gebhart/patrepeval huggingface dataset:
Effect of cyclophosphamide on Friend virus leukemogenesis in virus-sensitive and virus-resistant mice. (1985)

The influence of cyclophosphamide (CY) on Friend virus leukemogenesis was studied in SJL/J, C57BL/10J, and C57BL/10J X SJL/J F1 (hereafter called B10SJF1) mice. All three differ in their susceptibility to the viral oncogenic effect. Immunosuppressive doses of CY, which by themselves produced no cancer, were followed 2 days later by injection of Friend leukemia virus. The virus doses were the same as used previously. Although in other experiments preinjection of various chemical carcinogens augmented leukemogenesis by Friend leukemia virus in SJL/J mice, in the present study, pretreatment by CY had no such effect. In contrast, CY increased Friend erythroleukemia incidence from 15 to 100% in B10SJF1 mice and from 0 to 85% in C57BL/10J mice. The disease in C57BL/10J mice had a 190-day incubation period, which is approximately 5 times that in the SJL/J and B10SJF1 mice. During this latent period, the C57BL/10J mice harbored infectious Friend leukemia virus in their plasma.
Cyogenic Thermal Conductivity Measurements of Yb:YAG Ceramics (2022)

Thermal conductivity of 9.8 at% Ytterbium-doped Yttrium Aluminum Garnet (Yb:YAG) ceramics has been measured by three systems at Commissariat à l'Énergie Atomique et aux énergies alternatives (CEA Paris-Saclay) and at the National Institute for Fusion Science (NIFS). For accurate measurements, thermal impedances in thermal systems should be negligibly small. However, each system includes some thermal impedance in a heat flow path. This paper describes that thermal conductivity of the 9.8% doped Yb:YAG ceramics and discusses the compensation method for thermal impedance in each system.
Hybrid Pre-Log and Post-Log Image Reconstruction for Computed Tomography (2017)

Tomographic image reconstruction for low-dose computed tomography (CT) is increasingly challenging as dose continues to reduce in clinical applications. Pre-log domain methods and post-log domain methods have been proposed individually and each method has its own disadvantage. While having the potential to improve image quality for low-dose data by using an accurate imaging model, pre-log domain methods suffer slow convergence in practice due to the nonlinear transformation from the image to measurements. In contrast, post-log domain methods have fast convergence speed but the resulting image quality is suboptimal for low dose CT data because the log transformation is extremely unreliable for low-count measurements and undefined for negative values. This paper proposes a hybrid method that integrates the pre-log model and post-log model together to overcome the disadvantages of individual pre-log and post-log methods. We divide a set of CT data into high-count and low-count regions. The post-log weighted least squares model is used for measurements in the high-count region and the pre-log shifted Poisson model for measurements in the low-count region. The hybrid likelihood function can be optimized using an existing iterative algorithm. Computer simulations and phantom experiments show that the proposed hybrid method can achieve faster early convergence than the pre-log shifted Poisson likelihood method and better signal-to-noise performance than the post-log weighted least squares method.
Activity of Lactobacillus brevis Alcohol Dehydrogenase on Primary and Secondary Alcohol Biofuel Precursors (2015)

The R-specific alcohol dehydrogenase (ADH) from Lactobacillus brevis LB19 (LbADH) was studied with respect to its ability to reduce a series of 3- through 5-carbon 2-alkanones and aldehydes of relevance as biofuel precursors. Although active on all substrates tested, LbADH displays a marked preference for longer chain substrates. Interestingly, however, 2-alkanones were found to impose substrate inhibition towards LbADH, whereas aldehyde substrates rendered no such effect. Inhibition caused by 2-alkanones was furthermore found to intensify with increasing chain length. Despite demonstrating both primary and secondary ADH activities, a preliminary sequence analysis suggests that LbADH remains distinct from other, previously characterized primary-secondary ADHs. In addition to further characterizing the substrate range of this industrially important enzyme, this study suggests that LbADH has the potential to serve as a useful enzyme for the engineering of various novel alcohol biofuel pathways.
Instabilities in Capacitively Coupled Radio-Frequency Discharges (2008)

<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> Instabilities in an asymmetric capacitively coupled radio-frequency discharge are observed at pressures above 100 Pa if a circular quartz glass tube is inserted into the discharge parallel to the powered electrode. The instabilities are observed with a charge-coupled-device camera as localized plasma balls. The number of these so-called plasmoids increases with increasing pressure. At different pressures, different modes are observed. </para>
Differential Chemotactic Behavior of Developing T Cells in Response to Thymic Chemokines (1998)

Differentiation-dependent thymocyte migration in the thymus may be important for T lymphopoiesis and might be regulated by thymic chemoattractants. We examined modulation of chemotactic responsiveness of thymocyte subsets during their early to late stages of development in response to 2 thymus-expressed chemokines, SDF-1 and CKβ-11/MIP-3β/ELC. SDF-1 shows chemotactic preference for immature thymocytes (subsets of triple negative thymocytes and double positive [DP] subset) over mature single positive (SP) thymocytes. CKβ-11/MIP-3β/ELC shows low chemotactic activity on the immature thymocytes, but it strongly attracts mature SP thymocytes, effects opposite to that of SDF-1. SDF-1–dependent chemoattraction of immature thymocytes is not significantly desensitized by a negative concentration gradient of CKβ-11/MIP-3β/ELC, and chemoattraction of mature SP thymocytes to CKβ-11/MIP-3β/ELC is not antagonized by SDF-1, demonstrating that these two chemokines have different chemoattractant preferences for thymocyte subsets and would probably not inhibit each other's chemotaxis in the event of microenvironmental coexpression. The chemotactic responsiveness of thymocytes and mature T cells to the 2 chemokines is respectively enhanced after selection process and migration to the spleen. These studies demonstrate the presence of thymocyte chemoattractants with differential chemotactic preference for thymocytes, a possible mechanism for thymocyte migration in the thymus.
A New Anionic Oxalamide Lauryl Succinate Sodium Sulfonate Gemini Surfactant: Microwave‐Assisted Synthesis and Surface Activities (2014)

Abstract An anionic Gemini surfactant, oxalamide lauryl succinate sodium sulfonate, was synthesized successfully through amidation, esterification and sulfonation reactions under microwave irradiation conditions by using maleic anhydride, ethylenediamine, lauryl alcohol, sodium sulfite as the starting materials. The best reaction conditions for synthesize the target product were obtained by single factor and orthogonal optimization methods. FTIR, elemental analysis and 1 H‐NMR analysis were used to confirm the chemical structure of the surfactant. The critical micelle concentration (CMC) in aqueous solution, surface tension, emulsification capacity and foaming power were determined. The critical micelle concentration and γ CMC are respectively equal to 3.5 × 10 −4 mol L −1 and 21.5 mN m −1 . It was found that microwave‐assisted synthesis is an efficient means of preparation of this anionic Gemini surfactant with shorter times and higher yields.
Monoassociation of Preterm Germ-Free Piglets with Bifidobacterium animalis Subsp. lactis BB-12 and Its Impact on Infection with Salmonella Typhimurium (2021)

Preterm germ-free piglets were monoassociated with probiotic <i>Bifidobacterium animalis</i> subsp. <i>lactis</i> BB-12 (BB12) to verify its safety and to investigate possible protection against subsequent infection with <i>Salmonella</i> Typhimurium strain LT2 (LT2). Clinical signs of salmonellosis, bacterial colonization in the intestine, bacterial translocation to mesenteric lymph nodes (MLN), blood, liver, spleen, and lungs, histopathological changes in the ileum, claudin-1 and occludin mRNA expression in the ileum and colon, intestinal and plasma concentrations of IL-8, TNF-α, and IL-10 were evaluated. Both BB12 and LT2 colonized the intestine of the monoassociated piglets. BB12 did not translocate in the BB12-monoassociated piglets. BB12 was detected in some cases in the MLN of piglets, consequently infected with LT2, but reduced LT2 counts in the ileum and liver of these piglets. LT2 damaged the luminal structure of the ileum, but a previous association with BB12 mildly alleviated these changes. LT2 infection upregulated claudin-1 mRNA in the ileum and colon and downregulated occludin mRNA in the colon. Infection with LT2 increased levels of IL-8, TNF-α, and IL-10 in the intestine and plasma, and BB12 mildly downregulated them compared to LT2 alone. Despite reductions in bacterial translocation and inflammatory cytokines, clinical signs of LT2 infection were not significantly affected by the probiotic BB12. Thus, we hypothesize that multistrain bacterial colonization of preterm gnotobiotic piglets may be needed to enhance the protective effect against the infection with <i>S.</i> Typhimurium LT2.
Reserve Li/SOC12 Battery Safety Testing (1984)

A reserve Lithium/Thionyl Chloride Battery concept is developed and undergoing feasibility testing in terms of performance, safety and abusive conditions. The feasibility of employing a battery of this type to replace thermal batteries in certain applications is demonstrated. Excellent performance of a Li/SOCl2 reserve battery is obtained across the temperature range from 0 C to +44 C. Performance improvement over the thermal battery usage is greater by a factor of 3 when discharge time and energy density are compared. Performance over an expanded temperature range is also possible. Safety and abusive testing is accomplished successfully on a series of five units. Further performance improvements can be achieved with regard to battery weight and volume reductions.
Using multirate rapid A/Ci curves as a tool to explore new questions in the photosynthetic physiology of plants (2018)

Steady-state photosynthetic CO<sub>2</sub> responses (A/C<sub>i</sub> curves) are used to assess environmental responses of photosynthetic traits and to predict future vegetative carbon uptake through modeling. The recent development of rapid A/C<sub>i</sub> curves (RACiRs) permits faster assessment of these traits by continuously changing [CO<sub>2</sub> ] around the leaf, and may reveal additional photosynthetic properties beyond what is practical or possible with steady-state methods. Gas exchange necessarily incorporates photosynthesis and (photo)respiration. Each process was expected to respond on different timescales due to differences in metabolite compartmentation, biochemistry and diffusive pathways. We hypothesized that metabolic lags in photorespiration relative to photosynthesis/respiration and CO<sub>2</sub> diffusional limitations can be detected by varying the rate of change in [CO<sub>2</sub> ] during RACiR assays. We tested these hypotheses through modeling and experiments at ambient and 2% oxygen. Our data show that photorespiratory delays cause offsets in predicted CO<sub>2</sub> compensation points that are dependent on the rate of change in [CO<sub>2</sub> ]. Diffusional limitations may reduce the rate of change in chloroplastic [CO<sub>2</sub> ], causing a reduction in apparent RACiR slopes under high CO<sub>2</sub> ramp rates. Multirate RACiRs may prove useful in assessing diffusional limitations to gas exchange and photorespiratory rates.
Introducing quality-of-service and traffic classes into wireless mobile networks (1998)

Article Free Access Share on Introducing quality-of-service and traffic classes into wireless mobile networks Authors: Jarkko Sevanto Nokia Research Center, P.O. Box 407 (Heikkiläntie 7) FIN-00045 NOKIA GROUP, Finland Nokia Research Center, P.O. Box 407 (Heikkiläntie 7) FIN-00045 NOKIA GROUP, FinlandView Profile , Mika Liljeberg University of Helsinki, Department of Computer Science, P.O. Box 26 (Teollisuuskatu 23), FIN-00014 University of Helsinki, Finland University of Helsinki, Department of Computer Science, P.O. Box 26 (Teollisuuskatu 23), FIN-00014 University of Helsinki, FinlandView Profile , Kimmo Raatikainen University of Helsinki, Department of Computer Science, P.O. Box 26 (Teollisuuskatu 23), FIN-00014 University of Helsinki, Finland University of Helsinki, Department of Computer Science, P.O. Box 26 (Teollisuuskatu 23), FIN-00014 University of Helsinki, FinlandView Profile Authors Info & Claims WOWMOM '98: Proceedings of the 1st ACM international workshop on Wireless mobile multimediaOctober 1998 Pages 21–29https://doi.org/10.1145/288338.288358Published:01 October 1998Publication History 3citation507DownloadsMetricsTotal Citations3Total Downloads507Last 12 Months16Last 6 weeks8 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Three Algebraic Methodsfor ConstructingNonbinary LDPCCodes basedon Finite Fields (2008)

In this paper, we present three algebraic methods for constructing structured nonbinary LDPC codes over finite fields, among which the first method is used to construct quasi-cyclic codes with girth at least 6 based on the automorphisms of finite fields, the second method gives a class of (4, p) quasi-cyclic codes with girth at least 8, the third method gives a class of codes with cycles limited. Simulation results show that the constructed codes perform very well over AWGN channel, and they have better performances or far lower computational complexities than the corresponding random Mackay codes or codes algebraically constructed by Lin. Keywords-nonbinaryLDPCcodes; finite fields; automorphism; Cycles-LimitedLDPCcodes
Tiludronate and etidronate in Paget's disease of bone: a comparative prospective double-blind multicenter study (1994)

peer reviewed
Embrittlement Behavior of Isothermally Heat-Treated T/P92 Steel at 350°C (2007)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
Effect of Carbon Nanotubes on the Behavior of the Nanocomposites TiNb/CNTs and its Weldability with TA6V by Spark Plasma Sinter for Orthopedic Application (2019)

Badis Bendjemi*1,2, Mohamed Mouyane3, Jérôme Bernard3 and David Houivet3 and Jacques G Noudem4 Author Affiliations 1DGM-FST-University of GUELMA, Guelma 2LASEA, DC-FS-University of Badji-Mokhtar-Annaba, Algeria 3LUSAC, France 4ENSICAEN, France Received: March 19, 2019 | Published: March 29, 2019 Corresponding author: Badis Bendjemil, avenue 19 Mai 1956, CS 401, 24000 Guelma, Algeria DOI: 10.26717/BJSTR.2019.16.002871
Envelope V3 Region Sequences of Cuban HIV-1 Isolates (1995)

The origin of HIV-1 species, responsible for the AIDS epidemic in Cuba, is a subject that has been intensely debated. This study represents an initial attempt to shed light on this issue, through sequence analysis of the V3 regions of viruses isolated from 15 Cuban subjects. We now report that these viruses fall within three distinct, well-recognized groupings. These findings suggest that viruses of different sources are responsible for the HIV/AIDS epidemic in Cuba.
Characteristics of transient otoacoustic emissions in patients with sudden idiopathic hearing loss (1993)

In a prospective study of 24 patients hospitalized with sudden idiopathic hearing loss syndrome (SIHLS), tonal audiometry was conducted first at an early stage after onset (Day O), again a second time (Day A, mean = 4.12 days), and again a third time (Day B, mean = 8.71 days). Transient evoked otoacoustic emissions (TEOAE) were recorded on Days O and A elicited by click stimulation. The question under investigation was whether TEOAE presence, TEOAE amplitude or peak amplitudes for the various 200-Hz-wide bands on Day O could be exploited to assess cochlear function, as indicated by pure-tone audiometry on Days A and B. The TEOAE amplitude on Day O was found to be correlated with improvement in tone threshold on Day B at 2 kHz. One significant correlation emerged between the band amplitude on Day O and the audiometric frequency improvement: on Day B between peak amplitude at 1.2 kHz and 1 kHz frequency improvement. From these results, TEOAE could theoretically be a means to assess cochlear functioning during SIHLS for 1 and 2 kHz frequencies. However, correlations are too weak to form the basis of any predictive test that could be clinically useful.
Supplementary methods and figures. from Subtypes of HPV-Positive Head and Neck Cancers Are Associated with HPV Characteristics, Copy Number Alterations, PIK3CA Mutation, and Pathway Signatures (2023)

Supplementary methods and figures. from Subtypes of HPV-Positive Head and Neck Cancers Are Associated with HPV Characteristics, Copy Number Alterations, PIK3CA Mutation, and Pathway Signatures
Analysis of gonadotrophin‐releasing hormone‐1 and kisspeptin neuronal systems in the nonphotoregulated seasonally breeding eastern rock elephant‐shrew (Elephantulus myurus) (2018)

Of the 18 sub-Saharan elephant-shrew species, only eastern rock elephant-shrews reproduce seasonally throughout their distribution, a process seemingly independent of photoperiod. The present study characterizes gonadal status and location/intensity of gonadotrophin-releasing hormone-1 (GnRH-1) and kisspeptin immunoreactivities in this polyovulating species in the breeding and nonbreeding seasons. GnRH-1-immunoreactive (ir) cell bodies are predominantly in the medial septum, diagonal band, and medial preoptic area; processes are generally sparse except in the external median eminence. Kisspeptin-ir cell bodies are detected only within the arcuate nucleus; the density of processes is generally low, except in the septohypothalamic nucleus, ventromedial bed nucleus of the stria terminalis, arcuate nucleus, and internal and external median eminence. Kisspeptin-ir processes are negligible at locations containing GnRH-1-ir cell bodies. The external median eminence is the only site with conspicuously overlapping distributions of the respective immunoreactivities and, accordingly, a putative site for kisspeptin's regulation of GnRH-1 release in this species. In the nonbreeding season in males, there is an increase in the rostral population of GnRH-1-ir cell bodies and density of GnRH-1-ir processes in the median eminence. In both sexes, the breeding season is associated with increased kisspeptin-ir process density in the rostral periventricular area of the third ventricle and arcuate nucleus; at the latter site, this is positively correlated with gonadal mass. Cross-species comparisons lead us to hypothesize differential mechanisms within these peptidergic systems: that increased GnRH-1 immunoreactivity during the nonbreeding season reflects increased accumulation with reduced release; that increased kisspeptin immunoreactivity during the breeding season reflects increased synthesis with increased release.
Imaging of Precision Therapy for Lung Cancer: Current State of the Art (2019)

Advances in characterization of molecular and genomic abnormalities specific to lung cancer have made precision therapy the current standard of care for lung cancer treatment. This article will provide a cutting-edge review of imaging of lung cancer in the current era of precision medicine. The focus of the article includes <i>(a)</i> an update on the recent advances in precision therapy for non-small cell lung cancer and their implications on imaging; <i>(b)</i> molecular and genomic biomarkers and pitfalls of image interpretations for lung cancer precision therapy; and <i>(c)</i> review of the current approaches and future directions of precision imaging for lung cancer, emphasizing emerging observations in longitudinal tumor kinetics, radiomics, and molecular and functional imaging. The article is designed to help radiologists to remain up to date in the rapidly evolving world of lung cancer therapy and serve as key members of multidisciplinary teams caring for these patients.
5-Nitro-8-quinolinols and their copper(II) complexes. Implications of the fungal spore wall as a possible barrier against potential antifungal agents (1969)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT5-Nitro-8-quinolinols and their copper(II) complexes. Implications of the fungal spore wall as a possible barrier against potential antifungal agentsHerman Gershon, Maynard W. McNeil, and Yvonne J. HindsCite this: J. Med. Chem. 1969, 12, 6, 1115–1117Publication Date (Print):November 1, 1969Publication History Published online1 May 2002Published inissue 1 November 1969https://pubs.acs.org/doi/10.1021/jm00306a042https://doi.org/10.1021/jm00306a042research-articleACS PublicationsRequest reuse permissionsArticle Views66Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts