gebhart/patrepeval huggingface dataset:
Fatty Acid Binding Protein as an Early Plasma Marker of Myocardial Ischemia and Risk Stratification (2003)

Biochemical markers of myocardial injury are universally accepted as important determinants for the diagnosis of patients with suspected acute myocardial infarction (AMI), especially in those cases in which electrocardiographic (ECG) changes are equivocal or absent (1,2). In the last decade, interest in these biochemical markers has increased for two reasons. First, the introduction of new therapeutic strategies has called for earlier and more appropriate diagnosis of patients admitted to the emergency room with chest pain, so as to begin the proper therapy as early as possible. Second, several new plasma markers have been introduced, and some (e.g., cardiac troponin T [eTnT]) allow for the assessment of patients with not only MI but also unstable angina and prolonged chest pains, and even provide prognostic value (3).KeywordsAcute Myocardial InfarctionReceiver Operating Characteristic CurveMyocardial InjuryFatty Acid Binding ProteinMyocardial Infarct SizeThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
DNA Content in Non-Hodgkin's Lymphoma: Comparison between flow cytometry and cytogenetics in fresh and paraffin-embedded tissue (1994)

DNA content of 36-non-Hodgkin's lymphomas was analyzed by flow cytometry (FCM) and cytogenetics (CG), 21 in fresh and 15 in paraffin-embedded tissue. The results of both techniques were coincident in 60% of the fresh tissue samples and in 45% of the paraffin-embedded ones, the reason for this difference could be the poor resolution of DNA histograms from paraffin-embedded tissue. All samples judged as aneuploid by FCM were aneuploid also by CG. Some samples with a hyperdiploid population by CG gave a diploid population by FCM with a 'false' high DNA-synthesis (S) fraction. From a technical point of view, CG and FCM have to be performed on the same fresh tissue.
3D piecewise planar object model for robotics manipulation (2011)

Man-made environments are abundant with planar surfaces which have attractive properties for robotics manipulation tasks and are a prerequisite for a variety of vision tasks. This work presents automatic on-line 3D object model acquisition assuming a robot to manipulate the object. Objects are represented with piecewise planar surfaces in a spatio-temporal graph. Planes once detected as homographies are tracked and serve as priors in subsequent images. After reconstruction of the planes the 3D motion is analyzed and initial object hypotheses are created. In case planes start moving independently a split event is triggered, the spatio-temporal object graph is traced back and visible planes as well as occluded planes are assigned to the most probable split object. The novelty of this framework is to formalize Multi-body Structure-and-Motion (MSaM), that is, to segment interest point tracks into different rigid objects and compute the multiple-view geometry of each object, with Minimal Description Length (MDL) based on model selection of planes in an incremental manner. Thus, object models are built from planes, which directly can be used for robotic manipulation.
Coherent Transients in the Femtosecond Photoassociation of Ultracold Molecules (2008)

We demonstrate the photoassociation of ultracold rubidium dimers using coherent femtosecond pulses. Starting from a cloud of ultracold rubidium atoms, electronically excited rubidium molecules are formed with shaped photoassociation pump pulses. The excited state molecules are projected with a time-delayed probe pulse onto molecular ion states which are detected in a mass spectrometer. Coherent transient oscillations of the excited state population are observed in the wings of the pump pulse, in agreement with the time-dependent solution of the Schrödinger equation of the excitation process.
GaN Schottky diodes for proton beam monitoring (2018)

We have demonstrated that GaN Schottky diodes can be used for high energy (64.8 MeV) proton detection. Such proton beams are used for tumor treatment, for which accurate and radiation resistant detectors are needed. Schottky diodes have been measured to be highly sensitive to protons, to have a linear response with beam intensity and fast enough for the application. Some photoconductive gain was found in the diode leading to a good compromise between responsivity and response time. The imaging capability of GaN diodes in proton detection is also demonstrated.
Synthesis and Reactions of 1,4,4a,5,8,8a-Hexahydro-1,4-Methano-5,8-Ethenonaphthalene (1988)

Abstract The preparation of the titled compound 1 is described. Its photochemical reaction and its formation of a molybdenum carbonyl complex are also reported.
A new tricarboxylic acid anhydride from Paecilomyces variotii (1980)

D. C. Aldridge, R. M. Carman and R. B. Moore, J. Chem. Soc., Perkin Trans. 1, 1980, 2134 DOI: 10.1039/P19800002134
47. Synthesis of uronic acids. Part II. 2 : 3 : 4-Trimethyl derivatives of mannuronic, glucuronic, and galacturonic acids (1944)

F. Smith, M. Stacey and P. I. Wilson, J. Chem. Soc., 1944, 131 DOI: 10.1039/JR9440000131
Gels in soap stabilized emulsions (1976)

Abstract In some soap stabilized liquid paraffin emulsions a correlation has been found between emulsion type and the contact angle of the soap gel (the stabilizing agent) at the o/w interface. Two unrelated series of emulsions have been prepared, one series being stabilized by magnesium oleate gels and the other series by ammonium oleate gels. The soap gels were prepared by double decomposition and suppression of ionization respectively. Unlike the magnesium oleate system no inversion to w/o emulsions occurred with the ammonium oleate series. This dissimilarity is predicted from differences in the contact angles of the soap gels at the o/w interface.
Voltage Controlled Polarizer Using Cholesteric Liquid Crystals (1983)

Abstract We report the optical behavior of a cholesteric liquid crystal cell under a dc electric field. The peculiar features of the cell make it possible to use it as a voltage controlled polarizer for which an international patent is pending.
Production of polyhydroxyalkanoates through an integrated anaerobic-aerobic process fed with olive mill wastewaters as a renewable resource (2007)

Polyhydroxyalkanoates (PHAs) are biopolimers whose properties and applicability are quite similar to these of polypropylene. However, their production on the large scale is actually too expansive. In this research, an innovative biotechnological low-cost PHA producing process, consisting of three stages, is being studied. The aim of the first anaerobic stage is to obtain an effluent rich in volatile fatty acids (VFAs), which represents the substrate for microbial PHA production, through the acidogenic fermentation of olive mill wastewaters (OMWs), which are the liquid wastes of olive oil producing processes and are generally considered effluents of high environmental concern. In the second aerobic stage, the anaerobic effluent is fed to a Sequencing Batch Reactor (SBR) where microbial populations able to transform VFAs in PHAs are selected. In the third aerobic stage, the excess sludge from the second stage is fed with the effluent of the acidogenic fermentation in order to increase its PHA content up to the maximum value. Packed-bed biofilm reactor technology was chosen to develop the anaerobic first stage. Packing material and temperature parameters were studied by developing 4 identically-configured PBBRs: two of them were filled with granular activated carbon (GAC), the other two with ceramic cubes (VS); one reactor for each material was thermostated at 35°C, the other two at 55°C. 2 one-month batch experiments were previously carried out by feeding the reactors with a diluted and amended OMW, so that the initial waste COD was 6.33 g/l. The higher VFA production was observed within the second experiment in the SVS-PBBR operating at 35°C, where a conversion of the initial COD in VFAs of about the 60% was observed. Acetic acid was the main component of the VFA mixtures collected from all the PBBRs. Significant concentrations of both propionic and butirric acid were also observed.. Then, the PBBRs were forced to operate in continuous conditions and fed with an organic load of about 8 g/l/d. GAC-PBBR operating at 35°C gave rise to the highest VFA production, even if the COD conversion in VFAs was lower than the one reported above for batch experiments, due to a significant methanogenic activity. Higher organic loads will be fed to the 4 PBBRs in order to optimize the OMW acidogenic fermentation stage. The second and third stages of the process were studied in aerobic sequencing batch reactors, fed with a synthetic mixture of acetic (85% on a COD basis) and propionic (15 %) acids. In particular the effect of the pH in the second stage was studied. Three runs were carried out at three different pH values: 7.5, 8.5 and 9.5. The highest substrate removal rates and polymer production rates were obtained at pH 8.5. Under these conditions, PHAs were produced at a rate of approximately 350 mgCOD/gCOD/h, with a storage yield of 45% (as COD). The produced polymer was a P(HB-HV) co-polymer, with 13% (mol/mol) HV content.
Persistent Impairment of Platelet Aggregation following Cessation of a Short-course Dietary Supplementation of Moderate Amounts of N-3 Fatty Acid Ethyl Esters (1999)

The duration of the effect of a short-course (1-mo twice-daily) supplementation of moderate amounts (2.28 g) of n-3 fatty acid ethyl esters (FA) on platelet lipid composition and aggregation was compared with that of olive oil (3 g/d) supplementation in 14 healthy volunteers. The FA preparation employed contained eicosapentaenoic acid (EPA) and docosahexaenoic acids (DHA) in a ratio of 1:1.4. A marked rise (p <0.05) in the plasma and platelet content of EPA and DHA, and minimal changes in the content of arachidonic acid (AA) were documented at withdrawal of the n-3 FA supplementation. EPA/AA and DHA/AA ratios in platelet phospholipids showed that the FA accumulation persisted 8-12 wks after stopping the supplementation (p <0.05). The aggregation of platelets in response to collagen or ADP, and thromboxane B2 (TXB2) formation were impaired at withdrawal. The impaired aggregation lasted 8-12 weeks (p always <0.05), whereas TXB2 formation returned to basal values 4 weeks after stopping the n-3 supplementation. No correlation was found between impaired aggregation and TXB2 formation. In contrast, the impaired sensitivity to ADP (p = 0.036) and, to a lesser extent, to collagen (p = 0.068) were related to changes in the intracellular pH (pHi) of the Na+/H+ reverse transport. No changes in platelet composition or function were observed either during or following olive oil supplementation. These results document a long-lasting impairment of platelet sensitivity to ADP and collagen; changes in the pHi values of the Na+/H+ reverse transport, and a simultaneous persistent accumulation of EPA and DHA in platelet phospholipids, after stopping a short-course dietary supplementation of moderate amounts of n-3 fatty acid ethyl esters.
Synthesis and through-space charge transfer of dioctyloxy diperfluorohexyl substituted [2.2]paracyclophane-1,9-diene (2014)

Paracyclophanedienes containing dioctyloxy and diperfluorohexyl substituents have been synthesized in three steps from substituted dithia[3.3]paracyclophanes and the structures were fully characterized by nuclear magnetic resonance spectroscopy. A mixture of pseudo-geminal and pseudo-ortho diastereomers is produced and the pure compounds can be simply obtained by flash column chromatography using hexane as an eluent. The pseudo-geminal isomer exhibited more efficient through space charge transfer between electron donating and withdrawing substituents than the pseudo-ortho isomer. The absorption and photoluminescence spectra of both pseudo-geminal and pseudo-ortho diastereomers in a more polar solvent show the solvatochromism of the through-space electron transfer between dioctyloxy substituted phenyl and diperfluorohexyl substituted phenyl rings.
Fully Automatic Visualisation of Overlapping Sets (2009)

Abstract Visualisation of taxonomies and sets has recently become an active area of research. Many application fields now require more than a strict classification of elements into a hierarchy tree. Euler diagrams, one of the most natural ways of depicting intersecting sets, may provide a solution to these problems. In this paper, we present an approach for the automatic generation of Euler‐like diagrams. This algorithm differs from previous approaches in that it has no undrawable instances of input, allowing it to be used in systems where the output is always required. We also improve the readability of Euler diagrams through the use of Bézier curves and transparent coloured textures. Our approach has been implemented using the Tulip platform. Both the source and executable program used to generate the results are freely available.
X-Band Ferrite Microstrip Limiter Based on Improved Nonlinear Loss Model for High-Power Microwave Application (2022)

An improved ferrite nonlinear (NL) loss theory is developed for polycrystal ferrite microstrip limiters upon the high-power microwave (HPM) environment. The NL critical threshold equation and equivalent loss model are derived from the field coupling mechanism between spin waves and microwave pulse. Thus, the equivalent NL loss behavior with the microwave waveform parameters (pulse duration and power) is implanted in the ferrite limiter model to perform the numerical simulation through the commercial electromagnetic tool. The measured limiting data at pulse duration with 60, 80, 100, and 200 ns are in good agreement with the equivalent simulation results.
Oxygen Breathing Affects 3′-Deoxy-3′-18F-Fluorothymidine Uptake in Mouse Models of Arthritis and Cancer (2012)

Oxygen-breathing conscious mice sustained respiratory acidosis and, consequently, reduced cell proliferation and (18)F-FLT uptake in arthritic ankles and CT26 colon carcinomas. Thus, we suggest the use of air instead of oxygen breathing for (18)F-FLT PET measurements.
Purification of Aqueous Suspensions from Colloidal Particles by Electro-Adsorption on Porous Carbon Electrodes (1987)

Abstract The electrically induced adsorption of carboxylated colloidal particles from aqueous suspension on a carbon electrode was studied. Due to high colloid to electrode charge density ratio, adsorption is effected only to a small extent when the electrode potential is varied within the double layer potential range. At extreme potentials where water is involved in Faradaic reactions, colloid adsorption occurs due to pH variations. The process may be attractive for purification of suspensions from fine particles since no chemicals have to be added in order to induce adsorption or desorption of the colloid.
Erratum: Corrigendum: Cannabinoids and Capsaicin Improve Liver Function Following Thioacetamide-Induced Acute Injury in Mice (2009)

Corrigendum: Cannabinoids and Capsaicin Improve Liver Function Following Thioacetamide-Induced Acute Injury in Mice
Clinical profile and outcome of isolated pulmonary embolism: a systematic review and meta-analysis (2023)

None.
Pentelligence (2018)

Digital pens emit ink on paper and digitize handwriting. The range of the pen is typically limited to a special writing surface on which the pen's tip is tracked. We present Pentelligence, a pen for handwritten digit recognition that operates on regular paper and does not require a separate tracking device. It senses the pen tip's motions and sound emissions when stroking. Pen motions and writing sounds exhibit complementary properties. Combining both types of sensor data substantially improves the recognition rate. Hilbert envelopes of the writing sounds and mean-filtered motion data are fed to neural networks for majority voting. The results on a dataset of 9408 handwritten digits taken from 26 individuals show that motion+sound outperforms single-sensor approaches at an accuracy of 78.4% for 10 test users. Retraining the networks for a single writer on a dataset of 2120 samples increased the precision to 100% for single handwritten digits at an overall accuracy of 98.3%.
Small molecule enhancers of autophagy for neurodegenerative diseases (2008)

Neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, prion diseases and polyglutamine disorders, including Huntington's disease and various spinocerebellar ataxias, are associated with the formation of protein aggregates. These aggregates and/or their precursors are thought to be toxic disease-causing species. Autophagy is a major degradation pathway for intracytosolic aggregate-prone proteins, including those associated with neurodegeneration. It is a constitutive self-degradative process involved both in the basal turnover of cellular components and in response to nutrient starvation in eukaryotes. Enhancing autophagy may be a possible therapeutic strategy for neurodegenerative disorders where the mutant proteins are autophagy substrates. In cell and animal models, chemical induction of autophagy protects against the toxic insults of these mutant aggregate-prone proteins by enhancing their clearance. We will discuss various autophagy-inducing small molecules that have emerged in the past few years that may be leads towards the treatment of such devastating diseases.
Gate tunable non-linear currents in bilayer graphene diodes (2012)

Electric transport of double gated bilayer graphene devices is studied as a function of charge density and bandgap. A top gate electrode can be used to control locally the Fermi level to create a pn junction between the double-gated and single-gated region. These bilayer graphene pn diodes are characterized by non-linear currents and directional current rectification, and we show the rectified direction of the source-drain voltage can be controlled by using gate voltages. A systematic study of the pn junction characteristics allows to extract a gate-dependent bandgap value which ranges from 0 meV to 130 meV.
Synthesis of High Molecular Weight Copolymers by Ruthenium-Catalyzed Step-Growth Copolymerization of Acetophenone with .alpha.,.omega.-Dienes (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of High Molecular Weight Copolymers by Ruthenium-Catalyzed Step-Growth Copolymerization of Acetophenone with .alpha.,.omega.-DienesHongjie Guo, Guohong Wang, Mark A. Tapsak, and William P. WeberCite this: Macromolecules 1995, 28, 16, 5686–5687Publication Date (Print):July 1, 1995Publication History Published online1 May 2002Published inissue 1 July 1995https://doi.org/10.1021/ma00120a042RIGHTS & PERMISSIONSArticle Views266Altmetric-Citations51LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (259 KB) Get e-Alerts Get e-Alerts
Widespread occurrence of Mycobacterium tuberculosis DNA from 18th–19th century Hungarians (2003)

A large number (265) of burials from 1731-1838 were discovered in sealed crypts of the Dominican Church, Vác, Hungary in 1994. Many bodies were naturally mummified, so that both soft tissues and bones were available. Contemporary archives enabled the determination of age at death, and the identification of family groups. In some cases, symptoms before death were described and, occasionally, occupation. Initial radiological examination of a small number of individuals had indicated calcified lung lesions and demonstrable acid-fast bacteria suggestive of tuberculosis infection. Tuberculosis was endemic in 18th-19th century Europe, so human remains should contain detectable Mycobacterium tuberculosis complex (MTB) DNA, enabling comparisons with modern isolates. Therefore, a comprehensive examination of 168 individuals for the presence of MTB DNA was undertaken. Specific DNA amplification methods for MTB showed that 55% of individuals were positive and that the incidence varied according to age at death and sampling site in the body. Radiographs were obtained from 27 individuals and revealed an association between gross pathology and the presence of MTB DNA. There was an inverse relationship between PCR positivity and MTB target sequence size. In some cases, the preservation of MTB DNA was excellent, and several target gene sequences could be detected from the same sample. This information, combined with MTB DNA sequencing data and molecular typing techniques, will enable us to study the past epidemiology of TB infection, and extends the timeframe for studying changes in molecular fingerprints.
TNF‐α stimulates caspase‐3 activation and apoptotic cell death in primary septo‐hippocampal cultures (2001)

Primary septo-hippocampal cell cultures were incubated in varying concentrations of tumor necrosis factor (TNF-alpha; 0.3-500 ng/ml) to examine proteolysis of the cytoskeletal protein alpha-spectrin (240 kDa) to a signature 145 kDa fragment by calpain and to the apoptotic-linked 120-kDa fragment by caspase-3. The effects of TNF-alpha incubation on morphology and cell viability were assayed by fluorescein diacetate-propidium iodide (FDA-PI) staining, assays of lactate dehydrogenase (LDH) release, nuclear chromatin alterations (Hoechst 33258), and internucleosomal DNA fragmentation. Incubation with varying concentrations of TNF-alpha produced rapid increases in LDH release and nuclear PI uptake that were sustained over 48 hr. Incubation with 30 ng/ml TNF-alpha yielded maximal, 3-fold, increase in LDH release and was associated with caspase-specific 120-kDa fragment but not calpain-specific 145-kDa fragment as early as 3.5 hr after injury. Incubation with the pan-caspase inhibitor, carbobenzosy- Asp-CH(2)-OC (O)-2-6-dichlorobenzene (Z-D-DCB, 50-140 microM) significantly reduced LDH release produced by TNF-alpha. Apoptotic-associated oligonucleosomal-sized DNA fragmentation on agarose gels was detected from 6 to 72 hr after exposure to TNF-alpha. Histochemical changes included chromatin condensation, nuclear fragmentation, and formation of apoptotic bodies. Results of this study suggest TNF-alpha may induce caspase-3 activation but not calpain activation in septo-hippocampal cultures and that this activation of caspase-3 at least partially contributes to TNF-alpha-induced apoptosis.