gebhart/patrepeval huggingface dataset:
Design of high sensitivity, high resolution compact single photon imaging devices for small animal and dedicated breast imaging (2005)

Imaging the biodistribution of single photon emitting radiotracers in small animals and in the breast with high resolution and high sensitivity is an important challenge. Recent work has shown that single photon emission computed tomography (SPECT) imaging of small objects with coded aperture collimators and iterative image reconstruction may provide an order of magnitude increase in sensitivity yet maintain high spatial resolution. We propose a new system design with compact detectors for single photon small animal and breast imaging. Key features are: 1) multipinhole masks for improved sensitivity, 2) pixellated NaI(Tl) scintillator arrays with small crystals for high resolution and 3) flat panel or flangeless compact position sensitive photomultiplier tubes. Analyses for a small animal device with four 10 cm/spl times/20 cm detectors and 1.5 mm detector resolution show that 0.9-1.3 mm resolution in image space could be achieved with high sensitivity for pinholes with 0.5-0.8 mm effective diameters. A design for a breast imager incorporates larger multipinhole masks, 20 cm/spl times/20 cm pixellated detectors and lower magnification. A predicted image resolution in the center of the field of view is 1.9 mm for 0.8 mm pinholes. Additional modeling, iterative image reconstruction tests and device component tests are desirable to optimize device specifications prior to detector construction.
Stimulation of the primary mixed leukocyte reaction. (1985)

This article will review the evidence that dendritic cells are specialized stimulator cells for the mixed leukocyte reaction. The topics to be considered are (1) identification of dendritic cells, (2) specialized stimulating capacity of dendritic cells in the allogeneic and syngeneic mixed leukocyte reactions, (3) stimulator cells for the secondary mixed leukocyte reaction, and (4) evidence for a role of dendritic cells during graft rejection in situ.
Adobe Integrated Runtime on Mobile Devices (2009)

The continuing trend is for mobile devices to become as capable as our desktop ones. Additionally, Adobe Integrated Runtime (AIR) availability on mobile devices is expected to increase thanks to the commitment of Adobe partners such as Intel and ARM to release more mobile devices that support AIR.KeywordsMobile DeviceGraphic Processing UnitCertificate AuthorityColor CorrectionEvent HandlerThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
In Situ Formation of Polysulfonamide Supported Poly(ethylene glycol) Divinyl Ether Based Polymer Electrolyte toward Monolithic Sodium Ion Batteries (2016)

Sodium ion battery is one of the promising rechargeable batteries due to the low-cost and abundant sodium sources. In this work, a monolithic sodium ion battery based on a Na<sub>3</sub> V<sub>2</sub> (PO<sub>4</sub> )<sub>3</sub> cathode, MoS<sub>2</sub> layered anode, and polyether-based polymer electrolyte is reported. In addition, a new kind of polysulfonamide-supported poly(ethylene glycol) divinyl ether based polymer electrolyte is also demonstrated for monolithic sodium ion battery via in situ preparation. The resultant polymer electrolyte exhibits relatively high ionic conductivity (1.2 mS cm<sup>-1</sup> ) at ambient temperature, wide electrochemical window (4.7 V), and favorable mechanical strength (25 MPa). Moreover, such a monolithic Na<sub>3</sub> V<sub>2</sub> (PO<sub>4</sub> )<sub>3</sub> /MoS<sub>2</sub> sodium ion battery using this polymer electrolyte delivers outstanding rate capability (up to 10 C) and superior cyclic stability (84%) after 1000 cycles at 0.5 C. What is more essential, such a polymer electrolyte based soft-package monolithic sodium ion cell can still power a red light emitting diode lamp and run finite times without suffering from any internal short-circuit failures, even in the case of a bended and wrinkled state. Considering these aspects, this work no doubt provides a new approach for the design of a high-performance polymer electrolyte toward monolithic sodium ion battery with exceptional rate capability and high safety.
Stabilization of p‐Block Organoelement Terminal Hydroxides, Thiols, and Selenols Requires Newer Synthetic Strategies (2004)

Metal hydroxides represent a very interesting and highly useful class of compounds that have been known to chemists for a very long time. While alkali and alkaline earth metal hydroxides (s-block) are commonplace chemicals in terms of their abundance and their use in a chemical laboratory as bases, the interest in Brønsted acidic molecular terminal hydroxides of p-block elements, such as aluminum and silicon, has been of recent origin, with respect to the variety of applications these compounds can offer both in materials science and catalysis. Moreover, these systems are environmentally friendly, relative to the metal halides, owing to their -OH functionality (resembling that of water). Design and conceptualization of the corresponding terminal thiols, selenols, and tellurols (M-SH, M-SeH, and M-TeH) offer even more challenging problems to synthetic inorganic chemists. This concept summarizes some of the recent strategies developed to stabilize these otherwise very unstable species. The successful preparation of a number of silicon trihydroxides a few years back resulted in the generation of several model compounds for metal-silicates. The recent synthesis of unusual aluminum compounds such as RAl(OH)(2), RAl(SH)(2), and RAl(SeH)(2) with terminal EH (E=O, Se, or Se) groups is likely to change the ways in which some of the well-known catalytic conversions are being carried out. The need for very flexible and innovative synthetic strategies to achieve these unusual compounds is emphasized in this concept.
Attitudes towards a Compassion Focus Therapy Group for Psychosis: A Survey of Service Users and Clinicians (2023)

Introduction The Living Through Psychosis (LTP) programme at St Patrick’s Mental Health Services, Ireland (SPMHS) is heavily informed by the Compassion Focus Therapy (CFT) for Psychosis model. LTP offers an opportunity for service users to develop compassion skills to cope with emotional and psychological challenges relating to living with psychosis; and to develop their capacity to for a mindful, non-judgemental and compassionate awareness of distressing thoughts and images. Objectives This (ongoing) online survey explores both service user and clinician attitudes towards the CFT-informed LTP group. We also aim to identify any potential concerns that might demotivate referrals to LTP and similar programmes, and to explore what are judged to be its benefits. The study also provides an opportunity to develop and improve the LTP programme to best fulfil service users’ needs. Methods The online survey is concise and responses are anonymous. Clinicians and service users complete similar-but-separate sets of questions that are adapted for relevancy and wording. The survey mainly consists of Likert Scale questions in relation to potential participation in, or referral to, LTP (after a visually-aided description of LTP is provided online within the survey). Using convenience sampling, the survey has been distributed among clinicians and service users through email and Internet advertisements within SPMHS and psychosis organisations such as Psychosis Ireland. Descriptive analysis is used for quantitative questions, while thematic analysis covers qualitative questions. Results Data collection is currently ongoing and will finish in December 2022. Preliminary results will be presented at the conference. Conclusions Conclusions will be derived from the results. It is anticipated that the findings will be helpful in further developing the LTP programme and similar CFT programmes for psychosis. Disclosure of Interest None Declared
Compiler support for memory management with explicit memory reclamation (2008)

Memory management plays a key role in the performance and reliability of modern software systems. Manual memory management (in languages such as C and C++) allows programmers to reclaim data in their programs in an efficient and predictable manner. However, manually reclaiming memory is error-prone and difficult to debug using traditional program testing. On the other hand, automatic memory reclamation via garbage collection (in languages such as Java, C#, or ML) eliminates memory errors, but can introduce program pauses and runtime overhead that can be unsuitable for some programs, such as embedded applications with real-time constraints. 
This thesis describes compiler techniques to support and improve safe memory management, both in programs that have explicit memory reclamation (C) and in programs that do not (Java). For the former, we present a tool that helps programmers debug memory errors by statically detecting common programming mistakes, such as memory leaks and double frees. For the latter, we study a variety of compiler analyses and transformations that insert memory deallocation code. This approach is automatic, ensures memory safety, is likely to incur little run-time overhead, and provides real-time guarantees. 
The proposed analysis technology is valuable in a larger context that goes well beyond the scope of memory management. Analysis clients such as program understanding tools, debugging tools, or other compiler transformations could greatly benefit from the information that our analyses extract, such as the lightweight method summaries or the reference uniqueness information. 
This thesis formalizes our analysis techniques and presents theoretical and experimental results. We show that our error-detection tool for C has found more than 60 memory leaks in standard benchmarks and open source applications. We also show that our compile-time memory reclamation techniques for Java can reduce program's memory utilization by half. They can also reduce memory management's runtime overhead by 30% when combined with garbage collection.
Message from the program chair (2016)

I would like to welcome you to ISPASS 2016, in Uppsala, Sweden. A total of 77 papers were submitted and were considered for the Technical Program. From these, 28 were selected as full papers, and 11 as posters. For those papers not accepted, we hope that the technical reviews we provided will prove helpful for future revisions. I thank all authors who submitted their work for consideration.
Highly Biased Type 1 Immune Responses in Mice Deficient in LFA-1 in Listeria monocytogenes Infection Are Caused by Elevated IL-12 Production by Granulocytes (2003)

LFA-1 (CD11a/CD18) plays a key role in various inflammatory responses. Here we show that the acquired immune response to Listeria monocytogenes is highly biased toward type 1 in the absence of LFA-1. At the early stage of listeriosis, numbers of IFN-gamma producers in the liver and spleen of LFA-1(-/-) mice were markedly increased compared with heterozygous littermates and Valpha14(+)NKT cell-deficient mice, and NK cells were major IFN-gamma producers. Numbers of IL-12 producers were also markedly elevated in LFA-1(-/-) mice compared with heterozygous littermates, and endogenous IL-12 neutralization impaired IFN-gamma production by NK cells. Granulocyte depletion diminished numbers of IL-12 producers and IFN-gamma-secreting NK cells in the liver of LFA-1(-/-) mice. Granulocytes from the liver of L. monocytogenes-infected LFA-1(-/-) mice were potent IL-12 producers. Thus, in the absence of LFA-1, granulocytes are a major source of IL-12 at the early stage of listeriosis. We assume that highly biased type 1 immune responses in LFA-1(-/-) mice are caused by increased levels of IL-12 from granulocytes and that granulocytes play a major role in IFN-gamma secretion by NK cells. In conclusion, LFA-1 regulates type 1 immune responses by controlling prompt infiltration of IL-12-producing granulocytes into sites of inflammation.
Mean levels in nonlinear analysis and identification (1993)

The effects of data pretreatment and mean levels upon nonlinear model structures is investigated. Techniques commmonly used to prefilter data in linear system identification are shown to alter the model structure in the nonlinear case. The effects of mean levels are considered in detail and a new unravelling algorithm is derived to recover the underlying system model when the offsets are external to the system. A new mapping from the time domain to the frequency domain is also introduced for the case where offsets can be considered as an implicit part of the system.
Mechanical Property Evaluation of Permanent-Mould Cast AM-SC1™ Mg-Alloy (2008)

&lt;div class="htmlview paragraph"&gt;AM-SC1&lt;sup&gt;™&lt;/sup&gt; is a high temperature Mg alloy that was originally developed as a sand casting alloy for automotive powertrain applications. The alloy has been selected as the engine block material for both the AVL Genios LE and the USCAR lightweight magnesium engine projects. The present work assesses the potential of this alloy for permanent-mould die cast applications. Thermo-physical and mechanical properties of AM-SC1 were determined for material derived from a permanent-mould die casting process. The mechanical properties determined included: tensile, creep, bolt load retention/relaxation and both low and high cycle fatigue. To better assess the creep performance, a comparative analysis of the normalized creep properties was carried out using the Mukherjee-Dorn parameter, which confirmed the high viscoplastic performance of AM-SC1 compared with common creep resistant high pressure die cast (HPDC) Mg-alloys.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;These investigations revealed excellent thermo-physical and mechanical properties that are, somewhat superior to the properties of the sand cast alloy, significantly superior to other HPDC magnesium alloys and comparable to pressure die cast aluminum alloy A380.&lt;/div&gt;
Planning Tools for Urban Sustainability (2014)

In this issue of Nordregio News, we explore new technologies and new tools for sustainable urban planning.
[Myocardial revascularization using bilateral internal mammary arteries for total occlusion of LMCA in an adult case: sequelae of Kawasaki's disease in childhood]. (1991)

A 43-year-old female patient suffering from effort angina underwent coronary artery bypass grafting. Coronary arteriogram demonstrated complete occlusion of the left main, proximal circumflex (Cx), and proximal left anterior descending coronary arteries (LAD) and a nonocclusive fusiform calcified aneurysm of the proximal right coronary artery (RCA). The left coronary artery system opacified via collateral vessels from the RCA. No other abnormalities were found in the entire aorta and its major branches. Myocardial revascularization was performed using the right IMA to bypass to the Cx and the left IMA to bypass to the LAD successfully. Prior to the operation, she had neither coronary risk factors nor inflammatory signs, though she had experienced fever of unknown origin lasting about a week when she was 11 years old. Accordingly we supposed that such coronary arterial lesions might have arisen from Kawasaki's disease in her childhood.
Discrete-time Gauss-Markov processes with fixed reciprocal dynamics (1997)

Motivated by a problem considered earlier by Schrodinger [1]--[2], Jamison [3]--[4] and others, we examine in this paper the construction of Gauss-Markov processes with fixed reciprocal dynamics. Given the class of reciprocal processes specified by a second-order model, a procedure is described for constructing a Markov process in the class with preassigned marginal probability densities at the end points. The problem of changing the final density of a Gauss-Markov process while remaining in the same reciprocal class is also examined, and is interpreted in terms of an estimation problem.
Genetic analysis of laminin A reveals diverse functions during morphogenesis in Drosophila (1993)

In order to dissect the functions of laminin A in vivo, we have undertaken a molecular and genetic characterization of the laminin A subunit (lamA) gene in Drosophila. Sequence analysis predicts a multidomain structure similar to mammalian homologs. We generated a series of complete and partial loss-of-function mutant alleles of the lamA gene; complete loss-of-function mutations lead to late embryonic lethality. Certain combinations of partial loss-of-function lamA alleles give rise to escaper adults, which have rough eyes associated with changes in cell fate and pattern, misshapen legs and defects in wing structure. These phenotypes suggest that laminin A has diverse functions during morphogenesis in Drosophila.
A visual preference-modeling and decision-support technique for buyers of multi-attribute products (2001)

We describe an intuitive, visual technique by which buyers of multi-attribute goods and services in electronic marketplaces can express their preferences, and receive real-time feedback about which transaction partners can most suitably meet their needs. Our work embodies a novel approach towards the visualization and conceptualization of multi-attribute spaces. Our system gives users the option of being able to iteratively refine their preferences based upon dynamically generated decision-support feedback.
Phase-Engineered Synthesis of Centimeter-Scale 1T′- and 2H-Molybdenum Ditelluride Thin Films (2015)

We report the synthesis of centimeter-scale, uniform 1T'- and 2H-MoTe2 thin films via the tellurization of Mo thin films. 1T'-MoTe2 was initially grown and converted gradually to 2H-MoTe2 over a prolonged growth time under a Te atmosphere. Maintaining excessive Te was essential for obtaining the stable stoichiometric 2H-MoTe2 phase. Further annealing under a lower partial pressure of Te at the same temperature, followed by a rapid quenching, led to the reverse phase transition from 2H-MoTe2 to 1T'-MoTe2. The orientation of the 2H-MoTe2 film was determined by the tellurization rate. Slow tellurization was the key for obtaining a highly oriented 2H-MoTe2 film over the entire area, while fast tellurization led to a 2H-MoTe2 film with a randomly oriented c-axis.
Heat-Shock Protein-70, -27 and Peroxiredoxin-2 Show Chaperone Function in Sickle Red Cells: Evidences from Transgenic Sickle Cell Mouse Model. (2007)

Abstract Sickle cell disease (SCD) is a worldwide-distributed hereditary red cell (RBCs) disorder characterized by the pathologic hemoglobin-S (HbS). The acute clinical manifestations of SCD are strictly related to HbS polymerization, to generation of dense RBCs, to their interaction with the abnormal activated vascular endothelial cells and to amplified inflammatory response. To identify new biomarkers associated with acute SCD events, we studied the RBCs membrane proteome from human SCD erythrocytes (n=20) fractioned according to density compared to normal RBCs (n=20), we divided RBCs into 2 fractions: fraction 1 (F1) corresponding to the least dense RBCs (density &lt; 1.074) and fraction 2 (F2) corresponding to the densest RBCs (density &gt; 1.095). None of the patients were under hydroxyurea treatment and they did not receive transfusion in the sixmonths before the study. Bi-dimensional electrophoresis (2-DE) followed by MS-analysis of RBCs F1 and F2 from both control and SCD subjects was carried out and 65 proteins differently expressed were identified. We focused on molecular chaperones. In SCD RBCs, we found that the amount of HSP27, HSP70 and Prx-2 recruited to the membrane was higher than in controls, Prx-2 was present as monomers and dimmers that were more abundant in SCD RBCs than in normal controls. Then, we exposed F1 and F2 fractions from normal and SCD patients to in vitro cellular stress (deoxygenation). In sickle RBCs, deoxygenation induced increase membrane recruitment of HSP27 in F1, modulation of HSP70 membrane binding in F2; reduction of Prx-2 monomers with increase Prx-2 dimerization in F1, but slightly changes in Prx-2 monomers in F2. These data suggest that in SCD RBCs HSP-27, -70 and Prx-2 are recruited to the membrane in response to cellular stress, acting as molecular chaperones to assist proteins in regaining their functional conformation. In order to evaluate their role in vivo and because increase serum levels of HSP70 has been recently reported in few SCD patients, we used transgenic sickle cell SAD mice as a model for SCD and exposed to hypoxia (8%-O2) respectively for 2–12–48 hours, mimicking acute human SCD vaso-occlusive-crisis (VOCs). We studies SAD mice and wild-type mice (C57/B6, WT) divided into groups of 6 animals each. We evaluated HSP70, HSP27 and Prx-2 expression on RBCs membrane, hematological parameters, RBCs density, and cation content. We found that HSP70 and HSP27 bound to RBCs membrane respectively after 12 hours and 48 hours (hrs) of hypoxia, while Prx-2 membrane binding was modulated during hypoxia. At the different time schedule, we observed a marked reduction in red cell K+ at 12 and 48 hrs hypoxia, associated with significant increase of the dense RBCs at 48 hrs hypoxia. Our data indicate that in SCD, HSP70, HSP27 and Prx-2 membrane recruitment is modulated in vivo during acute VOCs, supporting their novel role as RBCs membrane protein protectors and as new markers of severity of RBCs membrane damage during acute sickle VOCs.
On the Radiation Properties of Split-Ring Resonators (SRRs) at the Second Resonance (2015)

The radiation properties of split-ring resonators (SRRs) at their second resonance frequency are studied for the first time in this work. In particular, the electric and magnetic dipole moments of the edge-coupled SRR are calculated analytically under the assumption of strong coupling between the internal and external rings. Based on these results, the radiation resistance and the radiation efficiency are obtained theoretically. Electromagnetic simulations of the structure reveal that there is very good agreement with the theoretical predictions, pointing out the validity of the proposed analysis. As a proof of concept, an SRR antenna prototype is designed and fabricated. Experimental data are in good agreement with the theoretical and simulated results, and demonstrate the validity of the SRR working at its second resonance frequency as a radiating element.
ChemInform Abstract: Stereoselective Oxymercuration of Cyclopropylcarbinols with Anchimeric Assistance by Aromatic Groups. (2002)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A 70‐Year‐Old Mystery in Technetium Chemistry Explained by the New Technetium Polyoxometalate [H7O3]4[Tc20O68] ⋅ 4H2O (2021)

[H<sub>7</sub> O<sub>3</sub> ]<sub>4</sub> [Tc<sub>20</sub> O<sub>68</sub> ] ⋅ 4H<sub>2</sub> O [1] was prepared from an aqueous Tc<sub>2</sub> O<sub>7</sub> solution concentrated over anhydrous H<sub>2</sub> SO<sub>4</sub> . [Tc<sub>20</sub> O<sub>68</sub> ]<sup>4-</sup> is the first polyanionic species to be reported for Tc. The unit cell contains one centrosymmetric [Tc<sub>20</sub> O<sub>68</sub> ]<sup>4-</sup> polyanion as well as hydronium ions and water molecules. The core of the structure consists of four Tc(V)O<sub>6</sub> octahedra that form a square Tc<sub>4</sub> O<sub>4</sub> ring. The four Tc(V)O<sub>6</sub> octahedra are decorated by sixteen Tc(VII)O<sub>4</sub> tetrahedra. Calculations show the bonding within the Tc<sub>4</sub> O<sub>4</sub> ring to consist of a 3-center bond formed between each neighboring pair of Tc atoms and their bridging oxygen. Calculations also indicate that a strong d→d electronic transition at 513 nm is the origin of the red color of [1]. The characterization of red HTcO<sub>4</sub> solutions by X-ray absorption spectroscopy has complemented the description of this compound in aqueous solution. The formation mechanisms in solution, including the possible role of technetium's radioactivity in the formation of [1], are discussed.