gebhart/patrepeval huggingface dataset:
Possible observation of a glassy ferroelectric:Bi1.8Pb0.3Sr2Ca2Cu2.8K0.2Oz (2000)

A glass sample of composition ${\mathrm{Bi}}_{1.8}{\mathrm{Pb}}_{0.3}{\mathrm{Sr}}_{2}{\mathrm{Ca}}_{2}{\mathrm{Cu}}_{2.8}{\mathrm{K}}_{0.2}{\mathrm{O}}_{z}$ was prepared by the conventional quenched-melt technique. The as-quenched sample has been confirmed to be amorphous by x-ray diffraction measurements. The scanning electron microscopy shows no sign of crystalline grain precipitation. Differential thermal analysis indicates a prominent endotherm at 530 K in addition to the glass transition at 607 K and crystallization at 717 K and melting at 1043 K. This extra endothermic peak could possibly be identified as due to a ferroelectric to paraelectric phase transition. This possibility was explored by performing electrical measurements, which include dielectric constant trace, polarization, and hysteresis loops measurements as a function of temperature. It was also found that the transition is irreversible if the glass-transition temperature was reached.
A mobile transaction processing system to improve concurrency in mobile database (2013)

Mobile Database System (MDS) is a distributed client/server system where clients can move around freely while performing their data processing activities in connected, disconnected, or intermittent connected mode [7]. It can process debit/credit transactions such as pay utility bills, airline reservations, and other transactions without being subject to any geographical constraints [8]. Since there is no MDS type of system available, it is difficult to identify the transaction volume at mobile units, however, the present information processing needs and trends in e-commerce indicate that transaction workload at each mobile unit could be high and MDS would be a useful resource to most of the organizations. Although MDS is a distributed system based on client/server paradigm [8], it differs from conventional centralized or distributed systems in transaction management schemes (concurrency control, database recovery, query processing, etc.), different logging scheme, different caching schemes, etc [8]. For example, in MDS or in any distributed system, a number of activities related to transactions' execution, such as transaction arrival at client or at a server, transaction fragmentation and their distribution to relevant nodes for execution, dispatch of updates made at clients to the server, migration of a mobile unit to another cell (handoff), etc., have to be logged for recovery.
La Biblia en la iconografía pétrea lucense: Ficha 27, el árbol de Jesé en el tímpano de la puerta de la Iglesia de Sta. María de Castelo, Taboada (2009)

We and other investigators have previously shown that membrane-type 1 matrix metalloproteinase (MT1-MMP) is overexpressed in invasive prostate cancer cells. However, the mechanism for this expression is not known. Here, we show that MT1-MMP is minimally expressed in nonmalignant primary prostate cells, moderately expressed in DU-145 cells, and highly expressed in invasive PC-3 and PC-3N cells. Using human MT1-MMP promoter reporter plasmids and mobility shift assays, we show that Sp1 regulates MT1-MMP expression in DU-145, PC-3, and PC-3N cells and in PC3-N cells using chromatin immunoprecipitation analysis and silencing RNA. Investigation of signaling pathway showed that DU-145 cells express constitutively phosphorylated extracellular stress-regulated kinase (ERK), whereas PC-3 and PC-3N cells express constitutively phosphorylated AKT/PKB and c-Jun NH2 terminal kinase (JNK). We show that MT1-MMP and Sp1 levels are decreased in PC-3 and PC-3N cells when phosphatidylinositol-3 kinase and JNK are inhibited, and that MT1-MMP levels are decreased in DU-145 cells when MEK is inhibited. Transient transfection of PC-3 and PC-3N cells with a dominant-negative JNK or p85, and of DU-145 cells with a dominant negative ERK, reduces MT1-MMP promoter activity. These results indicate differential signaling control of Sp1-mediated transcriptional regulation of MT1-MMP in prostate cancer cell lines.
Overt and occult hepatitis B among immigrants and native blood donors in Madrid, Spain (2020)

Active HBV infection is currently found in 0.022% of blood donations (0.038% of donors) in Madrid. This rate is 3-fold greater than for HIV and/or HCV. On the other hand, HBsAg+ donors are 3-fold more frequent than OBI donors and more often immigrants than native Spaniards. No transfusion-transmitted HBV infections were identified during the study period, including retrospective checking of former recipients of OBI donors.
Neuregulin 4 Downregulation Induces Insulin Resistance in 3T3-L1 Adipocytes through Inflammation and Autophagic Degradation of GLUT4 Vesicles (2021)

The adipokine Neuregulin 4 (Nrg4) protects against obesity-induced insulin resistance. Here, we analyze how the downregulation of Nrg4 influences insulin action and the underlying mechanisms in adipocytes. Validated shRNA lentiviral vectors were used to generate scramble (Scr) and Nrg4 knockdown (KD) 3T3-L1 adipocytes. Adipogenesis was unaffected in Nrg4 KD adipocytes, but there was a complete impairment of the insulin-induced 2-deoxyglucose uptake, which was likely the result of reduced insulin receptor and Glut4 protein. Downregulation of Nrg4 enhanced the expression of proinflammatory cytokines. Anti-inflammatory agents recovered the insulin receptor, but not Glut4, content. Proteins enriched in Glut4 storage vesicles such as the insulin-responsive aminopeptidase (IRAP) and Syntaxin-6 as well as TBC1D4, a protein involved in the intracellular retention of Glut4 vesicles, also decreased by Nrg4 KD. Insulin failed to reduce autophagy in Nrg4 KD adipocytes, observed by a minor effect on mTOR phosphorylation, at the time that proteins involved in autophagy such as LC3-II, Rab11, and Clathrin were markedly upregulated. The lysosomal activity inhibitor bafilomycin A1 restored Glut4, IRAP, Syntaxin-6, and TBC1D4 content to those found in control adipocytes. Our study reveals that Nrg4 preserves the insulin responsiveness by preventing inflammation and, in turn, benefits the insulin regulation of autophagy.
Gain measurements on semiconductor lasers by optical feedback from an external grating cavity (1983)

We report on new methods to determine the curvature around maximum of the mode gain curve of homogeneously line-broadened semiconductor lasers, either by measuring the wavelength dependence of threshold current of the laser coupled to an external grating cavity or by measuring the tuning range of the laser versus the amount of optical feedback. We experimentally found the mode gain width and the current-induced peak-gain wavelength shift of a GaAlAs CSP laser to 175 Å and 2.1 Å/ mA, respectively.
New two-dimensional porous graphitic carbon nitride nanosheets for highly efficient photocatalytic hydrogen evolution under visible-light irradiation (2018)

A one-step thermopolymerization method based on a supramolecular precursor has been developed for preparing 2D porous graphitic carbon nitride.
The bromodomain-containing protein Ibd1 links multiple chromatin-related protein complexes to highly expressed genes in Tetrahymena thermophila (2021)

Background: The chromatin remodelers of the SWI/SNF family are critical transcriptional regulators. Recognition of lysine acetylation through a bromodomain (BRD) component is key to SWI/SNF function; in most eukaryotes, this function is attributed to SNF2/Brg1. &lt;div&gt;Results: Using affinity purification coupled to mass spectrometry (AP–MS) we identified members of a SWI/SNF complex (SWI/SNFTt) in Tetrahymena thermophila. SWI/SNFTt is composed of 11 proteins, Snf5Tt, Swi1Tt, Swi3Tt, Snf12Tt, Brg1Tt, two proteins with potential chromatin-interacting domains and four proteins without orthologs to SWI/SNF proteins in yeast or mammals. SWI/SNFTt subunits localize exclusively to the transcriptionally active macronucleus during growth and development, consistent with a role in transcription. While Tetrahymena Brg1 does not contain a BRD, our AP–MS results identified a BRD-containing SWI/SNFTt component, Ibd1 that associates with SWI/SNFTt during growth but not development. AP–MS analysis of epitope-tagged Ibd1 revealed it to be a subunit of several additional protein complexes, including putative SWRTt, and SAGATt complexes as well as a putative H3K4-specific histone methyl transferase complex. Recombinant Ibd1 recognizes acetyl-lysine marks on histones correlated with active transcription. Consistent with our AP–MS and histone array data suggesting a role in regulation of gene expression, ChIP-Seq analysis of Ibd1 indicated that it primarily binds near promoters and within gene bodies of highly expressed genes during growth. &lt;div&gt;Conclusions: Our results suggest that through recognizing specific histones marks, Ibd1 targets active chromatin regions of highly expressed genes in Tetrahymena where it subsequently might coordinate the recruitment of several chromatin-remodeling complexes to regulate the transcriptional landscape of vegetatively growing Tetrahymena cells.&lt;/div&gt;&lt;/div&gt;
Response of the Termite, Coptotermes formosanus SHRIAKI to Extracts from Fungus-infected and Delignified Fungus-infected Woods (1976)

この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されました。
Kinetic and Reaction Engineering Studies of Dry Reforming of Methane over a Ni/La/Al2O3 Catalyst (1997)

Kinetic studies of CO2 reforming of methane over a highly active Ni/La/α-Al2O3 catalyst were performed in an atmospheric microcatalytic fixed-bed reactor. The reaction temperature was varied between 700 and 900 °C, while partial pressures of CO2 and CH4 ranged from 16 to 40 kPa. From these measurements kinetic parameters were determined; the activation energy amounted to 90 kJ/mol. The rate of CO2 reforming was described by applying a Langmuir−Hinshelwood rate equation. The developed kinetics was interpreted with a two-phase model of a fluidized bed. The predictions for a bubbling-bed reactor operated with an undiluted feed (CH4:CO2 = 1:1) at 800 °C showed that, on an industrial scale, significantly longer contact times (Hmf = 7.8 m, mcat/VSTP = 31.8 g·s·mL-1) are necessary for achieving thermodynamic equilibrium (XCH4 = 88.2%, XCO2 = 93.6%). The performance of the reactor was strongly influenced by the interphase gas exchange: the highest space time yields were obtained for small particles (dp = 80 μm).
Optimization of 3D autologous chondrocyte-seeded polyglycolic acid scaffolds to mimic human ear cartilage (2023)

Auricular reconstruction in children with microtia is one of the more complex procedures in plastic surgery. Obtaining sufficient native material to build an ear requires harvesting large fragments of rib cartilage in children. Herein, we investigated how to optimize autologous chondrocyte isolation, expansion and re-implantation using polyglycolic acid (PGA) scaffolds for generating enough cartilage to recapitulate a whole ear starting from a small ear biopsy. Ear chondrocytes isolated from human microtia subjects grew slower than microtia rib or healthy ear chondrocytes and displayed a phenotypic shift due to the passage number. Rabbit ear chondrocytes co-cultured with mesenchymal stem cells (MSC) at a 50 : 50 ratio recapitulated the cartilage biological properties <i>in vitro</i>. However, PGA scaffolds with different proportions of rabbit chondrocytes and MSC did not grow substantially in two months when subcutaneously implanted in immunosuppressed mice. In contrast, rabbit chondrocyte-seeded PGA scaffolds implanted in immunocompetent rabbits formed a cartilage 10 times larger than the original PGA scaffold. This cartilage mimicked the biofunctional and mechanical properties of an ear cartilage. These results indicate that autologous chondrocyte-seeded PGA scaffolds fabricated following our optimized procedure have immense potential as a solution for obtaining enough cartilage for auricular reconstruction and opens new avenues to redefine autologous cartilage replacement.
Selection, Fitness, and Control of Grape Isolates of Botrytis cinerea Variably Sensitive to Fenhexamid (2013)

Of 683 Botrytis cinerea isolates collected from a fungicide-trial vineyard, 31 were classified as putatively resistant to fenhexamid (50% effective concentration [EC<sub>50</sub>] ≥ 0.1 μg/ml). For the resistant isolates that survived and sporulated in culture, colony expansion and conidial germination frequency was significantly reduced relative to the mean of 30 representative baseline isolates (EC<sub>50</sub> = 0.03 μg/ml). Grape berries were inoculated with four isolates representing a range of fenhexamid sensitivities and treated preventively or curatively with fenhexamid concentrations (150 to 600 mg/liter) representing 25 to 100% of the recommended rate. All treatments significantly delayed disease onset and progress caused by isolates with EC<sub>50</sub> values of 0.03 and 0.15 μg/ml but provided little to no control of isolates with EC<sub>50</sub> values of 0.32 and 62.5 μg/ml. The latter isolate exhibited a previously unreported F427V mutation of ERG27, an enzyme of ergosterol biosynthesis. In a duplex quantitative polymerase chain reaction test, the ratio of pathogen/host DNA increased significantly for 14 days after inoculation of untreated berries with a baseline isolate but declined slightly in berries treated with fenhexamid at 600 mg/liter 1 day post inoculation. In the vineyard, disease control was affected by the number and rate of fenhexamid applications but B. cinerea isolates with EC<sub>50</sub> ≥ 0.1 μg/ml were not preferentially selected.
Diagnostic cellular organization features extracted from autofluorescence images (2007)

Depth-resolved NADH autofluorescence images are shown to differentiate between normal and precancerous engineered tissues. An inverse power law behavior of the power spectral density (PSD) of these images is observed, indicating a self-affine organization of mitochondrial NADH at length scales 1-10 microm. Power exponents of the PSD functions vary significantly with tissue depth and precancerous state, giving insight into the morphological changes associated with precancerous lesions and providing substantial potential for noninvasive clinical diagnosis of squamous epithelial lesions and tumors.
ChemInform Abstract: Generation and Trapping of Benzyl Radicals from Benzyl Iodides by Cobaloxime‐Mediated Iodine Atom Abstractions. (1993)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Characterization of MOVPE Grown GaAs<sub>1-x</sub>N<sub>x</sub>/GaAs Multiple Quantum Wells Emitting Around 1.3-&#x003BC;m-Wavelength Region (2007)

GaAs <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0.949</sub> N <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0.051</sub> /GaAs multiple quantum wells (MQWs) were grown on GaAs (001) substrates by metalorganic vapor phase epitaxy (MOVPE). Strong photoluminescence (PL) emission around the 1.3-μm-wavelength region was observed without post-growth thermal annealing, which suggests an efficient electron confinement in the GaAs <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0.949</sub> N <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0.051</sub> /GaAs MQWs. After post-growth thermal annealing, blue-shift of PL peak energy was clearly observed. This PL blue-shift, induced by thermal annealing, can be described by diffusion of N out of the quantum well and homogenization of the N concentration fluctuation. Furthermore, a reduction of PL full width at half maximum (FWHM) suggests the more homogeneous N distribution. In addition, both the as-grown and annealed GaAs <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0.949</sub> N <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0.051</sub> /GaAs MQWs exhibit fairly flat and abrupt GaAsN/GaAs interfaces, which were confirmed by high resolution X-ray diffraction (HRXRD) and transmission electron microscopy (TEM) measurements. Based on PL results, it is evident that the band alignment of GaAsN/GaAs hetero-structure is a type-I band lineup. Adding N to GaAs mainly affects the conduction band (CB) states leading to a large conduction band offset (ΔE <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">C</sub> ~ 550 meV). Our results show the potential for the fabrication of 1.3 μm GaAsN QW lasers on GaAs substrates.
ChemInform Abstract: SYNTHESIS AND CERTAIN PROPERTIES OF OLIGOESTER PEROXIDES (1978)

Abstract Oligoester‐peroxide (III), (V) und (VIII) lassen sich nach 3 Verfahren darstellen.
The Final Stages of Protein Synthesis and the Role of Lipids in the Process (1962)

Microbiology Society journals contain high-quality research papers and topical review articles. We are a not-for-profit publisher and we support and invest in the microbiology community, to the benefit of everyone. This supports our principal goal to develop, expand and strengthen the networks available to our members so that they can generate new knowledge about microbes and ensure that it is shared with other communities.
Structural determination of N‐linked glycans by matrix‐assisted laser desorption/ionization and electrospray ionization mass spectrometry (2005)

This paper reviews methods for the analysis of N-linked glycans by mass spectrometry with emphasis on studies conducted at the Oxford Glycobiology Institute. Topics covered are the release of glycans from sodium dodecyl sulphate-polyacrylamide gel electrophoresis gels, their purification for analysis by mass spectrometry, methods based on matrix-assisted laser desorption/ionization (MALDI) and electrospray ionization for producing fragment ions, and details of their fragmentation. MALDI mass spectrometry provided a rapid method for profiling neutral N-linked glycans as their [M + Na](+) ions which could be fragmented by collision-induced decomposition to give spectra containing both glycosidic and cross-ring fragments. Electrospray ionization mass spectrometry was more versatile in that it was relatively easy to change the type of ion that was formed and, furthermore, unlike MALDI, electrospray did not cause extensive loss of sialic acids from sialylated glycans. Negative ions formed by addition of anions such as chloride and, particularly, nitrate, to the electrospray solvent were stable and enabled singly charged ions to be obtained from larger glycans than was possible in positive ion mode. Fragmentation of negative ions followed specific pathways that defined structural details of the glycans that were difficult to obtain by classical methods such as exoglycosidase digestion.
Les opérations des sous-marins français et la perte du Protée (Méditerranée 1943) (1980)

Huan Claude. Les opérations des sous-marins français et la perte du Protée (Méditerranée 1943). In: Revue Historique des Armées, 7e année, numéro 4, 1980. pp. 127-146.
Geographical genotypes (geotypes) of poliovirus case isolates from the former Soviet Union: relatedness to other known poliovirus genotypes (1995)

A 150 nucleotide long region corresponding to adjoining segments of the genes encoding polypeptides VP1 and 2A of 84 poliovirus strains recently isolated from patients with paralytic poliomyelitis over the territory of the former Soviet Union (FSU) were characterized by sequencing and/or PCR amplification using specially designed primers. Eighteen isolates were found to be very closely related to one or another of the three Sabin vaccine strains. Three distinct classes of geographical genotypes (geotypes) were discerned among 42 wild-type (non-Sabin) strains of serotype 1. One such geotype (called A) was widely circulating in 1990–91 in the Caucasian (Azerbaijan and Georgia) as well as Asian (Kyrgyzstan and Turkmenistan) Republics; this geotype exhibited only weak relatedness to known strains isolated outside the FSU. On the other hand, a subset of strains belonging to another geotype (T) of serotype 1, which circulated in 1991 in Tajikistan, demonstrated very close relatedness to contemporaneous strains isolated in Pakistan, India and Jordan. Strains that were somewhat different, but belonging to the same T-geotype, were found also in Moldova and Georgia. Strikingly, the primary structure of the VP1/2A junction of certain T-geotype isolates differed from the corresponding region of Sabin 1 only in 13–15% of positions, thereby not reaching the upper limit accepted for a geotype. This observation raises, though does not prove, the possibility that at least the relevant segment of the T-geotype RNA originated from the vaccine strain. The third geotype of serotype 1 was represented by a single, perhaps imported, isolate. Four distinct subsets of a common geotype (C) were discerned among 24 wild-type isolates belonging to serotype 3. These strains exhibited a broad geographical distribution being found, in particular, in Armenia, Azerbaijan, Georgia, Turkmenistan and Tajikistan; on the other hand, the C-geotype strains exhibited only a relatively distant relatedness to a strain isolated outside of the FSU (in Oman).
Hardware for image processing and analysis: The PICAP approach (2005)

In image processing and analysis new parallel computer architectures have proved necessary since the classical sequential general propose computer often is to slow. The very large data volumes and the complexity of the processing make great demands on storage capability as well as processing power. The PICAP system of Linköping University has been designed to meet the demands in an interactive image processing environment. Being a multi-processor system it achieves its speed through global but also local parallelism. A virtual image memory alleviates the problem of storage space. An extensive menu-based command language makes interaction with the system a simple matter also for the less experienced user.
Suppression of Spinal Cord Motoneuron Excitability Correlates with Surgical Immobility during Isoflurane Anesthesia (1998)

The degree of H- and F-wave amplitude and F-wave persistence suppression correlates with movement response, suggesting that isoflurane-suppressive action in the spinal cord plays a significant role in producing surgical immobility.
<title>Development of a stereoscopic three-dimensional drawing application</title> (1991)

With recent advances in 3-D technology, computer users have the opportunity to work within a natural 3-D environment; a flat panel LCD computer display of this type, the DTI-100M made by Dimension Technologies, Inc., recently went on the market. In a joint venture between DTI and NCSU, an object-oriented 3-D drawing application, 3-D Draw, was developed to address some issues of human interface design for interactive stereo drawing applications. The focus of this paper is to determine some of the procedures a user would naturally expect to follow while working within a true 3-D environment. The paper discusses (1) the interface between the Macintosh II and DTI-100M during implementation of 3-D Draw, including stereo cursor development and presentation of current 2-D systems, with an additional `depth'' parameter, in the 3-D world, (2) problems in general for human interface into the 3-D environment, and (3) necessary functions and/or problems in developing future stereoscopic 3-D operating systems/tools.