gebhart/patrepeval huggingface dataset:
Non respiratory metabolic function and morphology of lung following exposure to polybrominated biphenyls in rats (1982)

Exposure to polybrominated biphenyls (PBBs) resulted in increased activity of microsomal arylhydrocarbon hydroxylase and ethoxyresorufin-O-deethylase in rat lung. Clearance of 5-hydroxytryptamine (5-HT) and angiotensin 1 by perfused lungs was decreased by PBBs. However, PBBs had no effect on the activity of epoxide hydrolase, monoamine oxidase, or angiotensin-converting enzyme in lung. The only histopathologic change detected in lungs from PBB-treated rats was an increase in alveolar type II cell lamellar bodies. Selective accumulation of certain PBB congeners by lung was not observed in this investigation.
Pervasive healthcare 2010: two perspectives (2011)

The second Pervasive Health column presents a retrospective of the most recent International Conference on Pervasive Computing Technologies for Healthcare (Pervasive Healthcare). The descriptions come from two perspectives: one from the technical program chair and one from an attendee and presenter.
Évaluation d'une Méthode de Synthèse Spectrale 2D+T pour la Transparence de Parois sous Champ Acoustique Diffus (2016)

National audience
Frontispiece: Unconventional Route to Oxygen‐Vacancy‐Enabled Highly Efficient Electron Extraction and Transport in Perovskite Solar Cells (2020)

Electron Transport An acid-treatment strategy was used to create an amorphous TiO2 buffer layer situated on the anatase TiO2 surface as an efficient electron-transport layer, as described by Z. Lin, Z. L. Wang, Y. Yang, and co-workers in their Research Article on page 1611.
Progress in developing nanophotonic fabrication (2009)

For future optical transmission systems with high data transmission rates and capacity, we have proposed nanometer-scale photonic devices (i.e., nanophotonics devices). These devices consist of nanometer-scale dots, and an optical near-field is used as the signal carrier.
The intra and inter-subject reproducibility of rodent olfactory bulb activity maps measured with fMRI (2005)

The first processing center in the mammalian olfactory system is the olfactory bulb (OB), a structure in which 2000 neuropil spheroids called glomeruli encode the input from 1000 types of olfactory receptor neurons, each specific for a particular chemical feature. Many imaging modalities have been used to simultaneously assess the activity of many of these channels and have provided insight into the way in which volatile odorants are represented in the OB. However, there has been little evaluation of the functional differences between animals or the extent to which given animal's response is conserved over multiple trials. Here we have used high-resolution fMRI to quantitatively evaluate the similarity of patterns produced by the same subject to a repeated stimulus and to compare the responses of different subjects to the same stimulus. Male Sprague-Dawley rats under urethane anesthesia were stimulated with iso-amyl acetate or carvone (-) in this study. All data were acquired on a modified 7 T Bruker Biospec. Imaging experiments were performed using fast low-angle single-shot (FLASH) gradient-echo sequence. T1-weighted FLASH anatomical images have resolution of 110110250 m3. Each fMRI experiment contained a series of 24 T2*-weighted FLASH images (resolution = 220220250 m3). The mean image of the pre-stimulation baseline images was subtracted from the stimulation images on a pixel-by-pixel basis to generate student t-maps, which were overlaid onto the corresponding anatomical images to locate the activated region in the OB. Activity maps of the entire glomerular layer were constructed with an algorithm that integrates the glomerular data from multiple slices. OB activity maps from the same subject were highly conserved from trial to trial using the odorant carvone (-) at the same concentration and exposure duration. A quantitative comparison of the fraction of pixels activated by both trials for multiple odorants yielded values from 48 to 60%. In contrast, there was more substantial variability when a given odorant was tested in multiple subjects. Figure 1 shows the response of multiple animals to an equivalent exposure of iso-amyl acetate. While there is considerable variability in the fraction of the OB involved and the intensity of that involvement (1a), when the images are equivalently scaled and averaged it becomes clear that there are certain shared regions of activity (1b). This is consistent with genetic studies in which olfactory receptor neuron projections vary greatly between individuals but still localize to broadly defined regions. In conclusion, the consistency of intra-subject patterns and the variability of inter-subject patterns suggest that the primary causes for variations in the responses to identical stimuli are neuroanatomical. These findings help to validate the use of fMRI in the study of olfaction and recommend caution in comparing patterns from different animals.
Ion-pair evaporation from ionic liquid clusters (2010)

A differential mobility analyzer (DMA) is used in atmospheric pressure N(2) to select a narrow range of electrical mobilities from a complex mix of cluster ions of composition (CA)(n)(C(+))(z). The clusters are introduced into the N(2) gas by electrospraying concentrated (approximately 20 mM) acetonitrile solutions of ionic liquids (molten salts) of composition CA (C(+) = cation, A(-) = anion). Mass analysis of these mobility-selected ions reveals the occurrence of individual neutral ion-pair evaporation events from the smallest singly charged clusters: (CA)(n)C(+)-->(CA)(n-1)C(+)+CA. Although bulk ionic liquids are effectively involatile at room temperature, up to six sequential evaporation events are observed. Because this requires far more internal energy than available in the original clusters, substantial heating (approximately 10 eV) must take place in the ion guides leading to the mass analyzer. The observed increase in IL evaporation rate with decreasing size is drastic, in qualitative agreement with the exponential vapor pressure dependence predicted by Kelvin's formula. A single evaporation event is barely detectable at n = 13, while two or more are prominent for n < or = 9. Magic number clusters (CA)(4)C(+) with singularly low volatilities are found in three of the four ionic liquids studied. Like their recently reported liquid phase prenucleation cluster analogs, these magic number clusters could play a key role as gas-phase nucleation seeds. All the singularly involatile clusters seen are cations, which may help understand commonly observed sign effects in ion-induced nucleation. No other charge-sign asymmetry is seen on cluster evaporation.
Noninvasive Tests for Liver Fibrosis (2006)

The field of noninvasive markers for the assessment of hepatic fibrosis has seen tremendous growth in the last two decades. Surrogate markers are gradually being substituted for biomarkers that reflect the complex balance between synthesis and degradation of the extracellular matrix. Coupled with these promising tests are artificial intelligence networks devised by sophisticated statistical instruments that incorporate a battery of laboratory tests and biomarkers with imaging modalities. Recently, gene identification and protein analysis have shown promise in identifying selected patients with mild or advanced fibrosis. Despite such progress, an important limitation of these tests is the frequent inability to detect mild fibrosis although patients at the end of the histological spectrum (i.e., advanced fibrosis or cirrhosis) are readily identified. With time, it is anticipated a combination of serological and radiological tests together with genetic and proteomic investigations will provide accurate assessment of fibrosis in a cost-effective and timely manner.
Silicon-Nitride-Assisted Edge Coupler Interfacing With High Numerical Aperture Fiber (2019)

Reducing the mode size mismatch between highindex-contrast silicon waveguide and single-mode fiber takes an important role in photonic integration. A low-loss and broadband silicon-nitride-assisted edge coupler for the coupling of light between silicon wire waveguides and high numerical aperture fiber is proposed and optimized for TE polarization. The mode size converter is composed of silicon inverse taper waveguides in the core and two silicon nitride interlayers spaced by silica in cladding layers. The edge coupler is characterized by cleaved high numerical aperture fiber (mode field diameter is about 6.5 μm). With the help of refractive index matching oil (n = 1.46), the coupling loss for TE polarized light input is 0.35 dB at 1570 nm. The 1-dB bandwidth is 95 nm. The 1-dB alignment tolerances are higher than ± 2.5 and ± 1 μm in the horizontal and vertical directions, respectively, and higher than 25 μm in the axial direction.
An Electro-Optical Simulation Methodology for the Analysis of Single-Event Radiation Effects in Photonic Devices (2019)

A multiphysics simulation methodology is presented for the analysis of transient radiation effects in photonic integrated devices and circuits. Electrical and optical simulators are coupled by computing steady-state optical solutions at various time intervals during transient charge transport simulations. This approach allows for the simulation of transient effects, enabling new studies of radiation effects in photonic integrated circuits (PICs), currently limited to analysis of single optical devices. This methodology will also allow for the development of compact models for lumped parameter simulation of radiation effects at the circuit and system levels, which will aid the design and analysis of PICs for operation in space or other harsh radiation environments.
Regulation of gene expression in developing epidermal epithelia (1997)

Skin is one of the most thoroughly studied epithelia and can be used as a model for transcriptional control of epithelial differentiation. In particular, the stages of epidermal development and differentiation from a simple epithelium are well characterized. Temporal gene expression during development can be used to assign roles for transcription factors in epidermal differentiation. Approaches to understanding transcriptional regulation in epidermis include extensive promoter analysis and expression studies, in some cases coupled to functional studies. This work has not produced any consensus about the importance of any particular factor or class of factors in epidermal specification. There is, as yet, nothing similar to the myo D family of tissue-specific and cell-type determining factors in epidermis. These studies, however, have revealed much about control of the differentiation process in epidermis. Most recently, there has been a suggestion that epithelial transcription can be influenced directly by the status of the adhesion complexes at the cell surface, providing a direct link between one of the distinguishing features of the epithelial state and gene transcription.
Influence of alcohol addition on the .gamma.-CD:pyrene complex (1991)

The interaction of γ-cyclodextrin (CD) with pyrene in the presence of different linear, branched, and cyclic alcohols is reported. In the presence of γ-CD, the fluorescence emission spectra of pyrene showed only the monomer emission. The 1:1 stoichiometry between γ-CD and pyrene has been confirmed in the presence of the alcohols examined. Apparent formation constants were calculated by using the variation in the I/III vibronic band ratio of pyrene and nonlinear regression analysis. The apparent formation constants increased dramatically in the presence of the alcohols. Of all the alcohols examined, cyclohexanol produced the largest enhancement in the apparent formation constant (a 37-fold increase). The present work suggests that the role of the alcohol in the γ-CD:pyrene complex is somewhat different than recently reported for the β-CD:pyrene complex. © 1991 American Chemical Society.
White and Gray Matter Abnormalities in Manifest Huntington's Disease: Cross‐Sectional and Longitudinal Analysis (2020)

This study showed broad GM and WM abnormalities in manifest HD patients. Reductions in FA and cortical thinning correlated significantly with the disturbances of motor and cognitive processing that describe HD. Follow-up assessment showed that the CC is compromised in the absence of detectable GM changes or motor decline, suggesting it plays an important role in disease progression.
Multimodal Generally Recognized as Safe ZnO/Nanocopper Composite: A Novel Antimicrobial Material for the Management of Citrus Phytopathogens (2017)

Copper (Cu) bactericides/fungicides are used extensively for crop protection in agriculture. Concerns for Cu accumulation in soil, Cu leaching into the surrounding ecosystem, and development of Cu resistance in phytopathogenic bacteria are evident. While there is no suitable alternative to Cu available to date for agricultural uses, it is possible to reduce Cu per application by supplementing with Zn and improving Cu bioavailability using nanotechnology. We have prepared a non-phytotoxic composite material consisting of generally recognized as safe ZnO 800 particles and nanocopper-loaded silica gel (ZnO-nCuSi). The morphology of the ZnO-nCuSi material was characterized using scanning electron microscopy, showing ZnO particles dispersed in the silica gel matrix. ZnO-nCuSi demonstrated strong in vitro antimicrobial properties against several model plant bacterial species. Two consecutive year field efficacy results showed that agri-grade ZnO-nCuSi was effective in controlling citrus canker disease at less than half the metallic rate of the commercial cuprous oxide/zinc oxide pesticide.
New List Decoding Algorithms for Reed–Solomon and BCH Codes (2008)

In this paper, we devise a rational curve fitting algorithm and apply it to the list decoding of Reed-Solomon and Bose-Chaudhuri-Hocquenghen (BCH) codes. The resulting list decoding algorithms exhibit the following significant properties.
A natural PPAR- agonist, 15-deoxy-delta 12,14-prostaglandin J2, may act as an enhancer of PAI-1 in human proximal renal tubular cells under hypoxic and inflammatory conditions (2008)

The endogenous PPAR-gamma agonist, 15d-PGJ2, increased PAI-1 expression independently of PPAR-gamma via the activation of TK or MAP kinase in HPTECs and may act as an enhancer of PAI-1 production in the kidney under hypoxic and inflammatory conditions.
Retinoids and EZH2 inhibitors cooperate to orchestrate cytotoxic effects on bladder cancer cells (2023)

ABSTRACT Emerging evidence has highlighted the importance of targeting EZH2 in bladder cancer owing to the highly mutated nature of bladder cancers harboring mutations in chromatin regulatory genes opposing Polycomb-mediated repression. Besides, enhanced expression of EZH2 contributes to pathogenesis. Furthermore, the critical role of the retinoic acid signaling pathway in the development and homeostasis of the urothelium is well established. Here we report that coordinated targeting of EZH2 and the retinoic acid signaling pathway caused cytotoxic effects on bladder cancer cells by inducing a synergistic reduction in proliferative potential that was associated with increased apoptosis and cell cycle arrest in a cooperative and orchestrated manner. Moreover, combined treatment caused the modulation of the expression of genes associated with an anti-oncogenic profile, as reflected by the stimulation of marker genes associated with apoptosis and differentiation. We further portrayed a molecular mechanism whereby EZH2 maintains H3K27me3-mediated repression of certain genes associated with unfolded protein response and some metabolic processes. This work also characterized an apoptotic program centered on the master transcriptional regulators C/EBPβ and CHOP. These findings highlight the importance of co-targeting the EZH2/retinoic acid pathway in bladder cancers and encourage the design of novel treatments employing retinoids coupled with EZH2 inhibitors in bladder carcinoma.
In Vitro Cytotoxicity of Imidazolyl-1,3,5-triazine Derivatives. (1997)

We examined in vitro cytotoxic activity of imidazolyl-1,3,5-triazine derivatives using human breast cancer cell lines (MCF-7, R-27, T-47D and ZR-75-1) and murine leukemia cell line (P388). The percentage of viable cells was determined by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazorium bromide (MTT) assay. Hexamethylmelamine (HMM), a 1,3,5-triazine derivative has previously been recognized as an antitumor agent effective against lung, ovarian and breast cancer, but failed to show a significant cytotoxic activity in the present study. In contrast, four imidazolyl-1,3,5-triazine derivatives, 2-(1-imidazolyl)-4,6-bis(morpholino)-1,3,5-triazine, 2-(1-imidazolyl)-4-morpholino-6-(3-thiazolidinyl)-1,3,5-triazine, 2-(4-cyano-4-phenylpiperidino)-4-(1-imidazolyl)-6-morpholino-1,3,5-triaz ine and 2-(1-imidazolyl)-4-(N-methyl-N-phenylamino)-6-morpholino-1,3,5-triazine showed cytotoxic activity for most cell lines, which was significantly greater than the activity of hydroxymethylpentamethylmelamine (HMPMM), a major metabolite of HMM.
Animated Futurist Sculpting as Dynamic Implicit Shapes (2021)

In this work, we present an approach to obtain futurist sculptures. Our approach is inspired by the works of Italian Futurist artists such as Umberto Boccioni. Futurism, as an art movement, aims to achieve to define forms that are a product of time but is permanent in space. In this work, we have developed a methodology to produce a set of futurist sculptures from any given animation of any object that is defined as a triangular mesh. Each produced futurist sculpture is a still frame of what can be rendered as a sculpture animation. Our method is based on the conversion of a given polygonal mesh and its motion into an implicit shape in 4D space which consists of 3-spatial and one temporal dimension. To create each specific futurist sculpture, we compute a subset of this 4D implicit shape in a given time interval. The resulting immersion of 4D structure into the 3D spatial domain provides us desired futurist sculpture for the given time interval. The most important aspect of our methodology is the conversion of animated polygonal mesh into a 4D implicit shape. We first convert a polygonal mesh into a set of particles. Each particle can have its own color. All the points that are closer to the trajectory of the particle form an implicitly defined swept volume [Kim et al. 2004]. These swept volumes appear to be similar to the extrusion of a circle along a curve, but they are guaranteed to be free of artifacts caused by intersections.
Eyewitness Identification Evidence: Science And Reform (2005)

Kirk Bloodsworth was the first death row inmate to be exonerated by DNA evidence. Bloodsworth, a U.S. Marine veteran, had never been in trouble with the law, but was convicted in 1984 of the rape and murder of a 9-year-old girl and was sentenced to die in Maryland’s gas chamber. DNA tests exonerated Bloodsworth in 1993, but it was not until 2004 that the real killer was identified by DNA tests. The evidence driving Bloodsworth’s conviction was mistaken eyewitness identification.\nThere is little doubt today that mistaken eyewitness identification is the primary cause of the conviction of innocent people in the United States. The DNA exoneration cases, carefully tracked by the Innocence Project at the Cardozo School of Law, show that approximately 75 percent of these convictions of innocent persons were cases of mistaken eyewitness identification.1 Even before the development of forensic DNA tests, mistaken identification was shown to be responsible for the
Nuisance level of a voice call (2008)

In our everyday life, we communicate with many people such as family, friends, neighbors, and colleagues. We communicate with them using different communication media such as email, telephone calls, and face-to-face interactions. While email is not real-time and face-to-face communications require geographic proximity, voice and video communications are preferred over other modes of communication. However, real-time voice/video calls may create nuisance to the receiver. In this article, we describe a mathematical model for computing nuisance level of incoming voice/video calls. We computed the closeness and nuisance level using the calling patterns between the caller and the callee. To validate the nuisance model, we collected cell phone call records of real-life people at our university and computed the nuisance value for all voice calls. We validated the nuisance levels using the feedback from those real-life people. Such a nuisance model is useful for predicting unwanted voice and video sessions in an IP communication network.
How transparent film applied on dermatologic imaging devices in order to prevent infections affects image quality? (2018)

All tested films had excellent optical properties. However, some of them had better optical qualities and seemed more suitable for their use in dermatologic imaging.
Efficient implementation of 3D listless SPECK (2010)

This paper proposes an efficient algorithm for 3D image compression based on Set Partitioned Embedded Block Coding (SPECK). The new algorithm operates without a linked list and is suitable for implementation via hardware applications. 3D listless SPECK has a fixed, predetermined memory requirement that is larger than that required for the image alone. In the new developed algorithm, instead of a list, a state table with four bits per coefficient keeps track of the set partitions and the information that has been encoded. Sparse marking is applied to the selected block nodes of insignificant blocks in the state table. In this way, a large group of predictable insignificant coefficients can be identified and skipped during the coding process. The performance of the proposed listless algorithm is compared with 3D SPECK and the results obtained suggest that the proposed algorithm performs better for several images at various bit rates.
Hyperspectral microscopic imaging by multiplex coherent anti-Stokes Raman scattering (CARS) (2011)

Coherent anti-Stokes Raman scattering (CARS) microscopy is a powerful technique to image the chemical composition of complex samples in biophysics, biology and materials science. CARS is a four-wave mixing process. The application of a spectrally narrow pump beam and a spectrally wide Stokes beam excites multiple Raman transitions, which are probed by a probe beam. This generates a coherent directional CARS signal with several orders of magnitude higher intensity relative to spontaneous Raman scattering. Recent advances in the development of ultrafast lasers, as well as photonic crystal fibers (PCF), enable multiplex CARS. In this study, we employed two scanning imaging methods. In one, the detection is performed by a photo-multiplier tube (PMT) attached to the spectrometer. The acquisition of a series of images, while tuning the wavelengths between images, allows for subsequent reconstruction of spectra at each image point. The second method detects CARS spectrum in each point by a cooled coupled charged detector (CCD) camera. Coupled with point-by-point scanning, it allows for a hyperspectral microscopic imaging. We applied this CARS imaging system to study biological samples such as oocytes.
Towards Robotic Semantic Segmentation of Supporting Surfaces (2015)

Perceiving the geometry of environmental structures surrounding is a crucial prerequisite for robotic understand the indoor environments autonomously. A new framework for parsing RGB-D images aimed at supporting surfaces segmentation is proposed. First, the surface normal is extracted from depth information using PCA and normal clusters with 3D mean shift clustering. Then the main planes such as floor, wall will be detected with gravity vector estimation. Finally supporting surface and its corresponding objects are segmented using graph optimization with energy functions. The approach can offer a robotic semantic segmentation for better understanding the indoor environment. The experiment results based on Berkeley 3D Object Dataset demonstrate that our framework works well on indoor RGB-D cluttered scenes.