gebhart/patrepeval huggingface dataset:
Pathophysiology and management of classic galactosemic primary ovarian insufficiency (2021)

Patients with the condition of classic galactosemia need to maintain a strict lifelong diet that excludes the sugar galactose. This is due to having mutations in enzymes that process galactose, resulting in the buildup of toxic metabolic by-products of the sugar. Young women with classic galactosemia often lose the function of their ovaries very early in life (termed 'primary ovarian insufficiency'), despite adherence to a galactose-restricted diet. This means that in addition to the consequences of the disease, these women also face infertility and the potential need for hormone replacement therapy. This article summarizes current strategies for managing the care of galactosemic girls and women and also what is known of how the condition leads to early primary ovarian insufficiency.
Achievement of High-Response Organic Field-Effect Transistor NO2 Sensor by Using the Synergistic Effect of ZnO/PMMA Hybrid Dielectric and CuPc/Pentacene Heterojunction (2016)

High-response organic field-effect transistor (OFET)-based NO₂ sensors were fabricated using the synergistic effect the synergistic effect of zinc oxide/poly(methyl methacrylate) (ZnO/PMMA) hybrid dielectric and CuPc/Pentacene heterojunction. Compared with the OFET sensors without synergistic effect, the fabricated OFET sensors showed a remarkable shift of saturation current, field-effect mobility and threshold voltage when exposed to various concentrations of NO₂ analyte. Moreover, after being stored in atmosphere for 30 days, the variation of saturation current increased more than 10 folds at 0.5 ppm NO₂. By analyzing the electrical characteristics, and the morphologies of organic semiconductor films of the OFET-based sensors, the performance enhancement was ascribed to the synergistic effect of the dielectric and organic semiconductor. The ZnO nanoparticles on PMMA dielectric surface decreased the grain size of pentacene formed on hybrid dielectric, facilitating the diffusion of CuPc molecules into the grain boundary of pentacene and the approach towards the conducting channel of OFET. Hence, NO₂ molecules could interact with CuPc and ZnO nanoparticles at the interface of dielectric and organic semiconductor. Our results provided a promising strategy for the design of high performance OFET-based NO₂ sensors in future electronic nose and environment monitoring.
Widely Tunable, Low Linewidth, and High Power Laser Source using an\n Electro-Optic Comb and Injection-Locked Slave Laser Array (2021)

We propose a simple approach to implement a tunable, high power and narrow\nlinewidth laser source based on a series of highly coherent tones from an\nelectro-optic frequency comb and a set of 3 DFB slave lasers. We experimentally\ndemonstrate approximately 1.25 THz (10 nm) of tuning within the C-Band centered\nat 192.9 THz (1555 nm). The output power is approximately 100 mW (20 dBm), with\na side band suppression ratio greater than 55 dB, and a linewidth below 400 Hz\nacross the full range of tunability. This approach is scalable and may be\nextended to cover a significantly broader optical spectral range.\n
Imaging mass spectrometry: Molecular microscopy for enabling a new age of discovery (2014)

The molecular expression from genomic, proteomic, and metabolomic processes ongoing in living cells is enormously complex, continuously challenging our ability to measure and understand their integrated totality. Important biological studies and advances in the understanding of the biochemistry and biology of living cells have most often been preceded by innovations in the technology used to probe cells, tissues, and animals that then facilitate new insightful observations. A great deal has been learned over the decades about individual enzymes and pathways from isolated samples and extracts from a wide variety of bacterial and animal sources and much progress has been made toward integrating these findings into a framework that describes the underlying biology. This reductionist approach has and will continue to be important; however, there exists a multitude of biological and clinical problems that will only be solved using a systems approach. The innovative and groundbreaking advances in genomic technology and the resultant information has led to a dramatic increase in our ability to measure and predict many of the molecular events involving both genotypic and proteomic processes. Today, multiplex molecular interactions and pathway connectivity can be understood through both direct measurement and predictive models in an impressive attempt to understand this totality at this point in our current knowledge. Although these efforts have greatly advanced our understanding of biological processes, the end game remains far off, especially since spatial and temporal dimensions are yet to be fully explored and integrated into this view of the intact integrated cell. Further, cells react with their environment so that even the same basic cell type will have altered expression depending on their local cellular environment. Although the overall task is daunting, investigators continue to make impressive breakthroughs in understanding this complexity and interdependence.
Effects of high altitude and water deprivation on arginine vasopressin release in men (2004)

High-altitude exposure changes the distribution of body water and electrolytes. Arginine vasopressin (AVP) may influence these alterations. The purpose of this study was to examine the effect of a 24-h water deprivation trial (WDT) on AVP release after differing altitude exposures. Seven healthy males (age 22 +/- 1 yr, height 176 +/- 2 cm, mass 75.3 +/- 1.8 kg) completed three WDTs: at sea level (SL), after acute altitude exposure (2 days) to 4,300 m (AA), and after prolonged altitude exposure (20 days) to 4,300 m (PA). Body mass, standing and supine blood pressures, plasma osmolality (Posm), and plasma AVP (PAVP) were measured at 0, 12, 16, and 24 h of each WDT. Urine volume was measured at each void throughout testing. Baseline Posm increased from SL to altitude (SL 291.7 +/- 0.8 mosmol/kgH2O, AA 299.6 +/- 2.2 mosmol/kgH2O, PA 302.3 +/- 1.5 mosmol/kgH2O, P < 0.05); however, baseline PAVP measurements were similar. Despite similar Posm values, the maximal PAVP response during the WDT (at 16 h) was greater at altitude than at SL (SL 1.7 +/- 0.5 pg/ml, AA 6.4 +/- 0.7 pg/ml, PA 8.7 +/- 0.9 pg/ml, P < 0.05). In conclusion, hypoxia appeared to alter AVP regulation by raising the osmotic threshold and increasing AVP responsiveness above that threshold.
Estudio teórico en interacciones débiles entre AUPC y superficies de cluster de oro (2018)

Tesis entregada a la Universidad de Chile en cumplimiento parcial de los Requisitos para optar al Grado de
Magister en Ciencias Quimicas.
FARM: Fault-aware resource management in NoC-based multiprocessor platforms (2011)

In this paper, we address the problem of run-time resource management in non-ideal multiprocessor platforms where communication happens via the Network-on-chip (NoCs) approach. More precisely, we propose a system-level fault-tolerant technique for application mapping which aims at optimizing the entire system performance and communication energy consumption, while considering the occurrence of permanent, transient, and intermittent faults in the system. As the main theoretical contribution, we address the problem of spare core placement and its impact on system fault-tolerance (FT) properties. Then, we investigate several metrics and provide insight into the fault-aware resource management process for such non-ideal multiprocessor platforms. Experimental results show that our proposed resource management technique is efficient and highly scalable and significant throughput improvements can be achieved compared to the existing solutions that do not consider failures in the system.
Theory of Photochemical and Radiochemical Lithographic Imaging Mechanisms (2016)

The interaction of organic and inorganic resist materials with photons of wavelengths between the x-ray region of the spectrum (0.2 and 2 nm) through the EUV (13.5 nm), DUV (193 and 248 nm), mid-UV (365 nm), and visible region of the spectrum (405, 436, and 700 nm), and with charged particles such as electrons have been exploited in lithographic imaging. This chapter attempts to describe the most important organic and inorganic photochemical and radiochemical imaging mechanisms that underlie these lithographies. Listed in Fig. 4.1 are the main photochemical and radiochemical imaging mechanisms that underlie advanced lithography. As discussed in Chapter 1 and shown in Fig. 1.1, resists are in two tones: negative and positive. For positive resists, the exposed part of the resist film is dissolved away during development, reproducing a positive image of the mask; in negative resists, the unexposed part of the resist is dissolved away during development, leaving the exposed part, and reproducing a negative image of the mask. The photochemical and radiochemical reactions that engender negative-tone resist imaging mechanisms include photo- and radiation-initiated polymerization, crosslinking, and polarity switching reactions such as condensation, pinacol rearrangement, esterification, and ligand exchange. Relative to the starting unexposed resist material, the negative-tone imaging mechanisms either lead to significant increase in molecular weight of the exposed resist material (as in polymerization and crosslinking imaging mechanisms), or polarity switching (as in condensation, pinacol rearrangement, esterification, and ligand exchange imaging mechanisms). In contrast, the photochemical and radiochemical reactions that engender positive-tone resist imaging mechanisms include photolysis and radiolysis, as well as radiation-induced main-chain scissioning, and depolymerization. The photolysis and radiolysis imaging mechanisms include dissolution inhibition, deprotection, and Claisen and photo-Fries rearrangement reactions. Relative to the starting unexposed resist material, the positive-tone imaging mechanisms lead to either a significant decrease in molecular weight (as in main-chain scissioning or depolymerization imaging mechanisms) or polarity switching (as in photolysis and radiolysis imaging mechanisms). Before we delve into the specifics of the above imaging mechanisms, we provide preliminary remarks on the photochemistry and photophysics associated with the interaction of radiation and resist materials.
Energy dissipation by fast electrons (1959)

The solution of these equations may be acceptable on the basis of the above-mentioned criteria.
Rabies virus matrix protein interplay with eIF3, new insights into rabies virus pathogenesis (2007)

Viral proteins are frequently multifunctional to accommodate the high density of information encoded in viral genomes. Matrix (M) protein of negative-stranded RNA viruses such as Rhabdoviridae is one such example. Its primary function is virus assembly/budding but it is also involved in the switch from viral transcription to replication and the concomitant down regulation of host gene expression. In this study we undertook a search for potential rabies virus (RV) M protein's cellular partners. In a yeast two-hybrid screen the eIF3h subunit was identified as an M-interacting cellular factor, and the interaction was validated by co-immunoprecipitation and surface plasmon resonance assays. Upon expression in mammalian cell cultures, RV M protein was localized in early small ribosomal subunit fractions. Further, M protein added in trans inhibited in vitro translation on mRNA encompassing classical (Kozak-like) 5'-UTRs. Interestingly, translation of hepatitis C virus IRES-containing mRNA, which recruits eIF3 via a different noncanonical mechanism, was unaffected. Together, the data suggest that, as a complement to its functions in virus assembly/budding and regulation of viral transcription, RV M protein plays a role in inhibiting translation in virus-infected cells through a protein-protein interaction with the cellular translation machinery.
Computation of induction logs in multiple-layer dipping formation (1989)

A technique to compute the response of an induction sonde in a dipping formation is presented. The effects of borehole and invasion are assumed to be negligible. The formation may have an arbitrary number of beds. The method developed is called the coefficient propagator method. It overcomes difficulties that usually occur in numerical integration due to exponential behavior of electromagnetic-wave propagation in dissipative media. The method is used to investigate the effects of dipping and laminated formations on induction logs.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Fluctuation-Free Electron Emission from Non-Formed Metal-Insulator-Metal (MIM) Cathodes Fabricated by Low Current Anodic Oxidation (1993)

Fluctuation-free electron emission is obtained from MIM (Al-Al 2 O 3 -Au) cathodes. The Al 2 O 3 layer is fabricated by anodic oxidation with a reduced electrolysis current density, i.e., a reduced oxidation rate. The slow oxidation process improves the insulating effect of the Al 2 O 3 layer, and enables the MIM cathodes to operate in the non-formed state. The fluctuation-free emission is reproducible when the diode voltage is cut off instantaneously. With a thin Al 2 O 3 layer, the diode voltage reguired for the cathode operation is reduced to values slightly above the work function of the top electrode.
A Hierarchical Deficit Round-Robin Scheduling Algorithm for a High Level of Fair Service (2007)

For the last several decades, many researches have been performed to distribute bandwidth fairly between sessions. In this problem, the most important challenge is to realize a scalable implementation and high fairness simultaneously. Here high fairness means that bandwidth is distributed fairly even in short time intervals. Unfortunately, existing scheduling algorithms either are lack of scalable implementation or can achieve low fairness. In this paper, we propose a scheduling algorithm that can achieve feasible fairness without losing scalability. The proposed algorithm is a Hierarchical Deficit Round-Robin (H-DRR). While H-DRR requires a constant time for implementation, the achievable fairness is similar to that of Packet-by-Packet Generalized Processor Sharing (PGPS) algorithm. PGPS has worse scalability since it uses a sorted-priority queue requiring O(logN) implementation complexity where N is the number of sessions.
REVIEWS GIDEANDRÉ: Le Roi Candaule. Édition critique présentée par POLLARDPATRICK. Tupin et Semons, Centre d'Études Gidiennes, 2000. li + 144 pp. Pb 120 F. (2001)

Journal Article REVIEWS Get access ANDRÉ GIDE: Le Roi Candaule. Édition critique présentée par PATRICK POLLARD. Tupin et Semons, Centre d'Études Gidiennes, 2000. li + 144 pp. Pb 120 F. DAVID H. WALKER DAVID H. WALKER UNIVERSITY OF SHEFFIELD Search for other works by this author on: Oxford Academic Google Scholar French Studies, Volume LV, Issue 4, October 2001, Page 565, https://doi.org/10.1093/fs/LV.4.565 Published: 01 October 2001
Nursing home resident assessment and case-mix classification: cross-national perspectives. (1992)

Two broadly applied systems in the United States, the National Resident Assessment Instrument/Minimum Data Set and the Resource Utilization Groups, have provided new insight into the quality, delivery, and financing of nursing home care. In this article, the authors describe research efforts in eight other nations to translate, validate, and use one or both systems to understand their own long-term care systems. This consortium of studies, using common instruments, provides potential cross-national analyses that capitalize on differences in practice patterns and system designs to address critical policy issues.
High Quality Anisotropic Tetrahedral Mesh Generation Via Ellipsoidal Bubble Packing. (2000)

This paper presents a new computational method for anisotropic tetrahedral meshing that (1) can control shapes of the elements by an arbitrary anisotropy function, and (2) can avoid ill-shaped elements induced from poorly distributed node locations. Our method creates a tetrahedral mesh in two steps. First our method obtains node locations through a physically based particle simulation, which we call &amp;apos;bubble packing. &amp;apos; Ellipsoidal bubbles are closely packed on the boundary and inside a geometric domain, and nodes are placed at the centers of the bubbles. Our method then connects the nodes to create a tet mesh by the advancing front method. Experimental results show that our method can create a high quality anisotropic tetrahedral mesh that conforms well to the input anisotropy.
Who Supported Obama in 2012? (2015)

We present a new solution to the ``ecological inference'' problem, of learning individual-level associations from aggregate data. This problem has a long history and has attracted much attention, debate, claims that it is unsolvable, and purported solutions. Unlike other ecological inference techniques, our method makes use of unlabeled individual-level data by embedding the distribution over these predictors into a vector in Hilbert space. Our approach relies on recent learning theory results for distribution regression, using kernel embeddings of distributions. Our novel approach to distribution regression exploits the connection between Gaussian process regression and kernel ridge regression, giving us a coherent, Bayesian approach to learning and inference and a convenient way to include prior information in the form of a spatial covariance function. Our approach is highly scalable as it relies on FastFood, a randomized explicit feature representation for kernel embeddings. We apply our approach to the challenging political science problem of modeling the voting behavior of demographic groups based on aggregate voting data. We consider the 2012 US Presidential election, and ask: what was the probability that members of various demographic groups supported Barack Obama, and how did this vary spatially across the country? Our results match standard survey-based exit polling data for the small number of states for which it is available, and serve to fill in the large gaps in this data, at a much higher degree of granularity.
Infrasound (1997)

This chapter contains sections titled: Introduction Sources of Infrasound Propagation Channels Instrumentation References
IS CHRONIC PROSTATITIS/CHRONIC PELVIC PAIN SYNDROME ASSOCIATED WITH CHRONIC RHINOSINUSITIS?: A STUDY BASED ON “NATIONAL INSTITUTE OF HEALTH- CHRONIC PROSTATITIS SYMPTOM INDEX” AND “SINONASAL OUTCOME TEST-22” QUESTIONNAIRES (2021)

Objectives/Aims: Prostatitis is a common entity that is seen in younger than 50 years old men in urology clinics. Subcategory of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) accounts for more than 90% of cases of prostatitis and heterogeneous symptoms cause negative impact on quality of life. Chronic rhinosinusitis (CRS) is a common inflammatory disease of the upper airways and results in a constellation of symptoms that have a significant negative effect on a patient’s quality of life, either. However, both of these entities may share an inflammatory background because of systemic inflammatory responses and endocrine effects of cytokines. In this study, we aimed to find if any symptomatic correlation between CP/CPPS and CRS that can be measurable with National Institute of Health- Chronic Prostatitis Symptom Index (NIH-CPSI) and Sinonasal Outcome Test-22 (SNOT-22) validated symptom scores. Methods: Patients from urology (n:113) and ear-nose-throat (ENT) clinics (n:104) are included in this study. They were questionned with NIH-CPSI and SNOT-22. Also, they were evaluated if there was a correlation between these scores and some parameters (e.g. age, marital status, smoking, masturbation frequency, concomitant inflammatory diseases). Results: As our main result we found out a low-moderate correlation between NIH-CPSI and SNOT-22 scores (r:0.370 for urology, r: 0.466 for ENT patients). Conclusions: In this study we found that, CP/CPPS and CRS have a low correlated relationship symptomatically. We suggest that with further studies and additional data, CP/CPPS and CRS symptom relation might have been connected to a possible main root.
A Fault Detection Index Using Principal Component Analysis And Mahalanobis Distance (2015)

This paper proposes a novel index to detect a sensor fault based on Principal Component Analysis (PCA) method. The main idea behind this index is to evaluate similarity between Principal Components PCs that represent a normal behavior of a system and a new PCs that represent current function. This index is evaluated on a Chemical Reactor (CSTR) and the results are satisfactory.
Purine Salvage Pathways among Borrelia Species (2007)

Genome sequencing projects on two relapsing fever spirochetes, Borrelia hermsii and Borrelia turicatae, revealed differences in genes involved in purine metabolism and salvage compared to those in the Lyme disease spirochete Borrelia burgdorferi. The relapsing fever spirochetes contained six open reading frames that are absent from the B. burgdorferi genome. These genes included those for hypoxanthine-guanine phosphoribosyltransferase (hpt), adenylosuccinate synthase (purA), adenylosuccinate lyase (purB), auxiliary protein (nrdI), the ribonucleotide-diphosphate reductase alpha subunit (nrdE), and the ribonucleotide-diphosphate reductase beta subunit (nrdF). Southern blot assays with multiple Borrelia species and isolates confirmed the presence of these genes in the relapsing fever group of spirochetes but not in B. burgdorferi and related species. TaqMan real-time reverse transcription-PCR demonstrated that the chromosomal genes (hpt, purA, and purB) were transcribed in vitro and in mice. Phosphoribosyltransferase assays revealed that, in general, B. hermsii exhibited significantly higher activity than did the B. burgdorferi cell lysate, and enzymatic activity was observed with adenine, hypoxanthine, and guanine as substrates. B. burgdorferi showed low but detectable phosphoribosyltransferase activity with hypoxanthine even though the genome lacks a discernible ortholog to the hpt gene in the relapsing fever spirochetes. B. hermsii incorporated radiolabeled hypoxanthine into RNA and DNA to a much greater extent than did B. burgdorferi. This complete pathway for purine salvage in the relapsing fever spirochetes may contribute, in part, to these spirochetes achieving high cell densities in blood.
Culex Mosquitoes (Diptera: Culicidae) Egg Laying in Traps Loaded With Bacillus thuringiensis Variety israelensis and Baited With Skatole (2010)

The Southern house mosquito, Culex quinquefasciatus, is an important human health pest as a vector of several pathogens, including agents of lymphatic filariasis and arboviruses like West Nile virus. We conducted preliminary experiments in Recife, Brazil, to explore applications of Culex oviposition attractants in combination with Bacillus thuringiensis variety israelensis (Bti) in an attract-and-kill approach. Simple, cost-effective oviposition traps, BR-OVT, loaded with Bti and baited with or without attractant, were deployed in 10 homes for 30 d in 2 consecutive yr. Significantly higher numbers of egg rafts were deposited in traps baited with skatole or infusion than the control water traps. In the first year, 2006, significantly higher numbers of eggs were deposited in infusion-baited traps, particularly in the first 15 d of the experiment, than in skatole traps, but in the following year no significant difference was observed between synthetic and natural attractants. The tests strongly demonstrate that skatole or infusion can be used to enhance the number of egg rafts deposited on Bti-treated oviposition traps.