gebhart/patrepeval huggingface dataset:
Epidemiology of Campylobacter infections among children of 0–24 months of age in South Africa (2022)

This study has delineated a high prevalence of Campylobacter spp. in the study cohort. Moreover, C. jejuni was found to be more prevalent than C. coli both of which were associated with diarrhea. These findings are of clinical and epidemiological significance.
Enumerating regulatory T cells in cryopreserved umbilical cord blood samples using FOXP3 methylation specific quantitative PCR (2020)

Epigenetic assessment offers significant advantages over flow cytometry for analysing cryopreserved CB; similar cell numbers were observed both in fresh and frozen samples. Furthermore, multiple epigenetic assessments can be performed from DNA extracted from small cryopreserved CB segments; often the only CB sample available for clinical studies.
Topics in Current Chemistry 221. Contrast Agents I:  Magnetic Resonance Imaging Edited by Werner Krause (International Project Management Therapeu-tics, Schering AG, Berlin). Springer-Verlag:  Berlin, Heidelberg, New York. 2002. x + 250 pp. $159.00. ISBN 3-540-42247-1. (2002)

ADVERTISEMENT RETURN TO ISSUEPREVBook ReviewNEXTTopics in Current Chemistry 221. Contrast Agents I: Magnetic Resonance Imaging Edited by Werner Krause (International Project Management Therapeu-tics, Schering AG, Berlin). Springer-Verlag: Berlin, Heidelberg, New York. 2002. x + 250 pp. $159.00. ISBN 3-540-42247-1.A. Dean SherryView Author Information University of Texas at DallasCite this: J. Am. Chem. Soc. 2002, 124, 45, 13639–13640Publication Date (Web):September 12, 2002Publication History Published online12 September 2002Published inissue 1 November 2002https://pubs.acs.org/doi/10.1021/ja025251hhttps://doi.org/10.1021/ja025251hbook-reviewACS PublicationsCopyright © 2002 American Chemical SocietyRequest reuse permissionsArticle Views194Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Diagnostic imaging,Gadolinium,Imaging agents,Magnetic resonance imaging Get e-Alerts
O-Cluster: scalable clustering of large high dimensional data sets (2003)

Clustering large data sets of high dimensionality has always been a challenge for clustering algorithms. Many recently developed clustering algorithms have attempted to address either handling data sets with a very large number of records and/or with a very high number of dimensions. We provide a discussion of the advantages and limitations of existing algorithms when they operate on very large multidimensional data sets. To simultaneously overcome both the "curse of dimensionality" and the scalability problems associated with large amounts of data, we propose a new clustering algorithm called O-Cluster. O-Cluster combines a novel active sampling technique with an axis-parallel partitioning strategy to identify continuous areas of high density in the input space. The method operates on a limited memory buffer and requires at most a single scan through the data. We demonstrate the high quality of the obtained clustering solutions, their robustness to noise, and O-Cluster's excellent scalability.
Identification of Nonlinear Vibrating Structures: Part II—Applications (1987)

A time-domain procedure for the identification of nonlinear vibrating structures, presented in a companion paper, is applied to a “calibration” problem which incorporates realistic test situations and nonlinear structural characteristics widely encountered in the applied mechanics field. The “data” set is analyzed to develop suitable, approximate nonlinear system representations. Subsequently, a “validation” test is conducted to demonstrate the range of validity of the method under discussion. It is shown that the procedure furnishes a convenient means for constructing reduced-order nonlinear nonparametric mathematical models of reasonably high fidelity in regard to reproducing the response of the test article under dynamic loads that differ from the identification test loads.
An evaluation of supplemental Vitamin D3 on growth performance of pigs pre- and postweaning, nursery feed preference, and serum 25(OH)D3 (2012)

Three experiments were conducted to evaluate the effects of supplementing different concentrations and sources of vitamin D3 on pig performance, feed preference, and serum 25(OH)D3. In Exp. 1, a total of 398 barrows from 80 litters (PIC 1050, initially 7 d of age) were used in a 38-d study in a 2 Ã— 2 factorial to determine the effects of vitamin D3 suppleÂ¬mentation from either a single oral dose or from high levels of vitamin D3 in early nursÂ¬ery diets on pig performance and serum 25(OH)D3. On d 7 after birth, matched sets of pigs within litters were allotted to 1 of 2 oral dosages (none or 40,000 IU vitamin D3) in a randomized complete block design. Pigs were weighed at d 7 and at weaning (d 21). Following weaning, a subset of 300 barrows were used from d 21 to 45 to determine the effects of the previously administered oral vitamin D3 and 2 levels of dietary vitamin D3 (625 or 6,250 IU/lb; 0.80% Ca and 0.63% available P) from weaning to d 31 on pig growth and serum 25(OH)D3. A common diet containing 625 IU/lb of vitamin D3 (0.70% Ca and 0.47% available P) was fed from 31 to 45 d of age. No dose Ã— diet interÂ¬actions (P > 0.09) were observed. Serum 25(OH)D3 increased (P < 0.01) on d 21 and tended to increase on d 31 after dosing pigs with oral vitamin D3 prior to weaning. On d 31, serum concentrations increased with increasing dietary vitamin D3 levels (P < 0.01). Weaning weight was not influenced (P > 0.17) by the oral dose of vitamin D3. Supplementing vitamin D3 by either dose or diet did not influence (P > 0.23) nursÂ¬ery performance. In Exp. 2, a total of 864 pigs (PIC TR4 Ã— FAST ADN, initially 21 d of age) were used in a 30-d study to determine the effects of water supplementation of vitamin D3 on nursery growth performance and serum 25(OH)D3. Upon arrival to the nursery (d 0), pigs were allocated to pens and pens were randomly allotted to 1 of 2 water vitamin D3 supplementation treatments (none or 4,000,000 IU/gal). There were 24 pigs/pen and 18 pens/treatment. Pigs were provided the water supplementation treatments from d 0 to 10. From d 10 to 30, pigs were administered water with no supplemental vitamin D3. Common diets were fed throughout the study and were
A novel Lagrangian-relaxation to the minimum cost multicommodity flow problem and its application to OSPF traffic engineering (2004)

The minimum cost multicommodity flow problem plays a central role in today's operations research theory with applications ranging from transportation and logistics to telecommunications network routing. In this paper, we introduce a novel Lagrangian-relaxation technique, which, given an initial feasible solution, can solve the minimum cost multicommodity flow problem as a sequence of single-commodity flow problems. Our methodology is best suited for OSPF traffic engineering, because it can rapidly improve a given path set towards approximate optimality while simultaneously provides the link weights, which implement the paths as shortest paths.
Enzymatic synthesis of cyclic triterpenes (2007)

This review covers recent advances in the chemistry and enzymology of squalene cyclase and oxidosqualene cyclase. The enzymatic cyclizations of squalene and oxidosqualene are the most remarkable steps in the biosynthesis of sterols and triterpenes. The polyenes are converted to various polycyclic triterpenes by different enzyme systems employing only small modification of the active-site. Recent crystallographic and structure-based mutagenesis studies as well as utilization of chemically synthesized active-site probes have begun to reveal intimate structural details of the enzyme-templated cyclization reactions. 126 References are cited.
Pt-free carbon-based fuel cell catalyst prepared from spherical polyimide for enhanced oxygen diffusion (2016)

The development of a non-precious metal (NPM) fuel cell catalyst is extremely important to achieve globalization of polymer electrolyte fuel cells due to the cost and scarcity of platinum. Here, we report on a NPM cathode catalyst prepared by the pyrolysis of spherical polyimide nanoparticles that contain small amounts of Fe additive. 60 nm diameter Fe-containing polyimide nanoparticles were successfully synthesized by the precipitation polymerization of pyromellitic acid dianhydride and 1,3,5-tris(4-aminophenyl)benzene with Fe(acac)3 (acac = acetylacetonate) as an additive. The particles were subsequently carbonized by multistep pyrolysis to obtain the NPM catalyst while retaining the small particle size. The catalyst has good performance and promising durability for fuel cell applications. The fuel cell performance under a 0.2 MPa air atmosphere at 80 °C of 1.0 A cm(-2) at 0.46 V is especially remarkable and better than that previously reported.
A Comparison of the Physical Behavior of Normal Articular Cartilage and the Arthroplasty Surface (1972)

A study of the rabbit metatarsophalangeal joints with arthroplasty surface and normal articular cartilage was done by using compression testing to compare the elastic and viscoelastic behaviors of these two surfaces. Consistent differences were observed. Articular cartilage exhibited less instantaneous deformation than the arthroplasty surface, that is, the cartilage was stiffer. Both the rate and magnitude of time-dependent deformation under constant load (creep) of the articular cartilage were less than that of the arthroplasty surface. These differences increased significantly as a function of load. However, within the range of three to twelve-month-old anthroplasties, the viscoelastic behavior remained approximately constant. Mechanical analogues were constructed in an attempt to characterize the physical behaviors of these tissues, and mathematical relations of the experimental data to the analogues were developed. The loading range used in this study was not felt to exceed physiological limits as no plastic or permanent deformation was observed. Our findings show that cartilage is superior to the anthroplasty surface for resistance to and for recovery from the repetitive and rapid deformations which might be experienced in normal joint function Clinical experience supports this finding. The difference in elastic and viscoelastic behaviors was related to histological and biochemical differences of the two surfaces.
Pinoresinol-Lariciresinol Reductases with Opposite Enantiospecificity Determine the Enantiomeric Composition of Lignans in the Different Organs ofLinum usitatissimumL. (2010)

Lignans in higher plants represent an ideal class of natural products to be investigated for the origin of stereochemical diversity since chiral lignans occur in pure enantiomeric form as well as in enantiomeric mixtures. Seeds of Linum usitatissimum contain 8S, 8'S-(+)- and 8R, 8'R-(-)-secoisolariciresinol [SS-(+)- and RR-(-)-secoisolariciresinol, respectively] as diglucosides (SS- and RR-secoisolariciresinol diglucosides) whereas aerial parts of flowering L. usitatissimum accumulate only lignans derived from RR-(-)-secoisolariciresinol. Pinoresinol-lariciresinol reductase (PLR) catalyzes two early steps in lignan biosynthesis. Up to now, only a cDNA encoding a PLR ( PLR-LU1) which is enantiospecific for the conversion of 8S, 8'S-(-)-pinoresinol (SS-pinoresinol) via 8S, 8'S-(-)-lariciresinol (SS-lariciresinol) to SS-(+)-secoisolariciresinol was cloned. Here we present the cloning of a cDNA encoding a RR-pinoresinol-RR-lariciresinol reductase ( PLR-LU2) from the leaves of L. usitatissimum which converts only RR-pinoresinol to RR-secoisolariciresinol. In leaves and stems of L. usitatissimum accumulating the 8R, 8'R-enantiomers of lignans, only PLR-LU2 was transcriptionally active. Both PLR-LU1 and PLR-LU2 transcripts were observed in seeds and contribute to the synthesis of SS- and RR-secoisolariciresinol, respectively. Thus, the enantiomeric composition of lignans in the organs of L. usitatissimum appears to be determined by the relative action of two PLRs with opposite enantiospecificities rather than by a single enzyme of low enantiospecificity.
Adaptive control for ZVS three phase full active bridge converter with ARCN (2012)

This paper presents an adaptive control for the auxiliary circuit, called ARCN (Auxiliary Resonant Commutating Network), used to achieve ZVS in full active bridge converters under a wide load range. Depending on the load conditions, the proposed control adapts the timing of the ARCN to minimize the losses. The principle of operation and implementation considerations are presented for a three phase full active bridge converter, proposing different methods to implement the control according to the specifications. The experimental results shown verify the proposed methodology.
Optimizing similarity-based image joins in a multimedia database (2010)

Commonly used content-based image retrieval systems focus on the problem of finding similar images for a given single query object out of a database of media objects. We consider a similarity-based image join of two image tables, where the image data components are represented by their respective feature vectors. For each image of the first table, similar images are looked up in the second table. Matching tuples are combined. We consider multiple joins which allows one to join a previous join result to another image table, and so on. Thus, each multiple join result tuple contains n images, if n tables are joined. An image of the result tuple is therefore not only similar to the image from its join partner, but also to the image similar to it. In this context, the paper presents processing and optimizing strategies for multiple similarity-based image joins and a cost model for integrating them in a multimedia database. The cost model is validated by an X-tree reference implementation. The presented strategies in this paper are currently been implemented in Oracle Multimedia.
Effects of an EP2 and EP3 Receptor Dual Agonist, ONO‐8055, on a Radical Hysterectomy‐Induced Underactive Bladder Model in Monkeys (2017)

We developed a neurogenic UAB model in primates. As ONO-8055 improved voiding function in this model to at least the same degree as DIS, this EP2 and EP3 receptor dual agonist has the potential to be a candidate for neurogenic UAB pharmacotherapy.
Correlation functions at two-dimensional criticality and projective transformations (1987)

We consider the form of two-point correlation function in an infi- nite strip with periodic boundary conditions at bulk criticality. Privman has derived this by a conformal mapping of the strip onto itself, without reference to the bulk result ${r}^{\mathrm{\ensuremath{-}}2x}$. We show that the mapping employed is in fact equivalent to a projective transformation of the \ensuremath{\infty} plane onto itself, and present an equivalent derivation in the bulk. Since invariance under the projective (sub) group has been extensively investigated, it does not appear that this method can be usefully generalized.
How to Measure and Interpret Coherence Loss in Magnetic Recording (1985)

Presentation d'une analyse spectrale et de coherence utilisee pour mesurer quantitativement les performances en enregistrement magnetique analogique, du point de vue, reponse frequentielle, retard, spectre de puissance limitee, coherence et rapport signal sur bruit
Size of the Permo-Triassic Bottleneck and Its Evolutionary Implications (1979)

Rarefaction analysis of extinctions in the Late Permian indicates that as many as 96 percent of all marine species may have died out, thus forcing the marine biosphere to pass through a small bottleneck. With such severity of extinction, chance elimination of certain biologic groups would have been probable. Some of the changes in biologic composition observed at the Permo-Triassic boundary may be explained as an evolutionary founder effect that followed the bottleneck.
Greater Tuberosity Notch: An Important Indicator of Articular-Side Partial Rotator Cuff Tears in the Shoulders of Throwing Athletes (2001)

We examined the location of rotator cuff tears, associated labral injuries, and notches on the greater tuberosity of the humeral head in shoulders of throwing athletes. Arthroscopic findings (rotator cuff tear, labral condition, and greater tuberosity notch) as well as other factors (duration of playing baseball, range of motion, and joint laxity) of 61 baseball players were retrospectively studied. The presence of a greater tuberosity notch was also evaluated for by plain radiographs. Forty patients had articular-side partial rotator cuff tears, most of which occurred in the interval between the supraspinatus and infraspinatus tendons. The existence of a rotator cuff tear was not related to the range of motion, joint laxity, the detachment of the superior glenoid labrum, or posterosuperior labral injury. Greater tuberosity notches were recognized in 38 shoulders by arthroscopy and most were detected on plain radiographs. The presence of a notch was significantly related to the existence of a rotator cuff tear, while the size of the notch was significantly related to the depth and width of the tear. The greater tuberosity notch seems to be one of the most important diagnostic indicators for a rotator cuff tear in throwing athletes.
Cat Scratch Disease Caused by Bartonella grahamii in an Immunocompromised Patient (2013)

Bartonella grahamii colonizes rodents worldwide and has been detected in questing Ixodes ricinus ticks. Here, the first human B. grahamii infection confirmed by multilocus sequence typing is reported. The route of transmission and clinical picture of the patient are similar to those seen in patients with cat scratch disease, which is typically diagnosed as a Bartonella henselae infection.
Regional Circulatory and Systemic Hemodynamic Effects of Diaspirin Cross-Linked Hemoglobin in the Rat (1994)

Diaspirin cross-linked hemoglobin (DCLHb) (Baxter Healthcare Corporation) is a promising resuscitative fluid. The effect of DCLHb (400 mg/kg, i.v.), on regional circulation and systemic hemodynamics was studied in male Sprague-Dawley rats using a radioactive microsphere technique. Systemic hemodynamics, distribution of cardiac output, regional blood flow and vascular resistance were determined before (baseline) and 15, 30 and 60 min after the administration of DCLHb. Infusion of an equal volume of saline did not produce any significant change in systemic hemodynamics or regional circulation. DCLHb produced an increase (79%) in the mean blood pressure which lasted for more than 60 min. Heart rate, cardiac output and stroke volume were not significantly affected, while total peripheral resistance was increased after the administration of DCLHb. DCLHb produced significant increases in blood flow to the heart, gastrointestinal tract (GIT), portal system and skin. The blood flow to the kidney, brain and musculoskeletal system was not significantly affected by DCLHb. The vascular resistance was not altered in the heart, brain, GIT, portal system, kidney or skin, but there was a marked increase in the vascular resistance in the musculoskeletal system. There was a significant increase in the percentage of cardiac output to visceral organs like heart, GIT and portal system, while a marked decrease in the percent cardiac output to musculoskeletal system was observed with DCLHb. It is concluded that the blood flow to most of the organs is either increased or is not affected by DCLHb.
Prediction of real-time particulate matter concentrations on highways using traffic information and emission model (2017)

The public raises concerns about the exposure to particulate matter (PM) which has been strongly associated with illness and mortality.However, most of the studies rely on the measurements from stationary monitoring sites which cannot capture the actual PM exposure for those people in or near the source.In this study, we first set up a comprehensive mobile monitoring platform to measure both PM concentration and traffic conditions on some major highways in Southern California.Then, we developed an integrated database to fuse different data sources and to facilitate the investigation of relationship between traffic conditions and highway PM concentration.Using the fused datasets and combining with Emission FACtor (EMFAC) model, contour plots based on estimated PM emissions were generated with the overlay of particle concentration measurements.Analyses of the results indicate that there are numerous particle concentration peaks cause by traffic congestions and vehicle acceleration.PM concentrations may be affected by traffic conditions on the other side of the highway as shown in both measurement and emission models.In view of the complicated physical nature of PM concentration on highways, we applied the Multivariate Adaptive Regression Splines (MARS) model to the integrated database, and identified the eleven traffic-related variables that have the most impacts on in-source PM concentration prediction.The high coefficient of determination (i.e., R 2 = 0.72) indicates the capability of the model to address the variance in PM concentration.
Supplementary Figure S5. from Functional Homologous Recombination Assay on FFPE Specimens of Advanced High-Grade Serous Ovarian Cancer Predicts Clinical Outcomes (2023)

&lt;p&gt;Example images of staining patterns.&lt;/p&gt;
A proteomic analysis of Psychrobacter articus 273‐4 adaptation to low temperature and salinity using a 2‐D liquid mapping approach (2006)

Psychrobacter 273-4 was isolated from a 20,000-40,000-year-old Siberian permafrost core, which is characterized by low temperature, low water activity, and high salinity. To explore how 273-4 survives in the permafrost environment, proteins in four 273-4 samples cultured at 4 and 22 degrees C in media with and without 5% sodium chloride were profiled and comparatively studied using 2-D HPLC and MS. The method used herein involved fractionation via a pH gradient using chromatofocusing followed by nonporous silica (NPS) RP-HPLC and on-line electrospray mass mapping. It was observed that 33 proteins were involved in the adaptation to low temperature in the cells grown in the nonsaline media while there were only 14 proteins involved in the saline media. There were 45 proteins observed differentially expressed in response to salt at 22 degrees C while there were 22 proteins at 4 degrees C. In addition, 5% NaCl and 4 degrees C showed a combination effect on protein expression. A total of 56 proteins involved in the adaptation to low temperature and salt were identified using MS and database searching. The differentially expressed proteins were classified into different functional categories where the response of the regulation system to stress appears to be very elaborate. The evidence shows that the adaptation of 273-4 is based primarily on the control of translation and transcription, the synthesis of proteins (chaperones) to facilitate RNA and protein folding, and the regulation of metabolic pathways.