gebhart/patrepeval huggingface dataset:
Studies of photochemically and electrochemically driven electron transport in zeolites: Progress report, April 1988--April 1989 (1989)

Electron transfer reactions in zeolites and related solid-state materials are being studied. Some particular areas of study are: Electron transfer reactions of linked sensitizer-acceptor molecules. We have studied via laser flash photolysis/transient absorbance the photochemistry of linked Ru(bpy)/sub 3/--diquat molecules exchanged onto the outer surface of zeolite L powder. Electron-donor quenching of excited-state RuL/sub 3/ complexes. We have studied electron transfer reactions between cyanometallate anions M(CN)/sub 8//sup 4/minus// (M = Mo,W), M(CN)/sub 6//sup 4/minus// (M = Fe,Os) and excited state ruthenium complexes; and quantum-size TiO/sub 2/ in zeolite L. We are attempting to prepare systems in which the conduction band of an oxide semiconductor is used to convey electrons from a sensitizer to a catalyst within a zeolite L particle. This report describes progress in the areas of: electron transfer reactions of donor/acceptor molecules at the zeolite/solution interface; and quantum size TiO/sub 2/ supported by zeolites L, Y, and A.
La determinación del resultado en los contratos de larga duración: Principales peculiaridades de la normativa contable francesa y española (2001)

Las caracteristicas de los contratos de larga duracion presentan tal conjunto de peculiaridades diferenciales de los contratos de compra-venta ordinarios que, para las empresas que habitualmente utilizan dichos contratos, suponen una indudable mayor dificultad en la fijacion de cuales, cuando y por cuanto deben de reconocerse los ingresos y gastos imputables a los mismos para la determinacion de sus resultados. En el presente trabajo tratamos de hacer un analisis comparativo de las aportaciones sobre tal cuestion realizadas por el Plan Comptable General (PCG) ?integrado en el AVIS 98-13? y por el AVIS 99-10, emitidos por el Conseil National del Comptabilite (CNC) en Francia, respecto de las realizadas en las Normas de Adaptacion Sectorial del Plan General de Contabilidad a las Empresas Constructoras (NASEC), emitidas por el Instituto de Contabilidad y Auditoria de Cuentas (ICAC) espanol en 1993.
Scintigraphic Detection of Pulmonary Emboli by Serial Positron Imaging of Inhaled15O-Labeled Carbon Dioxide (1978)

Inhaled radioactive carbon dioxide is retained in pulmonary blood distal to embolic obstruction and appears as an area of increased radioactivity that delineates the site and magnitude of the affected zone. The scintigraphic detection of pulmonary emboli by serial imaging of inhaled carbon dioxide labeled with cyclotron-produced 15O2 was evaluated in 27 patients undergoing conventional pulmonary ventilation/perfusion imaging and pulmonary arteriography. Fifteen patients proved to have pulmonary emboli on arteriography. Sensitivity (87%) and specificity (92%) rates for inhalation imaging were superior to those of conventional ventilation/perfusion imaging (P less than 0.05). Clearance of 15O2 activity was markedly delayed over embolized pulmonary segments (mean half time of 47.0 +/- 11.1 seconds [S.E.M.]) in comparison to normal segments (mean of 3.6 +/- 0.08 seconds; P less than 0.001). Pulmonary imaging by this method provides an approach to the detection of pulmonary emboli that is relatively sensitive and specific and permits analysis of persisting perfusion in embolized pulmonary segments. A major practical limitation, however, is the necessity of a nearby cyclotron.
El Monasterio Jerónimo de San Pedro de La Ñora. Aspectos Históricos y Arquitectónicos (2016)

[EN] This thesis deals with the study of one of the latest hieronymite monasteries built, the San Pedro de la Ñora monastery (Murcia, Spain). It is focused on two aspects, knowledge of historical events, some of them unknown until now, from its founding to the secularization and the analysis of its baroque architecture and construction as well as the study of the architects involved in it or that worked for this hieronymite community. And among them, especially Fray Antonio de San Joseph and Fray Pedro de San Agustín, hieronymite monks that were architects involved in its construction and in many others.
Changes in intracellular Ca2+ and pH in response to thapsigargin in human glioblastoma cells and normal astrocytes (2005)

Despite extensive work in the field of glioblastoma research no significant increase in survival rates for this devastating disease has been achieved. It is known that disturbance of intracellular Ca(2+) ([Ca(2+)](i)) and intracellular pH (pH(i)) regulation could be involved in tumor formation. The sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA) is a major regulator of [Ca(2+)](i). We have investigated the effect of inhibition of SERCA by thapsigargin (TG) on [Ca(2+)](i) and pH(i) in human primary glioblastoma multiforme (GBM) cells and GBM cell lines, compared with normal human astrocytes, using the fluorescent indicators fura-2 and BCECF, respectively. Basal [Ca(2+)](i) was higher in SK-MG-1 and U87 MG but not in human primary GBM cells compared with normal astrocytes. However, in tumor cells, TG evoked a much larger and faster [Ca(2+)](i) increase than in normal astrocytes. This increase was prevented in nominally Ca(2+)-free buffer and by 2-APB, an inhibitor of store-operated Ca(2+) channels. In addition, TG-activated Ca(2+) influx, which was sensitive to 2-APB, was higher in all tumor cell lines and primary GBM cells compared with normal astrocytes. The pH(i) was also elevated in tumor cells compared with normal astrocytes. TG caused acidification of both normal and all GBM cells, but in the tumor cells, this acidification was followed by an amiloride- and 5-(N,N-hexamethylene)-amiloride-sensitive recovery, indicating involvement of a Na(+)/H(+) exchanger. In summary, inhibition of SERCA function revealed a significant divergence in intracellular Ca(2+) homeostasis and pH regulation in tumor cells compared with normal human astrocytes.
A comparative feasibility analysis for sensing swelling with textile-based soft strain sensors (2019)

Sensing edema or swelling in the body is a parameter of interest for many clinical and cosmetic applications of wearable technology. Edema creates heightened sensitivity to pressure points, making soft textile-based sensors particularly attractive. However, swelling induces slow, gradual changes in body circumferences, which can be difficult to sense accurately, especially with soft e-textile sensors. Anthropometric variability, sensor placement, and body movements further confound accuracy. Here, we explore the feasibility of accurately sensing ankle swelling through a comparative assessment of a set of sensors representing 3 soft sensing mechanisms in a linear-strain bench test under three frequency conditions. These sensors are then applied in a simulated swelling experiment to assess their performance relative to circumferential changes similar to those experienced in swelling. We find that two sensors (stitched and capacitive) demonstrate reliable performance that approximates or exceeds expert human measurement for swelling. Resistive polymer cord and capacitive sensors exhibited accurate response under medium- and high-frequency extensions.
Correlated frequency hopping-an improved approach to HF spread spectrum communications (2002)

Tactical military operations often drive competing telecommunications requirements. For example, terrain and distances may preclude VHF/UHF line-of-sight communications, yet the HF environment may prove unsatisfactory from too many users in a limited bandwidth or intentional jamming. HF propagation, while favorable for over-the-horizon operations, allows relatively easy communications interception. The Correlated Hopping Enhanced Spread Spectrum (CHESS) waveform is introduced as an improved approach to high-speed, HF digital communications. In general terms, frequency hopping (FH) avoids narrowband interference better than direct sequence (DS) spread spectrum. CHESS improves upon current FH systems with a much shorter frequency dwell, and it does not modulate each hopped pulse. As a result, users sharing the spectrum with CHESS are less likely to experience adjacent or co-channel interference. Moreover, CHESS uses a differential frequency hopping (DFH) technique to encode data, which permits reconstruction of hops missed in the detection process. This error correction is over and above other methods that may be applied. The result is an exceptionally robust, low error rate communications system. Tests have yielded excellent bit error rates at up to 19.2 kbps over short- and long-haul propagation paths. The system uses relatively simple hardware. Essentially, an unmodulated direct digital synthesizer serves as a transmitter, and a fast Fourier transform card detects the signal. Digital signal processing as well as ADC and DAC form the basis of system performance.
Fauna of Protected Areas - 25: Butterflies of Kalakad-Mundanthurai Tiger Reserve, Tamil Nadu (2005)

A survey of Kalakad-Mundanthurai Tiger Reserve (K-MTR), Western Ghats, southern India, from September 2002 to March 2003 revealed the presence of 24 species of butterflies. Observation on diagnostic morphological features, habitat range, larval and adult food, months of abundance, duration of flight, mode of flight and associated habits, mimicry and conservation status are included with meteorological data.
Direct-To-Consumer DNA testing of 6,000 dogs reveals 98.6-kb duplication causing blue eyes and heterochromia in Siberian Huskies (2018)

Summary Consumer genomics enables genetic discovery on an unprecedented scale by linking very large databases of personal genomic data with phenotype information voluntarily submitted via web-based surveys 1 . These databases are having a transformative effect on human genomic research, yielding insights on increasingly complex traits, behaviors, and disease by including many thousands of individuals in genome-wide association studies (GWAS) 2, 3 . The promise of consumer genomic data is not limited to human research, however. Genomic tools for dogs are readily available, with hundreds of causal Mendelian variants already characterized 4–6 , because selection and breeding have led to dramatic phenotypic diversity underlain by a simple genetic structure 7, 8 . Here, we report the results of the first consumer genomics study ever conducted in a non-human model: a GWAS of blue eyes based on more than 3,000 customer dogs with a validation panel of nearly 3,000 more, the largest canine GWAS to date. We discovered a novel association with blue eyes on chromosome 18 ( P = 1x10 -65 ) and used both sequence coverage and microarray probe intensity data to identify the putative causal variant: a 98.6-kb duplication directly upstream of the hox gene ALX4 , which plays an important role in mammalian eye development 9, 10 . This duplication was largely restricted to Siberian Huskies and is highly, but not completely, penetrant. These results underscore the power of consumer-data-driven discovery in nonhuman species, especially dogs, where there is intense owner interest in the personal genomic information of their pets, a high level of engagement with web-based surveys, and an underlying genetic architecture ideal for mapping studies.
Excited-State Absorption Measurements of Sm2+ in CaF2, SrFi2 and SrC12 (1991)

We measured the pump-probe spectrum of the Sm2+ ion in three materials: CaF2, SrP2, and SrCl2. The onset of the observed prominent excited-state absorption band is consistent with an electrostatic model for impurity levels in a solid-state material.
Plasma-Beam-Processed Polyimide Films for the Alignment of Liquid Crystal Molecules (2010)

We demonstrate a plasma-beam-processed polyimide (PI) surface to effectively align liquid crystal (LC) molecules. The pretilt angles of LCs can be varied between 0 and 3.5°, and the PI surface energy can be adjusted by controlling the plasma beam with an energy of 450 eV at an incident angle varying from 0 to 80° with respect to the normal direction of the substrate. Additionally, a method was developed to quickly evaluate the level of anchoring force of LC when compared with a rubbed-aligned LC cell. The performance of this method should be under LC cells with the same alignment materials.
Therapists' Perceptions of Application and Implementation of AM-PAC “6-Clicks” Functional Measures in Acute Care: Qualitative Study (2016)

As participants in this study implemented the AM-PAC "6-Clicks" tools, they considered the role of the measures, how they fit within the context of practice, and their value. They also were concerned with the accuracy and feasibility of the tools. The tools were accepted as potentially valuable to assist administrative decisions and research; however, they were not perceived as particularly useful for routine patient care. Participants lacked complete confidence in the reliability of their scoring and expressed concern that the scores might be substituted for their clinical decision making. They also felt that the tools were too simple to fully reflect patients' overall function and were not useful alone for discharge planning. Participants believed the tools had the potential to be used for communication among colleagues about patients' physical function.
Suppression of power losses during laser pulse propagation in underdense plasma slab (2021)

For current state-of-the-art terawatt lasers, the primary laser scattering mechanisms in plasma include forward Raman scattering (FRS), excitation of plasma waves, and the filamentation instability. Using 2D particle-in-cell (PIC) simulations, we demonstrate that FRS dominates in the regime with medium-to-low density plasma and non-relativistic laser fields. We numerically show that FRS can be suppressed using a two-color laser with frequency detuning exceeding the plasma frequency, Δω&amp;gt;ωpe, leading to a more efficient laser energy transmission. An optimal laser pulse energy redistribution ratio is predicted analytically and verified by PIC simulations.
Crystallization and preliminary X-ray analysis of cardiotoxic phospholipase A2fromOphiophagus hannah(king cobra) (2001)

An acidic phospholipase A2 exhibiting cardiotoxicity, myotoxicity and anti-platelet activity was isolated from Ophiophagus hannah (king cobra) from Guangxi, China. It contains an unusual 'pancreatic loop'. The enzyme was purified to homogeneity and crystallized using polyethylene glycol and ethylene glycol as precipitants. The crystal belongs to space group C2, with unit-cell parameters a = 117.92, b = 62.94, c = 57.16 A, beta = 100.93 degrees. Diffraction data were collected to 2.6 A.
Investigation of Mechanical Properties of Oxide Films Formed on Carbon Steel at High Temperature Corrosive Environments (2004)

The surface degradation of metals that occurs in high temperature corrosive environments has been severe problems of boiler materials in fuel combustion power plant systems. The damage to materials has been often accelerated by mechanical removal of oxide films formed on the material surface. It is therefore very important to investigate mechanical properties and adhesiveness of oxide films at practical high environments, in order to discuss life cycle assessment. Corrosion/oxidation tests were conducted at high temperature corrosive environments of wet air, water steam with hydrogen chloride to look into basic behavior of the corrosion/oxidation. Impact tests were performed on the surface of carbon steel covered with oxide films in the same environments to obtain mechanical properties and adhesiveness of the oxide films. It was found that the corrosive environments increased oxidation of carbon steel a little, and that decreased the fracture strength and other mechanical properties of the oxide films.
Amyloid Fibrils Length Controls Shape and Structure of Nematic and Cholesteric Tactoids (2018)

Amyloid fibrils offer the possibility of controlling their contour length, aspect ratio, and length distribution, without affecting other structural parameters. Here we show that a fine control in the contour length distribution of β-lactoglobulin amyloid fibrils, achieved by mechanical shear stresses of different levels, translates into the organization of tactoids of different shapes and morphologies. While longer fibrils lead to highly elongated nematic tactoids in an isotropic continuous matrix, only sufficiently shortened amyloid fibrils lead to cholesteric droplets. The progressive decrease in amyloid fibrils length leads to a linear decrease of the anchoring strength and homogeneous tactoid → bipolar tactoid → cholesteric droplet transitions. Upon fibrils length increase, we first find experimentally and predict theoretically a decrease of the cholesteric pitch, before full disappearance of the cholesteric phase. The latter is understood to arise from the decrease of the energy barrier separating cholesteric and nematic phases over thermal energy for progressively longer, semiflexible fibrils.
Supplementary Figure 3 from Activation of IL-6R/JAK1/STAT3 Signaling Induces <i>De Novo</i> Resistance to Irreversible EGFR Inhibitors in Non–Small Cell Lung Cancer with T790M Resistance Mutation (2023)

&lt;p&gt;PDF file, 22K, Activation of JAK family by treatment of afatinib.&lt;/p&gt;
Time-Dependent Pathological Changes in Hypoperfusion-Induced Abdominal Aortic Aneurysm (2021)

Hypoperfusion due to vasa vasorum stenosis can cause wall hypoxia and abdominal aortic aneurysm (AAA) development. Even though hypoperfusion is an important contributor toward pathological changes in AAA, the correlation between hypoperfusion and AAA is not fully understood. In this study, a time-dependent semi-quantitative pathological analysis of hypoperfusion-induced aortic wall changes was performed to understand the mechanisms underlying the gradual degradation of the aortic wall leading to AAA formation. AAA-related factors evaluated in this study were grouped according to the timing of dynamic change, and five groups were formed as follows: first group: angiotensin II type 1 receptor, endothelin-1 (ET-1), and malondialdehyde (MDA); second group: matrix metalloproteinase (MMP)-2, -9, -12, M1 macrophages (Mac387+ cells), and monocyte chemotactic protein-1; third group: synthetic smooth muscle cells (SMCs); fourth group: neutrophil elastase, contractile SMCs, and angiotensinogen; and the fifth group: M2 macrophages (CD163+ cells). Hypoxia-inducible factor-1α, ET-1, MDA, and MMP-9 were colocalized with alpha-smooth muscle actin cells in 3 h, suggesting that hypoperfusion-induced hypoxia directly affects the activities of contractile SMCs in the initial stage of AAA. Time-dependent pathological analysis clarified the cascade of AAA-related factors. These findings provide clues for understanding complicated multistage pathologies in AAA.
A Cleavable Propeptide InfluencesToxoplasmaInfection by Facilitating the Trafficking and Secretion of the TgMIC2–M2AP Invasion Complex (2006)

Propeptides regulate protein function and trafficking in many eukaryotic systems and have emerged as important features of regulated secretory proteins in parasites of the phylum Apicomplexa. Regulated protein secretion from micronemes and host cell invasion are inextricably linked and essential processes for the apicomplexan parasite Toxoplasma gondii. TgM2AP is a propeptide-containing microneme protein found in a heterohexameric complex with the microneme protein TgMIC2, a protein that has a demonstrated fundamental role in gliding motility and invasion. TgM2AP function is also central to these processes, because disruption of TgM2AP (m2apKO) results in secretory retention of TgMIC2, leading to reduced TgMIC2 secretion from the micronemes and impaired invasion. Because the TgM2AP propeptide is predicted to be processed in an intracellular site near where TgMIC2 is retained in m2apKO parasites, we hypothesized that the propeptide and its proteolytic removal influence trafficking and secretion of the complex. We found that proTgM2AP traffics through endosomal compartments and that deletion of the propeptide leads to defective trafficking of the complex within or near this site, resulting in aberrant processing and decreased secretion of TgMIC2, impaired invasion, and reduced virulence in vivo, mirroring the phenotypes observed in m2apKO parasites. In contrast, mutation of several cleavage site residues resulted in normal localization, but it affected the stability and secretion of the complex from the micronemes. Therefore, the propeptide and its cleavage site influence distinct aspects of TgMIC2-M2AP function, with both impacting the outcome of infection.
Triazoles. Part XI. Synthesis of 1,2,4-triazole-3-sulphonic acids by oxidation of 1,2,4-triazoline-3-thiones (1970)

1,2,4-Triazoline-3-thiones appear to be practically free from the tautomeric thiols. Oxidation with chlorine or bromine usually affords unstable sulphonyl halides which are readily converted into sulphonamides or, with some exceptions, into sulphonic acids. However, oxidative cleavage of the C–S bond with the formation of 3-unsubstituted or 3-halogenotriazoles occurs with some 2- or 4-substituted 1,2,4-triazoline-3-thiones, especially with bromine as the oxidising agent.
Influence of oxygen insertion on the electrochemistry of chromium(III) dithiocarbamate complexes (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTInfluence of oxygen insertion on the electrochemistry of chromium(III) dithiocarbamate complexesA. M. Bond and G. G. WallaceCite this: Inorg. Chem. 1984, 23, 13, 1858–1865Publication Date (Print):June 1, 1984Publication History Published online1 May 2002Published inissue 1 June 1984https://pubs.acs.org/doi/10.1021/ic00181a016https://doi.org/10.1021/ic00181a016research-articleACS PublicationsRequest reuse permissionsArticle Views89Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts