gebhart/patrepeval huggingface dataset:
An Operational Superresolution Approach for Multi-Temporal and Multi-Angle Remotely Sensed Imagery (2012)

In this paper we propose an operational superresolution (SR) approach for multi-temporal and multi-angle remote sensing imagery. The method consists of two stages: registration and reconstruction. In the registration stage a hybrid patch-based registration scheme that can account for local geometric distortion and photometric disparity is proposed. Obstacles like clouds or cloud shadows are detected as part of the registration process. For the reconstruction stage a SR reconstruction model composed of the L1 norm data fidelity and total variation (TV) regularization is defined, with its reconstruction object function being efficiently solved by the steepest descent method. Other SR methods can be easily incorporated in the proposed framework as well. The proposed algorithms are tested with multi-temporal and multi-angle WorldView-2 imagery. Experimental results demonstrate the effectiveness of the proposed approach.
Melanoma primario de mucosa de cavidad nasal. Presentación de un caso (2014)

El melanoma de la mucosa es una entidad poco frecuente originada de los melanocitos, que tiene una presentacion asintomatica en la mayoria de los casos y un mal pronostico. Muchos melanomas ocurren en sitios ocultos y de dificil acceso lo cual contribuye al diagnostico tardio. Se presenta un caso de melanoma maligno de fosa nasal en una paciente femenina de 73 anos, de piel blanca con historia historia de obstruccion nasal de varios meses de evolucion. Acude a consulta por sangramiento nasal y se realiza exeresis de posible polipo de aspecto ulceronecrotico de fosa nasal izquierda. El diagnostico histologico e inmunohistoquimico fue de un melanoma maligno de celulas epitelioides, con celulas claras y pequenas de mucosa. Se envia al Instituto Nacional de Oncologia y Radiologia para completar tratamiento donde se le realiza rinomaxilectomia de infra y mesoestructura izquierda y se confirma el diagnostico.
An Efficient Technique for In-order Packet Delivery with Adaptive Routing Algorithms in Networks on Chip (2010)

Although adaptive routing algorithms promise higher communication performance, as compared to deterministic routing algorithms, they suffer from the out-of-order packet delivery problem. In the context of Network on Chip, the area and computational overhead of ordering packets at the destination is high and may reverse any gain achieved through the use of adaptivity of the routing algorithm. In this paper, we describe a novel scheme for ensuring in-order packet delivery while retaining the performance advantages of adaptive routing. The hardware architecture of a router that supports the proposed scheme is described. Although the basic idea in our proposal is topology independent we evaluate and compare the performance of our scheme with both deterministic as well as adaptive routing algorithms for 2D mesh NoC. As compared to the XY routing algorithm, our technique significantly reduces the packet delay and improves the saturation point. The impact on router area and power dissipation is also discussed. Although the power consumption of routers increase, the energy consumption per flit increases less than 2% on average, since the higher performance allows for draining more traffic during a certain time window.
Cover Feature: Late‐Stage Installation of Dehydroamino Acid Motifs into Peptides Enabled by an N‐Chloropeptide Strategy (Chem. Eur. J. 36/2022) (2022)

A N-chloropeptide strategy enables the rapid construction of ΔAA-containing peptides. The quinuclidine (ABCO)-catalyzed N-chlorination of peptide bonds and the subsequent β-elimination of N-chloroamide efficiently provides ΔAA-containing peptides in high yield. The strategy enables the late-stage installation of ΔAA motifs into oligopeptides that have already been constructed, including into a macrocyclic peptide. More information can be found in the Research Article by T. Nanjo, Y. Takemoto, and co-workers (DOI: 10.1002/chem.202201120).
VHF data link: a demonstration using the ACARS protocol (2003)

During the period 28 June-1 July 1999, The MITRE Corporation conducted a demonstration of a VHF data link system using a text message sent to participating Addressing and Reporting System (ACARS)-equipped aircraft over the VHF frequency 131.55. Two demonstration systems were deployed in Taiwan ROC: one at CKS International Airport and one at Kaohsiung International Airport. This experimental data link capability was used to demonstrate the effectiveness of a digital data link system using equipment already used for airline business operations. Consequently, the airlines did not have to add any special avionics equipment in order to receive the data link message. For this demonstration, the data link text was a digital Automated Terminal Information Service (DATIS) message that was uplinked to participating aircraft. While DATIS itself is not a new capability, the objective of the demonstration was to show how a simple controller-pilot communication could be performed with a VHF data link.
A Linear Solution Method of Generalized Robust Chance Constrained Real-time Dispatch (2018)

In this letter, a novel solution method of generalized robust chance constrained real-time dispatch (GRCC-RTD) considering wind power uncertainty is proposed. GRCC models are advantageous in dealing with distributional uncertainty, however, they are difficult to solve because of the complex ambiguity set. By constructing traceable counterparts of the robust chance constraints and using the reformulation linearization technique, the model is equivalently transformed into a deterministic linear programming problem, which can be solved efficiently by off-the-shelf solvers. Numerical results verify the effectiveness and efficiency of the approach.
Atlas of Urodynamics (2007)

Section One - Patient evaluation. Overview. Pre-urodynamic evaluation. Section Two - Techniques. Cystometry. Leak Point Pressure. Uroflowmetry. Electromyography. Urethral pressure measurement. Synchronous pressure/uroflow. Video-urodynamics. Sphincter electromyography. Section Three - Diagnosis. A Neuro-urology. Normal and abnormal physiology of micturition. Spinal cord injury. Cerebrovascular accident, Parkinson's Disease and other intracranial diseases. Multiple sclerosis and other demyelinating disorders. Diabetes Mellitus. Cauda equina, Infections and other spinal diseases. B Male voiding disorders. BPH, bladder neck obstruction and prostatitis. Post-prostatectomy incontinence. C Female Urology. Stress incontinence. Mixed incontinence. Overactive bladder. Bladder outlet obstruction. Pelvic organ prolapse. Leak point pressure in stress incontinence. Painful bladder syndrome and interstitial cystitis. D Pediatrics, geriatrics and bladder reconstruction. Pediatric urodynamics. Geriatric urodynamics. Urodynamic evaluation of urinary tract reconstruction. Appendix. ICS recommendations on good urodynamic practice
Anti-oxidants modulate protein phosphatase 2A (PP2A) activity to counteract cigarette smoke generated reactive oxygen species (2012)

Introduction

Phosphatases are redox regulated and play important roles in inflammatory signaling. Protein phosphatase 2A (PP2A) activity can be modified by reactive oxygen species (ROS) produced by numerous stimuli, including cigarette smoke (CS).

Aims and objectives

We examined whether the alteration of an anti-oxidant, glutathione peroxidase-1 (GPx-1), in mice could affect phosphatase response against CS and impact on CS-induced emphysema.

Methods

Wild-type, GPx-1 overexpressing and knockout mice were exposed to short and long term cigarette smoke. Inflammatory responses and phosphatase activities were determined from lung tissue.

Results

Over-expression of GPx-1 protected CS-induced inflammation and airway enlargement. Knockdown of GPx-1 resulted in an exaggerated emphysema phenotype, correlating with low PP2A activity levels. Induction of PP2A activity coincided with increased protein tyrosine phosphatase 1B (PTP1B) activity and subsequent tyrosine dephosphorylation of the catalytic subunit of PP2A (Tyr307).

Conclusions

Therefore, PP2A is redox regulated by GPx-1 and contributes to the inflammatory and proteolytic responses that occur in CS driven diseases. Targeting the PP2A pathway may be effective means of treating COPD and other diseases where inflammation plays a central role.
Mixed tetrahaloborate ions. Detection and study by nuclear magnetic resonance (1972)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMixed tetrahaloborate ions. Detection and study by nuclear magnetic resonanceJ. S. Hartman and G. J. SchrobilgenCite this: Inorg. Chem. 1972, 11, 5, 940–951Publication Date (Print):May 1, 1972Publication History Published online1 May 2002Published inissue 1 May 1972https://pubs.acs.org/doi/10.1021/ic50111a005https://doi.org/10.1021/ic50111a005research-articleACS PublicationsRequest reuse permissionsArticle Views449Altmetric-Citations53LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Bipolar polygenic loading and bipolar spectrum features in major depressive disorder (2014)

Bipolar genetic loading appeared to be associated with bipolar-like presentation in major depressive disorder in the primary analysis. However, the results were at most inconclusive because of lack of replication. Replication efforts were challenged by different ascertainment and assessment strategies in the different cohorts. The methodological approach described here may prove useful in applying genetic data to clarify psychiatric nosology in future studies.
Measurement and characterization of RF nonuniformity over the heart at 3T using body coil transmission (2008)

The in-plane B1+ variation over the LV at 3T with body-coil transmission is on the order of 32% to 63% and is predominantly unidirectional in short-axis slices. Reproducible B1+ measurements over the whole heart can be obtained in a single breathhold of 16 heartbeats.
A Mouse Model of Timothy Syndrome: a Complex Autistic Disorder Resulting from a Point Mutation in Cav1.2 (2012)

Timothy Syndrome (TS) arises from a point mutation in the human voltage-gated L-type Ca<sup>2+</sup> channel (Cav1.2). TS is associated with cardiac arrhythmias and sudden cardiac death, as well as congenital heart disease, impaired cognitive function, and autism spectrum disorders. TS results from a de novo gain-of-function mutation which affects the voltage dependent component of Cav1.2 inactivation. We created a knock-in TS mouse. No homozygous TS mice survived, but heterozygous TS2-NEO mice (with the mutation and the neocassette in situ) had a normal outward appearance and survived to reproductive age. Previously, we have demonstrated that these mice exhibit the triad of Autistic traits. In this paper we document other aspects of these mice including Cav1.2 isoform expression levels, normal physical strength, brain anatomy and a marked propensity towards self-injurious scratching. Gross brain anatomy was not markedly different in TS2-NEO mice compared to control littermates, and no missing structures were noted. The lack of obvious changes in brain structure is consistent with theTS2-NEO mice may provide a significant tool in understanding the role of calcium channel inactivation in both cardiac function and brain development.
Three-Dimensional Visualization of Gas Evolution and Channel Formation inside a Lithium-Ion Battery (2016)

Gas generation within lithium ion batteries (LIBs) gives rise to safety concerns that question their applicability. By employing synchrotron X-ray imaging, the gas and channel evolution occurring in an operating LIB have been directly visualized in their inherent 3D state as a function of discharge and charge. Using the spatial 3D distribution of gas bubbles and channels, the active particles that dictate the performance of a functional LIB were identified and visualized in 3D. Delithiation and lithiation are interpreted as the process of activating particles continuously in a step-by-step way. The present work not only demonstrates the generation and evolution of gas within LIB in 3D, but also reveals the distribution of active particles for the first time. These fundamentally findings presented here shed light on a range of processes that could not previously be characterized in 3D and can provide practical guidance for the design of next-generation LIBs with improved safety.
A matrix math facility for Power ISA(TM) processors (2021)

Power ISA(TM) Version 3.1 has introduced a new family of matrix math instructions, collectively known as the Matrix-Multiply Assist (MMA) facility. The instructions in this facility implement numerical linear algebra operations on small matrices and are meant to accelerate computation-intensive kernels, such as matrix multiplication, convolution and discrete Fourier transform. These instructions have led to a power- and area-efficient implementation of a high throughput math engine in the future POWER10 processor. Performance per core is 4 times better, at constant frequency, than the previous generation POWER9 processor. We also advocate the use of compiler built-ins as the preferred way of leveraging these instructions, which we illustrate through case studies covering matrix multiplication and convolution.
HIERARCHICAL POROUS MATERIALS: CAPILLARIES IN NANOPOROUS CARBON (2009)

A hierarchical carbon material containing nanopores (micropores and mesopores) and micrometric sized capillaries (macropores) is produced using a combination of hard and soft templates. The hard template is a polypropylene (PP) cloth which decomposes during pyrolysis leaving a macroporous structure. The soft template is a cationic polyelectrolyte which stabilizes the resorcinol/formaldehyde (RF) resin porous structure during drying to give a nanoporous RF resin. The method produces a nanocomposite of the porous RF resin with an imbibed PP cloth. The composite is then pyrolyzed in a inert gas atmosphere to render a carbon material having macropores as well as micro/mesopores. The material exhibits both a large surface area ( S BET = 742 ± 2 m 2 / g ) due to nanopores and goof fluid permeability due to micrometric sized pores. The macropores can be oriented during fabrication. The nanoporous surface can be used to support metal nanoparticles for fuel cell while the macropores allow easy flux of gas and liquids through the monolithic material.
Structure study of host–guest molecular association in solution and in the solid state (1993)

A correlation between the mechanism of 1H NMR shift of a chiral guest by association with an optically active host compound in solution and in the solid state is revealed by an X-ray analysis of the host-guest inclusion crystal.
Use of Advanced Technologies and Information Solutions for North Sea Offshore Assets: Ambitious Changes and Socio-Technical Dimensions (2006)

The use of various forms of advanced technologies and information solutions are in common place to manage industrial assets today. This is widely seen as the way forward in various industrial sectors owing to range of commercial benefits offered by new technologies and its importance to gain competitive advantage. The objective of this paper is to describe such an ongoing major technology-dependent re- engineering process termed Integrated eOperations in oil and gas exploration and production business in North Sea since 2004-2005, and to highlight the nature of ambitious techno-managerial changes and its critical socio-technical dimensions. The change process focuses on a new development path based on 24/7 online real-time operations, with direct implications on organizational forms and managerial tasks. Given the nature and the scale of ongoing change processes, there are emerging concerns that increasing complexities, ill-defined interfaces can easily lead to serious vulnerabilities and major risks. To avoid such undesirable circumstances that will surely have long-term commercial repercussions, a holistic socio-technical consideration and early measures to ensure fully-functional and fail-safe system are absolutely necessary.
Supplementary Figure 1 from Phase Ia Study of Anti-NaPi2b Antibody–Drug Conjugate Lifastuzumab Vedotin DNIB0600A in Patients with Non–Small Cell Lung Cancer and Platinum-Resistant Ovarian Cancer (2023)

&lt;p&gt;Supplementary Figure S1. CA125 response to lifastuzumab vedotin in ovarian cancer patients. All patients with radiographic responses also had {greater than or equal to}50 decrease in CA125 from baseline levels.&lt;/p&gt;
A Synergistic Nano‐Zerovalent Iron‐Hydrogen Peroxide Technology for Insensitive Munitions Wastewater Treatment (2022)

Abstract The U.S. Army is phasing out legacy munitions compounds that are prone to accidental detonation and replacing them with insensitive munitions compounds (IMCs). The major IMCs, namely 3‐nitro‐1,2,4‐triazol‐5‐one (NTO), 2,4‐dinitroanisole (DNAN), and nitroguanidine (NQ), are not compatible with existing munitions wastewater treatment technologies such as granular activated carbon due to their high water solubilities. In this study, a two‐stage process employing nanoscale zero‐valent iron (nZVI) and hydrogen peroxide (H 2 O 2 ) was evaluated as a potential technology for the destructive treatment of IMC wastewater. In the first stage, nZVI rapidly and completely degraded all three IMCs and generated dissolved Fe(II). NTO and DNAN were degraded via nitro reduction to 3‐amino‐1,2,4‐triazol‐5‐one and 2,4‐diaminoanisole, respectively. In the second stage, H 2 O 2 was added to oxidize the IMC reduction products through Fenton reaction utilizing the dissolved Fe(II) from the first stage. nZVI‐treated NTO and DNAN samples showed 66 % and 63 % TOC removal after oxidation, respectively. In contrast, NQ reduction products exhibited negligible mineralization. The results with individual IMCs were confirmed by an experiment using synthetic wastewater containing all three IMCs. This study illustrates the potential feasibility of a synergistic and destructive nZVI−H 2 O 2 technology for treating IMC‐laden wastewaters at military facilities.
Evolution of a Trophoblastic Tumor From an Endometrioid Carcinoma—A Morphological and Molecular Analysis (2011)

We report the clinicopathological and molecular characteristics of a rare uterine endometrioid carcinoma with a nongestational trophoblastic neoplastic component that was composed of both choriocarcinoma and epithelioid trophoblastic tumor. Molecular genetic analysis showed a clonal evolution from endometrioid carcinoma to trophoblastic tumor. The findings from this case have both diagnostic and biological implications that may inspire future studies on the pathogenic mechanisms by which cancer stem cells assume aberrant differentiation programs and the molecular switch(es) that initiates trophoblastic differentiation in adult tumor tissues.
FPGA based accelerator for visual features detection (2015)

In the context of obstacle detection and tracking for a vision-based ADAS (Advanced Driver Assistance System), one mandatory task is vehicle localization. Vision-based SLAM (Simultaneous Localization and Mapping) proposes to solve this problem by combining the estimation of the vehicle state (localisation : position and orientation) and an incremental modelling of the environment using a perception module (feature detection and matching) in images acquired using one camera or more. Such a perception module requires an important computational load that highly affects the latency and the throughput of the system. Our goal is to implement the SLAM functionality on a low power consumption mixed hardware and software architecture (using a co-design approach) based on a Xilinx Zynq FPGA. This device includes logic cells that allows to speed-up the perception tasks to meet the real-time constraint of an ADAS. In this paper, we present the implementation of two hardware components : a FAST (Features from Accelerated Segment Test) features detector and a parametrizable corner refinement module (Non Maxima Suppression - NMS).
Detection of the Gene Rearrangement in Chronic Myelogenous Leukemia with Biotinylated Gene Probes (1989)

The breakpoint cluster region gene rearrangement associated with chronic myelogenous leukemia is becoming important in the diagnosis and management of the disease. At this time, the ability to demonstrate the gene rearrangement is limited to a few research laboratories. The problem results partially from unfamiliarity of medical laboratory personnel with DNA technology, but more because of the restricted use of radiolabeled phosphorus in hospital laboratories. With the introduction of biotinylated deoxynucleotides, nucleic acid hybridization procedures can now be performed without the use of radioisotopically labeled gene probes. This article describes the use of biotin-labeled gene probes to detect the gene rearrangement of the breakpoint cluster region of chromosome 22 in chronic myelogenous leukemia. The techniques are reproducible, sensitive, and safe. With the procedures described in this article, the assay can become more available to medical laboratories interested in offering this diagnostic and decision-making tool.