gebhart/patrepeval huggingface dataset:
Study on improvement of the performance parameters of a novel 0.41–0.47 THz on-chip antenna based on metasurface concept realized on 50 μm GaAs-layer (2020)

A feasibility study is presented on the performance parameters of a novel on-chip antenna based on metasurface technology at terahertz band. The proposed metasurface on-chip antenna is constructed on an electrically thin high-permittivity gallium arsenide (GaAs) substrate layer. Metasurface is implemented by engraving slot-lines on an array of 11 × 11 circular patches fabricated on the top layer of the GaAs substrate and metallic via-holes implemented in the central patch of each row constituting the array, which connects the patch to the leaky-wave open-ended feeding slot-lines running underneath the patches. The slot-lines are connected to each other with a slit. A waveguide port is used to excite the array via slot-lines that couple the electromagnetic energy to the patches. The metasurface on-chip antenna is shown to exhibit an average measured gain in excess of 10 dBi and radiation efficiency above 60% over a wide frequency range from 0.41 to 0.47 THz, which is significant development over other on-chip antenna techniques reported to date. Dimensions of the antenna are 8.6 × 8.6 × 0.0503 mm<sup>3</sup>. The results show that the proposed GaAs-based metasurface on-chip antenna is viable for applications in terahertz integrated circuits.
A novel DNA-binding protein fromCampylobacter jejunibacteriophage NCTC12673 (2015)

We previously suggested that the double-stranded genomic DNA of Campylobacter jejuni bacteriophage NCTC12673 was complexed with proteins. Mass spectrometry of peptides obtained from tryptic digests of purified phage DNA indicated that phage protein Gp001 co-purified with the DNA. Gp001 is an acidic protein that lacks any obvious homology or conserved domains found in known DNA-binding proteins. The DNA-binding ability of recombinant Gp001 was examined using an electrophoretic mobility shift assay. Slow DNA-Gp001 complex formation was observed at pH 5.5, but not at neutral or basic pH. This nucleoprotein complex had difficulty entering agarose gels used in the assay while proteinase K pretreatment released the DNA from the complex. No mobility shift was observed when the DNA was immediately subjected to electrophoresis after mixing with Gp001, even if both components were separately pre-incubated at pH 5.5. The complexed DNA was unable to transform chemically competent Escherichia coli cells and was less susceptible to degradation by nucleases. The formation of Gp001-DNA complexes at low pH may provide a mechanism for maintaining DNA integrity while the phage pursues its host through the gastrointestinal tract. Also, this feature can potentially be used to improve DNA delivery protocols applied in gene therapy.
A high performance FPGA with hierarchical interconnection structure (2002)

To overcome the low speed and low density problems in the FPGAs, we must reduce the number of switches used in the routing paths without sacrificing the routability for an FPGA. A hierarchical interconnection architecture for field programmable gate array (FPGA) is described. In every level of the hierarchy, logic blocks or cluster of logic blocks are connected together with switch blocks. Experiments on benchmark circuits are shown. It can be seen that significant improvement on performance is achieved.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Lung Cancer Markers as Detected by Monoclonal Antibodies (1985)

Over 120,000 new cases of lung cancer occur annually in the United States and the incidence is increasing (Silverberg, 1982). Ninety percent of those individuals with lung cancer die from their disease, making lung cancer the single most lethal malignancy, accounting for 25% of all cancer fatalities (Silverberg, 1982). Other than surgical resection of early lesions, the effectiveness of most other forms of therapy has been marginal (Aisner and Hansen, 1981; Minna et al., 1982). In considering lung cancer, one must deal with at least four major histologies, sharing variable degrees of relatedness (Matthews, 1981; Gazdar, 1984). Clinically, the distinction is often made between small cell lung cancer (SCLC) and the remaining histologies collectively referred to as the nonsmall-cell lung cancers (NSCLC) due to the distinct natural history and response to therapy of the two different groups (Cohen, 1978; Gazdar, 1983). The NSCLC histologies include squamous cell, adenocarinoma, and large cell and share the properties of poor response to chemotherapy, but frequently complete response to surgical resection at an early stage. In contrast, SCLC tends to metastasize early precluding surgical resection, but has a high initial response rate to combination chemotherapy. Therefore, major treatment decisions hinge upon the distinction between SCLC and NSCLC (Minna et al., 1982), so considerable interest has been focused on developing reagents which would distinguish pathologically between the two forms (Gazdar, 1983).
Administration of Nonsteroidal Anti-inflammatory Agents in Patients With Rheumatoid Arthritis (1983)

We have previously reported that nonsteroidal anti-inflammatory agents (NSAIAs) stimulate cellular immune responses and inhibit production of IgM rheumatoid factor in cultures of lymphocytes from patients with rheumatoid arthritis. We had 20 patients with rheumatoid arthritis stop taking NSAIAs for two weeks and then take piroxicam, a new NSAIA, for an additional ten weeks to assess the in vivo effects of NSAIAs on cellular immunity and rheumatoid factor levels. In each case, serum rheumatoid factor levels rose and phytohemagglutinin response fell when placebo was substituted for NSAIAs. Piroxicam administration was associated with a fall in rheumatoid factor levels to approximately 62% of the baseline level and with an increase in phytohemagglutinin response. The action of NSAIAs in rheumatoid arthritis may be mediated to a degree by partial correction of the disordered immunoregulation in this disease. (<i>JAMA</i>1983;250:2485-2488)
Highly stable aprotic ionic-liquid doped anhydrous proton-conducting polymer electrolyte membrane for high-temperature applications (2011)

Protic ionic-liquid (IL) based polymer electrolyte membranes (PEMs) have been reported for high-temperature fuel cell applications under anhydrous condition. Herein, we report aprotic IL (1-ethyl-3-methylimidazolium ethyl sulfate (EMIES)) and sulfonated poly(ether ether ketone) (SPEEK) based PEMs for fuel cell application under anhydrous condition. Liberated protons from –SO3H groups (SPEEK) due to ionic interaction with EMIES, were responsible for high conductivity under anhydrous conditions. High ionic interaction between the EMIES and SPEEK led to homogeneous mixing. Prepared SPEEK–IL-70 PEM exhibited 0.57 mS cm−1 conductivity (conductivity of EMIES: 3.445 mS cm−1 at room temperature), which was dramatically increased to 18.94 mS cm−1 at 150 °C under anhydrous condition. This enhancement in conductivity was explained due to the well-connected proton conducting channels formed in the polymer matrix because of good miscibility and interaction with EMIES. High stability and good conductivity of SPEEK–IL composite membranes demonstrated their potential application for high-temperature applications.
Comparison of the effects of a conventional heat treatment between cast and selective laser melted IN939 alloy (2016)

Additive manufacturing (AM) is a process where, as the name suggests, material is added during production, in contrast to techniques such as machining, where material is removed. With metals, AM processes involve localised melting of a powder or wire in specific locations to produce a part, layer by layer. AM techniques have recently been applied to the repair of gas turbine blades. These components are often produced from nickel-based superalloys, a group of materials which possess excellent mechanical properties at high temperatures. However, although the microstructural and mechanical property evolution during the high temperature exposure of conventionally produced superalloy materials is reasonably well understood, the effects of prolonged high temperature exposure on AM material are less well known.\nThis research is concerned with the microstructures of components produced using AM techniques and an examination of the effect of subsequent high temperature exposures. In particular, the paper will focus on the differences between cast and SLM IN939 as a function of heat treatment and subsequent ageing, including differences in grain structure and precipitate size, distribution and morphology, quantified using advanced electron microscopy techniques.
Effects of maintaining solstice light and temperature on reproductive activity, coat growth, plasma prolactin and melatonin in goats (1999)

Interactive effects of light and temperature on aspects of seasonality were studied in female British Saanen dairy goats. Four groups of adult non-pregnant non-lactating goats (n = 5) were housed under the following conditions: controls (July-June): natural photoperiod and temperature; group 1 (July-December): long days (16 h light: 8 h dark) and natural temperature; group 2 (July-December): long days and average summer temperature (17.6 degrees C); group 3 (December-June): short days (8 h light: 16 h dark) and winter temperature (8.4 degrees C). Plasma prolactin and progesterone were measured once a week, circadian changes in prolactin and melatonin were determined in December and May, and coat development was assessed. Seasonal variation in prolactin was influenced by manipulation of both daylength and temperature. In group 1, prolactin concentrations decreased as the environmental temperature decreased, despite maintenance of long days. When light and temperature were maintained under summer (group 2) and winter (group 3) conditions, prolactin remained relatively constant, although at different high and low set points, respectively, but with indications of a seasonal rhythm. An asymptotic relationship between prolactin and temperature was maintained under all daylengths. The circadian pattern of melatonin was related to daylength and was not influenced significantly by temperature. Onset of oestrus was unaltered. In group 3 (maintained winter solstice light and temperature), anoestrus was delayed (P < 0.05) from a median control date of 17 March to a median date of 28 April. Winter coat development was delayed in group 1; group 2 showed premature moulting of the winter coat; and in group 3, development of the summer coat was delayed. The results imply that temperature modifies the influence of daylength on prolactin secretion and hair follicle growth by mechanisms that do not involve melatonin.
Effect of Hypoxia Preconditioned Adipose-Derived Mesenchymal Stem Cell Conditioned Medium on Cerulein-Induced Acute Pancreatitis in Mice (2020)

<i><b>Purpose:</b></i> Acute pancreatitis (AP) is an inflammatory disorder distinguished by tissue injury and inflammation of the pancreas. Using paracrine potential of mesenchymal stem cells (MSCs) provides a useful clinical approach in treating inflammatory diseases. We investigated the therapeutic effects of adipose-derived MSC conditioned medium (CM) and hypoxia preconditioned adipose-derived MSC conditioned medium (HCM) in cerulein-induced AP in mice. <i><b>Methods:</b></i> AP was induced in C57BL/6 mice by intraperitoneal injection of cerulein (75 μg/ kg/h × 7 times). One hour following the last injection of cerulein, mice were treated with intraperitoneal injection of CM and HCM (500 µL/mice/30 min × 3 times). Twelve hours following the treatment, serum levels of amylase and lipase were measured. In addition, pancreas pathological changes, immunohistochemical examinations for evaluation of IL-6 expression and pancreatic myeloperoxidase (MPO) enzyme activity were analyzed. <i><b>Results:</b></i> The <i>in vitro</i> results of the morphological, differentiation and immunophenotyping analyses confirmed that hypoxia preconditioned MSCs (HP-MSCs) conserve MSCs characteristics after preconditioning. However, HP-MSCs significantly expressed high mRNA level of hypoxia inducible factor 1-α and higher level of total protein. The <i>in vivo</i> findings of the current study showed that CM and HCM significantly reduced the amylase & lipase activity, the severity of pancreas tissue injury and the expression of IL-6 and MPO enzyme activity compared with the AP group. However, no significant difference between CM and HCM groups was demonstrated. <i><b>Conclusion:</b></i> Use of CM and HCM can attenuate cerulein-induced AP and decrease inflammation in the pancreas tissue in AP mice.
Line relaxation methods for the solution of 2D and 3D compressible flows (1993)

An implicit finite element based algorithm for the compressible Navier-Stokes equations is outlined, and the solution of the resulting equation by a line relaxation on general meshes of triangles or tetrahedra is described. The problem of generating and adapting unstructured meshes for viscous flows is reexamined, and an approach for both 2D and 3D simulations is proposed. An efficient approach appears to be the use of an implicit/explicit procedure, with the implicit treatment being restricted to those regions of the mesh where viscous effects are known to be dominant. Numerical examples demonstrating the computational performance of the proposed techniques are given.
Purification and some properties of cell-bound lipase from Saccharomycopsis lipolytica. (1982)

Two kinds of cell-bound Upases were purified from S. lipolytica with a total recovery of 8%. One was adsorbed and the other not to CM-Sepharose CL-6B at pH 5.0. The method of purification involved chromatography on CM-Sepharose CL-6B, DEAE-Sepharose CL-6B and Sephadex G-100 columns. Sodium dodecylsulfate-polyacrylamide gel electrophoresis of the purified lipases gave a single band. The purified lipases required an activator, such as oleic acid for hydrolysis of triglycerides. The lipases hydrolyzed tricaprylin at the largest initial rate and the optimum pH for hydrolysis of olive oil was about 8.0 under the experimental conditions. They were stable for 20 min below 37°C and in a pH range from 4.5 to 8.0 for 22hr at 5°C. The molecular weight of Lipase I and II was estimated to be 39, 000 and 44, 000, respectively, and both lipases were a monomeric enzyme.
First Principles Predictions of Gun Tube Erosion Chemistry and Possible Protective Coatings (2002)

Abstract : Increasing the service lifetime of military machinery will improve logistics in the field (less down-time due to maintenance or replacement) and will free up resources for other pressing needs. To this end, the Army has a vested interest in enhancing the lifetime of gun barrels, which are limited currently by erosion of the steel from which the gun barrels are made. However, it is exceedingly difficult to determine experimentally in situ the mechanisms of erosion. Therefore, computer simulations can help elucidate those mechanisms and in ultimately extending the lifetime of gun barrels by discovering new ways to inhibit erosion.
Scientific Data Management Challenges in High-Performance Visual Data Analysis (2009)

Visualization is a highly data intensive science: visualization algorithms take as input vast amounts of data produced by simulations or experiments, and then transform that data into imagery.It turns out, as we shall explore in this chapter, that visualization reveals a somewhat different view of scientific data management challenges than are examined elsewhere 1 2Scientific Data Management Challenges in High Performance Visual Data Analysis in this book.For example, a data ordering and storage layout that works well for saving data from memory to disk may not be the best thing for subsequent visual data analysis algorithms.This chapter will present four broad topic areas under this general rubric: (1) a view of SDM-related issues from the perspective of implementing a production-quality, parallel capable visual data analysis infrastructure; (2) novel data storage formats for multi-resolution, streaming data movement, access and use by post-processing tools; (3) data models, formats and APIs for performing efficient I/O for both simulations and post-processing tools, discussion of issues and previous work in this space; (4) how combining stateof-the-art techniques from scientific data management and visualization enables visual data analysis of truly massive datasets.
Mechanical properties of highly filled latex-based polystyrene/laponite nanocomposites (2009)

International audience
First Migration: Up and Running! (2016)

Editorial Vorwort 1.BEITRÃGE Die VideobestÃ¤nde des Phonogrammarchis Hedwig KÃ¶b & Katharina Thenius-Wilscher Firts Migration: Up and Running! Franz Pavuza Der indische RevolutionÃ¤r Har Dayal und seine Tonaufnahmen von 1918 im Phonogrammarchiv der Ãsterreichischen Akademie der Wissenschaften Ulla Remmer Afrikanische Geschichte hÃ¶ren? Gedanken zur Quellenkritik des Tons Clemens GÃ¼tl Mapping "Portuguese music": the Armando LeÃ§a Collection (1939/40) Maria do Rosario Pestana 2. FELDFORSCHUNGS- UND PROJEKTBERICHT Quellenkritische Anmerkungen zur Feldforschung Ã¼ber griechisch-orthodoxe OsterbrÃ¤uche (Olympos/Karpathos, 2.- 7. Mai 2013) Rudolf M. Brandl &Bernhard Graf AbschluÃbericht des Projektes "European Acoustic Heritage" JÃ¼rgen SchÃ¶pf 3. REZENSIONEN Britta Lange.2013. Die Wiener Forschungen an Kriegsgefangenen 1915-1918: Anthropologische und ethnografische Verfahren im Lager Wien: VÃAW. Gabriele FrÃ¶schl Marc Sinan.2013. Hasretim - Journey to Anatolia. CD/DVD. (ECM 2330/31),. Munich: ECM Records. JÃ¼rgen SchÃ¶pf & Meri KytÃ¶ TÃ¤tigkeitsbericht des Phonogrammarchivs fÃ¼r das Jahr 2013
An automated online monitor of control system performance (1997)

A novel method for automated, online, goodness of control evaluation is developed and experimentally demonstrated. The method uses a computationally simple, robust statistic and compares it to the distribution of that statistic from a control period previously judged "good" by the process owner.
Sexual Differences in Regulation of Prolactin Secretion by Two Hypothalamic Areas* (1982)

Two sexually dimorphic areas of the hypothalamus, the dorsomedial-ventromedial nuclei (DMN-VMN) and the medial preoptic area (MPOA) have been shown to be involved in the regulation of rhythmic PRL secretion induced by cervical stimulation. The present study investigated the sexually specific roles played by the DMN-VMN and the MPOA in controlling PRL release. Four groups of rats were used in this study: adult ovariectomized females (OVX-females), adult castrated males (AC-males), females given testosterone propionate at birth (TP-females), and males castrated neonatally (NCmales). In a test of hypothalamic differentiation, OVX-females and NC-males could secrete LH surges after a steroid challenge whereas AC-males and TP-females could not. Electrical stimulation was applied to the DMN-VMN of animals from all four groups. The animals were then sampled on day 2 after stimulation at times appropriate for detection of nocturnal (N) and diurnal (D) surges of PRL similar to those induced by mating in females. OVX-females produced both N and D surges of PRL. No other groups released PRL surges. Even after placement of progesterone implants sc 1 day before DMN-VMN stimulation, AC-males and TP-females remained unresponsive. However, NC-males bearing progesterone implants did secrete N but not D PRL surges after stimulation. Bilateral MPOA lesions were also placed in animals from the four groups. With no progesterone implants only the OVX-females released N PRL surges. With the steroid implants, the MPOA lesions induced small N and D surges in AC-males, as well as elevated PRL levels at all times in TP-females and NC-males. Also, cervical stimulation, a more physiological stimulus, could not initiate PRL surges in TP-females or TP-females with progesterone implants. These results suggest that both the DMN-VMN and the MPOA have sexually differentiated functions in the control of PRL release that can only be partially reversed by manipulation of the neonatal steroid environment.
Plasma Endothelin Levels in Healthy Children (1991)

We measured plasma endothelin-1-like immunoreactivity (ET-1-LI) levels in the peripheral vein of 70 healthy children (37 males and 33 females) aged 5 days to 15 years to establish the normal range in children, and compared them with those in 11 normal adults (age, mean +/- SD; 29.5 +/- 5.7 years, 6 males and 5 females). Plasma ET-1-LI levels (pg/ml, mean +/- SD) in children of each age group and adults were as follows: children younger than 1 month = 23.4 +/- 3.9 (n = 10), 1-3 months = 25.0 +/- 6.1 (n = 8), 3-6 months = 17.0 +/- 1.4 (n = 8), 6 months to 1 year = 14.0 +/- 1.7 (n = 13), 1-5 years = 13.8 +/- 2.6 (n = 11), 5-10 years = 13.6 +/- 1.6 (n = 10), 10-15 years = 12.9 +/- 2.2 (n = 10), and adults = 13.2 +/- 2.4 (n = 11). There was no significant difference in plasma ET-1-LI levels between males and females in each age group. Plasma ET-1-LI levels in children younger than 3 months were significantly (p less than 0.01) higher than those in older children or adults. After 3 months of age, plasma ET-1-LI levels were nearly constant at all ages. This is the first report to establish the normal range of plasma ET-1-LI levels in children.
Dynamic Imaging of Allogeneic Mesenchymal Stem Cells Trafficking to Myocardial Infarction (2005)

Noninvasive radionuclide imaging is well suited to dynamically track the biodistribution and trafficking of mesenchymal stem cells to both target and nontarget organs.
Teratocarcinomas and human embryology: Pluripotent human EC cell lines (1998)

The histogenesis of germ cell tumours (GCT) reflects the normal processes of gametogenesis, fertilisation and subsequent embryonic cell differentiation. Understanding the mechanisms that control the differentiation of embryonal carcinoma (EC) cells into a variety of embryonic and extraembryonic cell types is pertinent to understanding the progression of GCT. EC cells also provide a tool for analysing the mechanisms that control differentiation during embryonic development, and particularly the mechanisms that control differentiation along alternative cell line, NTERA2, into neurones and other cell types in response to agents such as retinoic acid, HMBA and the bone morphogenetic proteins. We have also compared the pluripotent NTERA2 EC cells with other human EC cell lines that exhibit a much reduced capacity for cell differentiation. A variety of genes are activated during NTERA2 differentiation. In particular we have identified a novel human member of the wnt family. This wnt gene is activated following retinoic acid induction of differentiation but is later down-regulated as the cells mature into neurones and other cell types. We have also observed expression of genes belonging to the Frizzled family, which is likely to include genes encoding receptors for the wnt gene products. Thus in the NTERA2 system, genes pertinent to regulating cell differentiation during embryonic development are activated and appear to play a role in modulating how these pluripotent human EC cells differentiate.