gebhart/patrepeval huggingface dataset:
Enhanced Receivers for Interference Cancellation in 3G Systems (2015)

Abstract. Interference cancellation and multiuser detec-tion in CDMA systems are still actual research topics. These techniques enable us to deal with interference and to increase system capacity. In this paper, a so-called Gener-alized RAKE receiver, an Uplink generalized multiuser detection and a Blind adaptive multiuser detection are described. These algorithms are compared with conven-tional receivers and their properties are verified via simu-lations. The results imply that some of these algorithms are able to overcome the performance of the conventional receivers.
Particulate and dissolved phytoplankton production of the Patos Lagoon estuary, southern Brazil: comparison of methods and influencing factors (1994)

Uptake rates of 14C (filtration and the acidification-bubbling method—ABM) were measured weekly in a shallow region of the Patos Lagoon estuary (32°07'S, 52°06'W) between March 1989 and March 1990. Phytoplankton production varied seasonally, the lowest values occurring in the austral winter (June–August 1989) and the highest rates during spring and summer (March 1989; September 1989–March 1990). Particulate carbon production varied between 0.65 and 70.6 mg C m−3 h−1 and was mostly associated with organisms <20 μm (mean = 73.4%). Dissolved organic carbon (DOC) released by phytoplankton varied between 0.1 and 89.3 mg C m−3 h−1 representing ∼22% of total (particulate + dissolved) carbon uptake. Production rates estimated by the ABM ranged from 2.2 to 159.4 mg C m−3 h−1 and were equivalent to the sum of particulate and dissolved carbon production, simultaneously determined by the filtration technique. In general, primary production rates related to incident irradiance and water temperature, whilst high seston loads and low nitrate concentrations appeared to limit photosynthetic activity. High rates of absolute DOC excretion were positively related to the particulate carbon production, although increased excretion percentages were found under high levels of both salinity and mean in the water column.
Formation of Surface-Bound Acyl Groups by Reaction of Acyl Halides on Ge(100)−2×1 (2006)

We have investigated the reaction of a series of acyl halides, including acetyl chloride, acetyl bromide, acetyl-d3 chloride, benzoyl chloride, and pivaloyl chloride, on Ge(100)-2x1 with multiple internal reflection infrared (MIR-IR) spectroscopy, X-ray photoelectron spectroscopy (XPS), and density functional theory (DFT). Infrared spectra following saturation exposures of acetyl chloride and acetyl bromide to Ge(100)-2x1 at 310 K are nearly identical, both exhibiting strong nu(C=O) stretching peaks near 1685 cm-1 and no vibrational modes in the nu(Ge-H) region. These data provide strong evidence for the presence of a surface-bound acetyl group on Ge(100)-2x1, which results from a C-X dissociation reaction (where X=Cl, Br). For acetyl chloride, DFT calculations predict that the barrier to C-Cl dissociation is only 1 kcal/mol above a chlorine-bound precursor state and is considerably smaller than barriers leading to the [2+2] C=O cycloaddition and alpha-CH dissociation products. In addition to the C-X dissociation product, both infrared and photoelectron results point to the presence of a second structure for acetyl halides where the oxygen of the surface-bound acetyl group donates charge to a nearby surface atom. This interaction is not observed for benzoyl chloride and pivaloyl chloride.
Activation of gp130 Transduces Hypertrophic Signals via STAT3 in Cardiac Myocytes (1998)

These results suggest that the STAT3-dependent signaling pathway downstream of gp 130 promotes cardiac myocyte hypertrophy under stimulation with LIF.
Assembly of Metal Nanoparticle Arrays Using Molecular Bridges (2001)

This article reviews recent work by our group aimed at organizing metal nanoparticles into symmetrically and spatially well defined architectures.
Interhemispheric Synchrony of Spontaneous Cortical States at the Cortical Column Level (2017)

In cat early visual cortex, neural activity patterns resembling evoked orientation maps emerge spontaneously under anesthesia. To test if such patterns are synchronized between hemispheres, we performed bilateral imaging in anesthetized cats using a new improved voltage-sensitive dye. We observed map-like activity patterns spanning early visual cortex in both hemispheres simultaneously. Patterns virtually identical to maps associated with the cardinal and oblique orientations emerged as leading principal components of the spontaneous fluctuations, and the strength of transient orientation states was correlated with their duration, providing evidence that these maps are transiently attracting states. A neural mass model we developed reproduced the dynamics of both smooth and abrupt orientation state transitions observed experimentally. The model suggests that map-like activity arises from slow modulations in spontaneous firing in conjunction with interplay between excitation and inhibition. Our results highlight the efficiency and functional precision of interhemispheric connectivity.
Development of Electrically Conductive Oligo(polyethylene glycol) Fumarate-Polypyrrole Hydrogels for Nerve Regeneration (2010)

Electrically conductive hydrogel composites consisting of oligo(polyethylene glycol) fumarate (OPF) and polypyrrole (PPy) were developed for applications in nerve regeneration. OPF-PPy scaffolds were synthesized using three different anions: naphthalene-2-sulfonic acid sodium salt (NSA), dodecylbenzenesulfonic acid sodium salt (DBSA), and dioctyl sulfosuccinate sodium salt (DOSS). Scaffolds were characterized by ATR-FTIR, XPS, AFM, dynamic mechanical analysis, electrical resistivity measurements, and swelling experiments. OPF-PPy scaffolds were shown to consist of up to 25 mol % polypyrrole with a compressive modulus ranging from 265 to 323 kPa and a sheet resistance ranging from 6 to 30 × 10(3) Ohms/square. In vitro studies using PC12 cells showed OPF-PPy materials had no cytotoxicity and PC12 cells showed distinctly better cell attachment and an increase in the percent of neurite bearing cells on OPF-PPy materials compared to OPF. The neurite lengths of PC12 cells were significantly higher on OPF-PPyNSA and OPF-PPyDBSA. These results show that electrically conductive OPF-PPy hydrogels are promising candidates for future applications in nerve regeneration.
Novel Insights into the Crosstalk between Mineralocorticoid Receptor and G Protein-Coupled Receptors in Heart Adverse Remodeling and Disease (2018)

The mineralocorticoid hormone aldosterone regulates sodium and potassium homeostasis but also adversely modulates the maladaptive process of cardiac adverse remodeling post-myocardial infarction. Through activation of its mineralocorticoid receptor (MR), a classic steroid hormone receptor/transcription factor, aldosterone promotes inflammation and fibrosis of the heart, the vasculature, and the kidneys. This is why MR antagonists reduce morbidity and mortality of heart disease patients and are part of the mainstay pharmacotherapy of advanced human heart failure. A plethora of animal studies using cell type&amp;ndash;specific targeting of the MR gene have established the importance of MR signaling and function in cardiac myocytes, vascular endothelial and smooth muscle cells, renal cells, and macrophages. In terms of its signaling properties, the MR is distinct from nuclear receptors in that it has, in reality, two physiological hormonal agonists: not only aldosterone but also cortisol. In fact, in several tissues, including in the myocardium, cortisol is the primary hormone activating the MR. There is a considerable amount of evidence indicating that the effects of the MR in each tissue expressing it depend on tissue- and ligand-specific engagement of molecular co-regulators that either activate or suppress its transcriptional activity. Identification of these co-regulators for every ligand that interacts with the MR in the heart (and in other tissues) is of utmost importance therapeutically, since it can not only help elucidate fully the pathophysiological ramifications of the cardiac MR`s actions but also help design and develop novel better MR antagonist drugs for heart disease therapy.&amp;nbsp; Among the various proteins the MR interacts with are molecules involved in cardiac G protein-coupled receptor (GPCR) signaling. This results in a significant amount of crosstalk between GPCRs and the MR, which can affect the latter`s activity dramatically in the heart and in other cardiovascular tissues. This review summarizes the current experimental evidence for this GPCR-MR crosstalk in the heart and discusses its pathophysiological implications for cardiac adverse remodeling as well as for heart disease therapy. Novel findings revealing non-conventional roles of GPCR signaling molecules, specifically of GPCR-kinase (GRK)-5, in cardiac MR regulation are also highlighted.
Parallel Overlay Grid Tet Mesh Generation With Combined Snapping & Cutting With Automatic CAD Defeaturing. (2021)

Abstract not provided.
Design of A D-band Transformer-Based Neutralized Class-AB Power Amplifier in Silicon Technologies (2019)

High-speed wireless communication in the post-5G era will likely make use of frequency bands above 100 GHz. This poses challenges to IC design in silicon technologies. This paper presents a general comparison of a D-band transformer-based Class-AB power amplifier with cross-coupled capacitive neutralization in three advanced silicon technologies: bulk CMOS, fully-depleted SOI, and SiGe BiCMOS. Each of these technologies has its own prospects and disadvantages. A comparison of performance parameters is made such as the maximum available power gain G <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">max</sub> , saturation power P <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">sat</sub> , drain efficiency DE and power added efficiency PAE after properly sizing the transistors to reach an optimum load resistance Ropt. Further, a 140 GHz 4-stage power amplifier is fabricated in a 28 nm bulk CMOS process as a reference. Its design considerations, layout parasitics analysis, and layout techniques are discussed as well.
Subwavelength grating crossings for silicon wire waveguides (2010)

We report on the design, simulation and experimental demonstration of a new type of waveguide crossing based on subwavelength gratings in silicon waveguides. We used 3D finite-difference time-domain simulations to minimize loss, crosstalk and polarization dependence. Measurement of fabricated devices show that our waveguide crossings have a loss as low as -0.023 dB/crossing, polarization dependent loss of < 0.02 dB and crosstalk <-40 dB.
Fundamental studies of strongly magnetic rare earth-transition metal alloys. Technical progress report, [June 19, 1991--June 18, 1992] (1992)

The goal of this project is to advance our understanding of new phases and microstructures of rare-earth and transition-metal alloys and compounds. In particular we investigate several classes of materials which are expected to have high magnetizations and coercivities, which are necessary conditions for high performance permanent magnet and related applications. Hard and semi-hard magnetic materials form the basis of much of the electric power and information storage industries and the discovery of new and less expensive materials with outstanding properties is of great interest.
Formation Efficiency of Porous Oxide Films in Aluminum Anodizing (2018)

Anodic oxidation of aluminum in acidic electrolytes is widely used for the formation of porous oxide films with a regular structure on the metal surface. Despite the century-old history of this process, the mechanism of channel ordering into a 2D hexagonal array is still not entirely clear. This work studies the modes of porous oxide film formation in 0.3 M oxalic acid at the anodizing voltages of 20 to 130 V and in 0.3 M sulfuric acid in the range of 19 to 60 V. The mass fraction of electrolyte impurities in the anodic aluminum oxide (AAO) structure, the formation efficiency, the volume expansion factor of the material in anodizing, and oxide film porosity are determined for the given conditions. The wide range of applied anodizing voltages allowed establishing a relationship between the degree of ordering of porous structures and the formation efficiency of anodic alumina and volume expansion of the material.
Fusion Image Quality Assessment Based on Modulation Transfer Function (2011)

This paper put forward a novel method fusion image quality assessment based on modulation transfer function (MTF) as a kind of objective guideline. Different temporal image from the same area was fused by Erdas and ENVI software using different methods. Fusion image quality assessment was implemented by comparing MTF curves from reference image and fusion image. The feasibility and reliability of MTF method were tested with remote sensing images. As showed in this paper, the MTF can describe objectively not only the quality of fusion images themselves, but the difference among fusion methods. Because of the coincidence of the assessment conclusion achieved by MTF method and human vision system (HVS), the MTF method has the character of combining with objectivity and subjectivity.
Brightness and color of the sky during the 2017 solar eclipse (2022)

Direct solar illumination disappears in the umbra when the Moon’s shadow creates a total solar eclipse. However, the sky above an observer in the umbra is not completely dark because of light that scatters into the umbra from the penumbra (partial eclipse region) and beyond. We show that a simple 2nd -order scattering model reproduces the brightness and color within a factor of 2 relative to measurements made with a radiometrically calibrated all-sky imaging system at the total solar eclipse of 21 August 2017 observed in Rexburg, Idaho USA. The model includes a first scattering point outside the umbra and a 2nd scattering point at the center of the umbra that redirects the light downward to the observer. The simulations show that the primary zenith skylight at the center of the umbra arises from light whose first scattering point is near an altitude of 10 km, the first scattering creates an orangish ring of light symmetrically around the horizon up to approximately 10° elevation, and the second scattering creates zenith skylight that is reduced by approximately four orders of magnitude from daylight and that has a slightly higher blue-red ratio than the daylight before and after the eclipse.
Copine-I: Modulator of NF-kappa B Transcription and Prostate Cancer Survival (2007)

Abstract : The purpose of our studies is to elucidate how Copine-I antagonizes NF-.B transcription. Nuclear factor-.B (NF-.B) is a dynamic transcription factor that regulates important biological processes involved in cancer initiation and progression. Identifying regulators that control the half-life of NF-.B is important to understanding molecular processes that control the duration of transcriptional responses. In this study we identify Copine-I, a calcium phospholipid-binding protein, as a novel repressor that physically interacts with p65 to inhibit NF-.B transcription. Knockdown of Copine-I by siRNA increases tumor necrosis factor a-stimulated NF-.B transcription, while Copine-I expression blocks endogenous transcription. Copine-I abolishes NF-.B transcription by inducing endoprotease processing of the N-terminus of p65, a process antagonized by I.Ba. Copine-I stimulates endoproteolysis of p65 within a conserved region that is required for base-specific contact with DNA. p65 proteins lacking the N-terminus fail to bind to DNA and act as dominant-negative molecules that inhibit NF-.B transcription. Our work provides evidence that Copine-I regulates the half-life of NF-.B transcriptional responses through a novel mechanism that involves endoproteolysis of the p65 protein. Copine has significance as a potential biomarker for therapeutic intervention in prostate cancer.
Role of tert‐Butyl Methyl Ether (TBME) as an External Donor in Propene Polymerization with Dibutyl Phthalate (DBP)‐Containing MgCl2‐Supported Ti Catalysts Activated with Al(i‐C4H9)3 (2004)

Abstract Summary: Stopped‐flow polymerization of propene was first conducted at 40 °C using the TiCl 4 /DBP/MgCl 2 catalyst (DBP = dibutyl phthalate) combined with Al(C 2 H 5 ) 3 . An induction period was observed at the beginning of polymerization, and the resulted polymer contained a considerable amount of the isolated ethylene unit. The formation of such unusual structures was concluded to be the result of copolymerization with ethylene originating from the ethylated Ti 4+ species. Catalyst washing with toluene and stopped‐flow polymerization at 70 °C brought about a drastic decrease in the contents of both Ti and DBP as well as a disappearance of both the induction period and isolated ethylene unit. The microstructures of polymers revealed that the highly stereoregular polymers are produced at the initial stage of polymerization. Changes in yield and molecular weight of polymers with polymerization time showed that the addition of tert ‐butyl methyl ether (TBME) brought about an increase in the concentration of active sites, but did not affect the propagation rate of propene polymerization. Such an increase in the active site concentration caused by an external donor has hardly been reported so far in kinetic studies using the stopped‐flow method; thus, the present result is believed to be a unique example. Kinetic curves of propene polymerization with the Cat. IV‐Al( i ‐C 4 H 9 ) 3 catalyst. (•): with TBME/Al = 0.1 and hydrogen, (♦): with TBME/Al = 0.1 and without hydrogen, (○): without TBME and with hydrogen, (⋄): without TBME and hydrogen. magnified image Kinetic curves of propene polymerization with the Cat. IV‐Al( i ‐C 4 H 9 ) 3 catalyst. (•): with TBME/Al = 0.1 and hydrogen, (♦): with TBME/Al = 0.1 and without hydrogen, (○): without TBME and with hydrogen, (⋄): without TBME and hydrogen.
Cerebral amyloid-β proteostasis is regulated by the membrane transport protein ABCC1 in mice (2011)

In Alzheimer disease (AD), the intracerebral accumulation of amyloid-β (Aβ) peptides is a critical yet poorly understood process. Aβ clearance via the blood-brain barrier is reduced by approximately 30% in AD patients, but the underlying mechanisms remain elusive. ABC transporters have been implicated in the regulation of Aβ levels in the brain. Using a mouse model of AD in which the animals were further genetically modified to lack specific ABC transporters, here we have shown that the transporter ABCC1 has an important role in cerebral Aβ clearance and accumulation. Deficiency of ABCC1 substantially increased cerebral Aβ levels without altering the expression of most enzymes that would favor the production of Aβ from the Aβ precursor protein. In contrast, activation of ABCC1 using thiethylperazine (a drug approved by the FDA to relieve nausea and vomiting) markedly reduced Aβ load in a mouse model of AD expressing ABCC1 but not in such mice lacking ABCC1. Thus, by altering the temporal aggregation profile of Aβ, pharmacological activation of ABC transporters could impede the neurodegenerative cascade that culminates in the dementia of AD.
581. The Epidemiology of Imipenem-Resistant Acinetobacter baumannii Bacteremia in a Pediatric Intensive Care Unit and Carbapenem Use (2019)

Abstract Background Acinetobacter baumannii (AB) infections cause high mortality and morbidity in intensive care unit patients. There are limited data on the epidemiology of imipenem-resistant A. baumannii (IRAB) amongst pediatric ICU patients. Methods A retrospective chart review was performed in patients with AB bacteremia in a pediatric intensive care unit at a tertiary teaching hospital from January 2000 to December 2016. Antimicrobial susceptibility tests, multilocus sequence typing (MLST) and PCR for antimicrobial resistance genes were performed for stored isolates. In addition, antibiotic prescription days of therapy (DOT per 1,000 patient-days) of the pediatric department from January 2001 to December 2016 was analyzed. Results Bacteremia episodes occurred in 27 patients. Male patients were 11 (41%) and the median age at the onset of bacteremia was 5.2 years (range, 0–18.6 years). There was a clear shift in antibiogram of AB during the study period. From 2000 to 2003, all isolates were imipenem-sensitive (ISAB, N = 6). From 2005 to 2008, both IRAB (N = 5) and ISAB (N = 4) were isolated. However, since 2009, all the AB isolates were IRAB (N = 12). In 33% (9/27) of patients, first AB was isolated from tracheal aspirate and patients developed bacteremia later (median duration from AB positive tracheal culture to AB positive blood culture, 8 days [range 5–124]). The overall mortality of patients with AB bacteremia was 59.3% (16/27) within 28 days. There was no statistical difference in mortality between ISAB and IRAB groups (50% vs. 71%; P = 0.42). From MLST analysis of 10 available isolates, sequence type 138 was predominant (N = 7). All 10 isolates were positive for OXA-23-like and OXA-51-like carbapenemase. In 2001, carbapenem DOT per 1,000 patient-days was 15.3 and later strikingly raised to 82.5 in 2009 when all the isolates were imipenem resistant. After this IRAB outbreak in PICU, proactive infection control and antimicrobial stewardship were reinforced among multidisciplinary teams in PICU. IRAB outbreak was terminated and carbapenem DOT per 1,000 patient-days was decreased to 51.7 in 2016. Conclusion IRAB bacteremia causes serious threat in high-risk pediatric patients in PICU. Proactive infection control measures and antimicrobial stewardship are crucial to manage serious IRAB infection in PICU. Disclosures All authors: No reported disclosures.
Clinical Investigation and Mechanism of Air-Bone Gaps in Large Vestibular Aqueduct Syndrome (2007)

We conclude that LVAS can present with an air-bone gap that can mimic middle ear disease. Diagnostic testing using acoustic reflexes, VEMPs, DPOAEs, and LDV can help to identify a non-middle ear source for such a gap, thereby avoiding negative middle ear exploration. A large vestibular aqueduct may act as a third mobile window in the inner ear, resulting in an air-bone gap at low frequencies.
ChemInform Abstract: Electrosprayed Nanoparticles and Electrospun Nanofibers Based on Natural Materials: Applications in Tissue Regeneration, Drug Delivery and Pharmaceuticals (2015)

Abstract Review: 236 refs.