gebhart/patrepeval huggingface dataset:
A multifunctional composite material with piezoresistivity and mechanoluminescence properties for a wearable sensor (2023)

Intelligent composite materials and devices are attracting a great interest owing to their potential impact on various future life applications. To meet the growing demand for multifunctional materials, the development and validation of visible sensing behavior is highly desirable, but the development of a single multifunctional wearable sensing material still remains a challenge to be achieved. To reach this goal, here we present a wearable intelligent fabric with piezoresistivity and mechanoluminescence ability based on a layer-structured graphene-based conductive cotton fabric and SrAl2O4:Eu2+, Dy3+/polyurethane foamed coating. The presence of the foamed coating structure endows the flexible composite fabric with a controllable positive/negative piezoresistivity (gauge factor from −2.5 to 17) and a bright mechanoluminescence ability that can be used in the darkness without additional batteries. Three-dimensional chromaticity diagrams have also been developed as advanced tools to quantitatively assess the luminescence, whose lightness, during the bending cycles, is highly repeatable with value in the range from ∼25 to ∼55. The multifunctional layered composite sensor provides multiple output signals which can be accurately recognized and assigned to independent triggering events, opening up new opportunities in advanced wearable devices based on commercial fabrics.
In vitro aerosol delivery by vibrating mesh nebulizer (VMN) and pressurized metered dose inhaler (pMDI) using spacers in comparison with T adapters in mechanical ventilation. (2020)

<i>In vitro</i> performance of spacers were evaluated in comparison with T adapters in adult and paediatric mechanical ventilation models. With the ventilator set in volume controlled (VC) mode with adult breathing parameters, aerosol delivery by pMDI (Ventolin, GSK) was compared when using a spacer (CombiHaler<sup>®</sup>, Laboratoire optimHal-ProtecSom; Aerochamber MV<sup>®</sup>, AeroVent<sup>®</sup>&nbsp;and Aerochamber Mini<sup>®</sup>, Trudell Medical) instead of a T adapter (Intersurgical). Aerosol delivery by nebulization was compared when using a spacer instead of a T adapter (Aeroneb Solo<sup>®</sup> T piece, Aerogen).With the ventilator set in VC mode with peadiatric breathing parameters (corresponding to a child of 15kg weight), aerosol delivery by pMDI was compared when using a spacer (MinimHal<sup>®</sup>, Laboratoire OptimHal-ProtecSom) instead of a MDI adapter (Intersurgical) and aerosol delivery by nebulization was compared when using a spacer (MinimHal<sup>®</sup>) instead of a T adapter (Aeroneb Solo<sup>®</sup> peadiatric T piece). Using the adult model, Aerosol delivery by nebulization increased when using the spacer (42.75&nbsp;± 4.48 % vs 35.26&nbsp;± 7.44 %). Aerosol delivery by pMDI increased up to two or three-fold when using the spacer instead of an MDI adapter.Using the peadiatric model, aerosol delivery by nebulization was higher with the spacer than with the T&nbsp;piece (23.84&nbsp;± 7.72 % 15.06&nbsp;± 4.18 %). Aerosol delivery by pMDI increased by up to three-fold when using the spacer in comparison to the T adapter (9.45&nbsp;± 2.27 % vs 2.94&nbsp;± 0.34%). In this <i>in vitro</i> study, using a spacer instead of a T adapter with both a pMDI and a VMN increased drug delivery.
Relative orientation of close-packed β-pleated sheets in proteins (1981)

When beta-pleated sheets pack face to face in proteins, the angle between the strand directions of the two beta-sheets is observed to be near -30 degrees . We propose a simple model for beta-sheet-to-beta-sheet packing in concanavalin A, plastocyanin, gamma-crystallin, superoxide dismutase, prealbumin, and the immunoglobin fragment V(REI). This model shows how the observed relative orientation of two packed beta-sheets is a consequence of (i) the rows of side chains at the interface being approximately aligned and (ii) the beta-sheet having a right-handed twist. The special amino acid composition of residues at the beta-sheet-to-beta-sheet interfaces makes the contact surfaces essentially smooth and hydrophobic.
Review of optical performance monitoring techniques (2008)

The optical performance monitoring technique is of critical importance for the future development of dynamic WDM networks. In this paper, we review its current status and future challenges.
Graft invariant natural killer T-cell dose predicts risk of acute graft-versus-host disease in allogeneic hematopoietic stem cell transplantation (2012)

Invariant natural killer T (iNKT) cells are powerful immunomodulatory cells that in mice regulate a variety of immune responses, including acute GVHD (aGVHD). However, their clinical relevance and in particular their role in clinical aGVHD are not known. We studied whether peripheral blood stem cell (PBSC) graft iNKT-cell dose affects on the occurrence of clinically significant grade II-IV aGVHD in patients (n = 57) undergoing sibling, HLA-identical allogeneic HSCT. In multivariate analysis, CD4(-) iNKT-cell dose was the only graft parameter to predict clinically significant aGVHD. The cumulative incidence of grade II-IV aGVHD in patients receiving CD4(-) iNKT-cell doses above and below the median were 24.2% and 71.4%, respectively (P = .0008); low CD4(-) iNKT-cell dose was associated with a relative risk of grade II-IV aGVHD of 4.27 (P = .0023; 95% CI, 1.68-10.85). Consistent with a role of iNKT cells in regulating aGVHD, in mixed lymphocyte reaction assays, CD4(-) iNKT cells effectively suppressed T-cell proliferation and IFN-γ secretion in a contact-dependent manner. In conclusion, higher doses of CD4(-) iNKT cells in PBSC grafts are associated with protection from aGVHD. This effect could be harnessed for prevention of aGVHD.
Identification of the IFN-β response in H3N2 canine influenza virus infection (2015)

Canine influenza viruses (CIVs) circulate continuously in the dog population, providing opportunities for exposure to humans and other species. Although the dog genome has been sequenced, innate immunity in dogs is not well characterized, which limits the understanding of H3N2 canine influenza virus pathogenesis. Equally, how this virus evades the canine host innate immune response to successfully establish infection remains unclear. To analyse the IFN-β response to CIV infection in Madin-Darby canine kidney cells, the canine IFN-β promoter sequence and its positive regulatory domain motifs were first cloned and identified using a luciferase reporter system. Next, we found that infection with the CIV strain GD/12 blocked the IFN-β response primarily by inhibiting the NF-κB and IFN regulatory factor 3 (IRF3) signalling pathways. Expression of GD/12 non-structural protein 1 alone was sufficient to inhibit Sendai virus-induced NF-κB and IRF3 activation by suppressing p65 and IRF3 phosphorylation, suggesting the important role of this protein in the CIV-mediated inhibition of the IFN-β response. These results suggest that inhibition of the IFN-β signalling pathway may have played a role in CIV establishment and spread in dog populations.
A SUITABLE MEDIUM FOR IN VITRO SEED PROPAGATION OF DENDROBIUM HYBRIDS (2015)

Dendrobium is the most popular orchid in Thailand according to its economic value. In order to increase the volume of sales, new hybrids need to be releasedat all time. Thus seed germination and propagation are very important steps to obtain the new cultivars from orchid breeders. An experiment compared 5 different seed sowing media: Hyponex (H), Knudson C (KC), Vacin and Went (VW), Murashige and Skoog (MS) and Â¼MS on seed germination and development of two Dendrobium hybrids. Seeds of D. antennatum A D. phalaenopsis and D. Louis Bleriot had highest germination percentage of 95 and 85%, respectively, on Hyponex medium. Moreover, two months after seed sowing, protocorms of both Dendrobium hybrids were highly developed on Hyponex medium as measured by protocorm diameter and fresh weight, compared to the other sowing media. Hyponex medium is the most effective medium for seed germination and development in these two Dendrobium hybrids.
A cooperative TDMA MAC protocol using dynamic slot assignment scheme (2013)

In this paper, we propose and analyze a cooperative TDMA MAC protocol with dynamic slot assignment. Our protocol allows a source node to retransmit failed packet cooperatively during a neighbor node's idle slot. The source node can select idle slots for a cooperative retransmission by a simple control packet exchange among neighbor nodes. The neighbor nodes that have the failed packet transmit during the selected slot at the same time. If there are no idle slots available, the cooperative retransmission is attempted during the source node's time slot. The throughput of TDMA can be significantly improved by the proposed cooperative retransmission scheme at the expense of increased overhead. We formulate an analytic model for the proposed protocol for implementation over Rayleigh fading channels and validate it by simulation. The results show that the throughput of TDMA systems is improved significantly if there are a sufficient number of idle slots available for cooperative retransmission, even though overhead is introduced.
Cardiovascular safety of exenatide BID: an integrated analysis from controlled clinical trials in participants with type 2 diabetes (2011)

GLP-1 receptor agonist, diabetes, cardiovascular safety.
Efficacy of l-Carnitine for Fatigue in Cancer Patients (2007)

Because carnitine is a necessary substrate for energy metabolism, a deficiency in this amino acid derivative is hypothesized to contribute to fatigue in chronic illness. Cancer patients can be deficient in carnitine because of low oral intake as well as high renal loss associated with chemotherapy. Investigators in New York conducted a phase I/II study to evaluate l-carnitine supplementation in adults with advanced cancer and moderate-to-severe fatigue.

To establish the safety and efficacy …
Scour in Stormwater Catchbasin Devices – Experimental Results from a Full-Scale Physical Model (2009)

Hydrodynamic devices have long been proposed as sediment traps in storm drainage systems. The earliest, and simplest, hydrodynamic device is an inlet with a ca…
Erratum for Mesplède et al., “The R263K Dolutegravir Resistance-Associated Substitution Progressively Decreases HIV-1 Integration” (2018)

Volume 8, no. 2, e00157-17, 2017, [https://doi.org/10.1128/mBio.00157-17][1]. One source of funding for our study was not properly acknowledged. The acknowledgment section of the manuscript should read:

We regret to note that Mark A. Wainberg passed away in April 2017. Therefore, the corresponding
Tunable stellate mesoporous silica nanoparticles for intracellular drug delivery (2014)

Stellate mesoporous silica nanoparticles with special radial pore morphology were easily synthesized using triethanolamine as the base catalyst in a wide range of synthesis conditions. By adjusting the surfactant composition, reaction temperature and time, and reagent ratio, the particle size of the material could be tailored continuously ranging from 50 to 140 nm and the pore size from 2 to 20 nm. By analyzing the effects of different synthesis parameters, it is concluded that the particles are formed following a nucleation-growth mechanism and the reaction kinetics play an important role in determining the particle size and pore structure. These stellate MSNs can be conveniently functionalized with a nontoxic low molecular weight poly(ethylene imine) (PEI, 800 Da) by a delayed condensation method. The resulting nanocomposites not only possess auto-fluorescence for suitable particle tracking but also demonstrate good potential for intracellular delivery of the anticancer doxorubicin drug.
Conceptual design of a proton computed tomography system for applications in proton radiation therapy (2004)

Proton computed tomography (pCT) has the potential to improve the accuracy of dose calculations for proton treatment planning, and will also be useful for pretreatment verification of patient positioning relative to the proton beam. A design study was performed to define the optimal approach to a pCT system based on specifications for applications in proton therapy. Conceptual and detailed design of a pCT system is presented; the system consists of a silicon-based particle tracking system and a crystal calorimeter to measure energy loss of individual protons. We discuss the formation of pCT images based on the reconstruction of volume electron density maps and the suitability of analytic and statistical algorithms for image reconstruction.
Compact Electro-Optic Single Sideband Modulators Utilizing Miniaturized Branch-Line Couplers on LiNbO<sub>3</sub> Substrate (2015)

Optical single sideband (SSB) modulation with the Mach-Zehnder (MZ) interferometer was realized by integrating the modulation electrode with the branch-line coupler (BLC) as a 90-degree hybrid onto the modulator substrate. In this paper, BLCs of the microsrtip-line structure were miniaturized on modulator substrates, LiNbO3 (LN), to realize more compact optical SSB modulators. We introduced two techniques of miniaturizing the BLC, one is using periodically installed open-circuited stabs and the other is installing series capacitors. Compared with a conventional pattern of the BLC, an area of the miniaturized BLC by using periodically installed open-circuited stubs was reduced to about 50%, and that by installing series capacitors was done to about 60%. The operation of these miniaturized BLCs was experimentally confirmed as the 90-degree hybrid at around 10GHz. Output ports of each miniaturized BLC were directly connected with the modulation electrode on the modulator substrate. Thereby, we fabricated two types of compact SSB modulators for 1550nm light wavelength. In the experiments, the optical SSB modulation was successfully confirmed by the output light spectra and the sideband suppression ratio of more than 30dB were observed.
Latency and Tumorigenesis in Marek's Disease (2013)

Despite the remarkable progress in our understanding of Marek's disease (MD) and the causative Marek's disease virus (MDV) biology, a number of major features of this complex viral disease remain unknown. Significant information on critical aspects of virus latency in lymphoid cells, and the virus-host interaction in MDV-induced lymphoma, remains to be identified. Moreover, the nature of the unique milieu of the feather follicle epithelial cell that allows cytolytic infection to continue, despite maintaining the latent infection in the lymphoid cells, is not fully understood. Although there has been significant progress in our understanding of the functions of a number of viral genes in the pathogenesis of the disease, the characteristics of the latent infection, how it differs from tumor phase, and whether latency is a prerequisite for the tumor phase are all important questions still to be answered. Reticuloendotheliosis virus-transformed cell lines have been shown to support MDV latency in a manner almost identical to that seen in MDV-transformed cell lines. There are increasing data on the role of epigenetic regulation, including DNA methylation and histone modifications, in maintaining viral latency. Onset of MD tumor is relatively rapid, and recent studies based on chromosomal integration and T-cell repertoire analysis demonstrated the clonal nature of MD lymphomas. Among the viral determinants of oncogenicity, the basic leucine zipper protein Meq is considered to be the most important and the most extensively studied. Deleting the Meq proteins or abolishing some of the important interactions does affect the oncogenicity of the virus. In addition, the noncoding sequences in the viral genome, such as the viral telomerase RNA and the virus-encoded microRNAs, also have significant influence on MDV-encoded oncogenesis.
Poly(maleic anhydride) cross-linked polyimide aerogels: synthesis and properties (2016)

A series of aerogels was fabricated by cross-linking amine end-capped polyimide oligomers with poly(maleic anhydride)s.
Tolérance et réponse adaptive au stress acide chez Lactobacillus bulgaricus (2002)

*INRA Centre de Jouy-en-Josas (FRA) Diffusion du document : INRA Centre de Jouy-en-Josas (FRA)
Rapid Inactivation of Ovalbumin Messenger Ribonucleic Acid after Acute Withdrawal of Estrogen (1974)

Synthesis of ovalbumin mRNA is induced and maintained in the avian oviduct by estrogen. When estrogen is rapidly removed from circulation, there is a general involution of the oviduct and an unusually rapid decay of ovalbumin mRNA activity. The kinetics of ovalbumin mRNA decay were not first order; instead, the rate of degradation increased about 10-fold over a 20-hr period after removal of estrogen. These results are in contrast with first-order decay kinetics observed for ovalbumin mRNA in estrogen-stimulated chicks (t(1/2) = about 24 hr) and in cell-free extracts. The degradative response triggered by hormonal withdrawal becomes more rapid between 1 and 4 days of estrogen-stimulated growth. We conclude that in the process of inducing egg-white protein synthesis, estrogen produces a cellular environment in which the egg-white protein mRNAs are relatively stable; removal of estrogen initiates cellular catabolism in a manner that is not understood.
Classification of human activity based on smartphone inertial sensor using support vector machine (2017)

The aim of this paper is to compare the performance of different kernel of classification support vector machine classification for classifying the physical daily living activities. Thirty subjects from a database performed activities such as walking, sitting, standing, laying, walking upstairs and downstairs. Inertial sensors signals ((accelerometer, gyroscope and magnetometer) from the smartphone are used to measure the human movements for each activity. The inertial sensor data were processed using signal processing method with several features of time domain and frequency domain. Multiclass support vector machine polynomial kernel (MC-SVM-Polynomial) and multiclass support vector machine Linear Kernel (MC-SVM-Linear) using One Versus All (OVA) methods were employed. These classification methods are assessed using the performance criteria such as precision percentage, recall percentage and correct accuracy classification rate percentage using 10-fold cross validation procedure. The results show that MC-SVM-Polynomial produces the best result with 98.57% compared to MC-SVM-Linear with 97.04% based on correct accuracy classification rate.
同性婚姻合法化歷程：美國經驗，臺灣借鑒 (2017)

同性戀是自古至今一直存在的「敏感」人群與議題，同時，根據權威研究數據，其比例約占總人口的3％﹣5％，如此龐大的人口基數下，該群體人口數量不容小覷。經過漫長的認知與爭論，自2001年起，歐美國家掀起同性婚姻合法化的浪潮，隨著 2014 年 12 月 19 日，臺灣婚姻平權民法修正案一讀通過，2015年美國成為同性婚姻合法的國家之一，同性婚姻合法化再次成為焦點。 本文採用文獻探討法、個案研究法、歷史研究法，以美國與臺灣的同性婚姻合法化發展歷程為研究對象，探討其發展的背景與過程、其阻力與爭議、發展的推動力、是否存在決定性因素。
 通過研究，美國的歷程大致可分為三個階段，第一階段為17世紀初至19世紀中期，即1607至1850年代第二次工業革命，此為明令禁止的迫害時代；第二階段為19世纪中期至20世纪中期，即1850至1960年代，此為同性戀運動的醞釀時代，在此期間工業革命興起，城市化進程加劇，同性戀組織萌芽並發展、活動，美國社會對同性戀者態度開始發生轉變；第三階段為20世纪60年代至20世纪末，即1960年代至1996年，此為同性戀運動之抗爭與接納时代，同性戀者爭取個人層面平等權利，開始擺脫污名融入社會主流；第四階段為20世纪末至今，此為争取婚姻權階段，各州陸續出臺同性婚姻相關法案，直至2015年，同性婚姻在美國全國合法。
 縱觀整個過程，其阻力主要在於宗教教義、傳統家庭結構與滑坡理論。發展過程中推動因素為社會運動浪潮、兩黨政治選舉、文化產業發展、訴訟案件、同性戀維權組織及其領袖之推動。
 臺灣發展進程分為兩個階段，第一階段為1980至1990年代，因著特殊的時代背景，同志運動起步。該時期多個組織建立，在社會對立的複雜環境中摸索抗爭與發聲，力求人權與平等。第二階段為公元2000年至今，是同志運動多面開花，蓬勃發展的時期。臺灣成為亞洲同志運動先鋒地區，訴求同性婚姻合法化。
 臺灣阻礙因素除了與美國相似的宗教教義、家庭結構、滑坡理論爭議，還存在中國傳統婚姻觀、對同性戀群體刻板印象的阻礙。臺灣同性婚姻合法化進程中的推動力量包括歐美國家同性婚姻合法化潮流、臺灣政治選舉、文化產業發展、同性戀維權組織及其領袖的作用。
 研究發現：一、美國同性婚姻合法化進程中，民意是決定性的因素。二、臺灣同志團體發展相較於美國存在不足之處，推動方式較為薄弱與單一，有待完善。因此，針對提高民意支持率，研究建議：一、臺灣同志維權團體需形成同盟、共享資源、有計劃地發展；二、爭取號召社會知名人士、權威性學者的支持並其發聲。三、建設自己優質且有廣泛影響的發聲平臺，需善用社群網站與新聞媒體，建設專門網站、專門雜誌報刊。四、善用選舉政治與政黨輪替的契機。五、臺灣的發展之路可考慮「同志個人層面權益保障﹣『民事結合』的伴侶關係﹣同性婚姻合法」的路徑。
Surface perturbation of vibrational transitions of pyrenesilanes bound to silica gel (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSurface perturbation of vibrational transitions of pyrenesilanes bound to silica gelM. L. Hunnicutt, J. M. Harris, and C. H. LochmuellerCite this: J. Phys. Chem. 1985, 89, 24, 5246–5250Publication Date (Print):November 1, 1985Publication History Published online1 May 2002Published inissue 1 November 1985https://pubs.acs.org/doi/10.1021/j100270a025https://doi.org/10.1021/j100270a025research-articleACS PublicationsRequest reuse permissionsArticle Views124Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Diethyl 2-oxo-4,5-diphenylcyclopentane-1,3-dicarboxylate (2001)

The title compound, C23H20O5, is one of a series of soluble precursors to electroluminescent conjugated polymers as well as leading to helical structures. The geometries of the ring systems are within normal limits, as are those of the ethyl esters. There are few close contacts within the mol­ecule, leading one to rationalize the overall geometry arising from pure steric interactions without any attractive forces such as hydrogen bonding.
Charge-induced formation of linear Au clusters on thin MgO films: Scanning tunneling microscopy and density-functional theory study (2008)

Gold deposition onto ultrathin MgO films on Ag(001) results in the formation of linear Au clusters, as revealed from a combined scanning tunneling microscopy and density-functional theory study. The equilibrium structure of small Au clusters containing three to seven atoms is therefore different on thin film and bulk MgO(001) but also deviates from the shape of the respective gas-phase clusters. The peculiar one-dimensional growth regime of gold is stimulated by an electron transfer from the MgO/Ag interface to the deposited Au clusters, resulting in singly and doubly charged cluster anions. Only for larger atom numbers, the formation of compact two-dimensional clusters prevails on the MgO thin films.