gebhart/patrepeval huggingface dataset:
Defective cell proliferation in the floral meristem of alloplasmic plants of Nicotiana tabacum leads to abnormal floral organ development and male sterility (2001)

Flowers of an alloplasmic male-sterile tobacco line, comprised of the nuclear genome of Nicotiana tabacum and the cytoplasm of Nicotiana repanda, develop short, poorly-pigmented petals and abnormal sterile stamens that often are fused with the carpel wall. The development of flower organ primordia and establishment of boundaries between the different zones in the floral meristem were investigated by performing expression analysis of the tobacco orthologs of the organ identity genes GLO, AG and DEF. These studies support the conclusion that boundary formation was impaired between the organs produced in whorls 3 and 4 resulting in partial fusions between anthers and carpels. According to the investigations cell divisions and floral meristem size in the alloplasmic line were drastically reduced in comparison with the male-fertile tobacco line. The reduction in cell divisions leads to a discrepancy between cell number and cell determination at the stage when petal and stamen primordia should be initiated. At the same stage expression of the homeotic genes was delayed in comparison with the male-fertile line. However, the abnormal organ development was not due to a failure in the spatial expression of the organ identity genes. Instead the aberrant development in the floral organs of whorls 2, 3 and 4 appears to be caused by deficient floral meristem development at an earlier stage. Furthermore, defects in cell proliferation in the floral meristem of the alloplasmic male-sterile line correlates with presence of morphologically modified mitochondria. The putative causes of reduced cell number in the floral meristem and the consequences for floral development are discussed.
Penumbral cones and Purkinje trees (2014)

The retinal vasculature lies between the cornea and the retina and consists of a fine network of blood vessels which filter the light impinging on the retina, and cast shadows on the retinal mosaic. The light seen by cones in the partial shadow of the blood vessels is filtered according to the transmittance properties of hemoglobin. The entoptic visualization of the retinal blood vessels has been known since at least J. E. Purkinje (1823) and is typically evoked using a moving light source which shifts the shadow of the blood vessels to cones adjacent to the penumbral and umbral cones, thus rendering the so-called Purkinje tree visible. Here, we used the method of silent substitution using a multi-primary (56 primaries) spectral illumination system (OneLight Spectra Digital Light Engine) to produce a spectral modulation which silenced L, M, S cones and melanopsin under photopic conditions and selectively stimulated penumbral L and M cones. This modulation elicits a strong and vivid percept of one's own Purkinje tree. We find that this modulation produces BOLD fMRI responses in primary visual cortex, and that it elicits a considerably stronger amplitude than full-field L and M cone modulation matched in contrast. The V1 response peaks at a modulation frequency of 16 Hz and is presumably attributable to the pronounced spatial structure in the observed percept. We note that inadvertent penumbral cone stimulation could confound silent substitution paradigms directed towards other photoreceptor classes. Support: NIH R01 EY020516, R01 EY10016, P30 EY001583; Deutscher Akademischer Austauschdienst. Disclosure: A patent on the alternative photoreceptor isolation technique and its applications has been filed by the University of Pennsylvania with G.K.A., D.H.B., and M.S. as inventors.
A Phase-Shifted-PWM D-STATCOM Using a Modular Multilevel Cascade Converter (SSBC)—Part I: Modeling, Analysis, and Design of Current Control (2014)

This paper presents and discusses a phase-shifted-PWM distribution static synchronous compensator (D-STATCOM) using the modular multilevel cascade converter based on single-star bridge cells (MMCC-SSBC). A three-phase 140-V 10-kVA SSBC-based STATCOM with a cascade count N=6 is designed, constructed, and tested for verifying the performance and functionality of the medium-voltage D-STATCOM in both steady and transient states. The 13-level line-to-neutral (25-level line-to-line) voltage at the ac side yields an almost sinusoidal line current with a total harmonic distortion value of 1.7%. An analytical model for the phase-shifted PWM is proposed to design the current control gains. Two phase-shifted PWM methods, which are named as one-cell and all-cells update methods, are theoretically and experimentally compared. The all-cells update method can reduce the inherent time delay, thus resulting in a faster and more stable system response than the one-cell update method.
Volumetric properties of gaseous acetone (1968)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTVolumetric properties of gaseous acetoneL. N. Anderson, A. P. Kudchadker, and P. T. EubankCite this: J. Chem. Eng. Data 1968, 13, 3, 321–327Publication Date (Print):July 1, 1968Publication History Published online1 May 2002Published inissue 1 July 1968https://pubs.acs.org/doi/10.1021/je60038a007https://doi.org/10.1021/je60038a007research-articleACS PublicationsRequest reuse permissionsArticle Views295Altmetric-Citations25LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Twinning in TiSi2-island catalyzed Si nanowires grown by gas-source molecular-beam epitaxy (2002)

Using TiSi2 islands as a catalyst, we have grown Si nanowires by gas-source molecular-beam epitaxy using Si2H6 as the gas source. The dominant TiSi2 islands are C49 phase with the orientation: Si[110]//C49-TiSi2[100] and Si(001)//C49-TiSi2(010). Twinning in the grown Si nanowires is observed by reflection high-energy electron diffraction and transmission electron microscopy. The twining also causes kinking, i.e., an abrupt change of growth direction of the Si nanowires. Lattice mismatch stress between the TiSi2 islands and the Si nanowires possibly leads to twinning and kinking of the Si nanowires.
Sensory and Marketing Characteristics of a Hibiscus Beverage (2010)

Food Consumption/Nutrition/Food Safety, Industrial Organization, International Relations/Trade, Marketing
A General Fortran Emulator For Ibm 360/370 Random Number Generator “Randu” (1975)

The purpose of this paper is to present a general FORTRAN emulator routine for IBM'S RANDU random number generator. The emulator should be useful to those having to convert simulation programs from IBM to other systems. It has been thoroughly tested on a CDC 6400 and should run without modification on other machines.
Modified Oxygen Vacancy Induced Fermi Level Pinning Model Extendable to P-Metal Pinning (2006)

Typical p-metals show similar effective work functions close to p+ polycrystalline silicon (poly-Si) pinning position irrespective of materials after high-temperature process. We found that this phenomenon can be explained by the modified Vo model taking into account the effect of Si substrate. Oxygen absorption by Si substrate and subsequent electron transfer to metal electrode clearly explain the p-metal Fermi level pinning as well as p+ poly-Si pinning. In addition, unsuppressed Fermi level pinning by insertion of barrier layer at p+ poly-Si/barrier layer/high-k gate stack, which is one of the open issues concerning p+ poly-Si pinning, has the same overall reaction scheme. The modified model also consistently explains this phenomenon.
Impedance-based stability analysis of DFIG (2016)

Impedance-based method is applied in this paper to analyze the relationship between the converter control system and the stability of DFIG grid connected system. The model of DFIG equivalent input admittance considering the phase error of controller system caused by PLL is proposed. The impact of controller proportional and integral gains is analyzed according to the proposed model. Stability of the DFIG system connected to weak grid can be predicted with the proposed input admittance model using GNC. Simulation results verify the validity of the proposed equivalent DFIG input admittance and the stability analysis.
Pseudomonas aeruginosa alters inflammatory response of primary bronchial epithelial cells to Rhinovirus infection in vitro (2020)

The effects of chronic bacterial infections on susceptibility to and course of viral infections in the lung is still insufficiently understood. Here we investigated whether a co-infection with Pseudomonas aeruginosa (PA) changes the inflammatory response of primary bronchial epithelial cells (pBECS) to rhinovirus infection.
Nickel-induced conversion of carbon–nitrogen into carbon–carbon bonds. One-step transformations of aryl, quaternary ammonium salts into alkylarenes and biaryls (1988)

Aryltrimethylammonium iodides are shown to undergo reaction with Grignard reagents under phosphine-ligated, low-valent nickel catalysis with the formation of alkylarenes and biaryls.
Data from Regulation of eIF4F Translation Initiation Complex by the Peptidyl Prolyl Isomerase FKBP7 in Taxane-resistant Prostate Cancer (2023)

&lt;div&gt;AbstractPurpose:&lt;p&gt;Targeted therapies that use the signaling pathways involved in prostate cancer are required to overcome chemoresistance and improve treatment outcomes for men. Molecular chaperones play a key role in the regulation of protein homeostasis and are potential targets for overcoming chemoresistance.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; We established 4 chemoresistant prostate cancer cell lines and used image-based high-content siRNA functional screening, based on gene-expression signature, to explore mechanisms of chemoresistance and identify new potential targets with potential roles in taxane resistance. The functional role of a new target was assessed by &lt;i&gt;in vitro&lt;/i&gt; and &lt;i&gt;in vivo&lt;/i&gt; silencing, and mass spectrometry analysis was used to identify its downstream effectors.&lt;/p&gt;Results:&lt;p&gt;We identified FKBP7, a prolyl-peptidyl isomerase overexpressed in docetaxel-resistant and in cabazitaxel-resistant prostate cancer cells. This is the first study to characterize the function of human FKBP7 and explore its role in cancer. We discovered that FKBP7 was upregulated in human prostate cancers and its expression correlated with the recurrence observed in patients receiving docetaxel. &lt;i&gt;FKBP7&lt;/i&gt; silencing showed that FKBP7 is required to maintain the growth of chemoresistant cell lines and chemoresistant tumors in mice. Mass spectrometry analysis revealed that FKBP7 interacts with eIF4G, a component of the eIF4F translation initiation complex, to mediate the survival of chemoresistant cells. Using small-molecule inhibitors of eIF4A, the RNA helicase component of eIF4F, we were able to kill docetaxel- and cabazitaxel-resistant cells.&lt;/p&gt;Conclusions:&lt;p&gt;Targeting FKBP7 or the eIF4G-containing eIF4F translation initiation complex could be novel therapeutic strategies to eradicate taxane-resistant prostate cancer cells.&lt;/p&gt;&lt;/div&gt;
Development of LD-pumped 10 J x 10 Hz Nd:glass slab laser (1999)

We have proposed and designed a diode-pumped solid-state laser (DPSSL) driver for inertial fusion energy (IFE) which consists of water-cooled zig-zag path Nd:glass slab amplifiers. A driver module has 10 kJ total output energy at 351 nm and operates at 12 Hz with 10.4 percent overall efficiency. The laser driver producing 4 MJ blue output for IFE will consists of 400 modules. To confirm the design, we are developing a small scale DPSSL module of 10J X 10Hz laser output at 1053 nm.
Data from Repurposing Tin Mesoporphyrin as an Immune Checkpoint Inhibitor Shows Therapeutic Efficacy in Preclinical Models of Cancer (2023)

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; Unprecedented clinical outcomes have been achieved in a variety of cancers by targeting immune checkpoint molecules. This preclinical study investigates heme oxygenase-1 (HO-1), an immunosuppressive enzyme that is expressed in a wide variety of cancers, as a potential immune checkpoint target in the context of a chemotherapy-elicited antitumor immune response. We evaluate repurposing tin mesoporphyrin (SnMP), which has demonstrated safety and efficacy targeting hepatic HO in the clinic for the treatment of hyperbilirubinemia, as an immune checkpoint blockade therapy for the treatment of cancer.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; SnMP and genetic inactivation of myeloid HO-1 were evaluated alongside 5-fluorouracil in an aggressive spontaneous murine model of breast cancer (&lt;i&gt;MMTV-PyMT&lt;/i&gt;). Single-cell RNA sequencing analysis, tumor microarray, and clinical survival data from breast cancer patients were used to support the clinical relevance of our observations.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt; We demonstrate that SnMP inhibits immune suppression of chemotherapy-elicited CD8&lt;sup&gt;+&lt;/sup&gt; T cells by targeting myeloid HO-1 activity in the tumor microenvironment. Microarray and survival data from breast cancer patients reveal that HO-1 is a poor prognostic factor in patients receiving chemotherapy. Single-cell RNA-sequencing analysis suggests that the myeloid lineage is a significant source of HO-1 expression, and is co-expressed with the immune checkpoints PD-L1/2 in human breast tumors. &lt;i&gt;In vivo,&lt;/i&gt; we therapeutically compare the efficacy of targeting these two pathways alongside immune-stimulating chemotherapy, and demonstrate that the efficacy of SnMP compares favorably with PD-1 blockade in preclinical models.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusions:&lt;/b&gt; SnMP could represent a novel immune checkpoint therapy, which may improve the immunological response to chemotherapy. &lt;i&gt;Clin Cancer Res; 24(7); 1617–28. ©2018 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;
Index profile measurement of asymmetrical elliptical preforms or fibers (1987)

An extension of the beam-deflection method to the case of elliptical preforms with eccentric core (asymmetrical elliptical preforms) is presented, which can be easily implemented on automatic measurement equipment
COMPACT THICK METAL DIPLEXER WITH MULTI-COUPLED FOLDED HALF WAVELENGTH RESONATORS (2011)

A thick metal microstrip diplexer is presented. The circuit is based on compact folded half wavelength resonators and uses a source/load-multi-resonator coupling method providing improved performance and greater design ∞exibility. Source/load coupling with multiple resonators introduces additional transmission zeros, and this coupling is enhanced by using high-aspect-ratio metal structures. Tall, narrow metal arms connected to the ports and extended to the non-adjacent resonators provide efiective multi-resonator bypass coupling. The high-aspect-ratio diplexer fabricated using polymer- based deep X-ray lithography and 0.22mm thick metal electroplating demonstrates the advantages of thick metal structures for coupled resonator applications.
A multicentre, double-blind randomized crossover comparative study on the efficacy and safety of dofetilide vs sotalol in patients with inducible sustained ventricular tachycardia and ischaemic heart disease (2001)

Dofetilide was as efficacious as sotalol in preventing the induction of sustained ventricular tachycardia. There was no concordance in the response rate in two-thirds of the patients. Dofetilide was significantly better tolerated during the acute phase than sotalol. Both dofetilide and sotalol were well tolerated during the long term with no statistically significant difference in the adverse events.
<title>In-line phase-shifter calibration and drift measurement and compensation for digital speckle pattern interferometry (DSPI)</title> (1996)

Few conditions are absolutely necessary to improve the accuracy of quantitative measurements of displacements in an interferometer: the accurate calibration of the phase- shifter, the control and the suppression of the interferometers drift. Calibration consists in measuring phase shifts generated by piezoelectric transducers (PZT). We have developed an original in-line PZT calibration based on speckles intensity modulation. A new method to measure the phase drift versus time in the whole interferometer (reference and object arm) is presented. Two innovative methods to compensate phase drift in real time allow accurate displacements measurements. Both compensation methods do not use a feedback loop active control during DSPI measurements. So it allows us to avoid overshoot or oscillation problems linked to the feedback loop. All presented methods allow inexpensive data processing and were successfully applied to an out-of-plane sensitive interferometer. PZT calibration, drift measurements and real time compensation are automated.
Accuracy of topographic measurements in a model eye with the laser tomographic scanner. (1991)

The authors evaluated the accuracy of topographic measurements with the laser tomographic scanner using a model eye. Diameter, depth, and shape at different axial lengths of four sample holes that simulated optic nerve heads in phakic and aphakic conditions were determined by confocal imaging. The computer-generated cross-section profiles of the simulated optic nerve heads corresponded well with the actual contours as photographed by scanning electron microscopy. The average relative error in diameter was 2.0% (range: 0.3-2.9%) for the phakic model eye and 3.6% (range: 0.6-8.2%) for the aphakic model eye. The average relative error in depth was 11.7% (range: 1.2-20.1%) for the phakic model eye and 10.1% (range: 1.7-22.6%) for the aphakic model.
Stable direct adaptive periodic control using only plant order knowledge (1996)

The main contribution of this paper is to put stability requirements for convergence of direct adaptive periodic controllers on an equal footing with requirements for indirect adaptive periodic control as set forth by Lozano. The resulting stability condition is simply that the plant order is known a priori. No other prior plant knowledge is used (e.g. relative degree, high-frequency gain, etc.) and persistent excitation is not required. More importantly, no assumption or knowledge is required as to whether the plant is minimum or non-minimum phase. A numerical example is given to demonstrate the method and some guidelines are given for improving the adaptive transient response.
ChemInform Abstract: Superconducting Double Perovskite Bismuth Oxide Prepared by a Low‐Temperature Hydrothermal Reaction. (2014)

Abstract The double perovskite (Na 0.25 K 0.45 )(Ba 1.00 ) 3 (Bi 1.00 ) 4 O 12 is hydrothermally synthesized from an aqueous mixture of NaBiO 3 , Ba(OH) 2 , and KOH (autoclave, 220 °C) and characterized by powder XRD, TEM, magnetic susceptibility, and electrical resistivity measurements.
A two-component image coding scheme based on two-dimensional interpolation and the discrete cosine transform (2005)

An image coding algorithm is developed which exploits some of the desirable features of the spatial and the transform domains for image data compression. This scheme is based on a two-component source model similar to some previous results [1 ,2] , but has been generalized to include two-dimensional interpolation and transform coding. Rather than processing successive scan lines of image intensity, this algorithm approximates the image intensity over adjacent subpictures using a two-dimensional polynomial and codes the residual intensities using a discrete cosine transform (DCT). Compression results with rates in the 0.5 to 1.0 bits per pixel range are demonstrated by reconstructed images and rate-distortion characteristics.
Laparoscopic adrenalectomy for co-secreting aldosterone and cortisol adenomas (2012)

There are few published data on aldosterone and cortisol co-secreting adrenal tumours. Failure to perform comprehensive preoperative endocrine investigations in patients with adrenal "incidentalomas" or in those thought to be secreting only one hormone may account for this. Clinically patients with such lesions may have evidence of hypertension and hypokalaemia with no features of cortisol excess. Preoperative diagnosis of such lesions with accurate endocrinological work up is essential to prevent adrenal insufficiency and haemodynamic crises following removal of such glands. We present a series of 4 patients with co-secreting tumours treated by laparoscopic adrenalectomy between September 2010 and March 2011. Our experience suggests that dual secretors are more common than originally thought. A high index of suspicion and adequate endocrine work up is paramount in diagnosing such tumours and in experienced hands, laparoscopic adrenalectomy with appropriate substitutive steroid cover is safe, feasible and curative for these functioning adrenal tumours.
[Ambulatory aerosol therapy in the treatment of chronic pathology of the O.R.L. region]. (1991)

This study considers the efficacity of the ambulatory aerosol therapy in chronic cases of the ENT area. A nebulizer, air-jet type, of 4 microns MMAD, was the device employed, and an ample spectre antibiotic (cefotaxime) a mucolytic (N-acetyl-cysteine) plus a corticoid (methyl-prednisolone) the associated drugs. The antibiotic was discarded when otitis were the problem. The results have been favourable in 75 percent of the cases whilst negative in the resting 24 percent of the treated subjects.
Prevalence of Toxoplasma gondii in Belgian wildlife (2011)

International audience
Integration of Distributed Temperature and Distributed Acoustic Survey Results with Hydraulic Fracture Modeling: A Case Study in the Woodford Shale (2015)

Summary A unique data set was acquired in 2012-2013 during hydraulic fracturing operations in the Cana Field, Canadian County, Oklahoma. The Cana field produces from the Woodford shale using horizontal wells completed nine wells to a section. The data set was acquired during completion operations on the McCray 2-26H well and included the acquisition of distributed temperature sensing (DTS), distributed acoustic sensing (DAS), bottomhole pressure data, surface and downhole microseismic, tracer logs, and post-treatment production logs. Diagnostic fracture injection test DFIT data and other reservoir characterization information were also available from the subject and offset wells. The McCray 2-26H was completed with twelve hydraulic fracturing stages that had a variety of jet nozzle cluster spacings.