gebhart/patrepeval huggingface dataset:
Downlink Scheduling over Markovian Fading Channels (2011)

We consider the scheduling problem in downlink wireless networks with heterogeneous, Markov-modulated, ON/OFF channels. It is well-known that the performance of scheduling over fading channels relies heavily on the accuracy of the available Channel State Information (CSI), which is costly to acquire. Thus, we consider the CSI acquisition via a practical ARQ-based feedback mechanism whereby channel states are revealed at the end of only scheduled users' transmissions. In the assumed presence of temporally-correlated channel evolutions, the desired scheduler must optimally balance the exploitation-exploration trade-off, whereby it schedules transmissions both to exploit those channels with up-to-date CSI and to explore the current state of those with outdated CSI. In earlier works, Whittle's Index Policy had been suggested as a low-complexity and high-performance solution to this problem. However, analyzing its performance in the typical scenario of statistically heterogeneous channel state processes has remained elusive and challenging, mainly because of the highly-coupled and complex dynamics it possesses. In this work, we overcome these difficulties to rigorously establish the asymptotic optimality properties of Whittle's Index Policy in the limiting regime of many users. More specifically: (1) we prove the local optimality of Whittle's Index Policy, provided that the initial state of the system is within a certain neighborhood of a carefully selected state; (2) we then establish the global optimality of Whittle's Index Policy under a recurrence assumption that is verified numerically for our problem. These results establish that Whittle's Index Policy possesses analytically provable optimality characteristics for scheduling over heterogeneous and temporally-correlated channels.
Bone morphogenetic protein-binding endothelial regulator of liver sinusoidal endothelial cells induces iron overload in a fatty liver mouse model (2016)

BMPER secretion by LSECs inhibits BMP-SMAD signaling in hepatocytes and further reduces hepcidin protein expression. These intrahepatic molecular interactions suggest a novel molecular basis of iron overload in NAFLD.
ChemInform Abstract: STUDIES ON NEW THIAMINE DERIVATIVES HAVING ANTICOCCIDIAL ACTIVITY PART 2, ANTICOCCIDIAL ACTIVITY‐STRUCTURE RELATIONS (1973)

Abstract Von ca. 20 vergleichend untersuchten, überwiegend neuen Thiaminderivaten besitzen insbesondere die Verbindungen (I)‐(III) anticoccidiale Wirksam = keit (Eimeria tenella), wobei die Verbindung (Ia) die weitaus größte Aktivität aufweist.
Impact of Previous Genetic Counseling and Objective Numeracy on Accurate Interpretation of a Pharmacogenetics Test Report (2021)

We found that numeracy had a significant impact on correct interpretation of PGx test reports. Because many individuals in the USA have low numeracy levels, it is extremely important that patients do not make their own medication management decision based on the test results and that they consult with their physicians about their PGx testing. The importance of consultation and discussion with providers about results should be emphasized on the test report.
Comparison between CT Colonography and Double-Contrast Barium Enema for Colonic Evaluation in Patients with Renal Insufficiency (2012)

In patients with renal insufficiency, CTC has a higher diagnostic yield and a marginally higher PPV for detecting colorectal neoplasia, despite a similar diagnostic yield for adenocarcinoma, and a lower rate of inadequate examinations as compared with DCBE.
S168 ASTM Standards for Residual Stress Measurement (2008)

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Voltammetric Mechanism of Multiion Detection with Thin Ionophore-Based Polymeric Membrane (2016)

The capability to detect multianalyte ions in their mixed solution is an important advantage of voltammetry with an ionophore-based polymeric membrane against the potentiometric and optical counterparts. This advanced capability is highly attractive for the analysis of physiological ions at millimolar concentrations in biological and biomedical samples. Herein, we report on the comprehensive response mechanisms based on the voltammetric exchange and transfer of millimolar multiions at a thin polymeric membrane, where an ionophore is exhaustively depleted upon the transfer of the most favorable primary ion, I(zI). With a new voltammetric ion-exchange mechanism, the primary ion is exchanged with the secondary favorable ion, J(zJ), at more extreme potentials to transfer a net charge of |zJ|/nJ - |zI|/nI for each ionophore molecule, which forms 1:nI and 1:nJ complexes with the respective ions. Alternatively, an ion-transfer mechanism utilizes the second ionophore that independently transfers the secondary ion without ion exchange. Experimentally, a membrane is doped with a Na(+)- or Li(+)-selective ionophore to detect not only the primary ion, but also the secondary alkaline earth ion, based on the ion-exchange mechanism, where both ions form 1:1 complexes with the ionophores to transfer a net charge of +1. Interestingly, the resultant peak potentials of the secondary divalent ion vary with its sample activity to yield an apparently super-Nernstian slope as predicted theoretically. By contrast, the voltammetric exchange of calcium ion (nI = 3) with lithium ion (nJ = 1) by a Ca(2+)-selective ionophore is thermodynamically unfavorable, thereby requiring a Li(+)-selective ionophore for the ion-transfer mechanism.
Design of low–loss saw filters employing distributed acoustic reflection transducers (1987)

Abstract As a means to reduce the loss in an SAW filter, the IDT (interdigital transducer) called the internal reflection‐type transducer has been studied extensively recently. This IDT is believed to be useful as a filter for video and broadband data transmission since it is simple in structure and has low loss over a broadband while its fabrication process and external circuit are simple. So far, the filter constructed with this IDT has had a large ripple in the passband due to a large spurious reflection. To alleviate this problem, a new distributed acoustic reflection transducer is proposed as an internal reflection type IDT in which suppression of the unwanted spurious reflection is possible over a broad frequency range. Next, the operation mechanism of this IDT is investigated and a first‐order design method is presented. It is pointed out that a low‐loss filter with an insertion loss less than 10 dB and spurious reflection suppressed by more than 45 dB can be realized with this IDT over a broad frequency range.
Data-driven Analysis of TRP Channels in Cancer: Linking Variation in Gene Expression to Clinical Significance. (2016)

Our data-driven approach demonstrates that the variation in the expression of TRP channel genes is manifested across various human cancer types and genes, for certain TRP channels have strong predictive diagnostic and prognostic potential.
Supplementary Dataset 4 from Alkylation Sensitivity Screens Reveal a Conserved Cross-species Functionome (2023)

&lt;p&gt;XLS file - 615K, Fourth group of genes from the siRNA screen analyzed for gene enrichment using selection criteria of a p-value less than 0.05 and a viability ratio in the lowest 10%&lt;/p&gt;
Electron Spin Resonance Studies of Mn(+2), Gd(+3) and Cu(+2) in Chalcogenide Glasses ($Al_2S_3-La_2S_3$ System) (2002)

The chalcogenide glass (ALS, ) was prepared by melting a stoichiometric mixture of aluminum powder and under atmosphere at . Glasses containing 0.1-0.1% of and were also prepared. The characteristic features of the ESR spectra for the transition metal containing ALS glasses are interpreted.
A New Algorithm for Rachford-Rice for Multiphase Compositional Simulation (2010)

Summary Flash calculations for use in compositional simulation are more difficult and time-consuming as the number of equilibrium phases increases beyond two. Because of its complexity, many simulators do not even attempt to incorporate three or more hydrocarbon phases, even though such cases are important in many low-temperature gasfloods or for high temperatures where hydrocarbons can partition into water. Multiphase flash algorithms typically use successive substitution (SS) followed by Newton's method. For NP-phase flash calculations, (NP–1) Rachford-Rice (RR) equations are solved in every iteration step in SS and, depending on the choice of independent variables, in Newton's method. Solution of RR equations determines both compositions and amounts of phases for a fixed overall composition and set of K-values. A robust algorithm for RR is critical to obtain convergence in multiphase compositional simulation and has not been satisfactorily developed, unlike the traditional two-phase flash. In this paper, we develop an algorithm for RR equations for multiphase compositional simulation that is guaranteed to converge to the correct solution independent of the number of phases for both positive and negative flash calculations. We derive a function whose gradient vector consists of RR equations. This correct solution to the RR equations is formulated as a minimization of the nonmonotonic convex function using the independent variables of (NP–1) phase mole fractions. The key to obtaining a robust algorithm is that we specify nonnegative constraints for the resulting equilibrium phase compositions, which are described by a very small region with no poles. The minimization uses Newton's direction with a line-search technique to exhibit superlinear convergence. We show a case in which a previously developed method cannot converge while our algorithm rapidly converges in a few iterations. We implement the algorithm both in a standalone flash code and in UTCOMP (Chang et al. 1990), a multiphase compositional simulator, and show that the algorithm is guaranteed to converge when a multiphase region exists as indicated by stability analysis.
Er3+- Yb3+co-doped phosphate glass optical fiber for application at 1.54 microns (2006)

We present current work developed at INO on phosphate glass optical fiber for laser and amplifier applications at 1.54 microns. Core and cladding glasses were fabricated by a multi-components melting process which gave an uniform refractive index core profile. Rod-in-tube method under Argon atmosphere was used to fabricate optical fibers. The effect of nitrogen atmosphere on hydroxyl groups OH<sup>-</sup> during glass melting was studied. The absorption coefficient calculated at 3.42 &#956;m was found to be lower than 0.5 cm<sup>-1</sup> which corresponds to less than 70 ppm OH<sup>-</sup>. Absorption and emission cross sections were calculated at 1534 nm. Fabrication process allowed us to decrease background losses of core Er<sup>3+</sup> - Yb<sup>3+</sup> co-doped fiber between 0.02 and 0.04 dB/cm. Laser power was measured at 1563 nm and a 26% slope efficiency was achieved with a 22 cm-long single-clad fiber co-doped with 1.1 wt% in Er<sup>3+</sup> and 11.1 wt% in Yb<sup>3+</sup>. For the same fiber, an internal gain was found to be 20 dB at 1536 nm for a 5-cm-long fiber.
Membrane-anchored growth factor, HB-EGF, on the cell surface targeted to the inner nuclear membrane (2008)

Heparin-binding EGF-like growth factor (HB-EGF) is synthesized as a type I transmembrane protein (proHB-EGF) and expressed on the cell surface. The ectodomain shedding of proHB-EGF at the extracellular region on the plasma membrane yields a soluble EGF receptor ligand and a transmembrane-cytoplasmic fragment (HB-EGF-CTF). The cytoplasmic domain of proHB-EGF (HB-EGF-cyto) interacts with transcriptional repressors to reverse their repressive activities. However, how HB-EGF-cyto accesses transcriptional repressors is yet unknown. The present study demonstrates that, after exposure to shedding stimuli, both HB-EGF-CTF and unshed proHB-EGF translocate to the nuclear envelope. Immunoelectron microscopy and digitonin-permeabilized cells showed that HB-EGF-cyto signals are at the inner nuclear membrane. A short sequence element within the HB-EGF-cyto allows a transmembrane protein to localize to the nuclear envelope. The dominant-active form of Rab5 and Rab11 suppressed nuclear envelope targeting. Collectively, these data demonstrate that membrane-anchored HB-EGF is targeted to the inner nuclear membrane via a retrograde membrane trafficking pathway.
A behaviour coordination manager for a mobile manipulator (2004)

In this paper a behaviour coordination manager for a mobile manipulator is proposed. The manager activates and coordinates purposive perception-action units, so-called behaviours, of a mobile manipulator based on a task provided by a deliberative planning system. As a decision making mechanism for the behaviour coordination Bayesian belief networks are applied. The Bayesian belief networks are trained to learn the influence of the behaviours on the manipulators movement in each situation. After development, training, and testing in a virtual environment, the implemented module is transferred to a real mobile manipulator and evaluated there. Finally, experimental results are presented.
Hepatocyte nuclear factor 1A deficiency causes hemolytic anemia in mice by altering erythrocyte sphingolipid homeostasis (2017)

The hepatocyte nuclear factor (HNF) family regulates complex networks of metabolism and organ development. Human mutations in its prototypical member HNF1A cause maturity-onset diabetes of the young (MODY) type 3. In this study, we identified an important role for HNF1A in the preservation of erythrocyte membrane integrity, calcium homeostasis, and osmotic resistance through an as-yet unrecognized link of HNF1A to sphingolipid homeostasis. HNF1A<sup>-/-</sup> mice displayed microcytic hypochromic anemia with reticulocytosis that was partially compensated by avid extramedullary erythropoiesis at all erythroid stages in the spleen thereby excluding erythroid differentiation defects. Morphologically, HNF1A<sup>-/-</sup> erythrocytes resembled acanthocytes and displayed increased phosphatidylserine exposure, high intracellular calcium, and elevated osmotic fragility. Sphingolipidome analysis by mass spectrometry revealed substantial and tissue-specific sphingolipid disturbances in several tissues including erythrocytes with the accumulation of sphingosine as the most prominent common feature. All HNF1A<sup>-/-</sup> erythrocyte defects could be simulated by exposure of wild-type (WT) erythrocytes to sphingosine in vitro and attributed in part to sphingosine-induced suppression of the plasma-membrane Ca<sup>2+</sup>-ATPase activity. Bone marrow transplantation rescued the anemia phenotype in vivo, whereas incubation with HNF1A<sup>-/-</sup> plasma increased the osmotic fragility of WT erythrocytes in vitro. Our data suggest a non-cell-autonomous erythrocyte defect secondary to the sphingolipid changes caused by HNF1A deficiency. Transcriptional analysis revealed 4 important genes involved in sphingolipid metabolism to be deregulated in HNF1A deficiency: <i>Ormdl1</i>, sphingosine kinase-2, neutral ceramidase, and ceramide synthase-5. The considerable erythrocyte defects in murine HNF1A deficiency encourage clinical studies to explore the hematological consequences of HNF1A deficiency in human MODY3 patients.
ChemInform Abstract: Investigations in Indolo[3,2‐b]quinoline Series. (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Long-distance entanglement distribution using individual atoms in optical cavities (2015)

Individual atoms in optical cavities can provide an efficient interface between stationary qubits and flying qubits (photons), which is an essential building block for quantum communication. Furthermore, cavity-assisted controlled-not (cnot) gates can be used for swapping entanglement to long distances in a quantum repeater setup. Nonetheless, dissipation introduced by the cavity during the cnot may increase the experimental difficulty in obtaining long-distance entanglement distribution using these systems. We analyze and compare a number of cavity-based repeater schemes combining various entanglement generation schemes and cavity-assisted cnot gates. We find that a scheme, where high-fidelity entanglement is first generated in a two-photon detection scheme and then swapped to long distances using a recently proposed heralded controlled-$Z$ (cz) gate, exhibits superior performance compared to the other schemes. The heralded gate moves the effect of dissipation from the fidelity to the success probability of the gate thereby enabling high-fidelity entanglement swapping. As a result, high-rate entanglement distribution can be achieved over long distances even for low cooperativities of the atom-cavity systems. This high-fidelity repeater is shown to outperform the other cavity-based schemes by up to two orders of magnitude in the rate for realistic parameters and large distances (1000 km).
Adsorption of CO, intermediately formed in electrochemical reduction of CO2, at a copper electrode (1991)

Electroreduction of CO2 at Cu electrodes in aqueous electrolytes yields CH4 and C2H4, with adsorbed CO formed as an intermediate species. The state of adsorbed CO on a Cu electrode was studied with voltammetric and chronopotentiometric measurements. Adsorbed CO severely restricts hydrogen formation. During cathodic polarisation, coverage by adsorbed CO of the Cu electrode is ca. 90% in CO-saturated electrolytes. The adsorbed CO is easily desorbed by stirring the electrolyte vigorously as revealed by chronopotentiometric measurements. The chronopotentiometric measurements also confirmed that the surface of the copper electrode is fully covered with adsorbed CO during the electro-reduction of CO2, indicating that the rate-determining step for the reduction of CO2 to hydrocarbons must include a reaction which involves the adsorbed CO. The cross-sectional area of adsorbed CO was estimated to be 39 × 10–16 cm2, and the rate of desorption is also discussed using coulometric measurements reported previously.
A Yang Data Model for Transport Slice (2020)

This document provides a YANG data model for the transport slice
service. The model can be used by a client management system of the
transport slice controller to request, configure, and manage the
components of an transport slice service. The YANG modules in this
document conforms to the Network Management Datastore Architecture
(NMDA) defined in RFC 8342.
High-Dose Therapy and Autologous Peripheral Blood Stem Cell Transplantation in Multiple Myeloma: Up-front or Rescue Treatment? Results of a Multicenter Sequential Randomized Clinical Trial (1998)

Results to date indicate that high-dose therapy (HDT) with autologous stem cell support improves survival of patients with symptomatic multiple myeloma (MM). We performed a multicenter, sequential, randomized trial designed to assess the optimal timing of HDT and autotransplantation. Among 202 enrolled patients who were up to 56 years old, 185 were randomly assigned to receive HDT and peripheral blood stem cell (PBSC) autotransplantation (early HDT group, n = 91) or a conventional-dose chemotherapy (CCT) regimen (late HDT group, n = 94). In the late HDT group, HDT and transplantation were performed as rescue treament, in case of primary resistance to CCT or at relapse in responders. PBSC were collected before randomization, after mobilization by chemotherapy, and, in the two groups, HDT was preceded by three or four treatments with vincristine, doxorubicin, and methylprednisolone. Data were analyzed on an intent-to-treat basis using a sequential design. Within a median follow-up of 58 months, estimated median overall survival (OS) was 64.6 months in the early HDT group and 64 months in the late group. Survival curves were not different (P = .92, log-rank test). Median event-free survival (EFS) was 39 months in the early HDT group whereas median time between randomization and CCT failure was 13 months in the late group. Average time without symptoms, treatment, and treatment toxicity (TWiSTT) were 27.8 months (95% confidence interval [CI]; range, 23.8 to 31.8) and 22.3 months (range, 16.0 to 28.6) in the two groups, respectively. HDT with PBSC transplantation obtained a median OS exceeding 5 years in young patients with symptomatic MM, whether performed early, as first-line therapy, or late, as rescue treatment. Early HDT may be preferred because it is associated with a shorter period of chemotherapy.
A Scenario of Service-Oriented Principles Adaptation to the Telecom Providers Service Delivery Platform (2010)

Telecom service providers face a challenge how to increase average revenue per user by new-generation services. In view of the fact that it is extremely difficult to predict the success of the certain kind of service(s), as a result the providers are in need for a dynamic architecture that has to be capable to deliver new services promptly, add resources for successful services as demand increases, or remove unsuccessful services effortlessly. Such architecture has to be a modular standards-based service platform that supports different protocols and interfaces as well as QoS-based transformations and gateways. The potential candidate for this delivery platform is Service Oriented Architecture (SOA). Thus, the aim of our work is to develop a SOA implementation methodology considering telecom service providers existing enterprise network architecture and potential future growth.
Effects of behavioral and pharmacological treatment on smokeless tobacco users. (1996)

The purpose of this study was to examine the effects of 2 mg of nicotine polacrilex versus placebo gum and of group behavioral treatment versus minimal contact on cessation of smokeless tobacco use. Participants (N = 210) were randomly assigned 1 of the 4 treatment conditions. Withdrawal symptoms were assessed throughout the treatment. Follow-up assessments were made at 1, 6, and 12 months posttreatment. Survival curve analysis showed that any of the 3 treatment groups involving group behavioral therapy or placebo gum were equally effective and superior to the minimal contact plus 2 mg of nicotine gum treatment in terms of abstinence. On the other hand, withdrawal symptoms were significantly reduced by nicotine gum, compared with placebo during the initial phases of cessation. The ineffectiveness of nicotine gum on treatment outcome may be attributed to its similarity with smokeless tobacco.
A Review of Current Treatments for Migraine (1994)

Acute drug therapy is the mainstay of treatment for migraine sufferers, with prophylaxis reserved for those with frequent or severe attacks. The majority of treatments have been in use for many years, although their value is often poorly documented due to a lack of well-controlled trials undertaken with defined diagnostic criteria and study end-points. Analgesics with anti-emetics, nonsteroidal anti-inflammatory drugs and ergot derivatives are used for acute treatment. Recently, the selective 5-HT1 receptor agonist sumatriptan has become available and been shown to have significant benefits over traditional therapies for the acute treatment of migraine. Beta-blockers, flunarizine and 5-HT2 antagonists have been used for prophylaxis, and although many patients report a reduction in attack frequency, breakthrough attacks still occur.
The effect of beta-alanine supplementation on neuromuscular fatigue in elderly (55–92 Years): a double-blind randomized study (2008)

We suggest that BA supplementation, by improving intracellular pH control, improves muscle endurance in the elderly. This, we believe, could have importance in the prevention of falls, and the maintenance of health and independent living in elderly men and women.