1119 A RE-ASSESSMENT OF 30-, 60- AND 90-DAY MORTALITY AFTER RADICAL PROSTATECTOMY (2012)

You have accessJournal of UrologyProstate Cancer: Localized V1 Apr 20121119 A RE-ASSESSMENT OF 30-, 60- AND 90-DAY MORTALITY AFTER RADICAL PROSTATECTOMY Jens Hansen, Maxine Sun, Marco Bianchi, Michael Rink, Nawar Hanna, Zhe Tian, Jan Schmitges, Quoc-Dien Trinh, Luis A. Kluth, Shahrokh F. Shariat, Paul Perrotte, Markus Graefen, and Pierre I. Karakiewicz Jens HansenJens Hansen Hamburg, Germany More articles by this author , Maxine SunMaxine Sun Montreal, Canada More articles by this author , Marco BianchiMarco Bianchi Milan, Italy More articles by this author , Michael RinkMichael Rink Hamburg, Germany More articles by this author , Nawar HannaNawar Hanna Montreal, Canada More articles by this author , Zhe TianZhe Tian Montreal, Canada More articles by this author , Jan SchmitgesJan Schmitges Hamburg, Germany More articles by this author , Quoc-Dien TrinhQuoc-Dien Trinh Detroit, MI More articles by this author , Luis A. KluthLuis A. Kluth Hamburg, Germany More articles by this author , Shahrokh F. ShariatShahrokh F. Shariat New York, NY More articles by this author , Paul PerrottePaul Perrotte Montreal, Canada More articles by this author , Markus GraefenMarkus Graefen Hamburg, Germany More articles by this author , and Pierre I. KarakiewiczPierre I. Karakiewicz Montreal, Canada More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2012.02.1228AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES To assess the rates of short-term mortality after radical prostatectomy. METHODS We assessed 30-, 60-, and 90-day mortality after RP in a population-based cohort of 63708 PCa patients treated up to 2005. Descriptive analyses for assessing the rates of 30-, 60- and 90- day mortality were performed. Univariable and multivariable logistic regression analyses were used to identify variables associated with the events. RESULTS Overall, the mean age was 69 years (median 69) Overall 30-, 60- and 90-day mortality was 0.4, 0.7 and 0.9%. In multivariable analyses, increasing age was associated with higher risk of 30-, 60- and 90-day mortality (>80yr vs <65yr; odds ratios (OR) 5.69, 6.97 and 6.68, respectively, all P <0.001). Sixty-day and 90-day mortality increased with increasing CCI score (CCI >3 vs CCI 0; OR 2.79 and 3.22, respectively, both P <0.001). Interestingly, CCI of 2 or higher was not significantly associated with 30-day mortality. Black race was associated with an increased risk of 60- and 90-day mortality (OR 1.84 and 1.59, respectively, both P <0.001) compared to whites, but not with 30-day mortality. No differences, predicting 30-, 60- or 90-day mortality, were found according to minimal-invasive vs open surgery. CONCLUSIONS It is noteworthy, that there is a non-negligible risk of short term mortality after RP. Especially increased age and multiple comorbidities are associated with higher risk of short-term mortality, especially within 60 and 90 days after RP. These findings should be taken into account in treatment decision making. © 2012 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 187Issue 4SApril 2012Page: e453-e454 Advertisement Copyright & Permissions© 2012 by American Urological Association Education and Research, Inc.Metrics Author Information Jens Hansen Hamburg, Germany More articles by this author Maxine Sun Montreal, Canada More articles by this author Marco Bianchi Milan, Italy More articles by this author Michael Rink Hamburg, Germany More articles by this author Nawar Hanna Montreal, Canada More articles by this author Zhe Tian Montreal, Canada More articles by this author Jan Schmitges Hamburg, Germany More articles by this author Quoc-Dien Trinh Detroit, MI More articles by this author Luis A. Kluth Hamburg, Germany More articles by this author Shahrokh F. Shariat New York, NY More articles by this author Paul Perrotte Montreal, Canada More articles by this author Markus Graefen Hamburg, Germany More articles by this author Pierre I. Karakiewicz Montreal, Canada More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...