gebhart/patrepeval huggingface dataset:
Wideband Time Delay Signature-Suppressed Chaos Generation Using Self-Phase-Modulated Feedback Semiconductor Laser Cascaded With Dispersive Component (2019)

We propose a wideband chaos generation scheme that shows significant bandwidth enhancement and excellent time delay signature (TDS) suppression, by introducing self-phase modulation in the feedback loop of external-cavity semiconductor laser (ECSL) and passing the ECSL-generated chaos through a dispersive component. Proof-of-concept experiment and thorough complementary numerical simulations are carried out to study the efficient bandwidth and TDS characteristics of the generated chaos. The results demonstrate that with the joint contributions of self-phase modulation and dispersion, the efficient bandwidth of chaos can be enhanced by several times and the spectrum gets much flatter. Simultaneously, the TDS can be completely suppressed, in a wide operation parameter range. The proposed wideband chaos generation scheme shows great potential for the applications of fast random bit generation, high-resolution chaotic radar, and high-speed chaos communication.
Collusion-Resilient Fingerprinting by Random Pre-Warping (2004)

Fingerprinting of audio-visual content using digital watermarks is an effective means of determining originators of unauthorized/pirated copies. Watermarks embedded in content can trace the traitor responsible for piracy. Multiple users may, however, collude and collectively escape identification by creating an average of their individually watermarked copies that appears unwatermarked. We propose a novel collusion-resilience mechanism, wherein the host signal is warped randomly prior to watermarking. As each copy undergoes a distinctive warp, collusion through averaging either yields low-quality results or requires substantial computational resources to undo random warps. The method is independent of the watermarking scheme used and imposes no restrictions on the watermark signal. We demonstrate the effectiveness of this approach on digital images.
N-アセチルラクトサミン・キトビオースのアノマー位活性化および部分保護 (1991)

糖鎖合成における従来法より効果的な新規ブロック合成法の確立のため､近年酵素合成可能となった二糖(N-アセチルラクトサミン､キトビオース)を用いて､アノマー位の活性化および部分保護について検討を行った結果､グリコシド化反応においてビリジニウム-p-トルエンスルホナート(PPTS)が2-アミノ糖で一般に用いられる酸触媒よりも効果的であることが判明した｡
Session details: Heterogeneous Computing in Data Centers for Energy Efficiency (2016)

No abstract available.
A steganalysis system utilizing temporal pixel correlation of HEVC video (2015)

High Efficiency Video Coding (HEVC) is the most recent video codec coming after currently most popular H.264/MPEG4 codecs and has promising compression capabilities. It is conjectured that it will be a substitute for current video compression standards. However, to the best knowledge of the authors, none of the current video steganalysis methods designed or tested with HEVC video. In this paper, pixel domain steganography applied on HEVC video is targeted for the first time. Also, its the first paper that employs accordion unfolding transformation, which merges temporal and spatial correlation, in pixel domain video steganalysis. With help of the transformation, temporal correlation is incorporated into the system. Its demonstrated for three different feature sets that integrating temporal dependency substantially increased the detection accuracy.
Auf dem Weg zu makrocyclischen para‐Phenylenen (1993)

On the Way to Macrocyclic para‐ Phenylenes Strategies are presented to synthesize the hitherto unknown [O n ]Paracyclophanes 1 . Open chain belt‐type molecules based on 1,4‐connected carbocyclic six‐membered rings were prepared. Functionalization of the outer rings in 4‐position is the prerequisite for cyclization or lengthening of the molecular belts. In order to obtain the macrocyclic target molecules 1 , well preorganized cis ‐isomers of 1,4‐disubstituted cyclohexanes were prepared. X‐ray structural analyses reveal the static stereochemistry of the intermediates 8, 9, 17, 18 , and 24 . The macrocyclic hydrocarbon 29 containing five cyclohexylidene units was detected.
Learning to Extract Signature and Reply Lines from Email. (2004)

We describe methods for automatically identifying signature blocks and reply lines in plain-text email messages. This analysis has many potential applications, such as preprocessing email for text-to-speech systems; anonymization of email corpora; improving automatic content-based mail classifiers; and email threading. Our method is based on applying machine learning methods to a sequential representation of an email message, in which each email is represented as a sequence of lines, and each line is represented as a set of features. We compare several state-of-the-art sequential and non-sequential machine learning algorithms on different feature sets, and present experimental results showing that the presence of a signature block in a message can be detected with accuracy higher than 97%; that signature block lines can be identified with accuracy higher than 99%; and that signature block and reply lines can be simultaneously identified with accuracy of higher than 98%.
Molecular cloning and characterization of the Endo B cytokeratin expressed in preimplantation mouse embryos. (1986)

A cDNA clone of a keratin-related, intermediate filament protein, designated Endo B, was constructed from size-fractionated parietal endodermal mRNA and characterized. The 1466-nucleotide cDNA insert contains an open reading frame of 1272 nucleotides that would result in 5' and 3' noncoding sequences of 54 and 60 nucleotides, respectively. The predicted amino acid composition, molecular weight (47,400), and peptide pattern correlate well with data obtained on the isolated protein. The predicted amino acid sequence fits easily into the general domain structure suggested for all intermediate filament proteins with a unique amino-terminal head domain, a large conserved central domain of predominantly alpha-helical structure, and a relatively unique carboxyl-terminal or tail domain. Over the entire molecule, Endo B is 43% identical with human 52-kDa epidermal type I keratin. However, over two of the three regions contained in the central domain that are predicted to form coiled-coil structures, the Endo B is 54-68% identical with other type I keratin sequences. This homology, along with the presence of the completely conserved sequence DNARLAADDFR-KYE, which is found in all type I keratins, permits the unambiguous identification of Endo B as a type I keratin. Comparison of the Endo B sequence to other intermediate filament proteins reveals 22 residues which are identical in all intermediate filament proteins regardless of whether filament formation requires only one type of protein subunit (vimentin, desmin, glial fibrillar acidic protein, or a neurofilament protein) or two dissimilar types (type I and type II keratins). Endo B mRNA was detectable in RNA isolated from F9 cells treated with retinoic acid for 48 h. Approximately three to five genes homologous to Endo B were detected in the mouse genome.
Visual Vehicle Tracking Through Noise and Occlusions Using Crowd-Sourced Maps (2018)

We present a location-specific method to visually track the positions of observed vehicles based on large-scale crowd-sourced maps. We equipped a large fleet of cars that drive around cities with camera phones mounted on the dashboard, and performed city-scale structure-from-motion to accurately reconstruct the trajectories taken by the vehicles. We show that these data can be used to first create a system enabling high-accuracy localisation, and then to accurately predict the future motion of newly observed cars in the camera view. As a basis for the method we use a recently proposed system [1] for unsupervised motion prediction and extend it to a real-time visual tracking pipeline which can track vehicles through noise and extended occlusions using only a monocular camera. The system is tested using two large-scale datasets of San Francisco and New York City containing millions of frames. We demonstrate the performance of the system in a variety of traffic, time, and weather conditions. The presented system requires no manual annotation or knowledge of road infrastructure. To our knowledge, this is the first time a perception system based on a large-scale crowd-sourced maps has been evaluated at this scale.
Space‐Varying Regression Coefficients: A Semi‐parametric Approach Applied to Real Estate Markets (2000)

This paper presents a method for estimating home values by non‐parametrically incorporating the physical location of the properties. Specifically, I allow the parameters of the observed covariates to vary in space. This approach mitigates one of the biggest deficiencies inherent in hedonic pricing models–omitted variables. I demonstrate the advantages of the proposed method using real estate transaction data from Los Angeles County. The estimation finds a substantial spatial variation of the marginal values of the hedonic characteristics and provides an insight into the segmentation of the market. The proposed method is an extension of semi‐parametric multi‐dimensional k‐nearest‐neighbor smoothing. It alleviates a fundamental problem known as the curse of dimensionality by incorporating parametric components into a non‐parametric estimation.
Three-dimensional phononic crystal with ultra-wide bandgap at megahertz frequencies (2021)

Phononic crystals have attracted wide attention in diverse scientific communities due to their ability to efficiently reflect, focus, and guide acoustic and elastic waves. Their use in ultrasonic applications such as medical imaging, however, remains elusive since three-dimensional phononic crystals with lattice constants in the range of hundreds of micrometers are required to operate with MHz ultrasound, smaller than what most additive manufacturing solutions can provide. This work presents a three-dimensional phononic crystal with a cubic symmetry having an experimental ultra-wide complete bandgap extending from 0.6 MHz to 7.5 MHz. Crystal specimens are manufactured using two-photon lithography at the microscale, with a lattice constant of 300 μm, and are characterized using heterodyne interferometry.
Interactions between Subunits in Heterodimeric Ncd Molecules (2009)

The nonprocessive minus-end-directed kinesin-14 Ncd is involved in the organization of the microtubule (MT) network during mitosis. Only one of the two motor domains is involved in the interaction with the MT. The other head is tethered to the bound one. Here we prepared, purified, and characterized mutated Ncd molecules carrying point mutations in one of the heads, thus producing heterodimeric motors. The mutations tested included substitutions in Switch I and II: R552A, E585A, and E585D; the decoupling mutant N600K; and a deletion in the motor domain in one of the subunits resulting in a single-headed molecule (NcN). These proteins were isolated by two sequential affinity chromatography steps, followed by measurements of their affinities to MT, enzymatic properties, and the velocity of the microtubule gliding test in vitro. A striking observation is a low affinity of the single-headed NcN for MT both without nucleotides and in the presence of 5'-adenylyl-beta,gamma-imidodiphosphate, implying that the tethered head has a profound effect on the structure of the Ncd-MT complex. Mutated homodimers had no MT-activated ATPase and no motility, whereas NcN had motility comparable with that of the wild type Ncd. Although the heterodimers had one fully active and one inactive head, the ATPase and motility of Ncd heterodimers varied dramatically, clearly demonstrating that interactions between motor domains exist in Ncd. We also show that the bulk property of dimeric proteins that interact with the filament with only one of its heads depends also on the distribution of the filament-interacting subunits.
The Relationship Between Maternal and Neonatal Microbiota in Spontaneous Preterm Birth: A Pilot Study (2022)

The newborn's microbiota composition at birth seems to be influenced by maternal microbiota. Maternal vaginal microbiota can be a determining factor of spontaneous Preterm Birth (SP<sup>PTB</sup>), the leading cause of perinatal mortality. The aim of the study is to investigate the likelihood of a causal relationship between the maternal vaginal microbiota composition and neonatal lung and intestinal microbiota profile at birth, in cases of SP<sup>PTB</sup>. The association between the lung and/or meconium microbiota with the subsequent development of bronchopulmonary dysplasia (BPD) was also investigated. Maternal vaginal swabs, newborns' bronchoalveolar lavage fluid (BALF) (1st, 3rd, 7th day of life) and first meconium samples were collected from 20 women and 23 preterm newborns with gestational age ≤ 30 weeks (12 = SP<sup>PTB</sup>; 11 = Medically Indicated Preterm Birth-MI<sup>PTB</sup>). All the samples were analyzed for culture examination and for microbiota profiling using metagenomic analysis based on the Next Generation Sequencing (NGS) technique of the bacterial 16S rRNA gene amplicons. No significant differences in alpha e beta diversity were found between the neonatal BALF samples of SP<sup>PTB</sup> group and the MI<sup>PTB</sup> group. The vaginal microbiota of mothers with SP<sup>PTB</sup> showed a significant difference in alpha diversity with a decrease in Lactobacillus and an increase in Proteobacteria abundance. No association was found between BALF and meconium microbiota with the development of BPD. Vaginal colonization by Ureaplasma bacteria was associated with increased risk of both SP<sup>PTB</sup> and newborns' BPD occurrence. In conclusion, an increase in α-diversity values and a consequent fall in Lactobacillus in vaginal environment could be associated to a higher risk of SP<sup>PTB</sup>. We could identify neither a specific neonatal lung or meconium microbiota profiles in preterm infants born by SP<sup>PTB</sup> nor a microbiota at birth suggestive of subsequent BPD development. Although a strict match has not been revealed between microbiota of SP<sup>PTB</sup> mother-infant couples, a relationship cannot be excluded. To figure out the reciprocal influence of the maternal-neonatal microbiota and its potential role in the pathogenesis of SP<sup>PTB</sup> and BPD further research is needed.
Low-threshold strain-compensated InGaAs(N) (/spl lambda/ = 1.19-1.31 μm) quantum-well lasers (2002)

Highly strained (/spl Delta/a/a /spl sim/ 2.5%) In/sub 0.4/Ga/sub 0.6/As and In/sub 0.4/Ga/sub 0.6/As/sub 0.995/N/sub 0.005/-quantum-well (QW) active lasers utilizing strain-compensating InGaP-GaAsP buffer layers and GaAs/sub 0.85/P/sub 0.15/ barrier layers, grown by metal-organic chemical vapor deposition (MOCVD), are demonstrated with lasing emission wavelength of 1.185 and 1.307 μm, respectively. Threshold and transparency current density for the strain compensated InGaAsN QW lasers, with emission wavelength of 1.295 μm, are measured to be as low as 290 A/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> (L = 1500 μm) and 110 A/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> , respectively, with characteristic temperature of T <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> and T <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sub> of 130 K and 400 K.
The Scirtothrips perseae species-group (Thysanoptera), with one new species from avocado, Persea americana (2016)

Following recent molecular studies on avocado thrips, a new species is described from Costa Rica, Ecuador, and Colombia from the young leaves of avocado, Persea americana. Scirtothrips hansoni sp.n. is closely related to the Californian pest, S. perseae, and also to S. astrictus from Costa Rica that remains known from a single female. An illustrated key to these three species is provided.
Preparation and Characterization of Polymer/Date Pits Composites (2009)

This research reports the formulation and characterization of polymer/date pits composites. Polymers used in this study were high-density polyethylene (HDPE) and polystyrene (PS), while date pits used were locally called khlaas (K) and sekari (S), wastes of two types of date palm fruit grown in Saudi Arabia. Tensile strength (TS) and Izod impact strength (IIS) tests were conducted to assess the mechanical properties of the prepared composites. Thermal properties of the composites were measured and discussed in view of glass transition and melting temperatures, T g and T m , respectively, as well as the heat of fusion, which reflects the degree of crystallinity of the polymer/date pits composites. Generally, mechanical properties, i.e., TS and IIS, were reduced upon date pits incorporation in the composites. Results showed that IIS of HDPE/date pits composites drastically suffered from the addition of as low as 5 wt% of date pits. Addition of date pits regardless of the type, either S or K, tended to reduce T g of the PS100/date pits composites and the heat of fusion of the HDPE/date pits composites at relatively higher date pits content, &gt;10 wt%. The reduction in both degree of crystallinty represented by heat of fusion of the HDPE and mechanical properties of all composite systems used in this study at the high loading presence of date pits may be related to the anticipated coarse morphology of the composites evolved during the mixing of polymers, with date pits in the absence of an appropriate coupling agent system.
BUILDING A NATIONAL EVALUATION SYSTEM FOR HIGHER EDUCATION: LESSONS FROM DIVERSE SETTINGS (1995)

Basing himself on his long experience of consulting on three continents, the author presents the lessons derived from the experiences of countries in different cultural, legal, economic, and political circumstances as they developed or reformed evaluation schemes for institutions and programmes. The influencing factors, general patterns expressed to date, likely trends, and questions which should be addressed by those seeking to establish such systems are presented. The ability to develop among and within the institutions a culture and infrastructure of self‐regulation is viewed as the major influential condition, in the long run, in the establishment of effective systems, in light of the major intentions commonly put forth.
The subunits of human hexosaminidase A (1976)

Previous studies of the subunit structure of hexosaminidase gave ambiguous results, but suggested that the enzyme was composed of six equally sized subunits. Dissociation of hexosaminidase A with p-chloromercuribenzoate produces an alkylated fragment with mol.wt. approx. 50000, which is converted into hexosaminidase S by treatment with dithiothreitol. Treatment of native hexosaminidase A with sodium dodecylsulphate results in the formation of a large and a small fragment. However, although the native enzyme has a sedimentation coefficient of 5.8S, dissociation by S-carboxymethylation and maleic anhydride treatment results in subunits exhibiting a single schlieren boundary on analytical ultracentrifugation with a sedimentation coefficient of 2.18S. These results indicate that the enzyme is composed of four subunits, each with molwt. approx. 25000-27000. The mol.wt. of the native enzymes is calculated to be approx. 110000. Our data are consistent with the subunit structures of hexosaminidases A, B and S as being alpha2beta2, beta4 and alpha4 respectively.
IUPHAR-DB: An Expert-Curated, Peer-Reviewed Database of Receptors and Ion Channels (2009)

Abstract The International Union of Basic and Clinical Pharmacology database (IUPHAR-DB) integrates peer-reviewed pharmacological, chemical, genetic, functional and anatomical information on the 354 non-sensory G protein-coupled receptors (GPCRs), 71 ligand-gated ion channel subunits and 141 voltage-gated ion channel subunits encoded by the human, rat and mouse genomes. These genes represent the targets of about a third of currently approved drugs and are a major focus of drug discovery and development programs in the pharmaceutical industry. Individual gene pages provide a comprehensive description of the genes and their functions, with information on protein structure, ligands, expression patterns, signaling mechanisms, functional assays and biologically important receptor variants (e.g. single nucleotide polymorphisms and splice variants). The phenotypes resulting from altered gene expression (e.g. in genetically altered animals) and genetic mutations are described. Links are provided to bioinformatics resources such as NCBI RefSeq, OMIM, PubChem, human, rat and mouse genome databases. Recent developments include the addition of ligand-centered pages summarising information about unique ligand molecules in IUPHAR-DB. IUPHAR-DB represents a novel approach to biocuration because most data are provided through manual curation of published literature by a network of over 60 expert subcommittees coordinated by NC-IUPHAR. Data are referenced to the primary literature and linked to PubMed. The data are checked to ensure accuracy and consistency by the curators, added to the production server using custom-built submission tools and peer-reviewed by NC-IUPHAR, before being transferred to the public database. Data are reviewed and updated regularly (at least biennially). Other website features include comprehensive database search tools, online and downloadable gene lists and links to recent publications of interest to the field, such as reports on receptor-ligand pairings. The database is freely available at "http://www.iuphar-db.org":http://www.iuphar-db.org. Curators can be reached at curators [at] iuphar-db.org. We thank British Pharmacological Society, UNESCO (through the ICSU Grants Programme), Incyte, GlaxoSmithKline, Novartis, Servier and Wyeth for their support.
Immune response to 100 mg gluten introduced at 4 months of age: results from the PreventCD cohort. (2011)

Immune response to 100 mg gluten introduced at 4 months of age: results from the PreventCD cohort.
Building a high-performance deduplication system (2011)

Modern deduplication has become quite effective at eliminating duplicates in data, thus multiplying the effective capacity of disk-based backup systems, and enabling them as realistic tape replacements. Despite these improvements, single-node raw capacity is still mostly limited to tens or a few hundreds of terabytes, forcing users to resort to complex and costly multi-node systems, which usually only allow them to scale to singledigit petabytes. As the opportunities for deduplication efficiency optimizations become scarce, we are challenged with the task of designing deduplication systems that will effectively address the capacity, throughput, management and energy requirements of the petascale age. In this paper we present our high-performance deduplication prototype, designed from the ground up to optimize overall single-node performance, by making the best possible use of a node’s resources, and achieve three important goals: scale to large capacity, provide good deduplication efficiency, and near-raw-disk throughput. Instead of trying to improve duplicate detection algorithms, we focus on system design aspects and introduce novel mechanisms—that we combine with careful implementations of known system engineering techniques. In particular, we improve single-node scalability by introducing progressive sampled indexing and grouped markand-sweep, and also optimize throughput by utilizing an event-driven, multi-threaded client-server interaction model. Our prototype implementation is able to scale to billions of stored objects, with high throughput, and very little or no degradation of deduplication efficiency. 1