gebhart/patrepeval huggingface dataset:
Active Contact Physiotherapy System (2021)

It is easy for human body to contact with objects for a long time to cause fatigue of corresponding parts. How to use robot technology to reduce or eliminate this fatigue in order to improve work efficiency, ensure human health and improve comfort is an important problem in the field of robot. In this paper, combined with the characteristics of animal tissues (puffer’s air bag, etc.), through the application of soft robot related technology, a set of program-controlled active flexible massage system is made. The system is mainly composed of support frame, air bag placement module and electrical system. The system can be freely deformed and combined, soft and comfortable, and has strong expansibility. In addition, we propose a control method to calculate the relationship between the air pressure inside the airbag and the surface tension of the airbag, set four working modes for the system, and measure the air pressure inside the airbag under the four modes. The results show that the proposed control method is feasible and will have a very broad application prospect in medical rehabilitation.
Angiosarcoma of the breast, the unknown—a review of the current literature (2019)

Angiosarcoma of the breast is one of the rarest malignancies. Breast angiosarcoma can be classified into primary when arising de novo and secondary to chronic lymphoedema or breast irradiation. Molecular pathways involved in angiosarcoma development have not been described clearly, yet some gene point mutations and protein altered expression levels have been detected. So far, their management is based above all on surgery. Hence, further studies starting from the few known key points may help to develop more effective strategies based both on target therapies, together with surgery.
A subclass of dendritic cells regulates the response of naive CD8 T cells by limiting their IL-2 production (1996)

Previous work indicated that a subclass of mouse spleen dendritic cells (DC), those bearing CD8alpha, expresses the Fas ligand and restricts peripheral CD4 T cell responses by initiating Fas-mediated apoptosis. To determine whether a similar regulation applies to CD8 T cells, they were purified from normal or from TCR-transgenic mice, and then cultured with purified splenic CD8+ DC or CD8- DC presenting either alloantigens or the specific Ag for the TCR transgene. In all systems studied, the proliferative response of CD8 T cells was markedly less on stimulation with CD8+ DC compared with conventional CD8- DC. However, the basis of this restricted proliferation in response to CD8+ DC was totally different for CD8 T cells than for CD4 T cells. The reduced proliferation of CD8 T cells occurred later in the response than with CD4 T cells. In contrast with CD4 T cells, the reduced proliferation of CD8 T cells occurred even with T cells from Fas-deficient Ipr mice, or with DC from Fas ligand-deficient gld mice, indicating that Fas-induced apoptosis was not involved. Also, in contrast with CD4 T cells, the reduced proliferation of CD8 T cells was completely reversed by the addition of exogenous IL-2. Furthermore, cultures of CD8 T cells with CD8+ DC were found to be deficient in IL-2 production. Accordingly, although CD8+ DC are very efficient at stimulating CD8 T cells into cell division, they are deficient at stimulating endogenous cytokine production. The implications of these different DC regulatory systems are discussed.
Machine Learning for Wireless Networks (2022)

A summary is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
De Novo Pathogenic Variants in CACNA1E Cause Developmental and Epileptic Encephalopathy with Contractures, Macrocephaly, and Dyskinesias (vol 103, pg 666, 2018) (2019)

(The American Journal of Human Genetics 103, 666–678; November 1, 2018) In the version of this article originally published online, Qinghe Xing's name was misspelled as Qinghe Xin. Also, Azita Sadeghpour, Erica E. Davis, and Nicholas Katsanis (all at Center for Human Disease Modeling, Duke University Medical Center, Durham, NC 27701, USA) and the Task Force for Neonatal Genomics were omitted from the author list. The members of the Task Force for Neonatal Genomics are as follows: Alexander Allori, Misha Angrist, Patricia Ashley, Margarita Bidegain, Brita Boyd, Eileen Chambers, Heidi Cope, C. Michael Cotten, Theresa Curington, Erica E. Davis, Sarah Ellestad, Kimberley Fisher, Amanda French, William Gallentine, Ronald Goldberg, Kevin Hill, Sujay Kansagra, Nicholas Katsanis, Sara Katsanis, Joanne Kurtzberg, Jeffrey Marcus, Marie McDonald, Mohammed Mikati, Stephen Miller, Amy Murtha, Yezmin Perilla, Carolyn Pizoli, Todd Purves, Sherry Ross, Azita Sadeghpour, Edward Smith, and John Wiener. The authors apologize for these omissions.
An Automated Method for Chemical Composition Analysis of Lubricant Base Oils by Using Atmospheric Pressure Chemical Ionization Mass Spectrometry (2019)

Since its invention in the 1950s, field ionization mass spectrometry (FI MS) has been, and currently is, the go-to technique employed by the petrochemical industry for the identification of the different types of nonvolatile compounds in their products. Unfortunately, FI MS has several inherent drawbacks, such as poor reproducibility. The performance of positive-ion mode atmospheric pressure chemical ionization mass spectrometry (APCI MS) with O<sub>2</sub> gas as the sheath/auxiliary gas and a saturated hydrocarbon solvent/reagent was recently compared with that of FI MS and found to show promise as an alternative, highly reproducible method for lubricant base oil analysis. We report here on the automation of the APCI/O<sub>2</sub>/saturated hydrocarbon MS method. Isooctane was chosen as the optimal APCI solvent/reagent for base oil ionization due to the low level of fragmentation it provided for model compound mixtures. Three minutes was determined to be the shortest possible cleaning time between samples, regardless of the base oil viscosity. The total analysis time for each sample was 5 min. The reproducibility of the method was assessed by determining within-day and between-day precisions and total precision for hydrocarbon class distributions measured for three different base oils. All total precision values were found to be better than 6.2%, suggesting that the automated (+)APCI/O<sub>2</sub>/isooctane method is reproducible and robust.
Issues in implementing latency insensitive protocols (2004)

A design that works under the assumption of zero-delay connections between functional modules is modified in a latency insensitive design (LID) by encapsulating them within the wrappers ("shells") and connecting them through internally pipelined blocks ("relay stations") complying with a protocol that guarantees identity of behavior.
The guinea pig as a model for the asymptomatic human typhoid carrier. (1977)

Studies were designed to develop an animal model which mimics the asymptomatic carrier state of typhoid fever, Salmonella typhi infection, in man. The gallbladder of the guinea pig [Can (HA)] was surgically cannulated to provide a route for infection and bile sampling. Organisms (2 X 10(8) S typh:) were introduced by way of the cannula and samples of bile removed and analyzed periodically. Salmonella typhi was recovered from the bile and feces of infected, yet apparently normal, guinea pigs for periods of up to 5 months thus mimicking the human symptomeles carrier. Some guinea pigs were treated with chloramphenicol after infection. Antibiotic therapy with chloramphenicol did not eliminate the carrier state. Microabscesses of the liver were induced by S typhi both in untreated and treated animals (cultures were positive from these abscesses). When blood antibiotic levels dropped, the organism was found in the bile fluid and was again excreted. Vaccinated guinea pigs developed elevated levels of 0 and H serum antibody, but were not protected against infection of the gallbladder with S typhi (2 X 10(8) organisms). Similarly, vaccination failed to eliminate the carrier state.
Effects of Delayed-Release Olive Oil and Hydrolyzed Pine Nut Oil on Glucose Tolerance, Incretin Secretion and Appetite in Humans (2021)

In support of previous findings, 6 g of delayed-release hydrolyzed pine nut oil enhanced postprandial GLP-1 secretion and reduced appetite. However, no synergistic effect of combining hydrolyzed pine nut oil and olive oil on GLP-1 secretion was observed. These results need further evaluation in long-term studies including effects on bodyweight and insulin sensitivity.
How does social anger expression predict later depression symptoms? It depends on how often one is angry. (2016)

Research has suggested that there are benefits to socially sharing anger as an emotion regulation strategy. We hypothesized that these benefits may depend on the frequency with which one is experiencing anger. We used an experience sampling methodology to explore the interaction between frequency of anger and reliance on social expression of anger as a predictor of changes in depression symptoms 4 months later. We found that a strong reliance on social expression prospectively predicted lower depression symptoms when participants endorsed anger infrequently but predicted an increase in subsequent depression symptoms when anger was endorsed frequently. This interaction was specific to anger and did not extend to sadness or anxiety. These results highlight the importance of considering the effectiveness of emotion regulation strategies in the context of specific emotions and the frequency of the experienced emotion in everyday life. (PsycINFO Database Record
Re‐annotation, improved large‐scale assembly and establishment of a catalogue of noncoding loci for the genome of the model brown alga Ectocarpus (2016)

The genome of the filamentous brown alga Ectocarpus was the first to be completely sequenced from within the brown algal group and has served as a key reference genome both for this lineage and for the stramenopiles. We present a complete structural and functional reannotation of the Ectocarpus genome. The large-scale assembly of the Ectocarpus genome was significantly improved and genome-wide gene re-annotation using extensive RNA-seq data improved the structure of 11 108 existing protein-coding genes and added 2030 new loci. A genome-wide analysis of splicing isoforms identified an average of 1.6 transcripts per locus. A large number of previously undescribed noncoding genes were identified and annotated, including 717 loci that produce long noncoding RNAs. Conservation of lncRNAs between Ectocarpus and another brown alga, the kelp Saccharina japonica, suggests that at least a proportion of these loci serve a function. Finally, a large collection of single nucleotide polymorphism-based markers was developed for genetic analyses. These resources are available through an updated and improved genome database. This study significantly improves the utility of the Ectocarpus genome as a high-quality reference for the study of many important aspects of brown algal biology and as a reference for genomic analyses across the stramenopiles.
The onset of dissipation in high-temperature superconductors: magnetic hysteresis and field dependence (2020)

© 2018, The Author(s). Recently, we showed that the self-field transport critical current, Ic(sf), of a superconducting wire can be defined in a more fundamental way than the conventional (and arbitrary) electric field criterion, Ec = 1 μV/cm. We defined Ic(sf) as the threshold current, Ic,B, at which the perpendicular component of the local magnetic flux density, B⊥, measured at any point on the surface of a high-temperature superconducting tape abruptly crosses over from a non-linear to a linear dependence with increasing transport current. This effect results from the current distribution across the tape width progressively transitioning from non-uniform to uniform. The completion of this progressive transition was found to be singular. It coincides with the first discernible onset of dissipation and immediately precedes the formation of a measureable electric field. Here, we show that the same Ic,B definition of critical currents applies in the presence of an external applied magnetic field, Ba. In all experimental data presented here Ic,B is found to be significantly (10–30%) lower than Ic,E determined by the common electric field criterion of Ec = 1 µV/cm, and Ec to be up to 50 times lower at Ic,B than at Ic,E.
Reduced threshold microdisk lasers from GeSn/SiGeSn heterostructures (2017)

We present optically pumped lasing from group IV GeSn/SiGeSn heterostructures. A comparison between double heterostructure and multi-quantum-well microdisk cavities reveals advantages of the multi-well design. Strongly reduced lasing thresholds compared to values from bulk devices are observed.
Novel mechanism of resistance to targeted therapies in lung cancer (2018)

We have identified a non-canonical role of0 Notch3 in response to epidermal growth factor receptor (<i>EGFR</i>) tyrosine kinase inhibitor (TKI) therapy, whereby Notch3 associates with β-catenin, resulting in increased catenin beta-1 (CTNNB1, best known as β-catenin) stability and increased survival of drug persister cells (DPCs). Furthermore, combined treatment of an EGFR TKI with a β-catenin inhibitor demonstrated improved therapeutic outcomes in xenograft models.
Biochemical Activities of Extracts from Hypericum perforatum L. 1st Communication: Inhibition of dopamine - β - hydroxylase (2011)

Extracts from the herb "St. John's wort" (Hypericum perforatum L.) are used for the treatment of mental depression, nervousness, sleeplessness and for their wound healing, diuretic and antirheumatic properties. As one biochemical mechanism for depression lack of catecholamine neurotransmitters has been discussed. The results of this investigation show that alcoholic extracts from Hypericum perforatum L. on the basis of total hypericin content inhibit dopamine-beta-hydroxylase with an IC50 of 0.1 mu mol/l; pure commercial hypericin inhibits with an IC50 of 21 mu mol/l. Enzymes involved in the synthesis of dopamine from tyrosine, namely tyrosinase and tyrosine decarboxylase, are not influenced by hypericin at concentrations from 1 up to 10 mu mol/l.
Electrodeless photo-assisted electrochemical etching of GaN using a H3PO4-based solution containing S2O8 2– ions (2019)

Electrodeless PEC etching was successfully demonstrated using a H3PO4-based solution containing S2O8 2-ions. The pH value of the solution changed under UVC illumination, clearly showing that SO4 -radicals were produced from S2O8 2-ions by absorbing UVC light. The production rate of SO4 -radicals kept a constant value in the wide pH range of the solution, leading to etching rates and surface roughness comparable with those obtained in KOH-based solutions. The positive-type photoresist was applicable as the etching mask for the H3PO4-based solution. This finding will contribute to a simple wet etching process suitable for the manufacturing of GaN-based devices.
Characterization of ZnS Nanoparticle Aggregation using Photoluminescence (2011)

Aggregation of uncoated ZnS nanoparticles was determined to have an unexpected impact on the particle's photoluminescent properties. Aggregation had significant consequences to both band-edge and trap-site photoluminescence, increasing the former and decreasing the latter. The onset of changes to photoluminescence was influenced by aggregation rate. Results suggest that aggregate structure plays an important role in determining the extent to which changes to photoluminescence occur. Strong evidence is presented in support of the hypothesis that aggregation-induced changes to surface tension are responsible for the observed photoluminescence behavior. We show that changes in photoluminescence can be used to predict the attachment coefficient, in lieu of dynamic light scattering. Additionally, our data indicate that the particle size distribution of aggregating ZnS nanoparticles is invariant across electrolyte concentrations, at a given standard deviation away from the maximum rate of photoluminescence change.
Shortest path computations under trajectory constraints for ground vehicles within agricultural fields (2016)

This paper addresses the task of finding the shortest path to a target point on the boundary of an agricultural working area given a current position and heading of a ground vehicle within that area. Constraints such as admittance of turning on the spot, lane- and corridor-constraining motion as well as repressed area minimization are taken into account. We distinguish between orchard- and vineyard-like areas and agricultural fields growing, in particular, rapeseed and cereals. For the former application, dynamic programming and label-correcting algorithms are compared and, based on a coordinate transformation, a heuristic is motivated therefore. For the latter agricultural field application, we constrain the shortest path objective by allowing agricultural machinery to only use already existing tractor-lane traces and thus introduce a repressed area minimization constraint. Therefore, a customized and novel shortest path finding method is derived, before its optimality is proven. The outcome of this work is equally applicable for autonomous as well as manually driven agricultural ground vehicles.
Astrocyte gene expression in Creutzfeldt-Jakob disease. (1987)

Gliosis (hyperplasia and hypertrophy of astrocytes), the fundamental response of the central nervous system to tissue destruction, typically becomes apparent only several weeks after injury. The biochemical hallmark of this response is a marked accumulation of the specific astrocyte intermediate filament glial fibrillary acidic protein (GFAP). To date despite its importance, the mechanisms of GFAP gene regulation have not been studied in any developmental or pathological system to our knowledge, and the molecular signals for GFAP mRNA and protein accumulation are not defined. In Creutzfeldt-Jakob disease, a progressive dementing illness caused by an "unconventional agent," we find steadily increasing elevations of GFAP mRNA throughout the later stages of disease, using two independent GFAP cDNA clones, representing the entire insert or the 3'-noncoding region (pScr-1). The accumulation of GFAP, assessed immunocytochemically, follows GFAP mRNA elevation. A 5-fold stimulation of GFAP gene expression precedes the development of florid histologic lesions in the cerebrum, and in the cerebellum 5- to 6-fold increases occurred with no detectable spongiform changes at any time during disease. Therefore, these GFAP changes cannot be simply a response to neuronal damage. These effects are directly or indirectly caused by high local concentrations of agent and possibly involve a humoral factor.
Versatile Eco‐friendly Pickering Emulsions Based on Substrate/Native Cyclodextrin Complexes: A Winning Approach for Solvent‐Free Oxidations (2013)

Abstract Solvent‐less Pickering emulsions were developed and applied to catalytic oxidation. These systems are stabilized by inclusion complexes between cyclodextrins and substrates, forming a 3D network among the dispersed phase. In the presence of hydrogen peroxide as a green oxidant and [Na] 3 [PW 12 O 40 ] as a catalyst, they provide particularly efficient reaction media for the oxidation of olefins, organosulfurs, and alcohols. The reactions proceed at competitive rates (up to 400 h −1 ) with straightforward separation of the phases by centrifugation or heating. Moreover, these new eco‐friendly systems work at a preparative scale (up to 2.5 M ) and are recycled without loss of activity.
Akinetic crisis, acute akinesia, neuroleptic malignant‐like syndrome, Parkinsonism–hyperpyrexia syndrome, and malignant syndrome are the same entity and are often independent of treatment withdrawal (2005)

Abstract A reply to this letter has been published in Movement Disorders Mov Disord (2005)DOI 10.1002/mds.20688 .
Object localization using deformable templates (2008)

Object localization refers to the detection, matching and segmentation of objects in&#13;\nimages. The localization model presented in this paper relies on deformable templates&#13;\nto match objects based on shape alone. The shape structure is captured by a prototype&#13;\ntemplate consisting of hand-drawn edges and contours representing the object to be&#13;\nlocalized. A multistage, multiresolution algorithm is utilized to reduce the computational&#13;\nintensity of the search. The first stage reduces the physical search space dimensions&#13;\nusing correlation to determine the regions of interest where a match it likely to occur.&#13;\nThe second stage finds approximate matches between the template and target image at&#13;\nprogressively finer resolutions, by attracting the template to salient image features using&#13;\nEdge Potential Fields. The third stage entails the use of evolutionary optimization to&#13;\ndetermine control point placement for a Local Weighted Mean warp, which deforms the&#13;\ntemplate to fit the object boundaries. Results are presented for a number of applications,&#13;\nshowing the successful localization of various objects. The algorithm’s invariance to&#13;\nrotation, scale, translation and moderate shape variation of the target objects is clearly&#13;\nillustrated.
Resolution of Pd Catalyst with tropos Biphenylphosphine (BIPHEP) Ligand by DM-DABN:  Asymmetric Catalysis by an Enantiopure BIPHEP−Pd Complex1 (2001)

[reaction: see text] The racemic Pd complex with the chirally flexible (tropos) biphenylphosphine (BIPHEP) ligand can be resolved with enantiopure 3,3'-dimethyl-2,2'-diamino-1,1'-binaphthyl (DM-DABN) as a resolving agent at room temperature. The enantiopure BIPHEP-Pd complex is obtained from complexation with enantiopure DABN followed by tropo-inversion into the single BIPHEP-Pd diastereomer at 80 degrees C and protonation at 0 degrees C. The enantiopure BIPHEP-Pd complex can be used as an efficient Lewis acid catalyst for the Diels-Alder reaction at room temperature to give high enantioselectivity (82% ee, 60%).
The complex backpropagation algorithm (1991)

The backpropagation (BP) algorithm that provides a popular method for the design of a multilayer neural network to include complex coefficients and complex signals so that it can be applied to general radar signal processing and communications problems. It is shown that the network can classify complex signals. The generalization of the BP to deal with complex signals should make it possible to expand the line of applications of this powerful nonlinear signal processing algorithm.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Über die Natur der Übergangsmetall‐Kohlenstoff‐σ‐Bindung. I. σ‐Organyl‐eisen(II)‐phthalocyanine (1977)

Abstract Es werden die Bildung von σ‐Organyl‐eisen(II)‐phthalocyaninen durch Umsetzung von Eisen(0)‐phthalocyanin, Li 2 [Fe 0 Pc] · 5,5 THF, mit Organylhalogeniden und durch Carbanionen‐Addition an Eisen(II)‐ und Eisen(III)‐phthalocyanin untersucht und die Darstellung und Eigenschaften der Komplexe Li[RFePc]·x THF (R = CH 3 , C 6 H 5 , CH 2 CHC 6 H 5 , COC 6 H 5 ), Li[Br(CH 2 ) 4 FePc] · LiBr · 8 THF, Li 2 [PcFe(CH 2 ) 4 FePc] · 10 THF, Li[C 6 H 5 C 2 FePc(Py)] · 4 THF, Li 2 [(C 6 H 5 C 2 ) 2 FePc] · 7 THF und [FePc(THF) 2 ] beschrieben.