gebhart/patrepeval huggingface dataset:
Unraveling gelation kinetics, arrested dynamics and relaxation phenomena in filamentous colloids by photon correlation imaging (2022)

The fundamental understanding of the gelation kinetics, stress relaxation and temporal evolution in colloidal filamentous gels is central to many aspects of soft and biological matter, yet a complete description of the inherent complex dynamics of these systems is still missing. By means of photon correlation imaging (PCI), we studied the gelation of amyloid fibril solutions, chosen as a model filamentous colloid with immediate significance to biology and nanotechnology, upon passage of ions through a semi-permeable membrane. We observed a linear-in-time evolution of the gelation front and rich rearrangement dynamics of the gels, the magnitude and the spatial propagation of which depend on how effectively electrostatic interactions are screened by different ionic strengths. Our analysis confirms the pivotal role of salt concentration in tuning the properties of amyloid gels, and suggests potential routes for explaining the physical mechanisms behind the linear advance of the salt ions.
Regulating actin dynamics in neuronal growth cones by ADF/cofilin and Rho family GTPases (2000)

Growth cone motility and navigation in response to extracellular signals are regulated by actin dynamics. To better understand actin involvement in these processes we determined how and in what form actin reaches growth cones, and once there, how actin assembly is regulated. A continuous supply of actin is maintained at the axon tip by slow transport, the mobile component consisting of an unassembled form of actin. Actin is co-transported with actin-binding proteins, including ADF and cofilin, structurally related proteins essential for rapid turnover of actin filaments in vivo. ADF and cofilin activity is regulated through phosphorylation by LIM kinases, downstream effectors of the Rho family of GTPases, Cdc42, Rac and Rho. Attractive and repulsive extracellular guidance cues might locally alter actin dynamics by binding specific GTPase-linked receptors, activating LIM kinases, and subsequently modulating the activity of ADF/cofilin. ADF is enriched in growth cones and is required for neurite outgrowth. In addition, signals that influence growth cone behavior alter ADF/cofilin phosphorylation, and overexpression of ADF enhances neurite outgrowth. Growth promoting effects of laminin are mimicked by expression of constitutively active Cdc42 and blocked by expression of the dominant negative Cdc42. Repulsive effects of myelin and sema3D on growth cones are blocked by expression of constitutively active Rac1 and dominant negative Rac1, respectively. Thus a series of complex pathways must exist for regulating effectors of actin dynamics. The bifurcating nature of the ADF/cofilin phosphorylation pathway may provide the integration necessary for this complex regulation.
The efficiency of adiabatic inversion for perfusion imaging by arterial spin labeling (1997)

Velocity-driven adiabatic inversion is an attractive method for labeling arterial blood spins for quantitative perfusion imaging. To quantify perfusion and to optimize experimental parameters, an accurate estimate of labeling efficiency is required. We present theoretical and numerical methods to calculate the labeling efficiency over a wide range of experimental and physiologic parameters. The results are compared to experimental measurements in vivo. Inversion efficiency was found to be higher than previously assumed and relatively insensitive to flow velocity and the amplitude of the RF irradiation used for inversion. Assuming laminar flow, labeling efficiencies of greater than 90% are easily obtainable over a broad range of flow velocities. For applications where RF power deposition is a limiting factor such as at high field strengths, labeling efficiency can be maintained by reducing the labeling gradient. These results further illustrate the capability of adiabatic inversion to effectively label flowing blood.
Fusion of lens-free microscopy and mobile-phone microscopy images for high-color-accuracy and high-resolution pathology imaging (2017)

Digital pathology and telepathology require imaging tools with high-throughput, high-resolution and accurate color reproduction. Lens-free on-chip microscopy based on digital in-line holography is a promising technique towards these needs, as it offers a wide field of view (FOV &gt;20 mm<sup>2</sup>) and high resolution with a compact, low-cost and portable setup. Color imaging has been previously demonstrated by combining reconstructed images at three discrete wavelengths in the red, green and blue parts of the visible spectrum, i.e., the RGB combination method. However, this RGB combination method is subject to color distortions. To improve the color performance of lens-free microscopy for pathology imaging, here we present a wavelet-based color fusion imaging framework, termed “digital color fusion microscopy” (DCFM), which digitally fuses together a grayscale lens-free microscope image taken at a single wavelength and a low-resolution and low-magnification color-calibrated image taken by a lens-based microscope, which can simply be a mobile phone based cost-effective microscope. We show that the imaging results of an H&amp;E stained breast cancer tissue slide with the DCFM technique come very close to a color-calibrated microscope using a 40x objective lens with 0.75 NA. Quantitative comparison showed 2-fold reduction in the mean color distance using the DCFM method compared to the RGB combination method, while also preserving the high-resolution features of the lens-free microscope. Due to the cost-effective and field-portable nature of both lens-free and mobile-phone microscopy techniques, their combination through the DCFM framework could be useful for digital pathology and telepathology applications, in low-resource and point-of-care settings.
Catalase vs Peroxidase Activity of a Manganese(II) Compound: Identification of a Mn(III)−(μ-O)2−Mn(IV) Reaction Intermediate by Electrospray Ionization Mass Spectrometry and Electron Paramagnetic Resonance Spectroscopy (2009)

Herein, we report reactivity studies of the mononuclear water-soluble complex [Mn(II)(HPClNOL)(eta(1)-NO(3))(eta(2)-NO(3))] 1, where HPClNOL = 1-(bis-pyridin-2-ylmethyl-amino)-3-chloropropan-2-ol, toward peroxides (H(2)O(2) and tert-butylhydroperoxide). Both the catalase (in aqueous solution) and peroxidase (in CH(3)CN) activities of 1 were evaluated using a range of techniques including electronic absorption spectroscopy, volumetry (kinetic studies), pH monitoring during H(2)O(2) disproportionation, electron paramagnetic resonance (EPR), electrospray ionization mass spectrometry in the positive ion mode [ESI(+)-MS], and gas chromatography (GC). Electrochemical studies showed that 1 can be oxidized to Mn(III) and Mn(IV). The catalase-like activity of 1 was evaluated with and without pH control. The results show that the pH decreases when the reaction is performed in unbuffered media. Furthermore, the activity of 1 is greater in buffered than in unbuffered media, demonstrating that pH influences the activity of 1 toward H(2)O(2). For the reaction of 1 with H(2)O(2), EPR and ESI(+)-MS have led to the identification of the intermediate [Mn(III)Mn(IV)(mu-O)(2)(PClNOL)(2)](+). The peroxidase activity of 1 was also evaluated by monitoring cyclohexane oxidation, using H(2)O(2) or tert-butylhydroperoxide as the terminal oxidants. Low yields (<7%) were obtained for H(2)O(2), probably because it competes with 1 for the catalase-like activity. In contrast, using tert-butylhydroperoxide, up to 29% of cyclohexane conversion was obtained. A mechanistic model for the catalase activity of 1 that incorporates the observed lag phase in O(2) production, the pH variation, and the formation of a Mn(III)-(mu-O)(2)-Mn(IV) intermediate is proposed.
Central acoustic tract in an echolocating bat: An extralemniscal auditory pathway to the thalamus (1989)

To determine the sources and targets of auditory pathways that bypass the inferior colliculus in the mustache bat, we injected WGA-HRP in the medial geniculate body and related auditory nuclei of the thalamus as well as in the lower brainstem. We used electrophysiological methods to verify that the injection electrode was in an area responsive to sound. The only thalamic injections that produced retrograde transport to cells in auditory nuclei caudal to the inferior colliculus were those that included the suprageniculate nucleus. These injections labeled a group of large multipolar cells lying between the ventral nucleus of the lateral lemniscus and the superior olivary complex. Neurons in this cell group have also been shown to project to the deep layers of the superior colliculus in the mustache bat. The pathway revealed by these studies is almost identical to the "central acoustic tract" in which fibers course medial to the lateral lemniscus and bypass the inferior colliculus to reach the deep superior colliculus and the suprageniculate nucleus.
Haemodynamic and Hormonal Responses to Cardiac Pacing in Humans: Influence of Different Stimulation Sequences and Rates (1995)

1. To examine the effects of rate and pressure on release of vasoactive hormones, 10 healthy subjects were examined. 2. A standardized pacing protocol was used to achieve different haemodynamic responses at two predetermined heart rates. Haemodynamic variables, and plasma concentrations of atrial natriuretic peptide, arginine vasopressin, adrenaline and noradrenaline were measured. 3. Right atrioventricular pacing at a rate of 150 impulses/min resulted in disparate responses in right atrial pressure (slight decrease) and pulmonary capillary wedge pressure (increase). Change in arterial plasma concentration of atrial natriuretic peptide correlated to change in pulmonary capillary wedge pressure, and change in arterial plasma concentration of noradrenaline correlated to change in total systemic vascular resistance, whereas concentrations of adrenaline and arginine vasopressin did not alter significantly during the stimulation periods. A significant influence of rate in addition to the pressure related influence on plasma concentration of atrial natriuretic peptide was found. In contrast, an increase in rate in the absence of an increase in atrial pressures did not raise the plasma concentration of atrial natriuretic peptide. There was no significant relationship between change in atrial natriuretic peptide and noradrenaline. 4. These data support the concept of a rate dependence of atrial natriuretic peptide release in man. Increased atrial pressure and thus presumed atrial stretch seems to be a prerequisite for increased plasma concentration of atrial natriuretic peptide. In addition, these results highlight the importance of monitoring both left and right atrial pressure in clinical investigations assessing modulation of atrial natriuretic peptide release.
Quercetin reduces hydroxyurea induced cytotoxicity in immortalized mouse aortic endothelial cells (2017)

These results suggest that quercetin may be effective against vascular endothelial cell damage for iMAECs <i>in vitro</i>. In particular, it shows promise in preventing HU-induced cytotoxicity, surprisingly found from these results. This latter finding is important, and should be given more consideration, since HU is the only FDA-approved drug for treating sickle cell patients, and its use is rapidly increasing.
Multifunctional structural lithium-ion battery for electric vehicles (2016)

An innovative concept for a multifunctional structural battery using lithium-ion battery materials as load bearing elements in a sandwich panel construction has been demonstrated. The structural battery prototype has exhibited an initial capacity of 17.85 Ah, an energy density of 248 Wh L −1 , a specific energy of 102 Wh kg −1 , and a capacity retention of 85.8% after 190 charge–discharge cycles at ~ C/3 rate and eight mechanical loading cycles (upto 1060 N). The mechanical stiffness in three-point bend tests follows expectations based on sandwich beam theory, proving that the battery materials are sharing in the load-carrying function of the sandwich panel. While areas for improvement of the fabrication and performance of the prototype still exist, the results of the current investigation demonstrate the promising potential of the proposed structural battery concept for the efficient use of space and mass in an electric vehicle.
Redox chemistry of the homoleptic aryl Os(2-MeC6H4)4: synthesis and characterization of the first osmium(V) organometallic [Os(2-MeC6H4)4][CF3SO3] (1988)

J. Arnold, G. Wilkinson, B. Hussain and M. B. Hursthouse, J. Chem. Soc., Chem. Commun., 1988, 1349 DOI: 10.1039/C39880001349
Dynamic Species Distribution Models in the Marine Realm: Predicting Year-Round Habitat Suitability of Baleen Whales in the Southern Ocean (2021)

Species distribution models (SDMs) relate species information to environmental conditions to predict potential species distributions. The majority of SDMs are static, relating species presence information to long-term average environmental conditions. The resulting temporal mismatch between species information and environmental conditions can increase model inference’s uncertainty. For SDMs to capture the dynamic species-environment relationships and predict near-real-time habitat suitability, species information needs to be spatiotemporally matched with environmental conditions contemporaneous to the species’ presence (dynamic SDMs). Implementing dynamic SDMs in the marine realm is highly challenging, particularly due to species and environmental data paucity and spatiotemporally biases. Here, we implemented presence-only dynamic SDMs for four migratory baleen whale species in the Southern Ocean (SO): Antarctic minke, Antarctic blue, fin, and humpback whales. Sightings were spatiotemporally matched with their respective daily environmental predictors. Background information was sampled daily to describe the dynamic environmental conditions in the highly dynamic SO. We corrected for spatial sampling bias by sampling background information respective to the seasonal research efforts. Independent model evaluation was performed on spatial and temporal cross-validation. We predicted the circumantarctic year-round habitat suitability of each species. Daily predictions were also summarized into bi-weekly and monthly habitat suitability. We identified important predictors and species suitability responses to environmental changes. Our results support the propitious use of dynamic SDMs to fill species information gaps and improve conservation planning strategies. Near-real-time predictions can be used for dynamic ocean management, e.g., to examine the overlap between habitat suitability and human activities. Nevertheless, the inevitable spatiotemporal biases in sighting data from the SO call for the need for improving sampling effort in the SO and using alternative data sources (e.g., passive acoustic monitoring) in future SDMs. We further discuss challenges of calibrating dynamic SDMs on baleen whale species in the SO, with a particular focus on spatiotemporal sampling bias issues and how background information should be sampled in presence-only dynamic SDMs. We also highlight the need to integrate visual and acoustic data in future SDMs on baleen whales for better coverage of environmental conditions suitable for the species and avoid constraints of using either data type alone.
Awareness and Practice of Prenatal and Obstetric Care among Mothers in Ekpoma, Edo-Nigeria (2014)

A survey of 320 mothers who had carried at least one pregnancy to term was conducted to determine their awareness and utilization of prenatal services and hospital delivery. The study was conducted in Ekpoma, Esan West Local Government Area of Edo State- Nigeria, using interviewer administered questionnaire. The results showed that all the mothers (320; 100%) have heard of prenatal care and majority of the mothers (250; 78.130%) have good knowledge of it. Although majority of the mothers (306; 95.63%) utilized prenatal services during their last pregnancy, only 264 (82.50%) utilized the services of skilled birth attendants during delivery in the following places; public health clinics (14; 5.30%), private clinics (22; 8.33%) and teaching hospital (228; 86.36%). Despite the high degree of prenatal services utilization (95.63%) by the mothers in this study, it is worrisome to observed in this study that 17.50% still utilized the services of untrained birth attendants at home (11.88%) and the services of traditional birth attendants (5.63%). Based on our findings, it is suggest that further studies investigate the determinant of the utilization of hospital delivery or services of skilled birth attendants during delivery in the study area.
Preparation and Hydrolysis of Some Acetals and Esters of D(—)-2,3-Butanediol (1950)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPreparation and Hydrolysis of Some Acetals and Esters of D(—)-2,3-ButanediolH. K. Garner and H. J. LucasCite this: J. Am. Chem. Soc. 1950, 72, 12, 5497–5501Publication Date (Print):December 1, 1950Publication History Published online1 May 2002Published inissue 1 December 1950https://pubs.acs.org/doi/10.1021/ja01168a033https://doi.org/10.1021/ja01168a033research-articleACS PublicationsRequest reuse permissionsArticle Views449Altmetric-Citations43LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The Stepwise Dimensionality Increasing (SDI) Index for High-Dimensional Data (2006)

Journal Article The Stepwise Dimensionality Increasing (SDI) Index for High-Dimensional Data Get access Alexander Thomasian, Alexander Thomasian * Department of Computer Science, New Jersey Institute of TechnologyNewark, NJ 07102, USA *Corresponding author: alexthomasian@gmail.com Search for other works by this author on: Oxford Academic Google Scholar Lijuan Zhang Lijuan Zhang Department of Computer Science, New Jersey Institute of TechnologyNewark, NJ 07102, USA Search for other works by this author on: Oxford Academic Google Scholar The Computer Journal, Volume 49, Issue 5, September 2006, Pages 609–618, https://doi.org/10.1093/comjnl/bxl022 Published: 25 May 2006 Article history Received: 01 April 2005 Revision received: 20 March 2006 Published: 25 May 2006
Peran Shared Leisure Satisfaction dan Conflict Resolution Terhadap Co- Parenting pada Pasangan Dual Earner Di Gereja X (2020)

This study was conducted to determine the role of shared leisure satisfaction and conflict resolution on co-parenting in dual earner couples in church X. The hypothesis in this study is that shared leisure satisfaction and conflict resolution play a significant role in co-parenting. Using quantitative research methods with correlational designs. The subjects in this study were 90 dual earner congregants in Church X in Banyuwangi because a phenomenon that was found to be suitable for the population was obtained by accidental sampling technique. Data analysis using multiple linear regression test showed that shared leisure satisfaction and conflict resolution contribute to co-parenting in dual earner pairs (F = 23,164; p &lt; 0,05), for conflict resolution it plays a role in co-parenting (t = 4,928; p &lt;0,05 ), so also shared leisure satisfaction contributes to co-parenting (t = 4,347; p &lt; 0,05). The total effective contribution of the two variables is 34,7% (R2 = 0,347). The conclusion of this study is that shared leisure satisfaction and conflict resolution play a role in co- parenting in dual earners.
Three-Band White Light-Emitting Diodes Based on Hybridization of Polyfluorene and Colloidal CdSe–ZnS Quantum Dots (2010)

The authors have demonstrated the hybridization of polyfluorene (PFO) polymer light-emitting diodes with CdSe-ZnS core/shell quantum dots (QDs) in different device structures. To achieve white light emission, the green and red QDs have been incorporated into the PFO as the single emissive layer. Furthermore, the whole structures were also optimized to engineer the emission spectra. Accordingly, the incorporation of QDs increased the turn-on voltage from 10 to 23 V in device with the blend ratio of PFO : green QD : red QD being 6 : 1 : 1, while the maximum brightness was dramatically decreased.
Historical Theology (2011)

This chapter contains sections titled: Developments in Practical Theology Historical Theology's Turn to the Practical Congregational Histories Historical Discourse as Ideology and the Turn to Daily Life Historical Theology, Practical Methodology, and Theological Education References
Can the scaling behavior of electric conductivity be used to probe the self-organizational changes in solution with respect to the ionic liquid structure? The case of [C8MIM][NTf2] (2015)

Electrical conductivity of the supercooled ionic liquid [C8MIM][NTf2], determined as a function of temperature and pressure, highlights strong differences in its ionic transport behavior between low and high temperature regions. To date, the crossover effect which is very well known for low molecular van der Waals liquids has been rarely described for classical ionic liquids. This finding highlights that the thermal fluctuations could be dominant mechanisms driving the dramatic slowing down of ion motions near Tg. An alternative way to analyze separately low and high temperature dc-conductivity data using a density scaling approach was then proposed. Based on which a common value of the scaling exponent γ = 2.4 was obtained, indicating that the applied density scaling is insensitive to the crossover effect. By comparing the scaling exponent γ reported herein along with literature data for other ionic liquids, it appears that γ decreases by increasing the alkyl chain length on the 1-alkyl-3-methylimidazolium-based ionic liquids. This observation may be related to changes in the interaction between ions in solution driven by an increase in the van der Waals type interaction by increasing the alkyl chain length on the cation. This effect may be related to changes in the ionic liquid nanostructural organization with the alkyl chain length on the cation as previously reported in the literature based on molecular dynamic simulations. In other words, the calculated scaling exponent γ may be then used as a key parameter to probe the interaction and/or self-organizational changes in solution with respect to the ionic liquid structure.