gebhart/patrepeval huggingface dataset:
An Architecture for Integrated Intelligence in Urban Management Using Cloud Computing (2011)

With the emergence of new methodologies and technologies it has now become possible to manage large amounts of environmental sensing data and apply new integrated computing models to acquire information intelligence. This paper advocates the application of cloud capacity to support the information, communication and decision making needs of a wide variety of stakeholders in the complex business of the management of urban and regional development. The complexity lies in the interactions and impacts embodied in the concept of the urban-ecosystem at various governance levels. This highlights the need for more effective integrated environmental management systems. This paper offers a user-orientated approach based on requirements for an effective management of the urban-ecosystem and the potential contributions that can be supported by the cloud computing community. Furthermore, the commonality of the influence of the drivers of change at the urban level offers the opportunity for the cloud computing community to develop generic solutions that can serve the needs of hundreds of cities from Europe and indeed globally.
SIMULTANEOUS CONFIDENCE REGIONS IN AN EXTENDED GROWTH CURVE MODEL WITHkHIERARCHICAL WITHIN-INDIVIDUALS DESIGN MATRICES (2002)

ABSTRACT We consider an extended growth curve model with k hierarchical within-individuals design matrices. The model includes the one whose mean structure consists of polynomial growth curves with k different degrees. First we propose certain simple estimators of the mean and covariance parameters which are closely related to the MLE's. Using these estimators we construct simultaneous confidence regions for each or all of k growth curves which is an extension of Fujikoshi.[2] Fujikoshi, Y. 1999. Simultaneous Confidence Intervals in an Extended Growth Curves. Commun. Statist.–-Theor. Meth., 28: 671–682. [Taylor & Francis Online], [Web of Science ®] , [Google Scholar] A numerical example with k = 3 is also given.
Endothelin-Converting Enzyme Expression in the Rat Vascular Injury Model and Human Coronary Atherosclerosis (1997)

The present study ascertained that ECE-1 is expressed in neointimal smooth muscle cells in rat balloon-injured arteries and in both smooth muscle cells and macrophages in human coronary atherosclerotic lesions. Blockade of ECE-1 was effective in reducing neointimal formation after balloon injury. Thus, ECE-1 may contribute to the process of injury-induced neointimal formation and atherosclerosis through the autocrine/paracrine effects of endothelin 1.
Distributed &amp; adaptive HTTP streaming (2011)

Adaptive streaming with HTTP has become popular in recent years, enabling continuous delivery of live and VOD content without the need for guaranteed bandwidth. It remains however challenging to maintain a smooth quality of experience under tough network conditions especially for bandwidth eater content like High Definition or 3D. In this paper we show that it is possible to both greatly improve the average quality and attenuate the quality variations for a better user experience by leveraging multipath communication requiring no extra bandwidth. We exploit concurrently multiple paths using a CDN compliant distributed streaming infrastructure and standard HTTP range requests and present the results of several network configurations.
ChemInform Abstract: CHEMIE DER PILZE 65. MITT. STRUKTUREN VON ERGOCHRYSIN A, ISOERGOCHRYSIN A, ERGOXANTHIN UND DEN SECALONSAEUREN A, B, C UND D (1972)

Abstract Im Zusammenhang mit den im Titel erwähnten Strukturaufklärungen werden eine Anzahl Biphenyle synthetisiert.
Collaborative Environment with Visualizing Medical Volume Data by Virtual Reality (2007)

We have developed a virtual reality collaborative environment on volume communications environment, which is a tele-immersive collaboration environment on a grid infrastructure. The system is targeted to develop this tools; it is an integrated environment consisting of a real time information sharing system between remotely located researchers and a three-dimensional (3D) image-based real-time communication system. To evaluate the system's functionality and performance, we have used it for real research problems, in the medical areas. This paper describes the system and effectiveness of virtual reality.
oTal synthesis of two furanomycin stereoisomers (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXToTal synthesis of two furanomycin stereoisomersShin Yih Chen and Madeleine M. JoullieCite this: J. Org. Chem. 1984, 49, 10, 1769–1772Publication Date (Print):May 1, 1984Publication History Published online1 May 2002Published inissue 1 May 1984https://pubs.acs.org/doi/10.1021/jo00184a020https://doi.org/10.1021/jo00184a020research-articleACS PublicationsRequest reuse permissionsArticle Views216Altmetric-Citations27LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Convolutional neural networks at constrained time cost (2015)

Though recent advanced convolutional neural networks (CNNs) have been improving the image recognition accuracy, the models are getting more complex and time-consuming. For real-world applications in industrial and commercial scenarios, engineers and developers are often faced with the requirement of constrained time budget. In this paper, we investigate the accuracy of CNNs under constrained time cost. Under this constraint, the designs of the network architectures should exhibit as trade-offs among the factors like depth, numbers of filters, filter sizes, etc. With a series of controlled comparisons, we progressively modify a baseline model while preserving its time complexity. This is also helpful for understanding the importance of the factors in network designs. We present an architecture that achieves very competitive accuracy in the ImageNet dataset (11.8% top-5 error, 10-view test), yet is 20% faster than “AlexNet” [14] (16.0% top-5 error, 10-view test).
Seafood Health Facts: Communicating the Benefits and Risks for Health Care Providers and Patients (2012)

"Seafood Health Facts: Communicating the Benefits and Risks for Health Care Providers and Patients." Journal of Aquatic Food Product Technology, 21(2), pp. 97–98
P08.06: Results of 22q11.2 microdeletion using FISH technique, in 110 fetuses with congenital heart disease (2011)

The 22q11.2 deletion is a common chromosomal deletion syndrome, with a postnatal prevalence of 1 : 4000 newborns, with dominant autosomical inherited and with a wide phenotypical and clinical variability, which includes Velo-Cardio-Facial syndrome (VCFS/del 22q11), DiGeorge syndrome, Shprintzen, Takao (conotruncal anomaly face syndrome) and Cayler syndrome. The diagnose of this disease is important because it is a multisystemic disease that has different clinical expressions: congenital heart disease (conotruncal defect the most frequent), immunological abnormalities (cellular immunity) endocrynological abnormalities, palate/facial defects, dysmorphies, skeletal and neurological abnormalities. The prenatal prevalence it is probably more elevated than the postnatal prevalence, with a described prevalence of 1.6–11.5% in some series. The aim of our study is to present our experience in prenatal diagnose, using the in situ hybridization (FISH technique) of fetuses with congenital heart disease (CHD). We studied 110 fetuses with a CHD using FISH technique (Tuple I probe, 22q13 marker, Vysis), by the analysis of cultivated corial velocities (3 cases), cultivated amniotic fluid (61 cases), non-cultivated amniotic fluid (37 cases) and fetal blood (9 cases). We detect the critical deletion zone of DiGeorge and velocardiofacial syndrome in 4 fetuses (it represents a prevalence of 4%), which all of them were de novo mutations. In situ hybridization (FISH technique), is a pretty good method for the diagnose of 22q11.2 deletion in different fetal tissues. As in other series, our prenatal prevalence is much more elevated than the postnatal prevalence.
Raptor Codes for Infrastructure-to-Vehicular Broadcast Services (2011)

One of the important applications to be available in vehicular ad-hoc networks are value-added or infotainment services. However, vehicular communication suffers from high packet loss due to challenging channel characteristics such as huge Doppler spread and multipath fading. This makes current IEEE 802.11p standard for vehicular network based on the ARQ scheme inefficient. Therefore, the highly scalable and fault-tolerant properties offered by rateless code makes this a promising area of research. This paper investigates the implementation of a systematic Raptor codes for a broadcast service in infrastructure-to-vehicular communications. The code performance in terms of the decoding probability of success, mean decoding time and mean aggregate throughput are presented.
Raman and TEM studies of Ge nanocrystal formation in SiOx:Ge/SiOx multilayers (2007)

Abstract Alternating germanosilicate‐siliconoxide layers of 10‐30 nm thickness were grown on Si substrates by plasma enhanced chemically vapor deposition (PECVD). The compositions of the grown films were determined by X‐ray photoelectron spectroscopy measurements. The films were annealed at temperatures varying from 670 to 1000 °C for 5 to 45 minutes under nitrogen atmosphere. High resolution cross section TEM images, electron diffraction and electron energy‐loss spectroscopy as well as energy‐dispersive X‐ray analysis (EDAX) data confirm presence of Ge nanocrystals in each layer. The effect of annealing on the Ge nanocrystal formation in multilayers was investigated by Raman spectroscopy and Transmission Electron Microscopy (TEM). As the annealing temperature is raised to 850 °C, single layer of Ge nanocrystals observed at lower annealing temperatures is transformed into a double layer with the smaller sized nanocrystals closer to the substrate SiO 2 interface. (© 2007 WILEY‐VCH Verlag GmbH &amp; Co. KGaA, Weinheim)
The role ofClock in the developmental expression of neuropeptides in the suprachiasmatic nucleus (2000)

The suprachiasmatic nucleus (SCN) is the dominant circadian pacemaker in mammals. To understand better the ontogeny of mouse SCN and the role of the pacemaker in peptide expression, the authors examined the distribution of cells that were immunoreactive for vasopressin (AVP) or vasoactive intestinal polypeptide (VIP) in wild type and Clock mutant mice at two developmental stages. Clock homozygous mice failed to show the dramatic increase in the number of VIP-immunoreactive (VIP-ir) neurons from postnatal day 6 (P6) to P30 that was found in the SCN of wild type mice. The number of AVP-ir neurons was relatively constant in the postnatal SCN but was significantly reduced in Clock/Clock mice. The effects of the Clock mutation varied with position in the SCN for both peptides. Densitometry of immunolabeled brains indicated that the Clock mutation reduced AVP expression specifically in the SCN and not in other brain areas. The SCN did not significantly change shape or size with age or Clock genotype. Taken together, these results indicate that the neonatal mouse SCN has its full complement of cells, some of which are not yet mature in their neuropeptide content. Furthermore, the observation that the Clock mutation appears to act on a subset of AVP and VIP cells suggests heterogeneity within these cell classes in the SCN.
Blockade of receptor activator of nuclear factor‐κB signaling greatly improves SERCA activity and contractility in atrophic and dystrophic skeletal muscles (731.7) (2014)

Receptor‐activator of nuclear factor‐κB (RANK), its ligand RANKL and the soluble decoy receptor osteoprotegerin (OPG) are members of the tumor necrosis factor (TNF) superfamily that control osteoclast differentiation, bone remodelling and osteoporosis. Since bone and skeletal muscle physiopathology occurs synchronously, we tested whether RANK/RANKL pathway is involved in muscle dysfunction following different muscle wasting conditions. Contractile properties of EDL muscles were obtained following 14d of denervation in mice specifically deficient in RANK skeletal muscle or in dystrophic mdx mice treated daily for 10d with OPG [0.3mg/kg], the natural inhibitor of RANKL. The activity and expression of sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) were determined in denervated or dystrophic muscles. RANK muscle deletion did not prevent atrophy but greatly reduced the losses of force production and SERCA activity in denervated EDL muscles. Force production of EDL muscles also increased by 140% in OPG‐treated relative to PBS‐treated mdx mice while the treatment with OPG prevented the loss of the fast twitch SERCA1 protein content in dystrophic mice. Together, these data indicate that the deletion or blockage of RANK/RANKL pathway has inotropic effects and increases SERCA activity and expression in fast‐twitch skeletal muscles opening promising new avenues for several muscle diseases.
Binding the low affinity Fc epsilon R on B cells suppresses ongoing human IgE synthesis. (1989)

Our results support the hypothesis that binding the low affinity Fc epsilon R (Fc epsilon R-II, CD23) on IgE-secreting B cells, directly suppresses IgE production. IgE production from AF-10/U266 (a human IgE plasmacytoma) decreased upon incubation with anti-IgE mAb or IgE:anti-IgE immune complexes (IgE-IC). Synthesis was suppressed a maximum of 51% with 10 micrograms/ml of IgE-IC after a 24-h incubation. Spontaneous in vitro IgE synthesis from the B cells of highly atopic individuals was also inhibited in a similar fashion. This effect was isotype specific as IgA or IgG immune complexes did not alter IgE production from AF-10 nor did IgE-IC affect IgA or IgG synthesis from lymphoblastoid cell lines making IgG (GM1500 and RPMI 8866) or IgA (GM1056). U266/AF-10 cells displayed both membrane IgE (greater than 90%) and Fc epsilon R-II (23%). To evaluate the role of these membrane proteins in the observed suppression of IgE synthesis, we treated U266/AF-10 cells with IgE-IC that bound Fc epsilon R-II but could not bind membrane IgE, as the mAb used was directed against an idiotypic determinant on the myeloma IgE (PS) used to make the IgE-IC. Suppression was maximal (greater than 50%) with these complexes at 0.1 micrograms/ml and at a 1/1 ratio of mAb anti-IgE to human myeloma IgE. When IgE-IC were used that were constructed with heat denatured IgE or F(ab')2 fragments of IgE, suppression was abrogated indicating IgE-Fc epsilon R binding was required. Neither PS IgE nor mAb 5.1 (the components of IgE-IC) alone affected IgE synthesis. Furthermore, a mAb binding directly to CD23 suppressed IgE synthesis from AF-10 up to 60%. Using limiting dilution analysis, we determined that IgE production per AF-10 cell was constant (0.9 pg/cell/24 h), independent of cell density and cells incubated with IgE-IC were uniformly suppressed. To clarify the mechanism of IgE-IC-induced suppression on AF-10 cells, we assessed both the proliferative rate and cell cycle distribution upon incubation with IgE-IC. There was no correlation between IgE production and [3H]TdR incorporation by AF-10 cells incubated with IgE-IC or anti-CD23 mAb. The distribution of cells within the cell cycle was unaffected by these treatments, with 60% of the cells in G1. These results define a direct role for the Fc epsilon R-II on B cells in the regulation of ongoing IgE synthesis.
Itraconazole pulse therapy vs continuous terbinafine dosing for toenail onychomycosis. (1999)

In this open, randomized, parallel-group, the efficacy and safety of itraconazole pulse therapy (1 week 400 mg daily, 3 months) was evaluated in comparison with continuous terbinafine dosing (250 mg daily, 3 months) for the treatment of toenail onychomycosis. The study included a total of 51 patients with distal subungual onychomycosis of the toenails confirmed by microscopy and positive culture. Twenty-six patients received itraconazole pulse therapy and 25 patients received continuous terbinafine therapy. A minimum of 50% nail involvement was a requirement for inclusion. In total, 153 nails (121 toenails) were treated with itraconazole pulse therapy and 162 nails (122 toenails) were treated with continuous terbinafine therapy. Patients were evaluated every third month for 9 months after treatment. Photographs were taken at each visit. Clinical success and mycologic cure (negative potassium hydroxide preparation and culture) were the main outcome measures. Mycologic cure rates were 75% in the itraconazole pulse group and 76% in the continuous terbinafine group at month 12; the corresponding clinical response rates were 77% and 68%, respectively. Six (23%) patients in the itraconazole group reported 7 adverse events and 13 (52%) patients in the terbinafine group reported 19 adverse events. In the terbinafine group, 12% discontinued therapy due to adverse events; no patients in the itraconazole arm discontinued. Both therapies showed comparable efficacy, though baseline nail severity was greater in the itraconazole group, and adverse effects were greater in the terbinafine group.
Eliminating the Rugosity Effect From Compensated Density Logs by Geometrical Response Matching (1991)

Summary A theoretical and experimental effort to understand the effects of borehole rugosity on individual detector responses yielded an improved method of processing compensated density logs. Historically, the spine/ribs technique for obtaining borehole and mudcake compensation of dual-detector, gamma-gamma density logs has been very successful as long as the borehole and other environmental effects vary slowly with depth and the interest is limited to vertical features broader than several feet. With the increased interest in higher vertical resolution, a more detailed analysis of the effect of such quickly varying environmental effects as rugosity was required. A laboratory setup simulating the effect of rugosity on Schlumberger Litho-DensitySM tools (LDT) was used to study vertical response functions. These functions were used to derive matching filters, enabling a significant improvement in the compensated log response in the presence of rugosity. The data served as a benchmark for the Monte Carlo models used to generate synthetic density logs in the presence of more complex rugosity patterns. The results show that proper matching of the two detector responses before application of conventional compensation methods can eliminate rugosity effects without degrading the measurement's vertical resolution. The accuracy of the results is as good as that obtained in a parallel mudcake or standoff with the conventional method. Application to both field and synthetic logs confirmed the validity of these results.
Anterior Cruciate Ligament Tear Prevention in the Female Athlete (2005)

This paper examines the effectiveness of implementing neuromuscular and proprioceptive training programs in female athletes and their ability to decrease the incidence of anterior cruciate ligament (ACL) injury. The relationship of sex, age, and training on the incidence of ACL injury is pivotal in developing a comprehensive neuromuscular and proprioceptive training program to decrease ACL injuries occurring in female athletes. Based on the 2-year results, ACL incidence has remained consistently lower in the intervention group versus the control group. A prophylactic neuromuscular and proprioceptive training program may have a direct benefit in decreasing the number of ACL injuries incurred by female athletes. This research foundation endorses further epidemiologic and biomechanic studies to determine the exact mechanism of ACL injury and the most effective intervention that will effectively decrease ACL injuries in this high-risk population.
The unexplored void of ADHD and African-American research: A review of the literature (1997)

Objective: To identify the body of knowledge exploring the subject of ADHD and African- Americans. Method: A systematic review of the literature was conducted through the Medline, Psychlit and Psychlnfo databases. Results: In contrast to thousands of articles on ADHD, only 16 articles were identified that dealt with ADHD in African-American youth. Additionally, only a handful of these articles had ethnicity as the primary focus of research. Studies that examined ADHD among African-Americans in a school context showed that race may affect how teachers diagnose hyperactivity. Treatment studies suggested that African-Americans may respond similarly to the same ADHD medications as do Caucasians. Studies evaluating ADHD assessment tools were so sparse that they were largely inconclusive. Discussion: The paucity of studies on the subject of ADHD and African-Americans suggests the urgent need for more research to be done in this area. Such studies should be based on culturally sensitive designs.
On the transient response of the turbulent boundary layer inception in compressible flows (2018)

The behavioural characteristics of thermal boundary layer inception dictate the efficiency of heat exchangers and the operational limits of fluid machinery. The specific time required by the thermal boundary layer to be established is vital to optimize flow control strategies, as well as the thermal management of systems exposed to ephemeral phenomena, typically on the millisecond scale. This paper presents the time characterization of the momentum and thermal boundary layer development in transient turbulent compressible air flows. We present a new framework to perform such estimations based on detailed unsteady Reynolds averaged Navier–Stokes simulations that may be extended to higher fidelity simulations. First of all, the aerodynamic boundary layer initiation is described using adiabatic simulations. Additional numerical calculations were then performed by setting the isothermal wall condition to evaluate the additional time required by the thermal boundary layer to establish after the aerodynamic boundary layer reaches its steady state. Finally, full conjugate simulations were executed to compute the warm up effect of the solid during the blowdown of a hot fluid over a colder metallic test model. The transient performance of the turbulent thermal and momentum boundary layers is quantified through numerical simulations of air blowdown over a flat plate for different mainstream flow conditions. The effects of Reynolds number, free stream velocity, transient duration, test article length and free stream temperature were independently assessed, to then define a mathematical expression of the momentum boundary layer settlement. This paper presents a novel numerical correlation of the additional time required by the thermal boundary layer to be stablished after the settlement of the momentum boundary layer. The time scales of the aerodynamic and thermal boundary layers are presented as a function of relevant non-dimensional numbers, as well as the description of the response of the near wall flow to sudden free stream changes. The characterization of the boundary layer mechanisms discussed in this paper contribute to the establishment of an evidence-based foundation for advances in the field of flow control.