gebhart/patrepeval huggingface dataset:
Experiencing the past in virtual reality: A virtual reality event for the French National Days of Archaeology (2013)

This document reports a public exhibition organized during the French National Days of Archaeology, that is the result of an interdisciplinary collaboration between archaeologists and computer scientists, centered on the immersive virtual reality platform Immersia, a node of the European Visionair project. This public exhibition had three main goals: (i) presentating our interdisciplinary collaboration, (ii) communicating on the scientific results of this collaboration, and (iii) offering an immersive experience in the past for visitors. This paper presents the scientific context of the event, its organization, and a discussion on feedbacks.
Reduced Nickel Concentration in a Stainless-Steel Deposit from Bias Sputtering (1970)

First Page
The VIP Gene Is a Dominant Modulator of the Pulmonary Circulation (2012)

Targeted deletion of the vasoactive intestinal peptide (VIP) gene results in a spontaneous PAH phenotype, with vascular remodeling, right ventricular hypertrophy, and inflammation in normoxic mice (1). Treatment with VIP (15 μg, s.c., q.o.d, for 4 wk) reverses the PAH pathology (1).

To explore the full genomic effects of VIP gene deletion, we examined the lungs of VIP−/− mice by gene microarray analysis and quantitative RT PCR. There were extensive gene expression abnormalities (2). Up-regulated genes were those promoting vasoconstriction, vascular smooth muscle cell migration and proliferation, and collagen deposition, including: angiopoietin, 5 HT receptor 3A, endothelin receptor A, and platelet-derived growth factor β and its receptor polypeptides, as well as genes of several inflammatory cytokines and chemokines often linked to vascular remodeling, including the TNF receptor superfamily, C-C motif chemokine receptors, mast celprotease 8, and nuclear factor of activated T cells (NFAT)c2. Conversely, genes promoting vasodilatation and defense against pulmonary vascular remodeling, were down-regulated, including: β2-adrenergic receptor, GTP cyclohydrolase 1, the rate-limiting enzyme in the biosynthesis of tetrahydrobiopterin, an essential co-factor for endothelial NO synthase (NOS3) activity, NOS3 itself, adrenomedullin receptor, prostacyclin synthase, BMP2 and BMPR2, apolipoprotein E, and KV channels.

As a follow-up, we recently examined the effect of VIP treatment on these gene expression abnormalities (n=5). Compared with a control VIP−/− group, major alterations outlined above were largely corrected (unpublished observations).

We conclude that (1) absence of the VIP gene results in altered expression of multiple other genes involved in the genesis of PAH; (2) like the VIP−/− phenotype, the genetic alterations were reversible with VIP treatment, suggesting a causal relationship; (3) VIP exerts a powerful modulator influence on genes and pathways controlling the structure and function of the mouse pulmonary circulation; and (4) VIP may have a similar modulator role in the human pulmonary circulation.
Geometrical characteristics of eggs from 3 poultry species (2020)

We studied the correlations between egg geometrical parameters (i.e., egg shape index, sphericity, geometric mean diameter, surface area, and volume) and eggshell qualities, or the organic matrix in eggshell. Eggs were collected from 5 poultry breeds belonging to 3 species (commercial Hy-line Brown Chicken, Shaoxing Duck, Jinding Duck, Taihu Goose, and Zhedong White Goose). The geometrical parameters showed high variation among 3 species of poultry, and even between breeds in the same species. The five geometrical parameters were grouped into 2 sets, one contained shape index and sphericity, the other comprised geometric mean diameter, surface area, and volume. The parameters in the same set can be perfectly fitted to one another. Egg weight, shell membrane weight, and calcified shell weight were significantly correlated with geometric mean diameter, surface area, and volume. In accordance with false discovery rate-adjusted P value, both shell membrane relative weight and calcified shell thickness showed no significant correlations with any of the geometrical parameters. However, the correlations between geometrical parameters and other shell variables (calcified shell weight, shell relative weight, calcified shell thickness uniformity, and eggshell breaking strength) depend on breed. Both constitutive proportions and percentage contents of 3 eggshell matrix components (acid-insoluble, water-insoluble, and both acid and water facultative-soluble matrix) had no effects on egg shape and size. The correlations between the amounts of various shell matrix, egg shape and size depend on breed or species. This study provides a methodology and the correlation between geometrical parameters and eggshell qualities, and between geometrical parameters and organic matrix components in calcified shells.
Glass-physics (2015)

We demonstrate how Smart Glasses can support high school science experiments. The vision is to (1) reduce the "technical" effort involved in conducting the experiments (measuring, generating plots etc.) and to (2) allow the students to interactively see/manipulate the theoretical representation of the relevant phenomena while at the same time interacting with them in the real world. As a use case, we have implemented a Google Glass app for a standard high school acoustics school experiment (determining the relationship between tone frequency that hitting a glass filled with water generates and the amount of water in the glass). We evaluated the system with a group of 36 high grade students split into a group using our application and a control group using an existing tablet based system. We show a statistically significant advantage in experiment execution speed, cognitive load, and curiosity.
Dexterous manipulation in multi-degree-of-freedom based on modal-space disturbance compensation (2009)

This paper defines ¿modal space disturbance¿, which is the position error of between environment in real world and virtual system in modal space. The virtual system motions are abstracted by using mode quarry matrix. In addition, this paper proposes ¿modal space disturbance observer¿ which estimates modal space disturbance. An estimate value of modal space disturbance is calculated, it becomes possible to compensate modal space disturbance. Moreover, when propose method is used, it is possible to compensate the position error of between unknown system and environment without calculating complicated arrangement of system. The experimental results show the viability of the proposed method.
15kV/40A FREEDM super-cascode: A cost effective SiC high voltage and high frequency power switch (2016)

High voltage wide bandgap (WBG) semiconductor devices like the 15kV SiC MOSFET have attracted great attentions because of its potential applications in high voltage and high frequency power converters. However, these devices are not commercially available at the moment and their high cost due to expensive material growth and fabrication may limit their widespread adoption in the future. In this paper, a 15kV/40A three terminal power switch, the FREEDM Super-Cascode, is reported for the first time which is based on series connection of 1.2kV SiC power devices. The design and operation principle of the FREEDM Super-Cascode are introduced and the performance including the static blocking capability, conduction characteristics over a wide range of temperatures, and dynamic switching performances are analyzed. In addition, the thermal resistance of the FREEDM Super-Cascode is measured and the power dissipation capability is projected. The FREEDM Super-Cascode costs only one third of the estimated high voltage SiC MOSFETs, and will facilitate early applications of SiC in very high voltage and high frequency power converters.
Péptidos antimicrobianos: Estructura, función y aplicaciones (2017)

Los péptidos antimicrobianos recientemente descubiertos corresponden a una primera línea de defensa contra los patógenos. Se han descrito provenientes de bacterias, insectos, plantas y vertebrados, y se conocen varios grupos de péptidos antimicrobianos dependiendo de su estructura: alfa-helicoidales, de estructura extendida y de composición irregular, para los que se han propuesto varios modelos de interacción con las membranas de las bacterias, pero, en general, los péptidos causan poros líticos. En la mayoría de los casos estos péptidos son sintetizados ribosomalmente, algunos como preproteínas. Se ha propuesto una serie de aplicaciones para el control de infecciones bacterias, especialmente aquellas localizadas en la piel o en las mucosas. Se han desarrollado plantas transgénicas que expresan péptidos antimicrobianos y se ha logrado reducir la incidencia de enfermedades.
Mechanism of nanoparticle manipulation by scanning tunnelling microscopy (2006)

Scanning tunnelling microscopy (STM) imaging was performed on gold surfaces with a large coverage of monodispersed silver nanoparticles soft-landed on the surface from the gas phase. In both ambient and ultra-high vacuum conditions, STM scanning was found to displace the particles out of the scanning area, due to weak adhesion of the particles to the substrate surface. Calculations based on contact mechanics and electrostatics show that the particles can overcome the force of adhesion to the surface and jump onto the STM tip beyond the tunnelling distance. The observation provides the possibility for patterning or arranging nanoparticles on a surface, which is demonstrated, and offers the potential for a multiplexed approach to create very precise surface patterns and particle arrangements.
Heteroaromatic analogs of the .alpha.2-adrenoreceptor partial agonist clonidine (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHeteroaromatic analogs of the .alpha.2-adrenoreceptor partial agonist clonidineChristopher B. Chapleo, Richard C. M. Butler, David C. England, Peter L. Myers, Alan G. Roach, Colin F. C. Smith, Michael R. Stillings, and Ian F. TullochCite this: J. Med. Chem. 1989, 32, 7, 1627–1630Publication Date (Print):July 1, 1989Publication History Published online1 May 2002Published inissue 1 July 1989https://pubs.acs.org/doi/10.1021/jm00127a037https://doi.org/10.1021/jm00127a037research-articleACS PublicationsRequest reuse permissionsArticle Views333Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Cost-effective mass fabrication of multilevel diffractive optical elements by use of a single optical exposure with a gray-scale mask on high-energy beam-sensitive glass (1997)

We present a method for reproducing diffractive optical elements in quantity. The method is compatible with VLSI microfabrication techniques and involves generating a gray-scale mask. The gray-scale mask is employed in an optical aligner to expose an analog photoresist on any environmentally durable substrate, e.g., glass, quartz, semiconductor, or metal, one exposure for each diffractive optical element. After copies of the mask on the photoresist are developed, many substrates can be processed in parallel in a chemically assisted ion-beam etcher to transfer the microstructures on the analog resists simultaneously onto the surfaces of the substrates.
Physiological/Non-physiological artifacts classification using EEG signals based on CNN (2022)

Electroencephalographic signals have been shown to be extremely susceptible to noise from both external and internal sources. In this way, electroencephalography (EEG) can be considered a tool for analyzing the electrical activity of the brain. In the literature, there are numerous methods for detecting artifacts in EEG signals. Nevertheless, these approaches not attain a high level of accuracy in artifact detection. New techniques are needed to increase the accuracy level. Predictive Preventive and Personalized Medicine (PPPM) is becoming the focus of healthcare initiatives to guarantee the early identification of various types of artifacts. In this research, a binary classification is developed as physiological and non-physiological artifact detection. Various techniques are targeted for artifact classification as deep learning (DL) which is the most efficient strategy used for image and signals classification. Based on the convolutional neural network (CNN) model, we have classified the various artifact types. The Nihon Kohden device was used to acquire the available EEG data, which is collected from 32 channels. Our approach is validated with a CNN architecture for binary artifact classification. With a maximum accuracy of 99.55%, the proposed methodology delivers powerful classification findings.
DESARROLLO HUMANO Y RELACIONES DE PAREJA EN ESTUDIANTES DE LA UNIVERSIDAD DE PAMPLONA (2013)

Esta investigacion es un trabajo que aporta al desarrollo humano, desde el analisis de las relaciones de pareja de los estudiantes de la Universidad de Pamplona, describiendo el pasado, presente y futuro de las relaciones de estudiantes universitarios, la estructura de dicha relacion, sus cambios evolutivos, la satisfaccion en pareja, el proyecto de vida y rendimiento academico desde las percepciones mismas de los participantes, mediante tecnicas mixtas de investigacion desde una mirada sistemica, que permita comprender el desarrollo integral desde lo afectivo emocional como instrumento de cambio y transformacion hacia el Desarrollo Humano.
Polymere Reagenzien, 5. Polymere Selenreagenzien (1976)

Abstract Polymere Selenreagenzien vermeiden die Schwierigkeiten, die bei der Handhabung von niedermolekularen Selenverbindungen durch Geruchsbelästigung und Toxizität vorhanden sind. Die Synthese von polymeren Reagenzien mit Selenophenol‐ und Diphenylselenoxidgruppen wird beschrieben. Die Darstellung erfolgt einmal ausgehend von vernetztem Polystyrol durch polymeranaloge Umsetzung, zum anderen durch Copolymerisation von selenhaltigen Monomeren mit Divinylbenzol. Die Reaktionen der polymeren Selenreagenzien werden an einigen Beispielen exemplarisch belegt.
Comparison of Rat and Human Responses to Toll-Like Receptor 7 Activation (2008)

Toll-like receptors recognize invading microorganisms and activate innate immune responses. Their discovery has opened up a range of therapeutic possibilities, in particular for infectious diseases. Responses to TLR agonists have been largely studied in mice and little information exists in other species. Given that rats are commonly used for pharmacokinetic and toxicology studies in drug development, we compared TLR7 responses in rat and human. Stimulation of rat and human peripheral blood mononuclear cells with the TLR7 agonist SM360320 showed that in rat cells, the interferon-induced gene, 2', 5' oligoadenylate synthase and tumor necrosis factor alpha were induced at lower concentrations and to a greater degree compared with human cells. Both human and rat cells demonstrated tolerance and could not be restimulated following initial treatment with high concentrations of SM360320. Reducing the concentration of the initial treatment allowed cells to be restimulated following a period of recovery. The initial treatment concentration had to be reduced to a greater extent to enable restimulation of rat cells compared with human cells. Dosing whole rats repeatedly with different concentrations of SM360320 confirmed the in vitro results. Treatment of human cells with high concentrations of interferon alpha did not induce tolerance to subsequent treatment with SM360320 indicating that tolerance occurs in the TLR7 signaling pathway, rather than the interferon signaling pathway. We conclude that rat and human cells respond differently to TLR7 activation and that these differences should be considered when using rat as a model to study TLR7 agonists.
A novel composite material specifically developed for ultrasound bone phantoms: cortical, trabecular and skull (2013)

In the various stages of developing diagnostic and therapeutic equipment, the use of phantoms can play a very important role in improving the process, help in implementation, testing and calibrations. Phantoms are especially useful in developing new applications and training new doctors in medical schools. However, devices that use different physical factors, such as MRI, Ultrasound, CT Scan, etc will require the phantom to be made of different physical properties. In this paper we introduce the properties of recently designed new materials for developing phantoms for ultrasonic human body investigation, which in today's market make up more than 30% in the world of phantoms. We developed a novel composite material which allows fabrication of various kinds of ultrasound bone phantoms to mimic most of the acoustical properties of human bones. In contrast to the ex vivo tissues, the proposed material can maintain the physical and acoustical properties unchanged for long periods of time; moreover, these properties can be custom designed and created to suit specific needs. As a result, we introduce three examples of ultrasound phantoms that we manufactured in our laboratory: cortical, trabecular and skull bone phantoms. The paper also presents the results of a comparison study between the acoustical and physical properties of actual human bones (reported in the referenced literatures) and the phantoms manufactured by us.
Effects of Fuel Loading on Potential Fire Behavior and Soil Erosion in Coast Redwood Stands (2006)

Commercial timber harvesting typically reduces aerial fuel loading and continuity, but can actually heighten fire activity through increased surface fuel loading (Agee 1997). Fuel depth and loading, which typically increase after harvest, play a significant role in fire intensity and rate of spread in redwood forests (Sequoia sempervirens) (D. Don.) Endl.) (Nives 1989), which are significant predictors of redwood mortality (Finney and Martin 1993). However, residual slash fuels may simultaneously reduce erosion, which may be of greater importance in some areas because they intercept rainfall and soil particles dispersed by overland flow (Fernandez et al. 2004). The relationship of surface fuel loading on potential fire behavior and soil erosion was explored in coast redwood stands that were selectively harvested 11 years prior to this study by either cable- or tractor-skidding methods (Piirto et al. 1997). The objectives of this study were to (1) assess fuel loading and potential fire behavior in harvested stands and (2) determine if surface soil erosion was influenced by surface fuels.
Modulation strategies for direct-link drive for open-end winding AC machines (2009)

Switching common-mode voltages generated by conventional pulse-width modulated inverters are known to cause bearing currents in ac machines. These undesirable currents may result in bearing damage. A direct-link drive for open-end winding ac machines has recently been proposed. Some advantages of the drive include: 1) common-mode voltage suppression, 2) no storage elements, and 3) ability to achieve up to 1.5 times the peak input phase voltage across the machine phase windings. In this paper, pulsewidth modulation strategies for the drive are proposed. Two strategies are based on space vector modulation and suppress common-mode voltage at the machine terminals. One carrier-based strategy achieves 1.5 times the peak input phase voltage across the machine phase windings but causes switching common-mode voltage at the machine terminals. Simulation and experimental results are presented to verify the operation of the drive.
Evidence for a restricted idiotypic and epitopic specificity of anti‐thyroglobulin autoantibodies in patients with autoimmune thyroiditis (1991)

Anti-thyroglobulin (TG) autoantibodies from patients with autoimmune thyroiditis express a cross-reactive alpha idiotype (Id) termed T44 which is not expressed by IgG from normal individuals. The present study demonstrates that the expression of the T44 Id is strongly associated with the recognition by anti-TG autoantibodies of a specific epitopic cluster on human TG. The epitopic reactivity of anti-TG autoantibodies was determined using a competitive inhibition assay with a panel of 15 monoclonal antibodies that define six antigenic clusters on TG. All T44+ autoantibodies from patients recognized cluster II, whereas no anti-TG IgG from healthy individuals reacted with this region. Affinity columns of Sepharose-bound intravenous therapeutic immunoglobulins which contain anti-T44 activity, retained both T44 Id-expressing antibodies and a subset of region II-specific anti-TG autoantibodies from patients with Hashimoto's disease. Restricted idiotypic and epitopic specificity may demarcate disease-associated from natural anti-TG autoantibodies, suggesting that qualitative rather than quantitative criteria should be used to identify pathological autoantibodies.
Associations of Dairy Consumption and Cognitive Function in the Boston Puerto Rican Health Study (2022)

To examine the cross-sectional and prospective associations between dairy consumption and cognitive function among Puerto Rican adults. Data are from the Boston Puerto Rican Health Study (57 yrs, 71% female), an ongoing prospective cohort study. Diet was assessed using a validated food frequency questionnaire. Dairy products included milk, cheese, yogurt, cream, and butter. Our dairy exposures were total dairy (s/d), regular & reduced fat dairy (s/d), and nonfat dairy products (s/d). A battery of neurocognitive tests was administered by trained staff in the language of preference. Global cognitive function score (GCS) was calculated as the mean z-scores of the individual tests. A subset of BPRHS participants returned for neurocognitive testing at 13-yr follow-up. For the current study, we examined the baseline cross-sectional associations between dairy and GCS (n = 1067) and the prospective associations of dairy consumption (averaged of baseline and 2-yr FFQ data) with GCS at 13 years (n = 433). Multivariable linear regression models were adjusted for age, sex, education, smoking, physical activity, energy intake, and consumption of fruits and vegetables and added sugar. Baseline GCS was additionally included in prospective models. Dairy variables were skewed, and a log-transformation was applied. Average dairy consumption for total, regular & reduced fat dairy, and nonfat dairy was 2.2 s/d, 1.9, s/d, and 0.3 s/d, respectively. In cross-sectional analyses, total [β = 0.078 (0.033, 0.124), P = 0.001] and reduced & regular fat dairy [0.066 (0.020, 0.112), P = 0.005] were positively associated with GCS. Nonfat dairy was not significantly associated [0.015 (−0.001, 0.033), P = 0.210]. In prospective analyses, we observed null associations between total [−0.0134 (−0.094, 0.067), P = 0.740], regular & reduced-fat [−0.039 (−0.123, 0.046), P = 0.370], and nonfat dairy [0.0027 (−0.020, 0.026), P = 0.820] and 13-yr GCS. In this cohort of Puerto Rican adults, total and regular & reduced-fat dairy was associated with greater global cognitive function in cross-sectional analyses at baseline, but not after 13 years of follow-up. Additional prospective analyses are warranted to clarify these associations. National Institute on Aging.