gebhart/patrepeval huggingface dataset:
Ionic memories: Status and challenges (2008)

Ionic memory is a type of resistive switching memories based on ionic transport and electrochemical reactions in solid-state electrolyte materials. In cation-migration-based ionic memories, cations transport through solid electrolyte under electric field and deposit as metal atoms to form connecting bridge between two electrodes. With repeatable resistance change over several orders of magnitude and long retention, ionic memory is a promising candidate for next generation non-volatile memories. The advantages of ionic memories include low operation voltage and highly scalable device size. As two-terminal devices with hysteretic resistive behavior, ionic memories may enable novel architectures and algorithms. The major challenge for ionic memories exists in operation reliability. This paper will review the R&D status of ionic memory technology and discuss the challenges.
Analog to digital and digital to analog conversion based on stochastic logic (2002)

Digital to analog and analog to digital conversions can be realized in VLSI integrated circuits using a strictly digital technology and some additional analog circuits outside the IC. These techniques are based on the generation of a pulse sequence that represents a digital number. The mean value of this pulse sequence is obtained at the output of a low-pass external filter. The authors propose the use a stochastic pulse sequence instead of a traditional PWM signal. This technique has important advantages. Stochastic pulse sequences can be mathematically processed by extremely simple circuits. The product and addition of stochastic pulses can be evaluated by AND gates. The spectral properties of stochastic pulse sequences lead to less restrictive conditions to be imposed to the filter that makes the analog conversion of the pulse sequence. The authors have used this technique to implement digital to analog and analog to digital conversion in an integrated circuit that is currently being designed for a Spanish company.
Phosphorylation of the AfsR product, a global regulatory protein for secondary-metabolite formation in Streptomyces coelicolor A3(2) (1991)

The AfsR protein is essential for the biosynthesis at the wild-type level of A-factor, actinorhodin, and undecylprodigiosin in Streptomyces coelicolor A3(2) and Streptomyces lividans. Because overexpression of the afsR gene caused some deleterious effect on these strains, a multicopy plasmid carrying the whole afsR gene was introduced into Streptomyces griseus, from which a crude cell lysate was prepared as a protein source. The AfsR protein was purified to homogeneity from the cytoplasmic fraction through several steps of chromatography, including affinity column chromatography with ATP-agarose and use of anti-AfsR antibody for its detection. The molecular weight of AfsR was estimated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and by gel filtration to be 105,300, which is in good agreement with that deduced from the nucleotide sequence of afsR. The purified AfsR protein was found to be phosphorylated through the transfer of the gamma-phosphate group of ATP in the presence of the cell extracts of S. coelicolor A3(2) and S. lividans. This phosphorylation proceeded very rapidly, and no competition was observed with CTP, GTP, UTP, or cyclic AMP. In the cell extract of S. griseus, no activity phosphorylating the AfsR protein was detected, suggesting that this activity is not generally present in Streptomyces spp. but is specific to certain species. It is conceivable that the extent of phosphorylation of the AfsR protein modulates its regulatory activity which, in turn, regulates expression of some target gene(s) involved in the secondary-metabolite formation in S. coelicolor A3(2).
Incorporating User’s Preference into Attributed Graph Clustering : Extended abstract (2023)

In contrast to global graph clustering, local graph clustering aims to find only one cluster that is concentrating on the given seed vertex (and also on the designated attributes for attributed graphs). Currently, very few methods can deal with this kind of task. To this end, we propose two quality measures for a local graph cluster: Graph Unimodality (GU) and Attribute Unimodality (AU). They measure the homogeneity/unimodality of the graph structure and the subspace that is composed of the designated attributes, respectively. We call their linear combination Compactness. Further, we propose LOCLU to optimize the Compactness score in order to find a good local graph cluster. The local graph cluster detected by LOCLU concentrates on the region of interest, provides efficient information flow in the graph, and exhibits a unimodal data distribution in the subspace of the designated attributes.
Functional Characterization of Gne (UDP- N -Acetylglucosamine- 4-Epimerase), Wzz (Chain Length Determinant), and Wzy (O-Antigen Polymerase) of Yersinia enterocolitica Serotype O:8 (2002)

The lipopolysaccharide (LPS) O-antigen of Yersinia enterocolitica serotype O:8 is formed by branched pentasaccharide repeat units that contain N-acetylgalactosamine (GalNAc), L-fucose (Fuc), D-galactose (Gal), D-mannose (Man), and 6-deoxy-D-gulose (6d-Gul). Its biosynthesis requires at least enzymes for the synthesis of each nucleoside diphosphate-activated sugar precursor; five glycosyltransferases, one for each sugar residue; a flippase (Wzx); and an O-antigen polymerase (Wzy). As this LPS shows a characteristic preferred O-antigen chain length, the presence of a chain length determinant protein (Wzz) is also expected. By targeted mutagenesis, we identify within the O-antigen gene cluster the genes encoding Wzy and Wzz. We also present genetic and biochemical evidence showing that the gene previously called galE encodes a UDP-N-acetylglucosamine-4-epimerase (EC 5.1.3.7) required for the biosynthesis of the first sugar of the O-unit. Accordingly, the gene was renamed gne. Gne also has some UDP-glucose-4-epimerase (EC 5.1.3.2) activity, as it restores the core production of an Escherichia coli K-12 galE mutant. The three-dimensional structure of Gne was modeled based on the crystal structure of E. coli GalE. Detailed structural comparison of the active sites of Gne and GalE revealed that additional space is required to accommodate the N-acetyl group in Gne and that this space is occupied by two Tyr residues in GalE whereas the corresponding residues present in Gne are Leu136 and Cys297. The Gne Leu136Tyr and Cys297Tyr variants completely lost the UDP-N-acetylglucosamine-4-epimerase activity while retaining the ability to complement the LPS phenotype of the E. coli galE mutant. Finally, we report that Yersinia Wzx has relaxed specificity for the translocated oligosaccharide, contrary to Wzy, which is strictly specific for the O-unit to be polymerized.
A THEORY OF COAGULATION USEFUL FOR DESIGN (1962)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA THEORY OF COAGULATION USEFUL FOR DESIGNCharles P. PriesingCite this: Ind. Eng. Chem. 1962, 54, 8, 38–45Publication Date (Print):August 1, 1962Publication History Published online1 May 2002Published inissue 1 August 1962https://pubs.acs.org/doi/10.1021/ie50632a006https://doi.org/10.1021/ie50632a006research-articleACS PublicationsRequest reuse permissionsArticle Views313Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Repetitive transcranial magnetic stimulation (TMS) for medication-resistant depression. (2009)

The FDA has cleared a new device for treatment of major depressive disorder (MDD) resistant to antidepressant medication. The NeuroStar TMS System (Neuronetics) produces pulsed magnetic fields that can induce electrical currents in the brain. Unlike electroconvulsive therapy (ECT), it does not require anesthesia or induction of seizures. Other similar devices are under development.
Cell multiplication in metazoans: evidence for negative control of initiation in rat fibroblasts. (1981)

Experiments were performed to clarify the circumstances under which a rat fibroblast-like cell line proliferated in culture or when injected into syngeneic hosts. Rat FR3T3 and SV40FR3T3 cells in culture multiply exponentially at comparable rates regardless of the horse serum concentration in the culture medium. The concentration of horse serum in the medium determines the length of the exponential phase of cell multiplication. Heat inactivation of the serum for periods as long as 24 hr does not impair the ability of the serum to sustain maximal cell multiplication rates. At low serum concentrations the exponential phase may be prolonged by refeeding the cultures daily with fresh medium. In medium supplemented with 50% fresh rat serum, FRT3T3 and SV403T3 cells are prevented from multiplying by yet undefined component(s) in this serum. This correlates well with the lack of tumor formation by these cells when inoculated into syngeneic hosts. The evidence obtained in culture strongly suggests that the multiplication ability of established cells in culture is a dominant constitutive character of these cells that is expressed whenever they are provided with optimal supply of nutrients and when no specific inhibitory conditions are present. Based on the data presented, we postulate that cell multiplication is a repressible function. These data also are compatible with a negative control mechanism for cell multiplication.
Conservative Versus Arthroscopic Management for Medial Coronoid Process Disease in Dogs: A Prospective Gait Evaluation (2011)

AT dogs had increased mechanical asymmetry at 4 and 8 weeks compared to the CM group revealing surgery worsened limb function. There was no significant difference in mechanical symmetry between groups at 26 and 52 weeks.
Evaluation of distributed gas cooling of pressurized PAFC for utility power generation (1981)

Two short stacks were pressure tested at 446 kPa (4.4 atm.) and the pressure gains were more than the theoretically predicted gains. Temperature profiles were observed to be independent of operating pressure. The pressure drop was found to be inversely proportional to operating pressure as expected. Continuous pressurized operation of a stack for 1000 hours verified the compatability of the fuel cell component design. A simple pressurization procedure was also developed. Six separate designs, covering two gas cooling schemes (DIGAS and separated) and two cooling channel geometries (straight through and treed), were analysed on the net voltage output basis. Separated cooling with 5 cells per cooler was recognized to be the best among the designs considered.
CHEMICAL, CLINICAL, AND IMMUNOLOGICAL STUDIES ON THE PRODUCTS OF HUMAN PLASMA FRACTIONATION. XXXVII. THE METAL-COMBINING GLOBULIN OF HUMAN PLASMA 1 (1949)

The separation of the proteins of human plasma into a series of fractions and subtractions, uniform with respect to certain physical properties, has gen- erally led also to the separation of proteins with respect to their chemical and biological properties. Among the properties that have long been recog- nized has been the binding of metals by the plasma so that the metals were no longer freely dialyzable (1). When plasma fractionation was undertaken, early in the war, the Committee on Blood Substitutes of the National Research Council were informed that "investigations of the distribution of . . . metals known to be combined with proteins in the blood, such as copper, zinc, and iron, are planned and will be subsequently reported, as will studies upon the hormones and other physiologically important components of human plasma for which methods of bio-assay are available. We feel keenly that these should now be studied in the large amounts of human plasma fractions becom- ing available as by-products of the preparation of human albumin for transfusion in shock" (2).
PECVD Synthesis of Silicon Carbonitride Layers Using Methyltris(diethylamino)silane as the New Single-Source Precursor (2014)

Deposition of thin SiCxNy layers from a new single-source organosilicon compound, methyltris(diethylamino)silane (MTDEAS) mixed with helium or nitrogen is studied by using thermodynamic simulation of Si–C–N–H(He)–O system and experimentally by low pressure (10−2–10 Torr) plasma enhanced chemical vapor decomposition (PECVD) in the temperature range of 300–1300 K. Thermodynamic simulation allowed to find the temperature boundaries of solid phase formation. The phase composition, as well as physicochemical and functional properties of the layers has been studied using a complex of modern experimental techniques, including Raman spectroscopy, scanning electron (SEM) and atomic force microscopy (AFM), X-ray diffraction using synchrotron radiation (XRD-SR), ellipsometry and spectrophotometry. The electrophysical parameters were measured using the C-V characteristics. The microhardness and Young's modulus were determined by Nanoindentation method. It was shown that the layers contain crystals of phases belonging to Si3-xCxN4 structures, such as α-Si3N4, α-Si2CN4, α-SiC2N4, and α-C3N4 which, possibly, are embedded in the amorphous matrix of silicon carbonitride layers.
Custom Power Active Transformer for Flexible Operation of Power Systems (2017)

This paper presents a new transformer, i.e., the custom power active transformer (CPAT) which integrates both series and shunt power conditioning through power electronics into a single transformer. This is achieved through a distinct design of the magnetic circuit and auxiliary windings of the transformer. In this paper, a single-phase CPAT is proposed as well as a preface into its extension to multiphase systems. Through its magnetic equivalent circuit model, several design considerations and control limitations are revealed in the paper. Analysis of the resulting CPAT structure shows some prospects in material saving as well as size and cost reduction when compared to the traditional multitransformer-based configuration. In this paper, the proposed single-phase CPAT is utilized in a distribution system application, where the control architecture is designed to attenuate voltage and current distortions at both the load and the grid side, respectively. Performance and effectiveness of the proposed CPAT are evaluated through simulation and experiments.
Translocation of prepromelittin across the membrane of the endoplasmic reticulum (1993)

Conference Article| August 01 1993 Translocation of prepromelittin across the membrane of the endoplasmic reticulum S. Kulkarni; S. Kulkarni 1Dept of Surgery, St George's Hospital Medical School, Cranmer Terrace, LONDON SW17 ORE Search for other works by this author on: This Site PubMed Google Scholar M. He; M. He 1Dept of Surgery, St George's Hospital Medical School, Cranmer Terrace, LONDON SW17 ORE Search for other works by this author on: This Site PubMed Google Scholar B. M. Austen B. M. Austen 1Dept of Surgery, St George's Hospital Medical School, Cranmer Terrace, LONDON SW17 ORE Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1993) 21 (3): 311S. https://doi.org/10.1042/bst021311s Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Cite Icon Cite Get Permissions Citation S. Kulkarni, M. He, B. M. Austen; Translocation of prepromelittin across the membrane of the endoplasmic reticulum. Biochem Soc Trans 1 August 1993; 21 (3): 311S. doi: https://doi.org/10.1042/bst021311s Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1993 Biochemical Society1993 Article PDF first page preview Close Modal You do not currently have access to this content.
Design and fabrication of 1.5 μm ridge waveguide distributed feedback lasers (1985)

The paper describes the design and fabrication of distributed feedback lasers operating at around 1.5 μm, which utilise the ridge waveguide design for lateral mode and current confinement. The design considerations presented concentrate on the optimisation of waveguide layer compositions and thicknesses, together with the appropriate selection of diffraction-grating profile, in order to obtain strong grating coupling with the optical wave in the final device. We show that the devices made have operating characteristics comparable with the best DFB laser results so far reported. The high modulation capabilities afforded by the ridge waveguide structure are also demonstrated, and systems results show conclusively the high potential of these devices for future long-haul, high-bandwidth optical communication systems.
Label Refinement with an Iterative Generative Adversarial Network for Boosting Retinal Vessel Segmentation (2019)

State-of-the-art methods for retinal vessel segmentation mainly rely on manually labeled vessels as the ground truth for supervised training. The quality of manual labels plays an essential role in the segmentation accuracy, while in practice it could vary a lot and in turn could substantially mislead the training process and limit the segmentation accuracy. This paper aims to "purify" any comprehensive training set, which consists of data annotated by various observers, via refining low-quality manual labels in the dataset. To this end, we have developed a novel label refinement method based on an iterative generative adversarial network (GAN). Our iterative GAN is trained based on a set of high-quality patches (i.e. with consistent manual labels among different observers) and low-quality patches with noisy manual vessel labels. A simple yet effective method has been designed to simulate low-quality patches with noises which conform to the distribution of real noises from human observers. To evaluate the effectiveness of our method, we have trained four state-of-the-art retinal vessel segmentation models using the purified dataset obtained from our method and compared their performance with those trained based on the original noisy datasets. Experimental results on two datasets DRIVE and CHASE_DB1 demonstrate that obvious accuracy improvements can be achieved for all the four models when using the purified datasets from our method.
Enhancing coherency analysis for fault detection and mapping using 3D diffraction imaging (2006)

Automatic detection of geological discontinuities such as small throw faults, and pinch‐outs is an important problem in the interpretation of 3D seismic data. This is commonly done using coherency analysis. However coherency may be affected by noise, which may create false anomalies. We propose a new interpretation workflow for the detection and mapping of faults, which enhances the coherency‐type analysis with identification and detection of diffractions produced by the discontinuities. The algorithm utilizes migrated and unmigrated stacked seismic volumes and the cube of stacking (NMO) velocities. Tests on a simple 2.5 D model show that the method is capable in detecting and mapping of faults below seismic resolution.
Myocardial transcription factors are modulated during pathologic cardiac hypertrophy in vivo (2006)

The shunted neonatal lamb is a valid, novel model of pathologic biventricular hypertrophy. During pathologic hypertrophy myocardial transactivators are upregulated while repressors are downregulated.
In Vivo Evaluation of an Intraventricular Electric Axial Flow Pump for Left Ventricular Assistance (1994)

In vivo studies have begun to evaluate a new intraventricular electric axial flow left ventricular assist device (LVAD), the Jarvik 2000, which is a small, valveless pump that is placed inside the left ventricle through the left ventricular apex. The operation, which is performed through a left thoracotomy, may be done without cardiopulmonary bypass and aortic cross-clamping. Outflow is provided through a 16 mm softly woven, Dacron graft anastomosed to the descending thoracic or abdominal aorta. Pump flow, which varies from 2 to 16 l/min in vitro, is changed by adjusting the speed of pump rotation. Preliminary studies were done to evaluate the ease of implantation, hematologic and anatomic compatibility, and pump performance. The device has been implanted in seven healthy, preconditioned calves (83-138 kg), one of which is currently undergoing support. The implantation procedure averaged 3 hours. There were no operative deaths, and blood transfusions were not required. Postoperatively, anticoagulation was achieved with heparin followed by warfarin sodium to maintain prothrombin time or partial thromboplastin time at 1.5-2.0 times baseline. In the six completed studies, support time ranged from 2 to 120 days (mean, 36 days). The seventh calf has been supported for 30 days. In the four long-term studies (20, 70, 120, > 30 days), the mean plasma free hemoglobin values during support were 11.0, 7.7, 6.6, and 3.4 mg/dl, respectively. Under normal conditions, the average daily flow rate ranged from 5 to 6 l/min. During treadmill exercise (10% grade, 1.5 km/h) lasting 20 minutes, peak flow rates exceeded 8 l/min. These pilot studies suggest that this intraventricular axial flow pump is relatively easy to implant, operate, and control. In addition, it is hemocompatible, provides physiologic flow rates, and may be able to provide long-term circulatory support.
Watch Your Distance: The Role of Laser Fiber Working Distance on Fragmentation When Altering Pulse Width or Modulation (2018)

Holmium laser lithotripsy is significantly affected by fiber working distance with the greatest ablation obtained with the fiber in contact with the stone. At 0 and 1 mm distance, MD had the greatest fragmentation efficiency, suggesting this mode may have advantages during ureteroscopy.
Pulmonary atresia and a ventricular septal defect: about size and strategy (2015)

status: Published
Vision‐based human motion tracking using head‐mounted cameras and fixed cameras (2007)

Abstract In this paper, we propose a method to track human motions by using multiple‐viewpoint images taken by both mobile cameras and fixed‐viewpoint cameras. In a vision‐based system, the variety of viewpoints is important for effective detection/tracking of target motions. As image sequences observed from various viewpoints contain rich information regarding entire scenes, these images are also useful for video‐based analysis of human behaviors/interactions. We employ multiple numbers of mobile cameras mounted on human heads and fixed‐viewpoint cameras to observe a human interaction scene. In our method, 3D human positions are tracked by using both mobile and fixed‐viewpoint camera images. Transitions of human and background positions in images are estimated by using the tracked 3D positions, and the positions and poses of the mobile camera are determined by comparing the observed images with the estimation. Consequently, our method can provide position information for all humans and head motions for the humans wearing head‐mounted cameras. Experimental results show the effectiveness of the proposed method. © 2007 Wiley Periodicals, Inc. Electron Comm Jpn Pt 2, 90(2): 40–53, 2007; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/ecjb.20331