gebhart/patrepeval huggingface dataset:
NUMERICAL ANALYSIS AND EXPERIMENTAL VALIDATION OF BUBBLE SIZE DISTRIBUTIONS IN TWO-PHASE BUBBLE COLUMN REACTORS (2005)

This paper focuses on the inclusion of a population balance module into a 2D two-phase flow model. An in- house CFD code has been developed adopting a dynamic mixture model for the characterization of the flow pattern in the column. The turbulence closure adopted is in accordance with the work of Lopez de Bertodano [30]. Two concepts are used, one for the liquid shear induced turbulence and a second one for the bubble induced turbulence. The turbulence production due to the gas jets at the inlet zone, determined by the bubbles leaving the holes in the distributor plate and retarding until they reach their terminal velocity, is also accounted for in accordance with the work of Grevskott [33]. The main objective of this study is to validate the combined CFD-population balance model including appropriate closures both for the momentum transfer-, turbulence-, and the coalescence and break-up phenomena. The population model including six bubble size classes is validated with experimental data obtained in our own laboratory for the radial bubble size and volume fraction distributions at two axial levels in the column. The flow model has been validated against experimental data on the radial velocity profiles for both phases at several axial levels.
Ternary complexes in solution. XXIII. Influence of alkyl side chains on the stability of binary and ternary copper(II)-dipeptide complexes (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTernary complexes in solution. XXIII. Influence of alkyl side chains on the stability of binary and ternary copper(II)-dipeptide complexesHelmut. SigelCite this: Inorg. Chem. 1975, 14, 7, 1535–1540Publication Date (Print):July 1, 1975Publication History Published online1 May 2002Published inissue 1 July 1975https://pubs.acs.org/doi/10.1021/ic50149a018https://doi.org/10.1021/ic50149a018research-articleACS PublicationsRequest reuse permissionsArticle Views127Altmetric-Citations48LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Sowing Division: Kurds in the Syrian War (2017)

Kurdish groups, both within Syria and throughout the Middle East, undoubtedly see the Syrian war as an opportunity to advance their goals of self-determination. The Kurdish autonomous region of Rojava is held up as proving the viability and necessity of Kurdish self-rule within any future Syria, with Kurdish leader Idris Nassan declaring that "federalism should be the future." 1 In addition, key events throughout the conflict were seized upon by Kurdish leaders in Turkey and Iraq to generate support for their causes. A strong Kurdish presence at the forefront of resistance to ISIS was used to leverage support from the EU and the United States for Kurdish goals. 2 The PKK (Kurdistan Workers' Party) drew on its close relationship with Syria's armed Kurdish group, the YPG (People's Protection Units), to further increase its influence across the border. Masoud Barzani, president of the Kurdistan
DUKMSVM: A Framework of Deep Uniform Kernel Mapping Support Vector Machine for Short Text Classification (2020)

This paper mainly deals with the problem of short text classification. There are two main contributions. Firstly, we introduce a framework of deep uniform kernel mapping support vector machine (DUKMSVM). The significant merit of this framework is that by expressing the kernel mapping function explicitly with a deep neural network, it is in essence an explicit kernel mapping instead of the traditional kernel function, and it allows better flexibility in dealing with various applications by applying different neural network structures. Secondly, to validate the effectiveness of this framework and to improve the performance of short text classification, we explicitly express the kernel mapping using bidirectional recurrent neural network (BRNN), and propose a deep bidirectional recurrent kernel mapping support vector machine (DRKMSVM) for short text classification. Experimental results on five public short text classification datasets indicate that in terms of classification accuracy, precision, recall rate and F1-score, the DRKMSVM achieves the best performance with the average values of accuracy, precision, recall rate, and F1-score of 87.23%, 86.99%, 86.13% and 86.51% respectively compared to traditional SVM, convolutional neural network (CNN), Naive Bayes (NB), and Deep Neural Mapping Support Vector Machine (DNMSVM) which applies multi-layer perceptron for kernel mapping.
Use of wide-field optical fluorescence for visualization of oral biofilm in a patient with peri-implant mucositis: a new approach (2021)

Peri-implant diseases, caused by bacteria from biofilm related to dental implants, are one of the main causes of late loss of implants. In this sense, peri-implant diseases are divided into peri-implant mucositis, when it affects only the soft tissues, and peri-implantitis, when there is a bone involvement, which can lead to the failure of dental implant therapy. Thus, biofilm removal is essential for peri-implant health, allowing long-term success in implant therapy. To improve the visualization of oral biofilm, which is usually transparent or colorless, disclosing agents have been routinely used. However, disclosing agents have allergenic potential and can cause staining extrinsically in restorative and prosthetic materials, leading to aesthetic impairment. Thus, the use of fluorescence has been studied as an alternative for visualization of oral biofilm. Therefore, this report describes the use of wide-field optical fluorescence for visualization of oral biofilm associated with implants and teeth, in a routine appointment and follow-up of a partially edentulous patient with peri-implant mucositis. In addition, this report showed wide-field optical fluorescence can be used in a clinical routine of care of patients with dental implants. In this sense, wide-field optical fluorescence allowed easy and immediate visualization of the mature oral biofilm for its adequate removal, evaluation of the quality of restoration to sealing of screw access-hole of implant and identification of cariogenic lesions, without risk of allergic reactions or staining of prostheses and restorations.
Parametric Analysis of Factors That Affect Asphalt Binder Foaming Characteristics (2015)

The use of foamed asphalt binder to produce warm-mix asphalt has increased significantly during the past few years. It is recognized that (1) foaming characteristics of the binder influence the workability of the asphalt mix, and (2) different asphalt binders tend to foam differently with all other factors being the same. The causes for the latter are relatively less explored and is the focus of this paper. The research reproted in this paper investigated the influence of the properties of asphalt binder on its foaming characteristics. A physical model for expansion of asphalt binder foam based on foam physics was used to quantify the effect of water content, temperature, surface tension, and liquid additive (through its effect on surface tension) on the expansion ratio of asphalt binder foam. Analysis of results demonstrates that the bubble size distribution (up to a certain limit) does not directly dictate the maximum expansion ratio of the asphalt binder foam. The analysis also shows that only a fraction of the water added to the binder is effective in creating the foam. The effective water content was strongly correlated with the surface tension of the binder, which was also substantiated by the solubility theory. Surface tension of the asphalt binder was also found to be strongly correlated to the stability of the foam. Foam characteristics of binders modified with additives also demonstrated that stability and expansion of foams can be significantly improved using carefully selected liquid additives.
Mäßigung statt Neuanfang: Iran nach den Präsidentschaftswahlen 2013 (2013)

Die elften iranischen Präsidentschaftswahlen vom 14. Juni 2013 sind zwar kein Meilenstein auf dem Weg in Richtung einer Demokratisierung Irans, aber ein wichtiger Indikator für die politische Mäßigung bei gleichzeitiger Stabilisierung des Regimes. Mittlerweile zeichnet sich ab, dass der neue Präsident mit Vertretern des gesamten politischen Spektrums zusammenarbeiten wird. Querschüsse von Seiten politischer Opponenten sind diesmal nicht zu erwarten, da ein Teil der Prinzipalisten integriert und ihr extremistischer Flügel marginalisiert wurde. Auf internationaler Ebene darf man auf eine gemäßigte, konstruktive Außenpolitik hoffen. Der Neuanfang der Beziehungen mit dem Westen muss freilich erst gelingen. (Autorenreferat)
Null response to a large signal transient in an augmented dc-dc converter: A geometric approach (2010)

The maximum closed-loop bandwidth of a dc-dc converter is restricted to a fraction of its switching frequency, while governed by a conventional pulse-width-modulation (PWM) technique. Even an advanced geometric control is limited by its internal slew rate. The bandwidth can be made close to (even higher than) the switching frequency through converter augmentation; however, it requires a proper control algorithm and circuit arrangements. This paper considers methods of controlling both augmented buck and boost converters. An augmented boost converter topology is also proposed. The main switch is controlled through fixed-frequency PWM control, and augmented switches are controlled through a bang-bang control. The open-loop small-signal analysis is carried out using a frequency domain approach. Minimum-time transient recovery is achieved using a finite set of augmented resistances and dynamically varying voltage hysteresis bands. It is possible to achieve null response in the sense of ripple band to the large-signal transient.
Microstructure and electrical properties of epitaxial SrBi2Nb2O9And SrBi2Ta2O9films (2001)

Abstract SrBi2Nb2O9 (and in some cases SrBi2Ta2O9) epitaxial thin films were deposited on (001), (110), and (111) SrTiO3 substrates by pulsed laser deposition (PLD), both with and without epitaxial SrRuO3 bottom electrodes. Films grow epitaxially with the c-axis inclined by 0°, 45°, and 57° from the substrate surface normal, respectively. Greater tilts of the c-axis into the plane of the substrate surface provide a greater component of the polar axis (the a-axis of the orthorhombic unit cell) perpendicular to the substrate surface, leading to increased remanent polarization (P r) values. Portions of the same films used for electrical characterization were examined by transmission electron microscopy (TEM). Films have a single c-axis tilt angle and are fully crystalline with no observable second-phase inclusions. All films are observed to have a high density of out-of-phase boundaries (OPBs).
The V-ATPase-Inhibitor Archazolid Abrogates Tumor Metastasis via Inhibition of Endocytic Activation of the Rho-GTPase Rac1 (2012)

The abundance of the multimeric vacuolar ATP-dependent proton pump, V-ATPase, on the plasma membrane of tumor cells correlates with the invasiveness of the tumor cell, suggesting the involvement of V-ATPase in tumor metastasis. V-ATPase is hypothesized to create a proton efflux leading to an acidic pericellular microenvironment that promotes the activity of proinvasive proteases. An alternative, not yet explored possibility is that V-ATPase regulates the signaling machinery responsible for tumor cell migration. Here, we show that pharmacologic or genetic reduction of V-ATPase activity significantly reduces migration of invasive tumor cells in vitro. Importantly, the V-ATPase inhibitor archazolid abrogates tumor dissemination in a syngeneic mouse 4T1 breast tumor metastasis model. Pretreatment of cancer cells with archazolid impairs directional motility by preventing spatially restricted, leading edge localization of epidermal growth factor receptor (EGFR) as well as of phosphorylated Akt. Archazolid treatment or silencing of V-ATPase inhibited Rac1 activation, as well as Rac1-dependent dorsal and peripheral ruffles by inhibiting Rab5-mediated endocytotic/exocytotic trafficking of Rac1. The results indicate that archazolid effectively decreases metastatic dissemination of breast tumors by impairing the trafficking and spatially restricted activation of EGFR and Rho-GTPase Rac1, which are pivotal for directed movement of cells. Thus, our data reveals a novel mechanism underlying the role of V-ATPase in tumor dissemination.
A Phosphite Dehydrogenase Variant with Promiscuous Access to Nicotinamide Cofactor Pools Sustains Fast Phosphite-Dependent Growth of Transplastomic Chlamydomonas reinhardtii (2020)

Heterologous expression of the NAD<sup>+</sup>-dependent phosphite dehydrogenase (PTXD) bacterial enzyme from <i>Pseudomonas stutzerii</i> enables selective growth of transgenic organisms by using phosphite as sole phosphorous source. Combining phosphite fertilization with nuclear expression of the <i>ptxD</i> transgene was shown to be an alternative to herbicides in controlling weeds and contamination of algal cultures. Chloroplast expression of <i>ptxD</i> in <i>Chlamydomonas reinhardtii</i> was proposed as an environmentally friendly alternative to antibiotic resistance genes for plastid transformation. However, PTXD activity in the chloroplast is low, possibly due to the low NAD<sup>+</sup>/NADP<sup>+</sup> ratio, limiting the efficiency of phosphite assimilation. We addressed the intrinsic constraints of the PTXD activity in the chloroplast and improved its catalytic efficiency in vivo via rational mutagenesis of key residues involved in cofactor binding. Transplastomic lines carrying a mutagenized PTXD version promiscuously used NADP<sup>+</sup> and NAD<sup>+</sup> for converting phosphite into phosphate and grew faster compared to those expressing the wild type protein. The modified PTXD enzyme also enabled faster and reproducible selection of transplastomic colonies by directly plating on phosphite-containing medium. These results allow using phosphite as selective agent for chloroplast transformation and for controlling biological contaminants when expressing heterologous proteins in algal chloroplasts, without compromising on culture performance.
11-Dehydro-thromboxane B2, a Stable Thromboxane Metabolite, Is a Full Agonist of Chemoattractant Receptor-homologous Molecule Expressed on TH2 Cells (CRTH2) in Human Eosinophils and Basophils (2004)

Thromboxane (TX) A(2), a cyclooxygenase-derived mediator involved in allergic responses, is rapidly converted in vivo to a stable metabolite, 11-dehydro-TXB(2), which is considered to be biologically inactive. In this study, we found that 11-dehydro-TXB(2), but not the TXA(2) analogue U46,619 or TXB(2), activated eosinophils and basophils, as assayed by flow cytometric shape change. 11-Dehydro-TXB(2) was also chemotactic for eosinophils but did not induce, nor inhibit, platelet aggregation. Chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) is an important chemoattractant receptor expressed by eosinophils, basophils, and TH2 lymphocytes, and prostaglandin (PG)D(2) has been shown to be its principal ligand. 11-Dehydro-TXB(2) induced calcium flux mainly from intracellular stores in eosinophils, and this response was desensitized after stimulation with PGD(2) but not other eosinophil chemoattractants. Shape change responses of eosinophils and basophils to 11-dehydro-TXB(2) were inhibited by the thromboxane (TP)/CRTH2 receptor antagonist ramatroban, but not the selective TP antagonist SQ29,548, and were insensitive to pertussis toxin. The phospholipase C inhibitor U73,122 attenuated both 11-dehydro-TXB(2)- and PGD(2)-induced shape change. 11-Dehydro-TXB(2) also induced the chemotaxis of BaF/3 cells transfected with hCRTH2 but not naive BaF/3 cells. At a threshold concentration, 11-dehydro-TXB(2) had no antagonistic effect on CRTH2-mediated responses as induced by PGD2. These data show that 11-dehydro-TXB(2) is a full agonist of the CRTH2 receptor and hence might cause CRTH2 activation in cellular contexts where PGD-synthase is not present. Given its production in the allergic lung, antagonism of the 11-dehydro-TXB(2)/CRTH2axis may be of therapeutic relevance.
Designing computer systems with MEMS-based storage (2000)

For decades the RAM-to-disk memory hierarchy gap has plagued computer architects. An exciting new storage technology based on microelectromechanical systems (MEMS) is poised to fill a large portion of this performance gap, significantly reduce system power consumption, and enable many new applications. This paper explores the system-level implications of integrating MEMS-based storage into the memory hierarchy. Results show that standalone MEMS-based storage reduces I/O stall times by 4-74X over disks and improves overall application runtimes by 1.9-4.4X. When used as on-board caches for disks, MEMS-based storage improves I/O response time by up to 3.5X. Further, the energy consumption of MEMS-based storage is 10-54X less than that of state-of-the-art low-power disk drives. The combination of the high-level physical characteristics of MEMS-based storage (small footprints, high shock tolerance) and the ability to directly integrate MEMS-based storage with processing leads to such new applications as portable gigabit storage systems and ubiquitous active storage nodes.
Surface Properties and Cell Response of Bioactive Thermally Grown TiO<sub>2</sub> Nanofibers (2014)

Titania nanofiber (TiO 2 NFs) arrays were fabricated in situ on a Ti-6Al-4V substrate by an oxidation process. Their surface morphology, crystallographic structure, surface roughness and wettability were characterized, as well as their in vitro interaction with bovine articular chondrocytes at different time points. Results showed that TiO 2 NFs possessed greater surface roughness, hydrophilicity and degree of crystallinity. The in vitro cell studies revealed that TiO 2 NFs substrate triggers enhanced cell adhesion, proliferation and extracellular matrix (ECM) formation compared to the untreated control sample. These results showed that chondrocytes have an affinity to the nanofibrous substrate surface and thus we suggest that such surfaces are suited to be used as an implant designed for cartilage growth.
Whole-genome sequencing of Atacama skeleton shows novel mutations linked with dysplasia (2018)

Over a decade ago, the Atacama humanoid skeleton (Ata) was discovered in the Atacama region of Chile. The Ata specimen carried a strange phenotype-6-in stature, fewer than expected ribs, elongated cranium, and accelerated bone age-leading to speculation that this was a preserved nonhuman primate, human fetus harboring genetic mutations, or even an extraterrestrial. We previously reported that it was human by DNA analysis with an estimated bone age of about 6-8 yr at the time of demise. To determine the possible genetic drivers of the observed morphology, DNA from the specimen was subjected to whole-genome sequencing using the Illumina HiSeq platform with an average 11.5× coverage of 101-bp, paired-end reads. In total, 3,356,569 single nucleotide variations (SNVs) were found as compared to the human reference genome, 518,365 insertions and deletions (indels), and 1047 structural variations (SVs) were detected. Here, we present the detailed whole-genome analysis showing that Ata is a female of human origin, likely of Chilean descent, and its genome harbors mutations in genes (<i>COL1A1</i>, <i>COL2A1</i>, <i>KMT2D</i>, <i>FLNB</i>, <i>ATR</i>, <i>TRIP11</i>, <i>PCNT</i>) previously linked with diseases of small stature, rib anomalies, cranial malformations, premature joint fusion, and osteochondrodysplasia (also known as skeletal dysplasia). Together, these findings provide a molecular characterization of Ata's peculiar phenotype, which likely results from multiple known and novel putative gene mutations affecting bone development and ossification.
Modeling diffraction from an edge between surfaces with different materials (2004)

In this paper we present the measured data of the diffraction of one single edge. The data consists of cases where the surfaces, forming a diffractive edge, are covered with highly absorptive material. The measured results show that the effect of absorptive material in surfaces does not change the diffraction phenomenon prominently. This fact allows us to suggest that in several practical room acoustics design problems the effect of material absorption in edge diffraction might be neglected.
Styrtransmission för bandfordon (2006)

The purpose of this master thesis is to construct a steering transmission, for a tracked vehicle, containing two hydraulic circuits which are connected. The steering transmission should be mechanical to avoid steer-by-wire. BAE Systems Hägglunds has in an earlier study examined a system with two hydraulic pumps and one hydraulic motor, but the safety of the system wasn’t sufficient. To achieve sufficient redundancy there must be two hydraulic motors, which are controlled separately. When the two systems are connected in one point, this point is a critical part of the system because it directly affects both circuits. If one of the hydraulic circuits fails the other should be able to operate independently as a steering transmission. This is possible by disconnecting the defect circuit with a tooth clutch. Separating the systems can also be done with a differential. Using a differential means that the use of a brake or a bidirectional no-back control is necessary to prevent the drive shaft from going backwards. The tracked vehicle should be able to make a pivot turn in less then 12 s, with a vehicle weight of 17500 kg. That combined with lack of space set high demands on the hydraulic system. The hydraulic components which are used must withstand pressure up to 450 bar and flows up to 170 l/min. The hydraulic pumps must cope with the drive circuit’s speed of 4400 rpm. The hydraulic pumps must have a variable displacement so that the vehicle will be able to turn in both directions. The hydraulic motor have a fixed displacement, this makes construction of the mechanical linkage from the steering wheel to the hydraulic system easier. Push/pull wires will be used as linkage. The system can easily be redimensioned to fit a heavier vehicle. It’s easy to shift the concept to a differential style if any problems appear during testing. The system is a part of a component test that will be carried out during 2006.