gebhart/patrepeval huggingface dataset:
PRIVED: a Privacy Model for Heterogeneous Mobile Networks (2011)

We propose a network-oriented privacy model (PRIVED) composed by a well deﬁned information model, using events, information sets and relationships to deﬁne the conceptual privacy relationships that can occur in the network. We propose formal rules and a network instantiation, using linkability and correlation as the main tools for network applicability. We also use the model to determine the best approaches towards privacy protection in the network, resulting in a vertical/horizontal network privacy dichotomy.
Computational Model of Forward and Opposed Smoldering Combustion with Improved Chemical Kinetics (PhD. Thesis) (2005)

A computational study has been carried out to investigate smoldering ignition and propagation in polyurethane foam. The one-dimensional, transient, governing equations for smoldering combustion in a porous fuel are solved accounting for improved solid-phase chemical kinetics. A systematic methodology for the determination of solid-phase kinetics suitable for numerical models has been developed and applied to the simulation of smoldering combustion. This methodology consists in the correlation of a mathematical representation of a reaction mechanism with data from previous thermogravimetric experiments. Genetic-algorithm and trail-and-error techniques are used as the optimization procedure. The corresponding kinetic parameters for two different mechanisms of polyurethane foam smoldering kinetics are quantified: a previously proposed 3-step mechanism and a new 5-step mechanism. These kinetic mechanisms are used to model one-dimensional smoldering combustion, numerically solving for the solid-phase and gas-phase conservation equations in microgravity with a forced flow of oxidizer gas. The results from previously conducted microgravity experiments with flexible polyurethane foam are used for calibration and testing of the model predictive capabilities. Both forward and opposed smoldering configurations are examined. The model describes well both opposed and forward propagation. Specifically, the model predicts the reaction-front thermal and species structure, the onset of smoldering ignition, and the propagation rate. The model results reproduce the most important features of the smolder process and represent a significant step forward in smoldering combustion modeling.
Gene expression predicts overall survival in paraffin-embedded tissues of diffuse large B-cell lymphoma treated with R-CHOP (2008)

Gene expression profiling (GEP) on frozen tissues has identified genes predicting outcome in patients with diffuse large B-cell lymphoma (DLBCL). Confirmation of results in current patients is limited by availability of frozen samples and addition of monoclonal antibodies to treatment regimens. We used a quantitative nuclease protection assay (qNPA) to analyze formalin-fixed, paraffin-embedded tissue blocks for 36 previously identified genes (N = 209, 93 chemotherapy; 116 rituximab + chemotherapy). By qNPA, 208 cases were successfully analyzed (99.5%). In addition, 15 of 36 and 11 of 36 genes, representing each functional group previously identified by GEP, were associated with survival (P < .05) in the 2 treatment groups, respectively. In addition, 30 of 36 hazard ratios of death trended in the same direction versus the original studies. Multivariate and variable cut-off point analysis identified low levels of HLA-DRB (< 20%) and high levels of MYC (> 80%) as independent indicators of survival, together distinguishing cases with the worst prognosis. Our results solve a clinical research problem by demonstrating that prognostic genes can be meaningfully quantified using qNPA technology on formalin-fixed, paraffin-embedded tissues; previous GEP findings in DLBCL are relevant with current treatments; and 2 genes, representing immune escape and proliferation, are the common features of the most aggressive DLBCL.
ChemInform Abstract: IMIDAZOLE‐4,5‐DICARBOXYLIC ACID DERIVATES. PART II. 2,2′‐OLIGOMETHYLENE‐BRIDGED BISIMIDAZOLE‐4,5‐DICARBOXYLIC ACIDS (1976)

Abstract Aus den Benzimidazolen (I) werden durch Oxidation mit Perhydrol in schwefelsaurer Lösung die Dicarbonsäuren (II) dargestellt.
Recognizing multistroke geometric shapes (1993)

Article Free Access Share on Recognizing multistroke geometric shapes: an experimental evaluation Authors: Ajay Apte Laboratory for Pen-Based Silicon Paper Technology (PenLab), Department of Computer Science, Washington University, St. Louis, MO Laboratory for Pen-Based Silicon Paper Technology (PenLab), Department of Computer Science, Washington University, St. Louis, MOView Profile , Van Vo Laboratory for Pen-Based Silicon Paper Technology (PenLab), Department of Computer Science, Washington University, St. Louis, MO Laboratory for Pen-Based Silicon Paper Technology (PenLab), Department of Computer Science, Washington University, St. Louis, MOView Profile , Takayuki Dan Kimura Laboratory for Pen-Based Silicon Paper Technology (PenLab), Department of Computer Science, Washington University, St. Louis, MO Laboratory for Pen-Based Silicon Paper Technology (PenLab), Department of Computer Science, Washington University, St. Louis, MOView Profile Authors Info & Claims UIST '93: Proceedings of the 6th annual ACM symposium on User interface software and technologyDecember 1993 Pages 121–128https://doi.org/10.1145/168642.168654Published:01 December 1993Publication History 49citation951DownloadsMetricsTotal Citations49Total Downloads951Last 12 Months53Last 6 weeks7 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Seizure-like phenomena and propofol (2002)

Data on seizure-like phenomena (SLP) in patients receiving propofol were systematically reviewed. Reports had to provide detailed information on SLP in individual patients who received propofol. Phenomena were classified according to the time point of their occurrence during anesthesia or sedation (induction, maintenance, emergence, delayed [>30 minutes after emergence]) and their clinical presentation (generalized tonic-clonic seizures, focal motor seizures, events presented as increased tone with twitching and rhythmic movements not perceived as generalized tonic-clonic seizures, opisthotonos, involuntary movements). In 70 patients without epilepsy, SLP happened during induction in 24 (34%), during maintenance in two (3%), during emergence in 28 (40%), and was delayed in 16 (23%). Most frequent clinical presentations of SLP were generalized tonic-clonic seizures in 30 patients (43%), events presented as increased tone with twitching and rhythmic movements not perceived as generalized tonic-clonic seizures in 20 (36%), and involuntary movements in 11 (16%). Of 11 patients with epilepsy, seven (64%) had generalized tonic-clonic seizure during emergence. Of all 81 patients, 26 (32%) only had an EEG, and 12 (15%) only a neurologic consultation. SLP may happen in patients with or without epilepsy receiving propofol. The time point of the occurrence of SLP suggests that a change in cerebral concentration of propofol may be causal. To confirm this hypothesis, to estimate the prevalence of propofol-related SLP, and to identify patients at risk, data of higher quality are needed.
Quantitation of Aging Products Formed in Biodiesel during the Rancimat Accelerated Oxidation Test (2014)

Biodiesel (rapeseed oil methyl ester) was aged in a Rancimat device at a temperature of 110 °C and an air flow of 10 L/h. Time-resolved analyses applying gas chromatography–flame ionization detection, gas chromatography–mass spectrometry, and ion-exchange chromatography on the formation of aging products were performed. Formic and acetic acid, fatty acids with chain lengths from 5 to 18 carbon atoms, fatty acid methyl esters, and epoxides were quantified. After 12 h of aging, the concentrations of formic and acetic acid were 5600 ± 80 and 1360 ± 80 mg/kg, respectively. Fatty acid concentrations were in the range of <18–4200 mg/kg after 18 h of aging. Linoleic acid methyl ester and linolenic acid methyl ester (19 and 9.1 mass % of the non-aged fuel) were shown to be fully decomposed after 24 and 18 h of aging, respectively. After 51 h of aging, the concentration of oleic acid methyl ester (63 mass % of the non-aged fuel) decreased to 2.2 mass % and trans-epoxy stearic acid methyl ester and cis-epoxy stearic acid methyl ester reached concetrations of 5.9 and 0.7 mass %, respectively. The fuel composition shows only minor changes in early stages of aging, and a strong timely correlation of the formation of aging products with the end of the induction period of fuel was observed.
The metabolism of phytanic acid and pristanic acid in man: A review (1998)

The branched-chain fatty acid phytanic acid is a constituent of the diet, present in diary products, meat and fish. Degradation of this fatty acid in the human body is preceded by activation to phytanoyl-CoA and starts with one cycle of alpha-oxidation. Intermediates in this pathway are 2-hydroxy-phytanoyl-CoA and pristanal; the product is pristanic acid. After activation, pristanic acid is degraded by peroxisomal beta-oxidation. Several disorders have been described in which phytanic acid accumulates, in some cases in combination with pristanic acid. In classical Refsum disease, the enzyme that converts phytanoyl-CoA into 2-hydroxyphytanoyl-CoA--phytanoyl-CoA hydroxylase--is deficient, resulting in highly elevated levels of phytanic acid in blood and tissues. Also in rhizomelic chondrodysplasia punctata, phytanic acid accumulates, owing to a deficiency in the peroxisomal import of proteins with a peroxisomal targeting sequence type 2. In patients affected with generalized peroxisomal disorders, degradation of both phytanic acid and pristanic acid is impaired owing to absence of functional peroxisomes. In bifunctional protein deficiency, the disturbed oxidation of pristanic acid results in elevated levels of this fatty acid and a secondary elevation of phytanic acid. In addition, several variant peroxisomal disorders with unknown aetiology have been described in which phytanic acid and/or pristanic acid accumulate. This review describes the discovery of phytanic acid and pristanic acid and the initial attempts to elucidate the origins and fates of these fatty acids. The current knowledge on the alpha-oxidation and beta-oxidation of these branched-chain fatty acids is summarized. The disorders in which phytanic acid and/or pristanic acid accumulate are described and some remarks are made on the pathogenic mechanisms of elevated levels of phytanic acid and pristanic acid.
Making sharing pervasive: Ubiquitous computing for shared note taking (1999)

As a variety of low-cost note-taking devices becomes pervasive, shared notes can help work groups better communicate ideas and information. To explore this idea further, we carried out three related case studies of how members of a large research group shared meeting notes. The group found value in combining personal notes and presentation slides with a single, unifying document, such as regular meeting minutes. The minutes provided structure when there were too many sources of notes. We used this insight in our design of NotePals, a note-sharing system with a lightweight process, an interface, and hardware that distinguish it from previous systems. We have developed note-taking applications that run on inexpensive personal digital assistants and other ink-based capture devices, such as the paper-based CrossPad™. Experience with using NotePals has shown that shared notes can add value to meeting, conference, and class records.
Interaction of P-fimbriatedEscherichia coliwith human meconium (1991)

The ability of Escherichia coli with different receptor specificities to interact with meconium was studied. E. coli strains expressing P-fimbriae, specific for Gal alpha 1-4Gal beta-containing receptors, were agglutinated by meconium at high titres. This reaction was inhibited by globotetraosylceramide. The attachment of P-fimbriated E. coli to human colonic epithelial cells of the HT-29 cell line was inhibited by meconium. Some type 1 fimbriated strains were agglutinated by meconium, but the agglutination was rarely blocked by methyl alpha-D-mannoside. The attachment by type 1 fimbriated strains to HT-29 cells was reduced by meconium only in some cases. These results suggest that meconium interacts with the P-fimbriae of E. coli, in a way that may influence bacterial colonization of the neonatal intestine.
Marked in Vivo Donor Regulatory T Cell Expansion via Interleukin-2 and TL1A-Ig Stimulation Ameliorates Graft-versus-Host Disease but Preserves Graft-versus-Leukemia in Recipients after Hematopoietic Stem Cell Transplantation (2017)

Regulatory T cells (Tregs) are critical for self-tolerance. Although adoptive transfer of expanded Tregs limits graft-versus-host disease (GVHD) after hematopoietic stem cell transplantation (HSCT), ex vivo generation of large numbers of functional Tregs remains difficult. Here, we demonstrate that in vivo targeting of the TNF superfamily receptor TNFRSF25 using the TL1A-Ig fusion protein, along with IL-2, resulted in transient but massive Treg expansion in donor mice, which peaked within days and was nontoxic. Tregs increased in multiple compartments, including blood, lymph nodes, spleen, and colon (GVHD target tissue). Tregs did not expand in bone marrow, a critical site for graft-versus-malignancy responses. Adoptive transfer of in vivo-expanded Tregs in the setting of MHC-mismatched or MHC-matched allogeneic HSCT significantly ameliorated GVHD. Critically, transplantation of Treg-expanded donor cells facilitated transplant tolerance without GVHD, with complete sparing of graft-versus-malignancy. This approach may prove valuable as a therapeutic strategy promoting transplantation tolerance.
Lessons Learned from SARS-CoV and MERS-CoV: Preparation for SARS-CoV-2 induced COVID-19 (2020)

Coronaviruses (CoVs) are the largest positive-sense RNA viruses with a wide range of natural hosts. To date, seven types of coronaviruses (
A novel preventive strategy against HIV-1 infection: combinatorial use of inhibitors targeting the nucleocapsid and fusion proteins (2017)

The strategy of simultaneously attacking multiple targets is worthy of exploration in the field of microbicide development to combat HIV-1 sequence diversity and minimize the transmission of resistant variants. A combination of S-acyl-2-mercaptobenzamide thioester-10 (SAMT10), an inhibitor of the HIV-1 nucleocapsid protein (NCp7), and the fusion inhibitor sifuvirtide (SFT) may exert synergistic effects, since SFT can block viral fusion at an early stage of the viral cycle and SAMT10 can disrupt viral particles at a later stage. In this study, we investigated the effect of the combination of SAMT10 and SFT on HIV-1 infection using in vitro cell culture and ex vivo mucosal explant models. A range of doses for each compound was tested at 10-fold serial dilutions based on their 50% effective concentrations (EC<sub>50</sub>). We observed a synergistic effect of SAMT10 and SFT in vitro against both the laboratory-adapted HIV-1 strain HIV-1<sub>IIIB</sub> (subtype B, X4) and three pseudotyped viruses prevalent in Chinese sexually transmitted populations (SVPB16 (subtype B, R5), SVPC12 (subtype C, R5) and SH1.81 (CRF01_AE, R5)). In the ex vivo study, the EC<sub>50</sub> values of the inhibitor combinations were reduced 1.5- to 2-fold in colorectal mucosal explants compared to treatment with SAMT10 or SFT alone by using with HIV-1<sub>IIIB</sub>. These results may provide a novel strategy for microbicide development against HIV-1 sexual transmission.
ChemInform Abstract: Dimethoxy Triazine Glycosides as New Glycosyl Donors for Chemoenzymatic Synthesis of Oligosaccharides (2010)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Physiological Bases of Feeding Behaviour in Salamanders: Do Motor Patterns Vary With Prey Type? (1989)

ABSTRACT Muscle activity patterns (motor patterns) of the jaw musculature of all vertebrates studied to date (primarily fishes and amniotes) vary considerably when they feed on different types of prey. Previous data on buccal pressure patterns suggested that feeding in the aquatic salamander, Ambystoma mexicanum (Shaw), is highly stereotyped. This hypothesis was tested by quantifying the motor pattern used during feeding on two prey types: earthworms and guppies. Twenty-nine variables were measured from the activity pattern of six cranial muscles in the feeding mechanism of Ambystoma mexicanum. These variables included the area under the electromyogram of each muscle, relative muscle onset times, and the amplitudes and durations of muscle bursts. Univariate and multivariate statistical analyses demonstrate that the feeding motor pattern of Ambystoma mexicanum is stereotyped and does not change with prey type, in contrast to motor patterns of other vertebrates studied to date. Individual salamanders use significantly different motor patterns from one another during feeding, but do not alter their motor pattern during feeding on different prey.
Characterization of '2D noise' print defect (2009)

Graininess and mottle described by ISO 13660 standard are two image quality attributes which are widely used to evaluate area uniformity in digital prints. In an engineering aspect, it is convenient to classify and analyze high frequency noise and low frequency noise separately. However, it is continuously reported in previous literature that the ISO methods do not properly correlate with our perception. Since area quality is evaluated by observing all the characteristics with a wide range of spectral frequencies in a printed page, it is almost impossible to differentiate between graininess and mottle separately in our percept. In this paper, we characterize '2D noise' print defect based on psychophysical experiments which appear as two dimensional aperiodic fluctuations in digital prints. For each channel of cyan, magenta, and black, our approach is to use two steps of hybrid filtering to remove invisible image components in the printed area. '2D noise' is computed as the weighted sum of the graininess and mottle, which two weighting factors are determined by subjective evaluation experiment. By conducting psychophysical validation experiments, the strong correlation is obtained between the proposed metric and the perceived scales. The correlation coefficients r2 are 0.90, 0.86, and 0.78 for cyan, magenta and black, respectively.
Modeling of Leaked Digital Video Signal and Information Recovery Rate as a Function of SNR (2015)

Substantial information leakage at PC monitors and TV systems arises in the form of unintentional emissions of high-speed digital video signals, such as DVI/HDMI. The information recovery rate from the emanated video signal varies depending on the SNR of the receiver system, which is placed a certain distance away. In this study, a situation in which the signal from a digital video system is intercepted is modeled using full-wave electromagnetic and circuit simulations. For a quantitative evaluation of the eavesdropping threat of display systems and the effect of its countermeasure, the readability of characters on a hypothetical screen as a function of the BER of the recovery signals is presented. It is clear that a decrease of the SNR of the received signal causes a deterioration of the digital video signal-recovery rate and consequently degrades the legibility of the characters on the intercepted screen. It is expected that these techniques can be useful for measurements and analyses of the effects of countermeasures, such as noise jamming or signal modulation, to prevent interceptions of digital video information.
Simulative Design of a Load-Path Adapted Fibre Reinforced Composite (FRP) Transporter Rear Door (2023)

The demand for weight reduction in the automotive, aerospace, and railway industries is at an all-time high. Fibre-reinforced composites (FRC) have proved their suitability with their excellent combination of strength and weight. The only limiting factor in adapting FRC for mass-production in industries is the high costs of composite materials like carbon fibre reinforced plastics. A design workflow, suitable for FRC’s and their available manufacturing technologies has been proposed by adopting a progressive approach. A multi-material component design has been optimized using Altair Hyperworks and OptiStruct to reduce weight and maintain stiffness and strength as compared to its conventional metallic version. The layup of the substrate laminate has been optimized using special optimization tools in OptiStruct in three stages. The determination of load-paths is followed by the optimization of the base laminate under given load cases. Subsequently, the geometry of injection-moulded stiffeners was determined by employing topology optimization considering the composite layup, obtained in previous steps.
ChemInform Abstract: Regio‐ and Stereoselective Hydrostannylation of 3‐Hydroxy‐4‐phenoxy‐1‐butyne: Effective Approach to Intermediates in the Total Synthesis of ω‐Aryloxy‐prostaglandins. (1986)

Abstract Durch Hydrostannylierung der Butinol‐Derivate (I) mittels TributyIzinnhydrid und anschließende Umsetzung mit Iod werden die Iodcarbinole (III), (VI) und (VIII) zugänglich, die zur Synthese von Prostaglandinen von Interesse sind.
Detection free tracking: Exploiting motion and topology for segmenting and tracking under entanglement (2011)

We propose a detection-free system for segmenting multiple interacting and deforming people in a video. People detectors often fail under close agent interaction, limiting the performance of detection based tracking methods. Motion information often fails to separate similarly moving agents or to group distinctly moving articulated body parts. We formulate video segmentation as graph partitioning in the trajectory domain. We classify trajectories as foreground or background based on trajectory saliencies, and use foreground trajectories as graph nodes. We incorporate object connectedness constraints into our trajectory weight matrix based on topology of foreground: we set repulsive weights between trajectories that belong to different connected components in any frame of their time intersection. Attractive weights are set between similarly moving trajectories. Information from foreground topology complements motion information and our spatiotemporal segments can be interpreted as connected moving entities rather than just trajectory groups of similar motion. All our cues are computed on trajectories and naturally encode large temporal context, which is crucial for resolving local in time ambiguities. We present results of our approach on challenging datasets outperforming by far the state of the art.
Dendritic polyisophthalate endcapped with naphthyl groups for holographic recording (2004)

Abstract A novel dendritic polyisophthalate with 12 naphthyl groups at the chain ends was synthesized from 5‐hydroxyisophthalic acid as an AB 2 monomer, 1,3,5‐benzenetricarbonyl trichloride as an ‘initiator core’ molecule, and β ‐naphthol as an endcapping reagent, via a stepwise growth process. An average molecular weight of 2860 g mol −1 , and a refractive index of 1.618 at 650 nm were obtained by gel permeation chromatography and ellipsometry, respectively. A photopolymerizable recording dry film incorporating this dendrimer as a polymeric binder was used for holographic recording. Diffraction gratings with diffraction efficiency exceeding 80%, together with a modulation index of 10 −2 were obtained. Copyright © 2004 John Wiley &amp; Sons, Ltd.