gebhart/patrepeval huggingface dataset:
Isolation of the tomato AGAMOUS gene TAG1 and analysis of its homeotic role in transgenic plants. (1994)

To understand the details of the homeotic systems that govern flower development in tomato and to establish the ground rules for the judicious manipulation of this floral system, we have isolated the tomato AGAMOUS gene, designated TAG1, and examined its developmental role in antisense and sense transgenic plants. The AGAMOUS gene of Arabidopsis is necessary for the proper development of stamens and carpels and the prevention of indeterminate growth of the floral meristem. Early in flower development, TAG1 RNA accumulates uniformly in the cells fated to differentiate into stamens and carpels and later becomes restricted to specific cell types within these organs. Transgenic plants that express TAG1 antisense RNA display homeotic conversion of third whorl stamens into petaloid organs and the replacement of fourth whorl carpels with pseudocarpels bearing indeterminate floral meristems with nested perianth flowers. A complementary phenotype was observed in transgenic plants expressing the TAG1 sense RNA in that first whorl sepals were converted into mature pericarpic leaves and sterile stamens replaced the second whorl petals.
Influence of Storage on the Composition of Clarified Apple Juice Concentrate (1986)

ABSTRACT The effect of storage on apple juice concentrate was determined by following changes in composition during a period of 111 days at 37°C. Results showed that storage caused an 87% loss in the total free amino acids, which was mostly due to decreases in glutamic acid, asparagine and aspartic acid. The forml titration method was inadequate for determining the amino compounds involved in Maillard‐type reactions. Sucrose was hydrolyzed under these conditions at a rate corresponding to a fist order process. The reducing sugars increased at a rate determined by the inversion of sucrose; no consumption attributable to browning reaction was detected. Reduction of organic acids was 9% while apparent phenolic compounds increased from 0.149 to 0.215 g/100g. A maximum accumulation of HMF was observed after 100 days of storage.
The thin layer chromatography of vat dyes (1992)

The identification and separation of vat dyes by thin layer chromatography has been investigated with reducing and non‐reducing systems. The results showed that the chromatograms on silica gel plates obtained by non‐reducing systems at 100 or 120°C were fast, reproducible and easy to control. Nine non‐reducing eluents were developed, producing good migration and resolution of 21 vat dyes. Analyses of the chromatograms revealed that the R f , values varied with the temperature of the system, the chemical structure of the vat dyes and the nature of adsorbent, as well as with the eluents used. The effects of molecular masses of the vat dyes on the R f values were less significant. Despite the successful use of a novel reducing agent for vat dyes, the chromatography of reduced dye was largely unsatisfactory. The use of reversed‐phase t.l.c. plates was examined and showed little benefit.
Irregular three-coordination in mercury: structures of phenyl- and methylmercury(II) dithizonate (1980)

[Hg(C6Hs)(CI3HIlN4S)] crystallizes in the monoclinic space group P2Jc with a = 5.991 (3), b = 20.68 (1), c = 17.129 (9) A,/~= 99.40 (5) °, Z = 4. [Hg(CH3)(CI3HIIN4S)] crystallizes in the triclinic space group Pl with a = 14.866 (7), b = 11.194 (6), c = 4.557 (3) A, a = 89.30 (5),/~= 95.85 (5), y= 97.62 (5) °, Z = 2. Final R = 0.058 and 0.061 respectively. In both structures the Hg atom exhibits planar, irregular three-coordination, the geometry at the Hg atom being approximately T-shaped, with the dithizone residue (C 13HllN4S-) acting as a bidentate ligand coordinating through S and N. The imino proton participates in a weak intramolecular hydrogen bond which stabilizes the N-N-C-N-N chain in an anti,s-trans configuration relative to the formal C=N double and C-N single bonds.
IBEM applied to the design of gradient coils for superconducting MRI (2015)

This paper proposes an efficient design method for designing MRI gradient coils on a cylindrical surface geometry, using an inverse boundary element method (IBEM). Based on the approximate current density over the whole coils space, the magnetic field distribution can be obtained in the discrete form. An objective function is found to evaluate the minimum error between actual magnetic field that coils generate and desired magnetic field. Finally, the current distribution is transformed to the winding pattern of gradients via the relationship between current and stream function. This method can be used for coils on arbitrary surface shapes. The design examples of x-gradient coil, z-gradient are shown to demonstrate such method is more efficient and versatile to apply to the design of coils. Such method can also be used to design shim coils.
Voice coil bobbin connection to loudspeaker diaphragm of honeycomb core sandwiched by sheets (1982)

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Crustacean Color-Change Hormone: Amino Acid Sequence and Chemical Synthesis (1972)

The blanching hormone of the prawn, Pandalus borealis, is pGlu-Leu-Asn-Phe-Ser-Pro-Gly-Trp-NH(2). Its structure was settled by a combination of mass spectrometry and Edman-dansyl analysis of a thermolysin fragment. Confirmation of the structure was obtained by chemical synthesis from amino acids. This neurosecreted hormone is active in picogram amounts when tested in shrimps.
The uniqueness of flow in probing the aggregation behavior of clinically relevant antibodies (2020)

The development of therapeutic monoclonal antibodies (mAbs) can be hindered by their tendency to aggregate throughout their lifetime, which can illicit immunogenic responses and render mAb manufacturing unfeasible. Consequently, there is a need to identify mAbs with desirable thermodynamic stability, solubility, and lack of self-association. These behaviors are assessed using an array of in silico and in vitro assays, as no single assay can predict aggregation and developability. We have developed an extensional and shear flow device (EFD), which subjects proteins to defined hydrodynamic forces which mimic those experienced in bioprocessing. Here, we utilize the EFD to explore the aggregation propensity of 33 IgG1 mAbs, whose variable domains are derived from clinical antibodies. Using submilligram quantities of material per replicate, wide-ranging EFD-induced aggregation (9-81% protein in pellet) was observed for these mAbs, highlighting the EFD as a sensitive method to assess aggregation propensity. By comparing the EFD-induced aggregation data to those obtained previously from 12 other biophysical assays, we show that the EFD provides distinct information compared with current measures of adverse biophysical behavior. Assessing a candidate's liability to hydrodynamic force thus adds novel insight into the rational selection of developable mAbs that complements other assays.
MODELO DE JOGO E PROCESSO DE ENSINO NO FUTEBOL: PRINCÍPIOS GLOBAIS E ESPECÍFICOS (2011)

A dimensão tática deve ser entendida como centro do processo de ensino-aprendizagem no futebol, assumindo seu caráter organizativo, multidimensional, intencional e consciente. Este artigo teve como foco, apresentar conceitos e conteúdos para sustentação de um processo de ensino aprendizagem, baseado na dimensão tática e na interdependência de três aspectos fundamentais: metodologia para compreensão tática, princípios de jogo e modelos de jogo. Foram sugeridos e descritos em específico, princípios e modelos de jogo direcionados para diferentes faixas etárias, sendo estes compostos por peculiaridades comuns aos jogos esportivos coletivos de invasão.
Nonlinear Model Predictive Control of Position and Attitude in a Hexacopter with Three Failed Rotors (2018)

We applied nonlinear model predictive control (NMPC) to an unmanned aerial vehicle (a hexacopter) with three failed rotors out of the six rotors available. We considered three cases of failure: a case in which three rotors in alternate positions stop, a case in which two adjacent rotors and a separate rotor stop, and a case in which three adjacent rotors stop. Simulation results show that, by applying NMPC, the position and attitude of the hexacopter can be controlled from an initial state that significantly deviates from a state of equilibrium in consideration of constraints. Moreover, we simulated a case in which there was no static equilibrium state and succeeded in controlling the hexacopter's position.
Obscurin and titin as interacting partners during cardiac differentiation and remodeling (2008)

Obscurin is a recently identified giant muscle protein that binds titin, another giant muscle protein of the immunoglobulin superfamily. Both proteins, in addition to their structural domains, contain the kinase‐like domains that appear to be involved in signal transduction. Little is known about the structural relationship and the expression dynamics of these proteins during growth and adaptive reactions of cardiac muscle. The goal of this study was to comparatively investigate the localization patterns of these proteins during differentiation and remodeling of cardiac myocytes in vivo and in cell culture using high resolution confocal microscopy. We also performed the comparative analysis of obscurin and titin incorporation into nascent sarcomeres on the tips of growing myofibrils. We found that obscurin and titin incorporated into forming myofibrils relatively early, before the establishment of registered, aligned pattern of myofibril structure typical of the mature contractile system. Co‐localization of titin and obscurin at the level of the Z‐discs and their close topographical apposition at the A‐I band interfaces of sarcomeres indicate their structural interaction within these structures. The labeling patterns of obscurin and titin expression rapidly changed during structural remodeling of differentiated cardiomyocytes and appear to be one of the earliest detectable markers of this process. Interestingly, downregulation of both obscurin and titin resulted in similar changes in the structure of the contractile system of cardiac myocytes. These data suggest the synergistic involvement of these two proteins in the support of the structural integrity of the contractile apparatus in cardiac muscle. Supported by MDA3803 and NIH HL075093
Real-World Systemic Therapy Treatment Patterns for Squamous Cell Carcinoma of the Head and Neck in Canada (2019)

Our analysis provides real-world insight into scchn clinical practice patterns in Canada, which could inform reimbursement decision-making. High use of platinum-based regimens in first-line drug treatment was generally reflective of treatment guidelines; cetuximab use in the second-line was higher than anticipated. Additional real-world studies are needed to understand the effect of novel therapies such as immuno-oncology agents on clinical practice and outcomes, particularly for recurrent or metastatic scchn.
Crucial role of pyrophosphate in the aminoacylation of E. coli tRNAPhe by yeast phenylalanyl‐tRNA synthetase (1992)

Rapid inactivation of the yeast phenylalanyl-tRNA synthetase in the course of aminoacylation of the heterologous E. coli tRNA(Phe) is observed. This inactivation occurs due to the formation of the tight complex of the enzyme with the pyrophosphate formed during the aminoacylation reaction. This complex is shown to be the normal intermediate of the reaction. Possible inactivation mechanism and correlation between structural differences of yeast and E. coli tRNAs(Phe) with the changes in the enzymatic mechanism of aminoacylation are discussed.
Renal Preservation Despite 35 Days of Partial Bladder Obstruction in the Fetal Lamb (1995)

To determine whether the increase in renal blood flow and preservation of renal function that we demonstrated after 10 days of chronic partial bladder obstruction in the third trimester fetal lamb also occur after earlier longer obstruction, we modified our preparation and studied the effects of 35 days of obstruction begun during the second trimester. Partial bladder obstruction was created in 10 fetal lambs at 90 days of gestation (term equals 147 days). At repeat surgical intervention 28 days later vascular catheters and a left renal artery flow transducer were placed, and catheters were externalized. We then studied renal blood flow and function at gestational ages 120 days and 125 days after 30 days and 35 days of obstruction, respectively. Tissue was obtained for histology at the time of sacrifice. Eight control fetal lambs without obstruction were studied in a similar way. Bilateral hydroureteronephrosis was noted in all fetal lambs after partial obstruction, whereas the kidneys and bladders of the control animals had a normal appearance. Renal blood flow was higher in the obstructed fetal lambs than in controls (20.2 +/- 4.9 versus 10.2 +/- 0.9 ml. per minute per kg., p < 0.05 after 30 days and 17.1 +/- 2.7 versus 9.7 +/- 0.9 per minute per kg., p < 0.05 after 35 days). There was no evidence of decreased renal function by any parameter and, in fact, glomerular filtration rate and urine volume were increased after 30 days of obstruction (1.59 +/- 0.32 versus 0.69 +/- 0.07 ml. per minute per kg., p < 0.05 and 15.7 +/- 4.3 versus 5.2 +/- 0.8 ml. per hour per kg., p < 0.05, respectively). Histological studies demonstrated normal architecture of the kidneys but thinned cortex. We conclude that the physiological responses of the fetus are such that partial lower urinary tract obstruction in our preparation results in a prolonged increase in renal blood flow and preservation of renal function.
A C-based synthesis system, Bach, and its application (invited talk) (2001)

In system LSI design, a desirable system is one that allows the designer to describe, partition, and verify systems, and to generate circuits efficiently. In this paper, we describe a C-based system LSI design system called Bach which we have developed. Using the example of an MEPG-4 video codec design, we summarize its design flow, effects and current issues.
Interaction of some beta-receptor blockers with the transport system of glucose in human erythrocytes. (1985)

The influence of 15 of the most frequently used beta-receptor blockers on the glucose transport in human erythrocytes was investigated. It was found out that 10 compounds have no effect on the glucose transport and that their lipophilicities are very low. The inhibition constants and the inhibition kinetics of the glucose uptake of the other 5 beta-receptor blockers were estimated. No correlation exists between their affinities to the glucose transport sites and the partition coefficients.
Respiratory health and lung research in New Zealand (2006)

This article summarizes the recent history of respiratory research in New Zealand which was triggered by an epidemic of asthma mortality in the 1980s and which led to the rapid emergence of quality research groups. This unique event led to major initiatives to improve the standards of care for people with asthma in New Zealand. Perspectives on other lung health issues including tobacco control, the COPD epidemic and the emergence of bronchiectasis as a serious respiratory disease are also provided.
Nanocomposites Derived from Sulfonated Poly(butylene terephthalate) (2002)

The effect of sodium sulfonate functionalization of poly(butylene terephthalate) (PBT) on the properties of PBT/montmorillonite composites was studied. The results of the study clearly showed that organic modification of montmorillonite clay coupled with the modification of PBT with low levels (1.0−5.0 mol %) of −SO3Na groups results in the production of highly exfoliated nanocomposites by a simple extrusion process. With regard to the effect of −SO3Na content, as little as 1.0 mol % −SO3Na groups was needed to achieve considerable exfoliation of R4N+ montmorillonite. Although the degree of exfoliation was not observed to be strongly dependent on −SO3Na content, mechanical properties such as Young's modulus and high-temperature storage moduli at temperatures above Tg increased with increasing −SO3Na content. These enhancements in mechanical properties produced by a higher −SO3Na content were due to an increase in the number of interactions between the clay particles and the matrix via electrostatic interactions involving the −SO3Na groups.
Partial discharge measurements in air and argon at low pressures with and without a dielectric barrier (2005)

Partial discharge (PD) characteristics in air and argon under low pressures down to 13.3 Pa (0,1 Torr) and 60 Hz AC energization are studied in an energized needle-plane electrode arrangement. The electrode configuration, vacuum chamber, facilities, and electrical connections for the experimental setup are described. Two cases are studied for each of two gases, air and argon, with 20 mm spacing between the two electrodes: (1) with and (2) without a Teflon/spl reg/ cap (dielectric barrier). Results for the four series of experiments and analysis of the discharge current pulse waveforms are presented. Topics discussed are the typical waveforms of the discharge current pulses at different pressures, and discharge current pulse rise time vs. pressure relationships.
Multinuclear Solid-State NMR Characterization, Ion Dissociation, and Dynamic Properties of Lithium-Doped Organic−Inorganic Hybrid Electrolytes Based on Ureasils (2007)

Solid organic−inorganic hybrid electrolytes based on diureasils doped with LiClO4 have been obtained by the sol−gel process through the reaction of poly(propylene glycol)-block-poly(ethylene glycol)-block-poly(propylene glycol) bis(2-aminopropyl ether) (H2N−PPG−PEG−PPG−NH2) with 3-isocyanatepropyltriethoxysilane (ICPTES), followed by co-condensation of an epoxy trialkoxysilane, 3-(glycidyloxypropyl)trimethoxylsilane (GLYMO). The structural and dynamic properties of the materials were systematically investigated by a variety of techniques including ac impedance, Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), multinuclear (13C, 29Si, 7Li) solid-state NMR, 1H−13C 2D WISE (wide-line separation) NMR, and 7Li pulsed gradient spin−echo (PGSE) NMR measurements. The length of backbone PEG chain, the extent of GLYMO cross-linking, and the salt concentration were varied in order to obtain the materials with high conductivities. A maximum ionic conductivity value of 1.37 × 10-5 S/cm was obtained at 30 °C for the hybrid electrolyte with a [O]/[Li] ratio of 32. This ionic conductivity value is 1 order of magnitude higher than that of previously characterized electrolytes based on ureasils without incorporation of GLYMO. The results of 13C cross-polarization magic-angle spinning (CPMAS) NMR with varying contact times and 1H−13C WISE NMR provided a microscopic view of the effects of salt concentrations on the dynamic behavior of the polymer chains. Only one distinct 7Li local environment was detected by variable temperature 7Li−{1H} MAS NMR. The temperature dependence of 7Li static line widths and self-diffusion coefficients showed that there is a strong correlation between the dynamic properties of the charge carriers and the bulk ionic conductivity.
Learning Cross-Lingual IR from an English Retriever (2022)

Yulong Li, Martin Franz, Md Arafat Sultan, Bhavani Iyer, Young-Suk Lee, Avirup Sil. Proceedings of the 2022 Conference of the North American Chapter of the Association for Computational Linguistics: Human Language Technologies. 2022.
Untersuchungen im System Niob-Stickstoff: I. Eigenschaftsänderungen von Niob durch gelösten Stickstoff☆ (1966)

Zusammenfassung Der elektrische Widerstand, der Gitterparameter, die Harte und die Dampfung von Niob-Stickstoff-Mischkristallen wurden in Abhangigkeit von der Stickstoffkonzentration zwischen 0 und 1,5 At % N bestimmt. Die genannten Eigenschaften hangen weitgehend linear vom Stickstoffgehalt ab. Bei der Losung von 1 At % N in vorher entgastem Niob steigt der elektrische Widerstand bei 10° C von 14,1 auf 18,2 μ Ω. cm, der Gitterparameter bei 20° C von 3,3000 auf 3,3041 A und die Mikroharte (50 g Belastung) bei 20° C von 63 auf 245 kg/mm2 an. Das Stickstoff-Dampfungsmaximum bei 270° C (Frequenz 0,73 Hz) erreicht bei 0,5 At % N einen Wert von β = 560 × 10 −4 . Die Aktivierungsenergie des einfachen Relaxationsvorganges betragt 33,8 kcal/mol. Die Eigenschaftsanderungen von Niob durch gelosten Stickstoff wurden mit den entsprechenden Werten fur die Mischkristallreihen Niob-Sauerstoff, Tantal-Stickstoff, Tantal-Sauerstoff, Vanadium-Stickstoff und Vanadium-Sauerstoff verglichen.
Immersive Integration for Virtual and Human-Centered Environments (2005)

Summary form only given. We envision future work and play environments that are more effectively human-centered with the user's computing interface being more closely integrated with the physical surroundings than today's conventional computer display screens and keyboards. We are working toward realizable versions of such environments, in which multiple video projectors and digital cameras enable every visible surface to be both measured in 3D and used for display. If the 3D surface positions are transmitted to a distant location, they may also enable distant collaborations to become more like working in adjacent offices connected by large windows. In one prototype, depth maps are calculated from streams of video images and the resulting 3D surface points are displayed to the user in head-tracked stereo. Another prototype allows direct "painting" onto movable objects - a dollhouse, for example. One long-term goal is advanced training for trauma surgeons by immersive replay of recorded procedures. More generally, we hope to demonstrate that the principal interface of a future computing environment need not be limited to a screen the size of one or two sheets of paper. Just as a useful physical environment is all around us, so too can the increasingly ubiquitous computing environment be all around us - becoming more effectively human-centered and integrated into our physical surroundings.
Incidence of adverse drug reactions in geriatric wards of university hospitals (2004)

Adverse drug reactions (ADR) in elderly people, which have been shown to increase with age, are often attributed to functional decline and polypharmacy. A multi-institutional retrospective survey was undertaken to investigate the current status of ADR in geriatric wards of university hospitals. The inpatient database from 2000 to 2002 in 5 university hospitals was studied, and a total of 1,289 patients were analyzed. The incidence of ADR, as determined by attending physicians, was 9.2% on the whole but varied from 6.3% to 15.8% among the institutions. The factors significantly related to ADR were number of diagnoses, number of geriatric syndromes, number of prescribed drugs, increase of more than two drugs during admission, longer hospital stay, emergency admission, depression and apathy. These results are mostly consistent with previous reports and will provide important information on pharmacotherapy in elderly people.