gebhart/patrepeval huggingface dataset:
Surgical Management of an Externally Protruding, Perforating Intraocular Foreign Body (2018)

Ru-ik Chee Felix Y. Chau In this case of a perforating eye injury by a 2-inch-long nail that went through the cornea, lens, and posterior eye wall, the authors describe a combined external, anterior, and posterior segment surgical approach that resulted in safe and successful removal of the foreign body. Initial external trimming of the protruding nail facilitated the use of a noncontact viewing system. Combined limbal and pars plana placement of the vitrectomy cannulas optimized access to both anterior and posterior intraocular structures. Most importantly, careful removal of potential sources of foreign body adhesion to intraocular structures prior to extraction likely increased the likelihood for a successful clinical outcome. Care was taken to remove as much of the vitreous as possible and to keep the eye formed. The patient recovered 20/25+2 vision with aphakic correction.
Exon Array Analysis to Identify Diethyl-nitrosamine Differentially Regulated and Alternately Spliced Genes in Early Liver Carcinogenesis in the Transgenic Mouse ATT-myc Model (2021)

Objectives: To identify the regulated genes or the spliced genes of diethylnitorsamine (NDEA) in ATT-myc mice versus control group. Methods: We analysed the 9 hybridizations on the MouseExon10ST array of NDEA treatments and control non- transgenic by application of a mixed model analysis of variance. Results: The 907 genes had regulated significantly between the groups and 916 genes had regulated with a significant exon-group interaction among of them 150 genes had regulated with both gene and possible splicing differences (p&lt;0.01). The 7,618 genes had tested for the alternative gene up-regulation and splicing and compared to the gene-classifications. The genes functions, pathways and gene-classifications in the current study had presented in the contingency table analysis of the set of the regulated genes and alternatively spliced that regulated significantly in the ATT-myc mice treated by diethylnitorsamine versus control non-transgenic. The GOMolFn of gene-classification had 321 groups that had significantly regulated in the set of the regulated genes or differentially spliced. While the GOProcess of gene-classification had 330 groups that had significantly regulated in the set of differentially regulated genes or spliced. Additionally, the CELlLoc of gene-classification had 70 groups that had significantly regulated in the set of differentially regulated genes spliced. Finally, the Pathway gene-classification had 8 groups that had significantly regulated in the set of differentially regulated genes or spliced (p&lt;0.01) in diethylnitorsamine when compared to control group. Conclusion: we summarized the toxicogenomics induced by diethylnitrosamine in early liver carcinogenesis in ATT-myc transgenic mice of liver cancer. Doi: 10.28991/SciMedJ-2021-0302-6 Full Text: PDF
Component feature-based digital waveform analysis and classification (1996)

In the past few decades, digital pattern recognition has developed into a widely practiced field with multidisciplinary applications. However, the computational complexity of a digital pattern recognition system depends on the number of input measurement features. Since, this number can be large in many applications, it is desirable to develop a digital recognition technique that utilizes only those measurement features that include the most important information within a given object.
The objective of the thesis research is to design a component feature-based unsupervised digital pattern recognition system, which includes statistical and neural network approaches, and its applications to digital waveform analysis and classification from a digital air monitor. The use of unsupervised digital pattern recognition techniques to carry out the component features (principal component features, canonical discriminant features and optimal declustering features) allows for the substitution of high-dimensional measurement features with low-dimensional components, while minimizing the information lost. A component feature-based unsupervised digital pattern recognition system can simplify the structure of the covariance to make visual interpretation of cluster graphs more straightforward and to assess the results of cluster performance. Moreover, the performance of the component feature-based statistical and neural network classifiers does not degrade compared with the multidimensional feature-based statistical classification system and neural network system, while the efficiency of computational complexity and the storage of data memory is significantly improved. These properties are particularly important in real-time analysis of any digital signal sources sampled at extremely high-speed A/D conversion.
In this thesis, we also address the overlaid technique based on a hidden Markov model for the multiple digital waveform analysis. The goal of this technique is to investigate the possibility to identify the different groups of digital waveform classes and to calculate their energies without having to determine the individual digital waveform. These are shown by the comprehensive results obtained from practical applications of the system. In conclusion, these techniques are quite versatile and are likely to be very useful in many multidimensional digital signal analysis and pattern recognition applications. The application of these techniques is novel and also appears to be novel.
An Adaptive Feed-Forward Controller for Active Wing Bending Vibration Alleviation on Large Transport Aircraft (2009)

Particularly on large transport aircraft the first wing bending mode is significantly excited by atmospheric turbulence. Based on flight test data, it is shown that the related modal accelerations can be compensated very efficiently by feed-forward control. In order to increase the robustness of the control performance against plant uncertainties, an adaptive algorithm is designed for said feed-forward control. Moreover, the stability of the adaptation is analysed. Finally, the implementation of the proposed adaptive feed-forward controller is demonstrated in a wind tunnel experiment.
In Situ Identification of Intracellular Bacteria Related to Paenibacillus spp. in the Mycelium of the Ectomycorrhizal Fungus Laccaria bicolor S238N (2003)

Bacterial proliferations have recurrently been observed for the past 15 years in fermentor cultures of the ectomycorrhizal fungus Laccaria bicolor S238N, suggesting the presence of cryptic bacteria in the collection culture of this fungus. In this study, intracellular bacteria were detected by fluorescence in situ hybridization in combination with confocal laser scanning microscopy in several collection subcultures of L. bicolor S238N. They were small (0.5 micro m in diameter), rare, and heterogeneously distributed in the mycelium and were identified as Paenibacillus spp. by using a 16S rRNA-directed oligonucleotide probe initially designed for bacteria isolated from a fermentor culture of L. bicolor S238N.
Diagnosis of primary breast carcinoma through immunohistochemical detection of antigen related to mouse mammary tumor virus in metastatic lesions: A report of two cases (1982)

Recent investigations have established that approximately half of human breast carcinomas contain an immunohistochemically detectable antigen which is cross-reactive with the 52000-dalton major glycoprotein (gp52) of the mouse mammary tumor virus (MMTV). This antigen can be localized in paraffin-embedded sections of routinely fixed tissues using heterologous antibodies to gp52 or MMTV. This report describes two patients with metastatic carcinoma in axillary lymph nodes without any clinical evidence of a primary lesion in the breast or elsewhere. The localization of the gp52-related antigen in paraffin-embedded sections of both metastatic lesions suggested the presence of primary mammary carcinoma. In both instances, this suggestion was ultimately confirmed by the finding of primary lesions in which the gp52-related antigen was also found.
A wearable thermoelectric generator fabricated on a glass fabric (2014)

The conversion of body heat into electrical energy using a thermoelectric (TE) power generator is useful for wearable self-powered mobile electronic systems such as medical sensors or smart watches. We herein demonstrate a glass fabric-based flexible TE generator using a screen printing technique and the self-sustaining structure of a TE device without top and bottom substrates. With this technique it is possible to make the device thin (∼500 μm), lightweight (∼0.13 g cm−2), and flexible. In addition, the developed TE generator achieved an unprecedentedly large output power density which is several tens of times higher than that of flexible TE generators reported to date. The developed TE generator shows an allowable bending radius of as low as 20 mm and no change in performance by repeated bending for 120 cycles. This work can expedite the development of wearable self-powered mobile devices.
Association of sialyl-Lewis(a) and sialyl-Lewis(x) with MUC-1 apomucin ina pancreatic cancer cell line. (1995)

We have shown previously that the mucins of the human pancreatic cancer cell line, SW1990, have both sialyl-Lewis(a) and sialyl-Lewis(x) carbohydrate ligands that are implicated in tumor cell metastasis. In the present study, we undertook to identify the protein core of these mucins. SW1990 mucins that carry sialyl-Lewis(a) and sialyl-Lewis(x) bound to the MUC1 peptide-specific mAb 139H2. Removal of most of the sialic acids from SW1990 mucins by neuraminidase greatly enhanced binding of two other MUC1 peptide specific antibodies, HMFG-2 and SM-3. After removal of sialic acids, most of the mucins rich in sialyl-Lewis(a) and sialyl-Lewis(x) oligosaccharides no longer bound to a DEAE-cellulose column at pH 8.0. These results indicate that at least part of the sialyl-Lewis(a) and sialyl-Lewis(x) in SW1990 cells is associated with the MUC1 polypeptide. Moreover, sialic acids play an important role in determining the net negative charge of sialyl-Lewis(a) and sialyl-Lewis(x) rich mucins and in obscuring MUC1 peptide regions.
Analysis of Transient Cavitating Flows in Diesel Injectors Using Diesel and Biodiesel Fuels (2010)

&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;The aim of the paper is the comparison of the injection process with different fuels, i.e. a standard diesel fuel and a pure biodiesel. Multiphase cavitating flows inside diesel nozzles are analyzed by means of unsteady CFD simulations using a two-fluid approach with consideration of bubble dynamics, on moving grids from needle opening to closure. Two five-hole nozzles with cylindrical and conical holes are studied and their behaviors are discussed taking into account the different properties of the two fuels. Extent of cavitation regions is not much affected by the fuel type. Biodiesel leads to significantly higher mass flow only if the nozzle design induces significant cavitation which extends up to the outlet section and if the injector needle is at high lift. If the internal hole shaping is able to suppress cavitation, the stabilized mass flows are very similar with both fuels. On the contrary, as long as the lifts are small and the flow is turbulent, diesel fuel gives higher mass flows due to lower frictions along the needle seat and the nozzle walls. Detailed analyses of the injection processes are presented, including flow pattern development inside the nozzles.&lt;/div&gt;&lt;/div&gt;
SURF imaging: In vivo demonstration of an ultrasound contrast agent detection technique (2008)

A dual-band method for ultrasound contrast agent detection is demonstrated in vivo in an animal experiment using pigs. The method is named Second -order UltRasound Field Imaging, abbreviated SURF Imaging. It relies on simultaneously transmitting two ultrasound pulses with a large separation in frequency. Here, a low-frequency pulse of 0.9 MHz is combined with a high-frequency pulse of 7.5 MHz. The low-frequency pulse is used to manipulate the properties of the contrast agent, and the high frequency pulse is used for high-resolution contrast detection and imaging. An annular array capable of transmitting the low- and high-frequency pulses simultaneously was constructed and fitted to a mechanically scanned probe used in a GE Vingmed System 5 ultrasound scanner. The scanner was modified and adapted for the dual-band transmit technique. In-house software was written for post-processing of recorded IQ-data. Contrast-processed B-mode images of pig kidneys after bolus injections of 1 mL of Sonovuer are presented. The images display contrast detection with contrast-to-tissue ratios ranging from 15-40 dB. The results demonstrate the potential of SURF Imaging as an ultrasound contrast detection technique for clinically high ultrasound frequencies. This may allow ultrasound contrast imaging to be available for a wide range of applications.
Cell plasticity in wound healing: paracrine factors of M1/ M2 polarized macrophages influence the phenotypical state of dermal fibroblasts (2013)

Paracrine factors of M1 or M2 polarized macrophages induced different phenotypes of HDFs and the HDF phenotypes can in turn be reversed, pointing to a high dynamic plasticity of fibroblasts in the different phases of tissue repair.
Avant‑propos (1990)

« Le propre d’un travail scientifique étant de faire sortir l’ordre du chaos, il faut commencer par établir la réalité de ce chaos et par le décrire minutieusement. »Robert Cresswell. « De toutes les illusions, la plus périlleuse consiste à penser qu’il n’existe qu’une seule réalité. »Paul Watzlawick Cet ouvrage inaugure la publication des recherches archéologiques réalisées dans le défilé de Donzère. Il concerne la Baume des Anges dont le remplissage protohistorique fut étudié entre 1966 et ...
A solution to student‐faculty mismatch (1991)

Abstract Two geographically diverse WAC programs succeed in staff development because of good design and consistent administrative support.
The Candystrip Locus, <italic>y-cs</italic>, Determines Mutable Pigmentation of the Sorghum Leaf, Flower, and Pericarp (1994)

Several sorghum [Sorghum bicolor(L.) Moench] lines that exhibit variegated pericarp color have been collected. We selected one of these lines, referred to as candystripe, for genetic characterization. We found that the gene involved in the candystripe phenotype is not only associated with red pigment variegation in the pericarp layer of the seed, but also determines variegated red pigmentation in chlorophyll-bleached leaves and yellow pigmentation in the stigmas of mature flowers. Inheritance tests indicated that the candystripe trait is monogenic, and allelism tests showed that it is encoded by an allele of the sorghum Y locus, which we call y-cs. Segregation studies suggested that y-cs instability is autonomous and without extreme dosage effects. Molecular and mapping data demonstrated that the Y gene of sorghum is not homologous to any of the several(> 12) cloned genes from maize that are known to be involved in flavonoid synthesis. We have observed germinal instability of y-cs; apparent reversion to a stable Y phenotype occurred at frequencies varying from < 1% to > 20%. The behaviors of y-cs are indicative of the type of transposable element-induced systems that, in maize and other plant species, have proved invaluable as tools for molecular, genetic, and developmental studies.
Microwave-Assisted Self-Propagating Combustion Synthesis for Uniform Deposition of Metal Nanoparticles on Ceramic Monoliths (2009)

A new microwave-assisted gel-combustion synthesis in self-propagating mode was developed for the deposition of adhesive metal nanoparticles on ceramic substrates. Pt particles with diameters less than 10 nm uniformly distributed on corundum foams were prepared by the fast and reliable combustion method with no additional calcination or reduction steps. The results are rationalized in terms of complexation of the Pt precursor by glycerol, reduction of the Pt precursor to colloidal Pt nanoparticles, followed by carburization of the organic ligands and rapid carbon burn off preserving the high dispersion and uniformity of the Pt nanoparticles on the foam support.
Alicyclobacillus hesperidum sp. nov. and a related genomic species from solfataric soils of São Miguel in the Azores. (2000)

Several acidophilic, slightly thermophilic or thermophilic Gram-positive isolates were recovered from solfataric soil at Furnas on the Island of São Miguel in the Azores. Phylogenetic analysis of the 16S rRNA gene sequence showed that these organisms represented two novel species of the genus Alicyclobacillus. Strains FR-11T and FR-1b had an optimum growth temperature of about 50 degrees C, whereas strains FR-3 and FR-6T had an optimum growth temperature of about 60 degrees C. Biochemical, physiological and chemotaxonomic characteristics did not distinguish isolates FR-3 and FR-6T from the type strain of Alicyclobacillus acidocaldarius; however, strains FR-11T and FR-1b could be easily distinguished from the type strain of Alicyclobacillus acidoterrestris by the carbon source assimilation pattern and the fatty acid composition. On the basis of the phylogenetic analysis, physiological and biochemical characteristics, and fatty acid composition the name Alicyclobacillus hesperidum is proposed for the species represented by strains FR-11T and FR-1b; a formal name for the new genomic species represented by strains FR-3 and FR-6T is not proposed at this time.
Nanocomposite Coatings for Biomedical Applications (2010)

New electrochemical deposition methods have been developed for the fabrication of advanced composite coatings for biomedical applications. The methods are based on electrodeposition of biopolymers, such as cathodic electrodeposition of chitosan, anodic electrodeposition of alginic acid and hyaluronic acid. Another approach is based on anodic electropolymerization of polypyrrole. Electrochemical strategies have been discovered for the electrochemical co-deposition of polymers with other functional biomaterials, such as proteins, drugs, bioactive ceramics and bioglass. Bovine serum albumin was used as a model protein for the development of new electrochemical strategies for the fabrication of composite coatings containing proteins. New strategies have been further utilized for the fabrication of novel composites containing hemoglobin. It was found that biopolymers can be used for efficient electrosteric dispersion of bioceramics and bioglass in suspensions. Co-deposition of biopolymers with bioceramics and bioglass from the suspensions resulted in the fabrication of composite organic-inorganic bone substitute materials.<br /> Electrochemical methods have been developed for the deposition of composite coatings containing functional biomaterials in the matrix of conductive polypyrrole. New additives have been developed for the deposition of polypyrrole on low cost stainless steel substrates. The additives enabled the passivation of the stainless steel substrates and charge transfer during anodic electropolymerization. The composite coatings were obtained as monolayers, multilayers or materials of graded composition. <br /> The composition and microstructure of the composite coatings were investigated. The composition of these nanocomposite coatings can be varied by variation in bath composition for electrodeposition. The deposition yield was studied at various deposition conditions. Electrochemical deposition mechanisms have been investigated and discussed. Obtained results pave the way for the fabrication of novel coatings for the surface modification of biomedical implants and for application in advanced biosensors.
Inositol 1,4,5‐trisphosphate receptors: Immunocytochemical localization in the dorsal cochlear nucleus (1995)

In the cochlear nucleus of mammals, the relatively homogeneous responses of auditory nerve fibers are transformed into a variety of different response patterns by the different classes of resident neurons. The spectrum of these responses is hypothesized to depend on the types and distribution of receptors, ion channels, G proteins, and second messengers that form the signaling capabilities in each cell class. In the present study, we examined the immunocytochemical distribution of the inositol 1,4,5-triphosphate (IP3) receptor in the dorsal cochlear nucleus to better understand how this second messenger might be involved in shaping the neural signals evoked by sound. Affinity-purified polyclonal antibodies directed against the IP3 receptor labeled a homogeneous population of neurons in the dorsal cochlear nucleus of rats, guinea pigs, mustache bats, cats, New World owl monkeys, rhesus monkeys, and humans. These cells were all darkly immunostained except in the human where the labeling was less intense. Immunoblots of dorsal cochlear nucleus tissue from the rat revealed a single band of protein of molecular weight approximately 260 kD, which is the same size as the purified receptor, indicating that our antibodies reacted specifically with the IP3 receptor. These immunolabeled neurons were identified as cartwheel cells on the basis of shared characteristics across species, including cell body size and distribution, the presence of a highly invaginated nucleus, and a well-developed system of cisternae. Reaction product was localized along the membranes of rough and smooth endoplasmic reticulum, subsurface cisternae, and the nuclear envelope. This label was distributed throughout the cartwheel cell body and dendritic shafts but not within dendritic spines, axons, or axons terminals. The regular pattern of immunolabeling across mammals suggests that IP3 and cartwheel cells are conserved in evolution and that both play an important but as yet unknown role in hearing.
The AOST miniature Fourier spectrometer for space studies (2009)

The AOST Fourier spectrometer being developed for the Phobos-Soil project is intended for remote probing in the 2.5–25-μm region. This spectral region includes not only reflected and transmitted solar radiation, but also the intrinsic thermal radiation of the celestial body being studied. The maximum spectral resolution, taking into account apodization, is 0.9cm−1, and the field-of-view angle is 2.5°. The device has its own thermal-stabilization and two-axis guidance systems, as well as an absolute-blackbody simulator for calibration. The time to record one interferogram ranges from 5to50sec. The mass of the device is 4kg, and its power requirement is as much as 10W.
Cell culture of small round cell tumor originating in the thoracopulmonary region. Evidence for derivation from a primitive pluripotent cell (1989)

The authors describe a 14-year-old girl with small round cell tumor originating in the chest wall analyzed by the extensive studies including light and electron microscopic examination, histochemical study, immunochemical study, cytogenetics, and gene analysis. A cell line producing carcinoembryonic antigen (CEA) and neuron-specific enolase (NSE) has been established from pleural effusion of the pulmonary metastatic tumor. Cytogenetic analysis disclosed a reciprocal translocation (11;22)(q24;q12). Additionally, immunocytochemical studies demonstrated that CEA, NSE, vimentin, cytokeratin, and epithelial membrane antigens are positive, but desmin and S-100 protein are negative. Although neurofilament was negative in the pulmonary metastatic tumor cells, it became positive in cell line in vitro. These results suggest that this tumor may be derived from the primitive and pluripotential cells, differentiating into mesenchymal, epithelial, and neural features in variable proportions.