gebhart/patrepeval huggingface dataset:
Sobre los carrascales ermomediterráneos valencianos (1982)

A study of the Valencian thermomediterranean holm oak woodlands is presented, relating them to their substitution stages. Three new associations are described: Rubio longifoliae-Quercerum rotundifoliae
(Oleo-Quercion rotundafolio-suberis); Genisto hispanicae-Anthyllidetum onobrychioidis (Rosmarino-Ericion) and Lobulario maruimae-Euphorbietum pinece (Diplotaxion erucoidis).
Conceptual Design Of Pulse Generators For Driving Recirculating Induction Accelerators (1991)

The objective of this technology development program was to develop repetitive pulse generator technology for driving the Spiral Line Inductance Accelerator (SLIA) at a repetition rate of 10 MHz with pulse characteristics of 300 kV, 12 -15 kA in a 30 nanosecond wide pulse, plus a 70 ns core reset pulse. These are stiff requirements for conventional pulsed power switching technologies. At Tetra Corporation we have pursued an alternate approach to the pulse generator. Two basic approaches to producing a pulse shape with the correct shape for the SLIA application were developed. Experimental results with low voltage version of the pulse generator demonstrated the performance characteristics in hardware.
Identification of an HLA‐A null allele, HLA‐A*33:129N (2018)

HLA-A*33:129N has a single nucleotide insertion compared with its closest allele HLA-A*33:01:01 at codon 186.
Translation of messenger ribonucleic acid from isolated pancreatic islets and human insulinomas. (1975)

RNA preparations from isolated rat pancreatic islets and from human insulinomas were injected into oocytes of Xenopus laevis which were then incubated with [3H]leucine. Acid-ethanol extracts of the oocytes were immunoprecipitated with anti-insulin serum using the double antibody technique. Sodium dodecyl sulfate disc gel electrophoresis of the immunoprecipitates showed the presence of an insulin-displaceable immunoreactive material with a molecular weight of about 18,000 in extracts from oocytes injected with RNA of 9-11 S. This immunoreactive product was not detected in extracts from oocytes injected with buffer or 4-8S RNA or RNA heavier than 11 S. These observations suggest the involvement of a precursor larger than proinsulin in the biosynthesis of insulin.
Modeling and Validation of Fluid Structure Interactions in Passive Micro Valves (1998)

This paper reports the modeling of the stationary flow-structure interaction of different types of micro check valves. Mathematical indirect, domain coupled and decoupled, finite element models as well as analytical approximations are made. The obtained simulation results are validated by performed measurements on fabricated micro valves. Simple analytical formulas are derived. These can be used for micro fluid handing component design purposes as well as for input for numerical lumped element system simulation programs.
Self-stabilizing distributed file system (2005)

A self-stabilizing distributed file systems is presented. The system constructs and maintains a spanning tree for each file volume. The spanning tree consists of the servers that have volume replicas and caches for the specific file volume. The spanning trees are constructed and maintained by self-stabilizing distributed algorithms. A self-stabilizing synchronizer enforces file system semantics and consistent replications. File system updates use the tree to implement file read and write operations. A prototype of the system based on the Linux operating system has been implemented.
Exact cuts in networks (1989)

Abstract An exact cut in a source‐sink network is a set of arcs which interesects each source‐sink path in exactly one arc. This paper investigates the problem of finding a maximum weight exact cut in a network. The problem is shown to be polynomially equivalent to that of determining the relevant arcs (arcs on at least one source‐sink path) in the network and is NP‐hard for general directed networks. There are, however, several important classes of network—including undirected networks—for which polynominal time algorithms do exist to solve the maximum weight exact cut problem.
Suppression of the c-erbB-2 gene product decreases transformation abilities but not the proliferation and secretion of proteases of SK-OV-3 ovarian cancer cells (1999)

The overexpression of the c-erbB-2 oncogene product has been reported in approximately 20-30% of human ovarian cancers and has been correlated with a poor prognosis in ovarian cancer patients. To investigate the function of p185(c-erbB-2) in human ovarian cancer cells, a c-erbB-2-specific single-chain antibody (scFv-5R) was expressed in the c-erbB-2-overexpressing SK-OV-3 cell line using a retroviral expression vector. Eight individual clones expressing the single-chain antibody were isolated. These clones have a prominent retention of the cell surface p185(c-erbB-2). In this study we compared the proliferation rate, the anchorage-independent growth, the secretion of matrix metalloproteases and of the urokinase-type plasminogen activator. The clones expressing the c-erbB-2 single-chain antibody, the control cells harbouring the empty vector and the parental SK-OV-3 cells they all had similar proliferation rates in the presence of 10% serum and secreted similar amounts of matrix metalloproteases and of the urokinase-type plasminogen activator. However, the expression of the c-erbB-2 oncogene product offers a strong growth advantage under serum-reduced conditions with 1% serum. In contrast to the parental SK-OV-3 and empty vector control cells, the scFv-5R-expressing clones were not able to grow anchorage-independently. These findings suggest that c-erbB-2 enhances transformation abilities of SK-OV-3 ovarian cancer cells without affecting the secretion of proteases and the proliferation of SK-OV-3 ovarian cancer cells in the presence of high concentrations of serum.
Performance characteristics of a second generation micro crystal element (MiCE2) detector (2005)

This work reports on performance characteristics of a second generation micro crystal element (MiCE2) detector for a dedicated PET system to image mice. Our MiCE2 detector consists of a 22/spl times/22, array of 0.8/spl times/0.8/spl times/6 mm mixed lutetium silicate (MLS) crystals. Five sides of the crystals are polished with one 0.80.8 mm face left unpolished. The crystals are placed within a grid made of a highly reflective polymer film material. The grid optically isolates the crystals and also functions as a reflective wrap. The detector unit is directly coupled to a 6+6 cross-anode position sensitive PMT. The crystal of interaction is determined using simple Anger style logic. Crystal maps have been created for a 22/spl times/22 crystal array. All 484 crystals are visualized in the full detector module's crystal map. The average peak to valley ratio between neighboring crystals was 6.4. There was greater than a factor of two difference between the photopeak energy channel for high versus low light collection efficiency crystals. The energy resolution for individual crystals varied between 14% and 23%. Partial detector arrays (e.g., 22/spl times/4) using 0.8/spl times/0.8/spl times/10 mm crystals with an etched surface finish have also been built and decoded. A miniature line source phantom consisting of five 1 mm diameter lines with 2 mm center-to-center spacing has been imaged using two partial MiCE2 detectors. All lines are distinguished and. the average peak to valley ratio between lines is 2.7.
Nanodroplets deposited in microarrays by femtosecond Ti:sapphire laser-induced forward transfer (2006)

The authors present the deposition of nanoscale droplets of Cr using femtosecond Ti:sapphire laser-induced forward transfer. Deposits around 300nm in diameter, significantly smaller than any previously reported, are obtained from a 30nm thick source film. Deposit size, morphology, and adhesion to a receiver substrate as functions of applied laser fluence are investigated. The authors show that deposits can be obtained from previously irradiated areas of the source material film with negligible loss of deposition quality, allowing subspot size period microarrays to be produced without the need to move the source film.
Developmental stage-specific biphasic roles of Wnt/β-catenin signaling in cardiomyogenesis and hematopoiesis (2006)

Although Wingless (Wg)/Wnt signaling has been implicated in heart development of multiple organisms, conflicting results have been reported regarding the role of Wnt/beta-catenin pathway in cardiac myogenesis: Wg/armadillo signaling promotes heart development in Drosophila, whereas activation of Wnt/beta-catenin signaling inhibits heart formation in avians and amphibians. Using an in vitro system of mouse ES cell differentiation into cardiomyocytes, we show here that Wnt/beta-catenin signaling exhibits developmental stage-specific, biphasic, and antagonistic effects on cardiomyogenesis and hematopoiesis/vasculogenesis. Activation of the Wnt/beta-catenin pathway in the early phase during embryoid body (EB) formation enhances ES cell differentiation into cardiomyocytes while suppressing the differentiation into hematopoietic and vascular cell lineages. In contrast, activation of Wnt/beta-catenin signaling in the late phase after EB formation inhibits cardiomyocyte differentiation and enhances the expression of hematopoietic/vascular marker genes through suppression of bone morphogenetic protein signaling. Thus, Wnt/beta-catenin signaling exhibits biphasic and antagonistic effects on cardiomyogenesis and hematopoiesis/vasculogenesis, depending on the stage of development.
Differential Activation of Human Monocyte-Derived and Plasmacytoid Dendritic Cells by West Nile Virus Generated in Different Host Cells (2007)

Dendritic cells (DCs) play a central role in innate immunity and antiviral responses. In this study, we investigated the production of alpha interferon (IFN-alpha) and inducible chemokines by human monocyte-derived dendritic cells (mDCs) and plasmacytoid dendritic cells (pDCs) infected with West Nile virus (WNV), an emergent pathogen whose infection can lead to severe cases of encephalitis in the elderly, children, and immunocompromised individuals. Our experiments demonstrated that WNV grown in mammalian cells (WNV(Vero)) was a potent inducer of IFN-alpha secretion in pDCs and, to a lesser degree, in mDCs. The ability of WNV(Vero) to induce IFN-alpha in pDCs did not require viral replication and was prevented by the treatment of cells with bafilomycin A1 and chloroquine, suggesting that it was dependent on endosomal Toll-like receptor recognition. On the other hand, IFN-alpha production in mDCs required viral replication and was associated with the nuclear translocation of IRF3 and viral antigen expression. Strikingly, pDCs failed to produce IFN-alpha when stimulated with WNV grown in mosquito cells (WNV(C7/10)), while mDCs responded similarly to WNV(Vero) or WNV(C7/10). Moreover, the IFN-dependent chemokine IP-10 was produced in substantial amounts by pDCs in response to WNV(Vero) but not WNV(C7/10), while interleukin-8 was produced in greater amounts by mDCs infected with WNV(C7/10) than in those infected with WNV(Vero). These findings suggest that cell-specific mechanisms of WNV recognition leading to the production of type I IFN and inflammatory chemokines by DCs may contribute to both the innate immune response and disease pathogenesis in human infections.
Thrombotic microangiopathy in renal allografts (2014)

TMA is a serious complication of renal transplantation, usually with poor outcome. However, with improving understanding of underlying pathogeneses, more effective disease-specific therapeutic interventions can be designed. Appropriate treatment depends on the correct diagnosis, which relies primarily on renal allograft biopsy. Standardization of pathologic criteria and introduction of new molecular testing methods in renal biopsy specimens hopefully will improve diagnostic accuracy.
Inhibition of Bcr Serine Kinase by Tyrosine Phosphorylation (1996)

The first exon of the BCR gene encodes a new serine/threonine protein kinase. Abnormal fusion of the BCR and ABL genes, resulting from the formation of the Philadelphia chromosome (Ph), is the hallmark of Ph-positive leukemia. We have previously demonstrated that the Bcr protein is tyrosine phosphorylated within first-exon sequences by the Bcr-Abl oncoprotein. Here we report that in addition to tyrose 177 (Y-177), Y-360 and Y283 are phosphorylated in Bcr-Abl proteins in vitro. Moreover, Bcr tyrosine 360 is phosphorylated in vivo within both Bcr-Abl and Bcr. Bcr mutant Y177F had a greatly reduced ability to transphosphorylate casein and histone H1, whereas Bcr mutants Y177F and Y283F had wild-type activities. In contrast, the Y360F mutation had little effect on Bcr's autophosphorylation activity. Tyrosine-phosphorylated Bcr, phosphorylated in vitro by Bcr-Abl, was greatly inhibited in its serine/threonine kinase activity, impairing both auto- and transkinase activities of Bcr. Similarly, the isolation of Bcr from cells expressing Bcr-Abl under conditions that preserve phosphotyrosine residues also reduced Bcr's kinase activity. These results indicate that tyrosine 360 of Bcr is critical for the transphosphorylation activity of Bcr and that in Ph-positive leukemia, Bcr serine/threonine kinase activity is seriously impaired.
Orientational phase transition of tilted molecules moving in a planar layer—tentative model for the smectic-Cphase (1978)

A recent x-ray study, by De Jeu and De Poorter, of the smectic phases of heptyloxybenzylidene-pentylaniline shows that the individual molecules are tilted with respect to the layer normal in both the smectic-$A$ and the smectic-$C$ phases. We demonstrate here that a system of long molecules, moving within a planar layer, and making a fixed angle $\ensuremath{\epsilon}&gt;0$ with the layer normal, has a second-order transition from a phase with disordered tilt directions to a phase with the tilt directions aligned along some axis. It is suggested that this model phase transition underlies the smectic-$A$---smectic-$C$ transition, at least in those cases where the smectic-$A$ layer thickness is significantly smaller than the molecular length. In this model the effective tilt angle $\ensuremath{\alpha}$, as measured in optical and magnetic resonance experiments, grows continuously with increasing order of the tilt directions, and saturates at the value $\ensuremath{\alpha}=\ensuremath{\epsilon}$. On the other hand, the biaxiality ($\ensuremath{\Delta}$) in the molecular orientational order passes through a maximum and remains small at all temperatures; e.g., we find $|\ensuremath{\Delta}|&lt;6\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}2}$ for $\ensuremath{\epsilon}=30\ifmmode^\circ\else\textdegree\fi{}$. The phase transition is driven by the gains in translational entropy and total attractive energy which accompany an increase in order of the tilt directions. (At the transition temperature these effects balance the loss in orientational entropy.)
Use of achiral additives to increase the stereoselectivity in Rh(ii)-catalyzed cyclopropanations (2010)

We describe our studies on the effect of various Lewis bases and Brønsted acids as achiral additives on the stereoselectivity of some Rh(ii)-catalyzed cyclopropanations.
Accelerated cheese ripening: a method for increasing the number of lactic starter bacteria in cheese without detrimental effect to the cheese-making process, and its effect on the cheese ripening (1975)

Summary A method is outlined for accelerating ripening in Swedish semihard cheese by increasing the number of lactic starter bacteria present in the cheese without impairing characteristic texture and flavour. In addition to the normal starter inoculum, suitable lactic starter bacteria whose lactic-acid-producing activity had been greatly reduced by previous sublethal heat treatment, were added to the cheesemilk. When suspensions of streptococci and lactobacilli cultivated at a constant pH were heated at 59 and 69°C respectively acid production was retarded by 5–10 h, which was found to be sufficient for the cheese-making. Proteolysis was lowered only 10–30% by these heating temperatures. Bacterial cell suspensions, prepared by the methods outlined and added to the cheesemilk, were incorporated in cheese curd to extents depending on the amount added and the type of starter. The number in the final cheese could be increased to a maximum of 4–5 times that of control cheese. No adverse effect of the extra starter bacteria on pH, fat content and water content of cheeses 24-h old was observed. Proteolysis, measured as the increase in trichloroacetic acid and phosphotungstic acid (PTA)-soluble N, increased with increasing number of cells in the cheese. Organoleptic judgements showed a positive correlation ( r = 0·81) between taste and PTA-soluble N, which in turn was influenced by the number of cells in the final cheeses.
Interactive map of seismic hazard for nuclear facilities, Czech Republic&#160; (2022)

&amp;lt;p&amp;gt;The main aim of this project is create an interactive map of seismic hazard of the territory of the Czech Republic and the system of its upgrading. The map will fulfill the recommendation of the International Atomic Energy Agency for evaluation of seismic hazard at the sites of nuclear facilities. It will serve as the background material during the process of approving of seismic safety of nuclear infrastructure. The interactive map will enable also to improve seismic hazard assessment for non-nuclear buildings, facilities and infrastructure. The system of continual upgrading will enable to include the new scientific results in the field of seismic hazard and experience from new earthquakes.&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;Czech Republic is situated in an intraplate region with low seismicity. The seismic hazard is relatively low, but not negligible. The seismic hazard is evaluated by probabilistic seismic hazard method, including construction of logic tree and deriving of seismic hazard curves. In areas, where no or just a few weak events are recorded, but significant earthquakes can occur from both geological and seismological point of view, the concept of diffused seismicity is applied.&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;Historical catalogs in weak-seismic regions cover a much shorter period than the average time between the strong (controlling) earthquakes. This cause a complicate evaluation of focal zone maximal magnitude parameter. Hence, a new method of maximal magnitude determination was developed. It uses Bayesian approach combining a priori information from wider region with historical earthquake catalogue resulting in probability distribution of maximum magnitude.&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;For the evaluation of the local conditions, the new Vs30 map of Czech Republic is prepared. The map combines method of Wald and Allen (2007), using topographic slope as a proxy for seismic site conditions and amplification, and new Vs30 field measurements on multiple locations in the area of study.&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;References:&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;Wald, J.W. and Allen, T.I (2007): Topographic Slope as a Proxy for Seismic Site Conditions and Amplification, doi: 10.1785/0120060267.&amp;lt;/p&amp;gt;
Immunology of cytomegalovirus: immunosuppressive effects during infections. (1984)

Acute CMV infection in the mouse results in depressed antibody production, IFN induction, lymphocyte proliferation responses to mitogens, allogeneic skin graft rejection, and clearance of certain bacteria and fungi from the blood stream. CMV mononucleosis in humans is associated with decreased lymphocyte proliferation responses to mitogens and herpesvirus antigens, decreased IFN production, and reversal of the T-helper to suppressor cell ratio. In recent studies, we have shown that NK activity is depressed after renal transplantation and the use of cyA, and is poorly enhanced by the addition of IFN to in vitro assays. In vitro induction of alpha-IFN as well as gamma-IFN by NDV and enterotoxin-A is also inhibited. These deficits may contribute to the severity of CMV infections in this patient population.
Nicotine Microaerosol Inhaler (1999)

The inhaler formulation used produces a microaerosol of sufficiently fine droplet size that mimics the puff-by-puff pulmonary arterial bolus nicotine delivery of tobacco smoke. The absence of combustion products such as heat, carcinogens and carbon monoxide permits safer nicotine delivery via the inhaler than is possible via smoked tobacco.
Client protection in wireless home networks (2011)

In-home wireless networks are currently available in every home today. However, the open nature of wireless medium and the increase of wireless traffic make it difficult for network operator to guarantee user experience of provided services. In this paper, we focus on multimedia services especially wireless IPTV that needs to be guaranteed by network operator. In order to avoid global degradation and to ensure per-client quality, we propose to use a fair-scheduler implementable with Quiet Element available in the IEEE 802.11 standard. Unlike most of existing schemes, our proposition is applicable to both downlink and uplink streams and can be implemented easily in real access point products. Performance evaluation is conducted using NS-3 and real house propagation maps.
Tunable picosecond blue and UV pulses from a diode-pumped laser system seeded by a gain-switched laser diode (1998)

International audience
Epoxy‐based adhesives filled with flakes ag‐coated copper as conductive fillers (2015)

The flake core–shell Cu‐Ag powders are prepared and characterized. Isotropic conductive adhesives (ICAs) filled with flake silver‐coated copper was prepared by using epoxide resin as matrix and tetraethylenepentamine as curing agent. The flake silver‐coated copper was characterized by scanning electron microscopy, X‐ray diffraction, energy dispersive X‐ray spectroscopy, and TG‐DTA. The results show Ag content in the surface of coated copper is up to 96.32%. Oxidation resistance of flake Cu‐Ag powders with high surface Ag content is improved greatly investigated by TG‐DTA. And bulk resistivity and shear strength of ICAs are measured. It was found that the percolation threshold of ICAs filled with flake Cu‐Ag powders is as low as 40 wt%. The ICAs have good overall performances. And the main influence factor on electric resistivity was analyzed. POLYM. COMPOS., 38:846–851, 2017. © 2015 Society of Plastics Engineers
New Heteroaromatic Compounds. XVII.1 Fluoro Derivatives of 10-Methyl-10,9-borazarophenanthrene2 (1963)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew Heteroaromatic Compounds. XVII.1 Fluoro Derivatives of 10-Methyl-10,9-borazarophenanthrene2Michael J. S. Dewar and Patrick J. GrisdaleCite this: J. Org. Chem. 1963, 28, 7, 1759–1762Publication Date (Print):July 1, 1963Publication History Published online1 May 2002Published inissue 1 July 1963https://pubs.acs.org/doi/10.1021/jo01042a006https://doi.org/10.1021/jo01042a006research-articleACS PublicationsRequest reuse permissionsArticle Views471Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts