gebhart/patrepeval huggingface dataset:
Involvement of Transient Receptor Potential Vanilloid Channel 2 in the Induction of Lubricin and Suppression of Ectopic Endochondral Ossification in Mouse Articular Cartilage (2021)

Our findings demonstrate regulation of articular cartilage by TRPV2 through Prg4 induction and suppression of ectopic ossification.
Local Signals From Beyond the Receptive Fields of Striate Cortical Neurons (2003)

We examined in anesthetized macaque how the responses of a striate cortical neuron to patterns inside the receptive field were altered by surrounding patterns outside it. The changes in a neuron's response brought about by a surround are immediate and transient: they arise with the same latency as the response to a stimulus within the receptive field (this argues for a source locally in striate cortex) and become less effective as soon as 27 ms later. Surround signals appeared to exert their influence through divisive interaction (normalization) with those arising in the receptive field. Surrounding patterns presented at orientations slightly oblique to the preferred orientation consistently deformed orientation tuning curves of complex (but not simple) cells, repelling the preferred orientation but without decreasing the discriminability of the preferred grating and ones at slightly oblique orientations. By reducing responsivity and changing the tuning of complex cells locally in stimulus space, surrounding patterns reduce the correlations among responses of neurons to a particular stimulus, thus reducing the redundancy of image representation.
BRONX DERMATOLOGICAL SOCIETY (1938)

<h3>A Case for Diagnosis (Discoloration of the Cheeks and Neck). Presented by Dr. Leo Spiegel.</h3> Miss I. R., a typist aged 32, came to the clinic of the Lenox Hill Hospital because she had noticed that the skin of her face and neck was getting darker. This discoloration had increased gradually and become much more noticeable in the past two months. The patient has psoriasis, for which she has used siroil for a number of years with indifferent results. She states that for the past two years she has used a cold cream obtained from a large department store. This preparation was sold in 1 pound (453 Gm.) tin cans. No other cosmetic except rouge, used over the same period, had been applied to the face. The cold cream was applied only to remove the rouge. No history of ingestion of drugs could be obtained. The skin of the
Cortical functional connectivity networks in normal and spinal cord injured patients: Evaluation by graph analysis (2007)

The present work aims at analyzing the structure of cortical connectivity during the attempt to move a paralyzed limb by a group of spinal cord injured (SCI) patients. Connectivity patterns were obtained by means of the Directed Transfer Function applied to the cortical signals estimated from high resolution EEG recordings. Electrical activity were estimated in normals (Healthy) and SCI patients on twelve regions of interest (ROIs) coincident with Brodmann areas. Degree distributions showed the presence of few cortical regions with a lot of outgoing connections in all the cortical networks estimated irrespectively of the frequency band investigated. For both of the groups (SCI and Healthy), bilateral cingulate motor area (CMA) acts as hub transmitting information flows. The efficiency index, allowed to assert the ordered properties of such estimated cortical networks in both populations. The comparison of such estimated networks with those obtained from random networks, elicited significant differences (P < 0.05, Bonferroni-corrected for multiple comparisons). A statistical comparison (ANOVA) between SCI patients and healthy subjects showed a significant difference (P < 0.05) between the local efficiency of their respective networks. For three frequency bands (theta 4-7 Hz, alpha 8-12 Hz, and beta 13-29 Hz) the higher value observed in the spinal cord injured population entails a larger level of internal organization and fault tolerance. This fact suggests a sort of compensative mechanism as local response to the alteration in their MIF areas, which is probably due to the indirect effects of the spinal injury.
Distal regulatory elements required for rat whey acidic protein gene expression in transgenic mice. (1994)

Previous studies have demonstrated that a 3.0-kilobase, rat whey acidic protein (WAP) transgene containing 949 base pairs (bp) 5'- and 70 bp 3'-flanking DNA is expressed specifically in the mammary gland of transgenic mice in a copy number-dependent, position-independent manner (1). In order to localize the critical regulatory elements important for tissue-specific, high level WAP gene expression, DNase I hypersensitivity mapping studies of WAP transgenes were performed in nuclei isolated from mammary gland and liver. Two regions of DNase I hypersensitivity located at approximately -150 and -800 by from the site of transcription initiation, respectively, were detected only in nuclei isolated from the lactating mammary gland. Within the distal hypersensitive region several binding sites for members of the CTF/NFI family of transcription factors were identified using in vitro DNase I and dimethyl sulfate interference footprinting and electrophoretic mobility shift assays. Genomic footprinting established that such protein-DNA interactions occur preferentially in the lactating mammary gland. The analysis of several 5' deletion constructs identified the region between -853 and -729 bp as essential for WAP transgene expression. These results suggest that the distal DNase I hypersensitive region contains binding sites for CTF/NFI and plays a critical role in the regulation of WAP gene expression in transgenic mice.
[Determination of homoserine kinase activity by chromatographic separation and measurement of reaction products]. (1994)

A highly specific procedure for quantitative assay of the homoserine kinase activity in an optimized enzymatic reaction using 14C-labelled homoserine or [gamma 33P]-ATP as substrates, and paper or thin-layer chromatography for separation of the formed o-phosphohomoserine, is described. The procedure is simple, sensitive and allows the assay for the activity of both purified and non-purified homoserine kinases.
Plasmonic Au Nanopraticles Modified Nanopyramid-Arrays BiVO4with Enhanced Photoelectrochemical Activity (2019)

Gold nanoparticles (∼24 nm) were successfully loaded on the surface of BiVO4 nanopyramidal arrays by simple electrostatic self-assembly approach. By decorating gold nanoparticles on the surface of BiVO4 films, The photocurrent of as-prepared Au/BiVO4 photoanode increased from around 0.42 mA/cm2 for pristine BiVO4 to nearly 0.93 mA/cm2 at 1.23 vs. RHE under AM 1.5 illumination. The improved photoresponse of the Au/BiVO4 was found as a result from higher carrier generation and enhanced charge separation with the decoration of Au nanoparticles. The successful deposition provide a new route for desigining plasmonic photoanode and offers better understanding the photochemistry of noble metal-complex oxide heterostructures for photoelectrichemical water splitting.
Nanoemulsion Composite Microgels for Orthogonal Encapsulation and Release (2012)

Crosslinkable nanoemulsions are combined with flow lithography for the synthesis of structured composite microgels with controlled hydrophobic compartments. The microgels are used to demonstrate a number of motifs for controlled encapsulation and release of active compounds, including small molecules, proteins, and nanoparticles, from a single material platform. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Cloning and expression of the Escherichia coli glgC gene from a mutant containing an ADPglucose pyrophosphorylase with altered allosteric properties (1986)

A mutant strain of Escherichia coli K-12, designated 618, accumulates glycogen at a faster rate than wild-type strain 356. The mutation affects the ADPglucose pyrophosphorylase regulatory properties (N. Creuzat-Sigal, M. Latil-Damotte, J. Cattaneo, and J. Puig, p. 647-680, in R. Piras and H. G. Pontis, ed., Biochemistry of the Glycocide Linkage, 1972). The enzyme is less dependent on the activator, fructose 1,6 bis-phosphate for activity and is less sensitive to inhibition by the inhibitor, 5'-AMP. The structural gene, glgC, for this allosteric mutant enzyme was cloned into the bacterial plasmid pBR322 by inserting the chromosomal DNA at the PstI site. The glycogen biosynthetic genes were selected by cotransformation of the neighboring asd gene into an E. coli mutant also defective in branching enzyme (glgB) activity. Two recombinant plasmids, pEBL1 and pEBL3, that had PstI chromosomal DNA inserts containing glgC and glgB were isolated. Branching enzyme and ADPglucose pyrophosphorylase activities were increased 240- and 40-fold, respectively, in the asd glgB mutant, E. coli K-12 6281. The E. coli K-12 618 mutant glgC gene product was characterized after transformation of an E. coli B ADPglucose pyrophosphorylase mutant with the recombinant plasmid pEBL3. The kinetic properties of the cloned ADPglucose pyrophosphorylase were similar to those of the E. coli K-12 618 enzyme. The inserted DNA in pEBL1 was arranged in opposite orientation to that in pEBL3.
Spread Spectrum Signals for Digital Communications (2003)

Abstract Spread spectrum signals is a class of signals that were designed primarily for use in digital communication systems to overcome either intentional or unintentional interference. We begin by illustrating the basic elements of a spread spectrum digital communication system. Next, we consider the transmission of a binary information sequence by means of binary PSK. Later, we discuss frequency‐hopped (FH) spread spectrum. Finally, we close with a section on commercial spread spectrum systems.
An ultraviolet nanosecond light pulse generator using a light emitting diode for test of photodetectors (1997)

An optical function pulse generator that emits (1) short pulse of 1 ns duration, (2) double pulse with variable time interval, and (3) square waveform pulse of variable width in nanosecond range is devised using an InGaN/AlGaN double heterostructure light emitting diode (LED). Although the LED emits a 450 nm (blue) light under conventional dc operation below 30 mA, 380 nm light due to the InGaN/AlGaN component appears when a current larger than 50 mA is applied. This phenomenon is used to realize a pulsed ultraviolet light source. Under large nanosecond current pulsing (peak current &amp;gt;1 A), an intense pulsed emission of 380 nm is obtained. Pulse waveform of the LED emission can be adjusted electrically by applying a shaped current to the LED. To evaluate the potential of the pulse generator as a test source of photodetectors, the response waveforms of photomultiplier tubes were measured.
A Comprehensive Overview of Person Re-Identification Approaches (2020)

Person re-identification, identifying and tracking pedestrians in cross-domain monitoring systems, is an important technology in the computer vision field and of real significance for the construction of smart cities. With the development of deep learning techniques, especially convolutional neural networks, this technology has received more extensive attention and improvement in recent years and a large number of noteworthy achievements have emerged. This paper provides a comprehensive overview of person re-identification approaches to assist researchers in quickly understand this field with preference as well as to provide a more structured framework. By reviewing more than 300 re-identification related papers, the focus of these studies is summarized as information extraction, metric learning, post-processing, efficiency improvement, labeling cost reduction, and data type expansion. This classification is then organized based on different technologies, and on this basis, the pros and cons of each technology are analyzed. Moreover, this overview summarizes the difficulties and challenges of re-identification and discusses the possible research directions for reference.
Secondary voltage and stability control (2012)

Secondary voltage controls, as a non-cost voltage control, are often conducted by utilities as the first option to solve voltage violations. Utilities like PJM and MISO manually coordinate secondary voltage controls aiming at regulating voltage profile and avoiding the use of potentially costly controls, such as transmission loading relief or load shedding. The speed of secondary voltage control devices ranges from three up to 15 minutes, depending on the control mode (either automatic or manual). Increasing voltage stability has not (in the past) been considered as a control objective. In this paper, a novel decentralized secondary voltage control system is designed to automatically generate optimal control decisions meeting different control objectives (such as maximum stability margin, minimum controls and losses). The proposed system aims at providing fast and coordinated secondary voltage control decisions in the time range from several seconds to a few minutes. Comparative studies are performed between the proposed system and existing secondary voltage control approaches applied in utilities.
Design Development of High Temperature Manifold Converter Using Thin Wall Ceramic Substrate (1997)

&lt;div class="htmlview paragraph"&gt;This paper proposes a high temperature manifold converter with a thin wall ceramic substrate, such as; 4mil/400cpsi and 4mil/600cpsi. Double-wall cone insulation design was proposed for close-coupled converters to protect the conventional intumescent mat from high temperature. However, the double wall cone insulation is not applicable when the converter is directly mounted to the exhaust manifold without an inlet cone. The prototype manifold converter was tested under hot vibration test with a non-intumescent ceramic fiber mat and retainer rings as a supplemental support. The converter demonstrated durability for 10 hours under 80G acceleration and 100 hours under 60G acceleration with 1,050 °C catalyst bed temperature. The skin temperature of the heat shield was kept below 400 °C.&lt;/div&gt;
Coco: runtime reasoning about conflicting commitments (2016)

To interact effectively, agents must enter into commitments.What should an agent do when these commitments conflict?We describe Coco, an approach for reasoning about which specific commitments apply to specific parties in light of general types of commitments, specific circumstances, and dominance relations among specific commitments.Coco adapts answer-set programming to identify a maximal set of nondominated commitments.It provides a modeling language and tool geared to support practical applications.
A Novel Approach to Surge Control: High-Frequency Pressure Variance As an Indicator of Impending Surge in Centrifugal Compressors (2018)

This investigation studies fast-response pressure measurements as an indicator of the onset of surge in a single-stage centrifugal compressor. The objective is to determine an online monitoring approach for surge control that does not rely on surge margin relative to maps from predictions or factory testing. Fast-response pressure transducers are installed in the suction piping, inducer, diffuser, and discharge piping. A speed line is mapped, and high-speed pressure data are collected across the compressor map. The compressor is driven into surge several times to collect pressure data between during surge and between surge events. Following testing, these data are post-processed via filtration and statistical analyses. It is determined that, when taken together, the mean and range of the standard deviation of the time signal for multiple time steps can be used to determine whether the compressor’s operating point is approaching surge for the conditions tested.
Supplementary Table 3 from MAP Kinase-Interacting Kinase 1 Regulates SMAD2-Dependent TGF-β Signaling Pathway in Human Glioblastoma (2023)

Supplementary Table 3 from MAP Kinase-Interacting Kinase 1 Regulates SMAD2-Dependent TGF-β Signaling Pathway in Human Glioblastoma
Conformational Consequences of Regio‐ and Stereoselective Disulfide Bridge Oxidation in a Cyclic Peptide (2007)

Synthesis of thiosulfinates. A thiosulfinate moiety was introduced into a cyclic peptide by regio- and stereoselective disulfide-bridge oxidation of S2,S6-cyclo(H-Gly-Cys-Ser-Pro-Ala-Cys-Gly-OH). The CD, FTIR and NMR spectroscopic data demonstrated drastic changes in the peptide secondary structure upon oxidation of the Cys6 sulfur atom, while oxidation of the Cys2 sulfur atom caused only minor structure perturbations. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2268/2008/z700529_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Aberration correction in electron microscopy and spectroscopy (2021)

Aberration correction in electron microscopy has its origins in the work of Scherzer [1], who showed in 1936 that aberrations of round electron lenses are unavoidable and limit the attainable spatial resolution. In 1947, Scherzer went on to propose several approaches to counter the aberrations [2], and his proposals were followed by a period of design and building of aberration correctors. New correction principles were discovered and there were several successful 'proof of principle' correctors built, but the first successful correctors that improved the resolution of the microscopes they were built into were only introduced a half century later, in the late 1990s The long wait for eventual success made many people think that practical aberration correction may never work out.
A highly integrated dual-band triple-mode transmit IC for cellular CDMA2000 applications (2003)

A highly integrated transmit integrated circuit intended for dual-band (CELL/PCS) and triple-mode (CDMA/TDMA/AMPS) cellular mobile stations is presented. It features a linear-in-dB gain-control range of 90 dB and provides a high output power of 9 dBm (PCS band) while meeting linearity requirements (-53-dBc ACPR) and achieving the receive-band noise floor of -133 dBm/Hz. It consumes only 130-mA current (3-V supply) in the PCS band. A dynamic-biasing feature results in additional power savings at lower signal levels. The circuit is fabricated in a 30-GHz f/sub T/ BiCMOS technology.
Lateral impact noise isolation: motivation, methods, and mitigation (2016)

Impact noise isolation measurements and evaluation are traditionally defined and considered for vertical adjacencies exclusively, where the impact source is located in the space above the receiving room. ASTM E1007 has specific protocols, procedures and methods for the measurements and analysis of the data collected. However, impact noise transmission into the receiving room laterally adjacent to the source room (i.e., on the same floor) is important in some conditions (e.g., condominiums, apartments, and hotels). The existing standard provides no guidance for performing a lateral impact noise isolation measurement. The authors have developed methods and practices for performing this measurement. These are presented along with a selection of results demonstrating potential issues, criteria, and mitigation.
Antimonite is accumulated by the glycerol facilitator GlpF in Escherichia coli (1997)

In a search for genes responsible for the accumulation of antimonite in Escherichia coli, TnphoA was used to create a pool of random insertional mutants, from which one antimonite-resistant mutant was isolated. Sequence analysis showed that the TnphoA insertion was located in the glpF gene, coding for the glycerol facilitator GlpF. The mutant was shown to be defective in polyol transport by GlpF. These results suggest that in solution Sb(III) is recognized as a polyol by the glycerol facilitator.
Effects of Accelerometer Signal Processing Errors on Inertial Navigation Systems (2006)

Strapdown Inertial navigation systems consist of an inertial sensor assembly(ISA), electronic modules to process sensor data, and a navigation computer to calculate attitude, velocity and position. In the ISA, most gryoscopes such as RLGs and FOGs, have digital output, but typical accelerometers use current as an analog output. For a high precision inertial navigation system, sufficient stability and resolution of the accelerometer board converting the analog accelerometer output into digital data needs to be guaranteed. To achieve this precision, the asymmetric error and A/D reset scale error of the accelerometer board must be properly compensated. If the relation between the acceleration error and the errors of boards are exactly known, the compensation and estimation techniques for the errors may be well developed. However, the A/D Reset scale error consists of a pulse-train type term with a period inversely proportional to an input acceleration additional to a proportional term, which makes it difficult to estimate. In this paper, the effects on the acceleration output for auto-pilot situations and the effects of A/D reset scale errors during horizontal alignment are qualitatively analyzed. The result can be applied to the development of the real-time compensation technique for A/D reset scale error and the derivation of the design parameters for accelerometer board.
Ultrahigh-frequency loop antennas (1940)

ANTENNAS which are discussed in this paper were developed for two applications: (1) to serve as elements in radiating systems of localizers and radio ranges used to guide aircraft; (2) to act as receiving antennas carried by aircraft.
Manufacturing Cyclodextrin Fibers Using Water (2022)

Abstract Cyclodextrins are a class of biocompatible and highly water‐soluble oligosaccharide polymers, with vast applications in industries ranging from drug delivery to agriculture. Currently, most fiber production relies on using environmentally unfriendly organic solvents and polymeric additions. Cyclodextrins are seldom used on their own without a carrier polymer, however in this work, (2‐hydroxypropyl)‐ β ‐cyclodextrin) fibers are successfully produced with water, as the “green” solvent with pressurized gyration and electrospinning, without using a carrier polymer. The average fiber diameter of the pressurized gyration produces fibers ranged between 5.5 and 5.8 µm, while the average fiber diameter of the electrospun fibers ranged between only 183 and 305 nm. These findings show the thinnest diameter of pure cyclodextrin fibers achieved in current literature. Both techniques have specific advantages, such as electrospinning being able to produce nanofibers, while pressurized gyration has productivity of over 1.5 g min −1 . Here, a pioneering study into the production of cyclodextrin‐only fibers with two different fiber production techniques and the creation of a cyclodextrin‐super‐mat that combines both types of fibers is presented.
Biologically Responsive Polymeric Nanoparticles for Drug Delivery (2012)

Responsive nanoparticles that release their drug cargo in accordance with a change in pH or oxidative stress are of significant clinical interest as this approach offers the opportunity to link drug delivery to a specific location or disease state. This research news article reviews the current state of this field by examining a series of published articles that highlight the novelty and benefits of using responsive polymeric particles to achieve functionally-targeted drug delivery.