gebhart/patrepeval huggingface dataset:
A mixture model-based real-time audio sources classification method (2017)

Recent research on machine learning focuses on audio source identification in complex environments. They rely on extracting features from audio signals and use machine learning techniques to model the sound classes. However, such techniques are often not optimized for a real-time implementation and in multi-source conditions. We propose a new real-time audio single-source classification method based on a dictionary of sound models (that can be extended to a multi-source setting). The sound spectrums are modeled with mixture models and form a dictionary. The classification is based on a comparison with all the elements of the dictionary by computing likelihoods and the best match is used as a result. We found that this technique outperforms classic methods within a temporal horizon of 0.5s per decision (achieved 6% of errors on a database composed of 50 classes). Future works will focus on the multi-sources classification and reduce the computational load.
Peritonitis, dialysate infusion and lung function in continuous ambulatory peritoneal dialysis (CAPD). (1985)

Pulmonary function tests were done in seven CAPD patients with acute peritonitis on the day of admission to the hospital and after recovery. Subsequently, the effect of dialysate infusion alone on lung function was studied in 19 patients initiated on CAPD and nine of these patients were restudied 7.6 +/- 4.1 months later. Peritonitis was associated with a 30% reduction in vital capacity and a significant fall in arterial oxygen tension (7 to 11 mmHg) (p less than 0.01). Dialysate infusion alone decreased functional residual capacity (FRC) and produced small changes in PaO2 which were more pronounced in the supine position. The decrease in PaO2 observed in changing from sitting prior to dialysate infusion, to supine after dialysate infusion was due to the development of airways closure at resting lung volumes. Follow-up studies in nine patients demonstrated a continued and significant fall in FRC with dialysate infusion, without however, any changes in PaO2. We conclude that peritonitis in CAPD patients is accompanied by significant changes in lung function which are probably due to a decrease in diaphragmatic mobility resulting in atelectasis and underventilation of dependent lung zones. In CAPD patients without peritonitis, dialysate infusion in the supine position produces significant changes in PaO2, but with time, compensatory mechanisms develop to abolish the changes in PaO2.
Prospective multiple outcomes study of outpatient lumbar microdiscectomy: should 75 to 80% success rates be the norm? (2002)

The findings of this study support the evidence that lumbar microdiscectomy performed on an outpatient basis is a very safe and effective means of treating sciatic pain due to disc herniation. The authors believe that their outcome success rates of 75 to 80% are more realistic than those of 90% or more found in some reports.
Nuclear Power: Levels of Safety (1988)

The rise and fall of the nuclear power industry in the United States is a well-documented story with enough socio-technological conflict to fill dozens of scholarly, and not so scholarly, books. Whatever the reasons for the situation we are now in, and no matter how we apportion the blame, the ultimate choice of whether to use nuclear power in this country is made by the utilities and by the public. Their choices are, finally, based on some form of risk-benefit analysis. Such analysis is done in well-documented and apparently logical form by the utilities and in a rather more inchoate but not necessarily less accurate form by the public. Nuclear power has failed in the United States because both the real and perceived risks outweigh the potential benefits. The national decision not to rely upon nuclear power in its present form is not an irrational one. A wide ranging public balancing of risk and benefit requires a classification of risk which is clear and believable for the public to be able to assess the risks associated with given technological structures. The qualitative four-level safety ladder provides such a framework. Nuclear reactors have been designed which fit clearly and demonstrably into each of the possible qualitative safety levels. Surprisingly, it appears that safer may also mean cheaper. The intellectual and technical prerequisites are in hand for an important national decision. Deployment of a qualitatively different second generation of nuclear reactors can have important benefits for the United States. Surprisingly, it may well be the "nuclear establishment" itself, with enormous investments of money and pride in the existing nuclear systems, that rejects second generation reactors. It may be that we will not have a second generation of reactors until the first generation of nuclear engineers and nuclear power advocates has retired.
College Enrollment and Completion Among Nationally Recognized High‐Achieving Hispanic Students (2016)

Abstract Hispanic high school graduates have lower college completion rates than academically similar white students. As Hispanic students have been theorized to be more constrained in the college search and selection process, one potential policy lever is to increase the set of colleges to which these students apply and attend. In this paper, we investigate the impacts of the College Board's National Hispanic Recognition Program (NHRP), which recognizes the highest‐scoring 11th‐grade Hispanic students on the PSAT/NMSQT, as a mechanism of improving college choice and completion. The program not only informs students about their relative ability, but it also enables colleges to identify, recruit, and offer enrollment incentives. Overall, we find that the program has strong effects on college attendance patterns, shifting students from two‐year to four‐year institutions, as well as to colleges that are out‐of‐state and public flagships, all areas where Hispanic attendance has lagged. NHRP shifts the geographic distribution of where students earn their degree, and increases overall bachelor's completion among Hispanic students who traditionally have had lower rates of success. These results demonstrate that college outreach can have significant impacts on the enrollment choices of Hispanic students and can serve as a policy lever for colleges looking to draw academically talented students.
Template‐Free Hydrothermal Synthesis of Mesoporous MgO Nanostructures and Their Applications in Water Treatment (2012)

The controlled synthesis of Mg(OH)(2) nanowires and microflowers composed of nanoplates was successfully achieved by a template-free hydrothermal synthetic method. It was found that the reaction medium played a crucial role in the morphological control of the precursor nanostructures. The high polarity of water molecules favored the polar growth of the precursor, resulting in the formation of nanowires with a diameter of 80 nm, whereas a mixed water/ethanol medium with a lower degree of polarity led to the formation of microflowers. Moreover, mesoporous MgO nanostructures could be obtained by further annealing these as-prepared precursors in air at 500 °C for 2 h. During thermal treatment, the wire- and flower-like morphologies were retained. Porosity formation was due to thermal decomposition of Mg(OH)(2) and release of H(2)O. Both the mesoporous MgO nanowires and microflowers showed superior ability of adsorbing the organic dye methyl orange, and thus they are promising candidates for polluted water treatment.
Low-voltage CMOS transductance cell based onparallel operation of triode and saturation transconductors (1994)

Recently a new linearity improvement technique for low voltage CMOS transconductors was proposed (by Coban, A.L. in Elect. Lett., vol. 30, p. 1124, 1994). Tne technique is based on the parallel operation of a triode and saturation transconductor.The authors comment on this paper. >
Exploration of Tumor-Suppressive MicroRNAs Silenced by DNA Hypermethylation in Oral Cancer (2008)

In the last few years, microRNAs (miRNA) have started a revolution in molecular biology and emerged as key players in the carcinogenesis. They have been identified in various tumor types, showing that different sets of miRNAs are usually deregulated in different cancers. To identify the miRNA signature that was specific for oral squamous cell carcinoma (OSCC), we first examined expression profiles of 148 miRNAs in a panel of 18 OSCC cell lines and the immortalized oral keratinocyte line RT7 as a control. Compared with RT7, the expression of 54 miRNAs (36.5%) was frequently down-regulated in OSCC lines (<0.5-fold expression, >or=66.7% of 18 lines). Among these 54 miRNAs, we further analyzed four of these miRNAs (i.e., miR-34b, miR-137, miR-193a, and miR-203), located around CpG islands, to identify tumor-suppressive miRNAs silenced through aberrant DNA methylation. The expression of those four genes was restored by treatment with 5-aza-2'-deoxycytidine in OSCC cells lacking their expression. In addition, expression levels of the four miRNAs were inversely correlated with their DNA methylation status in the OSCC lines. In primary tumors of OSCC with paired normal oral mucosa, down-regulation of miRNA expression through tumor-specific hypermethylation was more frequently observed for miR-137 and miR-193a than for miR-34b and miR-203. Moreover, the ectopic transfection of miR-137 or miR-193a into OSCC lines lacking their expressions significantly reduced cell growth, with down-regulation of the translation of cyclin-dependent kinase 6 or E2F transcription factor 6, respectively. Taken together, our results clearly show that miR-137 and miR-193a are tumor suppressor miRNAs epigenetically silenced during oral carcinogenesis.
IBM System Storage Ds3000: Introduction and Implementation Guide (2009)

This IBM Redbooks publication introduces the IBM System Storage DS3000, providing an overview of its design and specifications, and describing in detail how to set up, configure, and administer it. Since the DS3000 has different disk attachment options, we describe these different methods, including SAS and Fibre Channel. You will learn how to install the DS3000 Storage Manager, and how to use its GUI and command-line options. We cover quick setup of the DS3000: creating arrays and logical drives and making the storage available to a hosts. You will also find advanced management tasks, including setting up and managing FlashCopy and Volume Copy. Finally, we provide several configuration scenarios. The scenarios describe different methods for attaching various DS3000 models under Windows and Linux , including clustered and boot-from-SAN environments. These examples include step by step instructions using both the GUI as well as command-line scripts. This publication is intended for customers, IBM Business Partners, and IBM technical professionals who want to learn more about the capabilities and advanced functions of the DS3000 Series of storage servers with Storage Manager Software. It also targets those who have a DS3000 storage system and need detailed advice on how to configure and manage it.
A Real‐Time Tracking, Notification, and Web‐based Enrollment System for Emergency Department Research (2004)

The authors describe the development of a real-time tracking, notification, and Web-based enrollment system designed specifically to facilitate emergency department research. The system was developed in a cooperative arrangement between an emergency medicine researcher and a medical information software company. The system design and utilization are described as well as the security measures to ensure compliance with Health Insurance Portability and Accountability Act (HIPAA) regulations and database security.
BOLT: Energy-efficient Out-of-Order Latency-Tolerant execution (2010)

LT (latency tolerant) execution is an attractive candidate technique for future out-of-order cores. LT defers the forward slices of LLC (last-level cache) misses to a slice buffer and re-executes them when the misses return. An LT core increases ILP without physically scaling the issue queue and register file and increases MLP without additional software threads that can reduce cache performance. Unfortunately, proposed LT designs are not energy efficient. They require too many additional structures and they defer and re-execute too many instructions to justify their performance gains. In this paper, we address these inefficiencies. We introduce a microarchitecture called BOLT (Better Out-of-Order Latency-Tolerance) that implements LT as an alternative use of SMT (Simultaneous Multi-Threading). We also present a new slice buffer organization and traversal scheme that increases performance and reduces overhead by pruning instances of useless and redundant LT. Collectively, these modifications turn out-of-order LT into a technique that improves performance in an energy-efficient way.
Applying time modulation to the joint transform correlator (1994)

A major limitation on the optical joint transform correlator (JTC) is that the output plane is dominated by unwanted autocorrelation products. A new technique is proposed that uses time modulation and demodulation to separate the correlation components. Time modulation is applied to the JIG inputs, resulting in a time-modulated joint power spectrum. Demodulation of the transform plane separates the self-correlation components from the other terms. When the demodulated signal is the input to the second transform stage in the JTC the result is system peak-to-noise ratio/peak-to-secondary ratio (PNR/PSR) improvement, removal of input plane location constraints, and elimination of detection problems resulting from multiple targets. Two implementations are discussed. Using a general model for sinusoidal modulation, it is shown that amplitude, phase, and polarization modulation of the inputs all result in amplitude modulation of the correlation signals in the transform plane. The general solution is difficult to implement, because it requires temporal demodulation of the joint Fourier signal on a pixel-by-pixel basis. A more practical system results from the case of square-wave modulation, where it is shown that demodulation can be easily implemented through image subtraction using only two to four frames of data. This Fourier plane processing technique has been implemented using a binary JTC (BJTC). Performance improvement of 6 dB over the conventional BJTC is demonstrated through computer simulation and laboratory results.
Metabolism of cyclic phenones in rainbow trout in vitro assays (2019)

1. Cyclic phenones are chemicals of interest to the USEPA due to their potential for endocrine disruption to aquatic and terrestrial species.2. Prior to this report, there was very limited information addressing metabolism of cyclic phenones by fish species and the potential for estrogen receptor (ER) binding and vitellogenin (Vtg) gene activation by their metabolites.3. The main objectives of the current research were to characterize rainbow trout (rt) liver slice-mediated <i>in vitro</i> metabolism of model parent cyclic phenones exhibiting disparity between ER binding and ER-mediated Vtg gene induction, and to assess the metabolic competency of fish liver <i>in vitro</i> tests to help determine the chemical form (parent and/or metabolite) associated with the observed biological response.4. GC-MS, HPLC and LC-MS/MS technologies were applied to investigate the <i>in vitro</i> biotransformation of cyclobutyl phenyl ketone (CBP), benzophenone (DPK), cyclohexyl phenyl ketone (CPK) mostly in the absence of standards for metabolite characterization.5. It was concluded that estrogenic effects of the studied cyclic phenones are mediated by the parent chemical structure for DPK, but by active metabolites for CPK. A definitive interpretation was not possible for CBP and CBPOH (alcohol), although a contribution of both structures to gene induction is suspected.
Emission and Focusing Characteristics of a Quintuple-Gated Field Emitter Array (2011)

A field emitter array (FEA) with a five-stacked gate electrode, that is, a quintuple-gated FEA with a four-stacked electrode lens, was fabricated. The four-stacked electrode forms an einzel lens, where the second and third electrodes are connected through a contact hole. Because the electron velocity of the einzel lens in a quintuple-gated FEA is smaller than for the quadruple-gated FEA, the quintuple-gated FEA has a stronger electron convergence. The slit sweeping method confirmed that a beam crossover is formed for the quintuple-gated FEA.
Development of the School-Aged Life Impact Burn Recovery Evaluation (SA-LIBRE5–12) Profile: A Conceptual Framework (2021)

Pediatric burn injuries can alter the trajectory of the survivor's entire life. Patient-centered outcome measures are helpful to assess unique physical and psychosocial needs and long-term recovery. This study aimed to develop a conceptual framework to measure pediatric burn outcomes in survivors aged 5 to 12 years as a part of the School-Aged Life Impact Burn Recovery Evaluation Computer Adaptive Test (SA-LIBRE5-12 CAT) development. This study conducted a systematic literature review guided by the WHO International Classification of Functioning-Child and Youth and domains in the American Burn Association/Shriners Hospitals for Children Burn Outcomes Questionnaire5-18. Interviews with eight parents and seven clinicians were conducted to identify important domains in child recovery. One clinician focus group with four clinicians was completed to identify gaps in the preliminary framework, and semiweekly expert consensus meetings were conducted with three experts to solidify the framework. Qualitative data were analyzed by grounded theory methodology. Three major thematic outcome domains emerged: 1) Physical Functioning: fine motor and upper extremity, gross motor and lower extremity, pain, skin symptoms, sleep and fatigue, and physical resilience; 2) Psychological Functioning: cognitive, behavioral, emotional, resilience, and body image; and 3) Family and Social Functioning: family relationships, and parental satisfaction, school, peer relations, and community participation. The framework will be used to develop item banks for a CAT-based assessment of school-aged children's health and developmental outcomes, which will be designed for clinical and research use to optimize interventions, personalize care, and improve long-term health outcomes for burned children.
Case 36-2018: A 29-Year-Old Man with an Incidentally Discovered Renal Mass (2018)

A 29-year-old man was evaluated for a new, self-identified left testicular mass. Genitourinary ultrasonography revealed a varicocele on the left side and an incidental complex right renal mass measuring 11 cm in diameter. Diagnostic and management decisions were made.
Pancreatic tumor detection using hypericin-based fluorescence spectroscopy and cytology (2005)

Hypericin is a novel, highly fluorescent photosensitizer that exhibits selective tumor cell uptake properties and is particularly resistant to photobleaching. In this study, we have characterized hypericin uptake in human pancreatic tumor cells with relation to incubation time, cell number, and drug concentration. <i>Ex vivo</i> hypericin based fluorescence spectroscopy was performed to detect the presence of MIA PaCa-2 pancreatic tumor cells in the peritoneal cavity of BALB/c nude mice, as well as to quantify gross tumor burden. Hypericin based cytology of peritoneal lavage samples, using both one and two photon laser confocal microscopy, demonstrated more than a two-fold increase in fluorescence emission of pancreatic tumor cells as compared to control samples. <i>In vitro</i> treatment of pancreatic cancer cells with hypericin based photodynamic therapy showed tumor cell cytotoxicity in a drug dose, incident laser power, and time dependent manner. For these experiments, a continuous wavelength solid-state laser source (532 nm) was operated at power levels in the range of 100-400 mW. Potential applications of hypericin in tumor diagnosis, staging, and therapy will be presented.
The development of pyrrolobenzodiazepines as antitumour agents (2011)

The culmination of over four decades of study on structure-activity relationships of PBDs has led to a detailed understanding of how to introduce structural modification to enhance biological activity and potency. The challenge for the next phase in the development of the PBDs is to harness this activity and potency in a new generation of cancer therapeutics.
Collaborative Human-Robot Exploration via Implicit Coordination (2022)

This paper develops a methodology for collaborative human-robot exploration that leverages implicit coordination. Most autonomous single- and multi-robot exploration systems require a remote operator to provide explicit guidance to the robotic team. Few works consider how to embed the human partner alongside robots to provide guidance in the field. A remaining challenge for collaborative human-robot exploration is efficient communication of goals from the human to the robot. In this paper we develop a methodology that implicitly communicates a region of interest from a helmet-mounted depth camera on the human's head to the robot and an information gain-based exploration objective that biases motion planning within the viewpoint provided by the human. The result is an aerial system that safely accesses regions of interest that may not be immediately viewable or reachable by the human. The approach is evaluated in simulation and with hardware experiments in a motion capture arena. Videos of the simulation and hardware experiments are available at: https://youtu.be/7jgkBpVFIoE.
Rhodium-Catalyzed Intramolecular [4 + 2] Cycloadditions of Alkynyl Halides (2005)

[reaction: see text] Cationic rhodium(I)-catalyzed intramolecular [4 + 2] cycloadditions of diene-tethered alkynyl halides were found to occur in good yields (70-87%). The halide moiety is compatible with the cycloaddition reactions, and no oxidative insertion to the alkynyl halide was observed. The halogen-containing cycloadducts could be transformed into a variety of products that are difficult or impossible to obtain via direct cycloaddition.
ChemInform Abstract: COMPOSITION AND PROPERTIES OF OLIGOMETHYL‐Γ‐TRIFLUOROPROPYLSILOXANES (1978)

Abstract Die Chlorsilane (I)‐(III) werden im Gewichtsverhältnis 2:5 :4 gemischt gemeinsam hydrolysiert und die Hydrolyseprodukte in Gegenwart von Schwefelsäure einer katalytischen Umlagerung unterworfen.
Dosimetry for bioelectromagnetics (2022)

Bioelectromagnetic applications rely on the ability to control the interaction between electromagnetic fields and the body. Designing electrical sensors and medical devices therefore requires the ability to determine the fields in the body that are caused by these devices, or to determine how much the body impacts the fields, creating an image or perturbation that can be received by a device, such as an electrical sensor. Dosimetry is the process of determining these fields, and is the topic of this chapter. Dosimetry requires three major components - a sufficiently precise model of the physical structure of the part(s) of the body the fields will traverse, a model of the electrical properties of these structures, and a numerical method to compute the fields within this model. We will cover all of these topics in this chapter, with a focus on the use of the finite-difference time-domain (FDTD) method for bioelectromagnetic simulations.