gebhart/patrepeval huggingface dataset:
Immune unresponsiveness of spleen cells from lipopolysaccharide‐treated mice to particulate thymus‐dependent antigen I. Evidence for differentiation signal defect (1981)

The cellular basis of the immune unresponsiveness induced by lipopolysaccharide (LPS) was analyzed at the B and T cell level. The immunosuppressive effect of LPS is not related to altered B cell competence. Inhibition of antibody responses was observed only for thymus-dependent (TD) and not for thymus-independent antigens. In the presence of T cell-replacing factor (TRF), LPS-sensitized B lymphocytes respond to TD antigenic stimulation and differentiate into antibody-forming cells. Evidence is presented for a decreased helper activity of LPS-sensitized T lymphocytes and for a defective production of TRF in concanavalin A-stimulated spleen cells from LPS-treated mice. The implication of a cell compartment other than T is discussed.
Application ofGAS Chromatographic Methodsfor Air Pollution Studies (1961)

(1961). Application of GAS Chromatographic Methods for Air Pollution Studies. Journal of the Air Pollution Control Association: Vol. 11, No. 1, pp. 34-44.
Uncomplicated HL-A Matched Sibling Bone Marrow Graft for Combined Immune Deficiency (1972)

When an apparently identical HL-A donor can be found and satisfactorily checked by the mixed lymphocyte reaction, it is worth attempting simple bone marrow grafting in a patient with combined immune deficiency syndrome who otherwise would die. Immunocompetence was given in this way to a baby girl by her 4-year-old brother and was confirmed by the presence of Y-chromosome in most of the transforming lymphocytes. IgA was late to emerge, presumably owing to the immaturity for IgA of the donor's bone marrow.
Supplementary Table 1 from Relationship between Quantitative <i>GRB7</i> RNA Expression and Recurrence after Adjuvant Anthracycline Chemotherapy in Triple-Negative Breast Cancer (2023)

&lt;p&gt;XLS file - 31K, Patient characteristics by GRB7 expression.&lt;/p&gt;
<title>Extending HIPPI at 800-mega-bits-per-second over serial links using HOT ROD technology</title> (1991)

This paper describes a serial link solution at 1. 25 Giga baud to extend the current distance of 25meters to up to 2 kilometers for the American National Standards Institute (ANSI)''s High Performance Parallel Interface (HIPPI) standard. The proposal uses Gazelle''s HOT ROD technology along with fiber optic links to serialize the HIPPI interface for data rates of 800 Megabits per second (Mbps). This scheme enables the use ofremote peripheral access interconnection of Local Area Network (LAN)s and Small Area Network (SAN) applications.
Bibliography (2005)

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Trunnion Failure in Revision Total Knee Arthroplasty (2021)

In revision total knee arthroplasty, joint kinematics must be maintained amid bone and ligamentous insufficiency. Current modular designs address defects while allowing for intraoperative prosthesis customization through a variety of stem extensions and constraints. Additional constraint improves knee stability while increasing stress at the implant-host interface and modular junction of the implant. This renders the prosthetic stem-condyle junction more prone to fatigue failure. We report 2 cases of prosthetic stem-condyle junction failure in in a varus-valgus constrained revision total knee arthroplasty.
Trans-cultural aspects of social anxiety disorder and related conditions: a Brazilian case series and a review of international clinical studies (2006)

Cross-cultural studies have much to teach clinicians and researchers alike about psychopathology in general and about social anxiety disorder (SAD) in particular. Unfortunately, little is known about the degree and the mechanisms through which cultural environment may influence clinical manifestations of SAD. OBJECTIVE: Our objective was to identify culture-related clinical patterns in SAD and related disorders. METHODS: We described socio-demographic and clinical characteristics of a sample of 62 adult outpatients with SAD seen at a university clinic for anxiety and depressive disorders in Rio de Janeiro, Brazil, and compared them with those reported in clinical samples from North America, Europe, Asia and Oceania identified through a systematic review in Medline, PsychINFO, and LILACS. RESULTS: Our comparison of trans-cultural features of SAD lends partial support to Heimberg's (1997) contention that the majority of socio-demographic features and symptoms of this disorder are relatively independent of geographic and cultural differences. CONCLUSION: Patients with SAD were almost universally characterized by: 1) a predominance of males in clinical samples; 2) early onset of the disorder; 3) high educational attainment; and 4) great frequency of comorbidities.
Autoxidation of nonane and decane: a product study (1994)

The autoxidation of nonane and decane has been shown to occur in three stages. The initial stage leads t o alkyl hydroperoxide formation and in the second stage the hydroperoxide decomposes to produce alcohols and ketones as major products. These studies support the proposal that hydroperoxide decomposition in the second stage occurs by a radical-induced decomposition. In the third stage the products are oxidised in competition with the alkane. Under the conditions of the autoxidation, the alkanes produce γ-lactones as the major ester components and carboxylic acids are formed in the latter stages of the autoxidation. Decan-2-one is shown to be the precursor of heptan-1-01 and octanal.
Image-guided endoscopy for lung-cancer assessment (2002)

A system for virtual-endoscopic 3D medical image assessment and follow-on live endoscopy is described. The development and results focus on 3D CT images of the chest and lung-cancer assessment. Two stages are involved in the assessment. In Stage-1, the physician uses a series of tools for visualization and 3D central-axes analysis to build a guidance plan (a "case study"). Next, during Stage-2 endoscopy, the physician links the computer system and case study to the endoscope. The endoscopic video is registered to 3D virtual image data to give the physician "augmented reality" information to better perform the endoscopy. Results illustrate the system's utility for animal and human cases.
Suppression of acute pancreatitis by L-lysine in mice (2015)

L-lysine treatment attenuates pancreatic tissue injury induced by L-arginine by inhibiting the release of the inflammatory cytokine IL-6 and enhance antioxidant activity. These effects may involve upregulation of anti-inflammatory factors and subsequent downregulation of IL6.
On a standard approach for substrate noise modelling in mixed signal IC's (2005)

An alternative way of using the ICEM model is described. This model is considering each part of a mixed signal design: the PCB, the package, the bonding wires, the padring and the core of the digital chip. By adding some elements to this model, we can simulate the transient substrate voltage induced by the digital part of a mixed signals integrated circuit. A test-chip was implemented in a 0.35 /spl mu/m BiCMOS process to validate this extended ICEM model. Some spice simulations of the modelled test-chip, running in many different configurations, are exposed. The results of those simulations are compared to measurements and reveal the advantages and drawbacks points of the methodology. We also describe what has to be done to apply this method to a realistic digital circuit.
Prolactin is transported across the epithelium of the jejunum and ileum of the suckling rat (1989)

Milk prolactin is transferred from the gastrointestinal tract to the circulation of the suckling rat. To identify the site of prolactin penetration and to determine the mechanism by which the hormone traverses the mucosal barrier, we followed the uptake of prolactin from ligated loops of jejunum or ileum in vivo by three methods: autoradiography, transport of prolactin-gold conjugates, and immunocytochemistry. Autoradiographic studies demonstrated specific binding sites for 125I-prolactin on apical membranes of the jejunum and ileum. Excess cold prolactin reduced radiolabel in apical and basal compartments. Gel autoradiography of portal sera showed the presence of intact prolactin and a prolactin fragment following jejunal transport but only a prolactin fragment following ileal transport. Uptake of prolactin-gold conjugates demonstrated that, in the jejunum, label was present at the luminal surface, within endosomal compartments and lysosomes, in basal coated and smooth vesicles, within basal coated pits, and beyond the basolateral surface. In the ileum, label was found at the luminal surface; within the tubulocisternae, endosomal vesicles, lysosomes, and basal smooth vesicles; and beyond the basolateral surface. Immunoreactive prolactin was present throughout the transepithelial pathways. This study demonstrates that prolactin is selectively and nonselectively absorbed in the jejunum and ileum and that the hormone is directed either to the lysosome for degradation or across the epithelium by means of a transcellular pathway.
Giant magnetoresistive sensors for rotational speed control (1999)

This article demonstrates spin valve (sv) sensor applications as rotational speed control devices, in a Wheatstone bridge configuration. The sensor architecture uses two active self-biased sv elements (dimensions 400×6 μm2) in a CoZrNb flux guide. The other two spin valves are inactivated for external fields inferior to 150 Oe. Inactivation is achieved by increasing the ferromagnetic coupling of the inactive spin valves above 200 Oe, by roughening the surface of the underlying oxide layer (12 Å average roughness). When excited by a magnetized wheel with 60 N-S poles rotating at 360 rpm, the sensor yields a 400 mV pp square wave output with rise/fall times corresponding to an angular resolution of 0.17°. Amplitude is independent of speed (0–3000 rpm), and of sensor to wheel separation (0.5⩽d(mm)⩽2.0). Bridge output decreases 26% when temperature is increased to 150 °C. Bridge offset of 350 mV is caused by the resistance differences between the active and inactive sv elements.
Synthesis of 6‐Aryl‐1,6‐dihydrodipyrazolo[3,4‐b:4,3‐c]pyridines (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
Wearable technology for spine movement assessment: A systematic review (2017)

Continuous monitoring of spine movement function could enhance our understanding of low back pain development. Wearable technologies have gained popularity as promising alternative to laboratory systems in allowing ambulatory movement analysis. This paper aims to review the state of art of current use of wearable technology to assess spine kinematics and kinetics. Four electronic databases and reference lists of relevant articles were searched to find studies employing wearable technologies to assess the spine in adults performing dynamic movements. Two reviewers independently identified relevant papers. Customised data extraction and quality appraisal form were developed to extrapolate key details and identify risk of biases of each study. Twenty-two articles were retrieved that met the inclusion criteria: 12 were deemed of medium quality (score 33.4-66.7%), and 10 of high quality (score >66.8%). The majority of articles (19/22) reported validation type studies. Only 6 reported data collection in real-life environments. Multiple sensors type were used: electrogoniometers (3/22), strain gauges based sensors (3/22), textile piezoresistive sensor (1/22) and accelerometers often used with gyroscopes and magnetometers (15/22). Two sensors units were mainly used and placing was commonly reported on the spine lumbar and sacral regions. The sensors were often wired to data transmitter/logger resulting in cumbersome systems. Outcomes were mostly reported relative to the lumbar segment and in the sagittal plane, including angles, range of motion, angular velocity, joint moments and forces. This review demonstrates the applicability of wearable technology to assess the spine, although this technique is still at an early stage of development.
Facial emotion classification using active appearance model and support vector machine classifier (2009)

Automatic analysis of human face expression is an interesting and non-trivial problem. In the last decade, many approaches have been described for emotion recognition based on analysis of facial expression. However, little has been done in the sub-area of the recognition of facial emotion intensity levels. This paper proposes the analysis of the use of Active Appearance Models (AAMs) and Support Vector Machine (SVM) classifiers in the recognition of human facial emotion and emotion intensity levels. AAMs are known as a tool for statistical modeling of object shape/appearance or for precise object feature detection. In our case, we examine their properties as a technique for feature extraction. We analyze the influence of various facial feature data types (shape/texture/combined AAM parameter vectors) and the size of facial images on the final classification accuracy. Then, approaches to proper C-SVM classifiers (RBF kernel) training parameter adjustment are described. Moreover, an alternative way of classification accuracy evaluation using the human visual system as a reference point is discussed. Unlike the usual to the approach evaluation of recognition algorithms (based on comparison of final classification accuracies), the proposed evaluation schema is independent of the testing set parameters, such as number, age and gender of subjects or the intensity of their emotions. Finally, we show that our automatic system gives emotion categories for images more consistent labels than human subjects, while humans are more consistent in identifying emotion intensity level compared to our system.
Angular distributions of Auger electrons from surfaces: Conclusions from full multiple-scattering simulations (1994)

We address some of the recent controversies regarding the interpretation of Auger electron diffraction patterns by simulating those from the 64 eV M2,3VV and the 914 eV L3VV lines from a Cu(001) surface. The lower-energy diffraction pattern, in particular, is found to be strongly dependent on the angular momentum l of the emitted Auger electrons, in line with the observations of some other authors. However, we find that both peaks and dips are observed on the same diffraction pattern at the projections of different atomic rows, indicating that the angular momentum of the source wave cannot be the only determinant of these features. We find that the distance of the scatterer from the source, as well as overlap and interference effects from scatterers in other atomic rows to be an equally important determining factor. On comparing our simulations with experimental diffraction patterns, we find that, for an l=3 source wave, our simulations agree remarkably well with the data from both Auger lines.
Radiation Pressure Assisted Acousto-Optical Transducer (2018)

We study the acousto-optical response of the optomechanical resonators in subthreshold regime and demonstrate that the reduced damping due to radiation pressure can be used for high sensitivity detection of acoustic waves.
Highly efficient grating mirror enables high power fundamental mode thin-disk laser emitting in the green by SHG (2015)

There are several benefits of green laser radiation for laser material processing of copper [1]. For example, deep penetration welding of copper [2] is more efficient in the green wavelength region due to an approximately 7-10 times higher absorption of copper than in the commonly used near infrared region. High power green laser radiation leads to more reproducible and stable processes in the electronic industry where scattered light can lead to damages and destruction of the processed components. [3]
Acute effects of ethanol on GABAA and glycine currents in the lateral habenula neurons of young rats (2013)

Compelling evidence has shown a pivotal role of dopaminergic function in drug addiction. Recently, the lateral habenula (LHb) has attracted a great deal of attention as another target for abused drugs in the brain because its role in regulating dopaminergic system, among others. GABA and glycine are major inhibitory neurotransmitters. Their corresponding receptors are key targets of ethanol. The properties of these receptors in LHb neurons and their responses to ethanol in particular however, remain unknown. Using the patch clamp techniques, we examined the effects of ethanol on the chloride currents elicited by GABA and glycine in LHb neurons acutely dissociated from 10-20 day-old Sprague-Dawley rats. We show that GABA concentration-dependently elicited a bicuculline sensitive inward current in 96% (130/140) of the neurons tested. Ethanol (43.2 mM) suppressed current elicited by a wide range of concentrations (1-300 μM) of GABA in 74% (35/47) cells tested. Ethanol suppression is dependent on its concentrations but not on membrane potentials of the neurons. Moreover, glycine concentration-dependently elicited an inward current in 94% (112/120) of the neurons tested. Both strychnine and picrotoxin concentration dependently suppressed glycine current with IC<sub>50</sub> of 220 nM and 813 μM, respectively. Ethanol (43.2 mM) potentiated current elicited by unsaturated but not saturated concentrations of glycine. Thus, the LHb neurons of young rats contain both functional GABA<sub>A</sub> and glycine receptors which are sensitive to ethanol at pharmacologically relevant concentrations. These effects of ethanol might be important in the control of the activity and output of LHb neurons.
Chemical modification of monolithic poly(styrene–divinylbenzene) polyHIPE® materials (1996)

Monolithic samples of highly porous poly(styrene/DVB) PolyHIPE® have undergone a number of electrophilic aromatic substitution reactions, namely sulfonation, nitration and bromination. Mild, hydrophobic reagents and homogeneous reaction conditions were sought in an effort to achieve uniform chemical modification, to a reasonable degree of substitution, throughout the large polymeric structures. Thus, sulfonation was carried out with lauroyl sulfate in cyclohexane, nitration with tetrabutylammonium nitrate-trifluoroacetic anhydride (TBAN–TFAA) in dichloromethane and bromination with bromine–stannic chloride in dichloromethane. An average degree of sulfonation of 2.4 mmol g–1 was achieved, with a drop in sulfonic acid content of approximately 1 mmol g–1 from surface to centre. Nitration occurred to a lesser extent, with similar differences in substitution between surface and centre being observed. PolyHIPE® monolithic samples were brominated to an extent of 3.6 mmol g–1 furthermore, this was uniform across the entire substrate. The differences in extent of each reaction are explained by consideration of such factors as the nature of the solvent, polarity of the reagents and compatibility between the reagents and the polymer matrix throughout the reactions.
Cdk9 phosphorylates Pirh2 protein and prevents degradation of p53 protein (2013)

Several reports have pointed to the negative involvement of p53 in transcriptional regulation of the human immunodeficiency virus type 1 long-terminal repeat (HIV-1 LTR). We recently demonstrated that through their physical interaction, cdk9 phosphorylates p53 on Ser-392, leading to p53 stability and accumulation. As a result, p53 stalled transcriptional elongation of the HIV-1 LTR and significantly reduced HIV-1 replication in primary microglia and astrocytes. Therefore, we sought to identify the mechanisms used by cdk9 to allow this p53 function. Using western blot analysis, we found that cdk9 promotes inhibition and phosphorylation of Mdm2 on Ser-395, thus preventing degradation of p53, a protein that is directly involved in promoting p53 ubiquitination. On the other hand, we showed that cdk9 phosphorylates Pirh2 on Ser-211 and Thr-217 residues through their physical interaction. Phosphorylation of Pirh2 renders it inactive and may contribute to p53-inhibition of transcriptional elongation of the HIV-1 LTR. Hence, we suggest that phosphorylation of Pirh2 may be a novel target for the inhibition of HIV-1 gene expression.
Studies on Copper Metabolism (1956)

Abstract 1. The morphology of the erythrocytes has been studied in 22 normal swine, 65 swine deficient in copper, and 16 swine deficient in iron. The mean values (± the standard deviation) for the volumes of packed red cells in the three groups were 42 ± 2.5, 21 ± 6.6, and 21 ± 6.1 ml/100 ml., respectively. The mean values for the mean corpuscular volumes were 55 ± 3.1, 43 ± 7.1, and 36 ± 5.3, respectively. The mean values for the mean corpuscular hemoglobin concentrations were 33 ± 1.1, 29 ± 2.3, and 28 ± 3.0, respectively. 2. The addition of 11 water-soluble B vitamins, 4 fat-soluble vitamins, ascorbic acid, and minerals (with the exception of copper) to the copper-deficient milk diet did not prevent or delay the development of anemia, modify the morphology of the red cells or alter the degree of hypoferremia. 3. The normoblasts in the marrow of a copper-deficient pig were similar morphologically to those in the marrow of a pig deficient in iron. 4. The intravenous administration of one Gm. of iron, given prior to the development of copper-deficiency, did not delay or prevent the development of anemia. 5. It is concluded that the anemia of copper-deficiency in swine is morphologically similar to the anemia due to iron deficiency in swine.
Gorenstein polytopes with trinomial $h^*$-polynomials (2015)

The characterization of lattice polytopes based upon information about their Ehrhart $h^*$-polynomials is a difficult open problem. In this paper, we finish the classification of lattice polytopes whose $h^*$-polynomials satisfy two properties: they are palindromic (so the polytope is Gorenstein) and they consist of precisely three terms. This extends the classification of Gorenstein polytopes of degree two due to Batyrev and Juny. The proof relies on the recent characterization of Batyrev and Hofscheier of empty lattice simplices whose $h^*$-polynomials have precisely two terms. Putting our theorem in perspective, we give a summary of these and other existing results in this area.
New results from long-term observations of Cyg X-1. (1975)

Observations of Cyg X-1 between October 1974 and July 1975 reveal a persistent 5.6 day modulation of the 3-6 keV X-ray intensity, having a minimum in phase with superior conjunction of the HDE 226868 binary system. The modulation is found to be most pronounced just prior to the April-May 1975 increase of Cyg X-1, after which both the modulation and intensity are at their lowest values for the entire duration of the observations. These data imply that the X-ray emission from Cyg X-1 arises from the compact member of HDE 226868, and that the increase of April-May 1975 may have represented the depletion of accreting material which had not yet been mixed into a cylindrically symmetric accretion disk about the compact member.
In vitro comparison of intracranial stent visibility using various concentrations of gadolinium contrast agent under 1.5 T and 3 T MR angiography (2016)

The Enterprise stent demonstrated good luminal visibility regardless of gadolinium concentration. The relative in-stent signals were more predictable in the Enterprise stent with various doses of gadolinium. Therefore, the Enterprise stent has been shown to provide better in-stent visibility compared with the Helistent using various gadolinium doses.