gebhart/patrepeval huggingface dataset:
Molecular Quantum-Dot Cellular Automata (2003)

Molecular electronics is commonly conceived as reproducing diode or transistor action at the molecular level. The quantum-dot cellular automata (QCA) approach offers an attractive alternative in which binary information is encoded in the configuration of charge among redox-active molecular sites. The Coulomb interaction between neighboring molecules provides device-device coupling. No current flow between molecules is required. We present an ab initio analysis of a simple molecular system which acts as a molecular QCA cell. The intrinsic bistability of the charge configuration results in dipole or quadrupole fields which couple strongly to the state of neighboring molecules. We show how logic gates can be implemented. We examine the role of the relaxation of nuclear coordinates in the molecular charge reconfiguration.
Coupling study of a rotary Capacitive Power Transfer system (2009)

In this paper a new technology termed Capacitive Power Transfer (CPT) is investigated to achieve contactless power transfer. Compared to traditional Inductive Power Transfer (IPT) technology, the advantages of CPT include the ability to supply power through metal barriers, reducing standing power losses, and alleviating EMI (Electromagnetic Interference). Electric coupling is a key part in a CPT system as it dominates the maximum power transfer capacity and the performance of the system. Different applications can have very different coupling structures and power level requirements. This paper proposes two types of coupling structures, disk and cylinder, for a rotary CPT system application. The system frequency, maximum output power, and power losses based on the cylindrical structure which has a larger coupling capacitance are analyzed. Simulation and experimental studies are carried out to verify the proposed coupling configurations.
Subcellular Localization of Uro-Angiographic Contrast by 125I-labeled Media (1980)

Various uro-angiographic contrast media have been injected in the rabbit. The partition at the organ level and in subcellular fraction has been studied. Blood enzymatic inhibition with specific enzymatic systems is reported.
Carotenoids and Their Fatty Acid Esters of Spiny Lobster Panulirus japonicus (2008)

Carotenoids and their fatty acid esters in the carapace of the spiny lobster Panulirus japonicus were investigated. Fatty acid esters of astaxanthin, adonixanthin, and pectenolone were characterized by (1)H-NMR and FAB-MS. The acylated position of adonixanthin and pectenolone monoesters was determined to be a hydroxy group at C-3' by (1)H-NMR. The fatty acids esterified with these carotenoids were identified as C22:6, C20:4, C20:5, C18:0, C18:1, C17:0, C16:0, C16:1, C14:0, and C12:0 from FAB-MS spectral data. Furthermore, 2,3-didehydrocanthaxanthin (4) was first identified as a natural product.
Fluorescence anisotropy measurement of green fluorescent protein for nano-environment probing (2013)

Fluorescence anisotropy of GFP molecules, suspended in solution and immobilized on a glass substrate, was measured to investigate the application for nano-environment probe. Nano-environment around living cell is of interest in relation with wide range of fields, such as cell interaction in cancer tissue, nerve signal transmission and so on. However, nano-environment is so sensitive to the interference of probe or measurement itself. For example, measurement of neuron potential is performed by inserting electrode to the tissue, or staining with toxic dye. For measurement of nano-environment GFP has some superior characteristics. GFP molecule itself is soluble protein and has little toxicity to the cell. It need no prosthetic group for fluorescent activity, and easily introduced by genetic method. We investigated the fluorescence anisotropy of GFP for probing molecular motion in the nano space. Anisotropy of free molecule in solution was compatible with theoretical value. Immobilized molecule, on the contrary, showed higher anisotropy than theoretically expected. This extraordinary value may come from hydrophobic interaction of GFP with glass surface, that can be utilized for nano-probing.
RTP Payload Format for Reed Solomon FEC (2011)

This document defines an RTP payload format for the Forward Error
Correction (FEC) that uses Reed-Solomon codes. The format defined by
this document enables the protection of source media encapsulated in
RTP with one or more repair flows and is based on the FEC framework
(described in [I-D.ietf-fecframe-framework]) and the SDP Elements for
FEC Framework (described in [I-D.ietf-fecframe-sdp-elements]). The
Reed-Solomon codes used in this document belong to the class of
Maximum Distance Separable (MDS) codes which means they offer optimal
protection against random and bursty packet losses.
Report on Wines (1937)

Journal Article Report on Wines Get access B G Hartmann B G Hartmann Associate Referee U. S. Food and Drug Administration, Washington, D. C Search for other works by this author on: Oxford Academic Google Scholar Journal of Association of Official Agricultural Chemists, Volume 20, Issue 2, 1 May 1937, Pages 149–151, https://doi.org/10.1093/jaoac/20.2.149 Published: 17 February 2020
Minimally invasive spine surgery for adult degenerative lumbar scoliosis (2014)

The results of this study suggest that surgeons are offering patients open surgery or MIS depending on their age and the severity of their deformity. Greater sagittal and coronal correction was noted in the XLIF versus decompression only MIS groups. Larger Cobb angles, greater sagittal imbalance, and higher reoperation rates were found in studies reporting the use of open fusion with osteotomy. Although complication rates did not significantly differ between groups, these data are difficult to interpret given the heterogeneity in reporting complications between studies.
Bioluminescence measurement of primary bile acids using immobilized 7 alpha-hydroxysteroid dehydrogenase: application to serum bile acids (1982)

A simple, rapid, and sensitive bioluminescence method for measuring primary bile acids has been developed and validated. The method is based on enzymatic dehydrogenation of bile acids using a bacterial 7 alpha-hydroxysteroid dehydrogenase that is co-immobilized on Sepharose 4B beads with NADH:FMN oxidoreductase and a bacterial luciferase. The assay is specific for 7 alpha-hydroxy bile acids and has a detection limit of 0.5 pmol/tube, with a linear range of 0.5-50 pmol/tube. The assay shows good precision (6-8% intra-assay; 8-10% inter-assay). The values obtained with the bioluminescence assay showed good agreement with those obtained by gas-liquid chromatography, radioimmunoassay, or endpoint enzymatic assays. When applied to the measurement of serum bile acids, there was no interference from serum albumin, and the effect of other dehydrogenase activity in serum could be eliminated by heating the sample prior to assay. Since the method is rapid (1 minute), extremely sensitive (requires only 10 microliters of serum), and specific, it appears to be the best method currently available for the measurement of serum primary bile acids.
Digital control law using a novel load current estimator principle for improved transient response (2008)

A method for the early detection of load transients using a current estimator for VR applications is presented. This technique combined with a new charge-balanced digital control law can improve the dynamic response to fast load transients. The key advantage of this new approach is the early detection of load transients which is independent of ADC sampling, where most existing solutions incorporate relatively expensive, complex and energy consuming high-speed ADCs. The presented method significantly reduces the inherent delay associated with fixed sampling detection in the control loop. The load current estimation during transient is critical for improved transient performance and allows the possibility of using a charge-balanced control law. Unlike existing algorithms, the presented control law is capable of implementing non-zero load lines required for VRMs. A full description of this control law is detailed. The current estimator technique and the charge-balanced digital control law are critically assessed using Matlab/Simulink. The resulting transient behaviour gives a significant improvement over conventional control schemes.
Controllable Catalysis with Nanoparticles: Bimetallic Alloy Systems and Surface Adsorbates (2016)

Transition-metal nanoparticles are privileged materials in catalysis due to their high specific surface areas and abundance of active catalytic sites. Although many of these catalysts are quite useful, we are only beginning to understand the underlying catalytic mechanisms. Opening the “black box” of nanoparticle catalysis is essential to achieve the ultimate goal of catalysis by design. In this Perspective, we highlight recent work addressing the topic of controlled catalysis with bimetallic alloy and “designer” adsorbate-stabilized metal nanoparticles.
Deep learning for FTIR histology: leveraging spatial and spectral features with convolutional neural networks (2018)

Current methods for cancer detection rely on tissue biopsy, chemical labeling/staining, and examination of the tissue by a pathologist. Though these methods continue to remain the gold standard, they are non-quantitative and susceptible to human error. Fourier transform infrared (FTIR) spectroscopic imaging has shown potential as a quantitative alternative to traditional histology. However, identification of histological components requires reliable classification based on molecular spectra, which are susceptible to artifacts introduced by noise and scattering. Several tissue types, particularly in heterogeneous tissue regions, tend to confound traditional classification methods. Convolutional neural networks (CNNs) are the current state-of-the-art in image classification, providing the ability to learn spatial characteristics of images. In this paper, we demonstrate that CNNs with architectures designed to process both spectral and spatial information can significantly improve classifier performance over per-pixel spectral classification. We report classification results after applying CNNs to data from tissue microarrays (TMAs) to identify six major cellular and acellular constituents of tissue, namely adipocytes, blood, collagen, epithelium, necrosis, and myofibroblasts. Experimental results show that the use of spatial information in addition to the spectral information brings significant improvements in the classifier performance and allows classification of cellular subtypes, such as adipocytes, that exhibit minimal chemical information but have distinct spatial characteristics. This work demonstrates the application and efficiency of deep learning algorithms in improving the diagnostic techniques in clinical and research activities related to cancer.
Strain in Silica-Supported Ga (III) Sites: Neither Too Much nor Too Little for Propane Dehydrogenation Catalytic Activity (2020)

&lt;p&gt;Well-defined Ga(III) sites on SiO&lt;sub&gt;2&lt;/sub&gt; are highly active, selective, and stable catalysts in the propane dehydrogenation reaction. In this contribution, we evaluate the catalytic activity towards propane dehydrogenation of tri-coordinated and tetra-coordinated Ga(III) sites on SiO&lt;sub&gt;2&lt;/sub&gt; by means of first principles calculations using realistic amorphous periodic SiO&lt;sub&gt;2&lt;/sub&gt;models. We evaluated the three reaction steps in propane dehydrogenation, namely the C-H activation of propane to form propyl, the beta-hydride elimination transfer to form propene, and a Ga-hydride, and the H-H coupling to release H&lt;sub&gt;2&lt;/sub&gt;, regenerating the initial Ga-O bond and closing the catalytic cycle. Our work shows how Brønsted-Evans-Polanyi relationships are followed for these three reaction steps on Ga(III) sites on SiO&lt;sub&gt;2&lt;/sub&gt; and highlights the role of the strain of the reactive Ga-O pairs on such sites of realistic amorphous SiO&lt;sub&gt;2&lt;/sub&gt; models. While highly strained sites are very reactive sites for the initial C-H activation, they are more difficult to regenerate. The corresponding less strained sites are not reactive enough, pointing to the need of a right balance in strain to be an effective site for propane dehydrogenation. Overall, our work provides an understanding of the intrinsic activity of acidic Ga single sites towards the propane dehydrogenation reaction and paves the road towards the design and prediction of better single-site catalysts on SiO&lt;sub&gt;2 &lt;/sub&gt;for the propane dehydrogenation reaction.&lt;/p&gt;
The neuropathology and pathogenesis of HIV brain infection (1996)

Neurological disorders, notably a dementia, are central to the outcome and medical management of patients with AIDS. These disorders are the consequence of both a secondary immunosuppression and a distinct, primary pathological process due directly to the virus. This pathological process involves a range of inflammatory disorders in association with synaptic, dendritic and neuronal degeneration. Recent evidence indicates that the degeneration is a consequence of HIV derived factors and of alterations in the expression of host factors. Furthermore, the degeneration may have a final common pathway, involving alterations in calcium homeostasis and ending with neuronal loss through apoptosis. In this review we will concentrate on the primary damage due to the HIV virus and describe its relationship to the development of clinical dementia. The timing of this damage and the mechanisms by which it occurs will be outlined.
Breadth-first crawling yields high-quality pages (2001)

Article Breadth-first crawling yields high-quality pages Share on Authors: Marc Najork Compaq Systems Research Center, 130 Lytton Avenue, Palo Alto, CA Compaq Systems Research Center, 130 Lytton Avenue, Palo Alto, CAView Profile , Janet L. Wiener Compaq Systems Research Center, 130 Lytton Avenue, Palo Alto, CA Compaq Systems Research Center, 130 Lytton Avenue, Palo Alto, CAView Profile Authors Info & Claims WWW '01: Proceedings of the 10th international conference on World Wide WebMay 2001 Pages 114–118https://doi.org/10.1145/371920.371965Online:01 April 2001Publication History 187citation1,650DownloadsMetricsTotal Citations187Total Downloads1,650Last 12 Months60Last 6 weeks4 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Dietary polyphenols decrease glucose uptake by human intestinal Caco‐2 cells (2005)

The effect of different classes of dietary polyphenols on intestinal glucose uptake was investigated using polarised Caco-2 intestinal cells. Glucose uptake into cells under sodium-dependent conditions was inhibited by flavonoid glycosides and non-glycosylated polyphenols whereas aglycones and phenolic acids were without effect. Under sodium-free conditions, aglycones and non-glycosylated polyphenols inhibited glucose uptake whereas glycosides and phenolic acids were ineffective. These data suggest that aglycones inhibit facilitated glucose uptake whereas glycosides inhibit the active transport of glucose. The non-glycosylated dietary polyphenols appear to exert their effects via steric hindrance, and (-)-epigallochatechingallate, (-)-epichatechingallate and (-)-epigallochatechin are effective against both transporters.
Immunization. Update: search for an AIDS vaccine. (2000)

Identifying a successful HIV preventive vaccine is among the highest research priorities of the US NIH. While therapies for HIV have brought hope to those who are already HIV-infected, stopping the worldwide epidemic will require safe, effective HIV vaccines. Here, we describe scientific and other obstacles to attaining that goal and provide a brief synopsis of clinical trial results, recent preclinical results, and future priorities.
Release of Adenine Nucleotides in the Dog Blood Plasma By a Corbicula Extract (1957)

In traportal as well as systemic venous injection of a corbicula extract causes an appearance of substances, showing a maximum absorption at 260 mμ, in the dog blood plasma obtained from the hepatic and femoral vein immediately after the injection. They were considered as ad enine nucleotides by paper chromatography and known to originate chiefly in the liver by the fact that a higher concentration is reached in the hepatic venous plasma by either route of injection.
Stability of Cephaloridine and Cephalothin to Staphylococcal Penicillinase (1967)

SUMMARY The rates of destruction of benzylpenicillin, cephaloridine, cephalothin and (in some cases) cloxacillin by cocci from induced cultures of 17 strains of Staphylococcus aureus were measured. Rates of destruction of cephaloridine, relative in each case to those of benzylpenicillin, by the 10 methicillin-resistant strains were not significantly different from those by the 7 methicillin-sensitive strains. V max for cephaloridine and cephalothin were about 0·2 % and 0·009 %, respectively, that for benzylpenicillin; cloxacillin was destroyed still more slowly. The inactivation of the cephalosporins is almost certainly brought about by the action of penicillinase. Notwithstanding its greater stability to staphylococcal penicillinase, cephalothin is less effective than cephaloridine at suppressing the growth of the methicillin-resistant strains, although there is cross-resistance between methicillin, cloxacillin, cephalothin and cephaloridine.
Enzymatic Analysis of Isomeric Trithymidylates Containing Ultraviolet Light-induced Cyclobutane Pyrimidine Dimers (1989)

Our recent findings suggest that enzymatic hydrolysis of the intradimer phosphodiester bond may constitute the initial step in the repair of UV light-induced cyclobutane pyrimidine dimers in human cells. To examine the susceptibility of this phosphodiester linkage to enzyme-mediated hydrolysis, the trinucleotide d-Tp-TpT was UV-irradiated and the two isomeric compounds containing a cis-syn-cyclobutane dimer were isolated by high performance liquid chromatography and treated with various deoxyribonucleases. Snake venom phosphodiesterase hydrolyzed only the 3'-phosphodiester group in the 5'-isomer (d-T less than p greater than TpT) but was totally inactive toward the 3'-isomer (d-TpT less than p greater than T). In contrast, calf spleen phosphodiesterase only operated on the 3'-isomer by cleaving the 5'-internucleotide bond. Kinetic analysis revealed that (i) the activity of snake venom phosphodiesterase was unaffected by a dimer 5' to a phosphodiester linkage, (ii) the action of calf spleen phosphodiesterase was partially inhibited by a dimer 3' to a phosphodiester bond, and (iii) Escherichia coli phr B-encoded DNA photolyase reacted twice as fast with d-T less than p greater than TpT as with d-TpT less than p greater than T. Mung bean nuclease, nuclease S1, and nuclease P1 all cleaved the 5'-internucleotide linkage, but not the intradimer phosphodiester bond, in d-TpT less than p greater than T. Both phosphate groups in d-T less than p greater than TpT were refractory to mung bean nuclease or nuclease S1. Incubation of d-T less than p greater than TpT with nuclease P1, however, generated the novel compound dT less than greater than d-pTpT containing a severed intradimer phosphodiester linkage. Accordingly, nuclease P1 represents the first purified enzyme known to hydrolyze an intradimer phosphodiester linkage.
Agile reactive navigation for a non‐holonomic mobile robot using a pixel processor array (2021)

Abstract This paper presents an agile reactive navigation strategy for driving a non‐holonomic ground vehicle around a pre‐set course of gates in a cluttered environment using a low‐cost processor array sensor. This enables machine vision tasks to be performed directly upon the sensor's image plane, rather than using a separate general‐purpose computer. The authors demonstrate a small ground vehicle running through or avoiding multiple gates at high speed using minimal computational resources. To achieve this, target tracking algorithms are developed for the Pixel Processing Array and captured images are then processed directly on the vision sensor acquiring target information for controlling the ground vehicle. The algorithm can run at up to 2000 fps outdoors and 200 fps at indoor illumination levels. Conducting image processing at the sensor level avoids the bottleneck of image transfer encountered in conventional sensors. The real‐time performance of on‐board image processing and robustness is validated through experiments. Experimental results demonstrate the algorithm's ability to enable a ground vehicle to navigate at an average speed of 2.20 m/s for passing through multiple gates and 3.88 m/s for a ‘slalom’ task in an environment featuring significant visual clutter.
Computer‐aided design of millimeter‐wave Gunn oscillator in suspended strip line with evanescent guide termination (1999)

This paper presents the computer-aided design (CAD) of a Gunn diode oscillator in a suspended strip line terminated in a short inductive line length followed by a section of an evanescent mode waveguide. With the diode-equivalent circuit parameters known approximately, this model enables the minimization of the experimental iterations needed for finalizing the oscillator design for maximum power output. A typical 35 GHz oscillator realized with the help of this CAD offers a stable power output which is nearly the maximum rated power of the Gunn diode. ©1999 John Wiley & Sons, Inc. Microwave Opt Technol Lett 20: 156–160, 1999.
Enemy or partner: Relationship between intronic micrornas and their host genes (2012)

In the past several years, microRNAs have been identified as a class of important regulators of gene expression. One hot topic in the microRNA field is the location of microRNA genes. Most microRNAs are called intronic microRNAs, which are encoded in the introns of coding or non-coding genes. Some research studies have shown that intronic miRNAs coexpress and act similarly to their host genes; however, other research studies have suggested that their level of expression and function are opposite to that of their host genes. Intronic microRNAs have been reported to play an antagonistic or synergetic role as an enemy or a partner of their host genes. Elucidation of the relationship between intronic microRNAs and their host genes will facilitate a deeper understanding of gene expression and the function of introns. This mini review will discuss recent research addressing intronic microRNAs and their host genes.