gebhart/patrepeval huggingface dataset:
[Ultrasonic examination of soft tissue injuries in the shoulder region]. (1992)

Authors call attention with the demonstration of pictures of a few cases of their own to the significance of the ultrasound examination in cases of shoulder injuries. They stress that beside the demonstration of rotator cuff injuries the examination of the surrounding muscles and the labrum glenoidale should not be forgotten either. The modernization of the ultrasound devices, the improvement of the methods of examination and the obtaining of the necessary practice ensure a more and more important place to echography in the diagnosis of traumas of the motion organs.
Enhancement of lateral resolution and optical sectioning capability of two-photon fluorescence microscopy by combining temporal-focusing with structured illumination (2013)

We demonstrate super-resolution imaging with background fluorescence rejection by interferometric temporal focusing microscopy, in which temporal focusing is combined with structured illumination. The lateral resolution and the optical sectioning capability are simultaneously improved by factors of 1.6 and 1.4, respectively, compared to conventional temporal focusing microscopy. Fluorescent beads (200 nm diameter) that are difficult to distinguish from the background fluorescence in conventional temporal focusing microscopy, are clearly visualized by interferometric temporal focusing microscopy.
Biological removal of carbon and nitrogen compounds from coke plant wastes. [65 references] (1973)

A one-year study of a biological process for treatment of coke plant ammonia liquor was conducted. The process was designed to remove carbon compounds and ammonia. The pilot plant consisted of three treatment systems arranged in series. These systems were designed for the removal of carbon compounds, the oxidation of ammonia to nitrate (nitrification), and the reduction of nitrate to nitrogen gas (denitrification). The study was jointly sponsored by the American Iron and Steel Institute, the Environmental Protection Agency, and Armco Steel Corporation. The results indicate that the biological process can be used to remove carbon compounds and ammonia from dilute ammonia liquor. Treatment efficiencies obtained include removals of greater than 99.9 percent phenol, 80 percent COD and 90 percent ammonia. Removal efficiencies for cyanide and thiocyanate were less encouraging with averages of 57 and 17 percent, respectively. The inability to efficiently remove cyanide and thiocyanate raises a question as to the long range applicability of the process to existing and proposed water quality standards. A complete evaluation of the capabilities and limitations of the system was beyond the scope of this study. Additional development work would be required before the process could be considered for commercial application.
CARAVANA DA CIÊNCIA: A EXTENSÃO UNIVERSITÁRIA A SERVIÇO DO ENSINO INTERDISCIPLINAR DE CIÊNCIAS (2017)

Este trabalho apresenta uma metodologia interdisciplinar para a abordagem do processo ensino-aprendizagem ciências nas escolas de ensino médio. Motiva-se na observação da dificuldade corrente dos docentes em correlacionar o conteúdo programático com ciência - na ótica cotidiana. Sabendo-se das dificuldades relacionadas à infraestrutura das escolas, sobretudo da falta de laboratórios equipados, a metodologia perpassa técnicas de abordagens lúdicas, com materiais de baixo custo e principalmente na mudança de abordagem por parte do docente, de modo a potencializar os conhecimentos prévios dos alunos, os recursos existentes para melhor explicar fenômenos científicos e desse modo, compreender a relação deles de forma contextualizada. Como resultado, espera-se com o programa, que os docentes sejam capazes de revisitar as metodologias empregadas incorporando àquilo que julguem adicionador de valor, motivando o discente a correlacionar às disciplinas e a entender a importância da interdisciplinaridade no contexto singular de sua própria vida, afinal a ciência pode ser materializada em todas nossas percepções da realidade
A Mathematical Model for Vegetative Growth ofBacillus Thuringiensis (2001)

A structured but unsegregated model was developed for the vegetative growth of Bacillus thuringiensis (Bt) cells. This model included cell growth, limiting-substrate consumption, production and consumption of acetic acid, and production of poly-β-hydroxy butyric acid. The parameter estimation and model validation were conducted using data from carbon-limited batch experiments. The model successfully predicted batch behavior of biomass and glucose concentrations.
Effects of shrouded stator cavity flows on multistage axial compressor aerodynamic performance (1996)

Experiments were performed on a low-speed multistage axial-flow compressor to assess the effects of shrouded stator cavity flows on aerodynamic performance. Five configurations, which involved changes in seal-tooth leakage rates and/or elimination of the shrouded stator cavities, were tested. Data collected enabled differences in overall individual stage and the third stage blade element performance parameters to be compared. The results show conclusively that seal-tooth leakage ran have a large impact on compressor aerodynamic performance while the presence of the shrouded stator cavities alone seemed to have little influence. Overall performance data revealed that for every 1% increase in the seal-tooth clearance to blade-height ratio the pressure rise dropped up to 3% while efficiency was reduced by 1 to 1.5 points. These observed efficiency penalty slopes are comparable to those commonly reported for rotor and cantilevered stator tip clearance variations. Therefore, it appears that in order to correctly predict overall performance it is equally important to account for the effects of seal-tooth leakage as it is to include the influence of tip clearance flows. Third stage blade element performance data suggested that the performance degradation observed when leakage was increased was brought about in two distinct ways. First, increasing seal-tooth leakage directly spoiled the near hub performance of the stator row in which leakage occurred. Second, the altered stator exit now conditions caused by increased leakage impaired the performance of the next downstream stage by decreasing the work input of the downstream rotor and increasing total pressure loss of the downstream stator. These trends caused downstream stages to progressively perform worse. Other measurements were acquired to determine spatial and temporal flow field variations within the up-and-downstream shrouded stator cavities. Flow within the cavities involved low momentum fluid traveling primarily in the circumferential direction at about 40% of the hub wheel speed. Measurements indicated that the flow within both cavities was much more complex than first envisioned. A vortical flow structure in the meridional plane, similar to a driven cavity, existed within the upstream cavity Furthermore, other spatial and temporal variations in Row properties existed. the most prominent being caused by the upstream potential influence of the downstream blade. This influence caused the fluid within cavities near the leading edges of either stator blades in space or rotor blades in time to be driven radially inward relative to fluid near blade mid-pitch. This influence also produced large unsteady velocity fluctuations in the downstream cavity because of the passing of the downstream rotor blade.
Feature Selection for Mutlti-labeled Variables via Dependency Maximization (2019)

Feature selection and reducing the dimensionality of data is an essential step in data analysis. In this work we propose a new criterion for feature selection that is formulated as conditional information between features given the labeled variable. Instead of using the standard mutual information measure based on Kullback-Leibler divergence, we use our proposed criterion to filter out redundant features for the purpose of multiclass classification. This approach results in an efficient and fast non-parametric implementation of feature selection as it can be directly estimated using a geometric measure of dependency, the global Friedman-Rafsky (ΓR) multivariate run test statistic constructed by a global minimal spanning tree (MST). We demonstrate the advantages of our proposed feature selection approach through simulation. In addition the proposed feature selection method is applied to the MNIST data set.
Lipoprotein(a) Genetic Variants Associated With Coronary and Peripheral Vascular Disease but Not With Stroke Risk in the Heart Protection Study (2011)

The comparable strength of associations of the LPA score with coronary disease and peripheral vascular disease but not with stroke suggest that lipoprotein(a) may have effects on atherothrombotic vascular disease that are only relevant at specific sites. Clinical Trial Registration- URL: http://isrctn.org. Unique identifier: ISRCTN48489393.
Photoluminescence of erbium-implanted GaN and in situ-doped GaN:Er (1998)

The photoluminescence of in situ-doped GaN:Er during hydride vapor phase epitaxy was compared to an Er-implanted GaN sample. At 11 K, the main emission wavelength of the in situ-doped sample is shifted to shorter wavelengths by 2.5 nm and the lifetime is 2.1±0.1 ms as compared to 2.9±0.1 ms obtained for the implanted sample. The 295 K band edge luminescence of the in situ-doped sample was free of the broad band luminescence centered at 500 nm which dominated the spectrum of the implanted sample. Reversible changes in the emission intensity of the in situ-doped sample upon annealing in a N2 versus a NH3/H2 ambient indicate the probable role of hydrogen in determining the luminescence efficiency of these samples.
CADM1 Interacts with Tiam1 and Promotes Invasive Phenotype of Human T-cell Leukemia Virus Type I-transformed Cells and Adult T-cell Leukemia Cells (2010)

CADM1 encodes a multifunctional immunoglobulin-like cell adhesion molecule whose cytoplasmic domain contains a type II PSD95/Dlg/ZO-1 (PDZ)-binding motif (BM) for associating with other intracellular proteins. Although CADM1 lacks expression in T lymphocytes of healthy individuals, it is overexpressed in adult T-cell leukemia-lymphoma (ATL) cells. It has been suggested that the expression of CADM1 protein promotes infiltration of leukemic cells into various organs and tissues, which is one of the frequent clinical manifestations of ATL. Amino acid sequence alignment revealed that Tiam1 (T-lymphoma invasion and metastasis 1), a Rac-specific guanine nucleotide exchange factor, has a type II PDZ domain similar to those of membrane-associated guanylate kinase homologs (MAGUKs) that are known to bind to the PDZ-BM of CADM1. In this study, we demonstrated that the cytoplasmic domain of CADM1 directly interacted with the PDZ domain of Tiam1 and induced formation of lamellipodia through Rac activation in HTLV-I-transformed cell lines as well as ATL cell lines. Our results indicate that Tiam1 integrates signals from CADM1 to regulate the actin cytoskeleton through Rac activation, which may lead to tissue infiltration of leukemic cells in ATL patients.
Use of genetically modified muscle and fat grafts to repair defects in bone and cartilage (2009)

We report a novel technology for the rapid healing of large osseous and chondral defects, based upon the genetic modification of autologous skeletal muscle and fat grafts. These tissues were selected because they not only possess mesenchymal progenitor cells and scaffolding properties, but also can be biopsied, genetically modified and returned to the patient in a single operative session. First generation adenovirus vector carrying cDNA encoding human bone morphogenetic protein-2 (Ad.BMP-2) was used for gene transfer to biopsies of muscle and fat. To assess bone healing, the genetically modified (“gene activated”) tissues were implanted into 5mm-long critical size, mid-diaphyseal, stabilized defects in the femora of Fischer rats. Unlike control defects, those receiving gene-activated muscle underwent rapid healing, with evidence of radiologic bridging as early as 10 days after implantation and restoration of full mechanical strength by 8 weeks. Histologic analysis suggests that the grafts rapidly differentiated into cartilage, followed by efficient endochondral ossification. Fluorescence in situ hybridization detection of Y-chromosomes following the transfer of male donor muscle into female rats demonstrated that at least some of the osteoblasts of the healed bone were derived from donor muscle. Gene activated fat also healed critical sized defects, but less quickly than muscle and with more variability. Anti-adenovirus antibodies were not detected. Pilot studies in a rabbit osteochondral defect model demonstrated the promise of this technology for healing cartilage defects. Further development of these methods should provide ways to heal bone and cartilage more expeditiously, and at lower cost, than is presently possible.
Photoacoustic characterization of n-RuSe2 semiconductor pellets (2000)

Using the open photoacoustic cell technique, a set of physical properties for a semiconductor (n-RuSe2) in powder form was measured. According to the Dramicanin theoretical model, charge carriers transport parameters (bulk and surface) and the effective thermal diffusivity were obtained.
Cannabis, More Than the Euphoria: Its Therapeutic Use in Drug-Resistant Epilepsy (2020)

A significant number of epilepsy patients are refractory to conventional antiepileptic drugs. These patients experience considerable neurocognitive impairments that impact their quality of life and ability to function independently. This need for alternative treatment has generated increased interest in cannabis use as a therapeutic option in these patients. This review seeks to analyze data presented on the pharmacology, safety, and efficacy of cannabis use in patients with drug-resistant epilepsy (DRE) and to propose any future recommendations regarding its use. PubMed was used to retrieve all published studies and articles which evaluated the use of cannabis in epilepsy. The two foremost phytocannabinoids of cannabis showing anticonvulsant properties are tetrahydrocannabinol (THC) and cannabidiol (CBD). Due to the psychoactive properties of THC, most studies focused on CBD use in these patients. The use of CBD as an adjunct resulted in decreased seizure frequency, and secondary benefits observed included improvement in mood, alertness and sleep. Adverse events (AEs) reported were drowsiness, diarrhea, increased transaminases and worsening of seizures. It can safely be concluded that there is a significant benefit in DRE patients using CBD as adjunctive therapy. However, further controlled and adequately powered studies are needed to assess the pharmacokinetics and impact of the long-term use of cannabis.
Upper Bounds for Covering Designs by Simulated Annealing (1993)

A t \\Gamma (v; m; k; ) covering design is a pair (X; A), where X is a set of v elements (called points) and A is a multiset of k-subsets of X (called blocks), such that every m-subset of X intersects at least members of A in at least t points. It is required that v k t and v m t. Such a covering design gives an upper bound on C (v; m; k; t), the number of blocks in a minimal t \\Gamma (v; m; k; ) covering design. In this paper it is shown how simulated annealing, a probabilistic method for solving combinatorial optimization problems, can be used to construct covering designs. Implementation of this method is discussed. The method is used to calculate new upper bounds on C 1 (v; t; k; t) for k 9, v 13. A new exact value, C 1 (11; 4; 6; 4) = 32, is obtained.
Excitation by Vortices Shedding Periodically from Two Cylinders in Cruciform Arrangement. (1992)

The behavior of the excitation caused by longitudinal vortices shedding from two cruciform circular cylinders with an equal diameter d is investigated using a wind tunnel. When the gap s between two cylinders is less than d/2, longitudinal vortices shed periodically and a fluctuating lift force is exerted on the upstream cylinder. The nondimensional frequency, StM, of the longitudinal vortices is independent of the Reynolds number. The value of StM is 0.06<StM<0.09 when s/d<0.25 (region A) and StM≒0.04 when 0.25<s/d<0.5 (region B). The fluctuating lift force on the upstream cylinder is estimated from the pressure on the cylinder surface using a phase-averaging technique. The result shows that the flow near the crossing of the cylinder is dominated by four trailing vortices in the region A and by two necklace vortices in the region B. These vortices shed an anti-phase on the opposite side of the upstream cylinder, causing an alternative lift force to be exerted on it. The abrupt change of StM at s/d=0.25 is caused by the fact that these two types of vortices interchange their role to excite the upstream cylinder.
Large size citrate‐reduced gold colloids appear as optimal SERS substrates for cationic peptides (2016)

Surface‐enhanced Raman spectra of two cyclic cationic peptides with therapeutic interest, somatostatin‐14 and its synthetic analog octreotide, were simultaneously analyzed as a function of concentration and colloidal size. It appeared that the large size (~95 nm) citrate‐reduced gold nanoparticles are the most adequate substrates for providing an optimal Raman signal enhancement within the 10 −6 –10 −7 m peptide concentration range. It could also be evidenced that these large size particles can give rise to such a remarkable result within the first month following their elaboration. In fact, the recorded Raman spectra after this period mainly originate from the molecular species in the coverage of gold particles and not from the adsorbed peptides. To bring clarification to the temporal evolution of gold colloids, a systematic analysis was performed during 3 months on different particle sizes in the 15–150 nm range. The data obtained by a combined use of different techniques (Ultraviolet‐visible absorption, z‐potential, transmission electron microscopy, and Raman scattering) are consistent with a permanent evolution of the colloidal coverage, assignable to the gradual transformation of citrate anions and their substitution by oxidized products. It can be concluded that only small and medium size nanoparticles (≤ 40 nm) are able to regenerate their initial features after the first month, while large size colloids are subjected to a continuous degradation of their plasmonic and electrostatic properties. Copyright © 2016 John Wiley &amp; Sons, Ltd.
Attenuated Total Internal Reflection Fourier Transform Infrared Spectroscopy: A Quantitative Approach for Kidney Stone Analysis (2009)

The impact of kidney stone disease is significant worldwide, yet methods for quantifying stone components remain limited. A new approach requiring minimal sample preparation for the quantitative analysis of kidney stone components has been investigated utilizing attenuated total internal reflection Fourier transform infrared spectroscopy (ATR-FT-IR). Calcium oxalate monohydrate (COM) and hydroxylapatite (HAP), two of the most common constituents of urinary stones, were used for quantitative analysis. Calibration curves were constructed using integrated band intensities of four infrared absorptions versus concentration (weight %). The correlation coefficients of the calibration curves range from 0.997 to 0.93. The limits of detection range from 0.07 +/- 0.02% COM/HAP where COM is the analyte and HAP is the matrix, to 0.26 +/- 0.07% HAP/COM where HAP is the analyte and COM is the matrix. This study shows that linear calibration curves can be generated for the quantitative analysis of stone mixtures provided the system is well understood especially with respect to particle size.
An automatic experimental set-up for robustness analysis of designs implemented on SRAM FPGAS (2011)

This paper introduces an experimental test-flow for evaluating the susceptibility of SRAM based FPGA designs to SEU (Single Event Upsets). Using this method it is possible to cover both SEUs and MBU (Multiple Bit Upsets) in the configuration memory of Xilinx FPGAs for applications based on tiny soft microprocessors. The introduced test-flow imposes a minimal effort to the system developer and achieves a good estimation on the percentage of critical bits in the configuration memory of a design. This flow is executed for a design using multiple tiny soft microprocessors and the reliability values extracted by the test-flow are compared to non-experimental estimation techniques.
Postoperative Immunosuppression After Open and Laparoscopic Liver Resection: Assessment of Cellular Immune Function and Monocytic HLA-DR Expression (2013)

Major immunoparalysis depression was not observed in either group. Laparoscopic surgery shows a tendency to improve immunologic recovery after liver resection.
Faculty Opinions recommendation of Membrane Tension Gates ERK-Mediated Regulation of Pluripotent Cell Fate. (2020)

Cell fate transitions are frequently accompanied by changes in cell shape and mechanics. However, how cellular mechanics affects the instructive signaling pathways controlling cell fate is poorly understood. To probe the interplay between shape, mechanics, and fate, we use mouse embryonic stem cells (ESCs), which change shape as they undergo early differentiation. We find that shape change is regulated by a β-catenin-mediated decrease in RhoA activity and subsequent decrease in the plasma membrane tension. Strikingly, preventing a decrease in membrane tension results in early differentiation defects in ESCs and gastruloids. Decreased membrane tension facilitates the endocytosis of FGF signaling components, which activate ERK signaling and direct the exit from the ESC state. Increasing Rab5a-facilitated endocytosis rescues defective early differentiation. Thus, we show that a mechanically triggered increase in endocytosis regulates early differentiation. Our findings are of fundamental importance for understanding how cell mechanics regulates biochemical signaling and therefore cell fate.Copyright © 2020 The Author(s). Published by Elsevier Inc. All rights reserved. PMID: 33217323 Funding information This work was supported by: Wellcome Trust, United Kingdom Grant ID: 203151/Z/16/Z Medical Research Council, United Kingdom Grant ID: MC_PC_12009 Wellcome Trust, United Kingdom Medical Research Council, United Kingdom Grant ID: MC_UU_12018/5 Medical Research Council, United Kingdom Grant ID: MC_UU_00012/5 Medical Research Council, United Kingdom Grant ID: MC_PC_17230 More Less keyboard_arrow_down
Slippage of DNA polymerase I during synthesls of ds-cDNA (1988)

Journal Article Slippage of DNA polymerase I during synthesls of ds-cDNA Get access R. Devos, R. Devos BIOGENT, J. Plateaustraat 22, 9000 Gent and Laboratorium voor Moleculaire Biologie, Rijksuniversiteit Gent, Ledeganckstraat 35, 9000 Gent, Belgium Search for other works by this author on: Oxford Academic PubMed Google Scholar J. Tavernier, J. Tavernier BIOGENT, J. Plateaustraat 22, 9000 Gent and Laboratorium voor Moleculaire Biologie, Rijksuniversiteit Gent, Ledeganckstraat 35, 9000 Gent, Belgium Search for other works by this author on: Oxford Academic PubMed Google Scholar W. Fiers W. Fiers BIOGENT, J. Plateaustraat 22, 9000 Gent and Laboratorium voor Moleculaire Biologie, Rijksuniversiteit Gent, Ledeganckstraat 35, 9000 Gent, Belgium Search for other works by this author on: Oxford Academic PubMed Google Scholar Nucleic Acids Research, Volume 16, Issue 4, 25 February 1988, Page 1630, https://doi.org/10.1093/nar/16.4.1630 Published: 25 February 1988 Article history Accepted: 23 December 1987 Published: 25 February 1988