gebhart/patrepeval huggingface dataset:
Analysis of steering control in vehicles with two independent left and right traction wheels (1991)

Based on the kinematic studies of motion for a vehicle equipped with a pair of motorized wheels which, by having appropriate velocities, can provide traction forces as well as steering action, a steering control strategy is derived. The angular velocities for the right and left wheels are considered, the two control inputs which cause a system to follow a desired trajectory. Assuming these inputs to be linear functions of the two errors associated with path tracking problem (position and orientation errors), through an appropriate Lyapunov function, a control policy is determined. The path tracking behaviour of a mobile robot using such a control law is demonstrated by computer simulation.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Functional changes in rheumatoid fibroblast-like synovial cells through activation of peroxisome proliferator-activated receptor γ-mediated signalling pathway (2002)

Peroxisome proliferator-activated receptor gamma (PPARgamma) is a ligand dependent transcriptional factor known to be a regulator of adipogenesis. Recent studies have also shown that stimulation of PPARgamma inhibits the transcriptional activities of other nuclear factors and down-regulates proinflammatory cytokine synthesis in T cells and monocytes. We examined, in the present study, the functional significance of PPARgamma expressed in fibroblast-like synovial cells (FLS) isolated from patients with rheumatoid arthritis (RA). Incubation of FLS with a synthetic PPARgamma ligand, troglitazone, inhibited endogenous production of TNF-alpha, IL-6 and IL-8, as well as matrix metalloprotease-3 (MMP-3), without inducing apoptosis of the cells. The gelatinase activity of FLS culture media was also inhibited by troglitazone. Electrophoretic mobility shift assay (EMSA) showed a significant reduction in the DNA binding activity of NF-kappaB in troglitazone-treated FLS in response to TNF-alpha or IL-1beta. Moreover, long-term cultivation of FLS with troglitazone resulted in morphological changes with marked lipid accumulation in these cells. Our results show a negative regulatory function for PPARgamma on cytokine and MMP production together with inhibition of cytokine-mediated inflammatory responses in rheumatoid synovial cells. Our results also suggest that FLS could differentiate into adipocyte-like cells in the presence of proper stimulatory signals including PPARgamma.
Limited Feedback Unitary Precoding for Spatial Multiplexing Systems (2005)

Multiple-input multiple-output (MIMO) wireless systems use antenna arrays at both the transmitter and receiver to provide communication links with substantial diversity and capacity. Spatial multiplexing is a common space-time modulation technique for MIMO communication systems where independent information streams are sent over different transmit antennas. Unfortunately, spatial multiplexing is sensitive to ill-conditioning of the channel matrix. Precoding can improve the resilience of spatial multiplexing at the expense of full channel knowledge at the transmitter-which is often not realistic. This correspondence proposes a quantized precoding system where the optimal precoder is chosen from a finite codebook known to both receiver and transmitter. The index of the optimal precoder is conveyed from the receiver to the transmitter over a low-delay feedback link. Criteria are presented for selecting the optimal precoding matrix based on the error rate and mutual information for different receiver designs. Codebook design criteria are proposed for each selection criterion by minimizing a bound on the average distortion assuming a Rayleigh-fading matrix channel. The design criteria are shown to be equivalent to packing subspaces in the Grassmann manifold using the projection two-norm and Fubini-Study distances. Simulation results show that the proposed system outperforms antenna subset selection and performs close to optimal unitary precoding with a minimal amount of feedback.
Adaptive Transform Coding And Image Quality (1986)

A review of adaptive image transform coding techniques is given. Adaptive techniques are superior to nonadaptive procedures; however, their implementation requires a significant degree of added complexity. A major aspect of adaptive transform coding is the understanding and utilization of the local statistical structure of the image. Rate adaptive communication and buffer feedback are also important aspects of adaptive coding procedures. The discussion emphasizes the image quality aspect of the coding process.
Chemo-type of essential oil of Ocimum basilicum L. from DR Congo and relative in vitro antioxidant potential to the polarity of crude extracts (2016)

To carry out a phyto-chemical characterization of essential oil from Ocimum basilicum L. (O. basilicum) harvested in DR Congo and to assess the antioxidant potential of crude extracts with respect to the polarity for comparison reason. The phyto-chemical characterization of essential oil produced by hydro-distillation was performed by coupled gas chromatography-mass spectrometer analysis and the antioxidant potential evaluation by in vitro 2,2-diphenyl-1-picrylhydrazyl free radical scavenging activity method. A previously weighed amount of fresh leaves of O. basilicum produced 0.65% of essential oil that led to the identification of a set of 84.44% out of 99.98% as major compounds (> 1.5%). The chemo-type of this essential oil was linalool-methyl chavicol. Chemical components of oil were characterized by oxygenated aromatic hydrocarbons (46.00%) and oxygenated monoterpenes (26.75%). With respect to the amount of components, methyl chavicol also known as estragole (35.72%) constituted the very large quantity afterward linalool (21.25%) and then epi-α-cadinol (8.02%), α-bergamotene (6.56%), eugenol (4.60%), 1,8-cineole (4.04%), germacrene D (2.06%), thymol (1.64%), and (E)-citral (1.55%), respectively. Essential oil exhibited antioxidant potential and IC50 = (1.180 ± 0.015) mg/mL. Non-polar crude extracts yields were low compared to the one of polar extracts. Only methanol and ethyl acetate had considerably manifested antioxidant potential with IC50 values equal to (0.025 ± 0.013) mg/mL and (0.085 ± 0.012) mg/mL, respectively. As concerns to IC50 values, essential oil was less active than methanol and ethyl acetate extracts. The methanol crude extract exhibited the highest activity. Non-polar extracts showed insignificant radical scavenging ability that did not allow assessing IC50 values. These results highlighted the occurrence of antioxidant potential compounds in polar media. Essential oil and crude extracts of O. basilicum growing in DR Congo can be advocated as natural sources of antioxidant potential compounds not only in food but also in pharmaceutical industries. The high antioxidant potential of polar crude extracts highlights antioxidant character of its composition particularly butyl stearate and rosmarinic acid we isolated and identified, respectively in the methanol crude extract.
Cellular and Engineered Organoids for Cardiovascular Models (2022)

An ensemble of in vitro cardiac tissue models has been developed over the past several decades to aid our understanding of complex cardiovascular disorders using a reductionist approach. These approaches often rely on recapitulating single or multiple clinically relevant end points in a dish indicative of the cardiac pathophysiology. The possibility to generate disease-relevant and patient-specific human induced pluripotent stem cells has further leveraged the utility of the cardiac models as screening tools at a large scale. To elucidate biological mechanisms in the cardiac models, it is critical to integrate physiological cues in form of biochemical, biophysical, and electromechanical stimuli to achieve desired tissue-like maturity for a robust phenotyping. Here, we review the latest advances in the directed stem cell differentiation approaches to derive a wide gamut of cardiovascular cell types, to allow customization in cardiac model systems, and to study diseased states in multiple cell types. We also highlight the recent progress in the development of several cardiovascular models, such as cardiac organoids, microtissues, engineered heart tissues, and microphysiological systems. We further expand our discussion on defining the context of use for the selection of currently available cardiac tissue models. Last, we discuss the limitations and challenges with the current state-of-the-art cardiac models and highlight future directions.
Reliability of die attached AlN-DBC module using Zn-Sn high temperature lead-free solders (2008)

Interfacial reaction and reliability of Si die attached joints with Zn-xSn (chi= 20, 30, 40 wt%) were investigated, and Pb-5wt%Sn, and Au-20wt% were compared as a typical high temperature solder alloy. The joining strength of Cu/solder/Cu joints was investigated using the as soldered joints and thermal cycled joints up to 2000 cycles. At the interface with Si die coated with Au/TiN thin layers, the TiN layer did not react with the solder and worked as a good protective layer. At the interface with Cu, for Zn-Sn solders, CuZn <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">5</sub> and Cu <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">5</sub> Zn <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">8</sub> IMC layers was confirmed. Au-20Sn and Pb-5Sn solder forms zeta-Au <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">5</sub> Sn and Cu <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> Sn IMC layers at the interface with Cu, respectively. For improving the joint reliability, TiN layer was proposed as a protective layer and was applied to the DBC substrates. For the die attached joints on DBC substrates coated with Au/TiN thin layers, no fatigue crack has been found until 1000 cycles of thermal cycling test. The joining strength of the Cu/solder/Cu joints with Zn-Sn solder was about 30~34 MPa, which was higher than that of Pb-5Sn solder (26.2 MPa). For the thermal cycled Cu/solder/Cu joints up to 2000cycles, Zn-Sn solder also shows the higher joining strength than that of Pb-5Sn solder.
Long-term improvement of air quality associated with lung function benefits in Chinese young adults: A quasi-experiment cohort study (2022)

Long-term improvement of air quality can improve lung function among young adults. Stricter policies on improving air quality are needed to protect human health.
Composition of Essential Oil from Tagetes minuta and its Cytotoxic, Antioxidant and Antimicrobial Activities (2014)

The essential oil from the leaves of Tagetes minuta L., growing wild in Yemen, was obtained by hydrodistillation and analyzed by gas chromatography-mass spectrometry. A total of 28 compounds were identified representing 74.2% of total oil composition. Major components of the essential oil were (Z)-ocimenone (15.9%), (E)-ocimenone (34.8%), (Z)-beta-ocimene (8.3%), limonene (2.3%), (Z)-tagetone (1.8%), dihydrotagetone (1.4%) and an unidentified dimethylvinylketone derivative (20.6%). The oil showed moderate cytotoxic activity against MCF-7 breast tumor cells, with an IC50 of 54.7 +/- 6.2 microg/mL. In the DPPH radical scavenging assay, T. minuta oil showed potent antiradical activity with an IC50 value of 36 microg/mL. Antimicrobial activity was also investigated on several microorganisms, and the essential oil exhibited high activity against methicillin-resistant Staphylococcus aureus (MRSA) with an inhibition zone of 23 mm. It also exhibited remarkable antifungal activity against Candida albicans with an inhibition zone of 26 mm.
Neuroprotective γ-Pyrones from Fusarium Solani JS-0169: Cell-Based Identification of Active Compounds and an Informatics Approach to Predict the Mechanism of Action (2020)

Glutamate toxicity has been implicated in neuronal cell death in both acute CNS injury and in chronic diseases. In our search for neuroprotective agents obtained from natural sources that inhibit glutamate toxicity, an endophytic fungus, <i>Fusarium solani</i> JS-0169 isolated from the leaves of <i>Morus alba</i>, was found to show potent inhibitory activity. Chemical investigation of the cultures of the fungus JS-0169 afforded isolation of six compounds, including one new γ-pyrone (1), a known γ-pyrone, fusarester D (2), and four known naphthoquinones: karuquinone B (3), javanicin (4), solaniol (5), and fusarubin (6). To identify the protective effects of the isolated compounds (1-6), we assessed their inhibitory effect against glutamate-induced cytotoxicity in HT22 cells. Among the isolates, compound 6 showed significant neuroprotective activity on glutamate-mediated HT22 cell death. In addition, the informatics approach using in silico systems pharmacology identified that compound 6 may exert its neuroprotective effect by controlling the amount of ubiquinone. The results suggest that the metabolites produced by the endophyte <i>Fusarium solani</i> JS-0169 might be related to the neuroprotective activity of its host plant, <i>M. alba</i>.
School-level determinants of incidence of sports-related concussion: Findings from the CARE Consortium (2023)

A large portion of the apparent variability between schools was attributable to structural factors (sport risk and competitive level), suggesting that there were minimal systemic differences in concussion identification between schools. While most variability is within-school, understanding school-level determinants of concussion risk may still be important in providing the implementation science context for individual-level interventions.
Effect of Sintering Atomospheres on the Sinterablity of Metal Injection Molded Compact. (1994)

of sintering atomospheres on the sinterability of injection molded compacts were investigated. The results obtained were as follows.
Seal Technology Development for Advanced Component for Airbreathing Engines (2008)

Key aspects of the design of sealing systems for On Rotor Combustion/Wave Rotor (ORC/WR) systems were addressed. ORC/WR systems generally fit within a broad class of pressure gain Constant Volume Combustors (CVCs) or Pulse Detonation Combustors (PDCs) which are currently being considered for use in many classes of turbine engines for dramatic efficiency improvement. Technology readiness level of this ORC/WR approaches are presently at 2.0. The results of detailed modeling of an ORC/WR system as applied to a regional jet engine application were shown to capture a high degree of pressure gain capabilities. The results of engine cycle analysis indicated the level of specific fuel consumption (SFC) benefits to be 17 percent. The potential losses in pressure gain due to leakage were found to be closely coupled to the wave processes at the rotor endpoints of the ORC/WR system. Extensive investigation into the sealing approaches is reported. Sensitivity studies show that SFC gains of 10 percent remain available even when pressure gain levels are highly penalized. This indicates ORC/WR systems to have a high degree of tolerance to rotor leakage effects but also emphasizes their importance. An engine demonstration of an ORC/WR system is seen as key to progressing the TRL of this technology. An industrial engine was judged to be a highly advantageous platform for demonstration of a first generation ORC/WR system. Prior to such a demonstration, the existing NASA pressure exchanger wave rotor rig was identified as an opportunity to apply both expanded analytical modeling capabilities developed within this program and to identify and fix identified leakage issues existing within this rig. Extensive leakage analysis of the rig was performed and a detailed design of additional sealing strategies for this rig was generated.
Role of antioxidant vitamins in prevention of cardiovascular diseases (1999)

Trust wants help in formulating system to recognise performance of salaried GPsEditor-General practitioners (academic and non-academic) are still excluded from the merit award arrangements for consultants.We are therefore asking readers to help us formulate a system to recognise progress and performance for salaried general practitioners in our trust.We currently employ several general practitioners on the NHS consultant salary scale.They take part in the discretionary points system, but we would like now to develop detailed proposals by which they could progress through enhanced payments-wholly funded by the trustagainst meritorious criteria, which would be widely recognised and acknowledged.This would give them similar opportunities for recognition to those
Phase‐sensitive inversion recovery for detecting myocardial infarction using gadolinium‐delayed hyperenhancement† (2002)

After administration of gadolinium, infarcted myocardium exhibits delayed hyperenhancement and can be imaged using an inversion recovery (IR) sequence. The performance of such a method when using magnitude-reconstructed images is highly sensitive to the inversion recovery time (TI) selected. Using phase-sensitive reconstruction, it is possible to use a nominal value of TI, eliminate several breath-holds otherwise needed to find the precise null time for normal myocardium, and achieve a consistent contrast. Phase-sensitive detection is used to remove the background phase while preserving the sign of the desired magnetization during IR. Experimental results are presented which demonstrate the benefits of both phase-sensitive IR image reconstruction and surface coil intensity normalization for detecting myocardial infarction (MI). The phase-sensitive reconstruction method reduces the variation in apparent infarct size that is observed in the magnitude images as TI is changed. Phase-sensitive detection also has the advantage of decreasing the sensitivity to changes in tissue T(1) with increasing delay from contrast agent injection.
Combat Motivation and the Roots of Fanaticism: The 12th SS Panzer Division in Normandy (2001)

The post-First World War dispute between Sir Sam Hughes, Minister of Militia and Defence from October 1911 to November 1916 and Sir Arthur Currie, General Officer Commanding the Canadian Corps from 9 June 1917 to the end of the war, must be one of the least dignified episodes in Canadian military history. Hughes, although very energetic, was also erratic and arbitrary and was fired by Prime Minister Sir Robert Borden for his inefficient administration of the Canadian military forces overseas. Currie, on the other hand, led the Canadian Corps in a stunning series of successes: Hill 70, Passchendaele, Amiens, the Drocourt-Queant Line, the Canal du Nord, and the final entry into the Belgian town of Mons on the last day of the war. He has, indeed, been viewed by historians as one of the warâs most capable field commanders and, arguably, as Canadaâs greatest native-born military commander.
2014 Colloidal Semicondut Nanycryst GRC (2014)

Final Conference Program & Registration List
Some considerations in the analysis of clinical DNA histogram data (1990)

In this brief paper, we will examine the theoretical basis of several cell cycle distribution analysis techniques that are frequently used for the analysis of clinical DNA histograms. The class of analysis technique that will be discussed is that which assumes a model that describes the DNA distribution and uses some sort of fitting procedure to adjust the parameters in the model so that the model agrees with the data as well as is possible. Several of the techniques described are included in commercially available DNA histogram analysis packages. 16 refs., 7 figs.
Input-to-state stability of infinite-dimensional systems: recent results\n and open questions (2019)

In a pedagogical but exhaustive manner, this survey reviews the main results\non input-to-state stability (ISS) for infinite-dimensional systems. This\nproperty allows estimating the impact of inputs and initial conditions on both\nthe intermediate values and the asymptotic bound on the solutions. ISS has\nunified the input-output and Lyapunov stability theories and is a crucial\nproperty in the stability theory of control systems as well as for many\napplications whose dynamics depend on parameters, unknown perturbations, or\nother inputs. In this paper, starting from classic results for nonlinear\nordinary differential equations, we motivate the study of ISS property for\ndistributed parameter systems. Then fundamental properties are given, as an ISS\nsuperposition theorem and characterizations of (global and local) ISS in terms\nof Lyapunov functions. We explain in detail the functional-analytic approach to\nISS theory of linear systems with unbounded input operators, with special\nattention devoted to ISS theory of boundary control systems. The Lyapunov\nmethod is shown to be very useful for both linear and nonlinear models,\nincluding parabolic and hyperbolic partial differential equations. Next, we\nshow the efficiency of the ISS framework to study the stability of large-scale\nnetworks, coupled either via the boundary or via the interior of the spatial\ndomain. ISS methodology allows reducing the stability analysis of complex\nnetworks, by considering the stability properties of its components and the\ninterconnection structure between the subsystems. An extra section is devoted\nto ISS theory of time-delay systems with the emphasis on techniques, which are\nparticularly suited for this class of systems. Finally, numerous applications\nare considered in this survey, where ISS properties play a crucial role in\ntheir study. This survey suggests many open problems throughout the paper.\n
Estudio de seis mutaciones en el gen gjb2 en pacientes cubanos con sorderas neurosensoriales no sindrómicas (2007)

La sordera es una perdida parcial o total de la audicion, que puede manifestarse a cualquier edad y con diferente grado de severidad. El 50% de las afectaciones de la audicion presentan un origen genetico, y entre ellas, las sorderas neurosensoriales no sindromicas representan el 70%. Las mas frecuentes son las de herencia autosomica recesiva, que constituyen mas del 80% de los casos. En Cuba, las sorderas autosomicas recesivas a nivel molecular no se han caracterizado suficientemente. El objetivo de este estudio fue determinar la frecuencia de seis mutaciones en el gen gjb2, en pacientes cubanos con sorderas neurosensoriales no sindromicas. Para la pesquisa de las mutaciones W24X, M34T, E47X, V95M, W77R y 35delG en este gen, se empleo la tecnica PCR-RFLP y la tecnica de heteroduplex. De las seis mutaciones, solamente cuatro se detectaron mediante la tecnica PCR-RFLP, y la 35delG (70%) y M34T (20%) resultaron mas frecuentes. Cada una de las otras dos mutaciones (W77R y E47X) represento el 5%. El analisis de heteroduplex resulto ser muy informativo al detectarse la formacion de siete heteroduplex en los fragmentos analizados, correspondientes a seis pacientes, y en un paciente se observo la formacion de heteroduplex en dos fragmentos amplificados. En dos de los pacientes, el heteroduplex complemento una mutacion anteriormente detectada por la tecnica PCR-RFLP. Se identificaron cinco familias en las que el diagnostico de los portadores de la sordera hereditaria autosomica recesiva llevo a definir el genotipo responsable de la enfermedad