gebhart/patrepeval huggingface dataset:
Serum cathepsin D and its density in men with prostate cancer as new predictors of disease progression (2002)

We examined whether serum levels of cathepsin D (CatD) and its density (CatD-D), which was determined by dividing the serum levels of CatD by the prostate volume, could be used as predictors of the progression and prognosis in patients with prostate cancer. Serum levels of CatD in 40 healthy controls, 70 patients with benign prostatic hypertrophy (BPH) and 80 patients with prostate cancer were measured by a sandwich enzyme immunoassay, and prostate volume was measured using transrectal ultrasonography. The mean levels of CatD and CatD-D in patients with prostate cancer were significantly higher than those in healthy controls and patients with BPH. Furthermore, the CatD and CatD-D levels in prostate cancer patients with metastasis were significantly elevated compared with those in patients without metastasis. Among patients who underwent radical prostatectomy, the levels of CatD and CatD-D in patients with pathologically organ-confined disease were significantly lower than in those with extraprostatic disease. However, the elevated levels of CatD and CatD-D were not significantly associated with the cause-specific survival in prostate cancer patients. These findings suggest that the elevation of CatD or CatD-D could be used as new predictors of disease progression, but not prognosis, in patients with prostate cancer.
Digital optimal control of elastic structure systems. Positioning control of an elastic rotating arm. (1987)

By treating the positioning control problem of a cautilever-type arm rotating horizontally, the digital optimal control problem of an elastic structure system is theoretically and experimentally considered in this study. Especially, a method for examining the influence of spillover due to a finite dimensional approximation of the elastic structure and a calculation delay in the digital control is presented. By the practical development of control equipment and the various control experiments, the usefulness of the proposed design method is verified, and important information about this kind of control is obtained. Furthermore, the influence of the friction in the DC servo-motor is investigated, mainly by digital simulations.
A Facile, Novel Methodology for Preparation of Multilayer Metal/Polymer Composite Films (2007)

Metal/polymer composite multilayer films were prepared from metal complex-containing polymers on reflective substrates through optical interference by irradiating monochromatic light. Transmission electron microscopy (TEM) analyses of the irradiated films revealed that metal nanoparticles generated by photoreduction of metal complexes were aligned in the row with a constant spacing perpendicular to the reflective substrates. The spacing between successive metal layers was controlled by changing wavelength or incident angle of the irradiating light. This technique could be applied to a variety of combinations of metal compounds and polymers.
Prognostic Significance of Telomerase Polymorphism in Non–Small Cell Lung Cancer (2010)

Telomerase functional polymorphism in the hTERT gene may contribute as a prognostic factor in NSCLC patients. Our findings indicate that hTERT genetic variants, by modulating telomere length, may confer an advantage in chemotherapy response. The assessment of telomerase genetic variants could supplement prognosis of survival in the course of NSCLC and may be a promising molecular marker of treatment response in these patients.
Fast and accurate spectral-estimation axial super-resolution optical coherence tomography (2021)

Spectral-estimation OCT (SE-OCT) is a computational method to enhance the axial resolution beyond the traditional bandwidth limit. However, it has not yet been used widely due to its high computational load, dependency on user-optimized parameters, and inaccuracy in intensity reconstruction. In this study, we implement SE-OCT using a fast implementation of the iterative adaptive approach (IAA). This non-parametric spectral estimation method is optimized for use on OCT data. Both in simulations and experiments we show an axial resolution improvement with a factor between 2 and 10 compared to standard discrete Fourier transform. Contrary to parametric methods, IAA gives consistent peak intensity and speckle statistics. Using a recursive and fast reconstruction scheme the computation time is brought to the sub-second level for a 2D scan. Our work shows that SE-OCT can be used for volumetric OCT imaging in a reasonable computation time, thus paving the way for wide-scale implementation of super-resolution OCT.
Relevance of healthcare-associated pneumonia for empirical antibiotic therapy in the Netherlands. (2018)

In the Netherlands, HCAP criteria predict higher amoxicillin non-susceptibility in patients hospitalized with moderate-severe CAP. Although broadening the antibiotic spectrum of empiric treatment reduced the likelihood of non-susceptibility, absolute reductions of non-susceptibility in HCAP patients were too low to justify the universal use of broad-spectrum empirical therapy.No abstract available.
A descriptive analysis of the impact of COVID-19 on Emergency Department attendance and visit characteristics in Singapore (2021)

Abstract Introduction: It is yet to be understood how COVID-19 impacted utilisation of Emergency Department (ED) services in Singapore. This study aimed to describe the changes in attendance of a single ED and corresponding patient visit characteristics and outcomes before and during the COVID-19 period. Methods: In a single-centre retrospective cohort study, we used descriptive statistics to compare ED attendance, patient demographics and visit characteristics during the COVID-19 period (1 January – 28 June 2020) and its corresponding historical period in 2019 (2 January – 30 June 2019). Results: Mean ED attendance decreased from 342 visits/day in the pre-COVID-19 period, to 297 visits/day in the COVID-19 period. This was accompanied by reductions in P1 visits and presentations in nearly every ICD-10-CM diagnosis category except for respiratory-related diseases. We also noted a shift in ED patient case-mix from ‘Non-fever’ cases to ‘Fever’ cases, likely giving rise to two distinct trough-to-peak visit patterns during the pre-Circuit Breaker and Circuit Breaker period. Average ED admission rate during the Circuit Breaker period (48.3%) was higher as compared to pre-Circuit Breaker period (40.7%), however average daily admission remained stable. Conclusion: The COVID-19 pandemic caused a reduction in SGH ED attendances amongst patients with low-acuity conditions and those with highest priority for emergency care. This raises concern about treatment-seeking delays and possible impact on health outcomes. Our data provides insights that may be useful for ED crowd management planning in the post-COVID-19 era. There should be cautious use of ED admission rate as a metric in evaluating ED performance during an outbreak.
Effect of Sweetener, Stabilizer, and Storage Temperature on Ice Recrystallization in Ice Cream (1996)

In ice cream manufacturing, control of ice crystal growth through proper formulation and storage temperature is important for stability during storage. The objective of this study was to investigate the influence of sweetener (sucrose, 20 dextrose equivalent corn syrup, 42 dextrose equivalent corn syrup, and 42 high fructose corn syrup), with and without stabilizer, on ice recrystallization in ice cream a t three storage temperatures. The relationship between thermal and physical properties and ice recrystallization rate was also studied.
Studies on the Usefulness of Saliva for Detection of Antibodies to HIV-1 (1993)

It has been reported that antibodies to HIV-1 could be detected in saliva of patients with AIDS. We studied whether saliva is potentially useful for screening of HIV-1 infected persons. Pairs of serum and saliva were collected from both 19 HIV-1 seropositive outpatients (CDC type, II:15, III:1, IV:3) of AIDS clinic in our hospital and 4 controls. Multiple saliva collection was done from seropositives periodically for 8 months after the first sampling. Serum and saliva were tested with ELISA and Western blot (WB) methods by using kits of diagnostics Pasteur (ELAVIA MIXT and LAV Blot-1). All pairs of serum and saliva from controls were clearly negative by ELISA. Nineteen sera of proven seropositive cases and paired 18 saliva samples were confirmed to be positive in ELISA test employed, but O.D. value of 1 saliva sample was below the cut-off level. However, in the follow-up study, samples taken from the same individuals after the first sampling showed positive results. Forty-seven saliva samples from seropositives were served for the WB test. Clearly positive bands were observed in 43 samples. In each of the remaining 5 samples, the final decision was "indeterminate", although a strong reactive band was observed at GP-160. The results mentioned above suggested that saliva was useful for screening of antibodies to HIV-1 in epidemiological studies, though it is necessary to improve the sensitivity of ELISA and WB for tests of saliva.
Recommendations for isolation monitor ground fault detectors on residential and utility-scale PV systems (2015)

PV faults have caused rooftop fires in the U.S., Europe, and elsewhere in the world. One prominent cause of past electrical fires was the ground fault detection “blind spot” in fuse-based protection systems uncovered by the Solar America Board for Codes and Standards (SolarABCs) steering committee in 2011. Fortunately, a number of alternatives to ground fault fuses have been identified, but there has been limited adoption and historical use of these technologies in the United States. This paper investigates the efficacy of one of these devices known as isolation monitoring (or isolation resistance monitoring, Riso) in small (∼3kW) and large (∼700 kW) arrays. Unfaulted and faulted PV arrays were monitored with Riso technology and compared to SPICE simulations to recommend appropriate thresholds to the maximize the range of ground faults which could be detected while minimizing unwanted tripping. Based on analytical and computational models, it is impossible to determine a trip threshold that provides fire safety and negates unwanted tripping issues. This paper mathematically demonstrates that appropriate Riso trip thresholds must be determined on an arrayby- array basis with sufficient leeway by system operators to adjust trip threshold settings for their particular usage cases.
Editorial Comment (1988)

No AccessJournal of Urology1 Oct 1988Editorial Comment Joseph W. Segura Joseph W. SeguraJoseph W. Segura More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)57799-XAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Editorial Comment." The Journal of Urology, 140(4), p. 792 © 1988 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 140Issue 4October 1988Page: 792 Advertisement Copyright & Permissions© 1988 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Joseph W. Segura More articles by this author Expand All Advertisement PDF downloadLoading ...
Si-Photonic Waveguide Grating Coupler Arrays for Wavefront Monitoring (2022)

A silicon photonic wavefront monitoring chip may be designed using arrays of surface grating couplers. Such a chip can monitor wavefront distortion across a pupil plane in adaptive optics systems for free space optical communications and astronomy. This paper reports experimental results for grating pair wavefront monitor elements intended as building blocks for such an array. Wavefront tilt signals of 6 dB/degree and 10 dB/degree, respectively, are measured for grating pairs arranged in power ratio and interferometric configurations.
Tempering Optimism Concerning the Recent Decline in US Suicide Deaths (2022)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Psychiatry HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Psychiatry journal
Dilute Acid Pretreatment, Enzymatic Saccharification, and Fermentation of Rice Hulls to Ethanol (2005)

Rice hulls, a complex lignocellulosic material with high lignin (15.38 +/- 0.2%) and ash (18.71 +/- 0.01%) content, contain 35.62 +/- 0.12% cellulose and 11.96 +/- 0.73% hemicellulose and has the potential to serve as a low-cost feedstock for production of ethanol. Dilute H2SO4 pretreatments at varied temperature (120-190 degrees C) and enzymatic saccharification (45 degrees C, pH 5.0) were evaluated for conversion of rice hull cellulose and hemicellulose to monomeric sugars. The maximum yield of monomeric sugars from rice hulls (15%, w/v) by dilute H2SO4 (1.0%, v/v) pretreatment and enzymatic saccharification (45 degrees C, pH 5.0, 72 h) using cellulase, beta-glucosidase, xylanase, esterase, and Tween 20 was 287 +/- 3 mg/g (60% yield based on total carbohydrate content). Under this condition, no furfural and hydroxymethyl furfural were produced. The yield of ethanol per L by the mixed sugar utilizing recombinant Escherichia colistrain FBR 5 from rice hull hydrolyzate containing 43.6 +/- 3.0 g fermentable sugars (glucose, 18.2 +/- 1.4 g; xylose, 21.4 +/- 1.1 g; arabinose, 2.4 +/- 0.3 g; galactose, 1.6 +/- 0.2 g) was 18.7 +/- 0.6 g (0.43 +/- 0.02 g/g sugars obtained; 0.13 +/- 0.01 g/g rice hulls) at pH 6.5 and 35 degrees C. Detoxification of the acid- and enzyme-treated rice hull hydrolyzate by overliming (pH 10.5, 90 degrees C, 30 min) reduced the time required for maximum ethanol production (17 +/- 0.2 g from 42.0 +/- 0.7 g sugars per L) by the E. coli strain from 64 to 39 h in the case of separate hydrolysis and fermentation and increased the maximum ethanol yield (per L) from 7.1 +/- 2.3 g in 140 h to 9.1 +/- 0.7 g in 112 h in the case of simultaneous saccharification and fermentation.
Fibre‐optic biosensor based on luminescence and immobilized enzymes: Microdetermination of sorbitol, ethanol and oxaloacetate (1990)

We have investigated highly selective and ultrasensitive biosensors based on luminescent enzyme systems linked to optical transducers. A fibre-optic sensor with immobilized enzymes was designed; the solid-phase bioreagent was maintained in close contact contact with the tip of a glass fibre bundle connected to the photomultiplier tube of a luminometer. A bacterial luminescence fibre-optic sensor was used for the microdetermination of NADH. Various NAD(P)-dependent enzymes, sorbitol dehydrogenase, alcohol dehydrogenase and malate dehydrogenase, were co-immobilized on preactivated polyamide membranes with the bacterial system and used for the microdetermination of sorbitol, ethanol and oxaloacetate at the nanomolar level with a good precision.
Chemical Imaging of the Spatial Distribution and Interactions of Tannin Dispersal in Bioplastic Systems (2007)

IR chemical imaging has been used to characterise the dispersion of condensed tannin additives in a biodegradable plastic, poly(butylene succinate). By mapping key FTIR absorptions, acetylated tannin was found to remain in discrete aggregates, though the outer of these particles contained a mixed phase with PBS. In particles &gt;100 μm, PBS does not appear to ingress the tannin core, only wetting the outer region. Analysis of a second tannin derivative indicated that there was a more uniform dispersion of the additive in the PBS matrix.
Oxidative Esterification of Methacrolein to Methyl Methacrylate over Gold Nanoparticles on Hydroxyapatite (2017)

Abstract The catalytic production of methyl methacrylate through the direct oxidative esterification of methacrolein is important in terms of green chemistry and sustainable development. In the present work, Au nanoparticles supported on three needle‐like, lamella‐like, and rodlike hydroxyapatites were synthesized. We demonstrated that needle‐like hydroxyapatite could facilitate the higher dispersion of Au species because of its high specific surface area, and the strong interaction between the Au nanoparticles and the support resulted in the formation of more surface defects because of the existence of partially encapsulated Au particles by the needle‐like hydroxyapatite. The surface defects were related closely to the generation of strong basic sites. Compared with the other two materials, the Au supported on the needle‐like hydroxyapatite catalyst, which had a large amount of surface acid–base sites, exhibited a much higher catalytic activity and selectivity to methyl methacrylate in the direct oxidative esterification of methacrolein with methanol under mild reaction conditions (i.e., ambient pressure, low reaction temperature of 70 °C, and low methanol/aldehyde ratio of 8:1). The superior catalytic performance of the Au supported on needle‐like hydroxyapatite catalyst was attributable to a cooperative effect between abundant acid–base sites for the preferential chemisorption of methacrolein and highly dispersed active Au species for the favorable formation of β‐hydride and oxygen activation. The present findings open a new and promising route for the practical production of methyl methacrylate using high‐performance hydroxyapatite‐supported metal catalyst systems.
Wall and Support Interference Corrections of NASA Common Research Model Wind Tunnel Tests in JAXA (2013)

In the JAXA 2m x 2m Transonic Wind Tunnel (JTWT), there have been more needs of wind tunnel users for high measurement accuracy to develop aircraft and launch vehicles with high performance. Integration modern test techniques of the JTWT have to be established. Wind tunnel tests with an 80% scaled NASA Common Research Model (CRM) are conducted to validate our results. Errors of balance output due to balance calibration temperature are confirmed. The test section Mach number, the clear tunnel buoyancy, the wall interference, and the upflow angle corrections are integrated and applied to the CRM wind tunnel tests data in the JTWT. Support interference effects with results of CFD with support and CFD without support are investigated. Moreover, our wall interference correction results and support interference effects are compared with wall interference corrections of the NASA National Transonic Facility (NTF) and the NASA Ames 11-ft Wind Tunnel, and support interference effects of the NTF. Thus, these results show that aerodynamic data, which are not affected by wind tunnel, can be estimated more precisely by the application of the balance calibration matrix, fundamental wind tunnel interference corrections, and the support interference correction appropriately.
Biomechanical markers and theoretical concepts related to haemophilic ankle and subtalar joint arthropathy: introducing the term ‘haemophilic tarsal pan‐arthropathy’ (2017)

In this context, the authors propose the use of 'haemophilic tarsal pan-arthropathy' (HTPA) which encompasses both tibiotalar and subtalar joints.
Self-developing resist with submicrometer resolution and processing stability (1983)

Nitrocellulose films have been shown to function as self-developing resist layers that are sensitive to both low-energy (&amp;lt;2 keV) Ar+ ions and to 193-nm UV radiation from pulsed excimer lasers. A resolution of &amp;lt;100 nm and aspect ratios &amp;gt;25:1 have been demonstrated using a stencil mask and an argon ion beam; the resolution obtained was mask limited. The sensitivity of the resist to 2-keV Ar+ ions is 36 μm/min at beam currents of 1 mA/cm2, allowing exposure times of 1 s for 0.5 μm of resist. The material is capable of functioning as a mask material for typical semiconductor dry etching processes.
Broadcast Approach for the Information Bottleneck Channel (2020)

This work considers a layered coding approach for efficient transmission of data over a wireless block fading channel without transmitter channel state information (CSI), which is connected to a limited capacity reliable link, known as the bottleneck channel. Two main approaches are considered, the first is an oblivious approach, where the sampled noisy observations are compressed and transmitted over the bottleneck channel without having any knowledge of the original information codebook. The second approach is a non-oblivious decode-forward (DF) relay where the sampled noisy data is decoded, and whatever is successfully decoded is reliably transmitted over the bottleneck channel. The bottleneck channel from relay to destination has a fixed capacity C. We examine also the case where the channel capacity can dynamically change due to variable loads on the backhaul link. The broadcast approach is analyzed for cases that only the relay knows the available capacity for next block, and for the case that neither source nor relay know the capacity per block, only its capacity distribution. Fortunately, it is possible to analytically describe in closed form expressions, the optimal continuous layering power distribution which maximizes the average achievable rate. Numerical results demonstrate the achievable broadcast rates.
Risk Factors for Venous Thromboembolism (2003)

Until the 1990s, venous thromboembolism (VTE) was viewed primarily as a complication of hospitalization for major surgery (or associated with the late stage of terminal illness). However, recent trials in patients hospitalized with a wide variety of acute medical illnesses have demonstrated a risk of VTE in medical patients comparable with that seen after major general surgery. In addition, epidemiologic studies have shown that between one quarter and one half of all clinically recognized symptomatic VTEs occur in individuals who are neither hospitalized nor recovering from a major illness. This expanding understanding of the population at risk challenges physicians to carefully examine risk factors for VTE to identify high-risk patients who could benefit from prophylaxis. Factors sufficient by themselves to prompt physicians to consider VTE prophylaxis include major surgery, multiple trauma, hip fracture, or lower extremity paralysis because of spinal cord injury. Additional risk factors, such as previous VTE, increasing age, cardiac or respiratory failure, prolonged immobility, presence of central venous lines, estrogens, and a wide variety of inherited and acquired hematological conditions contribute to an increased risk for VTE. These predisposing factors are seldom sufficient by themselves to justify the use of prophylaxis. Nevertheless, individual risk factors, or combinations thereof, can have important implications for the type and duration of appropriate prophylaxis and should be carefully reviewed to assess the overall risk of VTE in each patient.