gebhart/patrepeval huggingface dataset:
Measured-based equivalent RC circuits for simulating the frequency behavior of MWCNT/epoxy nanocomposites (2012)

The first results of a research aimed at developing equivalent electric circuits for the simulation of the electromagnetic responses of epoxy-based nanocomposites obtained with different percentages of MWCNTs are presented. Simple series and parallel RC cells are considered to simulate the impedance frequency dependence over a range of MWCNT concentrations encompassing the percolation threshold of the nanocomposite system. The RC electric circuits are constructed by employing a simple multi-step procedure in which the values of the parameters are adjusted until a suitable criterion based on the comparison of simulated and experimental frequency spectra is satisfied. It is found that a few cells are enough to obtain a satisfactory agreement between experimental results and numerical simulations.
Deletion of Kvβ1.1 subunit leads to electrical and haemodynamic changes causing cardiac hypertrophy in female murine hearts (2016)

What is the central question of this study? The goal of this study was to evaluate sex differences and the role of the potassium channel β1 (Kvβ1) subunit in the heart. What is the main finding and its importance? Genetic ablation of Kvβ1.1 in females led to cardiac hypertrophy characterized by increased heart size, prolonged monophasic action potentials, elevated blood pressure and increased myosin heavy chain α (MHCα) expression. In contrast, male mice showed only electrical changes. Kvβ1.1 binds the MHCα isoform at the protein level, and small interfering RNA targeted knockdown of Kvβ1.1 upregulated MHCα. Cardiovascular disease is the leading cause of death and debility in women in the USA, and cardiac arrhythmias are a major concern. Voltage-gated potassium (Kv) channels along with the binding partners; Kvβ subunits are major regulators of the action potential (AP) shape and duration (APD). The regulation of Kv channels by the Kvβ1 subunit is unknown in female hearts. In the present study, we hypothesized that the Kvβ1 subunit is an important regulator of female cardiac physiology. To test this hypothesis, we ablated (knocked out; KO) the KCNAB1 isoform 1 (Kvβ1.1) subunit in mice and evaluated cardiac function and electrical activity by using ECG, monophasic action potential recordings and echocardiography. Our results showed that the female Kvβ1.1 KO mice developed cardiac hypertrophy, and the hearts were structurally different, with enlargement and increased area. The electrical derangements caused by Kvβ1.1 KO in female mice included long QTc and QRS intervals along with increased APD (APD20-90% repolarization). The male Kvβ1.1 KO mice did not develop cardiac hypertrophy, but they showed long QTc and prolonged APD. Molecular analysis showed that several genes that support cardiac hypertrophy were significantly altered in Kvβ1.1 KO female hearts. In particular, myosin heavy chain α expression was significantly elevated in Kvβ1.1 KO mouse heart. Using a small interfering RNA strategy, we identified that knockdown of Kvβ1 increases myosin heavy chain α expression in H9C2 cells. Collectively, changes in molecular and cell signalling pathways clearly point towards a distinct electrical and structural remodelling consistent with cardiac hypertrophy in the Kvβ1.1 KO female mice.
Opioid receptors of bovine posterior pituitary neurosecretosomes are exclusively kappa. (1986)

Intact neurosecretosomes (NSS) from bovine posterior pituitary were prepared and characterized. Ligand binding studies were performed, using 3H-[D-Ala2-D-Leu5]enkephalin (DADL), 3H-etorphine and 3H-ethylketocyclazocine (EKC). The absence of specific binding of 3H-DADL and the inability of DADL to displace 3H-etorphine, implies the absence of mu, delta, or DADL-suppressible benzomorphan ("kappa-2") sites. Self- and cross displacement studies for etorphine and EKC suggested receptor heterogeneity. EKC fails to displace - 20% of specific binding of etorphine. Mathematical modelling indicates the presence of three classes of sites. The present findings imply that bovine posterior pituitary opioid receptors are exclusively of the kappa type.
Cancer control and functional outcomes after radical prostatectomy as markers of surgical quality: analysis of heterogeneity between surgeons at a single cancer center (2011)

Background: Previous studies have shown that complications and biochemical recurrence rates after radical prostatectomy (RP) vary between different surgeons to a greater extent than might be expected by chance. Data on urinary and erectile outcomes, however, are lacking. Objective: In this study, we examined whether between-surgeon variation, known as heterogeneity, exists for urinary and erectile outcomes after RP. Design, Setting, and Participants: Our study consisted of 1910 RP patients who were treated by 1 of 11 surgeons between January 1999 and July 2007. Intervention: All patients underwent RP at Memorial Sloan-Kettering Cancer Center. Measurements: Patients were evaluated for functional outcome 1 yr after surgery. Multivariable random effects models were used to evaluate the heterogeneity in erectile or urinary outcome between surgeons, after adjustment for case mix (age, prostate-specific antigen, pathologic stage and grade, comorbidities) and year of surgery. Results and Limitations: We found significant heterogeneity in functional outcomes after RP (p < 0.001 for both urinary and erectile function). Four surgeons had adjusted rates of full continence < 75%, whereas three had rates > 85%. For erectile function, two surgeons in our series had adjusted rates < 20%; another two had rates > 45%. We found some evidence suggesting that surgeons' erectile and urinary outcomes were correlated. Contrary to the hypothesis that surgeons "trade off" functional outcomes and cancer control, better rates of functional preservation were associated with lower biochemical recurrence rates. Conclusions: A patient's likelihood of recovering erectile and urinary function may differ depending on which of two surgeons performs his RP. Functional preservation does not appear to come at the expense of cancer control; rather, both are related to surgical quality.
Towards automated provisioning of secure virtualized networks (2007)

We describe a secure network virtualization framework that helps realize the abstraction of Trusted Virtual Domains (TVDs), a security-enhanced variant of virtualized network zones. The framework allows groups of related virtual machines running on separate physical machines to be connected together as though there were on their own separate network fabric and, at the same time, helps enforce cross-group security requirements such as isolation, confidentiality, security, and information flow control. The framework uses existing network virtualization technologies, such as Ethernet encapsulation, VLAN tagging, and VPNs, and combines and orchestrates them appropriately to implement TVDs. Our framework aims at automating the instantiation and deployment of the appropriate security mechanism and network virtualization technologies based on an input security model that specifies the required level of isolation and permitted network flows. We have implemented a prototype of the framework based on the Xen hypervisor. Experimental evaluation of the prototype shows that the performance of our virtual networking extensions is comparable to that of the standard Xen configuration.
Patellofemoral arthroplasty influences tibiofemoral kinematics: the effect of patellar thickness (2014)

Isolated patellofemoral arthroplasty alters natural tibiofemoral kinematics, and the effects become more pronounced in case of increased patellar thickness. Therefore, it might be recommended to aim for a slight over-resection of patellar bone if sufficient bone stock is available.
Replication factors required for SV40 DNA replication in vitro. II. Switching of DNA polymerase alpha and delta during initiation of leading and lagging strand synthesis (1991)

Replication factors A and C (RF-A and RF-C) and the proliferating cell nuclear antigen (PCNA) differentially augment the activities of DNA polymerases alpha and delta. The mechanism of stimulation by these replication factors was investigated using a limiting concentration of primed, single-stranded template DNA. RF-A stimulated polymerase alpha activity in a concentration-dependent manner, but also suppressed nonspecific initiation of DNA synthesis by both polymerases alpha and delta. The primer recognition complex, RF-C.PCNA.ATP, stimulated pol delta activity in cooperation with RF-A, but also functioned to prevent abnormal initiation of DNA synthesis by polymerase alpha. Reconstitution of DNA replication with purified factors and a plasmid containing the SV40 origin sequences directly demonstrated DNA polymerase alpha dependent synthesis of lagging strands and DNA polymerase delta/PCNA/RF-C dependent synthesis of leading strands. RF-A and the primer recognition complex both affected the relative levels of leading and lagging strands. These results, in addition to results in an accompanying paper (Tsurimoto, T., and Stillman, B. (1991) J. Biol. Chem. 266, 1950-1960), suggest that an exchange of DNA polymerase complexes occurs during initiation of bidirectional DNA replication at the SV40 origin.
Glidar: An OpenGL-based, Real-Time, and Open Source 3D Sensor Simulator for Testing Computer Vision Algorithms (2016)

3D sensors such as lidars, stereo cameras, time-of-flight cameras, and the Microsoft Kinect are increasingly found in a wide range of applications, including gaming, personal robotics, and space exploration. In some cases, pattern recognition algorithms for processing depth images can be tested using actual sensors observing real-world objects. In many situations, however, it is common to test new algorithms using computer-generated synthetic images, as such simulations tend to be faster, more flexible, and less expensive than hardware tests. Computer generation of images is especially useful for Monte Carlo-type analyses or for situations where obtaining real sensor data for preliminary testing is difficult (e.g., space applications). We present Glidar, an OpenGL and GL Shading Language-based sensor simulator, capable of imaging nearly any static three-dimensional model. Glidar allows basic object manipulations, or may be connected to a physics simulator for more advanced behaviors. It permits publishing to a tcp socket at high frame-rates or can save to pcd (point cloud data) files. The software is written in C++, and is released under the open source bsd license.
Field Attraction of Scolytus scolytus (F.) to the Enantiomers of 4-Methyl-3-heptanol, the Major Component of the Aggregation Pheromone (1979)

The attraction of Scolytus scolytus (F.) to the four enantiomers of 4-methyl-3-heptanol, the major component of the aggregation pheromone, was studied in the field. Only the (–)–threo isomer attracted significantly more beetles than the blank (control), and the response to this isomer was not significantly different from the response to commercial 4-methyl-3-heptanol, which contains all four isomers. There was no evidence for inhibition of attraction by the other three isomers. Commercial 4-methyl-3-heptanol could therefore be used, in combination with other components of the aggregation pheromone, for population sampling and control by mass trapping of S. scolytus .
Tacticity Control in the Synthesis of Poly(lactic acid) Polymer Stars with Dipentaerythritol Cores (2010)

The synthesis of a family of polymer stars with arms of varied tacticities is discussed. The effect of polymer tacticity on the physical properties of these polymer stars is presented. Dipentaerythritol cores support six poly(lactic acid) (PLA) arms. Lewis acidic tin and aluminum catalysts control the polymerization to afford polymer stars of variable tacticity. The analysis of these polymers by NMR spectroscopy, thermogravimetric analysis, powder X-ray diffraction, and differential scanning calorimetry reveals the effects of tacticity control on the physical properties of the polymer stars. Preliminary decomposition studies suggest that the biodegradation profile of a polymer star may also be tuned by stereochemical control. This is the first systematic altering of tacticity in PLA polymer stars, showing that polymer tacticity can have a great impact on star properties.
MixedFusion: Real-Time Reconstruction of an Indoor Scene with Dynamic Objects (2017)

Real-time indoor scene reconstruction aims to recover the 3D geometry of an indoor scene in real time with a sensor scanning the scene. Previous works of this topic consider pure static scenes, but in this paper, we focus on more challenging cases that the scene contains dynamic objects, for example, moving people and floating curtains, which are quite common in reality and thus are eagerly required to be handled. We develop an end-to-end system using a depth sensor to scan a scene on the fly. By proposing a Sigmoid-based Iterative Closest Point (S-ICP) method, we decouple the camera motion and the scene motion from the input sequence and segment the scene into static and dynamic parts accordingly. The static part is used to estimate the camera rigid motion, while for the dynamic part, graph node-based motion representation and model-to-depth fitting are applied to reconstruct the scene motions. With the camera and scene motions reconstructed, we further propose a novel mixed voxel allocation scheme to handle static and dynamic scene parts with different mechanisms, which helps to gradually fuse a large scene with both static and dynamic objects. Experiments show that our technique successfully fuses the geometry of both the static and dynamic objects in a scene in real time, which extends the usage of the current techniques for indoor scene reconstruction.
Auswahlstrategie von Kooperationspartnern im Kontext der Produktpiraterie (2009)

Kurzfassung Auf Grund der zunehmenden Globalisierung sind Unternehmen der Investitionsgüterindustrie stark miteinander vernetzt und in Folge von ungewolltem Know-how-Abfluss im vermehrten Maße von Produktpiraterie betroffen. Zusätzlich führt der steigende internationale Wettbewerb dazu, dass sich die Unternehmen auf ihre Kernkompetenzen konzentrieren und durch Outsourcing den Anteil an Zukaufteilen erhöhen. Aus diesem Grund stellt die Bewertung und Auswahl geeigneter Kooperationspartner eine besondere Herausforderung dar. Im vorliegenden Beitrag wird eine Methode vorgestellt, die eine systematische Herangehensweise an das Thema Lieferantenauswahl und Unternehmenskooperationen, unter Berücksichtigung der Gefährdung durch Produktpiraterie, liefert.
Brain-derived proteins in the CSF, do they correlate with brain pathology in CJD? (2006)

Our results indicate that the alteration of levels of brain-derived proteins in the CSF does not only reflect the degree of neuronal damage, but it is also modified by the localization on the brain pathology. Brain specific lesion patterns have to be considered when analyzing CSF neuronal proteins.
Lymph Node Metastases Detection Using Gd2O3@PCD as Novel Multifunctional Contrast Imaging Agent in Metabolic Magnetic Resonance Molecular Imaging (2022)

Axillary lymph node detection is crucial to staging and prognosis of the lymph node metastatic spread in breast cancer. Currently, lymphoscintigraphy and blue dye, as the conventional methods to localize sentinel lymph nodes (SLNs), are invasive and can only be performed during surgery. This study has had a novel hybrid gadolinium oxide nanoparticle coating with Cyclodextrin-based polyester as a high-relaxivity T<sub>1</sub> magnetic resonance molecular imaging (MRMI) contrast agent (CA). Twelve female BALB/c mice were randomly divided into three groups of four mice; each group was injected with 4T<sub>1</sub> cells to obtain metastasis lymph nodes and diagnosed by using the 3D T<sub>1</sub>W (VIBE) MRI (Siemens 3T, Prisma). The synthesized Gd<sub>2</sub>O<sub>3</sub>@PCD nanoparticles with a suitable particle size range of 20-40 nm have had much higher longitudinal relaxivity (<i>r</i> <sub>1</sub>) for Gd<sub>2</sub>O<sub>3</sub>@PCD and Gd-DOTA (Dotarem) with the values of 3.98 mM<sup>-1</sup>·s<sup>-1</sup> ± 0.003 and 2.71 mM<sup>-1</sup>·s<sup>-1</sup> ± 0.005, respectively. Identical MR images in coronal views were subsequently obtained to create time-intensity curves of the right axillary lymph nodes and to measure the contrast ratio (CR). The peak CR and qualitative assessment of axillary lymph nodes at five-time points were evaluated. After subcutaneous injection, the contrast ratio of axillary lymph node and tumor in mice exhibited CR peak of Gd<sub>2</sub>O<sub>3</sub>@PCD and Dotarem with the values of 2.21 ± 0.06 and 0.40 ± 0.004 for lymph node and 2.54 ± 0.04 and 1.21 ± 0.007 for the tumor, respectively. Furthermore, the lumbar-aortic lymph node is weakly visible in the original coronal image. In conclusion, the use of Gd<sub>2</sub>O<sub>3</sub>@PCD nanoparticles as novel MRMI CAs enables high resolution for the detection of lymph node metastasis in mice with the potential capability for breast cancer diagnostic imaging.
Combining Three Different Types of Local Features for Generic Object Recognition (2007)

Japan いる [9]. 現在一般物体認識の分野では,画像中の物体の複数 の部分領域から抽出される局所特徴を用いる手法が注 目され広く研究されている.これまで一般物体認識に 使用されてきた局所特徴は,局所特徴が記述する領域 の違いに基づくと以下の 3種類に大別できる. タイプ 1 特徴的なテクスチャに着目 タイプ 2 画像領域の一様性に着目 タイプ 3 エッジ情報に着目 また,局所特徴を画像から抽出する手法は,抽出する 部分を特定する “検出” と,検出された領域の “アピ アランスの記述”に分かれ,各タイプ別にそれぞれ異 なる手法が用いられている.表 1 は,各タイプの手法 の一例を,局所特徴の検出とアピアランスの記述別に 分類したものである.なお本論文では,検出とアピア ランスの記述を合わせた処理を,局所特徴の抽出,と 呼ぶことにする.タイプ 1は,テクスチャが特徴的な (輝度変化が急で,一様でない)領域に着目する局所特 徴である.DoGやHarris-Affine detectorなどの手法 でこのような領域を検出し,SIFT記述子やDCTなど でその領域のテクスチャパターンを記述する.タイプ 1の局所特徴を使用している研究を挙げる. [10]では, 検出に Harris-Affine detectorが,記述に SIFT記述 子が使用されている. [11], [12] では,検出に Kadir
Image Processing for Interferometric Mie and Rayleigh Scattering Velocity Measurements (1999)

An image processing method has been developed, in conjunction with a Fabry-Perot interferometer, for the measurement of time-resolved local velocity of gas flows. The processing technique is used in order to determine, on-line, the Doppler shift in Mie or Rayleigh scattered light form the measurement volume. The method minimizes the adverse effects due to the drifting of laser frequency and interferometer alignment. The scattered light is mixed with unshifted light from the interrogation laser for reference before passing it through the interferometer. The concentric, double-ring pattern images formed at the output of the interferometer are captured by a CCD camera and analyzed for free spectral range and Doppler shift. The original images in polar coordinates are first mapped into a rectangular coordinate system and subsequently analyzed using an auto-correlat ion method in order to determine the Doppler frequency. Measurements were made in the near field of a slightly underexpanded Mach 1.6 supersonic jet. The results obtained by the present image analysis technique compare favorably with those obtained using a direct analysis method.
A long transcript mutant of the rubisco activase gene RCA upregulated by the transcription factor Ghd2 enhances drought tolerance in rice (2022)

The transcription factor Ghd2 increases rice yield potential under normal conditions and accelerates leaf senescence under drought stress. However, its mechanism on the regulation of leaf senescence under drought stress remains unclear. In the present study, to unveil the mechanism, one target of Ghd2, the Rubisco activase gene RCA, was identified through the combined analysis of Ghd2-CRISPR transcriptome data and Ghd2-overexpression microarray data. Ghd2 binds to the 'CACA' motif in the RCA promoter by its CCT domain and upregulates RCA expression. RCA has alternative transcripts, RCAS and RCAL, which are predominantly expressed under normal conditions and drought stress, respectively. Similar to Ghd2-overexpressing plants, RCAL-overexpressing plants were more sensitive to drought stress than the wild-type. However, the plants overexpressing RCAS showed a weak drought-sensitive phenotype. Moreover, RCAL knockdown and knockout plants did not show yield loss under normal conditions, but exhibited enhanced drought tolerance and delayed leaf senescence. The chlorophyll content, the free amino acid content and the expression of senescence-related genes in the RCAL mutant were lower than those in the wild-type plants under drought stress. In summary, Ghd2 induces leaf senescence by upregulating RCAL expression under drought stress, and the RCAL mutant has important values in breeding drought-tolerant varieties.
49.2: Invited Paper : A Transparent AMOLED with On‐cell Touch Function Driven by IGZO Thin‐Film Transistors (2011)

Abstract The performance and stability of the bottom gate coplanar type IGZO TFTs were effectively improved by the back channel treatments. A novel 2.4 inch IGZO TFTs driven transparent AMOLED was demonstrated with high transparency and resolution. Further, the on‐cell touch function was also integrated to render many interesting applications possible.
Isoquinolinone Synthesis by SNAr Reaction: A Versatile Route to Imidazo[4,5‐h]isoquinolin‐9‐ones. (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
(LV-109)READING PERFORMANCE WITH LARGE PRINT AND OPTICAL MAGNIFIERS (2000)

Bowers, Alex R. PhD1; Lovie-Kitchin, Jan E. PhD2; Woods, Russell L. PhD3 Author Information
Decreased epileptogenesis in mice lacking the System xc− transporter occurs in association with a reduction in AMPA receptor subunit GluA1 (2019)

This study provides the first evidence that Sx<sub>c</sub> <sup>-</sup> signaling contributes to epileptogenesis in the PTZ kindling model of acquired epilepsy. Further data indicate that a reduction in AMPA receptor signaling could underlie the resistance to PTZ kindling uncovered in Sx<sub>c</sub> <sup>-</sup> null mice.
ChemInform Abstract: PREPARATION AND PROPERTIES OF IRON(III)‐L‐AMINO ACID NITRATES. PART 7 (1982)

Abstract Durch Reaktion wäßriger Lösungen der Aminosäuren mit Fe(III)‐nitratnonahydrat im molaren Verhältnis 2:1 werden die Komplexe (I) erhalten (keine Ausb.‐Angaben).
Nervous vascular parallels: axon guidance and beyond (2011)

The vascular and nervous systems are organized with well defined and accurate networks, which represent the anatomical structure enabling their functions. In recent years, it has been clearly demonstrated that these two systems share in common several mechanisms and specificities. For instance, the networking properties of the nervous and vascular systems are governed by common cues that in the brain regulate axon connections and in the vasculature remodel the primitive plexus towards the vascular tree. Here, we summarize the role of semaphorins as a paradigmatic example of the role of axon guidance molecules in physiological and pathological angiogenesis. Finally, we discuss the presence in blood vessels of neurexin and neuroligin, two proteins that finely modulate synaptic activity in the brain. This observation is suggestive of an intriguing new class of molecular and functional parallels between neurons and vascular cells.
Hierarchical Behavioural Adaptable Design For Testability (2003)

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