gebhart/patrepeval huggingface dataset:
A DNA−Silver Nanocluster Probe That Fluoresces upon Hybridization (2010)

DNA-templated silver nanoclusters (DNA/Ag NCs) are an emerging set of fluorophores that are smaller than semiconductor quantum dots and can have better photostability and brightness than commonly used organic dyes. Here we find the red fluorescence of DNA/Ag NCs can be enhanced 500-fold when placed in proximity to guanine-rich DNA sequences. On the basis of this new phenomenon, we have designed a DNA detection probe (NanoCluster Beacon, NCB) that "lights up" upon target binding. Since NCBs do not rely on Forster energy transfer for quenching, they can easily reach high (>100) signal-to-background ratios (S/B ratios) upon target binding. Here, in a separation-free assay, we demonstrate NCB detection of an influenza target with a S/B ratio of 175, a factor of 5 better than a conventional molecular beacon probe. Since the observed fluorescence enhancement is caused by intrinsic nucleobases, our detection technique is simple, inexpensive, and compatible with commercial DNA synthesizers.
Frontolimbic neural circuitry at 6 months predicts individual differences in joint attention at 9 months (2012)

Elucidating the neural basis of joint attention in infancy promises to yield important insights into the development of language and social cognition, and directly informs developmental models of autism. We describe a new method for evaluating responding to joint attention performance in infancy that highlights the 9- to 10-month period as a time interval of maximal individual differences. We then demonstrate that fractional anisotropy in the right uncinate fasciculus, a white matter fiber bundle connecting the amygdala to the ventral-medial prefrontal cortex and anterior temporal pole, measured in 6-month-olds predicts individual differences in responding to joint attention at 9 months of age. The white matter microstructure of the right uncinate was not related to receptive language ability at 9 months. These findings suggest that the development of core nonverbal social communication skills in infancy is largely supported by preceding developments within right lateralized frontotemporal brain systems.
SnakeSIM: A ROS-based rapid-prototyping framework for perception-driven obstacle-aided locomotion of snake robots (2017)

Biological snakes are capable of exploiting roughness in the terrain for locomotion. This feature allows them to adapt to different types of environments. Snake robots that can mimic this behaviour could be fitted with sensors and used for transporting tools to hazardous or confined areas that other robots and humans are unable to access. Snake robot locomotion in a cluttered environment where the snake robot utilises a sensory-perceptual system to perceive the surrounding operational environment for means of propulsion can be defined as perception-driven obstacle-aided locomotion (POAL). The initial testing of new control methods for POAL in a physical environment using a real snake robot imposes challenging requirements on both the robot and the test environment in terms of robustness and predictability. This paper introduces SnakeSIM, a virtual rapid-prototyping framework that allows researchers for the design and simulation of POAL more safely, rapidly and efficiently. SnakeSIM is based on the Robot Operating System (ROS) and it allows for simulating the snake robot model in a virtual environment cluttered with obstacles. The simulated robot can be equipped with different sensors. Tactile perception can be achieved by using contact sensors to retrieve forces, torques, contact positions and contact normals. A depth camera can be attached to the snake robot head for visual perception purposes. Furthermore, SnakeSIM allows for exploiting the large variety of robotics sensors that are supported by ROS. The framework can be transparently integrated with a real robot. To demonstrate the potential of SnakeSIM, a possible control approach for POAL is considered as a case study.
Petroleum Processing Efficiency Improvement (2012)

A series of volatile crude oils was characterized using the Asphaltene Determinator oncolumn precipitation and re-dissolution method developed at Western Research Institute (WRI). Gravimetric asphaltenes and polars fractions from silica gel chromatography separation of the oils were characterized also. A study to define the differences in composition of asphaltenes in refinery desalter rag layer emulsions and the corresponding feed and desalter oils was conducted. Results indicate that the most polar and pericondensed aromatic material in the asphaltenes is enriched in the emulsions. The wax types and carbon number distributions in the two heptaneeluting fractions from the Waxphaltene Determinator separation were characterized by repetitive collection of the fractions followed by high temperature gas chromatography (GC) and Fourier transform infrared spectroscopy (FTIR). High resolution Fourier transform ion cyclotron resonance mass spectrometry (FT-ICRMS) was conducted by researchers at the Florida State University National High Magnetic Field laboratory in a no-cost collaboration with the study.
An empirical comparison of visualization tools to assist information retrieval on the web (2001)

Abstract Visualizations of subspaces on the World Wide Web can provide users the ability to identify relevant information from a set of Web pages, while gaining new insights or understanding of the space. This study tested three classes of visualization techniques, distortion, zoom, and expanding outline, to better understand which classes of visualization techniques may better represent the underlying structure. The effects of different visualization techniques on user performance on information searching tasks and the effects of different sizes of the Web spaces were studied. Eighty participants were asked to search information with and without a visualization tool over the large Web space. The factors that may have caused cognitive overloads are further discussed.
Voltammetric Studies of Porous Molybdenum Electrodes for the Alkali Metal Thermoelectric Converter (1986)

Voltammetry of partially oxidized porous molybdenum alkali metal thermoelectric converter (AMTEC) electrodes from ∼600 to ∼1000 K revealed a series of redox processes within the operational voltage range of the AMTEC device. The most important of these processes involve reactions that add sodium to , , and . The redox processes can be used as an in situ analytical probe of oxide species in porous molybdenum electrodes. These constituents are important in establishing the electronic and ionic conductivities of AMTEC electrodes. The estimated equilibrium potentials of these reactions provide improved estimates of the free energies of formation of , , and. In the AMTEC operating regime, there is evidence for the comparatively slow corrosive attack by on molybdenum. The ionic conductivity of measured from 600 to over 1000 K shows sharp increases in conductivity at ∼750, 865, and 960 K. The conductivity is sufficiently large at to explain the observed electrochemical phenomena, as well as enhanced sodium transport in AMTEC electrodes below the freezing point (960 K) of . The results of this study are relevant to AMTEC device performance and also provide more detailed information about the ternary Na‐Mo‐O phase diagram in the range of conditions relevant to the AMTEC device.
Synthesis and Structure−Activity Relationships of Retinoid X Receptor Selective Diaryl Sulfide Analogs of Retinoic Acid (1996)

Retinoids exert their biological effects by binding to and activating nuclear receptors that interact with responsive elements on DNA to promote gene transcription. There are two families of retinoid receptors, the retinoic acid receptor (RAR) family and the retinoid X receptor (RXR) family, which are each further divided into three subclasses: RAR alpha, beta, gamma and RXR alpha, beta, gamma. Herein we describe the synthesis and structure-activity relationships of a new series of diaryl sulfide retinoid analogs that specifically bind and transactivate the RXRs. Furthermore, the sulfoxide and sulfone derivatives of these analogs are partial agonists which activate the RXRs only at high concentrations. Thus, these compounds possess a potential site of metabolic deactivation and may have less prolonged systemic effects than other compounds with arotinoid-like structures. We show also that these compounds have activity in nontransfected cells as demonstrated by their ability to induce TGase activity in HL-60 cells. Finally, we corroborate our earlier report that RXR-specific agonists may possess reduced teratogenic toxicity compared to RAR-specific agonists since these compounds are much less potent inhibitors of chondrogenesis than RAR-specific agonists such as TTNPB.
Effect of pH and salt concentration on bimodal inclusion of a nitroxide by cyclodextrins (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEffect of pH and salt concentration on bimodal inclusion of a nitroxide by cyclodextrinsYashige Kotake and Edward G. JanzenCite this: J. Am. Chem. Soc. 1989, 111, 19, 7319–7323Publication Date (Print):September 1, 1989Publication History Published online1 May 2002Published inissue 1 September 1989https://pubs.acs.org/doi/10.1021/ja00201a006https://doi.org/10.1021/ja00201a006research-articleACS PublicationsRequest reuse permissionsArticle Views236Altmetric-Citations41LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Purification, biochemical characterization, and genetic cloning of the phytase produced by <i>Burkholderia</i> sp. strain a13 (2015)

A phytase-producing bacterium, Burkholderia sp. a13 (JCM 30421), was isolated from Lake Kasumigaura by enrichment cultivation using minimum medium containing phytic acid as the sole phosphorus source. The phytase production by strain a13 was induced by the presence of phytic acid and repressed by the addition of glucose. The purified enzyme had a molecular weight of 44 kDa and a phytase activity of 174 μmol min(-1) mg(-1). The enzyme showed broad substrate specificity, but the highest activity was observed with phytic acid. The enzyme activity was strongly inhibited by Cu(2+), Zn(2+), Hg(2+), and iodoacetic acid, indicating the requirement of a thiol group for the activity. Genetic cloning reveals that the mature portion of this enzyme consists of 428 amino acids with a calculated molecular weight of 46 kDa. The amino acid sequence showed the highest similarity to the phytase produced by Hafnia alvei with 48% identity; it also contained histidine acid phosphatase (HAP) motifs (RHGXRXP and HD), indicating the classification of this enzyme in the HAP phytase family. We have successfully expressed the cloned gene in Escherichia coli from its putative initiation codon, showing that the gene actually encodes the phytase.
Muscle recovery after immobilisation by external fixation (1999)

We immobilised the right hindlimbs of six-month-old female Wistar rats for four weeks using a biplanar external fixation bridging the knee. The untreated left limbs served as a control group. An additional group of rats was allowed to recover for four weeks after removal of the frame. Immobilisation caused reduction in the wet weights of approximately 50% in the gastrocnemius, quadriceps, soleus and plantaris muscles; this was not restored completely after remobilisation. There was an increase in the activity of acid phosphatase of approximately 85% in the gastrocnemius and quadriceps muscles whereas that of creatine phosphokinase was reduced by about 40%. These values returned to nearly normal after remobilisation. Histological and ultrastructural examination showed a marked myopathy of the gastrocnemius muscle after immobilisation although the morphology was largely restored after remobilisation. We conclude that after four weeks of remobilisation, hind-limb muscles do not return to preimmobilisation weights, although biochemical activities and ultrastructural appearance are largely restored.
Implementation of Helical Wave Propagation Motion for a Snake Robot to Across a Branch on a Pipe (2018)

In this study, we propose a type of motion for snake robots that involves wrapping around the outside of a pipe to overcome a branch point on it. This new motion uses a hyperbolic function to make a helical wave curve, which is then propagated by shifting the shape of the hyperbolic function along the body of snake robot. The joint angles of the snake robot are derived by calculating the curvature and torsion of the curve on the basis of the formula of the continuous curve model. In this paper, we describe setting guidelines for each parameter. Some experimental results are shown to validate the effectiveness of the new motion.
Bioassays of Polycyclic Aromatic Hydrocarbons using CYP1A1-luciferase Reporter Gene Expression System in Human Breast Cancer MCF-7 Cells (2003)

Biological activities of PAHs are not known although PAHs are considered as carcinogens. Recent industrial society has human widely exposed to PAHs (polynuclear aromatic hydrocarbons) that are comming from the incomplete combustion of organic material as wider spread environmental contaminants. Our laboratory have been studied the effect of PAHs in the human breast cancer MCF-7 cells. In this study, we examined the human breast cancer MCF-7 cell as a new system to evaluate bioactivity of PAHs. We have selected 13 PARs to examine bioassay using CYP1A1-luciferase reporter gene expression system where CYP1A1 l.6 Kb Sflanking region DNA was cloned in front of luciferase reporter gene and this plasmid was transfected into MCF-7 cells transiently. This cells then used for the study to observe the effect of PAHs. We demonstrated that PARs induced the CYP1A1 promoter, CYPIAI mRNA and 7-ethoxyresolufin O-deethylao;e (EROD) activities in a concentration-dependant manner. None of PAHs that we have tested showed stronger stimulatory effect on CYP1 gene expression than TCDD. Benz(a)anthracene and benzo(b)tluoranthene were weak responders to CYP1A1 promoter activity stimulation, CYP1A1 mRNA and EROD induction in MCF-7 cells and these chemicals seemed to respond less either CYP1A1 mRNA or EROD than CYP1A1 promoter activity. Benzo(k)fluoranthene, chrysene, and dibenzo(a,h)anthracene showed strong response to CYP1A1 promoter activity stimulation, CYP1A1 mRNA increase and also EROD induction in MCF-7 cells. Results of dose response study suggested that two strong responding PAHs, such as benzo(k)fluoranthene and dibenzo(a,h )anthracene might be mediated through Aryl hydrocarbon receptors system in MCF-7 cells.
Speaking Up Is Related to Better Team Performance in Simulated Anesthesia Inductions (2012)

This study provides empirical evidence and shows mechanisms for the positive relationship between speaking-up behavior and technical team performance.
[Effect of food deprivation on acid-base and blood-gas parameters]. (1982)

The changes of the acid-base- and blood-gas parameters were continuously measured during a two-day food abstinence (but fluid intake free of calories) by means of the blood-gas-automaton ABL 1 with the help of 20 test persons. The denutrition causes a decrease of the metabolic components and of the pCO2, but not of the blood-pH and pO2. The decrease of the concentrations of BE (about 2 mmol/l) as well as HCO3 and TCO2 (in each case 2-3 mmol/l) caused by abstain from food are no indication for a therapy.
Acute Effects of Aerosolized Iloprost in COPD Related Pulmonary Hypertension - A Randomized Controlled Crossover Trial (2012)

Controlled-Trials.com ISRCTN61661881.
Iron Sulfides Formed from Aqueous Solution at Low Temperatures and Atmospheric Pressure (1964)

Several different iron sulfides have been synthesized from aqueous sulfide solutions at low temperatures (20°-90° C.) and atmospheric pressure and identified by means of X-ray diffraction and/or chemical analysis. These are tetragonal FeS, pyrite, marcasite, a magnetic cubic iron sulfide of the spinel structure type, pyrrhotite, and an X-ray amorphous precipitated iron sulfide of composition approximating FeS. The nature of the resulting iron sulfide depends upon many factors, the most important of which are pH, temperature, the presence of specific oxidizing agents, and the type of iron source material used as a reactant. Tetragonal FeS was formed over a wide range of conditions and was the iron sulfide most commonly encountered in this study. It results from the reaction of hydrogen sulfide with fine-grained goethite under conditions simulating those in natural marine sediments. The substance described as hydrotroilite in many sedimentary occurrences is believed to be, at least in part, poorly crystallized tetragonal FeS. Tetragonal FeS has been found in the sediments of the Mystic River, Boston, Massachusetts, and in an iron sulfide concretion from the sediments of the Black Sea. The initial corrosion product of metallic iron in $$H_{2}S$$, which has been called kansite, is tetragonal FeS. The material originally denoted as melnikovite by Doss (1912) is believed to have been a mixture of phases containing one or more of several known magnetic iron sulfides. The substance called melnikovite by Volkov (1961) from the Black Sea concretion is shown to be the magnetic cubic iron sulfide synthesized in the present study.
Fast discovery and visualization of conserved regions in DNA sequences using quasi-alignment (2013)

Quasi-alignment-based algorithms can detect highly similar regions and conserved areas across multiple sequences. Since the run time is linear and the sequences are converted into a compact clustering model, we are able to identify conserved regions fast or even interactively using a standard PC. Our method has many potential applications such as finding characteristic signature sequences for families of organisms and studying conserved and variable regions in, for example, 16S rRNA.
Direct Imaging of Sketched Conductive Nanostructures at the LaAlO3/SrTiO3 Interface (2017)

Nanoscale control of the quasi-two-dimensional electron gas at the LaAlO3/SrTiO3 (LAO/STO) interface by a conductive probe tip has triggered the development of a number of electronic devices. While the spatial distribution of the conductance is crucial for such devices, it is challenging to directly visualize the local electrical properties at the buried interface. Here we demonstrate conductivity imaging of sketched nanostructures at the LAO/STO interface by microwave impedance microscopy (MIM) with a lateral resolution on the order of 100 nm. The sheet conductance extracted from the MIM data agrees with the transport measurement. The tip-induced insulator-to-metal transition is observed above a threshold voltage of +4 V. Our work paves the way to study emergent phenomena at oxide interfaces by probing nanoscale conductance distribution.
Gérard Chastagnaret, Humos y sangre. Protestas en la cuenca de las piritas y masacre en Riotinto (1877-1890). Trad. de María Ángeles Casado Sánchez, Alicante Publicacions de la Universitat d’Alacant, 2017, 456 páginas (2019)

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Multiscale Optical Systems (2009)

Get PDF Email Share Share with Facebook Share on X Post on reddit Share with LinkedIn Add to Mendeley Add to BibSonomy Share with WeChat Get Citation Copy Citation Text D. J. Brady, "Multiscale Optical Systems," in Frontiers in Optics 2009/Laser Science XXV/Fall 2009 OSA Optics & Photonics Technical Digest, OSA Technical Digest (CD) (Optica Publishing Group, 2009), paper CWB2. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
임진왜란 이후 조선 권법의 변화에 관한 연구 (2003)

The purpose of this study was to compare with the differences Kwonbeob (weapon-free martial arts) movements in Muvedobotongji and chines tactic books such as Kihyosinseo, Mubiji which were source books of Muyedobotongji, what is more, Muyejebobeunyeuksokjib that was printed after Imjin War(1592) during that time Korean were adapted the chines martial arts. However we can riot find the actions or experts, so we have no choice but using books mentioned above. Therefore we rely only on contents in the hooks and detail Se which describe the postures or basic skills of martial arts, and compare its differences. The result of this comparison of 22 Se in Kwonbeob of Muyedobotongji is the following ; firstly, 4 cases are similar each other in the forms and actual techniques, secondly, 5 cases are different in the actual techniques, but the forms are similar, thirdly, 10 cases are different in the forms, but actual techniques are similar, and lastly, 3 cases are different in the actual techniques and forms. In conclusion, Kwonbeob of Muyedobotongji has been affected by Chinese Kwonbeob, it has been separately developed when comparing to the Chinese Kwonbeob.
A genetic algorithm for constrained via minimization (2003)

Constrained via minimization is a typical optimization problem in very large scale integrated circuit (VLSI) routing. It is used to minimize the number of vias introduced in a VLSI routing. The first genetic algorithm for the constrained via minimization problem is proposed. Experimental results show that the developed genetic algorithm can consistently produce the same or better results than the best deterministic constrained via minimization algorithms.
Solid-State Polyimide Foaming from Powder Precursors: Effect of Morphology and Process Parameters on the Diffusive Phenomena (2004)

Solid poly(amic acid) (PAA) precursor is used for foaming into microspheres or foams depending on whether the powder particles are free or confined inside a mold. Solid-state foaming of powder precursors is studied by examining concurrent and competitive phenomena that determine the morphology and physical properties of the foam unit cell. Simultaneous analysis through thermo gravimetric analysis (TGA) and modulated differential scanning calorimetry (MDSC) is proposed for the characterization of important transitions during the blowing process. Effects of particle size and shape on bubble growth will be addressed.