gebhart/patrepeval huggingface dataset:
TCP14 and TCP15 affect internode length and leaf shape in Arabidopsis (2011)

TCP transcription factors constitute a small family of plant-specific bHLH-containing, DNA-binding proteins that have been implicated in the control of cell proliferation in plants. Despite the significant role that is likely to be played by genes that control cell division in the elaboration of plant architecture, functional analysis of this family by forward and reverse genetics has been hampered by genetic redundancy. Here we show that mutants in two related class I TCP genes display a range of growth-related phenotypes, consistent with their dynamic expression patterns; these phenotypes are enhanced in the double mutant. Together, the two genes influence plant stature by promoting cell division in young internodes. Reporter gene analysis and use of SRDX fusions suggested that TCP14 and TCP15 modulate cell proliferation in the developing leaf blade and specific floral tissues; a role that was not apparent in our phenotypic analysis of single or double mutants. However, when the relevant mutants were subjected to computer-aided morphological analysis of the leaves, the consequences of loss of either or both genes became obvious. The effects on cell proliferation of perturbing the function of TCP14 and TCP15 vary with tissue, as has been suggested for other TCP factors. These findings indicate that the precise elaboration of plant form is dependent on the cumulative influence of many TCP factors acting in a context-dependent fashion. The study highlights the need for advanced methods of phenotypic analysis in order to characterize phenotypes and to construct a dynamic model for TCP gene function.
Unveiling the Nucleation and Coarsening Mechanisms of Solution-Derived Self-Assembled Epitaxial Ce0.9Gd0.1O2–y Nanostructures (2016)

Self-assembling approaches based on chemical solution deposition (CSD) are ideal methods for the cost-effective production of epitaxial nanostructures with high throughput. Therefore, an in-depth investigation of the nucleation and coarsening processes involved in the self-assembly of nanostructures is mandatory to achieve a good control over nanostructure shape, dimensions, and orientation. Heteroepitaxial Ce0.9Gd0.1O2-y (CGO) is an ideal model system to unveil the underlying nanostructure development mechanisms in addition to their promising properties for catalysis, gas sensors, and ionic conductivity. Rapid thermal annealing furnaces have been used to study separately the thermodynamic and kinetic nucleation and coarsening mechanisms of self-assembled CGO isotropic and anisotropic nanostructures based on strain-engineering and surface energies control. Different CGO nanoislands are obtained: isotropic (001)CGO nanodots are grown on (001)-oriented Y2O3:ZrO2 (YSZ) and LaAlO3 (LAO) substrates, whereas (011)LAO substrates promote the growth of elongated (011)CGO nanowires. HRTEM and RHEED analyses are used to study the early stages of nucleation, as well as the shape and interfacial structure of CGO nanostructures. A systematic study with the heating ramp, annealing temperature and time, and strain in combination with thermally activated theoretical models provides information on the nucleation behavior, nucleation barriers, and atomic diffusion coefficients along in-plane and out-of-plane island orientations. Highly anisotropic atomic diffusion constants have been shown to be at the origin of the high aspect ratios of some of the nanostructures. Overall, our study provides a general method for the evaluation of nucleation and coarsening of multiple CSD-derived oxide nanostructures and understanding the shape development by combining thermodynamic and kinetic approaches.
Impact of Array Configuration on Head-Mounted Display Performance at mm Wave Bands (2023)

Immersing a user in life-like extended reality (XR) scenery using a head-mounted display (HMD) with a constrained form factor and hardware complexity requires remote rendering on a nearby edge server or computer. Millimeter-wave (mmWave) communication technology can provide sufficient data rate for wireless XR content transmission. However, mmWave channels exhibit severe sparsity in the angular domain. This means that distributed antenna arrays are required to cover a larger angular area and to combat outage during HMD rotation. At the same time, one would prefer fewer antenna elements/arrays for a lower complexity system. Therefore, it is important to evaluate the trade-off between the number of antenna arrays and the achievable performance to find a proper practical solution. This work presents indoor 28 GHz mmWave channel measurement data, collected during HMD mobility, and studies the dominant eigenmode (DE) gain. DE gain is a significant factor in under-standing system performance since mm Wave channel sparsity and eigenmode imbalance often results in provisioning the majority of the available power to the DE. Moreover, it provides the upper performance bounds for widely-adopted analog beamformers. We propose 3 performance metrics - gain trade-off, gain volatility, and minimum service trade-off - for evaluating the performance of a multi-array HMD and apply the metrics to indoor 28 GHz channel measurement data. Evaluation results indicate, that 3 arrays provide stable temporal channel gain. Adding a 4 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">th</sup> array further increases channel capacity, while any additional arrays do not significantly increase physical layer performance.
The Maintenance of Memory Plasma Cells (2019)

It is now well accepted that plasma cells can become long-lived (memory) plasma cells and secrete antibodies for months, years or a lifetime. However, the mechanisms involved in this process of humoral memory, which is crucial for both protective immunity and autoimmunity, still are not fully understood. This article will address a number of open questions. For example: Is longevity of plasma cells due to their intrinsic competence, extrinsic factors, or a combination of both? Which internal signals are involved in this process? What factors provide external support? What survival factors play a part in inflammation and autoreactive disease? Internal and external factors that contribute to the maintenance of memory long-lived plasma cells will be discussed. The aim is to provide useful additional information about the maintenance of protective and autoreactive memory plasma cells that will help researchers design effective vaccines for the induction of life-long protection against infectious diseases and to efficiently target pathogenic memory plasma cells.
Extended Lifetime <italic>In Vivo</italic> Pulse Stimulated Ultrasound Imaging (2017)

An on-demand long-lived ultrasound contrast agent that can be activated with single pulse stimulated imaging (SPSI) has been developed using hard shell liquid perfluoropentane filled silica 500-nm nanoparticles for tumor ultrasound imaging. SPSI was tested on LnCAP prostate tumor models in mice; tumor localization was observed after intravenous (IV) injection of the contrast agent. Consistent with enhanced permeability and retention, the silica nanoparticles displayed an extended imaging lifetime of 3.3±1 days (mean±standard deviation). With added tumor specific folate functionalization, the useful lifetime was extended to 12 ± 2 days; in contrast to ligand-based tumor targeting, the effect of the ligands in this application is enhanced nanoparticle retention by the tumor. This paper demonstrates for the first time that IV injected functionalized silica contrast agents can be imaged with an in vivo lifetime ~500 times longer than current microbubble-based contrast agents. Such functionalized long-lived contrast agents may lead to new applications in tumor monitoring and therapy.
Profiling and Role of Bioactive Molecules from Puntius sophore (Freshwater/Brackish Fish) Skin Mucus with Its Potent Antibacterial, Antiadhesion, and Antibiofilm Activities (2020)

Epidermal fish mucus comprises of diverse bioactive metabolites which plays an immense role in defense mechanisms and other important cellular activities. Primarily, this study aims to screen the unexplored mucus extract of <i>Puntius sophore</i><i>(P. sophore)</i> for its antagonistic potential against common pathogens, which are commonly implicated in foodborne and healthcare associated infections, with effects on their adhesion and biofilm formation. Profiling of the skin mucus was carried out by High Resolution-Liquid Chromatography Mass Spectrometry (HR-LCMS), followed by antibacterial activity and assessment of antibiofilm potency and efficacy on the development, formation, and texture of biofilms. Furthermore, bacterial cell damage, viability within the biofilm, checkerboard test, and cytotoxicity were also evaluated. As a result, <i>P. sophore</i> mucus extract was found to be effective against all tested strains. It also impedes the architecture of biofilm matrix by affecting the viability and integrity of bacterial cells within biofilms and reducing the total exopolysaccharide content. A synergy was observed between <i>P. sophore</i> mucus extract and gentamicin for <i>Escherichia coli</i><i>(E. coli)</i>, <i>Pseudomonas aeruginosa</i><i>(P. aeruginosa),</i> and <i>Bacillus subtilis</i><i>(B. subtilis),</i> whereas, an additive effect for <i>Staphylococcus aureus</i><i>(S. aureus)</i>. Thus, our findings represent the potent bioactivities of <i>P. sophore</i> mucus extract for the first time, which could be explored further as an alternative to antibiotics or chemically synthesized antibiofilm agents.
Integrated risk assessment and safety consideration during design of HRC workplaces (2017)

Human-Robot-Collaboration (HRC) is seen by many manufacturing enterprises as an opportunity to increase the automation level in their manufacturing without having to acquiesce in flexibility. Accordingly, many system integrators are confronted by an increasing demand for collaborative workplaces. However, system integrators are having difficulties to deliver such safe and efficient workplaces as is evident by the very low number of HRC cells in industry. This is due to the complexity of the safety standards and guidelines governing HRC, as well as the often negative impact of necessary safety measures on the key performance indicators (KPIs) of a collaborative workplace. In this paper, an iterative design method utilizing model-driven risk assessment and decision support is presented, that automatically identifies potential hazards in a workplace design and estimates the impact of necessary safety measures, with regard to the KPIs investment cost, operational cost, cycle time and flexibility.
Identification ofStaphylococcus aureusexotoxins by combined sodium dodecyl sulfate gel electrophoresis and matrix-assisted laser desorption/ ionization-time of flight mass spectrometry (2002)

Staphylococcus aureus is an important human pathogen whose pathogenesis involves the synthesis of cell wall associated virulence factors and secreted toxins with damaging effects on the host cells. Most of these pathogenic factors are synthesized in a growth-phase dependent manner as a response to environmental stress like heat, lack of nutrients or other deleterious conditions. Conventional identification of these pathogenic factors is based on Western blot analysis or enzyme-linked immunosorbent assay (ELISA) and is limited by the commercial availability of antibodies against these toxins. We report here the use of matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) mass spectrometry for monitoring the pathogenic factors of S. aureus. For the identification of pathogenic factors, a methicillin sensitive strain of S. aureus, ATCC-29213, was grown at 37°C or 42°C in brain-heart infusion broth and harvested during the early stationary phase of growth. Secreted proteins were separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, enzymatically digested with trypsin and analyzed by MALDI-TOF mass spectrometry. When grown at 42°C, alpha- and beta-hemolysins were found to accumulate in S. aureus supernatants while the concentration of protein A was slightly decreased. The identity of some of these toxins was confirmed by Western-blot analysis. MALDI-TOF mass spectrometry combined with sodium dodecyl sulfate gel electrophoresis represents a rapid and simple approach to characterize the virulence of S. aureus strains which seems to be particularly valuable for the identification of S. aureus exotoxins for which ELISA is not established.
Generating Shorter Bases for Hard Random Lattices. (2008)

We revisit the problem of generating a “hard” random lattice together with a basis of relatively short vectors. This problem has gained in importance lately due to new cryptographic schemes that use such a procedure for generating public/secret key pairs. In these applications, a shorter basis directly corresponds to milder underlying complexity assumptions and smaller key sizes. The contributions of this work are twofold. First, using the Hermite normal form as an organizing principle, we simplify and generalize an approach due to Ajtai (ICALP 1999). Second, we improve the construction and its analysis in several ways, most notably by tightening the length of the output basis essentially to the optimum value.
Herstellung von monodispersen Polydimethylsiloxan-Netzwerken und Charakterisierung der Mikrostruktur und der Permeationseigenschaften (2006)

Entsprechend der Theorie des freien Volumens hinsichtlich der Diffusion in Kautschuken wird der Diffusionskoeffizient einer permeierenden Substanz im hohen Maße von der Mikrostruktur eines Kautschuks bestimmt. Daher war es Ziel dieser Arbeit Polydimethylsiloxannetzwerke mit definierten Mikrostrukturen zu entwickeln. Die Abhängigkeit der Permeationsprozesse von der Mikrostruktur der Netzwerke, sowie die Abhängigkeit dieser Prozesse von den physiko-chemischen Eigenschaften permeierender Substanzen wurde untersucht. Ein besseres Verständnis dieser Zusammenhänge kann zu Fortschritten in der Entwicklung von nichtporösen homogenen Membranen führen. Derartige Membranen werden unter anderem als Kontrollelement in therapeutischen Systemen oder in der Separationstechnik eingesetzt.
PERSIA for Direct Fluorescence Measurements of Transcription, Translation, and Enzyme Activity in Cell-Free Systems (2019)

Quantification of biology's central dogma (transcription and translation) is pursued by a variety of methods. Direct, immediate, and ongoing quantification of these events is difficult to achieve. Common practice is to use fluorescent or luminescent proteins to report indirectly on prior cellular events, such as turning on a gene in a genetic circuit. We present an alternative approach, PURExpress-ReAsH-Spinach In-vitro Analysis (PERSIA). PERSIA provides information on the production of RNA and protein during cell-free reactions by employing short RNA and peptide tags. Upon synthesis, these tags yield quantifiable fluorescent signal without interfering with other biochemical events. We demonstrate the applicability of PERSIA in measuring cell-free transcription, translation, and other enzymatic activity in a variety of applications: from sequence-structure-function studies, to genetic code engineering, to testing antiviral drug resistance.
Sialic acid in normal and arthritic human synovial fluids (1958)

Abstract The authors report careful and significant studies of the synovial fluid concentrations of sialic acid, a term which is applied to a group of related compounds first isolated from saliva. The nature of such compounds is reviewed. Since available methods for determining sialic acid are not specific, two colorimetric procedures were applied. A critical discussion of methodology is presented. Increased concentrations of sialic acid were observed in both the synovial fluids and sera of rheumatoid patients. Le autores reporta meticulose e significative studios in re le concentration—in le fluido synovial—del si‐appellate acido sialic. Iste termino es applicate a un gruppo de inter‐relationate compositos primo isolate ab specimens de saliva. Le natura de tal compositos es passate in revista. Viste que le nunc disponibile methodos pro determinar acido sialic non es specific, duo technicas colorimetric esseva applicate. Es presentate un discussion critic del methodologia. Augmentate concentrationes de acido sialic esseva observate in le fluidos synovial e in le seros de patientes rheumatoide.
Interrogating a statistic: HIV prevalence rates in PNG (2009)

"This discussion paper interrogates recent estimates of HIV prevalence in PNG and explores the relevance of international conceptualisations of HIV epidemics to the situation in PNG. It contributes to the quest to ‘Know your epidemic, know your response’, in particular in PNG contexts (UNAIDS 2007a: 10). The global endeavour to better ‘know your epidemic, know your response’ constitutes recognition that there are many diverse HIV epidemics and many different ways of responding to them. No single account captures their diversity. No single response keeps them at bay. Our understanding of an epidemic needs to guide us towards effective responses. So far this has not happened to any great extent. In 2007 globally some 2.5 million people became newly infected (UNAIDS 2007b: 1) ... " - page 1
Learning the piece-wise constant graph structure of a varying Ising model (2019)

This work focuses on the estimation of multiple change-points in a time-varying Ising model that evolves piece-wise constantly. The aim is to identify both the moments at which significant changes occur in the Ising model, as well as the underlying graph structures. For this purpose, we propose to estimate the neighborhood of each node by maximizing a penalized version of its conditional log-likelihood. The objective of the penalization is twofold: it imposes sparsity in the learned graphs and, thanks to a fused-type penalty, it also enforces them to evolve piece-wise constantly. Using few assumptions, we provide two change-points consistency theorems. Those are the first in the context of unknown number of change-points detection in time-varying Ising model. Finally, experimental results on several synthetic datasets and a real-world dataset demonstrate the performance of our method.
Miniature transmitter for implantable micro systems (2004)

This paper considers design of a miniature transmitter operating with near-field inductive coupling, in the context of embedded electronic systems in medical diagnosis, environmental monitoring, and other industrial applications. Recent developments in system-on-chip and lab-on-a-chip technologies made the implementation of such miniaturized systems feasible, and pose an interesting set of problems with respect to low-power, short-range wireless communications. The design of a compact transmitter with a magnetic antenna is discussed and some early results are presented.
Transient RNA structure features are evolutionarily conserved and can be computationally predicted (2013)

Functional RNA structures tend to be conserved during evolution. This finding is, for example, exploited by comparative methods for RNA secondary structure prediction that currently provide the state-of-art in terms of prediction accuracy. We here provide strong evidence that homologous RNA genes not only fold into similar final RNA structures, but that their folding pathways also share common transient structural features that have been evolutionarily conserved. For this, we compile and investigate a non-redundant data set of 32 sequences with known transient and final RNA secondary structures and devise a dedicated computational analysis pipeline.
Extraction of saponin from Camellia oleifera cake and evaluation of its antioxidant activity (2012)

Summary Response surface methodology was employed to optimise extraction conditions of saponins from Camellia oleifera cake. Optimal conditions were extraction at 82.2 °C for 3.3 h with an 8.6:1 ratio (mL g −1 ) of solvent to solid. The saponin extract was further extracted with n‐butanol, and nine saponins were found as the main components. The identification of these saponins was carried out by HPLC–ESI–MS, and their possible structures were given. Antioxidant activities of the saponins were evaluated in vitro by 1,1‐diphenyl‐2‐picryl‐hydrazyl (DPPH), 1, 2, 3‐phentriol self‐oxidation and metal chelating activity assays. IC 50 value of each assay was 3866 ± 3, 4744 ± 2 and 2389 ± 2 μg mL −1 , respectively. The effects of environmental factors on antioxidant activity of saponins from C. oleifera cake were studied for the first time. The antioxidant activity is pH dependent with 9.0 as the optimal pH and is also temperature independent.
Plasma Science and Technology (2013)

For high-voltage direct current (HVDC) power grid transmission with higher voltage, the energy consuming branch of the DC circuit breaker is required to dissipate huge energy of more than megajoules in a short time in case of fault and short circuit. The energy consuming equipment based on ZnO is difficult to meet the requirements for its huge volume and weight. In this paper, a new energy consumption method based on gallium indium tin (GaInSn) liquid metal in the arcing process is proposed, and a test platform with adjustable short-circuit current is built. The triggering mechanism of GaInSn liquid metal arcing energy consumption is studied. It is found that short-circuit current and channel aperture are the key parameters affecting the energy consumption of liquid metal arcing. The characteristics of GaInSn liquid metal energy consumption are investigated, and four stages of liquid metal energy consumption are found: oscillatory shrinkage, arc breakdown, arc burning phase change, and arc extinguishment. The influence of short-circuit current and channel aperture on the energy consumption characteristics of GaInSn liquid metal is investigated. To further explore the physical mechanism of the above phenomena, a magneto-hydrodynamic model of energy consumption in the GaInSn liquid metal arcing process is established. The influence of short-circuit current and channel aperture on the temperature distribution of liquid metal arc is analyzed. The effect mechanism of short-circuit current and channel aperture on arc temperature peak and temperature diffusion rate is clarified. The research results provide theoretical support for the new liquid metal energy consumption mode of the DC circuit breaker.&#xD;Keywords： GaInSn liquid metal, trigger mechanism, oscillatory shrinkage, arcing energy consumption, temperature diffusion.&#xD
Femtosecond Switching of the Solid-State Phase Transition in VO2 (1994)

We have measured the transient change in the optical parameters of VO 2 thin films for laser excitation through the first-order phase transition near 68° C. Femtosecond laser excitation at 780 nm from an amplified, passively modelocked Ti:sapphire laser was used in a pulse-probe configuration to excite the VO 2 film through the semiconducting to metallic phase transition. The transient reflection and transmission were measured on a femtosecond and picosecond time range by a delayed probe pulse also at 780 nm. We have transformed the raw measurements of dynamic reflection and transmission to complex refractive index using a thin film model.
An Electrolytic Saw for Preparing Strain-Free Metal Specimens (1970)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Herbert M. Einbinder; An Electrolytic Saw for Preparing Strain‐Free Metal Specimens. Rev. Sci. Instrum. 1 November 1970; 41 (11): 1660–1661. https://doi.org/10.1063/1.1684370 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioReview of Scientific Instruments Search Advanced Search |Citation Search