gebhart/patrepeval huggingface dataset:
The Interaction of Akt with APPL1 Is Required for Insulin-stimulated Glut4 Translocation (2007)

APPL1 (adaptor protein containing PH domain, PTB domain, and leucine zipper motif 1) is an Akt/protein kinase B-binding protein involved in signal transduction and membrane trafficking pathways for various receptors, including receptor tyrosine kinases. Here, we establish a role for APPL1 in insulin signaling in which we demonstrate its interaction with Akt2 by co-immunoprecipitation and pulldown assays. In primary rat adipocytes and skeletal muscle, APPL1 and Akt2 formed a complex that was dissociated upon insulin stimulation in both tissues. To investigate possible APPL1 function in adipocytes, we analyzed Akt phosphorylation, 2-deoxyglucose uptake, and Glut4 translocation by immunofluorescence following APPL1 knockdown by small interfering and short hairpin RNAs. We show that APPL1 knockdown suppressed Akt phosphorylation, glucose uptake, and Glut4 translocation. We also tested the effect in 3T3-L1 adipocytes of expressing full-length APPL1 or an N- or a C-terminal APPL1 construct. Interestingly, expression of full-length APPL1 and its N terminus suppressed insulin-stimulated 2-deoxyglucose uptake and Glut4 translocation to roughly the same extent (40-60%). We confirmed by cellular fractionation that Glut4 translocation was substantially blocked in 3T3-L1 adipocytes transfected with full-length APPL1. By cellular fractionation, APPL1 was localized mainly in the cytosol, and it showed a small degree of re-localization to the light microsomes and nucleus in response to insulin. By immunofluorescence, we also show that APPL1 partially co-localized with Glut4. These data suggest that APPL1 plays an important role in insulin-stimulated Glut4 translocation in muscle and adipose tissues and that its N-terminal portion may be critical for APPL1 function.
Plasma levels of TNF-alpha soluble receptors correlate with outcome in human falciparum malaria. (1994)

Plasma from immune (residents of malaria infested areas) and non immune (European travellers) patients suffering from cerebral malaria, severe or mild, was analyzed for the presence of soluble tumor necrosis factor receptors. On admission of the subjects, sTNF-R55 and sTNF-R75 levels were significantly elevated in all groups and correlated with TNF-alpha. Except for sTNF-R55 whose levels were higher in severe than in mild malaria, no correlation was observed between soluble receptors and clinical status. Nevertheless, sTNF-R55 and sTNF-R75 were significantly more elevated in patients who died (10.7 +/- 2.3 ng/ml and 94.9 +/- 31 ng/ml, respectively) than in those surviving (5.5 +/- 0.4 ng/ml and 37.4 +/- 5.4 ng/ml respectively). A marked correlation was observed between soluble receptors levels and some biological markers of gravity like creatinine, urea, and bilirubin. In 13 non immune patients, circulating soluble receptors levels decreased significantly after 7 days when clinical and biological malaria features had disappeared, but TNFsR75 remained above normal levels. After a fortnight of treatment in 17 immune patients, sTNF-R55 and sTNF-R75 remained elevated. However, the ratios of TNF-alpha/s TNF-R55 and 75 were not higher in the cases of cerebral malaria or fatal outcome. Further studies are required to determine if elevated levels of sTNF-R55 and sTNF-R75 are beneficial, due to the inhibition of TNF-alpha or whether they are detrimental since they stabilize this deleterious cytokine.
Perovskite Solar Cells with Polyaniline Hole Transport Layers Surpassing a 20% Power Conversion Efficiency (2021)

Hole transport layers (HTLs) in perovskite photovoltaics do not just play a key role in device performance; they also determine the overall flexibility, cost, and opportune tandem solar cell applications. Currently used HTLs have limited functionality and are costly. Here, we develop an efficient bifunctional and cost-effective HTL based on electrochemically deposited polyaniline (PAN) decorated with dodecyl benzene sulfonic acid. We then resurface PAN with chlorine to improve HTL conductivity and to provide nucleation sites for the growth and passivation of perovskite films. The synergetic modification on the perovskite/PAN interface and crystallographic/optoelectric properties of the perovskite film delivers a photovoltaic efficiency of 20.7% for a small-area inverted cell, the highest among any polyaniline-based perovskite solar cells. An efficiency of 18.4% is achieved for 1 cm2 devices. This work provides a competitive category of in situ passivasive HTLs for efficient and scalable perovskite solar cells.
In-Situ based Trajectory Editing Method of a 3D Object for Digilog Book Authoring (2010)

디지로그 북(Digilog book)은 기존 서적과 디지털 콘텐츠을 융합함으로써, 아날로그적 감성과 디지털 오감을 함께 제공하는 증강현실기반 차세대 출판물이다. 디지로그 북을 저작할 수 있는 저작 소프트웨어인 아틀렛(ARtalet)은 증강현실 환경에서 3 차원 사용자 인터페이스를 이용한 직관적인 In-Situ 저작 환경을 제공한다. 본 논문은 디지로그 북에 증강된 3D 객체에 이동 경로를 생성하고 조작 할 수 있는, 아틀렛 저작 환경 기반의 이동 궤적 편집 기법을 제안한다. 구체적으로 이동 궤적의 조정점(Control point)을 적절히 할당하기 위해서 3차원 조작도구의 이동 좌표에 대하여 조정점 할당 검사를 한다. 그리고 부드러운 곡선 형태로 이동 궤적을 복원하기 위해서 스플라인을 이용한 보간 과정을 수행한다. 또한 작고 밀집된 이동 궤적의 조정점을 효과적으로 선택하기 위해서 동적 스코어(Score)를 기반으로 한 조정점 선택 방법을 적용한다. 실험 결과 제안한 방법은 기존 방법에 비해 오차와 완료시간은 유의한 차이가 없었지만, 조정점의 수를 약 90% 이상 감소시킬 수 있었다. 이것은 매우 적은 수의 조정점만으로도 이동궤적을 복원할 수 있으며 추후 이동 궤적 조작에 필요한 조정점의 조작 횟수를 대폭 줄일 수 있다는 것을 의미한다. 또한 제안한 방법은 기존의 조정점 조작 방법에 비해 상대적으로 적은 손과 팔의 움직임만으로도 빠르게 이동 궤적의 형태를 변경 할 수 있었다. 본 논문에서 제안한 3D 객체의 이동 궤적 편집 방법은 몰입형 In-Situ 증강현실 환경의 교육, 게임, 디자인, 애니메이션, 시뮬레이션 등의 분야에서 드로잉 또는 곡선 편집 방법으로 응용될 수 있다.
Olfactory Receptor Sequence Polymorphism Within and Between Breeds of Dogs (2005)

Olfactory receptors, to which odorant molecules specifically bind, are encoded by the largest gene family yet identified in the mammalian genome. We investigated additional polymorphism due to the possible existence of multiple alleles dispersed in different dog breeds by carrying out a survey of the sequences of 16 olfactory receptor genes in a sample of 95 dogs of 20 different breeds. The level of polymorphism was high--all genes were found to have allelic variants--leading to amino acid changes and pseudogenization of some alleles in a number of cases. This preliminary study also revealed that some alleles are breed specific (or rare in the dog population), with some representing the major allele in the breeds concerned.
Improved Kick Management During MPD by Real-Time Pore-Pressure Estimation (2009)

Abstract Pressure maintenance within safe bounds and minimization of influx of fluids from the formation to the well during a kick are basic concerns of well control. Managed Pressure Drilling (MPD) offers improved capabilities over conventional well control methods to address these concerns. In this work we develop a methodology that capitalizes on the improved access to down-hole measurements offered by wired drill pipe telemetry, to maintain pressure within desired bounds during kick management. The objective of this methodology is to improve MPD by reducing non productive time, reducing formation damage and optimizing operational limits for the annular back pressure choke manifold. The proposed methodology estimates formation pore pressure automatically based on real-time measurements when a gas kick is taken during MPD. The methodology relies on the characteristics of the pressure build-up curve. Implementation of the methodology presumes the availability of standard MPD equipment for automatic annular back pressure control. A representative North-Sea well is used as test case geometry and an advanced hydraulics model is used as a virtual well in computer simulations that provide the basis for the presented results. The proposed methodology is demonstrated to both maintain pressure within desirable bounds and reduce formation fluid influx during a kick and thereby prevent the risk of hole stability problems and the cost associated with non-productive time.
Preparation of [(1-<i>x</i>)PbTiO<sub>3</sub>+<i>x</i>MgO] Thin Films by rf-Magnetron Sputtering Method and Their Electrical Conductivity (1990)

Highly c-axis oriented thin films with compositions of [(1-x)PbTiO3+xMgO] (x=0.015-0.090) were prepared by the rfmagnetron sputtering method. A few physical and electrical properties of these thin films obtained were studied PMT thin films of 1μm thickness showed that the degree of c-axis orientation α were approximately 0.8 and independent of compositionx. On the other hand, from the relationship between α and film thickness on the PMT thin films with x=0.030, α showed a tendency to decreased with increasing film thickness. It is considered that these thin films are successfully grown with good heteroepitaxy on MgO substrates from the RHEED pattern of PMT thin film with x=0.030. A range of I∝Vn, where n≥2, was observed at high electric field below 250°C in I-V characteristics. This was considered to be due to an effect of vacancy in thin films. Apparent activation energy Ua of PMT thin films agreed with those of PMT single crystals and direct current resistivity ρ of films exhibited rather large values compared with those of single crystals.
A new nonblocking photonic switching network (2002)

In this paper, a new switch architecture is proposed for nonblocking photonic switching. The switch is a space division multistage network using 2/spl times/2 optical switching elements, which may be directional couplers, fabricated on titanium diffused lithium niobate (Ti:LiNbO/sub 3/) substrates. The idea behind the proposed architecture and a recursive definition for it are presented. Some properties of the switch are derived and analyzed. The performance of the switch is also discussed and compared with other well-known designs.
Changes in Plasma Estrogen, Luteinizing Hormone, Follicle-Stimulating Hormone and 13, 14-Dihydro-15-Keto-Prostaglandin F2α during Blockade of Luteolysis in Pigs after human Chorionic Gonadotropin Treatment1 (1983)

An injection of human chorionic gonadotropin (HCG) or estrogen on d 12 of the estrous cycle delays luteolysis in the pig. In an experiment to determine if HCG stimulated estrogen secretion, 21 cyclic pigs received one of five different amounts of HCG-(A) 0, (B) 125, (C) 250, (D) 500 or (E) 1,000 IU-as a single, im injection in 2 ml of distilled water on d 12 of the estrous cycle. Blood was collected from the jugular vein immediately before HCG injection and once daily thereafter until d 20 of the estrous cycle. Plasma progesterone, estrogen (unconjugated) and 13,14-dihydro-15-keto-prostaglandin F2 alpha (PGFM) were quantified for pigs in all groups; luteinizing hormone (LH) and follicle-stimulating hormone (FSH) were quantified for pigs in groups A and E. The HCG injection exerted a dose-related increase on the mean interestrus interval (groups A, B, C, D and E were 20.5, 20.2, 22.5, 31.0 and 61.4 d, respectively) and on the delay of luteolysis as measured by mean plasma progesterone on d 16 (A, B and C vs D and E, respectively, 1.9, 1.2 and 10.4 vs 34.1 and 47.1 ng/ml; P less than .05). The HCG injection caused a transitory increase in plasma estrogen from d 12 (5 to 10 pg/ml before treatment) to d 15 (35.5 pg/ml, group D) and to d 16 (90.2 pg/ml, group E) before it decreased to preinjection levels on d 17 (group D) and 18 (group E).(ABSTRACT TRUNCATED AT 250 WORDS)
OxIOD: The Dataset for Deep Inertial Odometry (2018)

Advances in micro-electro-mechanical (MEMS) techniques enable inertial measurements units (IMUs) to be small, cheap, energy efficient, and widely used in smartphones, robots, and drones. Exploiting inertial data for accurate and reliable navigation and localization has attracted significant research and industrial interest, as IMU measurements are completely ego-centric and generally environment agnostic. Recent studies have shown that the notorious issue of drift can be significantly alleviated by using deep neural networks (DNNs), e.g. IONet. However, the lack of sufficient labelled data for training and testing various architectures limits the proliferation of adopting DNNs in IMU-based tasks. In this paper, we propose and release the Oxford Inertial Odometry Dataset (OxIOD), a first-of-its-kind data collection for inertial-odometry research, with all sequences having ground-truth labels. Our dataset contains 158 sequences totalling more than 42 km in total distance, much larger than previous inertial datasets. Another notable feature of this dataset lies in its diversity, which can reflect the complex motions of phone-based IMUs in various everyday usage. The measurements were collected with four different attachments (handheld, in the pocket, in the handbag and on the trolley), four motion modes (halting, walking slowly, walking normally, and running), five different users, four types of off-the-shelf consumer phones, and large-scale localization from office buildings. Deep inertial tracking experiments were conducted to show the effectiveness of our dataset in training deep neural network models and evaluate learning-based and model-based algorithms. The OxIOD Dataset is available at: http://deepio.cs.ox.ac.uk
Congenital Stationary Night Blindness With Negative Electroretinogram (1986)

An analysis of 64 patients with congenital stationary night blindness showed that all had essentially normal fundi. Electroretinography (ERG) showed a normal a wave with extremely reduced b wave (negative type) when recorded with a single bright white stimulus in the dark. We classified these patients into two groups based on the evaluation of rod ERG and/or psychophysical dark adaptation measured with an 11 degree test target at 15 degrees in the upper part of the retina. One group (35 patients) lacked rod function (complete type). Nine patients could not be classified. No pedigree showed a complete and incomplete type in one family. Differences between the two groups in refractive error, photopic function, and oscillatory potentials in the ERG suggest a different pathogenesis. Our analysis may provide a new classification of congenital stationary night blindness with a negative ERG.
A new genus of Empididae (Diptera) with enlarged postpedicels in mid-Cretaceous Burmese amber (2020)

A new genus and species of Empididae (Diptera) in mid-Cretaceous Burmese amber is described as Neoalavesia hadroceria gen. et sp. nov. in the subfamily Atelestinae. The male is characterised by its small size, unique wing venation with reduced cell dm and the greatly expanded postpedicels that may have been used as sexual attractants. A novel feature of the fossil is a small, elongate, glutinous structure containing numerous filiform, sperm-like bodies adjacent to the abdominal terminus.
Der Einfluß der Calcium‐, Phosphor‐ und Vitamin D‐Zufuhr auf die Cadmium‐Retention in Leber und Nieren beim wachsenden Huhn (1984)

Zusammenfassung An Hühnerküken wurde der Einfluß unterschiedlicher Konzentrationen von Calcium (0,6%, 1,0% und 1,4%), Phosphor (0,7% und 1%) und Vitamin D 3 (750 und 1500 I.E./kg Futter) im Futter auf die Cadmiumretention in Leber und Nieren untersucht. Dem Futter wurden 0,3; 1; 3; 9 und 27 mg Cd/kg als CdCl 2 zugesetzt. Mit steigendem Cadmiumgehalt im Futter erhöhte sich die Cadmiumkonzentration in den Organen. Der Anstieg war nur im Bereich von 0,3 bis 9 ppm in etwa linear, darüber nimmt die Retentionsrate mit steigender Cadmiumkonzentration im Futter zu. In der Leber wurden etwa halb so hohe Konzentrationen wie in den Nieren gemessen. Ein Einfluß des Cadmiums auf Gesundheitszustand und Mastleistung sowie auf die Serumcalciumwerte wurde nicht eindeutig festgestellt, wohl aber eine Verminderung der Aktivität des Calcium‐bindenden Proteins der Dünndarmmucosa bei 27 ppm Cadmium im Futter Es bestand eine starke Abhängigkeit der Cadmiumretention sowohl in den Nieren als auch in der Leber vom Calcium‐ und Phosphorgehalt des Futters. Eine adäquate Calciumversorgung verringerte die Cadmiumkonzentration in den Nieren auf die Hälfte gegenüber einer leichten Unterversorgung mit Calcium. Durch ein weites Verhältnis Ca:P (1,4:0,7) konnte die Cadmiumretention gegenüber knapper Calciumversorgung (0,6:0,7) auf ein Viertel verringert werden. Erhöhte Vitamin D‐Gabe wirkte sich bei Calciummangel fördernd, bei normaler bis reichlicher Calciumgabe jedoch hemmend auf die Rückstandsbildung in den Nieren aus.
Effects of grid-placed contacts on circuit performance (2003)

The impact of grid-placed contacts on application-specific integrated circuit (ASIC) performance is studied. Although snapping contacts to grid adds restrictions during layout design, smaller circuit area can be achieved by careful selection of the grid pitch, raising the lower limit of transistor width, applying double exposure, and shrinking the minimum contact pitch enabled by more effective application of resolution enhancement technologies. The technique is demonstrated on the contact level of 250-nm standard cells with the minimum contact pitch shrunk by 10%. The area change of 84 cells ranges from -20% to 25% with a median decrease of 5%. The areas of two circuits, a finite-impulse-response (FIR) filter and an add-compare-select (ACS) unit in the Viterbi decoder, decrease by 4% and 2% respectively. Delay and power consumption are also estimated to decrease with area.
A new two-dimensional electron gas base transistor (2DEG-HBT) (1987)

A new two-dimensional electron gas (2DEG) base pnp-type AlGaAs/GaAs heterobipolar transistor (2DEG-HBT) has been proposed and fabricated for the first time. This is the first monolithic fabrication of HBT and 2DEG-FET. 2DEG-HBT is a new functional device, a 'bitransistor', operating as both Bipolar and FET. This bitransistor action is achieved by a new device operation principle:the 2DEG at the AlGaAs/GaAs heterointerface acts as either base for Bipolar or n-channel for FET. 2DEG-HBT will open a new field of high speed and low power-oriented BiCMOS-like GaAs LSIs.
Temporal Decline in Pathogen-Mediated Release of Methyl Salicylate Associated With Decreasing Vector Preference for Infected Over Uninfected Plants (2018)

Asian citrus psyllid Diaphorina citri Kuwayama is the vector of the phytopathogenic bacteria Candidatus Liberibacter asiaticus (CLas). D. citri is attracted to methyl salicylate (MeSA) that is emitted by CLas-infected citrus. MeSA is catalyzed from salicylic acid (SA) by salicylic acid methyl transferase (SAMT). In addition, salicylate hydroxylase, an enzyme that degrades SA and suppresses host plant defense, is unregulated in CLas-infected as compared with uninfected citrus. Based on these findings, we hypothesized that CLas-induced plant volatile emissions and SAMT expression may decrease over time following CLas infection. We first identified the putative Citrus sinensis SAMT (CsSAMT) that methylates SA to MeSA. Thereafter we compared MeSA emission and SAMT expression between uninfected citrus, citrus recently ( 1year) CLas-infected citrus. We found that MeSA emission increased in citrus recently infected with CLas, whereas both MeSA emissions and SAMT expression decreased in long-infected citrus. In behavioral assays, D. citri preferred settling in asymptomatic citrus recently infected with CLas rather than on uninfected citrus trees or long-infected trees. We conducted olfactometer assays that showed that the odor of citrus recently infected with CLas was more attractive to psyllid than the odor of uninfected citrus of long-infected trees. We linked the preference for citrus odor recently infected with CLas to the increase of MeSA emission following CLas infection. Overall, our study demonstrated pulsed changes in citrus odor following CLas infection. These changes affected the behavior of the CLas vector. Our study confirms previous reports demonstrating that plant defenses boosted following phytopatogen infection tend to decrease over time. Implications on the CLas epidemic are discussed.
Carbonylchlorobis(tri-tert-butylphosphine)rhodium: a simple rhodium(I) complex which is not square-planar? (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCarbonylchlorobis(tri-tert-butylphosphine)rhodium: a simple rhodium(I) complex which is not square-planar?Richard L. Harlow, Stephen A. Westcott, David L. Thorn, and R. Thomas BakerCite this: Inorg. Chem. 1992, 31, 2, 323–326Publication Date (Print):January 1, 1992Publication History Published online1 May 2002Published inissue 1 January 1992https://pubs.acs.org/doi/10.1021/ic00028a038https://doi.org/10.1021/ic00028a038research-articleACS PublicationsRequest reuse permissionsArticle Views109Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
1H AND31P NMR Spectroscopy of Agrocinopine (1986)

Abstract The 1H NMR data of agrocinopine in D2O solution as extracted from standard 2D NMR experiments, along with 1D 31P and 13C NMR experiments allow to support the trisaccharide structure originally proposed on basis of comparative 13C NMR measurements.
Capacitance of KOH activated carbide-derived carbons (2009)

Chemical activation of CDC leads to capacitance values in an organic electrolyte as high as 180 F/g, 30% larger than those of as-produced samples, due to the surface area and microporosity development occurring as a consequence of the activation.
A systematic assessment of the quality of reporting for platelet transfusion studies (2010)

Recently published articles of clinical PLT transfusion share common strengths and weaknesses. The quality of reporting may be improved by providing guidelines to authors and journal editors that list the essential elements of a well-reported clinical study of PLT transfusion.
1P327 Mechanical force-dependent zyxin accumulation leads to actin polymerization at focal adhesions(11. Morphogenesis and cell adhesion,Poster Session,Abstract,Meeting Program of EABS & BSJ 2006) (2006)

Larninins are rnain component of extracellular matrix.
Optical Amplifiers for Multi–Band Optical Transmission Systems (2021)

Opening new wavelength bands is the most economic step for further increasing the capacity of optical transmission links. Characteristics of different amplifier technologies for signal amplification in different wavelength bands are detailed. In particular, the suitability of these technologies for short–term and mid–term implementation is considered. An important criterion is the availability of qualified components, notably the required pump laser diodes. On this basis, solutions for the near–term and the mid–term are discussed.
ChemInform Abstract: Hole Transport in Sensitized CdS—NiO Nanoparticle Photocathodes. (2011)

Abstract NiO nanostructured films are prepared by the spin‐casting method from slurries of NiO powder followed by sintering at 450 °C.