gebhart/patrepeval huggingface dataset:
Real-time video mosaicking robust to dynamic scenes (2006)

This paper presents a system for creating a mosaic image from a sequence of images with moving objects present in the scene. This system first uses SIFT-based image registration on the entire image to obtain the initial global projection matrix. After image segmentation, the global motion model is applied to each region for evaluation. The transformation matrix is refined for best projection in each region, and a more precise global transformation matrix is calculated based upon local projections on majority of coherent regions. As a consequence this method is robust to disturbances to the projection model induced by moving objects and motion parallax. In the image blending stage, pixels in coherent regions are weighted by their distances from the overlapping edges to achieve a seamless panorama, while heterogeneous regions are cut and pasted to avoid ghosting or blurring. The most recent information regarding location, shape, and size of the moving foreground objects is therefore reflected in the panorama. Constructed mosaics are presented to demonstrate the performance and robustness of the proposed algorithm.
On the trail of fungal defense strategies – Employing a special workflow to spot photoactivity (2019)

Sunlight is not only a key factor for photosynthesis – the process enabling plants to convert solar energy into chemical energy [1] – but can also provide the basis for a winning defense strategy. Some plants, which are generally unable to actively flee from threats, use photons to fend off predators [2]. In detail, light-activated defense is based on the ability of certain pigments/photosensitizers, to produce reactive oxygen species (e.g. 1O2) after being exposed to light of a specific wavelength [3]. This led to the following hypothesis that fungi – another kingdom with “immobile” reproducing structures – might also possess highly photoactive compounds. To test this hypothesis, a previously established workflow [4] was used to rank the PDT-activity of several basidiomycetes.
Iteratively training classifiers for circulating tumor cell detection (2015)

The number of Circulating Tumor Cells (CTCs) in blood provides an indication of disease progression and tumor response to chemotherapeutic agents. Hence, routine detection and enumeration of CTCs in clinical blood samples have significant applications in early cancer diagnosis and treatment monitoring. In this paper, we investigate two classifiers for image-based CTC detection: (1) Support Vector Machine (SVM) with hard-coded Histograms of Oriented Gradients (HoG) features; and (2) Convolutional Neural Network (CNN) with automatically learned features. For both classifiers, we present an effective and efficient training algorithm, by which the most representative negative samples are iteratively collected to accurately define the classification boundary between positive and negative samples. The two iteratively trained classifiers are validated on a challenging dataset with high performance.
Einführung in die Ölhydraulik (1991)

Die Ölhydraulik hat dem Maschinenbaukonstrukteur völlig neue Möglichkeiten rur die Gestaltung seiner Maschinen und für die Verwirklichung neuer Konstruktionsideen er öffnet. Viele Funktionen, die früh
Application of Phosphoryl Oligosaccharides of Calcium (POs-Ca) for Oral Health (2004)

Phosphate ester groups are known to link to some glucosyl residues in starch molecules. We have prepared phosphoryl oligosaccharides (POs) from potato starch hydrolysates. The POs were composed of two fractions, PO-1 and PO-2. Fraction PO-1 was the main fraction, and it was composed of maltotriose, maltotetraose, and maltopentaose to which one phosphoryl group was attached. Fraction PO-2 was predominantly composed of maltopentaose and maltohexaose to which at least two phosphoryl groups were attached. POs had the ability to form a soluble complex with calcium and had an inhibitory effect on the formation of a calcium-phosphate precipitate. Based on the function of the POs, described above, we applied the POs of calcium (POs-Ca) as a food ingredient. POs-Ca was an advantageous food ingredient as a soluble calcium source. In relation to prevention of dental caries, POs cannot be fermented by cariogenic microorganisms or mutans streptococci, and they reduce the fall in plaque pH in vitro. Moreover, POs-Ca effectively enhanced the remineralization of enamel lesions. The aim of this study was to develop the application of POs-Ca for dental health to the enamel remineralization through the chewing of a sugar-free gum.
The interface of depression and cardiovascular disease: therapeutic implications (2015)

Patients with major depression are at an increased risk for developing cardiovascular disease, respond more poorly to treatment, and exhibit worse outcomes, including increased morbidity and mortality. This article reviews the relationship between depression and heart disease, with an emphasis on epidemiology, biological substrates that likely underlie this relationship, and implications for treatment.
Endothelial Progenitors: A Consensus Statement on Nomenclature (2017)

Endothelial progenitor cell (EPC) nomenclature remains ambiguous and there is a general lack of concordance in the stem cell field with many distinct cell subtypes continually grouped under the term "EPC." It would be highly advantageous to agree on standards to confirm an endothelial progenitor phenotype and this should include detailed immunophenotyping, potency assays, and clear separation from hematopoietic angiogenic cells which are not endothelial progenitors. In this review, we seek to discourage the indiscriminate use of "EPCs," and instead propose precise terminology based on defining cellular phenotype and function. Endothelial colony forming cells and myeloid angiogenic cells are examples of two distinct and well-defined cell types that have been considered EPCs because they both promote vascular repair, albeit by completely different mechanisms of action. It is acknowledged that scientific nomenclature should be a dynamic process driven by technological and conceptual advances; ergo the ongoing "EPC" nomenclature ought not to be permanent and should become more precise in the light of strong scientific evidence. This is especially important as these cells become recognized for their role in vascular repair in health and disease and, in some cases, progress toward use in cell therapy. Stem Cells Translational Medicine 2017;6:1316-1320.
Effect of plant origin insect growth regulators on emergence and survival of endoparasitic wasp, Apanteles obliqua (Hymenoptera: Braconidae) (2006)

The effect of diverse plant origin insect growth regulators on emergence and survival of endoparasitic Wasp, Apanteles obliqua (Hymenoptera: Braconidae) was studied in order to estimate the safety margins between the IGRs required to kill the pest and its parasitoid. The per cent adult emergence from the sprayed cocoons with IGR's was in the order of: CSM 1% (93.34%) > Aza 1% = CSH 1% (83.33%) > THA1% = MSH 1% = Neem oil (76.67%) > CSM 5% = CSH 5% (73.33%) > MSH 5% (56.67%) and the survival of the adults were: Aza = THA 1% = CSM 5% = CSM 1% (96.67%) > CSH 5% = CSH 1% = MSH 1% (73.33%) > MSH 5% = neem oil 1% (53.33), indicating safe use in IPM programme with exception to MSH 5% and neem oil 1%.
ATLÁNTIDA COLL-HURTADO, PREMIO GEOCRÍTICA 2014 (2014)

ES UN RECONOCIMIENTO A LOS TRABAJOS Y APORTACIONES DE
LOS INTEGRANTES DEL INSTITUTO DE GEOGRAFIA EN MAS DE SIETE DECADAS”, DIJO ATLANTIDA COLL- HURTADO, INVESTIGADORA EMERITA DE LA UNAM, SOBRE EL PREMIO INTERNACIONAL
GEOCRITICA 2014 OTORGADO POR LA RED GEOCRITICA INTERNACIONAL DE LA UNIVERSIDAD DE BARCELONA, ESPANA.
Detecting differential protein abundance by combining peptide level P -values (2020)

The majority of methods for detecting differentially abundant proteins between samples in label-free LC-MS bottom-up proteomics experiments rely on statistically testing inferred protein abundances derived from peptide ionization intensities or averaging peptide level statistics. Here, we statistically test peptide ionization intensities directly and combine the resulting dependent P-values using the Empirical Brown's Method (EBM), avoiding error introduced through the estimation of protein abundances or summarizing test statistics. We show that on a spike-in proteomics dataset, a peptide level approach using EBM outperforms differential abundance detection using a protein level approach and several analysis workflows, including MSstats. Additionally, we demonstrate the effectiveness of this approach by detecting enriched proteins from an activity-based protein profiling dataset.
Effect of Additional HCl Flow on the Surface Morphology of HVPE GaN on Sapphire (2002)

The polarity of GaN is known to be an important factor in determining the surface roughness and properties of the as grown material such as chemical reactivity. And precise control of the growth in polar direction is necessary to obtain low defect density materials as well as a specular surface. In this study, we obtained high quality GaN with smooth surface on sapphire by adding the additional HCl into the HVPE growth process. The result is attributed to the control of polarity of GaN films during growth. The additional HCl altered the equilibrium at the GaN growth front, and the reversible reaction decreased the nucleation density or growth rate. Further, lower growth rate promoted the surface diffusion and the coalescence over (0001) plane. Probably additional HCl improved the surface morphology by suppressing the (000 1) polarity growth in the initial stage of the growth.
Quantum bound states in narrow ballistic channels with intersections (1992)

A quantum-mechanical calculation is made of ballistic transport in intersecting narrow channels of finite length. The two-dimensional (2D) semiconductor structure we study consists of perpendicular channels, one of which connects to two reservoirs of 2D electron gas. These reservoirs serve as emitter and collectors when a potential difference is applied. At a single intersection with infinite leads, there are generally bound states that are well localized to the intersection area. In a structure with finite leads to emitter and collector, such localized states or quantum dots give rise to resonant tunneling. We show that in narrow ballistic channels with few stubs the bound states couple to each other. Therefore, the states at the different intersections combine as split bound states. The splitting is N-fold if there are N intersections. Here we study conductance in structures containing a few crossed-bar or T-shaped junctions and focus on the splitting of the resonance conductance below the first subband threshold. We argue that our results are in qualitative agreement with recent measurements. We also consider the spatial distribution of currents and show that a complicated flow pattern with vortex structures appears at higher energies.
1,4- and 2,6-Disubstituted Amidoanthracene-9,10-dione Derivatives as Inhibitors of Human Telomerase (1998)

A number of 1,4- and 2,6-difunctionalized amidoanthracene-9, 10-diones have been prepared. We have examined their in vitro cytotoxicity in several tumor cell lines and their ability to inhibit the telomere-addition function of the human telomerase enzyme together with their inhibition of the Taq polymerase enzyme. Compounds with -(CH2)2- side chains terminating in basic groups such as piperidine show inhibition of telomerase at telIC50 levels of 4-11 microM. These are thus among the most potent nonnucleoside telomerase inhibitors reported to date. Cytotoxicity levels in human tumor cell lines were at comparable levels for several compounds. Implications for amidoanthracene-9,10-dione telomerase inhibitors as potential anticancer agents are discussed.
Assessment of dental plaque coverage by Quantitative Light-induced Fluorescence (QLF) in domestic short-haired cats (2017)

Dietary means of reducing plaque and calculus deposits are frequently sought for the maintenance of oral health in cats and dogs. In the development of such products sensitive, reliable, reproducible methods of measuring plaque and calculus are key. The aim of this study was to assess Quantitative Light-induced Fluorescence (QLF™) for the detection of dental plaque coverage in cats compared to the modified Logan and Boyce technique. The techniques were utilised in a crossover study, which compared two diets for their effect on plaque deposition in a cohort of 24 adult cats. Analysis of the effect of diet on plaque coverage by both the modified Logan and Boyce technique and QLF showed a significant effect of feeding regime (p = 0.024 and p ≤ 0.0001, respectively) with good agreement between the techniques in the percentage reduction of plaque accumulation. A within study assessment of QLF demonstrated excellent intra-operator repeatability (coefficient of variation 2.2%). Similarly, inter-operator reproducibility was also good (coefficient of variation 2.3%). A retrospective analysis, using the data to estimate the sample size required for at least 90% power to detect a 15% difference between treatments in a two-way crossover study, established that 10 cats would be sufficient for plaque measurement by QLF, while assessment by the modified Logan and Boyce method required over 30 cats. QLF was determined to be a reliable, reproducible method for the assessment of plaque deposition in cats and requires fewer subjects for the detection of differences between treatment effects compared to the modified Logan and Boyce method.
Reversal of Hypermethylation and Reactivation of p16INK4a, RARβ, and MGMT Genes by Genistein and Other Isoflavones from Soy (2005)

These results indicate that genistein and related soy isoflavones reactivate methylation-silenced genes, partially through a direct inhibition of DNA methyltransferase, which may contribute to the chemopreventive activity of dietary isoflavones.
Prolonged serotonin toxicity with proserotonergic drugs in the intensive care unit (2009)

Serotonin toxicity secondary to drug therapy, interaction or overdose is an increasing phenomenon worldwide. A proportion of patients require admission to an intensive care unit, but the treatment needed is usually supportive and of short duration. Prolonged ICU admission to control ongoing or long-lasting serotonin toxicity has not been reported previously. We describe three patients with prolonged serotonin toxicity, lasting 12–18 days. Symptoms of toxicity were easily demonstrable in each and were refractory to currently recommended therapies. We review the pharmacological mechanisms that led to prolonged serotonin toxicity in these patients. Predictors for prolonged serotonin toxicity include involvement of irreversible monoamine oxidase inhibitors (MAOIs) or slowrelease preparations resistant to the effects of activated charcoal (eg, lithium). We also discuss the implications of prolonged toxicity for critical care management, to optimal patient outcomes
Synthesis, crystal structure, and magnetic resonance of dichloro- and diiodo(5-methyl-1-thia-5-azacyclooctane)palladium(II) (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis, crystal structure, and magnetic resonance of dichloro- and diiodo(5-methyl-1-thia-5-azacyclooctane)palladium(II)A. S. Hirschon, W. K. Musker, M. M. Olmstead, and J. L. DallasCite this: Inorg. Chem. 1981, 20, 6, 1702–1706Publication Date (Print):June 1, 1981Publication History Published online1 May 2002Published inissue 1 June 1981https://pubs.acs.org/doi/10.1021/ic50220a017https://doi.org/10.1021/ic50220a017research-articleACS PublicationsRequest reuse permissionsArticle Views31Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Improving intrusion detection radar (2002)

The first monostatic microwave intrusion detection sensor with range cutoff was introduced in 1984. This range cutoff circuit as used in the Model 375 and 385 has proven very effective in preventing nuisance alarms beyond a user-defined range. The Intrepid Digital Transceiver introduced in this paper builds upon this proven technology with the addition of a unique digital signal processing routine that measures range to the intruder. Intrepid Digital Transceiver alternately transmits pulses at two discrete frequencies within K-Band. When an intruder enters the detection zone, the Doppler response at each frequency is digitally recorded. The difference between the two frequencies is controlled so that the phase angle between the two Doppler responses can be used to determine the unambiguous range to the target. As a byproduct of the process targets approaching the transceiver can be distinguished from those moving away from the transceiver. Range information is used to enhance the signal processing. The amount of signal integration is increased with range in proportion to the width of the detection pattern so as to optimize the signal to noise ratio (SNR).
Mutational analysis of the major proline transporter (PrnB) ofAspergillus nidulans (2003)

PrnB, the l-proline transporter of Aspergillus nidulans, belongs to the Amino acid Polyamine Organocation (APC) transporter family conserved in prokaryotes and eukaryotes. In silico analysis and limited biochemical evidence suggest that APC transporters comprise 12 transmembrane segments (TMS) connected with relatively short hydrophilic loops (L). However, very little is known on the structure-function relationships in APC transporters. This work makes use of the A. nidulans PrnB transporter to address structure-function relationships by selecting, constructing and analysing several prnB mutations. In the sample, most isolated missense mutations affecting PrnB function map in the borders of cytoplasmic loops with transmembrane domains. These are I119N and G120W in L2-TMS3, F278V in L6-TMS7, NRT378NRTNRT and PY382PYPY in L8-TMS9 and T456N in L10-TMS11. A single mutation (G403E) causing, however, a very weak phenotype, maps in the borders of an extracellular loop (L9-TMS10). An important role of helix TMS6 for proline binding and transport is supported by mutations K245L and, especially, F248L that clearly affect PrnB uptake kinetics. The critical role of these residues in proline binding and transport is further shown by constructing and analysing isogenic strains expressing selected prnB alleles fused to the gene encoding the Green Fluorescent Protein (GFP). It is shown that, while some prnB mutations affect proper translocation of PrnB in the membrane, at least two mutants, K245E and F248L, exhibit physiological cellular expression of PrnB and, thus, the corresponding mutations can be classified as mutations directly affecting proline binding and/or transport. Finally, comparison of these results with analogous studies strengthens conclusions concerning amino acid residues critical for function in APC transporters.
Purification, characterization, and kinetic mechanism of S-adenosyl-L-methionine:macrocin O-methyltransferase from Streptomyces fradiae. (1988)

S-Adenosyl-L-methionine:macrocin O-methyltransferase catalyzes conversion of macrocin to tylosin, the terminal and main rate-limiting step of tylosin biosynthesis in Streptomyces fradiae. The O-methyltransferase was stabilized in vitro and purified to electrophoretic homogeneity. The purified enzyme had a molecular weight of 65,000 and consisted of two identical subunits of 32,000 with an isoelectric point of 4.5. The enzyme required Mg2+, Mn2+, or Co2+ for maximal activity and was catalytically optimal at pH 7.5-8.0 and 31 degrees C. The O-methyltransferase catalyzed the conversion of macrocin to tylosin at a stoichiometric ratio of 1:1. The enzyme also mediated conversion of lactenocin----desmycosin. The corresponding Vmax/Km ratios for the two analogous conversions were similar, and both enzymic conversions were susceptible to extensive competitive and noncompetitive inhibitions by macrolide metabolites. Steady-state kinetic studies for initial velocity, substrate analogue, and product inhibitions have allowed formulation of Ordered Bi Bi as the reaction mechanism for macrocin O-methyltransferase.
Untersuchungen zum pathogenen Mechanismus des Anti-Sarkolemm-Antikörpers bei primärer Cardiomyopathie (1974)

Über den Nachweis von spezifischen Antikörpern gegen Herzmuskulatur bzw. gegen Herzmuskelsarkolemm bei primären, idiopathischen Cardiomyopathien haben wir anläßlich der beiden letzten Tagungen der Gesellschaft für innere Medizin berichtet [1, 2]. Mit der Immunfluoreszenzmethode kann ein gegen Herzmuskelsarkolemm gerichtetes Immunglobulin in Gewebeschnitten nach Vorinkubation mit Patientenserum identifiziert und quantifiziert werden [4]. Dieses Immunglobulin ist nicht identisch mit dem nach rheumatischem Fieber nachgewiesenen, die antigenen Determinanten sind andere als die bei Streptokokkenerkrankungen beteiligten. Nur in ganz vereinzelten Fällen ließ sich ein Teil des Antikörpers aus Patientenseren durch ß-hämolytische Streptokokkenmembranen absorbieren [1]. Inzwischen haben wir insgesamt 68 Patienten mit einer primären Cardiomyopathie untersucht. 60 dieser 68 Patienten unseres Krankengutes hatten diesen Antikörper in ihrem Serum, gesunde Personen in keinem Fall [3]. Wie wir bereits berichtet haben, reagiert dieser Antikörper auch mit dem Sarkolemm des Schweineherzmuskels [2]. Dies wurde auf zweierlei Weise gezeigt: 1. Menschlicher Antisarkolemm-Antikörper wird im Gewebeschnitt von Schweineherzmuskulatur am Sarkolemm gebunden, allerdings mit 2- bis 3mal niedrigeren Titerstufen als in dem vom Humanherzmuskel, d. h. mit einer geringeren Affinität. 2. Mit steigenden Konzentrationen isolierter Membranvesikel aus Schweineherzmuskulatur wird der Antikörper gegen menschliches Herzmuskelsarkolemm aus dem Serum absorbiert.
Ridge augmentation planning, wound healing evaluation, and peri‐implant tissue phenotype assessment with ultrasonography: A case report (2023)

Why is this case new information? Novel high-resolution, chairside ultrasound was proposed to facilitate treatment planning and wound healing outcome assessment of ridge augmentation in clinical as well as research settings. What are the keys to successful use of this technology? Proper training in imaging acquisition and interpretation Adhere to high-level disinfection protocol Patient education and explanation What are the primary limitations to success in using this technology? Investment in this technology Learning curve in imaging acquisition and reading Insurance reimbursement strategy.
Synergistic molecular assembly of an aptamer and surfactant on gold nanoparticles for the colorimetric detection of trace levels of As3+ions in real samples (2018)

A facile and selective aptasensor was developed by the synergistic molecular assembly of the Ars-3 aptamer on AuNPs for the detection of As<sup>3+</sup>ions using CTAB as a binder.