gebhart/patrepeval huggingface dataset:
Free atomic consistency in storage class memory with software based write-aside persistence (2015)

This paper describes a lightweight software library to solve the challenges [5, 3, 1, 4, 2] of programming storage class memory (SCM). It provides primitives to demarcate failure-atomic code regions. SCM loads and stores within each de-marcated code region (called a "wrap") are routed through the library, which buffers updates and transmits them to SCM locations asynchronously while allowing their speedy propagation from writers to readers through CPU caches.
Service-based Architecture with Product-centric Control in a Production Island-based Agile Factory (2019)

This paper presents the Aalto Factory of the Future, an ongoing initiative in establishing an agile, net-centric production-island based factory utilizing service oriented architecture concepts. Recent progress towards realizing the software architecture with product-centric control in the facility is reported in this paper, which features communication between different production islands, and actors in the space between the production islands and humans.
Utility-Based Resource Allocation for Layer-Encoded Multimedia Multicasting over Wireless Relay Networks (2009)

Layer-encoded multimedia multicasting (LMM) has emerged in recent years to support heterogeneous subscriber stations with diverse computing and networking capabilities. With the advance of broadband wireless access technologies, wireless relay networks (WRNs) are expected to provide significant improvement on throughput and extension of coverage for next-generation wireless systems. In this paper, we study a radio resource allocation problem with the consideration of wireless interferences for LMM over WRNs. The problem is formally formulated, and the objective of the problem is to maximize the system utility where the utility is defined as user satisfaction. The NP-hardness of the problem is demonstrated, and then a heuristic algorithm is proposed. A series of experiments are conducted to demonstrate the capability of our proposed algorithm.
Direct Interaction of the N-terminal Domain of Focal Adhesion Kinase with the N-terminal Transactivation Domain of p53 (2005)

Focal adhesion kinase (FAK) is a nonreceptor kinase that is overexpressed in many types of tumors and associates with multiple cell surface receptors and intracellular signaling proteins through which it can play an important role in survival signaling. A link between FAK and p53 in survival signaling has been reported, although the molecular basis of these events has not been described. In the present study, we report that FAK physically and specifically interacts with p53 as demonstrated by pull-down, immunoprecipitation, and co-localization analyses. Using different constructs of N-terminal, central, and C-terminal fragments of FAK and p53 proteins, we determined that the N-terminal fragment of FAK directly interacts with the N-terminal transactivation domain of p53. Inhibition of p53 with small interfering p53 RNA resulted in a decreased complex of FAK and p53 proteins in 293 cells, and induction of p53 with doxorubicin in normal human fibroblasts caused an increase of FAK and p53 interaction. Introduction of the FAK plasmid into p53-null SAOS-2 cells was able to rescue these cells from apoptosis induced by expression of wild type p53. In HCT 116 colon cancer cells, co-transfection of FAK plasmid with p21, MDM-2, and BAX luciferase plasmids resulted in significant inhibition of p53-responsive luciferase activities, demonstrating that FAK can reduce transcriptional activity of p53. The results of the FAK and p53 interaction study strongly support the conclusion that FAK can suppress p53-mediated apoptosis and inhibit transcriptional activity of p53. This provides a novel mechanism for FAK-p53-mediated survival/apoptotic signaling.
History of the World Federation of Societies for Laser Medicine and Surgery (WFSLMS) and its Non-Profit Organization (NPO-WFSLMS)Part 1: Origins to Inaugural Meeting, 2005 (2014)

Both the WFSLMS and NPO-WFSLMS were therefore on their way to working together for a cohesive approach to try and coordinate the work of all societies dedicated to laser medicine and surgery under the WFSLMS umbrella, with NPO-WFSLMS continuously gathering, administering and disbursing the funds to allow the WFSLMS to run its 4-yearly meetings.
Lymphoid Cell Dependent (K‐Cell) Lysis of Human Erythrocytes Sensitized with Rhesus Alloantibodies (1976)

An in vitro homologous system using human Rhesus alloantibodies and target erythrocytes labelled with 51Cr has been used to demonstrate the ability of normal peripheral blood lymphoid cells to lyse antibody-coated human red cells. The results obtained suggest that this type of mechanism may be relevant to certain haemolytic diseases in man.
Evaluation of energy storage method using liquid air (2000)

An energy storage system using liquid air for high storage efficiency is studied. Liquid air is produced by off-peak power and can be stored at atmospheric pressure in a large tank. When on-peak power is needed, the stored liquid air is pumped to high pressure and fed to the combustor of a gas turbine. Then, power generation is more than doubled from that of a system with an ordinary air compressor. Furthermore, energy storage efficiency of this system is significantly increased above that of a pumping-up power plant when low-temperature liquid air is used to produce new liquid air. © 2000 Scripta Technica, Heat Trans Asian Res, 29(5): 347–357, 2000
Inhibition by Interferon of Polyoma Virus-induced Cell DNA Synthesis in Mouse Peritoneal Macrophages (1973)

SUMMARY Mouse peritoneal macrophages from C57 Bl and NIH mice were examined after infection with polyoma virus. Cell DNA synthesis was stimulated in both cell types to the same extent between two and three days after addition of virus. Morphological changes appearing soon after infection were reversed by the second or third day. The cells did not acquire other properties associated with the transformed state. Treatment with mouse interferon up to 48 h after infection inhibited the virus-induced host DNA synthesis while morphological changes were not affected.
Managing a complication after direct stenting: removal of a maldeployed stent with rotational atherectomy (2005)

A 40 year old patient presented with acute anterior wall infarction. A non-calcified lesion was stented directly without significant expansion of the stent. Rotational atherectomy successfully removed parts of the maldeployed stent and resistant arterial wall substance allowing full dilatation of the lesion.
Ara12 subtilisin-like protease from Arabidopsis thaliana: purification, substrate specificity and tissue localization (2003)

A C-terminal portion of Ara12 subtilisin-like protease (residues 542-757) was expressed in Escherichia coli cells as a fusion protein bound to maltose binding protein. Polyclonal antisera raised against the expressed protein were used to examine the tissue specificity and subcellular localization of Ara12. The protease was found predominantly in the silique and stem of plants, but was hardly detectable in leaf and not seen in root tissue. The distribution observed using immunological techniques is different from that seen by an RNA analysis study, which demonstrated similar mRNA abundance in the stem and leaves. Using immunogold labelling, Ara12 was shown to have an extracellular localization and was found in the intercellular spaces in stem tissue. Ara12 protease was purified to homogeneity from Arabidopsis thaliana cell suspension cultures by anion exchange and hydrophobic interaction chromatography. Proteolytic activity of Ara12 was inhibited by a number of serine protease inhibitors, but was almost unaffected by inhibitors of other catalytic classes of proteases. Optimal proteolytic activity was displayed under acidic conditions (pH 5.0). Ara12 activity was relatively thermostable and was stimulated in the presence of Ca2+ ions. Substrate specificity studies were conducted using a series of internally quenched fluorogenic peptide substrates. At the P1 position of substrates, hydrophobic residues, such as Phe and Ala, were preferred to Arg, whilst at the P1' position, Asp, Leu and Ala were most favoured. Possible functions of Ara12 are discussed in the light of the involvement of a number of plant subtilisin-like proteases in morphogenesis.
Bayesian neural networks for the prediction of stochastic travel times in urban networks (2011)

Urban travel time prediction has received much less attention than predictions on freeways, perhaps because urban travel times show much larger variations and are therefore much harder to predict. However, urban travel time can form a substantial part of the total travel time of a road user and therefore effort should be taken to predict urban travel times. In this study, neural networks are used for urban travel time prediction because these have shown to be able to deal with noisy data. Bayesian techniques are used for training of the networks, resulting in committees with lower error and in confidence bounds. It is shown that the neural network committees are capable of predicting the ‘low-frequency trend’, which can be seen when the high-frequency component of travel time is removed using de-noising. The errors of the predictions on the low-frequency trend are in the same order as when predicting freeway travel times, and it is shown that the predicted confidence bounds are accurate.
Rugged Single Domain Antibody Detection Elements for Bacillus anthracis Spores and Vegetative Cells (2012)

Significant efforts to develop both laboratory and field-based detection assays for an array of potential biological threats started well before the anthrax attacks of 2001 and have continued with renewed urgency following. While numerous assays and methods have been explored that are suitable for laboratory utilization, detection in the field is often complicated by requirements for functionality in austere environments, where limited cold-chain facilities exist. In an effort to overcome these assay limitations for Bacillus anthracis, one of the most recognizable threats, a series of single domain antibodies (sdAbs) were isolated from a phage display library prepared from immunized llamas. Characterization of target specificity, affinity, and thermal stability was conducted for six sdAb families isolated from rounds of selection against the bacterial spore. The protein target for all six sdAb families was determined to be the S-layer protein EA1, which is present in both vegetative cells and bacterial spores. All of the sdAbs examined exhibited a high degree of specificity for the target bacterium and its spore, with affinities in the nanomolar range, and the ability to refold into functional antigen-binding molecules following several rounds of thermal denaturation and refolding. This research demonstrates the capabilities of these sdAbs and their potential for integration into current and developing assays and biosensors.
Dynamic reaction on the Maruti hard real-time operating system (1994)

The search-based techniques of classical AI Planning systems are ill-suited to the demands of highly dynamic and complex environments. As a result, research has turned towards stimulusdriven &amp;quot;reactive&amp;quot; systems in an effort to develop intelligent control systems that can operate in rapidly changing and unpredictable environments. An important class of control systems, known as &amp;quot;mission-critical&amp;quot; real-time systems, is further complicated by the potential for catastrophic failure if the system does not produce acceptable behavior within strict deadlines. This makes it imperative that system operation can be proven correct before deployment. In this paper, we discuss the Dynamic Reaction (DR) model of reactive system design, and its use on the Maruti hard real-time operating system. Together, DR and Maruti provide the basis for demonstrable properties of behavioral correctness and timeliness in mission-critical environments. We show how the DR/Maruti combination allows us to develop contro...
Efficient hydrogen storage in defective graphene and its mechanical stability: A combined density functional theory and molecular dynamics simulation study (2020)

A combined density functional theory and molecular dynamics approach is employed to study modifications of graphene at atomistic level for better H2 storage. The study reveals H2 desorption from hydrogenated defective graphene structure, V222, to be exothermic. H2 adsorption and desorption processes are found to be more reversible for V222 as compared to pristine graphene. Our study shows that V222 undergoes brittle fracture under tensile loading similar to the case of pristine graphene. The tensile strength of V222 shows slight reduction with respect to their pristine counterpart, which is attributed to the transition of sp2 to sp3-like hybridization. The study also shows that the V222 structure is mechanically more stable than the defective graphene structure without chemically adsorbed hydrogen atoms. The current fundamental study, thus, reveals the efficient recovery mechanism of adsorbed hydrogen from V222 and paves the way for the engineering of structural defects in graphene for H2 storage.
IC‐P‐107: SUVN‐90716: A Selective 5‐HT6 Antagonist for the Potential Treatment of Alzheimer's Disease (2010)

Alzheimer's disease (AD) is a chronic and progressive neurodegenerative disorder, which is characterized by a decline in cognition and memory formation. AD is a leading cause of socioeconomic healthcare burden in developed world. 5-HT6 receptors are reported to be involved in cognition and memory formation as well as its retention. Above information coupled with a number of molecules in clinical development implicate the potential use of 5-HT6 receptor antagonists to treat conditions like Alzheimer's disease. A cell based functional assay utilizing a recombinant cell line was used to screen and evaluate novel compounds. Pharmacokinetic studies were conducted in rats and Beagle dog and brain penetration studies were conducted in rats. SUVN-90716 was evaluated for its procognitive property in the novel object recognition task and Morris water maze task in rats. In vivo brain microdialysis experiments were carried out to determine the effect of this 5-HT6 receptor antagonist on acetylcholine levels in medial prefrontal cortex of conscious rats. SUVN-90716 was identified as a potent 5-HT6 receptor antagonist with excellent selectivity over other targets evaluated. The compound had a good oral bioavailability in rats (29%) and dogs (92%) with adequate brain penetration in rats. The compound reversed the time induced memory deficit in the novel object recognition task. SUVN-90716 also reversed the scopolamine induced memory deficit in the Morris water maze task as well as the novel object recognition task. Acute administration of SUVN-90716 (3 and 10 mg/kg, s.c.) increased extracellular acetylcholine levels in the medial prefrontal cortex in a dose-dependent manner. SUVN-90716 is a potent, selective, orally bioavailable 5-HT6 antagonist with adequate brain penetration and showing procognitive properties in animal models of cognition. Overall profile of the compound demonstrates its utility in the treatment of cognitive impairment associated with AD and other psychiatric disorders.
Risk factors for infantile hypothermia in early neonatal life (1990)

Hypothermia in infancy is not uncommon among the low socioeconomic population in various parts of the world. It is prevalent in Israel and is associated with severe morbidity and mortality. We tried to identify neonates at risk among the population of the Negev district of Israel. Ninety-one infant hospitalized with infantile hypothermia (IH) during the years 1974 to 1981 were identified. The neonates belonged to two distinct ethnic groups, Bedouins and Jews, and were compared with 120 healthy controls of similar background. Our data show that premature infants and babies with low birth weight born during the cold season to young (inexperienced) mothers of lower socioeconomic strata and who sustained perinatal morbidity are at risk for IH. It is suggested that parents of infants at risk should be approached while the baby is till in the nursery, be advised about the possibility of hypothermia, and institute the appropriate preventive measures.
Orthogonal manipulations of phase and phase dispersion in realization of azimuthal angle-resolved focusings (2021)

In conventional achromatic metasurfaces configurations where the engineering paths of phase and phase dispersion are the same, limited phase dispersion control range inevitably imposes a restriction on the broadband device size, which otherwise can be arranged in a periodic manner to achieve infinite size at a single wavelength. In addition to this, the adoption of geometric-phase structures imparts the orthogonal circular polarization conversion, whereas the birefringent propagation-phase structures bring an uncertain polarization state, thus resulting in an incomplete polarization conversion. In this study, we propose an azimuthal angle-resolved beam-deflection metasurface at the same polar angle with orthogonal phase and phase dispersion control paths. Periodic expansion is implemented to achieve unlimited device size along the phase control path and the broadband light is monotonously and azimuthally deflected to the designated polar angle with the delicate design along the dispersion path. In addition, the non-crossed polarized light arising from the incomplete geometric phase control would naturally separate from the cross-polarized light when adjusting the planar geometric parameters of the birefringent metaatoms to realize dispersion control. This design scenario may find applications in phased-array detection applications where beams are azimuthally swept to search targets at one polar angle.
Luminescent Ruthenium Polypyridyl Complexes Containing Pendant Pyridinium Acceptors (1996)

Direct attachment of putative electron acceptors ((bi)pyridinium ions) to either Ru(bpy)32+ or Ru(1,10-phenanthroline)32+ (excellent photo-excited-state electron donors) leads to enhancement of excited-state lifetimes, rather than the diminution anticipated from electron transfer quenching. An evaluation of photo redox and emission energetics suggests that charged “quencher” attachment lengthens luminescence lifetimes by (a) diminishing the reductant strength of the photo excited state, (b) inhibiting intersystem crossing to a short-lived d−d state, and/or (c) diminishing Franck−Condon factors for nonradiative decay.
Ammonia Molecular Beam Epitaxy ofIII‐Nitrides (2019)

The advances in III-nitride semiconductor technologies over the past two decades have stimulated progress in a variety of nitride epitaxial techniques. Molecular beam epitaxy (MBE) of III-nitrides requires the use of a gaseous precursor to provide the nitrogen anion. When diatomic nitrogen gas is used, plasma cracking of the triple bond is necessary to liberate atomic nitrogen, termed plasma-assisted MBE (PAMBE). This chapter presents a complementary technique known as ammonia MBE (NH3-MBE). The use of ammonia gas as the precursor removes the plasma cracking requirement, as ammonia will decompose at the growth surface for most growth temperatures. NH3-MBE growth and materials characterization have been undertaken by several research groups. This chapter presents a brief overview of the growth space, materials results, and potential applications of the NH3-MBE technique.
PRONTO: Preamble Overhead Reduction With Neural Networks for Coarse Synchronization (2023)

In IEEE 802.11 WiFi-based waveforms, the receiver performs coarse time and frequency synchronization using the first field of the preamble known as the legacy short training field (L-STF). The L-STF occupies upto 40% of the preamble length and takes upto <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$32 \mu \text{s}$ </tex-math></inline-formula> of airtime. With the goal of reducing communication overhead, we propose a modified waveform, where the preamble length is reduced by eliminating the L-STF. To decode this modified waveform, we propose a neural network (NN)-based scheme called PRONTO that performs coarse time and frequency estimations using other preamble fields, specifically the legacy long training field (L-LTF). Our contributions are threefold: (i) We present PRONTO featuring customized convolutional neural networks (CNNs) for packet detection and coarse carrier frequency offset (CFO) estimation, along with data augmentation steps for robust training. (ii) We propose a generalized decision flow that makes PRONTO compatible with legacy waveforms that include the standard L-STF. (iii) We validate the outcomes on an over-the-air WiFi dataset from a testbed of software defined radios (SDRs). Our evaluations show that PRONTO can perform packet detection with 100% accuracy, and coarse CFO estimation with errors as small as 3%. We demonstrate that PRONTO provides upto 40% preamble length reduction with no bit error rate (BER) degradation. We further show that PRONTO is able to achieve the same performance in new environments without the need to re-train the CNNs. Finally, we experimentally show the speedup achieved by PRONTO through GPU parallelization over the corresponding CPU-only implementations.
Time domain Green's function for an infinite phased periodic line array of dipoles (2002)

Periodic arrays of radiating or scattering elements play an important role in phased array antennas, frequency selective surfaces and related applications. We have begun a systematic investigation of the time domain (TD) behavior of Green's functions which are relevant for the characterization of truncated planar periodic arrays, with emphasis on the TD Floquet waves (FW) in the propagating and evanescent parameter regimes. Such waves on semi-infinite and finite square arrays of dipoles have been and are being investigated in the frequency domain (FD). These prototypes furnish the models for the present studies in the time domain. Our principal aim is to understand the TD wave physics and phenomenologies on simple prototypes, invoking various methods that synthesize the solution from different perspectives. This paper deals with the first prototype, an infinite linearly phased periodic array of axial dipole radiators arranged along the z-axis of a rectangular or cylindrical coordinate system. This prototype is a basic building block for line arrays formed by a finite number of transversely phased line sources, and it also plays a direct role in the modeling of diffraction effects due to the transverse truncations. The prototype line array of dipoles is simple enough to admit closed form exact solutions which can be obtained via alternative routes. A route which includes inversion from the FD via the conventional Fourier transform is presented.