gebhart/patrepeval huggingface dataset:
Polypeptide fluoroacetate derivatives Synthesis and 19F n.m.r. (1988)

The synthesis and characterization of monofluoroacetyl (MFAc) functionalized haptens are described. These were covalently bound to polypeptide carriers (bovine serum albumin and poly‐ d ‐lysine) by primary amine/succinimide ester or primary amine/acid chloride coupling. Epitopic densities of the resulting antigens were determined by both 19 F n.m.r. and picryl sulfonic acid assays. 19 F n.m.r. experiments defining the stability of MFAc ester and amide linkages as a function of media (including in vitro ), time, and temperature are presented. These results indicate that MFAc functionalized antigens are well suited for further immunologic studies.
Securing the Internet of Things: An Ongoing Challenge (2020)

The challenges, bugs, and trouble spots that we've had in building and securing the Internet of Computers can provide a starting point for analyzing the challenges that will be manifested in this brave new world. Members of the IT community have their work cut out here.
Astronomy with your Personal Computer (1990)

The first edition of this very successful book was one winner of the Astronomical Society of the Pacific 'Astronomy Book of the Year' awards in 1986. There are a further seven subroutines in the new edition which can be linked in any combination with the existing twenty-six. Written in a portable version of BASIC, it enables the amateur astronomer to make calculations using a personal computer. The routines are not specific to any make of machine and are user friendly in that they require only a broad understanding of any particular problem. Since the programs themselves take care of details, they can be used for example to calculate the time of rising of any of the planets in any part of the world at any time in the future or past, or they may be used to find the circumstances of the next solar eclipse visible from a particular place. In fact, almost every problem likely to be encountered by the amateur astronomer can be solved by a suitable combination of the routines given in the book.
First Leptophobic Dark Matter Search from the Coherent–CAPTAIN-Mills Liquid Argon Detector (2022)

We report the first results of a search for leptophobic dark matter (DM) from the Coherent-CAPTAIN-Mills (CCM) liquid argon (LAr) detector. An engineering run with 120 photomultiplier tubes (PMTs) and 17.9×10^{20} protons on target (POT) was performed in fall 2019 to study the characteristics of the CCM detector. The operation of this 10-ton detector was strictly light based with a threshold of 50 keV and used coherent elastic scattering off argon nuclei to detect DM. Despite only 1.5 months of accumulated luminosity, contaminated LAr, and nonoptimized shielding, CCM's first engineering run has already achieved sensitivity to previously unexplored parameter space of light dark matter models with a baryonic vector portal. With an expected background of 115 005 events, we observe 115 005+16.5 events which is compatible with background expectations. For a benchmark mediator-to-DM mass ratio of m_{V_{B}}/m_{χ}=2.1, DM masses within the range 9 MeV≲m_{χ}≲50 MeV are excluded at 90% C. L. in the leptophobic model after applying the Feldman-Cousins test statistic. CCM's upgraded run with 200 PMTs, filtered LAr, improved shielding, and 10 times more POT will be able to exclude the remaining thermal relic density parameter space of this model, as well as probe new parameter space of other leptophobic DM models.
A system of IAC neural networks as the basis for self-organization in a sociological dynamical system simulation (1995)

This sociological simulation uses the ideas of semiotics and symbolic interactionism to demonstrate how an appropriately developed associative memory in the minds of individuals on the microlevel can self-organize into macrolevel dissipative structures of societies such as racial cultural/economic classes, status symbols and fads. The associative memory used is based on an extension of the IAC neural network (the Interactive Activation and Competition network). Several IAC networks act together to form a society by virtue of their human-like properties of intuition and creativity. These properties give them the ability to create and understand signs, which lead to the macrolevel structures of society. This system is implemented in hierarchical object oriented container classes which facilitate change in deep structure. Graphs of general trends and an historical account of a simulation run of this dynamical system are presented.
On the design of efficient experiments for choosing between two bernoulli populations (1980)

An experiment consists of taking samples one at a time from two Bernoulli populations. At the conclusion of the experiment one of the two populations is declared to have the higher probability of sucess.We propose two classes rules for sampling and for choosing a population which results which results good decisions made quickly.These rules are analysed and are compared suggested previously by means of Monte-Carlo simulations.
Anterior Approach as a Gold Standard Treatment for Cervical Spondylosis(<SPECIAL ISSUES>Cervical Spine) (2007)

頸部脊椎症は,加齢による脊椎,椎間板の退行変性に基づく疾患であり,椎間板の変性から始まり,亜脱臼,骨棘形成,後縦靭帯・黄色靭帯の肥厚により,脊髄および神経根が動的,静的に圧迫され生ずる疾患であるが,近年,高齢者の増加とともに頸部脊椎症の患者を治療する機会が増えている.また患者の訴える内容も,以前であれば歩行障害まで進行してから受診したのに対し,最近では上肢のしびれ,痛みでも,その原因の解明と治療を求めて来院するようになってきている.頸部脊椎症の外科治療においては,前方到達法と後方除圧の2つの選択肢があるが,前者は脊髄・神経根への圧迫を確実に除くことが可能であり,頸椎のalignmentを改善でき,侵襲が少なく,治療効果の切れ味という点で優れている.頸部脊椎症に対する前方アプローチによる手術手技は,Cloward法,Smith-Robinson法から始まって,現在までにさまざまな手技が行われてきたが,われわれが現在最もよく施行しているチタン製ケージを使用したSmith-Robinson法について,その手技およびpitfallについて述べる.
Regulation of T lymphocyte trafficking into lymph nodes during an immune response by the chemokines macrophage inflammatory protein (MIP)-1 alpha and MIP-1 beta. (1998)

By virtue of their target cell specificity, chemokines have the potential to selectively recruit leukocyte subpopulations into sites of inflammation. Their role in regulation of T lymphocyte traffic into lymph nodes during the development of an immune response has not previously been explored. The sensitization phase of contact hypersensitivity induced by the hapten, dinitrofluorobenzene (DNFB) in the mouse was used as a model of T lymphocyte trafficking in response to antigenic stimulation. Rapid accumulation of CD8+ and CD4+ T cells in the draining lymph nodes was closely associated with strongly enhanced expression of macrophage inflammatory protein (MIP)-1 alpha and MIP-1 beta mRNAs and proteins. Mast cells accumulating in the nodes during DNFB sensitization were the predominant source of MIP-1 beta, whereas MIP-1 alpha was expressed by multiple cell types. Neutralization of these chemokines profoundly inhibited T lymphocyte trafficking into lymph nodes and altered the outcome of a subsequent challenge to DNFB. Thus, beta-chemokines regulate T lymphocyte emigration from the circulation into lymph nodes during an immune response and contribute significantly to the immunologic outcome.
Innovative Work Scheme: Real Time Analysis During Well Test Operations (2012)

Abstract In 2007, a new Independent Brazilian Oil and Gas company acquired 21 exploration offshore blocks, increasing its portfolio up to 29 blocks by March 2009. Ambitious exploration and production goals were set, such as Drilling Commencement by Q3 2009, Minimum Well Drilling Commitments in four Basins by 2010/11, Initial Development in the Campos Basin and First Oil by 2012. The first three initial goals have already been met and the fourth one is well online to be met as expected with the FPSO already in the Brazilian coast. One of the key elements to reach these objectives is recognized to be the implementation of a focused innovative decision workflow, supported by a real time monitoring process from a cross-disciplinary Operations Support Center (OSC). This paper presents this innovative work scheme, based on a collaborative working environment between the operating and service companies during the well testing operations, with the most advanced monitoring and interpretation tools. It includes a concrete field case which resulted not only in improved risk identification, prevention and mitigation, but also in operational performance optimization. This case was a horizontal open hole test of 1080 mts with 90 deg deviation. The real-time collaboration resulted in significant rig time savings, mitigation of unexpected events consequences, and delivery of higher productivity comparing similar wells results in the area. This innovative decision workflow implemented in Brazil is considered as a high-technological reference model for operating companies, locally in Brazil and others around the world, to achieve success during challenging Well Testing operations.
Dispersion of nanodiamond into organic media by the use of fluoroalkyl end‐capped oligomers—applications to surface modification of poly(methyl methacrylate) with the dispersed nanodiamond (2005)

Abstract Self‐assembled fluorinated molecular aggregates formed by fluoroalkyl end‐capped oligomers were able to interact with nanodiamond powders to afford well‐dispersed fluorinated aggregates‐diamond nanocomposites in organic media, and these fluorinated aggregates‐diamond nanocomposites were applied to the surface modification of poly(methyl methacryate) films. Copyright © 2005 John Wiley &amp; Sons, Ltd.
Sinusoidal Smooth Pursuit Eye Tracking at Different Stimulus Frequencies: Position Error and Velocity Error Before Catch-Up Saccades in Schizophrenia and in Major Depressive Disorder (2009)

Eye tracking dysfunction in schizophrenia can be described as follows with regard to position error and velocity error: On the one hand, there is an increased position error tolerance largely independent of stimulus frequency, possibly due to an impairment of processing localization information. On the other hand, velocity processing is more severely impaired by an increase in stimulus frequency.
Computational study of millimeter-wave metal-pin photonic bandgap waveguides for use as ultrahigh-speed bandpass wireless interconnects (2004)

Much above present computer clock rates of about 3 GHz, problems with signal integrity, cross-coupling, and radiation may render continuous metallic interconnects impractical. An emerging possibility is to use bandpass wireless interconnects wherein the baseband digital bit stream amplitude-modulates a millimeter-wave carrier. This approach is enabled by the recent development of THz-class silicon transistors (R.F. Service, Science, vol. 293, no. 5531, p. 786, 2001) and advances in understanding the waveguiding physics provided by photonic bandgap (PBG) structures. In principle, bandpass wireless interconnects could transmit increasingly fast digital bit streams in smaller waveguides by modulating higher-frequency RF carriers. This paper is a computational-modeling study of a 2D PBG waveguiding structure which could be used to implement such a bandpass wireless interconnect. Using the finite-difference time-domain (FDTD) method, we study the transmission characteristics of a candidate PBG array of metal rods in air for the TM-polarization case. A frequency-independent surface impedance model (A. Taflove and S.C. Hagness, Computational Electrodynamics: The Finite-Difference Time-Domain Method, 2nd ed. Norwood, MA, Artech House, 2000) is used to permit estimation of the PBG stopband characteristics and the transmission losses of the PBG waveguide.
Isolation and identification of four cytokinins from wheat germ transfer ribonucleic acid (1970)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIsolation and identification of four cytokinins from wheat germ transfer ribonucleic acidW. John Burrows, Donald J. Armstrong, M. Kaminek, Folke Skoog, Robert M. Bock, Sidney M. Hecht, L. G. Dammann, Nelson J. Leonard, and John L. OccolowitzCite this: Biochemistry 1970, 9, 9, 1867–1872Publication Date (Print):April 28, 1970Publication History Published online1 May 2002Published inissue 28 April 1970https://pubs.acs.org/doi/10.1021/bi00811a001https://doi.org/10.1021/bi00811a001research-articleACS PublicationsRequest reuse permissionsArticle Views57Altmetric-Citations71LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Spin Diffusion in Pure Multiple-Pulse NQR (2000)

We present a detailed theoretical and experimental NQR multiple-pulse spin-locking study of spin-lattice relaxation and spin diffusion processes in the presence of paramagnetic impurities in solids. The obtained diffusion equation was obtained allows to find the time dependence of the magnetization in the effective field. The spin lattice relaxation times were calculated, both for direct and diffusion regimes, as functions of the correlation time and multiple-pulse parameters. Measurements of relaxation times in rotating frame allow to determine the diffusion coefficient and the radius of the diffusion barrier in γ-irradiated polycrystalline samples of NaCIO 3 .
STRESS STATE ANALYSIS OF SUB-SIZED PRE-CRACKED THREE-POINT-BEND SPECIMEN (2012)

The contribution deals with finite element analysis of stress state in sub-sized precracked three-point bend specimen (KLST). A studied material was Eurofer’97 steel. The true stress-true strain curve was obtained from tensile test. The three-point-bend tests were carried out on pre-cracked plain and side-grooved specimens at ambient temperature. Performed tests were simulated using FEA software ABAQUS 6.10. The stress state in KLST specimen was compared with the stress state of pre-cracked Charpy and 1T SENB. The analysis confirmed the stress state in KLST specimens at the crack tip does not correspond to the stress state of standard fracture toughness determination because loss of crack-tip and out-of-plane constraint.
Rapid indexable positioning system (RIPS) for 3D printed aerospace electro-optics (2022)

3D printing is a rapid manufacturing methodology which provides low turnaround times greatly advancing the efficacy of low technology readiness level (TRL) prototyping of opto-electric sensors. Herein, we describe the design and evaluation of a discrete adjustable optical prototyping system, refered to as the Rapid Indexable Positioning System which can be utilized in conjunction with formfitting 3D printed opto-mechanical components to aid in the development of aerospace payloads. “Grid holes” are integrated to an enclosure wall using a grid pattern of holes on every face of a payload enclosure. This works in conjunction with various components that can be semi-permanently positioned with the use of “studs,” allowing for rapid validation of layout within an enclosure. The demonstration of this technique is conducted on prints using both PLA and ABS with the use of a Raise3D Pro2 Printer with the print properties of 20% honeycomb infill and .2mm layer height. The use of this technique in payload enclosure development facilitates rapid and indexable changes to be made, requiring that only a single enclosure, which requires nearly 24 hours to print. This print can be utilized with multiple iterations of each part to be indexed, requiring only about 1 hour. Additional Dynamic oscillation simulations can be conducted to ensure that the optical components would remain within a necessary manifold of deflection once the viability of their final location was verified.
Switching Network Loss Minimization Through Multivariable Modulation in a Multiactive Bridge Converter (2022)

This article presents a unified and generalized modeling, circuit analysis, and power flow optimization techniques for an <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">n</i> -port multiactive bridge (MAB) dc–dc converter comprised of <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">n</i> active full bridges and a multiwinding transformer. The article aims at improving the efficiency of the MAB converter for a wide load and port voltage gain range by proposing an optimal phase-duty control variable-based modulation strategy. The loss optimization technique constitutes of two stages: first, both the switching and conduction loss objective functions are equivalently formulated by relating them to the transformer winding current peaks and rmss that are synthesized by employing the proposed generalized harmonic approximation based computational model; second, a multivariable multiconstrained optimization technique is adopted in order to minimize the converter power loss for wide load-gain range. Moreover, the universal zero-voltage switching criteria for any MAB port is also derived by proposing a port-equivalent converter model. A 600 W quadruple active bridge converter proof-of-concept is designed and tested to validate the theoretical analysis, claims, thus verifying the applicability of the generic MAB loss optimization technique for any converter candidate under the MAB family. With the implementation of proposed optimal phase-duty control, the experimental results show efficiency increment up to 17% at nonunity voltage gain and 10% loading condition, when compared to the conventional phase modulation technique.
Electrolytic anti-fouling in industrial and marine applications (1987)

It is well established that in both cold and warm sea water there can be rapid growth of large fouling organisms, which can be seen at low tides growing on jetties, platforms and rig legs etc.
Associated factors of poor treatment outcomes in patients with giant cell arteritis: clinical implication of large vessel lesions (2020)

The initial treatment intensity in the treatment algorithm of GCA could be determined based upon the presence or absence of LVLs detected by imaging at baseline.
Neutral point clamped quasi-impedance-source inverter (2011)

In this paper a new modification of a three-level neutral-point-clamped inverter is presented. The proposed topology combines the advantages of the three-level neutral-point-clamped full-bridge inverter with those of the quasi-impedance-source inverter. The neutral-point-clamped quasi-impedance-source inverter is especially suitable for renewable energy sources. The steady-state analysis of a neutral-point-clamped quasi-impedance-source inverter in the case of continuous conduction mode is presented. The presented models as well as deduced equations are verified in a simulation.
Coordination Structure of Titanium Ions in Molten LiF-KF Mixture with the Addition of TiO2 and Bulk Titanium (2022)

The difference between Ti(III) and Ti(IV) significantly influences the electrodeposition process of Ti in fluoride melt. In this study, we investigated the melt structure of LiF-KF with the addition of TiO 2 for Ti(IV) and with the addition of both TiO 2 and bulk titanium (Ti 0 ) for Ti(III) by combining high-temperature Raman spectroscopic technique and density functional theory calculations. The Raman spectra were characterized by three kinds of coordination structures: polyatomic ion-like structures such as TiO 2 F 2 2− , polyatomic cation-coordinated ion-like structures such as [TiF 6 −K] − , and molecule-like structures such as TiOF 3 −K. The results showed that the K + ions are more likely to form structures with the titanium oxyfluorides. We also found that the melt with and without Ti 0 showed almost completely different Raman bands. The information gained in this study for the coordination structure around titanium ions in the fluoride melts is significant towards the electrodeposition process of titanium-based materials in fluoride melt and marks an important step towards further understanding of the dissolution process of titanium oxyhalide structure in the melt.
Cement Mortars Modified by SB Latexes with Variable Bound Styrene (1964)

Abstract Recently, the practical research and development of SB latex for a cement modifier have taken place and the cement mortars so modified are used in the field of building or civil engineering. The physical and chemical properties of SB latex-modified mortars have already been reported, but the effects of various polymerization conditions for latex synthesis on properties of SB latex-modified mortars have hardly been noticed. The authors discuss the effects of polymerization conditions, in particular, styrene/butadiene monomer ratio on physical properties of SB latex-modified mortar and conclude that the physical properties such as strength, drying shrinkage, adhesion, abrasion and shock resistance, etc., of SB latex-modified mortars are affected more intensely by the variation of bound styrene contents than by the rubber-cement ratios.
The Message without the Medium: Unifying Modern Mes- saging Paradigms through the Semantic Web (2004)

Since its inception, the Internet has been a hotbed of successful communications channels, starting off with e-mail, Internet Relay Chat and Usenet newsgroups and more recently adding weblogs, instant messaging, and news feeds. These systems have been developed quite independently over the past half century and continue to be extended with new functionality that addresses the broadening needs of their users and supports the full range of semantic expression. Stepping back, however, we observe that having a variety of messaging frameworks creates significant problems for users when attempting to manage and collate messages on a single topic or context that may be discussed via multiple media. We posit that no message should be constrained in this way by its medium. As it is, messaging applications are slowly converging in their functionalities. We show that a unified approach to messaging can be achieved in a single step through appropriate use of the RDF, a Semantic Web technology, as a data model. We further exploit this data model to develop appropriate user interface elements that allow aggregation of messages across protocols, and discuss the benefits that arise from such a scenario.
Single- and Multiple-Dose Pharmacokinetics, Safety, and Tolerability of the Selective α7 Neuronal Nicotinic Receptor Agonist, ABT-107, in Healthy Human Volunteers (2010)

ABT-107 is a potent, selective α7 nicotinic receptor agonist under development for treatment of Alzheimer's disease and cognitive deficits associated with schizophrenia. The pharmacokinetics, safety, and tolerability of escalating single oral doses (1, 3, 10, 30, 60, 80, and 100 mg; double-blind, placebo-controlled, randomized, incomplete crossover design) and multiple oral doses (2, 6, and 15 mg once daily for 7 days; double-blind, placebo-controlled, randomized, parallel-group design) of ABT-107 were evaluated. Additionally, effect of food on ABT-107 pharmacokinetics (20-mg single dose) was evaluated using an open-label, 2-period, fasting and nonfasting, randomized, complete crossover design. ABT-107 exhibited nonlinear (more than dose-proportional) pharmacokinetics. ABT-107 half-life ranged from 7 to 10 hours, and steady state was achieved by day 6 of dosing. Food did not have a clinically meaningful effect on ABT-107 exposure. ABT-107 was safe and well tolerated over the tested dose range. The most frequently reported adverse events were nausea, headache, and tremor following single dosing and somnolence following multiple dosing. The pharmacokinetics, safety, and tolerability profiles of ABT-107 pose it as a good candidate for further development.