gebhart/patrepeval huggingface dataset:
Zeta Potential of Hollow Fiber Dialysis Membranes and Its Effects on Hydrogen Phosphate Ion Permeability (1993)

To clarify ion transport, dialysis membranes are evaluated in terms of zeta potential calculated by the Helmholtz-Smoluchowski equation from data on streaming potential delta E and pressure drop delta P, depending upon the operating conditions at which the values are measured. The objective of the current study is to design an improved method for measurement of delta E and delta P of hollow fiber dialysis membranes and to clarify the diffusive permeability of hydrogen phosphate ion. A polytetrafluoroethylene cylindrical cell with an inside diameter of 14 mm and a height of 10 mm was packed with 2,000-3,000 pieces of hollow fibers, and glass filters were set on either side of the cell. Deaerated water purified by ion exchange and reverse osmosis with an electric conductivity of approximately 150 microS/m was caused to flow in the hollows at 293 K to determine delta E and delta P. A good linear relationship between delta E and delta P and the reproducibility of the data was obtained and is shown in Figures 5 and 6, demonstrating the utility of the improved method to measure delta E and delta P, and the validity of the Helmholtz-Smoluchowski equation to calculate zeta potential from data on delta E and delta P. Hydrogen phosphate ion permeability increased with zeta potential for the membranes at about the same rate as pure water permeability. This indicates that hydrogen phosphate ion permeability depends upon the charge and internal structure of dialysis membranes.
Apply a TADF emitter with twist configuration for high-performance green OLEDs (2022)

Abstract Due to the strong concentration quenching effect, the development of non-doped devices with excellent performance is limited. Herein, a novel thermally activated delayed fluorescence (TADF) emitter which contain Spiro[anthracene-9(10H),9’-[9H]fluoren]-10-one (9-FAO) and 9,9-dimethyl-9,10-dihydroacridine (DMAC) was designed and synthesized. The compound shows TADF characteristics which can be observed by transient PL decay tests. By introducing DMAC into the para-position of the 9-FAO which has a highly twisted structure, the distance between the molecules increases to inhibit concentration quenching. The non-doped OLED device by using 2-(9, 9-dimethylacridin-10(9H)-yl)-10H-spiro[anthracene-9,9’- fluoren]-10-one (DMTO-DMAC) as emitter achieved a superior current efficiency of 35.6 cd A −1 and maximum external quantum efficiency of 11.3% with an emission peak at 516 nm. This work demonstrates the feasibility of increasing intermolecular distance to obtain highly efficient non-doped devices.
[Active immunization of male pigs against gonadoliberin: effect on the secretion of gonadotropic hormones and on 5 alpha-androst-16-ene-one levels in adipose tissue]. (1986)

27 boars aged 100 days were allocated to 3 experimental groups. The control group was untreated. The 2 other groups were given injections of LHRH, bound to BSA, with either Freund complete adjuvant or alumina gel. 4 immunisations were achieved at weekly intervals and a fifth injection was performed after 4 weeks. In animals treated with alumina gel, no specific antibodies were obtained. In the other hand, all 9 boars treated with FCA exhibited significant titers of specific anti-LHRH antibodies. In these animals, the neutralisation of blood LHRH induced a significant decline in both LH and FSH concentrations. Consequently, fat androstenone levels dropped dramatically, down to low levels, similar to those observed in surgically castrated males.
Information retrieval and laboratory data management (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTInformation retrieval and laboratory data managementR. E. Dessy and M. K. StarlingCite this: Anal. Chem. 1979, 51, 9, 924–948Publication Date (Print):August 1, 1979Publication History Published online21 September 2008Published inissue 1 August 1979https://pubs.acs.org/doi/10.1021/ac50045a001https://doi.org/10.1021/ac50045a001research-articleACS PublicationsRequest reuse permissionsArticle Views57Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Collaborative ordinal regression (2006)

Ordinal regression has become an effective way of learning user preferences, but most research focuses on single regression problems. In this paper we introduce collaborative ordinal regression, where multiple ordinal regression tasks are handled simultaneously. Rather than modeling each task individually, we explore the dependency between ranking functions through a hierarchical Bayesian model and assign a common Gaussian Process (GP) prior to all individual functions. Empirical studies show that our collaborative model outperforms the individual counterpart in preference learning applications.
Food science: basic research for technological progress. Proceedings of the symposium in honour of Professor W. Pilnik, Wageningen, 1988. (1989)

Studies on the low temperature infrared heat processing of soybeans and maize.D
Design and characterization of novel W-band wide-band couplers and six-port circuit (2015)

This paper presents a comprehensive analyze of a novel six-port circuit operating over 10 GHz band from 80 to 90 GHz. The circuit is fabricated using hybrid integrated technology on a ceramic substrate using an in-house process. Two-port S-parameter measurements are performed on a number of circuits integrated on the same die, chosen to collect enough data for its full-port characterization. A circuit computer model is implemented using previous measurements and used to characterize the circuit as a quadrature demodulator. Error vector modulation analysis confirms that the circuit is able to demodulate with very good results various PSK and QAM signals over the 10 GHz band.
A Paradigm Shift for the Amino Acid Editing Mechanism of Human Cytoplasmic Leucyl-tRNA Synthetase (2009)

Leucyl-tRNA synthetase (LeuRS) has been identified as a target for a novel class of boron-containing small molecules that bind to its editing active site. When the 3' end of tRNA(Leu) binds to the editing active site, the boron cross-links to the cis-diols of its terminal ribose. The cross-linked RNA-protein complex blocks the overall aminoacylation activity of the enzyme. Similar to those of other LeuRSs, the human cytoplasmic enzyme (hscLeuRS) editing active site resides in a discrete domain called the connective polypeptide 1 domain (CP1), where mischarged tRNA binds for hydrolysis of the noncognate amino acid. The editing site of hscLeuRS includes a highly conserved threonine discriminator and universally conserved aspartic acid that were mutationally characterized. Substitution of the threonine residue to alanine uncoupled specificity as in other LeuRSs. However, the introduction of bulky residues into the amino acid binding pocket failed to block deacylation of tRNA, indicating that the architecture of the amino acid binding pocket is different compared to that of other characterized LeuRSs. In addition, mutation of the universally conserved aspartic acid abolished tRNA(Leu) deacylation. Surprisingly though, this editing-defective hscLeuRS maintained fidelity. It is possible that an alternate editing mechanism may have been activated upon failure of the post-transfer editing active site.
Project Group HAGS Product plan (1995)

This report is a productplan for AB HAGS Mekaniska in Aneby Sweden. HAGS is the market leader for playground equipment and park furniture. Our product plan introduces a new consept for a product li ...
SIMULTANEOUS DIOPHANTINE APPROXIMATION ON POLYNOMIAL CURVES (2009)

The Hausdorff dimension and measure of the set of simultaneously ψ-approximable points lying on integer polynomial curves is obtained for sufficiently small error functions.
Risk factors for heart, cerebrovascular, and kidney diseases: evaluation of potential side effects of medications to control hypertension, hyperglycemia, and hypercholesterolemia (2023)

No experimental interventions were performed. As the dataset was comprised of the results of health checkups of workers in Japan, individuals aged 76 and above were not included. Since the dataset only contained information obtained in Japan and the Japanese are ethnically homogeneous, potential ethnic effects on the diseases were not evaluated.
Strategic and competitive success: towards a model of the comprehensively competent organization (1996)

Draws together a number of themes from mainstream strategy literature and synthesizes them into a new model of the comprehensively competent organization. Argues that it is a key role of the strategic leader to ensure that his/her organization possesses a wide range of generic competences (to an appropriate degree in each case) in order that the organization can develop and sustain more specific competences in learning, change management and product/service competitive competency. These “layers of competence” are illustrated in the form of an integrated web. While it is content competences which ultimately produce successful competitive outcomes, other competences in learning and change management are needed to support this. The competence implications of modern environments are discussed and, towards the end of the article, the generic competence argument is applied to the literature on business failure.
A Blockchain-based Platform Architecture for Multimedia Data Management (2020)

Massive amounts of multimedia data (i.e., text, audio, video, graphics and animation) are being generated everyday. Conventionally, multimedia data are managed by the platforms maintained by multimedia service providers, which are generally designed using centralised architecture. However, such centralised architecture may lead to a single point of failure and disputes over royalties or other rights. It is hard to ensure the data integrity and track fulfilment of obligations listed on the copyright agreement. To tackle these issues, in this paper, we present a blockchain-based platform architecture for multimedia data management. We adopt self-sovereign identity for identity management and design a multi-level capability-based mechanism for access control. We implement a proof-of-concept prototype using the proposed approach and evaluate it using a use case. The results show that the proposed approach is feasible and has scalable performance.
ACTR-43. GENOMIC ANALYSIS OF RESPONDERS OF PHASE II TRIAL OF TEMOZOLOMIDE AND TRC-102 (BASE EXCISION REPAIR INHIBITOR) IN BEVACIZUMAB-NAÏVE GLIOBLASTOMA AT FIRST RECURRENCE (2019)

Abstract BACKGROUND Temozolomide forms O6-methylguanine (O6mG), 7-methylguanine (N7mG), and 3- methyladenine (N3mA) DNA adducts. The O6mG DNA adduct is repaired by MGMT. N7mG and N3mA DNA adducts are removed by the base excision repair (BER) pathway, initiated by N- methylpurine DNA glycosolase (MPG). TRC-102 is a BER inhibitor that binds to the apurinic site created through the action of MPG. METHODS A phase II study of adult glioblastoma in first recurrence was performed in the Adult Brain Tumor Consortium with temozolomide, 150 mg/ m2 and TRC-102, 150 mg (1–5/ 28 days). Primary objective included radiographic response rate. Secondary objectives included safety and PFS-6. Exploratory objectives included tumor expression of N-methylpurine DNA glycosylase (MPG). The study tested hypothesis that combination therapy will achieve 30% RR. To understand the context of vulnerability to TRC102 we performed RNA sequencing on treatment naïve tissue from 7 patients. RESULTS Nineteen patients were enrolled in first stage. Median age was 60 years (range: 48–76), 53% females, median KPS was 80 (range: 70–90). Median cycles of treatment was 2 (range: 1–12). No responses were observed. Median OS was 11.0 months (95% CI: 8–18 months), median PFS was 2.0 months (95% CI: 1.8–3.6 months). PFS-6 rate was 10.5 % (2/19). The combination was safe. MPG staining was negative in six, 1+ in five and 2+ in three patients. PFS of 11 + months in two patients (exceptional responders) was associated with MPG expression. Preliminary analysis on RNA sequencing revealed significant enrichment for DNA Damage Response pathways (MsigDB), chromosomal instability gene signature (CIN70 and CIN25), and proliferative gene signature (PCNA25) in these 2 patients. CONCLUSIONS TRC 102 with temozolomide has acceptable safety but did not meet the primary endpoint of response. Gene signature of MsigDB, CIN70, CIN25 and PCNA25 was seen in exceptional responders and biomarker driven study is planned.
The Semicrystalline Morphology of Poly(ether−ether−ketone) Blends with Poly(ether−imide) (1998)

The microstructure of cold-crystallized poly(ether−ether−ketone)/poly(ether−imide) (PEEK/PEI) blends has been investigated by a combination of wide- and small- angle X-ray scattering (SAXS), dielectric spectroscopy, and transmission electron microscopy. Both SAXS and dielectric spectroscopy indicate that most PEI is excluded from interlamellar regions and segregates essentially into interfibrillar regions upon crystallization. Interlamellar inclusion was found to be limited to low PEI levels. Transmission electron microscopy (TEM) observations on stained thin sections from bulk samples confirm these conclusions. The restricted character of the interlamellar inclusion of PEI is probably due to a more ordered structure of noncrystalline regions near PEEK crystal surfaces. In addition, our results on PEEK/PEI blends corroborate the model of cold-crystallized pure PEEK which consists of thin lamellar crystals separated by thicker noncrystalline interlayers that are grouped into stacks of limited coherence and uniformly fill the entire sample volume without any separate amorphous pockets or gaps.
Supplementary Table 1, Figures 1 - 5 from Targeted Delivery of <i>microRNA-29b</i> by Transferrin-Conjugated Anionic Lipopolyplex Nanoparticles: A Novel Therapeutic Strategy in Acute Myeloid Leukemia (2023)

&lt;p&gt;PDF file - 325K, Supplemental Table 1: Particle Size Distribution and Zeta Potential; Supplemental Figure 1: Transferrin receptor (CD71) expression on AML patient blasts; Supplemental Figure 2: miR entrapment efficiency; Supplemental Figure 3: Relative expression of miR-29b in AML cell lines, patient blasts and bone marrow samples from healthy donors; Supplemental Figure 4: Expression of pri-miR-29b-1 and pri-miR-29b-2 in AML cell lines and patient blasts following Tf-NP-miR-29b treatment; Supplemental Figure 5: Safety profile of Tf-NPs treatment in immune competent mice.&lt;/p&gt;
Evidence of Morphological Change in Sulfur Cathodes upon Irradiation by Synchrotron X-rays (2022)

While the development of lithium–sulfur battery cathodes has benefited substantially from the use of in situ and ex situ X-ray absorption studies, the degree of undesired influence from synchrotron radiation has not been studied. In this work, we present evidence of severe beam damage on sulfur cathodes under irradiation by synchrotron X-rays. Specifically, X-ray fluorescence mapping with relatively low dosage was conducted to observe the morphological changes after conducting X-ray absorption spectroscopy (XAS). Under open-circuit conditions, the morphology of the sulfur spontaneously changes and tends to migrate out of the region of XAS sampling. Our work indicates that effort should be placed in first obtaining a no-change/stable open-circuit baseline when attempting to conduct in operando studies of lithium–sulfur batteries using synchrotron radiation with an energy of <7.7 keV and a flux of >6 × 1012 photons s–1.
Statistical technique to identify clusters from multi-dimensional measurement data (2007)

This paper presents a statistical technique to be applied to multi-dimensional (MD) channel estimation data to objectively establish the presence of clusters of the multi-path components (MPCs). The key insight is that by dividing the MD measurement data space into MD analysis regions (MDARs), we can compare the distributions both of the number of the MPCs and the total power for the MPCs within a MDAR, with those distributions when the MPCs are random and uncorrelated in the MD data space. Hence we may confirm or reject the presence of significant clustering. This statistical technique has been applied to high-resolution indoor multi-input multi-output (MIMO) measurement data at 2.55 GHz to evaluate its applicability, validity and reliability. By analyzing the measurement data using the technique, we found that the statistical technique has good performance in identifying the existence of clusters in two respects, i.e. the probability density functions (PDFs) of both the number and the total power of the MPCs in an MDAR. (7 pages)
Are Children Like Werewolves? Full Moon and Its Association with Sleep and Activity Behaviors in an International Sample of Children (2016)

In order to verify if the full moon is associated with sleep and activity behaviors, we used a 12-country study providing 33,710 24-h accelerometer recordings of sleep and activity. The present observational, cross-sectional study included 5812 children ages 9-11 years from study sites that represented all inhabited continents and wide ranges of human development (Australia, Brazil, Canada, China, Colombia, Finland, India, Kenya, Portugal, South Africa, United Kingdom, and United States). Three moon phases were used in this analysis: full moon (±4 days; reference), half moon (±5-9 days), and new moon (±10-14 days) from nearest full moon. Nocturnal sleep duration, moderate-to-vigorous physical activity (MVPA), light-intensity physical activity (LPA), and total sedentary time (SED) were monitored over seven consecutive days using a waist-worn accelerometer worn 24 h a day. Only sleep duration was found to significantly differ between moon phases (~5 min/night shorter during full moon compared to new moon). Differences in MVPA, LPA, and SED between moon phases were negligible and non-significant (<2 min/day difference). There was no difference in the associations between study sites. In conclusion, sleep duration was 1% shorter at full moon compared to new moon, while activity behaviors were not significantly associated with the lunar cycle in this global sample of children. Whether this seemingly minimal difference is clinically meaningful is questionable.
Cytokine Biomarker Candidates in Breast Milk Associated With the Development of Atopic Dermatitis in 6-Month-Old Infants (2013)

S Ochiai, N Shimojo, Y Morita. Int Arch Allergy Immunol . 2013;160(4):401–408

The authors identified various breast milk cytokines and chemokines that appeared to be related to the presence of infantile atopic dermatitis (AD).

Japanese infants with and without a history of AD at 6 months of age were recruited from January 2007 to May 2008. Each cohort had 49 infants; 35% of the study population and 47% of the control population were female. About 41% were exclusively breast-fed in each group; the remainder was breast- and formula-fed.

The authors compared the chemokine/cytokine profiles in …
In vitrosusceptibility patterns ofAspergillusandFusariumspecies isolated from equine ulcerative keratomycosis cases in the midwestern and southern United States with inclusion of the new antifungal agent voriconazole (2009)

Based on in vitro evidence, voriconazole appears to be the most effective antifungal for initial treatment of equine keratomycosis in the midwestern and southern United States. Results are comparable with previous studies in that isolated fungi from equine keratomycosis cases showed consistently poor susceptibility to fluconazole. Organisms isolated in different geographic locations of the midwestern and southern United States appeared to have similar patterns of antifungal susceptibility.
The Incidence Prognosis and Risk Factors of Cognitive Impairment in Maintenance Haemodialysis Patients (2018)

CI is one of the most common complications in MHD patients. The mortality is high in patients who had CI. Education status, post-dialysis diastolic pressure and spKt/V are independent risk factors for CI in MHD patients.
The content and composition of organic compounds in the snow-ice cover of the White Sea (2009)

This paper reports data on the concentrations of organic compounds (organic carbon, Corg; lipids; aliphatic hydrocarbons, AHCs; and polycyclic 0aromatic hydrocarbons, PAHs) in snow, ice, and subice waters from the mouth of the Severnaya Dvina River (2005–2007) and Kandalaksha Gulf (Chupa Bay, 2004) at the end of winter. It was established that organic compounds are accumulated in the snow and upper ice layer near the town of Archangelsk. The distribution of molecular markers indicates that pollution was mainly caused by local fallouts. In Chupa Bay, organic compounds are concentrated in the lower ice layers, which is typical of the Arctic snow-ice cover. The high contents of organic compounds in the snow-ice cover of the White Sea are caused by the pollution of its air and water during the winter season.
Improvement of the Productivity in the THM Growth of CdTe Single Crystal as Nuclear Radiation Detector (2010)

The effect of the THM growth rate on the CdTe crystalline quality and the detector performance was intensively investigated. The maximum growth rate for the single crystal growth was found to be approximately 15 mm/day which was 3 times greater than the conventional one. By optimizing other growth conditions, 90% of every ingot volume has become a single crystal. Te inclusions in the CdTe single crystal grown at various growth rates were also investigated by IR transmission microscopy. There was no correlation between the behavior of Te inclusions and the growth rate. The detector performance was also independent of the growth rate. Taking advantage of the large volume CdTe single crystals, about 700 000 Schottky detectors with 4 mm × 7.5 mm × 1 mm were fabricated for the research and development of the new positron emission tomography (PET) system using CdTe detectors. The average FWHM for the 662 keV line from <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">137</sup> Cs and its standard deviation were 2.24% and 0.48%, respectively. This uniformity was essential for the development of the new PET system.