gebhart/patrepeval huggingface dataset:
Teks Ucapan Naib Canselor Universiti Malaysia Perlis (UniMAP) Brig. Jeneral Dato’ Prof. Dr. Kamarudin Hussin Sempena Sambutan Aidilfitri Pusat Teknologi Komunikasi dan Pembangunan Insan 2011 (2011)

Sambutan Aidilfitri Pusat Teknologi Komunikasi dan Pembangunan Insan 2011 diadakan pada 27 September 2011.
High-resolution 3D micro-CT imaging of breast microcalcifications: a preliminary analysis (2014)

This is the first study to use micro-CT for quantitative 3D analysis of microcalcifications. This high-resolution imaging technique will be valuable for gaining a greater understanding of the morphologic characteristics of malignant and benign microcalcifications. The presence of many small microcalcifications can be an indication of malignancy. For the larger microcalcifications, 3D parameters confirmed the more irregular shape of malignant microcalcifications.
Enhanced DNA imaging using super-resolution microscopy and simultaneous single-molecule orientation measurements (2016)

Single-molecule orientation measurements provide unparalleled insight into a multitude of biological and polymeric systems. We report a simple, high-throughput technique for measuring the azimuthal orientation and rotational dynamics of single fluorescent molecules, which is compatible with localization microscopy. Our method involves modulating the polarization of an excitation laser, and analyzing the corresponding intensities emitted by single dye molecules and their modulation amplitudes. To demonstrate our approach, we use intercalating and groove-binding dyes to obtain super-resolved images of stretched DNA strands through binding-induced turn-on of fluorescence. By combining our image data with thousands of dye molecule orientation measurements, we develop a means of probing the structure of individual DNA strands, while also characterizing dye-DNA interactions. This approach may hold promise as a method for monitoring DNA conformation changes resulting from DNA-binding proteins.
Identification of an Acetoacetyl Coenzyme A Synthetase-Dependent Pathway for Utilization of l -(+)-3-Hydroxybutyrate in Sinorhizobium meliloti (2002)

D-(-)-3-Hydroxybutyrate (DHB), the immediate depolymerization product of the intracellular carbon store poly-3-hydroxybutyrate (PHB), is oxidized by the enzyme 3-hydroxybutyrate dehydrogenase to acetoacetate (AA) in the PHB degradation pathway. Externally supplied DHB can serve as a sole source of carbon and energy to support the growth of Sinorhizobium meliloti. In contrast, wild-type S. meliloti is not able to utilize the L-(+) isomer of 3-hydroxybutyrate (LHB) as a sole source of carbon and energy. In this study, we show that overexpression of the S. meliloti acsA2 gene, encoding acetoacetyl coenzyme A (acetoacetyl-CoA) synthetase, confers LHB utilization ability, and this is accompanied by novel LHB-CoA synthetase activity. Kinetics studies with the purified AcsA2 protein confirmed its ability to utilize both AA and LHB as substrates and showed that the affinity of the enzyme for LHB was clearly lower than that for AA. These results thus provide direct evidence for the LHB-CoA synthetase activity of the AcsA2 protein and demonstrate that the LHB utilization pathway in S. meliloti is AcsA2 dependent.
A mathematical model of the unfolded protein stress response reveals the decision mechanism for recovery, adaptation and apoptosis (2013)

This work contributes largely to the understanding of one of the most ubiquitous signalling pathways involved in protein folding quality control in the metazoan ER. The insights gained have direct consequences on the management of many UPR-related diseases, revealing, in addition, an extended list of candidate disease modifiers. Demonstration of stress adaptation sheds light to how preconditioning might be beneficial in manifesting the UPR outcome to prevent untimely apoptosis, and paves the way to novel approaches for the treatment of many UPR-related conditions.
Performance analysis of asynchronous optical code division multiple access with spectral‐amplitude‐coding (2014)

In this study, the performance of a spectral‐amplitude‐coding optical code division multiple access (SAC‐OCDMA) system in the asynchronous regime is evaluated using a Gaussian approximation of the decision variable for codes with fixed cross‐correlation used in SAC‐OCDMA systems. The authors consider the effect of phase‐induced intensity noise (PIIN), thermal noise and shot noise. Moreover, the validity of the Gaussian approximation is confirmed by a Kolmogorov–Smirnov fitness test. For sake of comparison, the bit error rate (BER) of the asynchronous SAC‐OCDMA system is also plotted numerically in comparison with the BER of the synchronous SAC‐OCDMA. They show that a SAC‐OCDMA system without any time management for the users, that is, the asynchronous regime, has a better performance than the synchronous SAC‐OCDMA when PIIN effect exists.
A Novel High-Yield Synthesis of Substituted Isoindolequinones (1997)

The high-yield, general, one-pot synthesis of substituted isoindolequinones, a group of important radiosensitizers which sensitize hypoxic cells to the lethal effect of radiation in cancer radiotherapy, is described. Primary amines react with 2,3-bis[2-(trimethylsilyl)ethynyl]-5,6-dimethylhydroquinone (2) in methanol at room temperature under an inert atmosphere to give substituted isoindolequinones 2-alkyl-1,3,5,6-tetramethylisoindole-4,7-quinone (4) in almost quantitative yields. Moderate yields of 4 are also obtained using 2,3-diethynyl-5,6-dimethylhydroquinone (3) and amines as reactant and solvent under the similar conditions. Tris(2-aminoethyl)amine (TREN) reacts with 2 in MeOH/THF on reflux to produce the isoindolequinone derivative of TREN. Water with 2 on reflux in MeOH forms an isobenzofuranquinone. This indicates that the formation of similar heterocycles from small molecules (e.g., Group VA and VIA hydrides) and 2 is likely. Readily synthesizable starting materials, ease of chromatographic isolation of the product, reaction generality, use of no catalyst, and cost-effective environmentally benign solvents such as MeOH/EtOH make this novel reaction simple and convenient.
Public motives and willingness to participate in first-in-human clinical trials in Saudi Arabia: A new era in the making (2019)

The Saudi public community showed a high level of enthusiasm for participation in future FIH clinical trials, yet they had some reservations. Increasing public awareness about the benefits of clinical trials and conduction process helps to alleviate the concerns of the Saudi people and to increase their likelihood of enrollment.
Flow Regimes in Transverse Rectangular Cavities. (1965)

Pressure measurement in rectangular cavities on body side compared with wind tunnel wall cavities measurement having similar length-to-height ratios
Hybrid reactive power compensation system: advanced control strategy development (2004)

Electric arc furnaces are a major cause of line disturbance problems, in terms of flickers and of harmonic pollution. Various solutions had been proposed and applied, with the aim to compensate or control line disturbance phenomena. Optimal solutions can be found by using series and shunt devices, but system cost, reliability and efficiency become main issues. In the paper, authors propose a hybrid control and compensation system that allows an optimal tradeoff in performance and system cost, while providing high efficiency and reliability. The solution is a thyristor based series controller coupled with a high performance shunt compensator. The use of phase control thyristor and the fast changing characteristics of furnace load impose the development of an open loop advanced control strategy based on a load estimator and on the prediction of instantaneous active and reactive power associated with partialized waveforms. Power associated with harmonics is also computed on line, in order to achieve better performances under extreme load conditions and in order to minimize the power required by the expensive shunt compensator. Concept effectiveness is shown by extensive computer simulations.
PRIVILEGIA CONCESSA ET CONFIRMATA, REGNANTE WILLELMO CONQUESTORE (2012)

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Acute Kidney Injury in Cardiogenic Shock: Definitions, Incidence, Haemodynamic Alterations, and Mortality (2017)

Abstract Aims To investigate the incidence, haemodynamic alterations and 90-day mortality of acute kidney injury (AKI) in patients with cardiogenic shock. We assessed the utility of creatinine, urine output (UO) and cystatin C (CysC) definitions of AKI in prognostication. Methods and results Cardiogenic shock patients with serial plasma samples (n = 154) from the prospective multicenter CardShock study were included in the analysis. Acute kidney injury was defined and staged according to the KDIGO criteria by creatinine (AKIcrea) and/or UO (AKIUO). CysC-based AKI (AKICysC) was defined similarly to AKIcrea. Changes in haemodynamic parameters were assessed over time from baseline until 96 h. Mean age of the study population was 66 ± 12 years and 74% were men. Median baseline creatinine was 1.12 [interquartile range (IQR) 0.87–1.54] mg/dL and CysC 1.19 (IQR 0.90–1.69) mg/L. The 90-day mortality was 38%. The incidences for AKI were: AKIcrea 31%, AKIUO 50%, and AKICysc 33%. AKIcrea [odds ratio (OR) 12.2, 95% confidence interval (CI) 4.1–36.0] and AKICysC (OR 2.5, 95% CI 1.1–6.1), but not AKIUO, were independent predictors of mortality. However, a stricter UO cut-off of &amp;lt;0.3 mL/kg/h for 6 h was independently associated with 90-day mortality (OR 3.6, 95% CI 1.4–9.3). Development of AKI was associated with persistently elevated central venous pressure and decreased cardiac index and mean arterial pressure. Conclusions Acute kidney injury is frequent in patients with cardiogenic shock and especially AKIcrea predicts poor outcome. The KDIGO UO criterion seems, however, rather liberal and a stricter AKI definition of UO &amp;lt;0.3 mL/kg/h for at least 6 h seems more useful for mortality risk prediction. Haemodynamic alterations reflecting venous congestion and hypoperfusion were associated with AKI.
Microseismic Monitoring of Hydraulic Fracturing - Physical Fundamentals of Interpretation (2006)

Several basic dynamic processes related to propagation of hydraulic fracturing modify the effective stress in rocks and, therefore, they are relevant for triggering of microseismicity. For instance, these are the creation of the new fracture volume, fracturing fluid loss and its infiltration into reservoir rocks as well as diffusion of the injection pressure into the pore space of surrounding rocks and inside the fracture. Here, using real data we show these processes can be seen from features of the spatio-temporal distributions of the induced microseismicity. Especially, the initial stage of the fracture volume opening as well as the back front of the induced seismicity starting to propagate after termination of the fluid injection can be well identified and used for reservoir engineering.
Oscillator and Filter Algorithms for Virtual Analog Synthesis (2006)

June 01 2006 Oscillator and Filter Algorithms for Virtual Analog Synthesis Vesa Välimäki, Vesa Välimäki Search for other works by this author on: This Site Google Scholar Antti Huovilainen Antti Huovilainen Search for other works by this author on: This Site Google Scholar Author and Article Information Vesa Välimäki Antti Huovilainen Online ISSN: 1531-5169 Print ISSN: 0148-9267 © 2006 Massachusetts Institute of Technology2006 Computer Music Journal (2006) 30 (2): 19–31. https://doi.org/10.1162/comj.2006.30.2.19 Cite Icon Cite Permissions Share Icon Share Facebook Twitter LinkedIn MailTo Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Search Site Citation Vesa Välimäki, Antti Huovilainen; Oscillator and Filter Algorithms for Virtual Analog Synthesis. Computer Music Journal 2006; 30 (2): 19–31. doi: https://doi.org/10.1162/comj.2006.30.2.19 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsComputer Music Journal Search Advanced Search This content is only available as a PDF. © 2006 Massachusetts Institute of Technology2006 Article PDF first page preview Close Modal You do not currently have access to this content.
The Return of the Vulnerable Plaque: Optical Coherence Tomography Imaging of a Case of a Late In-Stent Restenotic Chronic Total Occlusion (2016)

Although the use of drug-eluting stents (DES) has dramatically decreased the incidence of in-stent restenosis (ISR), concerns regarding the late manifestations of ISR remain. Optical coherence tomography (OCT) imaging provides unique insights into characteristics and patterns of ISR. We report a case of late DES ISR with unusual heterogeneous intracoronary luminal characteristics suggestive of vulnerable atherosclerotic plaque activity by OCT imaging. This case demonstrates that late ISR after DES may involve more than mere neointimal hyperplasia with lesion-associated craters, septae, and neoatherosclerosis. The use of OCT provides novel insights into the mechanisms and potential biology of the late DES ISR.
Optical non-linearity in liquid crystals using surface plasmon-polaritons (1989)

The authors present a detailed report of the observation of a strong, thermally induced optical non-linearity in a system comprised of a silver film and a nematic liquid crystal, in which the surface plasmon-polariton (SPP) mode may be excited. Various measurements of the reflected intensity from the experimental system as a function of the incident angle, including a novel 'AC-on-DC' probe technique, reveal that the observed sharp optical switching is due to warming of liquid crystal, close to the metal/liquid crystal interface, into the isotropic phase through loss of energy of SPPS in Joule heating of the silver film. The many factors contributing to the observed reflectances are investigated and lead to a detailed model of the non-linearity for which a computer model is constructed. Conclusions drawn from the results of this work have serious implications for the use of SPPS in non-linear optics.
Nitrogen‐Doped Graphene/Carbon Nanotube Hybrids: In Situ Formation on Bifunctional Catalysts and Their Superior Electrocatalytic Activity for Oxygen Evolution/Reduction Reaction (2014)

There is a growing interest in oxygen electrode catalysts for oxygen reduction reaction (ORR) and oxygen evolution reaction (OER), as they play a key role in a wide range of renewable energy technologies such as fuel cells, metal‐air batteries, and water splitting. Nevertheless, the development of highly‐active bifunctional catalysts at low cost for both ORR and OER still remains a huge challenge. Herein, we report a new N‐doped graphene/single‐walled carbon nanotube (SWCNT) hybrid (NGSH) material as an efficient noble‐metal‐free bifunctional electrocatalyst for both ORR and OER. NGSHs were fabricated by in situ doping during chemical vapor deposition growth on layered double hydroxide derived bifunctional catalysts. Our one‐step approach not only provides simultaneous growth of graphene and SWCNTs, leading to the formation of three dimensional interconnected network, but also brings the intrinsic dispersion of graphene and carbon nanotubes and the dispersion of N‐containing functional groups within a highly conductive scaffold. Thus, the NGSHs possess a large specific surface area of 812.9 m 2 g −1 and high electrical conductivity of 53.8 S cm −1 . Despite of relatively low nitrogen content (0.53 at%), the NGSHs demonstrate a high ORR activity, much superior to two constituent components and even comparable to the commercial 20 wt% Pt/C catalysts with much better durability and resistance to crossover effect. The same hybrid material also presents high catalytic activity towards OER, rendering them high‐performance cheap catalysts for both ORR and OER. Our result opens up new avenues for energy conversion technologies based on earth‐abundant, scalable, noble‐metal‐free catalysts.
ChemInform Abstract: Total Syntheses of Fungal Metabolites and Functionalized Furanones. (1986)

Abstract Die fungalen Metaboliten Colletochlorin D (Ib), (i)‐Ascofuranon (Ic) und dessen Stereoisomeres (Id) sowie das aus den Blättern von Geigera parviflora Lindl isolierte Geiparvarin (II) werden gemäß der im Schema angegebenen Synthesesequenzen hergestellt.
Molecular Aspects of Osmotic Stress in Plants (1997)

Abstract Plant molecular responses to osmotic stress are complex as evidenced by the isolation of numerous OR (osmotic stress-regulated) genes. Although functions including osmolyte biosynthesis, membrane transport, signal transduction, and cellular protection have been predicted for OR genes, few of them have been established. Current efforts toward isolating and analyzing the expression of individual OR genes should be replaced by systematic approaches to analyze all OR genes simultaneously in selected plant species. Both transcriptional and posttranscriptional regulation of OR genes have been described. Cis-elements that respond to osmotic stress through abscisic acid (ABA)-dependent as well as ABA-independent pathways have been identified. Functional genetic approaches using yeast and plant model systems are expected to complement current molecular analysis of overexpression of OR genes in transgenic plants. These systems will help to establish functions of OR genes, to dissect osmotic stress-signaling pathways, and to determine critical and rate-limiting cellular processes for osmotic stress tolerance. In this regard, initial results obtained through mutational analysis in Arabidopsis thaliana are promising and have identified novel salt-tolerant as well as salt-hypersensitive mutants.
Results of orthotopic heart transplantation for ischaemic cardiomyopathy (1987)

From July 1983 to May 1987, 172 orthotopic heart transplantations were performed in 165 patients. Of these, 46 recipients (39 male, 7 female), aged between 26 and 56 years (mean age 47), suffered from ischaemic cardiomyopathy. Postoperative immunosuppression consisted of a triple drug regimen of cyclosporine A, azathioprine and, in the last 31 patients, low-dose steroids. The actuarial survival in this group of patients at 1 year and at 2 years was 71.9%. There were five early deaths: three due to acute rejection and two from multiple-organ failure and sepsis. Of the eight late deaths, two could be attributed to acute cardiac rejection and four to bacterial infections. In two patients, sudden death occurred in the presence of accelerated graft atherosclerosis. Mild-to-moderate coronary artery lesions were seen in five other patients undergoing angiography one year after transplantation. Apart from the well-known postoperative risk factors in cardiac transplant recipients, accelerated graft atherosclerosis appears to be an additional hazard in the subgroup surgically treated for ischaemic cardiomyopathy.
The Endocrinology of Resistance Exercise and Training (2009)

Resistance exercise elicits an array of hormonal responses critical to acute muscular force and power production as well as subsequent tissue growth and remodeling. In general, the acute response is dependent upon the stimulus and may be the most critical element to tissue remodeling. Thus, modifications of training intensity, volume (or total work), muscle mass involvement, rest intervals, and frequency can impact the acute hormonal response. Long-term adaptations in neuroendocrine function seem minimal but may be related to the current intensity/volume of the training stimulus. The significance of these hormonal responses is not entirely known. For the sports nutritionist, the effect of various nutritional/supplemental strategies can indeed have an effect on the hormonal milieu. For instance, the timing of supplementation/feeding pre- and postexercise may affect the endocrine response to resistance exercise. Also, the consumption of various macronutrients can impact the basal concentration of various hormones.
A Novel Concept of a Dual-Orthogonal Polarized Ultra Wideband Antenna for Medical Applications (2009)

This paper describes a concept of a dual-orthogonal, linearly polarized ultra wideband (UWB) antenna. The radiation principle and feeding scheme is described. Subsequently the prototype is introduced and the theoretical assumptions are verified by the measurements. A very good polarization purity was achieved over very wide frequency range.
A Principled Approach to Developing New Languages for Live Coding (2011)

This paper introduces Improcess, a novel cross-disciplinary collaborative project focussed on the design and development of tools to structure the communication between performer and musical process. We describe a 3-tiered architecture centering around the notion of a Common Music Runtime, a shared platform on top of which inter-operating client interfaces may be combined to form new musical instruments. This approach allows hardware devices such as the monome to act as an extended hardware interface with the same power to initiate and control musical processes as a bespoke programming language. Finally, we reect on the structure of the collaborative project itself, which offers an opportunity to discuss general research strategy for conducting highly sophisticated technical research within a performing arts environment such as the development of a personal regime of preparation for performance.
Matrix product states: Symmetries and two-body Hamiltonians (2009)

We characterize the conditions under which a translationally invariant matrix product state (MPS) is invariant under local transformations. This allows us to relate the symmetry group of a given state to the symmetry group of a simple tensor. We exploit this result in order to prove and extend a version of the Lieb-Schultz-Mattis theorem, one of the basic results in many-body physics, in the context of MPS. We illustrate the results with an exhaustive search of SU(2)-invariant two-body Hamiltonians which have such MPS as exact ground states or excitations.
Privacy Negotiation in Socio-Technical Systems (2012)

A socio-technical system (STS) is an approach to complex organizational work design that recognizes the interaction between people and technology in workplaces. The term also refers to the interaction between society’s complex infra-structures and human behavior. In this sense, society itself, and most of its substructures, are complex socio-technical systems. This paper addresses a class of socio-technical systems, represented by web services in a number of domains and attempts to understand the possibility of empowering the web users and consumers to have a say in the develop-ment of privacy agreements. This paper examines the likelihood of the web users and consumers leveraging such a capability, should it exist. This should improve the way privacy agreements are handled that benefits both the service providers and the web users.