gebhart/patrepeval huggingface dataset:
Analysis and Simulation of the IEEE 802.11ay Single-Carrier PHY (2018)

IEEE 802.11ay is an amendment that enables enhanced throughput for IEEE 802.11 systems operating in the license-exempt 60 GHz band. By specifying advanced physical layer (PHY) features such as channel bonding and aggregation, multiple input multiple output (MIMO) transmission, and non-uniform modulation constellation, IEEE 802.11ay supports a maximum data rate of 100 Gb/s, making it an amendment of great interest for applications as diverse as wireless virtual reality (VR) and backhauling. In this paper, we provide a description and analysis of certain fundamental elements of the single-carrier (SC) PHY defined by IEEE 802.11ay. Among the topics that are discussed are the new frame format, modulation and coding schemes (MCSs), and beamforming training field defined in the amendment. Simulation results of key aspects for the topics covered are presented.
Distinct β-Arrestin- and G Protein-dependent Pathways for Parathyroid Hormone Receptor-stimulated ERK1/2 Activation (2006)

Parathyroid hormone (PTH) regulates calcium homeostasis via the type I PTH/PTH-related peptide (PTH/PTHrP) receptor (PTH1R). The purpose of the present study was to identify the contributions of distinct signaling mechanisms to PTH-stimulated activation of the mitogen-activated protein kinases (MAPK) ERK1/2. In Human embryonic kidney 293 (HEK293) cells transiently transfected with hPTH1R, PTH stimulated a robust increase in ERK activity. The time course of ERK1/2 activation was biphasic with an early peak at 10 min and a later sustained ERK1/2 activation persisting for greater than 60 min. Pretreatment of HEK293 cells with the PKA inhibitor H89 or the PKC inhibitor GF109203X, individually or in combination reduced the early component of PTH-stimulated ERK activity. However, these inhibitors of second messenger dependent kinases had little effect on the later phase of PTH-stimulated ERK1/2 phosphorylation. This later phase of ERK1/2 activation at 30-60 min was blocked by depletion of cellular beta-arrestin 2 and beta-arrestin 1 by small interfering RNA. Furthermore, stimulation of hPTH1R with PTH analogues, [Trp1]PTHrp-(1-36) and [d-Trp12,Tyr34]PTH-(7-34), selectively activated G(s)/PKA-mediated ERK1/2 activation or G protein-independent/beta-arrestin-dependent ERK1/2 activation, respectively. It is concluded that PTH stimulates ERK1/2 through several distinct signal transduction pathways: an early G protein-dependent pathway meditated by PKA and PKC and a late pathway independent of G proteins mediated through beta-arrestins. These findings imply the existence of distinct active conformations of the hPTH1R responsible for the two pathways, which can be stimulated by unique ligands. Such ligands may have distinct and valuable therapeutic properties.
Association between Bone Mineral Density and Incidence of Breast Cancer (2013)

This study provides additional support for an inverse association between BMD and the risk of breast cancer.
CCDC 610587: Experimental Crystal Structure Determination (2008)

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
Atomistic simulations of α-Fe/Nd2Fe14B magnetic core/shell nanocomposites with enhanced energy product for high temperature permanent magnet applications (2020)

Nd 2 Fe 14 B has generated significant interest since its discovery in the 1980s due to its impressive energy density, which makes it a prime candidate for use in permanent magnet applications. Its performance is known to suffer greatly at the high temperatures required for motor applications around 450K. Core/shell nanocomposites provide a potential route to improve material performance by combining the highly anisotropic permanent magnet with a material with high moment and high Curie temperature. We have used an atomistic spin model to investigate the magnetic properties of Nd2Fe14B with α-Fe in a core/shell nanostructure. We find that at typical motor operating temperatures, increasing α-Fe content reduces the coercivity of the system while enhancing the saturation magnetization. The overall effect is that an improvement in BHmax is seen with increasing α-Fe up to an optimal value of 70vol.%. This property of core/shell nanostructures would make them a suitable substitute for pure Nd2Fe14B while simultaneously lowering the raw material cost of the permanent magnet component of high-performance motors.
In silico microRNA identification from paprika (Capsicum annuum) ESTs (2009)

Abstract A total of 33,311 Expressed Sequence Tags (EST) of paprika were mined from the GenBank EST database. The redundancy of the EST sequences was removed using CAP3 and it resulted 4,541 contigs 8,539 singletons as nonredundant data sets. The microRNAs were predicted using the program miRNAfinder. This program predicted a total of 85 miRNAs miRNAs. Another study was carried out to find the homologes miRNA using blast based tool named “miRseeK’ A total of 13 miRNAs with significant similarity with the plant miRNAs were obtained from paprika ESTs. The targets of the predicted miRNAs were found using the program miRU2. Findings suggest that most miRNAs play an important role in plant development, signal transduction, protein degradation and in response to environmental stress. The miRNAs were found to be perfectly or nearly complementary to its target mRNAs.
Additive/synergistic efficacy of zoledronic acid and LBH589 in the spheroid-based cellular angiogenesis assay (2009)

e14627 Background: The compounds Zoledronic acid (ZA) and LBH589 (histon deactetylase (HDAC) inhibitor) have shown in previous experiments antitumoral and antiangiogenic effects. Aim of this study was to determine their ability to inhibit VEGF-A induced endothelial cell (EC) sprouting and to observe potential additive/synergistic effects of the combination ZA and LBH589 in the spheroid-based cellular 3D angiogenesis assay. Methods: HUVEC spheroids were embedded in a 3D collagen gel, stimulated with VEGF-A [25 ng/ml] and treated for 24h with different concentrations of ZA alone or in combination with LBH589. Sprouting intensity of EC spheroids was quantitated by an image analysis system determining the cumulative sprout length per spheroid using an inverted microscope and digital imaging software. The mean of the cumulative sprout length of 10 randomly selected spheroids was analyzed as an individual data point. Results: Before testing the compounds in combination the single IC 50 values for ZA (42 μM) and LBH589 (2.9 μM) were determined. The IC 50 of ZA has to be considered with caution because of the low inhibitory effect which did not reach basal sprouting levels. In the first combination experiment a dilution series of ZA was tested in combination with a constant LBH589 concentration [2.9 μM, IC 50 value as determined previously]. The combination of ZA with LBH589 was ∼330 fold more effective in the inhibition of EC sprouting than ZA alone [0.58 μM compared to 190 μM]. However, the sprouting intensity in the combination of LBH589 and ZA was very low. Therefore the experiment was repeated with a dilution series of ZA in combination with a constant LBH589 concentration that showed no inhibition of EC sprouting previously (1 μM). The second combination experiment revealed IC 50 values of 1300 μM for ZA alone and 1.5 μM in combination with LBH589 [1 μM]. The combination LBH589 and ZA is again ∼870 fold more effective in the inhibition of EC sprouting than ZA alone. Conclusions: Our results indicate a very strong synergistic effect of the combination ZA and LBH589 in the spheroid-based angiogenesis assay. No significant financial relationships to disclose.
Polymerization ofN, N-Dimethylaminopropyl-Acrylamide Through Hydrogen Transfer Induced by the Propagation of the Polyacrolein Anion (1987)

Abstract The anionic polymerization of acrolein (AL) with N, N-dimethylamino-propylacrylamide (DMAPA) in the presence of water was investigated in tetrahydrofuran, benzene, and ethanol at 0°C in a nitrogen atmosphere. The resulting polymers were found to be essentially vinyl polymers with one DMAPA attached and an aldehyde side chain. From observations of the polymerization process by 1H NMR, we find that polymerization was initiated by the hydroxyl anion formed in the thermodynamic equilibrium between the amine of DMAPA and water. The hydrogen transfer reaction of DMAPA was caused by the propagating poly-AL anion. On the other hand, the monomer reactivity ratios and the Q2-e2values of DMAPA were determined by the free-radical copolymerization of styrene (St, M1) with DMAPA and AIBN as initiator.
Noise analysis for CCD-based ultraviolet and visible spectrophotometry (2015)

We present the results of a detailed analysis of the noise behavior of two CCD spectrometers in common use, an AvaSpec-3648 CCD UV spectrometer and an Ocean Optics S2000 Vis spectrometer. Light sources used include a deuterium UV/Vis lamp and UV and visible LEDs. Common noise phenomena include source fluctuation noise, photoresponse nonuniformity, dark current noise, fixed pattern noise, and read noise. These were identified and characterized by varying light source, spectrometer settings, or temperature. A number of noise-limiting techniques are proposed, demonstrating a best-case spectroscopic noise equivalent absorbance of 3.5×10(-4) AU for the AvaSpec-3648 and 5.6×10(-4) AU for the Ocean Optics S2000 over a 30 s integration period. These techniques can be used on other CCD spectrometers to optimize performance.
Study of excited-state dipole reorientation in liquids by a Dc conductivity method with subnanosecond time resolution (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStudy of excited-state dipole reorientation in liquids by a Dc conductivity method with subnanosecond time resolutionS. N. Smirnov and Charles L. BraunCite this: J. Phys. Chem. 1992, 96, 24, 9587–9591Publication Date (Print):November 1, 1992Publication History Published online1 May 2002Published inissue 1 November 1992https://pubs.acs.org/doi/10.1021/j100203a003https://doi.org/10.1021/j100203a003research-articleACS PublicationsRequest reuse permissionsArticle Views57Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
A light-triggered molecular switch for an efficient OFET-based organic memory device (2022)

An efficient OFET-based memory is designed using spiropyran molecular switch operating via two complementary mechanisms: reversible photoisomerization and light-induced electron transfer involving [Cr(C 2 O 4 ) 3 ] 3− counterion.
Molecular collisions coming into focus (2014)

The Stark deceleration method exploits the concepts of charged particle accelerator physics to produce beams of neutral polar molecules with an almost perfect quantum state purity, a tunable velocity and a narrow velocity distribution. These monochromatic molecular beams offer interesting perspectives for precise studies of molecular scattering processes, in particular when used in conjunction with state-of-the-art laser-based detection techniques such as velocity map imaging. Here, we describe crossed beam scattering experiments in which the Stark deceleration method is combined with the velocity map imaging technique. The narrow velocity spread of Stark-decelerated molecular beams results in scattering images with unprecedented velocity and angular resolution. We demonstrate this by resolving quantum diffraction oscillations in state-to-state inelastic differential scattering cross sections for collisions between NO radicals and rare gas atoms. We describe the future prospects of this "best-of-two-worlds" combination, ranging from scattering studies at low collision energies to bimolecular scattering using two decelerators, and discuss the challenges that lie ahead to achieve these goals.
Linkers in fragment-based drug design: an overview of the literature (2023)

The authors believe that fragment linking offers key advantages for compound design, particularly for the design of bivalent inhibitors linking two distinct pockets of the same or different subunits. On the other hand, more studies are needed to increase the potential of protein-templated approaches in FBDD. Important computational tools such as structure-based de novo software are emerging to select suitable linkers. Fragment linking will undoubtedly benefit from developments in computational approaches and machine learning models.
Defeating the trade-off between process complexity and electrical performance with vertical zinc oxide transistors (2012)

Short-channel devices can show high performance, but typically have difficult processing and alignment steps. We show here a simple low-temperature process to produce sub-micrometer-channel zinc-oxide thin-film transistors. The thickness of the gate metal defines the channel length, while a combination of conformal and non-conformal depositions create the channel and electrodes. Layer-to-layer alignment is noncritical. With mobility values ten times greater than amorphous silicon, high on/off current ratios at low voltage, good yield, and good thermal sinking in operation, these vertical transistors unite the performance of metal oxide semiconductors with the advantages of short-channel devices.
High power laser mode conversion with volume phase elements recorded in PTR glass (2019)

The manipulation of a laser’s transverse profile is of great interest for many applications. The most common and simple approach to beam shaping is by the use of optical phase masks. Conventional phase masks fabricated by surface profiling using spatially selective etching or deposition are easily damaged and limit high energy applications. We have shown in past work, that it is possible to create different phase profiles in the volume of photo-thermorefractive (PTR) glass, which unlike conventional phase mask materials has a high damage threshold that can withstand high peak and average powers. Here we present an approach for mode conversion of a high power fiber laser system using two different types of phase masks fabricated by encoding phase profiles into volume Bragg gratings. These holographic phase masks (HPMs) can successfully introduce wavefront change and achieve high diffraction efficiency (based on wavelength and the grating strength) for a broad range of wavelengths by tuning the element to the gratings Bragg condition. The first element had a grayscale vortex phase profile for HG<sub>1</sub> conversion. The second had a binary four-sector phase profile, and was capable to perform fundamental mode conversion to a TEM<sub>01</sub>, TEM<sub>10</sub>, or TEM<sub>11</sub>. Mode conversion efficiency and thermal stress on each type of phase element were investigated using a 150 W of continuous wave power with a TEM<sub>00</sub> profile Yb:fiber laser.
Raman Scattering from SingleCrystal KC60 (1996)

Raman scattering is used to analyse phase transitions and structures in KC60 crystals. The doping of the crystals was performed at 450 K and studied in situ by observing the Ag(2) pinch mode in the Raman spectrum. The crystals were homogeneously doped at least up to the penetration depth of the laser used. Slow cooling from 450 K to room temperature showed clearly the phase separation of KC60 into C60 and K3C60 at 420 K. With fast cooling rates, dramatic changes in the Raman spectra were observed and interpreted as a phase transition to an orthorhombic structure as previously for RbC60. Quenching experiments for KC60 showed that a fraction of KC60 could be retained, but it dissolved rapidly even at temperatures below room temperature.
Preservation of piecewise-linear Lyapunov function under Pad&#x00E9; discretization (2011)

In this paper we show that certain piecewise-linear Lyapunov functions are preserved for LTI systems under Padé approximations. In particular, we present a simple method to find a piecewise-linear Lyapunov function that is so preserved under the Padé discretization of any order and sampling time. This result may be of interest in the discretisation of switched linear systems for both simulation and control design.
N-gram of Orthographic Syllable Indexing for Khmer Information Retrieval System (2014)

In the conventional approach of text retrieval, words are usually used as the unit of indexing. However, in many Asian languages such as Chinese, Japanese and Thai, word segmentation is still an open issue and still actively addressed by many researchers to achieve high segmentation accuracy especially when dealing with the out-of-vocabulary words. This issue also occurs in Khmer, and it affects Khmer infor- mation retrieval (IR) . To solve the issue, we propose an indexing approach based on n-grams of Khmer orthographic syllable instead of words. The experiments show that the proposed approach outperforms the conventional word based indexing approach. Therefore, n-grams of orthographic syllables can be an alternative to words in case of Khmer IR.
Stabilization of type I topoisomerase-DNA covalent complexes by actinomycin D. (1988)

The activity of the endogenous DNA topoisomerase type I (EC 5.99.1.2) can be quantified in situ by determining how efficiently the enzyme is trapped in a covalent complex with DNA upon lysis of nuclei with detergents. In this way, we can measure relative levels of topoisomerase binding to DNA at native sites in chromatin. Since the majority of topoisomerase I is localized in the nucleolus at rRNA genes, we have evaluated how low levels of actinomycin D, which terminate transcription of rRNA genes, affect the activity of topoisomerase I. In vivo, as well as in vitro with purified topoisomerase I, we have found that drug treatment extends the half-life of the covalent topoisomerase-DNA complex. Actinomycin D stabilizes the nicked intermediate in the cleavage and resealing reaction but otherwise does not significantly alter the strand-passing ability of topoisomerase I. Sequence-specific cleavages by topoisomerase I were stimulated by actinomycin D at identical sequences recognized by the enzyme in the absence of drug. The localization of topoisomerase I in the nucleolus, coupled with the observation that transcription in this organelle is highly sensitive to actinomycin D and camptothecin treatment, leads us to propose that topoisomerase I contributes to actinomycin D inhibition of transcription.
Pyridoxine Is Not Effective to Prevent Hand-Foot Syndrome Associated With Capecitabine Therapy: Results of a Randomized, Double-Blind, Placebo-Controlled Study (2010)

Pyridoxine is not effective in prevention of capecitabine-associated HFS.
Thermo-optic vertical coupler switches using hybridpolymer/silica integration technology (2000)

A hybrid integration concept has been investigated which combines the advantages of ultra-low loss silica waveguides and low power consumption polymer thermo-optic switches. A 1×2 vertical coupler type switch (VCS) has been realised. Preliminary results exhibited a crosstalk of &lt; –23 dB, an insertion loss of 3.5 dB (at 1550 nm) and a switching power of &lt; 80 mW.
Crack Penetration, Deflection or Arrest? (2017)

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Density Equalizing Distortion of Large Geographic Point Sets (2009)

Visualizing large geo-demographical datasets using pixel-based techniques involves mapping the geospatial dimensions of a data point to screen coordinates and appropriately encoding its statistical value by color. The analysis of such data presents a great challenge. General tasks involve clustering, categorization, and searching for patterns of interest for sociological or economic research. Available visual encodings and screen space limitations lead to over-plotting and hiding of patterns and clusters in densely populated areas, while sparsely populated areas waste space and draw the attention away from the areas of interest. In this paper. two new approaches (RadialScale and AngularScale) are introduced to create density-equalized maps, while preserving recognizable features and neighborhoods in the visualization . These approaches build the core of a multi-scaling technique based on local features of the data described as local minima and maxima of point density. Scaling is conducted several times around these features, which leads to more homogeneous distortions. Results are illustrated using several real-world datasets. Our evaluation shows that the proposed techniques outperform traditional techniques as regard the homogeneity of the resulting data distributions and therefore build a more appropriate basis for analytic purposes.
Collector amplitude modulation of the class E tuned power amplifier (1984)

In the class <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">E</tex> high-efficiency switching-mode tuned power amplifier, the RF output amplitude is almost exactly a linear function of the collector dc supply voltage, since conduction angles and wave shapes are not changed by the dc supply voltage. Thus the RF output can be amplitude-modulated by varying the dc supply voltage in accordance with desired amplitude-modulation (AM) envelope. Deviations from the ideal linear modulation characteristic are caused by: transistor saturation voltage; RF feedthrough from the driver via <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">C_{cb}</tex> ; nonunity transmission of the ac modulating signal into the amplifier through the nonzero inductance of the collector shuntfeed RF choke; and differences in the magnitudes and delay times, of the RF transmission function through the RF output network, of three different frequencies: lower sideband, carrier, and upper sideband. Design criteria are given, to hold the modulation distortion below a limit chosen by the designer. Experimental results agree well with analytical predictions. Distortion of the modulation envelope can easily be held below 1 percent.