gebhart/patrepeval huggingface dataset:
All Two-Dimensional Pseudocapacitive Sheet Materials for Flexible Asymmetric Solid-State Planar Microsupercapacitors with High Energy Density (2019)

With the rapid development of portable devices and wireless protocols, miniaturized energy storage units have become an important prerequisite. Although in-plane microsupercapacitors are emerging as competitive candidate devices, their practical applications have been severely hindered by their low energy density. Here, employing pseudocapacitive active materials working in complementary voltage windows, namely, manganese oxide (MnO<sub>2</sub>) and titanium carbide (Ti<sub>3</sub>C<sub>2</sub>), both in the two-dimensional sheet morphology, a flexible asymmetric interdigitated solid-state microsupercapacitor was assembled. Profiting from the perfect voltage complementarity of the two types of sheets, the high exposure of electrochemically active sites and the maximized utilization of the sheets due to the planar ion transport, the designed device achieved excellent electrochemical performance even when using a gel electrolyte. In particular, the device obtained a high specific capacitance of 106 F g<sup>-1</sup> (295 mF cm<sup>-2</sup>), a wide potential window (2 V), an ultrahigh rate performance (retaining 83% even with a 20-fold in current density to 20 A g<sup>-1</sup>), an excellent cycling stability (87% retention after 10<sup>4</sup> cycles at 10 A g<sup>-1</sup>), and a competitive energy density of 58 W h kg<sup>-1</sup> (162 μW h cm<sup>-2</sup>) that are even comparable to those of some microbatteries, while maintaining a high power density of 985 W kg<sup>-1</sup> (2.7 mW cm<sup>-2</sup>). Importantly, this outstanding electrochemical performance was also stably maintained under various bending conditions. These results indicate that two-dimensional pseudocapacitive sheet materials have a plethora of possibilities for constructing flexible and wearable devices.
Treatment of Patients with Acute Myelogenous Leukemia (1995)

Although it represents only 15-20% of all childhood acute leukemias, > 30% of deaths from leukemia are still a consequence of AML, and only 30-40% of children with newly diagnosed AML are expected to achieve a long-term remission. Greater advances in treatment are expected as headway is made in understanding the complex biology of this heterogeneous disease.
Nanotechnology in agricultural diseases and food safety. (2010)

SUMMARY Nanotechnology can be used for combating the plant diseases either by controlled delivery of functional molecules or as diagnostic tool for disease detection. Nanotechnology, nano particles and quantum dots (QD) have emerged as pivotal tool for detection of a particular biological marker with extreme accuracy. The possibilities in future as well as some success that have been achieved so far are discussed in this review. Diagnosis of a disease in its very early stage can play important role in treatment. Due to phenomenal advancement in nanotechnology, QDs have emerged as pivotal tool for detection of a particular biological marker with extreme accuracy. QDS being very photo-stable and optically sensitive can be used as labeling and can be easily traced with ordinary equipment. Early detection of tumor markers using quantum dots is proved to be boon for cancer diagnosis. Use of QDs has also helped in unlocking complex neurological phenomenon, such as molecular activities at synapse during neurotransmission. QDs also give important information about receptor movement if tagged with suitable antibodies. In short, optical stability and easy to handle properties have made QDs to remain at the apex of medical diagnostics. Key words: Nanotechnology, Nanoparticles, Quantum dots, Nano-carbon, Carbon Nanotubes, Nano silver, Nano Alumino-silicate, Nano-sensors, Nano-emulsion Madhuri Sharon et al. Nanotechnology in Agricultural Diseases and Food Safety. J Phytol 2/4 (2010) 83-92.
Increased trefoil factor 2 levels in patients with chronic kidney disease (2017)

In chronically damaged tissue, trefoil factor family (TFF) peptides ensure epithelial protection and restitution. In chronic kidney disease (CKD), TFF1 and TFF2 are reported to be upregulated. Especially in the early phase, CKD is associated with silently ongoing renal damage and inflammation. Moreover, many patients are diagnosed late during disease progression. We therefore sought to investigate the potential of TFF2 as biomarker for CKD. We followed 118 patients suffering from predialysis CKD and 23 healthy volunteers. TFF2 concentrations were measured using ELISA. Our results showed, that median TFF2 serum levels were significantly higher in patients with later CKD stages as compared to healthy controls (p < 0.001) or early stages (p < 0.001). In patients with mid CKD stages TFF2 serum levels were significantly higher than in healthy controls (p = 0.002). Patients with early or mid CKD stages had significantly higher TFF2 urine concentrations than later CKD stages (p < 0.001 and p = 0.009, respectively). Fractional TFF2 excretion differed significantly between early CKD stages and healthy controls (p = 0.01). ROC curve showed that TFF2 levels can predict different CKD stages (AUC > 0.75). In conclusion, urine and serum TFF2 levels of CKD patients show a different profile dependent on CKD stages. Whereas TFF2 urine levels continuously decreased with disease progression, TFF2 serum concentrations progressively increased from the early to later CKD stages, indicating changes in renal function and offering the potential to examine the course of CKD.
Scaling Factors in Aging of Gas-Filled Cellular Plastics (1990)

One of the techniques used to determine aging of gas-filled cellular plastics (GFCP) is to correlate the thermal resistance of thin material layers with that of full thickness boards Either models of aging or scaling factors may be used for this purpose. This paper discusses the concept of scaling factors relating aging of thin and thick layers of GFCP, and points out their limitations.
Bonds and bond derivatives (1999)

This book provides an introduction to bond markets and bond derivatives for students as well as for executives in commercial businesses and financial institutions. It also:

 Presents the essential elements of debt instruments in an intuitive manner; Covers updated institutional material, new sections on callable bonds and the yield to call, convertible bonds, and methods for estimating and modern models of term structure of interest rates, as well as a comprehensive discussion of bonds in the European Economic Union;
Analysis of Principle and Performance of a New 4DOF Hybrid Magnetic Bearing (2016)

To satisfy the requirement of magnetically suspended control moment gyroscope (MSCMG) that magnetic bearing can provide torque, a novel 4DOF hybrid magnetic bearing (HMB) with integrated structure was designed. Mathematical models of forces and torques are established by using equivalent magnetic circuit method. The current stiffness, displacement stiffness, tilting current stiffness and angular stiffness of the 4DOF hybrid magnetic bearing are derived by the mathematical models. Equivalent magnetic circuit method and finite element method (FEM) simulation results indicate that the force has a good linear relationship with both displacement and current, and the torque has a good linear relationship with angular displacement and current. The novel 4DOF HMB is capable of achieving control in both two radial translational degrees of freedom (DOF) and also two radial rotational DOFs. The 4DOF HMB is well adapted to MSCMG system, exhibiting advantages in the controllable DOF, light weight and easy to control.
ChemInform Abstract: Synthesis of 1,1,3,3‐Tetraalkylisoindolines Using a Microwave‐Assisted Grignard Reaction. (2008)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
STAT3-dependent CXC chemokine formation and neutrophil migration in streptococcal M1 protein-induced acute lung inflammation (2015)

Streptococcus pyogenes cause infections ranging from mild pharyngitis to severe streptococcal toxic shock syndrome (STSS). The M1 serotype of Streptococcus pyogenes is most frequently associated with STSS. Herein, it was hypothesized that STAT3 signaling might be involved in M1 protein-evoked lung inflammation. The STAT3 inhibitor, S3I-201, was administered to male C57Bl/6 mice before iv challenge with M1 protein. Bronchoalveolar fluid and lung tissue were harvested for quantification of STAT3 activity, neutrophil recruitment, edema, and CXC chemokine formation. Neutrophil expression of Mac-1 was quantified by use of flow cytometry. Levels of IL-6 and HMGB1 were determined in plasma. CXCL2-induced neutrophil chemotaxis was studied in vitro. Administration of S3I-201 markedly reduced M1 protein-provoked STAT3 activity, neutrophil recruitment, edema formation, and inflammatory changes in the lung. In addition, M1 protein significantly increased Mac-1 expression on neutrophils and CXC chemokine levels in the lung. Treatment with S3I-201 had no effect on M1 protein-induced expression of Mac-1 on neutrophils. In contrast, inhibition of STAT3 activity greatly reduced M1 protein-induced formation of CXC chemokines in the lung. Interestingly, STAT3 inhibition markedly decreased plasma levels of IL-6 and HMGB1 in animals exposed to M1 protein. Moreover, we found that S3I-201 abolished CXCL2-induced neutrophil migration in vitro. In conclusion, these novel findings indicate that STAT3 signaling plays a key role in mediating CXC chemokine production and neutrophil infiltration in M1 protein-induced acute lung inflammation.
Design Methodology for Power-Constrained Low Noise RF Circuits (2001)

The regulation of renin release is unusual in that intracellular calcium reportedly acts as an inhibitory second messenger. Increased calcium not only inhibits renin release but is a cofactor in nitric oxide synthesis. Also, nitric oxide can inhibit renin release. This study was done in vitro using rat renal cortical slices to determine whether calcium-mediated renin inhibition could be in part due to the concurrent production of nitric oxide. Renin concentration in the incubation medium was determined by radioimmunoassay for angiotensin I (Ang I) generation (in nanograms Ang I per hour per milligram per 30 minutes of incubation). In all studies, n = 6 to 17. In normal-calcium incubation medium (2.6 mmol/L), 10(-4) mol/L NG-monomethyl L-arginine, which blocks nitric oxide synthesis, caused an 18% increase in basal renin release (78.6 +/- 8.9 versus 66.7 +/- 5.8 [ng Ang I/h]/mg per 30 minutes incubation, P < .05). When calcium was eliminated from the incubation medium, basal renin release doubled (to 133.1 +/- 15.2 [ng Ang I/h]/mg per 30 minutes incubation, P < .001). Without calcium, inhibiting nitric oxide synthesis had no further effect on renin release (126.8 +/- 17.7 [ng Ang I/h]/mg per 30 minutes incubation). High-calcium medium (7.8 mmol/L) reduced basal renin release by half (30.8 +/- 4.8 [ng Ang I/h]/mg per 30 minutes incubation, P < .001), but inhibiting nitric oxide synthesis in high-calcium medium stimulated renin release by 50% (46.9 +/- 6.2 [ng Ang I/h]/mg per 30 minutes incubation, P < .005). Addition of the calmodulin inhibitor W-7 completely reversed the inhibition of renin by high-calcium medium.(ABSTRACT TRUNCATED AT 250 WORDS)
Progression of ocular sulfur mustard injury: development of a model system (2010)

Exposure of tissues to sulfur mustard (SM) results in the formation of protein and nucleotide adducts that disrupt cellular metabolism and cause cell death. Subsequent pathologies involve a significant proinflammatory response, disrupted healing, and long-term defects in tissue architecture. Following ocular exposure, acute corneal sequelae include epithelial erosions, necrosis, and corneal inflammation. Longer term, a progressive injury becomes distributed throughout the anterior chamber, which ultimately causes a profound remodeling of corneal tissues. In many cases, debilitating and vision-threatening injuries reoccur months to years after the initial exposure. Preliminary data in humans suffering from chronic epithelial lesions suggest that thymosin beta4 (Tbeta4) may be a viable candidate to mitigate acute or long-term ocular SM injury. To evaluate therapeutic candidates, we have developed a rabbit ocular exposure model system. In this paper, we report molecular, histological, ultrastructural, and clinical consequences of rabbit ocular SM injury, which can be used to assess Tbeta4 efficacy, including timepoints at which Tbeta4 will be assessed for therapeutic utility.
Beneficial effects of aCannabis sativaextract treatment on diabetes‐induced neuropathy and oxidative stress (2009)

Neuropathy is the most common complication of diabetes and it is still considered to be relatively refractory to most of the analgesics. The aim of the present study was to explore the antinociceptive effect of a controlled cannabis extract (eCBD) in attenuating diabetic neuropathic pain. Repeated treatment with cannabis extract significantly relieved mechanical allodynia and restored the physiological thermal pain perception in streptozotocin (STZ)-induced diabetic rats without affecting hyperglycemia. In addition, the results showed that eCBD increased the reduced glutathione (GSH) content in the liver leading to a restoration of the defence mechanism and significantly decreased the liver lipid peroxidation suggesting that eCBD provides protection against oxidative damage in STZ-induced diabetes that also strongly contributes to the development of neuropathy. Finally, the nerve growth factor content in the sciatic nerve of diabetic rats was restored to normal following the repeated treatment with eCBD, suggesting that the extract was able to prevent the nerve damage caused by the reduced support of this neurotrophin. These findings highlighted the beneficial effects of cannabis extract treatment in attenuating diabetic neuropathic pain, possibly through a strong antioxidant activity and a specific action upon nerve growth factor.
Effect of Nitrogen Application Timing on N Uptake byVitis labruscain a Short-Season Region (2004)

Fertilizer nitrogen (N) was applied to <i>Vitis labrusca</i> L. cvs. Niagara and Concord grapevines in Michigan at various times to determine its effect on soil N levels and fertilizer N recovery in vine tissues. Labeled ammonium nitrate (<sup>15</sup>NH<sub>4</sub><sup>15</sup>NO<sub>3</sub>) was applied to the soil beneath vines at a rate of 68 kg N/ha at different times between budbreak and six weeks after bloom. Soil was sampled at one-to two-week intervals after the fertilizer applications to follow the inorganic soil N dynamics. Vines were excavated at the time of commercial grape harvest to quantify fertilizer N recovery. All times of fertilizer application resulted in less than 20% uptake of the N applied. Vines fertilized at budbreak generally contained less fertilizer N and allocated a greater fraction of the fertilizer N to fruit and leaves than later times of application. Vines fertilized later in the season absorbed more fertilizer N and allocated more of it and total N to the roots than earlier times of application. Later applications resulted in more fertilizer N remaining in the top 90 cm of soil at the end of the season. Based on these findings, N application to vineyards in this short-season region was more efficient between bloom and six weeks after bloom than at budbreak.
Improved Polarized 2x2 MIMO Spatial Multiplexing Method for DVB-NGH System (2015)

Recently terrestrial digital broadcasting systems have experienced a growth with the demand of high-data rate. In order to meet such demand, the multiple-input multiple-output (MIMO) technology has received wide attention. This paper proposes a pre-coding method, which provides high-space channel correlation for the improved performance over terrestrial broadcasting channels when the MIMO spatial multiplexing (SM) is adopted for digital video broadcasting-next generation handheld systems. When signals with two different modulation orders are transmitted through two antennas, a method that is based on non-uniform power is also proposed for improved reception performance. To optimize the proposed method, phase shifting values for the pre-coding method and appropriate non-uniform power ratio are obtained. These obtained parameters are applied to a terrestrial broadcasting system, and then the performance improvement over the conventional SM is shown through computer simulations.
Stakeholder-Engaged Development of a Theory-Driven, Feasible, and Acceptable Approach to Concussion Education (2022)

Concussion education is widely mandated and largely ineffective. Recent consensus guidance on concussion education asserts the importance of (1) theory-driven programming that targets the team as a system and (2) working with end users throughout the development process, and considering issues such as feasibility, acceptability, and sustainability. Consistent with this guidance, and in collaboration with youth sport stakeholders in two regions of the United States, we developed a novel approach to concussion education: Pre-game safety huddles. Safety huddles have the following two core components: (1) athletes, coaches, and other stakeholders come together before the start of each game and (2) opinion leaders (coaches, referees) affirm the importance of care seeking for suspected concussion. The aim of this article is to provide an overview of the collaborative process through which we refined the safety huddle concept into an acceptable and feasible intervention with potential for sustainable implementation in diverse youth sports settings with minimal resource demands. In describing our process and discussing challenges and opportunities, we hope to provide an example for others seeking to develop and implement injury prevention interventions in youth sports settings.
Characterization of sludges for predicting anaerobic digester performance (2008)

Batch anaerobic digestion tests of primary sludge and waste activated sludge were conducted for a duration of 123 days to determine the ultimate degradability of the sludges. For primary sludges the inert fraction of the particulate COD that was predicted by the wastewater models could be employed to predict their biodegradability under anaerobic conditions. The degradation of waste activated sludge was adequately characterized for the first 60 days of digestion using a model that assumed equivalent biodegradability of particulate COD components under aerobic and anaerobic conditions. However after 60 days of anaerobic digestion it appeared that decay of the endogenous products was occurring. This could be described with a first order decay function with a coefficient of 0.0075 d(-1). For continuous flow digesters operating at SRTs of 30-60 days, the predicted VSS destruction with the modified model was approximately 10% higher than that predicted on the basis of inert endogenous decay products.
Faculty Opinions recommendation of Why do disordered and structured proteins behave differently in phase separation? (2019)

Intracellular membraneless organelles and their myriad cellular functions have garnered tremendous recent interest.It is becoming well accepted that they form via liquid-liquid phase separation (LLPS) of protein mixtures (often including RNA), where the organelles correspond to a protein-rich, droplet phase coexisting with a protein-poor, bulk phase.The major protein components contain disordered regions and often also RNA-binding domains, and the disordered fragments on their own easily undergo LLPS.In contrast, LLPS for structured proteins has been observed infrequently.The contrasting phase behaviors can be explained by modeling disordered and structured proteins, respectively, as polymers and colloids.These physical models also provide better understanding on the regulation of droplet formation by cellular signals and dysregulation leading to diseases.
Chronische Pankreatitis – Update (2010)

Die chronische Pankreatitis ist charakterisiert durch rezidivierende Schmerzen im mittleren Oberbauch, die in den Rücken ausstrahlen können.
Effects of Pre-annealed Nickel Contact Layer on LED Device Performance using Ni/Ag-based p-type Contacts (2013)

Effects of pre-annealed Ni contact layer on the blue LED device characteristics using Ni/Ag-based p-type contacts were investigated. It can effectively suppress reverse leakage current without affecting the forward voltage of LEDs.
Assessing Versatile Machine Learning Models for Glioma Radiogenomic Studies across Hospitals (2021)

Radiogenomics use non-invasively obtained imaging data, such as magnetic resonance imaging (MRI), to predict critical biomarkers of patients. Developing an accurate machine learning (ML) technique for MRI requires data from hundreds of patients, which cannot be gathered from any single local hospital. Hence, a model universally applicable to multiple cohorts/hospitals is required. We applied various ML and image pre-processing procedures on a glioma dataset from The Cancer Image Archive (TCIA, <i>n</i> = 159). The models that showed a high level of accuracy in predicting glioblastoma or WHO Grade II and III glioma using the TCIA dataset, were then tested for the data from the National Cancer Center Hospital, Japan (NCC, <i>n</i> = 166) whether they could maintain similar levels of high accuracy. Results: we confirmed that our ML procedure achieved a level of accuracy (AUROC = 0.904) comparable to that shown previously by the deep-learning methods using TCIA. However, when we directly applied the model to the NCC dataset, its AUROC dropped to 0.383. Introduction of standardization and dimension reduction procedures before classification without re-training improved the prediction accuracy obtained using NCC (0.804) without a loss in prediction accuracy for the TCIA dataset. Furthermore, we confirmed the same tendency in a model for IDH1/2 mutation prediction with standardization and application of dimension reduction that was also applicable to multiple hospitals. Our results demonstrated that overfitting may occur when an ML method providing the highest accuracy in a small training dataset is used for different heterogeneous data sets, and suggested a promising process for developing an ML method applicable to multiple cohorts.
Faculty Opinions recommendation of A Lamina-Associated Domain Border Governs Nuclear Lamina Interactions, Transcription, and Recombination of the Tcrb Locus. (2018)

Tcrb locus V(D)J recombination is regulated by positioning at the nuclear periphery. Here, we used DamID to profile Tcrb locus interactions with the nuclear lamina at high resolution. We identified a lamina-associated domain (LAD) border composed of several CTCF-binding elements that segregates active non-LAD from inactive LAD regions of the locus. Deletion of the LAD border causes an enhancer-dependent spread of histone H3 lysine 27 acetylation from the active recombination center into recombination center-proximal LAD chromatin. This is associated with a disruption to nuclear lamina association, increased chromatin looping to the recombination center, and increased transcription and recombination of recombination center-proximal gene segments. Our results show that a LAD and LAD border are critical components of Tcrb locus gene regulation and suggest that LAD borders may generally function to constrain the activity of nearby enhancers.
Optical Music Notes Recognition for Printed Music Score (2018)

To convert printed music score into a machine-readable format, a system that can automatically decode the symbolic image and play the music is proposed. The system takes a music score image as input, segments music symbols after preprocessing the image, then recognizes their pitch and duration. Finally, MIDI files are generated. The experiments on Rebelo Database shows that the proposed method obtains superior recognition accuracy against other methods.