gebhart/patrepeval huggingface dataset:
Lipid and Fatty Acid Contents in Red Tides from Tropical Fish Ponds of the Coastal Water of South China Sea (1996)

Microplanktonic red tide blooms (dominated by dinoflagellates) were observed in brackish water fish ponds of Terengganu between March 1992 to January 1993. The first short-lived bloom (2-3 days) occurred in October 1992 while the second long-lived bloom (6-7 days) occurred in January 1993. The dominant dinoflagellate species comprised of Peridinium quinquecorne (> 90% total cell count) with considerable proportion of Protoperidinium excentricum. Ciliophora consisting of Tintinopsis sp. and Favella sp. were also present during the bloom period. The total ash, chlorophyll, phaeopigment, lipid and fatty acid content of the microplankton were studied. Considerable amounts (6-11% of the total fatty acid) of the polyunsaturated fatty acid 18:3w3 (linolenic acid) were present in the microplankton. However, high amounts of 20:5w3 (eicosapentanoic acid) and 22:6w3 (docosahexaenoic acid) were present with variable but usually high amounts of 22:4w6 and 22:5w6 acids. The latter microplankton bloom contained higher amounts of 20:5w3 and 22:6w3 acids than the earlier bloom. Lipid content were three to five times higher than chlorophyll a. There was an increase with successive day after bloom outbreak in the relative proportion of total C18, C20, and C22 fatty acid components. The algae microplankton contained the w3-polyunsaturated fatty acids (PUFAs) probably needed for the growth and survival rate of grazing pond animals.
Postoperative deaths in children with portal hypertension. (1979)

69 children suffering from portal hypertension have been analysed. 5 of these patients died following shunt surgery, 2 after palliative surgery and 2 died in a state of haemorrhagic shock before any treatment could be commenced. In all those patients who died following shunt surgery, thrombosis in some part of the portal vein was found at post mortem. This led to partial liver necrosis.
A 281 Tflops calculation for X-ray protein structure analysis with special-purpose computers MDGRAPE-3 (2007)

We have achieved a sustained calculation speed of 281 Tflops for the optimization of the 3-D structures of proteins from the X-ray experimental data by the Genetic Algorithm - Direct Space (GA-DS) method. In this calculation we used MDGRAPE-3, special-purpose computer for molecular simulations, with the peak performance of 752 Tflops. In the GA-DS method, a set of selected parameters which define the crystal structures of proteins is optimized by the Genetic Algorithm. As a criterion to estimate the model parameters, we used the reliability factor R1 which indicates the statistical difference between the calculated and the measured diffraction data. To evaluate this factor it is necessary to reconstruct the diffraction patterns of the model structures every time the model is updated. Therefore, in this method the nonequispaced Discrete Fourier Transformation (DFT) used to calculate the diffraction patterns dominates most of the computation time. To accelerate DFT calculations, we used the special-purpose computer, MDGRAPE-3. A molecule, Carbamoyl-Phosphate Synthetase was investigated. The final reliability factors were much smaller than the typical values obtained in other methods such as the Molecular Replacement (MR) method. Our results successfully demonstrate that high-performance computing with GA-DS method on special-purpose computers is effective for the structure determination of biological molecules and the method has a potential to be widely used in near future.
MicroRNAs in Mesenteric Lymph and Plasma During Acute Pancreatitis (2014)

This study is the first to demonstrate both the presence of circulating miRNAs in lymph and the alteration of specific miRNAs in AP. Furthermore, these miRNAs alter in rat and human AP plasma and have potential to be explored as novel biomarkers of pancreatitis.
Multicolored Carbon Nanotubes: Decorating Patterned Carbon Nanotube Microstructures with Quantum Dots (2008)

In this work, techniques to create patterned array of multiwalled nanotube (MWNT) microstructures decorated with quantum dots (QDs) were presented. Using aligned array of intertwined MWNTs as the supporting template, a droplet of solution comprising QDs was deposited onto the MWNTs. When the solution evaporated away, QDs were left behind on the MWNT template. Coupled with the technique of laser pruning, a wide variety of QDs-decorated MWNT microstructures were created. In addition, the aligned array of MWNTs was found to be an effective nanosieve that could effectively sort out QDs with a size difference of approximately 0.5 nm. In this case, a droplet of solution comprising QDs of different sizes was placed on aligned array of MWNTs. As the solution spread across as well as trickled down the MWNTs, the smaller QDs were found to venture further and deeper into the MWNTs. Again coupled with laser pruning, fluorescence microscopy revealed multicolored MWNT microstructures due to preferential decoration of these QDs with difference sizes. As a result, multicolored/multicomponents hybrid functional materials were achieved.
Amplified flow-cytometric separation-free fluorescence immunoassays. (1985)

An equilibrium-type competitive-binding fluorescence immunoassay with high sensitivity and excellent precision is described that obviates separation of free from bound label. In the assay relatively large (10 microns diameter) antibody-coated non-fluorescent particles and very small (0.10 micron diameter) antigen-coated fluorescent latex particles are used. Soluble nonlabeled antigen competes with antigen on the microspheres for antibody binding sites on the larger spheres. After equilibrium is attained, the fluorescence distribution of 5000 of the large spheres is measured in a flow cytometer. The mean values for the fluorescence distribution obtained from samples containing known concentrations of soluble antigen are used to construct a standard displacement curve. In a prototype assay for the antigen horseradish peroxidase, a sensitivity of 10(-12) mol/L has been achieved. Undiluted serum can be assayed without loss of sensitivity. Preliminary experiments also indicate that double-antibody "sandwich"-type assays of very high sensitivity (10(-14) mol/L) are also possible when this dual-sphere concept is exploited.
Back gating of a two-dimensional hole gas in a SiGe quantum well (1997)

A device comprising a low-resistivity, n-type, Si substrate as a back gate to a p-type (boron), remote-doped, SiGe quantum well has been fabricated and characterized. Reverse and forward voltage biasing of the gate with respect to the two-dimensional hole gas in the quantum well allows the density of holes to be varied from 8×1011 cm−2 down to a measurement-limited value of 4×1011 cm−2. This device is used to demonstrate the evolution with decreasing carrier density of a re-entrant insulator state between the integer quantum Hall effect states with filling factors 1 and 3.
Nádorový supresor p53 zastavuje proliferaci a indukujediferenciaci monoblastů BM2 (2005)

Cilem nasi prace bylo urcit, zda transformacni funkci
onkoproteinu v-Myb v leukemických moneoblastech lze eliminovat
lidským proteinem p53. Za timto ucelem jsme v monoblastech BM2
exprimovali lidský gen p53 a vyhodnotili důsledky tohoto zasahu
pro jejich fenotyp. Zvýseni hladiny p53 způsobilo zastaveni
proliferace leukemických monoblastů BM2 ve fazi G2 buněcneho
cyklu. Soucasně buňky BM2 exprimujici p53 diferencovaly do
stadia vykazujiciho zvýsenou adherenci, fagocytarni aktivitu,
produkci kyslikových radikalů a aktivitu alfa-naftyl acetat
esterazy. Tyto vlastnosti charakterizuji dozravani monoblastů
do konecneho stadia makrofagů. Nase výsledky dokumentuji, že
nadorový supresor p53 je dominantni vzhledem k onkoproteinu
v-Myb, potlacuje jeho aktivitu v transformovaných buňkach a
umožňuje tak obnoveni jejich přirozene diferenciacni
schopnosti.
A novel planar, broadband, high gain lateral wave antenna array for body scanning applications (2020)

Abstract Three-dimensional body scanning systems are increasingly used in sensitive public areas such as airports. By providing a high resolution image of a person from all sides, it is possible to detect potential metallic, ceramic and explosive threats. For these systems, it is essential to design broadband antennas with a fan beam, highly directional radiation in one plane and wide in the other plane, and characterized by phase center stability as a function of frequency. In this paper, the planar lateral wave antenna (LWA) array is proposed to achieve these radiation requirements. The LWA has two critical shortcomings: the flaring part and the dielectric matching layers (MLs), to operate over very broad frequency bands. In this work, these shortcomings are overcomed by forming a connected array of planar LWAs to improve broadband performance and by applying necessary perforations on the dense dielectric lens antenna to create different effective relative permittivity regions. An eight element connected and perforated LWA array is designed to operate in the 8–24 GHz frequency band. The drilled holes are proved to play a similar critical role of MLs in internal reflection suppression. The results emphasize all crucial demands for body scanning systems.
ChemInform Abstract: GLYCOSIDIC COUPLING OF REGIOSPECIFICALLY SYNTHESIZED XANTHO(2,3‐G)TETRALIN AGLYCONES TO AFFORD ANTILEUKEMIC BUT REDOX INACTIVE STRUCTURES RELATED TO ANTHRACYCLINES (1985)

Abstract Zunächst werden aus (I) durch Hydroxylierung die Chromophore (II) synthetisiert und zu (IIIa) und (IIIb) deblockiert.
Finite Element Analysis in Combination with Perfectly Matched Layer to the Numerical Modeling of Acoustic Devices in Piezoelectric Materials (2013)

The characterization of finite length Surface Acoustic Wave (SAW) and Bulk acoustic Wave (BAW) resonators is addressed here. The Finite Element Analysis (FEA) induces artificial wave reflections at the edges of the mesh. In fact, these ones do not contribute in practice to the corresponding experimental response. The Perfectly Matched Layer (PML) method, allows to suppress the boundary reflections. In this work, we first demonstrate the basis of PML adapted to FEA formalism. Next, the results of such a method are depicted allowing a discussion on the behavior of finite acoustic resonators.
Charging effect simulation model used in simulations of plasma etching of silicon (2012)

Understanding the consequences of local surface charging on the evolving etching profile is a critical challenge in high density plasma etching. Deflection of the positively charged ions in locally varying electric fields can cause profile defects such as notching, bowing, and microtrenching. We have developed a numerical simulation model capturing the influence of the charging effect over the entire course of the etching process. The model is fully integrated into ViPER (Virtual Plasma Etch Reactor)—a full featured plasma processing simulation software developed at Ilmenau University of Technology. As a consequence, we show that local surface charge concurrently evolves with the feature profile to affect the final shape of the etched feature. Using gas chopping (sometimes called time-multiplexed) etch process for experimental validation of the simulation, we show that the model provides excellent fits to the experimental data and both, bowing and notching effects are captured—as long as the evolving profile and surface charge are simultaneously simulated. In addition, this new model explains that surface scallops, characteristic of gas chopping technique, are eroded and often absent in the final feature profile due to surface charging. The model is general and can be applied across many etching chemistries.
Advantages of histamine H4 receptor antagonist usage with H1 receptor antagonist for the treatment of murine allergic contact dermatitis (2012)

Histamine facilitates development of eczematous lesions in chronic allergic contact dermatitis. In addition to the well-known corticosteroid treatments, H1 receptor (H1R) antagonists also have been used. This study observed effects of histamine H4 receptor (H4R) antagonist usage with H1R antagonist in a murine chronic allergic contact dermatitis model, developed by repeated percutaneous challenge to the dorsal skin with 2,4,6-trinitro-1-chlorobenzene (TNCB). The H1R antagonist olopatadine hydrochloride and/or the H4R antagonist JNJ7777120 was then administered. Combination therapy was more effective than H1R antagonist monotherapy. Serum IgE and levels of interleukin (IL)-4, IL-5 and IL-6 (Th2 cytokines) in eczematous lesions decreased with combined therapy. Combined therapy with H1R and H4R antagonists counteracts the disadvantages of each as monotherapeutic agents and potentially represents a new strategy for the treatment of chronic allergic contact dermatitis.
Protective Effects of Berry Volatiles on Lipopolysaccharide-Induced Acute Lung Injury in Human A549 Cells (2021)

Berry volatiles are primary or secondary compounds produced when tissue disrupts, and responsible for the flavor and aroma of berries. Berry volatiles has been recently reported to have anti-inflammatory effect. Acute lung injury is one of the severe consequences of lung inflammation increasing respiratory stress and pulmonary edema with high mortality. Thus, the objective of this study was to investigate the anti-inflammatory effect of three berry volatiles (blackberry, black raspberry, and blueberry) on lipopolysaccharide (LPS)-induced acute lung injury in lung epithelial A549 cells and its mechanism. A549 cells were pretreated with three different dilutions (2, 4, and 8-fold) of blackberry, black raspberry, and blueberry volatile extract for 1 h. Cells were then stimulated with or without LPS (10 μg/mL) for 24 h. The cell viability was measured with one-step diphenyl tetrazolium bromide (MTS) assay. The level of pro-inflammatory cytokines in the culture media was examined by using enzyme-linked immunosorbent assay (ELISA) kit. Apoptosis of A549 cells were evaluated by using death detection ELISA kit. All statistical tests were analyzed by using one-way ANOVA, followed by Tukey's multiple comparisons. Significant difference was defined at P < 0.05. Two-fold diluted berry volatiles (blackberry, black raspberry, and blueberry) significantly decreased A549 cell viability by 24%, 52% and 61%, respectively compared to the control (P < 0.05). Concentration of interleukin-8 (IL-8) was remarkably higher when LPS stimulated A549 cells compared to the control (P < 0.05). However, 2-fold diluted berry volatiles significantly suppressed LPS-induced IL-8 level compared to LPS treated group (P < 0.01). 2-fold diluted blackberry, black raspberry, and blueberry volatiles also showed significant apoptotic effect on A549 cells compared to the control (P < 0.05). These results showed that blackberry, black raspberry, and blueberry volatiles suppress inflammatory responses by modulating pro-inflammatory cytokines and apoptosis. This study suggests that volatiles from berries (blackberry, black raspberry, and blueberry) may have a potential impact on lung inflammation. Arkansas Biosciences Institute.
Second-harmonic generation in periodically poled nonlinear polymer waveguides (2004)

We demonstrate quasi-phase-matched (QPM) second-harmonic generation (SHG) at the optical communication wavelengths with side-chain polymer waveguides. A ridge waveguide structure is designed to support fundamental mode guiding at both the pump and the second harmonics, leading to a high field overlap integral of the guided modes. The nonlinearity contrast in the +/0 type QPM waveguide is maximized under a QPM poling electrode width of nearly half the coherence length. Using these configurations, we record a normalized SHG efficiency of 2.2% W(-1) cm(-2) in the polymer waveguide.
Palladium-Catalyzed C–H Acylation of Arenes Directed by 1,2,3-Triazole (2016)

This Letter has been retracted by the authors upon request of the Editorial Board for reasons of significant content overlap with a parallel submission to another journal.1 The EJOC article was published first on October 4th and the Synlett article was submitted on September 30th and accepted November 25th 2016. The Editorial Board recognizes that, had the submission to Eur. J. Org. Chem. (submitted one month prior to this Synlett manuscript), been referenced and its contents disclosed, the striking similarities between the two articles would have been noted and the Synlett Letter would not have been accepted for publication. (1) Palladium-Catalyzed Acylation of Arenes by 1,2,3-Triazole-Directed C-H Activation, Zhao, F.; Chen, Z.; Liu, Y.; Xie, K.; Jiang, Y. Eur. J. Org. Chem. 2016, 5971.
Improved design and characterisation method for ECL very high speed circuits (2004)

A procedure to design and characterise high speed bipolar circuits is presented. The design method is improved by using iso base-collector capacitance curves and duty cycles plots in the (IC, Vce) plane. This new optimisation way gives the optimum electrical parameters for each transistor of a bipolar circuit to reach the best trade-off between the switching speed and the power consumption. Furthermore, input signals time jitter is taken into account during simulations. The measurement method is improved by characterising in time domain each part of the measurement set-up. These improvements have enabled the design and characterisation of InP-DHBT D-type flip-flop and demultiplexer circuits. 40 Gbit/s on wafer measurement are presented.
Comparison of pharmacotherapy before and after electroshock therapy for maintenance treatment in senile depressive patients (1998)

S: The 7th Annual Meeting of the Japanese Society of Clinical Neuropsychopharmacology, Tokyo, Japan, 20–21 November 1997: PDF Only
A REVIEW ON DETECTION METHODS FOR IRRADIATED FOOD (2004)

Current problems on food irradiation techniques and many detection methods such as photostimulated luminescence (PSL), thermoluminescence(TL), electron spin resonnance (ESR) and direct epifluorescent filter technique /aerobic plate count (DEFT/APC) have been concluded in this paper.
A fault tolerance framework for CORBA (2003)

We describe a fault tolerance framework for CORBA that provides fault tolerance management and core services, implemented above the ORB for ease of use and customization, and fault tolerance mechanisms, implemented beneath the ORB for transparency and efficiency. Strong replica consistency is facilitated by a multicast engine that provides reliable totally ordered delivery of multicast messages to the replicas of an object. Transparency to the application allows application programmers to focus on their applications rather than on fault tolerance, and transparency to the ORE allows existing commercial CORBA ORBs to be used without modification. The fault tolerance framework adheres to CORBA's objective of interoperability by ensuring that different implementations of the specifications of the framework can interoperate and that non-fault-tolerant objects can interwork with fault-tolerant objects.
Study on the characteristics of electrical discharge machining (EDM) in real operation. (1987)

In order to realize EDM with high accuracy, several factors which affect to the error in EDM were taken into consideration.The in-process measurements of the force and the displacement of the main axis, the displacement of the head, the average current and the average voltage have been done at the same time.The time series of measured date mentioned above are investigated mutually, and the following results are obtained.(1) The main axis receives the force caused by the viscosity of dielectric fluid. This force becomes large in case of using the electrode with large area or in case of very small gap distance between the electrode and the work. The column is deformed by this force, and consequently machining accuracy becomes lower.(2) Machined error by the force above-mentioned are expected to decrease by the improvement of the control performance of main axis.
A novel mechatronic tool for computer-assisted arthroscopy (2000)

This paper describes a novel mechatronic tool for arthroscopy, which is at the same time a smart tool for traditional arthroscopy and the main component of a system for computer-assisted arthroscopy. The mechatronic arthroscope has a cable-actuated servomotor-driven multi-joint mechanical structure, is equipped with a position sensor measuring the orientation of the tip and with a force sensor detecting possible contact with delicate tissues in the knee, and incorporates an embedded microcontroller for sensor signal processing, motor driving and interfacing with the surgeon and/or the system control unit. When used manually, the mechatronic arthroscope enhances the surgeon's capabilities by enabling him/her to easily control tip motion and to prevent undesired contacts. When the tool is integrated in a complete system for computer-assisted arthroscopy, the trajectory of the arthroscope is reconstructed in real time by an optical tracking system using infrared emitters located in the handle, providing advantages in terms of improved intervention accuracy. The computer-assisted arthroscopy system comprises an image processing module for segmentation and three-dimensional reconstruction of preoperative computer tomography or magnetic resonance images, a registration module for measuring the position of the knee joint, tracking the trajectory of the operating tools, and matching preoperative and intra-operative images, and a human-machine interface that displays the enhanced reality scenario and data from the mechatronic arthroscope in a friendly and intuitive manner. By integrating preoperative and intra-operative images and information provided by the mechatronic arthroscope, the system allows virtual navigation in the knee joint during the planning phase and computer guidance by augmented reality during the intervention. This paper describes in detail the characteristics of the mechatronic arthroscope and of the system for computer-assisted arthroscopy and discusses experimental results obtained with a preliminary version of the tool and of the system.
Keeping in touch with contact inhibition of locomotion (2010)

Contact inhibition of locomotion (CIL) is the process by which cells in vitro change their direction of migration upon contact with another cell. Here, we revisit the concept that CIL plays a central role in the migration of single cells and in collective migration, during both health and disease. Importantly, malignant cells exhibit a diminished CIL behaviour which allows them to invade healthy tissues. Accumulating evidence indicates that CIL occurs in vivo and that regulation of small Rho GTPases is important in the collapse of cell protrusions upon cell contact, the first step of CIL. Finally, we propose possible cell surface proteins that could be involved in the initial contact that regulates Rho GTPases during CIL.