gebhart/patrepeval huggingface dataset:
Method to update the feedback control filter coefficients under active noise control (2002)

The active noise control system requires the process of identifying the secondary and the feedback paths previous to updating the coefficients of the noise control filter. These paths, however, are continuously changing in practical systems after the identification. This change inevitably degrades the performance of the system. The authors have already presented a method to update the coefficients of the secondary path filter modeling the former path under active noise control. This paper hence proposes another method to refresh the coefficients of the feedback control filter modeling the latter path. For this refreshment, the method forms two independent equations by using the estimation error involved in the coefficients of the noise control filter. This paper also introduces a system identification technique to solve the equations.
Research on clustering trajectories for moving objects (2011)

Cluster analysis, as an important research branch of data mining, according to the information found in the data describing objects and relationship, and according to the basic clustering analysis principle of the similarity between objects in the ensemble and the maximum of similarity between objects of minimizing, will classify objects into close eye independent clustered close. A few days ago, because the data of each application database is getting bigger and bigger, the clustering analysis is widely applied in all kinds of research fields, and becomes a very active research subject in the area of data mining. With the development of data collection technology, computer network and database technology, the various complex types of data grows explosively, so new data mining technology need to be explored urgently for complex data types. This paper carries on a research on two problems the space the moving object clustering and moving object trajectory clustering, from the views of the improvement of mobile object clustering space effect, mobile object clustering effect, enhancing algorithm time complexity and reducing input parameter sensitivity, which need solutions badly.
A Highly Efficient Synthesis of 1-Methyl-, 1-Benzyl-, and 1-Phenyl-1,2,3,4-tetrahydroisoquinolines by a Modified Pummerer Reaction (1997)

f)-I-Methyl-(13b), '(f)-I-benzyl-(13c), and (f)-I-phenyl-(13d)-1,2,3,4-tetrahydroisoquinolines, which are supposed to participate in the pathogenesis of Parkinson's disease, were prepared by using a modified Pummerer reaction as a key step in excellent overall yields from the commercially available ketones (4 b -c).Isoquinoline alkaloids formed endogenously in mammals have received attention since they are supposed to participate in the pathogenesis of Parkinson's disease.'Recently, Takano et al. developed a route of synthesizing 1,2,3,4-tetrahydroisoquinolines (TIQs) via sulfoxide-mediated electrophilic intramolecular cyclization by Pummerer ~eaction.~In the preceding paper,' we reported two revised methods of Takano's TIQ synthesis; one is the use of trifluoroacetic anhydride (TFAA) in benzene at room temperature (Method A) and the other involves a sequential treatment with TFAA and BF,*E\O (Method B).Method A is only applicable to the synthesis of TIQs possessing OMe group in the benzene ring (ex.la).On the other hand, Method B is highly efficient for preparing TIQs which do not possess OMe group in the benzene ring (ex.lb).We also found that the formyl group used for N-protection plays an important role in effecting the intramolecular cyclization?In this paper we describe a highly efficient synthesis of I-methyl-, I-benzyl-and 1-phenyl-1,2,3,4tetrahydroisoquinolines (1-MeTIQ 1-BnTIQ, and 1-PhTIQ) which expands the utility of the modified Pummerer reaction.The target compounds are known to be present in mammalian brain, and 1-MeTIQ
Correction to “Transient-State Analysis of Human Isocitrate Dehydrogenase I: Accounting for the Interconversion of Active and Non-Active Conformational States” (2020)

ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to "Transient-State Analysis of Human Isocitrate Dehydrogenase I: Accounting for the Interconversion of Active and Non-Active Conformational States"Joseph V. RomanJoseph V. RomanMore by Joseph V. Roman, Trevor R. MelkonianTrevor R. MelkonianMore by Trevor R. Melkonian, Nicholas R. SilvaggiNicholas R. SilvaggiMore by Nicholas R. Silvaggihttp://orcid.org/0000-0003-0576-0714, and Graham R. Moran*Graham R. MoranMore by Graham R. Moranhttp://orcid.org/0000-0002-6807-1302Cite this: Biochemistry 2020, 59, 35, 3284Publication Date (Web):August 26, 2020Publication History Received5 August 2020Published online26 August 2020Published inissue 8 September 2020https://pubs.acs.org/doi/10.1021/acs.biochem.0c00649https://doi.org/10.1021/acs.biochem.0c00649correctionACS PublicationsCopyright © 2020 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views640Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (458 KB) Get e-Alertsclose Get e-Alerts
Impact of Esters of Mono- and Dicarboxylic Acids on Diesel Fuel Quality (1999)

The objective of this work was to assess how esters of mono- and dicarboxylic acids of different structure affect diesel fuel quality, by measuring cetane numbers and cold flow properties of blends of the esters under investigation with gasoil. An increase in either the chain length of the normal alcohol used for the esterification or the chain length of the mono- or dicarboxylic acid involved in the esterification improves the cetane number. Among the fatty acid esters of the same molecular type, those having the carboxylic group close to one end of the molecule have better ignition quality, whereas those having the ester group around the middle of the molecule appear to have better cold flow performance. Oleates combine good ignition quality with adequate cold flow performance, whereas the high oxygen content of some diesters seems to be an extra advantage.
Status of the Swiss LCT-coil (1983)

The Swiss coil is a forced flow coil cooled by supercritical helium. Following, a brief review of the design considerations, some of its specific features, and the progress in fabrication are described. Next a discussion of both the instrumentation and the cryogenic characteristics of the coil are presented.
In situ formation of H-bonding imidazole chains in break-junction experiments (2020)

As a small molecule possessing both strong H-bond donor and acceptor functions, 1H-imidazole can participate in extensive homo- or heteromolecular H-bonding networks. These properties are important in Nature, as imidazole moieties are incorporated in many biologically-relevant compounds. Imidazole also finds applications ranging from corrosion inhibition to fire retardants and photography. We have found a peculiar behaviour of imidazole during scanning tunnelling microscopy-break junction (STM-BJ) experiments, in which oligomeric chains connect the two electrodes and allow efficient charge transport. We attributed this behaviour to the formation of hydrogen-bonding networks, as no evidence of such behaviour was found in 1-methylimidazole (incapable of participating in intramolecular hydrogen bonding). The results are supported by DFT calculations, which confirmed our hypothesis. These findings pave the road to the use of hydrogen-bonding networks for the fabrication of dynamic junctions based on supramolecular interactions.
Cosine similarity based fingerprinting algorithm in WLAN indoor positioning against device diversity (2015)

The fingerprinting location method is commonly used in WLAN indoor positioning system. Device diversity (DD) which leads to Received Signal Strength (RSS) value difference between the users' device and the reference device is becoming an increasingly important factor impacting the positioning accuracy. Thus, the device diversity is a key problem gained more and more attention in fingerprinting location system recently, which introduces many uncertainties to the positioning result. Traditionally, the Euclidean distance is widely adopted in fingerprinting method. However, when encountering with RSS value difference caused by device diversity, the localization performance is degraded significantly. Due to this problem, our paper proposes a method employing cosine similarity instead of the Euclidean distance to improve the positioning accuracy about 13.15% higher within 2 meters when device diversity exists in the positioning. The experiment results show that the proposed method presents a good performance without the expenses of computation caused by calibration method which is employed in many previous works.
Model of Electromagnetic Ion Cyclotron Waves in the Inner Magnetosphere (2014)

The evolution of He+-mode electromagnetic ion cyclotron (EMIC) waves is studied inside the geostationary orbit using our global model of ring current (RC) ions, electric field, plasmasphere, and EMIC waves. In contrast to the approach previously used by Gamayunov et al. (2009), however, we do not use the bounce-averaged wave kinetic equation but instead use a complete, nonbounce-averaged, equation to model the evolution of EMIC wave power spectral density, including off-equatorial wave dynamics. The major results of our study can be summarized as follows. (1) The thermal background level for EMIC waves is too low to allow waves to grow up to the observable level during one pass between the “bi-ion latitudes” (the latitudes where the given wave frequency is equal to the O+–He+ bi-ion frequency) in conjugate hemispheres. As a consequence, quasi-field-aligned EMIC waves are not typically produced in the model if the thermal background level is used, but routinely observed in the Earth's magnetosphere. To overcome this model-observation discrepancy we suggest a nonlinear energy cascade from the lower frequency range of ultralow frequency waves into the frequency range of EMIC wave generation as a possible mechanism supplying the needed level of seed fluctuations that guarantees growth of EMIC waves during one pass through the near equatorial region. The EMIC wave development from a suprathermal background level shows that EMIC waves are quasi field aligned near the equator, while they are oblique at high latitudes, and the Poynting flux is predominantly directed away from the near equatorial source region in agreement with observations. (2) An abundance of O+ strongly controls the energy of oblique He+-mode EMIC waves that propagate to the equator after their reflection at bi-ion latitudes, and so it controls a fraction of wave energy in the oblique normals. (3) The RC O+ not only causes damping of the He+-mode EMIC waves but also causes wave generation in the region of highly oblique wave normal angles, typically for θ > 82°, where a growth rate γ > 10−2rad/s is frequently observed. The instability is driven by the loss cone feature in the RC O+ distribution function, where ∂F/∂v⟂>0 for the resonating O+. (4) The oblique and intense He+-mode EMIC waves generated by RC O+ in the region L≈2–3 may have an implication to the energetic particle loss in the inner radiation belt.
Threshold windspeeds for sand on Mars: Wind tunnel simulations (1980)

Wind friction threshold speeds (u *t ) for particle movement (saltation) were determined in a wind tunnel operating at martian surface pressure with a 95 percent CO 2 and 5 percent air atmosphere. The relationship between friction speed (u * ) and free‐stream velocity (u ∞ ) is extended to the critical case for Mars of momentum thickness Reynolds numbers (Re θ ) between 425 and 2000. It is determined that the dynamic pressure required to initiate saltation is nearly constant for pressures between 1 bar (Earth) and 4 mb (Mars) for atmospheres of both air and CO 2 ; however, the threshold friction speed (u *t ) is about 10 times higher at low pressures than on Earth. For example, the u *t (Earth) for particles 210 µm in diameter is 0.22 m s −1 and the u *t (Mars, 5 mb, 200 K) is 2.2 m s −1 .
A blood collection device for diving into a leukocyte-depleted concentrated red cell and a fresh plasma in a closed system during blood donation. (1989)

A new blood collection device was developed, which consisted of a blood filter (Sepacell R-500) to remove leukocytes, a hollow-fiber module (BCC 400) to filtrate plasma from whole blood and two blood collection bags.Eleven units of 400ml whole blood fleshly collected were investigated. They had mean volume 456 (SD 8)ml with mean heamatocrit value 41.6 (SD 1.8)%, which were passed through the devices in mean time 9′42″ (SD 2′35″) and were divided directly into mean volume 326 (SD 17)ml of concentrated red cells (CRC) with mean heamatocrit value 65.7 (SD 5.0)% and 149 (SD 10)ml of plasma.In the CRC 95.6% of white blood cells and 98.8% of platelets were removed on average, while 81.0% of red blood cells were recovered. There were no significant differences between the pretreated whole blood and the treated CRC at the levels of ATP and 2, 3-DPG in red blood cells, osmotic fragility and the value of platelet factor 4, C3a and C5a in plasma. During 28 days storage, ATP, 2, 3-DPG, free hemoglobin and pH levels in the treated CRC showed the same changes as those in the CRC prepared with centrifugation as usual.These results indicate that the leukocyte-depleted CRC passed through this device can be simply prepared in a closed system at donating blood, so that their shelf-life will have to be as long as that of conventional CRC.
Increased Risk for Hip Fractures among Patients with Cholangitis: A Nationwide Population-Based Study (2018)

Cholangitis is associated with higher risk for hip fracture, especially among young subjects free from medical comorbidities.
Fluorescence-Quenching Screening of Protein Kinase C Ligands with an Environmentally Sensitive Fluorophore (2011)

A novel fluorescence-quenching screening method for protein kinase C (PKC) ligands was developed utilizing solvatochromic fluorophores. Solvatochromic dyes, highly sensitive to the presence or the absence of competitive ligands in their binding to the C1b domain of PKCδ (δC1b), were combined with a known pharmacophoric moiety of 1,2-diacylglycerol (DAG) lactones, PKC ligands. Addition of δC1b to the fluorescent compounds caused a gradual increase in the fluorescent intensity in proportion to the increase of δC1b. As a competitive ligand was added to the complex of δC1b domain and fluorescent compounds, a gradual decrease in the fluorescent intensity was observed. The relative binding affinities of known ligands were successfully determined by this fluorescent method and corresponded well to the K(i) values measured by a radioisotope method. These results indicate that washing, which is a laborious step in binding evaluations, is not required for this environmentally sensitive fluorophore based system. Screening with the system was performed for 2560 preselected library compounds with possible pharmacophores, and some lead compounds were found. This fluorescence-based method could be applied widely to known ligand-receptor combinations.
Elementary and derived sensitivity information in chemical kinetics (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElementary and derived sensitivity information in chemical kineticsRichard Yetter, Luis Alejandro Eslava, Frederick L. Dryer, and Herschel RabitzCite this: J. Phys. Chem. 1984, 88, 8, 1497–1507Publication Date (Print):April 1, 1984Publication History Published online1 May 2002Published inissue 1 April 1984https://pubs.acs.org/doi/10.1021/j150652a011https://doi.org/10.1021/j150652a011research-articleACS PublicationsRequest reuse permissionsArticle Views69Altmetric-Citations21LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Efficient Synthesis of 3‐Substituted Indazoles Using Pd‐Catalyzed Intramolecular Amination Reaction of N‐Tosylhydrazones. (2004)

Abstract For Abstract see ChemInform Abstract in Full Text.
Whispering gallery modes of a curved antiresonant reflecting optical waveguide (1997)

The whispering gallery modes of a curved antiresonant reflecting optical waveguide are described and analyzed. We present a ray analysis method that can be used to derive an eigenmode equation and to analyze the loss characteristics of a waveguide in rectangular coordinates by using conformal transformation. With an optimized design of an antiresonant reflecting optical waveguide structure, the propagation loss of such a waveguide can be significantly reduced.
Down‐regulated expression of plant‐specific glycoepitopes in alfalfa (2008)

Compared with other plant expression systems used for pharmaceutical protein production, alfalfa offers the advantage of very homogeneous N-glycosylation. Therefore, this plant was selected for further attempts at glycoengineering. Two main approaches were developed in order to humanize N-glycosylation in alfalfa. The first was a knock-down of two plant-specific N-glycan maturation enzymes, beta1,2-xylosyltransferase and alpha1,3-fucosyltransferases, using sense, antisense and RNA interference strategies. In a second approach, with the ultimate goal of rebuilding the whole human sialylation pathway, human beta1,4-galactosyltransferase was expressed in alfalfa in a native form or in fusion with a targeting domain from N-acetylglucosaminyltransferase I, a glycosyltransferase located in the early Golgi apparatus in Nicotiana tabacum. Both knock-down and knock-in strategies strongly, but not completely, inhibited the biosynthesis of alpha1,3-fucose- and beta1,2-xylose-containing glycoepitopes in transgenic alfalfa. However, recombinant human beta1,4-galactosyltransferase activity in transgenic alfalfa completely prevented the accumulation of the Lewis a glycoepitope on complex N-glycans.
Serogrouping and subtyping of Legionella pneumophila with monoclonal antibodies (1983)

Monoclonal antibodies directed against Legionella pneumophila serogroups 1 to 6 were produced by fusing splenocytes of BALB/c mice with the Sp 2/0-Ag14 or the NSO mouse myeloma cell lines. Specificity of these antibodies was determined by indirect fluorescent-antibody staining: 8 reacted with L. pneumophila serogroup 1 and, respectively, 13, 6, 6, 5, and 10 reacted with serogroups 2, 3, 4, 5, and 6; all except 5 were serogroup specific, and none presented cross-reactions with six other species of Legionellaceae. Serogroup determination of 35 isolates of L. pneumophila with seven selected monoclonal antibodies resulted in correct serogrouping in all instances; a pool of the same seven monoclonal antibodies stained intensely all strains of L. pneumophila without any staining of the other species of Legionellaceae. When 24 serogroup 1 isolates of L. pneumophila were stained with eight serogroup 1-specific monoclonal antibodies, the staining patterns could be clustered in five distinct groups. These hybridomas thus represent an unlimited source of standard reagent that could be used in the detection and serogrouping of L. pneumophila; differences in staining patterns could be used as epidemiological markers for these bacteria.
Soft X-ray Laser Microscopy of Lipid Rafts towards GPCR-Based Drug Discovery Using Time-Resolved FRET Spectroscopy (2011)

Many signaling molecules involved in G protein-mediated signal transduction, which are present in the lipid rafts and believed to be controlled spatially and temporally, influence the potency and efficacy of neurotransmitter receptors and transporters. This has focus interest on lipid rafts and the notion that these microdomains acts as a kind of signaling platform and thus have an important role in the expression of membrane receptor-mediated signal transduction, cancer, immune responses, neurotransmission, viral infections and various other phenomena due to specific and efficient signaling according to extracellular stimuli. However, the real structure of lipid rafts has not been observed so far due to its small size and a lack of sufficiently sophisticated observation systems. A soft X-ray microscope using a coherent soft X-ray laser in the water window region (2.3–4.4 nm) should prove to be a most powerful tool to observe the dynamic structure of lipid rafts of several tens of nanometers in size in living cells. We have developed for the X-ray microscope a new compact soft X-ray laser using strongly induced plasma high harmonic resonance. We have also developed a time-resolved highly sensitive fluorescence resonance energy transfer (FRET) system and confirmed protein-protein interactions coupled with ligands. The simultaneous use of these new tools for observation of localization of G-protein coupled receptors (GPCRs) in rafts has become an important and optimum tool system to analyze the dynamics of signal transduction through rafts as signaling platform. New technology to visualize rafts is expected to lead to the understanding of those dynamics and innovative development of drug discovery that targets GPCRs localized in lipid rafts.