gebhart/patrepeval huggingface dataset:
Characterisation of the redox centers of ethylbenzene dehydrogenase (2021)

Ethylbenzene dehydrogenase (EbDH), the initial enzyme of anaerobic ethylbenzene degradation from the beta-proteobacterium Aromatoleum aromaticum, is a soluble periplasmic molybdenum enzyme consisting of three subunits. It contains a Mo-bis-molybdopterin guanine dinucleotide (Mo-bis-MGD) cofactor and an 4Fe-4S cluster (FS0) in the α-subunit, three 4Fe-4S clusters (FS1 to FS3) and a 3Fe-4S cluster (FS4) in the β-subunit and a heme b cofactor in the γ-subunit. Ethylbenzene is hydroxylated by a water molecule in an oxygen-independent manner at the Mo-bis-MGD cofactor, which is reduced from the Mo<sup>VI</sup> to the Mo<sup>IV</sup> state in two subsequent one-electron steps. The electrons are then transferred via the Fe-S clusters to the heme b cofactor. In this report, we determine the midpoint redox potentials of the Mo-bis-MGD cofactor and FS1-FS4 by EPR spectroscopy, and that of the heme b cofactor by electrochemically induced redox difference spectroscopy. We obtained relatively high values of > 250 mV both for the Mo<sup>VI</sup>-Mo<sup>V</sup> redox couple and the heme b cofactor, whereas FS2 is only reduced at a very low redox potential, causing magnetic coupling with the neighboring FS1 and FS3. We compare the results with the data on related enzymes and interpret their significance for the function of EbDH.
Real-time hand detection based on multi-stage HOG-SVM classifier (2013)

In this paper, we propose a real-time hand detection method with multi-stage HOG-SVM classifier. Unlike traditional methods based on learning which make decomposition of feature vector or combination of different types of features or classifiers, upon the division of background into several categories, we propose a multi-stage classifier which combines several SVM classifies each of which is trained to distinguish corresponding divisions of background and target. Furthermore, in order to improve speed performance, skin color information and integral histogram are also applied. Experiment results demonstrate that the proposed algorithm works well under multiple challenging backgrounds in real-time speed (16 frames per second).
The mechanisms of interhemispheric inhibition in the human motor cortex (2002)

Transcranial magnetic stimulation can be used to non-invasively study inhibitory processes in the human motor cortex. Interhemispheric inhibition can be measured by applying a conditioning stimulus to the motor cortex resulting in inhibition of the contralateral motor cortex. Transcranial magnetic stimulation can also be used to demonstrate ipsilateral cortico-cortical inhibition in the motor cortex. At least two different ipsilateral cortico-cortical inhibitory processes have been identified: short interval intracortical inhibition and long interval intracortical inhibition. However, the relationship between interhemispheric inhibition and ipsilateral cortico-cortical inhibition remains unclear. This study examined the relationship between interhemispheric inhibition, short interval intracortical inhibition and long interval intracortical inhibition. First, the effect of test stimulus intensity on each inhibitory process was studied. Second, the effects of interhemispheric inhibition on short interval intracortical inhibition and long interval intracortical inhibition on interhemispheric inhibition were examined. Motor evoked potentials were recorded from the right first dorsal interosseous muscle in 11 right-handed healthy volunteers. For interhemispheric inhibition, conditioning stimuli were applied to the right motor cortex and test stimuli to the left motor cortex. For short interval intracortical inhibition and long interval intracortical inhibition, both conditioning stimuli and test stimuli were applied to the left motor cortex. With increasing test stimulus intensities, long interval intracortical inhibition and interhemispheric inhibition decreased, while short interval intracortical inhibition increased. Moreover, short interval intracortical inhibition was significantly reduced in the presence of interhemispheric inhibition. Interhemispheric inhibition was significantly reduced in the presence of long interval intracortical inhibition when matched for test motor evoked potential amplitude but the difference was not significant when matched for test pulse intensity. These findings suggest that both interhemispheric inhibition and long interval intracortical inhibition are predominately mediated by low threshold cortical neurons and may share common inhibitory mechanisms. In contrast, the mechanisms mediating short interval intracortical inhibition are probably different from those mediating long interval intracortical inhibition and interhemispheric inhibition although these systems appear to interact.
DEVELOPMENT OF A RATIONAL DESIGN PROCEDURE FOR PAVEMENTS SUBJECTED TO FROST ACTION (2002)

Frost action is a major cause of pavement deterioration in northern climates. Modern analytical tools are commonly used to assess the adequacy of pavement structures with respect to the effect of traffic, but in most design methods, procedures to take environmental factors into consideration are still essentially empirical. The paper proposes a new method for the verification of pavement structures with respect to the effects of freezing and thawing. The method is based on the following steps: calculation of the mechanical and thermodynamic response of the pavement structure to traffic and climatic conditions; the use of the calculated responses to predict performance through distress specific models; comparison of the results to the specific project objectives; and, if the objectives are not met, the final step includes a decision tree to help enhance the pavement structure.
Design, synthesis and acaricidal activity of novel strobilurin derivatives containing pyrimidine moieties (2010)

The present work demonstrates that strobilurin derivatives containing pyrimidine moieties can be used as possible lead compounds for developing novel acaricides.
Absence of human chorionic somatomammotropin during pregnancy associated with two types of deletion (1986)

info:eu-repo/semantics/published
Implications of Worsening Renal Function Before Hospitalization for Acute Heart Failure (2022)

Admission WRF is common in AHF patients and is associated with an increased length of hospitalization, but not adverse in-hospital events, death, or HF readmission. Among those with admission WRF, biomarkers did not risk stratify for adverse events.
Flexible mini gamma camera reconstructions of extended sources using step and shoot and list mode (2016)

This work identifies CD acquisition protocols combined with LM-EM reconstruction as a prime candidate for the wider introduction of SPECT imaging with flexible mini gamma cameras in the clinical practice.
Silica‐Supported Dendrimer‐Palladium Complex‐Catalyzed Selective Hydrogenation of Dienes to Monoolefins (2006)

Abstract The selective hydrogenation of cyclic and acyclic dienes to monoolefins occurs under very mild conditions, in the presence of silica‐supported PAMAM‐Pd complexes. The activity and selectivity of this reaction is sensitive to the dendrimer structure. These dendritic complexes display excellent recycle properties, retaining activity for up to eight recycles.
SIMULATION OF EDDY CURRENT INSPECTION INCLUDING MAGNETIC FIELD SENSOR SUCH AS A GIANT MAGNETO-RESISTANCE OVER PLANAR STRATIFIED MEDIA COMPONENTS WITH EMBEDDED FLAWS (2011)

The ECT inspection of a conductive component consists in detecting the perturbation of the induced currents due to a flaw. Among new detectors, Giant Magneto‐Resistance (GMR) or Giant Magnetic Impedance sensors, which are sensitive to the magnetic field above the surface of the component, have shown growing interest due to their high performances with respect to classical bobbin coils. In this communication, we present a numerical model based on the volume integral approach which allows computing the components of the perturbed magnetic field due to a given notch embedded in a planar stratified media. Though the inducer may be chosen arbitrary in a list of potential exciting coils, rectangular coils or current foils are very useful for generating a uniform current flow orientated perpendicularly to the length of the flaw. This paper presents firstly some numerical results considering two kinds of distinct numerical models, and then some experimental results will be presented for different kinds of practical applications. This numerical model results in new computation facilities which have been translated into new functionalities in the last version of the CIVA software.
Coherent combining of Q -switched fibre lasers (2004)

The power rising of an actively Q-switched erbium-doped fibre laser by using two coupled cavities with amplifying fibres in an interferometer configuration is reported. This study shows that the pulse peak power obtained is 1.7 higher than in a case of a unique laser. This concept brings some novel perspectives for scaling the output peak power of singlemode Q-switched fibre lasers.
Mannuronan C‐5 epimerases and cellular differentiation of Azotobacter vinelandii (2000)

Differentiation in Azotobacter vinelandii involves the encystment of the vegetative cell under adverse environmental circumstances and the germination of the resting cell into the vegetative state when growth conditions are satisfactory again. Morphologically, the encystment process involves the development of a protective coat around the resting cell. This coat partly consists of multiple layers of alginate, which is a copolymer of beta-D-mannuronic acid (M) and alpha-L-guluronic acid (G). Alginate contributes to coat rigidity by virtue of a high content of GG blocks. Such block structures are generated through a family of mannuronan C-5 epimerases that convert M to G after polymerization. Results from immunodetection and light microscopy, using stains that distinguish between different cyst components and types, indicate a correlation between cyst coat organization and the amount and appearance of mannuronan C-5 epimerases in the extracellular medium and attached to the cells. Specific roles of individual members of the epimerase family are indicated. Calcium and magnesium ions appear to have different roles in the structural organization of the cyst coat. Also reported is a new gene sharing strong sequence homology with parts of the epimerase-encoded R-modules. This gene is located within the epimerase gene cluster of Azotobacter vinelandii.
The Asp298Asn missense mutation in the porcine melanocortin-4 receptor (MC4R) gene can be used to affect growth and carcass traits without an effect on meat quality (2007)

A promising tool to improve daily gain in pigs is the missense mutation (Asp298Asn) in the melanocortin-4 receptor (MC4R) gene, especially in the Belgian pig industry where the slow-growing Piétrain breed is very frequently used as the sire breed. The MC4R is expressed in the appetite-regulating region of the brain where it regulates feed intake and energy balance. The mutation has been associated with differences in fatness, daily gain and feed intake. However, less information on the correlated effects on meat quality is available. In order to evaluate the influence of the MC4R mutation on carcass and meat quality parameters, a total of 1155 pigs of a four-way cross were slaughtered at an average live weight of 109 kg, and data about daily live-weight gain, carcass and meat quality were collected. Allelic frequencies were 0.69 for the G-allele (298Asp variant or well-conserved variant) and 0.31 for the A-allele (298Asn variant or the mutated variant). Barrows and gilts were almost equally distributed in this population with, respectively, 49.9% and 50.1%. Moreover, independent of this mutation, the relationship between average daily gain (ADG) and carcass on the one hand and meat quality traits on the other hand was evaluated in this population. A significant positive influence of the MC4R mutation on ADG (P < 0.001) was found, accompanied by a higher fat thickness (P < 0.05) and a lower carcass lean meat content (P < 0.01), whereas muscle thickness and carcass conformation traits were not affected. The effects on meat quality traits were not significant, except for a lower shear force (P = 0.054) and a higher intramuscular fat content (P = 0.052) in AA animals. In the longissimus, pH and pork quality meter (PQM) values were not influenced, and effects on drip loss and colour were not apparent. Residual correlation coefficients between ADG and carcass lean meat content on the one hand and meat quality traits on the other hand were generally very low (|r|>0.1). Higher ADG, higher carcass fat thickness and lower carcass lean meat content were correlated with slightly lower shear force values (|r|∼0.1, P < 0.05). In conclusion, in the studied population, the Asp298Asn mutation in the MC4R gene was associated with improved daily gain, higher carcass fatness and almost no effect on meat quality traits.
Sensitization of group III muscle afferents to static contraction by arachidonic acid (1990)

The afferent arm of the reflex are responsible for the pressor response to static contraction is comprised of group III and IV fibers. The nature of the contraction-induced stimulus activating these fibers remains unclear. Evidence suggests that most group III afferents are sensitive to mechanical stimuli, whereas most group IV afferents are sensitive to metabolic stimuli. Recently, in anesthetized cats, stimulation of group III mechanoreceptors has been shown to have a role in the reflex pressor response to static contraction. In skin, the sensitivity of thin fiber mechanoreceptors to distortion of their receptive fields has been shown to be increased by both cyclooxygenase and lipoxygenase products of arachidonic acid metabolism. Therefore, in barbiturate-anesthetized cats we recorded the responses of group III muscle afferents to static contraction before and after arachidonic acid (1-2 mg ia) and/or indomethacin (5 mg/kg iv). Arachidonic acid increased the responses of group III afferents (n = 11) to contraction by 265% (from 0.17 +/- 0.07 to 0.62 +/- 0.24 impulses/s; P less than 0.025). Indomethacin decreased the responses of group III afferents (n = 9) to contraction by 61% (from 1.00 +/- 0.37 to 0.39 +/- 0.16 impulses/s; P less than 0.025). Arachidonic acid given after indomethacin increased the responses of two of four group III afferents to contraction. We conclude that both cyclooxygenase and lipoxygenase products of arachidonic acid metabolism sensitize group III muscle afferents to static contraction.
Enhanced Light Emission from Monolayer MoS2 by Doubly Resonant Spherical Si Nanoantennas (2022)

Optical antennas provide a powerful tool to control local photonic environments and enhance light emission from two-dimensional transition-metal dichalcogenides. Dielectric nanoantennas with multipolar Mie resonances bring unique advantages for achieving simultaneous enhancement of the absorption and emission processes. Here, we achieve a strong modification of the photoluminescence (PL) behavior of monolayer MoS2 by a spherical nanoparticle (NP) of crystalline silicon (Si) that works as a double resonance nanoantenna. From theoretical calculations for in-plane dipoles placed beneath a Si NP nanoantenna with different sizes, we explore optimal conditions for the double resonances. Then, we develop a heterostructure composed of a Si NP and a monolayer MoS2 sheet with a comparable diameter and investigate the scattering, PL, and PL excitation spectra across a wide Si NP size range. We show that the spectral shape is significantly modified and PL intensity is enhanced up to ∼10-fold due to the coupling of the excitation process to the magnetic quadrupole resonance and the emission process to the magnetic dipole resonance.
Study on electromagnetic emission of DC SSR with transformer isolation (2009)

In this paper, the electromagnetic emission of a DC SSR (Solid State Relay) in which transformer isolation circuit was adopted was investigated at working frequency and higher harmonic. The equivalent circuit of dual-winding transformer of iron-core was proposed considering leakage inductance, iron loss in core and cupreous loss in winding. The EMC model of the DC SSR was built by Orcad Pspice and Ansoft QSD to predict electromagnetic radiation at the frequency from 10 kHz to 18 GHz which was prescribed in GJB 152A-RE102. The results of both simulation and experiment showed that the electromagnetic emission exceeded the limit of RE102. The electromagnetic emission of the DC SSR was divided into two parts: one generated by the inside circuit and another generated by external cables. And it was concluded that the electromagnetic emission was mainly generated by external cables. In order to improve EMC of SSR, an EMI filter was proposed to reduce the current in external cables so as to suppress the electromagnetic emission. The results showed this method was useful.
Cervical cancer cell lines expressing NKG2D-ligands are able to down-modulate the NKG2D receptor on NKL cells with functional implications (2012)

Our results suggest that differential expression of NKG2D-ligands in cervical cancer cell lines might be associated with the down-modulation of NKG2D, as well as with changes in the cytotoxic activity of NKL cells after cell-cell contact with the tumor cells.
Thermal radiation view factor calculation using Monte Carlo method. Comparison of accuracy and computer time with area integration method. (1988)

It is necessary to obtain the radiation geometric view factor for calculation of radiation heat transfer problems. There are many studies for calculation methods of the view factors such as area integration method, line integration method, Mitalas-Stephenson's contour integration method, Hottel's cross-string method and Monte Carlo method. The view factors can be calculated by area integration method and Monte Carlo method, even if third surface shading exists.The paper is comparative study of the calculation accuracy and computer time between area integration method and Monte Carlo method for view factors. It has been considered that Monte Carlo method is time consuming. However it is clarified from the calculation results of Monte Carlo method that a small amount of emission leads to reasonable view factors and small amount of emission leads to reasonable view factors and small amount of computer time.
Board 136: An Intersectional Perspective to Studying Microaggressions in Engineering Programs (2020)

Abstract Microaggressions are widespread in engineering but have received limited attention from engineering education scholars. This research presents the current state of literature on microaggressions and emphasizes the need to adopt an intersectionality perspective to studying mciroaggressions. The research presents a review of the literature including the (1) study context, (2) study methods, (3) study objectives, (4) microaggressions outcomes and (5) microaggressions types using data from 45 journal articles. Data analysis included coding of the journal articles to identify major themes representing different forms of microaggressions. The current results show that the research studying microaggressions using an intersectional lens is limited. This research contributes to improved understanding regarding microaggressions by identifying the gaps within existing literature on microaggressions. Practically, this research increases the visibility of subtle negative behaviors that engineering minority groups experience and their importance for students’ success and persistence.
COMBINING CLASSIFICATIONS BASED ON LOCAL AND GLOBAL FEATURES: APPLICATION TO SINGER IDENTIFICATION (2012)

In this paper we investigate the problem of singer identification on acapella recordings of isolated notes. Most of studies on singer identification describe the content of signals of singing voice with features related to the timbre (such as MFCC or LPC). These features aim to describe the behavior of frequencies at a given instant of time (local features). In this paper, we propose to describe sung tone with the temporal variations of the fundamental frequency (and its harmonics) of the note. The periodic and continuous variations of the frequency trajectories are analyzed on the whole note and the features obtained reflect expressive and intonative elements of singing such as vibrato, tremolo and portamento. The experiments, conducted on two distinct data-sets (lyric and pop-rock singers), prove that the new set of features capture a part of the singer identity. However, these features are less accurate than timbre-based features. We propose to increase the recognition rate of singer identification by combining information conveyed by local and global description of notes. The proposed method, that shows good results, can be adapted for classification problem involving a large number of classes, or to combine classifications with different levels of performance. 1.
A Bayes filter based adaptive floor segmentation with homography and appearance cues (2012)

This paper proposes a robust approach for image based floor detection and segmentation from sequence of images or video. In contrast to many previous approaches, which uses a priori knowledge of the surroundings, our method uses combination of modified sparse optical flow and planar homography for ground plane detection which is then combined with graph based segmentation for extraction of floor from images. We also propose a probabilistic framework which makes our method adaptive to the changes in the surroundings. We tested our algorithm on several common indoor environment scenarios and were able to extract floor even under challenging circumstances. We obtained extremely satisfactory results in various practical scenarios such as where the floor and non floor areas are of same color, in presence of textured flooring, and where illumination changes are steep.
LIGHTER-R: Optimized Reversible Circuit Implementation For SBoxes (2019)

This article presents the `LIGHTER-R' tool that aims at implementing a given 4-bit SBox using reversible logic libraries. An SBox is a basic building block in the symmetric key cryptography. In order to analyze the security of the symmetric key algorithms in the futuristic reversible computing paradigm, one needs to implement those algorithms in the reversible manner. Our tool offers an end-to-end flow for implementing a given 4-bit SBox (which is the common choice in recent designs) in reversible circuits while optimizing the cost for a given cost metric. It extends the tool LIGHTER, which is developed for classical computing. LIGHTER-R enjoys the advantages of LIGHTER; such as, easy to use and free.
Blocking blog spam with language model disagreement (2005)

We present an approach for detecting link spam common in blog comments by comparing the language models used in the blog post, the comment, and pages linked by the comments. In contrast to other link spam filtering approaches, our method requires no training, no hard-coded rule sets, and no knowledge of complete-web connectivity. Preliminary experiments with identification of typical blog spam show promising results.
Suppl Fig. 4 from Inhibiting Mitochondrial DNA Ligase IIIα Activates Caspase 1–Dependent Apoptosis in Cancer Cells (2023)

&lt;p&gt;Panel A. Induction of gammaH2AX foci in HeLa cells, HeLa Rho minus cells and HeLa cells expressing mitochondrially targeted E. coli DNA ligase by L67. Panel B. N-acetyl cysteine inhibits L67-induced autophosphorylation of ATM in HeLa cells.&lt;/p&gt;