gebhart/patrepeval huggingface dataset:
Planck 2015 results: XVII. Constraints on primordial non-Gaussianity (2016)

The Planck full mission cosmic microwave background (CMB) temperature and E-mode polarization maps are analysed to obtain constraints on primordial non-Gaussianity (NG). Using three classes of optimal bispectrum estimators-separable template-fitting (KSW), binned, and modal-we obtain consistent values for the primordial local, equilateral, and orthogonal bispectrum amplitudes, quoting as our final result from temperature alone localNL = 2.5 ± 5.7, equilNL=-16 ± 70, fNLlocal=2.5±5.7, fNLequil=-16±70, and orthoNL =-34 ± 32fNLortho=-34±33 (68% CL, statistical). Combining temperature and polarization data we obtain fNLlocal=0.8±5.0, fNLequil=-4±43, and fNLortho=-26±21localNL = 0.8 ± 5.0, equilNL=-4 ± 43, and orthoNL =-26 ± 21 (68% CL, statistical). The results are based on comprehensive cross-validation of these estimators on Gaussian and non-Gaussian simulations, are stable across component separation techniques, pass an extensive suite of tests, and are consistent with estimators based on measuring the Minkowski functionals of the CMB. The effect of time-domain de-glitching systematics on the bispectrum is negligible. In spite of these test outcomes we conservatively label the results including polarization data as preliminary, owing to a known mismatch of the noise model in simulations and the data. Beyond estimates of individual shape amplitudes, we present model-independent, three-dimensional reconstructions of the Planck CMB bispectrum and derive constraints on early universe scenarios that generate primordial NG, including general single-field models of inflation, axion inflation, initial state modifications, models producing parity-violating tensor bispectra, and directionally dependent vector models. We present a wide survey of scale-dependent feature and resonance models, accounting for the "look elsewhere" effect in estimating the statistical significance of features. We also look for isocurvature NG, and find no signal, but we obtain constraints that improve significantly with the inclusion of polarization. The primordial trispectrum amplitude in the local model is constrained to be glocalNL = (-0.9 ± 7.7) X 104(68% CL statistical), and we perform an analysis of trispectrum shapes beyond the local case. The global picture that emerges is one of consistency with the premises of the ΛCDM cosmology, namely that the structure we observe today was sourced by adiabatic, passive, Gaussian, and primordial seed perturbations.
‘Savoy’, an Adapted Soft Red Winter Wheat Cultivar for Georgia and the Southeast Regions of the United States (2017)

Soft red winter wheat (SRWW) ( Triticum aestivum L.) is a major crop in Georgia and the southeastern region of the United States. Despite a decrease of wheat acreages in this region, about 100,000 ha were grown to SRWW in Georgia in 2015. To capture and maximize regional market value of wheat, the new released cultivars must have high yield potential, excellent resistance levels to predominant diseases and insects, and good quality. Therefore, the major goal of the SRWW breeding program at the University of Georgia (UGA) is to develop and release SRWW cultivars adapted to the southeastern wheat region with high yield, quality, and pest resistance. ‘Savoy’ (Reg. No. CV‐1135, PI 676043) is a SRWW cultivar developed by the small grains breeding program at UGA in cooperation with the SUNGRAINS and released by the UGA College of Agricultural and Environmental Sciences in 2015. Savoy was subsequently licensed to CPS DYNA‐GRO Seed Company. Savoy was released because it is widely adapted to Georgia and the US Southeast. It has high grain yield, good resistance to races of leaf rust and stripe rust predominant in Georgia and the Southeast. Savoy possesses the H13 gene that confers resistance to predominant biotypes of Hessian fly in Georgia and the Southeast. It has good resistance to powdery mildew and Soil‐borne wheat mosaic virus . Savoy is moderately susceptible to Fusarium head blight, or scab. It also has high grain volume weight and acceptable SRWW milling and baking quality.
An Effective Approach to Continuous User Authentication for Touch Screen Smart Devices (2015)

Due to the rapid increase in the use of personal smart devices, more sensitive data is stored and viewed on these smart devices. This trend makes it easier for attackers to access confidential data by physically compromising (including stealing) these smart devices. Currently, most personal smart devices employ one of the one-time user authentication schemes, such as four-to-six digits, fingerprint or pattern-based schemes. These authentication schemes are often not good enough for securing personal smart devices because the attackers can easily extract all the confidential data from the smart device by breaking such schemes, or by keeping the authenticated session open on a physically compromised smart device. In addition, existing re-authentication or continuous authentication techniques for protecting personal smart devices use centralized architecture and require servers at a centralized location to train and update the learning model used for continuous authentication, which impose additional communication overhead. In this paper, an approach is presented to generating and updating the authentication model on the user's smart device with user's gestures, instead of a centralized server. There are two major advantages in this approach. One is that this approach continuously learns and authenticates finger gestures of the user in the background without requiring the user to provide specific gesture inputs. The other major advantage is to have better authentication accuracy by treating uninterrupted user finger gestures over a short time interval as a single gesture for continuous user authentication.
Geochemistry in the Search for Oil (1986)

RETURN TO ISSUEPREVNewsNEXTGeochemistry in the Search for OilR.PAUL PHILPView Author Information University of OklahomaCite this: Chem. Eng. News 1986, 64, 6, 28–43Publication Date (Print):February 10, 1986Publication History Published online7 November 2010Published inissue 10 February 1986https://pubs.acs.org/doi/10.1021/cen-v064n006.p028https://doi.org/10.1021/cen-v064n006.p028newsACS PublicationsCopyright © 1986 American Chemical SocietyArticle Views13Altmetric-Citations25LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options SUBJECTS:Lipids Get e-Alerts
Photoprocesses Involving Triplet States of Organic Crystals (1964)

First Page
Glucose availability regulates ghrelin‐induced food intake in the ventral tegmental area (2019)

Information about metabolic status arrives in the brain in the form of a complex milieu of circulating signalling factors, including glucose and fatty acids, ghrelin, leptin and insulin. The specific interactions between humoural factors, brain sites of action and how they influence behaviour are largely unknown. We have previously observed interactions between glucose availability and the actions of ghrelin mediated via the agouti-related peptide neurones of the hypothalamus. In the present study, we examine whether these effects generalise to another ghrelin-sensitive brain nucleus, the ventral tegmental area (VTA). We altered glucose availability by injecting mice with glucose or 2-deoxyglucose i.p. to induce hyperglycaemia and glucopenia, respectively. Thirty minutes later, we injected ghrelin in the VTA. Glucose administration suppressed intra-VTA ghrelin-induced feeding. Leptin, a longer-term signal of positive energy balance, did not affect intra-VTA ghrelin-induced feeding. 2-Deoxyglucose and ghrelin both increased food intake in their own right and, together, they additively increased feeding. These results add support to the idea that calculation of metabolic need depends on multiple signals across multiple brain regions and identifies that VTA circuits are sensitive to the integration of signals reflecting internal homeostatic state and influencing food intake.
Risk of Cardiovascular Disease in Patients with Nonalcoholic Fatty Liver Disease (2010)

Growing evidence suggests that nonalcoholic fatty liver disease is associated with an increased risk of cardiovascular disease beyond that conferred by established risk factors.
A Study of Multiple Folding Array Antennas on Satellite Installation and Radiation Characteristics after Deployment (2021)

A multiple folding array antenna that admits steps between panels, can furl and deploy using ordinary hinges and can realize two-dimensional deployment. In the deployed state, the steps should be compensated in phase to restore the antenna performance. However, the steps cannot be fully compensated out of the desired direction. In this paper, we study the antenna installation to a satellite and the radiation characteristics. It will be shown that the multiple folding array antenna is effective as an antenna for a small satellite.
Data from Dietary Genistein Inhibits Metastasis of Human Prostate Cancer in Mice (2023)

&lt;div&gt;Abstract&lt;p&gt;Dietary genistein has been linked to lower prostate cancer (PCa) mortality. Metastasis is the ultimate cause of death from PCa. Cell detachment and invasion represent early steps in the metastatic cascade. We had shown that genistein inhibits PCa cell detachment and cell invasion &lt;i&gt;in vitro&lt;/i&gt;. Genistein-mediated inhibition of activation of focal adhesion kinase (FAK) and of the p38 mitogen-activated protein kinase (MAPK)–heat shock protein 27 (HSP27) pathway has been shown by us to regulate PCa cell detachment and invasion effects, respectively. To evaluate the antimetastatic potential of genistein, we developed an animal model suited to evaluating antimetastatic drug efficacy. Orthotopically implanted human PC3-M PCa cells formed lung micrometastasis by 4 weeks in &gt;80% of inbred athymic mice. Feeding mice dietary genistein before implantation led to blood concentrations similar to those measured in genistein-consuming men. Genistein decreased metastases by 96%, induced nuclear morphometric changes in PC3-M cells indicative of increased adhesion (i.e., decreased detachment) but did not alter tumor growth. Genistein increased tumor levels of FAK, p38 MAPK, and HSP27 “promotility” proteins. However, the ratio of phosphorylated to total protein trended downward, indicating a failure to increase relative amounts of activated protein. This study describes a murine model of human PCa metastasis well suited for testing antimetastatic drugs. It shows for the first time that dietary concentrations of genistein can inhibit PCa cell metastasis. Increases in promotility proteins support the notion of cellular compensatory responses to antimotility effects induced by therapy. Studies of antimetastatic efficacy in man are warranted and are under way. [Cancer Res 2008;68(6):2024–32]&lt;/p&gt;&lt;/div&gt;
Addressing heterogeneity in the networked information environment (1996)

Several ongoing Stanford University Digital Library projects address the issue of heterogeneity in networked information environments. A networked information environment has the following components: users, information repositories, information services, and payment mechanisms. This paper describes three of the heterogeneity‐focused Stanford projects—InroBus, REACH, and DLITE. The InfoBus project is at the protocol level, while the REACH and DLITE projects are both at the conceptual model level. The InfoBus project provides the infrastructure necessary for accessing heterogeneous services and utilising heterogeneous payment mechanisms. The REACH project sets forth a uniform conceptual model for finding information in networked information repositories. The DLITE project presents a general task‐based strategy for building user interfaces to heterogeneous networked information services.
Net Production in Several Mature Plants Grown at Different Altitudes (1975)

The net productions of Polygonum reynoutria L. ssp. asiatica, Solidago virgaaurea L. ssp. asiatica, and Prunella vulgaris L. ssp. asiatica were measured by the leaf-half method modified monthly in several native habitats of different altitude. With P. reynoutria, the net productivity was decreased from late July to late September, and also was decreased in higher habitats. The productivities of S. virga-aurea and P. vulgaris, however, were increased from late July to late August, and from about 600m to about 1500m elevation in the same season, and then decreased in both cases. The temperature that showed the maximum productivity was lower in S. virga-aurea than in P. vulgaris. It was suggested that the plants distribution of these 3 species may be related to the difference in their productivities.
Differential patterning of cGMP in vascular smooth muscle cells revealed by single GFP-linked biosensors (2007)

Here, we report the design of unprecedented, non-FRET based cGMP-biosensors, named FlincGs, to assess the dynamics of nitric oxide (NO) and atrial natriuretic peptide (ANP) induced synthesis of intracellular cGMP, [cGMP](i). Regulatory fragments of PKG I alpha, PKG I beta, and an N-terminal deletion mutant of PKG I alpha were fused to circular permutated EGFP to generate alpha-, beta-, and delta-FlincG, with high dynamic ranges and apparent K(D,cGMP) values of 35 nM, 1.1 microM, and 170 nM, respectively. All indicators displayed significant selectivity for cGMP over cAMP, and 1.5- to 2.1-fold increases in fluorescence intensity at 510 nm when excited at 480 nm. Surprisingly, FlincGs displayed an additional excitation peak at 410 nm. delta-FlincG permitted ratiometric (480/410 nm) measurements, with a cGMP-specific 3.5-fold ratio change. In addition, delta-FlincG presented cGMP association and dissociation kinetics sufficiently fast to monitor rapid changes of [cGMP](i) in intact cells. In unpassaged, adenoviral transfected vascular smooth muscle (VSM) cells, delta-FlincG had an EC(50,cGMP) of 150 nM, and revealed transient global cGMP elevations to sustained physiological NO (EC(50,DEA/NO) = 4 nM), and the decay phase depended on the activity of PDE-5. In contrast, ANP elicited sustained submembrane elevations in [cGMP](i), which were converted to global cGMP elevations by inhibition of PDE-5 by sildenafil. These results indicate that FlincG is an innovative tool to elucidate the dynamics of a central biological signal, cGMP, and that NO and natriuretic peptides induce distinct cGMP patterning under the regulation of PDE-5, and therefore likely differentially engage cGMP targets.
The sustainable agenda and energy efficiency (2010)

Purpose This double special issue called for logistics solutions and supply chains in times of climate change. The purpose of this editorial is to investigate the current and future implications of climate change, and in particular, energy efficiency for logistics and supply chain management (SCM). Design/methodology/approach Against the backdrop of climate change, a conceptual framework is constructed that reflects on the immediate and tangible effects of a sustainable agenda on logistics and SCM. Findings Energy efficiency has been largely neglected in logistics and SCM. At the same time, considering energy efficiency requires considerable rethinking on the operational level (from transportation emissions to the cold chain) as well as even the conceptual level. The energy agenda needs a further development of logistics theory and practice. Originality/value The editorial highlights the challenges of sustainability and energy in the context of logistics and SCM pertaining to their novelty, importance and interdependence. SCM needs to develop new performance measures that include measures of energy efficiency, in order to adapt to an environment where the old assumption of low fuel costs does not hold stand.
A General Sub-Domain Boundary Mapping Procedure For Structured Grid CFD Parallel Computation (2007)

In the present work, a general sub-domain boundary mapping procedure has been developed for arbitrary topology multi-block structured grids with grid points matched on sub-domain boundaries. The interface of two adjacent blocks is uniquely deflned according to each local meshing index system (MIS) which is specifled independently. A pack/unpack procedure based on the deflnition of the interface is developed to exchange the data in 1D array to minimize the communication amount. A safe send/receive procedure is built to remove the possibility of communication block and achieve an optimum parallel computation e‐ciency. The procedure is applied to parallelize an in house 3D Navier-Stokes code. The message passing interface (MPI) protocol is used for the data communication. The implementation of this newly developed parallelization procedure is straightforward. The programming work to convert a sequential code to parallel code using this procedure is minimal. The numerical experiments on an MPI based computer cluster show that the general mapping algorithm is robust and has high parallel computation e‐ciency.
Lymphoma risk in systemic lupus: effects of disease activity versus treatment (2020)

To examine disease activity versus treatment as lymphoma risk factors in systemic lupus erythematosus (SLE).
Rôle liant des phosphates condensés dans les composites céramique-métal : application au système alumine-nickel (1991)

Nous presentons une etude du role liant de phosphates condenses vis-a-vis de deux oxydes : l'alumine et l'oxyde de nickel. La formulation 1,1 Na2O-1,9 MnO-3 P2O5 du metaphosphate a ete obtenue, en milieu aqueux, par le procede de coacervation des polyphosphates. Le coacervat est un polyelectrolyte inorganique. Nous en avons etudie la relation conformation des chaines de polyphosphates-temperature par rheologie et calorimetrie. La reactivite du coacervat du mangane��se-sodium intervient a la fois par des reactions par acidite de Bronsted, et par des reactions d'oxo-acidite. Le mecanisme reactionnel, conduisant a la formation du liant, a ete detaillee dans le cas des systemes coacervat de manganese-sodium/alumine et coacervat de manganese-sodium/oxyde de nickel. La modelisation de la reactivite coacervat-oxyde a ensuite ete appliquee a la realisation de composites alumine-nickel a liant phosphate. Ces composites sont destines a la fabrication d'elements chauffants par effet joule. Par le phenomene de percolation que presentent des particules de nickel dispersees dans une matrice en alumine, une resistivite elevee a ete obtenue pour ces materiaux. Un important pouvoir dissipatif de l'energie est lie a l'utilisation d'une matrice ceramique. Le liant a base de phosphates condenses permet une densification importante de la matrice a une temperature aussi moderee que 1000 °C. Les proprietes electriques requises n'ont pu etre obtenues que par un controle de la reactivite de la matrice avec les particules de nickel, ainsi que par la connaissance de l'interface metaphosphates-nickel
Direct Simulation of Transport in Open-Cell Metal Foams (2005)

Flows in porous media may be modeled using either a macroscopic approach, where volume-averaged semi-empirical equations are used to describe flow characteristics, or a microscopic approach, where small-scale flow details are simulated by considering the specific geometry of the porous medium. A direct simulation of the transport in an open-cell metal foam is carried out in the present study using a periodic unit cell. The foam geometry is created by assuming the pore to be spherical. The spheres are located at the vertices and at the center of the unit cell. The periodic foam geometry is obtained by subtracting the unit cell cube from the spheres. Fluid and heat flow are computed in the periodic unit cell. The objective of the present study is to obtain the effective thermal conductivity, pressure drop and local heat transfer coefficient from a consistent direct simulation of the open-cell foam structure. The computed values compare well with the existing experimental measurements and semi-empirical models. The results and the merits of the present approach are discussed.
Effectiveness of platelet transfusions after plasma exchange in adult thrombotic thrombocytopenic purpura: A report of two cases (2001)

Plasma infusion (PI) and plasma exchange (PE) are the most efficient treatment of thrombotic thrombocytopenic purpura (TTP), allowing achievement of complete remission in 60 to 90% of cases. Life-threatening bleeding, related to severe thrombocytopenia, is one of the main complications of the disease. Thrombocytopenia may also preclude invasive procedures such as splenectomy, which may be required during the management of TTP. Platelet concentrates transfusions are usually thought to worsen the disease, especially if not associated with the appropriate treatment of this latter, and thus should be avoided. We report hereon 2 patients with TTP who experienced a surgical procedure i.e., a cholecystectomy for a cholecystitis, and a splenectomy for a refractory TTP. In both patients, the surgical procedure was preceded by a 60 mL/kg plasma exchange with solvent/detergent treated plasma as replacement fluid, followed by platelet transfusion, with a corrected count increment of 57.1% (Patient 1) and 69.3% (Patient 2). Using this sequential treatment, the patients did not experience any deterioration of their status. Both patients had a favorable outcome after surgery. However, until such a procedure will be validated on a larger series of patients, it should be restricted to patients presenting with a refractory life-threatening thrombocytopenia and/or requiring surgery or any kind of invasive procedure. Am. J. Hematol. 68:198-201, 2001. Published 2001 Wiley-Liss, Inc.