gebhart/patrepeval huggingface dataset:
Heuristic Search Strategy for Transforming Microstructural Patterns to Optimal Copolymerization Recipes (2018)

Abstract Manipulation and optimization of copolymer microstructure for tailoring final properties is of great importance in macromolecular science and engineering. Uncovering the complexities of the interrelationships between copolymerization recipe and copolymer microstructure (a challenging field of study in its own right) is a multiobjective optimization problem, which has attracted a lot of attention in the last 10–15 years. In the present study, a powerful optimizer is developed based on the Non‐dominated Sorting Genetic Algorithm (NSGA‐II) for transforming desired microstructural copolymerization profiles, including molecular weight distribution and chemical composition distribution, back to optimal copolymerization recipes and operating conditions. The optimizer developed has the beneficial features of robust machine learning and multiobjective optimization based upon heuristic search strategies. The metallocene‐catalyzed ethylene/α‐olefin copolymerization is selected as a sufficiently complex system to challenge the proposed optimization tool. The developed computer code is used to explore copolymerization recipes (polymerization temperature and concentrations of ethylene, 1butene, cocatalyst, and hydrogen) needed to synthesize copolymers having desired microstructural features. Based on the results obtained, it is now possible to produce various grades or tailor‐make the copolymer structure by suggesting the “best” copolymerization recipe/conditions as reliably as possible.
Study on the saccharification technology of beer brewing by using extruded rice and enzyme agent (2005)

In the paper the relationship between the extraction obtaining ratio of mash and the parameters of the saccharification process of beer brewing by using extruded rice and enzyme agent was studied, in order to get the high extraction obtaining ratio of mash and provide theoretical grounds for applying to manufacture practice in the future. The main saccharification indexes of extruded and non-extruded beer adjuncts were basically same and very well. The extraction obtaining ratio of mash of extruded beer adjuncts was 4.22 more than that of traditional cooking non-extruded beer adjunct.
Computational pseudorandomness, the wormhole growth paradox, and\n constraints on the AdS/CFT duality (2019)

A fundamental issue in the AdS/CFT correspondence is the wormhole growth\nparadox. Susskind's conjectured resolution of the paradox was to equate the\nvolume of the wormhole with the circuit complexity of its dual quantum state in\nthe CFT. We study the ramifications of this conjecture from a\ncomplexity-theoretic perspective. Specifically we give evidence for the\nexistence of computationally pseudorandom states in the CFT, and argue that\nwormhole volume is measureable in a non-physical but computational sense, by\namalgamating the experiences of multiple observers in the wormhole. In other\nwords the conjecture equates a quantity which is difficult to compute with one\nwhich is easy to compute. The pseudorandomness argument further implies that\nthis is a necessary feature of any resolution of the wormhole growth paradox,\nnot just of Susskind's Complexity=Volume conjecture. As a corollary we conclude\nthat either the AdS/CFT dictionary map must be exponentially complex, or the\nquantum Extended Church-Turing thesis must be false in quantum gravity.\n
비탄력 발목 테이핑이 기능적 발목 불안정성을 가진 농구선수의 관절가동범위, 고유수용성 감각 및 기능적 수행능력에 미치는 영향 (2012)

본 연구의 목적용 비탄력 발목 테이핑이 남자 농구선수의 경기 중 관철기통범위, 고유수용성 감각, 그리고 기능적 수행능력에 미치는 영향을 규명하는 것이었다. 기능적 발목 불안정성을 가진 남자 대학 농구선수 10명이 연구대상으로 본 연구에 참여하였으며, 이들은 테이핑 처지와 통제 처치에 반복적으로 참여하였다. 각 처치를 적용하여 l쿼터 10분으로 구성된 총 4쿼터의 모의 농구경기를 실시하도록 하였고, 각 시점에서 관절가통범위, 고유수용성 감각, 그리고 기능적 수행능력을 측정하여 처치 간에, 그리고 시점 간에 비교·분석하였다. 본 연구에서 얻은 결과를 요약하여 제시하면 다음과 같다. 1) 테이핑 처치 시 관절가동범위가 배측굴곡-저측굴곡 각도와 내번-외번 각도 모두 통제 저지에 비하여 유의하게 낮게 나타났다. 또한 테이핑 처치 시 관절가동범위는 시점이 지날수록 유의하게 증가된 반연, 통제 처치 시에는 시점 간에 유의한 차이가 나타나지 않았다. 2) 테이핑 처치 시 고유수용성 감각이 모든 방향에서 통제 처치에 비하여 높게 나타났다. 테이명 처치와 통제 저지 내에서 시점 간에는 유의한 차이가 나타나지 않았다. 3) 테이핑 처치 시 기능적 수행능력이 팔자형 호프 테스트와 정사각형 호프 테스트 모두 통제 처지에 비하여 유의하게 우수한 것으로 나타났다. 두 처치 시 모두 시접이 지닐수록 저조해지는 양상을 보였다. 이상의 결과를 종합해 보면, 비탄력 테이평은 기능적 발목 불안정성을 가진 농구선수의 관절가동범위, 고유수용성 감각, 그리고 기능적 수행능력의 향상에 효과적인 것으로 결론지을 수 있으며, 그 효과가 40분의 농구와 유사한 운동 전반에 걸쳐 지속되고 있는 것을 확인할 수 있었다.
葡萄硝子室土壤の化学的組成,とくに可溶性塩類の異常集積に関する研究 (第1報) 葡萄硝子室土壤の化学的組成の特徴について (1959)

There are several problems with respect to soil managements of glasshouse vineyard. It has been recognized that the vine cultivated in glasshouse grows weak very faster than that cultivated in field. It may be supposed that the nature of glasshouse soil should affect directly or indirectly on the growth of vine in glasshouse. The purpose of this investigation is to study the effects of soil managements on the chemical composition of glasshouse vine soils and to compare the chemical properties of these with normal arable soils in connection with the growth of vine. Surface soils (0-10 cm) and subsoils (30-40 cm) used were taken from 67 glasshouse distributed in Tsudaka-cho, Okayama Prefecture. Electrical conductivity of saturated soil extracts, pH, humus and nitrate nitrogen were determined and soluble salts of 1 : 5 soil extracts were analysed with some typical soils. The results obtained may be summarized as follows: 1) It was found that the salinity of glasshouse soils, expressed as electrical conductivity was generally high as compared to normal arable soils, ranging from 1.15 to 22.81 millimhos/cm with the surface soils and from 0.70 to 7.96 millimhos/cm with the subsoils. Of all the soil samples examined, 63% of surface soils and 22% of subsoils showed the conductivity more than 4 millimhos/cm. 2) The normally dominant salts in the extracts was calcium sulfate but nitrate, chloride and bicarbonate were relatively high also. 3) The nitrate nitrogen content was also generally high, ranging from 11 to 815 p.p.m. in surface soils and from 3 to 236 p.p.m. in subsoils. Of all the soil samples examined, 48% of surface soils and 15% of subsoils contained nitrate nitrogen more than 100 p.p.m. 4) The reaction of most soils was found neutral to slightly alkaline, in pH range of 5.8 to 7.6 with surface soils and 5.1 to 7.6 with subsoils. 5) The content of humus was generally low, ranging from 0.62 to 4.36% in surface soils and from 0.32 to 2.52% in subsoils. As it had been expected, the nature of glasshouse soil was found to have more or less the characteristics of the soils formed under the semiarid climatic conditions. On the basis of these findings, it can be concluded that the injury of vine in old glasshouse is due partly to the accumulation of soluble salts, especially sulfate and nitrate in the soils. We found that the conductivity method provided reliable estimate of salinity of soils in relation to the adverse effects of soluble salts on the plant and a modification of the Spurway technique, which had been developed by authors could be used as the rapid method for routine nitrate determination.
Incentivizing crowdsourcing for radio environment mapping with statistical interpolation (2015)

White Space Networking crucially relies on the active monitoring of spectrum usage (to identify white space opportunities) in both space and time. One way to achieve this is wide-area deployment of spectrum sensors to gather spatio-temporal spectrum data, and use them to construct better Radio Environment Maps (REMs) via suitable statistical interpolation techniques (i.e., Kriging). Cost of such large-scale sensor deployment can be reduced via crowdsourcing, i.e., outsourcing the sensing task to mobile users equipped with sensorized high-end client devices (e.g., tablets or smartphones), and success of such crowdsourced sensing presumes some incentive mechanisms to attract user participation. In this work, we present an incentivized crowdsourcing system architecture that (periodically) acquires spectrum data from users, so as to optimize the resulting radio environment map (i.e., minimizing the average prediction-error variance) for a given data acquisition budget. First, we introduce an auction-based incentive mechanism that is computationally efficient, individually rational and truthful, and prove that the total payment of the proposed mechanism is a monotonically increasing function of the cardinality of the winner set. Then we propose a budget-feasible version and through extensive simulations, we evaluate the performance of proposed mechanisms for comparison to a baseline to demonstrate its significantly superior performance in crowdsourced radio mapping.
A Ras-GTPase-Activating Protein SH3-Domain-Binding Protein (1996)

We report the purification of a Ras-GTPase-activating protein (GAP)-binding protein, G3BP, a ubiquitously expressed cytosolic 68-kDa protein that coimmunoprecipitates with GAP. G3BP physically associates with the SH3 domain of GAP, which previously had been shown to be essential for Ras signaling. The G3BP cDNA revealed that G3BP is a novel 466-amino-acid protein that shares several features with heterogeneous nuclear RNA-binding proteins, including ribonucleoprotein (RNP) motifs RNP1 and RNP2, an RG-rich domain, and acidic sequences. Recombinant G3BP binds effectively to the GAP SH3 domain G3BP coimmunoprecipitates with GAP only when cells are in a proliferating state, suggesting a recruitment of a GAP-G3BP complex when Ras is in its activated conformation.
Compositional Phase Transition of Amorphous AlON (2009)

We have clarified the compositional dependence of the thermal stabilities and chemical structures of aluminum oxynitride (AlON) films. Thermally induced changes in composition and structure of AlON with various compositional ratio (R=N/(N+O)) have been investigated. Although AlON films show amorphous phase in the wide range of R, we find that AlON has two chemically different phases with different thermal stability, which are separated at critical nitrogen composition of R=0.4. Rutherford back scattering measurement and infrared spectroscopy indicate that AlON with R&lt;0.4 shows structural phase transition and nitrogen desorption occurred by thermal annealing. In contrast, AlON with R&gt;0.4 is thermally stable amorphous phase. We propose a model of bonding structure which explains the thermal stability of AlON.
Modellazione 3D del trasporto di particelle colloidali per la nanoremediation di acquiferi contaminati (2018)

Modellazione 3D del trasporto di particelle colloidali per la nanoremediation di acquiferi contaminati
A Posit Based Multiply-accumulate Unit with Small Quire Size for Deep Neural Networks (2022)

Posit is a numerical representation that is especially focused on deep neural networks (DNNs). However, a specific register called quire is necessary for a posit multiply-accumulate (MAC) unit to ensure the calculation accuracy. In this paper, we proposed posit based MAC unit that can optimize quire size according to target applications. We also develop the DNN library to explore quire size of proposed MAC unit. Experimental result with ResNet-9 showed that we achieved the same level of accuracy as Deep Positron but with the area reduction of 43%.
An efficient algorithm for optimal margin maximization in multicarrier communication systems (2003)

We present a computationally efficient, integer-bit power allocation algorithm for discrete multitone modulation (DMT) which optimally maximizes the performance margin. Using efficient lookup table searches and a Lagrange multiplier bisection search, our algorithm converges faster to the optimal solution than existing optimal techniques and can replace the use of suboptimal methods because of its low computational complexity. A fast algorithm is developed and pseudocode is given as well as numerical and qualitative comparisons to existing methods.
Cytokine Secretion by Cystic Fibrosis Airway Epithelial Cells (2003)

It is controversial whether mutations in cystic fibrosis transmembrane conductance regulator intrinsically dysregulate inflammation. We characterized passage 2 human tracheobronchial epithelial cell cultures morphologically and physiologically and determined whether cytokine production or nuclear factor-kappaB activation was systematically altered in cystic fibrosis (CF) cells. Non-CF and CF cells originating from a total of 33 and 25 lungs, respectively, were available for culture on plastic or at an air-liquid interface until well differentiated. Forskolin-stimulated short-circuit currents were present in representative polarized non-CF cultures and were absent in CF cultures, whereas uridine 5'-triphosphate-stimulated currents were present in both. Constitutive or interleukin (IL)-1beta-induced IL-8 or IL-6 secretion or nuclear factor-kappaB activity was not significantly different between non-CF and CF cells. The cytokines regulated upon activation, normal T cell expressed and secreted (RANTES) and IL-10 were not detectable. Stimulation with tumor necrosis factor-alpha or a synthetic toll-like receptor 2 agonist or variable doses and times of Staphylococcus aureus culture filtrate revealed a single dose- and time-dependent difference in IL-8 production by CF cells. Interestingly, although IL-8 secretion after stimulation with Pseudomonas aeruginosa filtrates was not greater in CF cells in the absence of human serum, it was variably greater in its presence. Thus, although exaggerated responses may develop under certain conditions, our results do not support an overall intrinsically hyperinflammatory phenotype in CF cells.
Hierarchical Logic Structures Based on Responsive Fluorescent Gold Nanoclusters (2014)

Logic with Gold Clusters. Gold nanoclusters can be used for the development of hierarchical logic structures. This is based on the reversible change in the fluorescence of the clusters at different pH of the medium, its temperature and metal ion concentration dependence.
Surface Based Differential Forms (2005)

Higher-order basis functions have been constructed for surface-based differential forms that are used in engineering simulations. These surface-based forms have been designed to complement the volume-based forms present in EMSolve , a finite element code. The basis functions are constructed on a reference element and transformed, as necessary, for each element in space. Lagrange polynomials are used to create the basis functions. This approach is a necessary step in creating a hybrid finite-element/integral-equation time-domain code for electromagnetic analysis.
ChemInform Abstract: Fluoro‐Sulfur‐Containing Olefins cis‐RSCH2CH=CHCH2SR (R: C6F5, p‐C6HF4 and p‐C6H4F). (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Stability of Fe- and Zn-Promoted Mo/ZSM-5 Catalysts for Ethane Dehydroaromatization in Cyclic Operation Mode (2018)

The stability of Fe- and Zn-promoted Mo/ZSM-5 catalysts was studied toward the ethane dehydroaromatization reaction. To elucidate the catalyst deactivation and regeneration mechanism, the catalytic performance was evaluated during five consecutive reaction–regeneration cycles. The addition of Zn to Mo/ZSM-5 resulted in an initial increase in aromatic selectivity; however, the loss of about 50% Zn resulted in a total decrease in aromatic selectivity over five reaction and regeneration cycles. The addition of Fe to Mo/ZSM-5 resulted in no decrease in aromatic selectivity or aromatic yield throughout these reaction cycles. The formation of carbon nanotubes was observed on the Fe-promoted Mo/ZSM-5 catalyst, which was believed to improve gas diffusion to micropores. The presence of Fe- and Mo-agglomerated particles on the catalyst surface was observed at low Fe/Mo atomic ratios, resulting in the formation of base-grown carbon nanotubes. When the Fe/Mo atomic ratio increased, the agglomerated particles were able to leave the zeolite surface, resulting in the formation of tip-growth carbon nanotubes. The temperature-programmed reduction profile of the Fe-promoted Mo/ZSM-5 catalyst also suggested the formation of a more stable Mo and/or Fe species at 615 °C, enhancing carbon nanotube formation. The addition of Fe in the bipromoted Mo/ZSM5 catalyst was found to stabilize the catalyst surface and reduce its Zn loss.
ChemInform Abstract: MAGNESIUM BROMIDE INDUCED REARRANGEMENTS OF α,β‐EPOXYSILANES (1976)

Abstract Die Epoxysilane (I) liefern mit Magnesiumbromid bei Raumtemperatur bzw. 0°C unter Ringspaltung die Bromhydrine (II), wobei aus (Ib) bei längerer Reaktionszeit und höherer Reaktionstemperatur (ca.
Synthesis and Evaluation of 99mTc-Labeled PSMA-Targeted Tracers Based on the Lys-Urea-Aad Pharmacophore for Detecting Prostate Cancer with Single Photon Emission Computed Tomography (2023)

Prostate-specific membrane antigen (PSMA) is a well-validated prostate cancer marker but reported PSMA-targeted tracers derived from the Lys-urea-Glu pharmacophore including the clinically validated [<sup>99m</sup>Tc]Tc-EDDA/HYNIC-iPSMA have high off-target uptake in kidneys, spleen, and salivary glands. In this study, we synthesized and evaluated three novel <sup>99m</sup>Tc-labeled PSMA-targeted tracers and investigated if the tracers derived from the Lys-urea-Aad pharmacophore could have minimized uptake in off-target organs/tissues. In vitro competition binding assays showed that compared with HYNIC-iPSMA, the three novel ligands had slightly weaker PSMA binding affinity (average K<sub>i</sub> = 3.11 vs. 8.96-11.6 nM). Imaging and ex vivo biodistribution studies in LNCaP tumor-bearing mice showed that [<sup>99m</sup>Tc]Tc-EDDA/HYNIC-iPSMA and the three novel tracers successfully visualized LNCaP tumor xenografts in SPECT images and were excreted mainly via the renal pathway. The average tumor uptake at 1 h post-injection varied from 5.40 to 18.8%ID/g, and the tracers derived from the Lys-urea-Aad pharmacophore had much lower uptake in the spleen and salivary glands. Compared with the clinical tracer [<sup>99m</sup>Tc]Tc-EDDA/HYNIC-iPSMA, the Lys-urea-Aad-derived [<sup>99m</sup>Tc]Tc-EDDA-KL01127 had lower background uptake and superior tumor-to-background contrast ratios and is therefore promising for clinical translation to detect prostate cancer lesions with SPECT.
The Sequoia 2000 electronic repository (1995)

A major effort in the Sequoia 2000 project was to build a very large database of Earth Science information. However, without the means to efficiently and effectively locate required information and to browse its contents, this vast database would rapidly become unmanagable and eventually unusable. The &amp;quot;Electronic Repository&amp;quot; project of Sequoia 2000 was intended to address these problems by the development of indexing and retrieval software incorporated into the POSTGRES database management system. This article will describe the elements of the Electronic Repository project for Sequoia 2000, including the design of probabilistic indexing and retrieval for text documents in POSTGRES, and the development of algorithms for automatic geo-referencing of text documents and segmentation of full texts into topically coherent segments for improved retrieval. Graphical interfaces to support these retrieval features will also be described. 1 Introduction Global change researchers, studying phenom...
Nanoparticles of the poly([N-(2-hydroxypropyl)]methacrylamide)-b-poly[2-(diisopropylamino)ethyl methacrylate] diblock copolymer for pH-triggered release of paclitaxel (2015)

The potential of self-assembled nanoparticles for <italic>in vitro</italic> cytostatic activity has been explored on cancer cells.
A derivative of the glycopeptide A40926 produced by inactivation of the Î²-hydroxylase gene in Nonomuraea sp. ATCC39727 (2006)

The actinomycete Nonomuraea sp. ATCC39727 produces the glycopeptide A40926. In the corresponding dbv cluster, ORF28 encodes a putative hydroxylase. A gene replacement mutant of ORF28 in Nonomuraea produces a small amount of an A40926-related metabolite, 16 amu smaller than the parent compound, which was identified as the desoxyderivative of A40926 lacking the beta-hydroxyl group on the tyrosine moiety. This result demonstrates that ORF28 is actually involved in the formation of the beta-hydroxytyrosine residue present in A40926. The formation of an altered glycopeptide and the inability to rescue A40926 production upon feeding free beta-hydroxytyrosine are consistent with the possibility that, in contrast to balhimycin formation, hydroxylation occurs after tyrosine activation by the nonribosomal peptide synthetase.
ChemInform Abstract: Elucidation of Accelerated Blood Clearance Phenomenon Caused by Repeat Injection of PEGylated Nanocarriers. (2010)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Centrally bradykinin B2-receptor-induced hypertensive and positive chronotropic effects are mediated via activation of the sympathetic nervous system (1999)

Our data suggest that the hypertensive and positive chronotropic effects induced by i.c.v. bradykinin are due to stimulation of sympathoneuronal rather than sympathoadrenal pathway in vivo.
In vivo validation of DNA adduct formation by estragole in rats predicted by physiologically based biodynamic modelling (2012)

Estragole is a naturally occurring food-borne genotoxic compound found in a variety of food sources, including spices and herbs. This results in human exposure to estragole via the regular diet. The objective of this study was to quantify the dose-dependent estragole-DNA adduct formation in rat liver and the urinary excretion of 1'-hydroxyestragole glucuronide in order to validate our recently developed physiologically based biodynamic (PBBD) model. Groups of male outbred Sprague Dawley rats (n = 10, per group) were administered estragole once by oral gavage at dose levels of 0 (vehicle control), 5, 30, 75, 150, and 300mg estragole/kg bw and sacrificed after 48h. Liver, kidney and lungs were analysed for DNA adducts by LC-MS/MS. Results obtained revealed a dose-dependent increase in DNA adduct formation in the liver. In lungs and kidneys DNA adducts were detected at lower levels than in the liver confirming the occurrence of DNA adducts preferably in the target organ, the liver. The results obtained showed that the PBBD model predictions for both urinary excretion of 1'-hydroxyestragole glucuronide and the guanosine adduct formation in the liver were comparable within less than an order of magnitude to the values actually observed in vivo. The PBBD model was refined using liver zonation to investigate whether its predictive potential could be further improved. The results obtained provide the first data set available on estragole-DNA adduct formation in rats and confirm their occurrence in metabolically active tissues, i.e. liver, lung and kidney, while the significantly higher levels found in liver are in accordance with the liver as the target organ for carcinogenicity. This opens the way towards future modelling of dose-dependent estragole liver DNA adduct formation in human.