1918 UPDATE ON THE PROSTATIC URETHRAL LIFT, A NOVEL MINIMALLY INVASIVE TREATMENT FOR SYMPTOMATIC BENIGN PROSTATIC HYPERPLASIA (2010)

You have accessJournal of UrologyBenign Prostatic Hyperplasia: Surgical Therapy and New Technology I1 Apr 20101918 UPDATE ON THE PROSTATIC URETHRAL LIFT, A NOVEL MINIMALLY INVASIVE TREATMENT FOR SYMPTOMATIC BENIGN PROSTATIC HYPERPLASIA Henry Woo, Peter Chin, Damien Bolton, Gregory Jack, Kevin Chu, Jeffrey Thavaseelan, Prem Rashid, Thomas McNicholas, Harcharan Gill, Mark Plante, Reginald Bruskewitz, and Claus Roehrborn Henry WooHenry Woo Sydney, Australia More articles by this author , Peter ChinPeter Chin Wollongong, Australia More articles by this author , Damien BoltonDamien Bolton Melbourne, Australia More articles by this author , Gregory JackGregory Jack Melbourne, Australia More articles by this author , Kevin ChuKevin Chu Melbourne, Australia More articles by this author , Jeffrey ThavaseelanJeffrey Thavaseelan Perth, Australia More articles by this author , Prem RashidPrem Rashid Port Macquarie, Australia More articles by this author , Thomas McNicholasThomas McNicholas Stevenage, United Kingdom More articles by this author , Harcharan GillHarcharan Gill Stanford, CA More articles by this author , Mark PlanteMark Plante Burlington, VT More articles by this author , Reginald BruskewitzReginald Bruskewitz Madison, WI More articles by this author , and Claus RoehrbornClaus Roehrborn Dallas, TX More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2010.02.1885AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES We previously reported on the first human experience with the Prostatic Urethral Lift, a tissue-sparing, minimally invasive method to treat symptomatic BPH and demonstrated the method is safe and feasible using early-generation devices. We now provide an update of our experience that includes use of a next-generation device under local anesthesia and expansion of the trial to multiple centers. METHODS A prospective cohort of 44 patients was treated with the Prostatic Urethral Lift at 5 centers (mean age 65; prostate volume: 21-149 cc). Custom sutures were placed transurethrally to separate the encroaching prostatic lobes and expand the urethral lumen. We assessed safety and feasibility by observation of adverse events and procedural completion rate. Effectiveness parameters included the International Prostate Symptom Score (IPSS), quality of life (QOL) score, and BPH Impact Index (BPH II). Flow, residual volume and sexual health parameters were also recorded. RESULTS Cases were completed successfully in all patients. 1 serious adverse event (overnight hospitalization to monitor urinary retention) was observed in over 43 patient-years of follow up. Thirteen recent patients were treated under local anesthesia with 7 of those patients undergoing an ultrasound guided peri-prostatic block and 6 receiving topical urethral analgesia, intravesical lidocaine and intravenous sedation. The procedure was well-tolerated under both local anesthesia protocols. As with the earlier cohort, considerable improvement from baseline was evidenced at the 2 week follow-up. We show sustained improvement through 2 years of follow-up within the first group of patients treated. Normal sexual function was maintained with no incidence of retrograde ejaculation. CONCLUSIONS We confirm our previous findings that the Prostatic Urethral Lift is a safe and feasible treatment for symptomatic BPH that appears to preserve sexual function with low morbidity. The next-generation device facilitated treatment under local anesthesia. The method is straightforward and readily performed by new investigators. The data continue to suggest a favorable effectiveness profile. © 2010 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 183Issue 4SApril 2010Page: e746 Advertisement Copyright & Permissions© 2010 by American Urological Association Education and Research, Inc.MetricsAuthor Information Henry Woo Sydney, Australia More articles by this author Peter Chin Wollongong, Australia More articles by this author Damien Bolton Melbourne, Australia More articles by this author Gregory Jack Melbourne, Australia More articles by this author Kevin Chu Melbourne, Australia More articles by this author Jeffrey Thavaseelan Perth, Australia More articles by this author Prem Rashid Port Macquarie, Australia More articles by this author Thomas McNicholas Stevenage, United Kingdom More articles by this author Harcharan Gill Stanford, CA More articles by this author Mark Plante Burlington, VT More articles by this author Reginald Bruskewitz Madison, WI More articles by this author Claus Roehrborn Dallas, TX More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...