gebhart/patrepeval huggingface dataset:
A Model-Based Approach for the Measurement of Eye Movements Using Image Processing (1997)

This paper describes a video eye-tracking algorithm which searches for the best fit of the pupil modeled as a circular disk. The algorithm is robust to common image artifacts such as the droopy eyelids and light reflections while maintaining the measurement resolution available by the centroid algorithm. The presented algorithm is used to derive the pupil size and center coordinates, and can be combined with iris-tracking techniques to measure ocular torsion. A comparison search method of pupil candidates using pixel coordinate reference lookup tables optimizes the processing requirements for a least square fit of the circular disk model. This paper includes quantitative analyses and simulation results for the resolution and the robustness of the algorithm. The algorithm presented in this paper provides a platform for a noninvasive, multidimensional eye measurement system which can be used for clinical and research applications requiring the precise recording of eye movements in three-dimensional space.
The role of orlistat combined with lifestyle changes in the management of overweight and obese patients with polycystic ovary syndrome (2013)

Orlistat combined with lifestyle changes induces substantial weight loss in women with PCOS, resulting in improvements in IR, hyperandrogenemia and cardiovascular risk factors.
Comparative pharmacology in the rat of ketamine and its two principal metabolites, norketamine and (Z)-6-hydroxynorketamine (1986)

(Z)-6-Hydroxynorketamine (3), a secondary metabolite of the dissociative anesthetic agent ketamine (1), was synthesized, and its central nervous system (CNS) properties were compared to those of the parent drug and the primary metabolite, norketamine (2). Administration of compounds 1 and 2 to rats (40 mg/kg iv) produced general anesthesia and also led to marked increases in spontaneous locomotor activity during the postanesthetic recovery phase. These effects were of significantly longer duration with 1 than with 2. In contrast, the same dose of 3 produced neither general anesthesia nor CNS excitation, despite the fact that 3 entered brain tissue readily from the systemic circulation. It is concluded that the CNS effects of 1 are attenuated by metabolism to 2 and are abolished by subsequent hydroxylation to produce 3. Moreover, the results suggest that the desirable anesthetic properties of 1 and related arylcyclohexylamines may be inseparable from their ability to produce adverse postanesthetic emergence reactions.
Rabble without a cause (1985)

I first became interested in politics when I was a schoolboy. I used to read the Parliamentary Reports in The Times, and kept an annotated register of MPs. I think I classified them according to their distance from my own views, which at that time were roughly those held today by Mr Kinnock - that is, based on the assumptions that would be made by a rather naive 15-year-old. (My excuse is that I was a rather naive 15-year-old: what is Mr Kinnock's?)
Evaluation of the Radiolabeled Boronic Acid-Based FAP Inhibitor MIP-1232 for Atherosclerotic Plaque Imaging (2015)

Research towards the non-invasive imaging of atherosclerotic plaques is of high clinical priority as early recognition of vulnerable plaques may reduce the incidence of cardiovascular events. The fibroblast activation protein alpha (FAP) was recently proposed as inflammation-induced protease involved in the process of plaque vulnerability. In this study, FAP mRNA and protein levels were investigated by quantitative polymerase chain reaction and immunohistochemistry, respectively, in human endarterectomized carotid plaques. A published boronic-acid based FAP inhibitor, MIP-1232, was synthetized and radiolabeled with iodine-125. The potential of this radiotracer to image plaques was evaluated by in vitro autoradiography with human carotid plaques. Specificity was assessed with a xenograft with high and one with low FAP level, grown in mice. Target expression analyses revealed a moderately higher protein level in atherosclerotic plaques than normal arteries correlating with plaque vulnerability. No difference in expression was determined on mRNA level. The radiotracer was successfully produced and accumulated strongly in the FAP-positive SK-Mel-187 melanoma xenograft in vitro while accumulation was negligible in an NCI-H69 xenograft with low FAP levels. Binding of the tracer to endarterectomized tissue was similar in plaques and normal arteries, hampering its use for atherosclerosis imaging.
Effect of Porphyromonas gingivalis infection on gut dysbiosis and arthritis exacerbation in 1 mouse model (2020)

Abstract Background : Porphyromonas gingivalis (Pg) infection causes periodontal disease and is one of the causative bacteria of rheumatoid arthritis (RA) exacerbation. Gut microbiota dysbiosis has shown strong associations with systemic diseases, including RA, diabetes mellitus, and inflammatory bowel disease, and inoculation of periodontopathogenic bacteria (i.e. Pg) can alter gut microbiota composition. Therefore, this study investigated dysbiosis-mediated arthritis exacerbation by Pg oral inoculation in an experimental arthritis model mouse.Methods : Pg inoculation in the oral cavity twice a week for 6 weeks was performed to induce periodontitis in SKG mice. Concomitantly, a single intraperitoneal (i.p.) injection of laminarin (LA) was administered to induce experimental arthritis (Pg-LA mouse). Citrullinated protein (CP) and IL-6 levels in periodontal, intestinal, and joint tissues, and serum were measured by ELISA. Gut microbiota composition was determined by Miseq after DNA purification of mouse feces. Fecal microbiota transplantation (FMT) was performed by transferring Pg-RA-derived feces to normal mice. The effect of the Pg peptidylarginine deaminase (PgPAD) in arthritis progression was determined using PgPAD knockout mutant.Results : Periodontal alveolar bone loss and IL-6 in gingival tissue were induced by Pg oral infection, as well as severe joint destruction, increased arthritis scores (AS), and IL-6 and CP production in serum, joint, and intestinal tissues. Distribution of Deferribacteres and S24-7 was decreased, while CP was significantly increased in gingival, joint, and intestinal tissues of Pg-inoculated experimental arthritis mice compared to experimental arthritis mice without Pg inoculation. Further, FMT from Pg-inoculated experimental arthritis mice showed the reproduction of donor gut microbiota and resulted in severe joint destruction with increased IL-6 and CP production in joint and intestinal tissues. The maximum AS of FMT from Pg-inoculated experimental arthritis was much higher than that of donor mouse. However, inoculation of the PgPAD knockout mutant inhibited the elevation of arthritis scores, ACPA level in serum and reduced CP amount in gingival, joint, and intestinal tissues compared to Pg wild type inoculation .Conclusion : Pg oral infection exacerbated gut microbiota dysbiosis and joint destruction via increased CP generation.
Risk Assessment System for Oil and Gas Pipelines Laid in One Ditch Based on Quantitative Risk Analysis (2019)

In view of the vegetation reduction caused by the continuous construction of oil and gas pipelines, the pipelines have been designed to be laid in one ditch to reduce land occupation. However, owing to the small spacing between the pipelines, the fault correlation between pipelines has been proven to increase the potential hazard of adjacent pipelines and routing environments. The neglect of failure correlation in existing risk assessment methods leads to inaccurate results, which will lead to errors in maintenance decisions. Therefore, this paper proposed a risk assessment system for pipelines using this laying method. In the risk assessment, pipelines laid in one ditch (PLOD) were regarded as a series system relative to the routing environment. Therefore, the functional relationship between the total risk of the pipeline system and the risk of each pipeline was obtained by combining the engineering system reliability theory with the mathematical induction method. In addition, fuzzy set theory combined with fault tree analysis was used to calculate the failure probability of each pipeline in the system. Event tree analysis was used to sort out all the possible consequences of pipeline failure, and then the consequences were unified into monetary units to evaluate the severity of failure consequences. Finally, the two parts were merged into a bow-tie diagram to realize the risk management and control of the pipeline. Meanwhile, risk acceptance criteria were formulated to analyze risks and to guide pipeline maintenance. This system provides a complete risk assessment system for the pipeline system laid in one ditch, including the methods of risk identification, risk assessment, and risk analysis, which are of great significance to ensure the safety of the pipeline and the surrounding environment using this laying method.
EDITORIAL (2021)

Novo número da Revista Gestão e Sociedade, com nove artigos, evidenciando a diversidade temática e metodológica da exuberante produção acadêmica nacional.
Identification of Cervical Neoplasia Using a Simulation of Human Vision (2001)

Objective To determine whether a computer simulation of human vision could detect and discriminate cervical cancer precursors and cancer from normal epithelium. Methods The Georgia Tech Vision (GTV) system was trained to recognize normal and abnormal cervical features. GTV then assessed a new series of images to determine whether it could detect and diagnose cervical neoplasia without any a priori information about the images. Results After training on one set and testing on another set of images, GTV demonstrated 100% sensitivity and 98% specificity to detect cervical intraepithelial neoplasia 3 (CIN3). GTV also had 88% sensitivity and 93% specificity to detect cervical cancer following training on one set and testing on another set of digitized cervical colposcopic images. Conclusion This study demonstrated that GTV can detect CIN3 and cancer from digitized cervical colposcopic images. Furthermore, GTV could discriminate cervical cancer precursors and cancer from normal cervical epithelium, including immature metaplasia.
Cellular wave computers and CNN technology - a SoC architecture with xK processors and sensor arrays (2005)

Cellular wave computers and cellular nonlinear network (CNN) technology are discussed in this paper. It is a system-on-chip (SoC) architecture with xK processors and sensor arrays. The architectural lessons from the trends in manufacturing billion component devices when crossing the threshold of 100 nm feature size will determine the architecture, the elementary instructions, and the type of algorithms needed, hence also the complexity of the solution.
Suppression of intra-channel nonlinear penalties in high-speed transmissions with alternate polarization formats (2004)

We discuss simple methods to generate alternate polarization (APol) formats, and experimentally study the transmission performance of the APol formats for both 40-Gb/s dispersion-managed (DM) systems and 10-Gb/s DM-soliton systems.
Persistence, Transmission, and Virulence Characteristics ofAeromonasStrains in a Duckweed Aquaculture-Based Hospital Sewage Water Recycling Plant in Bangladesh (2006)

The persistence and transmission of Aeromonas in a duckweed aquaculture-based hospital sewage water treatment plant in Bangladesh was studied. A total of 670 samples from different sites of the hospital sewage water treatment plant, from feces of hospitalized children suffering from diarrhea, from environmental control ponds, and from feces of healthy humans were collected over a period of three years. In total, 1,315 presumptive Aeromonas isolates were biochemically typed by the PhenePlate rapid screening system (PhP-AE). A selection of 90 representative isolates was further analyzed with PhenePlate (PhP) extended typing (PhP-48), fatty acid methyl ester analysis, and amplified fragment length polymorphism (AFLP) fingerprinting. In addition, the prevalence of the putative virulence factors hemolysin and cytotoxin and the presence of the cytolytic enterotoxin gene (AHCYTOEN) were analyzed. Aeromonas was found at all sites of the treatment plant, in 40% of the samples from environmental control ponds, in 8.5% of the samples from hospitalized children suffering from diarrhea, and in 3.5% of samples from healthy humans. A significantly high number of Aeromonas bacteria was found in duckweed, which indicates that duckweed may serve as a reservoir for these bacteria. PhP-AE typing allowed identification of more than 192 distinct PhP types, of which 18 major PhP types (MTs) were found in multiple sites and during several occasions. AFLP fingerprinting revealed the prevalence of genotypically indistinguishable Aeromonas isolates among certain PhP MTs recovered from different sampling occasions and/or at multiple sites. Hemolytic and cytotoxic activities were observed in 43% of the tested strains, whereas 29% possessed the cytolytic enterotoxin gene AHCYTOEN. Collectively, two specific MTs associated with diarrhea were shown to exhibit high cytotoxicity. Furthermore, all tested isolates of these major types were positive for the cytolytic enterotoxin gene. In conclusion, our data indicate that certain phenotypically and genotypically stable clonal lineages of Aeromonas have persisted in the treatment system for a prolonged period and might spread from the hospitalized children suffering from diarrhea to fish produced for human consumption through the sewage water treatment system.
Inkjet Printing of Low-Temperature Cured Silver Patterns by Using AgNO3/1-Dimethylamino-2-propanol Inks on Polymer Substrates (2011)

1-Dimethylamino-2-propanol (DP) was added to silver nitrate to fabricate silver conductive lines by inkjet printing at low sintering temperatures on flexible PET substrates. Using an optimal ratio of a mixed solvent (ethanol and ethylene glycol), the morphology of the pattern surface and the formation of coffee-rings could be controlled. X-ray diffraction (XRD) analysis indicated that the AgNO3/DP inks were converted to silver completely at low temperatures. Using the AgNO3/DP inks, continuous and smooth silver conductive lines with a resistivity of 1.37 ± 0.44 × 10–5 Ω cm were fabricated at 100 °C by an inkjet printing system. This resistivity was close to the resistivity of bulk silver.
Preface of the “Mathematical Modelling of Hydrological Sciences” (2016)

First Page
Fate of Naphthalene in Laboratory-Scale Bioretention Cells: Implications for Sustainable Stormwater Management (2011)

Bioretention cells are increasingly popular in low-impact development as a means to sustainably mitigate the environmental problems associated with stormwater runoff. Yet, much remains to be known regarding the removal and ultimate fate of pollutants such as petroleum hydrocarbons in bioretention cells. In this work, laboratory-scale bioretention cells were constructed inside sealed glass columns. The columns were periodically spiked with (14)C-naphthalene over a 5-month period and the fate of this representative hydrocarbon and the influence of vegetation on naphthalene fate was studied. Three column setups were used: one planted with a legume (Purple Prairie Clover, Dalea purpureum), one planted with grass (Blue-Joint Grass, Calamagrostis canadensis), and one unplanted (i.e., control). Overall naphthalene removal efficiency was 93% for the planted columns and 78% for the control column. Adsorption to soil was the dominant naphthalene removal mechanism (56-73% of added naphthalene), although mineralization (12-18%) and plant uptake (2-23%) were also important. Volatilization was negligible (<0.04%). Significant enrichment of naphthalene-degrading bacteria occurred due to contaminant exposure and plant growth as evidenced by increased biodegradation activity and increased naphthalene dioxygenase gene concentrations in the bioretention media. This research suggests that bioretention is a viable solution for sustainable petroleum hydrocarbon removal from stormwater, and that vegetation can enhance overall performance and stimulate biodegradation.
Six-Year Follow-up of a Trial of Antenatal Vitamin D for Asthma Reduction (2020)

Vitamin D supplementation during the prenatal period alone did not influence the 6-year incidence of asthma and recurrent wheeze among children who were at risk for asthma. (Funded by the National Heart, Lung, and Blood Institute; VDAART ClinicalTrials.gov number, NCT00920621.).
Polyisobutylene-Anchored N-Heterocyclic Carbene Ligands (2009)

The synthesis of polyisobutylene (PIB)-supported N-heterocyclic carbenes (NHCs) that are useful as ligands for recoverable/recyclable organometallic complexes is described. Both PIB-bound carbenes analogous to SIMes and IMes as well as carbene precursors bound to PIB via 1,2,3-triazoles by alkyne-azide couplings are described. Both Ag(I) and Ru(II) complexes of these carbenes are shown to be phase selectively soluble in heptane. Hoveyda-Grubbs second-generation catalysts containing a PIB-supported NHC have also been used to catalyze ring-closing metathesis.
ApproxDNN: Incentivizing DNN Approximation in Cloud (2020)

Service providers leverage discounted prices of reserved instances offered by cloud providers to amortize their operational costs. They reserve a certain number of instances to cover a significant portion of their computing resource requirements, and further employ on-demand instances to cover remaining requirements not satisfied by the reserved instances. Because of the higher price of on-demand instances, service providers seek to lower their usage to minimize operational costs. In this work, we propose ApproxDNN approach for Machine Learning as a Service to reduce operational costs of service providers by incentivizing approximate results, based on the capabilities of cutting-edge GPUs and a discounted pricing model. When the deadlines of jobs submitted by users are very tight, a service provider might not be able to execute all of them on reserved instances under the default precision. In such cases, Ap- proxDNN leverages the reduced-precision instructions to reduce the execution time of the jobs with slight reduction in their final accuracy, and consequently, to minimize the employment of on- demand instances. To incentivize users to accept the approximate results of reduced-precision instructions, ApproxDNN offers them a discounted price for the service based on a newly designed pricing model. Our proposed pricing model of ApproxDNN guarantees lower or equal cost for service providers compared to the conventional method that solely depends on employment of on-demand instances in case of the reserved instance shortage. We employ real-world traces to conduct an extensive set of experiments and evaluate the performance of our proposed approach. The results show that ApproxDNN reduces the cost of service providers by 18%, while never exceeding the cost of the conventional method and slightly affecting the accuracy by 0.14%.
Linear sequence-to-sequence alignment (2004)

We present a novel approach for temporally aligning N unsynchronized sequences of a dynamic 3D scene, captured from distinct viewpoints. Unlike existing methods, which work for N = 2 and rely on a computationally-intensive search in the space of temporal alignments, we reduce the problem for general N to the robust estimation of a single line in RN. This line captures all temporal relations between the sequences and can be computed without any prior knowledge of these relations. Experimental results show that our method can accurately align sequences even when they have large mis-alignments (e.g., hundreds of frames), when the problem is seemingly ambiguous (e.g., scenes with roughly periodic motion), and when accurate manual alignment is difficult (e.g., due to slow-moving objects).
Speed-up Method of Rotation Template Matching Based on Optimization of Manifold's Shape (2017)

Machine vision technology is important because it is used for automated assembly or visual inspections in factories. Template matching is one of the general recognition methods used for this. But, this method need to match a large number of templates to detect rotated objects in an acquired image. Therefore, it creates computing time problems. We solve this problem by proposing fast matching method using “manifolds”. Here, “manifolds” means trajectories in the multi-dimensional space. They comprise continuous points that correspond to multiple images. Since, the computing time depends on the manifold's shape, the proposed method reduced it by optimizing the manifold's shape. Experimental results showed the method achieved a 92.5% recognition rate and a 236 msec processing time.
Mean arterial pressure at 12, 22, 32 and 36 weeks' gestation in screening for pre-eclampsia (2015)

The performance of combined screening with maternal factors and MAP is superior in screening for early, compared to late, PE and, to a certain extent, improves with advancing gestational age at screening. Copyright © 2015 ISUOG. Published by John Wiley & Sons Ltd.
Accelerometer-based gesture recognition via dynamic-time warping, affinity propagation, &#x00026; compressive sensing (2010)

We propose a gesture recognition system based primarily on a single 3-axis accelerometer. The system employs dynamic time warping and affinity propagation algorithms for training and utilizes the sparse nature of the gesture sequence by implementing compressive sensing for gesture recognition. A dictionary of 18 gestures is defined and a database of over 3,700 repetitions is created from 7 users. Our dictionary of gestures is the largest in published studies related to acceleration-based gesture recognition, to the best of our knowledge. The proposed system achieves almost perfect user-dependent recognition and a user-independent recognition accuracy that is competitive with the statistical methods that require significantly a large number of training samples and with the other accelerometer-based gesture recognition systems available in literature.