gebhart/patrepeval huggingface dataset:
Derivatives of 2‐oxo‐3(2H)‐benzothiazolineacetonitrile and related compounds. II. Synthesis of 2‐oxo‐alkyl esters of 3(2H)‐benzothiazolineacetimidic acids and related products (1988)

Abstract The reaction of the appropriate 2‐benzothiazolinone or 2‐benzoxazolinone under basic conditions with (1) 2‐chloropropionitrile, (2) acrylonitrile, (3) 4‐chlorobutyronitrile or (4) chloroacetonitrile afforded the nitriles 1–8 . The reaction of various nitriles with alcoholic‐hydrogen chloride solutions at low temperatures afforded the hydrogen chloride salts of the imino‐ester which upon neutralization with potassium carbonate yielded the titled compounds.
Using individuality to track individuals: Clustering individual trajectories in crowds using local appearance and frequency trait (2009)

In this work, we propose a method for tracking individuals in crowds. Our method is based on a trajectory-based clustering approach that groups trajectories of image features that belong to the same person. The key novelty of our method is to make use of a person's individuality, that is, the gait features and the temporal consistency of local appearance to track each individual in a crowd. Gait features in the frequency domain have been shown to be an effective biometric cue in discriminating between individuals, and our method uses such features for tracking people in crowds for the first time. Unlike existing trajectory-based tracking methods, our method evaluates the dissimilarity of trajectories with respect to a group of three adjacent trajectories. In this way, we incorporate the temporal consistency of local patch appearance to differentiate trajectories of multiple people moving in close proximity. Our experiments show that the use of gait features and the temporal consistency of local appearance contributes to significant performance improvement in tracking people in crowded scenes.
Phase Transitions of Liquid Crystalline Polyacrylamide (1993)

Abstract The liquid crystalline polyacrylamides (PAAD-R) having secondary or tertiary amide groups were synthesized and the thermal properties of PAAD-R were studied. PAAD-H with the secondary amide group exhibited enantiotropically smectic phases with enhanced thermal stability through the formation of hydrogen bonding between amide groups when compared to PAAD-M with the tertiary amide group. Also, a liquid crystalline polyacrylate, which has the same mesogenic side chain as PAAD-H, was prepared and the thermal properties of PAAD-H and PA were compared.
1996 New York (2018)

Experiential realities of downsizing, reductions in force, restructuring, outsourcing, and cognate terms are often at wide variance with their touted and expected promises of increased productivity, profit, rationality, realism, efficiency, teamwork, and role interchangeability. Vignettes cited suggest that downsizing is not primarily about economics or business but, instead, myth and ritual. Downsizing is explored as a symbolic form and action, rationalized and masked by euphemism. Downsizing implements devastating planned social change, one that takes the form of sacrifice to purchase organizational life via symbolic death. Downsizing is experienced as a metaphoric Holocaust, one driven by the need to perform sacrifice (a) to separate bad from good parts of oneself and (b) to secure organizational rebirth through the expulsion of death. The link between the popular 1993 movie Schindler’s List and organizational themes in the language of 124the Holocaust is explored and takes us to the heart of the conscious and unconscious emotional experience and meaning of downsizing.
ISO/IEC 27001 – Spezifikationen und Mindestanforderungen (2022)

No AccessPraxisbuch ISO/IEC 27001Oct 2022ISO/IEC 27001 – Spezifikationen und MindestanforderungenMichael Brenner, Nils gentschen Felde, Wolfgang Hommel, Stefan Metzger, Helmut Reiser, Thomas SchaafMichael Brenner, Nils gentschen Felde, Wolfgang Hommel, Stefan Metzger, Helmut Reiser, Thomas Schaafhttps://doi.org/10.3139/9783446474581.004SectionsAboutPDF ToolsAdd to FavoritesDownload CitationTrack CitationsCopy LTI LinkPDF key 'share (en)' returned an object instead of string.FacebookTwitterEmailLinkedIn previous chapternext chapter FiguresReferencesRelatedDetails 2022Pages: 35-71Print ISBN: 978-3-446-47395-9eISBN: 978-3-446-47458-1 Copyright & Permissions© 2022 Carl Hanser Verlag GmbH & Co. KGPDF downloadLoading ...
Switching on stray electric fields in ferroelectric liquid crystal cells (1994)

Abstract In liquid crystal dot-matrix displays light may leak through the display area between the pixels. To obtain sufficient contrast this non-pixel area has to be made non-transmissive. For ferroelectric liquid crystal (FLC) displays this may be done by switching the material in the gaps between the picture elements to a non-transmissive state by the stray electric fields that occur during application of voltages to the pixel electrodes. This is experimentally studied for test cells with an electrically modified smectic layer structure. The gap region considered is an asymmetric environment of the FLC material, as the transparent conductive coating has been removed on one substrate, whereas on the other substrate a conductor covers the glass. The FLC molecules in the non-pixel area prefer to direct their dipoles towards the covered substrate. To switch the FLC material with the stray electric fields, it is a prerequisite to outweigh this preference. We made spatially resolved observations for various gap widths and various applied voltages on 2 μm thick FLC layers. With bipolar voltage pulses of 64 μs width each, amplitudes of about 25 V are needed to switch the FLC in 3·2 or 4·0 μm wide gaps. It was found to be more difficult to switch gaps that, are 7 μm wide than was anticipated on the basis of the results for 4 μm gaps. This is attributed to the surface polarization charge due to the FLC permanent dipoles built up at the FLC-glass interface. Experimental results supporting this explanation are presented.
Assembly of Graphene Oxide Nanosheets on Diamine-Treated PVDF Hollow Fiber as Nanofiltration Membranes (2020)

A graphene oxide (GO)-based nanofiltration membrane was fabricated on ethylenediamine-functionalized-polyvinylidene fluoride (EDA-PVDF) hollow fibers. EDA-PVDF was prepared by hydrothermal treatment of polyvinylidene fluoride (PVDF) with ethylenediamine (EDA). On the basis of the interaction of oxygen-containing functional groups of GO and amine groups of EDA-PVDF fiber, a uniform GO layer can be formed in a few seconds by simple immersion of the EDA-cross-linked PVDF fiber in a GO aqueous solution. The GO layer thickness can be controlled from ∼20 nm to several micrometers depending on the concentration of the GO solution (0.5 – 20 mg/mL). The GO layer is shown to be stable in water. The stability is attributed to the EDA in the EDA-PVDF fiber not only forming cross-links between GO and PVDF but also diffusing into the GO interlayer. Filtration tests with dye solutions show that the GO-EDA-PVDF fiber membrane can reject molecules with hydration radii larger than 8 Å (brilliant blue) with rejections (percentage of solute concentration of permeate removed from feed solution by the membrane) of over 95%. Finally, the stable performance of the GO-EDA-PVDF membrane is confirmed by practical crossflow filtration.
Smoking cessation during substance abuse rehabilitation (2019)

DiBaise, Michelle DHSc, PA-C, DFAAPA; Kempton, Danielle DHSc, MMS, PA-C; Shapiro, Julietta MPAS, PA-C; Frederick, Brooklynne MPAS, PA-C; Maison, Amber MPAS, PA-C; Bere, Melissa MPAS, PA-C; Shelton, Ryan MPAS, PA-C Author Information
<title>Linear-wedge spectrometer</title> (1990)

The wedge spectrometer design concept incorporates a tapered multilayer thin-film dielectric interference filter mounted in close proximity to a two-dimensional detector array such that each row of detectors receives energy from a different spectral band corresponding to the filter's bandpass at that position. This design concept is applicable to a broad range of spectral regimes, from the visible and near infrared through the longwave IR. Spectrometer design alternatives, performance characteristics, and development status are discussed.
Moving Beyond "Slaves, Sinners, and Saviors": An Intersectional Feminist Analysis of US Sex-Trafficking Discourses, Law and Policy (2013)

This article analyzes stories and images of sex trafficking in current mainstream US public discourses, including government publications, NGO materials, news media, and popular films. Noting the similarities and differences among these discourses, the first part demonstrates that they often frame sex trafficking using a rescue narrative that reiterates traditional beliefs and values regarding gender, sexuality, and nationality, relying heavily on patriarchal and orientalist tropes. Reflecting this rescue narrative, mainstream public policies focus on criminal justice solutions to trafficking. The second part suggests alternative frameworks that empower rather than rescue trafficked people. The article argues that the dominant criminal justice approach to trafficking—the state rescuing victims and prosecuting traffickers—will not alone end the problem of sex trafficking, but that public policies must address the structural conditions that create populations vulnerable to trafficking and empower those communities to dismantle inequalities that are the root causes of trafficking.
Analgesics and NSAIDs in the treatment of the acute migraine attack (1995)

In the treatment of migraine attacks, an antiemetic in combination with an analgesic or ergot alkaloid is widely recommended. Medication should be introduced as early as possible, but only when there is no doubt that the headache is due to migraine. The antiemetic provides relief from the nausea and vomiting and also enhances the resorption of analgesics or ergot preparations. Domperidone 20 mg orally and 20 mg metoclopramide as suppository or 10-20 mg orally are mostly used as antiemetics. Analgesics such as 1000 mg acetylsalicylic acid as effervescent tablets, or 1000 mg paracetamol as effervescent tablets or suppositories should be given 15-20 min later. If this treatment fails, NSAIDs can be tried. In some studies naproxen in doses between 500 and 1000 mg and ibuprofen in doses between 400 and 800 mg have been shown to be effective, as well as NSAIDs like diclofenac, mefenamic acid, ketoprofen, tolfenamic acid and pirprofen. NSAIDs have been found to be superior to placebo and to standard reference drugs in the majority of the reviewed double-blind trials. Nevertheless, these effects are marginal in some studies or even without clinical relevance. Accordingly, there is still a need for further comparative studies.
SEL1L–HRD1 endoplasmic reticulum-associated degradation controls STING-mediated innate immunity by limiting the size of the activable STING pool (2023)

Stimulator of interferon genes (STING) orchestrates the production of proinflammatory cytokines in response to cytosolic double-stranded DNA; however, the pathophysiological significance and molecular mechanism underlying the folding and maturation of nascent STING protein at the endoplasmic reticulum (ER) remain unknown. Here we report that the SEL1L-HRD1 protein complex-the most conserved branch of ER-associated degradation (ERAD)-is a negative regulator of the STING innate immunity by ubiquitinating and targeting nascent STING protein for proteasomal degradation in the basal state. SEL1L or HRD1 deficiency in macrophages specifically amplifies STING signalling and immunity against viral infection and tumour growth. Mechanistically, nascent STING protein is a bona fide substrate of SEL1L-HRD1 in the basal state, uncoupled from ER stress or its sensor inositol-requiring enzyme 1α. Hence, our study not only establishes a key role of SEL1L-HRD1 ERAD in innate immunity by limiting the size of the activable STING pool, but identifies a regulatory mechanism and therapeutic approach to targeting STING.
논문 : 작잠 실크 피브로인에 의한 in vitro 상처 회복 효과 및 에탄올 처리에 따른 작잠 실크 피브로인 스폰지의 구조 전이 (2014)

작잠 누에고치를 정련한 후 질산칼슘4수화물의 용융액을 사용하여 재생 작잠 실크피브로인 스펀지를 제조하였다. 작잠 실크피브로인은 280 nm에서 tyrosine 잔기 등에 기인한 흡광대를 나타내었다. 작잠 실크피브로인 스펀지를 에탄올 농도별로 처리한 후 구조 전이를 관찰한 결과 80%에탄올 처리시에는 β-sheet 구조(700 cm-1), α-helix 구조 (625 cm-1), 그리고 random coil (660 cm-1) 구조가 공존하는 것으로 나타났다. 또한 작잠 실크피브로인을 이용한 in vitro 상처회복실험 결과 실크피브로인의 첨가에 의하여 상처회복 효과가 인정되었다.
Thermally activated magnesium oxide as a selective deuteration catalyst under mild conditions (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThermally activated magnesium oxide as a selective deuteration catalyst under mild conditionsM. Fazlul. Hoq and Kenneth J. KlabundeCite this: J. Am. Chem. Soc. 1986, 108, 8, 2114–2116Publication Date (Print):April 1, 1986Publication History Published online1 May 2002Published inissue 1 April 1986https://pubs.acs.org/doi/10.1021/ja00268a076https://doi.org/10.1021/ja00268a076research-articleACS PublicationsRequest reuse permissionsArticle Views283Altmetric-Citations19LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Temperature modulated excitation and phase sensitive detection to selectively image DNA sequences (2011)

Temperature oscillations allow one to modulate the concentration of reagents and products with given amplitude and phase shift, both parameters depending on the dynamics of the chemical system under study. We here rely on thermal excitation in a microdevice, associated with fluorescence video microscopy as well as image filtering protocols, to selectively enhance the signal issued from a labeled probe that hybridizes with a targeted oligonucleotide. Furthermore, by simply tuning the stimulation parameters, focus can be put either on the perfect match sequence or on some other one that bears a point mutation.
The Role of the Supraspinatus and Infraspinatus Muscles in Glenohumeral Kinematics of Anterior Shoulder Instability (1991)

To investigate a socket mechanism responsible for controlling the kinematics in the statically positioned glenohumeral joint, a suprascapular nerve block was performed in 13 selected patients, with recurrent anterior instability and defects of the labrum. Kinematics were then documented by roentgenograms in four positions within the horizontal motion plane. Combined paralysis of the supraspinatus and infraspinatus muscles resulted in abnormal anterior translation in only two of 47 roentgenograms. Normal ball-and-socket kinematics were retained in the remaining 45 roentgenograms. The consistent arthroscopic findings were an undamaged glenoid articular surface with a detached or absent labrum. The injury to the labrum reduced the depth of the socket by one-half. The other one-half of the socket provided by the contour of the glenoid remained intact. A balanced muscle envelope was not required to maintain normal kinematics in selected, actively positioned, unstable shoulders. The retained glenoid depth was sufficient to produce the observed ball-and-socket kinematics. Further in vivo study of shoulder kinematics will be needed to clarify the interactive roles of the socket and muscle envelope in maintaining glenohumeral stability during the more demanding stresses during active shoulder motion.
Changes in Aerobic Capacity and Visceral Fat but not Myocyte Lipid Levels Predict Increased Insulin Action After Exercise in Overweight and Obese Men (2003)

These results suggest that in overweight and obese sedentary men, increase in insulin sensitivity with moderate intensity exercise is predicted by improvement in aerobic capacity and reduction in visceral fat but is independent of myocyte triglyceride or LCAC levels.
The Jorge Luis Borges Collection at the University of Texas at Austin (2001)

Abstract This research note reports on a collection of manuscript and print materials relating to Argentine writer Jorge Luis Borges (1899–1986). The collection was acquired in 1999 by the Harry Ransom Humanities Research Center at the University of Texas at Austin. It features unpublished manuscripts in a variety of literary genres and an excellent representation of Borges's published works, including several rare books and periodicals from the 1920s, a period of increasing importance in Borges scholarship.
The Effect of Very High Interval Training on the Carnosine Content and Buffering Capacity of V Lateralis from humans (2007)

Carnosine (Carn) occurs in high concentrations in muscle where it contributes to H+ buffering. While Carn is increased in chronically trained athletes, the effects of acute training are less clear....
Ultrafast light-controlled optical-fiber modulator (1987)

We report the ultrafast operation of a light-controlled optical-fiber modulator, driven by subpicosecond, compressed, and amplified (6000 Å) dye laser pulses, controlling frequency-doubled (5320 Å) yttrium aluminum garnet laser pulses. The operation of the modulator is based on the optical Kerr effect, and its main component is 7 mm of single-mode optical fiber. Using this system as a light-controlled shutter, we produced either 0.4 ps green light pulses or 0.5 ps holes on the much longer duration second harmonic pulses.
Carbon-Based Nanomaterials: Multifunctional Materials for Biomedical Engineering (2013)

Functional carbon-based nanomaterials (CBNs) have become important due to their unique combinations of chemical and physical properties (i.e., thermal and electrical conductivity, high mechanical strength, and optical properties), and extensive research efforts are being made to utilize these materials for various industrial applications, such as high-strength materials and electronics. These advantageous properties of CBNs are also actively investigated in several areas of biomedical engineering. This Perspective highlights different types of carbon-based nanomaterials currently used in biomedical applications.
Polymere mit dem zentralatom eines makrocyclus in der hauptkette, 3.Polykondensationsreaktionen mit zinnkomplexen des meso‐tetraphenylporphins, phthalocyanins und hemiporphyrazins (1975)

Abstract Dihydroxy‐ meso ‐tetraphenylporphinzinn ( 1b ), Dihydroxyphthalocyaninzinn ( 1d ) und Dihydroxyhemiporphyrazinzinn ( 1f ) reagieren mit zweiwertigen Phenolen zu Polymeren des Typs B . Aus Äthylenglykol und 1b läßt sich die niedermolekulare Verbindung 3 erhalten, die unter Äthylenglykolabspaltung Poly[oxyäthylenoxy( meso ‐tetraphenylporphin)stannandiyl] ( 4 ) ergibt. Durch Dehydratation der Dihydroxy‐Verbindungen 1b, 1d, 1f lassen sich Polymere des Typs C synthetisieren. Die IR‐Spektren der dargestellten Verbindungen werden diskutiert; thermogravimetrische und Halbleitermessungen (σ 298K ≈10 −6 −10 −16 Ω −1 cm −1 ) werden beschrieben und mit den analogen Germaniumverbindungen verglichen.
Extending Security-by-Contract with Quantitative Trust on Mobile Devices (2010)

Security-by-Contract (S×C) is a paradigm providing security assurances for mobile applications. In this work, we present an extension of S×C enriched with an automatic trust management infrastructure. Indeed, we enhance the already existing architecture by adding new modules and configurations for contracts managing. At deploy-time, our system decides the run-time configuration depending on the credentials of contract provider. Roughly, the run-time environment can both enforce a security policy and monitor the declared contract. According to the actual behaviour of the running program our architecture updates the trust level associated with the contract provider. The main advantage of this method is an automatic management of the level of trust of software and contract releasers.
Use of an Alternative Colorant for Polyethylene Fuel Tanks Recycling (2002)

A black colorant alternative to carbon black, for Polyethylene tanks, which avoids the hysteresis of solvent and allows a more friendly recycling process, was studied. Sorption-desorption isotherms where obtained using a model molecule (n-heptane), in order to simulate the contact with the fuel. The material pigmented with the alternative black colorant was put in contact with liquid fuel for six months: after desorption the rheological behaviour was analyzed at 240°C. Films were obtained after contact with fuel, and submitted to dynamic mechanical analysis. The experimental data were compared with the ones obtained from the material utilized by FIAT Company (Italy) for fuel tanks (carbon black pigmented), both virgin and used ones.
Inhibition of the Inflammatory Pathway Enhances Both the <i>in Vitro</i> and <i>in Vivo</i> Transfection Activity of Exogenous <i>in Vitro</i>-Transcribed mRNAs Delivered by Lipid Nanoparticles (2019)

While the use of in vitro-transcribed mRNA (IVT-mRNA) in therapeutics is a rapidly expanding area, the transfection of the exogenous IVT-mRNA is accompanied by a risk of immune activation. This immunological defense mechanism suppresses cellular translation process and can reduce transfection efficiency to a considerable extent. In the present study, we investigated the in vitro effects of Integrated Stress Response Inhibitor (ISRIB), and dexamethasone, a steroidal anti-inflammatory drug, on the transfection activity of a lipid nanoparticle (LNP) that was composed of ionizable lipids and IVT-mRNA. In the case of transfection to mouse embryonic fibroblast (MEF) cells, ISRIB mainly enhanced the transfection activity at an early stage of transfection (0-6 h). In contrast, dexamethasone caused an increase in transfection activity at intermediate-late stages of transfection (4-48 h). We also investigated the in vivo effects of dexamethasone using an LNP on that the IVT-mRNA and lipid-conjugated dexamethasone (Dex-Pal) were co-loaded. The intravenous administration of the LNP successfully enhanced the protein expression in a mouse liver by up to 6.6-fold. Collectively, the co-delivery of an anti-inflammatory drug is a promising approach for enhancing transfection efficiency of IVT-mRNA.
Mechanism of red cell 2,3-diphosphoglycerate increase in neonatal lambs (1983)

The tenfold increase in red cell 2,3-diphosphoglycerate (DPG) concentration that occurs during the first 5 days of life in lambs is an important adaptation to extrauterine life. In lambs, DPG reduces hemoglobin oxygen affinity by the Bohr effect. Our data on 10 neonatal lambs suggest that the biochemical mechanism underlying this DPG increase involves the following: (1) a rise in plasma glucose from 40 to 100 mg/dl in the first 48 hr of life, which allows for increased glucose consumption in the highly glucose-permeable neonatal RBC; (2) a transitory rise in blood pH begins at birth, peaks at about 20 hr, and falls slightly; (3) the pH increase coincides with a threefold increase in RBC fructose-1,6-diphosphate (FDP) concentration due, we believe, to pH activation of phosphofructokinase; (4) glycolytic intermediates after the glyceraldehyde-3-phosphate dehydrogenase (GAPD) step do not rise in the first 24 hr of life, possibly due to insufficient inorganic phosphate (Pi), a substrate of GAPD; (5) plasma Pi increases from about 7 mg/dl at birth to 11 mg/dl at 72 hr, activates the GAPD, and FDP levels decline; and (6) the in vitro activity of the DPG synthetic enzyme, DPG mutase, is increased 12-fold in neonatal compared to adult RBC. We conclude that the postnatal rise in DPG is explained at least in part by the sequential effects of these metabolic changes.