gebhart/patrepeval huggingface dataset:
Bipolar fractional radiofrequency treatment induces neoelastogenesis and neocollagenesis (2009)

Our study revealed a vigorous wound healing response is initiated post-treatment, with progressive increase in inflammatory cell infiltration from day 2 through 10 weeks. An active dermal remodeling process driven by the collagen chaperone HSP47 led to complete replacement of RFTZs with new collagen by 10 weeks post-treatment. Furthermore, using both immunohistochemical and PCR studies, we successfully demonstrated for the first time evidence of profound neoelastogenesis following RF treatment of human skin. The combination of neoelastogenesis and neocollagenesis induced by treatment with the FRF system may provide a reliable treatment option for skin laxity and/or rhytids.
A Versatile Computer Interface for Experiment Control and Data Acquisition. (1984)

ABSTRACT A computer interface for experiment control has been constructed. The interface uses serial communication with a controlling computer which makes it suitable for use with almost any computer. The interface has been used for automated complexometric investigations, but can be applied in many different experiment control tasks.
3D imaging of amplitude objects embedded in phase objects using transport of intensity (2015)

The amplitude and phase of the complex optical field in the Helmholtz equation obey a pair of coupled equations, arising from equating the real and imaginary parts. The imaginary part yields the transport of intensity equation (TIE), which can be used to derive the phase distribution at the observation plane. If a phase object is approximately imaged on the recording plane(s), TIE yields the phase without the need for phase unwrapping. In our experiment, the 3D image of a phase object and an amplitude object embedded in a phase object is recovered. The phase object is created by heating a liquid, comprising a solution of red dye in alcohol, using a focused 514 nm laser beam to the point where self-phase modulation of the beam is observed. The optical intensities are recorded at various planes during propagation of a low power 633 nm laser beam through the liquid. In the process of applying TIE to derive the phase at the observation plane, the real part of the complex equation is also examined as a cross-check of our calculations. For pure phase objects, it is shown that the real part of the complex equation is best satisfied around the image plane. Alternatively, it is proposed that this information can be used to determine the optimum image plane.
Exhibition method of hierarchical structure of Web communities using community density for Web video retrieval (2014)

In this paper, we present an exhibition method of hierarchical structure of Web communities using community density for Web video retrieval. In the proposed method, Web communities that are Web video sets with similar topics is hierarchically extracted by using hyperlinks between Web videos and their video features, and density of each Web community is estimated. Then we exhibit the hierarchical structure of Web communities according to the obtained density to users. Since users can grasp detail degree of topics contained in each Web community, the desired Web community can be easily selected for Web video retrieval.
Automatic measurement of crops canopy height based on monocular vision (2011)

Computer vision technology has been increasingly used for automatically observing crop growth state, but as one of the
key parameters in the field of agro-meteorological observation, crop canopy height is still measured manually in the
actual observation process up to now. In order to automatically measure the height based on the forward-and-downward-looking
image in the existing monocular vision observation system, a novel method is proposed, that is, to measure the
canopy height indirectly by the solving algorithm for the actual height of the vertical objects (SAAH) with the help of the
intelligent sensor device. The experiment results verified the feasibility and validity of our method, and that the method
could meet the actual observation demand.
Voltage-operated calcium channels in fresh and cultured rat retinal pigment epithelial cells. (1993)

Voltage-operated calcium channels of the L-type are the main calcium channels present in rat RPE cells. Cultured cells retained the identical channels. The dystrophic RCS strains (studied until 17 days postnatal) also exhibited these channels.
The Influence of Satellite Observation Angle on Tropical Cyclone Intensity Estimation using the Deviation Angle Variance Technique (2019)

Based on 12 years (2004-2015) of GOES-East satellite infrared (IR) imagery over the North Atlantic basin, the diurnal cycle of the tropical cyclone (TC) Deviation Angle Variation (DAV) value is analysed, and a backward 24-hr time average DAV is selected to filter the noise in the DAV-TC intensity estimation. The effect of satellite observation angle on the DAV-TC intensity estimation is analysed in theory, in a case study, and in the longer-term statistics. Based on these results, an improvement to the DAV-TC intensity estimation is presented and evaluated in this study. The results show that, after taking the observation angle into account, the new DAV-TC intensity estimation is shown to produce smaller errors and higher correlations than the previous versions, especially for major hurricanes.
205 POLY(ADP-RIBOSE) POLYMERASE-14 INTERACTS WITH TRISTETRAPROLIN TO SELECTIVELY REGULATE TISSUE FACTOR MRNA STABILITY: A NOVEL ROLE FOR ADP-RIBOSYLATION IN REGULATING MRNA TURNOVER AND THROMBOSIS (2013)

<h3>Background</h3> Targeting post-transcriptional pathways is now emerging as a promising therapeutic strategy in a wide spectrum of diseases. Monocyte-derived tissue factor (TF) plays critical roles in atherothrombosis, but little is known about its post-transcriptional regulation. Tristetraprolin (TTP) is the most widely studied mRNA-binding protein that binds to the 3’UTR of target mRNAs and promotes degradation. Its function is negatively regulated by p38 MAPK. Poly(ADP-ribose)-polymerase-14 (PARP-14) belongs to a family of ∼17 proteins with a PARP domain that generates negatively charged poly(ADP-ribose) adducts on intracellular proteins a post-translational modification implicated in diverse cellular functions. <h3>Objective</h3> We sought to determine the roles for TTP and PARP-14 in regulating TF expression, and the potential role of ADP ribosylation in regulating TF mRNA turnover. <h3>Methods/Results</h3> Compared to WT macrophages TF mRNA and protein expression were increased in TTP<sup>−/−</sup> and PARP-14<sup>−/−</sup> macrophages (both p&lt;0.05). This was paralleled by an increase in TF mRNA stability in TTP<sup>−/−</sup>and PARP-14<sup>−/−</sup> macrophages (both p&lt;0.001). TF mRNA, activity and protein were increased <i>in vivo</i> (heart, lung, kidney, aorta and circulating leukocytes) in PARP-14<sup>−/−</sup> vs WT mice (p&lt;0.05). Intravital microscopy demonstrated a 66% reduction in median arteriolar occlusion time in LPS-stimulated PARP-14<sup>−/−</sup> vs WT mice following ferric-chloride injury (p=0.008). RNP immunoprecipitation and RNA biotin pulldown assays demonstrated an interdependency for PARP-14 and TTP to form a ternary complex with TF mRNA. p38 inhibition reduced TF mRNA stability in WT but not in TTP<sup>−/−</sup> or PARP-14<sup>−/−</sup> macrophages. Inhibition of PARP activity reduced TF mRNA stability in WT macrophages (p=0.018), but not in PARP-14<sup>−/−</sup> macrophages. Interestingly, PARP-14 conferred selectivity for TTP to degrade TF mRNA, as PARP-14 deficiency had no effect on TNFα, an established target of TTP, both <i>in vitro</i> and <i>in vivo</i>. Accordingly, PARP inhibition had no effect on TNFα mRNA decay. <h3>Conclusions</h3> These data define novel roles for TTP and PARP-14 in the selective regulation of TF mRNA turnover. PARP-14 functions as an accessory RNA-binding protein which is required for TTP to bind and degrade TF mRNA. These data indicate that both p38-mediated phosphorylation and PARP-14-mediated ADP-ribosylation are required to inhibit TTP-mediated TF mRNA decay. These data also show for the first time how the actions of TTP may be selectively regulated. Thus selective destabilization of TF mRNA via pharmacological inhibition of PARP-14 may offer a novel therapeutic strategy in atherosclerosis and cardiovascular disease where thrombosis is linked to inflammation-induced TF expression.
Identification of Target Genes Involved in the Antiproliferative Effect of Glucocorticoids Reveals a Role for Nuclear Factor-κB Repression (2004)

Abstract Glucocorticoid hormones (GCs) exert an antiproliferative effect on most cells. However, the molecular mechanism is still largely unclear. We investigated the antiproliferative mechanism by GCs in human embryonic kidney 293 cells with stably introduced glucocorticoid receptor (GR) mutants that discriminate between cross-talk with nuclear factor-κB (NF-κB) and activator protein-1 signaling, transactivation and transrepression, and antiproliferative vs. non-antiproliferative responses. Using the GR mutants, we here demonstrate a correlation between repression of NF-κB signaling and antiproliferative response. Gene expression profiling of endogenous genes in cells containing mutant GRs identified a limited number of genes that correlated with the antiproliferative response. This included a GC-mediated up-regulation of the NF-κB-inhibitory protein IκBα, in line with repression of NF-κB signaling being important in the GC-mediated antiproliferative response. Interestingly, the GC-stimulated expression of IκBα was a direct effect despite the inability of the GR mutant to transactivate through a GC-responsive element. Selective expression of IκBα in human embryonic kidney 293 cells resulted in a decreased percentage of cells in the S/G2/M phase and impaired cell proliferation. These results demonstrate that GC-mediated inhibition of NF-κB is an important mechanism in the antiproliferative response to GCs.
Voxento 3.0: A Prototype Voice-Controlled Interactive Search Engine for Lifelog (2022)

Voxento is an interactive voice-based retrieval system for lifelogs which has been redeveloped and optimised to participate in the fifth Lifelog Search Challenge LSC'22, at ACM ICMR'22. Based on the previous experience in the LSC competition and ranked in the top 4 in the last LSC'21 competition among 17 participants, we present a revised version of Voxento to address the critical points to improve the efficiency of retrieval tasks in lifelog datasets. Basically, Voxento provides a spoken interface to the lifelog data, which facilitates an expert and novice user to interact with a personal lifelog using a range of vocal commands and interactions. Briefly, we made some important improvements to support both the retrieval of content and system interaction. This latest version has been enhanced with the addition of a text-based search feature, new filters based on new metadata provided in lifelog data, rich visual information and features and enhanced speech query. Also, the data preparation tasks comprised a new function to reduce the number of non-relevant images and the latest CLIP model version used to derive features from images. The long term development of Voxento includes a lifelog retrieval that supports speech and conversation interaction with less physical actions required by users such as using a mouse. The system presented here uses a desktop computer in order to participate in the LSC'22 competition with the option to use voice interaction or standard text-based retrieval.
Size and Shape Control of Monodisperse FePt Nanoparticles (2007)

Morphological control of FePt nanoparticles has been systematically studied. By varying synthetic parameters including precursors, solvents, amount of surfactants, and heating rate of the solution, the particle size from 2 to 9 nm can be tuned with 1 nm accuracy. While most particles are spherical in shape, cubic particles can be obtained when particles are greater than 7 nm. Rod-shape nanoparticles have also been obtained. The as-synthesized nanoparticles are found to be superparamagnetic at room temperature and their blocking temperature is size dependent that increases with particle size. After annealing in a reducing atmosphere, the nanoparticles form hard magnetic films with ordered fct structure and high coercivity up to 2.7 T.
Optical spectroscopy of platinum and palladium containing poly-ynes (1994)

We present a comparative study of two isostructural platinum and palladium poly-ynes, poly[trans(bis(tributylphosphine))M(1,4) phenylenediethynylene], where M represents either platinum or palladium. Optical excitations are associated with the π-molecular orbitals, and with strong spin–orbit coupling provided by the transition metal, both singlet and triplet excitations can be measured. The platinum and palladium polymers show similar low-temperature photoluminescence and photoinduced absorption spectra, with a blue-shift for the palladium polymer of around 5% for electronic transitions with respect to the platinum polymer. For Pt (Pd) we see strong singlet absorption peaks at 3.26 eV (3.49 eV), and weaker triplet absorption peaks at 2.43 eV (≊2.5 eV) at room temperature. Strong photoluminescence from triplet to ground state peaks at 2.38 eV (2.5 eV), and weak photoluminescence from the excited singlet peaks at 3.06 eV (3.2 eV) at low temperatures. Photoinduced absorption that peaks at 1.49 eV (1.72 eV) is due to transitions within the triplet manifold. Triplet lifetimes at low temperatures of 30 and 200–600 μs are found for the platinum and palladium polymers, respectively.
Semi-automated vs manually controlled dynamic facades: assessment through a field study on multi-domain occupant satisfaction (2023)

Occupant satisfaction and acceptance with automated control strategies for dynamic façades is currently a barrier to the upscale of these systems. Building owners, designers and occupants are often unconvinced that an automated control strategy for dynamic façades could really be beneficial for building energy efficiency and occupant satisfaction. Previous work has indicated that an integrated multi-domain approach is required for capturing the influence of façades on occupants. The aim of this paper is to provide new knowledge on whether dynamic automated facades with user override (semi-automated) can outperform manually operated facades in terms of occupant multi-domain satisfaction. Occupant interaction, discomfort, satisfaction and indoor environmental quality were monitored in two different scenarios: one where the façade blinds were automatically controlled, aiming at maximising daylight and outdoor view access whilst mitigating glare, and one in which the façade blinds were manually controlled by the occupants. Results showed that when the façade was controlled by a semi-automated strategy, occupant satisfaction was higher (especially in the thermal environment), despite occupants reported a higher number of discomfort events due to lack of daylight and access to outdoor view. However, to increase occupant acceptance, a better prediction of occupant glare to prevent visual discomfort and maximise daylight and view is necessary.
Secure Multiparty Computation for Privacy-Preserving Data Mining (2009)

In this paper, we survey the basic paradigms and notions of secure multiparty computation and discuss their relevance to the field of privacy-preserving data mining. In addition to reviewing definitions and constructions for secure multiparty computation, we discuss the issue of efficiency and demonstrate the difficulties involved in constructing highly efficient protocols. We also present common errors that are prevalent in the literature when secure multiparty computation techniques are applied to privacy-preserving data mining. Finally, we discuss the relationship between secure multiparty computation and privacy-preserving data mining, and show which problems it solves and which problems it does not.
Optimization of the Conductivity and Passivity Properties of Passive Films on Stainless Steels used as Bipolar Plates in PEFC (2009)

The parameters responsible for electrical contact resistance between a stainless steel bipolar plate and a carbon support in a PEFC has been investigated. Roughness of the bipolar plate is useful but its topography should be adapted to the type of used GDL. Bulk composition of the alloy also plays a role, because it defines the quantity of alloying elements susceptible to participate to the passive film growth, but this role appears secondary. Indeed, passivation pre-treatment can deeply modify both structure and composition of the passive layer as investigated on AISI 316L and 904L steels, until reducing the initial electrical contact resistance at a level comparable to graphite. A low-cost surface treatment could thurs represent a good compromise between using as-received stainless steel plates and deposition precious metals. Compared to bright annealed state, initial ECR is divided by a factor 20 but raised slightly after 500 hours of operation.
Recursive projection-aggregation decoding of Reed-Muller codes (2019)

We propose a new class of efficient decoding algorithms for Reed-Muller (RM) codes over binary-input memoryless channels. The algorithms are based on projecting the code on its cosets, recursively decoding the projected codes (which are lower-order RM codes), and aggregating the reconstructions (e.g., using majority votes). We further provide extensions of the algorithms using list-decoding. We run our algorithm for AWGN channels and Binary Symmetric Channels at the short code length ($\le 1024$) regime for a wide range of code rates. Simulation results show that in both low code rate and high code rate regimes, the new algorithm outperforms the widely used decoder for polar codes (SCL+CRC) with the same parameters. The performance of the new algorithm for RM codes in those regimes is in fact close to that of the maximal likelihood decoder. Finally, the new decoder naturally allows for parallel implementations.
PPAR-γ Activation As an Anti-inflammatory Therapy for Respiratory Virus Infections (2010)

Newly emerged influenza viruses have attracted extensive attention due to their high infectivity, proinflammatory actions, and potential to induce worldwide pandemics. Frequent mutations and gene reassortments between viruses complicate the development of protective vaccines and antiviral therapeutics. In contrast, targeting the host response for the development of novel cost-effective, broad-based prophylactic or therapeutic agents holds greater promise. Since inflammation often parallels the development of productive immune responses, virus-induced pulmonary inflammation and injury represents an additional challenge to the development of broad-based immunotherapeutics. Excessive inflammatory responses to respiratory viruses, also known as "cytokine storm," are largely due to immune dysregulation that manifests as proinflammatory cytokine secretion. In addition to modulating lipid and glucose metabolism, peroxisome proliferator-activated receptors (PPAR) play important roles in antagonizing core inflammatory pathways such as NF-kappaB, AP1, and STAT. Their role in regulating inflammatory responses caused by pulmonary pathogens is receiving increasing attention, setting the stage for the discovery of novel applications for anti-diabetic and lipid-lowering drugs. This review focuses on the potential use of PPAR-gamma agonists to downregulate the inflammatory responses to respiratory virus-related pulmonary inflammation.
Advanced Analysis and Seismic Design of Concrete-Filled Steel Tube Structures (2015)

This paper will focus on aspects of the advanced analysis and underlying behavior of composite structures with concrete-filled steel tube (CFT) columns. Through a detailed examination of the results of a suite of full-scale slender CFT beam-column tests, insight into the cyclic behavior of such members is gained, specifically pertaining to local buckling of the steel tube and the plastic hinge length. Modeling techniques, which capture these behaviors, are introduced and incorporated into a general purpose distributed plasticity fiber based beam element formulation. The model is found to be capable of capturing the observed behavior and producing accurate results.
Toward an Automated Measure of Social Engagement for Children With Autism Spectrum Disorder—A Personalized Computational Modeling Approach (2020)

Social engagement is a key indicator of an individual's socio-emotional and cognitive states. For a child with Autism Spectrum Disorder (ASD), this serves as an important factor in assessing the quality of the interactions and interventions. So far, qualitative measures of social engagement have been used extensively in research and in practice, but a reliable, objective, and quantitative measure is yet to be widely accepted and utilized. In this paper, we present our work on the development of a framework for the automated measurement of social engagement in children with ASD that can be utilized in real-world settings for the long-term clinical monitoring of a child's social behaviors as well as for the evaluation of the intervention methods being used. We present a computational modeling approach to derive the social engagement metric based on a user study with children between the ages of 4 and 12 years. The study was conducted within a child-robot interaction setting that targets sensory processing skills in children. We collected video, audio and motion-tracking data from the subjects and used them to generate personalized models of social engagement by training a multi-channel and multi-layer convolutional neural network. We then evaluated the performance of this network by comparing it with traditional classifiers and assessed its limitations, followed by discussions on the next steps toward finding a comprehensive and accurate metric for social engagement in ASD.
Overproduction, purification and crystallization of PfTic22, a component of the import apparatus from the apicoplast ofPlasmodium falciparum (2012)

Tic22 is a component of the protein-import apparatus of the chloroplasts of plants and algae and the apicoplasts of the Apicomplexa, a large group of organisms that includes the parasites that cause malaria. Tic22 is important for protein import into these organelles and for organelle biogenesis. It lies between the two membranes of chloroplasts, making interactions with components of both the TIC and TOC complexes. In the apicoplast, it is predicted to be located between the inner two membranes and to play a similar role in import. Although Tic22 is ubiquitous, its function is as yet uncertain. Tic22 from Plasmodium falciparum was therefore overproduced, purified and crystallized. A data set extending to 2.15 Å resolution has been collected from a crystal containing selenomethionine-labelled protein and structure determination is under way.