gebhart/patrepeval huggingface dataset:
Toward a deeper use of feedback control in the design of critical computing system components (2010)

Feedback controllers are typically applied to computing systems by acting on some quantities (“tunable parameters” in the computer science lexicon, think e.g. of a packet drop rate) in order to attain some goal (e.g., a required bandwidth allocation). In other words, control loops are closed around the computing system, that exposes tunable parameters as control actuators, and allows to measure some performance metrics. In the authors' opinion, the “classical” use of control methods sketched above heavily limits the achievable results. Indeed, many critical parts of computing systems should not be “controlled”, but rather “re-designed in the form of controllers” - quite a novel approach and an interesting research area. This manuscript formalises the statement above and illustrates some results, including a couple of application examples, to demonstrate the advantages of the proposed design approach.
Triazolo[4,5-d]pyrimidines. X. Halogen-Metal Exchange Reaction of 7-Halo-3-phenyl-3H-1,2,3-triazolo[4,5-d]pyrimidines with Butyllithium. (1991)

The amino group at the 7-position on the 3H-1, 2, 3-triazolo[4, 5-d]pyrimidine ring was converted into halogen atoms by treatment with isopentyl nitrite in halomethanes, in satisfactory yields. The halogen-metal exchange reaction between 7-iodo-3-phenyl-3H-1, 2, 3-triazolo[4, 5-d]pyrimidine (2) and butyllithium in the presence of N, N, N', N'-tetramethylethylenediamine proceeded, giving the 7-lithio compound (9). The lithio compound (9) reacted smoothly with electrophiles to give the corresponding 7-substituted compounds (15-18). On the other hand, the reaction of 7-chloro-3-phenyl-3H-1, 2, 3-triazolo[4, 5-d]pyrimidine (1) with butyllithium gave the ring fission product, 5-amino-1-phenyl-1H-1, 2, 3-triazole-4-carbonitrile (14).
ChemInform Abstract: METAL COMPLEXES OF HEMILABILE LIGANDS. REACTIVITY AND STRUCTURE OF DICHLOROBIS(O‐(DIPHENYLPHOSPHINO)ANISOLE)RUTHENIUM(II) (1980)

Abstract Der durch Behandlung von"EngelhardtÜRu‐trichlorid mit 0‐Diphenylphosphinoanisol gebildete Komplex (I) wird als Methylenchlorid‐Monosolvat mittels einer Einkristall‐Röntgenanalyse charakterisiert.
Study of HIV‐2 primer–template initiation complex using antisense oligonucleotides (2000)

HIV-2 reverse transcription is initiated by the retroviral DNA polymerase (reverse transcriptase) from a cellular tRNALys3 partially annealed to the primer binding site in the 5'-region of viral RNA. The HIV-2 genome has two A-rich regions upstream of the primer binding site. In contrast to HIV-1 RNA, no direct evidence of interactions with the U-rich anticodon loop of tRNALys3 has been described to date. Here we address the question of the potential role of the interactions between these highly structured regions in the initiation of viral DNA synthesis. To evaluate this we used an antisense approach, first validated in our in vitro HIV-1 reverse transcription system. Annealing of the antisense oligonucleotides to the pre-primer binding site (the upstream region contiguous to the HIV-2 primer binding site) was determined in the presence of native tRNALys3 or synthetic primers. Using natural and chemically modified antisense oligonucleotides we found that interactions between the anticodon of tRNALys3 and an A-rich loop of viral RNA led to an important destabilization of the pre-primer binding site; this region became accessible to anti-pre-primer binding site oligonucleotides in a cooperative manner. These studies allowed to identify an A-rich region in HIV-2ROD RNA capable of interacting with tRNALys3. Better knowledge of these interactions is very important for understanding the primer/template positioning in the early steps of HIV-2 reverse transcription.
p-Type Photoelectric Behavior in CdS Dominated by a High-Resistivity Region near the Anode (1967)

It is observed, using the Franz-Keldysh effect, that certain very pure CdS crystals show a high-field layer close to, but well separated from, a hole-injecting anode (Au). Inversion of an infrared quenching spectrum into a similar infrared excitation spectrum is observed at an applied voltage where this high-field layer becomes "visible." The data are tentatively interpreted in terms of a model with a current-controlling $p$-type region adjacent to the anode and produced by hole injection, followed by a $p\ensuremath{-}n$ junction identified with the observed high-field region, followed by the normal $n$-type region occupying most of the bulk.
Effect of the Medicinal Mushroom, Grifola gargal (Agaricomycetes), on Bone Turnover Markers and Serum Lipids in Middle-Aged and Elderly Japanese Women (2016)

A clinical study was performed to examine the effect of the edible mushroom, Grifola gargal, on bone turnover markers and serum lipids in middle-aged and elderly Japanese women. Postmenopausal women aged 51-73 years (mean age, 61 years) received daily oral administration of 5 g G. gargal fruiting bodies (hot air-dried and powdered; G. gargal powder [GGP]). Serum levels of bone alkaline phosphatase (BAP) and lipids and urinary deoxypyridinoline (DPD) levels were measured before and 2 weeks after the start of GGP treatment. As a result, urinary DPD bone resorption marker levels in women treated with GGP decreased significantly. Serum levels of the BAP bone formation marker also tended to increase, but the difference was not significant. By contrast, the atherogenic index decreased and the high-density lipoprotein (HDL) ratio increased significantly. However, there were no statistically significant differences in serum lipids of total cholesterol, HDL cholesterol, and low-density lipoprotein cholesterol. In addition, this study demonstrated for the first time that G. gargal is safe for human consumption.
Surface-Enhanced Raman Scattering Tags for Rapid and Homogeneous Detection of Circulating Tumor Cells in the Presence of Human Whole Blood (2008)

A novel, homogeneous SERS-based cell detection assay was developed for rapid and direct enumeration of circulating tumor cells in the presence of whole blood. Magnetic beads and SERS tags were respectively conjugated to EpCAM and her2 antibodies for the capture and detection of approximately 50 tumor cells/mL in the presence of whole blood in less than 1 h.
Selective Alcohol Dehydrogenation and Hydrogenolysis with Semiconductor-Metal Photocatalysts: Toward Solar-to-Chemical Energy Conversion of Biomass-Relevant Substrates (2012)

Photocatalytic conversion of biomass is a potentially transformative concept in renewable energy. Dehydrogenation and hydrogenolysis of biomass-derived alcohols can produce renewable fuels such as H2 and hydrocarbons, respectively. We have successfully used semiconductor-metal heterostructures for sunlight-driven dehydrogenation and hydrogenolysis of benzyl alcohol. The heterostructure composition dictates activity, product distribution, and turnovers. A few metal (M = Pt, Pd) islands on the semiconductor (SC) surface significantly enhance activity and selectivity and also greatly stabilize the SC against photoinduced etching and degradation. Under selected conditions, CdS-Pt favors dehydrogenation (H2) over hydrogenolysis (toluene) 8:1, whereas CdS0.4Se0.6-Pd favors hydrogenolysis over dehydrogenation 3:1. Photochemically generated, surface-adsorbed hydrogen is useful in tandem catalysis, for example, via transfer hydrogenation. We expect this work will lead to new paradigms for sunlight-driven conversions of biomass-relevant substrates.
Microdosing as a Potential Tool to Enhance Clinical Development of Novel Antibiotics: A Tissue and Plasma PK Feasibility Study with Ciprofloxacin (2022)

ClinicalTrials.gov NCT03177720 (registered 6 June, 2017).
THE DIAGNOSTIC VALUE OF SERUM LDH ISOENZYMES AND HEAT‐STABLE AND UREA‐STABLE LDH MEASUREMENTS (1971)

Abstract. Serum heat‐stable and urea‐stable LDH measurements have been found to detect acute myocardial infarction more sensitively than the separation of LDH 1 or LDH 2 isoenzymes with agar gel electrophoresis. On the other hand, serum heat‐stable and urea‐stable LDH tests gave better information of myocardial damage if the serum LDH pattern was confused by simultaneous augmentations of liver‐originated LDH isoenzymes. The simple heat‐stable and urea‐stable LDH measurements thus seem to give more accurate confirmation of myocardial damage than the more complicated electrophoretic separation of LDH isoenzymes.
Production of a common epitope specific anti-ankyrin monoclonal antibody (2022)

Background: Ankyrin (Ank) is a protein family with crucial roles in retaining normal cellular physiology. In addition, ankyrin offers the potential as a non-antibody binder against various biomolecules. The designed ankyrin repeat protein (DARPin) selected from phage display libraries is useful for molecular detection and therapy. Monoclonal antibodies (mAbs) specific to the common epitope of DARPin are required to detect protein-protein interaction. Objectives: This study aimed to establish mAbs against common antigenic determinant of ankyrins for further application in immunological techniques. Materials and methods: Ank1D4 monomer and dimer were generated in the Escherichia coli expression system for immunogen preparation and validation of established mAbs. The binding activity of anti-Ank mAb obtained from different hybridoma clones was characterized using Ank1D4 by indirect ELISA. Candidate anti-Ank mAbs were validated for their cross-reactivity against irrelevant ankyrin (Ank2D3). The binding kinetic of mAbs from three candidate hybridoma clones (Ank-54, Ank-59, and Ank-94) was evaluated using bio-layer interferometry (BLI). The highest affinity clone (Ank-94 mAb ) was further validated for its specificity against Ank1D4 and dimeric Ank1D4 using indirect ELISA. The interaction of three anti-Ank mAbs and ankyrins was compared by western immunoblotting analysis. The specificity of Ank-94 mAb was determined using a closely related scaffold, i.e., alpha-helicoidal HEAT-like repeat protein scaffold (αRep) by indirect ELISA. Ankyrins were detected by sandwich ELISA using Ank-94 mAb. Results: The culture supernatant from hybridoma clones were characterized for their anti-ankyrin binding properties. Using indirect ELISA, three clones exhibited positive reactivity against the immunized ankyrin antigen (Ank1D4). The interactive epitope was found to rely on common antigenic determinants found in Ank1D4, dimeric Ank1D4, and an irrelevant ankyrin, Ank2D3. The immunoblotting results suggest that all mAbs interact with the sequential epitope of ankyrins. The cross-reactivity of Ank-94 mAb was not observed with αRep. Ank-94 mAb was selected for further purification and evaluation of binding properties due to its highest degree of binding affinity against Ank1D4. Conclusion: The establishment of a novel Ank-94 mAb could be a valuable research tool in tracing the target of DARPins or developing immunoassays. Ank-94 mAb is superior over formerly produced Ank mAbs since it recognizes a common epitope on DARPins and relies on sequential epitope. Ank-94 mAb has no cross-reactivity with another scaffold, αRep.
Ordered Liquid Aluminum at the Interface with Sapphire (2005)

Understanding the nature of solid-liquid interfaces is important for many processes of technological interest, such as solidification, liquid-phase epitaxial growth, wetting, liquid-phase joining, crystal growth, and lubrication. Recent studies have reported on indirect evidence of density fluctuations at solid-liquid interfaces on the basis of x-ray scattering methods that have been complemented by atomistic simulations. We provide evidence for ordering of liquid atoms adjacent to an interface with a crystal, based on real-time high-temperature observations of alumina-aluminum solid-liquid interfaces at the atomic-length scale. In addition, crystal growth of alumina into liquid aluminum, facilitated by interfacial transport of oxygen from the microscope column, was observed in situ with the use of high-resolution transmission electron microscopy.
Decision letter: A role for CIM6P/IGF2 receptor in memory consolidation and enhancement (2020)

Cation-independent-mannose-6-phosphate-receptor, or insulin-like-growth-factor-2-receptor (CIM6P/IGF2R) expressed in the hippocampus controls the protein metabolism regulated by learning and required for memory consolidation, and is also a key mechanism for memory enhancement.
Synthesis of New Trans Double-Bond Sphingolipid Analogues:  Δ4,6 and Δ6 Ceramides (2002)

Unsaturation was introduced at Delta(4,6) and Delta(6) of the sphingoid chain of naturally occurring ceramide 1 via a beta-keto sulfoxide (12) and sulfone (18) derived from N-Boc-L-serine methyl ester acetonide (9), affording two novel ceramide analogues, (2S,3R)-2-octanoylamidooctadeca-(4E,6E)-diene-1,3-diol (2) and (2S,3R)-2-octanoylamidooctadec-(6E)-ene-1,3-diol (3). After C-alkylation of 12 with (E)-1-bromo-2-tetradecene (8), a trans double bond was installed by elimination of PhS(O)H, providing conjugated dienone oxazolidine 13. Reaction of 18 with 8, followed by desulfonation (Al(Hg)), afforded keto-oxazolidine 20, which bears a (E)-Delta(6) double bond. The syntheses of analogues 2 and 3 from ketones 13 and 20, respectively, were completed by the following sequence of reactions: diastereoselective reduction (NaBH(4)/CeCl(3) or DIBAL-H), hydrolysis of the oxazolidine ring, liberation of the amino group, and installation of the N-amide group.
Neurosarcoidosis (1987)

CSF lymphocyte subpopulations of eight patients with neurosarcoidosis were examined. CSF or CT was abnormal in all. The CSF T4/T8 (helper/suppressor) ratio was elevated at 6.8 and 7.6 in two patients; in one, there were only CSF T4 cells. The ratio was normal in five patients.
Синтез и фармакологическая активность ароилметилзамещенных трициклических бензимидазольных систем, содержащих гидроксигруппы в ароильном радикале (2007)

The synthesis and pharmacological properties of a series of aroylmethyl derivatives of tricyclic benzimidazole systems containing hydroxy groups in aroyl radical are described. It is established that most of the synthesized compounds exhibit a high antioxidant activity, possess pronounced hemorheological properties, and influence the blood glucose level.
ChemInform Abstract: Suzuki—Miyaura Cross‐Coupling Reactions in a Solkane365/227/Ethanol Blend at Ambient Temperature. (2012)

Abstract An environmentally benign solvent system is developed which also allows the synthesis of polyaryls such as (VIII) or (XI).
New Method to Adsorb Dye Molecules for Dye Sensitized Solar Cell (2006)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
The evolution of comprehensive cancer care in Western Kenya (2013)

In the next 20 years, it is expected that 70% of incident cancers will be diagnosed in the developing world. There exist very few models of cancer care delivery in resource constrained settings. We present a model of cancer care delivery that developed as a result of a multi-institutional collaboration between high-income country academic medical centers and a Kenyan medical school and governmental referral hospital. Based on the infrastructure provided by a successful HIV care program, AMPATH-Oncology presently offers a range of clinical services across the continuum of care, including cervical cancer and breast cancer screening, palliative care, and oncology clinics in pediatric, adult, and gynecology oncology. This program grew from 346 patient visits amongst a few dozen patients in 2004 to over 30,000 visits by 2012 between screening programs and treatment programs. This paper describes the development of the program over a 7-year period.
마음챙김기반 읽기중재가 학습장애 학생의 주의집중행동 및 읽기유창성에 미치는 효과 (2015)

학습장애 학생은 주의집중력과 기억시스템 등의 다양한 문제들로 인해 읽기학습에 심각한 장애를 겪고 있다. 그러므로 학습장애 학생의 주의를 집중시키고 능동적인 자기조절과 통제 능력을 향상시킬 수 있는 읽기중재전략이 필요하다. 이러한 이유들에 근거하여 본 연구는 마음 챙김기반 읽기중재가 학습장애 학생의 주의집중행동과 읽기유창성에 어떠한 긍정적인 효과를 미치는지를 알아보기 위한 목적으로 실시하였다. 이와 같은 목적을 수행하기 위해서 본 연구는 단일대상연구의 대상자간 중다기초선설계를 바탕으로 하여, 초등학교 5학년에 재학 중인 3명의 학습장애 학생을 대상으로 마음챙김기반 읽기중재를 실시하였다. 중재는 준비와 도입, 마음챙김 명상, 읽기유창성검사, 읽기중재, 읽기중재 후 마음챙김 명상, 평가와 마무리의 6단계로 나누었으며, 매회기 총 50분간 20회기가 실시되었다. 이에 대해 주의집중행동은 직접관찰기록, 일화기록과 간단한 부모면담을 통해 자료를 수집하였고, 읽기유창성은 BASA 읽기유창성검사를 실시하여 자료를 수집하였다. 이러한 자료의 수집을 통해 빈도와 백분율 등의 양적인 수치를 계산하였고, 표와 그래프로 시각적인 분석하여 결과를 도출하였으며 이를 바탕으로 논의와 결론을 도출하였다. 이를 요약하면 첫째, 마음챙김기반 읽기중재는 학습장애 학생의 과제회 피성 행동이 감소되었고 주의집중행동을 향상시키는 효과가 있었으며, 둘째, 마음챙김기반 읽기중재는 학습장애 학생의 읽기유창성의 읽기정확도와 읽기속도를 향상시키는 효과가 있었다. 그리고 본 연구 결과를 바탕으로 논의와 더불어 학습장애 학생을 위한 마음챙김기반 중재의 다양한 임상적 접근의 필요성을 시사점으로 제시하였다.
User-driven Software Development: Translator's Workbench - An Exemplar Case Study. (1993)

S.319-324
Functional convergence of gliP and aspf1 in Aspergillus fumigatus pathogenicity (2018)

PAS: periodic acid-Schiff; PBS: phosphate buffered saline; ROS: reactive oxygen species; TUNEL: terminal deoxynucleotidyl transferase dUTP nick-end labeling.
Feature Aligned Recurrent Network for Causal Video Object Detection (2019)

Recently, object detection in static images has achieved great success thanks to the application of deep convolutional neural networks. Nevertheless, extending object detectors from image to video is not trivial. Video object detection often suffers from deteriorated object appearances, such as motion blur, video defocus, rare poses or partial occlusion. This paper presents a novel end-to-end Feature Aligned Recurrent Network (FARN) for video object detection with the following two key modules. The first one is a motion guided feature alignment module, which aligns feature maps of past frames with that of the current frame using optical flow fields derived by a subnetwork. The second one is a spatial aware recurrent module, which consists of an attention unit to adaptively weight feature maps from different frames according to learned image quality, and a recurrent unit to leverage spatio-temporal coherence. FARN works causally in the sense that no future frame is used for object detection in the current frame. As evaluated on the ImageNet VID dataset, FARN demonstrated promising performance for causal video object detection compared to state-of-the-art non-causal detectors.
Gallager B LDPC Decoder with Transient and permanent errors (2013)

In this paper, the performance of a noisy Gallager B decoder used to decode regular LDPC codes is studied. We assume that the noisy decoder is subject to both transient processor errors and permanent memory errors. Due to the asymmetric nature of permanent errors, we model error propagation in the decoder via a suitable asymmetric channel. We then develop a density evolution type analysis on this asymmetric channel. The recursive expression for the bit error probability is derived as a function of the code parameters (node degrees), codeword weight, transmission error rate and the error rates of the permanent and the transient errors. Based on this analysis, we then derive the residual error of the Gallager B decoder for the regime where the transmission error rate and the processing error rates are small. In this regime, we further observe that the residual error can be well approximated by the sum of suitably combined transient errors and permanent errors, provided that the check node degree is large enough. Based on this insight we then propose and analyze a simple scheme for detecting permanent errors. The scheme exploits the parity check equations of the code itself and reuses the existing hardware to locate permanent errors in memory blocks. With high probability, the detection scheme discovers correct locations of permanent memory errors, while, with low probability, it mislabels the functional memory as being defective.
28 GHz wideband filter using quartz crystal waveguide for massive MIMO antenna unit (2017)

Massive MIMO technology and mm-wave band radio communication are effective solution of a high data rate for 5G. This paper presents a novel 28GHz wideband filter for those antenna units. To realize a wide fractional bandwidth of 10%, a new terminal configuration of “Y-shaped” structure is proposed. A TEM-TE mode transition function using the new structure was analyzed, and the shape was optimized. Applying the new terminal structure to an 8-pole with 2 trap quartz waveguide filter, high performances such as very low loss of 1.2 dB, wide relative passband of 10.4% and high attenuation of more than 50dB were obtained with a small size and SMD structure.
The effect of resuscitative endovascular balloon occlusion of the aorta, partial aortic occlusion and aggressive blood transfusion on traumatic brain injury in a swine multiple injuries model (2017)

In an animal model of TBI and shock, REBOA increased Qcarotid and pMAP, but did not exacerbate TBI progression. PAO resulted in physiology closer to baseline with smaller increases in ICP and pMAP. Rapid blood resuscitation, not REBOA, resulted in the largest increase in ICP after intervention, which occurred in Control animals. Continued studies of the cerebral hemodynamics of aortic occlusion and blood transfusion are required to determine optimal resuscitation strategies for multi-injured patients.
Patient Body Image and Satisfaction with Surgical Wound Appearance After Reduced Port Surgery for Colorectal Diseases (2016)

We find that RPS, especially SPS, enhances patient satisfaction by reducing abdominal wall trauma. This new advantage of RPS may prove valuable in its consideration as an option in laparoscopic colorectal surgery.
ChemInform Abstract: Photosensitive Tetramethylpiperidine Urethanes: Synthesis and Characterization. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Classifying emotions in human-machine spoken dialogs (2003)

This paper reports on the comparison between various acoustic feature sets and classification algorithms for classifying spoken utterances based on the emotional state of the speaker. The data set used for the analysis comes from a corpus of human-machine dialogs obtained from a commercial application. Emotion recognition is posed as a pattern recognition problem. We used three different techniques - linear discriminant classifier (LDC), k-nearest neighborhood (k-NN) classifier, and support vector machine classifier (SVC) -for classifying utterances into 2 emotion classes: negative and non-negative. In this study, two feature sets were used; the base feature set obtained from the utterance-level statistics of the pitch and energy of the speech, and the feature set analyzed by principal component analysis (PCA). PCA showed a performance comparable to the base feature sets. Overall, the LDC achieved the best performance with error rates of 27.54% on female data and 25.46% on males with the base feature set. The SVC, however, showed a better performance in the problem of data sparsity.
Development and HIL Testing of a Protection System for the Application of 154-kV SFCL in South Korea (2019)

In South Korea, a 154-kV single-phase superconducting fault current limiter (SFCL) system was developed and installed at the Gochang power test center of Korea Electric Power Corporation in 2016. Korea Electrotechnology Research Institute proposed a novel protection algorithm for the application of 154-kV SFCLs to a real power system and designed a protection scheme of the Gochang power test center. This paper verified the protection scheme using the hardware in the loop testing that a commercial protective relay system with the novel algorithm is tested by real time digital simulator.