gebhart/patrepeval huggingface dataset:
Supplementary Figure from Dynamic Changes in the NK-, Neutrophil-, and B-cell Immunophenotypes Relevant in High Metastatic Risk Post Neoadjuvant Chemotherapy–Resistant Early Breast Cancers (2023)

Supplementary Figure from Dynamic Changes in the NK-, Neutrophil-, and B-cell Immunophenotypes Relevant in High Metastatic Risk Post Neoadjuvant Chemotherapy–Resistant Early Breast Cancers
Supplementary Figure Legends 1-3 from Lowering Bone Mineral Affinity of Bisphosphonates as a Therapeutic Strategy to Optimize Skeletal Tumor Growth Inhibition <i>In vivo</i> (2023)

Supplementary Figure Legends 1-3 from Lowering Bone Mineral Affinity of Bisphosphonates as a Therapeutic Strategy to Optimize Skeletal Tumor Growth Inhibition &lt;i&gt;In vivo&lt;/i&gt;
Optimal Training Design for Channel Estimation in Amplify and Forward Relay Networks (2007)

In this paper, we study training based channel estimation for relay networks using the amplify-and-forward (AF) transmission scheme. We first point out that separately estimating the channel from source to relay and the channel from relay to destination incurs several problems. We then propose a new estimation scheme that directly estimates the overall channel from source to destination. The proposed channel estimation well matches the AF based space time coding that was developed recently. Both linear least-square estimator and minimum mean- square-error estimator are studied. The corresponding optimal training sequences and the optimal precoding matrices are also derived.
Cladonia furcata polysaccharide induced apoptosis in human leukemia K562 cells. (2001)

CFP-1 induced apoptosis in human leukemia K562 cells.
Status of Superconducting Quarter Wave Resonator Development at MHI (2016)

MHI's activities for development of Superconducting Quarter Wave Resonator (QWR) are reported. MHI has experiences of developments and fabrications of several superconducting ellipse cavities. And now MHI is developing the superconducting QWR for heavy ion accelerators.
An error model for inter-vehicle communications in highway scenarios at 5.9GHz (2005)

The design and evaluation of Inter-Vehicle Communication (IVC) protocols rely much on the accurate and efficient computational simulations. For simulations of Medium Access Control (MAC) and higher layers, the modeling work of underlying Physical layer (PHY) and wireless channel has impacts both on the computational efficiency of simulations and on the correctness of results. In this contribution, we discuss the modeling issues of the inter-vehicle wireless channel in highway scenarios and the packet error performance of Dedicated Short Range Communications (DSRC) PHY, which works at the newly allocated 5.9GHz Intelligent Transportation System (ITS) frequency band. A computationally efficient yet accurate enough error modeling approach used in our MAC layer simulator WARP2 is presented in this paper, together with simulation results. Both weaknesses and potential improvements of the proposed approach are discussed also in this work.
Structural Modifications in Amorphous Oxide Nanolaminates with Annealing (2022)

Nanolaminates of TiO 2 /Ta 2 O 5 , SiO 2 /Ta 2 O 5 and TiO 2 /GeO 2 are investigated to assess structural modifications with annealing. Depending on the nanolaminate composition, annealing is shown to enhance cation diffusion.
State of the art in construction simulation (1992)

This paper addresses the state-of-the-art in construction simulation.
Interrogating patient-centredness in undergraduate medical education using an integrated behaviour model (2017)

Background: Patient-centredness, an approach that puts the patient at the centre of the consultation, thus focusing on patients instead of on his/her diseases, has been identified by most medical schools as a desired core competence of their graduates. Despite some curriculum initiatives, medical students often display a lack of patient-centredness upon graduation. This bears reason for concern and it was thus deemed important to explore possible factors that influence the teaching and learning of patient-centredness in an undergraduate medical curriculum. The article suggests a framework that can assist programme developers to conceptualise the teaching and learning of patient-centredness across an undergraduate curriculum.Methods: A qualitative exploratory case study design was used for the study with final-year medical students. Themes of meaning were deduced from the data by employing components of an Integrated Behavior Model (IBM) of Fishbein.Results: The findings of the study revealed that seven factors play a role: background characteristics of students, attitudinal factors, subjective norms (the hidden curriculum), student self-efficacy, acquired skills and knowledge, the environment or context within which patient-centredness is taught and learnt, as well as assessment of learning.Conclusions: Patient-centredness is a complex construct and authors often write about only one of its components. This paper attempts to consider the total undergraduate medical curriculum students are exposed to when they learn about being patient-centred. The teaching and learning of such a multidimensional construct require a comprehensive approach in order to be effective and the IBM seems to be a useful and applicable theoretical model to apply.
Inhibition of platelet aggregation by the GPIIb/IIIa antagonist Reopro does not significantly prolong xenograft survival in an ex vivo model (1999)

Effects on hyperacute rejection were studied in a discordant model with the platelet GPIIb/IIIa antagonist Reopro. Pig kidneys perfused with human blood survived median 118 min in the Reopro group and 103 min in the controls (P= 0.22). Platelet and leukocyte counts decreased, whereas plasma thrombospondin and soluble as well as platelet membrane P-selectin increased significantly in both groups without significant intergroup differences. β-Thromboglobulin and myeloperoxidase increased significantly more in the control group than in the Reopro group (P - 0.009 and P - 0.02, respectively). The classical complement pathway was substantially and similarly activated in both groups. Light and electron microscopy revealed arterial thrombi and numerous glomerular platelet aggregates in the control group in contrast to the Reopro group. In conclusion, Reopro reduced platelet aggregation, and platelet and leukocyte activation to some extent, but had no effect on complement activation and did not significantly prolong xenograft survival, even though better preservation of morphology was shown.
Cytochrome P450 immobilisation as a route to bioremediation/biocatalysis (1998)

The diverse substrate specificity of the cytochrome P450 (P450; CYP) enzyme superfamily offers the opportunity to develop enzymatic systems for environmental detoxification and biotransformations of drugs, pesticides and fine chemicals. Here we report on the immobilisation of a fusion protein between plant cytochrome P450-71B1 (CYP71B1) and its electron donor, plant NADPH cytochrome P450 reductase using an oil-in-water macro-emulsion, termed polyaphron, which contains a proportion of internal organic phase (phi) greater than 0.74. Efficiency of P450 immobilisation was greater than 85%, and in this state enzymatic activity could be measured for more than 24 h at 15 degrees C. Chlortoluron, a recalcitrant herbicide pollutant in the environment, was shown to be metabolised, with the major metabolite (N-monodemethylated chlortoluron) being separated from the substrate due to partitioning into the aqueous phase. The turnovers exhibited superactivity compared with those obtained using free enzyme located in membranes prepared following heterologous expression in Saccharomyces cerevisiae and Escherichia coli. The potential to exploit the unprecedented catalytic diversity of the P450 superfamily in biocatalysis is discussed.
Parallel Network Dual Simplex Method on a (1993)

We Present a parallel algorithm for solving the dual transshipment problem [l I. The traditional dual simplex method does not offer much scope for parallelization, because it moves from one basic feasible solution to another, performing one pivot operation at a time. We present a new method called Mod@ed Network Dual Simpler method which uses concurrent pivots. This departure from the traditional LP approach raises several issues such as the need to convert a non-basic feasible solution to a basic feasible solution. We present our strategies to handle these issues as well as the corresponding parallel algorithms. We also present results of testing this algorithm on large graphs to solve the integrated layout compaction and wire balancing problem.
Planning multi-paths using speciation in genetic algorithms (2002)

A path planning algorithm is developed based on a minimal representation size cluster genetic algorithm (MRSC GA). The algorithm utilizes evolutionary computation techniques for planning paths for mobile robots, piano-movers problems and N-link manipulators. MRSC GA is used for generating multi-paths to provide alternative solutions to the path planning problem. The generation of alternative solutions is especially important for planning paths in dynamic environments. A novel iterative multi-resolution path representation is used as a basis for the GA coding. The effectiveness of the algorithm is demonstrated on a number of 2D path planning problems.
Clinical parameters for determining when and when not to treat essential thrombocythemia. (1999)

Essential thrombocythemia (ET) is a myeloproliferative disorder that occurs primarily in middle-aged adults. ET is relatively benign compared with some of the other myeloproliferative disorders (MPDs), but there is still a high rate of morbidity and quality of life can be affected, especially by thrombotic and hemorrhagic complications. Two thirds of ET patients are symptomatic, but therapies are not benign. While alkylating agents, radioactive phosphorous, and hydroxyurea (HU) all have a leukemogenic risk, their use in high-risk and elderly patients may still be warranted in some circumstances. Use of nonmutagenic agents such as anagrelide, interferon-alpha (IFN), or low-dose aspirin has become an attractive alternative. However, the risks and benefits of treatment versus nontreatment should be based on clinical data and must be determined on an individual basis.
Characterizing Nonrigid Aggregated Soil–Water Medium Using its Shrinkage Curve (2004)

The properties of the soil–water medium are presented in the literature independent of its internal organization and operation. The objective of this study is to develop and test a conceptual model that used a continuously measured shrinkage curve (SC) to describe the functional organization of the soil–water medium. In this model, two functional porosities (micro and macro) are delineated and quantified by the SC. In addition, the equilibrium for four functional water pools is represented and parameterized by the SC. A set of eleven parameters was found necessary to model the seven phases of the SC and to describe the corresponding soil hydrostructural changes. A method to accurately obtain the parameters of this model by a specific analysis of the continuously measured SC is demonstrated. Examples of continuously measured and modeled SCs according to the pedostructure model (PS) are presented and discussed.
Attacking the baseband modem of mobile phones to breach the users' privacy and network security (2015)

As people are using their smartphones more frequently, cyber criminals are focusing their efforts on infecting smartphones rather than computers. This paper presents the design and implementation of a new type of mobile malware, named (U)SimMonitor for Android and iPhone devices, which attacks the baseband modem of mobile phones. In particular, the mobile malware is capable of stealing security credentials and sensitive information of the cellular technology including permanent and temporary identities, encryption keys and location of users. The developed malware operates in the background in a stealthy manner without disrupting the normal operation of the phone. We elaborate on the software architecture of (U)SimMonitor and provide implementation details for the specific AT commands used by the malware. We analyse the security impacts of (U)SimMonitor malware and we show that it can entirely breach the privacy of mobile users and the security of cellular networks. In particular, a mobile user with an infected phone can be identified and all his/her movements can be tracked. Moreover, all his/her encrypted phone calls and data sessions can be disclosed.
The Gamma nail for peritrochanteric fractures (1992)

The Gamma nail was designed to treat unstable intertrochanteric and subtrochanteric fractures. The device was developed after cadaver studies and has been used clinically since February 1985 in a total of 421 patients. The results in 123 patients treated by the third version of this design are reported. The Gamma nail transmits weight closer to the calcar than does the dynamic hip screw and it has greater mechanical strength. A semi-closed operative technique is used, with an average duration of operation of 35 minutes and little blood loss. Distal locking screws can be used to maintain rotational stability, and can be inserted without the use of an image intensifier. Results showed satisfactory fracture union with little loss of position, even in comminuted fractures. Operative complications were few, but included fractures of the base of the greater trochanter. The most important postoperative complication, seen in one case, was fracture of the shaft of the femur at the distal end of the nail, but this healed well after re-nailing.
Induction of tooth and eye by transplantation of activin A-treated, undifferentiated presumptive ectodermal Xenopus cells into the abdomen (2004)

Activin A can induce the Xenopus presumptive ectoderm (animal cap) to form different types of mesoderm and endoderm at different concentrations and the animal cap treated with activin can function as an organizer during early development. The dissociated Xenopus animal cap cells treated with activin form an aggregate and it develops into various tissues in vitro. In this study, to induce jaw cartilage from undifferentiated cells effectively, we developed a culture method to manipulate body patterning in vitro, using activin A and dissociated animal cap cells. An aggregate consisting only of activin A-treated dissociated cells developed into endodermal tissues. However, when activin A-treated cells were mixed with untreated cells at a ratio of 1:5, the aggregate developed cartilage with the maxillofacial regional marker genes, goosecoid, Xenopus Distal-less 4 and X-Hoxa2. When this aggregate was transplanted into the abdominal region of host embryos, maxillofacial structures containing cartilage and eye developed. We raised these embryos to adulthood and found that tooth germ had developed in the transplanted tissue. Here, we show the induction of jaw cartilage, tooth germ and eye structures from animal caps using activin A in the aggregation culture method. This differentiation system will help to promote a better understanding of the regulating mechanisms of body patterning and tooth induction in vertebrates.
Carbon‐Coated Nanophase CaMoO4 as Anode Material for Li Ion Batteries. (2004)

Abstract For Abstract see ChemInform Abstract in Full Text.
The Fate of Grafting Acetabular Defects During Revision Total Hip Arthroplasty (2010)

Higher degrees of defect fill and healing were seen with complete revisions compared to head/liner exchanges. Compared to CT scans, plain radiograph assessment tended to overestimate defect fill and healing.
Whole Field Measurement of Temperature in Water Using Two-Color Laser Induced Fluorescence (1997)

A technique is described that measures the instantaneous three-dimensional temperature distribution of water using two-color laser-induced fluorescence (LIF). Two fluorescent dyes, Rhodamine Band Rhodamine 110, are used as temperature indicators. A laser light sheet scanned across the entire measurement volume excites the fluorescent dye, and an optical system involving a color beam splitter gives the intensity distribution of the individual fluorescent dyes on two separate monochrome CCD cameras. The ratio of these fluorescence intensities at each point of the image is calibrated against the temperature to eliminate the effect of the fluctuation of illuminating light intensity. A stable thermally stratified layer was measured by this system to evaluate the total accuracy of the measurement system. The random error of the measurement was ±l.4K with 95% confidence. Measurements of thermal convection over a heated horizontal surface show temperature isosurfaces having typical structures such as plumes, ridges and thermals.
Detecting Specular Reflections Using Lambertian Constraints (2005)

Specularities-briglit image regions formed by specular reflectioir-are likely to be mistalien for genuine surface ma,rking.j by processes that perform photometric analysis, derive motion fields from optical flow or estimate depth from binocular stereo. In addit8iori they can be uscd to infer surface geometry. This paper describes a scheme for detecting specularities based 011 a cliaracterisatioil of Larnbertian surfaces. Real surfaces are not simple composites of Lambertiaii and specular sur- faces hut evidence suggests that away from specrilnrities they do not deviate from the Lainbertian model by more than a factor of 3 or so. This proves adequate to serve as a constraint for specularity detection. Two independent tests identify iinage regions where tlie constraint is violated. Tlie detector is shown to performs well on a varicty of real images. Applications: improving binocular stereo and inferring surface geometry are described using specularities produced by the detector. ACI(NOWLEI)GEI\IENTS: Work done at:L)ept. Conip. Sci, TJniv. Edin- burgh; Studenthip: (gjh) IDM UKSC & SERC; Grant Pics: AIVRU Sliefield; IIelp: A.Zisserinan&C.hlarinos.
Differences in Vascular Nitric Oxide and Endothelium-Derived Hyperpolarizing Factor Bioavailability in Blacks and Whites (2014)

http://clinicaltrials.gov/. Unique identifier: NCT00166166.
An explicit formula for optical oscillator strength of excitons in semiconducting single-walled carbon nanotubes: family behavior (2013)

The sensitive structural dependence of the optical properties of single-walled carbon nanotubes, which are dominated by excitons and tunable by changing diameter and chirality, makes them excellent candidates for optical devices. Because of strong many-electron interaction effects, the detailed dependence of the optical oscillator strength fs of excitons on nanotube diameter d, chiral angle θ, and electronic subband index P (the so-called family behavior), however, has been unclear. In this study, based on results from an extended Hubbard Hamiltonian with parameters derived from ab initio GW plus Bethe–Salpeter equation (GW-BSE) calculations, we have obtained an explicit formula for the family behavior of the oscillator strengths of excitons in semiconducting single-walled carbon nanotubes (SWCNTs), incorporating environmental screening. The formula explains recent measurements well and is expected to be useful in the understanding and design of possible SWCNT optical and optoelectronic devices.
Association between the geographic region and the risk of familial atrioventricular nodal reentry tachycardia in the Polish population (2021)

Introduction: Atrioventricular nodal reentrant tachycardia (AVNRT) is one of the most common regular supraventricular arrhythmias referred for catheter ablation (CA). In Poland, several families with familial AVNRT (FAVNRT) were reported in Podkarpacie Province (PP). Objectives: We aimed to determine the frequency of FAVNRT in PP compared with other south-eastern provinces of Poland. Patients and methods: Clinical data of 1544 patients with AVNRT diagnosed by invasive electrophysiological study between 2010 and 2019 were screened for FAVNRT. From January 2017 to June 2019, patients were asked to provide details on family history and origin to obtain 3-generation pedigrees. Families with at least 2 members with previous CA of AVNRT were divided into those from south-eastern provinces (SEPs; including PP and bordering provinces [BPs]) and the remaining parts of Poland (RPP). Results: There were 932 patients from SEPs and 612 from RPP. FAVNRT was reported in 45 patients (2.91%) from 27 families, with a higher frequency in SEPs than RPP (4.02% vs 1.17%; P = 0.002) and the highest frequency in PP (6.33% vs 2.47% in BPs; P = 0.004). The risk of FAVNRT was higher in PP compared with BPs (odds ratio, 2.67; 95% CI, 1.36–5.23; P = 0.004) and similar in BPs compared with RPP (odds ratio, 2.14; 95% CI, 0.86–5.34; P = 0.1). Conclusions: A relationship exists between the geographic region and frequency of FAVNRT. A greater distance from PP was associated with less frequent FAVNRT. International cooperation and genetic testing are needed to confirm the genetic impact of FAVNRT in this part of Central Europe.
Origin of 6-fold coordinated aluminum at (010)-type pyrophyllite edges (2017)

To better understand the aqueous chemical reactivity of clay mineral edges we explored the relationships between hydration and the structure of (010)-type edges of pyrophyllite. In particular, we used density functional theory and the quantum theory of atoms in molecules to evaluate the stability of 6-fold coordinated hydrated aluminum at the edge in terms of the electron density distribution. Geometrical optimization revealed an intra-edge hydrogen bond network between aluminol hydroxyls and water ligands completing the aluminum coordination shell. From the electron density isosurfaces one water ligand is not covalently bonded to aluminum. Bader charge analysis revealed that OH2 ligands have small negative charge. In addition, it is also found that the charge of the 6-fold coordinated aluminum is larger than one of the 5-fold aluminum. From these results, the charging of the OH2 ligands is interpreted as charge transfer originated from the formation of the hydrogen bond network and not from Al-OH2 interaction per se. This suggests that the weakly bound water ligand in question, and more generally 6-fold hydrated edge Al coordination, is stabilized primarily by the hydrogen bond network which in turn leads to weak ionic attraction to the aluminum center itself. The finding highlights the importance of cooperative effects between solvent structure and the coordination of metal cations exposed at clay mineral edges.