 UTC on June 30, 2001. The powered flight and separation from the Delta II appeared to go as designed, with the launch placing MAP well within sigma launch dispersion and with less than 7 Nms of tip-off momentum. Because of this relatively low momentum, MAP was able to acquire the sun within only 15 minutes with a battery state of charge of 94%. After MAP's successful launch, a six week period of in-orbit checkout and orbit maneuvers followed. The dual purpose of the in-orbit checkout period was to validate the correct performance of all of MAP's systems and, from the attitude control system (ACS) point of view, to calibrate the performance of the spacecraft ACS sensors and actuators to maximize system performance. In addition to the checkout activities performed by the MAP team, the other critical activity taking place during the first six weeks after launch were a series of orbit maneuvers necessary to get the spacecraft from its launch orbit out to its desired orbit about L2, the second Earth-Sun Lagrange point. As MAP continues its standard operations, its ACS design is meeting all of its requirements to successfully complete the mission. This paper will describe the launch and early operations summarized above in greater detail, and show the performance of the attitude control and attitude determination system versus its requirements. Additionally, some of the unexpected events that occurred during this period will be discussed, including two events which dropped the spacecraft into its Safehold Mode and the presence of an anomalous force observed during each of the perigee orbit maneuvers that had the potential to cause these critical maneuvers to be prematurely aborted.
A nuclear Overhauser enhancement study on the imino proton resonances of a DNA pentadecamer comprising the specific target site of the cyclic AMP receptor protein in the ara BAD operon (1984)

A 500 MHz 1H-NMR study on a synthetic DNA pentadecamer comprising the specific target site of the cAMP receptor protein in the ara BAD operon is presented. Using pre-steady state NOE measurements, unambiguous assignments of all the imino proton resonances and associated adenine (H2) resonances are obtained. From the NOE data interbase pair interproton distances involving the imino and adenine (H2) protons are determined. It is shown that these distances are very similar to those expected for classical B DNA (RMS difference of 0.5 A), but are significantly different from those expected for classical A DNA (RMS difference of 1.1 A).
Construction and Evaluation of the Integrated Perception Ecological Environment Indicator (IPEEI) Based on the DPSIR Framework for Smart Sustainable Cities (2020)

Ecological environment evaluation is of great significance to achieve the Sustainable Development Goals (SDGs) and promote the harmonious development of economy, society, and environment. To evaluate environmental SDGs, single environmental indicators have been analyzed at national or large regional scale in some literature, while the urban integrated environment is ignored. Therefore, it is necessary to systematically and quantically evaluate the sustainability of ecological environment integrating the water, soil, and air environment at the urban scale. This study aims to construct the Integrated Perception Ecological Environment Indicator (IPEEI) based on the Driver-Pressure-State-Impact-Response (DPSIR) framework to solve the above-mentioned problems. The IPEEI model was proposed based on the three-level association mechanism of the Domain-Theme-Element, and the DPSIR framework conforming to the relevant standards for indicator determination. Moreover, the multi-dimensional, multi-thematic, and multi-urban quantitative evaluations were conducted using the entropy weight method, and the comprehensive evaluation grades by the Jenks natural breaks classification method of the geospatial analysis. Nine cities in the Wuhan Metropolitan Area were selected as the experimental areas. The results were consistent with the Ecological Index and local government’s planning and measures, which demonstrated that IPEEI can be effectively verified and applied for the evaluation of urban ecological environment sustainability.
Sequence design and evaluation of the reproducibility of water‐selective diffusion‐weighted imaging of the breast at 3 T (2014)

Diffusion measurements derived from breast MRI can be adversely affected by unwanted signals from abundant fatty tissues if they are not suppressed adequately. To minimize this undesired contribution, we designed and optimized a water-selective diffusion-weighted imaging (DWI) sequence, which relies on spectrally selective excitation on the water resonance, obviating the need for fat suppression. As this method is more complex than standard DWI methods, we also report a test-retest study to evaluate its reproducibility. In this study, a spectrally selective Gaussian pulse on water resonance was combined with a pair of slice-selective adiabatic refocusing pulses for water-only DWI. Field map-based shimming and manual determination of the center frequency were used for water selection. The selectivity of the excitation pulse was optimized by a spectrally selective spectroscopy sequence based on the same principles. A test-retest study of 10 volunteers in two separate visits was used to evaluate its reproducibility. Our results from all subjects showed high-quality diffusion-weighted images of the breast without fat contamination. Mean apparent diffusion coefficients for b = 0, 600 s/mm(2) and b = 50, 600 s/mm(2) all showed good reproducibility, as 95% confidence intervals of the apparent diffusion coefficients were 4 × 10(-5) mm(2) /s and 5 × 10(-5) mm(2) /s and repeatability values were 1.09 × 10(-4) and 1.31 × 10(-4) , respectively. In conclusion, water-selective DWI is a feasible alternative to standard methods of DWI based on fat suppression. The added complexity of the method does not compromise the reproducibility of diffusion measurements in the breast.
Production of Anthocyanin from Strawberry Cell Suspension Cultures; Effects of Sugar and Nitrogen (1994)

ABSTRACT Production of anthocyanins was investigated, controlling sugar concentration and ratio of ammonium: nitrate in culture medium of strawberry, Fragaria ananassa cv Shikinari. Anthocyanins were produced under 8000 lux for 2 wk using calli derived from suspension cultures of leaf tissues. Yield was greatest in modified LS medium containing 5% sucrose (W/V), a ratio of NH + 3 (2 mM):NO − 3 (28mM), 2,4‐dichlorophenoxyacetic acid and benzyladenine. Total anthocyanin was about 15 mg/100 mL of culture medium, almost six times greater than that in MS medium. Effects of sugars were also studied using eight sugars. Cell growth and anthocyanin accumulation were enhanced by glucose, sucrose, and fructose, but anthocyanin compositions were not affected. Major anthocyanins were peonindin‐3‐glucoside and cyanidin‐3‐glucoside. Peonidin‐3‐glucoside increased with an increase in the NH + 4 NO − 3 ratio at nitrogen concentration 30 mM, while that of cyanidin‐3‐glucoside changed vice versa .
Genomics of the Enteropathogenic Yersiniae (2014)

The study of the Y. pestis genome indirectly reveals enteric features of Y. pseudotuberculosis (and Y. enterocolitica). This chapter describes the salient features of postgenomic studies on Y. enterocolitica and Y. pseudotuberculosis and relates this to our understanding of the diversity and evolution of virulence for these species. The enteropathogenic yersiniae are ubiquitous in the environment, and are a common cause of animal infections, and they have been isolated from cattle, sheep, pigs, domesticated animals, and avian species. Various other adhesion- and invasion-associated factors such as Ail and the Myf fimbriae have also been reported in enteropathogenic yersiniae. B12 is an essential cofactor for several reactions, including 1,2-propanediol degradation. Although the true significance of tetrathionate respiration operon in Y. enterocolitica is unknown, in Salmonella, 1,2-propanediol is an important source of energy, and mutants unable to make B12 are significantly attenuated in their ability to grow in macrophages. With respect to the enteropathogenic yersiniae, the natural deselection highlights many known genes required for the enteropathogenicity by Y. pseudotuberculosis (and Y. enterocolitica), but also highlighted many previously unsuspected candidates. Perhaps the most striking aspect of the evolution of Yersinia is the extremely rapid emergence of Y. pestis from Y. pseudotuberculosis, and genome analysis shows how this has happened.