gebhart/patrepeval huggingface dataset:
The Effect of Low Temperature Plasma on the Properties of Foam (2005)

The effects of low temperature plasma treatment on the properties of three types of foams, polyurethane(PU), injection phylon(IP), and phylon(PH) that used for footwear mid-sole were examined. The change of surface properties of foams were characterized by electron scanning microscope, contact angle measurement, and universal testing machine. Adhesion was tested by T-peel tests of plasma treated foams/polyurethane adhesive joints. The contact angle of three types of foams were decreased dramatically with the plasma treatment time, specifically noticeable in the case of phylon(Ph). It has shown the relationship with the contact angle of phylon(PH) and the distance between electrode and samples. The peel strength of foams were increased with the increase of plasma treatment time.
A New Primate from the Middle Eocene of Myanmar and the Asian Early Origin of Anthropoids (1999)

A new genus and species of anthropoid primate, Bahinia pondaungensis gen. et sp. nov., is described from the Yashe Kyitchaung locality in the Late Middle Eocene Pondaung Formation (Myanmar). It is related to Eosimias, but it is represented by more complete remains, including upper dentition with associated lower jaw fragment. It is interpreted as a new representative of the family Eosimiidae, which corresponds to the sister group of the Amphipithecidae and of all other anthropoids. Eosimiidae are now recorded from three distinct Middle Eocene localities in Asia, giving support to the hypothesis of an Asian origin of anthropoids.
The anterior branch of the medial femoral cutaneous nerve innervates the anterior knee: a randomized volunteer trial (2023)

In half of the cases, a gap of non-anesthetized skin was present on the surgical midline incision after anesthesia of the saphenous nerve and the IFCN. This gap was covered by selective anesthesia of the MFCN-A without contribution from MFCN-P. The selective MFCN-A block may be relevant for diagnosis and interventional management of neuropathic pain due to injury of MFCN-A.
HISTOPATHOLOGICAL CLASSIFICATION OF GASTRIC CARCINOMA FOR STANDARD REPORTING SYSTEM USED IN JAPAN (1972)

Analysis of approximately 2,000 cases of gastric carcinoma which survived for more than 5 years after gastrectomy revealed that the histopathological classification system proposed by the Japanese Society for Gastric Cancer Research had fair prognostic value and can be recommended for general use.
Computational model of chimeric antigen receptors explains site-specific phosphorylation kinetics (2018)

Abstract Chimeric antigen receptors (CARs) have recently been approved for the treatment of hematological malignancies, but our lack of understanding of the basic mechanisms that activate these proteins has made it difficult to optimize and control CAR-based therapies. In this study, we use phospho-proteomic mass spectrometry and mechanistic computational modeling to quantify the in vitro kinetics of individual tyrosine phosphorylation on a variety of CARs. We show that each of the ten tyrosine sites on the CD28-CD3ζ CAR is phosphorylated by LCK with distinct kinetics. The addition of CD28 at the N-terminal of CD3ζ increases the overall rate of CD3ζ phosphorylation. Our computational model identifies that LCK phosphorylates CD3ζ through a mechanism of competitive inhibition. This model agrees with previously published data in the literature and predicts that phosphatases in this system interact with CD3ζ through a similar mechanism of competitive inhibition. This quantitative modeling framework can be used to better understand CAR signaling and T cell activation.
Molecular cloning of cDNA sequences for avian malic enzyme. Nutritional and hormonal regulation of malic enzyme mRNA levels in avian liver cells in vivo and in culture. (1983)

A double-stranded cDNA library constructed from the total poly(A+) RNA of goose uropygial gland was screened for recombinants containing sequences complementary to malic enzyme mRNA. Replicate arrays of 1400 colonies were hybridized independently with 32P-labeled cDNAs copied from two populations of hepatic RNA derived from tissues which differed by about 35-fold with respect to the relative synthesis of malic enzyme. Forty-eight of the colonies which gave differential signals were further screened by hybrid-selected translation. DNA from one of these contained an insert of 970 base pairs and selected an mRNA which directed the synthesis of malic enzyme in a cell-free system. The malic enzyme sequences were subcloned into the single-stranded bacteriophage M13mp8. The subclones were used to prepare 32P-labeled single-stranded hybridization probe. Northern analysis indicated that malic enzyme mRNA from both goose and chicken is about 2100 bases in length. Hepatic malic enzyme mRNA concentration is stimulated 30- to 50-fold or more when neonatal chicks or goslings, respectively, are fed for 24 h. When added to chick embryo hepatocytes in culture, triiodothyronine stimulated malic enzyme mRNA accumulation by more than 100-fold. Glucagon inhibited the thyroid hormone-stimulated accumulation of malic enzyme mRNA by 99%. In all instances, malic enzyme mRNA concentration was closely correlated with the relative rate of malic enzyme synthesis. These results suggest that nutritional and hormonal regulation of malic enzyme synthesis occurs at the pretranslational level.
Globalization and the Market for Teammates (1998)

The globalization of firms is explored at theoretical and empirical levels. The idea is that a global firm is a multi-cultural team. The existence of a global firm is somewhat puzzling. Combining workers who have different cultures, legal systems, and languages imposes costs on the firm that would not be present were all workers to conform to one standard. In order to offset the costs of cross-cultural dealing, there must be complementarities between the workers that are sufficiently important to overcome the costs. Disjoint and relevant skills create an environment where the gains from complementarities can be significant. It is also necessary that teammates be able to communicate with one another. The search for the best practice' is analyzed and empirical support from an examination of trading patterns is provided.
Comparative evaluation of linear and nonlinear Model Predictive Control for a isolated high power DC/DC converter (2010)

This paper compares the computational time and closed loop system performances for linear and nonlinear Model Predictive Control (MPC) of the full bridge DC/DC converter under starting, overload and load step change conditions. The control objective is to regulate the output voltage without violating the peak current constraint. The experimental results reveal that both linear and nonlinear MPC algorithms can successfully achieve voltage regulation and peak current protection. Considering the algorithm complexity, the closed loop performance and the necessary computational time, the nonlinear MPC scheme is more desirable than the linear MPC for this application.
Characterizing Anion Adsorption to Aqueous Interfaces: Toluene–Water versus Air–Water (2021)

We continue our investigation of the behavior of simple ions at aqueous interfaces, employing the combination of two surface-sensitive nonlinear spectroscopy tools, broadband deep UV electronic sum-frequency generation and UV second harmonic generation, to characterize the adsorption of thiocyanate to the interface of water with toluene─a prototypical hydrophobe. We find that both the interfacial spectrum and the Gibbs free energy of adsorption closely match results previously reported for the air-water interface. We observe no relative spectral shift in the higher-energy CTTS transition of thiocyanate, implying similar solvation environments for the two interfaces. Similarly, the Gibbs free energies of adsorption agree within error; however, we expect the respective enthalpic and entropic contributions to differ between the two interfaces, similar to our earlier findings for the air-water versus graphene-water interfaces. Further experiments and theoretical modeling are necessary to quantify the mechanistic differences.
Avon (1978)

Avon covers an area previously divided between the County Boroughs of Bristol and Bath and the counties of Somerset and Gloucestershire. Most of its boundaries are natural—the River Severn (west), the Mendips (south) and the Cotswold escarpment (east). The two urban centres are the commercial, industrial, cathedral and university city of Bristol and the city of Bath which, although smaller, extends an influence well into Wiltshire.KeywordsCounty CouncilHospital FacilityMajor AccidentPublic Open SpaceCouncil HouseThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Aquisição fonológica do Português Brasileiro em crianças do Rio de Janeiro (2012)

The information collected may ultimately help speech-language pathologists in the assessment and treatment of children with speech sound disorders.
Investigation of splitting SPP modes propagating at metal-dielectric interface (2004)

This paper describes surface plasmon polariton (SPP) modes that show extraordinary propagation behaviors along metal stripes with finite width, including multiple energy condensations. Phenomenological and quantitative investigations are carried out on these behaviors. Images of SPP modes at output edges for wide stripes exhibit multiple spots that spanned the lateral side of the stripes. The spot number is monotonously decreased as the stripe length increases. Besides, the input versus output power ratio shows a stepwise change as changing the propagation distance. We present a model of SPP modes to explain these behaviors.
A Pickup and Delivery Problem Based on AVL and GIS (2003)

The fundamental design issues that arise in the pickup and delivery system planning are optimizing the system with minimum cost and maximum throughput and service level. This study is concerned with the development of pickup and delivery system with customer responsive service level, DCM(Demand Chain Management). The distribution process and service map are consisted of manufacturing, warehousing, and pickup and delivery. First we formulated the vehicle pickup and delivery problem using GIS-VRP method so as to satisfy the customer service requests. Second, we developed a GUI-type computer program using AVL, automated vehicle location system. The computational results show that the proposed method is very effective on a set of test problems.
Infrared face recognition: a comprehensive review of methodologies and databases (2014)

Automatic face recognition is an area with immense practical potential which includes a wide range of commercial and law enforcement applications. Hence it is unsurprising that it continues to be one of the most active research areas of computer vision. Even after over three decades of intense research, the state-of-the-art in face recognition continues to improve, benefitting from advances in a range of different research fields such as image processing, pattern recognition, computer graphics, and physiology. Systems based on visible spectrum images, the most researched face recognition modality, have reached a significant level of maturity with some practical success. However, they continue to face challenges in the presence of illumination, pose and expression changes, as well as facial disguises, all of which can significantly decrease recognition accuracy. Amongst various approaches which have been proposed in an attempt to overcome these limitations, the use of infrared (IR) imaging has emerged as a particularly promising research direction. This paper presents a comprehensive and timely review of the literature on this subject. Our key contributions are: (i) a summary of the inherent properties of infrared imaging which makes this modality promising in the context of face recognition, (ii) a systematic review of the most influential approaches, with a focus on emerging common trends as well as key differences between alternative methodologies, (iii) a description of the main databases of infrared facial images available to the researcher, and lastly (iv) a discussion of the most promising avenues for future research.
Novel configuration of a myosin II transient intermediate analogue revealed by quick-freeze deep-etch replica electron microscopy (2012)

In the present paper, we described our attempt to characterize the rough three-dimensional features of the structural analogue of the key intermediate of myosin's cross-bridge cycle. Using quick-freeze deep-etch replica electron microscopy, we observed that actin-attached myosin during in vitro sliding was bent superficially as postulated by the conventional hypothesis, but in the opposite direction of the putative pre-power-stroke configuration, as for ADP·Vi (inorganic vanadate)-bound myosin. We searched for the conformational species with a similar appearance and found that SH1-SH2 (thiols 1 and 2)-cross-linked myosin is a good candidate. To characterize such small asymmetric structures, we employed a new pattern-recognition procedure that accommodates the metal-replicated samples. In this method, the best-matched views of the target microscopic images were selected from a comprehensive set of images simulated from known atomic co-ordinates of relevant proteins. Together with effective morphological filtering, we could define the conformational species and the view angles of the catalytic domain and the lever arm cropped from averaged images of disulfide-cross-linked myosin. Whereas the catalytic domain of the new conformer closely resembled the pPDM (N,N'-p-phenylenedimaleimide)-treated, but SH2 Lys705-cross-linked, structure (PDB code 1L2O), a minor product of the same cross-linking reaction, the lever arm projected differently. Using separately determined view angles of the catalytic domain and the lever arm, we built a model of disulfide-cross-linked myosin. Further combination with the 'displacement-mapping' procedure enabled us to reconstruct the global three-dimensional envelope of the unusual structure whose lever arm orientation is compatible with our reports on the actin-sliding cross-bridge structure. Assuming this conformer as the structural analogue of the transient intermediate during actin sliding, the power stroke of the lever arm might accompany the reversal of the disorganized SH1 helix.
Bi-thread microcontroller as digital signal processor (2002)

A bi-thread pipeline RISC microcontroller working together with a simple but efficient arithmetic coprocessor is proposed as digital signal processor. The structure has a Dual Architecture in which the main thread is used to manage the interfacing process and to run the algorithm and the slave thread is used only to control the "hard" computation in the arithmetic coprocessor that performs the sum of products. For coprocessor we have a sequential machine with a good mean working time. The paper presents the machine architecture and the associated organisation.
Peptide Assisted Imprinting for Turn-On Fluorescence Detection of Proteins (2019)

Current limitations in protein imprinting technology above all rely on poor cavity control for sensing purpose [1,2]...
Chemistry course companion : IB diploma programme (2007)

Libro de texto para estudiantes del bachillerato internacional (IBDP, International Baccalaureate Diploma Programme) en el área de Química según el plan de estudios del 2007. Incluye los temas básicos del programa (química analítica cuantitativa, estructura atómica, periodicidad, enlaces y estructura, energética, cinética, equilibrio, ácidos y bases, oxidación y reducción, química orgánica, incertidumbre y error en las medidas), temas de nivel avanzado (química analítica moderna, bioquímica humana, química en la industria y la tecnología, medicinas y drogas, química medioambiental, química de los alimentos, química orgánica), y preguntas prácticas tipo examen con respuestas para evaluar el progreso de los alumnos.
Genetic algorithm tuned adaptive discrete-time sliding mode controller for grid-connected inverter with an LCL filter (2022)

The development of a two-stage cascaded control strategy for a single-phase grid-connected inverter with an LCL filter based on inverter-side current is proposed. The main objective of the proposed controller is to minimize both the grid current tracking error and the current total harmonic distortion and to overcome the system resonance introduced because of the third-order LCL filter. In the first part, a feed-forward controller calculates the reference values for the system states at the steady-state operation with no external disturbance. In contrast, an adaptive discrete-time sliding mode controller is used for disturbance rejection caused by parameter uncertainties in the second stage. The proposed control approach also considers the nonlinear behavior of the pulsed nature of the inverter’s hard switching pulse width modulation modulator. The grid-side current is taken as in-phase to the grid voltage for the inverter-side reference values calculation. Numerical simulation and experimental tests were performed to validate the proposed control strategy’s faster dynamic response under external disturbances and parametric uncertainties. An improvement of approximately 18% in THD was recorded against the variation of grid-side impedance ranging from 50%–150% over the conventional discrete sliding mode control These results demonstrate the robustness and effectiveness of the proposed controller to integrate the solar photovoltaic energy sources seamlessly.
Driver's Cognition in Peripheral Field of View (1993)

&lt;div class="htmlview paragraph"&gt;This paper concerns driver's burden for visual information processing in which his central vision is coupled with his peripheral one. A visual driving simulator was applied to the first step of the study, where driver's responses to both central and peripheral tasks were simultaneously investigated.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;The series of test indicate that the driver's responsiveness to the central and peripheral tasks could define the whole burden for visual information processing. Therefore, it appears that the responsiveness to the peripheral vision could be more or less compromised to support the central one.&lt;/div&gt;
Cross-Over Trials in Clinical Research (1994)

Preface to the Second Edition Preface to the First Edition 1. Introduction 2. Some Basic Considerations Concerning Estimation in Clinical Trials 3. The AB/BA Design with Normal Data 4. Other Outcomes and the AB/BA Design 5. Normal Data from Designs with Three or More Treatments 6. Other Outcomes from Designs with Three or More Treatments 7. Some Special Designs 8. Graphical and Tabular Presentation of Cross-over Trials 9. Various Design Issues 10. Mathematical Approaches to Carry-over References Author Index Subject Index
Vaccination of MSI-H colorectal cancer patients with frameshift peptide antigens: A phase I/IIa clinical trial. (2014)

e14530 Background: High level microsatellite instability (MSI-H) occurs in 15% of colorectal cancers as a consequence of DNA mismatch repair deficiency. MSI-H colorectal cancers are characterized by a dense immune cell infiltration, which is compatible with a pronounced anti-tumoral immune response. MSI-H cancers are characteristic of the inherited HNPCC (hereditary non-polyposis colorectal cancer) or Lynch syndrome, but can also develop sporadically. In MSI-H cancers, DNA mismatch repair deficiency causes insertion or deletion mutations at coding microsatellites, which may lead to shifts of the translational reading frame and to the generation of MMR deficiency-related frameshift peptides (FSPs). Expression of FSP antigens is restricted to MMR-deficient cells; therefore, FSP antigens are promising targets of vaccination approaches. Methods: We have recently initiated a clinical phase I/IIa vaccination trial that evaluates vaccination with a combination of three FSP antigens (derived from frameshift variants of the coding microsatellite-containing genes AIM2, HT001, TAF1B) in the clinical setting. Inclusion criteria allow vaccination of patients with history of metastasized colorectal cancer (UICC stage III or IV) after the end of standard chemotherapy. Phase I of the trial evaluates safety and toxicity as the primary endpoint (6 patients); phase IIa addresses the induction of cellular and humoral immune responses (16 patients). Results: Data from phase I demonstrate that no FSP antigen-associated severe adverse events have been observed after FSP vaccination. Significant induction of FSP-specific T cell immune responses was observed in 3 out of 4 evaluated patients. Antibody responses against FSP antigens were significantly induced in 9 out of 10 evaluated patients. Conclusions: If vaccination with FSPs turns out to be well tolerated and leads to the induction of effector T cell immune responses, FSP vaccination may represent a promising novel approach for treatment of MSI-H colorectal cancer patients and for tumor prevention in Lynch syndrome mutation carriers. Clinical trial information: NCT01461148.
Learning Physical-Layer Communication With Quantized Feedback (2019)

Data-driven optimization of transmitters and receivers can reveal new modulation and detection schemes and enable physical-layer communication over unknown channels. Previous work has shown that practical implementations of this approach require a feedback signal from the receiver to the transmitter. In this paper, we study the impact of quantized feedback on data-driven learning of physical-layer communication. A novel quantization method is proposed, which exploits the specific properties of the feedback signal and is suitable for non-stationary signal distributions. The method is evaluated for linear and nonlinear channels. Simulation results show that feedback quantization does not appreciably affect the learning process and can lead to similar performance as compared to the case where unquantized feedback is used for training, even with 1-bit quantization. In addition, it is shown that learning is surprisingly robust to noisy feedback where random bit flips are applied to the quantization bits.
Model-based variables for the kinematic assessment of upper-extremity impairments in post-stroke patients (2016)

This study identified a set of measures capable of extensively characterizing the kinematics of upper limb movements performed by post-stroke subjects and of tracking changes of different motor improvement aspects throughout the rehabilitation process.