gebhart/patrepeval huggingface dataset:
Endometrial fibrinolytic enzymes in women with normal menstruation and dysfunctional uterine bleeding (1993)

There is a strong positive correlation between endometrial t-PA activity on the second day of menstruation and measured menstrual loss (P < 0.05). Concentrations of endometrial t-PAAg and PAI-1 antigen are higher in women with DUB compared with normal women during menstruation.
Simultaneous Information and Power Transfer for Broadband Wireless Systems (2013)

Far-field microwave power transfer (MPT) will free wireless sensors and other mobile devices from the constraints imposed by finite battery capacities. Integrating MPT with wireless communications to support simultaneous wireless information and power transfer (SWIPT) allows the same spectrum to be used for dual purposes without compromising the quality of service. A novel approach is presented in this paper for realizing SWIPT in a broadband system where orthogonal frequency division multiplexing and transmit beamforming are deployed to create a set of parallel sub-channels for SWIPT, which simplifies resource allocation. Based on a proposed reconfigurable mobile architecture, different system configurations are considered by combining single-user/multi-user systems, downlink/uplink information transfer, and variable/fixed coding rates. Optimizing the power control for these configurations results in a new class of multi-user power-control problems featuring the circuit-power constraints, specifying that the transferred power must be sufficiently large to support the operation of the receiver circuitry. Solving these problems gives a set of power-control algorithms that exploit channel diversity in frequency for simultaneously enhancing the throughput and the MPT efficiency. For the system configurations with variable coding rates, the algorithms are variants of water-filling that account for the circuit-power constraints. The optimal algorithms for those configurations with fixed coding rates are shown to sequentially allocate mobiles their required power for decoding in ascending order until the entire budgeted power is spent. The required power for a mobile is derived as simple functions of the minimum signal-to-noise ratio for correct decoding, the circuit power and sub-channel gains.
CentiTrack: Toward Centimeter-Level Passive Gesture Tracking With Commodity WiFi (2023)

Gesture awareness plays a crucial role in promoting human–computer interface. Previous works either depend on customized hardware or need a priori learning of wireless signal patterns, facing downsides in terms of the privacy concern, availability, and reliability. In this article, we propose CentiTrack, the first centimeter-level passive gesture-tracking system that works with only three commodity WiFi devices, without any extra hardware modifications or wearable sensors. To this end, we first identify the channel state information (CSI) measurement error sources in the physical-layer process, and then denoise CSI by the complex ratio between adjacent antennas. Principal component analysis (PCA) is further adopted to separate the reflected signals from noises. Benchmark experiments are conducted to verify that the phase changes of denoised CSI are proportional to the length changes of the dynamic path reflected off the hand. In addition, we adopt the multiple signal classification (MUSIC) algorithm to estimate the Angle-of-Arrivals (AoAs) of dynamic paths, and then locate the initial position of hands with triangulation. We also propose a novel static componnets elimination algorithm for tracking correction by eliminating the components unrelated to motion. A prototype of CentiTrack is fully realized and evaluated in various real scenarios. Extensive experiments show that CentiTrack is superior in terms of tracking accuracy, sensing range, and device cost, compared with the state-of-the-arts.
Gene pyramiding enhances durable blast disease resistance in rice (2015)

Effective control of blast, a devastating fungal disease of rice, would increase and stabilize worldwide food production. Resistance mediated by quantitative trait loci (QTLs), which usually have smaller individual effects than R-genes but confer broad-spectrum or non-race-specific resistance, is a promising alternative to less durable race-specific resistance for crop improvement, yet evidence that validates the impact of QTL combinations (pyramids) on the durability of plant disease resistance has been lacking. Here, we developed near-isogenic experimental lines representing all possible combinations of four QTL alleles from a durably resistant cultivar. These lines enabled us to evaluate the QTLs singly and in combination in a homogeneous genetic background. We present evidence that pyramiding QTL alleles, each controlling a different response to M. oryzae, confers strong, non-race-specific, environmentally stable resistance to blast disease. Our results suggest that this robust defence system provides durable resistance, thus avoiding an evolutionary "arms race" between a crop and its pathogen.
Analysis of Cellular Responses to Native and Recombinant Proteins of Cowdria ruminantiumaa (1998)

The response of PBMC collected from cattle immunized with killed Cowdria to MAP1, MAP1-B, MAP2 and to a lysate of Cowdria was characterized in vitro. CD4+ T lymphocytes responded strongly to Cowdria lysates while B cells and gamma delta T cells proliferated in response to recombinant proteins. Short-term cell lines derived from PBMC using Cowdria lysates were more than 90% CD4+ and did not respond to any of the recombinant proteins. Restimulation of PBMC with MAP1, MAP1-B, and MAP2 proved difficult, and cultures usually stopped proliferating after 2 to 3 weeks. Only one cell line could be generated using MAP1 and it was composed of 85% gamma delta T cells. This study indicates that in animals immunized with killed Cowdria, proteins other than the serologically immunodominant MAP1 and MAP2 are strongly immunogenic for T lymphocytes.
Noncovalent synthesis of organic fibers** (1995)

The self‐assembly of organic molecules into fibers (e.g. see Fig.) is reversible. In the dreams of chemists the exploitation of this phenomenon could lead, for example, to the use of bio‐compatible fibrous organics to simulate blood clots. Dissolution of the clot could be affected thermally or chemically. Recently developed technology which could make this sort of ting possible in the future is reviewed magnified image .
Stereoregular and stereoirregular alternating ethylene-norbornene copolymers (2001)

International audience
Digital radiograph of crush thoracic trauma in the Sichuan earthquake (2011)

Earthquake-related crush thoracic trauma has the potential for multiple fractures. The high number of fractured ribs and pulmonary contusions were significant factors which needed appropriate medical treatment.
Immunity to Glycan α-Gal and Possibilities for the Control of COVID-19 (2020)

Ongoing research focuses on vaccines targeting SARS-CoV-2 for the prevention and control of COVID-19.&#13;\nHowever, boosting the immune response to glycan α-Gal with a broader and not restricted to pathogen-specific&#13;\nimmunity may contribute not only to the control of COVID-19 but also to other pathogens that negatively affect&#13;\nthe individual response to SARS-CoV-2. The COVID-19 pandemic has expanded rapidly worldwide with millions of infected individuals and hundreds of thousands dead patients. Recently, new vaccines are under investigation at different levels for the control of COVID-19. These vaccines are focused on the SARS-CoV-2 by using inactivated or attenuated whole viruses, replicating and nonreplicating vectors, virus-like particles, recombinant proteins and RNA/DNA technologies. However, despite the advances and potential impact that these vaccines represent for the prevention and control of COVID-19, interventions boosting the immune response with a broader and not pathogen-specific immunity may contribute not only to the control of COVID-19 but also to potential reinfections by SARS-CoV-2-related genetic variants or other pathogens that negatively affect the individual response to SARS-CoV-2.
Expanded Porphyrins (2022)

Expanded porphyrins are porphyrin analogues consisting of more than five pyrroles. Among these, meso -aryl-substituted expanded porphyrins have emerged as novel π-conjugated macrocycles in light of their intriguing optical and electrochemical properties, structural diversities, and coordination abilities. Their first one-pot synthesis was developed in 2001, and since then, various modified synthetic protocols have allowed the isolation of unique expanded porphyrin congeners. This chapter summarizes the syntheses and properties of meso -aryl-substituted expanded porphyrins with a particular focus on the relationship between aromaticity and molecular topology. An intriguing feature is that meso -aryl-substituted expanded porphyrins have been shown to serve as a unique platform for realizing Möbius aromatic and antiaromatic molecules upon suitable stimuli such as metal coordination, protonation, and intramolecular fusion reaction. Another attractive attribute is the possibility of realizing giant aromatic molecules with distinct global aromaticities. Large meso -aryl-substituted expanded porphyrins in a neutral state tend to adopt coiled structures due to effective intramolecular hydrogen bonding interactions, but, upon protonation or metalation, their conformations are changed to yield global aromatic networks.
Fabrication of Cross-Linked Polyethyleneimine Microfibers by Reactive Electrospinning with In Situ Photo-Cross-Linking by UV Radiation (2010)

The objective of this work is to demonstrate the feasibility of fabrication of cross-linked polyethyleneimine microfibers by a reactive photo-electrospinning technology. Linear polyethyleneimine (L-PEI) has been grafted with cross-linkable methacrylate moiety by reaction with glycidyl methacrylate (GMA), enabling the polymer to cross-link upon UV exposure. The photo-cross-linking reaction was characterized by a photo-rheometer. Neat L-PEI or methacrylated L-PEI tends to aggregate rendering it very difficult to electrospin into microfibers. A high molecular weight polyvinylpyrrolidone (PVP) is an efficient chain entanglement enhancer for both L-PEI and methacrylated L-PEI and helpful to maintain fibrous structure. An optimized composition consisted of 10% methacrylated L-PEI (less than 14.8% methacrylation of total L-PEI) combined with 2% PVP and 1% photoinitiator in ethanol was successfully electrospun into smooth cross-linked microfibers using the reactive electrospinning device. Diameters of cross-linked fibers can be controlled from 419 nm to 2 μm depending on methacrylation degree and UV irradiation intensity. The resultant cross-linked L-PEI microfibers have demonstrated significantly improved solvent resistance, thermal stability, and mechanical properties. The distinguished characteristics of this novel reactive electrospinning technology are the high cross-linking efficiency and minimal toxic chemical residues in the products. The stability of the fibers can be readily modified and controlled by the cross-linking degree, which is of great importance for biomedical applications.
CD226 and TIGIT Cooperate in the Differentiation and Maturation of Human Tfh Cells (2022)

Costimulation pathways play an essential role in T cell activation, differentiation, and regulation. CD155 expressed on antigen-presenting cells (APCs) interacts with TIGIT, an inhibitory costimulatory molecule, and CD226, an activating costimulatory molecule, on T cells. TIGIT and CD226 are expressed at varying levels depending on the T cell subset and activation state. T follicular helper cells in germinal centers (GC-Tfh) in human tonsils express high TIGIT and low CD226. However, the biological role of the CD155/TIGIT/CD226 axis in human Tfh cell biology has not been elucidated. To address this, we analyzed tonsillar CD4<sup>+</sup> T cell subsets cultured with artificial APCs constitutively expressing CD155. Here we show that CD226 signals promote the early phase of Tfh cell differentiation in humans. CD155 signals promoted the proliferation of naïve CD4<sup>+</sup> T cells and Tfh precursors (pre-Tfh) isolated from human tonsils and upregulated multiple Tfh molecules and decreased IL-2, a cytokine detrimental for Tfh cell differentiation. Blocking CD226 potently inhibited their proliferation and expression of Tfh markers. By contrast, while CD155 signals promoted the proliferation of tonsillar GC-Tfh cells, their proliferation required only weak CD226 signals. Furthermore, attenuating CD226 signals rather increased the expression of CXCR5, ICOS, and IL-21 by CD155-stimulated GC-Tfh cells. Thus, the importance of CD226 signals changes according to the differentiation stage of human Tfh cells and wanes in mature GC-Tfh cells. High TIGIT expression on GC-Tfh may play a role in attenuating the detrimental CD226 signals post GC-Tfh cell maturation.
Cobalt disilicide intercell ohmic contacts for multijunction photovoltaic energy converters (1994)

We have created thin buried films of low resistivity CoSi2 in silicon by ion implantation, and used them to provide intercell ohmic contacts for monolithically stacked multijunction photovoltaic energy converters. We have grown epitaxial silicon pn junction diodes by chemical vapor deposition onto the thin film of crystalline silicon formed over the CoSi2 layer after post-implantation annealing. A single junction photovoltaic device with two CoSi2 contacts displayed an open circuit voltage of 0.60 V and a fill factor of 0.80, while a double junction tandem cell with three CoSi2 interconnects generated 1.2 V, under identical conditions of illumination with a Nd:YAG laser. These results indicate very low defect levels in the deposited silicon epitaxial layers, and excellent functioning of the CoSi2 interconnects.
Structure of Acinetobacter Strain ADP1 Protocatechuate 3,4-Dioxygenase at 2.2 Å Resolution:  Implications for the Mechanism of an Intradiol Dioxygenase (2000)

The crystal structures of protocatechuate 3,4-dioxygenase from the soil bacteria Acinetobacterstrain ADP1 (Ac 3,4-PCD) have been determined in space group I23 at pH 8.5 and 5.75. In addition, the structures of Ac 3,4-PCD complexed with its substrate 3, 4-dihydroxybenzoic acid (PCA), the inhibitor 4-nitrocatechol (4-NC), or cyanide (CN(-)) have been solved using native phases. The overall tertiary and quaternary structures of Ac 3,4-PCD are similar to those of the same enzyme from Pseudomonas putida[Ohlendorf et al. (1994) J. Mol. Biol. 244, 586-608]. At pH 8.5, the catalytic non-heme Fe(3+) is coordinated by two axial ligands, Tyr447(OH) (147beta) and His460(N)(epsilon)(2) (160beta), and three equatorial ligands, Tyr408(OH) (108beta), His462(N)(epsilon)(2) (162beta), and a hydroxide ion (d(Fe-OH) = 1.91 A) in a distorted bipyramidal geometry. At pH 5.75, difference maps suggest a sulfate binds to the Fe(3+) in an equatorial position and the hydroxide is shifted [d(Fe-OH) = 2.3 A] yielding octahedral geometry for the active site Fe(3+). This change in ligation geometry is concomitant with a shift in the optical absorbance spectrum of the enzyme from lambda(max) = 450 nm to lambda(max) = 520 nm. Binding of substrate or 4-NC to the Fe(3+) is bidentate with the axial ligand Tyr447(OH) (147beta) dissociating. The structure of the 4-NC complex supports the view that resonance delocalization of the positive character of the nitrogen prevents substrate activation. The cyanide complex confirms previous work that protocatechuate 3,4-dioxygenases have three coordination sites available for binding by exogenous substrates. A significant conformational change extending away from the active site is seen in all structures when compared to the native enzyme at pH 8.5. This conformational change is discussed in its relevance to enhancing catalysis in protocatechuate 3,4-dioxygenases.
Expression of different vascular endothelial markers in prostate cancer and BPH tissue: an immunohistochemical and clinical evaluation. (2004)

CD34 is a suitable marker for the immunohistochemical visualization of microvessels in benign and malignant prostate tissue.
Metal Forming Aspects of Cyclic Severe Plastic Deformation of Ti-Ni Shape Memory Alloys Using MaxStrain Device (2017)

The effect of severe plastic deformation using MaxStrain ( MS ) device which is a part of the Gleeble thermo-mechanical simulator of rolling and forging processes on the structure and functional properties of Ti–50.0 at.% Ni shape memory alloy has been studied. The use of the MS module allows performing SPD of the material under isothermal conditions with precise control of the deformation parameters. The deformation temperature was lowered from 370 to 330 °C. The accumulated true strain varied from e =4.6 to 9.5. Structure features were studied by the transmission electron microscopy. The maximum completely recoverable strain was determined by a thermomechanical method using a bending mode for strain inducing. A mixed submicrocrystalline and nanosubgrained structure with average grain/subgrain size below 100 nm was formed using SPD at 330 °C. A very high completely reсoverable strain (9.3%) was obtained against a reference treatment (2.5%).
Finitely Convergent Deterministic and Stochastic Iterative Methods for\n Solving Convex Feasibility Problems (2019)

We propose finitely convergent methods for solving convex feasibility\nproblems defined over a possibly infinite pool of constraints. Following other\nworks in this area, we assume that the interior of the solution set is nonempty\nand that certain overrelaxation parameters form a divergent series. We combine\nour methods with a very general class of deterministic control sequences where,\nroughly speaking, we require that sooner or later we encounter a violated\nconstraint if one exists. This requirement is satisfied, in particular, by the\ncyclic, repetitive and remotest set controls. Moreover, it is almost surely\nsatisfied for random controls.\n
Cooperative maximum-ratio transmission with multi-antenna relay nodes for tactical mobile ad-hoc networks (2020)

In this paper, we propose a cooperative maximum-ratio transmission (C-MRT) technique with multi-antenna relay nodes for tactical mobile ad-hoc networks (MANETs) where both the location and the number of antennas of relay nodes are arbitrary. Each relay node is assumed to know both the wireless channel coefficient from the source node to itself and the wireless channel from itself to the destination node, which is known as local channel state information (CSI) assumption. Maximum-ratio combining (MRC) and MRT techniques are used for beamforming the transmit and receive signals of the relay node, respectively. In addition, we mathematically analyze the overall outage probability of the proposed technique with moment generating function (MGF). It is shown that the mathematical analysis on the overall outage probability of the proposed C-MRT technique is matched well with the simulation results especially in high transmit power regimes. It is also observed that the proposed technique outperforms other schemes such as phase steering (PS) and optimal relay selection (ORS) in terms of outage probability.
Supplementary Figure 9 from BET Inhibition Sensitizes Immunologically Cold Rb-Deficient Prostate Cancer to Immune Checkpoint Blockade (2023)

&lt;p&gt;T cell and macrophage depletion studies in mice bearing Myc-CaPWT or Myc-CaPΔRb tumors.&lt;/p&gt;
Bacterial Activity Enhancement and Soil Decontamination (2001)

The prelims comprise: Introduction Physical Property Amendment Nutrient Supplements Cometabolism Bioaugmentation Conclusions
Prepartum nutritional strategy affects reproductive performance in dairy cows (2013)

Negative energy balance during early postpartum is associated with reduced reproductive performance in dairy cows. A pooled statistical analysis of 7 studies completed in our group from 1993 to 2010 was conducted to investigate the association between prepartum energy feeding regimen and reproductive performance. The interval from calving to pregnancy (days to pregnancy, DTP) was the dependent variable to assess reproductive performance. Individual data for 408 cows (354 multiparous and 54 primiparous) were included in the analysis. The net energy for lactation (NEL) intake was determined from each cow's average dry matter intake and calculated dietary NEL density. Treatments applied prepartum were classified as either controlled-energy (CE; limited NEL intake to ≤100% of requirement) or high-energy (HE; cows were allowed to consume >100%) diets fed during the far-off (FO) or close-up (CU) dry periods. Cow was the experimental unit. The Cox proportional hazard model revealed that days to pregnancy was shorter for CE (median=157 d) than HE (median=167 d) diets during the CU period [hazard ratio (HR)=0.70]. Cows fed HE diets during the last 4 wk prepartum lost more body condition score in the first 6 wk postpartum than those fed CE diets (-0.43 and -0.30, respectively). Cows fed CE diets during the FO period had lower nonesterified fatty acids concentrations in wk 1, 2, and 3 of lactation than cows fed HE diets. Higher nonesterified fatty acids concentration in wk 1 postpartum was associated with a greater probability of disease (n=251; odds ratio=1.18). Cows on the CE regimen during the FO period had greater plasma glucose concentrations during wk 1 and 3 after calving than cows fed the HE regimen. Higher plasma glucose (HG) concentration compared with lower glucose (LG) in wk 3 (HG: n=154; LG: n=206) and wk 4 (HG: n=71; LG: n=254) after calving was associated with shorter days to pregnancy (wk 3: median=151 and 171 d for HG and LG, respectively, and HR=1.3; wk 4: median=148 and 167 d, respectively, and HR=1.4). In the first 2 wk after calving, cows that received HE diets in the FO period had higher concentrations of total lipids and triglyceride and greater ratio of triglyceride to glycogen in liver than cows fed CE diets. In conclusion, cows fed CE diets during the CU period had a shorter interval between parturition and conception, which may be explained by increased NEL intake during the first 4 wk postpartum and lower incidence of peripartal diseases. Lower body condition score loss during the first 6 wk postpartum and slightly higher glucose concentration at wk 3 likely contributed to improved reproductive performance.
A New Conformational Search Technique and Its Applications (2006)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Stabilization in a chemostat with sampled and delayed measurements (2016)

We study chemostat models with constant substrate input concentrations. We allow growth functions that are not necessarily monotone. The measurement is the substrate concentration, which is piecewise constant with a nonconstant delay, so only sampled observations are available. Under new conditions on the size of the delay and on the largest sampling interval, we solve the problem of asymptotically stabilizing a componentwise positive equilibrium point with the dilution rate as the control. We use a new Lyapunov approach.
Turn the Next Page (2020)

Contemporary research has enriched our knowledge of mechanisms involved in the generation and persistence of the debilitating disorders characterized by an “addictive dimensionality,” such as substance use disorders and binge eating disorder. Personalized treatment strategies for addictive disorders might include one or a combination of medications at important stages in detoxification and recovery to reduce craving, assist in establishing a substance-free state, and open the optimal window to allow cognitive restructuring and enhanced inhibitory control of substance-seeking. The overlapping neural systems and brain circuitry involved across addictive disorders have elevated interest in the metabolic and neural regulators serotonin (5-hydroxytryptamine; 5-HT) and ghrelin. This chapter focuses on these systems as examples of how we can broaden our horizons for advancing future therapeutic and biomarker initiatives.