gebhart/patrepeval huggingface dataset:
Multiresolution Modeling For The Analysis Of Acoustic Transients (2005)

This paper presents a new framework for the modeling and analysis of dynamic stochastic pro- cesses that evolve on multiple time scales: Hyperstate models. Hyperstate models are generalizations of dis- crete hidden Markov models. They explicitly model pro- cess dynamics at multiple time scales in a computation- ally tractable, hierarchical way. The formulation leads to a statistically rigorous, computationally efficient op- timal nonlinear filtering algorithm for discrete nonsta- tionary processes. The technique has been applied to a variety of problems, including automated analysis of acoustic transients. The transient analysis uses a multi- stage approach that extracts short-term features from the input acoustic time series, translates them into sym- bol classes, then analyzes the stochastic dynamics of the symbol sequences on multiple time scales to detect and classify acoustic signals. In this paper the general model- ing and filtering technique is outlined, and results of the application of Hyperstate modeling to acoustic transient data analysis from an at-sea experiment are presented.
Hexaamminecobalt(III)–Hydrogen Ion Exchange in α- and θ-Zirconium Phosphates with Various Particle-size Distribution (1985)

Abstract The hexaamminecobalt(III)–hydrogen ion exchange in zirconium phosphates was studied by means of the batch method, mainly with regard to the particle-size distribution of zirconium phosphates. α-Zirconium phosphates were prepared by the direct-precipitation method. The degree of ion exchange increased with the fineness of the zirconium phosphates used. The ion exchange proceeded to a lesser extent in highly crystalline α-zirconium phosphate. θ-Zirconium phosphate with the interlayer distance of 10.4 Å took up the complex cation selectively and easily. Fifty percent of the protons in the θ-zirconium phosphate were thus replaced with hexaamminecobalt(III), and the interlayer distance was expanded to 11.2 Å.
Elaboration and Luminescence Properties of Laser-Heated Pedestal Growth Sr3Al2O6-Based Fibers (2022)

The development of transparent optical fibers represents one of the biggest scientific challenges for a wide variety of modern technologies ranging from communication systems to medical applications. Here, transparent Sr3Al2O6 crystalline fibers have been grown by the laser-heated pedestal growth (LHPG) technique and the effect of using unconventional glass or ceramic seed is discussed. These fibers exhibit a unique micro- and nanostructure made of veins dispersed in a single-oriented Sr3Al2O6 crystalline matrix, which has been thoroughly characterized by using electron backscatter diffraction and high-resolution transmission electron microscopy. The LHPG method also successfully produced optical fibers of 1 at% Er3+-doped Sr3Al2O6. Even when other impurity was detected, the emission spectrum of the fiber presented sharp Er3+ emission bands and long fluorescence lifetime values arising from the high crystalline structure perfection provided by the LHPG method.
Joint calibration of frequency selective time variant I/Q-imbalance and modulator DC-offset error in broadband direct-conversion transmitters (2009)

Recently, much attention has been paid to frequency selective I/Q-imbalance, which can seriously limit the performance of broadband direct-conversion transceivers and degrade the baseband pre-linearization of the power amplifier in the transmitter. This paper addresses the issue of joint calibration of frequency selective I/Q-imbalance and modulator DC-offset error in the transmitter. The presented parameter estimation requires no pilot signal, making the calibration ldquosemi-blindrdquo and standard-independent. The proposed digital pre-equalization is very simple. Moreover, the I/Q-imbalance is modeled as slowly time-variant and a seamless I/Q-imbalance and DC-offset error parameter tracking algorithm is developed. The effectiveness of the proposed algorithms is verified by numerical simulations.
Evaluation of a passive pediatric leg exoskeleton during gait (2020)

Exotendon-based exoskeletons may provide an alternative solution for optimizing gait in therapy and in the community for children with hemiparesis. Determining the optimal stiffness and configuration for each child is an important area of future research.
Management of Sciatica (2017)

This interactive feature on the management of sciatica offers a case vignette accompanied by essays that support recommending either lumbar disk surgery or nonsurgical treatment, including physical therapy.
[Usefulness and limitations of 99mTc-MIBI scintigraphy for detection of parathyroid lesions]. (1997)

To evaluate the usefulness of MIBI scintigraphy (MIBI) for parathyroid lesions, the detectability of lesions by MIBI was compared with that by Tl-Tc subtraction imaging, ultrasonography, CT and MRI in 56 histologically proved lesions. In neck lesions, ultrasonography (92%) and MIBI (85%) showed better detectability than those by the other three modalities. With MIBI, detectability was decreased for smaller parathyroid lesions that coexisted with thyroid disease. Among the five modalities, MIBI showed the highest detectability (88%) for ectopic or metastatic lesions. The smallest parathyroid lesions detected by MIBI were a parathyroid adenoma weighing 220mg and a parathyroid hyperplasia weighing 200mg. MIBI was thought to be more valuable for ectopic or metastatic parathyroid lesions.
Securing Remote Policy Enforcement by a Multi-Enclave based Attestation Architecture (2021)

The concept of usage control goes beyond traditional access control by regulating not only the retrieval but also the processing of data. To be able to remotely enforce usage control policy the processing party requires a trusted execution environ-ment such as Intel SGX which creates so-called enclaves. In this paper we introduce Multi Enclave based Code from Template (MECT), an SGX-based architecture for trusted remote policy enforcement. MECT uses a multi-enclave approach in which an enclave generation service dynamically generates enclaves from pre-defined code and dynamic policy parameters. This approach leads to a small trusted computing base and highly simplified attestation while preserving functionality benefits. Our proof of concept implementation consumes customisable code from templates. We compare the implementation with other architectures regarding the trusted computing base, flexibility, performance, and modularity. This comparison highlights the security benefits for remote attestation of MECT.
Preclinical and clinical evaluation of autonomic function in humans (2016)

This review focuses on how to assess autonomic function in humans including various ways to measure heart rate, catecholamines, and sympathetic neural activity. The need to assess autonomic function is paramount in many experimental paradigms because of the following. (1) Autonomic dysfunction is present in common diseases like hypertension, diabetes and heart failure, and the magnitude of this dysfunction is broadly related to morbidity and mortality in these disorders. (2) The relationship between autonomic dysfunction and morbidity and mortality can be causal. (3) Interventions that modulate or reverse autonomic dysfunction can improve outcomes in the affected patients. The techniques discussed are also frequently used to understand the autonomic response to sympathoexcitatory manoeuvres like exercise, the cold pressor test or mental stress. Because these manoeuvres can engage a variety of sensory and efferent pathways, under some circumstances the physiological responses measured by many of the techniques are directionally similar, in others they are divergent. Thus any investigator seeking to study the autonomic nervous system or its contribution to either normal physiology or pathophysiological conditions must carefully balance a number of considerations to ensure that the right technique is used to address the question of interest.
Thrombus formation: stability matters (2006)

Comment on Cosemans et al, page [3045][1] 

In this issue, Cosemans and colleagues demonstrate that ADP-dependent signaling via PI3K promotes sustained integrin activation and thrombus stability, as well as contributing to the onset of platelet aggregation. 

Much of the effort to understand
Expression of CD226 Antagonizes Apoptotic Cell Death in Murine Thymocytes (2009)

CD226 is known to be expressed on many types of peripheral lymphoid cells and involved in T cell differentiation, activation, and cytotoxicity. In this study, we report that CD226 is also expressed on mouse thymocytes at varying developmental stages, and its expression is associated with resistance of thymocytes to apoptosis. The levels of CD226 expression appeared to be closely coupled with thymocyte development, in that it was preferentially expressed on CD4(+)CD8(-) and CD4(-)CD8(+) thymocytes at all stages during mouse development, and was markedly increased on the cells in neonatal mice. Of the CD4(+)CD8(+) population, CD226 was predominantly expressed by the cells also positive for CD69, suggesting that CD226 expression may be induced in thymocyte-positive selection. Inhibition of CD226 by short hairpin RNA in a fetal thymus organ culture model led to reduced thymus cellularity, which was associated with enhanced apoptotic cell death. In contrast, CD226-transgenic mice displayed enlarged thymus lobes resulting from increased thymus cellularity. CD226 on thymocytes seemed to play a role in regulating the expression of survivin, as inhibition of CD226 down-regulated survivin, but overexpression of CD226 rescued thymocytes from apoptosis through up-regulation of survivin. In addition, overexpression of CD226 reduced sensitivity of EL-4 thymoma cells to apoptosis by up-regulating the expression of survivin. Taken together, these results indicate that CD226 is an antiapoptotic molecule and may play an important role in murine thymocyte development.
Simulation of multimodal optical and acoustic communications in underwater networks (2015)

In this paper, we consider data muling over a network of fixed sensors by employing a mobile Autonomous Underwater Vehicle (AUV). We approach the problem using both acoustic and optical communications together in a multi-modal hybrid network: the most appropriate physical layer is chosen according to the quality of the transmissions that take place over time. We consider three distinct cases of water type: clear, coastal and turbid water, in order to test the system behavior under different conditions. The ambient light noise is realistically reproduced via the Hydrolight software and taken into account, due to its important contribution to the optical SNR in shallow waters. Finally, we simulate the performance of the system using the DESERT Underwater framework during missions of interest in different channel conditions and network depth. Our results show the effectiveness of a multi-modal underwater network in the cases of clear and coastal waters.
Modified Algorithm for Standardization of Near-Infrared Spectrometric Instruments (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTModified Algorithm for Standardization of Near-Infrared Spectrometric InstrumentsE. Bouveresse, D. L. Massart, and P. DardenneCite this: Anal. Chem. 1995, 67, 8, 1381–1389Publication Date (Print):April 15, 1995Publication History Published online1 May 2002Published inissue 15 April 1995https://pubs.acs.org/doi/10.1021/ac00104a013https://doi.org/10.1021/ac00104a013research-articleACS PublicationsRequest reuse permissionsArticle Views164Altmetric-Citations61LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Mapping properties of the discrete fractional maximal operator in metric measure spaces (2013)

This work studies boundedness properties of the fractional maximal operator on metric measure spaces under standard assumptions on the measure. The main motivation is to show that the fractional maximal operator has similar smoothing and mapping properties as the Riesz potential. Instead of the usual fractional maximal operator, we also consider a so-called discrete maximal operator which has better regularity. We study the boundedness of the discrete fractional maximal operator in Sobolev, Hölder, Morrey, and Campanato spaces. We also prove a version of the Coifman– Rochberg lemma for the fractional maximal function.
Abstract 54: Characterization of patient-derived organoids cultured on a gas-rich, liquid-liquid interface (2019)

Modeling tissues in vitro has long consisted of two-dimensional (2D) monolayer cultures grown in a dish, flask, or multi-well plate. While these methods remain adequate for some applications, the advent of personalized cancer therapies has necessitated the development of more complex models that more accurately represent the in vivo environment. Attempting to characterize tumor cell biology and response to candidate pharmaceuticals in 2D cultures has led to results that fail to translate to clinical therapies. A key source of this failure is the loss of cell diversity due to selective pressure resulting in cell populations that favor adhering to a rigid substrate. Three-dimensional (3D) cell culture methods have produced models that capture many of the dynamics of the in vivo tissue environment. Patient-derived organoids (PDOs) are quickly becoming the most attractive solution for creating predictive, patient-specific tumor models in vitro. Typically grown as spheroids, these models still present limitations in terms of cell survival and recapitulation of tumor development.Lena Biosciences has previously developed complex, vascularized tissue models using patented 3D scaffolds and a perfusion system. Hepatocytes grown in this system demonstrated increased cell viability and recovery of cytochrome P450 enzyme activity compared to 2D controls. Integral to the perfusion system is a pure, synthetic liquid that is twice as dense as and immiscible with cell culture medium and reagents. It is permissive to atmospheric gases, providing a gas-rich, liquid-liquid interface below 3D cultures maintained in the system. We hypothesized that PDOs could be cultured without a 3D scaffold, directly at the interface between the cell culture medium and this synthetic liquid. A specific preparation of this interface resulted in lung-derived PDOs that spontaneously formed dense, 3D, tissue-like structures that showed increased viability (as measured by a 50% reduction in LDH release) and cellular respiration (three-fold increase as measured by an alamarBlue assay). Ongoing studies are focused on characterizing PDOs from other patients and other tissues as they develop in long-term in vitro studies. Should this PDO model prove to be a faithful representation of in vivo tumor development, this system would be ideal for applications such as testing drug efficacy and studying mechanisms of tumor metastasis.Citation Format: James T. Shoemaker, Katherine R. Richardson, Jamie Arnst, Adam Marcus, Jelena Vukasinovic. Characterization of patient-derived organoids cultured on a gas-rich, liquid-liquid interface [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 54.
Plant cell culture secondary matabolism : toward industrial application (1996)

Screening of Plant Cell Cultures for New Industrially Interesting Compounds, J. Schripsema, S.Y. Fung, and R. Verpoorte Large-Scale Production of Secondary Metabolites by Plant Cell Cultures, J.E. Schlatmann, H.J.G. ten Hoopen, and J.J. Heijnen Machine Vision and Automation in Secondary Metabolite Bioprocess Control, M.A.L. Smith and J.F. Reid Industrial Application of Biotransformation Using Plant Cell Cultures, M. Yokoyama Production of Antitumor Compounds by Plant Cell Cultures, M. Misawa and A.E. Goodbody Production of Paclitaxel and Related Taxoids in Cell Cultures of Taxus cuspidata: Perspectives for Industrial Applications, A.G. Fett-Neto and F. DiCosmo Development of Process Strategies for Anthocyanin-Based Food Colorant Production Using Vitis vinifera Cell Cultures, F. Cormier, F. Brion, C.B. Do, and C. Moresoli Research on the Production of Useful Compounds by Plant Cell Cultures in Japan, Y. Hara Plant Cell Biotechnological Research in The Netherlands, R. Verpoorte Index
Effects of steroids and lubricants on electrical impedance and tissue response following cochlear implantation (2007)

The present study examined the effects of steroids and lubricants on electrical impedance and tissue response following cochlear implantation in animal models. Guinea pigs were implanted following either no treatment, or intrascalar injection with dexamethasone, triamcinolone, sodium hyaluronate or saline. Cats were implanted following either no treatment, or intrascalar injection with dexamethasone, triamcinolone or a mixture of triamcinolone with sodium hyaluronate. In guinea pigs, impedance changes and intracochlear tissue response were less for the hyaluronate and saline groups. In cats, impedance in the dexamethasone group increased similar to non-treated cats. Impedance of triamcinolone treated cats remained low for about two months after implantation, before increasing to levels similar to the other groups. Significant fibrous tissue growth was observed histologically. The results of the present study indicate that a single intracochlear application of hyaluronate or triamcinolone may postpone, but will ultimately not prevent the rise in impedance following cochlear implantation.
Spin-polarized reflection of electrons in a two-dimensional electron system (2003)

We present a method to create spin-polarized beams of ballistic electrons in a two-dimensional electron system in the presence of spin-orbit interaction. Scattering of a spin-unpolarized injected beam from a lithographic barrier leads to the creation of two fully spin-polarized side beams, in addition to an unpolarized specularly reflected beam. Experimental magnetotransport data on InSb/InAlSb heterostructures demonstrate the spin-polarized reflection in a mesoscopic geometry, and confirm our theoretical predictions.
A fast object detector based on high-order gradients and Gaussian process regression for UAV images (2015)

Unmanned aerial vehicles (UAVs) acquire images characterized by an exceptional level of detail, which calls for processing and analysis methods capable of efficiently exploiting their rich information content. In particular, the detection of specific classes of objects (e.g. cars, roofs) represents an important but challenging task for these images. Most of the related literature has aimed at proposing methods capable of providing satisfactory detection accuracies. However, they typically refer to a specific class of objects and give little attention to the processing time. In this work, we present a novel and fast methodological alternative. In addition to being particularly fast, the proposed method is a general detection approach that can be customized to any class of objects after an opportune training phase. It consists of the design of a non-linear filter that combines image gradient features at different orders and Gaussian process (GP) modelling. High-order image gradients permit one to capture detailed information regarding the structure of the investigated class of objects. The GP model fed with high-order gradients yields an estimate of the presence of the object of interest for a given position of the sliding window within the image. Two separate sets of experiments were conducted, each aiming at assessing the proposed method to detect a given class of objects common in urban scenarios, namely vehicles and solar panels, respectively. Results on real UAV georeferenced images characterized by 2 cm resolution and by three channels (red, green, and blue (RGB)) are provided and discussed, showing particularly interesting properties of the detector.
An ethnobotanical survey of medicinal plants used in the East Sepik province of Papua New Guinea (2015)

Documentation of consistent plant use argues for efficacy and is particularly important since established and effective herbal medicinal interventions are sorely needed in the rural areas of PNG, and unfortunately clinical validation for the same is often lacking. Despite the existence of a large corpus of medical annotation of plants for PNG, previously unknown medical uses of plants can be uncovered. Furthermore, comparisons of medicinal plant utilization is possible if databases are reformatted for consistencies that allow comparisons. A concerted effort in building easily comparable databases could dramatically facilitate ethnopharmacological analysis of the existing plant diversity.
Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli (2009)

Behavioral responses to painful stimuli require peripheral sensory neurons called nociceptors. Electrophysiological studies show that most C-fiber nociceptors are polymodal (i.e., respond to multiple noxious stimulus modalities, such as mechanical and thermal); nevertheless, these stimuli are perceived as distinct. Therefore, it is believed that discrimination among these modalities only occurs at spinal or supraspinal levels of processing. Here, we provide evidence to the contrary. Genetic ablation in adulthood of unmyelinated sensory neurons expressing the G protein-coupled receptor Mrgprd reduces behavioral sensitivity to noxious mechanical stimuli but not to heat or cold stimuli. Conversely, pharmacological ablation of the central branches of TRPV1(+) nociceptors, which constitute a nonoverlapping population, selectively abolishes noxious heat pain sensitivity. Combined elimination of both populations yielded an additive phenotype with no additional behavioral deficits, ruling out a redundant contribution of these populations to heat and mechanical pain sensitivity. This double-dissociation suggests that the brain can distinguish different noxious stimulus modalities from the earliest stages of sensory processing.
Disentangling Ionization Processes by Two-Color Phase Contrast Strong Field Photoelectron Spectroscopy (2016)

We demonstrate a method to retrieve and visualize low-energy rescattering signals from the total photoelectron momentum map by Fourier decomposition of angle-resolved two-color strong field photoionization.