gebhart/patrepeval huggingface dataset:
Predicting Depressive Symptom Severity through Individuals' Nearby Bluetooth Devices Count Data Collected by Mobile Phones: A Preliminary Longitudinal Study (2021)

The Bluetooth sensor embedded in mobile phones provides an unobtrusive, continuous, and cost-efficient means to capture individuals' proximity information, such as the nearby Bluetooth devices count (NBDC). The continuous NBDC data can partially reflect individuals' behaviors and status, such as social connections and interactions, working status, mobility, and social isolation and loneliness, which were found to be significantly associated with depression by previous survey-based studies. This paper aims to explore the NBDC data's value in predicting depressive symptom severity as measured via the 8-item Patient Health Questionnaire (PHQ-8). The data used in this paper included 2,886 bi-weekly PHQ-8 records collected from 316 participants recruited from three study sites in the Netherlands, Spain, and the UK as part of the EU RADAR-CNS study. From the NBDC data two weeks prior to each PHQ-8 score, we extracted 49 Bluetooth features, including statistical features and nonlinear features for measuring periodicity and regularity of individuals' life rhythms. Linear mixed-effect models were used to explore associations between Bluetooth features and the PHQ-8 score. We then applied hierarchical Bayesian linear regression models to predict the PHQ-8 score from the extracted Bluetooth features. A number of significant associations were found between Bluetooth features and depressive symptom severity. Compared with commonly used machine learning models, the proposed hierarchical Bayesian linear regression model achieved the best prediction metrics, R2= 0.526, and root mean squared error (RMSE) of 3.891. Bluetooth features can explain an extra 18.8% of the variance in the PHQ-8 score relative to the baseline model without Bluetooth features (R2=0.338, RMSE = 4.547).
Second-Harmonic Generation in Plane-Piston Beams (1970)

A perturbation method is used to calculate the second harmonic (“H2”) that is generated by nonlinear processes in the first-harmonic (“H1”) beam from a circular plane-piston source of radius a, in a rigid baffle, radiating at wavelength λ into an essentially dissipationless fluid. Williams et. al [J. Acoust. Soc. Amer. 37, 1181(A) (1965)] calculated H2 along the beam axis, z. We have evaluated H2 off-axis (0⩽r⩽a) for the fairly near field, with approximations valid when a/λ ≈ 10–40. For a/λ ≈ 18, at axial distances 5a≲z≲15a, predictions agree well with measurements [Gould et al., J. Acoust. Soc. Amer. 40, 421–427 (1966)]. As a/λ → ∞, H1 approaches a cylindrically collimated beam of plane waves with constant amplitude, all “structure” being within an infinitesimal paraxial region; H2 approaches cylindrically collimated plane waves with amplitude proportional to z. Although both results are often assumed in practice, neither holds accurately below frequencies so high that absorption must be overwhelming. [Supported in part by U. S. Office of Naval Research.]
The Relationship of Internalized Weight Bias to Weight Change in Treatment-Seeking Adults with Overweight (2022)

The present study examined data from a randomized controlled trial exploring whether behavioral weight loss treatment was associated with changes in internalized weight bias. The relationship between internalized weight bias and psychological functioning was also assessed. Participants were 106 men and women with overweight or obesity enrolled in a treatment outcome study using the Lifestyle Balance Program. Participants completed measures of internalized weight bias, anti-fat attitudes, self-esteem, body image concern, depressive symptoms, anxiety, and stress. Variables were assessed at baseline, post-treatment, and six-month follow-up. Weight bias internalization significantly decreased over the course of treatment. Baseline and follow-up internalized weight bias scores predicted change in body weight. Participants reporting the lowest levels of internalized weight bias at baseline lost nearly twice as much weight as participants reporting the highest levels of internalized weight bias. Significant associations were found between internalized weight bias, body image concern, and self-esteem. Findings indicate a relationship between internalized weight bias and weight change during behavioral weight loss treatment, highlighting the importance of assessing baseline levels of internalized weight bias in weight loss treatment studies. Higher internalized weight bias predicted poorer weight loss outcomes, indicating a need for tailored treatment approaches.
Shoe contact dermatitis (1980)

The incidence of contact allergy was studied in a series of 165 patients with eczematous dermatitis of the feet correlated clinically with shoe contact. Positive reactions to one or more substances were recorded in 108 patients (65.4%). Among the relevant sensitizers were chromium, paraphenylenediamine, paratertiary butylphenolformaldehyde resin and nickel, while the other allergens were benzocaine, neomycin, balsam of Peru, ethylenediamine and parabens. Allergic contact dermatitis of the feet can be prevented by recognition of the allergens responsible, control of hyperhidrosis and avoidance of topical allergens.
An unusual shadow above the aortic valve (2016)

What is the most likely diagnosis? Acute type A aortic dissectionWilliams syndromeLoa loa worm infectionIntimo-intimal intussusceptionGiant cell aortitis.
Culturing Periprosthetic Tissues in BacT/Alert® Virtuo Blood Culture Bottles for a Short Duration of Post-operative Empirical Antibiotic Therapy (2020)

<b>Introduction:</b> A post-operative empirical antibiotic therapy (PEAT) is required in periprosthetic joint infections. It commonly uses broad-spectrum antibiotics to cover most Gram-positive cocci and Gram-negative bacilli. It is currently continued until first microbiological results are available, no less than five days later. <b>Methods:</b> We performed a retrospective study in order to evaluate duration of incubation required for surgical samples using the BacT/Alert® Virtuo blood culture bottles system. <b>Results:</b> Among 216 surgical interventions and 199 clinical strains (53.8% staphylococci, 22,1% streptococci and enterococci, 14,6% Gram-negative bacilli, 5,5% anaerobes), 90.5% of the strains were detected between day 0 and day 2; 15 infective strains are cultured from day 3 including 8 <i>Cutibacterium</i> sp., 4 staphylococci, 2 streptococci and 1 <i>Enterococcus</i>. <b>Conclusions:</b> We suggest that the duration of PEAT in patients operated for a periprosthetic joint infection may be shortened to three days as Gram-negative rods are unlikely to grow after three days of culture by using BacT/Alert® Virtuo blood culture bottles. This is likely to shorten the overall length of hospital stay, to diminish the occurrence of adverse side effects, and the emergence of antimicrobial resistance. However, coverage of Gram-positive cocci should be maintained for 14 days until the definite culture results are available.
Cell-mediated and humoral immune responses in broiler chickens maintained on diets containing different levels of vitamin A (1997)

Broiler chickens were examined for the effects of low (400 IU/kg), standard (1,500 IU/kg), or high (15,000 IU/kg) dietary vitamin A (VitA) levels on immune responsiveness postimmunization to Newcastle disease virus (NDV). A control pair-fed group (1,500 IU/kg) was included to compensate for the reduced feed intake associated with diet containing the low level of VitA. Interdigital skin reactions to phytohemagglutinin (PHA) and CD4:CD8 T lymphocyte ratios were significantly reduced in chickens fed the low VitA diet, whereas their antibody responses to NDV were significantly increased as compared to birds that consumed the 1,500 to 15,000 VitA diet ad libitum. On the other hand, birds on the high VitA diet had reduced lymphocyte responses to concanavalin A and pokeweed, but not to PHA. No effect of dietary VitA was observed for natural killer activity, nor on levels of percentage of cells expressing Class II MHC antigens among groups that consumed feed ad libitum. The results indicated that both humoral and cellular immune responses were modulated by levels of VitA in the diet, and suggest that VitA-deficient chickens developed a T helper (Th)2 immune response, whereas the chickens fed highly enriched VitA diet showed a Th1 immune response.
Multisignatures secure under the discrete logarithm assumption and a generalized forking lemma (2008)

Multisignatures allow n signers to produce a short joint signature on a single message. Multisignatures were achieved in the plain model with a non-interactive protocol in groups with bilinear maps, by Boneh et al, and by a three-round protocol under the Discrete Logarithm (DL) assumption, by Bellare and Neven, with multisignature verification cost of, respectively, O(n) pairings or exponentiations. In addition, multisignatures with O(1) verification were shown in so-called Key Verification (KV) model, where each public key is accompanied by a short proof of well-formedness, again either with a non-interactive protocol using bilinear maps, by Ristenpart and Yilek, or with a three-round protocol under the Diffie-Hellman assumption, by Bagherzandi and Jarecki.
How Execution of Strategy Prevented Indian Bank in DIFC to Fight Effects of COVID 2019 (2021)

The purpose of this paper is to find out the effects of covid19 pandemic on Indian banks functioning in the Dubai International Financial Center (DIFC) additionally, also how banks are combatting the negative impacts on the business therefore, finding the strategies and tactics of the banks. The design used to receive data was primarily questionnaires and analyzing them using various statistics tools. The aftermath of analysis, banks have made sure that there is minimum burden on their customers. Furthermore banks have also provided various health safety guidelines to protect their employees, banks have had various negative impacts too for example the number of NPA's has increased, slowdown in operation of business. The conclusion would be that the pandemic has ruptured the financial institutions, but the banks are trying to prevent the business from heading into a major loss as banks also have alternative income like investing in corporate and sovereign bonds.
[Utility of Presurgical Evaluation Using Stereoelectroencephalography(SEEG)]. (2022)

Precise localization of the "epileptogenic zone(EZ)" is the goal of presurgical investigations in patients with drug-resistant focal epilepsy. Intracranial electroencephalography recordings are required when noninvasive evaluation results are not consistent. Although subdural grid electrodes(SDG)have been widely used in Japan, stereoelectroencephalography(SEEG)has been recently introduced. The principle of SEEG is based on anatomo-electro-clinical correlations to investigate surgical hypotheses that are primarily driven by the analysis of seizure semiology as well as other noninvasive investigations. The most important element of the SEEG methodology is to formulate preimplantation electrode trajectories considering the anatomo-electro-clinical correlations of epileptic seizures. If the preimplantation hypotheses are insufficient or incorrect, SEEG recordings will not identify the EZ. A detailed analysis of seizure semiology with respect to anatomo-electro-clinical correlates, particularly including various deep structures, such as the insular, operculum, and cingulate cortex, forms the basis of the implantation strategy for SEEG. The strategy of implantation is not to map the lobes/lobules but the epileptic networks, which usually involve multiple lobes, indicating that the theory of SEEG is completely different from that of SDG. Herein, we introduce the basics of SEEG, especially presurgical evaluations, with a representative case presentation.
Estimation of nonlinear refractive index in various silica-based glasses for optical fibers (1995)

The dependence of the nonlinear refractive index n2 on glass compositions for optical fibers is clarified. The relation between n2 and germanium- or fluorine-doped SiO2 is calculated on the basis of the measurement of n2 at 1.55 μm with the improved cross-phase-modulation method, taking into account the radial distribution of the optical power in the fibers.
Cerebral blood flow is associated with matrix metalloproteinase levels during the early symptomatic phase of concussion (2021)

Concussion is associated with disrupted cerebral blood flow (CBF), although there appears to be substantial inter-individual variability in CBF response. At present, the mechanisms of variable CBF response remain incompletely understood, but one potential contributor is matrix metalloproteinase (MMP) expression. In more severe forms of acquired brain injury, MMP up-regulation contributes to CBF impairments via increased blood-brain barrier permeability. A similar relationship is hypothesized for concussion, where recently concussed individuals with higher MMP levels have lower CBF. To test this hypothesis, 35 concussed athletes were assessed longitudinally at early symptomatic injury (median: 5 days post-injury) and at medical clearance (median: 24 days post-injury), along with 71 athletic controls. For all athletes, plasma MMPs were measured and arterial spin labelling was used to measure CBF. Consistent with our hypothesis, higher concentrations of MMP-2 and MMP-3 were correlated with lower global CBF. The correlations between MMPs and global CBF were also significantly diminished for concussed athletes at medical clearance and for athletic controls. These results indicate an inverse relationship between plasma MMP levels and CBF that is specific to the symptomatic phase of concussion. Analyses of regional CBF further showed that correlations with MMP levels exhibited some spatial specificity, with greatest effects in occipital, parietal and temporal lobes. These findings provide new insights into the mechanisms of post-concussion cerebrovascular dysfunction.
A Similarity-Based Classification Framework for Multiple-Instance Learning (2014)

Multiple-instance learning (MIL) is a generalization of supervised learning that attempts to learn useful information from bags of instances. In MIL, the true labels of instances in positive bags are not available for training. This leads to a critical challenge, namely, handling the instances of which the labels are ambiguous (ambiguous instances). To deal with these ambiguous instances, we propose a novel MIL approach, called similarity-based multiple-instance learning (SMILE). Instead of eliminating a number of ambiguous instances in positive bags from training the classifier, as done in some previous MIL works, SMILE explicitly deals with the ambiguous instances by considering their similarity to the positive class and the negative class. Specifically, a subset of instances is selected from positive bags as the positive candidates and the remaining ambiguous instances are associated with two similarity weights, representing the similarity to the positive class and the negative class, respectively. The ambiguous instances, together with their similarity weights, are thereafter incorporated into the learning phase to build an extended SVM-based predictive classifier. A heuristic framework is employed to update the positive candidates and the similarity weights for refining the classification boundary. Experiments on real-world datasets show that SMILE demonstrates highly competitive classification accuracy and shows less sensitivity to labeling noise than the existing MIL methods.
Designing roadmaps for the Galileo Commercial Service platform (2012)

Unlike existing Global Navigation Satellite Systems, future Galileo is envisioned to provide a Commercial Service (CS) with improved as well as new characteristics. However, as yet, it is still highly unclear whether Location Based Service (LBS) providers are in fact interested to pay for accessing CS signals. The purpose of this paper is two-fold: First, to show how business model roadmapping can be used for analyzing the impact of a new service offering on customer and second, to demonstrate the steps and activities that have to be done in order to create a business model for Galileo CS. The roadmap-based study identified three crucial points that the European Commission and the future Galileo operating company should take into account in their planning for the future: First, the creation of awareness on Galileo CS platform at an early stage, second, getting LBS providers on board by applying progressive pricing schemes or choosing non-discriminatory pricing schemes and third, getting governments on board to create trust and reputation for the platform or focusing attention on LBS providers directly.
Mapping the lineage relationship between CXCR5 + and CXCR5 - CD4 + T cells in HIV infected human lymph nodes (2019)

Summary CXCR5 is a key surface marker expressed on follicular helper T (T FH ) cells. We report here B cell help functionality in a population of CD4 + T cells isolated from primary human lymph nodes (LN) that lacked CXCR5 expression. This CXCR5 - subset is distinguished from other CXCR5 - CD4 + T cells by high PD-1 expression. Accumulation of CXCR5 - PD-1 + T cells correlated with peripheral CD4 + T cell depletion and an increase in T-bet + B cells in the LN, highlighting these atypical CD4 + T cells as a key component of lymphoid dysregulation during chronic HIV infection. By interrogating the phenotypic heterogeneity, functional capacity, TCR repertoire, transcriptional profile, and epigenetic state of CXCR5 - PD-1 + T cells, we showed that CXCR5 - PD-1 + T cells are related to CXCR5 + PD-1 + T cells and provided evidence for the down regulation of CXCR5 following cell division as one mechanism for the absence of CXCR5 expression. Notably, CXCR5 - PD-1 + T cells exhibited a migratory transcriptional program and contributed to circulating CXCR5 - PD-1 + T cells with B cell help functionality in the peripheral blood. Thus, these data link LN pathology to circulating T cells and expand the current understanding on T cell diversity in the regulation of B cell responses during chronic inflammation. High dimensional profiling of activated CD4 + T cells in HIV infected lymph nodes revealed an accumulation of a CXCR5 negative subset. CXCR5 - PD-1 + CD4 + T cells exhibited T FH -like protein expression and function. CXCR5 - PD-1 + CD4 + T cells are related to T FH cells by clonal lineage and epigenetic similarity. CXCR5 - PD-1 + CD4 + T cells upregulate a migratory gene program and contribute to circulating T cells with B cell help functionality
A thin shell volume for modeling human hair (2002)

Hair-to-hair interaction is often ignored in human hair modeling, due to its computational and algorithmic complexity. In this paper, we present our experimental approach to simulate the complex behavior of long human hair, taking into account the hair-to-hair interactions. For long hair, we propose the thin shell volume (TSV) model for enhancing hair realism by simulating complex hair-hair interaction. The TSV is a thin bounding volume that encloses a given hair surface. The TSV method enables virtual hair combing for surface-model hairstyles. Combing produces the effects of hair-hair interaction that occur in real human hair. Any hair model based on a surface representation can benefit from this approach. The TSV is presented mainly as a tool to modeling human hair, but this model also gives rise to global hair animation control.
Association of HLA-DQ Heterodimer Residues −18β and β57 With Progression From Islet Autoimmunity to Diabetes in the Diabetes Prevention Trial–Type 1 (2022)

HLA-DQ structural motifs appear to modulate progression from islet autoimmunity to diabetes among at-risk relatives with islet autoantibodies. Residue -18β within the signal peptide may be related to levels of protein synthesis and β57 to stability of the peptide-DQab trimolecular complex.
Impact of Regular Physical Activity on Aortic Diameter Progression in Paediatric Patients with Bicuspid Aortic Valve (2021)

Patients with bicuspid aortic valve (BAV) have an increased risk of aortic dilation and aortic dissection or rupture. The impact of physical training on the natural course of aortopathy in BAV patients remains unclear. The aim of this study was to evaluate the impact of regular physical activity on aortic diameters in a consecutive cohort of paediatric patients with BAV. Consecutive paediatric BAV patients were evaluated and categorized into two groups: physically active and sedentary subjects. Only the subjects with a complete 2-year follow-up were included in the study. To evaluate the potential impact of physical activity on aortic size, aortic diameters were measured at the sinus of Valsalva and mid-ascending aorta using echocardiography. We defined aortic diameter progression the increase of aortic diameter ≥ 10% from baseline. Among 90 BAV patients (11.5 ± 3.4 years of age, 77% males), 53 (59%) were physically active subjects. Compared to sedentary, physically active subjects were not significantly more likely to have > 10% increase in sinus of Valsalva (13% vs. 8%, p-value = 0.45) or mid-ascending aorta diameter (9% vs. 13%, p-value = 0.55) at 2 years follow-up, both in subjects with sinus of Valsalva diameter progression (3.7 ± 1.0 mm vs. 3.5 ± 0.8 mm, p-value = 0.67) and in those with ascending aorta diameter progression (3.0 ± 0.8 mm vs. 3.2 ± 1.3 mm, p-value = 0.83). In our paediatric cohort of BAV patients, the prevalence and the degree of aortic diameter progression was not significantly different between physically active and sedentary subjects, suggesting that aortic dilation is unrelated to regular physical activity over a 2-year period.
Contact dermatitis to fragrances (1987)

2 groups of patients (1200 and 1500 respectively) were patch tested with different concentrations of perfume mix and fragrance raw materials. The study was to evaluate the incidence of contact dermatitis to fragrances in Roma, Italy, and the influence of limited variations in fragrance and perfume mix concentrations on patch test responses. The results showed that a decrease in the perfume mix concentration from 16% to 8% correlated with a decrease in the % of positive patients (from 5.2% to 3.6%). Variations in the concentration of fragrance raw materials did not influence the % of positive reactions in the 2 groups. The perfume mixture at 16% or 8% gave some positive results, without a corresponding reaction to any of the constituents, that were not related to an excited skin syndrome.
High-level mobility skills in children and adolescents with traumatic brain injury (2015)

The HiMAT is a reliable, valid and sensitive measure of high-level mobility skills following childhood TBI. The high-level mobility skills of children with TBI are less proficient than their peers.
Development of DNA aptamers targeting low-molecular-weight amyloid-β peptide aggregatesin vitro (2018)

We have developed a novel functional nucleic acid aptamer to amyloid-β peptide 1-40 (Aβ1-40) and investigated its potential to detect Aβ peptide fragments in neuropathologically confirmed Alzheimer brain hippocampus tissues samples. Our results demonstrate that the aptamer candidate RNV95 could detect tetrameric/pentameric low-molecular-weight Aβ aggregates in autopsy hippocampal tissue from two neuropathologically confirmed Alzheimer disease cases. Although these are preliminary observations, detailed investigations are under way. This is the first demonstration of aptamer-Aβ binding in Alzheimer brain tissues.