gebhart/patrepeval huggingface dataset:
Localization Prediction in Vehicular Ad Hoc Networks (2018)

Localization systems play a major role in many applications for vehicular ad hoc networks (VANETs). One of the most interesting problems to be solved in vehicular networks is how to provide anywhere and anytime highly accurate and reliable localization information. Unique characteristics of VANETs such as mobility constraints, driver's behavior, and the highspeed displacement nature of vehicles cause rapid and constant changes in network topology, leading to dissemination of outdated localization information. To circumvent this problem, an alternative is the use of predicted future locations of vehicles. The main idea of this approach is to use the localization prediction as an extension of a data fusion localization system. In such an approach, a future position of a vehicle is predicted for a given future time and used to take advantage of a future time-space window of a vectorial trajectory rather than a static localization point. In this paper, we discuss this subject by studying and analyzing the use of localization prediction as natural way to improve VANET applications. We survey proposed approaches for localization, target tracking, and time series prediction techniques that can be used to estimate the future position of a vehicle. We also highlight their advantages and disadvantages through an analytical discussion visualizing its potential application scenarios in VANETs. We present a set of experiments that show the results of such techniques when applied to a realistic VANET scenario <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sup> .
Objectness to improve the bag of visual words model (2014)

The objectness measure identifies the image region that potentially contains any kind of object. This work studies several ways of using the objectness measure to improve the bag of visual words model for object recognition. The first approach is to extract descriptors only from the image regions with a high objectness score in order to obtain the vocabulary of visual words. The second approach is to weight the visual words from a standard vocabulary, according to the objectness measure computed on each image. The two approaches are also combined together using multiple kernel learning. Object recognition experiments are conducted to assess the performance level gained by integrating the objectness measure in the bag of visual words model. The empirical results show that the objectness measure can indeed improve the performance, by demoting the visual words located on the background of the image.
Variable-temperature single-crystal electron spin resonance study and crystal structure of bis(1,4,7-triazacyclononane)copper(2+) tricyanocuprate(2-) dihydrate at 110 and 293 K. Static and dynamic Jahn-Teller distortions in the CuN6 polyhedron (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTVariable-temperature single-crystal electron spin resonance study and crystal structure of bis(1,4,7-triazacyclononane)copper(2+) tricyanocuprate(2-) dihydrate at 110 and 293 K. Static and dynamic Jahn-Teller distortions in the CuN6 polyhedronPhalguni Chaudhuri, Karen Oder, Karl Wieghardt, Johannes Weiss, Jan Reedijk, Winfried Hinrichs, John Wood, Andrej Ozarowski, Horst Stratemaier, and Dirk ReinenCite this: Inorg. Chem. 1986, 25, 17, 2951–2958Publication Date (Print):August 1, 1986Publication History Published online1 May 2002Published inissue 1 August 1986https://pubs.acs.org/doi/10.1021/ic00237a007https://doi.org/10.1021/ic00237a007research-articleACS PublicationsRequest reuse permissionsArticle Views185Altmetric-Citations49LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Digital Twin-Driven Human Robot Collaboration Using a Digital Human (2021)

Advances are being made in applying digital twin (DT) and human-robot collaboration (HRC) to industrial fields for safe, effective, and flexible manufacturing. Using a DT for human modeling and simulation enables ergonomic assessment during working. In this study, a DT-driven HRC system was developed that measures the motions of a worker and simulates the working progress and physical load based on digital human (DH) technology. The proposed system contains virtual robot, DH, and production management modules that are integrated seamlessly via wireless communication. The virtual robot module contains the robot operating system and enables real-time control of the robot based on simulations in a virtual environment. The DH module measures and simulates the worker's motion, behavior, and physical load. The production management module performs dynamic scheduling based on the predicted working progress under ergonomic constraints. The proposed system was applied to a parts-picking scenario, and its effectiveness was evaluated in terms of work monitoring, progress prediction, dynamic scheduling, and ergonomic assessment. This study demonstrates a proof-of-concept for introducing DH technology into DT-driven HRC for human-centered production systems.
Cytokines and IDDM: Implications for etiology and therapy (1998)

The evidence that human insulin-dependent diabetes mellitus (IDDM) is a T cell-mediated disease is well substantiated, and the use of transgenic technology to understand the Th1/Th2 paradigm will provide keys to attenuating pathogenic autoimmunity. Insofar as the role of Th1 cytokines in IDDM is concerned, interferon gamma is considered a critical player in the etiology, a proinflammatory role has been determined for IDDM, interleukin-2 is considered an "amplification" factor, and tumor necrosis factor-alpha presents dichotomous effects. Regarding the role of Th2 cytokines in IDDM, interleukin-4 is essential for immunoprotection and counterregulation of IDDM, and interleukin-10 plays immunoprotective and destructive roles. Therefore, Th1 and Th2 cytokines, when expressed individually in islets of Langerhans, have provided surprising results in manipulating the IDDM of transgenic NOD mice. The current data show that the same cytokine can produce either protective or pathological effects, depending upon the timing of its participation in the disease process. Of all the cytokines examined, IL-4 seems to be the likely candidate for preventing IDDM.
CPS fed linearly-tapered cavity backed slot antenna for 60 GHz applications (2010)

In this paper a cavity-backed linearly tapered slot antenna for 60 GHz operation is presented. Compared with other antennas, the footprint of the new antenna are reduced. This allows their usage in arrays at a finer pitch, thus reducing the footprint requirements of the whole array or allowing the usage of more antenna elements in an unscaled array. The antenna is shown to have a gain better than 6 dBi over a frequency range of 57…66 GHz and a very smooth pattern both in the E- and H-plane.
Synthesis and Characterization of Silicon Oxide Nanoflowers (2011)

Flower-like amorphous silicon oxide nanostructures were synthesized by a metal-catalyzed chemical vapor deposition method on Si (111) wafers, using SiCl4 as the source of Si and Au as catalyst in a flowing H2-5% Ar atmosphere. The nanostructures were characterized using field-emission scanning electron microscopy, transmission electron microscopy equipped with electron energy dispersive X-ray spectroscopy. Each flower-like nanostructure consists of many silicon oxide nanorods with smooth surface and uniform diameter. At early stage, the growth of the flower-like silicon oxide nanostructures was controlled by solid-liquid-solid and solid-vapor-liquid-solid mechanisms, and solid-vapor-liquid-solid and vapor-liquid-solid mechanisms at later stage. The silicon oxide nanoflowers show a photoluminescence emission band at 339 nm, revealing that the nanoflowers might have potential applications in the future optoelectronic device.
NIMG-39. CYTOSTATIC AGENTS COMBINED WITH TUMOR TREATING FIELDS (TTFIELDS) IN GLIOMA CELL LINES (2016)

TTFields are low-intensity intermediate frequency alternating electric fields that disrupt mitosis. This innovative treatment approach is approved for the treatment of patients with recurrent glioblastoma and a recent phase 3 study demonstrated superior progression free and overall survival in patients with newly diagnosed glioblastoma when TTFields were added to standard of care. The goal of this study was to determine possible additive or synergistic effects of TTFields in combination with different cytostatic agents that were chosen based on their known pre-clinical anti-glioma activity, oral administration, safety, and cost. For in vitro studies, U-118 MG and U-87 MG glioma cells were treated with TTFields. To assess whether adding Mefloquine, Metformin, Bumetanide, Minocycline, or Ganciclovir to TTFields affects the responsiveness of glioma cancer cells, we treated the cells with these agents alone and in combination with TTFields. The surviving fractions were determined using cell counts. Invasion assays were performed using modified Matrigel-coated Boyden chamber. Our results demonstrate that in vitro application of TTFields led to a significant reduction in cell counts as compared to untreated cells in both cell lines. Further reduction in the number of cells was achieved when TTFields were combined with Mefloquine, Metformin, or Ganciclovir. Combination of TTFields and Minocycline did not show enhanced efficacy in the tested cell line. The combined treatment of TTFields and Bumetanide, an agent that is known to inhibit cellular motility, did not lead to reduction in cell counts but resulted in significant inhibition of glioma cells invasion as compared to each treatment alone. These results suggest that TTFields in combinations with the tested cytostatic agents lead to enhanced inhibitory effect on glioma cells and could positively impact treatment outcome.
Synthesis and cytotoxicity of shikimate analogues. Structure:activity studies based on 1-crotonyloxymethyl-3R,4R,5R-trihydroxycyclohex-2-enone. (1992)

Syntheses are described for and structure:activity studies undertaken of the anti-tumour activity of (2-crotonyloxymethyl-(4R,5R,6R)-4,5,6-trihydroxycyclohex-2-+ ++enone) (1) and its analogues 1-crotonyloxymethyl-(3R,4S,5R)-3,4,5-trihydroxycyclohex-1-en e (3), 1-crotonyloxymethyl-(3R,4S,5S)-3,4,5-trihydroxycyclohexene (4) and 2-crotonyloxymethyl-2-cyclohexenone (5), which differ from 1 in the presence/absence of the cyclic keto group and/or the stereochemistry at one of the -OH bearing carbon atoms. None of the above compounds, including 1, directly inhibited glyoxalase I, isolated for the first time to homogeneity from rat Yoshida sarcomas and for which a purification protocol was developed. The apparent inhibition of glyoxalase I by 1 and 5 (but not detected for 4 or 3) could be explained by reaction of 1 and 5 with the glutathione present in the assay buffer and the consequent depletion of substrate. 1 and 5 were found to react readily with glutathione whereas 4 and 3 did not react. In vitro chemosensitivity studies against a panel of tumour cell lines of both mouse and human origin showed that in parallel with their thiol reactivity, 1 and 5 exhibited significant in vitro cytotoxicity whereas 4 and 3 did not. Concentrations of drug required to cause 50% cell kill (ID50 values) were in the range 0.5-19 microM (0.1-2.8 micrograms/ml) for 5, and 3-44 microM (0.7-10 micrograms/ml) for 1. The structural features causing the differences in antitumour effects were localized on this basis to the alpha,beta-unsaturated ketone linkage as opposed to the stereochemistry of the (trihydroxy) alcoholic sites.
Solving Sparse Assignment Problems on FPGAs (2022)

The assignment problem is a fundamental optimization problem and a crucial part of many systems. For example, in multiple object tracking, the assignment problem is used to associate object detections with hypothetical target tracks and solving the assignment problem is one of the most compute-intensive tasks. To enable low-latency real-time implementations, efficient solutions to the assignment problem is required. In this work, we present Sparse and Speculative (SaS) Auction, a novel implementation of the popular Auction algorithm for FPGAs. Two novel optimizations are proposed. First, the pipeline width and depth are reduced by exploiting sparsity in the input problems. Second, dependency speculation is employed to enable a fully pipelined design and increase the throughput. Speedups as high as 50 × are achieved relative to the state-of-the-art implementation for some input distributions. We evaluate the implementation both on randomly generated datasets and realistic datasets from multiple object tracking.
대학 독서실에서 발생하는 소음의 특성과 사용자 의식 분석 - C 대학교의 독서실을 대상으로 - (2010)

Reading room in the university is one of necessary facilities that university student must use. It is, therefore, very important to make reading room comfortable acoustically not only to minimize the annoyance to the users but also to provide efficiency in studying. Present study aims to investigate...
Investigation of boron diffusion in polysilicon and its application to the design of p-n-p polysilicon emitter bipolar transistors with shallow emitter junctions (1991)

Ion implantation of boron into undoped polysilicon is utilized. The main goals are to characterize the diffusion of implanted boron from polysilicon, and to correlate the diffusion behavior with the electrical properties of shallow (<500 AA) p-n-p polysilicon emitter bipolar transistors. It is shown that diffusion and electrical activity problems are encountered with boron polysilicon emitters which are not present with arsenic. Base current and emitter resistance are measured on shallow p-n-p polysilicon emitter transistors, and it is shown that the use of a deliberately grown interfacial oxide layer can decrease the base current by a factor of 10 and increase the emitter resistance by a factor of around 2. Comparisons with identical n-p-n polysilicon emitter transistors show that the modeled interfacial oxide, tunneling parameters for n-p-n and p-n-p devices are inconsistent.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Genome-wide detection of sRNA targets with rNAV (2013)

The central dogma in molecular biology postulated that ‘DNA makes RNA makes protein’, however this dogma has been recently extended to integrate new biological activities involving small bacterial noncoding RNAs, called sRNAs. Accordingly, increasing attention has been given to these molecules over the last decade and related experimental works have shown a wide range of functional activities for these molecules. In this paper, we present rNAV (for rna NAVigator), a new tool for the visual exploration and analysis of bacterial sRNA-mediated regulatory networks. rNAV has been designed to help bioinformaticians and biologists to identify, from lists of thousands of predictions, pertinent and reasonable sRNA target candidates for carrying out experimental validations. We propose a list of dedicated algorithms and interaction tools that facilitate the exploration of such networks. These algorithms can be gathered into pipelines which can then be saved and reused over several sessions. To support exploration awareness, rNAV also provides an exploration tree view that allows to navigate through the steps of the analysis but also to select the sub-networks to visualize and compare. These comparisons are facilitated by the integration of multiple and fully linked views. We demonstrate the usefulness of our approach by a case study on Escherichia coli bacteria performed by domain experts.
Laboratory measurements of ground water leaching and transport of pollutants produced during underground coal gasification (1978)

Two series of laboratory experiments dealing with release and migration of pollutants produced during underground coal gasification are discussed. In the first series of experiments coal ash samples prepared by heat treatment to 1000, 1100, and 1200/sup 0/C have been subjected to water leaching at 23/sup 0/C. The leachate, was analyzed for concentrations of Ca, K, Al, Ba, Fe, SO/sub 4/, OH, Mg, and Na ions likely to be present. The data provide a quantitative picture of the amount and rate of release of these various elements from coal ash left underground. Furthermore, the measured concentrations of the various elements studied in the laboratory experiments are generally in good agreement with results from ground water measurements conducted at the LLL Hoe Creek 1 coal gasification site. A second set of experiments deals with transport of pollutants away from a gasification site by the natural ground water flow through the coal seam. Two idealized cases have been studied: transport of NaBr and transport of phenol. The experiments were carried out by flowing solutions of these materials through a 1.5 m packed column of coal and measuring the breakthrough curves at various points along the column. The results are analyzed using amore » simple one-dimensional transport model. The results show the strong adsorption of phenol by the coal (K/sub d/ = 40). These results are compared with recent measurements of the cocentration of phenolic material left near an underground gasifier.« less
Precompensation and windowing for nonlinear frequency-division multiplexing (2017)

The impact of temporal broadening induced by dispersion in nonlinear frequency-division multiplexing systems is investigated through simulations. Two techniques are investigated to halve the guard time between symbol bursts and reduce the size of the processing window at the receiver, increasing spectral efficiency and reducing computational complexity.
Dielectric Studies of Bi2MoO6/Graphene Oxide and La-Doped Bi2MoO6/Graphene Oxide Nanocomposites (2021)

The mixed metal oxides Bi2MoO6 and La-doped Bi2MoO6 were prepared by the sol–gel method. Then, varying quantities of the as-prepared mixed metal oxides were blended with graphene oxide (GO), employing sonication, to obtain Bi2MoO6/GO (BM/GO) and La-Bi2MoO6/GO (LBM/GO) nanocomposites. These prepared materials were characterized by different techniques such as thermal gravimetric analysis (TGA), X-ray diffraction (XRD), Brunauer-Emmett-Teller (BET), X-ray photoelectron spectroscopy (XPS), scanning electron microscope (SEM), and transmission electron microscopy (TEM). Dielectric properties were studied by using a precision impedance analyzer. Dielectric constant and loss tan of the synthesized composites were studied as a function of frequency by using a precision impedance analyzer. Overall, the dielectric constant (ɛ’) observed for the LBM/GO composites was higher than that of BM/GO.
247. Characterization of Oversized rAAV Vectors for Human FVIII Gene Transfer (2015)

Severe hemophilia A patients with <1% coagulation activity are currently managed by infusions of recombinant factor VIII (FVIII). As periodic infusions generate trough levels of FVIII that are non-optimal, painful and debilitating joint deteriorations caused by spontaneous joint bleeds remain prevalent. Clinical trials have demonstrated that a single intravenous injection of rAAV vectors encoding FIX in hemophilia B patients can provide steady-state factor IX levels for > 4 years and consequent reduction or elimination of the need for frequent factor infusions. Similar rAAV-mediated gene transfer for hemophilia A patients is challenging due to the size of the FVIII cDNA that when combined with the necessary transcriptional elements exceeds the rAAV packaging limit of 4.7 kb. To test the feasibility of rAAV-mediated gene therapy for hemophilia A, we generated several oversized FVIII expression cassettes of different lengths and containing human B-domain deleted FVIII cDNA. These constructs were used to produce rAAV vectors by triple transfection and virus quality and yield were analyzed. Characterization of the packaged vector genomes (VGs) by Southern blot showed that the majority of genomes were 4.7 kb in size (with some being larger) and that the vector yield was affected by VG size. The vectors were also administered intravenously into C57BL/6 mice to test in vivo potency. Plasma FVIII levels were measured for 7 months post-treatment and at the end of the study, levels of FVIII mRNA and liver VG copies were quantitated. The data showed intact expression cassettes and comparable number of VG copies in liver among the vectors. Also, the higher liver mRNA levels correlated with higher plasma FVIII levels indicating that expression levels were a limiting factor. Lastly, the rAAV vector ranking was similar to ranking of plasmid expression cassettes (hydrodynamic injections) in vivo. These studies confirmed the viability of oversized rAAV vectors as an approach for the treatment of severe hemophilia A.
Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis (2017)

Group 2 innate lymphoid cells (ILC2s) are involved in human diseases, such as allergy, atopic dermatitis and nasal polyposis, but their function in human cancer remains unclear. Here we show that, in acute promyelocytic leukaemia (APL), ILC2s are increased and hyper-activated through the interaction of CRTH2 and NKp30 with elevated tumour-derived PGD2 and B7H6, respectively. ILC2s, in turn, activate monocytic myeloid-derived suppressor cells (M-MDSCs) via IL-13 secretion. Upon treating APL with all-trans retinoic acid and achieving complete remission, the levels of PGD2, NKp30, ILC2s, IL-13 and M-MDSCs are restored. Similarly, disruption of this tumour immunosuppressive axis by specifically blocking PGD2, IL-13 and NKp30 partially restores ILC2 and M-MDSC levels and results in increased survival. Thus, using APL as a model, we uncover a tolerogenic pathway that may represent a relevant immunosuppressive, therapeutic targetable, mechanism operating in various human tumour types, as supported by our observations in prostate cancer.Group 2 innate lymphoid cells (ILC2s) modulate inflammatory and allergic responses, but their function in cancer immunity is still unclear. Here the authors show that, in acute promyelocytic leukaemia, tumour-activated ILC2s secrete IL-13 to induce myeloid-derived suppressor cells and support tumour growth.
Copy Number Analysis in EBV-Positive Nodal Peripheral T Cell Lymphoma, Unspecified (2013)

Copy number alteration was investigated in three cases of EBV + nodal peripheral T cell lymphoma of cytotoxic phenotype using Agilent array comparative genomic hybridization platform. While no recurrent abnormality among three cases was identified, genomic abnormalities involving 9p23.3, 16p13.3, and 7q34 were overlapped with changes reported in other type of NK or T cell lymphomas previously. Chromosomal region 9p23.3 contains CDKN2A and CDKN2B which are frequently mutated or deleted in various types of cancer and may be a target to find genes associated with the pathogenesis of EBV-positive nodal peripheral T cell lymphoma.