gebhart/patrepeval huggingface dataset:
UML extensions for real-time control systems (2004)

The use of object oriented techniques and methodologies for the design of real-time control systems appear to be necessary in order to deal with the increasing complexity of such systems. Many object-oriented methods have been used for the modeling and design of real-time control systems. We believe that an approach that integrates the advancements in both object modeling and design methods, and real-time scheduling theory is the key to successful use of object oriented technology for real-time software. Surprisingly several past approaches to integrate the two either restrict the object models, or do not allow sophisticated schedulability analysis techniques. In this paper we show how schedulability analysis can be integrated with object-oriented design. More specifically, we develop the schedulability and feasibility analysis method for the external messages that may suffer release jitter due to being dispatched by a tick driven scheduler in real-time control system, and we also develop the schedulability method for sporadic activities, where message arrive sporadically then execute periodically for some bounded time. This method can be used to cope with timing constraints in realistic and complex real-time control systems. Using this method, a designer can quickly evaluate the impact of various implementation decisions on schedulability. In conjunction with automatic code-generation, we believe that this greatly streamlines the design and development of real-time control system software.
Deterministic Modeling of Degenerative RAFT Miniemulsion Polymerization Rate and Average Polymer Characteristics: Invalidity of Zero–One Nature at Higher Monomer Conversions (2018)

The polymerization rate and average polymer characteristics of degenerative reversible addition–fragmentation chain transfer (RAFT) miniemulsion polymerization of methyl methacrylate with cyanoprop-2-yl dithiobenzoate as initial RAFT agent (R0X) and potassium persulfate as initiator are studied at 333 K up to monomer conversions of 95%, considering a two-dimensional Smith–Ewart model. This model accounts for the number of macroradicals and R0 radicals per nanoparticle, an average particle size between 50 and 500 nm, targeted chain lengths (TCLs) between 50 and 600, exit/entry of R0 radicals, and the possible influence of diffusional limitations on termination and RAFT transfer at the microscale. The accuracy of the microscale model parameters is highlighted by a successful description of bulk literature data, and the interphase mesoscale parameters are determined based on literature miniemulsion data at various average particle sizes. It is demonstrated that at high monomer conversions it is not afforded to assume zero–one kinetics due to diffusional limitations on termination. With larger average chain lengths this deviation is more pronounced and further accelerated by diffusional limitation on RAFT transfer. Even though the miniemulsion kinetics are faster than the bulk counterpart, retardation due to consecutive entry/exit events of R0 radicals can be observed as long as R0X is present.
Efficiency modeling in voltage source inverters with several PWM techniques: A unified approach (2013)

In this paper several PWM techniques have been studied and a unified approach allowing their implementation by using a general expression of the duty cycle is proposed. These techniques are experimentally investigated to evaluate their impact on power losses and efficiency in a VSI for AC variable speed drives. In particular, both continuous and discontinuous PWM methods have been addressed and experimentally tested. Moreover a power losses dynamic model for the VSI is developed and validated on the basis of experimental tests.
From cholera to corals: Viruses as drivers of virulence in a major coral bacterial pathogen (2015)

Disease is an increasing threat to reef-building corals. One of the few identified pathogens of coral disease is the bacterium Vibrio coralliilyticus. In Vibrio cholerae, infection by a bacterial virus (bacteriophage) results in the conversion of non-pathogenic strains to pathogenic strains and this can lead to cholera pandemics. Pathogenicity islands encoded in the V. cholerae genome play an important role in pathogenesis. Here we analyse five whole genome sequences of V. coralliilyticus to examine whether virulence is similarly driven by horizontally acquired elements. We demonstrate that bacteriophage genomes encoding toxin genes with homology to those found in pathogenic V. cholerae are integrated in V. coralliilyticus genomes. Virulence factors located on chromosomal pathogenicity islands also exist in some strains of V. coralliilyticus. The presence of these genetic signatures indicates virulence in V. coralliilyticus is driven by prophages and other horizontally acquired elements. Screening for pathogens of coral disease should target conserved regions in these elements.
Superconducting stripline resonator performance (1989)

Reliable techniques for evaluating the microwave properties of superconductors are essential in providing calibrated data for exchange between laboratories and for developing practical device designs. The authors are examining the techniques which utilize microwave stripline resonators. These resonators provide for the rapid measurement of microwave parameters in a repeatable fashion with minimal constraints on processing. Sandwiched microstrip line resonators are used to compare the performance at 4.2 K of OFHC copper and superconducting films of Pb, Nb, and YBa/sub 2/Cu/sub 3/O/sub 7/ (YBCO) at C-band and X-band. Typical results for the Nb resonators show a loaded Q/sub L/ of about 8*10/sup 4/ with a transmission insertion loss of 5 dB at 3 GHz. Initial results on a YBCO a-axis film used as a ground plane in the Nb resonator yield a surface resistance value of about 10/sup -3/ Omega at 2.8 GHz. Preliminary results on the phase noise performance of a Nb resonator at 2.9 GHz are presented.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Local hyperthermia and radiation therapy in the treatment of superficially located lymphomas and recurrent Hodgkin's disease (1996)

The combination of radiation therapy CRT) and hyperthermia (HT) has proved to be an effective treatment of a wide variety of superficially located recurrences of different tumors, particularly those arising in previously irradiated areas. Some studies have been reported with the use of this combined approach in the management of cutaneous lymphomas or recurrent previously irradiated sites of Hodgkin's disease (HD). We report a small series of five patients with six located sites of recurrent HD, and four patients with six superficially located sites of non Hodgkin's lymphomas (NHL), all of them being treated with combined HT and RT at our institution. Local control was obtained in each of combined treatment fields, and all patients are alive after a median follow-up of 24 months. All the patients tolerated the HT treatments well, and in all cases average intratumoral temperatures were >42 degrees C, with 8 out of 12 sites achieving the goal of average temperatures >42.5 degrees C. Two patients, one with recurrent HD and one with NHL, are free of disease after 20 and 21 months from the end of combined therapy. Our results thus seem to confirm previous experiences, suggesting a role of HT/RT not only for palliative purposes in cutaneous lymphomas, but also in the management of selected, heavily pretreated patients with superficially located recurrences of HD.
Ammonia Decomposition over Iron Phthalocyanine‐Based Materials (2015)

Abstract Iron phthalocyanine‐based materials have been used herein as efficient catalysts for the ammonia decomposition reaction. These materials showed high activity, even superior to that showed by the commercial nickel‐based catalyst and iron‐doped carbon nanotubes, which were used as benchmarks in this study. Catalyst stability under reaction conditions appeared satisfactory, because no deactivation phenomena were observed. The type of the phthalocyanine precursor did not affect the catalytic performance; however, the preparation method had a strong effect. If the resulting material was exposed to the reaction conditions, some structural modification occurred. No clear correlation between phase composition and activity could be established because similar nitrogen content and similar crystalline domains in the sample led to different behaviors. However, the results of extensive characterization suggested that catalytic activities and conversion profiles were most likely dependent on material textural properties and thus on the preparation method used. The accessibility of iron species seems to be limited for catalysts prepared under vacuum. These phenomena are most likely responsible for the activation profile and for the low catalytic activity typical of these materials. In contrast, higher accessibility of iron species, typical of materials prepared under argon, would lead to improved and stable catalytic performance.
Candidate Gene Analysis of Arteriovenous Fistula Failure in Hemodialysis Patients (2013)

In this large cohort of hemodialysis patients, only 2 of the 43 candidate SNPs were associated with an increased risk of AVF failure. Whether other factors, like local hemodynamic circumstances, are more important or other SNPs play a role in AVF failure remains to be elucidated.
High-Dose Glycine Treatment of Refractory Obsessive-Compulsive Disorder and Body Dysmorphic Disorder in a 5-Year Period (2009)

This paper describes an individual who was diagnosed with obsessive-compulsive disorder (OCD) and body dysmorphic disorder (BDD) at age 17 when education was discontinued. By age 19, he was housebound without social contacts except for parents. Adequate trials of three selective serotonin reuptake inhibitors, two with atypical neuroleptics, were ineffective. Major exacerbations following ear infections involving Group A beta-hemolytic streptococcus at ages 19 and 20 led to intravenous immune globulin therapy, which was also ineffective. At age 22, another severe exacerbation followed antibiotic treatment for H. pylori. This led to a hypothesis that postulates deficient signal transduction by the N-methyl-D-aspartate receptor (NMDAR). Treatment with glycine, an NMDAR coagonist, over 5 years led to robust reduction of OCD/BDD signs and symptoms except for partial relapses during treatment cessation. Education and social life were resumed and evidence suggests improved cognition. Our findings motivate further study of glycine treatment of OCD and BDD.
Three-Dimensional Simulation of Blood Flow in an Abdominal Aortic Aneurysm—Steady and Unsteady Flow Cases (1994)

Atherosclerosis and atherosclerotic aneurysms can occur in the abdominal aorta. Steady and unsteady three-dimensional flow cases were simulated in abdominal aortic aneurysm using a flow simulation package on a graphics workstation. In the steady case, three aneurysm models of 8.0 cm length were simulated using Reynolds numbers of 350 and 700. In the unsteady case, blood flow in a single asymmetric aneurysm of 8.0 cm length was simulated at Reynolds numbers of 350 and 700 and 1400. In the aneurysm center, two symmetric vortices were formed, and flow separation started at the aneurysm inlet. In the unsteady flow case, the main vortex appeared and disappeared and changed position in the unsteady flow case and induced vortices were formed. Although the centerline view shows the vortices change position with time, cross-sectional views show that two symmetric vortices are present or partially formed throughout the entire flow cycle. Regions of high pressure were observed at the aneurysm exit caused by the symmetric vortices that were formed, implying that this high-pressure region could be an area where rupture is most likely. In the unsteady case, regions of maximum pressure moved depending on the flow cycle time; at peak flow, local pressure maximums were observed at the distal aneurysm; these oscillated, tending to put an additional strain on the distal portion of the aneurysm. The shear stress was low in the aneurysm portion of the vessel, and local maximum values were observed at the distal aneurysm constriction.
Nature Versus Nurture in Cardiac Conduction (2008)

Information about reprints can be found online at: Reprints: document. Permissions and Rights Question and Answer about this process is available in the located, click Request Permissions in the middle column of the Web page under Services. Further information Editorial Office. Once the online version of the published article for which permission is being requested is can be obtained via RightsLink, a service of the Copyright Clearance Center, not theCirculation Researchin Requests for permissions to reproduce figures, tables, or portions of articles originally publishedPermissions: by guest on March 4,
Imaging conformations of holo- and apo-transferrin on the single-molecule level by low-energy electron holography (2023)

Conformational changes play a key role in the biological function of many proteins, thereby sustaining a multitude of processes essential to life. Thus, the imaging of the conformational space of proteins exhibiting such conformational changes is of great interest. Low-energy electron holography (LEEH) in combination with native electrospray ion beam deposition (ES-IBD) has recently been demonstrated to be capable of exploring the conformational space of conformationally highly variable proteins on the single-molecule level. While the previously studied conformations were induced by changes in environment, it is of relevance to assess the performance of this imaging method when applied to protein conformations inherently tied to a function-related conformational change. We show that LEEH imaging can distinguish different conformations of transferrin, the major iron transport protein in many organisms, by resolving a nanometer-scale cleft in the structure of the iron-free molecule (apo-transferrin) resulting from the conformational change associated with the iron binding/release process. This, along with a statistical analysis of the data, which evidences a degree of flexibility of the molecules, indicates that LEEH is a viable technique for imaging function-related conformational changes in individual proteins.
Quantification of Nucleation Site Density as a Function of Surface Wettability on Smooth Surfaces (2022)

Abstract Dew water is recognized as a valuable source of clean water for human consumption. Given the developing concerns over global water scarcity, great focus has been turned toward increasing the efficiency of existing dew harvesting methodologies. Droplet nucleation is a critical first stage in the condensation process – and therefore key to dew water harvesting. In this paper, the droplet nucleation site density ( N s ) as a function of surface wettability on smooth thin polymer films is quantified. A custom‐built environment chamber, operated in low supersaturation conditions relevant to atmospheric water harvesting, allows strict experimental control over temperature and humidity. Droplet growth through coalescence is quantified, and an exponential increase in the rate of coalescence is seen as the test surface wettability increased. N s declines exponentially as wettability decreases according to the fitted equation N s = 1.1 × 10 11 e −0.043θ , where theta is the contact angle of the smooth surface, which can be used to predict N s from a known contact angle, currently not available. The average distance between droplet centers is found to increase at a linear rate. This nucleation behavior is in line with those of droplets in a Rayleigh distribution.
Are WHO Recommendations to Perform 2 Consecutive Semen Analyses for Reliable Diagnosis of Male Infertility Still Valid? (2018)

In accordance with WHO recommendations 2 consecutive semen analysis should be performed.
Characterization of asymmetrical half bridge flyback converter (2003)

Flyback derived converters are attractive because of their simple capacitive output filter when compared with other converters used in multiple-output or cost-sensitive applications. This paper analyzes the detailed circuit behavior of the asymmetrical half bridge flyback converter. Several practical issues, including the specific relationships between the duty cycle and the different types of energy in the energy-storage elements, and the zero voltage switching (ZVS) conditions of the power switches have been thoroughly examined. Mathematical equations have also been given. A 5 V/20 A prototype has been built to verify the analytical results.
Control of light in the non-adiabatic regime in integrated optical waveguides (2023)

We demonstrate that coupled waveguides systems can be operated in the so called non-adiabatic regime. In this regime, light can undergo transition between different steady states, also called photonic bands. This approach contrasts with previous strategies in integrated photonics that rely exclusively on the adiabatic control of the flow of light. We show that the constraint for adiabaticity being lifted, light can now be manipulated optimally.
Built-in Clock Domain Crossing (CDC) test and diagnosis in GALS systems (2010)

The purpose of this paper is to present a novel built-in Clock Domain Crossing (CDC) test and diagnosis methodology for Globally Asynchronous, Locally Synchronous (GALS) systems. The methodology allows design and prototype validation, low maintenance and repair costs, and production / lifetime at-speed test. Moreover, high resolution diagnosis is obtained, to identify which device(s) and/or communication channel(s) is (are) faulty. This is not trivial in GALS systems, for which the CDC issue is challenging. The underlying principle of the proposed methodology is to embed a CDC test and diagnosis (CDC T&D) structure in each locally synchronous domain. Complete device-to-device communication channels are tested, including transceivers, buses, and board connectors. Identical test patterns (generated to detect static (stuck-at, shorts and open faults) and dynamic (crosstalk) faults) are used in each FPGA. The proposed CDC T&D methodology is validated in a case study, the acquisition electronics of a complex multi-board, multibus, multi-FPGA (nine Xilinx™ xc2v4000-4bf957) system. Test and validation results are presented.
Application Of Long Range Holography In Earthquake Engineering (1990)

Holography concepts have been evaluated as nonintrusive tools that can measure earthquake effects and earthquake resistance of structures. The methods offer potential for removing limitations currently obstructing the application of advanced design techniques in civil and earthquake engineering. Methods under study can result in a capability to holographically monitor large, distant surfaces such as the face of a building, bridge foundation, liquid storage tank, or dam during interaction with geological or meteorological forces. This work included the successful demonstration that holography could be used to obtain modal information from a 3.4-meter-tall, liquid storage tank at a distance of 20 meters.
Identification of a novel protein encoded by the BamHI A region of the Epstein-Barr virus (1997)

An unusual set of 3' coterminal, spliced mRNAs transcribed through the BamHI A fragment have been previously identified in nasopharyngeal carcinoma (NPC) tissues. These RNAs have also been detected at low levels in Burkitt's lymphoma (BL) cell lines and Epstein-Barr virus (EBV)-transformed lymphocytes. Sequence analyses of clones from a cDNA library derived from the C15 NPC tumor indicated that the primary transcripts are differentially spliced, giving rise to a family of related transcripts, all of which encompass the BARF0 open reading frame (ORF) at the 3' end of the transcripts. One cDNA was identified that extended the BARF0 ORF at the 5' end, forming the RK-BARF0 ORF. In this study, a rabbit antiserum to a synthetic peptide representing an amino acid sequence encoded by the BARF0 ORF was prepared. This antiserum detected a glutathione S-transferase-BARF0 fusion protein and both BARF0 and RK-BARF0 proteins expressed from transfected constructs in H1299 cells. The serum also immunoprecipitated the 20-kDa BARF0 and 30-kDa RK-BARF0 in vitro-translated proteins. Immunoblot analyses identified a protein doublet of 30 and 35 kDa in all of the EBV-infected cell lines tested. Cellular fractionation studies revealed that the proteins were membrane associated. The sizes of the proteins detected in cell lines and their association with membranes suggests that they are likely encoded by the RK-BARF0 transcript, which is predicted to contain a membrane localization signal. The proteins were also detected in protein extracts prepared from NPC biopsies and a BL biopsy but not from hairy leukoplakia, a permissive EBV infection. These results reveal that the rightward RNA transcripts from the BamHI A region of EBV encode one or more proteins that are expressed in latently infected cells and in tumor tissue.
Othello Error: Facial Profiling, Privacy, and the Suppression of Dissent (2007)

In this article, Professor Herbert challenges the US. Transportation Security Administration's post-September 11, 2001, use of Paul Elanan and Wallace Friesen's Facial Action Coding System (FACS) to identify potential terrorists in American airports. Professor Herbert asserts that invasive visual examination of travelers' faces and facial expressions for law enforcement purposes under the auspices of protective administrative searches ineffectively protects national and airport security and violates reasonable expectations of privacy. FACS improperly provides unreasonable governmental activity with a legitimizing scientific imprimatur that conceals governmental agents' race- and ethnicity-based prejudices, which leads to targeting minorities' faces as portents of danger. Professor Herbert assesses the concept of facial privacy in public, and in doing so, rejects the Supreme Court's Katz v. United States test and argues in support of constitutional protection of public privacy.
Supplementary Figure 1 from Microenvironmental Regulation of <i>BRCA1</i> Gene Expression by c-Jun and Fra2 in Premalignant Human Ovarian Surface Epithelial Cells (2023)

&lt;p&gt;PDF file - 525K, A dominant-negative AP1 effector decreases BRCA1 promoter activity in monolayer culture.&lt;/p&gt;
Effect of Processing, Packaging and Vibration Treatment on the Sensory Quality of Fresh‐cut Apple Slices (2011)

SUMMARY Fresh‐cut fruit industry has seen tremendous growth in recent years. The present study was designed with the objective of studying the sensory quality of fresh‐cut apple slices that were treated with different antibrowning agents, packed in three types of packaging materials and subjected to vibration treatment to simulate commercial transportation. The slices were treated with two commercial antibrowning agents [NatureSeal (Mantrose‐Haeuser Co., Inc., Westport, CT, USA) and Ever‐Fresh (Kraft Foods, Inc., Rye Brook, NY, USA)] at 5% (w/v) application rate. The treated slices were packaged in 5 oz polystyrene rigid container, 2 lb polyethylene bag or 2 oz polyethylene bag. A nine‐member trained panel and a 100‐member consumer panel evaluated the treated slices for selected sensory attributes. The trained sensory small panel found minimal difference in the fresh‐cut slices in comparison with the control (non‐vibrated) sample, with the slices treated with NatureSeal better in quality than those treated with Ever‐Fresh. Case positions (bottom, middle or top) within the vibration stack did not affect the quality of the slices significantly; similar results were found from the consumer panel sensory evaluation. The consumer panel evaluation results showed that the slices treated with NatureSeal were better in sensory attributes of colour, texture, flavour and overall acceptability. Overall, package type had no or minimal effect on the slice quality attributes. Copyright © 2011 John Wiley &amp; Sons, Ltd.