gebhart/patrepeval huggingface dataset:
Scheduling Prioritized Services in Multihop OFDMA Networks (2010)

Growing popularity of high-speed wireless broadband access for real-time applications makes it increasingly relevant to study the admission control and scheduling of flows in a service differentiated manner. Next-generation wireless broadband networks employ orthogonal frequency division multiple access (OFDMA) technology that enables multiple users to communicate at the same time using a time-frequency grid. In this paper, we provide a mathematical model for prioritized admission control and scheduling in OFDMA-based multihop wireless networks. The problem is formulated as an integer linear program (ILP) that does joint admission control and scheduling of flows while satisfying its rate and latency requirements. We propose different heuristic algorithms for scheduling priority-based flows in centralized multihop OFDMA networks. We define the “Flow Admittance” (FA) metric and compare the different scheduling schemes based on this metric. Simulation results show that the Start from Frame Beginning (SFB) heuristic performs well in most of the scenarios. We also propose a combination approach that merges multiple heuristics. The FA values obtained from the combination approach are close to the ILP while incurring computation time orders of lower magnitude.
Synthesis and properties of DNA oligomers containing 2′-deoxycytidine-N-oxide (2006)

The main product obtained by oxidation of 2'-deoxycytidine with hydrogen peroxide is 2'-deoxycytidine N-oxide. Although its chemical synthesis and properties of 2'-deoxycytidine N-oxide have been well established, little has been reported about the chemical and biochemical behavior of DNA oligomers containing this modified deoxynucleoside. In this study, we synthesized DNA oligomers containing 2'-deoxycytidine N-oxide by use of a post-synthetic oxidative method. It should be noted that this modified base could be incorporated in oligodeoxynucleotides at appropriate positions by this strategy. The ability of the base pair formation was significantly low because of the blocking of the canonical hydrogen bonding site.
Intercomparison of aerosol-cloud-precipitation interactions in stratiform orographic mixed-phase clouds (2010)

Abstract. Anthropogenic aerosols serve as a source of both cloud condensation nuclei (CCN) and ice nuclei (IN) and affect microphysical properties of clouds. Increasing aerosol number concentrations is hypothesized to retard the cloud droplet collision/coalescence and the riming in mixed-phase clouds, thereby decreasing orographic precipitation. This study presents results from a model intercomparison of 2-D simulations of aerosol-cloud-precipitation interactions in stratiform orographic mixed-phase clouds. The sensitivity of orographic precipitation to changes in the aerosol number concentrations is analyzed and compared for various dynamical and thermodynamical situations. Furthermore, the sensitivities of microphysical processes such as collision/coalescence, aggregation and riming to changes in the aerosol number concentrations are evaluated and compared. The participating models are the Consortium for Small-Scale Modeling's (COSMO) model with bulk-microphysics, the Weather Research and Forecasting (WRF) model with bin-microphysics and the University of Wisconsin modeling system (UWNMS) with a spectral ice-habit prediction microphysics scheme. All models are operated on a cloud-resolving scale with 2 km horizontal grid spacing. The results of the model intercomparison suggest that the sensitivity of orographic precipitation to aerosol modifications varies greatly from case to case and from model to model. Neither a precipitation decrease nor a precipitation increase is found robustly in all simulations. Qualitative robust results can only be found for a subset of the simulations but even then quantitative agreement is scarce. Estimates of the second indirect aerosol effect on orographic precipitation are found to range from –19% to 0% depending on the simulated case and the model. Similarly, riming is shown to decrease in some cases and models whereas it increases in others which implies that a decrease in riming with increasing aerosol load is not a robust result. Furthermore, it is found that neither a decrease in cloud droplet coalescence nor a decrease in riming necessarily implies a decrease in precipitation due to compensation effects by other microphysical pathways. The simulations suggest that mixed-phase conditions play an important role in reducing the overall susceptibility of clouds and precipitation with respect to changes in the aerosols number concentrations. As a consequence the indirect aerosol effect on precipitation is suggested to be less pronounced or even inverted in regions with high terrain (e.g., the Alps or Rocky Mountains) or in regions where mixed-phase microphysics climatologically plays an important role for orographic precipitation.
Spectroelectrochemical study of the reductive desorption and the oxidative redeposition of a monolayer of 1-hexadecanethiols chemisorbed on gold(111). (2000)

We present a spectroelectrochemical study of the reductive desorption and the oxidative redeposition of a monolayer of 1-hexadecanethiols on Au(111) in an aqueous alkaline electrolyte solution. The solvent/thiol interactions were found to play an important role in the electrodeposition of self-assembled monolayers of low-solubility thiols. The orientation of the alkane chains in a monolayer remains unchanged after its reductive desorption and oxidative redeposition. The reductive desorption/oxidative redeposition of low-solubility thiols on Au(111) proceed through a two step mechanism. The first step of the reductive desorption is ascribed to the reduction of chemisorbed thiols. The second step of the reductive desorption occurs at a more negative potential and is assigned to the reorientation of the monolayer of physisorbed thiolates into micelles. The unblocking of the Au(111) surface caused by this reorientation of the thiolates allows the formation of an electrical double layer. (Abstract shortened by UMI.)
Causal relationships affect perceived audio-visual synchrony : reversed effects for different judgment methods (2007)

Subjective synchrony in audio-visual timing perception is typically characterized by the point of subjective equality (PSE). It can be estimated from the 50% point in temporal order judgments (TOJ), or from the center of the synchronous response curve in a synchrony judgement (SJ) procedure. Using both TOJ and SJ procedures, we estimated PSEs for Newton's Cradle, showing a left-to-right pendulum movement. Three visual conditions were used: (1) the entire stimulus, (2) the left, or (3) the right half. In conditions 1 and 2, the visual movement appears to cause the collision, whereas in condition 3 the visual movement appears to result from the collision. Using an SJ procedure, conditions 1 and 2 yielded positive PSEs (i.e. audio delayed relative to video), whereas for condition 3 perceptual synchrony coincided with physical synchrony. Using a TOJ response rule resulted in slightly negative PSEs for conditions 1 and 2, whereas condition 3 yielded highly positive PSEs. Not only do these data show opposite effects for the two response rules, but they indicate strategic variation in the TOJ task. That is, the TOJ PSEs consistently shifted towards the side of the synchrony curve with the steeper slope, indicating the region of greater observer sensitivity.
No significant influence of HLA determinants on susceptibility to hepatitis C virus infection in Caucasian patients with end‐stage renal disease (1996)

In hepatitis C, both susceptibility to infection and the course of disease may depend on differences in the immune response. As the major histocompatibility complex (MHC) plays a crucial role in antigen presentation, we investigated a possible relationship between susceptibility to hepatitis C virus (HCV) infection and human leucocyte antigen (HLA) alleles. Therefore, phenotype frequencies of HLA were compared in 186 anti-HCV positive patients with end-stage renal disease (ESRD) to 328 anti-HCV negative patients with ESRD. HLA class I alleles were determined serologically and HLA class II alleles (DRB1, DQA1, DQB1) by the polymerase chain reaction sequence-specific oligonucleotide (PCR-SSO) technique. Additionally, in anti-HCV positive patients we looked for a relationship between the activity of hepatitis C (indicated by elevation of transaminases or the presence of viremia) and HLA determinants. For the three criteria (antibody status, elevation of transaminases and viremia) a significant association to HLA alleles was not found in patients with ESRD. This suggests that neither susceptibility to HCV infection nor the biochemical activity of hepatitis and HCV-RNA positivity seem to be strongly related to HLA status in Caucasian patients with end-stage renal disease.
User variance and its impact on video retrieval benchmarking (2009)

In this paper, we describe one of the largest multi-site interactive video retrieval experiments conducted in a laboratory setting. Interactive video retrieval performance is difficult to cross-compare as variables exist across users, interfaces and the underlying retrieval engine. Conducted within the framework of TRECVID 2008, we completed a multi-site, multi-interface experiment. Three institutes participated involving 36 users, 12 each from Dublin City University (DCU, Ireland), University of Glasgow (GU, Scotland) and Centrum Wiskunde & Informatica (CWI, the Netherlands). Three user interfaces were developed which all used the same search service. Using a latin squares arrangement, each user completed 12 topics, leading to 6 TRECVID runs per site, 18 in total. This allowed us to isolate the factors of users and interfaces from retrieval performance. In this paper we present an analysis of both the quantitative and qualitative data generated from this experiment, demonstrating that for interactive video retrieval with "novice" users, performance can vary by up to 300% for the same system using different sets of users, whilst differences in performance of interface variants was in comparison not statistically different. Our results have implications for the manner in which interactive video retrieval experiments using non-expert users are evaluated. The primary focus of this paper is in highlighting that non-expert users generate very large performance fluctuations, which may either mask or create system variability. The discussion of why this happened is not covered by this paper.
Optical buffering scheme based on two-ring resonator system (2008)

We propose a scheme based on two-ring resonator system that can realize flat delay and transmission response with delay-bandwidth product (DBP) higher that those achieved in previously proposed schemes. The spectrum flatness and DBP are two key parameters that characterize the maximum number of bits that can be buffered without distortion for certain signal operating bandwidth. Simple time domain simulation shows that our scheme can achieve the same buffering time with 2 to 4 times smaller number of modules, which indicates DBP of 2 to 4 times larger than those of side-coupled ring structure and coupled resonator optical.
Discovery of Imidazopyridine Derivatives as Highly Potent Respiratory Syncytial Virus Fusion Inhibitors (2015)

A series of imidazolepyridine derivatives were designed and synthesized according to the established docking studies. The imidazopyridine derivatives were found to have good potency and physical-chemical properties. Several highly potent compounds such as 8ji, 8jl, and 8jm were identified with single nanomolar activities. The most potent compound 8jm showed an IC50 of 3 nM, lower microsome clearance and no CYP inhibition. The profile of 8jm appeared to be superior to BMS433771, and supported further optimization.
Grain Size Analysis in Lithium Aluminate Ceramics (2018)

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Is Staging Beneficial for Fowler-Stephens Orchiopexy? A Systematic Review (2010)

Both techniques have a fairly high success rate but 2-stage Fowler-Stephens orchiopexy appears to carry a higher rate of success than the single stage approach (85% vs 80%, OR 2 in favor of 2-stage). Laparoscopic and open techniques had the same success rate. However, the level of evidence of the studies was low, and a study of a more robust design, such as a randomized controlled trial, should be performed.
Many-particle effects in Ge quantum dots investigated by time-resolved capacitance spectroscopy (2000)

Hole emission from self-organized Ge quantum dots with a diameter of ∼70 nm in a Si matrix is investigated by time-resolved capacitance spectroscopy [deep level transient spectroscopy (DLTS)]. A complex DLTS signal is observed and explained in terms of thermally activated emission from localized many-particle states. In particular, a gradually decreasing activation energy is found with increasing hole population. A qualitative understanding of the DLTS signal and the observed activation energies is achieved in terms of many-particle states determined by quantization and Coulomb charging.
γδT cells in Juvenile Idiopathic Arthritis: Higher Percentages of Synovial Vδ1+ and Vγ9+ T Cell Subsets Are Associated with Milder Disease (2011)

The percentage of Vδ1+ and Vγ9+ γδT cells among the SF T cells and their ability to respond to IPP or IL-2 correlated with specific outcomes of JIA, suggesting their role in the immunopathogenesis of this disease.
A Comparison of Crystalline- and Graft Polymer-Based Chemosensors (2003)

Herein, we report a highly sensitive luminescent thin film chemosensor constructed out of a small-molecule donor/acceptor system. Two types of films were compared: one using a small-molecule crystalline donor/acceptor pair and the other using a donor-graft polymer/small-molecule acceptor pair. The acceptor selected for this proof of concept responds to acid, causing its absorption and emission bands to red-shift, which increases spectral overlap with the donor. This increase in overlap greatly enhances energy transfer from the acceptor to the donor. Signal amplification was ascertained by measuring the ratio of acceptor fluorescence when the donor was excited versus direct excitation of the acceptor. Both types of films exhibited large amplification. For the polymeric system, the mechanism of energy migration was investigated by the use of steady-state fluorescence spectroscopy. The mechanism was determined to be dominated by an exciton-hopping process.
Recurrent Glioblastoma Multiforme: ADC Histogram Analysis Predicts Response to Bevacizumab Treatment (2009)

Pretreatment ADC histogram analysis can stratify progression-free survival in bevacizumab-treated patients with recurrent GBM.
Robust decoupling strategy for speed control of permanent magnet synchronous generator in wind energy conversion systems (2011)

The paper presents a robust control strategy for speed tracking problem of variable speed permanent magnet synchronous generator (PMSG) in wind energy conversion system (WECS). A decoupling input, composed of the machine model nonlinearities, is defined to linearize the PMSG model. Then, the angular speed is controlled, through a stabilizing feedback, to follow a trajectory that allows the WECS to operate with maximum power extraction. The turbine torque is unknown to the controller, and its effect on the system is compensated by estimation. Simulation is carried out to verify the performance of the proposed control system.
A novel serogenetic approach determines the community prevalence of celiac disease and informs improved diagnostic pathways (2013)

Screening with TG2 IgA serology and requiring biopsy confirmation caused the community prevalence of CD to be substantially underestimated. Testing for HLA-DQ genes and confirmatory serology could reduce the numbers of unnecessary gastroscopies.
The crystal structures of [Hpy]2[Sb2O BrnCl6 –n] where n= 0, 2, and 4 and Hpy = pyridinium; stabilisation by very strong N–H ⋯ O hydrogen bonds (1986)

Crystal structures have been determined from X-ray diffraction data for [Hpy]2[Sb2OBrnCl6-n] where n= 0 (1), 2 (2), and 4 (3) and Hpy = pyridinium. The compounds are isostructural, crystallising in the monoclinic space group P21/c, with the following cell dimensions: a= 8.816(3), b= 8.61 5(3), c= 28.116(8)Å, β= 112.73(5)° for (1); a= 8.91 9(3), b= 8.81 3(3), c= 28.21 8(8)Å, β= 113.57(4)° for (2); and a= 8.982(3), b= 8.884(3), c= 28.343(8)Å, β= 113.80(4)° for (3). The structures have been solved by Patterson and Fourier methods and refined by full-matrix least squares to R 0.074 (2 652 observed reflections) for (1), 0.075 (2 887) for (2), and 0.066 (2 706) for (3). The compounds all contain a discrete [Sb2OX6]2– anion in which the antimony atoms are triply bridged by one oxygen and two halogen atoms. Both (2) and (3) show halogen disorder. In the former, all six halogen positions are involved but the two bridging positions have ca. 53% occupancy by bromine; in (3) the disorder is between the two sets of terminal positions and the bridging positions are uniquely occupied by bromine. A major feature of the structures and probably a great contributor to the overall stability is a very strong hydrogen bond [2.68(1)Å in (1) and 2.72(1)Å in (2) and (3)] between the bridging oxygen and one of the pyridinium cations.
Albumin Is the Main Nucleophilic Target of Human Plasma: A Protective Role Against Pro-atherogenic Electrophilic Reactive Carbonyl Species? (2008)

The aim of this work was to study the metabolic fate of 4-hydroxy-trans-2-nonenal (HNE) in human plasma, which represents the main vascular site of reactive carbonyl species (RCS) formation and where the main pro-atherogenic target proteins are formed. When HNE was spiked in human plasma, it rapidly disappeared (within 40 s) and no phase I metabolites were detected, suggesting that the main fate of HNE is due to an adduction mechanism. HNE consumption was then monitored in two plasma fractions: low molecular weight plasma protein fractions (<10 kDa; LMWF) and high molecular weight plasma protein fractions (>10 kDa; HMWF). HNE was almost stable in LMWF, while in HMWF it was consumed by almost 70% within 5 min. Proteomics identified albumin (HSA) as the main protein target, as further confirmed by a significantly reduced HNE quenching of dealbuminated plasma. LC-ESI-MS/MS analysis identified Cys34 and Lys199 as the most reactive adduction sites of HSA, through the formation of a Michael and Schiff base adducts, respectively. The rate constant of HNE trapping by albumin was 50.61 ± 1.89 M−1 s−1 and that of Cys34 (29.37 M−1 s−1) was 1 order of magnitude higher with respect to that of GSH (3.81 ± 0.17 M−1 s−1), as explained by molecular modeling studies. In conclusion, we suggest that albumin, through nucleophilic residues, and in particular Cys34, can act as an endogenous detoxifying agent of circulating RCS.
Transmembrane Electron Transfer As Catalyzed by Phospholipid-Linked Manganese Porphyrins (1996)

Phospholipid-linked porphyrins separated by spacer methylene groups (Cn), PE−Cn−MTTP and PE−Cn−MPFPP (n = 0, 5, 11; M = H2, Mn) (Chart 1) were synthesized. The phospholipid-linked porphyrin complexes easily associated with phospholipid bilayers in a manner that allows the porphyrin portion to penetrate the membrane. Ground state transmembrane electron transfer catalyzed by the manganese complex of the phospholipid-linked porphyrins in egg PC and DPPC liposomes revealed that the porphyrin causes a significant accelerated electron transfer especially when n = 11 and that the electron transfer rate was controlled not only by the separated spacer methylene groups between the porphyrin and the phospholipid but also by the phase transition temperature of the lipid bilayers. Comparison of PE−Cn−MnTTP- and PE−Cn−MnPFPP-catalyzed electron transfer is made. Furthermore, the electron transfer was enhanced with an increase of imidazole concentration, implying that imidazole plays an important role in the electron transfer.
Engineering human bone grafts with new macroporous calcium phosphate cement scaffolds (2017)

Bone engineering opens the possibility to grow large amounts of tissue products by combining patient-specific cells with compliant biomaterials. Decellularized tissue matrices represent suitable biomaterials, but availability, long processing time, excessive cost, and concerns on pathogen transmission have led to the development of biomimetic synthetic alternatives. We recently fabricated calcium phosphate cement (CPC) scaffolds with variable macroporosity using a facile synthesis method with minimal manufacturing steps and demonstrated long-term biocompatibility in vitro. However, there is no knowledge on the potential use of these scaffolds for bone engineering and whether the porosity of the scaffolds affects osteogenic differentiation and tissue formation in vitro. In this study, we explored the bone engineering potential of CPC scaffolds with two different macroporosities using human mesenchymal progenitors derived from induced pluripotent stem cells (iPSC-MP) or isolated from bone marrow (BMSC). Biomimetic decellularized bone scaffolds were used as reference material in all experiments. The results demonstrate that, irrespective of their macroporosity, the CPC scaffolds tested in this study support attachment, viability, and growth of iPSC-MP and BMSC cells similarly to decellularized bone. Importantly, the tested materials sustained differentiation of the cells as evidenced by increased expression of osteogenic markers and formation of a mineralized tissue. In conclusion, the results of this study suggest that the CPC scaffolds fabricated using our method are suitable to engineer bone grafts from different cell sources and could lead to the development of safe and more affordable tissue grafts for reconstructive dentistry and orthopaedics and in vitro models for basic and applied research.
Differential detection of pi /4-shifted-DQPSK for digital cellular radio (2002)

A high-capacity digital cellular system is being developed in the US. This system will use filtered pi /4-shifted-DQPSK (differential quaternary phase-shift keying) modulation, achieving a spectral efficiency of 1.62 b/Hz. The BER (bit error rate) performance of this modulation was studied using differential detection. A tangent-type differential detector with an integrated sample and carrier frequency error correction algorithm is presented. Theoretical and simulation BER results are presented for static and flat fading channels. Additional results are provided on the BER sensitivity to Doppler, time delay spread, carrier frequency errors, and DC offsets.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Abstract 16516: Pulsed Field Ablation Reduces Pulmonary Vein Stenosis Risk: An Advanced Model for Assessment of PV Stenosis (2018)

Introduction: Pulmonary vein stenosis (PVS) remains a known morbid risk of catheter ablation for pulmonary vein isolation (PVI) to treat atrial fibrillation. Thermal injury from PVI continues to re...
Improved recovery of admissible stress in domain decomposition methods — application to heterogeneous structures and new error bounds for FETI‐DP (2017)

Summary This paper investigates the question of the building of admissible stress field in a substructured context. More precisely, we analyze the special role played by multiple points. This study leads to (1) an improved recovery of the stress field, (2) an opportunity to minimize the estimator in the case of heterogeneous structures (in the parallel and sequential case), and (3) a procedure to build admissible fields for dual‐primal finite element tearing and interconnecting and balancing domain decomposition by constraints methods leading to an error bound that separates the contributions of the solver and of the discretization. Copyright © 2016 John Wiley &amp; Sons, Ltd.