gebhart/patrepeval huggingface dataset:
[Pt(SCN)4]2–‐Based Coordination Polymers and Supramolecular Squares: Intermolecular Pt···H–C Interactions Probed by Luminescence Spectroscopy at Variable Pressure (2017)

The structures of four types of supramolecular systems containing [Pt(SCN) 4 ] 2– molecular units have been characterized. [Mn(bipy) 2 Pt(SCN) 4 ] 2 · 2MeOH ( 1 ) and [Zn(bipy) 2 Pt(SCN) 4 ] 2 · 2MeOH ( 2 ) show cis ‐thiocyanato ligands bridging the Pt II and Mn II or Zn II ions, leading to a molecular square motif. [Zn(bipy) 2 Pt(SCN) 4 ] 2 ( 3 ) presents chains where trans ‐thiocyanato ligands bridge the Zn II and Pt II ions. For 1 – 3 , free thiocyanato ligands are coordinated to the Pt II centers to complete the square‐planar coordination. [Pb(bipy) 2 Pt(SCN) 4 ] 2 ( 4 ) reveals a two‐dimensional sheet structure where all SCN – ligands bridge the Pb II and Pt II ions. [Pb(terpy)Pt(SCN) 4 ] 2 ( 5 ) is similar to 3 , with two bridging trans ‐SCN – ligands and two that are coordinated only to the Pt II centers. For all compounds, d–d luminescence is observed with band maxima at approximately 14600 cm –1 (690 nm). Spectra show characteristic shifts with pressure, indicative of either intramolecular or intermolecular effects, depending on the sign of the shift. The pressure‐dependent shifts for 1 – 5 show rich variations. A well‐documented shift to higher energy due to metal–ligand bond compression is observed for 5 and can be used as a basis for a comparison. Compounds 1 – 4 show a shift of E max to lower energy with pressures below 10 kbar. A change in sign for the shift of E max occurs at 20, 12, and 10 kbar for 1 , 2 , and 3 , respectively. For 4 , only a shift to lower energy is observed. Competing intra‐ and intermolecular effects lead to these variations.
Safety and efficacy of gamma‐secretase inhibitor nirogacestat (PF‐03084014) in desmoid tumor: Report of four pediatric/young adult cases (2020)

Systemic therapy for pediatric desmoid tumors has been challenged by a lack of high-quality clinical evidence and potential adverse effects. The gamma-secretase inhibitor nirogacestat has shown promising efficacy in adults. We report four cases of pediatric and young adult desmoid tumor patients (three with familial adenomatous polyposis [FAP] syndrome) who received nirogacestat on compassionate use. After a median of 13.5 months (range 6-18), three had durable benefit: a complete response (Case 1); a partial response (Case 2); stable disease (Case 3). The fourth had disease progression after a partial response. No patient experienced grade 3 or 4 adverse events.
A hybrid macrocyclic anion receptor exploiting the pyrrole-2,5-diacetamide unit (2016)

Macrocyclic compound built on pyrrole-2,5-diacetic bisamide was found to be an efficient receptor for H<sub>2</sub>PO<sub>4</sub><sup>−</sup>and PhCOO<sup>−</sup>.
Direct localization of a β-subunit domain on the three-dimensional structure of Escherichia coli RNA polymerase (2000)

To identify the location of a domain of the beta-subunit of Escherichia coli RNA polymerase (RNAP) on the three-dimensional structure, we developed a method to tag a nonessential surface of the multisubunit enzyme with a protein density easily detectable by electron microscopy and image processing. Four repeats of the IgG-binding domain of Staphylococcus aureus protein A were inserted at position 998 of the E. coli RNAP beta-subunit. The mutant RNAP supported E. coli growth and showed no apparent functional defects in vitro. The structure of the mutant RNAP was determined by cryoelectron microscopy and image processing of frozen-hydrated helical crystals. Comparison of the mutant RNAP structure with the previously determined wild-type RNAP structure by Fourier difference analysis at 20-A resolution directly revealed the location of the inserted protein domain, thereby locating the region around position 998 of the beta-subunit within the RNAP three-dimensional structure and refining a model for the subunit locations within the enzyme.
Initial progress and possible improvement of E-Cutter linear actuator development (2012)

Currently, palm oil has become the most consumed vegetable oil type. This is due to an awareness of the effect Trans Fat has on human health. Therefore, increasing productiveness is a crucial factor to ensure its continued availability as a product in the marketplace. One of the processes that should be improved to increase productivity is harvesting. The Malaysian Palm Oil Board (MPOB) has put a lot of effort into developing a mechanized harvesting tool called the Cantas™. This efficient tool has been shown to increase oil palm harvesting productivity by a factor of 3. However, Cantas™ is ineffective at harvesting oil palm fruit in trees taller than 8m. Therefore, a new tool called the E-Cutter was introduced. In this paper, the development progress of specifically the E-Cutter's linear actuator part was discussed. The previous type of linear actuator for the E-Cutter is also mentioned. Improvement in the planning and design target of the linear actuator is also addressed. The potential linear actuator structure and type is also identified.
58.2: Invited Paper : Novel High Efficiency Top Emission OLEDs for Display and Lighting Applications (2006)

Abstract We present results on low voltage and highly efficient OLED devices. The architecture based on doped transport layers is compatible with established manufacturing equipment, and shows long lifetime, good temperature stability, very low voltage drift, and very low heat dissipation. Main impacts are passive and active matrix displays with very low power consumption, use of a‐Si backplanes, and realization of ITO free structures, e.g. for lighting applications.
Effect of the ESOP Repurchase Obligation on Company Value (2006)

Abstract This article explores the impact of the repurchase liability that arises as a result of implementing an ESOP and suggests how appraisers can handle the repurchase liability when a repurchase liability study has not been conducted. The impact on a sponsoring company's value due solely to the repurchase obligation ranged from 12% to 35% in our study.
The Solubility of Carbon Dioxide in Water at Low Pressure (1991)

The system carbon dioxide-water is of great scientific and technological importance. Thus, it has been studied often. The literature for the solubility of carbon dioxide in water is vast and interdisciplinary. An exhaustive survey was conducted and approximately 100 experimental investigations were found that reported equilibrium data at pressures below 1 MPa. A model based on Henry’s law was used to correlate the low pressure data (those up to 1 MPa). The following correlation of the Henry’s constants (expressed on a mole fraction basis) was developed ln(H21/MPa)=−6.8346+1.2817×104/T−3.7668×106/T2 +2.997×108/T3 The correlation is valid for 273&amp;lt;T&amp;lt;433 K(0&amp;lt;t&amp;lt;160 °C) where T is in K. Any experimental data that deviated significantly from this model were duly noted.
Why make a diagnosis? (2007)

I read with interest Dr Evan Sadler's commentary regarding the papers by Goodeve and colleagues and James and colleagues in a recent issue of Blood .[1][1]

Since 2 large studies failed to associate a mutation with people followed in bleeding disorder clinics who have mild type 1 von Willebrand
Comparison of liver exposure in CT-guided high-dose rate (HDR) interstitial brachytherapy versus SBRT in hepatocellular carcinoma (2021)

HDR BT can be advantageous in respect of sparing of normal liver tissue as compared to SBRT, while providing excellent target conformity.
Preprocedural Statin Medication Reduces the Extent of Periprocedural Non–Q-Wave Myocardial Infarction (2002)

Preprocedural statin therapy is associated with a reduction in the incidence of larger-sized, stenting-related myocardial infarctions. Prospective, randomized trials are warranted to further assess this cardioprotective effect of statins in coronary intervention.
Kinome expression profiling and prognosis of basal breast cancers (2011)

Based on kinome expression, we identified a predictor that separated basal BCs into two subgroups of different prognosis. Tumors associated with higher activation of cytotoxic tumor-infiltrative lymphocytes harbored a better prognosis. Such classification should help tailor the treatment and develop new therapies based on immune response manipulation.
Chest Radiography in the ICU: Part 1, Evaluation of Airway, Enteric, and Pleural Tubes (2012)

The radiographic evaluation of the support and monitoring devices used in patients in the ICU is important because the potentially serious complications arising from their introduction and use are often not clinically apparent. Familiarity with normal and abnormal radiographic findings is critical for the detection of these complications.
Predicting postoperative knee flexion during gait of cerebral palsy children (2015)

International audience
Chronic Exposure to Arsenic and Markers of Cardiometabolic Risk: A Cross-Sectional Study in Chihuahua, Mexico (2020)

BackgroundExposure to arsenic (As) concentrations in drinking water > 150 μg/L has been associated with risk of diabetes and cardiovascular disease, but little is known about the effects of lower exposures.ObjectiveThis study aimed to examine whether moderate As exposure, or indicators of individual As metabolism at these levels of exposure, are associated with cardiometabolic risk.MethodsWe analyzed cross-sectional associations between arsenic exposure and multiple markers of cardiometabolic risk using drinking-water As measurements and urinary As species data obtained from 1,160 adults in Chihuahua, Mexico, who were recruited in 2008–2013. Fasting blood glucose and lipid levels, the results of an oral glucose tolerance test, and blood pressure were used to characterize cardiometabolic risk. Multivariable logistic, multinomial, and linear regression were used to assess associations between cardiometabolic outcomes and water As or the sum of inorganic and methylated As species in urine.ResultsAfter multivariable adjustment, concentrations in the second quartile of water As (25.5 to < 47.9 μg/L) and concentrations of total speciated urinary As (< 55.8 μg/L) below the median were significantly associated with elevated triglycerides, high total cholesterol, and diabetes. However, moderate water and urinary As levels were also positively associated with HDL cholesterol. Associations between arsenic exposure and both dysglycemia and triglyceridemia were higher among individuals with higher proportions of dimethylarsenic in urine.ConclusionsModerate exposure to As may increase cardiometabolic risk, particularly in individuals with high proportions of urinary dimethylarsenic. In this cohort, As exposure was associated with several markers of increased cardiometabolic risk (diabetes, triglyceridemia, and cholesterolemia), but exposure was also associated with higher rather than lower HDL cholesterol.CitationMendez MA, González-Horta C, Sánchez-Ramírez B, Ballinas-Casarrubias L, Hernández Cerón R, Viniegra Morales D, Baeza Terrazas FA, Ishida MC, Gutiérrez-Torres DS, Saunders RJ, Drobná Z, Fry RC, Buse JB, Loomis D, García-Vargas GG, Del Razo LM, Stýblo M. 2016. Chronic exposure to arsenic and markers of cardiometabolic risk: a cross-sectional study in Chihuahua, Mexico. Environ Health Perspect 124:104–111; http://dx.doi.org/10.1289/ehp.1408742
A general algorithm for distributed treatments of multiple brain metastases (2021)

The proposed approach models the clinical practice and provides an efficient solution for optimal selection of BM subsets for distributed SRS. Further evaluations are underway to establish this approach as a tool for improving clinical workflow and to facilitate systematic study on the benefits of distributed SRS treatments.
Automated liquid chromatographic compound class group-type separation of crude oils and bitumens using chemically bonded silica-NH2 (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAutomated liquid chromatographic compound class group-type separation of crude oils and bitumens using chemically bonded silica-NH2Patrick L. Grizzle and Donna M. SablotnyCite this: Anal. Chem. 1986, 58, 12, 2389–2396Publication Date (Print):October 1, 1986Publication History Published online1 May 2002Published inissue 1 October 1986https://doi.org/10.1021/ac00125a009RIGHTS & PERMISSIONSArticle Views231Altmetric-Citations68LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (972 KB) Get e-Alerts Get e-Alerts
Blood Compatibility of Titanium Oxides with Various Crystal Structure and Element Doping (2003)

Phosphorous doping of rutile TiO2 can increase its hemocompatibility, both concerning blood platelets and blood clotting cascade, but the biochemical mechanism has to be worked out.
Effets de l’aciclovir et du ganciclovir contre les herpèsvirus équins : suivi en temps réel par impédancemétrie. (2018)

National audience
Messung und Modellierung lokaler Phänomene in Polymer-Elektrolyt-Brennstoffzellen (2007)

Gegenstand der Arbeit ist die Entwicklung und Anwendung eines neuen in situ-Verfahrens zur Messung von Stromdichteverteilungen in Polymer-Elektrolyt-Brennstoffzellen, das auf einer Multilayer-Sensorplatine basiert. Mit Hilfe der Finite-Elemente-Methode wird die erreichbare Messgenauigkeit im Vergleich zu konventionellen Ansätzen quantifiziert und die Messunsicherheit aufgrund von Lateralströmen abgeschätzt. An Versuchszellen mit 100 cm² aktiver Fläche werden die Auswirkungen variabler Betriebsparameter auf die lokale elektrochemische Aktivität im stationären und dynamischen Betrieb untersucht. Lastzustände an der Anode werden in einem experimentell gestützten Modellansatz abgebildet und der charakteristische Wasserhaushalt mit Hilfe numerischer Strömungssimulationen analysiert.
Special winding to reduce space flux harmonics caused by fractional-slot (2012)

It is known that fractional-slot winding produces different harmonics from integral-slot winding. The authors studied space flux harmonics caused by fractional-slot winding and proposed a new winding method that reduces the low order space flux harmonic components (special winding method based on intersperse one coil winding), The advantage of this proposed winding method was confirmed using a model winding.
Effect of Cysteine 85 on Biochemical Properties and Biological Function of Human Surfactant Protein A Variants (2007)

Four "core" amino acid differences within the collagen-like domain distinguish the human surfactant protein A1 (SP-A1) variants from the SP-A2 variants. One of these, cysteine 85 that could form intermolecular disulfide bonds, is present in SP-A1 (Cys85) and absent in SP-A2 (Arg85). We hypothesized that residue 85 affects both the structure and function of SP-A1 and SP-A2 variants. To test this, wild-type (WT) variants, 6A2 of SP-A1 and 1A0 of SP-A2, and their mutants (6A2(C85R) and 1A0(R85C)) were generated and studied. We found the following: (1) Residue 85 affected the binding ability to mannose and the oligomerization pattern of SP-As. The 1A0(R85C) and 6A2(C85R) patterns were similar and/or resembled those of WT 6A2 and 1A0, respectively. (2) Both SP-A WT and mutants differentially induced rough LPS and Pseudomonas aeruginosa aggregation in the following order: 1A0 > 6A2 > 6A2(C85R) > 1A0(R85C) for Re-LPS aggregation and 1A0 > 6A2 = 6A2(C85R) = 1A0(R85C) for bacterial aggregation. (3) SP-A WT and mutants enhanced phagocytosis of P. aeruginosa by rat alveolar macrophages. Their phagocytic index order was 6A2(C85R) > 1A0 > 6A2 = 1A0(R85C). The activity of mutant 1A0(C85R) was significantly lower than WT 1A0 but similar to 6A2. Compared to WT 6A2, the 6A2(C85R) mutant exhibited a significantly higher activity. These results indicate that the SP-A variant/mutant with Arg85 exhibits a higher ability to enhance bacterial phagocytosis than that with Cys85. Residue 85 plays an important role in the structure and function of SP-A and is a major factor for the differences between SP-A1 and SP-A2 variants.
ChemInform Abstract: REDISTRIBUTION, CONDENSATION, AND REARRANGEMENT REACTIONS INVOLVING DICHLORO‐ AND DIMETHOXYMETHYLPHOSPHINES (1974)

Abstract Bei der Reaktion der Phosphine (I) und (II) (langsames Erwärmen des Reaktionsgemischs von ‐78°C auf Raumtemperatur) bildet sich durch Substituentenaustausch die Verbindung (III), daneben entstehen Kondensationsprodukte, und bei (II)‐Überschuß und längerer Reaktionsdauer erhält man das Oligomere (IV) (mit n948).
Magnetite biomineralization and geomagnetic sensitivity in higher animals: An update and recommendations for future study (1989)

Magnetite, the only known biogenic material with ferromagnetic properties, has been identified as a biochemical precipitate in three of the five kingdoms of living organisms, with a fossil record that now extends back nearly 2 billion years. In the magnetotactic bacteria, protoctists, and fish, single-domain crystals of magnetite are arranged in membrane-bound linear structures called magnetosomes, which function as biological bar magnets. Magnetosomes in all three of these groups bear an overall structural similarity to each other, which includes alignment of the individual crystallographic [111] directions parallel to the long axis. Although the magnetosomes represent only a small volume fraction in higher organisms, enough of these highly energetic structures are present to provide sensitivity to extremely small fluctuations and gradients in the background geomagnetic field. Previous experiments with elasmobranch fish are reexamined to test the hypothesis that gradients played a role in their successful geomagnetic conditioning, and a variety of four-turn coil designs are considered that could be used to test the various hypotheses proposed for them.
Un aigle à deux têtes : sublimer mais à quelle fin ? (1998)

Résumé Partant du fait que la sublimation représente en psychanalyse un concept inachevé et largement hypothétique mais qu'il apparaît, tout insaisissable soit-il, comme indispensable, la question d'une finalité sublimatoire de la cure sera examinée à la lumière des enseignements de la clinique, notamment celle des vicissitudes de l'économie narcissique chez des patients créatifs, et débouchera sur la reconnaissance d'une foncière ambiguïté du fonctionnement sublimatoire, véritable « aigle à deux têtes ». Il en découlera une prise de position prudente, récusant l'assignation d'une fina- lité sublimatoire au processus analytique et constatant qu'un bon mais également un mauvais usage peut être fait de la sublimation.
econdary Defects i es~luti~n of Fast-Neutr ma-Ray (1991)

The resolution characteristics of high-purity ger- manium gamma-ray detectors irradiated with fast neutrons are studied in detail. The influence of the neutron fluence on the energy resolution, as well as the annealing temperature of irradi- ated detectors are investigated. Similarities are observed between the annealing behavior of the defects created by fast neutron irradiation in high-purity germanium and the changes in the energy resolution of the detectors when they are annealed. The energy resolution of the detectors measured by the means of a resolution factor which takes into account tailing effects has been investigated. Its behavior has. been illustratively explained by the differences between the respective role of the stable defects at low temperature ( <lo0 K) and those formed by a thermal treatment up to room temperature.
Implementation and validation of a Raman lidar measurement of middle and upper tropospheric water vapor (1999)

Implementation of a Raman lidar measurement of middle and upper tropospheric water vapor is described for a system that uses a 532-nm exciting wavelength, fiber-optic signal transfer, and Q-branch selection. Particular attention is given to the minimization of systematic biases introduced by fluorescent reemission of energy associated with elastic backscatter returns. We compare lidar profiles with collocated radiosonde measurements by using the Vaisala H-Humicap capacitive captor. The variations in the water-vapor concentrations on vertical scales of the order of 1 km in the upper troposphere observed by the two instruments present significant differences. Independent characterization of random and systematic lidar measurement errors and radiosonde sensor response characteristics lead to the conclusion that these differences are due to radiosonde sensor response. These intercomparisons indicate that the lidar measurement can provide important information on water-vapor distributions in the radiatively important 8-11-km region.
Re-Establishment of Discrete-Time Parameter Adjustment Algorithms for Adaptive Systems (1988)

This paper presents a well generalized parameter adjustment algorithm for adaptive systems. It enables unified analysis of properties and relations of a variety of algorithms reported individually.
Global-ocean redox variation during the middle-late Permian through Early Triassic based on uranium isotope and Th/U trends of marine carbonates (2016)

Abstract Uranium isotopes (238U/235U) in carbonates, a proxy for global-ocean redox conditions owing to their redox sensitivity and long residence time in seawater, exhibit substantial variability in the Daxiakou section of south China from the upper-middle Permian through the mid-lower Triassic (∼9 m.y.). Middle and late Permian ocean redox conditions were similar to that of the modern ocean and were characterized by improving oxygenation in the ∼2 m.y. prior to the latest Permian mass extinction (LPME), countering earlier interpretations of sustained or gradually expanding anoxia during this interval. The LPME coincided with an abrupt negative shift of &amp;gt;0.5‰ in δ238U that signifies a rapid expansion of oceanic anoxia. Intensely anoxic conditions persisted for at least ∼700 k.y. (Griesbachian), lessening somewhat during the Dienerian. Th/U concentration ratios vary inversely with δ238U during the Early Triassic, with higher ratios reflecting reduced U concentrations in global seawater as a consequence of large-scale removal to anoxic facies. Modeling suggests that 70%–100% of marine U was removed to anoxic sinks during the Early Triassic, resulting in seawater U concentrations of &amp;lt;5% that of the modern ocean. Rapid intensification of anoxia concurrent with the LPME implies that ocean redox changes played an important role in the largest mass extinction event in Earth history.
The New Ternary Silicides Ln6Co1.67Si3 (Ln: Ce, Nd, Gd, Tb, Dy) Investigated by X‐Ray Diffraction and Magnetization Measurements. (2007)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.