gebhart/patrepeval huggingface dataset:
Chemical processing in high-pressure aqueous environments. 2. Development of catalysts for gasification (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChemical processing in high-pressure aqueous environments. 2. Development of catalysts for gasificationDouglas C. Elliott, L. John Sealock Jr., and Eddie G. BakerCite this: Ind. Eng. Chem. Res. 1993, 32, 8, 1542–1548Publication Date (Print):August 1, 1993Publication History Published online1 May 2002Published inissue 1 August 1993https://pubs.acs.org/doi/10.1021/ie00020a002https://doi.org/10.1021/ie00020a002research-articleACS PublicationsRequest reuse permissionsArticle Views1199Altmetric-Citations236LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
High moisture resistant electroactive composites (1992)

Abstract The drive for a rapid development of composite materials stems from the need for a combination of desirable properties that often cannot be obtained in singlephase materials. Electroactive composites consisting of a ferroelectric ceramic powder and an electrically inert polymer phase offer substantial advantages for the design and production of special purpose transducers. 0-3 composites have been prepared using a silicone rubber as the three dimensional inert polymer matrix. The poling characteristics are described along with the moisture uptake properties and its effect on piezoelectric voltage sensitivity and dielectric loss factor (tan(δ)). Comparisons are made where possible with an epoxy resin composite
Fatigue design of suspension components by latest interaction of numerical an experimental structural durability methods (2009)

S.1207-1214
Specialization in pyramidal cell structure in the sensory‐motor cortex of the Chacma baboon (Papio ursinus) with comparative notes on macaque and vervet monkeys (2005)

The systematic study of pyramidal cell structure has revealed new insights into specialization of the phenotype in the primate cerebral cortex. Regional specialization in the neuronal phenotype may influence patterns of connectivity and the computational abilities of the circuits they compose. The comparative study of pyramidal cells in homologous cortical areas is beginning to yield data on the evolution and development of such specialized circuitry in the primate cerebral cortex. Recently, we have focused our efforts on sensory-motor cortex. Based on our intracellular injection methodology, we have demonstrated a progressive increase in the size of, the branching structure in, and the spine density of the basal dendritic trees of pyramidal cells through somatosensory areas 3b, 1, 2, 5, and 7 in the macaque and vervet monkeys. In addition, we have shown that pyramidal cells in premotor area 6 are larger, more branched, and more spinous than those in the primary motor cortex (MI or area 4) in the macaque monkey, vervet monkey, and baboon. Here we expand the basis for comparison by studying the basal dendritic trees of layer III pyramidal cells in these same sensory-motor areas in the chacma baboon. The baboon was selected because it has a larger cerebral cortex than either the macaque or vervet monkeys; motor cortex has expanded disproportionately in these three species; and motor cortex in the baboon reportedly has differentiated to include a new cortical area not present in either the macaque or vervet monkeys. We found, as in monkeys, a progressive increase in the morphological complexity of pyramidal cells through areas 3b, 5, and 7, as well as from area 4 to area 6, suggesting that areal specialization in microcircuitry was likely to be present in a common ancestor of primates. In addition, we found subtle differences in the extent of the interareal differences in pyramidal cell structure between homologous cortical areas in the three species.
Phase II Study of TRIplet combination Nivolumab (N) with Dabrafenib (D) and Trametinib (T) (TRIDeNT) in patients (pts) with PD-1 naïve or refractory BRAF-mutated metastatic melanoma (MM) with or without active brain metastases. (2021)

9520 Background: Targeted therapies (TT) &amp; immunotherapies (IMT) have improved survival for pts with BRAF V600 mutated stage IV MM, however many pts still progress and ultimately die from their disease. Preclinical data support the rationale for combining TT and IMT, but trials evaluating triplet combinations in IMT-naïve pts have reported mixed results. Notably, pts with untreated brain metastases (BM) were excluded from prior triplet trials and have a median PFS of 5.6 months when treated with TT. Further, there remains an unmet need for effective therapies for pts after IMT failure, as retrospective studies have reported short median PFS (5 mos) for TT in this setting. We hypothesized that N in combination with DT is safe and will demonstrate clinical activity in BRAF-mutated pts naïve or refractory to PD1 therapy and in pts with BM. Methods: We conducted a single arm phase II study (NCT02910700) of NDT in pts with BRAF-mutated, unresectable stg III or stg IV MM. Prior IMT was allowed, but prior BRAF/MEKi was not. Pts with untreated BM and asymptomatic or mildly symptomatic/requiring steroids were also allowed. Pts received 3mg/kg IV Q2wks of N (later amended to 480 mg IV Q4wks), 150mg PO BID of D and 2mg PO QD of T, all starting on Day 1. The primary objective was to determine safety and efficacy (ORR by RECIST 1.1). Monitoring for safety and futility using Bayesian stopping rules was performed. Longitudinal tissue and blood samples were collected to perform correlative analyses. Results: Following a 6 pt safety run-in with no observed DLTs, 27 pts were treated w NDT. 17 pts were PD1 refractory, 10 were PD-1 naïve. 10 of these 27 pts had a history or presence of BM, including active BM. Median follow up was 18.4 months (range 3.2-45.9). ORR in 26 evaluable pts was 92% (3 CR, 21 PR). Among the PD1 refractory pts evaluable for response (n = 16), ORR was 88% (2 CRs, 12 PR). All 10 evaluable PD-1 naïve pts achieved a response. 4 of 7 evaluable pts w BM achieved an intracranial response (57%), including 2 CRs. The median PFS for all pts was 8.5mos (8.5mos in PD1 naïve pts, 8.2mos in PD1 refractory pts). Median PFS for pts without BM was 8.5mos, 8.0 mos for those with BM. Median OS for all pts was not reached, and no statistically significantly difference in OS by PD1 exposure or presence of BM. 78% of pts experienced treatment related grade 3/4 AEs and 6 pts (22%) discontinued all 3 drugs due to toxicities. Conclusions: NDT at full doses of all 3 agents has a toxicity profile consistent with previously reported triplet combinations and shows promising clinical activity in pts with IMT refractory disease and with BM. There were no significant differences in outcomes between pts with and without BM. Translational studies to delineate predictors and mechanisms of response and resistance are ongoing. Clinical trial information: NCT02910700.
Renally Excretable Silver Telluride Nanoparticles as Contrast Agents for X-ray Imaging (2022)

The use of nanoparticles in the biomedical field has gained much attention due to their applications in biomedical imaging, drug delivery, and therapeutics. Silver telluride nanoparticles (Ag<sub>2</sub>Te NPs) have been recently shown to be highly effective computed tomography (CT) and dual-energy mammography contrast agents with good stability and biocompatibility, as well as to have potential for many other biomedical purposes. Despite their numerous advantageous properties for diagnosis and treatment of disease, the clinical translation of Ag<sub>2</sub>Te NPs is dependent on achieving high levels of excretion, a limitation for many nanoparticle types. In this work, we have synthesized and characterized a library of Ag<sub>2</sub>Te NPs and identified conditions that led to 3 nm core size and were renally excretable. We found that these nanoparticles have good biocompatibility, strong X-ray contrast generation, and rapid renal clearance. Our CT data suggest that renal elimination of nanoparticles occurred within 2 h of administration. Moreover, biodistribution data indicate that 93% of the injected dose (%ID) has been excreted from the main organs in 24 h, 95% ID in 7 days, and 97% ID in 28 days with no signs of acute toxicity in the tissues studied under histological analysis. To our knowledge, this renal clearance is the best reported for Ag<sub>2</sub>Te NP, while being comparable to the highest renal clearance reported for any type of nanoparticle. Together, the results herein presented suggest the use of GSH-Ag<sub>2</sub>Te NPs as an X-ray contrast agent with the potential to be clinically translated in the future.
Analytical Solution for Subsurface Gas Flow to a Well Induced by Surface Pressure Fluctuations (2002)

A simple analytical model is presented for predicting subsurface gas flow to a vadose-zone well in response to atmospheric pressure fluctuations (barometric pumping). The effective radial permeability (kr) in the vicinity of the well is determined during model calibration using less than two weeks worth of data. By combining the flow solution with a solution for the vertical gas pressure, only atmospheric pressure data are required to predict the induced flow through a well. The ability to quantitatively predict naturally induced flow in vadose-zone wells by simple and inexpensive measurements is invaluable for systems using barometric pumping for remediation.
ChemInform Abstract: METAL‐ASSISTED TERPENOID SYNTHESIS. I. REGIOSELECTIVE ISOPRENE INSERTION INTO O AN ALLYL‐MAGNESIUM BOND AND THE APPLICATIONS TO SYNTHESIS OF NATURAL TERPENOIDS (1976)

Abstract In einer Insertionsreaktion setzen sich die Mg‐chloride (I) mit einer Isopren (II)‐Einheit in Gegenwart von katalytischen Mengen der Ti‐Verbindung (III) zu den Grignard‐ Verbindungen (IV) um; insitu‐Folgereaktionen von (IVa) bzw. (IVb) liefern die Diene (V) bzw. die Säure (VI).
Table S2 from Immune Gene Expression Is Associated with Genomic Aberrations in Breast Cancer (2023)

&lt;p&gt;Gene memberships of the 13 immune metagenes.&lt;/p&gt;
Intracellular catalysis of disulfide bond formation by the human sulfhydryl oxidase, QSOX1 (2007)

The discovery that the flavoprotein oxidase, Erv2p, provides oxidizing potential for disulfide bond formation in yeast, has led to investigations into the roles of the mammalian homologues of this protein. Mammalian homologues of Erv2p include QSOX (sulfhydryl oxidases) from human lung fibroblasts, guinea-pig endometrial cells and rat seminal vesicles. In the present study we show that, when expressed in mammalian cells, the longer version of human QSOX1 protein (hQSOX1a) is a transmembrane protein localized primarily to the Golgi apparatus. We also present the first evidence showing that hQSOX1a can act in vivo as an oxidase. Overexpression of hQSOX1a suppresses the lethality of a complete deletion of ERO1 (endoplasmic reticulum oxidase 1) in yeast and restores disulfide bond formation, as assayed by the folding of the secretory protein carboxypeptidase Y.
High‐Rate Continuous Synthesis of Nanocrystalline Perovskites and Metal Oxides in a Colliding Vapor Stream of Microdroplets (2013)

A high‐rate, continuous synthesis of functional nanomaterials using a home engineered reactor is reported. The reactor is able to produce low‐cost, kilogram‐scale BaTiO 3 nanopowders with a nanocrystalline particle size less than 30 nm at mild temperatures (&lt;100 °C) and ambient pressure. Nebulization and collision of warm microdroplets (60–80 °C) of Ba(OH) 2 and Ti(O‐nBu) 4 very quickly result in total hydrolysis and subsequent conversion to BaTiO 3 , yielding 1.3 kg/day of high purity, highly crystalline nanoparticles (25–30 nm). This synthesis procedure also enables high‐rate production of TiO 2 anatase (2.9 kg/day). It therefore provides a general platform for processing and scaling up of functional inorganic nanomaterials under very mild conditions.
Influence of gas desorption in a safety relief valve undergoing cavitation (2019)

In this study, the characterization of the flow through a safety relief valve (SRV) is performed in presence of cavitation and gas desorption. For this purpose, a transparent safety relief valve model is used on an experimental facility in which the flow conditions (mass flow rate, fluid temperature, and pressure upstream and downstream the valve) can be accurately monitored. For two different valve openings, the characteristic curves are measured while flow visualization is performed on the transparent model. The results show that choked flow conditions are reached only for the smallest valve opening, with a remarkable repeatability. In order to take into consideration the gas saturation level of the working fluid, the vacuum system used to adjust the pressure downstream is also used for gas desorption by storing the liquid under vacuum conditions, a process known as vacuum degasification. In saturated liquids the evolved gas bubbles modify the flow properties, such as the speed of sound, and this may have an influence in the cavitation inception and the occurrence of choked flow. This study proves that gas saturated water in standard conditions (atmospheric pressure and 293 K) has the same behavior that fully deaerated water, both under the same cavitating conditions. It is thus not necessary to take the saturation level of the liquid into account when in standard conditions. The same is not expected in pressurized saturated liquids, which is currently under study.
Heat-Extraction Technique for Recovery of Potato Tuberworm Larvae from Potato Tubers (1969)

Journal Article Heat-Extraction Technique for Recovery of Potato Tuberworm Larvae from Potato Tubers Get access G. R. Platner, G. R. Platner Department of Biological Control, University of California, Citrus Research Center and Agricultural Experiment Station, Riverside Search for other works by this author on: Oxford Academic PubMed Google Scholar P. D. Greany, P. D. Greany Department of Biological Control, University of California, Citrus Research Center and Agricultural Experiment Station, Riverside Search for other works by this author on: Oxford Academic PubMed Google Scholar E. R. Oatman E. R. Oatman Department of Biological Control, University of California, Citrus Research Center and Agricultural Experiment Station, Riverside Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Economic Entomology, Volume 62, Issue 1, 1 February 1969, Pages 271–272, https://doi.org/10.1093/jee/62.1.271 Published: 01 February 1969 Article history Accepted: 28 October 1968 Published: 01 February 1969
Trust-preserving set operations (2005)

We describe a method for performing trust-preserving set operations by untrusted parties. Our motivation for this is the problem of securely reusing content-based search results in peer-to-peer networks. We model search results and indexes as data sets. Such sets have value for answering a new query only if they are trusted. In the absence of any system-wide security mechanism, a data set is trusted by a node a only if it was generated by some node which is trusted by a. Our main contributions are a formal definition of the problem as well as an efficient scheme that solves this problem by allowing untrusted peers to perform set operations on trusted data sets while also producing unforgeable proofs of correctness. This is accomplished by requiring trusted nodes to sign appropriately-defined digests of generated sets; each such digest consists of an RSA accumulator and a Bloom filter. The scheme is general, and has other applications as well. We give an analysis demonstrating the low overhead of the scheme, and we include experimental data which confirm the analysis.
Circulating microRNAs in Plasma as Predictive Biomarkers for Parkinson's Disease: a New Paradigm (2014)

Parkinsons disease (PD) is a complex neurological disorder caused by progressive loss of dopaminergic neurons, leading to motor, cognitive, and gastro-intestinal dysfunctions. Due to the subtle nature of its motor symptoms which current clinical diagnosis is majorly based on, neurodegeneration has reached a relatively advanced stage by the time of diagnosis. Here, we identify and develop a panel of circulating microRNA (miRNAs) in plasma as biomarkers for PD. The biomarkers achieve the predictive power of 91% sensitivity and 100% specificity.
Effect of Surface Roughness Induced by Laser Powder Bed Fusion Additive Manufacturing in a Mini-Channel Heat Exchanger (2019)

Abstract The Inside-Out Ceramic Turbine (ICT) is a promising microturbine for aeronautics applications. To increase the cycle efficiency and reduce fuel consumption, microturbines must operate under the recuperated Brayton cycle. The addition of a heat exchanger (HEx) increases the weight of the engine and cancels out any fuel savings as compared to a non-recuperated turbine. For this reason, the requirements applied to HEx for aeronautic gas turbines are: low weight and volume, high effectiveness with a low pressure drop, capabilities to endure high pressure and temperature, and low cost. The Laser powder bed fusion (LPBF) opens a new design space for geometries that cannot be realized by conventional methods, but induces high surface roughness. This paper presents experimental and analytical studies of the influence of surface roughness on the performances of a 3D-printed, counterflow, mini-channel HEx, with 1% of the total mass flow rate of the ICT. Results showed that the friction and heat transfer are both increased in the the regime typically defined as laminar compared to the analytical results. The experimental results are in agreement with a 1D heat transfer model when using correlations for high-roughness values from the literature. LPBF is a promising method to manufacture gas turbine parts, but it is crucial to model and incorporate its manufacturing capacities in terms of precision and surface finish to enhance HEx heat transfer and potentially reduce mass.
Adjustment capacity in a monetary union: a DSGE evaluation of Poland and Slovakia (2010)

Once a country joins a monetary union, an efficient competitiveness channel is commonly considered to be the main substitute for the abandoned autonomous monetary and exchange rate policy. This paper attempts to make an empirical assessment of how the price competitiveness of domestic producers stabilizes the Polish and Slovak economies in comparison to the real interest rate, that could potentially be procyclical in EMU. To address this issue, we revisit the econometric studies of weighting the Monetary Conditions Index (MCI-ratio) to explore the relative importance of the two channels. We apply the IS-curve approach and -- as opposed to previous MCI-ratio literature -- we build a small open economy DSGE framework to be estimated with classical forward-looking techniques (FIML). We compare the estimates and impulse-response functions for Poland and Slovakia, concluding that the latter country seems to be more capable of handling asymmetric demand shocks under the common monetary policy. At the same time, it remains more vulnerable to asymmetric cost-push shocks. Also, we examine the consequences of a permanent fall in the interest rates in the home economy after the accession to the monetary union. If there was a natural interest rate disparity of 1 percentage point in favour of the catching-up economy and agents expected a 30-year long period of closing this gap, our model would predict a terms of trade appreciation for both countries in question, whereby the required appreciation would be more pronounced for Poland than for Slovakia (9.9% and 2.6% respectively).
Enabling the Optimisation of the Primary Suspension with Passive Components for an Industrial Railway Vehicle Model (2018)

The use of inerters in the lateral suspension of railway vehicles has been proven, in recent studies using lumped mass models, to provide benefits to both track wear and passenger comfort. Validation of these enhancements using an industry standard simulation tool is essential if the railway industry is going to adopt this new piece of technology. The problems associated with this, however, come in the form of large numerical matrices, slow inversion times, and the inability to perform systematic investigations of candidate vibration absorber configurations. This paper proposes a Location Matrix method of simulation which enables the optimisation of interchangeable suspension networks within large dynamic systems. This method, which requires only the base M, C and K matrices, is validated on a simple system, and it is found that for railway vehicles, optimisations on semi-linearised models can be performed. Nonlinearities arising from the varying contact patch normal force mean that further research is needed before a full analysis can take place.
The Warranty of Habitability: A Bill of Rights for Homebuyers (1983)

Warranty of Habitability
ChemInform Abstract: Preparations and Sulfurization Reactions of (2,4‐Di‐tert‐butyl‐6‐ methoxyphenyl)phosphine and 1‐(2,4‐Di‐tert‐butyl‐6‐methoxyphenyl)‐2‐(2, 4,6‐tri‐tert‐butylphenyl)diphosphene. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Thermal infrared spectrometer MERTIS for the BepiColumbo Mission to Mercury (2017)

The MERTIS instrument is a thermal infrared imaging spectrometer onboard of ESA's cornerstone mission BepiColombo to Mercury. MERTIS will provide detailed information about the mineralogical composition of Mercury's surface layer by measuring the spectral emittance in the spectral range from 7-14 μm with a high spatial and spectral resolution. Furthermore MERTIS will obtain radiometric measurements in the spectral range from 7-40 μm to study the thermo-physical properties of the surface material. Under the lead of the German Aerospace Center DLR (Dep. Optical Information Systems, Berlin) a development model (DM) is in development which integrates all MERTIS sub-units of later flight models. With the DM the general design and performance goals of the system shall be investigated and verified. Besides a general overview about the instrument principles the following topics are addressed: Optics setup with a Three Mirror Anastigmatic (TMA) telescope and Offner Spectrometer, Manufacturing techniques for the robust and high precision optics and Radiometer Concept and Design