gebhart/patrepeval huggingface dataset:
KinÊtre (2012)

KinÊtre allows novice users to scan arbitrary physical objects and bring them to life in seconds. The fully interactive system allows diverse static meshes to be animated using the entire human body. Traditionally, the process of mesh animation is laborious and requires domain expertise, with rigging specified manually by an artist when designing the character. KinÊtre makes creating animations a more playful activity, conducted by novice users interactively "at runtime". This paper describes the KinÊtre system in full, highlighting key technical contributions and demonstrating many examples of users animating meshes of varying shapes and sizes. These include non-humanoid meshes and incomplete surfaces produced by 3D scanning - two challenging scenarios for existing mesh animation systems. Rather than targeting professional CG animators, KinÊtre is intended to bring mesh animation to a new audience of novice users. We demonstrate potential uses of our system for interactive storytelling and new forms of physical gaming.
Cardiac Magnetic Resonance–Derived Extracellular Volume Mapping for the Quantification of Hepatic and Splenic Amyloid (2021)

Our study demonstrates that ECV measurements obtained during routine cardiac magnetic resonance scans in patients with suspected amyloidosis can identify and measure the magnitude of amyloid infiltration in the liver and spleen, providing important clues to amyloid type and offering a noninvasive measure of visceral amyloid burden that can help guide and track treatment.
Studies on Trypsin Activation of Inactive Renin in Rat Plasma (1982)

The experimental conditions of trypsin activation of inactive renin in rat plasma have been studied. Our results showed that the pH optimum of trypsin-activated renin is 6.2, the same as that of rat plasma active renin. Trypsin concentration and incubation time might also interfere with the activation process. Trypsin concentration below 2 mg/ml cannot activate inactive renin. Trypsin at a concentration of 6 mg/ml for 1 min. can cleave dialyzable fragments from renin substrate which can generate Angiotensin I at 37 degrees C with a pH optimum of 5.3 but which do not affect Angiotensin generation at pH 6.2. Longer incubations (more than 2 min.), on the contrary, can produce a cleavage at 4 degrees C of Angiotensin I containing fragments directly from renin substrate strongly interfering with measurements of renin activity at pH 6.2. Trypsin concentrations lower than endogenous rat plasma anti-trypsin activity do not activate inactive renin. Much higher concentrations of trypsin, however, are needed to obtain optimum activation of inactive renin. In average, 40% of the total circulating renin in rat plasma can be activated by trypsin.
Health education—whose responsibility? (1981)

Health education—whose responsibility? Get access Sue Holland, Sue Holland King's Health District (Teaching) Search for other works by this author on: Oxford Academic PubMed Google Scholar Vivienne Speller Vivienne Speller King's Health District (Teaching) Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Public Health, Volume 3, Issue 4, November 1981, Pages 339–340, https://doi.org/10.1093/oxfordjournals.pubmed.a043474 Published: 01 November 1981
Laser acceleration of protons with an optically shaped, near-critical hydrogen gas target (2017)

We report our recent experimental results on CO2 laser acceleration of protons, with a near-critical hydrogen gas target tailored by a Nd:YAG laser-produced blast wave. Monoenergetic protons with energies up to 2.5 MeV were observed.
Supramolecular P4VP-pentadecylphenol naphthalenebisimide comb-polymer: mesoscopic organization and charge transport properties (2014)

A supramolecular comb polymer complex of unsymmetric naphthalenebisimide with poly(4-vinyl pyridine) <italic>via</italic> hydrogen bonding – <bold>P4VP(PDP-UNBI)n</bold> – led to highly ordered layered assembly with improved nanoscale packing of the semiconductor moieties and improved electron mobilities.
Joystick Haptic Force Feedback for Powered Wheelchair - A Model-based Shared Control Approach (2020)

This paper proposes a novel approach for designing an assistance system via haptic joystick force feedback on an electric wheelchair using model-based shared control approach. Assistance system supports wheelchair users through haptic force at joystick which can make the user-wheelchair interaction becomes more intuitive. Firstly Tagaki-Sugeno fuzzy model is used to build an augmented model of user-wheelchair system to deal with non-linear nature of system. Unknown input observers are developed to estimate wheelchair position errors which are considered as user intention based on joystick motions. Fuzzy logic optimal controller is synthesized by Linear Matrix Inequalities method to provide assistance haptic forces feedback to user via joystick. Simulation and experimental results show that this assistance system can predict the desired motion of user and reduce user hand force thanks to haptic force at joystick.
Cryptosporidiosis among patients with the acquired immunodeficiency syndrome in Maracaibo, Venezuela (1991)

Cryptosporidium is a coccidian parasite found in the intestinal and respiratory epithelia of a wide variety of vertebrate hosts. First reported in 1976 cryptosporidiosis among humans has increased dramatically since 1982. Cryptosporidium has now become one of the most common intestinal protozoa and one of the most frequent opportunistic infections in AIDS patients. Infection causes only self-limited diarrheal illness in immunocompetent persons but severe sometimes life-threatening and protracted diarrhea in immunosuppressed persons. Large-scale surveys of selected populations have found infection prevalence rates of 0.6-20% in developed countries and 4-20% in developing countries. There is however little information about cryptosporidiosis in Venezuela. The authors report findings from a preliminary study designed to evaluate the prevalence and clinical significance of Cryptosporidium in patients with AIDS in Maracaibo. Three stool specimens were collected from each of seven male and three female symptomatic patients. All were residents of Maracaibo aged 7-35 years. All had mild or severe diarrhea and some had one or more of the following manifestations: abdominal pain malaise weight loss cough with expectoration lymphadenopathy candidiasis and herpes. Four patients had Cryptosporidium oocysts associated with Trichuris trichiura and Blastocystis hominis in one case while two had only Giardia lamblia trophozoites. All cases infected with Cryptosporidium presented an inflammatory exudate replete with leukocytes plasma cells and macrophages; two cases had Charcot-Leyden crystals. This frequency of infection with Cryptosporidium is higher than that observed in the US and Brazil and similar to the frequencies reported from Africa and Haiti. The authors note that the main symptom of cryptosporidiosis is a non-inflammatory diarrhea with leukocytes rarely seen. The inflammatory exudate with abundant leukocytes observed in all of these infected patients however suggests the involvement of other associated enteropathogens and warrants further investigation.
Large Eddy Simulation and CO Prediction of Reheat Burner Switch-Off Concept (2015)

The reduction of the Minimum Environmental Load (MEL) is a key requirement for increased operational flexibility of Combined Cycle Power Plants (CCPP). In reheat combustors, the MEL is in general limited by CO emissions. The sequential combustion system used in Alstom GT24/GT26 gas turbines [1, 2] offers a unique operation concept, namely Low Part Load operation concept with switched off SEV burner (LPL). This concept is able to significantly reduce CO and thus MEL. Details of the CO formation mechanisms for this concept are analyzed via unsteady CFD calculations. These results are used to predict CO emissions for the full engine. Results are validated against experiments on full engine scale. Field implementation of the LPL concept and validation experience collected during long term commercial operation is described in a separate paper [4].
Emotion recognition using dynamic grid-based HoG features (2011)

Automatic facial expression analysis is the most commonly studied aspect of behavior understanding and human-computer interface. The main difficulty with facial emotion recognition system is to implement general expression models. The same facial expression may vary differently across humans; this can be true even for the same person when the expression is displayed in different contexts. These factors present a significant challenge for the recognition task. The method we applied, which is reminiscent of the “baseline method”, utilizes dynamic dense appearance descriptors and statistical machine learning techniques. Histograms of oriented gradients (HoG) are used to extract the appearance features by accumulating the gradient magnitudes for a set of orientations in 1-D histograms defined over a size-adaptive dense grid, and Support Vector Machines with Radial Basis Function kernels are the base learners of emotions. The overall classification performance of the emotion detection reached 70% which is better than the 56% accuracy achieved by the “baseline method” presented by the challenge organizers.
Orthogonal Ham-Sandwich Theorem in ℝ3 (2010)

The ham-sandwich theorem states that, given d ≥ 2 measures in ℝd, it is possible to divide all of them in half with a single (d – 1)-dimensional hyperplane. We study an orthogonal version of the ham-sandwich theorem and define an orthogonal cut using at most d hyperplanes orthogonal to coordinate axes. For example, a hyperplane orthogonal to a coordinate axis and the boundary of an orthant are orthogonal cuts. We prove that any three measures in ℝ3 can be divided in half each with a single orthogonal cut. Applied to point measures, it implies that any three finite sets of points in ℝ3 can be simultaneously bisected by an orthogonal cut. We present an algorithm for computing an orthogonal ham-sandwich cut in O(n log n) time.
ChemInform Abstract: STUDIES OF ELECTROCHEMICAL INTERFACES OF THIN PT FILM ELECTRODES BY SURFACE CONDUCTANCE (1975)

Abstract Die Gleichstromleitfähigkeit dünner Pt‐Filme wird zur Bestimmung der Filmdicke und der Oberflächeneffekte in Abhängigkeit vom Elektrodenpotential in der "idealen" Doppelschicht und in Platin‐Sauerstoff‐ sowie Wasserstoffadsorptionsbereichen gemessen.
Neuropeptidases, Stress, and Memory—A Promising Perspective (2016)

Stress has been demonstrated to be a key modulator in learning and memory processes, in which the hippocampus plays a central role. A great number of neuropeptides have been reported to modulate learning and memory under stressful conditions. Neuropeptidases are proteolytic enzymes capable of regulating the function of neuropeptides in the central and peripheral nervous system. In this regard, a number of neuropeptidases, i.e. angiotensinases, oxytocinase, or enkephalinases, have received attention. Their involvement in stress and memory processes is a promising perspective, as it is possible to influence their activities through various activators or inhibitors and, consequently, to pharmacologically modulate the functions of the endogenous substrates that are involved. The present review describes the key findings showing the involvement of neuropeptides and neuropeptidases in stress and memory and highlights the role of the hippocampus in these processes.
Experimentation on Virtualized Routing Function Migration Using OpenFlow (2013)

[ANGLES] Network Function Virtualization has emerged as an operator proposal for offering network services with network functions implemented in software, which may be located in Data Centers, network nodes or even in a virtual machine. NFV is theoretically applicable to any network function and aims at simplifying the management of heterogeneous hardware platforms. Using as a basis one of the network functions offered by network routers, this thesis presents the analysis, design, and the first implementation, in a virtualized manner, of the routing function. Considering the current co-existence of IPv4 and IPv6 and the possibilities brought into the arena by OpenFlow-enabled infrastructures, the thesis describes the design of the virtualized routing protocol, enabling a simple management and avoiding signaling messages overhead in the control plane level, and the different scenarios considered to validate the virtualized function. In essence, the thesis describes one of the first implementations of the functional NFV concept, through the virtualization of the routing function over an OpenFlow network. The different scenarios validated in this thesis are used to demonstrate the applicability of the NFV-powered implementation proposed into actual production environments.
Three antigen-loading methods in dendritic cell vaccines for metastatic melanoma (2018)

In the current era of checkpoint inhibitors, some patients with metastatic melanoma have shown a significant improvement in survival. However, optimization of immunotherapy is an ongoing effort. Monocyte-derived dendritic cell (MODC) vaccines have been shown in clinical trials to be safe and capable of inducing tumor-specific immunity as well as occasional objective clinical responses. Here, we conducted a three-arm pilot clinical study in 15 patients with metastatic melanoma to evaluate three types of MODC vaccines, differing only by strategies of tumor antigen delivery. MODCs were isolated from each patient and loaded with patients' own melanoma cells as sources of antigens. Antigen loading was achieved ex vivo by fusing melanoma cells with MODCs, co-culturing melanoma cells with MODCs, or by pulsing MODCs with melanoma cell lysates. The vaccines were then injected into superficial lymph nodes using high-resolution ultrasound guidance. Primary end points included delayed-type hypersensitivity responses and positive ELISpot result, which measures interferon-γ production. Five of 15 patients achieved delayed-type hypersensitivity responses and six of 15 patients had positive ELISpot results. We demonstrated that the vaccines were safe and well-tolerated by all patients and produced immunological responses in all arms. Although MODC vaccine monotherapy has limited efficacy, combining this vaccine with other immunotherapies, such as checkpoint inhibitors, to engage multiple components of the immune system may be an effective and viable future approach.
ChemInform Abstract: Six New Antimicrobial and Nematicidal Bisabolanes from the Basidiomycete Cheimonophyllum candidissimum. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Well defined block copolymers of ε‐caprolactone and L‐lactide using Y5(μ‐O)(OiPr)13 as an initiator (1995)

Abstract Diblock copolymers composed of poly(ε‐caprolactone) and poly(L‐lactide) were synthesized via sequential living ring‐opening polymerization of ε‐caprolactone and L‐lactide in dichloromethane initiated by Y 5 (μ‐O)(O i Pr) 13 (yttrium isopropoxide). A series of diblock copolymers was synthesized with ε‐caprolactone blocks of constant length (DP = 70) and lactide blocks of varying length (DP = 5–80), with polydispersities of 1,18–1,27. Molecular weights were close to theoretical values. 13 C NMR spectroscopy shows the absence of transesterification reactions and racemization. The thermal properties of the block copolymers were studied using differential scanning calorimetry. The block copolymers show a certain degree of phase mixing depending on the length of the poly(L‐lactide) blocks. Crystallization of L‐lactide sequences did not occur when the block length consisted of less than 40 L‐lactic acid residues.
Internucleosomal Deoxyribonucleic Acid Cleavage Activity in Apoptotic Thymocytes: Detection and Endocrine Regulation* (1991)

Apoptosis is a programmed form of cell death that occurs under numerous physiological conditions, including endocrine regulation of specific cell populations. We have investigated the biochemical mechanisms involved in glucocorticoid-induced apoptosis in rat thymocytes. Internucleosomal cleavage of chromatin into oligonucleosomal fragments is common to all forms of apoptosis and precedes the onset of cell death. To identify the endonuclease that is responsible for the specific pattern of DNA degradation in glucocorticoid-induced apoptosis, we have developed an assay to measure internucleosomal cleavage activity in thymocyte nuclear extracts. This assay uses nuclei from cells resistant to hormone-induced DNA fragmentation (HeLa cells) as a substrate for nuclear extracts prepared from thymocytes of adrenalectomized rats treated with either dexamethasone (dex) or vehicle (control). After incubation at room temperature for 90 min, the HeLa DNA is purified, and its integrity is analyzed by agarose gel electrophoresis. The appearance of internucleosomal fragments of HeLa DNA is indicative of nuclease activity in the thymocyte nuclear extract. Nuclear extracts prepared from thymocytes of rats treated with dex for 5 h caused internucleosomal cleavage of HeLa DNA, whereas extracts from control rats did not result in any DNA fragmentation. Regulation of nuclease activity by dex was time dependent. Internucleosomal cleavage activity in thymocyte extract from dex-treated animals was detected as early as 2 h after hormone treatment and occurred before any detectable change in cell viability. Maximal extractable nuclease activity was coincident with decreased thymocyte viability and thymic involution. In contrast, extracts from medullary thymocytes, which are the only thymocytes that survive 72 h of glucocorticoid treatment, did not contain nuclease activity by this assay. Regulation of internucleosomal cleavage activity by dex was dose dependent and was specific for the glucocorticoid class of steroid hormones. Furthermore, the dex-induced response was inhibited by pretreating rats with the glucocorticoid receptor antagonist RU486, indicating that receptor-mediated processes are involved in the regulation of nuclease activity. The similarities between the regulation of internucleosomal cleavage activity reported here and the previously described degradation of thymocyte DNA in vivo makes this nuclease a likely constituent of the apoptotic process.
Weakly-Supervised Open-Retrieval Conversational Question Answering (2021)

Recent studies on Question Answering (QA) and Conversational QA (ConvQA) emphasize the role of retrieval: a system first retrieves evidence from a large collection and then extracts answers. This open-retrieval ConvQA setting typically assumes that each question is answerable by a single span of text within a particular passage (a span answer). The supervision signal is thus derived from whether or not the system can recover an exact match of this ground-truth answer span from the retrieved passages. This method is referred to as span-match weak supervision. However, information-seeking conversations are challenging for this span-match method since long answers, especially freeform answers, are not necessarily strict spans of any passage. Therefore, we introduce a learned weak supervision approach that can identify a paraphrased span of the known answer in a passage. Our experiments on QuAC and CoQA datasets show that the span-match weak supervisor can only handle conversations with span answers, and has less satisfactory results for freeform answers generated by people. Our method is more flexible as it can handle both span answers and freeform answers. Moreover, our method can be more powerful when combined with the span-match method which shows it is complementary to the span-match method. We also conduct in-depth analyses to show more insights on open-retrieval ConvQA under a weak supervision setting.
Desorption Behavior of Sorbed Flavor Compounds from Packaging Films with Ethanol Solution (2000)

Desorption behavior of sorbed flavor compounds such as ethyl esters, n-aldehydes, and n-alcohols from LDPE and PET films was investigated in 0 to 100% (v/v) ethanol solutions at 20 degrees C, 50 degrees C, and 60 degrees C. In both films, the desorption apparently increased with increasing ethanol concentration and treatment temperature, depending on the compatibility of the flavor compound with the solvent. Namely, the partition coefficient of ethyl esters, n-aldehydes, and n-alcohols in the LDPE film turned out to be approximately zero at >/=60%, >/=80%, and >/=40% (v/v) ethanol, respectively (for PET film, >/=80%, >/=80%, and >/=40% (v/v) ethanol concentrations were required for complete desorption, respectively). As for physical properties (heat of fusion, melting point, and tensile strength and elongation at break) of LDPE and PET films, there were no significant differences between intact film and the treated film with 60% (v/v) ethanol for 30 min at 60 degrees C. These results suggest that it is possible to apply a desorption solvent such as ethanol solution for desorption of sorbed flavor compounds from packaging films with no physical change in the film properties by this desorption treatment.
Establishment and characterization of 7 ovarian carcinoma cell lines and one granulosa tumor cell line: Growth features and cytogenetics (1993)

The characteristics of 7 newly established ovarian carcinoma cell lines and one granulosa tumor cell line obtained from tumor samples of 7 patients with varying histology of the primary tumor are reported. The cell lines were isolated from 5 serous carcinomas, a mucinous carcinoma, an endometrioid carcinoma and a granulosa cell tumor. All cell lines were passaged at least 25 times and showed stable growth rates. Colony-forming efficiency varied on plastic from 2 to 57% and in agar from 0.01 to 9.30%. The DNA index of the granulosa tumor cell line was diploid, while the ovarian carcinoma cell lines were all aneuploid. In 2 cell lines polyploidisation occurred during culturing. A thorough cytogenetic analysis of 7 cell lines revealed that the granulosa tumor cell line has only minor cytogenetic abnormalities (+5, 22q+). In contrast, the epithelial ovarian-cancer cell lines gave very complex karyotypes with numerous markers and structurally rearranged chromosomes. The chromosomes most often in excess were 15 and 20. Structural rearrangements of chromosomes 1, 3, 7 and 11 were prominent in all ovarian cell lines. In addition, we found changes in chromosomes X, 5, 8 and 13 that have rarely been described before.
Effect of gliadin and other food peptides on expression of MHC class II molecules by HT-29 cells. (1995)

Expression of major histocompatibility (MHC) class II molecules by enterocytes is known to be enhanced in coeliac disease and other disorders characterised by intestinal inflammation--an effect thought to be mediated via intestinal lymphocytes. To investigate if food peptides can exert direct effects on class II expression, the influence of gliadins, casein, and beta lactoglobulin on an intestinal epithelial cell line (HT-29) was examined in the absence of immune cells. Class II expression was determined by flow cytometry and immunofluorescence microscopy using antibodies against the beta chain of all products of the gene subregions DR, DQ, and DP. MHC expression was low in HT-29 cells but could be stimulated by interferon gamma. Tryptin digested gliadin had no effect on class II expression. In the presence of interferon gamma, however, it was able to amplify MHC class II expression to mean (SEM) 150 (4)%. Casein exerted a similar effect (160 (14)%), but undigested gliadin, tryptin digested casein, and beta lactoglobulin had no influence. The observations suggest that within the concert of cytokine mediated interactions between enterocytes and lymphocytes, some dietary peptides could upregulate the presentation of food antigens, leading to a more efficient stimulation of lymphocytes, which in the case of coeliac disease might result in damage to the enterocytes.