gebhart/patrepeval huggingface dataset:
PROLIFERATION OF NEONATAL PORCINE ISLET BETA CELLS AND XENOANTIGEN EXPRESSION. (2000)

Vizzardelli, Caterina1; Molano, R. Damaris1; Pileggi, Antonello1; Berney, Thierry1; Cattan, Pierre1; Ricordi, Camillo1; Inverardi, Luca1 Author Information
Relation of ocular trauma to cortical, nuclear, and posterior subcapsular cataracts: the Beaver Dam Eye Study (2002)

The data provide evidence of a possible association between self reported ocular trauma and posterior subcapsular cataract.
Postprandial Hyperglycemia Corrected by IGF-I (Increlex®) in Laron Syndrome (2012)

Postprandial hyperglycemia is a metabolic consequence of chronic IGF-I deficiency. The beneficial effect of IGF-I replacement therapy may be ascribable to improved postprandial transfer of glucose.
Detecting Socio-Economic Impact of Cultural Investment Through Geo-Social Network Analysis (2018)

Taking advantage of nearly 4 million transition records for three years in London from a popular location-based social network service, Foursquare, we study how to track the impact and measure the effectiveness of cultural investment in small urban areas. We reveal the underlying relationships between socio-economic status, local cultural expenditure, and network features extracted from user mobility trajectories. This research presents how geo-social and mobile services more generally can be used as a proxy to track local changes as government financial effort is put in developing urban areas, and thus gives evidence and suggestions for further policy-making and investment optimization.
Neurobiologic Foundations of Mood Disorders (2008)

This chapter contains sections titled: Nomenclature Genetics Pathogenic Mechanisms Intracellular Signal Transduction Pathways and Growth Factors Conclusion References
An Adaptive Method for Flexible Configurations of Single-Arm Cluster Tools: Modeling and Scheduling (2022)

Traditionally, process modules in cluster tools can execute a single operation only. With the rapid development of equipment design, recent cluster tools tend to have multi-functional process modules (MPMs) serving for processing multiple operations together in a single module. However, the different function settings of MPMs make the tool configuration various such that it is difficult to determine a schedule plan. Meanwhile, with different wafer processing parameters, a reasonable function setting for MPM can result in an excellent schedule so as to maximize the productivity. Thus, to solve the scheduling problem of a single-arm cluster tool with MPMs, a timed Petri net model is established to describe the behaviors of the system. Based on the model, two algorithms are developed to calculate the makespan for completing a given number of wafers. Then, an adaptive schedule method is presented to set the functions of MPMs to minimize the makespan. Finally, experimental results show the efficiency and effectiveness of the proposed method.
Simulation of spreading depolarization trajectories in cerebral cortex: Correlation of velocity and susceptibility in patients with aneurysmal subarachnoid hemorrhage (2017)

In many cerebral grey matter structures including the neocortex, spreading depolarization (SD) is the principal mechanism of the near-complete breakdown of the transcellular ion gradients with abrupt water influx into neurons. Accordingly, SDs are abundantly recorded in patients with traumatic brain injury, spontaneous intracerebral hemorrhage, aneurysmal subarachnoid hemorrhage (aSAH) and malignant hemispheric stroke using subdural electrode strips. SD is observed as a large slow potential change, spreading in the cortex at velocities between 2 and 9 mm/min. Velocity and SD susceptibility typically correlate positively in various animal models. In patients monitored in neurocritical care, the Co-Operative Studies on Brain Injury Depolarizations (COSBID) recommends several variables to quantify SD occurrence and susceptibility, although accurate measures of SD velocity have not been possible. Therefore, we developed an algorithm to estimate SD velocities based on reconstructing SD trajectories of the wave-front's curvature center from magnetic resonance imaging scans and time-of-SD-arrival-differences between subdural electrode pairs. We then correlated variables indicating SD susceptibility with algorithm-estimated SD velocities in twelve aSAH patients. Highly significant correlations supported the algorithm's validity. The trajectory search failed significantly more often for SDs recorded directly over emerging focal brain lesions suggesting in humans similar to animals that the complexity of SD propagation paths increase in tissue undergoing injury.
Book Review of Modern Biooxidation: Enzymes, Reactions and Applications (2008)

ADVERTISEMENT RETURN TO ISSUEPREVBook ReviewNEXTADDITION / CORRECTIONThis article has been corrected. View the notice.Book Review of Modern Biooxidation: Enzymes, Reactions and ApplicationsPatrick C. CirinoView Author Information Pennsylvania State UniversityCite this: J. Am. Chem. Soc. 2008, 130, 19, 6299Publication Date (Web):April 18, 2008Publication History Received24 October 2007Published online18 April 2008Published inissue 1 May 2008https://doi.org/10.1021/ja077021eCopyright © 2008 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views133Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (62 KB) Get e-AlertsSUBJECTS:Biotransformation,Peptides and proteins,Pharmaceuticals,Regeneration Get e-Alerts
Design Procedures for Marine Renewable Energy Foundations (2015)

Abstract The Geotechnics Sub-Committee of the American Society of Civil Engineers (ASCE) Coasts, Oceans, Ports, and Rivers Institute (COPRI) Marine Renewable Energy (MRE) Committee is preparing a guide document for marine renewable energy foundations. That guide would use standard design codes for fixed foundations and mooring anchors in API RP 2GEO and DNV. The static method of computing axial pile capacity described in API RP 2GEO (2011) is generally used to compute ultimate compressive and tensile capacities of pipe piles driven to a given penetration. Lateral soil resistance –pile deflection (p-y) data for clays and sands are usually developed using procedures proposed by Matlock (1970) and O'Neill and Murchison (1983), respectively, and outlined in API RP 2GEO (2011). Marine energy foundations are unique in several ways. Axial pile capacity computations are usually based on a reasonable lower bound, in contrast to the soil resistance to driving, which is based on a reasonable upper bound. For structures supporting wind turbines, however, underestimating (or overestimating) the soil stiffness could require a change in turbine operation and a loss of power production. Although the classical API method is recognized as an appropriately conservative design method for offshore pile foundations, a prediction method is more well suited for structures supporting wind turbines, such as the CPT-based methods for predicting pile capacity in granular soils presented in API RP 2GEO (2011). If a prediction method is used to compute the soil resistance to driving, the evaluation of pile drivability may be overly conservative. Ageing in both clay and sand should also be taken into account. Wind turbines are often supported on large diameter monopiles. The applicability of the p-y data for such large diameter piles needs to be verified. Finally, marine renewable energy generated by in-stream hydrokinetics, ocean thermal energy conversion, and wave energy converters may be floating devices usually anchored to the seafloor. There are uncertainties in the design and installation of these anchors, which become critical for large sustained tensile loads that may degrade due to creep and cyclic loading.
Selective leaching of uranium from uranium-contaminated soils (1993)

Three soils and a sediment contaminated with uranium were used to determine the effectiveness of sodium carbonate and citric acid leaching to decontaminate or remove uranium to acceptable regulatory levels. The objective was to selectively extract uranium using a soil washing/extraction process without seriously degrading the soil`s physicochemical characteristics or generating a secondary waste form that would be difficult to manage and/or dispose of. Two of the soils were surface soils from the DOE facility formerly called the Feed Materials Production Center (FMPC) at Fernald, Ohio. One of the soils is from near the Plant 1 storage pad and the other soil was taken from near a waste incinerator used to burn low-level contaminated trash. The third soil was a surface soil from an area formally used as a landfarm for the treatment of spent oils at the Oak Ridge Y-12 Plant. The sediment sample was material sampled from a storm sewer sediment trap at the Oak Ridge Y-12 Plant. Uranium concentrations in the Fernald soils ranged from 450 to 550 {mu}g U/g of soil while the samples from the Y-12 Plant ranged from 150 to 200 {mu}g U/g of soil.
Mechanisms Underlying Tolerance after Long-Term Benzodiazepine Use: A Future for Subtype-Selective Receptor Modulators? (2012)

Despite decades of basic and clinical research, our understanding of how benzodiazepines tend to lose their efficacy over time (tolerance) is at least incomplete. In appears that tolerance develops relatively quickly for the sedative and anticonvulsant actions of benzodiazepines, whereas tolerance to anxiolytic and amnesic effects probably does not develop at all. In light of this evidence, we review the current evidence for the neuroadaptive mechanisms underlying benzodiazepine tolerance, including changes of (i) the GABA(A) receptor (subunit expression and receptor coupling), (ii) intracellular changes stemming from transcriptional and neurotrophic factors, (iii) ionotropic glutamate receptors, (iv) other neurotransmitters (serotonin, dopamine, and acetylcholine systems), and (v) the neurosteroid system. From the large variance in the studies, it appears that either different (simultaneous) tolerance mechanisms occur depending on the benzodiazepine effect, or that the tolerance-inducing mechanism depends on the activated GABA(A) receptor subtypes. Importantly, there is no convincing evidence that tolerance occurs with α subunit subtype-selective compounds acting at the benzodiazepine site.
1-bit RF-MEMS-reconfigurable elementary cell for very large reflectarray (2010)

This paper presents a reconfigurable MEMS based radiating element for the realization of a beam steering reflectarray. The elementary cell consists of a square patch slot-coupled to a phase shifting circuit with 1-bit phase resolution (0°/180°), operating at 76.5GHz. Reconfigurability is obtained with RF MEMS switches integrated in the elementary cell. The problem of reconfigurability of reflectarray antennas based on RF MEMS technology is addressed within the European FP7 project called ARASCOM. Since thousands of reconfigurable elementary cells are employed, reducing the number of tuneable components is of fundamental importance for the practical realization of the reflectarray. A dramatic reduction of the number of tuneable devices is shown to be achievable without performance degradation by a proper architecture based on 1-bit digital phase shifting. In this paper the elementary cell design and the reflectarray fabrication technology are illustrated in some details showing the feasibility of the proposed approach.
P3B-6 Implications of Mode Conversion on Transcranial Ultrasound Imaging (2007)

Transcranial ultrasound sector images are affected by a "streak artifact": two dark streaks stem radially from the apex to the maximal depth of the scan at particular angles, limiting the effective field of view and diagnostic confidence. The aim of this paper is to investigate experimentally the angle dependency of ultrasound transmission through the skull in order to understand and try to reduce this artifact. It is shown that the streaks are a consequence of the angle-dependent amplitude transmission coefficient at fluid-solid interfaces such as the interfaces between the skull bone and the surrounding fluid-like soft tissues. At a critical incidence angle of about 27deg, no ultrasound wave can cross the soft tissue-skull interfaces, which explains the presence of the streaks. At higher incidence angles, mode conversion from longitudinal to transverse waves occurs in the skull, and then back to longitudinal into the brain. The influence of the incidence angle on the distortion of the transmitted beam is also qualitatively assessed. Implications for transcranial imaging are discussed.
Self management of oral anticoagulation with the IN Ratio system: impact of a structured teaching program on patient??s knowledge of medical background and procedures (2004)

The structured training program INRatio appears to be an appropriate instrument for instruction of INR self management. In comparison with baseline knowledge, the percentage of correctly answered questions was twice as high directly after the end of training and remained at a high level of >90% for at least 6 weeks.
Serum erythropoietin levels and blood component therapy after autologous bone marrow transplantation: implications for erythropoietin therapy in this setting. (1992)

To determine the potential impact of recombinant human erythropoietin (EPO) therapy in patients undergoing autologous bone marrow transplantation (BMT) and colony-stimulating factor therapy, we assayed endogenous serum EPO levels and noted blood transfusion requirements in relapsed non-Hodgkin's lymphoma patients treated with high-dose chemo-radiation therapy and autologous BMT. Hematocrit and reticulocyte counts were determined daily, and hematocrit was maintained in the 25-30% range by transfusion according to criteria established by our hospital transfusion committee. EPO levels were measured by radioimmunoassay and were determined at baseline, throughout therapy, and 2 and 3 months after BMT. Serum EPO levels increased more than 25-fold above baseline in most subjects after initiating chemoradiation therapy. No correlation was noted between serum EPO and hematocrit, reticulocyte count or serum creatinine. Total red blood cell units transfused ranged from 4 to 15 (mean 7.7). Mean total donor exposures (red blood cell plus platelet units transfused) were 83.6 units (range 16-175). Serum EPO levels increased early in the course of preparation for autologous BMT and remained elevated for at least 2-3 weeks thereafter although at a lower level. Red blood cell transfusions were required despite very high EPO levels after BMT. Red cell transfusions, moreover, accounted for only 9.2% (69 of 746) of total donor exposures and only 5.8% (42 of 746) of donor exposures during the interval when pharmacologic doses of erythropoietin might be of benefit. In contrast to the potential benefit of colony-stimulating factors such as G-CSF and GM-CSF in BMT, our study suggests limited value for erythropoietin therapy in this setting.
Towards elucidating the radiochemistry of astatine – Behavior in chloroform (2019)

Targeted alpha therapy of disseminated cancer is an emerging technique where astatine-211 is one of the most promising candidate nuclides. Although astatine has been known for over 70 years, its chemistry is still largely unexplored, mainly due to the lack of stable or long-lived isotopes. However, substantial amounts of astatine-211 can be produced in cyclotrons by the bombardment of natural bismuth. The astatine can be recovered from the resulting irradiated target material through either wet extraction or dry-distillation. Chloroform has become an important intermediate solvent for the recovery of astatine after production, especially following dry distillation. In this work, the radiochemistry of astatine in chloroform was investigated using evaporation, solvent extraction, chromatographic methods and molecular modeling. The extraction of astatine in chloroform led to the formation of multiple astatine species, allowing for evaporation of the solvent to dryness without any loss of activity. Radiolysis products of chloroform were shown to play an important role in the speciation of astatine forming both reactive and kinetically stable compounds. It was hypothesized that reactions with chlorine, as well as trichloromethyl hydroperoxide, forming polar astatine compounds are important reactions under the current experimental conditions.
Hopper (2015)

As clusters continue to grow in size and complexity, providing scalable and predictable performance is an increasingly important challenge. A crucial roadblock to achieving predictable performance is stragglers, i.e., tasks that take significantly longer than expected to run. At this point, speculative execution has been widely adopted to mitigate the impact of stragglers. However, speculation mechanisms are designed and operated independently of job scheduling when, in fact, scheduling a speculative copy of a task has a direct impact on the resources available for other jobs. In this work, we present Hopper, a job scheduler that is speculation-aware, i.e., that integrates the tradeoffs associated with speculation into job scheduling decisions. We implement both centralized and decentralized prototypes of the Hopper scheduler and show that 50% (66%) improvements over state-of-the-art centralized (decentralized) schedulers and speculation strategies can be achieved through the coordination of scheduling and speculation.
Practical Web Data Extraction: Are We There Yet? - A Short Survey (2016)

The number of web documents as well as the inherent data and information is growing at a rapid pace. The interest in extracting and utilizing this data is rising likewise. The prospects that are unlocked by Web Data Extraction to its users are as broad as the extensiveness of topics and fields on the Web. The major obstacle is to utilize the available data, contents and processes. Several, mostly older survey papers have already shown developments and approaches to solve Web Data Extraction tasks, but there is a need for a more up-to-date review, showing the latest developments. Additionally when looking from the user perspective, there is still a gap between research results and practical applicability. Available solutions, including research results, commercial products and open source solutions lack certain capabilities or suffer from severe usability issues. This paper therefore gives a short review of the state of the art in Web Data Extraction and relates this to the practical application of these technologies.
Monitoring food intake (2010)

On a busy ward it is easy to miss what patients have eaten at every mealtime. even if you ask them you may not get enough information to judge their intake accurately. yet the consequences of poor intake on an individual's health and wellbeing are well known. it is estimated that four out of ten older patients arrive in hospital malnourished and six out of ten are at risk of becoming malnourished or their situation worsening during their stay ( age Concern 2006 ).
ELECTROMAGNETIC COMPATIBILITY OF WLAN ADAPTERS WITH LIFE-SUPPORTING MEDICAL DEVICES (2011)

This paper investigates the electromagnetic compatibility of 45 critical care medical devices (infusion pumps, defibrillators, monitors, lung ventilators, anesthesia machines and external pacemakers) with various types of wireless local area network (WLAN, IEEE 802.11 b/g, 2.45 GHz, 100 mW) adapters. Interference is evaluated by performing ad-hoc tests according to the ANSI C63.18 recommended practice. The behavior of the devices during the tests was monitored using patient simulators/device testers specific for each device class. Electromagnetic interference cases were observed in three of 45 devices at a maximum distance of 5 cm. In two cases the interference caused malfunctions that may have clinical consequences for the patient. The authors' findings show that the use of these wireless local area network adapters can be considered reasonably safe, although interference may occur if they are operated at very close distance (<10 cm) to the medical devices.
Positive Margins after Cervical Conization and the Predictive Factors of Residual Disease (2004)

Objective : The aim of this study was to evaluate the predictive factors of residual disease for positive conization margins. Methods : Retrospective study was performed in 735 patients treated with bovie electroknife conization at the University Hospital of Kuro between January, 1988 and December, 2003. Of the 735 patients, 81 patients (11.0%) had positive margins after conization. 58 of these 81 patients underwent either immediate reoperation or monitoring with a Pap smear, HPV test, endocervical curettage and colposcopy. Fisher exact test, Trend test were used for statistical analysis. Results : The mean age of the patients was 44.5 years. 27 of 58 patients (46.6%) undergoing conization followed by reoperation had residual lesion in the specimen obtained by reoperation. Severity of lesion was associated with the predictive factors of residual disease (p
Forward Error Correction for WebRTC using FEC FRAME (2013)

WebRTC provides a solution for peer-to-peer streaming between web
applications by leveraging a Real-Time Protocol (RTP) stream between
two clients. This RTP stream is expected to be sent over an UDP
(Universal Datagram Protocol) connection, which by definition has no
built-in reliability. Recently the FEC FRAME Working Group of the IETF
has come up with a framework and technical recommendations for
applying forward error correction (FEC) to unreliable streams. This
framework can be applied to WebRTC with minimal changes to the
specification.
<title>Adaptive watermarking using successive subband quantization and perceptual model based on multiwavelet transform</title> (2002)

This paper presents an adaptive digital image watermarking scheme that uses successive subband quantization (SSQ) and perceptual modeling. Our approach performs a multiwavelet transform to determine the local image properties optimal and the watermark embedding location. The multiwavelet used in this paper is the DGHM multiwavelet with approximation order 2 to reduce artifacts in the reconstructed image. A watermark is embedded into the perceptually significant coefficients (PSC) of the image in each subband. The PSCs in high frequency subbands are selected by setting the thresholds to one half of the largest coefficient in each subband. After the PSCs in each subband are selected, a perceptual model is combined with a stochastic approach based on the noise visibility function to produce the final watermark.