gebhart/patrepeval huggingface dataset:
Values and gender peculiarities of advertising texts in french, english and russian (2018)

The article deals with the linguistic analysis of French, English and Russian magazine advertisements in order to estimate the specificities of the advertising genre and values in the three different cultural and linguistic systems. Before writing this article, we conducted a comparative study of the texts of the advertising discourse in English, French and Russian with the purpose of revealing the gender and value features of the advertising text. The choice of this topic is determined by the leading role of advertising in the life of modern societies, its genre diversity, and the development of sociolinguistic approaches to the study of modern language processes. The need to study the specifics of the advertising text also arises in connection with the differentiated treatment of advertising to different categories of recipients. Particularly there is differentiation of advertising depending on its focus on male or female audiences. This is manifested not only in the presentation of the advertised product, but also in the choice of specific language material, depending on the gender and value orientation of advertising.
High Mobility Titanium-doped Indium Oxide for Use in Tandem Solar Cells Deposited via Pulsed DC Magnetron Sputtering (2014)

The effects of pulsed DC (PDC) magnetron sputtering on the crystalline structure of the high mobility transparent conducting oxide (TCO), titanium-doped indium oxide (ITiO), are investigated. High mobility (μ >100 V-1s-1cm2) ITiO films are deposited by PDC magnetron sputtering and compared to RF deposited films using optimized conditions. These high mobility ITiO films have shown to extend the transmission in the NIR region compared to typical TCOs, such as ITO, exhibiting their potential in a tandem or multiple junction solar cell application. ITiO films deposited by PDC magnetron sputtering offer an increased deposition rate without a significant reduction in mobility when compared to RF sputtering, thus potentially offering PDC as a preferred industrial choice over RF sputtering. Structural characterization of the ITiO films prepared by PDC show a change in crystalline orientation and crystallite shape when compared to RF films, measured by XRD and SEM, which have been linked with the electrical parameters of the TCO.
Development of machine learning algorithms to estimate maximum residue limits for veterinary medicines (2023)

Establishing maximum-residue limits (MRLs) for veterinary medicine helps to protect the human food supply. Guidelines for establishing MRLs are outlined by regulatory authorities that drug sponsors follow in each country. During the drug approval process, residue limits are targeted for specific animal species and matrices. Therefore, MRLs are commonly not established for other species. This study demonstrates unestablished MRLs can be reliably predicted for under-represented food commodity groups using machine learning (ML). Classification methods with imbalanced data were used to analyze MRL data from multiple countries by implementing resampling techniques in different ML classifiers. Afterward, we developed and evaluated a data-mining method for predicting unestablished MRLs. Seven different ML classifiers such as support vector classifier, multi-layer perceptron (MLP), random forest, decision tree, k-neighbors, Gaussian NB, and AdaBoost have been selected in this baseline study. Among these, the neural network MLP classifier reliably scored the highest average-weighted F1 score (accuracy >99% with markers and ≈88% without markets) in predicting unestablished MRLs. This provides the first study to apply ML algorithms in regulatory food animal medicine. By predicting and estimating MRLs, we can potentially decrease the use and cost of live animals and the overall research burden of determining new MRLs.
Related binding mechanisms for fibrinogen, fibronectin, von Willebrand factor, and thrombospondin on thrombin-stimulated human platelets (1985)

Fibrinogen, fibronectin, von Willebrand factor, and thrombospondin are four large glycoproteins that bind to thrombin-stimulated platelets and influence cellular adhesive functions. The effects of five monoclonal antibodies that react with platelet membrane glycoproteins (GP) IIb and/or IIIa on the binding of these four molecules to stimulated platelets were assessed. Tab and PMI-1, antibodies recognizing GPIIb, had no effect, whereas 10E5 and 2G12, antibodies that immunoprecipitate both GPIIb and IIIa in the presence of calcium, inhibited binding of all four ligands by greater than 85%. T10, an antibody specific for the GPIIb-IIIa complex, produced partial inhibition (60% to 80%) of the binding of each ligand. Inhibitory antibodies were effective in the same dose range for all four proteins and also inhibited binding of fibrinogen, fibronectin, and von Willebrand factor to receptors fixed in an induced state (thrombin-stimulated platelets fixed with paraformaldehyde). Thrombospondin did not bind to these fixed cell preparations. The results suggest that these four adhesive proteins have a related mechanism of binding to thrombin-stimulated platelets. This related mechanism may entail the sharing of some, but not necessarily all, binding sites for the four ligands or a proximal relationship between these binding sites.
Adenosine A2A Receptor: A New Neuroprotective Target in Light-Induced Retinal Degeneration (2022)

Continuous illumination induces the degeneration of photoreceptors. This animal model of light-induced retinal degeneration resembles many characteristics of human degenerative diseases of the outer retina, such as age-related macular degeneration. This work aimed to evaluate the potential neuroprotective effect of the modulation of adenosine A2A receptor in the model of light-induced retinal degeneration. Sprague-Dawley rats were intravitreally injected in the right eye with either CGS 21680, an adenosine A2A receptor agonist, or SCH 58261, an adenosine A2A receptor antagonist. Contralateral eyes were injected with respective vehicles as control. Then, rats were subjected to continuous illumination (12,000 lux) for 24 h. Retinas were processed by glial fibrillary acidic protein (GFAP) immunohistochemistry, terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) technique, Western blotting (WB), and quantitative reverse transcription-polymerase chain reaction (qRT-PCR). Another group of rats was subjected to functional studies by electroretinography. Animals treated with CGS21680 showed a significant increase of apoptotic nuclei in the outer nuclear layer and a significant increase of GFAP immunoreactive area of the retinas but did not alter WB nor electroretinography results. qRT-PCR showed that CGS 21680 significantly increased the expression of interleukin-1β. On the opposite, SCH 58261 significantly decreased apoptotic nuclei in the outer nuclear layer and GFAP immunoreactive area of the retinas. It also significantly decreased GFAP and activated caspase-3 levels as measured by WB and preserved retinal function, as treated eyes showed significantly greater amplitudes of a- and b-waves and oscillatory potentials. qRT-PCR revealed that SCH 58261 significantly decreased the expression of tumor necrosis factor-α. These results show that the blockade of the A2A receptor before the start of the pathogenic process is neuroprotective, as it prevents light-induced retinal damage. The use of A2A receptor antagonists deserves to be evaluated in retinal degenerative diseases.
Clinical Relevance of Immunobiology in Umbilical Cord Blood Transplantation (2019)

Umbilical cord blood transplantation (UCBT) has been an important donor source for allogeneic hematopoietic stem cell transplantation, especially for patients who lack suitable matched donors. UCBT provides unique practical advantages, such as lower risks of graft-versus-host-disease (GVHD), permissive HLA mismatch, and ease of procurement. However, there are clinical challenges in UCBT, including high infection rates and treatment-related mortality in selected patient groups. These clinical advantages and challenges are tightly linked with cell-type specific immune reconstitution (IR). Here, we will review IR, focusing on T and NK cells, and the impact of IR on clinical outcomes. Better understanding of the immune biology in UCBT will allow us to further advance this field with improved clinical practice.
Purification and Properties of Undecyl Acetate Esterase from Pseudomonas cepacia Grown on 2-Tridecanone (1974)

Undecyl acetate esterase has been purified from Pseudomonas cepacia grown on the methyl ketone, 2-tridecanone. The K(m) for undecyl acetate was 2.3 x 10(-2) M. Polyacrylamide gel electrophoresis indicated that two esterase bands were being recovered during purification. These bands were separated by preparative polyacrylamide gel electrophoresis. Molecular weights were estimated to be approximately 34,500 by several methods. Molecular sieve polyacrylamide gel electrophoresis indicated that the two esterases had the same molecular weight but different charge, which is indicative of isoenzymes.
Radiation Damage Suppression in AISI-316 Steel Nanoparticles: Implications for the Design of Future Nuclear Materials (2020)

The self-healing capability of point and extended defects that are introduced by energetic particle irradiation is a desired behavior to be attained in the design and selection in potential materials for application in extreme environments. Nanoporous materials have a potential for achieving higher radiation tolerance due to the presence of many active unsaturable surfaces to which defects may diffuse and thus be effectively annihilated. The effects of heavy ion collisions in the lattice of functional AISI-316 steel nanoparticles (NPs)—which serve as a model for the ligaments in a nanoporous—are herein investigated in situ within a transmission electron microscope. Comparisons are made directly with AISI-316 steel in the form of foils, and the results show that the fewer radiation-induced defect clusters form in the NPs and that small NPs (r &lt; 50 nm) were observed to accumulate fewer defects when compared to larger NPs. Post-irradiation analytical characterization within a scanning transmission electron microscope revealed that the AISI-316 steel NPs may develop a radiation-induced self-passivation driven by a solute-drag mechanism: an effect that can potentially enhance their radiation corrosion resistance in the expected extreme conditions of a reactor. The capability of an NP to self-heal irradiation-induced point defects is investigated using the cellular model for active internal and surface sinks. The design of functional nanoscale materials for extreme environments is discussed.
In vivo 1H NMR spectroscopy of the human brain at 7 T (2001)

In vivo 1H NMR spectra from the human brain were measured at 7 T. Ultrashort echo-time STEAM was used to minimize J-modulation and signal attenuation caused by the shorter T2 of metabolites. Precise adjustment of higher-order shims, which was achieved with FASTMAP, was crucial to benefit from this high magnetic field. Sensitivity improvements were evident from single-shot spectra and from the direct detection of glucose at 5.23 ppm in 8-ml volumes. The linewidth of the creatine methyl resonance was at best 9 Hz. In spite of the increased linewidth of singlet resonances at 7 T, the ability to resolve overlapping multiplets of J-coupled spin systems, such as glutamine and glutamate, was substantially increased. Characteristic spectral patterns of metabolites, e.g., myo-inositol and taurine, were discernible in the in vivo spectra, which facilitated an unambiguous signal assignment.
Synthesis of Thermogelling Poly(N-isopropylacrylamide)-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering (2016)

Injectable biomaterials are defined as implantable materials that can be introduced into the body as a liquid and solidify in situ. Such materials offer the clinical advantages of being implanted minimally invasively and easily forming space-filling solids in irregularly shaped defects. Injectable biomaterials have been widely investigated as scaffolds for tissue engineering. However, for the repair of certain load-bearing areas in the body, such as the intervertebral disc, scaffolds should possess adhesive properties. This will minimize the risk of dislocation during motion and ensure intimate contact with the surrounding tissue, providing adequate transmission of forces. Here, we describe the preparation and characterization of a scaffold composed of thermally sensitive poly(N-isopropylacrylamide)-graft-chondroitin sulfate (PNIPAAM-g-CS) and alginate microparticles. The PNIPAAm-g-CS copolymer forms a viscous solution in water at RT, into which alginate particles are suspended to enhance adhesion. Above the lower critical solution temperature (LCST), around 30 °C, the copolymer forms a solid gel around the microparticles. We have adapted standard biomaterials characterization procedures to take into account the reversible phase transition of PNIPAAm-g-CS. Results indicate that the incorporation of 50 or 75 mg/ml alginate particles into 5% (w/v) PNIPAAm-g-CS solutions quadruple the adhesive tensile strength of PNIPAAm-gCS alone (p<0.05). The incorporation of alginate microparticles also significantly increases swelling capacity of PNIPAAm-g-CS (p<0.05), helping to maintain a space-filling gel within tissue defects. Finally, results of the in vitro toxicology assay kit, 2,3-bis-(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide (XTT) and Live/Dead viability assay indicate that the adhesive is capable of supporting the survival and proliferation of encapsulated Human Embryonic Kidney (HEK) 293 cells over 5 days.
Evaluation of flexible postconsumed polyurethane foams modified by polystyrene grafting as sorbent material for oil spills (2008)

Abstract This work studies the possibility of reusing flexible postconsumed polyurethane foams modified by grafting with polystyrene as a sorbent material for the mitigation of oil spills. Different foams were evaluated via crude oil sorption and retention experiments, density, and morphological analyses. The foams with the best performance were chemically modified by grafting with polystyrene under different conditions (initiator concentration, styrene volume, and reaction time) in a system initiated by oxi‐reduction of Ce(IV) from an amoniacal ceric nitrate solution. A three‐level factorial design was used to study the influence of the variables. The foams were characterized via spectroscopy (XPS/ESCA and infrared) and water and oil sorption. Foam modification via grafting with polystyrene showed to be a viable alternative to increase its oil sorption ability. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2009
Synthesis and Characterization of New Chiral Side Chain Liquid Crystalline Polyoxetanes (2000)

Two series of the side chain liquid crystalline polyoxetanes were synthesized via cationic ring-opening polymerization of oxetane monomers bearing pendant mesogenic units including two chiral carbons. The first two polymers have only one pendant group in the repeating unit, whereas the second polymers have two mesogenic groups per repeating unit. The oxetane monomer bearing one mesogenic unit produced high molecular weight polymers, whereas the ones bearing two mesogenic units at the same carbon in the ring produced only oligomeric products. Thermal and liquid crystalline properties of the polymers were investigated by optical polarizing microscopy, differential scanning calorimetry (DSC), and small- and wide-angle X-ray diffractometry. All of the polymers, with the exception of only one polymer, formed liquid crystalline phases such as SA, SC*, and SI* phases in melts. The molecular arrangement in the smectic phases was interpreted as an intercalated bilayer structure. An attempt to study the ferroelectric properties of the polymers was made, but the results obtained were not satisfactory.
DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential (2022)

Cells with latent stem ability can contribute to mammalian tissue regeneration after damage. Whether the central nervous system (CNS) harbors such cells remains controversial. Here, we report that DNGR-1 lineage tracing in mice identifies an ependymal cell subset, wherein resides latent regenerative potential. We demonstrate that DNGR-1-lineage-traced ependymal cells arise early in embryogenesis (E11.5) and subsequently spread across the lining of cerebrospinal fluid (CSF)-filled compartments to form a contiguous sheet from the brain to the end of the spinal cord. In the steady state, these DNGR-1-traced cells are quiescent, committed to their ependymal cell fate, and do not contribute to neuronal or glial lineages. However, trans-differentiation can be induced in adult mice by CNS injury or in vitro by culture with suitable factors. Our findings highlight previously unappreciated ependymal cell heterogeneity and identify across the entire CNS an ependymal cell subset wherein resides damage-responsive neural stem cell potential.
Irrigation of the Maxillary Sinus by Canine Fossa Puncture: Experience with 202 Patients (1983)

Maxillary sinus lavage through the canine fossa was performed on 202 patients. This procedure is relatively safe, easily learned and quickly performed, has minimal side effects and a very low percentage of failures, and is more acceptable to most patients. It should be used by otolaryngologists, at least as a useful alternative to the classical method.
The ICDT 2016 Test of Time Award Announcement (2016)

We describe the 2016 ICDT Test of Time Award which is awarded to Chandra Chekuri and Anand Rajaraman for their 1997 ICDT paper on "Conjunctive Query Containment Revisited".
Integrated Catheter Care Pathway Package (ICCPP) regarding indwelling urinary catheter care on knowledge among staff nurses in a selected hospital at Mangalore (2014)

The urinary tract infection is frequent in hospital environment and normally associated with the instrumentation of the urinary tract. Use of indwelling urinary catheters can lead to complications, most commonly catheter-associated urinary tract infections. This study attempts to evaluate the effectiveness of “Integrated Catheter Care Pathway Package (ICCPP)” regarding indwelling urinary catheter care on knowledge of staff nurses. Data was collected from 50 nurses; the results showed ICCPP was effective in increasing the knowledge of staff nurses regarding indwelling urinary catheter care.
22mJ Coherent Beam Combining from Three 85μm Core CCC Fiber Amplifiers (2021)

We demonstrate coherent beam combining of pulses from 3 chirally-coupled core optical fibers into a single 22mJ pulse, achieving &gt;7mJ per channel combining and allowing for future temporal combination and compression at high energy.
ChemInform Abstract: One‐Pot Cyclization of Epoxy Olefins to Substituted Cycloalkanols via Free Radicals. (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Organic Phosphates. VI. Alcoholysis of Catechol Cyclic Phosphates. (1). (1959)

Catechol cyclic phosphate (CCP) (IV) was found to be alcoholyzed with several primary and secondary monofunctional alcohols to give the corresponding alkyl or aralkyl ohydroxyphenyl phosphate (V) in a yield of 47∼65%. These reactions proceeded by the catalytic function of the acid reagent, CCP, used. The products (V) were further hydrolyzed by acid or alkali to give the corresponding alcohols and o-hydroxyphenyl phosphate. The catechol moiety of (V) was found inert against catalytic hydrogenolysis, while it was hydrolyzed by snake venom phosphodiesterase to alkyl or aralkyl phosphates.
DNA ASSOCIATED WITH THE CELL MEMBRANE IS INVOLVED IN THE INHIBITION OF THE SKIN REJECTION RESPONSE INDUCED BY INFUSIONS OF PHOTODAMAGED ALLOREACTIVE CELLS THAT MEDIATE REJECTION OF SKIN ALLOGRAFT (1992)

Cell membrane DNA (cmDNA) is a form of DNA located on the surface of human and murine T-cells. It has recently been characterized as a target for photomodification by 8-methoxypsoralen (8-MOP) and long-wave ultraviolet light (UV-A). Whereas 8-MOP itself is biologically inert, photoactivated 8-MOP is covalently bound to pyrimidine bases in DNA. We have investigated the possible involvement of cmDNA photomodification in the induction of the suppression of skin allograft rejection in BALB/c mice preimmunized with 8-MOP/UV-A photodamaged alloreactive cells which mediates this allograft rejection. This suppression is demonstrated by inhibition of delayed-type hypersensitivity (DTH) and mixed leukocyte culture (MLC) responses. Splenocytes from BALB/c mice undergoing rejection of CBA/j skin graft which contained an expanded population of the effector T lymphocytes that mediate the rejection were treated with DNAse to remove cmDNA before or after treatment with 8-MOP and UV-A prior to infusion into naive BALB/c recipients. Mice that received pretreated effector cells were tested for MLC responses to CBA/j or B10 alloantigens before and after the DTH response. The DTH response of all groups of pretreated BALB/c mice to the relevant alloantigen was specifically suppressed as compared with the response of control mice. However, adoptive transfer of the suppression of the DTH response was optimally demonstrable only in syngeneic recipients of cells from donor mice treated with photodamaged alloreactive cells. Also, splenocytes from BALB/c mice immunized with photodamaged alloreactive cells demonstrated highly significant hyporesponsiveness and suppression of the MLC response of naive mice to the relevant alloantigen in the case of the primary MLC response, and to both alloantigens in the secondary MLC response which was totally eliminated by prior pretreatment of these effector cells with DNAse. Therefore, it appears that the suppression of the DTH response can be induced by pretreatment of the effector cells with DNAse and/or 8-MOP and UV-A but is adoptively transferable optimally only from mice which are recipients of photodamaged alloreactive cells. Moreover, the effectiveness of this treatment is decreased by prior removal of cmDNA from these cells. The presence of cmDNA is necessary for induction of suppression of the primary and secondary MLC responses in mice treated with photodamaged cells of allograft rejection.