gebhart/patrepeval huggingface dataset:
Hand tracking and pose recognition via depth and color information (2012)

As one of the most natural and intuitive way of communication between people and machines, hand gesture is widely used in HCI (Human-Computer-interaction). In this paper, we proposed a novel method for hand tracking and pose recognition based on Kinect. For hand tracking, skin information is used for initialization of hand segmentation, and then a region growing algorithm is applied in the depth image to separate hand from other skin colored objects. Finally, a Kalman filter is used for tracking hand in 3D space. For hand recognition, we decompose the problem of recognizing hand pose into recognizing different finger states. Both contour information of the whole hand and depth information inside the contour are considered for finger states recognition. It is shown in the experiments that our system can track the hand robustly and recognize more than 90% of the hand poses we define for our depth image database.
A Radon Progeny Sampler for the Determination of Effective Dose (1997)

The design and simulated performance is described of a two-stage sampler (HE-Sampler) for 222Rn progeny. This HE-Sampler has a collection efficiency optimised to match the particle size dependency of the radon progeny dose conversion factor (DCF), derived from the latest Respiratory Tract Model of the International Commission on Radiological Protection, as implemented in the computer code RADEP. The HE-Sampler comprises a wire screen pre-Separator, matched to the nasal deposition, and a wire screen collector, matched to the respiratory tract collection. This HE-Sampler allows for the estimation of the radiation dose from the inhalation of 222Rn progeny, derived from two concurrent alpha particle activity measurements, one on the HE-Sampler screen collector and one on a reference filter sample. As a first approximation, the DCF is proportional to the collected fraction. The HE-Sampler response was simulated for a range of radon progeny size distributions to determine the error in the estimated DCF values. For monodispersed radon progeny the DCF errors were up to 35%. For polydispersed radon progeny distributions in the range 1 nm to 1000 nm, the DCF error was in the range �10% and �20%, for occupational and environmental exposure, respectively. This error range can be reduced to �10% between 0.6 nm and 700 nm by using a data set of 70 experimental measurements taken as representative of environmental and occupational exposure. For environmental exposure, the derived mean DCF error and the root mean square error were +3.6% and �4.8% for polynomial fitting functions, respectively. The corresponding values for occupational exposure were 0.5% and �3.1%. The effect of systematic errors in the operating parameters was investigated using a further simulation based on this experimental data set. The simulation results show that the HE-Sampler is relatively insensitive to variations in sampling rate and in the screen parameters, particularly for environmental exposure.
Preservation of quail blastoderm cells in liquid nitrogen (1992)

1. Quail blastoderm cells isolated from the yolk were preserved in liquid nitrogen. 2. Frozen-thawed blastoderm cells of the quail were viable and survived in vitro. By injecting the frozen-thawed cells into chick embryos, quail-chick chimaeras were produced.
Side Channel Attacks on Implementations of Curve-Based Cryptographic Primitives. (2005)

The present survey deals with the recent research in side channel analysis and related attacks on implementations of cryptographic primitives. The focus is on software contermeasures for primitives built around algebraic groups. Many countermeasures are described, together with their extent of applicability, and their weaknesses. Some suggestions are made, conclusion are drawn, some directions for future research are given. An extensive bibliography on recent developments concludes the survey.
Phase II trial of weekly paclitaxel and concurrent radiation therapy for locally advanced non-small cell lung cancer. (1998)

We conducted a prospective Phase II study to determine the response rate, toxicity, and 2-year survival rate of concurrent weekly paclitaxel and radiation therapy (RT) for locally advanced unresectable non-small cell lung cancer. The weekly paclitaxel regimen was designed to optimize the radiosensitizing properties of paclitaxel. Thirty-three patients with unresectable stage IIIA and IIIB non-small cell lung cancer from six institutions were entered into the study between March 1994 and February 1995. Weekly i.v. paclitaxel (60 mg/m2; 3-h infusion) plus concurrent chest RT (60 Gy over 6 weeks) was delivered for 6 weeks. Twenty-nine patients were evaluable for response. Three patients achieved a complete response (10%), and 22 patients (76%) achieved a partial response, for an overall response rate of 86% (95% confidence interval, 68-96%). One patient progressed during the therapy, and three patients had stable disease. Esophagitis was the principal toxicity. Grade 3 or 4 esophagitis occurred in 11 patients (37%). One patient died of pneumonia after completion of therapy. Additional grade > or =3 toxicities included pneumonitis (12%) and neutropenia (6%). One patient had a grade 3 hypersensitivity reaction. The median overall survival duration for all 33 patients who entered the study was 20 months, and 1-, 2-, and 3-year overall survival rates were 60.6%, 33.3%, and 18.2%, respectively. The median progression-free survival duration for all 33 patients was 10.7 months, and 1-, 2-, and 3-year progression-free survival rates were 39.4%, 12.1%, and 6.1%, respectively. Weekly paclitaxel plus concurrent RT is a well-tolerated outpatient regimen. The survival outcome from this regimen is encouraging and seems to be at least equivalent to that of other chemotherapy/radiation trials. These findings warrant further clinical evaluation of weekly paclitaxel/RT in Phase II trials in the neoadjuvant setting and in combination with other cytotoxic agents.
Measuring the surface tension of glass in the temperature region of softening and viscous flow (2003)

Based on a model of a thin-walled cylindrical tube, formulas are obtained that give a quantitative description of the shrinkage of microcapillary structures when they are heated. The resulting formulas establish the interconnection between the geometrical parameters of microcapillaries and the rates at which they shrink with the viscosity and surface tension of the glass from which they are fabricated. That is, on the basis of experimental data on the shrinkage rates of microcapillaries in the radial and axial directions, a new method has been developed for measuring the surface tension of glass in the high-viscosity state all the way to the softening and glass-annealing temperatures. The temperature gradient of the surface tension in this interval is much greater than the analogous data obtained for the melting of glass.
Proton radiation response of SiGe HBT analog and RF circuits and passives (2001)

Presents the first experimental results of the effects of 63 MeV proton irradiation on SiGe heterojunction bipolar transistor (HBT) analog and radio-frequency (RF) circuits and passive elements. A SiGe HBT bandgap, reference circuit, commonly used to generate stable on-chip voltages in analog ICs, a SiGe HBT voltage-controlled oscillator, a key building block for RF transceivers, and an LC bandpass filter routinely used in RF circuit design were each irradiated to proton fluences as high as 5/spl times/10/sup 13/ p/cm/sup 2/. The degradation associated with these extreme proton fluences was found to be minimal, suggesting that SiGe HBT technology is robust for these types of circuit applications.
Lightweight Monocular Depth with a Novel Neural Architecture Search Method (2021)

This paper presents a novel neural architecture search method, called LiDNAS, for generating lightweight monocular depth estimation models. Unlike previous neural architecture search (NAS) approaches, where finding optimized networks are computationally highly demanding, the introduced novel Assisted Tabu Search leads to efficient architecture exploration. Moreover, we construct the search space on a pre-defined backbone network to balance layer diversity and search space size. The LiDNAS method outperforms the state-of-the-art NAS approach, proposed for disparity and depth estimation, in terms of search efficiency and output model performance. The LiDNAS optimized models achieve results superior to compact depth estimation state-of-the-art on NYU-Depth-v2, KITTI, and ScanNet, while being 7%-500% more compact in size, i.e the number of model parameters.
The Novel Highly Lipophilic Topoisomerase I Inhibitor DB67 Is Effective in the Treatment of Liver Metastases of Murine CT-26 Colon Carcinoma (2004)

Colorectal carcinoma occurs in 1 of 20 individuals in most developed countries. The relapse after resection with metastatic liver disease is a major cause of death. 7-t-Butyldimethylsilyl-10-hydroxycamptothecin (DB67) has been incorporated into liposomes allowing for intravenous (i.v.) administration. A preclinical efficacy study of liposomal DB67 was performed using the colon carcinoma CT-26 cell line. The therapeutic dose for DB67 and liposomal DB67 was found to be 7 mg/kg per day using the qdx5/1 schedule. The results are compared with those obtained with irinotecan. The treatment with liposomal DB67 administered intravenously was more effective in reducing the weight and volume of primary spleen tumors and the weight and extent of liver metastases than free DB67 or liposomal DB67 administered intraperitoneally, but less effective than irinotecan. When the primary tumor was resected, treatment with liposomal DB67 administered intravenously was more effective in reducing the weight and extent of liver metastases than DB67 or liposomal DB67 administered intraperitoneally, and irinotecan. DB67 showed a higher accumulation in spleen and liver after its i.v. administration in liposomal form compared with its free or liposomal form administered intraperitoneally. DB67 and liposomal DB67 are more effective than irinotecan in the treatment of liver metastases after resection of the primary tumor.
Macular pigment and macular volume in eyes of patients with cystic fibrosis (2014)

Unsupplemented CF patients have markedly lower levels of macular carotenoids (e.g., lutein and zeaxanthin), but well-maintained visual function and no significant reductions in central MV primarily composed of macular photoreceptors. Future studies are needed to determine whether the lifelong decrease in protective central retinal carotenoids predisposes CF patients to later-life retinal pathology.
Reaction of o-, m- and p-Acetotoluidide with 2-Propanol in Concentrated Sulfuric Acid (1968)

The reaction of o-, m- and p-acetotoluidide with 2-propanol was studied in concentrated sulfuric acid. By the isopropylation of p-acetotoluidide two substances were produced : 4-methyl-3, 5-(I) and 4-methyl-2, 5-diisopropylacetanilide (II). From o- and m-isomers arose 2-methyl-3, 5-(XI) and 5-methyl-2, 4-diisopropylacetanilide (VI) respectively. The structures of the products were determined by bromination of corresponding aniline derivatives which were obtained by acid hydrolysis of isopropylation products. IR and NMR spectra of the products were also measured to get further evidences on the structures. The isopropylation reaction of acetotoluidides in concentrated sulfuric acid proceeded under the orientation of alkyl rather than acetamide substituents.
Shear instability of nanocrystalline silicon carbide during nanometric cutting (2012)

The shear instability of the nanoscrystalline 3C-SiC during nanometric cutting at a cutting speed of 100 m/s has been investigated using molecular dynamics simulation. The deviatoric stress in the cutting zone was found to cause sp3-sp2 disorder resulting in the local formation of SiC-graphene and Herzfeld-Mott transitions of 3C-SiC at much lower transition pressures than that required under pure compression. Besides explaining the ductility of SiC at 1500 K, this is a promising phenomenon in general nanoscale engineering of SiC. It shows that modifying the tetrahedral bonding of 3C-SiC, which would otherwise require sophisticated pressure cells, can be achieved more easily by introducing non-hydrostatic stress conditions.
Burst Mode Receiver for 112 Gb/s DP-QPSK with parallel DSP (2011)

A burst mode 112 Gb/s DP-QPSK digital coherent optical receiver with parallel DSP suitable for implementation in a CMOS ASIC with a 218.75 MHz clock speed is presented. The receiver performance is validated in a five channel 50 GHz grid WDM burst switching experiment using a commercially available wavelength tunable laser as the local oscillator. A new equalizer initialization scheme that overcomes the degenerate convergence problem and ensures rapid convergence is introduced. We show that the performance of the tunable local oscillator is commensurate with burst mode coherent reception when differential decoding in employed and that required parallel DSP implementation does not seriously impair the polarization and frequency tracking performance of a digital coherent receiver under burst mode operation. We report a burst acquisition time of less than 200 ns.
Alcoholic hepatitis accelerates early hepatobiliary cancer by increasing stemness and miR-122-mediated HIF-1α activation (2016)

Alcohol-related hepatocellular carcinoma (HCC) develops with advanced alcoholic liver disease and liver fibrosis. Using adult mice, we evaluate the effect of alcoholic steatohepatitis on early hepatobiliary carcinoma after initiation by diethyl-nitrosamine (DEN). Here we show that alcohol-fed DEN-injected mice have higher ALT and liver-to-body weight ratio compared to pair-fed DEN-injected mice. Alcohol feeding results in steatohepatitis indicated by increased pro-inflammatory cytokines and fibrotic genes. MRI and liver histology of alcohol+DEN mice shows hepatobiliary cysts, early hepatic neoplasia and increase in serum alpha-fetoprotein. Proliferation makers (BrdU, cyclin D1, p53) and cancer stem cell markers (CD133 and nanog) are significantly up-regulated in livers of alcohol-fed DEN-injected mice compared to controls. In livers with tumors, loss of miR-122 expression with a significant up-regulation of miR-122 target HIF-1α is seen. We conclude that alcoholic steatohepatitis accelerates hepatobiliary tumors with characteristic molecular features of HCC by up-regulating inflammation, cell proliferation, stemness, and miR-122 loss.
Data from TWEAK–Fn14–RelB Signaling Cascade Promotes Stem Cell–like Features that Contribute to Post-Chemotherapy Ovarian Cancer Relapse (2023)

&lt;div&gt;Abstract&lt;p&gt;Disease recurrence in high-grade serous ovarian cancer may be due to cancer stem–like cells (CSC) that are resistant to chemotherapy and capable of reestablishing heterogeneous tumors. The alternative NF-κB signaling pathway is implicated in this process; however, the mechanism is unknown. Here we show that TNF-like weak inducer of apoptosis (TWEAK) and its receptor, Fn14, are strong inducers of alternative NF-κB signaling and are enriched in ovarian tumors following chemotherapy treatment. We further show that TWEAK enhances spheroid formation ability, asymmetric division capacity, and expression of &lt;i&gt;SOX2&lt;/i&gt; and epithelial-to-mesenchymal transition genes &lt;i&gt;VIM&lt;/i&gt; and &lt;i&gt;ZEB1&lt;/i&gt; in ovarian cancer cells, phenotypes that are enhanced when TWEAK is combined with carboplatin. Moreover, TWEAK in combination with chemotherapy induces expression of the CSC marker CD117 in CD117&lt;sup&gt;−&lt;/sup&gt; cells. Blocking the TWEAK–Fn14–RelB signaling cascade with a small-molecule inhibitor of Fn14 prolongs survival following carboplatin chemotherapy in a mouse model of ovarian cancer. These data provide new insights into ovarian cancer CSC biology and highlight a signaling axis that should be explored for therapeutic development.&lt;/p&gt;Implications:&lt;p&gt;This study identifies a unique mechanism for the induction of ovarian cancer stem cells that may serve as a novel therapeutic target for preventing relapse.&lt;/p&gt;&lt;/div&gt;
Towards 1000-mode Optical Fibres (2022)

We report on the design of multimode-mode fibres guiding up to 870 spatial and polarization modes for low differential mode delay over the C-band.
A novel interaction between DNA ligase III and DNA polymerase γ plays an essential role in mitochondrial DNA stability (2007)

The data in the present study show that DNA polymerase gamma and DNA ligase III interact in mitochondrial protein extracts from cultured HT1080 cells. An interaction was also observed between the two recombinant proteins in vitro. Expression of catalytically inert versions of DNA ligase III that bind DNA polymerase gamma was associated with reduced mitochondrial DNA copy number and integrity. In contrast, overexpression of wild-type DNA ligase III had no effect on mitochondrial DNA copy number or integrity. Experiments revealed that wild-type DNA ligase III facilitates the interaction of DNA polymerase gamma with a nicked DNA substrate in vitro, and that the zinc finger domain of DNA ligase III is required for this activity. Mitochondrial protein extracts prepared from cells overexpressing a DNA ligase III protein that lacked the zinc finger domain had reduced base excision repair activity compared with extracts from cells overexpressing the wild-type protein. These data support the interpretation that the interaction of DNA ligase III and DNA polymerase gamma is required for proper maintenance of the mammalian mitochondrial genome.
Usage Metrics (2018)

One of the features of Power BI Service is a usage metrics report on a dashboard or report. The usage metrics report will give you an analysis of how many times the content is viewed or share, through which platforms, and by which users. You can also create your monitoring report based on the model of usage metrics. In this chapter, you’ll learn how easy it is to use the usage metrics or even create your report from it.
COMPLEX RELATIONS BETWEEN CORTICOSTEROIDS AND THE ADHESIVE STATE OF THE WHITE BLOOD CELLS IN THE PERIPHERAL BLOOD: FURTHER ANALYSIS OF THE STATE OF LEUKOCYTE/ADHESIVENESS AGGREGATION IN THE PERIPHERAL BLOOD AS A MARKER OF STRESS (1997)

Stress is associated with an increment in the concentration of cortisol, a leukocytotic response and increased state of leukocyte adhesiveness/aggregation (LAA) in the peripheral blood. We investigated the interrelationship between these three parameters in individuals under various conditions of stress. These included 123 emergency room patients with chest pain who were also classified in regard to the presence or absence of heart failure; 15 men in the fertility clinic donating semen and 16 women in the operating room before induction of anaesthesia for dilatation and curettage. A low (r=0.35) but significant (p<0.001) correlation was noted between cortisol level, leukocyte count, and per cent of aggregated leukocytes in the peripheral blood in the first group (ischaemic heart disease) but not the fertility clinic or operating room patients. A complementary study in dogs which received an intravenous hydrocortisone injection revealed neither an increased leukocyte number in the peripheral blood nor an increment in the adhesive state. In vitro studies confirmed the depressant effect of high concentrations of hydrocortisone on cell adhesiveness despite an increment in the expression of various adhesive proteins on the surface of the peripheral blood leukocytes. We concluded that the increased state of leukocyte adhesiveness noted by us in the past in patients under stress is not necessarily related to the presence of an increased cortisol concentration, and that factors other than corticosteroid level should be explored as possible triggers of the LAA response during stress. © 1997 by John Wiley & Sons, Ltd.
Mid-infrared ultra high Q factors in fluoride crystalline microresonators (2016)

Using an uncoated chalcogenide tapered fiber as a high ideality coupler, we demonstrate ultra-high quality factors deep in the mid-infrared with crystalline microres-onators. Due to low multiphonon absorption we obtain the highest mid-infrared optical finesse.
Trafficking of Dendritic Cells (2005)

This chapter contains sections titled: Introduction Dendritic Cells Langerhans Cells: The Prototype of Trafficking Dendritic Cells Pathways and Morphology of Dendritic Cell Trafficking Life Path of a Dendritic Cell from Birth to Death Trafficking from the Bone Marrow to the Tissue of Residence Egress from the Tissue of Residence, Migration Through Connective Tissue, and Entry into Lymph Vessels Arrival at the Lymphatic Organs and Entry into the T Cell Area Dendritic Cell Traffic “In the Fast Lane” Regulation of Dendritic Cell Trafficking Trafficking from the Bone Marrow to the Tissue of Residence Egress from the Tissue of Residence Relationship Between Migration and Maturation of Dendritic Cells Trafficking of Plasmacytoid Dendritic Cells Functional Implications of Dendritic Cell Trafficking Homeostasis of the Sentinel Cell Network Initiation of Immunity Maintenance of Peripheral Tolerance Application-Oriented Considerations for Immunotherapy Acknowledgments References
Glacier ice archives fifteen-thousand-year-old viruses (2020)

Abstract While glacier ice cores provide climate information over tens to hundreds of thousands of years, study of microbes is challenged by ultra-low-biomass conditions, and virtually nothing is known about co-occurring viruses. Here we establish ultra-clean microbial and viral sampling procedures and apply them to two ice cores from the Guliya ice cap (northwestern Tibetan Plateau, China) to study these archived communities. This method reduced intentionally contaminating bacterial, viral, and free DNA to background levels in artificial-ice-core control experiments, and was then applied to two authentic ice cores to profile their microbes and viruses. The microbes differed significantly across the two ice cores, presumably representing the very different climate conditions at the time of deposition that is similar to findings in other cores. Separately, viral particle enrichment and ultra-low-input quantitative viral metagenomic sequencing from ∼520 and ∼15,000 years old ice revealed 33 viral populations (i.e., species-level designations) that represented four known genera and likely 28 novel viral genera (assessed by gene-sharing networks). In silico host predictions linked 18 of the 33 viral populations to co-occurring abundant bacteria, including Methylobacterium , Sphingomonas , and Janthinobacterium , indicating that viruses infected several abundant microbial groups. Depth-specific viral communities were observed, presumably reflecting differences in the environmental conditions among the ice samples at the time of deposition. Together, these experiments establish a clean procedure for studying microbial and viral communities in low-biomass glacier ice and provide baseline information for glacier viruses, some of which appear to be associated with the dominant microbes in these ecosystems. Importance This study establishes ultra-clean microbial and viral sampling procedures for glacier ice, which complements prior in silico decontamination methods and expands, for the first time, the clean procedures to viruses. Application of these methods to glacier ice confirmed prior common microbiological findings for a new ice core climate record, and provides a first window into viral genomes and their ecology from glacier ice across two time horizons, and emphasizes their likely impact on abundant microbial groups. Together these efforts provide clean sampling approaches and foundational datasets that should enable simultaneous access to an archived virosphere in glacier ice.