gebhart/patrepeval huggingface dataset:
(Invited) The Influence of Flux Changes on Semiconductor Nucleation and Crystal Growth from a Liquid Metal Electrode (2016)

This presentation will discuss the latest findings in regards to the concept of mediating nucleation and growth of a solute crystal inside a liquid metal electrode through heterogeneous electrochemical reduction reactions at the electrolyte/electrode interface. The focus will be to compare/contrast experimental and modeling data that pertain to the flux conditions that favor and inhibit nucleation and crystal growth steps. Two systems will be discussed. First, conditions that favor large-grain crystal growth from a bulk liquid pool electrode will be discussed. Second, flux conditions that permit a single crystal to grow from a microscopic liquid metal droplet will be presented. The possibility of using AC amperometry in both systems to initiate and affect crystal growth will also be discussed.
Electrochemical Micromachining (1995)

This article discusses the opportunities and challenges of through-mask electrochemical micromachining.
REOVIRUSES (1967)

Journal Article REOVIRUSES Get access N. F. STANLEY, D.Sc. N. F. STANLEY, D.Sc. Department of Microbiology, The University of Western Australia Perth, Western Australia Search for other works by this author on: Oxford Academic PubMed Google Scholar British Medical Bulletin, Volume 23, Issue 2, May 1967, Pages 150–154, https://doi.org/10.1093/oxfordjournals.bmb.a070536 Published: 01 May 1967
Secure delegation for distributed object environments (1998)

SDM is a Secure Delegation Model for Java-based distributed object environments. SDM extends current Java security features to support secure remote method invocations that may involve chains of delegated calls across distributed objects. The framework supports a control API for application developers to specify mechanisms and security policies surrounding simple or cascaded delegation. Delegation may also be disabled and optionally revoked. These policies may be controlled explicitly in application code, or implicitly via administrative tools.
Supplementary Figure 1A from Integrated Analysis Reveals Critical Genomic Regions in Prostate Tumor Microenvironment Associated with Clinicopathologic Phenotypes (2023)

&lt;p&gt;PDF file - 35K&lt;/p&gt;
Five-Year Follow-up of Patients Receiving Imatinib for Chronic Myeloid Leukemia (2006)

After 5 years of follow-up, continuous treatment of chronic-phase CML with imatinib as initial therapy was found to induce durable responses in a high proportion of patients. (ClinicalTrials.gov number, NCT00006343 [ClinicalTrials.gov].)
Prognostic value of the micronucleus assay for clinical endpoints in neoadjuvant radiochemotherapy for rectal cancer (2021)

We found consistent cytogenetic damage in lymphocytes after in-vivo RCT and in-vitro irradiation. Gender was confirmed as a well-known, and the PTV size was identified as a less well-known influencing variable on lymphocyte cytogenetic damage after partial-body irradiation. A consistent level of cytogenetic damage after in-vivo and in-vitro irradiation may indicate the importance of genetic factors for individual radiosensitivity. However, we found no evidence that in-vivo or in-vitro irradiation-induced cytogenetic damage is an adequate biomarker for the response to RCT in rectal cancer patients.
Zur Lipidzusammensetzung von Plankton als Futterquelle von Silber‐und Marmorkarpfen 1. Mitt. Fettsäurespektrum verschiedener Lipidklassen (1992)

Abstract Seit den 60er Jahren in verschiedenen Ländern Europas adaptierte Cyprinidenarten asiatischer Provenienz, speziell Silber‐ und Marmorkarpfen (Hypophthalmichthys molitrix und Aristichthys nobilis) sind zum einen aus fischereiwirtschaftlicher Sicht von ökonomischer und ökologischer Bedeutung [1]. Zum anderen sind diese Fischspezies infolge eines hohen Anteils polyenfettsäurereicher Triglyceride bei zugleich hoher Stückmasse und ernährungsphysiologisch günstiger Relation von n 3‐ zu n 6‐Polyenfettsäuren von gesundheitlichem Interesse bei der Prophylaxe und Therapie insbesondere von Herz‐Kreislauf‐Krankheiten [2–5]. Das war Veranlassung, zu untersuchen, inwieweit Zusammenhänge zwischen der Fettsäurekonstitution dominanter Lipidklassen dieser überwiegend Phyto‐ und Zooplankton fressenden Fische und ihrer spezifischen Ernährungsweise bestehen.
MXenes (2014)

Two-dimensional, 2D, materials, such as graphene, possess a unique morphology compared to their 3D counterparts, from which interesting and novel properties arise. Currently, the number of non-oxide materials that have been exfoliated is limited to two fairly small groups, viz. hexagonal, van der Waals bonded structures (e.g. graphene and BN) and layered transition metal chalcogenides. The MAX phases are a well established family of layered ternary transition metal carbides and/or nitrides, with a composition of M_[n+1]AX_n, where M is an early transition metal, A is one of A group elements, X is C and/or N; with n = 1, 2, or 3. The aim of this work is to exfoliate the MAX phases and produce 2D layers of transition metals carbides and/or nitrides by the selective etching of the A layers from the MAX phases. We labeled the resulting 2D M_[n+1]X_n layers "MXenes" to emphasize the loss of the A group element from the MAX phases and the suffix "ene" to emphasize their 2D nature and their similarity to graphene. The etching process was carried out using aqueous hydrofluoric acid at room temperature. Thirteen different MXenes were produced as a result of this work, viz., Ti₂C, Nb₂C, V₂C, Mo₂C, (Ti_[0.5],Nb_[0.5])₂C, (Ti_[0.5],V_[0.5])₂C, Ti₃C₂, (Ti_[0.5],V_[0.5])₃C₂, (V_[0.5],Cr_[0.5])₃C₂, Ti₃CN, Ta₄C₃, Nb₄C₃ and (Nb_[0.5],V_[0.5])₄C₃. The as-synthesized MXenes were terminated with a mixture of OH, O, and/or F groups. Sonicating MXenes resulted in separating the stacked layers to a small extent. When Ti₃C₂ was intercalated with dimethylsulfoxide, however, followed by sonication in water, large-scale delamination occurred, which resulted in aqueous colloidal solutions that could in turn be fabricated into MXene "paper". MXenes were found to be electrically conductive, hydrophilic and stable in aqueous environments, a rare combination indeed, with huge potential in many applications, from energy storage, to sensors to catalysts. This work focused on the use of MXenes as electrode materials in Li-ion batteries. They exhibited excellent capability to handle high cycling rates with good gravimetric capacities. The lithiation and delithiation were found to be due to redox intercalation/deintercalation reactions.
Anomalous responses of tumor vasculature to norepinephrine and prostaglandin E2 in the rabbit. (1977)

&lt;p&gt;Surface-dielectric-barrier discharges (SDBDs) can be applied for a wide range of applications, such as ozone generation, surface treatments, and air-pollutants removal. An important advantage of the SDBD plasma is that relatively low high-voltage (HV) pulses (&amp;lt;10 kV) are needed to generate the plasma. They are effective in removing a wide range of pollutants. Despite their high energy efficiency, plasma decomposition generally results in the reaction by-products and the formation of ozone and nitrogen oxides. This drawback can be overcome by combining the SDBD plasma with catalysis. In this paper, a novel plasma-catalytic topology is proposed for the purpose of on-demand air purification. The main idea of the plasma-catalytic reactor is that both the plasma and the catalytic function are configured as planar structures which are positioned in parallel to each other. The plasma is generated along a planar dielectric structure. We use an SDBD for this purpose. Plates coated with the catalytic material are positioned in parallel to the SDBD plates. The air to be treated is flushed along the plates. There are no restrictions to the type or combination of catalysts used; the catalysts and their specifications can be chosen freely. We have developed a modular plasma-catalytic SDBD reactor to handle large flows, which can be scaled up and scaled down easily. To energize the plasma, an SDBD power modulator was developed. The modulator is able to generate a HV output pulse over an SDBD plasma load with a magnitude adjustable from 4.78 to 6.95 kV. The pulse rise time is about 1μs and its ramp is about 6 kV/μs. The energy per pulse then ranges from 1.1 to 17.4 mJ. The output power can be adjusted up to 48 W at a repetition rate of 5.5 kHz. The maximum possible pulse repetition rate is 22 kHz, but it is limited to 5.5 kHz due to the limited current rating of the available dc power supply. The total energy efficiency of the power modulator is 68%. A single modulator unit can power up to two SDBD reactor plates of 100× 150 mm size, having plasma at both sides of the plate. The operational efficiency of the developed SDBD catalytic reactor has been investigated by studying the removal of NO\n &lt;sub&gt;x&lt;/sub&gt; and ethylene. The removal efficiency of NO\n &lt;sub&gt;x&lt;/sub&gt; and ethylene is determined as a function of energy density and operational parameters, such as their initial concentrations and the gas flow rate.\n &lt;/p&gt;
Viral Infections Activate Types I and III Interferon Genes through a Common Mechanism (2007)

Viral infections trigger innate immune responses, including the production of type I interferons (IFN-alpha and -beta) and other proinflammatory cytokines. Novel antiviral cytokines IFN-lambda1, IFN-lambda2, and IFN-lambda3 are classified as type III IFNs and have evolved independently of type I IFNs. Type III IFN genes are regulated at the level of transcription and induced by viral infection. Although the regulatory mechanism of type I IFNs is well elucidated, the expression mechanism of IFN-lambdas is not well understood. Here, we analyzed the mechanism by which IFN-lambda gene expression is induced by viral infections. Loss- and gain-of-function experiments revealed the involvement of RIG-I (retinoic acid-inducible gene I), IPS-1, TBK1, and interferon regulatory factor-3, key regulators of the virus-induced activation of type I IFN genes. Consistent with this, a search for the cis-regulatory element of the human ifnlambda1 revealed a cluster of interferon regulatory factor-binding sites and a NF-kappaB-binding site. Functional analysis demonstrated that all of these sites are essential for gene activation by the virus. These results strongly suggest that types I and III IFN genes are regulated by a common mechanism.
Atlas of Transcription Factor Binding Sites from ENCODE DNase Hypersensitivity Data Across 27 Tissue Types (2018)

Abstract There is intense interest in mapping the tissue-specific binding sites of transcription factors in the human genome to reconstruct gene regulatory networks and predict functions for non-coding genetic variation. DNase-seq footprinting provides a means to predict genome-wide binding sites for hundreds of transcription factors (TFs) simultaneously. However, despite the public availability of DNase-seq data for hundreds of samples, there is neither a unified analytical workflow nor a publicly accessible database providing the locations of footprints across all available samples. Here, we implemented a workflow for uniform processing of footprints using two state-of-the-art footprinting algorithms: Wellington and HINT. Our workflow scans the footprints generated by these algorithms for 1,530 sequence motifs to predict binding sites for 1,515 human transcription factors. We applied our workflow to detect footprints in 192 DNase-seq experiments from ENCODE spanning 27 human tissues. This collection of footprints describes an expansive landscape of potential TF occupancy. At thresholds optimized through machine learning, we report high-quality footprints covering 9.8% of the human genome. These footprints were enriched for true positive TF binding sites as defined by ChIP-seq peaks, as well as for genetic variants associated with changes in gene expression. Integrating our footprint atlas with summary statistics from genome-wide association studies revealed that risk for neuropsychiatric traits was enriched specifically at highly-scoring footprints in human brain, while risk for immune traits was enriched specifically at highly-scoring footprints in human lymphoblasts. Our cloud-based workflow is available at github.com/globusgenomics/genomics-footprint and a database with all footprints and TF binding site predictions are publicly available at http://data.nemoarchive.org/other/grant/sament/sament/footprint_atlas .
Increasing washing performance of wet-spun fibers (2016)

Purpose – The wet-spinning process is very important for the development and production of new lightweight design materials. The washing process is determined as one of the most cost-expensive part of wet spinning. The purpose of this paper is to show the development of a new washing concept. It proposes to increase the washing performance by decreasing fiber-fiber-interfaces during the washing process. Design/methodology/approach – For this purpose, conventional washing concepts are investigated by means of simulations and experiments to obtain process knowledge. Computational fluid dynamics simulation and particle image velocimetry measurements are used to investigate the process. Findings – The overall deficit in conventional washing methods is the large number of fiber-fiber-interfaces, which inhibit the solvent transport out of the compact fiber bundle. Therefore, a new washing concept with included water nozzles is developed. Based on the simulations and observations it is found that the arrangement of the nozzles has direct influence on the fanning of the fiber bundle. Originality/value – With increased fanning of the fiber bundle a more efficient solvent transport is expected. The developed washing box is a prosperous concept to achieve a higher washing performance during the wet-spinning process. The variable design of the washing box makes it possible to test different nozzle configurations and designs. In this paper the two most promising nozzle arrangements are shown and compared to each other.
Representation of Quantum Circuits with Clifford and $\pi/8$ Gates (2008)

In this paper, we introduce the notion of a normal form of one qubit quantum circuits over the basis $\{H, P, T\}$, where $H$, $P$ and $T$ denote the Hadamard, Phase and $\pi/8$ gates, respectively. This basis is known as the {\it standard set} and its universality has been shown by Boykin et al. [FOCS '99]. Our normal form has several nice properties: (i) Every circuit over this basis can easily be transformed into a normal form, and (ii) Every two normal form circuits compute same unitary matrix if and only if both circuits are identical. We also show that the number of unitary operations that can be represented by a circuit over this basis that contains at most $n$ $T$-gates is exactly $192 \cdot (3 \cdot 2^n - 2)$.
Polysaccharides as antiviral agents: antiviral activity of carrageenan (1987)

A number of polysaccharides showed good antiviral activity against several animal viruses. At 5 micrograms/ml, carrageenan prevented the cell monolayer from destruction by herpes simplex virus type 1 (HSV-1) growth. At 10 micrograms/ml, carrageenan reduced the formation of new infectious HSV-1 by almost five logs. No cytotoxic effects were detected with concentrations of carrageenan up to 200 micrograms/ml. When 10 micrograms of carrageenan per ml was added at the beginning of HSV-1 infection of HeLa cells, there was potent inhibition of viral protein synthesis, and the cells continued synthesizing cellular proteins. This did not occur if carrageenan was added 1 h after HSV-1 infection. The use of [35S]methionine-labeled virions to analyze the entry of HSV-1 or Semliki Forest virions into cells indicated that carrageenan had no effect on virus attachment or virus entry. Moreover, carrageenan did not block the early permeabilization of cells to the toxic protein alpha-sarcin. These results suggest that this sulfated polysaccharide inhibits a step in virus replication subsequent to viral internalization but prior to the onset of late viral protein synthesis.
The 14C method: Patterns of dark CO2 fixation and DCMU correction to replace the dark bottle1,2 (1983)

Subtracting dark 14 C fixation from light 14 C fixation can lead to serious underestimates of phytoplankton production in aquatic environments. Light, temperature, and nutrient time‐course experiments show that there is an active and an inactive incorporation component of 14 C in the dark. The active incorporation can be prevented by adding DCMU (dissolved in water) to either a light or a dark bottle, thus estimating the inactive component. It is therefore recommended that a DCMU treatment be subtracted from the standard light carbon dioxide fixation for accurate estimation of phytoplankton production.
Dynamic protein expression patterns during intraoral wound healing in the rat (2005)

Wound healing after cleft palate surgery is often associated with impairment of maxillary growth and dento-alveolar development. Wound contraction and scar tissue formation contribute strongly to these effects. In vitro studies have revealed that fibroblasts isolated during different phases of palatal wound healing show phenotypical differences. They change from a quiescent to an activated state and then partly back to a quiescent state. In this study, we evaluated the existence of fibroblast phenotypes at several time-points during palatal wound healing in the rat. Based on cytoskeletal changes (alpha-sma, vimentin, vinculin), integrin expression (alpha1, alpha2, alpha(v) and beta1) and changes in cellularity, we conclude that phenotypically different fibroblast populations are also present during in vivo wound healing. Alpha-sma and the integrin subunits alpha1 and alpha(v) were significantly up-regulated, and vinculin was significantly down-regulated, at early time-points compared to late time-points in wound healing. These changes point to an activated fibroblast state early in wound healing. Later in wound healing, these activated fibroblasts return only partially to the unwounded situation. These results strongly support the idea that different fibroblast populations with specific phenotypes occur in the course of palatal wound healing.
0.5-$\mu\hbox{m}$ CMOS Implementation of Analog Heart-Rate Extraction With a Robust Peak Detector (2008)

A robust high-accuracy analog-signal-processing 0.5-mum CMOS chip for real-time heart-rate (HR) extraction is presented. A novel peak-detector architecture is proposed and implemented to facilitate on-chip integration. The system is capable of processing electrocardiogram (ECG) signals with a peak-to-peak amplitude as low as 5 mV, without any prefiltering. Experimental results with prerecorded and real-time ECG signals have demonstrated the obtained R-R interval accuracy on the order of milliseconds. The system was also used to successfully extract HR intervals with Doppler radar. Such a system may significantly reduce ADC resolution and sampling speed requirements while providing high immunity to noise and DC offset drift.
Fluorescence resonance energy transfer (FRET) microscopy in living cells as a novel tool for the study of cytokine action (2005)

Fluorescence resonance energy transfer (FRET) microscopy was used to study interactions between proteins in intact cells. We showed that growth hormone (GH) causes transient homodimerization of GH receptors tagged with yellow or cyan fluorescent proteins. The peak of FRET signaling occurred 2 to 4 min after hormonal stimulation and was followed by a decrease in FRET signal. Repeating those experiments in cells pretreated with the inhibitor of internalization methyl-beta-cyclodextrin, or in potassium-depleted cells showed no difference in the kinetics of FRET signaling as compared with the non-treated cells, indicating that the decrease in FRET signal does not result from receptor internalization by the pathways inhibited by methyl-beta-cyclodextrin or potassium depleted but might occur by other pathways of internalization. Using a similar methodology, we also demonstrated that ovine placental lactogen (oPL) causes transient heterodimerization of GH and prolactin (PRL) receptors 2.5 to 3 min after oPL application. On the other hand, oGH or oPRL had no effect at all, further substantiating the finding the oPL, which lacks a specific receptor, acts in homologous systems by heterodimerization of GH and PRL receptors. We also demonstrated that both PRL and leptin (LEP) are capable of transactivation of the oncogenic receptors erbB2 and erbB3. Upon PRL or LEP stimulation of HEK-293T cells transfected with LEP or PRL receptors and erbB2 or erbB3, erbB proteins are first phosphorylated and then activate MAPK (erk1/erk2). However, the FRET experiments failed to document any evidence of a direct interaction between erbB2 and the PRL or LEP receptors, suggesting that erbB activation probably occurs via activated JAK2, translocated from the respective receptors to erbB2.
The use of coding and diversity combining for mitigating fading effects in a DS/CDMA system (1998)

Spatial diversity is an attractive technology to cope with the fading channel encountered in mobile communications. This paper presents novel closed analytical expressions of the bit-error rate (BER) achievable in a coherent binary phase-shift-keying (CBPSK) direct-sequence code-division multiple-access (DS/CDMA) system for any power delay profile and for either postdetection selection or maximal ratio combining (MRC). In particular, expressions for the cutoff rate R/sub o/ and for its related parameter D are also formulated in order to assess the system performance under the consideration of some channel coding schemes. Finally, an exemplary study is carried out in order to illustrate the behavior of a realistic space-diversity code-division multiple-access (CDMA) system according to the analytical expressions that have been derived.
The reliability of the Family-of-Origin Scale for adolescents. (1991)

The Family-of-Origin Scale (FOS), a 40-item, ten-subscale measure of family processes, exhibits promise for assessing adolescents' perceptions of family health. While initial research has suggested that the instrument demonstrates factorial validity, the reliability of the FOS for adolescents has not been established. The present study involved administering the FOS to 88 adolescents on two occasions, with a two-week interval between testings. The global FOS index and ten subscale scores demonstrated high test-retest reliability. Internal consistency reliability for the instrument was also high. When taken together with previous research, the current study's results suggest that the FOS for adolescents is psychometrically sound.
CENTRAL ADMINISTRATION OF ATRIAL NATRIURETIC FACTOR INHIBITS SALINE PREFERENCE IN THE RAT (1986)

Atrial natriuretic factors (ANFs), produced in myocytes of mammalian atria, exert potent natriuretic and diuretic actions in the kidney as well as a variety of other actions coordinated to normalize extracellular fluid volume. Recently, ANF-like immunoreactivity has been detected in the hypothalamus of the rat, and central administration of ANF has been shown to block dehydration-induced water intake. We describe here the ability of 0.2 and 2.0 nmol atriopeptin III to inhibit saline intake when infused into the third ventricle of conscious, salt-depleted rats; an effect that was dose-related and long-lasting (24 h). These studies provide further evidence for a central nervous system action of ANF, which, together with its established renal and adrenal actions, might be an important feature of the coordinated physiological control of fluid volume.