gebhart/patrepeval huggingface dataset:
Utilization of polyethylene terephthalate (PET) in bituminous mixture for improved performance of roads (2017)

Plastic bottle for recycling can be found from the household waste stream, and most of them are made from Polyethylene Terephthalate. In this research, PET is utilized to explore the potential prospects to upgrade asphalt mixture properties. The objectives include deciding the best measure of PET to be used. For experimental, Marshall mix design was utilized to determine the ideal bitumen binder content and to test the modified mixture properties. The samples were created per the requirement for aggregate course wearing (ACW14) using the Standard Specification of Road Work (SSRW) in Malaysia. 20 samples were utilized to determine the binder content, and 30 samples were used to research the impact of modifying asphalt mixtures. 2%, 5%, 10%, 15% and 20% of PET by weight of the optimum binder content (4.8%) were tested. Optimum PET content is 10%, and the result shows a good stability with 16.824kN, 2.32g/cm3 bulk density, void filled with bitumen (VFB) with 71.35%, flow with 3.2248mm, air void (AV) with 4.53%, and void of mineral aggregate (VMA) with 15.15%. The outcomes showed that PET modifier gives better engineering properties. Therefore, 10% of PET by the weight of binder content was suggested as the best amount of the modifier.
Method for gap formation in liquid crystal displays (2000)

A new method for making displays with well defined thickness of the liquid crystal layer is described. This method is capable of making rigid displays with variable gap and is distinguished by simplicity and reliability. Display color variation with the observation angle is studied for different electrooptic effects.
Supporting teams to optimize function and independence in Veterans: a multi-study program and mixed methods protocol (2018)

NCT03300336 Registered September 28, 2017, NCT03474380 Registered March 15, 2018.
Aluminum Nanoplatelet Electrodeposition in AlCl 3 –1-Ethyl-3-Methylimidazolium Chloride–Urea Melts (2022)

The electrodeposition behavior of Al nanoplatelets, which are two-dimensional Al metal thin layer deposits, was investigated in five types of Lewis acidic 60– x –(40− x ) [0 ≤ x ≤ 40] mol% AlCl 3 –1-ethyl-3-methylimidazolium chloride ([C 2 mim]Cl)–urea room-temperature melts. Al nanoplatelets were obtained in 60–10–30 and 60–0–40 mol% AlCl 3 –[C 2 mim]Cl–urea melts. X-ray diffraction measurements revealed that these Al nanoplatelets were oriented in the 111 direction. The formation of this anomalous Al nanoplatelets was analyzed using the operando digital microscope observation technique with our original air-tight electrochemical cell. We succeeded in video recording of the entire formation of Al nanoplatelets in the 60–0–40 mol% AlCl 3 –[C 2 mim]Cl–urea melt. Considering these results and electrode reactions involved in the Al deposition process, the electrodeposition behavior of the Al nanoplatelet formation could be attributed to the adequate quantities of free urea molecules generated during the electrode reaction and their specific adsorption onto the (111) Al crystal plane. The applied current density was an important key factor for the electrodeposition of the Al nanoplatelets in the AlCl 3 –[C 2 mim]Cl–urea melt. Al nanoplatelets were produced at low applied current densities smaller than −5.0 mA cm −2 . The Al nanoplatelets became larger at lower applied current densities.
Synthesis of 3-deazaneplanocin A, a powerful inhibitor of S-adenosylhomocysteine hydrolase with potent and selective in vitro and in vivo antiviral activities (1989)

The neplanocin A analogue 3-deazaneplanocin A (2b) has been synthesized. A direct SN2 displacement on the cyclopentenyl mesylate 3 by the sodium salt of 6-chloro-3-deazapurine afforded the desired regioisomer 4 as the major product. After deprotection, this material was converted to 3-deazaneplanocin A in two steps. X-ray crystallographic analysis confirmed the assigned structure. Consistent with its potent inhibition of S-adenosylhomocysteine hydrolase, 3-deazaneplanocin A displayed excellent antiviral activity in cell culture against vesicular stomatitis, parainfluenza type 3, yellow fever, and vaccinia viruses. Antiviral activity was also displayed in vivo against vaccinia virus by using a mouse tailpox assay. The significantly lower cytotoxicity of 3-deazaneplanocin A, relative to its parent compound neplanocin A, may be due to its lack of conversion to 5'-triphosphate and S-adenosylmethionine metabolites.
Profinite posets (1972)

The class of ordered topological spaces which are projective limits of finite partially ordered sets (equipped with the restriction of the product of the discrete topologies) is shown to coincide with the class of compact totally order-disconnected ordered topological spaces. Hence this is another category of spaces equivalent to the category of distributive lattices with zero and unit.
The impact of fiscal policy and inflation on national saving. A reply (2013)

The article serves as a response to Nicola Rossi’s critique of the authors’ previous work on fiscal policy and national savings in Italy. The authors reaffirm their previous finding that deficits have indeed reduced national savings and in particular make two points. First, contrary to his assertions, Rossi’s evidence is inconsistent with the Ricardian Equivalence Proposition. Second, this failure becomes even more apparent if one relies on the updated formulation and improved data underlying the more recent contribution of Modigliani and Jappelli (1987). JEL: E31, E62
Foreign Body Reaction to Meshes Used for the Repair of Abdominal Wall Hernias (1999)

Inflammation around alloplastic materials used to repair defects in the abdominal wall persists for many years. There was evidence of long term wound complications as a result of persistent foreign body reactions. Further studies are required to evaluate the long term tissue response to these materials.
Supplementary Figure 3 from Lack of Correlation between p53-Dependent Transcriptional Activity and the Ability to Induce Apoptosis among 179 Mutant p53s (2023)

Supplementary Figure 3 from Lack of Correlation between p53-Dependent Transcriptional Activity and the Ability to Induce Apoptosis among 179 Mutant p53s
Iron-Based Catalysts with Exceptionally High Activities and Selectivities for Oligomerization of Ethylene to Linear α-Olefins (1998)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTIron-Based Catalysts with Exceptionally High Activities and Selectivities for Oligomerization of Ethylene to Linear α-OlefinsBrooke L. Small and Maurice BrookhartView Author Information Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-3290 Cite this: J. Am. Chem. Soc. 1998, 120, 28, 7143–7144Publication Date (Web):July 7, 1998Publication History Received20 April 1998Published online7 July 1998Published inissue 1 July 1998https://doi.org/10.1021/ja981317qCopyright © 1998 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views5543Altmetric-Citations602LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (63 KB) Get e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Aromatic compounds,Catalysts,Hydrocarbons,Oligomers,Selectivity Get e-Alerts
PV output variability modeling using satellite imagery. (2010)

High frequency irradiance variability measured on the ground is caused by the formation, dissipation, and passage of clouds in the sky. If we can identify and associate different cloud types/patterns from satellite imagery, we may be able to predict irradiance variability in areas lacking sensors. With satellite imagery covering the entire U.S., this allows for more accurate integration planning and power flow modeling over wide areas. Satellite imagery from southern Nevada was analyzed at 15 minute intervals over a year. Methods for image stabilization, cloud detection, and textural classification of clouds were developed and tested. High Performance Computing parallel processing algorithms were also investigated and tested. Artificial Neural Networks using imagery as inputs were trained on ground-based measurements of irradiance to model the variability and were tested to show some promise as a means for predicting irradiance variability.
Shaking Acoustic Spectral Sub-bands Can Better Regularize Learning in Affective Computing (2018)

In this work, we investigate a recently proposed regularization technique based on multi-branch architectures, called Shake-Shake regularization, for the task of speech emotion recognition. In addition, we also propose variants to incorporate domain knowledge into model configurations. The experimental results demonstrate: $1)$ independently shaking sub-bands delivers favorable models compared to shaking the entire spectral-temporal feature maps. $2)$ with proper patience in early stopping, the proposed models can simultaneously outperform the baseline and maintain a smaller performance gap between training and validation.
AIE-active luminogens as highly efficient free-radical ROS photogenerator for image-guided photodynamic therapy (2022)

Image-guided photodynamic therapy (PDT) can realize highly precise and effective therapy <i>via</i> the integration of imaging and therapy, and has created high requirements for photosensitizers. However, the PDT modality usually utilizes conventional type II photosensitizers, resulting in unsatisfactory imaging and therapeutic outcomes due to aggregation-caused quenching (ACQ), "always on" fluorescence and strong oxygen dependence. Herein, we report the type I-based aggregation-induced emission (AIE) photosensitizer TCM-CPS with low oxygen dependence, near-infrared (NIR) emission and "off-on" fluorescence; in particular, it produces more reactive oxygen species (ROS) than commercially available Chlorin e6 and Rose Bengal. In the rational design of the AIE-based photosensitizer TCM-CPS, the strongly electron-donating carbazole unit and π-thiophene bridge distinctly extend the emission wavelength and decrease the autofluorescence interference in bio-imaging, and the hydrophilic pyridinium salt group guarantees good molecular dispersion and maintains the fluorescence-off state in the aqueous system to decrease the initial fluorescence background. Moreover, the strong donor-π-acceptor (D-π-A) character in TCM-CPS greatly separates the HOMO-LUMO distribution, enhancing the ROS generation, and TCM-CPS was constructed as a type I photosensitizer with the assistance of strong intramolecular charge transfer in the electron-rich anion-π<sup>+</sup> structure. Based on its favorable hydrophilicity and photosensitivity, TCM-CPS was found to be a highly efficient free-radical ROS photogenerator for both visualizing cells using light-up NIR fluorescence and efficiently killing cancer cells upon light irradiation. The positively charged TCM-CPS could quickly bind to bacteria <i>via</i> electrostatic interactions to provide a light-up signal and kill bacteria at a low concentration. In the PDT treatment of bacteria-infected mice, the mice exhibited accelerated wound healing with low wound infection. Thus, the AIE-based type I photosensitizer TCM-CPS has great potential to replace commercially available photosensitizers in the image-guided PDT modality for the treatment of cancer and bacterial infection.
<title>Quantum efficiency measurement on a CCD detector in the 0.3- to 1100-nm spectral region</title> (1997)

The performances of a CCD have been evaluated in a very wide spectral region, which comprises near IR, visible, near and far UV, EUV and soft x-ray spectral regions. The CCD detector is a back illuminated one, 512 by 512 format, 24 by 24 micrometer squared pixel. The performed measurements consist mainly on the determination of the quantum efficiency in the 0.3 - 1100 nm (4.5 keV - 1 eV) spectral region. Three different experimental setup have been used: a Czerny-Turner monochromator for the 1100 - 250 nm region, a Johnson-Onaka monochromator for the 250 - 30 nm region, and a grazing incidence Rowland monochromator for the 25 - 0.3 nm region. The tested CCD exhibits high values of quantum efficiency in the analyzed spectral range, representing a very useful detector of radiation in the extended optical domain.
Nursing implications in the management of superficial bladder cancer. (1996)

Intravesical therapy is preferred over systemic treatment for superficial bladder cancer. Four agents commonly used are thiotepa, doxorubicin, mitomycin, and bacille Calmette-Guérin. A thorough understanding of the unique methods involved in the instillation of these drugs and the special patient-management procedures associated with their use is critical for nursing personnel. Occupational Safety and Health Administration guidelines exist to ensure safe handling of intravesical agents. Nurses are urged to take precautions to limit their exposure to these potentially hazardous drugs. For example, bacille Calmette-Guérin, a live virus, represents a biohazard and extreme caution is required in all aspects of handling, particularly in its disposal. Because of the potential complications associated with intravesical therapy, a significant responsibility of the nurses who administer it is patient education. Patients need to know what to expect during the treatment process as well as how to recognize the signs and symptoms of complications. In addition to gaining a thorough knowledge of the techniques involved in the intravesical treatment of superficial bladder cancer, nurses can also serve their patients better by using sensitive to the unique psychosocial problems they face.
Untersuchung von Therapieergebnissen durch DNA-Methyltransferase-Inhibitoren bei Patienten mit Myelodysplastischen Syndromen und Akuten Myeloischen Leukämien (2014)

Die Behandlungsmodalitaten fur Patienten mit Myelodysplastischen Syndromen beschrankten sich bisher im Wesentlichen auf supportive Therapien und bei jungeren Patienten auf die intensive Chemotherapie und allogene Stammzelltransplantation. Fur viele Patienten aber kommt die allogene Stammzelltransplantation aufgrund ihres Alters und der bestehenden Komorbiditaten nicht in Frage. Alternativ steht seit einigen Jahren die epigenetische Therapie mit Decitabine und 5‘-Azacytidine zur Verfugung. In der vorliegenden Arbeit sind die Therapieergebnisse von 102 Patienten mit MDS und AML unter einer Therapie mit den DNA-Methyltransferase-Inhibitoren Decitabine und 5‘-Azacytidine untersucht worden: Bei 39% aller Patienten wurde ein Ansprechen im Sinne von hamatologischen Remissionen erzielt. Das Gesamtuberleben lag im Median bei 18,5 Monaten und die Zeitspanne ab Therapiebeginn bis Tod betrug 9,2 Monate im Median. Unbeantwortet bleiben Fragen nach pradiktiven Faktoren fur das Ansprechen auf eine Therapie mit Decitabine und 5‘-Azacytidine, sowie nach Kombinationstherapien, beispielsweise mit HDAC-Inhibitoren wie Valproinsaure. Auch bleibt weiterhin unklar, welche Patienten es sind, die auf eine solche Therapie ansprechen. Auch wenn eine Heilung nicht erreicht werden kann, sind die Verbesserung der Lebensqualitat und Verlangerung des Uberlebens in jedem Fall anzustrebende Therapieziele. 5´-Azacytidine und Decitabine kommen somit als effektive Therapieoptionen bei, vor allem alteren Patienten infrage, die durch die Verbesserung von klinischen oder hamatologischen Parametern und durch ein mildes Nebenwirkungsprofil sowie abnehmenden Transfusionsbedarf diese Therapieziele erfullen.
Nutritional Epidemiology (2012)

Abstract This book is about the complex relationships between diet and risks of important diseases, such as cancer and cardiovascular disease. The book starts with an overview of research strategies in nutritional epidemiology—still a relatively new discipline that combines the vast knowledge compiled by nutritionists during this century with the methodologies developed by epidemiologists to study the determinants of diseases with multiple etiologies and long latent periods. A major section is devoted to the methods of dietary assessment using data on food intake, biochemical indicators of diet, and measures of body composition and size. The reproducibility and validity of each approach and the implications of measurement error are considered in detail. The analysis, presentation, and interpretation of data from epidemiologic studies of diet and disease are explored in depth. Particular attention is paid to the important influence of total energy intake on findings in such studies. To illustrate methodological issues in nutritional epidemiology, the relationships of dietary factors to the incidence of lung and breast cancer, heart disease, and birth defects are examined in depth. This new edition, in addition to updating existing chapters, includes new chapters on assessment of physical activity, nutrition, and genetic epidemic ology, and the role of nutritional epidemiology in policy.
“A posteriori” modification of carbosilane dendrimers and dendrons: their activation in core and branch positions (2005)

The introduction of phenyl groups at different points on carbosilane dendrimers allows their acidolytic conversion to highly reactive triflato groups which in turn are readily substituted by anionic nucleophiles. Core phenylated first-fourth generation dendrimers were synthesized from tri(allyl)phenylsilane by an alternating sequence of hydrosilylation and allylation steps. Similarly, carbosilane dendrimers containing phenyl-Si groups at the branching points and in the periphery were prepared from tetraallylsilane which was hydrosilylated with PhHSiCl2. Reaction of the phenylated dendrimers with triflic acid in toluene cleanly gave the silyl triflate derivatives, provided that the correct stoichiometry of the reagents was used. In the presence of a large excess of triflic acid the SiMe3-end groups are slowly converted to SiMe2(OTf)-units. The proof of concept was provided by the fixation of a {Ph2PCH2} group using the lithiated diphenylphosphinomethanide Ph2PCH2Li, obtained by cleavage of Ph3SnCH2PPh2 with PhLi, as well as a lithiated ether-alcohol functionalized triphos derivative to the core of a third generation carbosilane dendrimer.
Complex multiple introductions drive fall armyworm invasions into Asia and Australia (2022)

Abstract The fall armyworm (FAW) Spodoptera frugiperda is thought to have undergone a rapid ‘west-to-east’ spread since 2016 when it was first identified in western Africa. Between 2018 and 2020, it was also recorded from South Asia (SA), Southeast Asia (SEA), East Asia (EA), and Pacific/Australia (PA). Population genomic analyses enabled the understanding of pathways, population sources, and gene flow in this notorious agricultural pest species. Using neutral single nucleotide polymorphic (SNP) DNA markers, we detected genome introgression that suggested most populations were overwhelmingly C- and R-strain hybrids. SNP and mitochondrial DNA markers identified multiple introductions that were most parsimoniously explained by anthropogenic-assisted spread, i.e., associated with international trade of live/fresh plants and plant products, and involved ‘bridgehead populations’ in countries to enable successful pest establishment in neighbouring countries. Distinct population genomic signatures between Myanmar and China do not support the ‘African origin spread’ nor the ‘Myanmar source population to China’ hypotheses. Significant genetic differentiation between populations from different Australian states supported multiple pathways involving distinct SEA populations. Our study identified Asia as a biosecurity hotspot and a FAW genetic melting pot, and demonstrated the use of genome analysis to disentangle preventable human-assisted pest introductions from unpreventable natural pest spread.
Genetic diversity of theCampylobactergenes coding immunodominant proteins (2000)

Three Campylobacter jejuni 72Dz/92 genes (cjaA (ompH1), cjaC (hisJ) and cjaD (omp18)) encoding immunodominant proteins are considered to be potential chicken vaccine candidates. The presence and conservation of cjaA, cjaC and cjaD genes among different Campylobacter clinical isolates were determined. The genes were detected in thirty Campylobacter strains using hybridization as well as Western blot analysis. However, PCR products of the predicted size were amplified only from ten out of thirty examined strains regardless of the employed primer pair. The nucleotide sequence of the C. jejuni 72Dz/92 genes was compared with the nucleotide sequences of their homologs cloned from other Campylobacter strains as well as with the whole genome sequence of C. jejuni NCTC 11168. The examined sequences revealed 0 to 16% divergence. Strain-dependent levels of divergence were observed. The polymorphism detected in cjaC was mainly within the 5' region of the gene, while the nucleotide substitutions in cjaA and cjaD are distributed uniformly along the whole genes. Most of the observed nucleotide substitutions occurred at the third base of the codons. This observation is consistent with the results of Western blot experiments.
Your core--- my problem? (panel session) (2001)

As the popularity of reusing existing designs--or Intellectual Property (IP)--continues to grow, design challenges escalate. The most time-consuming and critical part of IP design and reuse is verifying that it will work as it was designed to and as the user intends. Designers are pushing the limits of IP for new, distinctive and innovative applications. With this innovation come problems that need creative solutions. Product verification, for example, will become more and more important in ensuring the correctness of the design. Over the years, various solutions have come on the market, all seemingly useful, but none reducing the time or manpower it takes to verify the design. With designs becoming increasingly more complex with each new project and verification consuming up to 70 percent of a design cycle, something must be done to alleviate the bottleneck.
The anti-tumor immune response generated by radiation therapy may be limited by tumor cell adaptive resistance and can be circumvented by PD-L1 blockade (2014)

Meeting abstracts Radiation therapy (RT) plays a definitive part of anti-cancer therapy for the majority of common cancers but for many patients, metastatic disease and local recurrence are common and the outlook remains poor. New more effective RT combination approaches are urgently required that