gebhart/patrepeval huggingface dataset:
Serial transfer of isologous and homologous hematopoietic cells in irradiated hosts. (1961)

Isologous bone marrow and spleen cells were serially transplanted into x- irradiated (800 r) mice using various intervals and cell numbers. The degree of repopulation was estimated at each successive passage by counting the cells in suspensions prepared from femurs and spleens. With CBA males, 10/sup 6/ bone marrow cells were injected to establish the first passage. Seven days after transplantation the bone marrow was found to be partially regenerated and 1.3 x 10/sup 6/ of the cells were injected into irradiated second passage hosts. The second passage mice possessed only a very small number of cells per femur on day 7 and 1.1 x 10/sup 6/ cells/femur on day 14. The restorative capacity was low, which resulted in failure to establish the 3/sup rd/ passage. When the interval between passages was kept at about 14 days and the number of injected cells between 4.4 and 8.6 x 10/sup 6/, the line was carried successfully through 4 passages. The results suggest that the proliferation rate of the more primitive cell types is higher than that of the more mature ones, leading to a gradual shift in favor more » of the former when serial transfer is performed at short intervals. Longer intervals permit more time for maturation to take place. The favorable effect of increasing the periods between passages thus be obtained with a mixture of 9 to 17 x 10 spleen and marrow cells. C57BL cells were transferred through 4 passages of F/sub 1/(CBA x C57BL) hybrid mice. The results, obtained with a variety of experimental techniques, are suggestive of the development of a specific tolerance of the transferred cells toward the CBA tissue antigen. (TCO) « less
High-yield cell ordering and deterministic cell-in-droplet encapsulation using Dean flow in a curved microchannel (2012)

In this article high-yield (77%) and high-speed (2700 cells s(-1)) single cell droplet encapsulation is described using a Dean-coupled inertial ordering of cells in a simple curved continuous microchannel. By introducing the Dean force, the particles will order to one equilibrium position after travelling less than 1 cm. We use a planar curved microchannel structure in PDMS to spatially order two types of myeloid leukemic cells (HL60 and K562 cells), enabling deterministic single cell encapsulation in picolitre drops. An efficiency of up to 77% was reached, overcoming the limitations imposed by Poisson statistics for random cell loading, which yields only 37% of drops containing a single cell. Furthermore, we confirm that > 90% of the cells remain viable. The simple planar structure and high throughput provided by this passive microfluidic approach makes it attractive for implementation in lab on a chip (LOC) devices for single cell applications using droplet-based platforms.
Experimental assessment of a compact branched tray generator for ammonia–water desorption (2015)

AbstractAn experimental investigation of heat and mass transfer in a miniaturized ammonia–water desorber utilizing microscale geometries is presented. The desorber, sized for a 3.5-kW space-conditioning system, is of a branched tray design consisting of an array of alternating plates with integral microscale features enclosed between cover plates. The desorber is hydronically coupled to a heat transfer fluid that is heated by the combustion of natural gas. An adiabatic analyzer and solution cooled rectifier are integrated into the same envelope as the desorber. The component is tested as part of a single-pressure system on a breadboard test facility and is studied over a range of heat transfer fluid inlet temperatures, flow rates, and concentrated solution flow rates. Desorber performance is experimentally investigated over a wide range of test conditions to improve the understanding of performance at design and off-design conditions and the potential for flow instabilities.
First Documentation of Feather Fault Bars in the Northern Bobwhite (2019)

We examined 318 Colinus virginianus (Northern Bobwhite) wings from 27 Kentucky counties for fault bars. Fault bars are areas in flight feathers that lack pigment due to exposure to stressors. We detected fault bars on 38 (11.9%) wings (representing individual Northern Bobwhites) from 14 Kentucky counties; fault bars were most prevalent in juveniles. Fault bars have been documented on Phasianus colchicus (Ring-Necked Pheasant) and many species of passerine and raptorial birds, but this is the first report for the Northern Bobwhite. Examination of wings for fault bars could provide a new method for assessing stress in Northern Bobwhite populations and be useful to evaluate translocations or to select donor populations for translocation.
A reoptimization of the five-site water potential (TIP5P) for use with Ewald sums (2004)

The five-site transferable interaction potential (TIP5P) for water is most accurate at reproducing experimental data when used with a simple spherical cutoff for the long-ranged electrostatic interactions. When used with other methods for treating long-ranged interactions, the model is considerably less accurate. With small modifications, a new TIP5P-like potential can be made which is very accurate for liquid water when used with Ewald sums, a more physical and increasingly more commonly used method for treating long-ranged electrostatic interactions. The new model demonstrates a density maximum near 4 degrees C, like the TIP5P model, and otherwise is similar to the TIP5P model for thermodynamic, dielectric, and dynamical properties of liquid water over a range of temperatures and densities. An analysis of this and other commonly used water models reveals how the quadrupole moment of a model can influence the dielectric response of liquid water.
Securing DNS services through system self cleansing and hardware enhancements (2006)

Domain name systems (DNS) provide the mapping between easily-remembered host names and their IP addresses. Popular DNS implementations however contain vulnerabilities that are exploited by frequent, targeted attacks. The software vulnerabilities of DNS together with the constant innovation and morphing of cyber attack techniques necessitate the consideration of the worst case scenarios: there will be successful but undetected attacks against DNS servers. In this work, we develop a secure DNS architecture that contains the damage of successful, undetected attacks. This formidable end is achieved by constantly cleansing the servers and rotating the role of individual servers. Moreover, the server rotation process itself is protected against corruption by hardware. We will show the advantages of our design in the following areas: (1) protection of the DNS master file and cryptographic keys, (2) incorruptible intrusion tolerance, (3) high availability, and (4) scalability, the support of using of high degrees of hardware/server redundancy to improve both system security and service dependability. Due to the critical importance of DNS, such a dependable and intrusion-resilient design contributes significantly to the overall security of the Internet.
Ion exchange developments and applications : proceedings of IEX '96 (1996)

Water treatment ion exchange resins in nuclear power stations environmental and pollution control chelated heavy metals - recovery and separation form ligands nuclear adsorption and elution behaviour of platinum-group metals in nitric acid medium resin developments oxidation resistance of cation exchange resin fundamentals harmonization of ion exchange formulations and nomenclature inorganic materials sodium micas as cesium ion selective adsorbents hydormetallurgy kinetics of chromic acid removal by anion exchange separations anion resins and the law of mass action.
Highly Regioselective Ring Opening of Epoxides Using NaN3: A Short and Efficient Synthesis of (‐)‐Cytoxazone. (2004)

Abstract For Abstract see ChemInform Abstract in Full Text.
Ultra-Wideband Channel Sounder for Measurements at 70 GHz (2015)

Owing to the limitation in bandwidth of currently used frequency bands, future fifth generation (5G) mobile networks will need to operate at higher frequencies. However, one important step in the research activities for the next generation of mobile networks is the broadband fully polarimetric analysis of the multipath propagation in dynamic single and multiuser scenarios under time-variant shadowing environments in millimetre- wave (mm-wave) channels. This paper presents a channel sounding campaign at 70 GHz in an urban outdoor scenario focusing on broadband channel characteristic at mmwave. For the measurements a novel dual-polarized (DP) ultrawideband (UWB) multi-channel sounder (DP-UMCS) architecture, developed at the TU Ilmenau for propagation measurements in cellular networks, was used to study the directional and polarization properties of the channel in view of the future wireless communication systems.
Optical properties of raspberry-like SiO<inf>2</inf>@M<inf>n</inf> nanoclusters (2013)

Coupling of localized surface plasmon resonances results in singular effects at the void space between noble metal nanoparticles. Here, we present an approach that allows to produce raspberry-like nanoclusters in which metal nanoparticles are in close interaction. Two types of architectures based on isotropic or anisotropic metallic nanoparticles have been explored. Their production, in high yield and high amount, is based on colloidal chemistry methods. First optical characterization yields novel and intriguing plasmonic effects.
High Flow Through a Nasal Cannula and CPAP Effect in a Simulated Infant Model (2011)

Clinically important pressures were not generated by high flows with a standard nasal cannula. The differences in spontaneous V(T) across all flows were negligible.
ChemInform Abstract: CHEMISTRY AND SPECTROSCOPY OF F‐ELEMENT ORGANOMETALLICS. PART 1. THE LANTHANIDES (1979)

Abstract Review: Übersicht über allgemeine Eigenschaften der Lanthanidionen, ihrer Carbonyl‐ und Cyclopentadienylverbindungen sowie σ‐gebundenen Organometallverbindungen.
Are adjunctive markers useful in routine cervical cancer screening? Application of p16INK4a and HPV‐PCR on ThinPrep samples with histological follow‐up (2008)

The objectives of the study were to evaluate 1) the diagnostic sensitivity and specificity of p16(INK4a) as a marker for high-grade cervical lesions, 2) the results of a real-time polymerase chain reaction detecting high-risk human papillomavirus, and 3) the interobserver variability of the p16(INK4a) interpretation.A total of 232 ThinPrep samples were stained for p16(INK4a), and HPV-DNA PCR was performed on 107 specimens with inclusion of both benign and abnormal cytology. Histological follow-up information was collected. The diagnostic sensitivity of ASC+ with CIN2+ in histology as endpoint was 96% for p16(INK4a) and 100% for HR-HPV DNA PCR, and the diagnostic specificity was 41% and 27%, respectively. If p16(INK4a) had been used for triage of the ASC samples, then 18 patients (42%) could have been spared unnecessary follow-up procedures compared to six patients (21%) with the HR-HPV DNA test.
MP72-15 GENE EXPRESSION IN THE BLOOD OF INTERSTITIAL CYSTITIS PATIENTS AND CONTROLS DISTINGUISHES PATHWAYS ASSOCIATED WITH INTERSTITIAL CYSTITIS AND PREDICTS CLINICAL RESPONSE TO CYCLOSPORINE THERAPY (2016)

INTRODUCTION AND OBJECTIVES: Interstitial cystitis (IC) is a heterogeneous condition with urinary and systemic symptoms. Clinically relevant phenotyping has been a challenge, but some patients, especially those with Hunner's Ulcers, have evidence for immune activation. We hypothesize that gene expression signatures can be used as a biomarker to phenotype patients with IC and predict response to specific therapies.
Synthesis and application of a novel sunscreen-antioxidant (2006)

Background information on the inefficacy of sunscreens to provide free radical protection in skin, despite their usefulness in preventing sunburn/erythema, prompted us to synthesize a compound which would display in the same molecule both UV-absorbing and antioxidant capacities. For this purpose, the UVB absorber, 2-ethylhexyl-4-methoxycinnamate (OMC) was combined with the piperidine nitroxide TEMPOL, which has antioxidant properties. The spectral properties of the new nitroxide-based sunscreen (MC-NO) as well as its efficacy to prevent photo-oxidative damage to lipids induced by UVA, natural sunlight and 4-tert-butyl-4-methoxydibenzoylmethane (BMDBM), a photo-unstable sunscreen which generates free radicals upon UV radiation, was studied. The results obtained demonstrate that MC-NO: (a) absorbs in the UVB region even after UVA irradiation; (b) acts as free radical scavenger as demonstrated by EPR experiments; (c) strongly reduces both UVA-, sunlight- and BMDBM-induced lipid peroxidation in liposomes, measured as reduced TBARS levels; and (d) has comparable antioxidant activity to that of commonly used vitamin E and BHT in skin care formulations. These results suggest that the use of the novel sunscreen-antioxidant or of other nitroxide-based sunscreens in formulations aimed at reducing photoinduced skin damage may be envisaged.
Impact of FACTS devices on distance protection in transmission system (2014)

Due to the development in the field of Power Electonics many FACTS devices such as SVC, STATCOM, TCSC, UPSC are introduced in transmission lines. These devices are used to improve the system voltage profile, stability, Powerflow etc. Distance Relays are unique devices used to protect the transmission line from various faults. The reach of the relay is independent of the type of fault. Distance Relays are very sensitive to the apparent impedance seen by the relay and its zones. When a FACTS device say as TCSC is incorporated into the existing transmission line in order to improve the voltage profile, power flow, stability, etc it introduce problems in distance protection scheme in the measurement of the apparent impedance seen by the relay. Due to this significant change in the apparent impedance seen by the relay, it will lead to the mal operation of distance relay. This paper presents about the maloperation of distance protection of transmission line, when it is compensated by a series compensating device such as Thyrister Controlled Seies Capacitor(TCSC).
Studies on inactive kallikrein in rat urine (1983)

The present study was carried out to isolate an inactive kallikrein from rat urine by DEAE cellulose chromatography and to investigate some properties of this enzyme. Activity of kallikrein was measured by using Pro-Phe-Arg-4-methylcoumaryl-7-amide (Pro-Phe-Arg-MCA) as a substrate. An inactive kallikrein isolated by the DEAE cellulose column could be activated with trypsin, but not with high concentrations of NaCl, dithio-threitol and detergents such as SDS, Triton X-100 or deoxy-cholate. The molecular weight of this enzyme was estimated to be 44,000 by gel filtration on a Sephadex G-100 column, and the enzyme was converted to urinary active kallikrein (38,000) by trypsin treatment. The Km values for Pro-Phe-Arg-MCA hydrolysis by the trypsin-activated form of inactive kallikrein and active kallikrein were 0.12 and 0.11 mM, respectively. In addition, the activity of kallikrein, generated from the inactive kallikrein by trypsin treatment, was strongly inhibited by aprotinin, weakly by soybean trypsin inhibitor, but not at all by lima bean trypsin inhibitor or ovomucoid. The responses of the trypsin-activated form of inactive kallikrein to these protease inhibitors were similar to those of active kallikrein. These results indicate that an inactive kallikrein in the rat urine is converted to active kallikrein with an apparent change in molecular weight by trypsin treatment.
Transgenic α1A-adrenergic activation limits post-infarct ventricular remodeling and dysfunction and improves survival (2006)

Enhanced inotropy resulting from transgenic overexpression of alpha1A-AR is well maintained chronically after MI and limits echocardiography-determined LV remodeling, preserves function, and reduces acute heart failure death.
Halitosis as an indication for tonsillectomy in chronic hypertrophy tonsillitis (2019)

Main purpose: This paper aimed to confirm a relationship between chronic hypertrophic tonsillitis (CHT) and bad mouth odour. To this end, detailed identification of the microbial flora inhabiting affected tonsils was carried out. The results obtained might be helpful in specifying indications for tonsillectomy. Materials and method: From among 247 patients with clinically diagnosed CHT, 33 generally healthy individuals aged 18- 40 (10 male and 23 female) were selected. Patients in whom other causes could be the possible reason for their fetor ex ore (halitosis) were not included. Before and 2 to 3 months after tonsillectomy, organoleptic and halimeter testing was undertaken for each patient. A swab was collected from the interior of the enucleated tonsils in a sterile manner, and was inoculated onto surfaces enabling the culture of aerobic and anaerobic bacteria and fungi. A histopathological examination was subsequently performed. Results: Fetor ex ore was initially found in 95% of the patients with CHT. In 90% of cases with confirmed halitosis, after tonsillectomy a significant reduction in its intensity was observed. On average, the concentration of VSC in the patient decreased by approximately 75 ppb (62%), which was statistically significant (p < 0.0001). It was also shown that the concentration of VSC in carriers of anaerobic bacteria, compared to carriers of only aerobic bacteria, was significantly reduced (p < 0.05). The results obtained confirm the role of CHT in the pathogenesis of halitosis. Conclusions: Halitosis in patients with CHT requires a number of laboratory tests and specialist consultations to exclude other possible causes of fetor ex ore. A dental examination plays an important role in the differential diagnosis. Performing targeted microbiological testing to determine the patient’s carrier state for anaerobes should eventually be considered. When these conditions are met, halitosis can be considered an independent indication for tonsillectomy.
DENSITY OF STATES STUDY IN SPUTTERED a-Si : H : EFFECT OF IMPURITIES AND H RELATED DEFECTS (1981)

We observe two regimes in the variation of gap size (E04) and density of states (DOS) as a function of H-content (cH) in sputtered a-Si : H. In the first regime, an increase in cH from 5 to 17% is accompanied by an exponential functional decrease of the DOS near midgap, which varies also directly with E04 over a wide range of preparation conditions. In the second regime, additional incorporation of H beyond 17% fails to further decrease the DOS (with cH and E04), which shows a saturation with scatter. This behavior is interpreted in terms of H-induced and residual impurity related defects. Variation of the DOS in the lower half of the gap, responsible for hole trapping, is observed via the hole mobility-lifetime product, which exhibits a dramatic drop with impurity incorporation (P, O) and deteriorates for increasing cH in the second regime.
Development and experimental evaluation of a mathematical model to predict polymer-enhanced nanoparticle mobility in heterogeneous formations (2020)

A mathematical model is developed and evaluated for polymer-facilitated nanoparticle transport. Results demonstrate that the model can reproduce experimental observations of nanoparticle migration and attachment in a heterogeneous packed flow cell.
Finger Braille Teaching System for People who Communicate with Deafblind People (2007)

Finger Braille is one of tactual communication media of deafblind people. In finger Braille, index finger, middle finger and ring finger of both hands are likened to keys of a Braille typewriter. A sender dots Braille code on the fingers of a receiver like whether he/she does the type of the Braille typewriter. Then the receiver recognizes the Braille code. Deafblind people who are skilled in finger Braille can catch up with speech conversation and express various emotions. Because there are small non-disabled people who are skilled in finger Braille, deafblind people communicate only with interpreters. In this paper, we developed a finger Braille teaching system and designed a teaching interface which taught clauses explicitly. The teaching system recognized non-disabled people's speech and converted to Braille code. By parsing the Braille code, the teaching system retrieved clause information and segmented the Braille code into clauses. Then the dot pattern of the Braille code was displayed. By observing the dot pattern, non-disabled people dotted Finger Braille to deafblind people. An evaluation experiment between a blind person who was skilled in Finger Braille and two nondisabled people who were non-skilled in Finger Braille was carried out. The results showed that the fundamental functions (speech recognition, conversion to Braille code and clause segmentation) were practicable; the nondisabled senders could dot finger Braille accurately and communicate with the blind receiver directly. Therefore it was considered that the teaching system was effective.
Vehicle speed estimation by license plate detection and tracking (2014)

We describe a novel system for vehicle speed estimation from videos captured in urban roadways. Our system uses text detection to locate the license plates of passing vehicles, which are then used to select stable features for tracking. The tracked features are then filtered and rectified for perspective distortion. Vehicle speed is estimated by comparing the trajectory of the tracked features to known real world measures. In experiments performed on videos captured under real operation conditions, our system attained a precision of 0.87 and a recall of 0.92 for license plate detection. Vehicle speeds were estimated with an average error of 0.59 km/h, staying inside the +2/-3 km/h limit, determined by regulatory authorities in several countries, in over 75% of the cases.
Eupatilin Ameliorates Collagen Induced Arthritis (2015)

Eupatilin is the main active component of DA-9601, an extract from Artemisia. Recently, eupatilin was reported to have anti-inflammatory properties. We investigated the anti-arthritic effect of eupatilin in a murine arthritis model and human rheumatoid synoviocytes. DA-9601 was injected into collagen-induced arthritis (CIA) mice. Arthritis score was regularly evaluated. Mouse monocytes were differentiated into osteoclasts when eupatilin was added simultaneously. Osteoclasts were stained with tartrate-resistant acid phosphatase and then manually counted. Rheumatoid synoviocytes were stimulated with TNF-α and then treated with eupatilin, and the levels of IL-6 and IL-1β mRNA expression in synoviocytes were measured by RT-PCR. Intraperitoneal injection of DA-9601 reduced arthritis scores in CIA mice. TNF-α treatment of synoviocytes increased the expression of IL-6 and IL-1β mRNAs, which was inhibited by eupatilin. Eupatilin decreased the number of osteoclasts in a concentration dependent manner. These findings, showing that eupatilin and DA-9601 inhibited the expression of inflammatory cytokines and the differentiation of osteoclasts, suggest that eupatilin and DA-9601 is a candidate anti-inflammatory agent.