gebhart/patrepeval huggingface dataset:
Empowerment for diabetes management: integrating true self-management into the medical treatment and management of diabetes mellitus. (2001)

Approximately 16 million people in the United States have diabetes mellitus, and the number of diagnoses is increasing at an alarming rate. A very costly disease in both human and economic terms, diabetes (currently the seventh leading cause of death) is common in both the old and young, crossing all racial, ethnic, and economic barriers. Diabetes significantly increases the risk of cardiovascular, cerebrovascular, and peripheral vascular disease, retinopathy, neuropathy, and nephropathy. The team approach to treating and managing diabetes provides a foundation of support and education for the patient, while allowing the individual control of his or her health care decisions. A self-management education program is essential for diabetes patients and their support systems to learn optimal strategies for dealing with chronic illness and the associated physical and psychological obstacles. Diabetes education must motivate and empower patients with instruction in self-monitoring techniques, proper nutrition and exercise, pharmacologic options, and psychosocial adjustments to depression and stress brought on by chronic disease, as well as provide resources for continuing education. Ochsner is developing a system-wide diabetes self-management education program as a resource for all of Louisiana and parts of Mississippi to improve the outcomes of diabetic patients. The program has demonstrated significant results since 1998 by providing a comprehensive foundation to patients and their support systems and providing a foundation for the lifelong quest to master the chronic disease process.
Digitally-Calibrated Reconfigurable Analog-to-Digital Converters (2013)

Modern digital communication systems target satisfying multiple standards and different operating scenarios. Applications include read channels of data storage systems, PCIe links, FPGA I/Os, and multi-standard radios. This stimulates the research on reconfigurable analog-to-digital converters (ADCs) to serve as a key building block at the front-end of such systems. Conventional reconfigurable designs suffer from poor figure-of-merit (FoM) scaling with different resolutions, which reduces their flexibility. The limited efficiency of these techniques is attributed to the fact that they fix the ADC architecture for all configurations, whereas the optimum architecture depends on the target resolution. This dissertation introduces an architecture reconfigurable ADC that efficiently covers a wide range of resolutions by configuring the ADC to the proper architecture for each resolution. This leads to a reconfigurable ADC nearly as efficient as dedicated designs in both area and power. Device matching is the heart of precision analog design. Basically, well matched devices come at the expense of larger die, parasitic capacitance and power consumption. Instead of only sizing the devices to achieve the desired accuracy, the intrinsic accuracy of an area efficient converter is designed worse than its resolution. Before or during chip usage, self-calibration automatically detects and corrects for elements mismatches and leads to reduced silicon area and improved yield. This dissertation investigates the efficiency of using body voltage trimming calibration for data converters. The tradeoffs of this technique are studied in details. Suggested methods have been presented to extend the use of bulk voltage trimming beyond technology limitations with minimal area and power overhead and no special technology requirements. The study shows that best results are achieved when mixing bulk trimming with other calibration techniques.Two prototype chips are implemented in 65-nm CMOS to verify the results of this study. The first chip is a 2.5-10GS/s reconfigurable flash ADC. The ADC can be configured to work as a 3-bit, a 4-bit, or a 5-bit ADC with worst case integral nonlinearity (INL) and differential nonlinearity (DNL) of 0.48LSB and 0.35LSB respectively. The ADC achieves a figure-of-merit of 0.46pJ/conv-step and the active area is 0.13mm2. The second chip is a 1.5-4GS/s "architecture" reconfigurable ADC. The ADC covers resolution range from 3b to 7b, and achieves a figure-of-merit of 0.46pJ/conv-step at 7-bit and the active area is 0.15mm2.
Reduced Myocardial Perfusion Reserve in Type 2 Diabetes Is Caused by Increased Perfusion at Rest and Decreased Maximal Perfusion During Stress (2020)

Patients with type 2 diabetes have higher global MBF at rest and lower maximal MBF during vasodilator-induced stress than control subjects. Reduced MBF during stress is associated with diabetes complications (albuminuria and retinopathy) and is inversely correlated with diffuse myocardial fibrosis.
Online Monitoring of Dynamics withPMUData (2016)

Abstract Power system frequency, voltage, and current measurements, obtained from phasor measurement units (PMUs), provide several important capabilities beyond the traditional 4‐s substation data used in the energy management systems of control centers. These properties include precise time tagging of the measured data using GPS (global positioning system) signals, high sampling rate at 30/50/60 samples per second, and the phase as well as the magnitude of the voltage and current phasors. Thus, the PMU data can be used to monitor power system dynamics, such as the impact of a disturbance as it spreads to other regions, and oscillations during disturbances and under ambient condition. This chapter reviews the PMU data application tools that have been installed at control centers or are under development.
Deterrence of Diamondback Moth (Lepidoptera: Plutellidae) Oviposition by Plant Compounds (1985)

Diamondback moth, Plutella xylostella (L.), oviposition was deterred by spraying the plant secondary compounds coumarin and rutin on cabbage plants in laboratory choice tests. Deterrent effects of the compounds were not reduced when females were exposed to treated plants for 48 h. Coumarin was a more potent deterrent in darkness (4.1-fold) than in light (2.3-fold), but rutin's effect was stronger in light (3.2-fold) than in darkness (1.9-fold). Results support the view that diamondback moth oviposition is mediated by several sensory modalities including vision, chemoreception, and mechanoreception.
Advanced and innovative chromatographic techniques for the study of citrus essential oils (2005)

Abstract A brief description is given of advanced chromatographic techniques currently employed in citrus essential oil analysis (the interactive use of linear retention indices and MS spectra probability matching in GC–MS; on‐line ‘heart cutting’ multidimensional chromatographic techniques, comprehensive GC and LC; fast GC and GC–MS; fast HPLC; HPLC–MS). A series of applications are reported, demonstrating both the valid and the potential of these methods. Copyright © 2005 John Wiley &amp; Sons, Ltd.
Improving Information Extraction through Biological Correlation (2003)

We present a new method for improving the efficiency of information extraction systems applied to biological literature, using the correlation between structural and functional classifications of gene products. The method evaluates extracted information by checking if gene products from a common family match a common set of biological properties. To evaluate the method, we implemented it in a case-study, where the method annotated carbohydrate-active enzymes with functional properties extracted from literature. Each carbohydrateactive enzyme is assigned to one or more families of catalytic and carbohydrate-binding modules according to its modular structure. To compute the relatedness between functional properties, we implemented a semantic similarity measure in GO, a biological ontology. The results present our quantitative measure of the correlation between the modular structures and functional properties, showing that our method is a viable approach for automatic validation of extracted biological information. 1.
Dissociation of sodium-chloride cotransporter expression and blood pressure during chronic high dietary potassium supplementation (2023)

Dietary potassium (K+) supplementation is associated with a lowering effect in blood pressure (BP), but not all studies agree. Here, we examined the effects of short- and long-term K+ supplementation on BP in mice, whether differences depend on the accompanying anion or the sodium (Na+) intake and molecular alterations in the kidney that may underlie BP changes. Relative to the control diet, BP was higher in mice fed a high NaCl (1.57% Na+) diet for 7 weeks or fed a K+-free diet for 2 weeks. BP was highest on a K+-free/high NaCl diet. Commensurate with increased abundance and phosphorylation of the thiazide sensitive sodium-chloride-cotransporter (NCC) on the K+-free/high NaCl diet, BP returned to normal with thiazides. Three weeks of a high K+ diet (5% K+) increased BP (predominantly during the night) independently of dietary Na+ or anion intake. Conversely, 4 days of KCl feeding reduced BP. Both feeding periods resulted in lower NCC levels but in increased levels of cleaved (active) α and γ subunits of the epithelial Na+ channel ENaC. The elevated BP after chronic K+ feeding was reduced by amiloride but not thiazide. Our results suggest that dietary K+ has an optimal threshold where it may be most effective for cardiovascular health.
Hot Melt Inks for 3D Printing (2005)

A unique modified formula of hot-melt ink for phase change printing process was developed. A composition useful for 3D printing comprises different waxes, tackifier and plasticizer resins, rheology modifiers, and UV curable resin and/or gas releasing agent. Differential scanning calorimetry was used to evaluate thermal properties of the ink components and the extensive study of the thermal behavior of the proposed gas releasing agents has been carried out. The rheology behavior of inks and printability such as image detail, definition of dots (sharpness of the edges), dot formation, and spreading were investigated.Dot heights were measured by a modified method using a First Ten Angstrom dynamic contact angle instrument. Sutherland Rub resistance test was also used together with tape adhesion tests for ink adhesion monitoring.
General Multicomponent Strategy for the Synthesis of 2‐Amino‐1,4‐diazaheterocycles: Scope, Limitations, and Utility (2010)

Abstract Multicomponent reactions of primary 1,2‐ and 1,3‐diamines with carbonyl compounds and isocyanides resulting in the formation of diverse 2‐amino‐1,4‐diazaheterocycles are described. Lewis acids (LAs) promote the reactions effectively, and chlorotrimethylsilane (TMSCl) has been found to be a promoter of choice. The scope and limitations of the reactions with regard to each of the components are evaluated and discussed. Post‐IMCR modifications of the synthesized heterocycles have been elaborated.
Cesteria n' Asturies. 'Cestería en Asturias' : los cesteros, goxeros o maconeros y mimbreros en Asturias (1993)

Se edito como memoria un video en la coleccion Temas de Cultura Asturiana con ISBN 84-88345-06-2 y D.L.: AS-1904/93
Versatile Post-Doping toward Two-Dimensional Semiconductors (2021)

We have developed a simple and straightforward way to realize controlled postdoping toward 2D transition metal dichalcogenides (TMDs). The key idea is to use low-kinetic-energy dopant beams and a high-flux chalcogen beam simultaneously, leading to substitutional doping with controlled dopant densities. Atomic-resolution transmission electron microscopy has revealed that dopant atoms injected toward TMDs are incorporated substitutionally into the hexagonal framework of TMDs. The electronic properties of doped TMDs (Nb-doped WSe<sub>2</sub>) have shown drastic change and <i>p-</i>type action with more than 2 orders of magnitude increase in current. Position-selective doping has also been demonstrated by the postdoping toward TMDs with a patterned mask on the surface. The postdoping method developed in this work can be a versatile tool for 2D-based next-generation electronics in the future.
Current Understanding of and Future Directions for Endometriosis-Related Infertility Research with a Focus on Ferroptosis (2023)

An analysis of the ferroptosis pathway in in vitro, in vivo, and animal research enhances our understanding of the pathogenesis of this disease. Here, we discuss the role of ferroptosis modulators as a research approach and potential novel treatment for endometriosis and disease-related infertility.
Abstract 4583: A blocking antibody to HB-EGF inhibits the growth of tumor xenograft (2011)

Abstract Heparin-binding epidermal growth factor (HB-EGF), a member of the EGF family of growth factors, is widely expressed in many human cancers compared with normal tissues. HB-EGF is initially produced as a membrane-anchored form (pro-HB-EGF) and later processed to a soluble form (s-HB-EGF), which exert its biological activity through activation of EGFR and EGFR4. A key role of HB-EGF in the acquisition of malignant phenotypes has been well documented, such as tumorigenicity, invasion, metastasis, angiogenesis, and resistance to chemotherapy. In this study, we demonstrate the potential of an anti-HB-EGF mAb for cancer therapy by generating a potent blocking monoclonal antibody, HC-15. The HC-15 mAb recognized both forms of HB-EGF, pro- and s-HB-EGF. HC-15 efficiently blocked the binding of HB-EGF to EGFR-Fc in the ELISA. Furthermore, HC-15 substantially inhibited the HB-EGF-dependent proliferation of the EGFR expressing Ba/F3 transfectant lines. To investigate the potential of HC-15 for cancer therapy, the in vivo antitumor activity of HC-15 was tested. Significant growth inhibition by treatment of HC-15 (10mg/kg once a week) was observed in established human tumor models, such as ovarian cancer (MCAS), pancreatic cancer (BXPC-3), and breast cancer (MDA-MB-231) in athymic nude mice. Thus, we conclude that the anti-HB-EGF mAb HC-15 has strong anti-tumor activity in various models, supporting the inhibition of HB-EGF functions by mAb is useful in cancer treatment. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research; 2011 Apr 2-6; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2011;71(8 Suppl):Abstract nr 4583. doi:10.1158/1538-7445.AM2011-4583
Immunocytochemistry of Pineal Astrocytes (1985)

Immunohistochemical demonstration of glial fibrillary acidic protein (GFAP) was performed in human, sheep, rat and guinea pig pineal bodies to determine if there were species differences. Specialized "basket-like" arrangements of many GFAP-positive astrocytic processes were shown around sheep pinealocytes. Human pineals contained scattered astrocytic cell bodies and a moderate number of GFAP-positive astrocytic processes which, as in sheep, also surrounded pinealocytes, but without the dense basket-like arrangements. In both species GFAP-positive fibers were concentrated at the periphery of pseudolobules and around blood vessels. Rat and guinea pig pineals contained only rare astrocytic cell bodies and few GFAP-positive fibers throughout the glands, but had a concentration of parallel GFAP-positive fibers at the stalk. GFAP-positive fibers in human and sheep pineals may be derived from both intra- and extraglandular sites, whereas in rodents only rare processes appear to be derived from within the gland. Astrocytes may play a role in modulation of pineal indoleamines and norepinephrine, and the species differences observed suggest that this effect may be important in sheep and human pineals but not in rodents.
Chirality Control and Its Memory at Microphase-Separated Interface of Self-Assembled Chiral Block Copolymers for Nanostructured Chiral Materials (2017)

Here, we show the induced chirality of an achiral chromophoric dye as a joint of polylactide-containing chiral block copolymers (BCPs*) driven by self-assembly, giving the achiral dyes preferentially arranged in a one-handed helical array at the microphase-separated interface. This helical arrangement of the achiral dyes can be "memorized" after hydrolysis of the polylactides in the BCPs* and serves as a chiral template for further chirality induction of different achiral dyes, probably through attractive aromatic π-π interactions at the interface, producing nanostructured chiral materials with tunable circular dichroism signals at desired wavelengths.
The Menopause Rating Scale (MRS) scale: A methodological review (2004)

Abstract Background This paper compiles data from different sources to get a first comprehensive picture of psychometric and other methodological characteristics of the Menopause Rating Scale (MRS) scale. The scale was designed and standardized as a self-administered scale to (a) to assess symptoms/complaints of aging women under different conditions, (b) to evaluate the severity of symptoms over time, and (c) to measure changes pre- and postmenopause replacement therapy. The scale became widespread used (available in 10 languages). Method A large multinational survey (9 countries in 4 continents) from 2001/ 2002 is the basis for in depth analyses on reliability and validity of the MRS. Additional small convenience samples were used to get first impressions about test-retest reliability. The data were centrally analyzed. Data from a postmarketing HRT study were used to estimate discriminative validity. Results Reliability measures (consistency and test-retest stability) were found to be good across countries, although the sample size for test-retest reliability was small. Validity: The internal structure of the MRS across countries was astonishingly similar to conclude that the scale really measures the same phenomenon in symptomatic women. The sub-scores and total score correlations were high (0.7–0.9) but lower among the sub-scales (0.5–0.7). This however suggests that the subscales are not fully independent. Norm values from different populations were presented showing that a direct comparison between Europe and North America is possible, but caution recommended with comparisons of data from Latin America and Indonesia. But this will not affect intra-individual comparisons within clinical trials. The comparison with the Kupperman Index showed sufficiently good correlations, illustrating an adept criterion-oriented validity. The same is true for the comparison with the generic quality-of-life scale SF-36 where also a sufficiently close association has been shown. Conclusion The currently available methodological evidence points towards a high quality of the MRS scale to measure and to compare HRQoL of aging women in different regions and over time, it suggests a high reliability and high validity as far as the process of construct validation could be completed yet.
Nearly all hereditary paragangliomas in The Netherlands are caused by two founder mutations in the SDHD gene (2001)

Hereditary paragangliomas or glomus tumors are usually benign slow-growing tumors in the head and neck region. The inheritance pattern of hereditary paraganglioma is autosomal dominant with imprinting. Recently, we have identified the SDHD gene encoding subunit D of the mitochondrial respiratory chain complex II as one of the genes involved in hereditary paragangliomas. Here, we demonstrate that two founder mutations, Asp92Tyr and Leu139Pro, are responsible for paragangliomas in 24 and 6 of the 32 independently ascertained Dutch paraganglioma families, respectively. These two mutations were also detected among 20 of 55 isolated patients. Ten of the isolated patients had multiple paragangliomas, and in eight of these SDHD germline mutations were found, indicating that multicentricity is a strong predictive factor for the hereditary nature of the disorder in isolated patients. In addition, we demonstrate that the maternally derived wild-type SDHD allele is lost in tumors from mutation-carrying patients, indicating that SDHD functions as a tumor suppressor gene.
Output regulation of heterogeneous linear multi-agent systems with differential graphical game (2015)

This paper addresses output regulation of heterogeneous linear multi-agent systems. We first show that output regulation can be achieved through local controller design, then we formulate output regulation in the graphical game framework. To solve output regulation of heterogeneous linear multi-agent system in the graphical game framework, one needs to derive a solution to the coupled Hamilton–Jacobi equations. Both offline and online algorithms are suggested for that solution. Using the online method, the profile policy converges to a Nash Equilibrium. Besides, it is shown that the graphical formulation is robust to the multiplicative uncertainty satisfying an upper bound and it has an infinite gain margin. Copyright © 2015 John Wiley & Sons, Ltd.
Computer animation via optical video disc (1980)

Thesis (M.S.V.S.)--Massachusetts Institute of Technology, Dept. of Architecture, 1980.
Improving the Management of Diabetes in Hospitalized Patients: The Results of a Computer-Based House Staff Training Program (2012)

A computer-based diabetes training program can improve the comfort and knowledge of house staff and potentially improve their insulin administration practices at large academic centers.
A new video hard disk system for multimedia program production (1996)

This paper reports on a new video hard disk system for real-time recording and playing back of high-quality digital video signals, an important component in the production of multimedia programs at broadcasting stations. The paper clarifies some of the problems associated with the recording of high-quality video signals on a conventional hard disk system designed for storing computer data. It describes the requirements of a future video hard disk system. We have developed an experimental high-speed hard disk interface device suitable for transferring video signals. This device can guarantee continuous transfer of video signals with a high bit rate, sending them at 123 Mbps/ch-more than twice as fast as a conventional device. Using this interface, we have developed a video hard disk system capable of real-time recording and playing back of non-compressed video signals (conventional TV).
Effect of Playing a Video Game on a Measure of Spatial Visualization (1986)

70 undergraduate students, without any prior experience of video games playing, were given a pretest and a posttest on the Space Relations Test of the DAT, Forms A and B being, respectively, administered on the two occasions. The experimental group of 38 had eight sessions of playing the Zaxxon video game, each session including five plays. The control group of 32 received no such treatment. A 2 (sex) by 2 (group) analysis of covariance, using pretest scores as the covariate, yielded a significant effect for group which supports the hypothesis that spatial visualization test scores can be improved by video game playing. Moreover, the sex-related difference in visual-spatial skills frequently reported does not appear on the pretest. Finally, no effect for sex and no interaction of group X sex were found, indicating that both male and female subjects gained equally from playing Zaxxon.
Susceptibility of canine chondrocytes and synoviocytes to antibiotic cytotoxicity in vitro (2021)

These results provide evidence to justify future in vitro work with osteoarthritic joint tissues and in vivo clinical trials to evaluate safety and efficacy of intra-articular antibiotics to treat dogs with septic arthritis.