gebhart/patrepeval huggingface dataset:
Comment on Effect of Polar Solvents on the Optical Properties of Water-Dispersible Thiol-Capped Cobalt Nanoparticles (2008)

ADVERTISEMENT RETURN TO ISSUEPREVCommentComment on Effect of Polar Solvents on the Optical Properties of Water-Dispersible Thiol-Capped Cobalt NanoparticlesVladimir Kitaev†View Author Information Chemistry Department, Wilfrid Laurier University, 75 University Avenue West, Waterloo, Ontario, Canada N2L 3C5†E-mail: [email protected].Cite this: Langmuir 2008, 24, 14, 7623–7624Publication Date (Web):June 18, 2008Publication History Received28 February 2008Published online18 June 2008Published inissue 1 July 2008https://pubs.acs.org/doi/10.1021/la800641shttps://doi.org/10.1021/la800641sarticle-commentaryACS PublicationsCopyright © 2008 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views721Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (284 KB) Get e-AlertscloseSUBJECTS:Anions,Cobalt,Metal nanoparticles,Nanoparticles,Thiolates Get e-Alerts
How to become a good surgeon (2023)

Good surgeons are essential for patients. The personal prerequisites, the best way to learn and to teach, and the structural requirements and evaluation criteria for the formation of surgeons are described. A definition of a master surgeon is presented. Even if surgical techniques change in the future, the fundamental relationship between surgeon and patient will remain unchanged.
Collagen cross-linking. Synthesis of collagen cross-links in vitro with highly purified lysyl oxidase. (1976)

<P>Abstract copyright UK Data Service and data collection copyright owner.</P>
Relationships Among Reading Skills of Adults With Low Literacy (2010)

In this study, confirmatory factor analyses were used to examine the interrelationships among latent factors of the simple view model of reading comprehension (word recognition and language comprehension) and hypothesized additional factors (vocabulary and reading fluency) in a sample of 476 adult learners with low literacy levels. The results provided evidence for reliable distinctions between word recognition, fluency, language comprehension, and vocabulary skills as components of reading. Even so, the data did not support the hypothesis that the simple view needs to be expanded to include vocabulary or fluency factors, as has been posited in a few prior studies of younger and more able readers. Rather, word recognition and language comprehension alone were found to account adequately for variation in reading comprehension in adults with low literacy.
GANGRENE OF THE SMALL BOWEL: A COMPLICATION OF METHYSERGIDE THERAPY (1982)

A 49 year old woman with mesenteric vascular fibrosis resulting in infarction of the small bowel after taking methysergide for migraine prophylaxis is presented. Only one other report of this complication of methysergide therapy has been found in the literature although two patients with mesenteric angina have been documented. It appears that timely withdrawal of the drug results in the reversal of the fibrotic process.
Control of matrix stiffness promotes endodermal lineage specification by regulating SMAD2/3 via lncRNA LINC00458 (2020)

During endoderm formation, cell identity and tissue morphogenesis are tightly controlled by cell-intrinsic and cell-extrinsic factors such as biochemical and physical inputs. While the effects of biochemical factors are well studied, the physical cues that regulate cell division and differentiation are poorly understood. RNA sequencing analysis demonstrated increases of endoderm-specific gene expression in hPSCs cultured on soft substrate (Young's modulus, 3 ± 0.45 kPa) in comparison with hard substrate (Young's modulus, 165 ± 6.39 kPa). Further analyses revealed that multiple long noncoding RNAs (lncRNAs) were up-regulated on soft substrate; among them, <i>LINC00458</i> was identified as a stiffness-dependent lncRNA specifically required for hPSC differentiation toward an early endodermal lineage. Gain- and loss-of-function experiments confirmed that <i>LINC00458</i> is functionally required for hPSC endodermal lineage specification induced by soft substrates. Our study provides evidence that mechanical cues regulate the expression of <i>LINC00458</i> and induce differentiation of hPSC into hepatic lineage progenitors.
Light-activated helical inversion in cholesteric liquid crystal microdroplets (2018)

Cholesteric liquid crystal (CLC) droplets exhibit nontrivial topological features, which are controlled by the ratio between the cholesteric pitch and the droplet radius. The radial spherical structure (RSS) is of particular interest, as it reveals an onion-like concentric organization of the cholesteric helices, leading to the expression of spherical Bragg microcavities. Using an overcrowded alkene-based unidirectional molecular motor as a dopant, we show that the topological defect structure in the droplet can be activated by illumination. By using appropriate molecular motor concentrations, light can either break the symmetry of topological defects (as observed for the bent-twisted bipolar structure), or it can induce inversion of handedness in an onion-like organization (in the case of RSS). This latter feature may pave the way toward alternative activation modes of lasers based on cholesteric droplets. By also studying CLC droplets once they have reached full photoconversion at photostationary state (PSS), we highlight that the strong influence of confinement on the droplets structure occurs to the same extent after the helix inversion event. Our results are interpreted in terms of numerical simulations of the droplets' structure, which shed light on the major role played by curvature close to the droplets' center, this latter one becoming dominant when the droplet radius is small.
Development of Visible-Light Driven Cu(I) Complex Photosensitizers for Photocatalytic CO2 Reduction (2019)

The visible-light responsive Cu(I)-complex photosensitizers were developed by introducing various aromatic substituents at the 4,7-positions of a 2,9-dimethyl-1,10-phenanthroline (dmp) ligand in a heteroleptic Cu<sup>I</sup>(dmp)(DPEphos)<sup>+</sup>-type complexes (DPEphos = [2-(diphenylphosphino)phenyl]ether) for photocatalytic CO<sub>2</sub> reduction. Introducing biphenyl groups (Bp-) on the dmp ligand enhanced the molar extinction coefficient (ε) of the metal-to-ligand charge transfer (MLCT) band in the visible region (ε = 7,500 M<sup>-1</sup>cm<sup>-1</sup>) compared to that of the phenyl (Ph-)-containing analog (ε = 5,700 M<sup>-1</sup>cm<sup>-1</sup> at λ<sub>max</sub> = 388 nm). However, introducing 4-R-Ph- groups (R = the electron-withdrawing groups NC-, or NO<sub>2</sub>-) led to a red shift in the band to λ<sub>max</sub> = 390, 400, and 401 nm, respectively. Single-crystal X-ray analysis showed the Ph- groups were twisted because of the steric repulsion between the 2,6-protons of the Ph- groups and 5,6-protons of the dmp ligand. The result strongly indicated that the π-conjugation effect of the 4-R-Ph- groups is so weak that the lowering of the energy of the dmp π<sup>*</sup> orbitals is small. However, when 4-R-ph- was substituted by a 5-membered heterorings, there was a larger red shift, leading to an increase in the ε value of the MLCT absorption band. Thus, the substitution to 2-benzofuranyl- groups resulted in visible-light absorption up to 500 nm and a shoulder peak at around 420 nm (ε = 12,300 M<sup>-1</sup>cm<sup>-1</sup>) due to the expansion of π-conjugation over the substituted dmp ligand. The photocatalytic reaction for CO<sub>2</sub> reduction was tested using the obtained Cu<sup>I</sup> complexes as photosensitizers in the presence of a Fe(dmp)<sub>2</sub>(NCS)<sub>2</sub> catalyst and 1,3-dimethyl-2-phenyl-2,3-dihydro-1<i>H</i>-benzo[d]imidazole as a sacrificial reductant, which showed improved CO generation.
Driver Behavior and Performance with Augmented Reality Pedestrian Collision Warning: An Outdoor User Study (2018)

This article investigates the effects of visual warning presentation methods on human performance in augmented reality (AR) driving. An experimental user study was conducted in a parking lot where participants drove a test vehicle while braking for any cross traffic with assistance from AR visual warnings presented on a monoscopic and volumetric head-up display (HUD). Results showed that monoscopic displays can be as effective as volumetric displays for human performance in AR braking tasks. The experiment also demonstrated the benefits of conformal graphics, which are tightly integrated into the real world, such as their ability to guide drivers' attention and their positive consequences on driver behavior and performance. These findings suggest that conformal graphics presented via monoscopic HUDs can enhance driver performance by leveraging the effectiveness of monocular depth cues. The proposed approaches and methods can be used and further developed by future researchers and practitioners to better understand driver performance in AR as well as inform usability evaluation of future automotive AR applications.
Perlecan is required for the chondrogenic differentiation of synovial mesenchymal cells through regulation of Sox9 gene expression (2016)

We previously reported that perlecan, a heparan-sulfate proteoglycan (Hspg2), expressed in the synovium at the cartilage-synovial junction, is required for osteophyte formation in knee osteoarthritis. To examine the mechanism underlying this process, we examined the role of perlecan in the proliferation and differentiation of synovial mesenchymal cells (SMCs), using a recently established mouse synovial cell culture method. Primary SMCs isolated from Hspg2<sup>-/-</sup> -Tg (Hspg2<sup>-/-</sup> ;Col2a1-Hspg2<sup>Tg/-</sup> ) mice, in which the perlecan-knockout was rescued from perinatal lethality, lack perlecan. The chondrogenic-, osteogenic-, and adipogenic-potentials were examined in the Hspg2<sup>-/-</sup> -Tg SMCs compared to the control SMCs prepared from wild-type Hspg2<sup>+/+</sup> -Tg (Hspg2<sup>+/+</sup> ;Col2a1-Hspg2<sup>Tg/-</sup> ) littermates. In a culture condition permitting proliferation, both control and Hspg2<sup>-/-</sup> -Tg SMCs showed similar rates of proliferation and expression of cell surface markers. However, in micromass cultures, the cartilage matrix production and Sox9 and Col2a1 mRNA levels were significantly reduced in Hspg2<sup>-/-</sup> -Tg SMCs, compared with control SMCs. The reduced level of Sox9 mRNA was restored by the supplementation with exogenous perlecan protein. There was no difference in osteogenic differentiation between the control and Hspg2<sup>-/-</sup> -Tg SMCs, as measured by the levels of Runx2 and Col1a1 mRNA. The adipogenic induction and PPARγ mRNA levels were significantly reduced in Hspg2<sup>-/-</sup> -Tg SMCs compared to control SMCs. The reduction of PPARγ mRNA levels in Hspg2<sup>-/-</sup> -Tg SMCs was restored by supplementation of perlecan. Perlecan is required for the chondrogenic and adipogenic differentiation from SMCs via its regulation of the Sox9 and PPARγ gene expression, but not for osteogenic differentiation via Runx2. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:837-846, 2017.
Investigating SARS-CoV-2 infection and the health and psychosocial impact of the COVID-19 pandemic in the Canadian CHILD Cohort: study methodology and cohort profile (2022)

Abstract Background The COVID-19 pandemic is affecting all Canadian families, with some impacted differently than others. Our study aims to: 1) determine the prevalence and transmission of SARS-CoV-2 infection among Canadian families, 2) identify predictors of infection susceptibility and severity of SARS-CoV-2 and 3) identify health and psychosocial impacts of the COVID-19 pandemic. Methods This study builds upon the CHILD Cohort Study, an ongoing multi-ethnic general population prospective cohort consisting of 3454 Canadian families with children born in Vancouver, Edmonton, Manitoba, and Toronto between 2009-12. During the pandemic, 1462 CHILD households (5378 individuals) consented to participate in the CHILD COVID-19 Add-On Study involving: (1) brief biweekly surveys about COVID-19 symptoms and testing; (2) quarterly questionnaires assessing COVID-19 exposure, testing and vaccination status, physical and mental health, and pandemic-driven life changes; (3) in-home biological sampling kits to collect blood and stool. Mean ages were 9 years (range 0-17) for children and 43 years (range 18-85) for adults. Prevalence of SARS-CoV-2 infection will be estimated from survey data and confirmed through serology testing. We will combine these new data with a wealth of pre-pandemic CHILD data and use multivariate modelling and machine learning methods to identify risk and resilience factors for susceptibility and severity to the direct and indirect effects of the pandemic. Interpretation Our short-term findings will inform key stakeholders and knowledge users to shape current and future pandemic responses. Additionally, this study provides a unique resource to study the long-term impacts of the pandemic as the CHILD Cohort Study continues.
Novel Aspects of the Biochemistry of the Molybdenum Cofactor (1991)

This chapter contains sections titled: Introduction The Evidence The Strategy for Structural Characterization Structural Studies on Mo Cofactor Derivatives A Proposed Structure for Molybdopterin The Entrapment Structure of Alkylated Molybdopterin Probing the Functional Features of Molybdopterin A Dinucleotide Analog of Molybdopterin Why a Pterin? Probing the Oxidation State of Molybdopterin Biosynthesis of Molybdopterin Molybdopterin Biosynthesis IN Humans Perspectives
Robust MPC with data-driven demand forecasting for frequency regulation with heat pumps (2022)

With the increased amount of volatile renewable energy sources connected to the electricity grid, and the phase-out of fossil fuel based power plants, there is an increased need for frequency regulation. On the demand side, frequency regulation services can be offered by buildings or districts that are equipped with electric heating or cooling systems, by exploiting their thermal inertia. Existing approaches for tapping into this potential typically rely on dynamic building models, which in practice can be challenging to obtain and maintain. As a result, practical implementations of such systems are scarce. Moreover, actively controlling buildings requires extensive control infrastructure and may cause privacy concerns in district energy systems. Motivated by this, we exploit the thermal inertia of buffer storage for reserves, reducing the building models to demand forecasts here. By combining a control scheme based on Robust Model Predictive Control, with affine policies, and heating demand forecasting based on Artificial Neural Networks with online correction methods, we offer frequency regulation reserves and maintain user comfort with a system comprising a heat pump and buffer storage. While the robust approach ensures occupant comfort, the use of affine policies reduces the effect of disturbance uncertainty on the system state. In a first-of-its-kind experiment with a real district-like building energy system, we demonstrate that the scheme is able to offer reserves in a variety of conditions and track a regulation signal while meeting the heating demand of the connected buildings. 13.4% of the consumed electricity is flexible. In additional numerical studies, we demonstrate that using affine policies significantly decreases the cost function and increases the amount of offered reserves and we investigate the suboptimality in comparison to an omniscient control system.
Performance of strained InGaAs/InAlAs multiple-quantum-well electroabsorption modulators (1996)

The performance of a strained InGaAs/InAlAs multiple-quantum-well (MQW) electroabsorption (EA) modulator was evaluated theoretically and experimentally, The theoretical analysis showed that adding tensile strain to the InGaAs wells widens the wells and reduces the driving voltage; it also showed that adding compressive strain to the InAlAs barriers reduces the band discontinuities and increases the optical saturation power. A fabricated InGaAs/InAlAs MQW modulator with tensile strain in the wells and compressive strain in the barriers had a large modulation bandwidth (f/sub 3 dB/>20 GHz) and a lower driving voltage (V/sub 15 dB/=1.2 V) compared to an unstrained InGaAs/InAlAs MQW modulator, so it had a higher modulation efficiency (17 GHz/V). This strained MQW modulator produced a 10 Gb/s optical signal with a clear eye opening and small chirping (/spl alpha//sub eff/=0.6). Moreover, it had shorter carrier escape times, so it has better optical saturation behavior. Introducing strain thus significantly improves the performance of the MQW-EA modulators.
Quasi 2D Mesoporous Carbon Microbelts Derived from Fullerene Crystals as an Electrode Material for Electrochemical Supercapacitors (2017)

Fullerene C<sub>60</sub> microbelts were fabricated using the liquid-liquid interfacial precipitation method and converted into quasi 2D mesoporous carbon microbelts by heat treatment at elevated temperatures of 900 and 2000 °C. The carbon microbelts obtained by heat treatment of fullerene C<sub>60</sub> microbelts at 900 °C showed excellent electrochemical supercapacitive performance, exhibiting high specific capacitances ca. 360 F g<sup>-1</sup> (at 5 mV s<sup>-1</sup>) and 290 F g<sup>-1</sup> (at 1 A g<sup>-1</sup>) because of the enhanced surface area and the robust mesoporous framework structure. Additionally, the heat-treated carbon microbelt showed good rate performance, retaining 49% of capacitance at a high scan rate of 10 A g<sup>-1</sup>. The carbon belts exhibit super cyclic stability. Capacity loss was not observed even after 10 000 charge/discharge cycles. These results demonstrate that the quasi 2D mesoporous carbon microbelts derived from a π-electron-rich carbon source, fullerene C<sub>60</sub> crystals, could be used as a new candidate material for electrochemical supercapacitor applications.
Patient‐reported outcomes with subcutaneous immunoglobulin in chronic inflammatory demyelinating polyneuropathy: the PATH study (2019)

IgPro20 maintained or improved QOL in most subjects with CIDP, consistent with the PATH study findings that both IgPro20 doses were efficacious in maintaining CIDP.
The Cytokine and Chemokine Profiles in Patients with Hand, Foot and Mouth Disease of Different Severities in Shanghai, China, 2010 (2013)

Whether steroid treatment has any beneficial effect on the prognosis of HFMD patients requires to be further investigated.
Dictionary Representations for Electrode Displacement Elastography (2018)

Ultrasound electrode displacement elastography (EDE) has demonstrated the potential to monitor ablated regions in human patients after minimally invasive microwave ablation procedures. Displacement estimation for EDE is commonly plagued by decorrelation noise artifacts degrading displacement estimates. In this paper, we propose a global dictionary learning approach applied to denoising displacement estimates with an adaptively learned dictionary from EDE phantom displacement maps. The resulting algorithm is one that represents displacement patches sparsely if they contain low noise and averages remaining patches thereby denoising displacement maps while retaining important edge information. The results of dictionary-represented displacements presented with a higher signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR) with improved contrast, as well as improved phantom inclusion delineation when compared to initial displacements, median-filtered displacements, and spline smoothened displacements, respectively. In addition to visualized noise reduction, dictionary-represented displacements presented with the highest SNR, CNR, and improved contrast with values of 1.77, 4.56, and 4.35 dB, respectively, when compared to axial strain tensor images estimated using the initial displacements. Following EDE phantom imaging, we utilized dictionary representations from in vivo patient data, further validating efficacy. Denoising displacement estimates are a newer application for dictionary learning producing strong ablated region delineation with little degradation from denoising.
Design on MBE material structure of GaAs-based RTD (2002)

The Resonant tunneling diode (RTD) is a high speed nanoelectronic device based on quantum resonant tunneling effect. It has the advantage of high frequency, low operating Voltage, low power dissipation, negative resistance, bistability and self-latching. It can be applied in high speed integrated circuits widely. Based on the analysis of correlation between the device characteristic parameters and the material structure parameters, some design rules have been summarized as following: 1. The barrier width L<sub>B</sub> of RTD should be selected as narrow as possible to increase the peak current density J<sub>p</sub>. 2. The well width L<sub>W</sub> should be selected slightly wider to decrease the peak Voltage V<sub>p</sub>. 3. The spacer width L<sub>S</sub> should be selected slightly narrower to decrease the peak Voltage V<sub>p</sub>. 4. The emitter doping density N<sub>E</sub> should be determined to a reasonable value to avoid both R<sub>S</sub> and intrinsic capacitance C<sub>d</sub> too much. 5. Selecting AlAs as the barrier material to increase the barrier height then to increase peak valley current ratio (PVCR). 6. In emitter region, adding a narrow bandgap material layer to form a subwell. The 3dimension/2dimension resonant tunneling changes to 2dimension/3dimension resonant tunneling, the PVCR will be improved. From above design rules, The GaAs based MBE material structure of RTD has been designed, The RTD devices have been fabricated from this material structure shown very good performance. Main characteristic parameters listed as following: Room temperature PVCR 7.6, f<sub>R</sub>=54GHZ, switching time t<sub>r</sub>&#8776;171ps.