gebhart/patrepeval huggingface dataset:
Flexible megahertz organic transistors and the critical role of the device geometry on their dynamic performance (2021)

The development of organic thin-film transistors (TFTs) for high-frequency applications requires a detailed understanding of the intrinsic and extrinsic factors that influence their dynamic performance. This includes a wide range of properties, such as the device architecture, the contact resistance, parasitic capacitances, and intentional or unintentional asymmetries of the gate-to-contact overlaps. Here, we present a comprehensive analysis of the dynamic characteristics of the highest-performing flexible organic TFTs reported to date. For this purpose, we have developed the first compact model that provides a complete and accurate closed-form description of the frequency-dependent small-signal gain of organic field-effect transistors. The model properly accounts for all relevant secondary effects, such as the contact resistance, fringe capacitances, the subthreshold regime, charge traps, and non-quasistatic effects. We have analyzed the frequency behavior of low-voltage organic transistors fabricated in both coplanar and staggered device architectures on flexible plastic substrates. We show through S-parameter measurements that coplanar transistors yield more ideal small-signal characteristics with only a weak dependence on the overlap asymmetry. In contrast, the high-frequency behavior of staggered transistors suffers from a more pronounced dependence on the asymmetry. Using our advanced compact model, we elucidate the factors influencing the frequency-dependent small-signal gain and find that even though coplanar transistors have larger capacitances than staggered transistors, they benefit from substantially larger transconductances, which is the main reason for their superior dynamic performance.
Simposio 9: Higado y diabetes: mas alla de la glucemia (2020)

Simposio 9: El compromiso hepático en diabetes: más allá del hígadoHígado y diabetes: más allá de la glucemiaLa enfermedad de hígado graso no alcohólico (NAFLD) representa la respuesta hepática al insulto de un metabolismo sistémico alterado. En América del Sur un 25% de los sujetos “sanos” tiene NAFLD, principalmente esteatosis simple (ES), y de éstos un 20% puede progresar a esteato-hepatitis no alcohólica (NASH), que implica la presencia de balonización hepatocitaria e inflamación. Más importante aún es que un 20% de los pacientes con NASH puede progresar a fibrosis, incluso a la cirrosis. Se ha considerado por años a la ES como una enfermedad “benigna”, aunque dicho paradigma se está poniendo en duda a partir del seguimiento de pacientes con biopsias seriadas en los que se vio que hasta un 25% de los pacientes con ES progresó a fibrosis. ¿Por qué es importante identificar a pacientes con fibrosis? Porque ésta se relaciona directamente con mayor mortalidad.
New Transfusion Strategies: Red Cell Substitutes (1999)

Red cell substitutes are solutions that can potentially be used in emergencies or during surgery when rapid expansion of the blood volume with an oxygen carrier is needed. The three main types of products in development are based on cell-free hemoglobin, perfluorocarbon emulsions, or liposome-encapsulated hemoglobin. None is currently approved for clinical use, but several are in advanced clinical trials. Outside the red blood cell, hemoglobin is subject to degradation and heme loss. It readily diffuses in the plasma space and effectively scavenges nitric oxide. These properties must be understood and controlled if hemoglobin-based products are to fulfill their promise. The development of red cell substitutes affords us a deeper insight into how oxygen is delivered to tissues in the microcirculation and how blood-flow distribution is regulated within and between organs. As red cell substitutes become available to clinicians and scientists, clinical applications are expected to expand.
Two-photon sensitive photolabile protecting groups: From molecular engineering to nanostructuration (2014)

Molecular engineering of highly efficient two-photon sensitive photo-labile protecting groups (cages) for neuroscience will be presented as well as nano-structuration of such molecular systems. Application of caged glutamate in brain sciences will be emphasized.
ChemInform Abstract: Application of Elementoorganic Compounds of 15th and 16th Groups in Organic Synthesis. Part 82. An Efficient SbCl3‐Metal System for Allylation, Reduction and Acetalization of Aldehydes. (1990)

Abstract A novel and highly efficient method of allylation, reduction and acetalization of aldehydes is described, which works under very mild conditions.
A Review on Device-Free Passive Indoor Positioning Methods (2014)

There is an increasing need for unobtrusive positioning systems in smart homes and assisted living environments. This review presents the main technologies used for device-free passive indoor positioning, including pressure sensors, thermal infrared sensors, sound source localization, ultrasound, radio frequency, infrastructure-mediated sensing and electric-field-based methods. In addition, it compares the advantages and disadvantages of a range of positioning systems to help identify the most suitable positioning technology for specific cases.
Integrating Producibility and Product Performance Tools Within a Web-Service Environment (2003)

This paper describes the integration of a producibility and product performance tool in a web service environment. First, we provide a background on web services and a review of product development environments that utilize a service-based architecture. Next, the paper describes the implementation of two services—a process capability database coupled with an aircraft engine fuel nozzle performance model. Discussions close addressing the challenges faced in the current software services development environment.
RLE (Research Laboratory of Electronics) Progress Report Number 129. Report for January-December 1986 (1987)

This is report No. 129 in a series of progress reports issued by the Research Laboratory of Electronics at MIT. The report covers the period January 1 through December 31, 1986 and contains a statement of research objectives, summary of research efforts and lists of funding sources and project staff for each research group within RLE. There are indexes of funding sources and research project staff, and extensive bibliography, and a listing of RLE personnel at the back of the book.
Structural basis for the formation of soy protein nanofibrils (2019)

Amyloid-like protein nanofibrils (PNFs) can assemble from a range of different proteins including disease-associated proteins, functional amyloid proteins and several proteins for which the PNFs are neither related to disease nor function. We here examined the core building blocks of PNFs formed by soy proteins. Fibril formation at pH 2 and 90 °C is coupled to peptide hydrolysis which allows isolation of the PNF-forming peptides and identification of them by mass spectrometry. We found five peptides that constitute the main building blocks in soy PNFs, three of them from the protein β-conglycinin and two from the protein glycinin. The abilities of these peptides to form PNFs were addressed by amyloid prediction software and by PNF formation of the corresponding synthetic peptides. Analysis of the structural context in the native soy proteins revealed two structural motifs for the PNF-forming peptides: (i) so-called β-arches and (ii) helical segments involved in quaternary structure contacts. However, the results suggest that neither the native structural motifs nor the protein of origin defines the morphology of the PNFs formed from soy protein isolate.
Extended architecture and Hypervisor performance (1973)

This paper is a brief summary of the impact that architecture extensions to hardware and software have upon the design and performance of software Hypervisors that are intended to provide the extended function in a virtual machine environment.
Recurrent Feature Reasoning for Image Inpainting (2020)

Existing inpainting methods have achieved promising performance for recovering regular or small image defects. However, filling in large continuous holes remains difficult due to the lack of constraints for the hole center. In this paper, we devise a Recurrent Feature Reasoning (RFR) network which is mainly constructed by a plug-and-play Recurrent Feature Reasoning module and a Knowledge Consistent Attention (KCA) module. Analogous to how humans solve puzzles (i.e., first solve the easier parts and then use the results as additional information to solve difficult parts), the RFR module recurrently infers the hole boundaries of the convolutional feature maps and then uses them as clues for further inference. The module progressively strengthens the constraints for the hole center and the results become explicit. To capture information from distant places in the feature map for RFR, we further develop KCA and incorporate it in RFR. Empirically, we first compare the proposed RFR-Net with existing backbones, demonstrating that RFR-Net is more efficient (e.g., a 4\% SSIM improvement for the same model size). We then place the network in the context of the current state-of-the-art, where it exhibits improved performance. The corresponding source code is available at: https://github.com/jingyuanli001/RFR-Inpainting
The z990 first error data capture concept (2004)

Superior availability is one of the outstanding features of modern zSeries® machines, among the most highly rated of any existing computer platforms in this reqard. Many features contribute to this characteristic, some in hardware, some in software. This paper describes the first error data capture (FEDC) concept in the zSeries 990. The concept is used for both zSeries integration efficiency and its ability to gain field data for problem determination in the user environment. FEDC is not a single function, but part of all internal software (firmware) in the z990. This paper explains the overall concept and implementation details of the various internal functional layers (subsystems).
Monomethylparaffins in <i>n</i>-Paraffins Adducted from Petroleum Fractions (1975)

The capillary gas-liquid chromatographic methods and/or gas chromatographic-mass spectrographic methods had been tested to determine the monomethylparaffins in n-paraffin fractions separated from petroleum distillates by means of urea. 27 monomethylparaffins, included all isomers of monomethyldecane, monomethylundecane and monomethyldodecane, were identified or estimated in n-paraffin fraction separated from middle distillates, and these monomethylparaffins amounted to 95wt% of all components other than n-paraffins. In the C18 fraction of n-paraffins separated from heavy distillates, all isomers of monomethylheptadecane were detected and in the C20 fraction all isomers of monomethylnonadecane were also detected. From these results it was estimated that all sorts of isomers of monomethylparaffins were present in n-paraffin fractions separated from petroleum fractions by means of urea and the amount of those monomethylparaffins occupied a large portion of components other than n-paraffins all over the boiling range.
Occurrence of maximum T c at an optimal carrier concentration in superconducting bismuth and thallium cuprates (1990)

The superconducting transition temperatures in Bi2Ca1−xLnxSr2Cu2O8+δ, TlCa1−xLnxSr2Cu2O6+δ, and Tl0.8Ca1−xLnxBa2Cu23O6+δ (Ln=Y or rare earth) vary with composition and show a maximum at a specific value of x or δ. This observation suggests that an optimal carrier concentration is required to attain maximum Tc in such cuprates which seem to be two-band systems.
Characterizing photon emission from a quantum dot excited by long above-band pulses (2023)

We experimentally investigate the quality of single photons produced with long-pulse above-band excitation of a quantum dot embedded in a semiconductor nanowire and model the results via rate equations and Markov-chains.
Applications of photoluminescence excitation spectroscopy to the study of indium gallium phosphide alloys (1970)

Photoluminescence excitation spectroscopy of (InGaP) has been used to analyse alloy inhomogeneities and variations in impurity concentration which arise owing to growth by liquid phase epitaxy. The method has experimental advantages over absorption techniques for rapid assessment of III-V semiconductors. The effect of direct transitions in indirect alloys has been observed, and is consistent with previous estimates of the composition corresponding to the crossover from direct gap to indirect gap alloys
Hyperphosphorylation of the N-terminal Domain of Cdc25 Regulates Activity toward Cyclin B1/Cdc2 But Not Cyclin A/Cdk2 (1997)

Cdc25 regulates entry into mitosis by regulating the activation of cyclin B/cdc2. In humans, at least two cdc25 isoforms have roles in controlling the G2/M transition. Here we show, using bacterially expressed recombinant proteins, that two cdc25B splice variants, cdc25B2 and cdc25B3, are capable of activating cyclin A/cdk2 and cyclin B/cdc2, but that mitotic hyperphosphorylation of these proteins increases their activity toward only cyclin B1/cdc2. Cdc25C has only very low activity in its unphosphorylated form, and following hyperphosphorylation it will efficiently catalyze the activation of only cyclin B/cdc2. This was reflected by the in vivo activity of the immunoprecipitated cdc25B and cdc25C from interphase and mitotic HeLa cells. The increased activity of the hyperphosphorylated cdc25s toward cyclin B1/cdc2 was in large part due to increased binding of this substrate. The substrate specificity, activities, and timing of the hyperphosphorylation of cdc25B and cdc25C during G2 and M suggest that these two mitotic cdc25 isoforms are activated by different kinases and perform different functions during progression through G2 into mitosis.
The percutaneous coronary angioplasty gets better, but the surgical coronary artery bypass does not stay behind (2022)

Coronary artery bypass grafting remains one of the most frequently performed cardiac operations, with well-established prognostic benefits in patients with multivessel coronary artery disease and left main disease. Despite an increasingly higher patients' risk profile, the results of this procedure have significantly improved over time, with an evident and striking decrease in operative mortality and peri-operative complications. A fair amount of technical and technological refinements has further improved the short- and long-term results of coronary artery bypass surgery. The improvements in the beating heart coronary surgery and aortic 'no-touch' technique, in the appropriate use of conduits (bilateral internal mammary artery, radial artery, and composite conduits configuration), and in the optimization of venous grafts' patency are reviewed.
Comparison of self-heating effects in bulk-silicon and SOI high-voltage devices (2002)

A study of the self-heating effect in SOI and bulk-Si power devices which were subjected to large transient power overloads is described. The time-dependent temperature rise and decay was measured and compared in the two device types by relating the transient on-resistance of the device to its temperature. The temperature rise in SOI devices is shown to be more rapid than in bulk-Si devices in the initial stage of the power pulse. With extended pulse duration the difference between the temperature rise in SOI and bulk-Si devices converges to a constant value which is proportional to the thickness of the buried oxide. This difference is relatively small in comparison to the overall temperature rise.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Complex role of HIF in cancer: the known, the unknown, and the unexpected (2014)

Tumor hypoxia has long been recognized as a driving force of malignant progression and therapeutic resistance. The discovery of hypoxia-inducible transcription factors (HIFs) has greatly advanced our understanding of how cancer cells cope with hypoxic stress by maintaining bioenergetics through the stimulation of glycolysis. Until recently, however, it remained perplexing why proliferative cancer cells opt for aerobic glycolysis, an energy-inefficient process of glucose metabolism. Furthermore, the role of HIF in cancer has also become complex. In this review, we highlight recent groundbreaking findings in cancer metabolism, put forward plausible explanations to the complex role of HIF, and underscore remaining issues in cancer biology.
Unsaturated carbohydrates. Part XIV. The isomerisation of hex-2-enopyranosylpurine nucleoside derivatives (1971)

In corroboration of previous reports, tri-O-acetyl-D-glucal has been found to give 4′,6′-di-O-acetyl-2′,3′-dideoxy-D-erythro-hex-2-enopyranosyl nucleosides on condensation with substituted purines. These products, however, are now shown to be formed under kinetic control; on heating with acids or in inert high-boiling solvents they rearrange to afford isomers with 3-deoxyglycal structures having the bases attached at C-3.
Clinical evaluation of neutron beam therapy. Current results and prospects, 1983 (1985)

Some 9000 patients throughout the world have been treated by some form of neutron beam therapy. These include patients with advanced nonresectable tumors in many different sites treated with a variety of neutron beam generators varying widely in beam energy. Protocols were largely nonrandomized and included both mixed beam studies (neutrons + photons) and neutrons alone in varying doses. In spite of wide variation in equipment, treatment technique, and philosophy, some consistent trends have been identified: (1) in general, the neutron results have been at least as good as those of the photon controls measured in terms of local control, although the incidence of significant side effects have been higher; (2) in none of the randomized studies conducted so far, largely comprising epidermoid carcinomas of the head and neck, has a clear survival advantage for neutrons over photon controls been demonstrated at a statistically significant level; (3) results with mixed beam studies have been uniformly equivocal, with marginally significant differences in favor of the experimental groups compared with the photon controls; (4) adenocarcinomas of the gastrointestinal tract (GI) tract, including tumors of the salivary gland, pancreas, stomach, and bowel, appear to be responsive to high linear energy transfer (LET) radiation; (5) nonepidermoid, radioresistant tumors (sarcoma of bone and soft tissue and melanoma) yield a consistantly high local control rate, with neutron irradiation strikingly superior to those reported with photon therapy; and (6) in the central nervous system, both normal tissues and tumors appear to be exceptionally sensitive to neutron irradiation, therapeutic ratios are small, and the prospect of cure remains remote. It is concluded that neutrons are efficacious for certain specific tumor types, but that essentially new study designs, based on nonrandomized matched case comparisons, will be required to prove the merit of the new modality.
Synthesis and Reactivity of Functionalized Binary and Ternary Thiometallate Complexes [(RT)4S6], [(RSn)3S4]2−, [(RT)2(CuPPh3)6S6], and [(RSn)6(OMe)6Cu2S6]4− (R=C2H4COOH, CMe2CH2COMe; T=Ge, Sn) (2009)

A series of compounds comprising functionalized thiometallate cages [(RT)4S6] (R terminated by COO(H) or COR groups), based on adamantane (T=Ge) or double-decker (T=Sn) type structures or [(RSn)3S4]2- anionic defect heterocubanes were synthesized and their reactions with 1) transition-metal compounds and 2) hydrazine derivatives were explored. Hence it was possible to generate functionalized ternary CuSnS or CuGeS clusters and to transfer COR ligands into CR(N-NH2) or CR(N-NHPh) terminal groups, respectively. The report provides the proof-of-principle for a directed functionalization and derivatization of chalcogenidometallate cages with respect to the formation of chalcogenidometallate-organic hybrid compounds containing M/E semiconductor nodes, as an alternative to the so far most prominent M/O combination in metal-organic frameworks. DFT investigations deliver further insight in the peculiarities of Ge/S versus Sn/S precursors and their products.
5.4.4 Optimizing Distributed Software Architectures for Ground Based Weapon Systems (2002)

Abstract Modern ground based weapon systems depend heavily upon electronics and software for correct and safe operations. Many of these ground based weapon systems exhibit behaviors from very different domains: automobiles (e.g. engines and transmissions), aircraft avionics systems (e.g. sophisticated sensors and advanced situational awareness), and hard real‐time industrial controls (e.g. weapon loading equipment). This paper describes the fundamental approach to Crusader's software architecture and through specific examples, demonstrates that the Crusader software architecture is highly adaptable, provides a firm technical foundation for evolutionary growth, and is capable of supporting a family of ground based weapon systems.
Dispersal ofRhyzopertha dominica(Coleoptera: Bostrichidae) in Different Habitats (2010)

The lesser grain borer, Rhyzopertha dominica (F.) (Coleoptera: Bostrichidae), a serious pest of stored cereal grains, is widely distributed and has been collected in different habitats in North America, such as those from agricultural and nonagricultural settings. Our objective was to study the dispersal distances and direction of dispersal by R. dominica after external marking using fluorescent powder, releasing marked beetles, and recapturing adults using pheromone traps in distinctively different ecological habitats, wooded sites and open grasslands, for 2 consecutive yr. The recapture rate of marked beetles ranged from 6 to 26% in both sites and was generally higher in the wooded site than the open field site for both years. There was a significant difference in dispersal distances between wooded and open sites. Mean dispersal distances in the wooded site ranged from 337 to 375 m, whereas in the open site, they varied from 261 to 333 m. Trap captures for both marked and feral beetles were related to the ambient temperature such that increase in trap captures occurred with increasing temperature. Significant differences were observed for directional movement of R. dominica in both sites and indicated that most beetles dispersed in the northwest direction. Correlation analyses showed that the relationship between numbers of marked-released-recaptured beetles significantly decreased with increasing trap distances. Understanding dispersal distances and directions provide insight to flight behavior of R. dominica and to the relationship between ecologically diverse breeding habitats. Knowledge of R. dominica habitat ecology outside of grain storage facilities may be useful in designing suitable management tactics to minimize the onset of infestations in grain storages.
Use of Human Intestinal Enteroids to Detect  Human Norovirus Infectivity (2019)

Tools to detect human norovirus infectivity have been lacking. Using human intestinal enteroid cultures inoculated with GII.Pe-GII.4 Sydney-infected fecal samples, we determined that a real-time reverse transcription PCR cycle threshold cutoff of 30 may indicate infectious norovirus. This finding could be used to help guide infection control.
ChemInform Abstract: Reversible Hydrogen Storage in Ti—Zr‐Codoped NaAlH4 under Realistic Operation Conditions. (2010)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.