gebhart/patrepeval huggingface dataset:
Verification methods for dense and sparse systems of equations (1994)

In this paper we describe verification methods for dense and large sparse systems of linear and nonlinear equations. Most of the methods described have been developed by the author. Other methods are mentioned, but is is not intended to give an overview over existing methods. Many of the results are published in similar form in research papers or books. In this monograph we want to give a concise and compact treatment of some fundamental concepts of the subject. Moreover, many new results are included not being published elsewhere. Among them are the following. A new test for regularity of an interval matrix is given. It is shown that it is significantly better for classes of matrices. Inclusion theorems are formulated for continuous functions not necessarily being differentiable. Some extension of a nonlinear function w.r.t. a point x is used which may be a slope, Jacobian or other. More narrow inclusions and a wider range of applicability (significantly wider input tolerances) are achieved by (i) using slopes rather than Jacobians, (ii) improvement of slopes for transcendental functions, (iii) a two-step approach proving existence in a small and uniqueness in a large interval thus allowing for proving uniqueness in much wider domains and significantly improving the speed, (iv) use of an Einzelschrittverfahren, (v) computing an inclusion of the difference w.r.t. an approximate solution. Methods for problems with parameter dependent input intervals are given yielding inner and outer inclusions. An improvement of the quality of inner inclusions is described. Methods for parametrized sparse nonlinear systems are given for expansion matrix being (i) M-matrix, (ii) symmetric positive definite, (iii) symmetric, (v) general. A fast interval library having been developed at the author's institute is presented being significantly faster compared to existing libraries. A common principle of all presented algorithms is the combination of floating point and interval algorithms. Using this synergism yields powerful algorithms with automatic result verification.
Scale invariant face detection method using higher-order local autocorrelation features extracted from log-polar image (2002)

This paper proposes a scale invariant face detection method which combines higher-order local autocorrelation (HLAC) features extracted from a log-polar transformed image with linear discriminant analysis for "face" and "not face" classification. Since HLAC features of log-polar images are sensitive to shifts of a face, we utilize this property and develop a face detection method. HLAC features extracted from a log-polar image become scale and rotation invariant because scalings and rotations of a face are expressed as shifts in a log-polar image (coordinate). By combining these features with the linear discriminant analysis which is extended to treat "face" and "not face" classes, a scale invariant face detection system can be realized.
Photoelectrochemistry of levulinic acid on undoped platinized n-titanium dioxide powders (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhotoelectrochemistry of levulinic acid on undoped platinized n-titanium dioxide powdersH. L. Chum, M. Ratcliff, F. L. Posey, J. A. Turner, and A. J. NozikCite this: J. Phys. Chem. 1983, 87, 16, 3089–3093Publication Date (Print):August 1, 1983Publication History Published online1 May 2002Published inissue 1 August 1983https://pubs.acs.org/doi/10.1021/j100239a026https://doi.org/10.1021/j100239a026research-articleACS PublicationsRequest reuse permissionsArticle Views254Altmetric-Citations27LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Sexual function and quality of life of patients affected by ovarian cancer (2019)

SF represents a fundamental aspect strictly related with QoL. Patients with ovarian cancer (as well all oncological patients) experience a reduction in their SF after diagnosis of malignancy and they should receive adequate counseling regarding this aspect.
Galaxy Alignments as a Probe of the Dynamical State of Clusters (2003)

International audience
Composite ester plasticizers. (1990)

アジピン酸ジブチエルステル及び2エチルヘキシルエステルからチタン触媒を使用し各種ジオールとエステル交換反応を行って複合エステル類composite esterを合成した. 反応モル比によって複合エステル類の組成及び粘度が異なっていた. complex esterのethanediylbisbutyl adipate, 12-propanediylbisbutyl adipate, 13-butanediylbisbutyladipateは蒸留で分離することができた. これらの複合エステル類を可塑剤として試験し可塑化効率をシートの表面硬度値から算出した. 複合エステル可塑剤は一般の可塑剤に比べ非常に低い揮発性と優れた可塑化効率を持っている. 成形物の機械強度は同じ硬度で比較すると優れておりDOPの80～90%の量の使用で同等の可塑成形物が得られると考えられる.
Discovery of Novel EPO/EPOR/JAK2 Targets and Signal Transduction Factors Via Proteomic-Based Interrogations of Post-Translational Motif Modifications (2014)

Abstract Although EPO/EPOR/JAK2 actions have been intensely studied, the majority of investigations to date have relied heavily upon conventional approaches, extant reagents and murine cell models. We therefore hypothesized that important EPOR/JAK2 targets consequently remain undiscovered, and by applying (phospho)proteomic based interrogations, have uncovered intriguing sets of new candidate mediators of EPO’s effects on human erythroid progenitor cells. Specifically, following [-] vs [+] EPO challenge, total cellular tryptic or Glu-C peptides were generated, and those post-translationally modified (PTM) due to EPO at phosphotyrosine residues (p-Y), p-TPP motifs, and MAPK plus ATK signaling nodes were isolated, and identified by duplicate tandem LC-MS/MS. EPO targets furthermore were confirmed via parallel analyses using an EPOR agonist. Known EPO/EPOR/JAK2 targets first were validated (eg., JAK2, STAT5, GAB1-3, SHIP1-3, PLCgamma, p85alpha-PI3K, LNK, SHC1, SPRY1) (and further defined with regards to specific isoforms, plus known vs novel sites of EPO-induced PTM). Beyond this, newly discovered EPO/EPOR/JAK2 regulated targets included those within the following five categories: 1] Cytoskeletal targets unexpectedly as erythroid alpha and beta spectrins (pY2332, pY15) together with pY modulation of Beta-Adducin at a calmodulin binding site (plus EPO-regulated PTM of Calmodulin per se); 2] Select EPO- regulated transcription factors, including 100-fold p-Y modulation of KLF5 at a novel transcriptional activation motif; 3] EPO/EPOR/JAK2 modulation of two new protein tyrosine phosphatase targets as PTPN18 and PTPN7; 4] Rapid EPO-induction of a notable number of novel upstream molecular adaptors including C1ORF186/”RHEX”, C1ORF150, DOK1, IRS2, SH2D2A, STAM2, SPRY2,4, DLG1,3, FRS2, AMOTL1, RAI14, CTNND1, EPS15, HGS, ITSN2, and WASL – with two novel ORF factors as C1ORF186/RHEX and C1ORF150 as prime targets in human erythroid progenitors, but absent from rat, mouse, and lower vertebrate genomes. [For C1ORF186/RHEX, select cell and molecular biological properties will be summarized]. And 5] highlighted additional novel targets (eg, transporters, metabolic regulators) that, together with the above, further emphasize a previously underestimated sophistication of EPOR/JAK2 signal transduction circuits, certain of which are proposed to be central to EPO and ESA effects on anemia (and potentially, hypertensive side-effects). Disclosures No relevant conflicts of interest to declare.
Improved field scanner incorporating parabolic optics Part 1: Simulation (2009)

An unobstructed afocal scanning system design employing two off-axis parabolic reflectors as relay optics between two flat scan mirrors is proposed and investigated using OSLO optical software. It is found that, with a symmetric arrangement of the parabolic reflectors and appropriate selection of the first scan mirror rotational axis, the system provides linear scan lines at the image surface and excellent point spread function results in all scan positions. The design is functionally equivalent to a single-mirror scan engine and superior in every metric to a comparable dimension spherical mirror arrangement. This design is suited to two-dimensional laser scan engines and for confocal and two-photon microscopy in particular.
Elastomeer-infuuspompen getest voor de praktijk (2011)

OBJECTIVE: To test short-term and long-term elastomeric infusion pumps for applicability in hospital practice and for ambulant patients at home. DESIGN AND METHODS: Four short-term elastomeric infusion pumps (Accufuser C1000M, Easypump ST 100-1, Infusor Intermate SV-100, Surefuser Plus 100 ml) and four long-term pumps (Accufuser C0100L, Easypump LT 270-24, Infusor Folfusor LV-10, Surefuser Plus 18102-01) were included in the study. Each was exploratively tested for accuracy and uniformity of the flow rate and sensitivity to external factors (temperature, fluid viscosity, height difference between pump and patient connection, filling degree), residual volume, evaporation upon storage, warming-up time and sterility. RESULTS: Flow rate of short-term pumps was less constant than of long-term pumps and displayed more deviations. For most pumps tested, the flow rate decreased in time. Flow rate increased at temperatures higher than the calibration temperature and decreased at lower temperatures. Higher fluid viscosity reduced flow rate. Differences in height between pump and patient connection up to 10 cm slightly influenced flow rate. Filling degree less than the nominal value reduced flow rate. Evaporation upon storage in the refrigerator was limited. Warming up from refrigerator to room temperature maximally required six hours. Sterility was maintained upon four weeks storage at 35°C. CONCLUSION: Flow rate of elastomeric infusion pumps was not constant and was significantly influenced by external factors. There was little difference in outcome between the pumps tested. Other factors (beyond the scope of this study), such as ease to prepare, patient-friendliness and price are also important determinants for making a choice. Principally because of the limited accuracy of the flow rate, we consider elastomeric infusion pumps less suitable for administration of cytostatic agents and pain treatment than for antibiotics.
Josephson effect through magnetic skyrmions (2015)

We discover that the multiple degrees of freedom associated with magnetic skyrmions---size, position, and helicity---can all be used to control the Josephson effect and $0\ensuremath{-}\ensuremath{\pi}$ transitions occurring in superconductor/magnetic skyrmion/superconductor junctions. In the presence of two skyrmions, the Josephson effect depends strongly on their relative helicity and leads to the possibility of a helicity-transistor effect for the supercurrent, where the critical current is changed by several orders of magnitude simply by reversing the helicity of a magnetic skyrmion. Moreover, we demonstrate that the Fraunhofer pattern can show a local minimum at zero flux as a direct result of the skyrmion magnetic texture. These findings demonstrate the rich physics that emerges when combining topological magnetic objects with superconductors and could lead to different perspectives in superconducting spintronics.
High-magnetic-field MHD-generator program. Quarterly report, April 1, 1981-June 30, 1981 (1981)

Progress in an experimental and theoretical program designed to investigate MHD channel phenomena which are important at high magnetic fields is described. The areas of research include nonuniformity effects, boundary layers, Hall field breakdown, the effects of electrode configuration and current concentrations, and studies of steady-state combustion disk and linear channels in an existing 6 Tesla magnet of small dimensions. In the study of the effects of nonuniformities, experiments have been performed to test a multi-channel, fiber optics diagnostic system that yields time-resolved temperature profiles in an MHD channel. For the study of magneto-acoustic fluctuation phenomena, a one-dimensional model has been developed to describe the performance of a non-ideal MHD generator with a generalized electrical configuration. The installation of the hardware for the data acquisition and reduction of the laser Doppler velocimeter data, to be used in the study of turbulence suppression in a magnetic field, has been nearly completed and preliminary software has been written. A two-dimensional MHD computer code has been developed which predicts the dependence on electrode and insulator dimensions of the onset of interelectrode Hall field breakdown, as initiated either by breakdown in the insulator or in the plasma. There is good agreement between calculation andmore » measurements. Calculations have been performed of the effects of nonuniformities on the flow and electrical behavior of baseload-sized disk generators. Also, predictions of the performance of baseload inflow disk generators have been calculated and compared with linear generators.« less
VCSELs: technologies et intégration photonique (2009)

Depuis le premier concept proposé par K.Iga il y a 30 ans jusqu'aux recherches actuelles sur l'intégration photonique des VCSELs (pour Lasers à Cavité Verticale à Emission par la Surface), une forte activité de recherches a été déployée sur ces composants optoélectroniques emblématiques, du matériau au composant jusqu'au système, leur permettant d'acquérir leur position stratégique actuelle. C'est dans cette dynamique que s'est inscrit mon parcours scientifique. Les principales activités de recherche que j'ai menées depuis 1992 sur la technologie des VCSELs et leur intégration dans des systèmes photoniques sont décrites dans ce mémoire. Je rappelle tout d'abord brièvement les avantages des dispositifs III-V à cavité verticale pour l'optoélectronique et plus particulièrement les propriétés des VCSELs, composants au centre de mes travaux. Ce contexte général étant posé, je décris les contraintes imposées lors de l'élaboration de ces dispositifs à cavité verticale sur GaAs ainsi que la technique de contrôle optique en temps réel qui m'a permis de répondre à ce défi. Je détaille ensuite mes travaux sur la photo-détection en cavité verticale, qui ont porté sur la conception, la réalisation et la caractérisation de photo-détecteurs simples à cavité massive, de VCSELs à double fonction pour la détection d'un faisceau externe, ainsi que de VCSELs avec monitoring intégré exploitant la détection latérale de l'émission spontanée dans le plan de la cavité. La thématique du contrôle de l'injection électrique dans les VCSELs de grandes dimensions pour la manipulation de solitons de cavité ou la génération de puissance est également exposée, ainsi que les études menées sur l'intégration des VCSELs dans les microsystèmes qui m'ont conduite à mettre en place une nouvelle filière sur la micro-optique intégrée à base de polymères pour ces composants. Enfin, les prospectives de recherche qu'ouvrent l'ensemble de ces travaux sont présentées ainsi que le contexte dans lequel elles s'inscrivent.
Advances in metal-catalysed polymerisation and related transformations (2013)

A graphical abstract is available for this content
Professionally responsible advocacy for women and children first during the COVID-19 pandemic: guidance from World Association of Perinatal Medicine and International Academy of Perinatal Medicine (2020)

The goal of perinatal medicine is to provide professionally responsible clinical management of the conditions and diagnoses of pregnant, fetal, and neonatal patients. The New York Declaration of the International Academy of Perinatal Medicine, "Women and children First - or Last?" was directed toward the ethical challenges of perinatal medicine in middle-income and low-income countries. The global COVID-19 pandemic presents common ethical challenges in all countries, independent of their national wealth. In this paper the World Association of Perinatal Medicine provides ethics-based guidance for professionally responsible advocacy for women and children first during the COVID-19 pandemic. We first present an ethical framework that explains ethical reasoning, clinically relevant ethical principles and professional virtues, and decision making with pregnant patients and parents. We then apply this ethical framework to evidence-based treatment and its improvement, planned home birth, ring-fencing obstetric services, attendance of spouse or partner at birth, and the responsible management of organizational resources. Perinatal physicians should focus on the mission of perinatal medicine to put women and children first and frame-shifting when necessary to put the lives and health of the population of patients served by a hospital first.
Artificial Neural Networks for Automated Cell Quantification in Lensless LED Imaging Systems (2018)

Cell registration by artificial neural networks (ANNs) in combination with principal component analysis (PCA) has been demonstrated for cell images acquired by light emitting diode (LED)-based compact holographic microscopy. In this approach, principal component analysis was used to find the feature values from cells and background, which would be subsequently employed as neural inputs into the artificial neural networks. Image datasets were acquired from multiple cell cultures using a lensless microscope, where the reference data was generated by a manually analyzed recording. To evaluate the developed automatic cell counter, the trained system was assessed on different data sets to detect immortalized mouse astrocytes, exhibiting a detection accuracy of ~81% compared with manual analysis. The results show that the feature values from principal component analysis and feature learning by artificial neural networks are able to provide an automatic approach on the cell detection and registration in lensless holographic imaging.
[Clinical and radiologic evaluation of periodontal changes during treatment for anterior crossbite]. (2000)

The aim of the study was to evaluate the intensity of changes in periodontium under the influence of occlusal trauma and treatment and to correlate these changes with sex and age of patient. An attempt was made to determine when treatment should be started in order to achieve optimal results. 40 patients (19 girls and 21 boys) with anterior crossbite enrolled. The patients were divided into four groups according to age: 7-9 years (group I); 10-14 years with mixed dentition (group II); 15-19 years with early permanent dentition (group III); 20 years and older (group IV). Malocclusion was diagnosed with the Index of Orthodontic Treatment Needs (IOTN) and radiographs. Periodontal status was evaluated on the basis of pocket depth measured with WHO periodontal probe, presence of pale gingival margin, mobility of teeth according to Lindhe, oral hygiene with the Plaque Index according to Sillness and Löe, and gingival bleeding with a modified method of Caton and Polson. X-ray examination was done on two occasions: before and after treatment. Orthodontic and periodontal examination were done 3 times: before treatment, immediately after treatment and 12 months after removal of active appliance. Acrylic plates were used in 38 patients. Radiographs made before and after orthodontic treatment revealed alveolar bone regeneration in the lower incisors which are antagonists of upper incisors in anterior crossbite, in groups I, II and III. The results show that improvement was easiest to achieve in the youngest group. Transient worsening of the evaluated parameters was due to corrective force of the plate. Improvement in the state of periodontium was observed when the teeth were repositioned correctly. Higher values of the evaluated indices were more often observed in girls than boys. Short treatment times make this method a very attractive alternative.
Clinical Safety of Gadoteridol, Representative of the Macrocyclic Class of Gadolinium‐Based Contrast Agents (2019)

Level of Evidence: 1 Technical Efficacy: Stage 5
Polarization-Dependent In-Line Mach–Zehnder Interferometer for Discrimination of Temperature and Ambient Index Sensitivities (2011)

Polarization-dependent in-line Mach-Zehnder interferometer fabricated by using a polarization-maintaining fiber (PMF) depending on input polarization state is investigated for discrimination of temperature and ambient index. Interference is induced by inserting the PMF with a length of 1 cm between two conventional single mode fibers. A core-misalignment method is employed to induce the interference patterns, which strongly depend on two orthogonal polarization modes. The proposed in-line Mach-Zehnder interferometer has two different transmission characteristics with different temperature (0.115 and 0.097 nm/° C for x- and y -polarization modes, respectively) and refractive index sensitivities (46.7 and 36.7 nm/RIU for x - and y -polarization modes, respectively). Accordingly, it is possible to simultaneously measure temperature and ambient index changes.
A 6.39GHz&#x2013;14GHz series resonator mode-switching oscillator with 186&#x2013;188dB FoM and 197dB FoMA in 65nm CMOS (2015)

CMOS LC voltage-controlled oscillators (VCO) with octave frequency tuning-range (FTR) are attractive for wideband radios. An area and power-efficient resonant mode-switching approach is presented that enables wide-FTR oscillators without compromising inductor Q, resulting in low phase noise and high VCO Figure-of-Merit (FoM). The proposed series resonator mode-switching approach results in a 6.4GHz to 14GHz VCO (74.6% FTR) in 65nm CMOS that achieves 186dB-188dB FoM. The scalability of this approach towards achieving even larger FTR is also demonstrated by a triple-mode 2.2GHz to 8.7GHz (119% FTR) VCO.
Whole Exome Sequencing reveals NOTCH1 mutations in anaplastic large cell lymphoma and points to Notch both as a key pathway and a potential therapeutic target (2020)

Patients diagnosed with Anaplastic Large Cell Lymphoma (ALCL) are still treated with toxic multi-agent chemotherapy and as many as 25-50% of patients relapse. To understand disease pathology and to uncover novel targets for therapy, Whole-Exome Sequencing (WES) of Anaplastic Lymphoma Kinase (ALK)+ ALCL was performed as well as Gene-Set Enrichment Analysis. This revealed that the T-cell receptor (TCR) and Notch pathways were the most enriched in mutations. In particular, variant T349P of NOTCH1, which confers a growth advantage to cells in which it is expressed, was detected in 12% of ALK+ and ALK- ALCL patient samples. Furthermore, we demonstrate that NPM-ALK promotes NOTCH1 expression through binding of STAT3 upstream of NOTCH1. Moreover, inhibition of NOTCH1 with γ-secretase inhibitors (GSIs) or silencing by shRNA leads to apoptosis; co-treatment in vitro with the ALK inhibitor Crizotinib led to additive/synergistic anti-tumour activity suggesting this may be an appropriate combination therapy for future use in the circumvention of ALK inhibitor resistance. Indeed, Crizotinib-resistant and sensitive ALCL were equally sensitive to GSIs. In conclusion, we show a variant in the extracellular domain of NOTCH1 that provides a growth advantage to cells and confirm the suitability of the Notch pathway as a second-line druggable target in ALK+ ALCL.