gebhart/patrepeval huggingface dataset:
Ultradispersive prisms and narrow-band tunable filters combining dispersion of atomic resonances and photonic band-gap structures (2000)

It is shown that the combination of resonance-enhanced dispersion of an atomic or molecular gas with the dispersion of a photonic band-gap (PBG) structure gives rise to new features in the dispersion and transmission of a hybrid resonant gas/PBG system, including the appearance of narrow passbands in the hand gap and stop bands outside the band gap, as well as the enhancement of the dispersion of the structure within a narrow spectral range. The possibility of creating narrow-passband and narrow-stopband filters and ultrarefractive prisms combining the dispersion properties of resonant gases and PBG structures is demonstrated. Transmissive and dispersive properties of gas-filled PBG structures can be controlled by varying the gas pressure and by tuning the band gap with respect to the frequency of an atomic or molecular resonance in a gas. Gas-filled two-dimensional PBG structures can be used for numerous high-resolution and high-precision spectroscopic applications, as well as for spectrally resolved Raman imaging of gas flows and plasmas.
PSYCHOLOGIC IMPACT OF CIRCUIT WEIGHT TESTING AND TRAINING IN CARDIAC PATIENTS (1984)

Ewart, C. K.; Stewart, K. J. FACSM; Keleman, M. H.; Gillilan, R. E.; Valenti, S. A.; Manley, J. D.; Keleman, M. D. Author Information
Movement-assisted sensor deployment (2005)

Sensor deployment is an important issue in designing sensor networks. We design and evaluate distributed self-deployment protocols for mobile sensors. After discovering a coverage hole, the proposed protocols calculate the target positions of the sensors where they should move. We use Voronoi diagrams to discover the coverage holes and design three movement-assisted sensor deployment protocols, VEC (vector-based), VOR (Voronoi-based), and minimax based on the principle of moving sensors from densely deployed areas to sparsely deployed areas. Simulation results show that our protocols can provide high coverage within a short deploying time and limited movement.
Low frequency noise in p-InAsSbP/n-InAs infrared photodiodes at 300K and 77K (2018)

International audience
Wasting and lipodystrophy in patients infected with HIV: a practical approach in clinical practice. (2001)

The care of patients who have HIV infection must address multiple medical, psychological, and socioeconomic factors. Because of the time constraints of a typical 15-minute office visit, important issues may be overlooked unless the physician has a clear concept of priorities and a clear method of tracking information. Although the medical aspects--viral control--must take priority, the psychological and social consequences of the illness must not be ignored. Nutritional evaluation and counseling must be addressed because nutritional disturbances often adversely affect the general health of patients who are infected with HIV. Important nutritional complications of HIV infection are the syndromes of wasting and lipodystrophy. However, the onset of wasting may not be heralded by a change in the patient's weight. In patients who have AIDS, the mechanism leading to a loss of skeletal muscle mass has not been identified. HIV-related lipodystrophy consists of accumulation of fat in the subcutaneous tissues of the lower trunk, abdominal viscera, and dorsocervical region with loss of fat from the upper and lower extremities, buttocks, and face. Lipodystrophy in association with HIV infection is not the same as the wasting syndrome of protein-energy malnutrition. An early sign of lipodystrophy is facial wasting. The treatment of the nutritional complications of HIV infection includes exercise; nutritional counseling; and in selected patients, androgenic hormones, anabolic steroid hormones, and human growth hormone.
Inhibition of Autophagy Potentiates Atorvastatin-Induced Apoptotic Cell Death in Human Bladder Cancer Cells in Vitro (2014)

Statins are cholesterol reduction agents that exhibit anti-cancer activity in several human cancers. Because autophagy is a crucial survival mechanism for cancer cells under stress conditions, cooperative inhibition of autophagy acts synergistically with other anti-cancer drugs. Thus, this study investigates whether combined treatment of atorvastatin and autophagy inhibitors results in enhancing the cytotoxic effects of atorvastatin, upon human bladder cancer cells, T24 and J82, in vitro. To measure cell viability, we performed the EZ-Cytox cell viability assay. We examined apoptosis by flow cytometry using annexin-V/propidium iodide (PI and western blot using procaspase-3 and poly (ADP-ribose) polymerase (PARP) antibodies. To examine autophagy activation, we evaluated the co-localization of LC3 and LysoTracker by immunocytochemistry, as well as the expression of LC3 and p62/sequestosome-1 (SQSTM1) by western blot. In addition, we assessed the survival and proliferation of T24 and J82 cells by a clonogenic assay. We found that atorvastatin reduced the cell viability of T24 and J82 cells via apoptotic cell death and induced autophagy activation, shown by the co-localization of LC3 and LysoTracker. Moreover, pharmacologic inhibition of autophagy significantly enhanced atorvastatin-induced apoptosis in T24 and J82 cells. In sum, inhibition of autophagy potentiates atorvastatin-induced apoptotic cell death in human bladder cancer cells in vitro, providing a potential therapeutic approach to treat bladder cancer.
Thermal Plasma Processes for Production of Hollow Spherical Powders: Theory and Experiment (2011)

Present paper considers processes of production and treatment of hollow particles in plasma flows. Specifics of agglomerated powders treatment and expansion of hollow droplets are analyzed theoretically. Experimental results on production of hollow micro particles of ZrO2, Ni, CoNiCrAlY alloy, SiO2 are shown here.
Deviation saddles for cables bridges: development and qualification ofstay cable technology (2019)

&lt;p&gt;Deviation saddles for cables are regularly used in projects such as cable stayed bridges, suspended bridges or extradossed bridges. The choice of a deviation saddle may be imposed to improve the bridge aesthetics with a slender pylon and to simplify the construction with a solid pylon section. Saddles are a proper anchorage and must be designed such as to ensure a safe transfer of vertical forces and of differential forces of stay cables into the pylon structure.&lt;/p&gt;&lt;p&gt;For parallel strand cables, since grouted stay cable tends to disappear from commonly accepted design and technologies, due to corrosion protection and fatigue issues, the most widely used concept of saddle is made of a battery of individual tubes, placed inside a guide pipe poured of concrete.&lt;/p&gt;&lt;p&gt;The most recent saddle system developed consists in allowing the passage of the strands through the saddle without individual tubes. Strands go directly through concrete recesses within the Ultra High Performance Fiber Concrete (UHPFC) matrix. Recesses are made thanks to reusable rubber bars removed after poured concrete is hardened. Thanks to an optimized cross section of the recesses, individual holes maximize the friction between the concrete and specially sheathed strands with local application of a cohesive sheathing (Cohestrand®), which allow strands to transfer important asymmetrical loads to the saddle without sliding. Meanwhile, a continuous corrosion protection is ensured by the strand sheathing from one deck anchorage to the other.&lt;/p&gt;&lt;p&gt;This make the use of saddle a cost-effective and durable mean to deviate and anchor parallel strand cables, that suits Owners needing simple but robust design for stay cable or extradossed bridges. Such saddle bridge design is nowadays clearly described in the 7&lt;span&gt;th&lt;/span&gt;edition of the PTI recommendations, that specifies the qualification process of saddle technologies, especially in regards to the accurate definition of a minimum friction coefficient.&lt;/p&gt;
Compensation for readout noise in CCD images (1995)

Data acquired with a CCD camera are modeled as an additive Poisson–Gaussian mixture, with the Poisson component representing cumulative counts of object-dependent photoelectrons, object-independent photoelectrons, bias electrons, and thermoelectrons and the Gaussian component representing readout noise. Two methods are examined for compensating for readout noise. One method relies on approximating the Gaussian readout noise by a Poisson noise and then using a modified Richardson–Lucy algorithm to effect the compensation. This method has been used for restoring images acquired with CCD’s in the original Wide-Field/Planetary Camera aboard the Hubble Space Telescope. The second method directly uses the expectation-maximization algorithm derived for the Poisson–Gaussian mixture data. This requires the determination of the conditional-mean estimate of the Poisson component of the mixture, which is accomplished by the evaluation of a nonlinear function of the data. The second method requires more computation than the first but is more accurate mathematically and yields modest improvements in the quality of the restorations, particularly for fainter objects. As a specific example, we compare the two methods in restorations of images representative of those acquired with that camera; they contain excess blurring that is due to spherical aberration and a rms readout noise level of 13 electrons.
Proteotypic profiling of LHCI from Chlamydomonas reinhardtii provides new insights into structure and function of the complex (2009)

We used isotope dilution MS to measure the stoichiometry of light-harvesting complex I (LHCI) proteins with the photosystem I (PSI) core complex in the green alga Chlamydomonas reinhardtii. Proteotypic peptides served as quantitative markers for each of the nine gene products (Lhca1-9) and for PSI subunits. The quantitative data revealed that the LHCI antenna of C. reinhardtii contains about 7.5 +/- 1.4 subunits. It further demonstrated that the thylakoid LHCI population is heterogeneously composed and that several lhca gene products are not present in 1:1 stoichiometries with PSI. When compared with vascular plants, LHCI of C. reinhardtii possesses a lower proportion of proteins potentially contributing to far-red fluorescence emission. In general, the strategy presented is universally applicable for exploring subunit stoichiometries within the C. reinhardtii proteome.
Pneumococcal Septic Arthritis: Review of 190 Cases (2003)

This article reports 13 cases of pneumococcal septic arthritis and reviews another 177 cases reported since 1965. Of 2407 cases of septic arthritis from large series, 156 (6%) were caused by Streptococcus pneumoniae. Mortality was 19% among adults and 0% among children. Pneumococcal bacteremia was the strongest predictor of mortality. At least 1 knee was involved in 56% of adults. Polyarticular disease (36%) and bacteremia (72%) were more common among adults with septic arthritis caused by S. pneumoniae than among adults with other causative organisms. Only 50% of adults with pneumococcal septic arthritis had another focus of pneumococcal infection, such as pneumonia. Functional outcomes were good in 95% of patients. Uncomplicated pneumococcal septic arthritis can be managed with arthrocentesis and 4 weeks of antibiotic therapy; most cases of pneumococcal prosthetic joint infection can be managed without prosthesis removal. A fatal case of septic arthritis caused by a beta-lactam-resistant strain of S. pneumoniae is also presented.
Preterm Milk Oligosaccharides During the First Month of Lactation (2011)

Our data confirm lower lactose concentrations in preterm milk, compared with term milk, and they provide the first detailed characterization of oligosaccharides in preterm milk, demonstrating important differences in oligosaccharide contents in the 4 groups. These differences might exert an influence on several biological functions that are particularly important for preterm infants and currently are attributed to milk oligosaccharides.
Phthalic anhydride production from hemicellulose solutions: Technoeconomic analysis and life cycle assessment (2015)

The process synthesis, technoeconomic analysis, and life cycle assessment (LCA) of a novel route for phthalic anhydride (PAN) production from hemicellulose solutions are presented. The production contains six steps including dehydration of xylose to furfural, reductive decarbonylation of furfural to furan, oxidation of furfural to maleic anhydride (MA), Diels‐Alder cycloaddition of furan, and MA to exo −4,10‐dioxa‐tricyclo[5.2.1.0]dec‐8‐ene‐3,5‐dione followed by dehydration to PAN in the presence of mixture of methanesulfonic acid and acetic anhydride (AAN) which is converted to acetyl methanesulfonate and acetic acid (AAD), and dehydration of AAD to AAN. The minimum selling price of PAN is determined to be $810/metric ton about half of oil‐based PAN. The coproduction of high‐value products is essential to improve the economics. Biomass feedstock contributes to the majority of cost. LCA results shows that biomass‐based PAN has advantages over oil‐based PAN to reduce climate change and fossil depletion however requires more water usage. © 2015 American Institute of Chemical Engineers AIChE J , 61: 3708–3718, 2015
The Flow Topology of the Herzenberg Immunological Control Networks (2018)

This chapter examines the immunological control networks using topological and graph theoretical methods similar to those previously used for chemical reaction networks. It aims to extend the approach of Eisenfeld and DeLisi by considering the flow topologies rather than the stabilities of immunological control networks and treats the Herzenberg models rather than the models of Kaufman, Urbain, and Thomas. Topological models of immunological control networks provide guidance for much more complicated continuous analyses using specific systems of differential equations. An immunological control network, thus, can be represented by a bipartite graph. Conversion of an immunological control network into the corresponding influence diagram can require several stages if removal of a weak vertex and its associated edges converts a strong vertex into a weak vertex. The Herzenberg models for immunological control networks are well suited for the flow topological methods and lead to the locking in stable &quot;help&quot; and/or &quot;suppression&quot; configurations observed experimentally.
Efficient Attribute-Based Encryption with Privacy-Preserving Key Generation and Its Application in Industrial Cloud (2019)

Due to the rapid development of new technologies such as cloud computing, Internet of Things (IoT), and mobile Internet, the data volumes are exploding. Particularly, in the industrial field, a large amount of data is generated every day. How to manage and use industrial Big Data primely is a thorny challenge for every industrial enterprise manager. As an emerging form of service, cloud computing technology provides a good solution. It receives more and more attention and support due to its flexible configuration, on-demand purchase, and easy maintenance. Using cloud technology, enterprises get rid of the heavy data management work and concentrate on their main business. Although cloud technology has many advantages, there are still many problems in terms of security and privacy. To protect the confidentiality of the data, the mainstream solution is encrypting data before uploading. In order to achieve flexible access control to encrypted data, attribute-based encryption (ABE) is an outstanding candidate. At present, more and more applications are using ABE to ensure data security. However, the privacy protection issues during the key generation phase are not considered in the current ABE systems. That is to say, the key generation center (KGC) knows both of attributes and corresponding keys of each user. This problem is especially serious in the industrial big data scenario, because it will cause great damage to the business secrets of industrial enterprises. In this paper, we design a new ABE scheme that protects user’s privacy during key issuing. In our new scheme, we separate the functionality of attribute auditing and key generating to ensure that the KGC cannot know user’s attributes and that the attribute auditing center (AAC) cannot obtain the user’s secret key. This is ideal for many privacy-sensitive scenarios, such as industrial big data scenario.
Double-Gate Negative-Capacitance MOSFET With PZT Gate-Stack on Ultra Thin Body SOI: An Experimentally Calibrated Simulation Study of Device Performance (2016)

In this paper, we propose and investigate the high-performance and low-power design space of nonhysteretic negative capacitance (NC) MOSFETs for the 14-nm node based on the calibrated simulations using an experimental gate-stack with PZT ferroelectric to obtain the NC effect. All necessary parameters are extracted by carefully characterizing experimentally fabricated ferroelectric capacitors, to ensure realistic simulation results. The ferroelectric thickness obtained by the proposed approach leads to the maximum enhancement in the nonhysteretic operation of NC transistors. We report a clear and significant double improvement in: 1) subthreshold swing and 2) gate overdrive, using the NC effect. Simulations using Silvaco TCAD coupled with a realistic Landau model of ferroelectrics demonstrates that a 14-nm node ultrathin body and box fully depleted silicon-on-insulator FET can operate at 0.26 V instead of 0.9 V gate voltage using the NC effect, with an average subthreshold swing of 55 mV/decade at room temperature. The double-gate structure is proposed to overcome the large mismatch between the ferroelectric and MOS capacitor to enhance the NC effect and reduce the ferroelectric's optimized thickness. A 14-nm node double-gate negative capacitance FET can operate at 0.24 V gate voltage with an average subthreshold swing of 45 mV/decade.
Event-based state estimation with negative information (2013)

To reduce the amount of data transfer in networked systems, measurements are usually taken only when an event occurs rather than periodically in time. However, this complicates estimation problems considerably as it is not guaranteed that new sensor measurements will be sampled. In order to cope with such event sampled measurements, an existing state estimator is modified so that any divergent behavior in estimation results will be curtailed. To start, a general formulation of event sampling is proposed, which is then used to set up a state estimator combining stochastic as well as set-membership measurement information according to a hybrid update: when an event occurs the estimated state is updated using the stochastic measurement received (positive information), while at periodic time instants no new measurement is received (negative information) and the update is based on knowledge that the sensor value lies within a bounded subset of the measurement space. An illustrative example further shows that the developed estimator has an improved representation of estimation errors compared to purely stochastic estimators for various event sampling strategies.
Toward a vision based hand gesture interface for robotic grasping (2009)

The challenging problem of planning manipulation tasks for dexterous robotic hands can be significantly simplified if the robot system has the ability to learn manipulation skills by observing a human demonstrator. Toward this goal, we present a novel computer vision based hand posture recognition system to serve as an intelligent interface for skill transfer in robotic manipulation. We use the inner distance shape context (IDSC) as a hand shape descriptor to capture variations in the hand state (open or closed) under large in-plane rotations and considerable out-of-plane rotations. The proposed technique is further examined in applications involving grasp recognition and gesture based communications. The experiments show that the proposed approach can be generalized to recognizing a selected taxonomy of grasp types. At present, skin color is used to segment the hand region from the scene, but this method has its own limitations. We show preliminary results suggesting that the IDSC can be used to segment parts of the articulated object, including segmenting the hand from the human body silhouette without using skin color information.
Frequent hypermethylation of 5′ flanking region of TIMP‐2 gene in cervical cancer (2004)

Tissue inhibitor of metalloproteinase-2 (TIMP-2) is an endogenous inhibitor of matrix metalloproteinases (MMPs). This multifunctional protein regulates activities of MMPs and possesses growth promoting effect in cell culture, anti-tumoral, anti-apoptotic and anti-angiogenic effects in animal model systems in vivo. It has been shown that this gene is downregulated in cervical carcinomas. The mechanism of inhibition of TIMP-2 expression remains obscure. We have examined whether aberrant DNA methylation of the 5'CpG island of the TIMP-2 gene is involved in its inhibition during cervical carcinogenesis. Bisulfite-modified DNA sequencing and MSP assay showed aberrant methylation of TIMP-2 5'-CpG island in 17 of 36 (47%) invasive cervical carcinomas and in 2 of 3 cervical cancer cell lines. TIMP-2 gene was mostly unmethylated in the morphologically normal tissues adjacent to the tumors, whereas methylated alleles of this gene were found in 4 samples. Each tumor and each cell line DNA was characterized by unique methylation pattern, however a discrete region of TIMP-2 CpG island upstream to the transcription start site was densely methylated in all hypermethylated DNA samples examined. The expression of TIMP-2 mRNA can be restored in the cell lines, in which this discrete region of TIMP-2 CpG island is methylated, by treatment with demethylating agents, 5-azacytidine and 5-aza-2'-deoxycytidine. Our data suggest that the aberrant methylation of TIMP-2 favors the development of primary cervical tumors. We describe for the first time the aberrant hypermethylation of TIMP-2 gene in human cancer.
Planning for performance (1998)

A shift is proposed in the design of VLSI circuits. In conventional design, higher levels of synthesis produce a netlist, from which layout synthesis builds a mask specification for manufacturing. Timing analysis is built into a feedback loop to detect timing violations which are then used to update specifications to synthesis. Such iteration is undesirable, and for very high performance designs, infeasible. The problem is likely to become much worse with future generations of technology. To achieve a non-iterative design flow, we propose that early synthesis stages should use “wireplanning” to distribute delays over the functional elements and interconnect, and layout synthesis should use its degrees of freedom to realize those delays. In this paper we attempt to quantify this problem for future technologies and propose some solutions for a “constant delay” methodology.