gebhart/patrepeval huggingface dataset:
Heart Rate Variability is a Moderating Factor in the Workload-Injury Relationship of Competitive CrossFit™ Athletes. (2017)

Heart rate variability (HRV) is a popular tool for monitoring training adaptation and readiness in athletes, but it also has the potential to indicate early signs of somatic tissue overload prior to the onset of pain or fully developed injury. Therefore, the aim of this study was to investigate the interaction between HRV, workloads, and risk of overuse problems in competitive CrossFit™ athletes. Daily resting HRV and workloads (duration × session-RPE) were recorded in six competitive CrossFit™ athletes across a 16 week period. The Oslo Sports Trauma Research Center Overuse Injury Questionnaire was distributed weekly by e-mail. Acute-to-chronic workload ratios (ACWR) and the rolling 7-day average of the natural logarithm of the square root of the mean sum of the squared differences between R-R intervals (Ln rMSSD<sub>week</sub>) were parsed into tertiles (low, moderate/normal, and high) based on within-individual z-scores. The interaction between Ln rMSSD<sub>week</sub> and ACWR on overuse injury risk in the subsequent week was assessed using a generalized linear mixed-effects model and magnitude-based inferences. The risk of overuse problems was substantially increased when a 'low' Ln rMSSD<sub>week</sub> was seen in combination with a 'high' ACWR (relative risk [RR]: 2.61, 90% CI: 1.38 - 4.93). In contrast, high ACWRs were well-tolerated when Ln rMSSD<sub>week</sub> remained 'normal' or was 'high'. Monitoring HRV trends alongside workloads may provide useful information on an athlete's emerging global pattern to loading. HRV monitoring may therefore be used by practitioners to adjust and individualise training load prescriptions, in order to minimise overuse injury risk.
Improving Compositionality of Neural Networks by Decoding\n Representations to Inputs (2021)

In traditional software programs, it is easy to trace program logic from\nvariables back to input, apply assertion statements to block erroneous\nbehavior, and compose programs together. Although deep learning programs have\ndemonstrated strong performance on novel applications, they sacrifice many of\nthe functionalities of traditional software programs. With this as motivation,\nwe take a modest first step towards improving deep learning programs by jointly\ntraining a generative model to constrain neural network activations to "decode"\nback to inputs. We call this design a Decodable Neural Network, or DecNN. Doing\nso enables a form of compositionality in neural networks, where one can\nrecursively compose DecNN with itself to create an ensemble-like model with\nuncertainty. In our experiments, we demonstrate applications of this\nuncertainty to out-of-distribution detection, adversarial example detection,\nand calibration -- while matching standard neural networks in accuracy. We\nfurther explore this compositionality by combining DecNN with pretrained\nmodels, where we show promising results that neural networks can be regularized\nfrom using protected features.\n
Tankyrase Is a Golgi-associated Mitogen-activated Protein Kinase Substrate That Interacts with IRAP in GLUT4 Vesicles (2000)

The poly(ADP-ribose) polymerase tankyrase was originally described as a telomeric protein whose catalytic activity was proposed to regulate telomere function. Subsequent studies revealed that most tankyrase is actually extranuclear, but a discordant pattern of cytoplasmic targeting was reported. Here we used fractionation and immunofluorescence to show in 3T3-L1 fibroblasts that tankyrase is a peripheral membrane protein associated with the Golgi. We further colocalized tankyrase with GLUT4 storage vesicles in the juxtanuclear region of adipocytes. Consistent with this colocalization, we found that tankyrase binds specifically to a resident protein of GLUT4 vesicles, IRAP (insulin-responsive amino peptidase). The binding of tankyrase to IRAP involves the ankyrin repeats of tankyrase and a defined sequence ((96)RQSPDG(101)) in the IRAP cytosolic domain (IRAP(1-109)). Tankyrase is a novel signaling target of mitogen-activated protein kinase (MAPK); it is stoichiometrically phosphorylated upon insulin stimulation. Phosphorylation enhances the poly(ADP-ribose) polymerase activity of tankyrase but apparently does not mediate the acute effect of insulin on GLUT4 targeting. Taken together, tankyrase is a novel target of MAPK signaling in the Golgi, where it is tethered to GLUT4 vesicles by binding to IRAP. We speculate that tankyrase may be involved in the long term effect of the MAPK cascade on the metabolism of GLUT4 vesicles.
CPU sharing techniques for performance isolation in multi-tenant relational database-as-a-service (2013)

Multi-tenancy and resource sharing are essential to make a Database-as-a-Service (DaaS) cost-effective. However, one major consequence of resource sharing is that the performance of one tenant's workload can be significantly affected by the resource demands of co-located tenants. The lack of performance isolation in a shared environment can make DaaS less attractive to performance-sensitive tenants. Our approach to performance isolation in a DaaS is to isolate the key resources needed by the tenants' workload. In this paper, we focus on the problem of effectively sharing and isolating CPU among co-located tenants in a multi-tenant DaaS. We show that traditional CPU sharing abstractions and algorithms are inadequate to support several key new requirements that arise in DaaS: (a) absolute and fine-grained CPU reservations without static allocation; (b) support elasticity by dynamically adapting to bursty resource demands; and (c) enable the DaaS provider to suitably tradeoff revenue with fairness. We implemented these new scheduling algorithms in a commercial DaaS prototype and extensive experiments demonstrate the effectiveness of our techniques.
Usefulness of a Highly Sensitive Urinary and Serum IL-6 Assay in Patients with Diabetic Nephropathy (2000)

The urinary IL-6 level seems to be a good indicator of diabetic nephropathy, and atherosclerotic changes were related to the serum IL-6 level. The serum IL-6 may, therefore, be useful in the evaluation of atherosclerosis including nephropathy.
Non-invasive biomarkers for monitoring the fibrogenic process in liver: A short survey (2009)

The clinical course of chronic liver diseases is significantly dependent on the progression rate and the extent of fibrosis, i.e. the non-structured replacement of necrotic parenchyma by extracellular matrix. Fibrogenesis, i.e. the development of fibrosis can be regarded as an unlimited wound healing process, which is based on matrix (connective tissue) synthesis in activated hepatic stellate cells, fibroblasts (fibrocytes), hepatocytes and biliary epithelial cells, which are converted to matrix-producing (myo-)fibroblasts by a process defined as epithelial-mesenchymal transition. Blood (non-invasive) biomarkers of fibrogenesis and fibrosis can be divided into class I and class II analytes. Class I biomarkers are those single tests, which are based on the pathophysiology of fibrosis, whereas class II biomarkers are mostly multiparametric algorithms, which have been statistically evaluated with regard to the detection and activity of ongoing fibrosis. Currently available markers fulfil the criteria of ideal clinical-chemical tests only partially, but increased understanding of the complex pathogenesis of fibrosis offers additional ways for pathophysiologically well based serum (plasma) biomarkers. They include TGF-beta-driven marker proteins, bone marrow-derived cells (fibrocytes), and cytokines, which govern pro- and anti-fibrotic activities. Proteomic and glycomic approaches of serum are under investigation to set up specific protein or carbohydrate profiles in patients with liver fibrosis. These and other novel parameters will supplement or eventually replace liver biopsy/histology, high resolution imaging analysis, and elastography for the detection and monitoring of patients at risk of developing liver fibrosis.
A Personalized Recommendation System Based on User Portrait (2019)

This paper focus on video recommendation in response to the explosive growth of movies which has made people in the dilemma of information overload for a long time. It is particularly important to push movies accurately. Regarding this situation, this paper studies how to recommend the most similar movies to users based on their interest tags and browsing behavior. Compared with the collaborative filtering algorithm, whose processing effect is not good confronting scoring data sparse problem. This paper makes full use of the movie review data, and the experimental data set is obtained by crawling the high-quality review of the Douban website. The experimental results show that the proposed method can effectively solve the problem of difficulty in calculating the similarity of the traditional recommendation algorithm when the user data set is incomplete, and the recommended effect is satisfactory.
Wavelet analysis of velocity dispersion of elastic interface waves propagating along a fracture (1995)

A wavelet analysis is performed on seismic waveforms of elastic interface waves that propagate along a fracture. The wavelet analysis provides a direct quantitative measure of spectral content as a function of arrival time. We find that the spectral content of the interface wave signals is not stationary, but exhibits increasing frequency content for later arrival times, representing negative velocity dispersion. The dispersion increases from −11 m/sec/MHz to −116 m/sec/MHz as the stress on the fracture is increased from 3.5 kPa to 33 MPa. The negative velocity dispersion agrees with predictions from the displacement‐discontinuity theory of the seismic response of fractures, and can be used to fit fracture stiffness.
MSIA--SRM assay for parathyroid hormone and vitamin D binding protein: correlation with clinical immunoassay methods and application to clinical samples (2013)

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
Vulnerabilities of Control Systems in Internet of Things Applications (2017)

In this paper, we present some initial results about vulnerability of control systems that can be used in Internet of Things (IoT) applications. Up to our best knowledge, this paper is the first study about vulnerability of applied control systems in general, and especially in the IoT environment. The purpose of this paper is to examine fundamentals of linear control systems and consider vulnerability of its main features and concepts used in IoT applications under potential malicious attacks. We examine vulnerabilities of system stability, controllability, observability, design of feedback loops, and design and placement of sensors and controllers (actuators). The detailed study is limited to the most important vulnerability issues in time-invariant, unconstrained, deterministic, and linear physical systems. Several interesting and motivating examples are provided. We have outlined also some basic vulnerability studies for time-invariant nonlinear unconstrained systems, and indicate that such a study is particularly needed for distributed parameter systems that are very prone to outside physical and cyber-attacks.
ChemInform Abstract: REACTIONS OF A HETEROCYCLIC SYSTEM WITH AMBIDENT REACTIVITY (1982)

Abstract Die Ester (I) lagern sich im alkalischen Medium in das bicyclische Triazathia‐System (II) um, das mit der Triazin‐Form (III) in einem lösungsmittelabhängigen Gleichgewicht steht.
Growth Mechanism of (111)-Textured 3C-SiC Films on Si(100) Substrates (2003)

Heteroepitaxial growth of 3C-SiC films on a Si(100) substrate can be achieved by chemical vapor deposition Under certain processing conditions, there is a transition from 3-D epitaxial islands to columnar grains, modifying the film texture from (100) to (111). This transition is more pronounced with increasing thickness and decreasing deposition temperature. The current work uses transmission electron microscopy to characterize the microstructure and investigate the mechanism of 3C-SiC film growth on Si(100) substrates.
Congestion Control with Deterministic Service Delay Guarantee (2022)

To meet the ever-increasing demand for mission-critical applications, the deterministic service delay guarantee from the application prospective has become an important metric for congestion control in end-to-end communications. In this paper, we propose a two-timescale congestion window control (TCWC) mechanism with delay-aware priority based on TCP Vegas. Different from the existing works only considering the network delay, we formulate the network utility maximization problem for congestion control by adding additional flow queuing delay at the source node to guarantee the deterministic service delay constraints. By designing a virtual queue, we transform the delay constraint to the time-averaged queue stability, and solve it in each time slot according to the Lyapunov drift-plus-penalty method. Then we obtain the adjustment strategy of congestion window according to Lagrangian duality theory. For further guarantee the service delay, we apply extreme value theory (EVT) to evaluate the priorities of different flows, which determines the update rate of congestion window. Finally, simulation results show that our algorithm can significantly reduce the average service delay and achieve better delay guarantee compared to traditional TCP Vegas.
Upregulation of Membrane‐Bound CD40L on CD4+ T cells in Women with Primary Sjögren's Syndrome (2013)

Epigenetic deregulation of genes encoded on the X chromosome as reported for CD40L in lupus could explain the female predominance of autoimmune diseases. We compared CD40L expression on CD4(+) T cells from primary Sjögren's syndrome (pSS) women and healthy controls and investigated DNA methylation patterns of the promoter and enhancer regions of CD40L. The expression of CD40L on activated CD4(+) T cells was higher in patients with pSS than controls after phorbolmyristate acetate and ionomycin activation (P = 0.02). CD40L mRNA level in CD4(+) T cells did not differ between patients with pSS and controls and was similar in both groups in cultures treated with the demethylating agent 5-azacytidine C. Pyrosequencing analysis revealed no significant differences in methylation profiles between patients and controls. Inducible membrane-bound CD40L on CD4(+) T cells is increased in patients with pSS but was not related to epigenetic deregulation by demethylation patterns of the regulatory regions of CD40L.
A predictable storage model for scalable parallel DW (2011)

Star schema model, has been widely used as the facto DW storage organization on RDBMS. Business measures are stored in a central fact table along with a set of foreign keys referencing dimension tables. While this storage organization offers a good trade-off between storage size and performance for a single node, it doesn't scale in a predictable manner in shared-nothing parallel architectures. Although fact tables can be linearly partitioned among nodes, the same doesn't apply to dimensions, which unbalances (increases) the dimensions/fact_table size ratio, and consequently introduces limits to the number of parallel nodes. In this paper we propose and evaluate a parallel DW storage model, that overcomes these limitations and deliver optimal speed-up and scale-up capabilities with top efficiency. We use the TPC-H benchmark to evaluate the scalability and efficiency of the proposed model.
Formulations of the capacity planning problem considering manufacturing flexibility (1996)

This paper addresses the problem of determining the capacity requirements for a manufacturing system that consists of versatile metal removing machines, each of which may be configured to perform several different operations at varying levels of efficiency and cost. The number of each machine type required and the assignment of each machine type to different processes are determined by minimizing the sum of machine amortization costs and operating costs. Alternative formulations are presented to address non-splitting of a batch and non-splitting of the processing of a part. The formulations are illustrated using numerical examples.
Infrared techniques for detecting carbonization at onset of device failure (1997)

We describe the design, and development of an infrared detection system which detects the onset of carbonization of fluoropolymers in the presence of up to 60 watts of 1.06 micrometer laser energy. This system is used to shut down a therapeutic laser system before significant damage is done to a laser delivery device and patient. Black body radiation emitting from the diffusion tip is transmitted, backwards, through the same optical fiber as the therapeutic wavelength. Using a high power 1.06 micrometer laser mirror at 45 degrees, most of the 1.06 micrometer light is reflected while the black body radiation is passed to a holographic notch filter which further filters the signal. Still more filtering was needed before the 1.1 to 2 micrometer signal could be detected within the presence the therapeutic light using an extended indium gallium arsenide photodetector. There was still a significant detected offset which increased with laser power which necessitated a means to automatically null the offset for different laser power settings. The system is designed to be used with any unmodified laser system. It interfaces directly to or in series with most common external safety interlocks and can be used with various diffusing tips, probes or bare fibers.
Transradial approach for renal artery stenting (2001)

Percutaneous interventional procedures in the renal arteries are usually performed using a femoral or brachial vascular access. The transradial approach, which has been extensively investigated for coronary angiography and intervention, could be an attractive new technique for renal artery angioplasty and stenting. In 18 patients with hemodynamically relevant unilateral renal artery stenosis (mean diameter stenosis, 83% +/- 18%; right, n = 7; left, n = 11), interventional treatment with PTA and stenting was performed using a left (n = 16) or right (n = 2) radial artery access. Indications for the transradial approach were acute aorto-renal angles or severe peripheral arterial obstructions. After engagement of the renal artery ostium with a 6 Fr Multipurpose guiding catheter (length, 125 cm; Cordis) the stenosis was passed with a 0.014" guidewire followed by stent implantation (ACS Multi-Link RX Ultra, Guidant; length, 18 mm; diameter, 5 mm). Direct stenting was successfully performed in 16 cases. Predilatations were required in two cases. In five patients, optimal stent expansion was achieved by additional postdilatations. A primary technical success (residual stenosis < 30%) could be achieved in all cases. There were no periprocedural complications. According to color-coded doppler ultrasound, all access site arteries showed a normal perfusion. Clinically blood pressure control was improved in 11 patients with a significant reduction in systolic and diastolic blood pressure values. Serum creatinine values dropped from 1.81 +/- 0.3 mg/dl to 1.49 +/- 0.3 mg/dl (P < 0.001). Transradial renal artery angioplasty and stenting is technically feasible and safe. Particularly in patients with unfavorable vessel anatomy, this new cranio-caudal approach is an attractive alternative technique.
An adaptive technique for the enhanced fusion of low-light visible with uncooled thermal infrared imagery (2002)

A new algorithm is introduced that performs spatially adaptive enhancement on low-light visible and infrared images of the same scene and fusion of these into one composite image. The algorithm involves low-pass/high-pass filtering and simple nonlinear operations that can be table driven. Examples of the processing on image data collected in field tests are given.
Matrix Metalloproteinases 2 and 9 in Indomethacin-Induced Rat Gastric Ulcer (2000)

The restoration of functional connective tissue is a major goal of the wound healing process. The 72- and 92-kD gelatinases (MMP-2 and MMP-9) are extracellular matrix metalloproteinases (MMPs), which are known to degrade type IV and V collagens and gelatin, and have a potential role in wound healing. The spatial and temporal gelatinolytic activities of MMP-2 and MMP-9 were analyzed as a function of ulcer age, in homogenates of rat, indomethacin-induced, chronic gastric ulcers. The rats were sacrificed on 1, 3, 7, 12, 18, 24 and 28 days after subcutaneous indomethacin injections. Zymographic analyses revealed elevated activation of MMP-9 and latent and active MMP-2 in gastric ulcers, when compared to gastric tissue from non-indomethacin-treated rats. The intact tissue and tissue from ulcerous lesions contained MMP-2. The highest activity of MMP-2 was found in 3 day gastric ulcers and returned to the control level by day 24. MMP-9 was not present in the intact tissue and the highest gelatinolytic activity of MMP-9 was also observed on the 3rd day after administration of indomethacin. The activity thereafter decreased and returned to the control level by day 24. In situ hybridization was used to evaluate which cells synthesize MMP-2 and MMP-9. MMP-2 was seen mostly in fibroblast-like cells in the submucosa and MMP-9 in macrophage-like cells in the mucosa on the margins of the ulcers. Thus, we conclude that these two MMPs seem to have different functions during the gastric ulcer injury/healing process. MMP-2 may participate in the physiological turnover of the gastric extracellular matrix, whereas MMP-9 may be important in the early phase of gastric ulcer formation and also in the healing process.
Theory of gyro-backward-wave-oscillators with tapered waveguide and magnetic field (1995)

The theory of gyro-backward-wave-oscillators (gyro-BWOs) with variable interaction region parameters is developed in a general form. It is shown that the tapering of a waveguide and/or an external magnetic field may enhance the orbital efficiency from 19% (for constant parameters) to 56%. Some designs realizing such an efficiency are considered.
Investigation of Paramagnetic Defects in SiCN and SiCO-based Wafer Bonding (2020)

We present fundamental exploration of inorganic dielectric wafer-to-wafer (W2W) bonding by electron spin resonance (ESR) to assess the function of dangling bond-type interface defects. As compared to a standard PECVD SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> which contains negligible dangling bonds (DBs), it is found that a substantial amount of silicon and carbon types of DBs, as high as 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">14</sup> cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-2</sup> , are present in the pre-bonding layer of SiCN and SiCO, mainly as a result of surface modification by means of low energy plasma activation prior to bonding. It is inferred that the evolution of DBs has a positive influence on improving the wafer bonding energy during post-bond anneal, in that the results suggest that a decrease of DBs translates into the formation of chemical bonds at the bonding interface.
[COGNITIVE CAPABILITIES OF PSYCHIATRIC INPATIENTS: A CHART REVIEW STUDY]. (2021)

The study indicates higher sensitivity of the Neuro-Behavioral-Cognitive Status Test than that of the Clock Drawing Test, when physical illnesses are present. Aditionally, according to the results of both tests, one may assume that a high level of education constitutes a protective element from cognitive deterioration in schizophrenia.