gebhart/patrepeval huggingface dataset:
An Agent Based Architecture ForComponent-Based Software Development (1995)

Today's companies are facing major changes in their organizations due to the changing environment in which they operate. They have to decrease the costs, decrease time to market, and improve quality. These imperatives have led to changes in the placement and role of IS department in the organization (Fried, 1995). Together with the recent advances in communication technology and powerful workstations, end-users have become more involved with the application development. Besides, the business processes change so fast that the traditional SDLC is too slow to keep up with these fluctuating requirements in the application domain. The need for rapid application development to respond to users' changing needs, among the other mentioned trends, encourages the use of reusable software components. In (ATP, 1995), it is stated that at the level of vertical-market products, software design costs are generally $1 million to $10 million with near zero cost of reproducing additional units, and the typical production quantity is one. Reusable software components help organizations recover costs, improve quality through specialization, and develop rapidly from existing components.
Preparation of a new soft capsule for cosmetics (2000)

A novel microcapsule for cosmetics was studied. The microcapsule was prepared by using an O/W/O emulsification technique and showed high thermostable properties (> 70°C). Agar was employed to gel the water phase of the emulsion. The size of the microcapsules was controlled by the process temperature and the stirring speed: the higher the temperature or the stirring speed, the smaller the diameter of the microcapsule produced. The strength of the agar gel phase was investigated, and the effect of the ratio of the internal oil to the gel (water) phase was observed. Young's modulus decreased with increase of the internal oil ratio. For cosmetic applications of the microcapsules, the all trans-retinol palmitate or ethyl linoleate used as a model ingredient was stabilized by microencapsulation. The remaining percentages of all trans-retinol palmitate and ethyl linoleate in the microcapsule after the four-week experiments at 50°C were 87% and 95%, respectively. On the other hand, those in oil solution were 72% and 91%, respectively. This microcapsule shows suitable properties for not only cosmetic use, but also for applications in foods and other products.
Antibiotic Therapy for Acute Otitis, Rhinosinusitis, and Pharyngotonsillitis (2009)

Classification of otitis media and bacterial rhinosinusitis into acute, recurrent and chronic impacts treatment decisions. Other variables of importance include the child’s age, symptom severity, prior treatment history and daycare attendance.


The etiology of both acute otitis media (AOM) and acute bacterial rhinosinusitis (ABRS) are similar, with the predominant pathogens being Haemophilus influenzae, Streptococcus pneumoniae, and Moraxella catarrhalis.


Symptomatic and adjunctive therapies other than pain relievers are of limited value.


Guidelines have been promulgated for antibiotic selection for both AOM and ABRS. Amoxicillin is recommended as first line. Amoxicillin/clavulanate, cefuroxime, cefpodoxime, and cefdinir are preferred as oral second-line agents. Duration of antibiotic therapy may be shortened to 5 days for many cases.


Group A beta hemolytic streptococci (GABHS) are the major pathogens of the tonsillopharynx requiring antibiotic treatment.


GABHS are sensitive in vitro to penicillins, macrolides, and cephalosporins. To eradicate GABHS, antibiotic concentrations in the throat must exceed minimum defined concentrations for time spans that vary with the drug.


Penicillin is the treatment of choice endorsed by all guidelines. Cephalosporins produce better bacteriologic and clinical cure rates than penicillin; this superiority in outcomes has been increasing for over two decades.
High resolution MCD and phosphorescence excitation spectroscopy of Mn2+in KMgF3and KZnF3 (1974)

A combination of high resolution MCD and phosphorescence excitation techniques has been used to determine, for the first time, the optical spectra of single Mn2+ ions in the cubic perovskite hosts KMgF3 and KZnF3. Particular attention has been paid to transition mechanisms, spin-orbit effects and vibronic structure, and the experimental results have been compared with theoretical crystal field calculations based on the complete d 5 configuration. All of the states arising from the 4 G, 4 P and 4 D terms have been observed and a dynamic Jahn-Teller effect has been observed in the 4 T 1g a state. Both magnetic dipole and electric dipole (vibrationally induced) absorption processes occur and the former is most important for transitions to the 4 T 1g a , 4 A 1g , 4 T 1g b states. Calculated and observed magnetic dipole intensities are in good agreement. A complete analysis of the zero phonon (magnetic dipole) lines and vibronic (magnetic and electric dipole) side-bands associated with transitions to 4 A 1g and 4 E g a states has been made.
FourierSAT: A Fourier Expansion-Based Algebraic Framework for Solving Hybrid Boolean Constraints (2019)

The Boolean SATisfiability problem (SAT) is of central importance in computer science. Although SAT is known to be NP-complete, progress on the engineering side, especially that of Conflict-Driven Clause Learning (CDCL) and Local Search SAT solvers, has been remarkable. Yet, while SAT solvers aimed at solving industrial-scale benchmarks in Conjunctive Normal Form (CNF) have become quite mature, SAT solvers that are effective on other types of constraints, e.g., cardinality constraints and XORs, are less well studied; a general approach to handling non-CNF constraints is still lacking. In addition, previous work indicated that for specific classes of benchmarks, the running time of extant SAT solvers depends heavily on properties of the formula and details of encoding, instead of the scale of the benchmarks, which adds uncertainty to expectations of running time. To address the issues above, we design FourierSAT, an incomplete SAT solver based on Fourier analysis of Boolean functions, a technique to represent Boolean functions by multilinear polynomials. By such a reduction to continuous optimization, we propose an algebraic framework for solving systems consisting of different types of constraints. The idea is to leverage gradient information to guide the search process in the direction of local improvements. Empirical results demonstrate that FourierSAT is more robust than other solvers on certain classes of benchmarks.
Xenon in the gastric fundus: potential pitfall in ventilation scan interpretation (1979)

Xenon in the gastric fundus: potential pitfall in ventilation scan interpretationWJ Marx, JV Courtney, H MacMahon and K Rezai-ZadehAudio Available | Share
Enhanced low field magnetoresistance in nanocrystalline La0.7Sr0.3MnO3 synthesized on MgO nanowires (2010)

We report on the structure and transport properties of nanocrystalline manganite La0.7Sr0.3MnO3 (LSMO) synthesized on nanowires-engineered MgO substrates by pulsed laser deposition, which is compared with reference samples deposited directly on flat MgO substrates. Such LSMO/MgO nanocomposites show enhanced low field magnetoresistance, especially at low temperature, due to the dominant spin-polarized intergrain tunneling. This work suggests that growing on nanoengineered substrates is a viable route to achieve nanostructured materials with desired crystalline structure and physical properties.
Prosodic generation research (1976)

Recently, research on sentence prosody has been carried out using the computerized audio synthesis and analysis facilities at IMSSS. The aim of this research has been to synthesize sentences with an acceptable-sounding prosodic contour using only the phonetic information contained in the individually recorded words contained in those sentences together with certain syntactic/semantic facts that can be derived from the structure of the sentence or read out of a lexicon. We demonstrate the importance of surface syntax to prosodic assignment and suggest that a prosodic synthesis system can be constructed which will be based largely on the surface syntax.
Sickle Cell Disease: Advances in Treatment (2018)

These examples demonstrate how the current knowledge of sickle cell disease pathophysiology and treatment approaches intersect. Although interest in sickle cell research has blossomed, many more clinical trials need to be initiated and subjected to more strenuous examination and analysis than have been used in the past.
Digital implementation of a new type of hybrid filter with simplified control strategy (1999)

A new type of hybrid active filter to compensate harmonics of a nonlinear load is presented in this paper. The proposed topology of hybrid filter combines a shunt passive filter (PF) and a shunt active filter (AF). A series inductor between both the filters is introduced to create a harmonic voltage source at the input of nonlinear load. A diode bridge rectifier with R-C load is considered as a nonlinear load. An indirect current controlled voltage source inverter (ICC-VSI) is considered as an AF. A simple control algorithm based on proportional plus integral control of a self-supporting DC bus voltage of the shunt AF is implemented on a TMS320C31 DSP. The passive filter is tuned to compensate 5/sup th/ and 7/sup th/ harmonics, while the AF compensates the rest of harmonics of the load current. A laboratory prototype model of the proposed hybrid filter is developed and its performance is examined. Experimental results are given and discussed.
Angle-of-arrival reception for optical wireless location technology (2015)

An optical wireless location (OWL) system is introduced for indoor positioning. The OWL system makes use of a mobile photoreceiver that facilitates triangulation by measuring angle-of-arrival (AOA) bearings from LEDs in an optical beacon grid. The photoreceiver has three photodiodes (PDs), arranged in a corner-cube, to facilitate differential photocurrent sensing of the incident light AOA, by way of azimuthal ϕ and polar θ angles. The AOA error for indoor positioning is characterized empirically. Optical AOA positioning is shown to have a fundamental advantage over known optical received signal strength (RSS) positioning, as AOA estimation is insensitive to power and alignment imbalances of the optical beacon grid. The OWL system is built, and a performance comparison is carried out between optical AOA and RSS positioning. It is shown that optical AOA positioning can achieve a mean 3-D positioning error of only 5 cm. Experimental design and future prospects of optical AOA positioning are discussed.
Psychotropic Drugs Associated With Corrected QT Interval Prolongation (2009)

In this population-based prospective cohort study, we confirmed the importance of antidepressants and antipsychotics as potential contributors to QTc prolongation. Especially, starting tricyclic antidepressant drugs (as a class) is associated with a significant intraindividual increase in the QTc interval in comparison to the change in nonusers. The tricyclic antidepressants seem to prolong the QTc interval as a class effect.
Liquid target pulsed laser deposition (1995)

A novel pulsed laser deposition (PLD) technique using a liquid target has been developed. The technique overcomes the problem of solid target deterioration under high power laser irradiation and prevents splashing of large particulates on the substrate. Choosing an organic liquid containing carbon and hydrogen as a testing target, we have obtained high quality hydrogenated carbon films with a large amount of tetrahedral (diamond-like) sp3 bonding.
Characterization of deformation-induced martensite by cryogenic turning using eddy current testing (2022)

The formation of deformation-induced martensite upon cryogenic turning results in a substantial hardening of the surface. In this study, eddy current testing was used to gain a deeper insight in the microstructural evolution. Electromagnetic simulations were used to separate the various contributions to the measurement signal. The overall martensite content is strongly correlated with the measurement signal. However, the actual martensite structure also affects the signals. Thus, eddy current testing not only has the potential to control the evolution of the martensite content during the cutting process but also can provide information about the finer details of the martensitic microstructure.
Porting a core CGI workflow system onto a WAS platform while being used and extended to support the enterprise (2000)

This paper describes our experiences with evolving a system infrastructure while continuing to support new functionality. In it we explore the architecture, technology decisions made, and difficulties encountered in porting a core business application while it is being used and extended to support the enterprise.
Phase I Study of Stealth Liposomal Doxorubicin in Combination With Gemcitabine in the Treatment of Patients With Metastatic Breast Cancer (2001)

The combination of liposomal doxorubicin and gemcitabine is an active and well tolerated regimen when administered on a 21-day schedule. Myelosuppression limited further dose escalation, however, it did not increase the incidence of neutropenic fever. Significant antitumor activity seen in heavily and minimally pretreated patients warrants further evaluation of this combination.
Peptide Hydrogelation and Cell Encapsulation for 3D Culture of MCF-7 Breast Cancer Cells (2013)

Three-dimensional (3D) cell culture plays an invaluable role in tumor biology by providing in vivo like microenviroment and responses to therapeutic agents. Among many established 3D scaffolds, hydrogels demonstrate a distinct property as matrics for 3D cell culture. Most of the existing pre-gel solutions are limited under physiological conditions such as undesirable pH or temperature. Here, we report a peptide hydrogel that shows superior physiological properties as an in vitro matrix for 3D cell culture. The 3D matrix can be accomplished by mixing a self-assembling peptide directly with a cell culture medium without any pH or temperature adjustment. Results of dynamic rheological studies showed that this hydrogel can be delivered multiple times via pipetting without permanently destroying the hydrogel architecture, indicating the deformability and remodeling ability of the hydrogel. Human epithelial cancer cells, MCF-7, are encapsulated homogeneously in the hydrogel matrix during hydrogelation. Compared with two-dimensional (2D) monolayer culture, cells residing in the hydrogel matrix grow as tumor-like clusters in 3D formation. Relevant parameters related to cell morphology, survival, proliferation, and apoptosis were analyzed using MCF-7 cells in 3D hydrogels. Interestingly, treatment of cisplatin, an anti-cancer drug, can cause a significant decrease of cell viability of MCF-7 clusters in hydrogels. The responses to cisplatin were dose- and time-dependent, indicating the potential usage of hydrogels for drug testing. Results of confocal microscopy and Western blotting showed that cells isolated from hydrogels are suitable for downstream proteomic analysis. The results provided evidence that this peptide hydrogel is a promising 3D cell culture material for drug testing.
Analog Signal Transmission in a High-Contrast-Gratings-Based Hollow-Core-Waveguide (2012)

In this paper, the performance of an on-chip hollow-core-waveguide (HW) using high-contrast gratings (HCG) for analog signal transmission is analyzed numerically. Simulation results indicate that after propagating 100 m in a HCG-HW with optimally designed parameters, there is very little degradation of either third-order intermodulation distortion spur-free dynamic range (IM3 SFDR) or third-order harmonic distortion (THD) SFDR. Due to the chromatic dispersion of the HCG-HW, the highest second-order harmonic distortion (SHD) SFDR is limited to 107.3 dB · Hz <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1 / 2</sup> . In addition, >; 100 dB · Hz <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2/3</sup> IM3 SFDR can be achieved over a radio frequency (RF) range of 80 GHz and an optical wavelength bandwidth of 50 nm after propagation 100 m through a HCG-HW. The parameter dependence of the waveguide performance is also investigated. With a ± 20 nm variation on all parameters, the propagation length in an HCG-HW is limited to ~ 6 m in order to maintain an IM3 SFDR of >; 100 dB · Hz <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2 / 3</sup> .
Isolation and Complete NMR and X-ray Crystallographic Characterization of an Unusual Pentadienyllutetium Complex, (.eta.5-Me2C5H5)Lu(.eta.5:.eta.3-MeC5H5CH2CH2CHMeC3H3Me) (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIsolation and Complete NMR and X-ray Crystallographic Characterization of an Unusual Pentadienyllutetium Complex, (.eta.5-Me2C5H5)Lu(.eta.5:.eta.3-MeC5H5CH2CH2CHMeC3H3Me)Matthew B. Zielinski, Donald K. Drummond, Pradeep S. Iyer, John T. Leman, and William J. EvansCite this: Organometallics 1995, 14, 8, 3724–3731Publication Date (Print):August 1, 1995Publication History Published online1 May 2002Published inissue 1 August 1995https://pubs.acs.org/doi/10.1021/om00008a020https://doi.org/10.1021/om00008a020research-articleACS PublicationsRequest reuse permissionsArticle Views81Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information Get e-Alerts
Abstract 1088: Prevention of Connexin 43 (Cx43) Dephosphorylation is Associated with Reduced Ventricular Tachycardia in Cardiac-Specific Angiotensin Converting Enzyme (ACE) Overexpression Mice (2007)

Introduction: Connexin 43 (Cx43) is a major component of the ventricular gap junctional complex, which provides a low resistance pathway for electrical conduction between myocytes. Reduction of Cx43 amount of phosphorylation has been implicated in the pathogenesis of ventricular tachycardia (VT) and fibrillation. Cardiac-specific angiotensin converting enzyme overexpression mice (ACE 8/8) have slow conduction, show conduction blocks, are prone to VT and sudden death, and show profound reductions in Cx43 levels and phosphorylation. Therefore, we hypothesized that reversal of Cx43 changes, by preventing the renin-angiotensin system (RAS) activation, would reduce the arrhythmic risk in these animals. Methods: Prevention of RAS activation was accomplished by one of three methods: ACE 8/8 receiving an ACE inhibitor (captopril), ACE 8/8 mice treated with a specific angiotensin receptor type-1 blocker (losartan), and ACE 8/8 mice crossed with homozygote angiotensinogen null mice. Pooled results were compared to untreated ACE 8/8 littermates. Surface electrocardiography and invasive electrophysiological study with programmed ventricular stimulation were performed on ten-week old mice, and the hearts were extracted for immunoblotting. Results: VT was induced in 10 out of 12 untreated ACE 8/8 mice, but only in 3 out of 11 treated mice (p&lt;0.02). Total Cx43 was not changed significantly in treated animals as compared to controls, but the ratio (P/NP) of phosphorylated Cx43 (bands P1 and P2 in immunoblot) to non-phosphorylated Cx43 (band P0) showed a trend toward increase in the treatment group (0.78±0.18 vs. 1.25±0.19; P=0.09). Dividing the mice into two groups, high-risk (inducible and/or spontaneous VT) versus low-risk (no VT), we observed a significant difference in P/NP ratio (0.75±0.12 in high-risk mice vs. 1.78±0.32 in low-risk, p&lt;0.01). Discussion: Unexpectedly, disruption of RAS signaling did not increase total Cx43 levels in ACE 8/8 mice. On the other hand, the treatments increased phospho-Cx43, suggesting that RAS controls Cx43 phosphorylation but not total amount. Even in the presence of significantly depressed levels of Cx43, small changes in Cx43 phosphorylation were associated with a significant reduction in VT inducibility.
Total Synthesis of the Sphingolipid Biosynthesis Inhibitor Fumonisin B1 (2009)

The first total synthesis of the sphingolipid biosynthesis inhibitor fumonisin B(1) has been achieved. This convergent synthesis utilizes oxonia Cope rearrangements to prepare two key homoallylic alcohols, which are then functionalized to the primary components A and B for cross-coupling. Other highlights of our approach include a new and efficient synthesis of the diprotected tricarballylic acid C and a global deprotection strategy as the final step.
Nonlinear constructive interference in electrical lattices (2008)

We analyze the constructive interference of input signals in nonlinear, discrete, two-dimensional media. The media consist of inductor-capacitor lattices with saturating, voltage-dependent capacitors. We find that nonlinearity significantly boosts the ability of such media to generate large-amplitude output signals from small-amplitude inputs. To understand this boosting, we develop a general perturbative method suitable for finding the steady-state solution of a damped NxN nonlinear lattice that is driven at a single frequency. We verify our theory using extensive numerical simulations.
The Golay code and a code on the Klein quartic curve (2002)

The (24,12,8) Golay code over GF(2) is constructed as the subfield-subcode of a three symbol extended (21,16,4) code constructed on the Klein quartic over GF(8) in a nontraditional way.
Tradeoff between Area Spectral Efficiency and End-to-End Throughput in Rate-Adaptive Multihop Radio Networks (2005)

We investigate the impact of symbol rate control, modulation level control, and the number of hops on the area spectral efficiency of interference-limited multihop radio networks. By controlling symbol rate and modulation level, data rate can be adapted according to received power. In addition, varying the number of hops can control received power. First., we evaluate the achievable end-to-end throughput of multihop transmission assuming symbol rate and modulation level control. Numerical results reveal that by controlling symbol rate or using multihop transmission, the end-to-end communication range can be extended at the cost of end-to-end throughput, and this may result in lower area spectral efficiency. Next, an expression for the area spectral efficiency of multihop radio networks is derived as a function of the number of hops and the end-to-end throughput. Numerical results also reveal that the resulting area spectral efficiency depends on the specific circumstances, which, however, can be increased only by using multihop transmission.
Quantification of Momilactones A and B in Rice Straw (2002)

Momilactones A and B, the major phytotoxins and phytoalexins in rice plants, were quantified by a HPLC-APCI-MS-MS (APCI-MS-MS) system under multiple reaction monitoring conditions. Since MA and MB were found to be easily extracted with water, these phytotoxic compounds may affect germination and growth of other plant species when the rice straws were left in the fields.