gebhart/patrepeval huggingface dataset:
Mitogenic potency of insulin glargine. (2009)

The goal of diabetes mellitus treatment is to maintain long-term near-normoglycaemia to prevent the onset or progression of long-term complications. In order to achieve tight glycaemic control and improve the quality of life for diabetic patients, a number of novel insulin preparations, insulin analogues, have been constructed thanks to recombinant DNA technologies and advanced protein chemistry. Because structurally modified insulins may differ from human insulin not only in metabolic but also in mitogenic potencies there were concerns raised about the possibility of increased insulin analogue proliferative action or tumourigenesis. In vitro and in vivo studies on insulin analogues in comparison to endogenous insulin have been performed to closely monitor the insulin analogue action profiles. Insulin glargine was the only one presenting a significant increase in affinity to insulin-like growth factor type 1 (IGF-1) receptor. However, there was controversy regarding the safety of insulin glargine use because of its potential risk of mitogenicity but it proved to be true only for human osteosarcoma cells Saos/B10. Outcomes of the studies performed on lines other than cancer cells and on animals did not present any increased mitogenic activity nor mitogenic potency of insulin glargine in comparison to human insulin.
VARIATION IN THE GROUP-SPECIFIC CARBOHYDRATE OF GROUP A STREPTOCOCCI (1955)

The phenomenon of apparent loss of group-specific carbohydrate in the course of mouse passage of group A streptococci has been subjected to further study, and several additional variants showing this property have been described. The loss of group reactivity is shown to be due to an alteration in the chemical structure and serological specificity of the cell wall carbohydrate. This alteration appears to be essentially the same in each of the variants available for study. The carbohydrate of the variant strains (V) contains the same two monosaccharide components as the group A carbohydrate (A), but they are present in different proportions. Precipitating sera reactive with V carbohydrate have been prepared, and the A and V carbohydrates have been compared by qualitative and quantitative precipitin analysis. A second type of variation has been encountered during mouse passage. This variation is characterized by the occurrence of a cell wall carbohydrate (I) intermediate in chemical and serological properties between the A and V carbohydrates. The I carbohydrate reacts with both A and V antisera and does not appear to be a simple mixture of A and V carbohydrate. Similarly, antisera against the intermediate strain contain antibodies reactive with both A and V carbohydrates, and evidence is presented indicating that in part this represents antibody with double specificity.
Ab initiopseudopotential description of cohesion in NaCl (1982)

We present the first ab initio pseudopotential calculation of the cohesive properties of NaCl. The theoretical results for the equilibrium lattice constant and the bulk modulus are in good agreement with experiment. Our physical picture of cohesion is contrasted to that of widely used models.
Performance Evaluation of Motion Tracking Methods: Magnetic Induction and HF RFID (2022)

Human motion tracking has broad applicability, and currently, various approaches are available for its deployment. Wearable sensors and vision-based methods are among the most commonly used techniques that still face challenges in terms of accuracy, privacy, coverage, and cost. The magnetic induction (MI) system is a new approach based on inductive coupling, representing motions via variation in the MI signals. In this work, we present the performance analysis of the MI system and compare its accuracy with a high frequency (HF) radio frequency identification (RFID) system using experimental measurements in 3D motion tracking.
PLS loading scatter plot with being in the EF or SF group as dependent variables. (2017)

&lt;p&gt;The model included genera and species/phylotypes identified by HOMD blasting after exclusion of OTUs with &lt;15 sequences, sex, mode of delivery, anthropometric measures, and lactobacilli by culture as the independent block. w describes the PLS weights from the combination of the original variables in the X-swarm and c the same for the Y-swarm. Taxa with a statistically significant PLS correlation coefficient ≥0.1 are indicated. * after a taxa denotes that the corresponding genus was influential. For full list and univariate p-values see &lt;a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0169831#pone.0169831.s004" target="_blank"&gt;S1&lt;/a&gt; and &lt;a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0169831#pone.0169831.s005" target="_blank"&gt;S2&lt;/a&gt; Tables.&lt;/p&gt;
Is epidermal cell proliferation in psoriatic skin grafts on nude mice driven by T-cell derived cytokines? (1992)

Plasminogen activity and DNA synthesis by epidermal cells have been reported to be doubled in psoriatic skin grafts compared with grafts of normal skin 6 weeks after transplantation to nude mice. In our study human lymphocytes disappeared from such grafts within 48 h whilst some DR-positive human dendritic cells were retained in the grafts for up to 4 weeks. However, the grafts were infiltrated by Thy 1.2+ mouse lymphocytes within 6 days and this infiltration persisted at a moderate level throughout the observation period. It consisted of perivascular aggregates, scattered dermal and papillary T cells, and some mouse T cells were also found in the epidermal compartment. Grafts of psoriatic and non-psoriatic control skin were infiltrated to a similar extent, suggesting a low-grade rejection response against the human xenografts. These findings raise the possibility that psoriatic keratinocytes are responding abnormally to inflammatory cytokines released by mouse lymphocytes reacting against the skin grafts.
A Laboratory-Built Fully Automated Ultrasonication Robot for Filamentous Fungi Homogenization (2019)

This article presents the design and development of a new hands-free ultrasonication robot for filamentous fungi homogenization. The platform was constructed with a modified inexpensive 3D printer, equipped with an upward-facing camera, a custom-designed wash station, and an add-on sonicator. While machine vision accomplished sample well screening based on image subtraction and color thresholding, it also determined the level of fungi homogeneity using color variance. Model fitting reveals that the process of filamentous fungi homogenization using ultrasonication included a period of significant exponential decay. Therefore, this procedure allowed for the rapid homogenization of the fungal samples during the initial stages of ultrasonication treatment followed by a deceleration in homogenization. Furthermore, a factorial experiment showed that higher sonicator power and temperature accelerated the homogenization process, while the cultivation time exhibited no effect on homogenization. In addition, the model parameters were varied between the wells, even when subjected to the same settings, meaning that the system cannot use the same asymptote of the homogeneity level to establish the termination time for different wells. Therefore, we used the standard deviation of the four most recent homogeneity level values to determine the termination time. This method was used for feedback control, forming a fully automated robot that did not require manual intervention during the experiment. A validation test on filamentous fungi demonstrated that the system was able to provide target quality of samples efficiently.
Vehicle Motion Control under Limit State and Fastest Speed Control by Using Nonlinear Model Predictive Control (2017)

In this paper, we propose a vehicle motion control method considering stability at the limit state using nonlinear model predictive control. In order to consider the vehicle limit state, a vehicle model is defined by using a nonlinear tire model that considers combined slip etc. The steering angle and the slip rates of each wheel at the limit lateral acceleration state are calculated on the numerical simulations. In addition, as an application example of the proposed method, results of running a circuit course at the fastest speed using curvature minimum path generation algorithm is demonstrated. Simulation results show that the proposed method can run at the speed at the lateral acceleration limit according to the course shape and it is able to run on the out-in-out trajectory.
Meliniomyces, a new anamorph genus for root-associated fungi with phylogenetic affinities to Rhizoscyphus ericae (≡ Hymenoscyphus ericae), Leotiomycetes (2005)

Abstract Sterile fungi isolated from surface-sterilized roots of the Ericaceae, and hypothesized to be conspecific based primarily on restriction fragment length polymorphisms, were provisionally named as Variable White Taxon (VWT). In preliminary resynthesis trials with Vaccinium myrtilloides or V. vitis-idaea, isolates did not form typical ericoid mycorrhizas. Additional isolates obtained from roots of the Orchidaceae, Pinaceae, Betulaceae and Salicaceae, and given informal names such as Sterile white 1 (SW1), were thought to represent the same taxon based on cultural similarities. To evaluate conspecificity and infer phylogenetic affinities, partial nuclear ribosomal DNA sequences were determined. Parsimony analyses supported a species level distinction for VWT/SW1 and indicated that the fungus is placed within the species complex referred to as the “ Hymenoscyphus ericae aggregate” which includes H. ericae ( Leotiomycetes ), many unnamed taxa and Cadophora finlandica. The new genus and species Meliniomyces variabilis is proposed to accommodate this root-associated fungus to facilitate discussion and information retrieval, and to provide a foundation for additional experimental work. Although isolates are sterile in culture, they can be identified by morphological characters in conjunction with ribosomal internal transcribed spacer (ITS) sequence data. The mycorrhizal status of M. variabilis is not yet clear. In prior published results, strains demonstrated no or some colonization with ericoid and ectomycorrhizal hosts but did not form true ectomycorrhizas. ITS analyses indicated that the “ H. ericae aggregate” includes several other well-supported clades putatively named as Meliniomyces species. Representative strains were examined morphologically for two of these species, described as M. vraolstadiae and M. bicolor. Both include ectomycorrhizal mycobionts of the “ Piceirhiza bicolorata ” morphotype. Rhizoscyphus ericae is accepted as the appropriate name for H. ericae. Taxonomic novelties: Meliniomyces Hambleton & Sigler anam. gen. nov., Meliniomyces variabilis Hambleton & Sigler sp. nov., Meliniomyces bicolor Hambleton & Sigler sp. nov., Meliniomyces vraolstadiae Hambleton & Sigler sp. nov.
20-Mw combined cycle will burn sewage sludge gas (1979)

An in-house powerplant for sewage treatment facility, which will run on low-Btu gas, is expected to save the Los Angeles County sanitation district some $10,000 per day in continuous duty service and will deliver close to 60% efficiency in total energy model of operation.
A tunable CMOS-DRAM voltage limiter with stabilized feedback amplifier (1990)

The authors present two developments for DRAM voltage limiters: a precise internal-voltage generator composed of a PMOS threshold-voltage-difference generator and a tunable voltage-up converter with fuse trimming; and a stabilized driver composed of a feedback amplifier with compensation for a time-dependent load. These circuits provide a voltage not susceptible to the supply-voltage and substrate-voltage bouncings, temperature variation, and threshold-voltage deviation due to the process fluctuation, while maintaining CMOS-DRAM process compatibility. Moreover, feedback-loop stability and frequency response are maintained by ensuring a phase margin of 55° at a unity-gain frequency of 10 MHz using compensation through zero insertion. Implementation of these new circuits in a 16-Mb CMOS DRAM is reported
Structural and Immunological Characteristics of Chronically Inflamed Adenotonsillar Tissue in Childhood (2004)

Recurrent or chronic adenotonsillar infections mainly affect children and frequently involve otherwise healthy subjects. Therefore, having excluded systemic immunological deficiencies, this disease may be due to a local dysfunction of the epithelial structures at either the rhino or oropharyngeal level. The aim of the present investigation was to analyze structural and immunological aspects of tonsils and adenoids in subjects who underwent adenotonsillectomy because of recurrent inflammatory episodes with fever. Histological studies and analyses of the cytokine patterns were carried out in palatine tonsils and adenoid samples from 105 patients who underwent adenoidectomy and bilateral extracapsular tonsillectomy for chronic inflammatory hypertrophy of these organs; 46 of the 105 cases examined presented hyperkeratosis of the crypt epithelium; in the remaining 59, the epithelium was hyperplastic with no signs of keratosis. Scanning electron microscopy revealed a continuous epithelial surface of polygon-shaped flattened cells with fissures towards the cryptic depressions. Titration of interleukin-1beta and tumor necrosis factor alpha in serum and tissues demonstrated higher concentrations in the adenotonsillar specimens, whereas the rise in interleukin-6 was more modest.
Controlled Electrodeposition and Magnetic Properties of Co35Fe65Nanowires with High Saturation Magnetization (2016)

Among all transition metals magnetic alloys, Co35Fe65 possesses the highest saturation magnetization BS = 2.45 T at room temperature given by the so-called "Slater-Pauling limit". For controlled electrodeposition of Co35Fe65 nanowire arrays the following parameters were found to be optimal: electrolyte solution with 1–2 mM malonic acid (MA), ionic ratio Fe+2/Co+2 = 2.0, growth rate, and pulsed potential deposition with time-on (2.5 s) at the potential of −1.15 V/SCE and time-off (1.0 s) at −0.70 V/SCE. These arrays were deposited inside anodic aluminum oxide (AAO) templates that contained columnar nanopores with diameters either 35 or 200 nm. Cyclic voltammetry was used in solution with and without MA and reaction mechanism was proposed to explain the critical role of MA in electrodeposition of CoFe alloys. In addition to uniform deposition of stechiometric Co35Fe65 alloys, a selectivity ratio, (SR) ∼1.0, were achieved, which means that the atomic ratio of Fe/Co in the nanowire matched the molar ratio of Fe+2/Co+2 in the electrolyte. The magnetic behavior of the subsequent 2.45 T Co35Fe65 nanowire arrays showed that the shape and magnetostatic anisotropies dominated the effective anisotropy, and the impact of magnetocrystalline and magnetelastic anisotropies field was very small.
An atherogenic lipid profile with low serum paraoxonase‐1 activity during nematode infection in rats (2010)

Nippostrongylus brasiliensis infection can induce atherogenic lipid profile and reduce serum PON1 activity.
SIS0NIC - THE FIRST COMMERCIALIZED MEMS MICROPHONE (2006)

The Knowles SiSonic TM MEMS microphone has been successfully commercialized for use in cell phones, cameras, PDA's, and other high volume consumer electronics. One advantage that MEMS microphones have over traditional Electret Condenser Microphones (ECMs) is the ability to be reflow soldered. Cost is a significant driver in the design of a MEMS microphone. SiSonic TM uses a non-integrated approach to MEMS and CMOS while minimizing both die sizes. Key to the small MEMS die size is the use of a simply supported freeplate diaphragm. The CMOS die has been optimized to work with very low input capacitance. A low cost package has been developed utilizing laminated FR4 PCB material. The microphones are 100% tested on a high speed automated acoustic test station.
Deep Oxidation of Fluorinated Hydrocarbons in Molten Catalysts (2003)

The oxidation of fluorine-containing organic substances: fluorocarbon liquid M-1, fluorinated alcohol H(CF2)8CH2OH, and powder polytetrafluoroethylene with air has been studied in melts: NaOH; 43 mol.% LiCl В - 33 mol.% NaCl - 24 mol.% KCl (eutectic mixture); (LiCl-NaCl-KCl)eutec. + 10 mass.% V2O5; (LiCl-NaCl-KCl) eutec. + 15 mass.% V2O5; 56 mol.% Na2CO3 - 44 mol.% K2CO3 (eutectic), (Na2CO3 K2CO3)eutect. + 15 mass.% V2O5, and K3V5O14. The compositions of the melts have been examined by GC, DTA, chemical analysis and XRD, and they have been shown to change during the reaction, depending on the composition and partial pressure of the gaseous products over the melt surface. The alkali metal chloride melt containing 15 mass.% V2O5 has been found to be most stable to the action of fluorine compounds. Possibility of deep oxidation of fluorine-containing organic substances in melts based on hydroxides, carbonates and chlorides of alkali metals doped with oxides of vanadium has been proved. The process of deep oxidation of fluorinated hydrocarbons is accompanied by formation of an equilibrium mixture containing hydroxides, carbonates, chlorides and fluorides of alkali metals, as well as their vanadates, if V2O5 additive is used. The relative amounts of these substances in molten systems are determined by the partial pressure of oxygen, CO2 and water vapor.
Networking low-power energy harvesting devices: Measurements and algorithms (2011)

Recent advances in energy harvesting materials and ultra-low-power communications will soon enable the realization of networks composed of energy harvesting devices. These devices will operate using very low ambient energy, such as indoor light energy. We focus on characterizing the energy availability in indoor environments and on developing energy allocation algorithms for energy harvesting devices. First, we present results of our long-term indoor radiant energy measurements, which provide important inputs required for algorithm and system design (e.g., determining the required battery sizes). Then, we focus on algorithm development, which requires nontraditional approaches, since energy harvesting shifts the nature of energy-aware protocols from minimizing energy expenditure to optimizing it. Moreover, in many cases, different energy storage types (rechargeable battery and a capacitor) require different algorithms. We develop algorithms for determining time fair energy allocation in systems with predictable energy inputs, as well as in systems where energy inputs are stochastic.
A resource management framework for priority-based physical-memory allocation (2002)

Most multitasking operating systems support scheduling priorities in order to ensure that processor time is allocated to important or time-critical processes in preference to less important ones. Ideally this would prevent a low-priority process from slowing the execution of a high-priority one. In practice, strict prioritisation is undermined by a lack of suitable allocation policy for resources other than CPU time. For example, a low priority process may degrade the execution speed of a high-priority process by competing with it for physical memory. We present the design of a flexible resource management framework which prioritises memory allocation, and examine a prototype implementation for the Mungi single-address-space operating system.
Non-Linear Steady-State Electrical Current Modeling for the Electropermeabilization of Biological Tissue (2015)

We propose a non-linear steady-state model of irreversible electropermeabilization in a biological tissue. The non-linear problem is solved using a modified fixed point iteration. The unknown parameters are experimentally estimated from the observation of the necrosis on a potato tissue for different applied voltages. A variability study of the parameters involved in the model is performed.
Validity of the high temperature approximation and influence of polydispersity on the phase separation in charged colloidal dispersions (1985)

A recent perturbation calculation predicting a ‘liquid-gas’ phase separation of charge-stabilized colloidal suspensions is tested against the thermodynamically self-consistent generalized mean spherical approximation. A comparison between the two calculations shows that the perturbation calculation predicts a reasonably accurate critical temperature, but overestimates the critical density. These critical parameters are moreover shown to be rather insensitive to moderate degrees of polydispersity.
A tree structured Bayesian scalar quantizer for wavelet based image compression (2002)

Multiresolution image decompositions (e.g., wavelets), in conjunction with a variety of quantization schemes, have been shown to be very effective for image compression. Recently, several promising tree-structured quantization schemes that exploit the correlation across scales have been proposed. In this paper, we present an image compression algorithm based on a multiresolution Markov random field model used to model the correlations of wavelet coefficients across the scales. We also present experimental results obtained using the algorithm.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
The new Siemens gas turbine SGT5-8000H for more customer benefit (2007)

E.ON Energy and Siemens are implementing a new power plant project in Irsching in Bavaria which will set new benchmarks as far as efficiency and cost-effectiveness are concerned. With 340 MW, the gas turbine installed will be the largest and most efficient in the world. After the test phase, this gas turbine plant will be expanded to become a highly efficient CCGT plant with an output of around 530 MW and an efficiency of over 60 per cent. (orig.)