gebhart/patrepeval huggingface dataset:
Influence of the sumastructure on the peri‐implant tissue; in beagle dogs (1995)

The purpose of this study was to compare clinical, radiographic and histological differences around titanium oral implants loaded with either acrylic-veneered metal or ceramo-metal fixed prostheses. Five beagle dogs were used in this investigation. At the beginning of the study, all mandibular premolars and first molars were extracted. After 3 months of healing, 2 Brånemark implants were installed on each side of the mandibles. Three months later, abutments were inserted on each implant and a daily oral hygiene regime was initiated. One month after abutment connection, the implants on one side of the mandible were restored with an acrylic-veneered metal fixed prosthesis, whereas, on the other side a ceramo-metal fixed prosthesis was inserted. The prostheses were constructed in occlusion with the maxillary first molars. The following clinical parameters were measured around each implant at this time (i.e., baseline), and thereafter, at monthly intervals up to 5 months: Plaque Index; Gingival Index; implant mobility (using the Periotest); probing depth and clinical attachment level (using the Florida Probe). In addition, standardized radiographs were taken at baseline and 5 months after insertion of the prostheses and evaluated by subtraction radiography. Another Brånemark fixture was installed on each side of the mandibles 3 months before the end of the study. These implants remained unloaded and submerged for the entire study period. Five months after prosthesis insertion, the animals were killed, and implants with their supporting peri-implant tissues were processed for histological evaluation. Analyses of the clinical, radiographic and histometric parameters revealed no significant differences between the acrylic-veneered and ceramometal loaded implants.(ABSTRACT TRUNCATED AT 250 WORDS)
Crystal Structure and Diffusion Path in the Fast Lithium-Ion Conductor La0.62Li0.16TiO3 (2005)

We report the results of a neutron powder diffraction study of the La(0.62)Li(0.16)TiO3 perovskite that determined the diffusion path of lithium cations at room temperature. At 77 K, the Li cations are located at the 2c site (Wycoff notation of the Cmmm space group) on the (002) La deficient layer, while, at room temperature, they are spread over a wide area and migrate following the 2c-4f-2c or 2c-2d-2c tie line on the (002) layer. The probability density of Li cations has a minimum between the 2c and 4f or between the 2c and 2d positions on the diffusion path in contrast to the previous reports where the bottleneck has been thought to be located at the 2c, 2d, and 4f positions. On the basis of the present structural model, the Li-cation conductivity is discussed in terms of a two-dimensional bond-percolation model for Li-cation diffusion. It was found that the vacancy at the La site is essential for the Li-cation conduction.
Vascular response to short-term systemic hypoxia, hypercapnia, and asphyxia in the cat (1976)

Acute systemic hypoxia, hypercapnia, or asphyxia was produced in ketamine-anesthetized, paralyzed cats by ventilating them for 2-4 min with appropriate gas mixtures. A sustained rise in arterial pressure occurred in all cases. Vascular responses to hypoxia (7% O2, 10% 02, or 14% O2) included muscle constriction, cutaneous (hindpaw) dilatation (no change with 14% O2), renal constriction (unchanged flow), and unchanged intestinal resistance. Asphyxia (hypoxia + 10% CO2) produced a similar pattern, except that intestinal dilatation occurred. Hypercapnia (10% CO2 + 21% O2) produced muscle constriction, renal constriction (unchanged flow), intestinal dilatation, and no change in cutaneous resistance. Intestinal dilatation seemed in all cases a response to elevated CO2 only. Hypercapnia augmented the effects of hypoxia in skin and skeletal muscle. The variation of responses in different vascular beds suggests a patterning of sympathetic discharge, and varying responsivity to local and humoral factors.
Dimensionen des Handels in rezenten Stammeskulturen: Enthographische Beispiele aus Neuguinea (2016)

[nicht vorhanden / not available]
TCAD simulation of the co-implantation species C, F, and N in MOS transistors (2012)

The optimization of advanced CMOS nodes below 65nm requires stringent control of both the lateral and vertical diffusion of the source/drain. One way to control this diffusion is to use co-implant species such as Carbon, Fluorine, and Nitrogen with the standard dopants (Boron, Phosphorus, and Arsenic). The role played by the co-implant species is to reduce dopant transient enhanced diffusion (TED), which is caused by the large number of interstitials generated during ion implantation. Although the mechanisms responsible for controlling TED are well understood, the modeling of such mechanisms in a continuum TCAD simulator remains a challenge. We shall first review the current physical understanding behind TED reduction by the co-implant species. Subsequently, we shall show how this can be implemented in a continuum simulator. Afterward, we will present a set of models capable not only of reproducing experimental data based on SIMS measurements, but can also be used in the simulation of 2D and 3D MOS transistors. The models are based on the trapping of interstitials by the co-implant species and their complexes. The evolution of these complexes will affect the diffusion and activation of the doping species and the shape of the final source/drain junction profiles.
Exhaust Air Dust Monitoring is Superior to Soiled Bedding Sentinels for the Detection of Pasteurella pneumotropica in Individually Ventilated Cage Systems. (2016)

Reliable detection of unwanted organisms is essential for meaningful health monitoring in experimental animal facilities. Currently, most rodents are housed in IVC systems, which prevent the aerogenic transmission of pathogens between cages. Typically soiled-bedding sentinels (SBS) exposed to soiled bedding collected from a population of animals within an IVC rack are tested as representatives, but infectious agents often go undetected due to inefficient transmission. Pasteurellaceae are among the most prevalent bacterial pathogens isolated from experimental mice, and the failure of SBS to detect these bacteria is well established. In this study, we investigated whether analysis of exhaust air dust (EAD) samples by using a sensitive and specific real-time PCR assay is superior to conventional SBS monitoring for the detection of Pasteurella pneumotropica (Pp) infections. In a rack with a known prevalence of Pp-positive mice, weekly EAD sampling was compared with the classic SBS method over 3 mo. In 6 rounds of testing, with a prevalence of 5 infected mice in each of 7 cages in a rack of 63 cages, EAD PCR detected Pp at every weekly time point; SBS failed to detect Pp in all cases. The minimal prevalence of Pp-infected mice required to obtain a reliable positive result by EAD PCR testing was determined to be 1 in 63 cages. Reliable detection of Pp was achieved after only 1 wk of exposure. Analysis of EAD samples by real-time PCR assay provides a sensitive, simple, and reliable approach for Pp identification in laboratory mice.
Initial Treatment of Pediatric Graves' Disease with Methimazole: A Retrospective Follow-up Study (2010)

Antithyroid drugs are widely used in the therapy of Graves' disease (GD), and methimazole (MMI) is preferred for treatment of pediatric GD. The recommended initial dosage of MMI is 0.5-1.0 mg/kg/d for pediatric GD, although there are few studies on the optimal MMI dosage for initial treatment in children. We retrospectively compared the efficacy of different doses of MMI in 35 children with GD. Eight children were excluded due to lack of follow-up, etc. The remaining 27 children were divided into a high-dose group (HD; MMI≥0.7 (0.85 ± 0.13) mg/kg/d, n=8) and a low-dose group (LD; MMI<0.7 (0.51 ± 0.12) mg/kg/d, n=19), and we compared the time needed for the serum FT4 levels to normalize (≤1.6 ng/dl) between the groups. There were no significant differences between the FT4 levels (HD: 5.5 ± 2.8 ng/dl; LD: 5.0 ± 2.4 ng/dl p=0.59) or thyroid stimulating hormone receptor antibody levels (HD: 56.2 ± 29.3%; LD: 60.9 ± 27.2% p=0.69) between the groups before treatment. The mean time required to normalize the FT4 levels was 22.5 ± 7.4 d in the HD group and 28.8 ± 16.2 d in the LD group (p=0.30). In addition, no other factor influenced the time to efficacy of MMI. A dose of MMI<0.7 (0.51 ± 0.12) mg/kg/d appears to as effective as a higher dose in normalizing the serum FT4 level in children with mild or moderate GD.
Prospective SARS-CoV-2 cohort study among general practitioners during the second COVID-19 wave in Flanders, Belgium (2021)

Abstract Primary health care providers (PHCPs), especially general practitioners (GPs) are essential to organise health care efficiently. During the COVID-19 pandemic, they also keep the pressure off hospitals. PHCPs are assumed to be at high risk of a COVID-19 infection, as they are exposed to a large portion of the population (usually with less personal protective equipment than other frontline health care workers(HCWs)). Nevertheless, previous seroprevalence studies focussed on the general population or HCWs in hospital settings, rather than PHCPs. The aim of this study was to determine the seroprevalence of PHCPs after the first and during the second SARS-CoV-2 wave in Flanders (Belgium) and compare it to the seroprevalence in the general population (blood donors). A prospective cohort of PHCPs, mainly GPs ( n =698) was screened for IgG antibodies against SARS-CoV-2 at five different time-points (June-December 2020). The dried blood spots they produced were analysed using a Luminex multiplex immunoassay. The seroprevalence of PHCPs remained stable between June and September 2020 (4.6-5.0%), but increased significantly from October to December (8.1-13.4%) 2020. The seroprevalence of PHCPs was not significantly higher than the seroprevalence of the blood donors at the end of December 2020. In conclusion, the sharp increase in seroprevalence during the second COVID-19 wave in Flanders shows that PHCPs were more at risk during the second wave compared to the first one. However, the increase was in line with the general population suggesting that PHCPs mainly got infected in their private settings.
Shortest Path Homography-Based Visual Control for Differential Drive Robots (2007)

We have presented a new homography-based approach for visual control of mobile robots. The control design is directly based on the homography elements and deals with the motion constraints of the di erential drive vehicle. In our approach, called Shortest Path Control, the motion is designed to follow a straight line path. Taking advantage of this speciï¬c trajectory we have proposed a control law decoupling rotation and translation. Three di erent methods have been designed by choosing di erent homography elements. Their performance depends on the conditions of the plane or the calibration. The methods use neither the homography decomposition nor any measure of the 3D scene. Simulations shows the performance of the methods with odometry drift, image noise and calibration errors. Also, the inï¬‚uence of the plane that generates the homography is studied.
Interactions of a bacterial RND transporter with a transmembrane small protein in a lipid environment (2019)

Abstract The small protein AcrZ in Escherichia coli interacts with the transmembrane portion of the multidrug efflux pump AcrB and increases the resistance of the bacterium to a subset of the antibiotic substrates of that transporter. It is not clear how the physical association of the two proteins selectively changes activity of the pump for defined substrates. Here, we report cryo-EM structures of AcrB and the AcrBZ complex in lipid environments, and comparisons suggest that conformational changes occur in the drug binding pocket as a result of AcrZ binding. Simulations indicate that cardiolipin preferentially interacts with the AcrBZ complex, due to increased contact surface, and we observe that the drug sensitivity of bacteria lacking AcrZ is exacerbated when combined with cardiolipin deficiency. Taken together, the data suggest that AcrZ and lipid cooperate to allosterically modulate the activity of AcrB. This mode of regulation by a small protein and lipid may occur for other membrane proteins.
Cross-reactive potential of rabbit antibodies raised against a cyclic peptide representing a chimeric V3 loop of HIV-1 gp120 studied by biosensor technique and ELISA (1994)

Rabbit antibodies were induced against a free cyclic peptide representing the chimeric sequence of a consensus V3 loop of HIV-1 gp120. The reactivity of these antibodies was tested in a biosensor system (BIAcore, Pharmacia AB, Uppsala, Sweden) and in ELISA with the peptide immunogen in its cyclic and linear forms, as well as with peptides corresponding to the V3 region of different HIV-1 variants. The antibodies reacted with all the peptides tested both in ELISA and in biosensor assays and recognized the cyclic form of the chimeric peptide better than the linear form. Although antibodies raised against the V3 region of particular HIV-1 variants cross-react with other HIV-1 strains, it seems that the use of a chimeric peptide as immunogen improved the cross-reactivity spectrum of recognition of the antibodies. The anti-V3 antibodies were also tested for their ability to neutralize in vitro four HIV-1 laboratory strains. Only the HIVMN variant was found to be neutralized. Compared to conventional solid phase immunoassays, the BIAcore presents several advantages for measuring the differential reactivity of peptide analogues. In view of their broadly cross-reactive potential, antibodies raised against a consensus sequence should be useful in immunodiagnosis of viral antigenic variants.
THE ACTION OF Co60 GAMMA RAYS AND OF FENTON'S REAGENT ON AQUEOUS BROMAL HYDRATE SOLUTIONS (1957)

Aqueous bromal hydrate solutions have been irradiated with Co 60 gamma rays and the production of acid measured. The effect of bromal hydrate concentration, dose rate, pH, and temperature upon the yield of acid has been determined. Major products of the radiolysis have been identified and are compared with those formed when aqueous bromal hydrate solutions are treated with Fenton's reagent, a mixture of hydrogen peroxide and ferrous sulphate solutions. It has been shown that Fenton's reagent will initiate a chain reaction in aqueous bromal hydrate solutions which produces hydrobromic acid.
Selective Service: Right to Counsel, Due Process And The First Amendment (1968)

The leopard gecko is a crepuscular and insectivorous reptile. The role of the tongue in this reptile is fundamental for the prey capture and ingestion and is not related with eyes cleaning as usual in other geckos. The elongated tongue can be divided into a foretongue with a slightly bifurcated apex and a hindtongue. Scanning electron microscopy demonstrated that several different papillae are present on the dorsal surface, foliate and dome-shaped in the foretongue, becoming thicker and stouter with reduced interpapillary spaces in the lateral parts. The hindtongue is characterised by wide foliate papillae with indented margins and deep fissures of the mucosa. Light microscopy showed the presence of a stratified slightly keratinized squamous epithelium in the apex of the foretongue, a stratified non-keratinized squamous epithelium in the fore and in the hindtongue. In the foretongue, numerous muciparous caliciform cells were observed. Moreover, the presence of taste buds on the tongue ventral surface was demonstrated for the first time in this species and the confocal laser study revealed a strong immunoreactivity for the S-100 protein in the sensory cells. Therefore, the results obtained could give a contribution to the knowledge of the tongue anatomy and are a basis for eventual further studies regarding the feeding habits in a reptile become a popular pet.
An Efficient ARQ Scheme with SNR Feedback (2008)

We consider the problem of transmission over an unknown time-varying Gaussian channel, whose signal-to-noise ratio (SNR) is constant within a block but varies arbitrarily between blocks. For this scenario, we develop efficient automatic repeat request (ARQ) protocols in the form of low-complexity rateless codes, which encode a message into a sequence of incremental redundancy blocks. Following the receipt of each redundancy block, the receiver feeds back to the transmitter the SNR experienced by that block, which the encoder makes use of in structuring subsequent blocks. The resulting architecture, which involves layered repetition encoding and successive cancellation decoding, is capacity-achieving, enabling the message to be recovered with the minimum possible number of blocks for the realized channel.
Synthesis and Peptide‐Induced Degradation of Biocompatible Fibers Based on Highly Branched Poly(2‐hydroxyethyl methacrylate) (2006)

Biocompatible fibers (see figure) are prepared by electrospinning branched poly(2-hydroxyethyl methacrylate) copolymers from methanol. These copolymers contain disulfide branch sites that can be cleaved using tripeptides such as glutathione. Cleavage reduces the copolymer molecular weight substantially, leading to complete fiber dissolution.
Highly Efficient Light-Harvesting Ruthenium Sensitizer for Thin-Film Dye-Sensitized Solar Cells (2009)

A high molar extinction coefficient heteroleptic ruthenium complex, incorporating an electron-rich hexylthio-terminal chain, has been synthesized and demonstrated as an efficient sensitizer for dye-sensitized solar cells. With this new sensitizer excellent power conversion efficiency is 11.5% and 4.7% obtained under an irradiation of full sunlight (air mass 1.5 global) in combination with a volatility electrolyte and solid state hole transporting material, respectively. The devices with low volatility electrolyte showed good stability under visible-light soaking at 60 degrees C during 1000 h of accelerated tests.
Genome-Wide lncRNA Microarray Profiling Identifies Novel Circulating lncRNAs for Detection of Gastric Cancer (2016)

Long non-coding RNAs (lncRNAs) can serve as blood-based biomarkers for cancer detection. To identify novel lncRNA biomarkers for gastric cancer (GC), we conducted, for the first time, genome-wide lncRNA screening analysis in two sets of samples: five paired preoperative and postoperative day 14 plasma samples from GC patients, and tissue samples from tumor and adjacent normal tissues. Candidate tumor-related lncRNAs were then quantitated and evaluated in three independent phases comprising 321 participants. The expression levels of lncRNAs were also measured in GC cell lines and the corresponding culture medium. Biomarker panels, lncRNA-based Index I and carcinoembryonic antigen (CEA)-based Index II, were constructed using logistic regression, and their diagnostic performance compared. Fagan's nomogram was plotted to facilitate clinical application. As a result, we identified five novel plasma lncRNAs (<i>TINCR</i>, <i>CCAT2</i>, <i>AOC4P</i>, <i>BANCR</i> and <i>LINC00857</i>), which, when combined in the lncRNA-based Index I, outperformed the CEA-based Index II (<i>P</i> < 0.001) and could distinguish GC patients from healthy controls with an area under the receiver-operating curve (AUC) of 0.91 (95% confidence interval (CI): 0.88-0.95). The lncRNA-based index decreased significantly by postoperative day 14 (<i>P</i> = 0.016), indicating its ability to monitor tumor dynamics. High values of the lncRNA-based index were correlated with tumor size (<i>P</i> = 0.036), depth of invasion (<i>P</i> = 0.025), lymphatic metastasis (<i>P</i> = 0.012) and more advanced tumor stages (<i>P</i> = 0.003). The lncRNA-based index was also able to discriminate GC patients from precancerous individuals and patients with gastrointestinal stromal tumor with AUC values of 0.82 (95% CI: 0.71-0.92) and 0.80 (95% CI: 0.68-0.91), respectively. Taken together, our findings demonstrate that this panel of five plasma lncRNAs could serve as a set of novel diagnostic biomarkers for GC detection.
A joint frequency offset estimation algorithm based on training symbol and virtual subcarriers for CO-OFDM systems (2015)

In this paper, we propose a joint method of frequency offset estimation based on training symbol and virtual subcarriers for coherent optical orthogonal frequency division multiplexing(CO-OFDM) system. In the proposed method, the integer frequency offset is estimated through subtraction between the mode got form the first data subcarriers' position in OFDM symbols and the number of virtual subcarriers inserted in each side of the OFDM symbol, in which the first subcarrier's position can be found at the maximum slope of the fitting curve to virtual subcarriers; While the fractional frequency offset is estimated by periodic characteristic of the training symbol. Theoretical analysis and simulation results show that the estimation accuracy is improved by the proposed method in the additive white Gaussian noise(AWGN) and the dispersive channel. Simultaneously, estimation range of the proposed algorithm is about [-5GHz, +5GHz], satisfying the practical application requirement, and when the optical signal-to-noise ratio(OSNR) is low, it can still operate properly.
A wide-band square-waveguide array polarizer (1973)

A stepped-septum polarizer has been designed that is capable of at least 26 dB of isolation over a 20 percent frequency band. The three-port device may be used to excite high purity left or right circular, as well as tilted linear polarizations in a phased array of square waveguides.
A 1.1 V 2y-nm 4.35 Gb/s/pin 8 Gb LPDDR4 Mobile Device With Bandwidth Improvement Techniques (2015)

The demands on higher bandwidth with reduced power consumption in mobile market are driving mobile DRAM with advanced design techniques. Proposed LPDDR4 in this paper achieves over 39% improvement in power efficiency and over 4.3 Gbps data rate with 1.1 V supply voltage. These are challenging targets compared with those of LPDDR3. This work describes design schemes employed in LPDDR4 to satisfy these requirements, such as multi-channel-per-die architecture, multiple training modes, low-swing interface, DQS and clock frequency dividing, and internal reference for data and command-address signals. This chip was fabricated in a 3-metal 2y-nm DRAM CMOS process.
Ring contraction of 7-chloro-3-phenyl -2H-1,2,4-benzothiadiazine (1979)

7-Chloro-3-phenyl-2H-1,2,4-benzothiadiazine (2) undergoes ring contraction to 6-chloro-2-phenylbenzothiazole (3) when it is heated in inert solvents above 180°. The reaction is markedly promoted by tervalent phosphorus compounds and in the presence of triphenylphosphine or triethyl phosphite, the ring contraction occurs even at room temperature. Photochemical ring contraction has also been observed. The benzothiadiazine (2) can act as a chlorinating agent at high temperatures: this remarkable property is ascribed to its reaction through the tautomeric structure (5a).