gebhart/patrepeval huggingface dataset:
Numerical simulation of active control of boundary layer transition (1988)

Abstract : A numerical model has been developed for investigating boundary layer transition control for a two-dimensional flat plate boundary layer. Control of a periodically forced boundary layer in an incompressible fluid is studied using surface heating techniques. The spatially evolving boundary layer is simulated. Navier-Stokes and energy equations are integrated using a fully implicit finite difference/spectral method. The Navier-Stokes equations are in vorticity- velocity form and are coupled with the energy equation through the viscosity dependence on temperature. Both passive and active methods of control by surface heating are investigated. In passive control methods, wall heating is employed to alter the stability characteristics of the mean flow. Both uniform and nonuniform surface temperature distributions are studied. With active control, temperature perturbations are introduced locally along finite heater strips to directly attenuate the instability waves in the flow. A feedback control loop is employed in which a downstream sensor is used to monitor wall shear stress fluctuations. Passive control of small amplitude two-dimensional Tollmien- Schlichting waves and three-dimensional oblique waves are numerically simulated with both uniform and nonuniform passive heating applied. Strong reductions in both amplitude levels and amplification rates are achieved. Active control of small amplitude two-dimensional and three-dimensional disturbances is also numerically simulated. With proper phase control, in phase reinforcement and out of phase attenuation is demonstrated. (KR)
A role for the immune system in advanced laryngeal cancer (2020)

To investigate the role of the altered activation of the immune system in the prognosis of patients affected by laryngeal squamous cell carcinoma (LSCC). We analyzed 56 patients with advanced LSCC divided into two groups according to their prognosis: the first group relapsed within 24 months after treatment, the second group had no evidence of disease at 2 years. The presence of stromal tumor infiltrating lymphocytes (TILs) at the tumor-host border was investigated. In 43 patients we evaluated the expression of 395 genes related to immune system activation through a next generation sequencing panel. Priority-LASSO models and clustering analyses were integrated with multivariate Cox proportional hazard modeling to identify independent genes associated with relapse and estimate hazard ratios in relation to gene expression and TILs. TILs and the expression of genes related with immune system activation (FCGR1A, IFNA17, FCRLA, NCR3, KREMEN1, CD14, CD3G, CD19, CD20 and CD79A) were significantly associated with prognostic factors or disease specific survival. In patients with lymph node metastases and advanced T stage (pT4), the expression of other genes was altered. Low TILs count was highly associated with relapse within 2 years (p < 0.001). Low TILs and altered expression of specific genes associated with tumor-immune systems interactions emerged as independent risk factors, associated to poor prognosis and relapse within 2 years in advanced LSCC. Evaluation of patients' immune profile could be useful for prognosis and future therapeutic approaches towards personalized therapy.
Single-layer graphene-assembled 3D porous carbon composites with PVA and Fe3O4 nano-fillers: an interface-mediated superior dielectric and EMI shielding performance (2015)

In this study, a novel composite of Fe3O4 nanofiller-decorated single-layer graphene-assembled porous carbon (SLGAPC) with polyvinyl alcohol (PVA) having flexibility and a density of 0.75 g cm(-3) is explored for its dielectric and electromagnetic interference (EMI) response properties. The composite is prepared by the solution casting method and its constituents are optimized as 15 wt% SLGAPC and 20 wt% Fe3O4 through a novel solvent relaxation nuclear magnetic resonance experiment. The PVA-SLGAPC-Fe3O4 composite shows high dielectric permittivity in the range of 1 Hz-10 MHz, enhanced by a factor of 4 as compared to that of the PVA-SLGAPC composite, with a reduced loss by a factor of 2. The temperature dependent dielectric properties reveal the activation energy behaviour with reference to the glass transition temperature (80 °C) of PVA. The dielectric hysteresis with the temperature cycle reveals a remnant polarization. The enhanced dielectric properties are suggested to be the result of improvement in the localized polarization of the integrated interface system (Maxwell-Wagner-Sillars (MWS) polarization) formed by the uniform adsorption of Fe3O4 on the surface of SLGAPC conjugated with PVA. The EMI shielding property of the composite with a low thickness of 0.3 mm in the X-band (8.2-12.4 GHz) shows a very impressive shielding efficiency of ∼15 dB and a specific shielding effectiveness of 20 dB (g cm(-3))(-1), indicating the promising character of this material for flexible EMI shielding applications.
Subpixel location of discrete target images in close-range camera calibration: a novel approach (2007)

A novel approach is presented for the location of discrete targets images with subpixel accuracy. It can be adopted as first stage of any method that uses planar and no-planar grids with circular, square or cross shaped targets in order to calibrate close range cameras. The approach has been performed on several calibration sessions each of them followed by the three-dimensional reconstruction of a reference object that was previously measured through a coordinate measuring machine. The performance of the proposed approach has been expressed in terms of deviation between the reference coordinates and the corresponding ones provided by triangulation. The results obtained have also been compared with those achieved through ShapeCapture<sup>TM</sup>, a software widely used in photogrammetry for camera calibration and 3D model reconstruction from images.
Abstract 15275: Non Val30met Mutation, Septal Hypertrophy and Delayed Heart/Mediastium Ratio Are Useful Predictors of Poor Clinical Outcome in Japanese Patients With Hereditary Transthyretin Amyloidosis (2017)

Introduction: Hereditary transthyretin amyloidosis (ATTRm) often causes cardiac amyloidosis, and cardiac involvements worsen clinical outcome. However, there is little information about predictor o...
Method of intraoperative spectroscopic detection of tumor tissues in neurosurgery (2018)

The proposed method provides neurosurgical intraoperative navigation using optical spectroscopy and neurophysiological stimulation. The device contains a spectrometer, sources of optical radiation and fiber-optic probe, the working part of which is made in one body with a cannula of neurosurgical aspirator and can be used also as a monopolar stimulant for the system of intraoperative neuromonitoring.
RIGOROUS PROOF FOR CHARACTERISTICS OF PRACTICABLE MAGNETIC POTENTIOMETERS ND THEIR APPLICATION (2001)

The characters of practicable magnetic potentiometers have not been rigorously proved. This paper deduced a mathematical description of mutual inductance of the cylindricalmagneticpotentiometerwithfinite turns crosssection and verifies that M is independent of the position with respect to the primary circuit and is unaffected by stray fields of current not linked with them. Using these features, a novel device is designed to measure ACcurrent of the measuring range 0~4 000 A. The experimental result shows the measuring error is less than 1%.The device holds various advantages: such as the fixed number of turns of the primary winding, low cost, small size and weight. This paper pointed out that if the device is used to measure the nonsinusoidal signal, an integrator can increase the accuracy.
INVESTIGATIONS ON THE EFFECTS OF 2,3,7,8‐TETRACHLORODIBENZO‐p‐DIOXIN (TCDD) ON PARAMETERS OF VARIOUS IMMUNE FUNCTIONS (1979)

The effects of TCDD exposure on parameters of immune function during the developmental period were investigated. Exposures were performed in Fischer/Wistar rats. Fetal and neonatal rats were exposed to TCDD through maternal dosing (5 micrograms/Kg) on day 18 of gestation and on days 0, 7, and 14 of postnatal life (group 1). Another group of neonatal rats were exposed to TCDD through maternal dosing on days 0, 7, and 14 of postnatal life only (group 2). Body weights and relative thymus weights were found to be suppressed up to 135 days of age in group 1 but only up to 35 days of age in group 2. Parameters of cell-mediated and humoral immune function were investigated. TCDD suppressed cell-mediated immune function without affecting humoral immune function. TCDD-exposed animals had recovered normal cell-mediated immune function by 270 days of age. A group of inbred Fischer rats was exposed to TCDD as described for group 1 above. At 45 days of age these animals were utilized in lymphocyte homing studies. It was found that TCDD exposure alters homing patterns of lymphocytes from exposed animals when adoptively transferred to untreated animals. In addition, lymphocytes from nonexposed animals did not home normally when injected into TCDD-exposed recipients.
Lithium salts as “redox active” p-type dopants for organic semiconductors and their impact in solid-state dye-sensitized solar cells (2012)

Lithium salts have been shown to dramatically increase the conductivity in a broad range of polymeric and small molecule organic semiconductors (OSs). Here we demonstrate and identify the mechanism by which Li+ p-dopes OSs in the presence of oxygen. After we established the lithium doping mechanism, we re-evaluate the role of lithium bis(trifluoromethylsulfonyl)-imide (Li-TFSI) in 2,2′,7,7′-tetrakis(N,N-di-p-methoxyphenyl-amine)9,9′-Spirobifluorene (Spiro-OMeTAD) based solid-state dye-sensitized solar cells (ss-DSSCs). The doping mechanism consumes Li+ during the device operation, which poses a problem, since the lithium salt is required at the dye-sensitized heterojunction to enhance charge generation. This compromise highlights that new additives are required to maximize the performance and the long-term stability of ss-DSSCs.
Transcriptome and Proteome Analysis Revealed the Influence of High-Molecular-Weight Glutenin Subunits (HMW-GSs) Deficiency on Expression of Storage Substances and the Potential Regulatory Mechanism of HMW-GSs (2023)

The processing quality of wheat is affected by seed storage substances, such as protein and starch. High-molecular-weight glutenin subunits (HMW-GSs) are the major components of wheat seed storage proteins (SSPs); they are also key determinators of wheat end-use quality. However, the effects of HMW-GSs absence on the expression of other storage substances and the regulation mechanism of HMW-GSs are still limited. Previously, a wheat transgenic line LH-11 with complete deletions of HMW-GSs was obtained through introducing an exogenous gene <i>Glu-1E<sup>b</sup>x</i> to the wild-type cultivar Bobwhite by transgenic approach. In this study, comparative seed transcriptomics and proteomics of transgenic and non-transgenic lines at different seed developmental stages were carried out to explore the changes in genes and proteins and the underlying regulatory mechanism. Results revealed that a number of genes, including genes related to SSPs, carbohydrates metabolism, amino acids metabolism, transcription, translation, and protein process were differentially enriched. Seed storage proteins displayed differential expression patterns between the transgenic and non-transgenic line, a major rise in the expression levels of gliadins were observed at 21 and 28 days post anthesis (DPA) in the transgenic line. Changes in expressions of low-molecular-weight glutenins (LMW-GSs), avenin-like proteins (ALPs), lipid transfer proteins (LTPs), and protease inhibitors (PIs) were also observed. In addition, genes related to carbohydrate metabolism were differentially expressed, which probably leads to a difference in starch component and deposition. A list of gene categories participating in the accumulation of SSPs was proposed according to the transcriptome and proteome data. Six genes from the MYB and eight genes from the NAC transcription families are likely important regulators of HMW-GSs accumulation. This study will provide data support for understanding the regulatory network of wheat storage substances. The screened candidate genes can lay a foundation for further research on the regulation mechanism of HMW-GSs.
ChemInform Abstract: SYNTHESIS OF OXAZAPHOSPHORINANES BASED ON N‐METHYLANTHRANILIC ACID (1985)

Abstract N‐Methylanthranilsäure (I) wird in das Chlorid (II) übergeführt.
Spin-based quantum computing in silicon (2015)

This talk will review recent progress in the development of spin qubits in silicon. In particular it will consider qubit systems based on single phosphorus atoms, in which either the bound donor electron or the 31P nuclear spin can serve as a qubit, and also silicon metal-oxide-semiconductor (SiMOS) quantum dots within which single confined electrons can act as a qubit. In both cases the qubit control fidelity can be above above 99%, as required for some quantum error correction codes.
Relationship Discovery with NetFlow to Enable Business-Driven IT Management (2006)

The understanding of relationships and dependencies between business processes and the underlying IT infrastructure is important for enabling business-driven IT management. This work uses the widespread NetFlow feature to derive direct and indirect traffic relationships in IT infrastructures. We define an algorithm for relationship discovery with NetFlow and describe the application of the discovery approach in a large production environment.
Morphology and Interface of Liquid Crystal/Polymer Composite System at Nano Scale :A Model Investigation (1999)

Abstract Morphology of the liquid crystal/polymer composite has been investigated at the microscopic level as a model investigation in order to elucidate the nature of microscopic phase separation. It has been observed that the modification of surface interaction between liquid crystal and polymer is different for different system, which is apparent from the nature of phase separation at microscopic scale.
Dielectric elastomers: generator mode fundamentals and applications (2001)

Dielectric elastomers have shown great promise as actuator materials. Their advantages in converting mechanical to electrical energy in a generator mode are less well known. If a low voltage charge is placed on a stretched elastomer prior to contraction, the contraction works against the electrostatic field pressure and raises the voltage of the charge, thus generating electrical energy. This paper discusses the fundamentals of dielectric elastomer generators, experimental verification of the phenomenon, practical issues, and potential applications. Acrylic elastomers have demonstrated an estimated 0.4 J/g specific energy density, greater than that of piezoelectric materials. Much higher energy densities, over 1 J/g, are predicted. Conversion efficiency can also be high, theoretically up to 80-90%; the paper discusses the operating conditions and materials required for high efficiency. Practical considerations may limit the specific outputs and efficiencies of dielectric elastomeric generators, tradeoffs between electronics and generator material performance are discussed. Lastly, the paper describes work on potential applications such as an ongoing effort to develop a boot generator based on dielectric elastomers, as well as other applications such as conventional power generators, backpack generators, and wave power applications.
The effectiveness of footwear and offloading interventions to prevent and heal foot ulcers and reduce plantar pressure in diabetes: a systematic review (2008)

This systematic review provides support for the use of non-removable devices for healing plantar foot ulcers. Furthermore, more high-quality studies are urgently needed to confirm the promising effects found in both controlled and uncontrolled studies of footwear and offloading interventions designed to prevent ulcers, heal ulcers, or reduce plantar pressure.
The African Economic Community: Problems and Prospects (1995)

The shikimate pathway links metabolism of carbohydrates to biosynthesis of aromatic compounds. In a sequence of seven metabolic steps, phosphoenolpyruvate and erythrose 4-phosphate are converted to chorismate, the precursor of the aromatic amino acids and many aromatic secondary metabolites. All pathway intermediates can also be considered branch point compounds that may serve as substrates for other metabolic pathways. The shikimate pathway is found only in microorganisms and plants, never in animals. All enzymes of this pathway have been obtained in pure form from prokaryotic and eukaryotic sources and their respective DNAs have been characterized from several organisms. The cDNAs of higher plants encode proteins with amino terminal signal sequences for plastid import, suggesting that plastids are the exclusive locale for chorismate biosynthesis. In microorganisms, the shikimate pathway is regulated by feedback inhibition and by repression of the first enzyme. In higher plants, no physiological feedback inhibitor has been identified, suggesting that pathway regulation may occur exclusively at the genetic level. This difference between microorganisms and plants is reflected in the unusually large variation in the primary structures of the respective first enzymes. Several of the pathway enzymes occur in isoenzymic forms whose expression varies with changing environmental conditions and, within the plant, from organ to organ. The penultimate enzyme of the pathway is the sole target for the herbicide glyphosate. Glyphosate-tolerant transgenic plants are at the core of novel weed control systems for several crop plants.
ODAR: On-Demand Anonymous Routing in Ad Hoc Networks (2006)

Routing in wireless ad hoc networks are vulnerable to traffic analysis, spoofing and denial of service attacks due to open wireless medium communications. Anonymity mechanisms in ad hoc networks are critical security measures used to mitigate these problems by concealing identification information, such as those of nodes, links, traffic flows, paths and network topology information from harmful attackers. We propose ODAR, an On-Demand Anonymous Routing protocol for wireless ad hoc networks to enable complete anonymity of nodes, links and source-routing paths/trees using Bloom filters. We simulate ODAR using J-Sim, and compare its performance with AODV in certain ad hoc network scenarios
2D-Qsar for 450 types of amino acid induction peptides with a novel substructure pair descriptor having wider scope (2011)

QSAR/QSPR for peptides is helpful for designing various types of drugs such as kinase inhibitor and antigen. SPAD is a novel and powerful descriptor for various types of peptides. Accuracy of QSAR/QSPR becomes higher by describing peptides with SPAD.
Development of SiC ultra light mirror for large space telescope and for extremely huge ground-based telescope (2003)

Ultra lightweight mirrors of silicon carbide (SiC) are used for a large number of space telescopes, and SiC is also candidate as hopeful material for segmented mirrors of the next generation ground based telescopes from 20 to 100 m in diameter. However, an SiC mirror is difficult to shape because the material is very hard and brittle. We are developing an SiC mirror by means of an ultra-precision rotary grinding machine (800 mm in diameter) and the ELID (ELectrolytic In-process Dressing) grinding method. The method is suitable for fabrications of very hard materials, such as crystalline silicon and sapphire, ceramics, glasses, hard metals and so on. In this study, we present results of test fabrication for the SiC mirrors by means of ELID grinding method and evaluations of the profile deformation of the lightweight mirrors by using FEM simulation method.
Abstract 13080: Myocardial G Protein-Coupled Receptor Kinase 5 Contributes to Impaired Cardiac Function and Immune Cell Recruitment in Ischemic Heart Failure (2019)

Introduction: Myocardial ischemia (MI) is the most common cause of heart failure (HF) in the United States. G protein-coupled receptor (GPCR) kinase 5 (GRK5) has been found to be upregulated in fai...
ChemInform Abstract: Synthesis and Antifungal Activities of (2R,3R)‐2‐Aryl‐1‐azolyl‐3‐(substituted amino)‐2‐butanol Derivatives as Topical Antifungal Agents. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Caractérisation de céramiques massives et de couches épaisses préparées à partir des nanopoudres de BaTiO3 (2006)

Des poudres fines de BaTiO3 (BT) sont synthétisées par la méthode hydrothermale ? 250 ?C pendant 7 heures. Deux mélanges précurseurs différents sont utilisés : TiCl3 + BaCl2 et TiO2 + BaCl2. La taille des cristallites résultante est voisine de 20 nm indépendamment du mélange initial. Ces poudres sont alors employées pour préparer des céramiques massives (pastilles) et des couches épaisses déposées sur substrat plan. L'influence des précurseurs et du type de mise en oeuvre est mise en évidence en étudiant la permittivité tant dans le domaine des températures que des fréquences.
Immune tolerance to a defined heterologous antigen after intrasplenic hepatocyte transplantation: implications for gene therapy (1992)

Development of a host immune response against gene products expressed by genetically modified cells could be a serious limitation for gene therapy. During examination of whether site-specific differences in antigen presentation could regulate the host immune response, we observed an absence of antibodies against hepatitis B virus surface antigen (HBsAg) when HBsAg producing transgenic hepatocytes were transplanted into the spleen. Intrasplenic transplantation resulted in translocation of a large number of cells into the portal vascular bed and liver sinusoids. In these recipients, HBsAg secreted by the transplanted hepatocytes circulated indefinitely in the blood. In contrast, subcutaneous or intraperitoneal transplantation of the transgenic hepatocytes induced an anti-HBs response, followed by clearance of serum HBsAg. Rechallenge with HBsAg in a highly immunogenic form failed to break the tolerance in intrasplenic hepatocyte recipients even though these animals responded to another antigen (keyhole limpet hemocyanin). Immunization with HBsAg in intraperitoneal recipients of HBsAg producing hepatocytes further elevated anti-HBs titers. Our results indicate that hepatocyte transplantation into the portal vascular bed via injection into the spleen can confer immune tolerance to secreted heterologous antigens. This finding should have important implications for human gene therapy as well as for analyzing the mechanisms of immune tolerance.
NOD2 Loss-of-Function Mutations and Risks of Necrotizing Enterocolitis or Focal Intestinal Perforation in Very Low-birth-weight Infants (2016)

VLBW infants carrying ≥ 2 NOD2 genetic risk factors of inflammatory bowel disease in adults have an increased risk for severe gastrointestinal complications, such as NEC requiring surgery. Therefore, infants might benefit from NOD2 genotyping followed by supplementation with probiotics. Replication studies are needed along with genome-wide arrays to allow risk-adapted prevention and therapeutic strategies.