gebhart/patrepeval huggingface dataset:
Energy-Aware Migration of Virtual Machines Driven by Predictive Data Mining Models (2015)

Consolidation of virtual machines (VM) is one of the key strategies used to reduce the power consumption of Cloud servers. For this reason it is extensively studied. Nevertheless, the effectiveness of a consolidation strategy strongly depends on the forecast of the VM resource needs. This paper describes the design and development of a system for energy-aware allocation of virtual machines, driven by predictive data mining models. In particular, migrations are driven by the forecast of the future computational needs (CPU, RAM) of each virtual machine, in order to efficiently allocate those on the available servers. Experimental results, performed on data of a real Cloud data centre, show encouraging benefits in terms of energy saving.
A cryogen-free superconducting magnet based scanning tunneling microscope for liquid phase measurement (2023)

Scanning tunneling microscopes (STMs) that work in ultra-high vacuum and low temperatures are commonly used in condensed matter physics, but an STM that works in a high magnetic field to image chemical molecules and active biomolecules in solution has never been reported. Here, we present a liquid-phase STM for use in a 10 T cryogen-free superconducting magnet. The STM head is mainly constructed with two piezoelectric tubes. A large piezoelectric tube is fixed at the bottom of a tantalum frame to perform large-area imaging. A small piezoelectric tube mounted at the free end of the large one performs high-precision imaging. The imaging area of the large piezoelectric tube is four times that of the small one. The high compactness and rigidity of the STM head make it functional in a cryogen-free superconducting magnet with huge vibrations. The performance of our homebuilt STM was demonstrated by the high-quality, atomic-resolution images of a graphite surface, as well as the low drift rates in the X-Y plane and Z direction. Furthermore, we successfully obtained atomic-resolution images of graphite in solution conditions while sweeping the field from 0 to 10 T, illustrating the new STM's immunity to magnetic fields. The sub-molecular images of active antibodies and plasmid DNA in solution conditions show the device's capability of imaging biomolecules. Our STM is suitable for studying chemical molecules and active biomolecules in high magnetic fields.
Measuring mixed signal substrate coupling (2002)

A measurement method is proposed to characterise the substrate coupling between digital and analog sections of a mixed signal CMOS chip. Induced noise and spurious signals are measured by a custom designed analog sensor. Calibrated sampling scope based measurements show the strength and drawbacks of the proposed approach.
Quantum reservoir neural network implementation on a Josephson mixer (2022)

Quantum reservoir computing is a promising approach to quantum neural networks capable of solving hard learning tasks on both classical and quantum input data. However, current approaches with qubits are limited by low connectivity. We propose an implementation for quantum reservoir that obtains a large number of densely connected neurons by using parametrically coupled quantum oscillators instead of physically coupled qubits. We analyse a specific hardware implementation based on superconducting circuits. Our results give the coupling and dissipation requirements in the system and show how they affect the performance of the quantum reservoir. Beyond quantum reservoir computation, the use of parametrically coupled bosonic modes holds promise for realizing large quantum neural network architectures.
Molecular cartography of globular proteins with application to antigenic sites (1986)

Abstract A method, molecular cartography, is introduced as a way to quantitate the topographic structure of a protein surface. The method is applied to the problem of antigenic determinants, and it is used to examine local and global topography of reported antigenic regions on the surface of myoglobin and lysozyme. In nine antigenic sites taken from the literature and studied in detail, no local property was found in sites that was not also found in remaining regions of the surface. However, a strong correlation was found between antigenic sites and regions of the surface that are globally exposed. This finding suggests that global exposure of the protein surface may play a primary role in determining the antigenic structure of the protein. Molecular cartography may be useful in other instances of protein–protein interactions such as those between proteolytic enzymes and their substrates.
Improvement of sleep apnoea due to acromegaly during short‐term treatment with octreotide (1994)

Two acromegalic patients suffering from severe obstructive sleep apnoea syndrome were treated with the long-acting somatostatin analogue octreotide. Daytime sleepiness and fatigue improved within a few days. Repeat sleep studies performed after octreotide treatment revealed more confluent sleep with a shorter duration of sleep apnoea. Nocturnal hypoxaemia improved in one patient. Octreotide might be an effective noninvasive treatment for sleep apnoea of acromegaly.
ASIE: application-specific image enhancement for face recognition (2013)

In this paper, we propose a novel method to enhance low quality images. Specifically, we focus on facial images. Low quality images are often degraded by motion artifacts, sensor limitations, and noise contamination leading to loss of higher order information that is essential for face recognition. First, we demonstrate that conventional denoising and deblurring methods are not able to fully recover the latent image resulting in residual artifacts in the image. Then, we present a novel approach for image enhancement that removes these residual artifacts using sparse encoding methods. The potential of the method is demonstrated through promising results on facial images for face recognition application.
Preparation and Physical Properties of EuC2 and Its Solid Solutions, RxEu1−xC2 (R=La and Gd) (1982)

Abstract A cubic-tetragonal phase transformation of EuC2 was observed at 623 K. The phase transition temperatures of metal dicarbides (MC2) were discussed in terms of the band structure proposed by previous authors. The compound EuC2 was a ferromagnet with a zero field curie temperature of 20 K, which was close to the value expected from the Curie temperature vs. nearest neighbor Eu–Eu distance relation for the Eu chalcogenides. The solid solutions, LaxEu1−xC2, became ferromagnetic at low temperatures over the whole composition range, while the solid solutions, GdxEu1−xC2, have continuously changed the kind of magnetic order from ferromagnetic to antiferromagnetic. All the effective moments obtained for RxEu1−xC2 were in good agreement with the theoretical values of Eu2+ and R3+ contained. The electrical resistivities of EuC2 and its solid solutions had a sharp peak near the Curie temperature. When magnetic field was applied, the peak became broader and shifted to higher temperature.
High-resolution mapping of phase-matching conditions in second-order nonlinear crystals (2022)

We demonstrate the spatial mapping of phase-matching conditions in nonlinear crystals using detuned second-harmonic generation. A beam-stabilization system cancels out the angular wobbling of the translation stages that scan the crystal under test in front of the static probe beam at the fundamental frequency. A submillimeter resolution over the full scanned aperture, 50 × 50 mm 2 , is demonstrated. The mapping of several partially deuterated potassium dihydrogen phosphate (DKDP) crystals reveals the spatially nonuniform phase-matching conditions due to internal variations in crystal properties and high-frequency surface variations.
Realizing Policy Roaming by Cooperating Edge-Mobility and Authentication Systems (2008)

In recent years, the wireless roaming infrastructure has been deployed in many organizations. The eduroam is one of the wireless roaming infrastructures which realize international roaming by cooperating hierarchically structured user authentication systems. However, the guest userpsilas IP address assigned is the foreign organizations then the network access of the guest users may be restricted. In this paper, we propose a network access control mechanism which makes users' network access transparently while following the policies of their organizations even when they visit other organizations. We call this feature the policy roaming.
TLR: A Traffic-Light-Based Intelligent Routing Strategy for NGEO Satellite IP Networks (2014)

We present TLR, a traffic-light-based intelligent routing strategy for NGEO satellite IP networks. In TLR, a set of traffic lights are used to indicate the congestion status at both the current node and the next node. When a packet travels along a pre-calculated route to the destination, it may adjust the route dynamically, according to the real-time color of traffic lights at each intermediate node. Through the combination of preliminary planning and real-time adjustment, each packet can eventually get an approximately optimal transmission path. The multi-path routing mechanism in TLR can help achieve a good distribution of traffics when the network traffic increases. The Public Waiting Queue scheme in TLR can fully utilize free spaces of the buffer queues and lower the packet drop rate. While the concept of TLR has many advantages, it may result in endless-loop of routing. To eliminate this phenomenon, a defense scheme is incorporated in the design of TLR. A set of simulations are conducted using the Network Simulator (version 2) to verify the good performance of TLR, in terms of lower packet drop rate, better distribution of traffics and higher throughput, over the entire satellite constellation.
Anomalous Spontaneous Reversal in Magnetic Heterostructures (2006)

This papers present a novel phenomenon in FM/AF heterostructure systems (AF = FeF <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> , FM= (Ni,Co)), where the FM switching can be also controlled by thermal cycling. It was found that a FM saturated above the AF Neel temperature T <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">N</sub> , spontaneously reverses its magnetization against a constant field with decreasing temperature. This reversal also exhibits a significant magnetization vs. temperature hysteresis, with a tunable height and width by the field. This is reminiscent of the conventional magnetization hysteresis and enables one to control the FM switching by thermal cycles, and may have implication on the thermally assisted magnetic recording.
Bonding of beam lead integrated circuits (1967)

The development of the sealed-junction, beam-lead silicon integrated circuit permits new freedom in the assembly of complex functional circuits. Because of the intrinsic capabilities of this silicon device technology, handling, registering, and bonding techniques which are capable of achieving high yields at manufacturable rates are being developed. For the device, the beams are utilized as the prime elements for handling and registration of the chip to the pattern of conductors on a substrate. Requirements and procedures for these operations, are briefly described.
The Effector Domain of Human Dlg Tumor Suppressor Acts as a Switch That Relieves Autoinhibition of Kinesin-3 Motor GAKIN/KIF13B (2007)

The activity of motor proteins must be tightly regulated in the cells to prevent unnecessary energy consumption and to maintain proper distribution of cellular components. Loading of the cargo molecule is one likely mechanism to activate an inactive motor. Here, we report that the activity of the kinesin-3 motor protein, GAKIN, is regulated by the direct binding of its protein cargo, human discs large (hDlg) tumor suppressor. Recombinant GAKIN exhibits potent microtubule gliding activity but has little microtubule-stimulated ATPase activity in solution, suggesting that it exists in an autoinhibitory form. In vitro binding measurements revealed that defined segments of GAKIN, particularly the MAGUK binding stalk (MBS) domain and the motor domain, mediate intramolecular interactions to confer globular protein conformation. Direct binding of the SH3-I3-GUK module of hDlg to the MBS domain of GAKIN activates the microtubule-stimulated ATPase activity of GAKIN by approximately 10-fold. We propose that the cargo-mediated regulation of motor activity constitutes a general paradigm for the activation of kinesins.
Uterine neoplasms: MR imaging. (1986)

Magnetic resonance (MR) studies were performed on 20 healthy volunteers and 41 patients with proved cervical and uterine neoplasms. MR imaging demonstrated normal uterine landmarks in all patients. On T2-weighted images, the normal uterine wall could be differentiated into three distinct layers: a central high-intensity zone, a junctional low-intensity band, and a peripheral medium-intensity area. While most of the normal cervices had only two distinct zones (central high-intensity zone and peripheral low-intensity zone), a small percentage had three layers of signal intensity, similar to the uterine body. Primary cervical and uterine neoplasms could be identified on MR images. In 18 of 22 patients with proved carcinoma, a mass with a signal intensity higher than that of normal cervical lips was seen on T2-weighted images. Endometrial carcinoma was most often identified as expansion of the central high-intensity area; discrete tumor nodules were visible in nine of 15 patients. Mixed müllerian sarcoma appeared as a large pelvic mass with complete obliteration of normal uterine landmarks. MR imaging delineates primary cervical and endometrial carcinoma better than computed tomography does.
Specific Gene Silencing by Artificial MicroRNAs in Physcomitrella patens: An Alternative to Targeted Gene Knockouts (2008)

MicroRNAs (miRNAs) are approximately 21-nucleotide-long RNAs processed from nuclear-encoded transcripts, which include a characteristic hairpin-like structure. MiRNAs control the expression of target transcripts by binding to reverse complementary sequences directing cleavage or translational inhibition of the target RNA. Artificial miRNAs (amiRNAs) can be generated by exchanging the miRNA/miRNA* sequence within miRNA precursor genes, while maintaining the pattern of matches and mismatches in the foldback. Thus, for functional gene analysis, amiRNAs can be designed to target any gene of interest. The moss Physcomitrella patens exhibits the unique feature of a highly efficient homologous recombination mechanism, which allows for the generation of targeted gene knockout lines. However, the completion of the Physcomitrella genome necessitates the development of alternative techniques to speed up reverse genetics analyses and to allow for more flexible inactivation of genes. To prove the adaptability of amiRNA expression in Physcomitrella, we designed two amiRNAs, targeting the gene PpFtsZ2-1, which is indispensable for chloroplast division, and the gene PpGNT1 encoding an N-acetylglucosaminyltransferase. Both amiRNAs were expressed from the Arabidopsis (Arabidopsis thaliana) miR319a precursor fused to a constitutive promoter. Transgenic Physcomitrella lines harboring the overexpression constructs showed precise processing of the amiRNAs and an efficient knock down of the cognate target mRNAs. Furthermore, chloroplast division was impeded in PpFtsZ2-1-amiRNA lines that phenocopied PpFtsZ2-1 knockout mutants. We also provide evidence for the amplification of the initial amiRNA signal by secondary transitive small interfering RNAs, although these small interfering RNAs do not seem to have a major effect on sequence-related mRNAs, confirming specificity of the amiRNA approach.
Effects of vif Mutations on Cell-Free Infectivity and Replication of Simian Immunodeficiency Virus (1994)

To investigate the function of the Vif protein of the simian immunodeficiency virus (SIV), mutations were introduced into the SIVmac239 vif gene without affecting the reading frames of other overlapping genes. The phenotypes of these mutant viruses were examined with respect to viral replication and the expression and processing of viral proteins. Transfection of vif-mutant proviral DNA into established T cell lines resulted in a significant delay in the onset of virus replication compared to that seen with the wild-type provirus. The efficiency of replication of the vif-mutant virus was dependent on cell type. MT-4 cells were permissive for replication of the vif mutant, while replication in CEMx174 cells was severely restricted. Little or no virus replication was observed following cell-free infection of the CEMx174 cell line and macaque peripheral blood mononuclear cells (PBMC). These results indicate that the requirement for vif during the replication of SIVmac239 is dependent on cell type, as has been observed for HIV-1. Following cell-free infection, mutant viruses containing combined deletions in vif and the other regulatory genes (vpx, vpr, and nef) displayed replication kinetics similar to that of viruses containing the deletion of vif alone. Viral protein expression and processing in MT-4 cells of vif-deleted viruses were indistinguishable from those of the wild-type virus. The effects of two different point mutations in vif were examined. One point mutant in vif reverted to the genetic sequence of the wild-type virus within 2 weeks.2 +
Study on correlation of different levels of meningioma and matrix metalloproteinase-9 (2017)

Objective
Meningioma of intracranial tumors is one of the common benign tumor of neurosurgery. The study has in contrast of the different levels of meningiomas magnetic resonance imaging (MRI) features matrix metalloproteinase (MMP)-9 expression, further study of the different meningioma MRI and molecular pathological basis.


Methods
60 patients after surgical treatment had been confirmed by pathology. 34 cases of meningioma grade Ⅰ, 17 cases of meningiomas grade Ⅱ, 9 cases of meningiomas grade Ⅲ. Using superconducting 3.0 T magnetic resonance imaging system underwent MRI plain and enhanced scan. Using of immunohistochemistry to detect meningiomas of MMP-9 expression.


Results
Positive expression of 34 cases of Word Health Organization (WHO) grade Ⅰ meningiomas was 8.82%, 31 cases were negative, 2 cases had weak expression, and 1 case had neutral expression; Positive expression of 17 cases of WHO grade Ⅱ meningioma was 41.00%, 10 cases were negative, 5 cases had weak expression, and 2 cases had neutral expression; Positive expression of 9 cases of WHO grade Ⅲ meningiomas was 100.00%, and 9 cases had strong expression. Immunohistochemistry results show: the expression of MMP-9 significant difference (χ2=68.880, P=0.001) in all levels of meningiomas. meningiomas expression of grade Ⅲ was significantly higher statistically significant than grade Ⅱ (χ2=26.000, P=0.001), meningiomas expression of grade Ⅱ was significantly higher statistically significant than grade Ⅰ (χ2=7.550, P=0.023). Lowest expression in normal meningeal tissue, meningiomas expression of grade Ⅲ of MMP-9 expression in the highest, MMP-9 protein expression levels tended to increase with meningioma level increasing.


Conclusion
Meningiomas expression of grade III is the highest in expression of MMP-9. With meningioma level increases, MMP-9 expression corresponding increase. The meningioma high expression of MMP-9 promotes peritumoral brain edema formation, with a synergistic effect on tumor proliferation and infiltration.


Key words: 
Meningioma; Magnetic resonance imaging; Matrix metalloproteinase-9
Agrobacterium -mediated transformation of sugarcane using GFP as a screenable marker (1998)

The use of the green fluorescent protein (GFP) and in vivo screening for transgenic cells has enabled the first visual selection of transgenic sugarcane ( Saccharum L. hybrid) transformed by Agrobacterium -mediated techniques. Selection of GFP-positive embryogenic callus transformed using Agrobacterium tumefaciens strain AGL0 was performed by fluorescence microscopy for 6 weeks after transformation. The use of GFP as a screenable marker aided the rapid segregation of individual transformation events and facilitated the initial visual selection of transgenic sugarcane callus without antibiotics, herbicides or an assay. The binary vector used in transformation was pTO134, which contains a synthetic gfp gene ( sgfp S65T) and the bialaphos resistance gene ( bar ) both controlled by CaMV 35S promoters. The appearance of GFP-expressing cells observed on embryogenic callus was 5.3%. Subsequently, GFP-positive calli grew in the presence of a level of the herbicide bialaphos, that was toxic to untransformed calli. GFP-positive shoots were regenerated and one sugarcane plant expressed GFP in the initial stages. Molecular analysis confirmed the presence of the sgfp S65T coding region in the genome of regenerated plants. Visual screening for Agrobacterium -mediated transformation events using GFP was an efficient technique, which may be applied for the transformation of other plants.
Automated PRL measurements using a confocal laser ophthalmoscope (2001)

Ocular motility generated by various fixation strategies show a lower propensity to visit laser damaged retinal areas as compared to non-laser damaged sites. This selectivity provides a non-invasive methodology for characterizing retinal pathology by mapping eye movement visitation under various visual function fixation strategies. Ocular motor techniques for imaging eye movement maps of normal and damaged retinal regions are demonstrated with reference to retinal target location at the retina. Eye movement data digitized from a contrast sensitivity task provided video data of eye movement fixation patterns simultaneously with retmal location oftarget placement dunng periods of visual fixation required in a Landolt ring contrast sensitivity task. These data were digitized with specialized algorithms that linked target location with retmal morphology and pathology In one patient with central macular retmal damage, retmal based maps demonstrated strong consistency with measurements made with nonretina1 higher resolution Purkinje eye movement apparatus. Such eye movement maps differed primarily eye movement density within a given area but were generally comparable with respect focal areas mapped in retinal space. These data suggest that lower resolution video based imaging can provide a non-invasive assessment oflaser induced retinal damage.
Soluble poly(divinylbenzene): Reaction mechanism for the anionic polymerization of divinylbenzene with lithium diisopropylamide as catalyst (1986)

Abstract This paper presents results of the studies on the mechanism of initiation, propagation and chain transfer reactions in the recently found polymerization of 1,4‐ and/or 1,3‐divinylbenzene (DVB), initiated with lithium diisopropylamide/diisopropylamine. Initiation was confirmed to take place by addition reaction of the alkylamino group to the DVB molecule. The population of the triad tacticity of the soluble poly(DVB) suggested the steric course of the polymerization to proceed according to Bernoullian statistics with respect to the diad placements, m and r . The chain transfer reaction was found to take place via the free amine, the chain transfer reactivity of a primary amine being higher than that of a secondary amine. Comparative studies on the reactivity and selectivity of sodium diisopropylamide toward styrene and DVB were also carried out with respect to lithium diisopropylamide as reference.