gebhart/patrepeval huggingface dataset:
Hydrogen‐Bonding Pincer Complexes with Two Protic N‐Heterocyclic Carbenes from Direct Metalation of a 1,8‐Bis(imidazol‐1‐yl)carbazole by Platinum, Palladium, and Nickel (2015)

Pincer protic N-heterocyclic carbene (PNHC) complexes were synthesized by direct metalation, the formation of a metal carbon bond from an unfunctionalized CH bond in a single synthetic step. Significantly, direct metalation succeeded even for a first-row metal, nickel. The chloride complexes were isolated and then converted to the acetate, triflate, or in the platinum case, a hydride analogue. Crystal structures and (1) H, (13) C, and (15) N NMR data, as well as IR spectra, document the effects of intramolecular hydrogen bonding and the planar but flexible pincer framework. Anti-Markovnikov addition of OH bonds to alkynes, including catalyzed alkyne hydration, were demonstrated on the Pt triflate analog.
NAIL: an evolutionarily conserved lncRNA essential for licensing coordinated activation of p38 and NFκB in colitis (2020)

<i>NAIL</i> directly regulates initiation and progression of colitis and its expression is highly correlated with NFκB activity which makes it a perfect candidate to serve as a biomarker and a therapeutic target for IBD and other inflammation-associated diseases.
Interleukin-17 and Interferon-γ Are Produced Concomitantly by Human Coronary Artery–Infiltrating T Cells and Act Synergistically on Vascular Smooth Muscle Cells (2009)

Our findings demonstrate that IL-17 is produced concomitantly with IFN-gamma by coronary artery-infiltrating T cells and that these cytokines act synergistically to induce proinflammatory responses in vascular smooth muscle cells.
Determining Essential Statistics for Cost Based Optimization of an ETL Workflow (2014)

Many of the ETL products in the market today provide tools for design of ETL workflows, with very little or no support for opti-mization of such workflows. Optimization of ETL workflows pose several new challenges compared to traditional query optimization in database systems. There have been many attempts both in the industry and the research community to support cost-based opti-mization techniques for ETL Workflows, but with limited success. Non-availability of source statistics in ETL is one of the major chal-lenges that precludes the use of a cost based optimization strategy. However, the basic philosophy of ETL workflows of design once and execute repeatedly allows interesting possibilities for determin-ing the statistics of the input. In this paper, we propose a frame-work to determine various sets of statistics to collect for a given workflow, using which the optimizer can estimate the cost of any alternative plan for the workflow. The initial few runs of the work-flow are used to collect the statistics and future runs are optimized based on the learned statistics. Since there can be several alterna-tive sets of statistics that are sufficient, we propose an optimization framework to choose a set of statistics that can be measured with the least overhead. We experimentally demonstrate the effective-ness and efficiency of the proposed algorithms.
Refined Structure of Charybdotoxin: Common Motifs in Scorpion Toxins and Insect Defensins (1991)

Conflicting three-dimensional structures of charybdotoxin (Chtx), a blocker of K+ channels, have been previously reported. A high-resolution model depicting the tertiary structure of Chtx has been obtained by DIANA and X-PLOR calculations from new proton nuclear magnetic resonance (NMR) data. The protein possesses a small triple-stranded antiparallel beta sheet linked to a short helix by two disulfides and to an extended fragment by one disulfide, respectively. This motif also exists in all known structures of scorpion toxins, irrespective of their size, sequence, and function. Strikingly, antibacterial insect defensins also adopt this folding pattern.
ChemInform Abstract: Highly Efficient Rhodium‐Catalyzed Transfer Hydrogenation of Nitroarenes into Amines and Formanilides. (2014)

Abstract The reduction of nitroarenes to formanilides succeeds with catalyst loadings as low as 0.1 mol% at 100°, but may require 2 mol% of catalyst for ortho‐substituted or strongly coordinating substrates.
Intraoperative Photodynamic Evaluation of Surgical Margins During Endoscopic Extraperitoneal Radical Prostatectomy with the Use of 5-Aminolevulinic Acid (2009)

Laparoscopy offers an appropriate setting for the use of PDD in prostate cancer to visualize possible PSM. Although imaging of PSM by PDD is promising with the technique being feasible and safe, larger series are needed to prove the reproducibility of our results.
ChemInform Abstract: Synthesis of Stereoisomerically Pure Monoether Lipids. (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
InAs/GaSb Heterostructure Nanowires for Tunnel Field-Effect Transistors (2010)

InAs/GaSb nanowire heterostructures with thin GaInAs inserts were grown by MOVPE and characterized by electrical measurements and transmission electron microscopy. Down-scaling of the insert thickness was limited because of an observed sensitivity of GaSb nanowire growth to the presence of In. By employing growth interrupts in between the InAs and GaInAs growth steps it was possible to reach an insert thickness down to 25 nm. Two-terminal devices show a diode behavior, where temperature-dependent measurements indicate a heterostructure barrier height of 0.5 eV, which is identified as the valence band offset between the InAs and GaSb. Three-terminal transistor structures with a top-gate positioned at the heterointerface show clear indications of band-to-band tunnelling.
Balancing glycolytic flux: the role of 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatases in cancer metabolism (2013)

The increased glucose metabolism in cancer cells is required to fulfill their high energetic and biosynthetic demands. Changes in the metabolic activity of cancer cells are caused by the activation of oncogenes or loss of tumor suppressors. They can also be part of the metabolic adaptations to the conditions imposed by the tumor microenvironment, such as the hypoxia response. Among the metabolic enzymes that are modulated by these factors are the 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatases (PFKFBs), a family of bifunctional enzymes that control the levels of fructose 2,6-bisphosphate (Fru-2,6-P2). This metabolite is important for the dynamic regulation of glycolytic flux by allosterically activating the rate-limiting enzyme of glycolysis phosphofructokinase-1 (PFK-1). Therapeutic strategies designed to alter the levels of this metabolite are likely to interfere with the metabolic balance of cancer cells, and could lead to a reduction in cancer cell proliferation, invasiveness and survival. This article will review our current understanding of the role of PFKFB proteins in the control of cancer metabolism and discuss the emerging interest in these enzymes as potential targets for the development of antineoplastic agents.
Reticulocyte changes after experimental anemia and erythropoietin treatment of horses (2005)

Availability of recombinant human erythropoietin (EPO) has facilitated use to enhance red blood cell production, and therefore aerobic performance, in human and equine athletes. Recombinant human EPO promotes growth and differentiation of equine erythroid precursor cells, but in some horses repeat administration induces immune interference with endogenous EPO resulting in fatal anemia. Although blood reticulocyte parameters acquire unique changes in humans treated with EPO, with manual enumeration methods, horses were not considered to release reticulocytes from the bone marrow into circulation, even under severe erythropoietic stress. The goals of this study were to determine whether reticulocytes could be detected and characterized in horses that are anemic or have been treated with EPO using a modern hematology analyzer. Anemia was induced in six horses by removal of 30 ml of blood/kg of body wt over 24 h. After 28 days, the horses were treated twice with 55 U/kg of EPO (Eprex), and after 65 days they were treated thrice with 73 U/kg of EPO. Blood samples were analyzed with the ADVIA120 instrument every 3-5 days and bone marrow samples 7 days after anemia and EPO treatments. Analysis of blood reticulocyte parameters by ANOVA in a randomized complete block design determined that anemia and EPO induced significant (P < or = 0.05) increases in red cell distribution width and reticulocyte mean cell volume. Parameters changed only after EPO treatment were cellular hemoglobin concentration mean, mean cell volume, reticulocyte concentration, proportion of macrocytic reticulocytes, and reticulocyte cellular hemoglobin. These findings indicate that horses under erythropoietic stress and after EPO treatment release reticulocytes with unique characteristics into circulation.
Parallel Dynamics Computation and H∞ Acceleration Control of Parallel Manipulators for Acceleration Display (2004)

In this paper, we propose a control scheme of parallel manipulators focusing on the accuracy of acceleration on the end plate, an important factor when parallel manipulators are used as acceleration displays such as a driving simulator. In order to achieve a smooth and accurate acceleration on the end plate, we combine two controllers: A dynamic controller to achieve accuracy of the position and to stabilize the system, and an H∞ controller to feedback the acceleration of the end plate to cope with the unmodeled dynamics such as mechanical flexibility and friction. The main problem of dynamic control is computational complexity. We applied parallel processing to reduce the latency and realized real-time dynamic control. The designed H∞ controller is added outside the closed loop of dynamic control to remove the vibration of the structure and the influence of unmodeled dynamics.
Compact LHM-based band-stop filter (2010)

In this paper, a compact, low-insertion-loss, high selective band-stop filter is proposed. The filter is composed of four unit cells, two of which are anti-symmetrically connected left-handed metamaterial (LHM) unit cells in combination with their mirror images to obtain the symmetric return losses at both ports. The design of LHM unit cell is based on direct connection of spiral resonator and thin wire to decrease the band-stop frequency further than the conventional split ring resonator designs. The dimensions of the proposed structure are as small as 9.7 mm × 20 mm, while high frequency selectivity could be achieved due to the transmission zeros. The filter has an insertion loss of better than 2 dB even with highly lossy FR4 substrate, and a return loss of larger than 10 dB in the passbands of 2.41-2.65 GHz and 4.26-5.72 GHz. The band rejection of greater than 30 dB is numerically calculated within 3.16-3.54 GHz with high frequency selectivity of 69 dB/GHz.
Safety and nutritional value of a dried killed bacterial biomass from Escherichia coli (FERM BP‐10941) (PL73 (LM)) as a feed material for pigs, ruminants and salmonids (2017)

PL73 (LM) is a dried, heat-inactivated bacterial biomass used as a feed material produced from an <i>Escherichia</i> <i>coli</i> K-12 strain, which was genetically modified to overproduce lysine. The recipient organism <i>E. coli</i> K-12S B-7 is considered to be safe. The traits introduced in the final modified strain <i>E. coli</i> FERM BP-10941 are mainly limited to the overproduction of lysine. No full-length antibiotic resistance genes or other sequences of concern remain in the modified strain. In conclusion, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) does not identify risks for human and animal health or the environment from the biomass regarding the genetic modification of the strain. Although considering the zootechnical end-points only, the maximum safe level for dairy cows would be 6% PL73 (LM) of feed dry matter (~ 5% in complete feed) and for pigs for fattening up to 6% PL73 (LM), the unexplained effects on blood coagulation, on plasma lipoproteins in dairy cows and on total plasma bilirubin and liver weight in pigs prevent a clear conclusion of safe dietary levels for ruminants and pigs for fattening. PL73 (LM) is safe for salmonids up to a dietary concentration of 13%. The toxicological data indicate adverse effects of PL73 (LM) on blood coagulation and liver, which also occur in target species. As a consequence, the FEEDAP Panel is unable to conclude on the safety for the consumer of products derived from animals receiving feed containing PL73 (LM). PL73 (LM) is not considered a skin/eye irritant but should be considered as a potential skin and respiratory sensitiser. Moreover, any exposure of users to dust from the product via the inhalation route should be considered a serious risk. The FEEDAP Panel considers that substitution of PL73 (LM) for other protein-rich feed materials will not adversely affect the environment.
Friction Reducing Effect of and Design Guidelines for Groove Shaped Surface Texturing under Reciprocating Lubrication (2022)

The present paper refers to our study on reducing friction on reciprocating sliding surfaces by surface texturing. The purpose of this study is to develop optimal design guidelines for surface texturing by clarifying its effect on the lubrication characteristics of reciprocating sliding surfaces under various operating conditions. Numerical analysis has been performed by solving the Reynolds equation using the finite element method to evaluate the effect of surface texturing．The major results are that; 1) The reciprocating friction characteristics of a barrel face slider with groove-shaped surface texturing can be organized by the bearing modulus consisting of the viscosity coefficient of the lubricant, average sliding speed, and surface pressure.; 2) Friction loss is reduced by applying groove-shaped surface texturing with appropriate depth and arrangement according to the value of bearing modulus, as compared with the case of no texturing.
Semiconductor laser nonlinear dynamics: Complexity made useful (2009)

I summarize here some of our recent contributions to the understanding and applications of semiconductor nonlinear dynamics. Interplay between polarization switching properties of VCSELs and external optical injection/optical feedback/current modulation gives rise to a rich variety of new dynamical phenomena characterized by multimode behavior, bistability, self-pulsing, noise-induced or noise-sustained instabilities. In these configurations control of polarization is possible but also new perspectives can be expected where the dynamical complexity would help for all-optical signal processing. I will conclude with recent theoretical and experimental works on polarization and nonlinear dynamical properties of quantum dot semiconductor lasers.
Pulsed injection control of a titanium-doped sapphire laser (1986)

Injection control of a tunable Ti:sapphire laser using a narrow-bandwidth pulsed dye laser operating at a wavelength removed from the peak of the Ti:sapphire-laser gain curve is reported. The free-running Ti:sapphire laser had broadband laser emission from 750 to 790 nm. Injection at 727 nm resulted in essentially complete energy extraction at that wavelength in a 2.5-pm bandwidth matching the injection source.
Intelligent Diagnostic Requirements of Future All-Electric Ship Integrated Power System (2007)

Future ship integrated power systems (IPSs) will be characterized by complex topologies of advanced power electronics and other evolving components. Advanced capabilities, such as intelligent reconfiguration of system function and connectivity will be possible; however, system level knowledge of component failure will be needed for intelligent power distribution under failure mode conditions. Diagnostic and prognostic coverage for sensors, components, and subsystems will be essential for achieving reliability goals. This paper will look at some diagnostic requirements and emerging technologies available for insertion into future ship IPSs
The Nature of Sleepiness: Causes, Contexts, and Consequences (2020)

The effect of lapses on performance varies with the nature of the task, however, such that subject-paced tasks show response slowing when lapses occur, while experimenter-paced tasks show increased errors when lapses occur. Despite the lack of demonstrated pathophysiology associated with human sleepiness, operationalizing sleepiness has become an increasingly important issue in the fields of sleep and human chronobiology. At any given time, sleepiness is the composite result of different temporal patterns for the effects of prior wakefulness, sleep disturbance, the preceding state, and the circadian phase. Boredom, heat, a large meal, and an uninteresting task are the most common contexts in which attributions of sleepiness are made, but they do not always result in sleepiness. The occurrence of voluntary sleep onsets and increased sleep tendency in the middle of the night and the middle of the day should, if they are indicative of increased daytime sleepiness, be accompanied by involuntary sleep onsets at these same times.
[The study of ovarian autoimmunity and ovarian reserve in women with uncertain sterility]. (2008)

Antiovarian antibodies were observed only in women who have had laparoscopic ovarian drilling. The frequency of antiovarian antibodies among the Bulgarian women with unknown sterility is 17.05%. The presence of antiovarian antibodies is not associated with poor ovarian reserve as we investigated the levels of FSH, LH, inhibin B on the third day of the menstrual cycle.
EEG-P300 EXTRACTION USING NEURAL NETWORK BASED ADAPTIVE RECURSIVE FILTER AND ADAPTIVE AUTOREGRESSIVE MODELS (2010)

ACTA Press publishes numerous proceedings like technical publications, scientific publications for power and energy systems and research papers for international conferences in the general areas of engineering and computer science.
Gender differences in the relationship between workplace friendships and organisational outcomes (2007)

The current study investigated gender differences in (a) perceived benefits of workplace friendships and (b) the relationship between friendship factors and organisational outcomes. Four hundred and forty-five respondents completed a questionnaire which asked them to describe the benefits they received from workplace friends, and which measured workplace friendship prevalence and opportunities, workgroup cohesion, job satisfaction, organisational commitment and intention to leave. Friendships at work were found to be significantly more strongly correlated with job satisfaction for men. In addition, women were significantly more likely than men to describe the benefits of workplace friendship in terms of social and emotional support, while men were more likely to focus on the benefits friends provided them in their career or in functional aspects of “getting the job done”. Findings are discussed in the context of other organisational and gender research.
Paris Altimetry Precision Prediction with Galileo Signals-in-Space (2008)

This paper presents a complete analysis of the height precision of a GNSS-R space-based altimeter exploiting the forthcoming signals of the European Galileo satellite navigation system. The major differences between Galileo and GPS transmitted signals are shown and their impact on altimetric performance is carefully pinpointed, analysed and justified. Simulated cross-correlation altimetric waveforms are evaluated and the performance analysed by means of an analytical model for the evaluation of height measurement precision. The analysis shows that, thanks to the unique features in terms of bandwidth, TX power and modulation schemes, a GNSS-R altimeter based on Galileo signals-in-space could easily meet the requirements on precision for mesoscale ocean altimetry.
An examination of the “full‐wave” method for rough surface scattering in the case of small roughness (1991)

We examine the accuracy of Bahar's “full‐wave” method for rough surface scattering in the case of small roughness. The specific problem examined is scattering from one‐dimensional rough surfaces assuming the Dirichlet boundary condition. This corresponds to scattering of horizontally polarized electromagnetic waves from perfectly conducting one‐dimensional surfaces. By one dimensional surfaces we mean surfaces with constant height in the direction perpendicular to the incident wave direction. Our main result is that full‐wave predictions for the normalized bistatic radar cross section are found to disagree substantially with first‐order perturbation theory when the latter is known to be accurate through comparison with exact integral equation studies. This disagrees with Bahar's conclusions. The full‐wave predictions for the normalized radar cross section were computed using a Monte Carlo method and also by averaging formally; the two methods show excellent agreement. For the examples discussed in the paper, the full‐wave prediction agrees closely with the Kirchhoff approximation result, though the Kirchhoff approximation is not accurate away from the specular direction for these cases. In fact, for the special case of backscattering with shadowing neglected, the full‐wave predictions are shown to agree exactly with the Kirchhoff approximation results, independent of surface roughness properties. We examine Bahar's analytic argument for the reduction of full‐wave theory to perturbation theory and show that it is based on an inconsistent expansion in small surface height. When the small height expansion is done consistently, the full‐wave prediction does not reduce to first‐order perturbation theory. Finally, we consider the computational procedure given by Bahar to reduce the numerical effort in evaluating full‐wave theory. We find that numerical results obtained via this procedure approximately coincide with numerical results from first‐order perturbation theory for sufficiently small surface heights and slopes. This may at first seem confusing in light of our other findings. However, we show that certain simplifying assumptions in Bahar's computational procedure change the numerical results significantly from those computed from full‐wave theory without such assumptions. Thus these assumptions are not acceptable approximations for full‐wave theory, and results based on them should not be considered valid results of full‐wave theory.
A new and general synthesis of polycyclic .gamma.-lactones by double annulation (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA new and general synthesis of polycyclic .gamma.-lactones by double annulationE. J. Corey and Myung Chol KangCite this: J. Am. Chem. Soc. 1984, 106, 18, 5384–5385Publication Date (Print):September 1, 1984Publication History Published online1 May 2002Published inissue 1 September 1984https://doi.org/10.1021/ja00330a076Request reuse permissionsArticle Views2093Altmetric-Citations134LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (302 KB) Get e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts