gebhart/patrepeval huggingface dataset:
Automatic reconfiguration in Autonet (1991)

Autonet is a switch-based local area network using 100 Mbit/s full-duplex point-to-point links. Crossbar switches are interconnected to other switches and to host controllers in an arbitrary pattern. Switch hardware uses the destination address in each packet to determine the proper outgoing link for the next step in the path from source to destination. Autonet automatically recalculates these forwarding paths in response to failures and additions of network components. This automatic reconfiguration allows the network to continue normal operation without need of human intervention. Reconfiguration occurs quickly enough that higher-level protocols are not disrupted. This paper describes the fault monitoring and topology acquisition mechanisms that are central to automatic reconfiguration in Autonet.
Antibody‐Targeted Drug Delivery to Injured Arteries Using Layered Double Hydroxide Nanoparticles (2012)

Targeted local delivery of a nanoparticle-based, antibody-targeted, and low molecular weight heparin (LMWH) delivery system successfully reduces restenosis and thrombus formation in an animal model. An antibody recognizing cross-linked fibrin (XLF) D-dimer is successfully conjugated to layered double hydroxide nanoparticles. Use of the anti-XLF-conjugated LMWH-carrying layered double hydroxide nanoparticles shows successful targeting of the nanoparticles (red) to the injured artery wall (green), resulting in decreased neointimal thickening and thrombus formation.
Superposition Imaging for Three-Dimensionally Space-Invariant Point Spread Functions (2011)

In this paper, we propose an aberration compensation method using superposition imaging and inexpensive postprocessing. In the method, the focusing distance and optical axis position of an imaging system with aberrations are varied over certain ranges, and the resulting images are superposed to equalize the point spread function (PSF) within a three-dimensional region and remove space variance. A sharp image of an object with a large depth-of-field and field-of-view is then reconstructed by deconvolution of the superposed image using the effective three-dimensionally space-invariant PSF. The effectiveness of the proposed method was verified by simulations assuming defocus, the five Seidel aberrations, and vignetting.
Correlation between clinical severity and extent of autonomic cardiovascular impairment in the acute phase of subarachnoid hemorrhage (2022)

Within the acute phase, spontaneous SAH induces a decrease in sympathetic and total autonomic cardiovascular modulation. Higher H&H-scores were associated with increasing autonomic dysfunction and may therefore augment the risk of cardiovascular complications and poor clinical outcome.
In vivo quantification of ageing changes in the rat liver from early juvenile to senescent life (2002)

These age-associated physiological changes should be carefully taken into account as a relevant variable in experimental research.
The design and performance of a superfluid [sup 3]He-[sup 4]He compressor (2002)

A superfluid 3He-4He compressor, that utilizes a bellows piston design and low dissipation suction and discharge valves, has been developed at the Cryogenic Engineering Laboratory at MIT. This compressor has a superleak bypass around the suction valve, which allows the superfluid 4He part of the working fluid to flow freely out of the compressor when the valves are closed during the compression stroke. Since the 3He component of the mixture cannot flow through the superleak, the 3He concentration of the mixture increases during the compression process. This compressor is suitable for use in a new class of sub-Kelvin refrigerators including the superfluid Joule-Thomson refrigerator. The design and predicted performance of this compressor is presented.
Quantitative videographic analysis of intraoperative total shoulder arthroplasty is predictive of radiographic implant loosening (2018)

Our results indicate that surgeons could review surgical videos and differentiate the cases that were difficult or those that were more likely to lead to loosening of the glenoid component. The presence of a B2 glenoid was predictive of difficult surgery. The results of this study should serve as a starting point for surgeons interested in critically evaluating performance and also for those interested in finding ways to maximize patient outcomes after total shoulder arthroplasty.
Optimal Design of a Polyaniline-Coated Surface Acoustic Wave Based Humidity Sensor (2013)

This paper presents an optimal design for a new humidity sensor composed of a dual-resonator oscillator configuration with an operation frequency of 300 MHz, and a polyaniline (PANI) coating deposited along the resonation cavity of the sensing device. To improve the corrosion resistance of the sensor chip, Al/Au electrodes were used to form the SAW resonator. Prior to device fabrication, the coupling of modes (COM) model was used for the performance prediction and optimal design parameters determination. Two SAW resonators with Al/Au electrodes were fabricated on an ST-X quartz substrate, and used as the frequency control element in the feedback path of an oscillator circuit. A PANI thin coating was deposited onto the resonator cavity of the sensing device by a spinning approach as the sensor material for relative humidity (RH) detection. High detection sensitivity, quick response, good repeatability and stability were observed from the sensor experiments at room temperature.
Modeling variability and irreproducibility of nanoelectronic resistive switches for circuit simulation (2013)

This paper presents a device model for nanoelectronic resistive switches which are based on the electrochemical metallization effect (ECM). The focus is set on modeling variability as well as irreproducibility which are essential properties of scaled nanoelectronic devices. In particular, a Poisson-based random ion deposition model and a non-linear filament surface effect are described. The model is especially useful for circuit simulation and can be implemented on standard circuit simulation platforms such as Spice or Spectre using inbuilt standard elements. Based on this model, effects of variability were examined by Monte Carlo simulation for a particular hybrid CMOS/nanoelectronic circuit. The results show that the proposed model is able to cover significant scaling effects, which is necessary for prospective design space exploration and circuit optimization.
Metric details for natural-language spatial relations (1998)

Spatial relations often are desired answers that a geographic information system (GIS) should generate in response to a user's query. Current GIS's provide only rudimentary support for processing and interpreting natural-language-like spatial relations, because their models and representations are primarily quantitative, while natural-language spatial relations are usually dominated by qualitative properties. Studies of the use of spatial relations in natural language showed that topology accounts for a significant portion of the geometric properties. This article develops a formal model that captures metric details for the description of natural-language spatial relations. The metric details are expressed as refinements of the categories identified by the 9-intersection, a model for topological spatial relations, and provide a more precise measure than does topology alone as to whether a geometric configuration matches with a spatial term or not. Similarly, these measures help in identifying the spatial term that describes a particular configuration. Two groups of metric details are derived: splitting ratios as the normalized values of lengths and areas of intersections; and closeness measures as the normalized distances between disjoint object parts. The resulting model of topological and metric properties was calibrated for 64 spatial terms in English, providing values for the best fit as well as value ranges for the significant parameters of each term. Three examples demonstrate how the framework and its calibrated values are used to determine the best spatial term for a relationship between two geometric objects.
Delinquent Children (1949)

any form of sexual relation, even platonic.He knows that this is counsel of perfection, and thinks that legal penalties should attach only to actions corresponding to those for which normal men are punished.The frequency of inversion has probably been exaggerated through failure to distinguish it from bisexuality, and the author estimates that the percentage of inverts in the male population is not more than five.This figure may seem high, but lower estimates may be due to lack of skill on the observer's part.The author found no evidence for the opinion that seduction plays a significant part in causing inversion-an opinion reminiscent of the attribution of tumours to trauma.Of his more r'ecent findings, perhaps the most interesting is -that sexual attraction between inverts is extremely rare: a male invert almost invariably desires that his "mate" shall be a com- pletely normal man.The conclusion drawn is that " all psychosexual attraction is essentially heterosexual."The book leaves no doubt that sexual inversion is wholly involuntary or that most inverts-like most normal men-try to live decent and useful lives.This work will be helpful to specialists, whose knowledge of inversion may be based solely on clinical experience.To general practitioners-and indeed to all who have to deal with young people-it will be invaluable.
Molecular Alignments Studied by X-Ray Diffraction Analysis and Optical Properties of Vacuum-Deposited Thin Films of Thiophene–Pyridine Co-Oligomers (2006)

An X-ray diffraction study of vacuum-deposited films of thiophene–pyridine co-oligomers on a sapphire substrate indicated a perpendicular or perpendicular-like alignment of the co-oligomers on the surface of the substrate. The UV-vis peak of the vacuum-deposited films shifted to a shorter wavelength from that observed in solutions. The UV-vis data support the notion that the co-oligomer in the vacuum-deposited film assumes a twisted conformation.
A base-paired hairpin structure essential for the functional priming signal for DNA replication of the broad host range plasmid RSF1010 (1993)

The two single-strand DNA initiation signals, ssiA(RSF1010) and ssiB(RSF1010) of the broad host-range plasmid RSF1010 contain proposed stem-loop structures. Nine single base-change mutations in the stem of the ssiA structure, each of which destroyed a relevant base pairing, damaged the ssiA activity. A second single-base change was introduced into each of the nine ssiA mutants in such a way that the base pairing was restored. Only three out of nine second base changes that restored the base pairing restored the ssiA activity up to the wild-type level. Thus, the three are intramolecular suppressors. The results strongly suggested that, in the area of the stem of ssiA where the suppressor mutations fell, base pairing was the most important structural parameter for the ssiA activity. By contrast, it is most probable that, in the other part of the stem of ssiA, both base-pairing and the intrinsic base sequence were the major determinants of the ssiA activity.
Continuous-time delta-sigma modulator with maximally flat signal transfer function using minimum number of DACs (2017)

This paper presents a design methodology to achieve maximally flat signal transfer function (STF) in continuous-time delta-sigma modulators (CTDSMs). A 4 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">th</sup> order CTDSM with a chain of feedback (CIFB) structure is used to achieve maximally flat STF, while the required number of digital-to-analog converters (DACs) in the traditional CIFB structure is minimized. Therefore, both high in-band dynamic range and low power/area can be achieved by using the proposed scheme. Detailed Cadence and Matlab simulations are provided to prove the operation of the proposed scheme.
Advanced Pulmonary Hypertension Due to Congenital Double-shunt Successfully Treated with Surgical Repair and Up-front Combination Therapy (2019)

This case report concerns a 22-year-old woman with large patent ductus arteriosus and atrial septal defect. She was referred to our hospital because of exertional dyspnea and was revealed to have advanced pulmonary arterial hypertension (PAH) with a mean pulmonary arterial pressure (PAP) of 79 mmHg. Although both shunts had bidirectional flow, based on the results of acute pulmonary vasoreactive testing, one-stage surgical closure was performed followed by up-front combination therapy for post-operative pulmonary hypertensive crisis and residual PAH. At 14 months after the surgery, her symptoms were markedly improved, and her mean PAP had dramatically decreased to 13 mmHg.
Substitution of Nd with other rare earth elements in melt spun Nd2Fe14B magnets (2016)

This is a contemporary study of rapidly quenched Nd1.6X0.4Fe14B magnetic materials (where X= Nd, Y, Ce, La, Pr, Gd and Ho). A 20% substitution of the Nd component from Nd2Fe14B can bring about some commercial advantage. However, there will be some compromise to the magnetic performance. Light rare earth elements are definitely more abundant (Y, Ce, La) than the heavier rare earth elements, but when they are included in RE2Fe14B magnets they tend to lower magnetic performance and thermal stability. Substituting heavy rare earth elements (Gd, Ho) for Nd in Nd2Fe14B improves the thermal stability of magnets but causes a loss in magnet remanence.
Binary optics lights the way to new imaging sensors (1991)

Through advances in semiconductor miniaturization technology, micro-relief patterns with characteristic dimensions as small as the wavelength of light can now be mass produced. In a classic example of technology transfer, this capability is allowing optics designers—for the first time ever—to create innovative optical components that promise to solve key problems in optical sensors, communication channels, and optical processors.
Human papillomavirus type 16 and 18 gene expression in cervical neoplasias (1992)

Human papillomavirus (HPV) types 16 and 18 are strongly implicated in the generation of progressive cervical neoplasms. The viruses produce complex families of overlapping messenger RNAs that are linked to differentiation, making it necessary to analyze gene expression in the context of morphology. We have developed HPV type 16 and type 18 subgenomic clones from which 3H-labeled riboprobes specific to individual mRNA families can be generated in vitro. Using these probes for in situ hybridization, we examined serial sections of archival biopsy specimens of the spectrum of genital lesions. In low-grade squamous lesions, all viral open reading frames were expressed, and the most abundant transcription spanned the E4 and E5 open reading frames at the 3' end of the E region. L region transcription coding for the capsid proteins was restricted to terminally differentiated keratinocytes. As the grade of neoplasia increased, cellular differentiation and overall viral transcription decreased and, with few exceptions, the L2 and L1 transcripts ceased to exist. The E6-E7 transforming region was invariably derepressed. Interestingly, the patterns of HPV-16 gene expression suggested the coexistence of episomal and integrated viral DNAs. In contrast, in HPV-18 lesions, all the viral template DNA appeared to have integrated. Integration was deduced to have occurred near the boundary of the E1 and E2 open reading frames. Viral transcription patterns were similar in carcinomas in situ and in invasive carcinomas, regardless of the histologic cell types or the associated virus types, consistent with the notion that additional host gene alterations were necessary for progression. On the basis of viral gene expression in vivo and the E6 promoter regulation previously characterized in vitro, we discuss a molecular mechanism for HPV-associated carcinogenesis.
The cyclic nucleotide specificity of three cAMP receptors in Dictyostelium. (1992)

cAMP receptors mediate signal transduction pathways during development in Dictyostelium. A cAMP receptor (cAR1) has been cloned and sequenced (Klein, P., Sun, T. J., Saxe, C. L., Kimmel, A. R., Johnson, R. L., and Devreotes, P. N. (1988) Science 241, 1467-1472) and recently several other cAR genes have been identified (Saxe, C. L., Johnson, R., Devreotes, P. N., and Kimmel, A. R. (1991a) Dev. Genet. 12, 6-13; Saxe, C. L., Johnson, R. L., Devreotes, P. N., and Kimmel, A. R. (1991b) Genes Dev. 5, 1-8). We have expressed three receptor subtypes, cAR1, cAR2, and cAR3, in growing cells and have investigated their affinity and pharmacological specificity in a series of [3H]cAMP binding studies. In phosphate buffer, there were two affinity states of about 30 and 300 nM for cAR1 and 20 and 500 nM for cAR3 but no detectable affinity for cAR2. In the presence of 3 M ammonium sulfate, there was one affinity state of 4 nM for cAR1 and 11 nM for cAR2 and two affinity states of approximately 4 and 200 nM for cAR3. The relative affinities of 14 cyclic nucleotide derivatives were tested for each cAR in ammonium sulfate. These studies suggest a model (Van Haastert, P. J. M., and Kien, E. (1983) J. Biol. Chem. 258, 9636-9642) in which cAMP binds to all three receptor subtypes by maintaining hydrogen bond interactions at the N6 and O3' positions. Interactions at the exocyclic oxygens of cAMP varied between the receptors; cAR2 and cAR3 lacked a stereoselective interaction at the axial oxygen which was present in cAR1. The cleft, which binds the adenine ring of cAMP, was hydrophobic in cAR1 and cAR3 but relatively polar in cAR2. The analog specificity of cAR1 and cAR3 in phosphate buffer was similar to that measured in ammonium sulfate though the derivatives' relative affinity to cAMP was reduced. We conclude that these cAMP receptor subtypes can be distinguished by distinct pharmacological properties which will allow selective activation of each cAR during development.
Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer’s Disease (2022)

Abstract Alzheimer’s disease (AD) is the most common form of dementia, with cerebrospinal fluid (CSF) β-amyloid (Aβ), total Tau, and phosphorylated Tau providing the most sensitive and specific biomarkers for diagnosis. However, these diagnostic biomarkers do not reflect the complex changes in AD brain beyond amyloid (A) and Tau (T) pathologies. Here, we report a selected reaction monitoring mass spectrometry (SRM-MS) method with isotopically labeled standards for relative protein quantification in CSF. Biomarker positive (AT+) and negative (AT-) CSF pools were used as quality controls (QCs) to assess assay precision. We detected 62 peptides (51 proteins) with an average CV of ∼13% across 30 QCs and 133 controls (cognitively normal, AT), 127 asymptomatic (cognitively normal, AT+) and 130 symptomatic AD (cognitively impaired, AT+). Proteins that could distinguish AT+ from AT-individuals included SMOC1, GDA, 14-3-3 proteins, and those involved in glycolysis. Proteins that could distinguish cognitive impairment were mainly neuronal proteins (VGF, NPTX2, NPTXR, and SCG2). This demonstrates the utility of SRM-MS to quantify CSF protein biomarkers across stages of AD.
GPR Imaging for Deeply Buried Objects: A Comparative Study Based on FDTD Models and Field Experiments (2012)

Conventional use of Ground Penetrating Radar (GPR) is hampered by variations in background environmental conditions, such as water content in soil, resulting in poor repeatability of results over long periods of time when the radar pulse characteristics are kept the same. Target objects types might include voids, tunnels, unexploded ordinance, etc. The long-term objective of this work is to develop methods that would extend the use of GPR under various environmental and soil conditions provided an optimal set of radar parameters (such as frequency, bandwidth, and sensor configuration) are adaptively employed based on the ground conditions. Towards that objective, developing Finite Difference Time Domain (FDTD) GPR models, verified by experimental results, would allow us to develop analytical and experimental techniques to control radar parameters to obtain consistent GPR images with changing ground conditions. Reported here is an attempt at developing 20 and 3D FDTD models of buried targets verified by two different radar systems capable of operating over different soil conditions. Experimental radar data employed were from a custom designed high-frequency (200 MHz) multi-static sensor platform capable of producing 3-D images, and longer wavelength (25 MHz) COTS radar (Pulse EKKO 100) capable of producing 2-D images. Our results indicate different types of radar can produce consistent images.
Reviews of Reactive Intermediate Chemistry (2006)

PREFACE. CONTRIBUTORS. PART 1 REACTIVE INTERMEDIATES. 1. Tetrahedral Intermediates Derived from Carbonyl Compounds, Pentacoordinate Intermediates Derived from Phosphoryl and Sulfonyl Compounds, and Concerted Paths Which Avoid Them (J.P. Guthrie). 2. Silicon-, Germanium-, and Tin-Centered Cations, Radicals, and Anions (V.Y. Lee and A. Sekiguchi). PART 2 METHODS AND APPLICATIONS. 3. An Introduction to Time-Resolved Resonance Raman Spectroscopy and Its Application to Reactive Intermediates (D.L. Phillips, W.M. Kwok, and C. Ma). 4. Time-Resolved Infrared (TRIR) Studies of Organic Reactive Intermediates (J.P. Toscano). 5. Studies of the Thermochemical Properties of Reactive Intermediates by Mass Spectrometric Methods (P.G. Wenthold). 6. Reactive Intermediates in Combustion (J.K. Merle and C.M. Hadad). 7. Reactive Intermediates in Crystals: Form and Function (L.M. Campos and M.A. Garcia-Garibay). 8. The Chemical Reactions of DNA Damage and Degradation (K.S. Gates). 9. Conical Intersection Species as Reactive Intermediates (M.J. Bearpark and M.A. Robb). 10. Quantum Mechanical Tunneling in Organic Reactive Intermediates (R.S. Sheridan). INDEX.
Identification of a metallopeptidase with TOP-like activity inParacoccidioides brasiliensis, with increased expression in a virulent strain (2012)

Paracoccidioidomycosis (PCM), caused by the pathogenic fungus Paracoccidioides brasiliensis, is a systemic mycosis with severe acute and chronic forms. The pathology of PCM is not completely understood, and the role of proteases in the infection is not clearly defined. In this report, we describe a metallopeptidase activity in P. brasiliensis total and cytosolic protein extracts similar to that of mammalian thimet oligopeptidase (TOP). The analogous enzyme was suggested by analysis of P. brasiliensis genome databank and by hydrolytic activity of the FRET peptide Abz-GFSPFRQ-EDDnp which was completely inhibited by o-phenanthrolin and significantly inhibited by the TOP inhibitor, JA-2. This activity was also partially inhibited by IgG purified from patients with PCM, but not from normal individuals. As shown by high-performance liquid chromatography (HPLC), the hydrolysis of bradykinin had the same pattern as that of mammalian TOP, and anti-mammalian TOP antibodies significantly inhibited fungal cytosolic peptidase activity. Moreover, anti-mammalian TOP antibodies recognized a component of 80 kDa on fungal cytosol. A P. brasiliensis virulent isolate showed higher gene expression and TOP-like peptidase activity than a non-virulent strain. The release of enzyme following fungal lysis would be consistent with host antibody production and may have a role in the pathogenesis, inflammation and further development of the mycosis.
The I2C Bus: From Theory to Practice (1997)

From the Publisher:
Using the world of micro-controller-managed serial buses, this user-friendly guide offers comprehensive coverage of the theory essential to design the best possible communications bus for any application. Describes typical industrial and consumer applications and provides examples of modular solutions at various levels of complexity as well as complete circuit diagrams. The accompanying disk contains software for the I2C bus.
Session details: Session 2a: (i can't get no) satisfaction (2014)

No abstract available.