gebhart/patrepeval huggingface dataset:
Mesothelial and Related Neoplasms in Children and Adolescents: A Clinicopathologic and Immunohistochemical Analysis of Eight Cases (1992)

Mesothelioma is a neoplasm that occurs infrequently in childhood; only an estimated 2-5% of all cases present in the first two decades of life. The diagnosis may be perplexing because of its rarity and its pathologic similarities to other papillary or spindle cell neoplasms in the pediatric age group. We have studied eight cases of mesothelial or submesothelial-derived neoplasms of pleural (four cases) and peritoneal (four cases) origin in patients 4 to 17 years of age at diagnosis. Microscopically, six were epithelial, with papillary, tubuloglandular, and solid patterns. Two tumors were predominantly fibrous appearing, one a localized pleural fibroma and the other a diffuse pleural sarcomatoid mesothelioma. All of the tumors were immunoreactive for vimentin, and all except the pleural fibroma stained for either cytokeratin, epithelial membrane antigen, or both. None reacted with antibodies to carcinoembryonic antigen, placental alkaline phosphatase, or Leu-M1. At last follow-up, three patients were dead of tumor, three were alive and well, and two had been recently diagnosed and were undergoing treatment. These results indicate that the immunohistochemical profile delineated for mesothelioma in adults is equally applicable to mesothelial neoplasms in younger patients and is useful in establishing a diagnosis. The prognosis for malignant mesothelioma in childhood appears to be as unfavorable as the adult counterpart, with the possible exceptions of certain clinicopathologic subtypes.
A method for three-dimensional time-resolved optical tomography (2000)

We present an overview of time-resolved optical tomography together with the hardware and software methods that we have developed for a clinical instrument that implements this modality. The hardware is based on a multichannel photon-counting technique that records the histograms of photons time-of-flight through highly scattering and attenuating media. The software is based on a finite element model that is iteratively updated in order to minimize the difference between measured and modeled data. We have presented a first experimental reconstruction of a three-dimensional (3D) distribution of variable absorption and scattering coefficient, together with an ideal simulation of the same case. © 2000 John Wiley & Sons, Inc. Int J Imaging Syst Technol, 11, 2–11, 2000
On the Use of Cloud Computing for Scientific Workflows (2008)

This paper explores the use of cloud computing for scientific workflows, focusing on a widely used astronomy application-Montage. The approach is to evaluate from the point of view of a scientific workflow the tradeoffs between running in a local environment, if such is available, and running in a virtual environment via remote, wide-area network resource access. Our results show that for Montage, a workflow with short job runtimes, the virtual environment can provide good compute time performance but it can suffer from resource scheduling delays and widearea communications.
ADS-B and SSR data fusion and application (2012)

This paper analyzes the characteristic and limitation of ADS-B (Automatic Dependent Surveillance-Broadcast) and SSR (Secondary Surveillance Radar). A model and algorithm of the data fusion of ADS-B/SSR in civil aviation are proposed. The fusion model could provide a unique track for each aircraft with different avionics (with or without SSR transponder, or ADS-B avionics). As shown in the results verified by measured data, the use of ADS-B and SSR fusion can lead an important improvement in track accuracy, updating rate and an overall surveillance coverage from route to surface, while insuring the ATC surveillance system stable and reliable.
The Characteristics of TiC Coated on SKD11 by Chemical Vapor Deposition Process. (1992)

This paper deals with the characteristics of TiC coated on the tool steel of SKD11 by CVD method. The surface residual stress was measured by the X-ray stress measuring method. Also the characteristics of adhesion by the scratch test and wear resistance by the wear test were evaluated. Furthermore, the effect of heat treatment (quenched at 1020°Cand then at 450°C or 520°C) after CVD on these characteristics was considered. The results are as follows : (1) The residual stresses of TiC layer are compressive. However there is difference in values between after quenching and after tempering, and further there is also difference in values between in case of tempering at 450°C and tempering at 520°C. The stresses were -3.17GPa and -2.94GPa, respectively. These values were nearly equivalent to the calculated values of thermal stress. (2) Acoustic emission signal was detected corresponding with peeling off or damage of TiC layer. Also the critical load is subjected to the influence of substrate. The harder the substrate, the larger the critical load. (3) Wear resistance of SKD11 is extremely improved by means of coating CVD-TiC. When OHGOSHI type wear test is applied and TiC layer is very thin, not only the wear resistance of TiC layer but also the substrate of SKD11 is evaluated.
Navigation as a tool to visualize bone-covered hidden structures in transfrontal approaches (2004)

A retrospective analysis of 10 patients was performed to evaluate navigation systems in extranasal frontal skull base surgery. When performing a craniotomy following a bicoronal skin incision, the surgeon has to calculate the extent of the frontal sinus to avoid unnecessary damage to the dura or mucoceles later. Due to surgical morbidity including compression of the frontal lobe, many skull base surgeons have refused to use such an approach. Malformation or bone-destruction complicates the identification of the borders and increases the risk of side-effects. Navigation systems can be an alternative for calculating the frontal sinus outlines during surgery. In the authors' surgical procedure two different navigation systems were used. Conventional surgery using the transfrontal, transbasal or subcranial approach consisting of trepanation and craniotomy were performed, while the navigated surgical procedure was evaluated. The analysis showed that computer-assisted surgery (CAS) is applicable to extranasal frontal skull base surgery. In comparison to X-ray beam-controlled craniotomy, CAS is beneficial as it constitutes a noninvasive instrument of quality management. Furthermore, the analysis indicated that under the guidance of a navigation system a precise pre-surgical simulation is available in order to perform an optimal craniotomy and reconstruction of the frontal skull base.
Inhibition of striatal and retinal dopamine release via nociceptin/orphanin FQ receptors (2002)

1. We determined the effects of nociceptin/orphanin FQ and the NOP receptor ligands acetyl-Arg-Tyr-Tyr-Arg-Ile-Lys-NH(2) (Ac-RYYRIK-NH(2)) and naloxone benzoylhydrazone on transmitter release in vitro. 2. The electrically evoked tritium overflow from guinea-pig and mouse striatal slices and guinea-pig retinal discs preincubated with [(3)H]-dopamine was inhibited by nociceptin/orphanin FQ (pEC(50) 7.9, 7.6 and 8.6; E(max) 30, 50 and 55%). Ac-RYYRIK-NH(2) 0.032 microM and naloxone benzoylhydrazone 5 microM antagonized the effect of nociceptin/orphanin FQ in striatal slices of the guinea-pig (apparent pA(2) 9.1 and 6.8) and the mouse (apparent pA(2) 9.2 and 7.5) and strongly attenuated the effect of nociceptin/orphanin FQ 0.1 microM in guinea-pig retinal discs. Ac-RYYRIK-NH(2) 0.032 microM did not affect the evoked overflow by itself whereas naloxone benzoylhydrazone 5 microM inhibited it in each tissue. 3. The electrically evoked tritium overflow from mouse brain cortex slices preincubated with [(3)H]-noradrenaline was inhibited by nociceptin/orphanin FQ (pEC(50) 7.9, E(max) 85%), Ac-RYYRIK-NH(2) (pEC(50) 8.3, E(max) 47%) but not affected by naloxone benzoylhydrazone 5 microM. Ac-RYYRIK-NH(2) and naloxone benzoylhydrazone showed apparent pA(2) values of 8.6 and 6.9. 4. In conclusion, the inhibitory effect of nociceptin/orphanin FQ on dopamine release in the striatum and retina and on noradrenaline release in the cerebral cortex is mediated via NOP receptors. Ac-RYYRIK-NH(2) behaves as an extremely potent NOP receptor antagonist in the striatum and retina and as a partial agonist in the cortex.
Exploiting Psychoacoustic Properties to Achieve Transparent and Robust Audio Watermarking (2013)

This paper presents a novel scheme to adaptively determine the embedding strength for audio watermarking using quantization index modulation (QIM) in discrete wavelet packet transform (DWPT) domain. While the DWPT facilitates the signal analysis, the employment of a psychoacoustic model helps to not only acquire appropriate quantization steps for watermark embedding but also retrieve these steps back for watermark extraction. The effectiveness of this scheme has been proven using the perceptual evaluation of audio quality and bit error rates of the recovered watermark under common digital signal processing attacks. With the assistance of the psychoacoustic model, the combination of the DWPT and adaptive QIM attains satisfactory transparency and robustness with a payload as high as 183.03 bps.
LIFE CYCLE ASSESSMENT FOR THE PRODUCTION OF PALM BIODIESEL (2020)

A gate-to-gate life cycle assessment (LCA) for the production of palm biodiesel was performed. The LCA study was conducted using SimaPro software version 8.5, and the impact assessment was performed according to ReCiPe 2016 methodology. A three-year (2015)(2016)(2017) inventory data was obtained from five commercial palm biodiesel producers in Malaysia. Methanol, acids and sodium methoxide (catalyst) were identified as three major contributors to the environmental impacts. Impact assessment showed that replacement of fossilbased methanol with biomethanol produced from biogas is the most preferred option, saving up to 63% fossil resources and 22% reduction in global warming impact. Allocation based on economic value was found more suitable compared to mass or energy content. This is because both palm biodiesel and crude glycerol differ in terms of economic value and being used in different applications.
Atrial Fibrillation Initiated by Early Afterdepolarization-Mediated Triggered Activity during Acute Oxidative Stress: Efficacy of Late Sodium Current Blockade (2018)

Increased atrial tissue fibrosis combined with acute oxidative activation of CaMK II Initiate AF by EAD-mediated triggered activity. Specific block of the I<sub>Na-L</sub> with GS-967 effectively suppresses the AF. Drug therapy of oxidative AF in humans with traditional antiarrhythmic drugs remains suboptimal; suppressing I<sub>Na-L</sub> offers a potential new strategy for effective suppression of oxidative human AF that remains suboptimal.
An anti-HIV microbicide engineered in commensal bacteria: secretion of HIV-1 fusion inhibitors by lactobacilli (2006)

The development of recombinant lactobacilli expressing HIV-1 fusion inhibitors with potent neutralizing activity represents an important step toward the development of a live microbial (topical) microbicide against HIV-1 transmission.
ChemInform Abstract: KONJUGIERTE HALOGENIERUNG UNGESAETTIGTER VERBINDUNGEN 3. MITT. SYNTH. AUF DER GRUNDLAGE VON PRODUKTEN EINER KONJUGIERTEN HALOGENIERUNG (1971)

Abstract Durch Behandlung mit KOH‐Wasser bei 140‐160°C lassen sich die Propanole (I) in die Oxetane (II) (Ausbeute 14 bzw. 52%) überführen; neben dem Oxetan (IIa) entstehen dabei 2‐Fluor‐ und 3‐Chlor‐propen‐(2)‐ol‐(1) (6 bzw. 5%).
A survey of hybrid metaheuristics to minimize makespan of job shop scheduling problem (2017)

To develop effective, efficient scheduling methods is an important interdisciplinary challenge for any enterprise to sustain in a competitive position of fast changing markets. The goal of scheduling is to optimize different criteria of a facility such as makespan, mean flow time, resource idle time, total tardiness, number of tardy jobs/projects, in-process inventory cost, cost of being late etc. As problem size increases, performance decreases and finding optimal solution to this problem within reasonable time under some constraints turns this problem NP-Hard. Brute force algorithm normally fails to find optimum solution for large problem size and hence approximate solutions are proposed for near optimal value for given objective criterion. This paper presents a brief survey on hybrid metaheuristics for solving job shop problem for minimizing the makespan.
Research letterLignocellulose degradation during the life cycle of Agaricus bisporus (1983)

Lignocellulose degradation was monitored during the complete life cycle of the edible mushroom Agaricus bisporus grown on composted straw. Lignin and cellulose degradation were assayed by the use of 14C-labelled lignin and cellulose. Agaricus degraded both polymers but cellulose degradation was more extensive. Cellulolysis increased markedly at fruit body production and was greater still in non-axenically fruited cultures. No large change in the rate of lignin degradation occurred during the life cycle.
Nanoscale Positional Recognition of Multiple Probes of a Multiple-Scanning-Probe Microscope (2007)

Multiple-scanning-probe microscopes (MPSPMs) are one of the powerful tools which can measure physical properties of nanostructures and nanodevices. However, it is, in general, difficult to operate multiple probes in a nanoscale region and to measure probe-to-probe distance before the actual property measurements. To solve such difficulty, we have developed a control system specialized for multiple-scanning-probe measurements and used the system with our home-made MPSPM operated in air. In this paper, we report that how to realize safe and easy recognition for nanoscale positional relationship between four probes by applying sample scanning method. we show, for the first time, simultaneously acquired four STM images using four independently-controlled probes. All of the four images involve the identical area on the sample surface, indicating that the four probes have scanned over the same area. Using the four STM images, we have calculated the shift vectors which describe nanoscale positional relationships between the four STM images, in other words, between four probe-to-sample contact points. This is an important achievement towards further applications of MPSPM measurements in nanotechnology.
Pulse propagation in Bragg‐resonant multiple quantum wells: from pulse breakup to compression (2003)

The nonlinear propagation of subpicosecond pulses resonant to the hh 1s exciton in Bragg-periodic multiple quantum wells is investigated experimentally and theoretically. We show coherent pulse breakup and its suppression for increasing pulse intensity in good agreement with calculations based on the semiconductor Maxwell-Bloch equations. For highly nonlinear excitation, pulse compression is observed which is strongly enhanced by the additional contribution of self-phase modulation in the barrier and substrate material.
Pyrometric temperature controller for million degree per second heating (1990)

A high-power proportional temperature controller, using a fast infrared pyrometer, has been developed to change and control the temperature of metallic ribbon samples with microsecond response. The apparatus provides uniform and controlled heating for time-resolved x-ray scattering studies of structural phase transitions. When high-power pulse heating is used, the system is capable of increasing the sample temperature at rates in excess of 106 K/s, without overshoot and with subsequent control to ±1 K at temperatures as low as 650 K.
Structural Determinants of Pip2 Regulation of Inward Rectifier KATP Channels (2000)

Phosphatidylinositol 4,5-bisphosphate (PIP(2)) activates K(ATP) and other inward rectifier (Kir) channels. To determine residues important for PIP(2) regulation, we have systematically mutated each positive charge in the COOH terminus of Kir6.2 to alanine. The effects of these mutations on channel function were examined using (86)Rb efflux assays on intact cells and inside-out patch-clamp methods. Both methods identify essentially the same basic residues in two narrow regions (176-222 and 301-314) in the COOH terminus that are important for the maintenance of channel function and interaction with PIP(2). Only one residue (R201A) simultaneously affected ATP and PIP(2) sensitivity, which is consistent with the notion that these ligands, while functionally competitive, are unlikely to bind to identical sites. Strikingly, none of 13 basic residues in the terminal portion (residues 315-390) of the COOH terminus affected channel function when neutralized. The data help to define the structural requirements for PIP(2) sensitivity of K(ATP) channels. Moreover, the regions and residues defined in this study parallel those uncovered in recent studies of PIP(2) sensitivity in other inward rectifier channels, indicating a common structural basis for PIP(2) regulation.
Reductive Coupling of Aldimines to Vicinal Diamines Using Zn Powder in Aqueous Basic Media (1998)

Reductive coupling of aldimines into vicinal diamines has been performed by the action of zinc powder and 10% sodium hydroxide solution without using any organic solvents at ambient temperature in high yields.
Carbonate Fuel Cell Power Plant Systems (1981)

Carbonate fuel cells are an attractive means of developing highly efficient power plants capable of achieving low atmospheric emissions. Because carbonate fuel cells can be used with coal derived fuel gases and their operating temperatures allow the use of turbomachinery bottoming cycles, they are well suited for large installations like central utility stations. Presently, system development activity is directed toward evaluating the readiness of gasifier and fuel processor technology, defining candidate cycle configurations, and calculating projected plant efficiencies.
ChemInform Abstract: Improved Methods for the Synthesis of Aza‐Crown Macrocycles and Cryptands (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A split pre-conditioned conjugate gradient method for massive MIMO detection (2017)

In massive multiple-input multiple-output (MIMO) mobile system, the computational complexity of signal detection increases exponentially along with the growing number of antennas. For example, the sub-optimal linear detection schemes, such as zero forcing (ZF) detector and minimum mean square error (MMSE) detector, always have to balance the performance and complexity resulted from the large-scale matrix inversion operations. Recently, some iterative linear solvers, such as conjugate gradient (CG), have been proposed to address this issue. These series of detection algorithms offer a better tradeoff between error-rate performance and computational complexity by avoiding the computation-hungry operations like matrix inversion. However, when the the system loading factor ρ goes up, their results are no longer satisfactory. To solve the aforementioned issues, this paper 1) first introduces a novel, low-complexity pre-conditioner by exploring the properties of the equalization matrix and 2) then proposes a split pre-conditioned conjugate gradient (SPCG) method to speed up the convergence rate of detection. Both analytical and numerical results have demonstrated the performance and complexity advantages of the proposed algorithm over the sate-of-the-art ones. The proposed detector outperforms the conventional CG detector with around 2 dB for BER = 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">−4</sup> . When the number of user antennas is relatively large, its complexity is only 25% of the existing pre-conditioned conjugate gradient detector based on incomplete Cholesky decomposition (ICCG).
Restrictive Transfusion Practice in Adults Receiving Venovenous Extracorporeal Membrane Oxygenation: A Single-Center Experience (2020)

These results suggest that the adoption of a more restrictive approach to RBC transfusion during venovenous extracorporeal membrane oxygenation is more cost-effective and associated with similar survival outcomes, than when compared with a more liberal approach.
Predilution Versus Postdilution During Continuous Venovenous Hemofiltration: A Comparison of Circuit Thrombogenesis (2006)

During continuous venovenous hemofiltration, predilution can prolong circuit survival time, but the underlying mechanism has not been elucidated. The aim of the present study was to compare predilution with postdilution, with respect to circuit thrombogenesis. Eight critically ill patients were treated with both predilutional and postdilutional continuous venovenous hemofiltration in a crossover fashion. A filtration flow of 60 ml/min was used in both modes. We chose blood flows of 140 and 200 ml/min during predilution and postdilution, respectively, to keep the total flow through the hemofilter constant. Extracorporeal circuit pressures were measured hourly, and samples of blood and ultrafiltrate were collected at five different time points. Thrombin-antithrombin complexes and prothrombin fragments F1 + 2 were measured by ELISA, and platelet activation was assessed by flow cytometry. No signs of thrombin generation or platelet activation were found during either mode. During postdilution, baseline platelet count and maximal prefilter pressure had a linear relation, whereas both parameters were inversely related with circuit survival time. In summary, predilution and postdilution did not differ with respect to extracorporeal circuit thrombogenesis. During postdilution, baseline platelet count and maximal prefilter pressure were inversely related with circuit survival time.
Mass Spectrometry of Some Substituted 2-Benzylidenecyclohexanone Oximes (1973)

The mass spectra of several substituted 2-benzylidenecyclohexanone oximes have been determined at 70 eV and at lower ionization voltages. The major fragmentation pathways for the oximes are loss of the ortho substituent from the parent ion as well as loss of hydroxyl radical. The facility of loss of the ortho substituent is compared with a similar process involved in the fragmentation of substituted 2-benzylidenecyclohexanones. In addition, the mass spectrum of the acetate of 2-benzylidenecyclohexanone oxime was determined and showed a M – 1 peak and also a peak corresponding to the parent oxime formed by loss of ketene.